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["ENSG00000116478.7",1,32757687,32799236,1,"NM_004964","HDAC1",3065,0.264012377,3.653392086,10.89289797,0.001386278,0.076264837,"up"]
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["ENSG00000124575.5",6,26234440,26235216,-1,"NM_005320","HIST1H1D",3007,0.561377064,2.149478433,10.88357804,1.392505E-3,0.076340074,"up"]
["ENSG00000203812.2",1,149822643,149823191,1,"NM_001040874","HIST2H2AA4",723790,0.432255189,3.732391278,10.88339942,0.001392624,0.076340074,"up"]
["ENSG00000176170.9",17,74372665,74383941,1,"NA","SPHK1",8877,0.750076911,1.319941926,10.87872554,1.395758E-3,0.076383916,"up"]
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["ENSG00000253731.1",5,140753651,140892546,1,"NM_018919","PCDHGA6",56109,0.321682204,3.140438475,10.77893604,0.001464434,0.079300075,"up"]
["ENSG00000018408.10",3,149235022,149454501,-1,"NM_001168278","WWTR1",25937,0.394441309,4.022677394,10.77893371,1.464435E-3,0.079300075,"up"]
["ENSG00000135272.5",7,114562209,114659256,1,"NM_001166345","MDFIC",29969,0.286495099,3.136458958,10.77392959,0.00146797,0.079300075,"up"]
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["ENSG00000124785.4",6,5998232,6007200,-1,"NM_016588","NRN1",51299,-0.390210476,6.38227242,10.73485007,0.001495877,0.080498377,"down"]
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["ENSG00000233242.2",9,37112545,37115487,-1,"NA","NA","NA",0.739811845,-2.661674629,6.342834643,0.013558538,0.228743816,"up"]
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["ENSG00000184979.9",22,18632666,18660164,1,"NM_017414","USP18",11274,0.421278881,1.551613948,6.339277051,0.013583918,0.228743816,"up"]
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["ENSG00000090061.13",14,99947506,100001381,1,"NA","CCNK",8812,0.156827852,3.598666532,6.327808641,0.013666074,0.229234203,"up"]
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["ENSG00000161381.9",17,37219556,37310647,-1,"NM_020405","PLXDC1",57125,-0.227226817,4.546850237,6.324711385,0.013688351,0.229271267,"down"]
["ENSG00000179859.7",17,7816642,7819271,-1,"NA","NA",284023,0.172679726,2.133126127,6.324421486,0.013690438,0.229271267,"up"]
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["ENSG00000237475.2","X",72755339,72756077,1,"NA","RPL7P53","NA",0.464463751,-3.004242162,2.038559682,0.156827345,0.535566282,"up"]
["ENSG00000152611.7",5,35904397,35938881,-1,"NM_144647","CAPSL",133690,0.273623481,-1.47293291,2.035016719,0.157184109,0.535778268,"up"]
["ENSG00000133606.6",7,140152840,140179369,-1,"NM_013446","MKRN1",23608,-0.099458755,6.165446193,2.031735769,0.157515325,0.536125483,"down"]
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["ENSG00000186399.8",15,30695943,30706463,-1,"NM_001282484","GOLGA8R",101059918,0.193853298,1.654062135,2.024314192,0.158267518,0.53701014,"up"]
["ENSG00000134419.11",16,18792617,18801705,-1,"NM_001019","RPS15A",6210,0.104495551,6.076075665,2.021430428,0.158560912,0.537095503,"up"]
["ENSG00000078967.8",7,43966037,43995735,1,"NA","UBE2D4",51619,-0.068056015,4.621713917,2.016550967,0.15905878,0.537965858,"down"]
["ENSG00000231741.2",9,88549503,88551514,1,"NA","NA","NA",0.327889039,-1.441193298,2.016203916,0.15909426,0.538023278,"up"]
["ENSG00000180336.13",17,42733762,42767676,1,"NA","C17orf104",284071,-0.119837641,1.440611766,2.012435588,0.15948009,0.538473767,"down"]
["ENSG00000163915.3",3,185430316,185447575,1,"NA","C3orf65","NA",0.496587738,-2.859036209,2.009044252,0.159828247,0.538812991,"up"]
["ENSG00000268578.1",9,45441273,45441542,-1,"NA","NA","NA",0.4197839,-1.649475536,2.00296845,0.16045419,0.539552431,"up"]
["ENSG00000253539.1",8,100808843,100811415,-1,"NA","NA","NA",0.268038298,-1.932728082,2.001398186,0.160616424,0.539552431,"up"]
["ENSG00000120915.9",8,27348296,27403081,1,"NM_001979","EPHX2",2053,0.121895587,2.893543143,1.998689456,0.160896724,0.539636566,"up"]
["ENSG00000181638.13",8,144328991,144344875,1,"NM_001271156","ZFP41",286128,0.166373522,3.992218254,1.995542694,0.161223063,0.53999401,"up"]
["ENSG00000213694.3",9,91606362,91619925,1,"NM_005226","S1PR3",1903,0.186046927,2.659967691,1.990306622,0.161767776,0.540991754,"up"]
["ENSG00000154734.10",21,28208066,28217728,-1,"NM_006988","ADAMTS1",9510,0.257245816,4.834286031,1.987747899,0.162034737,0.541005414,"up"]
["ENSG00000006625.13",7,30536237,30591095,-1,"NA","GGCT",79017,-0.149594174,4.382214415,1.984419168,0.162382799,0.541375254,"down"]
["ENSG00000238025.1",13,43507994,43509028,1,"NA","ZDHHC4P1","NA",0.358162175,-1.988747465,1.9802342,0.162821621,0.542003265,"up"]
["ENSG00000134330.14",2,9613787,9636672,1,"NA","IAH1",285148,-0.079371762,4.582663328,1.97628553,0.163236926,0.542730026,"down"]
["ENSG00000183307.3",22,17597189,17602257,-1,"NM_001163079","CECR6",27439,-0.186708382,4.771066705,1.969039161,0.164002266,0.544090557,"down"]
["ENSG00000173456.4",11,119205237,119208023,1,"NM_032015","RNF26",79102,-0.123823617,3.75155164,1.964426165,0.164491645,0.544860669,"down"]
["ENSG00000267586.2",18,39739247,40271387,1,"NA","LINC00907",284260,-0.17911431,-0.473366351,1.961395131,0.16481412,0.545099404,"down"]
["ENSG00000167552.9",12,49578579,49583107,-1,"NM_006009","TUBA1A",7846,-0.184923183,9.189652653,1.959005388,0.165068884,0.545165435,"down"]
["ENSG00000176160.5",17,56497528,56565745,-1,"NM_001080439","HSF5",124535,0.260616903,-1.382981868,1.955032565,0.165493428,0.545686441,"up"]
["ENSG00000235731.1",15,25729978,25823938,-1,"NA","NA","NA",0.217961283,-0.106662393,1.951208906,0.16590323,0.546212183,"up"]
["ENSG00000255108.1",11,823634,832883,-1,"NA","NA","NA",0.487738539,-2.981365331,1.947889319,0.166259963,0.546561883,"up"]
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["ENSG00000100983.5",20,33516236,33543620,-1,"NM_000178","GSS",2937,-0.108234929,4.704688307,1.936223831,0.167520658,0.548886771,"down"]
["ENSG00000111640.10",12,6643093,6647537,1,"NM_002046","GAPDH",2597,-0.097434353,10.01354038,1.933812099,0.167782679,0.54892092,"down"]
["ENSG00000262601.1",16,85204882,85218969,1,"NA","NA","NA",0.284505314,-0.70224444,1.929913584,0.168207239,0.549448903,"up"]
["ENSG00000134326.7",2,6980701,7006766,-1,"NM_207315","CMPK2",129607,0.203222331,3.300123819,1.926548367,0.168574726,0.549863098,"up"]
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["ENSG00000205177.5",11,33719807,33722347,-1,"NM_001166692","C11orf91",100131378,0.48120314,-3.00531368,1.912439218,0.17012567,0.550695615,"up"]
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["ENSG00000186638.11",9,34252379,34329198,-1,"NA","KIF24",347240,0.101977057,2.03101805,1.877004506,0.174094702,0.555190449,"up"]
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["ENSG00000051341.9",3,121150278,121264853,-1,"NM_199420","POLQ",10721,0.148741196,1.408129471,1.778640375,0.185693231,0.567060144,"up"]
["ENSG00000268047.1",19,50356144,50358224,-1,"NA","NA","NA",0.327107829,-2.509750665,1.775407502,0.18608958,0.567395457,"up"]
["ENSG00000215493.3",22,20804409,20806111,1,"NA","NA","NA",0.154573706,1.405319538,1.772880038,0.186400142,0.567665274,"up"]
["ENSG00000107796.8",10,90694831,90751147,-1,"NM_001613","ACTA2",59,-0.235094387,3.613108433,1.769721449,0.186789111,0.568004131,"down"]
["ENSG00000167733.9",19,5680615,5688533,1,"NA","HSD11B1L",374875,-0.107349636,5.361419399,1.765790759,0.1872745,0.568687509,"down"]
["ENSG00000130305.12",7,72716514,72722864,-1,"NM_001168348","NSUN5",55695,-0.083058445,3.158700471,1.760734864,0.187901026,0.569614997,"down"]
["ENSG00000231181.1",1,9636485,9637043,1,"NA","NA","NA",0.237943084,-1.521021402,1.756980753,0.188367836,0.570065439,"up"]
["ENSG00000178972.3",4,144256418,144258970,-1,"NA","NA","NA",0.202325357,1.728526335,1.754854127,0.188632882,0.570065439,"up"]
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["ENSG00000240509.1",8,94969566,94969919,-1,"NA","RPL34P18","NA",0.00079312,-3.029937774,{"v":1.77e-07,"d":"1.77E-07"},0.999665596,0.999984622,"up"]
["ENSG00000253205.1",8,64297397,64382763,-1,"NA","NA","NA",{"v":5.21e-05,"d":"5.21E-05"},-2.438170857,{"v":1.33e-07,"d":"1.33E-07"},0.999709861,0.999984622,"up"]
["ENSG00000140538.12",15,88418230,88799999,-1,"NM_002530","NTRK3",4916,{"v":1.91E-5,"d":"1.91E-05"},6.844769876,{"v":1.15E-7,"d":"1.15E-07"},0.999730444,0.999984622,"up"]
["ENSG00000146834.9",7,100026413,100031741,1,"NA","MEPCE",56257,{"v":1.59E-5,"d":"1.59E-05"},4.420275725,{"v":7.78e-08,"d":"7.78E-08"},0.999778073,0.999984622,"up"]
["ENSG00000196150.9",8,146076632,146127553,-1,"NA","ZNF250",58500,{"v":1.1E-5,"d":"1.10E-05"},4.304651642,{"v":5.98e-08,"d":"5.98E-08"},0.999805393,0.999984622,"up"]
["ENSG00000244968.2",5,38556888,38671318,1,"NA","LIFR-AS1",100506495,{"v":1.69e-05,"d":"1.69E-05"},2.580188867,{"v":4.68e-08,"d":"4.68E-08"},0.999827858,0.999984622,"up"]
["ENSG00000167193.7",17,1323983,1366456,-1,"NM_005206","CRK",1398,{"v":-1.09e-05,"d":"-1.09E-05"},6.178812723,{"v":2.32e-08,"d":"2.32E-08"},0.999878784,0.999984622,"down"]
["ENSG00000214525.4",2,68755373,68756584,-1,"NA","NA","NA",0.000461472,-1.858775426,{"v":1.32e-08,"d":"1.32E-08"},0.999908651,0.999984622,"up"]
["ENSG00000196968.6",10,75532049,75540009,1,"NM_173540","FUT11",170384,{"v":3.89E-6,"d":"3.89E-06"},4.101477075,{"v":5.45E-9,"d":"5.45E-09"},0.999941258,0.999984622,"up"]
["ENSG00000230565.1",10,44141390,44143467,1,"NA","ZNF32-AS2",414208,{"v":-5.45e-06,"d":"-5.45E-06"},-0.895573765,{"v":5.12e-09,"d":"5.12E-09"},0.99994309,0.999984622,"down"]
["ENSG00000234855.1",10,98862513,98863504,1,"NA","NA",100505540,-0.00103774,-2.272099853,{"v":2.23E-9,"d":"2.23E-09"},0.999962428,0.999984622,"down"]
["ENSG00000250979.1",8,73114986,73163800,-1,"NA","NA","NA",2.75829E-4,-1.091685017,3.74E-10,0.999984622,0.999984622,"up"]

{"sheet":"Reactome enrichments","index":2,"n_rows":110,"n_cols":12,"rows_kept":110}
[null,"Cluster","direction","ID","Description","GeneRatio","BgRatio","pvalue","p.adjust","qvalue","geneID","Count"]
[1,"up","up","R-HSA-6783783","Interleukin-10 signaling","19/428","47/10704",4.57063776167756e-15,4.03130250579961e-12,3.35821595542204E-12,"IL1B/IL1RN/ICAM1/CCL4/CXCL1/IL6/CD80/CCL2/CSF3/CXCL8/FPR1/CCL4L1/CXCL10/TNFRSF1A/TIMP1/LIF/CCL3/IL10RA/CSF1",19]
[2,"up","up","R-HSA-449147","Signaling by Interleukins","54/428","461/10704",6.5116629359856e-13,2.87164335476965E-10,2.39217933121997e-10,"IL1B/H3C13/IL1RN/H3C7/ICAM1/IL21R/CCL4/ELK1/NFKB2/CDKN1A/CXCL1/HMOX1/BATF/IL6/MMP3/CD80/OSM/CCL2/CSF3/CEBPD/CXCL8/FPR1/LGALS9/PIM1/CCL4L1/SOCS3/VIM/SDC1/MYC/SOX2/CISH/CXCL10/TNFRSF1A/TIMP1/RELA/LIF/MAPKAPK3/CSF2RB/ITGB2/CCL3/TNIP2/MSN/MAPKAPK2/IL10RA/BIRC5/IRAK2/LCP1/CSF1/MYD88/BCL6/JAK3/HGF/IL32/HCK",54]
[3,"up","up","R-HSA-6785807","Interleukin-4 and Interleukin-13 signaling","23/428","108/10704",3.05441767724957e-11,8.97998797111374e-09,7.48064399550948e-09,"IL1B/ICAM1/CDKN1A/HMOX1/BATF/IL6/MMP3/OSM/CCL2/CEBPD/CXCL8/PIM1/SOCS3/VIM/MYC/SOX2/TIMP1/LIF/ITGB2/BIRC5/BCL6/JAK3/HGF",23]
[4,"up","up","R-HSA-877300","Interferon gamma signaling","21/428","91/10704",4.46353593319039e-11,9.8420967326848e-09,8.19881074043918e-09,"ICAM1/CD44/IRF7/GBP2/IFI30/GBP3/TRIM25/SOCS3/MID1/GBP1/HLA-B/OAS3/TRIM5/MT2A/TRIM21/PML/HLA-A/OASL/TRIM14/HLA-F/IRF9",21]
[5,"up","up","R-HSA-6798695","Neutrophil degranulation","51/428","480/10704",1.16330589353991E-10,2.0520715962044e-08,1.70944739724391e-08,"PLAUR/HSPA1B/CD14/CHI3L1/CXCL1/SERPINA1/SIGLEC9/BST2/CD44/FCAR/C5AR1/FTL/LRG1/FPR1/ORM2/GSDMD/HEBP2/FCGR2A/LGALS3/LTF/SERPINA3/ITGAL/S100A11/CYFIP1/HK3/HVCN1/CD68/HLA-B/GPR84/PYGL/ITGB2/SLC11A1/PNP/MGST1/OSCAR/RNASE2/NBEAL2/PPBP/TLR2/SIGLEC14/NFAM1/DOK3/PLEKHO2/HLA-A/CD300A/VNN1/FABP5/TCIRG1/FPR2/ABCA13/CLEC5A",51]
[6,"up","up","R-HSA-913531","Interferon Signaling","28/428","199/10704",5.61047510822373e-09,8.24739840908888e-07,6.87037127287748e-07,"IFI6/ICAM1/ISG15/BST2/CD44/IRF7/GBP2/IFI30/UBE2L6/GBP3/TRIM25/SOCS3/MID1/GBP1/HLA-B/OAS3/TRIM5/IFITM3/MT2A/TRIM21/PML/HLA-A/HERC5/OASL/TRIM14/IFI35/HLA-F/IRF9",28]
[7,"up","up","R-HSA-9616222","Transcriptional regulation of granulopoiesis","18/428","90/10704",1.27317275741819E-8,1.60419767434691E-6,1.33635275891413E-6,"H3C13/H2AC14/H3C7/H2BC9/SPI1/CDKN1A/H2BC21/H2AC4/MYC/H2BC11/H4C15/H2BC17/H2AC19/CDK2/PML/H2BC14/H2BC3/CEBPB",18]
[8,"up","up","R-HSA-2559582","Senescence-Associated Secretory Phenotype (SASP)","20/428","112/10704",1.52989895042353e-08,1.68671359284194E-6,1.40509140446793e-06,"H3C13/H2AC14/H3C7/H2BC9/UBE2C/CDKN1A/IL6/H2BC21/H2AC4/CXCL8/H2BC11/H4C15/H2BC17/CDKN2C/RELA/H2AC19/CDK2/H2BC14/H2BC3/CEBPB",20]
[9,"up","up","R-HSA-3214815","HDACs deacetylate histones","17/428","94/10704",1.53497786839219E-7,1.50427831102435e-05,1.25311643524883E-5,"H3C13/H2AC14/H2AC12/H3C7/H2BC9/H2BC21/H2BC18/H2AC4/H2BC11/H4C15/H2BC17/TBL1X/HDAC1/H2AC19/HMG20B/H2BC14/H2BC3",17]
[10,"up","up","R-HSA-2559583","Cellular Senescence","25/428","197/10704",2.9043833161377e-07,2.56166608483345E-5,2.13395742596223E-5,"H3C13/H2AC14/H1-5/H1-2/H3C7/H2BC9/UBE2C/CDKN1A/IL6/H2BC21/H2AC4/CXCL8/H2BC11/H4C15/H2BC17/CDKN2C/RELA/MAPKAPK3/H1-3/H2AC19/CDK2/MAPKAPK2/H2BC14/H2BC3/CEBPB",25]
[11,"up","up","R-HSA-9609690","HCMV Early Events","20/428","135/10704",3.78587982746631E-7,3.03558727984116e-05,2.52875035365692e-05,"H3C13/H2AC14/H2AC12/H3C7/H2BC9/ELK1/H2BC21/H2BC18/H2AC4/H2BC11/H4C15/TUBB1/H2BC17/TBL1X/TUBB2B/H2AC19/PML/TUBB6/H2BC14/H2BC3",20]
[12,"up","up","R-HSA-2559586","DNA Damage/Telomere Stress Induced Senescence","15/428","80/10704",5.10326087053551E-7,3.64413041019764e-05,3.03568806100723e-05,"H2AC14/H1-5/H1-2/H2BC9/CDKN1A/H2BC21/H2AC4/H2BC11/H4C15/H2BC17/H1-3/H2AC19/CDK2/H2BC14/H2BC3",15]
[13,"up","up","R-HSA-909733","Interferon alpha/beta signaling","14/428","70/10704",5.37116727126637e-07,3.64413041019764e-05,3.03568806100723e-05,"IFI6/ISG15/BST2/IRF7/GBP2/SOCS3/HLA-B/OAS3/IFITM3/HLA-A/OASL/IFI35/HLA-F/IRF9",14]
[14,"up","up","R-HSA-606279","Deposition of new CENPA-containing nucleosomes at the centromere","14/428","74/10704",1.09481680795823e-06,6.41855748141467e-05,5.34688282853257E-5,"H2AC14/H2BC9/H2BC21/CENPA/H2AC4/KNL1/H2BC11/H4C15/CENPM/H2BC17/H2AC19/H2BC14/HJURP/H2BC3",14]
[15,"up","up","R-HSA-774815","Nucleosome assembly","14/428","74/10704",1.09481680795823e-06,6.41855748141467e-05,5.34688282853257E-5,"H2AC14/H2BC9/H2BC21/CENPA/H2AC4/KNL1/H2BC11/H4C15/CENPM/H2BC17/H2AC19/H2BC14/HJURP/H2BC3",14]
[16,"up","up","R-HSA-198933","Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell","19/428","132/10704",1.16436416896411e-06,6.41855748141467e-05,5.34688282853257E-5,"ICAM1/SIGLEC9/SIGLEC1/SIGLEC7/MICA/ITGAL/FCGR3A/LILRB1/HLA-B/MICB/ITGB2/OSCAR/CD300LB/HLA-A/CD40/CD300A/HCST/NECTIN2/HLA-F",19]
[17,"up","up","R-HSA-9609646","HCMV Infection","21/428","160/10704",1.5070753092178E-6,7.81906131017707e-05,6.51355149123236E-5,"H3C13/H2AC14/H2AC12/H3C7/H2BC9/ELK1/H2BC21/H2BC18/H2AC4/CEBPD/H2BC11/H4C15/TUBB1/H2BC17/TBL1X/TUBB2B/H2AC19/PML/TUBB6/H2BC14/H2BC3",21]
[18,"up","up","R-HSA-166663","Initial triggering of complement","8/428","23/10704",1.76765730288829E-6,8.6615207841526e-05,7.21534969249137e-05,"C1QB/C1QC/C1R/C1S/C2/C4B_2/C4B/C1QA",8]
[19,"up","up","R-HSA-195258","RHO GTPase Effectors","32/428","327/10704",2.51980774464215e-06,1.16972127935494E-4,9.74418728953032e-05,"SFN/H3C13/H2AC14/H3C7/H2BC9/H2BC21/CENPA/H2AC4/KIF14/AURKB/LIMK2/KNL1/H2BC11/H4C15/CENPM/NDC80/TUBB1/H2BC17/CYFIP1/RAC2/PLK1/TUBB2B/H2AC19/RHOD/RHOC/KIF18A/BUB1/BIRC5/BUB1B/TUBB6/H2BC14/H2BC3",32]
[20,"up","up","R-HSA-73728","RNA Polymerase I Promoter Opening","12/428","63/10704",5.9869126928028e-06,0.000264022849752603,0.000219940266293492,"H3C13/H2AC14/H3C7/H2BC9/H2BC21/H2AC4/H2BC11/H4C15/H2BC17/H2AC19/H2BC14/H2BC3",12]
[21,"up","up","R-HSA-2299718","Condensation of Prophase Chromosomes","13/428","74/10704",6.29250146392307e-06,2.64285061484769E-4,0.000220158697835504,"H3C13/H2AC14/H3C7/H2BC9/H2BC21/H2AC4/H2BC11/H4C15/H2BC17/PLK1/H2AC19/H2BC14/H2BC3",13]
[22,"up","up","R-HSA-5334118","DNA methylation","12/428","65/10704",8.4047442117703E-6,0.000327409319019114,0.000272743411714216,"H3C13/H2AC14/H3C7/H2BC9/H2BC21/H2AC4/H2BC11/H4C15/H2BC17/H2AC19/H2BC14/H2BC3",12]
[23,"up","up","R-HSA-427389","ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression","13/428","76/10704",8.53788473632609e-06,0.000327409319019114,0.000272743411714216,"H3C13/H2AC14/H3C7/H2BC9/H2BC21/H2AC4/H2BC11/H4C15/H2BC17/HDAC1/H2AC19/H2BC14/H2BC3",13]
[24,"up","up","R-HSA-5625886","Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3","12/428","67/10704",1.16387766587947E-5,0.000427725042210706,0.00035630991701047,"H3C13/H2AC14/H3C7/H2BC9/H2BC21/H2AC4/H2BC11/H4C15/H2BC17/H2AC19/H2BC14/H2BC3",12]
[25,"up","up","R-HSA-427359","SIRT1 negatively regulates rRNA expression","12/428","68/10704",1.36299248368134E-5,4.67480617180388E-4,0.000389427701148002,"H3C13/H2AC14/H3C7/H2BC9/H2BC21/H2AC4/H2BC11/H4C15/H2BC17/H2AC19/H2BC14/H2BC3",12]
[26,"up","up","R-HSA-201722","Formation of the beta-catenin:TCF transactivating complex","14/428","91/10704",1.37806077626872e-05,4.67480617180388E-4,0.000389427701148002,"H3C13/H2AC14/H3C7/H2BC9/H2BC21/H2AC4/MYC/H2BC11/H4C15/H2BC17/HDAC1/H2AC19/H2BC14/H2BC3",14]
[27,"up","up","R-HSA-5625740","RHO GTPases activate PKNs","14/428","95/10704",2.27888029646352e-05,0.000744434230178085,0.000620139745392413,"SFN/H3C13/H2AC14/H3C7/H2BC9/H2BC21/H2AC4/H2BC11/H4C15/H2BC17/H2AC19/RHOC/H2BC14/H2BC3",14]
[28,"up","up","R-HSA-212300","PRC2 methylates histones and DNA","12/428","73/10704",2.87141014473187e-05,0.000881601062831581,0.000734404513493786,"H3C13/H2AC14/H3C7/H2BC9/H2BC21/H2AC4/H2BC11/H4C15/H2BC17/H2AC19/H2BC14/H2BC3",12]
[29,"up","up","R-HSA-8936459","RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function","14/428","97/10704",2.89868830182719e-05,0.000881601062831581,0.000734404513493786,"H3C13/H2AC14/H3C7/H2BC9/THBS1/H2BC21/H2AC4/H2BC11/H4C15/H2BC17/HDAC1/H2AC19/H2BC14/H2BC3",14]
[30,"up","up","R-HSA-171306","Packaging Of Telomere Ends","10/428","52/10704",3.29187144076848e-05,0.000962375082127436,0.000801692096103294,"H2AC14/H2BC9/H2BC21/H2AC4/H2BC11/H4C15/H2BC17/H2AC19/H2BC14/H2BC3",10]
[31,"up","up","R-HSA-912446","Meiotic recombination","13/428","86/10704",3.3824974541894e-05,0.000962375082127436,0.000801692096103294,"H3C13/H2AC14/H3C7/H2BC9/H2BC21/H2AC4/H2BC11/H4C15/H2BC17/H2AC19/CDK2/H2BC14/H2BC3",13]
[32,"up","up","R-HSA-9610379","HCMV Late Events","15/428","116/10704",5.66573423468949e-05,1.56161799843629E-3,0.00130088239993857,"H3C13/H2AC14/H2AC12/H3C7/H2BC9/H2BC21/H2BC18/H2AC4/CEBPD/H2BC11/H4C15/H2BC17/H2AC19/H2BC14/H2BC3",15]
[33,"up","up","R-HSA-110330","Recognition and association of DNA glycosylase with site containing an affected purine","10/428","56/10704",6.42164368514801e-05,0.0016182542086573,0.00134806234352881,"H2AC14/H2BC9/H2BC21/H2AC4/H2BC11/H4C15/H2BC17/H2AC19/H2BC14/H2BC3",10]
[34,"up","up","R-HSA-110331","Cleavage of the damaged purine","10/428","56/10704",6.42164368514801e-05,0.0016182542086573,0.00134806234352881,"H2AC14/H2BC9/H2BC21/H2AC4/H2BC11/H4C15/H2BC17/H2AC19/H2BC14/H2BC3",10]
[35,"up","up","R-HSA-73927","Depurination","10/428","56/10704",6.42164368514801e-05,0.0016182542086573,0.00134806234352881,"H2AC14/H2BC9/H2BC21/H2AC4/H2BC11/H4C15/H2BC17/H2AC19/H2BC14/H2BC3",10]
[36,"up","up","R-HSA-194315","Signaling by Rho GTPases","36/428","455/10704",6.85620199411356e-05,0.00167976948855782,1.39930672277522E-3,"SFN/H3C13/H2AC14/H3C7/SRGAP1/H2BC9/H2BC21/CENPA/H2AC4/KIF14/AURKB/LIMK2/KNL1/H2BC11/H4C15/CENPM/ARHGEF5/ARHGAP6/NDC80/TUBB1/H2BC17/CYFIP1/RAC2/ARHGEF26/PLK1/TUBB2B/H2AC19/RHOD/RHOC/KIF18A/BUB1/BIRC5/BUB1B/TUBB6/H2BC14/H2BC3",36]
[37,"up","up","R-HSA-1912408","Pre-NOTCH Transcription and Translation","13/428","93/10704",7.82380949105921E-5,1.86502701922006E-3,1.55363272397136E-3,"H3C13/H2AC14/H3C7/H2BC9/H2BC21/H2AC4/H2BC11/H4C15/H2BC17/H2AC19/NOTCH2/H2BC14/H2BC3",13]
[38,"up","up","R-HSA-977606","Regulation of Complement cascade","9/428","47/10704",8.45726509833085e-05,0.00196297574124416,0.00163522743452491,"C1QB/C5AR1/C1QC/C1R/C1S/C2/C4B_2/C4B/C1QA",9]
[39,"up","up","R-HSA-380108","Chemokine receptors bind chemokines","10/428","59/10704",1.01794337485523E-4,2.30211809390336E-3,1.91774487354642E-3,"CCL4/CXCL1/CXCL5/CCL2/CXCL8/CXCL3/CCL4L1/CXCL10/CCL3/PPBP",10]
[40,"up","up","R-HSA-1912422","Pre-NOTCH Expression and Processing","14/428","109/10704",0.000107345951306455,0.00236697822630734,0.00197177563189226,"H3C13/H2AC14/H3C7/H2BC9/H2BC21/H2AC4/H2BC11/H4C15/ATP2A1/H2BC17/H2AC19/NOTCH2/H2BC14/H2BC3",14]
[41,"up","up","R-HSA-977225","Amyloid fiber formation","14/428","110/10704",1.18606370120101E-4,0.00255148337672997,0.00212547487403929,"H3C13/H2AC14/H3C7/H2BC9/H2BC21/H2AC4/UBE2L6/H2BC11/H4C15/LTF/H2BC17/H2AC19/H2BC14/H2BC3",14]
[42,"up","up","R-HSA-2559580","Oxidative Stress Induced Senescence","15/428","125/10704",0.000134328955761454,0.00266635310350089,2.22116537324695E-3,"H3C13/H2AC14/H3C7/H2BC9/H2BC21/H2AC4/H2BC11/H4C15/H2BC17/CDKN2C/MAPKAPK3/H2AC19/MAPKAPK2/H2BC14/H2BC3",15]
[43,"up","up","R-HSA-110328","Recognition and association of DNA glycosylase with site containing an affected pyrimidine","10/428","61/10704",0.000136038423648004,0.00266635310350089,2.22116537324695E-3,"H2AC14/H2BC9/H2BC21/H2AC4/H2BC11/H4C15/H2BC17/H2AC19/H2BC14/H2BC3",10]
[44,"up","up","R-HSA-110329","Cleavage of the damaged pyrimidine ","10/428","61/10704",0.000136038423648004,0.00266635310350089,2.22116537324695E-3,"H2AC14/H2BC9/H2BC21/H2AC4/H2BC11/H4C15/H2BC17/H2AC19/H2BC14/H2BC3",10]
[45,"up","up","R-HSA-73928","Depyrimidination","10/428","61/10704",0.000136038423648004,0.00266635310350089,2.22116537324695E-3,"H2AC14/H2BC9/H2BC21/H2AC4/H2BC11/H4C15/H2BC17/H2AC19/H2BC14/H2BC3",10]
[46,"up","up","R-HSA-166786","Creation of C4 and C2 activators","5/428","14/10704",0.00014815375894911,2.84068729115468E-3,0.00236639184774551,"C1QB/C1QC/C1R/C1S/C1QA",5]
[47,"up","up","R-HSA-375276","Peptide ligand-binding receptors","20/428","201/10704",1.57046869241302E-4,0.00294713486533678,0.00245506639933772,"CCL4/CXCL1/CXCL5/C5AR1/CCL2/CXCL8/FPR1/CXCL3/CCL4L1/CXCL10/KISS1R/CCL3/TACR3/PPBP/MC1R/BDKRB1/MC4R/FPR2/GHSR/NTSR2",20]
[48,"up","up","R-HSA-9006931","Signaling by Nuclear Receptors","26/428","299/10704",1.62494814831323E-4,0.00298584222252556,0.00248731098140928,"H3C13/H2AC14/HSPB1/H3C7/H2BC9/ELK1/AKR1C3/H2BC21/H2AC4/MMP3/ABCA1/FOSB/MYC/H2BC11/H4C15/H2BC17/ZNF217/PLTP/TBL1X/APOE/HDAC1/H2AC19/SPHK1/H2BC14/FABP5/H2BC3",26]
[49,"up","up","R-HSA-68875","Mitotic Prophase","16/428","142/10704",0.000171192971951236,3.08147349512224E-3,2.56697517555236E-3,"H3C13/H2AC14/H3C7/H2BC9/H2BC21/H2AC4/NEK6/H2BC11/H4C15/H2BC17/PLK1/H2AC19/CCNB2/H2BC14/H2BC3/LPIN3",16]
[50,"up","up","R-HSA-73929","Base-Excision Repair, AP Site Formation","10/428","63/10704",1.79528012002221E-4,0.00316687413171919,0.00263811689215896,"H2AC14/H2BC9/H2BC21/H2AC4/H2BC11/H4C15/H2BC17/H2AC19/H2BC14/H2BC3",10]
[51,"up","up","R-HSA-9648025","EML4 and NUDC in mitotic spindle formation","14/428","117/10704",0.000230180934051708,0.00398077615360013,3.31612573721553E-3,"CENPA/NEK6/AURKB/KNL1/CENPM/NDC80/TUBB1/PLK1/TUBB2B/KIF18A/BUB1/BIRC5/BUB1B/TUBB6",14]
[52,"up","up","R-HSA-5250924","B-WICH complex positively regulates rRNA expression","12/428","91/10704",2.57228699081812E-4,0.00428067382245582,0.00356595098230596,"H3C13/H2AC14/H3C7/H2BC9/H2BC21/H2AC4/H2BC11/H4C15/H2BC17/H2AC19/H2BC14/H2BC3",12]
[53,"up","up","R-HSA-73772","RNA Polymerase I Promoter Escape","12/428","91/10704",2.57228699081812E-4,0.00428067382245582,0.00356595098230596,"H3C13/H2AC14/H3C7/H2BC9/H2BC21/H2AC4/H2BC11/H4C15/H2BC17/H2AC19/H2BC14/H2BC3",12]
[54,"up","up","R-HSA-5250913","Positive epigenetic regulation of rRNA expression","13/428","106/10704",0.000299510133322226,0.00489199884426302,0.00407520610251293,"H3C13/H2AC14/H3C7/H2BC9/H2BC21/H2AC4/H2BC11/H4C15/H2BC17/HDAC1/H2AC19/H2BC14/H2BC3",13]
[55,"up","up","R-HSA-68886","M Phase","32/428","418/10704",3.15853761344846E-4,0.00506514577283916,4.2194435486833E-3,"H3C13/H2AC14/H3C7/H2BC9/UBE2C/H2BC21/CENPA/H2AC4/NEK6/AURKB/KNL1/KIF20A/H2BC11/H4C15/CENPM/NDC80/TUBB1/H2BC17/PLK1/TUBB2B/CEP152/H2AC19/KIF18A/CCNB2/BUB1/BIRC5/BUB1B/TUBB6/H2BC14/H2BC3/NCAPG/LPIN3",32]
[56,"up","up","R-HSA-9018519","Estrogen-dependent gene expression","16/428","150/10704",0.000322466234811209,0.00507884319827654,0.00423085398304932,"H3C13/H2AC14/H3C7/H2BC9/H2BC21/H2AC4/FOSB/MYC/H2BC11/H4C15/H2BC17/ZNF217/HDAC1/H2AC19/H2BC14/H2BC3",16]
[57,"up","up","R-HSA-427413","NoRC negatively regulates rRNA expression","13/428","107/10704",0.000328819937804609,0.00508805587971342,0.00423852846883872,"H3C13/H2AC14/H3C7/H2BC9/H2BC21/H2AC4/H2BC11/H4C15/H2BC17/HDAC1/H2AC19/H2BC14/H2BC3",13]
[58,"up","up","R-HSA-9670095","Inhibition of DNA recombination at telomere","10/428","68/10704",3.41776120468663E-4,0.00519735410781657,4.32957771482989E-3,"H2AC14/H2BC9/H2BC21/H2AC4/H2BC11/H4C15/H2BC17/H2AC19/H2BC14/H2BC3",10]
[59,"up","up","R-HSA-5250941","Negative epigenetic regulation of rRNA expression","13/428","110/10704",0.000431844899185308,0.00634812001802403,0.00528820595844466,"H3C13/H2AC14/H3C7/H2BC9/H2BC21/H2AC4/H2BC11/H4C15/H2BC17/HDAC1/H2AC19/H2BC14/H2BC3",13]
[60,"up","up","R-HSA-73854","RNA Polymerase I Promoter Clearance","13/428","110/10704",0.000431844899185308,0.00634812001802403,0.00528820595844466,"H3C13/H2AC14/H3C7/H2BC9/H2BC21/H2AC4/H2BC11/H4C15/H2BC17/HDAC1/H2AC19/H2BC14/H2BC3",13]
[61,"up","up","R-HSA-166658","Complement cascade","9/428","58/10704",0.000447893599597701,0.00647610089910119,0.00539481850766515,"C1QB/C5AR1/C1QC/C1R/C1S/C2/C4B_2/C4B/C1QA",9]
[62,"up","up","R-HSA-5663220","RHO GTPases Activate Formins","15/428","140/10704",4.69157548234303E-4,0.00667414447649445,0.00555979573289548,"CENPA/AURKB/KNL1/CENPM/NDC80/TUBB1/PLK1/TUBB2B/RHOD/RHOC/KIF18A/BUB1/BIRC5/BUB1B/TUBB6",15]
[63,"up","up","R-HSA-2500257","Resolution of Sister Chromatid Cohesion","14/428","126/10704",0.000497582071755778,6.96614900458089E-3,0.00580304571571484,"CENPA/AURKB/KNL1/CENPM/NDC80/TUBB1/PLK1/TUBB2B/KIF18A/CCNB2/BUB1/BIRC5/BUB1B/TUBB6",14]
[64,"up","up","R-HSA-73886","Chromosome Maintenance","15/428","141/10704",0.000506252552409796,0.0069767929878975,0.00581191252602036,"H2AC14/H2BC9/H2BC21/CENPA/H2AC4/KNL1/H2BC11/H4C15/CENPM/H2BC17/H2AC19/CDK2/H2BC14/HJURP/H2BC3",15]
[65,"up","up","R-HSA-73864","RNA Polymerase I Transcription","13/428","112/10704",0.000514779167640461,0.00698515732090595,0.00581888030790351,"H3C13/H2AC14/H3C7/H2BC9/H2BC21/H2AC4/H2BC11/H4C15/H2BC17/HDAC1/H2AC19/H2BC14/H2BC3",13]
[66,"up","up","R-HSA-5676594","TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway","5/428","18/10704",0.0005552719413669,0.00742045230735767,0.00618149625317538,"TNFSF14/LTBR/LTA/TNFRSF12A/CD40",5]
[67,"up","up","R-HSA-8878171","Transcriptional regulation by RUNX1","21/428","239/10704",0.000595391408041111,0.0078378391327203,0.00652919407404078,"H3C13/H2AC14/H3C7/H2BC9/SPI1/THBS1/H2BC21/H2AC4/SOCS3/H2BC11/H4C15/LGALS3/H2BC17/YAP1/SMARCD3/HDAC1/H2AC19/PML/BLK/H2BC14/H2BC3",21]
[68,"up","up","R-HSA-8939211","ESR-mediated signaling","20/428","223/10704",0.000616458378106566,0.00799582778661752,0.00666080414734339,"H3C13/H2AC14/HSPB1/H3C7/H2BC9/ELK1/H2BC21/H2AC4/MMP3/FOSB/MYC/H2BC11/H4C15/H2BC17/ZNF217/HDAC1/H2AC19/SPHK1/H2BC14/H2BC3",20]
[69,"up","up","R-HSA-8939236","RUNX1 regulates transcription of genes involved in differentiation of HSCs","14/428","130/10704",0.000682811264648485,0.00872810920898498,0.00727082017886563,"H3C13/H2AC14/H3C7/H2BC9/SPI1/H2BC21/H2AC4/H2BC11/H4C15/H2BC17/YAP1/H2AC19/H2BC14/H2BC3",14]
[70,"up","up","R-HSA-69620","Cell Cycle Checkpoints","24/428","294/10704",0.00072123748785139,0.00908759234692752,0.00757028220331234,"SFN/H2BC9/UBE2C/CDKN1A/H2BC21/CENPA/AURKB/KNL1/MCM10/H2BC11/H4C15/CENPM/WEE1/NDC80/H2BC17/PLK1/KIF18A/CDK2/CCNB2/BUB1/BIRC5/BUB1B/H2BC14/H2BC3",24]
[71,"up","up","R-HSA-1500620","Meiosis","13/428","118/10704",0.000848740918644702,0.0104859927322309,0.00873519862405681,"H3C13/H2AC14/H3C7/H2BC9/H2BC21/H2AC4/H2BC11/H4C15/H2BC17/H2AC19/CDK2/H2BC14/H2BC3",13]
[72,"up","up","R-HSA-420029","Tight junction interactions","6/428","29/10704",0.00085599940671273,0.0104859927322309,0.00873519862405681,"CLDN19/PARD6G/PARD3/CLDN23/CRB3/CLDN2",6]
[73,"up","up","R-HSA-500792","GPCR ligand binding","33/428","467/10704",1.04230181039853E-3,0.0124696395403167,0.0103876457800944,"CCL4/CXCL1/CXCL5/C5AR1/SMO/GPBAR1/CCL2/CXCL8/FPR1/CXCL3/CCL4L1/CXCL10/KISS1R/GPR65/ADM/LHCGR/CCL3/TACR3/HCAR3/ADM2/ADGRE1/PPBP/MC1R/RAMP1/TAS2R38/BDKRB1/MC4R/HCAR2/FPR2/GHSR/WNT9B/WNT11/NTSR2",33]
[74,"up","up","R-HSA-5578749","Transcriptional regulation by small RNAs","12/428","106/10704",0.00104620558501524,0.0124696395403167,0.0103876457800944,"H3C13/H2AC14/H3C7/H2BC9/H2BC21/H2AC4/H2BC11/H4C15/H2BC17/H2AC19/H2BC14/H2BC3",12]
