{"text_format":"3","workbook":"xlsx","n_sheets":5,"sheets":["Sheet1","Sheet2","Sheet3","Sheet4","Sheet5"],"read":"whole","date_system":"1900"}

{"sheet":"Sheet1","index":0,"n_rows":9,"n_cols":7,"rows_kept":9}
["Dataset","Data type","WHO Grade II","WHO Grade III"," WHO Grade IV","Source","PMID"]
["CGGA","RNA-seq",291,334,388,"http://www.cgga.org.cn/download.jsp",28291232]
["TCGA-GBMLGG","RNA-seq",226,244,150,"http://firebrowse.org/?cohort=GBMLGG&download_dialog=true#",26824661]
["Rembrandt","Microarray",98,85,130,"https://gdoc.georgetown.edu/gdoc/",19208739]
["GSE16011","Microarray",24,85,159,"http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE16011",19920198]
["GSE4412","Microarray",null,26,59,"http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE4412",15374961]
["GSE43289","Microarray",3,6,28,"http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE43289",20484145]
[]
["Total",null,642,780,914]

{"sheet":"Sheet2","index":1,"n_rows":783,"n_cols":3,"rows_kept":783}
["Metagene","Cell type","Immunity"]
["ADAM28","Activated B cell","Adaptive"]
["CD180","Activated B cell","Adaptive"]
["CD79B","Activated B cell","Adaptive"]
["BLK","Activated B cell","Adaptive"]
["CD19","Activated B cell","Adaptive"]
["MS4A1","Activated B cell","Adaptive"]
["TNFRSF17","Activated B cell","Adaptive"]
["IGHM","Activated B cell","Adaptive"]
["GNG7","Activated B cell","Adaptive"]
["MICAL3","Activated B cell","Adaptive"]
["SPIB","Activated B cell","Adaptive"]
["HLA-DOB","Activated B cell","Adaptive"]
["IGKC","Activated B cell","Adaptive"]
["PNOC","Activated B cell","Adaptive"]
["FCRL2","Activated B cell","Adaptive"]
["BACH2","Activated B cell","Adaptive"]
["CR2","Activated B cell","Adaptive"]
["TCL1A","Activated B cell","Adaptive"]
["AKNA","Activated B cell","Adaptive"]
["ARHGAP25","Activated B cell","Adaptive"]
["CCL21","Activated B cell","Adaptive"]
["CD27","Activated B cell","Adaptive"]
["CD38","Activated B cell","Adaptive"]
["CLEC17A","Activated B cell","Adaptive"]
["CLEC9A","Activated B cell","Adaptive"]
["CLECL1","Activated B cell","Adaptive"]
["AIM2","Activated CD4 T cell","Adaptive"]
["BIRC3","Activated CD4 T cell","Adaptive"]
["BRIP1","Activated CD4 T cell","Adaptive"]
["CCL20","Activated CD4 T cell","Adaptive"]
["CCL4","Activated CD4 T cell","Adaptive"]
["CCL5","Activated CD4 T cell","Adaptive"]
["CCNB1","Activated CD4 T cell","Adaptive"]
["CCR7","Activated CD4 T cell","Adaptive"]
["DUSP2","Activated CD4 T cell","Adaptive"]
["ESCO2","Activated CD4 T cell","Adaptive"]
["ETS1","Activated CD4 T cell","Adaptive"]
["EXO1","Activated CD4 T cell","Adaptive"]
["EXOC6","Activated CD4 T cell","Adaptive"]
["IARS","Activated CD4 T cell","Adaptive"]
["ITK","Activated CD4 T cell","Adaptive"]
["KIF11","Activated CD4 T cell","Adaptive"]
["KNTC1","Activated CD4 T cell","Adaptive"]
["NUF2","Activated CD4 T cell","Adaptive"]
["PRC1","Activated CD4 T cell","Adaptive"]
["PSAT1","Activated CD4 T cell","Adaptive"]
["RGS1","Activated CD4 T cell","Adaptive"]
["RTKN2","Activated CD4 T cell","Adaptive"]
["SAMSN1","Activated CD4 T cell","Adaptive"]
["SELL","Activated CD4 T cell","Adaptive"]
["TRAT1","Activated CD4 T cell","Adaptive"]
["ADRM1","Activated CD8 T cell","Adaptive"]
["AHSA1","Activated CD8 T cell","Adaptive"]
["C1GALT1C1","Activated CD8 T cell","Adaptive"]
["CCT6B","Activated CD8 T cell","Adaptive"]
["CD37","Activated CD8 T cell","Adaptive"]
["CD3D","Activated CD8 T cell","Adaptive"]
["CD3E","Activated CD8 T cell","Adaptive"]
["CD3G","Activated CD8 T cell","Adaptive"]
["CD69","Activated CD8 T cell","Adaptive"]
["CD8A","Activated CD8 T cell","Adaptive"]
["CETN3","Activated CD8 T cell","Adaptive"]
["CSE1L","Activated CD8 T cell","Adaptive"]
["GEMIN6","Activated CD8 T cell","Adaptive"]
["GNLY","Activated CD8 T cell","Adaptive"]
["GPT2","Activated CD8 T cell","Adaptive"]
["GZMA","Activated CD8 T cell","Adaptive"]
["GZMH","Activated CD8 T cell","Adaptive"]
["GZMK","Activated CD8 T cell","Adaptive"]
["IL2RB","Activated CD8 T cell","Adaptive"]
["LCK","Activated CD8 T cell","Adaptive"]
["MPZL1","Activated CD8 T cell","Adaptive"]
["NKG7","Activated CD8 T cell","Adaptive"]
["PIK3IP1","Activated CD8 T cell","Adaptive"]
["PTRH2","Activated CD8 T cell","Adaptive"]
["TIMM13","Activated CD8 T cell","Adaptive"]
["ZAP70","Activated CD8 T cell","Adaptive"]
["ABHD3","Central memory CD4 T cell","Adaptive"]
["AHNAK","Central memory CD4 T cell","Adaptive"]
["ANXA2P2","Central memory CD4 T cell","Adaptive"]
["AQP3","Central memory CD4 T cell","Adaptive"]
["ATHL1","Central memory CD4 T cell","Adaptive"]
["BMI1","Central memory CD4 T cell","Adaptive"]
["BZW2","Central memory CD4 T cell","Adaptive"]
["CD63","Central memory CD4 T cell","Adaptive"]
["COL4A1","Central memory CD4 T cell","Adaptive"]
["CYLD","Central memory CD4 T cell","Adaptive"]
["ELMO2","Central memory CD4 T cell","Adaptive"]
["FYN","Central memory CD4 T cell","Adaptive"]
["GLIPR1","Central memory CD4 T cell","Adaptive"]
["GSS","Central memory CD4 T cell","Adaptive"]
["IFITM2","Central memory CD4 T cell","Adaptive"]
["ITGB1","Central memory CD4 T cell","Adaptive"]
["ITGB2","Central memory CD4 T cell","Adaptive"]
["KLF5","Central memory CD4 T cell","Adaptive"]
["LSP1","Central memory CD4 T cell","Adaptive"]
["NDUFB9","Central memory CD4 T cell","Adaptive"]
["PKM2","Central memory CD4 T cell","Adaptive"]
["SFXN3","Central memory CD4 T cell","Adaptive"]
["SIRPG","Central memory CD4 T cell","Adaptive"]
["SMAD4","Central memory CD4 T cell","Adaptive"]
["STX4","Central memory CD4 T cell","Adaptive"]
["TRADD","Central memory CD4 T cell","Adaptive"]
["VIM","Central memory CD4 T cell","Adaptive"]
["XRCC6","Central memory CD4 T cell","Adaptive"]
["ACTN4","Central memory CD8 T cell","Adaptive"]
["ADAM12","Central memory CD8 T cell","Adaptive"]
["ADCY9","Central memory CD8 T cell","Adaptive"]
["F13A1","Central memory CD8 T cell","Adaptive"]
["FCER1G","Central memory CD8 T cell","Adaptive"]
["FCGR3B","Central memory CD8 T cell","Adaptive"]
["FGF7","Central memory CD8 T cell","Adaptive"]
["FKBP4","Central memory CD8 T cell","Adaptive"]
["GLUD1","Central memory CD8 T cell","Adaptive"]
["GM2A","Central memory CD8 T cell","Adaptive"]
["GUSB","Central memory CD8 T cell","Adaptive"]
["IL1RN","Central memory CD8 T cell","Adaptive"]
["NOL11","Central memory CD8 T cell","Adaptive"]
["NTRK1","Central memory CD8 T cell","Adaptive"]
["RARA","Central memory CD8 T cell","Adaptive"]
["RNF128","Central memory CD8 T cell","Adaptive"]
["SIGLEC1","Central memory CD8 T cell","Adaptive"]
["TNFRSF11A","Central memory CD8 T cell","Adaptive"]
["TOX4","Central memory CD8 T cell","Adaptive"]
["UBA52","Central memory CD8 T cell","Adaptive"]
["ULBP1","Central memory CD8 T cell","Adaptive"]
["ATM","Effector memeory CD4 T cell","Adaptive"]
["CASP3","Effector memeory CD4 T cell","Adaptive"]
["CASQ1","Effector memeory CD4 T cell","Adaptive"]
["CD300E","Effector memeory CD4 T cell","Adaptive"]
["DARS","Effector memeory CD4 T cell","Adaptive"]
["DOCK9","Effector memeory CD4 T cell","Adaptive"]
["EXOSC9","Effector memeory CD4 T cell","Adaptive"]
["EZH2","Effector memeory CD4 T cell","Adaptive"]
["GDE1","Effector memeory CD4 T cell","Adaptive"]
["IL34","Effector memeory CD4 T cell","Adaptive"]
["NCOA4","Effector memeory CD4 T cell","Adaptive"]
["NEFL","Effector memeory CD4 T cell","Adaptive"]
["PDGFRL","Effector memeory CD4 T cell","Adaptive"]
["PTGS1","Effector memeory CD4 T cell","Adaptive"]
["REPS1","Effector memeory CD4 T cell","Adaptive"]
["SCG2","Effector memeory CD4 T cell","Adaptive"]
["SDPR","Effector memeory CD4 T cell","Adaptive"]
["SIGLEC14","Effector memeory CD4 T cell","Adaptive"]
["SIGLEC6","Effector memeory CD4 T cell","Adaptive"]
["TAL1","Effector memeory CD4 T cell","Adaptive"]
["TFEC","Effector memeory CD4 T cell","Adaptive"]
["TIPIN","Effector memeory CD4 T cell","Adaptive"]
["TPK1","Effector memeory CD4 T cell","Adaptive"]
["UQCRB","Effector memeory CD4 T cell","Adaptive"]
["USP9Y","Effector memeory CD4 T cell","Adaptive"]
["WIPF1","Effector memeory CD4 T cell","Adaptive"]
["ZCRB1","Effector memeory CD4 T cell","Adaptive"]
["ACAP1","Effector memeory CD8 T cell","Adaptive"]
["APOL3","Effector memeory CD8 T cell","Adaptive"]
["ARHGAP10","Effector memeory CD8 T cell","Adaptive"]
["ATP10D","Effector memeory CD8 T cell","Adaptive"]
["C3AR1","Effector memeory CD8 T cell","Adaptive"]
["CCR5","Effector memeory CD8 T cell","Adaptive"]
["CD160","Effector memeory CD8 T cell","Adaptive"]
["CD55","Effector memeory CD8 T cell","Adaptive"]
["CFLAR","Effector memeory CD8 T cell","Adaptive"]
["CMKLR1","Effector memeory CD8 T cell","Adaptive"]
["DAPP1","Effector memeory CD8 T cell","Adaptive"]
["FCRL6","Effector memeory CD8 T cell","Adaptive"]
["FLT3LG","Effector memeory CD8 T cell","Adaptive"]
["GZMM","Effector memeory CD8 T cell","Adaptive"]
["HAPLN3","Effector memeory CD8 T cell","Adaptive"]
["HLA-DMB","Effector memeory CD8 T cell","Adaptive"]
["HLA-DPA1","Effector memeory CD8 T cell","Adaptive"]
["HLA-DPB1","Effector memeory CD8 T cell","Adaptive"]
["IFI16","Effector memeory CD8 T cell","Adaptive"]
["LIME1","Effector memeory CD8 T cell","Adaptive"]
["LTK","Effector memeory CD8 T cell","Adaptive"]
["NFKBIA","Effector memeory CD8 T cell","Adaptive"]
["SETD7","Effector memeory CD8 T cell","Adaptive"]
["SIK1","Effector memeory CD8 T cell","Adaptive"]
["TRIB2","Effector memeory CD8 T cell","Adaptive"]
["ACP5","Gamma delta T cell","Adaptive"]
["AQP9","Gamma delta T cell","Adaptive"]
["BTN3A2","Gamma delta T cell","Adaptive"]
["C1orf54","Gamma delta T cell","Adaptive"]
["CARD8","Gamma delta T cell","Adaptive"]
["CCL18","Gamma delta T cell","Adaptive"]
["CD209","Gamma delta T cell","Adaptive"]
["CD33","Gamma delta T cell","Adaptive"]
["CD36","Gamma delta T cell","Adaptive"]
["CDK5","Gamma delta T cell","Adaptive"]
["IL10RB","Gamma delta T cell","Adaptive"]
["KLRF1","Gamma delta T cell","Adaptive"]
["LGALS1","Gamma delta T cell","Adaptive"]
["MAPK7","Gamma delta T cell","Adaptive"]
["KLHL7","Gamma delta T cell","Adaptive"]
["KRT80","Gamma delta T cell","Adaptive"]
["LAMC1","Gamma delta T cell","Adaptive"]
["LCORL","Gamma delta T cell","Adaptive"]
["LMNB1","Gamma delta T cell","Adaptive"]
["MEIS3P1","Gamma delta T cell","Adaptive"]
["MPL","Gamma delta T cell","Adaptive"]
["FABP1","Gamma delta T cell","Adaptive"]
["FABP5","Gamma delta T cell","Adaptive"]
["FADD","Gamma delta T cell","Adaptive"]
["MFAP3L","Gamma delta T cell","Adaptive"]
["MINPP1","Gamma delta T cell","Adaptive"]
["RPS24","Gamma delta T cell","Adaptive"]
["RPS7","Gamma delta T cell","Adaptive"]
["RPS9","Gamma delta T cell","Adaptive"]
["DBNL","Gamma delta T cell","Adaptive"]
["CCL13","Gamma delta T cell","Adaptive"]
["CD22","Immature  B cell","Adaptive"]
["CYBB","Immature  B cell","Adaptive"]
["FAM129C","Immature  B cell","Adaptive"]
["FCRL1","Immature  B cell","Adaptive"]
["FCRL3","Immature  B cell","Adaptive"]
["FCRL5","Immature  B cell","Adaptive"]
["FCRLA","Immature  B cell","Adaptive"]
["HDAC9","Immature  B cell","Adaptive"]
["HLA-DQA1","Immature  B cell","Adaptive"]
["HVCN1","Immature  B cell","Adaptive"]
["KIAA0226","Immature  B cell","Adaptive"]
["NCF1","Immature  B cell","Adaptive"]
["NCF1B","Immature  B cell","Adaptive"]
["P2RY10","Immature  B cell","Adaptive"]
["SP100","Immature  B cell","Adaptive"]
["TXNIP","Immature  B cell","Adaptive"]
["STAP1","Immature  B cell","Adaptive"]
["TAGAP","Immature  B cell","Adaptive"]
["ZCCHC2","Immature  B cell","Adaptive"]
["AICDA","Memory B cell","Adaptive"]
["CCNA2","Memory B cell","Adaptive"]
["CDKN3","Memory B cell","Adaptive"]
["CLCN5","Memory B cell","Adaptive"]
["ENPP1","Memory B cell","Adaptive"]
["FCER1A","Memory B cell","Adaptive"]
["FCRL4","Memory B cell","Adaptive"]
["MYC","Memory B cell","Adaptive"]
["RUNX2","Memory B cell","Adaptive"]
["SORL1","Memory B cell","Adaptive"]
["SOX5","Memory B cell","Adaptive"]
["STAT5A","Memory B cell","Adaptive"]
["STAT5B","Memory B cell","Adaptive"]
["TLR9","Memory B cell","Adaptive"]
["CCL3L1","Regulatory T cell","Adaptive"]
["CD72","Regulatory T cell","Adaptive"]
["CLEC5A","Regulatory T cell","Adaptive"]
["FOXP3","Regulatory T cell","Adaptive"]
["ITGA4","Regulatory T cell","Adaptive"]
["L1CAM","Regulatory T cell","Adaptive"]
["LIPA","Regulatory T cell","Adaptive"]
["LRP1","Regulatory T cell","Adaptive"]
["LRRC42","Regulatory T cell","Adaptive"]
["MARCO","Regulatory T cell","Adaptive"]
["MMP12","Regulatory T cell","Adaptive"]
["MNDA","Regulatory T cell","Adaptive"]
["MRC1","Regulatory T cell","Adaptive"]
["MS4A6A","Regulatory T cell","Adaptive"]
["PELO","Regulatory T cell","Adaptive"]
["PLEK","Regulatory T cell","Adaptive"]
["PRSS23","Regulatory T cell","Adaptive"]
["PTGIR","Regulatory T cell","Adaptive"]
["ST8SIA4","Regulatory T cell","Adaptive"]
["STAB1","Regulatory T cell","Adaptive"]
["B3GAT1","T follicular helper cell","Adaptive"]
["CDK5R1","T follicular helper cell","Adaptive"]
["PDCD1","T follicular helper cell","Adaptive"]
["BCL6","T follicular helper cell","Adaptive"]
["CD200","T follicular helper cell","Adaptive"]
["CD83","T follicular helper cell","Adaptive"]
["CD84","T follicular helper cell","Adaptive"]
["FGF2","T follicular helper cell","Adaptive"]
["GPR18","T follicular helper cell","Adaptive"]
["CEBPA","T follicular helper cell","Adaptive"]
["CECR1","T follicular helper cell","Adaptive"]
["CLEC10A","T follicular helper cell","Adaptive"]
["CLEC4A","T follicular helper cell","Adaptive"]
["CSF1R","T follicular helper cell","Adaptive"]
["CTSS","T follicular helper cell","Adaptive"]
["DMN","T follicular helper cell","Adaptive"]
["DPP4","T follicular helper cell","Adaptive"]
["LRRC32","T follicular helper cell","Adaptive"]
["MC5R","T follicular helper cell","Adaptive"]
["MICA","T follicular helper cell","Adaptive"]
["NCAM1","T follicular helper cell","Adaptive"]
["NCR2","T follicular helper cell","Adaptive"]
["NRP1","T follicular helper cell","Adaptive"]
["PDCD1LG2","T follicular helper cell","Adaptive"]
["PDCD6","T follicular helper cell","Adaptive"]
["PRDX1","T follicular helper cell","Adaptive"]
["RAE1","T follicular helper cell","Adaptive"]
["RAET1E","T follicular helper cell","Adaptive"]
["SIGLEC7","T follicular helper cell","Adaptive"]
["SIGLEC9","T follicular helper cell","Adaptive"]
["TYRO3","T follicular helper cell","Adaptive"]
["CHST12","T follicular helper cell","Adaptive"]
["CLIC3","T follicular helper cell","Adaptive"]
["IVNS1ABP","T follicular helper cell","Adaptive"]
