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["DOI/PMID","Bibliography"]
["https://doi.org/10.1002/jcp.24557","Vimalraj S, Partridge NC, Selvamurugan N. A positive role of microRNA‐15b on regulation of osteoblast differentiation. Journal of cellular physiology. 2014 Sep;229(9):1236-44."]
["https://www.ncbi.nlm.nih.gov/pubmed/26469406","Wang Z, Xie Q, Yu Z, Zhou H, Huang Y, Bi X, Wang Y, Shi W, Sun H, Gu P, Fan X. A regulatory loop containing miR-26a, GSK3β and C/EBPα regulates the osteogenesis of human adipose-derived mesenchymal stem cells. Scientific reports. 2015 Oct 15;5(1):1-8."]
["https://www.ncbi.nlm.nih.gov/pubmed/27158337","Xia Z, Ma P, Wu N, Su X, Chen J, Jiang C, Liu S, Chen W, Ma B, Yang X, Ma Y. Altered function in cartilage derived mesenchymal stem cell leads to OA-related cartilage erosion. American journal of translational research. 2016;8(2):433."]
["https://doi.org/10.1371/journal.pone.0114627","Xu JF, Yang GH, Pan XH, Zhang SJ, Zhao C, Qiu BS, Gu HF, Hong JF, Cao L, Chen Y, Xia B. Altered microRNA expression profile in exosomes during osteogenic differentiation of human bone marrow-derived mesenchymal stem cells. PloS one. 2014 Dec 11;9(12):e114627."]
["https://doi.org/10.1177/2041731418794007","Waddell SJ, de Andrés MC, Tsimbouri PM, Alakpa EV, Cusack M, Dalby MJ, Oreffo RO. Biomimetic oyster shell–replicated topography alters the behaviour of human skeletal stem cells. Journal of tissue engineering. 2018 Aug;9:2041731418794007."]
["https://doi.org/10.1038/srep21961","Qin Y, Wang L, Gao Z, Chen G, Zhang C. Bone marrow stromal/stem cell-derived extracellular vesicles regulate osteoblast activity and differentiation in vitro and promote bone regeneration in vivo. Scientific reports. 2016 Feb 25;6(1):1-1."]
["https://doi.org/10.1186/1471-2350-15-45","Kaneto CM, Lima PS, Zanette DL, Prata KL, Neto JM, de Paula FJ, Silva WA. COL1A1 and miR-29b show lower expression levels during osteoblast differentiation of bone marrow stromal cells from Osteogenesis Imperfecta patients. BMC medical genetics. 2014 Dec;15(1):1-5."]
["https://doi.org/10.1155/2018/9015758","Wei B, Wei W, Wang L, Zhao B. Differentially expressed micrornas in conservatively treated nontraumatic osteonecrosis compared with healthy controls. BioMed research international. 2018 May 24;2018"]
["https://doi.org/10.1155/2016/8169614","Bolamperti S, Villa I, Spinello A, Manfredini G, Mrak E, Mezzadri U, Ometti M, Fraschini G, Guidobono F, Rubinacci A. Evidence for Altered Canonical Wnt Signaling in the Trabecular Bone of Elderly Postmenopausal Women with Fragility Femoral Fracture. BioMed research international. 2016 Nov 24;2016."]
["https://doi.org/10.1016/j.amjms.2017.11.003","Ni Z, Shang X, Tang G, Niu L. Expression of miR-206 in human knee articular chondrocytes and effects of miR-206 on proliferation and apoptosis of articular chondrocytes. The American journal of the medical sciences. 2018 Mar 1;355(3):240-6."]
["https://doi.org/10.1016/j.ejcb.2017.07.002","Du K, Li Z, Fang X, Cao T, Xu Y. Ferulic acid promotes osteogenesis of bone marrow-derived mesenchymal stem cells by inhibiting microRNA-340 to induce β-catenin expression through hypoxia. European journal of cell biology. 2017 Sep 1;96(6):496-503."]
["http://www.rnajournal.org/cgi/doi/10.1261/rna.049148.114","Laxman N, Rubin CJ, Mallmin H, Nilsson O, Pastinen T, Grundberg E, Kindmark A. Global miRNA expression and correlation with mRNA levels in primary human bone cells. Rna. 2015 Aug 1;21(8):1433-43."]
["https://doi.org/10.1038/s12276-018-0048-7","Liu GX, Ma S, Li Y, Yu Y, Zhou YX, Lu YD, Jin L, Wang ZL, Yu JH. Hsa-let-7c controls the committed differentiation of IGF-1-treated mesenchymal stem cells derived from dental pulps by targeting IGF-1R via the MAPK pathways. Experimental & molecular medicine. 2018 Apr 13;50(4):1-4."]
["PMID: 29218085","Gu H, Xu J, Huang Z, Wu L, Zhou K, Zhang Y, Chen J, Xia J, Yin X. Identification and differential expression of microRNAs in 1, 25-dihydroxyvitamin D3-induced osteogenic differentiation of human adipose-derived mesenchymal stem cells. American journal of translational research. 2017;9(11):4856."]
["https://doi.org/10.2147/IJN.S104851","Wang Z, Wu G, Wei M, Liu Q, Zhou J, Qin T, Feng X, Liu H, Feng Z, Zhao Y. Improving the osteogenesis of human bone marrow mesenchymal stem cell sheets by microRNA-21-loaded chitosan/hyaluronic acid nanoparticles via reverse transfection. International journal of nanomedicine. 2016;11:2091"]
["https://doi.org/10.1016/j.jos.2016.07.021","Yoshizuka M, Nakasa T, Kawanishi Y, Hachisuka S, Furuta T, Miyaki S, Adachi N, Ochi M. Inhibition of microRNA-222 expression accelerates bone healing with enhancement of osteogenesis, chondrogenesis, and angiogenesis in a rat refractory fracture model. Journal of Orthopaedic Science. 2016 Nov 1;21(6):852-8."]
["https://doi.org/10.1016/j.omtn.2018.03.004","Feng L, Shi L, Lu YF, Wang B, Tang T, Fu WM, He W, Li G, Zhang JF. Linc-ROR promotes osteogenic differentiation of mesenchymal stem cells by functioning as a competing endogenous RNA for miR-138 and miR-145. Molecular Therapy-Nucleic Acids. 2018 Jun 1;11:345-53."]
["https://doi.org/10.1111/cid.12553","Peng W, Zhu SX, Wang J, Chen LL, Weng JQ, Chen SL. Lnc‐NTF3‐5 promotes osteogenic differentiation of maxillary sinus membrane stem cells via sponging miR‐93‐3p. Clinical implant dentistry and related research. 2018 Apr;20(2):110-21."]
["https://doi.org/10.1016/j.biopha.2017.02.090","Wang Q, Li Y, Zhang Y, Ma L, Lin L, Meng J, Jiang L, Wang L, Zhou P, Zhang Y. LncRNA MEG3 inhibited osteogenic differentiation of bone marrow mesenchymal stem cells from postmenopausal osteoporosis by targeting miR-133a-3p. Biomedicine & Pharmacotherapy. 2017 May 1;89:1178-86."]
["https://doi.org/10.1371/journal.pone.0169097","Wei B, Wei W, Zhao B, Guo X, Liu S. Long non-coding RNA HOTAIR inhibits miR-17-5p to regulate osteogenic differentiation and proliferation in non-traumatic osteonecrosis of femoral head. PloS one. 2017 Feb 16;12(2):e0169097."]
["https://doi.org/10.1002/term.435","Mariner PD, Johannesen E, Anseth KS. Manipulation of miRNA activity accelerates osteogenic differentiation of hMSCs in engineered 3D scaffolds. Journal of tissue engineering and regenerative medicine. 2012 Apr;6(4):314-24."]
["https://doi.org/10.2147/IJN.S94689","Wang Z, Wu G, Feng Z, Bai S, Dong Y, Wu G, Zhao Y. Microarc-oxidized titanium surfaces functionalized with microRNA-21-loaded chitosan/hyaluronic acid nanoparticles promote the osteogenic differentiation of human bone marrow mesenchymal stem cells. International journal of nanomedicine. 2015;10:6675."]
["https://doi.org/10.1016/j.gene.2013.06.021","Baglìo SR, Devescovi V, Granchi D, Baldini N. MicroRNA expression profiling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-31. Gene. 2013 Sep 15;527(1):321-31."]
["https://doi.org/10.3892/mmr.2014.2024","Chen S, Yang L, Jie Q, Lin YS, Meng GL, Fan JZ, Zhang JK, Fan J, Luo ZJ, Liu J. MicroRNA‑125b suppresses the proliferation and osteogenic differentiation of human bone marrow‑derived mesenchymal stem cells. Molecular medicine reports. 2014 May 1;9(5):1820-6."]
["https://doi.org/10.1371/journal.pone.0098063","Cheung KS, Sposito N, Stumpf PS, Wilson DI, Sanchez-Elsner T, Oreffo RO. MicroRNA-146a regulates human foetal femur derived skeletal stem cell differentiation by down-regulating SMAD2 and SMAD3. PloS one. 2014 Jun 3;9(6):e98063."]
["https://doi.org/10.1002/jor.22884","Meng YB, Li X, Li ZY, Zhao J, Yuan XB, Ren Y, Cui ZD, Liu YD, Yang XJ. microRNA‐21 promotes osteogenic differentiation of mesenchymal stem cells by the PI3K/β‐catenin pathway. Journal of Orthopaedic Research. 2015 Jul;33(7):957-64."]
["https://doi.org/10.1038/s41598-017-16720-8","Wei F, Yang S, Guo Q, Zhang X, Ren D, Lv T, Xu X. MicroRNA-21 regulates osteogenic differentiation of periodontal ligament stem cells by targeting Smad5. Scientific reports. 2017 Nov 30;7(1):1-2."]
["https://www.ncbi.nlm.nih.gov/pubmed/28123639","Zhang Y, Gao Y, Cai L, Li F, Lou Y, Xu N, Kang Y, Yang H. MicroRNA-221 is involved in the regulation of osteoporosis through regulates RUNX2 protein expression and osteoblast differentiation. American journal of translational research. 2017;9(1):126."]
["https://doi.org/10.1016/j.biocel.2016.01.004","Li T, Li H, Wang Y, Li T, Fan J, Xiao K, Zhao RC, Weng X. microRNA-23a inhibits osteogenic differentiation of human bone marrow-derived mesenchymal stem cells by targeting LRP5. The international journal of biochemistry & cell biology. 2016 Mar 1;72:55-62."]
["https://doi.org/10.1111/jcmm.12961","Zhang GP, Zhang J, Zhu CH, Lin L, Wang J, Zhang HJ, Li J, Yu XG, Zhao ZS, Dong W, Liu GB. Micro RNA‐98 regulates osteogenic differentiation of human bone mesenchymal stromal cells by targeting BMP 2. Journal of cellular and molecular medicine. 2017 Feb;21(2):254-64."]
["https://doi.org/10.1186/1471-2164-14-111","Trompeter HI, Dreesen J, Hermann E, Iwaniuk KM, Hafner M, Renwick N, Tuschl T, Wernet P. MicroRNAs miR-26a, miR-26b, and miR-29b accelerate osteogenic differentiation of unrestricted somatic stem cells from human cord blood. BMC genomics. 2013 Dec;14(1):1-3."]
["https://doi.org/10.1002/jcb.24144","Laine SK, Alm JJ, Virtanen SP, Aro HT, Laitala‐Leinonen TK. MicroRNAs miR‐96, miR‐124, and miR‐199a regulate gene expression in human bone marrow‐derived mesenchymal stem cells. Journal of cellular biochemistry. 2012 Aug;113(8):2687-95."]
["https://doi.org/10.1038/srep36988","Wang H, Meng Y, Cui Q, Qin F, Yang H, Chen Y, Cheng Y, Shi J, Guo Y. MiR-101 targets the EZH2/Wnt/β-catenin the pathway to promote the osteogenic differentiation of human bone marrow-derived mesenchymal stem cells. Scientific reports. 2016 Nov 15;6(1):1-0."]
["https://doi.org/10.1002/jcp.24402","Li J, Dong J, Zhang ZH, Zhang DC, You XY, Zhong Y, Chen MS, Liu SM. miR‐10a restores human mesenchymal stem cell differentiation by repressing KLF4. Journal of cellular physiology. 2013 Dec;228(12):2324-36."]
["https://doi.org/10.1016/j.febslet.2014.05.048","Hwang S, Park SK, Lee HY, Kim SW, Lee JS, Choi EK, You D, Kim CS, Suh N. miR-140-5p suppresses BMP2-mediated osteogenesis in undifferentiated human mesenchymal stem cells. FEBS letters. 2014 Aug 25;588(17):2957-63."]
["https://doi.org/10.1016/j.febslet.2014.03.057","Huszar JM, Payne CJ. MIR146A inhibits JMJD3 expression and osteogenic differentiation in human mesenchymal stem cells. FEBS letters. 2014 May 2;588(9):1850-6."]
["https://doi.org/10.1093/nar/gkt666","Hsieh JY, Huang TS, Cheng SM, Lin WS, Tsai TN, Lee OK, Wang HW. miR-146a-5p circuitry uncouples cell proliferation and migration, but not differentiation, in human mesenchymal stem cells. Nucleic acids research. 2013 Nov 1;41(21):9753-63."]
["https://doi.org/10.1002/stem.728","Liu Y, Liu W, Hu C, Xue Z, Wang G, Ding B, Luo H, Tang L, Kong X, Chen X, Liu N. MiR‐17 modulates osteogenic differentiation through a coherent feed‐forward loop in mesenchymal stem cells isolated from periodontal ligaments of patients with periodontitis. Stem cells. 2011 Nov;29(11):1804-16."]
["https://doi.org/10.1038/emm.2014.43","Jia J, Feng X, Xu W, Yang S, Zhang Q, Liu X, Feng Y, Dai Z. MiR-17-5p modulates osteoblastic differentiation and cell proliferation by targeting SMAD7 in non-traumatic osteonecrosis. Experimental & molecular medicine. 2014 Jul;46(7):e107-."]
["https://doi.org/10.1038/srep46136","Zhu S, Peng W, Li X, Weng J, Zhang X, Guo J, Huang D, Rong Q, Chen S. miR-1827 inhibits osteogenic differentiation by targeting IGF1 in MSMSCs. Scientific reports. 2017 Apr 7;7(1):1-2."]
["https://doi.org/10.1111/jcmm.13047","Qu X, Chen Z, Fan D, Sun C, Zeng Y, Guo Z, Qi Q, Li W. MiR‐199b‐5p inhibits osteogenic differentiation in ligamentum flavum cells by targeting JAG1 and modulating the Notch signalling pathway. Journal of cellular and molecular medicine. 2017 Jun;21(6):1159-70."]
["https://doi.org/10.1002/jcb.24479","Mei Y, Bian C, Li J, Du Z, Zhou H, Yang Z, Zhao RC. miR‐21 modulates the ERK–MAPK signaling pathway by regulating SPRY2 expression during human mesenchymal stem cell differentiation. Journal of cellular biochemistry. 2013 Jun;114(6):1374-84."]
["https://doi.org/10.3892/mmr.2017.7821","Cao F, Zhan J, Chen X, Zhang K, Lai R, Feng Z. miR-214 promotes periodontal ligament stem cell osteoblastic differentiation by modulating Wnt/β‑catenin signaling. Molecular medicine reports. 2017 Dec 1;16(6):9301-8."]
["https://doi.org/10.1038/nm.3026","Wang X, Guo B, Li Q, Peng J, Yang Z, Wang A, Li D, Hou Z, Lv K, Kan G, Cao H. miR-214 targets ATF4 to inhibit bone formation. Nature medicine. 2013 Jan;19(1):93-100."]
["https://doi.org/10.1038/cdd.2015.99","Li H, Li T, Fan J, Fan L, Wang S, Weng X, Han Q, Zhao RC. miR-216a rescues dexamethasone suppression of osteogenesis, promotes osteoblast differentiation and enhances bone formation, by regulating c-Cbl-mediated PI3K/AKT pathway. Cell Death & Differentiation. 2015 Dec;22(12):1935-45."]
["https://doi.org/10.1159/000445621","You L, Pan L, Chen L, Gu W, Chen J. MiR-27a is essential for the shift from osteogenic differentiation to adipogenic differentiation of mesenchymal stem cells in postmenopausal osteoporosis. Cellular Physiology and Biochemistry. 2016;39(1):253-65."]
["https://doi.org/10.1038/cdd.2010.167","Tomé M, López-Romero P, Albo C, Sepúlveda JC, Fernández-Gutiérrez B, Dopazo A, Bernad A, González MA. miR-335 orchestrates cell proliferation, migration and differentiation in human mesenchymal stem cells. Cell Death & Differentiation. 2011 Jun;18(6):985-95."]
["https://doi.org/10.1002/1873-3468.12064","Mi W, Shi Q, Chen X, Wu T, Huang H. miR‐33a‐5p modulates TNF‐α‐inhibited osteogenic differentiation by targeting SATB 2 expression in h BMSC s. FEBS letters. 2016 Feb;590(3):396-407."]
["https://doi.org/10.1371/journal.pone.0072266","Wang Q, Cai J, Cai X-h, Chen L (2013) miR-346 Regulates Osteogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells by Targeting the Wnt/b-Catenin Pathway. PLoS ONE 8(9): e72266"]
["https://doi.org/10.1016/j.stemcr.2016.06.010","Fan C, Jia L, Zheng Y, Jin C, Liu Y, Liu H, Zhou Y. MiR-34a promotes osteogenic differentiation of human adipose-derived stem cells via the RBP2/NOTCH1/CYCLIN D1 coregulatory network. Stem cell reports. 2016 Aug 9;7(2):236-48."]
["https://doi.org/10.1038/srep22599","Hao C, Yang S, Xu W, Shen JK, Ye S, Liu X, Dong Z, Xiao B, Feng Y. MiR-708 promotes steroid-induced osteonecrosis of femoral head, suppresses osteogenic differentiation by targeting SMAD3. Scientific reports. 2016 Mar 2;6(1):1-3."]
["https://doi.org/10.1111/1440-1681.12912","Liu H, Liu Q, Wu XP, He HB, Fu L. MiR‐96 regulates bone metabolism by targeting osterix. Clinical and Experimental Pharmacology and Physiology. 2018 Jun;45(6):602-13."]
["https://doi.org/10.1186/s13018-017-0542-y","Kopańska M, Szala D, Czech J, Gabło N, Gargasz K, Trzeciak M, Zawlik I, Snela S. MiRNA expression in the cartilage of patients with osteoarthritis. Journal of orthopaedic surgery and research. 2017 Dec;12(1):1-7."]
["https://doi.org/10.1371/journal.pone.0013558","He J, Zhang JF, Yi C, Lv Q, Xie WD, Li JN, Wan G, Cui K, Kung HF, Yang J, Yang BB. miRNA-mediated functional changes through co-regulating function related genes. PloS one. 2010 Oct 22;5(10):e13558."]
["https://doi.org/10.1038/s41419-018-0480-6","Li L, Liu W, Wang H, Yang Q, Zhang L, Jin F, Jin Y. Mutual inhibition between HDAC9 and miR-17 regulates osteogenesis of human periodontal ligament stem cells in inflammatory conditions. Cell death & disease. 2018 Apr 24;9(5):1-1."]
["https://doi.org/10.1038/srep27941","Castaño IM, Curtin CM, Duffy GP, O’Brien FJ. Next generation bone tissue engineering: non-viral miR-133a inhibition using collagen-nanohydroxyapatite scaffolds rapidly enhances osteogenesis. Scientific Reports. 2016 Jun 14;6(1):1-0."]
["https://doi.org/10.1182/blood-2014-02-558007","Reagan MR, Mishima Y, Glavey SV, Zhang Y, Manier S, Lu ZN, Memarzadeh M, Zhang Y, Sacco A, Aljawai Y, Shi J. Investigating osteogenic differentiation in multiple myeloma using a novel 3D bone marrow niche model. Blood. 2014 Nov 20;124(22):3250-9."]
["https://doi.org/10.1155/2016/6465307","Glemžaitė M, Navakauskienė R. Osteogenic differentiation of human amniotic fluid mesenchymal stem cells is determined by epigenetic changes. Stem cells international. 2016 Oct 12;2016."]
["https://doi.org/10.1590/1414-431X20132896","Pinto MT, Nicolete LD, Rodrigues ES, Palma PV, Orellana MD, Kashima S, Covas DT. Overexpression of hsa-miR-125b during osteoblastic differentiation does not influence levels of Runx2, osteopontin, and ALPL gene expression. Brazilian Journal of Medical and Biological Research. 2013 Aug;46(8):676-80."]
["https://doi.org/10.3892/ijmm.2015.2273","Bian Y, Qian W, Li H, Zhao RC, Shan WX, Weng X. Pathogenesis of glucocorticoid-induced avascular necrosis: a microarray analysis of gene expression in vitro. International journal of molecular medicine. 2015 Sep 1;36(3):678-84."]
["https://doi.org/10.1016/j.stemcr.2017.01.028","Chen SI, Zheng Y, Zhang S, Jia L, Zhou Y. Promotion effects of miR-375 on the osteogenic differentiation of human adipose-derived mesenchymal stem cells. Stem Cell Reports. 2017 Mar 14;8(3):773-86."]
["https://doi.org/10.1186/s12891-015-0652-9","Tornero-Esteban P, Rodríguez-Rodríguez L, Abásolo L, Tomé M, López-Romero P, Herranz E, González MA, Marco F, Moro E, Fernández-Gutiérrez B, Lamas JR. Signature of microRNA expression during osteogenic differentiation of bone marrow MSCs reveals a putative role of miR-335-5p in osteoarthritis. BMC musculoskeletal disorders. 2015 Dec;16(1):1-9."]
["https://doi.org/10.5966/sctm.2013-0081","Trohatou O, Zagoura D, Bitsika V, Pappa KI, Antsaklis A, Anagnou NP, Roubelakis MG. Sox2 suppression by miR‐21 governs human mesenchymal stem cell properties. Stem cells translational medicine. 2014 Jan;3(1):54-68."]
["https://doi.org/10.1371/journal.pone.0062582","Guerit D, Philipot D, Chuchana P, Toupet K, Brondello JM, Mathieu M, Jorgensen C, Noel D. Sox9-regulated miRNA-574-3p inhibits chondrogenic differentiation of mesenchymal stem cells. PloS one. 2013 Apr 23;8(4):e62582."]
["https://doi.org/10.1016/j.biomaterials.2014.04.048","Nguyen MK, Jeon O, Krebs MD, Schapira D, Alsberg E. Sustained localized presentation of RNA interfering molecules from in situ forming hydrogels to guide stem cell osteogenic differentiation. Biomaterials. 2014 Aug 1;35(24):6278-86."]
["https://doi.org/10.1155/2015/309747","Zhang W, Zhang L, Zhou Y, Ji X, Liu J, Liu D, Yin P, Peng Y, Hao M, Zhang L, Tang P. Synergistic effects of BMP9 and miR-548d-5p on promoting osteogenic differentiation of mesenchymal stem cells. BioMed research international. 2015 Nov 1;2015."]
["https://doi.org/10.1038/cddis.2013.65","Liu W, Liu Y, Guo T, Hu C, Luo H, Zhang L, Shi S, Cai T, Ding Y, Jin Y. TCF3, a novel positive regulator of osteogenesis, plays a crucial role in miR-17 modulating the diverse effect of canonical Wnt signaling in different microenvironments. Cell death & disease. 2013 Mar;4(3):e539-."]
["https://doi.org/10.1155/2017/7257628","Manochantr S, Marupanthorn K, Tantrawatpan C, Kheolamai P, Tantikanlayaporn D, Sanguanjit P. The effects of BMP-2, miR-31, miR-106a, and miR-148a on osteogenic differentiation of MSCs derived from amnion in comparison with MSCs derived from the bone marrow. Stem cells international. 2017 Jan 1;2017."]
["https://doi.org/10.1016/j.bone.2013.07.016","Hong IS, Lee HY, Choi SW, Kim HS, Yu KR, Seo Y, Jung JW, Kang KS. The effects of hedgehog on RNA binding protein Msi1 during the osteogenic differentiation of human cord blood-derived mesenchymal stem cells. Bone. 2013 Oct 1;56(2):416-25."]
["https://doi.org/10.1038/s41598-018-27514-x","Xu C, Zhang H, Gu W, Wu H, Chen Y, Zhou W, Sun B, Shen X, Zhang Z, Wang Y, Liu Y. The microRNA-10a/ID3/RUNX2 axis modulates the development of ossification of posterior longitudinal ligament. Scientific reports. 2018 Jun 15;8(1):1-3."]
["https://doi.org/10.1002/jbmr.1798","Yang N, Wang G, Hu C, Shi Y, Liao L, Shi S, Cai Y, Cheng S, Wang X, Liu Y, Tang L. Tumor necrosis factor α suppresses the mesenchymal stem cell osteogenesis promoter miR‐21 in estrogen deficiency–induced osteoporosis. Journal of Bone and Mineral Research. 2013 Mar;28(3):559-73."]
["https://doi.org/10.1371/journal.pone.0079752","Xu S, Santini GC, De Veirman K, Broek IV, Leleu X, De Becker A, Van Camp B, Vanderkerken K, Van Riet I. Upregulation of miR-135b is involved in the impaired osteogenic differentiation of mesenchymal stem cells derived from multiple myeloma patients. PloS one. 2013 Nov 6;8(11):e79752."]
["https://doi.org/10.3892/mmr.2017.6308","Zhang Y, Weng S, Yin J, Ding H, Zhang C, Gao Y. Vitamin K2 promotes mesenchymal stem cell differentiation by inhibiting miR‑133a expression. Molecular medicine reports. 2017 May 1;15(5):2473-80."]
["https://doi.org/10.3390/ijms13022063","Song H, Wang Q, Wen J, Liu S, Gao X, Cheng J, Zhang D. ACVR1, a therapeutic target of fibrodysplasia ossificans progressiva, is negatively regulated by miR-148a. International journal of molecular sciences. 2012 Feb;13(2):2063-77."]
["https://doi.org/10.1186/s12860-015-0057-5","Martin PJ, Haren N, Ghali O, Clabaut A, Chauveau C, Hardouin P, Broux O. Adipogenic RNAs are transferred in osteoblasts via bone marrow adipocytes-derived extracellular vesicles (EVs). BMC cell biology. 2015 Dec;16(1):1-0."]
["https://doi.org/10.1016/j.bbrc.2014.04.091","Qu B, Xia X, Wu HH, Tu CQ, Pan XM. PDGF-regulated miRNA-138 inhibits the osteogenic differentiation of mesenchymal stem cells. Biochemical and biophysical research communications. 2014 Jun 6;448(3):241-7."]
["https://doi.org/10.1007/s10735-015-9628-1","Zhang R, Weng Y, Li B, Jiang Y, Yan S, He F, Chen X, Deng F, Wang J, Shi Q. BMP9-induced osteogenic differentiation is partially inhibited by miR-30a in the mesenchymal stem cell line C3H10T1/2. Journal of molecular histology. 2015 Oct;46(4):399-407"]
["https://doi.org/10.1371/journal.pone.0160517","Peffers MJ, Goljanek-Whysall K, Collins J, Fang Y, Rushton M, Loughlin J, Proctor C, Clegg PD. Decoding the regulatory landscape of ageing in musculoskeletal engineered tissues using genome-wide DNA methylation and RNASeq. PloS one. 2016 Aug 17;11(8):e0160517."]
["https://doi.org/10.1016/j.bbrc.2014.02.058","Xie Q, Wang Z, Bi X, Zhou H, Wang Y, Gu P, Fan X. Effects of miR-31 on the osteogenesis of human mesenchymal stem cells. Biochemical and biophysical research communications. 2014 Mar 28;446(1):98-104."]
["https://doi.org/10.1016/j.bone.2017.12.013","Wu J, Zhao J, Sun L, Pan Y, Wang H, Zhang WB. Long non-coding RNA H19 mediates mechanical tension-induced osteogenesis of bone marrow mesenchymal stem cells via FAK by sponging miR-138. Bone. 2018 Mar 1;108:62-70."]
["https://doi.org/10.1016/j.bone.2017.12.013","Wu J, Zhao J, Sun L, Pan Y, Wang H, Zhang WB. Long non-coding RNA H19 mediates mechanical tension-induced osteogenesis of bone marrow mesenchymal stem cells via FAK by sponging miR-138. Bone. 2018 Mar 1;108:62-70."]
["https://doi.org/10.1073/pnas.1016758108 ","Eskildsen T, Taipaleenmäki H, Stenvang J, Abdallah BM, Ditzel N, Nossent AY, Bak M, Kauppinen S, Kassem M. MicroRNA-138 regulates osteogenic differentiation of human stromal (mesenchymal) stem cells in vivo. Proceedings of the National Academy of Sciences. 2011 Apr 12;108(15):6139-44."]
["https://doi.org/10.1002/stem.1699","Tomé M, Sepúlveda JC, Delgado M, Andrades JA, Campisi J, González MA, Bernad A. miR‐335 correlates with senescence/aging in human mesenchymal stem cells and inhibits their therapeutic actions through inhibition of AP‐1 activity. Stem Cells. 2014 Aug;32(8):2229-44."]
["https://doi.org/10.1038/cddis.2014.462","Hamam D, Ali D, Vishnubalaji R, Hamam R, Al-Nbaheen M, Chen L, Kassem M, Aldahmash A, Alajez NM. microRNA-320/RUNX2 axis regulates adipocytic differentiation of human mesenchymal (skeletal) stem cells. Cell death & disease. 2014 Oct;5(10):e1499-."]
["https://doi.org/10.1080/10799893.2016.1212375","Zhang W, Yao C, Wei Z, Dong Q. miR-128 promoted adipogenic differentiation and inhibited osteogenic differentiation of human mesenchymal stem cells by suppression of VEGF pathway. Journal of Receptors and Signal Transduction. 2017 May 4;37(3):217-23."]
["https://doi.org/10.1016/j.bbrc.2016.08.160","Wu S, Liu W, Zhou L. MiR-590-3p regulates osteogenic differentiation of human mesenchymal stem cells by regulating APC gene. Biochemical and biophysical research communications. 2016 Sep 30;478(4):1582-7."]
["https://doi.org/10.1002/jcp.22024","Cho HH, Shin KK, Kim YJ, Song JS, Kim JM, Bae YC, Kim CD, Jung JS. NF‐κB activation stimulates osteogenic differentiation of mesenchymal stem cells derived from human adipose tissue by increasing TAZ expression. Journal of cellular physiology. 2010 Apr;223(1):168-77."]

