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{"sheet":"Table 3","index":0,"n_rows":3115,"n_cols":12,"rows_kept":3115,"merged":[[0,0,0,11]],"flags":["formulas_cached_only"]}
["Table 3. Significant DEGs in this study"]
["Gene id","MeanTPM (A)","MeanTPM (B)","log2FoldChange","pValue","qValue","result","GeneName","GeneDescription","GO","KEGG","KOG"]
["LOC101750367",0.0001,674.105591,22.68454316,0,0,"up","LOC101750367","-","GO:0008289","-","-"]
["LOC107051179",0.0001,243.325668,21.21445709,{"v":1.41e-128,"d":"1.41E-128"},{"v":1.12e-127,"d":"1.12E-127"},"up","LOC107051179","-","-","-","-"]
["DYDC1",0.0001,153.20993,20.54707838,0,0,"up","DYDC1","DPY30 domain containing 1","GO:0000781;GO:0006348;GO:0042800;GO:0048188;GO:0051568","-","-"]
["RSPH1",0.0001,140.383759,20.42094461,0,0,"up","RSPH1","-","GO:0000794;GO:0005737;GO:0007286;GO:0031514;GO:0035082;GO:0036126;GO:0072687","-","KOG0231-Junctional membrane complex protein Junctophilin and related MORN repeat proteins[R]"]
["CFAP126",0.0001,132.829453,20.34114365,{"v":3.31e-259,"d":"3.31E-259"},{"v":4.48e-258,"d":"4.48E-258"},"up","CFAP126","-","-","-","-"]
["EPYC",0.0001,122.311462,20.22212818,0,0,"up","EPYC","epiphycan","GO:0005576;GO:0005615;GO:0007409","-","KOG4237-Extracellular matrix protein slit, contains leucine-rich and EGF-like repeats[WT]"]
["LOC107055063",0.0001,61.436943,19.22874691,{"v":3.28e-82,"d":"3.28E-82"},{"v":1.94e-81,"d":"1.94E-81"},"up","LOC107055063","-","-","-","-"]
["FOLR1",0.0001,60.85564,19.21503145,{"v":5.08e-249,"d":"5.08E-249"},{"v":6.65e-248,"d":"6.65E-248"},"up","FOLR1","folate receptor 1","GO:0005542;GO:0061714;GO:0071231;GO:1904447","K13649-ko04144 Endocytosis","-"]
["MIR34C",0.0001,56.714725,19.11336383,{"v":1.04e-11,"d":"1.04E-11"},{"v":2.44e-11,"d":"2.44E-11"},"up","MIR34C","microRNA 34c","-","-","-"]
["CHIA-M31",0.0001,55.728817,19.088064,{"v":1.44e-241,"d":"1.44E-241"},{"v":1.85e-240,"d":"1.85E-240"},"up","CHIA-M31","-","GO:0004553;GO:0005576;GO:0005975;GO:0006030;GO:0008061","K01183-ko00520 Amino sugar and nucleotide sugar metabolism","-"]
["PPIL6",0.0001,54.3092,19.05083709,{"v":5.25e-171,"d":"5.25E-171"},{"v":5.13e-170,"d":"5.13E-170"},"up","PPIL6","-","GO:0000413;GO:0003755;GO:0016853","-","KOG0546-HSP90 co-chaperone CPR7/Cyclophilin[O]"]
["ANKRD1",0.0001,46.130203,18.81535212,0,0,"up","ANKRD1","ankyrin repeat domain 1","GO:0003712;GO:0005623;GO:0005634;GO:0005737;GO:0006357;GO:0007519;GO:0009791;GO:0010628;GO:0010629;GO:0014866;GO:0031432;GO:0031674;GO:0035914;GO:0043066;GO:0045445;GO:0051726;GO:0061629;GO:0071363;GO:2000288;GO:0001085;GO:0001650;GO:0002039;GO:0003677;GO:0003713;GO:0003714;GO:0005623;GO:0005634;GO:0005667;GO:0005737;GO:0005829;GO:0006357;GO:0007519;GO:0009791;GO:0010628;GO:0010629;GO:0014866;GO:0030016;GO:0031432;GO:0031674;GO:0035690;GO:0035914;GO:0035994;GO:0042826;GO:0043065;GO:0043066;GO:0043517;GO:0045445;GO:0050714;GO:0051726;GO:0055008;GO:0070412;GO:0071222;GO:0071260;GO:0071347;GO:0071356;GO:0071363;GO:0071560;GO:1903507;GO:1903508;GO:2000279;GO:2000288","-","KOG4177-Ankyrin[M]"]
["C7H21orf58",0.0001,43.674038,18.7364164,{"v":1.8e-191,"d":"1.80E-191"},{"v":1.91e-190,"d":"1.91E-190"},"up","C7H21orf58","-","-","-","-"]
["CFAP161",0.0001,40.363869,18.62270494,{"v":3.28e-160,"d":"3.28E-160"},{"v":3.06e-159,"d":"3.06E-159"},"up","CFAP161","-","-","-","-"]
["TEKT4",0.0001,34.922329,18.41379025,{"v":2.55e-177,"d":"2.55E-177"},{"v":2.56e-176,"d":"2.56E-176"},"up","TEKT4","-","GO:0005623;GO:0005634;GO:0030317;GO:0036126;GO:0060271;GO:0060294","-","KOG2685-Cystoskeletal protein Tektin[Z]"]
["DTHD1",0.0001,32.876659,18.32670417,{"v":4.1e-250,"d":"4.10E-250"},{"v":5.38e-249,"d":"5.38E-249"},"up","DTHD1","-","-","-","-"]
["CCDC33",0.0001,28.82234,18.13682794,{"v":2.23e-191,"d":"2.23E-191"},{"v":2.37e-190,"d":"2.37E-190"},"up","CCDC33","-","-","-","-"]
["PRR29",0.0001,27.440048,18.06592348,{"v":4.08e-240,"d":"4.08E-240"},{"v":5.18e-239,"d":"5.18E-239"},"up","PRR29","-","GO:0003841;GO:0006629;GO:0008152;GO:0008654;GO:0016020;GO:0016021;GO:0016740;GO:0016746","K13509-ko00561 Glycerolipid metabolism;ko00564 Glycerophospholipid metabolism;ko04072 Phospholipase D signaling pathway;ko04975 Fat digestion and absorption","-"]
["ZBBX",0.0001,26.563198,18.01906932,{"v":9.48e-202,"d":"9.48E-202"},{"v":1.05e-200,"d":"1.05E-200"},"up","ZBBX","-","-","-","-"]
["SAXO2",0.0001,26.47496,18.01426898,0,0,"up","SAXO2","-","GO:0008017","-","-"]
["LRRC46",0.0001,26.081606,17.99267318,{"v":7.65e-135,"d":"7.65E-135"},{"v":6.33e-134,"d":"6.33E-134"},"up","LRRC46","-","-","-","-"]
["CFAP77",0.0001,24.538666,17.9046973,{"v":4.93e-99,"d":"4.93E-99"},{"v":3.29e-98,"d":"3.29E-98"},"up","CFAP77","-","-","-","-"]
["RP1",0.0001,21.432343,17.70943005,{"v":3.76e-246,"d":"3.76E-246"},{"v":4.87e-245,"d":"4.87E-245"},"up","RP1","-","-","-","-"]
["CATIP",0.0001,21.245056,17.69676762,{"v":1.26e-96,"d":"1.26E-96"},{"v":8.28e-96,"d":"8.28E-96"},"up","CATIP","-","GO:0005634;GO:0005737;GO:0005886;GO:0015629;GO:0030041;GO:0044782","-","-"]
["LOC107052731",0.0001,20.430204,17.64034408,{"v":7.21e-92,"d":"7.21E-92"},{"v":4.58e-91,"d":"4.58E-91"},"up","LOC107052731","-","-","-","-"]
["PAX1",0.0001,19.701847,17.58797136,{"v":7.69e-126,"d":"7.69E-126"},{"v":6.04e-125,"d":"6.04E-125"},"up","PAX1","-","GO:0000978;GO:0001501;GO:0001756;GO:0003677;GO:0003700;GO:0005634;GO:0006351;GO:0006355;GO:0006366;GO:0007275;GO:0007389;GO:0008283;GO:0043367;GO:0043374;GO:0045944;GO:0048538;GO:0060017;GO:0060349;GO:0061056;GO:0003677;GO:0003700;GO:0005634;GO:0006351;GO:0006355;GO:0007275;GO:0061056","-","KOG3517-Transcription factor PAX1/9[K]"]
["TMEM213",0.0001,19.396309,17.56542262,{"v":3.38e-103,"d":"3.38E-103"},{"v":2.3e-102,"d":"2.30E-102"},"up","TMEM213","-","-","-","-"]
["TNNT2",0.0001,19.353653,17.56224638,{"v":1.21e-89,"d":"1.21E-89"},{"v":7.57e-89,"d":"7.57E-89"},"up","TNNT2","troponin T2, cardiac type","GO:0005861;GO:0006937","K12045-ko04260 Cardiac muscle contraction;ko04261 Adrenergic signaling in cardiomyocytes;ko05410 Hypertrophic cardiomyopathy (HCM);ko05414 Dilated cardiomyopathy (DCM)","KOG3634-Troponin[Z]"]
["CRABP1",0.0001,19.353119,17.56220657,{"v":3.88e-67,"d":"3.88E-67"},{"v":2.05e-66,"d":"2.05E-66"},"up","CRABP1","cellular retinoic acid binding protein 1","GO:0001972;GO:0005501;GO:0005623;GO:0005737;GO:0005829;GO:0008289;GO:0016918;GO:0019841;GO:0030424;GO:0034653;GO:0043005;GO:0070852","-","-"]
["TCP10",0.0001,17.780422,17.43993004,{"v":1.02e-237,"d":"1.02E-237"},{"v":1.28e-236,"d":"1.28E-236"},"up","TCP10","-","-","-","-"]
["LRRIQ1",0.0001,17.539444,17.42024349,{"v":1.29e-266,"d":"1.29E-266"},{"v":1.78e-265,"d":"1.78E-265"},"up","LRRIQ1","-","-","-","-"]
["RIBC2",0.0001,17.084484,17.38232715,{"v":1.22e-113,"d":"1.22E-113"},{"v":8.91e-113,"d":"8.91E-113"},"up","RIBC2","-","-","-","-"]
["LOC423629",0.0001,15.826398,17.27197342,{"v":5.34e-165,"d":"5.34E-165"},{"v":5.1e-164,"d":"5.10E-164"},"up","LOC423629","-","-","-","-"]
["ORM1",0.0001,15.754363,17.2653919,{"v":2.83e-55,"d":"2.83E-55"},{"v":1.35e-54,"d":"1.35E-54"},"up","ORM1","orosomucoid 1 (ovoglycoprotein)","-","-","-"]
["NHLRC4",0.0001,15.502332,17.24212573,{"v":1.54e-101,"d":"1.54E-101"},{"v":1.04e-100,"d":"1.04E-100"},"up","NHLRC4","-","-","-","-"]
["STMND1",0.0001,15.332284,17.2262131,{"v":5.5e-63,"d":"5.50E-63"},{"v":2.8e-62,"d":"2.80E-62"},"up","STMND1","-","-","-","-"]
["FOXI1",0.0001,13.45806,17.03811093,{"v":9.52e-121,"d":"9.52E-121"},{"v":7.26e-120,"d":"7.26E-120"},"up","FOXI1","-","GO:0000978;GO:0000981;GO:0003677;GO:0003700;GO:0005634;GO:0005730;GO:0006355;GO:0006366;GO:0009653;GO:0030154;GO:0042472;GO:0043231;GO:0043565;GO:0044212;GO:0045893;GO:0045944","-","KOG3562-Forkhead/HNF-3-related transcription factor[K]"]
["C6H10orf107",0.0001,13.425707,17.03463854,{"v":1.89e-57,"d":"1.89E-57"},{"v":9.19e-57,"d":"9.19E-57"},"up","C6H10orf107","-","-","-","-"]
["AKAP14",0.0001,12.920995,16.97935765,{"v":1.15e-47,"d":"1.15E-47"},{"v":5.09e-47,"d":"5.09E-47"},"up","AKAP14","-","-","-","-"]
["C12orf74",0.0001,11.874722,16.85753421,{"v":5.03e-88,"d":"5.03E-88"},{"v":3.11e-87,"d":"3.11E-87"},"up","C12orf74","-","-","-","-"]
["CFAP221",0.0001,11.841566,16.85350036,{"v":7.52e-125,"d":"7.52E-125"},{"v":5.88e-124,"d":"5.88E-124"},"up","CFAP221","-","GO:0003341;GO:0005516;GO:0005929;GO:0044458;GO:0060271","-","-"]
["DNAH5",0.0001,11.410992,16.80006469,0,0,"up","DNAH5","-","GO:0003341;GO:0003777;GO:0005524;GO:0005858;GO:0005930;GO:0007018;GO:0007368;GO:0007507;GO:0008569;GO:0016887;GO:0021670;GO:0030286;GO:0036157;GO:0036158;GO:0045503;GO:0045505;GO:0051959","-","KOG3595-Dyneins, heavy chain[Z]"]
["WDR78",0.0001,11.397696,16.79838269,{"v":5.79e-105,"d":"5.79E-105"},{"v":3.99e-104,"d":"3.99E-104"},"up","WDR78","-","GO:0002244","-","-"]
["TNIP3",0.0001,9.930213,16.59953704,{"v":6.94e-59,"d":"6.94E-59"},{"v":3.42e-58,"d":"3.42E-58"},"up","TNIP3","-","-","-","-"]
["LOC107052912",0.0001,9.76399,16.5751832,{"v":1.27e-91,"d":"1.27E-91"},{"v":8.05e-91,"d":"8.05E-91"},"up","LOC107052912","-","-","-","-"]
["CCDC180",0.0001,9.686346,16.56366492,{"v":2.49e-75,"d":"2.49E-75"},{"v":1.4e-74,"d":"1.40E-74"},"up","CCDC180","-","-","-","-"]
["SPAG8",0.0001,9.661006,16.5598858,{"v":1.25e-84,"d":"1.25E-84"},{"v":7.58e-84,"d":"7.58E-84"},"up","SPAG8","-","-","-","-"]
["LOC112529958",0.0001,9.40409,16.52100073,{"v":1.11e-38,"d":"1.11E-38"},{"v":4.37e-38,"d":"4.37E-38"},"up","LOC112529958","-","-","-","-"]
["MYH7B",0.0001,9.312181,16.50683148,{"v":8.62e-166,"d":"8.62E-166"},{"v":8.25e-165,"d":"8.25E-165"},"up","MYH7B","myosin, heavy chain 7B, cardiac muscle, beta","GO:0000166;GO:0003774;GO:0003779;GO:0005524;GO:0016459;GO:0051015;GO:0097512","K17751-ko04530 Tight junction;ko04260 Cardiac muscle contraction;ko04261 Adrenergic signaling in cardiomyocytes;ko05416 Viral myocarditis","KOG0161-Myosin class II heavy chain[Z]"]
["LOC100858131",0.0001,9.267096,16.4998297,{"v":1.4e-140,"d":"1.40E-140"},{"v":1.19e-139,"d":"1.19E-139"},"up","LOC100858131","-","-","-","-"]
["NKX2-1",0.0001,9.087315,16.47156647,{"v":3.48e-113,"d":"3.48E-113"},{"v":2.55e-112,"d":"2.55E-112"},"up","NKX2-1","NK2 homeobox 1","GO:0000122;GO:0000977;GO:0000978;GO:0000980;GO:0001012;GO:0001161;GO:0001764;GO:0003677;GO:0003700;GO:0005634;GO:0005667;GO:0006355;GO:0006357;GO:0006644;GO:0007389;GO:0007411;GO:0007420;GO:0007492;GO:0007626;GO:0009725;GO:0009887;GO:0010628;GO:0010719;GO:0019899;GO:0021537;GO:0021759;GO:0021766;GO:0021795;GO:0021798;GO:0021877;GO:0021879;GO:0021892;GO:0021895;GO:0021983;GO:0022029;GO:0030324;GO:0030336;GO:0030512;GO:0030878;GO:0030900;GO:0031128;GO:0033327;GO:0042753;GO:0043565;GO:0044212;GO:0044213;GO:0045892;GO:0045893;GO:0045944;GO:0048646;GO:0048663;GO:0048709;GO:0060430;GO:0060441;GO:0060486;GO:0060510","-","KOG0842-Transcription factor tinman/NKX2-3, contains HOX domain[K]"]
["LOC112531143",0.0001,9.023275,16.46136353,{"v":9.65e-21,"d":"9.65E-21"},{"v":2.84e-20,"d":"2.84E-20"},"up","LOC112531143","-","-","-","-"]
["MLN",0.0001,8.946972,16.44911188,{"v":6.97e-35,"d":"6.97E-35"},{"v":2.61e-34,"d":"2.61E-34"},"up","MLN","motilin","GO:0005179;GO:0005576;GO:0006939;GO:0010469;GO:0031788","K05265-ko04080 Neuroactive ligand-receptor interaction","-"]
["DEUP1",0.0001,8.883185,16.43878942,{"v":1.31e-73,"d":"1.31E-73"},{"v":7.25e-73,"d":"7.25E-73"},"up","DEUP1","-","GO:0042802;GO:0098535;GO:0098536;GO:1903251","-","-"]
["LOC112530945",0.0001,8.825009,16.42931013,{"v":5.13e-90,"d":"5.13E-90"},{"v":3.22e-89,"d":"3.22E-89"},"up","LOC112530945","-","-","-","-"]
["LOC101750822",0.0001,8.047578,16.29626703,{"v":9.28e-91,"d":"9.28E-91"},{"v":5.85e-90,"d":"5.85E-90"},"up","LOC101750822","-","-","-","-"]
["LOC107050903",0.0001,7.95995,16.28047175,{"v":1.93e-81,"d":"1.93E-81"},{"v":1.13e-80,"d":"1.13E-80"},"up","LOC107050903","-","-","-","-"]
["LOC107051778",0.0001,7.950846,16.27882076,{"v":1.42e-19,"d":"1.42E-19"},{"v":4.07e-19,"d":"4.07E-19"},"up","LOC107051778","-","-","-","-"]
["LOC425001",0.0001,7.949319,16.27854365,{"v":1.17e-64,"d":"1.17E-64"},{"v":6.04e-64,"d":"6.04E-64"},"up","LOC425001","-","-","-","-"]
["MIR34B",0.0001,7.815852,16.25411553,0.005979232,0.008557407,"up","MIR34B","microRNA 34b","-","-","-"]
["R3HDML",0.0001,7.800204,16.25122424,{"v":1.95e-46,"d":"1.95E-46"},{"v":8.49e-46,"d":"8.49E-46"},"up","R3HDML","-","-","-","KOG3017-Defense-related protein containing SCP domain[S]"]
["FAM81B",0.0001,7.50617,16.19578934,{"v":2.68e-77,"d":"2.68E-77"},{"v":1.53e-76,"d":"1.53E-76"},"up","FAM81B","-","-","-","-"]
["ACSS1L",0.0001,7.088132,16.11311785,{"v":1.22e-68,"d":"1.22E-68"},{"v":6.54e-68,"d":"6.54E-68"},"up","ACSS1L","-","GO:0000166;GO:0003824;GO:0003987;GO:0005524;GO:0008152;GO:0016208;GO:0016874;GO:0019427","K01895-ko01200 Carbon metabolism;ko00010 Glycolysis / Gluconeogenesis;ko00620 Pyruvate metabolism;ko00640 Propanoate metabolism;ko00720 Carbon fixation pathways in prokaryotes;ko00680 Methane metabolism","-"]
["LOC107052722",0.0001,6.84119,16.06195968,{"v":5.49e-26,"d":"5.49E-26"},{"v":1.79e-25,"d":"1.79E-25"},"up","LOC107052722","-","-","-","-"]
["WHRN",0.0001,6.326585,15.94913934,{"v":1.14e-80,"d":"1.14E-80"},{"v":6.66e-80,"d":"6.66E-80"},"up","WHRN","-","-","-","KOG3542-cAMP-regulated guanine nucleotide exchange factor[T]"]
["LOC100857543",0.0001,6.196145,15.91908329,{"v":2.48e-39,"d":"2.48E-39"},{"v":9.89e-39,"d":"9.89E-39"},"up","LOC100857543","-","-","-","-"]
["LOC112532702",0.0001,6.022843,15.87815703,{"v":1.27e-25,"d":"1.27E-25"},{"v":4.11e-25,"d":"4.11E-25"},"up","LOC112532702","-","-","-","-"]
["BSND",0.0001,5.821656,15.82914197,{"v":1.64e-32,"d":"1.64E-32"},{"v":5.97e-32,"d":"5.97E-32"},"up","BSND","-","GO:0005254;GO:0005887;GO:0006821;GO:0016020;GO:0016021;GO:0016323;GO:0032991;GO:1902476","-","-"]
["PP2D1",0.0001,5.658271,15.78807366,{"v":1.1e-63,"d":"1.10E-63"},{"v":5.65e-63,"d":"5.65E-63"},"up","PP2D1","-","GO:0003824;GO:0004722;GO:0006470","-","KOG0698-Serine/threonine protein phosphatase[T]"]
["LOC112532987",0.0001,5.582549,15.76863639,{"v":1.03e-34,"d":"1.03E-34"},{"v":3.84e-34,"d":"3.84E-34"},"up","LOC112532987","-","-","-","-"]
["FAM187A",0.0001,5.567774,15.76481303,{"v":2.98e-27,"d":"2.98E-27"},{"v":9.92e-27,"d":"9.92E-27"},"up","FAM187A","-","-","-","-"]
["WDR63",0.0001,5.488427,15.74410511,{"v":5e-116,"d":"5.00E-116"},{"v":3.72e-115,"d":"3.72E-115"},"up","WDR63","-","GO:0007018;GO:0008574;GO:0030286;GO:0045503;GO:0045504","-","KOG1587-Cytoplasmic dynein intermediate chain[Z]"]
["TRPV4",0.0001,5.425405,15.72744322,{"v":4.29e-68,"d":"4.29E-68"},{"v":2.28e-67,"d":"2.28E-67"},"up","TRPV4","transient receptor potential cation channel subfamily V member 4","GO:0000122;GO:0000166;GO:0002024;GO:0005034;GO:0005216;GO:0005261;GO:0005262;GO:0005516;GO:0005524;GO:0005886;GO:0005912;GO:0005929;GO:0006811;GO:0006816;GO:0006874;GO:0006970;GO:0007043;GO:0007204;GO:0007231;GO:0008289;GO:0010628;GO:0010759;GO:0015275;GO:0016020;GO:0016021;GO:0016324;GO:0019901;GO:0030054;GO:0030103;GO:0032868;GO:0034605;GO:0042169;GO:0042538;GO:0042593;GO:0042802;GO:0043117;GO:0046330;GO:0046872;GO:0047484;GO:0050729;GO:0050891;GO:0055085;GO:0060351;GO:0070374;GO:0070509;GO:0070588;GO:0071470;GO:0071476;GO:0071477;GO:0071639;GO:0071642;GO:0071651;GO:0097009;GO:0097497;GO:1903444;GO:1903759;GO:2000340;GO:2000778","K04973-ko04750 Inflammatory mediator regulation of TRP channels","-"]
["CCDC89",0.0001,5.269496,15.68537736,{"v":1.02e-35,"d":"1.02E-35"},{"v":3.86e-35,"d":"3.86E-35"},"up","CCDC89","-","-","-","-"]
["C4H4ORF47",0.0001,5.204067,15.66735192,{"v":1.64e-32,"d":"1.64E-32"},{"v":5.97e-32,"d":"5.97E-32"},"up","C4H4ORF47","-","GO:0005813","-","-"]
["LOC112530790",0.0001,5.006778,15.61159487,{"v":4.37e-05,"d":"4.37E-05"},{"v":7.47e-05,"d":"7.47E-05"},"up","LOC112530790","-","-","-","-"]
["SFTPA2",0.094901,2644.837891,14.76639648,0,0,"up","SFTPA2","surfactant protein A2","-","K10067-ko04145 Phagosome;ko05133 Pertussis","-"]
["BPIL3",0.265818,3855.435547,13.82416743,0,0,"up","BPIL3","-","GO:0008289","-","-"]
["LOC101750711",0.004849,11.761502,11.24409744,{"v":4.82e-136,"d":"4.82E-136"},{"v":4e-135,"d":"4.00E-135"},"up","LOC101750711","-","-","-","-"]
["FGB",0.144441,275.732971,10.89857576,0,0,"up","FGB","fibrinogen beta chain","GO:0005102;GO:0005198;GO:0005576;GO:0005577;GO:0005615;GO:0005783;GO:0005938;GO:0007160;GO:0007596;GO:0007599;GO:0009897;GO:0009986;GO:0030168;GO:0030674;GO:0031091;GO:0031639;GO:0034116;GO:0034622;GO:0042730;GO:0043152;GO:0045202;GO:0045907;GO:0045921;GO:0046872;GO:0050714;GO:0050839;GO:0051087;GO:0051258;GO:0051592;GO:0070374;GO:0070527;GO:0072378;GO:0090277;GO:1902042;GO:2000352","-","KOG2579-Ficolin and related extracellular proteins[R]"]
["C11orf88",0.121106,219.028168,10.82063036,0,0,"up","C11orf88","-","-","-","-"]
["FOXJ1",0.098525,150.140793,10.57353854,0,0,"up","FOXJ1","forkhead box J1","GO:0000122;GO:0000976;GO:0000978;GO:0002508;GO:0002635;GO:0002897;GO:0002924;GO:0003677;GO:0003700;GO:0005634;GO:0006355;GO:0006366;GO:0006959;GO:0007368;GO:0007420;GO:0007507;GO:0030036;GO:0030856;GO:0032088;GO:0033085;GO:0035089;GO:0035502;GO:0042130;GO:0043565;GO:0044458;GO:0045409;GO:0045944;GO:0050869;GO:0050900;GO:0060271;GO:0060428;GO:0060429;GO:0060972;GO:0072016;GO:0090630;GO:1901248","-","KOG3563-Forkhead/HNF-3-related transcription factor[K]"]
["CFAP65",0.013537,17.668154,10.35002755,0,0,"up","CFAP65","-","GO:0005886;GO:0005929;GO:0016020;GO:0016021;GO:0031514;GO:0042995","-","-"]
["ACAN",0.19706,254.509949,10.33487138,0,0,"up","ACAN","aggrecan","GO:0001501;GO:0005201;GO:0005509;GO:0005540;GO:0005576;GO:0007155;GO:0007417;GO:0030246;GO:0046872;GO:0001502;GO:0002063;GO:0005509;GO:0005540;GO:0005604;GO:0007155;GO:0007507;GO:0030166;GO:0030199;GO:0031012;GO:0098966;GO:0098978;GO:0098982","-","-"]
["DRC7",0.028034,29.933817,10.06038293,0,0,"up","DRC7","-","GO:0005737","-","-"]
["MATN1",0.476659,486.565033,9.995459393,0,0,"up","MATN1","matrilin 1, cartilage matrix protein","GO:0005201;GO:0005509;GO:0005576;GO:0062023;GO:0002062;GO:0003429;GO:0005201;GO:0005509;GO:0030500;GO:0031012;GO:0062023","-","KOG1214-Nidogen and related basement membrane protein proteins[MW]"]
["CFAP44",0.011083,11.168175,9.976829288,{"v":5.07e-294,"d":"5.07E-294"},{"v":7.58e-293,"d":"7.58E-293"},"up","CFAP44","-","-","-","[KOG2106-Uncharacterized conserved protein, contains HELP and WD40 domains[S], KOG0263-Transcription initiation factor TFIID, subunit TAF5 (also component of histone acetyltransferase SAGA)[K]]"]
["CFAP52",0.033607,33.058853,9.942059192,{"v":5.38e-305,"d":"5.38E-305"},{"v":8.26e-304,"d":"8.26E-304"},"up","CFAP52","-","-","-","-"]
["SNTN",0.384978,373.647095,9.922684587,0,0,"up","SNTN","sentan, cilia apical structure protein","GO:0046914;GO:0005929;GO:0042995;GO:0046914","-","-"]
["MYL3",1.112833,863.513672,9.599838103,0,0,"up","MYL3","myosin, light chain 3, alkali; ventricular, skeletal, slow","GO:0002026;GO:0003785;GO:0005509;GO:0006942;GO:0031672;GO:0031674;GO:0055010;GO:0060048","K12749-ko04260 Cardiac muscle contraction;ko04261 Adrenergic signaling in cardiomyocytes;ko05410 Hypertrophic cardiomyopathy (HCM);ko05414 Dilated cardiomyopathy (DCM)","KOG0030-Myosin essential light chain, EF-Hand protein superfamily[Z]"]
["LOC101750892",3.002675,2173.810791,9.499762327,0,0,"up","LOC101750892","-","-","-","-"]
["CCDC146",0.047545,33.458584,9.458867045,0,0,"up","CCDC146","-","-","-","-"]
["DRC1",0.037311,24.112795,9.335982146,{"v":1.27e-242,"d":"1.27E-242"},{"v":1.63e-241,"d":"1.63E-241"},"up","DRC1","-","GO:0007368;GO:0007507;GO:0060285;GO:0070286","-","-"]
["LOC112532700",1.39539,884.816223,9.308565627,0,0,"up","LOC112532700","-","-","-","-"]
["COL9A2",1.809751,952.941162,9.040452116,0,0,"up","COL9A2","collagen type IX alpha 2 chain","GO:0005576;GO:0005581;GO:0005594","K08131-ko04151 PI3K-Akt signaling pathway;ko04512 ECM-receptor interaction;ko04510 Focal adhesion;ko04974 Protein digestion and absorption","-"]
["ENKUR",0.224172,116.845192,9.025776564,0,0,"up","ENKUR","-","GO:0001669;GO:0005516;GO:0097228","-","-"]
["C18H17ORF67",2.037495,1052.553711,9.01288162,0,0,"up","C18H17ORF67","chromosome 18 open reading frame, human C17orf67","-","-","-"]
["SLC23A1",0.03805,19.131815,8.973861577,{"v":7.57e-198,"d":"7.57E-198"},{"v":8.18e-197,"d":"8.18E-197"},"up","SLC23A1","-","GO:0005737;GO:0005886;GO:0006814;GO:0007420;GO:0008520;GO:0009636;GO:0009925;GO:0015081;GO:0015229;GO:0015882;GO:0016020;GO:0016021;GO:0016324;GO:0022857;GO:0030324;GO:0033300;GO:0035725;GO:0043229;GO:0055085;GO:0070837;GO:0070890;GO:0070904","-","KOG1292-Xanthine/uracil transporters[F]"]
["TNNT1",1.23912,610.761169,8.945148622,0,0,"up","TNNT1","troponin T1, slow skeletal type","GO:0003009;GO:0005523;GO:0005861;GO:0006937;GO:0045932","-","-"]
["DAW1",0.136381,65.019173,8.897078727,0,0,"up","DAW1","-","GO:0005737;GO:0007368;GO:0007507","-","[KOG0274-Cdc4 and related F-box and WD-40 proteins[R], KOG0271-Notchless-like WD40 repeat-containing protein[S]]"]
["COL2A1",6.730332,3198.059082,8.892303203,0,0,"up","COL2A1","collagen type II alpha 1 chain","GO:0005201;GO:0005576;GO:0005581;GO:0046872","K19719-ko04151 PI3K-Akt signaling pathway;ko04512 ECM-receptor interaction;ko04510 Focal adhesion;ko04974 Protein digestion and absorption","KOG3546-Collagens (type XV)[W]"]
["NSUN7",0.040078,17.85652,8.799424714,0,0,"up","NSUN7","-","GO:0003723;GO:0008168;GO:0016740;GO:0032259","-","KOG2360-Proliferation-associated nucleolar protein  (NOL1)[D]"]
["COL9A1",2.299808,962.439209,8.709038185,0,0,"up","COL9A1","collagen type IX alpha 1 chain","GO:0005576;GO:0005581;GO:0005594","K08131-ko04151 PI3K-Akt signaling pathway;ko04512 ECM-receptor interaction;ko04510 Focal adhesion;ko04974 Protein digestion and absorption","-"]
["CHIA",1.967247,812.556641,8.690146464,0,0,"up","CHIA","chitinase, acidic","GO:0004553;GO:0004568;GO:0005576;GO:0005737;GO:0005975;GO:0006030;GO:0006032;GO:0008061","K01183-ko00520 Amino sugar and nucleotide sugar metabolism","KOG2806-Chitinase[G]"]
["LOC112529943",3.528051,1434.313599,8.667273359,0,0,"up","LOC112529943","-","-","-","-"]
["ARMC4",0.070284,27.914988,8.63362792,0,0,"up","ARMC4","-","GO:0003341;GO:0003356;GO:0005634;GO:0005737;GO:0005930;GO:0007368;GO:0007507;GO:0021591;GO:0036158;GO:0097546","-","KOG4224-Armadillo repeat protein VAC8 required for vacuole fusion, inheritance and cytosol-to-vacuole protein targeting[U]"]
["CFAP45",0.101661,39.442341,8.599835044,0,0,"up","CFAP45","-","GO:0005654","-","-"]
["TSGA10",0.038703,14.883035,8.587007642,{"v":2.74e-261,"d":"2.74E-261"},{"v":3.73e-260,"d":"3.73E-260"},"up","TSGA10","-","-","-","-"]
["LOC427533",0.44095,151.103668,8.420707891,0,0,"up","LOC427533","-","GO:0005509;GO:0016020;GO:0016021","-","-"]
["LOC112533535",0.657064,215.467178,8.357218506,0,0,"up","LOC112533535","-","-","-","-"]
["COL9A3",1.17179,376.111359,8.326302025,0,0,"up","COL9A3","collagen type IX alpha 3 chain","GO:0005576;GO:0005581;GO:0005594;GO:0008584;GO:0008585","K08131-ko04151 PI3K-Akt signaling pathway;ko04512 ECM-receptor interaction;ko04510 Focal adhesion;ko04974 Protein digestion and absorption","-"]
["ADGB",0.079473,23.698378,8.220107799,0,0,"up","ADGB","-","GO:0004198;GO:0005622;GO:0005737;GO:0006508;GO:0019825;GO:0020037","-","-"]
["LOC418355",0.038478,11.158832,8.179936499,{"v":6.85e-71,"d":"6.85E-71"},{"v":3.73e-70,"d":"3.73E-70"},"up","LOC418355","-","-","-","-"]
["USH1C",0.052479,14.70012,8.129871987,{"v":6.69e-238,"d":"6.69E-238"},{"v":8.44e-237,"d":"8.44E-237"},"up","USH1C","-","GO:0000086;GO:0005737;GO:0005829;GO:0005902;GO:0005903;GO:0007605;GO:0030507;GO:0034622;GO:0045177;GO:0045494;GO:0050953;GO:0050957;GO:0051015;GO:1904106;GO:1904970","-","KOG3549-Syntrophins (type gamma)[W]"]
["CLEC3A",0.593884,164.533691,8.11398615,0,0,"up","CLEC3A","C-type lectin domain family 3 member A","-","-","-"]
["LOC107053870",0.01944,5.290385,8.088200687,{"v":5.8e-61,"d":"5.80E-61"},{"v":2.9e-60,"d":"2.90E-60"},"up","LOC107053870","-","-","-","-"]
["FHAD1",0.051649,13.155695,7.992731334,0,0,"up","FHAD1","-","-","-","-"]
["C11orf63",0.066835,16.687771,7.963971742,{"v":4.03e-219,"d":"4.03E-219"},{"v":4.78e-218,"d":"4.78E-218"},"up","C11orf63","-","-","-","-"]
["DNAH5L",0.046303,11.402045,7.943971215,0,0,"up","DNAH5L","-","GO:0003341;GO:0003777;GO:0005524;GO:0007018;GO:0008569;GO:0016887;GO:0030286;GO:0036157;GO:0036158;GO:0045503;GO:0045505;GO:0051959","-","-"]
["MB",3.175256,766.348206,7.914983337,0,0,"up","MB","myoglobin","GO:0001666;GO:0005344;GO:0007507;GO:0015671;GO:0019825;GO:0020037;GO:0043353;GO:0046872","-","-"]
["LOC112530621",0.193458,44.346527,7.840656925,{"v":1.48e-263,"d":"1.48E-263"},{"v":2.02e-262,"d":"2.02E-262"},"up","LOC112530621","-","-","-","-"]
["C1QTNF8",0.349292,78.686852,7.815545181,0,0,"up","C1QTNF8","-","GO:0005576;GO:0005581","-","-"]
["MOV10L1",0.116881,25.665873,7.778667096,0,0,"up","MOV10L1","-","-","-","KOG1804-RNA helicase[A]"]
["DNAH10",0.045651,9.853121,7.753790501,0,0,"up","DNAH10","-","-","-","KOG3595-Dyneins, heavy chain[Z]"]
["SMYD1",0.622322,128.342804,7.688125444,0,0,"up","SMYD1","SET and MYND domain containing 1","GO:0003714;GO:0005634;GO:0005737;GO:0006338;GO:0007507;GO:0010831;GO:0035914;GO:0045663;GO:0045892","-","KOG2084-Predicted histone tail methylase containing SET domain[B]"]
["CCDC153",0.291886,59.998192,7.683370201,0,0,"up","CCDC153","-","-","-","-"]
["LOC107055922",0.151959,31.165346,7.680116796,0,0,"up","LOC107055922","-","-","-","-"]
["CYTL1",1.823322,362.802338,7.636470578,0,0,"up","CYTL1","-","GO:0002062;GO:0045944;GO:0048839;GO:0050650;GO:0051091;GO:1990079","-","-"]
["FAM183A",0.463934,91.389,7.621957136,{"v":3.13e-296,"d":"3.13E-296"},{"v":4.71e-295,"d":"4.71E-295"},"up","FAM183A","family with sequence similarity 183 member A","-","-","-"]
["LRGUK",0.103549,20.160654,7.605085008,0,0,"up","LRGUK","-","GO:0001669;GO:0002177;GO:0007283;GO:0035082","-","KOG0707-Guanylate kinase[F]"]
["HPS5",36.359421,6970.8125,7.582853787,0,0,"up","HPS5","-","GO:0005576;GO:0005615;GO:0006953;GO:0034364;GO:0042056;GO:0050918;GO:0060326","-","KOG3621-WD40 repeat-containing protein[R]"]
["PLEKHG7",0.215407,40.960438,7.571022199,0,0,"up","PLEKHG7","-","GO:0005085;GO:0005089;GO:0005622;GO:0035023;GO:0035556","-","KOG3521-Predicted guanine nucleotide exchange factor[T]"]
["MYL10",1.072209,203.645096,7.569327113,0,0,"up","MYL10","myosin, light chain 10, regulatory","GO:0005509;GO:0005739","K12756-ko04810 Regulation of actin cytoskeleton;ko04510 Focal adhesion;ko04530 Tight junction;ko04670 Leukocyte transendothelial migration","KOG0031-Myosin regulatory light chain, EF-Hand protein superfamily[Z]"]
["CFAP99",0.106711,20.114273,7.558366885,{"v":8e-257,"d":"8.00E-257"},{"v":1.07e-255,"d":"1.07E-255"},"up","CFAP99","-","-","-","-"]
["LOC428383",0.110955,20.523958,7.531190486,{"v":3.97e-86,"d":"3.97E-86"},{"v":2.43e-85,"d":"2.43E-85"},"up","LOC428383","-","-","-","-"]
["ZNF385C",0.03625,6.366509,7.456377699,{"v":7.24e-160,"d":"7.24E-160"},{"v":6.74e-159,"d":"6.74E-159"},"up","ZNF385C","-","GO:0002039;GO:0003676;GO:0003723;GO:0005622;GO:0008270;GO:0046872;GO:0072332","-","-"]
["UTS2R",0.088849,15.410402,7.438333243,{"v":1.63e-215,"d":"1.63E-215"},{"v":1.9e-214,"d":"1.90E-214"},"up","UTS2R","-","GO:0001604;GO:0004930;GO:0005887;GO:0007165;GO:0007186;GO:0007200;GO:0007218;GO:0008217;GO:0016020;GO:0016021;GO:0097746","K04241-ko04080 Neuroactive ligand-receptor interaction","-"]
["LOC768786",0.485099,82.880013,7.416601214,0,0,"up","LOC768786","-","GO:0004553;GO:0005975;GO:0008061","K01183-ko00520 Amino sugar and nucleotide sugar metabolism","-"]
["FBXL13",0.074318,12.508547,7.394986822,{"v":5.31e-203,"d":"5.31E-203"},{"v":5.93e-202,"d":"5.93E-202"},"up","FBXL13","-","-","-","-"]
["C1QTNF4",0.197299,32.888058,7.381036367,{"v":2.09e-285,"d":"2.09E-285"},{"v":3.03e-284,"d":"3.03E-284"},"up","C1QTNF4","-","GO:0005615;GO:0032755;GO:0070105;GO:1901224;GO:1904469;GO:2000778","-","-"]
["VIT",1.164519,189.604782,7.347117362,0,0,"up","VIT","vitrin","GO:0005539;GO:0005614;GO:0010811;GO:0021510;GO:0030198;GO:0031012;GO:0062023","-","-"]
["AK7",0.137189,22.104855,7.332054652,0,0,"up","AK7","-","GO:0004017;GO:0004127;GO:0004550;GO:0005524;GO:0006139;GO:0006165;GO:0009142;GO:0019205;GO:0046940","K00939-ko00230 Purine metabolism","KOG3078-Adenylate kinase[F]"]
["AK8",0.116769,18.643229,7.318850629,{"v":2.38e-147,"d":"2.38E-147"},{"v":2.09e-146,"d":"2.09E-146"},"up","AK8","-","GO:0004017;GO:0004127;GO:0004550;GO:0005524;GO:0005930;GO:0006139;GO:0006165;GO:0009142;GO:0016301;GO:0016310;GO:0016740;GO:0019205;GO:0021591;GO:0036126;GO:0046940","K00939-ko00230 Purine metabolism","-"]
["LOC112529936",0.067249,10.653004,7.307531778,{"v":1.35e-154,"d":"1.35E-154"},{"v":1.22e-153,"d":"1.22E-153"},"up","LOC112529936","-","-","-","-"]
["CNMD",2.096861,329.955536,7.297896584,0,0,"up","CNMD","chondromodulin","GO:0005576;GO:0007275;GO:0012505;GO:0016020;GO:0016021;GO:0030154;GO:0051216;GO:0016020;GO:0016021;GO:0016525","-","-"]
["GMNC",0.055031,8.533448,7.276740435,{"v":1.24e-218,"d":"1.24E-218"},{"v":1.47e-217,"d":"1.47E-217"},"up","GMNC","-","-","-","-"]
["PTX3",0.106713,16.348782,7.259303408,{"v":8.1e-145,"d":"8.10E-145"},{"v":7.03e-144,"d":"7.03E-144"},"up","PTX3","pentraxin 3","GO:0001849;GO:0001872;GO:0001878;GO:0005576;GO:0005615;GO:0008228;GO:0042802;GO:0044869;GO:0044871;GO:0045087;GO:0045429;GO:0046597;GO:0046790;GO:0046872;GO:0050766;GO:1903016;GO:1903019","-","-"]
["RAB36",0.203577,30.920286,7.246835278,0,0,"up","RAB36","-","GO:0003924;GO:0005525","-","KOG0094-GTPase Rab6/YPT6/Ryh1, small G protein superfamily[U]"]
["DNAI2",0.270437,41.067951,7.24657661,0,0,"up","DNAI2","-","GO:0003341;GO:0003777;GO:0005858;GO:0005930;GO:0007368;GO:0008574;GO:0009897;GO:0036126;GO:0036157;GO:0036158;GO:0045503;GO:0045504;GO:0060271","-","-"]
["IQCA1",0.086367,13.072189,7.241804854,{"v":2.98e-241,"d":"2.98E-241"},{"v":3.81e-240,"d":"3.81E-240"},"up","IQCA1","-","GO:0005524","-","KOG0740-AAA+-type ATPase[O]"]
["C1H3ORF30",0.067465,9.759974,7.17659425,{"v":2.33e-64,"d":"2.33E-64"},{"v":1.2e-63,"d":"1.20E-63"},"up","C1H3ORF30","-","-","-","-"]
["LOC107049033",0.085497,12.287354,7.167084761,{"v":6.02e-234,"d":"6.02E-234"},{"v":7.51e-233,"d":"7.51E-233"},"up","LOC107049033","-","-","-","-"]
["LOC112531906",0.076654,10.582826,7.109148138,{"v":8.25e-126,"d":"8.25E-126"},{"v":6.48e-125,"d":"6.48E-125"},"up","LOC112531906","-","-","-","-"]
["AGBL2",0.247902,33.379131,7.073032675,0,0,"up","AGBL2","-","GO:0004181;GO:0005814;GO:0005829;GO:0006508;GO:0008270;GO:0035610;GO:0036064","-","-"]
["WDR66",0.100733,13.096279,7.022476766,{"v":4.01e-243,"d":"4.01E-243"},{"v":5.16e-242,"d":"5.16E-242"},"up","WDR66","-","-","-","-"]
["KLHL34",0.273022,35.456234,7.02087829,0,0,"up","KLHL34","-","GO:0004842;GO:0016567;GO:0031463","-","KOG4441-Proteins containing BTB/POZ and Kelch domains, involved in regulatory/signal transduction processes[TR]"]
["TPCN2",6.149909,771.237122,6.970465621,0,0,"up","TPCN2","-","GO:0005216;GO:0005245;GO:0005764;GO:0005765;GO:0005886;GO:0006811;GO:0006816;GO:0006874;GO:0006939;GO:0007040;GO:0010008;GO:0010506;GO:0016020;GO:0016021;GO:0019722;GO:0019901;GO:0042802;GO:0051209;GO:0055085;GO:0072345;GO:0086010","-","KOG2302-T-type voltage-gated Ca2+ channel, pore-forming alpha1I subunit[PT]"]
["LRRC6",0.195366,24.115025,6.947609082,{"v":2.17e-202,"d":"2.17E-202"},{"v":2.42e-201,"d":"2.42E-201"},"up","LRRC6","leucine rich repeat containing 6","GO:0003341;GO:0005737;GO:0005929;GO:0008584;GO:0030317;GO:0036158;GO:0036159;GO:0044458;GO:0060287;GO:0061458","-","KOG1644-U2-associated snRNP A' protein[A]"]
["SDR42E2L",0.044399,5.476662,6.946625852,{"v":5.96e-134,"d":"5.96E-134"},{"v":4.9e-133,"d":"4.90E-133"},"up","SDR42E2L","-","GO:0003854;GO:0006694;GO:0016020;GO:0016021;GO:0016616;GO:0055114","-","-"]
["DNAH7",0.11417,14.077132,6.946026017,0,0,"up","DNAH7","-","GO:0003341;GO:0003777;GO:0005509;GO:0005524;GO:0005829;GO:0005929;GO:0007018;GO:0008569;GO:0030286;GO:0036156;GO:0036159;GO:0045503;GO:0045505;GO:0051959","-","-"]
["ROPN1L",0.695844,82.814308,6.894972329,0,0,"up","ROPN1L","-","GO:0001932;GO:0003341;GO:0005737;GO:0005929;GO:0030317;GO:0031514;GO:0048240","-","-"]
["LYG2",5.009725,595.012207,6.892044045,0,0,"up","LYG2","lysozyme g2","GO:0003796;GO:0008152;GO:0009253;GO:0016787;GO:0016798;GO:0016998","-","-"]
["ACOT4",0.084852,9.752366,6.844659795,{"v":3.32e-10,"d":"3.32E-10"},{"v":7.33e-10,"d":"7.33E-10"},"up","ACOT4","-","GO:0006637;GO:0016790","K01068-ko00062 Fatty acid elongation;ko01040 Biosynthesis of unsaturated fatty acids","-"]
["LOC107052568",0.065148,7.318897,6.811761543,{"v":1.37e-101,"d":"1.37E-101"},{"v":9.26e-101,"d":"9.26E-101"},"up","LOC107052568","-","-","-","-"]
["REEP6",0.34146,37.855907,6.792658039,{"v":8.98e-171,"d":"8.98E-171"},{"v":8.77e-170,"d":"8.77E-170"},"up","REEP6","-","GO:0016020;GO:0016021","-","KOG1725-Protein involved in membrane traffic (YOP1/TB2/DP1/HVA22 family)[U]"]
["COL11A1",3.082056,335.244537,6.765176937,0,0,"up","COL11A1","-","-","-","-"]
["LOC107054212",0.123233,13.002279,6.721232066,{"v":3.1e-68,"d":"3.10E-68"},{"v":1.65e-67,"d":"1.65E-67"},"up","LOC107054212","-","-","-","-"]
["SHISA3",0.070383,7.425013,6.721022733,{"v":1.79e-103,"d":"1.79E-103"},{"v":1.22e-102,"d":"1.22E-102"},"up","SHISA3","-","GO:0016020;GO:0016021","-","-"]
["AK9",0.062836,6.566952,6.707488755,{"v":1.36e-201,"d":"1.36E-201"},{"v":1.51e-200,"d":"1.51E-200"},"up","AK9","-","GO:0004550;GO:0005524;GO:0005634;GO:0005654;GO:0005737;GO:0006139;GO:0006174;GO:0006186;GO:0006756;GO:0006757;GO:0019205;GO:0031965;GO:0050145;GO:0061508;GO:0061565;GO:0061566;GO:0061567;GO:0061568;GO:0061569;GO:0061570;GO:0061571","K18533-ko00230 Purine metabolism;ko00240 Pyrimidine metabolism","-"]
["FRMPD2",0.207653,21.261833,6.677947453,0,0,"up","FRMPD2","-","-","-","-"]
["CSRP3",3.486615,338.517212,6.601258312,0,0,"up","CSRP3","cysteine and glycine rich protein 3","GO:0002026;GO:0003300;GO:0006874;GO:0008307;GO:0030018;GO:0031433;GO:0033365;GO:0035995;GO:0042802;GO:0042805;GO:0045944;GO:0046872;GO:0048738;GO:0055003;GO:0060048","-","KOG1700-Regulatory protein MLP and related LIM proteins[TZ]"]
["CA3A",0.096588,9.307395,6.590389664,{"v":6.4e-114,"d":"6.40E-114"},{"v":4.7e-113,"d":"4.70E-113"},"up","CA3A","carbonic anhydrase 3A","GO:0004089;GO:0005623;GO:0005737;GO:0008270;GO:0046872","K01672-ko00910 Nitrogen metabolism","KOG0382-Carbonic anhydrase[R]"]
["XIRP1",0.185948,17.68602,6.571566384,0,0,"up","XIRP1","xin actin-binding repeat containing 1","GO:0003779;GO:0007507;GO:0030036;GO:0030054","-","-"]
["TNNI1",3.610834,338.362915,6.550095549,0,0,"up","TNNI1","-","GO:0003009;GO:0005861;GO:0014883;GO:0055010;GO:0060048","-","KOG3977-Troponin I[Z]"]
["CFAP61",0.085606,7.921968,6.532003147,{"v":5.46e-171,"d":"5.46E-171"},{"v":5.34e-170,"d":"5.34E-170"},"up","CFAP61","-","-","-","-"]
["ATP6V1G3",0.136568,12.255048,6.487612847,{"v":3.13e-45,"d":"3.13E-45"},{"v":1.35e-44,"d":"1.35E-44"},"up","ATP6V1G3","-","GO:0005829;GO:0005886;GO:0006811;GO:0008553;GO:0016471;GO:0042626;GO:0051117;GO:1902600","K02152-ko00190 Oxidative phosphorylation;ko04150 mTOR signaling pathway;ko04145 Phagosome;ko04966 Collecting duct acid secretion;ko04721 Synaptic vesicle cycle;ko05323 Rheumatoid arthritis;ko05110 Vibrio cholerae infection;ko05120 Epithelial cell signaling in Helicobacter pylori infection","KOG1772-Vacuolar H+-ATPase V1 sector, subunit G[C]"]
["DLX2",0.126427,11.124616,6.459307126,{"v":7.22e-66,"d":"7.22E-66"},{"v":3.75e-65,"d":"3.75E-65"},"up","DLX2","-","GO:0000122;GO:0000977;GO:0001228;GO:0003677;GO:0003682;GO:0003727;GO:0005634;GO:0006355;GO:0006357;GO:0006366;GO:0009954;GO:0021544;GO:0021766;GO:0021772;GO:0021879;GO:0021882;GO:0021892;GO:0021893;GO:0030154;GO:0043565;GO:0045597;GO:0045746;GO:0045944;GO:0046533;GO:0048701;GO:0048706;GO:0048715;GO:0048755;GO:0051216;GO:1902871","-","KOG0850-Transcription factor DLX and related proteins with LIM Zn-binding and HOX domains[K]"]
["CRP",0.939685,81.954269,6.446498072,0,0,"up","CRP","C-reactive protein","GO:0005576;GO:0046872","-","-"]
["MORN3",0.411073,35.740383,6.442016668,{"v":1.27e-255,"d":"1.27E-255"},{"v":1.7e-254,"d":"1.70E-254"},"up","MORN3","-","-","-","KOG0231-Junctional membrane complex protein Junctophilin and related MORN repeat proteins[R]"]
["CFAP100",0.408042,35.255619,6.432991743,0,0,"up","CFAP100","-","-","-","-"]
["HYDIN",0.122085,10.343066,6.404634143,0,0,"up","HYDIN","HYDIN, axonemal central pair apparatus protein","GO:0002064;GO:0003341;GO:0007275;GO:0007420;GO:0021591;GO:0060438;GO:1904158;GO:1990718","-","-"]
["TNNC1",5.379739,455.44931,6.403610504,0,0,"up","TNNC1","troponin C1, slow skeletal and cardiac type","GO:0003009;GO:0005509;GO:0005861;GO:0006937;GO:0014883;GO:0031013;GO:0031014;GO:0032972;GO:0042803;GO:0043462;GO:0046872;GO:0048306;GO:0051015;GO:0055010;GO:0060048;GO:1990584","K05865-ko04020 Calcium signaling pathway;ko04260 Cardiac muscle contraction;ko04261 Adrenergic signaling in cardiomyocytes;ko05410 Hypertrophic cardiomyopathy (HCM);ko05414 Dilated cardiomyopathy (DCM)","KOG0027-Calmodulin and related proteins (EF-Hand superfamily)[T]"]
["CCDC78",0.465694,39.28339,6.398393329,0,0,"up","CCDC78","-","-","-","-"]
["CKMT2",1.600231,132.187988,6.368167095,0,0,"up","CKMT2","creatine kinase, mitochondrial 2","GO:0000166;GO:0003824;GO:0004111;GO:0005524;GO:0005739;GO:0005743;GO:0016020;GO:0016301;GO:0016310;GO:0016740;GO:0016772","K00933-ko00330 Arginine and proline metabolism","KOG3581-Creatine kinases[C]"]
["ATXN1L",0.183583,15.007576,6.353114694,0,0,"up","ATXN1L","-","GO:0000122;GO:0003723;GO:0005634;GO:0005654;GO:0005730;GO:0007420;GO:0007612;GO:0007613;GO:0030198;GO:0035176;GO:0048286;GO:1902035","-","KOG4053-Ataxin-1, involved in Ca2+ homeostasis[S]"]
["LOC101751743",0.069361,5.575069,6.328721152,{"v":3.71e-283,"d":"3.71E-283"},{"v":5.33e-282,"d":"5.33E-282"},"up","LOC101751743","-","-","-","-"]
["DNAH9",0.30163,24.238403,6.328370911,0,0,"up","DNAH9","-","GO:0003341;GO:0003777;GO:0005524;GO:0005930;GO:0007018;GO:0008569;GO:0016887;GO:0030286;GO:0031514;GO:0045503;GO:0045505;GO:0051959;GO:0097729;GO:0120135","-","-"]
["INCENP",6.653059,534.601379,6.328301921,0,0,"up","INCENP","inner centromere protein","GO:0000070;GO:0000281;GO:0000775;GO:0000776;GO:0000777;GO:0005515;GO:0005634;GO:0005694;GO:0005721;GO:0005737;GO:0005819;GO:0005856;GO:0005874;GO:0007049;GO:0007059;GO:0030496;GO:0032991;GO:0051301;GO:1902412","-","KOG4456-Inner centromere protein (INCENP), C-terminal domain[D]"]
["TTC25",0.769654,61.807976,6.327439188,0,0,"up","TTC25","-","GO:0005737","-","-"]
["EN1",0.079564,6.347253,6.317872731,{"v":1.62e-79,"d":"1.62E-79"},{"v":9.39e-79,"d":"9.39E-79"},"up","EN1","-","GO:0003677;GO:0005634;GO:0006355;GO:0007275;GO:0043565;GO:0000122;GO:0000978;GO:0003677;GO:0005634;GO:0006355;GO:0007275;GO:0008344;GO:0009953;GO:0009954;GO:0010468;GO:0021549;GO:0030182;GO:0030326;GO:0030901;GO:0030902;GO:0030917;GO:0035115;GO:0035176;GO:0035264;GO:0042756;GO:0043473;GO:0043524;GO:0043565;GO:0045944;GO:0048666;GO:0060173;GO:0061743;GO:1901215;GO:1990403","-","KOG0493-Transcription factor Engrailed, contains HOX domain[R]"]
["LOC770705",2.137332,168.009735,6.296589995,0,0,"up","LOC770705","-","-","-","-"]
["CERKL",0.105709,7.836649,6.212066764,{"v":2.45e-134,"d":"2.45E-134"},{"v":2.02e-133,"d":"2.02E-133"},"up","CERKL","-","GO:0001750;GO:0001917;GO:0003951;GO:0005634;GO:0005737;GO:0005829;GO:0008152;GO:0016301;GO:0016310;GO:0030148;GO:0046625;GO:0048471","-","-"]
["TMEM200C",0.642085,47.035976,6.194856535,0,0,"up","TMEM200C","-","GO:0016020;GO:0016021","-","-"]
["STOML3",0.432565,31.597502,6.19074976,0,0,"up","STOML3","-","GO:0005929;GO:0007165;GO:0016020;GO:0016021;GO:0045121","-","KOG2621-Prohibitins and stomatins of the PID superfamily[C]"]
["PPP4R4",0.448884,32.218189,6.165388918,0,0,"up","PPP4R4","-","GO:0005737;GO:0005829;GO:0008287;GO:0019888;GO:0032515;GO:0080163","-","KOG0211-Protein phosphatase 2A regulatory subunit A and related proteins[T]"]
["UNC45B",0.284616,20.226265,6.151069358,0,0,"up","UNC45B","-","GO:0005829;GO:0051879;GO:0061077","-","KOG4151-Myosin assembly protein/sexual cycle protein and related proteins[ODR]"]
["MDH1B",0.106991,7.599751,6.150390802,{"v":1.51e-98,"d":"1.51E-98"},{"v":1.01e-97,"d":"1.01E-97"},"up","MDH1B","-","GO:0003824;GO:0005737;GO:0005975;GO:0006099;GO:0006107;GO:0006108;GO:0006734;GO:0016615;GO:0016616;GO:0030060;GO:0055114","-","KOG1496-Malate dehydrogenase[C]"]
["MYL2",7.450701,520.99115,6.127738888,0,0,"up","MYL2","myosin, light chain 2, regulatory, cardiac, slow","GO:0003007;GO:0003785;GO:0005509;GO:0005856;GO:0007507;GO:0009791;GO:0015629;GO:0030016;GO:0030308;GO:0042694;GO:0048747;GO:0055003;GO:0055010;GO:0060047;GO:0060048;GO:0097512;GO:0098735","K10351-ko04810 Regulation of actin cytoskeleton;ko04510 Focal adhesion;ko04530 Tight junction;ko04670 Leukocyte transendothelial migration;ko04260 Cardiac muscle contraction;ko04261 Adrenergic signaling in cardiomyocytes;ko05410 Hypertrophic cardiomyopathy (HCM);ko05414 Dilated cardiomyopathy (DCM)","KOG0031-Myosin regulatory light chain, EF-Hand protein superfamily[Z]"]
["RAPSN",0.175511,11.967793,6.091451864,{"v":3.32e-107,"d":"3.32E-107"},{"v":2.32e-106,"d":"2.32E-106"},"up","RAPSN","receptor associated protein of the synapse","GO:0005737;GO:0005794;GO:0005813;GO:0005829;GO:0005856;GO:0005886;GO:0007268;GO:0007271;GO:0016020;GO:0030054;GO:0031594;GO:0033130;GO:0043495;GO:0043525;GO:0045202;GO:0045211;GO:0046872;GO:0099634","-","KOG1941-Acetylcholine receptor-associated protein of the synapse (rapsyn)[W]"]
["LOC100857686",0.586409,38.622787,6.041401216,{"v":1.19e-251,"d":"1.19E-251"},{"v":1.58e-250,"d":"1.58E-250"},"up","LOC100857686","-","-","-","-"]
["LYZ",21.94733,1437.037842,6.032908804,0,0,"up","LYZ","lysozyme (renal amyloidosis)","GO:0003796;GO:0003824;GO:0005515;GO:0005576;GO:0005615;GO:0005737;GO:0005783;GO:0008152;GO:0016231;GO:0016787;GO:0016798;GO:0016998;GO:0019835;GO:0031640;GO:0042742;GO:0042802;GO:0050829;GO:0050830;GO:0051672","-","-"]
["SPHKAP",0.109268,7.116477,6.025220351,{"v":1.61e-288,"d":"1.61E-288"},{"v":2.35e-287,"d":"2.35E-287"},"up","SPHKAP","SPHK1 interactor, AKAP domain containing","GO:0005739;GO:0010738;GO:0051018","-","-"]
["TRIM63",10.375625,665.610474,6.003407988,0,0,"up","TRIM63","-","GO:0005622;GO:0005737;GO:0008270;GO:0031432;GO:0046872","-","KOG4367-Predicted Zn-finger protein[S]"]
["C1QTNF3",1.305507,82.626617,5.983924502,0,0,"up","C1QTNF3","-","GO:0005576;GO:0005581","-","-"]
["ANKEF1",0.1854,11.593337,5.966510834,{"v":4.15e-188,"d":"4.15E-188"},{"v":4.34e-187,"d":"4.34E-187"},"up","ANKEF1","-","-","-","KOG4177-Ankyrin[M]"]
["CLDN9",0.253096,15.55453,5.941506286,{"v":3.31e-92,"d":"3.31E-92"},{"v":2.11e-91,"d":"2.11E-91"},"up","CLDN9","-","GO:0005198;GO:0005886;GO:0005923;GO:0016020;GO:0016021;GO:0030054","-","-"]
["MYOT",4.476834,271.036713,5.919865649,0,0,"up","MYOT","-","GO:0030018","-","KOG4221-Receptor mediating netrin-dependent axon guidance[T]"]
["COLCA2",0.220707,13.356485,5.919264189,{"v":1.51e-92,"d":"1.51E-92"},{"v":9.66e-92,"d":"9.66E-92"},"up","COLCA2","-","-","-","-"]
["CCDC57",0.303075,18.334908,5.918774365,{"v":1.01e-273,"d":"1.01E-273"},{"v":1.41e-272,"d":"1.41E-272"},"up","CCDC57","-","-","-","-"]
["BEST3",0.184268,11.123416,5.915650543,{"v":4.31e-128,"d":"4.31E-128"},{"v":3.42e-127,"d":"3.42E-127"},"up","BEST3","bestrophin 3","GO:0005254;GO:0005886;GO:0006811;GO:0006821;GO:0015698;GO:0016020;GO:0016021;GO:0034707;GO:0043271;GO:1902476","-","KOG3547-Bestrophin (Best vitelliform macular dystrophy-associated protein)[R]"]
["IQCH",0.237715,14.277286,5.908345009,{"v":1.23e-290,"d":"1.23E-290"},{"v":1.81e-289,"d":"1.81E-289"},"up","IQCH","-","-","-","-"]
["CCDC40",0.253992,15.213863,5.904459652,{"v":1.56e-257,"d":"1.56E-257"},{"v":2.09e-256,"d":"2.09E-256"},"up","CCDC40","-","GO:0001947;GO:0003341;GO:0003351;GO:0003356;GO:0005737;GO:0005929;GO:0005930;GO:0030317;GO:0030324;GO:0031514;GO:0035082;GO:0035469;GO:0036159;GO:0044458;GO:0060287;GO:0061512;GO:0070286;GO:0071907;GO:0071910","-","-"]
["LOC107056180",0.447256,26.751137,5.902355565,{"v":2.51e-88,"d":"2.51E-88"},{"v":1.56e-87,"d":"1.56E-87"},"up","LOC107056180","-","-","-","-"]
["CHRNA1",0.233327,13.678891,5.873454198,{"v":1.79e-203,"d":"1.79E-203"},{"v":2.01e-202,"d":"2.01E-202"},"up","CHRNA1","cholinergic receptor nicotinic alpha 1 subunit","GO:0003009;GO:0004888;GO:0005216;GO:0005230;GO:0005886;GO:0005892;GO:0006811;GO:0007271;GO:0007274;GO:0007528;GO:0009986;GO:0015464;GO:0016020;GO:0016021;GO:0019228;GO:0022848;GO:0030054;GO:0031594;GO:0034220;GO:0035094;GO:0042166;GO:0042391;GO:0045202;GO:0045211;GO:0046716;GO:0048630;GO:0050881;GO:0050905;GO:0060078;GO:0060079;GO:0070050;GO:0098655;GO:0099060","K04803-ko04080 Neuroactive ligand-receptor interaction","KOG3645-Acetylcholine receptor[T]"]
["ITIH6",0.872286,50.857677,5.865520521,0,0,"up","ITIH6","-","GO:0004867;GO:0010951;GO:0030212","-","-"]
["RSPH3",0.259669,14.805302,5.833296317,{"v":5.23e-131,"d":"5.23E-131"},{"v":4.23e-130,"d":"4.23E-130"},"up","RSPH3","-","-","-","-"]
["LPO",13.173172,729.205139,5.790650046,0,0,"up","LPO","-","GO:0004601;GO:0006979;GO:0018969;GO:0020037;GO:0036393;GO:0042742;GO:0055114;GO:0098869","K10789-ko04145 Phagosome;ko05202 Transcriptional misregulation in cancers","-"]
["SPEF2",0.254045,14.047172,5.789051834,0,0,"up","SPEF2","-","-","-","KOG3078-Adenylate kinase[F]"]
["UCP3",4.639117,254.272614,5.776382045,0,0,"up","UCP3","uncoupling protein 3","-","-","KOG0753-Mitochondrial fatty acid anion carrier protein/Uncoupling protein[C]"]
["TMEM68L",1.903318,102.950096,5.757284743,0,0,"up","TMEM68L","-","GO:0008152;GO:0016020;GO:0016021;GO:0016746;GO:0016747","-","-"]
["C5H11orf16",0.260273,14.035005,5.752860109,{"v":2.69e-279,"d":"2.69E-279"},{"v":3.84e-278,"d":"3.84E-278"},"up","C5H11orf16","-","-","-","-"]
["ATP6V0A4",0.291716,15.374899,5.719868606,{"v":1.39e-276,"d":"1.39E-276"},{"v":1.97e-275,"d":"1.97E-275"},"up","ATP6V0A4","ATPase, H  transporting, lysosomal V0 subunit a4","GO:0000220;GO:0001503;GO:0005768;GO:0005886;GO:0005903;GO:0006811;GO:0006885;GO:0007588;GO:0007605;GO:0015078;GO:0015991;GO:0016020;GO:0016021;GO:0016324;GO:0016471;GO:0031526;GO:0033179;GO:0045177;GO:0051117;GO:1902600","K02154-ko00190 Oxidative phosphorylation;ko04145 Phagosome;ko04142 Lysosome;ko04966 Collecting duct acid secretion;ko04721 Synaptic vesicle cycle;ko05323 Rheumatoid arthritis;ko05110 Vibrio cholerae infection;ko05120 Epithelial cell signaling in Helicobacter pylori infection;ko05152 Tuberculosis","KOG2189-Vacuolar H+-ATPase V0 sector, subunit a[C]"]
["CCDC65",0.203273,10.669727,5.713960853,{"v":3.54e-116,"d":"3.54E-116"},{"v":2.64e-115,"d":"2.64E-115"},"up","CCDC65","-","GO:0003352;GO:0060271","-","-"]
["MORN2",0.11743,6.156945,5.712341753,{"v":2.69e-27,"d":"2.69E-27"},{"v":8.96e-27,"d":"8.96E-27"},"up","MORN2","MORN repeat containing 2","-","-","KOG0231-Junctional membrane complex protein Junctophilin and related MORN repeat proteins[R]"]
["ATP12A",1.169877,61.187817,5.70881567,0,0,"up","ATP12A","ATPase H /K  transporting non-gastric alpha2 subunit","GO:0000166;GO:0005391;GO:0005524;GO:0006811;GO:0006813;GO:0006814;GO:0010248;GO:0016020;GO:0016021;GO:0016787;GO:0019829;GO:0046872;GO:0099132","K01544-ko00190 Oxidative phosphorylation","KOG0203-Na+/K+ ATPase, alpha subunit[P]"]
["PIH1D3",0.972684,50.527157,5.69894401,0,0,"up","PIH1D3","-","GO:0003341;GO:0030317;GO:0070286","-","-"]
["LBX2",1.084868,55.123089,5.667065316,0,0,"up","LBX2","ladybird homeobox 2","-","-","KOG0488-Transcription factor BarH and related HOX domain proteins[R]"]
["LOC101748060",0.314989,15.8892,5.656601231,0,0,"up","LOC101748060","-","-","-","-"]
["MYOZ2",6.877868,344.352234,5.645779798,0,0,"up","MYOZ2","myozenin 2","GO:0003779;GO:0015629;GO:0030018;GO:0030239;GO:0031433;GO:0051373","-","-"]
["NOV",0.951094,46.657761,5.616385332,0,0,"up","NOV","nephroblastoma overexpressed","GO:0001558;GO:0005178;GO:0005520;GO:0005576;GO:0007155;GO:0007165;GO:0007267;GO:0008083;GO:0008201;GO:0010469;GO:0060548;GO:0001525;GO:0001558;GO:0002062;GO:0005112;GO:0005178;GO:0005520;GO:0005576;GO:0005737;GO:0005921;GO:0010761;GO:0010832;GO:0014909;GO:0030308;GO:0033627;GO:0035767;GO:0043231;GO:0044342;GO:0045747;GO:0046676;GO:0048659;GO:0050728;GO:0060326;GO:0060392;GO:0061484;GO:0071603;GO:0090027;GO:1901223;GO:1902731;GO:1990523","-","-"]
["LOC771972",0.78457,38.083694,5.601127441,{"v":1.46e-236,"d":"1.46E-236"},{"v":1.83e-235,"d":"1.83E-235"},"up","LOC771972","-","-","-","-"]
["CCDC166",0.182897,8.806087,5.589397781,{"v":8.86e-138,"d":"8.86E-138"},{"v":7.41e-137,"d":"7.41E-137"},"up","CCDC166","-","-","-","-"]
["LOC112531968",0.536463,25.699053,5.582092716,{"v":2.55e-132,"d":"2.55E-132"},{"v":2.08e-131,"d":"2.08E-131"},"up","LOC112531968","-","-","-","-"]
["MYOD1",6.898115,327.277954,5.568170433,0,0,"up","MYOD1","myogenic differentiation 1","GO:0000978;GO:0001228;GO:0003677;GO:0005634;GO:0005667;GO:0006351;GO:0006355;GO:0006366;GO:0007275;GO:0007517;GO:0030154;GO:0031490;GO:0035914;GO:0042693;GO:0043966;GO:0043967;GO:0045663;GO:0045944;GO:0046982;GO:0046983;GO:0048743;GO:0070888;GO:0071392;GO:1901741;GO:1905382;GO:1990841;GO:0000381;GO:0000790;GO:0000977;GO:0000978;GO:0001228;GO:0003677;GO:0003682;GO:0003700;GO:0003713;GO:0005634;GO:0005654;GO:0005667;GO:0005737;GO:0005829;GO:0006355;GO:0006357;GO:0006366;GO:0007517;GO:0007518;GO:0007519;GO:0007520;GO:0008134;GO:0009267;GO:0010468;GO:0014902;GO:0014904;GO:0014908;GO:0016604;GO:0019899;GO:0030016;GO:0031490;GO:0031625;GO:0035257;GO:0035914;GO:0043415;GO:0043484;GO:0043503;GO:0043565;GO:0043966;GO:0043967;GO:0045445;GO:0045893;GO:0045944;GO:0046982;GO:0046983;GO:0048741;GO:0051146;GO:0051149;GO:0070888;GO:0071356;GO:0071385;GO:0071392;GO:0071453;GO:1901741;GO:1905382;GO:1990841;GO:2000818","-","KOG3960-Myogenic helix-loop-helix transcription factor[K]"]
["C1H22orf23",0.80055,36.789307,5.522151178,{"v":2.2e-216,"d":"2.20E-216"},{"v":2.59e-215,"d":"2.59E-215"},"up","C1H22orf23","-","-","-","-"]
["C1H11ORF70",0.792671,36.314732,5.517688927,{"v":1.37e-220,"d":"1.37E-220"},{"v":1.63e-219,"d":"1.63E-219"},"up","C1H11ORF70","chromosome 1 open reading frame, human C11orf70","-","-","-"]
["FGG",0.166456,7.615905,5.515802703,{"v":2.92e-69,"d":"2.92E-69"},{"v":1.57e-68,"d":"1.57E-68"},"up","FGG","fibrinogen gamma chain","GO:0005102;GO:0005198;GO:0005577;GO:0005615;GO:0007160;GO:0007596;GO:0009306;GO:0009897;GO:0009986;GO:0030168;GO:0031091;GO:0031639;GO:0034116;GO:0034622;GO:0042730;GO:0045907;GO:0045921;GO:0050714;GO:0050839;GO:0051258;GO:0051592;GO:0070374;GO:0070527;GO:0072378;GO:0090277;GO:1902042;GO:2000352","-","KOG2579-Ficolin and related extracellular proteins[R]"]
["LOC107054848",0.417091,18.390392,5.46244624,{"v":2.03e-139,"d":"2.03E-139"},{"v":1.71e-138,"d":"1.71E-138"},"up","LOC107054848","-","-","-","-"]
["LOC772158",4.373998,190.040909,5.441213642,0,0,"up","LOC772158","-","-","-","-"]
["CDHR3",1.166871,49.996536,5.421111159,0,0,"up","CDHR3","-","GO:0005509;GO:0005886;GO:0007155;GO:0007156;GO:0016020;GO:0016021","-","-"]
["SFTPA1",198.367538,8444.571289,5.411776323,0,0,"up","SFTPA1","surfactant protein A1","-","-","-"]
["PACRG",1.007064,42.306236,5.392643058,0,0,"up","PACRG","-","GO:0001664;GO:0003779;GO:0005829;GO:0005929;GO:0007286;GO:0030544;GO:0031072;GO:0031625;GO:0031982;GO:0043005;GO:0043014;GO:0044297;GO:0048487;GO:0051087;GO:0051879;GO:0060548;GO:0097225","-","KOG3961-Uncharacterized conserved protein[S]"]
["CEP126",0.132447,5.413851,5.353168111,{"v":6.63e-143,"d":"6.63E-143"},{"v":5.69e-142,"d":"5.69E-142"},"up","CEP126","-","GO:0005813;GO:0007052;GO:0031122;GO:0097546;GO:1905515","-","-"]
["TEKT1",1.200481,48.179909,5.326747193,0,0,"up","TEKT1","-","GO:0005634;GO:0015630;GO:0030317;GO:0036126;GO:0060271;GO:0060294","-","KOG2685-Cystoskeletal protein Tektin[Z]"]
["LOC112530139",0.249853,9.97184,5.318708289,0,0,"up","LOC112530139","-","-","-","-"]
["FAM179A",0.333069,13.269938,5.316196737,{"v":1.8e-290,"d":"1.80E-290"},{"v":2.65e-289,"d":"2.65E-289"},"up","FAM179A","family with sequence similarity 179 member A","-","-","-"]
["LRRC2",1.251966,49.090851,5.293186888,0,0,"up","LRRC2","-","-","-","KOG0617-Ras suppressor protein (contains leucine-rich repeats)[T]"]
["ERICH3",2.134876,82.98365,5.280602934,0,0,"up","ERICH3","-","-","-","-"]
["LOC428967",0.382988,14.823813,5.274473587,{"v":6.13e-146,"d":"6.13E-146"},{"v":5.35e-145,"d":"5.35E-145"},"up","LOC428967","-","GO:0004888;GO:0005216;GO:0005230;GO:0005886;GO:0006811;GO:0016020;GO:0016021;GO:0034220","K05189-ko04080 Neuroactive ligand-receptor interaction;ko04727 GABAergic synapse;ko04723 Retrograde endocannabinoid signaling;ko05032 Morphine addiction;ko05033 Nicotine addiction","-"]
["ATP10B",0.131029,5.046401,5.267296794,{"v":2.69e-200,"d":"2.69E-200"},{"v":2.96e-199,"d":"2.96E-199"},"up","ATP10B","-","GO:0000166;GO:0000287;GO:0004012;GO:0005524;GO:0005783;GO:0005886;GO:0015914;GO:0016020;GO:0016021;GO:0016787;GO:0045332","-","KOG0206-P-type ATPase[R]"]
["BMP8A",0.824415,31.159601,5.240162195,0,0,"up","BMP8A","-","GO:0005576;GO:0008083;GO:0010469","K16622-ko04350 TGF-beta signaling pathway;ko04390 Hippo signaling pathway","-"]
["ASCL3",0.878503,32.580414,5.212813913,{"v":7.75e-164,"d":"7.75E-164"},{"v":7.35e-163,"d":"7.35E-163"},"up","ASCL3","-","GO:0000122;GO:0000977;GO:0001227;GO:0003677;GO:0005634;GO:0005667;GO:0006357;GO:0046983","-","KOG4029-Transcription factor HAND2/Transcription factor TAL1/TAL2/LYL1[K]"]
["PFN4",0.268087,9.846131,5.198783767,{"v":1.95e-51,"d":"1.95E-51"},{"v":8.92e-51,"d":"8.92E-51"},"up","PFN4","-","GO:0003779;GO:0003785;GO:0005938;GO:0015629;GO:0042989","K05759-ko04015 Rap1 signaling pathway;ko04013 MAPK signaling pathway - fly;ko04810 Regulation of actin cytoskeleton;ko05132 Salmonella infection;ko05131 Shigellosis","KOG1755-Profilin[Z]"]
["CASC1",0.265249,9.727204,5.196605957,{"v":9.37e-122,"d":"9.37E-122"},{"v":7.2e-121,"d":"7.20E-121"},"up","CASC1","-","-","-","-"]
["VGLL2",0.291346,10.587605,5.183498963,{"v":4.58e-131,"d":"4.58E-131"},{"v":3.71e-130,"d":"3.71E-130"},"up","VGLL2","vestigial like family member 2","GO:0003713;GO:0005634;GO:0005737;GO:0006355;GO:0007519;GO:0008022;GO:0045944","-","-"]
["CCNO",0.363336,13.096648,5.171749483,{"v":3.95e-95,"d":"3.95E-95"},{"v":2.56e-94,"d":"2.56E-94"},"up","CCNO","-","GO:0000278;GO:0005634;GO:0005737;GO:0060271;GO:1903251","-","KOG0653-Cyclin B and related kinase-activating proteins[D]"]
["HAPLN1",2.698679,96.278419,5.156887164,0,0,"up","HAPLN1","hyaluronan and proteoglycan link protein 1","GO:0001501;GO:0005201;GO:0005540;GO:0005576;GO:0007155;GO:0007417","-","-"]
["YF5",0.410943,14.635395,5.154379575,{"v":1.64e-158,"d":"1.64E-158"},{"v":1.52e-157,"d":"1.52E-157"},"up","YF5","MHC class I antigen YF5","GO:0016020;GO:0016021","K06751-ko04514 Cell adhesion molecules (CAMs);ko04144 Endocytosis;ko04145 Phagosome;ko04650 Natural killer cell mediated cytotoxicity;ko04612 Antigen processing and presentation;ko05203 Viral carcinogenesis;ko05320 Autoimmune thyroid disease;ko05330 Allograft rejection;ko05332 Graft-versus-host disease;ko05416 Viral myocarditis;ko04940 Type I diabetes mellitus;ko05166 HTLV-I infection;ko05168 Herpes simplex infection;ko05169 Epstein-Barr virus infection","-"]
["TRIM55",1.259921,44.634113,5.146741575,0,0,"up","TRIM55","tripartite motif containing 55","GO:0005622;GO:0008270;GO:0042802;GO:0046872","-","KOG4367-Predicted Zn-finger protein[S]"]
["QRICH2",0.338244,11.575239,5.096833829,{"v":8.8e-290,"d":"8.80E-290"},{"v":1.29e-288,"d":"1.29E-288"},"up","QRICH2","-","-","-","-"]
["MYBPH",7.428143,252.202301,5.085436039,0,0,"up","MYBPH","myosin binding protein H","GO:0005623;GO:0005859;GO:0006941;GO:0007015;GO:0007155;GO:0008307;GO:0030018;GO:0031430;GO:0031672;GO:0032982;GO:0045214;GO:0051015;GO:0051371;GO:0071688;GO:0097493","-","KOG3513-Neural cell adhesion molecule L1[T]"]
["PLN",6.829531,231.826782,5.085116926,0,0,"up","PLN","phospholamban","GO:0002026;GO:0005246;GO:0005739;GO:0005783;GO:0005789;GO:0006816;GO:0006874;GO:0007219;GO:0008016;GO:0010459;GO:0010880;GO:0010881;GO:0016020;GO:0016021;GO:0016529;GO:0031966;GO:0032780;GO:0033017;GO:0042030;GO:0043086;GO:0045822;GO:0048738;GO:0051924;GO:0051926;GO:0060314;GO:0086004;GO:0086023;GO:0086092;GO:0090279;GO:0090534;GO:1901020;GO:1901077;GO:1901877;GO:1901894;GO:1901895","K05852-ko04020 Calcium signaling pathway;ko04024 cAMP signaling pathway;ko04022 cGMP - PKG signaling pathway;ko04919 Thyroid hormone signaling pathway;ko04261 Adrenergic signaling in cardiomyocytes;ko05414 Dilated cardiomyopathy (DCM)","-"]
["DNAJB13",0.767069,25.970119,5.081352456,{"v":6.1e-168,"d":"6.10E-168"},{"v":5.9e-167,"d":"5.90E-167"},"up","DNAJB13","-","GO:0005737;GO:0005930;GO:0006457;GO:0031514;GO:0036126;GO:0051082;GO:0097224;GO:1904158","-","KOG0714-Molecular chaperone (DnaJ superfamily)[O]"]
["LOC107052966",0.299254,10.113178,5.078722085,{"v":3.34e-50,"d":"3.34E-50"},{"v":1.51e-49,"d":"1.51E-49"},"up","LOC107052966","-","-","-","-"]
["MYPN",0.394997,13.317847,5.075375365,0,0,"up","MYPN","-","GO:0008092;GO:0017124;GO:0030018;GO:0030334;GO:0031674;GO:0045214;GO:0048739;GO:0051015;GO:0051371;GO:0051493","-","[KOG3513-Neural cell adhesion molecule L1[T], KOG4222-Axon guidance receptor Dscam[T]]"]
["LOC112529956",0.563021,18.944925,5.072478884,{"v":3.07e-188,"d":"3.07E-188"},{"v":3.21e-187,"d":"3.21E-187"},"up","LOC112529956","-","-","-","-"]
["SYNPO2L",3.034698,101.310738,5.061090331,0,0,"up","SYNPO2L","-","GO:0005634;GO:0005654;GO:0005829;GO:0016607;GO:0030054","-","KOG3550-Receptor targeting protein Lin-7[W]"]
["PCYT1B",0.324068,10.802061,5.058866221,{"v":2.15e-114,"d":"2.15E-114"},{"v":1.58e-113,"d":"1.58E-113"},"up","PCYT1B","-","-","K00968-ko00564 Glycerophospholipid metabolism;ko00440 Phosphonate and phosphinate metabolism;ko05231 Choline metabolism in cancer","KOG2804-Phosphorylcholine transferase/cholinephosphate cytidylyltransferase[I]"]
["GRPEL2",0.644096,21.408895,5.054790792,0,0,"up","GRPEL2","-","-","-","KOG3003-Molecular chaperone of the GrpE family[O]"]
["CHRNG",5.767409,191.277542,5.05160035,0,0,"up","CHRNG","cholinergic receptor nicotinic gamma subunit","GO:0004888;GO:0005216;GO:0005230;GO:0005886;GO:0005892;GO:0006811;GO:0007271;GO:0007274;GO:0016020;GO:0016021;GO:0022848;GO:0030054;GO:0034220;GO:0035094;GO:0042166;GO:0045202;GO:0045211;GO:0060078;GO:0060079;GO:0098655","K04818-ko04080 Neuroactive ligand-receptor interaction","KOG3645-Acetylcholine receptor[T]"]
["SMKR1",0.347176,11.411218,5.03864176,{"v":8.49e-49,"d":"8.49E-49"},{"v":3.78e-48,"d":"3.78E-48"},"up","SMKR1","-","-","-","-"]
["AANAT",0.232544,7.599687,5.030364379,{"v":4.22e-77,"d":"4.22E-77"},{"v":2.4e-76,"d":"2.40E-76"},"up","AANAT","aralkylamine N-acetyltransferase","GO:0004059;GO:0004060;GO:0005737;GO:0005829;GO:0006474;GO:0007623;GO:0016740;GO:0016746;GO:0030187;GO:0048471;GO:0048511;GO:0071320;GO:0071492","K00669-ko00380 Tryptophan metabolism","KOG4144-Arylalkylamine N-acetyltransferase[R]"]
["ZC2HC1C",1.033303,33.516464,5.019534683,0,0,"up","ZC2HC1C","-","-","-","KOG3940-Uncharacterized conserved protein[S]"]
["UNC93A",0.172272,5.58775,5.019507336,{"v":2.2e-62,"d":"2.20E-62"},{"v":1.11e-61,"d":"1.11E-61"},"up","UNC93A","-","GO:0005886;GO:0016020;GO:0016021","-","KOG3097-Predicted membrane protein[S]"]
["T",0.22309,7.097659,4.991645512,{"v":2.32e-123,"d":"2.32E-123"},{"v":1.8e-122,"d":"1.80E-122"},"up","T","T, brachyury homolog (mouse)","GO:0000122;GO:0000785;GO:0000790;GO:0000978;GO:0000980;GO:0000981;GO:0001085;GO:0001102;GO:0001191;GO:0001570;GO:0001756;GO:0001839;GO:0001843;GO:0003007;GO:0003257;GO:0003677;GO:0003700;GO:0005634;GO:0005737;GO:0006351;GO:0006355;GO:0006357;GO:0007275;GO:0007341;GO:0007498;GO:0007509;GO:0008284;GO:0009653;GO:0009952;GO:0014028;GO:0022414;GO:0023019;GO:0030509;GO:0030903;GO:0036342;GO:0043565;GO:0045944;GO:0048706;GO:0051087;GO:0060070;GO:0060349;GO:0060395;GO:0061371","-","-"]
["CHADL",2.439119,77.022354,4.980845165,0,0,"up","CHADL","chondroadherin-like","GO:0005518;GO:0031012;GO:0032331;GO:0098633;GO:1904027","-","KOG4237-Extracellular matrix protein slit, contains leucine-rich and EGF-like repeats[WT]"]
["VWA3B",0.188996,5.931082,4.971867712,{"v":1.35e-145,"d":"1.35E-145"},{"v":1.17e-144,"d":"1.17E-144"},"up","VWA3B","-","-","-","-"]
["DNAI1",0.595746,18.692369,4.971608252,{"v":8.98e-237,"d":"8.98E-237"},{"v":1.13e-235,"d":"1.13E-235"},"up","DNAI1","-","GO:0003341;GO:0003351;GO:0005737;GO:0005813;GO:0007368;GO:0007507;GO:0008286;GO:0008574;GO:0036157;GO:0036158;GO:0045503;GO:0045504","-","KOG1587-Cytoplasmic dynein intermediate chain[Z]"]
["SMTNL1",2.559573,79.654602,4.959782657,0,0,"up","SMTNL1","-","-","-","-"]
["GAS2L2",0.977386,30.339636,4.956131527,0,0,"up","GAS2L2","-","GO:0008017","-","-"]
["LOC112531314",0.223359,6.872571,4.943413613,{"v":1.16e-34,"d":"1.16E-34"},{"v":4.35e-34,"d":"4.35E-34"},"up","LOC112531314","-","-","-","-"]
["CHRND",7.586124,233.261612,4.942442138,0,0,"up","CHRND","cholinergic receptor nicotinic delta subunit","GO:0004888;GO:0005216;GO:0005230;GO:0005654;GO:0005829;GO:0005886;GO:0005892;GO:0006811;GO:0007271;GO:0007274;GO:0016020;GO:0016021;GO:0022848;GO:0030054;GO:0031594;GO:0034220;GO:0035094;GO:0042166;GO:0042391;GO:0045202;GO:0045211;GO:0048630;GO:0050881;GO:0060078;GO:0060079;GO:0098655;GO:0099060","K04816-ko04080 Neuroactive ligand-receptor interaction","KOG3645-Acetylcholine receptor[T]"]
["CFAP43",1.024428,31.406607,4.938177595,0,0,"up","CFAP43","-","-","-","-"]
["TCTEX1D4",0.698636,20.845692,4.89906447,{"v":9.81e-103,"d":"9.81E-103"},{"v":6.67e-102,"d":"6.67E-102"},"up","TCTEX1D4","-","GO:0001669;GO:0005634;GO:0005737;GO:0005815;GO:0005930;GO:0008157;GO:0036126","-","-"]
["FAM64A",0.648519,19.259693,4.892292054,{"v":2.74e-206,"d":"2.74E-206"},{"v":3.11e-205,"d":"3.11E-205"},"up","FAM64A","-","-","-","-"]
["SAMD15",0.450275,13.268602,4.881066185,{"v":5.79e-66,"d":"5.79E-66"},{"v":3.01e-65,"d":"3.01E-65"},"up","SAMD15","-","-","-","-"]
["CFAP54",0.189099,5.496143,4.861205902,0,0,"up","CFAP54","-","-","-","-"]
["TCAP",49.565731,1428.942139,4.849460682,0,0,"up","TCAP","-","-","-","-"]
["MYO7L2",3.516908,101.089684,4.845184375,0,0,"up","MYO7L2","-","GO:0000166;GO:0003774;GO:0003779;GO:0005524;GO:0016459","-","-"]
["LOC107052453",1.717472,49.348442,4.844646053,{"v":2.17e-296,"d":"2.17E-296"},{"v":3.26e-295,"d":"3.26E-295"},"up","LOC107052453","-","-","-","-"]
["LOC423731",0.57037,16.363087,4.842403036,{"v":1.7e-128,"d":"1.70E-128"},{"v":1.35e-127,"d":"1.35E-127"},"up","LOC423731","-","-","-","-"]
["DNER",0.85188,24.146282,4.825007033,0,0,"up","DNER","-","GO:0005112;GO:0005509;GO:0005769;GO:0005886;GO:0007220;GO:0007417;GO:0010001;GO:0016020;GO:0016021;GO:0030425;GO:0035678;GO:0043025;GO:0045177;GO:0048741;GO:0060088","-","KOG1217-Fibrillins and related proteins containing Ca2+-binding EGF-like domains[T]"]
["MYOM2",6.403675,181.14595,4.822108651,0,0,"up","MYOM2","myomesin 2","GO:0005859;GO:0006936;GO:0006941;GO:0007015;GO:0008307;GO:0019900;GO:0030018;GO:0031430;GO:0045214;GO:0051015;GO:0051371;GO:0071688;GO:0097493","-","KOG4222-Axon guidance receptor Dscam[T]"]
["DPEP2",0.345518,9.655367,4.804498321,{"v":1.04e-160,"d":"1.04E-160"},{"v":9.75e-160,"d":"9.75E-160"},"up","DPEP2","-","GO:0006508;GO:0008233;GO:0008235;GO:0008237;GO:0008239;GO:0016020;GO:0016787;GO:0016805;GO:0031225;GO:0046872","-","KOG4127-Renal dipeptidase[O]"]
["LOC100859304",13.208312,366.229309,4.793229244,0,0,"up","LOC100859304","-","-","-","-"]
["LOC107051636",12.416612,337.776031,4.765723478,0,0,"up","LOC107051636","-","-","-","-"]
["TRAF5",0.23095,6.251029,4.758441244,{"v":1.73e-172,"d":"1.73E-172"},{"v":1.7e-171,"d":"1.70E-171"},"up","TRAF5","TNF receptor associated factor 5","-","K09849-ko04064 NF-kappa B signaling pathway;ko04668 TNF signaling pathway;ko05200 Pathways in cancer;ko05203 Viral carcinogenesis;ko05222 Small cell lung cancer;ko05168 Herpes simplex infection;ko05169 Epstein-Barr virus infection","KOG0297-TNF receptor-associated factor[T]"]
["MYF6",0.921416,24.740484,4.746877264,{"v":1.09e-240,"d":"1.09E-240"},{"v":1.39e-239,"d":"1.39E-239"},"up","MYF6","myogenic factor 6","GO:0001228;GO:0001756;GO:0003677;GO:0005634;GO:0006355;GO:0006366;GO:0007517;GO:0007519;GO:0035914;GO:0045892;GO:0045893;GO:0045944;GO:0046983;GO:0060415;GO:0000978;GO:0001228;GO:0003677;GO:0005634;GO:0006355;GO:0006366;GO:0007275;GO:0007517;GO:0030154;GO:0035914;GO:0042693;GO:0045663;GO:0045944;GO:0046982;GO:0046983;GO:0048743;GO:0070888;GO:0090575;GO:1901741","-","KOG3960-Myogenic helix-loop-helix transcription factor[K]"]
["SPOCK3",0.558392,14.722467,4.720597357,{"v":1.55e-218,"d":"1.55E-218"},{"v":1.83e-217,"d":"1.83E-217"},"up","SPOCK3","-","GO:0005509;GO:0005539;GO:0019800","-","KOG3555-Ca2+-binding proteoglycan Testican[R]"]
["ZMYND10",1.127686,29.480181,4.708308067,{"v":1.41e-276,"d":"1.41E-276"},{"v":1.99e-275,"d":"1.99E-275"},"up","ZMYND10","-","-","-","-"]
["FNDC5",3.385331,88.19709,4.703362251,0,0,"up","FNDC5","fibronectin type III domain containing 5","GO:0005576;GO:0005783;GO:0005886;GO:0014850;GO:0016020;GO:0016021;GO:0090336","-","-"]
["MYH1D",10.371752,266.808319,4.68507213,0,0,"up","MYH1D","myosin, heavy chain 1D, skeletal muscle","GO:0000166;GO:0003774;GO:0003779;GO:0005524;GO:0016459;GO:0051015","K10352-ko04530 Tight junction","KOG0161-Myosin class II heavy chain[Z]"]
["C9H2ORF82",4.155174,106.598869,4.681139429,{"v":6.8e-227,"d":"6.80E-227"},{"v":8.28e-226,"d":"8.28E-226"},"up","C9H2ORF82","chromosome 9 open reading frame, human C2orf82","GO:0016020;GO:0016021;GO:0031012;GO:0051216;GO:0071944","-","-"]
["DNAH12",0.301521,7.667218,4.66837281,0,0,"up","DNAH12","-","GO:0003341;GO:0003777;GO:0005524;GO:0007018;GO:0008569;GO:0016887;GO:0030286;GO:0036156;GO:0036159;GO:0045503;GO:0045505;GO:0051959","-","-"]
["MNS1",0.586413,14.893806,4.666651574,{"v":1.98e-213,"d":"1.98E-213"},{"v":2.29e-212,"d":"2.29E-212"},"up","MNS1","-","GO:0005635;GO:0005882;GO:0005930;GO:0007283;GO:0031514;GO:0036126;GO:0042802;GO:0044782;GO:0045724;GO:0070986","-","-"]
["C1orf228",0.384682,9.550048,4.633769754,{"v":2.84e-72,"d":"2.84E-72"},{"v":1.56e-71,"d":"1.56E-71"},"up","C1orf228","-","-","-","-"]
["ASB14",0.352353,8.692995,4.624759912,{"v":2.18e-126,"d":"2.18E-126"},{"v":1.71e-125,"d":"1.71E-125"},"up","ASB14","-","-","-","KOG4177-Ankyrin[M]"]
["SPACA9",0.452604,11.050649,4.609737956,{"v":3.27e-93,"d":"3.27E-93"},{"v":2.1e-92,"d":"2.10E-92"},"up","SPACA9","sperm acrosome associated 9","GO:0001669;GO:0005737;GO:0005881;GO:0048306","-","-"]
["LOC107054726",0.757438,18.438669,4.605462906,{"v":9.53e-87,"d":"9.53E-87"},{"v":5.84e-86,"d":"5.84E-86"},"up","LOC107054726","-","-","-","-"]
["LOC112531814",3.297161,80.104538,4.602587735,0,0,"up","LOC112531814","-","-","-","-"]
["IMPG2",0.739639,17.907717,4.597616316,0,0,"up","IMPG2","interphotoreceptor matrix proteoglycan 2","GO:0005201;GO:0005540;GO:0007601;GO:0008201;GO:0016020;GO:0016021;GO:0033165;GO:0043235","-","-"]
["ARMC3",0.553129,13.235106,4.580609956,{"v":7.41e-181,"d":"7.41E-181"},{"v":7.54e-180,"d":"7.54E-180"},"up","ARMC3","-","GO:0005634;GO:0005737;GO:0006886;GO:0015031;GO:0016020;GO:0016192;GO:0030117","-","KOG4224-Armadillo repeat protein VAC8 required for vacuole fusion, inheritance and cytosol-to-vacuole protein targeting[U]"]
["LOC112532140",12.920475,309.038818,4.58005705,0,0,"up","LOC112532140","-","-","-","-"]
["CAPN3",1.418685,33.910587,4.579109559,0,0,"up","CAPN3","calpain 3","GO:0003824;GO:0004198;GO:0005509;GO:0005622;GO:0005634;GO:0005737;GO:0005829;GO:0005886;GO:0006508;GO:0008233;GO:0008234;GO:0008307;GO:0012501;GO:0014718;GO:0014850;GO:0016787;GO:0030016;GO:0030018;GO:0030163;GO:0030239;GO:0030315;GO:0031402;GO:0031432;GO:0031648;GO:0032947;GO:0032991;GO:0033234;GO:0043066;GO:0043122;GO:0045214;GO:0045661;GO:0045862;GO:0045892;GO:0045893;GO:0046872;GO:0050790;GO:0051092;GO:0051281;GO:0051592;GO:0055103;GO:0061061;GO:0065003;GO:0070315;GO:0071277;GO:0071472;GO:0072657;GO:0097264;GO:2001015","-","KOG0045-Cytosolic Ca2+-dependent cysteine protease (calpain), large subunit (EF-Hand protein superfamily)[OT]"]
["CCDC170",0.970647,23.096872,4.572606952,0,0,"up","CCDC170","-","-","-","-"]
["CDHR4",1.800555,42.794197,4.570901603,0,0,"up","CDHR4","-","-","-","KOG4289-Cadherin EGF LAG seven-pass G-type receptor[T]"]
["EFHC2",0.274216,6.430958,4.55164901,{"v":1.55e-87,"d":"1.55E-87"},{"v":9.57e-87,"d":"9.57E-87"},"up","EFHC2","EF-hand domain containing 2","GO:0005615;GO:0005623;GO:1990830","-","KOG0043-Uncharacterized conserved protein, contains DM10 domain[S]"]
["MURC",6.476479,151.581253,4.548737836,0,0,"up","MURC","-","GO:0005737;GO:0005886;GO:0005901;GO:0010468;GO:0030018;GO:0035023;GO:0045944","-","-"]
["MAATS1",0.268112,6.230812,4.53851249,{"v":5.48e-128,"d":"5.48E-128"},{"v":4.35e-127,"d":"4.35E-127"},"up","MAATS1","-","-","-","-"]
["MYLK4",0.942147,21.792894,4.531761806,0,0,"up","MYLK4","-","-","K00907-ko04020 Calcium signaling pathway;ko04022 cGMP - PKG signaling pathway;ko04810 Regulation of actin cytoskeleton;ko04510 Focal adhesion;ko04611 Platelet activation;ko04921 Oxytocin signaling pathway;ko04270 Vascular smooth muscle contraction;ko04971 Gastric acid secretion","KOG0032-Ca2+/calmodulin-dependent protein kinase, EF-Hand protein superfamily[T]"]
["FBXO15",0.29489,6.770892,4.521097102,{"v":3.11e-66,"d":"3.11E-66"},{"v":1.63e-65,"d":"1.63E-65"},"up","FBXO15","-","GO:0000151;GO:0043161","-","KOG2120-SCF ubiquitin ligase, Skp2 component[O]"]
["CNGB1",0.269509,6.187493,4.520949632,{"v":1.42e-158,"d":"1.42E-158"},{"v":1.31e-157,"d":"1.31E-157"},"up","CNGB1","-","-","K04952-ko04024 cAMP signaling pathway;ko04022 cGMP - PKG signaling pathway;ko04744 Phototransduction;ko04740 Olfactory transduction","-"]
["IQCD",0.526905,12.04058,4.514218209,{"v":1.17e-140,"d":"1.17E-140"},{"v":9.94e-140,"d":"9.94E-140"},"up","IQCD","-","-","-","-"]
["TF",30.971251,706.804932,4.512310544,0,0,"up","TF","transferrin (ovotransferrin)","GO:0005576;GO:0005615;GO:0005623;GO:0006811;GO:0046872;GO:0055072","K14736-ko04066 HIF-1 signaling pathway;ko04978 Mineral absorption","-"]
["LOC771515",0.250449,5.672278,4.501339485,{"v":2.74e-227,"d":"2.74E-227"},{"v":3.34e-226,"d":"3.34E-226"},"up","LOC771515","-","-","-","-"]
["WNT7B",0.240961,5.416574,4.490509063,{"v":8.72e-39,"d":"8.72E-39"},{"v":3.46e-38,"d":"3.46E-38"},"up","WNT7B","Wnt family member 7B","GO:0005102;GO:0005109;GO:0005576;GO:0005615;GO:0007275;GO:0010469;GO:0016055;GO:0021871;GO:0030182;GO:0045165;GO:0048018;GO:0048144;GO:0060070;GO:0070307;GO:0071300;GO:0072089","K00572-ko04310 Wnt signaling pathway;ko04390 Hippo signaling pathway;ko04150 mTOR signaling pathway;ko04550 Signaling pathways regulating pluripotency of stem cells;ko04916 Melanogenesis;ko05200 Pathways in cancer;ko05205 Proteoglycans in cancer;ko05217 Basal cell carcinoma;ko05224 Breast cancer;ko05166 HTLV-I infection","KOG3913-Wnt family of developmental regulators[T]"]
["TMEM182",6.095468,136.952164,4.489791259,0,0,"up","TMEM182","-","GO:0016020;GO:0016021","-","-"]
["ARX",1.753416,39.033577,4.476475453,0,0,"up","ARX","-","GO:0000122;GO:0000980;GO:0000981;GO:0001764;GO:0003677;GO:0003682;GO:0005634;GO:0006355;GO:0007275;GO:0007411;GO:0010628;GO:0021759;GO:0021772;GO:0021800;GO:0021831;GO:0021846;GO:0021853;GO:0030900;GO:0042127;GO:0043565;GO:0044241;GO:0046622;GO:0072148","-","KOG0484-Transcription factor PHOX2/ARIX, contains HOX domain[K]"]
["CCDC181",0.631605,13.905836,4.460524078,{"v":1.71e-171,"d":"1.71E-171"},{"v":1.67e-170,"d":"1.67E-170"},"up","CCDC181","-","GO:0002177;GO:0008017;GO:0036126","-","-"]
["MIR1456",0.256369,5.641161,4.459698385,0.00432376,0.006296432,"up","MIR1456","microRNA 1456","-","-","-"]
["LOC112530976",8.435616,184.834229,4.453594717,0,0,"up","LOC112530976","-","-","-","-"]
["MYOM1",4.135127,89.598145,4.43746532,0,0,"up","MYOM1","myomesin 1","GO:0006936;GO:0010628;GO:0010737;GO:0019900;GO:0030017;GO:0031430;GO:0042802;GO:0042803;GO:0050714","-","KOG4221-Receptor mediating netrin-dependent axon guidance[T]"]
["LOC107050476",7.790267,167.58371,4.427065333,0,0,"up","LOC107050476","-","-","-","-"]
["CFAP69",0.713137,15.219754,4.415621972,0,0,"up","CFAP69","-","-","-","-"]
["ZNF385B",2.764089,58.836052,4.411824468,0,0,"up","ZNF385B","-","GO:0002039;GO:0003676;GO:0003723;GO:0005634;GO:0008270;GO:0046872;GO:0072332","-","-"]
["NOS2",10.78204,228.755051,4.407101527,0,0,"up","NOS2","nitric oxide synthase 2","GO:0001666;GO:0003958;GO:0004517;GO:0005102;GO:0005516;GO:0005622;GO:0005737;GO:0005777;GO:0005829;GO:0006527;GO:0006801;GO:0006809;GO:0006954;GO:0007263;GO:0007623;GO:0009617;GO:0010181;GO:0010629;GO:0016491;GO:0018119;GO:0020037;GO:0030863;GO:0031284;GO:0032310;GO:0032496;GO:0034617;GO:0034618;GO:0035690;GO:0042127;GO:0042177;GO:0042742;GO:0042803;GO:0045776;GO:0046872;GO:0048471;GO:0050660;GO:0050661;GO:0050796;GO:0051712;GO:0055114;GO:0071222;GO:0071346;GO:0072604;GO:0072606;GO:0097755;GO:1900015","K13241-ko00220 Arginine biosynthesis;ko00330 Arginine and proline metabolism;ko04066 HIF-1 signaling pathway;ko04020 Calcium signaling pathway;ko04146 Peroxisome;ko05200 Pathways in cancer;ko05222 Small cell lung cancer;ko05132 Salmonella infection;ko05133 Pertussis;ko05152 Tuberculosis;ko05146 Amoebiasis;ko05145 Toxoplasmosis;ko05140 Leishmaniasis;ko05142 Chagas disease (American trypanosomiasis)","KOG1158-NADP/FAD dependent oxidoreductase[C]"]
["RPL3L",0.372427,7.879262,4.403030935,{"v":3.68e-55,"d":"3.68E-55"},{"v":1.75e-54,"d":"1.75E-54"},"up","RPL3L","ribosomal protein L3 like","GO:0000027;GO:0003723;GO:0003735;GO:0005622;GO:0005840;GO:0006412;GO:0022625","K02925-ko03010 Ribosome","KOG0746-60S ribosomal protein L3 and related proteins[J]"]
["MORN5",3.512476,72.906105,4.375479355,{"v":1.95e-306,"d":"1.95E-306"},{"v":3.02e-305,"d":"3.02E-305"},"up","MORN5","-","-","-","-"]
["LOC112532686",3.764492,78.041794,4.373719844,0,0,"up","LOC112532686","-","-","-","-"]
["LOC100859106",6.113235,126.611984,4.372334127,0,0,"up","LOC100859106","-","-","-","-"]
["MHCIY",1.076493,22.166515,4.363971125,{"v":2.96e-246,"d":"2.96E-246"},{"v":3.84e-245,"d":"3.84E-245"},"up","MHCIY","MHC-like class I Y","GO:0016020;GO:0016021","-","-"]
["TMEM182L",2.507315,51.620747,4.363735857,0,0,"up","TMEM182L","-","GO:0016020;GO:0016021","-","-"]
["TTC24",0.808521,16.573895,4.357483631,{"v":2.11e-158,"d":"2.11E-158"},{"v":1.95e-157,"d":"1.95E-157"},"up","TTC24","-","-","-","-"]
["LOC107052288",9.785009,200.557663,4.357300102,0,0,"up","LOC107052288","-","-","-","-"]
["ITGB1BP2",1.670735,34.093479,4.350940997,{"v":2.28e-151,"d":"2.28E-151"},{"v":2.03e-150,"d":"2.03E-150"},"up","ITGB1BP2","-","GO:0005509;GO:0008270;GO:0030018","-","KOG1667-Zn2+-binding protein Melusin/RAR1, contains CHORD domain[R]"]
["IP6K3",2.624826,53.228138,4.341895405,0,0,"up","IP6K3","-","GO:0000828;GO:0000831;GO:0005634;GO:0005737;GO:0006468;GO:0016301;GO:0016310;GO:0016740;GO:0032958;GO:0046488","K07756-ko04070 Phosphatidylinositol signaling system","KOG1620-Inositol polyphosphate multikinase, component of the ARGR transcription regulatory complex[KIT]"]
["LDB3",15.579842,315.893707,4.341686689,0,0,"up","LDB3","LIM domain binding 3","-","-","KOG1703-Adaptor protein Enigma and related PDZ-LIM proteins[TZ]"]
["TSNAXIP1",0.453994,9.103494,4.325675234,{"v":9.54e-120,"d":"9.54E-120"},{"v":7.22e-119,"d":"7.22E-119"},"up","TSNAXIP1","-","GO:0005737","-","-"]
["NOG",0.360025,7.080025,4.297585459,{"v":3.61e-26,"d":"3.61E-26"},{"v":1.18e-25,"d":"1.18E-25"},"up","NOG","noggin","GO:0000122;GO:0001501;GO:0001649;GO:0001655;GO:0001657;GO:0001706;GO:0001707;GO:0001837;GO:0001839;GO:0001843;GO:0003149;GO:0003151;GO:0003203;GO:0003223;GO:0005576;GO:0005615;GO:0005623;GO:0007275;GO:0007389;GO:0007411;GO:0007417;GO:0007420;GO:0007492;GO:0008045;GO:0009953;GO:0010628;GO:0010629;GO:0019955;GO:0021510;GO:0021533;GO:0021915;GO:0021983;GO:0030154;GO:0030336;GO:0030509;GO:0030510;GO:0030514;GO:0035019;GO:0042060;GO:0042474;GO:0042733;GO:0042803;GO:0045596;GO:0045668;GO:0045944;GO:0048318;GO:0048570;GO:0048646;GO:0048706;GO:0048712;GO:0048762;GO:0050679;GO:0051151;GO:0051216;GO:0055009;GO:0060044;GO:0060173;GO:0060272;GO:0060302;GO:0060325;GO:0060394;GO:0060412;GO:0060425;GO:0060513;GO:0060676;GO:0060825;GO:0061037;GO:0061053;GO:0061312;GO:0061384;GO:0061626;GO:0071773;GO:0090090;GO:0090190;GO:0090193;GO:1902747;GO:1905006;GO:2000313;GO:2001234","K04658-ko04350 TGF-beta signaling pathway","-"]
["LOC107054725",0.465981,9.108243,4.288829745,{"v":1.36e-86,"d":"1.36E-86"},{"v":8.34e-86,"d":"8.34E-86"},"up","LOC107054725","-","-","-","-"]
["SVOPL",0.401137,7.791379,4.279711746,{"v":3.22e-232,"d":"3.22E-232"},{"v":4e-231,"d":"4.00E-231"},"up","SVOPL","-","GO:0016020;GO:0016021;GO:0055085","-","KOG0253-Synaptic vesicle transporter SV2 (major facilitator superfamily)[R]"]
["CBLN1",0.660867,12.648556,4.258468924,{"v":1.83e-110,"d":"1.83E-110"},{"v":1.32e-109,"d":"1.32E-109"},"up","CBLN1","-","GO:0007157;GO:0009306;GO:0021707;GO:0042803;GO:0043083;GO:0045202;GO:0051965;GO:0090394;GO:0098688;GO:0098978;GO:0099151;GO:1900454;GO:1905606","-","-"]
["IQCG",0.460191,8.78749,4.255146468,{"v":3.26e-63,"d":"3.26E-63"},{"v":1.66e-62,"d":"1.66E-62"},"up","IQCG","-","GO:0002177;GO:0005516;GO:0005737;GO:0007286;GO:0007288;GO:0030544;GO:0031514;GO:0036126","-","-"]
["COCH",4.073382,77.625664,4.252234683,0,0,"up","COCH","cochlin","GO:0005518;GO:0005576;GO:0007605;GO:0031012;GO:0042742;GO:0045089;GO:0062023;GO:0005576;GO:0007605;GO:0031012;GO:0042742;GO:0045089;GO:0062023","-","-"]
["ACTC1",3.136813,59.686493,4.250033057,0,0,"up","ACTC1","actin, alpha, cardiac muscle 1","GO:0000166;GO:0005524;GO:0005737;GO:0005856;GO:0005884;GO:0016887;GO:0017022;GO:0030017;GO:0030048;GO:0030240;GO:0031032;GO:0031674;GO:0033275;GO:0042643;GO:0043066;GO:0045202;GO:0055003;GO:0055008;GO:0060047;GO:0070252;GO:0098978;GO:0000166;GO:0005524","K12314-ko04260 Cardiac muscle contraction;ko04261 Adrenergic signaling in cardiomyocytes;ko05410 Hypertrophic cardiomyopathy (HCM);ko05414 Dilated cardiomyopathy (DCM)","KOG0676-Actin and related proteins[Z]"]
["C4H2orf81",0.802795,15.156531,4.238764148,{"v":1.78e-112,"d":"1.78E-112"},{"v":1.3e-111,"d":"1.30E-111"},"up","C4H2orf81","-","-","-","-"]
["B3GNT4",0.266088,5.021029,4.238007703,{"v":1.09e-58,"d":"1.09E-58"},{"v":5.36e-58,"d":"5.36E-58"},"up","B3GNT4","-","-","K07971-ko00601 Glycosphingolipid biosynthesis - lacto and neolacto series","KOG2287-Galactosyltransferases[G]"]
["IQUB",0.865439,16.109615,4.21834607,0,0,"up","IQUB","-","GO:0001669;GO:0007224;GO:0031514;GO:0060271","-","-"]
["KLHL40",2.169057,40.177643,4.211253061,0,0,"up","KLHL40","-","GO:0004842;GO:0016567;GO:0031397;GO:0031463;GO:0031672;GO:0031674;GO:0032435;GO:0048741","-","KOG4441-Proteins containing BTB/POZ and Kelch domains, involved in regulatory/signal transduction processes[TR]"]
["KLHL41",11.048715,203.920624,4.206057199,0,0,"up","KLHL41","-","GO:0005634;GO:0005737;GO:0005789;GO:0005829;GO:0005856;GO:0005886;GO:0016567;GO:0030239;GO:0031430;GO:0031463;GO:0033017;GO:0035914;GO:0045214;GO:0045661;GO:0048741;GO:2000291;GO:2001014","-","KOG4441-Proteins containing BTB/POZ and Kelch domains, involved in regulatory/signal transduction processes[TR]"]
["LOC101751669",0.407711,7.524036,4.205887965,{"v":2.3e-89,"d":"2.30E-89"},{"v":1.44e-88,"d":"1.44E-88"},"up","LOC101751669","-","-","-","-"]
["KCNA3",0.42485,7.824471,4.202967747,{"v":6.7e-96,"d":"6.70E-96"},{"v":4.38e-95,"d":"4.38E-95"},"up","KCNA3","potassium voltage-gated channel subfamily A member 3","GO:0005216;GO:0005244;GO:0005249;GO:0005267;GO:0006811;GO:0006813;GO:0008076;GO:0016020;GO:0016021;GO:0030424;GO:0034765;GO:0051260;GO:0055085;GO:0071805","-","KOG1545-Voltage-gated shaker-like K+ channel KCNA[P]"]
["ALPK3",4.829715,88.697037,4.198875947,0,0,"up","ALPK3","-","GO:0004674;GO:0005524;GO:0006468","-","-"]
["SLC25A47",0.842414,15.3797,4.190354139,0,0,"up","SLC25A47","-","GO:0005476;GO:0005743;GO:0006839;GO:0015226;GO:0015879;GO:0016020;GO:0016021;GO:0022857;GO:0055085;GO:1902603","-","KOG0762-Mitochondrial carrier protein[C]"]
["DHRS7C",5.172166,94.261452,4.187827421,0,0,"up","DHRS7C","dehydrogenase/reductase (SDR family) member 7C","GO:0004745;GO:0010880;GO:0014801;GO:0016491;GO:0033017;GO:0055114","-","KOG1205-Predicted dehydrogenase[Q]"]
["CACNA1S",9.041817,164.649536,4.186641917,0,0,"up","CACNA1S","calcium channel, voltage-dependent, L type, alpha 1S subunit","GO:0005216;GO:0005244;GO:0005245;GO:0005262;GO:0005516;GO:0005737;GO:0005886;GO:0005891;GO:0006811;GO:0006816;GO:0006936;GO:0008331;GO:0016020;GO:0016021;GO:0030315;GO:0031674;GO:0034765;GO:0042383;GO:0055085;GO:0070588;GO:0071313;GO:1990454","K04857-ko04010 MAPK signaling pathway;ko04020 Calcium signaling pathway;ko04024 cAMP signaling pathway;ko04022 cGMP - PKG signaling pathway;ko04911 Insulin secretion;ko04912 GnRH signaling pathway;ko04921 Oxytocin signaling pathway;ko04924 Renin secretion;ko04925 Aldosterone synthesis and secretion;ko04260 Cardiac muscle contraction;ko04261 Adrenergic signaling in cardiomyocytes;ko04270 Vascular smooth muscle contraction;ko04727 GABAergic synapse;ko04725 Cholinergic synapse;ko04726 Serotonergic synapse;ko04723 Retrograde endocannabinoid signaling;ko05010 Alzheimer's disease;ko05410 Hypertrophic cardiomyopathy (HCM);ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC);ko05414 Dilated cardiomyopathy (DCM)","KOG2301-Voltage-gated Ca2+ channels, alpha1 subunits[PT]"]
["CCDC96",0.359811,6.497818,4.174644137,{"v":4.45e-43,"d":"4.45E-43"},{"v":1.86e-42,"d":"1.86E-42"},"up","CCDC96","-","-","-","-"]
["KLHL30",3.005809,54.243839,4.173634043,0,0,"up","KLHL30","-","GO:0004842;GO:0016567;GO:0031463","-","KOG4441-Proteins containing BTB/POZ and Kelch domains, involved in regulatory/signal transduction processes[TR]"]
["LOC112530475",0.949736,17.101057,4.170415149,{"v":5.85e-108,"d":"5.85E-108"},{"v":4.12e-107,"d":"4.12E-107"},"up","LOC112530475","-","-","-","-"]
["DNALI1",4.165208,74.138817,4.153768648,0,0,"up","DNALI1","-","GO:0005737;GO:0005929;GO:0005930;GO:0030175;GO:0045504;GO:0097729","-","-"]
["TRIM54",5.74893,102.002022,4.149160477,0,0,"up","TRIM54","-","GO:0005622;GO:0005874;GO:0005875;GO:0007026;GO:0008017;GO:0008270;GO:0046872;GO:0055001;GO:0070507","-","KOG4367-Predicted Zn-finger protein[S]"]
["GOLGA7B",0.445971,7.898097,4.146483282,{"v":3.08e-67,"d":"3.08E-67"},{"v":1.63e-66,"d":"1.63E-66"},"up","GOLGA7B","-","-","-","KOG4069-Uncharacterized conserved protein[S]"]
["TRDN",7.692583,135.660294,4.14038661,0,0,"up","TRDN","-","GO:0005102;GO:0005829;GO:0005886;GO:0006936;GO:0009617;GO:0010649;GO:0010880;GO:0014701;GO:0014808;GO:0016020;GO:0016021;GO:0016529;GO:0044325;GO:0060047;GO:0060316;GO:0086036","-","-"]
["CTGF",24.498911,430.404114,4.134902341,0,0,"up","CTGF","connective tissue growth factor","GO:0001502;GO:0001503;GO:0001525;GO:0001558;GO:0001894;GO:0005178;GO:0005520;GO:0005576;GO:0005615;GO:0007155;GO:0007160;GO:0007165;GO:0007229;GO:0007267;GO:0008022;GO:0008201;GO:0008543;GO:0010629;GO:0016477;GO:0030154;GO:0030324;GO:0031012;GO:0032330;GO:0035988;GO:0045597;GO:0046330;GO:0051496;GO:0060548;GO:0061448;GO:0070374;GO:0072593","K06827-ko04390 Hippo signaling pathway","-"]
["CA3B",1.285742,22.279371,4.11503542,{"v":1.07e-226,"d":"1.07E-226"},{"v":1.3e-225,"d":"1.30E-225"},"up","CA3B","carbonic anhydrase 3B","GO:0004089;GO:0008270;GO:0046872","K01672-ko00910 Nitrogen metabolism","KOG0382-Carbonic anhydrase[R]"]
["LOC112533510",51.171246,883.186035,4.109312092,0,0,"up","LOC112533510","-","-","-","-"]
["COL27A1",3.387439,57.982479,4.097350144,0,0,"up","COL27A1","-","GO:0003431;GO:0005201;GO:0005583;GO:0030198","-","-"]
["LOC112531372",2.067375,35.175072,4.088681369,{"v":8.35e-78,"d":"8.35E-78"},{"v":4.78e-77,"d":"4.78E-77"},"up","LOC112531372","-","-","-","-"]
["TULP1",0.791677,13.348167,4.075585893,{"v":2.88e-120,"d":"2.88E-120"},{"v":2.19e-119,"d":"2.19E-119"},"up","TULP1","tubby like protein 1","GO:0001750;GO:0001895;GO:0001917;GO:0005546;GO:0005576;GO:0005829;GO:0005886;GO:0006910;GO:0016192;GO:0016358;GO:0042462;GO:0042995;GO:0043679;GO:0045202;GO:0045494;GO:0050766;GO:0050908;GO:0051015;GO:0060041;GO:1903546","-","KOG2502-Tub family proteins[R]"]
["LOC107049660",35.249126,591.466431,4.068636898,0,0,"up","LOC107049660","-","-","-","-"]
["STYXL1",1.054968,17.664766,4.065603494,{"v":1.62e-120,"d":"1.62E-120"},{"v":1.23e-119,"d":"1.23E-119"},"up","STYXL1","-","GO:0006470;GO:0008138;GO:0016311","-","-"]
["LOC107053416",0.387297,6.438005,4.055101466,0,0,"up","LOC107053416","-","GO:0005576;GO:0016020;GO:0016021","-","-"]
["RPS6KA2",0.312036,5.169774,4.050316824,{"v":3.39e-105,"d":"3.39E-105"},{"v":2.34e-104,"d":"2.34E-104"},"up","RPS6KA2","-","GO:0000166;GO:0000287;GO:0001556;GO:0002035;GO:0004672;GO:0004674;GO:0004711;GO:0005524;GO:0005634;GO:0005737;GO:0005819;GO:0006468;GO:0007507;GO:0010628;GO:0010659;GO:0016301;GO:0016310;GO:0016740;GO:0018105;GO:0035556;GO:0045835;GO:0060047;GO:0070613;GO:0071322","K04373-ko04010 MAPK signaling pathway;ko04150 mTOR signaling pathway;ko04114 Oocyte meiosis;ko04914 Progesterone-mediated oocyte maturation;ko04720 Long-term potentiation;ko04722 Neurotrophin signaling pathway;ko04931 Insulin resistance","KOG0603-Ribosomal protein S6 kinase[T]"]
["ANKRD2",1.090209,17.923368,4.039165121,{"v":3.2e-168,"d":"3.20E-168"},{"v":3.1e-167,"d":"3.10E-167"},"up","ANKRD2","-","GO:0000122;GO:0000791;GO:0001817;GO:0003682;GO:0003712;GO:0005634;GO:0005737;GO:0005829;GO:0006357;GO:0010832;GO:0016605;GO:0030016;GO:0030017;GO:0031432;GO:0031674;GO:0035914;GO:0043231;GO:0043422;GO:0043619;GO:0045445;GO:0045662;GO:0061629;GO:1902253;GO:2000291","-","KOG4177-Ankyrin[M]"]
["PFKM",37.417377,614.147888,4.036805768,0,0,"up","PFKM","phosphofructokinase, muscle","GO:0000166;GO:0003824;GO:0003872;GO:0005524;GO:0005634;GO:0005737;GO:0005829;GO:0005945;GO:0005980;GO:0006002;GO:0006096;GO:0008022;GO:0008152;GO:0008443;GO:0016301;GO:0016310;GO:0016324;GO:0016740;GO:0019900;GO:0032024;GO:0042593;GO:0042802;GO:0042803;GO:0045944;GO:0046716;GO:0046835;GO:0046872;GO:0051259;GO:0061615;GO:0061621;GO:0070061;GO:0093001;GO:0097228","K00850-ko01200 Carbon metabolism;ko01230 Biosynthesis of amino acids;ko00010 Glycolysis / Gluconeogenesis;ko00030 Pentose phosphate pathway;ko00051 Fructose and mannose metabolism;ko00052 Galactose metabolism;ko00680 Methane metabolism;ko03018 RNA degradation;ko04152 AMPK signaling pathway;ko05230 Central carbon metabolism in cancer","KOG2440-Pyrophosphate-dependent phosphofructo-1-kinase[G]"]
["LOC101748860",0.341518,5.561006,4.02531237,{"v":4.4e-83,"d":"4.40E-83"},{"v":2.62e-82,"d":"2.62E-82"},"up","LOC101748860","-","-","-","-"]
["RNF207",6.907939,112.432404,4.024658739,0,0,"up","RNF207","-","-","-","KOG4367-Predicted Zn-finger protein[S]"]
["LOC112530484",2.77412,45.076241,4.022265111,0,0,"up","LOC112530484","-","-","-","-"]
["LOC107050760",25.500658,413.223297,4.018315215,0,0,"up","LOC107050760","-","-","-","-"]
["TMOD4",15.402953,249.16246,4.01580785,0,0,"up","TMOD4","tropomodulin 4","GO:0005523;GO:0005623;GO:0005865;GO:0016020;GO:0051015;GO:0051694","-","KOG3735-Tropomodulin and leiomodulin[Z]"]
["C2orf50",0.814323,13.149055,4.013214158,0,0,"up","C2orf50","-","-","-","-"]
["MYOZ3",3.756702,60.127052,4.000475642,0,0,"up","MYOZ3","-","-","-","-"]
["VWC2L",0.327034,5.231032,3.999583057,{"v":1.67e-119,"d":"1.67E-119"},{"v":1.26e-118,"d":"1.26E-118"},"up","VWC2L","-","GO:0005615;GO:0030514;GO:0032281;GO:0045666","-","-"]
["PI3",0.567579,9.026753,3.991314014,{"v":7.02e-23,"d":"7.02E-23"},{"v":2.16e-22,"d":"2.16E-22"},"up","PI3","-","-","-","-"]
["OBSCN",4.307168,67.299744,3.965789515,0,0,"up","OBSCN","-","GO:0000166;GO:0004672;GO:0005089;GO:0005524;GO:0006468;GO:0016301;GO:0016310;GO:0016740;GO:0035023","-","-"]
["SLC19A3",0.873704,13.617616,3.962185751,0,0,"up","SLC19A3","-","GO:0016020;GO:0016021;GO:0051180;GO:0071934;GO:0090482","-","-"]
["NEBL1",6.205247,96.659912,3.961357138,0,0,"up","NEBL1","-","-","-","-"]
["ABRA",2.483443,38.625042,3.959122962,0,0,"up","ABRA","-","GO:0000060;GO:0003779;GO:0005886;GO:0015629;GO:0030016;GO:0035025;GO:0045893;GO:0045944;GO:0051091","-","KOG3376-Uncharacterized conserved protein[S]"]
["LOC417973",0.342965,5.330348,3.958096464,{"v":5.32e-34,"d":"5.32E-34"},{"v":1.97e-33,"d":"1.97E-33"},"up","LOC417973","-","-","-","-"]
["JAKMIP2",0.341091,5.281927,3.952835769,{"v":2.56e-92,"d":"2.56E-92"},{"v":1.63e-91,"d":"1.63E-91"},"up","JAKMIP2","-","GO:0005794;GO:0008017;GO:0019900","-","-"]
["ATP1B4",19.882536,306.274841,3.945253173,0,0,"up","ATP1B4","ATPase Na /K  transporting family member beta 4","GO:0005634;GO:0005637;GO:0005890;GO:0006355;GO:0006811;GO:0006813;GO:0006814;GO:0016020;GO:0016021","K01540-ko04024 cAMP signaling pathway;ko04022 cGMP - PKG signaling pathway;ko04911 Insulin secretion;ko04918 Thyroid hormone synthesis;ko04919 Thyroid hormone signaling pathway;ko04260 Cardiac muscle contraction;ko04261 Adrenergic signaling in cardiomyocytes;ko04970 Salivary secretion;ko04971 Gastric acid secretion;ko04972 Pancreatic secretion;ko04976 Bile secretion;ko04973 Carbohydrate digestion and absorption;ko04974 Protein digestion and absorption;ko04978 Mineral absorption;ko04960 Aldosterone-regulated sodium reabsorption;ko04961 Endocrine and other factor-regulated calcium reabsorption;ko04964 Proximal tubule bicarbonate reclamation","KOG3927-Na+/K+ ATPase, beta subunit[P]"]
["MIR1562",0.586261,9.017879,3.94317316,0.003329086,0.004893749,"up","MIR1562","microRNA 1562","-","-","-"]
["MAP3K19",0.416058,6.394279,3.94192513,{"v":6.63e-152,"d":"6.63E-152"},{"v":5.93e-151,"d":"5.93E-151"},"up","MAP3K19","-","GO:0004672;GO:0004674;GO:0005524;GO:0005737;GO:0006468;GO:0007346;GO:0023014;GO:0031098;GO:0032147;GO:0042981","-","-"]
["TNNC2",368.410614,5652.113281,3.939403849,0,0,"up","TNNC2","troponin C2, fast skeletal type","GO:0003009;GO:0003779;GO:0005509;GO:0005861;GO:0006937;GO:0046872;GO:0048306;GO:0051015","K12042-ko04020 Calcium signaling pathway","KOG0027-Calmodulin and related proteins (EF-Hand superfamily)[T]"]
["TRDNL",2.348378,35.770596,3.929037605,0,0,"up","TRDNL","-","-","-","-"]
["CFAP74",0.497818,7.582554,3.928993566,{"v":3.84e-211,"d":"3.84E-211"},{"v":4.42e-210,"d":"4.42E-210"},"up","CFAP74","-","-","-","-"]
["TMEM82",0.611976,9.292201,3.924473381,{"v":1.68e-68,"d":"1.68E-68"},{"v":8.97e-68,"d":"8.97E-68"},"up","TMEM82","-","-","-","-"]
["SMPX",16.233494,245.856293,3.920769828,0,0,"up","SMPX","small muscle protein, X-linked","GO:0003674;GO:0005634;GO:0005737;GO:0005927;GO:0006941;GO:0031430;GO:0043034;GO:0043292","-","-"]
["USP2",9.304056,140.906662,3.920736233,0,0,"up","USP2","-","GO:0000122;GO:0004843;GO:0005634;GO:0005737;GO:0005938;GO:0006511;GO:0016579;GO:0030332;GO:0031625;GO:0032922;GO:0036459;GO:0042802;GO:0043153;GO:0045475;GO:0045931;GO:0048471;GO:0048512;GO:0050821;GO:0004843;GO:0005737;GO:0006508;GO:0006511;GO:0008233;GO:0008234;GO:0016579;GO:0016787;GO:0036459;GO:0046872;GO:0048471;GO:0048511","-","KOG1868-Ubiquitin C-terminal hydrolase[O]"]
["MYOZ1",28.466406,431.112823,3.920733211,0,0,"up","MYOZ1","-","GO:0003779;GO:0015629;GO:0030018;GO:0030239;GO:0031433;GO:0051373","-","-"]
["MYLPF",290.65918,4396.635254,3.918999472,0,0,"up","MYLPF","myosin light chain, phosphorylatable, fast skeletal muscle","GO:0005509;GO:0016459;GO:0046872","K12758-ko04810 Regulation of actin cytoskeleton;ko04510 Focal adhesion;ko04530 Tight junction;ko04670 Leukocyte transendothelial migration","-"]
["RFLNA",0.419512,6.343053,3.918393413,0,0,"up","RFLNA","-","GO:0031005;GO:0032432;GO:0048705;GO:0061181;GO:0061182;GO:0061572;GO:1900158","-","-"]
["SH3BGR",3.672809,54.846336,3.900439467,0,0,"up","SH3BGR","-","GO:0005737","-","-"]
["CD24",59.585285,886.370178,3.894881346,0,0,"up","CD24","CD24 molecule","GO:0007155;GO:0016020;GO:0016021","-","-"]
["SIX2",2.814163,41.766514,3.891568937,{"v":7.92e-194,"d":"7.92E-194"},{"v":8.45e-193,"d":"8.45E-193"},"up","SIX2","SIX homeobox 2","GO:0000978;GO:0001656;GO:0001822;GO:0002062;GO:0003337;GO:0003677;GO:0003700;GO:0005634;GO:0006355;GO:0006366;GO:0006606;GO:0007501;GO:0008134;GO:0008283;GO:0009948;GO:0016477;GO:0030278;GO:0032330;GO:0042474;GO:0043565;GO:0044877;GO:0045596;GO:0045944;GO:0048557;GO:0048701;GO:0048704;GO:0072006;GO:0072028;GO:0072038;GO:0072137;GO:0072161;GO:0090189;GO:0097168;GO:1902732","-","-"]