[75,"up","up","R-HSA-1221632","Meiotic synapsis","10/428","79/10704",1.14568996859556E-3,0.0134733140306838,0.0112237417274344,"H2AC14/H2BC9/H2BC21/H2AC4/H2BC11/H4C15/H2BC17/H2AC19/H2BC14/H2BC3",10]
[76,"up","up","R-HSA-168181","Toll Like Receptor 7/8 (TLR7/8) Cascade","11/428","93/10704",0.00116679427820715,0.0135409546497199,0.0112800887283739,"CD14/ELK1/NFKB2/IRF7/TLR8/RELA/MAPKAPK3/TNIP2/MAPKAPK2/IRAK2/MYD88",11]
[77,"up","up","R-HSA-3214847","HATs acetylate histones","14/428","142/10704",0.00162207081915936,0.0185800839285527,0.0154778596277954,"H3C13/H2AC14/H2AC12/H3C7/H2BC9/H2BC21/H2BC18/H2AC4/H2BC11/H4C15/H2BC17/H2AC19/H2BC14/H2BC3",14]
[78,"up","up","R-HSA-1474165","Reproduction","14/428","143/10704",1.73429423546402E-3,0.0196108655856317,0.0163365367929,"H3C13/H2AC14/H3C7/H2BC9/H2BC21/H2AC4/H2BC11/H4C15/H2BC17/HVCN1/H2AC19/CDK2/H2BC14/H2BC3",14]
[79,"up","up","R-HSA-166016","Toll Like Receptor 4 (TLR4) Cascade","13/428","129/10704",1.93260087283098E-3,0.0215766325295813,0.0179740893968824,"CD180/CD14/ELK1/NFKB2/IRF7/RELA/MAPKAPK3/ITGB2/TNIP2/MAPKAPK2/TLR2/IRAK2/MYD88",13]
[80,"up","up","R-HSA-373076","Class A/1 (Rhodopsin-like receptors)","25/428","335/10704",0.0020018984148517,0.02207093002374,0.0183858564942959,"CCL4/CXCL1/CXCL5/C5AR1/GPBAR1/CCL2/CXCL8/FPR1/CXCL3/CCL4L1/CXCL10/KISS1R/GPR65/LHCGR/CCL3/TACR3/HCAR3/PPBP/MC1R/BDKRB1/MC4R/HCAR2/FPR2/GHSR/NTSR2",25]
[81,"up","up","R-HSA-936440","Negative regulators of DDX58/IFIH1 signaling","6/428","34/10704",0.00204697576757879,0.0222892916914135,0.0185677593992202,"ISG15/UBE2L6/TRIM25/IFIH1/TNFAIP3/HERC5",6]
[82,"up","up","R-HSA-5260271","Diseases of Immune System","5/428","24/10704",0.00225974661980397,0.0240132110682783,0.0200038445228049,"CD14/NFKB2/RELA/TLR2/MYD88",5]
[83,"up","up","R-HSA-5602358","Diseases associated with the TLR signaling cascade","5/428","24/10704",0.00225974661980397,0.0240132110682783,0.0200038445228049,"CD14/NFKB2/RELA/TLR2/MYD88",5]
[84,"up","up","R-HSA-157118","Signaling by NOTCH","19/428","236/10704",2.93579788356251E-3,0.0308258777774064,0.0256790341193814,"H3C13/H2AC14/H3C7/H2BC9/MDK/H2BC21/H2AC4/DLGAP5/MYC/H2BC11/H4C15/ATP2A1/H2BC17/TBL1X/HDAC1/H2AC19/NOTCH2/H2BC14/H2BC3",19]
[85,"up","up","R-HSA-983231","Factors involved in megakaryocyte development and platelet production","15/428","168/10704",0.00299064703730306,0.0310323610223682,0.0258510418828178,"H3C13/H3C7/MAFF/KIF20A/KIFC1/WEE1/TUBB1/KIF18B/TUBB2B/HDAC1/KIF18A/CDK2/HMG20B/TUBB6/CARMIL1",15]
[86,"up","up","R-HSA-156711","Polo-like kinase mediated events","4/428","16/10704",0.00312718614494636,0.0320718393004964,0.0267169636373631,"MYBL2/WEE1/PLK1/CCNB2",4]
[87,"up","up","R-HSA-5617472","Activation of anterior HOX genes in hindbrain development during early embryogenesis","12/428","121/10704",0.00325139025244361,0.0325877977574462,0.0271467750742301,"H3C13/H2AC14/H3C7/H2BC9/H2BC21/H2AC4/H2BC11/H4C15/H2BC17/H2AC19/H2BC14/H2BC3",12]
[88,"up","up","R-HSA-5619507","Activation of HOX genes during differentiation","12/428","121/10704",0.00325139025244361,0.0325877977574462,0.0271467750742301,"H3C13/H2AC14/H3C7/H2BC9/H2BC21/H2AC4/H2BC11/H4C15/H2BC17/H2AC19/H2BC14/H2BC3",12]
[89,"up","up","R-HSA-68877","Mitotic Prometaphase","17/428","204/10704",3.36310878975849E-3,0.0333287859838987,0.027764044178018,"CENPA/NEK6/AURKB/KNL1/CENPM/NDC80/TUBB1/PLK1/TUBB2B/CEP152/KIF18A/CCNB2/BUB1/BIRC5/BUB1B/TUBB6/NCAPG",17]
[90,"up","up","R-HSA-73884","Base Excision Repair","10/428","92/10704",0.0036208743350422,0.035094628170409,0.0292350524680099,"H2AC14/H2BC9/H2BC21/H2AC4/H2BC11/H4C15/H2BC17/H2AC19/H2BC14/H2BC3",10]
[91,"up","up","R-HSA-975155","MyD88 dependent cascade initiated on endosome","10/428","92/10704",0.0036208743350422,0.035094628170409,0.0292350524680099,"CD14/ELK1/NFKB2/IRF7/RELA/MAPKAPK3/TNIP2/MAPKAPK2/IRAK2/MYD88",10]
[92,"up","up","R-HSA-168898","Toll-like Receptor Cascades","14/428","155/10704",0.00366282782721971,0.0351153711261715,0.0292523320755075,"CD180/CD14/ELK1/NFKB2/IRF7/TLR8/RELA/MAPKAPK3/ITGB2/TNIP2/MAPKAPK2/TLR2/IRAK2/MYD88",14]
[93,"up","up","R-HSA-168928","DDX58/IFIH1-mediated induction of interferon-alpha/beta","9/428","78/10704",0.00379859708067922,0.0360254045716029,0.0300104217579411,"ISG15/NFKB2/IRF7/UBE2L6/TRIM25/IFIH1/RELA/TNFAIP3/HERC5",9]
[94,"up","up","R-HSA-1368108","BMAL1:CLOCK,NPAS2 activates circadian gene expression","5/428","27/10704",3.88928671537216E-3,0.0361089566627184,0.030080023571521,"TBL1X/SMARCD3/HELZ2/KLF15/SERPINE1",5]
[95,"up","up","R-HSA-1538133","G0 and Early G1","5/428","27/10704",3.88928671537216E-3,0.0361089566627184,0.030080023571521,"TOP2A/MYBL2/MYC/HDAC1/CDK2",5]
[96,"up","up","R-HSA-166058","MyD88:MAL(TIRAP) cascade initiated on plasma membrane","10/428","95/10704",0.00456505386326204,0.0415090464680115,0.0345784872116864,"CD14/ELK1/NFKB2/RELA/MAPKAPK3/TNIP2/MAPKAPK2/TLR2/IRAK2/MYD88",10]
[97,"up","up","R-HSA-168188","Toll Like Receptor TLR6:TLR2 Cascade","10/428","95/10704",0.00456505386326204,0.0415090464680115,0.0345784872116864,"CD14/ELK1/NFKB2/RELA/MAPKAPK3/TNIP2/MAPKAPK2/TLR2/IRAK2/MYD88",10]
[98,"up","up","R-HSA-141424","Amplification of signal from the kinetochores","10/428","96/10704",0.00491952466793861,0.0433902075712186,0.0361455601918016,"CENPA/AURKB/KNL1/CENPM/NDC80/PLK1/KIF18A/BUB1/BIRC5/BUB1B",10]
[99,"up","up","R-HSA-141444","Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal","10/428","96/10704",0.00491952466793861,0.0433902075712186,0.0361455601918016,"CENPA/AURKB/KNL1/CENPM/NDC80/PLK1/KIF18A/BUB1/BIRC5/BUB1B",10]
[100,"up","up","R-HSA-168138","Toll Like Receptor 9 (TLR9) Cascade","10/428","96/10704",0.00491952466793861,0.0433902075712186,0.0361455601918016,"CD14/ELK1/NFKB2/IRF7/RELA/MAPKAPK3/TNIP2/MAPKAPK2/IRAK2/MYD88",10]
[101,"up","up","R-HSA-5669034","TNFs bind their physiological receptors","5/428","29/10704",0.00535838978047903,0.0463385883357048,0.0386016644686979,"TNFSF14/TNFRSF11B/TNFRSF1A/LTA/TNFRSF8",5]
[102,"up","up","R-HSA-114608","Platelet degranulation ","12/428","129/10704",0.00546265565555799,0.0463385883357048,0.0386016644686979,"SERPINA1/THBS1/FERMT3/ORM2/SERPINA3/TIMP1/PLEK/TGFB2/PPBP/TOR4A/SERPINE1/HGF",12]
[103,"up","up","R-HSA-157579","Telomere Maintenance","11/428","113/10704",0.00546396052938016,0.0463385883357048,0.0386016644686979,"H2AC14/H2BC9/H2BC21/H2AC4/H2BC11/H4C15/H2BC17/H2AC19/CDK2/H2BC14/H2BC3",11]
[104,"up","up","R-HSA-69618","Mitotic Spindle Checkpoint","11/428","113/10704",0.00546396052938016,0.0463385883357048,0.0386016644686979,"UBE2C/CENPA/AURKB/KNL1/CENPM/NDC80/PLK1/KIF18A/BUB1/BIRC5/BUB1B",11]
[105,"up","up","R-HSA-168179","Toll Like Receptor TLR1:TLR2 Cascade","10/428","98/10704",5.69308563428349E-3,0.0473707691456419,0.0394615071770593,"CD14/ELK1/NFKB2/RELA/MAPKAPK3/TNIP2/MAPKAPK2/TLR2/IRAK2/MYD88",10]
[106,"up","up","R-HSA-181438","Toll Like Receptor 2 (TLR2) Cascade","10/428","98/10704",5.69308563428349E-3,0.0473707691456419,0.0394615071770593,"CD14/ELK1/NFKB2/RELA/MAPKAPK3/TNIP2/MAPKAPK2/TLR2/IRAK2/MYD88",10]
[107,"up","up","R-HSA-2173782","Binding and Uptake of Ligands by Scavenger Receptors","6/428","42/10704",0.00610266879757283,0.04995936316207,0.0416178965116659,"JCHAIN/CD163/FTL/MSR1/APOE/AMBP",6]
[108,"up","up","R-HSA-419812","Calcitonin-like ligand receptors","3/428","10/10704",0.0061741163091447,0.04995936316207,0.0416178965116659,"ADM/ADM2/RAMP1",3]
[109,"up","up","R-HSA-5602498","MyD88 deficiency (TLR2/4)","3/428","10/10704",0.0061741163091447,0.04995936316207,0.0416178965116659,"CD14/TLR2/MYD88",3]

{"sheet":"KEGG enrichments","index":3,"n_rows":56,"n_cols":12,"rows_kept":56}
[null,"Cluster","direction","ID","Description","GeneRatio","BgRatio","pvalue","p.adjust","qvalue","geneID","Count"]
[2,"up","up","hsa05322","Systemic lupus erythematosus","26/347","136/8087",8.49735449298484e-11,1.65777407968254e-08,1.27669133845521e-08,"653604/8331/85235/8968/8345/713/8349/440689/8335/714/941/8970/715/554313/2212/2214/716/717/8348/723790/721/712/6737/8342/958/3018",26]
[3,"up","up","hsa05144","Malaria","16/347","50/8087",1.21895152917834E-10,1.65777407968254e-08,1.27669133845521e-08,"3553/6401/3383/7057/3569/6347/1440/3576/6382/3683/3689/7042/7097/958/4615/3082",16]
[4,"up","up","hsa04064","NF-kappa B signaling pathway","22/347","104/8087",3.28242817337935e-10,2.7992436772644e-08,2.15576428705733e-08,"3553/10912/3383/8740/929/6351/4791/2919/597/3576/2921/7706/388372/4055/4616/7132/4049/5970/7128/8837/958/4615",22]
[5,"up","up","hsa04613","Neutrophil extracellular trap formation","30/347","190/8087",4.11653481950647e-10,2.7992436772644e-08,2.15576428705733e-08,"653604/8331/85235/8968/8345/27180/8349/440689/8335/728/51311/837/2357/8970/79792/554313/5331/2212/3683/2214/8348/5880/5970/3689/3065/723790/7097/8342/3018/2358",30]
[6,"up","up","hsa04060","Cytokine-cytokine receptor interaction","37/347","295/8087",2.91403630027417e-09,1.58523574734915e-07,1.22082783948329e-07,"3553/8793/3557/8740/4982/50615/6351/2919/6374/3569/5008/6347/1440/3576/2921/388372/3627/4055/8794/8795/7132/4049/3976/1439/6348/51330/7042/5473/3587/2660/83729/4804/9518/1435/958/943/9235",37]
[7,"up","up","hsa04061","Viral protein interaction with cytokine and cytokine receptor","20/347","100/8087",6.01201511975593e-09,2.72544685428935e-07,2.0989315944411E-7,"8793/8740/6351/2919/6374/3569/6347/3576/2921/388372/3627/4055/8794/8795/7132/4049/6348/5473/3587/1435",20]
[8,"up","up","hsa04668","TNF signaling pathway","21/347","112/8087",8.43229507925386e-09,3.2765489450815e-07,2.523348452288e-07,"3553/6401/3383/2919/6374/3569/4314/6347/2921/9021/197259/3627/4323/7132/4049/5970/7128/3976/8837/1435/1051",21]
[9,"up","up","hsa05323","Rheumatoid arthritis","18/347","93/8087",6.0071581625832e-08,2.04243377527829e-06,1.57292693993955e-06,"3553/3383/2919/6374/3569/4314/941/6347/3576/2921/3683/3689/6348/8992/7042/7097/1435/10312",18]
[10,"up","up","hsa05169","Epstein-Barr virus infection","26/347","202/8087",4.4345223038783e-07,1.34021118517211E-5,1.03212858300793e-05,"10912/3383/9636/4791/1026/3569/960/3665/7431/4609/3627/3683/4616/5970/3106/4940/7128/3065/1017/7097/3105/958/4615/3718/3134/10379",26]
[11,"up","up","hsa05133","Pertussis","15/347","76/8087",5.94281484423032e-07,1.61644563763065E-5,1.24486332000193E-5,"3553/929/713/6374/3569/714/3576/715/716/717/5970/3689/721/712/4615",15]
[12,"up","up","hsa04657","IL-17 signaling pathway","16/347","94/8087",2.01868002221224e-06,4.9916451458339e-05,3.84418492268168e-05,"3553/8061/2919/6374/3569/4314/6347/1440/3576/2921/2354/3627/10758/5970/7128/1051",16]
[13,"up","up","hsa04610","Complement and coagulation cascades","15/347","85/8087",2.64522391695722e-06,5.6353262273007e-05,4.33989906823854e-05,"5329/713/5265/728/714/715/5104/716/717/3689/11326/721/712/5054/623",15]
[14,"up","up","hsa05150","Staphylococcus aureus infection","16/347","96/8087",2.69335444687166e-06,5.6353262273007e-05,4.33989906823854e-05,"3383/713/2204/728/714/2357/715/2212/3683/2214/716/717/3689/721/712/2358",16]
[15,"up","up","hsa05134","Legionellosis","12/347","57/8087",3.97588440082094e-06,7.72457540730926e-05,5.94887966739374e-05,"3553/3304/929/4791/2919/3569/3576/2921/5970/3689/7097/4615",12]
[16,"up","up","hsa05142","Chagas disease","16/347","102/8087",6.09754848926229e-06,1.10568879271956E-4,8.51517297798734e-05,"3553/713/3569/714/6347/3576/5331/7132/5970/6348/7042/8837/712/7097/5054/4615",16]
[17,"up","up","hsa05166","Human T-cell leukemia virus 1 infection","25/347","219/8087",6.80429864265177E-6,1.13076464045647E-4,8.70828805924296E-5,"3383/6688/2002/8061/4791/1026/3569/4609/4055/3683/7132/4049/1031/5970/3106/3689/7042/1017/9133/701/3105/4772/958/3718/3134",25]
[18,"up","up","hsa05202","Transcriptional misregulation in cancer","23/347","192/8087",7.1707110714612E-6,1.13076464045647E-4,8.70828805924296E-5,"653604/10912/8968/929/6688/1026/4086/3569/597/4314/26471/3576/4609/4616/1031/5970/6692/3065/4804/5371/958/604/1051",23]
[19,"up","up","hsa04620","Toll-like receptor signaling pathway","16/347","104/8087",7.88854043229551e-06,1.13076464045647E-4,8.70828805924296E-5,"3553/929/6351/6696/3569/3665/941/51311/3576/388372/3627/5970/6348/7097/958/4615",16]
[20,"up","up","hsa04380","Osteoclast differentiation","18/347","128/8087",7.8987235914239e-06,1.13076464045647E-4,8.70828805924296E-5,"3553/4982/6688/8061/4791/2354/9021/2212/2214/7132/5970/10859/7042/126014/4772/1435/3937/10379",18]
[21,"up","up","hsa04218","Cellular senescence","20/347","156/8087",1.03709083458901E-5,1.41044353504105E-4,0.000108621618991164,"10912/4605/1026/3569/3576/4609/4616/10758/677/5970/3106/1978/7042/1017/9133/9261/5054/3105/4772/3134",20]
[22,"up","up","hsa05171","Coronavirus disease - COVID-19","25/347","232/8087",1.87138334970975e-05,0.000242260351990032,0.000186570472314304,"3553/713/9636/3569/728/714/4314/51311/6347/1440/3576/715/2212/3627/716/717/64135/7132/5970/4940/721/712/7097/4615/10379",25]
[23,"up","up","hsa05203","Viral carcinogenesis","23/347","204/8087",1.95945872933114e-05,0.000242260351990032,0.000186570472314304,"85477/8345/4791/1026/8349/440689/3665/8970/554313/4055/8348/5970/11036/3106/3065/1017/9261/3105/8342/3018/3718/3134/10379",23]
[24,"up","up","hsa04621","NOD-like receptor signaling pathway","21/347","181/8087",2.93735109576257e-05,0.000347373694803225,0.000267520763412701,"3553/2919/838/3569/3665/2634/837/6347/3576/2921/2635/79792/5331/2633/5970/4940/7128/118429/3428/4615/10379",21]
[25,"up","up","hsa05130","Pathogenic Escherichia coli infection","21/347","197/8087",1.02608592869556E-4,0.00116289738585497,0.000895574999168494,"3553/3569/837/149461/3576/2212/653857/3059/64005/81027/8795/23191/7132/5970/7430/347733/137075/4542/9075/84617/4615",21]
[26,"up","up","hsa05416","Viral myocarditis","10/347","60/8087",2.06014036967407E-4,0.00224143272220539,0.00172618077290585,"3383/4624/941/3683/5880/3106/3689/3105/958/3134",10]
[27,"up","up","hsa04115","p53 signaling pathway","11/347","73/8087",0.000252406310313068,2.64055832327517E-3,2.03355691304861E-3,"2810/10912/1026/7057/6241/9540/4616/8795/1017/9133/5054",11]
[28,"up","up","hsa04145","Phagosome","17/347","152/8087",0.000263528457427259,0.00265480520074868,0.0020445287730224,"929/7057/2204/4481/715/2212/2214/81027/3106/347733/3689/8992/7097/84617/3105/10312/3134",17]
[29,"up","up","hsa04933","AGE-RAGE signaling pathway in diabetic complications","13/347","100/8087",3.22394194430498E-4,0.00313182931732484,0.00241189641698004,"3553/6401/3383/3569/5333/6347/3576/5292/5331/5970/7042/5054/4772",13]
[30,"up","up","hsa05164","Influenza A","18/347","171/8087",0.000372602078728506,3.49475053152254E-3,0.00269139069571589,"3553/3383/3569/3665/6347/3576/7706/9021/3627/8795/64135/7132/5970/4940/5371/3337/4615/10379",18]
[31,"up","up","hsa04390","Hippo signaling pathway","17/347","157/8087",0.000387472454724931,0.00351308358950604,0.00270550942071092,"4086/84552/4609/6657/10413/7004/166824/3689/56288/25937/7042/332/5054/8994/7484/7481/2736",17]
[32,"up","up","hsa05167","Kaposi sarcoma-associated herpesvirus infection","19/347","193/8087",0.00060119883229422,0.0052750349156138,0.00406243014012053,"3383/1026/2919/3569/3665/3576/2921/4609/100507436/7132/5970/3106/4277/9261/3105/4772/3055/3134/10379",19]
[33,"up","up","hsa05152","Tuberculosis","18/347","180/8087",0.000692019651493521,0.00588216703769493,0.00452999706076351,"3553/929/3569/4046/2212/2214/7132/5970/3689/8877/7042/7421/3587/7097/3656/4615/10312/1051",18]
[34,"up","up","hsa04110","Cell cycle","14/347","124/8087",0.000825222294430657,0.0068018322450042,0.0052382531608198,"2810/10912/1026/4609/7465/4616/1031/5347/3065/7042/1017/9133/699/701",14]
[35,"up","up","hsa05146","Amoebiasis","12/347","102/8087",1.33795683124563E-3,0.010703654649965,0.00824313961046068,"3553/3315/929/2919/3569/3576/2921/5331/5970/3689/7042/7097",12]
[36,"up","up","hsa05161","Hepatitis B","16/347","162/8087",0.00154501527994778,0.0118285513010111,0.00910944933785298,"2002/1026/3569/3665/3576/4609/64135/5970/7042/1017/6554/332/7097/4772/4615/3718",16]
[37,"up","up","hsa05163","Human cytomegalovirus infection","20/347","225/8087",1.56554355454559E-3,0.0118285513010111,0.00910944933785298,"3553/6351/2002/1026/3569/6347/3576/388372/4609/5331/7132/5880/5970/3106/1978/6348/3587/3105/4772/3134",20]
[38,"up","up","hsa04514","Cell adhesion molecules","15/347","149/8087",0.00177603457859603,0.0130562541994087,0.0100549326071297,"6401/3383/6614/941/149461/6382/3683/3106/3689/137075/9075/3105/958/5819/3134",15]
[39,"up","up","hsa05132","Salmonella infection","21/347","249/8087",0.00231092934702099,0.0165413890102555,0.012738918007124,"3553/929/838/3569/837/3576/4609/79792/197259/653857/81027/8795/23191/7132/26084/5970/347733/7097/84617/29109/4615",21]
[40,"up","up","hsa05162","Measles","14/347","139/8087",0.00248882541243891,0.017357961850856,0.013367780217958,"3553/3304/3569/3665/64135/5970/4940/7128/4478/1017/7097/4615/3718/10379",14]
[41,"up","up","hsa04650","Natural killer cell mediated cytotoxicity","13/347","131/8087",0.00398805821008117,0.0265365470589109,0.0204364274950591,"3383/100507436/3683/2214/8795/5880/3106/4277/3689/3105/4772/10870/3937",13]
[42,"up","up","hsa04630","JAK-STAT signaling pathway","15/347","162/8087",0.00399999422579172,0.0265365470589109,0.0204364274950591,"50615/1026/3569/5008/1440/5292/9021/4609/1154/3976/1439/3587/3718/2670/10379",15]
[43,"up","up","hsa05143","African trypanosomiasis","6/347","37/8087",0.00449928654292628,0.0291382366589511,0.0224400506777526,"3553/6401/3383/3569/5331/4615",6]
[44,"up","up","hsa05140","Leishmaniasis","9/347","77/8087",0.00545567087086384,0.0345102901598829,0.0265771971432535,"3553/2002/2212/2214/5970/3689/7042/7097/4615",9]
[45,"up","up","hsa05034","Alcoholism","16/347","187/8087",0.00646815000839542,0.0399849273246262,0.0307933457337485,"653604/8331/85235/8968/8345/8349/440689/8335/2354/8970/554313/8348/3065/723790/8342/3018",16]
[46,"up","up","hsa05205","Proteoglycans in cancer","17/347","205/8087",0.00691806008162961,0.041815829826739,0.0322033673975273,"5329/2002/1026/7057/960/6608/6382/4609/3059/7430/4478/7042/2064/7097/3082/7484/7481",17]
[47,"up","up","hsa04392","Hippo signaling pathway - multiple species","5/347","29/8087",0.00717002295164851,0.0420768693800079,0.0324044001804241,"10413/7004/166824/25937/8994",5]
[48,"up","up","hsa05160","Hepatitis C","14/347","157/8087",0.00741468986774691,0.0420768693800079,0.0324044001804241,"1026/3665/149461/9021/4609/3627/7132/5970/4940/137075/8837/1017/9075/10379",14]
[49,"up","up","hsa05219","Bladder cancer","6/347","41/8087",0.00753813754094037,0.0420768693800079,0.0324044001804241,"1026/7057/3576/4609/2064/1890",6]
[50,"up","up","hsa05221","Acute myeloid leukemia","8/347","67/8087",0.00758002426331025,0.0420768693800079,0.0324044001804241,"929/6688/597/5292/4609/5970/1978/5371",8]
[51,"up","up","hsa04217","Necroptosis","14/347","159/8087",0.00826146007816594,0.0435461597111237,0.0335359356908422,"3553/8331/85235/8335/2512/197259/8795/7132/7128/5836/723790/8837/3718/10379",14]
[52,"up","up","hsa04062","Chemokine signaling pathway","16/347","192/8087",0.00827637134606164,0.0435461597111237,0.0335359356908422,"6351/2919/6374/6347/3576/2921/388372/5331/3627/5880/5970/56288/6348/5473/3718/3055",16]
[53,"up","up","hsa04666","Fc gamma R-mediated phagocytosis","10/347","97/8087",0.0084621999402004,0.0435461597111237,0.0335359356908422,"85477/55616/3985/7408/2212/653857/2214/5880/8877/3055",10]
[54,"up","up","hsa05332","Graft-versus-host disease","6/347","42/8087",0.00848509729665278,0.0435461597111237,0.0335359356908422,"3553/3569/941/3106/3105/3134",6]
[55,"up","up","hsa04940","Type I diabetes mellitus","6/347","43/8087",9.51446210016124E-3,0.0479246979859973,0.036907952396337,"3553/941/4049/3106/3105/3134",6]
[1,"down","down","hsa04360","Axon guidance",43556,"182/8087",0.000738212655222135,0.043554546658106,0.0435156933604627,"8482/5781/84448/59277",4]

{"sheet":"GO enrichments","index":4,"n_rows":755,"n_cols":12,"rows_kept":755}
[null,"Cluster","direction","ID","Description","GeneRatio","BgRatio","pvalue","p.adjust","qvalue","geneID","Count"]
[1,"up","up","GO:0032496","response to lipopolysaccharide","48/604","334/18866",{"v":1.93200672768578e-18,"d":"1.93E-18"},{"v":9.36443660909297e-15,"d":"9.36E-15"},{"v":7.08741415366836E-15,"d":"7.09E-15"},"IL1B/SELE/CD180/ICAM1/CD14/NFKB2/CXCL1/CXCL5/IL6/C5AR1/CD80/CCL2/CSF3/CXCL8/CXCL3/ABCA1/LGALS9/VIM/HAMP/CXCL10/LTF/LTA/CD68/IRGM/RELA/LILRB1/TNFAIP3/TRIM5/MAPKAPK3/ADM/CSF2RB/SBNO2/SLC11A1/CCL3/TNIP2/MGST1/PPBP/MAPKAPK2/IL10RA/TLR2/IRAK2/SERPINE1/CD40/BDKRB1/MYD88/GHSR/HCK/CEBPB",48]
[2,"up","up","GO:0002237","response to molecule of bacterial origin","49/604","356/18866",{"v":5.2315481301547e-18,"d":"5.23E-18"},{"v":1.26786568934299e-14,"d":"1.27E-14"},{"v":9.59576064925744e-15,"d":"9.60E-15"},"IL1B/SELE/CD180/ICAM1/CD14/NFKB2/CXCL1/CXCL5/IL6/C5AR1/CD80/CCL2/CSF3/CXCL8/CXCL3/ABCA1/LGALS9/VIM/HAMP/CXCL10/LTF/LTA/CD68/IRGM/RELA/LILRB1/TNFAIP3/TRIM5/MAPKAPK3/ADM/CSF2RB/SBNO2/SLC11A1/CCL3/TNIP2/MGST1/C4B/PPBP/MAPKAPK2/IL10RA/TLR2/IRAK2/SERPINE1/CD40/BDKRB1/MYD88/GHSR/HCK/CEBPB",49]
[3,"up","up","GO:0034341","response to interferon-gamma","36/604","202/18866",{"v":3.74306210517485e-17,"d":"3.74E-17"},{"v":6.04754067459417e-14,"d":"6.05E-14"},{"v":4.5770426093103e-14,"d":"4.58E-14"},"ICAM1/FCGR1B/CCL4/BST2/CD44/IRF7/GBP2/CCL2/IFI30/LGALS9/GBP3/TRIM25/CCL4L1/SOCS3/VIM/MID1/GBP1/IRGM/NMI/HLA-B/OAS3/TRIM5/SLC11A1/CCL3/IFITM3/TLR2/MT2A/TRIM21/PML/HLA-A/OASL/CD40/PARP9/HCK/HLA-F/IRF9",36]
[4,"up","up","GO:0071222","cellular response to lipopolysaccharide","35/604","208/18866",{"v":6.61215952122245e-16,"d":"6.61E-16"},{"v":6.66591990778845e-13,"d":"6.67E-13"},{"v":5.04505899007368e-13,"d":"5.05E-13"},"IL1B/CD180/ICAM1/CD14/CXCL1/CXCL5/IL6/CD80/CCL2/CSF3/CXCL8/CXCL3/ABCA1/VIM/HAMP/CXCL10/LTF/CD68/IRGM/RELA/LILRB1/TNFAIP3/TRIM5/SBNO2/CCL3/TNIP2/PPBP/TLR2/IRAK2/SERPINE1/CD40/MYD88/GHSR/HCK/CEBPB",35]
[5,"up","up","GO:0060333","interferon-gamma-mediated signaling pathway","24/604","91/18866",{"v":6.87633578274031e-16,"d":"6.88E-16"},{"v":6.66591990778845e-13,"d":"6.67E-13"},{"v":5.04505899007368e-13,"d":"5.05E-13"},"ICAM1/FCGR1B/CD44/IRF7/GBP2/IFI30/TRIM25/SOCS3/MID1/GBP1/IRGM/NMI/HLA-B/OAS3/TRIM5/MT2A/TRIM21/PML/HLA-A/OASL/PARP9/HCK/HLA-F/IRF9",24]
[6,"up","up","GO:0071346","cellular response to interferon-gamma","32/604","182/18866",{"v":3.2591138783329e-15,"d":"3.26E-15"},{"v":2.6328208280466e-12,"d":"2.63E-12"},{"v":1.99263366070003e-12,"d":"1.99E-12"},"ICAM1/FCGR1B/CCL4/CD44/IRF7/GBP2/CCL2/IFI30/LGALS9/GBP3/TRIM25/CCL4L1/SOCS3/VIM/MID1/GBP1/IRGM/NMI/HLA-B/OAS3/TRIM5/CCL3/TLR2/MT2A/TRIM21/PML/HLA-A/OASL/PARP9/HCK/HLA-F/IRF9",32]
[7,"up","up","GO:0071219","cellular response to molecule of bacterial origin","35/604","222/18866",{"v":5.2033823977105e-15,"d":"5.20E-15"},{"v":3.60297064024326E-12,"d":"3.60E-12"},{"v":2.72688536180768e-12,"d":"2.73E-12"},"IL1B/CD180/ICAM1/CD14/CXCL1/CXCL5/IL6/CD80/CCL2/CSF3/CXCL8/CXCL3/ABCA1/VIM/HAMP/CXCL10/LTF/CD68/IRGM/RELA/LILRB1/TNFAIP3/TRIM5/SBNO2/CCL3/TNIP2/PPBP/TLR2/IRAK2/SERPINE1/CD40/MYD88/GHSR/HCK/CEBPB",35]
[8,"up","up","GO:0071216","cellular response to biotic stimulus","35/604","246/18866",{"v":1.23183140833249e-13,"d":"1.23E-13"},{"v":7.46335854523449e-11,"d":"7.46E-11"},{"v":5.64859533952466e-11,"d":"5.65E-11"},"IL1B/CD180/ICAM1/CD14/CXCL1/CXCL5/IL6/CD80/CCL2/CSF3/CXCL8/CXCL3/ABCA1/VIM/HAMP/CXCL10/LTF/CD68/IRGM/RELA/LILRB1/TNFAIP3/TRIM5/SBNO2/CCL3/TNIP2/PPBP/TLR2/IRAK2/SERPINE1/CD40/MYD88/GHSR/HCK/CEBPB",35]
[9,"up","up","GO:0043312","neutrophil degranulation","50/604","487/18866",{"v":3.51330822896812e-13,"d":"3.51E-13"},{"v":1.89211166508983E-10,"d":"1.89E-10"},{"v":1.43203265239227e-10,"d":"1.43E-10"},"PLAUR/HSPA1B/CD14/CHI3L1/CXCL1/SERPINA1/SIGLEC9/BST2/CD44/FCAR/C5AR1/FTL/LRG1/FPR1/ORM2/GSDMD/HEBP2/FCGR2A/LGALS3/LTF/SERPINA3/ITGAL/S100A11/CYFIP1/HK3/HVCN1/CD68/HLA-B/GPR84/PYGL/ITGB2/SLC11A1/PNP/MGST1/OSCAR/RNASE2/NBEAL2/PPBP/TLR2/SIGLEC14/NFAM1/DOK3/PLEKHO2/CD300A/VNN1/FABP5/TCIRG1/FPR2/ABCA13/CLEC5A",50]
[10,"up","up","GO:0002283","neutrophil activation involved in immune response","50/604","490/18866",{"v":4.44075960513702e-13,"d":"4.44E-13"},{"v":2.15243618060991E-10,"d":"2.15E-10"},{"v":1.62905760251605e-10,"d":"1.63E-10"},"PLAUR/HSPA1B/CD14/CHI3L1/CXCL1/SERPINA1/SIGLEC9/BST2/CD44/FCAR/C5AR1/FTL/LRG1/FPR1/ORM2/GSDMD/HEBP2/FCGR2A/LGALS3/LTF/SERPINA3/ITGAL/S100A11/CYFIP1/HK3/HVCN1/CD68/HLA-B/GPR84/PYGL/ITGB2/SLC11A1/PNP/MGST1/OSCAR/RNASE2/NBEAL2/PPBP/TLR2/SIGLEC14/NFAM1/DOK3/PLEKHO2/CD300A/VNN1/FABP5/TCIRG1/FPR2/ABCA13/CLEC5A",50]
[11,"up","up","GO:0002683","negative regulation of immune system process","45/604","463/18866",{"v":3.59083373960541e-11,"d":"3.59E-11"},{"v":1.58225192144249e-08,"d":"1.58E-08"},{"v":1.19751728062439E-8,"d":"1.20E-08"},"FOXJ1/CYP19A1/MDK/HMOX1/THBS1/BST2/C1QC/TMEM176A/CD80/CCL2/LGALS9/SOX9/MYC/H4C15/MICA/LGALS3/LTF/TMEM176B/ZFP36L1/GBP1/CD68/LILRB1/NMI/HLA-B/TNFAIP3/EMILIN1/EZR/MICB/VSIG4/CCL3/IFI16/TGFB2/ERBB2/BLK/HLA-A/AMBP/HLX/ITPKB/CD300A/FGL1/BCL6/JAK3/CEBPB/HLA-F/ADA",45]
[12,"up","up","GO:0051607","defense response to virus","32/604","258/18866",{"v":5.75380879157979e-11,"d":"5.75E-11"},{"v":2.32405926773227e-08,"d":"2.32E-08"},{"v":1.75894944198733E-8,"d":"1.76E-08"},"IL1B/IFI6/ISG15/IL6/ZC3HAV1/BST2/IRF7/TLR8/GBP3/MLKL/MICA/CXCL10/TRAF3IP2/IFIH1/GBP1/RELA/LILRB1/OAS3/TNFAIP3/TRIM5/MICB/IFI16/PLSCR1/RNASE2/IFITM3/PML/HERC5/OASL/CD40/DTX3L/PARP9/IRF9",32]
[13,"up","up","GO:0009615","response to virus","37/604","349/18866",{"v":1.8277976120604e-10,"d":"1.83E-10"},{"v":6.81487309665906e-08,"d":"6.81E-08"},{"v":5.15779326156316e-08,"d":"5.16E-08"},"IL1B/IFI6/HSPB1/CCL4/FOSL1/ISG15/IL6/ZC3HAV1/BST2/IRF7/TLR8/LGALS9/GBP3/MLKL/MICA/CXCL10/TRAF3IP2/IFIH1/GBP1/IRGM/RELA/LILRB1/OAS3/TNFAIP3/TRIM5/MICB/IFI16/PLSCR1/RNASE2/IFITM3/PML/HERC5/OASL/CD40/DTX3L/PARP9/IRF9",37]
[14,"up","up","GO:0002685","regulation of leukocyte migration","28/604","212/18866",{"v":2.13268417403342e-10,"d":"2.13E-10"},{"v":7.38365727967143e-08,"d":"7.38E-08"},{"v":5.58827394474171e-08,"d":"5.59E-08"},"SELE/ICAM1/TNFSF14/CCL4/CYP19A1/MDK/HMOX1/THBS1/IL6/C5AR1/CCL2/CXCL8/LGALS9/CXCL10/LGALS3/MMP14/RAC2/EMILIN1/CCL3/MSN/MSTN/SERPINE1/SLC8B1/CSF1/CD300A/BDKRB1/FPR2/ADA",28]
[15,"up","up","GO:0030595","leukocyte chemotaxis","29/604","232/18866",{"v":3.83339646761453E-10,"d":"3.83E-10"},{"v":1.19040816340517e-07,"d":"1.19E-07"},{"v":9.00952830175372e-08,"d":"9.01E-08"},"IL1B/TNFSF14/CCL4/CYP19A1/MDK/CXCL1/CXCL5/HSD3B7/THBS1/IL6/C5AR1/CCL2/CXCL8/CXCL3/LGALS9/CCL4L1/ARHGEF5/CXCL10/LGALS3/RAC2/ITGB2/CCL3/TGFB2/PPBP/MSTN/SERPINE1/SLC8B1/CSF1/FPR2",29]
[16,"up","up","GO:1903706","regulation of hemopoiesis","45/604","498/18866",{"v":3.92955036403606e-10,"d":"3.93E-10"},{"v":1.19040816340517e-07,"d":"1.19E-07"},{"v":9.00952830175372e-08,"d":"9.01E-08"},"IL1B/FOXJ1/H3C13/HSPA1B/SCIN/H3C7/SPI1/MDK/ISG15/THBS1/IRF7/C1QC/TMEM176A/CD80/OSM/CSF3/LGALS9/PIM1/MYC/H4C15/LGALS3/LTF/MMP14/HCLS1/TMEM176B/ZFP36L1/YAP1/LILRB1/HLA-B/LIF/CCL3/PNP/HDAC1/ERBB2/NFAM1/NOTCH2/HLX/CSF1/ITPKB/VNN1/BCL6/JAK3/GLI2/CEBPB/ADA",45]
[17,"up","up","GO:0030099","myeloid cell differentiation","41/604","431/18866",{"v":5.26995691904155e-10,"d":"5.27E-10"},{"v":1.50255771685849e-07,"d":"1.50E-07"},{"v":1.13720122989844e-07,"d":"1.14E-07"},"H3C13/HSPA1B/SCIN/H3C7/SPI1/ISG15/THBS1/BATF/IRF7/C1QC/CSF3/SLC4A1/MYC/H4C15/LTBR/LGALS3/LTF/HCLS1/ALAS2/ZFP36L1/LILRB1/LIF/SBNO2/PIR/CCL3/IFI16/HDAC1/ETV2/OSCAR/NBEAL2/DYRK3/TLR2/PML/NOTCH2/CSF1/ITPKB/BCL6/TCIRG1/JAK3/CEBPB/CLEC5A",41]
[18,"up","up","GO:0097529","myeloid leukocyte migration","28/604","222/18866",{"v":6.26961210089377e-10,"d":"6.27E-10"},{"v":1.68826721405734E-7,"d":"1.69E-07"},{"v":1.2777542790418e-07,"d":"1.28E-07"},"IL1B/CCL4/CYP19A1/MDK/CXCL1/CXCL5/THBS1/IL6/C5AR1/CCL2/CXCL8/CXCL3/CCL4L1/ARHGEF5/CXCL10/LGALS3/MMP14/RAC2/EMILIN1/ITGB2/CCL3/TGFB2/PPBP/MSTN/SERPINE1/CSF1/CD300A/FPR2",28]
[19,"up","up","GO:0002697","regulation of immune effector process","42/604","470/18866",{"v":2.15099574930723E-9,"d":"2.15E-09"},{"v":5.48730336678535e-07,"d":"5.49E-07"},{"v":4.15303057414721e-07,"d":"4.15E-07"},"IL1B/FOXJ1/ICAM1/C1QB/HMOX1/IL6/BST2/C5AR1/C1QC/CD80/MR1/LGALS9/C1R/MICA/LGALS3/C1S/C2/TRAF3IP2/LTA/RAC2/LILRB1/HLA-B/TNFAIP3/MICB/ITGB2/VSIG4/C4B/TGFB2/C1QA/BLK/HLA-A/HERC5/HLX/CD40/CD300A/MZB1/DTX3L/PARP9/BCL6/NECTIN2/JAK3/HLA-F",42]
[20,"up","up","GO:0002460","adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains","36/604","370/18866",{"v":3.36229214708644e-09,"d":"3.36E-09"},{"v":8.14851501846398e-07,"d":"8.15E-07"},{"v":6.16715164873486e-07,"d":"6.17E-07"},"IL1B/FOXJ1/ICAM1/C1QB/NFKB2/BATF/IL6/IRF7/C1QC/CD80/TLR8/MR1/C1R/BTN3A2/MICA/C1S/MYO1G/C2/LTA/LILRB1/HLA-B/TNFAIP3/SLC11A1/C4B/C1QA/BTN3A3/HLA-A/HLX/CD40/BCL6/TCIRG1/NECTIN2/JAK3/KLHL6/HLA-F/ADA",36]
