{"text_format":"3","workbook":"xlsx","n_sheets":1,"sheets":["Table S8"],"read":"whole","date_system":"1900"}

{"sheet":"Table S8","index":0,"n_rows":32,"n_cols":10,"rows_kept":32}
["Table S8. List of candidate genes selected from RIP-seq."]
["Geneid","RIP_4h_rep1","Input_4h_rep1","logFC","logCPM","PValue","FDR","GO(GO_term,class,description)","KEGG(KO,pathway,description)"]
["SMAD9",0.580891496,0,6.608567071,1.262548729,0.000667207,0.001675357,"GO:0071407,biological_process,cellular response to organic cyclic compound;GO:0003677,molecular_function,DNA binding;GO:0060395,biological_process,SMAD protein signal transduction;GO:0005667,cellular_component,transcription factor complex;GO:0005737,cellular_component,cytoplasm;GO:0007179,biological_process,transforming growth factor beta receptor signaling pathway;GO:0003700,molecular_function,DNA binding transcription factor activity;GO:0001657,biological_process,ureteric bud development;GO:0005634,cellular_component,nucleus;GO:0006355,biological_process,regulation of transcription, DNA-templated;GO:0030902,biological_process,hindbrain development;GO:0030509,biological_process,BMP signaling pathway;GO:0005654,cellular_component,nucleoplasm;GO:0005622,cellular_component,intracellular;GO:0030901,biological_process,midbrain development;GO:0005829,cellular_component,cytosol;GO:0060348,biological_process,bone development;GO:0006468,biological_process,protein phosphorylation;GO:0051216,biological_process,cartilage development;GO:0006351,biological_process,transcription, DNA-templated","-"]
["ITGA1",0.140690596,0,6.264670196,1.007565613,0.002421289,0.005369716,"GO:0008305,cellular_component,integrin complex;GO:0009986,cellular_component,cell surface;GO:0007155,biological_process,cell adhesion;GO:0009897,cellular_component,external side of plasma membrane;GO:0007160,biological_process,cell-matrix adhesion;GO:0016020,cellular_component,membrane;GO:0008285,biological_process,negative regulation of cell proliferation;GO:0042059,biological_process,negative regulation of epidermal growth factor receptor signaling pathway;GO:0019903,molecular_function,protein phosphatase binding;GO:0034665,cellular_component,integrin alpha1-beta1 complex;GO:0030593,biological_process,neutrophil chemotaxis;GO:0098639,molecular_function,collagen binding involved in cell-matrix adhesion;GO:0016021,cellular_component,integral component of membrane;GO:0045178,cellular_component,basal part of cell;GO:0032516,biological_process,positive regulation of phosphoprotein phosphatase activity;GO:0007229,biological_process,integrin-mediated signaling pathway;GO:0005925,cellular_component,focal adhesion;GO:0045123,biological_process,cellular extravasation","K06480,ko04151,PI3K-Akt signaling pathway;K06480,ko05414,Dilated cardiomyopathy;K06480,ko04810,Regulation of actin cytoskeleton;K06480,ko04512,ECM-receptor interaction;K06480,ko04510,Focal adhesion;K06480,ko04640,Hematopoietic cell lineage;K06480,ko05412,Arrhythmogenic right ventricular cardiomyopathy (ARVC);K06480,ko05410,Hypertrophic cardiomyopathy (HCM)"]
["SMAD7",0.964762237,0.088749579,3.312126892,1.417264779,0.009611236,0.018404761,"GO:0031397,biological_process,negative regulation of protein ubiquitination;GO:0034629,biological_process,cellular protein-containing complex localization;GO:0060389,biological_process,pathway-restricted SMAD protein phosphorylation;GO:0033137,biological_process,negative regulation of peptidyl-serine phosphorylation;GO:0007179,biological_process,transforming growth factor beta receptor signaling pathway;GO:0055117,biological_process,regulation of cardiac muscle contraction;GO:0005518,molecular_function,collagen binding;GO:0000122,biological_process,negative regulation of transcription by RNA polymerase II;GO:0006355,biological_process,regulation of transcription, DNA-templated;GO:0055010,biological_process,ventricular cardiac muscle tissue morphogenesis;GO:0005886,cellular_component,plasma membrane;GO:0006351,biological_process,transcription, DNA-templated;GO:0022409,biological_process,positive regulation of cell-cell adhesion;GO:0043433,biological_process,negative regulation of DNA binding transcription factor activity;GO:0005634,cellular_component,nucleus;GO:0005913,cellular_component,cell-cell adherens junction;GO:0050821,biological_process,protein stabilization;GO:0031625,molecular_function,ubiquitin protein ligase binding;GO:0032436,biological_process,positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0003700,molecular_function,DNA binding transcription factor activity;GO:0048185,molecular_function,activin binding;GO:0001650,cellular_component,fibrillar center;GO:0008013,molecular_function,beta-catenin binding;GO:2000317,biological_process,negative regulation of T-helper 17 type immune response;GO:0005813,cellular_component,centrosome;GO:0005829,cellular_component,cytosol;GO:0001657,biological_process,ureteric bud development;GO:0030512,biological_process,negative regulation of transforming growth factor beta receptor signaling pathway;GO:0060412,biological_process,ventricular septum morphogenesis;GO:0060394,biological_process,negative regulation of pathway-restricted SMAD protein phosphorylation;GO:0003677,molecular_function,DNA binding;GO:0002725,biological_process,negative regulation of T cell cytokine production;GO:0048844,biological_process,artery morphogenesis;GO:0071560,biological_process,cellular response to transforming growth factor beta stimulus;GO:0034616,biological_process,response to laminar fluid shear stress;GO:0030617,molecular_function,transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity;GO:0034333,biological_process,adherens junction assembly;GO:0034713,molecular_function,type I transforming growth factor beta receptor binding;GO:0051444,biological_process,negative regulation of ubiquitin-protein transferase activity;GO:0005654,cellular_component,nucleoplasm;GO:2000320,biological_process,negative regulation of T-helper 17 cell differentiation;GO:0010717,biological_process,regulation of epithelial to mesenchymal transition;GO:0005667,cellular_component,transcription factor complex;GO:0030514,biological_process,negative regulation of BMP signaling pathway;GO:0010944,biological_process,negative regulation of transcription by competitive promoter binding;GO:0016342,cellular_component,catenin complex;GO:0005737,cellular_component,cytoplasm;GO:1990830,biological_process,cellular response to leukemia inhibitory factor;GO:0031398,biological_process,positive regulation of protein ubiquitination;GO:0005622,cellular_component,intracellular;GO:0044212,molecular_function,transcription regulatory region DNA binding;GO:0032925,biological_process,regulation of activin receptor signaling pathway;GO:0010801,biological_process,negative regulation of peptidyl-threonine phosphorylation;GO:0070411,molecular_function,I-SMAD binding","-","`"]
["BCL2",0.948629565,0.139253483,2.742577574,2.864384536,{"v":6.24e-06,"d":"6.24E-06"},{"v":2.48E-5,"d":"2.48E-05"},"GO:0031103,biological_process,axon regeneration;GO:0051607,biological_process,defense response to virus;GO:0014031,biological_process,mesenchymal cell development;GO:0033138,biological_process,positive regulation of peptidyl-serine phosphorylation;GO:2000134,biological_process,negative regulation of G1/S transition of mitotic cell cycle;GO:0050790,biological_process,regulation of catalytic activity;GO:0046982,molecular_function,protein heterodimerization activity;GO:0032469,biological_process,endoplasmic reticulum calcium ion homeostasis;GO:0010507,biological_process,negative regulation of autophagy;GO:0005634,cellular_component,nucleus;GO:0030336,biological_process,negative regulation of cell migration;GO:0043496,biological_process,regulation of protein homodimerization activity;GO:0031625,molecular_function,ubiquitin protein ligase binding;GO:0048546,biological_process,digestive tract morphogenesis;GO:0001657,biological_process,ureteric bud development;GO:0008637,biological_process,apoptotic mitochondrial changes;GO:0051721,molecular_function,protein phosphatase 2A binding;GO:0048743,biological_process,positive regulation of skeletal muscle fiber development;GO:0001822,biological_process,kidney development;GO:0042149,biological_process,cellular response to glucose starvation;GO:0050853,biological_process,B cell receptor signaling pathway;GO:0030097,biological_process,hemopoiesis;GO:0040018,biological_process,positive regulation of multicellular organism growth;GO:0010559,biological_process,regulation of glycoprotein biosynthetic process;GO:0031966,cellular_component,mitochondrial membrane;GO:0010224,biological_process,response to UV-B;GO:0014042,biological_process,positive regulation of neuron maturation;GO:0048070,biological_process,regulation of developmental pigmentation;GO:2000378,biological_process,negative regulation of reactive oxygen species metabolic process;GO:0043029,biological_process,T cell homeostasis;GO:0001503,biological_process,ossification;GO:0048599,biological_process,oocyte development;GO:0002931,biological_process,response to ischemia;GO:0031069,biological_process,hair follicle morphogenesis;GO:0048538,biological_process,thymus development;GO:0070059,biological_process,intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0048536,biological_process,spleen development;GO:0018107,biological_process,peptidyl-threonine phosphorylation;GO:0048545,biological_process,response to steroid hormone;GO:0010332,biological_process,response to gamma radiation;GO:0051434,molecular_function,BH3 domain binding;GO:0001541,biological_process,ovarian follicle development;GO:0007409,biological_process,axonogenesis;GO:0040007,biological_process,growth;GO:0032991,cellular_component,protein-containing complex;GO:0098609,biological_process,cell-cell adhesion;GO:0045069,biological_process,regulation of viral genome replication;GO:0030217,biological_process,T cell differentiation;GO:0005783,cellular_component,endoplasmic reticulum;GO:0008134,molecular_function,transcription factor binding;GO:0007569,biological_process,cell aging;GO:0009887,biological_process,animal organ morphogenesis;GO:2000811,biological_process,negative regulation of anoikis;GO:0018105,biological_process,peptidyl-serine phosphorylation;GO:0051881,biological_process,regulation of mitochondrial membrane potential;GO:0002260,biological_process,lymphocyte homeostasis;GO:0001662,biological_process,behavioral fear response;GO:0097192,biological_process,extrinsic apoptotic signaling pathway in absence of ligand;GO:0071310,biological_process,cellular response to organic substance;GO:0006808,biological_process,regulation of nitrogen utilization;GO:0046930,cellular_component,pore complex;GO:0005739,cellular_component,mitochondrion;GO:0042493,biological_process,response to drug;GO:0005741,cellular_component,mitochondrial outer membrane;GO:0003014,biological_process,renal system process;GO:0006874,biological_process,cellular calcium ion homeostasis;GO:0048589,biological_process,developmental growth;GO:0043375,biological_process,CD8-positive, alpha-beta T cell lineage commitment;GO:0010468,biological_process,regulation of gene expression;GO:0071456,biological_process,cellular response to hypoxia;GO:0006974,biological_process,cellular response to DNA damage stimulus;GO:0008284,biological_process,positive regulation of cell proliferation;GO:0005622,cellular_component,intracellular;GO:0051726,biological_process,regulation of cell cycle;GO:0032848,biological_process,negative regulation of cellular pH reduction;GO:0000209,biological_process,protein polyubiquitination;GO:0043473,biological_process,pigmentation;GO:0045930,biological_process,negative regulation of mitotic cell cycle;GO:2001234,biological_process,negative regulation of apoptotic signaling pathway;GO:0035265,biological_process,organ growth;GO:0043067,biological_process,regulation of programmed cell death;GO:0034097,biological_process,response to cytokine;GO:0010506,biological_process,regulation of autophagy;GO:0046671,biological_process,negative regulation of retinal cell programmed cell death;GO:0045636,biological_process,positive regulation of melanocyte differentiation;GO:0042803,molecular_function,protein homodimerization activity;GO:0032835,biological_process,glomerulus development;GO:0010523,biological_process,negative regulation of calcium ion transport into cytosol;GO:0006470,biological_process,protein dephosphorylation;GO:0008584,biological_process,male gonad development;GO:0048087,biological_process,positive regulation of developmental pigmentation;GO:0035094,biological_process,response to nicotine;GO:0001836,biological_process,release of cytochrome c from mitochondria;GO:0030318,biological_process,melanocyte differentiation;GO:0022612,biological_process,gland morphogenesis;GO:0001656,biological_process,metanephros development;GO:0030307,biological_process,positive regulation of cell growth;GO:0051402,biological_process,neuron apoptotic process;GO:0043565,molecular_function,sequence-specific DNA binding;GO:0043085,biological_process,positive regulation of catalytic activity;GO:0048873,biological_process,homeostasis of number of cells within a tissue;GO:0019903,molecular_function,protein phosphatase binding;GO:0006979,biological_process,response to oxidative stress;GO:0031965,cellular_component,nuclear membrane;GO:0005829,cellular_component,cytosol;GO:0048041,biological_process,focal adhesion assembly;GO:0072593,biological_process,reactive oxygen species metabolic process;GO:0032880,biological_process,regulation of protein localization;GO:0048066,biological_process,developmental pigmentation;GO:0030183,biological_process,B cell differentiation;GO:0001952,biological_process,regulation of cell-matrix adhesion;GO:0002320,biological_process,lymphoid progenitor cell differentiation;GO:0033689,biological_process,negative regulation of osteoblast proliferation;GO:0043524,biological_process,negative regulation of neuron apoptotic process;GO:0002520,biological_process,immune system development;GO:0033033,biological_process,negative regulation of myeloid cell apoptotic process;GO:0016021,cellular_component,integral component of membrane;GO:0001782,biological_process,B cell homeostasis;GO:0051924,biological_process,regulation of calcium ion transport;GO:0008630,biological_process,intrinsic apoptotic signaling pathway in response to DNA damage;GO:0002360,biological_process,T cell lineage commitment;GO:0008285,biological_process,negative regulation of cell proliferation;GO:0006915,biological_process,apoptotic process;GO:0001776,biological_process,leukocyte homeostasis;GO:0030308,biological_process,negative regulation