["KIF9",1.893721,28.020811,3.887203011,0,0,"up","KIF9","-","GO:0000166;GO:0002102;GO:0003774;GO:0003777;GO:0005524;GO:0005871;GO:0005874;GO:0007018;GO:0008017;GO:0016887;GO:0022617;GO:0031982;GO:0046983;GO:0071801;GO:1903008","-","KOG4280-Kinesin-like protein[Z]"]
["MELTF",2.101701,31.043945,3.884682561,0,0,"up","MELTF","melanotransferrin","GO:0005506;GO:0005576;GO:0005615;GO:0006811;GO:0009986;GO:0010756;GO:0046658;GO:0046872;GO:0055072;GO:0090091;GO:1900025","-","-"]
["PITX3",6.128736,90.514198,3.884482644,0,0,"up","PITX3","-","GO:0000978;GO:0002088;GO:0002089;GO:0003677;GO:0003700;GO:0005634;GO:0006355;GO:0006366;GO:0007275;GO:0007626;GO:0010468;GO:0030901;GO:0043565;GO:0045893;GO:0045944;GO:0048666;GO:0070306;GO:0071542","-","-"]
["FAM81A",0.653201,9.634835,3.882661055,{"v":2.33e-267,"d":"2.33E-267"},{"v":3.22e-266,"d":"3.22E-266"},"up","FAM81A","-","-","-","-"]
["CCDC173L",2.309375,34.058846,3.882455189,0,0,"up","CCDC173L","-","-","-","-"]
["CASQ2",19.980726,291.242706,3.865541009,0,0,"up","CASQ2","calsequestrin 2","GO:0002027;GO:0005509;GO:0005622;GO:0005737;GO:0010649;GO:0010880;GO:0010881;GO:0014802;GO:0016529;GO:0030018;GO:0030314;GO:0033018;GO:0043267;GO:0045214;GO:0048306;GO:0051208;GO:0051258;GO:0060048;GO:0060306;GO:0060315;GO:0071313;GO:1901017","-","KOG0912-Thiol-disulfide isomerase and thioredoxin[OC]"]
["GRM4",1.067816,15.522148,3.861593239,{"v":5.53e-303,"d":"5.53E-303"},{"v":8.47e-302,"d":"8.47E-302"},"up","GRM4","-","GO:0000187;GO:0004930;GO:0005622;GO:0005886;GO:0005887;GO:0007165;GO:0007186;GO:0007196;GO:0008066;GO:0016020;GO:0016021;GO:0031410;GO:0042734;GO:0043410;GO:0051966","K04607-ko04072 Phospholipase D signaling pathway;ko04080 Neuroactive ligand-receptor interaction;ko04724 Glutamatergic synapse;ko04742 Taste transduction","KOG1056-Glutamate-gated metabotropic ion channel receptor subunit GRM2 and related subunits, G-protein coupled receptor superfamily[PT]"]
["CEP78",0.92322,13.407587,3.860231327,{"v":3.74e-153,"d":"3.74E-153"},{"v":3.36e-152,"d":"3.36E-152"},"up","CEP78","-","GO:0005813;GO:0036064;GO:0044782","-","-"]
["STC2",4.501435,65.10585,3.854330288,0,0,"up","STC2","-","GO:0005179;GO:0005576;GO:0005783;GO:0005794;GO:0006874;GO:0006979;GO:0010469;GO:0010629;GO:0019899;GO:0020037;GO:0030968;GO:0034976;GO:0040015;GO:0042803;GO:0046885;GO:0048471;GO:0055074;GO:2001256","-","-"]
["AVD",2.909143,42.022625,3.852500165,{"v":2.81e-120,"d":"2.81E-120"},{"v":2.14e-119,"d":"2.14E-119"},"up","AVD","avidin","GO:0005576;GO:0009374;GO:0019731","-","-"]
["MYH1G",3.356969,48.454216,3.85139108,0,0,"up","MYH1G","-","GO:0000166;GO:0003774;GO:0003779;GO:0005524;GO:0016459;GO:0051015","K10352-ko04530 Tight junction","-"]
["PDPN",3.817317,54.983032,3.848355564,0,0,"up","PDPN","-","GO:0005102;GO:0005829;GO:0005886;GO:0007266;GO:0010718;GO:0016020;GO:0016021;GO:0016323;GO:0016324;GO:0019956;GO:0030335;GO:0031258;GO:0031410;GO:0031527;GO:0031528;GO:0032587;GO:0042995;GO:0044319;GO:0045121;GO:0051087;GO:0061851;GO:0071437;GO:0090091;GO:0097197;GO:1901731;GO:1905863;GO:2000392","-","-"]
["UBXN11",1.156458,16.593811,3.842860483,{"v":2.13e-277,"d":"2.13E-277"},{"v":3.03e-276,"d":"3.03E-276"},"up","UBXN11","-","-","-","KOG2086-Protein tyrosine phosphatase SHP1/Cofactor for p97 ATPase-mediated vesicle membrane fusion[Y]"]
["MYBPC1",19.890446,283.283936,3.832101263,0,0,"up","MYBPC1","-","GO:0005859;GO:0006936;GO:0006941;GO:0007015;GO:0008307;GO:0030018;GO:0031430;GO:0045214;GO:0051015;GO:0051371;GO:0071688;GO:0097493","-","KOG3513-Neural cell adhesion molecule L1[T]"]
["NPTX2",1.893464,26.885283,3.827716761,0,0,"up","NPTX2","-","GO:0003674;GO:0005575;GO:0008150;GO:0008306;GO:0098962;GO:0098978","-","-"]
["ADAMTS3",2.253585,31.990662,3.827357076,0,0,"up","ADAMTS3","-","GO:0004175;GO:0004222;GO:0005615;GO:0006508;GO:0008233;GO:0008237;GO:0010573;GO:0016485;GO:0032964;GO:1900748","-","KOG3538-Disintegrin metalloproteinases with thrombospondin repeats[O]"]
["LOC112531900",0.525495,7.431607,3.821925268,{"v":1.04e-59,"d":"1.04E-59"},{"v":5.18e-59,"d":"5.18E-59"},"up","LOC112531900","-","-","-","-"]
["CHAD",38.267315,540.311035,3.819605563,0,0,"up","CHAD","-","GO:0004860;GO:0005737;GO:0006469;GO:0019221;GO:0046426;GO:0060348;GO:1900155","K06248-ko04151 PI3K-Akt signaling pathway;ko04512 ECM-receptor interaction;ko04510 Focal adhesion","-"]
["SCN4A",2.397129,33.798157,3.817565125,0,0,"up","SCN4A","sodium voltage-gated channel alpha subunit 4","GO:0001518;GO:0005216;GO:0005244;GO:0005248;GO:0005272;GO:0005886;GO:0006811;GO:0006814;GO:0016020;GO:0016021;GO:0034220;GO:0034765;GO:0035725;GO:0055085","-","KOG2301-Voltage-gated Ca2+ channels, alpha1 subunits[PT]"]
["CLEC19A",1.568174,22.067961,3.814795785,{"v":6.92e-91,"d":"6.92E-91"},{"v":4.36e-90,"d":"4.36E-90"},"up","CLEC19A","-","-","-","-"]
["APOBEC2",50.888332,714.908142,3.812351074,0,0,"up","APOBEC2","-","GO:0003824;GO:0004126;GO:0008270;GO:0009972;GO:0016554;GO:0016556;GO:0016814;GO:0042802;GO:0080111","-","-"]
["LOC112530469",21.20183,297.80127,3.812089207,0,0,"up","LOC112530469","-","-","-","-"]
["NKX2-5",1.51475,21.230036,3.808955207,{"v":3.33e-158,"d":"3.33E-158"},{"v":3.08e-157,"d":"3.08E-157"},"up","NKX2-5","NK2 homeobox 5","GO:0000122;GO:0000978;GO:0001190;GO:0001228;GO:0001570;GO:0001947;GO:0003007;GO:0003148;GO:0003151;GO:0003161;GO:0003162;GO:0003166;GO:0003168;GO:0003208;GO:0003211;GO:0003221;GO:0003222;GO:0003278;GO:0003285;GO:0003342;GO:0003350;GO:0003677;GO:0003682;GO:0003700;GO:0003712;GO:0005634;GO:0005667;GO:0005737;GO:0006355;GO:0006357;GO:0006366;GO:0007507;GO:0007512;GO:0008134;GO:0008284;GO:0010628;GO:0010667;GO:0010735;GO:0010736;GO:0010765;GO:0010832;GO:0030097;GO:0030154;GO:0030509;GO:0030878;GO:0032991;GO:0032993;GO:0035050;GO:0042803;GO:0043066;GO:0043565;GO:0044212;GO:0045214;GO:0045666;GO:0045823;GO:0045893;GO:0045944;GO:0046982;GO:0048536;GO:0048738;GO:0051891;GO:0055005;GO:0055007;GO:0055008;GO:0055117;GO:0060037;GO:0060038;GO:0060043;GO:0060047;GO:0060048;GO:0060070;GO:0060261;GO:0060347;GO:0060412;GO:0060413;GO:0060928;GO:0060929;GO:0060971;GO:0071772;GO:0072358;GO:0090090;GO:0090575;GO:1903779","-","KOG0842-Transcription factor tinman/NKX2-3, contains HOX domain[K]"]
["METTL21EP",0.37681,5.25282,3.80118299,{"v":2.41e-43,"d":"2.41E-43"},{"v":1.01e-42,"d":"1.01E-42"},"up","METTL21EP","-","-","-","-"]
["LRRC39",0.533226,7.423173,3.799216959,{"v":8.39e-168,"d":"8.39E-168"},{"v":8.11e-167,"d":"8.11E-167"},"up","LRRC39","-","-","-","KOG0444-Cytoskeletal regulator Flightless-I (contains leucine-rich and gelsolin repeats)[Z]"]
["LMOD2",6.783511,94.201256,3.795642216,0,0,"up","LMOD2","leiomodin 2","GO:0003779;GO:0003785;GO:0005523;GO:0005737;GO:0005856;GO:0005865;GO:0005884;GO:0006936;GO:0030016;GO:0030017;GO:0030041;GO:0030239;GO:0030838;GO:0031430;GO:0045010;GO:0045214;GO:0051694","-","KOG3735-Tropomodulin and leiomodulin[Z]"]
["NRIP1",0.818956,11.35253,3.793084097,0,0,"up","NRIP1","-","GO:0000118;GO:0000122;GO:0000790;GO:0000978;GO:0001543;GO:0003712;GO:0003713;GO:0003714;GO:0005102;GO:0005634;GO:0005730;GO:0006357;GO:0007623;GO:0016607;GO:0019915;GO:0030331;GO:0030728;GO:0032922;GO:0035257;GO:0035259;GO:0042826;GO:0042974;GO:0045944;GO:0046965;GO:0071392","-","-"]
["ACTN2",15.915325,218.861725,3.781531152,0,0,"up","ACTN2","actinin alpha 2","GO:0003779;GO:0005509;GO:0005515;GO:0005546;GO:0005737;GO:0005886;GO:0005925;GO:0006936;GO:0008092;GO:0019904;GO:0030017;GO:0030018;GO:0030035;GO:0030175;GO:0030274;GO:0030374;GO:0030375;GO:0031432;GO:0042391;GO:0042802;GO:0042803;GO:0043267;GO:0043268;GO:0044325;GO:0045214;GO:0046872;GO:0046983;GO:0048041;GO:0051015;GO:0051289;GO:0051373;GO:0051695;GO:0055013;GO:0070080;GO:0072659;GO:0086097;GO:1901017;GO:1901018;GO:1903508;GO:2000009;GO:2001137;GO:2001259","-","KOG0035-Ca2+-binding actin-bundling protein (actinin), alpha chain (EF-Hand protein superfamily)[Z]"]
["CDH15",3.984372,54.428009,3.771925007,0,0,"up","CDH15","-","GO:0005509;GO:0005794;GO:0005829;GO:0005886;GO:0005901;GO:0007155;GO:0007156;GO:0016020;GO:0016021;GO:0031594","K06809-ko04514 Cell adhesion molecules (CAMs)","[KOG1176-Acyl-CoA synthetase[I], KOG4289-Cadherin EGF LAG seven-pass G-type receptor[T]]"]
["MYF5",1.505414,20.517429,3.768617762,{"v":7.95e-78,"d":"7.95E-78"},{"v":4.55e-77,"d":"4.55E-77"},"up","MYF5","myogenic factor 5","GO:0000978;GO:0001228;GO:0001502;GO:0001503;GO:0001756;GO:0001952;GO:0003677;GO:0005634;GO:0005654;GO:0006351;GO:0006355;GO:0006357;GO:0006366;GO:0007275;GO:0007517;GO:0007519;GO:0030154;GO:0030198;GO:0035914;GO:0042693;GO:0043010;GO:0043565;GO:0045663;GO:0045944;GO:0046982;GO:0046983;GO:0048644;GO:0048704;GO:0048743;GO:0060415;GO:0070888;GO:0090575;GO:1901741","-","KOG3960-Myogenic helix-loop-helix transcription factor[K]"]
["RRAD",1.293966,17.633104,3.768414843,{"v":1.65e-298,"d":"1.65E-298"},{"v":2.5e-297,"d":"2.50E-297"},"up","RRAD","RRAD, Ras related glycolysis inhibitor and calcium channel regulator","GO:0000166;GO:0003924;GO:0005525;GO:0007165;GO:0016020;GO:1901841;GO:1901842","-","KOG0395-Ras-related GTPase[R]"]
["NOG2",1.25902,17.141691,3.76713633,{"v":3.65e-53,"d":"3.65E-53"},{"v":1.69e-52,"d":"1.69E-52"},"up","NOG2","noggin 2","GO:0005576;GO:0007275;GO:0030154;GO:0030514;GO:0045596;GO:0051216","K04658-ko04350 TGF-beta signaling pathway","-"]
["AKR1D1",3.440998,46.723171,3.763239231,{"v":5.77e-292,"d":"5.77E-292"},{"v":8.57e-291,"d":"8.57E-291"},"up","AKR1D1","aldo-keto reductase family 1 member D1","GO:0005829;GO:0006699;GO:0006707;GO:0007586;GO:0008207;GO:0008209;GO:0016491;GO:0047568;GO:0055114","K00251-ko00120 Primary bile acid biosynthesis;ko00140 Steroid hormone biosynthesis","KOG1577-Aldo/keto reductase family proteins[R]"]
["LOC107051134",601.920837,8162.18457,3.761309669,0,0,"up","LOC107051134","-","-","-","-"]
["MIR133A1",3.029209,40.929405,3.756124669,{"v":5.3e-08,"d":"5.30E-08"},{"v":1.06e-07,"d":"1.06E-07"},"up","MIR133A1","microRNA 133a-1","-","-","-"]
["LRRC56",0.418976,5.639798,3.750703981,{"v":1.03e-70,"d":"1.03E-70"},{"v":5.61e-70,"d":"5.61E-70"},"up","LRRC56","-","-","-","-"]
["OCM2",23.021315,308.692291,3.745127306,0,0,"up","OCM2","oncomodulin 2","-","-","KOG0028-Ca2+-binding protein (centrin/caltractin), EF-Hand superfamily protein[ZD]"]
["CARNS1",0.907805,12.093697,3.735729094,{"v":3.5e-222,"d":"3.50E-222"},{"v":4.19e-221,"d":"4.19E-221"},"up","CARNS1","carnosine synthase 1","GO:0000166;GO:0005524;GO:0005575;GO:0016874;GO:0016887;GO:0035499;GO:0046872;GO:0047730;GO:0102102;GO:0016887;GO:0035499;GO:0047730","K14755-ko00330 Arginine and proline metabolism;ko00340 Histidine metabolism;ko00410 beta-Alanine metabolism","-"]
["EFCAB1",1.991293,26.429028,3.730345946,{"v":4.6e-103,"d":"4.60E-103"},{"v":3.13e-102,"d":"3.13E-102"},"up","EFCAB1","-","GO:0005509","-","KOG0044-Ca2+ sensor (EF-Hand superfamily)[T]"]
["STK32C",1.155073,15.274341,3.7250542,{"v":9.21e-287,"d":"9.21E-287"},{"v":1.34e-285,"d":"1.34E-285"},"up","STK32C","-","GO:0000166;GO:0004672;GO:0004674;GO:0005524;GO:0005622;GO:0006468;GO:0018105;GO:0035556","-","KOG0598-Ribosomal protein S6 kinase and related proteins[RT]"]
["DRC3",0.823409,10.86592,3.722057302,{"v":1.97e-95,"d":"1.97E-95"},{"v":1.28e-94,"d":"1.28E-94"},"up","DRC3","-","GO:0005737;GO:0005930","-","KOG1644-U2-associated snRNP A' protein[A]"]
["RYR3",1.354044,17.772461,3.714296944,0,0,"up","RYR3","ryanodine receptor 3","GO:0005216;GO:0005219;GO:0005262;GO:0005509;GO:0005623;GO:0005886;GO:0006811;GO:0006816;GO:0006874;GO:0015278;GO:0016020;GO:0016021;GO:0051209;GO:0055085;GO:0070588","K04963-ko04020 Calcium signaling pathway;ko04921 Oxytocin signaling pathway;ko04970 Salivary secretion;ko04713 Circadian entrainment;ko05010 Alzheimer's disease","KOG2243-Ca2+ release channel (ryanodine receptor)[T]"]
["PPP1R3A",1.698576,22.290874,3.714055508,0,0,"up","PPP1R3A","-","GO:0016020;GO:0016021","K07189-ko04910 Insulin signaling pathway;ko04931 Insulin resistance","KOG3986-Protein phosphatase, regulatory subunit PPP1R3C/D[OT]"]
["CRYAB",13.662345,178.877121,3.71069184,0,0,"up","CRYAB","crystallin alpha B","GO:0001540;GO:0001666;GO:0002088;GO:0005212;GO:0005634;GO:0005737;GO:0005739;GO:0005829;GO:0005886;GO:0007021;GO:0007517;GO:0010629;GO:0010941;GO:0030018;GO:0032387;GO:0032463;GO:0042542;GO:0042802;GO:0042803;GO:0043010;GO:0043066;GO:0043154;GO:0043209;GO:0043292;GO:0044877;GO:0046872;GO:0050821;GO:0051082;GO:0051260;GO:0060561;GO:0071480;GO:1905907","K09542-ko04141 Protein processing in endoplasmic reticulum;ko04213 Longevity regulating pathway - multiple species","KOG3591-Alpha crystallins[O]"]
["ADPRHL1",6.3894,83.437378,3.706941457,0,0,"up","ADPRHL1","-","GO:0005096;GO:0005622;GO:0006886;GO:0012505;GO:0017137;GO:0031338;GO:0090630","-","-"]
["C20H20orf96",1.041287,13.534577,3.700210134,{"v":5.87e-104,"d":"5.87E-104"},{"v":4.03e-103,"d":"4.03E-103"},"up","C20H20orf96","-","-","-","-"]
["MYOC",6.859478,88.91526,3.696260344,0,0,"up","MYOC","-","-","-","KOG3545-Olfactomedin and related extracellular matrix glycoproteins[W]"]
["TMOD1",3.39121,43.38306,3.677259785,0,0,"up","TMOD1","tropomodulin 1","GO:0003779;GO:0005523;GO:0005865;GO:0005884;GO:0006936;GO:0007015;GO:0008180;GO:0008344;GO:0016020;GO:0030016;GO:0030017;GO:0030239;GO:0030863;GO:0042383;GO:0043034;GO:0051015;GO:0051694;GO:0070307","-","KOG3735-Tropomodulin and leiomodulin[Z]"]
["TNNI2",200.483093,2555.81665,3.672231861,0,0,"up","TNNI2","troponin I2, fast skeletal type","GO:0003009;GO:0003779;GO:0005634;GO:0005861;GO:0031014;GO:0045893;GO:0046872;GO:0060048","-","KOG3977-Troponin I[Z]"]
["KCNJ11",0.682422,8.653958,3.664624057,{"v":1.24e-81,"d":"1.24E-81"},{"v":7.3e-81,"d":"7.30E-81"},"up","KCNJ11","-","GO:0005242;GO:0005244;GO:0005249;GO:0005524;GO:0005886;GO:0005887;GO:0006006;GO:0006811;GO:0006813;GO:0008282;GO:0015272;GO:0016020;GO:0016021;GO:0030315;GO:0030506;GO:0033198;GO:0034765;GO:0042391;GO:0042493;GO:0044325;GO:0046676;GO:0050796;GO:0050877;GO:0071805","-","KOG3827-Inward rectifier K+ channel[P]"]
["ATP6V0D2",1.114266,14.111278,3.662683071,{"v":2.7e-113,"d":"2.70E-113"},{"v":1.98e-112,"d":"1.98E-112"},"up","ATP6V0D2","ATPase H  transporting V0 subunit d2","GO:0005765;GO:0005769;GO:0006811;GO:0007034;GO:0007035;GO:0008553;GO:0015078;GO:0015991;GO:0016020;GO:0016324;GO:0016471;GO:0033179;GO:0046961","K02146-ko00190 Oxidative phosphorylation;ko04145 Phagosome;ko04142 Lysosome;ko04966 Collecting duct acid secretion;ko04721 Synaptic vesicle cycle;ko05203 Viral carcinogenesis;ko05323 Rheumatoid arthritis;ko05110 Vibrio cholerae infection;ko05120 Epithelial cell signaling in Helicobacter pylori infection;ko05152 Tuberculosis","KOG2957-Vacuolar H+-ATPase V0 sector, subunit d[C]"]
["SLC29A4",0.512518,6.48443,3.661305184,{"v":2.79e-52,"d":"2.79E-52"},{"v":1.29e-51,"d":"1.29E-51"},"up","SLC29A4","-","GO:0005337;GO:0008504;GO:0015844;GO:0016020;GO:0016021;GO:0055085;GO:1901642","-","KOG1479-Nucleoside transporter[F]"]
["LOC101749021",0.475562,5.989392,3.654704213,{"v":2.12e-46,"d":"2.12E-46"},{"v":9.24e-46,"d":"9.24E-46"},"up","LOC101749021","-","-","-","-"]
["SUSD5",0.649043,8.145496,3.649616584,{"v":1.11e-136,"d":"1.11E-136"},{"v":9.23e-136,"d":"9.23E-136"},"up","SUSD5","-","GO:0005540;GO:0007155;GO:0007219;GO:0016020;GO:0016021","-","-"]
["MAK",0.58759,7.36123,3.6470651,{"v":6.72e-201,"d":"6.72E-201"},{"v":7.45e-200,"d":"7.45E-200"},"up","MAK","-","GO:0000166;GO:0001750;GO:0001917;GO:0003713;GO:0004672;GO:0004674;GO:0005524;GO:0005634;GO:0005737;GO:0005813;GO:0005929;GO:0005930;GO:0006468;GO:0010468;GO:0030496;GO:0031514;GO:0032391;GO:0035556;GO:0042073;GO:0045494;GO:0046777;GO:0060271;GO:0072686;GO:0097542;GO:1902856;GO:1903508","-","-"]
["UNC5C",1.049731,13.117753,3.643429034,0,0,"up","UNC5C","unc-5 netrin receptor C","GO:0005042;GO:0005886;GO:0007165;GO:0007275;GO:0007411;GO:0007420;GO:0016020;GO:0016021;GO:0030054;GO:0030334;GO:0033564;GO:0038007;GO:0043005;GO:0043065;GO:0045202","-","KOG1480-Netrin transmembrane receptor unc-5[T]"]
["C9orf116",6.814132,84.878174,3.63879182,{"v":1.18e-296,"d":"1.18E-296"},{"v":1.79e-295,"d":"1.79E-295"},"up","C9orf116","-","-","-","-"]
["TNC",2.88551,35.742188,3.630729717,0,0,"up","TNC","tenascin C","GO:0005576;GO:0005604;GO:0005614;GO:0007155;GO:0007528;GO:0008284;GO:0009611;GO:0010628;GO:0014012;GO:0042127;GO:0045545;GO:0060739;GO:0060740;GO:0062023;GO:0098966","K06252-ko04151 PI3K-Akt signaling pathway;ko04512 ECM-receptor interaction;ko04510 Focal adhesion;ko05206 MicroRNAs in cancer","KOG2579-Ficolin and related extracellular proteins[R]"]
["PFKFB4",8.684662,106.717613,3.619184791,0,0,"up","PFKFB4","6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4","GO:0003824;GO:0003873;GO:0004331;GO:0005524;GO:0006000;GO:0006003;GO:0008152;GO:0016311;GO:0042802;GO:0043540;GO:0046835","K19028-ko00051 Fructose and mannose metabolism;ko04152 AMPK signaling pathway;ko04922 Glucagon signaling pathway","KOG0234-Fructose-6-phosphate 2-kinase/fructose-2,6-biphosphatase[G]"]
["UGP2",109.487495,1343.960327,3.617652543,0,0,"up","UGP2","UDP-glucose pyrophosphorylase 2","GO:0003983;GO:0005737;GO:0005977;GO:0006011;GO:0008152;GO:0016740;GO:0016779;GO:0042802;GO:0070569","K00963-ko00040 Pentose and glucuronate interconversions;ko00052 Galactose metabolism;ko00500 Starch and sucrose metabolism;ko00520 Amino sugar and nucleotide sugar metabolism","KOG2638-UDP-glucose pyrophosphorylase[G]"]
["SPATA18",3.872193,47.473301,3.615893602,0,0,"up","SPATA18","-","GO:0005737;GO:0005741;GO:0006974;GO:0033554;GO:0035694;GO:0035695;GO:0043231;GO:0005737;GO:0005739;GO:0005741;GO:0006974;GO:0016020;GO:0033554;GO:0035694;GO:0035695;GO:0043231","-","-"]
["CAMK2A",1.807047,22.061646,3.609834498,0,0,"up","CAMK2A","calcium/calmodulin dependent protein kinase II alpha","GO:0000082;GO:0000166;GO:0002931;GO:0004672;GO:0004674;GO:0004683;GO:0005516;GO:0005524;GO:0005737;GO:0005739;GO:0005954;GO:0006468;GO:0006816;GO:0007399;GO:0009931;GO:0010666;GO:0014069;GO:0016301;GO:0018105;GO:0018107;GO:0030154;GO:0035254;GO:0035556;GO:0038166;GO:0042802;GO:0042803;GO:0043005;GO:0043197;GO:0046777;GO:0046928;GO:0048168;GO:0048813;GO:0051092;GO:0051928;GO:0060996;GO:0098685;GO:0099148;GO:1902108;GO:1990443;GO:2001222","K04515-ko04012 ErbB signaling pathway;ko04310 Wnt signaling pathway;ko04066 HIF-1 signaling pathway;ko04020 Calcium signaling pathway;ko04024 cAMP signaling pathway;ko04114 Oocyte meiosis;ko04911 Insulin secretion;ko04922 Glucagon signaling pathway;ko04912 GnRH signaling pathway;ko04921 Oxytocin signaling pathway;ko04916 Melanogenesis;ko04925 Aldosterone synthesis and secretion;ko04261 Adrenergic signaling in cardiomyocytes;ko04971 Gastric acid secretion;ko04725 Cholinergic synapse;ko04728 Dopaminergic synapse;ko04720 Long-term potentiation;ko04722 Neurotrophin signaling pathway;ko04745 Phototransduction - fly;ko04740 Olfactory transduction;ko04750 Inflammatory mediator regulation of TRP channels;ko04360 Axon guidance;ko04713 Circadian entrainment;ko05205 Proteoglycans in cancer;ko05214 Glioma;ko05031 Amphetamine addiction;ko05152 Tuberculosis","KOG0033-Ca2+/calmodulin-dependent protein kinase, EF-Hand protein superfamily[T]"]
["ALPK2",1.143029,13.893431,3.603469007,0,0,"up","ALPK2","-","-","-","-"]
["LOC112532134",0.90769,11.000423,3.599215527,{"v":1.14e-171,"d":"1.14E-171"},{"v":1.12e-170,"d":"1.12E-170"},"up","LOC112532134","-","-","-","-"]
["AOX2",6.6575,79.613724,3.579964719,0,0,"up","AOX2","aldehyde oxidase 2","GO:0004854;GO:0005506;GO:0005829;GO:0009055;GO:0009115;GO:0016491;GO:0016903;GO:0022900;GO:0046872;GO:0050660;GO:0051287;GO:0051536;GO:0051537;GO:0055114;GO:0071949","K00157-ko00280 Valine, leucine and isoleucine degradation;ko00350 Tyrosine metabolism;ko00380 Tryptophan metabolism;ko00750 Vitamin B6 metabolism;ko00760 Nicotinate and nicotinamide metabolism;ko00830 Retinol metabolism;ko00982 Drug metabolism - cytochrome P450;ko04630 Jak-STAT signaling pathway","KOG0430-Xanthine dehydrogenase[F]"]
["GIF",23.259129,277.360413,3.575892913,0,0,"up","GIF","-","GO:0005615;GO:0005768;GO:0005902;GO:0015889;GO:0016324;GO:0031419","-","-"]
["CCL20",2.037916,24.17696,3.56846636,{"v":1.53e-96,"d":"1.53E-96"},{"v":1.01e-95,"d":"1.01E-95"},"up","CCL20","C-C motif chemokine ligand 20","GO:0002548;GO:0005125;GO:0005576;GO:0005615;GO:0005622;GO:0006935;GO:0006954;GO:0006955;GO:0007186;GO:0008009;GO:0010469;GO:0030593;GO:0031731;GO:0035584;GO:0043547;GO:0048020;GO:0048247;GO:0060326;GO:0070098;GO:0070374;GO:0071346;GO:0071347;GO:0071356;GO:0072678;GO:0072679;GO:2000406","K14625-ko04668 TNF signaling pathway;ko04060 Cytokine-cytokine receptor interaction;ko04062 Chemokine signaling pathway;ko05323 Rheumatoid arthritis","-"]
["RALY",9.421546,111.523354,3.565238231,0,0,"up","RALY","-","GO:0003676;GO:0003712;GO:0003723;GO:0005634;GO:0042632;GO:0071013;GO:1903506","-","KOG0123-Polyadenylate-binding protein (RRM superfamily)[AJ]"]
["RSPH9",6.202335,73.392174,3.564742877,0,0,"up","RSPH9","radial spoke head 9 homolog","GO:0003341;GO:0005930;GO:0035082;GO:0044458;GO:0060294;GO:0097729","-","-"]
["CAMK4",1.100265,12.99161,3.561657284,{"v":9.47e-58,"d":"9.47E-58"},{"v":4.62e-57,"d":"4.62E-57"},"up","CAMK4","calcium/calmodulin dependent protein kinase IV","GO:0000166;GO:0001650;GO:0004672;GO:0004674;GO:0004683;GO:0005516;GO:0005524;GO:0005634;GO:0005654;GO:0005737;GO:0006468;GO:0007616;GO:0009931;GO:0018105;GO:0035556;GO:0043011;GO:0045893;GO:0046777","K05869-ko04020 Calcium signaling pathway;ko04024 cAMP signaling pathway;ko04921 Oxytocin signaling pathway;ko04925 Aldosterone synthesis and secretion;ko04725 Cholinergic synapse;ko04720 Long-term potentiation;ko04722 Neurotrophin signaling pathway;ko04380 Osteoclast differentiation;ko04211 Longevity regulating pathway - mammal;ko05031 Amphetamine addiction;ko05034 Alcoholism","KOG0032-Ca2+/calmodulin-dependent protein kinase, EF-Hand protein superfamily[T]"]
["LOC112532135",3.511041,41.383064,3.559069718,{"v":1.91e-82,"d":"1.91E-82"},{"v":1.13e-81,"d":"1.13E-81"},"up","LOC112532135","-","-","-","-"]
["FZD9",7.971376,93.526215,3.552470118,0,0,"up","FZD9","frizzled class receptor 9","GO:0004888;GO:0004930;GO:0005886;GO:0007165;GO:0007166;GO:0007186;GO:0007275;GO:0016020;GO:0016021;GO:0016055;GO:0017147;GO:0035567;GO:0042813;GO:0060070;GO:0001503;GO:0004888;GO:0005737;GO:0005886;GO:0007166;GO:0007275;GO:0007405;GO:0007611;GO:0009986;GO:0016020;GO:0016021;GO:0016055;GO:0017147;GO:0030183;GO:0030501;GO:0031527;GO:0042803;GO:0042813;GO:0043524;GO:0046982;GO:0048471;GO:0071157;GO:0090263;GO:1904393;GO:1904394;GO:1990523;GO:2000179","K02842-ko04310 Wnt signaling pathway;ko04390 Hippo signaling pathway;ko04150 mTOR signaling pathway;ko04550 Signaling pathways regulating pluripotency of stem cells;ko04916 Melanogenesis;ko05200 Pathways in cancer;ko05205 Proteoglycans in cancer;ko05217 Basal cell carcinoma;ko05224 Breast cancer;ko05166 HTLV-I infection","KOG3577-Smoothened and related G-protein-coupled receptors[T]"]
["C6H10ORF71",3.690982,42.974785,3.541413815,0,0,"up","C6H10ORF71","-","-","-","-"]
["ZMAT4",0.948788,10.943452,3.52783832,0,0,"up","ZMAT4","-","GO:0002039;GO:0003676;GO:0003723;GO:0005634;GO:0008270;GO:0046872;GO:0072332","-","-"]
["KLHL31",7.072131,81.412155,3.525027304,0,0,"up","KLHL31","-","GO:0004842;GO:0016567;GO:0031463","-","KOG4441-Proteins containing BTB/POZ and Kelch domains, involved in regulatory/signal transduction processes[TR]"]
["EDCH1",1.636953,18.833941,3.52425011,{"v":2.62e-34,"d":"2.62E-34"},{"v":9.76e-34,"d":"9.76E-34"},"up","EDCH1","epidermal differentiation protein containing cysteine histidine motifs 1","-","-","-"]
["ASB5",5.497977,62.970486,3.517703025,0,0,"up","ASB5","-","GO:0005622;GO:0016020;GO:0016021;GO:0016567;GO:0035556","-","KOG4177-Ankyrin[M]"]
["SLC9A2",0.760253,8.694965,3.515628711,{"v":2.51e-179,"d":"2.51E-179"},{"v":2.53e-178,"d":"2.53E-178"},"up","SLC9A2","solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2","GO:0005886;GO:0006811;GO:0006812;GO:0006814;GO:0006885;GO:0008104;GO:0015297;GO:0015299;GO:0015385;GO:0015386;GO:0016020;GO:0016021;GO:0051453;GO:0055085;GO:0071805;GO:0098719;GO:1902600","-","KOG1966-Sodium/hydrogen exchanger protein[P]"]
["LOC421415",0.662445,7.55684,3.511910493,{"v":1.24e-54,"d":"1.24E-54"},{"v":5.84e-54,"d":"5.84E-54"},"up","LOC421415","-","-","-","-"]
["RSPH10B",0.638265,7.273323,3.510387203,{"v":8.82e-142,"d":"8.82E-142"},{"v":7.53e-141,"d":"7.53E-141"},"up","RSPH10B","-","-","-","-"]
["SPAG6",1.367952,15.516614,3.503724257,{"v":2.47e-224,"d":"2.47E-224"},{"v":2.98e-223,"d":"2.98E-223"},"up","SPAG6","sperm associated antigen 6","GO:0015630","-","KOG0166-Karyopherin (importin) alpha[U]"]
["MYL1",718.899719,8123.74707,3.498282878,0,0,"up","MYL1","myosin, light chain 1, alkali; skeletal, fast","GO:0005509","-","KOG0030-Myosin essential light chain, EF-Hand protein superfamily[Z]"]
["C7",13.506224,152.312119,3.495334442,0,0,"up","C7","complement C7","GO:0005579;GO:0006955;GO:0006956","-","[KOG3475-60S ribosomal protein L37[J], KOG1480-Netrin transmembrane receptor unc-5[T]]"]
["SGCA",6.36933,71.393829,3.486585853,0,0,"up","SGCA","-","GO:0005509;GO:0005911;GO:0016011;GO:0016012;GO:0016020;GO:0016021;GO:0042383;GO:0045121","-","-"]
["DNAH3",1.105149,12.369983,3.484530721,0,0,"up","DNAH3","-","GO:0003341;GO:0003777;GO:0005524;GO:0007018;GO:0008569;GO:0016887;GO:0030286;GO:0036156;GO:0036159;GO:0045503;GO:0045505;GO:0051959","-","-"]
["LOC107051755",1.306744,14.576609,3.4796067,{"v":3.61e-200,"d":"3.61E-200"},{"v":3.97e-199,"d":"3.97E-199"},"up","LOC107051755","-","-","-","-"]
["MYH1F",19.254852,213.945251,3.473947716,0,0,"up","MYH1F","myosin, heavy chain 1F, skeletal muscle","GO:0000166;GO:0003774;GO:0003779;GO:0005524;GO:0016459;GO:0051015","K10352-ko04530 Tight junction","KOG0161-Myosin class II heavy chain[Z]"]
["RIPPLY2",0.825139,9.150758,3.471182177,{"v":2.97e-30,"d":"2.97E-30"},{"v":1.04e-29,"d":"1.04E-29"},"up","RIPPLY2","-","GO:0000122;GO:0001503;GO:0001756;GO:0005634;GO:0007219;GO:0007368;GO:0009798;GO:0009880;GO:0010468;GO:0032525;GO:0036342;GO:0060349","-","-"]
["TUBA8A",0.521467,5.764203,3.466473282,{"v":1.01e-72,"d":"1.01E-72"},{"v":5.56e-72,"d":"5.56E-72"},"up","TUBA8A","-","GO:0000166;GO:0003924;GO:0005200;GO:0005525;GO:0005737;GO:0005856;GO:0005874;GO:0007010;GO:0007017","K07374-ko04145 Phagosome;ko04210 Apoptosis;ko04540 Gap junction;ko05130 Pathogenic Escherichia coli infection","-"]
["SRCIN1",0.637728,7.017431,3.459929843,{"v":5.53e-166,"d":"5.53E-166"},{"v":5.3e-165,"d":"5.30E-165"},"up","SRCIN1","-","GO:0005737;GO:0015629;GO:0019901;GO:0030334;GO:0034446;GO:0061001;GO:0061098;GO:0061099","-","-"]
["S100B",0.465231,5.117262,3.459352963,{"v":1.28e-35,"d":"1.28E-35"},{"v":4.86e-35,"d":"4.86E-35"},"up","S100B","S100 calcium binding protein B","GO:0001726;GO:0005509;GO:0005634;GO:0005737;GO:0007611;GO:0007613;GO:0008270;GO:0042802;GO:0042803;GO:0043025;GO:0043123;GO:0044548;GO:0046872;GO:0048168;GO:0048306;GO:0048471;GO:0050786","-","-"]
["LOC107052924",0.737227,8.094791,3.456813018,{"v":2.32e-90,"d":"2.32E-90"},{"v":1.46e-89,"d":"1.46E-89"},"up","LOC107052924","-","-","-","-"]
["PAQR9",0.484406,5.318743,3.456796688,{"v":9.06e-187,"d":"9.06E-187"},{"v":9.42e-186,"d":"9.42E-186"},"up","PAQR9","-","GO:0016020;GO:0016021","-","KOG0748-Predicted membrane proteins, contain hemolysin III domain[RT]"]
["LPL",7.757127,84.899269,3.452157805,0,0,"up","LPL","lipoprotein lipase","GO:0004465;GO:0004806;GO:0005102;GO:0005576;GO:0005615;GO:0005886;GO:0006629;GO:0006633;GO:0008201;GO:0009617;GO:0009986;GO:0010744;GO:0010886;GO:0010890;GO:0016020;GO:0016042;GO:0016787;GO:0019432;GO:0019433;GO:0031225;GO:0034185;GO:0034361;GO:0034372;GO:0042627;GO:0042632;GO:0052689;GO:0055096;GO:0070328;GO:0090197","K01059-ko00561 Glycerolipid metabolism;ko03320 PPAR signaling pathway;ko05010 Alzheimer's disease","-"]
["TNNT3",255.217194,2784.808105,3.447780486,0,0,"up","TNNT3","troponin T3, fast skeletal type","GO:0003009;GO:0003779;GO:0005523;GO:0005861;GO:0006937;GO:0006942;GO:0030172;GO:0030899;GO:0031013;GO:0043462;GO:0048306","-","KOG3634-Troponin[Z]"]
["SRL",14.702244,160.097122,3.444839098,0,0,"up","SRL","sarcalumenin","GO:0002115;GO:0005525;GO:0014873;GO:0016529;GO:0033018","-","KOG1954-Endocytosis/signaling protein EHD1[TU]"]
["LOC107053690",0.921393,9.992962,3.439023826,{"v":1.28e-81,"d":"1.28E-81"},{"v":7.54e-81,"d":"7.54E-81"},"up","LOC107053690","-","-","-","-"]
["FBP2",4.362735,47.231911,3.436457158,0,0,"up","FBP2","-","GO:0005654;GO:0005829;GO:0005886;GO:0005975;GO:0005986;GO:0006000;GO:0006002;GO:0006094;GO:0016311;GO:0016787;GO:0016791;GO:0030388;GO:0042132;GO:0042578;GO:0042802","K03841-ko01200 Carbon metabolism;ko00010 Glycolysis / Gluconeogenesis;ko00030 Pentose phosphate pathway;ko00051 Fructose and mannose metabolism;ko00710 Carbon fixation in photosynthetic organisms;ko00680 Methane metabolism;ko04152 AMPK signaling pathway;ko04910 Insulin signaling pathway","KOG1458-Fructose-1,6-bisphosphatase[G]"]
["DCDC2B",6.922554,74.058365,3.419286392,0,0,"up","DCDC2B","-","-","-","-"]
["SLC16A3",2.216064,23.670362,3.417010318,{"v":5.57e-237,"d":"5.57E-237"},{"v":7.02e-236,"d":"7.02E-236"},"up","SLC16A3","solute carrier family 16 member 3","GO:0005886;GO:0005887;GO:0008028;GO:0015129;GO:0015718;GO:0016020;GO:0016021;GO:0031965;GO:0035873;GO:0055085;GO:0005886;GO:0005887;GO:0008028;GO:0015129;GO:0015293;GO:0015718;GO:0016020;GO:0016021;GO:0035873;GO:0055085;GO:0005886;GO:0005887;GO:0008028;GO:0015129;GO:0015293;GO:0015718;GO:0016020;GO:0016021;GO:0035873;GO:0055085","-","KOG2504-Monocarboxylate transporter[G]"]
["ERBB4",0.520135,5.537281,3.41221971,{"v":6.82e-263,"d":"6.82E-263"},{"v":9.3e-262,"d":"9.30E-262"},"up","ERBB4","erb-b2 receptor tyrosine kinase 4","GO:0000166;GO:0001755;GO:0004672;GO:0004713;GO:0004714;GO:0005154;GO:0005524;GO:0005634;GO:0005739;GO:0006468;GO:0007165;GO:0007169;GO:0007399;GO:0007416;GO:0007507;GO:0008284;GO:0008285;GO:0009880;GO:0010592;GO:0014068;GO:0016020;GO:0016021;GO:0016301;GO:0016310;GO:0016323;GO:0016477;GO:0016740;GO:0018108;GO:0021551;GO:0021889;GO:0030334;GO:0038083;GO:0042531;GO:0042803;GO:0043065;GO:0043066;GO:0043235;GO:0043653;GO:0044212;GO:0045165;GO:0045893;GO:0046427;GO:0046777;GO:0051491;GO:0060045;GO:0061026;GO:0070374;GO:0071364;GO:0098978;GO:0098982;GO:0099056;GO:0099061;GO:2000010;GO:2001223","K05085-ko04012 ErbB signaling pathway;ko04020 Calcium signaling pathway;ko04144 Endocytosis;ko05205 Proteoglycans in cancer","KOG1025-Epidermal growth factor receptor EGFR and related tyrosine kinases[T]"]
["GADD45G",4.169648,44.323544,3.410075738,{"v":1.62e-101,"d":"1.62E-101"},{"v":1.1e-100,"d":"1.10E-100"},"up","GADD45G","growth arrest and DNA damage inducible gamma","-","K04402-ko04010 MAPK signaling pathway;ko04068 FoxO signaling pathway;ko04110 Cell cycle;ko04210 Apoptosis;ko04115 p53 signaling pathway","-"]
["KCNH6",0.621596,6.580154,3.404072224,{"v":1.47e-125,"d":"1.47E-125"},{"v":1.15e-124,"d":"1.15E-124"},"up","KCNH6","potassium voltage-gated channel subfamily H member 6","GO:0005216;GO:0005244;GO:0005249;GO:0005267;GO:0005887;GO:0006811;GO:0006813;GO:0016020;GO:0016021;GO:0034765;GO:0042391;GO:0055085;GO:0071805;GO:0086091;GO:0005216;GO:0005244;GO:0005249;GO:0005267;GO:0006811;GO:0006813;GO:0016020;GO:0016021;GO:0034765;GO:0055085;GO:0071805","-","KOG0501-K+-channel KCNQ[P]"]
["SYPL2",22.328299,235.407242,3.39821345,0,0,"up","SYPL2","-","GO:0006874;GO:0008021;GO:0016020;GO:0016021","-","-"]
["FFAR4",0.706813,7.435954,3.395117366,{"v":7.37e-79,"d":"7.37E-79"},{"v":4.25e-78,"d":"4.25E-78"},"up","FFAR4","-","GO:0004930;GO:0005504;GO:0005886;GO:0005887;GO:0007186;GO:0008527;GO:0010827;GO:0016020;GO:0016021;GO:0030139;GO:0032870;GO:0034201;GO:0042277;GO:0043066;GO:0045444;GO:0046879;GO:0050710;GO:0050728;GO:0070374;GO:0070543;GO:0120162;GO:1901652;GO:1902656","-","KOG4219-G protein-coupled receptor[T]"]
["ENO4",0.674088,7.080396,3.392821203,{"v":1.42e-74,"d":"1.42E-74"},{"v":7.94e-74,"d":"7.94E-74"},"up","ENO4","-","GO:0000015;GO:0000287;GO:0004634;GO:0006096","K01689-ko01200 Carbon metabolism;ko01230 Biosynthesis of amino acids;ko00010 Glycolysis / Gluconeogenesis;ko00680 Methane metabolism;ko03018 RNA degradation;ko04066 HIF-1 signaling pathway","KOG2670-Enolase[G]"]
["SLC39A8",3.146709,33.003281,3.390693783,0,0,"up","SLC39A8","-","GO:0005385;GO:0005886;GO:0005887;GO:0006829;GO:0006882;GO:0016020;GO:0016021;GO:0030001;GO:0031090;GO:0046873;GO:0055085;GO:0070574;GO:0071578","-","KOG2693-Putative zinc transporter[P]"]
["ASB15",0.668271,7.003721,3.38961644,{"v":7.49e-76,"d":"7.49E-76"},{"v":4.23e-75,"d":"4.23E-75"},"up","ASB15","-","GO:0000151;GO:0004842;GO:0005634;GO:0005737;GO:0016567;GO:0031625;GO:0035556","-","KOG4177-Ankyrin[M]"]
["USP13",9.057757,94.654739,3.385448997,0,0,"up","USP13","ubiquitin specific peptidase 13 (isopeptidase T-3)","GO:0004197;GO:0004843;GO:0006355;GO:0006508;GO:0006511;GO:0006914;GO:0008233;GO:0008234;GO:0008270;GO:0008283;GO:0010506;GO:0016579;GO:0016787;GO:0031625;GO:0035523;GO:0036459;GO:0043130;GO:0044313;GO:0044389;GO:0046872;GO:0050821;GO:0051087;GO:0070536;GO:0070628;GO:1904288;GO:1904294;GO:1904378;GO:1904454","-","KOG0944-Ubiquitin-specific protease UBP14[O]"]
["RYR1L1",12.291363,127.769279,3.377824183,0,0,"up","RYR1L1","-","GO:0005623;GO:0006816;GO:0015278;GO:0051209","-","-"]
["MMD2",5.476649,56.907944,3.377264732,0,0,"up","MMD2","-","GO:0004672;GO:0006468;GO:0016020;GO:0016021;GO:0019835;GO:0032880;GO:0045666;GO:0045860;GO:0046579;GO:0048471","-","KOG4243-Macrophage maturation-associated protein[V]"]
["TMEM255A",20.223902,209.67334,3.374010151,0,0,"up","TMEM255A","-","GO:0009617;GO:0016020;GO:0016021","-","-"]
["ANK1",3.956208,40.759693,3.364953001,0,0,"up","ANK1","-","GO:0005737;GO:0005886;GO:0006888;GO:0007165;GO:0008093;GO:0014731;GO:0019899;GO:0030507;GO:0051117;GO:0072659","-","KOG4177-Ankyrin[M]"]
["PNPLA3",31.65126,325.729218,3.363338298,0,0,"up","PNPLA3","-","GO:0004806;GO:0006629;GO:0008152;GO:0010898;GO:0016042;GO:0016787","-","KOG3773-Adiponutrin and related vesicular transport proteins; predicted alpha/beta hydrolase[U]"]
["HSPB3",2.272323,23.374445,3.362692283,{"v":1.72e-245,"d":"1.72E-245"},{"v":2.22e-244,"d":"2.22E-244"},"up","HSPB3","-","GO:0005634;GO:0005737","-","KOG3591-Alpha crystallins[O]"]
["NRIP3",3.342988,34.377953,3.362273562,0,0,"up","NRIP3","-","GO:0004190;GO:0006508","-","KOG0012-DNA damage inducible protein[L]"]
["NR0B1",0.582018,5.980645,3.361165407,{"v":7.46e-32,"d":"7.46E-32"},{"v":2.68e-31,"d":"2.68E-31"},"up","NR0B1","nuclear receptor subfamily 0 group B member 1","GO:0000122;GO:0003677;GO:0003707;GO:0003714;GO:0003723;GO:0004879;GO:0005634;GO:0005737;GO:0005815;GO:0006351;GO:0006355;GO:0006694;GO:0007283;GO:0007530;GO:0008104;GO:0008134;GO:0008406;GO:0008584;GO:0016020;GO:0016607;GO:0019904;GO:0030154;GO:0030238;GO:0030325;GO:0030522;GO:0032448;GO:0033144;GO:0033327;GO:0035258;GO:0035902;GO:0042788;GO:0042803;GO:0043231;GO:0043401;GO:0043433;GO:0043565;GO:0045596;GO:0045892;GO:0060008","-","KOG4218-Nuclear hormone receptor betaFTZ-F1[K]"]
["LMOD3",4.65512,47.680435,3.356507135,0,0,"up","LMOD3","-","GO:0003779;GO:0003785;GO:0005523;GO:0005737;GO:0005865;GO:0006936;GO:0006941;GO:0007015;GO:0030239;GO:0030240;GO:0031430;GO:0031672;GO:0045010;GO:0048741;GO:0048743;GO:0051694","-","KOG3735-Tropomodulin and leiomodulin[Z]"]
["MATN3",8.875701,90.748817,3.353945864,0,0,"up","MATN3","matrilin 3","GO:0005509;GO:0005576;GO:0031012","-","KOG1214-Nidogen and related basement membrane protein proteins[MW]"]
["BHMT",6.065775,61.817448,3.349250207,0,0,"up","BHMT","-","GO:0005737;GO:0008168;GO:0008270;GO:0009086;GO:0016740;GO:0032259;GO:0046872;GO:0047150","K00544-ko00260 Glycine, serine and threonine metabolism;ko00270 Cysteine and methionine metabolism","-"]
["EYA2",0.869548,8.846803,3.346818624,{"v":9.45e-219,"d":"9.45E-219"},{"v":1.12e-217,"d":"1.12E-217"},"up","EYA2","EYA transcriptional coactivator and phosphatase 2","-","-","KOG3107-Predicted haloacid dehalogenase-like hydrolase (eyes absent)[R]"]
["TBX15",3.603952,36.656055,3.346399827,0,0,"up","TBX15","-","-","-","KOG3586-TBX1 and related T-box transcription factors[K]"]
["EEF1A2",211.047653,2142.402344,3.343588754,0,0,"up","EEF1A2","eukaryotic translation elongation factor 1 alpha 2","GO:0000166;GO:0003746;GO:0003924;GO:0005525;GO:0005622;GO:0005737;GO:0005853;GO:0006414;GO:0019901;GO:0043065;GO:0043209;GO:0045202;GO:0090218","K03231-ko03013 RNA transport;ko05134 Legionellosis","KOG0052-Translation elongation factor EF-1 alpha/Tu[J]"]
["LSMEM2",2.06957,21.002348,3.343147674,{"v":1.95e-108,"d":"1.95E-108"},{"v":1.38e-107,"d":"1.38E-107"},"up","LSMEM2","-","-","-","-"]
["CCDC27",2.890939,29.106359,3.331724307,0,0,"up","CCDC27","-","-","-","-"]
["PON2",3.123193,31.427696,3.330942881,0,0,"up","PON2","paraoxonase 2","GO:0004063;GO:0004064;GO:0005576;GO:0009636;GO:0016020;GO:0016311;GO:0016787;GO:0046872","-","-"]
["DOK5",1.536906,15.39096,3.323982387,{"v":6.67e-117,"d":"6.67E-117"},{"v":4.99e-116,"d":"4.99E-116"},"up","DOK5","-","GO:0007169;GO:0030182;GO:0043410;GO:0051386","-","KOG4047-Docking protein 1 (p62dok)[T]"]
["SPATA1",2.732041,27.351349,3.323560951,0,0,"up","SPATA1","-","-","-","-"]
["MYLK2",12.557517,125.29895,3.318751192,0,0,"up","MYLK2","myosin light chain kinase 2","GO:0004672;GO:0004687;GO:0005524;GO:0005634;GO:0005737;GO:0006468;GO:0006941;GO:0007274;GO:0010628;GO:0014816;GO:0018105;GO:0018107;GO:0032971;GO:0035556;GO:0035914;GO:0046777;GO:0055008","K00907-ko04020 Calcium signaling pathway;ko04022 cGMP - PKG signaling pathway;ko04810 Regulation of actin cytoskeleton;ko04510 Focal adhesion;ko04611 Platelet activation;ko04921 Oxytocin signaling pathway;ko04270 Vascular smooth muscle contraction;ko04971 Gastric acid secretion","KOG0032-Ca2+/calmodulin-dependent protein kinase, EF-Hand protein superfamily[T]"]
["CYP11A1",0.985014,9.743288,3.306192576,{"v":6.03e-76,"d":"6.03E-76"},{"v":3.41e-75,"d":"3.41E-75"},"up","CYP11A1","cytochrome P450 family 11 subfamily A member 1","GO:0004497;GO:0005506;GO:0005739;GO:0005743;GO:0006629;GO:0006694;GO:0006700;GO:0008202;GO:0008203;GO:0008207;GO:0008386;GO:0016020;GO:0016491;GO:0016705;GO:0020037;GO:0046872;GO:0055114","K00498-ko00140 Steroid hormone biosynthesis;ko04913 Ovarian Steroidogenesis;ko04925 Aldosterone synthesis and secretion","KOG0159-Cytochrome P450 CYP11/CYP12/CYP24/CYP27 subfamilies[Q]"]
["FBXO39",2.296731,22.503893,3.292520799,{"v":1.96e-264,"d":"1.96E-264"},{"v":2.69e-263,"d":"2.69E-263"},"up","FBXO39","-","-","-","-"]
["GABRP",2.019965,19.678677,3.284231031,{"v":4.38e-262,"d":"4.38E-262"},{"v":5.96e-261,"d":"5.96E-261"},"up","GABRP","-","GO:0004888;GO:0004890;GO:0005216;GO:0005230;GO:0005886;GO:0006811;GO:0016020;GO:0016021;GO:0034220;GO:1902711","K05189-ko04080 Neuroactive ligand-receptor interaction;ko04727 GABAergic synapse;ko04723 Retrograde endocannabinoid signaling;ko05032 Morphine addiction;ko05033 Nicotine addiction","KOG3643-GABA receptor[T]"]
["LOC112531313",0.580437,5.649837,3.282997854,{"v":1.1e-29,"d":"1.10E-29"},{"v":3.83e-29,"d":"3.83E-29"},"up","LOC112531313","-","-","-","-"]
["ASAH2",0.623088,6.045258,3.278296075,{"v":3.61e-211,"d":"3.61E-211"},{"v":4.15e-210,"d":"4.15E-210"},"up","ASAH2","-","GO:0016020;GO:0016021;GO:0017040","K12349-ko00600 Sphingolipid metabolism;ko04071 Sphingolipid signaling pathway","-"]
["BMF",0.851983,8.248546,3.275243284,{"v":3.64e-287,"d":"3.64E-287"},{"v":5.3e-286,"d":"5.30E-286"},"up","BMF","Bcl2 modifying factor","GO:0006915;GO:0010507;GO:0034644;GO:0043065;GO:0043276","-","-"]
["C2H8ORF22",2.882568,27.85113,3.272309316,{"v":5.45e-142,"d":"5.45E-142"},{"v":4.66e-141,"d":"4.66E-141"},"up","C2H8ORF22","chromosome 2 open reading frame, human C8orf22","GO:0007275;GO:0030154","-","-"]
["ADPRHL",4.896056,47.286907,3.271748815,{"v":1.15e-233,"d":"1.15E-233"},{"v":1.43e-232,"d":"1.43E-232"},"up","ADPRHL","-","-","-","-"]
["IRS2",11.711552,113.079079,3.27132786,0,0,"up","IRS2","-","-","K07187-ko04068 FoxO signaling pathway;ko04022 cGMP - PKG signaling pathway;ko04152 AMPK signaling pathway;ko04910 Insulin signaling pathway;ko04923 Regulation of lipolysis in adipocyte;ko04920 Adipocytokine signaling pathway;ko04211 Longevity regulating pathway - mammal;ko04213 Longevity regulating pathway - multiple species;ko05206 MicroRNAs in cancer;ko04930 Type II diabetes mellitus;ko04932 Non-alcoholic fatty liver disease (NAFLD);ko04931 Insulin resistance","-"]
["ZBTB32",7.076846,68.197128,3.268532554,0,0,"up","ZBTB32","zinc finger and BTB domain containing 32","GO:0000122;GO:0000980;GO:0001501;GO:0001823;GO:0003676;GO:0003677;GO:0005634;GO:0006355;GO:0007417;GO:0008285;GO:0009880;GO:0009952;GO:0016604;GO:0016605;GO:0016607;GO:0017053;GO:0030097;GO:0032332;GO:0032991;GO:0035116;GO:0035136;GO:0035137;GO:0042802;GO:0042803;GO:0043065;GO:0045600;GO:0045638;GO:0045778;GO:0045892;GO:0045893;GO:0048133;GO:0051138;GO:0051216;GO:0061036","-","-"]
["LOC112530294",6.463737,62.070766,3.263473547,0,0,"up","LOC112530294","-","-","-","-"]
["MOGAT2",2.24542,21.492748,3.258792726,{"v":3.54e-223,"d":"3.54E-223"},{"v":4.25e-222,"d":"4.25E-222"},"up","MOGAT2","-","GO:0003846;GO:0005783;GO:0006629;GO:0006651;GO:0016020;GO:0016021;GO:0016407;GO:0016747;GO:0019432;GO:0050892","K14457-ko00561 Glycerolipid metabolism;ko04975 Fat digestion and absorption","KOG0831-Acyl-CoA:diacylglycerol acyltransferase (DGAT)[I]"]
["KCNN1",2.197899,20.739876,3.238210272,{"v":7.85e-165,"d":"7.85E-165"},{"v":7.47e-164,"d":"7.47E-164"},"up","KCNN1","-","GO:0005516;GO:0006813;GO:0015269;GO:0016020;GO:0016021;GO:0016286;GO:0071805","-","KOG3684-Ca2+-activated K+ channel proteins (intermediate/small conductance classes)[P]"]
["CCDC60",1.683368,15.881163,3.237894064,{"v":7.52e-158,"d":"7.52E-158"},{"v":6.92e-157,"d":"6.92E-157"},"up","CCDC60","-","-","-","-"]
["TMEM38A",28.455721,267.222198,3.231249217,0,0,"up","TMEM38A","transmembrane protein 38A","GO:0005261;GO:0015672;GO:0016020;GO:0016021;GO:0034220;GO:0098655;GO:0005261;GO:0005267;GO:0005634;GO:0006811;GO:0006813;GO:0015269;GO:0015672;GO:0016020;GO:0016021;GO:0016529;GO:0031965;GO:0033017;GO:0071805","-","KOG3944-Uncharacterized conserved protein[S]"]
["LOC112530103",0.5947,5.576432,3.229108349,{"v":3.31e-48,"d":"3.31E-48"},{"v":1.46e-47,"d":"1.46E-47"},"up","LOC112530103","-","-","-","-"]
["LRG1",0.556349,5.198964,3.224162085,{"v":9.38e-33,"d":"9.38E-33"},{"v":3.42e-32,"d":"3.42E-32"},"up","LRG1","-","GO:0001938;GO:0005160;GO:0005615;GO:0007409;GO:0009617;GO:0030511;GO:0043231;GO:0045766","-","-"]
["NMRK2",14.935708,139.514923,3.223581913,0,0,"up","NMRK2","-","GO:0005622;GO:0005654;GO:0005886;GO:0043231;GO:0045662","K10524-ko00760 Nicotinate and nicotinamide metabolism","KOG3308-Uncharacterized protein of the uridine kinase family[F]"]
["MYH1C",3.140764,28.987902,3.206263475,0,0,"up","MYH1C","myosin, heavy chain 1C, skeletal muscle","GO:0000166;GO:0003774;GO:0003779;GO:0005524;GO:0016459;GO:0051015","K10352-ko04530 Tight junction","KOG0161-Myosin class II heavy chain[Z]"]
["MYO18B",4.048699,37.340031,3.20519283,0,0,"up","MYO18B","-","GO:0000166;GO:0001570;GO:0003774;GO:0003779;GO:0005524;GO:0016459;GO:0016461;GO:0030018;GO:0031941;GO:0048739","-","KOG0161-Myosin class II heavy chain[Z]"]
["P2RX5",1.423721,13.094683,3.201242774,{"v":1.92e-248,"d":"1.92E-248"},{"v":2.5e-247,"d":"2.50E-247"},"up","P2RX5","purinergic receptor P2X 5","GO:0001614;GO:0004931;GO:0005216;GO:0005524;GO:0005639;GO:0005887;GO:0006811;GO:0016020;GO:0016021;GO:0033198;GO:0035590;GO:0060079;GO:0098655;GO:0098794","K05219-ko04020 Calcium signaling pathway;ko04080 Neuroactive ligand-receptor interaction","-"]
["CFAP57",1.923958,17.524195,3.187198963,0,0,"up","CFAP57","-","-","-","KOG0266-WD40 repeat-containing protein[R]"]
["CMYA5",12.975031,117.889221,3.183621923,0,0,"up","CMYA5","-","-","-","KOG4367-Predicted Zn-finger protein[S]"]
["PPP1R17",4.916582,44.611881,3.181700369,0,0,"up","PPP1R17","-","GO:0004864;GO:0004865;GO:0005654;GO:0010921;GO:0032515","-","-"]
["SLC25A34",1.319044,11.950813,3.179544171,{"v":4.02e-67,"d":"4.02E-67"},{"v":2.12e-66,"d":"2.12E-66"},"up","SLC25A34","-","GO:0016020;GO:0016021","-","KOG0755-Mitochondrial oxaloacetate carrier protein[C]"]
["ABLIM2",4.447139,40.249809,3.178032534,0,0,"up","ABLIM2","-","GO:0003779;GO:0006351;GO:0007010;GO:0015629;GO:0030036;GO:0046872","-","KOG1044-Actin-binding LIM Zn-finger protein Limatin involved in axon guidance[TZ]"]
["LOC101752163",40.653744,367.595123,3.176657498,0,0,"up","LOC101752163","-","-","-","-"]
["ASB4",1.899717,17.085072,3.168879906,{"v":3.38e-154,"d":"3.38E-154"},{"v":3.06e-153,"d":"3.06E-153"},"up","ASB4","-","GO:0000151;GO:0004842;GO:0005634;GO:0005737;GO:0016567;GO:0031625;GO:0035556","-","KOG4177-Ankyrin[M]"]
["EYA1",1.319653,11.855359,3.16730882,{"v":9.43e-191,"d":"9.43E-191"},{"v":9.96e-190,"d":"9.96E-190"},"up","EYA1","-","GO:0001656;GO:0001657;GO:0001658;GO:0003151;GO:0003723;GO:0004721;GO:0004725;GO:0005634;GO:0005654;GO:0005737;GO:0006281;GO:0006302;GO:0006325;GO:0006351;GO:0006355;GO:0006470;GO:0006974;GO:0007275;GO:0007389;GO:0007501;GO:0007605;GO:0009887;GO:0010212;GO:0014706;GO:0016576;GO:0016604;GO:0016787;GO:0016925;GO:0030154;GO:0032991;GO:0032993;GO:0035335;GO:0035909;GO:0042471;GO:0042472;GO:0042473;GO:0042474;GO:0045165;GO:0045664;GO:0045739;GO:0045893;GO:0045944;GO:0046872;GO:0048665;GO:0048704;GO:0048752;GO:0048856;GO:0050679;GO:0060037;GO:0071599;GO:0071600;GO:0072513;GO:0090103;GO:2001240","-","KOG3107-Predicted haloacid dehalogenase-like hydrolase (eyes absent)[R]"]
["ACKR1",0.832384,7.454959,3.162879279,{"v":3.65e-68,"d":"3.65E-68"},{"v":1.94e-67,"d":"1.94E-67"},"up","ACKR1","-","-","-","-"]
["SLC25A4",265.31427,2375.663086,3.162556071,0,0,"up","SLC25A4","solute carrier family 25 member 4","GO:0016020;GO:0016021;GO:0005471;GO:0005739;GO:0005743;GO:0006979;GO:0008637;GO:0015866;GO:0015867;GO:0016020;GO:0016021;GO:0022857;GO:0022904;GO:0043209;GO:0046902;GO:0055085;GO:0060546","K05863-ko04020 Calcium signaling pathway;ko04022 cGMP - PKG signaling pathway;ko05012 Parkinson's disease;ko05016 Huntington's disease;ko05166 HTLV-I infection","KOG0749-Mitochondrial ADP/ATP carrier proteins[C]"]
["GLIPR1L",16.911388,151.339737,3.161723864,0,0,"up","GLIPR1L","GLI pathogenesis-related 1-like","GO:0005576;GO:0016020;GO:0016021","-","KOG3017-Defense-related protein containing SCP domain[S]"]
["CADM1",5.828744,52.120422,3.16059182,0,0,"up","CADM1","-","GO:0005102;GO:0005886;GO:0005887;GO:0005913;GO:0007156;GO:0007157;GO:0008037;GO:0016020;GO:0016021;GO:0034987;GO:0042271;GO:0042803;GO:0045954;GO:0050715;GO:0050839;GO:0051606","K06781-ko04514 Cell adhesion molecules (CAMs)","KOG4221-Receptor mediating netrin-dependent axon guidance[T]"]
["YIPF7",1.533651,13.635045,3.152277338,{"v":5.05e-72,"d":"5.05E-72"},{"v":2.77e-71,"d":"2.77E-71"},"up","YIPF7","Yip1 domain family member 7","GO:0016020;GO:0016021","-","KOG3103-Rab GTPase interacting factor, Golgi membrane protein[U]"]
["PPP1R1A",5.57361,49.349586,3.14635402,0,0,"up","PPP1R1A","-","-","K08050-ko04261 Adrenergic signaling in cardiomyocytes;ko04720 Long-term potentiation","-"]
["LOC101749448",0.696431,6.16395,3.145802831,{"v":4.95e-134,"d":"4.95E-134"},{"v":4.07e-133,"d":"4.07E-133"},"up","LOC101749448","-","-","-","-"]
["NEXN",18.140928,160.414902,3.144488005,0,0,"up","NEXN","-","GO:0008307;GO:0030018;GO:0030334;GO:0048739;GO:0051015;GO:0051493","-","-"]
["FGF13",2.036228,17.963209,3.141074084,0,0,"up","FGF13","fibroblast growth factor 13","GO:0005576;GO:0008083;GO:0010469;GO:0000165;GO:0005576;GO:0005634;GO:0005737;GO:0005829;GO:0005874;GO:0005886;GO:0006814;GO:0007026;GO:0007612;GO:0007613;GO:0008017;GO:0008083;GO:0010469;GO:0014704;GO:0016328;GO:0017080;GO:0021766;GO:0021795;GO:0030175;GO:0030295;GO:0030424;GO:0030425;GO:0030426;GO:0032147;GO:0043005;GO:0044325;GO:0046785;GO:0048487;GO:0072659;GO:0098909","-","KOG3885-Fibroblast growth factor[T]"]
["SBK2",1.83933,16.222925,3.140781715,{"v":4.98e-238,"d":"4.98E-238"},{"v":6.29e-237,"d":"6.29E-237"},"up","SBK2","-","GO:0000166;GO:0004672;GO:0004674;GO:0005524;GO:0005737;GO:0006468;GO:0007266;GO:0007346;GO:0016477;GO:0023014;GO:0030036;GO:0031098;GO:0032147;GO:0042981;GO:0043408;GO:0048365","-","KOG1345-Serine/threonine kinase[T]"]
["KIF20AL",0.691813,6.076409,3.134764951,{"v":2.9e-94,"d":"2.90E-94"},{"v":1.87e-93,"d":"1.87E-93"},"up","KIF20AL","-","GO:0000166;GO:0003774;GO:0003777;GO:0005524;GO:0005871;GO:0005874;GO:0007018;GO:0008017;GO:0016887","-","-"]
["FGF16",2.686984,23.519964,3.129826216,{"v":2e-62,"d":"2.00E-62"},{"v":1.01e-61,"d":"1.01E-61"},"up","FGF16","fibroblast growth factor 16","-","K04358-ko04014 Ras signaling pathway;ko04015 Rap1 signaling pathway;ko04010 MAPK signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04810 Regulation of actin cytoskeleton;ko05200 Pathways in cancer;ko05218 Melanoma;ko05224 Breast cancer","KOG3885-Fibroblast growth factor[T]"]
["RBP7",60.022205,522.59021,3.122111874,0,0,"up","RBP7","-","GO:0005501;GO:0008289","-","KOG4015-Fatty acid-binding protein FABP[I]"]
["SPAG16",1.488061,12.914202,3.117452925,{"v":4.81e-111,"d":"4.81E-111"},{"v":3.46e-110,"d":"3.46E-110"},"up","SPAG16","-","GO:0005634;GO:0005737;GO:0005930;GO:0007288;GO:0035082;GO:0051012;GO:0060271;GO:0060294;GO:0097231;GO:1990716","-","KOG0266-WD40 repeat-containing protein[R]"]
["PRR33",20.404861,175.610855,3.105397237,0,0,"up","PRR33","-","-","-","-"]
["LOC415324",5.18592,44.427048,3.098766427,{"v":3.11e-233,"d":"3.11E-233"},{"v":3.86e-232,"d":"3.86E-232"},"up","LOC415324","epididymal protein-like","-","-","-"]
["CAV3",2.581638,22.046839,3.094213198,{"v":1.23e-96,"d":"1.23E-96"},{"v":8.11e-96,"d":"8.11E-96"},"up","CAV3","caveolin 3","GO:0000139;GO:0001778;GO:0002027;GO:0005246;GO:0005783;GO:0005794;GO:0005886;GO:0005901;GO:0006469;GO:0006641;GO:0006897;GO:0007009;GO:0007015;GO:0007520;GO:0008022;GO:0008104;GO:0010614;GO:0010831;GO:0014819;GO:0014902;GO:0016010;GO:0016020;GO:0016021;GO:0017015;GO:0017080;GO:0023051;GO:0030315;GO:0031122;GO:0031579;GO:0032947;GO:0035995;GO:0038009;GO:0042383;GO:0042391;GO:0042593;GO:0042632;GO:0043014;GO:0043231;GO:0043407;GO:0043409;GO:0044325;GO:0044877;GO:0045121;GO:0045792;GO:0046716;GO:0051001;GO:0051394;GO:0051647;GO:0051896;GO:0051924;GO:0051926;GO:0055013;GO:0055117;GO:0060299;GO:0060307;GO:0060347;GO:0060373;GO:0060762;GO:0070836;GO:0071253;GO:0072659;GO:0090279;GO:0098909;GO:1900744;GO:1900825;GO:1900826;GO:1901019;GO:2000649","K12959-ko04144 Endocytosis;ko04510 Focal adhesion;ko05205 Proteoglycans in cancer;ko05100 Bacterial invasion of epithelial cells","-"]
["C4H4orf54",3.607647,30.749254,3.091421324,0,0,"up","C4H4orf54","-","-","-","-"]
["LOC423719",1.532397,13.037335,3.088786983,{"v":7.79e-108,"d":"7.79E-108"},{"v":5.48e-107,"d":"5.48E-107"},"up","LOC423719","-","-","-","-"]
["JPH1",13.652818,115.969406,3.086473591,0,0,"up","JPH1","-","GO:0005634;GO:0005654;GO:0005783;GO:0005789;GO:0005886;GO:0007517;GO:0008307;GO:0014701;GO:0016020;GO:0016021;GO:0016529;GO:0030018;GO:0030314","-","KOG0231-Junctional membrane complex protein Junctophilin and related MORN repeat proteins[R]"]
["LDLRAD1",0.951084,8.068087,3.08458197,{"v":1.48e-112,"d":"1.48E-112"},{"v":1.07e-111,"d":"1.07E-111"},"up","LDLRAD1","-","-","-","-"]
["SMTNL2",2.90642,24.567904,3.079459676,0,0,"up","SMTNL2","-","-","-","KOG0035-Ca2+-binding actin-bundling protein (actinin), alpha chain (EF-Hand protein superfamily)[Z]"]
["MYH1E",1.896822,15.865139,3.064203955,0,0,"up","MYH1E","myosin, heavy chain 1E, skeletal muscle","GO:0000166;GO:0003774;GO:0003779;GO:0005524;GO:0016459;GO:0051015","K10352-ko04530 Tight junction","KOG0161-Myosin class II heavy chain[Z]"]
["EFCAB5",1.271004,10.610331,3.061429187,{"v":2.25e-294,"d":"2.25E-294"},{"v":3.36e-293,"d":"3.36E-293"},"up","EFCAB5","-","GO:0005509","-","-"]
["MAFA",1.648277,13.645897,3.049436613,{"v":2.34e-120,"d":"2.34E-120"},{"v":1.78e-119,"d":"1.78E-119"},"up","MAFA","MAF bZIP transcription factor A","GO:0000978;GO:0003677;GO:0003700;GO:0005634;GO:0006351;GO:0006355;GO:0006366;GO:0007263;GO:0009749;GO:0030073;GO:0045893;GO:0045944","-","KOG4196-bZIP transcription factor MafK[K]"]
["DUSP27",1.210209,9.995955,3.046088188,0,0,"up","DUSP27","-","GO:0006470;GO:0008138;GO:0016311;GO:0016791","-","KOG1716-Dual specificity phosphatase[V]"]
["TPTE2",2.097042,17.280077,3.042681985,{"v":9.28e-127,"d":"9.28E-127"},{"v":7.33e-126,"d":"7.33E-126"},"up","TPTE2","-","GO:0004721;GO:0004725;GO:0005216;GO:0006470;GO:0006811;GO:0008138;GO:0016020;GO:0016021;GO:0016311;GO:0016787;GO:0034220;GO:0035335;GO:0055085","-","-"]
["MUSTN1",165.065826,1356.535522,3.038813455,0,0,"up","MUSTN1","musculoskeletal, embryonic nuclear protein 1","GO:0002062;GO:0003674;GO:0005634;GO:0008150;GO:0010628;GO:0032332;GO:0035988;GO:0042246;GO:1902730;GO:1902732","-","-"]
["PDK4",82.281792,675.108459,3.036474176,0,0,"up","PDK4","pyruvate dehydrogenase kinase, isozyme 4","GO:0004672;GO:0005524;GO:0006468;GO:0006885;GO:0008286;GO:0009267;GO:0010510;GO:0010565;GO:0010906;GO:0042304;GO:0042593;GO:0042594;GO:0045124;GO:0046320;GO:0071398;GO:0072593;GO:2000811","-","KOG0787-Dehydrogenase kinase[T]"]
["CEP350L",4.677273,38.127522,3.027093227,0,0,"up","CEP350L","-","-","-","-"]
["FEM1C",1.835417,14.882654,3.019452042,0,0,"up","FEM1C","-","GO:0005654;GO:0005829","-","KOG0508-Ankyrin repeat protein[R]"]
["ADAMTS20",0.95121,7.692578,3.01563138,{"v":1.76e-241,"d":"1.76E-241"},{"v":2.25e-240,"d":"2.25E-240"},"up","ADAMTS20","-","GO:0004175;GO:0004222;GO:0005615;GO:0006508;GO:0008237;GO:0008270;GO:0009967;GO:0030198;GO:0043066;GO:0045636;GO:0048070","-","KOG3538-Disintegrin metalloproteinases with thrombospondin repeats[O]"]
["SIK1",9.07274,73.175911,3.011758581,0,0,"up","SIK1","salt inducible kinase 1","GO:0000287;GO:0004672;GO:0004674;GO:0005524;GO:0005634;GO:0005737;GO:0006468;GO:0007346;GO:0008140;GO:0010830;GO:0010868;GO:0019901;GO:0032792;GO:0035556;GO:0042826;GO:0043153;GO:0043276;GO:0045595;GO:0045721;GO:0055007","-","KOG0586-Serine/threonine protein kinase[R]"]
["GFRA3",0.752884,6.019767,2.999208142,{"v":7.18e-139,"d":"7.18E-139"},{"v":6.02e-138,"d":"6.02E-138"},"up","GFRA3","-","GO:0001764;GO:0005829;GO:0005886;GO:0007411;GO:0008046;GO:0009897;GO:0038023;GO:0048485;GO:0048666","-","-"]
["LOC107053315",12.213302,97.383995,2.995231384,{"v":5.71e-290,"d":"5.71E-290"},{"v":8.38e-289,"d":"8.38E-289"},"up","LOC107053315","-","-","-","-"]
["PERM1",2.260179,17.927177,2.987639385,{"v":3.27e-235,"d":"3.27E-235"},{"v":4.09e-234,"d":"4.09E-234"},"up","PERM1","-","-","-","-"]
["MKX",0.901891,7.148283,2.986571763,{"v":1.62e-115,"d":"1.62E-115"},{"v":1.2e-114,"d":"1.20E-114"},"up","MKX","-","GO:0003677;GO:0005634;GO:0006355;GO:0043565","-","KOG0773-Transcription factor MEIS1 and related HOX domain proteins[K]"]
["PTP4A3",8.729422,69.186455,2.986531584,0,0,"up","PTP4A3","-","GO:0005634;GO:0005737;GO:0006355;GO:0006470;GO:0007219;GO:0008138;GO:0016311;GO:0016791;GO:0043117;GO:0043542;GO:1900746;GO:1901224;GO:1904951;GO:1990830","-","KOG2836-Protein tyrosine phosphatase IVA1[T]"]
["SPAG17",1.077854,8.454127,2.971494013,{"v":6.35e-279,"d":"6.35E-279"},{"v":9.06e-278,"d":"9.06E-278"},"up","SPAG17","-","-","-","-"]
["MYH1B",58.491291,458.107513,2.969392486,0,0,"up","MYH1B","myosin, heavy chain 1B, skeletal muscle","GO:0000166;GO:0003774;GO:0003779;GO:0005524;GO:0016459;GO:0051015;GO:0000166;GO:0003774;GO:0003779;GO:0005516;GO:0005524;GO:0005737;GO:0016459;GO:0030016;GO:0032982;GO:0051015","K10352-ko04530 Tight junction","KOG0161-Myosin class II heavy chain[Z]"]
["COL12A1",6.731157,52.497997,2.963335967,0,0,"up","COL12A1","collagen type XII alpha 1 chain","GO:0005576;GO:0005581;GO:0005595;GO:0007155;GO:0030199;GO:0035987;GO:0062023","-","KOG4221-Receptor mediating netrin-dependent axon guidance[T]"]
["LOC100858814",2.859246,22.281879,2.962164243,{"v":6.84e-65,"d":"6.84E-65"},{"v":3.53e-64,"d":"3.53E-64"},"up","LOC100858814","-","GO:0003999;GO:0006168;GO:0009116","-","-"]
["LOC112531292",62.597092,485.71524,2.955943211,{"v":5.63e-306,"d":"5.63E-306"},{"v":8.68e-305,"d":"8.68E-305"},"up","LOC112531292","-","-","-","-"]
["FHL1",167.990692,1302.855835,2.95522425,0,0,"up","FHL1","-","GO:0003254;GO:0005634;GO:0005737;GO:0005829;GO:0005886;GO:0010972;GO:0030308;GO:0043268;GO:0044325;GO:0046872;GO:1901016;GO:2000134","-","KOG2272-Focal adhesion protein PINCH-1, contains LIM domains[TZ]"]
["RADIL",1.152408,8.909907,2.950758792,{"v":6.32e-201,"d":"6.32E-201"},{"v":7e-200,"d":"7.00E-200"},"up","RADIL","-","GO:0005874;GO:0007165;GO:0034446","-","-"]
["LOC112530022",0.761564,5.868802,2.946028848,0,0,"up","LOC112530022","-","-","-","-"]
["SIX1",10.995173,84.479866,2.941737242,0,0,"up","SIX1","SIX homeobox 1","GO:0003700;GO:0006355;GO:0006915;GO:0008283;GO:0048513","-","KOG0775-Transcription factor SIX and related HOX domain proteins[K]"]
["YBEY",2.298532,17.602497,2.93699544,{"v":7.39e-229,"d":"7.39E-229"},{"v":9.05e-228,"d":"9.05E-228"},"up","YBEY","-","GO:0004222;GO:0005634;GO:0006364;GO:0006508","-","-"]
["PLPPR1",1.565401,11.969298,2.934734364,{"v":1.25e-81,"d":"1.25E-81"},{"v":7.36e-81,"d":"7.36E-81"},"up","PLPPR1","-","GO:0005654;GO:0005887;GO:0006644;GO:0007165;GO:0007399;GO:0008195;GO:0016020;GO:0016021;GO:0042577;GO:0046839","-","KOG3030-Lipid phosphate phosphatase and related enzymes of the PAP2 family[I]"]
["AMH",0.984035,7.491552,2.928483093,{"v":2.64e-84,"d":"2.64E-84"},{"v":1.59e-83,"d":"1.59E-83"},"up","AMH","anti-Mullerian hormone","GO:0001880;GO:0005102;GO:0005576;GO:0008083;GO:0008406;GO:0010469;GO:0010628","K04665-ko04350 TGF-beta signaling pathway;ko04390 Hippo signaling pathway;ko04024 cAMP signaling pathway;ko04060 Cytokine-cytokine receptor interaction","KOG3900-Transforming growth factor beta, bone morphogenetic protein and related proteins[T]"]
["SNX8",2.430155,18.403044,2.920824179,0,0,"up","SNX8","-","GO:0005768;GO:0005829;GO:0006886;GO:0006897;GO:0016050;GO:0019898;GO:0030904;GO:0031901;GO:0034498;GO:0035091;GO:0042147;GO:0042802;GO:0043231","-","KOG2273-Membrane coat complex Retromer, subunit VPS5/SNX1, Sorting nexins, and related PX domain-containing proteins[U]"]
["ACACB",3.65879,27.352657,2.902242463,0,0,"up","ACACB","-","GO:0000166;GO:0003989;GO:0004075;GO:0005524;GO:0006633;GO:0016874;GO:0046872","K01946-ko00620 Pyruvate metabolism;ko00640 Propanoate metabolism;ko00061 Fatty acid biosynthesis;ko00254 Aflatoxin biosynthesis;ko04910 Insulin signaling pathway;ko04922 Glucagon signaling pathway;ko04920 Adipocytokine signaling pathway;ko04931 Insulin resistance","-"]
["FOXC2",1.492452,11.143429,2.900436802,{"v":3.07e-75,"d":"3.07E-75"},{"v":1.72e-74,"d":"1.72E-74"},"up","FOXC2","forkhead box C2","-","-","-"]
["LOC107056410",1.524251,11.358954,2.897657591,{"v":6.82e-20,"d":"6.82E-20"},{"v":1.97e-19,"d":"1.97E-19"},"up","LOC107056410","-","-","-","-"]
["HTR6",2.099062,15.634535,2.896919626,0,0,"up","HTR6","5-hydroxytryptamine receptor 6","GO:0004930;GO:0004993;GO:0005929;GO:0007165;GO:0007186;GO:0016020;GO:0016021;GO:0021795;GO:0030594;GO:0032008;GO:0098664","K04162-ko04020 Calcium signaling pathway;ko04024 cAMP signaling pathway;ko04080 Neuroactive ligand-receptor interaction;ko04726 Serotonergic synapse","KOG4220-Muscarinic acetylcholine receptor[T]"]
["LOC107050773",18.77405,139.508636,2.89354262,0,0,"up","LOC107050773","-","GO:0005509","-","-"]
["TTC12",2.95563,21.848,2.885963637,{"v":3.16e-191,"d":"3.16E-191"},{"v":3.35e-190,"d":"3.35E-190"},"up","TTC12","-","-","-","-"]
["CCDC13",0.990301,7.287115,2.879408757,{"v":7.05e-180,"d":"7.05E-180"},{"v":7.14e-179,"d":"7.14E-179"},"up","CCDC13","-","GO:0005634;GO:0005813;GO:0005829;GO:0006974;GO:0031122;GO:0034451;GO:1905515","-","-"]
["C26H1orf74",1.355025,9.960885,2.877954459,{"v":1.01e-50,"d":"1.01E-50"},{"v":4.57e-50,"d":"4.57E-50"},"up","C26H1orf74","-","-","-","-"]
["LOC107054098",3.558715,26.118687,2.875654069,0,0,"up","LOC107054098","-","-","-","-"]
["HSPB7",45.405788,333.18692,2.875383647,0,0,"up","HSPB7","-","GO:0005634;GO:0005654;GO:0005737;GO:0007507;GO:0015629;GO:0016235;GO:0031005","-","KOG3591-Alpha crystallins[O]"]
["NRAP",6.317706,46.309418,2.873832919,0,0,"up","NRAP","-","GO:0003779;GO:0005916;GO:0005927;GO:0017166;GO:0030016;GO:0046872;GO:0051371","-","KOG1702-Nebulin repeat protein[Z]"]
["SLITRK6",1.290923,9.430885,2.86899021,0,0,"up","SLITRK6","-","GO:0001964;GO:0002088;GO:0002093;GO:0005886;GO:0005887;GO:0007409;GO:0007416;GO:0007601;GO:0008344;GO:0009986;GO:0016020;GO:0016021;GO:0021562;GO:0031223;GO:0035264;GO:0042472;GO:0043010;GO:0048812;GO:0051965;GO:0060005;GO:0060007;GO:0060384;GO:0071944;GO:0090102","-","KOG4194-Membrane glycoprotein LIG-1[T]"]
["C2CD4A",1.950883,14.147799,2.858378465,{"v":7.37e-121,"d":"7.37E-121"},{"v":5.62e-120,"d":"5.62E-120"},"up","C2CD4A","-","GO:0005509;GO:0005544;GO:0005886;GO:0006906;GO:0017158;GO:0019905;GO:0030276;GO:0045202;GO:0048791;GO:0098793","-","-"]
["LOC416147",1.79932,13.003509,2.853377297,0,0,"up","LOC416147","-","-","-","-"]
["CACNG1",27.272495,196.475418,2.848830226,0,0,"up","CACNG1","calcium voltage-gated channel auxiliary subunit gamma 1","GO:0005244;GO:0005245;GO:0005262;GO:0005891;GO:0006811;GO:0006816;GO:0016020;GO:0016021;GO:0034765;GO:0070296;GO:0070588","K04866-ko04010 MAPK signaling pathway;ko04921 Oxytocin signaling pathway;ko04260 Cardiac muscle contraction;ko04261 Adrenergic signaling in cardiomyocytes;ko05410 Hypertrophic cardiomyopathy (HCM);ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC);ko05414 Dilated cardiomyopathy (DCM)","-"]
["ADAMTSL2",3.817673,27.493786,2.848340145,0,0,"up","ADAMTSL2","-","GO:0005576;GO:0006508;GO:0008233;GO:0030198;GO:0030512;GO:0031012;GO:0050436;GO:0060481","-","KOG3538-Disintegrin metalloproteinases with thrombospondin repeats[O]"]
["ACTA1",809.738159,5817.296875,2.84482156,0,0,"up","ACTA1","actin, alpha 1, skeletal muscle","GO:0000166;GO:0001725;GO:0005515;GO:0005524;GO:0005737;GO:0005856;GO:0005865;GO:0005884;GO:0030240;GO:0048741;GO:0000166;GO:0005524","-","KOG0676-Actin and related proteins[Z]"]
["ANKRD66",1.294213,9.286472,2.843055536,{"v":1.96e-54,"d":"1.96E-54"},{"v":9.22e-54,"d":"9.22E-54"},"up","ANKRD66","-","-","-","KOG4177-Ankyrin[M]"]
["LOC107050574",2.1615,15.366884,2.829719913,{"v":2e-262,"d":"2.00E-262"},{"v":2.72e-261,"d":"2.72E-261"},"up","LOC107050574","-","-","-","-"]
["MLF1",67.56295,478.617706,2.824569542,0,0,"up","MLF1","-","GO:0007050;GO:0019904","-","KOG4049-Proliferation-related protein MLF[S]"]
["ANO8",9.886642,69.974464,2.823276033,0,0,"up","ANO8","-","GO:0016020;GO:0016021","-","KOG2513-Protein required for meiotic chromosome segregation[D]"]
["TMEM233",1.491946,10.547871,2.821684608,{"v":2.57e-33,"d":"2.57E-33"},{"v":9.46e-33,"d":"9.46E-33"},"up","TMEM233","-","-","-","-"]
["LGR5",0.833517,5.874725,2.817237791,{"v":1.52e-128,"d":"1.52E-128"},{"v":1.21e-127,"d":"1.21E-127"},"up","LGR5","-","GO:0004888;GO:0004930;GO:0005887;GO:0007186;GO:0009994;GO:0016020;GO:0016021;GO:0016500;GO:0032588;GO:0042127;GO:0048839;GO:0090263;GO:2001013","-","KOG2087-Glycoprotein hormone receptor[T]"]
["LOC107055147",0.983284,6.92712,2.816575594,{"v":2.59e-120,"d":"2.59E-120"},{"v":1.97e-119,"d":"1.97E-119"},"up","LOC107055147","-","-","-","-"]
["SPTB",3.701064,26.036947,2.814548305,0,0,"up","SPTB","-","GO:0003779;GO:0005200;GO:0005543;GO:0005737;GO:0005856;GO:0007010;GO:0008091;GO:0051693","-","-"]
["PPP2R3B",2.862978,20.104551,2.811933627,{"v":1.35e-210,"d":"1.35E-210"},{"v":1.55e-209,"d":"1.55E-209"},"up","PPP2R3B","-","GO:0005509","K11583-ko03015 mRNA surveillance pathway;ko04071 Sphingolipid signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04152 AMPK signaling pathway;ko04261 Adrenergic signaling in cardiomyocytes;ko04728 Dopaminergic synapse","-"]
["CTHRC1",4.181217,29.353424,2.811533975,0,0,"up","CTHRC1","-","GO:0005109;GO:0005615;GO:0005737;GO:0017147;GO:0032092;GO:0033690;GO:0043932;GO:0045669;GO:0060071;GO:0060122;GO:0090090;GO:0090103;GO:0090177","-","-"]
["NT5DC2",51.005772,356.193481,2.803928691,0,0,"up","NT5DC2","-","GO:0016020;GO:0016021;GO:0046872","-","KOG2470-Similar to IMP-GMP specific 5'-nucleotidase[F]"]
["ALOX5AP",3.750879,26.092932,2.798358437,{"v":3.34e-124,"d":"3.34E-124"},{"v":2.6e-123,"d":"2.60E-123"},"up","ALOX5AP","arachidonate 5-lipoxygenase activating protein","GO:0002540;GO:0004364;GO:0004464;GO:0004602;GO:0005634;GO:0005635;GO:0005783;GO:0006691;GO:0008047;GO:0016020;GO:0016021;GO:0019370;GO:0043085;GO:0098869","-","-"]
["H2AFJ",4.139173,28.757515,2.796524561,{"v":2.07e-43,"d":"2.07E-43"},{"v":8.7e-43,"d":"8.70E-43"},"up","H2AFJ","H2A histone family, member J","GO:0000786;GO:0003677;GO:0005634;GO:0005694;GO:0046982","K11251-ko05322 Systemic lupus erythematosus;ko05034 Alcoholism","-"]
["ABCG1",1.075773,7.462819,2.794347011,{"v":4.11e-257,"d":"4.11E-257"},{"v":5.52e-256,"d":"5.52E-256"},"up","ABCG1","-","GO:0000166;GO:0005524;GO:0005548;GO:0005622;GO:0005739;GO:0005768;GO:0005886;GO:0006355;GO:0008203;GO:0009897;GO:0010033;GO:0010872;GO:0010875;GO:0010888;GO:0016020;GO:0016021;GO:0016887;GO:0017127;GO:0019534;GO:0030301;GO:0032367;GO:0033344;GO:0033700;GO:0033993;GO:0034041;GO:0034374;GO:0034375;GO:0034436;GO:0034437;GO:0042632;GO:0042803;GO:0042987;GO:0043531;GO:0043691;GO:0045542;GO:0046982;GO:0055037;GO:0055085;GO:0055091;GO:0071403;GO:1901998","K05679-ko02010 ABC transporters","KOG0061-Transporter, ABC superfamily (Breast cancer resistance protein)[Q]"]
["ASB16",6.34785,44.022411,2.793898218,{"v":1.43e-214,"d":"1.43E-214"},{"v":1.67e-213,"d":"1.67E-213"},"up","ASB16","-","GO:0005622;GO:0016567;GO:0035556","-","KOG4177-Ankyrin[M]"]
["UBXN10",4.487585,30.888271,2.783047946,{"v":8.15e-274,"d":"8.15E-274"},{"v":1.14e-272,"d":"1.14E-272"},"up","UBXN10","UBX domain protein 10","GO:0005929;GO:0030992;GO:0060271","-","-"]
["KY",1.575891,10.831799,2.781033217,{"v":2.24e-123,"d":"2.24E-123"},{"v":1.73e-122,"d":"1.73E-122"},"up","KY","kyphoscoliosis peptidase","-","-","-"]
["GAMT",5.356117,36.663769,2.775095721,{"v":3.21e-149,"d":"3.21E-149"},{"v":2.83e-148,"d":"2.83E-148"},"up","GAMT","-","GO:0006601;GO:0007283;GO:0009887;GO:0030731;GO:0032259;GO:0040014","K00542-ko00260 Glycine, serine and threonine metabolism;ko00330 Arginine and proline metabolism","-"]
["LOC112532478",1.166625,7.968481,2.77196384,{"v":2.18e-121,"d":"2.18E-121"},{"v":1.67e-120,"d":"1.67E-120"},"up","LOC112532478","-","-","-","-"]
["EPHA7",0.962122,6.537908,2.764537327,{"v":5.39e-98,"d":"5.39E-98"},{"v":3.57e-97,"d":"3.57E-97"},"up","EPHA7","EPH receptor A7","GO:0000166;GO:0001934;GO:0004672;GO:0004713;GO:0004714;GO:0005003;GO:0005004;GO:0005524;GO:0005886;GO:0005887;GO:0006468;GO:0006915;GO:0007169;GO:0007275;GO:0007399;GO:0007420;GO:0008046;GO:0016020;GO:0016021;GO:0016301;GO:0016310;GO:0016740;GO:0018108;GO:0022407;GO:0031290;GO:0031952;GO:0043281;GO:0043525;GO:0045499;GO:0048013;GO:0048671;GO:0048755;GO:0050730;GO:0050919;GO:0051964;GO:0070372;GO:0072178;GO:0098978;GO:0099175;GO:0000166;GO:0004672;GO:0004713;GO:0005003;GO:0005524;GO:0006468;GO:0007169;GO:0016020;GO:0016021;GO:0016301;GO:0016310;GO:0016740;GO:0018108;GO:0048013","-","KOG0196-Tyrosine kinase, EPH (ephrin) receptor family[T]"]
["LOC112530508",0.781906,5.311498,2.764051718,{"v":1.03e-40,"d":"1.03E-40"},{"v":4.21e-40,"d":"4.21E-40"},"up","LOC112530508","-","-","-","-"]
["ATOH8",11.553205,78.02034,2.755557157,{"v":2.19e-274,"d":"2.19E-274"},{"v":3.08e-273,"d":"3.08E-273"},"up","ATOH8","atonal bHLH transcription factor 8","GO:0001704;GO:0001937;GO:0003700;GO:0005634;GO:0005654;GO:0005737;GO:0006355;GO:0008134;GO:0010595;GO:0010628;GO:0010629;GO:0030154;GO:0033613;GO:0035148;GO:0045603;GO:0045892;GO:0045893;GO:0046983;GO:0051450;GO:0060395;GO:0070888","-","KOG3898-Transcription factor NeuroD and related HTH proteins[K]"]
["SDC2",39.149021,264.165253,2.754392578,0,0,"up","SDC2","syndecan 2","GO:0016020;GO:0016021;GO:0030165;GO:0042802;GO:0048814","K16336-ko04514 Cell adhesion molecules (CAMs);ko05205 Proteoglycans in cancer;ko05144 Malaria","-"]
["LOC107049847",3.344945,22.556698,2.753501498,{"v":1.24e-99,"d":"1.24E-99"},{"v":8.33e-99,"d":"8.33E-99"},"up","LOC107049847","-","-","-","-"]
["TXLNB",1.775101,11.958009,2.752004183,{"v":3.84e-217,"d":"3.84E-217"},{"v":4.52e-216,"d":"4.52E-216"},"up","TXLNB","taxilin beta","GO:0005615;GO:0005737;GO:0010976;GO:0019905;GO:0030017;GO:0005615;GO:0005737;GO:0010976;GO:0019905;GO:0030017","-","KOG1850-Myosin-like coiled-coil protein[Z]"]
["LRRC34",1.878053,12.632872,2.749872981,{"v":9.04e-160,"d":"9.04E-160"},{"v":8.41e-159,"d":"8.41E-159"},"up","LRRC34","-","-","-","[KOG4308-LRR-containing protein[S], KOG1909-Ran GTPase-activating protein[AYT]]"]
["TPPP3",80.629623,540.911072,2.746009547,0,0,"up","TPPP3","-","GO:0001578;GO:0015631;GO:0046785;GO:0048471;GO:0097427","-","KOG4070-Putative signal transduction protein p25[RT]"]
["RASAL1",3.473664,23.121876,2.734728339,{"v":3.12e-267,"d":"3.12E-267"},{"v":4.3e-266,"d":"4.30E-266"},"up","RASAL1","-","GO:0005096;GO:0005543;GO:0005829;GO:0005886;GO:0007165;GO:0035556;GO:0043087;GO:0043547;GO:0046580;GO:0071277;GO:1903861","-","KOG2059-Ras GTPase-activating protein[T]"]
["RPGRIP1L",1.441369,9.572371,2.731436591,{"v":1.26e-170,"d":"1.26E-170"},{"v":1.23e-169,"d":"1.23E-169"},"up","RPGRIP1L","-","-","-","-"]
["LYSMD4",3.134593,20.791758,2.729661708,{"v":7.43e-258,"d":"7.43E-258"},{"v":1e-256,"d":"1.00E-256"},"up","LYSMD4","-","GO:0016020;GO:0016021","-","KOG2850-Predicted peptidoglycan-binding protein, contains LysM domain[R]"]
["SNTA1",39.18486,258.82605,2.72361458,0,0,"up","SNTA1","-","GO:0002027;GO:0005198;GO:0005622;GO:0017080;GO:0032991;GO:0044325;GO:0050998;GO:0051117;GO:0060307;GO:0086005;GO:1902083;GO:1902305","-","KOG3551-Syntrophins (type beta)[W]"]
["EFCAB10",4.186666,27.58954,2.720247669,{"v":1.64e-65,"d":"1.64E-65"},{"v":8.48e-65,"d":"8.48E-65"},"up","EFCAB10","-","GO:0005509","-","-"]
["MSTN",0.917787,6.020259,2.713594278,{"v":3.8e-26,"d":"3.80E-26"},{"v":1.24e-25,"d":"1.24E-25"},"up","MSTN","myostatin","GO:0005102;GO:0005125;GO:0005160;GO:0005576;GO:0005615;GO:0005623;GO:0007179;GO:0007519;GO:0008083;GO:0008201;GO:0009792;GO:0010469;GO:0010862;GO:0033002;GO:0033673;GO:0040008;GO:0042802;GO:0042803;GO:0042981;GO:0043408;GO:0045595;GO:0045662;GO:0045893;GO:0046627;GO:0046716;GO:0048468;GO:0048632;GO:0051898;GO:0060395;GO:0071549;GO:1902723;GO:1902725;GO:2000818;GO:0005102;GO:0005576;GO:0005615;GO:0008083;GO:0010469;GO:0016020;GO:0016021;GO:0033002;GO:1902723;GO:1902725;GO:2000818","-","-"]
["FHOD1",7.379204,48.23587,2.708569282,0,0,"up","FHOD1","formin homology 2 domain containing 1","GO:0001725;GO:0005634;GO:0005829;GO:0007097;GO:0014704;GO:0019904;GO:0042802;GO:0043621;GO:0045944;GO:0051492;GO:0051496;GO:0051660","-","KOG1925-Rac1 GTPase effector FHOS[TZ]"]
["CLCNKB",0.962955,6.257724,2.700097743,{"v":2.51e-73,"d":"2.51E-73"},{"v":1.39e-72,"d":"1.39E-72"},"up","CLCNKB","-","GO:0005247;GO:0006821;GO:0016020;GO:0016021;GO:0055085;GO:1902476","-","-"]
["TVP23A",3.061647,19.785404,2.692056666,{"v":2.49e-86,"d":"2.49E-86"},{"v":1.52e-85,"d":"1.52E-85"},"up","TVP23A","-","GO:0009306;GO:0016020;GO:0016021;GO:0016192;GO:0030173","-","KOG3195-Uncharacterized membrane protein NPD008/CGI-148[R]"]
["KCNQ5",1.252416,8.017734,2.67848071,{"v":5.95e-227,"d":"5.95E-227"},{"v":7.25e-226,"d":"7.25E-226"},"up","KCNQ5","-","GO:0005216;GO:0005249;GO:0005267;GO:0005887;GO:0006811;GO:0006813;GO:0008076;GO:0016020;GO:0016021;GO:0030118;GO:0055085;GO:0071805","-","KOG1419-Voltage-gated K+ channel KCNQ[P]"]
["LOC101748328",1.975712,12.599439,2.672914933,{"v":5.9e-127,"d":"5.90E-127"},{"v":4.66e-126,"d":"4.66E-126"},"up","LOC101748328","-","-","-","-"]
["LOC425238",2.073405,13.205763,2.671093808,{"v":3.09e-52,"d":"3.09E-52"},{"v":1.42e-51,"d":"1.42E-51"},"up","LOC425238","-","GO:0016020;GO:0016021","-","-"]
["NR4A1",5.006039,31.773172,2.66606769,{"v":7.23e-283,"d":"7.23E-283"},{"v":1.04e-281,"d":"1.04E-281"},"up","NR4A1","-","GO:0003677;GO:0003700;GO:0003707;GO:0004879;GO:0005634;GO:0005829;GO:0006351;GO:0006355;GO:0008270;GO:0030522;GO:0031965;GO:0043401;GO:0043565;GO:0046872","K04465-ko04010 MAPK signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04925 Aldosterone synthesis and secretion","KOG4217-Nuclear receptors of the nerve growth factor-induced protein B type[K]"]
["TAAR1",1.657022,10.502361,2.664049029,{"v":3.56e-100,"d":"3.56E-100"},{"v":2.39e-99,"d":"2.39E-99"},"up","TAAR1","-","GO:0001594;GO:0004930;GO:0007165;GO:0007186;GO:0008227;GO:0016020;GO:0016021","K05051-ko04080 Neuroactive ligand-receptor interaction","-"]
["LOC101749471",101.961052,645.681946,2.662805524,0,0,"up","LOC101749471","-","-","-","-"]
["CD36",45.594292,286.926208,2.653754622,0,0,"up","CD36","CD36 molecule","GO:0006955;GO:0007166;GO:0016020;GO:0016021","K06259-ko04152 AMPK signaling pathway;ko04512 ECM-receptor interaction;ko04145 Phagosome;ko04640 Hematopoietic cell lineage;ko04920 Adipocytokine signaling pathway;ko03320 PPAR signaling pathway;ko04975 Fat digestion and absorption;ko04931 Insulin resistance;ko05144 Malaria","KOG3776-Plasma membrane glycoprotein CD36 and related membrane receptors[T]"]
["SOX21",5.098522,31.83651,2.6425312,{"v":1.45e-261,"d":"1.45E-261"},{"v":1.97e-260,"d":"1.97E-260"},"up","SOX21","-","GO:0000122;GO:0000978;GO:0003677;GO:0003700;GO:0005634;GO:0006351;GO:0006355;GO:0006366;GO:0042472;GO:0043565;GO:0043588;GO:0045595;GO:0045892;GO:0045944;GO:0048839;GO:0048863","-","KOG0527-HMG-box transcription factor[K]"]
["MHCIA9",2.106689,13.010777,2.626657865,{"v":8.36e-96,"d":"8.36E-96"},{"v":5.46e-95,"d":"5.46E-95"},"up","MHCIA9","-","-","-","-"]
["LOC112530451",7.850624,48.345181,2.622492855,{"v":4.2e-303,"d":"4.20E-303"},{"v":6.44e-302,"d":"6.44E-302"},"up","LOC112530451","-","-","-","-"]
["ZMYND12",1.570766,9.546354,2.60348156,{"v":2.01e-123,"d":"2.01E-123"},{"v":1.56e-122,"d":"1.56E-122"},"up","ZMYND12","-","GO:0005622","-","-"]
["MRAS",19.37505,117.723732,2.603133245,0,0,"up","MRAS","muscle RAS oncogene homolog","GO:0000166;GO:0003924;GO:0005525;GO:0007165;GO:0016020;GO:0030742;GO:1990830","K07831-ko04014 Ras signaling pathway;ko04015 Rap1 signaling pathway;ko04010 MAPK signaling pathway;ko04072 Phospholipase D signaling pathway;ko04810 Regulation of actin cytoskeleton;ko04530 Tight junction;ko05205 Proteoglycans in cancer;ko05166 HTLV-I infection","KOG0395-Ras-related GTPase[R]"]
["TOX",1.215922,7.369247,2.599466526,{"v":6.8e-98,"d":"6.80E-98"},{"v":4.5e-97,"d":"4.50E-97"},"up","TOX","thymocyte selection associated high mobility group box","GO:0030098;GO:0032825;GO:0048535;GO:0048541","-","KOG0381-HMG box-containing protein[R]"]
["ARHGEF1",1.405672,8.4781,2.592480989,{"v":6.64e-144,"d":"6.64E-144"},{"v":5.73e-143,"d":"5.73E-143"},"up","ARHGEF1","-","-","-","-"]
["OXTR",1.459993,8.781755,2.588547834,{"v":2.13e-37,"d":"2.13E-37"},{"v":8.26e-37,"d":"8.26E-37"},"up","OXTR","oxytocin receptor","GO:0001992;GO:0004930;GO:0004990;GO:0005000;GO:0005886;GO:0005887;GO:0007165;GO:0007186;GO:0016020;GO:0016021;GO:0032870;GO:0042277;GO:0045777;GO:0045907;GO:0120162;GO:1901652","K04229-ko04020 Calcium signaling pathway;ko04024 cAMP signaling pathway;ko04080 Neuroactive ligand-receptor interaction;ko04921 Oxytocin signaling pathway","KOG4219-G protein-coupled receptor[T]"]
["KIF6",0.90577,5.425668,2.582584109,{"v":2.33e-58,"d":"2.33E-58"},{"v":1.14e-57,"d":"1.14E-57"},"up","KIF6","-","GO:0000166;GO:0003774;GO:0003777;GO:0005524;GO:0005871;GO:0005874;GO:0007018;GO:0008017;GO:0016887","-","KOG4280-Kinesin-like protein[Z]"]
["LOC107055337",1.136065,6.791882,2.579766013,{"v":2.39e-95,"d":"2.39E-95"},{"v":1.55e-94,"d":"1.55E-94"},"up","LOC107055337","-","-","-","-"]
["GJA5",4.291342,25.47043,2.569322529,{"v":3.93e-191,"d":"3.93E-191"},{"v":4.16e-190,"d":"4.16E-190"},"up","GJA5","gap junction protein alpha 5","GO:0005886;GO:0005921;GO:0005922;GO:0007154;GO:0016020;GO:0016021;GO:0030054","-","-"]
["PM20D2",32.766468,193.161514,2.559515603,0,0,"up","PM20D2","-","GO:0005654;GO:0006508;GO:0008152;GO:0016787;GO:0016805;GO:0032268","-","-"]
["EFHC1",2.973062,17.411083,2.549984489,{"v":2.87e-155,"d":"2.87E-155"},{"v":2.61e-154,"d":"2.61E-154"},"up","EFHC1","-","GO:0000281;GO:0000922;GO:0005813;GO:0007052;GO:0021795;GO:0043014;GO:0051302;GO:0072686","-","KOG0043-Uncharacterized conserved protein, contains DM10 domain[S]"]
["SLC45A4",4.306222,25.072727,2.541624315,0,0,"up","SLC45A4","-","GO:0008506;GO:0015770;GO:0016020;GO:0016021;GO:0055085","-","KOG0637-Sucrose transporter and related proteins[G]"]
["TRIM7",3.514277,20.451069,2.54087644,{"v":9.3e-127,"d":"9.30E-127"},{"v":7.34e-126,"d":"7.34E-126"},"up","TRIM7","tripartite motif containing 7","-","-","KOG2177-Predicted E3 ubiquitin ligase[O]"]
["FAM149A",1.918738,11.162627,2.540446956,{"v":2.59e-205,"d":"2.59E-205"},{"v":2.94e-204,"d":"2.94E-204"},"up","FAM149A","-","-","-","-"]
["IL1RL1",16.282347,94.434364,2.536003272,0,0,"up","IL1RL1","interleukin 1 receptor like 1","GO:0002113;GO:0002114;GO:0002826;GO:0004908;GO:0007165;GO:0009897;GO:0016020;GO:0016021;GO:0019221;GO:0031012;GO:0032689;GO:0032754;GO:0038172;GO:0043032;GO:0043124;GO:0050729;GO:0090197","-","[KOG4222-Axon guidance receptor Dscam[T], KOG3513-Neural cell adhesion molecule L1[T]]"]
["COQ2",8.140771,47.18129,2.534977523,0,0,"up","COQ2","-","GO:0002083;GO:0004659;GO:0006071;GO:0006744;GO:0016020;GO:0016021;GO:0016765;GO:0031305","K06125-ko00130 Ubiquinone and other terpenoid-quinone biosynthesis","KOG1381-Para-hydroxybenzoate-polyprenyl transferase[H]"]
["MPP1",24.795937,143.526611,2.5331426,0,0,"up","MPP1","membrane palmitoylated protein 1","GO:0005622;GO:0005829;GO:0016020;GO:0016607;GO:0016740;GO:0030863;GO:0032420;GO:0042995;GO:0090022","-","KOG0609-Calcium/calmodulin-dependent serine protein kinase/membrane-associated guanylate kinase[T]"]
["ST8SIA2",2.516034,14.480014,2.524839674,{"v":6.79e-199,"d":"6.79E-199"},{"v":7.4e-198,"d":"7.40E-198"},"up","ST8SIA2","ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2","GO:0001574;GO:0003828;GO:0005769;GO:0005794;GO:0006486;GO:0006491;GO:0008373;GO:0009311;GO:0016020;GO:0016021;GO:0016740;GO:0016757;GO:0055037;GO:0097503","-","KOG2692-Sialyltransferase[G]"]
["TMEM106C",3.514849,20.143711,2.518794873,{"v":3.28e-141,"d":"3.28E-141"},{"v":2.78e-140,"d":"2.78E-140"},"up","TMEM106C","-","GO:0016020;GO:0016021","-","-"]
["LOC112533548",1.287178,7.352195,2.513963458,{"v":8.9e-40,"d":"8.90E-40"},{"v":3.58e-39,"d":"3.58E-39"},"up","LOC112533548","-","-","-","-"]
["ZNF106",6.308643,35.951408,2.510646656,0,0,"up","ZNF106","-","GO:0003676;GO:0005829;GO:0008270;GO:0008286;GO:0016020;GO:0017124;GO:0046872","-","KOG0281-Beta-TrCP (transducin repeats containing)/Slimb proteins[S]"]
["FKBP5",89.525475,509.987457,2.510091592,0,0,"up","FKBP5","FK506 binding protein 5","GO:0000413;GO:0003755;GO:0005528;GO:0005654;GO:0009617;GO:0016853;GO:0031072;GO:0061077","-","-"]
["LOC107052236",1.568201,8.924346,2.508635964,{"v":3.65e-14,"d":"3.65E-14"},{"v":9.19e-14,"d":"9.19E-14"},"up","LOC107052236","-","-","-","-"]
["SLC8A3",1.908129,10.836974,2.505731356,{"v":1.83e-243,"d":"1.83E-243"},{"v":2.35e-242,"d":"2.35E-242"},"up","SLC8A3","solute carrier family 8 (sodium/calcium exchanger), member 3","GO:0002244;GO:0005432;GO:0005741;GO:0005789;GO:0005887;GO:0006816;GO:0006851;GO:0006874;GO:0007154;GO:0007612;GO:0007613;GO:0014819;GO:0015368;GO:0016020;GO:0016021;GO:0030001;GO:0031226;GO:0031594;GO:0035725;GO:0042383;GO:0042552;GO:0048471;GO:0048709;GO:0051560;GO:0055085;GO:0060078;GO:0060291;GO:0070588;GO:0071456;GO:0099580","K05849-ko04020 Calcium signaling pathway;ko04022 cGMP - PKG signaling pathway;ko04974 Protein digestion and absorption;ko04740 Olfactory transduction","KOG1306-Ca2+/Na+ exchanger NCX1 and related proteins[PT]"]
["FSD2",2.094846,11.858715,2.501031594,{"v":4.49e-173,"d":"4.49E-173"},{"v":4.43e-172,"d":"4.43E-172"},"up","FSD2","-","-","-","-"]
["LOC416755",6.026511,34.098751,2.500323984,0,0,"up","LOC416755","-","GO:0016020;GO:0016021","-","-"]
["MAPK15",2.17102,12.2623,2.497784684,{"v":1.48e-198,"d":"1.48E-198"},{"v":1.61e-197,"d":"1.61E-197"},"up","MAPK15","-","GO:0000165;GO:0000166;GO:0003400;GO:0003682;GO:0004672;GO:0004674;GO:0004707;GO:0005524;GO:0005634;GO:0005737;GO:0005776;GO:0005794;GO:0005814;GO:0005911;GO:0006468;GO:0006974;GO:0007029;GO:0008284;GO:0010506;GO:0016301;GO:0016310;GO:0016740;GO:0030336;GO:0032212;GO:0036064;GO:0046777;GO:0051973;GO:0072687;GO:0090494;GO:1902017;GO:1904355;GO:1904491;GO:1905188;GO:1905832","-","-"]
["KCNJ2",2.864622,16.123272,2.492727863,{"v":2.47e-123,"d":"2.47E-123"},{"v":1.91e-122,"d":"1.91E-122"},"up","KCNJ2","potassium voltage-gated channel subfamily J member 2","GO:0005242;GO:0005244;GO:0005887;GO:0006811;GO:0006813;GO:0016020;GO:0016021;GO:0031224;GO:0034765;GO:0051289","-","KOG3827-Inward rectifier K+ channel[P]"]
["LOC107049937",6.852359,38.541634,2.491745095,{"v":1.15e-205,"d":"1.15E-205"},{"v":1.31e-204,"d":"1.31E-204"},"up","LOC107049937","-","-","-","-"]
["THRSP",15.200389,85.460739,2.491153548,{"v":3.64e-229,"d":"3.64E-229"},{"v":4.48e-228,"d":"4.48E-228"},"up","THRSP","thyroid hormone responsive","-","-","-"]
["ARID5B",5.998083,33.719971,2.491029904,0,0,"up","ARID5B","AT-rich interaction domain 5B","GO:0000122;GO:0000977;GO:0001227;GO:0001822;GO:0003677;GO:0003713;GO:0005634;GO:0006355;GO:0006807;GO:0008584;GO:0008585;GO:0009791;GO:0010761;GO:0030325;GO:0035264;GO:0044212;GO:0045444;GO:0048008;GO:0048468;GO:0048644;GO:0048705;GO:0051091;GO:0060021;GO:0060325;GO:0060612;GO:0060613;GO:1903508;GO:1990830;GO:0003677;GO:0003713;GO:0005634;GO:0006351;GO:0006355;GO:0006357;GO:0044212;GO:0051091;GO:0060612;GO:1903508","-","KOG2744-DNA-binding proteins Bright/BRCAA1/RBP1 and related proteins containing BRIGHT domain[K]"]
["DYNLRB2",3.820796,21.37273,2.483826063,{"v":2.25e-40,"d":"2.25E-40"},{"v":9.14e-40,"d":"9.14E-40"},"up","DYNLRB2","dynein light chain roadblock-type 2","GO:0003774;GO:0005737;GO:0005856;GO:0005868;GO:0005874;GO:0007018;GO:0030286;GO:0036157;GO:0045505","-","KOG4115-Dynein-associated protein Roadblock[DN]"]
["PRKCQ",3.787546,21.14773,2.481167497,0,0,"up","PRKCQ","-","GO:0000166;GO:0001772;GO:0004672;GO:0004674;GO:0004697;GO:0005524;GO:0005737;GO:0005815;GO:0005886;GO:0006355;GO:0006468;GO:0006509;GO:0016235;GO:0016301;GO:0016310;GO:0016740;GO:0032212;GO:0032740;GO:0032753;GO:0035556;GO:0042102;GO:0045086;GO:0046627;GO:0046872;GO:0050870;GO:0051092;GO:0051973;GO:0060326;GO:0070233;GO:0090330;GO:1904355;GO:2000318;GO:2000570","K18052-ko04064 NF-kappa B signaling pathway;ko04530 Tight junction;ko04660 T cell receptor signaling pathway;ko04920 Adipocytokine signaling pathway;ko04270 Vascular smooth muscle contraction;ko04750 Inflammatory mediator regulation of TRP channels;ko04931 Insulin resistance;ko05162 Measles","-"]
["PROM1L",8.908034,49.593269,2.476965356,0,0,"up","PROM1L","-","GO:0016020;GO:0016021","-","-"]
["ACSBG1",1.24301,6.919211,2.476769633,{"v":4.62e-41,"d":"4.62E-41"},{"v":1.89e-40,"d":"1.89E-40"},"up","ACSBG1","-","GO:0000038;GO:0001676;GO:0003824;GO:0004467;GO:0005737;GO:0008152;GO:0031957;GO:0051384","K15013-ko01212 Fatty acid metabolism;ko00061 Fatty acid biosynthesis;ko00071 Fatty acid degradation;ko04920 Adipocytokine signaling pathway;ko03320 PPAR signaling pathway","KOG1256-Long-chain acyl-CoA synthetases (AMP-forming)[I]"]
["DRP2",2.469051,13.73056,2.475361925,{"v":1.68e-224,"d":"1.68E-224"},{"v":2.02e-223,"d":"2.02E-223"},"up","DRP2","-","GO:0005886;GO:0008270;GO:0046872","-","KOG4286-Dystrophin-like protein[NTZ]"]
["LCA5",4.947551,27.354805,2.467007787,0,0,"up","LCA5","-","GO:0005929;GO:0044877","-","-"]
["RGCCL",17.29966,95.227608,2.46063621,0,0,"up","RGCCL","-","-","-","-"]
["LOC107052301",0.984674,5.39397,2.453629428,{"v":1.05e-16,"d":"1.05E-16"},{"v":2.84e-16,"d":"2.84E-16"},"up","LOC107052301","-","-","-","-"]
["CHCHD10",229.692749,1255.285767,2.450238613,0,0,"up","CHCHD10","-","GO:0005634;GO:0005739;GO:0007005","-","KOG4090-Uncharacterized conserved protein[S]"]
["MLIP",12.812828,69.991318,2.449587038,0,0,"up","MLIP","-","-","-","-"]
["TDH",8.017602,43.572639,2.442179786,0,0,"up","TDH","-","GO:0003824;GO:0006567;GO:0008743;GO:0042802;GO:0050662;GO:0055114","K15789-ko00260 Glycine, serine and threonine metabolism","-"]
["CYR61",17.455961,94.71389,2.439856232,0,0,"up","CYR61","cysteine rich angiogenic inducer 61","GO:0001558;GO:0001649;GO:0001934;GO:0002041;GO:0003181;GO:0003278;GO:0003281;GO:0005178;GO:0005520;GO:0005576;GO:0007155;GO:0007165;GO:0007267;GO:0008201;GO:0010518;GO:0010811;GO:0019838;GO:0030198;GO:0030335;GO:0030513;GO:0033690;GO:0043065;GO:0043066;GO:0043280;GO:0044319;GO:0045597;GO:0045669;GO:0045860;GO:0045944;GO:0050840;GO:0060413;GO:0060548;GO:0060591;GO:0061036;GO:0070372;GO:0072593;GO:0098609;GO:2000304;GO:0001558;GO:0001649;GO:0001934;GO:0002041;GO:0003181;GO:0003278;GO:0003281;GO:0005178;GO:0005520;GO:0005576;GO:0007155;GO:0010518;GO:0010811;GO:0030198;GO:0030335;GO:0030513;GO:0033690;GO:0043065;GO:0043066;GO:0043280;GO:0044319;GO:0045597;GO:0045669;GO:0045860;GO:0045944;GO:0050840;GO:0060413;GO:0060591;GO:0061036;GO:0070372;GO:0072593;GO:0098609;GO:2000304","-","-"]
["FMO3",38.927086,211.116669,2.439194236,0,0,"up","FMO3","flavin containing monooxygenase 3","GO:0004497;GO:0004499;GO:0005789;GO:0016020;GO:0016021;GO:0016491;GO:0050660;GO:0050661;GO:0055114","K00485-ko00982 Drug metabolism - cytochrome P450","KOG1399-Flavin-containing monooxygenase[Q]"]
["SYNE1",5.60905,30.400957,2.438288391,0,0,"up","SYNE1","-","GO:0005635;GO:0016020;GO:0016021;GO:0034993;GO:0051015;GO:0090286","-","KOG0517-Beta-spectrin[Z]"]
["PLCL2",3.672822,19.865513,2.435305166,0,0,"up","PLCL2","-","GO:0002322;GO:0002337;GO:0004435;GO:0005622;GO:0006629;GO:0007165;GO:0007214;GO:0008081;GO:0016042;GO:0016787;GO:0032228;GO:0033135;GO:0035556;GO:0050811;GO:0050859;GO:0070679;GO:0120163;GO:1900122","-","KOG0169-Phosphoinositide-specific phospholipase C[T]"]
["FOS",27.486076,147.954742,2.428383073,0,0,"up","FOS","Fos proto-oncogene, AP-1 transcription factor subunit","GO:0000978;GO:0000979;GO:0001102;GO:0003677;GO:0003682;GO:0003700;GO:0005634;GO:0005654;GO:0005667;GO:0005737;GO:0005783;GO:0005829;GO:0006355;GO:0006357;GO:0006366;GO:0007179;GO:0007399;GO:0008134;GO:0031668;GO:0032993;GO:0034614;GO:0035914;GO:0035976;GO:0035994;GO:0042493;GO:0044212;GO:0045672;GO:0045893;GO:0045944;GO:0046982;GO:0060395;GO:0070412;GO:0071276;GO:0071277","K04379-ko04010 MAPK signaling pathway;ko04668 TNF signaling pathway;ko04024 cAMP signaling pathway;ko04210 Apoptosis;ko04620 Toll-like receptor signaling pathway;ko04660 T cell receptor signaling pathway;ko04662 B cell receptor signaling pathway;ko04915 Estrogen signaling pathway;ko04917 Prolactin signaling pathway;ko04921 Oxytocin signaling pathway;ko04725 Cholinergic synapse;ko04728 Dopaminergic synapse;ko04380 Osteoclast differentiation;ko04713 Circadian entrainment;ko05200 Pathways in cancer;ko05231 Choline metabolism in cancer;ko05210 Colorectal cancer;ko05224 Breast cancer;ko05323 Rheumatoid arthritis;ko05031 Amphetamine addiction;ko05132 Salmonella infection;ko05133 Pertussis;ko05166 HTLV-I infection;ko05161 Hepatitis B;ko05168 Herpes simplex infection;ko05140 Leishmaniasis;ko05142 Chagas disease (American trypanosomiasis);ko01522 Endocrine resistance","KOG1414-Transcriptional activator FOSB/c-Fos and related bZIP transcription factors[K]"]
["CHGB",3.654469,19.60721,2.423650562,{"v":1.39e-152,"d":"1.39E-152"},{"v":1.25e-151,"d":"1.25E-151"},"up","CHGB","-","-","-","-"]
["NFASC",1.371723,7.349481,2.421653195,{"v":1.99e-189,"d":"1.99E-189"},{"v":2.09e-188,"d":"2.09E-188"},"up","NFASC","neurofascin","GO:0002175;GO:0005886;GO:0007155;GO:0007411;GO:0007422;GO:0016020;GO:0016021;GO:0019226;GO:0030424;GO:0030913;GO:0033010;GO:0033270;GO:0034113;GO:0042552;GO:0043194;GO:0043209;GO:0045162;GO:0050808;GO:0071205;GO:0086080","K06757-ko04514 Cell adhesion molecules (CAMs)","KOG3513-Neural cell adhesion molecule L1[T]"]
["ABCC5",15.169658,81.259232,2.421343169,0,0,"up","ABCC5","-","GO:0000166;GO:0005524;GO:0008514;GO:0015711;GO:0016020;GO:0016021;GO:0016887;GO:0042626;GO:0055085","K05668-ko02010 ABC transporters","KOG0054-Multidrug resistance-associated protein/mitoxantrone resistance protein, ABC superfamily[Q]"]
["PIK3R1",1.679296,8.989244,2.420343241,{"v":1.75e-202,"d":"1.75E-202"},{"v":1.95e-201,"d":"1.95E-201"},"up","PIK3R1","-","GO:0001678;GO:0001784;GO:0001953;GO:0005158;GO:0005159;GO:0005168;GO:0005634;GO:0005737;GO:0005801;GO:0005829;GO:0005911;GO:0005942;GO:0006468;GO:0006606;GO:0007162;GO:0008134;GO:0008286;GO:0008625;GO:0008630;GO:0014065;GO:0016020;GO:0019903;GO:0030183;GO:0030335;GO:0032760;GO:0032869;GO:0032991;GO:0033120;GO:0034644;GO:0034976;GO:0035014;GO:0036312;GO:0042307;GO:0043066;GO:0043125;GO:0043551;GO:0043559;GO:0043560;GO:0045671;GO:0045944;GO:0046626;GO:0046854;GO:0046935;GO:0046982;GO:0048009;GO:0050821;GO:0051492;GO:0060396;GO:1900103;GO:1903076;GO:1990578;GO:2001275","K02649-ko04014 Ras signaling pathway;ko04015 Rap1 signaling pathway;ko04012 ErbB signaling pathway;ko04370 VEGF signaling pathway;ko04630 Jak-STAT signaling pathway;ko04668 TNF signaling pathway;ko04066 HIF-1 signaling pathway;ko04068 FoxO signaling pathway;ko04070 Phosphatidylinositol signaling system;ko04072 Phospholipase D signaling pathway;ko04071 Sphingolipid signaling pathway;ko04024 cAMP signaling pathway;ko04022 cGMP - PKG signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04152 AMPK signaling pathway;ko04150 mTOR signaling pathway;ko04810 Regulation of actin cytoskeleton;ko04210 Apoptosis;ko04510 Focal adhesion;ko04550 Signaling pathways regulating pluripotency of stem cells;ko04611 Platelet activation;ko04620 Toll-like receptor signaling pathway;ko04650 Natural killer cell mediated cytotoxicity;ko04660 T cell receptor signaling pathway;ko04662 B cell receptor signaling pathway;ko04664 Fc epsilon RI signaling pathway;ko04666 Fc gamma R-mediated phagocytosis;ko04670 Leukocyte transendothelial migration;ko04062 Chemokine signaling pathway;ko04910 Insulin signaling pathway;ko04923 Regulation of lipolysis in adipocyte;ko04915 Estrogen signaling pathway;ko04914 Progesterone-mediated oocyte maturation;ko04917 Prolactin signaling pathway;ko04921 Oxytocin signaling pathway;ko04919 Thyroid hormone signaling pathway;ko04261 Adrenergic signaling in cardiomyocytes;ko04973 Carbohydrate digestion and absorption;ko04960 Aldosterone-regulated sodium reabsorption;ko04725 Cholinergic synapse;ko04722 Neurotrophin signaling pathway;ko04750 Inflammatory mediator regulation of TRP channels;ko04360 Axon guidance;ko04380 Osteoclast differentiation;ko04211 Longevity regulating pathway - mammal;ko04213 Longevity regulating pathway - multiple species;ko05200 Pathways in cancer;ko05230 Central carbon metabolism in cancer;ko05231 Choline metabolism in cancer;ko05205 Proteoglycans in cancer;ko05203 Viral carcinogenesis;ko05210 Colorectal cancer;ko05212 Pancreatic cancer;ko05214 Glioma;ko05221 Acute myeloid leukemia;ko05220 Chronic myeloid leukemia;ko05218 Melanoma;ko05211 Renal cell carcinoma;ko05215 Prostate cancer;ko05213 Endometrial cancer;ko05224 Breast cancer;ko05222 Small cell lung cancer;ko05223 Non-small cell lung cancer;ko04930 Type II diabetes mellitus;ko04932 Non-alcoholic fatty liver disease (NAFLD);ko04931 Insulin resistance;ko04933 AGE-RAGE signaling pathway in diabetic complications;ko05100 Bacterial invasion of epithelial cells;ko05166 HTLV-I infection;ko05162 Measles;ko05164 Influenza A;ko05161 Hepatitis B;ko05160 Hepatitis C;ko05169 Epstein-Barr virus infection;ko05146 Amoebiasis;ko05145 Toxoplasmosis;ko05142 Chagas disease (American trypanosomiasis);ko01521 EGFR tyrosine kinase inhibitor resistance;ko01522 Endocrine resistance;ko01524 Platinum drug resistance","KOG4637-Adaptor for phosphoinositide 3-kinase[T]"]
["LOC107049204",1.080846,5.771512,2.416788339,{"v":1.75e-39,"d":"1.75E-39"},{"v":6.99e-39,"d":"6.99E-39"},"up","LOC107049204","-","-","-","-"]
["SLC16A6",0.953339,5.083046,2.414632065,{"v":2.49e-57,"d":"2.49E-57"},{"v":1.21e-56,"d":"1.21E-56"},"up","SLC16A6","-","GO:0005887;GO:0008028;GO:0015718;GO:0016020;GO:0016021;GO:0055085","-","KOG2504-Monocarboxylate transporter[G]"]