["KIR2DL2","T follicular helper cell","Adaptive"]
["LGMN","T follicular helper cell","Adaptive"]
["CD70","Type 1 T helper cell","Adaptive"]
["TBX21","Type 1 T helper cell","Adaptive"]
["ADAM8","Type 1 T helper cell","Adaptive"]
["AHCYL2","Type 1 T helper cell","Adaptive"]
["ALCAM","Type 1 T helper cell","Adaptive"]
["B3GALNT1","Type 1 T helper cell","Adaptive"]
["BBS12","Type 1 T helper cell","Adaptive"]
["BST1","Type 1 T helper cell","Adaptive"]
["CD151","Type 1 T helper cell","Adaptive"]
["CD47","Type 1 T helper cell","Adaptive"]
["CD48","Type 1 T helper cell","Adaptive"]
["CD52","Type 1 T helper cell","Adaptive"]
["CD53","Type 1 T helper cell","Adaptive"]
["CD59","Type 1 T helper cell","Adaptive"]
["CD6","Type 1 T helper cell","Adaptive"]
["CD68","Type 1 T helper cell","Adaptive"]
["CD7","Type 1 T helper cell","Adaptive"]
["CD96","Type 1 T helper cell","Adaptive"]
["CFHR3","Type 1 T helper cell","Adaptive"]
["CHRM3","Type 1 T helper cell","Adaptive"]
["CLEC7A","Type 1 T helper cell","Adaptive"]
["COL23A1","Type 1 T helper cell","Adaptive"]
["COL4A4","Type 1 T helper cell","Adaptive"]
["COL5A3","Type 1 T helper cell","Adaptive"]
["DAB1","Type 1 T helper cell","Adaptive"]
["DLEU7","Type 1 T helper cell","Adaptive"]
["DOC2B","Type 1 T helper cell","Adaptive"]
["EMP1","Type 1 T helper cell","Adaptive"]
["F12","Type 1 T helper cell","Adaptive"]
["FURIN","Type 1 T helper cell","Adaptive"]
["GAB3","Type 1 T helper cell","Adaptive"]
["GATM","Type 1 T helper cell","Adaptive"]
["GFPT2","Type 1 T helper cell","Adaptive"]
["GPR25","Type 1 T helper cell","Adaptive"]
["GREM2","Type 1 T helper cell","Adaptive"]
["HAVCR1","Type 1 T helper cell","Adaptive"]
["HSD11B1","Type 1 T helper cell","Adaptive"]
["HUNK","Type 1 T helper cell","Adaptive"]
["IGF2","Type 1 T helper cell","Adaptive"]
["RCSD1","Type 1 T helper cell","Adaptive"]
["RYR1","Type 1 T helper cell","Adaptive"]
["SAV1","Type 1 T helper cell","Adaptive"]
["SELE","Type 1 T helper cell","Adaptive"]
["SELP","Type 1 T helper cell","Adaptive"]
["SH3KBP1","Type 1 T helper cell","Adaptive"]
["SIT1","Type 1 T helper cell","Adaptive"]
["SLC35B3","Type 1 T helper cell","Adaptive"]
["SIGLEC10","Type 1 T helper cell","Adaptive"]
["SKAP1","Type 1 T helper cell","Adaptive"]
["THUMPD2","Type 1 T helper cell","Adaptive"]
["TIGIT","Type 1 T helper cell","Adaptive"]
["ZEB2","Type 1 T helper cell","Adaptive"]
["ENC1","Type 1 T helper cell","Adaptive"]
["FAM134B","Type 1 T helper cell","Adaptive"]
["FBXO30","Type 1 T helper cell","Adaptive"]
["FCGR2C","Type 1 T helper cell","Adaptive"]
["STAC","Type 1 T helper cell","Adaptive"]
["LTC4S","Type 1 T helper cell","Adaptive"]
["MAN1B1","Type 1 T helper cell","Adaptive"]
["MDH1","Type 1 T helper cell","Adaptive"]
["MMD","Type 1 T helper cell","Adaptive"]
["RGS16","Type 1 T helper cell","Adaptive"]
["IL12A","Type 1 T helper cell","Adaptive"]
["P2RX5","Type 1 T helper cell","Adaptive"]
["CD97","Type 1 T helper cell","Adaptive"]
["ITGB4","Type 1 T helper cell","Adaptive"]
["ICAM3","Type 1 T helper cell","Adaptive"]
["METRNL","Type 1 T helper cell","Adaptive"]
["TNFRSF1A","Type 1 T helper cell","Adaptive"]
["IRF1","Type 1 T helper cell","Adaptive"]
["HTR2B","Type 1 T helper cell","Adaptive"]
["CALD1","Type 1 T helper cell","Adaptive"]
["MOCOS","Type 1 T helper cell","Adaptive"]
["TRAF3IP2","Type 1 T helper cell","Adaptive"]
["TLR8","Type 1 T helper cell","Adaptive"]
["TRAF1","Type 1 T helper cell","Adaptive"]
["DUSP14","Type 1 T helper cell","Adaptive"]
["IL17A","Type 17 T helper cell","Adaptive"]
["IL17RA","Type 17 T helper cell","Adaptive"]
["C2CD4A","Type 17 T helper cell","Adaptive"]
["C2CD4B","Type 17 T helper cell","Adaptive"]
["CA2","Type 17 T helper cell","Adaptive"]
["CCDC65","Type 17 T helper cell","Adaptive"]
["CEACAM3","Type 17 T helper cell","Adaptive"]
["IL17C","Type 17 T helper cell","Adaptive"]
["IL17F","Type 17 T helper cell","Adaptive"]
["IL17RC","Type 17 T helper cell","Adaptive"]
["IL17RE","Type 17 T helper cell","Adaptive"]
["IL23A","Type 17 T helper cell","Adaptive"]
["ILDR1","Type 17 T helper cell","Adaptive"]
["LONRF3","Type 17 T helper cell","Adaptive"]
["SH2D6","Type 17 T helper cell","Adaptive"]
["TNIP2","Type 17 T helper cell","Adaptive"]
["ABCA1","Type 17 T helper cell","Adaptive"]
["ABCB1","Type 17 T helper cell","Adaptive"]
["ADAMTS12","Type 17 T helper cell","Adaptive"]
["ANK1","Type 17 T helper cell","Adaptive"]
["ANKRD22","Type 17 T helper cell","Adaptive"]
["B3GALT2","Type 17 T helper cell","Adaptive"]
["CAMTA1","Type 17 T helper cell","Adaptive"]
["CCR9","Type 17 T helper cell","Adaptive"]
["CD40","Type 17 T helper cell","Adaptive"]
["GPR44","Type 17 T helper cell","Adaptive"]
["IFT80","Type 17 T helper cell","Adaptive"]
["ASB2","Type 2 T helper cell","Adaptive"]
["CSRP2","Type 2 T helper cell","Adaptive"]
["DAPK1","Type 2 T helper cell","Adaptive"]
["DLC1","Type 2 T helper cell","Adaptive"]
["DNAJC12","Type 2 T helper cell","Adaptive"]
["DUSP6","Type 2 T helper cell","Adaptive"]
["GNAI1","Type 2 T helper cell","Adaptive"]
["LAMP3","Type 2 T helper cell","Adaptive"]
["NRP2","Type 2 T helper cell","Adaptive"]
["OSBPL1A","Type 2 T helper cell","Adaptive"]
["PDE4B","Type 2 T helper cell","Adaptive"]
["PHLDA1","Type 2 T helper cell","Adaptive"]
["PLA2G4A","Type 2 T helper cell","Adaptive"]
["RAB27B","Type 2 T helper cell","Adaptive"]
["RBMS3","Type 2 T helper cell","Adaptive"]
["RNF125","Type 2 T helper cell","Adaptive"]
["TMPRSS3","Type 2 T helper cell","Adaptive"]
["GATA3","Type 2 T helper cell","Adaptive"]
["BIRC5","Type 2 T helper cell","Adaptive"]
["CDC25C","Type 2 T helper cell","Adaptive"]
["CDC7","Type 2 T helper cell","Adaptive"]
["CENPF","Type 2 T helper cell","Adaptive"]
["CXCR6","Type 2 T helper cell","Adaptive"]
["DHFR","Type 2 T helper cell","Adaptive"]
["EVI5","Type 2 T helper cell","Adaptive"]
["GSTA4","Type 2 T helper cell","Adaptive"]
["HELLS","Type 2 T helper cell","Adaptive"]
["IL26","Type 2 T helper cell","Adaptive"]
["LAIR2","Type 2 T helper cell","Adaptive"]
["ABCD1","Activated dendritic cell","Innate"]
["C1QC","Activated dendritic cell","Innate"]
["CAPG","Activated dendritic cell","Innate"]
["CCL3L3","Activated dendritic cell","Innate"]
["CD207","Activated dendritic cell","Innate"]
["CD302","Activated dendritic cell","Innate"]
["ATP5B","Activated dendritic cell","Innate"]
["ATP5L","Activated dendritic cell","Innate"]
["ATP6V1A","Activated dendritic cell","Innate"]
["BCL2L1","Activated dendritic cell","Innate"]
["C1QB","Activated dendritic cell","Innate"]
["SNURF","Activated dendritic cell","Innate"]
["SPCS3","Activated dendritic cell","Innate"]
["CCNA1","Activated dendritic cell","Innate"]
["CEACAM8","Activated dendritic cell","Innate"]
["NOS2","Activated dendritic cell","Innate"]
["SRA1","Activated dendritic cell","Innate"]
["TNFRSF6B","Activated dendritic cell","Innate"]
["TREM1","Activated dendritic cell","Innate"]
["TREML1","Activated dendritic cell","Innate"]
["RHOA","Activated dendritic cell","Innate"]
["SLC25A37","Activated dendritic cell","Innate"]
["TNFSF14","Activated dendritic cell","Innate"]
["TREML4","Activated dendritic cell","Innate"]
["VNN2","Activated dendritic cell","Innate"]
["XPO6","Activated dendritic cell","Innate"]
["CLEC4C","Activated dendritic cell","Innate"]
["TNFAIP2","Activated dendritic cell","Innate"]
["UBD","Activated dendritic cell","Innate"]
["ACTR3","Activated dendritic cell","Innate"]
["RAB1A","Activated dendritic cell","Innate"]
["SLA","Activated dendritic cell","Innate"]
["HLA-DQA2","Activated dendritic cell","Innate"]
["SIGLEC5","Activated dendritic cell","Innate"]
["SLAMF9","Activated dendritic cell","Innate"]
["ABAT","CD56bright natural killer cell","Innate"]
["C11orf75","CD56bright natural killer cell","Innate"]
["C5orf15","CD56bright natural killer cell","Innate"]
["CDHR1","CD56bright natural killer cell","Innate"]
["DCAF12","CD56bright natural killer cell","Innate"]
["DYNLL1","CD56bright natural killer cell","Innate"]
["GPR137B","CD56bright natural killer cell","Innate"]
["HCP5","CD56bright natural killer cell","Innate"]
["HDGFRP2","CD56bright natural killer cell","Innate"]
["KRT86","CD56bright natural killer cell","Innate"]
["MLST8","CD56bright natural killer cell","Innate"]
["ELMOD3","CD56bright natural killer cell","Innate"]
["ENTPD5","CD56bright natural killer cell","Innate"]
["FAM119A","CD56bright natural killer cell","Innate"]
["FAM179A","CD56bright natural killer cell","Innate"]
["CLIC2","CD56bright natural killer cell","Innate"]
["COX7A2L","CD56bright natural killer cell","Innate"]
["CREB3L4","CD56bright natural killer cell","Innate"]
["CSF1","CD56bright natural killer cell","Innate"]
["CSNK2A2","CD56bright natural killer cell","Innate"]
["CSTA","CD56bright natural killer cell","Innate"]
["CSTB","CD56bright natural killer cell","Innate"]
["CTPS","CD56bright natural killer cell","Innate"]
["CTSD","CD56bright natural killer cell","Innate"]
["FST","CD56bright natural killer cell","Innate"]
["GATA2","CD56bright natural killer cell","Innate"]
["GMPR","CD56bright natural killer cell","Innate"]
["HDC","CD56bright natural killer cell","Innate"]
["HEY1","CD56bright natural killer cell","Innate"]
["HOXA1","CD56bright natural killer cell","Innate"]
["HS2ST1","CD56bright natural killer cell","Innate"]
["HS3ST1","CD56bright natural killer cell","Innate"]
["BCL11B","CD56bright natural killer cell","Innate"]
["CDH3","CD56bright natural killer cell","Innate"]
["MYL6B","CD56bright natural killer cell","Innate"]
["NAA16","CD56bright natural killer cell","Innate"]
["ClQA","CD56bright natural killer cell","Innate"]
["ClQB","CD56bright natural killer cell","Innate"]
["CYP27B1","CD56bright natural killer cell","Innate"]
["EIF3M","CD56bright natural killer cell","Innate"]
["CYP27A1","CD56dim natural killer cell","Innate"]
["DDX55","CD56dim natural killer cell","Innate"]
["DYRK2","CD56dim natural killer cell","Innate"]
["RPL37A","CD56dim natural killer cell","Innate"]
["NOTCH3","CD56dim natural killer cell","Innate"]
["AKR7A3","CD56dim natural killer cell","Innate"]
["GPRC5C","CD56dim natural killer cell","Innate"]
["GRIN1","CD56dim natural killer cell","Innate"]
["HLA-E","CD56dim natural killer cell","Innate"]
["PORCN","CD56dim natural killer cell","Innate"]
["PSMC4","CD56dim natural killer cell","Innate"]
["UPP1","CD56dim natural killer cell","Innate"]
["IL21R","CD56dim natural killer cell","Innate"]
["KIR2DS1","CD56dim natural killer cell","Innate"]
["KIR2DS2","CD56dim natural killer cell","Innate"]
["KIR2DS5","CD56dim natural killer cell","Innate"]
["GIPR","Eosinophil","Innate"]
["KRT18P50","Eosinophil","Innate"]
["LRMP","Eosinophil","Innate"]
["FOSB","Eosinophil","Innate"]
["RRP12","Eosinophil","Innate"]
["GPR183","Eosinophil","Innate"]
["NR4A3","Eosinophil","Innate"]
["ST3GAL6","Eosinophil","Innate"]
["DEPDC5","Eosinophil","Innate"]
["PDE6C","Eosinophil","Innate"]
["PKD2L2","Eosinophil","Innate"]
["GPR65","Eosinophil","Innate"]
["IL5RA","Eosinophil","Innate"]
["P2RY14","Eosinophil","Innate"]
["DACH1","Eosinophil","Innate"]
["DAPK2","Eosinophil","Innate"]
["EMR3","Eosinophil","Innate"]
["ACADM","Immature dendritic cell","Innate"]
["AHCYL1","Immature dendritic cell","Innate"]
["ALDH1A2","Immature dendritic cell","Innate"]
["ALDH3A2","Immature dendritic cell","Innate"]
["ALDH9A1","Immature dendritic cell","Innate"]
["ALOX15","Immature dendritic cell","Innate"]
["AMT","Immature dendritic cell","Innate"]
["ARL1","Immature dendritic cell","Innate"]
["ATIC","Immature dendritic cell","Innate"]
["ATP5A1","Immature dendritic cell","Innate"]
["CAPZA1","Immature dendritic cell","Innate"]
["LILRA5","Immature dendritic cell","Innate"]
["RDX","Immature dendritic cell","Innate"]
["RRAGD","Immature dendritic cell","Innate"]
["TACSTD2","Immature dendritic cell","Innate"]
["INPP5F","Immature dendritic cell","Innate"]
["RAB38","Immature dendritic cell","Innate"]
["PLAU","Immature dendritic cell","Innate"]
["CSF3R","Immature dendritic cell","Innate"]
["SLC18A2","Immature dendritic cell","Innate"]
["AMPD2","Immature dendritic cell","Innate"]
["CLTB","Immature dendritic cell","Innate"]
["C1orf162","Immature dendritic cell","Innate"]
["AIF1","Macrophage","Innate"]
["CCL1","Macrophage","Innate"]
["CCL14","Macrophage","Innate"]
["CCL23","Macrophage","Innate"]
["CCL26","Macrophage","Innate"]
["CD300LB","Macrophage","Innate"]
["CNR1","Macrophage","Innate"]
["CNR2","Macrophage","Innate"]
["EIF1","Macrophage","Innate"]
["EIF4A1","Macrophage","Innate"]
["FPR1","Macrophage","Innate"]
["FPR2","Macrophage","Innate"]
["FRAT2","Macrophage","Innate"]
["GPR27","Macrophage","Innate"]
["GPR77","Macrophage","Innate"]
["RNASE2","Macrophage","Innate"]
["MS4A2","Macrophage","Innate"]
["BASP1","Macrophage","Innate"]
["IGSF6","Macrophage","Innate"]
["HK3","Macrophage","Innate"]
["VNN1","Macrophage","Innate"]
["FES","Macrophage","Innate"]
["NPL","Macrophage","Innate"]
["FZD2","Macrophage","Innate"]
["FAM198B","Macrophage","Innate"]
["HNMT","Macrophage","Innate"]
["SLC15A3","Macrophage","Innate"]
["CD4","Macrophage","Innate"]
["TXNDC3","Macrophage","Innate"]
["FRMD4A","Macrophage","Innate"]
["CRYBB1","Macrophage","Innate"]
["HRH1","Macrophage","Innate"]
["WNT5B","Macrophage","Innate"]
["ADAMTS3","Mast cell","Innate"]
["CPA3","Mast cell","Innate"]
["CMA1","Mast cell","Innate"]
["CTSG","Mast cell","Innate"]
["ARHGAP15","Mast cell","Innate"]
["CPM","Mast cell","Innate"]
["FCN1","Mast cell","Innate"]
["FTL","Mast cell","Innate"]
["HSPA6","Mast cell","Innate"]
["ITGA9","Mast cell","Innate"]
["RNASE3","Mast cell","Innate"]
["S100A4","Mast cell","Innate"]
["SIGLEC8","Mast cell","Innate"]
["SLC6A4","Mast cell","Innate"]
["PTGS2","Mast cell","Innate"]
["EGR3","Mast cell","Innate"]
["PILRA","Mast cell","Innate"]
["CCR2","MDSC","Innate"]
["CD14","MDSC","Innate"]
["CD2","MDSC","Innate"]
["CD86","MDSC","Innate"]
["CXCR4","MDSC","Innate"]
["FCGR2A","MDSC","Innate"]
["FCGR2B","MDSC","Innate"]
["FCGR3A","MDSC","Innate"]
["FERMT3","MDSC","Innate"]
["GPSM3","MDSC","Innate"]
["IL18BP","MDSC","Innate"]
["IL4R","MDSC","Innate"]
["ITGAL","MDSC","Innate"]
["ITGAM","MDSC","Innate"]
["PARVG","MDSC","Innate"]
["PSAP","MDSC","Innate"]
["PTGER2","MDSC","Innate"]
["PTGES2","MDSC","Innate"]
["S100A8","MDSC","Innate"]
["S100A9","MDSC","Innate"]
["ASGR2","Monocyte","Innate"]
["CFP","Monocyte","Innate"]
["ASGR1","Monocyte","Innate"]
["CD1D","Monocyte","Innate"]
["UPK3A","Monocyte","Innate"]
["ACTG1","Monocyte","Innate"]