of cell growth;GO:0008631,biological_process,intrinsic apoptotic signaling pathway in response to oxidative stress;GO:0005789,cellular_component,endoplasmic reticulum membrane;GO:0000902,biological_process,cell morphogenesis;GO:0043066,biological_process,negative regulation of apoptotic process;GO:0005737,cellular_component,cytoplasm;GO:0048753,biological_process,pigment granule organization;GO:0002020,molecular_function,protease binding;GO:0051384,biological_process,response to glucocorticoid;GO:0042981,biological_process,regulation of apoptotic process;GO:0042542,biological_process,response to hydrogen peroxide;GO:0046902,biological_process,regulation of mitochondrial membrane permeability;GO:0009636,biological_process,response to toxic substance;GO:0031647,biological_process,regulation of protein stability;GO:0001658,biological_process,branching involved in ureteric bud morphogenesis;GO:0042802,molecular_function,identical protein binding;GO:0021747,biological_process,cochlear nucleus development;GO:0002326,biological_process,B cell lineage commitment;GO:0030279,biological_process,negative regulation of ossification;GO:0042100,biological_process,B cell proliferation;GO:0010039,biological_process,response to iron ion;GO:0033077,biological_process,T cell differentiation in thymus;GO:0016020,cellular_component,membrane;GO:0009791,biological_process,post-embryonic development;GO:2001240,biological_process,negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0005654,cellular_component,nucleoplasm;GO:0043209,cellular_component,myelin sheath;GO:0015267,molecular_function,channel activity;GO:0055085,biological_process,transmembrane transport;GO:0008283,biological_process,cell proliferation;GO:0008625,biological_process,extrinsic apoptotic signaling pathway via death domain receptors;GO:0016248,molecular_function,channel inhibitor activity;GO:0030890,biological_process,positive regulation of B cell proliferation;GO:0022898,biological_process,regulation of transmembrane transporter activity;GO:2001243,biological_process,negative regulation of intrinsic apoptotic signaling pathway;GO:0043583,biological_process,ear development;GO:0007015,biological_process,actin filament organization;GO:0014911,biological_process,positive regulation of smooth muscle cell migration;GO:0043497,biological_process,regulation of protein heterodimerization activity;GO:0006582,biological_process,melanin metabolic process","K02161,ko05222,Small cell lung cancer;K02161,ko05210,Colorectal cancer;K02161,ko04141,Protein processing in endoplasmic reticulum;K02161,ko01524,Platinum drug resistance;K02161,ko04725,Cholinergic synapse;K02161,ko05169,Epstein-Barr virus infection;K02161,ko01521,EGFR tyrosine kinase inhibitor resistance;K02161,ko04210,Apoptosis;K02161,ko04933,AGE-RAGE signaling pathway in diabetic complications;K02161,ko05206,MicroRNAs in cancer;K02161,ko05215,Prostate cancer;K02161,ko05145,Toxoplasmosis;K02161,ko04066,HIF-1 signaling pathway;K02161,ko04071,Sphingolipid signaling pathway;K02161,ko04722,Neurotrophin signaling pathway;K02161,ko05161,Hepatitis B;K02161,ko04064,NF-kappa B signaling pathway;K02161,ko04215,Apoptosis - multiple species;K02161,ko05200,Pathways in cancer;K02161,ko04261,Adrenergic signaling in cardiomyocytes;K02161,ko04151,PI3K-Akt signaling pathway;K02161,ko01522,Endocrine resistance;K02161,ko04510,Focal adhesion;K02161,ko04340,Hedgehog signaling pathway;K02161,ko05152,Tuberculosis;K02161,ko04630,Jak-STAT signaling pathway;K02161,ko05014,Amyotrophic lateral sclerosis (ALS)"]
["MTOR-AS1",4.668285949,0.858881901,2.382382726,1.492720732,0.026470701,0.04485081,"GO:0007584,biological_process,response to nutrient;GO:0031641,biological_process,regulation of myelination;GO:0003007,biological_process,heart morphogenesis;GO:0051534,-,-;GO:0055006,biological_process,cardiac cell development;GO:0051896,biological_process,regulation of protein kinase B signaling;GO:0001932,biological_process,regulation of protein phosphorylation;GO:0010592,biological_process,positive regulation of lamellipodium assembly;GO:0006207,biological_process,'de novo' pyrimidine nucleobase biosynthetic process;GO:0038202,biological_process,TORC1 signaling;GO:0071233,biological_process,cellular response to leucine;GO:0032868,biological_process,response to insulin;GO:0035264,biological_process,multicellular organism growth;GO:0048714,biological_process,positive regulation of oligodendrocyte differentiation;GO:0031529,biological_process,ruffle organization;GO:0009267,biological_process,cellular response to starvation;GO:0030030,biological_process,cell projection organization;GO:0004672,molecular_function,protein kinase activity;GO:0001156,molecular_function,TFIIIC-class transcription factor binding;GO:0043200,biological_process,response to amino acid;GO:0010507,biological_process,negative regulation of autophagy;GO:0005634,cellular_component,nucleus;GO:0008361,biological_process,regulation of cell size;GO:0032956,biological_process,regulation of actin cytoskeleton organization;GO:0016301,molecular_function,kinase activity;GO:0071456,biological_process,cellular response to hypoxia;GO:0001558,biological_process,regulation of cell growth;GO:0007281,biological_process,germ cell development;GO:0016605,cellular_component,PML body;GO:0005737,cellular_component,cytoplasm;GO:0045945,biological_process,positive regulation of transcription by RNA polymerase III;GO:0001030,molecular_function,RNA polymerase III type 1 promoter DNA binding;GO:0055013,biological_process,cardiac muscle cell development;GO:0044877,molecular_function,protein-containing complex binding;GO:0043022,molecular_function,ribosome binding;GO:0043087,biological_process,regulation of GTPase activity;GO:0005524,molecular_function,ATP binding;GO:0046889,biological_process,positive regulation of lipid biosynthetic process;GO:0016310,biological_process,phosphorylation;GO:0005829,cellular_component,cytosol;GO:0050882,biological_process,voluntary musculoskeletal movement;GO:0042802,molecular_function,identical protein binding;GO:1903691,biological_process,positive regulation of wound healing, spreading of epidermal cells;GO:0004674,molecular_function,protein serine/threonine kinase activity;GO:0031931,cellular_component,TORC1 complex;GO:0031929,biological_process,TOR signaling;GO:0010718,biological_process,positive regulation of epithelial to mesenchymal transition;GO:0010628,biological_process,positive regulation of gene expression;GO:0030425,cellular_component,dendrite;GO:0018105,biological_process,peptidyl-serine phosphorylation;GO:0001032,molecular_function,RNA polymerase III type 3 promoter DNA binding;GO:0090559,biological_process,regulation of membrane permeability;GO:0016740,molecular_function,transferase activity;GO:0045792,biological_process,negative regulation of cell size;GO:0031932,cellular_component,TORC2 complex;GO:0010831,biological_process,positive regulation of myotube differentiation;GO:0060048,biological_process,cardiac muscle contraction;GO:0045670,biological_process,regulation of osteoclast differentiation;GO:0003179,biological_process,heart valve morphogenesis;GO:0016020,cellular_component,membrane;GO:0009791,biological_process,post-embryonic development;GO:0031669,biological_process,cellular response to nutrient levels;GO:0006468,biological_process,protein phosphorylation;GO:0000166,molecular_function,nucleotide binding;GO:0045859,biological_process,regulation of protein kinase activity;GO:0030838,biological_process,positive regulation of actin filament polymerization;GO:0051549,biological_process,positive regulation of keratinocyte migration;GO:0006112,biological_process,energy reserve metabolic process;GO:0012505,cellular_component,endomembrane system;GO:0051496,biological_process,positive regulation of stress fiber assembly;GO:0016242,biological_process,negative regulation of macroautophagy;GO:0001031,molecular_function,RNA polymerase III type 2 promoter DNA binding;GO:0048738,biological_process,cardiac muscle tissue development;GO:0005764,cellular_component,lysosome;GO:0046777,biological_process,protein autophosphorylation;GO:0071230,biological_process,cellular response to amino acid stimulus;GO:0050731,biological_process,positive regulation of peptidyl-tyrosine phosphorylation;GO:0018107,biological_process,peptidyl-threonine phosphorylation;GO:1901838,biological_process,positive regulation of transcription of nucleolar large rRNA by RNA polymerase I;GO:0051219,molecular_function,phosphoprotein binding;GO:0001934,biological_process,positive regulation of protein phosphorylation;GO:1990253,biological_process,cellular response to leucine starvation;GO:0045727,biological_process,positive regulation of translation;GO:0034198,biological_process,cellular response to amino acid starvation","K07203,ko01522,Endocrine resistance;K07203,ko04139,Regulation of mitophagy - yeast;K07203,ko05215,Prostate cancer;K07203,ko04072,Phospholipase D signaling pathway;K07203,ko04151,PI3K-Akt signaling pathway;K07203,ko01521,EGFR tyrosine kinase inhibitor resistance;K07203,ko05230,Central carbon metabolism in cancer;K07203,ko04920,Adipocytokine signaling pathway;K07203,ko04919,Thyroid hormone signaling pathway;K07203,ko04012,ErbB signaling pathway;K07203,ko05214,Glioma;K07203,ko04212,Longevity regulating pathway - worm;K07203,ko04213,Longevity regulating pathway - multiple species;K07203,ko04152,AMPK signaling pathway;K07203,ko04910,Insulin signaling pathway;K07203,ko04150,mTOR signaling pathway;K07203,ko05206,MicroRNAs in cancer;K07203,ko05221,Acute myeloid leukemia;K07203,ko04930,Type II diabetes mellitus;K07203,ko04630,Jak-STAT signaling pathway;K07203,ko05231,Choline metabolism in cancer;K07203,ko04066,HIF-1 signaling pathway;K07203,ko05205,Proteoglycans in cancer;K07203,ko04211,Longevity regulating pathway;K07203,ko04931,Insulin resistance;K07203,ko05200,Pathways in cancer"]
["EGFR",440.6232334,92.08413979,2.258486875,11.70281639,{"v":7.9e-26,"d":"7.90E-26"},{"v":1.59e-23,"d":"1.59E-23"},"GO:0016301,molecular_function,kinase activity;GO:0018108,biological_process,peptidyl-tyrosine phosphorylation;GO:0035556,biological_process,intracellular signal transduction;GO:0004716,molecular_function,signal transducer, downstream of receptor, with protein tyrosine kinase activity;GO:0016020,cellular_component,membrane;GO:0016740,molecular_function,transferase activity;GO:0004714,molecular_function,transmembrane receptor protein tyrosine kinase activity;GO:0005524,molecular_function,ATP binding;GO:0004713,molecular_function,protein tyrosine kinase activity;GO:0007169,biological_process,transmembrane receptor protein tyrosine kinase signaling pathway;GO:0004672,molecular_function,protein kinase activity;GO:0005622,cellular_component,intracellular;GO:0006468,biological_process,protein phosphorylation;GO:0000166,molecular_function,nucleotide binding;GO:0016310,biological_process,phosphorylation;GO:0016021,cellular_component,integral component of membrane;GO:0023014,biological_process,signal transduction by protein phosphorylation","-"]
["MAST2",9.767308248,2.038277112,2.258166527,5.571766957,{"v":5.64e-15,"d":"5.64E-15"},{"v":1.73e-13,"d":"1.73E-13"},"GO:0004672,molecular_function,protein kinase activity;GO:0016301,molecular_function,kinase activity;GO:0006468,biological_process,protein phosphorylation;GO:0016740,molecular_function,transferase activity;GO:0016310,biological_process,phosphorylation;GO:0004674,molecular_function,protein serine/threonine kinase activity;GO:0045075,biological_process,regulation of interleukin-12 biosynthetic process;GO:0000166,molecular_function,nucleotide binding;GO:0005524,molecular_function,ATP binding;GO:0000287,molecular_function,magnesium ion binding","-"]
["MAP4",11.79116829,2.543596308,2.211740961,6.757559595,{"v":8.48e-19,"d":"8.48E-19"},{"v":5.5E-17,"d":"5.50E-17"},"GO:0005874,cellular_component,microtubule;GO:0005737,cellular_component,cytoplasm;GO:0005856,cellular_component,cytoskeleton;GO:0005886,cellular_component,plasma membrane;GO:0015631,molecular_function,tubulin binding;GO:0005829,cellular_component,cytosol;GO:0015630,cellular_component,microtubule cytoskeleton","-"]
["MALT1",2.188572768,0.483190334,2.171975512,3.948665153,{"v":5.94e-08,"d":"5.94E-08"},{"v":3.68e-07,"d":"3.68E-07"},"GO:0004197,molecular_function,cysteine-type endopeptidase activity;GO:0006508,biological_process,proteolysis;GO:0051092,biological_process,positive regulation of NF-kappaB transcription factor activity","K07369,ko04662,B cell receptor signaling pathway;K07369,ko04064,NF-kappa B signaling pathway;K07369,ko04660,T cell receptor signaling pathway;K07369,ko05152,Tuberculosis"]
["EGFR-AS1",59.74585266,13.31205728,2.165072407,6.694724174,{"v":6.38e-18,"d":"6.38E-18"},3.52E-16,"GO:0018108,biological_process,peptidyl-tyrosine phosphorylation;GO:0035556,biological_process,intracellular signal transduction;GO:0000166,molecular_function,nucleotide binding;GO:0005622,cellular_component,intracellular;GO:0007169,biological_process,transmembrane receptor protein tyrosine kinase signaling pathway;GO:0004714,molecular_function,transmembrane receptor protein tyrosine kinase activity;GO:0004672,molecular_function,protein kinase activity;GO:0016020,cellular_component,membrane;GO:0006468,biological_process,protein phosphorylation;GO:0004716,molecular_function,signal transducer, downstream of receptor, with protein tyrosine kinase activity;GO:0005524,molecular_function,ATP binding;GO:0016021,cellular_component,integral component of membrane;GO:0023014,biological_process,signal transduction by protein phosphorylation","-"]