["DDIT4",76.903931,406.558746,2.402334581,0,0,"up","DDIT4","-","GO:0001666;GO:0005622;GO:0005737;GO:0005739;GO:0005829;GO:0009968;GO:0032007;GO:0032984;GO:0042771;GO:0045820;GO:0051607;GO:0071549;GO:0071889;GO:0072593","K08270-ko04151 PI3K-Akt signaling pathway;ko04150 mTOR signaling pathway;ko05206 MicroRNAs in cancer","-"]
["SELENOP2",3.39972,17.947523,2.40029691,{"v":4.31e-94,"d":"4.31E-94"},{"v":2.78e-93,"d":"2.78E-93"},"up","SELENOP2","selenoprotein P2","-","-","-"]
["CROCC",1.860777,9.811638,2.398588837,{"v":6.45e-219,"d":"6.45E-219"},{"v":7.64e-218,"d":"7.64E-218"},"up","CROCC","-","-","-","-"]
["SLN",93.825912,494.418823,2.397675356,0,0,"up","SLN","sarcolipin","GO:0016020;GO:0016021;GO:0016529;GO:0030234;GO:0033017;GO:0070296;GO:0120162;GO:1901077;GO:1901894","-","-"]
["PCSK1",1.029102,5.414661,2.395485034,{"v":6.13e-101,"d":"6.13E-101"},{"v":4.13e-100,"d":"4.13E-100"},"up","PCSK1","-","GO:0004175;GO:0004252;GO:0005615;GO:0006508;GO:0008233;GO:0008236;GO:0016485;GO:0016486;GO:0016787;GO:0042802;GO:0043043","-","KOG3525-Subtilisin-like proprotein convertase[O]"]
["BATF3",1.600263,8.356655,2.384616548,{"v":4.36e-22,"d":"4.36E-22"},{"v":1.32e-21,"d":"1.32E-21"},"up","BATF3","-","GO:0000122;GO:0000978;GO:0003677;GO:0003700;GO:0005634;GO:0006355;GO:0006357;GO:0009615;GO:0043011;GO:0097028","-","-"]
["ACSL5",1.80216,9.406894,2.383991345,{"v":4.8e-88,"d":"4.80E-88"},{"v":2.97e-87,"d":"2.97E-87"},"up","ACSL5","acyl-CoA synthetase long-chain family member 5","GO:0003824;GO:0005634;GO:0005730;GO:0005739;GO:0008152;GO:0016020;GO:0016021","K01897-ko01212 Fatty acid metabolism;ko00061 Fatty acid biosynthesis;ko00071 Fatty acid degradation;ko04146 Peroxisome;ko02024 Quorum sensing;ko04920 Adipocytokine signaling pathway;ko03320 PPAR signaling pathway","KOG1256-Long-chain acyl-CoA synthetases (AMP-forming)[I]"]
["STK36",1.367923,7.061675,2.368023402,{"v":1.73e-117,"d":"1.73E-117"},{"v":1.3e-116,"d":"1.30E-116"},"up","STK36","-","GO:0003351;GO:0004672;GO:0005524;GO:0005634;GO:0005737;GO:0005829;GO:0006468;GO:0007228;GO:0007420;GO:0008134;GO:0009791;GO:0045880;GO:0051090;GO:0060271","-","-"]
["KNDC1",1.005751,5.187851,2.366863872,{"v":6.45e-135,"d":"6.45E-135"},{"v":5.34e-134,"d":"5.34E-134"},"up","KNDC1","-","GO:0005085;GO:0005088;GO:0005622;GO:0007264","-","KOG2378-cAMP-regulated guanine nucleotide exchange factor[T]"]
["CCDC92",2.135978,11.012144,2.366126688,{"v":9.53e-171,"d":"9.53E-171"},{"v":9.3e-170,"d":"9.30E-170"},"up","CCDC92","-","GO:0005654;GO:0005813;GO:0005814;GO:0043231","-","-"]
["VNN1",5.872244,30.238688,2.364411725,0,0,"up","VNN1","vanin 1","GO:0006807;GO:0015939;GO:0016811;GO:0017159","K08069-ko00770 Pantothenate and CoA biosynthesis","KOG0806-Carbon-nitrogen hydrolase[E]"]
["C3",5.063825,25.99749,2.360072888,0,0,"up","C3","complement component 3","GO:0001798;GO:0001934;GO:0001970;GO:0004866;GO:0005576;GO:0005615;GO:0006911;GO:0006954;GO:0006956;GO:0009617;GO:0010575;GO:0010828;GO:0010866;GO:0010884;GO:0010951;GO:0031715;GO:0032991;GO:0045745;GO:0045766;GO:0050766;GO:0060100;GO:0097242;GO:1905114;GO:2000427","K03990-ko04145 Phagosome;ko04610 Complement and coagulation cascades;ko05203 Viral carcinogenesis;ko05322 Systemic lupus erythematosus;ko05133 Pertussis;ko05134 Legionellosis;ko05150 Staphylococcus aureus infection;ko05152 Tuberculosis;ko05168 Herpes simplex infection;ko05140 Leishmaniasis;ko05142 Chagas disease (American trypanosomiasis)","KOG1366-Alpha-macroglobulin[O]"]
["FABP4",299.016998,1517.36731,2.343270958,0,0,"up","FABP4","fatty acid binding protein 4","GO:0001816;GO:0005324;GO:0005504;GO:0005634;GO:0005737;GO:0006469;GO:0008289;GO:0009617;GO:0015909;GO:0036041;GO:0042632;GO:0045892;GO:0050727;GO:0050729;GO:0050872;GO:0051427;GO:0071285;GO:0071356;GO:0120162","K08753-ko04923 Regulation of lipolysis in adipocyte;ko03320 PPAR signaling pathway","KOG4015-Fatty acid-binding protein FABP[I]"]
["STRIP2",1.461006,7.392771,2.339153122,{"v":7.74e-95,"d":"7.74E-95"},{"v":5.02e-94,"d":"5.02E-94"},"up","STRIP2","-","GO:0005737;GO:0005829;GO:0007010;GO:0008360;GO:0016477","-","KOG3680-Uncharacterized conserved protein[S]"]
["LOC107054976",3.699602,18.664574,2.334860601,{"v":3.38e-27,"d":"3.38E-27"},{"v":1.12e-26,"d":"1.12E-26"},"up","LOC107054976","-","-","-","-"]
["THBS1",24.722183,124.479103,2.332025524,0,0,"up","THBS1","thrombospondin 1","GO:0000187;GO:0001786;GO:0001937;GO:0001953;GO:0001968;GO:0002040;GO:0002544;GO:0002581;GO:0002605;GO:0005178;GO:0005509;GO:0005576;GO:0005577;GO:0005615;GO:0006954;GO:0006955;GO:0007050;GO:0007155;GO:0008201;GO:0008284;GO:0009749;GO:0009897;GO:0009986;GO:0010595;GO:0010596;GO:0010748;GO:0010751;GO:0010754;GO:0010757;GO:0010763;GO:0016477;GO:0016525;GO:0017134;GO:0018149;GO:0030141;GO:0030169;GO:0030194;GO:0030335;GO:0030511;GO:0031012;GO:0031091;GO:0032026;GO:0032695;GO:0040037;GO:0042327;GO:0042493;GO:0042535;GO:0043032;GO:0043066;GO:0043154;GO:0043236;GO:0043536;GO:0043537;GO:0043652;GO:0045727;GO:0045766;GO:0048661;GO:0050840;GO:0050921;GO:0051592;GO:0051897;GO:0051918;GO:0070051;GO:0070052;GO:0090051;GO:1902043;GO:1903588;GO:1903671;GO:2000353;GO:2000379;GO:2001027","K16857-ko04015 Rap1 signaling pathway;ko04350 TGF-beta signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04512 ECM-receptor interaction;ko04145 Phagosome;ko04115 p53 signaling pathway;ko04510 Focal adhesion;ko05206 MicroRNAs in cancer;ko05205 Proteoglycans in cancer;ko05219 Bladder cancer;ko05144 Malaria","KOG1480-Netrin transmembrane receptor unc-5[T]"]
["PLPP7",3.280319,16.437658,2.325096738,{"v":4.47e-81,"d":"4.47E-81"},{"v":2.63e-80,"d":"2.63E-80"},"up","PLPP7","-","GO:0005635;GO:0010832;GO:0016020;GO:0016021","-","KOG4268-Uncharacterized conserved protein containing PAP2 domain[S]"]
["DNAJB4",8.306118,41.618591,2.324981851,0,0,"up","DNAJB4","-","GO:0001671;GO:0005654;GO:0005829;GO:0005886;GO:0006457;GO:0032781;GO:0051082;GO:0051087","-","KOG0714-Molecular chaperone (DnaJ superfamily)[O]"]
["LSMEM1",6.732494,33.705814,2.323784523,{"v":1.13e-120,"d":"1.13E-120"},{"v":8.59e-120,"d":"8.59E-120"},"up","LSMEM1","-","GO:0005829;GO:0016020;GO:0016021","-","-"]
["FABP5",90.581581,451.192749,2.316454257,0,0,"up","FABP5","fatty acid binding protein 5","GO:0001972;GO:0005504;GO:0005615;GO:0005634;GO:0005737;GO:0006006;GO:0006629;GO:0006656;GO:0008289;GO:0010829;GO:0014069;GO:0031392;GO:0035360;GO:0042593;GO:0042802;GO:0045202;GO:0051930;GO:0099178;GO:0120162","K08754-ko03320 PPAR signaling pathway","KOG4015-Fatty acid-binding protein FABP[I]"]
["PHKG1",68.298225,340.107941,2.316072701,0,0,"up","PHKG1","phosphorylase kinase catalytic subunit gamma 1","GO:0000166;GO:0004672;GO:0004674;GO:0004689;GO:0005516;GO:0005524;GO:0005964;GO:0005977;GO:0005978;GO:0006468;GO:0018105;GO:0018107;GO:0035556","K00871-ko04020 Calcium signaling pathway;ko04910 Insulin signaling pathway;ko04922 Glucagon signaling pathway","KOG0599-Phosphorylase kinase gamma subunit[G]"]
["LOC112533368",4.777449,23.691626,2.310064839,{"v":6.17e-51,"d":"6.17E-51"},{"v":2.8e-50,"d":"2.80E-50"},"up","LOC112533368","-","-","-","-"]
["PABPC4",15.234122,75.524025,2.3096293,0,0,"up","PABPC4","-","GO:0003676;GO:0003723;GO:0005737","K13126-ko03013 RNA transport;ko03015 mRNA surveillance pathway;ko03018 RNA degradation","KOG0123-Polyadenylate-binding protein (RRM superfamily)[AJ]"]
["FAM180A",2.465362,12.215416,2.308831591,{"v":2.26e-80,"d":"2.26E-80"},{"v":1.32e-79,"d":"1.32E-79"},"up","FAM180A","-","-","-","-"]
["FAM189A2",1.764777,8.721946,2.305164165,{"v":7.44e-76,"d":"7.44E-76"},{"v":4.2e-75,"d":"4.20E-75"},"up","FAM189A2","-","GO:0016020;GO:0016021","-","-"]
["PNPLA2",60.24432,297.014221,2.301634877,0,0,"up","PNPLA2","patatin like phospholipase domain containing 2","GO:0004806;GO:0005654;GO:0005811;GO:0005829;GO:0006629;GO:0008152;GO:0010891;GO:0010898;GO:0016042;GO:0016787;GO:0019433;GO:0019915;GO:0034389;GO:0044242","K16816-ko00561 Glycerolipid metabolism;ko04923 Regulation of lipolysis in adipocyte","KOG3773-Adiponutrin and related vesicular transport proteins; predicted alpha/beta hydrolase[U]"]
["GSTA4L",76.715385,377.661316,2.299505176,0,0,"up","GSTA4L","glutathione S-transferase alpha 4-like","GO:0004364;GO:0006749;GO:0006805;GO:0008152;GO:0016740;GO:0042802;GO:0042803","K00799-ko00480 Glutathione metabolism;ko00980 Metabolism of xenobiotics by cytochrome P450;ko00982 Drug metabolism - cytochrome P450;ko05204 Chemical carcinogenesis;ko01524 Platinum drug resistance","KOG1695-Glutathione S-transferase[O]"]
["KCNK4",13.398098,65.564445,2.290885457,{"v":2.23e-299,"d":"2.23E-299"},{"v":3.38e-298,"d":"3.38E-298"},"up","KCNK4","-","GO:0005267;GO:0005887;GO:0006811;GO:0016020;GO:0016021;GO:0022841;GO:0030322;GO:0071805","-","-"]
["FAM134B",54.691517,267.219147,2.2886344,0,0,"up","FAM134B","-","GO:0005730;GO:0005783;GO:0005801;GO:0016020;GO:0016021;GO:0016604;GO:0019233;GO:0030176;GO:0043524;GO:0061709","-","-"]
["HIST1H46L2",14.605364,71.332657,2.288064398,{"v":5.32e-95,"d":"5.32E-95"},{"v":3.45e-94,"d":"3.45E-94"},"up","HIST1H46L2","histone cluster 1, H4-IV, germinal H4-like 2","-","-","KOG3467-Histone H4[B]"]
["CHST11",9.16804,44.7593,2.28750223,0,0,"up","CHST11","-","-","K01017-ko00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate","KOG4651-Chondroitin 6-sulfotransferase and related sulfotransferases[MW]"]
["ABCB6",5.708665,27.856976,2.286813347,{"v":1.46e-231,"d":"1.46E-231"},{"v":1.8e-230,"d":"1.80E-230"},"up","ABCB6","-","GO:0000166;GO:0005524;GO:0005654;GO:0005739;GO:0005740;GO:0005741;GO:0005768;GO:0005783;GO:0005794;GO:0005829;GO:0005886;GO:0006779;GO:0007420;GO:0015439;GO:0015562;GO:0015886;GO:0016020;GO:0016021;GO:0016887;GO:0020037;GO:0031307;GO:0042626;GO:0043588;GO:0055085","K05661-ko02010 ABC transporters","KOG0056-Heavy metal exporter HMT1, ABC superfamily[P]"]
["NFATC1",6.979466,34.034729,2.285819057,0,0,"up","NFATC1","-","GO:0000790;GO:0003677;GO:0003700;GO:0005634;GO:0005654;GO:0006355;GO:0016604;GO:0030178;GO:0033173;GO:0035556;GO:0045893;GO:0045944;GO:0048699;GO:1905064","K04446-ko04010 MAPK signaling pathway;ko04310 Wnt signaling pathway;ko04024 cAMP signaling pathway;ko04022 cGMP - PKG signaling pathway;ko04650 Natural killer cell mediated cytotoxicity;ko04660 T cell receptor signaling pathway;ko04662 B cell receptor signaling pathway;ko04921 Oxytocin signaling pathway;ko04380 Osteoclast differentiation;ko05321 Inflammatiory bowel disease (IBD);ko04933 AGE-RAGE signaling pathway in diabetic complications;ko05166 HTLV-I infection;ko05161 Hepatitis B","-"]
["COQ10A",6.487718,31.603445,2.284298814,{"v":1e-181,"d":"1.00E-181"},{"v":1.02e-180,"d":"1.02E-180"},"up","COQ10A","-","-","-","KOG3177-Oligoketide cyclase/lipid transport protein[I]"]
["RPTC15L",2.259146,10.910968,2.271929686,{"v":3.2e-151,"d":"3.20E-151"},{"v":2.85e-150,"d":"2.85E-150"},"up","RPTC15L","-","-","-","-"]
["CILP",9.28209,44.685585,2.26728792,0,0,"up","CILP","-","GO:0005615;GO:0010629;GO:0043569;GO:0060392;GO:0062023;GO:0071560","-","-"]
["MUSK",1.182397,5.678613,2.263824081,{"v":2.49e-49,"d":"2.49E-49"},{"v":1.11e-48,"d":"1.11E-48"},"up","MUSK","muscle associated receptor tyrosine kinase","GO:0000166;GO:0001934;GO:0004672;GO:0004713;GO:0004714;GO:0005524;GO:0005886;GO:0006468;GO:0007275;GO:0007528;GO:0008582;GO:0016020;GO:0016021;GO:0016301;GO:0016310;GO:0016740;GO:0018108;GO:0030054;GO:0030154;GO:0043235;GO:0045202;GO:0045211","-","KOG1026-Nerve growth factor receptor TRKA and related tyrosine kinases[TU]"]
["LANCL3",1.409068,6.76554,2.263463853,{"v":1.57e-161,"d":"1.57E-161"},{"v":1.48e-160,"d":"1.48E-160"},"up","LANCL3","-","GO:0003824;GO:0005886;GO:0007165","-","KOG2787-Lanthionine synthetase C-like protein 1[V]"]
["LTBP2",2.348479,11.226243,2.257076595,0,0,"up","LTBP2","-","GO:0005509;GO:0097435","-","KOG1217-Fibrillins and related proteins containing Ca2+-binding EGF-like domains[T]"]
["HSD17B11L",2.414891,11.536238,2.256142856,{"v":4.93e-56,"d":"4.93E-56"},{"v":2.37e-55,"d":"2.37E-55"},"up","HSD17B11L","-","-","-","-"]
["CORO6",40.17543,191.597214,2.253691213,0,0,"up","CORO6","-","GO:0015629;GO:0030036;GO:0051015","-","KOG0303-Actin-binding protein Coronin, contains WD40 repeats[Z]"]
["PLIN5",2.159008,10.292216,2.253113146,{"v":3.83e-52,"d":"3.83E-52"},{"v":1.76e-51,"d":"1.76E-51"},"up","PLIN5","-","-","-","-"]
["CLCN1",1.187934,5.66032,2.252428932,{"v":9.17e-222,"d":"9.17E-222"},{"v":1.1e-220,"d":"1.10E-220"},"up","CLCN1","-","GO:0005247;GO:0005887;GO:0006811;GO:0006821;GO:0006936;GO:0016020;GO:0016021;GO:0019227;GO:0042383;GO:0042803;GO:0055085;GO:1902476","-","KOG0476-Cl- channel CLC-2 and related proteins (CLC superfamily)[P]"]
["TRIM2",1.548685,7.338026,2.244348284,{"v":1.31e-56,"d":"1.31E-56"},{"v":6.34e-56,"d":"6.34E-56"},"up","TRIM2","tripartite motif containing 2","GO:0005622;GO:0005737;GO:0008270;GO:0046872","-","KOG2177-Predicted E3 ubiquitin ligase[O]"]
["ATG9B",10.491885,49.65049,2.242534056,0,0,"up","ATG9B","-","GO:0000045;GO:0005737;GO:0005776;GO:0005794;GO:0006914;GO:0015031;GO:0016020;GO:0016021;GO:0030659;GO:0031410","-","KOG2173-Integral membrane protein[R]"]
["KCNRG",2.751954,12.956596,2.235158478,{"v":5.64e-44,"d":"5.64E-44"},{"v":2.39e-43,"d":"2.39E-43"},"up","KCNRG","-","GO:0005783;GO:0042802;GO:0051260;GO:1902260","-","KOG2723-Uncharacterized conserved protein, contains BTB/POZ domain[R]"]
["CXXC5",2.791847,13.135512,2.23418065,{"v":6.28e-83,"d":"6.28E-83"},{"v":3.74e-82,"d":"3.74E-82"},"up","CXXC5","-","GO:0000122;GO:0003677;GO:0005654;GO:0005829;GO:0008134;GO:0008270;GO:0043565","-","-"]
["ERMN",3.290621,15.427691,2.229090378,{"v":1.56e-83,"d":"1.56E-83"},{"v":9.36e-83,"d":"9.36E-83"},"up","ERMN","-","GO:0001763;GO:0003779;GO:0005737;GO:0005938;GO:0007015;GO:0008360;GO:0030175;GO:0031344;GO:0033269;GO:0033270;GO:0043025;GO:0043209;GO:0051015","-","-"]
["LVRN",10.588578,49.387962,2.221650582,0,0,"up","LVRN","-","GO:0004177;GO:0005737;GO:0005886;GO:0006508;GO:0007165;GO:0007267;GO:0008217;GO:0008233;GO:0008237;GO:0008270;GO:0016787;GO:0042277;GO:0043171;GO:0046872;GO:0070006","-","KOG1046-Puromycin-sensitive aminopeptidase and related aminopeptidases[EO]"]
["NRN1",27.138428,126.174927,2.217016192,0,0,"up","NRN1","neuritin 1","GO:0005615;GO:0007399;GO:0032281;GO:0042803;GO:0046658;GO:0046982;GO:0098978;GO:1990138;GO:2000300","-","-"]
["OTX1",3.11999,14.478323,2.214281197,{"v":7.83e-80,"d":"7.83E-80"},{"v":4.56e-79,"d":"4.56E-79"},"up","OTX1","-","GO:0000978;GO:0003677;GO:0003700;GO:0005634;GO:0006355;GO:0006357;GO:0006366;GO:0007275;GO:0009952;GO:0022037;GO:0030900;GO:0030901;GO:0042472;GO:0043565;GO:0045944;GO:0048852","-","KOG2251-Homeobox transcription factor[K]"]
["TNFAIP6",2.318023,10.702008,2.206914726,{"v":2.04e-54,"d":"2.04E-54"},{"v":9.59e-54,"d":"9.59E-54"},"up","TNFAIP6","TNF alpha induced protein 6","-","-","KOG4586-CUB domain-containing protein[R]"]
["THRB",2.139017,9.874058,2.206695171,{"v":1.94e-199,"d":"1.94E-199"},{"v":2.12e-198,"d":"2.12E-198"},"up","THRB","thyroid hormone receptor beta","GO:0003677;GO:0003700;GO:0003707;GO:0005515;GO:0005634;GO:0006351;GO:0006355;GO:0008270;GO:0030522;GO:0043401;GO:0043565;GO:0046872;GO:0070324;GO:1990837;GO:0000122;GO:0000790;GO:0003677;GO:0003700;GO:0003707;GO:0005634;GO:0006351;GO:0006355;GO:0006357;GO:0007605;GO:0007621;GO:0008016;GO:0008050;GO:0008270;GO:0009887;GO:0016020;GO:0016021;GO:0016604;GO:0019899;GO:0030522;GO:0031490;GO:0042480;GO:0043401;GO:0043565;GO:0045892;GO:0045944;GO:0046549;GO:0046872;GO:0060509;GO:0070324;GO:0097474;GO:1990837","K08362-ko04080 Neuroactive ligand-receptor interaction;ko04919 Thyroid hormone signaling pathway","KOG4217-Nuclear receptors of the nerve growth factor-induced protein B type[K]"]
["IFT46",19.493868,89.094666,2.192318681,0,0,"up","IFT46","-","GO:0005813;GO:0005929;GO:0007224;GO:0030992;GO:0031514;GO:0042073;GO:0060271","-","-"]
["WDR86",4.091538,18.681519,2.19089661,{"v":4.59e-112,"d":"4.59E-112"},{"v":3.33e-111,"d":"3.33E-111"},"up","WDR86","-","-","-","KOG0274-Cdc4 and related F-box and WD-40 proteins[R]"]
["RFX2",5.737772,26.068771,2.183760023,0,0,"up","RFX2","-","GO:0000977;GO:0000978;GO:0001675;GO:0003677;GO:0003700;GO:0005634;GO:0006355;GO:0006357;GO:0007286;GO:0045944;GO:0060271;GO:1990830","-","KOG3712-RFX family transcription factor[K]"]
["G0S2",10.705522,48.499825,2.179624399,{"v":5.96e-98,"d":"5.96E-98"},{"v":3.95e-97,"d":"3.95E-97"},"up","G0S2","G0/G1 switch 2","-","-","-"]
["SRRL",8.864186,40.143475,2.179105449,{"v":7.1e-284,"d":"7.10E-284"},{"v":1.02e-282,"d":"1.02E-282"},"up","SRRL","-","GO:0016020;GO:0016021","K01754-ko01200 Carbon metabolism;ko01230 Biosynthesis of amino acids;ko00260 Glycine, serine and threonine metabolism;ko00290 Valine, leucine and isoleucine biosynthesis","-"]
["SGCD",8.482696,38.399086,2.178477206,0,0,"up","SGCD","-","GO:0007517;GO:0016010;GO:0016011;GO:0016012;GO:0016020;GO:0016021;GO:0042383;GO:0048738;GO:0055001;GO:0060047;GO:0061024","-","KOG3950-Gamma/delta sarcoglycan[Z]"]
["FAM195A",48.96209,221.06012,2.174701734,0,0,"up","FAM195A","-","-","-","-"]
["TRABD2B",1.178405,5.31704,2.173787863,{"v":8.99e-262,"d":"8.99E-262"},{"v":1.22e-260,"d":"1.22E-260"},"up","TRABD2B","-","GO:0004222;GO:0005887;GO:0006508;GO:0017147;GO:0030178;GO:0031301;GO:0032461;GO:1904808","-","-"]
["GSTT1",44.586258,199.874832,2.164425793,0,0,"up","GSTT1","glutathione S-transferase theta 1","GO:0004364;GO:0005737;GO:0006749;GO:0016740","K00799-ko00480 Glutathione metabolism;ko00980 Metabolism of xenobiotics by cytochrome P450;ko00982 Drug metabolism - cytochrome P450;ko05204 Chemical carcinogenesis;ko01524 Platinum drug resistance","KOG0867-Glutathione S-transferase[O]"]
["SLC23A2",2.874425,12.880816,2.163878698,{"v":3.31e-77,"d":"3.31E-77"},{"v":1.88e-76,"d":"1.88E-76"},"up","SLC23A2","solute carrier family 23 member 2","-","-","KOG1292-Xanthine/uracil transporters[F]"]
["LOC112530130",2.877725,12.883679,2.162543984,0,0,"up","LOC112530130","-","-","-","-"]
["ZFAND5",54.536781,243.753143,2.160119368,0,0,"up","ZFAND5","zinc finger AN1-type containing 5","GO:0001944;GO:0003016;GO:0003677;GO:0008270;GO:0010761;GO:0046872;GO:0048008;GO:0048705;GO:0048745;GO:0060324","-","KOG3173-Predicted Zn-finger protein[R]"]
["FRMPD3",1.293012,5.776636,2.159493925,{"v":2.94e-118,"d":"2.94E-118"},{"v":2.21e-117,"d":"2.21E-117"},"up","FRMPD3","-","-","-","-"]
["MIR6578",18.658958,83.191666,2.156570587,{"v":1.17e-15,"d":"1.17E-15"},{"v":3.06e-15,"d":"3.06E-15"},"up","MIR6578","microRNA 6578","-","-","-"]
["SOX5",1.339782,5.970841,2.155935877,{"v":1.66e-112,"d":"1.66E-112"},{"v":1.21e-111,"d":"1.21E-111"},"up","SOX5","SRY-box 5","GO:0003677;GO:0005634;GO:0032332;GO:0055059;GO:0061036;GO:0071560;GO:2000741","-","KOG0528-HMG-box transcription factor SOX5[K]"]
["LOC107049808",1.498843,6.655552,2.150709053,{"v":1.02e-06,"d":"1.02E-06"},{"v":1.92e-06,"d":"1.92E-06"},"up","LOC107049808","-","-","-","-"]
["APOA1",994.734009,4416.34375,2.150469763,0,0,"up","APOA1","apolipoprotein A1","GO:0001540;GO:0001932;GO:0001935;GO:0002740;GO:0005319;GO:0005515;GO:0005543;GO:0005576;GO:0005615;GO:0006629;GO:0006644;GO:0006656;GO:0006695;GO:0006869;GO:0007186;GO:0007229;GO:0008035;GO:0008202;GO:0008203;GO:0008211;GO:0008289;GO:0010804;GO:0010873;GO:0010898;GO:0010903;GO:0015485;GO:0017127;GO:0018158;GO:0018206;GO:0019433;GO:0019899;GO:0019915;GO:0030139;GO:0030300;GO:0030301;GO:0030325;GO:0031072;GO:0031102;GO:0031210;GO:0031410;GO:0032489;GO:0033344;GO:0033700;GO:0034115;GO:0034190;GO:0034191;GO:0034361;GO:0034364;GO:0034366;GO:0034372;GO:0034375;GO:0034380;GO:0035025;GO:0042157;GO:0042158;GO:0042627;GO:0042632;GO:0042802;GO:0043534;GO:0043691;GO:0045445;GO:0045499;GO:0045723;GO:0046470;GO:0050713;GO:0050728;GO:0050821;GO:0050919;GO:0051006;GO:0051180;GO:0051345;GO:0051346;GO:0051496;GO:0051726;GO:0055091;GO:0060228;GO:0060354;GO:0060761;GO:0070328;GO:0070508;GO:0070653;GO:0071813;GO:0072562;GO:1900026;GO:1901247","K08757-ko03320 PPAR signaling pathway;ko04975 Fat digestion and absorption;ko04977 Vitamin digestion and absorption;ko05143 African trypanosomiasis","-"]
["SLC43A3",7.521457,33.390568,2.150356573,{"v":1.9e-196,"d":"1.90E-196"},{"v":2.04e-195,"d":"2.04E-195"},"up","SLC43A3","-","GO:0016020;GO:0016021;GO:0055085","-","-"]
["ZDHHC1",2.393489,10.612734,2.148609283,{"v":2.31e-107,"d":"2.31E-107"},{"v":1.62e-106,"d":"1.62E-106"},"up","ZDHHC1","-","GO:0005783;GO:0016020;GO:0016021;GO:0016409;GO:0016740;GO:0016746;GO:0018345;GO:0019706","-","-"]
["PRPS2",2.038856,9.015845,2.144702828,{"v":9.3e-61,"d":"9.30E-61"},{"v":4.64e-60,"d":"4.64E-60"},"up","PRPS2","phosphoribosyl pyrophosphate synthetase 2","GO:0000287;GO:0004749;GO:0009116;GO:0009156;GO:0009165;GO:0044249;GO:0000166;GO:0000287;GO:0004749;GO:0005524;GO:0006015;GO:0009116;GO:0009156;GO:0009165;GO:0016301;GO:0016310;GO:0016740;GO:0042802;GO:0042803;GO:0044249;GO:0046872","K00948-ko01200 Carbon metabolism;ko01230 Biosynthesis of amino acids;ko00030 Pentose phosphate pathway;ko00230 Purine metabolism","KOG1448-Ribose-phosphate pyrophosphokinase[FE]"]
["LOC770936",5.101786,22.531748,2.142884951,{"v":3.93e-258,"d":"3.93E-258"},{"v":5.31e-257,"d":"5.31E-257"},"up","LOC770936","-","-","-","-"]
["MYO1A",1.409769,6.220338,2.141534189,{"v":7.33e-62,"d":"7.33E-62"},{"v":3.7e-61,"d":"3.70E-61"},"up","MYO1A","myosin IA","GO:0000166;GO:0003774;GO:0003779;GO:0005524;GO:0005737;GO:0005902;GO:0005903;GO:0007605;GO:0009925;GO:0016323;GO:0016324;GO:0016328;GO:0016459;GO:0030030;GO:0030033;GO:0030864;GO:0031941;GO:0044853;GO:0051015;GO:0051648;GO:0000146;GO:0000166;GO:0003774;GO:0003779;GO:0005516;GO:0005524;GO:0005737;GO:0005884;GO:0005902;GO:0016197;GO:0016328;GO:0016459;GO:0016887;GO:0030027;GO:0030048;GO:0045056","-","KOG0164-Myosin class I heavy chain[Z]"]
["COL16A1",25.227819,111.234657,2.140518961,0,0,"up","COL16A1","-","-","-","-"]
["PHOSPHO1",10.374829,45.686165,2.138669787,{"v":4.56e-285,"d":"4.56E-285"},{"v":6.6e-284,"d":"6.60E-284"},"up","PHOSPHO1","phosphoethanolamine/phosphocholine phosphatase","GO:0001958;GO:0016311;GO:0016462;GO:0016787;GO:0016791;GO:0030500;GO:0031012;GO:0035630;GO:0046872;GO:0052731;GO:0052732;GO:0065010","K06124-ko00564 Glycerophospholipid metabolism","KOG3120-Predicted haloacid dehalogenase-like hydrolase[R]"]
["TRAF3IP1",9.892808,43.427689,2.134163199,{"v":5.52e-272,"d":"5.52E-272"},{"v":7.71e-271,"d":"7.71E-271"},"up","TRAF3IP1","-","GO:0001738;GO:0001822;GO:0001933;GO:0005813;GO:0005929;GO:0005930;GO:0008017;GO:0021532;GO:0030992;GO:0031076;GO:0031333;GO:0032480;GO:0032688;GO:0035050;GO:0035869;GO:0036064;GO:0036342;GO:0042073;GO:0042733;GO:0050687;GO:0060271;GO:0070507;GO:0097542;GO:0097546;GO:1901621","-","KOG3809-Microtubule-binding protein MIP-T3[Z]"]
["LCA5L",1.924399,8.443369,2.133410811,{"v":7.51e-116,"d":"7.51E-116"},{"v":5.58e-115,"d":"5.58E-115"},"up","LCA5L","-","-","-","-"]
["HSPB2",7.706379,33.762375,2.131291349,{"v":5.37e-77,"d":"5.37E-77"},{"v":3.05e-76,"d":"3.05E-76"},"up","HSPB2","heat shock protein family B (small) member 2","GO:0005212;GO:0007525","-","KOG3591-Alpha crystallins[O]"]
["NPTX1",5.827868,25.420874,2.124973527,{"v":4.66e-105,"d":"4.66E-105"},{"v":3.22e-104,"d":"3.22E-104"},"up","NPTX1","-","GO:0060385;GO:0098962;GO:0098978","-","-"]
["LOC101749934",4.886052,21.158476,2.114494594,{"v":1.41e-136,"d":"1.41E-136"},{"v":1.18e-135,"d":"1.18E-135"},"up","LOC101749934","-","-","-","-"]
["CDO1",26.221838,113.526016,2.114182229,0,0,"up","CDO1","-","GO:0005506;GO:0005829;GO:0016702;GO:0046872;GO:0055114","K00456-ko00270 Cysteine and methionine metabolism;ko00430 Taurine and hypotaurine metabolism","KOG4064-Cysteine dioxygenase CDO1[E]"]
["PACRGL",2.12063,9.160193,2.110885069,{"v":8.14e-49,"d":"8.14E-49"},{"v":3.62e-48,"d":"3.62E-48"},"up","PACRGL","-","-","-","KOG3961-Uncharacterized conserved protein[S]"]
["CYP27A1",7.381342,31.879629,2.110679799,{"v":6.26e-198,"d":"6.26E-198"},{"v":6.77e-197,"d":"6.77E-197"},"up","CYP27A1","-","GO:0004497;GO:0005506;GO:0005739;GO:0016491;GO:0016705;GO:0020037;GO:0046872;GO:0055114","K00488-ko00120 Primary bile acid biosynthesis;ko03320 PPAR signaling pathway","-"]
["TCERG1L",1.239722,5.312055,2.099253443,{"v":7.42e-44,"d":"7.42E-44"},{"v":3.14e-43,"d":"3.14E-43"},"up","TCERG1L","-","-","-","KOG0155-Transcription factor CA150[K]"]
["DPCD",12.929691,55.308777,2.096820644,{"v":2.74e-113,"d":"2.74E-113"},{"v":2e-112,"d":"2.00E-112"},"up","DPCD","deleted in primary ciliary dyskinesia homolog (mouse)","GO:0003351;GO:0007283;GO:0007368;GO:0021591;GO:0021670;GO:0021678;GO:0030317;GO:0060972","-","-"]
["TTC26",4.712334,20.135582,2.09523347,{"v":2.19e-151,"d":"2.19E-151"},{"v":1.96e-150,"d":"1.96E-150"},"up","TTC26","-","GO:0005813;GO:0005929;GO:0007224;GO:0007286;GO:0030992;GO:0036064;GO:0042073;GO:0060271;GO:0120170;GO:1905198","-","KOG3785-Uncharacterized conserved protein[S]"]
["TEAD4",22.873734,97.622536,2.093522334,0,0,"up","TEAD4","TEA domain transcription factor 4","GO:0003677;GO:0003700;GO:0005634;GO:0005654;GO:0006351;GO:0006355;GO:0035329;GO:0001085;GO:0003677;GO:0003700;GO:0005634;GO:0005667;GO:0006351;GO:0006355;GO:0035329;GO:0043565;GO:0044212;GO:0045944;GO:0048568","-","KOG3841-TEF-1 and related transcription factor, TEAD family[K]"]
["LOC107054141",1.841509,7.858787,2.093418202,{"v":1.25e-54,"d":"1.25E-54"},{"v":5.91e-54,"d":"5.91E-54"},"up","LOC107054141","-","-","-","-"]
["C1H2ORF40",58.080441,247.327393,2.090297723,0,0,"up","C1H2ORF40","-","GO:0005615;GO:0005737;GO:0007417;GO:0008285;GO:0009611;GO:0016324;GO:0031145;GO:0070314;GO:0090398","-","-"]
["SOUL",1.410665,5.992765,2.086846379,{"v":3.03e-55,"d":"3.03E-55"},{"v":1.44e-54,"d":"1.44E-54"},"up","SOUL","SOUL protein","-","-","-"]
["SNX21",6.650546,28.196146,2.083953287,{"v":1.35e-149,"d":"1.35E-149"},{"v":1.19e-148,"d":"1.19E-148"},"up","SNX21","-","GO:0005546;GO:0031901;GO:0032266;GO:0035091","-","-"]
["LOC101748650",2.105077,8.924524,2.083902218,{"v":1.62e-19,"d":"1.62E-19"},{"v":4.66e-19,"d":"4.66E-19"},"up","LOC101748650","-","-","-","-"]
["WWP2",16.556459,70.072769,2.081459756,0,0,"up","WWP2","WW domain containing E3 ubiquitin protein ligase 2","GO:0000122;GO:0001085;GO:0001190;GO:0004842;GO:0005576;GO:0005634;GO:0005737;GO:0006366;GO:0006511;GO:0006858;GO:0008134;GO:0010629;GO:0016567;GO:0016740;GO:0032410;GO:0034765;GO:0042391;GO:0043161;GO:0043433;GO:0045892;GO:0045944;GO:0051224;GO:0051865;GO:0061630;GO:0070534;GO:1901016","K05630-ko04120 Ubiquitin mediated proteolysis","KOG0940-Ubiquitin protein ligase RSP5/NEDD4[O]"]
["SLC16A10",6.835206,28.792585,2.074640596,{"v":7.45e-145,"d":"7.45E-145"},{"v":6.48e-144,"d":"6.48E-144"},"up","SLC16A10","solute carrier family 16 member 10","GO:0005887;GO:0008028;GO:0015173;GO:0015349;GO:0015718;GO:0015801;GO:0016020;GO:0016021;GO:0055085;GO:0070327","-","KOG2504-Monocarboxylate transporter[G]"]
["SESN1",104.395531,439.662659,2.074337054,0,0,"up","SESN1","-","GO:0001650;GO:0003674;GO:0005575;GO:0005634;GO:0005737;GO:0008150;GO:0034198;GO:0042149;GO:0061700;GO:0070728;GO:0072593;GO:0098869;GO:1901031;GO:1904262","K10141-ko04115 p53 signaling pathway;ko04211 Longevity regulating pathway - mammal","KOG3746-Uncharacterized conserved protein[S]"]
["SYNPO",10.242791,43.096012,2.072945491,0,0,"up","SYNPO","-","GO:0003779;GO:0005634;GO:0008542;GO:0015629;GO:0030018;GO:0032233;GO:0048169;GO:0097444;GO:0098685;GO:0098978;GO:0099170;GO:0099588;GO:1905355","-","-"]
["TTLL1",1.268912,5.334549,2.071774285,{"v":5.51e-117,"d":"5.51E-117"},{"v":4.12e-116,"d":"4.12E-116"},"up","TTLL1","-","GO:0003351;GO:0005524;GO:0006464;GO:0007288;GO:0018095;GO:0035082;GO:1905419","-","KOG2157-Predicted tubulin-tyrosine ligase[O]"]
["TMCC2",12.56225,52.71389,2.069088273,0,0,"up","TMCC2","-","GO:0005783;GO:0016020;GO:0016021;GO:0042982","-","KOG3850-Predicted membrane protein[S]"]
["ATP2C2",9.105986,38.167103,2.067442539,0,0,"up","ATP2C2","-","GO:0000166;GO:0005388;GO:0005524;GO:0006811;GO:0006816;GO:0009898;GO:0016020;GO:0016021;GO:0016787;GO:0031410;GO:0048471;GO:0070588;GO:0072659;GO:0090280;GO:0099132","-","-"]
["RBM24",39.883183,166.939468,2.06547262,0,0,"up","RBM24","RNA binding motif protein 24","GO:0000381;GO:0003197;GO:0003676;GO:0003723;GO:0003730;GO:0005654;GO:0005737;GO:0005829;GO:0006974;GO:0010830;GO:0010831;GO:0035925;GO:0043488;GO:0048255;GO:0061157;GO:0061158;GO:0097157;GO:1902811;GO:1905870;GO:1990715;GO:1990825;GO:2000738;GO:2000766;GO:0000381;GO:0003676;GO:0003723;GO:0003730;GO:0005634;GO:0005737;GO:0006397;GO:0006417;GO:0006974;GO:0008380;GO:0010830;GO:0010831;GO:0030154;GO:0035925;GO:0043488;GO:0045663;GO:0048255;GO:0061157;GO:0061158;GO:0097157;GO:1902811;GO:1905870;GO:1990715;GO:1990825;GO:2000738;GO:2000766","-","KOG0149-Predicted RNA-binding protein SEB4 (RRM superfamily)[R]"]
["FMOD",63.320492,264.609955,2.063122968,0,0,"up","FMOD","fibromodulin","GO:0005576;GO:0005615;GO:0007409;GO:0030199;GO:0062023","-","KOG4194-Membrane glycoprotein LIG-1[T]"]
["SH2B2",5.477301,22.879152,2.062496511,{"v":1.55e-251,"d":"1.55E-251"},{"v":2.04e-250,"d":"2.04E-250"},"up","SH2B2","-","GO:0001725;GO:0001726;GO:0001922;GO:0005068;GO:0005070;GO:0005737;GO:0005884;GO:0005886;GO:0007165;GO:0008269;GO:0008286;GO:0009967;GO:0019221;GO:0019222;GO:0030036;GO:0035556;GO:0035591;GO:0046425;GO:0050776;GO:0050851","K07193-ko04910 Insulin signaling pathway;ko04722 Neurotrophin signaling pathway","-"]
["LAMP5",3.595136,15.009999,2.061805628,{"v":1.43e-82,"d":"1.43E-82"},{"v":8.52e-82,"d":"8.52E-82"},"up","LAMP5","-","GO:0005886;GO:0010008;GO:0016020;GO:0016021;GO:0030659;GO:0031901;GO:0032584;GO:0032590;GO:0033116;GO:0055038","-","KOG4818-Lysosomal-associated membrane protein[R]"]
["EFHD2",1.242217,5.171802,2.057749827,{"v":4.4e-17,"d":"4.40E-17"},{"v":1.2e-16,"d":"1.20E-16"},"up","EFHD2","-","GO:0005509","-","KOG0041-Predicted Ca2+-binding protein, EF-Hand protein superfamily[R]"]
["FKBP1B",10.297818,42.83672,2.05650934,{"v":6.41e-88,"d":"6.41E-88"},{"v":3.97e-87,"d":"3.97E-87"},"up","FKBP1B","FK506 binding protein 1B","GO:0000413;GO:0003755;GO:0005528;GO:0010881;GO:0016853;GO:0033017;GO:0061077","-","KOG0544-FKBP-type peptidyl-prolyl cis-trans isomerase[O]"]
["DZANK1",2.862263,11.900496,2.055793559,{"v":5.7e-79,"d":"5.70E-79"},{"v":3.29e-78,"d":"3.29E-78"},"up","DZANK1","double zinc ribbon and ankyrin repeat domains 1","-","-","KOG0195-Integrin-linked kinase[T]"]
["SPAG1",5.511624,22.911959,2.055551439,{"v":8.12e-212,"d":"8.12E-212"},{"v":9.36e-211,"d":"9.36E-211"},"up","SPAG1","-","GO:0003677;GO:0003899;GO:0005737;GO:0005829;GO:0006351","-","KOG4234-TPR repeat-containing protein[R]"]
["PRRG1",8.019715,33.330452,2.055218009,0,0,"up","PRRG1","proline rich and Gla domain 1","GO:0005509;GO:0005576;GO:0016020;GO:0016021","-","-"]
["CCLI5",9.091493,37.757401,2.054170324,{"v":3.82e-84,"d":"3.82E-84"},{"v":2.3e-83,"d":"2.30E-83"},"up","CCLI5","chemokine","GO:0002548;GO:0005125;GO:0005576;GO:0005615;GO:0006935;GO:0006954;GO:0006955;GO:0007186;GO:0008009;GO:0010469;GO:0030593;GO:0043547;GO:0048020;GO:0048247;GO:0070098;GO:0070374;GO:0071346;GO:0071347;GO:0071356","-","-"]
["COL8A1",4.616671,19.160881,2.053239067,{"v":2.76e-210,"d":"2.76E-210"},{"v":3.16e-209,"d":"3.16E-209"},"up","COL8A1","collagen type VIII alpha 1 chain","GO:0001525;GO:0005576;GO:0005581;GO:0005604;GO:0007155;GO:0010811;GO:0035987;GO:0048593;GO:0050673","-","KOG3546-Collagens (type XV)[W]"]
["ADSL",58.068016,240.663315,2.051200597,0,0,"up","ADSL","adenylosuccinate lyase","GO:0003824;GO:0004018;GO:0005829;GO:0006164;GO:0006189;GO:0009152;GO:0016829;GO:0044208;GO:0070626;GO:0003824;GO:0004018;GO:0006164;GO:0006189;GO:0009152;GO:0016829;GO:0044208;GO:0070626","K01756-ko00230 Purine metabolism;ko00250 Alanine, aspartate and glutamate metabolism","KOG2700-Adenylosuccinate lyase[F]"]
["RASD1",5.559633,22.866297,2.040161196,{"v":7.02e-100,"d":"7.02E-100"},{"v":4.7e-99,"d":"4.70E-99"},"up","RASD1","ras related dexamethasone induced 1","GO:0000166;GO:0003924;GO:0005525;GO:0007165;GO:0016020;GO:0016529","-","KOG0395-Ras-related GTPase[R]"]
["CDKL1",6.802505,27.964746,2.03947121,{"v":1.56e-147,"d":"1.56E-147"},{"v":1.36e-146,"d":"1.36E-146"},"up","CDKL1","-","GO:0000166;GO:0004672;GO:0004674;GO:0004693;GO:0005524;GO:0005634;GO:0005654;GO:0006468;GO:0043231;GO:0051726","-","KOG0593-Predicted protein kinase KKIAMRE[R]"]
["SLC7A6",12.369619,50.730522,2.036052941,0,0,"up","SLC7A6","-","GO:0005886;GO:0016020;GO:0016021;GO:0022857;GO:0043231;GO:0055085;GO:0016020;GO:0016021;GO:0022857;GO:0055085","-","-"]
["LOC107050595",162.407867,665.229797,2.034231273,0,0,"up","LOC107050595","-","-","-","-"]
["LIMCH1",8.960316,36.521557,2.027126755,0,0,"up","LIMCH1","-","GO:0046872","-","-"]
["IRX2",2.013636,8.191266,2.02428353,{"v":1.56e-75,"d":"1.56E-75"},{"v":8.79e-75,"d":"8.79E-75"},"up","IRX2","iroquois homeobox 2","-","-","KOG0773-Transcription factor MEIS1 and related HOX domain proteins[K]"]
["LOC107054964",2.280905,9.272566,2.023362272,{"v":1.62e-69,"d":"1.62E-69"},{"v":8.7e-69,"d":"8.70E-69"},"up","LOC107054964","-","-","-","-"]
["MIR2954",1.932591,7.820643,2.01675088,0.001864309,0.002804722,"up","MIR2954","microRNA 2954","-","-","-"]
["PDE4C",2.656576,10.732788,2.014384995,{"v":9.4e-93,"d":"9.40E-93"},{"v":6.02e-92,"d":"6.02E-92"},"up","PDE4C","-","GO:0004114;GO:0005929;GO:0007165;GO:0008081;GO:0016787;GO:0046872","K13293-ko00230 Purine metabolism;ko04024 cAMP signaling pathway;ko05032 Morphine addiction","-"]
["SRPX2",2.889415,11.633592,2.009447279,{"v":1.8e-84,"d":"1.80E-84"},{"v":1.09e-83,"d":"1.09E-83"},"up","SRPX2","-","GO:0005102;GO:0005615;GO:0005737;GO:0036458;GO:0042325;GO:0042802;GO:0048870;GO:0051965;GO:0071625;GO:0090050;GO:0098609","-","-"]
["TSPAN7",7.076392,28.461714,2.007936671,{"v":8.54e-146,"d":"8.54E-146"},{"v":7.44e-145,"d":"7.44E-145"},"up","TSPAN7","-","GO:0005887;GO:0007166;GO:0016020;GO:0016021","-","-"]
["RASGEF1A",14.700248,58.836243,2.000864632,0,0,"up","RASGEF1A","-","GO:0005085;GO:0005088;GO:0005622;GO:0007264;GO:0016477;GO:0046579;GO:0005085;GO:0005622;GO:0007264","-","KOG3541-Predicted guanine nucleotide exchange factor[T]"]
["GDPD5",3.067109,12.260344,1.999048115,{"v":9.13e-132,"d":"9.13E-132"},{"v":7.42e-131,"d":"7.42E-131"},"up","GDPD5","glycerophosphodiester phosphodiesterase domain containing 5","GO:0005515;GO:0005737;GO:0006629;GO:0007399;GO:0008081;GO:0008889;GO:0012505;GO:0016020;GO:0016021;GO:0016787;GO:0030426;GO:0042995;GO:0045666;GO:0048471;GO:0006629;GO:0008081;GO:0008889;GO:0016020;GO:0016021;GO:0021522;GO:0021895;GO:0030424;GO:0031175;GO:0043025;GO:0045666;GO:0045746;GO:0045787;GO:0047389;GO:0048505;GO:0097038","-","KOG2258-Glycerophosphoryl diester phosphodiesterase[C]"]
["TEKT2",2.978309,11.884342,1.996496681,{"v":1.53e-33,"d":"1.53E-33"},{"v":5.65e-33,"d":"5.65E-33"},"up","TEKT2","-","GO:0005623;GO:0005634;GO:0005815;GO:0030317;GO:0036126;GO:0036159;GO:0060271;GO:0060294","-","KOG2685-Cystoskeletal protein Tektin[Z]"]
["DNAAF2",3.843038,15.316242,1.994743213,{"v":8.18e-136,"d":"8.18E-136"},{"v":6.79e-135,"d":"6.79E-135"},"up","DNAAF2","-","GO:0005737;GO:0005829;GO:0060285;GO:0070286","-","KOG4356-Uncharacterized conserved protein[S]"]
["LOC112533095",5.649341,22.513866,1.994659322,{"v":5.21e-12,"d":"5.21E-12"},{"v":1.23e-11,"d":"1.23E-11"},"up","LOC112533095","-","-","-","-"]
["LMLN",1.479443,5.893189,1.993994422,{"v":5.87e-100,"d":"5.87E-100"},{"v":3.94e-99,"d":"3.94E-99"},"up","LMLN","-","GO:0004222;GO:0005829;GO:0005925;GO:0006508;GO:0007155;GO:0016020;GO:0016021","-","KOG2556-Leishmanolysin-like peptidase (Peptidase M8 family)[MV]"]
["PKIA",9.882048,39.27412,1.990696981,{"v":1.64e-40,"d":"1.64E-40"},{"v":6.65e-40,"d":"6.65E-40"},"up","PKIA","protein kinase (cAMP-dependent, catalytic) inhibitor alpha","GO:0004860;GO:0004862;GO:0005634;GO:0005737;GO:0006469;GO:2000480","-","-"]
["LOC112533379",1.764761,7.008646,1.989662943,{"v":4.05e-39,"d":"4.05E-39"},{"v":1.61e-38,"d":"1.61E-38"},"up","LOC112533379","-","-","-","-"]
["ARSI",2.136271,8.425879,1.979732524,{"v":3.88e-100,"d":"3.88E-100"},{"v":2.6e-99,"d":"2.60E-99"},"up","ARSI","-","GO:0003824;GO:0008152;GO:0008484","-","KOG3867-Sulfatase[R]"]
["NINJ2",27.725855,108.920677,1.973973999,0,0,"up","NINJ2","-","GO:0007155;GO:0016020;GO:0016021;GO:0042246","-","-"]
["BCO2",1.894407,7.439843,1.97352586,{"v":1.08e-45,"d":"1.08E-45"},{"v":4.67e-45,"d":"4.67E-45"},"up","BCO2","-","GO:0005739;GO:0016116;GO:0016119;GO:0016121;GO:0016122;GO:0016702;GO:0042574;GO:0046872;GO:0051881;GO:0055114;GO:2000377","-","KOG1285-Beta, beta-carotene 15,15'-dioxygenase and related enzymes[Q]"]
["STEAP3",2.754205,10.748725,1.964457689,{"v":1.85e-31,"d":"1.85E-31"},{"v":6.61e-31,"d":"6.61E-31"},"up","STEAP3","-","GO:0005737;GO:0005768;GO:0005771;GO:0005887;GO:0008823;GO:0009306;GO:0015677;GO:0016020;GO:0016021;GO:0052851;GO:0055114;GO:0098706","K10142-ko04115 p53 signaling pathway","-"]
["MIR30B",7.374216,28.697527,1.960364838,0.000556631,0.000878905,"up","MIR30B","microRNA 30b","-","-","-"]
["TWF2",38.654819,150.36731,1.95977077,0,0,"up","TWF2","twinfilin actin binding protein 2","GO:0003779;GO:0003785;GO:0005080;GO:0005524;GO:0005546;GO:0005622;GO:0005737;GO:0010592;GO:0010976;GO:0030027;GO:0030175;GO:0030426;GO:0030837;GO:0032420;GO:0032956;GO:0045773;GO:0048471;GO:0071300;GO:0071363;GO:0003779;GO:0005622;GO:0005737;GO:0005856;GO:0030837;GO:0048471","-","KOG1747-Protein tyrosine kinase 9/actin monomer-binding protein[W]"]
["KCNJ5",1.567353,6.072468,1.953952841,{"v":6.58e-36,"d":"6.58E-36"},{"v":2.5e-35,"d":"2.50E-35"},"up","KCNJ5","-","GO:0005242;GO:0005244;GO:0005887;GO:0006811;GO:0006813;GO:0008076;GO:0015467;GO:0016020;GO:0016021;GO:0034220;GO:0034765;GO:0071805;GO:0086089;GO:0086091;GO:0098914;GO:1990573","-","KOG3827-Inward rectifier K+ channel[P]"]
["MYLK3",4.406188,17.038113,1.951162606,{"v":3.93e-216,"d":"3.93E-216"},{"v":4.62e-215,"d":"4.62E-215"},"up","MYLK3","-","GO:0002528;GO:0004672;GO:0004683;GO:0004687;GO:0005524;GO:0005622;GO:0005737;GO:0006468;GO:0015629;GO:0018105;GO:0018107;GO:0035556;GO:0045214;GO:0048769;GO:0055003;GO:0071347","K00907-ko04020 Calcium signaling pathway;ko04022 cGMP - PKG signaling pathway;ko04810 Regulation of actin cytoskeleton;ko04510 Focal adhesion;ko04611 Platelet activation;ko04921 Oxytocin signaling pathway;ko04270 Vascular smooth muscle contraction;ko04971 Gastric acid secretion","KOG0032-Ca2+/calmodulin-dependent protein kinase, EF-Hand protein superfamily[T]"]
["FOXO3",14.08583,54.366352,1.94846945,0,0,"up","FOXO3","-","GO:0000122;GO:0000978;GO:0000981;GO:0001227;GO:0001228;GO:0001542;GO:0001544;GO:0001547;GO:0001556;GO:0003677;GO:0003700;GO:0005634;GO:0005654;GO:0005737;GO:0005739;GO:0005741;GO:0005759;GO:0005829;GO:0006351;GO:0006355;GO:0006357;GO:0006366;GO:0006390;GO:0006417;GO:0008013;GO:0009653;GO:0016020;GO:0019901;GO:0030154;GO:0030330;GO:0030336;GO:0031490;GO:0032991;GO:0033209;GO:0034246;GO:0034599;GO:0042593;GO:0043065;GO:0043525;GO:0043565;GO:0045648;GO:0045893;GO:0045944;GO:0048854;GO:0090090;GO:0097150;GO:0097192;GO:2000177;GO:2000377","K09408-ko04068 FoxO signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04152 AMPK signaling pathway;ko04062 Chemokine signaling pathway;ko04917 Prolactin signaling pathway;ko04722 Neurotrophin signaling pathway;ko04211 Longevity regulating pathway - mammal;ko04212 Longevity regulating pathway - worm;ko04213 Longevity regulating pathway - multiple species;ko05213 Endometrial cancer;ko05223 Non-small cell lung cancer;ko01521 EGFR tyrosine kinase inhibitor resistance","KOG4385-Predicted forkhead transcription factor[K]"]
["SULT4A1",10.980247,42.335808,1.946967916,{"v":1.1e-290,"d":"1.10E-290"},{"v":1.62e-289,"d":"1.62E-289"},"up","SULT4A1","-","GO:0006790;GO:0008146;GO:0016740;GO:0042802","-","KOG1584-Sulfotransferase[R]"]
["THRSPB",3.088476,11.899972,1.945991154,{"v":1.77e-21,"d":"1.77E-21"},{"v":5.29e-21,"d":"5.29E-21"},"up","THRSPB","thyroid hormone responsive spot 14 beta","-","-","-"]
["LMX1A",2.271772,8.743931,1.944463966,{"v":6.48e-38,"d":"6.48E-38"},{"v":2.53e-37,"d":"2.53E-37"},"up","LMX1A","LIM homeobox transcription factor 1, alpha","GO:0000977;GO:0001228;GO:0001558;GO:0003677;GO:0005634;GO:0006355;GO:0006366;GO:0007411;GO:0007417;GO:0007613;GO:0007626;GO:0010468;GO:0021542;GO:0021549;GO:0021766;GO:0021953;GO:0030182;GO:0030901;GO:0042048;GO:0043565;GO:0045665;GO:0045944;GO:0046872;GO:0050808;GO:0071542;GO:1904948","-","KOG4577-Transcription factor LIM3, contains LIM and HOX domains[K]"]
["TNFRSF14",10.956249,42.164192,1.944264349,{"v":5.58e-129,"d":"5.58E-129"},{"v":4.46e-128,"d":"4.46E-128"},"up","TNFRSF14","-","GO:0007165;GO:0016020;GO:0016021","-","-"]
["SGMS1",21.343775,81.936584,1.940692384,0,0,"up","SGMS1","sphingomyelin synthase 1","GO:0000138;GO:0002950;GO:0006686;GO:0016020;GO:0016021;GO:0030173;GO:0033188;GO:0046513;GO:0047493;GO:2001237;GO:0000139;GO:0005794;GO:0005887;GO:0006629;GO:0006665;GO:0006686;GO:0006915;GO:0006954;GO:0016020;GO:0016021;GO:0016301;GO:0016310;GO:0016740;GO:0030173;GO:0030176;GO:0033188;GO:0043066;GO:0046513;GO:0047493","K04714-ko00600 Sphingolipid metabolism;ko04071 Sphingolipid signaling pathway","KOG3058-Uncharacterized conserved protein[S]"]
["HSPB8",101.183243,388.255829,1.9400372,0,0,"up","HSPB8","-","GO:0005622;GO:0005634;GO:0005737;GO:0005829;GO:0042802","-","KOG3591-Alpha crystallins[O]"]
["CLDN11",2.75303,10.425584,1.921035964,{"v":4.24e-43,"d":"4.24E-43"},{"v":1.77e-42,"d":"1.77E-42"},"up","CLDN11","-","GO:0005198;GO:0005886;GO:0005923;GO:0007155;GO:0007283;GO:0008366;GO:0016020;GO:0016021;GO:0030054;GO:0043209;GO:0045178","K06087-ko04514 Cell adhesion molecules (CAMs);ko04530 Tight junction;ko04670 Leukocyte transendothelial migration;ko05160 Hepatitis C","-"]
["LGI2",1.438393,5.445868,1.920704109,{"v":1.18e-63,"d":"1.18E-63"},{"v":6.03e-63,"d":"6.03E-63"},"up","LGI2","leucine-rich repeat LGI family, member 2","-","-","KOG4237-Extracellular matrix protein slit, contains leucine-rich and EGF-like repeats[WT]"]
["F3",176.659622,668.717163,1.920423816,0,0,"up","F3","-","GO:0004896;GO:0005886;GO:0007596;GO:0016020;GO:0016021;GO:0019221","K03901-ko04610 Complement and coagulation cascades;ko04933 AGE-RAGE signaling pathway in diabetic complications","-"]
["LOC112530257",1.423265,5.380175,1.918448795,{"v":2.77e-53,"d":"2.77E-53"},{"v":1.29e-52,"d":"1.29E-52"},"up","LOC112530257","-","-","-","-"]
["LOC112533088",2.838667,10.722322,1.917331843,0.000202252,0.000330929,"up","LOC112533088","-","-","-","-"]
["GFPT2",30.69717,115.823845,1.915754732,0,0,"up","GFPT2","-","GO:0004360;GO:0097367;GO:1901135;GO:1901137;GO:1990830","K00820-ko00520 Amino sugar and nucleotide sugar metabolism;ko00250 Alanine, aspartate and glutamate metabolism;ko04931 Insulin resistance","KOG1268-Glucosamine 6-phosphate synthetases, contain amidotransferase and phosphosugar isomerase domains[M]"]
["SOCS3",8.371341,31.572182,1.91512332,{"v":9.49e-140,"d":"9.49E-140"},{"v":8e-139,"d":"8.00E-139"},"up","SOCS3","suppressor of cytokine signaling 3","GO:0001784;GO:0001932;GO:0004860;GO:0005622;GO:0005737;GO:0006469;GO:0007259;GO:0009968;GO:0016567;GO:0019221;GO:0035556;GO:0040008;GO:0042532;GO:0043066;GO:0045595;GO:0045597;GO:0046426;GO:0046627;GO:0050728;GO:1990830","K04696-ko04120 Ubiquitin mediated proteolysis;ko04630 Jak-STAT signaling pathway;ko04668 TNF signaling pathway;ko04910 Insulin signaling pathway;ko04920 Adipocytokine signaling pathway;ko04917 Prolactin signaling pathway;ko04380 Osteoclast differentiation;ko04930 Type II diabetes mellitus;ko04932 Non-alcoholic fatty liver disease (NAFLD);ko04931 Insulin resistance;ko05164 Influenza A;ko05160 Hepatitis C;ko05168 Herpes simplex infection","KOG4566-Cytokine-inducible SH2 protein[T]"]
["GLDN",3.615247,13.567382,1.907976238,{"v":1.98e-78,"d":"1.98E-78"},{"v":1.14e-77,"d":"1.14E-77"},"up","GLDN","-","GO:0005615;GO:0005886;GO:0032528;GO:0034113;GO:0045162;GO:0086080","-","KOG3545-Olfactomedin and related extracellular matrix glycoproteins[W]"]
["CEP85",7.71035,28.824871,1.902445896,0,0,"up","CEP85","-","GO:0000242;GO:0000922;GO:0005730;GO:0005739;GO:0005794;GO:0005813;GO:0005815;GO:0005829;GO:0006469;GO:0046602","-","-"]
["PAPSS2",24.063416,89.78788,1.899679257,0,0,"up","PAPSS2","-","GO:0000103;GO:0004020;GO:0004781;GO:0005524;GO:0007596;GO:0016310;GO:0050428;GO:0060348","K13811-ko00920 Sulfur metabolism;ko00230 Purine metabolism;ko00450 Selenocompound metabolism;ko00261 Monobactam biosynthesis","KOG4238-Bifunctional ATP sulfurylase/adenosine 5'-phosphosulfate kinase[F]"]
["KCNK5",1.723415,6.42278,1.897927735,{"v":8.8e-93,"d":"8.80E-93"},{"v":5.64e-92,"d":"5.64E-92"},"up","KCNK5","-","GO:0005249;GO:0005267;GO:0006811;GO:0016020;GO:0016021;GO:0071805","-","KOG4404-Tandem pore domain K+ channel TASK3/THIK-1[P]"]
["FGF18",2.956834,10.947565,1.888484859,{"v":4.21e-20,"d":"4.21E-20"},{"v":1.22e-19,"d":"1.22E-19"},"up","FGF18","fibroblast growth factor 18","GO:0005104;GO:0005576;GO:0008083;GO:0008543;GO:0010469","K04358-ko04014 Ras signaling pathway;ko04015 Rap1 signaling pathway;ko04010 MAPK signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04810 Regulation of actin cytoskeleton;ko05200 Pathways in cancer;ko05218 Melanoma;ko05224 Breast cancer","KOG3885-Fibroblast growth factor[T]"]
["GNLY",5.520107,20.432869,1.888123651,{"v":4.03e-43,"d":"4.03E-43"},{"v":1.69e-42,"d":"1.69E-42"},"up","GNLY","granulysin","GO:0006629;GO:0042742","-","KOG1340-Prosaposin[IG]"]
["LOC107053477",1.809279,6.689723,1.886531579,{"v":2.23e-97,"d":"2.23E-97"},{"v":1.47e-96,"d":"1.47E-96"},"up","LOC107053477","-","-","-","-"]
["PCOLCE2",36.981163,136.549896,1.884565714,0,0,"up","PCOLCE2","-","GO:0005518;GO:0005576;GO:0008201;GO:0010952;GO:0016504;GO:1990830","-","KOG4292-Cubilin, multiligand receptor mediating cobalamin absorption[H]"]
["PDE4B",6.259577,23.089642,1.883108731,{"v":1.57e-180,"d":"1.57E-180"},{"v":1.6e-179,"d":"1.60E-179"},"up","PDE4B","phosphodiesterase 4B","GO:0000930;GO:0001780;GO:0004114;GO:0004115;GO:0005813;GO:0005829;GO:0007165;GO:0008021;GO:0008081;GO:0014069;GO:0016020;GO:0016787;GO:0030552;GO:0030593;GO:0032729;GO:0032743;GO:0035690;GO:0043015;GO:0043197;GO:0046872;GO:0050852;GO:0050900;GO:0060076;GO:0071222;GO:0071944","K13293-ko00230 Purine metabolism;ko04024 cAMP signaling pathway;ko05032 Morphine addiction","KOG3689-Cyclic nucleotide phosphodiesterase[T]"]
["CLCN4",2.999737,11.00966,1.875861992,{"v":1.62e-171,"d":"1.62E-171"},{"v":1.59e-170,"d":"1.59E-170"},"up","CLCN4","-","GO:0005247;GO:0005254;GO:0005789;GO:0005887;GO:0006811;GO:0006821;GO:0015297;GO:0016020;GO:0016021;GO:0055085;GO:1902476","-","KOG0475-Cl- channel CLC-3 and related proteins (CLC superfamily)[P]"]
["SBK1",4.756068,17.357883,1.867749757,{"v":2.02e-105,"d":"2.02E-105"},{"v":1.4e-104,"d":"1.40E-104"},"up","SBK1","-","GO:0000166;GO:0004672;GO:0004674;GO:0005524;GO:0005737;GO:0006468;GO:0016740;GO:0018105;GO:0018107","-","KOG1345-Serine/threonine kinase[T]"]
["SELE",1.405487,5.118392,1.864620533,{"v":2.1e-108,"d":"2.10E-108"},{"v":1.49e-107,"d":"1.49E-107"},"up","SELE","-","GO:0007155;GO:0016020;GO:0016021","K06494-ko04668 TNF signaling pathway;ko04514 Cell adhesion molecules (CAMs);ko04933 AGE-RAGE signaling pathway in diabetic complications;ko05144 Malaria;ko05143 African trypanosomiasis","-"]
["TNMD",1.532988,5.573389,1.862208447,{"v":1.1e-16,"d":"1.10E-16"},{"v":2.97e-16,"d":"2.97E-16"},"up","TNMD","tenomodulin","GO:0001886;GO:0001937;GO:0016020;GO:0016021;GO:0016525","-","-"]
["NME5",7.393062,26.815575,1.858827272,{"v":1.09e-150,"d":"1.09E-150"},{"v":9.71e-150,"d":"9.71E-150"},"up","NME5","NME/NM23 family member 5","GO:0003351;GO:0004550;GO:0006165;GO:0006183;GO:0006228;GO:0006241;GO:0007286;GO:0021591;GO:0036126;GO:0048515;GO:0060271;GO:1902176","-","KOG0888-Nucleoside diphosphate kinase[F]"]
["BBS5",7.977129,28.896656,1.856961036,{"v":1.75e-157,"d":"1.75E-157"},{"v":1.61e-156,"d":"1.61E-156"},"up","BBS5","Bardet-Biedl syndrome 5","GO:0005929;GO:0005930;GO:0032266;GO:0034451;GO:0034464;GO:0036064;GO:0046907;GO:0060271","-","-"]
["B9D2",3.634859,13.165432,1.856783555,{"v":2.51e-25,"d":"2.51E-25"},{"v":8.07e-25,"d":"8.07E-25"},"up","B9D2","-","-","-","-"]
["ZNF827",4.071939,14.715784,1.853576551,{"v":3.51e-142,"d":"3.51E-142"},{"v":3.01e-141,"d":"3.01E-141"},"up","ZNF827","-","GO:0003676","-","KOG3623-Homeobox transcription factor SIP1[K]"]
["CATH3",3.001231,10.835096,1.852085666,{"v":2.23e-89,"d":"2.23E-89"},{"v":1.39e-88,"d":"1.39E-88"},"up","CATH3","cathelicidin-3","GO:0005576;GO:0006952;GO:0016020;GO:0016021","-","-"]
["LOC107053119",3.191452,11.509152,1.850496684,{"v":3.48e-32,"d":"3.48E-32"},{"v":1.26e-31,"d":"1.26E-31"},"up","LOC107053119","-","-","-","-"]
["CSF3R",2.199982,7.904668,1.84521315,{"v":3.39e-54,"d":"3.39E-54"},{"v":1.59e-53,"d":"1.59E-53"},"up","CSF3R","colony stimulating factor 3 receptor","GO:0004896;GO:0016020;GO:0016021;GO:0019221;GO:0030593;GO:0045637;GO:0051916","K05061-ko04630 Jak-STAT signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04060 Cytokine-cytokine receptor interaction;ko04640 Hematopoietic cell lineage;ko05200 Pathways in cancer","KOG4221-Receptor mediating netrin-dependent axon guidance[T]"]
["LOC422442",13.137488,47.138039,1.843202296,{"v":1.05e-115,"d":"1.05E-115"},{"v":7.82e-115,"d":"7.82E-115"},"up","LOC422442","-","GO:0016020;GO:0016021","-","-"]
["SSH2",4.526148,16.201147,1.839740291,{"v":1.41e-249,"d":"1.41E-249"},{"v":1.85e-248,"d":"1.85E-248"},"up","SSH2","-","GO:0003779;GO:0004725;GO:0005737;GO:0006470;GO:0008064;GO:0008138;GO:0010591;GO:0016311;GO:0016787;GO:0016791;GO:0035335;GO:0050770","K05766-ko04810 Regulation of actin cytoskeleton;ko04360 Axon guidance","KOG1716-Dual specificity phosphatase[V]"]
["LOC776376",1.57409,5.63261,1.839285553,{"v":1.1e-16,"d":"1.10E-16"},{"v":2.97e-16,"d":"2.97E-16"},"up","LOC776376","C-reactive protein, pentraxin-related","-","-","-"]
["AQP4",3.294376,11.780836,1.83836479,{"v":1.21e-125,"d":"1.21E-125"},{"v":9.46e-125,"d":"9.46E-125"},"up","AQP4","aquaporin 4","GO:0005737;GO:0005886;GO:0005887;GO:0006833;GO:0009897;GO:0015250;GO:0015267;GO:0016020;GO:0016021;GO:0016323;GO:0034220;GO:0050891;GO:0055085;GO:0071346","-","KOG0223-Aquaporin (major intrinsic protein family)[G]"]
["SCD5",10.784071,38.54459,1.837626482,{"v":5.55e-214,"d":"5.55E-214"},{"v":6.46e-213,"d":"6.46E-213"},"up","SCD5","-","GO:0004768;GO:0005789;GO:0006629;GO:0006633;GO:0006636;GO:0016020;GO:0016021;GO:0016491;GO:0016717;GO:0055114","K00507-ko01212 Fatty acid metabolism;ko01040 Biosynthesis of unsaturated fatty acids;ko04152 AMPK signaling pathway;ko03320 PPAR signaling pathway;ko04212 Longevity regulating pathway - worm","KOG1600-Fatty acid desaturase[I]"]
["MIR7-1",1.896106,6.772447,1.836637579,0.00970096,0.013586386,"up","MIR7-1","microRNA 7-1","-","-","-"]
["ST7",7.361992,26.187267,1.830697415,{"v":1.22e-136,"d":"1.22E-136"},{"v":1.01e-135,"d":"1.01E-135"},"up","ST7","suppression of tumorigenicity 7","GO:0016020;GO:0016021","-","KOG3807-Predicted membrane protein ST7 (tumor suppressor in humans)[R]"]
["SLC16A9",10.665699,37.823967,1.826322163,{"v":7.75e-216,"d":"7.75E-216"},{"v":9.07e-215,"d":"9.07E-215"},"up","SLC16A9","solute carrier family 16 member 9","GO:0016020;GO:0016021;GO:0055085;GO:0005886;GO:0005887;GO:0008028;GO:0015293;GO:0015718;GO:0016020;GO:0016021;GO:0055085","-","KOG2504-Monocarboxylate transporter[G]"]
["ST3GAL1",19.68047,69.772278,1.825889262,0,0,"up","ST3GAL1","ST3 beta-galactoside alpha-2,3-sialyltransferase 1","GO:0005794;GO:0006486;GO:0008373;GO:0016020;GO:0016021;GO:0016740;GO:0016757;GO:0097503;GO:0000139;GO:0003836;GO:0005576;GO:0005794;GO:0006054;GO:0006486;GO:0006487;GO:0008373;GO:0009311;GO:0016020;GO:0016021;GO:0016740;GO:0016757;GO:0018279;GO:0032580;GO:0097503","K00780-ko00512 Mucin type O-glycan biosynthesis;ko00533 Glycosaminoglycan biosynthesis - keratan sulfate;ko00603 Glycosphingolipid biosynthesis - globo series;ko00604 Glycosphingolipid biosynthesis - ganglio series","KOG2692-Sialyltransferase[G]"]
["TIAM2",3.04289,10.779258,1.824743786,{"v":7.76e-132,"d":"7.76E-132"},{"v":6.31e-131,"d":"6.31E-131"},"up","TIAM2","T-cell lymphoma invasion and metastasis 2","GO:0005085;GO:0005089;GO:0005096;GO:0005737;GO:0007165;GO:0016020;GO:0035023;GO:0035556;GO:0043547","-","KOG3519-Invasion-inducing protein TIAM1/CDC24 and related RhoGEF GTPases[T]"]
["TRIM58",10.493018,37.109375,1.822354018,{"v":1.51e-148,"d":"1.51E-148"},{"v":1.33e-147,"d":"1.33E-147"},"up","TRIM58","-","GO:0005622;GO:0008270;GO:0046872","-","-"]
["CORO2A",1.934184,6.836936,1.821624875,{"v":4e-67,"d":"4.00E-67"},{"v":2.11e-66,"d":"2.11E-66"},"up","CORO2A","-","GO:0015629;GO:0017053;GO:0030036;GO:0051015","-","KOG0303-Actin-binding protein Coronin, contains WD40 repeats[Z]"]
["PLEKHS1",11.432868,40.407337,1.821429918,{"v":4.59e-241,"d":"4.59E-241"},{"v":5.85e-240,"d":"5.85E-240"},"up","PLEKHS1","-","-","-","-"]
["TEX9",5.653253,19.96509,1.820326407,{"v":2.6e-167,"d":"2.60E-167"},{"v":2.5e-166,"d":"2.50E-166"},"up","TEX9","-","-","-","-"]
["OPTN",40.100468,141.130035,1.815334073,0,0,"up","OPTN","optineurin","GO:0001920;GO:0005634;GO:0005737;GO:0005768;GO:0005776;GO:0005794;GO:0005802;GO:0005829;GO:0006914;GO:0007030;GO:0008022;GO:0010508;GO:0016192;GO:0017137;GO:0030674;GO:0031410;GO:0031593;GO:0034067;GO:0034613;GO:0034620;GO:0042802;GO:0043001;GO:0043122;GO:0043124;GO:0046872;GO:0048471;GO:0050829;GO:0055037;GO:0061734;GO:0070530;GO:0090161;GO:1904417","-","-"]
["LPAR4",10.098763,35.511322,1.814100482,{"v":4.52e-216,"d":"4.52E-216"},{"v":5.3e-215,"d":"5.30E-215"},"up","LPAR4","lysophosphatidic acid receptor 4","GO:0004930;GO:0005886;GO:0005887;GO:0007165;GO:0007186;GO:0016020;GO:0016021;GO:0016604;GO:0035025;GO:0035727;GO:0043231;GO:0051482;GO:0070915","K04275-ko04015 Rap1 signaling pathway;ko04072 Phospholipase D signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04080 Neuroactive ligand-receptor interaction;ko05200 Pathways in cancer","KOG4219-G protein-coupled receptor[T]"]
["SLC16A12",2.372444,8.338895,1.813482189,{"v":9.87e-76,"d":"9.87E-76"},{"v":5.56e-75,"d":"5.56E-75"},"up","SLC16A12","-","GO:0005887;GO:0008028;GO:0015718;GO:0016020;GO:0016021;GO:0055085","-","KOG2504-Monocarboxylate transporter[G]"]
["IFT172",5.345128,18.784786,1.813268279,{"v":7.19e-229,"d":"7.19E-229"},{"v":8.82e-228,"d":"8.82E-228"},"up","IFT172","-","GO:0001841;GO:0001843;GO:0001947;GO:0005929;GO:0005930;GO:0007219;GO:0007224;GO:0007368;GO:0007420;GO:0007507;GO:0008544;GO:0008589;GO:0009953;GO:0016485;GO:0021522;GO:0021915;GO:0030992;GO:0031122;GO:0036064;GO:0045880;GO:0050680;GO:0060021;GO:0060173;GO:0060271;GO:0060348;GO:0061525;GO:0070986;GO:0097225;GO:0097228;GO:0097598;GO:1905515","-","KOG3616-Selective LIM binding factor[K]"]
["HSPB9",25.148233,88.369736,1.813095339,{"v":3.89e-199,"d":"3.89E-199"},{"v":4.25e-198,"d":"4.25E-198"},"up","HSPB9","heat shock protein family B (small) member 9","-","-","-"]
["RGS22",1.777619,6.244883,1.812728401,{"v":1.78e-85,"d":"1.78E-85"},{"v":1.08e-84,"d":"1.08E-84"},"up","RGS22","-","-","-","-"]
["EIF4E3",5.206655,18.28373,1.8121317,{"v":1.22e-68,"d":"1.22E-68"},{"v":6.54e-68,"d":"6.54E-68"},"up","EIF4E3","-","GO:0003723;GO:0003743;GO:0005737;GO:0006412;GO:0006413","-","KOG1669-Predicted mRNA cap-binding protein related to eIF-4E[J]"]
["TMEM120A",18.842257,65.937134,1.807119394,{"v":2.41e-238,"d":"2.41E-238"},{"v":3.05e-237,"d":"3.05E-237"},"up","TMEM120A","-","GO:0016020;GO:0016021;GO:0045444","-","KOG4758-Predicted membrane protein[R]"]
["BNIP3",133.065781,465.513428,1.806683166,0,0,"up","BNIP3","-","GO:0005635;GO:0005739;GO:0005740;GO:0005741;GO:0005783;GO:0006915;GO:0008626;GO:0009617;GO:0010637;GO:0010821;GO:0014069;GO:0016020;GO:0016021;GO:0016239;GO:0031307;GO:0031966;GO:0035694;GO:0042802;GO:0042803;GO:0043065;GO:0043066;GO:0043068;GO:0043243;GO:0043653;GO:0045837;GO:0046902;GO:0046982;GO:0051020;GO:0051607;GO:0060548;GO:0071260;GO:0071279;GO:0071456;GO:0072593;GO:0090141;GO:0090200;GO:0097193;GO:0097345;GO:1901998;GO:1903715;GO:1990144;GO:2000378","K15464-ko04068 FoxO signaling pathway;ko05134 Legionellosis","-"]
["DLEC1",4.038406,14.12067,1.805950679,{"v":4.91e-200,"d":"4.91E-200"},{"v":5.39e-199,"d":"5.39E-199"},"up","DLEC1","-","GO:0005737;GO:0005829;GO:0008285","-","-"]
["CD164L2",16.206024,56.626289,1.804941804,{"v":1.79e-190,"d":"1.79E-190"},{"v":1.89e-189,"d":"1.89E-189"},"up","CD164L2","-","GO:0016020;GO:0016021","-","-"]
["LOC112529922",39.773476,138.958267,1.80477311,{"v":5.6e-240,"d":"5.60E-240"},{"v":7.11e-239,"d":"7.11E-239"},"up","LOC112529922","-","-","-","-"]
["CMPK2",3.210055,11.200615,1.802908028,{"v":1.56e-84,"d":"1.56E-84"},{"v":9.41e-84,"d":"9.41E-84"},"up","CMPK2","-","GO:0004127;GO:0004550;GO:0004798;GO:0005524;GO:0005737;GO:0005739;GO:0006165;GO:0006227;GO:0006233;GO:0006235;GO:0009041;GO:0009142;GO:0033862;GO:0046940;GO:0071222","K13809-ko00240 Pyrimidine metabolism","KOG3327-Thymidylate kinase/adenylate kinase[F]"]
["EYA4",4.698771,16.388987,1.802371321,{"v":3.3e-219,"d":"3.30E-219"},{"v":3.92e-218,"d":"3.92E-218"},"up","EYA4","EYA transcriptional coactivator and phosphatase 4","GO:0004721;GO:0004725;GO:0005634;GO:0005737;GO:0006281;GO:0006325;GO:0006351;GO:0006355;GO:0006470;GO:0006974;GO:0007275;GO:0007605;GO:0016576;GO:0016787;GO:0030154;GO:0035335;GO:0045739;GO:0046872;GO:0048856;GO:2001240","-","KOG3107-Predicted haloacid dehalogenase-like hydrolase (eyes absent)[R]"]
["ACYP2",35.112419,122.269386,1.800009928,{"v":1.54e-253,"d":"1.54E-253"},{"v":2.04e-252,"d":"2.04E-252"},"up","ACYP2","acylphosphatase 2","GO:0003998;GO:0016787","K01512-ko00620 Pyruvate metabolism;ko00627 Aminobenzoate degradation","KOG3360-Acylphosphatase[C]"]
["INSR",11.595009,40.256191,1.795706733,0,0,"up","INSR","-","GO:0000166;GO:0000187;GO:0001540;GO:0001934;GO:0003007;GO:0004672;GO:0004713;GO:0004714;GO:0005009;GO:0005159;GO:0005524;GO:0005525;GO:0005635;GO:0005886;GO:0005887;GO:0005899;GO:0005901;GO:0006355;GO:0006468;GO:0007169;GO:0007186;GO:0008284;GO:0008286;GO:0008544;GO:0008584;GO:0009887;GO:0016020;GO:0016021;GO:0016301;GO:0016310;GO:0016740;GO:0018108;GO:0019087;GO:0019904;GO:0030238;GO:0030325;GO:0030335;GO:0031017;GO:0031981;GO:0031994;GO:0031995;GO:0032147;GO:0032148;GO:0032869;GO:0038083;GO:0042593;GO:0043235;GO:0043410;GO:0043548;GO:0043559;GO:0043560;GO:0044877;GO:0045429;GO:0045725;GO:0045821;GO:0045840;GO:0045893;GO:0045995;GO:0046326;GO:0046777;GO:0048639;GO:0051290;GO:0051425;GO:0051446;GO:0051897;GO:0060267;GO:0071363;GO:2000194","K04527-ko04014 Ras signaling pathway;ko04015 Rap1 signaling pathway;ko04066 HIF-1 signaling pathway;ko04068 FoxO signaling pathway;ko04072 Phospholipase D signaling pathway;ko04022 cGMP - PKG signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04152 AMPK signaling pathway;ko04150 mTOR signaling pathway;ko04520 Adherens junction;ko04910 Insulin signaling pathway;ko04923 Regulation of lipolysis in adipocyte;ko04913 Ovarian Steroidogenesis;ko04960 Aldosterone-regulated sodium reabsorption;ko04211 Longevity regulating pathway - mammal;ko04212 Longevity regulating pathway - worm;ko04213 Longevity regulating pathway - multiple species;ko04930 Type II diabetes mellitus;ko04932 Non-alcoholic fatty liver disease (NAFLD);ko04931 Insulin resistance","KOG4258-Insulin/growth factor receptor (contains protein kinase domain)[T]"]
["TMEM47",6.123078,21.227715,1.793620118,{"v":3.51e-203,"d":"3.51E-203"},{"v":3.93e-202,"d":"3.93E-202"},"up","TMEM47","-","GO:0005886;GO:0005911;GO:0016020;GO:0016021","-","KOG4671-Brain cell membrane protein 1 (BCMP1)[R]"]
["TAP1",3.471395,11.99997,1.789443359,{"v":2.37e-48,"d":"2.37E-48"},{"v":1.05e-47,"d":"1.05E-47"},"up","TAP1","transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)","GO:0000166;GO:0002479;GO:0005524;GO:0005783;GO:0005815;GO:0006952;GO:0015433;GO:0015833;GO:0016020;GO:0016021;GO:0016887;GO:0019885;GO:0023029;GO:0030176;GO:0042287;GO:0042288;GO:0042626;GO:0042825;GO:0042886;GO:0043531;GO:0046967;GO:0046979;GO:0055085;GO:1904680","K05653-ko02010 ABC transporters;ko04145 Phagosome;ko04612 Antigen processing and presentation;ko05340 Primary immunodeficiency;ko05168 Herpes simplex infection","-"]
["IRF9",7.948336,27.461893,1.788706311,{"v":7.33e-86,"d":"7.33E-86"},{"v":4.47e-85,"d":"4.47E-85"},"up","IRF9","interferon regulatory factor 9","GO:0003677;GO:0003700;GO:0005634;GO:0006351;GO:0006355;GO:0044212","-","-"]
["KIF27",2.130825,7.352487,1.786820216,{"v":5.6e-98,"d":"5.60E-98"},{"v":3.71e-97,"d":"3.71E-97"},"up","KIF27","-","GO:0000166;GO:0003351;GO:0003774;GO:0003777;GO:0005524;GO:0005871;GO:0005929;GO:0007018;GO:0008017;GO:0008574;GO:0021591;GO:0060271","-","KOG0244-Kinesin-like protein[Z]"]
["PLAGL1",2.290187,7.89744,1.785919668,{"v":1.04e-159,"d":"1.04E-159"},{"v":9.64e-159,"d":"9.64E-159"},"up","PLAGL1","-","GO:0000977;GO:0000981;GO:0003676;GO:0005634;GO:0006357;GO:0006915","-","KOG2461-Transcription factor BLIMP-1/PRDI-BF1, contains C2H2-type Zn-finger and SET domains[K]"]
["LOC423752",6.684305,23.007519,1.783255951,{"v":4e-202,"d":"4.00E-202"},{"v":4.46e-201,"d":"4.46E-201"},"up","LOC423752","-","-","-","-"]
["NAMPT",29.304598,100.845406,1.782946412,0,0,"up","NAMPT","nicotinamide phosphoribosyltransferase","GO:0003824;GO:0004514;GO:0005737;GO:0007623;GO:0009435;GO:0016607;GO:0030054;GO:0032922;GO:0042802;GO:0045944;GO:0047280;GO:0051770","K03462-ko00760 Nicotinate and nicotinamide metabolism","-"]
["TAP2",6.797057,23.277811,1.77597327,{"v":1.45e-109,"d":"1.45E-109"},{"v":1.04e-108,"d":"1.04E-108"},"up","TAP2","transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)","GO:0000166;GO:0005524;GO:0015440;GO:0016020;GO:0016021;GO:0016887;GO:0019885;GO:0030176;GO:0042287;GO:0042626;GO:0042825;GO:0042886;GO:0055085","K05654-ko02010 ABC transporters;ko04145 Phagosome;ko04612 Antigen processing and presentation;ko05340 Primary immunodeficiency;ko05168 Herpes simplex infection","-"]
["KLHL3",1.920013,6.555525,1.771595244,{"v":2.33e-38,"d":"2.33E-38"},{"v":9.17e-38,"d":"9.17E-38"},"up","KLHL3","-","GO:0005829;GO:0006511;GO:0016567;GO:0031463;GO:0050801;GO:0070294;GO:0070936;GO:0072156","-","KOG4441-Proteins containing BTB/POZ and Kelch domains, involved in regulatory/signal transduction processes[TR]"]
["SEMA6B",2.101942,7.160568,1.768351171,{"v":3.29e-54,"d":"3.29E-54"},{"v":1.54e-53,"d":"1.54E-53"},"up","SEMA6B","semaphorin 6B","GO:0005887;GO:0016020;GO:0016021;GO:0030215","-","KOG3611-Semaphorins[T]"]
["CEBPD",293.58429,999.941162,1.768068437,0,0,"up","CEBPD","-","GO:0000978;GO:0002244;GO:0003677;GO:0003700;GO:0005634;GO:0005654;GO:0006355;GO:0006357;GO:0006366;GO:0042803;GO:0044212;GO:0045444;GO:0045669;GO:0045892;GO:0045944;GO:0046982;GO:0048839","-","KOG3119-Basic region leucine zipper transcription factor[K]"]
["CRISPLD1",10.004777,34.069912,1.76780921,{"v":7.92e-251,"d":"7.92E-251"},{"v":1.04e-249,"d":"1.04E-249"},"up","CRISPLD1","cysteine rich secretory protein LCCL domain containing 1","GO:0005576;GO:0060325","-","KOG3017-Defense-related protein containing SCP domain[S]"]
["MMP16",2.492803,8.460193,1.762921701,{"v":1.65e-107,"d":"1.65E-107"},{"v":1.16e-106,"d":"1.16E-106"},"up","MMP16","matrix metallopeptidase 16 (membrane-inserted)","GO:0001503;GO:0001958;GO:0004222;GO:0005887;GO:0006508;GO:0008233;GO:0008237;GO:0008270;GO:0016020;GO:0016021;GO:0016485;GO:0016787;GO:0030574;GO:0031012;GO:0035988;GO:0046872;GO:0048701;GO:0060348;GO:0070006;GO:0097094","-","KOG1565-Gelatinase A and related matrix metalloproteases[OW]"]
["ALMS1",4.843465,16.378721,1.757711281,0,0,"up","ALMS1","-","-","-","-"]
["PDE4DIP",34.498871,116.418831,1.754703382,0,0,"up","PDE4DIP","-","-","-","-"]
["ITGB8",6.126269,20.668829,1.754376034,0,0,"up","ITGB8","-","GO:0001573;GO:0007155;GO:0007160;GO:0007229;GO:0008305;GO:0009986;GO:0010628;GO:0010629;GO:0016020;GO:0016021;GO:0034686;GO:0038023;GO:0045766;GO:0051216;GO:1990430","K06591-ko04151 PI3K-Akt signaling pathway;ko04512 ECM-receptor interaction;ko04514 Cell adhesion molecules (CAMs);ko04810 Regulation of actin cytoskeleton;ko04510 Focal adhesion;ko05410 Hypertrophic cardiomyopathy (HCM);ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC);ko05414 Dilated cardiomyopathy (DCM)","KOG1226-Integrin beta subunit (N-terminal portion of extracellular region)[TW]"]
["COQ8A",62.001869,209.127884,1.754001826,0,0,"up","COQ8A","coenzyme Q8A","GO:0005739;GO:0006744;GO:0016301;GO:0016310;GO:0043531","-","-"]
["LZTFL1",11.918856,40.166325,1.7527407,{"v":1.16e-173,"d":"1.16E-173"},{"v":1.15e-172,"d":"1.15E-172"},"up","LZTFL1","-","-","-","-"]
["EPDR1",5.614106,18.899633,1.751230011,{"v":5.14e-113,"d":"5.14E-113"},{"v":3.75e-112,"d":"3.75E-112"},"up","EPDR1","-","GO:0005509;GO:0005576;GO:0005764;GO:0007160","-","-"]
["DYNC2LI1",4.668539,15.705241,1.750203041,{"v":5.98e-55,"d":"5.98E-55"},{"v":2.83e-54,"d":"2.83E-54"},"up","DYNC2LI1","-","GO:0005737;GO:0005813;GO:0005868;GO:0005930;GO:0007368;GO:0008569;GO:0030990;GO:0031514;GO:0035721;GO:0035735;GO:0035869;GO:0036064;GO:0045177;GO:0045504;GO:0060271;GO:1902017","-","KOG3929-Uncharacterized conserved protein[S]"]
["GFM1",25.454517,85.615532,1.749950857,0,0,"up","GFM1","-","GO:0003746;GO:0003924;GO:0005525;GO:0005739;GO:0070125","-","KOG0465-Mitochondrial elongation factor[J]"]
["IFT22",7.949125,26.605885,1.742877424,{"v":5.36e-88,"d":"5.36E-88"},{"v":3.32e-87,"d":"3.32E-87"},"up","IFT22","-","GO:0005813;GO:0005929;GO:0030992","-","KOG0079-GTP-binding protein H-ray, small G protein superfamily[R]"]
["AKR1B1L",55.673859,185.057068,1.732898247,0,0,"up","AKR1B1L","aldo-keto reductase family 1 member B1-like","-","K00011-ko00040 Pentose and glucuronate interconversions;ko00051 Fructose and mannose metabolism;ko00052 Galactose metabolism;ko00561 Glycerolipid metabolism","KOG1577-Aldo/keto reductase family proteins[R]"]
["DYSF",16.12649,53.56089,1.73174747,0,0,"up","DYSF","-","GO:0001778;GO:0005509;GO:0005543;GO:0005544;GO:0005768;GO:0005769;GO:0005770;GO:0005815;GO:0005886;GO:0006906;GO:0016020;GO:0016021;GO:0030027;GO:0030139;GO:0030315;GO:0031410;GO:0042383","-","-"]
["SOX9",21.55344,71.517014,1.730368355,{"v":2.94e-249,"d":"2.94E-249"},{"v":3.85e-248,"d":"3.85E-248"},"up","SOX9","SRY (sex determining region Y)-box 9","GO:0000122;GO:0000976;GO:0000978;GO:0000981;GO:0001158;GO:0001228;GO:0001501;GO:0001502;GO:0001503;GO:0001658;GO:0001708;GO:0001755;GO:0001837;GO:0001894;GO:0001934;GO:0002009;GO:0002053;GO:0002062;GO:0002063;GO:0002683;GO:0003170;GO:0003179;GO:0003188;GO:0003203;GO:0003413;GO:0003415;GO:0003677;GO:0003682;GO:0003700;GO:0004672;GO:0005515;GO:0005634;GO:0005654;GO:0005667;GO:0006334;GO:0006338;GO:0006351;GO:0006355;GO:0006357;GO:0006366;GO:0007010;GO:0007165;GO:0007173;GO:0007219;GO:0007283;GO:0007417;GO:0007507;GO:0008013;GO:0008284;GO:0008285;GO:0008584;GO:0010564;GO:0010628;GO:0010629;GO:0010634;GO:0014032;GO:0014036;GO:0014068;GO:0019100;GO:0019933;GO:0030154;GO:0030155;GO:0030198;GO:0030238;GO:0030279;GO:0030502;GO:0030850;GO:0030857;GO:0030858;GO:0030903;GO:0030916;GO:0031018;GO:0032331;GO:0032332;GO:0032808;GO:0032967;GO:0032991;GO:0034236;GO:0034504;GO:0035019;GO:0035326;GO:0035622;GO:0036032;GO:0042127;GO:0043066;GO:0043491;GO:0043565;GO:0044212;GO:0044390;GO:0044798;GO:0045165;GO:0045595;GO:0045662;GO:0045732;GO:0045892;GO:0045893;GO:0045944;GO:0046533;GO:0046982;GO:0048566;GO:0048709;GO:0048873;GO:0050679;GO:0050680;GO:0051216;GO:0060008;GO:0060009;GO:0060018;GO:0060041;GO:0060174;GO:0060221;GO:0060290;GO:0060350;GO:0060441;GO:0060487;GO:0060512;GO:0060517;GO:0060532;GO:0060534;GO:0060729;GO:0060784;GO:0061035;GO:0061036;GO:0061046;GO:0061138;GO:0061145;GO:0065003;GO:0070168;GO:0070371;GO:0070384;GO:0071260;GO:0071300;GO:0071347;GO:0071364;GO:0071504;GO:0071560;GO:0071599;GO:0071773;GO:0072034;GO:0072170;GO:0072189;GO:0072190;GO:0072193;GO:0072197;GO:0072289;GO:0090090;GO:0090103;GO:0090184;GO:0090190;GO:0090300;GO:0097065;GO:0097157;GO:0098609;GO:1901203;GO:1902027;GO:1902894;GO:1903011;GO:2000020;GO:2000138;GO:2000741;GO:2000794;GO:2001054","-","KOG0527-HMG-box transcription factor[K]"]
["SRD5A2",4.419173,14.655397,1.729583734,{"v":3.24e-58,"d":"3.24E-58"},{"v":1.59e-57,"d":"1.59E-57"},"up","SRD5A2","-","GO:0003865;GO:0005737;GO:0006629;GO:0006694;GO:0006702;GO:0008202;GO:0008209;GO:0008584;GO:0009917;GO:0016020;GO:0016021;GO:0016627;GO:0030283;GO:0030539;GO:0030540;GO:0042448;GO:0055114;GO:0061370","K12344-ko00140 Steroid hormone biosynthesis;ko05215 Prostate cancer","KOG1638-Steroid reductase[I]"]
["RP11-400G3.5",308.199066,1018.915344,1.725099796,0,0,"up","RP11-400G3.5","-","GO:0004497;GO:0005506;GO:0016491;GO:0016705;GO:0016712;GO:0020037;GO:0046872;GO:0055114","K07413-ko00140 Steroid hormone biosynthesis;ko00590 Arachidonic acid metabolism;ko00591 Linoleic acid metabolism;ko00830 Retinol metabolism;ko04726 Serotonergic synapse;ko04750 Inflammatory mediator regulation of TRP channels;ko05204 Chemical carcinogenesis","-"]
["S100A1",37.481525,123.587021,1.721275683,{"v":8.07e-145,"d":"8.07E-145"},{"v":7.01e-144,"d":"7.01E-144"},"up","S100A1","S100 calcium binding protein A1","GO:0005509;GO:0005634;GO:0008016;GO:0016529;GO:0042802;GO:0042803;GO:0044548;GO:0046872;GO:0051000;GO:0051117;GO:1903672","-","-"]
["PLLP",1.982302,6.518173,1.717290872,{"v":8.4e-15,"d":"8.40E-15"},{"v":2.15e-14,"d":"2.15E-14"},"up","PLLP","plasmolipin","GO:0016020;GO:0016021","-","-"]
["LOC427799",2.125881,6.988316,1.716884004,{"v":2.66e-49,"d":"2.66E-49"},{"v":1.19e-48,"d":"1.19E-48"},"up","LOC427799","-","-","-","-"]
["LOC416055",2.863755,9.413665,1.716848441,{"v":1.54e-34,"d":"1.54E-34"},{"v":5.76e-34,"d":"5.76E-34"},"up","LOC416055","-","-","-","-"]
["LOC107054950",1.672332,5.488248,1.714484388,{"v":1.3e-78,"d":"1.30E-78"},{"v":7.49e-78,"d":"7.49E-78"},"up","LOC107054950","-","-","-","-"]
["CEBPB",42.522148,139.533371,1.714323819,0,0,"up","CEBPB","CCAAT/enhancer binding protein beta","GO:0000779;GO:0000790;GO:0000977;GO:0000978;GO:0000979;GO:0000981;GO:0001046;GO:0001158;GO:0001541;GO:0003677;GO:0003682;GO:0003700;GO:0005515;GO:0005634;GO:0005654;GO:0005737;GO:0006351;GO:0006355;GO:0006366;GO:0010628;GO:0016363;GO:0019900;GO:0030182;GO:0032496;GO:0032753;GO:0034976;GO:0035035;GO:0042130;GO:0042742;GO:0042803;GO:0042826;GO:0043524;GO:0043565;GO:0044212;GO:0044389;GO:0045408;GO:0045444;GO:0045600;GO:0045669;GO:0045670;GO:0045892;GO:0045893;GO:0045944;GO:0046982;GO:0060850;GO:0070059;GO:0070169;GO:0071230;GO:0072574;GO:0090575;GO:0097421;GO:0120162;GO:1990440;GO:2000120;GO:2000144;GO:2000617","-","KOG3119-Basic region leucine zipper transcription factor[K]"]
["RFX3",3.71366,12.171693,1.712616209,{"v":3.08e-204,"d":"3.08E-204"},{"v":3.47e-203,"d":"3.47E-203"},"up","RFX3","-","GO:0000790;GO:0000978;GO:0003677;GO:0003700;GO:0005634;GO:0006351;GO:0006355;GO:0006357;GO:0007368;GO:0031018;GO:0043565;GO:0044212;GO:0045892;GO:0045893;GO:0045944;GO:0048469;GO:0050796;GO:0060271;GO:0060285;GO:0060287;GO:0072560;GO:2000078","-","-"]
["DYNLT1",5.836098,19.036671,1.705705198,{"v":3.35e-109,"d":"3.35E-109"},{"v":2.38e-108,"d":"2.38E-108"},"up","DYNLT1","-","GO:0005868;GO:0005881;GO:0019060;GO:0042802;GO:0043657;GO:0099503","-","KOG4081-Dynein light chain[N]"]
["BTBD19",4.665814,15.214836,1.705278082,{"v":3.61e-50,"d":"3.61E-50"},{"v":1.63e-49,"d":"1.63E-49"},"up","BTBD19","-","-","-","KOG4350-Uncharacterized conserved protein, contains BTB/POZ domain[R]"]
["WNK4",3.025183,9.863042,1.70501026,{"v":4.76e-91,"d":"4.76E-91"},{"v":3.01e-90,"d":"3.01E-90"},"up","WNK4","-","GO:0004672;GO:0004674;GO:0005524;GO:0005737;GO:0005923;GO:0006468;GO:0006811;GO:0006821;GO:0008104;GO:0019869;GO:0050794;GO:0050801;GO:0070294;GO:0072156;GO:0090188","-","-"]
["SLC1A1",3.473647,11.324891,1.704974108,{"v":9.57e-85,"d":"9.57E-85"},{"v":5.8e-84,"d":"5.80E-84"},"up","SLC1A1","-","GO:0005313;GO:0005314;GO:0005886;GO:0005887;GO:0010460;GO:0015108;GO:0015293;GO:0015501;GO:0015813;GO:0016020;GO:0016021;GO:0016324;GO:0033229;GO:0042883;GO:0051260;GO:0051938;GO:0070779;GO:0098712;GO:0140009;GO:1902476;GO:1903712","-","KOG3787-Glutamate/aspartate and neutral amino acid transporters[E]"]
["AMPD3",6.026356,19.619532,1.702932822,{"v":2.22e-254,"d":"2.22E-254"},{"v":2.95e-253,"d":"2.95E-253"},"up","AMPD3","adenosine monophosphate deaminase 3","GO:0003876;GO:0006188;GO:0009168;GO:0016787;GO:0019239;GO:0032264;GO:0034101;GO:0046031;GO:0046033;GO:0046034;GO:0046039;GO:0046872;GO:0097009","K01490-ko00230 Purine metabolism","KOG1096-Adenosine monophosphate deaminase[F]"]
["CTNNAL1",9.506907,30.91897,1.701444307,{"v":2.32e-241,"d":"2.32E-241"},{"v":2.96e-240,"d":"2.96E-240"},"up","CTNNAL1","-","GO:0005829;GO:0007155;GO:0007266;GO:0045296;GO:0051015","-","KOG3681-Alpha-catenin[W]"]
["FGFR4",13.574948,43.998024,1.696492061,{"v":7.27e-246,"d":"7.27E-246"},{"v":9.41e-245,"d":"9.41E-245"},"up","FGFR4","-","GO:0000166;GO:0004672;GO:0004713;GO:0004714;GO:0005007;GO:0005524;GO:0005783;GO:0005794;GO:0005886;GO:0005887;GO:0005911;GO:0006468;GO:0008201;GO:0008284;GO:0008543;GO:0010628;GO:0010715;GO:0016020;GO:0016021;GO:0016301;GO:0016310;GO:0016477;GO:0016740;GO:0017134;GO:0018108;GO:0030133;GO:0043085;GO:0045862;GO:0046777;GO:0070374;GO:0070857;GO:2000573","K05095-ko04014 Ras signaling pathway;ko04015 Rap1 signaling pathway;ko04010 MAPK signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04144 Endocytosis;ko04810 Regulation of actin cytoskeleton;ko04550 Signaling pathways regulating pluripotency of stem cells","KOG0200-Fibroblast/platelet-derived growth factor receptor and related receptor tyrosine kinases[T]"]
["GFCBPL",28.215128,91.32093,1.694476657,{"v":8.34e-131,"d":"8.34E-131"},{"v":6.73e-130,"d":"6.73E-130"},"up","GFCBPL","-","-","-","-"]
["CYP2C45",331.846313,1073.268799,1.693424292,0,0,"up","CYP2C45","cytochrome P-450 2C45","GO:0004497;GO:0005506;GO:0016491;GO:0016705;GO:0016712;GO:0019825;GO:0020037;GO:0046872;GO:0055114","K07413-ko00140 Steroid hormone biosynthesis;ko00590 Arachidonic acid metabolism;ko00591 Linoleic acid metabolism;ko00830 Retinol metabolism;ko04726 Serotonergic synapse;ko04750 Inflammatory mediator regulation of TRP channels;ko05204 Chemical carcinogenesis","-"]
["IFT140",4.776443,15.334983,1.682818014,{"v":2.22e-153,"d":"2.22E-153"},{"v":2e-152,"d":"2.00E-152"},"up","IFT140","intraflagellar transport 140","GO:0001750;GO:0005813;GO:0005929;GO:0005930;GO:0007368;GO:0007507;GO:0008589;GO:0021532;GO:0030991;GO:0031076;GO:0032391;GO:0035108;GO:0035721;GO:0035845;GO:0036064;GO:0042073;GO:0042733;GO:0048701;GO:0048705;GO:0060041;GO:0060271;GO:0061512;GO:0072001;GO:0097730;GO:1902017;GO:1905515;GO:1990403","-","KOG3617-WD40 and TPR repeat-containing protein[R]"]
["SLC38A3",10.583654,33.938381,1.681079941,{"v":6.52e-190,"d":"6.52E-190"},{"v":6.86e-189,"d":"6.86E-189"},"up","SLC38A3","-","GO:0005290;GO:0005886;GO:0005887;GO:0006867;GO:0006868;GO:0015180;GO:0015182;GO:0015186;GO:0015808;GO:0015817;GO:0016020;GO:0016021;GO:0051365;GO:0061402;GO:0089709","-","KOG1305-Amino acid transporter protein[E]"]
["PLAGL2",2.592407,8.309158,1.680410056,{"v":4.58e-186,"d":"4.58E-186"},{"v":4.74e-185,"d":"4.74E-185"},"up","PLAGL2","-","GO:0000981;GO:0003676;GO:0005634;GO:0006366;GO:0006629;GO:0006915;GO:0009791;GO:0034378;GO:0043565;GO:0045944;GO:2001244","-","KOG3608-Zn finger proteins[R]"]
["IQCK",6.359731,20.381935,1.680253373,{"v":1.45e-76,"d":"1.45E-76"},{"v":8.24e-76,"d":"8.24E-76"},"up","IQCK","-","-","-","-"]
["H2AFY2",1.783437,5.709725,1.678761009,{"v":1.49e-15,"d":"1.49E-15"},{"v":3.9e-15,"d":"3.90E-15"},"up","H2AFY2","H2A histone family, member Y2","GO:0000122;GO:0000786;GO:0000790;GO:0000977;GO:0003677;GO:0005634;GO:0005654;GO:0005694;GO:0006325;GO:0006334;GO:0006342;GO:0007420;GO:0007549;GO:0016020;GO:0016021;GO:0031490;GO:0035098;GO:0044212;GO:0045618;GO:0045814;GO:0046982;GO:0071169;GO:1901837","K11251-ko05322 Systemic lupus erythematosus;ko05034 Alcoholism","KOG1756-Histone 2A[B]"]
["C3orf33",3.169039,10.136057,1.677379223,{"v":5.36e-26,"d":"5.36E-26"},{"v":1.75e-25,"d":"1.75E-25"},"up","C3orf33","-","GO:0005615;GO:0051090;GO:0070373","-","-"]
["SDK2",2.482466,7.93529,1.67650899,{"v":9.12e-146,"d":"9.12E-146"},{"v":7.94e-145,"d":"7.94E-145"},"up","SDK2","sidekick cell adhesion molecule 2","GO:0005886;GO:0007155;GO:0007156;GO:0007416;GO:0010842;GO:0016020;GO:0016021;GO:0030054;GO:0042802;GO:0045202;GO:0060219","-","KOG3513-Neural cell adhesion molecule L1[T]"]
["RTN2",9.182235,29.306482,1.674302534,{"v":1.34e-63,"d":"1.34E-63"},{"v":6.85e-63,"d":"6.85E-63"},"up","RTN2","-","-","-","-"]
["CBS",10.796942,34.41201,1.672289404,0,0,"up","CBS","-","GO:0001958;GO:0001974;GO:0004122;GO:0005737;GO:0006535;GO:0006801;GO:0008652;GO:0010749;GO:0016829;GO:0019343;GO:0019344;GO:0020037;GO:0021587;GO:0030170;GO:0043506;GO:0050667;GO:0050880;GO:0051593;GO:0060351","K01697-ko01230 Biosynthesis of amino acids;ko00260 Glycine, serine and threonine metabolism;ko00270 Cysteine and methionine metabolism","-"]
["BBS7",8.047024,25.624594,1.671001906,{"v":1.45e-138,"d":"1.45E-138"},{"v":1.21e-137,"d":"1.21E-137"},"up","BBS7","-","GO:0001103;GO:0001654;GO:0001750;GO:0005634;GO:0005813;GO:0005930;GO:0006357;GO:0007224;GO:0007420;GO:0007507;GO:0008104;GO:0016020;GO:0032436;GO:0034464;GO:0036064;GO:0045444;GO:0046907;GO:0060173;GO:0060271;GO:1903929","-","-"]
["SLC4A1",4.853283,15.451008,1.670668068,{"v":2.16e-103,"d":"2.16E-103"},{"v":1.48e-102,"d":"1.48E-102"},"up","SLC4A1","solute carrier family 4 member 1 (Diego blood group)","GO:0005452;GO:0005886;GO:0005887;GO:0006811;GO:0006820;GO:0008509;GO:0008510;GO:0015106;GO:0015301;GO:0015698;GO:0015701;GO:0016020;GO:0016021;GO:0016323;GO:0051453;GO:0098656","-","KOG1172-Na+-independent Cl/HCO3 exchanger AE1 and related transporters (SLC4 family)[P]"]
["FKBP3",185.202484,588.238525,1.667297824,0,0,"up","FKBP3","FK506 binding protein 3","GO:0000413;GO:0003755;GO:0005634;GO:0016853","-","KOG0544-FKBP-type peptidyl-prolyl cis-trans isomerase[O]"]
["CCDC85C",2.058084,6.521109,1.663815468,{"v":2.24e-72,"d":"2.24E-72"},{"v":1.23e-71,"d":"1.23E-71"},"up","CCDC85C","-","-","-","KOG3819-Uncharacterized conserved proteins (Hepatitis delta antigen-interacting protein A)[S]"]
["CCDC28B",2.854964,9.030833,1.661386514,{"v":1.8e-19,"d":"1.80E-19"},{"v":5.16e-19,"d":"5.16E-19"},"up","CCDC28B","coiled-coil domain containing 28B","GO:0005813;GO:0060271","-","-"]
["ABI3",1.967433,6.220946,1.660819477,{"v":5.48e-64,"d":"5.48E-64"},{"v":2.81e-63,"d":"2.81E-63"},"up","ABI3","-","GO:0005622;GO:0005737;GO:0030027;GO:0030334;GO:0042802","-","KOG2546-Abl interactor ABI-1, contains SH3 domain[TZ]"]
["APOLD1",4.529567,14.318841,1.660469673,{"v":1.98e-78,"d":"1.98E-78"},{"v":1.14e-77,"d":"1.14E-77"},"up","APOLD1","-","GO:0005576;GO:0005654;GO:0005829;GO:0006869;GO:0008289;GO:0016020;GO:0016021;GO:0042157","-","-"]
["CYCS",94.253494,297.707672,1.659278395,0,0,"up","CYCS","cytochrome c, somatic","-","K08738-ko00920 Sulfur metabolism;ko02020 Two-component system;ko04210 Apoptosis;ko04214 Apoptosis - fly;ko04215 Apoptosis - multiple species;ko04115 p53 signaling pathway;ko05200 Pathways in cancer;ko05210 Colorectal cancer;ko05222 Small cell lung cancer;ko05010 Alzheimer's disease;ko05012 Parkinson's disease;ko05014 Amyotrophic lateral sclerosis (ALS);ko05016 Huntington's disease;ko05416 Viral myocarditis;ko04932 Non-alcoholic fatty liver disease (NAFLD);ko05134 Legionellosis;ko05152 Tuberculosis;ko05164 Influenza A;ko05161 Hepatitis B;ko05168 Herpes simplex infection;ko05145 Toxoplasmosis;ko01524 Platinum drug resistance","KOG3453-Cytochrome c[C]"]
["LRRC20",18.50231,58.389786,1.658010622,{"v":5.75e-85,"d":"5.75E-85"},{"v":3.49e-84,"d":"3.49E-84"},"up","LRRC20","leucine rich repeat containing 20","-","-","KOG4579-Leucine-rich repeat (LRR) protein associated with apoptosis in muscle tissue[R]"]
["NNT",29.488617,93.042229,1.657727497,0,0,"up","NNT","-","GO:0005739;GO:0005743;GO:0006740;GO:0008746;GO:0008750;GO:0016020;GO:0016021;GO:0016491;GO:0050661;GO:0051287;GO:0055114;GO:0072593;GO:1902600","K00323-ko00760 Nicotinate and nicotinamide metabolism","-"]
["PKNOX2",7.802743,24.618378,1.657682424,{"v":2.29e-170,"d":"2.29E-170"},{"v":2.24e-169,"d":"2.24E-169"},"up","PKNOX2","PBX/knotted 1 homeobox 2","-","-","KOG0773-Transcription factor MEIS1 and related HOX domain proteins[K]"]
["LOC112531294",5.867713,18.489145,1.655808298,{"v":3.19e-41,"d":"3.19E-41"},{"v":1.31e-40,"d":"1.31E-40"},"up","LOC112531294","-","-","-","-"]
["GAPDH",3435.184814,10808.86719,1.653755707,0,0,"up","GAPDH","glyceraldehyde-3-phosphate dehydrogenase","GO:0000226;GO:0000740;GO:0004365;GO:0005634;GO:0005737;GO:0005811;GO:0005829;GO:0005856;GO:0005886;GO:0006006;GO:0006094;GO:0006096;GO:0006915;GO:0008017;GO:0010951;GO:0015630;GO:0016020;GO:0016491;GO:0016620;GO:0016740;GO:0017148;GO:0019828;GO:0031640;GO:0031965;GO:0035605;GO:0035606;GO:0042802;GO:0043066;GO:0043231;GO:0050661;GO:0050715;GO:0050821;GO:0050832;GO:0051287;GO:0051402;GO:0051873;GO:0052501;GO:0055114;GO:0061844;GO:0071346;GO:0097452;GO:0097718;GO:1990904;GO:0004365;GO:0006006;GO:0006096;GO:0016020;GO:0016491;GO:0016620;GO:0050661;GO:0051287;GO:0055114","K00134-ko01200 Carbon metabolism;ko01230 Biosynthesis of amino acids;ko00010 Glycolysis / Gluconeogenesis;ko00710 Carbon fixation in photosynthetic organisms;ko04066 HIF-1 signaling pathway;ko05010 Alzheimer's disease","KOG0657-Glyceraldehyde 3-phosphate dehydrogenase[G]"]
["CEP162",4.01767,12.632319,1.652688534,{"v":1.82e-150,"d":"1.82E-150"},{"v":1.62e-149,"d":"1.62E-149"},"up","CEP162","-","GO:0005813;GO:0005814;GO:0005879;GO:0060271","-","-"]
["METTL23",1.822874,5.718584,1.649443117,{"v":3.63e-30,"d":"3.63E-30"},{"v":1.27e-29,"d":"1.27E-29"},"up","METTL23","-","-","-","KOG2793-Putative N2,N2-dimethylguanosine tRNA methyltransferase[A]"]
["HBBA",408.122742,1279.559204,1.648571891,0,0,"up","HBBA","hemoglobin beta, subunit A","-","-","-"]
["SH3BP5",33.445992,104.777023,1.647417136,0,0,"up","SH3BP5","SH3 domain binding protein 5","GO:0004860;GO:0005622;GO:0005654;GO:0006469;GO:0016604;GO:0035556","-","KOG2008-BTK-associated SH3-domain binding protein SAB[T]"]
["LOC112531626",5.332585,16.701803,1.647096891,{"v":1.36e-05,"d":"1.36E-05"},{"v":2.41e-05,"d":"2.41E-05"},"up","LOC112531626","-","-","-","-"]
["RAB18L",7.609177,23.813158,1.64594663,{"v":1.98e-130,"d":"1.98E-130"},{"v":1.59e-129,"d":"1.59E-129"},"up","RAB18L","-","GO:0003924;GO:0005525","-","-"]
["DYNC2H1",2.410005,7.539292,1.64539291,{"v":2.12e-201,"d":"2.12E-201"},{"v":2.36e-200,"d":"2.36E-200"},"up","DYNC2H1","-","GO:0003777;GO:0005524;GO:0005930;GO:0007018;GO:0007368;GO:0007507;GO:0009953;GO:0016485;GO:0016887;GO:0021522;GO:0030182;GO:0030286;GO:0030326;GO:0030900;GO:0031514;GO:0035721;GO:0045177;GO:0045880;GO:0060271;GO:0060976;GO:0061512;GO:1905515","K10414-ko04145 Phagosome;ko04962 Vasopressin-regulated water reabsorption;ko05132 Salmonella infection","KOG3595-Dyneins, heavy chain[Z]"]
["LOC112531638",2.9834,9.332098,1.645244037,{"v":1.25e-05,"d":"1.25E-05"},{"v":2.21e-05,"d":"2.21E-05"},"up","LOC112531638","-","-","-","-"]
["LOC107050456",20.496025,64.076233,1.644445195,0,0,"up","LOC107050456","-","-","K00693-ko00500 Starch and sucrose metabolism;ko04151 PI3K-Akt signaling pathway;ko04152 AMPK signaling pathway;ko04910 Insulin signaling pathway;ko04922 Glucagon signaling pathway;ko04931 Insulin resistance","-"]
["PDLIM5",67.624184,210.762344,1.640005944,{"v":2.2e-73,"d":"2.20E-73"},{"v":1.22e-72,"d":"1.22E-72"},"up","PDLIM5","PDZ and LIM domain 5","GO:0015629;GO:0046872","-","KOG1703-Adaptor protein Enigma and related PDZ-LIM proteins[TZ]"]
["LOC420807",3.801143,11.835238,1.638583512,{"v":6.64e-32,"d":"6.64E-32"},{"v":2.39e-31,"d":"2.39E-31"},"up","LOC420807","-","GO:0008152;GO:0016491;GO:0016616;GO:0051287;GO:0055114","-","-"]
["SOD3",50.317493,156.512283,1.637143935,0,0,"up","SOD3","-","GO:0001666;GO:0004784;GO:0005507;GO:0005615;GO:0005737;GO:0006801;GO:0008270;GO:0016491;GO:0019430;GO:0046872;GO:0055114;GO:0062023","-","KOG0441-Cu2+/Zn2+ superoxide dismutase SOD1[P]"]
["CHCHD7",12.103083,37.551182,1.63348373,0,0,"up","CHCHD7","-","-","-","-"]
["PDE10A",7.665072,23.734007,1.630584442,0,0,"up","PDE10A","-","GO:0004114;GO:0004118;GO:0007165;GO:0008081;GO:0010738;GO:0016787;GO:0030552;GO:0043949;GO:0046872","K18438-ko00230 Purine metabolism;ko05032 Morphine addiction","KOG3689-Cyclic nucleotide phosphodiesterase[T]"]
["CRY1",46.340061,143.392365,1.629636361,0,0,"up","CRY1","cryptochrome circadian clock 1","GO:0000122;GO:0000166;GO:0003690;GO:0005634;GO:0005737;GO:0005739;GO:0005829;GO:0006094;GO:0006351;GO:0006355;GO:0006975;GO:0007623;GO:0008134;GO:0009881;GO:0018298;GO:0019900;GO:0019901;GO:0019902;GO:0019915;GO:0031397;GO:0032868;GO:0032922;GO:0033762;GO:0035257;GO:0042593;GO:0042622;GO:0042752;GO:0042754;GO:0042826;GO:0043153;GO:0045744;GO:0045892;GO:0048511;GO:0050896;GO:0070888;GO:0097381;GO:2000001;GO:2000323;GO:2000850","-","KOG0133-Deoxyribodipyrimidine photolyase/cryptochrome[LT]"]
["ADGRG1",15.913538,49.226715,1.629186848,{"v":1.11e-263,"d":"1.11E-263"},{"v":1.52e-262,"d":"1.52E-262"},"up","ADGRG1","-","GO:0001525;GO:0004888;GO:0004930;GO:0005518;GO:0005622;GO:0007155;GO:0007166;GO:0007186;GO:0007266;GO:0007420;GO:0008201;GO:0008285;GO:0010573;GO:0016020;GO:0016021;GO:0016477;GO:0021796;GO:0021801;GO:0021819;GO:0035025;GO:0045785;GO:0050840;GO:0070528;GO:0072520;GO:0097451;GO:2000179;GO:2001223","-","KOG4193-G protein-coupled receptors[T]"]
["DUPD1",2.253166,6.968136,1.628819175,{"v":6.1e-12,"d":"6.10E-12"},{"v":1.44e-11,"d":"1.44E-11"},"up","DUPD1","dual specificity phosphatase and pro isomerase domain containing 1","GO:0004721;GO:0004725;GO:0005737;GO:0006470;GO:0008138;GO:0016311;GO:0016787;GO:0016791;GO:0032991;GO:0035335;GO:0042803","-","KOG1716-Dual specificity phosphatase[V]"]
["UNC119",3.756965,11.614864,1.628332681,{"v":2.05e-119,"d":"2.05E-119"},{"v":1.55e-118,"d":"1.55E-118"},"up","UNC119","-","GO:0000281;GO:0000922;GO:0005622;GO:0005813;GO:0007399;GO:0008289;GO:0030182;GO:0042953;GO:0045171;GO:0051233;GO:0061098","-","KOG4037-Photoreceptor synaptic vesicle protein HRG4/UNC-119[UT]"]
["GOT1",75.107483,232.081619,1.627603708,0,0,"up","GOT1","glutamic-oxaloacetic transaminase 1","GO:0003824;GO:0004069;GO:0004609;GO:0005654;GO:0005737;GO:0005739;GO:0005829;GO:0006094;GO:0006103;GO:0006107;GO:0006114;GO:0006520;GO:0006531;GO:0006532;GO:0006533;GO:0006536;GO:0007219;GO:0008483;GO:0008652;GO:0009058;GO:0016740;GO:0019550;GO:0019551;GO:0030170;GO:0032869;GO:0047801;GO:0051384;GO:0055089","K14454-ko01200 Carbon metabolism;ko01210 2-Oxocarboxylic acid metabolism;ko01230 Biosynthesis of amino acids;ko00710 Carbon fixation in photosynthetic organisms;ko00250 Alanine, aspartate and glutamate metabolism;ko00270 Cysteine and methionine metabolism;ko00220 Arginine biosynthesis;ko00330 Arginine and proline metabolism;ko00350 Tyrosine metabolism;ko00360 Phenylalanine metabolism;ko00400 Phenylalanine, tyrosine and tryptophan biosynthesis;ko00950 Isoquinoline alkaloid biosynthesis;ko00960 Tropane, piperidine and pyridine alkaloid biosynthesis","KOG1412-Aspartate aminotransferase/Glutamic oxaloacetic transaminase AAT2/GOT1[E]"]
["UQCR11",123.509399,381.267334,1.626182096,0,0,"up","UQCR11","ubiquinol-cytochrome c reductase, complex III subunit XI","GO:0005739;GO:0005743;GO:0008121;GO:0009055;GO:0022900","K00420-ko00190 Oxidative phosphorylation;ko04260 Cardiac muscle contraction;ko05010 Alzheimer's disease;ko05012 Parkinson's disease;ko05016 Huntington's disease;ko04932 Non-alcoholic fatty liver disease (NAFLD)","-"]
["MIEF2",4.127903,12.726367,1.624339656,{"v":6.02e-69,"d":"6.02E-69"},{"v":3.23e-68,"d":"3.23E-68"},"up","MIEF2","-","GO:0005739;GO:0005741;GO:0007005;GO:0032464;GO:0090141;GO:0090314","-","-"]
["HIPK2",32.164696,99.097816,1.623375209,0,0,"up","HIPK2","-","GO:0000122;GO:0001102;GO:0001934;GO:0003713;GO:0003714;GO:0004672;GO:0004674;GO:0005524;GO:0005634;GO:0005737;GO:0006468;GO:0006978;GO:0007179;GO:0007224;GO:0007628;GO:0008284;GO:0008344;GO:0009952;GO:0010842;GO:0016604;GO:0016605;GO:0018105;GO:0018107;GO:0030182;GO:0030511;GO:0030514;GO:0032092;GO:0042771;GO:0043388;GO:0043524;GO:0045766;GO:0045893;GO:0045944;GO:0046330;GO:0046332;GO:0046790;GO:0048596;GO:0050882;GO:0051091;GO:0060059;GO:0060235;GO:0060395;GO:0061072;GO:0090575;GO:2000059","-","KOG0667-Dual-specificity tyrosine-phosphorylation regulated kinase[R]"]
["IL16",2.388345,7.354836,1.622681921,{"v":2.09e-69,"d":"2.09E-69"},{"v":1.13e-68,"d":"1.13E-68"},"up","IL16","interleukin 16","GO:0005125;GO:0005576;GO:0005615;GO:0005622;GO:0005634;GO:0005737;GO:0005829;GO:0005886;GO:0006935;GO:0010469;GO:0016607;GO:0030595;GO:0042609;GO:0050930;GO:0051924","-","KOG3209-WW domain-containing protein[R]"]
["RHPN1",7.278475,22.38204,1.620633425,{"v":3.78e-183,"d":"3.78E-183"},{"v":3.88e-182,"d":"3.88E-182"},"up","RHPN1","-","GO:0007165","-","KOG2220-Predicted signal transduction protein[R]"]
["FRY",7.599557,23.36787,1.62053901,0,0,"up","FRY","-","GO:0000902;GO:0004857;GO:0005938;GO:0030427;GO:0031175;GO:0043086;GO:0090527;GO:1904428","-","KOG1825-Fry-like conserved proteins[R]"]
["GPRC5A",10.199157,31.339336,1.6195247,{"v":1.56e-153,"d":"1.56E-153"},{"v":1.41e-152,"d":"1.41E-152"},"up","GPRC5A","-","-","-","-"]
["TMEM98",6.246349,19.171074,1.617846078,{"v":3.34e-72,"d":"3.34E-72"},{"v":1.83e-71,"d":"1.83E-71"},"up","TMEM98","-","GO:0005783;GO:0016020;GO:0016021","-","-"]
["PLEKHG1",3.259068,9.970653,1.613228539,{"v":8.82e-144,"d":"8.82E-144"},{"v":7.61e-143,"d":"7.61E-143"},"up","PLEKHG1","-","GO:0005089;GO:0005634;GO:0005654;GO:0035023","-","KOG3518-Putative guanine nucleotide exchange factor[R]"]
["METTL7A",36.721275,112.255424,1.612097099,{"v":1.36e-232,"d":"1.36E-232"},{"v":1.69e-231,"d":"1.69E-231"},"up","METTL7A","-","GO:0008152;GO:0008168;GO:0016020;GO:0016021;GO:0032259","-","KOG4300-Predicted methyltransferase[R]"]
["IFT43",8.964943,27.397533,1.611679677,{"v":6.73e-45,"d":"6.73E-45"},{"v":2.88e-44,"d":"2.88E-44"},"up","IFT43","-","GO:0005815;GO:0005929;GO:0015630;GO:0030991;GO:0035721;GO:0060271","-","-"]
["C1H21ORF59",25.683561,78.258507,1.607402343,{"v":3.29e-186,"d":"3.29E-186"},{"v":3.41e-185,"d":"3.41E-185"},"up","C1H21ORF59","chromosome 1 open reading frame, human C21orf59","GO:0048858","-","-"]
["TMEM117",2.023299,6.163143,1.606956731,{"v":8.01e-87,"d":"8.01E-87"},{"v":4.91e-86,"d":"4.91E-86"},"up","TMEM117","-","-","-","-"]
["SORL1",5.550632,16.899187,1.606229889,{"v":7.53e-290,"d":"7.53E-290"},{"v":1.1e-288,"d":"1.10E-288"},"up","SORL1","sortilin related receptor 1","GO:0001540;GO:0005615;GO:0005641;GO:0005768;GO:0005769;GO:0005783;GO:0005794;GO:0005802;GO:0006605;GO:0006622;GO:0006629;GO:0006869;GO:0006892;GO:0006897;GO:0008202;GO:0008203;GO:0014910;GO:0016020;GO:0016021;GO:0030169;GO:0030306;GO:0031985;GO:0032091;GO:0032460;GO:0034067;GO:0034362;GO:0043407;GO:0045053;GO:0045732;GO:0050768;GO:0051604;GO:0055037;GO:0070863;GO:1901215;GO:1902430;GO:1902771;GO:1902948;GO:1902953;GO:1902955;GO:1902960;GO:1902963;GO:1902966;GO:1902997;GO:2001137","-","KOG3511-Sortilin and related receptors[R]"]
["TXNDC15",5.780738,17.579695,1.604584449,{"v":1.44e-107,"d":"1.44E-107"},{"v":1.01e-106,"d":"1.01E-106"},"up","TXNDC15","-","GO:0016020;GO:0016021","-","KOG0907-Thioredoxin[O]"]
["NFIL3",34.541958,104.973427,1.603602401,0,0,"up","NFIL3","nuclear factor, interleukin 3 regulated","GO:0000122;GO:0003677;GO:0003700;GO:0005634;GO:0005737;GO:0006351;GO:0006355;GO:0006366;GO:0006955;GO:0007623;GO:0048511;GO:0000122;GO:0000977;GO:0000978;GO:0003700;GO:0005634;GO:0006351;GO:0006355;GO:0006366;GO:0006955;GO:0007623;GO:0010628;GO:0071353","-","KOG3119-Basic region leucine zipper transcription factor[K]"]
["RAB20",11.745573,35.689083,1.603365737,{"v":3.08e-97,"d":"3.08E-97"},{"v":2.03e-96,"d":"2.03E-96"},"up","RAB20","-","GO:0003924;GO:0005525;GO:0005769;GO:0005794;GO:0005886;GO:0030100;GO:0030139;GO:0043231;GO:0045335;GO:0071346;GO:0090383;GO:0090385","-","KOG0092-GTPase Rab5/YPT51 and related small G protein superfamily GTPases[U]"]
["RCSD1",12.432576,37.629417,1.597735687,{"v":5.11e-241,"d":"5.11E-241"},{"v":6.51e-240,"d":"6.51E-240"},"up","RCSD1","RCSD domain containing 1","GO:0051015;GO:0071474","-","-"]
["HBM",165.964539,502.094513,1.59708394,0,0,"up","HBM","hemoglobin subunit mu","GO:0005344;GO:0005833;GO:0015671;GO:0019825;GO:0020037;GO:0046872","-","-"]
["BBOX1",13.237623,39.917984,1.592394772,{"v":3.06e-240,"d":"3.06E-240"},{"v":3.9e-239,"d":"3.90E-239"},"up","BBOX1","-","GO:0005506;GO:0008270;GO:0008336;GO:0016491;GO:0042802;GO:0045329;GO:0055114","K00471-ko00310 Lysine degradation","KOG3888-Gamma-butyrobetaine,2-oxoglutarate dioxygenase[I]"]