[21,"up","up","GO:0071621","granulocyte chemotaxis","20/604","127/18866",{"v":3.86742736889428e-09,"d":"3.87E-09"},{"v":8.60687698999898e-07,"d":"8.61E-07"},{"v":6.51405998504695e-07,"d":"6.51E-07"},"IL1B/CCL4/MDK/CXCL1/CXCL5/THBS1/C5AR1/CCL2/CXCL8/CXCL3/CCL4L1/CXCL10/LGALS3/RAC2/ITGB2/CCL3/TGFB2/PPBP/MSTN/CSF1",20]
[22,"up","up","GO:0048608","reproductive structure development","40/604","443/18866",{"v":3.90656682030075E-9,"d":"3.91E-09"},{"v":8.60687698999898e-07,"d":"8.61E-07"},{"v":6.51405998504695e-07,"d":"6.51E-07"},"RAB13/ICAM1/CYP19A1/SPP1/FOSL1/AKR1C3/PLCD1/NUPR1/SOX9/SOCS3/SDC1/SNAI1/ST14/NRK/SERPINA5/MMP14/E2F7/ZFP36L1/LIF/ADM/LHCGR/SPINT1/MGST1/TGFB2/KIF18A/ETV2/VDR/STC1/FST/MMP19/NOTCH2/TEX19/FANCG/ASCL2/GHSR/WNT9B/GLI2/CEBPB/CCN1/ADA",40]
[23,"up","up","GO:1902105","regulation of leukocyte differentiation","31/604","290/18866",{"v":4.59120217365134e-09,"d":"4.59E-09"},{"v":9.67545953725566e-07,"d":"9.68E-07"},{"v":7.32280987422192e-07,"d":"7.32E-07"},"IL1B/FOXJ1/MDK/IRF7/C1QC/TMEM176A/CD80/LGALS9/MYC/LTF/MMP14/HCLS1/TMEM176B/ZFP36L1/LILRB1/HLA-B/LIF/CCL3/PNP/ERBB2/NFAM1/NOTCH2/HLX/CSF1/ITPKB/VNN1/BCL6/JAK3/GLI2/CEBPB/ADA",31]
[24,"up","up","GO:0061458","reproductive system development","40/604","447/18866",{"v":5.0481270961127e-09,"d":"5.05E-09"},{"v":1.01951133478576E-6,"d":"1.02E-06"},{"v":7.7161065482249e-07,"d":"7.72E-07"},"RAB13/ICAM1/CYP19A1/SPP1/FOSL1/AKR1C3/PLCD1/NUPR1/SOX9/SOCS3/SDC1/SNAI1/ST14/NRK/SERPINA5/MMP14/E2F7/ZFP36L1/LIF/ADM/LHCGR/SPINT1/MGST1/TGFB2/KIF18A/ETV2/VDR/STC1/FST/MMP19/NOTCH2/TEX19/FANCG/ASCL2/GHSR/WNT9B/GLI2/CEBPB/CCN1/ADA",40]
[25,"up","up","GO:0001890","placenta development","22/604","156/18866",{"v":5.42899024002369e-09,"d":"5.43E-09"},{"v":1.05257262773579E-6,"d":"1.05E-06"},{"v":7.9663288364137e-07,"d":"7.97E-07"},"SPP1/FOSL1/PLCD1/SOCS3/SNAI1/ST14/NRK/E2F7/ZFP36L1/LIF/ADM/SPINT1/ETV2/VDR/STC1/NOTCH2/TEX19/ASCL2/GHSR/CEBPB/CCN1/ADA",22]
[26,"up","up","GO:0060326","cell chemotaxis","32/604","311/18866",{"v":6.5999244392503e-09,"d":"6.60E-09"},{"v":1.23037822142485e-06,"d":"1.23E-06"},{"v":9.31203913797057e-07,"d":"9.31E-07"},"IL1B/RAB13/HSPB1/TNFSF14/CCL4/CYP19A1/MDK/CXCL1/CXCL5/HSD3B7/THBS1/IL6/C5AR1/CCL2/CXCL8/CXCL3/LGALS9/CCL4L1/ARHGEF5/CXCL10/LGALS3/RAC2/ITGB2/CCL3/TGFB2/PPBP/MSTN/SERPINE1/SLC8B1/CSF1/FPR2/HGF",32]
[27,"up","up","GO:0007159","leukocyte cell-cell adhesion","35/604","364/18866",{"v":7.57205916230176e-09,"d":"7.57E-09"},{"v":1.35932484295099e-06,"d":"1.36E-06"},{"v":1.02879634232443E-6,"d":"1.03E-06"},"IL1B/FOXJ1/SELE/ICAM1/TNFSF14/MDK/IL6/CD44/FERMT3/CD80/CCL2/LGALS9/LGALS3/ITGAL/RAC2/RELA/LILRB1/EZR/ITGB2/VSIG4/PNP/MSN/SPTA1/ERBB2/HLA-A/HLX/ITPKB/CD300A/VNN1/FGL1/BCL6/JAK3/GLI2/CEBPB/ADA",35]
[28,"up","up","GO:0097530","granulocyte migration","21/604","150/18866",{"v":1.37808112087866e-08,"d":"1.38E-08"},{"v":2.38555685460675e-06,"d":"2.39E-06"},{"v":1.80549349859479E-6,"d":"1.81E-06"},"IL1B/CCL4/MDK/CXCL1/CXCL5/THBS1/C5AR1/CCL2/CXCL8/CXCL3/CCL4L1/CXCL10/LGALS3/RAC2/ITGB2/CCL3/TGFB2/PPBP/MSTN/CSF1/CD300A",21]
[29,"up","up","GO:0002687","positive regulation of leukocyte migration","20/604","142/18866",{"v":2.74645328270266e-08,"d":"2.75E-08"},{"v":4.352113292638e-06,"d":"4.35E-06"},{"v":3.29386920283701e-06,"d":"3.29E-06"},"SELE/ICAM1/TNFSF14/CCL4/MDK/THBS1/IL6/C5AR1/CXCL8/LGALS9/CXCL10/LGALS3/MMP14/RAC2/CCL3/MSTN/SERPINE1/CSF1/BDKRB1/FPR2",20]
[30,"up","up","GO:0030593","neutrophil chemotaxis","17/604","103/18866",{"v":2.77604708533103e-08,"d":"2.78E-08"},{"v":4.352113292638e-06,"d":"4.35E-06"},{"v":3.29386920283701e-06,"d":"3.29E-06"},"IL1B/CCL4/MDK/CXCL1/CXCL5/C5AR1/CCL2/CXCL8/CXCL3/CCL4L1/CXCL10/LGALS3/RAC2/ITGB2/CCL3/TGFB2/PPBP",17]
[31,"up","up","GO:0070661","leukocyte proliferation","31/604","313/18866",{"v":2.78348487872453e-08,"d":"2.78E-08"},{"v":4.352113292638e-06,"d":"4.35E-06"},{"v":3.29386920283701e-06,"d":"3.29E-06"},"IL1B/FOXJ1/CD180/TNFSF14/CDKN1A/IL6/BST2/CD80/BTN3A1/LGALS9/LGALS3/RAC2/LILRB1/TNFAIP3/VSIG4/SLC11A1/PNP/MSN/SPTA1/ERBB2/BLK/HLA-A/CSF1/CD40/CD300A/MZB1/BCL6/TCIRG1/JAK3/CEBPB/ADA",31]
[32,"up","up","GO:0048525","negative regulation of viral process","17/604","104/18866",{"v":3.22137157493226E-8,"d":"3.22E-08"},{"v":4.87937125740521E-6,"d":"4.88E-06"},{"v":3.69292103244702e-06,"d":"3.69E-06"},"CCL4/ISG15/ZC3HAV1/BST2/TRIM25/LTF/OAS3/TRIM5/CCL3/IFI16/PLSCR1/HDAC1/IFITM3/TRIM21/PML/OASL/TRIM14",17]
[33,"up","up","GO:0007249","I-kappaB kinase/NF-kappaB signaling","29/604","286/18866",{"v":4.6826444792161e-08,"d":"4.68E-08"},{"v":6.87781145174558e-06,"d":"6.88E-06"},{"v":5.20542775440769e-06,"d":"5.21E-06"},"IL1B/HSPB1/CD14/HMOX1/BST2/NEK6/TLR8/ALPK1/LGALS9/TRIM25/LTBR/LTF/TRAF3IP2/SECTM1/TNFRSF10B/TNFRSF1A/RELA/TNFAIP3/TRIM5/TNIP2/HDAC1/RHOC/CFLAR/TLR2/IRAK2/TRIM21/CD40/TRIM14/MYD88",29]
[34,"up","up","GO:0042063","gliogenesis","30/604","307/18866",{"v":6.3038902219334e-08,"d":"6.30E-08"},{"v":8.98675173697388e-06,"d":"8.99E-06"},{"v":6.80156576577024e-06,"d":"6.80E-06"},"IL1B/BACE2/MDK/IL6/C5AR1/SMO/CCL2/SOX9/VIM/SOX2/MMP14/PITX3/NR2E1/LTA/CDKN2C/RELA/LIF/PARD3/CCL3/SPINT1/HDAC1/TGFB2/C1QA/ERBB2/TLR2/KLF15/CSF1/LGI4/FPR2/ASCL2",30]
[35,"up","up","GO:0002704","negative regulation of leukocyte mediated immunity","12/604","52/18866",{"v":6.65520650951845e-08,"d":"6.66E-08"},{"v":9.21651027189597e-06,"d":"9.22E-06"},{"v":6.97545704832234e-06,"d":"6.98E-06"},"FOXJ1/HMOX1/BST2/LGALS9/MICA/LILRB1/HLA-B/HLA-A/CD300A/BCL6/JAK3/HLA-F",12]
[36,"up","up","GO:0002688","regulation of leukocyte chemotaxis","18/604","124/18866",{"v":8.47184497248839e-08,"d":"8.47E-08"},{"v":1.14063979393476E-5,"d":"1.14E-05"},{"v":8.63285956991872E-6,"d":"8.63E-06"},"TNFSF14/CCL4/CYP19A1/MDK/THBS1/IL6/C5AR1/CCL2/CXCL8/LGALS9/CXCL10/RAC2/CCL3/MSTN/SERPINE1/SLC8B1/CSF1/FPR2",18]
[37,"up","up","GO:0097028","dendritic cell differentiation","11/604","44/18866",{"v":9.70657138785981e-08,"d":"9.71E-08"},{"v":1.27156085180964E-5,"d":"1.27E-05"},{"v":9.62372725083682e-06,"d":"9.62E-06"},"SPI1/BATF/TMEM176A/LGALS9/LTBR/TMEM176B/LILRB1/HLA-B/BLK/NOTCH2/CEBPB",11]
[38,"up","up","GO:0042110","T cell activation","39/604","483/18866",{"v":1.25734761642204e-07,"d":"1.26E-07"},{"v":1.60377997284149e-05,"d":"1.60E-05"},{"v":1.21381064909441e-05,"d":"1.21E-05"},"IL1B/FOXJ1/ICAM1/TNFSF14/MDK/BATF/IL6/CD44/CD80/BTN3A1/CCL2/MR1/LGALS9/MICA/LGALS3/ITGAL/ZFP36L1/RAC2/LILRB1/MICB/VSIG4/SLC11A1/PNP/MSN/SPTA1/ERBB2/HLA-A/LCP1/HLX/ITPKB/CD300A/VNN1/FGL1/BCL6/TCIRG1/JAK3/GLI2/CEBPB/ADA",39]
[39,"up","up","GO:0150076","neuroinflammatory response","14/604","77/18866",{"v":1.33893501922215e-07,"d":"1.34E-07"},{"v":1.66405590722301E-5,"d":"1.66E-05"},{"v":1.25943010580005E-5,"d":"1.26E-05"},"IL1B/BACE2/IL6/C5AR1/MMP3/SMO/TLR8/NUPR1/ITGB2/CCL3/SPHK1/C1QA/TLR2/FPR2",14]
[40,"up","up","GO:0030856","regulation of epithelial cell differentiation","21/604","171/18866",{"v":1.39199149109993e-07,"d":"1.39E-07"},{"v":1.68674568934035e-05,"d":"1.69E-05"},{"v":1.27660272275876E-5,"d":"1.28E-05"},"SFN/IL1B/FOXJ1/KDF1/SMO/MAFF/PLAAT4/SOX9/MYCL/ZFP36L1/YAP1/TNFRSF1A/LIF/WWTR1/ETV2/VDR/SERPINE1/WNT9B/TMEM100/BTG1/CEBPB",21]
[41,"up","up","GO:0034612","response to tumor necrosis factor","30/604","320/18866",{"v":1.5748716742651E-7,"d":"1.57E-07"},{"v":1.86180561101535e-05,"d":"1.86E-05"},{"v":1.40909570855298e-05,"d":"1.41E-05"},"SELE/HSPA1B/ICAM1/TNFSF14/CD14/TNFRSF11B/CCL4/CHI3L1/THBS1/GBP2/CASP4/CCL2/CXCL8/GBP3/CCL4L1/H2BC11/HAMP/LTBR/ZFP36L1/GBP1/TNFRSF1A/LTA/RELA/TNFAIP3/CCL3/TNFRSF12A/SLC2A4/SPHK1/CD40/TNFRSF8",30]
[42,"up","up","GO:0043123","positive regulation of I-kappaB kinase/NF-kappaB signaling","22/604","188/18866",{"v":1.66569886323585e-07,"d":"1.67E-07"},{"v":1.88187049610606e-05,"d":"1.88E-05"},{"v":1.42428168892959e-05,"d":"1.42E-05"},"IL1B/HMOX1/BST2/NEK6/ALPK1/LGALS9/TRIM25/LTBR/LTF/TRAF3IP2/SECTM1/TNFRSF10B/TNFRSF1A/RELA/TRIM5/TNIP2/RHOC/CFLAR/TRIM21/CD40/TRIM14/MYD88",22]
[43,"up","up","GO:0032943","mononuclear cell proliferation","28/604","286/18866",{"v":1.66949517913267E-7,"d":"1.67E-07"},{"v":1.88187049610606e-05,"d":"1.88E-05"},{"v":1.42428168892959e-05,"d":"1.42E-05"},"IL1B/FOXJ1/CD180/TNFSF14/CDKN1A/IL6/CD80/BTN3A1/LGALS9/LGALS3/RAC2/LILRB1/VSIG4/SLC11A1/PNP/MSN/SPTA1/ERBB2/BLK/HLA-A/CSF1/CD40/CD300A/MZB1/BCL6/JAK3/CEBPB/ADA",28]
[44,"up","up","GO:0050777","negative regulation of immune response","20/604","159/18866",{"v":1.85711599308506e-07,"d":"1.86E-07"},{"v":2.04578209510984e-05,"d":"2.05E-05"},{"v":1.54833713777546e-05,"d":"1.55E-05"},"FOXJ1/HMOX1/BST2/LGALS9/MICA/LGALS3/LILRB1/NMI/HLA-B/TNFAIP3/VSIG4/IFI16/TGFB2/HLA-A/AMBP/HLX/CD300A/BCL6/JAK3/HLA-F",20]
[45,"up","up","GO:0070663","regulation of leukocyte proliferation","25/604","240/18866",{"v":2.36934461186259E-7,"d":"2.37E-07"},{"v":2.55204740748844E-5,"d":"2.55E-05"},{"v":1.93150081224354E-5,"d":"1.93E-05"},"IL1B/FOXJ1/CDKN1A/IL6/BST2/CD80/LGALS9/LGALS3/RAC2/LILRB1/TNFAIP3/VSIG4/PNP/SPTA1/ERBB2/BLK/HLA-A/CSF1/CD40/CD300A/MZB1/BCL6/JAK3/CEBPB/ADA",25]
[46,"up","up","GO:0051384","response to glucocorticoid","19/604","147/18866",{"v":2.44117728528272e-07,"d":"2.44E-07"},{"v":2.57225789168812e-05,"d":"2.57E-05"},{"v":1.94679698837764e-05,"d":"1.95E-05"},"NPAS4/IL1RN/ICAM1/MDK/FOSL1/CDKN1A/HSD11B2/IL6/FAM107A/FOSB/SDC1/ZFP36L1/AGXT/EIF4EBP1/ADM/CFLAR/STC1/MSTN/GHSR",19]
[47,"up","up","GO:1904035","regulation of epithelial cell apoptotic process","15/604","94/18866",{"v":2.87151476408789e-07,"d":"2.87E-07"},{"v":2.90261394232817E-5,"d":"2.90E-05"},{"v":2.19682485943854E-5,"d":"2.20E-05"},"ICAM1/MDK/HMOX1/THBS1/IL6/AKR1C3/CCL2/NUPR1/ZFP36L1/YAP1/TNFAIP3/TNIP2/CFLAR/SERPINE1/CD40",15]
[48,"up","up","GO:1903037","regulation of leukocyte cell-cell adhesion","30/604","329/18866",{"v":2.8744681087632e-07,"d":"2.87E-07"},{"v":2.90261394232817E-5,"d":"2.90E-05"},{"v":2.19682485943854E-5,"d":"2.20E-05"},"IL1B/FOXJ1/SELE/ICAM1/TNFSF14/MDK/IL6/CD44/CD80/CCL2/LGALS9/LGALS3/RELA/LILRB1/ITGB2/VSIG4/PNP/SPTA1/ERBB2/HLA-A/HLX/ITPKB/CD300A/VNN1/FGL1/BCL6/JAK3/GLI2/CEBPB/ADA",30]
[49,"up","up","GO:0031960","response to corticosteroid","20/604","164/18866",{"v":3.09219757574103e-07,"d":"3.09E-07"},{"v":3.05875135706464e-05,"d":"3.06E-05"},{"v":2.31499646647851E-5,"d":"2.31E-05"},"NPAS4/IL1RN/ICAM1/MDK/FOSL1/CDKN1A/HSD11B2/IL6/AKR1C3/FAM107A/FOSB/SDC1/ZFP36L1/AGXT/EIF4EBP1/ADM/CFLAR/STC1/MSTN/GHSR",20]
[50,"up","up","GO:1990266","neutrophil migration","17/604","122/18866",{"v":3.52848626544714E-7,"d":"3.53E-07"},{"v":3.39194498796401e-05,"d":"3.39E-05"},{"v":2.56717194207042e-05,"d":"2.57E-05"},"IL1B/CCL4/MDK/CXCL1/CXCL5/C5AR1/CCL2/CXCL8/CXCL3/CCL4L1/CXCL10/LGALS3/RAC2/ITGB2/CCL3/TGFB2/PPBP",17]
[51,"up","up","GO:0061900","glial cell activation","12/604","60/18866",{"v":3.57179737212618E-7,"d":"3.57E-07"},{"v":3.39194498796401e-05,"d":"3.39E-05"},{"v":2.56717194207042e-05,"d":"2.57E-05"},"IL1B/BACE2/IL6/C5AR1/SMO/TLR8/ITGB2/CCL3/SPHK1/C1QA/TLR2/FPR2",12]
[52,"up","up","GO:0071356","cellular response to tumor necrosis factor","28/604","297/18866",{"v":3.63897543581862e-07,"d":"3.64E-07"},{"v":3.39194498796401e-05,"d":"3.39E-05"},{"v":2.56717194207042e-05,"d":"2.57E-05"},"HSPA1B/ICAM1/TNFSF14/TNFRSF11B/CCL4/CHI3L1/THBS1/GBP2/CASP4/CCL2/CXCL8/GBP3/CCL4L1/H2BC11/HAMP/LTBR/ZFP36L1/GBP1/TNFRSF1A/LTA/RELA/TNFAIP3/CCL3/TNFRSF12A/SLC2A4/SPHK1/CD40/TNFRSF8",28]
[53,"up","up","GO:0002690","positive regulation of leukocyte chemotaxis","15/604","96/18866",{"v":3.80966882986613e-07,"d":"3.81E-07"},{"v":3.48404996572851e-05,"d":"3.48E-05"},{"v":2.63688100736514E-5,"d":"2.64E-05"},"TNFSF14/CCL4/MDK/THBS1/IL6/C5AR1/CXCL8/LGALS9/CXCL10/RAC2/CCL3/MSTN/SERPINE1/CSF1/FPR2",15]
[54,"up","up","GO:0097191","extrinsic apoptotic signaling pathway","24/604","230/18866",{"v":3.9914047972678E-7,"d":"3.99E-07"},{"v":3.58265538006611e-05,"d":"3.58E-05"},{"v":2.71150988664294e-05,"d":"2.71E-05"},"IL1B/HSPA1B/IFI6/ICAM1/HMOX1/THBS1/BAG3/BCL2A1/LTBR/LGALS3/TNFRSF10C/TNFRSF10B/YAP1/TNFRSF1A/RELA/TNFAIP3/G0S2/TNFRSF12A/ITPRIP/TGFB2/CFLAR/SERPINE1/PML/HGF",24]
[55,"up","up","GO:0002698","negative regulation of immune effector process","17/604","124/18866",{"v":4.47162176162773e-07,"d":"4.47E-07"},{"v":3.94071830520175e-05,"d":"3.94E-05"},{"v":2.98250752904739e-05,"d":"2.98E-05"},"FOXJ1/HMOX1/BST2/LGALS9/MICA/LGALS3/LILRB1/HLA-B/MICB/VSIG4/TGFB2/HLA-A/HLX/CD300A/BCL6/JAK3/HLA-F",17]
[56,"up","up","GO:0046651","lymphocyte proliferation","27/604","283/18866",{"v":4.64387231036375e-07,"d":"4.64E-07"},{"v":4.01943733720234e-05,"d":"4.02E-05"},{"v":3.04208552661986e-05,"d":"3.04E-05"},"IL1B/FOXJ1/CD180/TNFSF14/CDKN1A/IL6/CD80/BTN3A1/LGALS9/LGALS3/RAC2/LILRB1/VSIG4/SLC11A1/PNP/MSN/SPTA1/ERBB2/BLK/HLA-A/CD40/CD300A/MZB1/BCL6/JAK3/CEBPB/ADA",27]
[57,"up","up","GO:0032479","regulation of type I interferon production","17/604","125/18866",{"v":5.0242665419644e-07,"d":"5.02E-07"},{"v":4.27238946121078E-5,"d":"4.27E-05"},{"v":3.23353072922363e-05,"d":"3.23E-05"},"CD14/ISG15/NFKB2/IRF7/TLR8/UBE2L6/TRIM25/IFIH1/RELA/LILRB1/NMI/TNFAIP3/IFI16/TLR2/TRIM21/HERC5/MYD88",17]
[58,"up","up","GO:0050792","regulation of viral process","23/604","217/18866",{"v":5.2713082140927e-07,"d":"5.27E-07"},{"v":4.40517774374264e-05,"d":"4.41E-05"},{"v":3.33403069439438e-05,"d":"3.33E-05"},"TOP2A/CCL4/ISG15/ZC3HAV1/BST2/CXCL8/LGALS9/TRIM25/LTF/OAS3/TRIM5/APOE/CCL3/IFI16/PLSCR1/HDAC1/MDFIC/IFITM3/TRIM21/PML/OASL/TRIM14/NECTIN2",23]
[59,"up","up","GO:0043122","regulation of I-kappaB kinase/NF-kappaB signaling","25/604","252/18866",{"v":5.97107816734958e-07,"d":"5.97E-07"},{"v":4.90539252154973e-05,"d":"4.91E-05"},{"v":3.71261506034136E-5,"d":"3.71E-05"},"IL1B/HSPB1/HMOX1/BST2/NEK6/ALPK1/LGALS9/TRIM25/LTBR/LTF/TRAF3IP2/SECTM1/TNFRSF10B/TNFRSF1A/RELA/TNFAIP3/TRIM5/TNIP2/HDAC1/RHOC/CFLAR/TRIM21/CD40/TRIM14/MYD88",25]
[60,"up","up","GO:0019058","viral life cycle","30/604","341/18866",{"v":6.17236262126649e-07,"d":"6.17E-07"},{"v":4.98624027087978e-05,"d":"4.99E-05"},{"v":3.77380416405504E-5,"d":"3.77E-05"},"HSPA1B/TOP2A/ICAM1/ISG15/CDHR3/SIGLEC1/ZC3HAV1/BST2/CD80/CCL2/CXCL8/LGALS9/TRIM25/LTF/PCSK5/OAS3/TRIM5/APOE/IFI16/PLSCR1/SLC10A1/IFITM3/SLC1A5/TRIM21/PML/OASL/CTBP2/TRIM14/NECTIN2/CLEC5A",30]
[61,"up","up","GO:0032606","type I interferon production","17/604","127/18866",{"v":6.31936902977011e-07,"d":"6.32E-07"},{"v":5.02130847332717e-05,"d":"5.02E-05"},{"v":3.80034530953388e-05,"d":"3.80E-05"},"CD14/ISG15/NFKB2/IRF7/TLR8/UBE2L6/TRIM25/IFIH1/RELA/LILRB1/NMI/TNFAIP3/IFI16/TLR2/TRIM21/HERC5/MYD88",17]
[62,"up","up","GO:0032944","regulation of mononuclear cell proliferation","23/604","221/18866",{"v":7.28269736634036e-07,"d":"7.28E-07"},{"v":5.69342486042769e-05,"d":"5.69E-05"},{"v":4.30903231268186e-05,"d":"4.31E-05"},"IL1B/FOXJ1/CDKN1A/IL6/CD80/LGALS9/LGALS3/RAC2/LILRB1/VSIG4/PNP/SPTA1/ERBB2/BLK/HLA-A/CSF1/CD40/CD300A/MZB1/BCL6/JAK3/CEBPB/ADA",23]
[63,"up","up","GO:0022407","regulation of cell-cell adhesion","35/604","439/18866",{"v":7.54998436911865e-07,"d":"7.55E-07"},{"v":5.80869432335208e-05,"d":"5.81E-05"},{"v":4.39627327090702e-05,"d":"4.40E-05"},"IL1B/FOXJ1/SELE/PLAUR/IL1RN/ICAM1/TNFSF14/MDK/IL6/CD44/FERMT3/CD80/CCL2/LGALS9/SOX2/LGALS3/RELA/LILRB1/ITGB2/VSIG4/PNP/SPTA1/ERBB2/BLK/HLA-A/HLX/ITPKB/CD300A/VNN1/FGL1/BCL6/JAK3/GLI2/CEBPB/ADA",35]
[64,"up","up","GO:0048872","homeostasis of number of cells","25/604","256/18866",{"v":8.0109422965194e-07,"d":"8.01E-07"},{"v":6.06703707987961E-5,"d":"6.07E-05"},{"v":4.59179833937008e-05,"d":"4.59E-05"},"HSPA1B/TNFSF14/SPI1/ISG15/HMOX1/IL6/SMO/LGALS9/SLC4A1/SOX9/HCLS1/ALAS2/ZFP36L1/TNFAIP3/ETV2/CCNB2/SPTA1/DYRK3/CSF1/ITPKB/HCAR2/BCL6/TCIRG1/JAK3/ADA",25]
[65,"up","up","GO:0006334","nucleosome assembly","18/604","145/18866",{"v":9.22787994649599e-07,"d":"9.23E-07"},{"v":6.88115909241017E-5,"d":"6.88E-05"},{"v":5.20796139490503e-05,"d":"5.21E-05"},"H3C13/H1-5/H1-2/H3C7/H2BC9/H2BC21/CENPA/H2BC18/KNL1/SOX9/H2BC11/H4C15/CENPM/H2BC17/H1-3/H2BC14/HJURP/H2BC3",18]
[66,"up","up","GO:0009612","response to mechanical stimulus","22/604","209/18866",{"v":1.04426173546753e-06,"d":"1.04E-06"},{"v":7.6689948966835e-05,"d":"7.67E-05"},{"v":5.80422990128283e-05,"d":"5.80E-05"},"IL1B/TNFSF14/CHI3L1/MDK/FOSL1/THBS1/CASP5/BAG3/TLR8/FOSB/SOX9/CXCL10/LTBR/MMP14/TNFRSF10B/TNFRSF1A/RELA/CD40/TNFRSF8/BDKRB1/MYD88/WNT11",22]
[67,"up","up","GO:2001236","regulation of extrinsic apoptotic signaling pathway","19/604","162/18866",{"v":1.11279677747877e-06,"d":"1.11E-06"},{"v":8.0503372842382e-05,"d":"8.05E-05"},{"v":6.09284645642342e-05,"d":"6.09E-05"},"IL1B/HSPA1B/IFI6/ICAM1/HMOX1/THBS1/LTBR/LGALS3/TNFRSF10B/YAP1/RELA/TNFAIP3/G0S2/TNFRSF12A/ITPRIP/CFLAR/SERPINE1/PML/HGF",19]
[68,"up","up","GO:0002573","myeloid leukocyte differentiation","22/604","210/18866",{"v":1.13215699307286E-6,"d":"1.13E-06"},{"v":8.05167594500166E-5,"d":"8.05E-05"},{"v":6.09385961328891e-05,"d":"6.09E-05"},"SPI1/BATF/IRF7/C1QC/CSF3/MYC/LTBR/LTF/HCLS1/ZFP36L1/LILRB1/LIF/SBNO2/PIR/CCL3/IFI16/OSCAR/TLR2/NOTCH2/CSF1/TCIRG1/CEBPB",22]
[69,"up","up","GO:0001819","positive regulation of cytokine production","35/604","447/18866",{"v":1.14620515825276e-06,"d":"1.15E-06"},{"v":8.05167594500166E-5,"d":"8.05E-05"},{"v":6.09385961328891e-05,"d":"6.09E-05"},"IL1B/HSPA1B/HSPB1/CD14/MDK/NFKB2/THBS1/IL6/IRF7/C5AR1/CD80/TLR8/OSM/LGALS9/ORM2/GSDMD/IFIH1/LTA/RELA/LILRB1/SLC11A1/CCL3/IFI16/SPHK1/TLR2/NFAM1/SERPINE1/HLA-A/CD40/MYD88/HGF/WNT11/CEBPB/CLEC5A/HLA-F",35]
[70,"up","up","GO:0045785","positive regulation of cell adhesion","34/604","428/18866",{"v":1.17957363593978E-6,"d":"1.18E-06"},{"v":8.16770487628585e-05,"d":"8.17E-05"},{"v":6.18167537030093e-05,"d":"6.18E-05"},"IL1B/SELE/PLAUR/ICAM1/TNFSF14/MDK/IL6/CD44/CD80/CCL2/LGALS9/SOX2/RREB1/RELA/LILRB1/EMILIN1/LIF/ITGB2/PNP/TGFB2/RHOD/SPTA1/ERBB2/HLA-A/HLX/CSF1/ITPKB/VNN1/CARMIL1/BCL6/JAK3/GLI2/CCN1/ADA",34]
[71,"up","up","GO:0002703","regulation of leukocyte mediated immunity","22/604","211/18866",{"v":1.22677170659716E-6,"d":"1.23E-06"},{"v":8.22502559210412e-05,"d":"8.23E-05"},{"v":6.22505818867511e-05,"d":"6.23E-05"},"IL1B/FOXJ1/ICAM1/HMOX1/IL6/BST2/MR1/LGALS9/MICA/LTA/RAC2/LILRB1/HLA-B/ITGB2/BLK/HLA-A/CD40/CD300A/BCL6/NECTIN2/JAK3/HLA-F",22]
[72,"up","up","GO:0070555","response to interleukin-1","22/604","211/18866",{"v":1.22677170659716E-6,"d":"1.23E-06"},{"v":8.22502559210412e-05,"d":"8.23E-05"},{"v":6.22505818867511e-05,"d":"6.23E-05"},"IL1B/SELE/IL1RN/ICAM1/CCL4/CHI3L1/IL6/GBP2/CCL2/CXCL8/LGALS9/GBP3/SOX9/CCL4L1/GBP1/RELA/CCL3/TNIP2/IRAK2/CD40/MYD88/CEBPB",22]
[73,"up","up","GO:0071260","cellular response to mechanical stimulus","13/604","79/18866",{"v":1.23875978589561e-06,"d":"1.24E-06"},{"v":8.22502559210412e-05,"d":"8.23E-05"},{"v":6.22505818867511e-05,"d":"6.23E-05"},"IL1B/TNFSF14/CASP5/BAG3/TLR8/SOX9/LTBR/TNFRSF10B/TNFRSF1A/CD40/TNFRSF8/MYD88/WNT11",13]
[74,"up","up","GO:2001198","regulation of dendritic cell differentiation","6/604","13/18866",{"v":1.4878508690773E-6,"d":"1.49E-06"},{"v":9.74542319245634e-05,"d":"9.75E-05"},{"v":7.37576142067483e-05,"d":"7.38E-05"},"TMEM176A/LGALS9/TMEM176B/LILRB1/HLA-B/CEBPB",6]
[75,"up","up","GO:0043903","regulation of symbiotic process","23/604","231/18866",{"v":1.57634329951735E-6,"d":"1.58E-06"},1.00762716807982E-4,{"v":7.62616199007127e-05,"d":"7.63E-05"},"TOP2A/CCL4/ISG15/ZC3HAV1/BST2/CXCL8/LGALS9/TRIM25/LTF/OAS3/TRIM5/APOE/CCL3/IFI16/PLSCR1/HDAC1/MDFIC/IFITM3/TRIM21/PML/OASL/TRIM14/NECTIN2",23]
[76,"up","up","GO:2001237","negative regulation of extrinsic apoptotic signaling pathway","15/604","107/18866",{"v":1.5874508518212e-06,"d":"1.59E-06"},1.00762716807982E-4,{"v":7.62616199007127e-05,"d":"7.63E-05"},"IL1B/HSPA1B/IFI6/ICAM1/HMOX1/THBS1/LGALS3/TNFRSF10B/YAP1/RELA/TNFAIP3/ITPRIP/CFLAR/SERPINE1/HGF",15]
[77,"up","up","GO:1905517","macrophage migration","11/604","57/18866",{"v":1.6007281192933E-6,"d":"1.60E-06"},1.00762716807982E-4,{"v":7.62616199007127e-05,"d":"7.63E-05"},"CYP19A1/MDK/THBS1/C5AR1/CCL2/LGALS3/MMP14/EMILIN1/CCL3/MSTN/CSF1",11]
[78,"up","up","GO:0071887","leukocyte apoptotic process","15/604","108/18866",{"v":1.78993477447651E-6,"d":"1.79E-06"},1.09895954018134E-4,{"v":8.31740522630814e-05,"d":"8.32E-05"},"IL6/IRF7/AURKB/LGALS9/LGALS3/HCLS1/TRAF3IP2/LILRB1/BLK/ITPKB/HCAR2/BCL6/JAK3/GHSR/ADA",15]
[79,"up","up","GO:0071347","cellular response to interleukin-1","20/604","183/18866",{"v":1.79116574529247e-06,"d":"1.79E-06"},1.09895954018134E-4,{"v":8.31740522630814e-05,"d":"8.32E-05"},"IL1B/IL1RN/ICAM1/CCL4/CHI3L1/IL6/GBP2/CCL2/CXCL8/GBP3/SOX9/CCL4L1/GBP1/RELA/CCL3/TNIP2/IRAK2/CD40/MYD88/CEBPB",20]
[80,"up","up","GO:0140014","mitotic nuclear division","26/604","286/18866",{"v":1.88280324295019E-6,"d":"1.88E-06"},0.000113014070804827,{"v":8.55339790765467e-05,"d":"8.55E-05"},"IL1B/MKI67/HSPA1B/MYBL2/UBE2C/KIF14/NEK6/AURKB/DLGAP5/KIFC1/NUSAP1/NDC80/KIF18B/PLK1/SPAG5/SPHK1/BCCIP/KIF18A/CCNB2/BUB1/BIRC5/BUB1B/MISP/NME6/CCDC8/NCAPG",26]
[81,"up","up","GO:0060337","type I interferon signaling pathway","14/604","95/18866",{"v":1.91849756483031E-6,"d":"1.92E-06"},0.000113014070804827,{"v":8.55339790765467e-05,"d":"8.55E-05"},"IFI6/ISG15/BST2/IRF7/GBP2/HLA-B/OAS3/IFITM3/HLA-A/OASL/MYD88/IFI35/HLA-F/IRF9",14]
[82,"up","up","GO:0071357","cellular response to type I interferon","14/604","95/18866",{"v":1.91849756483031E-6,"d":"1.92E-06"},0.000113014070804827,{"v":8.55339790765467e-05,"d":"8.55E-05"},"IFI6/ISG15/BST2/IRF7/GBP2/HLA-B/OAS3/IFITM3/HLA-A/OASL/MYD88/IFI35/HLA-F/IRF9",14]
[83,"up","up","GO:0002819","regulation of adaptive immune response","19/604","168/18866",{"v":1.93525229560565e-06,"d":"1.94E-06"},0.000113014070804827,{"v":8.55339790765467e-05,"d":"8.55E-05"},"IL1B/FOXJ1/IL6/IRF7/CD80/MR1/LTA/LILRB1/HLA-B/TNFAIP3/SLC11A1/HLA-A/HLX/CD40/BCL6/NECTIN2/JAK3/HLA-F/ADA",19]
[84,"up","up","GO:0002822","regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains","18/604","153/18866",{"v":2.03144431308E-6,"d":"2.03E-06"},1.1721917363689E-4,{"v":8.87165843494212e-05,"d":"8.87E-05"},"IL1B/FOXJ1/IL6/CD80/MR1/LTA/LILRB1/HLA-B/TNFAIP3/SLC11A1/HLA-A/HLX/CD40/BCL6/NECTIN2/JAK3/HLA-F/ADA",18]
[85,"up","up","GO:1903039","positive regulation of leukocyte cell-cell adhesion","23/604","235/18866",{"v":2.11789529063042e-06,"d":"2.12E-06"},1.19944407104104E-4,{"v":9.07791599269875e-05,"d":"9.08E-05"},"IL1B/SELE/ICAM1/TNFSF14/MDK/IL6/CD44/CD80/CCL2/LGALS9/RELA/LILRB1/ITGB2/PNP/SPTA1/HLA-A/HLX/ITPKB/VNN1/BCL6/JAK3/GLI2/ADA",23]
[86,"up","up","GO:0051091","positive regulation of DNA-binding transcription factor activity","25/604","270/18866",{"v":2.12816567174602e-06,"d":"2.13E-06"},1.19944407104104E-4,{"v":9.07791599269875e-05,"d":"9.08E-05"},"IL1B/HSPA1B/ICAM1/FOSL1/NFKB2/IL6/SMO/CSF3/LGALS9/TRIM25/ARHGEF5/LTF/HCLS1/RELA/TRIM5/ITGB2/SPHK1/CFLAR/TLR2/IRAK2/NFAM1/TRIM21/CD40/TRIM14/MYD88",25]
[87,"up","up","GO:0022612","gland morphogenesis","16/604","124/18866",{"v":2.20867041988219E-6,"d":"2.21E-06"},0.00012299548138211,{"v":9.30883460451182e-05,"d":"9.31E-05"},"MDK/IL6/SOX9/IGFBP5/TNFAIP3/MSN/TGFB2/CFLAR/VDR/PML/NOTCH2/CSF1/FGL1/HGF/GLI2/CEBPB",16]
[88,"up","up","GO:0051250","negative regulation of lymphocyte activation","18/604","154/18866",{"v":2.23305185921718e-06,"d":"2.23E-06"},0.00012299548138211,{"v":9.30883460451182e-05,"d":"9.31E-05"},"FOXJ1/MDK/CD80/LGALS9/MICA/LGALS3/LILRB1/TNFAIP3/VSIG4/ERBB2/BLK/HLX/CD300A/FGL1/BCL6/JAK3/CEBPB/HLA-F",18]
[89,"up","up","GO:0050670","regulation of lymphocyte proliferation","22/604","219/18866",{"v":2.28694197163178e-06,"d":"2.29E-06"},1.23394309901545E-4,{"v":9.33901968677066e-05,"d":"9.34E-05"},"IL1B/FOXJ1/CDKN1A/IL6/CD80/LGALS9/LGALS3/RAC2/LILRB1/VSIG4/PNP/SPTA1/ERBB2/BLK/HLA-A/CD40/CD300A/MZB1/BCL6/JAK3/CEBPB/ADA",22]
[90,"up","up","GO:0031663","lipopolysaccharide-mediated signaling pathway","11/604","59/18866",{"v":2.29120856016899e-06,"d":"2.29E-06"},1.23394309901545E-4,{"v":9.33901968677066e-05,"d":"9.34E-05"},"IL1B/CD180/CD14/CCL2/LTF/TNFAIP3/TRIM5/CCL3/TLR2/IRAK2/HCK",11]
[91,"up","up","GO:0071674","mononuclear cell migration","14/604","97/18866",{"v":2.47507957425968E-6,"d":"2.48E-06"},1.31831985675128E-4,{"v":9.97761979906881e-05,"d":"9.98E-05"},"CCL4/MDK/THBS1/IL6/C5AR1/CCL2/CCL4L1/CXCL10/LGALS3/CCL3/MSTN/SERPINE1/CSF1/FPR2",14]
[92,"up","up","GO:0048545","response to steroid hormone","29/604","346/18866",{"v":2.52058105744045e-06,"d":"2.52E-06"},0.000132796265058846,1.00506006695423E-4,"NPAS4/IL1RN/ICAM1/SPP1/MDK/FOSL1/CDKN1A/THBS1/HSD11B2/IL6/AKR1C3/FAM107A/FOSB/SDC1/MGARP/ZFP36L1/YAP1/NR2E1/AGXT/RELA/EIF4EBP1/ADM/HDAC1/TGFB2/CFLAR/STC1/TLR2/MSTN/GHSR",29]
[93,"up","up","GO:0072574","hepatocyte proliferation","7/604","21/18866",{"v":2.6182513891546e-06,"d":"2.62E-06"},0.000133786108773969,1.0125516360142E-4,"MDK/IL6/TNFAIP3/CFLAR/NOTCH2/FGL1/CEBPB",7]
[94,"up","up","GO:0072575","epithelial cell proliferation involved in liver morphogenesis","7/604","21/18866",{"v":2.6182513891546e-06,"d":"2.62E-06"},0.000133786108773969,1.0125516360142E-4,"MDK/IL6/TNFAIP3/CFLAR/NOTCH2/FGL1/CEBPB",7]
[95,"up","up","GO:1903708","positive regulation of hemopoiesis","21/604","204/18866",{"v":2.62217460976419e-06,"d":"2.62E-06"},0.000133786108773969,1.0125516360142E-4,"IL1B/HSPA1B/SCIN/MDK/ISG15/CD80/CSF3/LGALS9/MMP14/HCLS1/ZFP36L1/LIF/PNP/NOTCH2/HLX/CSF1/ITPKB/VNN1/BCL6/GLI2/ADA",21]
[96,"up","up","GO:0002449","lymphocyte mediated immunity","30/604","366/18866",{"v":2.6712428020281e-06,"d":"2.67E-06"},0.000134869936056564,0.000102075451371359,"IL1B/FOXJ1/ICAM1/C1QB/BATF/IL6/IRF7/C1QC/TLR8/MR1/LGALS9/C1R/BTN3A2/MICA/C1S/MYO1G/C2/LTA/LILRB1/HLA-B/SLC11A1/C4B/C1QA/BTN3A3/HLA-A/CD40/BCL6/TCIRG1/NECTIN2/HLA-F",30]
[97,"up","up","GO:0110110","positive regulation of animal organ morphogenesis","13/604","85/18866",{"v":2.90888777384992e-06,"d":"2.91E-06"},0.000145354423091243,0.000110010568549831,"MDK/SMO/SOX9/PIM1/MYC/TNFAIP3/LIF/TGFB2/CFLAR/VDR/NGFR/CSF1/WNT11",13]
[98,"up","up","GO:1903900","regulation of viral life cycle","18/604","157/18866",{"v":2.9510920328724e-06,"d":"2.95E-06"},0.000145958602891148,1.10467838180025E-4,"TOP2A/ISG15/ZC3HAV1/BST2/CXCL8/LGALS9/TRIM25/LTF/OAS3/TRIM5/IFI16/PLSCR1/IFITM3/TRIM21/PML/OASL/TRIM14/NECTIN2",18]
[99,"up","up","GO:0006323","DNA packaging","23/604","240/18866",{"v":3.03218483600452e-06,"d":"3.03E-06"},0.000148454544445595,1.12356875635043E-4,"H3C13/H1-5/H1-2/H3C7/TOP2A/H2BC9/H2BC21/CENPA/H2BC18/KNL1/SOX9/H2BC11/H4C15/CENPM/ERN2/NUSAP1/H2BC17/HDAC1/H1-3/H2BC14/HJURP/H2BC3/NCAPG",23]
[100,"up","up","GO:0034340","response to type I interferon","14/604","99/18866",{"v":3.17129023453377e-06,"d":"3.17E-06"},0.000153712437667852,1.16336278603686E-4,"IFI6/ISG15/BST2/IRF7/GBP2/HLA-B/OAS3/IFITM3/HLA-A/OASL/MYD88/IFI35/HLA-F/IRF9",14]
[101,"up","up","GO:0050866","negative regulation of cell activation","21/604","207/18866",{"v":3.31074540236551E-6,"d":"3.31E-06"},1.56613052439873E-4,1.18531590403821E-4,"FOXJ1/MDK/HMOX1/CD80/LGALS9/MICA/LGALS3/LILRB1/TNFAIP3/EMILIN1/APOE/VSIG4/ERBB2/BLK/HLX/CD300A/FGL1/BCL6/JAK3/CEBPB/HLA-F",21]
[102,"up","up","GO:1903901","negative regulation of viral life cycle","13/604","86/18866",{"v":3.32806775351906e-06,"d":"3.33E-06"},1.56613052439873E-4,1.18531590403821E-4,"ISG15/ZC3HAV1/BST2/TRIM25/LTF/OAS3/TRIM5/IFI16/PLSCR1/IFITM3/TRIM21/PML/OASL",13]
[103,"up","up","GO:2000106","regulation of leukocyte apoptotic process","13/604","86/18866",{"v":3.32806775351906e-06,"d":"3.33E-06"},1.56613052439873E-4,1.18531590403821E-4,"IRF7/AURKB/LGALS9/LGALS3/HCLS1/LILRB1/BLK/ITPKB/HCAR2/BCL6/JAK3/GHSR/ADA",13]
[104,"up","up","GO:0051092","positive regulation of NF-kappaB transcription factor activity","18/604","159/18866",{"v":3.53934877081987e-06,"d":"3.54E-06"},1.64954072040038E-4,0.000124844437918089,"IL1B/HSPA1B/ICAM1/NFKB2/LGALS9/TRIM25/LTF/RELA/TRIM5/ITGB2/SPHK1/CFLAR/TLR2/IRAK2/TRIM21/CD40/TRIM14/MYD88",18]
[105,"up","up","GO:0050921","positive regulation of chemotaxis","17/604","144/18866",{"v":3.70919504557932e-06,"d":"3.71E-06"},1.70758961462885E-4,1.29237831474304E-4,"HSPB1/TNFSF14/CCL4/MDK/THBS1/IL6/C5AR1/CXCL8/LGALS9/CXCL10/RAC2/TUBB2B/CCL3/MSTN/SERPINE1/CSF1/FPR2",17]
[106,"up","up","GO:0072576","liver morphogenesis","7/604","22/18866",{"v":3.73436144317429e-06,"d":"3.73E-06"},1.70758961462885E-4,1.29237831474304E-4,"MDK/IL6/TNFAIP3/CFLAR/NOTCH2/FGL1/CEBPB",7]
[107,"up","up","GO:0022409","positive regulation of cell-cell adhesion","25/604","279/18866",{"v":3.83413326008705e-06,"d":"3.83E-06"},0.000173682653379831,1.3145060906447E-4,"IL1B/SELE/PLAUR/ICAM1/TNFSF14/MDK/IL6/CD44/CD80/CCL2/LGALS9/SOX2/RELA/LILRB1/ITGB2/PNP/SPTA1/HLA-A/HLX/ITPKB/VNN1/BCL6/JAK3/GLI2/ADA",25]
[108,"up","up","GO:0042116","macrophage activation","14/604","101/18866",{"v":4.03673622172315E-6,"d":"4.04E-06"},0.000181167226543445,0.000137115260552682,"THBS1/IL6/C5AR1/TLR8/SBNO2/ITGB2/VSIG4/SLC11A1/CCL3/TNIP2/SPHK1/C1QA/TLR2/FPR2",14]