["ANXA5","Monocyte","Innate"]
["ATP6V1B2","Monocyte","Innate"]
["CFL1","Monocyte","Innate"]
["DAZAP2","Monocyte","Innate"]
["CTBS","Monocyte","Innate"]
["EMR4P","Monocyte","Innate"]
["HIVEP2","Monocyte","Innate"]
["MARCKSL1","Monocyte","Innate"]
["MBP","Monocyte","Innate"]
["MMP15","Monocyte","Innate"]
["PNPLA6","Monocyte","Innate"]
["TMBIM6","Monocyte","Innate"]
["PQBP1","Monocyte","Innate"]
["TEX264","Monocyte","Innate"]
["IKZF1","Monocyte","Innate"]
["AKT3","Natural killer cell","Innate"]
["AXL","Natural killer cell","Innate"]
["BST2","Natural killer cell","Innate"]
["CDH2","Natural killer cell","Innate"]
["CRTAM","Natural killer cell","Innate"]
["CSF2RA","Natural killer cell","Innate"]
["CTSZ","Natural killer cell","Innate"]
["CXCL1","Natural killer cell","Innate"]
["CYTH1","Natural killer cell","Innate"]
["DAXX","Natural killer cell","Innate"]
["DGKH","Natural killer cell","Innate"]
["DLL4","Natural killer cell","Innate"]
["DPYD","Natural killer cell","Innate"]
["ERBB3","Natural killer cell","Innate"]
["F11R","Natural killer cell","Innate"]
["FAM27A","Natural killer cell","Innate"]
["FAM49A","Natural killer cell","Innate"]
["FASLG","Natural killer cell","Innate"]
["FCGR1A","Natural killer cell","Innate"]
["FN1","Natural killer cell","Innate"]
["FSTL1","Natural killer cell","Innate"]
["FUCA1","Natural killer cell","Innate"]
["GBP3","Natural killer cell","Innate"]
["GLS2","Natural killer cell","Innate"]
["GRB2","Natural killer cell","Innate"]
["LST1","Natural killer cell","Innate"]
["BCL2","Natural killer cell","Innate"]
["CDC5L","Natural killer cell","Innate"]
["FGF18","Natural killer cell","Innate"]
["FUT5","Natural killer cell","Innate"]
["FZR1","Natural killer cell","Innate"]
["GAGE2","Natural killer cell","Innate"]
["IGFBP5","Natural killer cell","Innate"]
["KANK2","Natural killer cell","Innate"]
["LDB3","Natural killer cell","Innate"]
["BTN2A2","Natural killer T cell","Innate"]
["CD101","Natural killer T cell","Innate"]
["CD109","Natural killer T cell","Innate"]
["CNPY3","Natural killer T cell","Innate"]
["CNPY4","Natural killer T cell","Innate"]
["CREB1","Natural killer T cell","Innate"]
["CRTC2","Natural killer T cell","Innate"]
["CRTC3","Natural killer T cell","Innate"]
["CSF2","Natural killer T cell","Innate"]
["KLRC1","Natural killer T cell","Innate"]
["FUT4","Natural killer T cell","Innate"]
["ICAM2","Natural killer T cell","Innate"]
["IL32","Natural killer T cell","Innate"]
["LAMP2","Natural killer T cell","Innate"]
["LILRB5","Natural killer T cell","Innate"]
["KLRG1","Natural killer T cell","Innate"]
["HSPA4","Natural killer T cell","Innate"]
["HSPB6","Natural killer T cell","Innate"]
["ISM2","Natural killer T cell","Innate"]
["ITIH2","Natural killer T cell","Innate"]
["KDM4C","Natural killer T cell","Innate"]
["KIR2DS4","Natural killer T cell","Innate"]
["KIRREL3","Natural killer T cell","Innate"]
["SDCBP","Natural killer T cell","Innate"]
["NFATC2IP","Natural killer T cell","Innate"]
["MICB","Natural killer T cell","Innate"]
["KIR2DL1","Natural killer T cell","Innate"]
["KIR2DL3","Natural killer T cell","Innate"]
["KIR3DL1","Natural killer T cell","Innate"]
["KIR3DL2","Natural killer T cell","Innate"]
["NCR1","Natural killer T cell","Innate"]
["FOSL1","Natural killer T cell","Innate"]
["TSLP","Natural killer T cell","Innate"]
["SLC7A7","Natural killer T cell","Innate"]
["SPP1","Natural killer T cell","Innate"]
["TREM2","Natural killer T cell","Innate"]
["UBASH3A","Natural killer T cell","Innate"]
["YBX2","Natural killer T cell","Innate"]
["CCDC88A","Natural killer T cell","Innate"]
["CLEC1A","Natural killer T cell","Innate"]
["THBD","Natural killer T cell","Innate"]
["PDPN","Natural killer T cell","Innate"]
["VCAM1","Natural killer T cell","Innate"]
["EMR1","Natural killer T cell","Innate"]
["CREB5","Neutrophil","Innate"]
["CDA","Neutrophil","Innate"]
["CHST15","Neutrophil","Innate"]
["S100A12","Neutrophil","Innate"]
["APOBEC3A","Neutrophil","Innate"]
["CASP5","Neutrophil","Innate"]
["MMP25","Neutrophil","Innate"]
["HAL","Neutrophil","Innate"]
["C1orf183","Neutrophil","Innate"]
["FFAR2","Neutrophil","Innate"]
["MAK","Neutrophil","Innate"]
["CXCR1","Neutrophil","Innate"]
["STEAP4","Neutrophil","Innate"]
["MGAM","Neutrophil","Innate"]
["BTNL8","Neutrophil","Innate"]
["CXCR2","Neutrophil","Innate"]
["TNFRSF10C","Neutrophil","Innate"]
["VNN3","Neutrophil","Innate"]
["CBX6","Plasmacytoid dendritic cell","Innate"]
["DAB2","Plasmacytoid dendritic cell","Innate"]
["DDX17","Plasmacytoid dendritic cell","Innate"]
["HIGD1A","Plasmacytoid dendritic cell","Innate"]
["IDH3A","Plasmacytoid dendritic cell","Innate"]
["IL3RA","Plasmacytoid dendritic cell","Innate"]
["MAGED1","Plasmacytoid dendritic cell","Innate"]
["NUCB2","Plasmacytoid dendritic cell","Innate"]
["OFD1","Plasmacytoid dendritic cell","Innate"]
["OGT","Plasmacytoid dendritic cell","Innate"]
["PDIA4","Plasmacytoid dendritic cell","Innate"]
["SERTAD2","Plasmacytoid dendritic cell","Innate"]
["SIRPA","Plasmacytoid dendritic cell","Innate"]
["TMED2","Plasmacytoid dendritic cell","Innate"]
["ENG","Plasmacytoid dendritic cell","Innate"]
["FCAR","Plasmacytoid dendritic cell","Innate"]
["IGF1","Plasmacytoid dendritic cell","Innate"]
["ITGA2B","Plasmacytoid dendritic cell","Innate"]
["GABARAP","Plasmacytoid dendritic cell","Innate"]
["GPX1","Plasmacytoid dendritic cell","Innate"]
["KRT23","Plasmacytoid dendritic cell","Innate"]
["PROK2","Plasmacytoid dendritic cell","Innate"]
["RALB","Plasmacytoid dendritic cell","Innate"]
["RETNLB","Plasmacytoid dendritic cell","Innate"]
["RNF141","Plasmacytoid dendritic cell","Innate"]
["SEC14L1","Plasmacytoid dendritic cell","Innate"]
["SEPX1","Plasmacytoid dendritic cell","Innate"]
["EMP3","Plasmacytoid dendritic cell","Innate"]
["CD300LF","Plasmacytoid dendritic cell","Innate"]
["ABTB1","Plasmacytoid dendritic cell","Innate"]
["KLHL21","Plasmacytoid dendritic cell","Innate"]
["PHRF1","Plasmacytoid dendritic cell","Innate"]

{"sheet":"Sheet3","index":2,"n_rows":24,"n_cols":33,"rows_kept":24}
["CD4_naive","CD2","CD3G","CD4","GIMAP6","GLG1","HMOX2","IL7R","ITK","LIMD2","LY9","NAA16","OBSCN","PACS1","PLCL1","RPL14","SNPH","TPP2","TRAF1","ZBTB40","CD40LG","SEPT9"]
["CD8_naive","MAN1C1","CRTAM","BLNK","CCR7","KERA","ZNF208","TREM1","CD8A","CD8B","GPR15","HTR1B","SMCP","NKTR","PSG11","SLC17A4","RRH","SMR3B","CA14","FXYD7","CCDC87","LIN28A","MOGAT2","TNKS2","GJB4","KRT1","CALY"]
["Cytotoxic","KNG1","PSORS1C2","BLNK","SCN3A","TNFRSF10C","ITGAM","KLRK1","CD8A","GNLY","GZMH","PTGDR2","CD8B","GZMA","PRF1"]
["Exhausted","ADGRG1","AFAP1L2","CCND2","CD38","CD8A","CD8B","CHST12","CTLA4","DFNB31","EOMES","FUT8","ITM2A","LAG3","MYO1E","NDFIP2","PARK7","PDCD1","SIRPG","SNX9"]
["Tr1","TNFRSF4","CD4","CCR4","CD28","LAX1"]
["nTreg","FOXP3","STAT5A","DUSP4","CD4","CTLA4","TNFRSF9","IL10RA","IL2RA","CD5","SIT1"]
["iTreg","FOXP3","STAT5A","CCR8","CD5","HS3ST3B1","TTN","CTLA4","FASLG","ICOS","CCR3","GALNT8","NFATC3","SIT1","CD28","IL10RA","PPM1B","ATG2B","CCR4","ZFYVE9"]
["Th1","IFNG","IL2","MNAT1","SLAMF1","STAT1","EIF2B2","APBB2","CCL4","CTLA4","GGT1","LTA","SYNGR3","TACO1"]
["Th2","GZMK","IL4","GATA3","GSTA4","SLC25A44"]
["Th17","IL1R1","RORC","CD4","IL21","IL17RA"]
["Tfh","CA8","CD2","CD3G","GZMM","ITK","KLRB1","LTA","MAP4K1","ST8SIA1","TRAC","TRAV9-2","TRIB2","UBASH3A"]
["Central_memory","CORO7","ATM","GMEB2","SNRPN","ADSL","ITK","TFAP4","NAA16","LY9","CYLD","GIMAP4","PURA","DVL1","RPP38","LRIG2","IL7R","CDKN2AIP","APBB1","IPCEF1","CD247","CD40LG","TRADD","CD3E","TPR","ARID5B","UBASH3A","NCK1","SPTAN1","GPR171","CD5"]
["Effector_memory","APBA3","CD160","CD2","CD8B","CDK10","CDKN2AIP","CHST12","COG4","CX3CR1","DHX16","EWSR1","GIMAP6","GPR171","GZMK","HMOX2","IKZF3","ITK","KLRD1","KLRG1","MAPKAPK5","MORC2","MRFAP1L1","PLCG1","PSMC5","RNF167","SBF1","SF3B2","SLAMF1","TBCD","USP47","ZFYVE9","ZNF549"]
["NKT","CASP5","DOLK","GMIP","PRR5L","SGCA","SLAMF1","TCOF1","TGFBR2"]
["MAIT","CD8A","CD8B","CERK","FLT4","TBC1D31","DKK3","GPR171","NR1D1","SLAMF1","TC2N"]
["DC","BLVRB","C1QA","C1QB","CSF1R","CXCR3","FGL2","GZMB","IL21R","KCNA5","KCNC3","KCTD5","LILRB4","LMAN2L","NFKB1","PLD2","PTCRA","PTGIR","SIGLEC1","SLAMF8","SLC15A3","SYT17","VAV2","CA8","CALY","CRTAM","CYP4F3","GATA3","ITIH4","PRR5L","ST8SIA1","TNFRSF10C"]
["Bcell","AFTPH","AHSP","ANXA3","CNOT1","HLA-DPB1","HLA-DQA1","LSM6","MEFV","MS4A1","NMUR1","PADI4","PYGM","STRN4","TRAF3","TCL6","BLK","WNT16","CD37","CD19","HRH4","CA1","COL19A1","GNG3","PLIN1","SGCA","CD79A","CD79B"]
["Monocyte","IL7R","APOC3","ADCY8","CLCA4","CPA2","DPP6","HSPB6","KNG1","KLRK1","GZMH","KLRB1","SGCA","CA1","TLR8","CYBB","IGSF6","KLRF1","CYP4F3","CLEC10A","FOLR2","LTBR","MAP3K2","NUP214","OSBPL11","RTN3","SERP1","TBK1","SOCS3"]
["Macrophage","ARPC4","ATP6V0E1","BPI","C1QA","C1QB","CAMP","CHIT1","CLEC5A","CLIP1","CSF1R","CYBB","FGR","GGA1","GRB2","IFNAR1","IGSF6","IL17RA","LILRA2","MARCO","MMP8","MS4A6A","OTUD4","PSME1","RENBP"]
["NK","DNAJB14","IL18RAP","IL2RB","KIR2DL3","KIR3DL2","NCR1","NCR3","PSMD4","SPON2","XCL1","C1QB","CALY","CD37","CLEC10A","CRTAM","CSF2RB","CX3CR1","GZMB","IL7R","KNG1","MAN1C1","PRR5L","SYT17"]
["Neutrophil","IL18RAP","BMX","BTNL8","CASP5","CLC","CXCR1","CXCR2","FCGR3B","FPR2","HSPA6","MEFV","PADI4","S100A12","TREML2","TRPM6","SIGLEC5","CREB5","ALPL","AATK","CEACAM3","CSF2RB","CSF3R","FBXO38","MAK","PAK2","TOP1","UBXN2B","VNN3"]
["Gamma_delta","KLRG1","CYP4A11","CCR5","GZMH","ACD","CHST12","GZMA","GZMB","LAG3","NKG7","PRF1","PVRIG","TINF2","ZMAT5","C1orf61","GNLY","LCP2","PSTPIP1","PTPN4","RALY","TAB2","TDP1"]
["CD4_T","SELL","NT5E","ITK","TRMT2B","AAK1","CD4","GPR183","KLHL3","CCR4","ITIH4","DLEC1","ZAP70","PLXDC1","CD40LG","LAX1","TNFRSF4","GPR171","LY9","NCK2","PLCG1"]
["CD8_T","CD27","CD8B","CLUAP1","CRTAM","FKTN","KLRG1","LY9","PLCG1","RING1","SF1","SIRPG","TSPAN32","ARHGEF1","EEF1D","PPP1R2","CTSW","FBXW4","ZNF611","GZMH","CD8A","TTN","CD7","CX3CR1"]

{"sheet":"Sheet4","index":3,"n_rows":18,"n_cols":2,"rows_kept":18}
[]
["TIS score","CCL5"]
[null,"CD27"]
[null,"CD274"]
[null,"CD276"]
[null,"CD8A"]
[null,"CMKLR1"]
[null,"CXCL9"]
[null,"HLA-DQA1"]
[null,"HLA-DRB1"]
[null,"HLA-E"]
[null,"IDO1"]
[null,"LAG3"]
[null,"NKG7"]
[null,"PDCD1LG2"]
[null,"PSMB10"]
[null,"STAT1"]
[null,"TIGIT"]

{"sheet":"Sheet5","index":4,"n_rows":576,"n_cols":12,"rows_kept":576}
[null,"setID","name","nAnno","nLead","peak","total","es","nes","pvalue","adjp","distance"]
[1,"REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM","Cytokine Signaling in Immune system",223,121,3388,18403,0.561,2.19,{"v":0.0005,"d":"5.00E-04"},0.005]
[2,"REACTOME_METABOLISM_OF_MRNA","Metabolism of mRNA",195,144,6225,18403,0.482,1.87,{"v":0.0005,"d":"5.00E-04"},0.005]
[3,"REACTOME_METABOLISM_OF_RNA","Metabolism of RNA",237,169,6225,18403,0.466,1.82,{"v":0.0005,"d":"5.00E-04"},0.005]
[4,"REACTOME_HEMOSTASIS","Hemostasis",351,135,3143,18403,0.446,1.77,{"v":0.0005,"d":"5.00E-04"},0.005]
[5,"REACTOME_METABOLISM_OF_PROTEINS","Metabolism of proteins",382,235,6043,18403,0.414,1.65,{"v":0.0005,"d":"5.00E-04"},0.005]
[6,"REACTOME_CELL_CYCLE_MITOTIC","Cell Cycle, Mitotic",270,179,7265,18403,0.394,1.55,{"v":0.0005,"d":"5.00E-04"},0.005]
[7,"REACTOME_INNATE_IMMUNE_SYSTEM","Innate Immune System",185,110,4199,18403,0.561,2.17,{"v":0.0005,"d":"5.00E-04"},0.005]
[8,"REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION","Class I MHC mediated antigen processing and presentation",198,102,4845,18403,0.449,1.74,{"v":0.0005,"d":"5.00E-04"},0.005]
[9,"REACTOME_DNA_REPLICATION","DNA Replication",169,119,7249,18403,0.417,1.6,{"v":0.0005,"d":"5.00E-04"},0.005]
[10,"REACTOME_HIV_INFECTION","HIV Infection",179,102,6224,18403,0.389,1.5,{"v":0.0005,"d":"5.00E-04"},0.005]
[11,"REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION","Platelet activation, signaling and aggregation",158,77,3110,18403,0.545,2.09,{"v":0.0005,"d":"5.00E-04"},0.005]
[12,"REACTOME_INTERFERON_SIGNALING","Interferon Signaling",134,78,3388,18403,0.593,2.25,{"v":0.0005,"d":"5.00E-04"},0.005]
[13,"REACTOME_TRANSLATION","Translation",144,114,6384,18403,0.503,1.92,{"v":0.0005,"d":"5.00E-04"},0.005]
[14,"REACTOME_INFLUENZA_LIFE_CYCLE","Influenza Life Cycle",131,99,6191,18403,0.485,1.84,{"v":0.0005,"d":"5.00E-04"},0.005]
[15,"REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS","Host Interactions of HIV factors",112,73,6314,18403,0.445,1.67,{"v":0.0005,"d":"5.00E-04"},0.005]
[16,"REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS","Peptide ligand-binding receptors",123,33,2113,18403,0.456,1.72,{"v":0.0005,"d":"5.00E-04"},0.005]
[17,"REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE","SRP-dependent cotranslational protein targeting to membrane",107,91,6043,18403,0.552,2.06,{"v":0.0005,"d":"5.00E-04"},0.005]
[18,"REACTOME_APOPTOSIS","Apoptosis",125,65,4742,18403,0.433,1.64,{"v":0.0005,"d":"5.00E-04"},0.005]
[19,"REACTOME_3_UTR_MEDIATED_TRANSLATIONAL_REGULATION","3' -UTR-mediated translational regulation",104,85,6366,18403,0.511,1.9,{"v":0.0005,"d":"5.00E-04"},0.005]
[20,"REACTOME_CELL_CYCLE_CHECKPOINTS","Cell Cycle Checkpoints",105,68,5593,18403,0.457,1.7,{"v":0.0005,"d":"5.00E-04"},0.005]
[21,"REACTOME_TOLL_RECEPTOR_CASCADES","Toll Receptor Cascades",103,57,4199,18403,0.513,1.91,{"v":0.0005,"d":"5.00E-04"},0.005]
[22,"REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX","Nonsense Mediated Decay Enhanced by the Exon Junction Complex",102,81,6100,18403,0.51,1.9,{"v":0.0005,"d":"5.00E-04"},0.005]
[23,"REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION","Influenza Viral RNA Transcription and Replication",99,81,6043,18403,0.531,1.97,{"v":0.0005,"d":"5.00E-04"},0.005]
[24,"REACTOME_SIGNALING_BY_ILS","Signaling by Interleukins",90,63,5615,18403,0.527,1.94,{"v":0.0005,"d":"5.00E-04"},0.005]
[25,"REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION","MHC class II antigen presentation",80,23,1671,18403,0.477,1.74,{"v":0.0005,"d":"5.00E-04"},0.005]
[26,"REACTOME_PEPTIDE_CHAIN_ELONGATION","Peptide chain elongation",83,70,6043,18403,0.542,1.98,0.00051,0.005]
[27,"REACTOME_REGULATION_OF_MRNA_STABILITY_BY_PROTEINS_THAT_BIND_AU_RICH_ELEMENTS","Regulation of mRNA Stability by Proteins that Bind AU-rich Elements",74,44,4742,18403,0.479,1.74,0.00051,0.005]
[28,"REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL","Cell surface interactions at the vascular wall",73,39,3066,18403,0.597,2.16,0.00051,0.005]