["F8",2.98443,8.99934,1.592363784,{"v":2.48e-116,"d":"2.48E-116"},{"v":1.85e-115,"d":"1.85E-115"},"up","F8","-","GO:0005507;GO:0016491;GO:0030168;GO:0046872;GO:0055114","-","KOG1094-Discoidin domain receptor DDR1[T]"]
["DNAL1",4.02777,12.126877,1.590154857,{"v":1.68e-146,"d":"1.68E-146"},{"v":1.47e-145,"d":"1.47E-145"},"up","DNAL1","dynein axonemal light chain 1","GO:0036158;GO:0043014;GO:0045504","-","KOG1859-Leucine-rich repeat proteins[R]"]
["CCDC17",10.206186,30.712757,1.589394186,{"v":1.17e-128,"d":"1.17E-128"},{"v":9.32e-128,"d":"9.32E-128"},"up","CCDC17","-","-","-","-"]
["SLC4A3",4.862349,14.586305,1.584889113,{"v":2.23e-155,"d":"2.23E-155"},{"v":2.03e-154,"d":"2.03E-154"},"up","SLC4A3","-","GO:0005452;GO:0005886;GO:0005887;GO:0006811;GO:0006820;GO:0008509;GO:0008510;GO:0015301;GO:0015698;GO:0015701;GO:0016020;GO:0016021;GO:0051453;GO:0098656","-","KOG1172-Na+-independent Cl/HCO3 exchanger AE1 and related transporters (SLC4 family)[P]"]
["OSCP1",4.505509,13.463851,1.57932911,{"v":1.96e-38,"d":"1.96E-38"},{"v":7.73e-38,"d":"7.73E-38"},"up","OSCP1","-","GO:0003674;GO:0005575;GO:0008150","-","KOG4033-Uncharacterized conserved protein[S]"]
["LIN7A",3.090681,9.233894,1.579014415,{"v":4e-48,"d":"4.00E-48"},{"v":1.77e-47,"d":"1.77E-47"},"up","LIN7A","-","GO:0005622;GO:0005886;GO:0005911;GO:0006887;GO:0007269;GO:0015031;GO:0016020;GO:0016323;GO:0030054;GO:0045199;GO:0045202;GO:0048489;GO:0048839;GO:0097016;GO:0097025;GO:0098793;GO:1903361","-","KOG3550-Receptor targeting protein Lin-7[W]"]
["CA8",5.215779,15.561774,1.577051886,{"v":2.76e-100,"d":"2.76E-100"},{"v":1.86e-99,"d":"1.86E-99"},"up","CA8","-","GO:0004089;GO:0005737;GO:0008270;GO:0046872;GO:0048015","K01672-ko00910 Nitrogen metabolism","KOG0382-Carbonic anhydrase[R]"]
["HIST1H4B",8.160151,24.344442,1.576924679,{"v":1.02e-21,"d":"1.02E-21"},{"v":3.06e-21,"d":"3.06E-21"},"up","HIST1H4B","-","-","-","-"]
["LOC424918",34.966068,104.311256,1.576867368,0,0,"up","LOC424918","-","-","-","-"]
["P2RY2",18.312481,54.615501,1.576483213,0,0,"up","P2RY2","-","-","K04269-ko04080 Neuroactive ligand-receptor interaction;ko04750 Inflammatory mediator regulation of TRP channels","-"]
["WDPCP",1.710726,5.099636,1.575785567,{"v":1.38e-32,"d":"1.38E-32"},{"v":5.03e-32,"d":"5.03E-32"},"up","WDPCP","-","GO:0001822;GO:0002093;GO:0007224;GO:0007399;GO:0010762;GO:0042733;GO:0043010;GO:0044782;GO:0045184;GO:0048568;GO:0051893;GO:0055123;GO:0060021;GO:0060271;GO:0060541;GO:0072358;GO:0090521;GO:0097541;GO:1900027;GO:2000114","-","-"]
["TCF15",11.71322,34.913097,1.575630607,{"v":8.21e-67,"d":"8.21E-67"},{"v":4.31e-66,"d":"4.31E-66"},"up","TCF15","transcription factor 15 (basic helix-loop-helix)","GO:0003677;GO:0005634;GO:0006351;GO:0006355;GO:0007275;GO:0046983;GO:0000978;GO:0001756;GO:0003016;GO:0006366;GO:0007517;GO:0009952;GO:0010468;GO:0036342;GO:0042755;GO:0043583;GO:0043588;GO:0045198;GO:0045944;GO:0046983;GO:0048339;GO:0048644;GO:0048705;GO:0050884;GO:0060231;GO:0090575;GO:1903053","-","KOG4029-Transcription factor HAND2/Transcription factor TAL1/TAL2/LYL1[K]"]
["IL15",39.133923,116.617332,1.575290576,{"v":3.24e-150,"d":"3.24E-150"},{"v":2.88e-149,"d":"2.88E-149"},"up","IL15","interleukin 15","GO:0001779;GO:0001866;GO:0005125;GO:0005126;GO:0005576;GO:0005615;GO:0005654;GO:0005737;GO:0005829;GO:0006955;GO:0007260;GO:0010469;GO:0016607;GO:0032740;GO:0032819;GO:0032825;GO:0035723;GO:0042102;GO:0045062;GO:0045580;GO:0048469;GO:0048535;GO:0050691;GO:0050778;GO:0120163;GO:1904100","K05433-ko04630 Jak-STAT signaling pathway;ko04668 TNF signaling pathway;ko04060 Cytokine-cytokine receptor interaction;ko04672 Intestinal immune network for IgA production;ko05323 Rheumatoid arthritis;ko05166 HTLV-I infection;ko05168 Herpes simplex infection","-"]
["TMEM52",17.648083,52.53154,1.573672398,0,0,"up","TMEM52","-","GO:0016020;GO:0016021","-","-"]
["TLL1",4.407386,13.116986,1.573441099,{"v":1.5e-181,"d":"1.50E-181"},{"v":1.53e-180,"d":"1.53E-180"},"up","TLL1","tolloid-like 1","GO:0004222;GO:0005509;GO:0005576;GO:0006508;GO:0007275;GO:0008233;GO:0008237;GO:0008270;GO:0016787;GO:0030154;GO:0046872","-","KOG3714-Meprin A metalloprotease[O]"]
["PIBPPDD4L",2.708379,8.037078,1.569241445,{"v":1.57e-60,"d":"1.57E-60"},{"v":7.84e-60,"d":"7.84E-60"},"up","PIBPPDD4L","-","GO:0004435;GO:0005622;GO:0006629;GO:0007165;GO:0008081;GO:0016042;GO:0016787;GO:0035556","-","-"]
["ADGRG2",4.988574,14.782019,1.567143953,{"v":2.29e-171,"d":"2.29E-171"},{"v":2.24e-170,"d":"2.24E-170"},"up","ADGRG2","-","GO:0004888;GO:0004930;GO:0005829;GO:0005886;GO:0007166;GO:0007186;GO:0016020;GO:0016021","-","KOG4193-G protein-coupled receptors[T]"]
["DGKD",7.825543,23.181303,1.566698895,0,0,"up","DGKD","-","GO:0000166;GO:0003951;GO:0004143;GO:0005524;GO:0005622;GO:0005737;GO:0005829;GO:0005886;GO:0007165;GO:0007205;GO:0008152;GO:0010033;GO:0016301;GO:0016310;GO:0016740;GO:0035556;GO:0042803;GO:0046982;GO:0051260","K00901-ko00561 Glycerolipid metabolism;ko00564 Glycerophospholipid metabolism;ko04070 Phosphatidylinositol signaling system;ko04072 Phospholipase D signaling pathway;ko05231 Choline metabolism in cancer","KOG1170-Diacylglycerol kinase[I]"]
["SYTL3",2.473582,7.317756,1.564799586,{"v":4.54e-68,"d":"4.54E-68"},{"v":2.41e-67,"d":"2.41E-67"},"up","SYTL3","-","GO:0005509;GO:0005543;GO:0005544;GO:0005886;GO:0006887;GO:0006906;GO:0016020;GO:0017137;GO:0017158;GO:0019897;GO:0019905;GO:0030276;GO:0042043;GO:0045202;GO:0048791;GO:0070382;GO:0098793","-","KOG1028-Ca2+-dependent phospholipid-binding protein Synaptotagmin, required for synaptic vesicle and secretory granule exocytosis[TU]"]
["RAB15",2.98131,8.817363,1.564400859,{"v":7.1e-16,"d":"7.10E-16"},{"v":1.87e-15,"d":"1.87E-15"},"up","RAB15","-","-","-","KOG0078-GTP-binding protein SEC4, small G protein superfamily, and related Ras family GTP-binding proteins[TU]"]
["AP1S3",8.939596,26.428829,1.563830965,{"v":2.41e-52,"d":"2.41E-52"},{"v":1.11e-51,"d":"1.11E-51"},"up","AP1S3","adaptor related protein complex 1 sigma 3 subunit","GO:0006605;GO:0006886;GO:0015031;GO:0016020;GO:0016192;GO:0030117;GO:0043231","K12395-ko04142 Lysosome","KOG0934-Clathrin adaptor complex, small subunit[U]"]
["IFT122",8.936078,26.380154,1.561739303,{"v":1.39e-195,"d":"1.39E-195"},{"v":1.5e-194,"d":"1.50E-194"},"up","IFT122","-","GO:0001843;GO:0005654;GO:0005737;GO:0005829;GO:0005929;GO:0007227;GO:0009953;GO:0010172;GO:0021914;GO:0030991;GO:0032391;GO:0035050;GO:0035115;GO:0035720;GO:0035721;GO:0036064;GO:0042733;GO:0045879;GO:0048593;GO:0050680;GO:0060173;GO:0060271;GO:0060830;GO:0060831;GO:0060971;GO:0061512;GO:0072594;GO:0097546;GO:1905515","-","KOG1538-Uncharacterized conserved protein WDR10, contains WD40 repeats[R]"]
["CDH4",2.001572,5.907789,1.561484787,{"v":1.01e-42,"d":"1.01E-42"},{"v":4.19e-42,"d":"4.19E-42"},"up","CDH4","cadherin 4","GO:0005509;GO:0005886;GO:0005887;GO:0007155;GO:0007156;GO:0007157;GO:0007411;GO:0016020;GO:0016021;GO:0045773;GO:0046872","K06797-ko04514 Cell adhesion molecules (CAMs)","KOG4289-Cadherin EGF LAG seven-pass G-type receptor[T]"]
["MMEL1",2.519782,7.430821,1.560222693,{"v":1.03e-67,"d":"1.03E-67"},{"v":5.46e-67,"d":"5.46E-67"},"up","MMEL1","-","GO:0004222;GO:0006508;GO:0008237;GO:0016020;GO:0016021","-","KOG3624-M13 family peptidase[E]"]
["CFTR",2.693187,7.934626,1.558847817,{"v":1.53e-72,"d":"1.53E-72"},{"v":8.44e-72,"d":"8.44E-72"},"up","CFTR","cystic fibrosis transmembrane conductance regulator","GO:0000166;GO:0005254;GO:0005260;GO:0005524;GO:0005737;GO:0005769;GO:0005789;GO:0005829;GO:0005886;GO:0005887;GO:0006695;GO:0006811;GO:0006821;GO:0006904;GO:0009986;GO:0015106;GO:0015108;GO:0015701;GO:0016020;GO:0016021;GO:0016324;GO:0016787;GO:0016887;GO:0019869;GO:0019899;GO:0030165;GO:0030301;GO:0031205;GO:0032991;GO:0034707;GO:0035377;GO:0035774;GO:0042626;GO:0045921;GO:0048240;GO:0050891;GO:0051087;GO:0051454;GO:0055037;GO:0055085;GO:0060081;GO:0071320;GO:1902161;GO:1902476;GO:1902943;GO:1904322","K05031-ko02010 ABC transporters;ko04024 cAMP signaling pathway;ko04152 AMPK signaling pathway;ko04971 Gastric acid secretion;ko04972 Pancreatic secretion;ko04976 Bile secretion;ko05110 Vibrio cholerae infection","KOG0054-Multidrug resistance-associated protein/mitoxantrone resistance protein, ABC superfamily[Q]"]
["MAFF",28.651911,84.258827,1.556196466,{"v":2.61e-278,"d":"2.61E-278"},{"v":3.71e-277,"d":"3.71E-277"},"up","MAFF","MAF bZIP transcription factor F","GO:0003677;GO:0003700;GO:0005634;GO:0006351;GO:0006355","-","KOG4196-bZIP transcription factor MafK[K]"]
["CNKSR2",3.520988,10.337515,1.553837207,{"v":1.58e-144,"d":"1.58E-144"},{"v":1.37e-143,"d":"1.37E-143"},"up","CNKSR2","-","GO:0005737;GO:0009966;GO:0016020","-","KOG1738-Membrane-associated guanylate kinase-interacting protein/connector enhancer of KSR-like[F]"]
["CA4",6.753107,19.781719,1.550544478,{"v":1.87e-91,"d":"1.87E-91"},{"v":1.18e-90,"d":"1.18E-90"},"up","CA4","-","GO:0004089;GO:0005791;GO:0005793;GO:0005794;GO:0005802;GO:0005886;GO:0008270;GO:0009986;GO:0015701;GO:0016020;GO:0016324;GO:0030658;GO:0030667;GO:0031225;GO:0031362;GO:0031526;GO:0046658;GO:0048471;GO:0070062","K18246-ko00910 Nitrogen metabolism;ko04964 Proximal tubule bicarbonate reclamation","KOG0382-Carbonic anhydrase[R]"]
["POPDC3",12.925989,37.857445,1.550302378,{"v":5.08e-124,"d":"5.08E-124"},{"v":3.96e-123,"d":"3.96E-123"},"up","POPDC3","popeye domain containing 3","GO:0000166;GO:0016020;GO:0016021;GO:0030552;GO:0042391","-","-"]
["KLHL21",16.061977,47.039665,1.550228307,0,0,"up","KLHL21","-","GO:0004842;GO:0005827;GO:0016567;GO:0031463;GO:0032465;GO:0035853","-","KOG4441-Proteins containing BTB/POZ and Kelch domains, involved in regulatory/signal transduction processes[TR]"]
["NR4A3",3.266804,9.564625,1.549828507,{"v":3.97e-95,"d":"3.97E-95"},{"v":2.58e-94,"d":"2.58E-94"},"up","NR4A3","-","GO:0000122;GO:0000978;GO:0001223;GO:0001707;GO:0003677;GO:0003700;GO:0003707;GO:0004879;GO:0005634;GO:0005667;GO:0006351;GO:0006355;GO:0006366;GO:0007369;GO:0007411;GO:0008270;GO:0009444;GO:0010828;GO:0019901;GO:0021766;GO:0030522;GO:0030534;GO:0032765;GO:0035035;GO:0035497;GO:0035726;GO:0038097;GO:0042472;GO:0042542;GO:0042629;GO:0043066;GO:0043303;GO:0043401;GO:0043524;GO:0043565;GO:0044320;GO:0045333;GO:0045444;GO:0045787;GO:0045893;GO:0045944;GO:0046321;GO:0046872;GO:0048008;GO:0048660;GO:0048661;GO:0048752;GO:0050679;GO:0050885;GO:0060005;GO:0071376;GO:0071870;GO:0097009;GO:1900625;GO:1903204;GO:1903208;GO:1904707;GO:1904754;GO:2000108;GO:2000253","-","KOG4217-Nuclear receptors of the nerve growth factor-induced protein B type[K]"]
["PHTF2",14.788871,43.284729,1.549346207,0,0,"up","PHTF2","putative homeodomain transcription factor 2","GO:0005783;GO:0016020;GO:0016021;GO:0003677;GO:0005634;GO:0006351;GO:0006355","-","-"]
["CUTA",29.139313,85.159149,1.547194669,{"v":1.72e-183,"d":"1.72E-183"},{"v":1.76e-182,"d":"1.76E-182"},"up","CUTA","-","GO:0005507;GO:0010038","-","-"]
["BMPER",3.925993,11.472666,1.547071176,{"v":3.74e-26,"d":"3.74E-26"},{"v":1.22e-25,"d":"1.22E-25"},"up","BMPER","BMP binding endothelial regulator","GO:0001657;GO:0002043;GO:0005576;GO:0005615;GO:0010594;GO:0030514;GO:0042118;GO:0048839;GO:0060393;GO:0070374;GO:1903672","-","KOG1216-von Willebrand factor and related coagulation proteins[WV]"]
["HS3ST3B1L",3.252876,9.494205,1.545331373,{"v":1.18e-70,"d":"1.18E-70"},{"v":6.39e-70,"d":"6.39E-70"},"up","HS3ST3B1L","-","GO:0008146;GO:0016740","K07809-ko00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin","-"]
["THBS4",1.923755,5.612203,1.544642118,{"v":2.92e-33,"d":"2.92E-33"},{"v":1.07e-32,"d":"1.07E-32"},"up","THBS4","thrombospondin 4","GO:0001938;GO:0005178;GO:0005509;GO:0005576;GO:0005604;GO:0005615;GO:0005783;GO:0007155;GO:0008201;GO:0016525;GO:0016529;GO:0031012;GO:0034103;GO:0034976;GO:0048266;GO:0050731;GO:0051451;GO:0071603;GO:0090023","K04659-ko04151 PI3K-Akt signaling pathway;ko04512 ECM-receptor interaction;ko04145 Phagosome;ko04510 Focal adhesion;ko05144 Malaria","KOG1217-Fibrillins and related proteins containing Ca2+-binding EGF-like domains[T]"]
["PRODH",43.889034,127.972885,1.543905741,0,0,"up","PRODH","-","GO:0004657;GO:0005739;GO:0006560;GO:0006562;GO:0010133;GO:0016491;GO:0055114;GO:0071949","K00318-ko00330 Arginine and proline metabolism","-"]
["AKNA",3.760675,10.956259,1.542691738,{"v":2.02e-114,"d":"2.02E-114"},{"v":1.49e-113,"d":"1.49E-113"},"up","AKNA","-","-","-","-"]
["PHKA2",3.304098,9.624016,1.542382563,{"v":6.81e-101,"d":"6.81E-101"},{"v":4.59e-100,"d":"4.59E-100"},"up","PHKA2","-","GO:0003824;GO:0004689;GO:0005516;GO:0005886;GO:0005964;GO:0005975;GO:0005977;GO:0006468;GO:0016020","K07190-ko04020 Calcium signaling pathway;ko04910 Insulin signaling pathway;ko04922 Glucagon signaling pathway","KOG3635-Phosphorylase kinase[G]"]
["BPGM",13.984927,40.729053,1.542185547,0,0,"up","BPGM","bisphosphoglycerate mutase","GO:0003824;GO:0004082;GO:0004619;GO:0005829;GO:0006094;GO:0006096;GO:0008152;GO:0016853;GO:0016868;GO:0043456;GO:0046538","K01837-ko00010 Glycolysis / Gluconeogenesis;ko00260 Glycine, serine and threonine metabolism","KOG0235-Phosphoglycerate mutase[G]"]
["PLEKHH2",8.301313,24.165836,1.541557457,{"v":5.06e-255,"d":"5.06E-255"},{"v":6.75e-254,"d":"6.75E-254"},"up","PLEKHH2","-","GO:0003779;GO:0005654;GO:0005737;GO:0005829;GO:0005856;GO:0005886;GO:0016604;GO:0030027;GO:0030835;GO:0030864;GO:0042802","-","KOG0248-Cytoplasmic protein Max-1, contains PH, MyTH4 and FERM domains[Z]"]
["CHST7",1.956682,5.696002,1.541540345,{"v":9.21e-20,"d":"9.21E-20"},{"v":2.66e-19,"d":"2.66E-19"},"up","CHST7","-","GO:0001517;GO:0006044;GO:0006790;GO:0008146;GO:0008459;GO:0016740;GO:0030206","K04743-ko00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate","-"]
["MPZL1",6.308103,18.355011,1.540895857,{"v":2.74e-178,"d":"2.74E-178"},{"v":2.75e-177,"d":"2.75E-177"},"up","MPZL1","-","-","K06770-ko04514 Cell adhesion molecules (CAMs)","-"]
["CACNB1",7.426963,21.606901,1.54064787,{"v":1.17e-154,"d":"1.17E-154"},{"v":1.06e-153,"d":"1.06E-153"},"up","CACNB1","-","-","K04862-ko04010 MAPK signaling pathway;ko04921 Oxytocin signaling pathway;ko04260 Cardiac muscle contraction;ko04261 Adrenergic signaling in cardiomyocytes;ko05410 Hypertrophic cardiomyopathy (HCM);ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC);ko05414 Dilated cardiomyopathy (DCM)","KOG3812-L-type voltage-dependent Ca2+ channel, beta subunit[PT]"]
["TUBA4A",19.784191,57.556484,1.540630391,{"v":4.44e-216,"d":"4.44E-216"},{"v":5.21e-215,"d":"5.21E-215"},"up","TUBA4A","-","GO:0000166;GO:0003924;GO:0005200;GO:0005525;GO:0005737;GO:0005856;GO:0005874;GO:0007010;GO:0007017","K07374-ko04145 Phagosome;ko04210 Apoptosis;ko04540 Gap junction;ko05130 Pathogenic Escherichia coli infection","-"]
["GLIS1",2.251897,6.548726,1.540073428,{"v":4.14e-40,"d":"4.14E-40"},{"v":1.67e-39,"d":"1.67E-39"},"up","GLIS1","-","GO:0000122;GO:0000977;GO:0001227;GO:0001228;GO:0003676;GO:0003677;GO:0005634;GO:0006357;GO:0006366;GO:0045893;GO:0045944","-","KOG2462-C2H2-type Zn-finger protein[K]"]
["CDK2AP1",30.035599,87.294266,1.539213456,{"v":9.7e-200,"d":"9.70E-200"},{"v":1.06e-198,"d":"1.06E-198"},"up","CDK2AP1","cyclin-dependent kinase 2 associated protein 1","-","-","KOG4713-Cyclin-dependent kinase 2-associated protein[TD]"]
["USP28",4.689246,13.606135,1.536829438,{"v":2.73e-111,"d":"2.73E-111"},{"v":1.97e-110,"d":"1.97E-110"},"up","USP28","ubiquitin specific peptidase 28","GO:0000077;GO:0004843;GO:0005654;GO:0006511;GO:0006974;GO:0007265;GO:0008283;GO:0010212;GO:0016579;GO:0016604;GO:0031647;GO:0032991;GO:0034644;GO:0036459;GO:0042771;GO:0000077;GO:0004843;GO:0005634;GO:0005654;GO:0006281;GO:0006508;GO:0006511;GO:0006974;GO:0007265;GO:0008233;GO:0008234;GO:0008283;GO:0010212;GO:0016579;GO:0016787;GO:0031647;GO:0036459;GO:0042771","-","KOG1863-Ubiquitin carboxyl-terminal hydrolase[O]"]
["SIX4",8.851558,25.680239,1.536655312,0,0,"up","SIX4","-","GO:0000978;GO:0003677;GO:0003700;GO:0005634;GO:0005737;GO:0006355;GO:0006366;GO:0007519;GO:0008582;GO:0008584;GO:0010468;GO:0030238;GO:0030910;GO:0032880;GO:0034504;GO:0042472;GO:0043066;GO:0043524;GO:0043565;GO:0043586;GO:0045214;GO:0045892;GO:0045893;GO:0045944;GO:0046661;GO:0048538;GO:0048699;GO:0048701;GO:0048704;GO:0048856;GO:0050678;GO:0051451;GO:0060037;GO:0061055;GO:0061197;GO:0061551;GO:0072075;GO:0072095;GO:0072107;GO:0090190;GO:0098528;GO:1902725","-","KOG0775-Transcription factor SIX and related HOX domain proteins[K]"]
["COMP",113.256546,327.79953,1.533219348,0,0,"up","COMP","-","GO:0002020;GO:0003417;GO:0005509;GO:0005518;GO:0005576;GO:0007155;GO:0008201;GO:0043066;GO:0043395;GO:0060173","K04659-ko04151 PI3K-Akt signaling pathway;ko04512 ECM-receptor interaction;ko04145 Phagosome;ko04510 Focal adhesion;ko05144 Malaria","-"]
["ATRN",45.987953,132.914902,1.531174977,0,0,"up","ATRN","-","GO:0005615;GO:0016020;GO:0016021;GO:0021549;GO:0038023;GO:0040014;GO:0042552;GO:0043473","-","KOG1388-Attractin and platelet-activating factor acetylhydrolase[TV]"]
["PLEKHM2",13.302593,38.441315,1.530950199,0,0,"up","PLEKHM2","-","GO:0007030;GO:0010008;GO:0019894;GO:0032418;GO:0032880;GO:1903527","K15348-ko05132 Salmonella infection","KOG4381-RUN domain-containing protein[T]"]
["ABCA9",6.432676,18.567619,1.529297894,{"v":1.44e-175,"d":"1.44E-175"},{"v":1.44e-174,"d":"1.44E-174"},"up","ABCA9","-","GO:0000166;GO:0005524;GO:0016020;GO:0016021;GO:0016887;GO:0042626;GO:0055085","K05651-ko02010 ABC transporters","-"]
["KCTD5",5.656672,16.311375,1.527852978,{"v":1.17e-297,"d":"1.17E-297"},{"v":1.77e-296,"d":"1.77E-296"},"up","KCTD5","-","GO:0005829;GO:0031463;GO:0042802;GO:0043161;GO:0044877;GO:0051260;GO:0097602","-","-"]
["LOC101748700",6.636,19.124464,1.527033523,{"v":3.95e-14,"d":"3.95E-14"},{"v":9.92e-14,"d":"9.92E-14"},"up","LOC101748700","-","-","-","-"]
["ADSSL1",33.276363,95.871025,1.526597097,0,0,"up","ADSSL1","-","GO:0000166;GO:0000287;GO:0004019;GO:0005525;GO:0005737;GO:0006163;GO:0006164;GO:0006167;GO:0016874;GO:0044208;GO:0046040;GO:0046872","K01939-ko00230 Purine metabolism;ko00250 Alanine, aspartate and glutamate metabolism","KOG1355-Adenylosuccinate synthase[F]"]
["TCP11L1",4.832266,13.86981,1.521176247,{"v":1.83e-114,"d":"1.83E-114"},{"v":1.35e-113,"d":"1.35E-113"},"up","TCP11L1","t-complex 11 like 1","GO:0005874","-","KOG1981-SOK1 kinase belonging to the STE20/SPS1/GC kinase family[T]"]
["LOC107055491",34.507145,99.029434,1.520962278,{"v":6.23e-282,"d":"6.23E-282"},{"v":8.95e-281,"d":"8.95E-281"},"up","LOC107055491","-","-","-","-"]
["RNF144A",4.363416,12.468778,1.514790152,{"v":2.9e-121,"d":"2.90E-121"},{"v":2.22e-120,"d":"2.22E-120"},"up","RNF144A","-","GO:0000151;GO:0000209;GO:0004842;GO:0005794;GO:0016020;GO:0016021;GO:0016567;GO:0016740;GO:0031624;GO:0032436;GO:0046872;GO:0061630","-","KOG1814-Predicted E3 ubiquitin ligase[O]"]
["MSC",21.517523,61.45665,1.514057117,{"v":3.6e-177,"d":"3.60E-177"},{"v":3.61e-176,"d":"3.61E-176"},"up","MSC","-","GO:0000122;GO:0000980;GO:0005634;GO:0005654;GO:0014707;GO:0046983;GO:0060021;GO:1990830","-","KOG4447-Transcription factor TWIST[K]"]
["VCAM1",4.291427,12.24623,1.512808322,{"v":4.85e-183,"d":"4.85E-183"},{"v":4.97e-182,"d":"4.97E-182"},"up","VCAM1","-","GO:0002102;GO:0005178;GO:0005615;GO:0005769;GO:0005783;GO:0005794;GO:0005902;GO:0007155;GO:0007157;GO:0007159;GO:0007160;GO:0008131;GO:0009308;GO:0009897;GO:0009986;GO:0016020;GO:0016021;GO:0022614;GO:0030175;GO:0035584;GO:0042102;GO:0045177;GO:0050839;GO:0050901;GO:0055114;GO:0071065;GO:0098609","K06527-ko04064 NF-kappa B signaling pathway;ko04668 TNF signaling pathway;ko04514 Cell adhesion molecules (CAMs);ko04670 Leukocyte transendothelial migration;ko04933 AGE-RAGE signaling pathway in diabetic complications;ko05166 HTLV-I infection;ko05144 Malaria;ko05143 African trypanosomiasis","-"]
["TPD52L1",2.872469,8.186103,1.510885496,{"v":2.46e-35,"d":"2.46E-35"},{"v":9.27e-35,"d":"9.27E-35"},"up","TPD52L1","tumor protein D52-like 1","GO:0000086;GO:0005737;GO:0005769;GO:0042803;GO:0048471","-","KOG4010-Coiled-coil protein TPD52[R]"]
["CSGALNACT1",8.758589,24.941288,1.509765593,{"v":3.21e-139,"d":"3.21E-139"},{"v":2.7e-138,"d":"2.70E-138"},"up","CSGALNACT1","-","GO:0001958;GO:0005794;GO:0008376;GO:0008955;GO:0015020;GO:0016020;GO:0016021;GO:0016740;GO:0019276;GO:0030198;GO:0030204;GO:0030206;GO:0032580;GO:0046398;GO:0047237;GO:0047238;GO:0050653;GO:0051216","K00746-ko00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate","KOG3588-Chondroitin synthase 1[G]"]
["EVA1CL",4.405592,12.545405,1.509751247,{"v":5.25e-34,"d":"5.25E-34"},{"v":1.95e-33,"d":"1.95E-33"},"up","EVA1CL","-","GO:0030246","-","-"]
["KCNIP4",2.640136,7.517168,1.509576998,{"v":4.51e-32,"d":"4.51E-32"},{"v":1.63e-31,"d":"1.63E-31"},"up","KCNIP4","potassium voltage-gated channel interacting protein 4","GO:0005509;GO:0005737;GO:0005886;GO:0008076;GO:0015459;GO:0016020;GO:0016021;GO:1901379","-","KOG0044-Ca2+ sensor (EF-Hand superfamily)[T]"]
["COL8A2",8.397742,23.889269,1.508289338,{"v":1.68e-261,"d":"1.68E-261"},{"v":2.28e-260,"d":"2.28E-260"},"up","COL8A2","-","GO:0005576;GO:0005581;GO:0048593;GO:0050673","-","-"]
["ZSWIM5",6.763887,19.234125,1.507743737,{"v":8.8e-192,"d":"8.80E-192"},{"v":9.34e-191,"d":"9.34E-191"},"up","ZSWIM5","-","GO:0008270","-","KOG3615-Uncharacterized conserved protein[S]"]
["LOC107049115",3.576432,10.155728,1.505700745,{"v":1.82e-23,"d":"1.82E-23"},{"v":5.64e-23,"d":"5.64E-23"},"up","LOC107049115","-","GO:0016020;GO:0016021","-","-"]
["LOC107054982",36.677444,104.095016,1.504935987,0,0,"up","LOC107054982","-","-","-","-"]
["ITGAD",7.138336,20.225235,1.50249675,{"v":8.3e-109,"d":"8.30E-109"},{"v":5.89e-108,"d":"5.89E-108"},"up","ITGAD","-","GO:0007155;GO:0007229;GO:0008305;GO:0016020;GO:0016021","-","-"]
["SHISA2",8.307625,23.536409,1.502386222,{"v":5.71e-113,"d":"5.71E-113"},{"v":4.17e-112,"d":"4.17E-112"},"up","SHISA2","shisa family member 2","GO:0005783;GO:0016020;GO:0016021;GO:0030178;GO:0040037","-","-"]
["HIST1H46L6",6.26424,17.721575,1.500295436,{"v":1.18e-13,"d":"1.18E-13"},{"v":2.93e-13,"d":"2.93E-13"},"up","HIST1H46L6","-","-","-","-"]
["OIT3",2.974967,8.41036,1.49929389,{"v":2.41e-38,"d":"2.41E-38"},{"v":9.47e-38,"d":"9.47E-38"},"up","OIT3","-","GO:0005509;GO:1903118","-","KOG1214-Nidogen and related basement membrane protein proteins[MW]"]
["PPIF",10.663481,30.04563,1.494476703,{"v":1.94e-111,"d":"1.94E-111"},{"v":1.4e-110,"d":"1.40E-110"},"up","PPIF","peptidylprolyl isomerase F","GO:0000413;GO:0003755;GO:0006457;GO:0016853;GO:0000413;GO:0002931;GO:0003755;GO:0005739;GO:0005757;GO:0006457;GO:0006979;GO:0008637;GO:0010849;GO:0010939;GO:0016018;GO:0016853;GO:0032780;GO:0043066;GO:0046902;GO:0070266;GO:0070301;GO:0071243;GO:0071277;GO:0090200;GO:0090201;GO:0090324;GO:1902445;GO:1902686;GO:2000276;GO:2001243","K09565-ko04020 Calcium signaling pathway;ko04022 cGMP - PKG signaling pathway;ko05012 Parkinson's disease;ko05016 Huntington's disease;ko05145 Toxoplasmosis","KOG0865-Cyclophilin type peptidyl-prolyl cis-trans isomerase[O]"]
["AIFM2",10.54993,29.721895,1.494292675,{"v":4.42e-80,"d":"4.42E-80"},{"v":2.58e-79,"d":"2.58E-79"},"up","AIFM2","-","GO:0003677;GO:0004174;GO:0005737;GO:0005739;GO:0005741;GO:0005811;GO:0005829;GO:0008637;GO:0016491;GO:0022904;GO:0043065;GO:0050660;GO:0055114","-","KOG1336-Monodehydroascorbate/ferredoxin reductase[R]"]
["TTC30B",7.927934,22.32749,1.493804219,{"v":2.16e-98,"d":"2.16E-98"},{"v":1.43e-97,"d":"1.43E-97"},"up","TTC30B","tetratricopeptide repeat domain 30B","GO:0005929;GO:0030992;GO:0042073;GO:0060271","-","-"]
["ABCC9",4.576821,12.885472,1.49332761,{"v":8.71e-130,"d":"8.71E-130"},{"v":6.98e-129,"d":"6.98E-129"},"up","ABCC9","-","GO:0000166;GO:0005267;GO:0005524;GO:0005886;GO:0006813;GO:0008076;GO:0008281;GO:0008282;GO:0016020;GO:0016021;GO:0016887;GO:0030017;GO:0042383;GO:0042493;GO:0042626;GO:0044325;GO:0051607;GO:0055085;GO:0071805","K05033-ko02010 ABC transporters","KOG0054-Multidrug resistance-associated protein/mitoxantrone resistance protein, ABC superfamily[Q]"]
["CERS4",12.665281,35.643032,1.49274098,{"v":8.58e-188,"d":"8.58E-188"},{"v":8.95e-187,"d":"8.95E-187"},"up","CERS4","-","GO:0003677;GO:0005634;GO:0016020;GO:0016021","K04710-ko00600 Sphingolipid metabolism;ko04071 Sphingolipid signaling pathway","-"]
["HACD1",8.155066,22.943501,1.492317094,{"v":1.47e-247,"d":"1.47E-247"},{"v":1.91e-246,"d":"1.91E-246"},"up","HACD1","-","GO:0005783;GO:0005789;GO:0006629;GO:0006631;GO:0006633;GO:0016020;GO:0016021;GO:0016829;GO:0018812;GO:0030148;GO:0030176;GO:0030497;GO:0042761;GO:0102158;GO:0102343;GO:0102344;GO:0102345","K10703-ko01212 Fatty acid metabolism;ko00062 Fatty acid elongation;ko01040 Biosynthesis of unsaturated fatty acids","KOG3187-Protein tyrosine phosphatase-like protein PTPLA (contains Pro instead of catalytic Arg)[R]"]
["GSC",2.099285,5.903872,1.491763402,{"v":7.99e-11,"d":"7.99E-11"},{"v":1.81e-10,"d":"1.81E-10"},"up","GSC","goosecoid homeobox","GO:0000122;GO:0000978;GO:0001085;GO:0001103;GO:0003677;GO:0005634;GO:0005667;GO:0006355;GO:0007275;GO:0009653;GO:0014036;GO:0016604;GO:0021904;GO:0023019;GO:0030178;GO:0030900;GO:0042474;GO:0043565;GO:0043583;GO:0048644;GO:0048704","-","KOG0484-Transcription factor PHOX2/ARIX, contains HOX domain[K]"]
["MOSPD1",49.59111,139.401154,1.491089082,0,0,"up","MOSPD1","-","GO:0000122;GO:0005634;GO:0005737;GO:0016020;GO:0016021;GO:0045944;GO:0048471","-","-"]
["TPM2",2128.007812,5962.030273,1.486300254,0,0,"up","TPM2","tropomyosin 2 (beta)","GO:0003779;GO:0005515;GO:0005737;GO:0005856;GO:0005862;GO:0005884;GO:0006936;GO:0007015;GO:0008307;GO:0015629;GO:0042802;GO:0042803;GO:0046982;GO:0051015","K09290-ko04260 Cardiac muscle contraction;ko04261 Adrenergic signaling in cardiomyocytes;ko05200 Pathways in cancer;ko05216 Thyroid cancer;ko05410 Hypertrophic cardiomyopathy (HCM);ko05414 Dilated cardiomyopathy (DCM)","-"]
["EFCAB2",5.866769,16.385511,1.481782572,{"v":3.58e-19,"d":"3.58E-19"},{"v":1.02e-18,"d":"1.02E-18"},"up","EFCAB2","-","GO:0005509","-","KOG0027-Calmodulin and related proteins (EF-Hand superfamily)[T]"]
["HADHA",96.436607,268.951691,1.479694262,0,0,"up","HADHA","hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit","GO:0003824;GO:0003857;GO:0004300;GO:0005739;GO:0006631;GO:0006635;GO:0008152;GO:0016491;GO:0016507;GO:0016509;GO:0032868;GO:0042645;GO:0055114","K07515-ko01200 Carbon metabolism;ko01212 Fatty acid metabolism;ko00640 Propanoate metabolism;ko00650 Butanoate metabolism;ko00062 Fatty acid elongation;ko00071 Fatty acid degradation;ko01040 Biosynthesis of unsaturated fatty acids;ko00280 Valine, leucine and isoleucine degradation;ko00310 Lysine degradation;ko00380 Tryptophan metabolism;ko00410 beta-Alanine metabolism;ko00627 Aminobenzoate degradation;ko00930 Caprolactam degradation","KOG1683-Hydroxyacyl-CoA dehydrogenase/enoyl-CoA hydratase[I]"]
["NXPE3",2.786301,7.756087,1.476977868,{"v":9.58e-68,"d":"9.58E-68"},{"v":5.08e-67,"d":"5.08E-67"},"up","NXPE3","-","-","-","-"]
["TMEM67",4.520716,12.581311,1.476659069,{"v":6.26e-119,"d":"6.26E-119"},{"v":4.72e-118,"d":"4.72E-118"},"up","TMEM67","-","GO:0010826;GO:0016020;GO:0016021;GO:0036038;GO:0060271","-","KOG4611-Uncharacterized conserved protein[S]"]
["PISD",9.098394,25.311712,1.476121274,{"v":1.2e-163,"d":"1.20E-163"},{"v":1.14e-162,"d":"1.14E-162"},"up","PISD","-","GO:0004609;GO:0005634;GO:0005739;GO:0005743;GO:0006629;GO:0006646;GO:0008654;GO:0016020;GO:0016021;GO:0016540;GO:0016829;GO:0016831;GO:0031305","K01613-ko00564 Glycerophospholipid metabolism","KOG2420-Phosphatidylserine decarboxylase[I]"]
["LOC112530287",3.55859,9.894688,1.475348493,{"v":3.88e-42,"d":"3.88E-42"},{"v":1.6e-41,"d":"1.60E-41"},"up","LOC112530287","-","-","-","-"]
["SLC41A3",10.938651,30.370729,1.473246709,{"v":4.48e-119,"d":"4.48E-119"},{"v":3.38e-118,"d":"3.38E-118"},"up","SLC41A3","-","GO:0006812;GO:0008324;GO:0016020;GO:0016021;GO:0098655","-","KOG3788-Predicted divalent cation transporter[P]"]
["MAP7D1",27.491425,76.308701,1.472865878,0,0,"up","MAP7D1","-","GO:0000226;GO:0005198;GO:0005829;GO:0015630","-","-"]
["NUDT4",31.750351,88.114853,1.472612685,0,0,"up","NUDT4","-","GO:0000298;GO:0005634;GO:0005737;GO:0008486;GO:0016787;GO:0034431;GO:0034432;GO:0050072;GO:0071543;GO:1901907;GO:1901909;GO:1901911","-","-"]
["NEDD9",6.535271,18.131586,1.472186159,{"v":6.95e-143,"d":"6.95E-143"},{"v":5.96e-142,"d":"5.96E-142"},"up","NEDD9","-","GO:0000922;GO:0005634;GO:0005654;GO:0005829;GO:0005886;GO:0006929;GO:0030335;GO:0036032;GO:0048041;GO:0061098;GO:0090527;GO:1900026;GO:1990782","-","KOG0162-Myosin class I heavy chain[Z]"]
["LOC419851",12.302606,34.10733,1.471117875,{"v":1.08e-159,"d":"1.08E-159"},{"v":1.01e-158,"d":"1.01E-158"},"up","LOC419851","complement component 4 binding protein, alpha chain","-","-","-"]
["PDHX",14.112761,39.038296,1.467889819,{"v":5.08e-192,"d":"5.08E-192"},{"v":5.39e-191,"d":"5.39E-191"},"up","PDHX","pyruvate dehydrogenase complex component X","GO:0006086;GO:0008152;GO:0016740;GO:0016746;GO:0034604;GO:0045254","K13997-ko00010 Glycolysis / Gluconeogenesis;ko00020 Citrate cycle (TCA cycle);ko00620 Pyruvate metabolism","KOG0557-Dihydrolipoamide acetyltransferase[C]"]
["SPEG",10.308911,28.512024,1.467678517,0,0,"up","SPEG","-","GO:0004672;GO:0004674;GO:0005524;GO:0006468;GO:0016301;GO:0016310","-","-"]
["ANAPC15",30.274626,83.7202,1.46746662,{"v":9.78e-97,"d":"9.78E-97"},{"v":6.43e-96,"d":"6.43E-96"},"up","ANAPC15","-","GO:0005680;GO:0090266","-","-"]
["GRAMD1B",6.495937,17.954714,1.466753127,{"v":2.02e-268,"d":"2.02E-268"},{"v":2.8e-267,"d":"2.80E-267"},"up","GRAMD1B","-","GO:0016020;GO:0016021","-","KOG1032-Uncharacterized conserved protein, contains GRAM domain[S]"]
["AKR1B10L1",125.009979,344.923309,1.464232362,0,0,"up","AKR1B10L1","aldo-keto reductase family 1 member B10-like 1","GO:0016491;GO:0055114","K00011-ko00040 Pentose and glucuronate interconversions;ko00051 Fructose and mannose metabolism;ko00052 Galactose metabolism;ko00561 Glycerolipid metabolism","KOG1577-Aldo/keto reductase family proteins[R]"]
["GLRX",4.52825,12.488126,1.463531484,{"v":2.1e-13,"d":"2.10E-13"},{"v":5.16e-13,"d":"5.16E-13"},"up","GLRX","glutaredoxin","GO:0005634;GO:0005737;GO:0009055;GO:0015035;GO:0022900;GO:0045454;GO:0045838;GO:0047485;GO:0055114;GO:2000651;GO:0005737;GO:0009055;GO:0015035;GO:0022900;GO:0045454;GO:0055114","-","KOG1752-Glutaredoxin and related proteins[O]"]
["PLIN1",10.467551,28.836266,1.461960415,{"v":4.95e-105,"d":"4.95E-105"},{"v":3.41e-104,"d":"3.41E-104"},"up","PLIN1","perilipin 1","GO:0005811;GO:0005829;GO:0016042","K08768-ko04923 Regulation of lipolysis in adipocyte;ko03320 PPAR signaling pathway","-"]
["ARF5",2.885218,7.94787,1.461887946,{"v":2.74e-08,"d":"2.74E-08"},{"v":5.57e-08,"d":"5.57E-08"},"up","ARF5","ADP-ribosylation factor 5","GO:0000166;GO:0005525;GO:0005622;GO:0005737;GO:0005794;GO:0005886;GO:0015031;GO:0016192","K07940-ko04144 Endocytosis","-"]
["CNTRL",7.219643,19.885151,1.461692112,{"v":6.18e-254,"d":"6.18E-254"},{"v":8.21e-253,"d":"8.21E-253"},"up","CNTRL","centriolin","GO:0000278;GO:0005813;GO:0005829;GO:0051301;GO:0120103","-","KOG1644-U2-associated snRNP A' protein[A]"]
["ZKSCAN7L",2.330442,6.411885,1.460144943,{"v":3.42e-17,"d":"3.42E-17"},{"v":9.33e-17,"d":"9.33E-17"},"up","ZKSCAN7L","-","GO:0003676","-","-"]
["PITPNM3",3.046343,8.372422,1.458566641,{"v":2.66e-129,"d":"2.66E-129"},{"v":2.13e-128,"d":"2.13E-128"},"up","PITPNM3","-","GO:0005509;GO:0016020;GO:0016021;GO:0030971;GO:0046872","-","KOG2308-Phosphatidic acid-preferring phospholipase A1, contains DDHD domain[IU]"]
["RFTN2",6.364057,17.47821,1.457538779,{"v":2.04e-182,"d":"2.04E-182"},{"v":2.09e-181,"d":"2.09E-181"},"up","RFTN2","raftlin family member 2","GO:0033227;GO:0043330","-","-"]
["NUAK1",19.83164,54.38829,1.45549208,0,0,"up","NUAK1","-","GO:0001650;GO:0002039;GO:0004672;GO:0004674;GO:0005524;GO:0005634;GO:0005737;GO:0006468;GO:0015630;GO:0030155;GO:0035507;GO:0035556;GO:2000772","-","KOG0611-Predicted serine/threonine protein kinase[R]"]
["ACAD9",102.961037,281.888733,1.453027326,0,0,"up","ACAD9","acyl-CoA dehydrogenase family member 9","GO:0001676;GO:0003995;GO:0004466;GO:0005634;GO:0005739;GO:0016491;GO:0016627;GO:0030425;GO:0031966;GO:0032981;GO:0050660;GO:0051791;GO:0055114;GO:0070991","-","KOG0137-Very-long-chain acyl-CoA dehydrogenase[I]"]
["HOXA5",9.103023,24.914848,1.452588142,{"v":2.59e-57,"d":"2.59E-57"},{"v":1.26e-56,"d":"1.26E-56"},"up","HOXA5","homeobox A5","GO:0000978;GO:0001501;GO:0002009;GO:0003016;GO:0003677;GO:0003700;GO:0005634;GO:0006351;GO:0006355;GO:0006366;GO:0007275;GO:0007389;GO:0007585;GO:0009952;GO:0010870;GO:0016477;GO:0016525;GO:0030324;GO:0030878;GO:0033599;GO:0035264;GO:0043065;GO:0043565;GO:0045639;GO:0045647;GO:0045944;GO:0048286;GO:0048704;GO:0048706;GO:0060435;GO:0060439;GO:0060441;GO:0060480;GO:0060481;GO:0060484;GO:0060535;GO:0060536;GO:0060574;GO:0060638","-","KOG0489-Transcription factor zerknullt and related HOX domain proteins[R]"]
["RGN",9.412898,25.726908,1.45056721,{"v":4.38e-52,"d":"4.38E-52"},{"v":2.01e-51,"d":"2.01E-51"},"up","RGN","regucalcin","GO:0004341;GO:0005509;GO:0005576;GO:0005634;GO:0005737;GO:0006874;GO:0008270;GO:0016787;GO:0019853;GO:0030234;GO:0032781;GO:0046872;GO:0050790;GO:0050848","K01053-ko01200 Carbon metabolism;ko01220 Degradation of aromatic compounds;ko00030 Pentose phosphate pathway;ko00053 Ascorbate and aldarate metabolism;ko00930 Caprolactam degradation","KOG4499-Ca2+-binding protein Regucalcin/SMP30[PT]"]
["FAM167B",2.978239,8.136804,1.450002706,{"v":4.07e-21,"d":"4.07E-21"},{"v":1.21e-20,"d":"1.21E-20"},"up","FAM167B","-","-","-","-"]
["GSTA2",34.922577,95.350021,1.449073234,{"v":1.49e-303,"d":"1.49E-303"},{"v":2.29e-302,"d":"2.29E-302"},"up","GSTA2","glutathione S-transferase alpha 2","GO:0004364;GO:0008152","K00799-ko00480 Glutathione metabolism;ko00980 Metabolism of xenobiotics by cytochrome P450;ko00982 Drug metabolism - cytochrome P450;ko05204 Chemical carcinogenesis;ko01524 Platinum drug resistance","KOG1695-Glutathione S-transferase[O]"]
["CDAN1",3.847026,10.492544,1.447549028,{"v":9.89e-125,"d":"9.89E-125"},{"v":7.73e-124,"d":"7.73E-124"},"up","CDAN1","-","GO:0005634;GO:0005737;GO:0005829;GO:0005886;GO:0006325;GO:0008104;GO:0008156;GO:0012505;GO:0031497","-","-"]
["LOC107055082",10.732121,29.261372,1.44706219,{"v":2.57e-41,"d":"2.57E-41"},{"v":1.06e-40,"d":"1.06E-40"},"up","LOC107055082","-","-","-","-"]
["ACO2",125.345924,340.817352,1.443083706,0,0,"up","ACO2","aconitase 2","GO:0003994;GO:0005506;GO:0005739;GO:0005759;GO:0006099;GO:0006101;GO:0008152;GO:0016829;GO:0043209;GO:0046872;GO:0051536;GO:0051539;GO:0003994;GO:0005739;GO:0006099;GO:0008152;GO:0016829;GO:0046872;GO:0051536;GO:0051539","K01681-ko01200 Carbon metabolism;ko01210 2-Oxocarboxylic acid metabolism;ko01230 Biosynthesis of amino acids;ko00020 Citrate cycle (TCA cycle);ko00630 Glyoxylate and dicarboxylate metabolism;ko00720 Carbon fixation pathways in prokaryotes","KOG0453-Aconitase/homoaconitase (aconitase superfamily)[CE]"]
["CAPN6",6.391001,17.366421,1.442186645,{"v":1.34e-247,"d":"1.34E-247"},{"v":1.74e-246,"d":"1.74E-246"},"up","CAPN6","-","GO:0001578;GO:0004198;GO:0005622;GO:0005737;GO:0005829;GO:0005874;GO:0005876;GO:0006508;GO:0008017;GO:0008233;GO:0008234;GO:0016787;GO:0048471;GO:0051493","-","KOG0045-Cytosolic Ca2+-dependent cysteine protease (calpain), large subunit (EF-Hand protein superfamily)[OT]"]
["MBNL2",23.236897,63.019867,1.439389282,0,0,"up","MBNL2","muscleblind like splicing regulator 2","GO:0000381;GO:0005654;GO:0043484;GO:0046872","-","KOG2494-C3H1-type Zn-finger protein[K]"]
["SMIM11",23.196312,62.892506,1.438992674,{"v":2.45e-87,"d":"2.45E-87"},{"v":1.51e-86,"d":"1.51E-86"},"up","SMIM11","-","-","-","-"]
["LOC112530461",2.025781,5.485501,1.437145172,{"v":2.05e-12,"d":"2.05E-12"},{"v":4.9e-12,"d":"4.90E-12"},"up","LOC112530461","-","-","-","-"]
["FXR1",61.810947,167.190231,1.435556279,0,0,"up","FXR1","FMR1 autosomal homolog 1","GO:0003676;GO:0003723;GO:0002151;GO:0003676;GO:0003723;GO:0003730;GO:0005634;GO:0005737;GO:0005829;GO:0005844;GO:0007517;GO:0017148;GO:0030424;GO:0030425;GO:0033592;GO:0035770;GO:0042803;GO:0043034;GO:0043197;GO:0046982;GO:0048471;GO:0098794;GO:0098978;GO:2000637","K15516-ko03013 RNA transport","-"]
["PDE7B",14.066005,38.024509,1.434716984,0,0,"up","PDE7B","-","GO:0004114;GO:0007165;GO:0008081;GO:0016787;GO:0046872","K18436-ko00230 Purine metabolism;ko05032 Morphine addiction","KOG3689-Cyclic nucleotide phosphodiesterase[T]"]
["LOC112532547",7.708311,20.819323,1.433436471,{"v":7.25e-42,"d":"7.25E-42"},{"v":2.99e-41,"d":"2.99E-41"},"up","LOC112532547","-","-","-","-"]
["CISH",27.862803,75.247681,1.433306721,{"v":3.79e-156,"d":"3.79E-156"},{"v":3.46e-155,"d":"3.46E-155"},"up","CISH","cytokine inducible SH2 containing protein","GO:0004860;GO:0005737;GO:0006469;GO:0009968;GO:0016567;GO:0019221;GO:0035556;GO:0040008;GO:0046426;GO:0046627;GO:0005622;GO:0005886;GO:0007205;GO:0016567;GO:0035556","-","KOG4566-Cytokine-inducible SH2 protein[T]"]
["DUSP22AL",3.30946,8.92475,1.431215923,{"v":4.21e-21,"d":"4.21E-21"},{"v":1.25e-20,"d":"1.25E-20"},"up","DUSP22AL","-","GO:0004725;GO:0006470;GO:0007179;GO:0008138;GO:0016311;GO:0016787;GO:0016791;GO:0035335;GO:0042127;GO:0046330","-","-"]
["CPZ",10.372373,27.962236,1.430733738,{"v":3.14e-123,"d":"3.14E-123"},{"v":2.42e-122,"d":"2.42E-122"},"up","CPZ","carboxypeptidase Z","GO:0004180;GO:0004181;GO:0004185;GO:0005576;GO:0005615;GO:0006508;GO:0006518;GO:0007275;GO:0008233;GO:0008237;GO:0008270;GO:0016055;GO:0016485;GO:0016787;GO:0046872","-","KOG2649-Zinc carboxypeptidase[R]"]
["PNPO",4.791709,12.9154,1.430480124,{"v":2.4e-29,"d":"2.40E-29"},{"v":8.3e-29,"d":"8.30E-29"},"up","PNPO","-","GO:0004733;GO:0005654;GO:0005829;GO:0008615;GO:0010181;GO:0016638;GO:0030170;GO:0042803;GO:0042823;GO:0048037;GO:0055114","K00275-ko00750 Vitamin B6 metabolism","KOG2586-Pyridoxamine-phosphate oxidase[H]"]
["TPI1",281.406219,757.917419,1.429386452,0,0,"up","TPI1","triosephosphate isomerase 1","GO:0003824;GO:0004807;GO:0005829;GO:0006094;GO:0006096;GO:0008152;GO:0016853;GO:0019563;GO:0046166","K01803-ko01200 Carbon metabolism;ko01230 Biosynthesis of amino acids;ko00010 Glycolysis / Gluconeogenesis;ko00051 Fructose and mannose metabolism;ko00562 Inositol phosphate metabolism;ko00710 Carbon fixation in photosynthetic organisms","KOG1643-Triosephosphate isomerase[G]"]
["IL18",2.801315,7.536358,1.427763279,{"v":6.57e-52,"d":"6.57E-52"},{"v":3.01e-51,"d":"3.01E-51"},"up","IL18","interleukin 18","GO:0005125;GO:0005576;GO:0005615;GO:0006954;GO:0006955;GO:0010469;GO:0035710;GO:0050671;GO:1902715","K05482-ko04060 Cytokine-cytokine receptor interaction;ko04621 NOD-like receptor signaling pathway;ko04623 Cytosolic DNA-sensing pathway;ko05323 Rheumatoid arthritis;ko05321 Inflammatiory bowel disease (IBD);ko05132 Salmonella infection;ko05134 Legionellosis;ko05152 Tuberculosis;ko05164 Influenza A;ko05144 Malaria;ko05143 African trypanosomiasis","-"]
["CRHR2",6.6202,17.809458,1.427696904,{"v":2.79e-58,"d":"2.79E-58"},{"v":1.37e-57,"d":"1.37E-57"},"up","CRHR2","corticotropin releasing hormone receptor 2","GO:0004888;GO:0004930;GO:0007165;GO:0007166;GO:0007186;GO:0009755;GO:0016020;GO:0016021;GO:0032099;GO:0043404;GO:0043435","K04579-ko04080 Neuroactive ligand-receptor interaction","-"]
["LOC107051857",17.451372,46.921555,1.426910362,{"v":5.14e-164,"d":"5.14E-164"},{"v":4.87e-163,"d":"4.87E-163"},"up","LOC107051857","-","-","-","-"]
["BBS9",2.383687,6.4048,1.425958712,{"v":4.69e-66,"d":"4.69E-66"},{"v":2.45e-65,"d":"2.45E-65"},"up","BBS9","-","GO:0034464","-","KOG3679-Predicted coiled-coil protein[R]"]
["LOC771190",2.361627,6.341397,1.425019578,{"v":1.13e-06,"d":"1.13E-06"},{"v":2.12e-06,"d":"2.12E-06"},"up","LOC771190","-","-","-","-"]
["MGAM",3.725412,9.997375,1.424149353,{"v":3.83e-95,"d":"3.83E-95"},{"v":2.48e-94,"d":"2.48E-94"},"up","MGAM","-","GO:0003824;GO:0004553;GO:0005975;GO:0016020;GO:0016021;GO:0030246","-","-"]
["GYG1",49.996479,134.085022,1.423249688,0,0,"up","GYG1","glycogenin 1","GO:0016740;GO:0016757","-","KOG1950-Glycosyl transferase, family 8 - glycogenin[G]"]
["SLC6A8",70.925224,190.161911,1.4228576,0,0,"up","SLC6A8","-","GO:0005328;GO:0006836;GO:0015293;GO:0016020;GO:0016021;GO:0055085","-","-"]
["MYH10",22.013039,58.98011,1.421870184,0,0,"up","MYH10","myosin, heavy chain 10, non-muscle","GO:0000166;GO:0000281;GO:0001725;GO:0001764;GO:0001778;GO:0003279;GO:0003774;GO:0003779;GO:0005524;GO:0005737;GO:0005819;GO:0005886;GO:0005903;GO:0005938;GO:0006887;GO:0006930;GO:0007097;GO:0007409;GO:0007411;GO:0007420;GO:0007507;GO:0007512;GO:0008283;GO:0008360;GO:0016459;GO:0016460;GO:0021592;GO:0021670;GO:0021678;GO:0021680;GO:0030036;GO:0030239;GO:0030424;GO:0030426;GO:0031175;GO:0031594;GO:0035904;GO:0043005;GO:0043025;GO:0043197;GO:0050885;GO:0051015;GO:0055003;GO:0055015;GO:0060041;GO:0060976;GO:0098974;GO:0098978","K10352-ko04530 Tight junction","KOG0161-Myosin class II heavy chain[Z]"]
["MLLT11",12.879553,34.488026,1.421013031,{"v":1.86e-80,"d":"1.86E-80"},{"v":1.09e-79,"d":"1.09E-79"},"up","MLLT11","-","GO:0005622;GO:0005654;GO:0005737;GO:0005829;GO:0043065;GO:0045893;GO:0051901;GO:0090200;GO:0097190;GO:0097191;GO:0097193","K11421-ko00310 Lysine degradation;ko04550 Signaling pathways regulating pluripotency of stem cells","-"]
["QSOX2",12.163517,32.444229,1.415401448,{"v":7.73e-280,"d":"7.73E-280"},{"v":1.11e-278,"d":"1.11E-278"},"up","QSOX2","-","GO:0003756;GO:0005615;GO:0005623;GO:0005654;GO:0005794;GO:0016020;GO:0016021;GO:0016491;GO:0016971;GO:0016972;GO:0030173;GO:0045454;GO:0055114","-","KOG1731-FAD-dependent sulfhydryl oxidase/quiescin and related proteins[D]"]
["CCDC141",2.684091,7.155703,1.414659924,{"v":1.37e-87,"d":"1.37E-87"},{"v":8.45e-87,"d":"8.45E-87"},"up","CCDC141","-","GO:0005737;GO:0005813;GO:0016020;GO:0016021;GO:0021799;GO:0051642","-","-"]
["GPC4",45.154129,120.337601,1.414157679,0,0,"up","GPC4","-","GO:0005886;GO:0009897;GO:0009966;GO:0016020;GO:0031225;GO:0045202;GO:0046658;GO:0062023;GO:0098978;GO:0099560","K08110-ko04310 Wnt signaling pathway","KOG3821-Heparin sulfate cell surface proteoglycan[T]"]
["IFT52",20.152786,53.683575,1.413501453,{"v":1.59e-283,"d":"1.59E-283"},{"v":2.28e-282,"d":"2.28E-282"},"up","IFT52","intraflagellar transport 52","GO:0001841;GO:0001947;GO:0005813;GO:0005814;GO:0005929;GO:0007224;GO:0007368;GO:0009953;GO:0030992;GO:0032391;GO:0035720;GO:0042733;GO:0044292;GO:0050680;GO:0060271;GO:0070613;GO:0097542;GO:0097546;GO:1905515","-","KOG3861-Sensory cilia assembly protein[W]"]
["NCALD",6.807373,18.129225,1.413147186,{"v":9.22e-28,"d":"9.22E-28"},{"v":3.1e-27,"d":"3.10E-27"},"up","NCALD","neurocalcin delta","GO:0003073;GO:0003779;GO:0005509;GO:0005622;GO:0015631;GO:0019722;GO:0030276;GO:0046872","-","KOG0044-Ca2+ sensor (EF-Hand superfamily)[T]"]
["PCCA",8.091915,21.518906,1.411051664,{"v":6.45e-155,"d":"6.45E-155"},{"v":5.85e-154,"d":"5.85E-154"},"up","PCCA","-","GO:0000166;GO:0004658;GO:0005524;GO:0016874;GO:0019899;GO:0046872","K01965-ko01200 Carbon metabolism;ko00630 Glyoxylate and dicarboxylate metabolism;ko00640 Propanoate metabolism;ko00280 Valine, leucine and isoleucine degradation","KOG0238-3-Methylcrotonyl-CoA carboxylase, biotin-containing subunit/Propionyl-CoA carboxylase, alpha chain/Acetyl-CoA carboxylase, biotin carboxylase subunit[IE]"]
["ACSL1",47.66325,126.472641,1.407876097,0,0,"up","ACSL1","acyl-CoA synthetase long-chain family member 1","GO:0003824;GO:0008152;GO:0001676;GO:0003824;GO:0004467;GO:0005739;GO:0008152;GO:0008610;GO:0033211;GO:0044539;GO:0071902;GO:0120162","K01897-ko01212 Fatty acid metabolism;ko00061 Fatty acid biosynthesis;ko00071 Fatty acid degradation;ko04146 Peroxisome;ko02024 Quorum sensing;ko04920 Adipocytokine signaling pathway;ko03320 PPAR signaling pathway","KOG1256-Long-chain acyl-CoA synthetases (AMP-forming)[I]"]
["HIST1H4I",11.333073,30.069895,1.407780725,{"v":2.24e-33,"d":"2.24E-33"},{"v":8.25e-33,"d":"8.25E-33"},"up","HIST1H4I","-","-","-","-"]
["DACT2",7.086066,18.767511,1.405180521,{"v":4.89e-113,"d":"4.89E-113"},{"v":3.57e-112,"d":"3.57E-112"},"up","DACT2","-","GO:0002244;GO:0003382;GO:0005080;GO:0005737;GO:0007162;GO:0008013;GO:0008134;GO:0030111;GO:0043588;GO:0051018;GO:0070097;GO:0072061;GO:1900108","-","-"]
["CZH5ORF42",2.51936,6.670986,1.404842725,{"v":1.6e-105,"d":"1.60E-105"},{"v":1.11e-104,"d":"1.11E-104"},"up","CZH5ORF42","-","-","-","-"]
["AK1",195.755676,517.687134,1.403026324,0,0,"up","AK1","adenylate kinase 1","GO:0000166;GO:0004017;GO:0004550;GO:0005524;GO:0005737;GO:0005829;GO:0005886;GO:0006139;GO:0006165;GO:0006172;GO:0007050;GO:0009142;GO:0016301;GO:0016310;GO:0016740;GO:0019205;GO:0036126;GO:0046033;GO:0046034;GO:0046940","K00939-ko00230 Purine metabolism","KOG3079-Uridylate kinase/adenylate kinase[F]"]
["LOC112530237",13.543893,35.814941,1.402919085,{"v":5.49e-13,"d":"5.49E-13"},{"v":1.33e-12,"d":"1.33E-12"},"up","LOC112530237","-","-","-","-"]
["LOC101750687",2.412605,6.376607,1.402197237,{"v":1.33e-123,"d":"1.33E-123"},{"v":1.03e-122,"d":"1.03E-122"},"up","LOC101750687","-","-","-","-"]
["HBA1",399.228943,1054.6073,1.401417667,0,0,"up","HBA1","hemoglobin subunit alpha 1","GO:0005344;GO:0005506;GO:0005833;GO:0015671;GO:0019825;GO:0020037;GO:0046872","-","-"]
["LAPTM4B",17.752041,46.827251,1.399363442,{"v":1.64e-204,"d":"1.64E-204"},{"v":1.85e-203,"d":"1.85E-203"},"up","LAPTM4B","-","GO:0005764;GO:0005765;GO:0005768;GO:0005769;GO:0005886;GO:0007032;GO:0016020;GO:0016021;GO:0019900;GO:0031625;GO:0031902;GO:0032509;GO:0032585;GO:0032911;GO:0042995;GO:0097001;GO:0097213;GO:0097487;GO:1902936;GO:1905166;GO:1905671","K12387-ko04142 Lysosome","-"]
["LOC112532893",2.585582,6.819845,1.399249891,{"v":9.41e-31,"d":"9.41E-31"},{"v":3.33e-30,"d":"3.33E-30"},"up","LOC112532893","-","-","-","-"]
["CAT",65.662651,173.103836,1.398492793,0,0,"up","CAT","catalase","GO:0000302;GO:0004046;GO:0004096;GO:0004601;GO:0005102;GO:0005777;GO:0005778;GO:0006641;GO:0006979;GO:0008203;GO:0009060;GO:0009650;GO:0014068;GO:0016209;GO:0016491;GO:0016684;GO:0019899;GO:0020027;GO:0020037;GO:0032088;GO:0042744;GO:0042802;GO:0042803;GO:0043066;GO:0043231;GO:0046872;GO:0050661;GO:0051092;GO:0051262;GO:0051289;GO:0055114;GO:0098869;GO:0004096;GO:0006979;GO:0020037;GO:0055114;GO:0098869","K03781-ko01200 Carbon metabolism;ko00630 Glyoxylate and dicarboxylate metabolism;ko00380 Tryptophan metabolism;ko04011 MAPK signaling pathway - yeast;ko04068 FoxO signaling pathway;ko04146 Peroxisome;ko04211 Longevity regulating pathway - mammal;ko04212 Longevity regulating pathway - worm;ko04213 Longevity regulating pathway - multiple species;ko05014 Amyotrophic lateral sclerosis (ALS)","KOG0047-Catalase[P]"]
["TMEM61",2.163836,5.701708,1.397802997,{"v":1.29e-11,"d":"1.29E-11"},{"v":2.99e-11,"d":"2.99E-11"},"up","TMEM61","-","GO:0016020;GO:0016021","-","-"]
["HS1BP3",2.219723,5.844683,1.396745126,{"v":3.54e-55,"d":"3.54E-55"},{"v":1.68e-54,"d":"1.68E-54"},"up","HS1BP3","-","GO:0005739;GO:0005783;GO:0035091;GO:0042981","-","-"]
["GADD45B",60.465816,159.06279,1.395404723,{"v":8.24e-270,"d":"8.24E-270"},{"v":1.15e-268,"d":"1.15E-268"},"up","GADD45B","-","GO:0000185;GO:0000186;GO:0005634;GO:0005737;GO:0006469;GO:0006950;GO:0043065;GO:0046330;GO:0051726;GO:1900745","K04402-ko04010 MAPK signaling pathway;ko04068 FoxO signaling pathway;ko04110 Cell cycle;ko04210 Apoptosis;ko04115 p53 signaling pathway","-"]
["KLF15",18.804947,49.42487,1.394124931,{"v":5.68e-257,"d":"5.68E-257"},{"v":7.62e-256,"d":"7.62E-256"},"up","KLF15","-","GO:0003676;GO:0003677;GO:0003700;GO:0005634;GO:0010001;GO:0010468;GO:0014898;GO:0044212;GO:0045893;GO:0045944;GO:0046326;GO:0072112;GO:2000757;GO:2001275","-","KOG2462-C2H2-type Zn-finger protein[K]"]
["LOC101747821",6.078235,15.965848,1.393264822,{"v":2.77e-110,"d":"2.77E-110"},{"v":1.99e-109,"d":"1.99E-109"},"up","LOC101747821","-","GO:0016020;GO:0016021","-","-"]
["RAP1GAP1",2.407912,6.323418,1.392921922,{"v":3.45e-26,"d":"3.45E-26"},{"v":1.13e-25,"d":"1.13E-25"},"up","RAP1GAP1","RAP1 GTPase activating protein 1","GO:0005096;GO:0030695;GO:0043547;GO:0050790;GO:0051056","-","KOG3686-Rap1-GTPase-activating protein (Rap1GAP)[T]"]
["KIAA0556",4.731044,12.421658,1.392627269,{"v":7.34e-121,"d":"7.34E-121"},{"v":5.6e-120,"d":"5.60E-120"},"up","KIAA0556","-","-","-","-"]
["MCU",33.387634,87.620209,1.391949795,0,0,"up","MCU","-","GO:0005262;GO:0005739;GO:0005743;GO:0006851;GO:0015292;GO:0016020;GO:0016021;GO:0019722;GO:0031305;GO:0032024;GO:0034704;GO:0036444;GO:0042593;GO:0042802;GO:0051259;GO:0051560;GO:0051561;GO:1990246","-","KOG2966-Uncharacterized conserved protein[R]"]
["LOC419389",9.26093,24.29962,1.391704769,{"v":1.13e-33,"d":"1.13E-33"},{"v":4.17e-33,"d":"4.17E-33"},"up","LOC419389","-","-","-","-"]
["ACOT11",12.446257,32.627319,1.390368504,{"v":2.46e-133,"d":"2.46E-133"},{"v":2.02e-132,"d":"2.02E-132"},"up","ACOT11","-","GO:0005829;GO:0006631;GO:0006637;GO:0008289;GO:0047617","-","KOG2763-Acyl-CoA thioesterase[I]"]
["ELP2",3.726003,9.742299,1.386633426,{"v":9.81e-42,"d":"9.81E-42"},{"v":4.04e-41,"d":"4.04E-41"},"up","ELP2","-","GO:0000993;GO:0002098;GO:0005829;GO:0008023;GO:0019901;GO:0033588;GO:0046425","-","KOG1063-RNA polymerase II elongator complex, subunit ELP2, WD repeat superfamily[BK]"]
["IFT81",7.047498,18.416519,1.385817328,{"v":3.07e-108,"d":"3.07E-108"},{"v":2.17e-107,"d":"2.17E-107"},"up","IFT81","intraflagellar transport 81","GO:0005813;GO:0005929;GO:0007283;GO:0008589;GO:0015631;GO:0030992;GO:0035735;GO:0036064;GO:0042073;GO:0060271;GO:0097225;GO:0097228","-","-"]
["HSD17B11",19.640926,51.291603,1.384859711,{"v":3.81e-120,"d":"3.81E-120"},{"v":2.89e-119,"d":"2.89E-119"},"up","HSD17B11","-","-","-","-"]
["RNF19B",4.289587,11.201459,1.384776,{"v":4.45e-48,"d":"4.45E-48"},{"v":1.97e-47,"d":"1.97E-47"},"up","RNF19B","-","GO:0004842;GO:0005829;GO:0016020;GO:0016021;GO:0016567;GO:0016740;GO:0046872","-","-"]
["IDH3A",53.5284,139.739059,1.384358895,0,0,"up","IDH3A","isocitrate dehydrogenase 3 (NAD( )) alpha","GO:0000287;GO:0004449;GO:0005739;GO:0006099;GO:0016616;GO:0043209;GO:0051287;GO:0055114","K00030-ko01200 Carbon metabolism;ko01210 2-Oxocarboxylic acid metabolism;ko01230 Biosynthesis of amino acids;ko00020 Citrate cycle (TCA cycle)","KOG0785-Isocitrate dehydrogenase, alpha subunit[E]"]
["COMT",21.047646,54.860661,1.382113116,{"v":1.45e-164,"d":"1.45E-164"},{"v":1.38e-163,"d":"1.38E-163"},"up","COMT","-","GO:0000287;GO:0006584;GO:0008171;GO:0009712;GO:0016020;GO:0016021;GO:0016036;GO:0016206;GO:0032259;GO:0042135;GO:0042417;GO:0042420;GO:0042424;GO:0043231;GO:0046872","K00545-ko00140 Steroid hormone biosynthesis;ko00350 Tyrosine metabolism;ko00965 Betalain biosynthesis;ko04728 Dopaminergic synapse","KOG1663-O-methyltransferase[Q]"]
["BBS10",4.760173,12.400388,1.381299351,{"v":7.82e-42,"d":"7.82E-42"},{"v":3.22e-41,"d":"3.22E-41"},"up","BBS10","-","GO:0000166;GO:0001103;GO:0001895;GO:0005524;GO:0043254;GO:0045494;GO:0051131;GO:1905515","-","-"]
["LOC422177",4.073137,10.590455,1.378552328,{"v":6.66e-34,"d":"6.66E-34"},{"v":2.46e-33,"d":"2.46E-33"},"up","LOC422177","-","-","-","-"]
["LOXL3",14.641196,38.066593,1.378492045,{"v":4.59e-192,"d":"4.59E-192"},{"v":4.88e-191,"d":"4.88E-191"},"up","LOXL3","-","GO:0001837;GO:0001968;GO:0004720;GO:0005044;GO:0005507;GO:0005576;GO:0005615;GO:0005634;GO:0005737;GO:0006898;GO:0006954;GO:0016020;GO:0016641;GO:0018057;GO:0021510;GO:0030324;GO:0045892;GO:0055114;GO:0060021;GO:0061053;GO:1905590;GO:2000329;GO:2001046","-","-"]
["C28H19ORF44",6.94997,18.035738,1.375779802,{"v":7.53e-71,"d":"7.53E-71"},{"v":4.09e-70,"d":"4.09E-70"},"up","C28H19ORF44","-","-","-","-"]
["MTCP1",7.485871,19.425322,1.375696421,{"v":3.73e-165,"d":"3.73E-165"},{"v":3.56e-164,"d":"3.56E-164"},"up","MTCP1","-","-","-","-"]
["PLIN2",43.625465,113.188492,1.375484871,0,0,"up","PLIN2","perilipin 2","GO:0005634;GO:0005737;GO:0005811;GO:0005829;GO:0005886;GO:0015909;GO:0019915","K17284-ko03320 PPAR signaling pathway","-"]
["GRB10",14.759704,38.281914,1.374999174,0,0,"up","GRB10","growth factor receptor bound protein 10","GO:0005070;GO:0005158;GO:0007165;GO:0009967;GO:0030178;GO:0030949;GO:0032991;GO:0042326;GO:0046325;GO:0046627;GO:0048009;GO:0120162","K20064-ko04150 mTOR signaling pathway","KOG3751-Growth factor receptor-bound proteins (GRB7, GRB10, GRB14)[T]"]
["TNFRSF25",3.960588,10.265441,1.374009069,{"v":7.86e-34,"d":"7.86E-34"},{"v":2.9e-33,"d":"2.90E-33"},"up","TNFRSF25","-","-","K05160-ko04060 Cytokine-cytokine receptor interaction","-"]
["LPCAT2",12.968088,33.56522,1.372001312,{"v":3.45e-157,"d":"3.45E-157"},{"v":3.16e-156,"d":"3.16E-156"},"up","LPCAT2","lysophosphatidylcholine acyltransferase 2","GO:0005509;GO:0005783;GO:0005811;GO:0008152;GO:0016020;GO:0016021;GO:0016746;GO:0036151;GO:0047184","K13510-ko00564 Glycerophospholipid metabolism;ko00565 Ether lipid metabolism","[KOG4666-Predicted phosphate acyltransferase, contains PlsC domain[I], KOG0037-Ca2+-binding protein, EF-Hand protein superfamily[T]]"]
["ACSBG2",20.184311,52.215649,1.371247906,{"v":6.09e-291,"d":"6.09E-291"},{"v":9e-290,"d":"9.00E-290"},"up","ACSBG2","acyl-CoA synthetase bubblegum family member 2","GO:0003824;GO:0008152;GO:0000166;GO:0001676;GO:0003824;GO:0004467;GO:0005524;GO:0005737;GO:0006629;GO:0006631;GO:0008152;GO:0016874;GO:0102391","K15013-ko01212 Fatty acid metabolism;ko00061 Fatty acid biosynthesis;ko00071 Fatty acid degradation;ko04920 Adipocytokine signaling pathway;ko03320 PPAR signaling pathway","KOG1256-Long-chain acyl-CoA synthetases (AMP-forming)[I]"]
["PCDH19",3.445076,8.911988,1.37121148,{"v":3.12e-186,"d":"3.12E-186"},{"v":3.24e-185,"d":"3.24E-185"},"up","PCDH19","protocadherin 19","GO:0005509;GO:0005886;GO:0005887;GO:0007155;GO:0007156;GO:0007267;GO:0007399;GO:0007420;GO:0016020;GO:0016021","-","-"]
["PRDX6",236.736313,611.723816,1.369599427,0,0,"up","PRDX6","peroxiredoxin 6","GO:0004602;GO:0005615;GO:0005634;GO:0005737;GO:0006979;GO:0016209;GO:0016491;GO:0031625;GO:0042803;GO:0045454;GO:0046475;GO:0047499;GO:0048026;GO:0048471;GO:0051920;GO:0055114;GO:0098869;GO:0003824;GO:0004601;GO:0004623;GO:0005615;GO:0005737;GO:0005764;GO:0006629;GO:0008152;GO:0016042;GO:0016209;GO:0016491;GO:0016787;GO:0045454;GO:0051920;GO:0055114;GO:0098869;GO:0102567;GO:0102568","-","KOG0854-Alkyl hydroperoxide reductase, thiol specific antioxidant and related enzymes[O]"]
["CCDC66",6.158575,15.902491,1.368584293,{"v":1.99e-76,"d":"1.99E-76"},{"v":1.13e-75,"d":"1.13E-75"},"up","CCDC66","-","GO:0001578;GO:0001917;GO:0005813;GO:0005874;GO:0005929;GO:0008017;GO:0034451;GO:0036064;GO:0042803;GO:0046548;GO:0050908;GO:0060060;GO:0060271;GO:1903564","-","-"]
["CIDEC",4.847292,12.498549,1.366509719,{"v":2.59e-18,"d":"2.59E-18"},{"v":7.24e-18,"d":"7.24E-18"},"up","CIDEC","cell death inducing DFFA like effector c","GO:0005622;GO:0005811;GO:0006915;GO:0042981","-","-"]
["DHRS7B",15.207604,39.182072,1.365400821,{"v":2.26e-143,"d":"2.26E-143"},{"v":1.94e-142,"d":"1.94E-142"},"up","DHRS7B","-","GO:0008611;GO:0016020;GO:0016021;GO:0016491;GO:0030223;GO:0055114","-","KOG1205-Predicted dehydrogenase[Q]"]
["NDUFAB1",120.810753,311.249146,1.365321008,0,0,"up","NDUFAB1","-","GO:0000035;GO:0000036;GO:0005654;GO:0005739;GO:0005747;GO:0005762;GO:0005829;GO:0006633;GO:0009245;GO:0009249;GO:0031177;GO:0032981","K03955-ko00190 Oxidative phosphorylation;ko05010 Alzheimer's disease;ko05012 Parkinson's disease;ko05016 Huntington's disease;ko04932 Non-alcoholic fatty liver disease (NAFLD)","KOG1748-Acyl carrier protein/NADH-ubiquinone oxidoreductase, NDUFAB1/SDAP subunit[CIQ]"]
["NUDT13",2.898017,7.465356,1.365145002,{"v":3.27e-27,"d":"3.27E-27"},{"v":1.09e-26,"d":"1.09E-26"},"up","NUDT13","-","GO:0016787;GO:0046872","-","KOG3084-NADH pyrophosphatase I of the Nudix family of hydrolases[L]"]
["LIPT2",5.317902,13.694977,1.364717747,{"v":1.45e-23,"d":"1.45E-23"},{"v":4.5e-23,"d":"4.50E-23"},"up","LIPT2","-","-","K03801-ko00785 Lipoic acid metabolism","KOG0325-Lipoyltransferase[CH]"]
["SLC16A7",7.67965,19.776621,1.364683484,0,0,"up","SLC16A7","solute carrier family 16 member 7","GO:0005887;GO:0008028;GO:0015129;GO:0015718;GO:0016020;GO:0016021;GO:0035873;GO:0050833;GO:0055085;GO:1901475","-","KOG2504-Monocarboxylate transporter[G]"]
["CGTL",2.599442,6.693793,1.364621972,{"v":1.88e-54,"d":"1.88E-54"},{"v":8.83e-54,"d":"8.83E-54"},"up","CGTL","-","GO:0005887;GO:0015179;GO:0015297;GO:0016020;GO:0016021;GO:0022857;GO:0055085;GO:1902475","-","-"]
["PITX2",28.342085,72.975189,1.364460147,{"v":6.1e-182,"d":"6.10E-182"},{"v":6.23e-181,"d":"6.23E-181"},"up","PITX2","paired like homeodomain 2","GO:0000976;GO:0000981;GO:0001102;GO:0001569;GO:0001570;GO:0001764;GO:0002074;GO:0003171;GO:0003253;GO:0003350;GO:0003677;GO:0003682;GO:0003700;GO:0003713;GO:0005634;GO:0005667;GO:0005737;GO:0006355;GO:0006357;GO:0007275;GO:0007368;GO:0007507;GO:0007519;GO:0007520;GO:0008134;GO:0009653;GO:0009887;GO:0016055;GO:0021763;GO:0021855;GO:0021983;GO:0030324;GO:0030334;GO:0031076;GO:0031490;GO:0035116;GO:0035886;GO:0035993;GO:0042127;GO:0043010;GO:0043388;GO:0043565;GO:0045893;GO:0045944;GO:0048536;GO:0048557;GO:0048738;GO:0055007;GO:0055009;GO:0055015;GO:0055123;GO:0060412;GO:0060460;GO:0060577;GO:0060578;GO:0061031;GO:0061072;GO:0061325;GO:0070986;GO:2000288;GO:0001947;GO:0003007;GO:0003677;GO:0003700;GO:0005634;GO:0006355;GO:0007275;GO:0007368;GO:0030326;GO:0032526;GO:0043565;GO:0045663;GO:0045944;GO:0048562;GO:0061184;GO:2000287;GO:2000288","K04686-ko04350 TGF-beta signaling pathway","KOG0486-Transcription factor PTX1, contains HOX domain[K]"]
["DRAM1",3.046881,7.840458,1.363604777,{"v":3.16e-28,"d":"3.16E-28"},{"v":1.07e-27,"d":"1.07E-27"},"up","DRAM1","-","GO:0005737;GO:0005764;GO:0010506;GO:0016020;GO:0016021","-","KOG4320-Uncharacterized conserved protein[S]"]
["CEP164",2.038975,5.246473,1.363503794,{"v":2.72e-98,"d":"2.72E-98"},{"v":1.81e-97,"d":"1.81E-97"},"up","CEP164","-","GO:0005654;GO:0005813;GO:0005814;GO:0043231;GO:0060271;GO:0097539","-","-"]
["LOC112532591",5.88913,15.120813,1.360409285,0.000472116,0.000752359,"up","LOC112532591","-","-","-","-"]
["EDN2",3.211886,8.225828,1.356740218,{"v":5.3e-35,"d":"5.30E-35"},{"v":1.99e-34,"d":"1.99E-34"},"up","EDN2","endothelin 2","GO:0001516;GO:0001659;GO:0002690;GO:0003100;GO:0005179;GO:0005576;GO:0005615;GO:0005622;GO:0005623;GO:0007204;GO:0008284;GO:0010460;GO:0010469;GO:0014824;GO:0014826;GO:0019221;GO:0019229;GO:0019722;GO:0030593;GO:0031708;GO:0042116;GO:0042310;GO:0045987;GO:0048016;GO:0048246;GO:0048286;GO:0060585;GO:0097009","K16367-ko04080 Neuroactive ligand-receptor interaction;ko04270 Vascular smooth muscle contraction","-"]
["TMEM53",9.444928,24.164799,1.355295291,{"v":1.92e-53,"d":"1.92E-53"},{"v":8.96e-53,"d":"8.96E-53"},"up","TMEM53","transmembrane protein 53","GO:0016020;GO:0016021","-","KOG2521-Uncharacterized conserved protein[S]"]
["ALDH1A3",62.147636,158.539337,1.351069429,0,0,"up","ALDH1A3","aldehyde dehydrogenase 1 family member A3","-","K00129-ko00010 Glycolysis / Gluconeogenesis;ko00340 Histidine metabolism;ko00350 Tyrosine metabolism;ko00360 Phenylalanine metabolism;ko00410 beta-Alanine metabolism;ko00980 Metabolism of xenobiotics by cytochrome P450;ko00982 Drug metabolism - cytochrome P450;ko05204 Chemical carcinogenesis","KOG2450-Aldehyde dehydrogenase[C]"]
["ASS1",65.117424,166.000549,1.350072479,0,0,"up","ASS1","argininosuccinate synthase 1","GO:0000050;GO:0000052;GO:0000053;GO:0004055;GO:0005524;GO:0005739;GO:0005829;GO:0006526;GO:0006531;GO:0007623;GO:0016597;GO:0042802;GO:0043209;GO:0045429;GO:0071499;GO:1903038;GO:0000050;GO:0000053;GO:0000166;GO:0004055;GO:0005524;GO:0005737;GO:0005829;GO:0006526;GO:0008652;GO:0016874","K01940-ko01230 Biosynthesis of amino acids;ko00250 Alanine, aspartate and glutamate metabolism;ko00220 Arginine biosynthesis","KOG1706-Argininosuccinate synthase[E]"]
["CSPP1",6.399148,16.312471,1.350023598,{"v":2.11e-100,"d":"2.11E-100"},{"v":1.42e-99,"d":"1.42E-99"},"up","CSPP1","-","-","-","-"]
["MIR1778",21.867386,55.738621,1.349896537,{"v":1.32e-07,"d":"1.32E-07"},{"v":2.6e-07,"d":"2.60E-07"},"up","MIR1778","microRNA 1778","-","-","-"]
["NME7",33.432053,85.150162,1.348777324,{"v":3.52e-200,"d":"3.52E-200"},{"v":3.87e-199,"d":"3.87E-199"},"up","NME7","-","GO:0000166;GO:0004550;GO:0005524;GO:0005813;GO:0006165;GO:0006183;GO:0006228;GO:0006241","K00940-ko00230 Purine metabolism;ko00240 Pyrimidine metabolism","KOG0888-Nucleoside diphosphate kinase[F]"]
["CFAP36",13.276212,33.781544,1.347391696,{"v":2.69e-100,"d":"2.69E-100"},{"v":1.81e-99,"d":"1.81E-99"},"up","CFAP36","cilia and flagella associated protein 36","GO:0035869;GO:0047485;GO:0097546","-","KOG4511-Uncharacterized conserved protein[S]"]
["WDR60",4.907611,12.479662,1.346486057,{"v":4.89e-79,"d":"4.89E-79"},{"v":2.83e-78,"d":"2.83E-78"},"up","WDR60","-","-","-","KOG1587-Cytoplasmic dynein intermediate chain[Z]"]
["PDE3B",4.934564,12.540696,1.345622895,{"v":1.18e-77,"d":"1.18E-77"},{"v":6.74e-77,"d":"6.74E-77"},"up","PDE3B","phosphodiesterase 3B","GO:0004114;GO:0007162;GO:0007165;GO:0008081;GO:0016020;GO:0016021;GO:0016525;GO:0016787;GO:0032045;GO:0046872;GO:0050995","K13296-ko00230 Purine metabolism;ko04024 cAMP signaling pathway;ko04022 cGMP - PKG signaling pathway;ko04910 Insulin signaling pathway;ko04922 Glucagon signaling pathway;ko04923 Regulation of lipolysis in adipocyte;ko04914 Progesterone-mediated oocyte maturation;ko04924 Renin secretion;ko05032 Morphine addiction","KOG3689-Cyclic nucleotide phosphodiesterase[T]"]
["FRMD3",15.001934,38.087433,1.344166557,{"v":7.17e-259,"d":"7.17E-259"},{"v":9.68e-258,"d":"9.68E-258"},"up","FRMD3","-","GO:0005200;GO:0005856;GO:0016020;GO:0016021;GO:0031032","-","KOG3530-FERM domain protein EHM2[R]"]
["BF1",104.207123,264.493225,1.343776873,0,0,"up","BF1","MHC BF1 class I","GO:0005886;GO:0016020;GO:0016021","K06751-ko04514 Cell adhesion molecules (CAMs);ko04144 Endocytosis;ko04145 Phagosome;ko04650 Natural killer cell mediated cytotoxicity;ko04612 Antigen processing and presentation;ko05203 Viral carcinogenesis;ko05320 Autoimmune thyroid disease;ko05330 Allograft rejection;ko05332 Graft-versus-host disease;ko05416 Viral myocarditis;ko04940 Type I diabetes mellitus;ko05166 HTLV-I infection;ko05168 Herpes simplex infection;ko05169 Epstein-Barr virus infection","-"]
["NDUFV3",152.490051,386.996643,1.343605933,0,0,"up","NDUFV3","NADH:ubiquinone oxidoreductase subunit V3","GO:0005739;GO:0005747","K03944-ko00190 Oxidative phosphorylation;ko05010 Alzheimer's disease;ko05012 Parkinson's disease;ko05016 Huntington's disease;ko04932 Non-alcoholic fatty liver disease (NAFLD)","-"]
["BTN1",6.413564,16.26861,1.342892805,{"v":2.05e-69,"d":"2.05E-69"},{"v":1.1e-68,"d":"1.10E-68"},"up","BTN1","-","-","-","-"]
["PIH1D2",4.802595,12.142323,1.338158399,{"v":9.03e-45,"d":"9.03E-45"},{"v":3.86e-44,"d":"3.86E-44"},"up","PIH1D2","-","-","-","KOG4356-Uncharacterized conserved protein[S]"]
["LOC415756",3.568953,9.022965,1.338100687,{"v":1.23e-11,"d":"1.23E-11"},{"v":2.86e-11,"d":"2.86E-11"},"up","LOC415756","uncharacterized LOC415756","GO:0016020;GO:0016021","-","-"]
["DZIP1",8.030937,20.290022,1.337130202,{"v":5.32e-106,"d":"5.32E-106"},{"v":3.7e-105,"d":"3.70E-105"},"up","DZIP1","-","GO:0003676;GO:0005634;GO:0005654;GO:0005737;GO:0005814;GO:0005815;GO:0005829;GO:0007224;GO:0034451;GO:0036064;GO:0043393;GO:0044782;GO:0045184;GO:0045724;GO:0051220;GO:0060271;GO:0061512;GO:0097539","-","-"]
["MTHFD1L",5.116642,12.911374,1.335373337,{"v":8.96e-109,"d":"8.96E-109"},{"v":6.35e-108,"d":"6.35E-108"},"up","MTHFD1L","-","GO:0001843;GO:0004329;GO:0004477;GO:0004488;GO:0005524;GO:0005737;GO:0005739;GO:0009113;GO:0009257;GO:0048702;GO:0048703;GO:0055114","K13402-ko00670 One carbon pool by folate","KOG4230-C1-tetrahydrofolate synthase[H]"]
["MPZ",33.124744,83.556374,1.334840582,{"v":5.71e-159,"d":"5.71E-159"},{"v":5.29e-158,"d":"5.29E-158"},"up","MPZ","myelin protein zero","GO:0005886;GO:0005887;GO:0016020;GO:0016021;GO:0042552;GO:0043209;GO:0098742;GO:0098743","K06770-ko04514 Cell adhesion molecules (CAMs)","-"]
["CBARP",5.482109,13.824889,1.334464979,{"v":5.49e-64,"d":"5.49E-64"},{"v":2.82e-63,"d":"2.82E-63"},"up","CBARP","-","-","-","-"]
["CEP83",4.130168,10.414991,1.334389221,{"v":1.84e-49,"d":"1.84E-49"},{"v":8.25e-49,"d":"8.25E-49"},"up","CEP83","-","GO:0005814;GO:0048278;GO:0051660;GO:0060271","-","-"]
["HRH1",8.756464,22.070309,1.333686519,{"v":5.35e-156,"d":"5.35E-156"},{"v":4.88e-155,"d":"4.88E-155"},"up","HRH1","-","GO:0004930;GO:0004969;GO:0005829;GO:0005886;GO:0006954;GO:0007165;GO:0007186;GO:0007200;GO:0007613;GO:0008542;GO:0016020;GO:0016021;GO:0019229;GO:0043114;GO:0045907;GO:0048167;GO:0048245;GO:0050804","K04149-ko04020 Calcium signaling pathway;ko04080 Neuroactive ligand-receptor interaction;ko04750 Inflammatory mediator regulation of TRP channels","KOG4220-Muscarinic acetylcholine receptor[T]"]
["ECSIT",18.923775,47.596619,1.330659183,{"v":1.43e-115,"d":"1.43E-115"},{"v":1.06e-114,"d":"1.06E-114"},"up","ECSIT","-","GO:0005634;GO:0005654;GO:0005737;GO:0005739;GO:0005829;GO:0016651;GO:0051341;GO:0055114","K04405-ko04010 MAPK signaling pathway","KOG3941-Intermediate in Toll signal transduction pathway (ECSIT)[T]"]
["FBLN7",35.185314,88.257462,1.326744873,0,0,"up","FBLN7","fibulin 7","GO:0005509","-","KOG1217-Fibrillins and related proteins containing Ca2+-binding EGF-like domains[T]"]
["TTLL9",4.71279,11.809256,1.325264774,{"v":3.45e-36,"d":"3.45E-36"},{"v":1.32e-35,"d":"1.32E-35"},"up","TTLL9","-","GO:0006464","-","KOG2157-Predicted tubulin-tyrosine ligase[O]"]
["RAD23A",95.656639,239.428284,1.323656583,0,0,"up","RAD23A","-","GO:0003684;GO:0005634;GO:0005654;GO:0005737;GO:0005815;GO:0005829;GO:0006289;GO:0006974;GO:0019900;GO:0031593;GO:0031648;GO:0032434;GO:0032436;GO:0032991;GO:0043161;GO:0043231;GO:0045070;GO:0045787;GO:1990381","K10839-ko04141 Protein processing in endoplasmic reticulum;ko03420 Nucleotide excision repair","KOG0011-Nucleotide excision repair factor NEF2, RAD23 component[L]"]
["EXFABP",78.624329,196.339615,1.320303587,{"v":2.25e-201,"d":"2.25E-201"},{"v":2.49e-200,"d":"2.49E-200"},"up","EXFABP","extracellular fatty acid-binding protein","GO:0002062;GO:0002376;GO:0003415;GO:0005504;GO:0005576;GO:0005615;GO:0005623;GO:0006915;GO:0006953;GO:0006954;GO:0007507;GO:0008283;GO:0008284;GO:0009636;GO:0009792;GO:0010831;GO:0015908;GO:0015909;GO:0030154;GO:0032332;GO:0032496;GO:0034097;GO:0036094;GO:0042493;GO:0042742;GO:0043066;GO:0044255;GO:0045087;GO:0045663;GO:0048747;GO:0050544;GO:0051412;GO:0055089;GO:0070538;GO:0070539;GO:0070540;GO:0070543;GO:0071399","-","-"]
["EXTL1",18.364456,45.826591,1.319268808,{"v":1.2e-199,"d":"1.20E-199"},{"v":1.31e-198,"d":"1.31E-198"},"up","EXTL1","-","GO:0006486;GO:0016021;GO:0016757","K02366-ko00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin","-"]
["CDKN1C",53.938084,134.535263,1.318608187,{"v":4.75e-292,"d":"4.75E-292"},{"v":7.07e-291,"d":"7.07E-291"},"up","CDKN1C","-","-","K09993-ko04110 Cell cycle","-"]
["FKBP9",80.528267,200.838699,1.318470093,0,0,"up","FKBP9","FK506 binding protein 9","GO:0000413;GO:0003755;GO:0005509;GO:0005783;GO:0006457;GO:0016853","-","KOG0549-FKBP-type peptidyl-prolyl cis-trans isomerase[O]"]
["GPR146",21.039238,52.431587,1.31735376,{"v":3.38e-249,"d":"3.38E-249"},{"v":4.43e-248,"d":"4.43E-248"},"up","GPR146","G protein-coupled receptor 146","GO:0004930;GO:0007186;GO:0016020;GO:0016021","-","-"]
["AP5S1",25.63493,63.82056,1.31591031,{"v":2e-52,"d":"2.00E-52"},{"v":9.22e-52,"d":"9.22E-52"},"up","AP5S1","-","GO:0000724;GO:0005654;GO:0005764;GO:0005770;GO:0005829;GO:0016197;GO:0030119","-","-"]
["VEGFRKDRL",27.254341,67.799095,1.314779979,0,0,"up","VEGFRKDRL","-","GO:0000166;GO:0004672;GO:0004713;GO:0004714;GO:0005021;GO:0005524;GO:0005887;GO:0006468;GO:0007169;GO:0016020;GO:0016021;GO:0016301;GO:0016310;GO:0016740;GO:0018108;GO:0038084;GO:0048010","K05096-ko04014 Ras signaling pathway;ko04015 Rap1 signaling pathway;ko04066 HIF-1 signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04060 Cytokine-cytokine receptor interaction;ko04144 Endocytosis;ko04510 Focal adhesion;ko05202 Transcriptional misregulation in cancers;ko05323 Rheumatoid arthritis","-"]
["LRRC23",3.36424,8.366304,1.314309792,{"v":3.84e-20,"d":"3.84E-20"},{"v":1.11e-19,"d":"1.11E-19"},"up","LRRC23","-","-","-","-"]
["FOLH1",4.653244,11.571186,1.314227998,{"v":5.79e-54,"d":"5.79E-54"},{"v":2.71e-53,"d":"2.71E-53"},"up","FOLH1","-","GO:0004180;GO:0004181;GO:0005886;GO:0005887;GO:0006508;GO:0006760;GO:0008233;GO:0009986;GO:0016020;GO:0016021;GO:0016805;GO:0035609;GO:1904492;GO:1904493","K14592-ko00250 Alanine, aspartate and glutamate metabolism;ko04977 Vitamin digestion and absorption","KOG2195-Transferrin receptor and related proteins containing the protease-associated (PA) domain[OPR]"]
["TM6SF1",16.099678,40.022354,1.313774191,{"v":2.2e-138,"d":"2.20E-138"},{"v":1.84e-137,"d":"1.84E-137"},"up","TM6SF1","transmembrane 6 superfamily member 1","GO:0005765;GO:0016020;GO:0016021","-","-"]
["MECOM",12.252539,30.457027,1.313694384,{"v":7.31e-179,"d":"7.31E-179"},{"v":7.36e-178,"d":"7.36E-178"},"up","MECOM","-","GO:0000118;GO:0003676;GO:0003700;GO:0005634;GO:0006355;GO:0016607;GO:0043069;GO:0045892;GO:0045893;GO:0046329;GO:0051726","K04462-ko04010 MAPK signaling pathway;ko05200 Pathways in cancer;ko05220 Chronic myeloid leukemia","[KOG2461-Transcription factor BLIMP-1/PRDI-BF1, contains C2H2-type Zn-finger and SET domains[K], KOG2462-C2H2-type Zn-finger protein[K]]"]
["PLACL2",13.39025,33.272614,1.313152317,{"v":3.99e-27,"d":"3.99E-27"},{"v":1.33e-26,"d":"1.33E-26"},"up","PLACL2","-","GO:0016020;GO:0016021","-","-"]
["GPRC5B",11.174667,27.731825,1.311310721,{"v":1.91e-200,"d":"1.91E-200"},{"v":2.11e-199,"d":"2.11E-199"},"up","GPRC5B","-","GO:0004930;GO:0005634;GO:0005730;GO:0005829;GO:0007186;GO:0016020;GO:0016021;GO:0030295;GO:0032147;GO:0043231;GO:0070062","-","KOG1056-Glutamate-gated metabotropic ion channel receptor subunit GRM2 and related subunits, G-protein coupled receptor superfamily[PT]"]
["LOC112530576",2.365791,5.869231,1.310848863,{"v":5.56e-19,"d":"5.56E-19"},{"v":1.58e-18,"d":"1.58E-18"},"up","LOC112530576","-","-","-","-"]
["COQ7",23.437458,58.135578,1.310605234,{"v":5.48e-36,"d":"5.48E-36"},{"v":2.09e-35,"d":"2.09E-35"},"up","COQ7","coenzyme Q7, hydroxylase","GO:0004497;GO:0005634;GO:0005739;GO:0005743;GO:0006744;GO:0016020;GO:0016491;GO:0016709;GO:0031314;GO:0046872;GO:0055114","K06134-ko00130 Ubiquinone and other terpenoid-quinone biosynthesis","KOG4061-DMQ mono-oxygenase/Ubiquinone biosynthesis protein COQ7/CLK-1/CAT5[R]"]
["PVALB",4.244357,10.522442,1.309851644,{"v":6.81e-43,"d":"6.81E-43"},{"v":2.84e-42,"d":"2.84E-42"},"up","PVALB","parvalbumin","GO:0005509;GO:0005737;GO:0030424;GO:0046872","-","KOG0027-Calmodulin and related proteins (EF-Hand superfamily)[T]"]
["AGBL5",5.476173,13.564141,1.308557757,{"v":1.72e-49,"d":"1.72E-49"},{"v":7.72e-49,"d":"7.72E-49"},"up","AGBL5","-","-","-","KOG3641-Zinc carboxypeptidase[E]"]
["COX20",11.618389,28.750473,1.307175652,{"v":1.75e-35,"d":"1.75E-35"},{"v":6.61e-35,"d":"6.61E-35"},"up","COX20","COX20, cytochrome c oxidase assembly factor","GO:0005739;GO:0005743;GO:0009060;GO:0016020;GO:0016021;GO:0033617","-","-"]
["MSH4",7.925642,19.601852,1.30639026,{"v":7.38e-190,"d":"7.38E-190"},{"v":7.76e-189,"d":"7.76E-189"},"up","MSH4","-","GO:0000793;GO:0000794;GO:0000795;GO:0001541;GO:0003684;GO:0005524;GO:0005634;GO:0005713;GO:0006298;GO:0007129;GO:0007283;GO:0007292;GO:0008094;GO:0030983;GO:0032300;GO:0051026;GO:0051321","-","KOG0220-Mismatch repair ATPase MSH4 (MutS family)[L]"]
["LAMA2",16.008514,39.566277,1.305431926,0,0,"up","LAMA2","-","GO:0005102;GO:0005604;GO:0005623;GO:0007155;GO:0007411;GO:0030155;GO:0030334;GO:0031594;GO:0032224;GO:0042383;GO:0043083;GO:0045995","K05637-ko04151 PI3K-Akt signaling pathway;ko04512 ECM-receptor interaction;ko04510 Focal adhesion;ko05200 Pathways in cancer;ko05222 Small cell lung cancer;ko05146 Amoebiasis;ko05145 Toxoplasmosis","-"]
["EEPD1",21.841442,53.960495,1.304835475,{"v":1.87e-169,"d":"1.87E-169"},{"v":1.82e-168,"d":"1.82E-168"},"up","EEPD1","-","GO:0003677;GO:0006281","-","-"]
["PGAM1",208.910446,514.807739,1.301149109,0,0,"up","PGAM1","phosphoglycerate mutase 1","GO:0003824;GO:0004082;GO:0004619;GO:0005623;GO:0006096;GO:0008152;GO:0016853;GO:0016868;GO:0043209;GO:0003824;GO:0004082;GO:0004619;GO:0005623;GO:0005829;GO:0006094;GO:0006096;GO:0008152;GO:0016787;GO:0016853;GO:0016868;GO:0043209;GO:0043456;GO:0046538","K01834-ko01200 Carbon metabolism;ko01230 Biosynthesis of amino acids;ko00010 Glycolysis / Gluconeogenesis;ko00680 Methane metabolism;ko00260 Glycine, serine and threonine metabolism;ko04922 Glucagon signaling pathway;ko05230 Central carbon metabolism in cancer","KOG0235-Phosphoglycerate mutase[G]"]
["SYNJ2",8.438838,20.791042,1.300845801,{"v":2.51e-139,"d":"2.51E-139"},{"v":2.11e-138,"d":"2.11E-138"},"up","SYNJ2","-","GO:0003676;GO:0003723;GO:0016787;GO:0034595;GO:0042578;GO:0046856","K20279-ko00562 Inositol phosphate metabolism;ko04070 Phosphatidylinositol signaling system","KOG0566-Inositol-1,4,5-triphosphate 5-phosphatase (synaptojanin), INP51/INP52/INP53 family[U]"]
["ACE",16.246962,40.004791,1.300002813,{"v":1.36e-256,"d":"1.36E-256"},{"v":1.83e-255,"d":"1.83E-255"},"up","ACE","angiotensin I converting enzyme","GO:0004180;GO:0006508;GO:0008233;GO:0008237;GO:0008239;GO:0008241;GO:0008270;GO:0008283;GO:0016020;GO:0016021;GO:0016787;GO:0046872;GO:0060319;GO:0001822;GO:0003081;GO:0003779;GO:0004175;GO:0004180;GO:0005615;GO:0005764;GO:0005768;GO:0005886;GO:0006508;GO:0008144;GO:0008233;GO:0008237;GO:0008238;GO:0008239;GO:0008240;GO:0008241;GO:0008270;GO:0008283;GO:0009897;GO:0016020;GO:0016021;GO:0016787;GO:0031404;GO:0031434;GO:0031711;GO:0042447;GO:0043171;GO:0046872;GO:0050435;GO:0050482;GO:0051019;GO:0060177;GO:0060319;GO:0070062;GO:0070573","-","KOG3690-Angiotensin I-converting enzymes - M2 family peptidases[E]"]
["BF2",196.386124,483.432892,1.299622638,0,0,"up","BF2","Major histocompatibility complex class I antigen BF2","GO:0009986;GO:0016020;GO:0016021;GO:0042605","K06751-ko04514 Cell adhesion molecules (CAMs);ko04144 Endocytosis;ko04145 Phagosome;ko04650 Natural killer cell mediated cytotoxicity;ko04612 Antigen processing and presentation;ko05203 Viral carcinogenesis;ko05320 Autoimmune thyroid disease;ko05330 Allograft rejection;ko05332 Graft-versus-host disease;ko05416 Viral myocarditis;ko04940 Type I diabetes mellitus;ko05166 HTLV-I infection;ko05168 Herpes simplex infection;ko05169 Epstein-Barr virus infection","-"]
["ARID5A",8.328405,20.500105,1.299519167,{"v":2.27e-140,"d":"2.27E-140"},{"v":1.92e-139,"d":"1.92E-139"},"up","ARID5A","-","GO:0000122;GO:0003677;GO:0003714;GO:0005634;GO:0005654;GO:0005730;GO:0008134;GO:0030331;GO:0043565;GO:0046965;GO:0046966;GO:0050681;GO:0071391","-","KOG2744-DNA-binding proteins Bright/BRCAA1/RBP1 and related proteins containing BRIGHT domain[K]"]
["SNRKL",8.694499,21.34709,1.295864614,{"v":6.68e-70,"d":"6.68E-70"},{"v":3.61e-69,"d":"3.61E-69"},"up","SNRKL","-","GO:0004672;GO:0004674;GO:0005524;GO:0005634;GO:0005737;GO:0006468;GO:0035556","-","-"]
["NDUFB6",154.17746,378.132751,1.294300944,{"v":3.43e-291,"d":"3.43E-291"},{"v":5.09e-290,"d":"5.09E-290"},"up","NDUFB6","NADH:ubiquinone oxidoreductase subunit B6","GO:0005654;GO:0005739;GO:0005747;GO:0031966;GO:0032981;GO:0042775","K03962-ko00190 Oxidative phosphorylation;ko05010 Alzheimer's disease;ko05012 Parkinson's disease;ko05016 Huntington's disease;ko04932 Non-alcoholic fatty liver disease (NAFLD)","KOG4633-NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit[C]"]
["DMTN",9.043685,22.159178,1.292921718,{"v":6.77e-41,"d":"6.77E-41"},{"v":2.77e-40,"d":"2.77E-40"},"up","DMTN","-","GO:0003779;GO:0005102;GO:0005829;GO:0005884;GO:0005886;GO:0008360;GO:0010591;GO:0014731;GO:0030507;GO:0031095;GO:0031410;GO:0032956;GO:0051489;GO:0065003;GO:0071320","-","KOG1044-Actin-binding LIM Zn-finger protein Limatin involved in axon guidance[TZ]"]
["LOC107053811",3.388478,8.298505,1.292214049,{"v":9.81e-51,"d":"9.81E-51"},{"v":4.45e-50,"d":"4.45E-50"},"up","LOC107053811","-","-","-","-"]
["HIST1H2B8",10.504303,25.717552,1.291772885,{"v":1.95e-15,"d":"1.95E-15"},{"v":5.07e-15,"d":"5.07E-15"},"up","HIST1H2B8","histone cluster 1, H2B-VIII","-","-","KOG1744-Histone H2B[B]"]
["TCHP",6.625539,16.214081,1.291137525,{"v":1.19e-68,"d":"1.19E-68"},{"v":6.36e-68,"d":"6.36E-68"},"up","TCHP","-","GO:0005737;GO:0005739;GO:0005813;GO:0005829;GO:0005886;GO:0006915;GO:0030057;GO:0030308;GO:0045095;GO:0045179;GO:0097539;GO:1902018","-","-"]
["MBLAC1",7.7806,19.024841,1.289931079,{"v":2.2e-34,"d":"2.20E-34"},{"v":8.19e-34,"d":"8.19E-34"},"up","MBLAC1","-","-","-","KOG4736-Uncharacterized conserved protein[S]"]
["LOC107051263",6.453459,15.750689,1.287270394,{"v":2.69e-44,"d":"2.69E-44"},{"v":1.14e-43,"d":"1.14E-43"},"up","LOC107051263","-","-","-","-"]
["MISP",2.396028,5.843981,1.28630672,{"v":1.63e-24,"d":"1.63E-24"},{"v":5.15e-24,"d":"5.15E-24"},"up","MISP","-","-","-","-"]
["TRAK1",16.744869,40.787899,1.284422106,0,0,"up","TRAK1","-","GO:0005737;GO:0005739;GO:0005769;GO:0008333;GO:0050811;GO:0098957;GO:1904115","-","KOG4360-Uncharacterized coiled coil protein[S]"]
["SNX10",5.307627,12.928371,1.284401612,{"v":2.82e-55,"d":"2.82E-55"},{"v":1.34e-54,"d":"1.34E-54"},"up","SNX10","sorting nexin 10","GO:0001696;GO:0005545;GO:0005634;GO:0005768;GO:0005783;GO:0005813;GO:0006897;GO:0007032;GO:0016050;GO:0019898;GO:0030141;GO:0030282;GO:0030316;GO:0031313;GO:0035091;GO:0045453;GO:0051117;GO:0055074;GO:0060271;GO:0061512;GO:0071539;GO:0090651;GO:0097178;GO:1990830","-","KOG2527-Sorting nexin SNX11[U]"]
["YBX3",590.342285,1437.437866,1.283876008,0,0,"up","YBX3","Y-box binding protein 3","GO:0000122;GO:0000977;GO:0001227;GO:0003676;GO:0003677;GO:0003697;GO:0003730;GO:0005634;GO:0005737;GO:0005829;GO:0006355;GO:0007283;GO:0008584;GO:0009566;GO:0043066;GO:0046622;GO:0048642;GO:0060546;GO:0071356;GO:0071474;GO:1902219;GO:1905538","K06099-ko04530 Tight junction","KOG3070-Predicted RNA-binding protein containing PIN domain and invovled in translation or RNA processing[J]"]
["ACOT9",20.049231,48.800545,1.283350357,{"v":1.53e-237,"d":"1.53E-237"},{"v":1.93e-236,"d":"1.93E-236"},"up","ACOT9","acyl-CoA thioesterase 9","-","-","KOG2763-Acyl-CoA thioesterase[I]"]
["DNAAF5",6.143856,14.952859,1.283205048,{"v":4.87e-67,"d":"4.87E-67"},{"v":2.56e-66,"d":"2.56E-66"},"up","DNAAF5","-","-","-","-"]
["EPSTI1",2.143259,5.21421,1.282642486,{"v":1.86e-13,"d":"1.86E-13"},{"v":4.58e-13,"d":"4.58E-13"},"up","EPSTI1","-","-","-","-"]
["TGFBI",51.186584,124.495193,1.282252404,0,0,"up","TGFBI","transforming growth factor beta induced","GO:0001525;GO:0005178;GO:0005518;GO:0005615;GO:0005802;GO:0007155;GO:0008283;GO:0030198;GO:0031012;GO:0050840","-","KOG1437-Fasciclin and related adhesion glycoproteins[MW]"]
["HIST1H4D",16.203623,39.400482,1.281896855,{"v":6.09e-32,"d":"6.09E-32"},{"v":2.19e-31,"d":"2.19E-31"},"up","HIST1H4D","-","-","-","-"]
["E2F5",17.446207,42.329689,1.278756477,{"v":3.02e-127,"d":"3.02E-127"},{"v":2.39e-126,"d":"2.39E-126"},"up","E2F5","E2F transcription factor 5","GO:0001650;GO:0003677;GO:0003700;GO:0005634;GO:0005667;GO:0005730;GO:0005737;GO:0006351;GO:0006355;GO:0008134;GO:0009887;GO:0046983;GO:0051726","K04682-ko04350 TGF-beta signaling pathway;ko04110 Cell cycle","KOG2577-Transcription factor E2F/dimerization partner (TDP)[K]"]
["P2RX6",3.677869,8.914294,1.277250449,{"v":1.31e-23,"d":"1.31E-23"},{"v":4.07e-23,"d":"4.07E-23"},"up","P2RX6","-","GO:0001614;GO:0004931;GO:0005216;GO:0005524;GO:0005639;GO:0005737;GO:0005887;GO:0006811;GO:0016020;GO:0016021;GO:0030054;GO:0033198;GO:0035590;GO:0042802;GO:0051260;GO:0060079;GO:0098655;GO:0098794","K05221-ko04020 Calcium signaling pathway;ko04080 Neuroactive ligand-receptor interaction","-"]
["AGTR1",23.373158,56.649471,1.277209811,{"v":4.85e-151,"d":"4.85E-151"},{"v":4.32e-150,"d":"4.32E-150"},"up","AGTR1","angiotensin II receptor type 1","GO:0004930;GO:0004945;GO:0005886;GO:0007165;GO:0007186;GO:0016020;GO:0016021;GO:0019229;GO:0038166","K04166-ko04020 Calcium signaling pathway;ko04072 Phospholipase D signaling pathway;ko04022 cGMP - PKG signaling pathway;ko04080 Neuroactive ligand-receptor interaction;ko04924 Renin secretion;ko04614 Renin-angiotensin system;ko04925 Aldosterone synthesis and secretion;ko04261 Adrenergic signaling in cardiomyocytes;ko04270 Vascular smooth muscle contraction;ko05200 Pathways in cancer;ko04933 AGE-RAGE signaling pathway in diabetic complications","KOG4219-G protein-coupled receptor[T]"]
["IDH2",230.294495,557.886658,1.276492124,0,0,"up","IDH2","isocitrate dehydrogenase (NADP( )) 2, mitochondrial","GO:0000287;GO:0004448;GO:0004450;GO:0005739;GO:0005777;GO:0005829;GO:0006099;GO:0006102;GO:0016491;GO:0016616;GO:0046872;GO:0051287;GO:0055114","K00031-ko01200 Carbon metabolism;ko01210 2-Oxocarboxylic acid metabolism;ko01230 Biosynthesis of amino acids;ko00020 Citrate cycle (TCA cycle);ko00720 Carbon fixation pathways in prokaryotes;ko00480 Glutathione metabolism;ko04146 Peroxisome","KOG1526-NADP-dependent isocitrate dehydrogenase[C]"]
["CCDC142",3.246954,7.865271,1.276409529,{"v":2.18e-32,"d":"2.18E-32"},{"v":7.93e-32,"d":"7.93E-32"},"up","CCDC142","-","-","-","-"]
["SPTBN2",3.601053,8.71608,1.275260605,{"v":3.06e-90,"d":"3.06E-90"},{"v":1.92e-89,"d":"1.92E-89"},"up","SPTBN2","-","-","-","-"]
["EZR",149.607666,361.719055,1.273685498,0,0,"up","EZR","ezrin","GO:0000122;GO:0001650;GO:0001726;GO:0001772;GO:0001931;GO:0001951;GO:0003376;GO:0003779;GO:0005622;GO:0005737;GO:0005768;GO:0005829;GO:0005856;GO:0005884;GO:0005886;GO:0005902;GO:0005903;GO:0005925;GO:0007159;GO:0008017;GO:0008022;GO:0008092;GO:0008360;GO:0010628;GO:0010737;GO:0015629;GO:0016324;GO:0019898;GO:0019904;GO:0022614;GO:0030033;GO:0030175;GO:0030953;GO:0031532;GO:0031623;GO:0032532;GO:0032991;GO:0034236;GO:0034237;GO:0034629;GO:0035088;GO:0036064;GO:0040018;GO:0042802;GO:0042995;GO:0043209;GO:0043622;GO:0044548;GO:0044853;GO:0045177;GO:0046847;GO:0048015;GO:0048471;GO:0050714;GO:0050839;GO:0050860;GO:0051015;GO:0051017;GO:0051018;GO:0051117;GO:0051660;GO:0061028;GO:0070373;GO:0071320;GO:0071437;GO:0071944;GO:0072659;GO:0072697;GO:0097718;GO:0098592;GO:1900041;GO:1902115;GO:1902896;GO:1902966;GO:1903078;GO:1903364;GO:1903753;GO:2000643","K08007-ko04810 Regulation of actin cytoskeleton;ko04670 Leukocyte transendothelial migration;ko04971 Gastric acid secretion;ko05206 MicroRNAs in cancer;ko05205 Proteoglycans in cancer;ko05130 Pathogenic Escherichia coli infection","KOG3529-Radixin, moesin and related proteins of the ERM family[R]"]
["HK2",24.74217,59.80547,1.273305407,{"v":2.39e-225,"d":"2.39E-225"},{"v":2.89e-224,"d":"2.89E-224"},"up","HK2","hexokinase 2","GO:0000166;GO:0001678;GO:0004340;GO:0004396;GO:0005524;GO:0005536;GO:0005623;GO:0005741;GO:0005829;GO:0005975;GO:0006006;GO:0006096;GO:0008637;GO:0016301;GO:0016310;GO:0016740;GO:0016773;GO:0035795;GO:0045766;GO:0046324;GO:0046835;GO:0051156;GO:0072655;GO:0072656;GO:1904659;GO:1904925;GO:1990830;GO:2000378","K00844-ko01200 Carbon metabolism;ko00010 Glycolysis / Gluconeogenesis;ko00051 Fructose and mannose metabolism;ko00052 Galactose metabolism;ko00500 Starch and sucrose metabolism;ko00520 Amino sugar and nucleotide sugar metabolism;ko00521 Streptomycin biosynthesis;ko00524 Neomycin, kanamycin and gentamicin biosynthesis;ko04066 HIF-1 signaling pathway;ko04910 Insulin signaling pathway;ko04973 Carbohydrate digestion and absorption;ko05230 Central carbon metabolism in cancer;ko04930 Type II diabetes mellitus","KOG1369-Hexokinase[G]"]
["MDH1",171.755981,414.422821,1.270743112,0,0,"up","MDH1","malate dehydrogenase 1","GO:0003824;GO:0005975;GO:0006099;GO:0006108;GO:0016491;GO:0016615;GO:0016616;GO:0019752;GO:0030060;GO:0043209;GO:0055114;GO:0003824;GO:0005615;GO:0005737;GO:0005739;GO:0005829;GO:0005975;GO:0006099;GO:0006107;GO:0006108;GO:0006734;GO:0016491;GO:0016615;GO:0016616;GO:0019752;GO:0030060;GO:0055114","K00025-ko01200 Carbon metabolism;ko00020 Citrate cycle (TCA cycle);ko00620 Pyruvate metabolism;ko00630 Glyoxylate and dicarboxylate metabolism;ko00710 Carbon fixation in photosynthetic organisms;ko00270 Cysteine and methionine metabolism;ko04964 Proximal tubule bicarbonate reclamation","KOG1496-Malate dehydrogenase[C]"]
["NRF1",3.137788,7.567877,1.270140759,0.002531382,0.003770307,"up","NRF1","nuclear respiratory factor 1","GO:0000122;GO:0000976;GO:0000978;GO:0003677;GO:0003700;GO:0005634;GO:0005737;GO:0005783;GO:0005789;GO:0006351;GO:0006355;GO:0006357;GO:0006366;GO:0006629;GO:0008202;GO:0008203;GO:0008289;GO:0015485;GO:0016020;GO:0016021;GO:0030176;GO:0034599;GO:0036003;GO:0042632;GO:0045454;GO:0045893;GO:0055088;GO:0071397;GO:0097201;GO:1901329","K11831-ko05016 Huntington's disease","-"]
["LOC107049129",2.352648,5.672823,1.269781368,{"v":1.47e-30,"d":"1.47E-30"},{"v":5.2e-30,"d":"5.20E-30"},"up","LOC107049129","-","-","-","-"]
["MKNK1",4.456094,10.742496,1.269477669,{"v":1.77e-46,"d":"1.77E-46"},{"v":7.72e-46,"d":"7.72E-46"},"up","MKNK1","-","GO:0000166;GO:0004672;GO:0004674;GO:0004683;GO:0005516;GO:0005524;GO:0005634;GO:0005737;GO:0006468;GO:0009931;GO:0018105;GO:0035556;GO:0046777","K04372-ko04010 MAPK signaling pathway;ko04066 HIF-1 signaling pathway;ko04910 Insulin signaling pathway","KOG0607-MAP kinase-interacting kinase and related serine/threonine protein kinases[T]"]
["NRXN1",43.754814,105.480057,1.269456597,{"v":2.86e-298,"d":"2.86E-298"},{"v":4.32e-297,"d":"4.32E-297"},"up","NRXN1","neurexin 1","GO:0001525;GO:0005246;GO:0005730;GO:0005783;GO:0005886;GO:0007155;GO:0007268;GO:0007269;GO:0007416;GO:0007612;GO:0009986;GO:0016020;GO:0016021;GO:0030534;GO:0031965;GO:0031982;GO:0032991;GO:0033130;GO:0035176;GO:0042297;GO:0042734;GO:0043025;GO:0046872;GO:0050839;GO:0050885;GO:0051965;GO:0051968;GO:0060134;GO:0061178;GO:0071625;GO:0090129;GO:0097104;GO:0097109;GO:0097116;GO:0097118;GO:0097119;GO:0098685;GO:0098693;GO:0098978;GO:0098982;GO:0099056;GO:0099059;GO:0099150;GO:0099560;GO:1905606;GO:2000463;GO:2000821","K07377-ko04514 Cell adhesion molecules (CAMs)","KOG3514-Neurexin III-alpha[T]"]
["CISD3",16.113226,38.808868,1.26814099,{"v":1.03e-31,"d":"1.03E-31"},{"v":3.69e-31,"d":"3.69E-31"},"up","CISD3","-","-","-","-"]
["GCGR",2.183061,5.257048,1.267900464,{"v":5.47e-15,"d":"5.47E-15"},{"v":1.41e-14,"d":"1.41E-14"},"up","GCGR","glucagon receptor","GO:0004888;GO:0004930;GO:0004967;GO:0005622;GO:0005887;GO:0007165;GO:0007166;GO:0007186;GO:0007188;GO:0007189;GO:0016020;GO:0016021;GO:0042593;GO:0042594;GO:0070873;GO:0071377","K04583-ko04080 Neuroactive ligand-receptor interaction;ko04922 Glucagon signaling pathway","KOG4564-Adenylate cyclase-coupled calcitonin receptor[T]"]
["HSPB1",925.615295,2228.727295,1.267735492,0,0,"up","HSPB1","heat shock protein family B (small) member 1","GO:0001932;GO:0005080;GO:0005622;GO:0005634;GO:0005737;GO:0005739;GO:0005819;GO:0005856;GO:0005886;GO:0006469;GO:0008426;GO:0009408;GO:0009615;GO:0019901;GO:0030018;GO:0030837;GO:0032731;GO:0035556;GO:0035924;GO:0038033;GO:0042535;GO:0042802;GO:0042803;GO:0043122;GO:0043292;GO:0043536;GO:0044183;GO:0045766;GO:0051016;GO:0051693;GO:0061077;GO:0071901;GO:0099641;GO:1902176;GO:1904115;GO:2001028;GO:2001234","K04455-ko04010 MAPK signaling pathway;ko04370 VEGF signaling pathway;ko05169 Epstein-Barr virus infection;ko05146 Amoebiasis","KOG3591-Alpha crystallins[O]"]
["LOC770248",4.440102,10.687731,1.267290878,0.001281801,0.001965351,"up","LOC770248","-","-","-","-"]
["RSPO2",4.428462,10.62832,1.263035926,{"v":4.66e-12,"d":"4.66E-12"},{"v":1.1e-11,"d":"1.10E-11"},"up","RSPO2","R-spondin 2","GO:0001649;GO:0005102;GO:0005576;GO:0008201;GO:0009986;GO:0030282;GO:0035115;GO:0035116;GO:0042489;GO:0060437;GO:0060441;GO:0060535;GO:0071542;GO:0090263","-","-"]
["ZNF226L",2.248714,5.392055,1.261735027,{"v":2.59e-19,"d":"2.59E-19"},{"v":7.42e-19,"d":"7.42E-19"},"up","ZNF226L","-","GO:0003676;GO:0005622;GO:0006355;GO:0046872","-","KOG2462-C2H2-type Zn-finger protein[K]"]
["FILIP1",28.55641,68.363487,1.259411365,0,0,"up","FILIP1","-","GO:0005730;GO:0005886;GO:0015629","-","KOG1103-Predicted coiled-coil protein[S]"]
["OLFML1",8.945921,21.381216,1.257041982,{"v":2.89e-149,"d":"2.89E-149"},{"v":2.56e-148,"d":"2.56E-148"},"up","OLFML1","-","-","-","KOG3545-Olfactomedin and related extracellular matrix glycoproteins[W]"]
["C5H11ORF96",80.968491,193.486053,1.256797081,{"v":3.75e-257,"d":"3.75E-257"},{"v":5.04e-256,"d":"5.04E-256"},"up","C5H11ORF96","chromosome 5 open reading frame, human C11orf96","-","-","-"]
["LOC107052929",2.253666,5.375902,1.254233119,{"v":1.89e-12,"d":"1.89E-12"},{"v":4.53e-12,"d":"4.53E-12"},"up","LOC107052929","-","-","-","-"]
["PLA2G6",8.10955,19.336843,1.253658508,{"v":4.28e-91,"d":"4.28E-91"},{"v":2.7e-90,"d":"2.70E-90"},"up","PLA2G6","phospholipase A2 group VI","GO:0005615;GO:0005815;GO:0005829;GO:0006629;GO:0008152;GO:0016042;GO:0016787;GO:0017171;GO:0019731;GO:0032049","K16343-ko00564 Glycerophospholipid metabolism;ko00565 Ether lipid metabolism;ko00590 Arachidonic acid metabolism;ko00591 Linoleic acid metabolism;ko00592 alpha-Linolenic acid metabolism;ko04014 Ras signaling pathway;ko04270 Vascular smooth muscle contraction;ko04750 Inflammatory mediator regulation of TRP channels","KOG0513-Ca2+-independent phospholipase A2[I]"]
["TCTEX1D2",6.620524,15.782577,1.253315477,{"v":2.99e-22,"d":"2.99E-22"},{"v":9.07e-22,"d":"9.07E-22"},"up","TCTEX1D2","-","-","-","-"]
["LARP6",8.411733,20.023764,1.25123823,{"v":1.45e-82,"d":"1.45E-82"},{"v":8.6e-82,"d":"8.60E-82"},"up","LARP6","-","GO:0003723;GO:0005634;GO:0005844;GO:0006396;GO:0006417;GO:0017022;GO:0032967;GO:0035613;GO:0045727;GO:0048027;GO:1902416;GO:1990825;GO:1990904","-","KOG1855-Predicted RNA-binding protein[R]"]
["CH25H",10.751338,25.590303,1.251081016,{"v":3.83e-49,"d":"3.83E-49"},{"v":1.71e-48,"d":"1.71E-48"},"up","CH25H","cholesterol 25-hydroxylase","GO:0001567;GO:0005506;GO:0008203;GO:0008395;GO:0008610;GO:0016020;GO:0016021;GO:0016491;GO:0035754;GO:0055114","K10223-ko00120 Primary bile acid biosynthesis","KOG0873-C-4 sterol methyl oxidase[I]"]
["CD320",14.532214,34.545959,1.249262446,{"v":3.04e-29,"d":"3.04E-29"},{"v":1.05e-28,"d":"1.05E-28"},"up","CD320","CD320 molecule","GO:0005743;GO:0005747;GO:0006120;GO:0008137;GO:0016020;GO:0016021;GO:0042773","-","-"]
["TFB1M",6.587934,15.645413,1.247841736,{"v":1.03e-44,"d":"1.03E-44"},{"v":4.4e-44,"d":"4.40E-44"},"up","TFB1M","-","GO:0000154;GO:0000179;GO:0003723;GO:0005737;GO:0006364;GO:0008168;GO:0008649;GO:0016740;GO:0031167;GO:0032259;GO:0042645","-","KOG0821-Predicted ribosomal RNA adenine dimethylase[A]"]
["DIO2",5.542606,13.154891,1.246962933,{"v":3.29e-108,"d":"3.29E-108"},{"v":2.32e-107,"d":"2.32E-107"},"up","DIO2","iodothyronine deiodinase 2","GO:0004800;GO:0006590;GO:0016020;GO:0016021;GO:0016491;GO:0042404;GO:0042446;GO:0055114;GO:0120162","-","-"]
["CLGN",3.888655,9.228539,1.246831023,{"v":3.23e-36,"d":"3.23E-36"},{"v":1.23e-35,"d":"1.23E-35"},"up","CLGN","-","GO:0005509;GO:0005635;GO:0005783;GO:0006457;GO:0007338;GO:0007339;GO:0016020;GO:0016021;GO:0044183;GO:0051082;GO:0065003","-","KOG0675-Calnexin[O]"]
["ASB2",18.99674,45.049816,1.245769352,{"v":1.06e-271,"d":"1.06E-271"},{"v":1.48e-270,"d":"1.48E-270"},"up","ASB2","-","GO:0000151;GO:0000209;GO:0006511;GO:0016567;GO:0031466;GO:0035556;GO:0035914;GO:0045445;GO:0061630","-","KOG4177-Ankyrin[M]"]
["ETFA",97.337456,230.721024,1.245082499,0,0,"up","ETFA","electron-transfer-flavoprotein, alpha polypeptide","GO:0005739;GO:0009055;GO:0016491;GO:0022900;GO:0033539;GO:0050660","-","KOG3954-Electron transfer flavoprotein, alpha subunit[C]"]
["GPR176",2.860882,6.779855,1.244794425,{"v":4.71e-20,"d":"4.71E-20"},{"v":1.37e-19,"d":"1.37E-19"},"up","GPR176","-","GO:0004930;GO:0005886;GO:0007186;GO:0007193;GO:0016020;GO:0016021;GO:0048512","-","KOG4219-G protein-coupled receptor[T]"]
["CD7",8.072477,19.094606,1.242081821,{"v":6.93e-60,"d":"6.93E-60"},{"v":3.44e-59,"d":"3.44E-59"},"up","CD7","CD7 molecule","-","-","-"]
["APBB2",16.959881,40.092571,1.241208888,{"v":3.49e-168,"d":"3.49E-168"},{"v":3.38e-167,"d":"3.38E-167"},"up","APBB2","-","GO:0001540;GO:0001764;GO:0005634;GO:0005737;GO:0006355;GO:0007050;GO:0007411;GO:0008134;GO:0030198;GO:0030308;GO:0043065;GO:0043066","-","-"]