[109,"up","up","GO:0002467","germinal center formation","6/604","15/18866",{"v":4.10783158902187e-06,"d":"4.11E-06"},0.000182501737640179,0.000138125276769358,"FOXJ1/NFKB2/TNFAIP3/BCL6/KLHL6/ADA",6]
[110,"up","up","GO:0050673","epithelial cell proliferation","34/604","453/18866",{"v":4.14177659179279E-6,"d":"4.14E-06"},0.000182501737640179,0.000138125276769358,"SFN/MDK/HMOX1/KDF1/THBS1/IL6/C5AR1/SMO/GPBAR1/CCL2/LRG1/NUPR1/SOX9/MYC/SOX2/RREB1/MMP14/IGFBP5/ZFP36L1/YAP1/TNFAIP3/APOE/EPPK1/TGFB2/CFLAR/ERBB2/VDR/FST/NGFR/NOTCH2/FGL1/GHSR/HGF/CEBPB",34]
[111,"up","up","GO:0007015","actin filament organization","33/604","434/18866",{"v":4.35486030007175e-06,"d":"4.35E-06"},0.00018890267817155,0.00014296978780751,"SCIN/ICAM1/ASAP3/FAM107A/FSCN3/CSF3/VASP/ARHGEF5/ACTR3C/ARHGAP6/HCLS1/MYO1G/CYFIP1/RAC2/GPR65/EZR/PDLIM3/NRAP/GDPD2/PLEK/CAPG/MYO1F/RHOD/RHOC/SPTA1/XIRP1/FHOD1/DPYSL3/LCP1/CARMIL1/GHSR/HCK/WNT11",33]
[112,"up","up","GO:0045637","regulation of myeloid cell differentiation","24/604","263/18866",{"v":4.36498864353489e-06,"d":"4.36E-06"},0.00018890267817155,0.00014296978780751,"H3C13/HSPA1B/SCIN/H3C7/SPI1/ISG15/THBS1/IRF7/C1QC/CSF3/MYC/H4C15/LGALS3/LTF/HCLS1/ZFP36L1/LILRB1/LIF/CCL3/HDAC1/NOTCH2/CSF1/ITPKB/CEBPB",24]
[113,"up","up","GO:0001892","embryonic placenta development","13/604","89/18866",{"v":4.92445644474131e-06,"d":"4.92E-06"},2.08666704947214E-4,0.000157928065486202,"PLCD1/SOCS3/SNAI1/ST14/NRK/E2F7/ZFP36L1/LIF/ADM/SPINT1/ASCL2/CEBPB/CCN1",13]
[114,"up","up","GO:0008625","extrinsic apoptotic signaling pathway via death domain receptors","13/604","89/18866",{"v":4.92445644474131e-06,"d":"4.92E-06"},2.08666704947214E-4,0.000157928065486202,"ICAM1/HMOX1/THBS1/BAG3/LGALS3/TNFRSF10C/TNFRSF10B/TNFRSF1A/TNFAIP3/ITPRIP/CFLAR/SERPINE1/HGF",13]
[115,"up","up","GO:1904019","epithelial cell apoptotic process","15/604","117/18866",{"v":4.9508295995316E-6,"d":"4.95E-06"},2.08666704947214E-4,0.000157928065486202,"ICAM1/MDK/HMOX1/THBS1/IL6/AKR1C3/CCL2/NUPR1/ZFP36L1/YAP1/TNFAIP3/TNIP2/CFLAR/SERPINE1/CD40",15]
[116,"up","up","GO:0010001","glial cell differentiation","22/604","230/18866",{"v":5.109904321015E-6,"d":"5.11E-06"},2.13514708999653E-4,0.000161597246449522,"IL1B/BACE2/MDK/IL6/C5AR1/SMO/SOX9/VIM/SOX2/NR2E1/CDKN2C/RELA/LIF/PARD3/SPINT1/HDAC1/C1QA/ERBB2/TLR2/KLF15/LGI4/FPR2",22]
[117,"up","up","GO:0001649","osteoblast differentiation","22/604","231/18866",{"v":5.48185811275159e-06,"d":"5.48E-06"},0.000227098857029974,0.000171878322293651,"SPP1/SMAD1/IL6/SMO/CEBPD/SOX9/CLIC1/SNAI1/SOX2/LTF/IGFBP5/GDPD2/CCL3/WWTR1/LIMD1/TCIRG1/HGF/WNT11/GLI2/CEBPB/CLEC5A/CCN1",22]
[118,"up","up","GO:0002456","T cell mediated immunity","14/604","104/18866",{"v":5.72974333841562e-06,"d":"5.73E-06"},0.000234997178107978,1.77856116253418E-4,"IL1B/ICAM1/IL6/MR1/BTN3A2/MICA/MYO1G/LILRB1/HLA-B/SLC11A1/BTN3A3/HLA-A/NECTIN2/HLA-F",14]
[119,"up","up","GO:0048246","macrophage chemotaxis","9/604","42/18866",{"v":5.76947889309869e-06,"d":"5.77E-06"},0.000234997178107978,1.77856116253418E-4,"CYP19A1/MDK/THBS1/C5AR1/CCL2/LGALS3/CCL3/MSTN/CSF1",9]
[120,"up","up","GO:2001234","negative regulation of apoptotic signaling pathway","22/604","233/18866",{"v":6.30043688613835e-06,"d":"6.30E-06"},0.000254485146559272,0.000192605460949054,"IL1B/PLAUR/HSPA1B/IFI6/HSPB1/ICAM1/HMOX1/THBS1/CD44/SNAI1/LGALS3/TNFRSF10B/YAP1/RELA/TNFAIP3/HDAC1/ITPRIP/PTTG1IP/CFLAR/SERPINE1/VNN1/HGF",22]
[121,"up","up","GO:0045953","negative regulation of natural killer cell mediated cytotoxicity","6/604","16/18866",{"v":6.39478611023381e-06,"d":"6.39E-06"},0.000255064234608884,1.93043740047986E-4,"LGALS9/MICA/LILRB1/HLA-B/HLA-A/HLA-F",6]
[122,"up","up","GO:0031532","actin cytoskeleton reorganization","14/604","105/18866",{"v":6.42001993445096e-06,"d":"6.42E-06"},0.000255064234608884,1.93043740047986E-4,"MDK/PARVG/CLDN19/CSF3/NRK/HCLS1/GPR65/EZR/GDPD2/PLEK/RHOD/PLEK2/NOTCH2/HCK",14]
[123,"up","up","GO:0034728","nucleosome organization","19/604","183/18866",{"v":6.88470914065637e-06,"d":"6.88E-06"},0.000271302318737898,0.000205333430510804,"H3C13/H1-5/H1-2/H3C7/H2BC9/H2BC21/CENPA/H2BC18/KNL1/SOX9/H2BC11/H4C15/CENPM/H2BC17/SMARCD3/H1-3/H2BC14/HJURP/H2BC3",19]
[124,"up","up","GO:0032757","positive regulation of interleukin-8 production","10/604","54/18866",{"v":7.05311060282068e-06,"d":"7.05E-06"},0.000275696992676386,0.000208659511467148,"IL1B/HSPA1B/CD14/IL6/TLR8/LGALS9/RELA/TLR2/SERPINE1/MYD88",10]
[125,"up","up","GO:0002719","negative regulation of cytokine production involved in immune response","7/604","24/18866",{"v":7.16720798325105E-6,"d":"7.17E-06"},2.75874599702167E-4,2.08793932212448E-4,"HMOX1/BST2/LILRB1/TGFB2/BCL6/JAK3/HLA-F",7]
[126,"up","up","GO:0032611","interleukin-1 beta production","14/604","106/18866",{"v":7.18306021620375E-6,"d":"7.18E-06"},2.75874599702167E-4,2.08793932212448E-4,"IL1B/HSPB1/IL6/TLR8/MR1/ABCA1/LGALS9/ORM2/GSDMD/TNFAIP3/CCL3/IFI16/SPHK1/GHSR",14]
[127,"up","up","GO:1904018","positive regulation of vasculature development","22/604","235/18866",{"v":7.228403994672e-06,"d":"7.23E-06"},2.75874599702167E-4,2.08793932212448E-4,"IL1B/HSPB1/CHI3L1/MDK/HMOX1/THBS1/SMAD1/C5AR1/LRG1/CXCL8/NR2E1/ADM/ITGB2/SPHK1/ADM2/CFLAR/SERPINE1/CD40/GHSR/HGF/TMEM100/BTG1",22]
[128,"up","up","GO:0002291","T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell","5/604","10/18866",{"v":7.29544155014313e-06,"d":"7.30E-06"},0.00027625785307456,2.09083995084283E-4,"ICAM1/LGALS9/LGALS3/ITGAL/LILRB1",5]
[129,"up","up","GO:0002695","negative regulation of leukocyte activation","19/604","184/18866",{"v":7.45287304237762e-06,"d":"7.45E-06"},2.80031594080654E-4,0.000211940126908903,"FOXJ1/MDK/HMOX1/CD80/LGALS9/MICA/LGALS3/LILRB1/TNFAIP3/VSIG4/ERBB2/BLK/HLX/CD300A/FGL1/BCL6/JAK3/CEBPB/HLA-F",19]
[130,"up","up","GO:0002221","pattern recognition receptor signaling pathway","20/604","201/18866",{"v":7.56448458485541e-06,"d":"7.56E-06"},0.000280335091121522,0.000212169826709631,"HSPA1B/CD14/IRF7/TLR8/ALPK1/LTF/IFIH1/PIK3AP1/IRGM/RELA/TNFAIP3/MAPKAPK3/ITGB2/TNIP2/MAPKAPK2/TLR2/IRAK2/CD40/CD300A/MYD88",20]
[131,"up","up","GO:0097193","intrinsic apoptotic signaling pathway","25/604","290/18866",{"v":7.57662408436545E-6,"d":"7.58E-06"},0.000280335091121522,0.000212169826709631,"SFN/PLAUR/IFI6/HSPB1/CDKN1A/HMOX1/BCL2A1/CD44/CASP4/NUPR1/PPP1R15A/SNAI1/ERN2/ATP2A1/TNFRSF10B/TNFRSF1A/BMF/HIC1/IFI16/HDAC1/MELK/PTTG1IP/PML/VNN1/CEBPB",25]
[132,"up","up","GO:1905521","regulation of macrophage migration","9/604","44/18866",{"v":8.66398102146235e-06,"d":"8.66E-06"},0.000318138757659303,0.000240781290747977,"CYP19A1/MDK/THBS1/C5AR1/MMP14/EMILIN1/CCL3/MSTN/CSF1",9]
[133,"up","up","GO:0002285","lymphocyte activation involved in immune response","19/604","187/18866",{"v":9.41965234842621e-06,"d":"9.42E-06"},0.00034328612731445,0.000259813917168701,"CD180/ICAM1/MDK/BATF/IL6/CD80/LGALS9/LGALS3/ITGAL/LILRB1/SLC11A1/NOTCH2/LCP1/HLX/CD40/BCL6/JAK3/HLA-F/ADA",19]
[134,"up","up","GO:0002716","negative regulation of natural killer cell mediated immunity","6/604","17/18866",{"v":9.61573572556324e-06,"d":"9.62E-06"},0.000347816948222426,0.000263243040091028,"LGALS9/MICA/LILRB1/HLA-B/HLA-A/HLA-F",6]
[135,"up","up","GO:0002286","T cell activation involved in immune response","14/604","109/18866",{"v":9.97666177177425E-6,"d":"9.98E-06"},0.00035819910820585,0.000271100711693047,"ICAM1/MDK/BATF/IL6/CD80/LGALS9/LGALS3/ITGAL/LILRB1/SLC11A1/LCP1/HLX/BCL6/JAK3",14]
[136,"up","up","GO:0010951","negative regulation of endopeptidase activity","23/604","258/18866",{"v":1.0111650144599E-5,"d":"1.01E-05"},0.000360376237138761,2.72748457847737E-4,"SFN/PLAUR/IFI6/TNFSF14/SERPINA1/THBS1/BST2/CD44/SERPINH1/LTF/SERPINA5/SERPINA3/TIMP1/SPINT1/IFI16/C4B/CFLAR/BIRC5/SERPINE1/NGFR/AMBP/ITIH1/HGF",23]
[137,"up","up","GO:0051346","negative regulation of hydrolase activity","34/604","473/18866",{"v":1.0431602928755E-5,"d":"1.04E-05"},0.000369065543034127,0.000279324903624365,"SFN/PLAUR/IFI6/TNFSF14/SERPINA1/THBS1/SPOCD1/PPP1R14B/BST2/CD44/KNL1/SERPINH1/SH2D4A/CNN3/PPP1R15A/LGALS3/LTF/SERPINA5/SERPINA3/TIMP1/SPINT1/IFI16/C4B/TGFB2/CFLAR/GNAT1/BIRC5/SERPINE1/NGFR/AMBP/PLIN5/CCDC8/ITIH1/HGF",34]
[138,"up","up","GO:2001233","regulation of apoptotic signaling pathway","31/604","413/18866",{"v":1.09645209517466E-5,"d":"1.10E-05"},0.000385108935167505,0.000291467242691357,"SFN/IL1B/PLAUR/HSPA1B/IFI6/HSPB1/ICAM1/HMOX1/THBS1/CD44/NUPR1/LGALS9/SNAI1/LTBR/LGALS3/TNFRSF10B/YAP1/RELA/BMF/TNFAIP3/G0S2/TNFRSF12A/HDAC1/ITPRIP/PTTG1IP/CFLAR/SERPINE1/NGFR/PML/VNN1/HGF",31]
[139,"up","up","GO:0002526","acute inflammatory response","14/604","111/18866",{"v":1.23362875777095e-05,"d":"1.23E-05"},0.000430172560353653,0.000325573360153862,"IL1B/ICAM1/CD163/SERPINA1/IL6/OSM/NUPR1/ORM2/HAMP/SERPINA3/PLSCR1/C2CD4B/VNN1/CEBPB",14]
[140,"up","up","GO:0045766","positive regulation of angiogenesis","20/604","208/18866",{"v":1.26039401613882E-5,"d":"1.26E-05"},0.00043636641401606,0.000330261138815321,"IL1B/HSPB1/CHI3L1/MDK/HMOX1/THBS1/SMAD1/C5AR1/LRG1/CXCL8/NR2E1/ADM/ITGB2/SPHK1/ADM2/SERPINE1/CD40/GHSR/HGF/BTG1",20]
[141,"up","up","GO:1905523","positive regulation of macrophage migration","7/604","26/18866",{"v":1.28831687360448E-5,"d":"1.29E-05"},4.42870346550419E-4,0.000335183598694409,"MDK/THBS1/C5AR1/MMP14/CCL3/MSTN/CSF1",7]
[142,"up","up","GO:1902107","positive regulation of leukocyte differentiation","17/604","159/18866",{"v":1.41229411988927E-5,"d":"1.41E-05"},0.000482069690077697,0.000364851371965464,"IL1B/MDK/CD80/LGALS9/MMP14/HCLS1/ZFP36L1/LIF/PNP/NOTCH2/HLX/CSF1/ITPKB/VNN1/BCL6/GLI2/ADA",17]
[143,"up","up","GO:0006953","acute-phase response","9/604","47/18866",{"v":1.52874942613074E-5,"d":"1.53E-05"},0.000518171221570327,0.000392174585945205,"IL1B/CD163/SERPINA1/IL6/ORM2/HAMP/SERPINA3/PLSCR1/CEBPB",9]
[144,"up","up","GO:0048143","astrocyte activation","7/604","27/18866",{"v":1.69144348741121e-05,"d":"1.69E-05"},5.69042819142661E-4,0.000430676430285075,"IL1B/BACE2/IL6/C5AR1/SMO/C1QA/FPR2",7]
[145,"up","up","GO:0031497","chromatin assembly","19/604","195/18866",{"v":1.71405511852338e-05,"d":"1.71E-05"},5.69042819142661E-4,0.000430676430285075,"H3C13/H1-5/H1-2/H3C7/H2BC9/H2BC21/CENPA/H2BC18/KNL1/SOX9/H2BC11/H4C15/CENPM/H2BC17/HDAC1/H1-3/H2BC14/HJURP/H2BC3",19]
[146,"up","up","GO:0042098","T cell proliferation","19/604","195/18866",{"v":1.71405511852338e-05,"d":"1.71E-05"},5.69042819142661E-4,0.000430676430285075,"IL1B/FOXJ1/TNFSF14/IL6/CD80/BTN3A1/LGALS9/LGALS3/RAC2/LILRB1/VSIG4/SLC11A1/PNP/MSN/SPTA1/ERBB2/HLA-A/JAK3/CEBPB",19]
[147,"up","up","GO:0001701","in utero embryonic development","29/604","383/18866",{"v":1.78455821822294e-05,"d":"1.78E-05"},0.000588365484765483,0.000445300666588711,"FOSL1/MYH6/PLCD1/SLC25A34/SMO/MAFF/SLC5A7/SOCS3/CHST11/SNAI1/ST14/NRK/TENT5C/E2F7/ZFP36L1/LIF/ADM/SLC34A2/SPINT1/ETV2/CCNB2/NOTCH2/ASCL2/WNT9B/TMEM100/GLI2/CEBPB/CCN1/ADA",29]
[148,"up","up","GO:1901342","regulation of vasculature development","32/604","444/18866",{"v":1.79653583134499E-5,"d":"1.80E-05"},0.000588365484765483,0.000445300666588711,"IL1B/HSPB1/CHI3L1/MDK/HMOX1/THBS1/SMAD1/IL6/C5AR1/LRG1/CXCL8/CXCL10/NR2E1/TNFAIP3/EMILIN1/ADM/ITGB2/TNFRSF12A/SPHK1/ADM2/TGFB2/CFLAR/ERBB2/SERPINE1/NGFR/PML/NFATC1/CD40/GHSR/HGF/TMEM100/BTG1",32]
[149,"up","up","GO:1904036","negative regulation of epithelial cell apoptotic process","9/604","48/18866",{"v":1.82866177001535e-05,"d":"1.83E-05"},0.000594867355655329,0.000450221566125291,"ICAM1/MDK/HMOX1/NUPR1/YAP1/TNFAIP3/TNIP2/CFLAR/SERPINE1",9]
[150,"up","up","GO:0050727","regulation of inflammatory response","31/604","425/18866",{"v":1.92251779575574e-05,"d":"1.92E-05"},0.000621229583735205,0.000470173650400614,"IL1B/SELE/CYP19A1/MDK/CASP5/IL6/MMP3/CASP4/OSM/NUPR1/SOCS3/TNFRSF1A/LTA/PIK3AP1/RELA/TNFAIP3/APOE/SBNO2/CCL3/SPHK1/TLR2/SERPINE1/C2CD4B/MYD88/BCL6/FPR2/GHSR/HGF/HCK/CEBPB/ADA",31]
[151,"up","up","GO:0044409","entry into host","16/604","147/18866",{"v":2.00880241504554E-5,"d":"2.01E-05"},0.000644812271902367,4.88022057611274E-4,"HSPA1B/ICAM1/CDHR3/SIGLEC1/CD80/CXCL8/LGALS9/TRIM25/TRIM5/SLC10A1/IFITM3/SLC1A5/TRIM21/TRIM14/NECTIN2/CLEC5A",16]
[152,"up","up","GO:1902041","regulation of extrinsic apoptotic signaling pathway via death domain receptors","10/604","61/18866",{"v":2.1733573594255E-5,"d":"2.17E-05"},0.000689724041789466,0.0005220132443587,"ICAM1/HMOX1/THBS1/LGALS3/TNFRSF10B/TNFAIP3/ITPRIP/CFLAR/SERPINE1/HGF",10]
[153,"up","up","GO:2000107","negative regulation of leukocyte apoptotic process","9/604","49/18866",{"v":2.17717718988629e-05,"d":"2.18E-05"},0.000689724041789466,0.0005220132443587,"IRF7/AURKB/HCLS1/LILRB1/ITPKB/BCL6/JAK3/GHSR/ADA",9]
[154,"up","up","GO:0031069","hair follicle morphogenesis","7/604","28/18866",{"v":2.19332424542506E-5,"d":"2.19E-05"},6.90327442699693E-4,0.000522469924491206,"SMO/SNAI1/IGFBP5/TGFB2/FST/NGFR/GLI2",7]
[155,"up","up","GO:0002831","regulation of response to biotic stimulus","30/604","409/18866",{"v":2.35187967997513e-05,"d":"2.35E-05"},0.000735455536054157,0.000556624834275947,"IL1B/CD180/IRF7/TLR8/MR1/LGALS9/SOCS3/MICA/LTF/TRAF3IP2/IRGM/RELA/LILRB1/NMI/HLA-B/TNFAIP3/TRIM5/APOE/MICB/VSIG4/IFI16/PLSCR1/HLA-A/HERC5/DTX3L/PARP9/NECTIN2/FPR2/HCK/HLA-F",30]
[156,"up","up","GO:0010466","negative regulation of peptidase activity","23/604","272/18866",{"v":2.36897130570329E-5,"d":"2.37E-05"},0.000736051533252811,0.000557075910956543,"SFN/PLAUR/IFI6/TNFSF14/SERPINA1/THBS1/BST2/CD44/SERPINH1/LTF/SERPINA5/SERPINA3/TIMP1/SPINT1/IFI16/C4B/CFLAR/BIRC5/SERPINE1/NGFR/AMBP/ITIH1/HGF",23]
[157,"up","up","GO:1901654","response to ketone","19/604","200/18866",{"v":2.44732221479871E-5,"d":"2.45E-05"},0.000755552278670658,0.000571834925817867,"NPAS4/ICAM1/SPP1/ELK1/FOSL1/CDKN1A/THBS1/AKR1C3/FOSB/YAP1/RELA/EIF4EBP1/MSN/TGFB2/CFLAR/TLR2/MSTN/ABCB4/GHSR",19]
[158,"up","up","GO:0050868","negative regulation of T cell activation","14/604","118/18866",{"v":2.49377752269551e-05,"d":"2.49E-05"},0.000758048816007269,0.000573724414186818,"FOXJ1/MDK/CD80/LGALS9/LGALS3/LILRB1/VSIG4/ERBB2/HLX/CD300A/FGL1/BCL6/JAK3/CEBPB",14]
[159,"up","up","GO:0045824","negative regulation of innate immune response","10/604","62/18866",{"v":2.51795620456573E-5,"d":"2.52E-05"},0.000758048816007269,0.000573724414186818,"LGALS9/MICA/LILRB1/NMI/HLA-B/TNFAIP3/VSIG4/IFI16/HLA-A/HLA-F",10]
[160,"up","up","GO:0030858","positive regulation of epithelial cell differentiation","11/604","75/18866",{"v":2.52337098169078E-5,"d":"2.52E-05"},0.000758048816007269,0.000573724414186818,"SFN/FOXJ1/KDF1/PLAAT4/SOX9/LIF/ETV2/VDR/SERPINE1/TMEM100/BTG1",11]
[161,"up","up","GO:0071214","cellular response to abiotic stimulus","26/604","331/18866",{"v":2.57785507239855e-05,"d":"2.58E-05"},0.000758048816007269,0.000573724414186818,"IL1B/TNFSF14/ELK1/CDKN1A/CASP5/BAG3/AURKB/TLR8/SOX9/MYC/HAMP/LTBR/TNFRSF10B/ZFP36L1/YAP1/HVCN1/TNFRSF1A/BMF/IFI16/SLC2A4/GNAT1/MC1R/CD40/TNFRSF8/MYD88/WNT11",26]
[162,"up","up","GO:0104004","cellular response to environmental stimulus","26/604","331/18866",{"v":2.57785507239855e-05,"d":"2.58E-05"},0.000758048816007269,0.000573724414186818,"IL1B/TNFSF14/ELK1/CDKN1A/CASP5/BAG3/AURKB/TLR8/SOX9/MYC/HAMP/LTBR/TNFRSF10B/ZFP36L1/YAP1/HVCN1/TNFRSF1A/BMF/IFI16/SLC2A4/GNAT1/MC1R/CD40/TNFRSF8/MYD88/WNT11",26]
[163,"up","up","GO:0001774","microglial cell activation","9/604","50/18866",{"v":2.58052516280585e-05,"d":"2.58E-05"},0.000758048816007269,0.000573724414186818,"IL6/C5AR1/TLR8/ITGB2/CCL3/SPHK1/C1QA/TLR2/FPR2",9]
[164,"up","up","GO:0002269","leukocyte activation involved in inflammatory response","9/604","50/18866",{"v":2.58052516280585e-05,"d":"2.58E-05"},0.000758048816007269,0.000573724414186818,"IL6/C5AR1/TLR8/ITGB2/CCL3/SPHK1/C1QA/TLR2/FPR2",9]
[165,"up","up","GO:0043616","keratinocyte proliferation","9/604","50/18866",{"v":2.58052516280585e-05,"d":"2.58E-05"},0.000758048816007269,0.000573724414186818,"SFN/MDK/KDF1/ZFP36L1/YAP1/EPPK1/VDR/FST/NOTCH2",9]
[166,"up","up","GO:0046718","viral entry into host cell","15/604","134/18866",{"v":2.59963930688788E-5,"d":"2.60E-05"},0.000759063356655757,0.000574492262809402,"HSPA1B/ICAM1/CDHR3/SIGLEC1/CD80/LGALS9/TRIM25/TRIM5/SLC10A1/IFITM3/SLC1A5/TRIM21/TRIM14/NECTIN2/CLEC5A",15]
[167,"up","up","GO:0010837","regulation of keratinocyte proliferation","8/604","39/18866",{"v":2.69542425500569e-05,"d":"2.70E-05"},0.00078231864455165,0.000592092879211775,"SFN/MDK/KDF1/ZFP36L1/YAP1/EPPK1/VDR/NOTCH2",8]
[168,"up","up","GO:0050863","regulation of T cell activation","26/604","332/18866",{"v":2.71452797667508E-5,"d":"2.71E-05"},0.000783173637080007,0.000592739974856683,"IL1B/FOXJ1/TNFSF14/MDK/IL6/CD80/CCL2/LGALS9/LGALS3/RAC2/LILRB1/VSIG4/PNP/SPTA1/ERBB2/HLA-A/HLX/ITPKB/CD300A/VNN1/FGL1/BCL6/JAK3/GLI2/CEBPB/ADA",26]
[169,"up","up","GO:0002367","cytokine production involved in immune response","13/604","104/18866",{"v":2.7643397305954e-05,"d":"2.76E-05"},0.000790956063406488,0.000598630054612536,"IL1B/HMOX1/IL6/BST2/MR1/LILRB1/SLC11A1/TGFB2/TLR2/HLA-A/BCL6/JAK3/HLA-F",13]
[170,"up","up","GO:0001911","negative regulation of leukocyte mediated cytotoxicity","6/604","20/18866",{"v":2.77413927747273e-05,"d":"2.77E-05"},0.000790956063406488,0.000598630054612536,"LGALS9/MICA/LILRB1/HLA-B/HLA-A/HLA-F",6]
[171,"up","up","GO:0006333","chromatin assembly or disassembly","20/604","220/18866",{"v":2.85701083436186e-05,"d":"2.86E-05"},0.000809820556383154,0.000612907525869565,"H3C13/H1-5/H1-2/H3C7/H2BC9/H2BC21/CENPA/H2BC18/KNL1/SOX9/H2BC11/H4C15/CENPM/H2BC17/SMARCD3/HDAC1/H1-3/H2BC14/HJURP/H2BC3",20]
[172,"up","up","GO:0098773","skin epidermis development","12/604","90/18866",{"v":2.91774275543023e-05,"d":"2.92E-05"},0.000822226693928506,0.000622297031987414,"KDF1/LHX2/SMO/SOX9/SNAI1/IGFBP5/RELA/HDAC1/TGFB2/FST/NGFR/GLI2",12]
[173,"up","up","GO:0071675","regulation of mononuclear cell migration","9/604","51/18866",{"v":3.04551717913485E-5,"d":"3.05E-05"},8.43883432053862E-4,0.000638687796185966,"MDK/THBS1/C5AR1/CXCL10/LGALS3/MSTN/SERPINE1/CSF1/FPR2",9]
[174,"up","up","GO:0002064","epithelial cell development","20/604","221/18866",{"v":3.04938066131788e-05,"d":"3.05E-05"},8.43883432053862E-4,0.000638687796185966,"SFN/IL1B/FOXJ1/RAB13/ICAM1/CDKN1A/KDF1/SMO/PALLD/SOX9/VIM/SDC1/ST14/YAP1/TNFRSF1A/ARHGEF26/EZR/MSN/STC1/NOTCH2",20]
[175,"up","up","GO:0002824","positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains","13/604","105/18866",{"v":3.06423528041014e-05,"d":"3.06E-05"},8.43883432053862E-4,0.000638687796185966,"IL1B/IL6/CD80/MR1/LTA/HLA-B/SLC11A1/HLA-A/HLX/CD40/NECTIN2/HLA-F/ADA",13]
[176,"up","up","GO:1902106","negative regulation of leukocyte differentiation","13/604","105/18866",{"v":3.06423528041014e-05,"d":"3.06E-05"},8.43883432053862E-4,0.000638687796185966,"FOXJ1/MDK/C1QC/TMEM176A/MYC/LTF/TMEM176B/LILRB1/CCL3/ERBB2/HLX/BCL6/JAK3",13]
[177,"up","up","GO:0052126","movement in host environment","17/604","169/18866",{"v":3.12978785466291e-05,"d":"3.13E-05"},0.000857066764494413,0.00064866551730599,"HSPA1B/ICAM1/CDHR3/SIGLEC1/CD80/CXCL8/LGALS9/TRIM25/TRIM5/SLC10A1/IFITM3/SLC1A5/TRIM21/PML/TRIM14/NECTIN2/CLEC5A",17]
[178,"up","up","GO:0014015","positive regulation of gliogenesis","11/604","77/18866",{"v":3.24887365916272e-05,"d":"3.25E-05"},0.000884679248649535,0.000669563849922063,"IL1B/MDK/IL6/LTA/RELA/LIF/CCL3/SPINT1/HDAC1/TLR2/CSF1",11]
[179,"up","up","GO:0032612","interleukin-1 production","14/604","121/18866",{"v":3.31387282731131E-5,"d":"3.31E-05"},0.000897337519216645,0.000679144181310199,"IL1B/HSPB1/IL6/TLR8/MR1/ABCA1/LGALS9/ORM2/GSDMD/TNFAIP3/CCL3/IFI16/SPHK1/GHSR",14]
[180,"up","up","GO:0043491","protein kinase B signaling","23/604","278/18866",{"v":3.34237231814045e-05,"d":"3.34E-05"},0.000900026590334819,0.000681179387644413,"IL1B/CHI3L1/THBS1/AKR1C3/CD80/OSM/CCL2/CSF3/SOX9/HCLS1/IGFBP5/ZFP36L1/RAC2/PIK3AP1/CCL3/ERBB2/MC1R/MSTN/GDF15/KLB/CD40/HGF/TMEM100",23]
[181,"up","up","GO:0006959","humoral immune response","28/604","377/18866",{"v":3.5060053644947e-05,"d":"3.51E-05"},0.00093887337025999,0.000710580325400642,"IL1B/FOXJ1/JCHAIN/C1QB/CXCL1/CXCL5/IL6/H2BC21/C5AR1/C1QC/CCL2/CXCL8/CXCL3/H2BC11/C1R/CXCL10/LTF/C1S/C2/TRAF3IP2/LTA/VSIG4/SLC11A1/C4B/C1QA/PPBP/HLA-A/NOTCH2",28]
[182,"up","up","GO:0038066","p38MAPK cascade","9/604","52/18866",{"v":3.57957879673738e-05,"d":"3.58E-05"},0.000953308704823411,0.00072150561634643,"IL1B/GADD45G/LGALS9/GADD45B/ZFP36L1/EZR/SPHK1/MAPKAPK2/HGF",9]
[183,"up","up","GO:0007584","response to nutrient","17/604","171/18866",{"v":3.64000409901606e-05,"d":"3.64E-05"},0.000964103817919717,0.000729675828879549,"NQO1/TNFRSF11B/SPP1/HMOX1/AKR1C3/ABCA1/TRIM25/PIM1/HAMP/CXCL10/C2/LTA/RELA/VDR/STC1/CD40/ADA",17]
[184,"up","up","GO:0060713","labyrinthine layer morphogenesis","6/604","21/18866",{"v":3.77906493289563e-05,"d":"3.78E-05"},0.000995496072268756,0.000753434856472613,"SOCS3/ST14/ZFP36L1/ADM/SPINT1/CCN1",6]
[185,"up","up","GO:1902042","negative regulation of extrinsic apoptotic signaling pathway via death domain receptors","8/604","41/18866",{"v":3.95664206750023E-5,"d":"3.96E-05"},1.03664022168506E-3,0.000784574543683544,"ICAM1/HMOX1/TNFRSF10B/TNFAIP3/ITPRIP/CFLAR/SERPINE1/HGF",8]
[186,"up","up","GO:2000117","negative regulation of cysteine-type endopeptidase activity","12/604","93/18866",{"v":4.06747830785446e-05,"d":"4.07E-05"},0.00105538659841436,0.000798762619411695,"SFN/PLAUR/IFI6/TNFSF14/THBS1/CD44/LTF/IFI16/CFLAR/BIRC5/NGFR/HGF",12]
[187,"up","up","GO:0001818","negative regulation of cytokine production","27/604","360/18866",{"v":4.07174115748888e-05,"d":"4.07E-05"},0.00105538659841436,0.000798762619411695,"FOXJ1/ISG15/HMOX1/THBS1/BST2/TLR8/UBE2L6/LGALS9/TRIM25/LTF/IFIH1/GBP1/LILRB1/NMI/TNFAIP3/EZR/VSIG4/SLC11A1/TGFB2/MC1R/HERC5/BCL6/JAK3/GHSR/HGF/WNT11/HLA-F",27]
[188,"up","up","GO:0045765","regulation of angiogenesis","29/604","403/18866",{"v":4.53468484770041e-05,"d":"4.53E-05"},0.00116912858812787,0.000884847519274129,"IL1B/HSPB1/CHI3L1/MDK/HMOX1/THBS1/SMAD1/IL6/C5AR1/LRG1/CXCL8/CXCL10/NR2E1/TNFAIP3/EMILIN1/ADM/ITGB2/TNFRSF12A/SPHK1/ADM2/TGFB2/ERBB2/SERPINE1/NGFR/PML/CD40/GHSR/HGF/BTG1",29]
[189,"up","up","GO:0001889","liver development","15/604","141/18866",{"v":4.73721885881219e-05,"d":"4.74E-05"},0.00121222557413841,0.000917465198412985,"MDK/HMOX1/IL6/SOX9/HAMP/E2F7/RELA/TNFAIP3/CFLAR/NOTCH2/HLX/FGL1/HGF/CEBPB/ADA",15]
[190,"up","up","GO:0002707","negative regulation of lymphocyte mediated immunity","8/604","42/18866",{"v":4.75186422707443e-05,"d":"4.75E-05"},0.00121222557413841,0.000917465198412985,"FOXJ1/LGALS9/MICA/LILRB1/HLA-B/HLA-A/BCL6/HLA-F",8]
[191,"up","up","GO:1903707","negative regulation of hemopoiesis","16/604","158/18866",{"v":4.89940511499425e-05,"d":"4.90E-05"},0.00124332024043859,0.000940998998388259,"FOXJ1/MDK/C1QC/TMEM176A/MYC/H4C15/LTF/TMEM176B/ZFP36L1/LILRB1/CCL3/ERBB2/HLX/ITPKB/BCL6/JAK3",16]
[192,"up","up","GO:0002821","positive regulation of adaptive immune response","13/604","110/18866",{"v":5.02986771474141e-05,"d":"5.03E-05"},0.00126971451352865,0.000960975335725265,"IL1B/IL6/CD80/MR1/LTA/HLA-B/SLC11A1/HLA-A/HLX/CD40/NECTIN2/HLA-F/ADA",13]
[193,"up","up","GO:0050920","regulation of chemotaxis","20/604","229/18866",{"v":5.05580567590323e-05,"d":"5.06E-05"},0.00126971451352865,0.000960975335725265,"HSPB1/TNFSF14/CCL4/CYP19A1/MDK/THBS1/IL6/C5AR1/CCL2/CXCL8/LGALS9/CXCL10/RAC2/TUBB2B/CCL3/MSTN/SERPINE1/SLC8B1/CSF1/FPR2",20]
[194,"up","up","GO:0071496","cellular response to external stimulus","25/604","326/18866",{"v":5.43705814221202e-05,"d":"5.44E-05"},0.00135842375336607,0.00102811435841611,"IL1B/ICAM1/TNFSF14/FOSL1/CDKN1A/HMOX1/CASP5/AKR1C3/FAM107A/BAG3/TLR8/SOX9/PIM1/GSDMD/LTBR/TNFRSF10B/TNFRSF1A/CD68/IFI16/VDR/CD40/TNFRSF8/MYD88/WNT9B/WNT11",25]
[195,"up","up","GO:0048730","epidermis morphogenesis","7/604","32/18866",{"v":5.57846727283079e-05,"d":"5.58E-05"},0.0013866067113544,1.04944445051635E-3,"SMO/SNAI1/IGFBP5/TGFB2/FST/NGFR/GLI2",7]
[196,"up","up","GO:0032655","regulation of interleukin-12 production","9/604","55/18866",{"v":5.68032107446485e-05,"d":"5.68E-05"},0.00139758965725539,0.00105775682311034,"MDK/THBS1/TLR8/LGALS9/LILRB1/HLA-B/TLR2/CD40/JAK3",9]
[197,"up","up","GO:0070741","response to interleukin-6","9/604","55/18866",{"v":5.68032107446485e-05,"d":"5.68E-05"},0.00139758965725539,0.00105775682311034,"ICAM1/SPI1/CHI3L1/IL6/SOCS3/HAMP/YAP1/RELA/SBNO2",9]
[198,"up","up","GO:0048568","embryonic organ development","31/604","451/18866",{"v":5.93796171423093e-05,"d":"5.94E-05"},0.00145360103176148,1.10014867485884E-3,"PLCD1/SMO/CXCL8/SOX9/SOCS3/CHST11/SNAI1/ST14/NRK/MMP14/PCSK5/USH1G/E2F7/ZFP36L1/YAP1/TEAD4/LIF/ADM/TUBB2B/SPINT1/TGFB2/GRHL3/NOTCH2/HLX/ASCL2/WNT9B/WNT11/GLI2/CEBPB/CCN1/ADA",31]
[199,"up","up","GO:0061008","hepaticobiliary system development","15/604","144/18866",{"v":6.04875501407778e-05,"d":"6.05E-05"},0.00147328218860477,0.00111504423295747,"MDK/HMOX1/IL6/SOX9/HAMP/E2F7/RELA/TNFAIP3/CFLAR/NOTCH2/HLX/FGL1/HGF/CEBPB/ADA",15]
[200,"up","up","GO:0014013","regulation of gliogenesis","14/604","128/18866",{"v":6.20277698912137e-05,"d":"6.20E-05"},0.00150324300331357,0.00113771988458358,"IL1B/MDK/IL6/PITX3/NR2E1/LTA/RELA/LIF/CCL3/SPINT1/HDAC1/TLR2/CSF1/ASCL2",14]
[201,"up","up","GO:0048708","astrocyte differentiation","11/604","83/18866",{"v":6.60060184536744e-05,"d":"6.60E-05"},1.5893525901266E-3,0.0012028913764545,"IL1B/BACE2/IL6/C5AR1/SMO/SOX9/VIM/NR2E1/LIF/C1QA/FPR2",11]
[202,"up","up","GO:0072677","eosinophil migration","6/604","23/18866",{"v":6.65645916640601e-05,"d":"6.66E-05"},1.5893525901266E-3,0.0012028913764545,"CCL4/CCL2/CCL4L1/LGALS3/CCL3/CD300A",6]
[203,"up","up","GO:1904996","positive regulation of leukocyte adhesion to vascular endothelial cell","6/604","23/18866",{"v":6.65645916640601e-05,"d":"6.66E-05"},1.5893525901266E-3,0.0012028913764545,"SELE/ICAM1/MDK/IL6/RELA/ITGB2",6]
[204,"up","up","GO:0001503","ossification","29/604","412/18866",{"v":6.72606878935789e-05,"d":"6.73E-05"},0.00159810075598126,1.20951237001611E-3,"SPP1/MDK/ISG15/SMAD1/IL6/SMO/CEBPD/SOX9/CLIC1/SNAI1/SOX2/LTF/MMP14/IGFBP5/SBNO2/GDPD2/CCL3/WWTR1/TGFB2/STC1/LIMD1/CSF1/TCIRG1/HGF/WNT11/GLI2/CEBPB/CLEC5A/CCN1",29]
[205,"up","up","GO:0002832","negative regulation of response to biotic stimulus","12/604","98/18866",{"v":6.86048773369814e-05,"d":"6.86E-05"},0.00162208702659682,0.00122766622603019,"LGALS9/MICA/LTF/LILRB1/NMI/HLA-B/TNFAIP3/MICB/VSIG4/IFI16/HLA-A/HLA-F",12]
[206,"up","up","GO:0051090","regulation of DNA-binding transcription factor activity","31/604","455/18866",{"v":6.99197097255503e-05,"d":"6.99E-05"},0.0016451496749502,0.0012451210444228,"IL1B/FOXJ1/HSPA1B/ICAM1/FOSL1/NFKB2/HMOX1/IL6/SMO/CSF3/NUPR1/LGALS9/TRIM25/PIM1/ARHGEF5/LTF/HCLS1/RELA/TNFAIP3/TRIM5/ITGB2/SPHK1/CFLAR/TLR2/IRAK2/NFAM1/TRIM21/CD40/TRIM14/MYD88/HCK",31]
[207,"up","up","GO:0052548","regulation of endopeptidase activity","30/604","434/18866",{"v":7.03289986150861e-05,"d":"7.03E-05"},1.64678577916581E-3,1.24635931946898E-3,"SFN/PLAUR/IFI6/TNFSF14/SERPINA1/THBS1/BST2/CD44/SERPINH1/LGALS9/MYC/SOX2/LTF/SERPINA5/SERPINA3/TNFRSF10B/TIMP1/SPINT1/IFI16/HDAC1/C4B/CFLAR/BIRC5/SERPINE1/NGFR/PML/AMBP/ITIH1/HGF/CCN1",30]
[208,"up","up","GO:0019932","second-messenger-mediated signaling","31/604","456/18866",{"v":7.28058274259822e-05,"d":"7.28E-05"},0.00169658579583527,0.00128405014463334,"SELE/CCL4/MAFA/THBS1/CXCL8/FPR1/ABCA1/GPR101/SOX9/DDAH2/CXCL10/GBP1/IRGM/GPR65/ADM/APOE/PLEK/LHCGR/CCL3/HAP1/SPHK1/ADM2/ADGRE1/MC1R/IRAG1/NFATC1/RAMP1/MC4R/FPR2/TMEM100/ADA",31]
[209,"up","up","GO:0045619","regulation of lymphocyte differentiation","17/604","181/18866",{"v":7.46321405562418e-05,"d":"7.46E-05"},0.00173082289605791,0.00130996227569128,"IL1B/FOXJ1/MDK/CD80/LGALS9/MMP14/ZFP36L1/PNP/ERBB2/NFAM1/HLX/ITPKB/VNN1/BCL6/JAK3/GLI2/ADA",17]
[210,"up","up","GO:0032615","interleukin-12 production","9/604","57/18866",{"v":7.59284287325729e-05,"d":"7.59E-05"},1.74767853589608E-3,0.00132271935925593,"MDK/THBS1/TLR8/LGALS9/LILRB1/HLA-B/TLR2/CD40/JAK3",9]
[211,"up","up","GO:0042362","fat-soluble vitamin biosynthetic process","5/604","15/18866",{"v":7.60800848100006e-05,"d":"7.61E-05"},1.74767853589608E-3,0.00132271935925593,"IL1B/SNAI1/PLTP/VDR/BCO1",5]
[212,"up","up","GO:0014002","astrocyte development","8/604","45/18866",{"v":7.97543730985833e-05,"d":"7.98E-05"},0.00181488003008842,1.37358038175717E-3,"IL1B/BACE2/IL6/C5AR1/SMO/VIM/C1QA/FPR2",8]
[213,"up","up","GO:0052372","modulation by symbiont of entry into host","8/604","45/18866",{"v":7.97543730985833e-05,"d":"7.98E-05"},0.00181488003008842,1.37358038175717E-3,"CXCL8/LGALS9/TRIM25/TRIM5/IFITM3/TRIM21/TRIM14/NECTIN2",8]
[214,"up","up","GO:0043297","apical junction assembly","11/604","85/18866",{"v":8.23528666354331e-05,"d":"8.24E-05"},1.8652539466446E-3,1.41170555939245E-3,"RAB13/GPBAR1/CLDN19/PARD6G/SNAI1/PARD3/CLDN23/RHOC/CRB3/CLDN2/WNT11",11]
