Method	N	Serum AFP aHR	AFP 95% CI	AFP P-value	Risk Group aHR	Risk Group 95% CI	Risk Group P-value	Conclusion
Complete Case Analysis (primary)	265	0.978	[0.586–1.633]	0.9319	2.143	[1.326–3.462]	0.0018	AFP nonsignificant in all approaches
Mean Imputation	365	0.892	[0.623–1.277]	0.5134	1.992	[1.424–2.786]	<0.0001	AFP nonsignificant; Risk Group robust
MICE (m=5, pooled)	365	—	—	>0.50	1.931	[1.312–2.842]	0.0008	AFP excluded (P>0.5); signature stable