["IL11RA",12.139431,28.635578,1.238107923,{"v":1.3e-64,"d":"1.30E-64"},{"v":6.7e-64,"d":"6.70E-64"},"up","IL11RA","interleukin 11 receptor subunit alpha","GO:0004896;GO:0016020;GO:0016021;GO:0019221;GO:0032502;GO:0060322","K05056-ko04630 Jak-STAT signaling pathway;ko04060 Cytokine-cytokine receptor interaction;ko04640 Hematopoietic cell lineage","-"]
["VRK3",19.152277,45.173744,1.237968566,{"v":1.65e-84,"d":"1.65E-84"},{"v":9.96e-84,"d":"9.96E-84"},"up","VRK3","-","-","-","-"]
["ACADSB",15.239641,35.918148,1.236884047,{"v":1.51e-220,"d":"1.51E-220"},{"v":1.8e-219,"d":"1.80E-219"},"up","ACADSB","acyl-CoA dehydrogenase, short/branched chain","GO:0003995;GO:0005739;GO:0016491;GO:0016627;GO:0050660;GO:0055114","K09478-ko01212 Fatty acid metabolism;ko00071 Fatty acid degradation;ko00280 Valine, leucine and isoleucine degradation","KOG0139-Short-chain acyl-CoA dehydrogenase[I]"]
["LOC112530277",15.838281,37.303581,1.235898369,{"v":4.07e-06,"d":"4.07E-06"},{"v":7.43e-06,"d":"7.43E-06"},"up","LOC112530277","-","-","-","-"]
["TMEM237",13.484015,31.704441,1.233434803,{"v":3.81e-107,"d":"3.81E-107"},{"v":2.66e-106,"d":"2.66E-106"},"up","TMEM237","transmembrane protein 237","GO:0005929;GO:0016020;GO:0016021;GO:0030030;GO:0030111;GO:0035869;GO:0042995;GO:0060271","-","-"]
["ASL2",24.092201,56.565804,1.231363957,{"v":9.26e-129,"d":"9.26E-129"},{"v":7.4e-128,"d":"7.40E-128"},"up","ASL2","argininosuccinate lyase 2","GO:0003824;GO:0004056;GO:0005212;GO:0005737;GO:0005829;GO:0006525;GO:0006526;GO:0008652;GO:0016829;GO:0042450","K01755-ko01230 Biosynthesis of amino acids;ko00250 Alanine, aspartate and glutamate metabolism;ko00220 Arginine biosynthesis","KOG1316-Argininosuccinate lyase[E]"]
["SETD9",9.560156,22.417362,1.229510452,{"v":7.87e-30,"d":"7.87E-30"},{"v":2.74e-29,"d":"2.74E-29"},"up","SETD9","-","-","-","-"]
["IFT74",9.348206,21.916859,1.229279623,{"v":3.04e-68,"d":"3.04E-68"},{"v":1.62e-67,"d":"1.62E-67"},"up","IFT74","-","GO:0003334;GO:0003682;GO:0005634;GO:0005813;GO:0005929;GO:0007219;GO:0007368;GO:0007507;GO:0008544;GO:0030992;GO:0033630;GO:0035735;GO:0042073;GO:0045944;GO:0048487;GO:0050680;GO:0060271;GO:1905515","-","-"]
["AGTR2",4.226518,9.891183,1.226673486,{"v":2.8e-37,"d":"2.80E-37"},{"v":1.08e-36,"d":"1.08E-36"},"up","AGTR2","-","GO:0001991;GO:0002033;GO:0002035;GO:0004930;GO:0004945;GO:0005622;GO:0006954;GO:0007165;GO:0007166;GO:0007186;GO:0007199;GO:0010459;GO:0016020;GO:0016021;GO:0032516;GO:0035556;GO:0035566;GO:0035640;GO:0038166;GO:0042311;GO:0042981;GO:0045893;GO:0051000;GO:0051387;GO:0072300;GO:0090190;GO:0097746;GO:2001238","K04167-ko04080 Neuroactive ligand-receptor interaction;ko04614 Renin-angiotensin system;ko04261 Adrenergic signaling in cardiomyocytes","KOG4219-G protein-coupled receptor[T]"]
["VIM",309.460632,724.207336,1.226646902,0,0,"up","VIM","vimentin","GO:0003725;GO:0005198;GO:0005200;GO:0005212;GO:0005623;GO:0005634;GO:0005737;GO:0005777;GO:0005829;GO:0005844;GO:0005856;GO:0005882;GO:0005886;GO:0008022;GO:0010628;GO:0010977;GO:0014002;GO:0016363;GO:0019904;GO:0031252;GO:0032967;GO:0042802;GO:0042995;GO:0043005;GO:0043488;GO:0045103;GO:0045109;GO:0045335;GO:0045727;GO:0060020;GO:0060395;GO:0070307;GO:0071222;GO:0071225;GO:0071346;GO:0097110;GO:1990254;GO:1990904","-","KOG0977-Nuclear envelope protein lamin, intermediate filament superfamily[DY]"]
["TNFRSF11B",20.324642,47.427765,1.222501943,{"v":3.62e-141,"d":"3.62E-141"},{"v":3.08e-140,"d":"3.08E-140"},"up","TNFRSF11B","TNF receptor superfamily member 11b","GO:0005615;GO:0006915;GO:0007165;GO:0030198;GO:0031012;GO:0042489","K05148-ko04060 Cytokine-cytokine receptor interaction;ko04380 Osteoclast differentiation","-"]
["MRPL2",122.776093,286.156372,1.220774067,0,0,"up","MRPL2","-","GO:0002181;GO:0003723;GO:0003735;GO:0005622;GO:0005739;GO:0005762;GO:0005840;GO:0006412;GO:0015934;GO:0016740;GO:0032543","K02886-ko03010 Ribosome","KOG0438-Mitochondrial/chloroplast ribosomal protein L2[J]"]
["ABHD6",8.052372,18.763559,1.220447771,{"v":3.09e-56,"d":"3.09E-56"},{"v":1.48e-55,"d":"1.48E-55"},"up","ABHD6","-","GO:0004620;GO:0005739;GO:0009395;GO:0016020;GO:0016021;GO:0030336;GO:0032281;GO:0046464;GO:0046889;GO:0047372;GO:0060292;GO:0098978;GO:0098982;GO:0099055;GO:0120163;GO:2000124","-","KOG1454-Predicted hydrolase/acyltransferase (alpha/beta hydrolase superfamily)[R]"]
["MYL12A",279.73468,651.385254,1.219451938,0,0,"up","MYL12A","myosin, light chain 12A, regulatory, non-sarcomeric","-","K12757-ko04810 Regulation of actin cytoskeleton;ko04510 Focal adhesion;ko04530 Tight junction;ko04611 Platelet activation;ko04670 Leukocyte transendothelial migration","KOG0031-Myosin regulatory light chain, EF-Hand protein superfamily[Z]"]
["SLC2A9",5.8486,13.606615,1.218144975,{"v":2.57e-96,"d":"2.57E-96"},{"v":1.68e-95,"d":"1.68E-95"},"up","SLC2A9","-","GO:0005215;GO:0005355;GO:0005635;GO:0005886;GO:0005887;GO:0015143;GO:0015747;GO:0016020;GO:0016021;GO:0022857;GO:0046415;GO:0055085;GO:1904659","-","KOG0569-Permease of the major facilitator superfamily[G]"]
["PKIB",9.131231,21.243471,1.218138238,{"v":4.22e-29,"d":"4.22E-29"},{"v":1.45e-28,"d":"1.45E-28"},"up","PKIB","protein kinase (cAMP-dependent, catalytic) inhibitor beta","GO:0004862;GO:0005634;GO:0005737;GO:0006469;GO:0032212;GO:0051973;GO:1904355;GO:2000480","-","-"]
["GSTAL1",23.614979,54.919609,1.217619102,{"v":2.31e-61,"d":"2.31E-61"},{"v":1.16e-60,"d":"1.16E-60"},"up","GSTAL1","-","GO:0004364;GO:0008152","-","-"]
["MGAT4A",8.404798,19.517887,1.215511824,{"v":2.62e-66,"d":"2.62E-66"},{"v":1.37e-65,"d":"1.37E-65"},"up","MGAT4A","mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A","GO:0000139;GO:0005794;GO:0006486;GO:0006487;GO:0008375;GO:0008454;GO:0016020;GO:0016021;GO:0016740;GO:0016757;GO:0046872","K00738-ko00510 N-Glycan biosynthesis;ko00513 Various types of N-glycan biosynthesis","-"]
["LOC107052546",10.575535,24.524263,1.213479133,{"v":4.68e-24,"d":"4.68E-24"},{"v":1.47e-23,"d":"1.47E-23"},"up","LOC107052546","-","-","-","-"]
["PRKAG2",22.750847,52.753239,1.21333942,{"v":3.13e-137,"d":"3.13E-137"},{"v":2.61e-136,"d":"2.61E-136"},"up","PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","GO:0004862;GO:0005524;GO:0005977;GO:0006110;GO:0006469;GO:0008603;GO:0008607;GO:0010800;GO:0016301;GO:0016310;GO:0019217;GO:0019901;GO:0030295;GO:0031588;GO:0032147;GO:0032559;GO:0035556;GO:0043531;GO:0045860;GO:0071900;GO:0071901;GO:0016301;GO:0016310;GO:0032559;GO:0071900","K07200-ko04068 FoxO signaling pathway;ko04152 AMPK signaling pathway;ko04910 Insulin signaling pathway;ko04922 Glucagon signaling pathway;ko04920 Adipocytokine signaling pathway;ko04921 Oxytocin signaling pathway;ko04211 Longevity regulating pathway - mammal;ko04213 Longevity regulating pathway - multiple species;ko04710 Circadian rhythm;ko05410 Hypertrophic cardiomyopathy (HCM);ko04932 Non-alcoholic fatty liver disease (NAFLD);ko04931 Insulin resistance","KOG1764-5'-AMP-activated protein kinase, gamma subunit[C]"]
["RNF219",7.14412,16.557089,1.212620828,{"v":2.65e-73,"d":"2.65E-73"},{"v":1.47e-72,"d":"1.47E-72"},"up","RNF219","-","-","-","KOG0320-Predicted E3 ubiquitin ligase[O]"]
["GLIPR2",7.21234,16.713776,1.212498392,{"v":9.58e-52,"d":"9.58E-52"},{"v":4.38e-51,"d":"4.38E-51"},"up","GLIPR2","-","GO:0005576","-","KOG3017-Defense-related protein containing SCP domain[S]"]
["MRPS36",36.659405,84.912064,1.211786171,{"v":5.67e-57,"d":"5.67E-57"},{"v":2.74e-56,"d":"2.74E-56"},"up","MRPS36","-","GO:0005739;GO:0005763;GO:0009353","-","-"]
["TGFB3",43.428684,100.53334,1.210953882,{"v":4.49e-280,"d":"4.49E-280"},{"v":6.44e-279,"d":"6.44E-279"},"up","TGFB3","transforming growth factor beta 3","GO:0001666;GO:0001775;GO:0003198;GO:0005114;GO:0005125;GO:0005160;GO:0005576;GO:0005615;GO:0007162;GO:0007179;GO:0007399;GO:0007435;GO:0008083;GO:0008284;GO:0008285;GO:0010469;GO:0010718;GO:0010862;GO:0010936;GO:0030335;GO:0030501;GO:0030509;GO:0031012;GO:0032570;GO:0032967;GO:0034713;GO:0034714;GO:0042127;GO:0042802;GO:0042981;GO:0043231;GO:0043408;GO:0043932;GO:0045216;GO:0045893;GO:0048468;GO:0048536;GO:0048566;GO:0050431;GO:0050714;GO:0051496;GO:0051781;GO:0060317;GO:0060325;GO:0060395;GO:0062023;GO:0070483;GO:0090131;GO:1904706;GO:1905075","K13377-ko04010 MAPK signaling pathway;ko04350 TGF-beta signaling pathway;ko04390 Hippo signaling pathway;ko04068 FoxO signaling pathway;ko04060 Cytokine-cytokine receptor interaction;ko04144 Endocytosis;ko04110 Cell cycle;ko05200 Pathways in cancer;ko05210 Colorectal cancer;ko05212 Pancreatic cancer;ko05220 Chronic myeloid leukemia;ko05211 Renal cell carcinoma;ko05323 Rheumatoid arthritis;ko05321 Inflammatiory bowel disease (IBD);ko05410 Hypertrophic cardiomyopathy (HCM);ko05414 Dilated cardiomyopathy (DCM);ko04933 AGE-RAGE signaling pathway in diabetic complications;ko05152 Tuberculosis;ko05166 HTLV-I infection;ko05161 Hepatitis B;ko05146 Amoebiasis;ko05144 Malaria;ko05145 Toxoplasmosis;ko05140 Leishmaniasis;ko05142 Chagas disease (American trypanosomiasis)","KOG3900-Transforming growth factor beta, bone morphogenetic protein and related proteins[T]"]
["CEP290",2.609492,6.03966,1.210698357,{"v":2.33e-61,"d":"2.33E-61"},{"v":1.17e-60,"d":"1.17E-60"},"up","CEP290","-","GO:0000930;GO:0005634;GO:0005737;GO:0005813;GO:0005814;GO:0005829;GO:0032991;GO:0034451;GO:0035869;GO:0042802;GO:0045893;GO:0060271;GO:0070201;GO:0090316","-","-"]
["SHE",19.925125,46.11161,1.210541264,{"v":2.59e-110,"d":"2.59E-110"},{"v":1.86e-109,"d":"1.86E-109"},"up","SHE","-","-","-","KOG4278-Protein tyrosine kinase[T]"]
["UBE2D1",45.912113,106.216606,1.210062601,{"v":6.25e-175,"d":"6.25E-175"},{"v":6.22e-174,"d":"6.22E-174"},"up","UBE2D1","ubiquitin conjugating enzyme E2 D1","GO:0000151;GO:0000166;GO:0000209;GO:0004842;GO:0005524;GO:0005737;GO:0006511;GO:0016740;GO:0031398;GO:0032991;GO:0061631;GO:0070936;GO:1902916","K06689-ko04141 Protein processing in endoplasmic reticulum;ko04120 Ubiquitin mediated proteolysis;ko04013 MAPK signaling pathway - fly;ko04624 Toll and Imd signaling pathway","KOG0417-Ubiquitin-protein ligase[O]"]
["NDUFS1",64.124786,148.346176,1.210013727,0,0,"up","NDUFS1","NADH:ubiquinone oxidoreductase core subunit S1","GO:0005739;GO:0005747;GO:0005758;GO:0008137;GO:0008637;GO:0009055;GO:0016020;GO:0016491;GO:0016651;GO:0042773;GO:0043209;GO:0045272;GO:0045333;GO:0046034;GO:0051536;GO:0051881;GO:0055114;GO:0072593","K03934-ko00190 Oxidative phosphorylation;ko05010 Alzheimer's disease;ko05012 Parkinson's disease;ko05016 Huntington's disease;ko04932 Non-alcoholic fatty liver disease (NAFLD)","KOG2282-NADH-ubiquinone oxidoreductase, NDUFS1/75 kDa subunit[C]"]
["LOC112532392",2.27473,5.260328,1.209457445,{"v":5.2e-09,"d":"5.20E-09"},{"v":1.09e-08,"d":"1.09E-08"},"up","LOC112532392","-","-","-","-"]
["CREM",29.637814,68.434738,1.207289792,{"v":2.85e-141,"d":"2.85E-141"},{"v":2.43e-140,"d":"2.43E-140"},"up","CREM","cAMP responsive element modulator","GO:0000122;GO:0000977;GO:0003677;GO:0003700;GO:0005634;GO:0005667;GO:0006355;GO:0006687;GO:0007283;GO:0045944","K09052-ko04261 Adrenergic signaling in cardiomyocytes;ko05166 HTLV-I infection","KOG3584-cAMP response element binding protein and related transcription factors[K]"]
["LDLRAD4",10.305826,23.789991,1.206894586,{"v":4.24e-231,"d":"4.24E-231"},{"v":5.24e-230,"d":"5.24E-230"},"up","LDLRAD4","low density lipoprotein receptor class A domain containing 4","GO:0005654;GO:0010719;GO:0010991;GO:0016020;GO:0016021;GO:0030336;GO:0030512;GO:0043231;GO:0060394;GO:0070412","-","-"]
["LOC112532948",4.588245,10.58956,1.206628312,0.022464954,0.029911446,"up","LOC112532948","-","-","-","-"]
["MIA2",10.362015,23.89698,1.205523731,{"v":4.17e-121,"d":"4.17E-121"},{"v":3.19e-120,"d":"3.19E-120"},"up","MIA2","-","GO:0016020;GO:0016021","-","-"]
["AHI1",5.716549,13.166978,1.203707885,{"v":4.2e-95,"d":"4.20E-95"},{"v":2.73e-94,"d":"2.73E-94"},"up","AHI1","-","GO:0005813;GO:0005911;GO:0005912;GO:0005929;GO:0036064;GO:0042802;GO:0060271","-","KOG0266-WD40 repeat-containing protein[R]"]
["IGF2",11.229802,25.842382,1.202406565,{"v":2.34e-144,"d":"2.34E-144"},{"v":2.03e-143,"d":"2.03E-143"},"up","IGF2","insulin like growth factor 2","GO:0000122;GO:0001649;GO:0001934;GO:0005158;GO:0005159;GO:0005178;GO:0005179;GO:0005576;GO:0005615;GO:0008083;GO:0008284;GO:0009887;GO:0010469;GO:0031017;GO:0031056;GO:0038028;GO:0040018;GO:0042104;GO:0043085;GO:0043410;GO:0043539;GO:0045725;GO:0045840;GO:0045944;GO:0046628;GO:0048018;GO:0050731;GO:0051146;GO:0051147;GO:0051781;GO:0051897;GO:0071902;GO:2000467","K13769-ko05205 Proteoglycans in cancer","-"]
["RAPGEF4",3.377849,7.773171,1.202398417,{"v":1.98e-38,"d":"1.98E-38"},{"v":7.8e-38,"d":"7.80E-38"},"up","RAPGEF4","-","GO:0005085;GO:0005088;GO:0005622;GO:0005829;GO:0007264;GO:0017016;GO:0017156;GO:0017157;GO:0019933;GO:0030073;GO:0030552;GO:0035556;GO:0098686;GO:0098693","K04351-ko04015 Rap1 signaling pathway;ko04072 Phospholipase D signaling pathway;ko04024 cAMP signaling pathway;ko04670 Leukocyte transendothelial migration;ko04911 Insulin secretion;ko04261 Adrenergic signaling in cardiomyocytes","KOG2378-cAMP-regulated guanine nucleotide exchange factor[T]"]
["PGM1",67.96904,156.340134,1.201738528,0,0,"up","PGM1","phosphoglucomutase 1","GO:0000287;GO:0004614;GO:0005829;GO:0005975;GO:0005978;GO:0006006;GO:0015629;GO:0016868;GO:0019388;GO:0046872;GO:0071704","K01835-ko00010 Glycolysis / Gluconeogenesis;ko00030 Pentose phosphate pathway;ko00052 Galactose metabolism;ko00500 Starch and sucrose metabolism;ko00520 Amino sugar and nucleotide sugar metabolism;ko00230 Purine metabolism;ko00521 Streptomycin biosynthesis","KOG0625-Phosphoglucomutase[G]"]
["PTGER2",5.758318,13.241969,1.20139829,{"v":7.92e-20,"d":"7.92E-20"},{"v":2.29e-19,"d":"2.29E-19"},"up","PTGER2","prostaglandin E receptor 2","GO:0004930;GO:0004957;GO:0005622;GO:0007165;GO:0007186;GO:0007189;GO:0016020;GO:0016021;GO:0032496;GO:0032570;GO:0042127;GO:0071380","K04259-ko04024 cAMP signaling pathway;ko04080 Neuroactive ligand-receptor interaction;ko04924 Renin secretion;ko04750 Inflammatory mediator regulation of TRP channels;ko05200 Pathways in cancer","-"]
["EXOC6",12.718024,29.225544,1.200355343,{"v":2.06e-93,"d":"2.06E-93"},{"v":1.33e-92,"d":"1.33E-92"},"up","EXOC6","exocyst complex component 6","GO:0000145;GO:0006887;GO:0006904","-","KOG2176-Exocyst complex, subunit SEC15[U]"]
["FAIM2",6.758533,15.524264,1.199742837,{"v":1.76e-71,"d":"1.76E-71"},{"v":9.59e-71,"d":"9.59E-71"},"up","FAIM2","-","GO:0002931;GO:0005783;GO:0005794;GO:0016020;GO:0016021;GO:0021549;GO:0021680;GO:0021681;GO:0021702;GO:0043523;GO:0043524;GO:0045121;GO:1902042;GO:2001234","-","KOG2322-N-methyl-D-aspartate receptor glutamate-binding subunit[T]"]
["CPEB3",4.173223,9.576257,1.198299856,{"v":3.12e-82,"d":"3.12E-82"},{"v":1.85e-81,"d":"1.85E-81"},"up","CPEB3","-","GO:0000122;GO:0000900;GO:0003676;GO:0003723;GO:0003730;GO:0005634;GO:0005737;GO:0006412;GO:0006417;GO:0008135;GO:0017148;GO:0030014;GO:0043005;GO:0043022;GO:0045182;GO:0045202;GO:0060213;GO:0061158;GO:0071230;GO:1900153;GO:1990124;GO:2000766","K02602-ko04114 Oocyte meiosis;ko04914 Progesterone-mediated oocyte maturation;ko04320 Dorso-ventral axis formation","KOG0129-Predicted RNA-binding protein (RRM superfamily)[J]"]
["ADRB2",7.367373,16.884701,1.196494441,{"v":2e-93,"d":"2.00E-93"},{"v":1.29e-92,"d":"1.29E-92"},"up","ADRB2","-","-","K04142-ko04020 Calcium signaling pathway;ko04024 cAMP signaling pathway;ko04022 cGMP - PKG signaling pathway;ko04080 Neuroactive ligand-receptor interaction;ko04144 Endocytosis;ko04923 Regulation of lipolysis in adipocyte;ko04924 Renin secretion;ko04261 Adrenergic signaling in cardiomyocytes;ko04970 Salivary secretion","KOG4220-Muscarinic acetylcholine receptor[T]"]
["MIR7476",108.97065,249.718872,1.19636524,{"v":1.35e-12,"d":"1.35E-12"},{"v":3.25e-12,"d":"3.25E-12"},"up","MIR7476","microRNA 7476","-","-","-"]
["PTPN4",8.885104,20.351614,1.195682645,{"v":2.02e-161,"d":"2.02E-161"},{"v":1.9e-160,"d":"1.90E-160"},"up","PTPN4","-","-","-","KOG0792-Protein tyrosine phosphatase PTPMEG, contains FERM domain[T]"]
["CCDC92B",2.988316,6.842875,1.195269879,{"v":1.03e-23,"d":"1.03E-23"},{"v":3.22e-23,"d":"3.22E-23"},"up","CCDC92B","-","-","-","-"]
["ENPP1",13.351292,30.558966,1.194616371,{"v":1.78e-167,"d":"1.78E-167"},{"v":1.71e-166,"d":"1.71E-166"},"up","ENPP1","-","GO:0003824;GO:0004527;GO:0004528;GO:0004551;GO:0005044;GO:0005158;GO:0005524;GO:0005615;GO:0005886;GO:0006091;GO:0006796;GO:0006898;GO:0006955;GO:0008152;GO:0009143;GO:0009986;GO:0016020;GO:0016021;GO:0030247;GO:0030308;GO:0030505;GO:0030643;GO:0030730;GO:0031953;GO:0032869;GO:0042803;GO:0045599;GO:0045719;GO:0046325;GO:0046627;GO:0047429;GO:0050427;GO:0090305","K01513-ko00500 Starch and sucrose metabolism;ko00230 Purine metabolism;ko00760 Nicotinate and nicotinamide metabolism;ko00770 Pantothenate and CoA biosynthesis","-"]
["RNF19A",9.199,21.035057,1.193246784,{"v":5.66e-113,"d":"5.66E-113"},{"v":4.13e-112,"d":"4.13E-112"},"up","RNF19A","-","GO:0004842;GO:0016020;GO:0016021;GO:0016567;GO:0016740;GO:0046872;GO:0098686;GO:0098794;GO:0098978;GO:0099576","-","KOG1815-Predicted E3 ubiquitin ligase[O]"]
["SHTN1",7.350149,16.798946,1.192525317,{"v":3.8e-77,"d":"3.80E-77"},{"v":2.16e-76,"d":"2.16E-76"},"up","SHTN1","-","GO:0005737;GO:0005874;GO:0005875;GO:0015630;GO:0019894;GO:0030424;GO:0030426;GO:0031252;GO:0043204;GO:0044295;GO:0048471;GO:0048812;GO:0061163;GO:2000114;GO:2001222;GO:2001224","-","-"]
["RAB40B",4.835172,11.046795,1.191988746,{"v":6.77e-30,"d":"6.77E-30"},{"v":2.36e-29,"d":"2.36E-29"},"up","RAB40B","RAB40B, member RAS oncogene family","GO:0003924;GO:0005525;GO:0005768;GO:0005886;GO:0006904;GO:0008021;GO:0009306;GO:0016567;GO:0017157;GO:0030667;GO:0035556;GO:0072659","-","KOG0078-GTP-binding protein SEC4, small G protein superfamily, and related Ras family GTP-binding proteins[TU]"]
["CENPV",193.716919,442.537506,1.191849769,0,0,"up","CENPV","-","GO:0008152;GO:0016846","-","-"]
["ZSWIM7",16.11277,36.797531,1.191404435,{"v":1.47e-53,"d":"1.47E-53"},{"v":6.84e-53,"d":"6.84E-53"},"up","ZSWIM7","zinc finger SWIM-type containing 7","GO:0000724;GO:0008270;GO:0050821;GO:0097196","-","-"]
["UQCR10",267.198486,609.723572,1.190243489,0,0,"up","UQCR10","ubiquinol-cytochrome c reductase, complex III subunit X","GO:0005739;GO:0005743;GO:0005750;GO:0006122;GO:0008121;GO:0009060;GO:0034551","K00419-ko00190 Oxidative phosphorylation;ko04260 Cardiac muscle contraction;ko05010 Alzheimer's disease;ko05012 Parkinson's disease;ko05016 Huntington's disease;ko04932 Non-alcoholic fatty liver disease (NAFLD)","KOG3494-Ubiquinol cytochrome c oxidoreductase, subunit QCR9[C]"]
["CMTM8",10.347778,23.604807,1.189759679,{"v":2.14e-53,"d":"2.14E-53"},{"v":9.95e-53,"d":"9.95E-53"},"up","CMTM8","CKLF like MARVEL transmembrane domain containing 8","GO:0001766;GO:0005654;GO:0008104;GO:0016020;GO:0016021;GO:0019911;GO:0042552;GO:0045121","-","KOG4788-Members of chemokine-like factor super family and related proteins[V]"]
["IMMT",42.821949,97.623863,1.188883381,0,0,"up","IMMT","inner membrane mitochondrial protein","GO:0005739;GO:0005743;GO:0016020;GO:0016021;GO:0042407;GO:0043209;GO:0051560;GO:0061617","-","KOG1854-Mitochondrial inner membrane protein (mitofilin)[M]"]
["LOC107051846",3.59117,8.186844,1.188853456,{"v":2.5e-96,"d":"2.50E-96"},{"v":1.64e-95,"d":"1.64E-95"},"up","LOC107051846","-","-","K16172-ko04068 FoxO signaling pathway;ko04022 cGMP - PKG signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04152 AMPK signaling pathway;ko04150 mTOR signaling pathway;ko04910 Insulin signaling pathway;ko04923 Regulation of lipolysis in adipocyte;ko04920 Adipocytokine signaling pathway;ko04960 Aldosterone-regulated sodium reabsorption;ko04722 Neurotrophin signaling pathway;ko04211 Longevity regulating pathway - mammal;ko04212 Longevity regulating pathway - worm;ko04213 Longevity regulating pathway - multiple species;ko05206 MicroRNAs in cancer;ko04930 Type II diabetes mellitus;ko04932 Non-alcoholic fatty liver disease (NAFLD);ko04931 Insulin resistance","-"]
["WDR34",4.995075,11.38468,1.188515496,{"v":4.85e-25,"d":"4.85E-25"},{"v":1.55e-24,"d":"1.55E-24"},"up","WDR34","-","GO:0005829;GO:0005868;GO:0008574;GO:0042073;GO:0045503;GO:0045504;GO:0060271;GO:0097014","-","KOG1587-Cytoplasmic dynein intermediate chain[Z]"]
["LOC112531050",4.703121,10.716965,1.188206044,{"v":6.26e-27,"d":"6.26E-27"},{"v":2.07e-26,"d":"2.07E-26"},"up","LOC112531050","-","-","-","-"]
["ARL3",18.746183,42.71331,1.18808883,{"v":1.15e-222,"d":"1.15E-222"},{"v":1.38e-221,"d":"1.38E-221"},"up","ARL3","-","GO:0000166;GO:0005525;GO:0005622","-","KOG0074-GTP-binding ADP-ribosylation factor-like protein ARL3[R]"]
["NDUFS7",195.343262,445.011841,1.187832231,0,0,"up","NDUFS7","-","GO:0003954;GO:0005747;GO:0008137;GO:0016491;GO:0032981;GO:0046872;GO:0048038;GO:0051536;GO:0051539;GO:0055114","K03940-ko00190 Oxidative phosphorylation;ko05010 Alzheimer's disease;ko05012 Parkinson's disease;ko05016 Huntington's disease;ko04932 Non-alcoholic fatty liver disease (NAFLD)","KOG1687-NADH-ubiquinone oxidoreductase, NUFS7/PSST/20 kDa subunit[C]"]
["ACAD8",26.787958,60.919411,1.185317382,{"v":2.04e-134,"d":"2.04E-134"},{"v":1.68e-133,"d":"1.68E-133"},"up","ACAD8","acyl-CoA dehydrogenase family member 8","GO:0003995;GO:0006629;GO:0016491;GO:0016627;GO:0050660;GO:0055114","K11538-ko00280 Valine, leucine and isoleucine degradation","KOG0140-Medium-chain acyl-CoA dehydrogenase[I]"]
["MTFR1L",29.894918,67.879257,1.18307052,{"v":4.47e-144,"d":"4.47E-144"},{"v":3.86e-143,"d":"3.86E-143"},"up","MTFR1L","-","GO:0000266;GO:0005739;GO:0009060","-","-"]
["LPIN1",16.350077,37.121948,1.182974989,{"v":6.41e-291,"d":"6.41E-291"},{"v":9.46e-290,"d":"9.46E-290"},"up","LPIN1","-","GO:0003713;GO:0005634;GO:0005741;GO:0006357;GO:0008195;GO:0009062;GO:0016311;GO:0019432;GO:0045944","K15728-ko00561 Glycerolipid metabolism;ko00564 Glycerophospholipid metabolism","KOG2116-Protein involved in plasmid maintenance/nuclear protein involved in lipid metabolism[NI]"]
["TNFRSF9",4.168603,9.464444,1.182953773,{"v":1.67e-28,"d":"1.67E-28"},{"v":5.69e-28,"d":"5.69E-28"},"up","TNFRSF9","-","-","K05146-ko04060 Cytokine-cytokine receptor interaction","-"]
["SNN",4.813806,10.928206,1.182806678,{"v":2.76e-26,"d":"2.76E-26"},{"v":9.03e-26,"d":"9.03E-26"},"up","SNN","stannin","GO:0005737;GO:0005741;GO:0016020;GO:0016021;GO:0046872","-","-"]
["PITPNM2",4.150629,9.417303,1.181983965,{"v":7.42e-116,"d":"7.42E-116"},{"v":5.51e-115,"d":"5.51E-115"},"up","PITPNM2","-","GO:0005509;GO:0005548;GO:0005622;GO:0008526;GO:0015914;GO:0030971;GO:0046872;GO:0048015","-","-"]
["MX1",4.135555,9.382939,1.181958931,{"v":4.23e-30,"d":"4.23E-30"},{"v":1.48e-29,"d":"1.48E-29"},"up","MX1","MX dynamin like GTPase 1","-","K14754-ko05162 Measles;ko05164 Influenza A","KOG0446-Vacuolar sorting protein VPS1, dynamin, and related proteins[UR]"]
["WDR13L",46.353531,105.147942,1.181669467,{"v":5.73e-214,"d":"5.73E-214"},{"v":6.67e-213,"d":"6.67E-213"},"up","WDR13L","-","-","-","-"]
["GRHPR",3.658493,8.298259,1.181559188,{"v":3.61e-13,"d":"3.61E-13"},{"v":8.82e-13,"d":"8.82E-13"},"up","GRHPR","-","GO:0005737;GO:0005829;GO:0007588;GO:0008152;GO:0008465;GO:0016491;GO:0016616;GO:0016618;GO:0030267;GO:0042803;GO:0046487;GO:0051259;GO:0051287;GO:0055114;GO:0070402","K00049-ko00620 Pyruvate metabolism;ko00630 Glyoxylate and dicarboxylate metabolism;ko00260 Glycine, serine and threonine metabolism","KOG0069-Glyoxylate/hydroxypyruvate reductase (D-isomer-specific 2-hydroxy acid dehydrogenase superfamily)[C]"]
["ACOT13",56.848351,128.901871,1.181082798,{"v":2.87e-165,"d":"2.87E-165"},{"v":2.74e-164,"d":"2.74E-164"},"up","ACOT13","-","GO:0005737;GO:0005739;GO:0047617;GO:0051289;GO:0120163","-","KOG3328-HGG motif-containing thioesterase[R]"]
["TCAIM",17.835114,40.395161,1.179462043,{"v":1.38e-149,"d":"1.38E-149"},{"v":1.22e-148,"d":"1.22E-148"},"up","TCAIM","T-cell activation inhibitor, mitochondrial","GO:0005739","-","-"]
["RN7SL1",90.203156,204.294632,1.179401481,{"v":5.29e-74,"d":"5.29E-74"},{"v":2.95e-73,"d":"2.95E-73"},"up","RN7SL1","RNA, 7SL, cytoplasmic 1","-","-","-"]
["BRAT1",5.937892,13.446087,1.179163631,{"v":3.21e-49,"d":"3.21E-49"},{"v":1.44e-48,"d":"1.44E-48"},"up","BRAT1","-","GO:0006974;GO:0008283","-","-"]
["OSBPL5",20.652708,46.753159,1.178732886,{"v":3.07e-230,"d":"3.07E-230"},{"v":3.78e-229,"d":"3.78E-229"},"up","OSBPL5","-","GO:0001786;GO:0005548;GO:0006869;GO:0015485;GO:0015914;GO:0016020;GO:0016021;GO:0043231;GO:0070273","-","KOG2210-Oxysterol-binding protein[T]"]
["CCDC39",9.715231,21.986515,1.178298742,{"v":1.45e-198,"d":"1.45E-198"},{"v":1.57e-197,"d":"1.57E-197"},"up","CCDC39","-","GO:0003341;GO:0005930;GO:0007368;GO:0007507;GO:0036159;GO:0060285","-","-"]
["PTN",3.424633,7.749532,1.178159797,{"v":7.28e-67,"d":"7.28E-67"},{"v":3.82e-66,"d":"3.82E-66"},"up","PTN","pleiotrophin","GO:0001503;GO:0001756;GO:0005576;GO:0005615;GO:0005783;GO:0007420;GO:0007507;GO:0007612;GO:0008083;GO:0008201;GO:0008284;GO:0010469;GO:0019901;GO:0021915;GO:0030282;GO:0032991;GO:0035374;GO:0035989;GO:0043588;GO:0051216;GO:0051781;GO:0060173;GO:0061054;GO:0061056","-","-"]
["PARP14",8.781482,19.849865,1.176592855,{"v":1.32e-157,"d":"1.32E-157"},{"v":1.21e-156,"d":"1.21E-156"},"up","PARP14","-","GO:0003950;GO:0016740;GO:0016757","-","-"]
["MPV17",5.507317,12.436052,1.175106997,{"v":3.77e-16,"d":"3.77E-16"},{"v":1e-15,"d":"1.00E-15"},"up","MPV17","-","GO:0000002;GO:0005739;GO:0005743;GO:0016020;GO:0016021;GO:0034614;GO:0042592","K13348-ko04146 Peroxisome","KOG1944-Peroxisomal membrane protein MPV17 and related proteins[R]"]
["TMEM14CL",105.933273,239.104965,1.174488286,0,0,"up","TMEM14CL","transmembrane protein 14C-like","GO:0005739;GO:0005743;GO:0006839;GO:0016020;GO:0016021;GO:0030218;GO:0070453","-","KOG4267-Predicted membrane protein[S]"]
["ARL6",13.380436,30.173113,1.173138422,{"v":1.21e-51,"d":"1.21E-51"},{"v":5.52e-51,"d":"5.52E-51"},"up","ARL6","ADP ribosylation factor like GTPase 6","GO:0000166;GO:0005525;GO:0005622;GO:0005737;GO:0005829;GO:0005929;GO:0007420;GO:0008589;GO:0010842;GO:0016020;GO:0016055;GO:0045444;GO:0060271;GO:0061512;GO:0097499;GO:1903445;GO:0000166;GO:0005525","-","KOG0070-GTP-binding ADP-ribosylation factor Arf1[U]"]
["TULP4",3.792222,8.550885,1.173030321,{"v":4.13e-152,"d":"4.13E-152"},{"v":3.71e-151,"d":"3.71E-151"},"up","TULP4","-","GO:0005737;GO:0016567","-","KOG2503-Tubby superfamily protein TULP4[R]"]
["SPATA6",8.680976,19.531128,1.169846114,{"v":2.01e-143,"d":"2.01E-143"},{"v":1.73e-142,"d":"1.73E-142"},"up","SPATA6","-","GO:0007283;GO:0032027;GO:0044458;GO:0097224","-","-"]
["ARNTL",15.428258,34.69265,1.169054868,{"v":4.08e-103,"d":"4.08E-103"},{"v":2.78e-102,"d":"2.78E-102"},"up","ARNTL","aryl hydrocarbon receptor nuclear translocator like","GO:0000060;GO:0000976;GO:0000980;GO:0001190;GO:0003677;GO:0003700;GO:0005634;GO:0005654;GO:0005667;GO:0005737;GO:0006351;GO:0006355;GO:0006366;GO:0007283;GO:0007623;GO:0016604;GO:0016605;GO:0017162;GO:0032007;GO:0032922;GO:0033391;GO:0042176;GO:0042634;GO:0042753;GO:0043161;GO:0043231;GO:0043425;GO:0043565;GO:0045599;GO:0045892;GO:0045893;GO:0045944;GO:0046982;GO:0046983;GO:0048511;GO:0050767;GO:0050796;GO:0051726;GO:0051775;GO:0051879;GO:0060137;GO:0070491;GO:0070888;GO:0090263;GO:0090403;GO:0120163;GO:1901985;GO:2000074;GO:2000323;GO:2000772;GO:2001016","K02296-ko04728 Dopaminergic synapse;ko04710 Circadian rhythm;ko04711 Circadian rhythm - fly;ko05168 Herpes simplex infection","KOG3561-Aryl-hydrocarbon receptor nuclear translocator[K]"]
["SPG20",16.322634,36.695114,1.168714094,{"v":1e-184,"d":"1.00E-184"},{"v":1.03e-183,"d":"1.03E-183"},"up","SPG20","-","GO:0005737;GO:0005741;GO:0005811;GO:0005829;GO:0005886;GO:0009838;GO:0030496;GO:0030514;GO:0031625;GO:0034389;GO:0045202;GO:0048698;GO:0050905;GO:0051301;GO:0051881;GO:0060612","K19366-ko04144 Endocytosis","-"]
["CETN1",13.852003,31.0973,1.16669472,{"v":4.19e-81,"d":"4.19E-81"},{"v":2.46e-80,"d":"2.46E-80"},"up","CETN1","centrin 1","GO:0005509","-","KOG0028-Ca2+-binding protein (centrin/caltractin), EF-Hand superfamily protein[ZD]"]
["MFAP2",20.548172,46.123569,1.166494097,{"v":4.85e-40,"d":"4.85E-40"},{"v":1.96e-39,"d":"1.96E-39"},"up","MFAP2","-","GO:0001527;GO:0048048;GO:0048050","-","-"]
["TRMT13",5.48385,12.30665,1.166177084,{"v":9.03e-53,"d":"9.03E-53"},{"v":4.18e-52,"d":"4.18E-52"},"up","TRMT13","-","GO:0008033;GO:0008168;GO:0008175;GO:0030488;GO:0106050","-","KOG2811-Uncharacterized conserved protein[S]"]
["CAMK1D",9.733343,21.814392,1.164272963,{"v":1.8e-226,"d":"1.80E-226"},{"v":2.19e-225,"d":"2.19E-225"},"up","CAMK1D","-","GO:0004672;GO:0005524;GO:0005634;GO:0005737;GO:0006468;GO:0010976;GO:0032793;GO:0043065;GO:0043066;GO:0050766;GO:0050773;GO:0060267;GO:0071622;GO:0090023","-","KOG0032-Ca2+/calmodulin-dependent protein kinase, EF-Hand protein superfamily[T]"]
["DNMT3A",16.925516,37.925365,1.163963248,0,0,"up","DNMT3A","DNA methyltransferase 3 alpha","GO:0000122;GO:0000775;GO:0000791;GO:0000792;GO:0001046;GO:0003677;GO:0003682;GO:0003886;GO:0005623;GO:0005634;GO:0005654;GO:0005720;GO:0005737;GO:0006306;GO:0006325;GO:0006346;GO:0006349;GO:0006351;GO:0006355;GO:0007283;GO:0008168;GO:0009008;GO:0009408;GO:0010468;GO:0016363;GO:0016740;GO:0032259;GO:0042802;GO:0043045;GO:0043046;GO:0046872;GO:0071230;GO:0071774;GO:0090116","K17398-ko00270 Cysteine and methionine metabolism;ko05206 MicroRNAs in cancer","-"]
["CCDC34",9.627975,21.557863,1.162909872,{"v":1.06e-34,"d":"1.06E-34"},{"v":3.95e-34,"d":"3.95E-34"},"up","CCDC34","-","-","-","-"]
["MPC1",144.452576,323.295776,1.162258727,0,0,"up","MPC1","mitochondrial pyruvate carrier 1","GO:0005739;GO:0005743;GO:0006850;GO:0016020;GO:0016021;GO:0031305;GO:0050833;GO:0061732;GO:1990830","-","KOG1590-Uncharacterized conserved protein[S]"]
["SHISA4",45.341919,101.388741,1.160980097,{"v":2.43e-130,"d":"2.43E-130"},{"v":1.96e-129,"d":"1.96E-129"},"up","SHISA4","-","GO:0016020;GO:0016021","-","-"]
["PDXK",33.741287,75.440392,1.160822169,0,0,"up","PDXK","pyridoxal kinase","GO:0000287;GO:0005524;GO:0005654;GO:0005829;GO:0008270;GO:0008283;GO:0008478;GO:0009443;GO:0016310;GO:0030170;GO:0030955;GO:0031402;GO:0031403;GO:0042803;GO:0042823","K00868-ko00750 Vitamin B6 metabolism","KOG2599-Pyridoxal/pyridoxine/pyridoxamine kinase[H]"]
["KIAA1549",13.673184,30.56266,1.160420878,0,0,"up","KIAA1549","-","GO:0016020;GO:0016021","-","-"]
["PCMT1L",40.735703,91.010445,1.159738323,{"v":3.74e-165,"d":"3.74E-165"},{"v":3.57e-164,"d":"3.57E-164"},"up","PCMT1L","protein-L-isoaspartate (D-aspartate) O-methyltransferase-like","GO:0004719;GO:0006464;GO:0006479;GO:0008168;GO:0016740;GO:0032259","-","KOG1661-Protein-L-isoaspartate(D-aspartate) O-methyltransferase[O]"]
["PECAM1",139.135437,310.85141,1.15973521,0,0,"up","PECAM1","-","-","K06471-ko04514 Cell adhesion molecules (CAMs);ko04670 Leukocyte transendothelial migration;ko05144 Malaria","-"]
["CEP85L",8.15263,18.205561,1.159041752,{"v":2.88e-152,"d":"2.88E-152"},{"v":2.58e-151,"d":"2.58E-151"},"up","CEP85L","-","GO:0005813","-","-"]
["GGT7",3.481355,7.773803,1.158971612,{"v":2.17e-68,"d":"2.17E-68"},{"v":1.16e-67,"d":"1.16E-67"},"up","GGT7","-","GO:0006508;GO:0006751;GO:0016020;GO:0016021;GO:0036374;GO:1902883","K00681-ko00430 Taurine and hypotaurine metabolism;ko00460 Cyanoamino acid metabolism;ko00480 Glutathione metabolism","KOG2410-Gamma-glutamyltransferase[E]"]
["RASSF1",32.147453,71.710808,1.157486134,{"v":1.82e-109,"d":"1.82E-109"},{"v":1.3e-108,"d":"1.30E-108"},"up","RASSF1","-","GO:0005634;GO:0007050;GO:0007165;GO:0007265;GO:0015630;GO:0035556;GO:0046872;GO:0070507","-","KOG4239-Ras GTPase effector RASSF2[T]"]
["DNAJA3",52.881973,117.906067,1.156790047,0,0,"up","DNAJA3","-","GO:0000122;GO:0005524;GO:0005634;GO:0005739;GO:0005759;GO:0005829;GO:0005884;GO:0006264;GO:0006457;GO:0006915;GO:0006924;GO:0007005;GO:0007264;GO:0007528;GO:0007569;GO:0008285;GO:0009408;GO:0019897;GO:0030695;GO:0031072;GO:0031594;GO:0033077;GO:0042102;GO:0042645;GO:0043069;GO:0043231;GO:0045211;GO:0046872;GO:0050790;GO:0051082","-","KOG0715-Molecular chaperone (DnaJ superfamily)[O]"]
["OARD1",19.453032,43.36935,1.156680786,{"v":1.6e-87,"d":"1.60E-87"},{"v":9.86e-87,"d":"9.86E-87"},"up","OARD1","O-acyl-ADP-ribose deacylase 1","GO:0001883;GO:0019213;GO:0042278","-","-"]
["BAG3",121.972687,271.802429,1.156000224,0,0,"up","BAG3","-","GO:0000774;GO:0005634;GO:0005737;GO:0005829;GO:0005886;GO:0008625;GO:0010664;GO:0030018;GO:0034605;GO:0042307;GO:0044877;GO:0046827;GO:0050790;GO:0050821;GO:0051087;GO:0071260;GO:0097192;GO:0097201","-","KOG4361-BCL2-associated athanogene-like proteins and related BAG family chaperone regulators[T]"]
["RHOF",4.834608,10.766308,1.15505278,{"v":2.82e-11,"d":"2.82E-11"},{"v":6.47e-11,"d":"6.47E-11"},"up","RHOF","ras homolog family member F, filopodia associated","GO:0000166;GO:0003924;GO:0005525;GO:0005622;GO:0007015;GO:0007264;GO:0000166;GO:0003924;GO:0005525;GO:0005622;GO:0007264","-","KOG0393-Ras-related small GTPase, Rho type[R]"]
["ALDH1L2",27.298655,60.786434,1.154919515,0,0,"up","ALDH1L2","-","GO:0003824;GO:0004029;GO:0005634;GO:0005737;GO:0005739;GO:0006730;GO:0008152;GO:0009058;GO:0009258;GO:0016155;GO:0016491;GO:0016620;GO:0016742;GO:0055114","K00289-ko00670 One carbon pool by folate","KOG2452-Formyltetrahydrofolate dehydrogenase[F]"]
["ANKRD10",29.457863,65.580856,1.154621958,{"v":2.6e-205,"d":"2.60E-205"},{"v":2.94e-204,"d":"2.94E-204"},"up","ANKRD10","ankyrin repeat domain 10","GO:0060828","-","KOG4177-Ankyrin[M]"]
["ASTE1",4.144124,9.225213,1.15451505,{"v":8.64e-25,"d":"8.64E-25"},{"v":2.75e-24,"d":"2.75E-24"},"up","ASTE1","-","-","-","-"]
["ADAT1",12.091563,26.863558,1.151649653,{"v":5.22e-91,"d":"5.22E-91"},{"v":3.3e-90,"d":"3.30E-90"},"up","ADAT1","adenosine deaminase, tRNA specific 1","GO:0003723;GO:0004000;GO:0006396;GO:0008033;GO:0008251;GO:0003723;GO:0004000;GO:0006396;GO:0008033;GO:0008251;GO:0016787;GO:0046872","-","KOG2777-tRNA-specific adenosine deaminase 1[A]"]
["PLEK2",21.675268,48.115376,1.150448171,{"v":9.04e-99,"d":"9.04E-99"},{"v":6.02e-98,"d":"6.02E-98"},"up","PLEK2","pleckstrin 2","GO:0005622;GO:0035556","-","KOG0690-Serine/threonine protein kinase[T]"]
["C2",3.346014,7.427238,1.150382327,{"v":1.95e-22,"d":"1.95E-22"},{"v":5.92e-22,"d":"5.92E-22"},"up","C2","-","GO:0004252;GO:0005576;GO:0006508;GO:0006956;GO:0006958;GO:2000427","-","-"]
["CBY1",11.912821,26.436468,1.150014352,{"v":7.97e-38,"d":"7.97E-38"},{"v":3.11e-37,"d":"3.11E-37"},"up","CBY1","chibby family member 1, beta catenin antagonist","GO:0036064;GO:0045444;GO:0055007;GO:0060271;GO:0090090","-","-"]
["NDUFS6",147.525757,327.329132,1.149775145,{"v":1.21e-190,"d":"1.21E-190"},{"v":1.27e-189,"d":"1.27E-189"},"up","NDUFS6","-","GO:0005739;GO:0005743;GO:0005747;GO:0006120;GO:0006631;GO:0006936;GO:0010259;GO:0016020;GO:0022904;GO:0035264;GO:0055114;GO:0061458;GO:0070469;GO:0070584;GO:0072358","K03939-ko00190 Oxidative phosphorylation;ko05010 Alzheimer's disease;ko05012 Parkinson's disease;ko05016 Huntington's disease;ko04932 Non-alcoholic fatty liver disease (NAFLD)","KOG3456-NADH:ubiquinone oxidoreductase, NDUFS6/13 kDa subunit[C]"]
["FAM19A3",2.740269,6.078888,1.149489915,{"v":8.98e-12,"d":"8.98E-12"},{"v":2.1e-11,"d":"2.10E-11"},"up","FAM19A3","-","-","-","-"]
["ST3GAL4",17.751287,39.314869,1.147151421,{"v":1.82e-83,"d":"1.82E-83"},{"v":1.09e-82,"d":"1.09E-82"},"up","ST3GAL4","-","GO:0003836;GO:0005794;GO:0006486;GO:0008373;GO:0009101;GO:0009247;GO:0009312;GO:0016020;GO:0016021;GO:0016740;GO:0016757;GO:0030259;GO:0047288;GO:0050890;GO:0097503;GO:1990743","K03494-ko00601 Glycosphingolipid biosynthesis - lacto and neolacto series","KOG2692-Sialyltransferase[G]"]
["AGL",27.881725,61.673042,1.145320187,0,0,"up","AGL","-","GO:0003824;GO:0004133;GO:0004134;GO:0004135;GO:0005634;GO:0005737;GO:0005977;GO:0005978;GO:0005980;GO:0016234;GO:0030247;GO:0031593","K01196-ko00500 Starch and sucrose metabolism","KOG3625-Alpha amylase[G]"]
["MRPL15",43.942307,97.167549,1.144863964,{"v":1.39e-133,"d":"1.39E-133"},{"v":1.14e-132,"d":"1.14E-132"},"up","MRPL15","mitochondrial ribosomal protein L15","GO:0003735;GO:0005739;GO:0005762;GO:0006412;GO:0015934;GO:1990830;GO:0003735;GO:0005739;GO:0005762;GO:0005840;GO:0006412;GO:0015934","K02876-ko03010 Ribosome","KOG0846-Mitochondrial/chloroplast ribosomal protein L15/L10[J]"]
["KLHL24",10.594064,23.41083,1.143919955,{"v":8.98e-114,"d":"8.98E-114"},{"v":6.58e-113,"d":"6.58E-113"},"up","KLHL24","kelch like family member 24","GO:0005737;GO:0005912;GO:0016567;GO:0030057;GO:0031463;GO:0045109;GO:0051865;GO:2000312","-","KOG4441-Proteins containing BTB/POZ and Kelch domains, involved in regulatory/signal transduction processes[TR]"]
["ZNFX1",7.138739,15.760459,1.14256839,{"v":1.49e-123,"d":"1.49E-123"},{"v":1.15e-122,"d":"1.15E-122"},"up","ZNFX1","-","-","-","KOG1807-Helicases[L]"]
["ACOT2L",20.857771,46.001328,1.14109052,{"v":1.75e-180,"d":"1.75E-180"},{"v":1.78e-179,"d":"1.78E-179"},"up","ACOT2L","-","GO:0005737;GO:0006631;GO:0006637;GO:0016790;GO:0047617","K01068-ko00062 Fatty acid elongation;ko01040 Biosynthesis of unsaturated fatty acids","-"]
["HEBP2",41.208881,90.734077,1.138689197,0,0,"up","HEBP2","-","-","-","-"]
["ADGRF5",7.735616,17.026312,1.138177887,{"v":2.67e-119,"d":"2.67E-119"},{"v":2.02e-118,"d":"2.02E-118"},"up","ADGRF5","-","-","-","KOG4193-G protein-coupled receptors[T]"]
["NCAM1",4.808112,10.581591,1.138014153,{"v":2.35e-65,"d":"2.35E-65"},{"v":1.22e-64,"d":"1.22E-64"},"up","NCAM1","neural cell adhesion molecule 1","GO:0005515;GO:0005829;GO:0005886;GO:0007155;GO:0007156;GO:0016020;GO:0016021;GO:0099560","K06491-ko04514 Cell adhesion molecules (CAMs);ko05020 Prion diseases","KOG3513-Neural cell adhesion molecule L1[T]"]
["CMTM7",9.534719,20.980553,1.137790378,{"v":3.37e-83,"d":"3.37E-83"},{"v":2.01e-82,"d":"2.01E-82"},"up","CMTM7","CKLF like MARVEL transmembrane domain containing 7","GO:0002337;GO:0016020;GO:0016021","-","KOG4788-Members of chemokine-like factor super family and related proteins[V]"]
["LOC107057170",5.05159,11.092106,1.134723852,{"v":1.67e-49,"d":"1.67E-49"},{"v":7.49e-49,"d":"7.49E-49"},"up","LOC107057170","-","-","K13242-ko00220 Arginine biosynthesis;ko00330 Arginine and proline metabolism;ko04370 VEGF signaling pathway;ko04066 HIF-1 signaling pathway;ko04020 Calcium signaling pathway;ko04071 Sphingolipid signaling pathway;ko04022 cGMP - PKG signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04611 Platelet activation;ko04915 Estrogen signaling pathway;ko04921 Oxytocin signaling pathway;ko04931 Insulin resistance;ko04933 AGE-RAGE signaling pathway in diabetic complications","-"]
["C5H14orf159",14.838744,32.562416,1.133838763,{"v":1.29e-95,"d":"1.29E-95"},{"v":8.43e-95,"d":"8.43E-95"},"up","C5H14orf159","-","GO:0005759;GO:0006536;GO:0047820","-","-"]
["CPAMD8",3.909801,8.578668,1.13365848,{"v":4.44e-133,"d":"4.44E-133"},{"v":3.64e-132,"d":"3.64E-132"},"up","CPAMD8","-","GO:0001654;GO:0004866;GO:0005615;GO:0010951","-","KOG1366-Alpha-macroglobulin[O]"]
["MATN4",3.685807,8.081204,1.132589724,{"v":9.84e-27,"d":"9.84E-27"},{"v":3.25e-26,"d":"3.25E-26"},"up","MATN4","-","GO:0005509","-","KOG1214-Nidogen and related basement membrane protein proteins[MW]"]
["IVD",18.204359,39.91021,1.132473928,{"v":1.15e-131,"d":"1.15E-131"},{"v":9.3e-131,"d":"9.30E-131"},"up","IVD","isovaleryl-CoA dehydrogenase","GO:0003995;GO:0005654;GO:0005739;GO:0016491;GO:0016627;GO:0050660;GO:0055114","K00253-ko00280 Valine, leucine and isoleucine degradation","KOG0141-Isovaleryl-CoA dehydrogenase[EI]"]
["GDAP1L1",18.914436,41.462685,1.132325786,{"v":9.55e-61,"d":"9.55E-61"},{"v":4.76e-60,"d":"4.76E-60"},"up","GDAP1L1","-","GO:0004364;GO:0005737;GO:0006749;GO:0016020;GO:0016021","-","KOG4420-Uncharacterized conserved protein (Ganglioside-induced differentiation associated protein 1, GDAP1)[S]"]
["SCYL3",14.295468,31.323233,1.131675276,{"v":5.95e-112,"d":"5.95E-112"},{"v":4.3e-111,"d":"4.30E-111"},"up","SCYL3","SCY1 like pseudokinase 3","GO:0004672;GO:0005524;GO:0005737;GO:0005794;GO:0006468;GO:0030027","-","KOG1243-Protein kinase[R]"]
["SRP9",31.028572,67.915398,1.130141402,{"v":4.91e-274,"d":"4.91E-274"},{"v":6.89e-273,"d":"6.89E-273"},"up","SRP9","signal recognition particle 9","GO:0003723;GO:0005047;GO:0005737;GO:0005785;GO:0005786;GO:0006614;GO:0006616;GO:0008312;GO:0045900;GO:0048500","K03109-ko03060 Protein export","KOG3465-Signal recognition particle, subunit Srp9[U]"]
["TMEM216",5.967855,13.057998,1.129649337,{"v":6.33e-13,"d":"6.33E-13"},{"v":1.54e-12,"d":"1.54E-12"},"up","TMEM216","-","GO:0005929;GO:0016020;GO:0016021;GO:0035869;GO:0036038;GO:0060271","-","-"]
["SDCCAG8",4.444793,9.716077,1.128257691,{"v":1.38e-103,"d":"1.38E-103"},{"v":9.47e-103,"d":"9.47E-103"},"up","SDCCAG8","-","GO:0001764;GO:0005737;GO:0005813;GO:0005814;GO:0005911;GO:0007098;GO:0030010;GO:0031023;GO:0034451;GO:0035148","-","-"]
["PRDM8",6.379583,13.936031,1.127285708,{"v":1.41e-31,"d":"1.41E-31"},{"v":5.05e-31,"d":"5.05E-31"},"up","PRDM8","-","GO:0003676;GO:0005634","-","KOG2461-Transcription factor BLIMP-1/PRDI-BF1, contains C2H2-type Zn-finger and SET domains[K]"]
["SUSD1",3.977816,8.689351,1.127271884,{"v":4.62e-35,"d":"4.62E-35"},{"v":1.73e-34,"d":"1.73E-34"},"up","SUSD1","-","GO:0005509;GO:0016020;GO:0016021","-","-"]
["TCEA3",43.292683,94.363022,1.12409841,{"v":5.51e-225,"d":"5.51E-225"},{"v":6.65e-224,"d":"6.65E-224"},"up","TCEA3","-","GO:0006351","-","KOG1105-Transcription elongation factor TFIIS/Cofactor of enhancer-binding protein Sp1[K]"]
["SLCO2A1",15.299686,33.312183,1.122547855,{"v":3.11e-88,"d":"3.11E-88"},{"v":1.93e-87,"d":"1.93E-87"},"up","SLCO2A1","solute carrier organic anion transporter family member 2A1","GO:0005215;GO:0005886;GO:0006811;GO:0015132;GO:0015732;GO:0016020;GO:0016021;GO:0055085","-","KOG3626-Organic anion transporter[Q]"]
["COQ9",105.879601,230.504166,1.122368162,{"v":3.96e-274,"d":"3.96E-274"},{"v":5.56e-273,"d":"5.56E-273"},"up","COQ9","coenzyme Q9","GO:0005743;GO:0006120;GO:0006744;GO:0008289;GO:0042803","-","KOG2969-Uncharacterized conserved protein[S]"]
["ROBO4",5.752995,12.51818,1.121639705,{"v":3.56e-55,"d":"3.56E-55"},{"v":1.69e-54,"d":"1.69E-54"},"up","ROBO4","-","-","-","-"]
["ST6GALNAC4",30.805483,66.900055,1.118820241,{"v":1.5e-102,"d":"1.50E-102"},{"v":1.02e-101,"d":"1.02E-101"},"up","ST6GALNAC4","ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4","GO:0000139;GO:0001665;GO:0005794;GO:0006486;GO:0008373;GO:0009311;GO:0016020;GO:0016021;GO:0016740;GO:0016757;GO:0018279;GO:0097503","K03374-ko00604 Glycosphingolipid biosynthesis - ganglio series","KOG2692-Sialyltransferase[G]"]
["PCBP4",5.305562,11.521743,1.118781499,{"v":2.89e-49,"d":"2.89E-49"},{"v":1.3e-48,"d":"1.30E-48"},"up","PCBP4","-","GO:0003676;GO:0003723;GO:0003730;GO:0005829;GO:0043488","-","KOG2190-PolyC-binding proteins alphaCP-1 and related KH domain proteins[AR]"]
["SEC61A2",14.325074,31.10494,1.118601132,{"v":1.38e-84,"d":"1.38E-84"},{"v":8.38e-84,"d":"8.38E-84"},"up","SEC61A2","Sec61 translocon alpha 2 subunit","GO:0015031;GO:0016020;GO:0016021;GO:0043022","K10956-ko03060 Protein export;ko04141 Protein processing in endoplasmic reticulum;ko04145 Phagosome;ko05110 Vibrio cholerae infection","KOG1373-Transport protein Sec61, alpha subunit[UO]"]
["HMOX2",24.633366,53.487839,1.118597141,{"v":4.86e-106,"d":"4.86E-106"},{"v":3.38e-105,"d":"3.38E-105"},"up","HMOX2","-","GO:0004392;GO:0006788;GO:0006979;GO:0016020;GO:0016021;GO:0020037;GO:0042167;GO:0046872;GO:0055072;GO:0055114","-","KOG4480-Heme oxygenase[P]"]
["TMEM121L",6.106297,13.234219,1.115903392,{"v":2.05e-27,"d":"2.05E-27"},{"v":6.86e-27,"d":"6.86E-27"},"up","TMEM121L","-","-","-","-"]
["KCNQ1",6.225294,13.483883,1.115022137,{"v":7.53e-67,"d":"7.53E-67"},{"v":3.96e-66,"d":"3.96E-66"},"up","KCNQ1","-","-","K04926-ko04261 Adrenergic signaling in cardiomyocytes;ko04971 Gastric acid secretion;ko04972 Pancreatic secretion;ko04974 Protein digestion and absorption;ko04725 Cholinergic synapse;ko05110 Vibrio cholerae infection","KOG1419-Voltage-gated K+ channel KCNQ[P]"]
["MYH1A",17.070364,36.95533,1.114288635,{"v":8.73e-249,"d":"8.73E-249"},{"v":1.14e-247,"d":"1.14E-247"},"up","MYH1A","myosin, heavy chain 1A, skeletal muscle","GO:0000166;GO:0003774;GO:0003779;GO:0005524;GO:0016459;GO:0051015","K10352-ko04530 Tight junction","KOG0161-Myosin class II heavy chain[Z]"]
["MRPL38",25.916447,55.985634,1.111188731,{"v":4.64e-105,"d":"4.64E-105"},{"v":3.21e-104,"d":"3.21E-104"},"up","MRPL38","mitochondrial ribosomal protein L38","GO:0005739;GO:0005762","-","KOG3346-Phosphatidylethanolamine binding protein[R]"]
["GKAP1",10.621754,22.939234,1.110795195,{"v":9.42e-43,"d":"9.42E-43"},{"v":3.92e-42,"d":"3.92E-42"},"up","GKAP1","-","GO:0005794;GO:0007165;GO:0042802","-","-"]
["RECK",2.864874,6.186718,1.110702586,{"v":7.15e-159,"d":"7.15E-159"},{"v":6.62e-158,"d":"6.62E-158"},"up","RECK","-","GO:0001944;GO:0001955;GO:0004866;GO:0005886;GO:0008191;GO:0030198;GO:0030336;GO:0035115;GO:0060828;GO:1904684","-","-"]
["PBXIP1",19.602814,42.329304,1.110595998,{"v":4.32e-108,"d":"4.32E-108"},{"v":3.05e-107,"d":"3.05E-107"},"up","PBXIP1","-","-","-","-"]
["PARK2",6.425309,13.869429,1.110070652,{"v":7.64e-42,"d":"7.64E-42"},{"v":3.15e-41,"d":"3.15E-41"},"up","PARK2","-","GO:0000122;GO:0000151;GO:0000209;GO:0000422;GO:0000423;GO:0000976;GO:0001664;GO:0001933;GO:0001963;GO:0001964;GO:0003779;GO:0004842;GO:0005634;GO:0005737;GO:0005739;GO:0005783;GO:0005794;GO:0005829;GO:0006511;GO:0006513;GO:0007612;GO:0007626;GO:0008013;GO:0008344;GO:0010498;GO:0010506;GO:0010628;GO:0010629;GO:0010636;GO:0010821;GO:0010994;GO:0015631;GO:0016235;GO:0016567;GO:0016607;GO:0016740;GO:0019538;GO:0019899;GO:0019900;GO:0019901;GO:0030165;GO:0030544;GO:0031072;GO:0031396;GO:0031624;GO:0031625;GO:0031647;GO:0031648;GO:0032092;GO:0032232;GO:0032436;GO:0032991;GO:0033132;GO:0034976;GO:0035249;GO:0042053;GO:0042415;GO:0042417;GO:0042802;GO:0042826;GO:0043005;GO:0043123;GO:0043130;GO:0043161;GO:0043274;GO:0043388;GO:0043524;GO:0044257;GO:0044828;GO:0045944;GO:0046676;GO:0046872;GO:0046928;GO:0048471;GO:0050804;GO:0050821;GO:0051087;GO:0051582;GO:0051583;GO:0051865;GO:0051881;GO:0060548;GO:0061630;GO:0061734;GO:0070534;GO:0070585;GO:0070842;GO:0070936;GO:0070979;GO:0071797;GO:0085020;GO:0090090;GO:0090201;GO:0097237;GO:0097602;GO:0098779;GO:0098793;GO:0099073;GO:0099074;GO:1900407;GO:1901215;GO:1901800;GO:1902236;GO:1902254;GO:1902283;GO:1902530;GO:1903265;GO:1903377;GO:1903382;GO:1903542;GO:1903599;GO:1903861;GO:1904049;GO:1905366;GO:1905477;GO:1990381;GO:1990444;GO:1990452;GO:2000377;GO:2000378","K04556-ko04141 Protein processing in endoplasmic reticulum;ko04120 Ubiquitin mediated proteolysis;ko05012 Parkinson's disease","-"]
["MRPL39",20.60552,44.47514,1.109968275,{"v":1.46e-39,"d":"1.46E-39"},{"v":5.87e-39,"d":"5.87E-39"},"up","MRPL39","-","GO:0000166;GO:0005739;GO:0005762","-","KOG1637-Threonyl-tRNA synthetase[J]"]
["SLC25A11",111.367683,240.357498,1.109851161,0,0,"up","SLC25A11","-","GO:0016020;GO:0016021","-","KOG0759-Mitochondrial oxoglutarate/malate carrier proteins[C]"]
["ANKMY1",2.552639,5.507839,1.109496866,{"v":1.09e-13,"d":"1.09E-13"},{"v":2.69e-13,"d":"2.69E-13"},"up","ANKMY1","-","GO:0046872","-","-"]
["ARSH",5.241222,11.29663,1.10791733,{"v":1.33e-25,"d":"1.33E-25"},{"v":4.29e-25,"d":"4.29E-25"},"up","ARSH","arylsulfatase family, member H","GO:0003824;GO:0008152;GO:0008484;GO:0016020;GO:0016021","-","-"]
["TPSNRL",4.614134,9.94079,1.107300606,{"v":1.17e-20,"d":"1.17E-20"},{"v":3.43e-20,"d":"3.43E-20"},"up","TPSNRL","-","-","-","-"]
["DRAM2",39.261757,84.493721,1.105719398,{"v":1.09e-112,"d":"1.09E-112"},{"v":7.92e-112,"d":"7.92E-112"},"up","DRAM2","-","GO:0001917;GO:0005737;GO:0005764;GO:0005794;GO:0007601;GO:0010506;GO:0016020;GO:0016021;GO:0016324;GO:0043231;GO:0045494","-","KOG4320-Uncharacterized conserved protein[S]"]
["CLC2DL5",63.402237,136.348801,1.104696365,0,0,"up","CLC2DL5","-","-","-","-"]
["SENP8",11.210629,24.045797,1.100917519,{"v":2.44e-63,"d":"2.44E-63"},{"v":1.24e-62,"d":"1.24E-62"},"up","SENP8","SUMO/sentrin peptidase family member, NEDD8 specific","GO:0004175;GO:0005634;GO:0006508;GO:0008234;GO:0016926","-","KOG3246-Sentrin-specific cysteine protease (Ulp1 family)[R]"]
["SPATA7",3.012376,6.458659,1.100332796,{"v":1.74e-20,"d":"1.74E-20"},{"v":5.08e-20,"d":"5.08E-20"},"up","SPATA7","-","GO:0005654;GO:0005739;GO:0005829;GO:0005930;GO:0015630;GO:0032391;GO:0036064;GO:0045494;GO:1903546;GO:1903621","-","-"]
["MST1",25.175745,53.977112,1.100313318,{"v":5.26e-130,"d":"5.26E-130"},{"v":4.22e-129,"d":"4.22E-129"},"up","MST1","macrophage stimulating 1 (hepatocyte growth factor-like)","GO:0004252;GO:0005615;GO:0005773;GO:0006508;GO:0010628;GO:0010758;GO:0033601;GO:0046425;GO:1904036","-","KOG3627-Trypsin[E]"]
["SHMT1",3.45031,7.396277,1.100073267,{"v":7.21e-22,"d":"7.21E-22"},{"v":2.17e-21,"d":"2.17E-21"},"up","SHMT1","-","GO:0000900;GO:0003824;GO:0004372;GO:0005634;GO:0005829;GO:0006231;GO:0006544;GO:0006563;GO:0006565;GO:0006730;GO:0009113;GO:0016740;GO:0017148;GO:0019264;GO:0030170;GO:0035999;GO:0042802;GO:0042803;GO:0046653;GO:0046655;GO:0048027;GO:0051262;GO:0051289;GO:0070905;GO:1904482;GO:1990830","K00600-ko01200 Carbon metabolism;ko01230 Biosynthesis of amino acids;ko00630 Glyoxylate and dicarboxylate metabolism;ko00680 Methane metabolism;ko00260 Glycine, serine and threonine metabolism;ko00460 Cyanoamino acid metabolism;ko00670 One carbon pool by folate","KOG2467-Glycine/serine hydroxymethyltransferase[E]"]
["SYVN1",8.446932,18.10025,1.099510282,{"v":8.18e-52,"d":"8.18E-52"},{"v":3.74e-51,"d":"3.74E-51"},"up","SYVN1","-","-","K10601-ko04141 Protein processing in endoplasmic reticulum;ko04120 Ubiquitin mediated proteolysis","-"]
["CYTB",7772.492188,16652.46875,1.099286908,0,0,"up","CYTB","-","GO:0005739;GO:0005743;GO:0006122;GO:0008121;GO:0009055;GO:0016020;GO:0016021;GO:0016491;GO:0022904;GO:0031305;GO:0045275;GO:0046872;GO:0055114;GO:0070469;GO:0005739;GO:0005743;GO:0006122;GO:0008121;GO:0009055;GO:0016020;GO:0016021;GO:0016491;GO:0022900;GO:0022904;GO:0045275;GO:0046872;GO:0055114;GO:0070469","K00412-ko00190 Oxidative phosphorylation;ko02020 Two-component system;ko04260 Cardiac muscle contraction;ko05010 Alzheimer's disease;ko05012 Parkinson's disease;ko05016 Huntington's disease;ko04932 Non-alcoholic fatty liver disease (NAFLD)","KOG4663-Cytochrome b[C]"]
["TA3",7.798093,16.705677,1.099145184,{"v":1.26e-91,"d":"1.26E-91"},{"v":7.97e-91,"d":"7.97E-91"},"up","TA3","TALPID3","-","-","-"]
["PDGFC",14.518243,31.083002,1.098258977,{"v":6.01e-88,"d":"6.01E-88"},{"v":3.72e-87,"d":"3.72E-87"},"up","PDGFC","platelet derived growth factor C","GO:0005161;GO:0005576;GO:0005615;GO:0005829;GO:0005886;GO:0007171;GO:0007275;GO:0007596;GO:0008083;GO:0008284;GO:0009790;GO:0009887;GO:0009986;GO:0010469;GO:0014068;GO:0016020;GO:0030335;GO:0031954;GO:0042803;GO:0043406;GO:0048008;GO:0048146;GO:0048565;GO:0050730;GO:0051781;GO:0060348;GO:0070374;GO:0071230;GO:0120162","K05450-ko04014 Ras signaling pathway;ko04015 Rap1 signaling pathway;ko04072 Phospholipase D signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04060 Cytokine-cytokine receptor interaction;ko04810 Regulation of actin cytoskeleton;ko04510 Focal adhesion;ko04540 Gap junction;ko05231 Choline metabolism in cancer;ko05218 Melanoma;ko05215 Prostate cancer;ko01521 EGFR tyrosine kinase inhibitor resistance","-"]
["GAS8",13.444515,28.7824,1.098169183,{"v":8.72e-50,"d":"8.72E-50"},{"v":3.92e-49,"d":"3.92E-49"},"up","GAS8","growth arrest specific 8","GO:0003351;GO:0005737;GO:0005794;GO:0005874;GO:0005929;GO:0005930;GO:0007368;GO:0007420;GO:0008017;GO:0015630;GO:0017137;GO:0030317;GO:0031514;GO:0034613;GO:0035082;GO:0036064;GO:0036126;GO:0045880;GO:0048870;GO:0060294;GO:0097729;GO:1903566;GO:1904526","-","-"]
["LOC112531131",4.422254,9.464995,1.097819853,{"v":8.34e-08,"d":"8.34E-08"},{"v":1.66e-07,"d":"1.66E-07"},"up","LOC112531131","-","-","-","-"]
["COX3",16407.21484,35103.40625,1.097280669,0,0,"up","COX3","-","GO:0004129;GO:0005739;GO:0008535;GO:0015002;GO:0016020;GO:0016021;GO:0016491;GO:0019646;GO:0022904;GO:0045277;GO:0055114;GO:1902600;GO:0004129;GO:0005739;GO:0015002;GO:0016020;GO:0016021;GO:0016491;GO:0019646;GO:0022904;GO:0055114;GO:1902600","K02262-ko00190 Oxidative phosphorylation;ko04260 Cardiac muscle contraction;ko05010 Alzheimer's disease;ko05012 Parkinson's disease;ko05016 Huntington's disease;ko04932 Non-alcoholic fatty liver disease (NAFLD)","KOG4664-Cytochrome oxidase subunit III and related proteins[C]"]
["FGF2",4.225343,9.03908,1.097107483,{"v":3.95e-07,"d":"3.95E-07"},{"v":7.61e-07,"d":"7.61E-07"},"up","FGF2","fibroblast growth factor 2","GO:0000186;GO:0001525;GO:0001707;GO:0001759;GO:0001894;GO:0001934;GO:0001938;GO:0002089;GO:0003347;GO:0003407;GO:0005104;GO:0005178;GO:0005576;GO:0005615;GO:0005634;GO:0005730;GO:0005829;GO:0007275;GO:0007420;GO:0008083;GO:0008201;GO:0008283;GO:0008284;GO:0008285;GO:0008543;GO:0010001;GO:0010469;GO:0010595;GO:0010628;GO:0010756;GO:0014843;GO:0021762;GO:0021940;GO:0022008;GO:0030154;GO:0030324;GO:0042060;GO:0043536;GO:0045597;GO:0045669;GO:0045766;GO:0045944;GO:0046668;GO:0048678;GO:0048864;GO:0050679;GO:0051301;GO:0051726;GO:0051781;GO:0051897;GO:0060128;GO:0060129;GO:0060563;GO:0070374;GO:0070660;GO:0072089;GO:0072248;GO:0090050;GO:0090263","K18497-ko04014 Ras signaling pathway;ko04015 Rap1 signaling pathway;ko04010 MAPK signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04810 Regulation of actin cytoskeleton;ko04550 Signaling pathways regulating pluripotency of stem cells;ko05200 Pathways in cancer;ko05205 Proteoglycans in cancer;ko05218 Melanoma;ko05224 Breast cancer;ko01521 EGFR tyrosine kinase inhibitor resistance","KOG3885-Fibroblast growth factor[T]"]
["NDUFS2",62.582897,133.772339,1.095939483,{"v":1.36e-227,"d":"1.36E-227"},{"v":1.66e-226,"d":"1.66E-226"},"up","NDUFS2","-","GO:0003954;GO:0005654;GO:0005739;GO:0005747;GO:0006979;GO:0016491;GO:0016651;GO:0031625;GO:0042775;GO:0048038;GO:0051287;GO:0055114","K03935-ko00190 Oxidative phosphorylation;ko05010 Alzheimer's disease;ko05012 Parkinson's disease;ko05016 Huntington's disease;ko04932 Non-alcoholic fatty liver disease (NAFLD)","KOG2870-NADH:ubiquinone oxidoreductase, NDUFS2/49 kDa subunit[C]"]
["NUPL2",10.051445,21.484974,1.095925112,{"v":1.59e-34,"d":"1.59E-34"},{"v":5.95e-34,"d":"5.95E-34"},"up","NUPL2","nucleoporin like 2","GO:0046872;GO:0005049;GO:0005634;GO:0005643;GO:0015031;GO:0016020;GO:0031965;GO:0046872;GO:0051028;GO:0051168","K14321-ko03013 RNA transport","-"]
["QRSL1",11.667787,24.923635,1.09498354,{"v":1.72e-53,"d":"1.72E-53"},{"v":8.04e-53,"d":"8.04E-53"},"up","QRSL1","-","GO:0000166;GO:0004040;GO:0005524;GO:0005739;GO:0006412;GO:0016874;GO:0016884;GO:0030956;GO:0031647;GO:0032543;GO:0050567;GO:0070681","K02433-ko00970 Aminoacyl-tRNA biosynthesis","KOG1211-Amidases[J]"]
["LOC112532802",12.987431,27.643398,1.089818882,{"v":1.57e-15,"d":"1.57E-15"},{"v":4.1e-15,"d":"4.10E-15"},"up","LOC112532802","-","-","-","-"]
["LOC100859276",21.775511,46.309364,1.088597369,{"v":3.07e-91,"d":"3.07E-91"},{"v":1.94e-90,"d":"1.94E-90"},"up","LOC100859276","-","GO:0003676;GO:0003723;GO:0008270","-","-"]
["HSPA8",433.345703,921.184082,1.087971083,0,0,"up","HSPA8","heat shock 70kDa protein 8","GO:0000151;GO:0000166;GO:0000974;GO:0001664;GO:0001786;GO:0005524;GO:0005622;GO:0005634;GO:0005737;GO:0005770;GO:0005829;GO:0006457;GO:0007369;GO:0009792;GO:0016887;GO:0019899;GO:0030674;GO:0031072;GO:0031625;GO:0031647;GO:0042026;GO:0042623;GO:0043209;GO:0044788;GO:0044829;GO:0045892;GO:0046034;GO:0048026;GO:0048568;GO:0051082;GO:0051085;GO:0051087;GO:0051219;GO:0051726;GO:0055131;GO:0061077;GO:0061738;GO:0061740;GO:0070062;GO:0072318;GO:0098684;GO:0098690;GO:0098793;GO:0098978;GO:0099175;GO:0099634;GO:0101031;GO:1902904;GO:1990904;GO:0000166;GO:0005515;GO:0005524;GO:0005634;GO:0005737;GO:0007369;GO:0009792;GO:0048568;GO:0051219;GO:1990904","K03283-ko03040 Spliceosome;ko04141 Protein processing in endoplasmic reticulum;ko04010 MAPK signaling pathway;ko04144 Endocytosis;ko04612 Antigen processing and presentation;ko04915 Estrogen signaling pathway;ko04213 Longevity regulating pathway - multiple species;ko05134 Legionellosis;ko05162 Measles;ko05164 Influenza A;ko05169 Epstein-Barr virus infection;ko05145 Toxoplasmosis","KOG0101-Molecular chaperones HSP70/HSC70, HSP70 superfamily[O]"]
["FLNB",20.518015,43.611588,1.087820358,{"v":7.5e-96,"d":"7.50E-96"},{"v":4.9e-95,"d":"4.90E-95"},"up","FLNB","filamin B","GO:0001725;GO:0003334;GO:0003382;GO:0003779;GO:0005829;GO:0005886;GO:0005903;GO:0005925;GO:0007519;GO:0030036;GO:0030154;GO:0042802;GO:0045335;GO:0071346","K04437-ko04010 MAPK signaling pathway;ko04510 Focal adhesion;ko05205 Proteoglycans in cancer;ko05132 Salmonella infection","KOG0518-Actin-binding cytoskeleton protein, filamin[Z]"]
["EBF2",2.719282,5.779591,1.08774163,{"v":3.12e-19,"d":"3.12E-19"},{"v":8.91e-19,"d":"8.91E-19"},"up","EBF2","early B-cell factor 2","GO:0000978;GO:0001709;GO:0003677;GO:0003682;GO:0003700;GO:0005634;GO:0006351;GO:0006355;GO:0006366;GO:0007275;GO:0035563;GO:0045893;GO:0045944;GO:0046872;GO:0046983;GO:0060612;GO:0120162","-","KOG3836-HLH transcription factor EBF/Olf-1 and related DNA binding proteins[K]"]
["LOC112532542",3.094063,6.576038,1.087716063,{"v":8.77e-41,"d":"8.77E-41"},{"v":3.58e-40,"d":"3.58E-40"},"up","LOC112532542","-","-","-","-"]
["NDUFV1",136.189972,289.431946,1.08760369,0,0,"up","NDUFV1","NADH:ubiquinone oxidoreductase core subunit V1","GO:0003954;GO:0005739;GO:0005743;GO:0005747;GO:0005829;GO:0008137;GO:0010181;GO:0016020;GO:0016491;GO:0016651;GO:0042775;GO:0046872;GO:0051287;GO:0051536;GO:0051539;GO:0055114;GO:0070469","K03942-ko00190 Oxidative phosphorylation;ko05010 Alzheimer's disease;ko05012 Parkinson's disease;ko05016 Huntington's disease;ko04932 Non-alcoholic fatty liver disease (NAFLD)","-"]
["NPR2",17.703051,37.580666,1.085992614,{"v":5.66e-152,"d":"5.66E-152"},{"v":5.07e-151,"d":"5.07E-151"},"up","NPR2","-","GO:0000166;GO:0004016;GO:0004383;GO:0004672;GO:0005524;GO:0005886;GO:0005887;GO:0006182;GO:0006468;GO:0007168;GO:0008074;GO:0009190;GO:0016020;GO:0016021;GO:0016829;GO:0016849;GO:0016941;GO:0017046;GO:0022414;GO:0035556;GO:0042562;GO:0042802;GO:0051447;GO:0060348;GO:0097011;GO:1900194","K12324-ko00230 Purine metabolism;ko04022 cGMP - PKG signaling pathway;ko04921 Oxytocin signaling pathway;ko04270 Vascular smooth muscle contraction","KOG1023-Natriuretic peptide receptor, guanylate cyclase[T]"]
["LIPE",2.436362,5.170706,1.085632769,{"v":4.45e-08,"d":"4.45E-08"},{"v":8.96e-08,"d":"8.96E-08"},"up","LIPE","-","-","-","-"]
["ALDH6A1",33.315907,70.694778,1.085392481,0,0,"up","ALDH6A1","-","GO:0004491;GO:0005654;GO:0005739;GO:0006210;GO:0006574;GO:0008152;GO:0016491;GO:0016620;GO:0055114","K00140-ko01200 Carbon metabolism;ko00640 Propanoate metabolism;ko00562 Inositol phosphate metabolism;ko00280 Valine, leucine and isoleucine degradation;ko00410 beta-Alanine metabolism","KOG2450-Aldehyde dehydrogenase[C]"]
["SPATA13",5.355614,11.359034,1.084716261,{"v":1.95e-64,"d":"1.95E-64"},{"v":1e-63,"d":"1.00E-63"},"up","SPATA13","-","GO:0005089;GO:0035023","K05769-ko04810 Regulation of actin cytoskeleton","-"]
["TMEM223",58.347664,123.714256,1.084264954,{"v":1.61e-103,"d":"1.61E-103"},{"v":1.1e-102,"d":"1.10E-102"},"up","TMEM223","-","GO:0016020;GO:0016021","-","-"]
["CDK5RAP1",14.986578,31.774256,1.084187345,{"v":5.51e-82,"d":"5.51E-82"},{"v":3.26e-81,"d":"3.26E-81"},"up","CDK5RAP1","-","GO:0003824;GO:0005737;GO:0005739;GO:0006400;GO:0016740;GO:0035597;GO:0035600;GO:0045736;GO:0045903;GO:0051536;GO:0051539;GO:0070131;GO:0070900","-","KOG2492-CDK5 activator-binding protein[T]"]
["NUDT1",10.693488,22.666903,1.08385478,{"v":3.28e-27,"d":"3.28E-27"},{"v":1.09e-26,"d":"1.09E-26"},"up","NUDT1","nudix hydrolase 1","GO:0003924;GO:0005634;GO:0005737;GO:0005739;GO:0005759;GO:0005829;GO:0006195;GO:0006203;GO:0006281;GO:0008413;GO:0016787;GO:0030515;GO:0035539;GO:0036219;GO:0042262;GO:0046061;GO:0047693;GO:0006281;GO:0008413","-","KOG3084-NADH pyrophosphatase I of the Nudix family of hydrolases[L]"]
["UNC119B",28.518261,60.433884,1.083471654,{"v":4.48e-212,"d":"4.48E-212"},{"v":5.17e-211,"d":"5.17E-211"},"up","UNC119B","-","GO:0005622;GO:0008289;GO:0030182;GO:0035869;GO:0042953;GO:0060271","-","KOG4037-Photoreceptor synaptic vesicle protein HRG4/UNC-119[UT]"]
["MEF2D",13.976562,29.609617,1.083056304,{"v":3.07e-174,"d":"3.07E-174"},{"v":3.04e-173,"d":"3.04E-173"},"up","MEF2D","myocyte enhancer factor 2D","GO:0000977;GO:0000978;GO:0000981;GO:0001649;GO:0001958;GO:0002062;GO:0003677;GO:0003700;GO:0005634;GO:0005654;GO:0005737;GO:0006351;GO:0006355;GO:0006366;GO:0007512;GO:0019899;GO:0033613;GO:0035914;GO:0042803;GO:0042826;GO:0043231;GO:0045893;GO:0045944;GO:0046982;GO:0046983;GO:1904707","K09262-ko04022 cGMP - PKG signaling pathway","KOG0014-MADS box transcription factor[K]"]
["NDUFA5",92.954842,196.893997,1.082817204,{"v":2.63e-238,"d":"2.63E-238"},{"v":3.32e-237,"d":"3.32E-237"},"up","NDUFA5","NADH:ubiquinone oxidoreductase subunit A5","GO:0005743;GO:0005747;GO:0008137;GO:0016651;GO:0022904;GO:0032981;GO:0045271","K03949-ko00190 Oxidative phosphorylation;ko05010 Alzheimer's disease;ko05012 Parkinson's disease;ko05016 Huntington's disease;ko04932 Non-alcoholic fatty liver disease (NAFLD)","KOG3365-NADH:ubiquinone oxidoreductase, NDUFA5/B13 subunit[C]"]
["FAM181B",8.137211,17.234812,1.082719256,{"v":1.48e-42,"d":"1.48E-42"},{"v":6.15e-42,"d":"6.15E-42"},"up","FAM181B","-","-","-","-"]
["ARRDC2",18.006523,38.115311,1.081851019,{"v":3.62e-84,"d":"3.62E-84"},{"v":2.18e-83,"d":"2.18E-83"},"up","ARRDC2","-","GO:0005886;GO:0031410","-","KOG3780-Thioredoxin binding protein TBP-2/VDUP1[R]"]
["TMEM100",16.887608,35.702198,1.0800479,{"v":7.43e-63,"d":"7.43E-63"},{"v":3.77e-62,"d":"3.77E-62"},"up","TMEM100","-","GO:0001525;GO:0001570;GO:0003197;GO:0003198;GO:0005783;GO:0005886;GO:0007219;GO:0016020;GO:0016021;GO:0030509;GO:0043204;GO:0043491;GO:0045603;GO:0048471;GO:0050848;GO:0051930;GO:0060842;GO:0071773;GO:2001214","-","-"]
["CLUAP1",9.608099,20.30489,1.07950429,{"v":8.49e-37,"d":"8.49E-37"},{"v":3.26e-36,"d":"3.26E-36"},"up","CLUAP1","clusterin associated protein 1","GO:0005654;GO:0043231","-","KOG3647-Predicted coiled-coil protein[R]"]
["LOC112532873",11.395394,24.074188,1.079036331,{"v":5.58e-39,"d":"5.58E-39"},{"v":2.22e-38,"d":"2.22E-38"},"up","LOC112532873","-","-","-","-"]
["CBFB",27.298859,57.641483,1.078266801,{"v":4.41e-149,"d":"4.41E-149"},{"v":3.9e-148,"d":"3.90E-148"},"up","CBFB","core-binding factor beta subunit","GO:0000122;GO:0000209;GO:0001503;GO:0001649;GO:0003713;GO:0005634;GO:0030098;GO:0030099;GO:0043371;GO:0043378;GO:0043565;GO:0045944;GO:0048469;GO:0060216;GO:1903508;GO:0003713;GO:0005634;GO:1903508","-","KOG4785-Transcription factor CBF, beta subunit[K]"]
["ATP6V0A1",26.526258,55.996696,1.077920534,{"v":9.99e-199,"d":"9.99E-199"},{"v":1.09e-197,"d":"1.09E-197"},"up","ATP6V0A1","ATPase H  transporting V0 subunit a1","GO:0000220;GO:0005737;GO:0005794;GO:0005829;GO:0005886;GO:0006811;GO:0007035;GO:0015078;GO:0015986;GO:0015991;GO:0016020;GO:0016021;GO:0016241;GO:0016471;GO:0016607;GO:0030659;GO:0031410;GO:0033179;GO:0042470;GO:0043231;GO:0046961;GO:0051117;GO:0070072;GO:1901998","K02154-ko00190 Oxidative phosphorylation;ko04145 Phagosome;ko04142 Lysosome;ko04966 Collecting duct acid secretion;ko04721 Synaptic vesicle cycle;ko05323 Rheumatoid arthritis;ko05110 Vibrio cholerae infection;ko05120 Epithelial cell signaling in Helicobacter pylori infection;ko05152 Tuberculosis","KOG2189-Vacuolar H+-ATPase V0 sector, subunit a[C]"]
["SDHA",87.178749,183.803909,1.076119043,0,0,"up","SDHA","succinate dehydrogenase complex flavoprotein subunit A","GO:0000104;GO:0005739;GO:0005743;GO:0005749;GO:0006099;GO:0006105;GO:0006121;GO:0008177;GO:0009055;GO:0009061;GO:0016020;GO:0016491;GO:0016627;GO:0022900;GO:0022904;GO:0045282;GO:0050660;GO:0055114","K00234-ko01200 Carbon metabolism;ko00020 Citrate cycle (TCA cycle);ko00190 Oxidative phosphorylation;ko05010 Alzheimer's disease;ko05012 Parkinson's disease;ko05016 Huntington's disease;ko04932 Non-alcoholic fatty liver disease (NAFLD)","KOG2403-Succinate dehydrogenase, flavoprotein subunit[C]"]
["LOC112532081",2.893111,6.091378,1.074146957,0.001591806,0.002416364,"up","LOC112532081","-","-","-","-"]
["C4HCXorf57",3.919734,8.251306,1.07386673,{"v":6.15e-94,"d":"6.15E-94"},{"v":3.96e-93,"d":"3.96E-93"},"up","C4HCXorf57","-","GO:0003697;GO:0005657;GO:2000042","-","-"]
["UQCRB",56.327473,118.553062,1.07362227,{"v":1.01e-237,"d":"1.01E-237"},{"v":1.28e-236,"d":"1.28E-236"},"up","UQCRB","ubiquinol-cytochrome c reductase binding protein","GO:0005739;GO:0005743;GO:0005750;GO:0006122;GO:0016020;GO:0055114;GO:0070469","K00417-ko00190 Oxidative phosphorylation;ko04260 Cardiac muscle contraction;ko05010 Alzheimer's disease;ko05012 Parkinson's disease;ko05016 Huntington's disease;ko04932 Non-alcoholic fatty liver disease (NAFLD)","KOG3440-Ubiquinol cytochrome c reductase, subunit QCR7[C]"]
["FAM46C",4.210938,8.858967,1.072996849,{"v":9.01e-21,"d":"9.01E-21"},{"v":2.65e-20,"d":"2.65E-20"},"up","FAM46C","family with sequence similarity 46 member C","-","-","-"]
["PHKA1",21.224373,44.637714,1.07254121,{"v":6.89e-201,"d":"6.89E-201"},{"v":7.64e-200,"d":"7.64E-200"},"up","PHKA1","-","GO:0003824;GO:0004689;GO:0005516;GO:0005886;GO:0005964;GO:0005975;GO:0005977;GO:0006468;GO:0016020","K07190-ko04020 Calcium signaling pathway;ko04910 Insulin signaling pathway;ko04922 Glucagon signaling pathway","KOG3635-Phosphorylase kinase[G]"]
["HTRA3",43.97353,92.248756,1.068894106,{"v":6.91e-264,"d":"6.91E-264"},{"v":9.45e-263,"d":"9.45E-263"},"up","HTRA3","-","GO:0001558;GO:0004175;GO:0004252;GO:0005520;GO:0005576;GO:0006508;GO:0008236;GO:0030512;GO:0030514","-","KOG1320-Serine protease[O]"]
["ENTPD4",12.173516,25.533024,1.0686185,{"v":5.08e-79,"d":"5.08E-79"},{"v":2.93e-78,"d":"2.93E-78"},"up","ENTPD4","-","GO:0006256;GO:0016020;GO:0016021;GO:0016787;GO:0030173;GO:0045134;GO:0097637","K12305-ko00230 Purine metabolism;ko00240 Pyrimidine metabolism;ko04142 Lysosome","KOG1386-Nucleoside phosphatase[F]"]
["TP73",5.271987,11.054657,1.068235544,{"v":4.97e-39,"d":"4.97E-39"},{"v":1.98e-38,"d":"1.98E-38"},"up","TP73","-","GO:0000122;GO:0000785;GO:0000978;GO:0000981;GO:0002039;GO:0003677;GO:0003682;GO:0003684;GO:0003690;GO:0003700;GO:0005634;GO:0005654;GO:0005667;GO:0005794;GO:0005829;GO:0006355;GO:0006366;GO:0006915;GO:0006974;GO:0006978;GO:0007050;GO:0007346;GO:0008134;GO:0010165;GO:0010332;GO:0010468;GO:0019901;GO:0030054;GO:0031571;GO:0034644;GO:0042771;GO:0042802;GO:0043231;GO:0043508;GO:0043524;GO:0043565;GO:0044212;GO:0045893;GO:0045944;GO:0051262;GO:0060044;GO:0071158;GO:0097371","K10148-ko04390 Hippo signaling pathway;ko04115 p53 signaling pathway;ko04722 Neurotrophin signaling pathway;ko05162 Measles","-"]
["FBXO31",12.302027,25.791391,1.067993536,{"v":2.11e-172,"d":"2.11E-172"},{"v":2.07e-171,"d":"2.07E-171"},"up","FBXO31","-","GO:0006974;GO:0019005;GO:0030332;GO:0031145;GO:0031146;GO:0031571;GO:0043025","-","-"]
["UCKL1",19.556858,40.991158,1.067638141,{"v":1.57e-83,"d":"1.57E-83"},{"v":9.4e-83,"d":"9.40E-83"},"up","UCKL1","uridine-cytidine kinase 1 like 1","GO:0000166;GO:0004849;GO:0005524;GO:0005829;GO:0006206;GO:0008152;GO:0009116;GO:0016301;GO:0016310;GO:0016740;GO:0043097;GO:0044206;GO:0044211","K00876-ko00240 Pyrimidine metabolism;ko00983 Drug metabolism - other enzymes","KOG4203-Armadillo/beta-Catenin/plakoglobin[TZ]"]
["PREX1",4.923832,10.311083,1.066342427,{"v":4.44e-127,"d":"4.44E-127"},{"v":3.51e-126,"d":"3.51E-126"},"up","PREX1","-","GO:0005085;GO:0005089;GO:0005543;GO:0005737;GO:0005829;GO:0005886;GO:0006469;GO:0007186;GO:0030217;GO:0030593;GO:0030676;GO:0032007;GO:0035023;GO:0035556;GO:0043547;GO:0045785;GO:0072593;GO:1900026","-","KOG3519-Invasion-inducing protein TIAM1/CDC24 and related RhoGEF GTPases[T]"]
["MMRN1",15.709428,32.89246,1.066126259,{"v":1.88e-163,"d":"1.88E-163"},{"v":1.78e-162,"d":"1.78E-162"},"up","MMRN1","-","GO:0007596;GO:0031012","-","-"]
["LOC428714",3.271881,6.850516,1.066092382,{"v":4.02e-33,"d":"4.02E-33"},{"v":1.47e-32,"d":"1.47E-32"},"up","LOC428714","-","GO:0000049;GO:0002949;GO:0003725;GO:0005737;GO:0006450;GO:0016020;GO:0016021;GO:0016779","-","-"]
["SURF6",21.529472,45.055519,1.065390899,{"v":8.79e-66,"d":"8.79E-66"},{"v":4.56e-65,"d":"4.56E-65"},"up","SURF6","surfeit 6","GO:0001652;GO:0003677;GO:0003723;GO:0005654;GO:0005730;GO:0042254","-","KOG2885-Uncharacterized conserved protein[S]"]
["PCTP",6.497708,13.580011,1.063481831,{"v":3.49e-28,"d":"3.49E-28"},{"v":1.18e-27,"d":"1.18E-27"},"up","PCTP","-","GO:0005829;GO:0008289;GO:0008525;GO:0015914;GO:0031210","-","KOG2761-START domain-containing proteins involved in steroidogenesis/phosphatidylcholine transfer[I]"]
["MED19",48.701077,101.612488,1.061052135,{"v":1.22e-110,"d":"1.22E-110"},{"v":8.76e-110,"d":"8.76E-110"},"up","MED19","-","GO:0003712;GO:0005634;GO:0006351;GO:0006355;GO:0006357;GO:0008134;GO:0016592;GO:0016604;GO:0045944","-","KOG4043-Uncharacterized conserved protein[S]"]
["C15orf61",12.452793,25.964983,1.060097924,{"v":3.13e-30,"d":"3.13E-30"},{"v":1.1e-29,"d":"1.10E-29"},"up","C15orf61","chromosome 15 open reading frame 61","-","-","-"]
["TIPARP",17.146282,35.736153,1.05948856,{"v":7.57e-109,"d":"7.57E-109"},{"v":5.37e-108,"d":"5.37E-108"},"up","TIPARP","-","GO:0001570;GO:0001822;GO:0003950;GO:0005634;GO:0006471;GO:0006807;GO:0008209;GO:0008210;GO:0008270;GO:0008585;GO:0009791;GO:0010629;GO:0030097;GO:0035326;GO:0045732;GO:0046872;GO:0048008;GO:0048705;GO:0048745;GO:0060021;GO:0060325;GO:0071407","-","-"]
["FAM13A",42.208424,87.950623,1.059162835,0,0,"up","FAM13A","-","GO:0007165","-","KOG1453-Chimaerin and related Rho GTPase activating proteins[T]"]
["CRYZL1",11.829039,24.622341,1.057635062,{"v":4.01e-46,"d":"4.01E-46"},{"v":1.74e-45,"d":"1.74E-45"},"up","CRYZL1","-","GO:0016491;GO:0055114","-","KOG1198-Zinc-binding oxidoreductase[CR]"]
["IL6R",15.488161,32.219955,1.056788624,{"v":6.04e-62,"d":"6.04E-62"},{"v":3.05e-61,"d":"3.05E-61"},"up","IL6R","interleukin 6 receptor","GO:0004896;GO:0004897;GO:0004915;GO:0005138;GO:0005576;GO:0005896;GO:0008284;GO:0016020;GO:0016021;GO:0016324;GO:0019221;GO:0019899;GO:0019981;GO:0031018;GO:0032722;GO:0032755;GO:0034097;GO:0042531;GO:0042803;GO:0048661;GO:0050731;GO:0070102;GO:0070110;GO:0070119;GO:0070120","K05055-ko04630 Jak-STAT signaling pathway;ko04066 HIF-1 signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04060 Cytokine-cytokine receptor interaction;ko04640 Hematopoietic cell lineage;ko04932 Non-alcoholic fatty liver disease (NAFLD);ko01521 EGFR tyrosine kinase inhibitor resistance","-"]
["NFE2L1",71.624588,148.957382,1.056372782,0,0,"up","NFE2L1","nuclear factor, erythroid 2 like 1","GO:0000980;GO:0001190;GO:0003677;GO:0003700;GO:0005634;GO:0005829;GO:0006351;GO:0006355;GO:0006366;GO:0016020;GO:0016021;GO:0019904;GO:0030218;GO:0032991;GO:0034599;GO:0044877;GO:0045944;GO:0000122;GO:0000976;GO:0000978;GO:0003677;GO:0003700;GO:0005634;GO:0005737;GO:0005783;GO:0005789;GO:0006351;GO:0006355;GO:0006357;GO:0006366;GO:0006629;GO:0008202;GO:0008203;GO:0008289;GO:0015485;GO:0016020;GO:0016021;GO:0030176;GO:0034599;GO:0036003;GO:0042632;GO:0045454;GO:0045893;GO:0055088;GO:0071397;GO:0097201;GO:1901329","-","KOG3863-bZIP transcription factor NRF1[K]"]
["ATP13A4",12.940992,26.845098,1.052710459,{"v":2.19e-125,"d":"2.19E-125"},{"v":1.72e-124,"d":"1.72E-124"},"up","ATP13A4","ATPase 13A4","GO:0000166;GO:0005524;GO:0006812;GO:0016020;GO:0016021;GO:0016787;GO:0016887;GO:0046872;GO:0000166;GO:0005388;GO:0005524;GO:0005887;GO:0006812;GO:0006874;GO:0016020;GO:0016021;GO:0016787;GO:0016887;GO:0043231;GO:0046872;GO:0070588;GO:0099132","-","KOG0208-Cation transport ATPase[P]"]
["THBD",17.339243,35.908783,1.050295844,{"v":7.65e-99,"d":"7.65E-99"},{"v":5.09e-98,"d":"5.09E-98"},"up","THBD","-","GO:0004888;GO:0005509;GO:0009986;GO:0016020;GO:0016021","K03907-ko04610 Complement and coagulation cascades;ko04933 AGE-RAGE signaling pathway in diabetic complications","-"]
["RCAN1",23.773417,49.226166,1.050076099,{"v":1.48e-173,"d":"1.48E-173"},{"v":1.46e-172,"d":"1.46E-172"},"up","RCAN1","regulator of calcineurin 1","GO:0003676;GO:0005737;GO:0008597;GO:0019722;GO:0033173;GO:0043666;GO:0070884","-","KOG4019-Calcineurin-mediated signaling pathway inhibitor DSCR1[TR]"]
["BAG1",8.532354,17.665541,1.049922204,{"v":1e-25,"d":"1.00E-25"},{"v":3.24e-25,"d":"3.24E-25"},"up","BAG1","BCL2 associated athanogene 1","GO:0051087","K09555-ko04141 Protein processing in endoplasmic reticulum","-"]
["CEP131",11.893204,24.58559,1.047675551,{"v":8.09e-91,"d":"8.09E-91"},{"v":5.1e-90,"d":"5.10E-90"},"up","CEP131","-","GO:0005813;GO:0005815;GO:0005929;GO:0008284;GO:0010824;GO:0015630;GO:0034451;GO:0035735;GO:0035869;GO:0042803;GO:0043231;GO:0044877;GO:0045171;GO:0060271;GO:0071539;GO:0090316","-","-"]
["MGARP",28.306768,58.514305,1.047642329,{"v":4.87e-155,"d":"4.87E-155"},{"v":4.42e-154,"d":"4.42E-154"},"up","MGARP","-","-","-","-"]
["STPG3",4.010414,8.289328,1.047503974,{"v":1.66e-07,"d":"1.66E-07"},{"v":3.25e-07,"d":"3.25E-07"},"up","STPG3","-","-","-","-"]
["EDIL3",6.19372,12.787616,1.045869258,{"v":1.03e-73,"d":"1.03E-73"},{"v":5.72e-73,"d":"5.72E-73"},"up","EDIL3","-","GO:0005178;GO:0005509;GO:0010811","-","[KOG3516-Neurexin IV[T], KOG1219-Uncharacterized conserved protein, contains laminin, cadherin and EGF domains[T]]"]
["CCDC15",6.422256,13.259156,1.045836866,{"v":6.24e-25,"d":"6.24E-25"},{"v":1.99e-24,"d":"1.99E-24"},"up","CCDC15","-","-","-","-"]
["FBXL2",14.828236,30.6089,1.045604218,{"v":7.03e-124,"d":"7.03E-124"},{"v":5.46e-123,"d":"5.46E-123"},"up","FBXL2","-","GO:0004842;GO:0006511;GO:0006513;GO:0010506;GO:0014066;GO:0016020;GO:0016567;GO:0019005;GO:0019903;GO:0031146;GO:0036312;GO:0044830","-","KOG4341-F-box protein containing LRR[R]"]
["PLK3",5.232462,10.797973,1.04519868,{"v":1.28e-30,"d":"1.28E-30"},{"v":4.52e-30,"d":"4.52E-30"},"up","PLK3","-","GO:0000082;GO:0000122;GO:0000166;GO:0000302;GO:0002039;GO:0004672;GO:0004674;GO:0005524;GO:0005634;GO:0005730;GO:0005737;GO:0005795;GO:0005813;GO:0006468;GO:0006970;GO:0006974;GO:0009314;GO:0016301;GO:0016310;GO:0016740;GO:0031122;GO:0032465;GO:0043066;GO:0051302;GO:0090166;GO:0090316;GO:1904716;GO:2000777","K08862-ko04068 FoxO signaling pathway;ko05152 Tuberculosis","KOG0575-Polo-like serine/threonine protein kinase[D]"]
["PTP4A2",41.01683,84.57148,1.043955229,{"v":1.13e-126,"d":"1.13E-126"},{"v":8.94e-126,"d":"8.94E-126"},"up","PTP4A2","-","GO:0004725;GO:0005634;GO:0005737;GO:0006470;GO:0008138;GO:0016311;GO:0016791;GO:0035335","-","KOG2836-Protein tyrosine phosphatase IVA1[T]"]
["LOC112530487",3.81641,7.868231,1.043823144,{"v":1.98e-59,"d":"1.98E-59"},{"v":9.77e-59,"d":"9.77E-59"},"up","LOC112530487","-","-","-","-"]
["RAPGEF1",16.696543,34.402302,1.04295568,{"v":2.86e-200,"d":"2.86E-200"},{"v":3.15e-199,"d":"3.15E-199"},"up","RAPGEF1","-","GO:0001568;GO:0005085;GO:0005737;GO:0005769;GO:0007264;GO:0010976;GO:0017034;GO:0032486;GO:0038180;GO:0043547;GO:0046580;GO:0048008;GO:0051898;GO:0061028;GO:0070373;GO:0071320;GO:0090090;GO:0098609;GO:1901888;GO:1990090;GO:2000178","K06277-ko04015 Rap1 signaling pathway;ko04510 Focal adhesion;ko04910 Insulin signaling pathway;ko04722 Neurotrophin signaling pathway;ko05211 Renal cell carcinoma","KOG3417-Ras1 guanine nucleotide exchange factor[T]"]
["ENTPD5",18.550205,38.212502,1.042609592,{"v":8.91e-167,"d":"8.91E-167"},{"v":8.55e-166,"d":"8.55E-166"},"up","ENTPD5","-","GO:0004382;GO:0005576;GO:0005783;GO:0006486;GO:0006487;GO:0008283;GO:0014066;GO:0016787;GO:0017110;GO:0045134;GO:0045821;GO:0046034;GO:0051084","K01511-ko00230 Purine metabolism;ko00240 Pyrimidine metabolism","KOG1385-Nucleoside phosphatase[F]"]
["LOC112532876",8.20717,16.905058,1.042498224,{"v":6.89e-21,"d":"6.89E-21"},{"v":2.04e-20,"d":"2.04E-20"},"up","LOC112532876","-","-","-","-"]
["TMEM198",5.012711,10.320137,1.041799157,{"v":1.91e-27,"d":"1.91E-27"},{"v":6.39e-27,"d":"6.39E-27"},"up","TMEM198","-","GO:0016020;GO:0016021","-","-"]
["LOC112530350",3.675513,7.564708,1.041338771,{"v":9.74e-24,"d":"9.74E-24"},{"v":3.04e-23,"d":"3.04E-23"},"up","LOC112530350","-","-","-","-"]
["PTPRE",2.752819,5.657579,1.03927507,{"v":8.32e-32,"d":"8.32E-32"},{"v":2.98e-31,"d":"2.98E-31"},"up","PTPRE","-","GO:0004721;GO:0004725;GO:0005634;GO:0005737;GO:0005886;GO:0006470;GO:0016020;GO:0016021;GO:0016311;GO:0016787;GO:0016791;GO:0035335","-","KOG4228-Protein tyrosine phosphatase[T]"]
["DNAJC28",5.692262,11.694114,1.038708589,{"v":8.03e-21,"d":"8.03E-21"},{"v":2.37e-20,"d":"2.37E-20"},"up","DNAJC28","-","-","-","KOG0568-Molecular chaperone (DnaJ superfamily)[O]"]
["CEP104",13.203013,27.112574,1.038094887,{"v":9.58e-110,"d":"9.58E-110"},{"v":6.84e-109,"d":"6.84E-109"},"up","CEP104","-","GO:0005814;GO:0016020;GO:0016021","-","KOG4825-Component of synaptic membrane glycine-, glutamate- and thienylcyclohexylpiperidine-binding glycoprotein (43kDa)[T]"]
["ZBTB45",6.388746,13.119234,1.038078799,{"v":7.07e-23,"d":"7.07E-23"},{"v":2.17e-22,"d":"2.17E-22"},"up","ZBTB45","-","GO:0003676","-","KOG3623-Homeobox transcription factor SIP1[K]"]
["OGDH",89.88298,184.499649,1.03749821,0,0,"up","OGDH","oxoglutarate dehydrogenase","GO:0004591;GO:0006099;GO:0008152;GO:0016624;GO:0030976;GO:0055114;GO:0004591;GO:0005634;GO:0005739;GO:0005829;GO:0006099;GO:0006103;GO:0006104;GO:0008152;GO:0016624;GO:0021695;GO:0021756;GO:0021766;GO:0021794;GO:0021860;GO:0022028;GO:0030976;GO:0034602;GO:0045252;GO:0055114;GO:0061034;GO:0106077","K00164-ko01200 Carbon metabolism;ko00020 Citrate cycle (TCA cycle);ko00310 Lysine degradation;ko00380 Tryptophan metabolism","[KOG0450-2-oxoglutarate dehydrogenase, E1 subunit[G], KOG2169-Zn-finger transcription factor[K]]"]
["HDX",2.657782,5.455122,1.037388687,{"v":1.98e-19,"d":"1.98E-19"},{"v":5.68e-19,"d":"5.68E-19"},"up","HDX","highly divergent homeobox","GO:0003677;GO:0005634;GO:0003677;GO:0005634","-","-"]
["SCRN3",23.565619,48.367455,1.037353051,{"v":3.99e-143,"d":"3.99E-143"},{"v":3.42e-142,"d":"3.42E-142"},"up","SCRN3","secernin 3","GO:0006508;GO:0016805","-","-"]
["PASD1",9.587339,19.673136,1.037024598,{"v":2.92e-118,"d":"2.92E-118"},{"v":2.19e-117,"d":"2.19E-117"},"up","PASD1","-","GO:0003677;GO:0003700;GO:0005634;GO:0005667;GO:0005737;GO:0006351;GO:0006355;GO:0046983","-","-"]
["FUT9",2.523377,5.176922,1.036738816,{"v":3.84e-74,"d":"3.84E-74"},{"v":2.14e-73,"d":"2.14E-73"},"up","FUT9","fucosyltransferase 9","-","K03663-ko00514 Other types of O-glycan biosynthesis;ko00601 Glycosphingolipid biosynthesis - lacto and neolacto series;ko00603 Glycosphingolipid biosynthesis - globo series","KOG2619-Fucosyltransferase[GE]"]
["LOC417013",15.804489,32.406384,1.03594366,{"v":2.91e-82,"d":"2.91E-82"},{"v":1.72e-81,"d":"1.72E-81"},"up","LOC417013","-","-","-","-"]
["CEP41",5.727987,11.733253,1.034502927,{"v":6.09e-26,"d":"6.09E-26"},{"v":1.98e-25,"d":"1.98E-25"},"up","CEP41","centrosomal protein 41","GO:0005737;GO:0005813;GO:0005814;GO:0005815;GO:0005856;GO:0005929;GO:0015031;GO:0018095;GO:0030030;GO:0036064;GO:0042995;GO:0060271","-","-"]
["C11H19orf12",7.891058,16.158606,1.034012094,{"v":1.12e-22,"d":"1.12E-22"},{"v":3.41e-22,"d":"3.41E-22"},"up","C11H19orf12","chromosome 11 C19orf12 homolog","-","-","-"]
["QPCT",7.258307,14.861214,1.033846989,{"v":1.45e-82,"d":"1.45E-82"},{"v":8.6e-82,"d":"8.60E-82"},"up","QPCT","-","GO:0008270;GO:0016603;GO:0017186","-","KOG3946-Glutaminyl cyclase[O]"]
["GSTAL2",80.327461,164.449265,1.033677379,{"v":3.6e-173,"d":"3.60E-173"},{"v":3.55e-172,"d":"3.55E-172"},"up","GSTAL2","-","GO:0004364;GO:0008152","K00799-ko00480 Glutathione metabolism;ko00980 Metabolism of xenobiotics by cytochrome P450;ko00982 Drug metabolism - cytochrome P450;ko05204 Chemical carcinogenesis;ko01524 Platinum drug resistance","-"]
["CD69L",39.606945,80.950386,1.031284534,{"v":5.99e-201,"d":"5.99E-201"},{"v":6.65e-200,"d":"6.65E-200"},"up","CD69L","-","-","-","-"]
["ZC2HC1A",6.418638,13.116087,1.030998273,{"v":4.19e-89,"d":"4.19E-89"},{"v":2.61e-88,"d":"2.61E-88"},"up","ZC2HC1A","-","-","-","KOG3940-Uncharacterized conserved protein[S]"]
["LOC107054608",3.800516,7.763135,1.030444068,{"v":2.91e-05,"d":"2.91E-05"},{"v":5.03e-05,"d":"5.03E-05"},"up","LOC107054608","-","-","-","-"]
["UQCRQ",331.487213,677.078491,1.030369869,{"v":1.98e-299,"d":"1.98E-299"},{"v":3e-298,"d":"3.00E-298"},"up","UQCRQ","-","GO:0005739;GO:0008121;GO:0021539;GO:0021548;GO:0021680;GO:0021766;GO:0021794;GO:0021854;GO:0021860;GO:0022900;GO:0030901","K00418-ko00190 Oxidative phosphorylation;ko04260 Cardiac muscle contraction;ko05010 Alzheimer's disease;ko05012 Parkinson's disease;ko05016 Huntington's disease;ko04932 Non-alcoholic fatty liver disease (NAFLD)","KOG4116-Ubiquinol cytochrome c reductase, subunit QCR8[C]"]
["SORBS2",14.524022,29.646751,1.029432987,{"v":1.37e-143,"d":"1.37E-143"},{"v":1.18e-142,"d":"1.18E-142"},"up","SORBS2","-","GO:0005654;GO:0007015","-","KOG4225-Sorbin and SH3 domain-containing protein[T]"]
["FOXO1",5.790963,11.80445,1.02745564,{"v":1.87e-68,"d":"1.87E-68"},{"v":9.98e-68,"d":"9.98E-68"},"up","FOXO1","forkhead box O1","GO:0000122;GO:0000981;GO:0001227;GO:0001568;GO:0003677;GO:0003700;GO:0005634;GO:0005737;GO:0006351;GO:0006355;GO:0006974;GO:0008013;GO:0008134;GO:0008286;GO:0009267;GO:0009653;GO:0010508;GO:0030154;GO:0031625;GO:0032869;GO:0032873;GO:0034599;GO:0035947;GO:0042127;GO:0042593;GO:0043065;GO:0043066;GO:0043565;GO:0045599;GO:0045722;GO:0045732;GO:0045893;GO:0045944;GO:0051721;GO:0071455;GO:0071732;GO:0090090;GO:0097150;GO:2000177;GO:2000377","K07201-ko04068 FoxO signaling pathway;ko04152 AMPK signaling pathway;ko04910 Insulin signaling pathway;ko04922 Glucagon signaling pathway;ko04919 Thyroid hormone signaling pathway;ko04211 Longevity regulating pathway - mammal;ko04213 Longevity regulating pathway - multiple species;ko05200 Pathways in cancer;ko05202 Transcriptional misregulation in cancers;ko05215 Prostate cancer;ko04931 Insulin resistance;ko04933 AGE-RAGE signaling pathway in diabetic complications","KOG4385-Predicted forkhead transcription factor[K]"]
["MRC2",35.653378,72.632431,1.026575096,0,0,"up","MRC2","-","GO:0004888;GO:0005518;GO:0005887;GO:0016020;GO:0016021;GO:0030246;GO:0030574","K06560-ko04145 Phagosome;ko05152 Tuberculosis","-"]
["UQCRFS1",184.645233,376.046814,1.026156257,0,0,"up","UQCRFS1","ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1","GO:0005739;GO:0005743;GO:0008121;GO:0016020;GO:0016491;GO:0016679;GO:0022900;GO:0051537;GO:0055114;GO:0070469;GO:0005739;GO:0005743;GO:0005750;GO:0005751;GO:0008121;GO:0016020;GO:0016021;GO:0016491;GO:0016679;GO:0022900;GO:0043209;GO:0046872;GO:0051536;GO:0051537;GO:0055114;GO:0070469","K00411-ko00190 Oxidative phosphorylation;ko02020 Two-component system;ko04260 Cardiac muscle contraction;ko05010 Alzheimer's disease;ko05012 Parkinson's disease;ko05016 Huntington's disease;ko04932 Non-alcoholic fatty liver disease (NAFLD)","KOG1671-Ubiquinol cytochrome c reductase, subunit RIP1[C]"]
["GSTA3",8.591077,17.495852,1.026102014,{"v":3.07e-17,"d":"3.07E-17"},{"v":8.37e-17,"d":"8.37E-17"},"up","GSTA3","glutathione S-transferase alpha 3","GO:0004364;GO:0008152;GO:0016740","K00799-ko00480 Glutathione metabolism;ko00980 Metabolism of xenobiotics by cytochrome P450;ko00982 Drug metabolism - cytochrome P450;ko05204 Chemical carcinogenesis;ko01524 Platinum drug resistance","KOG1695-Glutathione S-transferase[O]"]
["ADGRA1L",5.259605,10.701413,1.024774939,{"v":1.41e-74,"d":"1.41E-74"},{"v":7.9e-74,"d":"7.90E-74"},"up","ADGRA1L","-","GO:0004888;GO:0004930;GO:0007165;GO:0007166;GO:0007186;GO:0016020;GO:0016021","-","-"]
["CLIP1",23.681446,48.158569,1.024035349,{"v":5.69e-256,"d":"5.69E-256"},{"v":7.62e-255,"d":"7.62E-255"},"up","CLIP1","CAP-Gly domain containing linker protein 1","GO:0001578;GO:0005635;GO:0005813;GO:0005874;GO:0005881;GO:0008017;GO:0008270;GO:0015630;GO:0015631;GO:0016020;GO:0031116;GO:0035371;GO:0044354;GO:0044861;GO:0051010;GO:0001726;GO:0005737;GO:0005856;GO:0005874;GO:0008017;GO:0016020;GO:0030659;GO:0031410;GO:0035371;GO:0042995;GO:0046872","K10421-ko04150 mTOR signaling pathway","KOG4568-Cytoskeleton-associated protein and related proteins[ZR]"]
["RGCC",19.890213,40.436119,1.02358581,{"v":2.35e-76,"d":"2.35E-76"},{"v":1.33e-75,"d":"1.33E-75"},"up","RGCC","-","GO:0001100;GO:0001937;GO:0003331;GO:0005634;GO:0005730;GO:0005737;GO:0005813;GO:0006956;GO:0008285;GO:0010628;GO:0010718;GO:0016525;GO:0019901;GO:0030295;GO:0031659;GO:0032147;GO:0032967;GO:0043537;GO:0045840;GO:0045944;GO:0050710;GO:0050715;GO:0051091;GO:0051496;GO:0051726;GO:0070412;GO:0071158;GO:0071456;GO:0071850;GO:0072537;GO:0090272;GO:1901203;GO:1901991;GO:2000048;GO:2000353","-","-"]
["RBM38",70.960602,144.227448,1.023255597,0,0,"up","RBM38","RNA binding motif protein 38","GO:0003676;GO:0003723;GO:0003729;GO:0010830;GO:0043484;GO:0003676;GO:0003723;GO:0003729;GO:0005634;GO:0005737;GO:0005829;GO:0006397;GO:0008380;GO:0010830;GO:0030154;GO:0043484","-","KOG0149-Predicted RNA-binding protein SEB4 (RRM superfamily)[R]"]
["CS",91.838478,186.578857,1.022614872,0,0,"up","CS","-","GO:0004108;GO:0005739;GO:0005759;GO:0005975;GO:0006099;GO:0006101;GO:0016740;GO:0036440;GO:0046912","K01647-ko01200 Carbon metabolism;ko01210 2-Oxocarboxylic acid metabolism;ko01230 Biosynthesis of amino acids;ko00020 Citrate cycle (TCA cycle);ko00630 Glyoxylate and dicarboxylate metabolism","KOG2617-Citrate synthase[C]"]
["TMEM138",26.477419,53.753548,1.021597487,{"v":1.4e-48,"d":"1.40E-48"},{"v":6.21e-48,"d":"6.21E-48"},"up","TMEM138","transmembrane protein 138","GO:0005929;GO:0016020;GO:0016021;GO:0060271","-","-"]
["ND4",5000.48877,10148.50391,1.021126038,0,0,"up","ND4","-","GO:0005739;GO:0006120;GO:0008137;GO:0016020;GO:0016021;GO:0016491;GO:0042773;GO:0055114","K03881-ko00190 Oxidative phosphorylation;ko05012 Parkinson's disease","KOG4845-NADH dehydrogenase, subunit 4[C]"]
["ORAI2",20.447716,41.496571,1.021052423,{"v":4.44e-160,"d":"4.44E-160"},{"v":4.14e-159,"d":"4.14E-159"},"up","ORAI2","ORAI calcium release-activated calcium modulator 2","GO:0016020;GO:0016021;GO:0002115;GO:0015279;GO:0016020;GO:0016021;GO:0070588","K16057-ko04020 Calcium signaling pathway","KOG4298-CAP-binding protein complex interacting protein 2[A]"]
["ABCF2",30.017601,60.889671,1.020388836,{"v":4.83e-159,"d":"4.83E-159"},{"v":4.48e-158,"d":"4.48E-158"},"up","ABCF2","ATP binding cassette subfamily F member 2","GO:0000166;GO:0005524;GO:0016887","-","KOG0927-Predicted transporter (ABC superfamily)[R]"]
["HSD11B1a",5.222409,10.592355,1.020236026,{"v":1.41e-17,"d":"1.41E-17"},{"v":3.88e-17,"d":"3.88E-17"},"up","HSD11B1a","-","GO:0016491;GO:0055114","K15680-ko00140 Steroid hormone biosynthesis;ko00980 Metabolism of xenobiotics by cytochrome P450;ko05204 Chemical carcinogenesis","-"]
["RTN4RL2",49.148159,99.612236,1.019185592,{"v":1.5e-162,"d":"1.50E-162"},{"v":1.41e-161,"d":"1.41E-161"},"up","RTN4RL2","-","-","-","-"]
["GCNT3",14.739396,29.864964,1.018776577,{"v":1.97e-76,"d":"1.97E-76"},{"v":1.11e-75,"d":"1.11E-75"},"up","GCNT3","-","GO:0002426;GO:0008375;GO:0016020;GO:0047225;GO:0048729;GO:0050892;GO:0060993","K09662-ko00512 Mucin type O-glycan biosynthesis","KOG0799-Branching enzyme[G]"]
["LOC415664",15.572762,31.551123,1.018666511,{"v":1.56e-32,"d":"1.56E-32"},{"v":5.67e-32,"d":"5.67E-32"},"up","LOC415664","uncharacterized oxidoreductase-like","-","-","-"]
["NRG4",6.351052,12.863738,1.018242441,{"v":1.56e-32,"d":"1.56E-32"},{"v":5.66e-32,"d":"5.66E-32"},"up","NRG4","neuregulin 4","GO:0005102;GO:0005615;GO:0005622;GO:0016020;GO:0016021;GO:0035556;GO:0048513","K05458-ko04012 ErbB signaling pathway","-"]
["CTC1",3.239555,6.553145,1.016391803,{"v":3.33e-46,"d":"3.33E-46"},{"v":1.45e-45,"d":"1.45E-45"},"up","CTC1","-","GO:0000723;GO:0000784;GO:0003697;GO:0005634;GO:0032211;GO:0042162;GO:0098505;GO:1990879","-","-"]
["IQSEC1",15.113358,30.560349,1.015836774,{"v":1.12e-269,"d":"1.12E-269"},{"v":1.55e-268,"d":"1.55E-268"},"up","IQSEC1","-","-","K12495-ko04144 Endocytosis","KOG0931-Predicted guanine nucleotide exchange factor, contains Sec7 domain[U]"]
["MAP1LC3A",260.763458,527.127075,1.015409083,0,0,"up","MAP1LC3A","-","GO:0005737;GO:0006914","-","KOG1654-Microtubule-associated anchor protein involved in autophagy and membrane trafficking[Z]"]
["BOLA3",76.737083,155.027557,1.014528855,{"v":1.69e-61,"d":"1.69E-61"},{"v":8.5e-61,"d":"8.50E-61"},"up","BOLA3","-","-","-","-"]
["PDHA1",79.575417,160.727844,1.014225162,{"v":7.07e-241,"d":"7.07E-241"},{"v":8.99e-240,"d":"8.99E-240"},"up","PDHA1","pyruvate dehydrogenase (lipoamide) alpha 1","GO:0004739;GO:0006086;GO:0008152;GO:0016491;GO:0016624;GO:0043231;GO:0055114;GO:0004739;GO:0005739;GO:0006086;GO:0008152;GO:0016491;GO:0016624;GO:0043231;GO:0055114","K00161-ko01200 Carbon metabolism;ko00010 Glycolysis / Gluconeogenesis;ko00020 Citrate cycle (TCA cycle);ko00620 Pyruvate metabolism;ko04066 HIF-1 signaling pathway;ko04922 Glucagon signaling pathway;ko05230 Central carbon metabolism in cancer","KOG0225-Pyruvate dehydrogenase E1, alpha subunit[C]"]
["ATP5G1",259.301025,523.627991,1.013914311,0,0,"up","ATP5G1","-","GO:0000276;GO:0005739;GO:0006811;GO:0008289;GO:0015078;GO:0015986;GO:0015991;GO:0016020;GO:0016021;GO:0033177;GO:0045263;GO:0046933","K02128-ko00190 Oxidative phosphorylation;ko05010 Alzheimer's disease;ko05012 Parkinson's disease;ko05016 Huntington's disease","-"]
["SNTB1",31.029938,62.661137,1.013910134,{"v":1.79e-241,"d":"1.79E-241"},{"v":2.29e-240,"d":"2.29E-240"},"up","SNTB1","syntrophin beta 1","GO:0005198;GO:0032991;GO:0045202","-","KOG3551-Syntrophins (type beta)[W]"]
["SDHAF3",15.464054,31.222815,1.013682034,{"v":4.18e-30,"d":"4.18E-30"},{"v":1.46e-29,"d":"1.46E-29"},"up","SDHAF3","-","GO:0005739;GO:0005758;GO:0006105;GO:0006111;GO:0006979;GO:0034553","-","-"]
["MUL1L",16.918039,34.137497,1.012794929,{"v":6.5e-74,"d":"6.50E-74"},{"v":3.62e-73,"d":"3.62E-73"},"up","MUL1L","-","GO:0004842;GO:0006996;GO:0016020;GO:0016021;GO:0016567","-","-"]
["DIXDC1",20.614136,41.541203,1.010909001,{"v":2.99e-148,"d":"2.99E-148"},{"v":2.62e-147,"d":"2.62E-147"},"up","DIXDC1","-","GO:0005829;GO:0016055;GO:0019904;GO:0021795;GO:0021799;GO:0021846;GO:0021869;GO:0030177;GO:0032956;GO:0043015;GO:0045665;GO:0060070;GO:0070507;GO:0090263","-","KOG3571-Dishevelled 3 and related proteins[R]"]
["ARIH1",1862.938843,3751.089844,1.009729504,{"v":1.8e-59,"d":"1.80E-59"},{"v":8.89e-59,"d":"8.89E-59"},"up","ARIH1","ariadne RBR E3 ubiquitin protein ligase 1","GO:0000151;GO:0000209;GO:0004842;GO:0005737;GO:0006511;GO:0008270;GO:0016567;GO:0016604;GO:0016740;GO:0019005;GO:0031462;GO:0031463;GO:0031464;GO:0031624;GO:0031625;GO:0032436;GO:0046872;GO:0061630;GO:0097413","-","KOG1815-Predicted E3 ubiquitin ligase[O]"]
["MGP",1921.058716,3866.410156,1.009093075,0,0,"up","MGP","matrix Gla protein","GO:0001503;GO:0005201;GO:0005509;GO:0005576;GO:0007275;GO:0030154;GO:0031012;GO:0051216;GO:0062023","-","-"]
["ACKR3",60.353642,121.455498,1.008915062,{"v":1.21e-225,"d":"1.21E-225"},{"v":1.46e-224,"d":"1.46E-224"},"up","ACKR3","atypical chemokine receptor 3","GO:0001525;GO:0001570;GO:0004930;GO:0005044;GO:0005768;GO:0005886;GO:0005905;GO:0006935;GO:0007165;GO:0007186;GO:0009986;GO:0015026;GO:0016020;GO:0016021;GO:0016494;GO:0019956;GO:0019958;GO:0031623;GO:0043231;GO:0070098;GO:0070374;GO:1902230","K04304-ko04060 Cytokine-cytokine receptor interaction","KOG4219-G protein-coupled receptor[T]"]
["LOC101751423",49.174072,98.954887,1.008873132,{"v":4.1e-88,"d":"4.10E-88"},{"v":2.54e-87,"d":"2.54E-87"},"up","LOC101751423","-","GO:0016020;GO:0016021","-","-"]
["ESRRG",6.674743,13.424656,1.008100926,{"v":4.12e-19,"d":"4.12E-19"},{"v":1.17e-18,"d":"1.17E-18"},"up","ESRRG","estrogen related receptor gamma","GO:0000977;GO:0001228;GO:0003677;GO:0003700;GO:0003707;GO:0005496;GO:0005634;GO:0006351;GO:0006355;GO:0006366;GO:0008270;GO:0043401;GO:0043565;GO:0045893;GO:0045944;GO:0046872;GO:0120162","-","KOG4217-Nuclear receptors of the nerve growth factor-induced protein B type[K]"]