{"sheet":"DEVID data","index":1,"n_rows":549,"n_cols":32,"rows_kept":549,"flags":["formulas_cached_only"]}
["miR",null,"Target gene","Cell cycle","Proliferation","Wnt regulation","BMP regulation","Hippo regulation","SMAD regulation","MAPK regulation","Notch regulation","Differentiation","Osteo differentiation/ossification/bone formation","Organism development (in general or different cells/tissues/organs)","Apoptosis ","Representative transcript","Gene name","3P-seq tags + 5","Conserved sites total","Conserved 8mer sites","Conserved 7mer-m8 sites","Conserved 7mer-A1 sites","Poorly conserved sites total","Poorly conserved 8mer sites","Poorly conserved 7mer-m8 sites","Poorly conserved 7mer-A1 sites","6mer sites","Representative miRNA","Cumulative weighted context++ score","Total context++ score","Aggregate PCT","Previous TargetScan publication(s)\n"]
["mir-29b","miR-29-3p ","ABHD5","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000458276.2","abhydrolase domain containing 5 ",884,2,0,0,2,1,1,0,0,0,"hsa-miR-29a-3p",-0.35,-0.83,0.98,2011]
["let-7a/let-7c","let-7-5p/98-5p","ABL2","no data","+","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000502732.1","c-abl oncogene 2, non-receptor tyrosine kinase ",892,2,1,0,1,0,0,0,0,1,"hsa-let-7d-5p",-0.34,-0.36,"> 0.99","2009, 2011\n"]
["miR-125-5p","miR-125-5p","ABL2","no data","+","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000502732.1","c-abl oncogene 2, non-receptor tyrosine kinase ",892,2,0,2,0,1,0,0,1,5,"hsa-miR-125a-5p",-0.13,-0.13,0.77,"2009, 2011\n"]
["mir-17","miR-17-5p/20-5p/93-5p/106-5p/519-3p","ABL2","no data","+","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000502732.1","c-abl oncogene 2, non-receptor tyrosine kinase ",892,2,0,2,0,5,0,4,1,2,"hsa-miR-20a-5p",-0.28,-0.29,0.9,"2009, 2011\n"]
["mir-26a","miR-26-5p  ","ABL2","no data","+","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000502732.1","c-abl oncogene 2, non-receptor tyrosine kinase ",892,3,1,1,1,2,0,0,2,4,"hsa-miR-26a-5p",-0.25,-0.26,0.96,"2009, 2011\n"]
["mir-31/31-5p","miR-31-5p","ABL2","no data","+","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000502732.1","c-abl oncogene 2, non-receptor tyrosine kinase ",892,2,0,2,0,0,0,0,0,1,"hsa-miR-31-5p",-0.08,-0.09,0.52,"\n"]
["miR-125-5p","miR-125-5p","ACHE","no data","+","no data","no data","no data","no data","no data","no data","no data","+","+","no data","ENST00000302913.4","acetylcholinesterase ",14,2,2,0,0,0,0,0,0,1,"hsa-miR-125b-5p",-0.68,-0.71,0.8,"2009, 2011\n"]
["mir-146b-5p","mir-146b-5p","ACKR2","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000442925.1","atypical chemokine receptor 2 ",5,2,2,0,0,0,0,0,0,0,"hsa-miR-146a-5p",-0.38,-0.38,"< 0.1","2009, 2011\n"]
["miR-125-5p","miR-125-5p","ACVR1C","no data","+","no data","no data","no data","no data","no data","no data","+","no data","no data","+","ENST00000243349.8","activin A receptor, type IC ",27,2,1,1,0,0,0,0,0,0,"hsa-miR-125a-5p",-0.21,-0.28,0.79,"2009, 2011\n"]
["mir-23b","miR-23-3p      ","ACVR1C","no data","+","no data","no data","no data","no data","no data","no data","+","no data","no data","+","ENST00000243349.8","activin A receptor, type IC ",27,2,0,1,1,2,0,0,2,3,"hsa-miR-23b-3p",-0.43,-0.49,0.43,"2009, 2011\n"]
["let-7a/let-7c","let-7-5p/98-5p","ACVR2A","no data","no data","no data","+","no data","+","no data","no data","+","+","+","no data","ENST00000241416.7","activin A receptor, type IIA ",109,2,0,0,2,0,0,0,0,1,"hsa-let-7d-5p",-0.13,-0.62,0.99,"2007, 2009, 2011\n"]
["let-7a/let-7c","let-7-5p/98-5p","ACVR2B","no data","no data","no data","+","no data","no data","no data","no data","+","+","+","no data","ENST00000352511.4","activin A receptor, type IIB ",21,2,0,0,2,0,0,0,0,0,"hsa-let-7d-5p",-0.25,-0.62,"> 0.99","2007, 2009, 2011\n"]
["miR-101","miR-101-3p.1  ","ACVR2B","no data","no data","no data","+","no data","no data","no data","no data","+","+","+","no data","ENST00000352511.4","activin A receptor, type IIB ",21,3,1,1,1,1,0,0,1,2,"hsa-miR-101-3p.1",-0.21,-0.51,"> 0.99","2007, 2009, 2011\n"]
["mir-23b","miR-23-3p      ","ACVR2B","no data","no data","no data","+","no data","no data","no data","no data","+","+","+","no data","ENST00000352511.4","activin A receptor, type IIB ",21,2,0,1,1,0,0,0,0,3,"hsa-miR-23a-3p",-0.04,-0.14,0.33,"2007, 2009, 2011\n"]
["mir-29b","miR-29-3p ","ADAMTS2","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000251582.7","ADAM metallopeptidase with thrombospondin type 1 motif, 2 ",2767,4,1,3,0,1,0,0,1,2,"hsa-miR-29b-3p",-0.77,-0.77,"> 0.99",2011]
["mir-29b","miR-29-3p ","ADAMTS9","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000295903.4","ADAM metallopeptidase with thrombospondin type 1 motif, 9 ",5,2,1,0,1,0,0,0,0,0,"hsa-miR-29b-3p",-0.8,-0.8,"> 0.99","2005, 2007, 2009, 2011\n"]
["mir-30c","miR-30-5p   ","ADRA2A","no data","+","no data","no data","no data","no data","+","no data","no data","no data","no data","no data","ENST00000280155.2","adrenoceptor alpha 2A ",239,2,1,0,1,0,0,0,0,0,"hsa-miR-30c-5p",-0.41,-0.43,0.98,"2009, 2011\n"]
["miR-138","miR-138-5p","AGO1","no data","no data","+","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000373204.4","argonaute RISC catalytic component 1 ",402,2,1,1,0,1,0,0,1,0,"hsa-miR-138-5p",-0.5,-0.54,"> 0.99","2005, 2007, 2009, 2011\n"]
["mir-143","miR-143-3p ","AGO1","no data","no data","+","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000373204.4","argonaute RISC catalytic component 1 ",402,2,2,0,0,1,1,0,0,1,"hsa-miR-143-3p",-0.08,-0.1,0.36,"\n"]
["mir-148a","miR-148-3p/152-3p","AGO1","no data","no data","+","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000373204.4","argonaute RISC catalytic component 1 ",402,2,1,1,0,4,2,1,1,4,"hsa-miR-148a-3p",-0.35,-0.42,0.86,"2005, 2007, 2009, 2011\n"]
["mir-218","miR-218-5p","AGO1","no data","no data","+","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000373204.4","argonaute RISC catalytic component 1 ",402,2,0,0,2,0,0,0,0,1,"hsa-miR-218-5p",-0.08,-0.08,0.96,"2005, 2007, 2009, 2011\n"]
["mir-29b","miR-29-3p ","AGO1","no data","no data","+","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000373204.4","argonaute RISC catalytic component 1 ",402,4,0,3,1,0,0,0,0,0,"hsa-miR-29a-3p",-0.34,-0.4,"> 0.99","2005, 2007\n"]
["let-7a/let-7c","let-7-5p/98-5p","AGO3","no data","+","+","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000373191.4","argonaute RISC catalytic component 3 ",198,3,1,0,2,0,0,0,0,1,"hsa-let-7d-5p",-0.28,-0.38,"> 0.99","2005, 2007, 2009, 2011\n"]
["mir-23b","miR-23-3p      ","AGO3","no data","+","+","no data","no data","no data",null,"no data","+","no data","no data","no data","ENST00000373191.4","argonaute RISC catalytic component 3 ",198,2,0,1,1,3,2,0,1,1,"hsa-miR-23c",-0.05,-0.14,0.45,"\n"]
["mir-29b","miR-29-3p ","AGO3","no data","+","+","no data","no data","no data",null,"no data","+","no data","no data","no data","ENST00000373191.4","argonaute RISC catalytic component 3 ",198,2,1,1,0,0,0,0,0,1,"hsa-miR-29a-3p",-0.19,-0.49,0.99,"\n"]
["let-7a/let-7c","let-7-5p/98-5p","AGO4","no data","no data","+","no data","no data","no data","no data","no data","+","no data","+","+","ENST00000373210.3","argonaute RISC catalytic component 4 ",96,2,0,0,2,0,0,0,0,0,"hsa-let-7d-5p",-0.4,-0.49,0.97,"2005, 2007, 2009, 2011\n"]
["miR-138","miR-138-5p","AGO4","no data","no data","+","no data","no data","no data","no data","no data","+","no data","+","+","ENST00000373210.3","argonaute RISC catalytic component 4 ",96,2,0,0,2,1,0,1,0,0,"hsa-miR-138-5p",-0.37,-0.37,0.85,"2005, 2007, 2009, 2011\n"]
["miR-222","miR-221-3p/222-3p     ","AIDA","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000340020.6","axin interactor, dorsalization associated ",48,2,0,0,2,0,0,0,0,2,"hsa-miR-221-3p",-0.47,-0.47,0.75,"2009, 2011\n"]
["mir-23b","miR-23-3p      ","AMBRA1","no data","+","no data","no data","no data","no data","no data","no data","+","no data","+","+","ENST00000314845.3","autophagy/beclin-1 regulator 1 ",35,2,0,2,0,1,1,0,0,0,"hsa-miR-23c",-0.2,-0.2,0.39,"2005, 2007, 2009, 2011\n"]
["miR-125-5p","miR-125-5p","AMER2","no data","no data","+","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000357816.2","APC membrane recruitment protein 2 ",7,2,0,0,2,0,0,0,0,0,"hsa-miR-125a-5p",-0.21,-0.28,0.87,"2007, 2009, 2011\n"]
["mir-22","miR-22-3p   ","APBB2","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","ENST00000295974.8","amyloid beta (A4) precursor protein-binding, family B, member 2 ",704,2,0,0,2,1,0,1,0,1,"hsa-miR-22-3p",-0.51,-0.55,0.81,"2005, 2007, 2009, 2011\n"]
["miR-101","miR-101-3p.1  ","APP","+","+","+","no data","no data","no data","no data","+","no data","no data","+","+","ENST00000346798.3","amyloid beta (A4) precursor protein ",4570,2,1,0,1,0,0,0,0,3,"hsa-miR-101-3p.1",-0.54,-0.59,0.89,"2005, 2007, 2009, 2011\n"]
["miR-101","miR-101-3p.1  ","ARID1A","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000324856.7","AT rich interactive domain 1A (SWI-like) ",31,2,1,0,1,1,0,0,1,1,"hsa-miR-101-3p.1",-0.13,-0.2,0.83,"2005, 2007, 2009, 2011\n"]
["miR-101","miR-101-3p.1  ","ARID5B","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000279873.7","AT rich interactive domain 5B (MRF1-like) ",397,2,1,0,1,0,0,0,0,0,"hsa-miR-101-3p.1",-0.15,-0.15,0.74,"2007, 2009, 2011\n"]
["mir-26a","miR-26-5p  ","ARPP19","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000566423.1","cAMP-regulated phosphoprotein, 19kDa ",1316,2,1,0,1,2,0,1,1,0,"hsa-miR-26a-5p",-0.78,-1.03,0.99,"2005, 2007, 2009, 2011\n"]
["mir-22","miR-22-3p   ","ARRB1","no data","+","no data","no data","no data","no data","+","+","no data","no data","no data","+","ENST00000420843.2","arrestin, beta 1 ",598,2,1,1,0,1,0,1,0,0,"hsa-miR-22-3p",-0.65,-0.8,0.93,"2005, 2007, 2009, 2011\n"]
["miR-101","miR-101-3p.1  ","ASPN","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","ENST00000375543.1","asporin ",5,2,2,0,0,0,0,0,0,0,"hsa-miR-101-3p.1",-0.84,-0.84,0.48,"2005, 2007, 2009, 2011\n"]
["mir-23b","miR-23-3p      ","ASXL3","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000269197.5","additional sex combs like 3 (Drosophila) ",65,2,1,1,0,0,0,0,0,1,"hsa-miR-23c",-0.28,-0.28,0.53,"\n"]
["mir-29b","miR-29-3p ","ASXL3","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000269197.5","additional sex combs like 3 (Drosophila) ",65,2,0,2,0,1,0,1,0,0,"hsa-miR-29b-3p",-0.53,-0.53,0.95,"\n"]
["mir-148a","miR-148-3p/152-3p","ATP6AP2","no data","no data","+","no data","no data","no data","+","no data","no data","no data","+","no data","ENST00000378438.4","ATPase, H+ transporting, lysosomal accessory protein 2 ",6001,2,2,0,0,0,0,0,0,0,"hsa-miR-148a-3p",-1.26,-1.26,0.96,"2005, 2007, 2009, 2011\n"]
["mir-17","miR-17-5p/20-5p/93-5p/106-5p/519-3p","ATXN1L","no data","+","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000427980.2","ataxin 1-like ",12,2,1,1,0,0,0,0,0,1,"hsa-miR-519d-3p",-0.22,-0.22,0.99,2011]
["let-7a/let-7c","let-7-5p/98-5p","BACH1","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000286800.3","BTB and CNC homology 1, basic leucine zipper transcription factor 1 ",273,2,2,0,0,0,0,0,0,0,"hsa-let-7d-5p",-0.73,-0.75,"> 0.99","2005, 2007, 2009, 2011\n"]
["miR-125-5p","miR-125-5p","BAP1","+","+","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000460680.1","BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) ",445,2,1,1,0,1,0,1,0,0,"hsa-miR-125b-5p",-0.5,-0.53,0.72,2011]
["miR-101","miR-101-3p.1  ","BBX","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","+","no data","ENST00000415149.2","bobby sox homolog (Drosophila) ",141,2,1,0,1,4,0,1,3,2,"hsa-miR-101-3p.1",-0.18,-0.2,0.85,2011]
["mir-218","miR-218-5p","BBX","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","+","no data","ENST00000415149.2","bobby sox homolog (Drosophila) ",141,3,0,0,3,0,0,0,0,0,"hsa-miR-218-5p",-0.24,-0.26,0.97,2011]
["mir-26a","miR-26-5p  ","BBX","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","+","no data","ENST00000415149.2","bobby sox homolog (Drosophila) ",141,2,0,2,0,1,0,0,1,0,"hsa-miR-26a-5p",-0.15,-0.17,0.79,"2005, 2007, 2011\n"]
["mir-218","miR-218-5p","BCL11B","no data","+","no data","no data","no data","no data","no data","no data","+","no data","+","+","ENST00000357195.3","B-cell CLL/lymphoma 11B (zinc finger protein) ",73,2,1,0,1,0,0,0,0,0,"hsa-miR-218-5p",-0.08,-0.08,0.88,"2005, 2007, 2009, 2011\n"]
["miR-101","miR-101-3p.1  ","BCL2L11","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","+","ENST00000393256.3","BCL2-like 11 (apoptosis facilitator) ",105,2,1,0,1,0,0,0,0,1,"hsa-miR-101-3p.1",-0.25,-0.31,0.78,"2007, 2009, 2011\n"]
["mir-148a","miR-148-3p/152-3p","BCL2L11","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","+","ENST00000393256.3","BCL2-like 11 (apoptosis facilitator) ",105,2,1,0,1,1,0,1,0,0,"hsa-miR-148b-3p",-0.19,-0.73,0.98,"2007, 2009, 2011\n"]
["mir-17","miR-17-5p/20-5p/93-5p/106-5p/519-3p","BCL2L11","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","+","ENST00000393256.3","BCL2-like 11 (apoptosis facilitator) ",105,2,1,0,1,0,0,0,0,3,"hsa-miR-20b-5p",-0.17,-0.21,0.94,"2005, 2007, 2009, 2011\n"]
["miR-138","miR-138-5p","BCL9L","no data","no data","+","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000334801.3","B-cell CLL/lymphoma 9-like ",91,3,1,1,1,1,0,1,0,0,"hsa-miR-138-5p",-0.02,-0.54,"ORF","\n"]
["mir-22","miR-22-3p   ","BCL9L","no data","no data","+","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000334801.3","B-cell CLL/lymphoma 9-like ",91,2,0,2,0,1,1,0,0,1,"hsa-miR-22-3p",-0.34,-0.43,0.77,"2005, 2007, 2009, 2011\n"]
["mir-17","miR-17-5p/20-5p/93-5p/106-5p/519-3p","BHLHE41","no data","+","no data","no data","no data","no data","no data","+","+","no data","no data","no data","ENST00000242728.4","basic helix-loop-helix family, member e41 ",50,2,0,1,1,0,0,0,0,0,"hsa-miR-519d-3p",-0.26,-0.28,0.82,"2005, 2007, 2009, 2011\n"]
["mir-218","miR-218-5p","BICD1","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000548411.1","bicaudal D homolog 1 (Drosophila) ",205,2,1,1,0,2,0,1,1,0,"hsa-miR-218-5p",-0.27,-0.3,0.57,"2009, 2011\n"]
["mir-218","miR-218-5p","BMI1","+","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000376663.3","BMI1 polycomb ring finger oncogene ",200,2,2,0,0,0,0,0,0,0,"hsa-miR-218-5p",-0.61,-0.74,0.9,"2007, 2009, 2011\n"]
["mir-23b","miR-23-3p      ","BMP2K","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","ENST00000335016.5","BMP2 inducible kinase ",164,2,2,0,0,4,1,0,3,0,"hsa-miR-23a-3p",-0.18,-0.19,0.46,"\n"]
["mir-26a","miR-26-5p  ","BMP2K","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","ENST00000335016.5","BMP2 inducible kinase ",164,2,1,0,1,0,0,0,0,2,"hsa-miR-26a-5p",-0.29,-0.3,0.8,"\n"]
["mir-17","miR-17-5p/20-5p/93-5p/106-5p/519-3p","BMPR2","no data","+","no data","+","no data","+","no data","no data","+","+","+","no data","ENST00000374574.2","bone morphogenetic protein receptor, type II (serine/threonine kinase) ",287,2,0,2,0,2,0,2,0,4,"hsa-miR-519d-3p",-0.42,-0.56,0.93,"2005, 2007, 2009, 2011\n"]
["miR-21","miR-21-5p/590-5p  ","BMPR2","no data","+","no data","+","no data","+","no data","no data","+","+","+","no data","ENST00000374574.2","bone morphogenetic protein receptor, type II (serine/threonine kinase) ",287,2,1,1,0,1,0,1,0,4,"hsa-miR-21-5p",-0.12,-0.29,0.56,"2009, 2011\n"]
["mir-17","miR-17-5p/20-5p/93-5p/106-5p/519-3p","BNIP2","+","no data","no data","no data","no data","no data","+","no data","+","no data","+","+","ENST00000267859.3","BCL2/adenovirus E1B 19kDa interacting protein 2 ",1255,2,1,0,1,1,0,1,0,2,"hsa-miR-20b-5p",-0.28,-0.34,0.93,"2005, 2007, 2009, 2011\n"]
["mir-26a","miR-26-5p  ","BTBD7","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000334746.5","BTB (POZ) domain containing 7 ",590,2,1,0,1,0,0,0,0,0,"hsa-miR-26a-5p",-0.19,-0.23,0.94,"2005, 2007, 2009, 2011\n"]
["miR-125-5p","miR-125-5p","BTG2","+","+","no data","no data","no data","no data","no data","no data","+","no data","+","+","ENST00000290551.4","BTG family, member 2 ",758,2,0,2,0,0,0,0,0,0,"hsa-miR-125a-5p",-0.37,-0.37,0.56,"\n"]
["mir-29b","miR-29-3p ","BTG2","+","+","no data","no data","no data","no data","no data","no data","+","no data","+","+","ENST00000290551.4","BTG family, member 2 ",758,2,0,1,1,0,0,0,0,0,"hsa-miR-29a-3p",-0.41,-0.41,0.93,"2005, 2007, 2009, 2011\n"]
["miR-138","miR-138-5p","CADM1","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","+","+","ENST00000452722.3","cell adhesion molecule 1 ",676,2,0,0,2,0,0,0,0,0,"hsa-miR-138-5p",0,-0.3,0.95,2007]
["mir-29b","miR-29-3p ","CAMK2G","+","no data","no data","no data","no data","no data","+","no data","+","no data","+","no data","ENST00000351293.3","calcium/calmodulin-dependent protein kinase II gamma ",14,2,0,2,0,0,0,0,0,1,"hsa-miR-29b-3p",-0.35,-0.35,0.93,"2005, 2007, 2009, 2011\n"]
["miR-138","miR-138-5p","CAMK2N1","+","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000375078.3","calcium/calmodulin-dependent protein kinase II inhibitor 1 ",6631,2,0,1,1,0,0,0,0,0,"hsa-miR-138-5p",-0.7,-0.71,0.88,2007]
["mir-17","miR-17-5p/20-5p/93-5p/106-5p/519-3p","CAMK2N1","+","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000375078.3","calcium/calmodulin-dependent protein kinase II inhibitor 1 ",6631,2,0,2,0,1,0,1,0,0,"hsa-miR-519d-3p",-0.43,-0.69,0.93,"2007, 2009\n"]
["miR-125-5p","miR-125-5p","CAMK4","no data","no data","no data","no data","no data","no data","no data","no data","+","+","no data","no data","ENST00000282356.4","calcium/calmodulin-dependent protein kinase IV ",73,2,1,1,0,0,0,0,0,1,"hsa-miR-125b-5p",-0.12,-0.21,0.25,"\n"]
["mir-26a","miR-26-5p  ","CAMSAP1","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000389532.4","calmodulin regulated spectrin-associated protein 1 ",966,2,2,0,0,0,0,0,0,0,"hsa-miR-26a-5p",-0.14,-0.18,"> 0.99","2005, 2007, 2009, 2011\n"]
["miR-125-5p","miR-125-5p","CAMSAP3","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000446248.2","calmodulin regulated spectrin-associated protein family, member 3 ",14,2,0,1,1,0,0,0,0,0,"hsa-miR-125a-5p",-0.35,-0.35,0.64,"2007, 2009, 2011\n"]
["mir-26a","miR-26-5p  ","CASZ1","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000377022.3","castor zinc finger 1 ",5,3,1,0,2,0,0,0,0,0,"hsa-miR-26b-5p",-0.34,-0.34,"> 0.99","2007, 2009, 2011\n"]
["let-7a/let-7c","let-7-5p/98-5p","CBX5","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000209875.4","chromobox homolog 5 ",360,2,2,0,0,1,0,0,1,0,"hsa-let-7d-5p",-0.21,-0.96,"> 0.99",2011]
["mir-29b","miR-29-3p ","CBX5","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000209875.4","chromobox homolog 5 ",360,2,0,1,1,3,1,1,1,0,"hsa-miR-29b-3p",-0.27,-0.6,"> 0.99",2011]
["mir-218","miR-218-5p","CBX8","no data","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000269385.4","chromobox homolog 8 ",474,2,1,1,0,0,0,0,0,0,"hsa-miR-218-5p",-0.04,-0.32,0.97]
["mir-23b","miR-23-3p      ","CCDC71L","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000523505.1","coiled-coil domain containing 71-like ",410,2,2,0,0,1,0,0,1,2,"hsa-miR-23c",-0.09,-0.32,0.17,2011]
["let-7a/let-7c","let-7-5p/98-5p","CCND2","+","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","ENST00000261254.3","cyclin D2 ",66,3,0,0,3,0,0,0,0,1,"hsa-let-7d-5p",-0.58,-0.7,"> 0.99","2005, 2007, 2009, 2011\n"]
["miR-101","miR-101-3p.1  ","CCNT2","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000295238.6","cyclin T2 ",381,3,0,1,2,1,0,0,1,3,"hsa-miR-101-3p.1",-0.2,-0.39,0.88,"2007, 2011\n"]
["mir-23b","miR-23-3p      ","CCNT2","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000295238.6","cyclin T2 ",381,3,1,0,2,0,0,0,0,0,"hsa-miR-23c",-0.21,-0.21,0.65,"2005, 2007, 2009, 2011\n"]
["mir-30c","miR-30-5p   ","CCNT2","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000295238.6","cyclin T2 ",381,2,1,0,1,0,0,0,0,0,"hsa-miR-30c-5p",-0.41,-0.41,0.99,"2005, 2007, 2009, 2011\n"]
["let-7a/let-7c","let-7-5p/98-5p","CDC34","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","ENST00000215574.4","cell division cycle 34 ",1810,2,1,0,1,0,0,0,0,0,"hsa-let-7d-5p",-0.72,-0.92,"> 0.99","2005, 2007, 2009, 2011\n"]
["mir-29b","miR-29-3p ","CDC42","+","no data","+","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000344548.3","cell division cycle 42 ",34,2,1,1,0,0,0,0,0,0,"hsa-miR-29a-3p",-0.58,-0.58,0.69,"2005, 2007, 2009\n"]
["miR-125-5p","miR-125-5p","CDH5","no data","+","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000341529.3","cadherin 5, type 2 (vascular endothelium) ",8,2,1,0,1,0,0,0,0,0,"hsa-miR-125b-5p",-0.55,-0.55,0.96,"2009, 2011\n"]
["mir-148a","miR-148-3p/152-3p","CDK19","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","ENST00000368911.3","cyclin-dependent kinase 19 ",51,2,1,1,0,1,0,1,0,0,"hsa-miR-148a-3p",-0.49,-0.87,0.98,"2003, 2005, 2007, 2009, 2011\n"]
["mir-148a","miR-148-3p/152-3p","CDK5R1","+","+","no data","no data","no data","no data","no data","no data","+","no data","+","+","ENST00000313401.3","cyclin-dependent kinase 5, regulatory subunit 1 (p35) ",335,2,1,1,0,0,0,0,0,0,"hsa-miR-148a-3p",-0.73,-0.73,0.93,"2005, 2007, 2009, 2011\n"]
["mir-26a","miR-26-5p  ","CDK6","+","+","no data","no data","no data","no data","no data","+","+","+","+","no data","ENST00000265734.4","cyclin-dependent kinase 6 ",1116,2,2,0,0,2,0,0,2,2,"hsa-miR-26a-5p",-0.2,-0.23,0.96,"2005, 2007, 2009, 2011\n"]
["mir-29b","miR-29-3p ","CDK6","+","+","no data","no data","no data","no data","no data","+","+","+","+","no data","ENST00000265734.4","cyclin-dependent kinase 6 ",1116,2,0,1,1,1,0,1,0,0,"hsa-miR-29a-3p",-0.44,-0.49,0.99,"2007, 2009, 2011\n"]
["let-7a/let-7c","let-7-5p/98-5p","CDK8","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000536792.1","cyclin-dependent kinase 8 ",280,3,1,1,1,0,0,0,0,0,"hsa-miR-98-5p",-0.67,-0.67,"ORF"]
["miR-101","miR-101-3p.1  ","CDK8","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000536792.1","cyclin-dependent kinase 8 ",280,2,2,0,0,0,0,0,0,0,"hsa-miR-101-3p.1",-0.85,-0.87,0.92,"2009, 2011\n"]
["mir-26a","miR-26-5p  ","CDK8","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000536792.1","cyclin-dependent kinase 8 ",280,3,1,1,1,0,0,0,0,1,"hsa-miR-26a-5p",-0.56,-0.57,0.96,"2009, 2011\n"]
["mir-17","miR-17-5p/20-5p/93-5p/106-5p/519-3p","CDKN1A","+","+","no data","no data","no data","no data","no data","no data","no data","no data","+","+","ENST00000244741.5","cyclin-dependent kinase inhibitor 1A (p21, Cip1) ",1458,2,0,2,0,0,0,0,0,0,"hsa-miR-519d-3p",-0.45,-0.47,0.93,"2005, 2007, 2009, 2011\n"]
["miR-222","miR-221-3p/222-3p     ","CDKN1B","+","+","no data","no data","no data","no data","no data","+","+","no data","+","+","ENST00000228872.4","cyclin-dependent kinase inhibitor 1B (p27, Kip1) ",587,2,2,0,0,0,0,0,0,0,"hsa-miR-222-3p",-1.05,-1.05,0.9,"2005, 2007, 2009, 2011\n"]
["miR-101","miR-101-3p.1  ","CDYL","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000343762.5","chromodomain protein, Y-like ",24,2,2,0,0,0,0,0,0,0,"hsa-miR-101-3p.1",-0.79,-0.98,0.83,"2005, 2007, 2009, 2011\n"]
["mir-23b","miR-23-3p      ","CELF1","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000395290.2","CUGBP, Elav-like family member 1 ",153,3,1,2,0,1,0,1,0,1,"hsa-miR-23a-3p",-0.08,-0.12,0.66,2011]
["miR-125-5p","miR-125-5p","CEP85","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000252992.4","centrosomal protein 85kDa ",471,2,0,2,0,0,0,0,0,0,"hsa-miR-125a-5p",-0.39,-0.39,0.83,"2007, 2009, 2011\n"]
["mir-26a","miR-26-5p  ","CLASP2","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000539981.1","cytoplasmic linker associated protein 2 ",554,2,2,0,0,0,0,0,0,1,"hsa-miR-26b-5p",-0.12,-0.28,0.66,"2005, 2007, 2009, 2011\n"]
["mir-23b","miR-23-3p      ","CNOT2","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000229195.3","CCR4-NOT transcription complex, subunit 2 ",1189,2,0,1,1,3,1,1,1,0,"hsa-miR-23c",-0.07,-0.56,0.53,"2007, 2009, 2011\n"]
["miR-138","miR-138-5p","CNOT6L","+","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000504123.1","CCR4-NOT transcription complex, subunit 6-like ",23,2,1,1,0,0,0,0,0,1,"hsa-miR-138-5p",-0.11,-0.58,0.78,"2007, 2009, 2011\n"]
["mir-23b","miR-23-3p      ","CNOT6L","+","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000504123.1","CCR4-NOT transcription complex, subunit 6-like ",23,3,1,2,0,3,1,1,1,0,"hsa-miR-23a-3p",-0.29,-0.39,0.64,"2007, 2009, 2011\n"]
["mir-29b","miR-29-3p ","COL11A1","no data","no data","no data","no data","no data","no data","no data","no data","+","+","+","no data","ENST00000370096.3","collagen, type XI, alpha 1 ",160,2,0,2,0,0,0,0,0,0,"hsa-miR-29a-3p",-0.8,-0.8,0.97,"2005, 2007, 2009, 2011\n"]
["mir-29b","miR-29-3p ","COL19A1","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000322773.4","collagen, type XIX, alpha 1 ",5,2,1,1,0,0,0,0,0,1,"hsa-miR-29a-3p",-0.55,-0.55,"> 0.99","2005, 2007, 2009, 2011\n"]
["mir-29b","miR-29-3p ","COL1A1","no data","no data","+","no data","no data","no data","no data","no data","+","+","+","no data","ENST00000225964.5","collagen, type I, alpha 1 ",73360,3,1,0,2,0,0,0,0,0,"hsa-miR-29a-3p",-2.72,-2.76,"> 0.99",2011]
["mir-29b","miR-29-3p ","COL1A2","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000297268.6","collagen, type I, alpha 2 ",877,2,1,0,1,0,0,0,0,1,"hsa-miR-29a-3p",-0.91,-1.1,0.99,2011]
["let-7a/let-7c","let-7-5p/98-5p","COL27A1","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000356083.3","collagen, type XXVII, alpha 1 ",620,2,0,1,1,0,0,0,0,0,"hsa-let-7d-5p",-0.48,-0.48,"> 0.99"]
["mir-29b","miR-29-3p ","COL3A1","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000304636.3","collagen, type III, alpha 1 ",215,2,2,0,0,0,0,0,0,1,"hsa-miR-29b-3p",-1.06,-1.71,"> 0.99",2011]
["mir-29b","miR-29-3p ","COL4A3","no data","+","no data","no data","no data","no data","no data","no data","no data","no data","+","+","ENST00000396578.3","collagen, type IV, alpha 3 (Goodpasture antigen) ",286,2,1,1,0,0,0,0,0,0,"hsa-miR-29a-3p",-0.26,-0.26,0.96,2011]
["mir-29b","miR-29-3p ","COL5A1","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000371817.3","collagen, type V, alpha 1 ",3111,3,2,1,0,1,0,1,0,1,"hsa-miR-29a-3p",-0.44,-0.87,"> 0.99","2007, 2009, 2011\n"]
["mir-29b","miR-29-3p ","COL5A2","no data","no data","no data","no data","no data","no data","no data","no data","+","+","+","no data","ENST00000374866.3","collagen, type V, alpha 2 ",4327,2,1,0,1,0,0,0,0,0,"hsa-miR-29a-3p",-0.61,-0.94,"> 0.99","2005, 2007, 2009, 2011\n"]
["mir-29b","miR-29-3p ","COL5A3","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000264828.3","collagen, type V, alpha 3 ",5,3,1,2,0,0,0,0,0,1,"hsa-miR-29a-3p",-0.73,-0.73,"> 0.99","2003, 2005, 2007, 2009, 2011\n"]
["mir-29b","miR-29-3p ","COL9A1","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000357250.6","collagen, type IX, alpha 1 ",9,2,0,1,1,0,0,0,0,0,"hsa-miR-29a-3p",-0.59,-0.59,0.99,"2005, 2007\n"]
["miR-222","miR-221-3p/222-3p     ","CPEB3","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000412050.4","cytoplasmic polyadenylation element binding protein 3 ",48,2,1,1,0,0,0,0,0,0,"hsa-miR-222-3p",-0.42,-0.42,0.67,"2009, 2011\n"]
["miR-125-5p","miR-125-5p","CREB1","no data","+","no data","no data","no data","no data","no data","no data","+","+","+","+","ENST00000432329.2","cAMP responsive element binding protein 1 ",295,2,0,1,1,0,0,0,0,0,"hsa-miR-125a-5p",-0.09,-0.31,0.91,2011]
["mir-218","miR-218-5p","CREB1","no data","+","no data","no data","no data","no data","no data","no data","+","+","+","+","ENST00000432329.2","cAMP responsive element binding protein 1 ",295,3,2,0,1,0,0,0,0,1,"hsa-miR-218-5p",-0.15,-0.45,"> 0.99",2011]
["mir-26a","miR-26-5p  ","CREBBP","no data","no data","no data","no data","no data","no data","no data","+","+","no data","+","+","ENST00000262367.5","CREB binding protein ",532,2,0,0,2,0,0,0,0,0,"hsa-miR-26b-5p",-0.2,-0.35,0.92,"2005, 2007, 2009, 2011\n"]
["mir-143","miR-143-3p ","CRLF3","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000324238.6","cytokine receptor-like factor 3 ",5,2,1,1,0,0,0,0,0,0,"hsa-miR-143-3p",-0.27,-0.58,0.27,"2009, 2011\n"]
["mir-148a","miR-148-3p/152-3p","CSF1","no data","+","no data","no data","no data","no data","no data","no data","+","+","+","no data","ENST00000329608.6","colony stimulating factor 1 (macrophage) ",290,2,1,1,0,1,1,0,0,2,"hsa-miR-152-3p",-0.38,-0.38,0.72,"2005, 2007, 2009, 2011\n"]
["mir-23b","miR-23-3p      ","CSNK1G3","no data","no data","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000360683.2","casein kinase 1, gamma 3 ",28,2,2,0,0,1,0,0,1,0,"hsa-miR-23c",-0.15,-0.37,0.53,"2005, 2007, 2009, 2011\n"]
["mir-23b","miR-23-3p      ","CTCF","+","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000264010.4","CCCTC-binding factor (zinc finger protein) ",1037,2,1,1,0,0,0,0,0,0,"hsa-miR-23a-3p",-0.47,-0.47,0.62,"2005, 2007, 2009, 2011\n"]
["miR-125-5p","miR-125-5p","CTDSP2","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000398073.2","CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 ",991,2,0,0,2,0,0,0,0,0,"hsa-miR-125a-5p",-0.3,-0.32,0.82,"2009, 2011\n"]
["let-7a/let-7c","let-7-5p/98-5p","CTDSPL2","no data","no data","no data","+","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000260327.4","CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 ",457,2,1,0,1,0,0,0,0,1,"hsa-let-7d-5p",-0.37,-0.6,"> 0.99",2007]
["mir-218","miR-218-5p","CUL3","+","+","+","no data","no data","no data","+","no data","no data","no data","+","+","ENST00000264414.4","cullin 3 ",1476,2,0,1,1,0,0,0,0,1,"hsa-miR-218-5p",-0.06,-0.41,0.96,"2005, 2007, 2009, 2011\n"]
["let-7a/let-7c","let-7-5p/98-5p","DIAPH2","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000324765.8","diaphanous-related formin 2 ",91,2,0,2,0,0,0,0,0,1,"hsa-let-7g-5p",-0.5,-0.59,0.98,"2007, 2009\n"]
["let-7a/let-7c","let-7-5p/98-5p","DLC1","no data","+","no data","no data","no data","no data","no data","no data","no data","no data","+","+","ENST00000276297.4","deleted in liver cancer 1 ",970,2,0,0,2,0,0,0,0,0,"hsa-let-7d-5p",-0.25,-0.36,"> 0.99","2005, 2007, 2009, 2011\n"]
["mir-29b","miR-29-3p ","DLG2","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","no data","no data","ENST00000398309.2","discs, large homolog 2 (Drosophila) ",15,2,2,0,0,0,0,0,0,0,"hsa-miR-29a-3p",-0.24,-0.24,0.98,"2007, 2009, 2011\n"]
["miR-101","miR-101-3p.1  ","DNMT3A","+","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000380746.4","DNA (cytosine-5-)-methyltransferase 3 alpha ",221,2,0,1,1,0,0,0,0,2,"hsa-miR-101-3p.1",-0.29,-0.3,0.99,"2005, 2007, 2009, 2011\n"]
["mir-143","miR-143-3p ","DNMT3A","+","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000380746.4","DNA (cytosine-5-)-methyltransferase 3 alpha ",221,2,0,2,0,0,0,0,0,0,"hsa-miR-143-3p",-0.09,-0.1,0.43,"2005, 2007\n"]
["mir-218","miR-218-5p","DNMT3A","+","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000380746.4","DNA (cytosine-5-)-methyltransferase 3 alpha ",221,2,0,1,1,0,0,0,0,0,"hsa-miR-218-5p",-0.1,-0.12,0.84,"2005, 2007\n"]
["mir-26a","miR-26-5p  ","DNMT3A","+","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000380746.4","DNA (cytosine-5-)-methyltransferase 3 alpha ",221,2,1,0,1,0,0,0,0,1,"hsa-miR-26a-5p",-0.04,-0.3,0.99,"\n"]
["mir-29b","miR-29-3p ","DNMT3A","+","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000380746.4","DNA (cytosine-5-)-methyltransferase 3 alpha ",221,3,0,2,1,2,0,2,0,10,"hsa-miR-29b-3p",-0.2,-0.96,"> 0.99","2005, 2007, 2009, 2011\n"]
["mir-29b","miR-29-3p ","DOT1L","+","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000398665.3","DOT1-like histone H3K79 methyltransferase ",439,4,0,3,1,2,0,2,0,2,"hsa-miR-29b-3p",-0.33,-0.39,0.52,"2009, 2011\n"]
["let-7a/let-7c","let-7-5p/98-5p","DTX2","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","no data","ENST00000413936.2","deltex homolog 2 (Drosophila) ",76,2,1,0,1,0,0,0,0,0,"hsa-let-7d-5p",-0.82,-0.82,"> 0.99","2005, 2007, 2009, 2011\n"]
["let-7a/let-7c","let-7-5p/98-5p","DTX4","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","no data","ENST00000227451.3","deltex homolog 4 (Drosophila) ",5,2,1,0,1,0,0,0,0,1,"hsa-let-7d-5p",-0.29,-0.29,0.93,"2009, 2011\n"]
["miR-138","miR-138-5p","DTX4","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","no data","ENST00000227451.3","deltex homolog 4 (Drosophila) ",5,2,2,0,0,0,0,0,0,1,"hsa-miR-138-5p",-0.55,-0.55,0.87,"2009, 2011\n"]
["mir-29b","miR-29-3p ","DTX4","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","no data","ENST00000227451.3","deltex homolog 4 (Drosophila) ",5,2,0,2,0,1,0,1,0,0,"hsa-miR-29a-3p",-0.26,-0.26,0.9,"2009, 2011\n"]
["let-7a/let-7c","let-7-5p/98-5p","DUSP16","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","no data","no data","ENST00000298573.4","dual specificity phosphatase 16 ",444,2,1,0,1,1,0,1,0,0,"hsa-let-7d-5p",-0.67,-0.68,0.94,"2005, 2007, 2009, 2011\n"]
["miR-125-5p","miR-125-5p","DUSP3","+","no data","no data","no data","no data","no data","+","no data","no data","no data","no data","no data","ENST00000226004.3","dual specificity phosphatase 3 ",836,2,0,1,1,0,0,0,0,1,"hsa-miR-125a-5p",-0.25,-0.53,0.97,2011]
["miR-125-5p","miR-125-5p","DVL3","no data","no data","+","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000313143.3","dishevelled segment polarity protein 3 ",373,2,0,2,0,0,0,0,0,0,"hsa-miR-125b-5p",0,-0.17,0.94,"2005, 2007, 2009, 2011\n"]
["mir-17","miR-17-5p/20-5p/93-5p/106-5p/519-3p","E2F1","+","+","no data","no data","no data","no data","no data","no data","+","no data","+","+","ENST00000343380.5","E2F transcription factor 1 ",479,2,0,2,0,0,0,0,0,0,"hsa-miR-20a-5p",-0.46,-0.48,0.93,"2005, 2007, 2009, 2011\n"]
["mir-26a","miR-26-5p  ","E2F7","+","+","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000416496.2","E2F transcription factor 7 ",308,2,1,0,1,0,0,0,0,1,"hsa-miR-26b-5p",-0.36,-0.37,0.98,"2005, 2007, 2009, 2011\n"]
["miR-101","miR-101-3p.1  ","EBF1","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000313708.6","early B-cell factor 1 ",42,2,0,0,2,0,0,0,0,1,"hsa-miR-101-3p.1",-0.11,-0.12,0.56,2011]
["mir-218","miR-218-5p","EBF3","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000368648.3","early B-cell factor 3 ",101,2,1,1,0,0,0,0,0,0,"hsa-miR-218-5p",-0.32,-0.39,0.95,"2007, 2009, 2011\n"]
["mir-23b","miR-23-3p      ","EGR3","no data","+","no data","no data","no data","no data","no data","no data","+","no data","+","+","ENST00000519492.1","early growth response 3 ",21,2,0,1,1,0,0,0,0,1,"hsa-miR-23c",-0.24,-0.32,0.36,"2005, 2007, 2009, 2011\n"]
["miR-138","miR-138-5p","EIF4EBP1","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000338825.4","eukaryotic translation initiation factor 4E binding protein 1 ",121,2,1,1,0,1,0,1,0,3,"hsa-miR-138-5p",-1.06,-1.31,"> 0.99","2009, 2011\n"]
["mir-26a","miR-26-5p  ","EIF4G2","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","+","ENST00000526148.1","eukaryotic translation initiation factor 4 gamma, 2 ",61971,2,0,2,0,0,0,0,0,0,"hsa-miR-26b-5p",-0.43,-0.43,0.75,"2005, 2007, 2009, 2011\n"]
["mir-23b","miR-23-3p      ","ELF2","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000394235.2","E74-like factor 2 (ets domain transcription factor) ",26,2,1,0,1,0,0,0,0,0,"hsa-miR-23c",-0.3,-0.3,0.72,"2005, 2007, 2009, 2011\n"]
["mir-23b","miR-23-3p      ","ELF4","no data","+","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000335997.7","E74-like factor 4 (ets domain transcription factor) ",69,2,1,0,1,0,0,0,0,0,"hsa-miR-23a-3p",-0.24,-0.24,0.65,2011]
["mir-148a","miR-148-3p/152-3p","ELF5","no data","+","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000257832.2","E74-like factor 5 (ets domain transcription factor) ",5,2,1,0,1,0,0,0,0,0,"hsa-miR-152-3p",-0.61,-0.61,0.86,"2005, 2007, 2009, 2011\n"]
["mir-29b","miR-29-3p ","ELN","no data","+","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000252034.7","elastin ",445,3,2,1,0,0,0,0,0,0,"hsa-miR-29b-3p",-0.97,-0.97,"> 0.99","2007, 2009, 2011\n"]
["mir-17","miR-17-5p/20-5p/93-5p/106-5p/519-3p","EPHA4","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000281821.2","EPH receptor A4 ",64,2,1,1,0,0,0,0,0,0,"hsa-miR-93-5p",-0.54,-0.56,0.98,"2005, 2007, 2009, 2011\n"]
["mir-17","miR-17-5p/20-5p/93-5p/106-5p/519-3p","EPHA7","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","+","ENST00000369303.4","EPH receptor A7 ",213,2,1,1,0,0,0,0,0,0,"hsa-miR-20a-5p",-0.34,-0.41,0.95,"2005, 2007, 2009, 2011\n"]
["miR-138","miR-138-5p","EPHA8","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","+","no data","ENST00000166244.3","EPH receptor A8 ",5,2,2,0,0,0,0,0,0,0,"hsa-miR-138-5p",-0.46,-0.46,0.99,"2003, 2005, 2007, 2009, 2011\n"]
["mir-26a","miR-26-5p  ","EPS15","no data","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000371730.2","epidermal growth factor receptor pathway substrate 15 ",325,2,1,0,1,0,0,0,0,0,"hsa-miR-26a-5p",-0.26,-0.29,0.62,"2005, 2007, 2009, 2011\n"]
["mir-23b","miR-23-3p      ","EXT1","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","+","no data","ENST00000378204.2","exostosin glycosyltransferase 1 ",694,2,2,0,0,1,0,0,1,3,"hsa-miR-23c",0,-0.1,0.25,"\n"]
["miR-101","miR-101-3p.1  ","EYA1","no data","+","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000388742.4","eyes absent homolog 1 (Drosophila) ",222,2,1,1,0,1,0,0,1,0,"hsa-miR-101-3p.1",-0.81,-0.86,0.73,"2005, 2007, 2011\n"]
["miR-101","miR-101-3p.1  ","EZH2","+","+","no data","no data","no data","no data","+","no data","+","no data","+","no data","ENST00000478654.1","enhancer of zeste homolog 2 (Drosophila) ",577,2,1,1,0,0,0,0,0,0,"hsa-miR-101-3p.1",-0.91,-0.91,0.91,2011]
["miR-101","miR-101-3p.1  ","FAT3","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000298047.6","FAT atypical cadherin 3 ",30,2,2,0,0,2,0,1,1,3,"hsa-miR-101-3p.1",-0.07,-0.11,0.9,"2009, 2011\n"]
["mir-29b","miR-29-3p ","FBN1","no data","no data","no data","+","no data","no data","no data","no data","+","+","+","no data","ENST00000316623.5","fibrillin 1 ",798,2,1,1,0,0,0,0,0,1,"hsa-miR-29a-3p",-0.58,-0.61,"> 0.99","2005, 2007, 2009, 2011\n"]
["miR-101","miR-101-3p.1  ","FBN2","no data","no data","no data","no data","no data","no data","no data","no data","+","+","+","no data","ENST00000262464.4","fibrillin 2 ",167,2,1,0,1,2,1,0,1,0,"hsa-miR-101-3p.1",-0.14,-0.15,0.86,"2005, 2007, 2009, 2011\n"]
["mir-218","miR-218-5p","FBN2","no data","no data","no data","no data","no data","no data","no data","no data","+","+","+","no data","ENST00000262464.4","fibrillin 2 ",167,2,1,1,0,1,0,0,1,1,"hsa-miR-218-5p",-0.11,-0.12,0.41,"2005, 2007\n"]
["let-7a/let-7c","let-7-5p/98-5p","FIGN","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000333129.3","fidgetin ",10,6,3,0,3,0,0,0,0,0,"hsa-let-7d-5p",-1.46,-2.11,"> 0.99","2007, 2009, 2011\n"]
["miR-101","miR-101-3p.1  ","FIGN","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000333129.3","fidgetin ",10,2,0,1,1,0,0,0,0,1,"hsa-miR-101-3p.1",-0.18,-0.36,0.73,"\n"]
["mir-23b","miR-23-3p      ","FIGN","+","no data","no data","no data","no data","no data",null,"no data","no data","no data","no data",null,"ENST00000333129.3","fidgetin ",10,2,1,0,1,0,0,0,0,2,"hsa-miR-23a-3p",-0.08,-0.17,0.59]
["miR-101","miR-101-3p.1  ","FLRT3","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000378053.3","fibronectin leucine rich transmembrane protein 3 ",11,2,2,0,0,0,0,0,0,2,"hsa-miR-101-3p.1",-0.86,-0.86,0.96,"2005, 2007, 2009, 2011\n"]
["mir-22","miR-22-3p   ","FMNL3","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000335154.5","formin-like 3 ",132,2,0,2,0,1,0,1,0,2,"hsa-miR-22-3p",-0.06,-0.22,0.25,"\n"]
["mir-218","miR-218-5p","FOXN3","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000345097.4","forkhead box N3 ",42,2,1,1,0,0,0,0,0,3,"hsa-miR-218-5p",-0.03,-0.23,0.69,"2009, 2011\n"]
["let-7a/let-7c","let-7-5p/98-5p","FOXP2","no data","+","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000408937.3","forkhead box P2 ",169,3,0,2,1,0,0,0,0,1,"hsa-let-7g-5p",-0.65,-0.92,"> 0.99",2011]
["miR-21","miR-21-5p/590-5p  ","FOXP2","no data","+","no data","no data","no data","no data",null,"no data","no data","+","no data",null,"ENST00000408937.3","forkhead box P2 ",169,2,0,1,1,1,0,1,0,1,"hsa-miR-21-5p",-0.04,-0.09,0.39,2011]
["mir-29b","miR-29-3p ","FREM2","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000280481.7","FRAS1 related extracellular matrix protein 2 ",33,2,0,1,1,1,0,1,0,0,"hsa-miR-29a-3p",-0.33,-0.35,0.99,"2009, 2011\n"]
["miR-222","miR-221-3p/222-3p     ","FRK","no data","+","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000606080.1","fyn-related kinase ",37,2,0,0,2,2,1,0,1,1,"hsa-miR-222-3p",-0.31,-0.51,0.76,"\n"]
["miR-138","miR-138-5p","FSD1","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000597590.1","fibronectin type III and SPRY domain containing 1 ",81,2,0,1,1,0,0,0,0,0,"hsa-miR-138-5p",-0.46,-0.46,"ORF","\n"]
["mir-17","miR-17-5p/20-5p/93-5p/106-5p/519-3p","FURIN","no data","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000268171.3","furin (paired basic amino acid cleaving enzyme) ",2306,2,0,1,1,0,0,0,0,1,"hsa-miR-20b-5p",-0.25,-0.25,0.78,"2005, 2007, 2009, 2011\n"]
["mir-23b","miR-23-3p      ","FUT9","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000302103.5","fucosyltransferase 9 (alpha (1,3) fucosyltransferase) ",5,2,2,0,0,6,0,4,2,2,"hsa-miR-23a-3p",-0.4,-0.4,0.67,"2007, 2009, 2011\n"]
["let-7a/let-7c","let-7-5p/98-5p","FZD3","+","+","+","no data","no data","no data","no data","no data","+","no data","+","+","ENST00000240093.3","frizzled family receptor 3 ",192,2,2,0,0,1,0,0,1,0,"hsa-let-7d-5p",-0.9,-1,"> 0.99",2011]
["miR-101","miR-101-3p.1  ","FZD4","no data","no data","+","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000531380.1","frizzled family receptor 4 ",5,2,2,0,0,0,0,0,0,2,"hsa-miR-101-3p.1",-0.74,-0.74,0.89,"2005, 2007, 2009, 2011\n"]
["mir-31/31-5p","miR-31-5p","FZD4","no data","no data","+","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000531380.1","frizzled family receptor 4 ",5,2,1,1,0,0,0,0,0,1,"hsa-miR-31-5p",-0.36,-0.36,0.41,"2009, 2011\n"]
["mir-22","miR-22-3p   ","FZD8","no data","no data","+","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000374694.1","frizzled family receptor 8 ",791,2,2,0,0,0,0,0,0,0,"hsa-miR-22-3p",0,-0.41,0.97,"\n"]
["mir-17","miR-17-5p/20-5p/93-5p/106-5p/519-3p","G3BP1","no data","no data","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000394123.3","GTPase activating protein (SH3 domain) binding protein 1 ",688,2,2,0,0,1,0,1,0,7,"hsa-miR-519d-3p",-0.04,-0.16,0.95]
["miR-101","miR-101-3p.1  ","GAB1","no data","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000262995.4","GRB2-associated binding protein 1 ",26,3,0,2,1,0,0,0,0,3,"hsa-miR-101-3p.1",-0.33,-0.45,"> 0.99",2011]
["mir-31/31-5p","miR-31-5p","GCNT4","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000322348.4","glucosaminyl (N-acetyl) transferase 4, core 2 ",19,2,0,1,1,1,0,1,0,1,"hsa-miR-31-5p",-0.44,-0.55,0.61,"\n"]
["mir-483","miR-483-3p.1","GDF11","no data","+","no data","no data","no data","+","+","no data","+","no data","+","+","ENST00000257868.5","growth differentiation factor 11 ",847,2,1,1,0,0,0,0,0,1,"hsa-miR-483-3p.1",-0.13,-0.39,"N/A","\n"]
["miR-125-5p","miR-125-5p","GJC1","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000426548.1","gap junction protein, gamma 1, 45kDa ",195,3,0,2,1,0,0,0,0,0,"hsa-miR-125b-5p",-0.49,-0.57,"> 0.99","2009, 2011\n"]
["mir-26a","miR-26-5p  ","GMNC","+","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000442080.1","geminin coiled-coil domain containing ",19,2,0,1,1,0,0,0,0,0,"hsa-miR-26a-5p",-0.35,-0.35,0.71,2011]
["mir-26a","miR-26-5p  ","GNA13","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","+","+","ENST00000439174.2","guanine nucleotide binding protein (G protein), alpha 13 ",190,2,2,0,0,0,0,0,0,0,"hsa-miR-26a-5p",-0.16,-0.22,0.96,2011]
["miR-125-5p","miR-125-5p","GPC4","no data","no data","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000370828.3","glypican 4 ",542,2,1,1,0,0,0,0,0,0,"hsa-miR-125a-5p",-0.35,-0.48,0.97,"2005, 2007, 2009, 2011\n"]
["miR-222","miR-221-3p/222-3p     ","GPM6A","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000280187.7","glycoprotein M6A ",335,2,0,1,1,0,0,0,0,0,"hsa-miR-222-3p",-0.39,-0.4,0.53,"2005, 2007, 2009, 2011\n"]
["miR-125-5p","miR-125-5p","GRB10","no data","no data","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000398812.2","growth factor receptor-bound protein 10 ",1382,2,0,1,1,0,0,0,0,0,"hsa-miR-125a-5p",-0.4,-0.51,0.93,"2005, 2007, 2009, 2011\n"]
["mir-26a","miR-26-5p  ","GREB1L","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000580732.2","growth regulation by estrogen in breast cancer-like ",30,2,2,0,0,0,0,0,0,0,"hsa-miR-26a-5p",-0.08,-0.08,0.3,"\n"]
["mir-218","miR-218-5p","GREM1","no data","+","+","+","no data","+","no data","no data","+","+","+","+","ENST00000560677.1","gremlin 1, DAN family BMP antagonist ",752,2,0,2,0,1,0,0,1,0,"hsa-miR-218-5p",-0.53,-0.67,0.83,"2009, 2011\n"]
["miR-101","miR-101-3p.1  ","GRIN2A","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","+","no data","ENST00000562109.1","glutamate receptor, ionotropic, N-methyl D-aspartate 2A ",5,2,0,2,0,3,0,3,0,2,"hsa-miR-101-3p.1",-0.02,-0.28,0.72,"\n"]
["let-7a/let-7c","let-7-5p/98-5p","GRIN2B","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","+","no data","ENST00000609686.1","glutamate receptor, ionotropic, N-methyl D-aspartate 2B ",5,2,0,0,2,1,0,0,1,3,"hsa-let-7d-5p",-0.43,-0.43,"> 0.99","\n"]
["mir-26a","miR-26-5p  ","GSK3B","no data","no data","+","no data","no data","no data","no data","no data","+","no data","+","+","ENST00000264235.8","glycogen synthase kinase 3 beta ",498,2,1,1,0,1,0,1,0,2,"hsa-miR-26a-5p",-0.15,-0.22,0.92,"2005, 2007, 2011\n"]
["mir-218","miR-218-5p","HAPLN1","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000274341.4","hyaluronan and proteoglycan link protein 1 ",5,2,1,1,0,0,0,0,0,0,"hsa-miR-218-5p",-0.47,-0.47,0.97,"2005, 2007, 2009, 2011\n"]
["mir-29b","miR-29-3p ","HBP1","+","no data","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000222574.4","HMG-box transcription factor 1 ",167,2,2,0,0,0,0,0,0,0,"hsa-miR-29b-3p",-0.84,-0.84,0.95,"2005, 2007, 2009, 2011\n"]
["mir-29b","miR-29-3p ","HECW1","no data","no data","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000395891.2","HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 ",11,2,0,2,0,0,0,0,0,0,"hsa-miR-29a-3p",-0.16,-0.39,0.98,"2005, 2007\n"]
["miR-138","miR-138-5p","HIF1AN","no data","no data","no data","no data","no data","no data","no data","+","+","no data","+","no data","ENST00000299163.6","hypoxia inducible factor 1, alpha subunit inhibitor ",1545,2,1,1,0,0,0,0,0,3,"hsa-miR-138-5p",-0.27,-0.51,0.68,"2009, 2011\n"]
["let-7a/let-7c","let-7-5p/98-5p","HIF3A","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","+","ENST00000377670.4","hypoxia inducible factor 3, alpha subunit ",5,2,1,0,1,0,0,0,0,0,"hsa-miR-98-5p",-0.3,-0.3,"> 0.99","2009, 2011\n"]
["mir-29b","miR-29-3p ","HIF3A","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","+","ENST00000377670.4","hypoxia inducible factor 3, alpha subunit ",5,2,2,0,0,0,0,0,0,1,"hsa-miR-29a-3p",-0.61,-0.61,"> 0.99","2005, 2007, 2009, 2011\n"]
["miR-222","miR-221-3p/222-3p     ","HIPK2","+","+","no data","+","no data","+","no data","no data","+","no data","+","+","ENST00000406875.3","homeodomain interacting protein kinase 2 ",48,2,1,1,0,0,0,0,0,0,"hsa-miR-222-3p",-0.08,-0.08,0.71,"2009, 2011\n"]
["miR-101","miR-101-3p.1  ","HIVEP3","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000372583.1","human immunodeficiency virus type I enhancer binding protein 3 ",84,2,1,1,0,0,0,0,0,0,"hsa-miR-101-3p.1",-0.31,-0.31,"> 0.99","\n"]
["let-7a/let-7c","let-7-5p/98-5p","HMGA2","+","+","no data","no data","no data","no data","no data","no data","+","no data","+","+","ENST00000403681.2","high mobility group AT-hook 2 ",8021,7,1,3,3,0,0,0,0,1,"hsa-let-7d-5p",-2.67,-2.69,"> 0.99","2005, 2007, 2009, 2011\n"]
["mir-26a","miR-26-5p  ","HMGA2","+","+","no data","no data","no data","no data",null,"+","no data","+","+",null,"ENST00000403681.2","high mobility group AT-hook 2 ",8021,3,0,1,2,0,0,0,0,0,"hsa-miR-26a-5p",-0.63,-0.64,0.89,"2005, 2007, 2009, 2011\n"]
["let-7a/let-7c","let-7-5p/98-5p","HOXA1","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000355633.5","homeobox A1 ",157,2,1,1,0,0,0,0,0,0,"hsa-let-7f-5p",-0.53,-0.53,"ORF","\n"]
["mir-23b","miR-23-3p      ","HOXD10","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000249501.4","homeobox D10 ",182,2,0,2,0,0,0,0,0,0,"hsa-miR-23a-3p",-0.22,-0.22,0.41,2011]
["miR-101","miR-101-3p.1  ","HTRA3","no data","no data","no data","+","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000307358.2","HtrA serine peptidase 3 ",5161,2,1,0,1,0,0,0,0,0,"hsa-miR-101-3p.1",-0.57,-0.57,0.89,"2007, 2009, 2011\n"]
["mir-218","miR-218-5p","ICK","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000350082.5","intestinal cell (MAK-like) kinase ",18,2,1,1,0,1,0,1,0,0,"hsa-miR-218-5p",-0.2,-0.56,0.85,"2005, 2007, 2009, 2011\n"]
["miR-101","miR-101-3p.1  ","ID4","+","+","no data","no data","no data","no data","no data","no data","+","+","+","no data","ENST00000378700.3","inhibitor of DNA binding 4, dominant negative helix-loop-helix protein ",3400,2,0,1,1,0,0,0,0,1,"hsa-miR-101-3p.1",-0.2,-0.46,0.69,"2007, 2009, 2011\n"]
["mir-29b","miR-29-3p ","IGF1","+","+","no data","no data","no data","no data","+","no data","+","+","+","+","ENST00000337514.6","insulin-like growth factor 1 (somatomedin C) ",19,2,2,0,0,0,0,0,0,0,"hsa-miR-29a-3p",-0.16,-0.73,"> 0.99","2005, 2007, 2009, 2011\n"]
["let-7a/let-7c","let-7-5p/98-5p","IGF2BP1","no data","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000290341.3","insulin-like growth factor 2 mRNA binding protein 1 ",460,5,3,1,1,0,0,0,0,1,"hsa-let-7d-5p",-0.98,-1.51,"> 0.99","2007, 2009, 2011\n"]
["mir-218","miR-218-5p","IKZF1","+","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000331340.3","IKAROS family zinc finger 1 (Ikaros) ",11,2,1,1,0,1,0,0,1,1,"hsa-miR-218-5p",-0.24,-0.32,0.66,"2007, 2009, 2011\n"]
["mir-23b","miR-23-3p      ","IKZF3","no data","+","no data","no data","no data","no data","no data","no data","+","no data","+","+","ENST00000346872.3","IKAROS family zinc finger 3 (Aiolos) ",7,2,1,1,0,1,0,0,1,2,"hsa-miR-23a-3p",-0.02,-0.06,0.29,"\n"]
["miR-138","miR-138-5p","ILDR2","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000469934.2","immunoglobulin-like domain containing receptor 2 ",7,2,0,2,0,0,0,0,0,0,"hsa-miR-138-5p",-0.1,-0.35,0.6,2011]
["mir-148a","miR-148-3p/152-3p","INO80","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000361937.3","INO80 complex subunit ",279,2,1,1,0,0,0,0,0,0,"hsa-miR-148a-3p",-0.67,-0.67,0.99,"2007, 2009, 2011\n"]
["mir-29b","miR-29-3p ","IRS1","no data","+","no data","no data","no data","no data","+","no data","no data","no data","no data","no data","ENST00000305123.5","insulin receptor substrate 1 ",804,2,0,1,1,0,0,0,0,2,"hsa-miR-29b-3p",-0.04,-0.15,0.97,2011]
["mir-31/31-5p","miR-31-5p","ISL1","no data","+","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000230658.7","ISL LIM homeobox 1 ",67,2,0,0,2,0,0,0,0,0,"hsa-miR-31-5p",-0.45,-0.45,0.42,"2007, 2009, 2011\n"]
["mir-218","miR-218-5p","ISLR2","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000361742.3","immunoglobulin superfamily containing leucine-rich repeat 2 ",5,2,0,1,1,0,0,0,0,0,"hsa-miR-218-5p",-0.12,-0.12,0.88,"2009, 2011\n"]
["mir-148a","miR-148-3p/152-3p","ITGA5","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000293379.4","integrin, alpha 5 (fibronectin receptor, alpha polypeptide) ",5599,2,1,1,0,0,0,0,0,0,"hsa-miR-148a-3p",-0.37,-0.37,0.83,"2005, 2007, 2009, 2011\n"]
["miR-101","miR-101-3p.1  ","ITGA8","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000378076.3","integrin, alpha 8 ",7,2,0,1,1,0,0,0,0,1,"hsa-miR-101-3p.1",-0.15,-0.15,0.98,"\n"]
["let-7a/let-7c","let-7-5p/98-5p","ITGB3","no data","+","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000559488.1","integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) ",176,2,0,1,1,0,0,0,0,2,"hsa-let-7d-5p",-0.46,-0.46,"> 0.99","2005, 2007, 2009, 2011\n"]
["mir-26a","miR-26-5p  ","ITGB8","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000222573.4","integrin, beta 8 ",17,2,1,0,1,1,0,0,1,1,"hsa-miR-26b-5p",-0.19,-0.25,0.96,"2007, 2009, 2011\n"]
["mir-26a","miR-26-5p  ","JAG1","no data","+","no data","no data","no data","no data","no data","+","+","+","+","no data","ENST00000254958.5","jagged 1 ",421,2,1,0,1,0,0,0,0,0,"hsa-miR-26b-5p",-0.35,-0.36,0.94,"2005, 2007, 2009, 2011\n"]
["mir-26a","miR-26-5p  ","JARID2","no data","+","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000341776.2","jumonji, AT rich interactive domain 2 ",199,2,0,1,1,0,0,0,0,0,"hsa-miR-26b-5p",-0.25,-0.25,0.83,"2009, 2011\n"]
["mir-218","miR-218-5p","JMY","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","ENST00000396137.4","junction mediating and regulatory protein, p53 cofactor ",10,2,1,1,0,1,0,1,0,1,"hsa-miR-218-5p",-0.62,-0.79,0.86,"2009, 2011\n"]
["miR-138","miR-138-5p","KDM5A","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000399788.2","lysine (K)-specific demethylase 5A ",118,2,0,0,2,2,1,1,0,0,"hsa-miR-138-5p",-0.42,-0.51,0.99,"2007, 2009, 2011\n"]
["mir-29b","miR-29-3p ","KDM5B","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000367265.3","lysine (K)-specific demethylase 5B ",187,2,0,1,1,0,0,0,0,0,"hsa-miR-29b-3p",-0.32,-0.47,"> 0.99","2005, 2007, 2009, 2011\n"]
["mir-29b","miR-29-3p ","KIAA1024","no data","+","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000305428.3","KIAA1024 ",5,3,0,3,0,0,0,0,0,0,"hsa-miR-29a-3p",-0.53,-0.53,"> 0.99","2005, 2007, 2009, 2011\n"]
["mir-29b","miR-29-3p ","KIAA2022","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000055682.6","KIAA2022 ",5,2,2,0,0,2,0,0,2,0,"hsa-miR-29b-3p",-0.47,-0.47,"> 0.99","2007, 2009, 2011\n"]
["miR-101","miR-101-3p.1  ","KIF2A","+","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000381103.2","kinesin heavy chain member 2A ",905,2,0,1,1,3,0,1,2,1,"hsa-miR-101-3p.1",-0.26,-0.43,0.68,2007]
["mir-218","miR-218-5p","KIF2A","+","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000381103.2","kinesin heavy chain member 2A ",905,2,1,1,0,0,0,0,0,0,"hsa-miR-218-5p",-0.28,-0.53,0.94,"2009, 2011\n"]
["mir-23b","miR-23-3p      ","KLF3","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000261438.5","Kruppel-like factor 3 (basic) ",515,4,1,1,2,0,0,0,0,1,"hsa-miR-23a-3p",-0.4,-0.67,0.84,"2005, 2007, 2009, 2011\n"]
["mir-26a","miR-26-5p  ","KLHL42","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000381271.2","kelch-like family member 42 ",2120,2,2,0,0,1,0,1,0,1,"hsa-miR-26a-5p",-0.61,-0.63,0.98,"2005, 2007, 2009, 2011\n"]
["mir-143","miR-143-3p ","KRAS","no data","+","no data","no data","no data","no data","+","no data","+","no data","+","+","ENST00000256078.4","Kirsten rat sarcoma viral oncogene homolog ",40,2,2,0,0,1,0,0,1,3,"hsa-miR-143-3p",-0.31,-0.62,0.84,"2005, 2007, 2009, 2011\n"]
["mir-23b","miR-23-3p      ","KSR1","no data","+","no data","no data","no data","no data","+","no data","no data","no data","no data","no data","ENST00000398988.3","kinase suppressor of ras 1 ",256,2,1,1,0,0,0,0,0,1,"hsa-miR-23a-3p",-0.09,-0.09,0.69,"\n"]
["mir-26a","miR-26-5p  ","LARP1","no data","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000336314.4","La ribonucleoprotein domain family, member 1 ",4979,2,1,0,1,1,0,0,1,0,"hsa-miR-26b-5p",-0.37,-0.37,0.99,"2007, 2009, 2011\n"]
["mir-218","miR-218-5p","LDLRAD4","no data","no data","no data","no data","no data","+","no data","no data","+","no data","no data","no data","ENST00000399848.3","low density lipoprotein receptor class A domain containing 4 ",314,2,1,0,1,0,0,0,0,0,"hsa-miR-218-5p",-0.14,-0.42,"> 0.99","2005, 2007, 2009, 2011\n"]
["mir-26a","miR-26-5p  ","LEF1","no data","+","+","+","no data","no data","no data","no data","+","+","+","+","ENST00000265165.1","lymphoid enhancer-binding factor 1 ",104,3,1,0,2,1,0,0,1,1,"hsa-miR-26a-5p",-0.4,-0.61,0.95,"2005, 2007, 2009, 2011\n"]
["miR-125-5p","miR-125-5p","LHX9","no data","+","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000367390.3","LIM homeobox 9 ",40,2,0,1,1,0,0,0,0,0,"hsa-miR-125a-5p",-0.37,-0.39,0.79,"\n"]
["mir-29b","miR-29-3p ","LOX","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000231004.4","lysyl oxidase ",3441,3,0,3,0,0,0,0,0,0,"hsa-miR-29b-3p",-0.25,-0.8,"> 0.99",2011]
["mir-26a","miR-26-5p  ","LOXL2","no data","+","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000389131.3","lysyl oxidase-like 2 ",701,2,1,0,1,0,0,0,0,0,"hsa-miR-26a-5p",-0.58,-0.59,0.93,"2009, 2011\n"]
["mir-29b","miR-29-3p ","LOXL2","no data","+","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000389131.3","lysyl oxidase-like 2 ",701,2,0,1,1,0,0,0,0,0,"hsa-miR-29a-3p",-0.57,-0.58,0.96,"2009, 2011\n"]
["mir-29b","miR-29-3p ","LRP6","+","+","+","no data","no data","no data","no data","no data","+","no data","+","+","ENST00000261349.4","low density lipoprotein receptor-related protein 6 ",157,2,0,2,0,1,0,1,0,0,"hsa-miR-29b-3p",-0.21,-0.31,0.98,"2009, 2011\n"]
["mir-29b","miR-29-3p ","LSM11","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000286307.5","LSM11, U7 small nuclear RNA associated ",1458,2,1,0,1,1,1,0,0,0,"hsa-miR-29a-3p",-0.49,-0.52,0.99,"2005, 2007, 2009, 2011\n"]
["mir-26a","miR-26-5p  ","MAB21L1","no data","+","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000379919.4","mab-21-like 1 (C. elegans) ",25,2,1,0,1,1,0,0,1,0,"hsa-miR-26a-5p",-0.71,-0.81,0.96,"2005, 2007, 2009, 2011\n"]
["mir-218","miR-218-5p","MAFG",null,"+","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000357736.4","v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G ",5,2,1,1,0,0,0,0,0,0,"hsa-miR-218-5p",-0.38,-0.38,0.97,"2005, 2007, 2009, 2011\n"]
["miR-101","miR-101-3p.1  ","MAGI2","+","+","no data","no data","no data","+","no data","no data","no data","no data","+","no data","ENST00000419488.1","membrane associated guanylate kinase, WW and PDZ domain containing 2 ",43,2,1,0,1,1,0,0,1,0,"hsa-miR-101-3p.1",-0.09,-0.1,0.52,"2007, 2009, 2011\n"]
["mir-23b","miR-23-3p      ","MAML2","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","no data","ENST00000524717.1","mastermind-like 2 (Drosophila) ",104,2,1,0,1,0,0,0,0,2,"hsa-miR-23b-3p",-0.29,-0.36,0.74,"\n"]
["mir-26a","miR-26-5p  ","MAP1B","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000296755.7","microtubule-associated protein 1B ",259,2,0,1,1,1,0,1,0,0,"hsa-miR-26a-5p",-0.11,-0.11,0.8,"2005, 2007, 2009, 2011\n"]
["miR-101","miR-101-3p.1  ","MAP3K4","no data","no data","no data","no data","no data","no data","+","no data","+","no data","+","no data","ENST00000366919.2","mitogen-activated protein kinase kinase kinase 4 ",241,2,0,0,2,0,0,0,0,0,"hsa-miR-101-3p.1",-0.11,-0.11,0.55,"2007, 2009, 2011\n"]
["mir-26a","miR-26-5p  ","MAP3K9","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","no data","+","ENST00000554752.2","mitogen-activated protein kinase kinase kinase 9 ",44,2,0,0,2,1,0,0,1,3,"hsa-miR-26a-5p",-0.22,-0.27,0.87,2011]
["mir-23b","miR-23-3p      ","MAP4K4","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","+","+","ENST00000413150.2","mitogen-activated protein kinase kinase kinase kinase 4 ",1551,2,1,1,0,0,0,0,0,0,"hsa-miR-23b-3p",-0.14,-0.36,0.66,"2005, 2007, 2009, 2011\n"]
["mir-29b","miR-29-3p ","MAP4K4","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","+","+","ENST00000413150.2","mitogen-activated protein kinase kinase kinase kinase 4 ",1551,2,0,1,1,0,0,0,0,0,"hsa-miR-29a-3p",-0.21,-0.37,0.98,"2005, 2007, 2009, 2011\n"]
["miR-101","miR-101-3p.1  ","MAPK1","+","+","no data","no data","no data","no data","+","no data","+","+","+","+","ENST00000215832.6","mitogen-activated protein kinase 1 ",630,2,0,1,1,3,0,2,1,3,"hsa-miR-101-3p.1",-0.28,-0.51,"> 0.99","2009, 2011\n"]
["miR-101","miR-101-3p.1  ","MAPK6","+","no data","no data","no data","no data","no data","+","no data","no data","no data","no data","no data","ENST00000261845.5","mitogen-activated protein kinase 6 ",24,2,0,0,2,0,0,0,0,2,"hsa-miR-101-3p.1",-0.22,-0.23,0.66,"2007, 2011\n"]
["miR-101","miR-101-3p.1  ","MARK1","no data","no data","+","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000366918.4","MAP/microtubule affinity-regulating kinase 1 ",192,2,0,1,1,1,0,0,1,1,"hsa-miR-101-3p.1",-0.17,-0.4,0.81,"2005, 2007, 2009, 2011\n"]
["let-7a/let-7c","let-7-5p/98-5p","MBD2","no data","+","+","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000256429.3","methyl-CpG binding domain protein 2 ",823,2,1,1,0,1,0,1,0,1,"hsa-let-7d-5p",-0.01,-0.73,0.99,2011]
["mir-218","miR-218-5p","MBD5","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000407073.1","methyl-CpG binding domain protein 5 ",7,2,1,0,1,0,0,0,0,2,"hsa-miR-218-5p",-0.04,-0.16,0.78]
["miR-222","miR-221-3p/222-3p     ","MBD5","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000407073.1","methyl-CpG binding domain protein 5 ",7,2,2,0,0,2,0,0,2,1,"hsa-miR-222-3p",-0.08,-0.5,0.58]
["miR-101","miR-101-3p.1  ","MBNL1","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000357472.3","muscleblind-like splicing regulator 1 ",135,2,1,0,1,1,0,0,1,0,"hsa-miR-101-3p.1",-0.45,-0.45,0.88,"2005, 2007, 2009, 2011\n"]
["mir-218","miR-218-5p","MBNL1","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000357472.3","muscleblind-like splicing regulator 1 ",135,2,0,1,1,0,0,0,0,2,"hsa-miR-218-5p",-0.44,-0.44,0.88,"2005, 2007, 2009, 2011\n"]
["mir-23b","miR-23-3p      ","MBTD1","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000586178.1","mbt domain containing 1 ",113,2,0,0,2,2,0,1,1,0,"hsa-miR-23c",-0.14,-0.14,0.5,2011]
["miR-138","miR-138-5p","MBTPS2","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","ENST00000379484.5","membrane-bound transcription factor peptidase, site 2 ",1711,2,0,1,1,1,1,0,0,0,"hsa-miR-138-5p",-0.58,-0.59,0.68,2011]
["mir-23b","miR-23-3p      ","MDFIC","no data","no data","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000393486.1","MyoD family inhibitor domain containing ",601,2,1,0,1,0,0,0,0,2,"hsa-miR-23a-3p",-0.41,-0.49,0.73,"2005, 2007, 2009, 2011\n"]
["mir-218","miR-218-5p","MDGA1","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000297153.7","MAM domain containing glycosylphosphatidylinositol anchor 1 ",240,2,2,0,0,1,0,0,1,3,"hsa-miR-218-5p",-0.62,-0.62,"> 0.99","2005, 2007, 2009, 2011\n"]
["mir-146b-5p","mir-146b-5p","MED1","+","+","no data","no data","no data","no data","no data","no data","+","no data","+","+","ENST00000300651.6","mediator complex subunit 1 ",87,2,1,1,0,0,0,0,0,1,"hsa-miR-146a-5p",-0.12,-0.13,"< 0.1","2009, 2011\n"]
["let-7a/let-7c","let-7-5p/98-5p","MEF2C","no data","+","no data","no data","no data","no data","+","no data","+","+","+","+","ENST00000340208.5","myocyte enhancer factor 2C ",70,2,0,0,2,0,0,0,0,0,"hsa-let-7d-5p",-0.03,-0.38,0.96,2011]
["miR-21","miR-21-5p/590-5p  ","MEF2C","no data","+","no data","no data","no data","no data","+","no data","+","+","+","+","ENST00000340208.5","myocyte enhancer factor 2C ",70,2,0,2,0,1,0,0,1,0,"hsa-miR-21-5p",-0.1,-0.15,0.76,2011]
["mir-23b","miR-23-3p      ","MEF2C","no data","+","no data","no data","no data","no data","+","no data","+","+","+","+","ENST00000340208.5","myocyte enhancer factor 2C ",70,2,2,0,0,0,0,0,0,1,"hsa-miR-23a-3p",-0.19,-0.25,"< 0.1","2005, 2007, 2009, 2011\n"]
["miR-101","miR-101-3p.1  ","MEF2D","no data","+","no data","no data","no data","no data","no data","no data","+","+","+","+","ENST00000464356.2","myocyte enhancer factor 2D ",759,2,1,0,1,0,0,0,0,0,"hsa-miR-101-3p.1",-0.25,-0.28,0.78,"2007, 2009, 2011\n"]
["miR-101","miR-101-3p.1  ","MEIS2","+","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000397624.3","Meis homeobox 2 ",63,2,0,0,2,1,0,0,1,0,"hsa-miR-101-3p.1",-0.2,-0.22,0.67,"2007, 2009, 2011\n"]
["mir-148a","miR-148-3p/152-3p","MEOX2","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000262041.5","mesenchyme homeobox 2 ",5,2,2,0,0,0,0,0,0,0,"hsa-miR-148a-3p",-0.97,-0.97,0.96,"2003, 2005, 2007, 2009, 2011\n"]
["mir-29b","miR-29-3p ","MGA","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000219905.7","MGA, MAX dimerization protein ",250,2,0,2,0,0,0,0,0,3,"hsa-miR-29a-3p",-0.19,-0.25,0.98,"2007, 2009, 2011\n"]
["let-7a/let-7c","let-7-5p/98-5p","MIB1","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","+","no data","ENST00000261537.6","mindbomb E3 ubiquitin protein ligase 1 ",897,2,0,2,0,0,0,0,0,1,"hsa-let-7f-5p",-0.45,-0.46,"> 0.99",2011]
["miR-101","miR-101-3p.1  ","MITF","no data","+","+","no data","no data","no data","no data","no data","+","+","+","+","ENST00000328528.6","microphthalmia-associated transcription factor ",593,2,1,0,1,0,0,0,0,2,"hsa-miR-101-3p.1",-0.35,-0.37,0.87,2011]
["mir-148a","miR-148-3p/152-3p","MITF","no data","+","+","no data","no data","no data","no data","no data","+","+","+","+","ENST00000328528.6","microphthalmia-associated transcription factor ",593,2,0,1,1,2,0,0,2,1,"hsa-miR-148a-3p",-0.74,-0.91,0.98,2011]
["mir-143","miR-143-3p ","MKL2","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000318282.5","MKL/myocardin-like 2 ",992,2,0,0,2,0,0,0,0,1,"hsa-miR-143-3p",-0.34,-0.34,0.45,"2009, 2011\n"]
["mir-17","miR-17-5p/20-5p/93-5p/106-5p/519-3p","MKL2","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000318282.5","MKL/myocardin-like 2 ",992,2,0,1,1,2,0,1,1,3,"hsa-miR-519d-3p",-0.25,-0.25,0.83,"2009, 2011\n"]
["mir-29b","miR-29-3p ","MMP16","no data","+","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","ENST00000286614.6","matrix metallopeptidase 16 (membrane-inserted) ",12,3,1,2,0,0,0,0,0,0,"hsa-miR-29a-3p",-0.32,-0.69,"> 0.99","\n"]
["mir-31/31-5p","miR-31-5p","MMP16","no data","+","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","ENST00000286614.6","matrix metallopeptidase 16 (membrane-inserted) ",12,2,2,0,0,3,0,1,2,2,"hsa-miR-31-5p",-0.45,-0.68,0.74,2007]
["mir-218","miR-218-5p","MOSPD1","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000370783.3","motile sperm domain containing 1 ",83,3,2,1,0,0,0,0,0,0,"hsa-miR-218-5p",-0.71,-1.17,0.93,"2005, 2007, 2009, 2011\n"]
["mir-143","miR-143-3p ","MSI2","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000284073.2","musashi RNA-binding protein 2 ",283,3,1,0,2,0,0,0,0,0,"hsa-miR-143-3p",-0.64,-0.64,0.84,2011]
["mir-218","miR-218-5p","MSI2","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000284073.2","musashi RNA-binding protein 2 ",283,2,0,1,1,1,0,1,0,1,"hsa-miR-218-5p",-0.21,-0.35,0.92,"\n"]
["mir-23b","miR-23-3p      ","MTSS1","no data","+","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000378017.3","metastasis suppressor 1 ",10,2,1,1,0,0,0,0,0,1,"hsa-miR-23c",-0.1,-0.21,0.37,"2005, 2007, 2009, 2011\n"]
["mir-148a","miR-148-3p/152-3p","MXD1","no data","+","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000264444.2","MAX dimerization protein 1 ",183,2,1,1,0,1,0,1,0,2,"hsa-miR-148a-3p",-0.65,-0.91,0.94,"2009, 2011\n"]
["mir-29b","miR-29-3p ","MXD1","no data","+","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000264444.2","MAX dimerization protein 1 ",183,2,0,2,0,0,0,0,0,2,"hsa-miR-29b-3p",-0.16,-0.7,0.98,"2009, 2011\n"]
["mir-17","miR-17-5p/20-5p/93-5p/106-5p/519-3p","MYT1L","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000399161.2","myelin transcription factor 1-like ",5,3,1,2,0,2,0,0,2,1,"hsa-miR-519d-3p",-0.51,-0.51,"> 0.99","2005, 2007, 2009, 2011\n"]
["mir-218","miR-218-5p","NACC1","no data","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000292431.4","nucleus accumbens associated 1, BEN and BTB (POZ) domain containing ",337,2,2,0,0,0,0,0,0,0,"hsa-miR-218-5p",-0.34,-0.37,"> 0.99","2005, 2007, 2009, 2011\n"]
["miR-101","miR-101-3p.1  ","NACC2","+","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","ENST00000371753.1","NACC family member 2, BEN and BTB (POZ) domain containing ",172,2,1,0,1,0,0,0,0,4,"hsa-miR-101-3p.1",-0.26,-0.37,0.9,2011]
["mir-23b","miR-23-3p      ","NACC2","+","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","ENST00000371753.1","NACC family member 2, BEN and BTB (POZ) domain containing ",172,3,1,2,0,0,0,0,0,1,"hsa-miR-23b-3p",-0.45,-0.51,0.83,"2005, 2007, 2009, 2011\n"]
["mir-26a","miR-26-5p  ","NACC2","+","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","ENST00000371753.1","NACC family member 2, BEN and BTB (POZ) domain containing ",172,2,1,0,1,1,0,0,1,1,"hsa-miR-26a-5p",-0.09,-0.13,0.97,2011]
["let-7a/let-7c","let-7-5p/98-5p","NAP1L1","no data","+","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000261182.8","nucleosome assembly protein 1-like 1 ",9072,2,1,0,1,1,0,1,0,1,"hsa-let-7b-5p",-0.02,-1.01,0.99,"2005, 2007, 2009, 2011\n"]
["mir-29b","miR-29-3p ","NASP","+","+","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000350030.3","nuclear autoantigenic sperm protein (histone-binding) ",8,2,1,1,0,0,0,0,0,0,"hsa-miR-29a-3p",-0.71,-0.71,0.88,"2003, 2005, 2007, 2009, 2011\n"]
["mir-29b","miR-29-3p ","NAV1","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000295624.6","neuron navigator 1 ",702,4,1,3,0,0,0,0,0,1,"hsa-miR-29b-3p",-0.54,-0.55,"> 0.99","2005, 2007, 2009, 2011\n"]
["mir-29b","miR-29-3p ","NAV3","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000228327.6","neuron navigator 3 ",277,3,1,1,1,0,0,0,0,1,"hsa-miR-29a-3p",-0.5,-0.5,"> 0.99","2003, 2005, 2007, 2009, 2011\n"]
["mir-17","miR-17-5p/20-5p/93-5p/106-5p/519-3p","NCOA3","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000341724.6","nuclear receptor coactivator 3 ",282,2,1,1,0,0,0,0,0,3,"hsa-miR-20b-5p",-0.22,-0.3,0.99,"2005, 2007, 2009, 2011\n"]
["mir-23b","miR-23-3p      ","NEDD4L","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000256832.7","neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase ",617,3,0,3,0,0,0,0,0,1,"hsa-miR-23c",-0.04,-0.14,0.56,"2009, 2011\n"]
["miR-125-5p","miR-125-5p","NEK10","+","no data","no data","no data","no data","no data","+","no data","no data","no data","no data","no data","ENST00000295720.6","NIMA-related kinase 10 ",66,2,2,0,0,0,0,0,0,0,"hsa-miR-125a-5p",-0.03,-0.88,"< 0.1","\n"]
["mir-23b","miR-23-3p      ","NEK6","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","ENST00000373603.1","NIMA-related kinase 6 ",3449,2,2,0,0,0,0,0,0,0,"hsa-miR-23b-3p",-0.47,-0.77,0.87,"2003, 2005, 2007, 2009, 2011\n"]
["mir-143","miR-143-3p ","NFATC1","no data","no data","+","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000253506.5","nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 ",74,2,2,0,0,0,0,0,0,0,"hsa-miR-143-3p",-0.27,-0.27,0.81,"2009, 2011\n"]
["miR-101","miR-101-3p.1  ","NFIB","no data","+","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000397575.3","nuclear factor I/B ",1149,2,0,1,1,1,0,1,0,4,"hsa-miR-101-3p.1",-0.32,-0.35,0.93,"2007, 2009, 2011\n"]
["miR-138","miR-138-5p","NFIB","no data","+","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000397575.3","nuclear factor I/B ",1149,3,0,0,3,1,0,1,0,3,"hsa-miR-138-5p",-0.68,-0.73,0.98,"2005, 2007, 2009, 2011\n"]
["mir-23b","miR-23-3p      ","NFIB","no data","+","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000397575.3","nuclear factor I/B ",1149,3,0,2,1,1,0,1,0,1,"hsa-miR-23c",-0.14,-0.17,0.54,"2007, 2009, 2011\n"]
["mir-29b","miR-29-3p ","NFIC","no data","+","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000346156.5","nuclear factor I/C (CCAAT-binding transcription factor) ",26,2,0,2,0,0,0,0,0,0,"hsa-miR-29a-3p",-0.18,-0.23,0.98,"\n"]
["mir-26a","miR-26-5p  ","NHS","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000380060.3","Nance-Horan syndrome (congenital cataracts and dental anomalies) ",72,2,2,0,0,1,0,0,1,1,"hsa-miR-26b-5p",-0.26,-0.26,0.97,"2005, 2007, 2009, 2011\n"]
["miR-138","miR-138-5p","NINJ1","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000375446.4","ninjurin 1 ",1216,2,1,1,0,2,1,1,0,3,"hsa-miR-138-5p",-0.77,-1.15,0.79,2011]
["mir-23b","miR-23-3p      ","NKAP","no data","+","no data","no data","no data","no data","no data","+","+","no data","no data","no data","ENST00000371410.3","NFKB activating protein ",422,2,1,1,0,0,0,0,0,1,"hsa-miR-23a-3p",-0.07,-0.13,0.37]
["mir-26a","miR-26-5p  ","NLK","no data","no data","+","no data","no data","no data","+","no data","no data","no data","no data","no data","ENST00000407008.3","nemo-like kinase ",61,3,0,0,3,0,0,0,0,1,"hsa-miR-26a-5p",-0.05,-0.42,0.94,"2005, 2007, 2009, 2011\n"]
["mir-31/31-5p","miR-31-5p","NR5A2","no data","+","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000367362.3","nuclear receptor subfamily 5, group A, member 2 ",121,2,1,1,0,1,0,0,1,0,"hsa-miR-31-5p",-0.68,-0.77,0.72,"2007, 2009, 2011\n"]
["let-7a/let-7c","let-7-5p/98-5p","NR6A1","no data","+","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000487099.2","nuclear receptor subfamily 6, group A, member 1 ",1082,4,2,2,0,1,0,1,0,0,"hsa-let-7i-5p",-1.24,-1.26,"> 0.99","\n"]
["mir-23b","miR-23-3p      ","NR6A1","no data","+","no data","no data","no data","no data","no data","+","no data","no data","no data","no data","ENST00000487099.2","nuclear receptor subfamily 6, group A, member 1 ",1082,3,2,1,0,0,0,0,0,0,"hsa-miR-23c",-0.43,-0.44,0.91,"2005, 2007, 2009, 2011\n"]
["let-7a/let-7c","let-7-5p/98-5p","NRAS","no data","+","no data","no data","no data","no data","+","no data","no data","no data","no data","no data","ENST00000369535.4","neuroblastoma RAS viral (v-ras) oncogene homolog ",551,2,0,1,1,0,0,0,0,0,"hsa-let-7f-5p",-0.52,-0.7,"> 0.99",2011]
["mir-23b","miR-23-3p      ","NRK","no data","+","no data","no data","no data","no data","+","no data","no data","no data","+","no data","ENST00000243300.9","Nik related kinase ",5,2,0,2,0,0,0,0,0,0,"hsa-miR-23c",-0.04,-0.04,0.44,"2005, 2007, 2009, 2011\n"]
["mir-26a","miR-26-5p  ","NUS1","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000368494.3","nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) ",302,2,0,1,1,3,1,0,2,2,"hsa-miR-26b-5p",-0.55,-0.55,0.82,"2007, 2009, 2011\n"]
["let-7a/let-7c","let-7-5p/98-5p","ONECUT1","no data","no data","no data","no data","no data","no data","no data","+","+","no data","+","no data","ENST00000560699.2","one cut homeobox 1 ",10,3,1,0,2,0,0,0,0,0,"hsa-let-7d-5p",-0.38,-0.96,"> 0.99"]
["let-7a/let-7c","let-7-5p/98-5p","ONECUT2","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000491143.2","one cut homeobox 2 ",847,3,1,0,2,3,0,1,2,1,"hsa-let-7d-5p",-0.53,-0.61,"> 0.99","2007, 2009, 2011\n"]
["mir-218","miR-218-5p","ONECUT2","no data","no data","no data","no data","no data","no data",null,"+","no data","+","no data",null,"ENST00000491143.2","one cut homeobox 2 ",847,4,2,1,1,1,0,1,0,1,"hsa-miR-218-5p",-0.79,-0.8,"> 0.99","2003, 2007, 2009, 2011\n"]
["let-7a/let-7c","let-7-5p/98-5p","ONECUT3","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000382349.4","one cut homeobox 3 ",5,2,1,0,1,0,0,0,0,0,"hsa-let-7d-5p",-0.38,-0.38,"> 0.99","\n"]
["mir-218","miR-218-5p","ONECUT3","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000382349.4","one cut homeobox 3 ",5,2,0,1,1,1,0,1,0,1,"hsa-miR-218-5p",-0.25,-0.25,0.97,"\n"]
["mir-23b","miR-23-3p      ","OSBPL8","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000393249.2","oxysterol binding protein-like 8 ",141,2,1,0,1,2,0,1,1,0,"hsa-miR-23a-3p",-0.01,-0.15,0.66,"2005, 2007, 2009, 2011\n"]
["mir-218","miR-218-5p","PAK3","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","+","no data","ENST00000372007.5","p21 protein (Cdc42/Rac)-activated kinase 3 ",8,2,0,2,0,0,0,0,0,1,"hsa-miR-218-5p",-0.21,-0.21,0.97,"\n"]
["mir-26a","miR-26-5p  ","PAX5","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000358127.4","paired box 5 ",5,2,1,0,1,0,0,0,0,2,"hsa-miR-26a-5p",-0.23,-0.23,0.89,"\n"]
["let-7a/let-7c","let-7-5p/98-5p","PBX1","+","+","no data","no data","no data","no data","no data","+","+","+","+","no data","ENST00000367897.1","pre-B-cell leukemia homeobox 1 ",18,2,0,1,1,0,0,0,0,1,"hsa-let-7g-5p",-0.49,-0.7,"> 0.99",2011]
["let-7a/let-7c","let-7-5p/98-5p","PBX2","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000375050.4","pre-B-cell leukemia homeobox 2 ",98,2,0,1,1,0,0,0,0,0,"hsa-let-7d-5p",-0.54,-0.54,"> 0.99",2011]
["let-7a/let-7c","let-7-5p/98-5p","PBX3","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000342287.5","pre-B-cell leukemia homeobox 3 ",1142,2,0,1,1,0,0,0,0,1,"hsa-let-7b-5p",-0.67,-0.71,"> 0.99","2005, 2007, 2009, 2011\n"]
["miR-101","miR-101-3p.1  ","PBX3","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000342287.5","pre-B-cell leukemia homeobox 3 ",1142,2,1,0,1,0,0,0,0,0,"hsa-miR-101-3p.1",-0.46,-0.48,0.8,"2007, 2009, 2011\n"]
["mir-26a","miR-26-5p  ","PDCD10","no data","+","no data","no data","no data","no data","+","+","no data","no data","+","+","ENST00000392750.2","programmed cell death 10 ",638,2,1,0,1,0,0,0,0,0,"hsa-miR-26b-5p",-0.27,-0.76,0.76,"2005, 2007, 2009, 2011\n"]
["mir-148a","miR-148-3p/152-3p","PDE4D","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000340635.6","phosphodiesterase 4D, cAMP-specific ",747,2,1,1,0,0,0,0,0,1,"hsa-miR-148a-3p",-0.35,-0.38,0.87,"2009, 2011\n"]
["miR-101","miR-101-3p.1  ","PDS5B","+","+","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000315596.10","PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae) ",1493,2,1,0,1,1,0,0,1,1,"hsa-miR-101-3p.1",-0.14,-0.37,0.42,"2007, 2009, 2011\n"]
["miR-138","miR-138-5p","PER2","+","+","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000254658.3","period circadian clock 2 ",106,3,0,1,2,2,0,1,1,2,"hsa-miR-138-5p",-0.5,-0.5,"< 0.1"]
["mir-31/31-5p","miR-31-5p","PEX5","no data","+","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000266563.5","peroxisomal biogenesis factor 5 ",2114,2,1,1,0,0,0,0,0,0,"hsa-miR-31-5p",-0.61,-0.61,0.62,"2007, 2009, 2011\n"]
["miR-125-5p","miR-125-5p","PHF15","no data","no data","no data","no data","no data","+","no data","no data","no data","no data","+","no data","ENST00000402835.1","PHD finger protein 15 ",387,2,1,1,0,0,0,0,0,0,"hsa-miR-125b-5p",-0.23,-0.35,0.98,"2005, 2007, 2009, 2011\n"]
["mir-29b","miR-29-3p ","PI15","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000260113.2","peptidase inhibitor 15 ",12,5,3,2,0,0,0,0,0,1,"hsa-miR-29b-3p",-1.5,-1.5,"> 0.99","2005, 2007, 2009, 2011\n"]
["miR-21","miR-21-5p/590-5p  ","PIK3R1","no data","no data","no data","no data","no data","no data","no data","no data","+","+","no data","+","ENST00000521381.1","phosphoinositide-3-kinase, regulatory subunit 1 (alpha) ",217,2,0,2,0,0,0,0,0,2,"hsa-miR-21-5p",-0.23,-0.24,0.77,"2007, 2009, 2011\n"]
["mir-17","miR-17-5p/20-5p/93-5p/106-5p/519-3p","PKD2","+","+","+","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000237596.2","polycystic kidney disease 2 (autosomal dominant) ",915,2,2,0,0,1,0,1,0,0,"hsa-miR-17-5p",-0.69,-0.69,"> 0.99","2005, 2007, 2009, 2011\n"]
["mir-17","miR-17-5p/20-5p/93-5p/106-5p/519-3p","PKNOX1","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000291547.5","PBX/knotted 1 homeobox 1 ",297,2,0,2,0,0,0,0,0,0,"hsa-miR-519d-3p",-0.15,-0.35,0.74,"2005, 2007, 2009, 2011\n"]
["mir-218","miR-218-5p","PLCG1","no data","+","no data","no data","no data","no data","no data","no data","no data","no data","+","+","ENST00000244007.3","phospholipase C, gamma 1 ",69,2,0,1,1,3,0,2,1,2,"hsa-miR-218-5p",-0.43,-0.56,0.97,"2005, 2007, 2009, 2011\n"]
["miR-125-5p","miR-125-5p","PLXNA1","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000393409.2","plexin A1 ",189,2,1,1,0,1,0,1,0,0,"hsa-miR-125a-5p",-0.11,-0.12,0.83,"2005, 2007, 2009, 2011\n"]
["miR-125-5p","miR-125-5p","PODXL","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000541194.1","podocalyxin-like ",2928,2,1,1,0,1,0,1,0,0,"hsa-miR-125b-5p",-0.48,-0.49,0.99,"2005, 2007, 2009, 2011\n"]
["mir-26a","miR-26-5p  ","POLR3G","no data","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000504930.1","polymerase (RNA) III (DNA directed) polypeptide G (32kD) ",67,3,2,0,1,1,0,0,1,1,"hsa-miR-26b-5p",-1.02,-1.02,0.97,"2009, 2011\n"]
["mir-143","miR-143-3p ","PPAP2B","no data","no data","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000371250.3","phosphatidic acid phosphatase type 2B ",81,2,1,1,0,1,1,0,0,2,"hsa-miR-143-3p",0,-0.16,0.28,"\n"]
["mir-23b","miR-23-3p      ","PPARGC1A","no data","+","no data","no data","no data","no data","no data","no data","+","no data","+","+","ENST00000264867.2","peroxisome proliferator-activated receptor gamma, coactivator 1 alpha ",19,2,1,1,0,0,0,0,0,3,"hsa-miR-23c",-0.12,-0.27,0.62,"2005, 2007, 2009, 2011\n"]
["let-7a/let-7c","let-7-5p/98-5p","PPARGC1B","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","ENST00000309241.5","peroxisome proliferator-activated receptor gamma, coactivator 1 beta ",12,2,0,0,2,1,0,0,1,0,"hsa-let-7d-5p",-0.49,-0.51,"> 0.99","2005, 2007, 2009, 2011\n"]
["miR-101","miR-101-3p.1  ","PPARGC1B","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","ENST00000309241.5","peroxisome proliferator-activated receptor gamma, coactivator 1 beta ",12,4,1,2,1,1,0,0,1,0,"hsa-miR-101-3p.1",-0.28,-0.36,"> 0.99",2011]
["mir-22","miR-22-3p   ","PPARGC1B","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","ENST00000309241.5","peroxisome proliferator-activated receptor gamma, coactivator 1 beta ",12,2,0,1,1,2,0,2,0,4,"hsa-miR-22-3p",-0.28,-0.36,0.86,2011]
["mir-23b","miR-23-3p      ","PPP1CB","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000395366.2","protein phosphatase 1, catalytic subunit, beta isozyme ",5795,2,0,1,1,1,1,0,0,3,"hsa-miR-23c",-0.22,-0.47,0.46,"2005, 2007, 2009, 2011\n"]
["mir-148a","miR-148-3p/152-3p","PPP1R10","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","ENST00000376511.2","protein phosphatase 1, regulatory subunit 10 ",893,2,1,1,0,0,0,0,0,0,"hsa-miR-148a-3p",-0.53,-0.54,0.87,2011]
["mir-23b","miR-23-3p      ","PPP1R12A","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000261207.5","protein phosphatase 1, regulatory subunit 12A ",276,2,1,0,1,1,0,1,0,0,"hsa-miR-23a-3p",-0.3,-0.31,0.7,"2005, 2007, 2009, 2011\n"]
["miR-222","miR-221-3p/222-3p     ","PPP3R1","no data","no data","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000234310.3","protein phosphatase 3, regulatory subunit B, alpha ",117,2,0,1,1,0,0,0,0,0,"hsa-miR-222-3p",-0.46,-0.46,0.53,"2005, 2007, 2009, 2011\n"]
["mir-17","miR-17-5p/20-5p/93-5p/106-5p/519-3p","PPP6C","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000373547.4","protein phosphatase 6, catalytic subunit ",346,2,1,1,0,0,0,0,0,2,"hsa-miR-20a-5p",-0.38,-0.56,0.98,"2005, 2007, 2009, 2011\n"]
["miR-222","miR-221-3p/222-3p     ","PPP6C","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000373547.4","protein phosphatase 6, catalytic subunit ",346,2,0,2,0,0,0,0,0,0,"hsa-miR-221-3p",-0.2,-0.34,0.2,"2003, 2005, 2007\n"]
["mir-23b","miR-23-3p      ","PPP6C","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000373547.4","protein phosphatase 6, catalytic subunit ",346,2,0,2,0,1,1,0,0,0,"hsa-miR-23a-3p",-0.07,-0.23,0.36]
["mir-23b","miR-23-3p      ","PRDM1","no data","+","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000369089.3","PR domain containing 1, with ZNF domain ",48,2,1,0,1,0,0,0,0,0,"hsa-miR-23a-3p",-0.14,-0.17,0.36,"2005, 2007, 2009, 2011\n"]
["mir-31/31-5p","miR-31-5p","PRELP","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000343110.2","proline/arginine-rich end leucine-rich repeat protein ",5,2,2,0,0,0,0,0,0,1,"hsa-miR-31-5p",-0.4,-0.4,0.45,2011]
["miR-101","miR-101-3p.1  ","PTCH1","+","+","no data","no data","no data","no data","no data","no data","+","+","+","no data","ENST00000430669.2","patched 1 ",123,2,0,1,1,0,0,0,0,2,"hsa-miR-101-3p.1",-0.2,-0.21,0.75,2011]
["mir-148a","miR-148-3p/152-3p","PTEN","+","+","+","no data","no data","no data","no data","no data","+","no data","+","+","ENST00000371953.3","phosphatase and tensin homolog ",118,2,1,1,0,0,0,0,0,0,"hsa-miR-148a-3p",-0.43,-0.61,0.99,2011]
["mir-23b","miR-23-3p      ","PTEN","+","+","+","no data","no data","no data","no data","no data","+","no data","+","+","ENST00000371953.3","phosphatase and tensin homolog ",118,3,3,0,0,1,1,0,0,1,"hsa-miR-23b-3p",-0.38,-0.52,0.8,2011]
["mir-26a","miR-26-5p  ","PTEN","+","+","+","no data","no data","no data","no data","no data","+","no data","+","+","ENST00000371953.3","phosphatase and tensin homolog ",118,4,3,0,1,0,0,0,0,0,"hsa-miR-26b-5p",-0.55,-0.6,"> 0.99",2011]
["mir-29b","miR-29-3p ","PTEN","+","+","+","no data","no data","no data","no data","no data","+","no data","+","+","ENST00000371953.3","phosphatase and tensin homolog ",118,2,1,1,0,0,0,0,0,0,"hsa-miR-29a-3p",-0.53,-0.6,"> 0.99",2011]
["mir-218","miR-218-5p","PTP4A1","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000370651.3","protein tyrosine phosphatase type IVA, member 1 ",5740,2,0,1,1,0,0,0,0,0,"hsa-miR-218-5p",-0.49,-0.5,0.98,"2005, 2007, 2009, 2011\n"]
["miR-101","miR-101-3p.1  ","PURA","no data","+","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000331327.3","purine-rich element binding protein A ",367,2,0,1,1,1,0,0,1,0,"hsa-miR-101-3p.1",-0.2,-0.3,0.69,"2005, 2007\n"]
["mir-17","miR-17-5p/20-5p/93-5p/106-5p/519-3p","PURA","no data","+","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000331327.3","purine-rich element binding protein A ",367,2,1,0,1,3,1,1,1,1,"hsa-miR-519d-3p",-0.15,-0.28,0.44,"2007, 2011\n"]
["mir-26a","miR-26-5p  ","PURA","no data","+","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000331327.3","purine-rich element binding protein A ",367,2,0,1,1,0,0,0,0,1,"hsa-miR-26a-5p",-0.29,-0.39,0.8,"2007, 2009, 2011\n"]
["miR-101","miR-101-3p.1  ","PURB","no data","+","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000395699.2","purine-rich element binding protein B ",497,2,2,0,0,0,0,0,0,0,"hsa-miR-101-3p.1",-0.2,-0.42,0.94,"2005, 2007, 2009, 2011\n"]
["mir-17","miR-17-5p/20-5p/93-5p/106-5p/519-3p","PURB","no data","+","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000395699.2","purine-rich element binding protein B ",497,2,1,1,0,0,0,0,0,1,"hsa-miR-519d-3p",-0.21,-0.49,0.98,"2005, 2007, 2009, 2011\n"]
["mir-23b","miR-23-3p      ","PURB","no data","+","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000395699.2","purine-rich element binding protein B ",497,2,1,1,0,0,0,0,0,0,"hsa-miR-23c",-0.05,-0.1,0.58,"2009, 2011\n"]
["miR-101","miR-101-3p.1  ","PYGO1","no data","no data","+","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000302000.6","pygopus homolog 1 (Drosophila) ",104,2,0,1,1,3,1,1,1,2,"hsa-miR-101-3p.1",-0.16,-0.58,0.94,"\n"]
["miR-101","miR-101-3p.1  ","QKI","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000392127.2","QKI, KH domain containing, RNA binding ",323,2,0,1,1,3,0,1,2,9,"hsa-miR-101-3p.1",-0.19,-0.31,0.89,"2005, 2007, 2009, 2011\n"]
["mir-143","miR-143-3p ","QKI","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000392127.2","QKI, KH domain containing, RNA binding ",323,2,2,0,0,2,0,1,1,1,"hsa-miR-143-3p",-0.19,-0.42,0.72,2011]
["mir-148a","miR-148-3p/152-3p","QKI","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000392127.2","QKI, KH domain containing, RNA binding ",323,4,3,0,1,0,0,0,0,1,"hsa-miR-148a-3p",-0.67,-1.13,"> 0.99","2005, 2007, 2009, 2011\n"]
["mir-31/31-5p","miR-31-5p","QKI","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000392127.2","QKI, KH domain containing, RNA binding ",323,2,2,0,0,1,0,0,1,3,"hsa-miR-31-5p",-0.27,-0.7,0.49,2011]
["let-7a/let-7c","let-7-5p/98-5p","RAB11FIP4","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000325874.8","RAB11 family interacting protein 4 (class II) ",169,2,0,2,0,0,0,0,0,0,"hsa-let-7f-5p",-0.53,-0.56,"> 0.99","2003, 2005, 2007, 2009, 2011\n"]
["miR-125-5p","miR-125-5p","RAB3D","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","ENST00000222120.3","RAB3D, member RAS oncogene family ",111,2,0,1,1,1,1,0,0,0,"hsa-miR-125b-5p",-0.7,-0.71,0.95,"2005, 2007, 2009, 2011\n"]
["mir-30c","miR-30-5p   ","RAD23B","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000358015.3","RAD23 homolog B (S. cerevisiae) ",1012,2,1,1,0,0,0,0,0,0,"hsa-miR-30c-5p",-0.49,-0.49,0.96,"2005, 2007, 2009, 2011\n"]
["mir-23b","miR-23-3p      ","RAP1A","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000369709.3","RAP1A, member of RAS oncogene family ",382,2,0,0,2,3,1,1,1,0,"hsa-miR-23c",-0.32,-0.5,0.58,"2005, 2007, 2009, 2011\n"]
["miR-101","miR-101-3p.1  ","RAP1B","no data","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000250559.9","RAP1B, member of RAS oncogene family ",3599,2,1,1,0,0,0,0,0,0,"hsa-miR-101-3p.1",-0.66,-0.66,0.93,"2005, 2007, 2009, 2011\n"]
["mir-23b","miR-23-3p      ","RAPGEF2","no data","+","no data","no data","no data","no data","+","no data","+","no data","+","+","ENST00000264431.4","Rap guanine nucleotide exchange factor (GEF) 2 ",484,2,0,1,1,0,0,0,0,0,"hsa-miR-23a-3p",-0.07,-0.07,0.36,"2009, 2011\n"]
["miR-138","miR-138-5p","RARA","+","+","no data","no data","no data","no data","no data","no data","+","+","+","+","ENST00000425707.3","retinoic acid receptor, alpha ",560,2,2,0,0,1,0,1,0,0,"hsa-miR-138-5p",-0.85,-1.08,0.96,"2005, 2007, 2009, 2011\n"]
["mir-30c","miR-30-5p   ","RARG","no data","+","+","no data","no data","no data","no data","no data","+","+","+","+","ENST00000425354.2","retinoic acid receptor, gamma ",21,2,2,0,0,0,0,0,0,0,"hsa-miR-30c-5p",-0.47,-0.47,0.97,"2003, 2005, 2007, 2009, 2011\n"]
["mir-218","miR-218-5p","RASSF2","+","no data","no data","no data","no data","no data","no data","no data","+","+","+","+","ENST00000379400.3","Ras association (RalGDS/AF-6) domain family member 2 ",88,2,2,0,0,2,0,0,2,2,"hsa-miR-218-5p",-0.57,-0.59,0.93,"2009, 2011\n"]
["mir-17","miR-17-5p/20-5p/93-5p/106-5p/519-3p","RBL2","+","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000262133.6","retinoblastoma-like 2 (p130) ",108,2,1,1,0,0,0,0,0,0,"hsa-miR-519d-3p",-0.32,-0.32,0.96,"2005, 2007, 2009, 2011\n"]
["mir-148a","miR-148-3p/152-3p","RBM24","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000379052.5","RNA binding motif protein 24 ",43,2,0,1,1,0,0,0,0,0,"hsa-miR-148a-3p",-0.35,-0.6,0.82,"2005, 2007, 2009, 2011\n"]
["miR-222","miR-221-3p/222-3p     ","RBM24","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000379052.5","RNA binding motif protein 24 ",43,2,0,2,0,0,0,0,0,0,"hsa-miR-221-3p",-0.35,-0.46,0.2,"2003, 2005, 2007, 2009, 2011\n"]
["mir-26a","miR-26-5p  ","REEP3","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000373758.4","receptor accessory protein 3 ",1095,3,1,1,1,1,0,1,0,0,"hsa-miR-26a-5p",-0.62,-0.78,0.97,"2007, 2009, 2011\n"]
["mir-17","miR-17-5p/20-5p/93-5p/106-5p/519-3p","REST","no data","+","no data","no data","no data","no data","no data","no data","+","no data","no data","+","ENST00000309042.7","RE1-silencing transcription factor ",31,2,1,0,1,3,0,1,2,0,"hsa-miR-519d-3p",-0.35,-0.43,0.85,2011]
["mir-218","miR-218-5p","RET","no data","no data","no data","no data","no data","no data","+","no data","+","no data","+","+","ENST00000355710.3","ret proto-oncogene ",5,2,0,1,1,0,0,0,0,1,"hsa-miR-218-5p",-0.47,-0.47,0.97,2011]
["miR-101","miR-101-3p.1  ","RFX3","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000382004.3","regulatory factor X, 3 (influences HLA class II expression) ",37,4,2,1,1,1,0,0,1,1,"hsa-miR-101-3p.1",-0.24,-0.42,0.97,"\n"]
["miR-125-5p","miR-125-5p","RFX3","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000382004.3","regulatory factor X, 3 (influences HLA class II expression) ",37,2,0,1,1,0,0,0,0,0,"hsa-miR-125b-5p",-0.2,-0.34,0.94,"\n"]
["mir-218","miR-218-5p","RFX3","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000382004.3","regulatory factor X, 3 (influences HLA class II expression) ",37,2,1,1,0,0,0,0,0,0,"hsa-miR-218-5p",-0.22,-0.34,0.86,"\n"]
["mir-148a","miR-148-3p/152-3p","RICTOR","no data","+","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000357387.3","RPTOR independent companion of MTOR, complex 2 ",441,2,0,1,1,0,0,0,0,1,"hsa-miR-152-3p",-0.33,-0.33,0.75,"2007, 2009, 2011\n"]
["mir-218","miR-218-5p","RICTOR","no data","+","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000357387.3","RPTOR independent companion of MTOR, complex 2 ",441,2,0,1,1,0,0,0,0,0,"hsa-miR-218-5p",-0.28,-0.31,0.78,"2007, 2009, 2011\n"]
["miR-138","miR-138-5p","RIMS2","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000507740.1","regulating synaptic membrane exocytosis 2 ",8,2,1,0,1,0,0,0,0,1,"hsa-miR-138-5p",-0.5,-0.5,0.91,"2009, 2011\n"]
["mir-218","miR-218-5p","RNF165","no data","no data","no data","+","no data","no data","no data","no data","no data","no data","+","no data","ENST00000269439.7","ring finger protein 165 ",18,2,0,2,0,0,0,0,0,1,"hsa-miR-218-5p",-0.26,-0.26,0.86,"2007, 2009, 2011\n"]
["mir-29b","miR-29-3p ","RNF165","no data","no data","no data","+","no data","no data","no data","no data","no data","no data","+","no data","ENST00000269439.7","ring finger protein 165 ",18,2,0,2,0,0,0,0,0,3,"hsa-miR-29b-3p",-0.19,-0.19,0.91,"2007, 2009, 2011\n"]
["mir-148a","miR-148-3p/152-3p","ROBO1","no data","no data","no data","no data","no data","no data","+","+","+","no data","+","+","ENST00000436010.2","roundabout, axon guidance receptor, homolog 1 (Drosophila) ",546,2,0,2,0,0,0,0,0,0,"hsa-miR-148a-3p",-0.45,-0.45,0.94,"2005, 2007, 2009, 2011\n"]
["mir-23b","miR-23-3p      ","ROBO2","no data","no data","no data","no data","no data","no data","no data","+","+","no data","+","+","ENST00000461745.1","roundabout, axon guidance receptor, homolog 2 (Drosophila) ",22,2,1,0,1,1,0,1,0,1,"hsa-miR-23c",-0.11,-0.12,0.69,"2007, 2009, 2011\n"]
["mir-148a","miR-148-3p/152-3p","ROCK1","no data","no data","no data","no data","no data","no data","+","no data","+","no data","+","+","ENST00000399799.2","Rho-associated, coiled-coil containing protein kinase 1 ",7,2,0,1,1,0,0,0,0,1,"hsa-miR-148a-3p",-0.41,-0.41,"> 0.99","2007, 2009, 2011\n"]
["miR-101","miR-101-3p.1  ","RORA","no data","+","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000335670.6","RAR-related orphan receptor A ",102,2,1,1,0,1,0,0,1,1,"hsa-miR-101-3p.1",-0.31,-0.38,0.88,2011]
["miR-125-5p","miR-125-5p","RORA","no data","+","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000335670.6","RAR-related orphan receptor A ",102,2,2,0,0,0,0,0,0,0,"hsa-miR-125a-5p",-0.2,-0.24,"> 0.99",2011]
["mir-23b","miR-23-3p      ","RORA","no data","+","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000335670.6","RAR-related orphan receptor A ",102,2,1,1,0,2,0,0,2,3,"hsa-miR-23c",-0.26,-0.3,0.72,2011]
["mir-29b","miR-29-3p ","RORA","no data","+","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000335670.6","RAR-related orphan receptor A ",102,2,1,0,1,0,0,0,0,0,"hsa-miR-29b-3p",-0.22,-0.27,0.99,2011]
["miR-138","miR-138-5p","RPRD1B","+","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000373433.4","regulation of nuclear pre-mRNA domain containing 1B ",1140,2,0,0,2,0,0,0,0,0,"hsa-miR-138-5p",-0.44,-0.44,0.9,"2009, 2011\n"]
["mir-218","miR-218-5p","RPS6KA3","+","no data","no data","no data","no data","no data","no data","no data","+","no data","+","+","ENST00000379565.3","ribosomal protein S6 kinase, 90kDa, polypeptide 3 ",769,2,0,1,1,0,0,0,0,1,"hsa-miR-218-5p",-0.41,-0.43,0.98,"2005, 2007, 2009, 2011\n"]
["mir-17","miR-17-5p/20-5p/93-5p/106-5p/519-3p","RRAGD","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000369415.4","Ras-related GTP binding D ",644,2,0,2,0,3,0,2,1,3,"hsa-miR-519d-3p",-0.49,-0.6,0.94,"2005, 2007, 2009, 2011\n"]
["mir-26a","miR-26-5p  ","RTF1","no data","no data","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000389629.4","Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) ",1869,2,1,1,0,0,0,0,0,0,"hsa-miR-26a-5p",-0.24,-0.28,0.86,"2007, 2009, 2011\n"]
["miR-101","miR-101-3p.1  ","RUNX1","no data","+","+","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000344691.4","runt-related transcription factor 1 ",182,2,0,0,2,0,0,0,0,1,"hsa-miR-101-3p.1",-0.04,-0.07,0.66,2011]
["mir-23b","miR-23-3p      ","RUNX1T1","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000523629.1","runt-related transcription factor 1; translocated to, 1 (cyclin D-related) ",9,2,1,0,1,0,0,0,0,1,"hsa-miR-23a-3p",-0.04,-0.04,0.62,"2005, 2007, 2009, 2011\n"]
["mir-148a","miR-148-3p/152-3p","S1PR1","no data","+","no data","no data","no data","no data","no data","no data","+","+","+","no data","ENST00000305352.6","sphingosine-1-phosphate receptor 1 ",251,2,1,1,0,0,0,0,0,0,"hsa-miR-148b-3p",-0.68,-0.68,0.94,"2005, 2007, 2009, 2011\n"]
["miR-125-5p","miR-125-5p","SARM1","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","+","+","ENST00000457710.3","sterile alpha and TIR motif containing 1 ",130,2,2,0,0,1,0,1,0,2,"hsa-miR-125b-5p",-0.15,-0.23,0.27,"2005, 2007, 2009, 2011\n"]
["mir-23b","miR-23-3p      ","SATB1","no data","+","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000338745.6","SATB homeobox 1 ",312,2,2,0,0,1,0,0,1,0,"hsa-miR-23a-3p",-0.51,-0.66,0.89,"2005, 2007, 2009, 2011\n"]
["mir-31/31-5p","miR-31-5p","SATB2","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","+","no data","ENST00000417098.1","SATB homeobox 2 ",820,2,1,1,0,0,0,0,0,0,"hsa-miR-31-5p",-0.34,-0.38,0.71,"2007, 2009, 2011\n"]
["miR-125-5p","miR-125-5p","SEMA4F","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000357877.2","sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F ",32,2,0,2,0,1,0,0,1,1,"hsa-miR-125a-5p",-0.33,-0.68,0.95,2011]
["miR-222","miR-221-3p/222-3p     ","SEMA6D","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000355997.3","sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D ",179,2,0,1,1,0,0,0,0,1,"hsa-miR-222-3p",-0.21,-0.22,0.44,"2005, 2007\n"]
["mir-23b","miR-23-3p      ","SEMA6D","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000355997.3","sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D ",179,3,2,1,0,2,1,1,0,3,"hsa-miR-23a-3p",-0.3,-0.32,0.82,"2005, 2007, 2009, 2011\n"]
["mir-31/31-5p","miR-31-5p","SEMA6D","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000355997.3","sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D ",179,2,1,0,1,0,0,0,0,2,"hsa-miR-31-5p",-0.47,-0.49,0.46,"2007, 2011\n"]
["let-7a/let-7c","let-7-5p/98-5p","SENP2","no data","no data","+","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000296257.5","SUMO1/sentrin/SMT3 specific peptidase 2 ",1693,2,1,0,1,0,0,0,0,0,"hsa-let-7d-5p",-0.34,-0.65,0.99,"2005, 2007, 2009, 2011\n"]
["mir-17","miR-17-5p/20-5p/93-5p/106-5p/519-3p","SERP1","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000239944.2","stress-associated endoplasmic reticulum protein 1 ",3242,2,1,1,0,0,0,0,0,0,"hsa-miR-519d-3p",-0.62,-0.77,0.96,"2005, 2007, 2009, 2011\n"]
["mir-148a","miR-148-3p/152-3p","SFMBT1","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000394752.3","Scm-like with four mbt domains 1 ",116,2,0,1,1,0,0,0,0,1,"hsa-miR-148a-3p",-0.27,-0.32,0.8,2011]
["miR-125-5p","miR-125-5p","SGPL1","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","+","+","ENST00000373202.3","sphingosine-1-phosphate lyase 1 ",105,2,1,1,0,0,0,0,0,1,"hsa-miR-125b-5p",-0.45,-0.56,"> 0.99","2005, 2007, 2009, 2011\n"]
["miR-138","miR-138-5p","SH2B3","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000341259.2","SH2B adaptor protein 3 ",89,2,1,0,1,1,0,1,0,0,"hsa-miR-138-5p",-0.67,-0.82,"> 0.99","2007, 2009, 2011\n"]
["mir-26a","miR-26-5p  ","SH3D19","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000409598.4","SH3 domain containing 19 ",245,2,0,1,1,0,0,0,0,0,"hsa-miR-26b-5p",-0.23,-0.29,0.91,"2007, 2009, 2011\n"]
["mir-143","miR-143-3p ","SH3PXD2A","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","ENST00000369774.4","SH3 and PX domains 2A ",152,3,1,1,1,0,0,0,0,0,"hsa-miR-143-3p",-0.06,-0.07,0.86,"2007, 2009, 2011\n"]
["mir-26a","miR-26-5p  ","SH3PXD2A","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","ENST00000369774.4","SH3 and PX domains 2A ",152,2,1,0,1,0,0,0,0,0,"hsa-miR-26a-5p",-0.03,-0.04,0.97,"2007, 2009, 2011\n"]
["mir-29b","miR-29-3p ","SH3PXD2A","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","ENST00000369774.4","SH3 and PX domains 2A ",152,2,1,1,0,1,0,1,0,1,"hsa-miR-29b-3p",-0.34,-0.41,"> 0.99","2007, 2009, 2011\n"]
["miR-101","miR-101-3p.1  ","SHISA6","no data","no data","+","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000441885.3","shisa family member 6 ",5,2,1,0,1,0,0,0,0,0,"hsa-miR-101-3p.1",-0.32,-0.32,0.89,2011]
["mir-218","miR-218-5p","SHISA6","no data","no data","+","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000441885.3","shisa family member 6 ",5,2,1,1,0,0,0,0,0,0,"hsa-miR-218-5p",-0.43,-0.43,"> 0.99",2011]
["miR-138","miR-138-5p","SIN3A","+","no data","no data","no data","no data","no data","no data","no data","+","no data","+","+","ENST00000394947.3","SIN3 transcription regulator family member A ",1142,2,1,1,0,1,0,0,1,0,"hsa-miR-138-5p",-0.83,-1.02,"> 0.99","2003, 2005, 2007, 2009, 2011\n"]
["miR-101","miR-101-3p.1  ","SIX4","no data","+","no data","no data","no data","no data","no data","no data","+","no data","+","+","ENST00000216513.4","SIX homeobox 4 ",94,2,2,0,0,0,0,0,0,2,"hsa-miR-101-3p.1",-0.28,-0.41,0.83,"2007, 2009, 2011\n"]
["let-7a/let-7c","let-7-5p/98-5p","SKIL","+","no data","no data","-","no data","no data","no data","no data","+","no data","+","+","ENST00000458537.3","SKI-like oncogene ",210,3,1,0,2,0,0,0,0,0,"hsa-let-7d-5p",-0.49,-0.77,"> 0.99","\n"]
["miR-21","miR-21-5p/590-5p  ","SKP2","+","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","ENST00000274255.6","S-phase kinase-associated protein 2, E3 ubiquitin protein ligase ",340,2,2,0,0,0,0,0,0,0,"hsa-miR-21-5p",-0.47,-0.47,"< 0.1"]
["miR-125-5p","miR-125-5p","SLC35C1","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000314134.3","solute carrier family 35 (GDP-fucose transporter), member C1 ",856,2,0,2,0,0,0,0,0,0,"hsa-miR-125b-5p",-0.22,-0.28,0.79,2011]
["mir-26a","miR-26-5p  ","SLC7A11","no data","+","no data","no data","no data","no data","no data","no data","+","no data","+","+","ENST00000280612.5","solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 ",61,2,2,0,0,2,1,0,1,1,"hsa-miR-26a-5p",-0.08,-0.52,0.73,"2007, 2009, 2011\n"]
["mir-26a","miR-26-5p  ","SMAD1","no data","+","no data","+","no data","+","+","no data","+","+","+","no data","ENST00000302085.4","SMAD family member 1 ",240,2,1,1,0,0,0,0,0,0,"hsa-miR-26a-5p",-0.54,-0.54,0.93,"2003, 2005, 2007, 2009, 2011\n"]
["let-7a/let-7c","let-7-5p/98-5p","SMC1A","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000322213.4","structural maintenance of chromosomes 1A ",1626,2,2,0,0,2,1,1,0,0,"hsa-let-7a-5p",-0.51,-0.7,0.98,"2009, 2011\n"]
["mir-218","miR-218-5p","SMPD3","+","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000219334.5","sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) ",9,2,0,1,1,0,0,0,0,0,"hsa-miR-218-5p",-0.32,-0.32,0.95,"2005, 2007, 2009, 2011\n"]
["mir-26a","miR-26-5p  ","SOCS5","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000306503.5","suppressor of cytokine signaling 5 ",72,3,1,1,1,1,0,1,0,4,"hsa-miR-26a-5p",-0.16,-0.21,0.86,"2005, 2007\n"]
["mir-29b","miR-29-3p ","SOCS7","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000577233.1","suppressor of cytokine signaling 7 ",15,2,0,2,0,1,0,1,0,0,"hsa-miR-29b-3p",-0.02,-0.22,0.96,2011]
["mir-31/31-5p","miR-31-5p","SOX11","+","+","no data","+","+","no data","no data","no data","+","+","+","+","ENST00000322002.3","SRY (sex determining region Y)-box 11 ",1100,2,1,0,1,1,0,1,0,0,"hsa-miR-31-5p",-0.3,-0.44,0.43,"2009, 2011\n"]
["mir-29b","miR-29-3p ","SPARC","no data","+","no data","no data","no data","no data","no data","no data","no data","+","+","no data","ENST00000231061.4","secreted protein, acidic, cysteine-rich (osteonectin) ",2467,2,0,0,2,1,0,1,0,0,"hsa-miR-29a-3p",-0.67,-0.75,"> 0.99","2005, 2007, 2009, 2011\n"]
["mir-30c","miR-30-5p   ","SPAST","+","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000315285.3","spastin ",239,2,1,0,1,0,0,0,0,1,"hsa-miR-30c-5p",-0.28,-0.32,0.99,"2005, 2007, 2009, 2011\n"]
["miR-101","miR-101-3p.1  ","SPRED1","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","+","no data","ENST00000299084.4","sprouty-related, EVH1 domain containing 1 ",547,2,1,1,0,0,0,0,0,3,"hsa-miR-101-3p.1",-0.34,-0.49,0.93,"2005, 2007, 2009, 2011\n"]
["mir-17","miR-17-5p/20-5p/93-5p/106-5p/519-3p","SPRED1","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","+","no data","ENST00000299084.4","sprouty-related, EVH1 domain containing 1 ",547,2,0,2,0,0,0,0,0,1,"hsa-miR-519d-3p",-0.09,-0.38,0.88,2011]
["mir-17","miR-17-5p/20-5p/93-5p/106-5p/519-3p","SPRY4","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","+","no data","ENST00000344120.4","sprouty homolog 4 (Drosophila) ",110,2,0,2,0,0,0,0,0,1,"hsa-miR-519d-3p",-0.15,-0.16,0.84,"2005, 2007, 2009, 2011\n"]
["miR-125-5p","miR-125-5p","SPTBN2","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","+","no data","ENST00000529997.1","spectrin, beta, non-erythrocytic 2 ",910,2,1,1,0,0,0,0,0,2,"hsa-miR-125a-5p",-0.04,-0.05,0.69,"\n"]
["miR-138","miR-138-5p","SRRM4","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000267260.4","serine/arginine repetitive matrix 4 ",22,3,0,2,1,0,0,0,0,0,"hsa-miR-138-5p",-0.69,-0.69,0.97,"2005, 2007, 2009, 2011\n"]
["miR-125-5p","miR-125-5p","SSTR3","no data","+","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000328544.3","somatostatin receptor 3 ",5,2,2,0,0,1,0,1,0,2,"hsa-miR-125b-5p",-0.68,-0.68,"> 0.99",2011]
["miR-101","miR-101-3p.1  ","STC1","no data","+","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","ENST00000290271.2","stanniocalcin 1 ",2932,3,2,1,0,0,0,0,0,0,"hsa-miR-101-3p.1",-0.97,-1,0.96,"2005, 2007, 2009, 2011\n"]
["mir-26a","miR-26-5p  ","STK39","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","no data","no data","ENST00000355999.4","serine threonine kinase 39 ",266,3,1,0,2,0,0,0,0,0,"hsa-miR-26b-5p",-0.49,-0.66,0.96,"2005, 2007, 2009, 2011\n"]
["mir-31/31-5p","miR-31-5p","STK40","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","+","+","ENST00000359297.2","serine/threonine kinase 40 ",214,2,2,0,0,1,0,1,0,2,"hsa-miR-31-5p",-0.4,-0.44,0.82,"2007, 2009, 2011\n"]
["miR-138","miR-138-5p","STOX2","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000308497.4","storkhead box 2 ",379,2,0,1,1,2,0,1,1,0,"hsa-miR-138-5p",-0.59,-0.6,0.81,"\n"]
["mir-26a","miR-26-5p  ","STRADB","+","no data","no data","no data","no data","no data","+","no data","no data","no data","+","+","ENST00000392249.2","STE20-related kinase adaptor beta ",12,2,1,1,0,1,0,0,1,0,"hsa-miR-26a-5p",-0.85,-0.85,0.96,"2007, 2009, 2011\n"]
["mir-17","miR-17-5p/20-5p/93-5p/106-5p/519-3p","STRBP","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000447404.2","spermatid perinuclear RNA binding protein ",575,2,1,0,1,0,0,0,0,2,"hsa-miR-93-5p",-0.03,-0.08,0.21,"\n"]
["mir-26a","miR-26-5p  ","STRBP","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000447404.2","spermatid perinuclear RNA binding protein ",575,2,0,1,1,0,0,0,0,1,"hsa-miR-26b-5p",-0.5,-0.5,0.83,"2005, 2007, 2009, 2011\n"]
["mir-23b","miR-23-3p      ","STRN","no data","+","+","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000263918.4","striatin, calmodulin binding protein ",476,2,2,0,0,0,0,0,0,2,"hsa-miR-23a-3p",-0.05,-0.09,0.85,2011]
["mir-29b","miR-29-3p ","STRN","no data","+","+","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000263918.4","striatin, calmodulin binding protein ",476,2,0,2,0,0,0,0,0,0,"hsa-miR-29a-3p",-0.23,-0.41,0.94,2011]
["mir-26a","miR-26-5p  ","SULF1","no data","+","+","+","no data","no data","no data","no data","no data","+","+","+","ENST00000458141.2","sulfatase 1 ",11,2,1,0,1,0,0,0,0,1,"hsa-miR-26a-5p",-0.32,-0.32,0.89,"2007, 2009, 2011\n"]
["miR-101","miR-101-3p.1  ","SYNCRIP","no data","no data","no data","no data","no data","no data","no data","no data","+","+","no data","no data","ENST00000355238.6","synaptotagmin binding, cytoplasmic RNA interacting protein ",4864,2,1,0,1,2,0,1,1,2,"hsa-miR-101-3p.1",-0.32,-0.49,0.93,2011]
["mir-29b","miR-29-3p ","SYNCRIP","no data","no data","no data","no data","no data","no data","no data","no data","+","+","no data","no data","ENST00000355238.6","synaptotagmin binding, cytoplasmic RNA interacting protein ",4864,2,0,2,0,1,0,0,1,0,"hsa-miR-29a-3p",-0.17,-0.46,0.92,2011]
["miR-125-5p","miR-125-5p","SYT7","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","ENST00000263846.4","synaptotagmin VII ",192,2,0,2,0,2,0,2,0,0,"hsa-miR-125b-5p",-0.05,-0.23,0.64,"\n"]
["mir-218","miR-218-5p","TANC2","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000424789.2","tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 ",155,3,1,0,2,0,0,0,0,1,"hsa-miR-218-5p",-0.11,-0.12,"> 0.99","2009, 2011\n"]
["mir-17","miR-17-5p/20-5p/93-5p/106-5p/519-3p","TAOK1","+","no data","no data","no data","no data","no data","+","no data","no data","no data","no data","+","ENST00000261716.3","TAO kinase 1 ",164,2,0,2,0,2,0,1,1,4,"hsa-miR-519d-3p",-0.24,-0.26,0.92,2011]
["let-7a/let-7c","let-7-5p/98-5p","TARBP2","no data","+","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000552857.1","TAR (HIV-1) RNA binding protein 2 ",1553,2,0,1,1,0,0,0,0,0,"hsa-let-7d-5p",-0.62,-0.62,0.7,"2009, 2011\n"]
["mir-17","miR-17-5p/20-5p/93-5p/106-5p/519-3p","TBL1X","no data","no data","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000407597.2","transducin (beta)-like 1X-linked ",125,2,0,2,0,0,0,0,0,1,"hsa-miR-519d-3p",-0.12,-0.13,0.93,"2005, 2007, 2009, 2011\n"]
["miR-101","miR-101-3p.1  ","TCF4","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000354452.3","transcription factor 4 ",394,2,1,0,1,0,0,0,0,1,"hsa-miR-101-3p.1",-0.08,-0.28,0.35,"2009, 2011\n"]
["miR-138","miR-138-5p","TCF4","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000354452.3","transcription factor 4 ",394,2,0,1,1,0,0,0,0,0,"hsa-miR-138-5p",-0.52,-0.59,0.8,"2009, 2011\n"]
["mir-23b","miR-23-3p      ","TENM1","no data","+","no data","no data","no data","no data","+","no data","no data","no data","+","no data","ENST00000371130.3","teneurin transmembrane protein 1 ",5,2,0,2,0,1,0,0,1,0,"hsa-miR-23a-3p",-0.05,-0.05,0.49,"2007, 2009, 2011\n"]
["mir-26a","miR-26-5p  ","TET1","no data","+","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000373644.4","tet methylcytosine dioxygenase 1 ",5,2,0,1,1,2,0,0,2,0,"hsa-miR-26b-5p",-0.36,-0.36,0.87,"2005, 2007, 2009, 2011\n"]
["mir-29b","miR-29-3p ","TET1","no data","+","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000373644.4","tet methylcytosine dioxygenase 1 ",5,4,0,3,1,0,0,0,0,1,"hsa-miR-29a-3p",-1.78,-1.78,"> 0.99","2005, 2007, 2009, 2011\n"]
["let-7a/let-7c","let-7-5p/98-5p","TET2","+","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000545826.1","tet methylcytosine dioxygenase 2 ",558,2,0,0,2,0,0,0,0,0,"hsa-let-7d-5p",-0.23,-0.23,0.96,2011]
["miR-101","miR-101-3p.1  ","TET2","+","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000545826.1","tet methylcytosine dioxygenase 2 ",558,3,2,0,1,2,0,0,2,1,"hsa-miR-101-3p.1",-0.47,-0.47,0.89,2011]
["miR-125-5p","miR-125-5p","TET2","+","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000545826.1","tet methylcytosine dioxygenase 2 ",558,3,0,1,2,0,0,0,0,1,"hsa-miR-125a-5p",-0.57,-0.57,0.91,2011]
["miR-138","miR-138-5p","TET2","+","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000545826.1","tet methylcytosine dioxygenase 2 ",558,2,1,0,1,1,0,1,0,1,"hsa-miR-138-5p",-0.3,-0.3,0.37,2011]
["mir-26a","miR-26-5p  ","TET2","+","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000545826.1","tet methylcytosine dioxygenase 2 ",558,5,2,1,2,1,0,0,1,0,"hsa-miR-26b-5p",-0.52,-0.52,"> 0.99",2011]
["mir-29b","miR-29-3p ","TET2","+","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000545826.1","tet methylcytosine dioxygenase 2 ",558,4,2,2,0,0,0,0,0,0,"hsa-miR-29a-3p",-1.17,-1.17,"> 0.99",2011]
["let-7a/let-7c","let-7-5p/98-5p","TET3","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000409262.3","tet methylcytosine dioxygenase 3 ",1437,3,1,0,2,0,0,0,0,0,"hsa-let-7d-5p",-0.45,-0.45,"> 0.99","2009, 2011\n"]
["mir-17","miR-17-5p/20-5p/93-5p/106-5p/519-3p","TET3","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","ENST00000409262.3","tet methylcytosine dioxygenase 3 ",1437,2,0,2,0,2,0,0,2,1,"hsa-miR-20a-5p",-0.25,-0.26,0.95,"2009, 2011\n"]
["mir-23b","miR-23-3p      ","TET3","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","ENST00000409262.3","tet methylcytosine dioxygenase 3 ",1437,3,1,2,0,2,0,0,2,0,"hsa-miR-23a-3p",-0.09,-0.09,0.55,"2009, 2011\n"]
["mir-26a","miR-26-5p  ","TET3","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","ENST00000409262.3","tet methylcytosine dioxygenase 3 ",1437,3,2,0,1,1,0,1,0,0,"hsa-miR-26a-5p",-0.17,-0.17,"> 0.99","2009, 2011\n"]
["mir-29b","miR-29-3p ","TET3","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","ENST00000409262.3","tet methylcytosine dioxygenase 3 ",1437,8,3,4,1,4,0,3,1,1,"hsa-miR-29a-3p",-2.16,-2.17,"> 0.99","2009, 2011\n"]
["mir-26a","miR-26-5p  ","TFAP2A","no data","+","no data","no data","no data","no data","no data","no data","+","+","+","+","ENST00000379613.3","transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) ",367,2,0,0,2,0,0,0,0,1,"hsa-miR-26b-5p",-0.34,-0.37,0.87,"2007, 2009, 2011\n"]
["let-7a/let-7c","let-7-5p/98-5p","TGFBR1","+","+","no data","no data","no data","+","no data","no data","+","no data","+","+","ENST00000374994.4","transforming growth factor, beta receptor 1 ",249,2,1,0,1,0,0,0,0,1,"hsa-let-7d-5p",-0.72,-0.76,"> 0.99","2005, 2007, 2009, 2011\n"]
["miR-101","miR-101-3p.1  ","TGFBR1","+","+","no data","no data","no data","+",null,"no data","+","no data","+","+","ENST00000374994.4","transforming growth factor, beta receptor 1 ",249,2,1,1,0,0,0,0,0,1,"hsa-miR-101-3p.1",-0.49,-0.53,0.88,"2005, 2007, 2009, 2011\n"]
["miR-21","miR-21-5p/590-5p  ","TGFBR2","no data","+","no data","no data","no data","+","no data","+","+","no data","+","+","ENST00000359013.4","transforming growth factor, beta receptor II (70/80kDa) ",2168,2,0,1,1,0,0,0,0,3,"hsa-miR-21-5p",-0.13,-0.17,0.63,"2007, 2009, 2011\n"]
["miR-222","miR-221-3p/222-3p     ","THBS1","+","+","no data","no data","no data","no data","+","no data","+","no data","+","+","ENST00000260356.5","thrombospondin 1 ",46844,2,1,1,0,0,0,0,0,0,"hsa-miR-221-3p",-0.32,-0.32,0.65,"2009, 2011\n"]
["let-7a/let-7c","let-7-5p/98-5p","THRA","no data","no data","no data","no data","no data","no data","no data","no data","+","+","+","+","ENST00000450525.2","thyroid hormone receptor, alpha ",547,2,0,1,1,0,0,0,0,0,"hsa-let-7d-5p",-0.44,-0.44,0.95,"\n"]
["mir-17","miR-17-5p/20-5p/93-5p/106-5p/519-3p","THRA","no data","no data","no data","no data","no data","no data","no data","no data","+","+","+","+","ENST00000450525.2","thyroid hormone receptor, alpha ",547,2,0,2,0,0,0,0,0,0,"hsa-miR-20a-5p",-0.31,-0.31,0.92,"2005, 2007, 2009, 2011\n"]
["mir-29b","miR-29-3p ","THRA","no data","no data","no data","no data","no data","no data","no data","no data","+","+","+","+","ENST00000450525.2","thyroid hormone receptor, alpha ",547,2,1,1,0,0,0,0,0,4,"hsa-miR-29b-3p",-0.34,-0.34,0.98,"\n"]
["miR-138","miR-138-5p","THRB","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","+","+","ENST00000396671.2","thyroid hormone receptor, beta ",55,2,1,1,0,0,0,0,0,0,"hsa-miR-138-5p",-0.49,-0.79,"> 0.99","2007, 2009, 2011\n"]
["miR-21","miR-21-5p/590-5p  ","THRB","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","+","+","ENST00000396671.2","thyroid hormone receptor, beta ",55,2,0,2,0,0,0,0,0,0,"hsa-miR-21-5p",-0.26,-0.41,0.77,"2007, 2009, 2011\n"]
["mir-23b","miR-23-3p      ","TLK1","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000431350.2","tousled-like kinase 1 ",200,3,2,1,0,0,0,0,0,0,"hsa-miR-23a-3p",-0.15,-0.32,0.71,"2005, 2007, 2009, 2011\n"]
["miR-125-5p","miR-125-5p","TMEM120B","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000449592.2","transmembrane protein 120B ",60,2,2,0,0,1,1,0,0,2,"hsa-miR-125a-5p",-0.37,-0.71,0.96,2011]
["mir-23b","miR-23-3p      ","TMEM170B","no data","no data","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000379426.1","transmembrane protein 170B ",489,2,0,1,1,0,0,0,0,4,"hsa-miR-23b-3p",-0.18,-0.31,0.35,"2009, 2011\n"]
["mir-148a","miR-148-3p/152-3p","TNRC6A","no data","no data","+","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000395799.3","trinucleotide repeat containing 6A ",267,2,1,0,1,0,0,0,0,0,"hsa-miR-148a-3p",-0.56,-0.56,0.93,"2005, 2007, 2009, 2011\n"]
["mir-23b","miR-23-3p      ","TNRC6A","no data","no data","+","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000395799.3","trinucleotide repeat containing 6A ",267,2,1,1,0,1,0,1,0,0,"hsa-miR-23c",-0.39,-0.41,0.7,"2005, 2007, 2009, 2011\n"]
["miR-101","miR-101-3p.1  ","TNRC6B","no data","no data","+","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000335727.9","trinucleotide repeat containing 6B ",69,2,2,0,0,0,0,0,0,3,"hsa-miR-101-3p.1",-0.04,-0.06,0.93,"2007, 2009, 2011\n"]
["mir-23b","miR-23-3p      ","TNRC6B","no data","no data","+","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000335727.9","trinucleotide repeat containing 6B ",69,2,2,0,0,0,0,0,0,0,"hsa-miR-23a-3p",-0.12,-0.15,0.78,"2007, 2009, 2011\n"]
["mir-26a","miR-26-5p  ","TNRC6B","no data","no data","+","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000335727.9","trinucleotide repeat containing 6B ",69,2,2,0,0,0,0,0,0,5,"hsa-miR-26b-5p",-0.11,-0.12,0.98,"2007, 2009, 2011\n"]
["mir-148a","miR-148-3p/152-3p","TNRC6C","no data","no data","+","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000335749.4","trinucleotide repeat containing 6C ",248,2,1,0,1,0,0,0,0,0,"hsa-miR-148a-3p",-0.4,-0.42,0.98,2011]
["mir-23b","miR-23-3p      ","TNRC6C","no data","no data","+","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000335749.4","trinucleotide repeat containing 6C ",248,2,1,1,0,0,0,0,0,0,"hsa-miR-23a-3p",-0.05,-0.05,0.74,2011]
["let-7a/let-7c","let-7-5p/98-5p","TP53","+","+","no data","no data","no data","no data","no data","no data","+","no data","+","+","ENST00000420246.2","tumor protein p53 ",836,2,1,1,0,0,0,0,0,0,"hsa-let-7d-5p",-0.64,-0.64,0.88,2011]
["mir-22","miR-22-3p   ","TP53INP1","+","+","no data","no data","no data","no data","no data","no data","+","no data","no data","+","ENST00000448464.2","tumor protein p53 inducible nuclear protein 1 ",39,2,0,2,0,0,0,0,0,1,"hsa-miR-22-3p",-0.29,-0.78,0.91,"2005, 2007, 2009, 2011\n"]
["mir-26a","miR-26-5p  ","TP53INP1","+","+","no data","no data","no data","no data","no data","no data","+","no data","no data","+","ENST00000448464.2","tumor protein p53 inducible nuclear protein 1 ",39,2,0,1,1,2,0,0,2,2,"hsa-miR-26b-5p",-0.36,-0.63,0.92,"2005, 2007, 2009, 2011\n"]
["miR-138","miR-138-5p","TP53INP2","no data","no data","no data","no data","no data","no data","no data","no data","+","+","no data","no data","ENST00000374810.3","tumor protein p53 inducible nuclear protein 2 ",12,2,1,0,1,1,0,1,0,0,"hsa-miR-138-5p",-0.68,-0.68,0.99,"2005, 2007, 2009, 2011\n"]
["mir-218","miR-218-5p","TPD52","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","no data","ENST00000379096.5","tumor protein D52 ",4585,2,0,2,0,2,0,1,1,2,"hsa-miR-218-5p",-0.81,-0.84,0.98,"2009, 2011\n"]
["mir-29b","miR-29-3p ","TRAF4","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","+","ENST00000262395.5","TNF receptor-associated factor 4 ",3123,2,0,1,1,0,0,0,0,0,"hsa-miR-29a-3p",-0.54,-0.54,0.88,"2005, 2007, 2009, 2011\n"]
["mir-146b-5p","mir-146b-5p","TRAF6","no data","+","no data","no data","no data","no data","+","no data","+","+","+","+","ENST00000526995.1","TNF receptor-associated factor 6, E3 ubiquitin protein ligase ",91,3,3,0,0,3,0,1,2,1,"hsa-miR-146b-5p",-0.49,-1,0.16,"2003, 2005, 2007, 2009, 2011\n"]
["mir-26a","miR-26-5p  ","TRERF1","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000541110.1","transcriptional regulating factor 1 ",52,2,1,0,1,0,0,0,0,0,"hsa-miR-26a-5p",-0.1,-0.1,0.9,2011]
["mir-29b","miR-29-3p ","TRIB2","no data","no data","no data","no data","no data","no data","+","no data","+","no data","no data","no data","ENST00000155926.4","tribbles pseudokinase 2 ",68,3,0,2,1,0,0,0,0,0,"hsa-miR-29a-3p",-0.96,-0.96,"> 0.99","2005, 2007, 2009, 2011\n"]
["let-7a/let-7c","let-7-5p/98-5p","TRIM71","+","+","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000383763.5","tripartite motif containing 71, E3 ubiquitin protein ligase ",67,7,4,1,2,1,0,1,0,0,"hsa-let-7d-5p",-1.39,-1.66,"> 0.99","2007, 2009, 2011\n"]
["miR-125-5p","miR-125-5p","TRIM71","+","+","no data","no data","no data","no data",null,"no data","no data","+","no data","no data","ENST00000383763.5","tripartite motif containing 71, E3 ubiquitin protein ligase ",67,2,1,0,1,2,1,0,1,0,"hsa-miR-125a-5p",-0.74,-0.74,"> 0.99","2007, 2009, 2011\n"]
["mir-218","miR-218-5p","TRIM71","+","+","no data","no data","no data","no data","no data","no data","no data","+","no data","no data","ENST00000383763.5","tripartite motif containing 71, E3 ubiquitin protein ligase ",67,2,1,1,0,0,0,0,0,3,"hsa-miR-218-5p",-0.38,-0.43,0.99,"\n"]
["miR-101","miR-101-3p.1  ","TSHZ3","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000240587.4","teashirt zinc finger homeobox 3 ",81,2,2,0,0,0,0,0,0,0,"hsa-miR-101-3p.1",-0.39,-0.67,0.92,"2007, 2009, 2011\n"]
["miR-138","miR-138-5p","TUBB6","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000591208.1","tubulin, beta 6 class V ",5820,2,0,1,1,1,0,1,0,1,"hsa-miR-138-5p",-0.44,-0.52,"< 0.1","\n"]
["mir-148a","miR-148-3p/152-3p","TXNIP","+","+","no data","no data","no data","no data","no data","no data","+","no data","no data","+","ENST00000369317.4","thioredoxin interacting protein ",11,2,0,1,1,0,0,0,0,0,"hsa-miR-148b-3p",-0.21,-0.51,0.78,2011]
["mir-23b","miR-23-3p      ","TXNRD1","no data","+","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000378070.4","thioredoxin reductase 1 ",1255,2,1,0,1,0,0,0,0,0,"hsa-miR-23c",-0.32,-0.34,0.69,"2009, 2011\n"]
["mir-22","miR-22-3p   ","TYRO3","no data","no data","+","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000263798.3","TYRO3 protein tyrosine kinase ",70,2,0,2,0,0,0,0,0,1,"hsa-miR-22-3p",-0.48,-0.48,0.96,"2005, 2007, 2009, 2011\n"]
["miR-101","miR-101-3p.1  ","UBE2D1","+","no data","no data","+","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000373910.4","ubiquitin-conjugating enzyme E2D 1 ",200,2,1,0,1,2,0,0,2,1,"hsa-miR-101-3p.1",-0.97,-0.97,0.87,"2005, 2007, 2009, 2011\n"]
["mir-148a","miR-148-3p/152-3p","UBE2D3","no data","no data","no data","+","no data","no data","no data","no data","no data","no data","no data","+","ENST00000453744.2","ubiquitin-conjugating enzyme E2D 3 ",2312,2,0,1,1,0,0,0,0,0,"hsa-miR-148a-3p",-0.31,-0.6,0.72,"2005, 2007, 2009, 2011\n"]
["mir-148a","miR-148-3p/152-3p","UHMK1","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000538489.1","U2AF homology motif (UHM) kinase 1 ",48,2,0,1,1,1,0,0,1,3,"hsa-miR-148a-3p",-0.37,-0.72,0.94,"2005, 2007, 2011\n"]
["mir-26a","miR-26-5p  ","USP15","no data","no data","no data","+","no data","+","no data","no data","no data","no data","no data","no data","ENST00000353364.3","ubiquitin specific peptidase 15 ",286,2,1,0,1,0,0,0,0,5,"hsa-miR-26a-5p",-0.32,-0.44,0.99,"2005, 2007, 2009, 2011\n"]
["let-7a/let-7c","let-7-5p/98-5p","USP44","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000552440.1","ubiquitin specific peptidase 44 ",29,3,0,0,3,0,0,0,0,2,"hsa-let-7d-5p",-1.01,-1.3,"> 0.99","2009, 2011\n"]
["mir-26a","miR-26-5p  ","USP9X","+","no data","no data","+","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000324545.8","ubiquitin specific peptidase 9, X-linked ",2433,2,1,0,1,1,0,1,0,1,"hsa-miR-26a-5p",-0.03,-0.33,0.94,"2007, 2009, 2011\n"]
["mir-17","miR-17-5p/20-5p/93-5p/106-5p/519-3p","VANGL1","no data","no data","+","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000355485.2","VANGL planar cell polarity protein 1 ",721,2,1,1,0,0,0,0,0,2,"hsa-miR-17-5p",-0.32,-0.38,0.97,"2005, 2007, 2009, 2011\n"]
["let-7a/let-7c","let-7-5p/98-5p","VANGL2","+","no data","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000368061.2","VANGL planar cell polarity protein 2 ",560,2,0,1,1,0,0,0,0,0,"hsa-let-7b-5p",-0.37,-0.37,0.99,"2007, 2009, 2011\n"]
["mir-29b","miR-29-3p ","VASH1","+","+","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000167106.4","vasohibin 1 ",39,2,1,1,0,0,0,0,0,0,"hsa-miR-29a-3p",-0.49,-0.49,0.9,"2009, 2011\n"]
["mir-23b","miR-23-3p      ","VCAN","no data","no data","no data","no data","no data","no data","no data","no data","+","+","+","no data","ENST00000265077.3","versican ",542,2,1,1,0,1,0,1,0,0,"hsa-miR-23a-3p",-0.03,-0.2,0.74,2011]
["let-7a/let-7c","let-7-5p/98-5p","VSTM5","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000409977.1","V-set and transmembrane domain containing 5 ",5,2,2,0,0,0,0,0,0,0,"hsa-let-7d-5p",-0.95,-0.95,"> 0.99","\n"]
["mir-26a","miR-26-5p  ","WAPAL","+","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000298767.5","wings apart-like homolog (Drosophila) ",185,2,0,1,1,0,0,0,0,0,"hsa-miR-26a-5p",-0.15,-0.18,0.76,"2007, 2009, 2011\n"]
["mir-148a","miR-148-3p/152-3p","WDR47","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000400794.3","WD repeat domain 47 ",185,2,0,2,0,0,0,0,0,0,"hsa-miR-152-3p",-0.59,-0.59,0.66,"2009, 2011\n"]
["mir-23b","miR-23-3p      ","WISP1","no data",null,"+","no data","no data","no data","no data","no data","no data","no data","no data","+","ENST00000517423.1","WNT1 inducible signaling pathway protein 1 ",5,2,2,0,0,0,0,0,0,0,"hsa-miR-23a-3p",0,-0.26,0.22,2011]
["mir-23b","miR-23-3p      ","XIAP","+","+","+","+","no data","no data","no data","no data","no data","no data","no data","+","ENST00000371199.3","X-linked inhibitor of apoptosis ",153,4,2,1,1,1,0,0,1,2,"hsa-miR-23b-3p",-0.21,-0.28,0.77,2011]
["let-7a/let-7c","let-7-5p/98-5p","XKR4","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","ENST00000327381.6","XK, Kell blood group complex subunit-related family, member 4 ",5,2,2,0,0,0,0,0,0,2,"hsa-let-7d-5p",-0.33,-0.33,"> 0.99","\n"]
["mir-29b","miR-29-3p ","XKR4","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","ENST00000327381.6","XK, Kell blood group complex subunit-related family, member 4 ",5,2,0,1,1,0,0,0,0,0,"hsa-miR-29a-3p",-0.29,-0.29,0.99,"2007, 2009, 2011\n"]
["mir-29b","miR-29-3p ","XKR6","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","+","ENST00000304437.2","XK, Kell blood group complex subunit-related family, member 6 ",5,2,0,2,0,0,0,0,0,1,"hsa-miR-29b-3p",-0.91,-0.91,0.97,"2003, 2007, 2009, 2011\n"]
["miR-101","miR-101-3p.1  ","XYLT1","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","+","no data","ENST00000261381.6","xylosyltransferase I ",159,2,0,0,2,0,0,0,0,1,"hsa-miR-101-3p.1",-0.05,-0.05,0.68,"2007, 2009, 2011\n"]
["let-7a/let-7c","let-7-5p/98-5p","ZBTB16","no data","+","no data","no data","no data","no data","no data","no data","+","+","+","no data","ENST00000335953.4","zinc finger and BTB domain containing 16 ",73,3,1,1,1,0,0,0,0,2,"hsa-let-7g-5p",-0.72,-0.79,"> 0.99"]
["mir-218","miR-218-5p","ZBTB16","no data","+","no data","no data","no data","no data","no data","+","+","+","no data","no data","ENST00000335953.4","zinc finger and BTB domain containing 16 ",73,2,0,1,1,0,0,0,0,2,"hsa-miR-218-5p",-0.15,-0.16,0.95,"\n"]
["mir-23b","miR-23-3p      ","ZBTB16","no data","-","no data","no data","no data","no data","no data","+","+","+","no data",null,"ENST00000335953.4","zinc finger and BTB domain containing 16 ",73,2,2,0,0,2,0,1,1,1,"hsa-miR-23c",-0.11,-0.11,0.86,"\n"]
["mir-26a","miR-26-5p  ","ZBTB16","no data","-","no data","no data","no data","no data",null,"+","+","+","no data",null,"ENST00000335953.4","zinc finger and BTB domain containing 16 ",73,2,1,0,1,0,0,0,0,0,"hsa-miR-26a-5p",-0.11,-0.12,0.98,"\n"]
["miR-101","miR-101-3p.1  ","ZBTB18","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000358704.4","zinc finger and BTB domain containing 18 ",935,2,0,0,2,0,0,0,0,1,"hsa-miR-101-3p.1",-0.16,-0.16,0.58,"2007, 2009, 2011\n"]
["miR-125-5p","miR-125-5p","ZBTB7A","no data","no data","no data","no data","no data","no data","no data","+","+","no data","+","+","ENST00000322357.4","zinc finger and BTB domain containing 7A ",37,2,1,1,0,2,0,2,0,1,"hsa-miR-125b-5p",-0.23,-0.24,0.99,"2007, 2009, 2011\n"]
["mir-17","miR-17-5p/20-5p/93-5p/106-5p/519-3p","ZBTB7A","no data","no data","no data","no data","no data","no data","no data","+","+","no data","+","+","ENST00000322357.4","zinc finger and BTB domain containing 7A ",37,4,0,3,1,0,0,0,0,1,"hsa-miR-519d-3p",-0.75,-0.84,0.99,"2007, 2009, 2011\n"]
["miR-101","miR-101-3p.1  ","ZEB1","no data","+","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000361642.5","zinc finger E-box binding homeobox 1 ",59,2,1,0,1,0,0,0,0,1,"hsa-miR-101-3p.1",-0.23,-0.23,0.85,2011]
["miR-101","miR-101-3p.1  ","ZFP36L2","+","+","no data","no data","no data","no data","+","no data","+","no data","+","no data","ENST00000282388.3","ZFP36 ring finger protein-like 2 ",317,2,1,0,1,1,0,1,0,1,"hsa-miR-101-3p.1",-0.32,-0.54,0.9,2011]
["mir-22","miR-22-3p   ","ZFP36L2","+","+","no data","no data","no data","no data","+","no data","+","no data","+","no data","ENST00000282388.3","ZFP36 ring finger protein-like 2 ",317,2,0,1,1,0,0,0,0,1,"hsa-miR-22-3p",-0.15,-0.23,0.79,"2005, 2007\n"]
["miR-222","miR-221-3p/222-3p     ","ZFPM2","no data","+","no data","no data","no data","no data","no data","no data","+","no data","+","+","ENST00000407775.2","zinc finger protein, FOG family member 2 ",595,2,0,1,1,0,0,0,0,0,"hsa-miR-221-3p",-0.33,-0.33,0.54,"2005, 2007, 2009, 2011\n"]
["mir-17","miR-17-5p/20-5p/93-5p/106-5p/519-3p","ZFYVE26","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000347230.4","zinc finger, FYVE domain containing 26 ",104,2,2,0,0,0,0,0,0,0,"hsa-miR-519d-3p",-0.2,-0.45,"> 0.99","2005, 2007, 2009, 2011\n"]
["mir-26a","miR-26-5p  ","ZIC5","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","+","no data","ENST00000267294.4","Zic family member 5 ",263,2,1,0,1,0,0,0,0,0,"hsa-miR-26a-5p",-0.38,-0.41,0.94,"2007, 2009, 2011\n"]
["miR-101","miR-101-3p.1  ","ZNF207","+","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","ENST00000394670.4","zinc finger protein 207 ",839,2,0,1,1,4,0,1,3,2,"hsa-miR-101-3p.1",-0.5,-0.57,"> 0.99","2005, 2007, 2009, 2011\n"]
["miR-138","miR-138-5p","ZNF74","no data","no data","no data","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000357502.5","zinc finger protein 74 ",142,2,0,2,0,1,0,1,0,4,"hsa-miR-138-5p",-0.34,-0.49,"< 0.1","\n"]
["miR-125-5p","miR-125-5p","ZNRF3","no data","+","+","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000544604.2","zinc and ring finger 3 ",179,2,0,1,1,0,0,0,0,1,"hsa-miR-125a-5p",-0.36,-0.44,0.97,"2009, 2011\n"]
["mir-146b-5p","mir-146b-5p","ZNRF3","no data","+","+","no data","no data","no data","no data","no data","no data","no data","+","no data","ENST00000544604.2","zinc and ring finger 3 ",179,2,0,1,1,0,0,0,0,2,"hsa-miR-146b-5p",-0.2,-0.23,0.2,"2009, 2011\n"]