[29,"REACTOME_REGULATION_OF_MITOTIC_CELL_CYCLE","Regulation of mitotic cell cycle",71,48,4806,18403,0.517,1.86,0.00051,0.005]
[30,"REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION","Extracellular matrix organization",67,40,3138,18403,0.649,2.33,0.00051,0.005]
[31,"REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS","Integrin cell surface interactions",65,29,1345,18403,0.643,2.3,0.00051,0.005]
[32,"REACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION","Antigen processing-Cross presentation",65,52,4572,18403,0.641,2.3,0.00051,0.005]
[33,"REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_","Response to elevated platelet cytosolic Ca2+",64,35,1857,18403,0.644,2.3,0.00051,0.005]
[34,"REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1","APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1",60,40,4635,18403,0.522,1.85,0.00051,0.005]
[35,"REACTOME_APC_C_CDC20_MEDIATED_DEGRADATION_OF_MITOTIC_PROTEINS","APC/C:Cdc20 mediated degradation of mitotic proteins",61,40,4635,18403,0.513,1.82,0.00051,0.005]
[36,"REACTOME_ORC1_REMOVAL_FROM_CHROMATIN","Orc1 removal from chromatin",61,38,4572,18403,0.504,1.79,0.00051,0.005]
[37,"REACTOME_INTERFERON_GAMMA_SIGNALING","Interferon gamma signaling",58,41,1830,18403,0.762,2.69,0.00051,0.005]
[38,"REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY","Costimulation by the CD28 family",58,19,1609,18403,0.529,1.87,0.00051,0.005]
[39,"REACTOME_ACTIVATION_OF_NF_KAPPAB_IN_B_CELLS","Activation of NF-kappaB in B Cells",56,38,4602,18403,0.514,1.81,0.00051,0.005]
[40,"REACTOME_RIG_I_MDA5_MEDIATED_INDUCTION_OF_IFN_ALPHA_BETA_PATHWAYS","RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways",55,34,4141,18403,0.54,1.89,0.00051,0.005]
[41,"REACTOME_CYCLIN_E_ASSOCIATED_EVENTS_DURING_G1_S_TRANSITION_","Cyclin E associated events during G1/S transition ",57,37,4572,18403,0.524,1.85,0.00051,0.005]
[42,"REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S","Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S",57,46,6282,18403,0.516,1.82,0.00051,0.005]
[43,"REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL","Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell",51,23,1022,18403,0.696,2.42,0.00051,0.005]
[44,"REACTOME_ER_PHAGOSOME_PATHWAY","ER-Phagosome pathway",53,41,4572,18403,0.619,2.17,0.00051,0.005]
[45,"REACTOME_SEMAPHORIN_INTERACTIONS","Semaphorin interactions",53,21,1974,18403,0.543,1.9,0.00051,0.005]
[46,"REACTOME_INTERFERON_ALPHA_BETA_SIGNALING","Interferon alpha/beta signaling",49,34,1787,18403,0.744,2.57,0.00052,0.005]
[47,"REACTOME_COLLAGEN_FORMATION","Collagen formation",49,33,3138,18403,0.698,2.41,0.00052,0.005]
[48,"REACTOME_P53_DEPENDENT_G1_DNA_DAMAGE_RESPONSE","p53-Dependent G1 DNA Damage Response",49,34,4572,18403,0.555,1.92,0.00052,0.005]
[49,"REACTOME_SCFSKP2_MEDIATED_DEGRADATION_OF_P27_P21","SCF(Skp2)-mediated degradation of p27/p21",49,34,4572,18403,0.553,1.91,0.00052,0.005]
[50,"REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES","Chemokine receptors bind chemokines",47,19,2330,18403,0.587,2.02,0.00052,0.005]
[51,"REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0","Destabilization of mRNA by AUF1 (hnRNP D0)",47,35,4721,18403,0.576,1.98,0.00052,0.005]
[52,"REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G","Vif-mediated degradation of APOBEC3G",44,32,4572,18403,0.577,1.96,0.00052,0.005]
[53,"REACTOME_SCF_BETA_TRCP_MEDIATED_DEGRADATION_OF_EMI1","SCF-beta-TrCP mediated degradation of Emi1",45,34,4806,18403,0.572,1.95,0.00052,0.005]
[54,"REACTOME_CDK_MEDIATED_PHOSPHORYLATION_AND_REMOVAL_OF_CDC6","CDK-mediated phosphorylation and removal of Cdc6",43,32,4572,18403,0.58,1.97,0.00052,0.005]
[55,"REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES","Cross-presentation of soluble exogenous antigens (endosomes)",43,31,4572,18403,0.578,1.96,0.00052,0.005]
[56,"REACTOME_AUTODEGRADATION_OF_THE_E3_UBIQUITIN_LIGASE_COP1","Autodegradation of the E3 ubiquitin ligase COP1",43,31,4572,18403,0.566,1.92,0.00052,0.005]
[57,"REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES","Generation of second messenger molecules",25,12,878,18403,0.686,2.13,0.00054,0.005]
[58,"REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING","Sema4D in semaphorin signaling",22,13,1974,18403,0.654,1.98,0.00055,0.005]
[59,"REACTOME_SMOOTH_MUSCLE_CONTRACTION","Smooth Muscle Contraction",21,13,1852,18403,0.676,2.03,0.00055,0.005]
[60,"REACTOME_COMPLEMENT_CASCADE","Complement cascade",19,11,703,18403,0.819,2.41,0.00056,0.005]
[61,"REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC","Antigen Presentation: Folding, assembly and peptide loading of class I MHC",19,15,3940,18403,0.697,2.05,0.00056,0.005]
[62,"REACTOME_PD1_SIGNALING","PD-1 signaling",17,12,1609,18403,0.767,2.19,0.00056,0.005]
[63,"REACTOME_FORMATION_OF_FIBRIN_CLOT_CLOTTING_CASCADE","Formation of Fibrin Clot (Clotting Cascade)",17,7,903,18403,0.677,1.94,0.00056,0.005]
[64,"REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING","Growth hormone receptor signaling",16,9,1746,18403,0.677,1.91,0.00057,0.005]
[65,"REACTOME_PHOSPHORYLATION_OF_CD3_AND_TCR_ZETA_CHAINS","Phosphorylation of CD3 and TCR zeta chains",15,9,740,18403,0.77,2.12,5.8E-4,0.005]
[66,"REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE","Translocation of ZAP-70 to Immunological synapse",13,9,1567,18403,0.768,2.05,5.8E-4,0.005]
[67,"REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR","Trafficking and processing of endosomal TLR",11,9,1660,18403,0.797,2.03,{"v":0.0006,"d":"6.00E-04"},0.005]
[68,"REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS","Caspase-mediated cleavage of cytoskeletal proteins",11,6,1307,18403,0.755,1.93,{"v":0.0006,"d":"6.00E-04"},0.005]
[69,"REACTOME_REGULATION_OF_COMPLEMENT_CASCADE","Regulation of Complement cascade",10,6,703,18403,0.791,1.98,{"v":0.0006,"d":"6.00E-04"},0.005]
[70,"REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION","Antigen processing: Ubiquitination and Proteasome degradation",164,108,7497,18403,0.384,1.47,1E-3,0.0078]
[71,"REACTOME_G_ALPHA_I_SIGNALLING_EVENTS","G alpha (i) signalling events",134,34,1935,18403,0.42,1.6,1E-3,0.0078]
[72,"REACTOME_MITOTIC_M_M_G1_PHASES","Mitotic M-M/G1 phases",150,104,7249,18403,0.409,1.56,1E-3,0.0078]
[73,"REACTOME_MITOTIC_G1_G1_S_PHASES","Mitotic G1-G1/S phases",120,85,7215,18403,0.427,1.61,1E-3,0.0078]
[74,"REACTOME_S_PHASE","S Phase",99,75,7215,18403,0.449,1.66,1E-3,0.0078]
[75,"REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX","Formation of the ternary complex, and subsequently, the 43S complex",50,40,6203,18403,0.518,1.8,1E-3,0.0078]
[76,"REACTOME_P53_INDEPENDENT_G1_S_DNA_DAMAGE_CHECKPOINT","p53-Independent G1/S DNA damage checkpoint",44,31,4572,18403,0.554,1.89,1E-3,0.0078]
[77,"REACTOME_NCAM1_INTERACTIONS","NCAM1 interactions",29,11,1177,18403,0.636,2.03,0.0011,0.0078]
[78,"REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE","GPVI-mediated activation cascade",29,14,1796,18403,0.63,2.01,0.0011,0.0078]
[79,"REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE","Sema4D induced cell migration and growth-cone collapse",18,10,1539,18403,0.66,1.91,0.0011,0.0082]
[80,"REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS","Cell-extracellular matrix interactions",13,11,2982,18403,0.747,2,0.0012,0.0083]
[81,"REACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTERGRINS_","GRB2:SOS provides linkage to MAPK signaling for Intergrins ",10,5,1181,18403,0.707,1.77,0.0012,0.0085]
[82,"REACTOME_SIGNALING_BY_THE_B_CELL_RECEPTOR_BCR","Signaling by the B Cell Receptor (BCR)",111,71,6206,18403,0.424,1.59,1.5E-3,0.0099]
[83,"REACTOME_MRNA_SPLICING","mRNA Splicing",102,68,6389,18403,0.432,1.61,1.5E-3,0.0099]
[84,"REACTOME_G1_S_TRANSITION","G1/S Transition",98,73,7215,18403,0.444,1.65,1.5E-3,0.0099]
[85,"REACTOME_ACTIVATED_TLR4_SIGNALLING","Activated TLR4 signalling",82,43,4602,18403,0.462,1.69,1.5E-3,0.0099]
[86,"REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS_","Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.",79,53,5678,18403,0.468,1.71,1.5E-3,0.0099]
[87,"REACTOME_AUTODEGRADATION_OF_CDH1_BY_CDH1_APC_C","Autodegradation of Cdh1 by Cdh1:APC/C",53,34,4635,18403,0.503,1.76,1.5E-3,0.0099]
[88,"REACTOME_CDT1_ASSOCIATION_WITH_THE_CDC6_ORC_ORIGIN_COMPLEX","CDT1 association with the CDC6:ORC:origin complex",51,32,4572,18403,0.502,1.75,1.5E-3,0.0099]
[89,"REACTOME_TCR_SIGNALING","TCR signaling",47,20,2639,18403,0.535,1.84,0.0016,0.0099]
[90,"REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC","Regulation of ornithine decarboxylase (ODC)",45,31,4572,18403,0.548,1.87,0.0016,0.0099]
[91,"REACTOME_IRON_UPTAKE_AND_TRANSPORT","Iron uptake and transport",32,13,3101,18403,0.559,1.82,0.0016,0.0099]
[92,"REACTOME_DOWNSTREAM_TCR_SIGNALING","Downstream TCR signaling",31,14,2536,18403,0.57,1.84,0.0016,0.0099]
[93,"REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS","Latent infection of Homo sapiens with Mycobacterium tuberculosis",29,13,3202,18403,0.598,1.91,0.0016,0.0099]
[94,"REACTOME_ACTIVATION_OF_IRF3_IRF7_MEDIATED_BY_TBK1_IKK_EPSILON","Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon",13,11,4048,18403,0.698,1.86,0.0017,0.011]
[95,"REACTOME_SYNTHESIS_OF_DNA","Synthesis of DNA",85,65,7193,18403,0.454,1.67,2E-3,0.012]
[96,"REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION","Asparagine N-linked glycosylation",74,49,5525,18403,0.457,1.66,2E-3,0.012]
[97,"REACTOME_M_G1_TRANSITION","M/G1 Transition",73,43,4791,18403,0.459,1.66,2E-3,0.012]
[98,"REACTOME_REGULATION_OF_APOPTOSIS","Regulation of Apoptosis",51,32,4572,18403,0.49,1.71,0.0021,0.012]
[99,"REACTOME_ACYL_CHAIN_REMODELLING_OF_PE","Acyl chain remodelling of PE",13,10,4826,18403,0.665,1.78,2.3E-3,0.013]
[100,"REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS","Extrinsic Pathway for Apoptosis",13,10,3666,18403,0.663,1.77,2.3E-3,0.013]
[101,"REACTOME_OTHER_SEMAPHORIN_INTERACTIONS","Other semaphorin interactions",13,5,1712,18403,0.659,1.76,2.3E-3,0.013]
[102,"REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS","Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)",11,5,779,18403,0.697,1.78,0.0024,0.014]
[103,"REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS","Class A/1 (Rhodopsin-like receptors)",199,42,1995,18403,0.369,1.43,0.0025,0.014]
[104,"REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION","Post-translational protein modification",149,88,5928,18403,0.397,1.52,0.0025,0.014]
[105,"REACTOME_TCA_CYCLE_AND_RESPIRATORY_ELECTRON_TRANSPORT","The citric acid (TCA) cycle and respiratory electron transport",110,64,5718,18403,0.419,1.57,0.0025,0.014]
[106,"REACTOME_RESPIRATORY_ELECTRON_TRANSPORT","Respiratory electron transport",63,43,5678,18403,0.465,1.66,0.0025,0.014]
[107,"REACTOME_MUSCLE_CONTRACTION","Muscle contraction",34,16,1852,18403,0.556,1.83,0.0026,0.014]
[108,"REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING","Negative regulators of RIG-I/MDA5 signaling",29,19,4141,18403,0.584,1.86,0.0027,0.014]
[109,"REACTOME_LIPID_DIGESTION_MOBILIZATION_AND_TRANSPORT","Lipid digestion, mobilization, and transport",29,16,3755,18403,0.574,1.83,0.0027,0.014]
[110,"REACTOME_AMINE_DERIVED_HORMONES","Amine-derived hormones",10,11,17344,18403,-0.751,-2.55,0.0029,0.015]
[111,"REACTOME_REGULATION_OF_IFNG_SIGNALING","Regulation of IFNG signaling",12,10,3866,18403,0.689,1.8,0.003,0.015]
[112,"REACTOME_SEROTONIN_RECEPTORS","Serotonin receptors",11,9,18185,18403,-0.775,-2.78,0.003,0.015]
[113,"REACTOME_GABA_A_RECEPTOR_ACTIVATION","GABA A receptor activation",11,12,18384,18403,-0.905,-3.24,0.003,0.015]
[114,"REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE","Dopamine Neurotransmitter Release Cycle",11,10,18371,18403,-0.92,-3.29,0.003,0.015]
[115,"REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY","TRAF3-dependent IRF activation pathway",11,8,3898,18403,0.675,1.72,0.003,0.015]
[116,"REACTOME_REGULATION_OF_IFNA_SIGNALING","Regulation of IFNA signaling",11,11,5429,18403,0.666,1.7,0.003,0.015]
[117,"REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA","Processing of Capped Intron-Containing Pre-mRNA",129,82,6389,18403,0.405,1.53,0.003,0.015]
[118,"REACTOME_DIABETES_PATHWAYS","Diabetes pathways",108,53,4941,18403,0.414,1.55,0.003,0.015]
[119,"REACTOME_ACYL_CHAIN_REMODELLING_OF_PI","Acyl chain remodelling of PI",10,5,1672,18403,0.688,1.72,0.003,0.015]
[120,"REACTOME_ASSEMBLY_OF_THE_PRE_REPLICATIVE_COMPLEX","Assembly of the pre-replicative complex",60,35,4572,18403,0.465,1.65,0.0031,0.015]
[121,"REACTOME_SIGNALING_BY_WNT","Signaling by Wnt",58,33,4572,18403,0.47,1.66,0.0031,0.015]
[122,"REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE","Glutamate Neurotransmitter Release Cycle",13,11,18371,18403,-0.86,-3.26,0.0035,0.017]
[123,"REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION","Unblocking of NMDA receptor, glutamate binding and activation",14,11,18402,18403,-0.785,-3.08,0.0036,0.017]
[124,"REACTOME_IL_3_5_AND_GM_CSF_SIGNALING","Interleukin-3, 5 and GM-CSF signaling",34,18,3866,18403,0.539,1.77,0.0037,0.017]
[125,"REACTOME_PLATELET_CALCIUM_HOMEOSTASIS","Platelet calcium homeostasis",15,7,18345,18403,-0.526,-2.14,3.8E-3,0.017]
[126,"REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII","CREB phosphorylation through the activation of CaMKII",15,8,18402,18403,-0.657,-2.67,3.8E-3,0.017]
[127,"REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION","GABA synthesis, release, reuptake and degradation",15,14,18371,18403,-0.893,-3.63,3.8E-3,0.017]
[128,"REACTOME_GLUTATHIONE_CONJUGATION","Glutathione conjugation",14,11,4261,18403,0.641,1.74,0.0041,0.018]
[129,"REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR","Ras activation uopn Ca2+ infux through NMDA receptor",17,9,18402,18403,-0.656,-2.73,0.0044,0.019]
[130,"REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS","Interaction between L1 and Ankyrins",17,12,18362,18403,-0.777,-3.23,0.0044,0.019]
[131,"REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT","Ligand-gated ion channel transport",17,16,18384,18403,-0.865,-3.6,0.0044,0.019]
[132,"REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION","TRAF6 mediated IRF7 activation",15,11,3898,18403,0.633,1.74,0.0046,0.02]
[133,"REACTOME_KERATAN_SULFATE_KERATIN_METABOLISM","Keratan sulfate/keratin metabolism",24,12,2937,18403,0.573,1.76,0.0049,0.021]
[134,"REACTOME_LIPOPROTEIN_METABOLISM","Lipoprotein metabolism",19,10,3139,18403,0.587,1.73,0.005,0.021]