["SNAI2",27.05505599,6.030615554,2.162721267,5.277551839,8.86e-13,1.63e-11,"GO:2000810,biological_process,regulation of bicellular tight junction assembly;GO:0043473,biological_process,pigmentation;GO:0043518,biological_process,negative regulation of DNA damage response, signal transduction by p53 class mediator;GO:0001078,molecular_function,transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003676,molecular_function,nucleic acid binding;GO:0035414,-,-;GO:0070563,biological_process,negative regulation of vitamin D receptor signaling pathway;GO:0000122,biological_process,negative regulation of transcription by RNA polymerase II;GO:1902230,biological_process,negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage;GO:0001649,biological_process,osteoblast differentiation;GO:0090090,biological_process,negative regulation of canonical Wnt signaling pathway;GO:0001837,biological_process,epithelial to mesenchymal transition;GO:0010839,biological_process,negative regulation of keratinocyte proliferation;GO:0005634,cellular_component,nucleus;GO:2000811,biological_process,negative regulation of anoikis;GO:0032331,biological_process,negative regulation of chondrocyte differentiation;GO:0014032,biological_process,neural crest cell development;GO:0032642,biological_process,regulation of chemokine production;GO:0007605,biological_process,sensory perception of sound;GO:0035921,biological_process,desmosome disassembly;GO:0010957,biological_process,negative regulation of vitamin D biosynthetic process;GO:0071364,biological_process,cellular response to epidermal growth factor stimulus;GO:0000790,cellular_component,nuclear chromatin;GO:0030335,biological_process,positive regulation of cell migration;GO:1900387,biological_process,negative regulation of cell-cell adhesion by negative regulation of transcription from RNA polymerase II promoter;GO:0043565,molecular_function,sequence-specific DNA binding;GO:0060070,biological_process,canonical Wnt signaling pathway;GO:0007219,biological_process,Notch signaling pathway;GO:0045667,biological_process,regulation of osteoblast differentiation","K05706,ko04520,Adherens junction;K05706,ko04390,Hippo signaling pathway"]
["MYC",49.21699779,11.0276601,2.156866385,6.515382778,2.57E-17,{"v":1.27e-15,"d":"1.27E-15"},"GO:0001541,biological_process,ovarian follicle development;GO:0044344,biological_process,cellular response to fibroblast growth factor stimulus;GO:0046983,molecular_function,protein dimerization activity;GO:0048661,biological_process,positive regulation of smooth muscle cell proliferation;GO:0046982,molecular_function,protein heterodimerization activity;GO:0060252,biological_process,positive regulation of glial cell proliferation;GO:0010918,biological_process,positive regulation of mitochondrial membrane potential;GO:0021854,biological_process,hypothalamus development;GO:0006006,biological_process,glucose metabolic process;GO:0000122,biological_process,negative regulation of transcription by RNA polymerase II;GO:0006355,biological_process,regulation of transcription, DNA-templated;GO:1904628,biological_process,cellular response to phorbol 13-acetate 12-myristate;GO:0006352,biological_process,DNA-templated transcription, initiation;GO:0043388,biological_process,positive regulation of DNA binding;GO:0045471,biological_process,response to ethanol;GO:0071346,biological_process,cellular response to interferon-gamma;GO:0044330,biological_process,canonical Wnt signaling pathway involved in positive regulation of wound healing;GO:0003677,molecular_function,DNA binding;GO:0006848,biological_process,pyruvate transport;GO:0071322,biological_process,cellular response to carbohydrate stimulus;GO:0005634,cellular_component,nucleus;GO:0030728,biological_process,ovulation;GO:0071378,biological_process,cellular response to growth hormone stimulus;GO:0071966,biological_process,fungal-type cell wall polysaccharide metabolic process;GO:0006865,biological_process,amino acid transport;GO:0048146,biological_process,positive regulation of fibroblast proliferation;GO:0005737,cellular_component,cytoplasm;GO:0003700,molecular_function,DNA binding transcription factor activity;GO:0060548,biological_process,negative regulation of cell death;GO:0001701,biological_process,in utero embryonic development;GO:0045893,biological_process,positive regulation of transcription, DNA-templated;GO:0006366,biological_process,transcription by RNA polymerase II;GO:0046325,biological_process,negative regulation of glucose import;GO:0071364,biological_process,cellular response to epidermal growth factor stimulus;GO:0005739,cellular_component,mitochondrion;GO:1903841,biological_process,cellular response to arsenite(3-);GO:0045787,biological_process,positive regulation of cell cycle;GO:1903862,biological_process,positive regulation of oxidative phosphorylation;GO:1904385,biological_process,cellular response to angiotensin;GO:0032355,biological_process,response to estradiol;GO:0046722,biological_process,lactic acid secretion;GO:0071391,biological_process,cellular response to estrogen stimulus;GO:0002082,biological_process,regulation of oxidative phosphorylation;GO:0000320,biological_process,re-entry into mitotic cell cycle;GO:0071300,biological_process,cellular response to retinoic acid;GO:0035690,biological_process,cellular response to drug;GO:0043565,molecular_function,sequence-specific DNA binding;GO:1904586,biological_process,cellular response to putrescine;GO:0045821,biological_process,positive regulation of glycolytic process;GO:2001171,biological_process,positive regulation of ATP biosynthetic process;GO:0097421,biological_process,liver regeneration;GO:0045944,biological_process,positive regulation of transcription by RNA polymerase II;GO:0071407,biological_process,cellular response to organic cyclic compound;GO:0045023,biological_process,G0 to G1 transition;GO:0008284,biological_process,positive regulation of cell proliferation;GO:0010629,biological_process,negative regulation of gene expression;GO:0032869,biological_process,cellular response to insulin stimulus;GO:0071409,biological_process,cellular response to cycloheximide;GO:1901857,biological_process,positive regulation of cellular respiration;GO:0036120,biological_process,cellular response to platelet-derived growth factor stimulus;GO:1990859,biological_process,cellular response to endothelin;GO:0005654,cellular_component,nucleoplasm;GO:0007346,biological_process,regulation of mitotic cell cycle;GO:1990646,biological_process,cellular response to prolactin;GO:0071347,biological_process,cellular response to interleukin-1;GO:0005730,cellular_component,nucleolus;GO:0008283,biological_process,cell proliferation;GO:1990858,biological_process,cellular response to lectin;GO:0044752,biological_process,response to human chorionic gonadotropin;GO:1904620,biological_process,cellular response to dimethyl sulfoxide;GO:0003690,molecular_function,double-stranded DNA binding;GO:0009611,biological_process,response to wounding;GO:0019087,biological_process,transformation of host cell by virus;GO:0071394,biological_process,cellular response to testosterone stimulus;GO:0007007,biological_process,inner mitochondrial membrane organization;GO:0008134,molecular_function,transcription factor binding;GO:0009812,biological_process,flavonoid metabolic process;GO:0014911,biological_process,positive regulation of smooth muscle cell migration;GO:0071464,biological_process,cellular response to hydrostatic pressure;GO:0006351,biological_process,transcription, DNA-templated","-"]
["SOX9",7.241478382,1.665379645,2.114617022,4.208280184,{"v":1.72e-08,"d":"1.72E-08"},{"v":1.2e-07,"d":"1.20E-07"},"GO:0007283,biological_process,spermatogenesis;GO:0034236,molecular_function,protein kinase A catalytic subunit binding;GO:0003179,biological_process,heart valve morphogenesis;GO:0003705,molecular_function,transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding;GO:0000122,biological_process,negative regulation of transcription by RNA polymerase II;GO:0046982,molecular_function,protein heterodimerization activity;GO:0060350,biological_process,endochondral bone morphogenesis;GO:0007417,biological_process,central nervous system development;GO:0071599,biological_process,otic vesicle development;GO:0005634,cellular_component,nucleus;GO:0072289,biological_process,metanephric nephron tubule formation;GO:0014032,biological_process,neural crest cell development;GO:0045732,biological_process,positive regulation of protein catabolic process;GO:0001501,biological_process,skeletal system development;GO:0060532,biological_process,bronchus cartilage development;GO:0060041,biological_process,retina development in camera-type eye;GO:0003700,molecular_function,DNA binding transcription factor activity;GO:0030198,biological_process,extracellular matrix organization;GO:2000794,biological_process,regulation of epithelial cell proliferation involved in lung morphogenesis;GO:0061036,biological_process,positive regulation of cartilage development;GO:1901203,biological_process,positive regulation of extracellular matrix assembly;GO:0071300,biological_process,cellular response to retinoic acid;GO:0032332,biological_process,positive regulation of chondrocyte differentiation;GO:0030879,biological_process,mammary gland development;GO:0045892,biological_process,negative regulation of transcription, DNA-templated;GO:0044798,cellular_component,nuclear transcription factor complex;GO:0000981,molecular_function,RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0005667,cellular_component,transcription factor complex;GO:0032808,biological_process,lacrimal gland development;GO:0003413,biological_process,chondrocyte differentiation involved in endochondral bone morphogenesis;GO:0051216,biological_process,cartilage development;GO:0034504,biological_process,protein localization to nucleus;GO:0001942,biological_process,hair follicle development;GO:0060784,biological_process,regulation of cell proliferation involved in tissue homeostasis;GO:0060009,biological_process,Sertoli cell development;GO:0032991,cellular_component,protein-containing complex;GO:0098609,biological_process,cell-cell adhesion;GO:0008013,molecular_function,beta-catenin binding;GO:1902894,biological_process,negative regulation of pri-miRNA transcription by RNA polymerase II;GO:0071260,biological_process,cellular response to mechanical stimulus;GO:0030916,biological_process,otic vesicle formation;GO:0004672,molecular_function,protein kinase activity;GO:2000020,biological_process,positive regulation of male gonad development;GO:0090090,biological_process,negative regulation of canonical Wnt signaling pathway;GO:0001837,biological_process,epithelial to mesenchymal transition;GO:0035326,molecular_function,enhancer binding;GO:0045165,biological_process,cell fate commitment;GO:2000138,biological_process,positive regulation of cell proliferation involved in heart morphogenesis;GO:0001502,biological_process,cartilage condensation;GO:0006366,biological_process,transcription by RNA polymerase II;GO:0001077,molecular_function,transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0010629,biological_process,negative regulation of gene expression;GO:0048709,biological_process,oligodendrocyte differentiation;GO:0007173,biological_process,epidermal growth factor receptor signaling pathway;GO:0003682,molecular_function,chromatin binding;GO:0060441,biological_process,epithelial tube branching involved in lung morphogenesis;GO:0001708,biological_process,cell fate specification;GO:0072189,biological_process,ureter development;GO:0010628,biological_process,positive regulation of gene expression;GO:0090103,biological_process,cochlea morphogenesis;GO:0002063,biological_process,chondrocyte development;GO:0001228,molecular_function,transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0035019,biological_process,somatic stem cell population maintenance;GO:0030155,biological_process,regulation of cell adhesion;GO:0072193,biological_process,ureter smooth muscle cell differentiation;GO:0019933,biological_process,cAMP-mediated signaling;GO:0008284,biological_process,positive regulation of cell proliferation;GO:0050679,biological_process,positive regulation of epithelial cell proliferation;GO:0000976,molecular_function,transcription regulatory region sequence-specific DNA binding;GO:0065003,biological_process,protein-containing complex assembly;GO:0001894,biological_process,tissue homeostasis;GO:0006334,biological_process,nucleosome assembly;GO:0003188,biological_process,heart valve formation;GO:0070168,biological_process,negative regulation of biomineral tissue development;GO:0030903,biological_process,notochord development;GO:0061145,biological_process,lung smooth muscle development;GO:0060729,biological_process,intestinal epithelial structure maintenance;GO:0030502,biological_process,negative regulation of bone mineralization;GO:0060487,biological_process,lung epithelial cell differentiation;GO:0030857,biological_process,negative regulation of epithelial cell differentiation;GO:0060534,biological_process,trachea cartilage development;GO:0002053,biological_process,positive regulation of mesenchymal cell proliferation;GO:0006355,biological_process,regulation of transcription, DNA-templated;GO:0030850,biological_process,prostate gland development;GO:0001046,molecular_function,core promoter sequence-specific DNA binding;GO:0032331,biological_process,negative regulation of chondrocyte differentiation;GO:0072197,biological_process,ureter morphogenesis;GO:2001054,biological_process,negative regulation of mesenchymal cell apoptotic process;GO:0008584,biological_process,male gonad development;GO:0071364,biological_process,cellular response to epidermal growth factor stimulus;GO:0005654,cellular_component,nucleoplasm;GO:0060221,biological_process,retinal rod cell differentiation;GO:0042127,biological_process,regulation of cell proliferation;GO:0045662,biological_process,negative regulation of myoblast differentiation;GO:0014068,biological_process,positive regulation of phosphatidylinositol 3-kinase signaling;GO:0043565,molecular_function,sequence-specific DNA binding;GO:0097157,molecular_function,pre-mRNA intronic binding;GO:0007010,biological_process,cytoskeleton organization;GO:0045944,biological_process,positive regulation of transcription by RNA polymerase II;GO:0006338,biological_process,chromatin remodeling;GO:0002062,biological_process,chondrocyte differentiation;GO:0097065,biological_process,anterior head development;GO:0007165,biological_process,signal transduction;GO:0030154,biological_process,cell differentiation;GO:0001503,biological_process,ossification;GO:2000741,biological_process,positive regulation of mesenchymal stem cell differentiation;GO:0006357,biological_process,regulation of transcription by RNA polymerase II;GO:0072034,biological_process,renal vesicle induction;GO:0072190,biological_process,ureter urothelium development;GO:0090184,biological_process,positive regulation of kidney development;GO:0002683,biological_process,negative regulation of immune system process;GO:0090190,biological_process,positive regulation of branching involved in ureteric bud morphogenesis;GO:0001934,biological_process,positive regulation of protein phosphorylation;GO:0030238,biological_process,male sex determination;GO:0070371,biological_process,ERK1 and ERK2 cascade;GO:0060174,biological_process,limb bud formation;GO:0001158,molecular_function,enhancer sequence-specific DNA binding;GO:0061046,biological_process,regulation of branching involved in lung morphogenesis;GO:0044212,molecular_function,transcription regulatory region DNA binding;GO:0060512,biological_process,prostate gland morphogenesis;GO:0003170,biological_process,heart valve development;GO:0070384,biological_process,Harderian gland development;GO:0007507,biological_process,heart development;GO:0043066,biological_process,negative regulation of apoptotic process;GO:0045893,biological_process,positive regulation of transcription, DNA-templated;GO:0010564,biological_process,regulation of cell cycle process;GO:0071504,biological_process,cellular response to heparin;GO:0010634,biological_process,positive regulation of epithelial cell migration;GO:0001658,biological_process,branching involved in ureteric bud morphogenesis;GO:0035622,biological_process,intrahepatic bile duct development;GO:0030279,biological_process,negative regulation of ossification;GO:0003677,molecular_function,DNA binding;GO:0072170,biological_process,metanephric tubule development;GO:0061138,biological_process,morphogenesis of a branching epithelium;GO:0060018,biological_process,astrocyte fate commitment;GO:0045595,biological_process,regulation of cell differentiation;GO:0043491,biological_process,protein kinase B signaling;GO:0060008,biological_process,Sertoli cell differentiation;GO:0031018,biological_process,endocrine pancreas development;GO:0048873,biological_process,homeostasis of number of cells within a tissue;GO:0050680,biological_process,negative regulation of epithelial cell proliferation;GO:0019100,biological_process,male germ-line sex determination;GO:0071347,biological_process,cellular response to interleukin-1;GO:0003415,biological_process,chondrocyte hypertrophy;GO:0008285,biological_process,negative regulation of cell proliferation;GO:0071560,biological_process,cellular response to transforming growth factor beta stimulus;GO:0003203,biological_process,endocardial cushion morphogenesis;GO:0007219,biological_process,Notch signaling pathway;GO:0030858,biological_process,positive regulation of epithelial cell differentiation;GO:0046533,biological_process,negative regulation of photoreceptor cell differentiation;GO:0060517,biological_process,epithelial cell proliferation involved in prostatic bud elongation","-"]