["GABARAPL1",45.40741,91.286064,1.007466882,{"v":7.3e-299,"d":"7.30E-299"},{"v":1.11e-297,"d":"1.11E-297"},"up","GABARAPL1","-","GO:0000045;GO:0000421;GO:0000422;GO:0005622;GO:0005737;GO:0005739;GO:0005776;GO:0005829;GO:0006914;GO:0006995;GO:0030957;GO:0031625","K08341-ko04068 FoxO signaling pathway;ko04140 Regulation of autophagy;ko04139 Regulation of mitophagy - yeast;ko04727 GABAergic synapse;ko04212 Longevity regulating pathway - worm","KOG1654-Microtubule-associated anchor protein involved in autophagy and membrane trafficking[Z]"]
["NKAIN4",18.781857,37.751945,1.007211263,{"v":3.05e-71,"d":"3.05E-71"},{"v":1.66e-70,"d":"1.66E-70"},"up","NKAIN4","-","GO:0002028;GO:0016020;GO:0016021","-","KOG4556-Predicted membrane protein[S]"]
["IDH3B",43.919964,88.231133,1.006410939,{"v":4.64e-166,"d":"4.64E-166"},{"v":4.45e-165,"d":"4.45E-165"},"up","IDH3B","isocitrate dehydrogenase 3 (NAD( )) beta","GO:0000287;GO:0004449;GO:0005739;GO:0006099;GO:0016616;GO:0051287;GO:0055114","K00030-ko01200 Carbon metabolism;ko01210 2-Oxocarboxylic acid metabolism;ko01230 Biosynthesis of amino acids;ko00020 Citrate cycle (TCA cycle)","KOG0784-Isocitrate dehydrogenase, gamma subunit[E]"]
["NDUFS8",113.764824,228.447998,1.005811253,{"v":4.55e-222,"d":"4.55E-222"},{"v":5.45e-221,"d":"5.45E-221"},"up","NDUFS8","-","GO:0016020;GO:0016651;GO:0051539;GO:0055114","K03941-ko00190 Oxidative phosphorylation;ko05010 Alzheimer's disease;ko05012 Parkinson's disease;ko05016 Huntington's disease;ko04932 Non-alcoholic fatty liver disease (NAFLD)","KOG3256-NADH:ubiquinone oxidoreductase, NDUFS8/23 kDa subunit[C]"]
["CRELD2",21.956526,44.081642,1.005528157,{"v":7.44e-73,"d":"7.44E-73"},{"v":4.11e-72,"d":"4.11E-72"},"up","CRELD2","cysteine-rich with EGF-like domains 2","GO:0005509;GO:0005615;GO:0005783;GO:0005794","-","KOG4260-Uncharacterized conserved protein[S]"]
["RAPGEF3",24.57069,49.325031,1.005381585,{"v":2.51e-148,"d":"2.51E-148"},{"v":2.21e-147,"d":"2.21E-147"},"up","RAPGEF3","-","GO:0005085;GO:0005886;GO:0005902;GO:0007264;GO:0017034;GO:0019904;GO:0030027;GO:0030175;GO:0030864;GO:0032486;GO:0033138;GO:0034242;GO:0035556;GO:0043547;GO:0045766;GO:0046827;GO:0051496;GO:0060143;GO:0061028;GO:0071320;GO:1901985;GO:2000249","K08014-ko04015 Rap1 signaling pathway;ko04072 Phospholipase D signaling pathway;ko04024 cAMP signaling pathway;ko04670 Leukocyte transendothelial migration;ko04261 Adrenergic signaling in cardiomyocytes;ko04726 Serotonergic synapse;ko04720 Long-term potentiation","KOG2378-cAMP-regulated guanine nucleotide exchange factor[T]"]
["DNLZ",21.36886,42.895653,1.00532151,{"v":6.04e-37,"d":"6.04E-37"},{"v":2.33e-36,"d":"2.33E-36"},"up","DNLZ","-","-","-","KOG3277-Uncharacterized conserved protein[S]"]
["C2H8ORF76",6.782383,13.614811,1.005312795,{"v":6.87e-49,"d":"6.87E-49"},{"v":3.07e-48,"d":"3.07E-48"},"up","C2H8ORF76","-","-","-","-"]
["MOG",5.844793,11.729578,1.004927274,{"v":2.49e-18,"d":"2.49E-18"},{"v":6.96e-18,"d":"6.96E-18"},"up","MOG","-","GO:0016020;GO:0016021","-","-"]
["BBS2",9.785108,19.635683,1.004818102,{"v":8.42e-49,"d":"8.42E-49"},{"v":3.75e-48,"d":"3.75E-48"},"up","BBS2","Bardet-Biedl syndrome 2","GO:0001103;GO:0005737;GO:0005815;GO:0005856;GO:0005886;GO:0005902;GO:0005929;GO:0007288;GO:0007601;GO:0008104;GO:0010629;GO:0014824;GO:0016020;GO:0021756;GO:0021766;GO:0021987;GO:0030534;GO:0031514;GO:0032420;GO:0033210;GO:0033365;GO:0034464;GO:0036064;GO:0038108;GO:0040015;GO:0040018;GO:0042311;GO:0042995;GO:0043001;GO:0044321;GO:0045444;GO:0045494;GO:0048854;GO:0051216;GO:0060170;GO:0060271;GO:0060296;GO:1905515","-","-"]
["PLCD4",14.273309,28.630062,1.004210959,{"v":8.59e-86,"d":"8.59E-86"},{"v":5.23e-85,"d":"5.23E-85"},"up","PLCD4","-","GO:0004435;GO:0004629;GO:0005509;GO:0005622;GO:0005829;GO:0005886;GO:0006629;GO:0007165;GO:0007340;GO:0008081;GO:0016042;GO:0016787;GO:0031965;GO:0035556;GO:0046488","K05857-ko00562 Inositol phosphate metabolism;ko04020 Calcium signaling pathway;ko04070 Phosphatidylinositol signaling system;ko04919 Thyroid hormone signaling pathway;ko04933 AGE-RAGE signaling pathway in diabetic complications","KOG0169-Phosphoinositide-specific phospholipase C[T]"]
["PROSC",27.063921,54.273964,1.003889411,{"v":1.93e-105,"d":"1.93E-105"},{"v":1.34e-104,"d":"1.34E-104"},"up","PROSC","-","GO:0005622;GO:0030170","-","-"]
["GLYATL3W",2.712982,5.428372,1.000640115,{"v":5.17e-07,"d":"5.17E-07"},{"v":9.9e-07,"d":"9.90E-07"},"up","GLYATL3W","-","GO:0005739;GO:0047961","-","-"]
["ARHGAP25",5.29725,2.64859,-1.000019064,{"v":8.92e-14,"d":"8.92E-14"},{"v":2.22e-13,"d":"2.22E-13"},"down","ARHGAP25","Rho GTPase activating protein 25","GO:0001891;GO:0005096;GO:0006911;GO:0007015;GO:0007165;GO:0043547;GO:0051058","-","KOG4270-GTPase-activator protein[T]"]
["RGS4",25.007915,12.499914,-1.000466611,{"v":2.89e-44,"d":"2.89E-44"},{"v":1.23e-43,"d":"1.23E-43"},"down","RGS4","regulator of G-protein signaling 4","GO:0005096;GO:0005634;GO:0005737;GO:0005886;GO:0007186;GO:0009968;GO:0043547","-","KOG3589-G protein signaling regulators[T]"]
["PTPN3",8.621095,4.308968,-1.000528739,{"v":1.52e-61,"d":"1.52E-61"},{"v":7.64e-61,"d":"7.64E-61"},"down","PTPN3","-","GO:0001784;GO:0004721;GO:0004725;GO:0005737;GO:0005856;GO:0006470;GO:0008092;GO:0009898;GO:0016311;GO:0016787;GO:0016791;GO:0017080;GO:0035335;GO:0045930;GO:0051045;GO:0051117;GO:0098902;GO:2000649","-","KOG0792-Protein tyrosine phosphatase PTPMEG, contains FERM domain[T]"]
["HSPA2",1016.021179,507.726074,-1.00080822,0,0,"down","HSPA2","heat shock 70kDa protein 2","-","K03283-ko03040 Spliceosome;ko04141 Protein processing in endoplasmic reticulum;ko04010 MAPK signaling pathway;ko04144 Endocytosis;ko04612 Antigen processing and presentation;ko04915 Estrogen signaling pathway;ko04213 Longevity regulating pathway - multiple species;ko05134 Legionellosis;ko05162 Measles;ko05164 Influenza A;ko05169 Epstein-Barr virus infection;ko05145 Toxoplasmosis","-"]
["RASSF6",18.964998,9.473966,-1.00129882,{"v":4.3e-54,"d":"4.30E-54"},{"v":2.01e-53,"d":"2.01E-53"},"down","RASSF6","-","GO:0007165;GO:0042981","-","KOG4239-Ras GTPase effector RASSF2[T]"]
["OLFML2B",104.293617,52.093639,-1.001471739,{"v":1.93e-250,"d":"1.93E-250"},{"v":2.53e-249,"d":"2.53E-249"},"down","OLFML2B","-","GO:0030198;GO:0031012;GO:0050840","-","KOG3545-Olfactomedin and related extracellular matrix glycoproteins[W]"]
["NCOA4",108.889404,54.388588,-1.001487695,{"v":8.45e-285,"d":"8.45E-285"},{"v":1.22e-283,"d":"1.22E-283"},"down","NCOA4","nuclear receptor coactivator 4","GO:0006622;GO:0006879;GO:0044754","K09289-ko05200 Pathways in cancer;ko05216 Thyroid cancer","-"]
["HMGCR",30.225246,15.096356,-1.001553732,{"v":9.99e-81,"d":"9.99E-81"},{"v":5.85e-80,"d":"5.85E-80"},"down","HMGCR","3-hydroxy-3-methylglutaryl-CoA reductase","GO:0004420;GO:0005778;GO:0005783;GO:0005789;GO:0006695;GO:0008299;GO:0008542;GO:0015936;GO:0016020;GO:0016021;GO:0016126;GO:0016491;GO:0016616;GO:0042282;GO:0043407;GO:0050661;GO:0050662;GO:0051262;GO:0055114;GO:0070402","K00021-ko00900 Terpenoid backbone biosynthesis;ko04152 AMPK signaling pathway;ko04976 Bile secretion","KOG2480-3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase[I]"]
["ADAM10",102.990227,51.432331,-1.001759997,0,0,"down","ADAM10","ADAM metallopeptidase domain 10","GO:0004175;GO:0004222;GO:0005634;GO:0005737;GO:0005794;GO:0005798;GO:0006468;GO:0006508;GO:0006509;GO:0007162;GO:0007219;GO:0007229;GO:0008233;GO:0008237;GO:0008284;GO:0009986;GO:0010820;GO:0014069;GO:0016020;GO:0016021;GO:0016485;GO:0019901;GO:0030307;GO:0030335;GO:0034612;GO:0042117;GO:0042803;GO:0051088;GO:0051089;GO:0097038;GO:0097197;GO:0098696;GO:0098978;GO:0099173;GO:0004222;GO:0006508;GO:0006509;GO:0007219;GO:0008237;GO:0016020;GO:0016021","-","KOG3658-Tumor necrosis factor-alpha-converting enzyme (TACE/ADAM17) and related metalloproteases[W]"]
["GCNT4",8.72806,4.356937,-1.002346767,{"v":2.03e-34,"d":"2.03E-34"},{"v":7.57e-34,"d":"7.57E-34"},"down","GCNT4","-","GO:0002121;GO:0008375;GO:0016020;GO:0042403;GO:0048729;GO:0048872;GO:0060993","K09663-ko00512 Mucin type O-glycan biosynthesis","KOG0799-Branching enzyme[G]"]
["SLC25A5",213.208054,106.367386,-1.003206073,{"v":2.24e-205,"d":"2.24E-205"},{"v":2.54e-204,"d":"2.54E-204"},"down","SLC25A5","-","GO:0005471;GO:0005739;GO:0005743;GO:0008284;GO:0015866;GO:0015867;GO:0016020;GO:0016021;GO:0022857;GO:0031625;GO:0042645;GO:0043209;GO:0046902;GO:0055085;GO:0071817;GO:1901029;GO:1990830","K05863-ko04020 Calcium signaling pathway;ko04022 cGMP - PKG signaling pathway;ko05012 Parkinson's disease;ko05016 Huntington's disease;ko05166 HTLV-I infection","KOG0749-Mitochondrial ADP/ATP carrier proteins[C]"]
["PTGER4",15.228857,7.595562,-1.003579045,{"v":2.31e-42,"d":"2.31E-42"},{"v":9.56e-42,"d":"9.56E-42"},"down","PTGER4","prostaglandin E receptor 4","-","K04261-ko04080 Neuroactive ligand-receptor interaction;ko04924 Renin secretion;ko04750 Inflammatory mediator regulation of TRP channels;ko05200 Pathways in cancer","-"]
["ATR",7.09965,3.539793,-1.004082907,{"v":1.51e-48,"d":"1.51E-48"},{"v":6.72e-48,"d":"6.72E-48"},"down","ATR","-","GO:0000077;GO:0000166;GO:0004672;GO:0004674;GO:0005524;GO:0005634;GO:0005654;GO:0005794;GO:0006281;GO:0006468;GO:0006974;GO:0008156;GO:0016301;GO:0016310;GO:0016605;GO:0016740;GO:0018105;GO:0032405;GO:0032407;GO:0034644;GO:0043517;GO:0046777;GO:0070198;GO:0071480;GO:0090399;GO:0097694;GO:1904884","K06640-ko03460 Fanconi anemia pathway;ko04110 Cell cycle;ko04214 Apoptosis - fly;ko04115 p53 signaling pathway;ko05166 HTLV-I infection","KOG0890-Protein kinase of the PI-3 kinase family involved in mitotic growth, DNA repair and meiotic recombination[TBLD]"]
["KIAA1671",66.315491,33.047565,-1.004801941,0,0,"down","KIAA1671","KIAA1671","-","-","-"]
["JMJD7",20.302202,10.117149,-1.004833415,{"v":1.25e-53,"d":"1.25E-53"},{"v":5.82e-53,"d":"5.82E-53"},"down","JMJD7","jumonji domain containing 7","-","-","KOG2508-Predicted phospholipase[I]"]
["SEC24D",21.220087,10.572974,-1.005049331,{"v":1.14e-121,"d":"1.14E-121"},{"v":8.79e-121,"d":"8.79E-121"},"down","SEC24D","-","GO:0000139;GO:0000149;GO:0006886;GO:0006888;GO:0008270;GO:0015031;GO:0030127;GO:0090110","K14007-ko04141 Protein processing in endoplasmic reticulum","KOG1984-Vesicle coat complex COPII, subunit SFB3[U]"]
["PAK5",6.978304,3.476605,-1.005197286,{"v":2.97e-24,"d":"2.97E-24"},{"v":9.37e-24,"d":"9.37E-24"},"down","PAK5","p21 (RAC1) activated kinase 5","GO:0000166;GO:0004672;GO:0004674;GO:0005524;GO:0005654;GO:0005737;GO:0005739;GO:0006468;GO:0006915;GO:0007010;GO:0007266;GO:0007346;GO:0007612;GO:0007613;GO:0007626;GO:0016301;GO:0016310;GO:0016477;GO:0016740;GO:0023014;GO:0030036;GO:0031098;GO:0032147;GO:0042981;GO:0043408;GO:0045202;GO:0048365;GO:2001237","K05736-ko04014 Ras signaling pathway;ko04012 ErbB signaling pathway;ko04810 Regulation of actin cytoskeleton;ko04510 Focal adhesion;ko04660 T cell receptor signaling pathway;ko04360 Axon guidance;ko05211 Renal cell carcinoma","KOG0578-p21-activated serine/threonine protein kinase[T]"]
["CLSTN1",89.140236,44.407677,-1.005267676,0,0,"down","CLSTN1","calsyntenin 1","GO:0001540;GO:0001558;GO:0005509;GO:0005576;GO:0007156;GO:0009986;GO:0014069;GO:0016020;GO:0016021;GO:0019894;GO:0042988;GO:0045211;GO:0050806;GO:0051965;GO:0090128;GO:0098845;GO:0098969;GO:0098978;GO:0099003","-","KOG1834-Calsyntenin[W]"]
["UBE2L3",264.92981,131.961487,-1.005493245,{"v":8.13e-222,"d":"8.13E-222"},{"v":9.72e-221,"d":"9.72E-221"},"down","UBE2L3","ubiquitin conjugating enzyme E2 L3","GO:0000166;GO:0005524;GO:0016740;GO:0000166;GO:0005524;GO:0016740","K04552-ko04120 Ubiquitin mediated proteolysis;ko05012 Parkinson's disease","-"]
["LONRF1",40.406651,20.125631,-1.005558766,{"v":2.03e-112,"d":"2.03E-112"},{"v":1.47e-111,"d":"1.47E-111"},"down","LONRF1","-","GO:0000209;GO:0005622;GO:0031624;GO:0032436;GO:0061630","-","KOG4159-Predicted E3 ubiquitin ligase[O]"]
["KRT20",63.569828,31.626751,-1.007196829,{"v":1.66e-87,"d":"1.66E-87"},{"v":1.03e-86,"d":"1.03E-86"},"down","KRT20","keratin 20","GO:0005198;GO:0005737;GO:0005829;GO:0005882;GO:0009267;GO:0045109;GO:0050708","-","KOG0977-Nuclear envelope protein lamin, intermediate filament superfamily[DY]"]
["COL6A3",92.52401,46.006371,-1.007994133,0,0,"down","COL6A3","collagen type VI alpha 3 chain","GO:0004867;GO:0005576;GO:0005581;GO:0005615;GO:0007155;GO:0010466;GO:0010951;GO:0030414;GO:0031012;GO:0042383","K06238-ko04151 PI3K-Akt signaling pathway;ko04512 ECM-receptor interaction;ko04510 Focal adhesion;ko04974 Protein digestion and absorption","KOG4295-Serine proteinase inhibitor (KU family)[O]"]
["DLG3",28.048975,13.935836,-1.0091485,{"v":8.14e-101,"d":"8.14E-101"},{"v":5.48e-100,"d":"5.48E-100"},"down","DLG3","-","GO:0001736;GO:0005737;GO:0005886;GO:0005911;GO:0005923;GO:0010923;GO:0019900;GO:0019902;GO:0031625;GO:0032281;GO:0045197;GO:0098978;GO:0099072","-","KOG0708-Membrane-associated guanylate kinase MAGUK (contains PDZ, SH3, HOOK and GUK domains)[F]"]
["RNF44",11.759046,5.839183,-1.009932589,{"v":1.16e-38,"d":"1.16E-38"},{"v":4.58e-38,"d":"4.58E-38"},"down","RNF44","-","GO:0016567;GO:0043161;GO:0061630","-","KOG4628-Predicted E3 ubiquitin ligase[O]"]
["ASB3",9.820899,4.869106,-1.012198186,{"v":4.04e-23,"d":"4.04E-23"},{"v":1.25e-22,"d":"1.25E-22"},"down","ASB3","ankyrin repeat and SOCS box containing 3","GO:0000151;GO:0004842;GO:0005634;GO:0005737;GO:0016020;GO:0016021;GO:0016567;GO:0031625;GO:0035556","-","KOG4177-Ankyrin[M]"]
["ARAP2",9.834147,4.873104,-1.012958908,{"v":1.63e-88,"d":"1.63E-88"},{"v":1.01e-87,"d":"1.01E-87"},"down","ARAP2","-","GO:0005096;GO:0005547;GO:0007165;GO:0043547;GO:0046872","K18440-ko04144 Endocytosis","KOG1117-Rho- and Arf-GTPase activating protein ARAP3[TZ]"]
["PRLR",11.672795,5.782942,-1.013274512,{"v":5.3e-92,"d":"5.30E-92"},{"v":3.37e-91,"d":"3.37E-91"},"down","PRLR","prolactin receptor","GO:0004896;GO:0004925;GO:0005886;GO:0007171;GO:0009986;GO:0016020;GO:0016021;GO:0017046;GO:0038161;GO:0046872","K05081-ko04630 Jak-STAT signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04080 Neuroactive ligand-receptor interaction;ko04060 Cytokine-cytokine receptor interaction;ko04917 Prolactin signaling pathway","KOG4221-Receptor mediating netrin-dependent axon guidance[T]"]
["ZYX",85.055374,42.092972,-1.014823016,{"v":3.95e-179,"d":"3.95E-179"},{"v":3.99e-178,"d":"3.99E-178"},"down","ZYX","zyxin","GO:0001725;GO:0005515;GO:0005623;GO:0005634;GO:0005737;GO:0005829;GO:0005856;GO:0005913;GO:0005925;GO:0007155;GO:0007160;GO:0007179;GO:0007229;GO:0030054;GO:0043149;GO:0045335;GO:0046872;GO:0051393;GO:0071346","K06273-ko04510 Focal adhesion","KOG1701-Focal adhesion adaptor protein Paxillin and related LIM proteins[T]"]
["AGPAT2",57.502724,28.440083,-1.015704625,{"v":1.36e-121,"d":"1.36E-121"},{"v":1.04e-120,"d":"1.04E-120"},"down","AGPAT2","-","GO:0001819;GO:0003841;GO:0005783;GO:0006629;GO:0006654;GO:0008152;GO:0008654;GO:0016020;GO:0016021;GO:0016411;GO:0016740;GO:0016746;GO:0046474","K13509-ko00561 Glycerolipid metabolism;ko00564 Glycerophospholipid metabolism;ko04072 Phospholipase D signaling pathway;ko04975 Fat digestion and absorption","KOG2848-1-acyl-sn-glycerol-3-phosphate acyltransferase[I]"]
["CLIC4",176.139389,86.99559,-1.017703392,0,0,"down","CLIC4","-","GO:0001525;GO:0001886;GO:0004364;GO:0005244;GO:0005254;GO:0005622;GO:0005634;GO:0005737;GO:0005739;GO:0005813;GO:0005829;GO:0005886;GO:0005902;GO:0005911;GO:0006749;GO:0006811;GO:0006821;GO:0007035;GO:0009566;GO:0009986;GO:0015630;GO:0016020;GO:0016363;GO:0030216;GO:0030336;GO:0030496;GO:0034220;GO:0034707;GO:0034765;GO:0035264;GO:0045177;GO:0048471;GO:0048754;GO:0061299;GO:0071277;GO:1902476","-","KOG1422-Intracellular Cl- channel CLIC, contains GST domain[P]"]
["NCOA5",11.56825,5.711891,-1.018130282,{"v":1.46e-47,"d":"1.46E-47"},{"v":6.43e-47,"d":"6.43E-47"},"down","NCOA5","-","GO:0003676;GO:0003682;GO:0003723;GO:0005634;GO:0015629;GO:0042593;GO:0046627","-","KOG0108-mRNA cleavage and polyadenylation factor I complex, subunit RNA15[A]"]
["MLF2",239.031754,118.008408,-1.018312631,{"v":5.6e-269,"d":"5.60E-269"},{"v":7.78e-268,"d":"7.78E-268"},"down","MLF2","myeloid leukemia factor 2","GO:0005634;GO:0006952;GO:0016020;GO:0016021","-","KOG4049-Proliferation-related protein MLF[S]"]
["LOC107051419",7.977959,3.938283,-1.018452924,{"v":8.38e-26,"d":"8.38E-26"},{"v":2.72e-25,"d":"2.72E-25"},"down","LOC107051419","-","-","-","-"]
["CDC42SE2",23.815859,11.74919,-1.019361286,{"v":3.29e-58,"d":"3.29E-58"},{"v":1.61e-57,"d":"1.61E-57"},"down","CDC42SE2","CDC42 small effector 2","GO:0005198;GO:0005886;GO:0007165;GO:0017048;GO:0035023","-","-"]
["SLC25A43",22.834669,11.263947,-1.019513426,{"v":4.66e-53,"d":"4.66E-53"},{"v":2.17e-52,"d":"2.17E-52"},"down","SLC25A43","-","GO:0005743;GO:0006839;GO:0016020;GO:0016021;GO:0022857;GO:0055085","-","KOG0752-Mitochondrial solute carrier protein[C]"]
["CDH20",5.158433,2.543622,-1.020048586,{"v":1.32e-13,"d":"1.32E-13"},{"v":3.26e-13,"d":"3.26E-13"},"down","CDH20","cadherin 20, type 2","GO:0005509;GO:0005886;GO:0007155;GO:0007156;GO:0016020;GO:0016021;GO:0046872","-","KOG4289-Cadherin EGF LAG seven-pass G-type receptor[T]"]
["PDZD11",82.116386,40.48494,-1.020284795,{"v":5.38e-99,"d":"5.38E-99"},{"v":3.59e-98,"d":"3.59E-98"},"down","PDZD11","PDZ domain containing 11","GO:0005737;GO:0005829;GO:0005911;GO:0007269;GO:0008022;GO:0016323;GO:0045199;GO:0045202;GO:0098793;GO:1903361","-","KOG3550-Receptor targeting protein Lin-7[W]"]
["HBEGF",13.456778,6.63035,-1.021176088,{"v":2.2e-10,"d":"2.20E-10"},{"v":4.89e-10,"d":"4.89E-10"},"down","HBEGF","heparin binding EGF like growth factor","GO:0005154;GO:0005515;GO:0005576;GO:0005615;GO:0005886;GO:0005887;GO:0007173;GO:0008016;GO:0008083;GO:0008201;GO:0008284;GO:0009986;GO:0010469;GO:0016020;GO:0016021;GO:0016477;GO:0021545;GO:0030335;GO:0035313;GO:0048661;GO:0050731;GO:0051549;GO:0051897;GO:0060326;GO:0090303","K08523-ko04012 ErbB signaling pathway;ko04912 GnRH signaling pathway;ko04915 Estrogen signaling pathway;ko05205 Proteoglycans in cancer;ko05219 Bladder cancer;ko05120 Epithelial cell signaling in Helicobacter pylori infection;ko01522 Endocrine resistance","-"]
["SLC27A4",34.063999,16.781994,-1.021333669,{"v":6.72e-102,"d":"6.72E-102"},{"v":4.56e-101,"d":"4.56E-101"},"down","SLC27A4","-","GO:0000038;GO:0001579;GO:0001676;GO:0003824;GO:0004467;GO:0005783;GO:0005789;GO:0005886;GO:0005902;GO:0006631;GO:0008152;GO:0015908;GO:0015909;GO:0016021;GO:0031526;GO:0031957;GO:0042760;GO:0043588;GO:0044539","K08745-ko03320 PPAR signaling pathway;ko04931 Insulin resistance","KOG1179-Very long-chain acyl-CoA synthetase/fatty acid transporter[I]"]
["CDA",12.325336,6.069761,-1.02191536,{"v":6.32e-14,"d":"6.32E-14"},{"v":1.58e-13,"d":"1.58E-13"},"down","CDA","cytidine deaminase","GO:0003824;GO:0004126;GO:0005829;GO:0008270;GO:0009972;GO:0016787;GO:0046872","K01489-ko00240 Pyrimidine metabolism;ko00983 Drug metabolism - other enzymes","KOG0833-Cytidine deaminase[F]"]
["PHYHD1",11.817214,5.819138,-1.022012584,{"v":3.73e-19,"d":"3.73E-19"},{"v":1.06e-18,"d":"1.06E-18"},"down","PHYHD1","-","-","-","-"]
["KCNN3",5.1202,2.520742,-1.0223517,{"v":1.27e-11,"d":"1.27E-11"},{"v":2.96e-11,"d":"2.96E-11"},"down","KCNN3","-","GO:0003714;GO:0005516;GO:0005737;GO:0005886;GO:0006813;GO:0015269;GO:0016020;GO:0016021;GO:0016286;GO:0030154;GO:0045892;GO:0046872;GO:0071805","-","KOG3684-Ca2+-activated K+ channel proteins (intermediate/small conductance classes)[P]"]
["SRD5A3",19.814079,9.748966,-1.023204793,{"v":2.54e-33,"d":"2.54E-33"},{"v":9.34e-33,"d":"9.34E-33"},"down","SRD5A3","-","GO:0003865;GO:0005737;GO:0005783;GO:0006488;GO:0006629;GO:0016020;GO:0016021;GO:0016095;GO:0016627;GO:0016628;GO:0019348;GO:0055114","K12345-ko00140 Steroid hormone biosynthesis","KOG1640-Predicted steroid reductase[I]"]
["ME1",73.333069,36.046528,-1.024603612,{"v":4.66e-118,"d":"4.66E-118"},{"v":3.5e-117,"d":"3.50E-117"},"down","ME1","malic enzyme 1","GO:0004470;GO:0004471;GO:0004473;GO:0005737;GO:0006108;GO:0008948;GO:0016491;GO:0030145;GO:0046872;GO:0051262;GO:0051287;GO:0055114;GO:1902031","K00029-ko01200 Carbon metabolism;ko00620 Pyruvate metabolism;ko00710 Carbon fixation in photosynthetic organisms","KOG1257-NADP+-dependent malic enzyme[C]"]
["MCCC2L",19.405968,9.536696,-1.024938964,{"v":4.71e-39,"d":"4.71E-39"},{"v":1.87e-38,"d":"1.87E-38"},"down","MCCC2L","methylcrotonoyl-Coenzyme A carboxylase 2-like","GO:0016874","K01969-ko00280 Valine, leucine and isoleucine degradation","KOG0540-3-Methylcrotonyl-CoA carboxylase, non-biotin containing subunit/Acetyl-CoA carboxylase carboxyl transferase, subunit beta[EI]"]
["THOC7",220.405243,108.206177,-1.026375685,{"v":6.66e-237,"d":"6.66E-237"},{"v":8.38e-236,"d":"8.38E-236"},"down","THOC7","THO complex 7","GO:0000346;GO:0000347;GO:0000445;GO:0000781;GO:0000784;GO:0005634;GO:0005737;GO:0005829;GO:0006397;GO:0006406;GO:0016607;GO:0046784","K13176-ko03013 RNA transport","KOG3215-Uncharacterized conserved protein[S]"]
["MTA3",10.231359,5.021347,-1.026851456,{"v":1.79e-11,"d":"1.79E-11"},{"v":4.14e-11,"d":"4.14E-11"},"down","MTA3","-","GO:0003677;GO:0003682;GO:0005634;GO:0005737;GO:0006355;GO:0008270;GO:0008284;GO:0010971;GO:0016581;GO:0043231;GO:0043565;GO:0044877;GO:0045892","-","KOG3554-Histone deacetylase complex, MTA1 component[B]"]
["PTBP2",40.933819,20.085331,-1.027151035,{"v":2.43e-101,"d":"2.43E-101"},{"v":1.64e-100,"d":"1.64E-100"},"down","PTBP2","-","GO:0003676;GO:0003723;GO:0003729;GO:0005634;GO:0005681;GO:0006376;GO:0006397;GO:0033119;GO:2000177","-","KOG1190-Polypyrimidine tract-binding protein[A]"]
["COX7A2",101.075073,49.586403,-1.027410764,{"v":9.88e-81,"d":"9.88E-81"},{"v":5.79e-80,"d":"5.79E-80"},"down","COX7A2","cytochrome c oxidase subunit 7A2","GO:0004129;GO:0005746;GO:0009055;GO:0016020;GO:0016021;GO:0022900;GO:1902600","K02270-ko00190 Oxidative phosphorylation;ko04260 Cardiac muscle contraction;ko05010 Alzheimer's disease;ko05012 Parkinson's disease;ko05016 Huntington's disease;ko04932 Non-alcoholic fatty liver disease (NAFLD)","-"]
["PKIG",72.91256,35.768024,-1.027496937,{"v":6.21e-61,"d":"6.21E-61"},{"v":3.1e-60,"d":"3.10E-60"},"down","PKIG","protein kinase (cAMP-dependent, catalytic) inhibitor gamma","GO:0000122;GO:0004862;GO:0006469;GO:0042308;GO:0071901","-","-"]
["REPS1",19.575653,9.602181,-1.027626397,{"v":4.63e-55,"d":"4.63E-55"},{"v":2.19e-54,"d":"2.19E-54"},"down","REPS1","RALBP1 associated Eps domain containing 1","GO:0005509;GO:0005886;GO:0005905;GO:0006898;GO:0017124","-","KOG1955-Ral-GTPase effector RALBP1[U]"]
["NUFIP1",26.50675,12.986026,-1.029399789,{"v":1.76e-66,"d":"1.76E-66"},{"v":9.19e-66,"d":"9.19E-66"},"down","NUFIP1","NUFIP1, FMR1 interacting protein 1","GO:0000492;GO:0001650;GO:0003676;GO:0003723;GO:0005634;GO:0005726;GO:0005730;GO:0008023;GO:0016363;GO:0022626;GO:0030515;GO:0030674;GO:0032991;GO:0042802;GO:0045202;GO:0045944;GO:0051117;GO:0051259;GO:0070761","-","-"]
["MOXD1",81.338654,39.841259,-1.029677879,{"v":3.35e-155,"d":"3.35E-155"},{"v":3.05e-154,"d":"3.05E-154"},"down","MOXD1","monooxygenase DBH like 1","GO:0003824;GO:0004497;GO:0004500;GO:0005507;GO:0005615;GO:0005783;GO:0005789;GO:0006589;GO:0016020;GO:0016021;GO:0016491;GO:0016715;GO:0030667;GO:0042420;GO:0042421;GO:0046872;GO:0055114;GO:0003824;GO:0004497;GO:0005507;GO:0005789;GO:0016715;GO:0055114","-","KOG3568-Dopamine beta-monooxygenase[E]"]
["EPN2",49.418118,24.201975,-1.029915286,{"v":5.09e-200,"d":"5.09E-200"},{"v":5.58e-199,"d":"5.58E-199"},"down","EPN2","epsin 2","GO:0006897;GO:0030128;GO:0030948;GO:0043231;GO:0045747;GO:1903671","K12471-ko04144 Endocytosis","KOG2056-Equilibrative nucleoside transporter protein[F]"]
["NOTCH2",40.806988,19.970617,-1.030937322,0,0,"down","NOTCH2","notch 2","GO:0003184;GO:0005509;GO:0005634;GO:0005654;GO:0005886;GO:0005887;GO:0006355;GO:0007050;GO:0007219;GO:0007275;GO:0009887;GO:0009986;GO:0010629;GO:0016020;GO:0016021;GO:0030154;GO:0038023;GO:0043235;GO:0045967;GO:0046579;GO:0046849;GO:0046872;GO:0050793;GO:0060413;GO:0070374;GO:2001204","-","KOG1217-Fibrillins and related proteins containing Ca2+-binding EGF-like domains[T]"]
["LOC421419",51.339077,25.117853,-1.031344206,{"v":1.75e-144,"d":"1.75E-144"},{"v":1.52e-143,"d":"1.52E-143"},"down","LOC421419","uncharacterized LOC421419","-","-","-"]
["LOC107054884",6.549341,3.203401,-1.031745344,{"v":7.69e-07,"d":"7.69E-07"},{"v":1.46e-06,"d":"1.46E-06"},"down","LOC107054884","-","-","-","-"]
["OSBPL2",130.684128,63.863628,-1.033017514,0,0,"down","OSBPL2","oxysterol binding protein like 2","GO:0006869;GO:0015485","-","KOG2209-Oxysterol-binding protein[T]"]
["VCL",124.478699,60.754185,-1.034843191,0,0,"down","VCL","vinculin","GO:0002009;GO:0002102;GO:0002162;GO:0003779;GO:0005198;GO:0005623;GO:0005737;GO:0005886;GO:0005903;GO:0005911;GO:0005912;GO:0005913;GO:0005915;GO:0005916;GO:0005925;GO:0007155;GO:0015629;GO:0030032;GO:0030334;GO:0031625;GO:0032991;GO:0034333;GO:0034394;GO:0042383;GO:0043034;GO:0043297;GO:0045294;GO:0048675;GO:0051015;GO:0090136;GO:0090636;GO:0090637;GO:1990357;GO:0001725;GO:0002009;GO:0002102;GO:0002162;GO:0003779;GO:0005198;GO:0005515;GO:0005623;GO:0005737;GO:0005743;GO:0005856;GO:0005886;GO:0005903;GO:0005911;GO:0005912;GO:0005913;GO:0005915;GO:0005916;GO:0005925;GO:0005927;GO:0007155;GO:0008013;GO:0015629;GO:0016020;GO:0017166;GO:0030018;GO:0030032;GO:0030054;GO:0030334;GO:0030486;GO:0031594;GO:0031625;GO:0032991;GO:0034333;GO:0034394;GO:0042383;GO:0042803;GO:0043034;GO:0043297;GO:0045294;GO:0045296;GO:0048675;GO:0051015;GO:0051371;GO:0051393;GO:0090136;GO:0090636;GO:0090637;GO:0097110;GO:0098723;GO:1990357","K05700-ko04810 Regulation of actin cytoskeleton;ko04510 Focal adhesion;ko04520 Adherens junction;ko04670 Leukocyte transendothelial migration;ko05131 Shigellosis;ko05100 Bacterial invasion of epithelial cells;ko05146 Amoebiasis","KOG3681-Alpha-catenin[W]"]
["GRB2",68.38179,33.373207,-1.034921859,{"v":4.32e-114,"d":"4.32E-114"},{"v":3.17e-113,"d":"3.17E-113"},"down","GRB2","growth factor receptor bound protein 2","GO:0001784;GO:0004715;GO:0005070;GO:0005102;GO:0005154;GO:0005168;GO:0005515;GO:0005634;GO:0005654;GO:0005730;GO:0005737;GO:0005768;GO:0005794;GO:0005886;GO:0005911;GO:0007169;GO:0007265;GO:0008180;GO:0008286;GO:0009967;GO:0012506;GO:0016020;GO:0016477;GO:0017124;GO:0019901;GO:0019903;GO:0019904;GO:0030154;GO:0030838;GO:0031234;GO:0031623;GO:0038083;GO:0042127;GO:0042770;GO:0042802;GO:0043408;GO:0043560;GO:0045087;GO:0046875;GO:0048646;GO:0070436;GO:0071479;GO:2000379","K04364-ko04014 Ras signaling pathway;ko04010 MAPK signaling pathway;ko04013 MAPK signaling pathway - fly;ko04012 ErbB signaling pathway;ko04630 Jak-STAT signaling pathway;ko04068 FoxO signaling pathway;ko04072 Phospholipase D signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04150 mTOR signaling pathway;ko04510 Focal adhesion;ko04540 Gap junction;ko04550 Signaling pathways regulating pluripotency of stem cells;ko04650 Natural killer cell mediated cytotoxicity;ko04660 T cell receptor signaling pathway;ko04662 B cell receptor signaling pathway;ko04664 Fc epsilon RI signaling pathway;ko04062 Chemokine signaling pathway;ko04910 Insulin signaling pathway;ko04912 GnRH signaling pathway;ko04915 Estrogen signaling pathway;ko04917 Prolactin signaling pathway;ko04722 Neurotrophin signaling pathway;ko04320 Dorso-ventral axis formation;ko04380 Osteoclast differentiation;ko05200 Pathways in cancer;ko05231 Choline metabolism in cancer;ko05206 MicroRNAs in cancer;ko05205 Proteoglycans in cancer;ko05203 Viral carcinogenesis;ko05214 Glioma;ko05221 Acute myeloid leukemia;ko05220 Chronic myeloid leukemia;ko05211 Renal cell carcinoma;ko05215 Prostate cancer;ko05213 Endometrial cancer;ko05224 Breast cancer;ko05223 Non-small cell lung cancer;ko05034 Alcoholism;ko05161 Hepatitis B;ko05160 Hepatitis C;ko01521 EGFR tyrosine kinase inhibitor resistance;ko01522 Endocrine resistance","KOG3601-Adaptor protein GRB2, contains SH2 and SH3 domains[T]"]
["AOC3",17.859722,8.716194,-1.034939411,{"v":3.82e-59,"d":"3.82E-59"},{"v":1.89e-58,"d":"1.89E-58"},"down","AOC3","-","GO:0005507;GO:0007601;GO:0008131;GO:0009308;GO:0016491;GO:0046872;GO:0048038;GO:0055114","K00276-ko00260 Glycine, serine and threonine metabolism;ko00350 Tyrosine metabolism;ko00360 Phenylalanine metabolism;ko00410 beta-Alanine metabolism;ko00950 Isoquinoline alkaloid biosynthesis;ko00960 Tropane, piperidine and pyridine alkaloid biosynthesis","-"]
["PAX9",90.355095,44.070198,-1.035802577,{"v":1.32e-132,"d":"1.32E-132"},{"v":1.08e-131,"d":"1.08E-131"},"down","PAX9","paired box 9","GO:0000977;GO:0001228;GO:0003677;GO:0003700;GO:0005634;GO:0006351;GO:0006355;GO:0006366;GO:0007275;GO:0007492;GO:0009887;GO:0042481;GO:0045892;GO:0045944;GO:0060325;GO:0071363","-","KOG3517-Transcription factor PAX1/9[K]"]
["CCNDBP1",67.216087,32.772705,-1.036311803,{"v":2.06e-73,"d":"2.06E-73"},{"v":1.14e-72,"d":"1.14E-72"},"down","CCNDBP1","-","GO:0005634;GO:0005654;GO:0051726","-","-"]
["PHLDB2",35.496628,17.304401,-1.03654298,{"v":1.33e-181,"d":"1.33E-181"},{"v":1.36e-180,"d":"1.36E-180"},"down","PHLDB2","-","GO:0000226;GO:0005829;GO:0005886;GO:0005925;GO:0010470;GO:0010717;GO:0031252;GO:0045111;GO:0045180;GO:0045184;GO:0051497;GO:0051895;GO:0070507;GO:1903690;GO:1904261","-","KOG1090-Predicted dual-specificity phosphatase[R]"]
["LOC101747310",40.664452,19.812483,-1.037358475,{"v":6.06e-45,"d":"6.06E-45"},{"v":2.59e-44,"d":"2.59E-44"},"down","LOC101747310","-","GO:0016020;GO:0016021","-","-"]
["ATP13A3",24.569447,11.956757,-1.039039242,{"v":2.08e-165,"d":"2.08E-165"},{"v":1.99e-164,"d":"1.99E-164"},"down","ATP13A3","-","GO:0000166;GO:0005388;GO:0005524;GO:0005887;GO:0006812;GO:0006874;GO:0016020;GO:0016021;GO:0016787;GO:0016887;GO:0043231;GO:0046872;GO:0070588;GO:0099132","-","KOG0208-Cation transport ATPase[P]"]
["LOC107054877",24.688215,12.01077,-1.039493887,{"v":3.88e-102,"d":"3.88E-102"},{"v":2.64e-101,"d":"2.64E-101"},"down","LOC107054877","-","-","-","-"]
["LDAH",39.276585,19.104023,-1.039793018,{"v":6.21e-94,"d":"6.21E-94"},{"v":4e-93,"d":"4.00E-93"},"down","LDAH","lipid droplet associated hydrolase","GO:0005811;GO:0019915;GO:0005783;GO:0005811;GO:0016298;GO:0016787;GO:0019915","-","KOG3975-Uncharacterized conserved protein[S]"]
["PMAIP1",7.261871,3.530125,-1.040622033,{"v":2.98e-06,"d":"2.98E-06"},{"v":5.47e-06,"d":"5.47E-06"},"down","PMAIP1","phorbol-12-myristate-13-acetate-induced protein 1","GO:0001836;GO:0006915;GO:0006919;GO:0006974","K10131-ko04210 Apoptosis;ko04215 Apoptosis - multiple species;ko04115 p53 signaling pathway;ko05203 Viral carcinogenesis;ko01524 Platinum drug resistance","-"]
["HPS4",8.781004,4.267805,-1.040891644,{"v":3.79e-26,"d":"3.79E-26"},{"v":1.24e-25,"d":"1.24E-25"},"down","HPS4","-","GO:0005085;GO:0005737;GO:0005764;GO:0006605;GO:0006996;GO:0007040;GO:0007596;GO:0016020;GO:0017137;GO:0030318;GO:0031085;GO:0031410;GO:0042470;GO:0042803;GO:0042827;GO:0046983;GO:0050821;GO:1903232","-","-"]
["HDAC1",49.378559,23.990746,-1.041406716,{"v":4.67e-133,"d":"4.67E-133"},{"v":3.82e-132,"d":"3.82E-132"},"down","HDAC1","histone deacetylase 1","GO:0000122;GO:0000785;GO:0000790;GO:0000978;GO:0001046;GO:0001085;GO:0001103;GO:0002039;GO:0003714;GO:0004407;GO:0005634;GO:0005654;GO:0005829;GO:0006325;GO:0006346;GO:0006351;GO:0006355;GO:0006476;GO:0008134;GO:0008284;GO:0010629;GO:0010870;GO:0016575;GO:0016580;GO:0016581;GO:0016787;GO:0019899;GO:0032041;GO:0032991;GO:0033558;GO:0033613;GO:0042826;GO:0043922;GO:0044212;GO:0045892;GO:0045893;GO:0045944;GO:0046872;GO:0047485;GO:0051059;GO:0060766;GO:0070491;GO:0070932;GO:0070933;GO:0090090;GO:0000118;GO:0004407;GO:0005634;GO:0005737;GO:0006325;GO:0006351;GO:0006355;GO:0008134;GO:0016575;GO:0016787;GO:0032041;GO:0070932","K06067-ko04330 Notch signaling pathway;ko04110 Cell cycle;ko04919 Thyroid hormone signaling pathway;ko04213 Longevity regulating pathway - multiple species;ko05200 Pathways in cancer;ko05202 Transcriptional misregulation in cancers;ko05203 Viral carcinogenesis;ko05220 Chronic myeloid leukemia;ko05016 Huntington's disease;ko05034 Alcoholism;ko05169 Epstein-Barr virus infection","KOG1342-Histone deacetylase complex, catalytic component RPD3[B]"]
["KCNE4",8.126098,3.947875,-1.041486452,{"v":2.1e-45,"d":"2.10E-45"},{"v":9.07e-45,"d":"9.07E-45"},"down","KCNE4","-","GO:0005249;GO:0006811;GO:0016020;GO:0016021;GO:0044325;GO:0071805","-","-"]
["APRT",34.721031,16.867712,-1.041545493,{"v":9.91e-32,"d":"9.91E-32"},{"v":3.55e-31,"d":"3.55E-31"},"down","APRT","adenine phosphoribosyltransferase","GO:0002055;GO:0003999;GO:0005654;GO:0005737;GO:0005829;GO:0006166;GO:0006168;GO:0007625;GO:0009116;GO:0016208;GO:0046083","K00759-ko00230 Purine metabolism","KOG1712-Adenine phosphoribosyl transferases[F]"]
["LOC112533143",7.320096,3.556152,-1.041545579,{"v":5.52e-15,"d":"5.52E-15"},{"v":1.42e-14,"d":"1.42E-14"},"down","LOC112533143","-","-","-","-"]
["ZNF598",52.288807,25.400919,-1.04162146,{"v":7.64e-126,"d":"7.64E-126"},{"v":6e-125,"d":"6.00E-125"},"down","ZNF598","-","GO:0003676","-","KOG2231-Predicted E3 ubiquitin ligase[O]"]
["LOC107054271",5.507305,2.673874,-1.042415025,{"v":2.25e-28,"d":"2.25E-28"},{"v":7.64e-28,"d":"7.64E-28"},"down","LOC107054271","-","-","-","-"]
["ST14",65.211304,31.636894,-1.043514101,{"v":7.22e-158,"d":"7.22E-158"},{"v":6.64e-157,"d":"6.64E-157"},"down","ST14","-","GO:0001843;GO:0004252;GO:0005576;GO:0006508;GO:0008233;GO:0008236;GO:0016020;GO:0016021;GO:0016787;GO:0019897;GO:0030216","-","KOG3627-Trypsin[E]"]
["BORL4",32.677673,15.850735,-1.043755512,{"v":5.08e-39,"d":"5.08E-39"},{"v":2.02e-38,"d":"2.02E-38"},"down","BORL4","-","-","-","-"]
["CD276",41.017437,19.891499,-1.044085347,{"v":1.61e-72,"d":"1.61E-72"},{"v":8.88e-72,"d":"8.88E-72"},"down","CD276","CD276 molecule","GO:0005102;GO:0009897;GO:0016020;GO:0016021;GO:0030501;GO:0042102;GO:0042110;GO:0042130;GO:0042802;GO:0045077;GO:0045078;GO:0045085;GO:0045669;GO:0050728;GO:0050776;GO:1900042","K06746-ko04514 Cell adhesion molecules (CAMs)","-"]
["RCOR3",20.977358,10.172044,-1.044223381,{"v":7.48e-76,"d":"7.48E-76"},{"v":4.22e-75,"d":"4.22E-75"},"down","RCOR3","REST corepressor 3","GO:0000122;GO:0003677;GO:0003700;GO:0003714;GO:0005634;GO:0005667;GO:0008134;GO:0017053;GO:0044212;GO:0000122;GO:0003677;GO:0003700;GO:0003714;GO:0005634;GO:0005667;GO:0006351;GO:0006355;GO:0008134;GO:0017053;GO:0044212","-","KOG1194-Predicted DNA-binding protein, contains Myb-like, SANT and ELM2 domains[K]"]
["RIPK2",26.01771,12.613497,-1.044525678,{"v":8.7e-73,"d":"8.70E-73"},{"v":4.8e-72,"d":"4.80E-72"},"down","RIPK2","receptor interacting serine/threonine kinase 2","GO:0000166;GO:0001961;GO:0002250;GO:0002376;GO:0002827;GO:0004672;GO:0004674;GO:0005102;GO:0005524;GO:0005737;GO:0005829;GO:0005856;GO:0006468;GO:0007249;GO:0010800;GO:0010942;GO:0016301;GO:0016310;GO:0016740;GO:0030274;GO:0031398;GO:0031663;GO:0031982;GO:0032092;GO:0032722;GO:0032729;GO:0032743;GO:0032755;GO:0032760;GO:0032874;GO:0032991;GO:0033091;GO:0033138;GO:0034134;GO:0034142;GO:0042098;GO:0042802;GO:0042803;GO:0042981;GO:0043065;GO:0043123;GO:0043330;GO:0045087;GO:0045627;GO:0046330;GO:0046641;GO:0050700;GO:0050718;GO:0050731;GO:0050830;GO:0050852;GO:0051092;GO:0070374;GO:0070427;GO:0070431;GO:0070555;GO:0070671;GO:0070673;GO:0071222;GO:0071223;GO:0071224;GO:0071225;GO:0089720;GO:0097202;GO:1904417","K08846-ko04621 NOD-like receptor signaling pathway;ko04722 Neurotrophin signaling pathway;ko05131 Shigellosis;ko05152 Tuberculosis","KOG0192-Tyrosine kinase specific for activated (GTP-bound) p21cdc42Hs[T]"]
["WDR47",30.86783,14.940071,-1.046917061,{"v":1.61e-114,"d":"1.61E-114"},{"v":1.19e-113,"d":"1.19E-113"},"down","WDR47","-","-","-","KOG0641-WD40 repeat protein[R]"]
["MUC13",165.281021,79.96196,-1.047535331,0,0,"down","MUC13","-","-","-","-"]
["LPAR2",99.571198,48.164837,-1.047748205,{"v":1.83e-122,"d":"1.83E-122"},{"v":1.41e-121,"d":"1.41E-121"},"down","LPAR2","lysophosphatidic acid receptor 2","GO:0004930;GO:0007165;GO:0007186;GO:0009986;GO:0016020;GO:0016021;GO:0030139;GO:0070915","K04291-ko04015 Rap1 signaling pathway;ko04072 Phospholipase D signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04080 Neuroactive ligand-receptor interaction;ko05200 Pathways in cancer","KOG4220-Muscarinic acetylcholine receptor[T]"]
["NEURL1B",14.008563,6.774724,-1.048074894,{"v":2.33e-58,"d":"2.33E-58"},{"v":1.14e-57,"d":"1.14E-57"},"down","NEURL1B","-","-","-","KOG4625-Notch signaling protein Neuralized, Nuez domain[T]"]
["BLNK",14.986733,7.24125,-1.049375255,{"v":3.32e-32,"d":"3.32E-32"},{"v":1.2e-31,"d":"1.20E-31"},"down","BLNK","B-cell linker","GO:0005068;GO:0005070;GO:0005515;GO:0005737;GO:0005829;GO:0005886;GO:0006955;GO:0007169;GO:0007202;GO:0009967;GO:0016020;GO:0030183;GO:0035556;GO:0036464;GO:0042113;GO:0051726","-","-"]
["TRIQK",13.280208,6.416544,-1.049409378,{"v":3.68e-38,"d":"3.68E-38"},{"v":1.44e-37,"d":"1.44E-37"},"down","TRIQK","-","-","-","-"]
["TALDO1",446.245575,215.587204,-1.049566313,0,0,"down","TALDO1","transaldolase 1","GO:0003824;GO:0004801;GO:0005634;GO:0005654;GO:0005737;GO:0005829;GO:0005975;GO:0006098;GO:0016740","K00616-ko01200 Carbon metabolism;ko01230 Biosynthesis of amino acids;ko00030 Pentose phosphate pathway","KOG2772-Transaldolase[G]"]
["GALNT12",50.569061,24.405188,-1.051067125,{"v":1.01e-156,"d":"1.01E-156"},{"v":9.24e-156,"d":"9.24E-156"},"down","GALNT12","-","GO:0000139;GO:0005794;GO:0006486;GO:0016020;GO:0016021;GO:0016740;GO:0016757;GO:0030246","K00710-ko00512 Mucin type O-glycan biosynthesis","KOG3736-Polypeptide N-acetylgalactosaminyltransferase[O]"]
["MYO1C",162.510696,78.398888,-1.051629579,0,0,"down","MYO1C","myosin IC","GO:0000166;GO:0003774;GO:0003779;GO:0005102;GO:0005524;GO:0005737;GO:0005886;GO:0005902;GO:0005903;GO:0006605;GO:0006612;GO:0008022;GO:0009925;GO:0016020;GO:0016328;GO:0016459;GO:0016604;GO:0017160;GO:0030050;GO:0030335;GO:0030659;GO:0031941;GO:0032420;GO:0038089;GO:0045121;GO:0045335;GO:0071346;GO:0090314;GO:1900078;GO:1900748;GO:2000810;GO:0000166;GO:0001726;GO:0003774;GO:0003779;GO:0005524;GO:0005737;GO:0005886;GO:0016020;GO:0016459;GO:0031410;GO:0042995;GO:0060171","-","KOG0164-Myosin class I heavy chain[Z]"]
["XRN1",8.438422,4.065773,-1.053443569,{"v":7.69e-38,"d":"7.69E-38"},{"v":3e-37,"d":"3.00E-37"},"down","XRN1","-","GO:0000956;GO:0003676;GO:0004527;GO:0004534;GO:0005634;GO:0005829;GO:0005886;GO:0008409;GO:0016075;GO:0071028;GO:0071044;GO:0090305;GO:0090503","K12618-ko03008 Ribosome biogenesis in eukaryotes;ko03018 RNA degradation","KOG2045-5'-3' exonuclease XRN1/KEM1/SEP1 involved in DNA strand exchange and mRNA turnover[LD]"]
["TRERF1",12.639839,6.087682,-1.054013183,{"v":7.43e-115,"d":"7.43E-115"},{"v":5.49e-114,"d":"5.49E-114"},"down","TRERF1","-","GO:0000118;GO:0003676;GO:0003677;GO:0003700;GO:0005634;GO:0005654;GO:0005667;GO:0005730;GO:0005829;GO:0006357;GO:0008134;GO:0044212","-","KOG4167-Predicted DNA-binding protein, contains SANT and ELM2 domains[K]"]
["GCOM1",34.557686,16.643614,-1.054037882,{"v":7.7e-201,"d":"7.70E-201"},{"v":8.52e-200,"d":"8.52E-200"},"down","GCOM1","-","GO:0005622;GO:0035556","-","-"]
["EFNB2",14.566583,7.014103,-1.054331971,{"v":5.55e-14,"d":"5.55E-14"},{"v":1.39e-13,"d":"1.39E-13"},"down","EFNB2","ephrin B2","GO:0001945;GO:0005102;GO:0005886;GO:0007411;GO:0009887;GO:0010839;GO:0016020;GO:0016021;GO:0016477;GO:0031295;GO:0046875;GO:0048013;GO:0048514;GO:0048845;GO:0072178;GO:0098685;GO:0098978;GO:0099061;GO:0099072;GO:0099149;GO:1903849;GO:2000727","-","KOG3858-Ephrin, ligand for Eph receptor tyrosine kinase[T]"]
["TUBA1C",156.376602,75.292816,-1.054440541,{"v":1.38e-198,"d":"1.38E-198"},{"v":1.5e-197,"d":"1.50E-197"},"down","TUBA1C","-","GO:0000166;GO:0003924;GO:0005200;GO:0005525;GO:0005737;GO:0005856;GO:0005874;GO:0007010;GO:0007017;GO:0015630","K07374-ko04145 Phagosome;ko04210 Apoptosis;ko04540 Gap junction;ko05130 Pathogenic Escherichia coli infection","KOG1376-Alpha tubulin[Z]"]
["BID",35.446171,17.055174,-1.055420318,{"v":8.21e-45,"d":"8.21E-45"},{"v":3.51e-44,"d":"3.51E-44"},"down","BID","BH3 interacting domain death agonist","GO:0001836;GO:0005737;GO:0005739;GO:0005829;GO:0006626;GO:0006919;GO:0008637;GO:0010918;GO:0016020;GO:0031625;GO:0032459;GO:0032461;GO:0032464;GO:0032592;GO:0042127;GO:0042775;GO:0042981;GO:0043065;GO:0046982;GO:0051260;GO:0090150;GO:0090200;GO:0097191;GO:0097284;GO:0097345;GO:1902108;GO:1902230;GO:2000045;GO:2000271;GO:2001235;GO:2001238;GO:2001244;GO:0005737;GO:0006915;GO:0042981;GO:0043065","K04726-ko04071 Sphingolipid signaling pathway;ko04210 Apoptosis;ko04215 Apoptosis - multiple species;ko04115 p53 signaling pathway;ko04650 Natural killer cell mediated cytotoxicity;ko05200 Pathways in cancer;ko05010 Alzheimer's disease;ko05014 Amyotrophic lateral sclerosis (ALS);ko05416 Viral myocarditis;ko04932 Non-alcoholic fatty liver disease (NAFLD);ko05152 Tuberculosis;ko01524 Platinum drug resistance","-"]
["ADAMTSL5",33.011536,15.877588,-1.055978501,{"v":3.26e-52,"d":"3.26E-52"},{"v":1.5e-51,"d":"1.50E-51"},"down","ADAMTSL5","-","GO:0005576;GO:0031012","-","KOG3538-Disintegrin metalloproteinases with thrombospondin repeats[O]"]
["RPS16",2638.542236,1268.733643,-1.056351855,0,0,"down","RPS16","-","GO:0000462;GO:0003723;GO:0003735;GO:0005840;GO:0006364;GO:0006412;GO:0022627;GO:0042274;GO:1990830","K02960-ko03010 Ribosome","KOG1753-40S ribosomal protein S16[J]"]
["ARF3",74.032829,35.579945,-1.057100879,{"v":1.32e-49,"d":"1.32E-49"},{"v":5.93e-49,"d":"5.93E-49"},"down","ARF3","-","GO:0000166;GO:0005525;GO:0005622","K07938-ko04144 Endocytosis","-"]
["DDHD2",11.321495,5.436786,-1.05823853,{"v":6.63e-54,"d":"6.63E-54"},{"v":3.1e-53,"d":"3.10E-53"},"down","DDHD2","-","GO:0004806;GO:0005815;GO:0005829;GO:0007626;GO:0008542;GO:0016020;GO:0019433;GO:0034389;GO:0046872;GO:0090141","-","KOG2308-Phosphatidic acid-preferring phospholipase A1, contains DDHD domain[IU]"]
["LOC100857473",5.090467,2.443432,-1.05888906,{"v":2.49e-10,"d":"2.49E-10"},{"v":5.52e-10,"d":"5.52E-10"},"down","LOC100857473","-","-","-","-"]
["FHL5",17.737787,8.509794,-1.059629914,{"v":3.51e-36,"d":"3.51E-36"},{"v":1.34e-35,"d":"1.34E-35"},"down","FHL5","four and a half LIM domains 5","GO:0003713;GO:0045944;GO:0046872","-","[KOG2272-Focal adhesion protein PINCH-1, contains LIM domains[TZ], KOG1703-Adaptor protein Enigma and related PDZ-LIM proteins[TZ]]"]
["TAF15",75.651993,36.283356,-1.060070187,{"v":5.12e-123,"d":"5.12E-123"},{"v":3.95e-122,"d":"3.95E-122"},"down","TAF15","-","GO:0003676;GO:0003723;GO:0005634;GO:0005654;GO:0005737;GO:0006355;GO:0046872","K14651-ko03022 Basal transcription factors;ko05202 Transcriptional misregulation in cancers","KOG1995-Conserved Zn-finger protein[R]"]
["TMEM123",103.49102,49.573914,-1.061852516,{"v":1.47e-228,"d":"1.47E-228"},{"v":1.8e-227,"d":"1.80E-227"},"down","TMEM123","transmembrane protein 123","GO:0016020;GO:0016021;GO:0009897;GO:0016020;GO:0016021;GO:0070267","-","-"]
["NAT8",7.408309,3.548049,-1.062118341,{"v":7.69e-07,"d":"7.69E-07"},{"v":1.46e-06,"d":"1.46E-06"},"down","NAT8","-","-","-","-"]
["MN1",41.93351,20.050341,-1.064476821,0,0,"down","MN1","-","GO:0001957;GO:0006355","-","-"]
["ELMO3",12.3823,5.92023,-1.064554188,{"v":2.93e-38,"d":"2.93E-38"},{"v":1.15e-37,"d":"1.15E-37"},"down","ELMO3","engulfment and cell motility 3","GO:0016477","-","KOG2999-Regulator of Rac1, required for phagocytosis and cell migration[T]"]
["GEM",52.362461,25.032227,-1.064746258,{"v":4.4e-61,"d":"4.40E-61"},{"v":2.2e-60,"d":"2.20E-60"},"down","GEM","GTP binding protein overexpressed in skeletal muscle","GO:0000166;GO:0000278;GO:0000287;GO:0003924;GO:0005525;GO:0005634;GO:0007165;GO:0009898;GO:0016020;GO:0019003;GO:0030496;GO:0051233;GO:0051276;GO:0051310;GO:0072686;GO:1901842","-","KOG0395-Ras-related GTPase[R]"]
["STAM2",32.171516,15.37653,-1.065053952,{"v":1e-39,"d":"1.00E-39"},{"v":4.03e-39,"d":"4.03E-39"},"down","STAM2","signal transducing adaptor molecule 2","GO:0005737;GO:0005768;GO:0006886;GO:0007165;GO:0015031;GO:0016020;GO:0017124;GO:0030139;GO:0031901;GO:0005622;GO:0005654;GO:0005737;GO:0005829;GO:0006886;GO:0043231","K04705-ko04630 Jak-STAT signaling pathway;ko04144 Endocytosis","KOG2199-Signal transducing adaptor protein STAM/STAM2[T]"]
["SORBS1",107.778069,51.465511,-1.066385788,0,0,"down","SORBS1","-","-","K06086-ko04520 Adherens junction;ko04910 Insulin signaling pathway;ko03320 PPAR signaling pathway","KOG4225-Sorbin and SH3 domain-containing protein[T]"]
["PAM",72.354065,34.514866,-1.067856189,{"v":2.89e-225,"d":"2.89E-225"},{"v":3.49e-224,"d":"3.49E-224"},"down","PAM","-","GO:0001519;GO:0003824;GO:0004497;GO:0004504;GO:0004598;GO:0005507;GO:0006518;GO:0008270;GO:0016020;GO:0016021;GO:0016715;GO:0055114","-","KOG3567-Peptidylglycine alpha-amidating monooxygenase[O]"]
["SLC6A9",23.366858,11.133103,-1.069608002,{"v":3.52e-55,"d":"3.52E-55"},{"v":1.67e-54,"d":"1.67E-54"},"down","SLC6A9","solute carrier family 6 member 9","GO:0003333;GO:0005215;GO:0005283;GO:0005328;GO:0005886;GO:0005887;GO:0006836;GO:0015187;GO:0015293;GO:0015816;GO:0016020;GO:0016021;GO:0055085;GO:0061537;GO:0098793;GO:1903825","-","KOG3660-Sodium-neurotransmitter symporter[T]"]
["SRPX",66.470589,31.64872,-1.070568985,{"v":3.12e-106,"d":"3.12E-106"},{"v":2.17e-105,"d":"2.17E-105"},"down","SRPX","-","GO:0001845;GO:0005776;GO:0005783;GO:0006914;GO:0034976;GO:0060244;GO:2001241","-","-"]
["TJP3",44.340904,21.110291,-1.070691717,{"v":1.81e-148,"d":"1.81E-148"},{"v":1.6e-147,"d":"1.60E-147"},"down","TJP3","-","GO:0005634;GO:0005923","K06097-ko04530 Tight junction","KOG3580-Tight junction proteins[T]"]
["TSPAN5",25.041817,11.910312,-1.07212804,{"v":8.24e-145,"d":"8.24E-145"},{"v":7.15e-144,"d":"7.15E-144"},"down","TSPAN5","-","GO:0005886;GO:0005887;GO:0007166;GO:0016020;GO:0016021;GO:0019899;GO:0045747;GO:0051604;GO:0072659","-","KOG3882-Tetraspanin family integral membrane protein[R]"]
["PROSER2",33.150223,15.758427,-1.072895043,{"v":1.1e-127,"d":"1.10E-127"},{"v":8.72e-127,"d":"8.72E-127"},"down","PROSER2","-","-","-","-"]
["PHACTR2",51.26033,24.34144,-1.074428248,{"v":9.04e-308,"d":"9.04E-308"},{"v":1.4e-306,"d":"1.40E-306"},"down","PHACTR2","-","GO:0003779;GO:0004864;GO:0032515","-","KOG4339-RPEL repeat-containing protein[R]"]
["SBF1",45.799644,21.745005,-1.074652344,{"v":3.03e-284,"d":"3.03E-284"},{"v":4.37e-283,"d":"4.37E-283"},"down","SBF1","-","GO:0019208;GO:0043087","-","KOG1090-Predicted dual-specificity phosphatase[R]"]
["GNAI3",201.536453,95.670113,-1.074900603,{"v":1.17e-169,"d":"1.17E-169"},{"v":1.14e-168,"d":"1.14E-168"},"down","GNAI3","G protein subunit alpha i3","GO:0000139;GO:0000166;GO:0003924;GO:0005525;GO:0005634;GO:0005730;GO:0005737;GO:0005789;GO:0005794;GO:0005813;GO:0005886;GO:0007165;GO:0007186;GO:0007188;GO:0007193;GO:0007212;GO:0016239;GO:0019001;GO:0019003;GO:0030496;GO:0031683;GO:0046039;GO:0051301","K04630-ko04015 Rap1 signaling pathway;ko04071 Sphingolipid signaling pathway;ko04024 cAMP signaling pathway;ko04022 cGMP - PKG signaling pathway;ko04530 Tight junction;ko04540 Gap junction;ko04611 Platelet activation;ko04670 Leukocyte transendothelial migration;ko04062 Chemokine signaling pathway;ko04923 Regulation of lipolysis in adipocyte;ko04915 Estrogen signaling pathway;ko04914 Progesterone-mediated oocyte maturation;ko04921 Oxytocin signaling pathway;ko04916 Melanogenesis;ko04924 Renin secretion;ko04261 Adrenergic signaling in cardiomyocytes;ko04971 Gastric acid secretion;ko04724 Glutamatergic synapse;ko04727 GABAergic synapse;ko04725 Cholinergic synapse;ko04728 Dopaminergic synapse;ko04726 Serotonergic synapse;ko04730 Long-term depression;ko04723 Retrograde endocannabinoid signaling;ko04360 Axon guidance;ko04713 Circadian entrainment;ko05200 Pathways in cancer;ko05012 Parkinson's disease;ko05030 Cocaine addiction;ko05032 Morphine addiction;ko05034 Alcoholism;ko05133 Pertussis;ko05145 Toxoplasmosis;ko05142 Chagas disease (American trypanosomiasis)","KOG0082-G-protein alpha subunit (small G protein superfamily)[DT]"]
["ASAP1",8.6872,4.120006,-1.076244814,{"v":3.6e-51,"d":"3.60E-51"},{"v":1.64e-50,"d":"1.64E-50"},"down","ASAP1","-","GO:0001786;GO:0002102;GO:0005096;GO:0005546;GO:0005547;GO:0005829;GO:0005886;GO:0017124;GO:0031253;GO:0032266;GO:0042277;GO:0043197;GO:0043547;GO:0046872;GO:0060271;GO:0061000;GO:0071803;GO:0098772;GO:1903527","K12488-ko04144 Endocytosis;ko04666 Fc gamma R-mediated phagocytosis","KOG0521-Putative GTPase activating proteins (GAPs)[T]"]
["HPGD",209.562485,99.289085,-1.077673441,0,0,"down","HPGD","hydroxyprostaglandin dehydrogenase 15-(NAD)","GO:0003824;GO:0004957;GO:0005654;GO:0005829;GO:0006693;GO:0007179;GO:0007186;GO:0007567;GO:0016323;GO:0016404;GO:0016491;GO:0045786;GO:0051287;GO:0055114;GO:0070403;GO:0097070","-","KOG4169-15-hydroxyprostaglandin dehydrogenase and related dehydrogenases[IR]"]
["VPS26B",36.606937,17.312363,-1.08031441,{"v":2.17e-139,"d":"2.17E-139"},{"v":1.82e-138,"d":"1.82E-138"},"down","VPS26B","-","GO:0005768;GO:0005769;GO:0005770;GO:0005829;GO:0006886;GO:0008565;GO:0030904;GO:0042147;GO:0045335;GO:0071346","K18466-ko04144 Endocytosis","KOG3063-Membrane coat complex Retromer, subunit VPS26[U]"]
["GMNN",39.366074,18.615612,-1.080439792,{"v":8.22e-44,"d":"8.22E-44"},{"v":3.47e-43,"d":"3.47E-43"},"down","GMNN","geminin, DNA replication inhibitor","GO:0003682;GO:0003714;GO:0005634;GO:0005737;GO:0005829;GO:0006275;GO:0008156;GO:0009887;GO:0010629;GO:0035563;GO:0042826;GO:0045786;GO:0045892;GO:0065003;GO:0070491;GO:0071163;GO:1902596;GO:2000104","-","-"]
["SNAI2",52.008606,24.585398,-1.080948659,{"v":4.17e-101,"d":"4.17E-101"},{"v":2.81e-100,"d":"2.81E-100"},"down","SNAI2","-","GO:0003676;GO:0008134;GO:0051219;GO:0060317","K05706-ko04390 Hippo signaling pathway;ko04520 Adherens junction","-"]
["IGSF5",12.659701,5.98353,-1.081174569,{"v":3.94e-28,"d":"3.94E-28"},{"v":1.33e-27,"d":"1.33E-27"},"down","IGSF5","-","-","K06786-ko04530 Tight junction;ko05120 Epithelial cell signaling in Helicobacter pylori infection","KOG4222-Axon guidance receptor Dscam[T]"]
["MPST",57.038761,26.94385,-1.081986632,{"v":1.08e-97,"d":"1.08E-97"},{"v":7.15e-97,"d":"7.15E-97"},"down","MPST","mercaptopyruvate sulfurtransferase","GO:0004792;GO:0016740;GO:0016784;GO:0043005;GO:0070814","K01011-ko00920 Sulfur metabolism;ko00270 Cysteine and methionine metabolism;ko04122 Sulfur relay system","KOG1529-Mercaptopyruvate sulfurtransferase/thiosulfate sulfurtransferase[V]"]
["NOTCH1",26.659544,12.588761,-1.082515806,{"v":1.69e-218,"d":"1.69E-218"},{"v":2e-217,"d":"2.00E-217"},"down","NOTCH1","notch 1","GO:0000122;GO:0000978;GO:0001190;GO:0001708;GO:0001837;GO:0001889;GO:0001947;GO:0002040;GO:0002193;GO:0002437;GO:0003151;GO:0003157;GO:0003160;GO:0003162;GO:0003169;GO:0003180;GO:0003181;GO:0003182;GO:0003184;GO:0003192;GO:0003197;GO:0003198;GO:0003203;GO:0003207;GO:0003208;GO:0003209;GO:0003213;GO:0003214;GO:0003219;GO:0003222;GO:0003241;GO:0003252;GO:0003256;GO:0003270;GO:0003273;GO:0003332;GO:0003344;GO:0003682;GO:0003700;GO:0004857;GO:0005112;GO:0005509;GO:0005634;GO:0005737;GO:0005783;GO:0005886;GO:0005912;GO:0006355;GO:0006357;GO:0006366;GO:0006959;GO:0007050;GO:0007219;GO:0007221;GO:0007275;GO:0007368;GO:0007386;GO:0007409;GO:0007440;GO:0007492;GO:0007507;GO:0008284;GO:0008285;GO:0008544;GO:0008593;GO:0009912;GO:0009986;GO:0010001;GO:0010468;GO:0010614;GO:0010628;GO:0010629;GO:0010718;GO:0010812;GO:0010832;GO:0014031;GO:0014807;GO:0016020;GO:0016021;GO:0016324;GO:0019899;GO:0021915;GO:0030154;GO:0030182;GO:0030216;GO:0030279;GO:0030324;GO:0030326;GO:0030334;GO:0030335;GO:0030513;GO:0030514;GO:0030900;GO:0031410;GO:0031490;GO:0032495;GO:0035116;GO:0035148;GO:0035914;GO:0035924;GO:0038023;GO:0042127;GO:0043065;GO:0043086;GO:0043235;GO:0043565;GO:0045070;GO:0045165;GO:0045596;GO:0045607;GO:0045608;GO:0045618;GO:0045662;GO:0045665;GO:0045668;GO:0045747;GO:0045892;GO:0045893;GO:0045944;GO:0045955;GO:0045967;GO:0046427;GO:0046533;GO:0046579;GO:0046872;GO:0046982;GO:0048103;GO:0048663;GO:0048711;GO:0048715;GO:0048754;GO:0048845;GO:0048873;GO:0050678;GO:0050679;GO:0050767;GO:0050768;GO:0050793;GO:0055008;GO:0060038;GO:0060045;GO:0060253;GO:0060317;GO:0060411;GO:0060412;GO:0060528;GO:0060548;GO:0060740;GO:0060768;GO:0060842;GO:0060843;GO:0060948;GO:0060956;GO:0060979;GO:0060982;GO:0061314;GO:0061384;GO:0061419;GO:0070168;GO:0070374;GO:0070986;GO:0071372;GO:0071944;GO:0072017;GO:0072044;GO:0072144;GO:0072602;GO:0090051;GO:0090090;GO:0097150;GO:0120163;GO:1901201;GO:1902263;GO:1902339;GO:1903849;GO:2000737;GO:2000811;GO:2000974;GO:2001027","K02599-ko04330 Notch signaling pathway;ko04919 Thyroid hormone signaling pathway;ko04320 Dorso-ventral axis formation;ko05206 MicroRNAs in cancer;ko05224 Breast cancer;ko01522 Endocrine resistance","KOG1217-Fibrillins and related proteins containing Ca2+-binding EGF-like domains[T]"]
["G6PD",127.074646,59.982819,-1.083054981,{"v":8.69e-75,"d":"8.69E-75"},{"v":4.86e-74,"d":"4.86E-74"},"down","G6PD","-","-","-","-"]
["LOC112530909",48.8209,23.044605,-1.083069852,{"v":8.77e-150,"d":"8.77E-150"},{"v":7.78e-149,"d":"7.78E-149"},"down","LOC112530909","-","-","-","-"]
["PITPNC1L",37.497025,17.697668,-1.083216867,{"v":1.09e-58,"d":"1.09E-58"},{"v":5.37e-58,"d":"5.37E-58"},"down","PITPNC1L","-","GO:0005548;GO:0005622;GO:0015914","-","-"]
["SYNPR",9.029441,4.260604,-1.083578708,{"v":5.51e-24,"d":"5.51E-24"},{"v":1.73e-23,"d":"1.73E-23"},"down","SYNPR","synaptoporin","GO:0008021;GO:0016020;GO:0016021;GO:0030285","-","-"]
["MAOB",10.157199,4.789359,-1.084598126,{"v":3.17e-57,"d":"3.17E-57"},{"v":1.54e-56,"d":"1.54E-56"},"down","MAOB","-","GO:0016020;GO:0016021;GO:0016491;GO:0055114","K00274-ko00260 Glycine, serine and threonine metabolism;ko00330 Arginine and proline metabolism;ko00340 Histidine metabolism;ko00350 Tyrosine metabolism;ko00360 Phenylalanine metabolism;ko00380 Tryptophan metabolism;ko00950 Isoquinoline alkaloid biosynthesis;ko00982 Drug metabolism - cytochrome P450;ko04728 Dopaminergic synapse;ko04726 Serotonergic synapse;ko05030 Cocaine addiction;ko05031 Amphetamine addiction;ko05034 Alcoholism","-"]
["SEMA3A",13.029616,6.13754,-1.086062139,{"v":8.34e-40,"d":"8.34E-40"},{"v":3.35e-39,"d":"3.35E-39"},"down","SEMA3A","semaphorin 3A","GO:0005576;GO:0005615;GO:0007275;GO:0007399;GO:0008045;GO:0030154;GO:0030424;GO:0038191;GO:0044297;GO:0050807;GO:0050919;GO:0097156;GO:0098978;GO:1990535;GO:2000009;GO:2001224;GO:0001764;GO:0002027;GO:0005615;GO:0007411;GO:0007413;GO:0008045;GO:0010633;GO:0010977;GO:0021612;GO:0021637;GO:0021675;GO:0021772;GO:0021785;GO:0021828;GO:0030215;GO:0030517;GO:0036486;GO:0038191;GO:0044297;GO:0045499;GO:0048813;GO:0048841;GO:0048843;GO:0048846;GO:0050919;GO:0060385;GO:0060666;GO:0061549;GO:0061551;GO:0071526;GO:0097156;GO:0097490;GO:0097491;GO:0150020;GO:1901166;GO:1902285;GO:1902287;GO:1903045;GO:1903375;GO:1990535;GO:2000009;GO:2000020;GO:2001224","-","KOG3611-Semaphorins[T]"]
["CAD",15.702469,7.393,-1.086759603,{"v":6.1e-100,"d":"6.10E-100"},{"v":4.09e-99,"d":"4.09E-99"},"down","CAD","-","GO:0003677;GO:0004518;GO:0005622;GO:0005634;GO:0005730;GO:0005737;GO:0006309;GO:0006915;GO:0016787;GO:0000050;GO:0000166;GO:0004070;GO:0004087;GO:0004088;GO:0004151;GO:0005524;GO:0005634;GO:0005654;GO:0005737;GO:0005829;GO:0006207;GO:0006526;GO:0006541;GO:0006807;GO:0008270;GO:0016363;GO:0016787;GO:0016810;GO:0016812;GO:0019899;GO:0042802;GO:0046872;GO:0003779;GO:0005516;GO:0005623;GO:0005737;GO:0005856;GO:0006936;GO:0017022;GO:0030016;GO:0044548;GO:0045159;GO:1903611","K11540-ko00240 Pyrimidine metabolism;ko00250 Alanine, aspartate and glutamate metabolism","-"]
["PAK4",30.80036,14.495831,-1.087309173,{"v":2.71e-71,"d":"2.71E-71"},{"v":1.48e-70,"d":"1.48E-70"},"down","PAK4","-","GO:0000166;GO:0004672;GO:0004674;GO:0005524;GO:0006468;GO:0016301;GO:0016310;GO:0016740;GO:0045766;GO:0060996;GO:0071407;GO:2000352","K05734-ko04014 Ras signaling pathway;ko04012 ErbB signaling pathway;ko04810 Regulation of actin cytoskeleton;ko04510 Focal adhesion;ko04660 T cell receptor signaling pathway;ko04360 Axon guidance;ko05206 MicroRNAs in cancer;ko05211 Renal cell carcinoma","KOG0578-p21-activated serine/threonine protein kinase[T]"]
["SAMD13",7.477088,3.518502,-1.08751518,{"v":2.85e-07,"d":"2.85E-07"},{"v":5.53e-07,"d":"5.53E-07"},"down","SAMD13","sterile alpha motif domain containing 13","-","-","-"]
["NEMP2",16.434965,7.731655,-1.087919216,{"v":1.01e-54,"d":"1.01E-54"},{"v":4.77e-54,"d":"4.77E-54"},"down","NEMP2","nuclear envelope integral membrane protein 2","GO:0016020;GO:0016021;GO:0005634;GO:0005635;GO:0005637;GO:0016020;GO:0016021","-","KOG3817-Uncharacterized conserved protein[S]"]
["ANKRD50",28.026596,13.171478,-1.089379288,{"v":6.51e-212,"d":"6.51E-212"},{"v":7.52e-211,"d":"7.52E-211"},"down","ANKRD50","-","GO:0005622;GO:1990126","-","KOG4177-Ankyrin[M]"]
["UNKL",21.137363,9.927402,-1.090307285,{"v":2.65e-79,"d":"2.65E-79"},{"v":1.54e-78,"d":"1.54E-78"},"down","UNKL","-","GO:0046872","-","-"]
["ARL4C",22.58181,10.602656,-1.090735417,{"v":1.76e-75,"d":"1.76E-75"},{"v":9.91e-75,"d":"9.91E-75"},"down","ARL4C","-","GO:0000166;GO:0005525;GO:0005622;GO:0005737;GO:0005829;GO:0005886;GO:0032456;GO:0043014","-","KOG0070-GTP-binding ADP-ribosylation factor Arf1[U]"]
["RFNG",37.183952,17.457899,-1.090800166,{"v":4.63e-127,"d":"4.63E-127"},{"v":3.66e-126,"d":"3.66E-126"},"down","RFNG","RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase","GO:0000139;GO:0005794;GO:0007275;GO:0007389;GO:0007399;GO:0008593;GO:0016020;GO:0016021;GO:0016740;GO:0016757;GO:0030154;GO:0030173;GO:0032092;GO:0033829;GO:0036066;GO:0045747;GO:0046872","K05948-ko00514 Other types of O-glycan biosynthesis;ko04330 Notch signaling pathway","-"]
["GSKIP",20.472183,9.610944,-1.090914902,{"v":2.73e-43,"d":"2.73E-43"},{"v":1.14e-42,"d":"1.14E-42"},"down","GSKIP","GSK3B interacting protein","GO:0004860;GO:0005634;GO:0005737;GO:0006469;GO:0008631;GO:0019901;GO:0030111;GO:0034237;GO:0051018;GO:0060828;GO:0090263","-","KOG3965-Uncharacterized conserved protein[S]"]
["MTMR2",36.661556,17.20845,-1.091150862,{"v":7.93e-131,"d":"7.93E-131"},{"v":6.4e-130,"d":"6.40E-130"},"down","MTMR2","myotubularin related protein 2","GO:0004725;GO:0016311;GO:0016791;GO:0035335;GO:0004438;GO:0004725;GO:0005634;GO:0005737;GO:0005768;GO:0005774;GO:0005829;GO:0006629;GO:0016020;GO:0016311;GO:0016787;GO:0016791;GO:0031642;GO:0031901;GO:0032288;GO:0035335;GO:0042803;GO:0043231;GO:0046488;GO:0046855;GO:0046856;GO:0048666;GO:0051262;GO:0052629;GO:0052866;GO:0060304","K18081-ko00562 Inositol phosphate metabolism;ko04070 Phosphatidylinositol signaling system","KOG4471-Phosphatidylinositol 3-phosphate 3-phosphatase myotubularin MTM1[IU]"]
["TMEM79",44.138023,20.712355,-1.091530413,{"v":7.92e-59,"d":"7.92E-59"},{"v":3.9e-58,"d":"3.90E-58"},"down","TMEM79","-","GO:0002070;GO:0005737;GO:0005765;GO:0016020;GO:0016021;GO:0032588;GO:0042335;GO:0042802;GO:0045055;GO:0045684;GO:0061436;GO:0070268","-","-"]
["PFKFB2",19.869291,9.32164,-1.091884691,{"v":2.36e-92,"d":"2.36E-92"},{"v":1.5e-91,"d":"1.50E-91"},"down","PFKFB2","-","GO:0003824;GO:0003873;GO:0005524;GO:0005634;GO:0005654;GO:0006000;GO:0006003;GO:0006096;GO:0008152;GO:0019901;GO:0046835","K19029-ko00051 Fructose and mannose metabolism;ko04152 AMPK signaling pathway;ko04919 Thyroid hormone signaling pathway","KOG0234-Fructose-6-phosphate 2-kinase/fructose-2,6-biphosphatase[G]"]
["MMP13",9.143581,4.286377,-1.093000549,{"v":7.07e-23,"d":"7.07E-23"},{"v":2.17e-22,"d":"2.17E-22"},"down","MMP13","matrix metallopeptidase 13","GO:0001958;GO:0003417;GO:0004222;GO:0005509;GO:0005518;GO:0005576;GO:0006508;GO:0008233;GO:0008237;GO:0008270;GO:0016787;GO:0022617;GO:0030282;GO:0030574;GO:0031012;GO:0044267;GO:0046872;GO:0051216;GO:0060349","-","KOG1565-Gelatinase A and related matrix metalloproteases[OW]"]
["NR2F1",22.239939,10.418313,-1.094031145,{"v":2.12e-74,"d":"2.12E-74"},{"v":1.19e-73,"d":"1.19E-73"},"down","NR2F1","-","GO:0003677;GO:0003700;GO:0003707;GO:0004879;GO:0005634;GO:0006351;GO:0006355;GO:0008270;GO:0030522;GO:0043401;GO:0043565;GO:0046872","-","KOG4215-Hepatocyte nuclear factor 4 and similar steroid hormone receptors[K]"]
["MIR1647",24.426952,11.442067,-1.094126158,0.001132893,0.001743215,"down","MIR1647","microRNA 1647","-","-","-"]
["PARD6B",21.440649,10.043137,-1.094138607,{"v":7.38e-34,"d":"7.38E-34"},{"v":2.73e-33,"d":"2.73E-33"},"down","PARD6B","par-6 family cell polarity regulator beta","GO:0005634;GO:0005829;GO:0005886;GO:0005923;GO:0005938;GO:0007043;GO:0007163;GO:0016324;GO:0045177;GO:0065003","K06093-ko04015 Rap1 signaling pathway;ko04390 Hippo signaling pathway;ko04391 Hippo signaling pathway -fly;ko04144 Endocytosis;ko04530 Tight junction;ko04360 Axon guidance","KOG3606-Cell polarity protein PAR6[T]"]
["NTN1",11.187713,5.238412,-1.094713713,{"v":2.96e-23,"d":"2.96E-23"},{"v":9.15e-23,"d":"9.15E-23"},"down","NTN1","netrin 1","GO:0001764;GO:0005515;GO:0005576;GO:0005604;GO:0005622;GO:0005737;GO:0006930;GO:0007097;GO:0007265;GO:0007409;GO:0007411;GO:0008284;GO:0030334;GO:0030517;GO:0032488;GO:0033564;GO:0042472;GO:0045773;GO:0051963;GO:0071944;GO:0098609;GO:2000147","-","-"]
["LOC112532889",7.97021,3.730267,-1.09533884,0.003388832,0.004979214,"down","LOC112532889","-","-","-","-"]
["ATXN7L2",12.793266,5.987181,-1.095435827,{"v":7.74e-32,"d":"7.74E-32"},{"v":2.78e-31,"d":"2.78E-31"},"down","ATXN7L2","-","-","-","-"]
["HOXA4",84.488411,39.513737,-1.09639917,{"v":3.6e-142,"d":"3.60E-142"},{"v":3.08e-141,"d":"3.08E-141"},"down","HOXA4","homeobox A4","GO:0003677;GO:0003700;GO:0005634;GO:0006351;GO:0006355;GO:0007275;GO:0016604;GO:0043565;GO:0003677;GO:0005634;GO:0006355;GO:0043565","-","KOG0489-Transcription factor zerknullt and related HOX domain proteins[R]"]
["ADAM33",21.561928,10.062156,-1.099546723,{"v":8.76e-77,"d":"8.76E-77"},{"v":4.97e-76,"d":"4.97E-76"},"down","ADAM33","ADAM metallopeptidase domain 33","GO:0004222;GO:0006508;GO:0008237;GO:0016020;GO:0016021","-","KOG3607-Meltrins, fertilins and related Zn-dependent metalloproteinases of the ADAMs family[O]"]
["RALGPS2",25.684696,11.962255,-1.102419621,{"v":2.66e-198,"d":"2.66E-198"},{"v":2.89e-197,"d":"2.89E-197"},"down","RALGPS2","Ral GEF with PH domain and SH3 binding motif 2","GO:0005085;GO:0005622;GO:0007264;GO:0032485","-","KOG3417-Ras1 guanine nucleotide exchange factor[T]"]
["MAPKBP1",16.331553,7.60248,-1.103119965,{"v":3.58e-87,"d":"3.58E-87"},{"v":2.2e-86,"d":"2.20E-86"},"down","MAPKBP1","-","-","-","KOG1408-WD40 repeat protein[S]"]
["SCARB2",79.077583,36.799911,-1.103566499,{"v":6.65e-152,"d":"6.65E-152"},{"v":5.96e-151,"d":"5.96E-151"},"down","SCARB2","-","GO:0001508;GO:0005044;GO:0005764;GO:0005765;GO:0006622;GO:0006898;GO:0016020;GO:0016021;GO:0019899;GO:0043202;GO:1905123","K12384-ko04142 Lysosome","KOG3776-Plasma membrane glycoprotein CD36 and related membrane receptors[T]"]
["PRPSAP1",67.212967,31.264124,-1.104231496,{"v":1.12e-140,"d":"1.12E-140"},{"v":9.48e-140,"d":"9.48E-140"},"down","PRPSAP1","-","GO:0000287;GO:0004749;GO:0009116;GO:0009165;GO:0042802","-","KOG1503-Phosphoribosylpyrophosphate synthetase-associated protein[EF]"]
["TCEA1",42.310764,19.680483,-1.104259109,{"v":3.22e-65,"d":"3.22E-65"},{"v":1.66e-64,"d":"1.66E-64"},"down","TCEA1","transcription elongation factor A1","GO:0003676;GO:0005634;GO:0005669;GO:0005730;GO:0006351;GO:0006355;GO:0008270;GO:0046872;GO:0003676;GO:0005634;GO:0006351;GO:0006355;GO:0008270;GO:0046872","-","KOG1105-Transcription elongation factor TFIIS/Cofactor of enhancer-binding protein Sp1[K]"]
["AACS",31.004711,14.410769,-1.105340118,{"v":7.21e-97,"d":"7.21E-97"},{"v":4.75e-96,"d":"4.75E-96"},"down","AACS","acetoacetyl-CoA synthetase","GO:0003824;GO:0006629;GO:0008152;GO:0030729;GO:0000166;GO:0003824;GO:0005524;GO:0005737;GO:0005829;GO:0006629;GO:0006631;GO:0008152;GO:0016874;GO:0030729","K01907-ko00650 Butanoate metabolism;ko00280 Valine, leucine and isoleucine degradation","KOG1175-Acyl-CoA synthetase[I]"]
["EMP2",349.907013,162.61438,-1.105516739,0,0,"down","EMP2","-","GO:0001765;GO:0001913;GO:0001952;GO:0001954;GO:0003093;GO:0005178;GO:0005737;GO:0005794;GO:0005829;GO:0005886;GO:0007015;GO:0007155;GO:0007160;GO:0008219;GO:0008284;GO:0009986;GO:0010594;GO:0016020;GO:0016021;GO:0016324;GO:0016477;GO:0019900;GO:0019901;GO:0031410;GO:0032060;GO:0032147;GO:0034394;GO:0043534;GO:0043549;GO:0045022;GO:0045121;GO:0045177;GO:0045765;GO:0070252;GO:0072659;GO:2001046;GO:2001212","-","-"]
["CLDND1",71.526222,33.234768,-1.105778958,{"v":2.74e-141,"d":"2.74E-141"},{"v":2.33e-140,"d":"2.33E-140"},"down","CLDND1","claudin domain containing 1","GO:0016020;GO:0016021;GO:0016020;GO:0016021;GO:0016324","-","-"]
["ARRDC1",47.022568,21.840511,-1.106346718,{"v":4.82e-126,"d":"4.82E-126"},{"v":3.79e-125,"d":"3.79E-125"},"down","ARRDC1","arrestin domain containing 1","GO:0005886;GO:0006511;GO:0006858;GO:0015031;GO:0016567;GO:0031410;GO:0031625;GO:0042802;GO:0045746;GO:0140112;GO:1903561;GO:1990756;GO:1990763","-","KOG3780-Thioredoxin binding protein TBP-2/VDUP1[R]"]
["CTSK",162.095673,75.275665,-1.106590127,{"v":3.64e-193,"d":"3.64E-193"},{"v":3.88e-192,"d":"3.88E-192"},"down","CTSK","cathepsin K","GO:0001968;GO:0004197;GO:0005518;GO:0005615;GO:0005654;GO:0005764;GO:0006508;GO:0008233;GO:0008234;GO:0016787;GO:0030574;GO:0043231;GO:0043394;GO:0051603","K01371-ko04142 Lysosome;ko04210 Apoptosis;ko04620 Toll-like receptor signaling pathway;ko04380 Osteoclast differentiation;ko05323 Rheumatoid arthritis","KOG1543-Cysteine proteinase Cathepsin L[O]"]
["SGSH",40.073334,18.606806,-1.106812116,{"v":2.55e-71,"d":"2.55E-71"},{"v":1.39e-70,"d":"1.39E-70"},"down","SGSH","-","GO:0003824;GO:0005764;GO:0006027;GO:0008152;GO:0008484;GO:0016250;GO:0030200","K01565-ko00531 Glycosaminoglycan degradation;ko04142 Lysosome","KOG3867-Sulfatase[R]"]
["RMDN1",26.962622,12.517641,-1.106998093,{"v":5.98e-30,"d":"5.98E-30"},{"v":2.09e-29,"d":"2.09E-29"},"down","RMDN1","regulator of microtubule dynamics 1","-","-","-"]
["CDK1",30.096664,13.963517,-1.107941224,{"v":3.98e-35,"d":"3.98E-35"},{"v":1.5e-34,"d":"1.50E-34"},"down","CDK1","cyclin dependent kinase 1","GO:0000086;GO:0000166;GO:0000226;GO:0000724;GO:0004672;GO:0004674;GO:0004693;GO:0005524;GO:0005634;GO:0005654;GO:0005737;GO:0005815;GO:0005856;GO:0006281;GO:0006468;GO:0007049;GO:0007346;GO:0008353;GO:0010468;GO:0016301;GO:0016310;GO:0016572;GO:0016740;GO:0030154;GO:0034605;GO:0051301;GO:0051445;GO:0072686;GO:0000086;GO:0000166;GO:0000307;GO:0003682;GO:0004672;GO:0004674;GO:0004693;GO:0005524;GO:0005634;GO:0005759;GO:0005813;GO:0005829;GO:0005876;GO:0006468;GO:0007095;GO:0008283;GO:0008353;GO:0010971;GO:0016301;GO:0016572;GO:0018105;GO:0018107;GO:0030332;GO:0030496;GO:0030544;GO:0030855;GO:0034501;GO:0034605;GO:0035173;GO:0043066;GO:0044772;GO:0072686;GO:0097125;GO:0097472;GO:1900182;GO:1905448","K02087-ko04110 Cell cycle;ko04114 Oocyte meiosis;ko04115 p53 signaling pathway;ko04540 Gap junction;ko04914 Progesterone-mediated oocyte maturation;ko05203 Viral carcinogenesis;ko05168 Herpes simplex infection;ko05169 Epstein-Barr virus infection","KOG0594-Protein kinase PCTAIRE and related kinases[R]"]
["KRT18",72.53019,33.649185,-1.108010066,{"v":5.1e-96,"d":"5.10E-96"},{"v":3.33e-95,"d":"3.33E-95"},"down","KRT18","-","GO:0005198;GO:0005737;GO:0005815;GO:0005829;GO:0005882;GO:0033209;GO:0034451;GO:0043000;GO:0043066;GO:0045095;GO:0045104;GO:0071944;GO:0097110;GO:0097191;GO:0097284","-","KOG0977-Nuclear envelope protein lamin, intermediate filament superfamily[DY]"]
["FAM214B",11.937397,5.529593,-1.110243084,{"v":3.54e-40,"d":"3.54E-40"},{"v":1.43e-39,"d":"1.43E-39"},"down","FAM214B","-","-","-","KOG2306-Uncharacterized conserved protein[S]"]
["ROCK1",78.514648,36.357883,-1.110693635,0,0,"down","ROCK1","Rho-associated, coiled-coil containing protein kinase 1","GO:0000166;GO:0001726;GO:0003383;GO:0004672;GO:0004674;GO:0005524;GO:0005856;GO:0005886;GO:0006468;GO:0007159;GO:0007249;GO:0007266;GO:0010494;GO:0010508;GO:0010613;GO:0010628;GO:0016301;GO:0016310;GO:0016525;GO:0016740;GO:0017048;GO:0017049;GO:0022614;GO:0030027;GO:0030036;GO:0030866;GO:0031175;GO:0032060;GO:0032091;GO:0032956;GO:0032970;GO:0035509;GO:0035556;GO:0043410;GO:0043524;GO:0045616;GO:0045664;GO:0046872;GO:0050900;GO:0050901;GO:0051451;GO:0051492;GO:0051493;GO:0051894;GO:0071559;GO:0072659;GO:0106003;GO:0110061;GO:0140058;GO:1900223;GO:1900242;GO:1902430;GO:1902992;GO:1903140;GO:1903347;GO:1905205;GO:1990776;GO:2000114","K04514-ko04350 TGF-beta signaling pathway;ko04071 Sphingolipid signaling pathway;ko04024 cAMP signaling pathway;ko04022 cGMP - PKG signaling pathway;ko04810 Regulation of actin cytoskeleton;ko04510 Focal adhesion;ko04611 Platelet activation;ko04670 Leukocyte transendothelial migration;ko04062 Chemokine signaling pathway;ko04921 Oxytocin signaling pathway;ko04270 Vascular smooth muscle contraction;ko04360 Axon guidance;ko05200 Pathways in cancer;ko05206 MicroRNAs in cancer;ko05205 Proteoglycans in cancer;ko05130 Pathogenic Escherichia coli infection;ko05132 Salmonella infection;ko05131 Shigellosis","KOG0612-Rho-associated, coiled-coil containing protein kinase[T]"]
["SIPA1L2",10.923367,5.056786,-1.111124988,{"v":1.35e-139,"d":"1.35E-139"},{"v":1.14e-138,"d":"1.14E-138"},"down","SIPA1L2","-","GO:0005096;GO:0043547;GO:0051056","-","KOG3686-Rap1-GTPase-activating protein (Rap1GAP)[T]"]
["LOC112530435",47.068939,21.783197,-1.111559627,{"v":1.64e-20,"d":"1.64E-20"},{"v":4.79e-20,"d":"4.79E-20"},"down","LOC112530435","-","-","-","-"]
["OSBPL8",49.924931,23.071796,-1.11363012,0,0,"down","OSBPL8","-","GO:0001786;GO:0005548;GO:0006869;GO:0010891;GO:0015485;GO:0015914;GO:0016020;GO:0016021;GO:0030336;GO:0031965;GO:0032148;GO:0045444;GO:0046628;GO:0051897;GO:0070273;GO:0090204;GO:2001275","-","KOG2210-Oxysterol-binding protein[T]"]
["FILIP1L",86.33503,39.897411,-1.113650913,0,0,"down","FILIP1L","-","-","-","-"]
["PIK3CG",16.098087,7.438532,-1.11379942,{"v":6.41e-157,"d":"6.41E-157"},{"v":5.86e-156,"d":"5.86E-156"},"down","PIK3CG","phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma","GO:0000166;GO:0001932;GO:0002250;GO:0005524;GO:0005737;GO:0005886;GO:0005944;GO:0006468;GO:0006954;GO:0007186;GO:0010818;GO:0014065;GO:0016020;GO:0016301;GO:0016303;GO:0016310;GO:0016740;GO:0030593;GO:0035005;GO:0036092;GO:0042802;GO:0043085;GO:0043406;GO:0045087;GO:0046854;GO:0046875;GO:0046934;GO:0048015;GO:0051897;GO:0070527;GO:0071320;GO:1903169;GO:2000270","-","KOG0904-Phosphatidylinositol 3-kinase catalytic subunit (p110)[T]"]
["BTC",35.111553,16.218174,-1.114334413,{"v":2.94e-31,"d":"2.94E-31"},{"v":1.05e-30,"d":"1.05E-30"},"down","BTC","betacellulin","GO:0001556;GO:0005154;GO:0005615;GO:0007173;GO:0008083;GO:0008284;GO:0010468;GO:0010469;GO:0010628;GO:0016020;GO:0016021;GO:0043066;GO:0043410;GO:0060014","K09783-ko04012 ErbB signaling pathway","-"]
["BTG1L",29.742599,13.732734,-1.114911845,{"v":1.89e-34,"d":"1.89E-34"},{"v":7.05e-34,"d":"7.05E-34"},"down","BTG1L","-","-","-","-"]
["CACNB4",8.555408,3.949213,-1.115271476,{"v":1.24e-25,"d":"1.24E-25"},{"v":4e-25,"d":"4.00E-25"},"down","CACNB4","calcium voltage-gated channel auxiliary subunit beta 4","GO:0005245;GO:0005891;GO:0006816;GO:0007214;GO:0007528;GO:0007628;GO:0014051;GO:0019227;GO:0035249;GO:0042391;GO:0046058;GO:0048536;GO:0048538;GO:0048541;GO:0048747;GO:0050852;GO:0050877;GO:0050908;GO:0070588;GO:0098978;GO:1990830;GO:2000300","K04865-ko04010 MAPK signaling pathway;ko04921 Oxytocin signaling pathway;ko04260 Cardiac muscle contraction;ko04261 Adrenergic signaling in cardiomyocytes;ko05410 Hypertrophic cardiomyopathy (HCM);ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC);ko05414 Dilated cardiomyopathy (DCM)","-"]
["LOC107054251",6.991386,3.225797,-1.115922837,{"v":1.93e-05,"d":"1.93E-05"},{"v":3.38e-05,"d":"3.38E-05"},"down","LOC107054251","-","-","-","-"]
["TRIM69",15.603298,7.183794,-1.119033112,{"v":1.86e-41,"d":"1.86E-41"},{"v":7.66e-41,"d":"7.66E-41"},"down","TRIM69","-","-","-","-"]
["MFSD10",26.960075,12.402372,-1.120208442,{"v":3.32e-54,"d":"3.32E-54"},{"v":1.56e-53,"d":"1.56E-53"},"down","MFSD10","-","GO:0005215;GO:0008493;GO:0008514;GO:0015904;GO:0016020;GO:0016021;GO:0030659;GO:0031526;GO:0043252;GO:0055085","-","-"]
["FZD4",90.266632,41.477047,-1.121879595,0,0,"down","FZD4","frizzled class receptor 4","GO:0001540;GO:0001553;GO:0001568;GO:0001570;GO:0004888;GO:0004930;GO:0005886;GO:0005911;GO:0007165;GO:0007166;GO:0007186;GO:0007223;GO:0007275;GO:0007605;GO:0009986;GO:0010812;GO:0016020;GO:0016021;GO:0016055;GO:0017147;GO:0019955;GO:0030165;GO:0030425;GO:0030947;GO:0031625;GO:0031987;GO:0034446;GO:0035426;GO:0035567;GO:0038023;GO:0042701;GO:0042803;GO:0042813;GO:0043507;GO:0044877;GO:0045202;GO:0045893;GO:0046982;GO:0051091;GO:0060070;GO:0061299;GO:0061301;GO:0061304;GO:0070062;GO:0098978;GO:0150012;GO:1990830","K02354-ko04310 Wnt signaling pathway;ko04390 Hippo signaling pathway;ko04150 mTOR signaling pathway;ko04550 Signaling pathways regulating pluripotency of stem cells;ko04916 Melanogenesis;ko05200 Pathways in cancer;ko05205 Proteoglycans in cancer;ko05217 Basal cell carcinoma;ko05224 Breast cancer;ko05166 HTLV-I infection","KOG3577-Smoothened and related G-protein-coupled receptors[T]"]
["RAP2C",53.928566,24.76725,-1.122615982,{"v":5.4e-57,"d":"5.40E-57"},{"v":2.62e-56,"d":"2.62E-56"},"down","RAP2C","RAP2C, member of RAS oncogene family","GO:0000166;GO:0003713;GO:0003924;GO:0005525;GO:0005737;GO:0005829;GO:0005886;GO:0005923;GO:0007165;GO:0016020;GO:0019003;GO:0030336;GO:0031954;GO:0032486;GO:0044291;GO:0055037;GO:0055038;GO:0061097;GO:0090557;GO:1903508","-","KOG0395-Ras-related GTPase[R]"]
["RPL22L1",429.026245,197.031357,-1.122640656,{"v":2.44e-210,"d":"2.44E-210"},{"v":2.8e-209,"d":"2.80E-209"},"down","RPL22L1","ribosomal protein L22 like 1","GO:0002181;GO:0003723;GO:0003735;GO:0005622;GO:0005840;GO:0006412;GO:0022625","K02891-ko03010 Ribosome","KOG3434-60S ribosomal protein L22[J]"]
["CLN6",91.834305,42.164932,-1.12298955,{"v":5.82e-99,"d":"5.82E-99"},{"v":3.88e-98,"d":"3.88E-98"},"down","CLN6","ceroid-lipofuscinosis, neuronal 6, late infantile, variant","GO:0001573;GO:0005783;GO:0005788;GO:0007040;GO:0007042;GO:0007601;GO:0008203;GO:0016020;GO:0016021;GO:0030203;GO:0031987;GO:0042803;GO:0044265;GO:0045862","-","-"]
["C2H6orf52",98.61776,45.266914,-1.123390527,{"v":2.94e-140,"d":"2.94E-140"},{"v":2.49e-139,"d":"2.49E-139"},"down","C2H6orf52","chromosome 2 C6orf52 homolog","GO:0003676;GO:0003723","-","KOG0148-Apoptosis-promoting RNA-binding protein TIA-1/TIAR (RRM superfamily)[AJ]"]
["UHRF1",7.64443,3.506795,-1.124255836,{"v":3.31e-30,"d":"3.31E-30"},{"v":1.16e-29,"d":"1.16E-29"},"down","UHRF1","-","GO:0000122;GO:0000790;GO:0000792;GO:0005634;GO:0005657;GO:0005720;GO:0010216;GO:0010390;GO:0016363;GO:0031493;GO:0035064;GO:0042802;GO:0044729;GO:0046872;GO:0051865;GO:0061630","-","KOG1245-Chromatin remodeling complex WSTF-ISWI, large subunit (contains heterochromatin localization, PHD and BROMO domains)[B]"]
["AGAP3",35.500481,16.281836,-1.12457518,{"v":2.02e-129,"d":"2.02E-129"},{"v":1.62e-128,"d":"1.62E-128"},"down","AGAP3","-","GO:0003924;GO:0005525;GO:0007165;GO:0016020","K12491-ko04144 Endocytosis","KOG0705-GTPase-activating protein Centaurin gamma (contains Ras-like GTPase, PH and ankyrin repeat domains)[T]"]
["C9ORF152",92.750648,42.523716,-1.125089687,{"v":1.15e-131,"d":"1.15E-131"},{"v":9.32e-131,"d":"9.32E-131"},"down","C9ORF152","chromosome 2 open reading frame, human C9orf152","-","-","-"]
["ARRDC4",66.636604,30.545948,-1.125333863,{"v":3e-268,"d":"3.00E-268"},{"v":4.16e-267,"d":"4.16E-267"},"down","ARRDC4","-","GO:0005768;GO:0005886;GO:0015031;GO:0016567;GO:0051443;GO:0140112;GO:1903561;GO:1990756","-","KOG3780-Thioredoxin binding protein TBP-2/VDUP1[R]"]
["GPT2",45.728237,20.959515,-1.125479965,0,0,"down","GPT2","-","GO:0003824;GO:0004021;GO:0006103;GO:0009058;GO:0030170;GO:0042851","K00814-ko01200 Carbon metabolism;ko01210 2-Oxocarboxylic acid metabolism;ko01230 Biosynthesis of amino acids;ko00710 Carbon fixation in photosynthetic organisms;ko00250 Alanine, aspartate and glutamate metabolism;ko00220 Arginine biosynthesis","KOG0258-Alanine aminotransferase[E]"]
["PGLYRP2",6.310715,2.892457,-1.125507959,{"v":7.91e-11,"d":"7.91E-11"},{"v":1.79e-10,"d":"1.79E-10"},"down","PGLYRP2","peptidoglycan recognition protein 2","GO:0002221;GO:0008270;GO:0008745;GO:0009253;GO:0016019;GO:0016045;GO:0032689;GO:0032827;GO:0042834;GO:0044117;GO:0050727;GO:0050830","-","-"]
["MTPN",140.108063,64.155258,-1.126900568,0,0,"down","MTPN","myotrophin","GO:0005575;GO:0005634;GO:0005737;GO:0005829;GO:0008290;GO:0008361;GO:0010557;GO:0010613;GO:0030307;GO:0030424;GO:0048471;GO:0051092;GO:0051247;GO:2000812","-","KOG4214-Myotrophin and similar proteins[K]"]
["CECR5L",29.86471,13.67178,-1.127240625,{"v":9.13e-96,"d":"9.13E-96"},{"v":5.95e-95,"d":"5.95E-95"},"down","CECR5L","-","GO:0005739;GO:0046474","-","-"]
["TMEM86A",16.030462,7.336586,-1.127635223,{"v":1.12e-113,"d":"1.12E-113"},{"v":8.24e-113,"d":"8.24E-113"},"down","TMEM86A","-","-","-","KOG4804-Predicted membrane protein[R]"]
["TTC38L",29.936583,13.69943,-1.127793692,{"v":6.94e-106,"d":"6.94E-106"},{"v":4.82e-105,"d":"4.82E-105"},"down","TTC38L","-","-","-","-"]
["FAAP100",45.589653,20.858446,-1.12807475,{"v":3.01e-186,"d":"3.01E-186"},{"v":3.12e-185,"d":"3.12E-185"},"down","FAAP100","Fanconi anemia core complex associated protein 100","GO:0005654;GO:0005829;GO:0006281;GO:0043240;GO:0045111","K10993-ko03460 Fanconi anemia pathway","-"]
["PMVK",20.321098,9.294172,-1.128580108,{"v":4.78e-18,"d":"4.78E-18"},{"v":1.33e-17,"d":"1.33E-17"},"down","PMVK","-","GO:0000166;GO:0004631;GO:0005524;GO:0005737;GO:0005777;GO:0005829;GO:0006629;GO:0006694;GO:0006695;GO:0008202;GO:0008203;GO:0016126;GO:0016301;GO:0016310;GO:0016740;GO:0019287;GO:0070723","K13273-ko00900 Terpenoid backbone biosynthesis;ko04146 Peroxisome","-"]
["FSTL3",88.661018,40.537613,-1.129038787,{"v":2.55e-153,"d":"2.55E-153"},{"v":2.29e-152,"d":"2.29E-152"},"down","FSTL3","-","GO:0001968;GO:0002244;GO:0005615;GO:0005634;GO:0005654;GO:0006357;GO:0007507;GO:0022409;GO:0030514;GO:0032926;GO:0045671;GO:0045944;GO:0048185;GO:0090101;GO:1901390","-","-"]
["MBOAT1",33.427616,15.279863,-1.12940886,{"v":1.32e-46,"d":"1.32E-46"},{"v":5.74e-46,"d":"5.74E-46"},"down","MBOAT1","membrane bound O-acyltransferase domain containing 1","GO:0016020;GO:0016021","K13517-ko00561 Glycerolipid metabolism;ko00564 Glycerophospholipid metabolism","KOG2704-Predicted membrane protein[S]"]
["RAB40C",46.311256,21.158224,-1.130144351,{"v":1.59e-46,"d":"1.59E-46"},{"v":6.92e-46,"d":"6.92E-46"},"down","RAB40C","RAB40C, member RAS oncogene family","GO:0003924;GO:0005525;GO:0005622;GO:0016567;GO:0035556","-","KOG0078-GTP-binding protein SEC4, small G protein superfamily, and related Ras family GTP-binding proteins[TU]"]
["SNX2",125.435677,57.290352,-1.130583638,{"v":1.11e-244,"d":"1.11E-244"},{"v":1.43e-243,"d":"1.43E-243"},"down","SNX2","sorting nexin 2","GO:0005154;GO:0005158;GO:0005622;GO:0005737;GO:0005764;GO:0005768;GO:0005829;GO:0006886;GO:0006897;GO:0010008;GO:0016020;GO:0016050;GO:0019898;GO:0030904;GO:0030905;GO:0032991;GO:0034498;GO:0035091;GO:0042147;GO:0042803;GO:0046982;GO:0051259;GO:0072673;GO:1990459;GO:1990460","K17917-ko04144 Endocytosis","KOG2273-Membrane coat complex Retromer, subunit VPS5/SNX1, Sorting nexins, and related PX domain-containing proteins[U]"]
["LMNB1",7.736037,3.532894,-1.130744231,{"v":1.02e-15,"d":"1.02E-15"},{"v":2.67e-15,"d":"2.67E-15"},"down","LMNB1","lamin B1","GO:0005198;GO:0005634;GO:0005635;GO:0005637;GO:0005638;GO:0005654;GO:0005882;GO:0016020;GO:0016363;GO:0031965;GO:0043274","K07611-ko04210 Apoptosis;ko04214 Apoptosis - fly","KOG0977-Nuclear envelope protein lamin, intermediate filament superfamily[DY]"]
["RXFP1",7.815469,3.567939,-1.131241501,{"v":2.52e-34,"d":"2.52E-34"},{"v":9.38e-34,"d":"9.38E-34"},"down","RXFP1","-","GO:0004930;GO:0005886;GO:0007165;GO:0007186;GO:0007188;GO:0007567;GO:0016020;GO:0016021;GO:0030154;GO:0030198;GO:0042562;GO:0060427","K04306-ko04080 Neuroactive ligand-receptor interaction","KOG2087-Glycoprotein hormone receptor[T]"]
["MINPP1",12.69137,5.793737,-1.131281711,{"v":3.46e-21,"d":"3.46E-21"},{"v":1.03e-20,"d":"1.03E-20"},"down","MINPP1","multiple inositol-polyphosphate phosphatase 1","GO:0003993;GO:0004446;GO:0005783;GO:0005788;GO:0016311;GO:0016787;GO:0016791;GO:0034417;GO:0052745;GO:0052826","K03103-ko00010 Glycolysis / Gluconeogenesis;ko00562 Inositol phosphate metabolism","KOG1382-Multiple inositol polyphosphate phosphatase[R]"]
["EGFLAM",30.96767,14.122069,-1.132811368,{"v":8.28e-110,"d":"8.28E-110"},{"v":5.92e-109,"d":"5.92E-109"},"down","EGFLAM","-","GO:0005509;GO:0005539;GO:0005604;GO:0005614;GO:0010811;GO:0019800;GO:0030198;GO:0031012","-","KOG4289-Cadherin EGF LAG seven-pass G-type receptor[T]"]
["SEPT7",314.48111,143.263443,-1.134302842,0,0,"down","SEPT7","septin 7","GO:0000166;GO:0005525;GO:0031105","-","KOG2655-Septin family protein (P-loop GTPase)[DZU]"]
["QSOX1",255.888641,116.555099,-1.134503987,0,0,"down","QSOX1","quiescin Q6 sulfhydryl oxidase 1","GO:0003756;GO:0005615;GO:0005794;GO:0016020;GO:0016021;GO:0016242;GO:0016491;GO:0016971;GO:0016972;GO:0030173;GO:0043231;GO:0045171;GO:0045454;GO:0055114;GO:0070062;GO:0000139;GO:0003756;GO:0005615;GO:0005794;GO:0016020;GO:0016021;GO:0016242;GO:0016491;GO:0016971;GO:0016972;GO:0030173;GO:0043231;GO:0045171;GO:0045454;GO:0055114;GO:0070062","-","KOG1731-FAD-dependent sulfhydryl oxidase/quiescin and related proteins[D]"]
["DPYSL3",46.065811,20.962622,-1.135877232,{"v":1.98e-14,"d":"1.98E-14"},{"v":5.03e-14,"d":"5.03E-14"},"down","DPYSL3","dihydropyrimidinase like 3","GO:0005737;GO:0010975;GO:0016787;GO:0016810;GO:0030334;GO:0031005;GO:0048678;GO:0051017;GO:0051491","-","KOG2584-Dihydroorotase and related enzymes[F]"]
["NMRAL1",899.358948,409.120911,-1.136369754,0,0,"down","NMRAL1","NmrA like redox sensor 1","GO:0005634;GO:0042802;GO:0005634;GO:0005737;GO:0048471","-","-"]
["OSTF1",126.8815,57.715744,-1.136444908,{"v":1.51e-165,"d":"1.51E-165"},{"v":1.44e-164,"d":"1.44E-164"},"down","OSTF1","osteoclast stimulating factor 1","GO:0017124;GO:0005737","-","KOG1118-Lysophosphatidic acid acyltransferase endophilin/SH3GL, involved in synaptic vesicle formation[IT]"]
["CDCP1",30.759985,13.990088,-1.136649762,{"v":2.98e-163,"d":"2.98E-163"},{"v":2.82e-162,"d":"2.82E-162"},"down","CDCP1","-","GO:0016020;GO:0016021","-","-"]
["IRAK2",45.561066,20.709621,-1.137500351,{"v":1.87e-206,"d":"1.87E-206"},{"v":2.13e-205,"d":"2.13E-205"},"down","IRAK2","interleukin 1 receptor associated kinase 2","GO:0001959;GO:0002224;GO:0002755;GO:0004672;GO:0004674;GO:0005524;GO:0005634;GO:0005737;GO:0006468;GO:0006954;GO:0007165;GO:0007249;GO:0031663;GO:0032088;GO:0035556;GO:0042803;GO:0043433;GO:0046982;GO:0051092;GO:0070498;GO:0070555","-","KOG1187-Serine/threonine protein kinase[T]"]
["HECTD4",24.665546,11.205167,-1.138333073,0,0,"down","HECTD4","-","GO:0004842;GO:0016567;GO:0016740","-","KOG0939-E3 ubiquitin-protein ligase/Putative upstream regulatory element binding protein[OK]"]
["CD14",22.467836,10.20023,-1.139259494,{"v":9.86e-38,"d":"9.86E-38"},{"v":3.84e-37,"d":"3.84E-37"},"down","CD14","CD14 molecule","GO:0016020;GO:0016021","-","KOG4194-Membrane glycoprotein LIG-1[T]"]
["SMC4",14.532916,6.593831,-1.14013539,{"v":9.19e-61,"d":"9.19E-61"},{"v":4.59e-60,"d":"4.59E-60"},"down","SMC4","structural maintenance of chromosomes 4","GO:0000796;GO:0003697;GO:0005524;GO:0005634;GO:0005694;GO:0005829;GO:0007076;GO:0010032;GO:0016607;GO:0045132;GO:0046982;GO:0051276;GO:0051383","-","KOG0996-Structural maintenance of chromosome protein 4 (chromosome condensation complex Condensin, subunit C)[BD]"]
["CDK2",28.926146,13.123201,-1.140254454,{"v":7.39e-27,"d":"7.39E-27"},{"v":2.44e-26,"d":"2.44E-26"},"down","CDK2","cyclin dependent kinase 2","GO:0000082;GO:0000122;GO:0000166;GO:0000287;GO:0000307;GO:0000781;GO:0000793;GO:0004672;GO:0004674;GO:0004693;GO:0005524;GO:0005634;GO:0005654;GO:0005667;GO:0005737;GO:0005768;GO:0005813;GO:0006468;GO:0006813;GO:0007099;GO:0007265;GO:0008284;GO:0015030;GO:0016301;GO:0016310;GO:0016572;GO:0018105;GO:0019904;GO:0030332;GO:0032298;GO:0035173;GO:0045893;GO:0051726;GO:0060968;GO:0097123;GO:0097124;GO:0097134;GO:0097135;GO:0097472","K02206-ko04068 FoxO signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04110 Cell cycle;ko04114 Oocyte meiosis;ko04115 p53 signaling pathway;ko04914 Progesterone-mediated oocyte maturation;ko05200 Pathways in cancer;ko05203 Viral carcinogenesis;ko05215 Prostate cancer;ko05222 Small cell lung cancer;ko05162 Measles;ko05161 Hepatitis B;ko05168 Herpes simplex infection;ko05169 Epstein-Barr virus infection","KOG0594-Protein kinase PCTAIRE and related kinases[R]"]
["SPAST",48.327194,21.898922,-1.141975377,{"v":7.31e-108,"d":"7.31E-108"},{"v":5.15e-107,"d":"5.15E-107"},"down","SPAST","spastin","GO:0000166;GO:0005524;GO:0000166;GO:0000281;GO:0001578;GO:0005524;GO:0005634;GO:0005654;GO:0005737;GO:0005768;GO:0005783;GO:0005813;GO:0005815;GO:0005819;GO:0005829;GO:0005856;GO:0005874;GO:0006888;GO:0007049;GO:0007275;GO:0007399;GO:0007409;GO:0008017;GO:0008089;GO:0008568;GO:0010458;GO:0015630;GO:0016020;GO:0016021;GO:0016787;GO:0016887;GO:0019896;GO:0030154;GO:0030496;GO:0031117;GO:0031410;GO:0031468;GO:0031965;GO:0032467;GO:0032506;GO:0034214;GO:0043014;GO:0048471;GO:0048487;GO:0051013;GO:0051228;GO:0051260;GO:0051301;GO:0090148;GO:1904115","-","KOG0740-AAA+-type ATPase[O]"]
["SLC25A17",41.691391,18.880428,-1.142858038,{"v":4.27e-63,"d":"4.27E-63"},{"v":2.17e-62,"d":"2.17E-62"},"down","SLC25A17","-","GO:0005347;GO:0005743;GO:0005777;GO:0005778;GO:0005779;GO:0006635;GO:0006839;GO:0015217;GO:0015228;GO:0015230;GO:0015858;GO:0015866;GO:0015867;GO:0015908;GO:0016020;GO:0016021;GO:0035349;GO:0035350;GO:0035352;GO:0044610;GO:0051087;GO:0051182;GO:0051724;GO:0055085;GO:0080121;GO:0080122;GO:1901679","K13354-ko04146 Peroxisome","KOG0769-Predicted mitochondrial carrier protein[C]"]
["RNF149",116.615921,52.804333,-1.143036542,0,0,"down","RNF149","-","GO:0016020;GO:0016021;GO:0016567;GO:0031647;GO:0035690;GO:0043409;GO:0061630","-","KOG4628-Predicted E3 ubiquitin ligase[O]"]
["N4BP3",21.94882,9.936542,-1.143327606,{"v":1.53e-66,"d":"1.53E-66"},{"v":8.03e-66,"d":"8.03E-66"},"down","N4BP3","NEDD4 binding protein 3","GO:0031410;GO:0007275;GO:0007399;GO:0030424;GO:0030425;GO:0031410;GO:0042995","-","-"]
["RABGGTB",35.803268,16.197678,-1.144304266,{"v":4.25e-110,"d":"4.25E-110"},{"v":3.04e-109,"d":"3.04E-109"},"down","RABGGTB","-","GO:0003824;GO:0004663;GO:0005968;GO:0018344","-","KOG0366-Protein geranylgeranyltransferase type II, beta subunit[O]"]
["TEAD1",46.294811,20.942648,-1.144406628,{"v":2.38e-140,"d":"2.38E-140"},{"v":2.02e-139,"d":"2.02E-139"},"down","TEAD1","TEA domain transcription factor 1","GO:0000978;GO:0001085;GO:0003677;GO:0003700;GO:0005634;GO:0005654;GO:0005667;GO:0006351;GO:0006355;GO:0006366;GO:0035329;GO:0043565;GO:0044212;GO:0045944;GO:0048568","-","KOG3841-TEF-1 and related transcription factor, TEAD family[K]"]
["TLE4Z1",17.295717,7.820693,-1.145046465,{"v":4.03e-79,"d":"4.03E-79"},{"v":2.33e-78,"d":"2.33E-78"},"down","TLE4Z1","transducin like enhancer of split 4-Z 1","GO:0001709;GO:0003002;GO:0005634;GO:0006355;GO:0007164;GO:0010628;GO:0010629;GO:0030901;GO:0048859","-","-"]
["FOXN2",15.223767,6.864852,-1.149024864,{"v":3.97e-85,"d":"3.97E-85"},{"v":2.41e-84,"d":"2.41E-84"},"down","FOXN2","forkhead box N2","GO:0003677;GO:0003700;GO:0005634;GO:0006355;GO:0030154;GO:0035914;GO:0043231;GO:0043565;GO:0045893","-","KOG2294-Transcription factor of the Forkhead/HNF3 family[K]"]
["ASAP2",12.294505,5.53681,-1.15088673,{"v":1.34e-44,"d":"1.34E-44"},{"v":5.69e-44,"d":"5.69E-44"},"down","ASAP2","-","GO:0005096;GO:0043547;GO:0046872","K12488-ko04144 Endocytosis;ko04666 Fc gamma R-mediated phagocytosis","KOG0521-Putative GTPase activating proteins (GAPs)[T]"]
["PARD3",42.269073,19.010719,-1.152789376,{"v":2.96e-194,"d":"2.96E-194"},{"v":3.17e-193,"d":"3.17E-193"},"down","PARD3","par-3 family cell polarity regulator","GO:0005911;GO:0005923;GO:0030054","K04237-ko04015 Rap1 signaling pathway;ko04390 Hippo signaling pathway;ko04391 Hippo signaling pathway -fly;ko04080 Neuroactive ligand-receptor interaction;ko04144 Endocytosis;ko04520 Adherens junction;ko04530 Tight junction;ko04062 Chemokine signaling pathway","KOG3209-WW domain-containing protein[R]"]
["GJC1",21.76652,9.786882,-1.15318956,{"v":7e-41,"d":"7.00E-41"},{"v":2.86e-40,"d":"2.86E-40"},"down","GJC1","gap junction protein gamma 1","GO:0001570;GO:0005216;GO:0005886;GO:0005921;GO:0005922;GO:0007154;GO:0007267;GO:0007268;GO:0007507;GO:0007601;GO:0016020;GO:0016021;GO:0016264;GO:0030054;GO:0034220;GO:0048468;GO:0048738;GO:0086053;GO:0086077","-","-"]
["SDC4",352.819275,158.585739,-1.153666339,{"v":8.4e-209,"d":"8.40E-209"},{"v":9.59e-208,"d":"9.59E-208"},"down","SDC4","syndecan 4","GO:0001843;GO:0009986;GO:0010762;GO:0016020;GO:0016021;GO:0016477;GO:0042060;GO:0042130;GO:0042802;GO:0044319;GO:0060122;GO:0061098;GO:0070053;GO:0090630;GO:1902723;GO:1902725;GO:1902766;GO:1903076;GO:1903078;GO:1903543;GO:1903553","K16338-ko04512 ECM-receptor interaction;ko04514 Cell adhesion molecules (CAMs);ko05205 Proteoglycans in cancer","-"]
["EGLN3",10.304354,4.630652,-1.153966817,{"v":3.97e-50,"d":"3.97E-50"},{"v":1.79e-49,"d":"1.79E-49"},"down","EGLN3","-","GO:0001666;GO:0005506;GO:0005634;GO:0005737;GO:0005829;GO:0006915;GO:0006919;GO:0016491;GO:0016705;GO:0016706;GO:0018126;GO:0018401;GO:0031418;GO:0031545;GO:0042127;GO:0046872;GO:0055114","-","KOG3710-EGL-Nine (EGLN) protein[T]"]
["COA4",14.702461,6.602284,-1.15502056,{"v":1.64e-10,"d":"1.64E-10"},{"v":3.66e-10,"d":"3.66E-10"},"down","COA4","-","-","-","KOG4138-Unchracterized conserved protein (estrogen up-regulated protein E2IG2 in human)[R]"]
["EHHADH",21.955816,9.844271,-1.157246875,{"v":5.39e-75,"d":"5.39E-75"},{"v":3.02e-74,"d":"3.02E-74"},"down","EHHADH","-","GO:0003824;GO:0003857;GO:0005102;GO:0005777;GO:0006475;GO:0006631;GO:0006635;GO:0008152;GO:0016491;GO:0019899;GO:0055114","K07514-ko01200 Carbon metabolism;ko01212 Fatty acid metabolism;ko00640 Propanoate metabolism;ko00650 Butanoate metabolism;ko00071 Fatty acid degradation;ko00280 Valine, leucine and isoleucine degradation;ko00310 Lysine degradation;ko00380 Tryptophan metabolism;ko00410 beta-Alanine metabolism;ko00627 Aminobenzoate degradation;ko00930 Caprolactam degradation;ko04146 Peroxisome;ko03320 PPAR signaling pathway","KOG1683-Hydroxyacyl-CoA dehydrogenase/enoyl-CoA hydratase[I]"]
["DLGAP5",11.104491,4.974632,-1.158481554,{"v":3.06e-43,"d":"3.06E-43"},{"v":1.28e-42,"d":"1.28E-42"},"down","DLGAP5","-","GO:0004721;GO:0005634;GO:0005739;GO:0005815;GO:0005829;GO:0006470;GO:0023052;GO:0031616","-","KOG3971-SAP-90/PSD-95 associated protein-related protein (Vulcan)[T]"]
["GJB3",44.326668,19.851505,-1.158926534,{"v":6.54e-82,"d":"6.54E-82"},{"v":3.87e-81,"d":"3.87E-81"},"down","GJB3","-","-","-","-"]
["CD109",11.176575,5.003228,-1.159547047,{"v":7.91e-154,"d":"7.91E-154"},{"v":7.15e-153,"d":"7.15E-153"},"down","CD109","-","GO:0001933;GO:0004866;GO:0005576;GO:0005615;GO:0010839;GO:0010951;GO:0030512;GO:0045616;GO:0050431;GO:0061045;GO:0072675","-","KOG1366-Alpha-macroglobulin[O]"]
["UBE2E2",35.810589,16.019342,-1.160571358,{"v":3.07e-49,"d":"3.07E-49"},{"v":1.37e-48,"d":"1.37E-48"},"down","UBE2E2","-","GO:0000166;GO:0004842;GO:0005524;GO:0006974;GO:0016740;GO:0032020;GO:0042296;GO:0061631;GO:0070534;GO:0070936;GO:0070979;GO:1900087","K20217-ko04120 Ubiquitin mediated proteolysis","KOG0417-Ubiquitin-protein ligase[O]"]
["DGCR2",32.317135,14.453378,-1.160892591,{"v":9.72e-230,"d":"9.72E-230"},{"v":1.19e-228,"d":"1.19E-228"},"down","DGCR2","-","GO:0016020;GO:0016021;GO:0050890","-","-"]
["GNG10",76.715752,34.298763,-1.16136629,{"v":4.03e-88,"d":"4.03E-88"},{"v":2.5e-87,"d":"2.50E-87"},"down","GNG10","G protein subunit gamma 10","GO:0003924;GO:0005834;GO:0005886;GO:0007165;GO:0007186;GO:0016020","K04545-ko04014 Ras signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04062 Chemokine signaling pathway;ko04724 Glutamatergic synapse;ko04727 GABAergic synapse;ko04725 Cholinergic synapse;ko04728 Dopaminergic synapse;ko04726 Serotonergic synapse;ko04723 Retrograde endocannabinoid signaling;ko04713 Circadian entrainment;ko05200 Pathways in cancer;ko05032 Morphine addiction;ko05034 Alcoholism","KOG4119-G protein gamma subunit[T]"]