[215,"up","up","GO:0031342","negative regulation of cell killing","6/604","24/18866",{"v":8.63637195576628e-05,"d":"8.64E-05"},1.94699976137671E-3,0.00147357435818093,"LGALS9/MICA/LILRB1/HLA-B/HLA-A/HLA-F",6]
[216,"up","up","GO:0007163","establishment or maintenance of cell polarity","19/604","220/18866",{"v":8.98851133593783e-05,"d":"8.99E-05"},0.00201519408065902,1.52518679402272E-3,"FOXJ1/CCL4/CENPA/LHX2/PARVG/FSCN3/PARD6G/WEE1/NDC80/RAC2/PLK1/PARD3/MSN/RHOD/RHOC/BCCIP/MISP/TCIRG1/WNT11",19]
[217,"up","up","GO:1901653","cellular response to peptide","28/604","398/18866",{"v":9.02201599964944e-05,"d":"9.02E-05"},0.00201519408065902,1.52518679402272E-3,"IL1B/RAB13/ICAM1/CASP4/SOCS3/VIM/MGARP/CYFIP1/ZFP36L1/RELA/CYP11A1/EIF4EBP1/LHCGR/SLC2A4/ATP6V0E1/BCAR3/AGTRAP/CFLAR/MSTN/KLF15/NGFR/GDF15/MZB1/TCIRG1/JAK3/FPR2/GHSR/LPIN3",28]
[218,"up","up","GO:0001776","leukocyte homeostasis","11/604","86/18866",{"v":9.17479112922749e-05,"d":"9.17E-05"},0.0020399180093287,1.54389894183282E-3,"TNFSF14/IL6/LGALS9/TNFAIP3/CCNB2/SPTA1/ITPKB/HCAR2/TCIRG1/JAK3/ADA",11]
[219,"up","up","GO:0048732","gland development","30/604","443/18866",1.01578579579203E-4,0.00224817979552692,1.70152054714502E-3,"CYP19A1/MDK/HMOX1/IL6/SMO/SOX9/TG/HAMP/SOX2/RREB1/SERPINA5/E2F7/IGFBP5/RELA/TNFAIP3/MSN/TGFB2/CFLAR/CCNB2/VDR/PML/NOTCH2/HLX/CSF1/FGL1/HGF/WNT11/GLI2/CEBPB/ADA",30]
[220,"up","up","GO:0001942","hair follicle development","11/604","87/18866",1.02043452627514E-4,2.24820279493437E-3,1.70153795409994E-3,"LHX2/SMO/SOX9/SNAI1/IGFBP5/RELA/HDAC1/TGFB2/FST/NGFR/GLI2",11]
[221,"up","up","GO:0032956","regulation of actin cytoskeleton organization","26/604","360/18866",0.000104596427715763,0.00229402210469819,1.73621600661792E-3,"SCIN/ICAM1/ASAP3/MDK/FAM107A/BST2/CSF3/VASP/ARHGEF5/ACTR3C/ARHGAP6/HCLS1/CYFIP1/RAC2/GPR65/PLEK/CAPG/RHOD/RHOC/SPTA1/GRHL3/FHOD1/NOTCH2/CARMIL1/HCK/WNT11",26]
[222,"up","up","GO:0002699","positive regulation of immune effector process","19/604","223/18866",1.07571721379214E-4,0.00234864925011284,1.77756021340238E-3,"IL1B/HMOX1/IL6/CD80/MR1/LGALS9/LTA/RAC2/LILRB1/HLA-B/ITGB2/BLK/HLA-A/HLX/CD40/CD300A/MZB1/NECTIN2/HLA-F",19]
[223,"up","up","GO:0032480","negative regulation of type I interferon production","8/604","47/18866",1.09986326468766E-4,0.00237992734104512,0.00180123283714121,"ISG15/UBE2L6/TRIM25/IFIH1/LILRB1/NMI/TNFAIP3/HERC5",8]
[224,"up","up","GO:0035850","epithelial cell differentiation involved in kidney development","8/604","47/18866",1.09986326468766E-4,0.00237992734104512,0.00180123283714121,"FOXJ1/SMO/YAP1/LIF/WWTR1/KLF15/NOTCH2/WNT9B",8]
[225,"up","up","GO:0060669","embryonic placenta morphogenesis","6/604","25/18866",0.000110579404960882,2.38212611486841E-3,1.8028969650932E-3,"SOCS3/ST14/ZFP36L1/ADM/SPINT1/CCN1",6]
[226,"up","up","GO:0002224","toll-like receptor signaling pathway","15/604","152/18866",0.00011215776387933,2.40543664390759E-3,1.82053939040273E-3,"CD14/IRF7/TLR8/LTF/PIK3AP1/TNFAIP3/MAPKAPK3/ITGB2/TNIP2/MAPKAPK2/TLR2/IRAK2/CD40/CD300A/MYD88",15]
[227,"up","up","GO:0043434","response to peptide hormone","30/604","447/18866",0.000119100638723919,0.00254308720658517,0.00192471934130701,"IL1B/RAB13/ICAM1/HSD11B2/SOCS3/MGARP/CYFIP1/IGFBP5/ZFP36L1/TIMP1/RELA/CYP11A1/EIF4EBP1/ADM/LHCGR/SLC2A4/ATP6V0E1/BCAR3/AGTRAP/CFLAR/TLR2/MSTN/KLF15/GDF15/MZB1/MC4R/TCIRG1/JAK3/GHSR/LPIN3",30]
[228,"up","up","GO:0032970","regulation of actin filament-based process","28/604","405/18866",1.21311840207163E-4,2.57894074335139E-3,1.95185486205892E-3,"SCIN/ICAM1/ASAP3/MDK/FAM107A/BST2/CSF3/VASP/ARHGEF5/ACTR3C/ARHGAP6/ATP2A1/HCLS1/CYFIP1/RAC2/GPR65/PLEK/CAPG/RHOD/RHOC/SPTA1/GRHL3/STC1/FHOD1/NOTCH2/CARMIL1/HCK/WNT11",28]
[229,"up","up","GO:0032868","response to insulin","22/604","283/18866",0.000123304973126146,0.00259789107650412,1.96619730090601E-3,"IL1B/RAB13/ICAM1/HSD11B2/SOCS3/CYFIP1/ZFP36L1/RELA/EIF4EBP1/ADM/SLC2A4/ATP6V0E1/BCAR3/CFLAR/TLR2/MSTN/KLF15/MZB1/MC4R/TCIRG1/GHSR/LPIN3",22]
[230,"up","up","GO:0002701","negative regulation of production of molecular mediator of immune response","7/604","36/18866",0.000123811190153178,0.00259789107650412,1.96619730090601E-3,"HMOX1/BST2/LILRB1/TGFB2/BCL6/JAK3/HLA-F",7]
[231,"up","up","GO:0002755","MyD88-dependent toll-like receptor signaling pathway","7/604","36/18866",0.000123811190153178,0.00259789107650412,1.96619730090601E-3,"CD14/IRF7/TLR8/TLR2/IRAK2/CD300A/MYD88",7]
[232,"up","up","GO:0022404","molting cycle process","11/604","89/18866",1.25616942392144E-4,2.60935813179614E-3,0.00197487606860664,"LHX2/SMO/SOX9/SNAI1/IGFBP5/RELA/HDAC1/TGFB2/FST/NGFR/GLI2",11]
[233,"up","up","GO:0022405","hair cycle process","11/604","89/18866",1.25616942392144E-4,2.60935813179614E-3,0.00197487606860664,"LHX2/SMO/SOX9/SNAI1/IGFBP5/RELA/HDAC1/TGFB2/FST/NGFR/GLI2",11]
[234,"up","up","GO:0051302","regulation of cell division","16/604","171/18866",0.000125972725983143,2.60935813179614E-3,0.00197487606860664,"SFN/IL1B/MDK/KDF1/KIF14/AURKB/OSM/KIF20A/MYC/E2F7/KIF18B/PLK1/TGFB2/PPBP/PLK5/WNT9B",16]
[235,"up","up","GO:1903038","negative regulation of leukocyte cell-cell adhesion","14/604","137/18866",0.000129800430335951,0.00266304409316831,0.00201550794624816,"FOXJ1/MDK/CD80/LGALS9/LGALS3/LILRB1/VSIG4/ERBB2/HLX/CD300A/FGL1/BCL6/JAK3/CEBPB",14]
[236,"up","up","GO:0002262","myeloid cell homeostasis","15/604","154/18866",1.29924775125928E-4,0.00266304409316831,0.00201550794624816,"HSPA1B/SPI1/ISG15/HMOX1/IL6/SLC4A1/HCLS1/ALAS2/ZFP36L1/ETV2/DYRK3/ITPKB/HCAR2/BCL6/JAK3",15]
[237,"up","up","GO:0045071","negative regulation of viral genome replication","9/604","61/18866",0.000130644183390255,0.00266304409316831,0.00201550794624816,"ISG15/ZC3HAV1/BST2/LTF/OAS3/IFI16/PLSCR1/IFITM3/OASL",9]
[238,"up","up","GO:0000280","nuclear division","29/604","428/18866",0.000130762222854149,0.00266304409316831,0.00201550794624816,"IL1B/MKI67/HSPA1B/TOP2A/MYBL2/UBE2C/KIF14/NEK6/AURKB/DLGAP5/KIFC1/NUSAP1/NDC80/KIF18B/PLK1/LIF/SPAG5/SPHK1/BCCIP/KIF18A/CCNB2/BUB1/BIRC5/BUB1B/MISP/NME6/CCDC8/TEX19/NCAPG",29]
[239,"up","up","GO:0045621","positive regulation of lymphocyte differentiation","12/604","105/18866",0.000134564854386855,0.00272902028959451,0.00206544160994579,"IL1B/MDK/CD80/LGALS9/MMP14/PNP/HLX/ITPKB/VNN1/BCL6/GLI2/ADA",12]
[240,"up","up","GO:0070371","ERK1 and ERK2 cascade","24/604","325/18866",0.000136388738753214,2.75448423640344E-3,0.00208471383576732,"IL1B/ICAM1/CCL4/CHI3L1/CD44/C5AR1/GPBAR1/CCL2/LGALS9/SOX9/CCL4L1/MYC/ZFP36L1/GBP1/EMILIN1/LIF/EZR/APOE/CCL3/CFLAR/ERBB2/NOTCH2/FPR2/CCN1",24]
[241,"up","up","GO:0031667","response to nutrient levels","31/604","473/18866",1.41415236951886E-4,0.00284414793985805,0.00215257523816257,"NQO1/ICAM1/TNFRSF11B/SPP1/CDKN1A/HMOX1/HSD11B2/AKR1C3/FAM107A/ABCA1/TRIM25/PIM1/HAMP/CXCL10/C2/LTA/CD68/RELA/EIF4EBP1/ADM/APOE/IFI16/VDR/STC1/GDF15/CD40/MC4R/GHSR/WNT9B/WNT11/ADA",31]
[242,"up","up","GO:1905314","semi-lunar valve development","7/604","37/18866",0.000148524688445443,0.0029631181063919,2.2426170503243E-3,"SOX9/SNAI1/TNFRSF1A/EMILIN1/TGFB2/NOTCH2/NFATC1",7]
[243,"up","up","GO:0071384","cellular response to corticosteroid stimulus","9/604","62/18866",1.48553270033677E-4,0.0029631181063919,2.2426170503243E-3,"NPAS4/ICAM1/AKR1C3/FAM107A/ZFP36L1/EIF4EBP1/CFLAR/STC1/MSTN",9]
[244,"up","up","GO:0051656","establishment of organelle localization","29/604","432/18866",0.000153348379461298,0.00304025473761392,0.00230099741795457,"SERPINA1/HMOX1/GEM/CENPA/KIF14/AURKB/DLGAP5/LGALS9/KIFC1/NUSAP1/NDC80/MYO1G/MGARP/RAC2/PLK1/EZR/SPAG5/PARD3/HAP1/SLC2A4/MYO1F/BCCIP/KIF18A/BLK/MISP/FHOD1/CD300A/TCIRG1/NECTIN2",29]
[245,"up","up","GO:0045682","regulation of epidermis development","11/604","91/18866",0.000153674935158946,0.00304025473761392,0.00230099741795457,"SFN/KDF1/SMO/MAFF/PLAAT4/MYCL/ZFP36L1/TGFB2/VDR/FST/NGFR",11]
[246,"up","up","GO:0051017","actin filament bundle assembly","15/604","157/18866",0.000161154756909843,0.00317527279163418,0.00240318497146257,"ASAP3/FAM107A/FSCN3/ARHGEF5/ARHGAP6/GPR65/EZR/PLEK/RHOD/RHOC/FHOD1/DPYSL3/LCP1/CARMIL1/WNT11",15]
[247,"up","up","GO:0070830","bicellular tight junction assembly","10/604","77/18866",1.67149470892519E-4,3.28005459682607E-3,2.48248841278683E-3,"RAB13/GPBAR1/CLDN19/PARD6G/SNAI1/PARD3/CLDN23/CRB3/CLDN2/WNT11",10]
[248,"up","up","GO:0030278","regulation of ossification","18/604","212/18866",1.69208177799938E-4,0.00328804308135768,2.4885344463817E-3,"MDK/ISG15/SMAD1/IL6/CEBPD/SOX9/CLIC1/LTF/IGFBP5/GDPD2/CCL3/TGFB2/LIMD1/CSF1/TCIRG1/HGF/CEBPB/CCN1",18]
[249,"up","up","GO:0051701","interaction with host","18/604","212/18866",1.69208177799938E-4,0.00328804308135768,2.4885344463817E-3,"HSPA1B/ICAM1/CDHR3/SIGLEC1/CD80/CXCL8/LGALS9/TRIM25/IRGM/TRIM5/SLC10A1/IFITM3/SLC1A5/TRIM21/PML/TRIM14/NECTIN2/CLEC5A",18]
[250,"up","up","GO:0045582","positive regulation of T cell differentiation","11/604","92/18866",1.69591658828021E-4,0.00328804308135768,2.4885344463817E-3,"IL1B/MDK/CD80/LGALS9/PNP/HLX/ITPKB/VNN1/BCL6/GLI2/ADA",11]
[251,"up","up","GO:0032897","negative regulation of viral transcription","6/604","27/18866",0.000175023658958109,0.00335312124494054,2.5377884396464E-3,"CCL4/CCL3/HDAC1/IFITM3/TRIM21/TRIM14",6]
[252,"up","up","GO:0033081","regulation of T cell differentiation in thymus","6/604","27/18866",0.000175023658958109,0.00335312124494054,2.5377884396464E-3,"IL1B/FOXJ1/ERBB2/VNN1/GLI2/ADA",6]
[253,"up","up","GO:1901623","regulation of lymphocyte chemotaxis","6/604","27/18866",0.000175023658958109,0.00335312124494054,2.5377884396464E-3,"TNFSF14/CCL4/CCL2/CXCL10/CCL3/SLC8B1",6]
[254,"up","up","GO:0046596","regulation of viral entry into host cell","7/604","38/18866",0.000177086208221886,3.37927894193497E-3,2.55758572587349E-3,"LGALS9/TRIM25/TRIM5/IFITM3/TRIM21/TRIM14/NECTIN2",7]
[255,"up","up","GO:0050870","positive regulation of T cell activation","18/604","214/18866",1.9023591266117E-4,0.00361597438693603,0.00273672716459928,"IL1B/TNFSF14/MDK/IL6/CD80/CCL2/LGALS9/LILRB1/PNP/SPTA1/HLA-A/HLX/ITPKB/VNN1/BCL6/JAK3/GLI2/ADA",18]
[256,"up","up","GO:0050678","regulation of epithelial cell proliferation","27/604","395/18866",1.91839226020942E-4,3.63220597079495E-3,0.00274901193537411,"SFN/MDK/HMOX1/KDF1/THBS1/C5AR1/SMO/GPBAR1/CCL2/LRG1/NUPR1/SOX9/MYC/SOX2/RREB1/ZFP36L1/YAP1/TNFAIP3/APOE/EPPK1/TGFB2/CFLAR/ERBB2/VDR/NGFR/NOTCH2/GHSR",27]
[257,"up","up","GO:0071354","cellular response to interleukin-6","8/604","51/18866",0.000199051972717383,0.00375410471502395,0.00284127022289609,"ICAM1/SPI1/IL6/SOCS3/HAMP/YAP1/RELA/SBNO2",8]
[258,"up","up","GO:0051897","positive regulation of protein kinase B signaling","16/604","178/18866",0.00020067898386108,0.00377012028982424,0.00285339150859185,"CHI3L1/THBS1/AKR1C3/CD80/OSM/CSF3/HCLS1/IGFBP5/RAC2/PIK3AP1/CCL3/ERBB2/MC1R/GDF15/KLB/HGF",16]
[259,"up","up","GO:0045778","positive regulation of ossification","11/604","94/18866",2.05650606033694E-4,0.00384860419863055,0.00291279155467353,"ISG15/SMAD1/IL6/CEBPD/CLIC1/LTF/GDPD2/TGFB2/HGF/CEBPB/CCN1",11]
[260,"up","up","GO:0120192","tight junction assembly","10/604","79/18866",2.07319418355741E-4,3.86491238757799E-3,0.00292513430352129,"RAB13/GPBAR1/CLDN19/PARD6G/SNAI1/PARD3/CLDN23/CRB3/CLDN2/WNT11",10]
[261,"up","up","GO:0000070","mitotic sister chromatid segregation","15/604","161/18866",0.000212793435474405,3.93667855627649E-3,0.00297945007082483,"UBE2C/KIF14/NEK6/AURKB/DLGAP5/KIFC1/NUSAP1/NDC80/KIF18B/PLK1/SPAG5/KIF18A/BUB1/BUB1B/NCAPG",15]
[262,"up","up","GO:0061572","actin filament bundle organization","15/604","161/18866",0.000212793435474405,3.93667855627649E-3,0.00297945007082483,"ASAP3/FAM107A/FSCN3/ARHGEF5/ARHGAP6/GPR65/EZR/PLEK/RHOD/RHOC/FHOD1/DPYSL3/LCP1/CARMIL1/WNT11",15]
[263,"up","up","GO:0019079","viral genome replication","13/604","127/18866",0.000220003058274573,0.00405458107778271,3.06868384265313E-3,"TOP2A/ISG15/ZC3HAV1/BST2/CCL2/CXCL8/LTF/OAS3/IFI16/PLSCR1/IFITM3/OASL/CTBP2",13]
[264,"up","up","GO:0050867","positive regulation of cell activation","28/604","421/18866",0.000230961844407416,0.0042404244691013,0.00320933822870751,"IL1B/TNFSF14/MDK/CDKN1A/THBS1/IL6/CD80/CCL2/LGALS9/MMP14/LILRB1/PLEK/ITGB2/CCL3/PNP/TNIP2/SPTA1/HLA-A/HLX/ITPKB/CD40/VNN1/BCL6/NECTIN2/JAK3/GLI2/HLA-F/ADA",28]
[265,"up","up","GO:0045669","positive regulation of osteoblast differentiation","9/604","66/18866",2.41984598754577E-4,0.00442603528363561,0.00334981659050527,"SMAD1/IL6/CEBPD/CLIC1/LTF/GDPD2/HGF/CEBPB/CCN1",9]
[266,"up","up","GO:0007088","regulation of mitotic nuclear division","15/604","163/18866",2.43590680889579E-4,4.43866176793905E-3,0.00335937286466237,"IL1B/MKI67/HSPA1B/UBE2C/NEK6/AURKB/DLGAP5/NUSAP1/NDC80/PLK1/SPHK1/BUB1/BUB1B/NME6/CCDC8",15]
[267,"up","up","GO:0052547","regulation of peptidase activity","30/604","466/18866",2.45128568299588E-4,0.00444995569493672,3.36792060131703E-3,"SFN/PLAUR/IFI6/TNFSF14/SERPINA1/THBS1/BST2/CD44/SERPINH1/LGALS9/MYC/SOX2/LTF/SERPINA5/SERPINA3/TNFRSF10B/TIMP1/SPINT1/IFI16/HDAC1/C4B/CFLAR/BIRC5/SERPINE1/NGFR/PML/AMBP/ITIH1/HGF/CCN1",30]
[268,"up","up","GO:0001666","response to hypoxia","25/604","359/18866",2.47447118733384E-4,0.00445976910412179,0.00337534781750284,"ICAM1/HMOX1/THBS1/HSD11B2/MYC/UCP2/MMP14/ALAS2/MGARP/ZFP36L1/LTA/EIF4EBP1/ADM/SOD3/SLC2A4/AGTRAP/TGFB2/CFLAR/STC1/TLR2/LIMD1/PML/PLOD1/ASCL2/ADA",25]
[269,"up","up","GO:0050691","regulation of defense response to virus by host","7/604","40/18866",0.000247509364350889,0.00445976910412179,0.00337534781750284,"IL1B/TRAF3IP2/LILRB1/TNFAIP3/MICB/DTX3L/PARP9",7]
[270,"up","up","GO:0046631","alpha-beta T cell activation","14/604","146/18866",2.54135760716209E-4,0.00456220752663506,3.45287768458475E-3,"BATF/IL6/CD80/LGALS9/LILRB1/PNP/HLA-A/HLX/ITPKB/CD300A/BCL6/TCIRG1/JAK3/ADA",14]
[271,"up","up","GO:0002576","platelet degranulation","13/604","129/18866",0.000256945083640453,0.0045956192634881,0.00347816514463771,"SERPINA1/THBS1/FERMT3/ORM2/SERPINA3/TIMP1/PLEK/TGFB2/PPBP/TOR4A/SERPINE1/BLK/HGF",13]
[272,"up","up","GO:0032731","positive regulation of interleukin-1 beta production","8/604","53/18866",0.000261948621727144,0.00466788591732156,0.00353285970092529,"HSPB1/IL6/TLR8/LGALS9/ORM2/GSDMD/CCL3/IFI16",8]
[273,"up","up","GO:0010759","positive regulation of macrophage chemotaxis","5/604","19/18866",0.000264871971682492,0.0046855271779016,0.00354621137654047,"MDK/THBS1/C5AR1/MSTN/CSF1",5]
[274,"up","up","GO:0048245","eosinophil chemotaxis","5/604","19/18866",0.000264871971682492,0.0046855271779016,0.00354621137654047,"CCL4/CCL2/CCL4L1/LGALS3/CCL3",5]
[275,"up","up","GO:0002548","monocyte chemotaxis","9/604","67/18866",0.000271726404723812,0.00475583505963302,0.00359942344864888,"CCL4/IL6/CCL2/CCL4L1/CXCL10/LGALS3/CCL3/SERPINE1/FPR2",9]
[276,"up","up","GO:0032651","regulation of interleukin-1 beta production","11/604","97/18866",0.000271790037449628,0.00475583505963302,0.00359942344864888,"HSPB1/IL6/TLR8/LGALS9/ORM2/GSDMD/TNFAIP3/CCL3/IFI16/SPHK1/GHSR",11]
[277,"up","up","GO:0046634","regulation of alpha-beta T cell activation","11/604","97/18866",0.000271790037449628,0.00475583505963302,0.00359942344864888,"CD80/LGALS9/LILRB1/PNP/HLA-A/HLX/ITPKB/CD300A/BCL6/JAK3/ADA",11]
[278,"up","up","GO:0007051","spindle organization","16/604","183/18866",0.000275266146490688,4.79933457568476E-3,0.00363234578008348,"HSPA1B/MYBL2/NEK6/AURKB/LIMK2/DLGAP5/KIFC1/NDC80/TUBB1/PLK1/EZR/SPAG5/BCCIP/BIRC5/MISP/WDR62",16]
[279,"up","up","GO:0120193","tight junction organization","10/604","82/18866",0.000282568730619234,4.90899870004095E-3,0.00371534437354472,"RAB13/GPBAR1/CLDN19/PARD6G/SNAI1/PARD3/CLDN23/CRB3/CLDN2/WNT11",10]
[280,"up","up","GO:0042269","regulation of natural killer cell mediated cytotoxicity","7/604","41/18866",0.000290321146872396,0.00502566642460894,3.80364359718158E-3,"LGALS9/MICA/LILRB1/HLA-B/HLA-A/NECTIN2/HLA-F",7]
[281,"up","up","GO:0007162","negative regulation of cell adhesion","22/604","301/18866",0.000295284889030207,0.00509340162679507,0.00385490855317577,"FOXJ1/IL1RN/MDK/THBS1/FAM107A/CD80/LGALS9/ARHGAP6/LGALS3/MMP14/GBP1/LILRB1/VSIG4/ERBB2/SERPINE1/HLX/CD300A/FGL1/BCL6/JAK3/ADAMDEC1/CEBPB",22]
[282,"up","up","GO:0002696","positive regulation of leukocyte activation","27/604","406/18866",0.000297417240118885,0.00510410304859795,0.0038630078560507,"IL1B/TNFSF14/MDK/CDKN1A/THBS1/IL6/CD80/CCL2/LGALS9/MMP14/LILRB1/ITGB2/CCL3/PNP/TNIP2/SPTA1/HLA-A/HLX/ITPKB/CD40/VNN1/BCL6/NECTIN2/JAK3/GLI2/HLA-F/ADA",27]
[283,"up","up","GO:0032623","interleukin-2 production","8/604","54/18866",0.000299004250089277,0.00510410304859795,0.0038630078560507,"IL1B/CD80/GBP1/TNFAIP3/EZR/VSIG4/SLC11A1/PNP",8]
[284,"up","up","GO:0045667","regulation of osteoblast differentiation","13/604","131/18866",0.000299064424551644,0.00510410304859795,0.0038630078560507,"SMAD1/IL6/CEBPD/SOX9/CLIC1/LTF/IGFBP5/GDPD2/LIMD1/TCIRG1/HGF/CEBPB/CCN1",13]
[285,"up","up","GO:0002718","regulation of cytokine production involved in immune response","10/604","83/18866",0.00031223485557342,5.31018366654164E-3,0.00401897865807339,"IL1B/HMOX1/IL6/BST2/LILRB1/TGFB2/HLA-A/BCL6/JAK3/HLA-F",10]
[286,"up","up","GO:0071824","protein-DNA complex subunit organization","21/604","282/18866",0.000313336132153673,0.0053102805333876,0.00401905197112827,"H3C13/H1-5/H1-2/H3C7/H2BC9/H2BC21/CENPA/H2BC18/DLGAP5/KNL1/SOX9/MYC/H2BC11/H4C15/CENPM/H2BC17/SMARCD3/H1-3/H2BC14/HJURP/H2BC3",21]
[287,"up","up","GO:0042129","regulation of T cell proliferation","15/604","167/18866",0.000316881172060729,0.00535164822640541,0.00405036084588902,"IL1B/FOXJ1/IL6/CD80/LGALS9/LGALS3/RAC2/LILRB1/VSIG4/PNP/SPTA1/ERBB2/HLA-A/JAK3/CEBPB",15]
[288,"up","up","GO:0010758","regulation of macrophage chemotaxis","6/604","30/18866",3.2357067189821E-4,0.00544080700403675,0.00411784009839359,"CYP19A1/MDK/THBS1/C5AR1/MSTN/CSF1",6]
[289,"up","up","GO:0050830","defense response to Gram-positive bacterium","11/604","99/18866",0.000325185567580865,0.00544080700403675,0.00411784009839359,"IL6/H2BC21/C5AR1/GBP2/MR1/H2BC11/GSDMD/LTA/TLR2/HLA-A/MYD88",11]
[290,"up","up","GO:0065004","protein-DNA complex assembly","19/604","243/18866",0.00032552796186727,0.00544080700403675,0.00411784009839359,"H3C13/H1-5/H1-2/H3C7/H2BC9/H2BC21/CENPA/H2BC18/DLGAP5/KNL1/SOX9/H2BC11/H4C15/CENPM/H2BC17/H1-3/H2BC14/HJURP/H2BC3",19]
[291,"up","up","GO:0045580","regulation of T cell differentiation","14/604","150/18866",0.000336089275623149,0.00557885177721029,0.00422231840499883,"IL1B/FOXJ1/MDK/CD80/LGALS9/PNP/ERBB2/HLX/ITPKB/VNN1/BCL6/JAK3/GLI2/ADA",14]
[292,"up","up","GO:0070665","positive regulation of leukocyte proliferation","14/604","150/18866",0.000336089275623149,0.00557885177721029,0.00422231840499883,"IL1B/CDKN1A/IL6/BST2/CD80/LGALS9/PNP/SPTA1/HLA-A/CSF1/CD40/BCL6/JAK3/ADA",14]
[293,"up","up","GO:0050854","regulation of antigen receptor-mediated signaling pathway","9/604","69/18866",0.000340325129590201,0.00562988362840855,4.26094153627394E-3,"LGALS3/GBP1/RELA/EZR/NFAM1/BLK/CD300A/NECTIN2/ADA",9]
[294,"up","up","GO:0002544","chronic inflammatory response","5/604","20/18866",0.00034391549798508,0.00566992659433225,4.29124779977803E-3,"CYP19A1/THBS1/LTA/TNFAIP3/VNN1",5]
[295,"up","up","GO:0061138","morphogenesis of a branching epithelium","16/604","187/18866",0.000351155500110398,0.00576966342045797,0.00436673298085545,"MDK/SMO/SOX9/SOCS3/MYC/ST14/MMP14/YAP1/ADM/SPINT1/VDR/PML/CSF1/HGF/WNT9B/GLI2",16]
[296,"up","up","GO:0045069","regulation of viral genome replication","11/604","100/18866",0.000355030191049354,0.00581361937843318,0.00440000076745021,"TOP2A/ISG15/ZC3HAV1/BST2/CXCL8/LTF/OAS3/IFI16/PLSCR1/IFITM3/OASL",11]
[297,"up","up","GO:0032102","negative regulation of response to external stimulus","28/604","433/18866",0.000363879270083156,0.005938460680448,0.00449448611107495,"PLAUR/CYP19A1/SPP1/MDK/THBS1/CLDN19/CCL2/LGALS9/SOCS3/MICA/LTF/TNFRSF1A/LILRB1/NMI/HLA-B/TNFAIP3/APOE/MICB/VSIG4/EPPK1/IFI16/SERPINE1/HLA-A/FPR2/GHSR/HGF/HLA-F/ADA",28]
[298,"up","up","GO:0051783","regulation of nuclear division","16/604","188/18866",0.000372729972427141,0.00604052115590255,0.00457172993133472,"IL1B/MKI67/HSPA1B/UBE2C/NEK6/AURKB/DLGAP5/NUSAP1/NDC80/PLK1/LIF/SPHK1/BUB1/BUB1B/NME6/CCDC8",16]
[299,"up","up","GO:0072676","lymphocyte migration","12/604","117/18866",3.73496139439059E-4,0.00604052115590255,0.00457172993133472,"ICAM1/TNFSF14/CCL4/HSD3B7/CCL2/CCL4L1/CXCL10/ITGAL/MYO1G/CCL3/MSN/SLC8B1",12]
[300,"up","up","GO:0045861","negative regulation of proteolysis","25/604","369/18866",0.000373871744743298,0.00604052115590255,0.00457172993133472,"SFN/PLAUR/IFI6/TNFSF14/SERPINA1/THBS1/BST2/CD44/SERPINH1/LTF/SERPINA5/SERPINA3/TIMP1/SPINT1/IFI16/C4B/CFLAR/BIRC5/SERPINE1/NGFR/TRIM21/PML/AMBP/ITIH1/HGF",25]
[301,"up","up","GO:0042742","defense response to bacterium","24/604","348/18866",0.000376461224385951,0.00605301614756412,0.00458118668612402,"JCHAIN/ISG15/IL6/H2BC21/C5AR1/GBP2/MR1/H2BC11/GSDMD/HAMP/MICA/LTF/TNFRSF1A/LTA/IRGM/SLC11A1/PPBP/TLR2/SERPINE1/HLA-A/NOTCH2/MYD88/FPR2/CEBPB",24]
[302,"up","up","GO:0051403","stress-activated MAPK cascade","21/604","286/18866",0.000378218468205779,0.00605301614756412,0.00458118668612402,"IL1B/GADD45G/LGALS9/MYC/MLKL/MID1/ERN2/NRK/ARHGEF5/LTBR/GADD45B/ZFP36L1/EZR/TNIP2/SPHK1/MDFIC/TGFB2/MAPKAPK2/IRAK2/AMBP/HGF",21]
[303,"up","up","GO:0043154","negative regulation of cysteine-type endopeptidase activity involved in apoptotic process","10/604","85/18866",0.000379403933470673,0.00605301614756412,0.00458118668612402,"SFN/PLAUR/IFI6/TNFSF14/THBS1/CD44/CFLAR/BIRC5/NGFR/HGF",10]
[304,"up","up","GO:0006879","cellular iron ion homeostasis","9/604","70/18866",3.79640377317824E-4,0.00605301614756412,0.00458118668612402,"HMOX1/FTL/MYC/HAMP/LTF/ALAS2/SLC11A1/ACO1/CP",9]
[305,"up","up","GO:0030071","regulation of mitotic metaphase/anaphase transition","8/604","56/18866",0.000385971087490284,6.09893518770473E-3,0.00461594021894193,"UBE2C/NEK6/AURKB/DLGAP5/NDC80/PLK1/BUB1/BUB1B",8]
[306,"up","up","GO:0090183","regulation of kidney development","8/604","56/18866",0.000385971087490284,6.09893518770473E-3,0.00461594021894193,"SMO/SOX9/MYC/YAP1/LIF/WWTR1/CFLAR/WNT9B",8]
[307,"up","up","GO:0032637","interleukin-8 production","11/604","101/18866",0.000387143015796999,6.09893518770473E-3,0.00461594021894193,"IL1B/HSPA1B/CD14/CHI3L1/IL6/TLR8/LGALS9/RELA/TLR2/SERPINE1/MYD88",11]
[308,"up","up","GO:0045088","regulation of innate immune response","22/604","307/18866",0.000387553546072428,6.09893518770473E-3,0.00461594021894193,"IRF7/TLR8/LGALS9/SOCS3/MICA/IRGM/RELA/LILRB1/NMI/HLA-B/TNFAIP3/TRIM5/APOE/VSIG4/IFI16/PLSCR1/HLA-A/PARP9/NECTIN2/FPR2/HCK/HLA-F",22]
[309,"up","up","GO:0050856","regulation of T cell receptor signaling pathway","7/604","43/18866",0.000393738796042513,0.0061762198848481,0.00467443264932093,"LGALS3/GBP1/RELA/EZR/CD300A/NECTIN2/ADA",7]
[310,"up","up","GO:0036293","response to decreased oxygen levels","25/604","371/18866",0.000405080174187929,0.00633362452996416,0.00479356335159569,"ICAM1/HMOX1/THBS1/HSD11B2/MYC/UCP2/MMP14/ALAS2/MGARP/ZFP36L1/LTA/EIF4EBP1/ADM/SOD3/SLC2A4/AGTRAP/TGFB2/CFLAR/STC1/TLR2/LIMD1/PML/PLOD1/ASCL2/ADA",25]
[311,"up","up","GO:0070664","negative regulation of leukocyte proliferation","10/604","86/18866",0.000417253410073095,0.0064946177777908,0.00491541006495628,"FOXJ1/CD80/LGALS9/LILRB1/TNFAIP3/VSIG4/ERBB2/BLK/CD300A/CEBPB",10]
[312,"up","up","GO:0043301","negative regulation of leukocyte degranulation","4/604","12/18866",0.000419396609129053,0.0064946177777908,0.00491541006495628,"HMOX1/LGALS9/CD300A/HLA-F",4]
[313,"up","up","GO:0060670","branching involved in labyrinthine layer morphogenesis","4/604","12/18866",0.000419396609129053,0.0064946177777908,0.00491541006495628,"SOCS3/ST14/ADM/SPINT1",4]
[314,"up","up","GO:0060760","positive regulation of response to cytokine stimulus","8/604","57/18866",0.00043659029708338,0.00669506728369215,0.00506711899572544,"HSPA1B/IRF7/CASP4/IFIH1/IRGM/TLR2/CSF1/PARP9",8]
[315,"up","up","GO:0061005","cell differentiation involved in kidney development","8/604","57/18866",0.00043659029708338,0.00669506728369215,0.00506711899572544,"FOXJ1/SMO/YAP1/LIF/WWTR1/KLF15/NOTCH2/WNT9B",8]
[316,"up","up","GO:0009110","vitamin biosynthetic process","5/604","21/18866",0.000439579513190119,0.00669506728369215,0.00506711899572544,"IL1B/SNAI1/PLTP/VDR/BCO1",5]
[317,"up","up","GO:0090280","positive regulation of calcium ion import","5/604","21/18866",0.000439579513190119,0.00669506728369215,0.00506711899572544,"CCL2/LGALS3/ATP2A1/CCL3/STC1",5]
[318,"up","up","GO:0002706","regulation of lymphocyte mediated immunity","14/604","154/18866",4.39685662094665E-4,0.00669506728369215,0.00506711899572544,"IL1B/FOXJ1/IL6/MR1/LGALS9/MICA/LTA/LILRB1/HLA-B/HLA-A/CD40/BCL6/NECTIN2/HLA-F",14]
[319,"up","up","GO:0031348","negative regulation of defense response","20/604","269/18866",0.00044062852558238,0.00669506728369215,0.00506711899572544,"CYP19A1/MDK/LGALS9/SOCS3/MICA/TNFRSF1A/LILRB1/NMI/HLA-B/TNFAIP3/APOE/MICB/VSIG4/IFI16/HLA-A/FPR2/GHSR/HGF/HLA-F/ADA",20]
[320,"up","up","GO:0032147","activation of protein kinase activity","23/604","331/18866",0.000445444562351643,6.74709310537004E-3,0.00510649440722196,"IL1B/GADD45G/CHI3L1/THBS1/GPRC5A/KIF14/C5AR1/FPR1/MLKL/ERN2/NRK/GADD45B/TNFRSF10B/MAPKAPK3/SLC11A1/MDFIC/TGFB2/MAPKAPK2/IRAK2/GDF15/CD300A/HGF/WNT11",23]
[321,"up","up","GO:0030198","extracellular matrix organization","26/604","395/18866",4.4689460464323E-4,6.74796931060977E-3,0.00510715755757225,"ICAM1/TNFRSF11B/SPP1/NFKB2/THBS1/IL6/CD44/MMP3/SERPINH1/SOX9/ITGAL/MMP14/NR2E1/TNFRSF1A/TIMP1/EMILIN1/ITGB2/SPINT1/TGFB2/CFLAR/ADAMTS2/MMP19/SERPINE1/MIA/LCP1/CCN1",26]
[322,"up","up","GO:0001913","T cell mediated cytotoxicity","7/604","44/18866",0.000455469678060095,0.006834865416586,0.00517292432145814,"MR1/MICA/LILRB1/HLA-B/HLA-A/NECTIN2/HLA-F",7]
[323,"up","up","GO:0033003","regulation of mast cell activation","7/604","44/18866",0.000455469678060095,0.006834865416586,0.00517292432145814,"HMOX1/LGALS9/RAC2/PLSCR1/BLK/CD300A/NECTIN2",7]
[324,"up","up","GO:0055072","iron ion homeostasis","10/604","87/18866",0.00045818976818291,0.00684122119055089,0.00517773464846836,"HMOX1/FTL/MYC/HAMP/LTF/ALAS2/SLC11A1/STEAP4/ACO1/CP",10]
[325,"up","up","GO:0008630","intrinsic apoptotic signaling pathway in response to DNA damage","11/604","103/18866",4.58716089731595E-4,0.00684122119055089,0.00517773464846836,"SFN/CDKN1A/HMOX1/BCL2A1/CD44/NUPR1/SNAI1/TNFRSF1A/HIC1/IFI16/PML",11]
[326,"up","up","GO:0032946","positive regulation of mononuclear cell proliferation","13/604","137/18866",0.000462467992219893,0.006860523142205,0.00519234320753682,"IL1B/CDKN1A/IL6/CD80/LGALS9/PNP/SPTA1/HLA-A/CSF1/CD40/BCL6/JAK3/ADA",13]
[327,"up","up","GO:0043062","extracellular structure organization","26/604","396/18866",0.000464256569144469,0.006860523142205,0.00519234320753682,"ICAM1/TNFRSF11B/SPP1/NFKB2/THBS1/IL6/CD44/MMP3/SERPINH1/SOX9/ITGAL/MMP14/NR2E1/TNFRSF1A/TIMP1/EMILIN1/ITGB2/SPINT1/TGFB2/CFLAR/ADAMTS2/MMP19/SERPINE1/MIA/LCP1/CCN1",26]
[328,"up","up","GO:0070482","response to oxygen levels","26/604","396/18866",0.000464256569144469,0.006860523142205,0.00519234320753682,"ICAM1/CDKN1A/HMOX1/THBS1/HSD11B2/MYC/UCP2/MMP14/ALAS2/MGARP/ZFP36L1/LTA/EIF4EBP1/ADM/SOD3/SLC2A4/AGTRAP/TGFB2/CFLAR/STC1/TLR2/LIMD1/PML/PLOD1/ASCL2/ADA",26]
[329,"up","up","GO:1901889","negative regulation of cell junction assembly","6/604","32/18866",4.67709032793293E-4,0.0068905339876872,5.21505672463486E-3,"IL1B/THBS1/FAM107A/ARHGAP6/MMP14/TLR2",6]
[330,"up","up","GO:0007091","metaphase/anaphase transition of mitotic cell cycle","8/604","58/18866",0.00049246767160216,0.00721145258083284,0.00545794191615051,"UBE2C/NEK6/AURKB/DLGAP5/NDC80/PLK1/BUB1/BUB1B",8]
[331,"up","up","GO:1902099","regulation of metaphase/anaphase transition of cell cycle","8/604","58/18866",0.00049246767160216,0.00721145258083284,0.00545794191615051,"UBE2C/NEK6/AURKB/DLGAP5/NDC80/PLK1/BUB1/BUB1B",8]
[332,"up","up","GO:0070098","chemokine-mediated signaling pathway","10/604","88/18866",0.000502405284071328,0.0073348144936558,0.00555130759349581,"CCL4/CXCL1/CXCL5/CCL2/CXCL8/CXCL3/CCL4L1/CXCL10/CCL3/PPBP",10]
[333,"up","up","GO:0002715","regulation of natural killer cell mediated immunity","7/604","45/18866",0.000524680392131953,0.00761414928342387,5.76272034850254E-3,"LGALS9/MICA/LILRB1/HLA-B/HLA-A/NECTIN2/HLA-F",7]
[334,"up","up","GO:0006775","fat-soluble vitamin metabolic process","7/604","45/18866",0.000524680392131953,0.00761414928342387,5.76272034850254E-3,"IL1B/SNAI1/PLTP/CYP11A1/CYP4F11/VDR/BCO1",7]
[335,"up","up","GO:0009266","response to temperature stimulus","18/604","233/18866",0.000534280801790355,0.00773032551127716,0.00585064758598393,"HSPA1B/CD14/CDKN1A/PIRT/HMOX1/THBS1/BAG3/ZNF516/UCP2/MICA/CXCL10/ADM/MICB/MAPKAPK2/MSTN/NGFR/DNAJB1/CHORDC1",18]