["PRMT9",2.127037878,0.489171603,2.101190328,2.599666478,0.000877812,0.002140789,"GO:0035243,molecular_function,protein-arginine omega-N symmetric methyltransferase activity;GO:0019918,biological_process,peptidyl-arginine methylation, to symmetrical-dimethyl arginine;GO:0005737,cellular_component,cytoplasm;GO:0016740,molecular_function,transferase activity;GO:0006479,biological_process,protein methylation;GO:0035246,biological_process,peptidyl-arginine N-methylation;GO:0032259,biological_process,methylation;GO:0016274,molecular_function,protein-arginine N-methyltransferase activity;GO:0006397,biological_process,mRNA processing;GO:0008168,molecular_function,methyltransferase activity","-"]
["INHBA",0.514849749,0.118404039,2.082351493,1.741736692,0.016186198,0.029240254,"GO:0001541,biological_process,ovarian follicle development;GO:0008083,molecular_function,growth factor activity;GO:0001942,biological_process,hair follicle development;GO:0042476,biological_process,odontogenesis;GO:0005102,molecular_function,signaling receptor binding;GO:0043512,cellular_component,inhibin A complex;GO:0048333,biological_process,mesodermal cell differentiation;GO:0045786,biological_process,negative regulation of cell cycle;GO:0030308,biological_process,negative regulation of cell growth;GO:0010862,biological_process,positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0051799,biological_process,negative regulation of hair follicle development;GO:0046880,biological_process,regulation of follicle-stimulating hormone secretion;GO:0005576,cellular_component,extracellular region;GO:0017046,molecular_function,peptide hormone binding;GO:0000082,biological_process,G1/S transition of mitotic cell cycle;GO:0060021,biological_process,roof of mouth development;GO:0005179,molecular_function,hormone activity;GO:0010469,biological_process,regulation of signaling receptor activity;GO:0008584,biological_process,male gonad development;GO:0045893,biological_process,positive regulation of transcription, DNA-templated;GO:0001707,biological_process,mesoderm formation;GO:0061029,biological_process,eyelid development in camera-type eye;GO:2001241,biological_process,positive regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0002244,biological_process,hematopoietic progenitor cell differentiation;GO:0043509,cellular_component,activin A complex;GO:0005615,cellular_component,extracellular space;GO:0042802,molecular_function,identical protein binding;GO:0042493,biological_process,response to drug;GO:0032924,biological_process,activin receptor signaling pathway;GO:0010628,biological_process,positive regulation of gene expression;GO:0060395,biological_process,SMAD protein signal transduction;GO:0042981,biological_process,regulation of apoptotic process;GO:0070699,molecular_function,type II activin receptor binding;GO:0021773,biological_process,striatal medium spiny neuron differentiation;GO:0060279,biological_process,positive regulation of ovulation;GO:0045944,biological_process,positive regulation of transcription by RNA polymerase II;GO:0045648,biological_process,positive regulation of erythrocyte differentiation;GO:0042701,biological_process,progesterone secretion;GO:0042541,biological_process,hemoglobin biosynthetic process;GO:0032270,biological_process,positive regulation of cellular protein metabolic process;GO:0035987,biological_process,endodermal cell differentiation;GO:0007050,biological_process,cell cycle arrest;GO:0006357,biological_process,regulation of transcription by RNA polymerase II;GO:0005125,molecular_function,cytokine activity;GO:0008285,biological_process,negative regulation of cell proliferation;GO:0048471,cellular_component,perinuclear region of cytoplasm;GO:0005160,molecular_function,transforming growth factor beta receptor binding;GO:0048468,biological_process,cell development;GO:0097154,biological_process,GABAergic neuron differentiation;GO:0043408,biological_process,regulation of MAPK cascade;GO:0097191,biological_process,extrinsic apoptotic signaling pathway","K04667,ko04350,TGF-beta signaling pathway;K04667,ko04550,Signaling pathways regulating pluripotency of stem cells;K04667,ko04060,Cytokine-cytokine receptor interaction"]
["JAK1",28.08021664,6.639373274,2.079531504,6.79099715,{"v":3.74e-17,"d":"3.74E-17"},{"v":1.8e-15,"d":"1.80E-15"},"GO:0038083,biological_process,peptidyl-tyrosine autophosphorylation;GO:0005102,molecular_function,signaling receptor binding;GO:0030154,biological_process,cell differentiation;GO:0005856,cellular_component,cytoskeleton;GO:0004672,molecular_function,protein kinase activity;GO:0005634,cellular_component,nucleus;GO:0016301,molecular_function,kinase activity;GO:0035556,biological_process,intracellular signal transduction;GO:0005737,cellular_component,cytoplasm;GO:0005524,molecular_function,ATP binding;GO:0042127,biological_process,regulation of cell proliferation;GO:0016310,biological_process,phosphorylation;GO:0007169,biological_process,transmembrane receptor protein tyrosine kinase signaling pathway;GO:0016740,molecular_function,transferase activity;GO:0004715,molecular_function,non-membrane spanning protein tyrosine kinase activity;GO:0004713,molecular_function,protein tyrosine kinase activity;GO:0016020,cellular_component,membrane;GO:0038110,biological_process,interleukin-2-mediated signaling pathway;GO:0006468,biological_process,protein phosphorylation;GO:0000166,molecular_function,nucleotide binding;GO:0019903,molecular_function,protein phosphatase binding;GO:0045087,biological_process,innate immune response;GO:0031625,molecular_function,ubiquitin protein ligase binding;GO:1903672,biological_process,positive regulation of sprouting angiogenesis;GO:0046677,biological_process,response to antibiotic;GO:0031234,cellular_component,extrinsic component of cytoplasmic side of plasma membrane;GO:0016477,biological_process,cell migration","K11217,ko04550,Signaling pathways regulating pluripotency of stem cells;K11217,ko05160,Hepatitis C;K11217,ko05161,Hepatitis B;K11217,ko04151,PI3K-Akt signaling pathway;K11217,ko04380,Osteoclast differentiation;K11217,ko05169,Epstein-Barr virus infection;K11217,ko05140,Leishmaniasis;K11217,ko05162,Measles;K11217,ko05164,Influenza A;K11217,ko05152,Tuberculosis;K11217,ko04630,Jak-STAT signaling pathway;K11217,ko05166,HTLV-I infection;K11217,ko05200,Pathways in cancer;K11217,ko05168,Herpes simplex infection;K11217,ko01521,EGFR tyrosine kinase inhibitor resistance;K11217,ko05212,Pancreatic cancer;K11217,ko05145,Toxoplasmosis;K11217,ko05203,Viral carcinogenesis"]
["MET",9.985538145,2.420585189,2.042279108,5.481915348,1.79E-12,{"v":3.06e-11,"d":"3.06E-11"},"GO:0016301,molecular_function,kinase activity;GO:0018108,biological_process,peptidyl-tyrosine phosphorylation;GO:0007169,biological_process,transmembrane receptor protein tyrosine kinase signaling pathway;GO:0004714,molecular_function,transmembrane receptor protein tyrosine kinase activity;GO:0016310,biological_process,phosphorylation;GO:0004713,molecular_function,protein tyrosine kinase activity;GO:0004672,molecular_function,protein kinase activity;GO:0016740,molecular_function,transferase activity;GO:0016020,cellular_component,membrane;GO:0006468,biological_process,protein phosphorylation;GO:0000166,molecular_function,nucleotide binding;GO:0005524,molecular_function,ATP binding;GO:0016021,cellular_component,integral component of membrane","-"]
["SOX12",15.79648483,3.892330341,2.018823434,5.542442952,1.46E-12,{"v":2.54e-11,"d":"2.54E-11"},"GO:0006366,biological_process,transcription by RNA polymerase II;GO:0003677,molecular_function,DNA binding;GO:0045165,biological_process,cell fate commitment;GO:0006357,biological_process,regulation of transcription by RNA polymerase II;GO:0045944,biological_process,positive regulation of transcription by RNA polymerase II;GO:0006355,biological_process,regulation of transcription, DNA-templated;GO:0001105,molecular_function,RNA polymerase II transcription coactivator activity;GO:0006351,biological_process,transcription, DNA-templated;GO:0005634,cellular_component,nucleus","-"]
["TGFBR2",12.97348158,3.204191852,2.015055877,5.28777102,{"v":1.83e-11,"d":"1.83E-11"},{"v":2.5e-10,"d":"2.50E-10"},"GO:0060389,biological_process,pathway-restricted SMAD protein phosphorylation;GO:0060443,biological_process,mammary gland morphogenesis;GO:0004702,molecular_function,signal transducer, downstream of receptor, with serine/threonine kinase activity;GO:0005886,cellular_component,plasma membrane;GO:0002666,biological_process,positive regulation of T cell tolerance induction;GO:0005026,molecular_function,transforming growth factor beta receptor activity, type II;GO:0045766,biological_process,positive regulation of angiogenesis;GO:0000166,molecular_function,nucleotide binding;GO:0002663,biological_process,positive regulation of B cell tolerance induction;GO:0060463,biological_process,lung lobe morphogenesis;GO:0070723,biological_process,response to cholesterol;GO:0007420,biological_process,brain development;GO:0003181,biological_process,atrioventricular valve morphogenesis;GO:0006915,biological_process,apoptotic process;GO:0001947,biological_process,heart looping;GO:0045121,cellular_component,membrane raft;GO:0032147,biological_process,activation of protein kinase activity;GO:0003274,biological_process,endocardial cushion fusion;GO:0034713,molecular_function,type I transforming growth factor beta receptor binding;GO:0060440,biological_process,trachea formation;GO:0042493,biological_process,response to drug;GO:0002088,biological_process,lens development in camera-type eye;GO:1905007,biological_process,positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation;GO:0051216,biological_process,cartilage development;GO:2000379,biological_process,positive regulation of reactive oxygen species metabolic process;GO:0007179,biological_process,transforming growth factor beta receptor signaling pathway;GO:0046332,molecular_function,SMAD binding;GO:0004672,molecular_function,protein kinase activity;GO:0005524,molecular_function,ATP binding;GO:2000563,biological_process,positive regulation of CD4-positive, alpha-beta T cell proliferation;GO:0018105,biological_process,peptidyl-serine phosphorylation;GO:0040008,biological_process,regulation of growth;GO:0051138,biological_process,positive regulation of NK T cell differentiation;GO:0003148,biological_process,outflow tract septum morphogenesis;GO:0018107,biological_process,peptidyl-threonine phosphorylation;GO:0004674,molecular_function,protein serine/threonine kinase activity;GO:0001569,biological_process,branching involved in blood vessel morphogenesis;GO:0030154,biological_process,cell differentiation;GO:0003214,biological_process,cardiac left ventricle morphogenesis;GO:0010468,biological_process,regulation of gene expression;GO:0050431,molecular_function,transforming growth factor beta binding;GO:0004872,-,-;GO:0003417,biological_process,growth plate cartilage development;GO:0023014,biological_process,signal transduction by protein phosphorylation;GO:0060433,biological_process,bronchus development;GO:0001701,biological_process,in utero embryonic development;GO:0003149,biological_process,membranous septum morphogenesis;GO:0004675,molecular_function,transmembrane receptor protein serine/threonine kinase activity;GO:0007224,biological_process,smoothened signaling pathway;GO:0002053,biological_process,positive regulation of mesenchymal cell proliferation;GO:0003430,biological_process,growth plate cartilage chondrocyte growth;GO:0016310,biological_process,phosphorylation;GO:0060021,biological_process,roof of mouth development;GO:0043235,cellular_component,receptor complex;GO:0016021,cellular_component,integral component of membrane;GO:0007178,biological_process,transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0042127,biological_process,regulation of cell proliferation;GO:0060425,biological_process,lung morphogenesis;GO:0016740,molecular_function,transferase activity;GO:0003186,biological_process,tricuspid valve morphogenesis;GO:0007369,biological_process,gastrulation;GO:0002651,biological_process,positive regulation of tolerance induction to self antigen;GO:0006468,biological_process,protein phosphorylation;GO:0060434,biological_process,bronchus morphogenesis;GO:0030324,biological_process,lung development;GO:0003151,biological_process,outflow tract morphogenesis;GO:0048701,biological_process,embryonic cranial skeleton morphogenesis;GO:0060412,biological_process,ventricular septum morphogenesis;GO:0043011,biological_process,myeloid dendritic cell differentiation;GO:0001570,biological_process,vasculogenesis;GO:0060439,biological_process,trachea morphogenesis;GO:0007507,biological_process,heart development;GO:0010634,biological_process,positive regulation of epithelial cell migration;GO:0010718,biological_process,positive regulation of epithelial to mesenchymal transition;GO:0009897,cellular_component,external side of plasma membrane;GO:0035162,biological_process,embryonic hemopoiesis;GO:0016301,molecular_function,kinase activity;GO:0005024,molecular_function,transforming growth factor beta-activated receptor activity;GO:1990428,biological_process,miRNA transport;GO:0016020,cellular_component,membrane;GO:0005539,molecular_function,glycosaminoglycan binding;GO:0005901,cellular_component,caveola;GO:1905317,biological_process,inferior endocardial cushion morphogenesis;GO:0046872,molecular_function,metal ion binding;GO:0007219,biological_process,Notch signaling pathway;GO:1990086,biological_process,lens fiber cell apoptotic process","-"]