[135,"REACTOME_MYD88_MAL_CASCADE_INITIATED_ON_PLASMA_MEMBRANE","MyD88:Mal cascade initiated on plasma membrane",72,52,7380,18403,0.435,1.57,0.0051,0.021]
[136,"REACTOME_TRIF_MEDIATED_TLR3_SIGNALING","TRIF mediated TLR3 signaling",66,48,7141,18403,0.445,1.59,0.0051,0.021]
[137,"REACTOME_MRNA_PROCESSING","mRNA Processing",145,87,6389,18403,0.382,1.46,0.0055,0.023]
[138,"REACTOME_NFKB_AND_MAP_KINASES_ACTIVATION_MEDIATED_BY_TLR4_SIGNALING_REPERTOIRE","NFkB and MAP kinases activation mediated by TLR4 signaling repertoire",64,46,7141,18403,0.447,1.6,0.0056,0.023]
[139,"REACTOME_ACYL_CHAIN_REMODELLING_OF_PC","Acyl chain remodelling of PC",14,10,4826,18403,0.628,1.7,0.0058,0.024]
[140,"REACTOME_IL1_SIGNALING","Interleukin-1 signaling",34,25,5594,18403,0.522,1.72,0.0058,0.024]
[141,"REACTOME_IL_2_SIGNALING","Interleukin-2 signaling",32,14,2613,18403,0.514,1.67,0.0058,0.024]
[142,"REACTOME_GLYCOSAMINOGLYCAN_METABOLISM","Glycosaminoglycan metabolism",94,34,3183,18403,0.411,1.52,0.006,0.024]
[143,"REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS","Trafficking of AMPA receptors",24,13,18367,18403,-0.605,-2.81,6.3E-3,0.025]
[144,"REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_RAS","CREB phosphorylation through the activation of Ras",25,9,18402,18403,-0.453,-2.12,0.0065,0.026]
[145,"REACTOME_AMINE_LIGAND_BINDING_RECEPTORS","Amine ligand-binding receptors",25,18,18392,18403,-0.653,-3.06,0.0065,0.026]
[146,"REACTOME_NEUROTRANSMITTER_RELEASE_CYCLE","Neurotransmitter Release Cycle",26,21,18371,18403,-0.859,-4.1,6.6E-3,0.026]
[147,"REACTOME_METABOLISM_OF_CARBOHYDRATES","Metabolism of carbohydrates",195,120,7590,18403,0.353,1.37,0.007,0.027]
[148,"REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS","Trafficking of GluR2-containing AMPA receptors",13,7,18274,18403,-0.555,-2.1,0.0071,0.028]
[149,"REACTOME_PACKAGING_OF_TELOMERE_ENDS","Packaging Of Telomere Ends",31,21,18391,18403,-0.663,-3.33,0.0082,0.032]
[150,"REACTOME_POST_NMDA_RECEPTOR_ACTIVATION_EVENTS","Post NMDA receptor activation events",30,13,18402,18403,-0.476,-2.37,0.0085,0.033]
[151,"REACTOME_TRAF6_MEDIATED_INDUCTION_OF_TAK1_COMPLEX","TRAF6 mediated induction of TAK1 complex",12,11,5480,18403,0.627,1.64,0.0089,0.034]
[152,"REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX","Degradation of the extracellular matrix",18,6,1355,18403,0.57,1.65,0.009,0.034]
[153,"REACTOME_CELL_CYCLE","Cell Cycle",334,209,7265,18403,0.325,1.29,0.009,0.034]
[154,"REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES","Antiviral mechanism by IFN-stimulated genes",60,43,6854,18403,0.438,1.55,0.0092,0.034]
[155,"REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS","Voltage gated Potassium channels",34,29,18355,18403,-0.747,-3.8,0.0094,0.035]
[156,"REACTOME_ACTIVATION_OF_NMDA_RECEPTOR_UPON_GLUTAMATE_BINDING_AND_POSTSYNAPTIC_EVENTS","Activation of NMDA receptor upon glutamate binding and postsynaptic events",33,16,18402,18403,-0.515,-2.57,0.0095,0.035]
[157,"REACTOME_DOWNSTREAM_SIGNALING_EVENTS_OF_B_CELL_RECEPTOR_BCR","Downstream Signaling Events Of B Cell Receptor (BCR)",83,54,6206,18403,0.417,1.53,0.0096,0.035]
[158,"REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS","Synthesis of bile acids and bile salts",11,6,2586,18403,0.638,1.63,0.0096,0.035]
[159,"REACTOME_RNA_POL_I_PROMOTER_OPENING","RNA Polymerase I Promoter Opening",35,23,18391,18403,-0.685,-3.56,0.0098,0.035]
[160,"REACTOME_AXON_GUIDANCE","Axon guidance",196,52,2685,18403,0.347,1.34,0.01,0.036]
[161,"REACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM","Bile acid and bile salt metabolism",14,7,2586,18403,0.603,1.64,0.01,0.037]
[162,"REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING","Advanced glycosylation endproduct receptor signaling",11,7,3396,18403,0.634,1.62,0.011,0.038]
[163,"REACTOME_IL_6_SIGNALING","Interleukin-6 signaling",10,9,5080,18403,0.649,1.63,0.011,0.038]
[164,"REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION","Hyaluronan uptake and degradation",10,7,4341,18403,0.649,1.62,0.011,0.038]
[165,"REACTOME_SIGNALING_BY_PDGF","Signaling by PDGF",94,28,2645,18403,0.397,1.47,0.011,0.038]
[166,"REACTOME_CELL_CELL_COMMUNICATION","Cell-Cell communication",91,34,3709,18403,0.405,1.49,0.011,0.038]
[167,"REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION","YAP1- and WWTR1 (TAZ)-stimulated gene expression",19,7,1908,18403,0.554,1.63,0.012,0.04]
[168,"REACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS","TGF-beta receptor signaling activates SMADs",19,13,4687,18403,0.553,1.63,0.012,0.04]
[169,"REACTOME_INTEGRIN_ALPHAIIB_BETA3_SIGNALING","Integrin alphaIIb beta3 signaling",19,7,1282,18403,0.552,1.62,0.012,0.04]
[170,"REACTOME_SIGNAL_AMPLIFICATION","Signal amplification",25,12,3024,18403,0.516,1.6,0.012,0.04]
[171,"REACTOME_GABA_RECEPTOR_ACTIVATION","GABA receptor activation",41,24,18384,18403,-0.488,-2.68,0.012,0.04]
[172,"REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING","Downregulation of TGF-beta receptor signaling",17,11,4048,18403,0.573,1.64,0.012,0.041]
[173,"REACTOME_AMYLOIDS","Amyloids",45,24,18391,18403,-0.398,-2.22,0.013,0.042]
[174,"REACTOME_ION_CHANNEL_TRANSPORT","Ion channel transport",45,24,18384,18403,-0.553,-3.1,0.013,0.042]
[175,"REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS","Metabolism of lipids and lipoproteins",348,169,6626,18403,0.32,1.27,0.013,0.043]
[176,"REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE","Deposition of New CENPA-containing Nucleosomes at the Centromere",44,18,18391,18403,-0.437,-2.4,0.013,0.043]
[177,"REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION","TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)",11,6,2030,18403,0.626,1.6,0.014,0.045]
[178,"REACTOME_REGULATION_OF_SIGNALING_BY_CBL","Regulation of signaling by CBL",15,5,680,18403,0.594,1.64,0.014,0.045]
[179,"REACTOME_GPCR_LIGAND_BINDING","GPCR ligand binding",267,59,2553,18403,0.328,1.29,0.014,0.045]
[180,"REACTOME_MEIOTIC_SYNAPSIS","Meiotic Synapsis",48,18,18391,18403,-0.482,-2.73,0.014,0.045]
[181,"REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH","NCAM signaling for neurite out-growth",50,11,1177,18403,0.445,1.54,0.014,0.046]
[182,"REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS","Na+/Cl- dependent neurotransmitter transporters",10,5,18206,18403,-0.544,-1.84,0.015,0.046]
[183,"REACTOME_NUCLEOTIDE_BINDING_DOMAIN_LEUCINE_RICH_REPEAT_CONTAINING_RECEPTOR_NLR_SIGNALING_PATHWAYS","Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways",41,26,5670,18403,0.463,1.56,0.015,0.046]
[184,"REACTOME_TRAF6_MEDIATED_INDUCTION_OF_NFKB_AND_MAP_KINASES_UPON_TLR7_8_OR_9_ACTIVATION","TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation",65,46,7380,18403,0.417,1.49,0.015,0.046]
[185,"REACTOME_METABOLISM_OF_NUCLEOTIDES","Metabolism of nucleotides",65,47,7581,18403,0.416,1.49,0.015,0.046]
[186,"REACTOME_MRNA_SPLICING_MINOR_PATHWAY","mRNA Splicing - Minor Pathway",38,26,5854,18403,0.469,1.57,0.015,0.047]
[187,"REACTOME_MEIOTIC_RECOMBINATION","Meiotic Recombination",52,23,18391,18403,-0.481,-2.77,0.015,0.047]
[188,"REACTOME_HYALURONAN_METABOLISM","Hyaluronan metabolism",13,6,2018,18403,0.606,1.62,0.017,0.051]
[189,"REACTOME_IL_RECEPTOR_SHC_SIGNALING","Interleukin receptor SHC signaling",20,11,3866,18403,0.541,1.61,0.017,0.052]
[190,"REACTOME_RNA_POL_I_TRANSCRIPTION","RNA Polymerase I Transcription",57,23,18391,18403,-0.494,-2.86,0.017,0.052]
[191,"REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION","Nef mediated downregulation of MHC class I complex cell surface expression",10,3,770,18403,0.634,1.59,0.017,0.052]
[192,"REACTOME_TELOMERE_MAINTENANCE","Telomere Maintenance",56,17,18391,18403,-0.383,-2.19,0.018,0.052]
[193,"REACTOME_PLATELET_AGGREGATION_PLUG_FORMATION","Platelet Aggregation (Plug Formation)",21,7,1282,18403,0.533,1.6,0.019,0.056]
[194,"REACTOME_METAL_ION_SLC_TRANSPORTERS","Metal ion SLC transporters",19,11,4627,18403,0.542,1.59,0.02,0.058]
[195,"REACTOME_INWARDLY_RECTIFYING_K_CHANNELS","Inwardly rectifying K+ channels",25,13,18328,18403,-0.381,-1.79,0.02,0.058]
[196,"REACTOME_ADP_SIGNALLING_THROUGH_P2RY12","ADP signalling through P2Y purinoceptor 12",16,9,3024,18403,0.558,1.57,0.02,0.058]
[197,"REACTOME_P75NTR_SIGNALS_VIA_NFKB","p75NTR signals via NF-kB",12,11,6012,18403,0.595,1.56,0.02,0.058]
[198,"REACTOME_G2_M_CHECKPOINTS","G2/M Checkpoints",39,28,6402,18403,0.455,1.52,0.02,0.059]
[199,"REACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM","Chondroitin sulfate/dermatan sulfate metabolism",42,15,2588,18403,0.447,1.52,0.021,0.06]
[200,"REACTOME_NOD1_2_SIGNALING_PATHWAY","NOD1/2 Signaling Pathway",28,19,5480,18403,0.492,1.56,0.021,0.06]
[201,"REACTOME_CELL_JUNCTION_ORGANIZATION","Cell junction organization",54,21,3588,18403,0.422,1.48,0.021,0.06]
[202,"REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS","Apoptotic cleavage of cellular proteins",31,13,3986,18403,0.473,1.52,0.022,0.063]
[203,"REACTOME_TAK1_ACTIVATES_NFKB_BY_PHOSPHORYLATION_AND_ACTIVATION_OF_IKKS_COMPLEX","TAK1 activates NFkB by phosphorylation and activation of IKKs complex",22,21,7571,18403,0.517,1.57,0.023,0.066]
[204,"REACTOME_UNFOLDED_PROTEIN_RESPONSE","Unfolded Protein Response",70,35,5486,18403,0.4,1.44,0.024,0.067]
[205,"REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS","Signal regulatory protein (SIRP) family interactions",11,4,801,18403,0.609,1.55,0.025,0.069]
[206,"REACTOME_HS_GAG_DEGRADATION","HS-GAG degradation",17,8,2070,18403,0.541,1.54,0.026,0.072]
[207,"REACTOME_CLEAVAGE_OF_GROWING_TRANSCRIPT_IN_THE_TERMINATION_REGION_","Cleavage of Growing Transcript in the Termination Region ",42,27,6000,18403,0.44,1.49,0.026,0.072]
[208,"REACTOME_PROTEIN_FOLDING","Protein folding",45,20,3721,18403,0.436,1.49,0.026,0.072]
[209,"REACTOME_P75NTR_RECRUITS_SIGNALLING_COMPLEXES","p75NTR recruits signalling complexes",10,9,5480,18403,0.621,1.55,0.027,0.073]
[210,"REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES","Transport of inorganic cations/anions and amino acids/oligopeptides",65,18,18369,18403,-0.28,-1.64,0.027,0.074]
[211,"REACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX","Signaling by TGF-beta Receptor Complex",50,21,4048,18403,0.42,1.46,0.028,0.076]
[212,"REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS","Effects of PIP2 hydrolysis",19,8,18197,18403,-0.384,-1.67,0.028,0.077]
[213,"REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS","Amino acid and oligopeptide SLC transporters",35,11,18369,18403,-0.314,-1.63,0.029,0.079]
[214,"REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN","Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein",25,20,6711,18403,0.492,1.53,0.03,0.08]
[215,"REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1","IKK complex recruitment mediated by RIP1",10,6,2848,18403,0.616,1.54,0.03,0.081]
[216,"REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC","Prefoldin mediated transfer of substrate  to CCT/TriC",23,15,5703,18403,0.497,1.52,0.031,0.082]
[217,"REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI","RIP-mediated NFkB activation via DAI",18,17,7373,18403,0.526,1.52,0.031,0.083]
[218,"REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS","Antigen Activates B Cell Receptor Leading to Generation of Second Messengers",28,17,5615,18403,0.474,1.5,0.032,0.084]
[219,"REACTOME_TRAF6_MEDIATED_NFKB_ACTIVATION","TRAF6 mediated NF-kB activation",21,20,8010,18403,0.503,1.51,0.033,0.087]
[220,"REACTOME_DEADENYLATION_DEPENDENT_MRNA_DECAY","Deadenylation-dependent mRNA decay",37,26,7031,18403,0.441,1.47,0.033,0.087]
[221,"REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT","Chylomicron-mediated lipid transport",10,8,5205,18403,0.611,1.53,0.034,0.089]
[222,"REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING","Formation of ATP by chemiosmotic coupling",14,8,3140,18403,0.555,1.5,0.037,0.094]
[223,"REACTOME_MEIOSIS","Meiosis",73,23,18391,18403,-0.378,-2.34,0.037,0.095]
[224,"REACTOME_G_ALPHA1213_SIGNALLING_EVENTS","G alpha (12/13) signalling events",63,28,4789,18403,0.397,1.41,0.037,0.095]
[225,"REACTOME_THE_ROLE_OF_NEF_IN_HIV1_REPLICATION_AND_DISEASE_PATHOGENESIS","The role of Nef in HIV-1 replication and disease pathogenesis",27,17,6314,18403,0.476,1.5,0.039,0.099]
[226,"REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES","Ion transport by P-type ATPases",28,9,18316,18403,-0.329,-1.6,0.039,0.099]
[227,"REACTOME_G_ALPHA_S_SIGNALLING_EVENTS","G alpha (s) signalling events",74,31,18302,18403,-0.242,-1.47,0.04,0.1]
[228,"REACTOME_GABA_B_RECEPTOR_ACTIVATION","GABA B receptor activation",29,14,18243,18403,-0.317,-1.57,0.04,0.1]
[229,"REACTOME_POTASSIUM_CHANNELS","Potassium Channels",78,53,18355,18403,-0.53,-3.3,0.04,0.1]
[230,"REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP","Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)",10,6,3497,18403,0.596,1.49,0.04,0.1]
[231,"REACTOME_PYRIMIDINE_CATABOLISM","Pyrimidine catabolism",10,3,892,18403,0.596,1.49,0.04,0.1]
[232,"REACTOME_DAG_AND_IP3_SIGNALING","DAG and IP3 signaling",22,8,18274,18403,-0.344,-1.57,0.041,0.1]
[233,"REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN","Synthesis, Secretion, and Deacylation of Ghrelin",11,7,3702,18403,0.586,1.5,0.042,0.1]
[234,"REACTOME_NUCLEAR_SIGNALING_BY_ERBB4","Nuclear signaling by ERBB4",27,14,4401,18403,0.47,1.48,0.042,0.1]
[235,"REACTOME_TRANS_GOLGI_NETWORK_VESICLE_BUDDING","trans-Golgi Network Vesicle Budding",57,34,6396,18403,0.394,1.39,0.043,0.1]
[236,"REACTOME_KERATAN_SULFATE_BIOSYNTHESIS","Keratan sulfate biosynthesis",20,8,2937,18403,0.497,1.48,0.045,0.11]
[237,"REACTOME_RNA_POL_I_RNA_POL_III_AND_MITOCHONDRIAL_TRANSCRIPTION","RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription",82,23,18391,18403,-0.368,-2.32,0.045,0.11]
[238,"REACTOME_DNA_STRAND_ELONGATION","DNA strand elongation",30,23,7106,18403,0.454,1.46,0.046,0.11]
[239,"REACTOME_BOTULINUM_NEUROTOXICITY","Botulinum neurotoxicity",16,6,18344,18403,-0.381,-1.56,0.046,0.11]
[240,"REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES","Synthesis and interconversion of nucleotide di- and triphosphates",18,16,7271,18403,0.51,1.48,0.049,0.12]
[241,"REACTOME_MITOTIC_PROMETAPHASE","Mitotic Prometaphase",73,50,7725,18403,0.375,1.36,0.051,0.12]
[242,"REACTOME_PHASE_II_CONJUGATION","Phase II conjugation",37,24,6297,18403,0.427,1.42,0.051,0.12]
[243,"REACTOME_METABOLISM_OF_POLYAMINES","Metabolism of polyamines",13,7,3198,18403,0.547,1.46,0.052,0.12]
[244,"REACTOME_L1CAM_INTERACTIONS","L1CAM interactions",68,20,18362,18403,-0.229,-1.38,0.053,0.12]