{"sheet":"let-7a","index":2,"n_rows":18,"n_cols":19,"rows_kept":18,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["Altered MicroRNA Expression Profile in Exosomes during Osteogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells","BMSCs","bone marrow",null,"exosomes during osteogenic differentiation","let-7a","2.239",{"$nulls":4},"microarrays"]
["Altered MicroRNA Expression Profile in Exosomes during Osteogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells","BMSCs","bone marrow",null,"exosomes during osteogenic differentiation 0,5 day","let-7a",1.6,{"$nulls":4},"RT-qPCR",null,"mean±SEM"]
["Altered MicroRNA Expression Profile in Exosomes during Osteogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells","BMSCs","bone marrow",null,"exosomes during osteogenic differentiation 1 day","let-7a",2.4,{"$nulls":4},"RT-qPCR",null,"mean±SEM"]
["Altered MicroRNA Expression Profile in Exosomes during Osteogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells","BMSCs","bone marrow",null,"exosomes during osteogenic differentiation 1,5 day","let-7a",1.75,{"$nulls":4},"RT-qPCR",null,"mean±SEM"]
["Altered MicroRNA Expression Profile in Exosomes during Osteogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells","BMSCs","bone marrow",null,"exosomes during osteogenic differentiation 2 day","let-7a",1.75,{"$nulls":4},"RT-qPCR",null,"mean±SEM"]
["Altered MicroRNA Expression Profile in Exosomes during Osteogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells","BMSCs","bone marrow",null,"exosomes during osteogenic differentiation 2,5 day","let-7a",2.1,{"$nulls":4},"RT-qPCR",null,"mean±SEM"]
["Altered MicroRNA Expression Profile in Exosomes during Osteogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells","BMSCs","bone marrow",null,"exosomes during osteogenic differentiation 3 day","let-7a",1.45,{"$nulls":4},"RT-qPCR",null,"mean±SEM"]
["Altered MicroRNA Expression Profile in Exosomes during Osteogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells","BMSCs","bone marrow",null,"exosomes during osteogenic differentiation 4 day","let-7a",1.45,{"$nulls":4},"RT-qPCR",null,"mean±SEM"]
["Altered MicroRNA Expression Profile in Exosomes during Osteogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells","BMSCs","bone marrow",null,"exosomes during osteogenic differentiation 5 day","let-7a",3,{"$nulls":4},"RT-qPCR",null,"mean±SEM"]
["Altered MicroRNA Expression Profile in Exosomes during Osteogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells","BMSCs","bone marrow",null,"exosomes during osteogenic differentiation 7 day","let-7a",1.2,{"$nulls":4},"RT-qPCR",null,"mean±SEM"]
["The effects of hedgehog on RNA binding protein Msi1 during the osteogenic differentiation of human cord blood-derived mesenchymal stem cells","hUCB-MSCs","umbilical cord blood",null,"osteogenic differentiation 21 day ","let-7a",1.1,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]
["The effects of hedgehog on RNA binding protein Msi1 during the osteogenic differentiation of human cord blood-derived mesenchymal stem cells","hUCB-MSCs","umbilical cord blood",null,"osteogenic differentiation 21 day + purmorphamine (activates the Hh pathway)","let-7a",1.2,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]
["miR‑214 promotes periodontal ligament stem cell osteoblastic differentiation by modulating Wnt/β‑catenin signaling","PDLSCs","human premolars","5 men aged 18-24 years","osteogenic differentiation","let-7a",5.5,{"$nulls":4},"RT-qPCR",null,"mean ± SD, unpaired two-tailed t-test"]
["Differentiating Human Multipotent Mesenchymal Stromal Cells Regulate microRNAs: Prediction of microRNA Regulation by PDGF During Osteogenesis","MSC",null,"1678C (18y, African American, male), 1822A (22y, African American, male), 1832A (18y, African American, male), and 1271C (23y, African American, Female), and were designated as Donors 1, 2, 3, and 4, respectively","osteogenic differentiation 7 day","let-7a",3,{"$nulls":4},"RT-qPCR",null,"mean±SEM, Student t test"]
["Differentiating Human Multipotent Mesenchymal Stromal Cells Regulate microRNAs: Prediction of microRNA Regulation by PDGF During Osteogenesis","MSC",null,"1678C (18y, African American, male), 1822A (22y, African American, male), 1832A (18y, African American, male), and 1271C (23y, African American, Female), and were designated as Donors 1, 2, 3, and 4, respectively","osteogenic differentiation 7 day","let-7a",1.75,{"$nulls":4},"RT-qPCR",null,"mean±SEM, Student t test"]
["Differentiating Human Multipotent Mesenchymal Stromal Cells Regulate microRNAs: Prediction of microRNA Regulation by PDGF During Osteogenesis","pooled MSC",null,"1678C (18y, African American, male), 1822A (22y, African American, male), 1832A (18y, African American, male), and 1271C (23y, African American, Female), and were designated as Donors 1, 2, 3, and 4, respectively","treated with the PDGF pathway inhibitor AG-370 during differentiation","let-7a",4,{"$nulls":4},"RT-qPCR",null,"mean±SEM, Student t test"]
["Differentiating Human Multipotent Mesenchymal Stromal Cells Regulate microRNAs: Prediction of microRNA Regulation by PDGF During Osteogenesis","pooled MSC",null,"1678C (18y, African American, male), 1822A (22y, African American, male), 1832A (18y, African American, male), and 1271C (23y, African American, Female), and were designated as Donors 1, 2, 3, and 4, respectively","treated with the PDGF pathway inhibitor AG-370 during differentiation","let-7a",1,{"$nulls":4},"RT-qPCR",null,"mean±SEM, Student t test"]