["MTOR",7.857209197,2.054824806,1.933530254,5.932813273,6.03e-13,1.15e-11,"GO:0031641,biological_process,regulation of myelination;GO:0016605,cellular_component,PML body;GO:0003007,biological_process,heart morphogenesis;GO:0055006,biological_process,cardiac cell development;GO:0051896,biological_process,regulation of protein kinase B signaling;GO:0001932,biological_process,regulation of protein phosphorylation;GO:0010592,biological_process,positive regulation of lamellipodium assembly;GO:0006207,biological_process,'de novo' pyrimidine nucleobase biosynthetic process;GO:0038202,biological_process,TORC1 signaling;GO:0051549,biological_process,positive regulation of keratinocyte migration;GO:0032868,biological_process,response to insulin;GO:0035264,biological_process,multicellular organism growth;GO:0048714,biological_process,positive regulation of oligodendrocyte differentiation;GO:0031529,biological_process,ruffle organization;GO:0009267,biological_process,cellular response to starvation;GO:0030030,biological_process,cell projection organization;GO:0004672,molecular_function,protein kinase activity;GO:0018107,biological_process,peptidyl-threonine phosphorylation;GO:0001156,molecular_function,TFIIIC-class transcription factor binding;GO:0071233,biological_process,cellular response to leucine;GO:0003179,biological_process,heart valve morphogenesis;GO:0043200,biological_process,response to amino acid;GO:0010507,biological_process,negative regulation of autophagy;GO:0007281,biological_process,germ cell development;GO:0008361,biological_process,regulation of cell size;GO:0018105,biological_process,peptidyl-serine phosphorylation;GO:0016301,molecular_function,kinase activity;GO:0045670,biological_process,regulation of osteoclast differentiation;GO:0001558,biological_process,regulation of cell growth;GO:0016020,cellular_component,membrane;GO:0005737,cellular_component,cytoplasm;GO:0045945,biological_process,positive regulation of transcription by RNA polymerase III;GO:0001030,molecular_function,RNA polymerase III type 1 promoter DNA binding;GO:0055013,biological_process,cardiac muscle cell development;GO:0044877,molecular_function,protein-containing complex binding;GO:0043022,molecular_function,ribosome binding;GO:0016310,biological_process,phosphorylation;GO:0005524,molecular_function,ATP binding;GO:0043087,biological_process,regulation of GTPase activity;GO:0046889,biological_process,positive regulation of lipid biosynthetic process;GO:0005829,cellular_component,cytosol;GO:0006112,biological_process,energy reserve metabolic process;GO:0042802,molecular_function,identical protein binding;GO:1903691,biological_process,positive regulation of wound healing, spreading of epidermal cells;GO:0031929,biological_process,TOR signaling;GO:0010718,biological_process,positive regulation of epithelial to mesenchymal transition;GO:0010628,biological_process,positive regulation of gene expression;GO:0009791,biological_process,post-embryonic development;GO:0030425,cellular_component,dendrite;GO:0032956,biological_process,regulation of actin cytoskeleton organization;GO:0001032,molecular_function,RNA polymerase III type 3 promoter DNA binding;GO:0007584,biological_process,response to nutrient;GO:0090559,biological_process,regulation of membrane permeability;GO:0005634,cellular_component,nucleus;GO:0016740,molecular_function,transferase activity;GO:0045792,biological_process,negative regulation of cell size;GO:0031932,cellular_component,TORC2 complex;GO:0010831,biological_process,positive regulation of myotube differentiation;GO:0060048,biological_process,cardiac muscle contraction;GO:0071456,biological_process,cellular response to hypoxia;GO:0051219,molecular_function,phosphoprotein binding;GO:0031931,cellular_component,TORC1 complex;GO:0031669,biological_process,cellular response to nutrient levels;GO:0006468,biological_process,protein phosphorylation;GO:0000166,molecular_function,nucleotide binding;GO:0045859,biological_process,regulation of protein kinase activity;GO:0012505,cellular_component,endomembrane system;GO:0050882,biological_process,voluntary musculoskeletal movement;GO:0030838,biological_process,positive regulation of actin filament polymerization;GO:0051496,biological_process,positive regulation of stress fiber assembly;GO:0016242,biological_process,negative regulation of macroautophagy;GO:0001031,molecular_function,RNA polymerase III type 2 promoter DNA binding;GO:0048738,biological_process,cardiac muscle tissue development;GO:0005764,cellular_component,lysosome;GO:0046777,biological_process,protein autophosphorylation;GO:0071230,biological_process,cellular response to amino acid stimulus;GO:0050731,biological_process,positive regulation of peptidyl-tyrosine phosphorylation;GO:0004674,molecular_function,protein serine/threonine kinase activity;GO:1901838,biological_process,positive regulation of transcription of nucleolar large rRNA by RNA polymerase I;GO:0051534,-,-;GO:0034198,biological_process,cellular response to amino acid starvation;GO:1990253,biological_process,cellular response to leucine starvation;GO:0045727,biological_process,positive regulation of translation;GO:0001934,biological_process,positive regulation of protein phosphorylation","K07203,ko01522,Endocrine resistance;K07203,ko04139,Regulation of mitophagy - yeast;K07203,ko05215,Prostate cancer;K07203,ko04072,Phospholipase D signaling pathway;K07203,ko04151,PI3K-Akt signaling pathway;K07203,ko01521,EGFR tyrosine kinase inhibitor resistance;K07203,ko05230,Central carbon metabolism in cancer;K07203,ko04920,Adipocytokine signaling pathway;K07203,ko04919,Thyroid hormone signaling pathway;K07203,ko04012,ErbB signaling pathway;K07203,ko05214,Glioma;K07203,ko04212,Longevity regulating pathway - worm;K07203,ko04213,Longevity regulating pathway - multiple species;K07203,ko04152,AMPK signaling pathway;K07203,ko04910,Insulin signaling pathway;K07203,ko04150,mTOR signaling pathway;K07203,ko05206,MicroRNAs in cancer;K07203,ko05221,Acute myeloid leukemia;K07203,ko04930,Type II diabetes mellitus;K07203,ko04630,Jak-STAT signaling pathway;K07203,ko05231,Choline metabolism in cancer;K07203,ko04066,HIF-1 signaling pathway;K07203,ko05205,Proteoglycans in cancer;K07203,ko04211,Longevity regulating pathway;K07203,ko04931,Insulin resistance;K07203,ko05200,Pathways in cancer"]
["THBS1",24.73651219,6.726438925,1.878140554,7.181031284,{"v":1.9e-15,"d":"1.90E-15"},{"v":6.43e-14,"d":"6.43E-14"},"GO:0016525,biological_process,negative regulation of angiogenesis;GO:0007155,biological_process,cell adhesion;GO:0031012,cellular_component,extracellular matrix;GO:0050840,molecular_function,extracellular matrix binding;GO:0005509,molecular_function,calcium ion binding;GO:0030198,biological_process,extracellular matrix organization;GO:0006954,biological_process,inflammatory response;GO:0008201,molecular_function,heparin binding;GO:0005576,cellular_component,extracellular region;GO:0005615,cellular_component,extracellular space","K16857,ko04115,p53 signaling pathway;K16857,ko04015,Rap1 signaling pathway;K16857,ko05219,Bladder cancer;K16857,ko04510,Focal adhesion;K16857,ko05206,MicroRNAs in cancer;K16857,ko04512,ECM-receptor interaction;K16857,ko05205,Proteoglycans in cancer;K16857,ko04151,PI3K-Akt signaling pathway;K16857,ko05144,Malaria;K16857,ko04145,Phagosome;K16857,ko04350,TGF-beta signaling pathway"]
["SRC",8.774424045,2.583617146,1.761818298,5.236461473,{"v":2.06e-09,"d":"2.06E-09"},{"v":1.77E-8,"d":"1.77E-08"},"GO:0038083,biological_process,peptidyl-tyrosine autophosphorylation;GO:0004672,molecular_function,protein kinase activity;GO:0071801,biological_process,regulation of podosome assembly;GO:0007417,biological_process,central nervous system development;GO:0005524,molecular_function,ATP binding;GO:0050847,biological_process,progesterone receptor signaling pathway;GO:0016301,molecular_function,kinase activity;GO:0007155,biological_process,cell adhesion;GO:0036035,biological_process,osteoclast development;GO:0048008,biological_process,platelet-derived growth factor receptor signaling pathway;GO:0016310,biological_process,phosphorylation;GO:0045453,biological_process,bone resorption;GO:0070851,molecular_function,growth factor receptor binding;GO:0007173,biological_process,epidermal growth factor receptor signaling pathway;GO:2001243,biological_process,negative regulation of intrinsic apoptotic signaling pathway;GO:0042127,biological_process,regulation of cell proliferation;GO:0016740,molecular_function,transferase activity;GO:0004715,molecular_function,non-membrane spanning protein tyrosine kinase activity;GO:0004713,molecular_function,protein tyrosine kinase activity;GO:0051427,molecular_function,hormone receptor binding;GO:0006468,biological_process,protein phosphorylation;GO:0000166,molecular_function,nucleotide binding;GO:0045087,biological_process,innate immune response;GO:0030520,biological_process,intracellular estrogen receptor signaling pathway;GO:2001237,biological_process,negative regulation of extrinsic apoptotic signaling pathway;GO:0051726,biological_process,regulation of cell cycle;GO:0031234,cellular_component,extrinsic component of cytoplasmic side of plasma membrane;GO:0016477,biological_process,cell migration","-"]
["TGFB1",31.46090251,9.512156837,1.724591675,6.073076164,{"v":3.28e-11,"d":"3.28E-11"},4.18E-10,"GO:0010469,biological_process,regulation of signaling receptor activity;GO:0003179,biological_process,heart valve morphogenesis;GO:0060389,biological_process,pathway-restricted SMAD protein phosphorylation;GO:0045216,biological_process,cell-cell junction organization;GO:0032967,biological_process,positive regulation of collagen biosynthetic process;GO:0033138,biological_process,positive regulation of peptidyl-serine phosphorylation;GO:0005114,molecular_function,type II transforming growth factor beta receptor binding;GO:0045599,biological_process,negative regulation of fat cell differentiation;GO:0007435,biological_process,salivary gland morphogenesis;GO:0017015,biological_process,regulation of transforming growth factor beta receptor signaling pathway;GO:1900126,biological_process,negative regulation of hyaluronan biosynthetic process;GO:0005634,cellular_component,nucleus;GO:0005576,cellular_component,extracellular region;GO:0032930,biological_process,positive regulation of superoxide anion generation;GO:0002028,biological_process,regulation of sodium ion transport;GO:0001657,biological_process,ureteric bud development;GO:0048642,biological_process,negative regulation of skeletal muscle tissue development;GO:0010629,biological_process,negative regulation of gene expression;GO:0006754,biological_process,ATP biosynthetic process;GO:0002244,biological_process,hematopoietic progenitor cell differentiation;GO:0060390,biological_process,regulation of SMAD protein signal transduction;GO:0019049,biological_process,evasion or tolerance of host defenses by virus;GO:0072562,cellular_component,blood microparticle;GO:0030335,biological_process,positive regulation of cell migration;GO:0031334,biological_process,positive regulation of protein complex assembly;GO:0002513,biological_process,tolerance induction to self antigen;GO:0070374,biological_process,positive regulation of ERK1 and ERK2 cascade;GO:0050714,biological_process,positive regulation of protein secretion;GO:0007173,biological_process,epidermal growth factor receptor signaling pathway;GO:0045892,biological_process,negative regulation of transcription, DNA-templated;GO:0051098,biological_process,regulation of binding;GO:0005902,cellular_component,microvillus;GO:1903799,biological_process,negative regulation of production of miRNAs involved in gene silencing by miRNA;GO:0060391,biological_process,positive regulation of SMAD protein signal transduction;GO:0043552,biological_process,positive regulation of phosphatidylinositol 3-kinase activity;GO:0043539,molecular_function,protein serine/threonine kinase activator activity;GO:0070306,biological_process,lens fiber cell differentiation;GO:0034713,molecular_function,type I transforming growth factor beta receptor binding;GO:0071560,biological_process,cellular response to transforming growth factor beta stimulus;GO:0048535,biological_process,lymph node development;GO:0019899,molecular_function,enzyme binding;GO:0007050,biological_process,cell cycle arrest;GO:0050868,biological_process,negative regulation of T cell activation;GO:0042110,biological_process,T cell activation;GO:0043536,biological_process,positive regulation of blood vessel endothelial cell migration;GO:0009611,biological_process,response to wounding;GO:0007183,biological_process,SMAD protein complex assembly;GO:0042130,biological_process,negative regulation of T cell proliferation;GO:0000122,biological_process,negative regulation of transcription by RNA polymerase II;GO:0007179,biological_process,transforming growth factor beta receptor signaling pathway;GO:1902895,biological_process,positive regulation of pri-miRNA transcription by RNA polymerase II;GO:0060325,biological_process,face morphogenesis;GO:1903077,biological_process,negative regulation of protein localization to plasma membrane;GO:0043537,biological_process,negative regulation of blood vessel endothelial cell migration;GO:0001837,biological_process,epithelial to mesenchymal transition;GO:0007182,biological_process,common-partner SMAD protein phosphorylation;GO:0005615,cellular_component,extracellular space;GO:0032700,biological_process,negative regulation of interleukin-17 production;GO:0045786,biological_process,negative regulation of cell cycle;GO:0045589,biological_process,regulation of regulatory T cell differentiation;GO:0043406,biological_process,positive