[245,"REACTOME_GLUCOSE_METABOLISM","Glucose metabolism",52,37,8092,18403,0.395,1.38,0.053,0.12]
[246,"REACTOME_SIGNALING_BY_RHO_GTPASES","Signaling by Rho GTPases",96,38,4476,18403,0.358,1.33,0.053,0.12]
[247,"REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER","Repair synthesis for gap-filling by DNA polymerase in TC-NER",13,12,6813,18403,0.545,1.46,0.053,0.12]
[248,"REACTOME_NFKB_ACTIVATION_THROUGH_FADD_RIP1_PATHWAY_MEDIATED_BY_CASPASE_8_AND10","NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10",12,6,2364,18403,0.556,1.45,0.054,0.13]
[249,"REACTOME_GLYCOSPHINGOLIPID_METABOLISM","Glycosphingolipid metabolism",28,14,3185,18403,0.455,1.44,0.055,0.13]
[250,"REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION","SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion",13,6,3236,18403,0.543,1.45,0.055,0.13]
[251,"REACTOME_HDL_MEDIATED_LIPID_TRANSPORT","HDL-mediated lipid transport",10,5,2959,18403,0.585,1.46,0.055,0.13]
[252,"REACTOME_CHROMOSOME_MAINTENANCE","Chromosome Maintenance",90,16,18391,18403,-0.237,-1.55,0.056,0.13]
[253,"REACTOME_PHOSPHOLIPASE_C_MEDIATED_CASCADE","Phospholipase C-mediated cascade",34,12,18274,18403,-0.286,-1.46,0.057,0.13]
[254,"REACTOME_INTEGRATION_OF_ENERGY_METABOLISM","Integration of energy metabolism",91,20,18355,18403,-0.203,-1.34,0.059,0.13]
[255,"REACTOME_BASIGIN_INTERACTIONS","Basigin interactions",25,13,4435,18403,0.464,1.44,0.059,0.13]
[256,"REACTOME_MEMBRANE_TRAFFICKING","Membrane Trafficking",115,65,6798,18403,0.343,1.29,0.06,0.13]
[257,"REACTOME_CS_DS_DEGRADATION","CS/DS degradation",10,4,1804,18403,0.579,1.45,0.06,0.13]
[258,"REACTOME_ACETYLCHOLINE_BINDING_AND_DOWNSTREAM_EVENTS","Acetylcholine Binding And Downstream Events",10,5,18279,18403,-0.453,-1.53,0.061,0.14]
[259,"REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES","Metabolism of amino acids and derivatives",155,74,5952,18403,0.331,1.27,0.062,0.14]
[260,"REACTOME_APOPTOTIC_EXECUTION_PHASE","Apoptotic execution  phase",41,15,3533,18403,0.415,1.4,0.063,0.14]
[261,"REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS","SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs",11,10,6843,18403,0.564,1.44,0.064,0.14]
[262,"REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION","Transport to the Golgi and subsequent modification",31,21,5799,18403,0.435,1.4,0.064,0.14]
[263,"REACTOME_EXTENSION_OF_TELOMERES","Extension of Telomeres",25,19,7102,18403,0.458,1.42,0.068,0.15]
[264,"REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS","Thrombin signalling through proteinase activated receptors (PARs)",25,13,4746,18403,0.457,1.42,0.069,0.15]
[265,"REACTOME_RNA_POL_II_TRANSCRIPTION","RNA Polymerase II Transcription",95,61,7727,18403,0.35,1.29,0.07,0.15]
[266,"REACTOME_PEROXISOMAL_LIPID_METABOLISM","Peroxisomal lipid metabolism",19,13,6342,18403,0.483,1.42,0.07,0.15]
[267,"REACTOME_METABOLISM_OF_PORPHYRINS","Metabolism of porphyrins",10,6,3961,18403,0.571,1.43,0.071,0.15]
[268,"REACTOME_PYRIMIDINE_METABOLISM","Pyrimidine metabolism",22,6,1628,18403,0.467,1.42,0.073,0.16]
[269,"REACTOME_NRIF_SIGNALS_CELL_DEATH_FROM_THE_NUCLEUS","NRIF signals cell death from the nucleus",13,8,4048,18403,0.531,1.42,0.073,0.16]
[270,"REACTOME_PLC_BETA_MEDIATED_EVENTS","PLC beta mediated events",31,11,18274,18403,-0.266,-1.33,0.074,0.16]
[271,"REACTOME_EARLY_PHASE_OF_HIV_LIFE_CYCLE","Early Phase of HIV Life Cycle",14,10,5603,18403,0.519,1.41,0.074,0.16]
[272,"REACTOME_ADP_SIGNALLING_THROUGH_P2RY1","ADP signalling through P2Y purinoceptor 1",20,8,3024,18403,0.472,1.4,0.075,0.16]
[273,"REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLP1","Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)",12,7,3533,18403,0.536,1.4,0.076,0.16]
[274,"REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS","Glycerophospholipid biosynthesis",57,40,8437,18403,0.38,1.34,0.076,0.16]
[275,"REACTOME_DEVELOPMENTAL_BIOLOGY","Developmental Biology",300,89,3918,18403,0.3,1.18,0.078,0.16]
[276,"REACTOME_REGULATION_OF_KIT_SIGNALING","Regulation of KIT signaling",15,6,2536,18403,0.51,1.41,0.079,0.16]
[277,"REACTOME_G_PROTEIN_ACTIVATION","G-protein activation",21,8,3024,18403,0.465,1.4,0.08,0.17]
[278,"REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S","Activation of Chaperone Genes by XBP1(S)",41,24,6323,18403,0.404,1.36,0.08,0.17]
[279,"REACTOME_BIOLOGICAL_OXIDATIONS","Biological oxidations",77,36,6297,18403,0.357,1.3,0.082,0.17]
[280,"REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS","Activation of ATR in response to replication stress",34,25,7193,18403,0.419,1.38,0.082,0.17]
[281,"REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING","Insulin Synthesis and Processing",16,4,18347,18403,-0.336,-1.38,0.084,0.17]
[282,"REACTOME_APC_C_CDC20_MEDIATED_DEGRADATION_OF_CYCLIN_B","APC/C:Cdc20 mediated degradation of Cyclin B",18,15,7402,18403,0.48,1.39,0.086,0.17]
[283,"REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR","Thromboxane signalling through TP receptor",19,8,3024,18403,0.474,1.39,0.087,0.17]
[284,"REACTOME_METABOLISM_OF_NON_CODING_RNA","Metabolism of non-coding RNA",45,30,6846,18403,0.39,1.33,0.087,0.17]
[285,"REACTOME_TRANSCRIPTION_COUPLED_NER_TC_NER","Transcription-coupled NER (TC-NER)",40,29,7659,18403,0.401,1.35,0.087,0.17]
[286,"REACTOME_ACTIVATION_OF_CHAPERONES_BY_ATF6_ALPHA","Activation of Chaperones by ATF6-alpha",11,6,3632,18403,0.544,1.39,0.087,0.17]
[287,"REACTOME_PHOSPHOLIPID_METABOLISM","Phospholipid metabolism",142,87,7906,18403,0.326,1.24,0.088,0.17]
[288,"REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION","SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription",21,15,7016,18403,0.461,1.38,0.088,0.17]
[289,"REACTOME_SYNTHESIS_OF_PA","Synthesis of PA",17,8,4352,18403,0.485,1.39,0.088,0.18]
[290,"REACTOME_G_PROTEIN_BETA_GAMMA_SIGNALLING","G-protein beta:gamma signalling",24,10,3024,18403,0.448,1.38,0.088,0.18]
[291,"REACTOME_LYSOSOME_VESICLE_BIOGENESIS","Lysosome Vesicle Biogenesis",23,14,5640,18403,0.452,1.38,0.09,0.18]
[292,"REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS","G alpha (q) signalling events",126,23,1620,18403,0.331,1.25,0.092,0.18]
[293,"REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS","Amine compound SLC transporters",16,8,18206,18403,-0.33,-1.35,0.092,0.18]
[294,"REACTOME_INCRETIN_SYNTHESIS_SECRETION_AND_INACTIVATION","Incretin Synthesis, Secretion, and Inactivation",13,7,3533,18403,0.516,1.38,0.093,0.18]
[295,"REACTOME_CA_DEPENDENT_EVENTS","Ca-dependent events",19,7,18274,18403,-0.317,-1.38,0.095,0.18]
[296,"REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY","Post-chaperonin tubulin folding pathway",13,7,4274,18403,0.514,1.37,0.096,0.19]
[297,"REACTOME_APC_CDC20_MEDIATED_DEGRADATION_OF_NEK2A","APC-Cdc20 mediated degradation of Nek2A",20,17,7725,18403,0.464,1.38,0.096,0.19]
[298,"REACTOME_MTORC1_MEDIATED_SIGNALLING","mTORC1-mediated signalling",10,7,5975,18403,0.55,1.38,0.097,0.19]
[299,"REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA","G beta:gamma signalling through PI3Kgamma",21,9,3024,18403,0.455,1.37,0.1,0.19]
[300,"REACTOME_PERK_REGULATED_GENE_EXPRESSION","PERK regulated gene expression",24,13,5806,18403,0.441,1.36,0.1,0.19]
[301,"REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM","Transport of Mature Transcript to Cytoplasm",51,41,8859,18403,0.375,1.3,0.1,0.19]
[302,"REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION","Cyclin A/B1 associated events during G2/M transition",13,10,6402,18403,0.51,1.36,0.1,0.19]
[303,"REACTOME_NEF_MEDIATES_DOWN_MODULATION_OF_CELL_SURFACE_RECEPTORS_BY_RECRUITING_THEM_TO_CLATHRIN_ADAPTERS","Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters",21,12,6314,18403,0.453,1.36,0.1,0.2]
[304,"REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE","mRNA Decay by 5' to 3' Exoribonuclease",11,8,5963,18403,0.532,1.36,0.11,0.2]
[305,"REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION","PPARA Activates Gene Expression",84,27,3918,18403,0.342,1.25,0.11,0.2]
[306,"REACTOME_CD28_DEPENDENT_VAV1_PATHWAY","CD28 dependent Vav1 pathway",10,5,2685,18403,0.544,1.36,0.11,0.21]
[307,"REACTOME_CD28_CO_STIMULATION","CD28 co-stimulation",28,17,6150,18403,0.422,1.34,0.11,0.21]
[308,"REACTOME_G1_PHASE","G1 Phase",31,22,7215,18403,0.41,1.32,0.11,0.21]
[309,"REACTOME_HIV_LIFE_CYCLE","HIV Life Cycle",104,65,7727,18403,0.333,1.24,0.11,0.21]
[310,"REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS","Nucleotide-like (purinergic) receptors",10,5,2299,18403,0.54,1.35,0.12,0.21]
[311,"REACTOME_ABORTIVE_ELONGATION_OF_HIV1_TRANSCRIPT_IN_THE_ABSENCE_OF_TAT","Abortive elongation of HIV-1 transcript in the absence of Tat",21,17,7688,18403,0.446,1.34,0.12,0.21]
[312,"REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION","activated TAK1 mediates p38 MAPK activation",16,14,7571,18403,0.479,1.35,0.12,0.21]
[313,"REACTOME_MAP_KINASE_ACTIVATION_IN_TLR_CASCADE","MAP kinase activation in TLR cascade",43,27,7141,18403,0.381,1.29,0.12,0.22]
[314,"REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA","G beta:gamma signalling through PLC beta",16,7,3024,18403,0.477,1.34,0.12,0.22]
[315,"REACTOME_ENDOGENOUS_STEROLS","Endogenous sterols",10,4,2701,18403,0.539,1.35,0.12,0.22]
[316,"REACTOME_PROSTACYCLIN_SIGNALLING_THROUGH_PROSTACYCLIN_RECEPTOR","Prostacyclin signalling through prostacyclin receptor",15,9,4507,18403,0.485,1.34,0.12,0.22]
[317,"REACTOME_NEUROTRANSMITTER_RECEPTOR_BINDING_AND_DOWNSTREAM_TRANSMISSION_IN_THE_POSTSYNAPTIC_CELL","Neurotransmitter Receptor Binding And Downstream Transmission In The  Postsynaptic Cell",110,53,18402,18403,-0.48,-3.18,0.12,0.23]
[318,"REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS","Glycogen breakdown (glycogenolysis)",14,12,7590,18403,0.491,1.33,0.13,0.23]
[319,"REACTOME_TRANSPORT_OF_GLUCOSE_AND_OTHER_SUGARS_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS","Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds",61,16,2928,18403,0.357,1.27,0.13,0.23]
[320,"REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS","A tetrasaccharide linker sequence is required for GAG synthesis",23,7,1769,18403,0.433,1.32,0.13,0.23]
[321,"REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE","Nitric oxide stimulates guanylate cyclase",20,10,18292,18403,-0.301,-1.33,0.13,0.23]
[322,"REACTOME_NUCLEOTIDE_EXCISION_REPAIR","Nucleotide Excision Repair",45,31,7659,18403,0.373,1.27,0.13,0.24]
[323,"REACTOME_LAGGING_STRAND_SYNTHESIS","Lagging Strand Synthesis",19,14,7097,18403,0.451,1.33,0.13,0.24]
[324,"REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS","Post-translational modification: synthesis of GPI-anchored proteins",25,16,6606,18403,0.423,1.31,0.13,0.24]
[325,"REACTOME_DSCAM_INTERACTIONS","DSCAM interactions",10,7,17979,18403,-0.387,-1.31,0.13,0.24]
[326,"REACTOME_GASTRIN_CREB_SIGNALLING_PATHWAY_VIA_PKC_AND_MAPK","Gastrin-CREB signalling pathway via PKC and MAPK",142,25,1620,18403,0.312,1.19,0.14,0.24]
[327,"REACTOME_DNA_REPAIR","DNA Repair",90,56,7492,18403,0.332,1.22,0.14,0.25]
[328,"REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS","Synthesis of substrates in N-glycan biosythesis",14,11,6711,18403,0.482,1.31,0.14,0.25]
[329,"REACTOME_PHOSPHORYLATION_OF_THE_APC_C","Phosphorylation of the APC/C",16,13,7402,18403,0.464,1.31,0.14,0.25]
[330,"REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES","Transmission across Chemical Synapses",148,79,18402,18403,-0.559,-4.28,0.14,0.25]
[331,"REACTOME_MRNA_3_END_PROCESSING","mRNA 3'-end processing",33,19,5742,18403,0.393,1.29,0.14,0.25]
[332,"REACTOME_SIGNALING_BY_SCF_KIT","Signaling by SCF-KIT",64,32,6206,18403,0.35,1.25,0.14,0.25]
[333,"REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS","Phase 1 - Functionalization of compounds",40,6,1204,18403,0.377,1.27,0.15,0.25]
[334,"REACTOME_DEADENYLATION_OF_MRNA","Deadenylation of mRNA",17,13,6924,18403,0.455,1.3,0.15,0.25]
[335,"REACTOME_ZINC_TRANSPORTERS","Zinc transporters",12,7,3982,18403,0.499,1.31,0.15,0.25]
[336,"REACTOME_TIE2_SIGNALING","Tie2 Signaling",13,5,2658,18403,0.489,1.31,0.15,0.25]
[337,"REACTOME_SIGNALING_BY_ROBO_RECEPTOR","Signaling by Robo receptor",21,8,2685,18403,0.433,1.3,0.15,0.25]
[338,"REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC","Formation of tubulin folding intermediates by CCT/TriC",17,6,2203,18403,0.453,1.3,0.15,0.25]
[339,"REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION","Cytosolic tRNA aminoacylation",22,19,8572,18403,0.43,1.3,0.15,0.25]
[340,"REACTOME_G1_S_SPECIFIC_TRANSCRIPTION","G1/S-Specific Transcription",16,11,6692,18403,0.46,1.3,0.15,0.25]
[341,"REACTOME_INFLAMMASOMES","Inflammasomes",14,6,3582,18403,0.478,1.3,0.15,0.25]
[342,"REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE","Inhibition of Insulin Secretion by Adrenaline/Noradrenaline",18,7,3024,18403,0.449,1.3,0.15,0.26]
[343,"REACTOME_PURINE_SALVAGE","Purine salvage",12,9,7149,18403,0.495,1.3,0.16,0.26]
[344,"REACTOME_INHIBITION_OF_THE_PROTEOLYTIC_ACTIVITY_OF_APC_C_REQUIRED_FOR_THE_ONSET_OF_ANAPHASE_BY_MITOTIC_SPINDLE_CHECKPOINT_COMPONENTS","Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components",17,14,7725,18403,0.451,1.29,0.16,0.26]
[345,"REACTOME_SPHINGOLIPID_METABOLISM","Sphingolipid metabolism",51,36,7900,18403,0.356,1.24,0.16,0.27]
[346,"REACTOME_TRANSFERRIN_ENDOCYTOSIS_AND_RECYCLING","Transferrin endocytosis and recycling",23,8,3712,18403,0.418,1.28,0.16,0.27]
[347,"REACTOME_NEPHRIN_INTERACTIONS","Nephrin interactions",17,6,3709,18403,0.448,1.28,0.17,0.28]
[348,"REACTOME_G0_AND_EARLY_G1","G0 and Early G1",21,7,2675,18403,0.425,1.28,0.17,0.28]
[349,"REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS","Golgi Associated Vesicle Biogenesis",50,28,6396,18403,0.356,1.23,0.17,0.28]
[350,"REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING","p75 NTR receptor-mediated signalling",73,40,6613,18403,0.334,1.21,0.17,0.28]
[351,"REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND","Removal of the Flap Intermediate from the C-strand",10,7,5925,18403,0.508,1.27,0.18,0.3]
[352,"REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR","Regulated proteolysis of p75NTR",10,10,8155,18403,0.507,1.27,0.19,0.3]
[353,"REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION","Sema3A PAK dependent Axon repulsion",13,11,7842,18403,0.468,1.25,0.19,0.31]
[354,"REACTOME_TRNA_AMINOACYLATION","tRNA Aminoacylation",38,28,8572,18403,0.365,1.22,0.2,0.32]
