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["Gene symbol","Gene ID","Description","Biological Process (GO)","Protein Function (Protein Atlas)","Subcellular Location (Protein Atlas)","Drug (DrugBank)"]
["MDC1","9656","mediator of DNA damage checkpoint 1","GO:0031573 intra-S DNA damage checkpoint;GO:0006303 double-strand break repair via nonhomologous end joining;GO:0044773 mitotic DNA damage checkpoint","Cancer-related genes:Mutational cancer driver genes; Predicted intracellular proteins","Nuclear bodies (Supported); Additional: Nucleoplasm"]
["PARP3","10039","poly(ADP-ribose) polymerase family member 3","GO:1905662 negative regulation of telomerase RNA reverse transcriptase activity;GO:0030592 DNA ADP-ribosylation;GO:1905661 regulation of telomerase RNA reverse transcriptase activity","ENZYME proteins:Transferases; Enzymes; FDA approved drug targets:Small molecule drugs; Predicted intracellular proteins","Nuclear bodies;Nucleoplasm (Supported)","2-methyl-3,5,7,8-tetrahydro-4H-thiopyrano[4,3-d]pyrimidin-4-one; 4-[3-(1,4-diazepan-1-ylcarbonyl)-4-fluorobenzyl]phthalazin-1(2H)-one; N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE; Olaparib; Rucaparib"]
["PSMB1","5689","proteasome 20S subunit beta 1","GO:0010499 proteasomal ubiquitin-independent protein catabolic process;GO:0006521 regulation of cellular amino acid metabolic process;GO:1902036 regulation of hematopoietic stem cell differentiation","Peptidases:Threonine-type peptidases; ENZYME proteins:Hydrolases; Enzymes; FDA approved drug targets:Small molecule drugs; Predicted intracellular proteins","Nucleoplasm (Supported)","Bortezomib; (3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE; Carfilzomib"]
["PSMB9","5698","proteasome 20S subunit beta 9","GO:0010499 proteasomal ubiquitin-independent protein catabolic process;GO:0006521 regulation of cellular amino acid metabolic process;GO:1902036 regulation of hematopoietic stem cell differentiation","Peptidases:Threonine-type peptidases; ENZYME proteins:Hydrolases; Enzymes; FDA approved drug targets:Small molecule drugs; Predicted intracellular proteins","Cytosol (Supported)","Carfilzomib"]
["PSMD2","5708","proteasome 26S subunit, non-ATPase 2","GO:0006521 regulation of cellular amino acid metabolic process;GO:1902036 regulation of hematopoietic stem cell differentiation;GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent","Predicted intracellular proteins"]
["PSMD7","5713","proteasome 26S subunit, non-ATPase 7","GO:0006521 regulation of cellular amino acid metabolic process;GO:1902036 regulation of hematopoietic stem cell differentiation;GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent","Enzymes; Peptidases:Metallopeptidases; Predicted intracellular proteins","Nucleoplasm (Enhanced)"]
["PSMD14","10213","proteasome 26S subunit, non-ATPase 14","GO:0070536 protein K63-linked deubiquitination;GO:0006521 regulation of cellular amino acid metabolic process;GO:1902036 regulation of hematopoietic stem cell differentiation","Enzymes; Peptidases:Metallopeptidases; Predicted intracellular proteins","Nucleoplasm (Supported)"]