{"sheet":"let-7b","index":3,"n_rows":7,"n_cols":19,"rows_kept":7,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["The effects of hedgehog on RNA binding protein Msi1 during the osteogenic differentiation of human cord blood-derived mesenchymal stem cells","hUCB-MSCs","umbilical cord blood",null,"osteogenic differentiation 21 day ","let-7b",1.6,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]
["The effects of hedgehog on RNA binding protein Msi1 during the osteogenic differentiation of human cord blood-derived mesenchymal stem cells","hUCB-MSCs","umbilical cord blood",null,"osteogenic differentiation 21 day + purmorphamine (activates the Hh pathway)","let-7b",1.2,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]
["Differentiating Human Multipotent Mesenchymal Stromal Cells Regulate microRNAs: Prediction of microRNA Regulation by PDGF During Osteogenesis","MSC",null,"1678C (18y, African American, male), 1822A (22y, African American, male), 1832A (18y, African American, male), and 1271C (23y, African American, Female), and were designated as Donors 1, 2, 3, and 4, respectively","osteogenic differentiation 7 day","let-7b",2.5,{"$nulls":4},"RT-qPCR",null,"mean±SEM, Student t test"]
["Differentiating Human Multipotent Mesenchymal Stromal Cells Regulate microRNAs: Prediction of microRNA Regulation by PDGF During Osteogenesis","MSC",null,"1678C (18y, African American, male), 1822A (22y, African American, male), 1832A (18y, African American, male), and 1271C (23y, African American, Female), and were designated as Donors 1, 2, 3, and 4, respectively","osteogenic differentiation 7 day","let-7b",1.75,{"$nulls":4},"RT-qPCR",null,"mean±SEM, Student t test"]
["Differentiating Human Multipotent Mesenchymal Stromal Cells Regulate microRNAs: Prediction of microRNA Regulation by PDGF During Osteogenesis","pooled MSC",null,"1678C (18y, African American, male), 1822A (22y, African American, male), 1832A (18y, African American, male), and 1271C (23y, African American, Female), and were designated as Donors 1, 2, 3, and 4, respectively","treated with the PDGF pathway inhibitor AG-370 during differentiation","let-7b",2.6,{"$nulls":4},"RT-qPCR",null,"mean±SEM, Student t test"]
["Differentiating Human Multipotent Mesenchymal Stromal Cells Regulate microRNAs: Prediction of microRNA Regulation by PDGF During Osteogenesis","pooled MSC",null,"1678C (18y, African American, male), 1822A (22y, African American, male), 1832A (18y, African American, male), and 1271C (23y, African American, Female), and were designated as Donors 1, 2, 3, and 4, respectively","treated with the PDGF pathway inhibitor AG-370 during differentiation","let-7b",1,{"$nulls":4},"RT-qPCR",null,"mean±SEM, Student t test"]