[355,"REACTOME_E2F_MEDIATED_REGULATION_OF_DNA_REPLICATION","E2F mediated regulation of DNA replication",31,20,7193,18403,0.382,1.23,0.2,0.32]
[356,"REACTOME_P38MAPK_EVENTS","p38MAPK events",13,7,4277,18403,0.465,1.24,0.2,0.32]
[357,"REACTOME_RNA_POL_II_PRE_TRANSCRIPTION_EVENTS","RNA Polymerase II Pre-transcription Events",54,34,7727,18403,0.342,1.2,0.2,0.32]
[358,"REACTOME_SIGNALING_BY_ERBB4","Signaling by ERBB4",68,35,6206,18403,0.331,1.19,0.21,0.33]
[359,"REACTOME_POL_SWITCHING","Polymerase switching",13,10,7097,18403,0.462,1.23,0.21,0.33]
[360,"REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES","Cytosolic sulfonation of small molecules",11,12,18319,18403,-0.336,-1.21,0.21,0.33]
[361,"REACTOME_TRANSCRIPTIONAL_ACTIVITY_OF_SMAD2_SMAD3_SMAD4_HETEROTRIMER","Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer",32,24,8744,18403,0.375,1.22,0.21,0.33]
[362,"REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION","PTM: gamma carboxylation, hypusine formation and arylsulfatase activation",18,12,6909,18403,0.426,1.23,0.21,0.33]
[363,"REACTOME_PURINE_METABOLISM","Purine metabolism",29,21,7529,18403,0.382,1.22,0.21,0.34]
[364,"REACTOME_GLUCONEOGENESIS","Gluconeogenesis",22,12,6009,18403,0.405,1.23,0.21,0.34]
[365,"REACTOME_SIGNALING_BY_HIPPO","Signaling by Hippo",19,9,5629,18403,0.415,1.22,0.22,0.34]
[366,"REACTOME_ACTIVATION_OF_GENES_BY_ATF4","Activation of Genes by ATF4",21,13,7493,18403,0.405,1.22,0.22,0.35]
[367,"REACTOME_INSULIN_RECEPTOR_RECYCLING","Insulin receptor recycling",21,7,3712,18403,0.402,1.21,0.23,0.36]
[368,"REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS","Intrinsic Pathway for Apoptosis",27,16,6537,18403,0.385,1.21,0.23,0.36]
[369,"REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS","Chondroitin sulfate biosynthesis",18,6,2588,18403,0.418,1.21,0.23,0.36]
[370,"REACTOME_CGMP_EFFECTS","cGMP effects",15,8,18292,18403,-0.285,-1.16,0.24,0.37]
[371,"REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS","O-linked glycosylation of mucins",37,16,4178,18403,0.355,1.18,0.24,0.37]
[372,"REACTOME_ENOS_ACTIVATION_AND_REGULATION","eNOS activation and regulation",18,10,5190,18403,0.414,1.2,0.24,0.37]
[373,"REACTOME_MITOTIC_G2_G2_M_PHASES","Mitotic G2-G2/M phases",62,32,6475,18403,0.328,1.17,0.24,0.37]
[374,"REACTOME_PROCESSING_OF_CAPPED_INTRONLESS_PRE_MRNA","Processing of Capped Intronless Pre-mRNA",22,13,6000,18403,0.396,1.2,0.24,0.37]
[375,"REACTOME_CHOLESTEROL_BIOSYNTHESIS","Cholesterol biosynthesis",13,14,17230,18403,-0.307,-1.16,0.24,0.37]
[376,"REACTOME_PYRUVATE_METABOLISM","Pyruvate metabolism",15,5,3135,18403,0.434,1.2,0.24,0.37]
[377,"REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS","Adherens junctions interactions",19,8,18229,18403,-0.267,-1.16,0.25,0.38]
[378,"REACTOME_TRANSCRIPTION","Transcription",162,20,18391,18403,-0.169,-1.28,0.25,0.38]
[379,"REACTOME_ELONGATION_ARREST_AND_RECOVERY","Elongation arrest and recovery",26,18,7688,18403,0.379,1.18,0.25,0.38]
[380,"REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS","Activated NOTCH1 Transmits Signal to the Nucleus",21,10,4519,18403,0.396,1.19,0.25,0.38]
[381,"REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS","Viral Messenger RNA Synthesis",13,10,7492,18403,0.446,1.19,0.25,0.38]
[382,"REACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE","Cell death signalling via NRAGE, NRIF and NADE",52,19,4294,18403,0.331,1.15,0.26,0.38]
[383,"REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING","RNA Polymerase II Transcription Pre-Initiation And Promoter Opening",39,14,3694,18403,0.347,1.17,0.26,0.38]
[384,"REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR","Signaling by constitutively active EGFR",15,15,9560,18403,0.428,1.18,0.26,0.38]
[385,"REACTOME_GLOBAL_GENOMIC_NER_GG_NER","Global Genomic NER (GG-NER)",31,24,8655,18403,0.365,1.18,0.26,0.38]
[386,"REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE","Late Phase of HIV Life Cycle",90,59,8464,18403,0.307,1.13,0.26,0.38]
[387,"REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE","Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase",15,11,7402,18403,0.427,1.18,0.26,0.38]
[388,"REACTOME_PKB_MEDIATED_EVENTS","PKB-mediated events",22,14,7406,18403,0.39,1.18,0.26,0.39]
[389,"REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS","Association of TriC/CCT with target proteins during biosynthesis",25,10,3721,18403,0.38,1.18,0.27,0.39]
[390,"REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX","Activation of the pre-replicative complex",28,18,7193,18403,0.37,1.17,0.27,0.39]
[391,"REACTOME_N_GLYCAN_TRIMMING_IN_THE_ER_AND_CALNEXIN_CALRETICULIN_CYCLE","N-glycan trimming in the ER and Calnexin/Calreticulin cycle",13,7,4720,18403,0.439,1.17,0.27,0.4]
[392,"REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION","Transcriptional Regulation of White Adipocyte Differentiation",57,44,9522,18403,0.324,1.14,0.27,0.4]
[393,"REACTOME_REGULATION_OF_HYPOXIA_INDUCIBLE_FACTOR_HIF_BY_OXYGEN","Regulation of Hypoxia-inducible Factor (HIF) by Oxygen",17,8,4401,18403,0.411,1.17,0.27,0.4]
[394,"REACTOME_UNWINDING_OF_DNA","Unwinding of DNA",11,9,7106,18403,0.46,1.17,0.27,0.4]
[395,"REACTOME_DOUBLE_STRAND_BREAK_REPAIR","Double-Strand Break Repair",19,16,8653,18403,0.398,1.17,0.27,0.4]
[396,"REACTOME_FORMATION_OF_THE_HIV1_EARLY_ELONGATION_COMPLEX","Formation of the HIV-1 Early Elongation Complex",31,21,7688,18403,0.359,1.16,0.27,0.4]
[397,"REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS","Homologous recombination repair of replication-independent double-strand breaks",13,10,7397,18403,0.435,1.16,0.28,0.41]
[398,"REACTOME_PROCESSIVE_SYNTHESIS_ON_THE_LAGGING_STRAND","Processive synthesis on the lagging strand",15,10,7097,18403,0.42,1.16,0.28,0.41]
[399,"REACTOME_MAPK_TARGETS_NUCLEAR_EVENTS_MEDIATED_BY_MAP_KINASES","MAPK targets/ Nuclear events mediated by MAP kinases",25,15,7141,18403,0.374,1.16,0.29,0.41]
[400,"REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY","NEP/NS2 Interacts with the Cellular Export Machinery",25,21,9150,18403,0.374,1.16,0.29,0.41]
[401,"REACTOME_CALNEXIN_CALRETICULIN_CYCLE","Calnexin/calreticulin cycle",11,6,4720,18403,0.451,1.15,0.29,0.42]
[402,"REACTOME_HS_GAG_BIOSYNTHESIS","HS-GAG biosynthesis",26,11,4169,18403,0.369,1.15,0.29,0.42]
[403,"REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS","Transport of Ribonucleoproteins into the Host Nucleus",25,21,9150,18403,0.373,1.16,0.29,0.42]
[404,"REACTOME_TRANSPORT_OF_MATURE_MRNA_DERIVED_FROM_AN_INTRONLESS_TRANSCRIPT","Transport of Mature mRNA Derived from an Intronless Transcript",31,25,9150,18403,0.352,1.14,0.3,0.42]
[405,"REACTOME_ACTIVATION_OF_KAINATE_RECEPTORS_UPON_GLUTAMATE_BINDING","Activation of Kainate Receptors upon glutamate binding",23,5,1203,18403,0.377,1.15,0.3,0.42]
[406,"REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB","PKA-mediated phosphorylation of CREB",11,4,18043,18403,-0.312,-1.12,0.3,0.43]
[407,"REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION","Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation",12,8,6120,18403,0.437,1.14,0.31,0.43]
[408,"REACTOME_AQUAPORIN_MEDIATED_TRANSPORT","Aquaporin-mediated transport",32,14,4730,18403,0.347,1.13,0.31,0.43]
[409,"REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION","BMAL1:CLOCK/NPAS2 Activates Circadian Expression",27,4,1267,18403,0.359,1.13,0.31,0.43]
[410,"REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS","G alpha (z) signalling events",33,7,1203,18403,0.345,1.13,0.31,0.43]
[411,"REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_GLUCAGON_LIKE_PEPTIDE1","Regulation of Insulin Secretion by Glucagon-like Peptide-1",32,7,1203,18403,0.346,1.12,0.32,0.44]
[412,"REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES","Loss of Nlp from mitotic centrosomes",45,32,8891,18403,0.326,1.11,0.32,0.45]
[413,"REACTOME_HEPARAN_SULFATE_HEPARIN_HS_GAG_METABOLISM","Heparan sulfate/heparin (HS-GAG) metabolism",46,23,6045,18403,0.323,1.11,0.33,0.45]
[414,"REACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION","Nuclear Events (kinase and transcription factor activation)",21,13,7141,18403,0.374,1.12,0.33,0.46]
[415,"REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1","JNK (c-Jun kinases) phosphorylation and  activation mediated by activated human TAK1",13,8,5480,18403,0.421,1.12,0.33,0.46]
[416,"REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS","Interactions of Vpr with host cellular proteins",30,24,9150,18403,0.345,1.11,0.33,0.46]
[417,"REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP","Destabilization of mRNA by Tristetraprolin (TTP)",14,8,7031,18403,0.413,1.12,0.33,0.46]
[418,"REACTOME_SULFUR_AMINO_ACID_METABOLISM","Sulfur amino acid metabolism",18,10,5781,18403,0.387,1.12,0.33,0.46]
[419,"REACTOME_REGULATION_OF_WATER_BALANCE_BY_RENAL_AQUAPORINS","Regulation of Water Balance by Renal Aquaporins",28,12,4507,18403,0.35,1.11,0.34,0.46]
[420,"REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION","Factors involved in megakaryocyte development and platelet production",85,33,4517,18403,0.295,1.08,0.35,0.47]
[421,"REACTOME_FORMATION_OF_RNA_POL_II_ELONGATION_COMPLEX_","Formation of RNA Pol II elongation complex ",38,24,7688,18403,0.329,1.1,0.35,0.48]
[422,"REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS","Purine ribonucleoside monophosphate biosynthesis",10,8,7529,18403,0.437,1.09,0.36,0.49]
[423,"REACTOME_GLUCOSE_TRANSPORT","Glucose transport",34,27,9686,18403,0.331,1.09,0.37,0.5]
[424,"REACTOME_N_GLYCAN_ANTENNAE_ELONGATION","N-Glycan antennae elongation",13,6,2937,18403,0.41,1.09,0.37,0.5]
[425,"REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER","RNA Polymerase III Transcription Initiation From Type 3 Promoter",22,18,9841,18403,0.359,1.09,0.37,0.5]
[426,"REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES","Transport of vitamins, nucleosides, and related molecules",23,14,7108,18403,0.357,1.09,0.37,0.5]
[427,"REACTOME_SIGNALLING_TO_ERKS","Signalling to ERKs",32,9,2327,18403,0.334,1.09,0.37,0.5]
[428,"REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING","Spry regulation of FGF signaling",11,7,6687,18403,0.425,1.09,0.37,0.5]
[429,"REACTOME_FATTY_ACID_TRIACYLGLYCEROL_AND_KETONE_BODY_METABOLISM","Fatty acid, triacylglycerol, and ketone body metabolism",134,61,6840,18403,0.278,1.06,0.37,0.5]
[430,"REACTOME_ERK_MAPK_TARGETS","ERK/MAPK targets",18,11,7141,18403,0.376,1.09,0.37,0.5]
[431,"REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING","DCC mediated attractive signaling",11,4,2685,18403,0.423,1.08,0.38,0.5]
[432,"REACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES","Recruitment of mitotic centrosome proteins and complexes",49,21,5297,18403,0.31,1.07,0.38,0.5]
[433,"REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI","Synthesis of glycosylphosphatidylinositol (GPI)",16,14,9419,18403,0.383,1.08,0.38,0.5]
[434,"REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN","Regulation of Glucokinase by Glucokinase Regulatory Protein",25,22,10014,18403,0.348,1.08,0.38,0.5]
[435,"REACTOME_ERKS_ARE_INACTIVATED","ERKs are inactivated",10,7,7141,18403,0.431,1.08,0.38,0.5]
[436,"REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION","Amino acid synthesis and interconversion (transamination)",10,11,17928,18403,-0.306,-1.04,0.38,0.51]
[437,"REACTOME_MICRORNA_MIRNA_BIOGENESIS","MicroRNA (miRNA) Biogenesis",20,7,3524,18403,0.358,1.06,0.41,0.54]
[438,"REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM","Branched-chain amino acid catabolism",16,13,9182,18403,0.373,1.05,0.42,0.54]
[439,"REACTOME_FANCONI_ANEMIA_PATHWAY","Fanconi Anemia pathway",16,9,6449,18403,0.373,1.05,0.42,0.54]
[440,"REACTOME_DESTABILIZATION_OF_MRNA_BY_BRF1","Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)",14,8,7031,18403,0.389,1.06,0.42,0.55]
[441,"REACTOME_EGFR_DOWNREGULATION","EGFR downregulation",23,12,5764,18403,0.342,1.05,0.43,0.56]
[442,"REACTOME_SIGNAL_TRANSDUCTION_BY_L1","Signal transduction by L1",28,14,5764,18403,0.326,1.03,0.43,0.56]
[443,"REACTOME_PLATELET_SENSITIZATION_BY_LDL","Platelet sensitization by LDL",14,3,1672,18403,0.386,1.05,0.43,0.56]
[444,"REACTOME_MYOGENESIS","Myogenesis",18,7,3888,18403,0.36,1.04,0.43,0.56]
[445,"REACTOME_STRIATED_MUSCLE_CONTRACTION","Striated Muscle Contraction",17,6,2782,18403,0.365,1.04,0.43,0.56]
[446,"REACTOME_CIRCADIAN_CLOCK","Circadian Clock",39,16,5989,18403,0.31,1.04,0.43,0.56]
[447,"REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT","Mitochondrial Protein Import",47,35,9432,18403,0.303,1.04,0.43,0.56]
[448,"REACTOME_SIGNALLING_TO_RAS","Signalling to RAS",23,13,6516,18403,0.339,1.04,0.44,0.57]
[449,"REACTOME_RORA_ACTIVATES_CIRCADIAN_EXPRESSION","RORA Activates Circadian Expression",19,19,15916,18403,-0.231,-1,0.45,0.57]
[450,"REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY","Downregulation of SMAD2/3:SMAD4 transcriptional activity",18,16,10084,18403,0.356,1.03,0.45,0.57]
[451,"REACTOME_FORMATION_OF_TRANSCRIPTION_COUPLED_NER_TC_NER_REPAIR_COMPLEX","Formation of transcription-coupled NER (TC-NER) repair complex",26,16,7659,18403,0.327,1.02,0.45,0.57]
[452,"REACTOME_BASE_EXCISION_REPAIR","Base Excision Repair",16,10,7086,18403,0.361,1.02,0.45,0.58]
[453,"REACTOME_SHC1_EVENTS_IN_EGFR_SIGNALING","SHC1 events in EGFR signaling",12,12,10164,18403,0.393,1.03,0.46,0.58]
[454,"REACTOME_GLYCOLYSIS","Glycolysis",26,16,8092,18403,0.325,1.01,0.46,0.58]
[455,"REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING","CD28 dependent PI3K/Akt signaling",19,10,6150,18403,0.345,1.02,0.46,0.58]
[456,"REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI","Pre-NOTCH Processing in Golgi",14,12,9341,18403,0.379,1.03,0.46,0.58]
[457,"REACTOME_RNA_POL_III_TRANSCRIPTION","RNA Polymerase III Transcription",27,21,10149,18403,0.32,1.01,0.47,0.59]
[458,"REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA","Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha",13,9,7045,18403,0.379,1.01,0.47,0.59]
[459,"REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION","Mitochondrial tRNA aminoacylation",19,11,7059,18403,0.343,1.01,0.47,0.59]
[460,"REACTOME_SOS_MEDIATED_SIGNALLING","SOS-mediated signalling",11,11,10164,18403,0.393,1,0.48,0.6]
[461,"REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS","Proteolytic cleavage of SNARE complex proteins",14,4,18315,18403,-0.255,-1,0.48,0.6]
[462,"REACTOME_SIGNALING_BY_NOTCH3","Signaling by NOTCH3",10,9,8975,18403,0.399,1,0.49,0.6]
