\begin{tabular}{llllll}
\toprule
Preferred term & Primary SOC & Domain & Durvalumab reports, n (\%) & ROR (95\% CI) & IC025 \\
\midrule
Myocarditis & Cardiac disorders & Cardiac & 82 (0.9) & 62.79 (48.80, 80.78) & 3.39 \\
Immune-mediated myocarditis & Cardiac disorders & Cardiac & 57 (0.6) & 451.03 (276.91, 734.61) & 2.77 \\
Cardiac failure & Cardiac disorders & Cardiac & 51 (0.5) & 42.94 (31.65, 58.27) & 2.76 \\
Pericardial effusion & Cardiac disorders & Cardiac & 29 (0.3) & 51.14 (33.92, 77.09) & 1.99 \\
Pericarditis & Cardiac disorders & Cardiac & 17 (0.2) & 62.13 (36.01, 107.19) & 0.89 \\
Rash & Skin and subcutaneous tissue disorders & Dermatologic & 214 (2.3) & 73.82 (62.88, 86.65) & 4.29 \\
Pruritus & Skin and subcutaneous tissue disorders & Dermatologic & 93 (1.0) & 68.02 (53.54, 86.42) & 3.55 \\
Dermatitis & Skin and subcutaneous tissue disorders & Dermatologic & 19 (0.2) & 41.05 (25.06, 67.23) & 1.31 \\
Psoriasis & Skin and subcutaneous tissue disorders & Dermatologic & 18 (0.2) & 54.64 (32.42, 92.11) & 1.08 \\
Stevens-Johnson syndrome & Skin and subcutaneous tissue disorders & Dermatologic & 16 (0.2) & 46.39 (26.95, 79.83) & 0.92 \\
Pemphigoid & Skin and subcutaneous tissue disorders & Dermatologic & 15 (0.2) & 64.08 (35.81, 114.66) & 0.58 \\
Hypothyroidism & Endocrine disorders & Endocrine & 154 (1.6) & 58.67 (48.86, 70.45) & 3.93 \\
Adrenal insufficiency & Endocrine disorders & Endocrine & 91 (1.0) & 44.58 (35.41, 56.12) & 3.36 \\
Hyperthyroidism & Endocrine disorders & Endocrine & 68 (0.7) & 60.36 (45.85, 79.47) & 3.17 \\
Diabetic ketoacidosis & Metabolism and nutrition disorders & Endocrine & 38 (0.4) & 91.02 (61.65, 134.37) & 2.35 \\
Type 1 diabetes mellitus & Metabolism and nutrition disorders & Endocrine & 35 (0.4) & 52.74 (36.23, 76.79) & 2.28 \\
Thyroiditis & Endocrine disorders & Endocrine & 30 (0.3) & 69.25 (45.53, 105.34) & 1.99 \\
Hypopituitarism & Endocrine disorders & Endocrine & 26 (0.3) & 72.27 (45.96, 113.65) & 1.71 \\
Hypophysitis & Endocrine disorders & Endocrine & 22 (0.2) & 46.82 (29.39, 74.56) & 1.53 \\
Colitis & Gastrointestinal disorders & Gastrointestinal & 123 (1.3) & 49.15 (40.23, 60.05) & 3.66 \\
\bottomrule
\end{tabular}