regulation of MAP kinase activity;GO:0071158,biological_process,positive regulation of cell cycle arrest;GO:0030879,biological_process,mammary gland development;GO:0001843,biological_process,neural tube closure;GO:1900182,biological_process,positive regulation of protein localization to nucleus;GO:0016202,biological_process,regulation of striated muscle tissue development;GO:0035066,biological_process,positive regulation of histone acetylation;GO:0010628,biological_process,positive regulation of gene expression;GO:0006874,biological_process,cellular calcium ion homeostasis;GO:0034714,molecular_function,type III transforming growth factor beta receptor binding;GO:0030214,biological_process,hyaluronan catabolic process;GO:0042307,biological_process,positive regulation of protein import into nucleus;GO:0008284,biological_process,positive regulation of cell proliferation;GO:2000679,biological_process,positive regulation of transcription regulatory region DNA binding;GO:0010468,biological_process,regulation of gene expression;GO:0021915,biological_process,neural tube development;GO:0005515,molecular_function,protein binding;GO:0048298,biological_process,positive regulation of isotype switching to IgA isotypes;GO:2000249,biological_process,regulation of actin cytoskeleton reorganization;GO:0001933,biological_process,negative regulation of protein phosphorylation;GO:0045591,biological_process,positive regulation of regulatory T cell differentiation;GO:0097191,biological_process,extrinsic apoptotic signaling pathway;GO:0042482,biological_process,positive regulation of odontogenesis;GO:0032740,biological_process,positive regulation of interleukin-17 production;GO:0022408,biological_process,negative regulation of cell-cell adhesion;GO:0008083,molecular_function,growth factor activity;GO:0045930,biological_process,negative regulation of mitotic cell cycle;GO:0005578,,;GO:0001775,biological_process,cell activation;GO:0007492,biological_process,endoderm development;GO:0031293,biological_process,membrane protein intracellular domain proteolysis;GO:0032667,biological_process,regulation of interleukin-23 production;GO:0008354,biological_process,germ cell migration;GO:0009986,cellular_component,cell surface;GO:0031663,biological_process,lipopolysaccharide-mediated signaling pathway;GO:0048146,biological_process,positive regulation of fibroblast proliferation;GO:1990402,biological_process,embryonic liver development;GO:0006796,biological_process,phosphate-containing compound metabolic process;GO:0060751,biological_process,branch elongation involved in mammary gland duct branching;GO:0006954,biological_process,inflammatory response;GO:1903911,biological_process,positive regulation of receptor clustering;GO:0032270,biological_process,positive regulation of cellular protein metabolic process;GO:0010862,biological_process,positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0043011,biological_process,myeloid dendritic cell differentiation;GO:0042127,biological_process,regulation of cell proliferation;GO:0045662,biological_process,negative regulation of myoblast differentiation;GO:0061035,biological_process,regulation of cartilage development;GO:0000165,biological_process,MAPK cascade;GO:0045944,biological_process,positive regulation of transcription by RNA polymerase II;GO:0030501,biological_process,positive regulation of bone mineralization;GO:0071407,biological_process,cellular response to organic cyclic compound;GO:0070723,biological_process,response to cholesterol;GO:0002062,biological_process,chondrocyte differentiation;GO:0006468,biological_process,protein phosphorylation;GO:0030279,biological_process,negative regulation of ossification;GO:0060762,biological_process,regulation of branching involved in mammary gland duct morphogenesis;GO:0000060,biological_process,protein import into nucleus, translocation;GO:0032355,biological_process,response to estradiol;GO:0042306,biological_process,regulation of protein import into nucleus;GO:2000727,biological_process,positive regulation of cardiac muscle cell differentiation;GO:0010800,biological_process,positive regulation of peptidyl-threonine phosphorylation;GO:0045596,biological_process,negative regulation of cell differentiation;GO:0001934,biological_process,positive regulation of protein phosphorylation;GO:0085029,biological_process,extracellular matrix assembly;GO:0045066,biological_process,regulatory T cell differentiation;GO:0001570,biological_process,vasculogenesis;GO:0050731,biological_process,positive regulation of peptidyl-tyrosine phosphorylation;GO:0010936,biological_process,negative regulation of macrophage cytokine production;GO:0006611,biological_process,protein export from nucleus;GO:0055010,biological_process,ventricular cardiac muscle tissue morphogenesis;GO:0060744,biological_process,mammary gland branching involved in thelarche;GO:1901666,biological_process,positive regulation of NAD+ ADP-ribosyltransferase activity;GO:0060965,biological_process,negative regulation of gene silencing by miRNA;GO:0031065,biological_process,positive regulation of histone deacetylation;GO:0008156,biological_process,negative regulation of DNA replication;GO:0051897,biological_process,positive regulation of protein kinase B signaling;GO:0007507,biological_process,heart development;GO:0043117,biological_process,positive regulation of vascular permeability;GO:1903800,biological_process,positive regulation of production of miRNAs involved in gene silencing by miRNA;GO:0005737,cellular_component,cytoplasm;GO:0050921,biological_process,positive regulation of chemotaxis;GO:0051101,biological_process,regulation of DNA binding;GO:0045893,biological_process,positive regulation of transcription, DNA-templated;GO:0043932,biological_process,ossification involved in bone remodeling;GO:0043029,biological_process,T cell homeostasis;GO:0007093,biological_process,mitotic cell cycle checkpoint;GO:0042802,molecular_function,identical protein binding;GO:0002460,biological_process,adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;GO:0030217,biological_process,T cell differentiation;GO:0010718,biological_process,positive regulation of epithelial to mesenchymal transition;GO:0003823,molecular_function,antigen binding;GO:0032943,biological_process,mononuclear cell proliferation;GO:0043491,biological_process,protein kinase B signaling;GO:0010763,biological_process,positive regulation of fibroblast migration;GO:0035307,biological_process,positive regulation of protein dephosphorylation;GO:0050680,biological_process,negative regulation of epithelial cell proliferation;GO:0032801,biological_process,receptor catabolic process;GO:0032570,biological_process,response to progesterone;GO:0030308,biological_process,negative regulation of cell growth;GO:0008283,biological_process,cell proliferation;GO:0008285,biological_process,negative regulation of cell proliferation;GO:0071363,biological_process,cellular response to growth factor stimulus;GO:0014003,biological_process,oligodendrocyte development;GO:0005160,molecular_function,transforming growth factor beta receptor binding;GO:0007219,biological_process,Notch signaling pathway;GO:1905313,biological_process,transforming growth factor beta receptor signaling pathway involved in heart development;GO:0016477,biological_process,cell migration","K13375,ko05140,Leishmaniasis;K13375,ko04672,Intestinal immune network for IgA production;K13375,ko05161,Hepatitis B;K13375,ko05145,Toxoplasmosis;K13375,ko05321,Inflammatory bowel disease (IBD);K13375,ko04350,TGF-beta signaling pathway;K13375,ko05144,Malaria;K13375,ko05152,Tuberculosis;K13375,ko04068,FoxO signaling pathway;K13375,ko05146,Amoebiasis;K13375,ko04932,Non-alcoholic fatty liver disease (NAFLD);K13375,ko05323,Rheumatoid arthritis;K13375,ko05212,Pancreatic cancer;K13375,ko05414,Dilated cardiomyopathy;K13375,ko05200,Pathways in cancer;K13375,ko05410,Hypertrophic cardiomyopathy (HCM);K13375,ko04144,Endocytosis;K13375,ko05210,Colorectal cancer;K13375,ko05142,Chagas disease (American trypanosomiasis);K13375,ko04390,Hippo signaling pathway;K13375,ko04060,Cytokine-cytokine receptor interaction;K13375,ko04380,Osteoclast differentiation;K13375,ko04010,MAPK signaling pathway;K13375,ko05220,Chronic myeloid leukemia;K13375,ko04110,Cell cycle;K13375,ko05211,Renal cell carcinoma;K13375,ko05205,Proteoglycans in cancer;K13375,ko05166,HTLV-I infection;K13375,ko04933,AGE-RAGE signaling pathway in diabetic complications"]
["AKT3",6.816797838,2.10949553,1.69048247,5.434639943,{"v":2.58e-09,"d":"2.58E-09"},{"v":2.16e-08,"d":"2.16E-08"},"GO:0004672,molecular_function,protein kinase activity;GO:0016301,molecular_function,kinase activity;GO:0090050,biological_process,positive regulation of cell migration involved in sprouting angiogenesis;GO:0048873,biological_process,homeostasis of number of cells within a tissue;GO:2000773,biological_process,negative regulation of cellular senescence;GO:0045766,biological_process,positive regulation of angiogenesis;GO:1905564,biological_process,positive regulation of vascular endothelial cell proliferation;GO:0045793,biological_process,positive regulation of cell size;GO:0032008,biological_process,positive regulation of TOR signaling;GO:0000002,biological_process,mitochondrial genome maintenance;GO:0016740,molecular_function,transferase activity;GO:1905653,biological_process,positive regulation of artery morphogenesis;GO:0048854,biological_process,brain morphogenesis;GO:0043536,biological_process,positive regulation of blood vessel endothelial cell migration;GO:0004674,molecular_function,protein serine/threonine kinase activity;GO:0005524,molecular_function,ATP binding;GO:0006468,biological_process,protein phosphorylation;GO:0000166,molecular_function,nucleotide binding;GO:0016310,biological_process,phosphorylation;GO:0007165,biological_process,signal transduction;GO:0001938,biological_process,positive regulation of endothelial cell proliferation","-"]
["BMP4",3.698276111,1.169467195,1.651639594,3.053771401,0.00108952,0.002610728,"GO:0021983,biological_process,pituitary gland development;GO:0000122,biological_process,negative regulation of transcription by RNA polymerase II;GO:0010159,biological_process,specification of animal organ position;GO:0048646,biological_process,anatomical structure formation involved in morphogenesis;GO:0051145,biological_process,smooth muscle cell differentiation;GO:0030900,biological_process,forebrain development;GO:0005576,cellular_component,extracellular region;GO:0061626,biological_process,pharyngeal arch artery morphogenesis;GO:0072001,biological_process,renal system development;GO:0060449,biological_process,bud elongation involved in lung branching;GO:0060976,biological_process,coronary vasculature development;GO:0001759,biological_process,organ induction;GO:0001501,biological_process,skeletal system development;GO:0010469,biological_process,regulation of signaling receptor activity;GO:0001657,biological_process,ureteric bud development;GO:0060235,biological_process,lens induction in camera-type eye;GO:0048704,biological_process,embryonic skeletal system morphogenesis;GO:0042475,biological_process,odontogenesis of dentin-containing tooth;GO:0001938,biological_process,positive regulation of endothelial cell proliferation;GO:0002244,biological_process,hematopoietic progenitor cell differentiation;GO:0001822,biological_process,kidney development;GO:0055007,biological_process,cardiac muscle cell differentiation;GO:0030335,biological_process,positive regulation of cell migration;GO:0048706,biological_process,embryonic skeletal system development;GO:0070374,biological_process,positive regulation of ERK1 and ERK2 cascade;GO:0072198,biological_process,mesenchymal cell proliferation involved in ureter development;GO:0060592,biological_process,mammary gland formation;GO:0060272,biological_process,embryonic skeletal joint morphogenesis;GO:0090191,biological_process,negative regulation of branching involved in ureteric bud morphogenesis;GO:0060348,biological_process,bone development;GO:0060440,biological_process,trachea formation;GO:0061151,biological_process,BMP signaling pathway involved in renal system segmentation;GO:0072161,biological_process,mesenchymal cell differentiation involved in kidney development;GO:0045603,biological_process,positive regulation of endothelial cell differentiation;GO:0060684,biological_process,epithelial-mesenchymal cell signaling;GO:0060687,biological_process,regulation of branching involved in prostate gland morphogenesis;GO:1902895,biological_process,positive regulation of pri-miRNA transcription by RNA polymerase II;GO:0051150,biological_process,regulation of smooth muscle cell differentiation;GO:0072205,biological_process,metanephric collecting duct development;GO:0035993,biological_process,deltoid tuberosity development;GO:0003014,biological_process,renal system process;GO:0005615,cellular_component,extracellular space;GO:0060686,biological_process,negative regulation of prostatic bud formation;GO:0021904,biological_process,dorsal/ventral neural tube patterning;GO:0010629,biological_process,negative regulation of gene expression;GO:0003148,biological_process,outflow tract septum morphogenesis;GO:0001843,biological_process,neural tube closure;GO:0001958,biological_process,endochondral ossification;GO:0060113,biological_process,inner ear receptor cell differentiation;GO:0048660,biological_process,regulation of smooth muscle cell proliferation;GO:0010628,biological_process,positive regulation of gene expression;GO:0060395,biological_process,SMAD protein signal transduction;GO:0045165,biological_process,cell fate commitment;GO:0021978,biological_process,telencephalon regionalization;GO:0060429,biological_process,epithelium development;GO:0007500,biological_process,mesodermal cell fate determination;GO:0072193,biological_process,ureter smooth muscle cell differentiation;GO:0030326,biological_process,embryonic limb morphogenesis;GO:0008284,biological_process,positive regulation of cell proliferation;GO:0042733,biological_process,embryonic digit morphogenesis;GO:0061149,biological_process,BMP signaling pathway involved in ureter morphogenesis;GO:0060363,biological_process,cranial suture morphogenesis;GO:0001944,biological_process,vasculature development;GO:0001525,biological_process,angiogenesis;GO:0003149,biological_process,membranous septum morphogenesis;GO:2001237,biological_process,negative regulation of extrinsic apoptotic signaling pathway;GO:0001934,biological_process,positive regulation of protein phosphorylation;GO:0035990,biological_process,tendon cell differentiation;GO:0008083,molecular_function,growth