{"sheet":"le7-7c","index":4,"n_rows":11,"n_cols":19,"rows_kept":11,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["Hsa-let-7c controls the committed differentiation of IGF-1-treated mesenchymal stem cells derived from dental pulps by targeting IGF-1R via the MAPK pathways","DPMSCs","third molars",null,"overexpression of miR; 100 ng/mL IGF-1 treatment","let-7c",{"$nulls":8},"ERK, JNK,  p38 downregulated","down"]
["miR-216a rescues dexamethasone suppression of osteogenesis , promotes osteoblast differentiation and enhances bone formation , by regulating c-Cbl-mediated PI3K / AKT pathway","hAMSCs","adipose tissue","healthy donors","osteogenic differentiation 4 day 1 sample","let-7c",37.98856998196172,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]
["miR-216a rescues dexamethasone suppression of osteogenesis , promotes osteoblast differentiation and enhances bone formation , by regulating c-Cbl-mediated PI3K / AKT pathway","hAMSCs","adipose tissue","healthy donors","osteogenic differentiation 4 day 2 sample","let-7c",34.938033431975725,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]
["miR-216a rescues dexamethasone suppression of osteogenesis , promotes osteoblast differentiation and enhances bone formation , by regulating c-Cbl-mediated PI3K / AKT pathway","hAMSCs","adipose tissue","healthy donors","osteogenic differentiation 4 day 3 sample","let-7c",16.742679148326918,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]
["The effects of hedgehog on RNA binding protein Msi1 during the osteogenic differentiation of human cord blood-derived mesenchymal stem cells","hUCB-MSCs","umbilical cord blood",null,"osteogenic differentiation 21 day ","let-7c",1.1,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]
["The effects of hedgehog on RNA binding protein Msi1 during the osteogenic differentiation of human cord blood-derived mesenchymal stem cells","hUCB-MSCs","umbilical cord blood",null,"osteogenic differentiation 21 day + purmorphamine (activates the Hh pathway)","let-7c",1.1,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]
["Differentiating Human Multipotent Mesenchymal Stromal Cells Regulate microRNAs: Prediction of microRNA Regulation by PDGF During Osteogenesis","MSC","MSC","1678C (18y, African American, male), 1822A (22y, African American, male), 1832A (18y, African American, male), and 1271C (23y, African American, Female), and were designated as Donors 1, 2, 3, and 4, respectively","osteogenic differentiation 7 day","let-7c",2,{"$nulls":4},"RT-qPCR",null,"mean±SEM, Student t test"]
["Differentiating Human Multipotent Mesenchymal Stromal Cells Regulate microRNAs: Prediction of microRNA Regulation by PDGF During Osteogenesis","MSC","MSC","1678C (18y, African American, male), 1822A (22y, African American, male), 1832A (18y, African American, male), and 1271C (23y, African American, Female), and were designated as Donors 1, 2, 3, and 4, respectively","osteogenic differentiation 7 day","let-7c",1.75,{"$nulls":4},"RT-qPCR",null,"mean±SEM, Student t test"]
["Differentiating Human Multipotent Mesenchymal Stromal Cells Regulate microRNAs: Prediction of microRNA Regulation by PDGF During Osteogenesis","pooled MSC","pooled MSC","1678C (18y, African American, male), 1822A (22y, African American, male), 1832A (18y, African American, male), and 1271C (23y, African American, Female), and were designated as Donors 1, 2, 3, and 4, respectively","treated with the PDGF pathway inhibitor AG-370 during differentiation","let-7c",3,{"$nulls":4},"RT-qPCR",null,"mean±SEM, Student t test"]
["Differentiating Human Multipotent Mesenchymal Stromal Cells Regulate microRNAs: Prediction of microRNA Regulation by PDGF During Osteogenesis","pooled MSC","pooled MSC","1678C (18y, African American, male), 1822A (22y, African American, male), 1832A (18y, African American, male), and 1271C (23y, African American, Female), and were designated as Donors 1, 2, 3, and 4, respectively","treated with the PDGF pathway inhibitor AG-370 during differentiation","let-7c",1.25,{"$nulls":4},"RT-qPCR",null,"mean±SEM, Student t test"]

{"sheet":"mir-100","index":5,"n_rows":9,"n_cols":19,"rows_kept":9,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["Altered function in cartilage derived mesenchymal stem cell leads to OA-related cartilage erosion","CMSC","medial and lateral condyles","12 patients (4 males, 8 females, median age 67.8 years, range 47-79 years)","osteoarthritis","miR-100",null,"1.098098 ",{"$nulls":3},"microarrays"]
["Altered function in cartilage derived mesenchymal stem cell leads to OA-related cartilage erosion","CMSC","medial and lateral condyles","12 patients (4 males, 8 females, median age 67.8 years, range 47-79 years)","osteoarthritis","miR-100",1,{"$nulls":4},"RT-qPCR",null,"mean+SEM"]
["Altered function in cartilage derived mesenchymal stem cell leads to OA-related cartilage erosion","CMSC","medial and lateral condyles","12 patients (4 males, 8 females, median age 67.8 years, range 47-79 years)","osteoarthritis","miR-100",0.9,{"$nulls":4},"RT-qPCR",null,"mean+SEM"]
["MicroRNA expression pro fi ling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-55","MSCs","bone marrow","3 donors","full confluence of the culture after the addition of the differentiating medium vs control","miR-100",null,"0.782408  ",{"$nulls":3},"microarrays"]
["MicroRNA expression pro fi ling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-56","MSCs","bone marrow","3 donors","full confluence of the culture after the addition of the differentiating medium vs control","miR-100",null,"1.39608",{"$nulls":3},"microarrays"]
["MicroRNA expression pro fi ling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-57","MSCs","bone marrow","3 donors","full confluence of the culture after the addition of the differentiating medium vs control","miR-100",null,"1.41878",{"$nulls":3},"microarrays"]
["miR‑214 promotes periodontal ligament stem cell osteoblastic differentiation by modulating Wnt/β‑catenin signaling","PDLSCs","human premolars","5 men aged 18-24 years","osteogenic differentiation","miR-100 ",5,{"$nulls":4},"RT-qPCR",null,"mean ± SD, unpaired two-tailed t-test"]
["MicroRNA-138 regulates osteogenic differentiation of human stromal (mesenchymal) stem cells in vivo","hMSCs","telomerase immortalized bone marrow",null,"osteogenic differentiation 10 day","miR-100 ",null,"−0.01 ± 0.19 ",{"$nulls":3},"microarrays",null,"mean ± SD"]

{"sheet":"mir-101","index":6,"n_rows":9,"n_cols":19,"rows_kept":9,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["MiR-101 Targets the EZH2/Wnt/β- Catenin the Pathway to Promote the Osteogenic Differentiation of Human Bone Marrow-Derived","hBMSCs",null,null,"1 day after osteogenic stimuli","miR-101",2.5,{"$nulls":4},"RT-qPCR","up","mean ± SD","EZH2 (3′ -UTRs (114–121))"]
["MiR-101 Targets the EZH2/Wnt/β- Catenin the Pathway to Promote the Osteogenic Differentiation of Human Bone Marrow-Derived","hBMSCs",null,null,"5 day after osteogenic stimuli","miR-101",5,{"$nulls":4},"RT-qPCR","up","mean ± SD"]
["MiR-101 Targets the EZH2/Wnt/β- Catenin the Pathway to Promote the Osteogenic Differentiation of Human Bone Marrow-Derived","hBMSCs",null,null,"10 day after osteogenic stimuli","miR-101",7,{"$nulls":4},"RT-qPCR","up","mean ± SD"]
["MiR-101 Targets the EZH2/Wnt/β- Catenin the Pathway to Promote the Osteogenic Differentiation of Human Bone Marrow-Derived","hBMSCs",null,null,"15 day after osteogenic stimuli","miR-101",9,{"$nulls":4},"RT-qPCR","up","mean ± SD"]
["MicroRNAs miR-26a, miR-26b, and miR-29b accelerate osteogenic differentiation of unrestricted somatic stem cells from human cord blood","SA5/73","USSC, human cord blood",null,"7 day after osteogenic stimuli","miR-101",4,{"$nulls":4},"microarrays"]
["MicroRNAs miR-26a, miR-26b, and miR-29b accelerate osteogenic differentiation of unrestricted somatic stem cells from human cord blood","SA8/25","USSC, human cord blood",null,"7 day after osteogenic stimuli","miR-101",11,{"$nulls":4},"microarrays"]
["MicroRNA-138 regulates osteogenic differentiation of human stromal (mesenchymal) stem cells in vivo","hMSCs","telomerase immortalized bone marrow",null,"osteogenic differentiation 10 day","miR-101",6.14750072515205,2.62,{"$nulls":3},"RT-qPCR",null,"mean ± SD"]
["MicroRNA-138 regulates osteogenic differentiation of human stromal (mesenchymal) stem cells in vivo","hMSCs","telomerase immortalized bone marrow",null,"osteogenic differentiation 10 day","miR-101 ",1.9453098948245708,0.96,{"$nulls":3},"microarrays",null,"mean ± SD"]

{"sheet":"mir-106b","index":7,"n_rows":5,"n_cols":19,"rows_kept":5,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["MiR-708 promotes steroid- induced osteonecrosis of femoral head , suppresses osteogenic differentiation by targeting SMAD3","hMSCs","bone marrow","patients with GC-ONFH (n = 13)","glucocorticoid treatment (steroid-induced osteonecrosis of femoral head model)","miR-106b",0.5,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]
["MiR-708 promotes steroid- induced osteonecrosis of femoral head , suppresses osteogenic differentiation by targeting SMAD3","hMSCs","bone marrow","patients with GC-ONFH (n = 13)","dexamethazone 10-8 M + glucocorticoid treatment (steroid-induced osteonecrosis of femoral head model)","miR-106b",2.5,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]
["MiR-708 promotes steroid- induced osteonecrosis of femoral head , suppresses osteogenic differentiation by targeting SMAD3","hMSCs","bone marrow","patients with GC-ONFH (n = 13)","dexamethazone 10-7 M + glucocorticoid treatment (steroid-induced osteonecrosis of femoral head model)","miR-106b",3.75,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]
["MiR-708 promotes steroid- induced osteonecrosis of femoral head , suppresses osteogenic differentiation by targeting SMAD3","hMSCs","bone marrow","patients with GC-ONFH (n = 13)","dexamethazone 10-6 M + glucocorticoid treatment (steroid-induced osteonecrosis of femoral head model)","miR-106b",3.75,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]

{"sheet":"mir-10a-5p","index":8,"n_rows":4,"n_cols":19,"rows_kept":4,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["The microRNA-10a / ID3 / RUNX2 axis modulates the development of Ossification of Posterior Longitudinal Ligament",null,"posterior longitudinal ligament (OPLL)",11,"Ossification of the posterior longitudinal ligamen","miR-10a-5p",25,{"$nulls":4},"RT-qPCR",null,"mean ± SD",null,"up"]
["The microRNA-10a / ID3 / RUNX2 axis modulates the development of Ossification of Posterior Longitudinal Ligament",null,"posterior longitudinal ligament",9,"None ossified normal longitudinal ligament","miR-10a-5p",2,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]
["Modulation of Micro RNA Expression and Osteoblast Differentiation by Nanotopography","hMSCs",null,null,"mechanical induction of osteogenesis 14 day","miR-10a-5p","1.578",{"$nulls":4},"RNA-Seq",null,"t test"]

{"sheet":"mir-15b","index":9,"n_rows":6,"n_cols":19,"rows_kept":6,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["A Positive Role of microRNA-15b on Regulation of Osteoblast Differentiation","hMSCs","bone marrow","27 years old female","osteogenic differentiation 0 day","miR-15b",1,{"$nulls":4},"RT-qPCR",null,"mean ± SD, ANOVA analysis","Smurf1 decrease"]
["A Positive Role of microRNA-15b on Regulation of Osteoblast Differentiation","hMSCs","bone marrow","27 years old female","osteogenic differentiation 7 day","miR-15b",1.5,{"$nulls":4},"RT-qPCR",null,"mean ± SD, ANOVA analysis","Smurf1 decrease"]
["A Positive Role of microRNA-15b on Regulation of Osteoblast Differentiation","hMSCs","bone marrow","27 years old female","osteogenic differentiation 14 day","miR-15b",3,{"$nulls":4},"RT-qPCR",null,"mean ± SD, ANOVA analysis","Smurf1 decrease"]
["A Positive Role of microRNA-15b on Regulation of Osteoblast Differentiation","MG63","Human osteoblast cells",null,"differentiated","miR-15b",3.25,{"$nulls":4},"RT-qPCR",null,"mean ± SD, ANOVA analysis","Smurf1 decrease"]
["MiR-590-3p regulates osteogenic differentiation of human mesenchymal stem cells by regulating APC gene","HMSCs",null,null,"osteogenic differentiation 25 day","miR-15b",2.7,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]

{"sheet":"mir-16-5p","index":10,"n_rows":4,"n_cols":19,"rows_kept":4,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["MiRNA expression in the cartilage of patients with osteoarthritis",null,"femoral heads","29 OA patients","osteoarthritis","miR-16-5p",1.1,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]
["Osteogenic Differentiation of MSC through Calcium Signaling Activation : Transcriptomics and Functional Analysis","hMSCs","bone marrow",null,"calcium-based scaffolds induced osteogenic differentiation 5 day vs 0 day","miR-16-5p",null,"1.07196188031211",{"$nulls":3},"microarrays",null,"mean±SEM"]
["Pathogenesis of glucocorticoid-induced avascular necrosis : A microarray analysis of gene expression in vitro","BMSCs","bone marrow",null,"treatment with 10-9 and 10-7 mol/l dexamethasone","miR‑16‑5p",{"$nulls":3},"up"]

{"sheet":"mir-17","index":11,"n_rows":24,"n_cols":19,"rows_kept":24,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["Osteogenic Differentiation of Human Amniotic Fluid Mesenchymal Stem Cells Is Determined by Epigenetic Changes","AF-MSCs","amniotic fluid","second trimester, healthy women","osteogenic differentiation 5 day","miR-17",0.75,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]
["Osteogenic Differentiation of Human Amniotic Fluid Mesenchymal Stem Cells Is Determined by Epigenetic Changes","AF-MSCs","amniotic fluid","second trimester, healthy women","osteogenic differentiation 9 day","miR-17",0.6,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]
["Osteogenic Differentiation of Human Amniotic Fluid Mesenchymal Stem Cells Is Determined by Epigenetic Changes","AF-MSCs","amniotic fluid","second trimester, healthy women","osteogenic differentiation 15 day","miR-17",0.65,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]
["MiR-17 Modulates Osteogenic Differentiation Through a Coherent Feed-Forward Loop in Mesenchymal Stem Cells Isolated from Periodontal Ligaments of Patients with Periodontitis","PDLSCs","tooth samples","8 individuals, aged 29–38 years","osteogenic differentiation 3 day","miR-17",0.85,{"$nulls":4},"RT-qPCR",null,"mean ± SD, two-tailed Student t test",null,"down"]
["MiR-17 Modulates Osteogenic Differentiation Through a Coherent Feed-Forward Loop in Mesenchymal Stem Cells Isolated from Periodontal Ligaments of Patients with Periodontitis","PDLSCs","tooth samples","8 individuals, aged 29–38 years","osteogenic differentiation 7 day","miR-17",0.35,{"$nulls":4},"RT-qPCR",null,"mean ± SD, two-tailed Student t test",null,"down"]
["MiR-17 Modulates Osteogenic Differentiation Through a Coherent Feed-Forward Loop in Mesenchymal Stem Cells Isolated from Periodontal Ligaments of Patients with Periodontitis","PDLSCs","tooth samples","8 individuals, aged 29–38 years","osteogenic differentiation 14 day","miR-17",0.5,{"$nulls":4},"RT-qPCR",null,"mean ± SD, two-tailed Student t test",null,"down"]
["MiR-17 Modulates Osteogenic Differentiation Through a Coherent Feed-Forward Loop in Mesenchymal Stem Cells Isolated from Periodontal Ligaments of Patients with Periodontitis","PDLSCs","tooth samples","7 periodontic clinic patients (31– 42 years of age) diagnosed with chronic periodontitis","osteogenic differentiation 0 day","miR-17",0.9,{"$nulls":4},"RT-qPCR",null,"mean ± SD, two-tailed Student t test",null,"up"]
["MiR-17 Modulates Osteogenic Differentiation Through a Coherent Feed-Forward Loop in Mesenchymal Stem Cells Isolated from Periodontal Ligaments of Patients with Periodontitis","PDLSCs","tooth samples","7 periodontic clinic patients (31– 42 years of age) diagnosed with chronic periodontitis","osteogenic differentiation 3 day","miR-17",0.72,{"$nulls":4},"RT-qPCR",null,"mean ± SD, two-tailed Student t test",null,"up"]
["MiR-17 Modulates Osteogenic Differentiation Through a Coherent Feed-Forward Loop in Mesenchymal Stem Cells Isolated from Periodontal Ligaments of Patients with Periodontitis","PDLSCs","tooth samples","7 periodontic clinic patients (31– 42 years of age) diagnosed with chronic periodontitis","osteogenic differentiation 7 day","miR-17",0.25,{"$nulls":4},"RT-qPCR",null,"mean ± SD, two-tailed Student t test",null,"up"]
["MiR-17 Modulates Osteogenic Differentiation Through a Coherent Feed-Forward Loop in Mesenchymal Stem Cells Isolated from Periodontal Ligaments of Patients with Periodontitis","PDLSCs","tooth samples","7 periodontic clinic patients (31– 42 years of age) diagnosed with chronic periodontitis","osteogenic differentiation 14 day","miR-17",0.3,{"$nulls":4},"RT-qPCR",null,"mean ± SD, two-tailed Student t test",null,"up"]
["MiR-17 Modulates Osteogenic Differentiation Through a Coherent Feed-Forward Loop in Mesenchymal Stem Cells Isolated from Periodontal Ligaments of Patients with Periodontitis","PDLSCs","tooth samples","8 individuals, aged 29–38 years","osteogenic differentiation + IL-1β (1 ng/ ml)","miR-17",0.6,{"$nulls":4},"RT-qPCR",null,"mean ± SD, two-tailed Student t test"]
["MiR-17 Modulates Osteogenic Differentiation Through a Coherent Feed-Forward Loop in Mesenchymal Stem Cells Isolated from Periodontal Ligaments of Patients with Periodontitis","PDLSCs","tooth samples","8 individuals, aged 29–38 years","osteogenic differentiation + TNF-α (10 ng/mL)","miR-17",0.65,{"$nulls":4},"RT-qPCR",null,"mean ± SD, two-tailed Student t test"]
["TCF3 , a novel positive regulator of osteogenesis , plays a crucial role in miR-17 modulating the diverse effect of canonical Wnt signaling in different microenvironments","PDLSCs",null,null,"osteogenic differentiation medium with Wnt3a","miR-17",1.4,{"$nulls":4},"RT-qPCR"]
["TCF3 , a novel positive regulator of osteogenesis , plays a crucial role in miR-17 modulating the diverse effect of canonical Wnt signaling in different microenvironments","PDLSCs",{"$nulls":3},"miR-17",{"$nulls":9},"down",null,null,"attenuate the effect of Wnt3a"]
["MicroRNA expression pro fi ling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-112","MSCs","bone marrow","3 donors","full confluence of the culture after the addition of the differentiating medium vs control","miR-17",null,"−0.400294  ",{"$nulls":3},"microarrays"]
["MicroRNA expression pro fi ling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-113","MSCs","bone marrow","3 donors","full confluence of the culture after the addition of the differentiating medium vs control","miR-17",null,"−0.640813",{"$nulls":3},"microarrays"]
["MicroRNA expression pro fi ling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-114","MSCs","bone marrow","3 donors","full confluence of the culture after the addition of the differentiating medium vs control","miR-17",null,"−0.820404",{"$nulls":3},"microarrays"]
["MicroRNA expression pro fi ling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-144","MSCs","bone marrow","3 donors","full confluence of the culture after the addition of the differentiating medium","miR-17",0.4,{"$nulls":4},"RT-qPCR",null,"mean+SEM"]
["MicroRNA expression pro fi ling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-143","MSCs","bone marrow","3 donors","control","miR-17",1.8,{"$nulls":4},"RT-qPCR",null,"mean+SEM"]
["MicroRNA expression pro fi ling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-145","MSCs","bone marrow","3 donors","mineral nodule deposition one week after the addition of the mineralization medium","miR-17",0.2,{"$nulls":4},"RT-qPCR",null,"mean+SEM"]
["MiR-17 Modulates Osteogenic Differentiation Through a Coherent Feed-Forward Loop in Mesenchymal Stem Cells Isolated from Periodontal Ligaments of Patients with Periodontitis","PDLSCs","tooth samples","8 individuals, aged 29–38 years","osteogenic differentiation 0 day","miR-17",1,{"$nulls":4},"RT-qPCR",null,"mean ± SD, two-tailed Student t test",null,"down"]
["Mutual inhibition between HDAC9 and miR-17 regulates osteogenesis of human periodontal ligament stem cells in inflammatory conditions","PDLSCs","tooth samples",null,"inflammation (TNFa induced)","miR-17",{"$nulls":12},"Inflammation impaired the osteogenesis capacity of PDLSCs"]
["lncRNA H19 mediates BMP9-induced osteogenic differentiation of mesenchymal stem cells (MSCs) through Notch signaling","iMADs","immortalized multipotent adipose-derived cells",null,"BMP9-induced osteogenic differentiation","miR-17",{"$nulls":3},"down",null,"RT-qPCR + clustering analysis"]

{"sheet":"mir-17-5p","index":12,"n_rows":14,"n_cols":20,"rows_kept":14,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["Long non-coding RNA HOTAIR inhibits MIR-17-5p to regulate osteogenic differentiation and proliferation in nontraumatic osteonecrosis of femoral head","BMSCs","bone marrow","patients with non-traumatic ONFH (n = 15)",null,"miR-17-5p",0.5,{"$nulls":4},"RT-qPCR",null,"mean±SEM, Student t test"]
["Long non-coding RNA HOTAIR inhibits MIR-17-5p to regulate osteogenic differentiation and proliferation in nontraumatic osteonecrosis of femoral head","BMSCs","bone marrow","patients with OA (n = 13)",null,"miR-17-5p",1,{"$nulls":4},"RT-qPCR",null,"mean±SEM, Student t test"]
["MiR-17-5p modulates osteoblastic differentiation and cell proliferation by targeting SMAD7 in non-traumatic osteonecrosis","hMSCs","bone marrow",null,"osteoarthritis","miR-17-5p",{"$nulls":5},"RT-qPCR",{"$nulls":7},-7]
["MiR-17-5p modulates osteoblastic differentiation and cell proliferation by targeting SMAD7 in non-traumatic osteonecrosis","hMSCs","bone marrow",null,"non-traumatic osteonecrosis","miR-17-5p",{"$nulls":5},"RT-qPCR",{"$nulls":7},-3.5]
["MiR-17-5p modulates osteoblastic differentiation and cell proliferation by targeting SMAD7 in non-traumatic osteonecrosis","hMSCs","bone marrow",null,"BMP-2 induced osteogenesis 1 day","miR-17-5p",1.5,{"$nulls":4},"RT-qPCR",null,"mean+SD, Mann–Whitney test","SMAD7 decrease","up"]
["MiR-17-5p modulates osteoblastic differentiation and cell proliferation by targeting SMAD7 in non-traumatic osteonecrosis","hMSCs","bone marrow",null,"BMP-2 induced osteogenesis 2 day","miR-17-5p",1.8,{"$nulls":4},"RT-qPCR",null,"mean+SD, Mann–Whitney test","SMAD7 decrease","up"]
["MiR-17-5p modulates osteoblastic differentiation and cell proliferation by targeting SMAD7 in non-traumatic osteonecrosis","hMSCs","bone marrow",null,"BMP-2 induced osteogenesis 4 day","miR-17-5p",1.4,{"$nulls":4},"RT-qPCR",null,"mean+SD, Mann–Whitney test","SMAD7 decrease","up"]
["MiR-17-5p modulates osteoblastic differentiation and cell proliferation by targeting SMAD7 in non-traumatic osteonecrosis","hMSCs","bone marrow",null,"BMP-2 induced osteogenesis 6 day","miR-17-5p",1,{"$nulls":4},"RT-qPCR",null,"mean+SD, Mann–Whitney test","SMAD7 decrease","up"]
["MiR-17-5p modulates osteoblastic differentiation and cell proliferation by targeting SMAD7 in non-traumatic osteonecrosis","hMSCs","bone marrow",null,"negative control 1 day","miR-17-5p",1.2,{"$nulls":4},"RT-qPCR",null,"mean+SD, Mann–Whitney test","SMAD7 decrease","up"]
["MiR-17-5p modulates osteoblastic differentiation and cell proliferation by targeting SMAD7 in non-traumatic osteonecrosis","hMSCs","bone marrow",null,"negative control 2 day","miR-17-5p",1,{"$nulls":4},"RT-qPCR",null,"mean+SD, Mann–Whitney test","SMAD7 decrease","up"]
["MiR-17-5p modulates osteoblastic differentiation and cell proliferation by targeting SMAD7 in non-traumatic osteonecrosis","hMSCs","bone marrow",null,"negative control 4 day","miR-17-5p",0.75,{"$nulls":4},"RT-qPCR",null,"mean+SD, Mann–Whitney test","SMAD7 decrease","up"]
["MiR-17-5p modulates osteoblastic differentiation and cell proliferation by targeting SMAD7 in non-traumatic osteonecrosis","hMSCs","bone marrow",null,"negative control 6 day","miR-17-5p",0.5,{"$nulls":4},"RT-qPCR",null,"mean+SD, Mann–Whitney test","SMAD7 decrease","up"]
["Long non-coding RNA HOTAIR inhibits MIR-17-5p to regulate osteogenic differentiation and proliferation in nontraumatic osteonecrosis of femoral head","BMSCs","bone marrow",null,null,"miR-17-5p",{"$nulls":9},"up",null,"down"]

{"sheet":"mir-18a","index":13,"n_rows":2,"n_cols":19,"rows_kept":2,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["MiR-1827 inhibits osteogenic differentiation by targeting IGF1 in MSMSCs","MSMSCs","maxillary sinus membrane stem cells","16 individuals aged 18–29 years ","osteogenic differentiation 3 day","miR-18a",1.05,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]

{"sheet":"mir-124","index":14,"n_rows":4,"n_cols":19,"rows_kept":4,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["MicroRNAs miR-96, miR-124, and miR-199a Regulate Gene Expression in Human Bone Marrow-Derived Mesenchymal Stem Cells","hMSCs","iliac bone","6 adult females (age 19–38 years)","control","miR-124","not detectable",{"$nulls":4},"RT-qPCR",null,"mean ± SD, Friedman test followed by the Wilcoxon test for paired comparisons"]
["MicroRNAs miR-96, miR-124, and miR-199a Regulate Gene Expression in Human Bone Marrow-Derived Mesenchymal Stem Cells","hMSCs","iliac bone","7 adult females (age 19–38 years)","osteogenic differentiation","miR-124","not detectable",{"$nulls":4},"RT-qPCR",null,"mean ± SD, Friedman test followed by the Wilcoxon test for paired comparisons"]
["MiR-1827 inhibits osteogenic differentiation by targeting IGF1 in MSMSCs","MSMSCs","maxillary sinus membrane stem cells","16 individuals aged 18–29 years ","osteogenic differentiation 3 day","miR-124",1,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]

{"sheet":"mir-125a-5p","index":15,"n_rows":2,"n_cols":19,"rows_kept":2,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["miR‑214 promotes periodontal ligament stem cell osteoblastic differentiation by modulating Wnt/β‑catenin signaling","PDLSCs","human premolars","5 men aged 18-24 years","osteogenic differentiation","miR-125a-5p",4,{"$nulls":4},"RT-qPCR",null,"mean ± SD, unpaired two-tailed t-test"]

{"sheet":"mir-125b","index":16,"n_rows":19,"n_cols":19,"rows_kept":19,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["Overexpression of hsa-miR-125b during osteoblastic differentiation does not influence levels of Runx2 , osteopontin , and ALPL gene expression","hBMSCs","bone marrow",null,"osteogenic differentiation 1 day","miR-125b",2,{"$nulls":4},"RT-qPCR",null,"Kruskal-Wallis test"]
["Overexpression of hsa-miR-125b during osteoblastic differentiation does not influence levels of Runx2 , osteopontin , and ALPL gene expression","hBMSCs","bone marrow",null,"osteogenic differentiation 3 day","miR-125b",2.5,{"$nulls":4},"RT-qPCR",null,"Kruskal-Wallis test"]
["Overexpression of hsa-miR-125b during osteoblastic differentiation does not influence levels of Runx2 , osteopontin , and ALPL gene expression","hBMSCs","bone marrow",null,"osteogenic differentiation 7 day","miR-125b",2,{"$nulls":4},"RT-qPCR",null,"Kruskal-Wallis test"]
["Overexpression of hsa-miR-125b during osteoblastic differentiation does not influence levels of Runx2 , osteopontin , and ALPL gene expression","hBMSCs","bone marrow",null,"osteogenic differentiation 14 day","miR-125b",2,{"$nulls":4},"RT-qPCR",null,"Kruskal-Wallis test"]
["Overexpression of hsa-miR-125b during osteoblastic differentiation does not influence levels of Runx2 , osteopontin , and ALPL gene expression","hBMSCs","bone marrow",null,"osteogenic differentiation 21 day","miR-125b",8,{"$nulls":4},"RT-qPCR",null,"Kruskal-Wallis test"]
["Global miRNA expression and correlation with mRNA levels in primary human bone cells","HOBs (primary human osteoblasts)","trabecular bone",null,"male","miR-125b",1,{"$nulls":4},"RT-qPCR",null,"Student’s t-test","FRZB, BGLAP decrease"]
["Global miRNA expression and correlation with mRNA levels in primary human bone cells","HOBs (primary human osteoblasts)","trabecular bone",null,"female","miR-125b",2,{"$nulls":4},"RT-qPCR",null,"Student’s t-test","FRZB, BGLAP decrease"]
["Adipogenic RNAs are transferred in osteoblasts via bone marrow adipocytes-derived extracellular vesicles ( EVs )","hMSC-Ost","purified",null,"14 days-differentiated osteoblasts incubated with conditioned medium from 14 days-differentiated adipocytes","miR-125b",0.48,{"$nulls":4},"RT-qPCR",null,"median of experimental data"]
["Biochemical and Biophysical Research Communications PDGF-regulated miRNA-138 inhibits the osteogenic differentiation of mesenchymal stem cells","hMSCs","Telomerase-immortalized bone marrow-derived",null,"osteogenesis + PDGF treatment 15 day","miR-125b",1.8,{"$nulls":4},"RT-qPCR",null,"mean+SEM"]
["miR-125b is an adhesion-regulated microRNA that protects mesenchymal stem cells from anoikis","hMSCs",null,null,"osteogenic differentiation (low density)","miR-125b",0.5,{"$nulls":4},"RT-qPCR",null,"nothing",null,"down"]
["Differentiating Human Multipotent Mesenchymal Stromal Cells Regulate microRNAs: Prediction of microRNA Regulation by PDGF During Osteogenesis","MSC",null,"1678C (18y, African American, male), 1822A (22y, African American, male), 1832A (18y, African American, male), and 1271C (23y, African American, Female), and were designated as Donors 1, 2, 3, and 4, respectively","osteogenic differentiation 7 day","miR-125b",2.5,{"$nulls":4},"RT-qPCR",null,"mean±SEM, Student t test"]
["Differentiating Human Multipotent Mesenchymal Stromal Cells Regulate microRNAs: Prediction of microRNA Regulation by PDGF During Osteogenesis","MSC",null,"1678C (18y, African American, male), 1822A (22y, African American, male), 1832A (18y, African American, male), and 1271C (23y, African American, Female), and were designated as Donors 1, 2, 3, and 4, respectively","osteogenic differentiation 7 day","miR-125b",1.25,{"$nulls":4},"RT-qPCR",null,"mean±SEM, Student t test"]
["Differentiating Human Multipotent Mesenchymal Stromal Cells Regulate microRNAs: Prediction of microRNA Regulation by PDGF During Osteogenesis","pooled MSC",null,"1678C (18y, African American, male), 1822A (22y, African American, male), 1832A (18y, African American, male), and 1271C (23y, African American, Female), and were designated as Donors 1, 2, 3, and 4, respectively","treated with the PDGF pathway inhibitor AG-370 during differentiation","miR-125b",6,{"$nulls":4},"RT-qPCR",null,"mean±SEM, Student t test"]
["Differentiating Human Multipotent Mesenchymal Stromal Cells Regulate microRNAs: Prediction of microRNA Regulation by PDGF During Osteogenesis","pooled MSC",null,"1678C (18y, African American, male), 1822A (22y, African American, male), 1832A (18y, African American, male), and 1271C (23y, African American, Female), and were designated as Donors 1, 2, 3, and 4, respectively","treated with the PDGF pathway inhibitor AG-370 during differentiation","miR-125b",0.5,{"$nulls":4},"RT-qPCR",null,"mean±SEM, Student t test"]
["MicroRNA-125b suppresses the proliferation and osteogenic differentiation of human bone marrow-derived mesenchymal stem cells","hBMSCs","bone marrow","four elderly osteoporotic patients","osteoporosis","miR-125b",2,{"$nulls":4},"RT-qPCR"]
["MicroRNA-125b suppresses the proliferation and osteogenic differentiation of human bone marrow-derived mesenchymal stem cells","hBMSCs","bone marrow","four elderly osteoporotic patients",null,"miR-125b",{"$nulls":8},"Osx decrease","down"]
["miR-125b is an adhesion-regulated microRNA that protects mesenchymal stem cells from anoikis","hMSCs",null,null,"control (low density)","miR-125b",0.4,{"$nulls":4},"RT-qPCR",null,"nothing"]
["miR-125b is an adhesion-regulated microRNA that protects mesenchymal stem cells from anoikis","hMSCs",null,null,"control (high density)","miR-125b",1,{"$nulls":4},"RT-qPCR",null,"nothing"]

