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["Table 3  Candidate drugs targeting hub genes"]
["Number","Gene","Drug","Interaction types","Scorea","PubMed ID"]
[1,"AURKA","PACLITAXEL","-",2,12559175]
[2,"AURKA","TAMOXIFEN","-",2,24166501]
[3,"AURKA","FLUOROURACIL","-",2,25924824]
[4,"CCNA2","ETHINYL ESTRADIOL","-",2,9806355]
[5,"MKI67","SUNITINIB","-",1,"-"]
[6,"EZH2","DOXORUBICIN","-",2,25605023]
[7,"EZH2","VORINOSTAT","-",2,25605023]
[8,"EZH2","DABRAFENIB","-",2,27135738]
[9,"EZH2","SULFINPYRAZONE","-",2,28135237]
[10,"CDK1","ELTROMBOPAG","agonist",1,"-"]
[11,"CDK1","ROMIPLOSTIM","agonist",1,"-"]
[12,"TOP2A","DOXORUBICIN HYDROCHLORIDE","inhibitor",1,"-"]
[13,"TOP2A","TENIPOSIDE","inhibitor",12,"8702194;16271071;17361331; 17514873;11752352;16480143; 9426516"]
[14,"TOP2A","ETOPOSIDE","inhibitor",12,"8823806;9485461;8870683; 9494516;9426516"]
[15,"TOP2A","VINCRISTINE","-",10,9494516]
[16,"TOP2A","DOXORUBICIN","inhibitor",4,"-"]
[17,"TOP2A","NORFLOXACIN","inhibitor",2,11752352]
[18,"TOP2A","VALRUBICIN","inhibitor",6,"11752352;16019763"]
[19,"TOP2A","LEVOFLOXACIN","inhibitor",2,11752352]
[20,"TOP2A","ENOXACIN","inhibitor",4,"18471102;11752352;10089819"]
[21,"TOP2A","ETOPOSIDE PHOSPHATE","inhibitor",1,"-"]
[22,"TOP2A","PACLITAXEL","-",1,"-"]
[23,"TOP2A","DAUNORUBICIN","-",3,9494516]
[24,"TOP2A","OFLOXACIN","inhibitor",2,2847647]
[25,"TOP2A","IDARUBICIN HYDROCHLORIDE","inhibitor",1,"-"]
[26,"TOP2A","PEFLOXACIN","inhibitor",2,11752352]
[27,"TOP2A","DAUNORUBICIN HYDROCHLORIDE","inhibitor",1,"-"]
[28,"TOP2A","MITOXANTRONE DIHYDROCHLORIDE","inhibitor",1,"-"]
[29,"TOP2A","AMSACRINE","inhibitor",12,"1322791;8823806;10691026;   8519659;8632768;11006484;  11716434;11752352; 11473732;1311390"]
[30,"TOP2A","PODOFILOX","inhibitor",9,"16061385;1334447;10783066; 11752352;1845848;1331331"]
[31,"TOP2A","DEXRAZOXANE","-",2,12911317]
[32,"TOP2A","MITOXANTRONE","inhibitor",13,"10451375;11004693;18687447; 11752352;9631585;9494516;11278845; 9426516"]
[33,"TOP2A","LOMEFLOXACIN","inhibitor",2,11752352]
[34,"TOP2A","EPIRUBICIN","inhibitor",6,"14728934;16234514;17639997"]
[35,"TOP2A","DACTINOMYCIN","-",2,9494516]
[36,"TOP2A","DAUNORUBICIN CITRATE","inhibitor",1,"-"]
[37,"TOP2A","FINAFLOXACIN","inhibitor",2,25808831]
[38,"TOP2A","IDARUBICIN","-",2,"-"]
[39,"TOP2A","HYDROQUINONE","-",2,15833037]
["a The score is the combined number of database sources and PubMed "]
["references supporting a given interaction."]

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