factor activity;GO:0009948,biological_process,anterior/posterior axis specification;GO:0003197,biological_process,endocardial cushion development;GO:0010468,biological_process,regulation of gene expression;GO:0048333,biological_process,mesodermal cell differentiation;GO:0001649,biological_process,osteoblast differentiation;GO:0007281,biological_process,germ cell development;GO:0032331,biological_process,negative regulation of chondrocyte differentiation;GO:0060197,biological_process,cloacal septation;GO:0060442,biological_process,branching involved in prostate gland morphogenesis;GO:0001707,biological_process,mesoderm formation;GO:0003184,biological_process,pulmonary valve morphogenesis;GO:0045778,biological_process,positive regulation of ossification;GO:0048598,biological_process,embryonic morphogenesis;GO:0001656,biological_process,metanephros development;GO:0030509,biological_process,BMP signaling pathway;GO:0061035,biological_process,regulation of cartilage development;GO:0045944,biological_process,positive regulation of transcription by RNA polymerase II;GO:0002062,biological_process,chondrocyte differentiation;GO:0030324,biological_process,lung development;GO:0042487,biological_process,regulation of odontogenesis of dentin-containing tooth;GO:0003151,biological_process,outflow tract morphogenesis;GO:1901964,biological_process,positive regulation of cell proliferation involved in outflow tract morphogenesis;GO:0009888,biological_process,tissue development;GO:0048701,biological_process,embryonic cranial skeleton morphogenesis;GO:0035116,biological_process,embryonic hindlimb morphogenesis;GO:0072138,biological_process,mesenchymal cell proliferation involved in ureteric bud development;GO:0050680,biological_process,negative regulation of epithelial cell proliferation;GO:1905312,biological_process,positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis;GO:0048593,biological_process,camera-type eye morphogenesis;GO:0030218,biological_process,erythrocyte differentiation;GO:0060512,biological_process,prostate gland morphogenesis;GO:0007507,biological_process,heart development;GO:0043066,biological_process,negative regulation of apoptotic process;GO:0045666,biological_process,positive regulation of neuron differentiation;GO:0008201,molecular_function,heparin binding;GO:0072104,biological_process,glomerular capillary formation;GO:0001658,biological_process,branching involved in ureteric bud morphogenesis;GO:0045597,biological_process,positive regulation of cell differentiation;GO:0010718,biological_process,positive regulation of epithelial to mesenchymal transition;GO:0072192,biological_process,ureter epithelial cell differentiation;GO:0045595,biological_process,regulation of cell differentiation;GO:0048745,biological_process,smooth muscle tissue development;GO:0003180,biological_process,aortic valve morphogenesis;GO:2001012,biological_process,mesenchymal cell differentiation involved in renal system development;GO:0007492,biological_process,endoderm development;GO:0009791,biological_process,post-embryonic development;GO:0061047,biological_process,positive regulation of branching involved in lung morphogenesis;GO:0061312,biological_process,BMP signaling pathway involved in heart development;GO:0043010,biological_process,camera-type eye development;GO:0008285,biological_process,negative regulation of cell proliferation;GO:0071363,biological_process,cellular response to growth factor stimulus;GO:0048663,biological_process,neuron fate commitment;GO:0060688,biological_process,regulation of morphogenesis of a branching structure;GO:0001568,biological_process,blood vessel development;GO:0072015,biological_process,glomerular visceral epithelial cell development;GO:0030513,biological_process,positive regulation of BMP signaling pathway","K04662,ko04060,Cytokine-cytokine receptor interaction;K04662,ko04350,TGF-beta signaling pathway;K04662,ko04341,Hedgehog signaling pathway - fly;K04662,ko04013,MAPK signaling pathway - fly;K04662,ko05217,Basal cell carcinoma;K04662,ko05200,Pathways in cancer;K04662,ko04390,Hippo signaling pathway;K04662,ko04550,Signaling pathways regulating pluripotency of stem cells"]
["CAV2",22.59402768,7.190996773,1.650998394,6.702303113,{"v":1.14e-11,"d":"1.14E-11"},{"v":1.61e-10,"d":"1.61E-10"},"GO:0006906,biological_process,vesicle fusion;GO:0070836,biological_process,caveola assembly;GO:0019901,molecular_function,protein kinase binding;GO:0001937,biological_process,negative regulation of endothelial cell proliferation;GO:0032991,cellular_component,protein-containing complex;GO:0007005,biological_process,mitochondrion organization;GO:0043547,biological_process,positive regulation of GTPase activity;GO:0005886,cellular_component,plasma membrane;GO:0046982,molecular_function,protein heterodimerization activity;GO:0097110,molecular_function,scaffold protein binding;GO:0048741,biological_process,skeletal muscle fiber development;GO:0005925,cellular_component,focal adhesion;GO:0032947,molecular_function,protein-containing complex scaffold activity;GO:0002080,cellular_component,acrosomal membrane;GO:0005794,cellular_component,Golgi apparatus;GO:0042803,molecular_function,protein homodimerization activity;GO:0001938,biological_process,positive regulation of endothelial cell proliferation;GO:0007029,biological_process,endoplasmic reticulum organization;GO:0030512,biological_process,negative regulation of transforming growth factor beta receptor signaling pathway;GO:0005887,cellular_component,integral component of plasma membrane;GO:0016021,cellular_component,integral component of membrane;GO:0060161,biological_process,positive regulation of dopamine receptor signaling pathway;GO:0016050,biological_process,vesicle organization;GO:0008286,biological_process,insulin receptor signaling pathway;GO:0051259,biological_process,protein complex oligomerization;GO:0000139,cellular_component,Golgi membrane;GO:0007088,biological_process,regulation of mitotic nuclear division;GO:0016020,cellular_component,membrane;GO:0031410,cellular_component,cytoplasmic vesicle;GO:0045121,cellular_component,membrane raft;GO:0044791,biological_process,positive regulation by host of viral release from host cell;GO:0005901,cellular_component,caveola;GO:0019065,biological_process,receptor-mediated endocytosis of virus by host cell;GO:0048278,biological_process,vesicle docking;GO:0008285,biological_process,negative regulation of cell proliferation;GO:0048471,cellular_component,perinuclear region of cytoplasm;GO:0030133,cellular_component,transport vesicle;GO:0043410,biological_process,positive regulation of MAPK cascade;GO:0005622,cellular_component,intracellular;GO:0031234,cellular_component,extrinsic component of cytoplasmic side of plasma membrane;GO:0030674,molecular_function,protein binding, bridging;GO:0044794,biological_process,positive regulation by host of viral process","K12958,ko04510,Focal adhesion;K12958,ko04144,Endocytosis;K12958,ko05205,Proteoglycans in cancer;K12958,ko05100,Bacterial invasion of epithelial cells"]
["NRP2",2.40946175,0.778129943,1.627525075,4.526961377,{"v":1.49e-06,"d":"1.49E-06"},{"v":6.8e-06,"d":"6.80E-06"},"GO:0001755,biological_process,neural crest cell migration;GO:0097490,biological_process,sympathetic neuron projection extension;GO:0061551,biological_process,trigeminal ganglion development;GO:0005021,molecular_function,vascular endothelial growth factor-activated receptor activity;GO:0021828,biological_process,gonadotrophin-releasing hormone neuronal migration to the hypothalamus;GO:0007507,biological_process,heart development;GO:0007411,biological_process,axon guidance;GO:1904835,biological_process,dorsal root ganglion morphogenesis;GO:0021612,biological_process,facial nerve structural organization;GO:0021649,biological_process,vestibulocochlear nerve structural organization;GO:0097374,biological_process,sensory neuron axon guidance;GO:0048846,biological_process,axon extension involved in axon guidance;GO:0003148,biological_process,outflow tract septum morphogenesis;GO:0021675,biological_process,nerve development;GO:0016021,cellular_component,integral component of membrane;GO:0030424,cellular_component,axon;GO:0050919,biological_process,negative chemotaxis;GO:0017154,molecular_function,semaphorin receptor activity;GO:0038084,biological_process,vascular endothelial growth factor signaling pathway;GO:0001525,biological_process,angiogenesis;GO:0016020,cellular_component,membrane;GO:0001764,biological_process,neuron migration;GO:1903375,biological_process,facioacoustic ganglion development;GO:1902285,biological_process,semaphorin-plexin signaling pathway involved in neuron projection guidance;GO:1901166,biological_process,neural crest cell migration involved in autonomic nervous system development;GO:0036486,biological_process,ventral trunk neural crest cell migration;GO:0046872,molecular_function,metal ion binding;GO:0061549,biological_process,sympathetic ganglion development;GO:0097491,biological_process,sympathetic neuron projection guidance;GO:1990830,biological_process,cellular response to leukemia inhibitory factor","-"]
["NRP1",0.618278455,0.227504562,1.430494488,2.486380441,0.019530136,0.034357071,"GO:0060982,biological_process,coronary artery morphogenesis;GO:0005886,cellular_component,plasma membrane;GO:0005769,cellular_component,early endosome;GO:0042327,biological_process,positive regulation of phosphorylation;GO:0060385,biological_process,axonogenesis involved in innervation;GO:0021828,biological_process,gonadotrophin-releasing hormone neuronal migration to the hypothalamus;GO:0060978,biological_process,angiogenesis involved in coronary vascular morphogenesis;GO:0045766,biological_process,positive regulation of angiogenesis;GO:0050918,biological_process,positive chemotaxis;GO:0048846,biological_process,axon extension involved in axon guidance;GO:0007229,biological_process,integrin-mediated signaling pathway;GO:0070374,biological_process,positive regulation of ERK1 and ERK2 cascade;GO:0038084,biological_process,vascular endothelial growth factor signaling pathway;GO:1903375,biological_process,facioacoustic ganglion development;GO:0038085,molecular_function,vascular endothelial growth factor binding;GO:1901166,biological_process,neural crest cell migration involved in autonomic nervous system development;GO:0002042,biological_process,cell migration involved in sprouting angiogenesis;GO:0021636,biological_process,trigeminal nerve morphogenesis;GO:0061549,biological_process,sympathetic ganglion development;GO:0031290,biological_process,retinal ganglion cell axon guidance;GO:0007275,biological_process,multicellular organism development;GO:0090050,biological_process,positive regulation of cell migration involved in sprouting angiogenesis;GO:0030154,biological_process,cell differentiation;GO:0048485,biological_process,sympathetic nervous system development;GO:0009887,biological_process,animal organ morphogenesis;GO:0060666,biological_process,dichotomous subdivision of terminal units involved in salivary gland branching;GO:0097443,cellular_component,sorting endosome;GO:0048843,biological_process,negative regulation of axon extension involved in axon guidance;GO:0097490,biological_process,sympathetic neuron projection extension;GO:0061551,biological_process,trigeminal ganglion development;GO:0003148,biological_process,outflow tract septum morphogenesis;GO:0007507,biological_process,heart development;GO:0007411,biological_process,axon guidance;GO:0001569,biological_process,branching involved in blood vessel morphogenesis;GO:0030424,cellular_component,axon;GO:0007399,biological_process,nervous system development;GO:0090259,biological_process,regulation of retinal ganglion cell axon guidance;GO:0061441,biological_process,renal artery morphogenesis;GO:1902336,biological_process,positive regulation of retinal ganglion cell axon guidance;GO:0008045,biological_process,motor neuron axon guidance;GO:1902285,biological_process,semaphorin-plexin signaling pathway involved in neuron projection guidance;GO:0035924,biological_process,cellular response to vascular endothelial growth factor stimulus;GO:0005925,cellular_component,focal adhesion;GO:0050731,biological_process,positive regulation of peptidyl-tyrosine phosphorylation;GO:2001237,biological_process,negative regulation of extrinsic apoptotic signaling pathway;GO:0097475,biological_process,motor neuron migration;GO:0051491,biological_process,positive regulation of filopodium assembly;GO:0038189,biological_process,neuropilin signaling pathway;GO:0019901,molecular_function,protein kinase binding;GO:0032489,biological_process,regulation of Cdc42 protein signal transduction;GO:0007413,biological_process,axonal fasciculation;GO:0043547,biological_process,positive regulation of GTPase activity;GO:0071679,biological_process,commissural neuron axon guidance;GO:0048012,biological_process,hepatocyte growth factor receptor signaling pathway;GO:0048844,biological_process,artery morphogenesis;GO:0021612,biological_process,facial nerve structural organization;GO:0021649,biological_process,vestibulocochlear nerve structural organization;GO:2000251,biological_process,positive regulation of actin cytoskeleton reorganization;GO:0150018,biological_process,basal dendrite development;GO:1900026,biological_process,positive regulation of substrate adhesion-dependent cell spreading;GO:0001764,biological_process,neuron migration;GO:0016021,cellular_component,integral component of membrane;GO:0021785,biological_process,branchiomotor neuron axon guidance;GO:1905040,biological_process,otic placode development;GO:0150020,biological_process,basal dendrite arborization;GO:0017154,molecular_function,semaphorin receptor activity;GO:0002040,biological_process,sprouting angiogenesis;GO:0034446,biological_process,substrate adhesion-dependent cell spreading;GO:0021637,biological_process,trigeminal nerve structural organization;GO:0051496,biological_process,positive regulation of stress fiber assembly;GO:0036486,biological_process,ventral trunk neural crest cell migration;GO:0048010,biological_process,vascular endothelial growth factor receptor signaling pathway;GO:0097491,biological_process,sympathetic neuron projection guidance;GO:0035767,biological_process,endothelial cell chemotaxis;GO:0038190,biological_process,VEGF-activated neuropilin signaling pathway;GO:0006930,biological_process,substrate-dependent cell migration, cell extension;GO:0061299,biological_process,retina vasculature morphogenesis in camera-type eye;GO:0031532,biological_process,actin cytoskeleton reorganization;GO:0035729,biological_process,cellular response to hepatocyte growth factor stimulus;GO:0010595,biological_process,positive regulation of endothelial cell migration;GO:0005096,molecular_function,GTPase activator activity;GO:0048841,biological_process,regulation of axon extension involved in axon guidance;GO:0043005,cellular_component,neuron projection;GO:0043542,biological_process,endothelial cell migration;GO:0016358,biological_process,dendrite development;GO:1902287,biological_process,semaphorin-plexin signaling pathway involved in axon guidance;GO:0048008,biological_process,platelet-derived growth factor receptor signaling pathway;GO:0030517,biological_process,negative regulation of axon extension;GO:0097374,biological_process,sensory neuron axon guidance;GO:0005829,cellular_component,cytosol;GO:0005021,molecular_function,vascular endothelial growth factor-activated receptor activity;GO:0021675,biological_process,nerve development;GO:0048842,biological_process,positive regulation of axon extension involved in axon guidance;GO:0019838,molecular_function,growth factor binding;GO:0001525,biological_process,angiogenesis;GO:0016020,cellular_component,membrane;GO:0005883,cellular_component,neurofilament;GO:1902946,biological_process,protein localization to early endosome;GO:0048666,biological_process,neuron development;GO:1904835,biological_process,dorsal root ganglion morphogenesis;GO:0071526,biological_process,semaphorin-plexin signaling pathway;GO:0043524,biological_process,negative regulation of neuron apoptotic process;GO:0051894,biological_process,positive regulation of focal adhesion assembly;GO:0046872,molecular_function,metal ion binding;GO:1902378,biological_process,VEGF-activated neuropilin signaling pathway involved in axon guidance;GO:1901998,biological_process,toxin transport;GO:0016477,biological_process,cell migration","K06724,ko05166,HTLV-I infection;K06724,ko04360,Axon guidance"]