{"sheet":"mir-130a","index":17,"n_rows":6,"n_cols":19,"rows_kept":6,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["miR-214 targets ATF4 to inhibit bone formation",null,"bone sample",null,"osteoporotic female (70-79 y.o.)","miR-130a",17,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]
["miR-214 targets ATF4 to inhibit bone formation",null,"bone sample",null,"osteoporotic female (80-89 y.o.)","miR-130a",13,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]
["miR-214 targets ATF4 to inhibit bone formation",null,"bone sample",null,"osteoporotic male (70-79 y.o.)","miR-130a",14,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]
["miR-214 targets ATF4 to inhibit bone formation",null,"bone sample",null,"osteoporotic male (80-89 y.o.)","miR-130a",12,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]
["MiR-590-3p regulates osteogenic differentiation of human mesenchymal stem cells by regulating APC gene","HMSCs",null,null,"osteogenic differentiation 25 day","miR-130a",2.25,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]

{"sheet":"mir-133a","index":18,"n_rows":14,"n_cols":19,"rows_kept":14,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["Vitamin K2 promotes mesenchymal stem cell differentiation by inhibiting miR‑133a expression","BMSCs","femoral heads",null,"osteogenic differentiation 1 day","miR-133a",0.8,{"$nulls":4},"RT-qPCR",null,"mean ± SD","VK2 inhibits miRNA‑133a"]
["Vitamin K2 promotes mesenchymal stem cell differentiation by inhibiting miR‑133a expression","BMSCs","femoral heads",null,"osteogenic differentiation 3 day","miR-133a",0.7,{"$nulls":4},"RT-qPCR",null,"mean ± SD","VK2 inhibits miRNA‑133a"]
["Vitamin K2 promotes mesenchymal stem cell differentiation by inhibiting miR‑133a expression","BMSCs","femoral heads",null,"osteogenic differentiation 7 day","miR-133a",0.5,{"$nulls":4},"RT-qPCR",null,"mean ± SD","VK2 inhibits miRNA‑133a"]
["Vitamin K2 promotes mesenchymal stem cell differentiation by inhibiting miR‑133a expression","BMSCs","femoral heads",null,"osteogenic differentiation 14 day","miR-133a",0.05,{"$nulls":4},"RT-qPCR",null,"mean ± SD","VK2 inhibits miRNA‑133a"]
["Next generation bone tissue engineering: Non-viral miR-133a inhibition using collagen-nanohydroxyapatite scaffolds rapidly enhances osteogenesis","hMSCs","bone marrow",null,"collagen-nanohydroxyapatite scaffolds with antagomiR-133a","miR-133a",{"$nulls":11},"up"]
["Next generation bone tissue engineering: Non-viral miR-133a inhibition using collagen-nanohydroxyapatite scaffolds rapidly enhances osteogenesis","hMSCs","bone marrow",null,"osteogenic differentiation 1 day","miR-133a",1.8,{"$nulls":4},"RT-qPCR",null,"mean ± SD, two-way ANOVA"]
["Next generation bone tissue engineering: Non-viral miR-133a inhibition using collagen-nanohydroxyapatite scaffolds rapidly enhances osteogenesis","hMSCs","bone marrow",null,"osteogenic differentiation 3 day","miR-133a",2.7,{"$nulls":4},"RT-qPCR",null,"mean ± SD, two-way ANOVA"]
["Next generation bone tissue engineering: Non-viral miR-133a inhibition using collagen-nanohydroxyapatite scaffolds rapidly enhances osteogenesis","hMSCs","bone marrow",null,"osteogenic differentiation 7 day","miR-133a",1.9,{"$nulls":4},"RT-qPCR",null,"mean ± SD, two-way ANOVA"]
["Next generation bone tissue engineering: Non-viral miR-133a inhibition using collagen-nanohydroxyapatite scaffolds rapidly enhances osteogenesis","hMSCs","bone marrow",null,"osteogenic differentiation 14 day","miR-133a",1.4,{"$nulls":4},"RT-qPCR",null,"mean ± SD, two-way ANOVA"]
["Next generation bone tissue engineering: Non-viral miR-133a inhibition using collagen-nanohydroxyapatite scaffolds rapidly enhances osteogenesis","hMSCs","bone marrow",null,"cell growth medium 1 day","miR-133a",0.9,{"$nulls":4},"RT-qPCR",null,"mean ± SD, two-way ANOVA"]
["Next generation bone tissue engineering: Non-viral miR-133a inhibition using collagen-nanohydroxyapatite scaffolds rapidly enhances osteogenesis","hMSCs","bone marrow",null,"cell growth medium 3 day","miR-133a",1.5,{"$nulls":4},"RT-qPCR",null,"mean ± SD, two-way ANOVA"]
["Next generation bone tissue engineering: Non-viral miR-133a inhibition using collagen-nanohydroxyapatite scaffolds rapidly enhances osteogenesis","hMSCs","bone marrow",null,"cell growth medium 7 day","miR-133a",4.4,{"$nulls":4},"RT-qPCR",null,"mean ± SD, two-way ANOVA"]
["Next generation bone tissue engineering: Non-viral miR-133a inhibition using collagen-nanohydroxyapatite scaffolds rapidly enhances osteogenesis","hMSCs","bone marrow",null,"cell growth medium 14 day","miR-133a",4.7,{"$nulls":4},"RT-qPCR",null,"mean ± SD, two-way ANOVA"]

{"sheet":"mir-137","index":19,"n_rows":8,"n_cols":19,"rows_kept":8,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["MIR-33a-5p modulates TNF-α-inhibited osteogenic differentiation by targeting SATB2 expression in hBMSCs","hBMSCs","bone marrow",null,"control","miR-137",1,{"$nulls":4},"RT-qPCR",null,"nothing"]
["MIR-33a-5p modulates TNF-α-inhibited osteogenic differentiation by targeting SATB2 expression in hBMSCs","hBMSCs","bone marrow",null,"TNF-α treatment 30 min","miR-137",1.5,{"$nulls":4},"RT-qPCR",null,"nothing"]
["MIR-33a-5p modulates TNF-α-inhibited osteogenic differentiation by targeting SATB2 expression in hBMSCs","hBMSCs","bone marrow",null,"TNF-α treatment 30 min + BMP-induced osteogenesis 24 hours","miR-137",1.25,{"$nulls":4},"RT-qPCR",null,"nothing"]
["MIR-33a-5p modulates TNF-α-inhibited osteogenic differentiation by targeting SATB2 expression in hBMSCs","hBMSCs","bone marrow",null,"TNF-α treatment 30 min + BMP-induced osteogenesis 48 hours","miR-137",4.6,{"$nulls":4},"RT-qPCR",null,"nothing"]
["MicroRNAs miR-26a, miR-26b, and miR-29b accelerate osteogenic differentiation of unrestricted somatic stem cells from human cord blood","SA5/73","USSC, human cord blood",null,"7 day after osteogenic stimuli","miR-137",4,{"$nulls":4},"microarrays",null,null,"CDK6 (analysed in HEK293T)"]
["MicroRNAs miR-26a, miR-26b, and miR-29b accelerate osteogenic differentiation of unrestricted somatic stem cells from human cord blood","SA8/25","USSC, human cord blood",null,"7 day after osteogenic stimuli","miR-137",7,{"$nulls":4},"microarrays",null,null,"CDK6 (analysed in HEK293T)"]
["Decoding the regulatory landscape of ageing in musculoskeletal engineered tissues using genome-wide DNA methylation and RNASeq","MSCs",null,"old n = 4 (65.5years±8.3SD) donors, 4 passage","age related changes in osteogenic tissue","miR-137",null,2.42,{"$nulls":3},"RNASeq"]

{"sheet":"mir-138","index":20,"n_rows":27,"n_cols":19,"rows_kept":27,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["Linc-ROR Promotes Osteogenic Differentiation of Mesenchymal Stem Cells by Functioning as a Competing Endogenous RNA for miR-138 and miR-145","MSCs","bone marrow",null,null,"miR-138",{"$nulls":8},"ZEB2 decrease","down",null,null,"linc-ROR acted as a ceRNA for miR-138 and miR- 145"]
["Biomimetic oyster shell – replicated topography alters the behaviour of human skeletal stem cells","SSCs (skeletal stem cells)","bone marrow",null,"osteogenic differentiation on the PCL (nacre) topographies","miR-138",1,{"$nulls":4},"RT-qPCR","ns","mean ± SD"]
["Biomimetic oyster shell – replicated topography alters the behaviour of human skeletal stem cells","SSCs (skeletal stem cells)","bone marrow",null,"osteogenic differentiation on the PCL (prism) topographies","miR-138",1,{"$nulls":4},"RT-qPCR","ns","mean ± SD"]
["MicroRNA-146a regulates human foetal femur derived skeletal stem cell differentiation by down-regulating SMAD2 and SMAD5","SSCs (skeletal stem cells)","foetal femur","7–9 weeks fetuses","osteogenic diaphyseal cells","miR-138",{"$nulls":3},7.79,null,"microarrays",null,"t-test"]
["MicroRNA-146a regulates human foetal femur derived skeletal stem cell differentiation by down-regulating SMAD2 and SMAD11","SSCs (skeletal stem cells)","foetal femur","7–9 weeks fetuses","osteogenic diaphyseal cells","miR-138",0.1,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Mann-Whitney test"]
["Long non-coding RNA H19 mediates mechanical tension-induced osteogenesis of bone marrow mesenchymal stem cells via FAK by sponging miR-138","hBMSCs",null,null,"mechanical tension-induced osteogenesis 1 day","miR-138",0.25,{"$nulls":4},"RT-qPCR",null,"mean±SEM"]
["Long non-coding RNA H19 mediates mechanical tension-induced osteogenesis of bone marrow mesenchymal stem cells via FAK by sponging miR-138","hBMSCs",null,null,"mechanical tension-induced osteogenesis 3 day","miR-138",0.2,{"$nulls":4},"RT-qPCR",null,"mean±SEM"]
["Long non-coding RNA H19 mediates mechanical tension-induced osteogenesis of bone marrow mesenchymal stem cells via FAK by sponging miR-138","hBMSCs",null,null,"mechanical tension-induced osteogenesis 5 day","miR-138",0.175,{"$nulls":4},"RT-qPCR",null,"mean±SEM"]
["Long non-coding RNA H19 mediates mechanical tension-induced osteogenesis of bone marrow mesenchymal stem cells via FAK by sponging miR-138","hBMSCs",null,null,"mechanical tension-induced osteogenesis 7 day","miR-138",0.15,{"$nulls":4},"RT-qPCR",null,"mean±SEM"]
["Long non-coding RNA H19 mediates mechanical tension-induced osteogenesis of bone marrow mesenchymal stem cells via FAK by sponging miR-138","hBMSCs",{"$nulls":3},"miR-138",{"$nulls":8},"PTK2 decrease",null,null,"up","H19 may function as a sponge to hijack miR-138"]
["Adipogenic RNAs are transferred in osteoblasts via bone marrow adipocytes-derived extracellular vesicles ( EVs )","hMSC-Ost","purified",null,"14 days-differentiated osteoblasts incubated with conditioned medium from 14 days-differentiated adipocytes","miR-138",0.45,{"$nulls":4},"RT-qPCR",null,"median of experimental data"]
["MicroRNA-138 regulates osteogenic differentiation of human stromal (mesenchymal) stem cells in vivo","hMSCs","telomerase immortalized bone marrow",null,"osteogenic differentiation 10 day","miR-138",0.7845840978967508,-0.35,{"$nulls":3},"RT-qPCR",null,"mean ± SD","PTK2 decrease"]
["Biochemical and Biophysical Research Communications PDGF-regulated miRNA-138 inhibits the osteogenic differentiation of mesenchymal stem cells","hMSCs","Telomerase-immortalized bone marrow-derived",null,"osteogenesis + PDGF treatment 15 day","miR-138",6.4,{"$nulls":3},0.15625,"RT-qPCR",null,"mean+SEM",null,"down"]
["Biochemical and Biophysical Research Communications PDGF-regulated miRNA-138 inhibits the osteogenic differentiation of mesenchymal stem cells","hMSCs","Telomerase-immortalized bone marrow-derived",null,"osteogenesis + PDGF treatment 2 day","miR-138",4.5,{"$nulls":3},0.2222222222222222,"RT-qPCR",null,"mean+SEM",null,"down"]
["Biochemical and Biophysical Research Communications PDGF-regulated miRNA-138 inhibits the osteogenic differentiation of mesenchymal stem cells","hMSCs","Telomerase-immortalized bone marrow-derived",null,"osteogenesis + PDGF treatment 4 day","miR-138",5.3,{"$nulls":3},0.18867924528301888,"RT-qPCR",null,"mean+SEM",null,"down"]
["Biochemical and Biophysical Research Communications PDGF-regulated miRNA-138 inhibits the osteogenic differentiation of mesenchymal stem cells","hMSCs","Telomerase-immortalized bone marrow-derived",null,"osteogenesis + PDGF treatment 6 day","miR-138",5,{"$nulls":3},0.2,"RT-qPCR",null,"mean+SEM",null,"down"]
["Biochemical and Biophysical Research Communications PDGF-regulated miRNA-138 inhibits the osteogenic differentiation of mesenchymal stem cells","hMSCs","Telomerase-immortalized bone marrow-derived",null,"osteogenesis + PDGF treatment 8 day","miR-138",5.3,{"$nulls":3},0.18867924528301888,"RT-qPCR",null,"mean+SEM",null,"down"]
["Biochemical and Biophysical Research Communications PDGF-regulated miRNA-138 inhibits the osteogenic differentiation of mesenchymal stem cells","hMSCs","Telomerase-immortalized bone marrow-derived",null,"osteogenesis + PDGF treatment 10 day","miR-138",5.5,{"$nulls":3},0.18181818181818182,"RT-qPCR",null,"mean+SEM",null,"down"]
["Biochemical and Biophysical Research Communications PDGF-regulated miRNA-138 inhibits the osteogenic differentiation of mesenchymal stem cells","hMSCs","Telomerase-immortalized bone marrow-derived",null,"osteogenesis + PDGF treatment 12 day","miR-138",5,{"$nulls":3},0.2,"RT-qPCR",null,"mean+SEM",null,"down"]
["Biochemical and Biophysical Research Communications PDGF-regulated miRNA-138 inhibits the osteogenic differentiation of mesenchymal stem cells","hMSCs","Telomerase-immortalized bone marrow-derived",null,"osteogenesis + PDGF treatment 14 day","miR-138",5.4,{"$nulls":3},0.18518518518518517,"RT-qPCR",null,"mean+SEM",null,"down"]
["Biochemical and Biophysical Research Communications PDGF-regulated miRNA-138 inhibits the osteogenic differentiation of mesenchymal stem cells","hMSCs","Telomerase-immortalized bone marrow-derived",null,"osteogenesis + PDGF treatment 16 day","miR-138",4.9,{"$nulls":3},0.2040816326530612,"RT-qPCR",null,"mean+SEM",null,"down"]
["Differentiating Human Multipotent Mesenchymal Stromal Cells Regulate microRNAs: Prediction of microRNA Regulation by PDGF During Osteogenesis","MSC",null,"1678C (18y, African American, male), 1822A (22y, African American, male), 1832A (18y, African American, male), and 1271C (23y, African American, Female), and were designated as Donors 1, 2, 3, and 4, respectively","osteogenic differentiation 7 day","miR-138",5,{"$nulls":3},0.2,"RT-qPCR",null,"mean±SEM, Student t test"]
["Differentiating Human Multipotent Mesenchymal Stromal Cells Regulate microRNAs: Prediction of microRNA Regulation by PDGF During Osteogenesis","MSC",null,"1678C (18y, African American, male), 1822A (22y, African American, male), 1832A (18y, African American, male), and 1271C (23y, African American, Female), and were designated as Donors 1, 2, 3, and 4, respectively","osteogenic differentiation 7 day","miR-138",2.5,{"$nulls":3},0.4,"RT-qPCR",null,"mean±SEM, Student t test"]
["Differentiating Human Multipotent Mesenchymal Stromal Cells Regulate microRNAs: Prediction of microRNA Regulation by PDGF During Osteogenesis","pooled MSC",null,"1678C (18y, African American, male), 1822A (22y, African American, male), 1832A (18y, African American, male), and 1271C (23y, African American, Female), and were designated as Donors 1, 2, 3, and 4, respectively","treated with the PDGF pathway inhibitor AG-370 during differentiation","miR-138",6.5,{"$nulls":3},0.15384615384615385,"RT-qPCR",null,"mean±SEM, Student t test"]
["Differentiating Human Multipotent Mesenchymal Stromal Cells Regulate microRNAs: Prediction of microRNA Regulation by PDGF During Osteogenesis","pooled MSC",null,"1678C (18y, African American, male), 1822A (22y, African American, male), 1832A (18y, African American, male), and 1271C (23y, African American, Female), and were designated as Donors 1, 2, 3, and 4, respectively","treated with the PDGF pathway inhibitor AG-370 during differentiation","miR-138",1.75,{"$nulls":3},0.5714285714285714,"RT-qPCR",null,"mean±SEM, Student t test"]
["MicroRNA-138 regulates osteogenic differentiation of human stromal (mesenchymal) stem cells in vivo","hMSCs","telomerase immortalized bone marrow",null,"osteogenic differentiation 10 day","miR-138 ",0.9201876506248752,-0.12,{"$nulls":3},"microarrays",null,"mean ± SD","PTK2 decrease"]

{"sheet":"mir-140","index":21,"n_rows":8,"n_cols":19,"rows_kept":8,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["MiR-1827 inhibits osteogenic differentiation by targeting IGF1 in MSMSCs","MSMSCs","maxillary sinus membrane stem cells","16 individuals aged 18–29 years ","osteogenic differentiation 3 day","miR-140",0.95,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]
["MicroRNA-146a regulates human foetal femur derived skeletal stem cell differentiation by down-regulating SMAD2 and SMAD10","SSCs (skeletal stem cells)","foetal femur","7–9 weeks fetuses","osteogenic diaphyseal cells","miR-140",0.6,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Mann-Whitney test"]
["miR-214 targets ATF4 to inhibit bone formation",null,"bone sample",null,"osteoporotic female (70-79 y.o.)","miR-140",8,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]
["miR-214 targets ATF4 to inhibit bone formation",null,"bone sample",null,"osteoporotic female (80-89 y.o.)","miR-140",9.5,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]
["miR-214 targets ATF4 to inhibit bone formation",null,"bone sample",null,"osteoporotic male (70-79 y.o.)","miR-140",6,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]
["miR-214 targets ATF4 to inhibit bone formation",null,"bone sample",null,"osteoporotic male (80-89 y.o.)","miR-140",7,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]
["Decoding the regulatory landscape of ageing in musculoskeletal engineered tissues using genome-wide DNA methylation and RNASeq","MSCs",null,"old n = 4 (65.5years±8.3SD) donors, 4 passage","age related changes in osteogenic tissue","miR-140",54.568633073149215,5.77,{"$nulls":3},"RT-qPCR",null,"mean±SEM"]

{"sheet":"mir-143","index":22,"n_rows":8,"n_cols":19,"rows_kept":8,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["MicroRNA-138 regulates osteogenic differentiation of human stromal (mesenchymal) stem cells in vivo","hMSCs","telomerase immortalized bone marrow",null,"osteogenic differentiation 10 day","miR-143",3.890619789649142,1.96,{"$nulls":3},"RT-qPCR",null,"mean ± SD"]
["Differentiating Human Multipotent Mesenchymal Stromal Cells Regulate microRNAs: Prediction of microRNA Regulation by PDGF During Osteogenesis","MSC",null,"1678C (18y, African American, male), 1822A (22y, African American, male), 1832A (18y, African American, male), and 1271C (23y, African American, Female), and were designated as Donors 1, 2, 3, and 4, respectively","osteogenic differentiation 7 day","miR-143",4,{"$nulls":4},"RT-qPCR",null,"mean±SEM, Student t test"]
["Differentiating Human Multipotent Mesenchymal Stromal Cells Regulate microRNAs: Prediction of microRNA Regulation by PDGF During Osteogenesis","MSC",null,"1678C (18y, African American, male), 1822A (22y, African American, male), 1832A (18y, African American, male), and 1271C (23y, African American, Female), and were designated as Donors 1, 2, 3, and 4, respectively","osteogenic differentiation 7 day","miR-143",1.4,{"$nulls":4},"RT-qPCR",null,"mean±SEM, Student t test"]
["MicroRNA-138 regulates osteogenic differentiation of human stromal (mesenchymal) stem cells in vivo","hMSCs","telomerase immortalized bone marrow",null,"osteogenic differentiation 10 day","miR-143 ",1.9861849908740716,0.99,{"$nulls":3},"microarrays",null,"mean ± SD"]
["Differentiating Human Multipotent Mesenchymal Stromal Cells Regulate microRNAs: Prediction of microRNA Regulation by PDGF During Osteogenesis","pooled MSC",null,"1678C (18y, African American, male), 1822A (22y, African American, male), 1832A (18y, African American, male), and 1271C (23y, African American, Female), and were designated as Donors 1, 2, 3, and 4, respectively","treated with the PDGF pathway inhibitor AG-370 during differentiation","miR-143",3.8,{"$nulls":4},"RT-qPCR",null,"mean±SEM, Student t test"]
["Differentiating Human Multipotent Mesenchymal Stromal Cells Regulate microRNAs: Prediction of microRNA Regulation by PDGF During Osteogenesis","pooled MSC",null,"1678C (18y, African American, male), 1822A (22y, African American, male), 1832A (18y, African American, male), and 1271C (23y, African American, Female), and were designated as Donors 1, 2, 3, and 4, respectively","treated with the PDGF pathway inhibitor AG-370 during differentiation","miR-143",0.75,{"$nulls":4},"RT-qPCR",null,"mean±SEM, Student t test"]
["MicroRNA-146a regulates human foetal femur derived skeletal stem cell differentiation by down-regulating SMAD2 and SMAD6","SSCs (skeletal stem cells)","foetal femur","7–9 weeks fetuses","osteogenic diaphyseal cells","miR-143",{"$nulls":3},5.97,null,"microarrays",null,"t-test"]

{"sheet":"mir-145","index":23,"n_rows":6,"n_cols":19,"rows_kept":6,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["MicroRNA expression pro fi ling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-58","MSCs","bone marrow","3 donors","full confluence of the culture after the addition of the differentiating medium vs control","miR-145",1.8970109416456606,0.923728,{"$nulls":3},"microarrays"]
["MicroRNA expression pro fi ling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-59","MSCs","bone marrow","3 donors","full confluence of the culture after the addition of the differentiating medium vs control","miR-145",3.9447120706245378,1.97992,{"$nulls":3},"microarrays"]
["MicroRNA expression pro fi ling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-60","MSCs","bone marrow","3 donors","full confluence of the culture after the addition of the differentiating medium vs control","miR-145",1.5181433257836927,0.602308,{"$nulls":3},"microarrays"]
["Linc-ROR Promotes Osteogenic Differentiation of Mesenchymal Stem Cells by Functioning as a Competing Endogenous RNA for miR-138 and miR-145","MSCs","bone marrow",null,null,"miR-145",{"$nulls":8},"ZEB2 decrease","down",null,null,"linc-ROR acted as a ceRNA for miR-138 and miR- 145"]
["MicroRNA-146a regulates human foetal femur derived skeletal stem cell differentiation by down-regulating SMAD2 and SMAD9","SSCs (skeletal stem cells)","foetal femur","7–9 weeks fetuses","osteogenic diaphyseal cells","miR-145",{"$nulls":3},4.81,null,"microarrays",null,"t-test"]

{"sheet":"mir-146a","index":24,"n_rows":10,"n_cols":19,"rows_kept":10,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["MIR146A inhibits JMJD3 expression and osteogenic differentiation in human mesenchymal stem cells","hMSCs","umbilical cord","ATCC","osteogenic differentiation","miR-146a",0.25,{"$nulls":4},"RT-qPCR",null,"mean±SEM, Student t test","JMJD3 inhibition"]
["MicroRNA expression pro fi ling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-88","MSCs","bone marrow","3 donors","full confluence of the culture after the addition of the differentiating medium vs control","miR-146a",null,"−0.972296  ",{"$nulls":3},"microarrays"]
["MicroRNA expression pro fi ling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-89","MSCs","bone marrow","3 donors","full confluence of the culture after the addition of the differentiating medium vs control","miR-146a",null,"−1.39036",{"$nulls":3},"microarrays"]
["MicroRNA expression pro fi ling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-90","MSCs","bone marrow","3 donors","full confluence of the culture after the addition of the differentiating medium vs control","miR-146a",null,"−1.66767",{"$nulls":3},"microarrays"]
["MicroRNA-146a regulates human foetal femur derived skeletal stem cell differentiation by down-regulating SMAD2 and SMAD7","SSCs (skeletal stem cells)","foetal femur","7–9 weeks fetuses","osteogenic diaphyseal cells","miR-146a",{"$nulls":3},9.25,null,"microarrays",null,"t-test"]
["MicroRNA-146a regulates human foetal femur derived skeletal stem cell differentiation by down-regulating SMAD2 and SMAD13","SSCs (skeletal stem cells)","foetal femur","7–9 weeks fetuses",null,"miR-146a",{"$nulls":8},"SMAD2 decrease","up"]
["MicroRNA-146a regulates human foetal femur derived skeletal stem cell differentiation by down-regulating SMAD2 and SMAD14","SSCs (skeletal stem cells)","foetal femur","7–9 weeks fetuses",null,"miR-146a",{"$nulls":8},"SMAD3 decrease","up"]
["NF- k B Activation Stimulates Osteogenic Differentiation of Mesenchymal Stem Cells Derived from Human Adipose Tissue by Increasing TAZ Expression","hADSC","adipose tissue","3 patients (61 year-old male, 54 year- old male, and 52 year-old female)","overexpression of miR; TNF-a and TLR ligand treatment","miR-146a",{"$nulls":8},"total and phospho-IRAK1 decrease","down"]
["MicroRNA-146a regulates human foetal femur derived skeletal stem cell differentiation by down-regulating SMAD2 and SMAD12","SSCs (skeletal stem cells)","foetal femur","7–9 weeks fetuses","osteogenic diaphyseal cells","miR-146a",50,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Mann-Whitney test"]

{"sheet":"mir-146b-5p","index":25,"n_rows":11,"n_cols":19,"rows_kept":11,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["Modulation of Micro RNA Expression and Osteoblast Differentiation by Nanotopography","hMSCs",null,null,"mechanical induction of osteogenesis 14 day","miR-146b-5p",1.783,{"$nulls":4},"RNA-Seq",null,"t test"]
["Osteogenic Differentiation of MSC through Calcium Signaling Activation : Transcriptomics and Functional Analysis","hMSCs","bone marrow",null,"calcium-based scaffolds induced osteogenic differentiation 5 day vs 0 day","miR-146b-5p",2.2193179082192422,"1,15011634250577",{"$nulls":3},"microarrays",null,"mean±SEM"]
["miR-195 in human primary mesenchymal stromal/stem cells regulates proliferation, osteogenesis and paracrine effect on angiogenesis","MC3T3",null,null,"7 day after osteogenic stimuli","miR-146b-5p",1.215,{"$nulls":4},"RT-qPCR","up","mean±SD, Student t test"]
["miR-195 in human primary mesenchymal stromal/stem cells regulates proliferation, osteogenesis and paracrine effect on angiogenesis","MSC",null,null,"3 day after osteogenic stimuli","miR-146b-5p",0.5,{"$nulls":4},"RT-qPCR","down","mean±SEM, Student t test"]
["miR-195 in human primary mesenchymal stromal/stem cells regulates proliferation, osteogenesis and paracrine effect on angiogenesis","MSC",null,null,"7 day after osteogenic stimuli","miR-146b-5p",0.75,{"$nulls":4},"RT-qPCR","down","mean±SEM, Student t test"]
["miR-195 in human primary mesenchymal stromal/stem cells regulates proliferation, osteogenesis and paracrine effect on angiogenesis","MSC",null,null,"14 day after osteogenic stimuli","miR-146b-5p",0.75,{"$nulls":4},"RT-qPCR","down","mean±SEM, Student t test"]
["miR-195 in human primary mesenchymal stromal/stem cells regulates proliferation, osteogenesis and paracrine effect on angiogenesis","MSC",null,null,"21 day after osteogenic stimuli","miR-146b-5p",0.75,{"$nulls":4},"RT-qPCR","down","mean±SEM, Student t test"]
["miR-195 in human primary mesenchymal stromal/stem cells regulates proliferation, osteogenesis and paracrine effect on angiogenesis","MSC",null,null,"28 day after osteogenic stimuli","miR-146b-5p",1.1,{"$nulls":4},"RT-qPCR",null,"mean±SEM, Student t test"]
["MicroRNA-146a regulates human foetal femur derived skeletal stem cell differentiation by down-regulating SMAD2 and SMAD3","SSCs (skeletal stem cells)","foetal femur","7–9 weeks fetuses","osteogenic diaphyseal cells","miR-146b-5p",{"$nulls":3},8.04,null,"microarrays",null,"t-test"]
["miR-195 in human primary mesenchymal stromal/stem cells regulates proliferation, osteogenesis and paracrine effect on angiogenesis",{"$nulls":3},"3 day after osteogenic stimuli","miR-146b-5p",{"$nulls":5},"RT-qPCR","ns","mean±SD, Student t test"]

{"sheet":"mir-148a","index":26,"n_rows":34,"n_cols":19,"rows_kept":34,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["The Effects of BMP-2, miR-31, miR-106a, and miR-148a on Osteogenic Differentiation of MSCs Derived from Amnion in Comparison with MSCs Derived from the Bone Marrow","AM-MSCs","amniotic tissues","4 donors","osteogenic differentiation 3 day","miR-148a",0.94,{"$nulls":4},"RT-qPCR",null,"mean±SEM, unpaired t test"]
["The Effects of BMP-2, miR-31, miR-106a, and miR-148a on Osteogenic Differentiation of MSCs Derived from Amnion in Comparison with MSCs Derived from the Bone Marrow","AM-MSCs","amniotic tissues","4 donors","osteogenic differentiation 14 day","miR-148a",0.88,{"$nulls":4},"RT-qPCR",null,"mean±SEM, unpaired t test"]
["The Effects of BMP-2, miR-31, miR-106a, and miR-148a on Osteogenic Differentiation of MSCs Derived from Amnion in Comparison with MSCs Derived from the Bone Marrow","AM-MSCs","amniotic tissues","4 donors","osteogenic differentiation 21 day","miR-148a",0.8,{"$nulls":4},"RT-qPCR",null,"mean±SEM, unpaired t test"]
["The Effects of BMP-2, miR-31, miR-106a, and miR-148a on Osteogenic Differentiation of MSCs Derived from Amnion in Comparison with MSCs Derived from the Bone Marrow","AM-MSCs","amniotic tissues","4 donors","osteogenic differentiation 28 day","miR-148a",0.7,{"$nulls":4},"RT-qPCR",null,"mean±SEM, unpaired t test"]
["The Effects of BMP-2, miR-31, miR-106a, and miR-148a on Osteogenic Differentiation of MSCs Derived from Amnion in Comparison with MSCs Derived from the Bone Marrow","AM-MSCs","amniotic tissues","4 donors","BMP-2 induced osteogenic differentiation 3 day","miR-148a",0.9,{"$nulls":4},"RT-qPCR",null,"mean±SEM, unpaired t test"]
["The Effects of BMP-2, miR-31, miR-106a, and miR-148a on Osteogenic Differentiation of MSCs Derived from Amnion in Comparison with MSCs Derived from the Bone Marrow","AM-MSCs","amniotic tissues","4 donors","BMP-2 induced osteogenic differentiation 7 day","miR-148a",0.9,{"$nulls":4},"RT-qPCR",null,"mean±SEM, unpaired t test"]
["The Effects of BMP-2, miR-31, miR-106a, and miR-148a on Osteogenic Differentiation of MSCs Derived from Amnion in Comparison with MSCs Derived from the Bone Marrow","AM-MSCs","amniotic tissues","4 donors","BMP-2 induced osteogenic differentiation 14 day","miR-148a",0.82,{"$nulls":4},"RT-qPCR",null,"mean±SEM, unpaired t test"]
["The Effects of BMP-2, miR-31, miR-106a, and miR-148a on Osteogenic Differentiation of MSCs Derived from Amnion in Comparison with MSCs Derived from the Bone Marrow","AM-MSCs","amniotic tissues","4 donors","BMP-2 induced osteogenic differentiation 21 day","miR-148a",0.72,{"$nulls":4},"RT-qPCR",null,"mean±SEM, unpaired t test"]
["The Effects of BMP-2, miR-31, miR-106a, and miR-148a on Osteogenic Differentiation of MSCs Derived from Amnion in Comparison with MSCs Derived from the Bone Marrow","AM-MSCs","amniotic tissues","4 donors","BMP-2 induced osteogenic differentiation 28 day","miR-148a",0.65,{"$nulls":4},"RT-qPCR",null,"mean±SEM, unpaired t test"]
["The Effects of BMP-2, miR-31, miR-106a, and miR-148a on Osteogenic Differentiation of MSCs Derived from Amnion in Comparison with MSCs Derived from the Bone Marrow","BMMSCs","bone marrow","healthy donors (n =4) were <60 years","osteogenic differentiation 3 day","miR-148a",0.65,{"$nulls":4},"RT-qPCR",null,"mean±SEM, unpaired t test"]
["The Effects of BMP-2, miR-31, miR-106a, and miR-148a on Osteogenic Differentiation of MSCs Derived from Amnion in Comparison with MSCs Derived from the Bone Marrow","BMMSCs","bone marrow","healthy donors (n =4) were <60 years","osteogenic differentiation 7 day","miR-148a",0.6,{"$nulls":4},"RT-qPCR",null,"mean±SEM, unpaired t test"]
["The Effects of BMP-2, miR-31, miR-106a, and miR-148a on Osteogenic Differentiation of MSCs Derived from Amnion in Comparison with MSCs Derived from the Bone Marrow","BMMSCs","bone marrow","healthy donors (n =4) were <60 years","osteogenic differentiation 14 day","miR-148a",0.52,{"$nulls":4},"RT-qPCR",null,"mean±SEM, unpaired t test"]
["The Effects of BMP-2, miR-31, miR-106a, and miR-148a on Osteogenic Differentiation of MSCs Derived from Amnion in Comparison with MSCs Derived from the Bone Marrow","BMMSCs","bone marrow","healthy donors (n =4) were <60 years","osteogenic differentiation 21 day","miR-148a",0.48,{"$nulls":4},"RT-qPCR",null,"mean±SEM, unpaired t test"]
["The Effects of BMP-2, miR-31, miR-106a, and miR-148a on Osteogenic Differentiation of MSCs Derived from Amnion in Comparison with MSCs Derived from the Bone Marrow","BMMSCs","bone marrow","healthy donors (n =4) were <60 years","osteogenic differentiation 28 day","miR-148a",0.44,{"$nulls":4},"RT-qPCR",null,"mean±SEM, unpaired t test"]
["The Effects of BMP-2, miR-31, miR-106a, and miR-148a on Osteogenic Differentiation of MSCs Derived from Amnion in Comparison with MSCs Derived from the Bone Marrow","BMMSCs","bone marrow","healthy donors (n =4) were <60 years","BMP-2 induced osteogenic differentiation 3 day","miR-148a",0.6,{"$nulls":4},"RT-qPCR",null,"mean±SEM, unpaired t test"]
["The Effects of BMP-2, miR-31, miR-106a, and miR-148a on Osteogenic Differentiation of MSCs Derived from Amnion in Comparison with MSCs Derived from the Bone Marrow","BMMSCs","bone marrow","healthy donors (n =4) were <60 years","BMP-2 induced osteogenic differentiation 7 day","miR-148a",0.52,{"$nulls":4},"RT-qPCR",null,"mean±SEM, unpaired t test"]
["The Effects of BMP-2, miR-31, miR-106a, and miR-148a on Osteogenic Differentiation of MSCs Derived from Amnion in Comparison with MSCs Derived from the Bone Marrow","BMMSCs","bone marrow","healthy donors (n =4) were <60 years","BMP-2 induced osteogenic differentiation 14 day","miR-148a",0.43,{"$nulls":4},"RT-qPCR",null,"mean±SEM, unpaired t test"]
["The Effects of BMP-2, miR-31, miR-106a, and miR-148a on Osteogenic Differentiation of MSCs Derived from Amnion in Comparison with MSCs Derived from the Bone Marrow","BMMSCs","bone marrow","healthy donors (n =4) were <60 years","BMP-2 induced osteogenic differentiation 21 day","miR-148a",0.36,{"$nulls":4},"RT-qPCR",null,"mean±SEM, unpaired t test"]
["The Effects of BMP-2, miR-31, miR-106a, and miR-148a on Osteogenic Differentiation of MSCs Derived from Amnion in Comparison with MSCs Derived from the Bone Marrow","BMMSCs","bone marrow","healthy donors (n =4) were <60 years","BMP-2 induced osteogenic differentiation 28 day","miR-148a",0.33,{"$nulls":4},"RT-qPCR",null,"mean±SEM, unpaired t test"]
["Altered MicroRNA Expression Profile in Exosomes during Osteogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells","BMSCs","bone marrow",null,"exosomes during osteogenic differentiation","miR-148a",2.284,{"$nulls":4},"microarrays"]
["Altered MicroRNA Expression Profile in Exosomes during Osteogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells","BMSCs","bone marrow",null,"exosomes during osteogenic differentiation 0,5 day","miR-148a",1.5,{"$nulls":4},"RT-qPCR",null,"mean±SEM"]
["Altered MicroRNA Expression Profile in Exosomes during Osteogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells","BMSCs","bone marrow",null,"exosomes during osteogenic differentiation 1 day","miR-148a",3.1,{"$nulls":4},"RT-qPCR",null,"mean±SEM"]
["Altered MicroRNA Expression Profile in Exosomes during Osteogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells","BMSCs","bone marrow",null,"exosomes during osteogenic differentiation 1,5 day","miR-148a",2.2,{"$nulls":4},"RT-qPCR",null,"mean±SEM"]
["Altered MicroRNA Expression Profile in Exosomes during Osteogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells","BMSCs","bone marrow",null,"exosomes during osteogenic differentiation 2 day","miR-148a",1.6,{"$nulls":4},"RT-qPCR",null,"mean±SEM"]
["Altered MicroRNA Expression Profile in Exosomes during Osteogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells","BMSCs","bone marrow",null,"exosomes during osteogenic differentiation 2,5 day","miR-148a",1.4,{"$nulls":4},"RT-qPCR",null,"mean±SEM"]
["Altered MicroRNA Expression Profile in Exosomes during Osteogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells","BMSCs","bone marrow",null,"exosomes during osteogenic differentiation 3 day","miR-148a",1.7,{"$nulls":4},"RT-qPCR",null,"mean±SEM"]
["Altered MicroRNA Expression Profile in Exosomes during Osteogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells","BMSCs","bone marrow",null,"exosomes during osteogenic differentiation 4 day","miR-148a",1.7,{"$nulls":4},"RT-qPCR",null,"mean±SEM"]
["Altered MicroRNA Expression Profile in Exosomes during Osteogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells","BMSCs","bone marrow",null,"exosomes during osteogenic differentiation 5 day","miR-148a",2,{"$nulls":4},"RT-qPCR",null,"mean±SEM"]
["Altered MicroRNA Expression Profile in Exosomes during Osteogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells","BMSCs","bone marrow",null,"exosomes during osteogenic differentiation 7 day","miR-148a",2.1,{"$nulls":4},"RT-qPCR",null,"mean±SEM"]
["The effects of hedgehog on RNA binding protein Msi1 during the osteogenic differentiation of human cord blood-derived mesenchymal stem cells","hUCB-MSCs","umbilical cord blood",null,"osteogenic differentiation 21 day ","miR-148a",2.4,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]
["ACVR1, a Therapeutic Target of Fibrodysplasia Ossificans Progressiva, Is Negatively Regulated by miR-148a","HeLA",{"$nulls":3},"miR-148a",{"$nulls":3},"down",{"$nulls":4},"ACVR1 decrease"]
["The Effects of BMP-2, miR-31, miR-106a, and miR-148a on Osteogenic Differentiation of MSCs Derived from Amnion in Comparison with MSCs Derived from the Bone Marrow",{"$nulls":4},"miR-148a",{"$nulls":11},"up"]
["The effects of hedgehog on RNA binding protein Msi1 during the osteogenic differentiation of human cord blood-derived mesenchymal stem cells","hUCB-MSCs","umbilical cord blood",null,"osteogenic differentiation 21 day + purmorphamine (activates the Hh pathway)","miR-148a",1.9,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]

{"sheet":"mir-148b","index":27,"n_rows":7,"n_cols":19,"rows_kept":7,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["Osteogenic Differentiation of Human Amniotic Fluid Mesenchymal Stem Cells Is Determined by Epigenetic Changes","AF-MSCs","amniotic fluid","second trimester, healthy women","osteogenic differentiation 5 day","miR-148b",0.6,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]
["Osteogenic Differentiation of Human Amniotic Fluid Mesenchymal Stem Cells Is Determined by Epigenetic Changes","AF-MSCs","amniotic fluid","second trimester, healthy women","osteogenic differentiation 9 day","miR-148b",1.5,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]
["Osteogenic Differentiation of Human Amniotic Fluid Mesenchymal Stem Cells Is Determined by Epigenetic Changes","AF-MSCs","amniotic fluid","second trimester, healthy women","osteogenic differentiation 15 day","miR-148b",1,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]
["Manipulation of miRNA activity accelerates osteogenic differentiation of hMSCs in engineered 3D scaffolds","BMSCs",null,null,"osteodenesis + mimic-miR-148b transfection","miR-148b",{"$nulls":8},"ALP increase","up",null,null,"enhance the response to DEX, leading to elevated ALP"]
["The effects of hedgehog on RNA binding protein Msi1 during the osteogenic differentiation of human cord blood-derived mesenchymal stem cells","hUCB-MSCs","umbilical cord blood",null,"osteogenic differentiation 21 day ","miR-148b",3,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]
["The effects of hedgehog on RNA binding protein Msi1 during the osteogenic differentiation of human cord blood-derived mesenchymal stem cells","hUCB-MSCs","umbilical cord blood",null,"osteogenic differentiation 21 day + purmorphamine (activates the Hh pathway)","miR-148b",2,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]

{"sheet":"mir-182","index":28,"n_rows":3,"n_cols":19,"rows_kept":3,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["Loss of Rictor with aging in osteoblasts promotes age-related bone loss","MC3T3-E1","preosteoblast cell line",null,"aging (16 months)","miR-182",0,{"$nulls":4},"RT-qPCR",null,"mean+SEM"]
["Long noncoding RNA related to periodontitis interacts with miR-182 to upregulate osteogenic differentiation in periodontal mesenchymal stem cells of periodontitis patients",{"$nulls":4},"miR-182",{"$nulls":9},"up"]

{"sheet":"mir-199a-3p","index":29,"n_rows":4,"n_cols":19,"rows_kept":4,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["Novel 3D bone marrow niche model Investigating osteogenic differentiation in multiple myeloma using a novel 3D bone marrow niche model","MSCs","bone marrow","healthy donors",null,"miR-199a-3p",{"$nulls":9},"up"]
["MiRNA expression in the cartilage of patients with osteoarthritis",null,"femoral heads","29 OA patients","osteoarthritis","miR-199a-3p",1.2,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]
["Modulation of Micro RNA Expression and Osteoblast Differentiation by Nanotopography","hMSCs",null,null,"mechanical induction of osteogenesis 14 day","miR-199a-3p","1.965",{"$nulls":4},"RNA-Seq",null,"t test"]

{"sheet":"mir-199a-5p","index":30,"n_rows":7,"n_cols":19,"rows_kept":7,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["Altered function in cartilage derived mesenchymal stem cell leads to OA-related cartilage erosion","CMSC","medial and lateral condyles","12 patients (4 males, 8 females, median age 67.8 years, range 47-79 years)","osteoarthritis","miR-199a-5p",null,"-0.856945",{"$nulls":3},"microarrays"]
["Altered function in cartilage derived mesenchymal stem cell leads to OA-related cartilage erosion","CMSC","medial and lateral condyles","12 patients (4 males, 8 females, median age 67.8 years, range 47-79 years)","osteoarthritis","miR-199a-5p",1.1,{"$nulls":4},"RT-qPCR",null,"mean+SEM"]
["Altered function in cartilage derived mesenchymal stem cell leads to OA-related cartilage erosion","CMSC","medial and lateral condyles","12 patients (4 males, 8 females, median age 67.8 years, range 47-79 years)","osteoarthritis","miR-199a-5p",1.4,{"$nulls":4},"RT-qPCR",null,"mean+SEM"]
["Novel 3D bone marrow niche model Investigating osteogenic differentiation in multiple myeloma using a novel 3D bone marrow niche model","MSCs","bone marrow","healthy donors","MSCs cocultured with GFP1-MM1S + osteogenic differentiation 14 day","miR-199a-5p","–2.019",{"$nulls":6},"mean±SEM, two-tailed t test"]
["Novel 3D bone marrow niche model Investigating osteogenic differentiation in multiple myeloma using a novel 3D bone marrow niche model","MSCs","bone marrow","MM patients ","MSCs from myeloma patients ","miR-199a-5p","–1.917",{"$nulls":6},"mean±SEM, two-tailed t test"]
["Novel 3D bone marrow niche model Investigating osteogenic differentiation in multiple myeloma using a novel 3D bone marrow niche model","MSCs","bone marrow","healthy donors",null,"miR-199a-5p",{"$nulls":9},"up"]

{"sheet":"mir-20a","index":31,"n_rows":5,"n_cols":19,"rows_kept":5,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["Sustained localized presentation of RNA interfering molecules from in situ forming hydrogels to guide stem cell osteogenic differentiation","hMSCs",null,null,"in situ forming PEG hydrogels with miR-20a","miR-20a",{"$nulls":9},"up"]
["MicroRNA expression pro fi ling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-100","MSCs","bone marrow","3 donors","full confluence of the culture after the addition of the differentiating medium vs control","miR-20a",null,"−0.513732",{"$nulls":3},"microarrays"]
["MicroRNA expression pro fi ling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-101","MSCs","bone marrow","3 donors","full confluence of the culture after the addition of the differentiating medium vs control","miR-20a",null,"−0.678728 ",{"$nulls":3},"microarrays"]
["MicroRNA expression pro fi ling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-102","MSCs","bone marrow","3 donors","full confluence of the culture after the addition of the differentiating medium vs control","miR-20a",null,"−1.07937",{"$nulls":3},"microarrays"]

{"sheet":"mir-204","index":32,"n_rows":3,"n_cols":19,"rows_kept":3,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["Evidence for Altered Canonical Wnt Signaling in the Trabecular Bone of Elderly Postmenopausal Women with Fragility Femoral Fracture","bone sample","intertrochanteric region of the femur","29 female patients","osteoarthritis","miR-204",0.028,{"$nulls":4},"RT-qPCR"]
["Evidence for Altered Canonical Wnt Signaling in the Trabecular Bone of Elderly Postmenopausal Women with Fragility Femoral Fracture","bone sample","intertrochanteric region of the femur","25 female patients","bone fracture","miR-204",0.02,{"$nulls":4},"RT-qPCR"]