["PLTP",14.54899,6.500033,-1.162400056,{"v":9.01e-23,"d":"9.01E-23"},{"v":2.76e-22,"d":"2.76E-22"},"down","PLTP","phospholipid transfer protein","GO:0005319;GO:0005548;GO:0006629;GO:0006869;GO:0008289;GO:0008429;GO:0008525;GO:0010189;GO:0010875;GO:0015914;GO:0019992;GO:0030317;GO:0031210;GO:0034364;GO:0034375;GO:0035620;GO:0035627;GO:0070300;GO:0097001;GO:1901611;GO:1904121;GO:1990050","K08761-ko03320 PPAR signaling pathway","KOG4160-BPI/LBP/CETP family protein[V]"]
["KIAA1324",9.071839,4.050016,-1.163467429,{"v":9.17e-38,"d":"9.17E-38"},{"v":3.58e-37,"d":"3.58E-37"},"down","KIAA1324","-","GO:0000045;GO:0005764;GO:0005770;GO:0005802;GO:0005886;GO:0005887;GO:0009267;GO:0044090;GO:2000786","-","-"]
["REM1",12.369893,5.511571,-1.166297517,{"v":2.74e-21,"d":"2.74E-21"},{"v":8.17e-21,"d":"8.17E-21"},"down","REM1","-","GO:0005509;GO:0005515;GO:0046872;GO:0000166;GO:0003924;GO:0005525;GO:0007165;GO:0016020;GO:1901842","-","KOG0395-Ras-related GTPase[R]"]
["ESPN",18.734224,8.344032,-1.166859624,{"v":8.13e-58,"d":"8.13E-58"},{"v":3.97e-57,"d":"3.97E-57"},"down","ESPN","-","-","-","-"]
["FAM210B",28.064188,12.499319,-1.166880823,{"v":6.81e-83,"d":"6.81E-83"},{"v":4.06e-82,"d":"4.06E-82"},"down","FAM210B","family with sequence similarity 210 member B","GO:0005741;GO:0016020;GO:0016021;GO:0031224;GO:0045648;GO:0071392","-","KOG4526-Predicted membrane protein[S]"]
["EHF",75.644478,33.671875,-1.167690711,{"v":1.42e-124,"d":"1.42E-124"},{"v":1.11e-123,"d":"1.11E-123"},"down","EHF","ETS homologous factor","GO:0000978;GO:0000981;GO:0003677;GO:0003700;GO:0005634;GO:0005654;GO:0005794;GO:0006355;GO:0006357;GO:0006366;GO:0030154;GO:0030855;GO:0043565;GO:0045893;GO:0045944;GO:0050673","-","KOG3804-Transcription factor NERF and related proteins, contain ETS domain[K]"]
["CORO2B",8.566483,3.81307,-1.167750006,{"v":5.47e-25,"d":"5.47E-25"},{"v":1.75e-24,"d":"1.75E-24"},"down","CORO2B","-","GO:0015629;GO:0016020;GO:0030036;GO:0051015","-","KOG0303-Actin-binding protein Coronin, contains WD40 repeats[Z]"]
["GPI",360.574005,160.444534,-1.168220751,0,0,"down","GPI","glucose-6-phosphate isomerase","GO:0001707;GO:0004347;GO:0005654;GO:0005829;GO:0005886;GO:0006094;GO:0006096;GO:0016853;GO:0034101;GO:0042593;GO:0043209;GO:0060170","K01810-ko01200 Carbon metabolism;ko00010 Glycolysis / Gluconeogenesis;ko00030 Pentose phosphate pathway;ko00500 Starch and sucrose metabolism;ko00520 Amino sugar and nucleotide sugar metabolism","KOG2446-Glucose-6-phosphate isomerase[G]"]
["CD44",88.595795,39.370369,-1.170127992,0,0,"down","CD44","CD44 molecule (Indian blood group)","GO:0004896;GO:0005540;GO:0005794;GO:0005829;GO:0005886;GO:0007155;GO:0009986;GO:0016020;GO:0016021;GO:0016324;GO:0019221;GO:0030214;GO:0031258;GO:0033138;GO:0034116;GO:0035692;GO:0042995;GO:0043066;GO:0043154;GO:0043518;GO:0044319;GO:0044344;GO:0050731;GO:0051216;GO:0070374;GO:0070487;GO:1900625;GO:1902166;GO:2000392","K06256-ko04512 ECM-receptor interaction;ko04640 Hematopoietic cell lineage;ko05206 MicroRNAs in cancer;ko05205 Proteoglycans in cancer;ko05131 Shigellosis;ko05169 Epstein-Barr virus infection","-"]
["TMEM125",24.79155,11.016157,-1.170227448,{"v":6.38e-84,"d":"6.38E-84"},{"v":3.84e-83,"d":"3.84E-83"},"down","TMEM125","-","GO:0016020;GO:0016021","-","-"]
["SDPR",462.316589,205.385422,-1.170547346,0,0,"down","SDPR","-","GO:0005080;GO:0005737;GO:0005901","-","-"]
["TNFAIP8L3",23.541506,10.43236,-1.174141056,{"v":1.86e-80,"d":"1.86E-80"},{"v":1.08e-79,"d":"1.08E-79"},"down","TNFAIP8L3","-","GO:0005737;GO:0042981","-","-"]
["APOD",19.547497,8.653968,-1.175550195,{"v":3.05e-21,"d":"3.05E-21"},{"v":9.07e-21,"d":"9.07E-21"},"down","APOD","apolipoprotein D","-","-","KOG4824-Apolipoprotein D/Lipocalin[M]"]
["ENPP6",20.36356,9.013469,-1.175835433,{"v":4.06e-90,"d":"4.06E-90"},{"v":2.54e-89,"d":"2.54E-89"},"down","ENPP6","-","GO:0003824;GO:0005576;GO:0005886;GO:0006629;GO:0008081;GO:0008152;GO:0008889;GO:0019695;GO:0047390","K08743-ko00565 Ether lipid metabolism","KOG2645-Type I phosphodiesterase/nucleotide pyrophosphatase[R]"]
["MAX",57.210274,25.295202,-1.177410494,{"v":3.14e-77,"d":"3.14E-77"},{"v":1.79e-76,"d":"1.79E-76"},"down","MAX","-","GO:0003677;GO:0005634;GO:0006351;GO:0006355;GO:0046983;GO:0071339;GO:0090575","K04453-ko04010 MAPK signaling pathway;ko05200 Pathways in cancer;ko05202 Transcriptional misregulation in cancers;ko05222 Small cell lung cancer","KOG2483-Upstream transcription factor 2/L-myc-2 protein[K]"]
["EDEM1",62.279694,27.535463,-1.177470989,{"v":1.93e-141,"d":"1.93E-141"},{"v":1.65e-140,"d":"1.65E-140"},"down","EDEM1","ER degradation enhancing alpha-mannosidase like protein 1","GO:0003824;GO:0004571;GO:0005509;GO:0005783;GO:0008152;GO:0016020;GO:0016235;GO:0016787;GO:0016798;GO:0030176;GO:0030433;GO:0036510;GO:0044322;GO:0051787;GO:0097466;GO:1904154;GO:1904382","K10084-ko04141 Protein processing in endoplasmic reticulum","KOG2429-Glycosyl hydrolase, family 47[G]"]
["DPY19L1",30.092678,13.257614,-1.182591346,{"v":2.62e-131,"d":"2.62E-131"},{"v":2.12e-130,"d":"2.12E-130"},"down","DPY19L1","-","GO:0016020;GO:0016021","-","-"]
["RANBP10",74.892532,32.983147,-1.183092809,{"v":5.91e-130,"d":"5.91E-130"},{"v":4.74e-129,"d":"4.74E-129"},"down","RANBP10","-","GO:0000151","-","KOG1477-SPRY domain-containing proteins[R]"]
["ANKRD39",46.083206,20.294796,-1.18313125,{"v":4.04e-37,"d":"4.04E-37"},{"v":1.56e-36,"d":"1.56E-36"},"down","ANKRD39","-","-","-","KOG0509-Ankyrin repeat and DHHC-type Zn-finger domain containing proteins[R]"]
["LIM2",14.270164,6.283067,-1.183461046,{"v":1.51e-39,"d":"1.51E-39"},{"v":6.04e-39,"d":"6.04E-39"},"down","LIM2","-","-","-","-"]
["ADARB1",22.0693,9.711653,-1.184252091,{"v":6.42e-48,"d":"6.42E-48"},{"v":2.84e-47,"d":"2.84E-47"},"down","ADARB1","adenosine deaminase, RNA specific B1","GO:0003723;GO:0004000;GO:0005634;GO:0005654;GO:0005730;GO:0005829;GO:0006382;GO:0006396;GO:0007274;GO:0008285;GO:0021610;GO:0021618;GO:0021965;GO:0030336;GO:0035264;GO:0044387;GO:0045070;GO:0050884;GO:0051726;GO:0060384;GO:0060415;GO:0061744;GO:0097049;GO:0003723;GO:0004000;GO:0006396","-","KOG2777-tRNA-specific adenosine deaminase 1[A]"]
["SATB1",9.540479,4.19312,-1.186037583,{"v":2.49e-38,"d":"2.49E-38"},{"v":9.79e-38,"d":"9.79E-38"},"down","SATB1","SATB homeobox 1","GO:0000122;GO:0000785;GO:0000977;GO:0001227;GO:0003677;GO:0003682;GO:0003700;GO:0005634;GO:0005654;GO:0005720;GO:0006325;GO:0006338;GO:0006351;GO:0006355;GO:0006357;GO:0008544;GO:0016363;GO:0016571;GO:0016604;GO:0016605;GO:0042110;GO:0043367;GO:0043374;GO:0043565;GO:0050798;GO:0060004","-","KOG3755-SATB1 matrix attachment region binding protein[K]"]
["TSPAN15",78.688721,34.578415,-1.186285119,{"v":8.59e-158,"d":"8.59E-158"},{"v":7.89e-157,"d":"7.89E-157"},"down","TSPAN15","tetraspanin 15","GO:0005886;GO:0005887;GO:0007166;GO:0009986;GO:0016020;GO:0016021;GO:0019899;GO:0051604;GO:0072659;GO:0097197","-","KOG3882-Tetraspanin family integral membrane protein[R]"]
["EDEM3",56.671017,24.895092,-1.186749746,0,0,"down","EDEM3","-","GO:0003824;GO:0004571;GO:0005509;GO:0005783;GO:0005788;GO:0006491;GO:0006516;GO:0008152;GO:0016020;GO:0016787;GO:0016798;GO:0030968;GO:0043161;GO:1904382","K10086-ko04141 Protein processing in endoplasmic reticulum","KOG2430-Glycosyl hydrolase, family 47[G]"]
["PTPRZ1",8.267997,3.631001,-1.187170538,{"v":2e-30,"d":"2.00E-30"},{"v":7.01e-30,"d":"7.01E-30"},"down","PTPRZ1","protein tyrosine phosphatase, receptor type Z1","GO:0002244;GO:0004721;GO:0004725;GO:0006470;GO:0007409;GO:0007611;GO:0016020;GO:0016021;GO:0016311;GO:0016787;GO:0016791;GO:0031012;GO:0035335;GO:0045177;GO:0045202;GO:0048709;GO:0070445;GO:0072534","-","KOG4228-Protein tyrosine phosphatase[T]"]
["CHTF18",20.441093,8.974862,-1.187510679,{"v":9.63e-67,"d":"9.63E-67"},{"v":5.05e-66,"d":"5.05E-66"},"down","CHTF18","chromosome transmission fidelity factor 18","GO:0003689;GO:0005524;GO:0005654;GO:0005829;GO:0031390;GO:0043142;GO:1900264","-","KOG1969-DNA replication checkpoint protein CHL12/CTF18[DL]"]
["VPS4B",67.653511,29.694813,-1.18795386,{"v":7.77e-249,"d":"7.77E-249"},{"v":1.02e-247,"d":"1.02E-247"},"down","VPS4B","vacuolar protein sorting 4 homolog B","GO:0000166;GO:0000920;GO:0000922;GO:0005524;GO:0005634;GO:0005737;GO:0005768;GO:0005813;GO:0005829;GO:0006813;GO:0006997;GO:0007032;GO:0007080;GO:0008022;GO:0010008;GO:0010824;GO:0010971;GO:0016197;GO:0016887;GO:0019076;GO:0030301;GO:0032510;GO:0033993;GO:0036258;GO:0039702;GO:0042623;GO:0042802;GO:0042803;GO:0043162;GO:0048524;GO:0050792;GO:0051261;GO:0060548;GO:0061738;GO:0090543;GO:0090611;GO:1901673;GO:1902188;GO:1903542;GO:1903543;GO:1903724;GO:1903902;GO:0000166;GO:0005524;GO:0005634;GO:0016887","K12196-ko04144 Endocytosis","KOG0739-AAA+-type ATPase[O]"]
["LOC112533523",9.213577,4.037233,-1.190394513,0.010876367,0.015145866,"down","LOC112533523","-","-","-","-"]
["DDO",7.323838,3.208985,-1.190482834,{"v":1.5e-17,"d":"1.50E-17"},{"v":4.11e-17,"d":"4.11E-17"},"down","DDO","-","GO:0003884;GO:0005102;GO:0005829;GO:0006531;GO:0007320;GO:0007625;GO:0008445;GO:0016491;GO:0019478;GO:0042445;GO:0046416;GO:0048037;GO:0055114;GO:0071949","K00272-ko00250 Alanine, aspartate and glutamate metabolism;ko04146 Peroxisome","KOG3923-D-aspartate oxidase[E]"]
["GATSL3",25.582079,11.20568,-1.190903314,{"v":2.32e-44,"d":"2.32E-44"},{"v":9.87e-44,"d":"9.87E-44"},"down","GATSL3","-","GO:0005829;GO:0034618;GO:0042802;GO:0061700;GO:1903432;GO:1903577;GO:1904262","-","-"]
["MVK",27.584761,12.078419,-1.191439855,{"v":1.39e-64,"d":"1.39E-64"},{"v":7.16e-64,"d":"7.16E-64"},"down","MVK","-","GO:0000166;GO:0004496;GO:0005524;GO:0005737;GO:0005829;GO:0006629;GO:0006694;GO:0006695;GO:0008202;GO:0008203;GO:0008299;GO:0016126;GO:0016301;GO:0016310;GO:0016740;GO:0019287;GO:0042802;GO:0050728","K00869-ko00900 Terpenoid backbone biosynthesis;ko04146 Peroxisome","KOG1511-Mevalonate kinase MVK/ERG12[I]"]
["DYNLL1",57.172192,25.020836,-1.192183611,{"v":1.1e-37,"d":"1.10E-37"},{"v":4.28e-37,"d":"4.28E-37"},"down","DYNLL1","-","GO:0000776;GO:0003774;GO:0005634;GO:0005737;GO:0005813;GO:0005856;GO:0005868;GO:0005874;GO:0005875;GO:0007017;GO:0008092;GO:0008180;GO:0008574;GO:0010970;GO:0030286;GO:0042326;GO:0045505;GO:0051959;GO:0060271;GO:0072686;GO:2000582","-","KOG3430-Dynein light chain type 1[Z]"]
["UNG",12.84163,5.619214,-1.192388087,{"v":1.24e-14,"d":"1.24E-14"},{"v":3.15e-14,"d":"3.15E-14"},"down","UNG","uracil DNA glycosylase","GO:0004844;GO:0005634;GO:0005739;GO:0006281;GO:0006284;GO:0006974;GO:0016787;GO:0016799;GO:0004844;GO:0005634;GO:0005739;GO:0006281;GO:0006284;GO:0006974;GO:0016787;GO:0016799;GO:0097510","K03648-ko03410 Base excision repair;ko05340 Primary immunodeficiency","KOG2994-Uracil DNA glycosylase[L]"]
["VSIG10",113.753624,49.758698,-1.192891867,{"v":2.76e-205,"d":"2.76E-205"},{"v":3.12e-204,"d":"3.12E-204"},"down","VSIG10","-","GO:0016020;GO:0016021","-","KOG3513-Neural cell adhesion molecule L1[T]"]
["ITPR1",19.435595,8.49675,-1.193718253,{"v":1.34e-183,"d":"1.34E-183"},{"v":1.38e-182,"d":"1.38E-182"},"down","ITPR1","inositol 1,4,5-trisphosphate receptor type 1","GO:0001666;GO:0005216;GO:0005220;GO:0005262;GO:0005509;GO:0005635;GO:0005637;GO:0005730;GO:0005737;GO:0005783;GO:0005789;GO:0005886;GO:0005955;GO:0006811;GO:0006816;GO:0009791;GO:0014069;GO:0015278;GO:0016020;GO:0016021;GO:0016529;GO:0019855;GO:0031088;GO:0031094;GO:0032469;GO:0032991;GO:0035091;GO:0042045;GO:0048016;GO:0050849;GO:0050882;GO:0051209;GO:0055085;GO:0070059;GO:0070588;GO:0070679","K04958-ko04020 Calcium signaling pathway;ko04070 Phosphatidylinositol signaling system;ko04022 cGMP - PKG signaling pathway;ko04114 Oocyte meiosis;ko04210 Apoptosis;ko04540 Gap junction;ko04611 Platelet activation;ko04922 Glucagon signaling pathway;ko04912 GnRH signaling pathway;ko04915 Estrogen signaling pathway;ko04921 Oxytocin signaling pathway;ko04918 Thyroid hormone synthesis;ko04924 Renin secretion;ko04925 Aldosterone synthesis and secretion;ko04270 Vascular smooth muscle contraction;ko04970 Salivary secretion;ko04971 Gastric acid secretion;ko04972 Pancreatic secretion;ko04724 Glutamatergic synapse;ko04725 Cholinergic synapse;ko04728 Dopaminergic synapse;ko04726 Serotonergic synapse;ko04720 Long-term potentiation;ko04730 Long-term depression;ko04723 Retrograde endocannabinoid signaling;ko04745 Phototransduction - fly;ko04750 Inflammatory mediator regulation of TRP channels;ko04713 Circadian entrainment;ko05205 Proteoglycans in cancer;ko05010 Alzheimer's disease;ko05016 Huntington's disease","KOG3533-Inositol 1,4,5-trisphosphate receptor[T]"]
["LRRC73",12.384882,5.412791,-1.194135534,{"v":2.78e-20,"d":"2.78E-20"},{"v":8.08e-20,"d":"8.08E-20"},"down","LRRC73","leucine rich repeat containing 73","-","-","KOG4308-LRR-containing protein[S]"]
["DENND2D",18.965603,8.28743,-1.194388557,{"v":2.16e-65,"d":"2.16E-65"},{"v":1.12e-64,"d":"1.12E-64"},"down","DENND2D","-","-","-","KOG3569-RAS signaling inhibitor ST5[T]"]
["PSMG4",60.020794,26.220121,-1.194788061,{"v":1.21e-37,"d":"1.21E-37"},{"v":4.7e-37,"d":"4.70E-37"},"down","PSMG4","-","GO:0043248","-","-"]
["UGT1A1",13.165565,5.746482,-1.196018523,{"v":4.11e-59,"d":"4.11E-59"},{"v":2.03e-58,"d":"2.03E-58"},"down","UGT1A1","-","GO:0008152;GO:0015020;GO:0016020;GO:0016021;GO:0016740;GO:0016757;GO:0016758;GO:0043231;GO:0052696;GO:0052697","K00699-ko00040 Pentose and glucuronate interconversions;ko00053 Ascorbate and aldarate metabolism;ko00500 Starch and sucrose metabolism;ko00140 Steroid hormone biosynthesis;ko00830 Retinol metabolism;ko00860 Porphyrin and chlorophyll metabolism;ko00980 Metabolism of xenobiotics by cytochrome P450;ko00982 Drug metabolism - cytochrome P450;ko00983 Drug metabolism - other enzymes;ko05204 Chemical carcinogenesis","KOG1192-UDP-glucuronosyl and UDP-glucosyl transferase[GC]"]
["B3GALNT2",52.666988,22.965733,-1.197416124,{"v":7.22e-229,"d":"7.22E-229"},{"v":8.85e-228,"d":"8.85E-228"},"down","B3GALNT2","-","GO:0000139;GO:0005783;GO:0005794;GO:0006486;GO:0006493;GO:0008375;GO:0008376;GO:0008378;GO:0016020;GO:0016021;GO:0016740;GO:0016757","-","KOG2287-Galactosyltransferases[G]"]
["GSR",123.476234,53.837765,-1.197542962,{"v":2.59e-218,"d":"2.59E-218"},{"v":3.06e-217,"d":"3.06E-217"},"down","GSR","-","GO:0004362;GO:0005623;GO:0005737;GO:0006749;GO:0009055;GO:0009897;GO:0016491;GO:0016668;GO:0022900;GO:0045454;GO:0050660;GO:0050661;GO:0055114;GO:0098869","K00383-ko00480 Glutathione metabolism;ko04918 Thyroid hormone synthesis","KOG0405-Pyridine nucleotide-disulphide oxidoreductase[Q]"]
["LOC422757",148.72142,64.822723,-1.19804092,{"v":3.57e-112,"d":"3.57E-112"},{"v":2.59e-111,"d":"2.59E-111"},"down","LOC422757","-","-","-","-"]
["BUB1B",8.053423,3.505949,-1.199797102,{"v":1.96e-33,"d":"1.96E-33"},{"v":7.2e-33,"d":"7.20E-33"},"down","BUB1B","BUB1 mitotic checkpoint serine/threonine kinase B","GO:0000776;GO:0000777;GO:0000778;GO:0000940;GO:0005737;GO:0005829;GO:0007091;GO:0007094;GO:0034501;GO:0048471;GO:0071459","K06637-ko04110 Cell cycle;ko05166 HTLV-I infection","KOG1166-Mitotic checkpoint serine/threonine protein kinase[D]"]
["P4HA3",22.022503,9.572427,-1.202021792,{"v":6.03e-56,"d":"6.03E-56"},{"v":2.89e-55,"d":"2.89E-55"},"down","P4HA3","-","GO:0005506;GO:0016491;GO:0016705;GO:0031418;GO:0046872;GO:0055114","K00472-ko00330 Arginine and proline metabolism","KOG1591-Prolyl 4-hydroxylase alpha subunit[E]"]
["PPP3R1",179.264191,77.900337,-1.202385856,0,0,"down","PPP3R1","protein phosphatase 3 regulatory subunit B, alpha","GO:0001569;GO:0001837;GO:0004721;GO:0005509;GO:0005955;GO:0006470;GO:0006606;GO:0007507;GO:0014044;GO:0019902;GO:0022011;GO:0033173;GO:0034504;GO:0042383;GO:0045202;GO:0060487;GO:0098685;GO:0098688;GO:0098794;GO:0098978;GO:0099149;GO:0099170","K06268-ko04010 MAPK signaling pathway;ko04310 Wnt signaling pathway;ko04370 VEGF signaling pathway;ko04020 Calcium signaling pathway;ko04022 cGMP - PKG signaling pathway;ko04114 Oocyte meiosis;ko04650 Natural killer cell mediated cytotoxicity;ko04660 T cell receptor signaling pathway;ko04662 B cell receptor signaling pathway;ko04922 Glucagon signaling pathway;ko04921 Oxytocin signaling pathway;ko04924 Renin secretion;ko04724 Glutamatergic synapse;ko04720 Long-term potentiation;ko04360 Axon guidance;ko04380 Osteoclast differentiation;ko05010 Alzheimer's disease;ko05014 Amyotrophic lateral sclerosis (ALS);ko05031 Amphetamine addiction;ko05152 Tuberculosis;ko05166 HTLV-I infection","KOG0034-Ca2+/calmodulin-dependent protein phosphatase (calcineurin subunit B), EF-Hand superfamily protein[T]"]
["FNDC1",36.339828,15.790849,-1.202462851,{"v":2.55e-254,"d":"2.55E-254"},{"v":3.39e-253,"d":"3.39E-253"},"down","FNDC1","-","GO:0016607","-","KOG4221-Receptor mediating netrin-dependent axon guidance[T]"]
["GNB5",11.068142,4.806928,-1.203225959,{"v":4.93e-38,"d":"4.93E-38"},{"v":1.93e-37,"d":"1.93E-37"},"down","GNB5","G protein subunit beta 5","GO:0001750;GO:0001917;GO:0005096;GO:0005634;GO:0005829;GO:0005886;GO:0007165;GO:0007186;GO:0007212;GO:0031682;GO:0043209;GO:0043547;GO:0051087;GO:0098793;GO:1901386","K04539-ko04014 Ras signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04062 Chemokine signaling pathway;ko04724 Glutamatergic synapse;ko04727 GABAergic synapse;ko04725 Cholinergic synapse;ko04728 Dopaminergic synapse;ko04726 Serotonergic synapse;ko04723 Retrograde endocannabinoid signaling;ko04713 Circadian entrainment;ko05200 Pathways in cancer;ko05032 Morphine addiction;ko05034 Alcoholism","KOG0286-G-protein beta subunit[R]"]
["CDH3",60.631237,26.319435,-1.203932738,{"v":2.31e-183,"d":"2.31E-183"},{"v":2.37e-182,"d":"2.37E-182"},"down","CDH3","-","GO:0005509;GO:0005886;GO:0007155;GO:0007156;GO:0016020;GO:0016021","K06796-ko04514 Cell adhesion molecules (CAMs)","-"]
["ITGB5",94.466736,40.99876,-1.204226135,{"v":3.48e-305,"d":"3.48E-305"},{"v":5.35e-304,"d":"5.35E-304"},"down","ITGB5","integrin subunit beta 5","GO:0007155;GO:0007160;GO:0007179;GO:0007229;GO:0008305;GO:0009986;GO:0016020;GO:0016021;GO:0034684;GO:0035987;GO:0038023;GO:0043149;GO:0043235;GO:0090136","K06588-ko04151 PI3K-Akt signaling pathway;ko04512 ECM-receptor interaction;ko04145 Phagosome;ko04810 Regulation of actin cytoskeleton;ko04510 Focal adhesion;ko05205 Proteoglycans in cancer;ko05410 Hypertrophic cardiomyopathy (HCM);ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC);ko05414 Dilated cardiomyopathy (DCM)","KOG1226-Integrin beta subunit (N-terminal portion of extracellular region)[TW]"]
["HECA",103.988045,45.104225,-1.205083193,0,0,"down","HECA","-","GO:0005634;GO:0005737;GO:0045930","-","KOG3816-Cell differentiation regulator of the Headcase family[T]"]
["FAM83F",9.573087,4.151102,-1.205489839,{"v":1.04e-57,"d":"1.04E-57"},{"v":5.09e-57,"d":"5.09E-57"},"down","FAM83F","-","-","-","-"]
["RASEF",27.787504,12.048913,-1.205533252,{"v":1.87e-167,"d":"1.87E-167"},{"v":1.8e-166,"d":"1.80E-166"},"down","RASEF","-","GO:0003924;GO:0005509;GO:0005525;GO:0005829;GO:0019003;GO:0042802;GO:0048471;GO:0051260","-","[KOG0078-GTP-binding protein SEC4, small G protein superfamily, and related Ras family GTP-binding proteins[TU], KOG0084-GTPase Rab1/YPT1, small G protein superfamily, and related GTP-binding proteins[TU]]"]
["MYO18A",89.107384,38.601067,-1.206904261,0,0,"down","MYO18A","-","GO:0000139;GO:0000166;GO:0003774;GO:0003779;GO:0005524;GO:0005802;GO:0007030;GO:0016459;GO:0016477;GO:0031032;GO:0042641;GO:0043030;GO:0043066;GO:0043531;GO:0048194;GO:0050714;GO:0051015;GO:0090161;GO:0090164;GO:1903028","-","KOG0161-Myosin class II heavy chain[Z]"]
["LOC100857706",11.7275,5.08026,-1.206921262,{"v":5.23e-26,"d":"5.23E-26"},{"v":1.7e-25,"d":"1.70E-25"},"down","LOC100857706","-","-","-","-"]
["EPB41",34.716923,15.038258,-1.207001628,{"v":5.48e-234,"d":"5.48E-234"},{"v":6.83e-233,"d":"6.83E-233"},"down","EPB41","erythrocyte membrane protein band 4.1","GO:0003779;GO:0005198;GO:0005200;GO:0005516;GO:0005545;GO:0005634;GO:0005737;GO:0005829;GO:0005856;GO:0005886;GO:0005938;GO:0007049;GO:0008022;GO:0008092;GO:0008360;GO:0016020;GO:0030054;GO:0030863;GO:0030866;GO:0031032;GO:0032092;GO:0032991;GO:0047485;GO:0051219;GO:0051301;GO:0099738;GO:1904778","-","[KOG3527-Erythrocyte membrane protein 4.1 and related proteins of the ERM family[R], KOG3530-FERM domain protein EHM2[R]]"]
["KLHL42",10.439354,4.520628,-1.20743733,{"v":3.71e-45,"d":"3.71E-45"},{"v":1.59e-44,"d":"1.59E-44"},"down","KLHL42","-","GO:0000209;GO:0004842;GO:0031463;GO:0032886;GO:0043161","-","KOG4441-Proteins containing BTB/POZ and Kelch domains, involved in regulatory/signal transduction processes[TR]"]
["ZNF367",12.869629,5.572534,-1.207565046,{"v":2.6e-66,"d":"2.60E-66"},{"v":1.36e-65,"d":"1.36E-65"},"down","ZNF367","-","GO:0003676;GO:0003700;GO:0005634;GO:0005654;GO:0006357","-","KOG3623-Homeobox transcription factor SIP1[K]"]
["INPP4B",12.683858,5.481754,-1.210284139,{"v":1.73e-109,"d":"1.73E-109"},{"v":1.23e-108,"d":"1.23E-108"},"down","INPP4B","-","GO:0005737;GO:0007165;GO:0016020;GO:0016021;GO:0016316;GO:0036092","K01109-ko00562 Inositol phosphate metabolism;ko04070 Phosphatidylinositol signaling system","KOG4428-Inositol-polyphosphate 4-phosphatase[T]"]
["ADCY7",6.701178,2.896001,-1.210352629,{"v":2.17e-43,"d":"2.17E-43"},{"v":9.14e-43,"d":"9.14E-43"},"down","ADCY7","-","GO:0000166;GO:0002819;GO:0004016;GO:0004383;GO:0005524;GO:0005886;GO:0006171;GO:0006182;GO:0007165;GO:0008074;GO:0009190;GO:0016020;GO:0016021;GO:0016829;GO:0016849;GO:0035556;GO:0046872;GO:0071285;GO:0071361;GO:1900016","K08047-ko00230 Purine metabolism;ko04015 Rap1 signaling pathway;ko04020 Calcium signaling pathway;ko04072 Phospholipase D signaling pathway;ko04024 cAMP signaling pathway;ko04022 cGMP - PKG signaling pathway;ko04114 Oocyte meiosis;ko04540 Gap junction;ko04611 Platelet activation;ko04062 Chemokine signaling pathway;ko04911 Insulin secretion;ko04923 Regulation of lipolysis in adipocyte;ko04912 GnRH signaling pathway;ko04913 Ovarian Steroidogenesis;ko04915 Estrogen signaling pathway;ko04914 Progesterone-mediated oocyte maturation;ko04921 Oxytocin signaling pathway;ko04918 Thyroid hormone synthesis;ko04916 Melanogenesis;ko04925 Aldosterone synthesis and secretion;ko04261 Adrenergic signaling in cardiomyocytes;ko04270 Vascular smooth muscle contraction;ko04970 Salivary secretion;ko04971 Gastric acid secretion;ko04972 Pancreatic secretion;ko04976 Bile secretion;ko04724 Glutamatergic synapse;ko04727 GABAergic synapse;ko04725 Cholinergic synapse;ko04723 Retrograde endocannabinoid signaling;ko04750 Inflammatory mediator regulation of TRP channels;ko04211 Longevity regulating pathway - mammal;ko04213 Longevity regulating pathway - multiple species;ko04713 Circadian entrainment;ko05200 Pathways in cancer;ko05032 Morphine addiction;ko05414 Dilated cardiomyopathy (DCM);ko05166 HTLV-I infection;ko01522 Endocrine resistance","KOG3619-Adenylate/guanylate cyclase[C]"]
["PTPN13",29.976168,12.948551,-1.211025305,{"v":9.52e-271,"d":"9.52E-271"},{"v":1.33e-269,"d":"1.33E-269"},"down","PTPN13","-","GO:0004725;GO:0005634;GO:0005737;GO:0005886;GO:0006470;GO:0014066;GO:0016311;GO:0016787;GO:0016791;GO:0030027;GO:0035335;GO:0036312","K02374-ko04210 Apoptosis","KOG0792-Protein tyrosine phosphatase PTPMEG, contains FERM domain[T]"]
["LOC112532080",8.817151,3.805535,-1.212213278,{"v":2.3e-06,"d":"2.30E-06"},{"v":4.25e-06,"d":"4.25E-06"},"down","LOC112532080","-","-","-","-"]
["FAM84A",12.133583,5.23659,-1.212306077,{"v":2.59e-116,"d":"2.59E-116"},{"v":1.93e-115,"d":"1.93E-115"},"down","FAM84A","-","-","-","-"]
["ERLIN1",51.469852,22.198418,-1.213270769,{"v":1.49e-211,"d":"1.49E-211"},{"v":1.72e-210,"d":"1.72E-210"},"down","ERLIN1","ER lipid raft associated 1","GO:0005783;GO:0005789;GO:0015485;GO:0030433;GO:0031625;GO:0032933;GO:0032991;GO:0045541;GO:0045717","-","KOG2962-Prohibitin-related membrane protease subunits[R]"]
["CAPN15",27.824368,11.999905,-1.213325934,{"v":2.16e-176,"d":"2.16E-176"},{"v":2.16e-175,"d":"2.16E-175"},"down","CAPN15","-","GO:0004198;GO:0005622;GO:0005737;GO:0006508;GO:0008233;GO:0008234;GO:0016787;GO:0046872","-","KOG0045-Cytosolic Ca2+-dependent cysteine protease (calpain), large subunit (EF-Hand protein superfamily)[OT]"]
["LOC112530196",108.536285,46.796165,-1.213715225,{"v":1.67e-136,"d":"1.67E-136"},{"v":1.39e-135,"d":"1.39E-135"},"down","LOC112530196","-","-","-","-"]
["MIR1306",45.06181,19.422598,-1.214169073,0.010257392,0.014313392,"down","MIR1306","microRNA 1306","-","-","-"]
["ARHGAP32",15.181238,6.537637,-1.215448265,{"v":3.64e-164,"d":"3.64E-164"},{"v":3.46e-163,"d":"3.46E-163"},"down","ARHGAP32","-","-","-","-"]
["LINGO1",17.803791,7.657131,-1.217308626,{"v":6.02e-52,"d":"6.02E-52"},{"v":2.76e-51,"d":"2.76E-51"},"down","LINGO1","leucine rich repeat and Ig domain containing 1","GO:0005154;GO:0005615;GO:0005886;GO:0007165;GO:0007409;GO:0016020;GO:0016021","-","KOG4194-Membrane glycoprotein LIG-1[T]"]
["SRAPL",9.339317,4.009626,-1.219849372,{"v":1.2e-125,"d":"1.20E-125"},{"v":9.44e-125,"d":"9.44E-125"},"down","SRAPL","-","-","-","-"]
["PRDX1",1540.379272,661.018677,-1.220522674,0,0,"down","PRDX1","peroxiredoxin 1","GO:0000302;GO:0004601;GO:0005515;GO:0005634;GO:0005737;GO:0006979;GO:0008283;GO:0008379;GO:0016209;GO:0016491;GO:0019430;GO:0030101;GO:0032872;GO:0034101;GO:0042267;GO:0042744;GO:0042802;GO:0043209;GO:0045454;GO:0051920;GO:0055114;GO:0098869;GO:1901222","K13279-ko04146 Peroxisome","KOG0852-Alkyl hydroperoxide reductase, thiol specific antioxidant and related enzymes[O]"]
["TBC1D1",52.935696,22.692274,-1.22203971,0,0,"down","TBC1D1","TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1","-","-","KOG4436-Predicted GTPase activator NB4S/EVI5 (contains TBC domain)/Calmodulin-binding protein Pollux (contains PTB and TBC domains)[R]"]
["ATP8B1",32.729649,14.025878,-1.222507046,{"v":3.56e-112,"d":"3.56E-112"},{"v":2.58e-111,"d":"2.58E-111"},"down","ATP8B1","ATPase phospholipid transporting 8B1","GO:0000166;GO:0000287;GO:0004012;GO:0005319;GO:0005524;GO:0005783;GO:0005794;GO:0005886;GO:0006855;GO:0007605;GO:0008206;GO:0015247;GO:0015914;GO:0015917;GO:0016020;GO:0016021;GO:0016324;GO:0016787;GO:0021650;GO:0032420;GO:0032534;GO:0045332;GO:0045892;GO:0060119;GO:1901612","-","KOG0206-P-type ATPase[R]"]
["CD9",129.881943,55.655163,-1.222613438,{"v":4.82e-124,"d":"4.82E-124"},{"v":3.75e-123,"d":"3.75E-123"},"down","CD9","CD9 molecule","GO:0005178;GO:0005887;GO:0007155;GO:0007166;GO:0007342;GO:0008285;GO:0009897;GO:0016020;GO:0016021;GO:0030913;GO:0031623;GO:0051271;GO:0070062;GO:0071404;GO:0090331","-","KOG3882-Tetraspanin family integral membrane protein[R]"]
["CPOX",48.899734,20.947462,-1.22305116,{"v":9.75e-93,"d":"9.75E-93"},{"v":6.24e-92,"d":"6.24E-92"},"down","CPOX","-","GO:0004109;GO:0005212;GO:0005739;GO:0005829;GO:0006779;GO:0006783;GO:0016020;GO:0042803;GO:0055114","K00228-ko00860 Porphyrin and chlorophyll metabolism","-"]
["SH2D4A",26.272266,11.253208,-1.223204304,{"v":2.85e-75,"d":"2.85E-75"},{"v":1.6e-74,"d":"1.60E-74"},"down","SH2D4A","-","GO:0005737;GO:0005829;GO:0010923;GO:0019902","-","KOG1264-Phospholipase C[I]"]
["ENHO",19.807423,8.484077,-1.223211574,{"v":3.34e-32,"d":"3.34E-32"},{"v":1.21e-31,"d":"1.21E-31"},"down","ENHO","energy homeostasis associated","GO:0016020;GO:0016021","-","-"]
["TTC7A",17.442226,7.461065,-1.225130688,{"v":3.75e-112,"d":"3.75E-112"},{"v":2.72e-111,"d":"2.72E-111"},"down","TTC7A","tetratricopeptide repeat domain 7A","GO:0005623;GO:0006879;GO:0030097;GO:0072659","-","KOG4162-Predicted calmodulin-binding protein[T]"]
["PDCD6",173.05722,74.015137,-1.225356878,{"v":3.87e-195,"d":"3.87E-195"},{"v":4.15e-194,"d":"4.15E-194"},"down","PDCD6","-","GO:0000139;GO:0000287;GO:0001938;GO:0004198;GO:0005509;GO:0005634;GO:0005737;GO:0005783;GO:0006508;GO:0006886;GO:0006888;GO:0006915;GO:0006919;GO:0010595;GO:0014029;GO:0014032;GO:0016020;GO:0016021;GO:0030127;GO:0030948;GO:0031410;GO:0031463;GO:0032007;GO:0034605;GO:0036324;GO:0042802;GO:0042803;GO:0043280;GO:0043495;GO:0045766;GO:0046983;GO:0048208;GO:0048306;GO:0051592;GO:0051898;GO:0060090;GO:0070971;GO:1902527","-","KOG0037-Ca2+-binding protein, EF-Hand protein superfamily[T]"]
["SFXN2",19.009989,8.127109,-1.225943548,{"v":4.41e-34,"d":"4.41E-34"},{"v":1.64e-33,"d":"1.64E-33"},"down","SFXN2","-","GO:0005739;GO:0006811;GO:0015075;GO:0016020;GO:0016021;GO:0031966;GO:0034220;GO:0055085","-","KOG3767-Sideroflexin[R]"]
["WNK2",61.516781,26.284817,-1.226750322,0,0,"down","WNK2","-","GO:0004672;GO:0004674;GO:0005524;GO:0005737;GO:0005829;GO:0006468;GO:0008285;GO:0016020;GO:0016021;GO:0046777;GO:0050801;GO:0070373;GO:0090263;GO:2000651","-","-"]
["RREB1",8.012941,3.422802,-1.227154015,{"v":7.78e-78,"d":"7.78E-78"},{"v":4.46e-77,"d":"4.46E-77"},"down","RREB1","ras responsive element binding protein 1","GO:0000122;GO:0000977;GO:0000978;GO:0001228;GO:0001650;GO:0003676;GO:0003677;GO:0003700;GO:0005634;GO:0006351;GO:0006355;GO:0006366;GO:0007165;GO:0007275;GO:0010634;GO:0016607;GO:0033601;GO:0043565;GO:0044212;GO:0045892;GO:0045944;GO:0046872;GO:1900026;GO:1903691;GO:2000394","-","KOG1074-Transcriptional repressor SALM[K]"]
["MSRB3",123.669983,52.804855,-1.227752888,0,0,"down","MSRB3","methionine sulfoxide reductase B3","GO:0005739;GO:0005783;GO:0006979;GO:0008270;GO:0016671;GO:0030091;GO:0033743;GO:0055114","-","KOG0856-Predicted pilin-like transcription factor[O]"]
["IQGAP2",50.229755,21.443954,-1.227971293,{"v":5.23e-287,"d":"5.23E-287"},{"v":7.61e-286,"d":"7.61E-286"},"down","IQGAP2","IQ motif containing GTPase activating protein 2","GO:0005516;GO:0005547;GO:0005737;GO:0005902;GO:0007165;GO:0009986;GO:0017048;GO:0030027;GO:0030175;GO:0031941;GO:0034314;GO:0043087;GO:0048365;GO:0051015;GO:0070493;GO:0071933","K05767-ko04810 Regulation of actin cytoskeleton","KOG2128-Ras GTPase-activating protein family - IQGAP[T]"]
["LOC107050599",298.424438,127.307014,-1.229053776,{"v":3.42e-197,"d":"3.42E-197"},{"v":3.68e-196,"d":"3.68E-196"},"down","LOC107050599","-","-","-","-"]
["CLDN25",13.876051,5.909043,-1.231600646,{"v":1.14e-27,"d":"1.14E-27"},{"v":3.83e-27,"d":"3.83E-27"},"down","CLDN25","-","GO:0005198;GO:0005886;GO:0005923;GO:0016020;GO:0016021;GO:0030054","K06087-ko04514 Cell adhesion molecules (CAMs);ko04530 Tight junction;ko04670 Leukocyte transendothelial migration;ko05160 Hepatitis C","-"]
["RAB31",32.743328,13.941342,-1.231831521,{"v":2.79e-178,"d":"2.79E-178"},{"v":2.8e-177,"d":"2.80E-177"},"down","RAB31","-","GO:0003924;GO:0005525;GO:0005769;GO:0019003;GO:0031623;GO:0032588;GO:0032869;GO:0043001;GO:0045055;GO:0045335;GO:0090382","K07891-ko04144 Endocytosis","KOG0092-GTPase Rab5/YPT51 and related small G protein superfamily GTPases[U]"]
["C12orf75",49.427456,21.027225,-1.233054186,{"v":7.44e-80,"d":"7.44E-80"},{"v":4.33e-79,"d":"4.33E-79"},"down","C12orf75","chromosome 12 open reading frame 75","-","-","-"]
["ANXA2",3317.710449,1410.18103,-1.234307603,0,0,"down","ANXA2","annexin A2","GO:0001525;GO:0001765;GO:0001921;GO:0002020;GO:0003417;GO:0004859;GO:0005262;GO:0005509;GO:0005544;GO:0005546;GO:0005576;GO:0005604;GO:0005737;GO:0005765;GO:0005768;GO:0005769;GO:0005811;GO:0005829;GO:0005886;GO:0006900;GO:0008092;GO:0009986;GO:0010755;GO:0016323;GO:0019834;GO:0019897;GO:0030199;GO:0030282;GO:0030496;GO:0031012;GO:0031340;GO:0031902;GO:0031982;GO:0032332;GO:0032804;GO:0032907;GO:0032991;GO:0034704;GO:0035749;GO:0036035;GO:0036366;GO:0042383;GO:0042730;GO:0042802;GO:0043086;GO:0043220;GO:0044090;GO:0044147;GO:0044548;GO:0045121;GO:0046790;GO:0048306;GO:0051099;GO:0051290;GO:0051480;GO:0051928;GO:0052362;GO:0052405;GO:0055074;GO:0060956;GO:0070062;GO:0070588;GO:0098772;GO:0099511;GO:1905581;GO:1905597;GO:1905599;GO:1905602;GO:1990667;GO:0001525;GO:0001765;GO:0001921;GO:0002020;GO:0004859;GO:0005509;GO:0005544;GO:0005546;GO:0005737;GO:0005765;GO:0005768;GO:0005769;GO:0005811;GO:0005829;GO:0005886;GO:0006900;GO:0008092;GO:0009986;GO:0016323;GO:0019834;GO:0019897;GO:0030199;GO:0030496;GO:0031340;GO:0031902;GO:0032804;GO:0035749;GO:0036035;GO:0042383;GO:0042730;GO:0042802;GO:0043086;GO:0043220;GO:0044090;GO:0044147;GO:0044548;GO:0045121;GO:0048306;GO:0051099;GO:0051290;GO:0052362;GO:0052405;GO:0070062;GO:0098772;GO:1905581;GO:1905597;GO:1905599;GO:1905602;GO:1990667","-","KOG0819-Annexin[U]"]
["FOSL2",30.658892,13.026608,-1.23484409,{"v":5.74e-148,"d":"5.74E-148"},{"v":5.05e-147,"d":"5.05E-147"},"down","FOSL2","FOS like 2, AP-1 transcription factor subunit","GO:0000977;GO:0001228;GO:0003334;GO:0003677;GO:0003682;GO:0003700;GO:0005634;GO:0005654;GO:0006355;GO:0006357;GO:0006366;GO:0045893;GO:0045944;GO:0048146;GO:0000977;GO:0001228;GO:0003334;GO:0003677;GO:0003682;GO:0003700;GO:0005634;GO:0005654;GO:0006355;GO:0006357;GO:0006366;GO:0045893;GO:0045944;GO:0048146","-","KOG1414-Transcriptional activator FOSB/c-Fos and related bZIP transcription factors[K]"]
["INPP4A",59.400135,25.225586,-1.235578426,0,0,"down","INPP4A","-","GO:0016316;GO:0036092","K01109-ko00562 Inositol phosphate metabolism;ko04070 Phosphatidylinositol signaling system","KOG4428-Inositol-polyphosphate 4-phosphatase[T]"]
["RARB",43.933674,18.648415,-1.236274136,{"v":3.41e-111,"d":"3.41E-111"},{"v":2.46e-110,"d":"2.46E-110"},"down","RARB","retinoic acid receptor beta","GO:0003677;GO:0003700;GO:0003707;GO:0005634;GO:0006351;GO:0006355;GO:0008270;GO:0043401;GO:0043565;GO:0046872;GO:0048384;GO:0000122;GO:0000977;GO:0001657;GO:0002068;GO:0003148;GO:0003406;GO:0003417;GO:0003677;GO:0003700;GO:0003707;GO:0005623;GO:0005634;GO:0005654;GO:0006351;GO:0006355;GO:0008270;GO:0008284;GO:0008285;GO:0021756;GO:0022008;GO:0032331;GO:0032526;GO:0035108;GO:0035116;GO:0035264;GO:0043065;GO:0043066;GO:0043068;GO:0043401;GO:0043565;GO:0045944;GO:0046872;GO:0048048;GO:0048384;GO:0048471;GO:0048566;GO:0055012;GO:0060041;GO:0060348;GO:0061037;GO:0070660;GO:0071729","-","KOG4217-Nuclear receptors of the nerve growth factor-induced protein B type[K]"]
["KCNS2",11.653204,4.939523,-1.238283037,{"v":5.44e-188,"d":"5.44E-188"},{"v":5.68e-187,"d":"5.68E-187"},"down","KCNS2","-","GO:0005216;GO:0005244;GO:0005249;GO:0005267;GO:0005886;GO:0006811;GO:0006813;GO:0008076;GO:0016020;GO:0016021;GO:0034765;GO:0048471;GO:0051260;GO:0055085;GO:0071805;GO:1902259","-","KOG3713-Voltage-gated K+ channel KCNB/KCNC[P]"]
["EHD4",38.45668,16.267761,-1.241218518,{"v":2.13e-242,"d":"2.13E-242"},{"v":2.73e-241,"d":"2.73E-241"},"down","EHD4","-","GO:0005509;GO:0005525;GO:0005783;GO:0032456;GO:0048471;GO:0051260;GO:0055038","K12477-ko04144 Endocytosis","KOG1954-Endocytosis/signaling protein EHD1[TU]"]
["CORO1C",87.190056,36.881939,-1.241249101,0,0,"down","CORO1C","coronin, actin binding protein, 1C","GO:0001755;GO:0001932;GO:0001933;GO:0005856;GO:0010632;GO:0010633;GO:0010762;GO:0015629;GO:0016328;GO:0016600;GO:0030027;GO:0030036;GO:0031982;GO:0044387;GO:0045184;GO:0048365;GO:0051015;GO:0051893;GO:0051895;GO:0090630;GO:1900024;GO:1900025;GO:1900027;GO:2000394;GO:0015629;GO:0030036;GO:0051015","-","KOG0303-Actin-binding protein Coronin, contains WD40 repeats[Z]"]
["FER",13.86544,5.862918,-1.241802615,{"v":1.16e-160,"d":"1.16E-160"},{"v":1.08e-159,"d":"1.08E-159"},"down","FER","-","GO:0000226;GO:0000278;GO:0000790;GO:0001932;GO:0004672;GO:0004713;GO:0004715;GO:0005102;GO:0005154;GO:0005634;GO:0005737;GO:0005829;GO:0006468;GO:0006935;GO:0007155;GO:0007165;GO:0007173;GO:0007260;GO:0008157;GO:0008283;GO:0008284;GO:0008289;GO:0010591;GO:0010762;GO:0015629;GO:0015630;GO:0016477;GO:0018108;GO:0019221;GO:0030027;GO:0030054;GO:0030154;GO:0030335;GO:0030838;GO:0031234;GO:0031532;GO:0032496;GO:0032869;GO:0033007;GO:0034446;GO:0034614;GO:0035426;GO:0036006;GO:0036119;GO:0038028;GO:0038083;GO:0038095;GO:0038109;GO:0042058;GO:0042127;GO:0043304;GO:0044331;GO:0045087;GO:0046777;GO:0048008;GO:0050904;GO:0051092;GO:0070102","-","KOG0194-Protein tyrosine kinase[T]"]
["TSTA3",58.95118,24.878969,-1.244593991,{"v":9.39e-102,"d":"9.39E-102"},{"v":6.35e-101,"d":"6.35E-101"},"down","TSTA3","tissue specific transplantation antigen P35B","GO:0003824;GO:0009226;GO:0016491;GO:0019673;GO:0042351;GO:0042802;GO:0047918;GO:0050577;GO:0050662;GO:0055114","K02377-ko00051 Fructose and mannose metabolism;ko00520 Amino sugar and nucleotide sugar metabolism","KOG1431-GDP-L-fucose synthetase[GO]"]
["RAB11FIP1",39.447651,16.639257,-1.245348381,{"v":1.43e-265,"d":"1.43E-265"},{"v":1.96e-264,"d":"1.96E-264"},"down","RAB11FIP1","-","-","K12484-ko04144 Endocytosis","-"]
["CCND1",16.802788,7.085056,-1.245849471,{"v":2.3e-25,"d":"2.30E-25"},{"v":7.39e-25,"d":"7.39E-25"},"down","CCND1","cyclin D1","GO:0000082;GO:0000122;GO:0000307;GO:0000320;GO:0001934;GO:0003714;GO:0004672;GO:0005622;GO:0005634;GO:0005654;GO:0005737;GO:0005923;GO:0006351;GO:0006355;GO:0006468;GO:0006974;GO:0007049;GO:0008134;GO:0010971;GO:0016055;GO:0016301;GO:0016538;GO:0017053;GO:0019899;GO:0019901;GO:0030857;GO:0030968;GO:0031571;GO:0033601;GO:0042493;GO:0042826;GO:0044321;GO:0045444;GO:0045737;GO:0050679;GO:0051301;GO:0051726;GO:0070064;GO:0070141;GO:0071157;GO:0071310;GO:0097421;GO:2000045","K04503-ko04310 Wnt signaling pathway;ko04340 Hedgehog signaling pathway;ko04390 Hippo signaling pathway;ko04630 Jak-STAT signaling pathway;ko04068 FoxO signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04152 AMPK signaling pathway;ko04110 Cell cycle;ko04115 p53 signaling pathway;ko04510 Focal adhesion;ko04917 Prolactin signaling pathway;ko04921 Oxytocin signaling pathway;ko04919 Thyroid hormone signaling pathway;ko05200 Pathways in cancer;ko05206 MicroRNAs in cancer;ko05205 Proteoglycans in cancer;ko05203 Viral carcinogenesis;ko05210 Colorectal cancer;ko05212 Pancreatic cancer;ko05214 Glioma;ko05216 Thyroid cancer;ko05221 Acute myeloid leukemia;ko05220 Chronic myeloid leukemia;ko05218 Melanoma;ko05219 Bladder cancer;ko05215 Prostate cancer;ko05213 Endometrial cancer;ko05224 Breast cancer;ko05222 Small cell lung cancer;ko05223 Non-small cell lung cancer;ko05416 Viral myocarditis;ko04933 AGE-RAGE signaling pathway in diabetic complications;ko05166 HTLV-I infection;ko05162 Measles;ko05161 Hepatitis B;ko01522 Endocrine resistance","KOG0656-G1/S-specific cyclin D[D]"]
["CCNA2",11.5683,4.872376,-1.247479496,{"v":1.09e-26,"d":"1.09E-26"},{"v":3.59e-26,"d":"3.59E-26"},"down","CCNA2","cyclin A2","GO:0000086;GO:0000307;GO:0005634;GO:0005654;GO:0005737;GO:0007049;GO:0044843;GO:0051301;GO:0000086;GO:0000307;GO:0001939;GO:0001940;GO:0005634;GO:0005654;GO:0005737;GO:0005829;GO:0007265;GO:0016572;GO:0019901;GO:0019904;GO:0044843;GO:0045893;GO:0051726;GO:0097124;GO:0097472","K06627-ko04152 AMPK signaling pathway;ko04110 Cell cycle;ko04914 Progesterone-mediated oocyte maturation;ko05203 Viral carcinogenesis;ko05161 Hepatitis B;ko05169 Epstein-Barr virus infection","KOG0654-G2/Mitotic-specific cyclin A[D]"]
["LOC112532901",7.147618,3.009938,-1.247728762,{"v":9.51e-18,"d":"9.51E-18"},{"v":2.62e-17,"d":"2.62E-17"},"down","LOC112532901","-","-","-","-"]
["PALMD",69.160843,29.104437,-1.248716344,{"v":6.11e-61,"d":"6.11E-61"},{"v":3.05e-60,"d":"3.05E-60"},"down","PALMD","palmdelphin","GO:0008360;GO:0016020","-","-"]
["YES1",63.701546,26.801878,-1.248994293,{"v":4.9e-131,"d":"4.90E-131"},{"v":3.97e-130,"d":"3.97E-130"},"down","YES1","YES proto-oncogene 1, Src family tyrosine kinase","GO:0000166;GO:0004672;GO:0004713;GO:0004715;GO:0005524;GO:0006468;GO:0016301;GO:0016310;GO:0016740;GO:0018108;GO:0000166;GO:0001784;GO:0004672;GO:0004713;GO:0004715;GO:0005102;GO:0005524;GO:0005737;GO:0005794;GO:0005815;GO:0005829;GO:0005856;GO:0005884;GO:0005886;GO:0006468;GO:0007169;GO:0010827;GO:0016020;GO:0016301;GO:0016310;GO:0016477;GO:0016740;GO:0019899;GO:0030154;GO:0031234;GO:0036120;GO:0038083;GO:0042127;GO:0044325;GO:0045087;GO:0045944;GO:0050731;GO:0071300;GO:0071560","K05705-ko04520 Adherens junction;ko04530 Tight junction","KOG0197-Tyrosine kinases[T]"]
["COL1A2",412.283417,173.423645,-1.249335821,0,0,"down","COL1A2","collagen, type I, alpha 2","GO:0001501;GO:0001568;GO:0002020;GO:0005201;GO:0005576;GO:0005581;GO:0005583;GO:0005584;GO:0005615;GO:0005783;GO:0007179;GO:0007266;GO:0008217;GO:0030199;GO:0030674;GO:0042802;GO:0043589;GO:0046332;GO:0046872;GO:0048407;GO:0070208;GO:0071230","K06236-ko04151 PI3K-Akt signaling pathway;ko04512 ECM-receptor interaction;ko04510 Focal adhesion;ko04611 Platelet activation;ko04974 Protein digestion and absorption;ko04933 AGE-RAGE signaling pathway in diabetic complications;ko05146 Amoebiasis","-"]
["TRIM24",17.8011,7.482038,-1.250463196,{"v":1.37e-89,"d":"1.37E-89"},{"v":8.57e-89,"d":"8.57E-89"},"down","TRIM24","-","GO:0002039;GO:0003682;GO:0003713;GO:0004672;GO:0004842;GO:0005622;GO:0005634;GO:0005654;GO:0005719;GO:0005726;GO:0005737;GO:0006468;GO:0008270;GO:0008285;GO:0010628;GO:0016567;GO:0016922;GO:0030163;GO:0031647;GO:0034056;GO:0042981;GO:0043565;GO:0045892;GO:0045893;GO:0046777;GO:0046872;GO:0055074;GO:0061630;GO:0070562;GO:0070577;GO:0071391;GO:1901796","-","KOG1245-Chromatin remodeling complex WSTF-ISWI, large subunit (contains heterochromatin localization, PHD and BROMO domains)[B]"]
["PTPRA",123.888763,52.052582,-1.251003704,0,0,"down","PTPRA","protein tyrosine phosphatase, receptor type A","GO:0004721;GO:0004725;GO:0005515;GO:0006468;GO:0006470;GO:0008286;GO:0016020;GO:0016021;GO:0016311;GO:0016787;GO:0016791;GO:0035335;GO:0043235;GO:0050804;GO:0098685;GO:0099699","-","KOG4228-Protein tyrosine phosphatase[T]"]
["TMEM248",146.023926,61.300018,-1.252245371,0,0,"down","TMEM248","-","GO:0016020;GO:0016021","-","-"]
["CEP170B",25.887903,10.863355,-1.252808378,0,0,"down","CEP170B","-","-","-","-"]
["ST5",28.460972,11.936979,-1.253547167,{"v":1.4e-150,"d":"1.40E-150"},{"v":1.25e-149,"d":"1.25E-149"},"down","ST5","-","-","-","KOG3569-RAS signaling inhibitor ST5[T]"]
["KLHL25",18.590963,7.780506,-1.256665615,{"v":6.19e-69,"d":"6.19E-69"},{"v":3.32e-68,"d":"3.32E-68"},"down","KLHL25","-","GO:0005737;GO:0006446;GO:0006511;GO:0016567;GO:0031463","-","KOG4441-Proteins containing BTB/POZ and Kelch domains, involved in regulatory/signal transduction processes[TR]"]
["TPM4",16.776634,7.014652,-1.25800985,{"v":2.42e-68,"d":"2.42E-68"},{"v":1.29e-67,"d":"1.29E-67"},"down","TPM4","-","GO:0002102;GO:0005737;GO:0005862;GO:0005884;GO:0006936;GO:0007015;GO:0008307;GO:0030863;GO:0051015","K10375-ko04260 Cardiac muscle contraction;ko04261 Adrenergic signaling in cardiomyocytes;ko05410 Hypertrophic cardiomyopathy (HCM);ko05414 Dilated cardiomyopathy (DCM)","KOG1003-Actin filament-coating protein tropomyosin[Z]"]
["ADK",31.303883,13.086126,-1.258303556,{"v":2.07e-75,"d":"2.07E-75"},{"v":1.17e-74,"d":"1.17E-74"},"down","ADK","adenosine kinase","GO:0004001;GO:0006166;GO:0006167;GO:0016773;GO:0004001;GO:0005634;GO:0005654;GO:0005829;GO:0006166;GO:0006167;GO:0006175;GO:0016773","K00856-ko00230 Purine metabolism","KOG2854-Possible pfkB family carbohydrate kinase[G]"]
["ELMOD2",26.160406,10.934323,-1.258521033,{"v":2.13e-48,"d":"2.13E-48"},{"v":9.42e-48,"d":"9.42E-48"},"down","ELMOD2","ELMO domain containing 2","GO:0005096;GO:0043547;GO:0050688","-","KOG2998-Uncharacterized conserved protein[S]"]
["LOC112529976",5.365446,2.242409,-1.258648659,{"v":5.73e-10,"d":"5.73E-10"},{"v":1.25e-09,"d":"1.25E-09"},"down","LOC112529976","-","-","-","-"]
["WASL",79.099922,33.05217,-1.258931279,0,0,"down","WASL","Wiskott-Aldrich syndrome-like","GO:0003779;GO:0007015;GO:2000601","K05747-ko04144 Endocytosis;ko04810 Regulation of actin cytoskeleton;ko04520 Adherens junction;ko04666 Fc gamma R-mediated phagocytosis;ko04062 Chemokine signaling pathway;ko05231 Choline metabolism in cancer;ko05130 Pathogenic Escherichia coli infection;ko05132 Salmonella infection;ko05131 Shigellosis;ko05100 Bacterial invasion of epithelial cells","-"]
["NASP",24.933035,10.417881,-1.258996644,{"v":3.8e-86,"d":"3.80E-86"},{"v":2.32e-85,"d":"2.32E-85"},"down","NASP","-","GO:0016020;GO:0016021","-","KOG4563-Cell cycle-regulated histone H1-binding protein[BD]"]
["RENBP",8.239628,3.437675,-1.261146047,{"v":3.07e-08,"d":"3.07E-08"},{"v":6.21e-08,"d":"6.21E-08"},"down","RENBP","-","-","K01787-ko00520 Amino sugar and nucleotide sugar metabolism","-"]
["GBA2",25.936357,10.818715,-1.261446702,{"v":8.93e-96,"d":"8.93E-96"},{"v":5.83e-95,"d":"5.83E-95"},"down","GBA2","-","GO:0003824;GO:0004348;GO:0004553;GO:0006629;GO:0006680;GO:0008152;GO:0008206;GO:0008422;GO:0016020;GO:0016021;GO:0016139;GO:0016787;GO:0016798;GO:0021954","K17108-ko00600 Sphingolipid metabolism;ko00511 Other glycan degradation","KOG2119-Predicted bile acid beta-glucosidase[G]"]
["CPNE2",49.628643,20.698158,-1.261670624,{"v":1.03e-128,"d":"1.03E-128"},{"v":8.22e-128,"d":"8.22E-128"},"down","CPNE2","copine 2","GO:0005634;GO:0005737;GO:0005886;GO:0071277","-","KOG1327-Copine[T]"]
["LOC107051323",25.277498,10.537673,-1.262297354,{"v":6.23e-37,"d":"6.23E-37"},{"v":2.4e-36,"d":"2.40E-36"},"down","LOC107051323","-","-","-","-"]
["PQLC3",57.777424,24.021862,-1.2661579,{"v":2.73e-174,"d":"2.73E-174"},{"v":2.7e-173,"d":"2.70E-173"},"down","PQLC3","-","GO:0006488;GO:0016020;GO:0016021","-","KOG3211-Predicted endoplasmic reticulum membrane protein Lec35/MPDU1 involved in monosaccharide-P-dolichol utilization[R]"]
["PTPRK",29.851435,12.404889,-1.26689146,{"v":3.88e-208,"d":"3.88E-208"},{"v":4.42e-207,"d":"4.42E-207"},"down","PTPRK","-","GO:0001750;GO:0004721;GO:0004725;GO:0005886;GO:0005911;GO:0006470;GO:0007155;GO:0007165;GO:0007179;GO:0008013;GO:0008285;GO:0009986;GO:0010839;GO:0016020;GO:0016021;GO:0016311;GO:0016477;GO:0016787;GO:0016791;GO:0019901;GO:0030054;GO:0030336;GO:0030424;GO:0030425;GO:0031256;GO:0034394;GO:0034614;GO:0034644;GO:0035335;GO:0043025;GO:0043231;GO:0045295;GO:0045786;GO:0045892;GO:0048041","-","KOG4228-Protein tyrosine phosphatase[T]"]
["RPS6KL1",16.284222,6.76641,-1.267012292,{"v":1.2e-49,"d":"1.20E-49"},{"v":5.41e-49,"d":"5.41E-49"},"down","RPS6KL1","-","-","-","KOG0603-Ribosomal protein S6 kinase[T]"]
["COBLL1",55.721245,23.14382,-1.267600485,{"v":9.28e-284,"d":"9.28E-284"},{"v":1.34e-282,"d":"1.34E-282"},"down","COBLL1","-","GO:0003785;GO:0030041;GO:0051639","-","-"]
["TNS1",139.924667,58.105495,-1.267903804,0,0,"down","TNS1","tensin 1","GO:0005925;GO:0007044;GO:0010761;GO:0030055","-","-"]
["CUX1",62.600742,25.941465,-1.270919802,{"v":4.34e-182,"d":"4.34E-182"},{"v":4.44e-181,"d":"4.44E-181"},"down","CUX1","cut like homeobox 1","GO:0000122;GO:0000139;GO:0000977;GO:0005634;GO:0006891;GO:0007275;GO:0016020;GO:0016021;GO:0030173;GO:0048193","-","KOG0963-Transcription factor/CCAAT displacement protein CDP1[K]"]
["DCAKD",8.05148,3.335799,-1.271221638,{"v":6.72e-14,"d":"6.72E-14"},{"v":1.68e-13,"d":"1.68E-13"},"down","DCAKD","-","GO:0004140;GO:0005524;GO:0015937;GO:0016020;GO:0016021;GO:0016310","-","KOG3220-Similar to bacterial dephospho-CoA kinase[H]"]
["RAP2B",21.811522,9.036113,-1.271316227,{"v":5.08e-97,"d":"5.08E-97"},{"v":3.35e-96,"d":"3.35E-96"},"down","RAP2B","-","GO:0000166;GO:0003924;GO:0005525;GO:0005829;GO:0005886;GO:0005923;GO:0007165;GO:0016020;GO:0019003;GO:0019904;GO:0030168;GO:0030336;GO:0031954;GO:0032486;GO:0044291;GO:0045121;GO:0055037;GO:0055038;GO:0061097;GO:0070062;GO:0070527","-","KOG0395-Ras-related GTPase[R]"]
["PRC1",8.839968,3.661166,-1.271737959,{"v":1.09e-31,"d":"1.09E-31"},{"v":3.9e-31,"d":"3.90E-31"},"down","PRC1","protein regulator of cytokinesis 1","GO:0000226;GO:0000910;GO:0001578;GO:0005856;GO:0008017","-","-"]
["LOC100858796",50.079922,20.726048,-1.272787263,{"v":6.36e-176,"d":"6.36E-176"},{"v":6.34e-175,"d":"6.34E-175"},"down","LOC100858796","-","GO:0001932;GO:0005092;GO:0005634;GO:0005737;GO:0005739;GO:0006111;GO:0006635;GO:0007005;GO:0009749;GO:0016239;GO:0016684;GO:0030308;GO:0030330;GO:0031588;GO:0031932;GO:0032042;GO:0032542;GO:0032868;GO:0034198;GO:0034599;GO:0036091;GO:0042149;GO:0042593;GO:0043491;GO:0046323;GO:0061700;GO:0070328;GO:0070728;GO:0071230;GO:0071233;GO:0072593;GO:0098869;GO:1900182;GO:1901031;GO:1902010;GO:1904262;GO:1904504;GO:1990253;GO:1990316;GO:2000479","K20394-ko04150 mTOR signaling pathway;ko04115 p53 signaling pathway;ko04211 Longevity regulating pathway - mammal","-"]
["CTNND1",165.853119,68.5905,-1.273825466,0,0,"down","CTNND1","-","-","K05690-ko04015 Rap1 signaling pathway;ko04520 Adherens junction;ko04670 Leukocyte transendothelial migration","KOG1048-Neural adherens junction protein Plakophilin and related Armadillo repeat proteins[TW]"]
["ADAP1",23.890358,9.874253,-1.274684957,{"v":7.9e-87,"d":"7.90E-87"},{"v":4.85e-86,"d":"4.85E-86"},"down","ADAP1","-","GO:0005096;GO:0005634;GO:0005737;GO:0005829;GO:0005886;GO:0043087;GO:0043547;GO:1902936","-","-"]
["EPHA1",27.409546,11.314145,-1.276550867,{"v":2.36e-127,"d":"2.36E-127"},{"v":1.87e-126,"d":"1.87E-126"},"down","EPHA1","EPH receptor A1","GO:0000166;GO:0001954;GO:0004672;GO:0004713;GO:0005003;GO:0005005;GO:0005524;GO:0005887;GO:0006468;GO:0006469;GO:0007166;GO:0007169;GO:0008284;GO:0016020;GO:0016021;GO:0016301;GO:0016310;GO:0016740;GO:0018108;GO:0019901;GO:0030335;GO:0030336;GO:0034446;GO:0043087;GO:0045766;GO:0046777;GO:0048013;GO:0051496;GO:0090630","-","KOG0196-Tyrosine kinase, EPH (ephrin) receptor family[T]"]
["SNRK",28.794813,11.855077,-1.28030392,{"v":4.71e-52,"d":"4.71E-52"},{"v":2.16e-51,"d":"2.16E-51"},"down","SNRK","SNF related kinase","GO:0000287;GO:0004672;GO:0004674;GO:0005524;GO:0006468","-","KOG4717-Serine/threonine protein kinase[T]"]
["FRMD4A",19.3127,7.948195,-1.2808507,{"v":1.79e-158,"d":"1.79E-158"},{"v":1.65e-157,"d":"1.65E-157"},"down","FRMD4A","-","-","-","-"]
["IGFBP4",177.409683,73.009163,-1.280935308,0,0,"down","IGFBP4","insulin like growth factor binding protein 4","GO:0001558;GO:0005520;GO:0005576;GO:0005615;GO:0010906;GO:0040008;GO:0043410;GO:0043568;GO:0044342","-","-"]
["TPK1",13.081169,5.382252,-1.281209628,{"v":2e-53,"d":"2.00E-53"},{"v":9.32e-53,"d":"9.32E-53"},"down","TPK1","-","GO:0000166;GO:0004788;GO:0005524;GO:0006772;GO:0009229;GO:0016301;GO:0016310;GO:0016740;GO:0030975","K00949-ko00730 Thiamine metabolism","KOG3153-Thiamine pyrophosphokinase[H]"]
["AFAP1L2",31.542767,12.971138,-1.282004165,{"v":7.95e-154,"d":"7.95E-154"},{"v":7.18e-153,"d":"7.18E-153"},"down","AFAP1L2","-","GO:0005737;GO:0005829;GO:0005886;GO:0006954;GO:0007346;GO:0009966;GO:0017124;GO:0030296;GO:0032675;GO:0032757;GO:0035591;GO:0042169;GO:0045742;GO:0045893;GO:0061098","-","-"]
["STON1",22.99123,9.439977,-1.284228401,{"v":1.95e-162,"d":"1.95E-162"},{"v":1.83e-161,"d":"1.83E-161"},"down","STON1","stonin 1","GO:0006897;GO:0030100","-","KOG2677-Stoned B synaptic vesicle biogenesis protein[U]"]
["SEPT9",140.974045,57.838531,-1.285326754,0,0,"down","SEPT9","septin 9","GO:0000166;GO:0001725;GO:0005525;GO:0005874;GO:0005930;GO:0015629;GO:0031105;GO:0048471;GO:0051291;GO:0097730;GO:1902857","-","KOG1547-Septin CDC10 and related P-loop GTPases[DTZ]"]
["ETNPPL",35.86491,14.690918,-1.287648461,{"v":2.6e-123,"d":"2.60E-123"},{"v":2.01e-122,"d":"2.01E-122"},"down","ETNPPL","-","GO:0003824;GO:0008483;GO:0030170;GO:0050459","K14286-ko00564 Glycerophospholipid metabolism","KOG1403-Predicted alanine-glyoxylate aminotransferase[R]"]
["GPR153",5.812777,2.379953,-1.288294479,{"v":2.66e-17,"d":"2.66E-17"},{"v":7.26e-17,"d":"7.26E-17"},"down","GPR153","-","GO:0004930;GO:0007186;GO:0016020;GO:0016021","-","-"]
["LOC107056441",59.609249,24.397501,-1.288802815,{"v":2.05e-153,"d":"2.05E-153"},{"v":1.85e-152,"d":"1.85E-152"},"down","LOC107056441","-","-","-","-"]
["DNAJC5",9.561424,3.907909,-1.290828624,{"v":5.29e-19,"d":"5.29E-19"},{"v":1.5e-18,"d":"1.50E-18"},"down","DNAJC5","DnaJ heat shock protein family (Hsp40) member C5","GO:0005886;GO:0008021;GO:0031594;GO:0043524;GO:0061077;GO:0098693;GO:0098793","K09525-ko04141 Protein processing in endoplasmic reticulum","KOG0716-Molecular chaperone (DnaJ superfamily)[O]"]
["MOV10",18.144855,7.415055,-1.291031229,{"v":4.03e-75,"d":"4.03E-75"},{"v":2.26e-74,"d":"2.26E-74"},"down","MOV10","Mov10 RISC complex RNA helicase","GO:0000932;GO:0005829;GO:0035195;GO:0035279;GO:0000166;GO:0000932;GO:0003723;GO:0004386;GO:0005524;GO:0005737;GO:0016787;GO:0031047;GO:0035195;GO:0035279","-","-"]
["WNT5A",125.848717,51.40118,-1.291817124,0,0,"down","WNT5A","Wnt family member 5A","GO:0000187;GO:0001667;GO:0001736;GO:0001756;GO:0001819;GO:0001837;GO:0001843;GO:0001934;GO:0001938;GO:0001947;GO:0002009;GO:0002053;GO:0002088;GO:0002741;GO:0003323;GO:0003344;GO:0003401;GO:0003402;GO:0003408;GO:0003700;GO:0005102;GO:0005109;GO:0005115;GO:0005125;GO:0005576;GO:0005615;GO:0005622;GO:0006468;GO:0007223;GO:0007254;GO:0007257;GO:0007275;GO:0007368;GO:0007409;GO:0007411;GO:0007442;GO:0007494;GO:0008284;GO:0008584;GO:0008595;GO:0009952;GO:0009986;GO:0010033;GO:0010469;GO:0010595;GO:0010628;GO:0010800;GO:0010820;GO:0010976;GO:0016055;GO:0016477;GO:0019904;GO:0021891;GO:0021915;GO:0022008;GO:0030182;GO:0030216;GO:0030324;GO:0030326;GO:0030514;GO:0030901;GO:0031012;GO:0032092;GO:0032148;GO:0032729;GO:0032755;GO:0032880;GO:0033138;GO:0034613;GO:0035108;GO:0035567;GO:0036342;GO:0036517;GO:0036518;GO:0038031;GO:0040037;GO:0042060;GO:0042472;GO:0042733;GO:0043032;GO:0043066;GO:0043122;GO:0043507;GO:0043547;GO:0044212;GO:0045080;GO:0045165;GO:0045198;GO:0045599;GO:0045662;GO:0045732;GO:0045745;GO:0045766;GO:0045778;GO:0045807;GO:0045836;GO:0045860;GO:0045892;GO:0045893;GO:0045944;GO:0046330;GO:0046546;GO:0048022;GO:0048146;GO:0048341;GO:0048546;GO:0048570;GO:0048706;GO:0048806;GO:0048812;GO:0048843;GO:0048850;GO:0050679;GO:0050680;GO:0050718;GO:0050729;GO:0050807;GO:0050919;GO:0051092;GO:0051885;GO:0051964;GO:0060026;GO:0060028;GO:0060029;GO:0060065;GO:0060067;GO:0060068;GO:0060070;GO:0060071;GO:0060324;GO:0060340;GO:0060606;GO:0060638;GO:0060686;GO:0060760;GO:0060762;GO:0060775;GO:0060809;GO:0060907;GO:0061036;GO:0061053;GO:0061347;GO:0061348;GO:0061349;GO:0061350;GO:0061354;GO:0062009;GO:0070245;GO:0071219;GO:0071222;GO:0071277;GO:0071346;GO:0071425;GO:0071542;GO:0071560;GO:0072201;GO:0090009;GO:0090037;GO:0090090;GO:0090103;GO:0090179;GO:0090630;GO:0097325;GO:0098794;GO:0098978;GO:0099175;GO:0099566;GO:0150012;GO:1900020;GO:1901216;GO:1902379;GO:1903827;GO:1904469;GO:1904934;GO:1904938;GO:1904948;GO:1904953;GO:2000049;GO:2000052;GO:2000484","K00444-ko04310 Wnt signaling pathway;ko04390 Hippo signaling pathway;ko04150 mTOR signaling pathway;ko04550 Signaling pathways regulating pluripotency of stem cells;ko04916 Melanogenesis;ko04360 Axon guidance;ko05200 Pathways in cancer;ko05205 Proteoglycans in cancer;ko05217 Basal cell carcinoma;ko05224 Breast cancer;ko05166 HTLV-I infection","KOG3913-Wnt family of developmental regulators[T]"]
["HMOX1",65.048889,26.554073,-1.292591251,{"v":7.45e-72,"d":"7.45E-72"},{"v":4.08e-71,"d":"4.08E-71"},"down","HMOX1","heme oxygenase 1","GO:0002246;GO:0004392;GO:0005634;GO:0005783;GO:0006788;GO:0006879;GO:0006979;GO:0016020;GO:0016021;GO:0016239;GO:0016242;GO:0016491;GO:0020037;GO:0034101;GO:0034395;GO:0034605;GO:0035094;GO:0042167;GO:0042168;GO:0042803;GO:0043065;GO:0043231;GO:0045766;GO:0046872;GO:0048471;GO:0048661;GO:0048662;GO:0051260;GO:0055072;GO:0055114;GO:0071243;GO:0071276;GO:0071456;GO:0072719;GO:0090050;GO:1902042;GO:1903589","K00510-ko00860 Porphyrin and chlorophyll metabolism;ko04978 Mineral absorption","KOG4480-Heme oxygenase[P]"]
["LOC107053523",5.529489,2.25308,-1.295247622,{"v":6.28e-11,"d":"6.28E-11"},{"v":1.42e-10,"d":"1.42E-10"},"down","LOC107053523","-","-","-","-"]
["PEBP1",641.933167,261.011017,-1.2983124,0,0,"down","PEBP1","phosphatidylethanolamine binding protein 1","GO:0019899;GO:0019901","-","-"]
["SYT11",41.312523,16.793175,-1.298704151,{"v":1.05e-213,"d":"1.05E-213"},{"v":1.21e-212,"d":"1.21E-212"},"down","SYT11","-","GO:0000149;GO:0001778;GO:0001891;GO:0005509;GO:0005544;GO:0005737;GO:0005764;GO:0005886;GO:0005887;GO:0006906;GO:0009611;GO:0016020;GO:0016021;GO:0017158;GO:0019905;GO:0030276;GO:0031369;GO:0031625;GO:0032009;GO:0042803;GO:0043005;GO:0045202;GO:0045335;GO:0048487;GO:0048791;GO:0050765;GO:0051289;GO:0055037;GO:0098793;GO:1900165;GO:1900424;GO:1904468;GO:1905171;GO:1990927","-","KOG1028-Ca2+-dependent phospholipid-binding protein Synaptotagmin, required for synaptic vesicle and secretory granule exocytosis[TU]"]
["PATJ",15.270935,6.202409,-1.299887829,{"v":1.54e-157,"d":"1.54E-157"},{"v":1.42e-156,"d":"1.42E-156"},"down","PATJ","-","-","K06092-ko04390 Hippo signaling pathway;ko04530 Tight junction","KOG3209-WW domain-containing protein[R]"]
["GTPBP1",74.789154,30.364922,-1.300423401,0,0,"down","GTPBP1","GTP binding protein 1","GO:0003924;GO:0005525","-","KOG0463-GTP-binding protein GP-1[R]"]
["ARHGEF10L",38.721867,15.713398,-1.30115332,{"v":4.58e-219,"d":"4.58E-219"},{"v":5.43e-218,"d":"5.43E-218"},"down","ARHGEF10L","-","GO:0005089;GO:0005096;GO:0005829;GO:0032933;GO:0035023;GO:0043547;GO:0051496","-","KOG3522-Predicted guanine nucleotide exchange factor[T]"]
["PRR15",13.029455,5.278544,-1.303564794,{"v":1.62e-52,"d":"1.62E-52"},{"v":7.49e-52,"d":"7.49E-52"},"down","PRR15","-","-","-","-"]
["TMEM135",16.084337,6.514787,-1.303866553,{"v":1.06e-68,"d":"1.06E-68"},{"v":5.67e-68,"d":"5.67E-68"},"down","TMEM135","-","-","-","KOG1398-Uncharacterized conserved protein[S]"]
["DPT",65.97908,26.712296,-1.304504676,0,0,"down","DPT","-","GO:0008285;GO:0030199","-","-"]
["TMEM150A",6.685016,2.704669,-1.305478967,{"v":2.12e-48,"d":"2.12E-48"},{"v":9.39e-48,"d":"9.39E-48"},"down","TMEM150A","-","GO:0005764;GO:0005887;GO:0016020;GO:0016021;GO:0046854;GO:0072659","-","-"]
["VASP",26.62549,10.770416,-1.305734102,{"v":3.47e-50,"d":"3.47E-50"},{"v":1.57e-49,"d":"1.57E-49"},"down","VASP","-","-","K06274-ko04015 Rap1 signaling pathway;ko04022 cGMP - PKG signaling pathway;ko04510 Focal adhesion;ko04611 Platelet activation;ko04666 Fc gamma R-mediated phagocytosis;ko04670 Leukocyte transendothelial migration","-"]
["ATP1B3",260.097534,105.169357,-1.306338311,0,0,"down","ATP1B3","ATPase Na /K  transporting subunit beta 3","GO:0001671;GO:0005391;GO:0005737;GO:0005886;GO:0005890;GO:0006811;GO:0006813;GO:0006814;GO:0006883;GO:0010248;GO:0016020;GO:0016021;GO:0030007;GO:0032781;GO:0036376;GO:0050821;GO:0051117;GO:0072659;GO:0086009;GO:1901018;GO:1903278;GO:1903288","K01540-ko04024 cAMP signaling pathway;ko04022 cGMP - PKG signaling pathway;ko04911 Insulin secretion;ko04918 Thyroid hormone synthesis;ko04919 Thyroid hormone signaling pathway;ko04260 Cardiac muscle contraction;ko04261 Adrenergic signaling in cardiomyocytes;ko04970 Salivary secretion;ko04971 Gastric acid secretion;ko04972 Pancreatic secretion;ko04976 Bile secretion;ko04973 Carbohydrate digestion and absorption;ko04974 Protein digestion and absorption;ko04978 Mineral absorption;ko04960 Aldosterone-regulated sodium reabsorption;ko04961 Endocrine and other factor-regulated calcium reabsorption;ko04964 Proximal tubule bicarbonate reclamation","KOG3927-Na+/K+ ATPase, beta subunit[P]"]
["GFRA4",13.701214,5.539076,-1.306586491,{"v":5.15e-89,"d":"5.15E-89"},{"v":3.21e-88,"d":"3.21E-88"},"down","GFRA4","GDNF family receptor alpha 4","GO:0005886;GO:0016020;GO:0031225;GO:0038023","-","-"]
["TOMM34",23.099262,9.31783,-1.309780845,{"v":7.84e-55,"d":"7.84E-55"},{"v":3.7e-54,"d":"3.70E-54"},"down","TOMM34","-","-","-","-"]
["SEMA3G",41.890728,16.894087,-1.310112571,{"v":1.76e-133,"d":"1.76E-133"},{"v":1.45e-132,"d":"1.45E-132"},"down","SEMA3G","-","GO:0005102;GO:0005615;GO:0030517;GO:0038191;GO:0050919","-","KOG3611-Semaphorins[T]"]
["MPZL3",83.547592,33.663521,-1.311412166,{"v":3.81e-192,"d":"3.81E-192"},{"v":4.05e-191,"d":"4.05E-191"},"down","MPZL3","myelin protein zero like 3","GO:0016020;GO:0016021;GO:0030198","-","-"]
["SRSF4",20.206774,8.13089,-1.313353832,{"v":7.57e-55,"d":"7.57E-55"},{"v":3.58e-54,"d":"3.58E-54"},"down","SRSF4","-","-","K12893-ko03040 Spliceosome;ko05168 Herpes simplex infection","KOG0106-Alternative splicing factor SRp55/B52/SRp75 (RRM superfamily)[A]"]
["IGFBP7",654.619995,263.06665,-1.315229305,0,0,"down","IGFBP7","-","GO:0001558;GO:0005520;GO:0005576","-","KOG4194-Membrane glycoprotein LIG-1[T]"]
["PPP3CB",57.134491,22.953613,-1.315640678,{"v":1.2e-86,"d":"1.20E-86"},{"v":7.33e-86,"d":"7.33E-86"},"down","PPP3CB","protein phosphatase 3 catalytic subunit beta","GO:0001915;GO:0001946;GO:0004721;GO:0004722;GO:0005509;GO:0005516;GO:0005737;GO:0005886;GO:0005955;GO:0006468;GO:0006470;GO:0007507;GO:0008144;GO:0010468;GO:0016787;GO:0017156;GO:0019899;GO:0030018;GO:0030217;GO:0030315;GO:0030346;GO:0031987;GO:0033173;GO:0033192;GO:0034097;GO:0035176;GO:0035690;GO:0035774;GO:0043029;GO:0045944;GO:0046983;GO:0098978;GO:1900242;GO:0004721;GO:0006470;GO:0016787;GO:0019855;GO:0030424;GO:0043204","K04348-ko04010 MAPK signaling pathway;ko04310 Wnt signaling pathway;ko04370 VEGF signaling pathway;ko04020 Calcium signaling pathway;ko04022 cGMP - PKG signaling pathway;ko04114 Oocyte meiosis;ko04650 Natural killer cell mediated cytotoxicity;ko04660 T cell receptor signaling pathway;ko04662 B cell receptor signaling pathway;ko04922 Glucagon signaling pathway;ko04921 Oxytocin signaling pathway;ko04924 Renin secretion;ko04724 Glutamatergic synapse;ko04728 Dopaminergic synapse;ko04720 Long-term potentiation;ko04360 Axon guidance;ko04380 Osteoclast differentiation;ko05010 Alzheimer's disease;ko05014 Amyotrophic lateral sclerosis (ALS);ko05031 Amphetamine addiction;ko05152 Tuberculosis;ko05166 HTLV-I infection","KOG0375-Serine-threonine phosphatase 2B, catalytic subunit[R]"]
["PRKCE",13.366079,5.365193,-1.316874332,{"v":4.69e-55,"d":"4.69E-55"},{"v":2.22e-54,"d":"2.22E-54"},"down","PRKCE","-","GO:0000166;GO:0002281;GO:0003785;GO:0004672;GO:0004674;GO:0004697;GO:0004699;GO:0005524;GO:0005622;GO:0005634;GO:0005737;GO:0005739;GO:0005783;GO:0005794;GO:0005829;GO:0005886;GO:0006468;GO:0008047;GO:0010634;GO:0010763;GO:0010811;GO:0016020;GO:0016021;GO:0016301;GO:0016310;GO:0016740;GO:0018105;GO:0019216;GO:0019899;GO:0030546;GO:0030838;GO:0031397;GO:0031663;GO:0032024;GO:0032230;GO:0032467;GO:0035276;GO:0035556;GO:0035641;GO:0035669;GO:0043085;GO:0043123;GO:0043278;GO:0043410;GO:0046872;GO:0048471;GO:0050730;GO:0050996;GO:0051209;GO:0051279;GO:0061178;GO:0070257;GO:0071361;GO:0071380;GO:0071456;GO:0071889;GO:0071944;GO:0090303;GO:2000273;GO:2001031","K18050-ko04071 Sphingolipid signaling pathway;ko04022 cGMP - PKG signaling pathway;ko04530 Tight junction;ko04666 Fc gamma R-mediated phagocytosis;ko04925 Aldosterone synthesis and secretion;ko04270 Vascular smooth muscle contraction;ko04750 Inflammatory mediator regulation of TRP channels;ko05206 MicroRNAs in cancer;ko04930 Type II diabetes mellitus;ko04931 Insulin resistance;ko04933 AGE-RAGE signaling pathway in diabetic complications","KOG0696-Serine/threonine protein kinase[T]"]
["INSIG1",32.979713,13.202442,-1.320774041,{"v":6.51e-141,"d":"6.51E-141"},{"v":5.53e-140,"d":"5.53E-140"},"down","INSIG1","insulin induced gene 1","GO:0005783;GO:0005789;GO:0006629;GO:0006641;GO:0006695;GO:0006991;GO:0008202;GO:0008203;GO:0010894;GO:0016020;GO:0016021;GO:0016126;GO:0032933;GO:0032937;GO:0036315;GO:0036316;GO:0042472;GO:0042474;GO:0042632;GO:0045599;GO:0045717;GO:0060021;GO:0060363;GO:0070862;GO:1901303;GO:0005783;GO:0005789;GO:0006629;GO:0006641;GO:0006695;GO:0006991;GO:0008202;GO:0008203;GO:0010894;GO:0016020;GO:0016021;GO:0016126;GO:0032933;GO:0032937;GO:0036315;GO:0036316;GO:0042472;GO:0042474;GO:0042632;GO:0045599;GO:0045717;GO:0060021;GO:0060363;GO:0070862;GO:1901303","-","KOG4363-Putative growth response protein[T]"]
["FAM72A",5.284544,2.114295,-1.321602303,{"v":5.35e-15,"d":"5.35E-15"},{"v":1.38e-14,"d":"1.38E-14"},"down","FAM72A","-","-","-","-"]
["HIGD1A",149.853912,59.940922,-1.321943566,{"v":1.44e-262,"d":"1.44E-262"},{"v":1.96e-261,"d":"1.96E-261"},"down","HIGD1A","HIG1 hypoxia inducible domain family member 1A","GO:0005634;GO:0005739;GO:0005743;GO:0016020;GO:0016021;GO:0042149;GO:0071456;GO:0071902;GO:0090201","-","KOG4431-Uncharacterized protein, induced by hypoxia [R]"]
["FOXA1",47.94635,19.167749,-1.32274007,{"v":8.32e-163,"d":"8.32E-163"},{"v":7.85e-162,"d":"7.85E-162"},"down","FOXA1","-","GO:0000122;GO:0001228;GO:0001650;GO:0003677;GO:0003700;GO:0005634;GO:0005654;GO:0005902;GO:0006338;GO:0006355;GO:0006357;GO:0006366;GO:0007219;GO:0008134;GO:0010468;GO:0010719;GO:0019904;GO:0021904;GO:0030324;GO:0032355;GO:0033148;GO:0035239;GO:0042445;GO:0042593;GO:0043065;GO:0043565;GO:0044212;GO:0045666;GO:0045880;GO:0045931;GO:0045944;GO:0048646;GO:0048665;GO:0051091;GO:0051726;GO:0060425;GO:0060441;GO:0060487;GO:0060528;GO:0060738;GO:0060740;GO:0060741;GO:0060743;GO:0061144;GO:0061448;GO:1902691","-","KOG3563-Forkhead/HNF-3-related transcription factor[K]"]
["GPAT3",56.458996,22.565224,-1.323102374,{"v":1.58e-169,"d":"1.58E-169"},{"v":1.54e-168,"d":"1.54E-168"},"down","GPAT3","glycerol-3-phosphate acyltransferase 3","GO:0003841;GO:0004366;GO:0005783;GO:0005789;GO:0006629;GO:0008152;GO:0008654;GO:0016020;GO:0016021;GO:0016024;GO:0016740;GO:0016746;GO:0019432;GO:0102420","K13506-ko00561 Glycerolipid metabolism;ko00564 Glycerophospholipid metabolism","KOG2898-Predicted phosphate acyltransferase, contains PlsC domain[I]"]
["PMEPA1",6.656071,2.65914,-1.323711088,{"v":1.24e-09,"d":"1.24E-09"},{"v":2.68e-09,"d":"2.68E-09"},"down","PMEPA1","prostate transmembrane protein, androgen induced 1","GO:0010991;GO:0016020;GO:0016021;GO:0030512;GO:0070412;GO:0000139;GO:0010008;GO:0010991;GO:0016020;GO:0016021;GO:0030512;GO:0031901;GO:0043231;GO:0050699;GO:0060394;GO:0070412","-","-"]
["MVD",36.5881,14.611267,-1.324293214,{"v":6.55e-69,"d":"6.55E-69"},{"v":3.51e-68,"d":"3.51E-68"},"down","MVD","-","GO:0000166;GO:0004163;GO:0005524;GO:0005829;GO:0006629;GO:0006694;GO:0006695;GO:0008202;GO:0008203;GO:0008284;GO:0008299;GO:0016126;GO:0016829;GO:0016831;GO:0019287;GO:0030544;GO:0042803","K01597-ko00900 Terpenoid backbone biosynthesis","KOG2833-Mevalonate pyrophosphate decarboxylase[I]"]
["WFS1",49.907551,19.917788,-1.325200676,{"v":8.94e-243,"d":"8.94E-243"},{"v":1.15e-241,"d":"1.15E-241"},"down","WFS1","-","GO:0000122;GO:0001822;GO:0003091;GO:0005783;GO:0007601;GO:0007605;GO:0016020;GO:0016021;GO:0030176;GO:0030433;GO:0030968;GO:0031398;GO:0031625;GO:0032469;GO:0034976;GO:0042593;GO:0043069;GO:0043433;GO:0043524;GO:0045927;GO:0050821;GO:0050877;GO:0051117;GO:0051247;GO:0051928;GO:0055074;GO:1902236;GO:1903892;GO:2000675","K14020-ko04141 Protein processing in endoplasmic reticulum","-"]
["TMEM254",108.049553,43.097343,-1.32602227,{"v":2.87e-268,"d":"2.87E-268"},{"v":3.98e-267,"d":"3.98E-267"},"down","TMEM254","transmembrane protein 254","GO:0016020;GO:0016021","-","-"]
["FURIN",94.705109,37.757908,-1.326663422,0,0,"down","FURIN","furin, paired basic amino acid cleaving enzyme","GO:0000139;GO:0002020;GO:0004175;GO:0004252;GO:0004867;GO:0005783;GO:0005802;GO:0006465;GO:0006508;GO:0008233;GO:0008236;GO:0008283;GO:0009966;GO:0009986;GO:0010951;GO:0016020;GO:0016021;GO:0016485;GO:0016486;GO:0016787;GO:0019058;GO:0030140;GO:0031638;GO:0032804;GO:0032902;GO:0032911;GO:0032940;GO:0042176;GO:0042277;GO:0043043;GO:0045121;GO:0045714;GO:0048406;GO:0052548;GO:0090472","K01349-ko05164 Influenza A","KOG3526-Subtilisin-like proprotein convertase[O]"]
["ITPK1",28.243504,11.257092,-1.327084896,{"v":2.1e-247,"d":"2.10E-247"},{"v":2.73e-246,"d":"2.73E-246"},"down","ITPK1","inositol-tetrakisphosphate 1-kinase","GO:0000166;GO:0000287;GO:0005524;GO:0005622;GO:0016301;GO:0016310;GO:0016324;GO:0016740;GO:0021915;GO:0032957;GO:0046872;GO:0047325;GO:0052725;GO:0052726;GO:0000166;GO:0000287;GO:0000825;GO:0005524;GO:0005622;GO:0016301;GO:0016310;GO:0016740;GO:0016853;GO:0032957;GO:0046872;GO:0047325;GO:0052725;GO:0052726;GO:0070266","K00913-ko00562 Inositol phosphate metabolism;ko04070 Phosphatidylinositol signaling system","-"]
["GPRC5C",17.677645,7.043863,-1.327487338,{"v":1.26e-50,"d":"1.26E-50"},{"v":5.72e-50,"d":"5.72E-50"},"down","GPRC5C","-","GO:0004930;GO:0007186;GO:0016020;GO:0016021","-","KOG1056-Glutamate-gated metabotropic ion channel receptor subunit GRM2 and related subunits, G-protein coupled receptor superfamily[PT]"]
["FAM102A",11.819891,4.703932,-1.329277622,{"v":3.15e-139,"d":"3.15E-139"},{"v":2.65e-138,"d":"2.65E-138"},"down","FAM102A","family with sequence similarity 102 member A","-","-","-"]
["FXYD6",134.051697,53.307003,-1.330392504,0,0,"down","FXYD6","FXYD domain containing ion transport regulator 6","GO:0005216;GO:0005887;GO:0006811;GO:0016020;GO:0016021;GO:0017080;GO:0034220;GO:0098978;GO:0099055;GO:0099056;GO:2000649","-","-"]
["RNLS",13.671227,5.431539,-1.33170979,{"v":2.7e-26,"d":"2.70E-26"},{"v":8.85e-26,"d":"8.85E-26"},"down","RNLS","renalase, FAD-dependent amine oxidase","GO:0005576;GO:0010459;GO:0016491;GO:0016651;GO:0045776;GO:0051379;GO:0055114;GO:0070404;GO:0097621","-","-"]
["EXPH5",24.239124,9.628342,-1.331978268,{"v":9.57e-237,"d":"9.57E-237"},{"v":1.2e-235,"d":"1.20E-235"},"down","EXPH5","-","-","-","-"]
["MMP28",37.959694,15.060859,-1.333664306,{"v":1.48e-130,"d":"1.48E-130"},{"v":1.19e-129,"d":"1.19E-129"},"down","MMP28","-","GO:0004222;GO:0005737;GO:0006508;GO:0008233;GO:0008237;GO:0008270;GO:0010760;GO:0016787;GO:0031012;GO:0046872","-","KOG1565-Gelatinase A and related matrix metalloproteases[OW]"]
["SC5D",71.92247,28.497311,-1.335616774,{"v":1.44e-182,"d":"1.44E-182"},{"v":1.47e-181,"d":"1.47E-181"},"down","SC5D","-","GO:0005506;GO:0008610;GO:0016020;GO:0016021;GO:0016491;GO:0055114","K00227-ko00100 Steroid biosynthesis","KOG0872-Sterol C5 desaturase[I]"]
["IFI27L2",621.295776,246.115585,-1.335944228,0,0,"down","IFI27L2","interferon, alpha-inducible protein 27-like 2","GO:0016020;GO:0016021","-","-"]
["CCNG2",92.790039,36.756359,-1.335976077,0,0,"down","CCNG2","-","GO:0051726","K10146-ko04068 FoxO signaling pathway;ko04115 p53 signaling pathway","-"]
["DIO1",5.503324,2.178187,-1.337175451,{"v":5.46e-11,"d":"5.46E-11"},{"v":1.24e-10,"d":"1.24E-10"},"down","DIO1","iodothyronine deiodinase 1","GO:0004800;GO:0005783;GO:0005789;GO:0016020;GO:0016021;GO:0016491;GO:0042446;GO:0055114","-","-"]
["SFRP1",15.845339,6.266887,-1.338237641,{"v":5.76e-79,"d":"5.76E-79"},{"v":3.33e-78,"d":"3.33E-78"},"down","SFRP1","secreted frizzled related protein 1","GO:0001649;GO:0001657;GO:0001756;GO:0001843;GO:0002244;GO:0004197;GO:0004930;GO:0005109;GO:0005576;GO:0005615;GO:0005622;GO:0005829;GO:0006508;GO:0007186;GO:0007275;GO:0008144;GO:0008201;GO:0008284;GO:0008285;GO:0008584;GO:0008585;GO:0009267;GO:0009950;GO:0009952;GO:0009986;GO:0010564;GO:0010629;GO:0010719;GO:0010975;GO:0014034;GO:0014070;GO:0016021;GO:0016055;GO:0017147;GO:0021915;GO:0030097;GO:0030154;GO:0030177;GO:0030178;GO:0030279;GO:0030307;GO:0030308;GO:0030336;GO:0030514;GO:0033689;GO:0035019;GO:0035567;GO:0042493;GO:0042802;GO:0042813;GO:0043065;GO:0043066;GO:0043508;GO:0044344;GO:0044345;GO:0045578;GO:0045600;GO:0045668;GO:0045671;GO:0045880;GO:0045892;GO:0045893;GO:0046546;GO:0046676;GO:0046851;GO:0048147;GO:0048546;GO:0050679;GO:0050680;GO:0050732;GO:0060070;GO:0060071;GO:0060218;GO:0060346;GO:0060527;GO:0060687;GO:0060766;GO:0062023;GO:0071305;GO:0071347;GO:0071356;GO:0071363;GO:0071380;GO:0071391;GO:0071392;GO:0071456;GO:0071481;GO:0071504;GO:0071542;GO:0071560;GO:0071773;GO:0090090;GO:0090175;GO:0090179;GO:0090244;GO:0090246;GO:0090263;GO:1902043;GO:1904956;GO:2000041;GO:2000052;GO:2000054;GO:2000080;GO:2000270;GO:2000271;GO:2001238","K02166-ko04310 Wnt signaling pathway","KOG3577-Smoothened and related G-protein-coupled receptors[T]"]
["TTC39C",5.715721,2.260466,-1.338315278,{"v":5.5e-39,"d":"5.50E-39"},{"v":2.18e-38,"d":"2.18E-38"},"down","TTC39C","-","-","-","KOG3783-Uncharacterized conserved protein[S]"]
["TPRN",27.202654,10.754539,-1.338801729,{"v":1.83e-143,"d":"1.83E-143"},{"v":1.58e-142,"d":"1.58E-142"},"down","TPRN","-","GO:0007605;GO:0019902","-","-"]
["CLIC3",128.549973,50.801907,-1.339374748,{"v":6.17e-249,"d":"6.17E-249"},{"v":8.08e-248,"d":"8.08E-248"},"down","CLIC3","-","GO:0005254;GO:0005634;GO:0005737;GO:0006821;GO:0016604;GO:1902476","-","KOG1422-Intracellular Cl- channel CLIC, contains GST domain[P]"]
["EPHA3",18.916622,7.471618,-1.340161883,{"v":5.26e-160,"d":"5.26E-160"},{"v":4.91e-159,"d":"4.91E-159"},"down","EPHA3","EPH receptor A3","GO:0000166;GO:0004672;GO:0004713;GO:0004714;GO:0005003;GO:0005004;GO:0005524;GO:0005769;GO:0005886;GO:0005887;GO:0006468;GO:0007169;GO:0010717;GO:0016020;GO:0016021;GO:0016301;GO:0016310;GO:0016477;GO:0016740;GO:0018108;GO:0032956;GO:0043087;GO:0048013;GO:0051893;GO:0070507;GO:0097155;GO:0097156;GO:0000166;GO:0004672;GO:0004713;GO:0005003;GO:0005004;GO:0005524;GO:0005769;GO:0005887;GO:0006468;GO:0007169;GO:0010976;GO:0016020;GO:0016021;GO:0016301;GO:0016310;GO:0016740;GO:0018108;GO:0032956;GO:0043087;GO:0045806;GO:0048013;GO:0051893;GO:0070507;GO:0071300;GO:1903078","-","KOG0196-Tyrosine kinase, EPH (ephrin) receptor family[T]"]
["RGS2",69.791985,27.560604,-1.340453859,{"v":3.58e-131,"d":"3.58E-131"},{"v":2.9e-130,"d":"2.90E-130"},"down","RGS2","regulator of G-protein signaling 2","GO:0001965;GO:0005096;GO:0005634;GO:0005737;GO:0005829;GO:0005886;GO:0007283;GO:0008277;GO:0009898;GO:0010519;GO:0010614;GO:0043407;GO:0043547;GO:0043951;GO:0045744;GO:0055119;GO:0060087;GO:0060452;GO:0140194","-","KOG3589-G protein signaling regulators[T]"]
["BLVRA",14.706396,5.805305,-1.340999967,{"v":1.88e-70,"d":"1.88E-70"},{"v":1.02e-69,"d":"1.02E-69"},"down","BLVRA","-","GO:0004074;GO:0005737;GO:0005829;GO:0008270;GO:0016491;GO:0042167;GO:0046872;GO:0055114","K00214-ko00860 Porphyrin and chlorophyll metabolism","-"]
["ABL1",63.606419,25.106236,-1.341126614,0,0,"down","ABL1","-","GO:0000166;GO:0000287;GO:0001784;GO:0001843;GO:0001922;GO:0001934;GO:0002322;GO:0002333;GO:0004672;GO:0004713;GO:0004715;GO:0005080;GO:0005102;GO:0005524;GO:0005634;GO:0005654;GO:0005730;GO:0005737;GO:0005829;GO:0006468;GO:0006909;GO:0006974;GO:0006975;GO:0006979;GO:0007169;GO:0007173;GO:0007204;GO:0007229;GO:0008022;GO:0009791;GO:0010595;GO:0015629;GO:0016301;GO:0016310;GO:0016604;GO:0016740;GO:0017124;GO:0018108;GO:0019904;GO:0019905;GO:0021587;GO:0022408;GO:0030035;GO:0030036;GO:0030145;GO:0030154;GO:0030182;GO:0030514;GO:0030516;GO:0031113;GO:0031234;GO:0031252;GO:0032489;GO:0032956;GO:0032991;GO:0033690;GO:0034446;GO:0035791;GO:0038083;GO:0038189;GO:0038191;GO:0042100;GO:0042127;GO:0042169;GO:0042770;GO:0043065;GO:0043123;GO:0043124;GO:0043542;GO:0045087;GO:0045184;GO:0045580;GO:0045930;GO:0045931;GO:0046632;GO:0046777;GO:0046875;GO:0048008;GO:0048471;GO:0048536;GO:0048538;GO:0048668;GO:0050731;GO:0050798;GO:0050853;GO:0050885;GO:0051015;GO:0051019;GO:0051281;GO:0051353;GO:0051444;GO:0051496;GO:0051726;GO:0051894;GO:0060020;GO:0060563;GO:0070064;GO:0070301;GO:0070373;GO:0070374;GO:0071222;GO:0071901;GO:0072358;GO:0090050;GO:0090135;GO:1900026;GO:1900042;GO:1900272;GO:1900275;GO:1901216;GO:1902715;GO:1903053;GO:1904528;GO:1904531;GO:1905244;GO:1905555;GO:1990051;GO:2000096;GO:2000251;GO:2000352;GO:2000772;GO:2000773;GO:2001020","K06619-ko04014 Ras signaling pathway;ko04012 ErbB signaling pathway;ko04110 Cell cycle;ko04722 Neurotrophin signaling pathway;ko04360 Axon guidance;ko05200 Pathways in cancer;ko05206 MicroRNAs in cancer;ko05220 Chronic myeloid leukemia;ko05416 Viral myocarditis;ko05130 Pathogenic Escherichia coli infection;ko05131 Shigellosis","KOG4278-Protein tyrosine kinase[T]"]
["BRAP",39.292831,15.50347,-1.341674959,{"v":3.35e-186,"d":"3.35E-186"},{"v":3.47e-185,"d":"3.47E-185"},"down","BRAP","BRCA1 associated protein","GO:0000151;GO:0000165;GO:0003676;GO:0004842;GO:0005737;GO:0005829;GO:0007265;GO:0008139;GO:0008270;GO:0009968;GO:0016567;GO:0031965;GO:0042802;GO:0061630","-","KOG0804-Cytoplasmic Zn-finger protein BRAP2 (BRCA1 associated protein)[R]"]
["SEMA5A",35.824467,14.128296,-1.342357766,{"v":7.1e-235,"d":"7.10E-235"},{"v":8.87e-234,"d":"8.87E-234"},"down","SEMA5A","-","GO:0016020;GO:0016021","-","KOG3611-Semaphorins[T]"]
["GXYLT2",56.683548,22.336418,-1.343532219,{"v":4.34e-213,"d":"4.34E-213"},{"v":5.02e-212,"d":"5.02E-212"},"down","GXYLT2","-","GO:0016266;GO:0016740;GO:0016757;GO:0035252","K13676-ko00514 Other types of O-glycan biosynthesis","KOG3765-Predicted glycosyltransferase[G]"]
["PLD1",43.474606,17.126385,-1.34395229,0,0,"down","PLD1","-","GO:0003824;GO:0004630;GO:0005794;GO:0006654;GO:0016042;GO:0016787;GO:0032534;GO:0035091;GO:0048017;GO:0048870;GO:0070290","K01115-ko00564 Glycerophospholipid metabolism;ko00565 Ether lipid metabolism;ko04014 Ras signaling pathway;ko04072 Phospholipase D signaling pathway;ko04071 Sphingolipid signaling pathway;ko04024 cAMP signaling pathway;ko04144 Endocytosis;ko04666 Fc gamma R-mediated phagocytosis;ko04912 GnRH signaling pathway;ko04724 Glutamatergic synapse;ko05231 Choline metabolism in cancer","KOG1329-Phospholipase D1[I]"]
["UBE2R2",77.368149,30.476683,-1.344033866,{"v":1.69e-200,"d":"1.69E-200"},{"v":1.86e-199,"d":"1.86E-199"},"down","UBE2R2","ubiquitin conjugating enzyme E2 R2","GO:0000166;GO:0005524;GO:0016740;GO:0000166;GO:0005524;GO:0005737;GO:0016567;GO:0016740;GO:0031625;GO:0043161;GO:0061630","K02207-ko04120 Ubiquitin mediated proteolysis;ko05168 Herpes simplex infection","KOG0425-Ubiquitin-protein ligase[O]"]
["MAPKAPK5",39.27092,15.454464,-1.345437778,{"v":1.26e-228,"d":"1.26E-228"},{"v":1.54e-227,"d":"1.54E-227"},"down","MAPKAPK5","mitogen-activated protein kinase-activated protein kinase 5","GO:0000165;GO:0002039;GO:0004672;GO:0004674;GO:0004683;GO:0005516;GO:0005524;GO:0005634;GO:0005654;GO:0005737;GO:0005829;GO:0006417;GO:0006468;GO:0007166;GO:0007265;GO:0009931;GO:0018105;GO:0032007;GO:0032212;GO:0046777;GO:0051019;GO:0051973;GO:0090400;GO:1904355","K04442-ko04010 MAPK signaling pathway","KOG0604-MAP kinase-activated protein kinase 2[T]"]
["GNE",126.269379,49.671455,-1.346015908,0,0,"down","GNE","glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase","GO:0004553;GO:0006047","K12409-ko00520 Amino sugar and nucleotide sugar metabolism","-"]
["RAD54L",8.443215,3.317641,-1.34763467,{"v":2.56e-33,"d":"2.56E-33"},{"v":9.41e-33,"d":"9.41E-33"},"down","RAD54L","RAD54-like (S. cerevisiae)","GO:0000724;GO:0000733;GO:0005524;GO:0005654;GO:0006302;GO:0006974;GO:0008340;GO:0010212;GO:0032991;GO:0036310;GO:0042493;GO:0051276;GO:0000166;GO:0000733;GO:0003677;GO:0004386;GO:0005524;GO:0005634;GO:0006281;GO:0006974;GO:0016787;GO:0036310","K10875-ko03440 Homologous recombination","KOG0390-DNA repair protein, SNF2 family[L]"]
["TRIM47",52.301685,20.501112,-1.351155261,0,0,"down","TRIM47","-","GO:0004842;GO:0005829;GO:0016567","-","-"]
["AQP3",763.935852,299.333954,-1.351695564,0,0,"down","AQP3","-","GO:0002684;GO:0005634;GO:0005737;GO:0005886;GO:0005911;GO:0006833;GO:0015254;GO:0015267;GO:0015793;GO:0015840;GO:0016020;GO:0016021;GO:0016323;GO:0032526;GO:0055085;GO:0070295;GO:0071456;GO:0090650","-","KOG0224-Aquaporin (major intrinsic protein family)[G]"]
["NBEAL2",29.704424,11.633405,-1.35240439,0,0,"down","NBEAL2","-","GO:0005783;GO:0030220","-","KOG1787-Kinase A-anchor protein Neurobeachin and related BEACH and WD40 repeat proteins[U]"]
["AUTS2",26.956799,10.556098,-1.352572544,{"v":1.62e-173,"d":"1.62E-173"},{"v":1.6e-172,"d":"1.60E-172"},"down","AUTS2","-","GO:0003682;GO:0045944;GO:0051571;GO:2000620","-","-"]
["EPS8L2",172.884842,67.699104,-1.352602739,0,0,"down","EPS8L2","-","GO:0003779;GO:0005089;GO:0005829;GO:0005886;GO:0007266;GO:0007605;GO:0030676;GO:0032421;GO:0032426;GO:0032587;GO:0032991;GO:0035023;GO:1900029","-","-"]
["CD38",6.262207,2.451715,-1.352879916,{"v":1.21e-09,"d":"1.21E-09"},{"v":2.6e-09,"d":"2.60E-09"},"down","CD38","CD38 molecule","GO:0003953;GO:0005886;GO:0008152;GO:0009986;GO:0016020;GO:0016787;GO:0016798;GO:0016849;GO:0030890;GO:0042493;GO:0042802;GO:0043066;GO:0045892;GO:0045893;GO:0050135;GO:0050853;GO:0061810","K01242-ko00760 Nicotinate and nicotinamide metabolism;ko04020 Calcium signaling pathway;ko04921 Oxytocin signaling pathway;ko04970 Salivary secretion;ko04972 Pancreatic secretion;ko05169 Epstein-Barr virus infection","-"]
["RGMA",56.46188,22.097408,-1.353400014,{"v":2.61e-110,"d":"2.61E-110"},{"v":1.87e-109,"d":"1.87E-109"},"down","RGMA","repulsive guidance molecule family member a","GO:0001843;GO:0005102;GO:0009986;GO:0010975;GO:0010977;GO:0015026;GO:0030509;GO:0030510;GO:0031175;GO:0043547;GO:0048681;GO:0051044;GO:1900121;GO:0005886;GO:0010975;GO:0015026;GO:0016020;GO:0030509;GO:0031225;GO:0048681","-","-"]
["RPS6KA5",35.833202,14.018575,-1.353957261,{"v":1.09e-194,"d":"1.09E-194"},{"v":1.17e-193,"d":"1.17E-193"},"down","RPS6KA5","ribosomal protein S6 kinase A5","GO:0000166;GO:0000287;GO:0004672;GO:0004674;GO:0005524;GO:0005622;GO:0006468;GO:0016301;GO:0016310;GO:0016740;GO:0035556;GO:0000166;GO:0000287;GO:0004672;GO:0004674;GO:0005524;GO:0005634;GO:0005654;GO:0005737;GO:0006355;GO:0006468;GO:0016301;GO:0016310;GO:0016572;GO:0016740;GO:0033129;GO:0035066;GO:0035556;GO:0043987;GO:0043988;GO:0043990;GO:0045892;GO:0045944;GO:0046872;GO:0051092;GO:0070498","K04445-ko04010 MAPK signaling pathway;ko04668 TNF signaling pathway;ko04261 Adrenergic signaling in cardiomyocytes;ko04722 Neurotrophin signaling pathway;ko04713 Circadian entrainment;ko05206 MicroRNAs in cancer;ko05219 Bladder cancer","KOG0603-Ribosomal protein S6 kinase[T]"]
["TUBA4B",58.04612,22.685696,-1.355416713,{"v":3.46e-115,"d":"3.46E-115"},{"v":2.56e-114,"d":"2.56E-114"},"down","TUBA4B","-","GO:0000166;GO:0003924;GO:0005200;GO:0005525;GO:0005737;GO:0005856;GO:0005874;GO:0007010;GO:0007017","-","-"]
["PIK3CD",7.773442,3.03609,-1.356338993,{"v":3.21e-82,"d":"3.21E-82"},{"v":1.9e-81,"d":"1.90E-81"},"down","PIK3CD","phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta","GO:0000166;GO:0002250;GO:0005524;GO:0005737;GO:0005886;GO:0005942;GO:0006468;GO:0006954;GO:0010628;GO:0014065;GO:0016301;GO:0016303;GO:0016310;GO:0016740;GO:0030168;GO:0030335;GO:0033031;GO:0035004;GO:0035005;GO:0036092;GO:0045087;GO:0046854;GO:0046934;GO:0048015;GO:0060326","K00922-ko00562 Inositol phosphate metabolism;ko04014 Ras signaling pathway;ko04015 Rap1 signaling pathway;ko04012 ErbB signaling pathway;ko04370 VEGF signaling pathway;ko04630 Jak-STAT signaling pathway;ko04668 TNF signaling pathway;ko04066 HIF-1 signaling pathway;ko04068 FoxO signaling pathway;ko04070 Phosphatidylinositol signaling system;ko04072 Phospholipase D signaling pathway;ko04071 Sphingolipid signaling pathway;ko04024 cAMP signaling pathway;ko04022 cGMP - PKG signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04152 AMPK signaling pathway;ko04150 mTOR signaling pathway;ko04810 Regulation of actin cytoskeleton;ko04210 Apoptosis;ko04510 Focal adhesion;ko04550 Signaling pathways regulating pluripotency of stem cells;ko04611 Platelet activation;ko04620 Toll-like receptor signaling pathway;ko04650 Natural killer cell mediated cytotoxicity;ko04660 T cell receptor signaling pathway;ko04662 B cell receptor signaling pathway;ko04664 Fc epsilon RI signaling pathway;ko04666 Fc gamma R-mediated phagocytosis;ko04670 Leukocyte transendothelial migration;ko04062 Chemokine signaling pathway;ko04910 Insulin signaling pathway;ko04923 Regulation of lipolysis in adipocyte;ko04915 Estrogen signaling pathway;ko04914 Progesterone-mediated oocyte maturation;ko04917 Prolactin signaling pathway;ko04921 Oxytocin signaling pathway;ko04919 Thyroid hormone signaling pathway;ko04261 Adrenergic signaling in cardiomyocytes;ko04973 Carbohydrate digestion and absorption;ko04960 Aldosterone-regulated sodium reabsorption;ko04725 Cholinergic synapse;ko04722 Neurotrophin signaling pathway;ko04750 Inflammatory mediator regulation of TRP channels;ko04360 Axon guidance;ko04380 Osteoclast differentiation;ko04211 Longevity regulating pathway - mammal;ko04212 Longevity regulating pathway - worm;ko04213 Longevity regulating pathway - multiple species;ko05200 Pathways in cancer;ko05230 Central carbon metabolism in cancer;ko05231 Choline metabolism in cancer;ko05205 Proteoglycans in cancer;ko05203 Viral carcinogenesis;ko05210 Colorectal cancer;ko05212 Pancreatic cancer;ko05214 Glioma;ko05221 Acute myeloid leukemia;ko05220 Chronic myeloid leukemia;ko05218 Melanoma;ko05211 Renal cell carcinoma;ko05215 Prostate cancer;ko05213 Endometrial cancer;ko05224 Breast cancer;ko05222 Small cell lung cancer;ko05223 Non-small cell lung cancer;ko04930 Type II diabetes mellitus;ko04932 Non-alcoholic fatty liver disease (NAFLD);ko04931 Insulin resistance;ko04933 AGE-RAGE signaling pathway in diabetic complications;ko05100 Bacterial invasion of epithelial cells;ko05166 HTLV-I infection;ko05162 Measles;ko05164 Influenza A;ko05161 Hepatitis B;ko05160 Hepatitis C;ko05169 Epstein-Barr virus infection;ko05146 Amoebiasis;ko05145 Toxoplasmosis;ko05142 Chagas disease (American trypanosomiasis);ko01521 EGFR tyrosine kinase inhibitor resistance;ko01522 Endocrine resistance;ko01524 Platinum drug resistance","KOG0904-Phosphatidylinositol 3-kinase catalytic subunit (p110)[T]"]
["MPP5",33.036598,12.897745,-1.356946279,{"v":7.71e-227,"d":"7.71E-227"},{"v":9.38e-226,"d":"9.38E-226"},"down","MPP5","membrane palmitoylated protein 5","GO:0002011;GO:0005737;GO:0005886;GO:0005913;GO:0007009;GO:0019904;GO:0032287;GO:0032991;GO:0035749;GO:0035750;GO:0043219;GO:0043220;GO:0070830;GO:0090162","K06091-ko04390 Hippo signaling pathway;ko04391 Hippo signaling pathway -fly;ko04530 Tight junction","KOG0609-Calcium/calmodulin-dependent serine protein kinase/membrane-associated guanylate kinase[T]"]
["SH3RF3",16.529388,6.449572,-1.35775798,{"v":2.1e-61,"d":"2.10E-61"},{"v":1.05e-60,"d":"1.05E-60"},"down","SH3RF3","-","GO:0046330;GO:0046872;GO:0051865;GO:0061630","-","KOG4225-Sorbin and SH3 domain-containing protein[T]"]
["VLDLR",119.790909,46.740952,-1.357759402,0,0,"down","VLDLR","very low density lipoprotein receptor","GO:0000122;GO:0005509;GO:0005615;GO:0006898;GO:0016020;GO:0016021;GO:0021517;GO:0030229;GO:0034185;GO:0034189;GO:0034436;GO:0034437;GO:0034447;GO:0038025;GO:0038026;GO:0043235;GO:0045860;GO:0048306;GO:0048813;GO:1900006;GO:0000122;GO:0005509;GO:0005615;GO:0005905;GO:0006629;GO:0006869;GO:0006897;GO:0006898;GO:0008202;GO:0008203;GO:0016020;GO:0016021;GO:0021517;GO:0030228;GO:0030229;GO:0034185;GO:0034189;GO:0034361;GO:0034436;GO:0034437;GO:0034447;GO:0038025;GO:0038026;GO:0043235;GO:0045860;GO:0048306;GO:0048813;GO:1900006","-","KOG1215-Low-density lipoprotein receptors containing Ca2+-binding EGF-like domains[T]"]
["PIK3R6",29.981422,11.691456,-1.358614203,{"v":1.13e-186,"d":"1.13E-186"},{"v":1.18e-185,"d":"1.18E-185"},"down","PIK3R6","-","GO:0005944;GO:0007186;GO:0016020;GO:0042269;GO:0043406;GO:0043551;GO:0045582;GO:0045766;GO:0046854;GO:0046934;GO:0046935","-","-"]
["SERPINF2",62.702461,24.421175,-1.360389452,{"v":9.57e-193,"d":"9.57E-193"},{"v":1.02e-191,"d":"1.02E-191"},"down","SERPINF2","-","GO:0002020;GO:0002034;GO:0004867;GO:0005577;GO:0005615;GO:0009986;GO:0010757;GO:0010951;GO:0030199;GO:0032967;GO:0042803;GO:0045597;GO:0045944;GO:0046330;GO:0048514;GO:0048661;GO:0051496;GO:0051918;GO:0070374;GO:0071636","-","KOG2392-Serpin[V]"]
["CNTN1",26.192173,10.198172,-1.360825181,{"v":4.98e-172,"d":"4.98E-172"},{"v":4.88e-171,"d":"4.88E-171"},"down","CNTN1","contactin 1","GO:0005515;GO:0005886;GO:0007155;GO:0007399;GO:0010628;GO:0010765;GO:0010976;GO:0016020;GO:0021549;GO:0030246;GO:0031175;GO:0031225;GO:0043209;GO:0099025;GO:0099026","K06759-ko04514 Cell adhesion molecules (CAMs)","KOG3513-Neural cell adhesion molecule L1[T]"]
["LOC112531696",9.522573,3.703619,-1.36241575,{"v":4.89e-13,"d":"4.89E-13"},{"v":1.19e-12,"d":"1.19E-12"},"down","LOC112531696","-","-","-","-"]
["TMEM200B",8.809564,3.426028,-1.362533677,{"v":8.64e-80,"d":"8.64E-80"},{"v":5.03e-79,"d":"5.03E-79"},"down","TMEM200B","-","GO:0016020;GO:0016021","-","KOG4823-Uncharacterized conserved protein[S]"]
["SEL1L3",101.264236,39.347935,-1.363764911,0,0,"down","SEL1L3","-","GO:0005634;GO:0005654;GO:0016020;GO:0016021","-","KOG1550-Extracellular protein SEL-1 and related proteins[MOT]"]
["GRIN3B",14.649217,5.684525,-1.365711847,{"v":1.65e-91,"d":"1.65E-91"},{"v":1.04e-90,"d":"1.04E-90"},"down","GRIN3B","-","GO:0004970;GO:0005216;GO:0005262;GO:0005886;GO:0006811;GO:0016020;GO:0016021;GO:0017146;GO:0034220;GO:0035235;GO:0038023;GO:0043025;GO:0051205;GO:0051924;GO:0070588","K05214-ko04024 cAMP signaling pathway;ko04080 Neuroactive ligand-receptor interaction;ko04724 Glutamatergic synapse;ko05030 Cocaine addiction;ko05031 Amphetamine addiction;ko05033 Nicotine addiction;ko05034 Alcoholism","KOG1053-Glutamate-gated NMDA-type ion channel receptor subunit GRIN2A and related subunits[PET]"]
["C1orf210",24.656887,9.528295,-1.371700682,{"v":2.83e-59,"d":"2.83E-59"},{"v":1.4e-58,"d":"1.40E-58"},"down","C1orf210","-","-","-","-"]
["TESC",6.073081,2.345838,-1.372325225,{"v":1.86e-08,"d":"1.86E-08"},{"v":3.82e-08,"d":"3.82E-08"},"down","TESC","tescalcin","GO:0000287;GO:0001726;GO:0004860;GO:0005509;GO:0005634;GO:0005737;GO:0005886;GO:0006469;GO:0016020;GO:0019212;GO:0030027;GO:0030154;GO:0030854;GO:0032417;GO:0032587;GO:0042803;GO:0042995;GO:0043086;GO:0046872;GO:0050821;GO:0051604;GO:0071300;GO:0072659;GO:0005509;GO:0005634;GO:0005737;GO:0005829;GO:0005886;GO:0008285;GO:0010628;GO:0030027;GO:0030854;GO:0032417;GO:0033628;GO:0045654;GO:0045893;GO:0050821;GO:0051604;GO:0071300;GO:0072659","-","KOG0034-Ca2+/calmodulin-dependent protein phosphatase (calcineurin subunit B), EF-Hand superfamily protein[T]"]
["DOPEY1",14.664605,5.659054,-1.373705403,{"v":1.24e-154,"d":"1.24E-154"},{"v":1.13e-153,"d":"1.13E-153"},"down","DOPEY1","-","GO:0005768;GO:0005802;GO:0005829;GO:0006895","-","-"]
["APCDD1L",58.002205,22.371885,-1.374420927,0,0,"down","APCDD1L","-","-","-","-"]
["RAB2B",52.403011,20.197098,-1.375501694,{"v":1.64e-190,"d":"1.64E-190"},{"v":1.73e-189,"d":"1.73E-189"},"down","RAB2B","-","-","-","-"]
["GLTP",60.471207,23.289497,-1.376568894,{"v":3.37e-94,"d":"3.37E-94"},{"v":2.17e-93,"d":"2.17E-93"},"down","GLTP","glycolipid transfer protein","GO:0005737;GO:0005829;GO:0008289;GO:0016020;GO:0042802;GO:0051861;GO:0120009;GO:0120013","-","KOG3221-Glycolipid transfer protein[G]"]
["ELF2",41.79071,16.093611,-1.376694203,{"v":4.19e-163,"d":"4.19E-163"},{"v":3.95e-162,"d":"3.95E-162"},"down","ELF2","-","GO:0000981;GO:0003677;GO:0003700;GO:0005634;GO:0005654;GO:0005829;GO:0006355;GO:0006357;GO:0016604;GO:0030154;GO:0043565;GO:0045893","-","KOG3804-Transcription factor NERF and related proteins, contain ETS domain[K]"]
["PKP2",24.550673,9.445137,-1.378118945,{"v":6.29e-124,"d":"6.29E-124"},{"v":4.89e-123,"d":"4.89E-123"},"down","PKP2","-","GO:0002159;GO:0005080;GO:0005654;GO:0005882;GO:0005886;GO:0005911;GO:0005912;GO:0007507;GO:0014704;GO:0019215;GO:0030054;GO:0030057;GO:0032947;GO:0045110;GO:0045294;GO:0048496;GO:0055010;GO:0072659;GO:0086002;GO:0086005;GO:0086019;GO:0086073;GO:0086091;GO:0098609;GO:0098911","-","KOG1048-Neural adherens junction protein Plakophilin and related Armadillo repeat proteins[TW]"]
["ANO10",35.035839,13.478917,-1.378126861,{"v":9.22e-103,"d":"9.22E-103"},{"v":6.27e-102,"d":"6.27E-102"},"down","ANO10","-","GO:0005227;GO:0005229;GO:0005622;GO:0005886;GO:0006812;GO:0006821;GO:0016020;GO:0016021;GO:0034220","-","KOG2513-Protein required for meiotic chromosome segregation[D]"]
["TNIK",34.441238,13.238635,-1.379382624,{"v":1.72e-257,"d":"1.72E-257"},{"v":2.32e-256,"d":"2.32E-256"},"down","TNIK","-","GO:0000185;GO:0001934;GO:0004672;GO:0004674;GO:0005524;GO:0005634;GO:0005654;GO:0005737;GO:0005829;GO:0005856;GO:0006468;GO:0007010;GO:0007256;GO:0007346;GO:0008349;GO:0016324;GO:0030033;GO:0031098;GO:0031532;GO:0035556;GO:0042981;GO:0046777;GO:0048812;GO:0048814;GO:0072659","-","KOG0587-Traf2- and Nck-interacting kinase and related germinal center kinase (GCK) family protein kinases[T]"]
["CHRM3",9.810094,3.764299,-1.381885734,{"v":1.81e-30,"d":"1.81E-30"},{"v":6.37e-30,"d":"6.37E-30"},"down","CHRM3","cholinergic receptor muscarinic 3","GO:0003056;GO:0004930;GO:0005886;GO:0005887;GO:0006939;GO:0007165;GO:0007186;GO:0007197;GO:0007207;GO:0007213;GO:0007271;GO:0016020;GO:0016021;GO:0016907;GO:0030054;GO:0045202;GO:0045211;GO:0045987;GO:0046541","K04131-ko04020 Calcium signaling pathway;ko04080 Neuroactive ligand-receptor interaction;ko04810 Regulation of actin cytoskeleton;ko04911 Insulin secretion;ko04970 Salivary secretion;ko04971 Gastric acid secretion;ko04972 Pancreatic secretion;ko04725 Cholinergic synapse;ko04742 Taste transduction","-"]