[336,"up","up","GO:0030217","T cell differentiation","19/604","253/18866",0.000536881952115639,0.00774484173185863,0.00586163409499687,"IL1B/FOXJ1/MDK/BATF/IL6/CD80/MR1/LGALS9/ZFP36L1/PNP/ERBB2/HLX/ITPKB/VNN1/BCL6/TCIRG1/JAK3/GLI2/ADA",19]
[337,"up","up","GO:0021782","glial cell development","12/604","122/18866",0.000547563916821586,0.00787549645351403,0.00596051928821873,"IL1B/BACE2/MDK/IL6/C5AR1/SMO/VIM/PARD3/C1QA/TLR2/LGI4/FPR2",12]
[338,"up","up","GO:0006925","inflammatory cell apoptotic process","5/604","22/18866",0.000553996500220706,0.00792106716015493,0.00599500918704786,"IL6/IRF7/ITPKB/HCAR2/GHSR",5]
[339,"up","up","GO:0071385","cellular response to glucocorticoid stimulus","8/604","59/18866",0.000554000777242113,0.00792106716015493,0.00599500918704786,"NPAS4/ICAM1/FAM107A/ZFP36L1/EIF4EBP1/CFLAR/STC1/MSTN",8]
[340,"up","up","GO:0033028","myeloid cell apoptotic process","6/604","33/18866",0.000556341324631282,0.00793113647202301,0.00600263008154804,"IL6/IRF7/ITPKB/HCAR2/GHSR/CLEC5A",6]
[341,"up","up","GO:0045926","negative regulation of growth","19/604","254/18866",5.63420584252058E-4,0.00798508646745534,0.00604346179168489,"HSPA1B/SPP1/CDKN1A/BST2/OSGIN1/IGFBP5/CDKN2C/TGFB2/MSTN/MT2A/PML/GDF15/NOTCH2/NME6/BDKRB1/BCL6/MT1X/WNT11/BTG1",19]
[342,"up","up","GO:2000027","regulation of animal organ morphogenesis","19/604","254/18866",5.63420584252058E-4,0.00798508646745534,0.00604346179168489,"PLEKHA4/TNFRSF11B/MDK/SMO/SOX9/PIM1/MYC/TNFAIP3/LIF/TGFB2/CFLAR/VDR/GRHL3/NGFR/CSF1/HGF/ZNRF3/WNT9B/WNT11",19]
[343,"up","up","GO:0032481","positive regulation of type I interferon production","9/604","74/18866",0.000576204330925833,8.14245595334551E-3,6.16256588392366E-3,"CD14/NFKB2/IRF7/TLR8/IFIH1/RELA/IFI16/TLR2/MYD88",9]
[344,"up","up","GO:0031589","cell-substrate adhesion","24/604","359/18866",0.000587608948206253,0.0082011563989636,0.00620699294200171,"MDK/THBS1/SIGLEC1/FAM107A/CD44/KIF14/FERMT3/PARVG/RREB1/ARHGAP6/ITGAL/MMP14/MYO1G/GBP1/RAC2/EMILIN1/ITGB2/TNFRSF12A/RHOD/SERPINE1/CSF1/CARMIL1/BCL6/CCN1",24]
[345,"up","up","GO:0002761","regulation of myeloid leukocyte differentiation","12/604","123/18866",0.000589509615240279,0.0082011563989636,0.00620699294200171,"IRF7/C1QC/MYC/LTF/HCLS1/ZFP36L1/LILRB1/LIF/CCL3/NOTCH2/CSF1/CEBPB",12]
[346,"up","up","GO:0000819","sister chromatid segregation","16/604","196/18866",0.000590363549637124,0.0082011563989636,0.00620699294200171,"TOP2A/UBE2C/KIF14/NEK6/AURKB/DLGAP5/KIFC1/NUSAP1/NDC80/KIF18B/PLK1/SPAG5/KIF18A/BUB1/BUB1B/NCAPG",16]
[347,"up","up","GO:0060759","regulation of response to cytokine stimulus","16/604","196/18866",0.000590363549637124,0.0082011563989636,0.00620699294200171,"HSPA1B/IL1RN/IL6/IRF7/CASP4/SOCS3/H2BC11/IFIH1/TNFRSF1A/IRGM/TNFAIP3/SPHK1/TLR2/IRAK2/CSF1/PARP9",16]
[348,"up","up","GO:0030656","regulation of vitamin metabolic process","4/604","13/18866",0.000590510332832329,0.0082011563989636,0.00620699294200171,"IL1B/AKR1C3/SNAI1/VDR",4]
[349,"up","up","GO:0033089","positive regulation of T cell differentiation in thymus","4/604","13/18866",0.000590510332832329,0.0082011563989636,0.00620699294200171,"IL1B/VNN1/GLI2/ADA",4]
[350,"up","up","GO:0046427","positive regulation of receptor signaling pathway via JAK-STAT","10/604","90/18866",0.000601481858565894,0.00831316848417306,0.00629176857466759,"IL6/OSM/SOCS3/HCLS1/TNFRSF1A/LIF/IL10RA/CD40/CD300A/PARP9",10]
[351,"up","up","GO:0032570","response to progesterone","7/604","46/18866",0.000602005805228955,0.00831316848417306,0.00629176857466759,"FOSL1/THBS1/FOSB/YAP1/RELA/TGFB2/TLR2",7]
[352,"up","up","GO:0032732","positive regulation of interleukin-1 production","8/604","60/18866",6.21604680680013E-4,0.00853517815086693,0.00645979517569658,"HSPB1/IL6/TLR8/LGALS9/ORM2/GSDMD/CCL3/IFI16",8]
[353,"up","up","GO:0044784","metaphase/anaphase transition of cell cycle","8/604","60/18866",6.21604680680013E-4,0.00853517815086693,0.00645979517569658,"UBE2C/NEK6/AURKB/DLGAP5/NDC80/PLK1/BUB1/BUB1B",8]
[354,"up","up","GO:0030330","DNA damage response, signal transduction by p53 class mediator","11/604","107/18866",0.000635358829863447,0.00864232763596281,6.54089058046331E-3,"SFN/CDKN1A/BATF/CD44/SNAI1/E2F7/HIC1/PTTG1IP/CDK2/DYRK3/PML",11]
[355,"up","up","GO:0001910","regulation of leukocyte mediated cytotoxicity","9/604","75/18866",0.000636540327220698,0.00864232763596281,6.54089058046331E-3,"ICAM1/MR1/LGALS9/MICA/LILRB1/HLA-B/HLA-A/NECTIN2/HLA-F",9]
[356,"up","up","GO:0031100","animal organ regeneration","9/604","75/18866",0.000636540327220698,0.00864232763596281,6.54089058046331E-3,"CDKN1A/HMOX1/IL6/C5AR1/HAMP/ADM/LCP1/HGF/CEBPB",9]
[357,"up","up","GO:0061844","antimicrobial humoral immune response mediated by antimicrobial peptide","9/604","75/18866",0.000636540327220698,0.00864232763596281,6.54089058046331E-3,"CXCL1/CXCL5/H2BC21/CXCL8/CXCL3/H2BC11/CXCL10/LTF/PPBP",9]
[358,"up","up","GO:0072073","kidney epithelium development","13/604","142/18866",0.000651317260582844,0.00881825352526548,6.6740389683364E-3,"FOXJ1/SMAD1/SMO/SOX9/SDC1/MYC/YAP1/LIF/WWTR1/KLF15/NOTCH2/WNT9B/WNT11",13]
[359,"up","up","GO:0033273","response to vitamin","10/604","91/18866",0.000656766663924777,0.00882776903844634,6.68124072383036E-3,"SPP1/TRIM25/PIM1/HAMP/CXCL10/RELA/VDR/STC1/CD40/ADA",10]
[360,"up","up","GO:0042475","odontogenesis of dentin-containing tooth","10/604","91/18866",0.000656766663924777,0.00882776903844634,6.68124072383036E-3,"TNFRSF11B/SMO/ADM/HDAC1/FST/SERPINE1/NGFR/CSF1/TCIRG1/GLI2",10]
[361,"up","up","GO:0048566","embryonic digestive tract development","6/604","34/18866",0.000657483932923278,0.00882776903844634,6.68124072383036E-3,"CXCL8/PCSK5/TGFB2/HLX/GLI2/ADA",6]
[362,"up","up","GO:0030261","chromosome condensation","7/604","47/18866",0.000688109214011989,0.00911382622475658,0.00689774128180788,"H1-5/H1-2/TOP2A/ERN2/NUSAP1/H1-3/NCAPG",7]
[363,"up","up","GO:0043300","regulation of leukocyte degranulation","7/604","47/18866",0.000688109214011989,0.00911382622475658,0.00689774128180788,"HMOX1/LGALS9/RAC2/ITGB2/BLK/CD300A/HLA-F",7]
[364,"up","up","GO:0003283","atrial septum development","5/604","23/18866",0.00068939425259755,0.00911382622475658,0.00689774128180788,"SMO/TGFB2/NOTCH2/WNT11/CCN1",5]
[365,"up","up","GO:0072170","metanephric tubule development","5/604","23/18866",0.00068939425259755,0.00911382622475658,0.00689774128180788,"SOX9/YAP1/LIF/WWTR1/WNT9B",5]
[366,"up","up","GO:0072215","regulation of metanephros development","5/604","23/18866",0.00068939425259755,0.00911382622475658,0.00689774128180788,"MYC/YAP1/LIF/WWTR1/WNT9B",5]
[367,"up","up","GO:0031349","positive regulation of defense response","25/604","385/18866",0.000695216690182783,0.00911382622475658,0.00689774128180788,"IL1B/MDK/IL6/IRF7/TLR8/OSM/NUPR1/TNFRSF1A/LTA/IRGM/RELA/TRIM5/CCL3/IFI16/PLSCR1/TLR2/SERPINE1/C2CD4B/MYD88/PARP9/NECTIN2/FPR2/HCK/CEBPB/HLA-F",25]
[368,"up","up","GO:0003170","heart valve development","8/604","61/18866",0.000695711925553937,0.00911382622475658,0.00689774128180788,"SOX9/SNAI1/TNFRSF1A/EMILIN1/TGFB2/NOTCH2/NFATC1/CCN1",8]
[369,"up","up","GO:0010965","regulation of mitotic sister chromatid separation","8/604","61/18866",0.000695711925553937,0.00911382622475658,0.00689774128180788,"UBE2C/NEK6/AURKB/DLGAP5/NDC80/PLK1/BUB1/BUB1B",8]
[370,"up","up","GO:0045576","mast cell activation","8/604","61/18866",0.000695711925553937,0.00911382622475658,0.00689774128180788,"HMOX1/LGALS9/RAC2/PLSCR1/BLK/CD300A/NECTIN2/LCP2",8]
[371,"up","up","GO:0033077","T cell differentiation in thymus","9/604","76/18866",0.000701942019316553,0.00917065489926505,0.00694075170185328,"IL1B/FOXJ1/MR1/ZFP36L1/ERBB2/ITPKB/VNN1/GLI2/ADA",9]
[372,"up","up","GO:0031098","stress-activated protein kinase signaling cascade","21/604","300/18866",0.000706635532650713,0.00920715706117744,0.00696837813041238,"IL1B/GADD45G/LGALS9/MYC/MLKL/MID1/ERN2/NRK/ARHGEF5/LTBR/GADD45B/ZFP36L1/EZR/TNIP2/SPHK1/MDFIC/TGFB2/MAPKAPK2/IRAK2/AMBP/HGF",21]
[373,"up","up","GO:2000116","regulation of cysteine-type endopeptidase activity","18/604","239/18866",0.000720064249918872,0.00935697431462942,7.08176636367227E-3,"SFN/PLAUR/IFI6/TNFSF14/THBS1/CD44/LGALS9/MYC/SOX2/LTF/TNFRSF10B/IFI16/CFLAR/BIRC5/NGFR/PML/HGF/CCN1",18]
[374,"up","up","GO:0007596","blood coagulation","23/604","343/18866",0.000727709441355213,9.43103653007679E-3,0.00713781987932147,"H3C13/PLAUR/HSPB1/H3C7/SERPINA1/THBS1/IL6/FERMT3/MAFF/SLC4A1/CLIC1/SERPINA5/CYP4F11/APOE/PLEK/PLSCR1/HDAC1/SERPINE1/HMG20B/BLK/CD40/CARMIL1/LCP2",23]
[375,"up","up","GO:1902850","microtubule cytoskeleton organization involved in mitosis","13/604","144/18866",0.000743226363180291,0.00960644848622632,7.27057930016369E-3,"HSPA1B/MYBL2/CENPA/AURKB/DLGAP5/KIFC1/NUSAP1/NDC80/PLK1/BCCIP/BIRC5/MISP/WDR62",13]
[376,"up","up","GO:0048285","organelle fission","29/604","476/18866",0.000751106603913028,0.0096824832690597,0.00732812574086479,"IL1B/MKI67/HSPA1B/TOP2A/MYBL2/UBE2C/KIF14/NEK6/AURKB/DLGAP5/KIFC1/NUSAP1/NDC80/KIF18B/PLK1/LIF/SPAG5/SPHK1/BCCIP/KIF18A/CCNB2/BUB1/BIRC5/BUB1B/MISP/NME6/CCDC8/TEX19/NCAPG",29]
[377,"up","up","GO:0001914","regulation of T cell mediated cytotoxicity","6/604","35/18866",0.000772299446623864,0.00981924741757803,0.00743163481486311,"MR1/LILRB1/HLA-B/HLA-A/NECTIN2/HLA-F",6]
[378,"up","up","GO:0040001","establishment of mitotic spindle localization","6/604","35/18866",0.000772299446623864,0.00981924741757803,0.00743163481486311,"CENPA/NUSAP1/NDC80/PLK1/BCCIP/MISP",6]
[379,"up","up","GO:0060674","placenta blood vessel development","6/604","35/18866",0.000772299446623864,0.00981924741757803,0.00743163481486311,"FOSL1/PLCD1/SOCS3/SPINT1/NOTCH2/CCN1",6]
[380,"up","up","GO:0001763","morphogenesis of a branching structure","16/604","201/18866",0.000775479337279084,0.00981924741757803,0.00743163481486311,"MDK/SMO/SOX9/SOCS3/MYC/ST14/MMP14/YAP1/ADM/SPINT1/VDR/PML/CSF1/HGF/WNT9B/GLI2",16]
[381,"up","up","GO:0031099","regeneration","16/604","201/18866",0.000775479337279084,0.00981924741757803,0.00743163481486311,"SPP1/MDK/CDKN1A/HMOX1/IL6/C5AR1/HAMP/SOX2/YAP1/ADM/EPPK1/CFLAR/MSTN/LCP1/HGF/CEBPB",16]
[382,"up","up","GO:0002260","lymphocyte homeostasis","8/604","62/18866",0.000776772467112496,0.00981924741757803,0.00743163481486311,"TNFSF14/LGALS9/TNFAIP3/CCNB2/SPTA1/TCIRG1/JAK3/ADA",8]
[383,"up","up","GO:2000351","regulation of endothelial cell apoptotic process","8/604","62/18866",0.000776772467112496,0.00981924741757803,0.00743163481486311,"ICAM1/THBS1/AKR1C3/CCL2/TNFAIP3/TNIP2/SERPINE1/CD40",8]
[384,"up","up","GO:0032677","regulation of interleukin-8 production","10/604","93/18866",0.000779948474472363,0.00981924741757803,0.00743163481486311,"IL1B/HSPA1B/CD14/IL6/TLR8/LGALS9/RELA/TLR2/SERPINE1/MYD88",10]
[385,"up","up","GO:1904894","positive regulation of receptor signaling pathway via STAT","10/604","93/18866",0.000779948474472363,0.00981924741757803,0.00743163481486311,"IL6/OSM/SOCS3/HCLS1/TNFRSF1A/LIF/IL10RA/CD40/CD300A/PARP9",10]
[386,"up","up","GO:0072009","nephron epithelium development","11/604","110/18866",0.000802214746301622,0.0100413733066468,0.00759974937805568,"FOXJ1/SMO/SOX9/MYC/YAP1/LIF/WWTR1/KLF15/NOTCH2/WNT9B/WNT11",11]
[387,"up","up","GO:0060707","trophoblast giant cell differentiation","4/604","14/18866",0.000805878732470725,0.0100413733066468,0.00759974937805568,"SOCS3/SNAI1/E2F7/LIF",4]
[388,"up","up","GO:0070431","nucleotide-binding oligomerization domain containing 2 signaling pathway","4/604","14/18866",0.000805878732470725,0.0100413733066468,0.00759974937805568,"HSPA1B/IRGM/RELA/TNFAIP3",4]
[389,"up","up","GO:0070486","leukocyte aggregation","4/604","14/18866",0.000805878732470725,0.0100413733066468,0.00759974937805568,"IL1B/CD44/RAC2/MSN",4]
[390,"up","up","GO:0051591","response to cAMP","10/604","94/18866",0.000848317268334111,0.0105160966742083,0.00795904073265413,"FOSL1/FOSB/SDC1/IGFBP5/ZFP36L1/AGXT/RELA/EZR/STC1/MMP19",10]
[391,"up","up","GO:1905954","positive regulation of lipid localization","10/604","94/18866",0.000848317268334111,0.0105160966742083,0.00795904073265413,"IL1B/CYP19A1/SPP1/MSR1/ABCA1/PLTP/APOE/PLIN2/PLIN5/ABCB4",10]
[392,"up","up","GO:0032652","regulation of interleukin-1 production","11/604","111/18866",0.000865315163534689,0.0106451334965803,0.00805670142911673,"HSPB1/IL6/TLR8/LGALS9/ORM2/GSDMD/TNFAIP3/CCL3/IFI16/SPHK1/GHSR",11]
[393,"up","up","GO:0042303","molting cycle","11/604","111/18866",0.000865315163534689,0.0106451334965803,0.00805670142911673,"LHX2/SMO/SOX9/SNAI1/IGFBP5/RELA/HDAC1/TGFB2/FST/NGFR/GLI2",11]
[394,"up","up","GO:0042633","hair cycle","11/604","111/18866",0.000865315163534689,0.0106451334965803,0.00805670142911673,"LHX2/SMO/SOX9/SNAI1/IGFBP5/RELA/HDAC1/TGFB2/FST/NGFR/GLI2",11]
[395,"up","up","GO:0008406","gonad development","17/604","223/18866",0.000875208988733192,0.0107395897933918,0.00812819007524363,"RAB13/ICAM1/CYP19A1/AKR1C3/NUPR1/SOX9/SDC1/MMP14/LHCGR/MGST1/TGFB2/KIF18A/FST/MMP19/TEX19/FANCG/CEBPB",17]
[396,"up","up","GO:0007599","hemostasis","23/604","348/18866",0.000884927846641105,0.0108314274562359,0.00819769682494484,"H3C13/PLAUR/HSPB1/H3C7/SERPINA1/THBS1/IL6/FERMT3/MAFF/SLC4A1/CLIC1/SERPINA5/CYP4F11/APOE/PLEK/PLSCR1/HDAC1/SERPINE1/HMG20B/BLK/CD40/CARMIL1/LCP2",23]
[397,"up","up","GO:0060711","labyrinthine layer development","7/604","49/18866",0.000889442665843152,0.010859265998342,0.00821876624808003,"PLCD1/SOCS3/ST14/ZFP36L1/ADM/SPINT1/CCN1",7]
[398,"up","up","GO:0007043","cell-cell junction assembly","13/604","147/18866",0.000901396727874193,0.0108755719741506,0.00823110732192781,"IL1B/RAB13/CDHR3/GPBAR1/CLDN19/PARD6G/SNAI1/PARD3/CLDN23/RHOC/CRB3/CLDN2/WNT11",13]
[399,"up","up","GO:0034101","erythrocyte homeostasis","12/604","129/18866",0.000901902887796536,0.0108755719741506,0.00823110732192781,"HSPA1B/SPI1/ISG15/HMOX1/SLC4A1/HCLS1/ALAS2/ZFP36L1/ETV2/DYRK3/BCL6/JAK3",12]
[400,"up","up","GO:0003230","cardiac atrium development","6/604","36/18866",0.000901997097918,0.0108755719741506,0.00823110732192781,"MYH6/SMO/TGFB2/NOTCH2/WNT11/CCN1",6]
[401,"up","up","GO:0009595","detection of biotic stimulus","6/604","36/18866",0.000901997097918,0.0108755719741506,0.00823110732192781,"SMO/YAP1/HLA-B/C4B/TLR2/HLA-A",6]
[402,"up","up","GO:0033280","response to vitamin D","6/604","36/18866",0.000901997097918,0.0108755719741506,0.00823110732192781,"SPP1/TRIM25/PIM1/CXCL10/VDR/STC1",6]
[403,"up","up","GO:0070372","regulation of ERK1 and ERK2 cascade","21/604","306/18866",0.000909837715264864,0.0109428868632476,0.00828205416663981,"IL1B/ICAM1/CCL4/CHI3L1/CD44/C5AR1/GPBAR1/CCL2/LGALS9/CCL4L1/GBP1/EMILIN1/LIF/EZR/APOE/CCL3/CFLAR/ERBB2/NOTCH2/FPR2/CCN1",21]
[404,"up","up","GO:0050817","coagulation","23/604","349/18866",0.000919675734697954,0.0110338323912896,0.00835088570980295,"H3C13/PLAUR/HSPB1/H3C7/SERPINA1/THBS1/IL6/FERMT3/MAFF/SLC4A1/CLIC1/SERPINA5/CYP4F11/APOE/PLEK/PLSCR1/HDAC1/SERPINE1/HMG20B/BLK/CD40/CARMIL1/LCP2",23]
[405,"up","up","GO:0007093","mitotic cell cycle checkpoint","14/604","166/18866",0.000927788167756979,0.0110763281997982,0.00838304839158173,"SFN/TOP2A/CDKN1A/AURKB/WEE1/NDC80/NABP1/E2F7/PLK1/CDK2/BUB1/BUB1B/PLK5/PML",14]
[406,"up","up","GO:0009408","response to heat","14/604","166/18866",0.000927788167756979,0.0110763281997982,0.00838304839158173,"HSPA1B/CD14/CDKN1A/PIRT/HMOX1/THBS1/BAG3/MICA/CXCL10/MICB/MAPKAPK2/MSTN/DNAJB1/CHORDC1",14]
[407,"up","up","GO:0050672","negative regulation of lymphocyte proliferation","9/604","79/18866",0.000931738722901768,0.0110961611545574,0.00839805883696537,"FOXJ1/CD80/LGALS9/LILRB1/VSIG4/ERBB2/BLK/CD300A/CEBPB",9]
[408,"up","up","GO:0046637","regulation of alpha-beta T cell differentiation","8/604","64/18866",0.000961639634797501,0.0113962525913533,8.62518112796112E-3,"CD80/LGALS9/PNP/HLX/ITPKB/BCL6/JAK3/ADA",8]
[409,"up","up","GO:0051306","mitotic sister chromatid separation","8/604","64/18866",0.000961639634797501,0.0113962525913533,8.62518112796112E-3,"UBE2C/NEK6/AURKB/DLGAP5/NDC80/PLK1/BUB1/BUB1B",8]
[410,"up","up","GO:0002711","positive regulation of T cell mediated immunity","7/604","50/18866",0.00100613710191144,0.0118945037389384,0.00900227933289184,"IL1B/IL6/MR1/HLA-B/HLA-A/NECTIN2/HLA-F",7]
[411,"up","up","GO:0044706","multi-multicellular organism process","17/604","226/18866",0.00101452147836586,0.0119387417864241,0.00903576061713438,"IL1B/SPP1/FOSL1/HSD11B2/MAFF/FOSB/LGALS9/NRK/PCSK5/IGFBP5/TIMP1/LIF/ADM/VDR/STC1/AMBP/GHSR",17]
[412,"up","up","GO:0071375","cellular response to peptide hormone stimulus","22/604","330/18866",0.00101480536744516,0.0119387417864241,0.00903576061713438,"IL1B/RAB13/SOCS3/MGARP/CYFIP1/ZFP36L1/RELA/CYP11A1/EIF4EBP1/LHCGR/SLC2A4/ATP6V0E1/BCAR3/AGTRAP/CFLAR/MSTN/GDF15/MZB1/TCIRG1/JAK3/GHSR/LPIN3",22]
[413,"up","up","GO:0032945","negative regulation of mononuclear cell proliferation","9/604","80/18866",1.02065825888201E-3,0.0119495907748818,0.00904397160489141,"FOXJ1/CD80/LGALS9/LILRB1/VSIG4/ERBB2/BLK/CD300A/CEBPB",9]
[414,"up","up","GO:1901224","positive regulation of NIK/NF-kappaB signaling","9/604","80/18866",1.02065825888201E-3,0.0119495907748818,0.00904397160489141,"IL1B/TNFSF14/CD14/CHI3L1/LGALS9/TNFRSF10B/RELA/SPHK1/TLR2",9]
[415,"up","up","GO:0034162","toll-like receptor 9 signaling pathway","5/604","25/18866",0.00103246327142773,0.0120296862418515,0.00910459134849608,"TLR8/PIK3AP1/TNIP2/IRAK2/MYD88",5]
[416,"up","up","GO:0046697","decidualization","5/604","25/18866",0.00103246327142773,0.0120296862418515,0.00910459134849608,"SPP1/LIF/VDR/STC1/GHSR",5]
[417,"up","up","GO:0018108","peptidyl-tyrosine phosphorylation","24/604","374/18866",0.00103805501756939,0.0120658337413881,0.00913194935309685,"ICAM1/IL6/GPRC5A/CD44/CD80/OSM/CSF3/SOCS3/WEE1/HCLS1/TNFRSF1A/EHD4/LIF/ITGB2/MELK/ERBB2/DYRK3/BLK/CD40/CD300A/PARP9/JAK3/HGF/HCK",24]
[418,"up","up","GO:1904994","regulation of leukocyte adhesion to vascular endothelial cell","6/604","37/18866",0.00104783046749334,0.0121503212343067,0.00919589317354388,"SELE/ICAM1/MDK/IL6/RELA/ITGB2",6]
[419,"up","up","GO:0048247","lymphocyte chemotaxis","8/604","65/18866",0.00106643205728754,0.0122174058951845,0.0092466657714958,"TNFSF14/CCL4/HSD3B7/CCL2/CCL4L1/CXCL10/CCL3/SLC8B1",8]
[420,"up","up","GO:0090307","mitotic spindle assembly","8/604","65/18866",0.00106643205728754,0.0122174058951845,0.0092466657714958,"HSPA1B/MYBL2/AURKB/KIFC1/PLK1/BCCIP/BIRC5/MISP",8]
[421,"up","up","GO:0034134","toll-like receptor 2 signaling pathway","4/604","15/18866",1.07126005889281E-3,0.0122174058951845,0.0092466657714958,"PIK3AP1/TNFAIP3/TNIP2/TLR2",4]
[422,"up","up","GO:0043518","negative regulation of DNA damage response, signal transduction by p53 class mediator","4/604","15/18866",1.07126005889281E-3,0.0122174058951845,0.0092466657714958,"CD44/SNAI1/PTTG1IP/DYRK3",4]
[423,"up","up","GO:0060009","Sertoli cell development","4/604","15/18866",1.07126005889281E-3,0.0122174058951845,0.0092466657714958,"RAB13/ICAM1/SOX9/SDC1",4]
[424,"up","up","GO:0071801","regulation of podosome assembly","4/604","15/18866",1.07126005889281E-3,0.0122174058951845,0.0092466657714958,"ARHGEF5/MSN/LCP1/HCK",4]
[425,"up","up","GO:1902187","negative regulation of viral release from host cell","4/604","15/18866",1.07126005889281E-3,0.0122174058951845,0.0092466657714958,"TRIM25/TRIM5/TRIM21/PML",4]
[426,"up","up","GO:0050764","regulation of phagocytosis","10/604","97/18866",1.0835359442513E-3,0.0122707914060422,0.00928707025508063,"IL1B/CCL2/C2/SLC11A1/SPHK1/C4B/TLR2/CD300A/FPR2/HCK",10]
[427,"up","up","GO:1990868","response to chemokine","10/604","97/18866",1.0835359442513E-3,0.0122707914060422,0.00928707025508063,"CCL4/CXCL1/CXCL5/CCL2/CXCL8/CXCL3/CCL4L1/CXCL10/CCL3/PPBP",10]
[428,"up","up","GO:1990869","cellular response to chemokine","10/604","97/18866",1.0835359442513E-3,0.0122707914060422,0.00928707025508063,"CCL4/CXCL1/CXCL5/CCL2/CXCL8/CXCL3/CCL4L1/CXCL10/CCL3/PPBP",10]
[429,"up","up","GO:0001558","regulation of cell growth","26/604","420/18866",0.00110176411154695,0.0124404694687407,0.00941549001521533,"SFN/HSPA1B/H1-5/SPP1/CDKN1A/FAM107A/BST2/KIF14/OSGIN1/HAMP/CISH/MMP14/CYFIP1/IGFBP5/CDKN2C/APOE/TNFRSF12A/SPHK1/TGFB2/ERBB2/PML/NME6/BDKRB1/BCL6/WNT11/BTG1",26]
[430,"up","up","GO:0042476","odontogenesis","12/604","132/18866",0.00110365212947359,0.0124404694687407,0.00941549001521533,"TNFRSF11B/SMO/SDC1/ADM/HDAC1/TGFB2/FST/SERPINE1/NGFR/CSF1/TCIRG1/GLI2",12]
[431,"up","up","GO:1902905","positive regulation of supramolecular fiber organization","16/604","208/18866",0.00111615815232039,0.0125522472489488,0.0095000883156345,"HSPA1B/SCIN/ICAM1/CSF3/VASP/ARHGEF5/ACTR3C/CYFIP1/GPR65/APOE/PLEK/RHOC/FHOD1/CARMIL1/HCK/WNT11",16]
[432,"up","up","GO:1902893","regulation of pri-miRNA transcription by RNA polymerase II","7/604","51/18866",0.00113453700882868,0.0127294001893347,0.0096341653892981,"SPI1/FOSL1/SMAD1/SOX9/RELA/TGFB2/NGFR",7]
[433,"up","up","GO:0071103","DNA conformation change","23/604","355/18866",1.15398012002606E-3,0.0128986785065735,0.00976228260462983,"H3C13/H1-5/H1-2/H3C7/TOP2A/H2BC9/H2BC21/CENPA/H2BC18/KNL1/SOX9/H2BC11/H4C15/CENPM/ERN2/NUSAP1/H2BC17/HDAC1/H1-3/H2BC14/HJURP/H2BC3/NCAPG",23]
[434,"up","up","GO:0018212","peptidyl-tyrosine modification","24/604","377/18866",0.00115739188804864,0.0128986785065735,0.00976228260462983,"ICAM1/IL6/GPRC5A/CD44/CD80/OSM/CSF3/SOCS3/WEE1/HCLS1/TNFRSF1A/EHD4/LIF/ITGB2/MELK/ERBB2/DYRK3/BLK/CD40/CD300A/PARP9/JAK3/HGF/HCK",24]
[435,"up","up","GO:0032609","interferon-gamma production","11/604","115/18866",0.00116026899708398,0.0128986785065735,0.00976228260462983,"IL1B/CD14/ISG15/TLR8/BTN3A1/LGALS9/BTN3A2/LTA/LILRB1/SLC11A1/HLA-A",11]
[436,"up","up","GO:0051225","spindle assembly","11/604","115/18866",0.00116026899708398,0.0128986785065735,0.00976228260462983,"HSPA1B/MYBL2/NEK6/AURKB/KIFC1/TUBB1/PLK1/SPAG5/BCCIP/BIRC5/MISP",11]
[437,"up","up","GO:0045137","development of primary sexual characteristics","17/604","229/18866",1.1722674972266E-3,0.0130022438422364,9.84066536874551E-3,"RAB13/ICAM1/CYP19A1/AKR1C3/NUPR1/SOX9/SDC1/MMP14/LHCGR/MGST1/TGFB2/KIF18A/FST/MMP19/TEX19/FANCG/CEBPB",17]
[438,"up","up","GO:0042770","signal transduction in response to DNA damage","12/604","133/18866",1.17869832273583E-3,0.0130300272244557,0.00986169304447204,"SFN/CDKN1A/BATF/CD44/SNAI1/E2F7/PLK1/HIC1/PTTG1IP/CDK2/DYRK3/PML",12]
[439,"up","up","GO:1905818","regulation of chromosome separation","8/604","66/18866",1.18014894811967E-3,0.0130300272244557,0.00986169304447204,"UBE2C/NEK6/AURKB/DLGAP5/NDC80/PLK1/BUB1/BUB1B",8]
[440,"up","up","GO:0007059","chromosome segregation","22/604","334/18866",0.00118543012449923,0.0130585904851085,0.00988331096621963,"MKI67/TOP2A/UBE2C/GEM/KIF14/NEK6/AURKB/DLGAP5/KNL1/KIFC1/NUSAP1/CDCA2/NDC80/KIF18B/PLK1/SPAG5/KIF18A/BUB1/BIRC5/BUB1B/HJURP/NCAPG",22]
[441,"up","up","GO:0030224","monocyte differentiation","6/604","38/18866",1.21109501610673E-3,0.0132809446675777,0.010051598311817,"IRF7/MYC/ZFP36L1/PIR/IFI16/CSF1",6]
[442,"up","up","GO:1903131","mononuclear cell differentiation","6/604","38/18866",1.21109501610673E-3,0.0132809446675777,0.010051598311817,"IRF7/MYC/ZFP36L1/PIR/IFI16/CSF1",6]
[443,"up","up","GO:0051495","positive regulation of cytoskeleton organization","17/604","230/18866",1.22927094888239E-3,0.0133579563510195,0.0101098841135164,"HSPA1B/SCIN/ICAM1/CSF3/VASP/ARHGEF5/ACTR3C/HCLS1/CYFIP1/GPR65/SPAG5/PLEK/RHOC/FHOD1/CARMIL1/HCK/WNT11",17]
[444,"up","up","GO:0051251","positive regulation of lymphocyte activation","23/604","357/18866",1.24274003594766E-3,0.0133579563510195,0.0101098841135164,"IL1B/TNFSF14/MDK/CDKN1A/IL6/CD80/CCL2/LGALS9/MMP14/LILRB1/PNP/TNIP2/SPTA1/HLA-A/HLX/ITPKB/CD40/VNN1/BCL6/JAK3/GLI2/HLA-F/ADA",23]
[445,"up","up","GO:0001783","B cell apoptotic process","5/604","26/18866",1.24498112752283E-3,0.0133579563510195,0.0101098841135164,"AURKB/TRAF3IP2/BLK/BCL6/ADA",5]
[446,"up","up","GO:0002347","response to tumor cell","5/604","26/18866",1.24498112752283E-3,0.0133579563510195,0.0101098841135164,"MR1/MICA/PLK5/HLA-A/NECTIN2",5]
[447,"up","up","GO:0002507","tolerance induction","5/604","26/18866",1.24498112752283E-3,0.0133579563510195,0.0101098841135164,"FOXJ1/LGALS9/HLA-B/TNFAIP3/BLK",5]
[448,"up","up","GO:0042832","defense response to protozoan","5/604","26/18866",1.24498112752283E-3,0.0133579563510195,0.0101098841135164,"BATF/GBP2/SLC11A1/CD40/MYD88",5]
[449,"up","up","GO:0060561","apoptotic process involved in morphogenesis","5/604","26/18866",1.24498112752283E-3,0.0133579563510195,0.0101098841135164,"SPI1/TNFRSF1A/TGFB2/VDR/CCN1",5]
[450,"up","up","GO:0060706","cell differentiation involved in embryonic placenta development","5/604","26/18866",1.24498112752283E-3,0.0133579563510195,0.0101098841135164,"SOCS3/SNAI1/ST14/E2F7/LIF",5]
[451,"up","up","GO:0072202","cell differentiation involved in metanephros development","5/604","26/18866",1.24498112752283E-3,0.0133579563510195,0.0101098841135164,"SMO/YAP1/LIF/WWTR1/WNT9B",5]
[452,"up","up","GO:0046916","cellular transition metal ion homeostasis","11/604","116/18866",0.00124567696939567,0.0133579563510195,0.0101098841135164,"HMOX1/FTL/MYC/HAMP/LTF/ALAS2/SLC11A1/MT2A/ACO1/CP/MT1X",11]
[453,"up","up","GO:0002920","regulation of humoral immune response","12/604","134/18866",1.25792553373809E-3,0.0134298789912522,0.0101643183053031,"IL1B/FOXJ1/C1QB/C5AR1/C1QC/C1R/C1S/C2/LTA/VSIG4/C4B/C1QA",12]
[454,"up","up","GO:0046683","response to organophosphorus","12/604","134/18866",1.25792553373809E-3,0.0134298789912522,0.0101643183053031,"IL1B/FOSL1/FOSB/SDC1/IGFBP5/ZFP36L1/AGXT/RELA/EZR/STC1/MMP19/RYR3",12]
[455,"up","up","GO:0003179","heart valve morphogenesis","7/604","52/18866",1.27543955669548E-3,0.0135571393230329,0.0102606344761859,"SOX9/SNAI1/EMILIN1/TGFB2/NOTCH2/NFATC1/CCN1",7]
[456,"up","up","GO:0071622","regulation of granulocyte chemotaxis","7/604","52/18866",1.27543955669548E-3,0.0135571393230329,0.0102606344761859,"MDK/THBS1/C5AR1/CXCL8/RAC2/MSTN/CSF1",7]
[457,"up","up","GO:0022408","negative regulation of cell-cell adhesion","15/604","191/18866",0.00128153814619142,0.0135921562244853,0.0102871367948338,"FOXJ1/IL1RN/MDK/CD80/LGALS9/LGALS3/LILRB1/VSIG4/ERBB2/HLX/CD300A/FGL1/BCL6/JAK3/CEBPB",15]
[458,"up","up","GO:0072678","T cell migration","8/604","67/18866",1.30332488620725E-3,0.013793047431106,0.0104391800239767,"ICAM1/TNFSF14/CCL2/CXCL10/ITGAL/MYO1G/CCL3/MSN",8]
[459,"up","up","GO:0048015","phosphatidylinositol-mediated signaling","15/604","192/18866",0.00135024090998513,0.0142584263413898,0.0107913990856512,"PIRT/PLCD1/OSM/CSF3/SOX9/CEP55/PLCB3/HCLS1/ZFP36L1/PIK3AP1/EZR/TGFB2/ERBB2/HCST/HGF",15]
[460,"up","up","GO:0043254","regulation of protein-containing complex assembly","27/604","449/18866",1.36372198269477E-3,0.0143694792393946,0.0108754487635956,"HSPA1B/SCIN/ICAM1/KIF14/MMP3/CSF3/ABCA1/VASP/ARHGEF5/ACTR3C/LGALS3/HCLS1/CYFIP1/IRGM/BMF/EIF4EBP1/APOE/PLEK/CAPG/MSN/RHOC/SPTA1/LCP1/HJURP/CARMIL1/HCK/GFAP",27]
[461,"up","up","GO:0033209","tumor necrosis factor-mediated signaling pathway","14/604","173/18866",1.38196003915303E-3,0.0145300657478845,0.0109969876388819,"HSPA1B/TNFSF14/TNFRSF11B/CASP4/H2BC11/LTBR/TNFRSF1A/LTA/RELA/TNFAIP3/TNFRSF12A/SPHK1/CD40/TNFRSF8",14]
[462,"up","up","GO:0033033","negative regulation of myeloid cell apoptotic process","4/604","16/18866",1.39242833832953E-3,0.0145527566890563,0.0110141611330636,"IRF7/ITPKB/GHSR/CLEC5A",4]
[463,"up","up","GO:0060413","atrial septum morphogenesis","4/604","16/18866",1.39242833832953E-3,0.0145527566890563,0.0110141611330636,"SMO/TGFB2/NOTCH2/CCN1",4]
[464,"up","up","GO:2000249","regulation of actin cytoskeleton reorganization","6/604","39/18866",0.00139312545981476,0.0145527566890563,0.0110141611330636,"MDK/CSF3/HCLS1/RHOD/NOTCH2/HCK",6]
[465,"up","up","GO:0050671","positive regulation of lymphocyte proliferation","12/604","136/18866",0.00142963379275825,0.0148459848447232,0.0112360889934871,"IL1B/CDKN1A/IL6/CD80/LGALS9/PNP/SPTA1/HLA-A/CD40/BCL6/JAK3/ADA",12]
[466,"up","up","GO:0061614","pri-miRNA transcription by RNA polymerase II","7/604","53/18866",1.42966643810371E-3,0.0148459848447232,0.0112360889934871,"SPI1/FOSL1/SMAD1/SOX9/RELA/TGFB2/NGFR",7]
[467,"up","up","GO:0007052","mitotic spindle organization","11/604","118/18866",1.43202424868317E-3,0.0148459848447232,0.0112360889934871,"HSPA1B/MYBL2/AURKB/DLGAP5/KIFC1/NDC80/PLK1/BCCIP/BIRC5/MISP/WDR62",11]
[468,"up","up","GO:0002753","cytoplasmic pattern recognition receptor signaling pathway","8/604","68/18866",1.43651060288326E-3,0.0148459848447232,0.0112360889934871,"HSPA1B/IRF7/ALPK1/IFIH1/IRGM/RELA/TNFAIP3/IRAK2",8]
[469,"up","up","GO:0072577","endothelial cell apoptotic process","8/604","68/18866",1.43651060288326E-3,0.0148459848447232,0.0112360889934871,"ICAM1/THBS1/AKR1C3/CCL2/TNFAIP3/TNIP2/SERPINE1/CD40",8]