["CAV1",66.20030508,26.16812423,1.338746294,7.565690352,{"v":2.94e-09,"d":"2.94E-09"},{"v":2.43e-08,"d":"2.43E-08"},"GO:0031397,biological_process,negative regulation of protein ubiquitination;GO:0033138,biological_process,positive regulation of peptidyl-serine phosphorylation;GO:2000286,biological_process,receptor internalization involved in canonical Wnt signaling pathway;GO:0000122,biological_process,negative regulation of transcription by RNA polymerase II;GO:0001960,biological_process,negative regulation of cytokine-mediated signaling pathway;GO:0019901,molecular_function,protein kinase binding;GO:0001666,biological_process,response to hypoxia;GO:0046982,molecular_function,protein heterodimerization activity;GO:0005938,cellular_component,cell cortex;GO:0070320,molecular_function,inward rectifier potassium channel inhibitor activity;GO:0051117,molecular_function,ATPase binding;GO:0006816,biological_process,calcium ion transport;GO:1901380,biological_process,negative regulation of potassium ion transmembrane transport;GO:0009968,biological_process,negative regulation of signal transduction;GO:0045907,biological_process,positive regulation of vasoconstriction;GO:0005768,cellular_component,endosome;GO:0055074,biological_process,calcium ion homeostasis;GO:0098911,biological_process,regulation of ventricular cardiac muscle cell action potential;GO:0002931,biological_process,response to ischemia;GO:0019899,molecular_function,enzyme binding;GO:0051260,biological_process,protein homooligomerization;GO:0042802,molecular_function,identical protein binding;GO:0044325,molecular_function,ion channel binding;GO:0006940,biological_process,regulation of smooth muscle contraction;GO:0048365,molecular_function,Rac GTPase binding;GO:1903609,biological_process,negative regulation of inward rectifier potassium channel activity;GO:0005886,cellular_component,plasma membrane;GO:0001937,biological_process,negative regulation of endothelial cell proliferation;GO:0032991,cellular_component,protein-containing complex;GO:0009617,biological_process,response to bacterium;GO:0005102,molecular_function,signaling receptor binding;GO:0005783,cellular_component,endoplasmic reticulum;GO:0090090,biological_process,negative regulation of canonical Wnt signaling pathway;GO:2000811,biological_process,negative regulation of anoikis;GO:1903598,biological_process,positive regulation of gap junction assembly;GO:0071455,biological_process,cellular response to hyperoxia;GO:0034141,biological_process,positive regulation of toll-like receptor 3 signaling pathway;GO:0000188,biological_process,inactivation of MAPK activity;GO:0051480,biological_process,regulation of cytosolic calcium ion concentration;GO:0030879,biological_process,mammary gland development;GO:0060355,biological_process,positive regulation of cell adhesion molecule production;GO:0010628,biological_process,positive regulation of gene expression;GO:0006874,biological_process,cellular calcium ion homeostasis;GO:0019217,biological_process,regulation of fatty acid metabolic process;GO:0008104,biological_process,protein localization;GO:0005794,cellular_component,Golgi apparatus;GO:0000139,cellular_component,Golgi membrane;GO:2001244,biological_process,positive regulation of intrinsic apoptotic signaling pathway;GO:0042532,biological_process,negative regulation of tyrosine phosphorylation of STAT protein;GO:0097190,biological_process,apoptotic signaling pathway;GO:0031295,biological_process,T cell costimulation;GO:0031410,cellular_component,cytoplasmic vesicle;GO:2000535,biological_process,regulation of entry of bacterium into host cell;GO:0048471,cellular_component,perinuclear region of cytoplasm;GO:0043409,biological_process,negative regulation of MAPK cascade;GO:0032091,biological_process,negative regulation of protein binding;GO:0007519,biological_process,skeletal muscle tissue development;GO:0031398,biological_process,positive regulation of protein ubiquitination;GO:0005622,cellular_component,intracellular;GO:0033484,biological_process,nitric oxide homeostasis;GO:0006641,biological_process,triglyceride metabolic process;GO:0042632,biological_process,cholesterol homeostasis;GO:0070836,biological_process,caveola assembly;GO:0003057,biological_process,regulation of the force of heart contraction by chemical signal;GO:0033137,biological_process,negative regulation of peptidyl-serine phosphorylation;GO:0030857,biological_process,negative regulation of epithelial cell differentiation;GO:0051592,biological_process,response to calcium ion;GO:0010524,biological_process,positive regulation of calcium ion transport into cytosol;GO:0005198,molecular_function,structural molecule activity;GO:0032947,molecular_function,protein-containing complex scaffold activity;GO:0005925,cellular_component,focal adhesion;GO:0010952,biological_process,positive regulation of peptidase activity;GO:0002080,cellular_component,acrosomal membrane;GO:0002026,biological_process,regulation of the force of heart contraction;GO:0034098,cellular_component,VCP-NPL4-UFD1 AAA ATPase complex;GO:0001570,biological_process,vasculogenesis;GO:2001238,biological_process,positive regulation of extrinsic apoptotic signaling pathway;GO:0030193,biological_process,regulation of blood coagulation;GO:0071375,biological_process,cellular response to peptide hormone stimulus;GO:0010608,biological_process,posttranscriptional regulation of gene expression;GO:0051259,biological_process,protein complex oligomerization;GO:0016021,cellular_component,integral component of membrane;GO:0043627,biological_process,response to estrogen;GO:0043085,biological_process,positive regulation of catalytic activity;GO:0045019,biological_process,negative regulation of nitric oxide biosynthetic process;GO:0060546,biological_process,negative regulation of necroptotic process;GO:0016504,molecular_function,peptidase activator activity;GO:0005901,cellular_component,caveola;GO:0032092,biological_process,positive regulation of protein binding;GO:0045121,cellular_component,membrane raft;GO:1900085,biological_process,negative regulation of peptidyl-tyrosine autophosphorylation;GO:0019065,biological_process,receptor-mediated endocytosis of virus by host cell;GO:0052547,biological_process,regulation of peptidase activity;GO:0005929,cellular_component,cilium;GO:1900027,biological_process,regulation of ruffle assembly;GO:0086091,biological_process,regulation of heart rate by cardiac conduction;GO:0043407,biological_process,negative regulation of MAP kinase activity;GO:0030674,molecular_function,protein binding, bridging;GO:0061099,biological_process,negative regulation of protein tyrosine kinase activity;GO:0042310,biological_process,vasoconstriction;GO:0051001,biological_process,negative regulation of nitric-oxide synthase activity;GO:0007595,biological_process,lactation;GO:0072584,biological_process,caveolin-mediated endocytosis;GO:0031623,biological_process,receptor internalization;GO:0071360,biological_process,cellular response to exogenous dsRNA;GO:0048550,biological_process,negative regulation of pinocytosis;GO:1901844,biological_process,regulation of cell communication by electrical coupling involved in cardiac conduction;GO:0030512,biological_process,negative regulation of transforming growth factor beta receptor signaling pathway;GO:0005887,cellular_component,integral component of plasma membrane;GO:0051899,biological_process,membrane depolarization;GO:0086098,biological_process,angiotensin-activated signaling pathway involved in heart process;GO:0001525,biological_process,angiogenesis;GO:0016020,cellular_component,membrane;GO:0060056,biological_process,mammary gland involution;GO:0098903,biological_process,regulation of membrane repolarization during action potential;GO:0019915,biological_process,lipid storage;GO:0032570,biological_process,response to progesterone;GO:0050998,molecular_function,nitric-oxide synthase binding;GO:0008285,biological_process,negative regulation of cell proliferation;GO:0071560,biological_process,cellular response to transforming growth factor beta stimulus;GO:0090263,biological_process,positive regulation of canonical Wnt signaling pathway;GO:0046426,biological_process,negative regulation of JAK-STAT cascade","K06278,ko04510,Focal adhesion;K06278,ko05416,Viral myocarditis;K06278,ko04144,Endocytosis;K06278,ko05205,Proteoglycans in cancer;K06278,ko05100,Bacterial invasion of epithelial cells"]
["TGFB2",1.797892772,0.763339418,1.228688157,2.874263273,0.019707618,0.034616316,"GO:0045778,biological_process,positive regulation of ossification;GO:0008083,molecular_function,growth factor activity;GO:0031012,cellular_component,extracellular matrix;GO:0001942,biological_process,hair follicle development;GO:0060389,biological_process,pathway-restricted SMAD protein phosphorylation;GO:0045216,biological_process,cell-cell junction organization;GO:0007179,biological_process,transforming growth factor beta receptor signaling pathway;GO:0051891,biological_process,positive regulation of cardioblast differentiation;GO:0030199,biological_process,collagen fibril organization;GO:0003007,biological_process,heart morphogenesis;GO:0005114,molecular_function,type II transforming growth factor beta receptor binding;GO:1902895,biological_process,positive regulation of pri-miRNA transcription by RNA polymerase II;GO:0051794,biological_process,regulation of timing of catagen;GO:0007435,biological_process,salivary gland morphogenesis;GO:0048566,biological_process,embryonic digestive tract development;GO:0001666,biological_process,response to hypoxia;GO:0010634,biological_process,positive regulation of epithelial cell migration;GO:0001837,biological_process,epithelial to mesenchymal transition;GO:0005576,cellular_component,extracellular region;GO:0005615,cellular_component,extracellular space;GO:0000902,biological_process,cell morphogenesis;GO:0060317,biological_process,cardiac epithelial to mesenchymal transition;GO:0045726,biological_process,positive regulation of integrin biosynthetic process;GO:0045747,biological_process,positive regulation of Notch signaling pathway;GO:0008219,biological_process,cell death;GO:0010469,biological_process,regulation of signaling receptor activity;GO:0043525,biological_process,positive regulation of neuron apoptotic process;GO:0001654,biological_process,eye development;GO:0010629,biological_process,negative regulation of gene expression;GO:0045823,biological_process,positive regulation of heart contraction;GO:0010002,biological_process,cardioblast differentiation;GO:0034714,molecular_function,type III transforming growth factor beta receptor binding;GO:0042493,biological_process,response to drug;GO:0030307,biological_process,positive regulation of cell growth;GO:0010718,biological_process,positive regulation of epithelial to mesenchymal transition;GO:0060395,biological_process,SMAD protein signal transduction;GO:0014068,biological_process,positive regulation of phosphatidylinositol 3-kinase signaling;GO:0033630,biological_process,positive regulation of cell adhesion mediated by integrin;GO:0050714,biological_process,positive regulation of protein secretion;GO:0032147,biological_process,activation of protein kinase activity;GO:0032909,biological_process,regulation of transforming growth factor beta2 production;GO:0005102,molecular_function,signaling receptor binding;GO:0030308,biological_process,negative regulation of cell growth;GO:0032874,biological_process,positive regulation of stress-activated MAPK cascade;GO:0008284,biological_process,positive regulation of cell proliferation;GO:0010936,biological_process,negative regulation of macrophage cytokine production;GO:0001540,molecular_function,amyloid-beta binding;GO:0050680,biological_process,negative regulation of epithelial cell proliferation;GO:0060038,biological_process,cardiac muscle cell proliferation;GO:0006468,biological_process,protein phosphorylation;GO:0007507,biological_process,heart development;GO:0016525,biological_process,negative regulation of angiogenesis;GO:0010693,biological_process,negative regulation of alkaline phosphatase activity;GO:0032570,biological_process,response to progesterone;GO:0023014,biological_process,signal transduction by protein phosphorylation;GO:0007050,biological_process,cell cycle arrest;GO:0008285,biological_process,negative regulation of cell proliferation;GO:0051795,biological_process,positive regulation of timing of catagen;GO:0009611,biological_process,response to wounding;GO:0005160,molecular_function,transforming growth factor beta receptor binding;GO:0008347,biological_process,glial cell migration;GO:0042803,molecular_function,protein homodimerization activity;GO:0097191,biological_process,extrinsic apoptotic signaling pathway;GO:0016477,biological_process,cell migration","-"]