{"sheet":"mir-204-5p","index":33,"n_rows":4,"n_cols":19,"rows_kept":4,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["Modulation of Micro RNA Expression and Osteoblast Differentiation by Nanotopography","hMSCs",null,null,"mechanical induction of osteogenesis 14 day","miR-204-5p","3.855",{"$nulls":4},"RNA-Seq",null,"t test"]
["miR-195 in human primary mesenchymal stromal/stem cells regulates proliferation, osteogenesis and paracrine effect on angiogenesis","MC3T3",null,null,"3 day after osteogenic stimuli","miR-204-5p",0.417,{"$nulls":4},"RT-qPCR","up","mean±SD, Student t test"]
["miR-195 in human primary mesenchymal stromal/stem cells regulates proliferation, osteogenesis and paracrine effect on angiogenesis","MC3T3",null,null,"7 day after osteogenic stimuli","miR-204-5p",0.845,{"$nulls":4},"RT-qPCR","up","mean±SD, Student t test"]

{"sheet":"mir-206","index":34,"n_rows":6,"n_cols":19,"rows_kept":6,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["Bone marrow stromal / stem cell- derived extracellular vesicles regulate osteoblast activity and differentiation in vitro and promote bone regeneration in vivo","BMSCs",null,"2 donors","miR-206 treatment","miR-206",{"$nulls":9},"up"]
["Expression of miR-206 in Human Knee Articular Chondrocytes and Effects of miR-206 on Proliferation and Apoptosis of Articular Chondrocytes","chondrocytes ","femoral condyles",30,"osteoarthritis","miR-206",5,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]
["Expression of miR-206 in Human Knee Articular Chondrocytes and Effects of miR-206 on Proliferation and Apoptosis of Articular Chondrocytes","chondrocytes ","femoral condyles",19,"non-osteoarthritis","miR-206",1.7,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]
["MiR-27a is Essential for the Shift from Osteogenic Differentiation to Adipogenic Differentiation of Mesenchymal Stem Cells in Postmenopausal Osteoporosis",null,"serum",null,"osteoporosis","miR-206",101.2773,{"$nulls":4},"microarrays"]
["Differentially Expressed MicroRNAs in Conservatively Treated Nontraumatic Osteonecrosis Compared with Healthy Controls",null,null,"43 patients with ONFH-N and 43 par- ticipants without ONFH-N","Osteonecrosis of the femoral head (ONFH)","miR-206",0.6,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]

{"sheet":"mir-21","index":35,"n_rows":39,"n_cols":19,"rows_kept":39,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["Decoding the regulatory landscape of ageing in musculoskeletal engineered tissues using genome-wide DNA methylation and RNASeq","MSCs",null,"old n = 4 (65.5years±8.3SD) donors, 4 passage","age related changes in osteogenic tissue","miR-21",20.11221399234925,4.33,{"$nulls":3},"RT-qPCR",null,"mean±SEM"]
["Tumor Necrosis Factor a Suppresses the Mesenchymal Stem Cell Osteogenesis Promoter miR-21 in Estrogen Deficiency–Induced Osteoporosis","PMOP-hMSCs","bone marrow","5 postmenopausal women aged 53 to 63 years old","osteoporosis ","miR-21",0.25,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test","Spry1 decrease","up"]
["Osteogenic Differentiation of Human Amniotic Fluid Mesenchymal Stem Cells Is Determined by Epigenetic Changes","AF-MSCs","amniotic fluid","second trimester, healthy women","osteogenic differentiation 5 day","miR-21",1.25,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]
["Osteogenic Differentiation of Human Amniotic Fluid Mesenchymal Stem Cells Is Determined by Epigenetic Changes","AF-MSCs","amniotic fluid","second trimester, healthy women","osteogenic differentiation 9 day","miR-21",1.25,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]
["Osteogenic Differentiation of Human Amniotic Fluid Mesenchymal Stem Cells Is Determined by Epigenetic Changes","AF-MSCs","amniotic fluid","second trimester, healthy women","osteogenic differentiation 15 day","miR-21",1.55,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]
["Tumor Necrosis Factor a Suppresses the Mesenchymal Stem Cell Osteogenesis Promoter miR-21 in Estrogen Deficiency–Induced Osteoporosis","hMSCs","bone marrow","5 premenopausal women aged 39 to 45 years old","osteogenic differentiation + TNF-α (10 ng/mL) 10 day","miR-21",1.25,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test","Spry1 decrease","up"]
["Tumor Necrosis Factor a Suppresses the Mesenchymal Stem Cell Osteogenesis Promoter miR-21 in Estrogen Deficiency–Induced Osteoporosis","hMSCs","bone marrow","5 premenopausal women aged 39 to 45 years old","osteogenic differentiation + IL- 1β (1 ng/mL) 10 day","miR-21",1.45,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test","Spry1 decrease","up"]
["Tumor Necrosis Factor a Suppresses the Mesenchymal Stem Cell Osteogenesis Promoter miR-21 in Estrogen Deficiency–Induced Osteoporosis","hMSCs","bone marrow","5 premenopausal women aged 39 to 45 years old","osteogenic differentiation + IFN-γ (100 ng/mL) 10 day","miR-21",0.4,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test","Spry1 decrease","up"]
["Tumor Necrosis Factor a Suppresses the Mesenchymal Stem Cell Osteogenesis Promoter miR-21 in Estrogen Deficiency–Induced Osteoporosis","hMSCs","bone marrow","5 premenopausal women aged 39 to 45 years old","osteogenic differentiation 1 day","miR-21",7,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test","Spry1 decrease","up"]
["Tumor Necrosis Factor a Suppresses the Mesenchymal Stem Cell Osteogenesis Promoter miR-21 in Estrogen Deficiency–Induced Osteoporosis","hMSCs","bone marrow","5 premenopausal women aged 39 to 45 years old","osteogenic differentiation 3 day","miR-21",4,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test","Spry1 decrease","up"]
["Tumor Necrosis Factor a Suppresses the Mesenchymal Stem Cell Osteogenesis Promoter miR-21 in Estrogen Deficiency–Induced Osteoporosis","hMSCs","bone marrow","5 premenopausal women aged 39 to 45 years old","osteogenic differentiation 7 day","miR-21",10,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test","Spry1 decrease","up"]
["Tumor Necrosis Factor a Suppresses the Mesenchymal Stem Cell Osteogenesis Promoter miR-21 in Estrogen Deficiency–Induced Osteoporosis","hMSCs","bone marrow","5 premenopausal women aged 39 to 45 years old","osteogenic differentiation 10 day","miR-21",12,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test","Spry1 decrease","up"]
["Tumor Necrosis Factor a Suppresses the Mesenchymal Stem Cell Osteogenesis Promoter miR-21 in Estrogen Deficiency–Induced Osteoporosis","hMSCs","bone marrow","5 premenopausal women aged 39 to 45 years old","osteogenic differentiation 14 day","miR-21",11.5,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test","Spry1 decrease","up"]
["Tumor Necrosis Factor a Suppresses the Mesenchymal Stem Cell Osteogenesis Promoter miR-21 in Estrogen Deficiency–Induced Osteoporosis","hMSCs","bone marrow","5 premenopausal women aged 39 to 45 years old","osteogenic differentiation 21 day","miR-21",6.5,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test","Spry1 decrease","up"]
["Tumor Necrosis Factor a Suppresses the Mesenchymal Stem Cell Osteogenesis Promoter miR-21 in Estrogen Deficiency–Induced Osteoporosis","hMSCs","bone marrow","5 premenopausal women aged 39 to 45 years old","osteogenic differentiation 28 day","miR-21",6,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test","Spry1 decrease","up"]
["microRNA-21 Promotes Osteogenic Differentiation of Mesenchymal Stem Cells by the PI3K / b -Catenin Pathway","hUMSCs","umbilical cords","3 random","osteogenic differentiation 1 day","miR-21",0.7,{"$nulls":4},"RT-qPCR",null,"mean ± SD, one-way ANOVA",null,"up"]
["microRNA-21 Promotes Osteogenic Differentiation of Mesenchymal Stem Cells by the PI3K / b -Catenin Pathway","hUMSCs","umbilical cords","3 random","osteogenic differentiation 2 day","miR-21",0.6,{"$nulls":4},"RT-qPCR",null,"mean ± SD, one-way ANOVA",null,"up"]
["microRNA-21 Promotes Osteogenic Differentiation of Mesenchymal Stem Cells by the PI3K / b -Catenin Pathway","hUMSCs","umbilical cords","3 random","osteogenic differentiation 3 day","miR-21",0.8,{"$nulls":4},"RT-qPCR",null,"mean ± SD, one-way ANOVA",null,"up"]
["microRNA-21 Promotes Osteogenic Differentiation of Mesenchymal Stem Cells by the PI3K / b -Catenin Pathway","hUMSCs","umbilical cords","3 random","osteogenic differentiation 5 day","miR-21",1.3,{"$nulls":4},"RT-qPCR",null,"mean ± SD, one-way ANOVA",null,"up"]
["microRNA-21 Promotes Osteogenic Differentiation of Mesenchymal Stem Cells by the PI3K / b -Catenin Pathway","hUMSCs","umbilical cords","3 random","osteogenic differentiation 8 day","miR-21",2.1,{"$nulls":4},"RT-qPCR",null,"mean ± SD, one-way ANOVA",null,"up"]
["miR-21 Modulates the ERK–MAPK Signaling Pathway by Regulating SPRY2 Expression During Human Mesenchymal Stem Cell Differentiation","MSCs","adipose tissue","31- year-old male","osteogenic differentiation 0 day","miR-21",0.4,{"$nulls":4},"RT-qPCR",null,"One-way ANOVA, post hoc Tukey’s test","SPRY2 decrease","up"]
["miR-21 Modulates the ERK–MAPK Signaling Pathway by Regulating SPRY2 Expression During Human Mesenchymal Stem Cell Differentiation","MSCs","adipose tissue","31- year-old male","osteogenic differentiation 7 day","miR-21",0.65,{"$nulls":4},"RT-qPCR",null,"One-way ANOVA, post hoc Tukey’s test","SPRY2 decrease","up"]
["miR-21 Modulates the ERK–MAPK Signaling Pathway by Regulating SPRY2 Expression During Human Mesenchymal Stem Cell Differentiation","MSCs","adipose tissue","31- year-old male","osteogenic differentiation 14 day","miR-21",0.7,{"$nulls":4},"RT-qPCR",null,"One-way ANOVA, post hoc Tukey’s test","SPRY2 decrease","up"]
["MicroRNA-21 regulates Osteogenic Differentiation of Periodontal","PDLSC (periodontal ligament stem cells (PDLSCs))","24 healthy human first premolars ",12,"osteogenic differentiation 0 day","miR-21",1,{"$nulls":4},"RT-qPCR","down","mean ± SD","Smad5 decreased"]
["MicroRNA-21 regulates Osteogenic Differentiation of Periodontal","PDLSC (periodontal ligament stem cells (PDLSCs))","25 healthy human first premolars ",12,"osteogenic differentiation 1 day","miR-21",0,{"$nulls":4},"RT-qPCR","down","mean ± SD","Smad5 decreased"]
["MicroRNA-21 regulates Osteogenic Differentiation of Periodontal","PDLSC (periodontal ligament stem cells (PDLSCs))","26 healthy human first premolars ",12,"osteogenic differentiation 3 day","miR-21",0.2,{"$nulls":4},"RT-qPCR","down","mean ± SD","Smad5 decreased"]
["MicroRNA-21 regulates Osteogenic Differentiation of Periodontal","PDLSC (periodontal ligament stem cells (PDLSCs))","27 healthy human first premolars ",12,"osteogenic differentiation 5 day","miR-21",0,{"$nulls":4},"RT-qPCR","down","mean ± SD","Smad5 decreased"]
["MicroRNA-21 regulates Osteogenic Differentiation of Periodontal","PDLSC (periodontal ligament stem cells (PDLSCs))","28 healthy human first premolars ",12,"osteogenic differentiation 7 day","miR-21",0,{"$nulls":4},"RT-qPCR","down","mean ± SD","Smad5 decreased"]
["MicroRNA-21 regulates Osteogenic Differentiation of Periodontal","PDLSC (periodontal ligament stem cells (PDLSCs))","29 healthy human first premolars ",12,"osteogenic differentiation 10 day","miR-21",0,{"$nulls":4},"RT-qPCR","down","mean ± SD","Smad5 decreased"]
["MicroRNA-21 regulates Osteogenic Differentiation of Periodontal","PDLSC (periodontal ligament stem cells (PDLSCs))","30 healthy human first premolars ",12,"osteogenic differentiation 14 day","miR-21",0.15,{"$nulls":4},"RT-qPCR","down","mean ± SD","Smad5 decreased"]
["Differentiating Human Multipotent Mesenchymal Stromal Cells Regulate microRNAs: Prediction of microRNA Regulation by PDGF During Osteogenesis","MSC",null,"1678C (18y, African American, male), 1822A (22y, African American, male), 1832A (18y, African American, male), and 1271C (23y, African American, Female), and were designated as Donors 1, 2, 3, and 4, respectively","osteogenic differentiation 7 day","miR-21",5.5,{"$nulls":4},"RT-qPCR",null,"mean±SEM, Student t test"]
["Differentiating Human Multipotent Mesenchymal Stromal Cells Regulate microRNAs: Prediction of microRNA Regulation by PDGF During Osteogenesis","MSC",null,"1678C (18y, African American, male), 1822A (22y, African American, male), 1832A (18y, African American, male), and 1271C (23y, African American, Female), and were designated as Donors 1, 2, 3, and 4, respectively","osteogenic differentiation 7 day","miR-21",1.75,{"$nulls":4},"RT-qPCR",null,"mean±SEM, Student t test"]
["Differentiating Human Multipotent Mesenchymal Stromal Cells Regulate microRNAs: Prediction of microRNA Regulation by PDGF During Osteogenesis","pooled MSC",null,"1678C (18y, African American, male), 1822A (22y, African American, male), 1832A (18y, African American, male), and 1271C (23y, African American, Female), and were designated as Donors 1, 2, 3, and 4, respectively","treated with the PDGF pathway inhibitor AG-370 during differentiation","miR-21",3.6,{"$nulls":4},"RT-qPCR",null,"mean±SEM, Student t test"]
["Differentiating Human Multipotent Mesenchymal Stromal Cells Regulate microRNAs: Prediction of microRNA Regulation by PDGF During Osteogenesis","pooled MSC",null,"1678C (18y, African American, male), 1822A (22y, African American, male), 1832A (18y, African American, male), and 1271C (23y, African American, Female), and were designated as Donors 1, 2, 3, and 4, respectively","treated with the PDGF pathway inhibitor AG-370 during differentiation","miR-21",1.55,{"$nulls":4},"RT-qPCR",null,"mean±SEM, Student t test"]
["miR-21 synergizes with BMP9 in osteogenic differentiation by activating the BMP9 / Smad signaling pathway in murine multilineage cells","MMCs (murine multilineage cells)",{"$nulls":3},"miR-21",{"$nulls":8},"Smad7 decrease","up",null,null,"increases BMP9-induced ALP and calcium deposition in MMCs"]
["Microarc-oxidized titanium surfaces functionalized with microRNA-21-loaded chitosan/hyaluronic acid nanoparticles promote the osteogenic differentiation of human bone marrow mesenchymal stem cells","BMMSCs",null,"22-year-old female volunteer","biocompatible chitosan (CS)/ hyaluronic acid (HA) nanoparticles with miR-21","miR-21",{"$nulls":9},"up"]
["Improving the osteogenesis of human bone marrow mesenchymal stem cell sheets by microRNA-21- loaded chitosan / hyaluronic acid nanoparticles via reverse transfection","hBMMSCs","cancellous bone fragments","orthognathic patients (22–26 years of age, n=3)","cultured on miR-21-functionalized surfaces","miR-21",{"$nulls":9},"up"]
["Sox2 Suppression by miR-21 Governs Human Mesenchymal Stem Cell Properties","SS-AF-MSCs (spindle-shaped)","amniotic fluid",null,null,"miR-21",{"$nulls":9},"up"]

{"sheet":"mir-214","index":36,"n_rows":10,"n_cols":19,"rows_kept":10,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["miR‑214 promotes periodontal ligament stem cell osteoblastic differentiation by modulating Wnt/β‑catenin signaling","PDLSCs","human premolars","5 men aged 18-24 years","osteogenic differentiation","miR-214",-5,{"$nulls":4},"RT-qPCR",null,"mean ± SD, unpaired two-tailed t-test"]
["miR‑214 promotes periodontal ligament stem cell osteoblastic differentiation by modulating Wnt/β‑catenin signaling","PDLSCs","human premolars","5 men aged 18-24 years","osteogenic differentiation 0 day","miR-214",1,{"$nulls":4},"RT-qPCR",null,"mean ± SD, unpaired two-tailed t-test","β-catenin and TCF-4 decrease"]
["miR‑214 promotes periodontal ligament stem cell osteoblastic differentiation by modulating Wnt/β‑catenin signaling","PDLSCs","human premolars","5 men aged 18-24 years","osteogenic differentiation 2 day","miR-214",0.75,{"$nulls":4},"RT-qPCR",null,"mean ± SD, unpaired two-tailed t-test","β-catenin and TCF-4 decrease"]
["miR‑214 promotes periodontal ligament stem cell osteoblastic differentiation by modulating Wnt/β‑catenin signaling","PDLSCs","human premolars","5 men aged 18-24 years","osteogenic differentiation 10 day","miR-214",0.4,{"$nulls":4},"RT-qPCR",null,"mean ± SD, unpaired two-tailed t-test","β-catenin and TCF-4 decrease"]
["miR‑214 promotes periodontal ligament stem cell osteoblastic differentiation by modulating Wnt/β‑catenin signaling","PDLSCs","human premolars","5 men aged 18-24 years","osteogenic differentiation 21 day","miR-214",0.2,{"$nulls":4},"RT-qPCR",null,"mean ± SD, unpaired two-tailed t-test","β-catenin and TCF-4 decrease"]
["miR-214 targets ATF4 to inhibit bone formation",null,"bone sample",null,"osteoporotic female (70-79 y.o.)","miR-214",15,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]
["miR-214 targets ATF4 to inhibit bone formation",null,"bone sample",null,"osteoporotic female (80-89 y.o.)","miR-214",30,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]
["miR-214 targets ATF4 to inhibit bone formation",null,"bone sample",null,"osteoporotic male (70-79 y.o.)","miR-214",11,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]
["miR-214 targets ATF4 to inhibit bone formation",null,"bone sample",null,"osteoporotic male (80-89 y.o.)","miR-214",23,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]

{"sheet":"mir-21-5p","index":37,"n_rows":3,"n_cols":19,"rows_kept":3,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["MiRNA expression in the cartilage of patients with osteoarthritis",null,"femoral heads","29 OA patients","osteoarthritis","miR-21-5p",1.1,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]
["Mesenchymal stem cell-derived exosomes have altered microRNA profiles and induce osteogenic differentiation depending on the stage of differentiation","hMSCs",null,null,"exosomes from hMSC under osteogenesis 21 days vs exosomes from hMSC under osteogenesis 3 days","miR-21-5p",1.4,{"$nulls":4},"microarrays",null,"mean ± SEM, pairwise t test"]

{"sheet":"mir-218","index":38,"n_rows":21,"n_cols":19,"rows_kept":21,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["Signature of microRNA expression during osteogenic differentiation of bone marrow MSCs reveals a putative role of miR-335-5p in osteoarthritis","BM-MSCs","bone marrow from hip, patients with osteoarthrosis",null,"osteoarthrosis, osteogenic differentiation 0 day","miR-218",{"$nulls":3},18.5,null,"microarrays","ns control to osteoarthrosis"]
["Signature of microRNA expression during osteogenic differentiation of bone marrow MSCs reveals a putative role of miR-335-5p in osteoarthritis","BM-MSCs","bone marrow from hip, patients with osteoarthrosis",null,"osteoarthrosis, osteogenic differentiation 10 day","miR-218",{"$nulls":3},20,null,"microarrays","ns control to osteoarthrosis"]
["Signature of microRNA expression during osteogenic differentiation of bone marrow MSCs reveals a putative role of miR-335-5p in osteoarthritis","BM-MSCs","bone marrow from hip, patients with osteoarthrosis",null,"osteoarthrosis, osteogenic differentiation 21 day","miR-218",{"$nulls":3},22,null,"microarrays","ns control to osteoarthrosis"]
["Altered MicroRNA Expression Profile in Exosomes during Osteogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells","BMSCs","bone marrow",null,"exosomes during osteogenic differentiation","miR-218",2.288,{"$nulls":4},"microarrays"]
["Altered MicroRNA Expression Profile in Exosomes during Osteogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells","BMSCs","bone marrow",null,"exosomes during osteogenic differentiation 0,5 day","miR-218",1.4,{"$nulls":4},"RT-qPCR",null,"mean±SEM"]
["Altered MicroRNA Expression Profile in Exosomes during Osteogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells","BMSCs","bone marrow",null,"exosomes during osteogenic differentiation 1 day","miR-218",2.8,{"$nulls":4},"RT-qPCR",null,"mean±SEM"]
["Altered MicroRNA Expression Profile in Exosomes during Osteogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells","BMSCs","bone marrow",null,"exosomes during osteogenic differentiation 1,5 day","miR-218",1.6,{"$nulls":4},"RT-qPCR",null,"mean±SEM"]
["Altered MicroRNA Expression Profile in Exosomes during Osteogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells","BMSCs","bone marrow",null,"exosomes during osteogenic differentiation 2 day","miR-218",1.1,{"$nulls":4},"RT-qPCR",null,"mean±SEM"]
["Altered MicroRNA Expression Profile in Exosomes during Osteogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells","BMSCs","bone marrow",null,"exosomes during osteogenic differentiation 2,5 day","miR-218",1.4,{"$nulls":4},"RT-qPCR",null,"mean±SEM"]
["Altered MicroRNA Expression Profile in Exosomes during Osteogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells","BMSCs","bone marrow",null,"exosomes during osteogenic differentiation 3 day","miR-218",3,{"$nulls":4},"RT-qPCR",null,"mean±SEM"]
["Altered MicroRNA Expression Profile in Exosomes during Osteogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells","BMSCs","bone marrow",null,"exosomes during osteogenic differentiation 4 day","miR-218",1.4,{"$nulls":4},"RT-qPCR",null,"mean±SEM"]
["Altered MicroRNA Expression Profile in Exosomes during Osteogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells","BMSCs","bone marrow",null,"exosomes during osteogenic differentiation 5 day","miR-218",1,{"$nulls":4},"RT-qPCR",null,"mean±SEM"]
["Altered MicroRNA Expression Profile in Exosomes during Osteogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells","BMSCs","bone marrow",null,"exosomes during osteogenic differentiation 7 day","miR-218",1.4,{"$nulls":4},"RT-qPCR",null,"mean±SEM"]
["Identification and differential expression of microRNAs differentiation of human adipose-derived mesenchymal stem cells","hAMSCs","adipose tissue","healthy patients (average age 38 years)","1, 25-dihydroxyvitamin D3-induced (VD3-induced) osteogenic differentiation","miR-218",0.3,{"$nulls":4},"RT-qPCR",null,"mean±SEM, Student t test"]
["Biomimetic oyster shell – replicated topography alters the behaviour of human skeletal stem cells","SSCs (skeletal stem cells)","bone marrow",null,"osteogenic differentiation on the PCL (nacre) topographies","miR-218",1.4,{"$nulls":4},"RT-qPCR","ns","mean ± SD"]
["Biomimetic oyster shell – replicated topography alters the behaviour of human skeletal stem cells","SSCs (skeletal stem cells)","bone marrow",null,"osteogenic differentiation on the PCL (prism) topographies","miR-218",0.9,{"$nulls":4},"RT-qPCR","ns","mean ± SD"]
["MiR-590-3p regulates osteogenic differentiation of human mesenchymal stem cells by regulating APC gene","HMSCs",null,null,"osteogenic differentiation 25 day","miR-218",1.8,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]
["MicroRNA expression pro fi ling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-46","MSCs","bone marrow","3 donors","full confluence of the culture after the addition of the differentiating medium vs control","miR-218",null,"1.53153 ",{"$nulls":3},"microarrays"]
["MicroRNA expression pro fi ling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-47","MSCs","bone marrow","3 donors","full confluence of the culture after the addition of the differentiating medium vs control","miR-218",null,"1.0815",{"$nulls":3},"microarrays"]
["MicroRNA expression pro fi ling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-48","MSCs","bone marrow","3 donors","full confluence of the culture after the addition of the differentiating medium vs control","miR-218",null,"2.22981",{"$nulls":3},"microarrays"]

{"sheet":"mir-22","index":39,"n_rows":12,"n_cols":19,"rows_kept":12,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["Evidence for Altered Canonical Wnt Signaling in the Trabecular Bone of Elderly Postmenopausal Women with Fragility Femoral Fracture","bone sample","intertrochanteric region of the femur","54 female patients",null,"miR-22",{"$nulls":3},"ns",null,"RT-qPCR"]
["Global miRNA expression and correlation with mRNA levels in primary human bone cells","HOBs (primary human osteoblasts)","trabecular bone",null,"male","miR-22",1.1,{"$nulls":4},"RT-qPCR",null,"Student’s t-test"]
["Global miRNA expression and correlation with mRNA levels in primary human bone cells","HOBs (primary human osteoblasts)","trabecular bone",null,"female","miR-22",1,{"$nulls":4},"RT-qPCR",null,"Student’s t-test"]
["MicroRNAs miR-26a, miR-26b, and miR-29b accelerate osteogenic differentiation of unrestricted somatic stem cells from human cord blood","SA5/73","USSC, human cord blood",null,"7 day after osteogenic stimuli","miR-22",4,{"$nulls":4},"microarrays",null,null,"CDK6 (analysed in HEK293T)"]
["MicroRNAs miR-26a, miR-26b, and miR-29b accelerate osteogenic differentiation of unrestricted somatic stem cells from human cord blood","SA8/25","USSC, human cord blood",null,"7 day after osteogenic stimuli","miR-22",12,{"$nulls":4},"microarrays",null,null,"CDK6 (analysed in HEK293T)"]
["MiR-590-3p regulates osteogenic differentiation of human mesenchymal stem cells by regulating APC gene","HMSCs",null,null,"osteogenic differentiation 25 day","miR-22",2.1,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]
["Differentiating Human Multipotent Mesenchymal Stromal Cells Regulate microRNAs: Prediction of microRNA Regulation by PDGF During Osteogenesis","MSC",null,"1678C (18y, African American, male), 1822A (22y, African American, male), 1832A (18y, African American, male), and 1271C (23y, African American, Female), and were designated as Donors 1, 2, 3, and 4, respectively","osteogenic differentiation 7 day","miR-22",4,{"$nulls":4},"RT-qPCR",null,"mean±SEM, Student t test"]
["Differentiating Human Multipotent Mesenchymal Stromal Cells Regulate microRNAs: Prediction of microRNA Regulation by PDGF During Osteogenesis","MSC",null,"1678C (18y, African American, male), 1822A (22y, African American, male), 1832A (18y, African American, male), and 1271C (23y, African American, Female), and were designated as Donors 1, 2, 3, and 4, respectively","osteogenic differentiation 7 day","miR-22",3,{"$nulls":4},"RT-qPCR",null,"mean±SEM, Student t test"]
["MicroRNA-138 regulates osteogenic differentiation of human stromal (mesenchymal) stem cells in vivo","hMSCs","telomerase immortalized bone marrow",null,"osteogenic differentiation 10 day","miR-22 ",1.4240501955970717,0.51,{"$nulls":3},"microarrays",null,"mean ± SD"]
["Differentiating Human Multipotent Mesenchymal Stromal Cells Regulate microRNAs: Prediction of microRNA Regulation by PDGF During Osteogenesis","pooled MSC",null,"1678C (18y, African American, male), 1822A (22y, African American, male), 1832A (18y, African American, male), and 1271C (23y, African American, Female), and were designated as Donors 1, 2, 3, and 4, respectively","treated with the PDGF pathway inhibitor AG-370 during differentiation","miR-22",3.5,{"$nulls":4},"RT-qPCR",null,"mean±SEM, Student t test"]
["Differentiating Human Multipotent Mesenchymal Stromal Cells Regulate microRNAs: Prediction of microRNA Regulation by PDGF During Osteogenesis","pooled MSC",null,"1678C (18y, African American, male), 1822A (22y, African American, male), 1832A (18y, African American, male), and 1271C (23y, African American, Female), and were designated as Donors 1, 2, 3, and 4, respectively","treated with the PDGF pathway inhibitor AG-370 during differentiation","miR-22",2.8,{"$nulls":4},"RT-qPCR",null,"mean±SEM, Student t test"]

{"sheet":"mir-221","index":40,"n_rows":5,"n_cols":19,"rows_kept":5,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["Biochemical and Biophysical Research Communications PDGF-regulated miRNA-138 inhibits the osteogenic differentiation of mesenchymal stem cells","hMSCs","Telomerase-immortalized bone marrow-derived",null,"osteogenesis + PDGF treatment 15 day","miR-221",1.8,{"$nulls":4},"RT-qPCR",null,"mean+SEM"]
["Altered MicroRNA Expression Profile in Exosomes during Osteogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells","BMSCs","bone marrow",null,"exosomes during osteogenic differentiation","miR-221","0.172",{"$nulls":4},"microarrays"]
["MicroRNA-221 is involved in the regulation of osteoporosis through regulates RUNX2 protein expression and osteoblast differentiation",null,"bone samples","12 postmenopausal women with osteoporosis","osteoporosis","miR-221",0.25,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]
["MicroRNA-221 is involved in the regulation of osteoporosis through regulates RUNX2 protein expression and osteoblast differentiation",null,"bone samples","12 postmenopausal women who were diagnosed as osteoarthritis in the absence of osteoporosis","control","miR-221",2.5,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]

{"sheet":"mir-222","index":41,"n_rows":9,"n_cols":19,"rows_kept":9,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["Signature of microRNA expression during osteogenic differentiation of bone marrow MSCs reveals a putative role of miR-335-5p in osteoarthritis","BM-MSCs","bone marrow from hip, patients with osteoarthrosis",null,"osteoarthrosis, osteogenic differentiation 0 day","miR-222",{"$nulls":3},10.5,null,"microarrays","ns control to osteoarthrosis"]
["Signature of microRNA expression during osteogenic differentiation of bone marrow MSCs reveals a putative role of miR-335-5p in osteoarthritis","BM-MSCs","bone marrow from hip, patients with osteoarthrosis",null,"osteoarthrosis, osteogenic differentiation 10 day","miR-222",{"$nulls":3},10.5,null,"microarrays","ns control to osteoarthrosis"]
["Signature of microRNA expression during osteogenic differentiation of bone marrow MSCs reveals a putative role of miR-335-5p in osteoarthritis","BM-MSCs","bone marrow from hip, patients with osteoarthrosis",null,"osteoarthrosis, osteogenic differentiation 21 day","miR-222",{"$nulls":3},12,null,"microarrays","ns control to osteoarthrosis"]
["Inhibition of microRNA-222 expression accelerates bone healing with enhancement of osteogenesis , chondrogenesis , and angiogenesis in a rat refractory fracture model","hBMSCs","bone marrow",null,"osteogenic differentiation 3 day","miR-222",0.7,{"$nulls":4},"RT-qPCR",null,"one-way ANOVA followed by the Tukeye-Kramer test",null,"down"]
["Inhibition of microRNA-222 expression accelerates bone healing with enhancement of osteogenesis , chondrogenesis , and angiogenesis in a rat refractory fracture model","hBMSCs","bone marrow",null,"osteogenic differentiation 7 day","miR-222",0.45,{"$nulls":4},"RT-qPCR",null,"one-way ANOVA followed by the Tukeye-Kramer test",null,"down"]
["Inhibition of microRNA-222 expression accelerates bone healing with enhancement of osteogenesis , chondrogenesis , and angiogenesis in a rat refractory fracture model","hBMSCs","bone marrow",null,"osteogenic differentiation 14 day","miR-222",0.35,{"$nulls":4},"RT-qPCR",null,"one-way ANOVA followed by the Tukeye-Kramer test",null,"down"]
["MicroRNA-138 regulates osteogenic differentiation of human stromal (mesenchymal) stem cells in vivo","hMSCs","telomerase immortalized bone marrow",null,"osteogenic differentiation 10 day","miR-222",0.6461764153187461,-0.63,{"$nulls":3},"RT-qPCR",null,"mean ± SD"]
["MicroRNA-138 regulates osteogenic differentiation of human stromal (mesenchymal) stem cells in vivo","hMSCs","telomerase immortalized bone marrow",null,"osteogenic differentiation 10 day","miR-222",0.6070974421975235,-0.72,{"$nulls":3},"microarrays",null,"mean ± SD"]

{"sheet":"mir-23a","index":42,"n_rows":10,"n_cols":19,"rows_kept":10,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["MicroRNA-23a inhibits osteogenic differentiation of human bone marrow-derived mesenchymal stem cells by targeting LRP5","hBMSCs","bone marrow","three healthy donors","osteogenic differentiation 3 day","miR-23a",0.5,{"$nulls":4},"RT-qPCR",null,"mean ± SD, two-tailed Student t test"]
["MicroRNA-23a inhibits osteogenic differentiation of human bone marrow-derived mesenchymal stem cells by targeting LRP6","hBMSCs","bone marrow","three healthy donors","osteogenic differentiation 6 day","miR-23a",0.45,{"$nulls":4},"RT-qPCR",null,"mean ± SD, two-tailed Student t test"]
["MicroRNA-23a inhibits osteogenic differentiation of human bone marrow-derived mesenchymal stem cells by targeting LRP7","hBMSCs","bone marrow","three healthy donors","osteogenic differentiation 9 day","miR-23a",0.65,{"$nulls":4},"RT-qPCR",null,"mean ± SD, two-tailed Student t test"]
["MicroRNA-23a inhibits osteogenic differentiation of human bone marrow-derived mesenchymal stem cells by targeting LRP8","hBMSCs","bone marrow","three healthy donors","osteogenic differentiation 12 day","miR-23a",0.9,{"$nulls":4},"RT-qPCR",null,"mean ± SD, two-tailed Student t test"]
["The effects of hedgehog on RNA binding protein Msi1 during the osteogenic differentiation of human cord blood-derived mesenchymal stem cells","hUCB-MSCs","umbilical cord blood",null,"osteogenic differentiation 21 day ","miR-23a",1.2,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]
["The effects of hedgehog on RNA binding protein Msi1 during the osteogenic differentiation of human cord blood-derived mesenchymal stem cells","hUCB-MSCs","umbilical cord blood",null,"osteogenic differentiation 21 day + purmorphamine (activates the Hh pathway)","miR-23a",0.9,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]
["MicroRNA expression pro fi ling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-73","MSCs","bone marrow","3 donors","full confluence of the culture after the addition of the differentiating medium vs control","miR-23a",null,"0.73078  ",{"$nulls":3},"microarrays"]
["MicroRNA expression pro fi ling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-74","MSCs","bone marrow","3 donors","full confluence of the culture after the addition of the differentiating medium vs control","miR-23a",null,"1.24748",{"$nulls":3},"microarrays"]
["MicroRNA expression pro fi ling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-75","MSCs","bone marrow","3 donors","full confluence of the culture after the addition of the differentiating medium vs control","miR-23a",null,"1.24828",{"$nulls":3},"microarrays"]

{"sheet":"mir-23b","index":43,"n_rows":16,"n_cols":19,"rows_kept":16,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["The effects of hedgehog on RNA binding protein Msi1 during the osteogenic differentiation of human cord blood-derived mesenchymal stem cells","hUCB-MSCs","umbilical cord blood",null,"osteogenic differentiation 21 day ","miR-23b",2.1,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]
["The effects of hedgehog on RNA binding protein Msi1 during the osteogenic differentiation of human cord blood-derived mesenchymal stem cells","hUCB-MSCs","umbilical cord blood",null,"osteogenic differentiation 21 day + purmorphamine (activates the Hh pathway)","miR-23b",2.1,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]
["MicroRNA expression pro fi ling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-79","MSCs","bone marrow","3 donors","full confluence of the culture after the addition of the differentiating medium vs control","miR-23b",null,"0.426573  ",{"$nulls":3},"microarrays"]
["MicroRNA expression pro fi ling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-80","MSCs","bone marrow","3 donors","full confluence of the culture after the addition of the differentiating medium vs control","miR-23b",null,"0.967372",{"$nulls":3},"microarrays"]
["MicroRNA expression pro fi ling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-81","MSCs","bone marrow","3 donors","full confluence of the culture after the addition of the differentiating medium vs control","miR-23b",null,"0.785528",{"$nulls":3},"microarrays"]
["MicroRNA expression pro fi ling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-146","MSCs","bone marrow","3 donors","control","miR-23b",0.04,{"$nulls":4},"RT-qPCR",null,"mean+SEM"]
["MicroRNA expression pro fi ling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-147","MSCs","bone marrow","3 donors","full confluence of the culture after the addition of the differentiating medium","miR-23b",0.2,{"$nulls":4},"RT-qPCR",null,"mean+SEM"]
["MicroRNA expression pro fi ling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-148","MSCs","bone marrow","3 donors","mineral nodule deposition one week after the addition of the mineralization medium","miR-23b",0.23,{"$nulls":4},"RT-qPCR",null,"mean+SEM"]
["Altered function in cartilage derived mesenchymal stem cell leads to OA-related cartilage erosion","CMSC","medial and lateral condyles","12 patients (4 males, 8 females, median age 67.8 years, range 47-79 years)","osteoarthritis","miR-23b",2.123523390523728,1.08646,{"$nulls":3},"microarrays"]
["Altered function in cartilage derived mesenchymal stem cell leads to OA-related cartilage erosion","CMSC","medial and lateral condyles","12 patients (4 males, 8 females, median age 67.8 years, range 47-79 years)","osteoarthritis","miR-23b",1.2,{"$nulls":4},"RT-qPCR",null,"mean+SEM"]
["Altered function in cartilage derived mesenchymal stem cell leads to OA-related cartilage erosion","CMSC","medial and lateral condyles","12 patients (4 males, 8 females, median age 67.8 years, range 47-79 years)","osteoarthritis","miR-23b",1.25,{"$nulls":4},"RT-qPCR",null,"mean+SEM"]
["miR-214 targets ATF4 to inhibit bone formation",null,"bone sample",null,"osteoporotic female (70-79 y.o.)","miR-23b",9.5,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]
["miR-214 targets ATF4 to inhibit bone formation",null,"bone sample",null,"osteoporotic female (80-89 y.o.)","miR-23b",11,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]
["miR-214 targets ATF4 to inhibit bone formation",null,"bone sample",null,"osteoporotic male (70-79 y.o.)","miR-23b",7,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]
["miR-214 targets ATF4 to inhibit bone formation",null,"bone sample",null,"osteoporotic male (80-89 y.o.)","miR-23b",9,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]

{"sheet":"mir-26a","index":44,"n_rows":10,"n_cols":19,"rows_kept":10,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["A regulatory loop containing miR- 26a, GSK3β and C/EBPα regulates the osteogenesis of human adipose-derived mesenchymal stem cells","hASCs","fat tissue",null,"osteogenic differentiation 3 day","miR-26a",1.9,{"$nulls":4},"RT-qPCR",null,"mean ± SD","GSK3β decrease"]
["A regulatory loop containing miR- 26a, GSK3β and C/EBPα regulates the osteogenesis of human adipose-derived mesenchymal stem cells","hASCs","fat tissue",null,"osteogenic differentiation 7 day","miR-26a",4,{"$nulls":4},"RT-qPCR",null,"mean ± SD","GSK3β decrease"]
["A regulatory loop containing miR- 26a, GSK3β and C/EBPα regulates the osteogenesis of human adipose-derived mesenchymal stem cells","hASCs","fat tissue",null,"osteogenic differentiation 14 day","miR-26a",6.7,{"$nulls":4},"RT-qPCR",null,"mean ± SD","GSK3β decrease"]
["MicroRNAs miR-26a, miR-26b, and miR-29b accelerate osteogenic differentiation of unrestricted somatic stem cells from human cord blood","SA5/73","USSC, human cord blood",null,"7 day after osteogenic stimuli","miR-26a",4,{"$nulls":4},"microarrays",null,null,"CDK6, CTNNBIP1 (ICAT), SMAD1, TOB1 (analysed in HEK293T)"]
["MicroRNAs miR-26a, miR-26b, and miR-29b accelerate osteogenic differentiation of unrestricted somatic stem cells from human cord blood","SA8/25","USSC, human cord blood",null,"7 day after osteogenic stimuli","miR-26a",6,{"$nulls":4},"microarrays",null,null,"CDK6, CTNNBIP1 (ICAT), Smad1, TOB1 (analysed in HEK293T)"]
["MicroRNA-138 regulates osteogenic differentiation of human stromal (mesenchymal) stem cells in vivo","hMSCs","telomerase immortalized bone marrow",null,"osteogenic differentiation 10 day","miR-26a",3.410539567071827,1.77,{"$nulls":3},"RT-qPCR",null,"mean ± SD"]
["Differentiating Human Multipotent Mesenchymal Stromal Cells Regulate microRNAs: Prediction of microRNA Regulation by PDGF During Osteogenesis","MSC",null,"1678C (18y, African American, male), 1822A (22y, African American, male), 1832A (18y, African American, male), and 1271C (23y, African American, Female), and were designated as Donors 1, 2, 3, and 4, respectively","osteogenic differentiation 7 day","miR-26a",4.5,{"$nulls":4},"RT-qPCR",null,"mean±SEM, Student t test"]
["Differentiating Human Multipotent Mesenchymal Stromal Cells Regulate microRNAs: Prediction of microRNA Regulation by PDGF During Osteogenesis","MSC",null,"1678C (18y, African American, male), 1822A (22y, African American, male), 1832A (18y, African American, male), and 1271C (23y, African American, Female), and were designated as Donors 1, 2, 3, and 4, respectively","osteogenic differentiation 7 day","miR-26a",2.3,{"$nulls":4},"RT-qPCR",null,"mean±SEM, Student t test"]
["MicroRNA-138 regulates osteogenic differentiation of human stromal (mesenchymal) stem cells in vivo","hMSCs","telomerase immortalized bone marrow",null,"osteogenic differentiation 10 day","miR-26a ",2,1,{"$nulls":3},"microarrays",null,"mean ± SD"]

{"sheet":"mir-27a","index":45,"n_rows":12,"n_cols":19,"rows_kept":12,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["Bone marrow stromal / stem cell- derived extracellular vesicles regulate osteoblast activity and differentiation in vitro and promote bone regeneration in vivo","BMSCs",null,"2 donors","miR-27a treatment","miR-27a",{"$nulls":9},"up"]
["MiR-1827 inhibits osteogenic differentiation by targeting IGF1 in MSMSCs","BMSSCs",null,null,"osteogenic differentiation 3 day","miR-27a",0.6,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]
["MiR-27a is Essential for the Shift from Osteogenic Differentiation to Adipogenic Differentiation of Mesenchymal Stem Cells in Postmenopausal Osteoporosis","hMSCs",null,"3 osteoporotic patients, 5 passage","osteogenic differentiation 1 week","miR-27a",5,{"$nulls":6},"mean+SEM","Mef2c decrease","down"]
["MiR-27a is Essential for the Shift from Osteogenic Differentiation to Adipogenic Differentiation of Mesenchymal Stem Cells in Postmenopausal Osteoporosis","hMSCs",null,"3 osteoporotic patients, 5 passage","osteogenic differentiation 2 week","miR-27a",28,{"$nulls":6},"mean+SEM","Mef2c decrease","down"]
["MiR-27a is Essential for the Shift from Osteogenic Differentiation to Adipogenic Differentiation of Mesenchymal Stem Cells in Postmenopausal Osteoporosis","hMSCs",null,"3 osteoporotic patients, 5 passage","osteogenic differentiation 3 week","miR-27a",100,{"$nulls":6},"mean+SEM","Mef2c decrease","down"]
["MiR-1827 inhibits osteogenic differentiation by targeting IGF1 in MSMSCs","MSMSCs","maxillary sinus membrane stem cells","16 individuals aged 18–29 years ","osteogenic differentiation 3 day","miR-27a",0.4,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]
["Differentiating Human Multipotent Mesenchymal Stromal Cells Regulate microRNAs: Prediction of microRNA Regulation by PDGF During Osteogenesis","MSC",null,"1678C (18y, African American, male), 1822A (22y, African American, male), 1832A (18y, African American, male), and 1271C (23y, African American, Female), and were designated as Donors 1, 2, 3, and 4, respectively","osteogenic differentiation 7 day","miR-27a",3,{"$nulls":4},"RT-qPCR",null,"mean±SEM, Student t test"]
["Differentiating Human Multipotent Mesenchymal Stromal Cells Regulate microRNAs: Prediction of microRNA Regulation by PDGF During Osteogenesis","MSC",null,"1678C (18y, African American, male), 1822A (22y, African American, male), 1832A (18y, African American, male), and 1271C (23y, African American, Female), and were designated as Donors 1, 2, 3, and 4, respectively","osteogenic differentiation 7 day","miR-27a",2.15,{"$nulls":4},"RT-qPCR",null,"mean±SEM, Student t test"]
["Differentiating Human Multipotent Mesenchymal Stromal Cells Regulate microRNAs: Prediction of microRNA Regulation by PDGF During Osteogenesis","pooled MSC",null,"1678C (18y, African American, male), 1822A (22y, African American, male), 1832A (18y, African American, male), and 1271C (23y, African American, Female), and were designated as Donors 1, 2, 3, and 4, respectively","treated with the PDGF pathway inhibitor AG-370 during differentiation","miR-27a",2.4,{"$nulls":4},"RT-qPCR",null,"mean±SEM, Student t test"]
["Differentiating Human Multipotent Mesenchymal Stromal Cells Regulate microRNAs: Prediction of microRNA Regulation by PDGF During Osteogenesis","pooled MSC",null,"1678C (18y, African American, male), 1822A (22y, African American, male), 1832A (18y, African American, male), and 1271C (23y, African American, Female), and were designated as Donors 1, 2, 3, and 4, respectively","treated with the PDGF pathway inhibitor AG-370 during differentiation","miR-27a",2,{"$nulls":4},"RT-qPCR",null,"mean±SEM, Student t test"]
["MiR-27a is Essential for the Shift from Osteogenic Differentiation to Adipogenic Differentiation of Mesenchymal Stem Cells in Postmenopausal Osteoporosis",null,"serum",null,"osteoporosis","miR-27a",103.91169,{"$nulls":4},"microarrays"]

{"sheet":"mir-27b","index":46,"n_rows":5,"n_cols":19,"rows_kept":5,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["MiRNA expression in the cartilage of patients with osteoarthritis",null,"femoral heads","29 OA patients","osteoarthritis","miR-27b-3p",1.4,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]
["Osteogenic Differentiation of MSC through Calcium Signaling Activation : Transcriptomics and Functional Analysis","hMSCs","bone marrow",null,"calcium-based scaffolds induced osteogenic differentiation 10 day vs 5 day","miR-27b-3p",null,"-1.05537718586587",{"$nulls":3},"microarrays",null,"mean±SEM"]
["Mesenchymal stem cell-derived exosomes have altered microRNA profiles and induce osteogenic differentiation depending on the stage of differentiation","hMSCs",null,null,"exosomes from hMSC under osteogenesis 21 days","miR-27b-3p",{"v":1.7,"d":"1.70"},{"$nulls":4},"microarrays",null,"mean ± SEM, pairwise t test"]
["Mesenchymal stem cell-derived exosomes have altered microRNA profiles and induce osteogenic differentiation depending on the stage of differentiation","hMSCs",null,null,"exosomes from hMSC under osteogenesis 21 days vs exosomes from hMSC under osteogenesis 3 days","miR-27b-3p",1.6,{"$nulls":4},"microarrays",null,"mean ± SEM, pairwise t test"]