[470,"up","up","GO:0097305","response to alcohol","17/604","234/18866",0.00148136816301812,0.0152496383627653,0.011541591585514,"NQO1/NPAS4/ICAM1/CD14/SPI1/FOSL1/CDKN1A/AKR1C3/SMO/CSF3/ABCA1/FOSB/HAMP/EIF4EBP1/CCL3/SLC2A4/MSTN",17]
[471,"up","up","GO:0001562","response to protozoan","5/604","27/18866",0.00148815327946936,0.0152496383627653,0.011541591585514,"BATF/GBP2/SLC11A1/CD40/MYD88",5]
[472,"up","up","GO:0002825","regulation of T-helper 1 type immune response","5/604","27/18866",0.00148815327946936,0.0152496383627653,0.011541591585514,"IL1B/CD80/SLC11A1/HLX/JAK3",5]
[473,"up","up","GO:0072207","metanephric epithelium development","5/604","27/18866",0.00148815327946936,0.0152496383627653,0.011541591585514,"SOX9/YAP1/LIF/WWTR1/WNT9B",5]
[474,"up","up","GO:0019730","antimicrobial humoral response","12/604","137/18866",0.00152248170960992,0.0155684996761167,0.0117829197379316,"JCHAIN/CXCL1/CXCL5/H2BC21/CXCL8/CXCL3/H2BC11/CXCL10/LTF/SLC11A1/PPBP/HLA-A",12]
[475,"up","up","GO:0007568","aging","21/604","319/18866",0.00152853831917199,0.0155975268063718,0.0118048887364307,"NQO1/ICAM1/NFKB2/CDKN1A/BCL2A1/NEK6/AURKB/HAMP/IGFBP5/PITX3/CD68/TIMP1/RELA/ADM/ITGB2/TACR3/C1QA/SERPINE1/PML/BCL6/ADA",21]
[476,"up","up","GO:0008360","regulation of cell shape","13/604","156/18866",1.55415666514694E-3,0.0158256246974101,0.0119775231712452,"ICAM1/CCL2/CYFIP1/RAC2/EZR/ITGB2/CCL3/MSN/RHOD/RHOC/SPTA1/LIMD1/HCK",13]
[477,"up","up","GO:0098742","cell-cell adhesion via plasma-membrane adhesion molecules","19/604","277/18866",0.00157511344224388,0.0159451886292515,0.012068014370895,"SELE/IL1RN/ICAM1/CDH16/CDHR3/CLDN19/PALLD/ITGAL/NEXN/ITGB2/PCDHGB6/CLDN23/PCDHGA6/TGFB2/CLDN2/PCDHGB2/PCDHGC3/NECTIN2/MYPN",19]
[478,"up","up","GO:0007219","Notch signaling pathway","15/604","195/18866",1.57517338941954E-3,0.0159451886292515,0.012068014370895,"MDK/DLGAP5/SOX9/MYC/PGAM2/SNAI1/MMP14/YAP1/AGXT/TGFB2/ETV2/NOTCH2/DTX3L/BCL6/TMEM100",15]
[479,"up","up","GO:0043281","regulation of cysteine-type endopeptidase activity involved in apoptotic process","16/604","215/18866",1.57576755795574E-3,0.0159451886292515,0.012068014370895,"SFN/PLAUR/IFI6/TNFSF14/THBS1/CD44/LGALS9/MYC/SOX2/TNFRSF10B/CFLAR/BIRC5/NGFR/PML/HGF/CCN1",16]
[480,"up","up","GO:0022600","digestive system process","10/604","102/18866",1.59228227145377E-3,0.0160037418223628,0.0121123299818519,"NPC1L1/SOX9/HAMP/SERPINA3/CEL/EZR/VDR/TYMP/ACO1/GHSR",10]
[481,"up","up","GO:0046636","negative regulation of alpha-beta T cell activation","6/604","40/18866",1.59529300607309E-3,0.0160037418223628,0.0121123299818519,"LGALS9/LILRB1/HLX/CD300A/BCL6/JAK3",6]
[482,"up","up","GO:0050892","intestinal absorption","6/604","40/18866",1.59529300607309E-3,0.0160037418223628,0.0121123299818519,"NPC1L1/HAMP/CEL/EZR/VDR/ACO1",6]
[483,"up","up","GO:1902895","positive regulation of pri-miRNA transcription by RNA polymerase II","6/604","40/18866",1.59529300607309E-3,0.0160037418223628,0.0121123299818519,"SPI1/FOSL1/SMAD1/RELA/TGFB2/NGFR",6]
[484,"up","up","GO:2000179","positive regulation of neural precursor cell proliferation","7/604","54/18866",1.59806293419096E-3,0.0160037418223628,0.0121123299818519,"MDK/LHX2/SMO/PITX3/NR2E1/SMARCD3/GLI2",7]
[485,"up","up","GO:0055076","transition metal ion homeostasis","12/604","138/18866",1.62024437861726E-3,0.0161924216559956,0.0122551311111908,"HMOX1/FTL/MYC/HAMP/LTF/ALAS2/SLC11A1/MT2A/STEAP4/ACO1/CP/MT1X",12]
[486,"up","up","GO:0110053","regulation of actin filament organization","19/604","278/18866",0.00164165267347989,0.0163561079727578,0.0123790160566082,"SCIN/ICAM1/ASAP3/CSF3/VASP/ARHGEF5/ACTR3C/ARHGAP6/HCLS1/CYFIP1/GPR65/PLEK/CAPG/RHOC/SPTA1/FHOD1/CARMIL1/HCK/WNT11",19]
[487,"up","up","GO:0031334","positive regulation of protein-containing complex assembly","18/604","257/18866",0.00164337210289521,0.0163561079727578,0.0123790160566082,"HSPA1B/SCIN/ICAM1/MMP3/CSF3/ABCA1/VASP/ARHGEF5/ACTR3C/LGALS3/CYFIP1/BMF/PLEK/MSN/RHOC/LCP1/CARMIL1/HCK",18]
[488,"up","up","GO:0007565","female pregnancy","15/604","196/18866",0.00165678746453964,0.0164221857681465,0.0124290266148329,"IL1B/SPP1/FOSL1/HSD11B2/FOSB/LGALS9/PCSK5/IGFBP5/TIMP1/LIF/ADM/VDR/STC1/AMBP/GHSR",15]
[489,"up","up","GO:0048017","inositol lipid-mediated signaling","15/604","196/18866",0.00165678746453964,0.0164221857681465,0.0124290266148329,"PIRT/PLCD1/OSM/CSF3/SOX9/CEP55/PLCB3/HCLS1/ZFP36L1/PIK3AP1/EZR/TGFB2/ERBB2/HCST/HGF",15]
[490,"up","up","GO:0051216","cartilage development","15/604","197/18866",1.74190673153089E-3,0.0172041965386101,0.0130208864815037,"SCIN/CHI3L1/MDK/SMAD1/CD44/SERPINH1/SOX9/CHST11/SNAI1/TIMP1/RELA/STC1/WNT11/GLI2/CCN1",15]
[491,"up","up","GO:0050729","positive regulation of inflammatory response","13/604","158/18866",0.00174278120496339,0.0172041965386101,0.0130208864815037,"IL1B/MDK/IL6/OSM/NUPR1/TNFRSF1A/LTA/CCL3/TLR2/SERPINE1/C2CD4B/MYD88/CEBPB",13]
[492,"up","up","GO:0030218","erythrocyte differentiation","11/604","121/18866",1.75387178455104E-3,0.0172784889018677,0.013077114183056,"HSPA1B/SPI1/ISG15/SLC4A1/HCLS1/ALAS2/ZFP36L1/ETV2/DYRK3/BCL6/JAK3",11]
[493,"up","up","GO:0001916","positive regulation of T cell mediated cytotoxicity","5/604","28/18866",0.00176453973354272,0.0173483247230863,0.0131299689791745,"MR1/HLA-B/HLA-A/NECTIN2/HLA-F",5]
[494,"up","up","GO:0032695","negative regulation of interleukin-12 production","4/604","17/18866",0.00177513038932127,0.0174171194272069,0.0131820358124539,"THBS1/TLR8/LILRB1/JAK3",4]
[495,"up","up","GO:0048771","tissue remodeling","14/604","178/18866",1.8093679285802E-3,0.0177171845451075,0.0134091381841616,"TNFRSF11B/SPP1/MDK/IL6/MMP14/IGFBP5/RAC2/TIMP1/TNFAIP3/LIF/VDR/NOTCH2/MC4R/TCIRG1",14]
[496,"up","up","GO:0033574","response to testosterone","6/604","41/18866",1.81900246765035E-3,0.0177756148401235,0.0134533607804785,"SPP1/ELK1/THBS1/MSN/CFLAR/MSTN",6]
[497,"up","up","GO:0030098","lymphocyte differentiation","23/604","368/18866",0.00184327904296871,0.017947171906264,0.0135832026523905,"IL1B/FOXJ1/SPI1/MDK/BATF/IL6/CD80/MR1/LGALS9/MMP14/ZFP36L1/PNP/ERBB2/NFAM1/NOTCH2/HLX/ITPKB/VNN1/BCL6/TCIRG1/JAK3/GLI2/ADA",23]
[498,"up","up","GO:0032675","regulation of interleukin-6 production","13/604","159/18866",1.84396360827718E-3,0.017947171906264,0.0135832026523905,"IL1B/FOXJ1/IL6/TLR8/LGALS9/IFIH1/HLA-B/TNFAIP3/MAPKAPK2/TLR2/MYD88/GHSR/HGF",13]
[499,"up","up","GO:0042531","positive regulation of tyrosine phosphorylation of STAT protein","8/604","71/18866",1.90186841525732E-3,0.0184736597369784,0.0139816716109519,"IL6/OSM/SOCS3/HCLS1/TNFRSF1A/LIF/CD40/PARP9",8]
[500,"up","up","GO:0007586","digestion","12/604","141/18866",1.94499266428458E-3,0.0188171246382982,0.0142416208320869,"NPC1L1/SOX9/HAMP/SERPINA3/CEL/EZR/PIR/ADM2/VDR/TYMP/ACO1/GHSR",12]
[501,"up","up","GO:0008584","male gonad development","12/604","141/18866",1.94499266428458E-3,0.0188171246382982,0.0142416208320869,"RAB13/ICAM1/AKR1C3/NUPR1/SOX9/SDC1/MMP14/LHCGR/MGST1/TGFB2/KIF18A/TEX19",12]
[502,"up","up","GO:0042326","negative regulation of phosphorylation","28/604","484/18866",1.97784492360793E-3,0.019087907501132,0.0144465611157081,"SFN/IL1B/HSPB1/CDKN1A/GPRC5A/NUPR1/SLC4A1/SOCS3/MYC/GADD45B/GBP1/CDKN2C/PLK1/TNFAIP3/EMILIN1/LIF/EZR/APOE/PARD3/WWTR1/ITPRIP/MSTN/NIBAN1/AMBP/CD300A/BDKRB1/CHORDC1/HGF",28]
[503,"up","up","GO:0070228","regulation of lymphocyte apoptotic process","7/604","56/18866",0.0019808577415039,0.019087907501132,0.0144465611157081,"AURKB/LGALS9/LGALS3/BLK/BCL6/JAK3/ADA",7]
[504,"up","up","GO:0061448","connective tissue development","18/604","262/18866",0.00203152061329744,0.0195372627235172,0.01478665275134,"SCIN/CHI3L1/MDK/SMAD1/CD44/ZNF516/SERPINH1/SOX9/CHST11/SNAI1/TIMP1/RELA/CFLAR/STC1/CSF1/WNT11/GLI2/CCN1",18]
[505,"up","up","GO:0046546","development of primary male sexual characteristics","12/604","142/18866",0.00206440885539552,0.0198142370734695,0.0149962790225188,"RAB13/ICAM1/AKR1C3/NUPR1/SOX9/SDC1/MMP14/LHCGR/MGST1/TGFB2/KIF18A/TEX19",12]
[506,"up","up","GO:0007263","nitric oxide mediated signal transduction","5/604","29/18866",0.00207673748764708,0.0198156651721703,0.014997359869917,"MAFA/THBS1/FPR1/DDAH2/APOE",5]
[507,"up","up","GO:0033032","regulation of myeloid cell apoptotic process","5/604","29/18866",0.00207673748764708,0.0198156651721703,0.014997359869917,"IRF7/ITPKB/HCAR2/GHSR/CLEC5A",5]
[508,"up","up","GO:0033047","regulation of mitotic sister chromatid segregation","8/604","72/18866",0.00208091057822048,0.0198156651721703,0.014997359869917,"UBE2C/NEK6/AURKB/DLGAP5/NDC80/PLK1/BUB1/BUB1B",8]
[509,"up","up","GO:0061035","regulation of cartilage development","8/604","72/18866",0.00208091057822048,0.0198156651721703,0.014997359869917,"SCIN/MDK/SMAD1/SOX9/RELA/WNT11/GLI2/CCN1",8]
[510,"up","up","GO:0046632","alpha-beta T cell differentiation","10/604","106/18866",0.00212580883625623,0.0202035204496744,0.0152909056642992,"BATF/IL6/CD80/LGALS9/PNP/HLX/ITPKB/BCL6/JAK3/ADA",10]
[511,"up","up","GO:0007260","tyrosine phosphorylation of STAT protein","9/604","89/18866",2.17160749701387E-3,0.0205983983131628,0.0155897664581179,"IL6/OSM/SOCS3/HCLS1/TNFRSF1A/LIF/CD40/PARP9/JAK3",9]
[512,"up","up","GO:1902903","regulation of supramolecular fiber organization","23/604","373/18866",2.18920489471267E-3,0.0206896011180541,0.0156587927196244,"HSPA1B/SCIN/ICAM1/ASAP3/CSF3/VASP/MID1/ARHGEF5/ACTR3C/ARHGAP6/HCLS1/CYFIP1/GPR65/EMILIN1/APOE/PLEK/CAPG/RHOC/SPTA1/FHOD1/CARMIL1/HCK/WNT11",23]
[513,"up","up","GO:0072006","nephron development","12/604","143/18866",0.00218975972221204,0.0206896011180541,0.0156587927196244,"FOXJ1/SMO/SOX9/MYC/YAP1/LIF/WWTR1/CFLAR/KLF15/NOTCH2/WNT9B/WNT11",12]
[514,"up","up","GO:0043406","positive regulation of MAP kinase activity","18/604","264/18866",0.00220703102839625,0.0207400093107191,0.0156969438389142,"IL1B/GADD45G/THBS1/C5AR1/FPR1/MLKL/ERN2/NRK/ARHGEF5/GADD45B/MAPKAPK3/MDFIC/ERBB2/MAPKAPK2/IRAK2/GDF15/CD40/HGF",18]
[515,"up","up","GO:0010839","negative regulation of keratinocyte proliferation","4/604","18/18866",0.0022250474193468,0.0207400093107191,0.0156969438389142,"SFN/KDF1/EPPK1/VDR",4]
[516,"up","up","GO:0032740","positive regulation of interleukin-17 production","4/604","18/18866",0.0022250474193468,0.0207400093107191,0.0156969438389142,"IL6/OSM/SPHK1/MYD88",4]
[517,"up","up","GO:0043011","myeloid dendritic cell differentiation","4/604","18/18866",0.0022250474193468,0.0207400093107191,0.0156969438389142,"SPI1/BATF/LTBR/NOTCH2",4]
[518,"up","up","GO:0051895","negative regulation of focal adhesion assembly","4/604","18/18866",0.0022250474193468,0.0207400093107191,0.0156969438389142,"THBS1/FAM107A/ARHGAP6/MMP14",4]
[519,"up","up","GO:0150078","positive regulation of neuroinflammatory response","4/604","18/18866",0.0022250474193468,0.0207400093107191,0.0156969438389142,"IL1B/IL6/NUPR1/CCL3",4]
[520,"up","up","GO:0150118","negative regulation of cell-substrate junction organization","4/604","18/18866",0.0022250474193468,0.0207400093107191,0.0156969438389142,"THBS1/FAM107A/ARHGAP6/MMP14",4]
[521,"up","up","GO:0002709","regulation of T cell mediated immunity","8/604","73/18866",0.00227294491673724,0.0211052950410448,0.0159734080153847,"IL1B/IL6/MR1/LILRB1/HLA-B/HLA-A/NECTIN2/HLA-F",8]
[522,"up","up","GO:0070227","lymphocyte apoptotic process","8/604","73/18866",0.00227294491673724,0.0211052950410448,0.0159734080153847,"AURKB/LGALS9/LGALS3/TRAF3IP2/BLK/BCL6/JAK3/ADA",8]
[523,"up","up","GO:0051983","regulation of chromosome segregation","10/604","107/18866",0.00227946347609054,0.021125352712449,0.0159885885361287,"MKI67/UBE2C/NEK6/AURKB/DLGAP5/NDC80/PLK1/SPAG5/BUB1/BUB1B",10]
[524,"up","up","GO:0002700","regulation of production of molecular mediator of immune response","12/604","144/18866",0.00232126275485129,0.0214716804823744,0.0162507045011184,"IL1B/HMOX1/IL6/BST2/LILRB1/TGFB2/HLA-A/CD40/MZB1/BCL6/JAK3/HLA-F",12]
[525,"up","up","GO:0001953","negative regulation of cell-matrix adhesion","6/604","43/18866",0.00233681637500062,0.0215331037286962,0.0162971922935524,"THBS1/FAM107A/ARHGAP6/MMP14/SERPINE1/BCL6",6]
[526,"up","up","GO:0150077","regulation of neuroinflammatory response","6/604","43/18866",0.00233681637500062,0.0215331037286962,0.0162971922935524,"IL1B/IL6/MMP3/NUPR1/CCL3/SPHK1",6]
[527,"up","up","GO:0001959","regulation of cytokine-mediated signaling pathway","14/604","183/18866",0.00234123079534204,0.0215331037286962,0.0162971922935524,"HSPA1B/IL1RN/IL6/IRF7/CASP4/SOCS3/H2BC11/TNFRSF1A/IRGM/TNFAIP3/SPHK1/IRAK2/CSF1/PARP9",14]
[528,"up","up","GO:0016049","cell growth","28/604","490/18866",0.00235919500264399,0.0216572313973777,0.0163911375283379,"SFN/HSPA1B/H1-5/SPP1/CDKN1A/FAM107A/BST2/KIF14/LHX2/OSGIN1/SOX9/HAMP/CISH/MMP14/CYFIP1/IGFBP5/CDKN2C/APOE/TNFRSF12A/SPHK1/TGFB2/ERBB2/PML/NME6/BDKRB1/BCL6/WNT11/BTG1",28]
[529,"up","up","GO:0060562","epithelial tube morphogenesis","21/604","331/18866",0.00238820855051148,0.0218821301405087,0.0165613507084519,"MDK/LHX2/SMO/SOX9/VASP/MYC/ST14/CXCL10/MMP14/YAP1/ADM/SPINT1/TGFB2/VDR/GRHL3/PML/NOTCH2/CSF1/WNT9B/WNT11/GLI2",21]
[530,"up","up","GO:0045814","negative regulation of gene expression, epigenetic","11/604","126/18866",0.00241978550681897,0.0219915261940418,0.0166441464142195,"H3C13/H1-5/H1-2/H2AC12/H3C7/SPI1/H2AC4/LHX2/H4C15/H1-3/H2AC19",11]
[531,"up","up","GO:0007259","receptor signaling pathway via JAK-STAT","13/604","164/18866",0.00242538523116206,0.0219915261940418,0.0166441464142195,"IL6/OSM/CCL2/SOCS3/HCLS1/TNFRSF1A/NMI/LIF/IL10RA/CD40/CD300A/PARP9/JAK3",13]
[532,"up","up","GO:0046661","male sex differentiation","13/604","164/18866",0.00242538523116206,0.0219915261940418,0.0166441464142195,"RAB13/ICAM1/AKR1C3/NUPR1/SOX9/SDC1/MMP14/LHCGR/MGST1/TGFB2/KIF18A/TEX19/WNT9B",13]
[533,"up","up","GO:0000132","establishment of mitotic spindle orientation","5/604","30/18866",0.00242737085079686,0.0219915261940418,0.0166441464142195,"CENPA/NDC80/PLK1/BCCIP/MISP",5]
[534,"up","up","GO:0003209","cardiac atrium morphogenesis","5/604","30/18866",0.00242737085079686,0.0219915261940418,0.0166441464142195,"MYH6/SMO/TGFB2/NOTCH2/CCN1",5]
[535,"up","up","GO:0051642","centrosome localization","5/604","30/18866",0.00242737085079686,0.0219915261940418,0.0166441464142195,"DLGAP5/EZR/PARD3/MISP/FHOD1",5]
[536,"up","up","GO:0046849","bone remodeling","9/604","91/18866",0.00253147679319134,0.0228919179414149,0.0173256021686406,"TNFRSF11B/SPP1/MDK/IL6/RAC2/TNFAIP3/NOTCH2/MC4R/TCIRG1",9]
[537,"up","up","GO:0032869","cellular response to insulin stimulus","16/604","226/18866",2.61358454465237E-3,0.0235903990464247,0.0178542431404754,"IL1B/RAB13/SOCS3/CYFIP1/ZFP36L1/RELA/EIF4EBP1/SLC2A4/ATP6V0E1/BCAR3/CFLAR/MSTN/MZB1/TCIRG1/GHSR/LPIN3",16]
[538,"up","up","GO:0045684","positive regulation of epidermis development","6/604","44/18866",0.00263387111662281,0.0236852936962351,0.0179260635512752,"SFN/KDF1/PLAAT4/TGFB2/VDR/FST",6]
[539,"up","up","GO:0045687","positive regulation of glial cell differentiation","6/604","44/18866",0.00263387111662281,0.0236852936962351,0.0179260635512752,"MDK/RELA/LIF/SPINT1/HDAC1/TLR2",6]
[540,"up","up","GO:0035019","somatic stem cell population maintenance","8/604","75/18866",0.00269855911274618,0.0241772939361936,0.0182984307966153,"SPI1/SOX9/MYC/SOX2/YAP1/NR2E1/ASCL2/WNT9B",8]
[541,"up","up","GO:0045685","regulation of glial cell differentiation","8/604","75/18866",0.00269855911274618,0.0241772939361936,0.0182984307966153,"MDK/IL6/NR2E1/RELA/LIF/SPINT1/HDAC1/TLR2",8]
[542,"up","up","GO:0031341","regulation of cell killing","9/604","92/18866",0.0027283163942698,0.0243036440636162,0.0183940580851319,"ICAM1/MR1/LGALS9/MICA/LILRB1/HLA-B/HLA-A/NECTIN2/HLA-F",9]
[543,"up","up","GO:0016064","immunoglobulin mediated immune response","16/604","227/18866",0.00273101548447543,0.0243036440636162,0.0183940580851319,"FOXJ1/C1QB/BATF/IRF7/C1QC/TLR8/C1R/C1S/C2/LTA/C4B/C1QA/CD40/BCL6/TCIRG1/NECTIN2",16]
[544,"up","up","GO:0032026","response to magnesium ion","4/604","19/18866",0.00274776087205729,0.0243036440636162,0.0183940580851319,"CD14/TNFRSF11B/THBS1/RYR3",4]
[545,"up","up","GO:0035988","chondrocyte proliferation","4/604","19/18866",0.00274776087205729,0.0243036440636162,0.0183940580851319,"SOX9/LTF/MMP14/STC1",4]
[546,"up","up","GO:0071800","podosome assembly","4/604","19/18866",0.00274776087205729,0.0243036440636162,0.0183940580851319,"ARHGEF5/MSN/LCP1/HCK",4]
[547,"up","up","GO:0072077","renal vesicle morphogenesis","4/604","19/18866",0.00274776087205729,0.0243036440636162,0.0183940580851319,"SMO/SOX9/LIF/WNT9B",4]
[548,"up","up","GO:2000696","regulation of epithelial cell differentiation involved in kidney development","4/604","19/18866",0.00274776087205729,0.0243036440636162,0.0183940580851319,"YAP1/LIF/WWTR1/WNT9B",4]
[549,"up","up","GO:0014072","response to isoquinoline alkaloid","5/604","31/18866",0.00281908193454989,0.0247987116819661,0.0187687468562544,"FOSB/PITX3/RELA/TACR3/ADA",5]
[550,"up","up","GO:0043278","response to morphine","5/604","31/18866",0.00281908193454989,0.0247987116819661,0.0187687468562544,"FOSB/PITX3/RELA/TACR3/ADA",5]
[551,"up","up","GO:0061842","microtubule organizing center localization","5/604","31/18866",0.00281908193454989,0.0247987116819661,0.0187687468562544,"DLGAP5/EZR/PARD3/MISP/FHOD1",5]
[552,"up","up","GO:0072080","nephron tubule development","9/604","93/18866",0.00293707009996239,0.025789816620503,0.0195188583111535,"SMO/SOX9/MYC/YAP1/LIF/WWTR1/NOTCH2/WNT9B/WNT11",9]
[553,"up","up","GO:0030865","cortical cytoskeleton organization","7/604","60/18866",0.00295604496057792,0.0258363614432063,0.019554085463515,"RAB13/RAC2/EZR/PLEK/RHOD/RHOC/FHOD1",7]
[554,"up","up","GO:0051784","negative regulation of nuclear division","7/604","60/18866",0.00295604496057792,0.0258363614432063,0.019554085463515,"AURKB/NDC80/PLK1/LIF/BUB1/BUB1B/NME6",7]
[555,"up","up","GO:0051293","establishment of spindle localization","6/604","45/18866",2.9583619973137E-3,0.0258363614432063,0.019554085463515,"CENPA/NUSAP1/NDC80/PLK1/BCCIP/MISP",6]
[556,"up","up","GO:0098813","nuclear chromosome segregation","18/604","272/18866",0.00304164175979347,0.0265158949815089,0.0200683860902693,"TOP2A/UBE2C/GEM/KIF14/NEK6/AURKB/DLGAP5/KNL1/KIFC1/NUSAP1/NDC80/KIF18B/PLK1/SPAG5/KIF18A/BUB1/BUB1B/NCAPG",18]
[557,"up","up","GO:0014074","response to purine-containing compound","12/604","149/18866",0.00307897976391448,0.0267932045165054,0.0202782660441122,"IL1B/FOSL1/FOSB/SDC1/IGFBP5/ZFP36L1/AGXT/RELA/EZR/STC1/MMP19/RYR3",12]
[558,"up","up","GO:0019724","B cell mediated immunity","16/604","230/18866",0.00310984758086093,0.0270133176065106,0.0204448572331642,"FOXJ1/C1QB/BATF/IRF7/C1QC/TLR8/C1R/C1S/C2/LTA/C4B/C1QA/CD40/BCL6/TCIRG1/NECTIN2",16]
[559,"up","up","GO:0051304","chromosome separation","9/604","94/18866",0.00315823216448773,0.027384528267034,0.0207258056552862,"TOP2A/UBE2C/NEK6/AURKB/DLGAP5/NDC80/PLK1/BUB1/BUB1B",9]
[560,"up","up","GO:0008544","epidermis development","27/604","477/18866",3.18533815146828E-3,0.0274630005615069,0.0207851969111336,"SFN/KDF1/AKR1C3/MCOLN3/LHX2/SMO/EMP1/PALLD/MAFF/PLAAT4/SOX9/MYCL/SNAI1/ST14/IGFBP5/ZFP36L1/YAP1/RELA/HDAC1/TGFB2/VDR/GRHL3/FST/NGFR/PLOD1/FABP5/GLI2",27]
[561,"up","up","GO:0045216","cell-cell junction organization","15/604","210/18866",0.00322336443413848,0.0274630005615069,0.0207851969111336,"IL1B/RAB13/CDHR3/GPBAR1/CLDN19/PARD6G/SNAI1/PARD3/CLDN23/TGFB2/RHOC/CRB3/CLDN2/NECTIN2/WNT11",15]
[562,"up","up","GO:0042267","natural killer cell mediated cytotoxicity","7/604","61/18866",0.00324905109474769,0.0274630005615069,0.0207851969111336,"LGALS9/MICA/LILRB1/HLA-B/HLA-A/NECTIN2/HLA-F",7]
[563,"up","up","GO:0051310","metaphase plate congression","7/604","61/18866",0.00324905109474769,0.0274630005615069,0.0207851969111336,"GEM/KIF14/AURKB/KIFC1/NDC80/SPAG5/KIF18A",7]
[564,"up","up","GO:0019216","regulation of lipid metabolic process","25/604","431/18866",0.00325034141434162,0.0274630005615069,0.0207851969111336,"IL1B/AKR1C3/ABCA1/SOX9/SOCS3/SNAI1/CISH/SERPINA3/TNFRSF1A/TBL1X/SMARCD3/G0S2/ADM/APOE/SPHK1/HELZ2/VDR/PLIN2/PLIN5/ABCB4/FABP5/HCAR2/FPR2/GHSR/CCN1",25]
[565,"up","up","GO:0003176","aortic valve development","5/604","32/18866",0.00325452136080111,0.0274630005615069,0.0207851969111336,"SOX9/SNAI1/TNFRSF1A/EMILIN1/NFATC1",5]
[566,"up","up","GO:0035456","response to interferon-beta","5/604","32/18866",0.00325452136080111,0.0274630005615069,0.0207851969111336,"BST2/IRGM/IFI16/PLSCR1/IFITM3",5]
[567,"up","up","GO:0043304","regulation of mast cell degranulation","5/604","32/18866",0.00325452136080111,0.0274630005615069,0.0207851969111336,"HMOX1/LGALS9/RAC2/BLK/CD300A",5]
[568,"up","up","GO:0050869","negative regulation of B cell activation","5/604","32/18866",0.00325452136080111,0.0274630005615069,0.0207851969111336,"FOXJ1/TNFAIP3/BLK/CD300A/BCL6",5]
[569,"up","up","GO:0061036","positive regulation of cartilage development","5/604","32/18866",0.00325452136080111,0.0274630005615069,0.0207851969111336,"MDK/SMAD1/SOX9/RELA/CCN1",5]
[570,"up","up","GO:0006766","vitamin metabolic process","11/604","131/18866",0.00327693335914235,0.0274630005615069,0.0207851969111336,"IL1B/AKR1C3/TKTL1/SNAI1/ALDH1L1/PLTP/CYP11A1/CYP4F11/VDR/VNN1/BCO1",11]
[571,"up","up","GO:0002676","regulation of chronic inflammatory response","3/604","10/18866",0.00331125483331402,0.0274630005615069,0.0207851969111336,"CYP19A1/LTA/TNFAIP3",3]
[572,"up","up","GO:0002887","negative regulation of myeloid leukocyte mediated immunity","3/604","10/18866",0.00331125483331402,0.0274630005615069,0.0207851969111336,"HMOX1/LGALS9/CD300A",3]
[573,"up","up","GO:0044351","macropinocytosis","3/604","10/18866",0.00331125483331402,0.0274630005615069,0.0207851969111336,"MAPKAPK3/MAPKAPK2/CARMIL1",3]
[574,"up","up","GO:0045625","regulation of T-helper 1 cell differentiation","3/604","10/18866",0.00331125483331402,0.0274630005615069,0.0207851969111336,"CD80/HLX/JAK3",3]
[575,"up","up","GO:0070391","response to lipoteichoic acid","3/604","10/18866",0.00331125483331402,0.0274630005615069,0.0207851969111336,"CD14/RELA/TLR2",3]
[576,"up","up","GO:0071223","cellular response to lipoteichoic acid","3/604","10/18866",0.00331125483331402,0.0274630005615069,0.0207851969111336,"CD14/RELA/TLR2",3]
[577,"up","up","GO:0071394","cellular response to testosterone stimulus","3/604","10/18866",0.00331125483331402,0.0274630005615069,0.0207851969111336,"SPP1/ELK1/MSN",3]
[578,"up","up","GO:0090037","positive regulation of protein kinase C signaling","3/604","10/18866",0.00331125483331402,0.0274630005615069,0.0207851969111336,"MC1R/CD40/WNT11",3]
[579,"up","up","GO:1902946","protein localization to early endosome","3/604","10/18866",0.00331125483331402,0.0274630005615069,0.0207851969111336,"EZR/MSN/DTX3L",3]
[580,"up","up","GO:2000425","regulation of apoptotic cell clearance","3/604","10/18866",0.00331125483331402,0.0274630005615069,0.0207851969111336,"CCL2/C2/C4B",3]
[581,"up","up","GO:0031641","regulation of myelination","6/604","46/18866",0.00331181542612642,0.0274630005615069,0.0207851969111336,"KIF14/TG/PARD3/TYMP/LGI4/HGF",6]
[582,"up","up","GO:0045581","negative regulation of T cell differentiation","6/604","46/18866",0.00331181542612642,0.0274630005615069,0.0207851969111336,"FOXJ1/MDK/ERBB2/HLX/BCL6/JAK3",6]
[583,"up","up","GO:1900744","regulation of p38MAPK cascade","6/604","46/18866",0.00331181542612642,0.0274630005615069,0.0207851969111336,"IL1B/GADD45G/GADD45B/EZR/SPHK1/HGF",6]
[584,"up","up","GO:0032635","interleukin-6 production","13/604","170/18866",3.31332207238037E-3,0.0274630005615069,0.0207851969111336,"IL1B/FOXJ1/IL6/TLR8/LGALS9/IFIH1/HLA-B/TNFAIP3/MAPKAPK2/TLR2/MYD88/GHSR/HGF",13]
[585,"up","up","GO:0002418","immune response to tumor cell","4/604","20/18866",0.00334872221557534,0.0274630005615069,0.0207851969111336,"MR1/MICA/HLA-A/NECTIN2",4]
[586,"up","up","GO:0002827","positive regulation of T-helper 1 type immune response","4/604","20/18866",0.00334872221557534,0.0274630005615069,0.0207851969111336,"IL1B/CD80/SLC11A1/HLX",4]
[587,"up","up","GO:0002902","regulation of B cell apoptotic process","4/604","20/18866",0.00334872221557534,0.0274630005615069,0.0207851969111336,"AURKB/BLK/BCL6/ADA",4]
[588,"up","up","GO:0030903","notochord development","4/604","20/18866",0.00334872221557534,0.0274630005615069,0.0207851969111336,"SOX9/YAP1/WNT11/GLI2",4]
[589,"up","up","GO:0051412","response to corticosterone","4/604","20/18866",0.00334872221557534,0.0274630005615069,0.0207851969111336,"NPAS4/FOSL1/CDKN1A/FOSB",4]
[590,"up","up","GO:0072087","renal vesicle development","4/604","20/18866",0.00334872221557534,0.0274630005615069,0.0207851969111336,"SMO/SOX9/LIF/WNT9B",4]
[591,"up","up","GO:0072234","metanephric nephron tubule development","4/604","20/18866",0.00334872221557534,0.0274630005615069,0.0207851969111336,"SOX9/YAP1/LIF/WWTR1",4]
[592,"up","up","GO:0051896","regulation of protein kinase B signaling","17/604","253/18866",3.35425961056573E-3,0.0274630005615069,0.0207851969111336,"CHI3L1/THBS1/AKR1C3/CD80/OSM/CSF3/HCLS1/IGFBP5/RAC2/PIK3AP1/CCL3/ERBB2/MC1R/MSTN/GDF15/KLB/HGF",17]
[593,"up","up","GO:0050679","positive regulation of epithelial cell proliferation","15/604","211/18866",0.00337079847301013,0.0275518721731536,0.0208524588238933,"MDK/HMOX1/C5AR1/SMO/GPBAR1/LRG1/SOX9/MYC/RREB1/YAP1/TNFAIP3/CFLAR/ERBB2/NOTCH2/GHSR",15]
[594,"up","up","GO:0045930","negative regulation of mitotic cell cycle","21/604","341/18866",0.00338791952882658,0.0276344607059205,0.0209149654284545,"SFN/TOP2A/CDKN1A/FAM107A/AURKB/CCL2/WEE1/NDC80/NABP1/E2F7/ZFP36L1/CDKN2C/PLK1/CDK2/BUB1/BUB1B/PLK5/PML/NME6/BCL6/BTG1",21]
[595,"up","up","GO:0061326","renal tubule development","9/604","95/18866",0.00339230536827371,0.0276344607059205,0.0209149654284545,"SMO/SOX9/MYC/YAP1/LIF/WWTR1/NOTCH2/WNT9B/WNT11",9]
[596,"up","up","GO:0050688","regulation of defense response to virus","8/604","78/18866",0.00345080515512317,0.0280638466222852,0.0212399434221198,"IL1B/TRAF3IP2/LILRB1/TNFAIP3/MICB/HERC5/DTX3L/PARP9",8]
[597,"up","up","GO:0002294","CD4-positive, alpha-beta T cell differentiation involved in immune response","7/604","62/18866",0.0035637047382649,0.0287627887191005,0.021768933292664,"BATF/IL6/CD80/LGALS9/HLX/BCL6/JAK3",7]
[598,"up","up","GO:0030888","regulation of B cell proliferation","7/604","62/18866",0.0035637047382649,0.0287627887191005,0.021768933292664,"CDKN1A/BLK/CD40/CD300A/MZB1/BCL6/ADA",7]
[599,"up","up","GO:0032233","positive regulation of actin filament bundle assembly","7/604","62/18866",0.0035637047382649,0.0287627887191005,0.021768933292664,"ARHGEF5/GPR65/PLEK/RHOC/FHOD1/CARMIL1/WNT11",7]
[600,"up","up","GO:0002429","immune response-activating cell surface receptor signaling pathway","27/604","481/18866",0.00356641964517834,0.0287627887191005,0.021768933292664,"C5AR1/BTN3A1/FPR1/BTN2A3P/BTN3A2/FCGR2A/LGALS3/FCGR3A/MYO1G/CYFIP1/GBP1/RELA/EZR/MICB/PLSCR1/BTN3A3/NFAM1/BLK/HLA-A/CD300A/NECTIN2/FPR2/KLHL6/HCK/LCP2/FYB1/ADA",27]
[601,"up","up","GO:0002757","immune response-activating signal transduction","27/604","481/18866",0.00356641964517834,0.0287627887191005,0.021768933292664,"C5AR1/BTN3A1/FPR1/BTN2A3P/BTN3A2/FCGR2A/LGALS3/FCGR3A/MYO1G/CYFIP1/GBP1/RELA/EZR/MICB/PLSCR1/BTN3A3/NFAM1/BLK/HLA-A/CD300A/NECTIN2/FPR2/KLHL6/HCK/LCP2/FYB1/ADA",27]
[602,"up","up","GO:0030225","macrophage differentiation","6/604","47/18866",3.69577243277731E-3,0.0297071459065864,0.0224836640101753,"SPI1/C1QC/HCLS1/LIF/TLR2/CSF1",6]
[603,"up","up","GO:0046638","positive regulation of alpha-beta T cell differentiation","6/604","47/18866",3.69577243277731E-3,0.0297071459065864,0.0224836640101753,"CD80/LGALS9/PNP/HLX/ITPKB/ADA",6]
[604,"up","up","GO:0050000","chromosome localization","8/604","79/18866",0.00373464362635938,0.0298353150258331,0.0225806679910587,"GEM/KIF14/AURKB/DLGAP5/KIFC1/NDC80/SPAG5/KIF18A",8]
[605,"up","up","GO:0051303","establishment of chromosome localization","8/604","79/18866",0.00373464362635938,0.0298353150258331,0.0225806679910587,"GEM/KIF14/AURKB/DLGAP5/KIFC1/NDC80/SPAG5/KIF18A",8]
[606,"up","up","GO:0003338","metanephros morphogenesis","5/604","33/18866",3.73633922440287E-3,0.0298353150258331,0.0225806679910587,"FOXJ1/SMO/SOX9/LIF/WNT9B",5]
[607,"up","up","GO:0033006","regulation of mast cell activation involved in immune response","5/604","33/18866",3.73633922440287E-3,0.0298353150258331,0.0225806679910587,"HMOX1/LGALS9/RAC2/BLK/CD300A",5]
[608,"up","up","GO:0051051","negative regulation of transport","27/604","483/18866",0.00377098098448722,0.0300624092628447,0.0227525428167209,"IL1B/ICAM1/RRAD/HMOX1/GEM/THBS1/KCNE4/BST2/BAG3/OSM/LGALS9/HAMP/LGALS3/CYFIP1/TNFRSF1A/LILRB1/LIF/APOE/MDFIC/STC1/TLR2/RHBDF2/CD300A/FABP5/GHSR/HLA-F/ADA",27]
[609,"up","up","GO:0000302","response to reactive oxygen species","16/604","235/18866",0.00383720329193771,0.0305401056749131,0.0231140843011026,"NQO1/FOSL1/HMOX1/IL6/AKR1C3/MMP3/SDC1/RELA/TNFAIP3/APOE/SOD3/SPHK1/CFLAR/CDK2/HGF/ADA",16]