[463,"REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT","Endosomal Sorting Complex Required For Transport (ESCRT)",25,16,8114,18403,0.322,1,0.49,0.6]
[464,"REACTOME_SIGNALING_BY_NOTCH2","Signaling by NOTCH2",10,9,8975,18403,0.396,0.992,0.49,0.61]
[465,"REACTOME_SIGNALING_BY_NOTCH4","Signaling by NOTCH4",10,9,8975,18403,0.396,0.991,0.49,0.61]
[466,"REACTOME_PYRUVATE_METABOLISM_AND_CITRIC_ACID_TCA_CYCLE","Pyruvate metabolism and Citric Acid (TCA) cycle",33,24,9681,18403,0.304,0.994,0.5,0.61]
[467,"REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS","Inhibition  of voltage gated Ca2+ channels via Gbeta/gamma subunits",20,5,1642,18403,0.332,0.986,0.5,0.61]
[468,"REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS","Metabolism of vitamins and cofactors",43,10,3094,18403,0.29,0.985,0.51,0.63]
[469,"REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER","Formation of incision complex in GG-NER",20,18,10580,18403,0.329,0.977,0.52,0.63]
[470,"REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION","Mitochondrial Fatty Acid Beta-Oxidation",13,12,10271,18403,0.365,0.973,0.52,0.63]
[471,"REACTOME_MRNA_CAPPING","mRNA Capping",27,16,7659,18403,0.309,0.971,0.52,0.64]
[472,"REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE","Activated AMPK stimulates fatty-acid oxidation in muscle",14,8,6995,18403,0.361,0.979,0.52,0.64]
[473,"REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS","Sphingolipid de novo biosynthesis",23,15,8312,18403,0.317,0.97,0.53,0.64]
[474,"REACTOME_SIGNALING_BY_NOTCH","Signaling by NOTCH",83,30,4687,18403,0.269,0.984,0.53,0.64]
[475,"REACTOME_RNA_POL_III_CHAIN_ELONGATION","RNA Polymerase III Chain Elongation",15,12,9841,18403,0.349,0.962,0.53,0.64]
[476,"REACTOME_PROLONGED_ERK_ACTIVATION_EVENTS","Prolonged ERK activation events",16,14,10164,18403,0.34,0.958,0.54,0.64]
[477,"REACTOME_RESOLUTION_OF_AP_SITES_VIA_THE_MULTIPLE_NUCLEOTIDE_PATCH_REPLACEMENT_PATHWAY","Resolution of AP sites via the multiple-nucleotide patch replacement pathway",15,12,9303,18403,0.347,0.958,0.54,0.64]
[478,"REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE","Cytochrome P450 - arranged by substrate type",30,4,1204,18403,0.3,0.964,0.54,0.64]
[479,"REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE","Synthesis of PIPs at the plasma membrane",22,5,2613,18403,0.318,0.965,0.54,0.64]
[480,"REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK","NRAGE signals death through JNK",38,10,3282,18403,0.29,0.97,0.54,0.65]
[481,"REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX","CDC6 association with the ORC:origin complex",11,10,9711,18403,0.376,0.96,0.54,0.65]
[482,"REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS","Class B/2 (Secretin family receptors)",59,13,2517,18403,0.274,0.967,0.54,0.65]
[483,"REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_2_PROMOTER","RNA Polymerase III Transcription Initiation From Type 2 Promoter",19,15,10149,18403,0.326,0.959,0.54,0.65]
[484,"REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS","Signaling by FGFR1 fusion mutants",16,15,10189,18403,0.338,0.952,0.55,0.65]
[485,"REACTOME_SIGNALING_BY_BMP","Signaling by BMP",16,6,18082,18403,-0.224,-0.918,0.56,0.66]
[486,"REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION","RNA Polymerase III Transcription Termination",17,13,9841,18403,0.327,0.935,0.57,0.67]
[487,"REACTOME_REGULATORY_RNA_PATHWAYS","Regulatory RNA pathways",23,7,3524,18403,0.307,0.938,0.57,0.67]
[488,"REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI","N-glycan antennae elongation in the medial/trans-Golgi",17,10,5799,18403,0.327,0.934,0.57,0.67]
[489,"REACTOME_SIGNALING_BY_NOTCH1","Signaling by NOTCH1",55,20,4519,18403,0.272,0.955,0.57,0.67]
[490,"REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX","Association of licensing factors with the pre-replicative complex",13,11,9711,18403,0.347,0.928,0.57,0.67]
[491,"REACTOME_SIGNALLING_BY_NGF","Signalling by NGF",183,88,6687,18403,0.251,0.971,0.58,0.68]
[492,"REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1","Inhibition of replication initiation of damaged DNA by RB1/E2F1",11,7,7097,18403,0.363,0.926,0.59,0.68]
[493,"REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA","Circadian Repression of Expression by REV-ERBA",17,17,15916,18403,-0.214,-0.892,0.59,0.68]
[494,"REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS","Glucagon-type ligand receptors",23,4,1203,18403,0.303,0.925,0.59,0.68]
[495,"REACTOME_PI3K_CASCADE","PI3K Cascade",47,23,6995,18403,0.273,0.939,0.59,0.68]
[496,"REACTOME_METABOLISM_OF_STEROID_HORMONES_AND_VITAMINS_A_AND_D","Metabolism of steroid hormones and vitamins A and D",22,6,3296,18403,0.303,0.918,0.59,0.69]
[497,"REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING","SHC1 events in ERBB4 signaling",16,4,2310,18403,0.325,0.915,0.59,0.69]
[498,"REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP","Destabilization of mRNA by KSRP",15,9,7493,18403,0.332,0.915,0.6,0.69]
[499,"REACTOME_ARMS_MEDIATED_ACTIVATION","ARMS-mediated activation",14,12,10164,18403,0.334,0.905,0.6,0.69]
[500,"REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE","Beta-catenin phosphorylation cascade",15,16,16456,18403,-0.221,-0.897,0.61,0.69]
[501,"REACTOME_NEGATIVE_REGULATION_OF_FGFR_SIGNALING","Negative regulation of FGFR signaling",24,12,6889,18403,0.293,0.903,0.61,0.7]
[502,"REACTOME_RAP1_SIGNALLING","Rap1 signalling",12,3,1160,18403,0.342,0.895,0.62,0.71]
[503,"REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL","AKT phosphorylates targets in the cytosol",11,7,6465,18403,0.351,0.897,0.62,0.71]
[504,"REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS","Processing of Intronless Pre-mRNAs",13,11,9684,18403,0.332,0.888,0.62,0.71]
[505,"REACTOME_RECYCLING_PATHWAY_OF_L1","Recycling pathway of L1",23,11,5764,18403,0.29,0.886,0.63,0.72]
[506,"REACTOME_CTLA4_INHIBITORY_SIGNALING","CTLA4 inhibitory signaling",21,11,7188,18403,0.293,0.878,0.64,0.72]
[507,"REACTOME_GLUCAGON_SIGNALING_IN_METABOLIC_REGULATION","Glucagon signaling in metabolic regulation",22,8,4507,18403,0.289,0.875,0.64,0.73]
[508,"REACTOME_REGULATION_OF_INSULIN_SECRETION","Regulation of Insulin Secretion",68,20,3533,18403,0.254,0.914,0.65,0.73]
[509,"REACTOME_ACTIVATED_POINT_MUTANTS_OF_FGFR2","Activated point mutants of FGFR2",10,5,17586,18403,-0.251,-0.85,0.65,0.73]
[510,"REACTOME_SIGNALING_BY_INSULIN_RECEPTOR","Signaling by Insulin receptor",80,36,6995,18403,0.25,0.911,0.66,0.74]
[511,"REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION","E2F-enabled inhibition of pre-replication complex formation",10,8,9704,18403,0.34,0.852,0.67,0.76]
[512,"REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE","Citric acid cycle (TCA cycle)",17,15,10997,18403,0.297,0.847,0.69,0.77]
[513,"REACTOME_GAP_JUNCTION_TRAFFICKING","Gap junction trafficking",19,10,6412,18403,0.285,0.837,0.69,0.78]
[514,"REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS","Synthesis of very long-chain fatty acyl-CoAs",13,4,2970,18403,0.308,0.823,0.71,0.78]
[515,"REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE","Synthesis of PIPs at the Golgi membrane",12,9,9460,18403,0.316,0.826,0.71,0.78]
[516,"REACTOME_STEROID_HORMONES","Steroid hormones",20,5,3296,18403,0.278,0.825,0.71,0.78]
[517,"REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING","Pre-NOTCH Expression and Processing",35,17,7425,18403,0.257,0.849,0.71,0.78]
[518,"REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS","Eicosanoid ligand-binding receptors",12,3,18314,18403,-0.222,-0.819,0.71,0.78]
[519,"REACTOME_ENERGY_DEPENDENT_REGULATION_OF_MTOR_BY_LKB1_AMPK","Energy dependent regulation of mTOR by LKB1-AMPK",13,8,8579,18403,0.305,0.815,0.72,0.79]
[520,"REACTOME_SYNTHESIS_OF_PC","Synthesis of PC",13,8,8437,18403,0.302,0.805,0.73,0.8]
[521,"REACTOME_INSULIN_RECEPTOR_SIGNALLING_CASCADE","Insulin receptor signalling cascade",60,28,6995,18403,0.242,0.859,0.73,0.8]
[522,"REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION","RNA Polymerase I Transcription Termination",19,15,10580,18403,0.273,0.801,0.73,0.81]
[523,"REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE","Amino acid transport across the plasma membrane",23,2,421,18403,0.265,0.809,0.74,0.81]
[524,"REACTOME_SHC_MEDIATED_SIGNALLING","SHC-mediated signalling",12,11,10164,18403,0.305,0.797,0.74,0.81]
[525,"REACTOME_KINESINS","Kinesins",17,7,4517,18403,0.276,0.789,0.75,0.82]
[526,"REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN","Signalling to p38 via RIT and RIN",12,3,2310,18403,0.299,0.783,0.76,0.83]
[527,"REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS","Activation of BH3-only proteins",15,7,6320,18403,0.285,0.787,0.76,0.83]
[528,"REACTOME_SIGNALING_BY_FGFR_MUTANTS","Signaling by FGFR mutants",33,26,10189,18403,0.245,0.8,0.76,0.83]
[529,"REACTOME_OPIOID_SIGNALLING","Opioid Signalling",56,11,2537,18403,0.236,0.831,0.76,0.83]
[530,"REACTOME_GRB2_EVENTS_IN_ERBB2_SIGNALING","GRB2 events in ERBB2 signaling",17,8,6619,18403,0.272,0.777,0.76,0.83]
[531,"REACTOME_NETRIN1_SIGNALING","Netrin-1 signaling",33,7,18298,18403,-0.168,-0.838,0.77,0.83]
[532,"REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT","SLC-mediated transmembrane transport",177,41,3460,18403,0.228,0.879,0.77,0.83]
[533,"REACTOME_TRIGLYCERIDE_BIOSYNTHESIS","Triglyceride Biosynthesis",29,17,8607,18403,0.244,0.777,0.78,0.84]
[534,"REACTOME_RNA_POL_I_TRANSCRIPTION_INITIATION","RNA Polymerase I Transcription Initiation",22,20,12236,18403,0.251,0.762,0.78,0.84]
[535,"REACTOME_SHC_RELATED_EVENTS","SHC-related events",13,11,10164,18403,0.285,0.76,0.79,0.84]
[536,"REACTOME_PI3K_AKT_ACTIVATION","PI3K/AKT activation",29,19,9171,18403,0.242,0.773,0.79,0.84]
[537,"REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS","Fatty Acyl-CoA Biosynthesis",17,4,2970,18403,0.261,0.746,0.8,0.85]
[538,"REACTOME_SIGNALING_BY_FGFR1_MUTANTS","Signaling by FGFR1 mutants",24,19,10189,18403,0.244,0.752,0.8,0.86]
[539,"REACTOME_SHC_MEDIATED_CASCADE","SHC-mediated cascade",18,7,5615,18403,0.255,0.739,0.81,0.86]
[540,"REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION","NOTCH1 Intracellular Domain Regulates Transcription",36,12,4511,18403,0.231,0.765,0.81,0.86]
[541,"REACTOME_FGFR_LIGAND_BINDING_AND_ACTIVATION","FGFR ligand binding and activation",12,5,17586,18403,-0.207,-0.762,0.81,0.86]
[542,"REACTOME_PI_METABOLISM","PI Metabolism",34,21,9637,18403,0.224,0.736,0.83,0.88]
[543,"REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING","Retrograde neurotrophin signalling",12,13,18016,18403,-0.2,-0.736,0.83,0.88]
[544,"REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1","Regulation of AMPK activity via LKB1",12,7,8579,18403,0.272,0.71,0.84,0.89]
[545,"REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM","Vitamin B5 (pantothenate) metabolism",10,1,516,18403,0.28,0.702,0.85,0.89]
[546,"REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY","Notch-HLH transcription pathway",10,10,12415,18403,0.276,0.691,0.86,0.9]
[547,"REACTOME_TIGHT_JUNCTION_INTERACTIONS","Tight junction interactions",16,2,1551,18403,0.249,0.702,0.86,0.9]
[548,"REACTOME_PLATELET_HOMEOSTASIS","Platelet homeostasis",64,19,4631,18403,0.212,0.757,0.86,0.9]
[549,"REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS","ABCA transporters in lipid homeostasis",12,13,17439,18403,-0.194,-0.714,0.86,0.9]
[550,"REACTOME_GAB1_SIGNALOSOME","GAB1 signalosome",31,14,6465,18403,0.221,0.712,0.86,0.9]
[551,"REACTOME_PIP3_ACTIVATES_AKT_SIGNALING","PIP3 activates AKT signaling",24,11,6465,18403,0.225,0.694,0.86,0.9]
[552,"REACTOME_PI3K_EVENTS_IN_ERBB2_SIGNALING","PI3K events in ERBB2 signaling",34,15,6619,18403,0.212,0.697,0.87,0.9]
[553,"REACTOME_GAP_JUNCTION_ASSEMBLY","Gap junction assembly",12,3,2245,18403,0.258,0.676,0.88,0.91]
[554,"REACTOME_SIGNALING_BY_NODAL","Signaling by NODAL",13,4,4687,18403,0.249,0.666,0.88,0.92]
[555,"REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES","Transmembrane transport of small molecules",307,63,3133,18403,0.212,0.835,0.9,0.93]
[556,"REACTOME_FRS2_MEDIATED_CASCADE","FRS2-mediated cascade",23,10,6889,18403,0.207,0.632,0.91,0.94]
[557,"REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION","Pre-NOTCH Transcription and Translation",22,10,7847,18403,0.209,0.633,0.91,0.94]
[558,"REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION","Downstream signal transduction",71,29,6206,18403,0.192,0.694,0.91,0.94]
[559,"REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT","ABC-family proteins mediated transport",24,1,90,18403,0.201,0.619,0.92,0.95]
[560,"REACTOME_NGF_SIGNALLING_VIA_TRKA_FROM_THE_PLASMA_MEMBRANE","NGF signalling via TRKA from the plasma membrane",111,49,6816,18403,0.192,0.721,0.92,0.95]
[561,"REACTOME_SIGNALING_BY_EGFR_IN_CANCER","Signaling by EGFR in Cancer",88,39,6673,18403,0.192,0.705,0.93,0.95]
[562,"REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT","Regulation of beta-cell development",19,20,17832,18403,-0.15,-0.651,0.94,0.96]
[563,"REACTOME_CRMPS_IN_SEMA3A_SIGNALING","CRMPs in Sema3A signaling",13,7,7719,18403,0.225,0.6,0.94,0.96]
[564,"REACTOME_PI3K_EVENTS_IN_ERBB4_SIGNALING","PI3K events in ERBB4 signaling",30,12,6465,18403,0.19,0.609,0.94,0.96]
[565,"REACTOME_DARPP_32_EVENTS","DARPP-32 events",16,8,7091,18403,0.21,0.592,0.94,0.96]
[566,"REACTOME_PI_3K_CASCADE","PI-3K cascade",40,17,6889,18403,0.176,0.592,0.95,0.97]
[567,"REACTOME_GENERIC_TRANSCRIPTION_PATHWAY","Generic Transcription Pathway",284,184,10458,18403,0.197,0.777,0.96,0.97]
[568,"REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY","Nuclear Receptor transcription pathway",34,16,8518,18403,0.174,0.571,0.96,0.97]
[569,"REACTOME_DOWNSTREAM_SIGNALING_OF_ACTIVATED_FGFR","Downstream signaling of activated FGFR",71,12,18274,18403,-0.127,-0.771,0.97,0.98]
[570,"REACTOME_CELL_CELL_JUNCTION_ORGANIZATION","Cell-cell junction organization",35,9,4200,18403,0.163,0.539,0.97,0.98]
[571,"REACTOME_SIGNALING_BY_FGFR_IN_DISEASE","Signaling by FGFR in disease",95,38,6687,18403,0.163,0.602,0.98,0.98]
[572,"REACTOME_SIGNALING_BY_FGFR","Signaling by FGFR",82,33,6687,18403,0.154,0.564,0.98,0.99]
[573,"REACTOME_SIGNALING_BY_ERBB2","Signaling by ERBB2",75,31,6673,18403,0.147,0.533,0.99,0.99]
[574,"REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS","Regulation of gene expression in beta cells",13,8,9669,18403,0.173,0.463,0.99,0.99]
[575,"REACTOME_NEURONAL_SYSTEM","Neuronal System",222,126,18402,18403,-0.549,"NA","NA","NA"]