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CARE Checklist of information to include when writing a case report
Topic
Item
Checklist item description
Reported on Line
Title
1
The diagnosis or intervention of primary focus followed by the words “case report” . . . . . . . . . . . . . . . . . . . .1-2. . . . . . .
Key Words
2
2 to 5 key words that identify diagnoses or interventions in this case report, including "case report" . . . 38-39.
Abstract
(no references)
3a
Introduction: What is unique about this case and what does it add to the scientific literature? . . . . . . . . . . .14-18. . . . . .
3b
Main symptoms and/or important clinical findings . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19-23; 24-27.. . . . . .
3c
The main diagnoses, therapeutic interventions, and outcomes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22-32.. . . . . . .
3d
Conclusion—What is the main “take-away” lesson(s) from this case? . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33-37.. . . . . . .
Introduction
4
One or two paragraphs summarizing why this case is unique (may include references) . . . . . . . . . . . . 41-60.
Patient Information
5a
De-identified patient specific information. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 62-70
5b
Primary concerns and symptoms of the patient. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. 62-70. . . . .
5c
Medical, family, and psycho-social history including relevant genetic information . . . . . . . . . . . . . . . . . 62;69
5d
Relevant past interventions with outcomes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 66-68. . . . . . .
6
Describe significant physical examination (PE) and important clinical findings. . . . . . . . . . . . . . . . . . . . . 71-77. . .
7
Historical and current information from this episode of care organized as a timeline . . . . . . . . . . . . . 235 . .
8a
Diagnostic testing (such as PE, laboratory testing, imaging, surveys). . . . . . . . . . . . . . . . . . . . . . . . . . 71-90. . . . .
8b
Diagnostic challenges (such as access to testing, financial, or cultural) . . . . . . . . . . . . . . . . . . . . . . . . . . . 56-60. .
8c
Diagnosis (including other diagnoses considered) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .78-90 ’91-95 . . . . . .
8d
Prognosis (such as staging in oncology) where applicable . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Not applicable . . . . .
9a
Types of therapeutic intervention (such as pharmacologic, surgical, preventive, self-care) . . . . . . . . . . . . 96-103. . . . . . . .
9b
Administration of therapeutic intervention (such as dosage, strength, duration) . . . . . . . . . . . . . . . . . . . . 96-99.. . . . . . . . .
9c
Changes in therapeutic intervention (with rationale) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Not applicable. . . . . .
10a
Clinician and patient-assessed outcomes (if available) . . . . . . . . . . . . . . . . . . . . . . .. . . . . . . . . . . . . . . . . 104-110.. . . . . . . . . . .
10b
Important follow-up diagnostic and other test results . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 100-102; 107-109. . . . . . . . . .
10c
Intervention adherence and tolerability (How was this assessed?) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Not applicable. . . . . . . . .
10d
Adverse and unanticipated events . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Not applicable. . . . . . . . . . . . . .
Clinical Findings
Timeline
Diagnostic
Assessment
Therapeutic
Intervention
Follow-up and
Outcomes
Discussion
11a
A scientific discussion of the strengths AND limitations associated with this case report . . . . . . . . . . . . . . . 136-145;155-162. . . . . . . .
11b
Discussion of the relevant medical literature with references. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 121-128; 155-158.
11c
The scientific rationale for any conclusions (including assessment of possible causes) . . . . . . . . . . . . . . . .136-154 ; 163-175. . . . . . .
11d
The primary “take-away” lessons of this case report (without references) in a one paragraph conclusion . . . 170-175.
Patient Perspective
12
The patient should share their perspective in one to two paragraphs on the treatment(s) they received . . . 212-215 . . . .
Informed Consent
13
Did the patient give informed consent? Please provide if requested . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Yes
No