[610,"up","up","GO:0030449","regulation of complement activation","10/604","115/18866",0.0038563715035091,0.0306423486516534,0.0231914662462971,"IL1B/C1QB/C5AR1/C1QC/C1R/C1S/C2/VSIG4/C4B/C1QA",10]
[611,"up","up","GO:0002287","alpha-beta T cell activation involved in immune response","7/604","63/18866",0.00390101113491503,0.0306471554813415,0.0231951042647053,"BATF/IL6/CD80/LGALS9/HLX/BCL6/JAK3",7]
[612,"up","up","GO:0002293","alpha-beta T cell differentiation involved in immune response","7/604","63/18866",0.00390101113491503,0.0306471554813415,0.0231951042647053,"BATF/IL6/CD80/LGALS9/HLX/BCL6/JAK3",7]
[613,"up","up","GO:0032613","interleukin-10 production","7/604","63/18866",0.00390101113491503,0.0306471554813415,0.0231951042647053,"ISG15/IL6/LGALS9/LILRB1/TLR2/JAK3/HGF",7]
[614,"up","up","GO:0046635","positive regulation of alpha-beta T cell activation","7/604","63/18866",0.00390101113491503,0.0306471554813415,0.0231951042647053,"CD80/LGALS9/PNP/HLA-A/HLX/ITPKB/ADA",7]
[615,"up","up","GO:0070059","intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress","7/604","63/18866",0.00390101113491503,0.0306471554813415,0.0231951042647053,"CASP4/PPP1R15A/ERN2/ATP2A1/TNFRSF10B/PML/CEBPB",7]
[616,"up","up","GO:1901216","positive regulation of neuron death","9/604","97/18866",0.00390123683350272,0.0306471554813415,0.0231951042647053,"NQO1/MYBL2/ELK1/NUPR1/PITX3/ITGB2/CCL3/TGFB2/C1QA",9]
[617,"up","up","GO:1901655","cellular response to ketone","9/604","97/18866",0.00390123683350272,0.0306471554813415,0.0231951042647053,"NPAS4/ICAM1/SPP1/ELK1/AKR1C3/EIF4EBP1/MSN/CFLAR/MSTN",9]
[618,"up","up","GO:0050769","positive regulation of neurogenesis","27/604","485/18866",0.00398536128917108,0.0312573562598904,0.0236569308342041,"IL1B/MDK/IL6/SMO/CYFIP1/LTA/RELA/SMARCD3/LIF/APOE/TUBB2B/CCL3/SPINT1/HAP1/TNFRSF12A/HDAC1/CFLAR/TLR2/HMG20B/NGFR/PLK5/KCTD11/DPYSL3/CSF1/BCL6/HGF/GLI2",27]
[619,"up","up","GO:0003177","pulmonary valve development","4/604","21/18866",0.00403322638084245,0.0313829254496904,0.0237519670750591,"TNFRSF1A/TGFB2/NOTCH2/NFATC1",4]
[620,"up","up","GO:0051797","regulation of hair follicle development","4/604","21/18866",0.00403322638084245,0.0313829254496904,0.0237519670750591,"SMO/TGFB2/FST/NGFR",4]
[621,"up","up","GO:0060008","Sertoli cell differentiation","4/604","21/18866",0.00403322638084245,0.0313829254496904,0.0237519670750591,"RAB13/ICAM1/SOX9/SDC1",4]
[622,"up","up","GO:1903055","positive regulation of extracellular matrix organization","4/604","21/18866",0.00403322638084245,0.0313829254496904,0.0237519670750591,"IL6/SOX9/EMILIN1/CFLAR",4]
[623,"up","up","GO:1900182","positive regulation of protein localization to nucleus","8/604","80/18866",0.00403619755607908,0.0313829254496904,0.0237519670750591,"BAG3/SMO/HCLS1/PLK1/LIF/NGFR/DTX3L/PARP9",8]
[624,"up","up","GO:0097696","receptor signaling pathway via STAT","13/604","174/18866",0.00404021982269586,0.0313829254496904,0.0237519670750591,"IL6/OSM/CCL2/SOCS3/HCLS1/TNFRSF1A/NMI/LIF/IL10RA/CD40/CD300A/PARP9/JAK3",13]
[625,"up","up","GO:1901617","organic hydroxy compound biosynthetic process","17/604","258/18866",4.08726488323795E-3,0.031697556622487,0.023990093672563,"IL1B/CYP19A1/NPC1L1/HSD3B7/AKR1C3/SPR/SNAI1/PLTP/APOE/PLEK/LHCGR/SPHK1/TGFB2/VDR/MC1R/PMEL/ITPKB",17]
[626,"up","up","GO:0007548","sex differentiation","18/604","280/18866",0.00412392941236678,0.0318885692486827,0.0241346603610826,"RAB13/ICAM1/CYP19A1/AKR1C3/NUPR1/SOX9/SDC1/MMP14/LHCGR/MGST1/TGFB2/KIF18A/FST/MMP19/TEX19/FANCG/WNT9B/CEBPB",18]
[627,"up","up","GO:0003158","endothelium development","11/604","135/18866",0.00412505321207428,0.0318885692486827,0.0241346603610826,"IL1B/ICAM1/CXCL10/TNFRSF1A/ARHGEF26/EZR/MSN/ETV2/STC1/TMEM100/BTG1",11]
[628,"up","up","GO:0050731","positive regulation of peptidyl-tyrosine phosphorylation","14/604","195/18866",0.0041579130446182,0.0320403887555873,0.0242495639871047,"ICAM1/IL6/CD44/CD80/OSM/CSF3/SOCS3/HCLS1/TNFRSF1A/EHD4/LIF/CD40/PARP9/HGF",14]
[629,"up","up","GO:0050864","regulation of B cell activation","14/604","195/18866",0.0041579130446182,0.0320403887555873,0.0242495639871047,"FOXJ1/CDKN1A/IL6/MMP14/ZFP36L1/TNFAIP3/TNIP2/NFAM1/BLK/CD40/CD300A/MZB1/BCL6/ADA",14]
[630,"up","up","GO:0032872","regulation of stress-activated MAPK cascade","16/604","237/18866",0.00416477722270981,0.03204234158488,0.0242510419735066,"IL1B/GADD45G/MYC/MLKL/MID1/ERN2/NRK/ARHGEF5/LTBR/GADD45B/EZR/SPHK1/MDFIC/TGFB2/AMBP/HGF",16]
[631,"up","up","GO:0030316","osteoclast differentiation","9/604","98/18866",0.00417714006124396,0.0320865259538026,0.0242844826314708,"LTF/LILRB1/SBNO2/CCL3/OSCAR/NOTCH2/CSF1/TCIRG1/CEBPB",9]
[632,"up","up","GO:0001885","endothelial cell development","7/604","64/18866",0.00426198658229788,0.0322667765016272,0.0244209041095785,"IL1B/ICAM1/TNFRSF1A/ARHGEF26/EZR/MSN/STC1",7]
[633,"up","up","GO:0042130","negative regulation of T cell proliferation","7/604","64/18866",0.00426198658229788,0.0322667765016272,0.0244209041095785,"FOXJ1/CD80/LGALS9/LILRB1/VSIG4/ERBB2/CEBPB",7]
[634,"up","up","GO:0045453","bone resorption","7/604","64/18866",0.00426198658229788,0.0322667765016272,0.0244209041095785,"TNFRSF11B/SPP1/IL6/RAC2/TNFAIP3/MC4R/TCIRG1",7]
[635,"up","up","GO:2000401","regulation of lymphocyte migration","7/604","64/18866",0.00426198658229788,0.0322667765016272,0.0244209041095785,"TNFSF14/CCL4/CCL2/CXCL10/CCL3/MSN/SLC8B1",7]
[636,"up","up","GO:0007094","mitotic spindle assembly checkpoint","5/604","34/18866",0.00426717634362348,0.0322667765016272,0.0244209041095785,"AURKB/NDC80/PLK1/BUB1/BUB1B",5]
[637,"up","up","GO:0031577","spindle checkpoint","5/604","34/18866",0.00426717634362348,0.0322667765016272,0.0244209041095785,"AURKB/NDC80/PLK1/BUB1/BUB1B",5]
[638,"up","up","GO:0043516","regulation of DNA damage response, signal transduction by p53 class mediator","5/604","34/18866",0.00426717634362348,0.0322667765016272,0.0244209041095785,"CD44/SNAI1/HIC1/PTTG1IP/DYRK3",5]
[639,"up","up","GO:0055094","response to lipoprotein particle","5/604","34/18866",0.00426717634362348,0.0322667765016272,0.0244209041095785,"ABCA1/CD68/APOE/ITGB2/MYD88",5]
[640,"up","up","GO:0071173","spindle assembly checkpoint","5/604","34/18866",0.00426717634362348,0.0322667765016272,0.0244209041095785,"AURKB/NDC80/PLK1/BUB1/BUB1B",5]
[641,"up","up","GO:0071174","mitotic spindle checkpoint","5/604","34/18866",0.00426717634362348,0.0322667765016272,0.0244209041095785,"AURKB/NDC80/PLK1/BUB1/BUB1B",5]
[642,"up","up","GO:0050829","defense response to Gram-negative bacterium","8/604","81/18866",0.00435618320447662,0.0328752690302692,0.0248814378010246,"IL6/MR1/H2BC11/GSDMD/LTF/IRGM/SLC11A1/SERPINE1",8]
[643,"up","up","GO:0045446","endothelial cell differentiation","10/604","117/18866",4.36121270609925E-3,0.0328752690302692,0.0248814378010246,"IL1B/ICAM1/TNFRSF1A/ARHGEF26/EZR/MSN/ETV2/STC1/TMEM100/BTG1",10]
[644,"up","up","GO:0010810","regulation of cell-substrate adhesion","15/604","217/18866",0.00437609697509391,0.0329362454010562,0.0249275873785588,"MDK/THBS1/FAM107A/RREB1/ARHGAP6/MMP14/GBP1/RAC2/EMILIN1/RHOD/SERPINE1/CSF1/CARMIL1/BCL6/CCN1",15]
[645,"up","up","GO:0002604","regulation of dendritic cell antigen processing and presentation","3/604","11/18866",0.00444540927140222,0.0330473907032002,0.025011706991987,"THBS1/CD68/SLC11A1",3]
[646,"up","up","GO:0007614","short-term memory","3/604","11/18866",0.00444540927140222,0.0330473907032002,0.025011706991987,"NPAS4/MDK/SLC2A4",3]
[647,"up","up","GO:0035747","natural killer cell chemotaxis","3/604","11/18866",0.00444540927140222,0.0330473907032002,0.025011706991987,"CCL4/CCL2/CCL3",3]
[648,"up","up","GO:0071803","positive regulation of podosome assembly","3/604","11/18866",0.00444540927140222,0.0330473907032002,0.025011706991987,"ARHGEF5/MSN/LCP1",3]
[649,"up","up","GO:0072697","protein localization to cell cortex","3/604","11/18866",0.00444540927140222,0.0330473907032002,0.025011706991987,"PLK1/EZR/MISP",3]
[650,"up","up","GO:0097048","dendritic cell apoptotic process","3/604","11/18866",0.00444540927140222,0.0330473907032002,0.025011706991987,"LGALS9/LILRB1/BLK",3]
[651,"up","up","GO:0098883","synapse pruning","3/604","11/18866",0.00444540927140222,0.0330473907032002,0.025011706991987,"C1QB/C1QC/C1QA",3]
[652,"up","up","GO:2000668","regulation of dendritic cell apoptotic process","3/604","11/18866",0.00444540927140222,0.0330473907032002,0.025011706991987,"LGALS9/LILRB1/BLK",3]
[653,"up","up","GO:0000187","activation of MAPK activity","12/604","156/18866",0.00446422097550151,0.0331364151121835,0.0250790845484368,"IL1B/THBS1/C5AR1/FPR1/MLKL/ERN2/MAPKAPK3/MDFIC/MAPKAPK2/IRAK2/GDF15/HGF",12]
[654,"up","up","GO:0002686","negative regulation of leukocyte migration","6/604","49/18866",0.00456141457804548,0.0337544678775365,0.0255468538440956,"CYP19A1/HMOX1/CCL2/EMILIN1/CD300A/ADA",6]
[655,"up","up","GO:0032663","regulation of interleukin-2 production","6/604","49/18866",0.00456141457804548,0.0337544678775365,0.0255468538440956,"IL1B/CD80/GBP1/TNFAIP3/EZR/VSIG4",6]
[656,"up","up","GO:0001894","tissue homeostasis","17/604","261/18866",0.00458704514936843,0.0338923899984585,0.0256512393221261,"JCHAIN/HSPB1/TNFRSF11B/SPP1/IL6/SMO/SOX9/LTF/SERPINA3/USH1G/YAP1/RAC2/TNFAIP3/WWTR1/CSF1/MC4R/TCIRG1",17]
[657,"up","up","GO:0032729","positive regulation of interferon-gamma production","7/604","65/18866",0.00464765695600603,0.0341839048038865,0.0258718704443431,"IL1B/CD14/TLR8/LGALS9/LTA/SLC11A1/HLA-A",7]
[658,"up","up","GO:0045604","regulation of epidermal cell differentiation","7/604","65/18866",0.00464765695600603,0.0341839048038865,0.0258718704443431,"SFN/KDF1/MAFF/PLAAT4/MYCL/ZFP36L1/VDR",7]
[659,"up","up","GO:0046782","regulation of viral transcription","7/604","65/18866",0.00464765695600603,0.0341839048038865,0.0258718704443431,"CCL4/CCL3/HDAC1/MDFIC/IFITM3/TRIM21/TRIM14",7]
[660,"up","up","GO:0042113","B cell activation","20/604","328/18866",0.00466671285268942,0.0342720563590691,0.0259385873869579,"FOXJ1/CD180/CDKN1A/BATF/IL6/BST2/MMP14/ZFP36L1/TNFAIP3/TNIP2/NFAM1/BLK/NOTCH2/CD40/CD300A/MZB1/BCL6/TCIRG1/JAK3/ADA",20]
[661,"up","up","GO:0070302","regulation of stress-activated protein kinase signaling cascade","16/604","240/18866",4.69879958625803E-3,0.0344554940916682,0.0260774210655454,"IL1B/GADD45G/MYC/MLKL/MID1/ERN2/NRK/ARHGEF5/LTBR/GADD45B/EZR/SPHK1/MDFIC/TGFB2/AMBP/HGF",16]
[662,"up","up","GO:0001933","negative regulation of protein phosphorylation","25/604","444/18866",0.00474805729943074,0.034764099290545,0.0263109869431009,"SFN/IL1B/HSPB1/CDKN1A/GPRC5A/SOCS3/MYC/GADD45B/GBP1/CDKN2C/PLK1/TNFAIP3/EMILIN1/LIF/EZR/APOE/PARD3/WWTR1/ITPRIP/NIBAN1/AMBP/CD300A/BDKRB1/CHORDC1/HGF",25]
[663,"up","up","GO:0008585","female gonad development","9/604","100/18866",0.00477448725385058,0.0348750979498066,0.0263949955707982,"ICAM1/CYP19A1/NUPR1/MMP14/LHCGR/FST/MMP19/FANCG/CEBPB",9]
[664,"up","up","GO:0042359","vitamin D metabolic process","4/604","22/18866",0.00480638857653617,0.0348750979498066,0.0263949955707982,"IL1B/SNAI1/CYP11A1/VDR",4]
[665,"up","up","GO:0045655","regulation of monocyte differentiation","4/604","22/18866",0.00480638857653617,0.0348750979498066,0.0263949955707982,"IRF7/MYC/ZFP36L1/CSF1",4]
[666,"up","up","GO:0060972","left/right pattern formation","4/604","22/18866",0.00480638857653617,0.0348750979498066,0.0263949955707982,"FOXJ1/SMO/SNAI1/NOTCH2",4]
[667,"up","up","GO:0071459","protein localization to chromosome, centromeric region","4/604","22/18866",0.00480638857653617,0.0348750979498066,0.0263949955707982,"CENPA/AURKB/KNL1/NDC80",4]
[668,"up","up","GO:1901739","regulation of myoblast fusion","4/604","22/18866",0.00480638857653617,0.0348750979498066,0.0263949955707982,"TNFSF14/CXCL10/CFLAR/GDF15",4]
[669,"up","up","GO:0050730","regulation of peptidyl-tyrosine phosphorylation","17/604","263/18866",0.00494726368815266,0.0358436279468998,0.0271280213251704,"ICAM1/IL6/GPRC5A/CD44/CD80/OSM/CSF3/SOCS3/HCLS1/TNFRSF1A/EHD4/LIF/ITGB2/CD40/CD300A/PARP9/HGF",17]
[670,"up","up","GO:0001961","positive regulation of cytokine-mediated signaling pathway","6/604","50/18866",0.00504622514297284,0.0362204511899328,0.0274132175945872,"HSPA1B/IRF7/CASP4/IRGM/CSF1/PARP9",6]
[671,"up","up","GO:0010718","positive regulation of epithelial to mesenchymal transition","6/604","50/18866",0.00504622514297284,0.0362204511899328,0.0274132175945872,"IL1B/MDK/IL6/SNAI1/WWTR1/TGFB2",6]
[672,"up","up","GO:0014009","glial cell proliferation","6/604","50/18866",0.00504622514297284,0.0362204511899328,0.0274132175945872,"IL1B/IL6/LTA/CSF1/LGI4/ASCL2",6]
[673,"up","up","GO:0046850","regulation of bone remodeling","6/604","50/18866",0.00504622514297284,0.0362204511899328,0.0274132175945872,"TNFRSF11B/SPP1/MDK/IL6/TNFAIP3/MC4R",6]
[674,"up","up","GO:0050873","brown fat cell differentiation","6/604","50/18866",0.00504622514297284,0.0362204511899328,0.0274132175945872,"ZNF516/LRG1/PIM1/RREB1/SLC2A4/CEBPB",6]
[675,"up","up","GO:0051653","spindle localization","6/604","50/18866",0.00504622514297284,0.0362204511899328,0.0274132175945872,"CENPA/NUSAP1/NDC80/PLK1/BCCIP/MISP",6]
[676,"up","up","GO:0048145","regulation of fibroblast proliferation","8/604","83/18866",0.00505435519907515,0.0362204511899328,0.0274132175945872,"CDKN1A/NUPR1/MYC/LTA/SPHK1/NGFR/PML/CD300A",8]
[677,"up","up","GO:0002228","natural killer cell mediated immunity","7/604","66/18866",0.00505905621117898,0.0362204511899328,0.0274132175945872,"LGALS9/MICA/LILRB1/HLA-B/HLA-A/NECTIN2/HLA-F",7]
[678,"up","up","GO:0045639","positive regulation of myeloid cell differentiation","9/604","101/18866",0.00509701712626262,0.0364384100457152,0.0275781783651998,"HSPA1B/SCIN/ISG15/CSF3/HCLS1/ZFP36L1/LIF/NOTCH2/CSF1",9]
[679,"up","up","GO:0008154","actin polymerization or depolymerization","15/604","221/18866",0.00517284861378529,0.0369260636686558,0.0279472559011576,"SCIN/ICAM1/FAM107A/CSF3/VASP/ACTR3C/ARHGAP6/HCLS1/CYFIP1/PLEK/CAPG/SPTA1/CARMIL1/GHSR/HCK",15]
[680,"up","up","GO:0030522","intracellular receptor signaling pathway","17/604","265/18866",0.00533029404137441,0.0379940223802085,0.0287555336442567,"HSPA1B/AKR1C3/IRF7/ALPK1/PIM1/YAP1/IFIH1/IRGM/RELA/TNFAIP3/HDAC1/VDR/IRAK2/PML/PLIN5/CTBP2/FABP5",17]
[681,"up","up","GO:0033045","regulation of sister chromatid segregation","8/604","84/18866",0.00543401226436665,0.0386197323246117,0.0292290982270686,"UBE2C/NEK6/AURKB/DLGAP5/NDC80/PLK1/BUB1/BUB1B",8]
[682,"up","up","GO:0048144","fibroblast proliferation","8/604","84/18866",0.00543401226436665,0.0386197323246117,0.0292290982270686,"CDKN1A/NUPR1/MYC/LTA/SPHK1/NGFR/PML/CD300A",8]
[683,"up","up","GO:0001893","maternal placenta development","5/604","36/18866",0.00548637497622106,0.0387080924450415,0.0292959730209613,"SPP1/LIF/VDR/STC1/GHSR",5]
[684,"up","up","GO:0045841","negative regulation of mitotic metaphase/anaphase transition","5/604","36/18866",0.00548637497622106,0.0387080924450415,0.0292959730209613,"AURKB/NDC80/PLK1/BUB1/BUB1B",5]
[685,"up","up","GO:0051294","establishment of spindle orientation","5/604","36/18866",0.00548637497622106,0.0387080924450415,0.0292959730209613,"CENPA/NDC80/PLK1/BCCIP/MISP",5]
[686,"up","up","GO:0071402","cellular response to lipoprotein particle stimulus","5/604","36/18866",0.00548637497622106,0.0387080924450415,0.0292959730209613,"ABCA1/CD68/APOE/ITGB2/MYD88",5]
[687,"up","up","GO:1905332","positive regulation of morphogenesis of an epithelium","5/604","36/18866",0.00548637497622106,0.0387080924450415,0.0292959730209613,"MDK/SMO/SOX9/RREB1/LIF",5]
[688,"up","up","GO:0072593","reactive oxygen species metabolic process","18/604","288/18866",0.00550607846082996,0.0387906428773879,0.0293584507894621,"NQO1/IL1B/IFI6/ICAM1/CDKN1A/THBS1/AKR1C3/MMP3/DDAH2/SPR/RAC2/ITGB2/SOD3/CFLAR/TLR2/PLIN5/FPR2/CCN1",18]
[689,"up","up","GO:0030323","respiratory tube development","13/604","181/18866",0.00561883968748958,0.0395275993690305,0.0299162116124073,"FOXJ1/CHI3L1/SOX9/MMP14/PCSK5/IGFBP5/YAP1/LIF/EIF4EBP1/ADAMTS2/WNT11/GLI2/ADA",13]
[690,"up","up","GO:0006907","pinocytosis","4/604","23/18866",0.00567312422368114,0.0396791242600036,0.0300308922602397,"EHD4/MAPKAPK3/MAPKAPK2/CARMIL1",4]
[691,"up","up","GO:0032703","negative regulation of interleukin-2 production","4/604","23/18866",0.00567312422368114,0.0396791242600036,0.0300308922602397,"GBP1/TNFAIP3/EZR/VSIG4",4]
[692,"up","up","GO:0045649","regulation of macrophage differentiation","4/604","23/18866",0.00567312422368114,0.0396791242600036,0.0300308922602397,"C1QC/HCLS1/LIF/CSF1",4]
[693,"up","up","GO:0072243","metanephric nephron epithelium development","4/604","23/18866",0.00567312422368114,0.0396791242600036,0.0300308922602397,"SOX9/YAP1/LIF/WWTR1",4]
[694,"up","up","GO:0002468","dendritic cell antigen processing and presentation","3/604","12/18866",0.00578741349215993,0.0399026930248922,0.0302000988547988,"THBS1/CD68/SLC11A1",3]
[695,"up","up","GO:0003334","keratinocyte development","3/604","12/18866",0.00578741349215993,0.0399026930248922,0.0302000988547988,"SFN/KDF1/PALLD",3]
[696,"up","up","GO:0007077","mitotic nuclear envelope disassembly","3/604","12/18866",0.00578741349215993,0.0399026930248922,0.0302000988547988,"NEK6/PLK1/CCNB2",3]
[697,"up","up","GO:0032494","response to peptidoglycan","3/604","12/18866",0.00578741349215993,0.0399026930248922,0.0302000988547988,"IL6/C5AR1/RELA",3]
[698,"up","up","GO:0033004","negative regulation of mast cell activation","3/604","12/18866",0.00578741349215993,0.0399026930248922,0.0302000988547988,"HMOX1/LGALS9/CD300A",3]
[699,"up","up","GO:0042368","vitamin D biosynthetic process","3/604","12/18866",0.00578741349215993,0.0399026930248922,0.0302000988547988,"IL1B/SNAI1/VDR",3]
[700,"up","up","GO:0051639","actin filament network formation","3/604","12/18866",0.00578741349215993,0.0399026930248922,0.0302000988547988,"FHOD1/LCP1/CARMIL1",3]
[701,"up","up","GO:1902337","regulation of apoptotic process involved in morphogenesis","3/604","12/18866",0.00578741349215993,0.0399026930248922,0.0302000988547988,"TNFRSF1A/TGFB2/VDR",3]
[702,"up","up","GO:1905668","positive regulation of protein localization to endosome","3/604","12/18866",0.00578741349215993,0.0399026930248922,0.0302000988547988,"EZR/MSN/DTX3L",3]
[703,"up","up","GO:2001204","regulation of osteoclast development","3/604","12/18866",0.00578741349215993,0.0399026930248922,0.0302000988547988,"LTF/LILRB1/NOTCH2",3]
[704,"up","up","GO:0019935","cyclic-nucleotide-mediated signaling","15/604","224/18866",0.00584438851695014,0.0402382828716723,0.0304540878911053,"THBS1/ABCA1/GPR101/SOX9/CXCL10/GPR65/ADM/APOE/LHCGR/ADM2/ADGRE1/MC1R/IRAG1/RAMP1/MC4R",15]
[705,"up","up","GO:0010812","negative regulation of cell-substrate adhesion","7/604","68/18866",5.96320846969557E-3,0.0409981155356233,0.0310291623992371,"THBS1/FAM107A/ARHGAP6/MMP14/GBP1/SERPINE1/BCL6",7]
[706,"up","up","GO:0046425","regulation of receptor signaling pathway via JAK-STAT","11/604","142/18866",0.00602236775973391,0.0413461990530174,0.0312926071905064,"IL6/OSM/SOCS3/HCLS1/TNFRSF1A/LIF/IL10RA/CD40/CD300A/PARP9/JAK3",11]
[707,"up","up","GO:0006909","phagocytosis","22/604","382/18866",0.00603475173895052,0.0413726190646297,0.03131260300788,"IL1B/CD14/THBS1/MSR1/CCL2/ABCA1/FCGR2A/ITGAL/FCGR3A/MYO1G/C2/CYFIP1/RAC2/ITGB2/SLC11A1/SPHK1/C4B/TLR2/CD300A/MYD88/FPR2/HCK",22]
[708,"up","up","GO:0045839","negative regulation of mitotic nuclear division","6/604","52/18866",0.0061276545179235,0.0417186120508709,0.0315744655939724,"AURKB/NDC80/PLK1/BUB1/BUB1B/NME6",6]
[709,"up","up","GO:0051496","positive regulation of stress fiber assembly","6/604","52/18866",0.0061276545179235,0.0417186120508709,0.0315744655939724,"ARHGEF5/GPR65/RHOC/FHOD1/CARMIL1/WNT11",6]
[710,"up","up","GO:0072132","mesenchyme morphogenesis","6/604","52/18866",0.0061276545179235,0.0417186120508709,0.0315744655939724,"SOX9/MYC/SNAI1/TGFB2/TMEM100/WNT11",6]
[711,"up","up","GO:0006986","response to unfolded protein","13/604","183/18866",6.1504554631894E-3,0.0417186120508709,0.0315744655939724,"HSPA1B/HSPB1/THBS1/BAG3/CCL2/CXCL8/SERPINH1/PPP1R15A/ERN2/FKBP14/HSPA7/TOR1B/DNAJB1",13]
[712,"up","up","GO:1903034","regulation of response to wounding","13/604","183/18866",6.1504554631894E-3,0.0417186120508709,0.0315744655939724,"PLAUR/SPP1/MDK/THBS1/CLDN19/RREB1/TNFAIP3/APOE/PLEK/TNFRSF12A/EPPK1/SERPINE1/BLK",13]
[713,"up","up","GO:0032231","regulation of actin filament bundle assembly","9/604","104/18866",0.0061666682074067,0.0417186120508709,0.0315744655939724,"ASAP3/ARHGEF5/ARHGAP6/GPR65/PLEK/RHOC/FHOD1/CARMIL1/WNT11",9]
[714,"up","up","GO:0032649","regulation of interferon-gamma production","9/604","104/18866",0.0061666682074067,0.0417186120508709,0.0315744655939724,"IL1B/CD14/ISG15/TLR8/LGALS9/LTA/LILRB1/SLC11A1/HLA-A",9]
[715,"up","up","GO:0030212","hyaluronan metabolic process","5/604","37/18866",0.00617989755570978,0.0417186120508709,0.0315744655939724,"IL1B/CD44/PIM1/ITIH1/HGF",5]
[716,"up","up","GO:0070423","nucleotide-binding oligomerization domain containing signaling pathway","5/604","37/18866",0.00617989755570978,0.0417186120508709,0.0315744655939724,"HSPA1B/IRGM/RELA/TNFAIP3/IRAK2",5]
[717,"up","up","GO:0097242","amyloid-beta clearance","5/604","37/18866",0.00617989755570978,0.0417186120508709,0.0315744655939724,"C5AR1/MSR1/APOE/ITGB2/HDAC1",5]
[718,"up","up","GO:1902100","negative regulation of metaphase/anaphase transition of cell cycle","5/604","37/18866",0.00617989755570978,0.0417186120508709,0.0315744655939724,"AURKB/NDC80/PLK1/BUB1/BUB1B",5]
[719,"up","up","GO:0042509","regulation of tyrosine phosphorylation of STAT protein","8/604","86/18866",0.0062581908811943,0.0421883883187048,0.0319300127676775,"IL6/OSM/SOCS3/HCLS1/TNFRSF1A/LIF/CD40/PARP9",8]
[720,"up","up","GO:0046545","development of primary female sexual characteristics","9/604","105/18866",0.00655911185194176,0.044155576592169,0.0334188666725395,"ICAM1/CYP19A1/NUPR1/MMP14/LHCGR/FST/MMP19/FANCG/CEBPB",9]
[721,"up","up","GO:0033622","integrin activation","4/604","24/18866",0.0066381317687905,0.0445021088289454,0.0336811373869621,"KIF14/FERMT3/PLEK/MZB1",4]
[722,"up","up","GO:0098581","detection of external biotic stimulus","4/604","24/18866",0.0066381317687905,0.0445021088289454,0.0336811373869621,"HLA-B/C4B/TLR2/HLA-A",4]
[723,"up","up","GO:1903306","negative regulation of regulated secretory pathway","4/604","24/18866",0.0066381317687905,0.0445021088289454,0.0336811373869621,"HMOX1/LGALS9/CD300A/HLA-F",4]
[724,"up","up","GO:0050852","T cell receptor signaling pathway","14/604","206/18866",0.00670011944895943,0.0448556339352297,0.0339487006100954,"BTN3A1/BTN2A3P/BTN3A2/LGALS3/GBP1/RELA/EZR/BTN3A3/HLA-A/CD300A/NECTIN2/LCP2/FYB1/ADA",14]
[725,"up","up","GO:0045661","regulation of myoblast differentiation","6/604","53/18866",0.00672739767704942,0.0449141825628906,0.0339930127657202,"TNFSF14/SOX9/CXCL10/ZFP36L1/MSTN/BTG1",6]
[726,"up","up","GO:0061756","leukocyte adhesion to vascular endothelial cell","6/604","53/18866",0.00672739767704942,0.0449141825628906,0.0339930127657202,"SELE/ICAM1/MDK/IL6/RELA/ITGB2",6]
[727,"up","up","GO:0035872","nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway","5/604","38/18866",6.9327464253466E-3,0.0461579971478777,0.0349343859056288,"HSPA1B/IRGM/RELA/TNFAIP3/IRAK2",5]
[728,"up","up","GO:0043029","T cell homeostasis","5/604","38/18866",6.9327464253466E-3,0.0461579971478777,0.0349343859056288,"TNFSF14/LGALS9/CCNB2/TCIRG1/JAK3",5]
[729,"up","up","GO:0002708","positive regulation of lymphocyte mediated immunity","9/604","106/18866",0.00697044924514967,0.0463005771904705,0.0350422967019838,"IL1B/IL6/MR1/LTA/HLA-B/HLA-A/CD40/NECTIN2/HLA-F",9]
[730,"up","up","GO:0032370","positive regulation of lipid transport","7/604","70/18866",0.00698281863549287,0.0463005771904705,0.0350422967019838,"IL1B/CYP19A1/SPP1/ABCA1/PLTP/APOE/ABCB4",7]
[731,"up","up","GO:0050795","regulation of behavior","7/604","70/18866",0.00698281863549287,0.0463005771904705,0.0350422967019838,"MDK/APOE/CCL3/TACR3/MC4R/GHSR/ADA",7]
[732,"up","up","GO:1901991","negative regulation of mitotic cell cycle phase transition","16/604","251/18866",0.0071547842715134,0.0473760100601441,0.0358562312140124,"SFN/CDKN1A/FAM107A/AURKB/CCL2/WEE1/NDC80/E2F7/ZFP36L1/CDKN2C/PLK1/CDK2/BUB1/BUB1B/PLK5/PML",16]
[733,"up","up","GO:0014068","positive regulation of phosphatidylinositol 3-kinase signaling","8/604","88/18866",0.00717387433243799,0.0474376110359167,0.0359028535198484,"OSM/CSF3/SOX9/HCLS1/PIK3AP1/TGFB2/HCST/HGF",8]
[734,"up","up","GO:1903531","negative regulation of secretion by cell","12/604","166/18866",0.00726385333157116,0.0478607662372009,0.0362231158365229,"IL1B/HMOX1/OSM/LGALS9/TNFRSF1A/LILRB1/LIF/APOE/RHBDF2/CD300A/GHSR/HLA-F",12]
[735,"up","up","GO:2000134","negative regulation of G1/S transition of mitotic cell cycle","10/604","126/18866",0.00730974072297296,0.0478607662372009,0.0362231158365229,"SFN/CDKN1A/FAM107A/CCL2/WEE1/E2F7/CDKN2C/CDK2/PLK5/PML",10]
[736,"up","up","GO:0043405","regulation of MAP kinase activity","20/604","342/18866",0.00731775809602524,0.0478607662372009,0.0362231158365229,"IL1B/GADD45G/THBS1/C5AR1/FPR1/MLKL/ERN2/NRK/ARHGEF5/GADD45B/MAPKAPK3/APOE/MDFIC/ERBB2/MAPKAPK2/IRAK2/GDF15/CD40/CD300A/HGF",20]
[737,"up","up","GO:0002430","complement receptor mediated signaling pathway","3/604","13/18866",0.00734648443995822,0.0478607662372009,0.0362231158365229,"C5AR1/FPR1/FPR2",3]
[738,"up","up","GO:0002903","negative regulation of B cell apoptotic process","3/604","13/18866",0.00734648443995822,0.0478607662372009,0.0362231158365229,"AURKB/BCL6/ADA",3]
[739,"up","up","GO:0003337","mesenchymal to epithelial transition involved in metanephros morphogenesis","3/604","13/18866",0.00734648443995822,0.0478607662372009,0.0362231158365229,"SMO/LIF/WNT9B",3]
[740,"up","up","GO:0035563","positive regulation of chromatin binding","3/604","13/18866",0.00734648443995822,0.0478607662372009,0.0362231158365229,"CTBP2/DTX3L/PARP9",3]
[741,"up","up","GO:0046348","amino sugar catabolic process","3/604","13/18866",0.00734648443995822,0.0478607662372009,0.0362231158365229,"CHI3L2/CHI3L1/NPL",3]
[742,"up","up","GO:0072182","regulation of nephron tubule epithelial cell differentiation","3/604","13/18866",0.00734648443995822,0.0478607662372009,0.0362231158365229,"YAP1/LIF/WWTR1",3]
[743,"up","up","GO:0072683","T cell extravasation","3/604","13/18866",0.00734648443995822,0.0478607662372009,0.0362231158365229,"ICAM1/CCL2/ITGAL",3]
[744,"up","up","GO:1905666","regulation of protein localization to endosome","3/604","13/18866",0.00734648443995822,0.0478607662372009,0.0362231158365229,"EZR/MSN/DTX3L",3]
[745,"up","up","GO:0006968","cellular defense response","6/604","54/18866",0.00736856451990674,0.0479401774872322,0.0362832177348993,"FOSL1/LSP1/C5AR1/RELA/TCIRG1/CLEC5A",6]
[746,"up","up","GO:0007160","cell-matrix adhesion","15/604","230/18866",0.00739815928665458,0.0480682011560519,0.0363801116325543,"THBS1/SIGLEC1/FAM107A/CD44/FERMT3/PARVG/ARHGAP6/ITGAL/MMP14/EMILIN1/ITGB2/RHOD/SERPINE1/CSF1/BCL6",15]
[747,"up","up","GO:0002292","T cell differentiation involved in immune response","7/604","71/18866",0.00753854756583115,0.048784165622942,0.0369219847753799,"BATF/IL6/CD80/LGALS9/HLX/BCL6/JAK3",7]
[748,"up","up","GO:0033627","cell adhesion mediated by integrin","7/604","71/18866",0.00753854756583115,0.048784165622942,0.0369219847753799,"ICAM1/FERMT3/LIF/ITGB2/TGFB2/SERPINE1/ADA",7]
[749,"up","up","GO:0061180","mammary gland epithelium development","7/604","71/18866",0.00753854756583115,0.048784165622942,0.0369219847753799,"SMO/RREB1/VDR/PML/CSF1/GLI2/CEBPB",7]
[750,"up","up","GO:0050857","positive regulation of antigen receptor-mediated signaling pathway","4/604","25/18866",0.00770587814924056,0.0497342095730612,0.0376410194829397,"RELA/NFAM1/NECTIN2/ADA",4]
[751,"up","up","GO:0071677","positive regulation of mononuclear cell migration","4/604","25/18866",0.00770587814924056,0.0497342095730612,0.0376410194829397,"CXCL10/LGALS3/SERPINE1/FPR2",4]
[752,"up","up","GO:0009306","protein secretion","25/604","462/18866",0.00773764275702925,0.0498474066000731,0.0377266919312553,"IL1B/IL1RN/RAB13/CD14/MAFA/IL6/TLR8/BTN3A1/PCSK5/TRAF3IP2/EZR/APOE/PLEK/TGFB2/TLR2/BLK/RHBDF2/SLC8B1/CD40/MC4R/HCAR2/TCIRG1/GHSR/LCP2/CLEC5A",25]
[753,"up","up","GO:2000816","negative regulation of mitotic sister chromatid separation","5/604","39/18866",0.00774739656733658,0.0498474066000731,0.0377266919312553,"AURKB/NDC80/PLK1/BUB1/BUB1B",5]
[754,"up","up","GO:0007189","adenylate cyclase-activating G protein-coupled receptor signaling pathway","11/604","147/18866",0.00775426956394783,0.0498474066000731,0.0377266919312553,"ABCA1/GPR101/CXCL10/GPR65/ADM/LHCGR/ADM2/ADGRE1/MC1R/RAMP1/MC4R",11]