{"sheet":"mir-29a","index":47,"n_rows":7,"n_cols":19,"rows_kept":7,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["Evidence for Altered Canonical Wnt Signaling in the Trabecular Bone of Elderly Postmenopausal Women with Fragility Femoral Fracture","bone sample","intertrochanteric region of the femur","54 female patients",null,"miR-29a",{"$nulls":3},"ns",null,"RT-qPCR"]
["MicroRNA-138 regulates osteogenic differentiation of human stromal (mesenchymal) stem cells in vivo","hMSCs","telomerase immortalized bone marrow",null,"osteogenic differentiation 10 day","miR-29a",null,"0.56 ± 0.02 ",{"$nulls":3},"microarrays",null,"mean ± SD"]
["Differentiating Human Multipotent Mesenchymal Stromal Cells Regulate microRNAs: Prediction of microRNA Regulation by PDGF During Osteogenesis","MSC",null,"1678C (18y, African American, male), 1822A (22y, African American, male), 1832A (18y, African American, male), and 1271C (23y, African American, Female), and were designated as Donors 1, 2, 3, and 4, respectively","osteogenic differentiation 7 day","miR-29a",2.5,{"$nulls":4},"RT-qPCR",null,"mean±SEM, Student t test"]
["Differentiating Human Multipotent Mesenchymal Stromal Cells Regulate microRNAs: Prediction of microRNA Regulation by PDGF During Osteogenesis","MSC",null,"1678C (18y, African American, male), 1822A (22y, African American, male), 1832A (18y, African American, male), and 1271C (23y, African American, Female), and were designated as Donors 1, 2, 3, and 4, respectively","osteogenic differentiation 7 day","miR-29a",1.5,{"$nulls":4},"RT-qPCR",null,"mean±SEM, Student t test"]
["Differentiating Human Multipotent Mesenchymal Stromal Cells Regulate microRNAs: Prediction of microRNA Regulation by PDGF During Osteogenesis","pooled MSC",null,"1678C (18y, African American, male), 1822A (22y, African American, male), 1832A (18y, African American, male), and 1271C (23y, African American, Female), and were designated as Donors 1, 2, 3, and 4, respectively","treated with the PDGF pathway inhibitor AG-370 during differentiation","miR-29a",2.5,{"$nulls":4},"RT-qPCR",null,"mean±SEM, Student t test"]
["Differentiating Human Multipotent Mesenchymal Stromal Cells Regulate microRNAs: Prediction of microRNA Regulation by PDGF During Osteogenesis","pooled MSC",null,"1678C (18y, African American, male), 1822A (22y, African American, male), 1832A (18y, African American, male), and 1271C (23y, African American, Female), and were designated as Donors 1, 2, 3, and 4, respectively","treated with the PDGF pathway inhibitor AG-370 during differentiation","miR-29a",1.25,{"$nulls":4},"RT-qPCR",null,"mean±SEM, Student t test"]

{"sheet":"mir-29b","index":48,"n_rows":32,"n_cols":19,"rows_kept":32,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["Global miRNA expression and correlation with mRNA levels in primary human bone cells","HOBs (primary human osteoblasts)","trabecular bone",null,"male","miR-29b",1.1,{"$nulls":4},"RT-qPCR",null,"Student’s t-test","Col1A1, SPARC decrease"]
["Global miRNA expression and correlation with mRNA levels in primary human bone cells","HOBs (primary human osteoblasts)","trabecular bone",null,"female","miR-29b",2.3,{"$nulls":4},"RT-qPCR",null,"Student’s t-test","Col1A1, SPARC decrease"]
["COL1A1 and miR-29b show lower expression levels during osteoblast differentiation of bone marrow stromal cells from Osteogenesis Imperfecta patients","mononuclear cell fractions","bone marrow","Osteogenesis Imperfecta type I","osteogenic differentiation 0 day","miR-29b",0.2,{"$nulls":4},"RT-qPCR",null,"mean ± SD",null,"non-requirement"]
["COL1A1 and miR-29b show lower expression levels during osteoblast differentiation of bone marrow stromal cells from Osteogenesis Imperfecta patients","mononuclear cell fractions","bone marrow","Osteogenesis Imperfecta type I","osteogenic differentiation 1 day","miR-29b",0.2,{"$nulls":4},"RT-qPCR",null,"mean ± SD",null,"non-requirement"]
["COL1A1 and miR-29b show lower expression levels during osteoblast differentiation of bone marrow stromal cells from Osteogenesis Imperfecta patients","mononuclear cell fractions","bone marrow","Osteogenesis Imperfecta type I","osteogenic differentiation 2 day","miR-29b",0.3,{"$nulls":4},"RT-qPCR",null,"mean ± SD",null,"non-requirement"]
["COL1A1 and miR-29b show lower expression levels during osteoblast differentiation of bone marrow stromal cells from Osteogenesis Imperfecta patients","mononuclear cell fractions","bone marrow","Osteogenesis Imperfecta type I","osteogenic differentiation 7 day","miR-29b",0.2,{"$nulls":4},"RT-qPCR",null,"mean ± SD",null,"non-requirement"]
["COL1A1 and miR-29b show lower expression levels during osteoblast differentiation of bone marrow stromal cells from Osteogenesis Imperfecta patients","mononuclear cell fractions","bone marrow","Osteogenesis Imperfecta type I","osteogenic differentiation 12 day","miR-29b",0.5,{"$nulls":4},"RT-qPCR",null,"mean ± SD",null,"non-requirement"]
["COL1A1 and miR-29b show lower expression levels during osteoblast differentiation of bone marrow stromal cells from Osteogenesis Imperfecta patients","mononuclear cell fractions","bone marrow","Osteogenesis Imperfecta type I","osteogenic differentiation 17 day","miR-29b",1.5,{"$nulls":4},"RT-qPCR",null,"mean ± SD",null,"non-requirement"]
["COL1A1 and miR-29b show lower expression levels during osteoblast differentiation of bone marrow stromal cells from Osteogenesis Imperfecta patients","mononuclear cell fractions","bone marrow","Osteogenesis Imperfecta type I","osteogenic differentiation 21 day","miR-29b",0,{"$nulls":4},"RT-qPCR",null,"mean ± SD",null,"non-requirement"]
["COL1A1 and miR-29b show lower expression levels during osteoblast differentiation of bone marrow stromal cells from Osteogenesis Imperfecta patients","mononuclear cell fractions","bone marrow","Osteogenesis Imperfecta type III","osteogenic differentiation 0 day","miR-29b",0.1,{"$nulls":4},"RT-qPCR",null,"mean ± SD",null,"non-requirement"]
["COL1A1 and miR-29b show lower expression levels during osteoblast differentiation of bone marrow stromal cells from Osteogenesis Imperfecta patients","mononuclear cell fractions","bone marrow","Osteogenesis Imperfecta type III","osteogenic differentiation 1 day","miR-29b",0.1,{"$nulls":4},"RT-qPCR",null,"mean ± SD",null,"non-requirement"]
["COL1A1 and miR-29b show lower expression levels during osteoblast differentiation of bone marrow stromal cells from Osteogenesis Imperfecta patients","mononuclear cell fractions","bone marrow","Osteogenesis Imperfecta type III","osteogenic differentiation 2 day","miR-29b",0.1,{"$nulls":4},"RT-qPCR",null,"mean ± SD",null,"non-requirement"]
["COL1A1 and miR-29b show lower expression levels during osteoblast differentiation of bone marrow stromal cells from Osteogenesis Imperfecta patients","mononuclear cell fractions","bone marrow","Osteogenesis Imperfecta type III","osteogenic differentiation 7 day","miR-29b",0.1,{"$nulls":4},"RT-qPCR",null,"mean ± SD",null,"non-requirement"]
["COL1A1 and miR-29b show lower expression levels during osteoblast differentiation of bone marrow stromal cells from Osteogenesis Imperfecta patients","mononuclear cell fractions","bone marrow","Osteogenesis Imperfecta type III","osteogenic differentiation 12 day","miR-29b",0.5,{"$nulls":4},"RT-qPCR",null,"mean ± SD",null,"non-requirement"]
["COL1A1 and miR-29b show lower expression levels during osteoblast differentiation of bone marrow stromal cells from Osteogenesis Imperfecta patients","mononuclear cell fractions","bone marrow","Osteogenesis Imperfecta type III","osteogenic differentiation 17 day","miR-29b",1.2,{"$nulls":4},"RT-qPCR",null,"mean ± SD",null,"non-requirement"]
["COL1A1 and miR-29b show lower expression levels during osteoblast differentiation of bone marrow stromal cells from Osteogenesis Imperfecta patients","mononuclear cell fractions","bone marrow","Osteogenesis Imperfecta type III","osteogenic differentiation 21 day","miR-29b",0,{"$nulls":4},"RT-qPCR",null,"mean ± SD",null,"non-requirement"]
["COL1A1 and miR-29b show lower expression levels during osteoblast differentiation of bone marrow stromal cells from Osteogenesis Imperfecta patients","mononuclear cell fractions","bone marrow","control 3 donors","osteogenic differentiation 0 day","miR-29b",2,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]
["COL1A1 and miR-29b show lower expression levels during osteoblast differentiation of bone marrow stromal cells from Osteogenesis Imperfecta patients","mononuclear cell fractions","bone marrow","control 3 donors","osteogenic differentiation 1 day","miR-29b",1.8,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]
["COL1A1 and miR-29b show lower expression levels during osteoblast differentiation of bone marrow stromal cells from Osteogenesis Imperfecta patients","mononuclear cell fractions","bone marrow","control 3 donors","osteogenic differentiation 2 day","miR-29b",1.5,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]
["COL1A1 and miR-29b show lower expression levels during osteoblast differentiation of bone marrow stromal cells from Osteogenesis Imperfecta patients","mononuclear cell fractions","bone marrow","control 3 donors","osteogenic differentiation 7 day","miR-29b",2,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]
["COL1A1 and miR-29b show lower expression levels during osteoblast differentiation of bone marrow stromal cells from Osteogenesis Imperfecta patients","mononuclear cell fractions","bone marrow","control 3 donors","osteogenic differentiation 12 day","miR-29b",1,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]
["COL1A1 and miR-29b show lower expression levels during osteoblast differentiation of bone marrow stromal cells from Osteogenesis Imperfecta patients","mononuclear cell fractions","bone marrow","control 3 donors","osteogenic differentiation 17 day","miR-29b",2,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]
["COL1A1 and miR-29b show lower expression levels during osteoblast differentiation of bone marrow stromal cells from Osteogenesis Imperfecta patients","mononuclear cell fractions","bone marrow","control 3 donors","osteogenic differentiation 21 day","miR-29b",2.4,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]
["MicroRNAs miR-26a, miR-26b, and miR-29b accelerate osteogenic differentiation of unrestricted somatic stem cells from human cord blood","SA5/73","USSC, human cord blood",null,"7 day after osteogenic stimuli","miR-29b",4,{"$nulls":4},"microarrays",null,null,"CDK6, CTNNBIP1 (ICAT), HDAC4 (analysed in HEK293T)"]
["MicroRNAs miR-26a, miR-26b, and miR-29b accelerate osteogenic differentiation of unrestricted somatic stem cells from human cord blood","SA8/25","USSC, human cord blood",null,"7 day after osteogenic stimuli","miR-29b",10,{"$nulls":4},"microarrays",null,null,"CDK6, CTNNBIP1 (ICAT), HDAC4 (analysed in HEK293T)"]
["COL1A1 and miR-29b show lower expression levels during osteoblast differentiation of bone marrow stromal cells from Osteogenesis Imperfecta patients","mononuclear cell fractions","bone marrow","Osteogenesis Imperfecta-5 (Bruck Syndrome)","osteogenic differentiation 1 day","miR-29b",0,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]
["COL1A1 and miR-29b show lower expression levels during osteoblast differentiation of bone marrow stromal cells from Osteogenesis Imperfecta patients","mononuclear cell fractions","bone marrow","Osteogenesis Imperfecta-5 (Bruck Syndrome)","osteogenic differentiation 2 day","miR-29b",1,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]
["COL1A1 and miR-29b show lower expression levels during osteoblast differentiation of bone marrow stromal cells from Osteogenesis Imperfecta patients","mononuclear cell fractions","bone marrow","Osteogenesis Imperfecta-5 (Bruck Syndrome)","osteogenic differentiation 7 day","miR-29b",1.5,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]
["COL1A1 and miR-29b show lower expression levels during osteoblast differentiation of bone marrow stromal cells from Osteogenesis Imperfecta patients","mononuclear cell fractions","bone marrow","Osteogenesis Imperfecta-5 (Bruck Syndrome)","osteogenic differentiation 12 day","miR-29b",5.2,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]
["COL1A1 and miR-29b show lower expression levels during osteoblast differentiation of bone marrow stromal cells from Osteogenesis Imperfecta patients","mononuclear cell fractions","bone marrow","Osteogenesis Imperfecta-5 (Bruck Syndrome)","osteogenic differentiation 17 day","miR-29b",3.3,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]
["COL1A1 and miR-29b show lower expression levels during osteoblast differentiation of bone marrow stromal cells from Osteogenesis Imperfecta patients","mononuclear cell fractions","bone marrow","Osteogenesis Imperfecta-5 (Bruck Syndrome)","osteogenic differentiation 21 day","miR-29b",3.6,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]

{"sheet":"mir-30a","index":49,"n_rows":9,"n_cols":19,"rows_kept":9,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["MiR-708 promotes steroid- induced osteonecrosis of femoral head , suppresses osteogenic differentiation by targeting SMAD3","hMSCs","bone marrow","patients with GC-ONFH (n = 13)","glucocorticoid treatment (steroid-induced osteonecrosis of femoral head model)","miR-30a",0.6,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]
["MiR-708 promotes steroid- induced osteonecrosis of femoral head , suppresses osteogenic differentiation by targeting SMAD3","hMSCs","bone marrow","patients with GC-ONFH (n = 13)","dexamethazone 10-8 M + glucocorticoid treatment (steroid-induced osteonecrosis of femoral head model)","miR-30a",2,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]
["MiR-708 promotes steroid- induced osteonecrosis of femoral head , suppresses osteogenic differentiation by targeting SMAD3","hMSCs","bone marrow","patients with GC-ONFH (n = 13)","dexamethazone 10-7 M + glucocorticoid treatment (steroid-induced osteonecrosis of femoral head model)","miR-30a",2.5,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]
["MiR-708 promotes steroid- induced osteonecrosis of femoral head , suppresses osteogenic differentiation by targeting SMAD3","hMSCs","bone marrow","patients with GC-ONFH (n = 13)","dexamethazone 10-6 M + glucocorticoid treatment (steroid-induced osteonecrosis of femoral head model)","miR-30a",1.1,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]
["miR-214 targets ATF4 to inhibit bone formation",null,"bone sample",null,"osteoporotic female (70-79 y.o.)","miR-30a",13,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]
["miR-214 targets ATF4 to inhibit bone formation",null,"bone sample",null,"osteoporotic female (80-89 y.o.)","miR-30a",9.5,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]
["miR-214 targets ATF4 to inhibit bone formation",null,"bone sample",null,"osteoporotic male (70-79 y.o.)","miR-30a",8.6,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]
["miR-214 targets ATF4 to inhibit bone formation",null,"bone sample",null,"osteoporotic male (80-89 y.o.)","miR-30a",9.7,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]

{"sheet":"mir-30b","index":50,"n_rows":3,"n_cols":19,"rows_kept":3,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["MicroRNAs miR-26a, miR-26b, and miR-29b accelerate osteogenic differentiation of unrestricted somatic stem cells from human cord blood","SA5/73","USSC, human cord blood",null,"7 day after osteogenic stimuli","miR-30b",5,{"$nulls":4},"microarrays"]
["MicroRNAs miR-26a, miR-26b, and miR-29b accelerate osteogenic differentiation of unrestricted somatic stem cells from human cord blood","SA8/25","USSC, human cord blood",null,"7 day after osteogenic stimuli","miR-30b",10,{"$nulls":4},"microarrays"]

{"sheet":"mir-30c","index":51,"n_rows":7,"n_cols":19,"rows_kept":7,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["MicroRNAs miR-26a, miR-26b, and miR-29b accelerate osteogenic differentiation of unrestricted somatic stem cells from human cord blood","SA5/73","USSC, human cord blood",null,"7 day after osteogenic stimuli","miR-30c",3,{"$nulls":4},"microarrays"]
["MicroRNAs miR-26a, miR-26b, and miR-29b accelerate osteogenic differentiation of unrestricted somatic stem cells from human cord blood","SA8/25","USSC, human cord blood",null,"7 day after osteogenic stimuli","miR-30c",6,{"$nulls":4},"microarrays"]
["MicroRNA-138 regulates osteogenic differentiation of human stromal (mesenchymal) stem cells in vivo","hMSCs","telomerase immortalized bone marrow",null,"osteogenic differentiation 10 day","miR-30c",1.6701758388567387,0.74,{"$nulls":3},"RT-qPCR",null,"mean ± SD"]
["MiR-590-3p regulates osteogenic differentiation of human mesenchymal stem cells by regulating APC gene","HMSCs",null,null,"osteogenic differentiation 25 day","miR-30c",1.5,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]
["MicroRNA-138 regulates osteogenic differentiation of human stromal (mesenchymal) stem cells in vivo","hMSCs","telomerase immortalized bone marrow",null,"osteogenic differentiation 10 day","miR-30c ",1.1647335864684558,0.22,{"$nulls":3},"microarrays",null,"mean ± SD"]
["Adipogenic RNAs are transferred in osteoblasts via bone marrow adipocytes-derived extracellular vesicles ( EVs )","hMSC-Ost","purified",null,"14 days-differentiated osteoblasts incubated with conditioned medium from 14 days-differentiated adipocytes","miR-30c",0.5,{"$nulls":4},"RT-qPCR",null,"median of experimental data"]

{"sheet":"mir-30e","index":52,"n_rows":2,"n_cols":19,"rows_kept":2,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["MiR-27a is Essential for the Shift from Osteogenic Differentiation to Adipogenic Differentiation of Mesenchymal Stem Cells in Postmenopausal Osteoporosis",null,"serum",null,"osteoporosis","miR-30e",52.0858,{"$nulls":4},"microarrays"]

{"sheet":"mir-31","index":53,"n_rows":33,"n_cols":19,"rows_kept":33,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["The Effects of BMP-2, miR-31, miR-106a, and miR-148a on Osteogenic Differentiation of MSCs Derived from Amnion in Comparison with MSCs Derived from the Bone Marrow","AM-MSCs","amniotic tissues","4 donors","osteogenic differentiation 3 day","miR-31",0.89,{"$nulls":4},"RT-qPCR",null,"mean±SEM, unpaired t test"]
["The Effects of BMP-2, miR-31, miR-106a, and miR-148a on Osteogenic Differentiation of MSCs Derived from Amnion in Comparison with MSCs Derived from the Bone Marrow","AM-MSCs","amniotic tissues","4 donors","osteogenic differentiation 7 day","miR-31",0.82,{"$nulls":4},"RT-qPCR",null,"mean±SEM, unpaired t test"]
["The Effects of BMP-2, miR-31, miR-106a, and miR-148a on Osteogenic Differentiation of MSCs Derived from Amnion in Comparison with MSCs Derived from the Bone Marrow","AM-MSCs","amniotic tissues","4 donors","osteogenic differentiation 14 day","miR-31",0.62,{"$nulls":4},"RT-qPCR",null,"mean±SEM, unpaired t test"]
["The Effects of BMP-2, miR-31, miR-106a, and miR-148a on Osteogenic Differentiation of MSCs Derived from Amnion in Comparison with MSCs Derived from the Bone Marrow","AM-MSCs","amniotic tissues","4 donors","osteogenic differentiation 21 day","miR-31",0.43,{"$nulls":4},"RT-qPCR",null,"mean±SEM, unpaired t test"]
["The Effects of BMP-2, miR-31, miR-106a, and miR-148a on Osteogenic Differentiation of MSCs Derived from Amnion in Comparison with MSCs Derived from the Bone Marrow","AM-MSCs","amniotic tissues","4 donors","osteogenic differentiation 28 day","miR-31",0.4,{"$nulls":4},"RT-qPCR",null,"mean±SEM, unpaired t test"]
["The Effects of BMP-2, miR-31, miR-106a, and miR-148a on Osteogenic Differentiation of MSCs Derived from Amnion in Comparison with MSCs Derived from the Bone Marrow","AM-MSCs","amniotic tissues","4 donors","BMP-2 induced osteogenic differentiation 3 day","miR-31",0.85,{"$nulls":4},"RT-qPCR",null,"mean±SEM, unpaired t test"]
["The Effects of BMP-2, miR-31, miR-106a, and miR-148a on Osteogenic Differentiation of MSCs Derived from Amnion in Comparison with MSCs Derived from the Bone Marrow","AM-MSCs","amniotic tissues","4 donors","BMP-2 induced osteogenic differentiation 7 day","miR-31",0.8,{"$nulls":4},"RT-qPCR",null,"mean±SEM, unpaired t test"]
["The Effects of BMP-2, miR-31, miR-106a, and miR-148a on Osteogenic Differentiation of MSCs Derived from Amnion in Comparison with MSCs Derived from the Bone Marrow","AM-MSCs","amniotic tissues","4 donors","BMP-2 induced osteogenic differentiation 14 day","miR-31",0.54,{"$nulls":4},"RT-qPCR",null,"mean±SEM, unpaired t test"]
["The Effects of BMP-2, miR-31, miR-106a, and miR-148a on Osteogenic Differentiation of MSCs Derived from Amnion in Comparison with MSCs Derived from the Bone Marrow","AM-MSCs","amniotic tissues","4 donors","BMP-2 induced osteogenic differentiation 21 day","miR-31",0.35,{"$nulls":4},"RT-qPCR",null,"mean±SEM, unpaired t test"]
["The Effects of BMP-2, miR-31, miR-106a, and miR-148a on Osteogenic Differentiation of MSCs Derived from Amnion in Comparison with MSCs Derived from the Bone Marrow","AM-MSCs","amniotic tissues","4 donors","BMP-2 induced osteogenic differentiation 28 day","miR-31",0.3,{"$nulls":4},"RT-qPCR",null,"mean±SEM, unpaired t test"]
["The Effects of BMP-2, miR-31, miR-106a, and miR-148a on Osteogenic Differentiation of MSCs Derived from Amnion in Comparison with MSCs Derived from the Bone Marrow","BMMSCs","bone marrow","healthy donors (n =4) were <60 years","osteogenic differentiation 3 day","miR-31",0.78,{"$nulls":4},"RT-qPCR",null,"mean±SEM, unpaired t test"]
["The Effects of BMP-2, miR-31, miR-106a, and miR-148a on Osteogenic Differentiation of MSCs Derived from Amnion in Comparison with MSCs Derived from the Bone Marrow","BMMSCs","bone marrow","healthy donors (n =4) were <60 years","osteogenic differentiation 7 day","miR-31",0.58,{"$nulls":4},"RT-qPCR",null,"mean±SEM, unpaired t test"]
["The Effects of BMP-2, miR-31, miR-106a, and miR-148a on Osteogenic Differentiation of MSCs Derived from Amnion in Comparison with MSCs Derived from the Bone Marrow","BMMSCs","bone marrow","healthy donors (n =4) were <60 years","osteogenic differentiation 14 day","miR-31",0.3,{"$nulls":4},"RT-qPCR",null,"mean±SEM, unpaired t test"]
["The Effects of BMP-2, miR-31, miR-106a, and miR-148a on Osteogenic Differentiation of MSCs Derived from Amnion in Comparison with MSCs Derived from the Bone Marrow","BMMSCs","bone marrow","healthy donors (n =4) were <60 years","osteogenic differentiation 21 day","miR-31",0.2,{"$nulls":4},"RT-qPCR",null,"mean±SEM, unpaired t test"]
["The Effects of BMP-2, miR-31, miR-106a, and miR-148a on Osteogenic Differentiation of MSCs Derived from Amnion in Comparison with MSCs Derived from the Bone Marrow","BMMSCs","bone marrow","healthy donors (n =4) were <60 years","osteogenic differentiation 28 day","miR-31",0.18,{"$nulls":4},"RT-qPCR",null,"mean±SEM, unpaired t test"]
["The Effects of BMP-2, miR-31, miR-106a, and miR-148a on Osteogenic Differentiation of MSCs Derived from Amnion in Comparison with MSCs Derived from the Bone Marrow","BMMSCs","bone marrow","healthy donors (n =4) were <60 years","BMP-2 induced osteogenic differentiation 3 day","miR-31",0.65,{"$nulls":4},"RT-qPCR",null,"mean±SEM, unpaired t test"]
["The Effects of BMP-2, miR-31, miR-106a, and miR-148a on Osteogenic Differentiation of MSCs Derived from Amnion in Comparison with MSCs Derived from the Bone Marrow","BMMSCs","bone marrow","healthy donors (n =4) were <60 years","BMP-2 induced osteogenic differentiation 7 day","miR-31",0.4,{"$nulls":4},"RT-qPCR",null,"mean±SEM, unpaired t test"]
["The Effects of BMP-2, miR-31, miR-106a, and miR-148a on Osteogenic Differentiation of MSCs Derived from Amnion in Comparison with MSCs Derived from the Bone Marrow","BMMSCs","bone marrow","healthy donors (n =4) were <60 years","BMP-2 induced osteogenic differentiation 14 day","miR-31",0.25,{"$nulls":4},"RT-qPCR",null,"mean±SEM, unpaired t test"]
["The Effects of BMP-2, miR-31, miR-106a, and miR-148a on Osteogenic Differentiation of MSCs Derived from Amnion in Comparison with MSCs Derived from the Bone Marrow","BMMSCs","bone marrow","healthy donors (n =4) were <60 years","BMP-2 induced osteogenic differentiation 21 day","miR-31",0.15,{"$nulls":4},"RT-qPCR",null,"mean±SEM, unpaired t test"]
["The Effects of BMP-2, miR-31, miR-106a, and miR-148a on Osteogenic Differentiation of MSCs Derived from Amnion in Comparison with MSCs Derived from the Bone Marrow","BMMSCs","bone marrow","healthy donors (n =4) were <60 years","BMP-2 induced osteogenic differentiation 28 day","miR-31",0.15,{"$nulls":4},"RT-qPCR",null,"mean±SEM, unpaired t test"]
["Adipogenic RNAs are transferred in osteoblasts via bone marrow adipocytes-derived extracellular vesicles ( EVs )","hMSC-Ost","purified",null,"14 days-differentiated osteoblasts incubated with conditioned medium from 14 days-differentiated adipocytes","miR-31",0.45,{"$nulls":4},"RT-qPCR",null,"median of experimental data"]
["MicroRNA-138 regulates osteogenic differentiation of human stromal (mesenchymal) stem cells in vivo","hMSCs","telomerase immortalized bone marrow",null,"osteogenic differentiation 10 day","miR-31 ",0.6877709090698718,-0.54,{"$nulls":3},"microarrays",null,"mean ± SD"]
["Effects of miR-31 on the osteogenesis of human mesenchymal stem cells","hMSCs",{"$nulls":3},"miR-31",{"$nulls":8},"SATB2 decrease","down"]
["MicroRNA expression pro fi ling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-149",{"$nulls":4},"miR-31",{"$nulls":8},"Osterix decrease"]
["The Effects of BMP-2, miR-31, miR-106a, and miR-148a on Osteogenic Differentiation of MSCs Derived from Amnion in Comparison with MSCs Derived from the Bone Marrow",{"$nulls":4},"miR-31",{"$nulls":11},"up"]
["Secreted microvesicular miR-31 inhibits osteogenic differentiation of mesenchymal stem cells",{"$nulls":4},"miR-31",{"$nulls":9},"down",null,"up"]
["Global miRNA expression and correlation with mRNA levels in primary human bone cells","HOBs (primary human osteoblasts)","trabecular bone",null,"male","miR-31",1.2,{"$nulls":4},"RT-qPCR",null,"Student’s t-test"]
["Global miRNA expression and correlation with mRNA levels in primary human bone cells","HOBs (primary human osteoblasts)","trabecular bone",null,"female","miR-31",2,{"$nulls":4},"RT-qPCR",null,"Student’s t-test"]
["Altered function in cartilage derived mesenchymal stem cell leads to OA-related cartilage erosion","CMSC","medial and lateral condyles","12 patients (4 males, 8 females, median age 67.8 years, range 47-79 years)","osteoarthritis","miR-31",null,"-2.851141",{"$nulls":3},"microarrays"]
["MicroRNA expression pro fi ling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-70","MSCs","bone marrow","3 donors","full confluence of the culture after the addition of the differentiating medium vs control","miR-31",null,"1.12349  ",{"$nulls":3},"microarrays"]
["MicroRNA expression pro fi ling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-71","MSCs","bone marrow","3 donors","full confluence of the culture after the addition of the differentiating medium vs control","miR-31",null,"0.765812",{"$nulls":3},"microarrays"]
["MicroRNA expression pro fi ling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-72","MSCs","bone marrow","3 donors","full confluence of the culture after the addition of the differentiating medium vs control","miR-31",null,"1.13945",{"$nulls":3},"microarrays"]

{"sheet":"mir-31-5p","index":54,"n_rows":6,"n_cols":19,"rows_kept":6,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["Altered function in cartilage derived mesenchymal stem cell leads to OA-related cartilage erosion","CMSC","medial and lateral condyles","12 patients (4 males, 8 females, median age 67.8 years, range 47-79 years)","osteoarthritis","miR-31-5p",1,{"$nulls":4},"RT-qPCR",null,"mean+SEM"]
["Altered function in cartilage derived mesenchymal stem cell leads to OA-related cartilage erosion","CMSC","medial and lateral condyles","12 patients (4 males, 8 females, median age 67.8 years, range 47-79 years)","osteoarthritis","miR-31-5p",0.75,{"$nulls":4},"RT-qPCR",null,"mean+SEM"]
["Differentially Expressed MicroRNAs in Conservatively Treated Nontraumatic Osteonecrosis Compared with Healthy Controls",null,null,"43 patients with ONFH-N and 43 par- ticipants without ONFH-N","Osteonecrosis of the femoral head (ONFH)","miR-31-5p",0.7,{"$nulls":4},"RT-qPCR","ns","mean ± SD, Student t test"]
["Nanoparticle-AntagoMIR based targeting of MIR-31 to induce osterix and osteocalcin expression in mesenchymal stem cells","hMSCs","bone marrow",null,"gold nanoparticles with antagomir-31 + osteogenesis","miR-31-5p",{"$nulls":11},"up","more efficient"]
["Mesenchymal stem cell-derived exosomes have altered microRNA profiles and induce osteogenic differentiation depending on the stage of differentiation","hMSCs",null,null,"exosomes from hMSC under osteogenesis 21 days","miR-31-5p",-4.1,{"$nulls":4},"microarrays",null,"mean ± SEM, pairwise t test"]

{"sheet":"mir-335","index":55,"n_rows":9,"n_cols":19,"rows_kept":9,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["Signature of microRNA expression during osteogenic differentiation of bone marrow MSCs reveals a putative role of miR-335-5p in osteoarthritis","BM-MSCs","bone marrow from hip, patients with osteoarthrosis",null,"osteoarthrosis, osteogenic differentiation 0 day","miR-335",{"$nulls":3},19.5,null,"microarrays","ns control to osteoarthrosis"]
["Signature of microRNA expression during osteogenic differentiation of bone marrow MSCs reveals a putative role of miR-335-5p in osteoarthritis","BM-MSCs","bone marrow from hip, patients with osteoarthrosis",null,"osteoarthrosis, osteogenic differentiation 10 day","miR-335",{"$nulls":3},20.5,null,"microarrays","ns control to osteoarthrosis"]
["Signature of microRNA expression during osteogenic differentiation of bone marrow MSCs reveals a putative role of miR-335-5p in osteoarthritis","BM-MSCs","bone marrow from hip, patients with osteoarthrosis",null,"osteoarthrosis, osteogenic differentiation 21 day","miR-335",{"$nulls":3},24,null,"microarrays","ns control to osteoarthrosis"]
["miR-335 orchestrates cell proliferation , migration and differentiation in human mesenchymal stem cells","hMSCs","bone marrow",null,"osteogenic differentiation 9 days","miR-335",0.25,{"$nulls":4},"RT-qPCR",null,"mean+SEM","RUNX2 decrease"]
["miR-335 orchestrates cell proliferation , migration and differentiation in human mesenchymal stem cells","hMSCs","bone marrow",null,"osteogenic differentiation 9 days","miR-335",0.2,{"$nulls":4},"microarrays",null,"mean+SEM","RUNX2 decrease"]
["Global miRNA expression and correlation with mRNA levels in primary human bone cells","HOBs (primary human osteoblasts)","trabecular bone",null,"male","miR-335",1.4,{"$nulls":4},"RT-qPCR",null,"Student’s t-test"]
["Global miRNA expression and correlation with mRNA levels in primary human bone cells","HOBs (primary human osteoblasts)","trabecular bone",null,"female","miR-335",1.9,{"$nulls":4},"RT-qPCR",null,"Student’s t-test"]
["Mir-335 Correlates with Senescence/Aging in Human Mesenchymal Stem Cells and Inhibits their Therapeutic Actions through Inhibition of AP-1 Activity","hMSCs",null,null,"miR-335-hMCSs diffusion chambers in a rat model of osteogenesis","miR-335",{"$nulls":9},"down"]

{"sheet":"mir-335-5p","index":56,"n_rows":11,"n_cols":19,"rows_kept":11,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["Signature of microRNA expression during osteogenic differentiation of bone marrow MSCs reveals a putative role of miR-335-5p in osteoarthritis","BM-MSCs","bone marrow from hip, patients with osteoarthrosis",10,"control","miR-335-5p",13,{"$nulls":4},"RT-qPCR"]
["Signature of microRNA expression during osteogenic differentiation of bone marrow MSCs reveals a putative role of miR-335-5p in osteoarthritis","BM-MSCs","bone marrow from femoral neck fracture",10,"osteoarthrosis","miR-335-5p",4,{"$nulls":4},"RT-qPCR"]
["MiRNA expression in the cartilage of patients with osteoarthritis",null,"femoral heads","29 OA patients","osteoarthritis","miR-335-5p",6.5,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]
["Differentially Expressed MicroRNAs in Conservatively Treated Nontraumatic Osteonecrosis Compared with Healthy Controls",null,null,"43 patients with ONFH-N and 43 par- ticipants without ONFH-N","Osteonecrosis of the femoral head (ONFH)","miR-335-5p",0.3,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]
["Differentially Expressed MicroRNAs in Conservatively Treated Nontraumatic Osteonecrosis Compared with Healthy Controls",null,null,"80 samples (n=40/group)","Osteonecrosis of the femoral head (ONFH)","miR-335-5p",1.3,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]
["Signature of microRNA expression during osteogenic differentiation of bone marrow MSCs reveals a putative role of miR-335-5p in osteoarthritis","BM-MSCs","bone marrow from femoral neck fracture","(?) 10","control, osteogenic differentiation 21 day","miR-335-5p",12.5,{"$nulls":4},"RT-qPCR","fold downregularion","Parametric test (Limma)"]
["Differentially Expressed MicroRNAs in Conservatively Treated Nontraumatic Osteonecrosis Compared with Healthy Controls",null,null,"80 samples (n=40/group)","normal","miR-335-5p",2,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]
["Signature of microRNA expression during osteogenic differentiation of bone marrow MSCs reveals a putative role of miR-335-5p in osteoarthritis","BM-MSCs","bone marrow from femoral neck fracture",10,"control, osteogenic differentiation 10 day","miR-335-5p",2.5,{"$nulls":4},"RT-qPCR","fold downregularion","Parametric test (Limma)"]
["Signature of microRNA expression during osteogenic differentiation of bone marrow MSCs reveals a putative role of miR-335-5p in osteoarthritis","BM-MSCs","bone marrow from hip, patients with osteoarthrosis",10,"osteoarthrosis, osteogenic differentiation 10 day","miR-335-5p",2,{"$nulls":4},"RT-qPCR","fold downregularion","Parametric test (Limma)"]
["Signature of microRNA expression during osteogenic differentiation of bone marrow MSCs reveals a putative role of miR-335-5p in osteoarthritis","BM-MSCs","bone marrow from hip, patients with osteoarthrosis",10,"osteoarthrosis, osteogenic differentiation 21 day","miR-335-5p",12.5,{"$nulls":4},"RT-qPCR","fold downregularion","Parametric test (Limma)"]

{"sheet":"mir-34a","index":57,"n_rows":16,"n_cols":19,"rows_kept":16,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["Osteogenic Differentiation of Human Amniotic Fluid Mesenchymal Stem Cells Is Determined by Epigenetic Changes","AF-MSCs","amniotic fluid","second trimester, healthy women","osteogenic differentiation 5 day","miR-34a",0.5,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]
["Osteogenic Differentiation of Human Amniotic Fluid Mesenchymal Stem Cells Is Determined by Epigenetic Changes","AF-MSCs","amniotic fluid","second trimester, healthy women","osteogenic differentiation 9 day","miR-34a",0.35,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]
["Osteogenic Differentiation of Human Amniotic Fluid Mesenchymal Stem Cells Is Determined by Epigenetic Changes","AF-MSCs","amniotic fluid","second trimester, healthy women","osteogenic differentiation 15 day","miR-34a",0.5,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]
["MiR-34a Promotes Osteogenic Differentiation of Human Adipose-Derived Stem Cells via the RBP2/NOTCH1/CYCLIN D1 Coregulatory Network","hASCs","adipose tissue","three donors, third passage","odontoblast differentiation 6 hours","miR-34a",1.1,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]
["MiR-34a Promotes Osteogenic Differentiation of Human Adipose-Derived Stem Cells via the RBP2/NOTCH1/CYCLIN D1 Coregulatory Network","hASCs","adipose tissue","three donors, third passage","odontoblast differentiation 12 hours","miR-34a",1.4,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]
["MiR-34a Promotes Osteogenic Differentiation of Human Adipose-Derived Stem Cells via the RBP2/NOTCH1/CYCLIN D1 Coregulatory Network","hASCs","adipose tissue","three donors, third passage","odontoblast differentiation 1 day","miR-34a",2,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]
["MiR-34a Promotes Osteogenic Differentiation of Human Adipose-Derived Stem Cells via the RBP2/NOTCH1/CYCLIN D1 Coregulatory Network","hASCs","adipose tissue","three donors, third passage","odontoblast differentiation 3 day","miR-34a",2.8,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]
["MiR-34a Promotes Osteogenic Differentiation of Human Adipose-Derived Stem Cells via the RBP2/NOTCH1/CYCLIN D1 Coregulatory Network","hASCs","adipose tissue","three donors, third passage","odontoblast differentiation 5 day","miR-34a",3,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]
["MiR-34a Promotes Osteogenic Differentiation of Human Adipose-Derived Stem Cells via the RBP2/NOTCH1/CYCLIN D1 Coregulatory Network","hASCs","adipose tissue","three donors, third passage","odontoblast differentiation 7 day","miR-34a",3.2,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]
["MiR-34a Promotes Osteogenic Differentiation of Human Adipose-Derived Stem Cells via the RBP2/NOTCH1/CYCLIN D1 Coregulatory Network","hASCs","adipose tissue","three donors, third passage","odontoblast differentiation 14 day","miR-34a",3.25,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Student t test"]
["MiR-34a Promotes Osteogenic Differentiation of Human Adipose-Derived Stem Cells via the RBP2/NOTCH1/CYCLIN D1 Coregulatory Network","hASCs","adipose tissue","three donors, third passage",null,"miR-34a",{"$nulls":8},"RBP2 decrease","up"]
["MiR-34a Promotes Osteogenic Differentiation of Human Adipose-Derived Stem Cells via the RBP2/NOTCH1/CYCLIN D1 Coregulatory Network","hASCs","adipose tissue","three donors, third passage",null,"miR-34a",{"$nulls":8},"NOTCH1 decrease","up"]
["MiR-34a Promotes Osteogenic Differentiation of Human Adipose-Derived Stem Cells via the RBP2/NOTCH1/CYCLIN D1 Coregulatory Network","hASCs","adipose tissue","three donors, third passage",null,"miR-34a",{"$nulls":8},"CYCLIN D1 decrease","up"]
["MiR-34a Promotes Osteogenic Differentiation of Human Adipose-Derived Stem Cells via the RBP2/NOTCH1/CYCLIN D1 Coregulatory Network","hASCs","adipose tissue","three donors, third passage",null,"miR-34a",{"$nulls":8},"RUNX2 upregulation","up"]
["MicroRNA-146a regulates human foetal femur derived skeletal stem cell differentiation by down-regulating SMAD2 and SMAD8","SSCs (skeletal stem cells)","foetal femur","7–9 weeks fetuses","osteogenic diaphyseal cells","miR-34a",{"$nulls":3},9.09,null,"microarrays",null,"t-test"]

{"sheet":"mir-34c","index":58,"n_rows":8,"n_cols":19,"rows_kept":8,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["miR-216a rescues dexamethasone suppression of osteogenesis , promotes osteoblast differentiation and enhances bone formation , by regulating c-Cbl-mediated PI3K / AKT pathway","hAMSCs","adipose tissue","healthy donors","osteogenic differentiation 4 day 1 sample","miR-34c",76.72857200239865,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]
["miR-216a rescues dexamethasone suppression of osteogenesis , promotes osteoblast differentiation and enhances bone formation , by regulating c-Cbl-mediated PI3K / AKT pathway","hAMSCs","adipose tissue","healthy donors","osteogenic differentiation 4 day 2 sample","miR-34c",33.537052640133965,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]
["miR-216a rescues dexamethasone suppression of osteogenesis , promotes osteoblast differentiation and enhances bone formation , by regulating c-Cbl-mediated PI3K / AKT pathway","hAMSCs","adipose tissue","healthy donors","osteogenic differentiation 4 day 3 sample","miR-34c",16.29654241677579,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]
["MicroRNA expression pro fi ling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-115","MSCs","bone marrow","3 donors","full confluence of the culture after the addition of the differentiating medium vs control","miR-34c",null,"−0.314645 ",{"$nulls":3},"microarrays"]
["MicroRNA expression pro fi ling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-116","MSCs","bone marrow","3 donors","full confluence of the culture after the addition of the differentiating medium vs control","miR-34c",null,"−0.651469",{"$nulls":3},"microarrays"]
["MicroRNA expression pro fi ling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-117","MSCs","bone marrow","3 donors","full confluence of the culture after the addition of the differentiating medium vs control","miR-34c",null," −0.84806",{"$nulls":3},"microarrays"]
["miRNA-34c regulates Notch signaling during bone development","BMSCs","bone marrow","8-12 week-old mice","control","miR-34c",1.4,{"$nulls":4},"RT-qPCR",null,"Student’s t-test","Notch1 decrease","down"]

{"sheet":"mir-483","index":59,"n_rows":6,"n_cols":19,"rows_kept":6,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["Identification and differential expression of microRNAs differentiation of human adipose-derived mesenchymal stem cells","hAMSCs","adipose tissue","healthy patients (average age 38 years)","1, 25-dihydroxyvitamin D3-induced (VD3-induced) osteogenic differentiation","miR-483",6.3,{"$nulls":4},"RT-qPCR",null,"mean±SEM, Student t test"]
["MicroRNAs miR-26a, miR-26b, and miR-29b accelerate osteogenic differentiation of unrestricted somatic stem cells from human cord blood","SA5/73","USSC, human cord blood",null,"7 day after osteogenic stimuli","miR-483",225,{"$nulls":4},"microarrays"]
["MicroRNAs miR-26a, miR-26b, and miR-29b accelerate osteogenic differentiation of unrestricted somatic stem cells from human cord blood","SA8/25","USSC, human cord blood",null,"7 day after osteogenic stimuli","miR-483",749,{"$nulls":4},"microarrays"]
["MicroRNA-138 regulates osteogenic differentiation of human stromal (mesenchymal) stem cells in vivo","hMSCs","telomerase immortalized bone marrow",null,"osteogenic differentiation 10 day","miR-483 ",1.4539725173203106,0.54,{"$nulls":3},"microarrays",null,"mean ± SD"]
["MiR-590-3p regulates osteogenic differentiation of human mesenchymal stem cells by regulating APC gene","HMSCs",null,null,"osteogenic differentiation 25 day","miR-483 ",1.3,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]

{"sheet":"mir-503","index":60,"n_rows":4,"n_cols":19,"rows_kept":4,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["miR-146a-5p circuitry uncouples cell proliferation and migration, but not differentiation, in human mesenchymal stem cells Jui-Yu","BMSCs","bone marrow",null,"differentiated to osteocytes","miR-503",0.5,{"$nulls":4},"RT-qPCR",null,"mean ± SD"]
["Global miRNA expression and correlation with mRNA levels in primary human bone cells","HOBs (primary human osteoblasts)","trabecular bone",null,"male","miR-503",1.2,{"$nulls":4},"RT-qPCR",null,"Student’s t-test"]
["Global miRNA expression and correlation with mRNA levels in primary human bone cells","HOBs (primary human osteoblasts)","trabecular bone",null,"female","miR-503",1.2,{"$nulls":4},"RT-qPCR",null,"Student’s t-test"]

{"sheet":"mir-96","index":61,"n_rows":6,"n_cols":19,"rows_kept":6,"flags":["formulas_cached_only"]}
["Title","Cell culture","Source of cells","Donors/animal model/quantity of samples","Process","miR","fc","log fc","%","mean dct","fragments per kilobase of transcript per million (FPKM)","method","up/down","test","prots interactions by overexpressiom","osteogenesis (overexpression)","osteoclastogenesis","osteogenesis (anti-miR)","notes"]
["MiR-96 regulates bone metabolism by targeting osterix","BMSCs","bone marrow",null,"female aging","miR-96",5.6,{"$nulls":4},"RT-qPCR",null,"mean ± SD","osterix decrease"]
["MiR-96 regulates bone metabolism by targeting osterix","BMSCs","bone marrow",null,"male aging","miR-96",3.6,{"$nulls":4},"RT-qPCR",null,"mean ± SD","osterix decrease"]
["MicroRNAs miR-96, miR-124, and miR-199a Regulate Gene Expression in Human Bone Marrow-Derived Mesenchymal Stem Cells","hMSCs","iliac bone","4 adult females (age 19–38 years)","control","miR-96",6,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Friedman test followed by the Wilcoxon test for paired comparisons"]
["MicroRNAs miR-96, miR-124, and miR-199a Regulate Gene Expression in Human Bone Marrow-Derived Mesenchymal Stem Cells","hMSCs","iliac bone","5 adult females (age 19–38 years)","osteogenic differentiation","miR-96",19,{"$nulls":4},"RT-qPCR",null,"mean ± SD, Friedman test followed by the Wilcoxon test for paired comparisons"]
["Decoding the regulatory landscape of ageing in musculoskeletal engineered tissues using genome-wide DNA methylation and RNASeq","MSCs",null,"old n = 4 (65.5years±8.3SD) donors, 4 passage","age related changes in osteogenic tissue","miR-96",369.6458740537589,8.53,{"$nulls":3},"RT-qPCR",null,"mean±SEM"]