["GPX1",1665.090698,638.751282,-1.382274577,0,0,"down","GPX1","glutathione peroxidase 1","GO:0000302;GO:0001659;GO:0001885;GO:0002862;GO:0004602;GO:0005737;GO:0005739;GO:0005829;GO:0006629;GO:0006641;GO:0006749;GO:0006915;GO:0006979;GO:0007605;GO:0008283;GO:0008631;GO:0009410;GO:0009609;GO:0009611;GO:0009636;GO:0009650;GO:0010269;GO:0010332;GO:0014902;GO:0017124;GO:0018158;GO:0033194;GO:0033599;GO:0040029;GO:0042311;GO:0042542;GO:0042744;GO:0043066;GO:0043154;GO:0043403;GO:0043523;GO:0043534;GO:0045444;GO:0045454;GO:0048741;GO:0051450;GO:0051702;GO:0051897;GO:0055114;GO:0060047;GO:0060055;GO:0061136;GO:0090201;GO:0097413;GO:0098869;GO:1902042;GO:1902176","K00432-ko00590 Arachidonic acid metabolism;ko00480 Glutathione metabolism;ko04918 Thyroid hormone synthesis","KOG1651-Glutathione peroxidase[O]"]
["PFKFB4L",60.73835,23.292547,-1.382739313,0,0,"down","PFKFB4L","-","GO:0003824;GO:0003873;GO:0005524;GO:0006000;GO:0006003;GO:0008152;GO:0046835","K19030-ko00051 Fructose and mannose metabolism;ko04152 AMPK signaling pathway","-"]
["NF2L",8.884961,3.392751,-1.388909892,{"v":1.19e-46,"d":"1.19E-46"},{"v":5.18e-46,"d":"5.18E-46"},"down","NF2L","-","-","K16684-ko04390 Hippo signaling pathway;ko04391 Hippo signaling pathway -fly;ko04392 Hippo signaling pathway - multiple species","-"]
["STMN1",95.224159,36.357803,-1.389062617,{"v":5.56e-116,"d":"5.56E-116"},{"v":4.14e-115,"d":"4.14E-115"},"down","STMN1","stathmin 1","GO:0031110;GO:0005515;GO:0005737;GO:0005856;GO:0005874;GO:0007019;GO:0015631;GO:0031110;GO:0031175;GO:0043005;GO:0051493","K04381-ko04010 MAPK signaling pathway;ko05206 MicroRNAs in cancer","-"]
["SHROOM2",16.4842,6.290182,-1.389910207,{"v":2.69e-207,"d":"2.69E-207"},{"v":3.06e-206,"d":"3.06E-206"},"down","SHROOM2","-","GO:0003779;GO:0005623;GO:0030864;GO:0032401;GO:0045176;GO:0051015","-","-"]
["PARM1",16.985954,6.470501,-1.392392921,{"v":1.65e-74,"d":"1.65E-74"},{"v":9.22e-74,"d":"9.22E-74"},"down","PARM1","-","GO:0005634;GO:0005769;GO:0005770;GO:0005794;GO:0005829;GO:0005886;GO:0016020;GO:0016021;GO:0043231","-","-"]
["ITGAV",41.547657,15.825107,-1.392551867,{"v":5.35e-197,"d":"5.35E-197"},{"v":5.76e-196,"d":"5.76E-196"},"down","ITGAV","integrin subunit alpha V","GO:0001525;GO:0001568;GO:0001846;GO:0001968;GO:0002020;GO:0005080;GO:0005178;GO:0005245;GO:0005829;GO:0005886;GO:0005925;GO:0007155;GO:0007160;GO:0007229;GO:0008284;GO:0008305;GO:0009897;GO:0009986;GO:0010745;GO:0010888;GO:0016020;GO:0016021;GO:0017134;GO:0019960;GO:0030054;GO:0030335;GO:0031258;GO:0031527;GO:0031528;GO:0031589;GO:0031994;GO:0032369;GO:0032587;GO:0033627;GO:0033690;GO:0034113;GO:0034446;GO:0034683;GO:0034684;GO:0034685;GO:0034686;GO:0035867;GO:0035868;GO:0035987;GO:0038027;GO:0038044;GO:0038132;GO:0043277;GO:0045715;GO:0045785;GO:0046718;GO:0046872;GO:0050748;GO:0050764;GO:0050840;GO:0050919;GO:0070371;GO:0070588;GO:0097192;GO:1990430;GO:2000536;GO:2001237","K06487-ko04151 PI3K-Akt signaling pathway;ko04512 ECM-receptor interaction;ko04514 Cell adhesion molecules (CAMs);ko04145 Phagosome;ko04810 Regulation of actin cytoskeleton;ko04510 Focal adhesion;ko04919 Thyroid hormone signaling pathway;ko05200 Pathways in cancer;ko05205 Proteoglycans in cancer;ko05222 Small cell lung cancer;ko05410 Hypertrophic cardiomyopathy (HCM);ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC);ko05414 Dilated cardiomyopathy (DCM)","KOG3637-Vitronectin receptor, alpha subunit[W]"]
["ANO1",103.83419,39.40588,-1.397798741,0,0,"down","ANO1","-","GO:0005227;GO:0005229;GO:0005254;GO:0005886;GO:0006812;GO:0006821;GO:0015111;GO:0015705;GO:0016020;GO:0016021;GO:0016324;GO:0034605;GO:0035774;GO:0046983;GO:1902476","-","KOG2514-Uncharacterized conserved protein[S]"]
["UBE2G2",59.8927,22.713896,-1.398804986,{"v":3.28e-255,"d":"3.28E-255"},{"v":4.37e-254,"d":"4.37E-254"},"down","UBE2G2","ubiquitin conjugating enzyme E2 G2","GO:0000166;GO:0000209;GO:0004842;GO:0005524;GO:0005737;GO:0005783;GO:0005829;GO:0006511;GO:0016740;GO:0018279;GO:0030433;GO:0031625;GO:0035458;GO:0042802;GO:0044257;GO:0061630;GO:0061631;GO:0070936;GO:1904153","K04555-ko04141 Protein processing in endoplasmic reticulum;ko04120 Ubiquitin mediated proteolysis;ko05012 Parkinson's disease","KOG0426-Ubiquitin-protein ligase[O]"]
["B3GNT2",67.165665,25.457096,-1.399656063,{"v":8.27e-259,"d":"8.27E-259"},{"v":1.12e-257,"d":"1.12E-257"},"down","B3GNT2","UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2","GO:0000139;GO:0005794;GO:0006486;GO:0007411;GO:0007608;GO:0008378;GO:0008532;GO:0016020;GO:0016021;GO:0016740;GO:0016757;GO:0030311;GO:1990830","K00741-ko00533 Glycosaminoglycan biosynthesis - keratan sulfate;ko00601 Glycosphingolipid biosynthesis - lacto and neolacto series","KOG2287-Galactosyltransferases[G]"]
["SLC37A1",24.02487,9.103268,-1.400072165,{"v":1.33e-111,"d":"1.33E-111"},{"v":9.62e-111,"d":"9.62E-111"},"down","SLC37A1","-","GO:0015760;GO:0016020;GO:0016021;GO:0022857;GO:0030176;GO:0035435;GO:0055085;GO:0061513","-","KOG2533-Permease of the major facilitator superfamily[G]"]
["ARL15",20.27352,7.679831,-1.40045013,{"v":6.55e-146,"d":"6.55E-146"},{"v":5.71e-145,"d":"5.71E-145"},"down","ARL15","-","GO:0000166;GO:0005525;GO:0005622","-","KOG0071-GTP-binding ADP-ribosylation factor Arf6 (dArf3)[U]"]
["STARD4",15.005146,5.682715,-1.400805088,{"v":2.95e-99,"d":"2.95E-99"},{"v":1.97e-98,"d":"1.97E-98"},"down","STARD4","StAR related lipid transfer domain containing 4","GO:0005739;GO:0008289;GO:0010873;GO:0010879;GO:0015485;GO:0017127;GO:0031410;GO:0032367;GO:0070508;GO:0070859","-","KOG3845-MLN, STAR and related lipid-binding proteins[I]"]
["PGAP1",14.880245,5.625757,-1.403279137,{"v":1.36e-124,"d":"1.36E-124"},{"v":1.06e-123,"d":"1.06E-123"},"down","PGAP1","-","GO:0005783;GO:0005789;GO:0015031;GO:0016020;GO:0016021;GO:0016787;GO:0016788","K05294-ko00563 Glycosylphosphatidylinositol(GPI)-anchor biosynthesis","KOG3724-Negative regulator of COPII vesicle formation[U]"]
["STYK1",64.291351,24.305267,-1.403355685,0,0,"down","STYK1","-","GO:0004672;GO:0004715;GO:0005102;GO:0005524;GO:0005886;GO:0006468;GO:0006935;GO:0007155;GO:0007173;GO:0016020;GO:0016021;GO:0016477;GO:0030154;GO:0031234;GO:0038083;GO:0042127;GO:0043304;GO:0045087","-","KOG0200-Fibroblast/platelet-derived growth factor receptor and related receptor tyrosine kinases[T]"]
["RAB41",15.982271,6.041715,-1.403442387,{"v":2.09e-66,"d":"2.09E-66"},{"v":1.1e-65,"d":"1.10E-65"},"down","RAB41","-","GO:0003924;GO:0005525;GO:0005794;GO:0005829;GO:0006890;GO:0006891;GO:0042147","-","-"]
["XYLB",17.665987,6.677544,-1.403584873,0.000434537,0.000694079,"down","XYLB","-","GO:0004856;GO:0005737;GO:0005975;GO:0005997;GO:0016773;GO:0046835","K00854-ko00040 Pentose and glucuronate interconversions","KOG2531-Sugar (pentulose and hexulose) kinases[G]"]
["LOC101747877",7.648283,2.890896,-1.403619198,{"v":1.19e-87,"d":"1.19E-87"},{"v":7.33e-87,"d":"7.33E-87"},"down","LOC101747877","-","-","-","-"]
["DAAM1",28.651104,10.828347,-1.403777705,{"v":9.07e-237,"d":"9.07E-237"},{"v":1.14e-235,"d":"1.14E-235"},"down","DAAM1","dishevelled associated activator of morphogenesis 1","GO:0001725;GO:0003779;GO:0005829;GO:0005886;GO:0016043;GO:0017048;GO:0030036;GO:0031514;GO:0036064;GO:0042802","K04512-ko04310 Wnt signaling pathway","[KOG1924-RhoA GTPase effector DIA/Diaphanous[TZ], KOG1923-Rac1 GTPase effector FRL[TZ]]"]
["ASIC1",7.285542,2.751332,-1.404906066,{"v":4.94e-45,"d":"4.94E-45"},{"v":2.12e-44,"d":"2.12E-44"},"down","ASIC1","acid sensing ion channel subunit 1","GO:0001662;GO:0001975;GO:0005261;GO:0005272;GO:0005515;GO:0005794;GO:0005886;GO:0005887;GO:0006811;GO:0006812;GO:0006814;GO:0007613;GO:0008306;GO:0010447;GO:0015280;GO:0016020;GO:0016021;GO:0022839;GO:0034220;GO:0035725;GO:0042391;GO:0042802;GO:0044736;GO:0045202;GO:0046929;GO:0050915;GO:0070207;GO:0070588;GO:0071467;GO:0004367;GO:0005975;GO:0006072;GO:0009331;GO:0016491;GO:0016616;GO:0042803;GO:0046168;GO:0051287;GO:0055114","-","KOG4294-Non voltage-gated ion channels (DEG/ENaC family)[PT]"]
["C3H1ORF131",82.301567,31.059437,-1.405888221,{"v":3.13e-121,"d":"3.13E-121"},{"v":2.39e-120,"d":"2.39E-120"},"down","C3H1ORF131","-","-","-","-"]
["ENTPD1",63.96199,24.129883,-1.406393905,{"v":2.97e-279,"d":"2.97E-279"},{"v":4.24e-278,"d":"4.24E-278"},"down","ENTPD1","ectonucleoside triphosphate diphosphohydrolase 1","GO:0016020;GO:0016021;GO:0016787","K01510-ko00230 Purine metabolism;ko00240 Pyrimidine metabolism;ko05169 Epstein-Barr virus infection","KOG1386-Nucleoside phosphatase[F]"]
["VIPR2",29.095547,10.961164,-1.408397359,{"v":3.18e-69,"d":"3.18E-69"},{"v":1.71e-68,"d":"1.71E-68"},"down","VIPR2","vasoactive intestinal peptide receptor 2","-","K04590-ko04024 cAMP signaling pathway;ko04080 Neuroactive ligand-receptor interaction","KOG4564-Adenylate cyclase-coupled calcitonin receptor[T]"]
["SPC25",11.487363,4.32743,-1.408465268,{"v":8.81e-23,"d":"8.81E-23"},{"v":2.7e-22,"d":"2.70E-22"},"down","SPC25","SPC25, NDC80 kinetochore complex component","GO:0000777;GO:0005829;GO:0007052;GO:0007059;GO:0031262","-","KOG4657-Uncharacterized conserved protein[S]"]
["ITGB3",8.701744,3.276169,-1.409294794,{"v":7.74e-44,"d":"7.74E-44"},{"v":3.27e-43,"d":"3.27E-43"},"down","ITGB3","integrin subunit beta 3","GO:0001954;GO:0005080;GO:0005178;GO:0007044;GO:0007155;GO:0007160;GO:0007229;GO:0008305;GO:0009897;GO:0009986;GO:0010628;GO:0010763;GO:0016020;GO:0016021;GO:0016324;GO:0019899;GO:0030334;GO:0030335;GO:0032956;GO:0033690;GO:0035866;GO:0036120;GO:0042802;GO:0043277;GO:0048008;GO:0048146;GO:0061097;GO:0070527;GO:0071133;GO:0098978;GO:0099699;GO:1900026;GO:1903053;GO:2000406","K06493-ko04015 Rap1 signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04512 ECM-receptor interaction;ko04145 Phagosome;ko04810 Regulation of actin cytoskeleton;ko04510 Focal adhesion;ko04640 Hematopoietic cell lineage;ko04611 Platelet activation;ko04919 Thyroid hormone signaling pathway;ko04380 Osteoclast differentiation;ko05206 MicroRNAs in cancer;ko05205 Proteoglycans in cancer;ko05410 Hypertrophic cardiomyopathy (HCM);ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC);ko05414 Dilated cardiomyopathy (DCM)","KOG1226-Integrin beta subunit (N-terminal portion of extracellular region)[TW]"]
["RASGRF2",5.989404,2.25471,-1.409470562,{"v":2.25e-57,"d":"2.25E-57"},{"v":1.09e-56,"d":"1.09E-56"},"down","RASGRF2","-","GO:0005085;GO:0005088;GO:0005089;GO:0005783;GO:0007264;GO:0034976;GO:0035023;GO:0046578","K12326-ko04014 Ras signaling pathway;ko04010 MAPK signaling pathway","KOG3417-Ras1 guanine nucleotide exchange factor[T]"]
["PLEKHG5",37.245949,14.020347,-1.409561465,{"v":1.2e-197,"d":"1.20E-197"},{"v":1.29e-196,"d":"1.29E-196"},"down","PLEKHG5","-","GO:0005089;GO:0035023","-","KOG3521-Predicted guanine nucleotide exchange factor[T]"]
["GJC2",42.29747,15.879716,-1.413386261,{"v":5.23e-211,"d":"5.23E-211"},{"v":6.02e-210,"d":"6.02E-210"},"down","GJC2","gap junction protein gamma 2","GO:0005243;GO:0005886;GO:0005921;GO:0005922;GO:0007154;GO:0007267;GO:0009636;GO:0010644;GO:0016020;GO:0016021;GO:0030054;GO:0043209;GO:0055085;GO:1903763","-","-"]
["IL18R1",5.577717,2.091968,-1.414813954,{"v":7.42e-18,"d":"7.42E-18"},{"v":2.05e-17,"d":"2.05E-17"},"down","IL18R1","interleukin 18 receptor 1","GO:0004908;GO:0007165;GO:0016020;GO:0016021;GO:0030101;GO:0032729;GO:0035655;GO:0042007;GO:0042008;GO:0045063;GO:0051092;GO:0120163;GO:1901224;GO:2000556","K05173-ko04668 TNF signaling pathway;ko04060 Cytokine-cytokine receptor interaction;ko05321 Inflammatiory bowel disease (IBD)","-"]
["IFT57",52.746456,19.774122,-1.415460525,{"v":1.89e-140,"d":"1.89E-140"},{"v":1.6e-139,"d":"1.60E-139"},"down","IFT57","-","GO:0001843;GO:0001947;GO:0005794;GO:0005813;GO:0005929;GO:0005930;GO:0006915;GO:0006919;GO:0007224;GO:0030992;GO:0032391;GO:0036064;GO:0042073;GO:0042981;GO:0044292;GO:0044458;GO:0050680;GO:0060271;GO:0060972;GO:1905515","-","KOG0972-Huntingtin interacting protein 1 (Hip1) interactor Hippi[T]"]
["LAD1",49.352306,18.489914,-1.416378982,{"v":2.9e-156,"d":"2.90E-156"},{"v":2.65e-155,"d":"2.65E-155"},"down","LAD1","-","GO:0005198;GO:0015629","-","-"]
["IKZF2",19.053871,7.131718,-1.417762564,{"v":4.87e-273,"d":"4.87E-273"},{"v":6.82e-272,"d":"6.82E-272"},"down","IKZF2","IKAROS family zinc finger 2","GO:0003676;GO:0005634;GO:0042803;GO:0045944;GO:0046982","-","KOG2462-C2H2-type Zn-finger protein[K]"]
["DGKA",14.611548,5.468859,-1.417797259,{"v":1.95e-55,"d":"1.95E-55"},{"v":9.32e-55,"d":"9.32E-55"},"down","DGKA","-","GO:0000166;GO:0003951;GO:0004143;GO:0005509;GO:0005524;GO:0005543;GO:0005829;GO:0005886;GO:0006654;GO:0007165;GO:0007205;GO:0008152;GO:0016301;GO:0016310;GO:0016740;GO:0035556;GO:0046339;GO:0046486;GO:0046834","K00901-ko00561 Glycerolipid metabolism;ko00564 Glycerophospholipid metabolism;ko04070 Phosphatidylinositol signaling system;ko04072 Phospholipase D signaling pathway;ko05231 Choline metabolism in cancer","KOG1169-Diacylglycerol kinase[IT]"]
["GFPT1",145.003922,54.260399,-1.418120361,0,0,"down","GFPT1","glutamine--fructose-6-phosphate transaminase 1","GO:0004360;GO:0097367;GO:1901135;GO:1901137;GO:0004360;GO:0006002;GO:0006047;GO:0006487;GO:0032922;GO:0097367;GO:1901135;GO:1901137","K00820-ko00520 Amino sugar and nucleotide sugar metabolism;ko00250 Alanine, aspartate and glutamate metabolism;ko04931 Insulin resistance","KOG1268-Glucosamine 6-phosphate synthetases, contain amidotransferase and phosphosugar isomerase domains[M]"]
["ALPL",26.45429,9.891998,-1.419167845,{"v":1.48e-67,"d":"1.48E-67"},{"v":7.82e-67,"d":"7.82E-67"},"down","ALPL","alkaline phosphatase, liver/bone/kidney","GO:0003824;GO:0004035;GO:0005886;GO:0008152;GO:0016020;GO:0016311;GO:0016787;GO:0016791;GO:0031225;GO:0046872;GO:0065010","K01077-ko00790 Folate biosynthesis;ko00627 Aminobenzoate degradation;ko02020 Two-component system","KOG4126-Alkaline phosphatase[P]"]
["ADGRD1",30.011524,11.206751,-1.421148501,0,0,"down","ADGRD1","-","GO:0004888;GO:0004930;GO:0005622;GO:0005886;GO:0007166;GO:0007186;GO:0007189;GO:0016020;GO:0016021","-","-"]
["SDC1",156.277802,58.352703,-1.421241479,0,0,"down","SDC1","-","GO:0008022;GO:0009897;GO:0009986;GO:0016020;GO:0016021;GO:0016477;GO:0042060;GO:0042802;GO:0048627;GO:0055002;GO:0060070;GO:1903543;GO:1903553","K06257-ko04512 ECM-receptor interaction;ko04514 Cell adhesion molecules (CAMs);ko05205 Proteoglycans in cancer;ko05144 Malaria","-"]
["C5NT1AL",11.422896,4.260087,-1.422973659,{"v":1.12e-32,"d":"1.12E-32"},{"v":4.1e-32,"d":"4.10E-32"},"down","C5NT1AL","-","GO:0000166;GO:0000287;GO:0005737;GO:0008253;GO:0009117;GO:0016311","K01081-ko00230 Purine metabolism;ko00240 Pyrimidine metabolism;ko00760 Nicotinate and nicotinamide metabolism","-"]
["UGT8",114.843597,42.818707,-1.423357287,{"v":5.46e-295,"d":"5.46E-295"},{"v":8.19e-294,"d":"8.19E-294"},"down","UGT8","UDP glycosyltransferase 8","GO:0002175;GO:0007010;GO:0008152;GO:0015020;GO:0016020;GO:0016021;GO:0016740;GO:0016757;GO:0016758;GO:0030913;GO:0043231;GO:0048812","K04628-ko00565 Ether lipid metabolism;ko00600 Sphingolipid metabolism","KOG1192-UDP-glucuronosyl and UDP-glucosyl transferase[GC]"]
["UGT2A1",94.223,35.036911,-1.427203681,0,0,"down","UGT2A1","-","GO:0008152;GO:0015020;GO:0016020;GO:0016021;GO:0016740;GO:0016757;GO:0016758;GO:0043231","K00699-ko00040 Pentose and glucuronate interconversions;ko00053 Ascorbate and aldarate metabolism;ko00500 Starch and sucrose metabolism;ko00140 Steroid hormone biosynthesis;ko00830 Retinol metabolism;ko00860 Porphyrin and chlorophyll metabolism;ko00980 Metabolism of xenobiotics by cytochrome P450;ko00982 Drug metabolism - cytochrome P450;ko00983 Drug metabolism - other enzymes;ko05204 Chemical carcinogenesis","-"]
["FDPS",63.782619,23.699144,-1.428328387,{"v":4.74e-121,"d":"4.74E-121"},{"v":3.62e-120,"d":"3.62E-120"},"down","FDPS","-","GO:0004161;GO:0004337;GO:0005654;GO:0005737;GO:0005829;GO:0006629;GO:0006694;GO:0006695;GO:0008202;GO:0008203;GO:0008299;GO:0016126;GO:0016740;GO:0033384;GO:0045337;GO:0046872","K00787-ko00900 Terpenoid backbone biosynthesis;ko05166 HTLV-I infection;ko05164 Influenza A","KOG0711-Polyprenyl synthetase[H]"]
["TACSTD2",5.061622,1.880227,-1.428692922,{"v":3.02e-08,"d":"3.02E-08"},{"v":6.12e-08,"d":"6.12E-08"},"down","TACSTD2","tumor-associated calcium signal transducer 2","GO:0005615;GO:0005634;GO:0005887;GO:0016020;GO:0016021;GO:0098609;GO:2000738","-","-"]
["FAM65B",18.845783,6.998117,-1.429203047,{"v":1.41e-129,"d":"1.41E-129"},{"v":1.13e-128,"d":"1.13E-128"},"down","FAM65B","family with sequence similarity 65, member B","GO:0007605;GO:0048741","-","-"]
["KDM1B",37.160053,13.796734,-1.429425771,{"v":1.24e-291,"d":"1.24E-291"},{"v":1.84e-290,"d":"1.84E-290"},"down","KDM1B","-","GO:0000786;GO:0003677;GO:0005634;GO:0006349;GO:0008270;GO:0016491;GO:0034648;GO:0034649;GO:0034720;GO:0042393;GO:0043046;GO:0044030;GO:0050660;GO:0055114;GO:0071949","-","KOG0029-Amine oxidase[Q]"]
["TXNDC17",308.481201,114.26265,-1.432828679,{"v":4.18e-291,"d":"4.18E-291"},{"v":6.18e-290,"d":"6.18E-290"},"down","TXNDC17","-","GO:0004601;GO:0005829;GO:0033209;GO:0047134;GO:0055114;GO:0098869","-","KOG3425-Uncharacterized conserved protein[S]"]
["NANS",92.655945,34.312199,-1.433161957,0,0,"down","NANS","N-acetylneuraminate synthase","GO:0003824;GO:0005829;GO:0016051;GO:0047444","K05304-ko00520 Amino sugar and nucleotide sugar metabolism","-"]
["KNSTRN",9.979734,3.693394,-1.434054189,{"v":4.32e-17,"d":"4.32E-17"},{"v":1.17e-16,"d":"1.17E-16"},"down","KNSTRN","kinetochore-localized astrin/SPAG5 binding protein","GO:0000070;GO:0000776;GO:0005829;GO:0007051;GO:0007059;GO:0015630;GO:0035371;GO:0051988;GO:0072686","-","-"]
["FZD7",27.62805,10.209618,-1.436204852,{"v":4.66e-122,"d":"4.66E-122"},{"v":3.58e-121,"d":"3.58E-121"},"down","FZD7","frizzled class receptor 7","GO:0004888;GO:0004930;GO:0005768;GO:0005886;GO:0007165;GO:0007166;GO:0007186;GO:0007275;GO:0010008;GO:0016020;GO:0016021;GO:0016055;GO:0017147;GO:0035567;GO:0042813;GO:0060070","K02432-ko04310 Wnt signaling pathway;ko04390 Hippo signaling pathway;ko04150 mTOR signaling pathway;ko04550 Signaling pathways regulating pluripotency of stem cells;ko04916 Melanogenesis;ko05200 Pathways in cancer;ko05205 Proteoglycans in cancer;ko05217 Basal cell carcinoma;ko05224 Breast cancer;ko05166 HTLV-I infection","KOG3577-Smoothened and related G-protein-coupled receptors[T]"]
["ERBB3",37.629379,13.895344,-1.43725793,{"v":1.63e-248,"d":"1.63E-248"},{"v":2.13e-247,"d":"2.13E-247"},"down","ERBB3","erb-b2 receptor tyrosine kinase 3","GO:0000166;GO:0003197;GO:0004672;GO:0004713;GO:0004714;GO:0005524;GO:0005615;GO:0005622;GO:0006468;GO:0007162;GO:0007165;GO:0007169;GO:0007422;GO:0009968;GO:0010628;GO:0014037;GO:0014065;GO:0016020;GO:0016021;GO:0016323;GO:0016324;GO:0016328;GO:0018108;GO:0019838;GO:0021545;GO:0030296;GO:0031625;GO:0038132;GO:0042127;GO:0042802;GO:0043235;GO:0043524;GO:0046982;GO:0051048;GO:0051402;GO:0055025;GO:0061098;GO:0070886;GO:0097192","K05084-ko04012 ErbB signaling pathway;ko04020 Calcium signaling pathway;ko04144 Endocytosis;ko05206 MicroRNAs in cancer;ko05205 Proteoglycans in cancer;ko01521 EGFR tyrosine kinase inhibitor resistance","KOG1025-Epidermal growth factor receptor EGFR and related tyrosine kinases[T]"]
["LOC107049632",12.200177,4.505082,-1.437276808,{"v":2.24e-22,"d":"2.24E-22"},{"v":6.82e-22,"d":"6.82E-22"},"down","LOC107049632","-","-","-","-"]
["SLIT1",16.658413,6.150995,-1.437359257,{"v":6.24e-150,"d":"6.24E-150"},{"v":5.54e-149,"d":"5.54E-149"},"down","SLIT1","slit guidance ligand 1","GO:0005509;GO:0005615;GO:0005622;GO:0005623;GO:0007097;GO:0007409;GO:0007411;GO:0008045;GO:0021772;GO:0022028;GO:0022029;GO:0031290;GO:0033563;GO:0045661;GO:0048495;GO:0048812;GO:0048846;GO:0050919;GO:0051493;GO:0061561;GO:0061563;GO:0071896;GO:0098743;GO:2000290;GO:2001266","-","-"]
["CERS3",26.156851,9.63527,-1.440791867,{"v":2.24e-40,"d":"2.24E-40"},{"v":9.11e-40,"d":"9.11E-40"},"down","CERS3","-","GO:0003677;GO:0005634;GO:0005783;GO:0016020;GO:0016021;GO:0030148;GO:0030216;GO:0046513;GO:0050291;GO:0050890","-","KOG1607-Protein transporter of the TRAM (translocating chain-associating membrane) superfamily[U]"]
["MDK",17.481726,6.41757,-1.445748599,{"v":1.02e-24,"d":"1.02E-24"},{"v":3.25e-24,"d":"3.25E-24"},"down","MDK","midkine (neurite growth-promoting factor 2)","GO:0001662;GO:0007614;GO:0008083;GO:0008201;GO:0009611;GO:0010469;GO:0021542;GO:0021681;GO:0021766;GO:0021987;GO:0030421;GO:0043524;GO:0045893;GO:0050795;GO:1901215","-","-"]
["MICALL1",74.174744,27.228228,-1.445824947,0,0,"down","MICALL1","MICAL like 1","GO:0005622;GO:0005770;GO:0006612;GO:0006897;GO:0006898;GO:0017137;GO:0019898;GO:0031175;GO:0032456;GO:0032458;GO:0036010;GO:0042802;GO:0046872;GO:0055038;GO:0070300;GO:0097320;GO:1990126","-","KOG0035-Ca2+-binding actin-bundling protein (actinin), alpha chain (EF-Hand protein superfamily)[Z]"]
["SLC22A3",15.393412,5.61201,-1.45572356,{"v":5.51e-45,"d":"5.51E-45"},{"v":2.36e-44,"d":"2.36E-44"},"down","SLC22A3","-","GO:0005215;GO:0005887;GO:0008514;GO:0015101;GO:0015651;GO:0015695;GO:0015697;GO:0015711;GO:0015844;GO:0015872;GO:0016020;GO:0016021;GO:0022857;GO:0032098;GO:0051608;GO:0051615;GO:0055085","-","KOG0255-Synaptic vesicle transporter SVOP and related transporters (major facilitator superfamily)[R]"]
["PLBD1",53.550678,19.485876,-1.458476051,{"v":2.24e-226,"d":"2.24E-226"},{"v":2.72e-225,"d":"2.72E-225"},"down","PLBD1","-","GO:0005615;GO:0006629;GO:0016042;GO:0016787","-","KOG3774-Uncharacterized conserved protein Lama[T]"]
["SYNCRIP",54.556702,19.850918,-1.458550709,{"v":1.68e-192,"d":"1.68E-192"},{"v":1.78e-191,"d":"1.78E-191"},"down","SYNCRIP","synaptotagmin binding cytoplasmic RNA interacting protein","GO:0003676;GO:0003723;GO:0005737;GO:0008143;GO:0017148;GO:0070934;GO:0070937;GO:0071013;GO:0071204;GO:0071346;GO:0097452;GO:1990904","-","KOG0117-Heterogeneous nuclear ribonucleoprotein R (RRM superfamily)[A]"]
["ITIH5",27.307384,9.931151,-1.459258275,{"v":1.44e-210,"d":"1.44E-210"},{"v":1.65e-209,"d":"1.65E-209"},"down","ITIH5","-","GO:0004867;GO:0010951;GO:0030212","-","KOG2353-L-type voltage-dependent Ca2+ channel, alpha2/delta subunit[PT]"]
["KRT19",471.10675,170.80072,-1.463739946,0,0,"down","KRT19","keratin 19","GO:0005198;GO:0005882;GO:0005886;GO:0007219;GO:0008307;GO:0016327;GO:0030018;GO:0042383;GO:0043034;GO:0043627;GO:0045214;GO:0071944;GO:1990357","-","KOG0977-Nuclear envelope protein lamin, intermediate filament superfamily[DY]"]
["MARCO",6.100744,2.209607,-1.465195398,{"v":2.73e-17,"d":"2.73E-17"},{"v":7.46e-17,"d":"7.46E-17"},"down","MARCO","macrophage receptor with collagenous structure","GO:0001664;GO:0005044;GO:0006897;GO:0006898;GO:0016020;GO:0016021;GO:0043277","K13884-ko04145 Phagosome","KOG3546-Collagens (type XV)[W]"]
["LOC107053677",11.909909,4.312189,-1.465670073,{"v":1.56e-24,"d":"1.56E-24"},{"v":4.96e-24,"d":"4.96E-24"},"down","LOC107053677","-","-","-","-"]
["PTCH1",6.554146,2.371197,-1.466792283,{"v":1.72e-61,"d":"1.72E-61"},{"v":8.61e-61,"d":"8.61E-61"},"down","PTCH1","patched 1","GO:0000122;GO:0001658;GO:0001709;GO:0001841;GO:0001843;GO:0003007;GO:0005113;GO:0005119;GO:0005794;GO:0005886;GO:0005901;GO:0005929;GO:0007165;GO:0007224;GO:0007346;GO:0007389;GO:0007420;GO:0008158;GO:0008201;GO:0008285;GO:0008544;GO:0008589;GO:0009887;GO:0009953;GO:0009957;GO:0010157;GO:0010875;GO:0015485;GO:0016020;GO:0016021;GO:0016485;GO:0021522;GO:0021532;GO:0021904;GO:0021997;GO:0030326;GO:0030332;GO:0030496;GO:0032880;GO:0035108;GO:0035137;GO:0040008;GO:0040015;GO:0042127;GO:0042593;GO:0043231;GO:0043433;GO:0043616;GO:0044877;GO:0045606;GO:0045668;GO:0045879;GO:0045892;GO:0045893;GO:0048471;GO:0048568;GO:0050680;GO:0051782;GO:0060037;GO:0060831;GO:0061005;GO:0061053;GO:0071397;GO:0072001;GO:0072203;GO:0072659;GO:0097108;GO:0005887;GO:0007224;GO:0008158;GO:0016020;GO:0016021","K06225-ko04340 Hedgehog signaling pathway;ko04341 Hedgehog signaling pathway - Fly;ko04024 cAMP signaling pathway;ko04360 Axon guidance;ko05200 Pathways in cancer;ko05205 Proteoglycans in cancer;ko05217 Basal cell carcinoma","KOG1935-Membrane protein Patched/PTCH[T]"]
["LPAR5",7.914567,2.847531,-1.474798876,{"v":5.76e-23,"d":"5.76E-23"},{"v":1.77e-22,"d":"1.77E-22"},"down","LPAR5","-","-","K08390-ko04015 Rap1 signaling pathway;ko04072 Phospholipase D signaling pathway;ko04151 PI3K-Akt signaling pathway;ko05200 Pathways in cancer","KOG4219-G protein-coupled receptor[T]"]
["EZH2",18.577881,6.682653,-1.475093088,{"v":1.64e-80,"d":"1.64E-80"},{"v":9.6e-80,"d":"9.60E-80"},"down","EZH2","-","GO:0000122;GO:0000790;GO:0000978;GO:0000979;GO:0001932;GO:0003682;GO:0003723;GO:0005634;GO:0006306;GO:0006357;GO:0008284;GO:0010468;GO:0010718;GO:0014013;GO:0014834;GO:0014898;GO:0016279;GO:0016571;GO:0018024;GO:0021695;GO:0031490;GO:0034244;GO:0035098;GO:0035984;GO:0036333;GO:0042054;GO:0042127;GO:0042752;GO:0043021;GO:0043406;GO:0043433;GO:0043547;GO:0043565;GO:0045120;GO:0045605;GO:0045814;GO:0045892;GO:0046976;GO:0048387;GO:0050767;GO:0051154;GO:0070301;GO:0070314;GO:0070734;GO:0070878;GO:0071168;GO:0071902;GO:0097421;GO:0098532;GO:1902808;GO:1904772;GO:1990841;GO:2000134","K11430-ko05206 MicroRNAs in cancer","KOG1079-Transcriptional repressor EZH1[K]"]
["PLD6",5.794081,2.081499,-1.476956988,{"v":2.83e-18,"d":"2.83E-18"},{"v":7.91e-18,"d":"7.91E-18"},"down","PLD6","-","-","-","-"]
["HABP4",31.688225,11.382895,-1.477079327,{"v":3.91e-84,"d":"3.91E-84"},{"v":2.35e-83,"d":"2.35E-83"},"down","HABP4","hyaluronan binding protein 4","GO:0003723;GO:0005634;GO:0005730;GO:0005737;GO:0006351;GO:0006355;GO:0006397;GO:0006417;GO:0008380;GO:0010494;GO:0015030;GO:0016528;GO:0016604;GO:0016607;GO:0033120;GO:0043392;GO:0045948;GO:0097504","-","-"]
["CA9",57.003487,20.464979,-1.477892988,{"v":1.77e-118,"d":"1.77E-118"},{"v":1.33e-117,"d":"1.33E-117"},"down","CA9","-","GO:0002009;GO:0004089;GO:0005886;GO:0008270;GO:0016020;GO:0016021;GO:0046872;GO:0046903","K01672-ko00910 Nitrogen metabolism","KOG0382-Carbonic anhydrase[R]"]
["PLXDC1",26.935486,9.655584,-1.48007267,{"v":1.1e-158,"d":"1.10E-158"},{"v":1.02e-157,"d":"1.02E-157"},"down","PLXDC1","-","GO:0001525;GO:0005737;GO:0005886;GO:0016020;GO:0016021;GO:0043235","-","KOG3848-Extracellular protein TEM7, contains PSI domain (tumor endothelial marker in humans)[W]"]
["CENPQ",11.352559,4.06903,-1.480260712,{"v":2.22e-24,"d":"2.22E-24"},{"v":7.03e-24,"d":"7.03E-24"},"down","CENPQ","centromere protein Q","GO:0000775;GO:0005634;GO:0005694;GO:0016020;GO:0016021;GO:0051310;GO:1905342","-","-"]
["TRIM35",50.676258,18.159363,-1.480596402,{"v":4.4e-137,"d":"4.40E-137"},{"v":3.67e-136,"d":"3.67E-136"},"down","TRIM35","-","GO:0043065;GO:0045087;GO:0045930;GO:1902187","-","KOG2177-Predicted E3 ubiquitin ligase[O]"]
["KIFC1L",12.373094,4.43042,-1.481690927,{"v":1.85e-42,"d":"1.85E-42"},{"v":7.66e-42,"d":"7.66E-42"},"down","KIFC1L","-","GO:0000166;GO:0003774;GO:0003777;GO:0005524;GO:0005874;GO:0007018;GO:0008017;GO:0000166;GO:0003774;GO:0003777;GO:0005524;GO:0005874;GO:0007018;GO:0008017","-","-"]
["SLC4A4",19.545389,6.998219,-1.48176858,{"v":4.81e-215,"d":"4.81E-215"},{"v":5.61e-214,"d":"5.61E-214"},"down","SLC4A4","-","GO:0005452;GO:0006811;GO:0006814;GO:0006820;GO:0008509;GO:0008510;GO:0015698;GO:0015701;GO:0016020;GO:0016021;GO:0016323;GO:0098656","-","KOG1172-Na+-independent Cl/HCO3 exchanger AE1 and related transporters (SLC4 family)[P]"]
["EPHX1L",153.447296,54.9338,-1.481977226,0,0,"down","EPHX1L","-","GO:0003824;GO:0016020;GO:0016021;GO:0033961","K01253-ko00980 Metabolism of xenobiotics by cytochrome P450;ko04976 Bile secretion;ko05204 Chemical carcinogenesis","-"]
["FAM180B",7.906691,2.830571,-1.481980932,{"v":7.75e-65,"d":"7.75E-65"},{"v":3.99e-64,"d":"3.99E-64"},"down","FAM180B","-","-","-","-"]
["CAB39L",139.2939,49.839245,-1.482777962,0,0,"down","CAB39L","calcium binding protein 39 like","-","K08272-ko04152 AMPK signaling pathway;ko04150 mTOR signaling pathway","KOG1566-Conserved protein Mo25[S]"]
["LOC107054809",10.779388,3.831874,-1.492153243,{"v":8.91e-59,"d":"8.91E-59"},{"v":4.38e-58,"d":"4.38E-58"},"down","LOC107054809","-","-","-","-"]
["CNNM1",7.34091,2.608802,-1.492571463,{"v":3.36e-29,"d":"3.36E-29"},{"v":1.16e-28,"d":"1.16E-28"},"down","CNNM1","-","-","-","KOG2118-Predicted membrane protein, contains two CBS domains[S]"]
["SHH",6.688159,2.374874,-1.493758173,{"v":5.08e-17,"d":"5.08E-17"},{"v":1.38e-16,"d":"1.38E-16"},"down","SHH","sonic hedgehog","GO:0000122;GO:0001525;GO:0001569;GO:0001570;GO:0001656;GO:0001658;GO:0001708;GO:0001709;GO:0001755;GO:0001822;GO:0001895;GO:0001944;GO:0001947;GO:0002052;GO:0002053;GO:0002076;GO:0002320;GO:0003140;GO:0003406;GO:0003408;GO:0003430;GO:0005113;GO:0005509;GO:0005539;GO:0005576;GO:0005615;GO:0005622;GO:0005886;GO:0006355;GO:0006508;GO:0006897;GO:0007224;GO:0007228;GO:0007267;GO:0007275;GO:0007368;GO:0007389;GO:0007398;GO:0007405;GO:0007411;GO:0007417;GO:0007442;GO:0007507;GO:0007596;GO:0008209;GO:0008233;GO:0008270;GO:0008283;GO:0008284;GO:0009880;GO:0009888;GO:0009949;GO:0009951;GO:0009952;GO:0009953;GO:0009986;GO:0010463;GO:0010468;GO:0010469;GO:0010628;GO:0010629;GO:0010694;GO:0010770;GO:0014003;GO:0014706;GO:0014858;GO:0014902;GO:0016015;GO:0016020;GO:0016539;GO:0016787;GO:0021508;GO:0021513;GO:0021522;GO:0021631;GO:0021794;GO:0021871;GO:0021904;GO:0021924;GO:0021930;GO:0021938;GO:0021940;GO:0021978;GO:0023052;GO:0030010;GO:0030162;GO:0030166;GO:0030177;GO:0030178;GO:0030323;GO:0030324;GO:0030326;GO:0030336;GO:0030514;GO:0030539;GO:0030850;GO:0030878;GO:0030900;GO:0030901;GO:0030902;GO:0031012;GO:0031016;GO:0032435;GO:0032526;GO:0033077;GO:0033089;GO:0033092;GO:0034244;GO:0034504;GO:0035115;GO:0035116;GO:0042127;GO:0042130;GO:0042177;GO:0042307;GO:0042481;GO:0042733;GO:0043010;GO:0043066;GO:0043237;GO:0043369;GO:0043588;GO:0045059;GO:0045060;GO:0045109;GO:0045121;GO:0045165;GO:0045445;GO:0045596;GO:0045597;GO:0045669;GO:0045880;GO:0045893;GO:0045944;GO:0046638;GO:0046639;GO:0046872;GO:0048468;GO:0048538;GO:0048546;GO:0048557;GO:0048568;GO:0048589;GO:0048598;GO:0048617;GO:0048643;GO:0048645;GO:0048646;GO:0048663;GO:0048706;GO:0048709;GO:0048714;GO:0048754;GO:0048839;GO:0048856;GO:0048859;GO:0048864;GO:0048877;GO:0051146;GO:0051155;GO:0051781;GO:0060020;GO:0060021;GO:0060059;GO:0060070;GO:0060173;GO:0060174;GO:0060425;GO:0060428;GO:0060438;GO:0060439;GO:0060441;GO:0060442;GO:0060445;GO:0060447;GO:0060458;GO:0060459;GO:0060463;GO:0060484;GO:0060516;GO:0060523;GO:0060573;GO:0060591;GO:0060662;GO:0060664;GO:0060684;GO:0060685;GO:0060738;GO:0060768;GO:0060769;GO:0060782;GO:0060783;GO:0060785;GO:0060786;GO:0060840;GO:0060916;GO:0061053;GO:0061075;GO:0061189;GO:0071285;GO:0071679;GO:0072001;GO:0072136;GO:0090090;GO:0090269;GO:0090370;GO:0097190;GO:0097264;GO:1900180;GO:1904339;GO:1905327;GO:2000062;GO:2000063;GO:2000177;GO:2000357;GO:2000358;GO:2000729;GO:2001054","K11988-ko04340 Hedgehog signaling pathway;ko04360 Axon guidance;ko05200 Pathways in cancer;ko05205 Proteoglycans in cancer;ko05217 Basal cell carcinoma","KOG3638-Sonic hedgehog and related proteins[T]"]
["FAM84B",27.042658,9.593482,-1.495110511,{"v":7.43e-268,"d":"7.43E-268"},{"v":1.03e-266,"d":"1.03E-266"},"down","FAM84B","-","-","-","-"]
["FAM134C",63.242592,22.431463,-1.49537278,{"v":7.67e-279,"d":"7.67E-279"},{"v":1.09e-277,"d":"1.09E-277"},"down","FAM134C","-","-","-","-"]
["P2RX4",92.318642,32.690205,-1.497763578,{"v":1.04e-250,"d":"1.04E-250"},{"v":1.37e-249,"d":"1.37E-249"},"down","P2RX4","purinergic receptor P2X 4","GO:0001614;GO:0004931;GO:0005216;GO:0005524;GO:0005639;GO:0005886;GO:0005887;GO:0006811;GO:0007165;GO:0008217;GO:0010524;GO:0010614;GO:0016020;GO:0016021;GO:0019722;GO:0030054;GO:0033198;GO:0034220;GO:0034405;GO:0035590;GO:0043536;GO:0045296;GO:0048471;GO:0050850;GO:0051899;GO:0055117;GO:0055119;GO:0060079;GO:0070588;GO:0071318;GO:0097190;GO:0098655;GO:0098794;GO:0099604;GO:2001028","K05218-ko04020 Calcium signaling pathway;ko04080 Neuroactive ligand-receptor interaction","-"]
["SCD",5.40215,1.91276,-1.497877834,{"v":4.65e-13,"d":"4.65E-13"},{"v":1.13e-12,"d":"1.13E-12"},"down","SCD","stearoyl-CoA desaturase","GO:0004768;GO:0005506;GO:0005730;GO:0005783;GO:0005789;GO:0006629;GO:0006633;GO:0006636;GO:0016020;GO:0016021;GO:0016491;GO:0016717;GO:0055114;GO:1903966","K00507-ko01212 Fatty acid metabolism;ko01040 Biosynthesis of unsaturated fatty acids;ko04152 AMPK signaling pathway;ko03320 PPAR signaling pathway;ko04212 Longevity regulating pathway - worm","KOG1600-Fatty acid desaturase[I]"]
["SOCS2",50.822144,17.957348,-1.500882935,{"v":8.54e-132,"d":"8.54E-132"},{"v":6.95e-131,"d":"6.95E-131"},"down","SOCS2","suppressor of cytokine signaling 2","GO:0001558;GO:0005131;GO:0005159;GO:0005737;GO:0008269;GO:0016567;GO:0032355;GO:0032870;GO:0035556;GO:0040014;GO:0040015;GO:0045666;GO:0046426;GO:0060396","K04695-ko04630 Jak-STAT signaling pathway;ko04910 Insulin signaling pathway;ko04917 Prolactin signaling pathway;ko04930 Type II diabetes mellitus","KOG4566-Cytokine-inducible SH2 protein[T]"]
["VSTM4",15.072745,5.324478,-1.501230181,{"v":6.31e-81,"d":"6.31E-81"},{"v":3.71e-80,"d":"3.71E-80"},"down","VSTM4","-","GO:0005886;GO:0016020;GO:0016021","-","-"]
["KCTD14",23.581038,8.322525,-1.502534021,{"v":5.04e-39,"d":"5.04E-39"},{"v":2e-38,"d":"2.00E-38"},"down","KCTD14","potassium channel tetramerization domain containing 14","GO:0051260","-","KOG2723-Uncharacterized conserved protein, contains BTB/POZ domain[R]"]
["SNCG",8.871543,3.130665,-1.50271591,{"v":2e-13,"d":"2.00E-13"},{"v":4.93e-13,"d":"4.93E-13"},"down","SNCG","synuclein gamma","-","-","-"]
["MEGF9",17.683104,6.239964,-1.502761929,{"v":1.14e-160,"d":"1.14E-160"},{"v":1.06e-159,"d":"1.06E-159"},"down","MEGF9","-","-","-","KOG0994-Extracellular matrix glycoprotein Laminin subunit beta[W]"]
["KIF26A",19.091639,6.735609,-1.503060664,{"v":2.13e-230,"d":"2.13E-230"},{"v":2.62e-229,"d":"2.62E-229"},"down","KIF26A","-","GO:0000166;GO:0001560;GO:0003774;GO:0003777;GO:0005524;GO:0005871;GO:0007018;GO:0008017;GO:0009968;GO:0016887;GO:0048484","-","KOG4280-Kinesin-like protein[Z]"]
["SH3GL1",105.329895,36.924633,-1.512259477,0,0,"down","SH3GL1","SH3 domain containing GRB2 like 1, endophilin A2","GO:0002102;GO:0005737;GO:0005768;GO:0005829;GO:0006897;GO:0008289;GO:0016020;GO:0016191;GO:0030054;GO:0031901;GO:0042802;GO:0042995;GO:0098793;GO:0098978","K11247-ko04144 Endocytosis","KOG1118-Lysophosphatidic acid acyltransferase endophilin/SH3GL, involved in synaptic vesicle formation[IT]"]
["ADIPOQ",481.204926,168.545792,-1.513510802,0,0,"down","ADIPOQ","adiponectin, C1Q and collagen domain containing","GO:0001934;GO:0005102;GO:0005179;GO:0005576;GO:0005581;GO:0005615;GO:0005783;GO:0006006;GO:0006635;GO:0009617;GO:0009749;GO:0009967;GO:0009986;GO:0010469;GO:0010642;GO:0010739;GO:0010745;GO:0010804;GO:0010875;GO:0010906;GO:0019395;GO:0030336;GO:0030853;GO:0031953;GO:0032270;GO:0032720;GO:0032757;GO:0032869;GO:0033034;GO:0033691;GO:0034115;GO:0034383;GO:0034612;GO:0035690;GO:0042593;GO:0042802;GO:0042803;GO:0043123;GO:0043124;GO:0043407;GO:0045599;GO:0045650;GO:0045715;GO:0045721;GO:0045776;GO:0045892;GO:0045923;GO:0046326;GO:0050728;GO:0050765;GO:0050805;GO:0051260;GO:0070208;GO:0070373;GO:0070994;GO:0071639;GO:0072659;GO:0090317;GO:0120162;GO:0120163;GO:1900121;GO:1904706;GO:1904753;GO:2000279;GO:2000478;GO:2000481;GO:2000534;GO:2000584;GO:2000590","K07296-ko04152 AMPK signaling pathway;ko04920 Adipocytokine signaling pathway;ko03320 PPAR signaling pathway;ko04211 Longevity regulating pathway - mammal;ko04930 Type II diabetes mellitus;ko04932 Non-alcoholic fatty liver disease (NAFLD)","-"]
["LOC107050031",14.609249,5.113828,-1.514406475,{"v":3.79e-10,"d":"3.79E-10"},{"v":8.35e-10,"d":"8.35E-10"},"down","LOC107050031","-","-","-","-"]
["VCPKMT",22.891722,7.999342,-1.516872753,{"v":4.66e-42,"d":"4.66E-42"},{"v":1.93e-41,"d":"1.93E-41"},"down","VCPKMT","-","GO:0005737;GO:0005829;GO:0016279;GO:0018022;GO:0018023;GO:0032780;GO:0032991;GO:0051117","-","-"]
["DFNA5",17.031233,5.946833,-1.517989417,{"v":8.27e-75,"d":"8.27E-75"},{"v":4.63e-74,"d":"4.63E-74"},"down","DFNA5","DFNA5, deafness associated tumor suppressor","GO:0005546;GO:0005829;GO:0005886;GO:0008219;GO:0008285;GO:0016020;GO:0043410;GO:0060113;GO:0070265;GO:0070269;GO:0071356;GO:0098586;GO:1901612;GO:2001244","-","-"]
["NAALADL2",10.021141,3.491892,-1.520965938,{"v":2.54e-172,"d":"2.54E-172"},{"v":2.5e-171,"d":"2.50E-171"},"down","NAALADL2","-","GO:0005654;GO:0009617;GO:0016020;GO:0016021","-","KOG2195-Transferrin receptor and related proteins containing the protease-associated (PA) domain[OPR]"]
["PCMTD1",59.009438,20.536322,-1.522767896,0,0,"down","PCMTD1","protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1","GO:0004719;GO:0006464;GO:0006479;GO:0032259;GO:0004719;GO:0005737;GO:0006464;GO:0006479;GO:0032259","-","KOG1661-Protein-L-isoaspartate(D-aspartate) O-methyltransferase[O]"]
["TYRO3",34.809715,12.106254,-1.523737477,{"v":1.14e-266,"d":"1.14E-266"},{"v":1.57e-265,"d":"1.57E-265"},"down","TYRO3","TYRO3 protein tyrosine kinase","GO:0000166;GO:0001779;GO:0004672;GO:0004713;GO:0005524;GO:0005622;GO:0006468;GO:0007218;GO:0007283;GO:0009986;GO:0016020;GO:0016021;GO:0016301;GO:0016310;GO:0016740;GO:0018108;GO:0021885;GO:0030168;GO:0032940;GO:0034122;GO:0034446;GO:0042698;GO:0043277;GO:0043491;GO:0043524;GO:0043548;GO:0045824;GO:0046777;GO:0046982;GO:0050728;GO:0051250;GO:0060068;GO:0070050;GO:0070527;GO:0000166;GO:0004672;GO:0004713;GO:0004714;GO:0005524;GO:0005886;GO:0006468;GO:0007155;GO:0016020;GO:0016021;GO:0016301;GO:0016310;GO:0016740;GO:0018108","-","KOG1095-Protein tyrosine kinase[T]"]
["ITGA11",12.532176,4.358007,-1.523896517,{"v":5.22e-90,"d":"5.22E-90"},{"v":3.27e-89,"d":"3.27E-89"},"down","ITGA11","-","GO:0005518;GO:0005925;GO:0006929;GO:0007155;GO:0007160;GO:0007229;GO:0008305;GO:0016020;GO:0016021;GO:0033627;GO:0034681;GO:0038064;GO:0038065;GO:0098639","K06587-ko04151 PI3K-Akt signaling pathway;ko04512 ECM-receptor interaction;ko04810 Regulation of actin cytoskeleton;ko04510 Focal adhesion;ko05410 Hypertrophic cardiomyopathy (HCM);ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC);ko05414 Dilated cardiomyopathy (DCM)","KOG3637-Vitronectin receptor, alpha subunit[W]"]
["PNAT3",47.53194,16.526505,-1.524115628,{"v":1.47e-143,"d":"1.47E-143"},{"v":1.27e-142,"d":"1.27E-142"},"down","PNAT3","N-acetyltransferase, pineal gland isozyme NAT-3","-","K00622-ko00232 Caffeine metabolism;ko00633 Nitrotoluene degradation;ko00983 Drug metabolism - other enzymes;ko05204 Chemical carcinogenesis","-"]
["PGD",572.025024,198.711777,-1.525400882,0,0,"down","PGD","phosphogluconate dehydrogenase","GO:0004616;GO:0006098;GO:0009051;GO:0016491;GO:0019322;GO:0019521;GO:0050661;GO:0055114;GO:0004616;GO:0006098;GO:0016491;GO:0019521;GO:0050661;GO:0055114","K00033-ko01200 Carbon metabolism;ko00030 Pentose phosphate pathway;ko00480 Glutathione metabolism","KOG2653-6-phosphogluconate dehydrogenase[G]"]
["GGT1",29.954132,10.403666,-1.525663039,{"v":1.22e-124,"d":"1.22E-124"},{"v":9.5e-124,"d":"9.50E-124"},"down","GGT1","-","GO:0006508;GO:0006751;GO:0036374","K18592-ko00590 Arachidonic acid metabolism;ko00430 Taurine and hypotaurine metabolism;ko00460 Cyanoamino acid metabolism;ko00480 Glutathione metabolism","-"]
["IPPK",45.383915,15.758293,-1.526069802,0,0,"down","IPPK","inositol-pentakisphosphate 2-kinase","GO:0000166;GO:0005524;GO:0005634;GO:0016301;GO:0016310;GO:0016740;GO:0032958;GO:0035299;GO:0052746","K10572-ko00562 Inositol phosphate metabolism;ko04070 Phosphatidylinositol signaling system","KOG4749-Inositol polyphosphate kinase[T]"]
["COMMD1",87.652832,30.415545,-1.526991849,{"v":3.59e-100,"d":"3.59E-100"},{"v":2.41e-99,"d":"2.41E-99"},"down","COMMD1","-","GO:0005507;GO:0005546;GO:0005547;GO:0005634;GO:0005654;GO:0005737;GO:0005768;GO:0005769;GO:0005829;GO:0006893;GO:0031398;GO:0031462;GO:0032088;GO:0032434;GO:0042802;GO:0042803;GO:0043325;GO:0048227;GO:0055037;GO:0055070;GO:0070300;GO:0080025;GO:1902306;GO:2000009","-","-"]
["DHCR7",23.808407,8.252069,-1.528643305,{"v":3.86e-162,"d":"3.86E-162"},{"v":3.63e-161,"d":"3.63E-161"},"down","DHCR7","7-dehydrocholesterol reductase","GO:0001568;GO:0005640;GO:0005783;GO:0005829;GO:0006695;GO:0009791;GO:0009918;GO:0016020;GO:0016021;GO:0016126;GO:0016132;GO:0016628;GO:0030154;GO:0030176;GO:0030324;GO:0035264;GO:0042127;GO:0047598;GO:0055114","K00213-ko00100 Steroid biosynthesis","KOG1435-Sterol reductase/lamin B receptor[IT]"]
["LOC422171",17.668489,6.103777,-1.533404507,{"v":8.92e-208,"d":"8.92E-208"},{"v":1.02e-206,"d":"1.02E-206"},"down","LOC422171","-","GO:0005096;GO:0007165;GO:0043547","-","-"]
["COL1A1",552.848999,190.717499,-1.535448265,0,0,"down","COL1A1","-","GO:0005201;GO:0005576;GO:0005581;GO:0046872","K06236-ko04151 PI3K-Akt signaling pathway;ko04512 ECM-receptor interaction;ko04510 Focal adhesion;ko04611 Platelet activation;ko04974 Protein digestion and absorption;ko04933 AGE-RAGE signaling pathway in diabetic complications;ko05146 Amoebiasis","KOG3546-Collagens (type XV)[W]"]
["LOC112533600",125.039642,43.106766,-1.536399317,{"v":7.55e-32,"d":"7.55E-32"},{"v":2.71e-31,"d":"2.71E-31"},"down","LOC112533600","-","-","-","-"]
["NECTIN1",35.380821,12.170693,-1.539556208,0,0,"down","NECTIN1","-","-","K06081-ko04514 Cell adhesion molecules (CAMs);ko04520 Adherens junction;ko05168 Herpes simplex infection","-"]
["CDCA7",6.620206,2.268795,-1.544949852,{"v":6.18e-40,"d":"6.18E-40"},{"v":2.49e-39,"d":"2.49E-39"},"down","CDCA7","-","GO:0005634;GO:0005654;GO:0005829;GO:0006355;GO:0042127","-","-"]
["GMFB",36.129333,12.368729,-1.546473363,{"v":1.47e-127,"d":"1.47E-127"},{"v":1.17e-126,"d":"1.17E-126"},"down","GMFB","glia maturation factor beta","GO:0003779;GO:0005622;GO:0007612;GO:0007626;GO:0034316;GO:0071933","-","KOG1736-Glia maturation factor beta[W]"]
["CHRDL1",66.824265,22.842871,-1.548628078,0,0,"down","CHRDL1","chordin like 1","GO:0001654;GO:0030514;GO:0048749;GO:0005576;GO:0007275","-","-"]
["STEAP1",11.34937,3.870919,-1.551864192,{"v":1.3e-31,"d":"1.30E-31"},{"v":4.66e-31,"d":"4.66E-31"},"down","STEAP1","-","GO:0005768;GO:0005886;GO:0016020;GO:0016021","-","-"]
["C3H1ORF198",68.440277,23.322479,-1.553124455,0,0,"down","C3H1ORF198","-","GO:0005829","-","-"]
["DSTN",901.135681,305.877533,-1.558790201,0,0,"down","DSTN","destrin, actin depolymerizing factor","GO:0003779;GO:0005622;GO:0015629;GO:0030042;GO:0030836;GO:0051014;GO:0051015;GO:0003779;GO:0005622;GO:0005737;GO:0015629;GO:0030042;GO:0030043;GO:0030836;GO:0030864;GO:0051014;GO:0051015","-","KOG1735-Actin depolymerizing factor[Z]"]
["RND2",11.180139,3.789996,-1.560669894,{"v":5.51e-14,"d":"5.51E-14"},{"v":1.38e-13,"d":"1.38E-13"},"down","RND2","Rho family GTPase 2","GO:0000166;GO:0003924;GO:0005525;GO:0005622;GO:0007264;GO:0048672","-","KOG0393-Ras-related small GTPase, Rho type[R]"]
["KIFC1",12.175081,4.126291,-1.561013897,{"v":8.6e-45,"d":"8.60E-45"},{"v":3.67e-44,"d":"3.67E-44"},"down","KIFC1","kinesin family member C1","GO:0000166;GO:0003774;GO:0003777;GO:0005524;GO:0005874;GO:0007018;GO:0008017","-","-"]
["SAPCD2",28.525919,9.664006,-1.56158011,{"v":4.18e-146,"d":"4.18E-146"},{"v":3.65e-145,"d":"3.65E-145"},"down","SAPCD2","-","-","-","-"]
["LOC112533598",103.060745,34.913685,-1.561630386,{"v":3.34e-27,"d":"3.34E-27"},{"v":1.11e-26,"d":"1.11E-26"},"down","LOC112533598","-","-","-","-"]
["IL1RL2",18.927824,6.409379,-1.562252077,{"v":8.75e-278,"d":"8.75E-278"},{"v":1.24e-276,"d":"1.24E-276"},"down","IL1RL2","-","GO:0004908;GO:0004909;GO:0007165;GO:0016020;GO:0016021;GO:0019221;GO:0070498","-","-"]
["BTBD11",14.07784,4.766912,-1.562299097,0,0,"down","BTBD11","-","GO:0060395","-","KOG4350-Uncharacterized conserved protein, contains BTB/POZ domain[R]"]
["CABLES1",13.794585,4.663525,-1.564609298,{"v":6.78e-198,"d":"6.78E-198"},{"v":7.33e-197,"d":"7.33E-197"},"down","CABLES1","-","GO:0005829;GO:0007399;GO:0051726","-","KOG4164-Cyclin ik3-1/CABLES[D]"]
["MIF",448.397888,151.561966,-1.564871724,0,0,"down","MIF","macrophage migration inhibitory factor (glycosylation-inhibiting factor)","GO:0002376;GO:0004167;GO:0005125;GO:0005576;GO:0005615;GO:0005737;GO:0006954;GO:0010469;GO:0016853;GO:0042289;GO:0045087;GO:0050178","K07253-ko00350 Tyrosine metabolism;ko00360 Phenylalanine metabolism","KOG1759-Macrophage migration inhibitory factor[V]"]
["SLC18A3",5.604542,1.894168,-1.565032188,{"v":6.78e-16,"d":"6.78E-16"},{"v":1.78e-15,"d":"1.78E-15"},"down","SLC18A3","solute carrier family 18 member A3","GO:0016020;GO:0016021;GO:0055085","-","KOG3764-Vesicular amine transporter[U]"]
["MACC1",12.417057,4.196175,-1.565176526,{"v":1.02e-127,"d":"1.02E-127"},{"v":8.1e-127,"d":"8.10E-127"},"down","MACC1","-","GO:0000977;GO:0001228;GO:0005737;GO:0005739;GO:0006366;GO:0045944","-","-"]
["LUM",124.22467,41.973232,-1.565410247,0,0,"down","LUM","lumican","GO:0007601;GO:0030199;GO:0062023;GO:0005518;GO:0005576;GO:0005583;GO:0005615;GO:0007409;GO:0007601;GO:0030199;GO:0031012;GO:0032914;GO:0045944;GO:0062023","-","KOG4194-Membrane glycoprotein LIG-1[T]"]
["S100A11",1554.452759,525.012756,-1.565982392,0,0,"down","S100A11","S100 calcium binding protein A11","GO:0001726;GO:0005509;GO:0005634;GO:0005737;GO:0042127;GO:0042803;GO:0044548;GO:0046872;GO:0048306","-","-"]
["NOD1",12.240882,4.132252,-1.56670737,{"v":3.69e-234,"d":"3.69E-234"},{"v":4.61e-233,"d":"4.61E-233"},"down","NOD1","nucleotide binding oligomerization domain containing 1","GO:0000166;GO:0002606;GO:0005524;GO:0005737;GO:0006919;GO:0016045;GO:0016323;GO:0032755;GO:0032760;GO:0032874;GO:0035556;GO:0042228;GO:0042742;GO:0042802;GO:0042803;GO:0042981;GO:0043123;GO:0043280;GO:0046330;GO:0050700;GO:0050830;GO:0051092;GO:0070374;GO:0071225;GO:1901224;GO:1904417","K08727-ko04621 NOD-like receptor signaling pathway;ko05120 Epithelial cell signaling in Helicobacter pylori infection;ko05131 Shigellosis;ko05133 Pertussis","KOG4308-LRR-containing protein[S]"]
["PRAG1",8.490072,2.864943,-1.567270353,{"v":2.29e-41,"d":"2.29E-41"},{"v":9.39e-41,"d":"9.39E-41"},"down","PRAG1","-","GO:0004672;GO:0005524;GO:0005925;GO:0006468;GO:0016477;GO:0042802","-","KOG4158-BRPK/PTEN-induced protein kinase[T]"]
["ATP9A",32.874504,11.088088,-1.567958515,0,0,"down","ATP9A","-","GO:0000166;GO:0000287;GO:0004012;GO:0005524;GO:0005768;GO:0005769;GO:0005802;GO:0005886;GO:0006890;GO:0006897;GO:0015914;GO:0016020;GO:0016021;GO:0016787;GO:0045332;GO:0048471;GO:0055037","-","KOG0210-P-type ATPase[P]"]
["TPD52",156.904465,52.920872,-1.567977669,0,0,"down","TPD52","tumor protein D52","GO:0005509;GO:0005737;GO:0005783;GO:0042802;GO:0042803;GO:0046982;GO:0048471","-","KOG4010-Coiled-coil protein TPD52[R]"]
["FOXP2",15.047552,5.074345,-1.568235287,{"v":1.56e-130,"d":"1.56E-130"},{"v":1.26e-129,"d":"1.26E-129"},"down","FOXP2","forkhead box P2","GO:0000122;GO:0000978;GO:0000981;GO:0002053;GO:0003677;GO:0003700;GO:0005634;GO:0006351;GO:0006355;GO:0007519;GO:0009653;GO:0009791;GO:0021549;GO:0021757;GO:0021758;GO:0021987;GO:0030154;GO:0030324;GO:0042297;GO:0042802;GO:0042803;GO:0043010;GO:0043565;GO:0045892;GO:0046982;GO:0048286;GO:0048745;GO:0050679;GO:0060013;GO:0060501","-","KOG4385-Predicted forkhead transcription factor[K]"]
["RGS12",36.47422,12.295012,-1.568803983,0,0,"down","RGS12","-","GO:0005634;GO:0005730;GO:0005829;GO:0007165;GO:0030695;GO:0050790","-","-"]
["HSD11B2",13.81415,4.65358,-1.56973388,{"v":2.03e-79,"d":"2.03E-79"},{"v":1.18e-78,"d":"1.18E-78"},"down","HSD11B2","-","GO:0016020;GO:0016021;GO:0016491;GO:0055114","K00071-ko00140 Steroid hormone biosynthesis;ko04960 Aldosterone-regulated sodium reabsorption","KOG1610-Corticosteroid 11-beta-dehydrogenase and related short chain-type dehydrogenases[QR]"]
["SLCO4C1",19.748825,6.650903,-1.570144684,{"v":1.2e-91,"d":"1.20E-91"},{"v":7.59e-91,"d":"7.59E-91"},"down","SLCO4C1","-","GO:0005215;GO:0005886;GO:0005887;GO:0006811;GO:0015347;GO:0016020;GO:0016021;GO:0043252;GO:0055085","-","-"]
["GRK4",24.700741,8.300117,-1.573350744,{"v":4.94e-220,"d":"4.94E-220"},{"v":5.86e-219,"d":"5.86E-219"},"down","GRK4","G protein-coupled receptor kinase 4","GO:0000166;GO:0004672;GO:0004674;GO:0004703;GO:0005524;GO:0006468;GO:0007165;GO:0016301;GO:0016310;GO:0016740;GO:0031623","K08291-ko04341 Hedgehog signaling pathway - Fly;ko04144 Endocytosis;ko04062 Chemokine signaling pathway;ko05032 Morphine addiction","KOG0986-G protein-coupled receptor kinase[T]"]
["JCHAIN",12.475347,4.187132,-1.575045639,{"v":7.41e-37,"d":"7.41E-37"},{"v":2.85e-36,"d":"2.85E-36"},"down","JCHAIN","joining chain of multimeric IgA and IgM","GO:0002250;GO:0003094;GO:0003697;GO:0005615;GO:0019731;GO:0019862;GO:0030674;GO:0031210;GO:0032461;GO:0034987;GO:0042803;GO:0042834;GO:0045087;GO:0060267;GO:0071748;GO:0071750;GO:0071751;GO:0071752;GO:0071756","-","-"]
["CNR1",10.768368,3.613192,-1.575453794,{"v":3.15e-98,"d":"3.15E-98"},{"v":2.09e-97,"d":"2.09E-97"},"down","CNR1","cannabinoid receptor 1","GO:0004930;GO:0004949;GO:0005739;GO:0005886;GO:0007165;GO:0007186;GO:0007188;GO:0007413;GO:0016020;GO:0016021;GO:0030424;GO:0030426;GO:0032592;GO:0038171;GO:0042593;GO:0042734;GO:0098793;GO:0098921;GO:0098978;GO:0098982;GO:0099056;GO:0099553","K04277-ko04015 Rap1 signaling pathway;ko04080 Neuroactive ligand-receptor interaction;ko04723 Retrograde endocannabinoid signaling","KOG4219-G protein-coupled receptor[T]"]
["CES1L2",186.633911,62.571766,-1.576627417,0,0,"down","CES1L2","-","-","K01044-ko00983 Drug metabolism - other enzymes","-"]
["ABCB5",6.50199,2.175265,-1.57969017,{"v":2.13e-54,"d":"2.13E-54"},{"v":1e-53,"d":"1.00E-53"},"down","ABCB5","-","GO:0000166;GO:0005524;GO:0016020;GO:0016021;GO:0016887;GO:0042626;GO:0055085","K05658-ko02010 ABC transporters;ko04976 Bile secretion;ko05206 MicroRNAs in cancer","-"]
["RNF128",56.008247,18.729565,-1.580321881,{"v":7.19e-226,"d":"7.19E-226"},{"v":8.7e-225,"d":"8.70E-225"},"down","RNF128","-","GO:0016020;GO:0016021","-","KOG4628-Predicted E3 ubiquitin ligase[O]"]
["SAMD11",12.623847,4.220556,-1.580646653,{"v":5.14e-59,"d":"5.14E-59"},{"v":2.53e-58,"d":"2.53E-58"},"down","SAMD11","sterile alpha motif domain containing 11","-","-","-"]
["TCF3",36.646828,12.24117,-1.581946874,0,0,"down","TCF3","transcription factor 3","GO:0000122;GO:0000790;GO:0000978;GO:0003677;GO:0003700;GO:0003713;GO:0005634;GO:0005667;GO:0005737;GO:0006351;GO:0006357;GO:0008013;GO:0008134;GO:0016055;GO:0016607;GO:0031435;GO:0033152;GO:0042803;GO:0043425;GO:0045666;GO:0045893;GO:0045944;GO:0046982;GO:0046983;GO:0051091;GO:0060070;GO:0070491;GO:0070644;GO:0070888;GO:0090575","-","KOG3910-Helix loop helix transcription factor[K]"]
["ITGA3",47.54063,15.865129,-1.58330177,0,0,"down","ITGA3","integrin subunit alpha 3","GO:0001764;GO:0002020;GO:0005886;GO:0007155;GO:0007229;GO:0007613;GO:0008305;GO:0009897;GO:0009986;GO:0016020;GO:0016021;GO:0016323;GO:0017015;GO:0030111;GO:0030324;GO:0030510;GO:0031527;GO:0034667;GO:0035024;GO:0035640;GO:0043235;GO:0043588;GO:0045202;GO:0046982;GO:0048333;GO:0060076;GO:0071438;GO:0071944;GO:0072006;GO:0097060;GO:0097062;GO:0097205;GO:1903078","K06482-ko04151 PI3K-Akt signaling pathway;ko04512 ECM-receptor interaction;ko04810 Regulation of actin cytoskeleton;ko04510 Focal adhesion;ko04640 Hematopoietic cell lineage;ko05200 Pathways in cancer;ko05222 Small cell lung cancer;ko05410 Hypertrophic cardiomyopathy (HCM);ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC);ko05414 Dilated cardiomyopathy (DCM)","KOG3637-Vitronectin receptor, alpha subunit[W]"]
["ENDOD1",66.146614,22.024103,-1.586584046,0,0,"down","ENDOD1","-","GO:0003676;GO:0016020;GO:0016021;GO:0016787;GO:0046872","-","-"]
["LOC418836",181.635635,60.42622,-1.587800671,0,0,"down","LOC418836","-","-","-","-"]
["ARHGAP10",29.67017,9.864863,-1.588642272,{"v":2.95e-146,"d":"2.95E-146"},{"v":2.58e-145,"d":"2.58E-145"},"down","ARHGAP10","-","GO:0005096;GO:0005829;GO:0007010;GO:0007165;GO:0043066;GO:0043547","-","KOG1451-Oligophrenin-1 and related Rho GTPase-activating proteins[T]"]
["CENPP",5.662888,1.882366,-1.588990829,{"v":1.88e-06,"d":"1.88E-06"},{"v":3.49e-06,"d":"3.49E-06"},"down","CENPP","centromere protein P","GO:0000775;GO:0005634;GO:0005694;GO:0016020;GO:0016021;GO:0034080","-","-"]
["KAT14",38.980816,12.956261,-1.589114855,{"v":4.99e-281,"d":"4.99E-281"},{"v":7.16e-280,"d":"7.16E-280"},"down","KAT14","lysine acetyltransferase 14","GO:0000086;GO:0004402;GO:0005634;GO:0005671;GO:0016573;GO:0043966","-","KOG2626-Histone H3 (Lys4) methyltransferase complex, subunit CPS60/ASH2/BRE2[BK]"]
["GFRA2",14.295554,4.745287,-1.59099928,{"v":1.47e-71,"d":"1.47E-71"},{"v":8.06e-71,"d":"8.06E-71"},"down","GFRA2","GDNF family receptor alpha 2","GO:0005886;GO:0016020;GO:0031225;GO:0038023;GO:0005886;GO:0007169;GO:0007399;GO:0016020;GO:0031225;GO:0033141;GO:0038023","-","-"]
["FAM3D",146.584335,48.624916,-1.591963273,{"v":1.97e-301,"d":"1.97E-301"},{"v":3.01e-300,"d":"3.01E-300"},"down","FAM3D","-","GO:0003674;GO:0005575;GO:0046676;GO:0070093","-","-"]
["HEXDCL",32.664608,10.824124,-1.593478055,{"v":1.51e-100,"d":"1.51E-100"},{"v":1.02e-99,"d":"1.02E-99"},"down","HEXDCL","-","GO:0004553;GO:0005975;GO:0015929;GO:0016020;GO:0016021","K14459-ko00513 Various types of N-glycan biosynthesis;ko00511 Other glycan degradation","-"]
["INPP5A",91.799133,30.345535,-1.596996272,0,0,"down","INPP5A","-","GO:0004445;GO:0005622;GO:0016787;GO:0042731;GO:0046855;GO:0046856;GO:0048016","K01106-ko00562 Inositol phosphate metabolism;ko04070 Phosphatidylinositol signaling system","KOG1976-Inositol polyphosphate 5-phosphatase, type I[I]"]
["FHOD3",7.229795,2.388985,-1.597556945,{"v":1.81e-130,"d":"1.81E-130"},{"v":1.46e-129,"d":"1.46E-129"},"down","FHOD3","-","GO:0007015;GO:0030017;GO:0030837;GO:0045214;GO:0051639;GO:0055003","-","KOG1925-Rac1 GTPase effector FHOS[TZ]"]
["DNM1",14.07266,4.6485,-1.59805789,{"v":1.77e-93,"d":"1.77E-93"},{"v":1.14e-92,"d":"1.14E-92"},"down","DNM1","-","GO:0000166;GO:0000266;GO:0001917;GO:0003374;GO:0003924;GO:0005525;GO:0005634;GO:0005654;GO:0006897;GO:0006898;GO:0007032;GO:0007605;GO:0008017;GO:0008344;GO:0016185;GO:0019901;GO:0030117;GO:0031966;GO:0042802;GO:0043209;GO:0046983;GO:0048488;GO:0050804;GO:0051262;GO:0051932;GO:0061025;GO:0072583;GO:0098684;GO:0098835;GO:0098978;GO:1901998","K01528-ko04072 Phospholipase D signaling pathway;ko04144 Endocytosis;ko04961 Endocrine and other factor-regulated calcium reabsorption;ko04721 Synaptic vesicle cycle;ko05100 Bacterial invasion of epithelial cells","KOG0446-Vacuolar sorting protein VPS1, dynamin, and related proteins[UR]"]
["NCK2",92.382523,30.508114,-1.598426951,0,0,"down","NCK2","NCK adaptor protein 2","GO:0001784;GO:0005070;GO:0005737;GO:0005783;GO:0006417;GO:0007015;GO:0012506;GO:0016477;GO:0030032;GO:0030838;GO:0033137;GO:0036493;GO:0042102;GO:0044877;GO:0045944;GO:0048013;GO:0097110;GO:1902237;GO:1903898;GO:1903912;GO:1990441","K19862-ko04012 ErbB signaling pathway;ko04660 T cell receptor signaling pathway;ko04360 Axon guidance;ko05130 Pathogenic Escherichia coli infection","KOG4226-Adaptor protein NCK/Dock, contains SH2 and SH3 domains[T]"]
["CYSLTR1",19.562975,6.456823,-1.599229398,{"v":1.36e-255,"d":"1.36E-255"},{"v":1.82e-254,"d":"1.82E-254"},"down","CYSLTR1","-","-","K04322-ko04020 Calcium signaling pathway;ko04080 Neuroactive ligand-receptor interaction","KOG4219-G protein-coupled receptor[T]"]
["LOC419074",53.478386,17.647551,-1.599487934,{"v":9.36e-187,"d":"9.36E-187"},{"v":9.72e-186,"d":"9.72E-186"},"down","LOC419074","-","-","K10260-ko04120 Ubiquitin mediated proteolysis","-"]
["FOXD1",5.262972,1.735778,-1.600295276,{"v":9.13e-20,"d":"9.13E-20"},{"v":2.63e-19,"d":"2.63E-19"},"down","FOXD1","forkhead box D1","GO:0000981;GO:0003677;GO:0003700;GO:0005634;GO:0006351;GO:0006355;GO:0006357;GO:0007275;GO:0009653;GO:0030154;GO:0043565","-","-"]
["ANKRD29",14.643087,4.829422,-1.600297291,{"v":1.01e-137,"d":"1.01E-137"},{"v":8.44e-137,"d":"8.44E-137"},"down","ANKRD29","-","-","-","KOG4177-Ankyrin[M]"]
["CDKN3",8.903931,2.933164,-1.601984675,{"v":5.7e-19,"d":"5.70E-19"},{"v":1.62e-18,"d":"1.62E-18"},"down","CDKN3","cyclin dependent kinase inhibitor 3","GO:0000082;GO:0004721;GO:0004722;GO:0004725;GO:0005634;GO:0005737;GO:0005829;GO:0006470;GO:0007049;GO:0007050;GO:0008138;GO:0016311;GO:0016787;GO:0016791;GO:0035335;GO:0048471","-","-"]
["EPCAM",1258.162476,413.373077,-1.605801906,0,0,"down","EPCAM","epithelial cell adhesion molecule","GO:0001657;GO:0005886;GO:0005923;GO:0008284;GO:0009986;GO:0016020;GO:0016021;GO:0016323;GO:0016324;GO:0016328;GO:0023019;GO:0044877;GO:0045944;GO:0048863;GO:2000048;GO:2000648;GO:0005886;GO:0005887;GO:0005923;GO:0016020;GO:0016021;GO:0016328;GO:0098609;GO:0098641","-","-"]
["VANGL2",20.278524,6.655172,-1.60740479,{"v":9.72e-130,"d":"9.72E-130"},{"v":7.78e-129,"d":"7.78E-129"},"down","VANGL2","-","GO:0001725;GO:0001736;GO:0001843;GO:0001947;GO:0003149;GO:0003150;GO:0003402;GO:0005886;GO:0005911;GO:0007266;GO:0007275;GO:0009952;GO:0015012;GO:0016020;GO:0016021;GO:0016323;GO:0016324;GO:0016328;GO:0022007;GO:0030111;GO:0030134;GO:0032835;GO:0032956;GO:0035019;GO:0035567;GO:0035787;GO:0036342;GO:0036514;GO:0036515;GO:0042060;GO:0043507;GO:0045176;GO:0045197;GO:0048103;GO:0048546;GO:0060028;GO:0060029;GO:0060071;GO:0060119;GO:0060122;GO:0060187;GO:0060488;GO:0060489;GO:0060490;GO:0060993;GO:0061346;GO:0071944;GO:0090102;GO:0090103;GO:0090175;GO:0090177;GO:0090179;GO:1904938;GO:1905515","K04510-ko04310 Wnt signaling pathway","KOG3814-Signaling protein van gogh/strabismus[T]"]
["DACT1",29.109371,9.506848,-1.614444667,{"v":5.11e-40,"d":"5.11E-40"},{"v":2.06e-39,"d":"2.06E-39"},"down","DACT1","dishevelled binding antagonist of beta catenin 1","GO:0000122;GO:0001085;GO:0005080;GO:0005634;GO:0005654;GO:0005737;GO:0008013;GO:0021915;GO:0030177;GO:0030178;GO:0030877;GO:0031647;GO:0032091;GO:0032092;GO:0042826;GO:0045732;GO:0046329;GO:0051018;GO:0060828;GO:0070097;GO:0090090;GO:0090263;GO:1903364;GO:1904864;GO:2000095;GO:2000134","-","-"]
["TMEM9",8.849315,2.889666,-1.614663035,{"v":1.91e-30,"d":"1.91E-30"},{"v":6.7e-30,"d":"6.70E-30"},"down","TMEM9","-","GO:0016020;GO:0016021","-","KOG4007-Uncharacterized conserved protein[S]"]
["LOC107054715",5.326066,1.738403,-1.615307737,{"v":1.44e-43,"d":"1.44E-43"},{"v":6.05e-43,"d":"6.05E-43"},"down","LOC107054715","-","-","-","-"]
["SEPHS1",34.555378,11.275284,-1.615746489,{"v":6.88e-141,"d":"6.88E-141"},{"v":5.84e-140,"d":"5.84E-140"},"down","SEPHS1","selenophosphate synthetase 1","GO:0004756;GO:0005524;GO:0016260;GO:0016310;GO:0042802","K01008-ko00450 Selenocompound metabolism","KOG3939-Selenophosphate synthetase[T]"]
["CTNNBIP1",76.14489,24.824074,-1.61700732,0,0,"down","CTNNBIP1","catenin beta interacting protein 1","GO:0000122;GO:0001658;GO:0002528;GO:0005634;GO:0005737;GO:0005829;GO:0008013;GO:0009952;GO:0016055;GO:0030178;GO:0030877;GO:0031333;GO:0032091;GO:0043392;GO:0043433;GO:0045657;GO:0045669;GO:0048662;GO:0060633;GO:0070016;GO:0072201","K04493-ko04310 Wnt signaling pathway","-"]
["ZDHHC21",19.147184,6.235135,-1.618639527,{"v":2.24e-215,"d":"2.24E-215"},{"v":2.62e-214,"d":"2.62E-214"},"down","ZDHHC21","zinc finger DHHC-type containing 21","GO:0005794;GO:0005886;GO:0016020;GO:0016021;GO:0016409;GO:0016740;GO:0016746;GO:0018230;GO:0018345;GO:0019706;GO:0048733","-","KOG1315-Predicted DHHC-type Zn-finger protein[R]"]
["TMPRSS13",17.18638,5.596184,-1.618750396,{"v":4.26e-78,"d":"4.26E-78"},{"v":2.45e-77,"d":"2.45E-77"},"down","TMPRSS13","-","GO:0004252;GO:0005044;GO:0006508;GO:0006898;GO:0008233;GO:0008236;GO:0016020;GO:0016021;GO:0016787","K09643-ko05164 Influenza A","KOG3627-Trypsin[E]"]
["NXN",95.362747,31.043419,-1.619138335,0,0,"down","NXN","-","-","-","-"]
["COLEC10",25.870487,8.420712,-1.619293084,{"v":4.22e-76,"d":"4.22E-76"},{"v":2.38e-75,"d":"2.38E-75"},"down","COLEC10","collectin subfamily member 10","GO:0005537;GO:0005576;GO:0005581;GO:0005615;GO:0005737;GO:0005794;GO:0030246;GO:0042056;GO:0050918;GO:1904888","-","-"]
["EPB41L1",55.277142,17.977098,-1.620522877,0,0,"down","EPB41L1","-","GO:0003779;GO:0005198;GO:0005856;GO:0005886;GO:0008092;GO:0030866","-","KOG3527-Erythrocyte membrane protein 4.1 and related proteins of the ERM family[R]"]
["BASP1",86.722038,28.169064,-1.622287034,{"v":2.92e-164,"d":"2.92E-164"},{"v":2.78e-163,"d":"2.78E-163"},"down","BASP1","brain abundant membrane attached signal protein 1","GO:0005634;GO:0005737;GO:0005856;GO:0007275;GO:0030426;GO:0030863;GO:0031234;GO:0045892","-","-"]
["PRKCH",9.391157,3.046712,-1.624049779,{"v":4.29e-120,"d":"4.29E-120"},{"v":3.25e-119,"d":"3.25E-119"},"down","PRKCH","-","GO:0000166;GO:0004672;GO:0004674;GO:0004697;GO:0005524;GO:0005622;GO:0005737;GO:0005829;GO:0005886;GO:0005911;GO:0006468;GO:0010744;GO:0016301;GO:0016310;GO:0016740;GO:0017160;GO:0018105;GO:0019899;GO:0034351;GO:0035556;GO:0045618;GO:0046872;GO:0050861;GO:0051092;GO:0060252;GO:2000810","K18051-ko04530 Tight junction;ko04270 Vascular smooth muscle contraction;ko04750 Inflammatory mediator regulation of TRP channels","-"]
["CAPN5",42.334415,13.732341,-1.624253366,0,0,"down","CAPN5","-","GO:0004198;GO:0005622;GO:0006508;GO:0008233;GO:0008234;GO:0009986;GO:0016787","-","KOG0045-Cytosolic Ca2+-dependent cysteine protease (calpain), large subunit (EF-Hand protein superfamily)[OT]"]
["LOC107057197",7.397094,2.394669,-1.627132354,{"v":2.51e-09,"d":"2.51E-09"},{"v":5.35e-09,"d":"5.35E-09"},"down","LOC107057197","-","-","-","-"]
["FOXC1",27.476814,8.87297,-1.630725734,{"v":1.04e-94,"d":"1.04E-94"},{"v":6.74e-94,"d":"6.74E-94"},"down","FOXC1","forkhead box C1","-","-","-"]
["TLR3",16.293486,5.253379,-1.632977727,{"v":1.73e-135,"d":"1.73E-135"},{"v":1.43e-134,"d":"1.43E-134"},"down","TLR3","toll like receptor 3","GO:0001819;GO:0002376;GO:0002730;GO:0002756;GO:0003725;GO:0004888;GO:0005622;GO:0005737;GO:0006952;GO:0007165;GO:0007252;GO:0009615;GO:0010008;GO:0010628;GO:0016020;GO:0016021;GO:0032481;GO:0032722;GO:0032728;GO:0032735;GO:0032755;GO:0032757;GO:0032760;GO:0034123;GO:0034138;GO:0034346;GO:0042802;GO:0043123;GO:0043330;GO:0045078;GO:0045080;GO:0045087;GO:0045356;GO:0045359;GO:0045766;GO:0045944;GO:0046330;GO:0050729;GO:0051092;GO:0051607;GO:0071260;GO:0097191;GO:0097527;GO:1901224","K05401-ko04620 Toll-like receptor signaling pathway;ko05164 Influenza A;ko05161 Hepatitis B;ko05160 Hepatitis C;ko05168 Herpes simplex infection","KOG4194-Membrane glycoprotein LIG-1[T]"]
["SNX14",50.551327,16.283497,-1.634338402,{"v":3.74e-73,"d":"3.74E-73"},{"v":2.07e-72,"d":"2.07E-72"},"down","SNX14","sorting nexin 14","GO:0005764;GO:0005770;GO:0016020;GO:0016021;GO:0035091;GO:0080025;GO:0097352","-","-"]
["APC",6.996317,2.239352,-1.643514338,{"v":4.1e-179,"d":"4.10E-179"},{"v":4.14e-178,"d":"4.14E-178"},"down","APC","-","GO:0000281;GO:0000776;GO:0005634;GO:0005737;GO:0005813;GO:0005874;GO:0005886;GO:0005913;GO:0005923;GO:0006974;GO:0007026;GO:0007050;GO:0007094;GO:0008013;GO:0008017;GO:0008285;GO:0008286;GO:0010942;GO:0016055;GO:0016328;GO:0016342;GO:0016477;GO:0019887;GO:0019901;GO:0030027;GO:0030178;GO:0030335;GO:0030877;GO:0031274;GO:0031625;GO:0032587;GO:0032886;GO:0042802;GO:0043065;GO:0045295;GO:0045732;GO:0045736;GO:0048471;GO:0051010;GO:0051260;GO:0051988;GO:0065003;GO:0070840;GO:0090090;GO:1904781","K02085-ko04310 Wnt signaling pathway;ko04390 Hippo signaling pathway;ko04810 Regulation of actin cytoskeleton;ko04550 Signaling pathways regulating pluripotency of stem cells;ko05200 Pathways in cancer;ko05206 MicroRNAs in cancer;ko05210 Colorectal cancer;ko05217 Basal cell carcinoma;ko05213 Endometrial cancer;ko05224 Breast cancer;ko05166 HTLV-I infection","KOG2122-Beta-catenin-binding protein APC, contains ARM repeats[TZ]"]
["LOC107051537",142.776779,45.669395,-1.644461778,0,0,"down","LOC107051537","-","GO:0003677;GO:0003707;GO:0005634;GO:0006351;GO:0006355;GO:0030522;GO:0043401;GO:0048384","-","-"]
["MT3",163.637817,52.302948,-1.645542026,{"v":5.19e-56,"d":"5.19E-56"},{"v":2.49e-55,"d":"2.49E-55"},"down","MT3","metallothionein 3","-","-","-"]
["AQP5",204.415756,65.323479,-1.645832868,0,0,"down","AQP5","-","GO:0005737;GO:0005783;GO:0005886;GO:0005902;GO:0006833;GO:0009925;GO:0015250;GO:0015267;GO:0015670;GO:0016020;GO:0016021;GO:0016324;GO:0030157;GO:0042802;GO:0046541;GO:0048593;GO:0055085","-","KOG0223-Aquaporin (major intrinsic protein family)[G]"]
["FBXL15",24.584982,7.851607,-1.646717431,{"v":2.69e-151,"d":"2.69E-151"},{"v":2.41e-150,"d":"2.41E-150"},"down","FBXL15","-","GO:0000086;GO:0004842;GO:0005737;GO:0016567;GO:0019005;GO:0030513;GO:0031146","-","KOG4341-F-box protein containing LRR[R]"]
["CYP51A1",72.295113,23.081512,-1.647160394,{"v":2.51e-292,"d":"2.51E-292"},{"v":3.74e-291,"d":"3.74E-291"},"down","CYP51A1","cytochrome P450 family 51 subfamily A member 1","GO:0004497;GO:0005506;GO:0005783;GO:0016491;GO:0016705;GO:0020037;GO:0046872;GO:0055114","K05917-ko00100 Steroid biosynthesis","KOG0684-Cytochrome P450[Q]"]
["SLC7AL",16.918936,5.392191,-1.649695338,{"v":1.73e-144,"d":"1.73E-144"},{"v":1.5e-143,"d":"1.50E-143"},"down","SLC7AL","-","GO:0016020;GO:0016021;GO:0022857;GO:0055085","-","-"]
["FLVCR2",12.497704,3.980065,-1.650799179,{"v":1.16e-73,"d":"1.16E-73"},{"v":6.44e-73,"d":"6.44E-73"},"down","FLVCR2","-","GO:0015232;GO:0015886;GO:0016020;GO:0016021;GO:0020037;GO:0055085","-","KOG2563-Permease of the major facilitator superfamily[R]"]
["ARHGEF5",11.99891,3.820736,-1.650980874,{"v":1.82e-172,"d":"1.82E-172"},{"v":1.79e-171,"d":"1.79E-171"},"down","ARHGEF5","-","GO:0005085;GO:0005089;GO:0005622;GO:0035023;GO:0035556","-","-"]
["BST1",67.587326,21.510508,-1.651711141,{"v":8.13e-196,"d":"8.13E-196"},{"v":8.74e-195,"d":"8.74E-195"},"down","BST1","bone marrow stromal cell antigen 1","GO:0001931;GO:0001952;GO:0003953;GO:0005886;GO:0008152;GO:0008284;GO:0008305;GO:0016787;GO:0016798;GO:0016849;GO:0019898;GO:0030890;GO:0032956;GO:0050727;GO:0050730;GO:0050848;GO:0061810;GO:0061811;GO:0061812;GO:0090022","K18152-ko00760 Nicotinate and nicotinamide metabolism;ko04970 Salivary secretion;ko04972 Pancreatic secretion","-"]
["CERCAM",72.095947,22.936415,-1.652278245,0,0,"down","CERCAM","-","GO:0007155;GO:0016020;GO:0016021","-","KOG4179-Lysyl hydrolase/glycosyltransferase family 25[O]"]
["CAP2",99.286774,31.577868,-1.652687779,0,0,"down","CAP2","-","GO:0000902;GO:0003779;GO:0007010;GO:0007163;GO:0007165;GO:0008154;GO:0008179;GO:0014069;GO:0030864;GO:0042802;GO:0045761","-","KOG2675-Adenylate cyclase-associated protein (CAP/Srv2p)[ZT]"]
["MMP23B",23.776455,7.560518,-1.652976642,{"v":4.57e-144,"d":"4.57E-144"},{"v":3.95e-143,"d":"3.95E-143"},"down","MMP23B","-","GO:0000003;GO:0004222;GO:0006508;GO:0008233;GO:0008237;GO:0008270;GO:0016020;GO:0016021;GO:0016787;GO:0031012;GO:0046872","-","KOG1565-Gelatinase A and related matrix metalloproteases[OW]"]
["DNAJB5",47.703651,15.154771,-1.654327635,0,0,"down","DNAJB5","-","GO:0000122;GO:0005634;GO:0005829;GO:0006457;GO:0006986;GO:0051082;GO:0051087","-","KOG0714-Molecular chaperone (DnaJ superfamily)[O]"]
["BAIAP2",55.564171,17.647961,-1.654653393,0,0,"down","BAIAP2","-","GO:0005829;GO:0005886;GO:0007009;GO:0008093;GO:0008360;GO:0009617;GO:0015629;GO:0016358;GO:0032956;GO:0042802;GO:0043005;GO:0048167;GO:0050804;GO:0051017;GO:0051764;GO:0070064;GO:0098685;GO:0099564","K05627-ko04810 Regulation of actin cytoskeleton;ko04520 Adherens junction","-"]
["CLMP",40.424995,12.830652,-1.655653111,{"v":9.69e-289,"d":"9.69E-289"},{"v":1.42e-287,"d":"1.42E-287"},"down","CLMP","-","GO:0005881;GO:0005923;GO:0016020;GO:0016021;GO:0048565","-","KOG3513-Neural cell adhesion molecule L1[T]"]
["TWIST2",24.196768,7.670782,-1.657368791,{"v":2.61e-56,"d":"2.61E-56"},{"v":1.26e-55,"d":"1.26E-55"},"down","TWIST2","twist family bHLH transcription factor 2","-","-","KOG4447-Transcription factor TWIST[K]"]
["GK5",42.366436,13.409393,-1.659677837,{"v":2.01e-187,"d":"2.01E-187"},{"v":2.09e-186,"d":"2.09E-186"},"down","GK5","glycerol kinase 5 (putative)","GO:0005975;GO:0016301;GO:0016310;GO:0016740;GO:0016773;GO:0000166;GO:0004370;GO:0005524;GO:0005739;GO:0005975;GO:0006071;GO:0006641;GO:0016301;GO:0016310;GO:0016740;GO:0016773;GO:0019563;GO:0046167","-","KOG2517-Ribulose kinase and related carbohydrate kinases[G]"]
["TET3",10.075491,3.181913,-1.662883851,{"v":6.28e-100,"d":"6.28E-100"},{"v":4.21e-99,"d":"4.21E-99"},"down","TET3","-","-","-","-"]
["SH3D19",108.168221,34.114372,-1.664825145,0,0,"down","SH3D19","-","GO:0005654;GO:0005829;GO:0005886;GO:0007010;GO:0022604;GO:0051044","-","KOG1029-Endocytic adaptor protein intersectin[TU]"]
["MEIS2",79.08902,24.93206,-1.665475328,0,0,"down","MEIS2","Meis homeobox 2","GO:0003677;GO:0005634;GO:0006355","-","-"]
["TGM4",79.731148,25.098286,-1.667554598,0,0,"down","TGM4","transglutaminase 4","GO:0003810;GO:0005737;GO:0005794;GO:0018149;GO:0031012;GO:0046872","-","-"]
["PAK6",15.449594,4.857313,-1.669338566,{"v":3.21e-179,"d":"3.21E-179"},{"v":3.25e-178,"d":"3.25E-178"},"down","PAK6","-","GO:0000166;GO:0004672;GO:0004674;GO:0005524;GO:0006468;GO:0007612;GO:0007613;GO:0007626;GO:0016301;GO:0016310;GO:0016740","K05735-ko04014 Ras signaling pathway;ko04012 ErbB signaling pathway;ko04810 Regulation of actin cytoskeleton;ko04510 Focal adhesion;ko04660 T cell receptor signaling pathway;ko04360 Axon guidance;ko05211 Renal cell carcinoma","-"]
["DLK2",23.558264,7.401934,-1.670259055,{"v":3.27e-120,"d":"3.27E-120"},{"v":2.48e-119,"d":"2.48E-119"},"down","DLK2","-","GO:0005509;GO:0016020;GO:0016021;GO:0042803;GO:0045598;GO:0045746","-","KOG1217-Fibrillins and related proteins containing Ca2+-binding EGF-like domains[T]"]
["NAT",6.426097,2.019034,-1.670277553,{"v":2.2e-16,"d":"2.20E-16"},{"v":5.87e-16,"d":"5.87E-16"},"down","NAT","N-acetyltransferase, liver isozyme","GO:0008152;GO:0016407;GO:0016740;GO:0016746","K00622-ko00232 Caffeine metabolism;ko00633 Nitrotoluene degradation;ko00983 Drug metabolism - other enzymes;ko05204 Chemical carcinogenesis","-"]
["TNIP2",27.225742,8.548777,-1.671181422,{"v":1.29e-126,"d":"1.29E-126"},{"v":1.02e-125,"d":"1.02E-125"},"down","TNIP2","TNFAIP3 interacting protein 2","GO:0005634;GO:0005654;GO:0005737;GO:0005829;GO:0007249;GO:0019901;GO:0023035;GO:0031593;GO:0034134;GO:0034138;GO:0034162;GO:0043032;GO:0043123;GO:0045944;GO:0050821;GO:0050871;GO:0070498;GO:0070530;GO:0071222;GO:2000352","-","-"]
["NGEF",46.859749,14.711992,-1.671356626,0,0,"down","NGEF","neuronal guanine nucleotide exchange factor","GO:0005089;GO:0035023;GO:0005089;GO:0035023","-","KOG3523-Putative guanine nucleotide exchange factor TIM[T]"]
["RAD51",9.783739,3.065927,-1.674062571,{"v":3.76e-24,"d":"3.76E-24"},{"v":1.18e-23,"d":"1.18E-23"},"down","RAD51","RAD51 recombinase","GO:0003677;GO:0005524;GO:0006281;GO:0008094","K04482-ko03440 Homologous recombination;ko03460 Fanconi anemia pathway;ko05200 Pathways in cancer;ko05212 Pancreatic cancer","KOG1433-DNA repair protein RAD51/RHP55[L]"]
["KLC1",32.425323,10.154065,-1.675063545,{"v":2.04e-167,"d":"2.04E-167"},{"v":1.96e-166,"d":"1.96E-166"},"down","KLC1","-","GO:0003777;GO:0005871","K10407-ko05132 Salmonella infection","-"]
["DYL1",600.433716,187.873795,-1.67624114,0,0,"down","DYL1","dynein light chain 1 cytoplasmic","GO:0003774;GO:0005737;GO:0005856;GO:0005874;GO:0005875;GO:0007017;GO:0030286","-","KOG3430-Dynein light chain type 1[Z]"]
["ANKDD1B",7.516185,2.349337,-1.677746902,{"v":4.37e-44,"d":"4.37E-44"},{"v":1.85e-43,"d":"1.85E-43"},"down","ANKDD1B","-","GO:0007165","-","KOG4177-Ankyrin[M]"]
["SLC7A11",6.375631,1.99218,-1.678220128,{"v":1.42e-59,"d":"1.42E-59"},{"v":7.05e-59,"d":"7.05E-59"},"down","SLC7A11","-","GO:0005887;GO:0006865;GO:0009636;GO:0009986;GO:0015327;GO:0015813;GO:0016020;GO:0016021;GO:0022857;GO:0055085;GO:0070527","-","KOG1287-Amino acid transporters[E]"]
["SLC38A4",35.43259,11.070102,-1.67840841,{"v":1.65e-187,"d":"1.65E-187"},{"v":1.72e-186,"d":"1.72E-186"},"down","SLC38A4","solute carrier family 38 member 4","GO:0003333;GO:0005887;GO:0015171;GO:0016020;GO:0016021","-","KOG1305-Amino acid transporter protein[E]"]
["KCNA2",11.478741,3.585962,-1.678532309,{"v":6.33e-49,"d":"6.33E-49"},{"v":2.82e-48,"d":"2.82E-48"},"down","KCNA2","potassium voltage-gated channel subfamily A member 2","GO:0005216;GO:0005244;GO:0005249;GO:0005267;GO:0005887;GO:0006811;GO:0006813;GO:0008076;GO:0014059;GO:0016020;GO:0016021;GO:0021633;GO:0030424;GO:0030425;GO:0032809;GO:0034765;GO:0043204;GO:0043679;GO:0044224;GO:0045188;GO:0051260;GO:0055085;GO:0071805","-","KOG1545-Voltage-gated shaker-like K+ channel KCNA[P]"]
["KDF1",26.743235,8.350115,-1.67930602,{"v":2.67e-189,"d":"2.67E-189"},{"v":2.8e-188,"d":"2.80E-188"},"down","KDF1","-","GO:0003334;GO:0005654;GO:0005737;GO:0005938;GO:0010482;GO:0010839;GO:0016331;GO:0030054;GO:0031252;GO:0045606;GO:0048589;GO:0060887;GO:0061436;GO:0072686;GO:2000647","-","-"]
["LOC112529921",5.447884,1.700396,-1.679825215,{"v":1.05e-14,"d":"1.05E-14"},{"v":2.69e-14,"d":"2.69E-14"},"down","LOC112529921","-","-","-","-"]
["C3orf70",28.101088,8.766598,-1.68053699,{"v":5.61e-202,"d":"5.61E-202"},{"v":6.25e-201,"d":"6.25E-201"},"down","C3orf70","-","-","-","-"]
["LOC107056280",41.796837,13.032997,-1.681224893,{"v":4.66e-198,"d":"4.66E-198"},{"v":5.04e-197,"d":"5.04E-197"},"down","LOC107056280","-","-","-","-"]
["PLCD3",41.276348,12.870545,-1.681242186,{"v":1.62e-228,"d":"1.62E-228"},{"v":1.98e-227,"d":"1.98E-227"},"down","PLCD3","-","GO:0001525;GO:0004435;GO:0005509;GO:0005622;GO:0006629;GO:0007165;GO:0008081;GO:0016042;GO:0016787;GO:0035556;GO:0042127","K05857-ko00562 Inositol phosphate metabolism;ko04020 Calcium signaling pathway;ko04070 Phosphatidylinositol signaling system;ko04919 Thyroid hormone signaling pathway;ko04933 AGE-RAGE signaling pathway in diabetic complications","KOG0169-Phosphoinositide-specific phospholipase C[T]"]
["ATP11C",92.87043,28.931614,-1.682572506,0,0,"down","ATP11C","-","GO:0000166;GO:0000287;GO:0002329;GO:0004012;GO:0005524;GO:0005783;GO:0005886;GO:0015914;GO:0016020;GO:0016021;GO:0016787;GO:0045332;GO:0045579;GO:0055037","-","KOG0206-P-type ATPase[R]"]
["PLK2",54.107872,16.844896,-1.683526982,{"v":1.05e-264,"d":"1.05E-264"},{"v":1.43e-263,"d":"1.43E-263"},"down","PLK2","-","GO:0000082;GO:0000166;GO:0000278;GO:0000785;GO:0004672;GO:0004674;GO:0005524;GO:0005737;GO:0005813;GO:0005814;GO:0006468;GO:0007052;GO:0007093;GO:0007613;GO:0010508;GO:0016301;GO:0016310;GO:0016525;GO:0016740;GO:0018105;GO:0043008;GO:0043066;GO:0045732;GO:0046599;GO:0048167;GO:0071866;GO:0090050;GO:2000773","K08861-ko04068 FoxO signaling pathway","KOG0575-Polo-like serine/threonine protein kinase[D]"]
["RPIA",233.504654,72.691383,-1.683595046,0,0,"down","RPIA","ribose 5-phosphate isomerase A","GO:0004751;GO:0005829;GO:0006014;GO:0009052;GO:0042802;GO:0043231","K01807-ko01200 Carbon metabolism;ko01230 Biosynthesis of amino acids;ko00030 Pentose phosphate pathway;ko00710 Carbon fixation in photosynthetic organisms","KOG3075-Ribose 5-phosphate isomerase[G]"]
["NAGA",59.783234,18.607107,-1.683887177,{"v":1.75e-267,"d":"1.75E-267"},{"v":2.42e-266,"d":"2.42E-266"},"down","NAGA","alpha-N-acetylgalactosaminidase","GO:0003824;GO:0004553;GO:0004557;GO:0005737;GO:0005764;GO:0005975;GO:0008152;GO:0008456;GO:0009311;GO:0016052;GO:0016139;GO:0016787;GO:0016798;GO:0019377;GO:0042803;GO:0046477","K01204-ko00603 Glycosphingolipid biosynthesis - globo series;ko04142 Lysosome","KOG2366-Alpha-D-galactosidase (melibiase)[G]"]
["LOC423277",6.815314,2.120994,-1.684039588,{"v":1.13e-18,"d":"1.13E-18"},{"v":3.18e-18,"d":"3.18E-18"},"down","LOC423277","-","GO:0030246","-","-"]
["ITGA1",35.265427,10.940977,-1.688512936,{"v":3.06e-252,"d":"3.06E-252"},{"v":4.05e-251,"d":"4.05E-251"},"down","ITGA1","integrin subunit alpha 1","GO:0005925;GO:0007155;GO:0007160;GO:0007229;GO:0008285;GO:0008305;GO:0009897;GO:0009986;GO:0016020;GO:0016021;GO:0019903;GO:0030593;GO:0032516;GO:0034665;GO:0042059;GO:0045123;GO:0045178;GO:0098639","K06480-ko04151 PI3K-Akt signaling pathway;ko04512 ECM-receptor interaction;ko04810 Regulation of actin cytoskeleton;ko04510 Focal adhesion;ko04640 Hematopoietic cell lineage;ko05410 Hypertrophic cardiomyopathy (HCM);ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC);ko05414 Dilated cardiomyopathy (DCM)","[KOG3637-Vitronectin receptor, alpha subunit[W], KOG2869-Meiotic cell division protein Pelota/DOM34[J]]"]
["NOX1",5.446912,1.688882,-1.689370027,{"v":7.72e-39,"d":"7.72E-39"},{"v":3.06e-38,"d":"3.06E-38"},"down","NOX1","NADPH oxidase 1","GO:0001525;GO:0003081;GO:0005737;GO:0005768;GO:0005769;GO:0008284;GO:0010575;GO:0016020;GO:0016021;GO:0016175;GO:0016477;GO:0016491;GO:0030198;GO:0042554;GO:0042743;GO:0043020;GO:0043410;GO:0045726;GO:0046330;GO:0048365;GO:0051454;GO:0055114;GO:0071438;GO:0071455;GO:0072592;GO:1902177;GO:1990451","K08008-ko04066 HIF-1 signaling pathway;ko04145 Phagosome;ko04670 Leukocyte transendothelial migration;ko04380 Osteoclast differentiation;ko04933 AGE-RAGE signaling pathway in diabetic complications","KOG0039-Ferric reductase, NADH/NADPH oxidase and related proteins[PQ]"]
["CNN2",49.623989,15.376629,-1.690298453,{"v":5.33e-134,"d":"5.33E-134"},{"v":4.38e-133,"d":"4.38E-133"},"down","CNN2","calponin 2","GO:0003779;GO:0005516;GO:0005856;GO:0007010;GO:0031032;GO:0003779;GO:0005516;GO:0005856;GO:0007010;GO:0010628;GO:0030097;GO:0030336;GO:0031032;GO:0042060;GO:0042127;GO:0050765","-","KOG2046-Calponin[Z]"]
["KLF4",143.733627,44.301365,-1.697974569,0,0,"down","KLF4","-","GO:0000122;GO:0000790;GO:0000978;GO:0000987;GO:0001010;GO:0001085;GO:0001190;GO:0003676;GO:0003700;GO:0005634;GO:0005654;GO:0005719;GO:0005737;GO:0006351;GO:0006357;GO:0006366;GO:0008013;GO:0008134;GO:0008285;GO:0009913;GO:0010033;GO:0010628;GO:0010629;GO:0016525;GO:0019827;GO:0030154;GO:0030336;GO:0031077;GO:0032088;GO:0032270;GO:0032526;GO:0034115;GO:0035166;GO:0042127;GO:0043154;GO:0043433;GO:0043565;GO:0044212;GO:0044798;GO:0045415;GO:0045429;GO:0045444;GO:0045595;GO:0045892;GO:0045893;GO:0045944;GO:0046985;GO:0048679;GO:0048730;GO:0051247;GO:0051973;GO:0060070;GO:0060761;GO:0061614;GO:0071363;GO:0071499;GO:0090051;GO:1903672;GO:1904798;GO:1904998;GO:1990830;GO:1990841;GO:2000134;GO:2000342","-","-"]
["LOC422150",30.942528,9.524305,-1.699905343,{"v":7.5e-107,"d":"7.50E-107"},{"v":5.24e-106,"d":"5.24E-106"},"down","LOC422150","-","-","-","-"]
["FAM3B",30.473471,9.374363,-1.70076127,{"v":1.16e-135,"d":"1.16E-135"},{"v":9.66e-135,"d":"9.66E-135"},"down","FAM3B","-","GO:0030073;GO:0042593","-","-"]
["ZNF512B",32.402382,9.950201,-1.7033023,{"v":5.21e-185,"d":"5.21E-185"},{"v":5.37e-184,"d":"5.37E-184"},"down","ZNF512B","zinc finger protein 512B","GO:0003676","-","-"]
["ELOVL1",172.070572,52.742779,-1.705954891,0,0,"down","ELOVL1","ELOVL fatty acid elongase 1","GO:0005783;GO:0005789;GO:0006629;GO:0006631;GO:0006633;GO:0006636;GO:0009922;GO:0016020;GO:0016021;GO:0016740;GO:0019367;GO:0030148;GO:0030176;GO:0034625;GO:0034626;GO:0035338;GO:0042761;GO:0102336;GO:0102337;GO:0102338;GO:0102756","K10247-ko00062 Fatty acid elongation","KOG3071-Fatty acyl-CoA elongase/Polyunsaturated fatty acid specific elongation enzyme[I]"]
["RDH12",16.131929,4.93846,-1.707785832,{"v":2.11e-67,"d":"2.11E-67"},{"v":1.12e-66,"d":"1.12E-66"},"down","RDH12","-","GO:0016491;GO:0055114","K11153-ko00830 Retinol metabolism","-"]
["TMEM140",106.895309,32.676361,-1.709879311,0,0,"down","TMEM140","-","-","-","-"]
["GJB1",23.844788,7.26624,-1.714393033,{"v":1.16e-45,"d":"1.16E-45"},{"v":5e-45,"d":"5.00E-45"},"down","GJB1","gap junction protein beta 1","GO:0005737;GO:0005886;GO:0005921;GO:0005922;GO:0007154;GO:0016020;GO:0016021;GO:0030054;GO:0042803","-","-"]
["SERPIND1",9.055037,2.755306,-1.716507985,{"v":1.05e-66,"d":"1.05E-66"},{"v":5.51e-66,"d":"5.51E-66"},"down","SERPIND1","-","GO:0004867;GO:0005615;GO:0007596;GO:0010951","-","KOG2392-Serpin[V]"]
["FAM129B",199.121262,60.513638,-1.718315054,0,0,"down","FAM129B","-","GO:0003713;GO:0005634;GO:0005654;GO:0005737;GO:0005829;GO:0005886;GO:0005912;GO:0008285;GO:0032274;GO:0043066;GO:0045892;GO:0045893;GO:2000279;GO:2000679","-","-"]
["RLN3",7.294823,2.213019,-1.720857136,{"v":5.86e-13,"d":"5.86E-13"},{"v":1.42e-12,"d":"1.42E-12"},"down","RLN3","relaxin 3","-","-","-"]
["GJA1",59.33474,17.997959,-1.721043726,{"v":7.33e-175,"d":"7.33E-175"},{"v":7.29e-174,"d":"7.29E-174"},"down","GJA1","gap junction protein alpha 1","GO:0001649;GO:0001764;GO:0001947;GO:0002070;GO:0002088;GO:0003294;GO:0005102;GO:0005243;GO:0005654;GO:0005737;GO:0005739;GO:0005794;GO:0005829;GO:0005882;GO:0005886;GO:0005911;GO:0005916;GO:0005921;GO:0005922;GO:0007154;GO:0007165;GO:0007267;GO:0007507;GO:0007512;GO:0008016;GO:0010628;GO:0010629;GO:0010643;GO:0010644;GO:0014704;GO:0015075;GO:0016020;GO:0016021;GO:0016324;GO:0016328;GO:0022857;GO:0030054;GO:0030308;GO:0030500;GO:0034220;GO:0035050;GO:0042733;GO:0043231;GO:0043292;GO:0043403;GO:0045216;GO:0045669;GO:0045844;GO:0046850;GO:0048487;GO:0048514;GO:0055085;GO:0060307;GO:0060371;GO:0060373;GO:0061337;GO:0071467;GO:0097110;GO:0120162;GO:1903763;GO:1990782","K07372-ko04540 Gap junction;ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)","-"]
["PLEKHO1",21.881346,6.63229,-1.72212249,{"v":1.01e-233,"d":"1.01E-233"},{"v":1.26e-232,"d":"1.26E-232"},"down","PLEKHO1","pleckstrin homology domain containing O1","GO:0007520;GO:0008360;GO:0032587;GO:0036195;GO:0051451;GO:0072673;GO:0005634;GO:0005737;GO:0016020","-","-"]
["CCNB2",23.373661,7.077152,-1.72364291,{"v":7.92e-65,"d":"7.92E-65"},{"v":4.08e-64,"d":"4.08E-64"},"down","CCNB2","cyclin B2","GO:0005634;GO:0005813;GO:0005829;GO:0007049;GO:0015630;GO:0016020;GO:0040008;GO:0043029;GO:0048538;GO:0051301;GO:0060317;GO:0005634","-","KOG0653-Cyclin B and related kinase-activating proteins[D]"]
["SERINC2",45.473537,13.757957,-1.724760972,{"v":2.97e-157,"d":"2.97E-157"},{"v":2.72e-156,"d":"2.72E-156"},"down","SERINC2","serine incorporator 2","GO:0006658;GO:0006665;GO:0016020;GO:0016021;GO:0006658;GO:0006665;GO:0015194;GO:0015825;GO:0016020;GO:0016021","-","KOG2592-Tumor differentially expressed (TDE) protein[S]"]
["UBASH3B",23.128672,6.995354,-1.72521346,{"v":4.73e-291,"d":"4.73E-291"},{"v":6.99e-290,"d":"6.99E-290"},"down","UBASH3B","-","GO:0004725;GO:0006469;GO:0009968;GO:0030168;GO:0035335;GO:0038063;GO:0038065;GO:0042802;GO:0043393;GO:0045670;GO:0045671;GO:0045779;GO:0051219;GO:0051279;GO:0070527;GO:0090331","-","KOG3734-Predicted phosphoglycerate mutase[G]"]
["ATP8B4",52.895714,15.983681,-1.726551134,0,0,"down","ATP8B4","-","GO:0000166;GO:0000287;GO:0001669;GO:0004012;GO:0005524;GO:0005548;GO:0005794;GO:0005886;GO:0007030;GO:0015914;GO:0016020;GO:0016021;GO:0016787;GO:0045332","-","-"]
["COL4A5",176.283569,53.217495,-1.727925503,0,0,"down","COL4A5","-","GO:0005201;GO:0005581;GO:0005587;GO:0005604;GO:0007528;GO:0031594;GO:0038063","K06237-ko04151 PI3K-Akt signaling pathway;ko04512 ECM-receptor interaction;ko04510 Focal adhesion;ko04974 Protein digestion and absorption;ko05200 Pathways in cancer;ko05222 Small cell lung cancer;ko04933 AGE-RAGE signaling pathway in diabetic complications;ko05146 Amoebiasis","-"]
["PTPRVP",33.710251,10.170012,-1.728865988,0,0,"down","PTPRVP","-","-","-","-"]
["IBTK",79.585236,23.992414,-1.729922497,0,0,"down","IBTK","-","GO:0001933;GO:0005654;GO:0005737;GO:0019901;GO:0030292;GO:0051209;GO:0061099","-","KOG0783-Uncharacterized conserved protein, contains ankyrin and BTB/POZ domains[S]"]
["LOC112533526",5.390423,1.623764,-1.731056525,0.015716049,0.021500513,"down","LOC112533526","-","-","-","-"]
["TRIM23",8.141936,2.44627,-1.734788235,{"v":3.11e-87,"d":"3.11E-87"},{"v":1.91e-86,"d":"1.91E-86"},"down","TRIM23","-","GO:0000139;GO:0000166;GO:0003676;GO:0003924;GO:0004842;GO:0005525;GO:0005622;GO:0005634;GO:0005737;GO:0005765;GO:0008270;GO:0016567;GO:0019003;GO:0042802;GO:0046872","-","KOG0070-GTP-binding ADP-ribosylation factor Arf1[U]"]
["TK1",9.535994,2.863219,-1.735745306,{"v":1.92e-14,"d":"1.92E-14"},{"v":4.87e-14,"d":"4.87E-14"},"down","TK1","thymidine kinase 1","GO:0000166;GO:0004797;GO:0005524;GO:0005737;GO:0006259;GO:0008270;GO:0009157;GO:0016301;GO:0016310;GO:0016740;GO:0042802;GO:0046104;GO:0046872;GO:0051289;GO:0071897","K00857-ko00240 Pyrimidine metabolism;ko00983 Drug metabolism - other enzymes","KOG3125-Thymidine kinase[F]"]
["CPEB2",16.412313,4.926724,-1.736078016,0,0,"down","CPEB2","-","GO:0000900;GO:0003676;GO:0003723;GO:0003730;GO:0005634;GO:0005737;GO:0006412;GO:0006417;GO:0008135;GO:0032869;GO:0043005;GO:0043022;GO:0045182;GO:0045202;GO:0071456;GO:1990124;GO:2000766","K02602-ko04114 Oocyte meiosis;ko04914 Progesterone-mediated oocyte maturation;ko04320 Dorso-ventral axis formation","KOG0129-Predicted RNA-binding protein (RRM superfamily)[J]"]
["SRGAP2",46.16436,13.822523,-1.739758514,0,0,"down","SRGAP2","-","GO:0005096;GO:0005737;GO:0005829;GO:0005886;GO:0007165;GO:0014069;GO:0021816;GO:0030336;GO:0042803;GO:0043547;GO:0045211;GO:0045335;GO:0046847;GO:0048365;GO:0048812;GO:0060996","-","-"]
["MCM5",8.552497,2.560399,-1.739977043,{"v":9.87e-44,"d":"9.87E-44"},{"v":4.17e-43,"d":"4.17E-43"},"down","MCM5","minichromosome maintenance complex component 5","GO:0000166;GO:0003677;GO:0003688;GO:0004386;GO:0005524;GO:0005634;GO:0006260;GO:0006270;GO:0016787;GO:0042555;GO:0000166;GO:0003677;GO:0003688;GO:0004386;GO:0005524;GO:0005634;GO:0005654;GO:0006260;GO:0006270;GO:0016787;GO:0042555","K02209-ko03030 DNA replication;ko04110 Cell cycle;ko04111 Cell cycle - yeast;ko04113 Meiosis - yeast","KOG0481-DNA replication licensing factor, MCM5 component[L]"]
["CYB5A",263.596985,78.778221,-1.742465126,0,0,"down","CYB5A","cytochrome b5 type A","GO:0005783;GO:0005789;GO:0005829;GO:0016020;GO:0016021;GO:0019899;GO:0020037;GO:0031090;GO:0043231;GO:0046872;GO:0055114;GO:0016020;GO:0016021;GO:0020037;GO:0046872","-","KOG0537-Cytochrome b5[C]"]
["GPR161",15.161805,4.52692,-1.743839799,{"v":1.76e-129,"d":"1.76E-129"},{"v":1.41e-128,"d":"1.41E-128"},"down","GPR161","-","GO:0004930;GO:0005929;GO:0007165;GO:0007186;GO:0007189;GO:0016020;GO:0016021;GO:0055037;GO:1901621","K08439-ko04340 Hedgehog signaling pathway","KOG4220-Muscarinic acetylcholine receptor[T]"]
["CDH19",14.607942,4.360635,-1.7441428,{"v":4.75e-105,"d":"4.75E-105"},{"v":3.28e-104,"d":"3.28E-104"},"down","CDH19","cadherin 19","GO:0005509;GO:0005886;GO:0007155;GO:0007156;GO:0016020;GO:0016021","-","KOG4289-Cadherin EGF LAG seven-pass G-type receptor[T]"]
["BCAS1",64.122528,19.131983,-1.74484489,0,0,"down","BCAS1","-","-","-","-"]
["KLF5",239.977829,71.597145,-1.74492716,0,0,"down","KLF5","-","GO:0000122;GO:0000978;GO:0001525;GO:0003676;GO:0003677;GO:0003700;GO:0005634;GO:0005654;GO:0005794;GO:0006355;GO:0006357;GO:0006366;GO:0030033;GO:0032534;GO:0035914;GO:0043231;GO:0045600;GO:0045893;GO:0045944;GO:0060576;GO:0099156;GO:1902895;GO:1990830","-","KOG3623-Homeobox transcription factor SIP1[K]"]
["PCASP3",16.585825,4.942761,-1.746561722,{"v":2.21e-109,"d":"2.21E-109"},{"v":1.57e-108,"d":"1.57E-108"},"down","PCASP3","-","-","K07369-ko04064 NF-kappa B signaling pathway;ko04660 T cell receptor signaling pathway;ko04662 B cell receptor signaling pathway;ko05152 Tuberculosis","-"]
["RIPK4",22.511654,6.690263,-1.750537229,{"v":2.85e-154,"d":"2.85E-154"},{"v":2.58e-153,"d":"2.58E-153"},"down","RIPK4","-","GO:0002009;GO:0004672;GO:0005524;GO:0005737;GO:0006468;GO:0051092","-","KOG4177-Ankyrin[M]"]
["SELENBP1",391.476868,116.28862,-1.751217141,0,0,"down","SELENBP1","selenium binding protein 1","GO:0008430","-","KOG0918-Selenium-binding protein[P]"]
["AFAP1L1",21.042593,6.249571,-1.751483429,{"v":9.55e-150,"d":"9.55E-150"},{"v":8.47e-149,"d":"8.47E-149"},"down","AFAP1L1","-","-","-","-"]
["NCS1",79.065086,23.462059,-1.752711134,0,0,"down","NCS1","neuronal calcium sensor 1","GO:0005245;GO:0005509;GO:0005737;GO:0005794;GO:0005886;GO:0010975;GO:0014069;GO:0016020;GO:0030054;GO:0030424;GO:0030425;GO:0043231;GO:0045202;GO:0045211;GO:0046872;GO:0048471;GO:0070588","-","KOG0044-Ca2+ sensor (EF-Hand superfamily)[T]"]
["FAM160A1",17.567463,5.209735,-1.753623965,{"v":5.28e-246,"d":"5.28E-246"},{"v":6.85e-245,"d":"6.85E-245"},"down","FAM160A1","-","-","-","KOG3695-Uncharacterized conserved protein[S]"]
["FAM212A",39.816982,11.794932,-1.755216772,{"v":2.03e-105,"d":"2.03E-105"},{"v":1.4e-104,"d":"1.40E-104"},"down","FAM212A","-","-","-","-"]
["PARD6G",32.667027,9.656359,-1.758283944,{"v":1.96e-199,"d":"1.96E-199"},{"v":2.14e-198,"d":"2.14E-198"},"down","PARD6G","-","GO:0007163","K06093-ko04015 Rap1 signaling pathway;ko04390 Hippo signaling pathway;ko04391 Hippo signaling pathway -fly;ko04144 Endocytosis;ko04530 Tight junction;ko04360 Axon guidance","KOG3606-Cell polarity protein PAR6[T]"]
["PRKCI",59.090103,17.461912,-1.758704978,0,0,"down","PRKCI","protein kinase C iota","GO:0000166;GO:0004672;GO:0004674;GO:0004697;GO:0005524;GO:0005543;GO:0005622;GO:0005634;GO:0005737;GO:0005829;GO:0006468;GO:0007015;GO:0010976;GO:0015630;GO:0016301;GO:0016310;GO:0016324;GO:0016740;GO:0018105;GO:0032869;GO:0034351;GO:0035089;GO:0035556;GO:0042462;GO:0043220;GO:0043524;GO:0045171;GO:0045177;GO:0045216;GO:0046326;GO:0046872;GO:0051092;GO:0060252;GO:1903078;GO:2000353","K06069-ko04015 Rap1 signaling pathway;ko04390 Hippo signaling pathway;ko04391 Hippo signaling pathway -fly;ko04144 Endocytosis;ko04530 Tight junction;ko04611 Platelet activation;ko04910 Insulin signaling pathway","KOG0695-Serine/threonine protein kinase[T]"]
["SOWAHC",31.109613,9.168757,-1.762562381,{"v":1.94e-292,"d":"1.94E-292"},{"v":2.89e-291,"d":"2.89E-291"},"down","SOWAHC","-","-","-","KOG0514-Ankyrin repeat protein[R]"]
["KCNK3",24.35224,7.161738,-1.765672836,{"v":3.03e-172,"d":"3.03E-172"},{"v":2.98e-171,"d":"2.98E-171"},"down","KCNK3","-","GO:0005216;GO:0005252;GO:0005267;GO:0005615;GO:0005886;GO:0005887;GO:0006811;GO:0006813;GO:0008083;GO:0010469;GO:0016020;GO:0016021;GO:0022841;GO:0030322;GO:0034220;GO:0044548;GO:0071805","-","KOG4404-Tandem pore domain K+ channel TASK3/THIK-1[P]"]
["ADCYAP1R1",13.695904,4.020806,-1.76818786,{"v":9.81e-291,"d":"9.81E-291"},{"v":1.45e-289,"d":"1.45E-289"},"down","ADCYAP1R1","ADCYAP receptor type I","-","K04587-ko04024 cAMP signaling pathway;ko04080 Neuroactive ligand-receptor interaction;ko04911 Insulin secretion;ko04924 Renin secretion;ko04713 Circadian entrainment","KOG4564-Adenylate cyclase-coupled calcitonin receptor[T]"]
["GPR160",8.779615,2.576211,-1.768906917,{"v":5.57e-30,"d":"5.57E-30"},{"v":1.94e-29,"d":"1.94E-29"},"down","GPR160","G protein-coupled receptor 160","GO:0005886;GO:0016020;GO:0016021;GO:0043235","-","-"]
["COL4A6",111.063408,32.558495,-1.770277653,0,0,"down","COL4A6","-","GO:0005198;GO:0005201;GO:0005581;GO:0005587;GO:0005604;GO:0030198;GO:0038063;GO:0071230","K06237-ko04151 PI3K-Akt signaling pathway;ko04512 ECM-receptor interaction;ko04510 Focal adhesion;ko04974 Protein digestion and absorption;ko05200 Pathways in cancer;ko05222 Small cell lung cancer;ko04933 AGE-RAGE signaling pathway in diabetic complications;ko05146 Amoebiasis","-"]
["HAS2",25.931799,7.588059,-1.772919494,{"v":2.86e-144,"d":"2.86E-144"},{"v":2.47e-143,"d":"2.47E-143"},"down","HAS2","hyaluronan synthase 2","GO:0001570;GO:0005737;GO:0005887;GO:0007155;GO:0008284;GO:0016020;GO:0016021;GO:0016740;GO:0016757;GO:0030212;GO:0030213;GO:0030335;GO:0035810;GO:0036120;GO:0036302;GO:0042802;GO:0045226;GO:0050501;GO:0060349;GO:0070295;GO:0071347;GO:0071356;GO:0071498;GO:0085029;GO:0090500;GO:1900625","-","KOG2571-Chitin synthase/hyaluronan synthase (glycosyltransferases)[M]"]
["PRKX",38.19442,11.167682,-1.774032117,0,0,"down","PRKX","-","GO:0000166;GO:0001525;GO:0001935;GO:0004672;GO:0004674;GO:0004691;GO:0005524;GO:0005634;GO:0005737;GO:0006468;GO:0007155;GO:0016301;GO:0016310;GO:0016740;GO:0018105;GO:0030099;GO:0030155;GO:0030334;GO:0031589;GO:0043542;GO:0046777;GO:0060562;GO:0060993;GO:2000696","-","KOG0616-cAMP-dependent protein kinase catalytic subunit (PKA)[T]"]
["SARM1",18.15373,5.307654,-1.774119774,{"v":3.34e-143,"d":"3.34E-143"},{"v":2.87e-142,"d":"2.87E-142"},"down","SARM1","-","GO:0005737;GO:0005739;GO:0005874;GO:0007165;GO:0009749;GO:0009967;GO:0015630;GO:0030425;GO:0031315;GO:0034128;GO:0035591;GO:0042981;GO:0045202;GO:0048678;GO:0048814;GO:1901214","-","-"]
["LOC112530288",7.880219,2.303671,-1.774301032,{"v":1.76e-83,"d":"1.76E-83"},{"v":1.05e-82,"d":"1.05E-82"},"down","LOC112530288","-","-","-","-"]
["ABLIM3",33.050591,9.63341,-1.778557596,{"v":1.59e-132,"d":"1.59E-132"},{"v":1.3e-131,"d":"1.30E-131"},"down","ABLIM3","-","GO:0001725;GO:0003779;GO:0006351;GO:0007010;GO:0030027;GO:0030032;GO:0030036;GO:0045202;GO:0045944;GO:0046872;GO:0060271;GO:0098978","-","KOG1044-Actin-binding LIM Zn-finger protein Limatin involved in axon guidance[TZ]"]
["HTATIP2",23.923674,6.967809,-1.779661981,{"v":2.86e-45,"d":"2.86E-45"},{"v":1.23e-44,"d":"1.23E-44"},"down","HTATIP2","-","-","-","-"]
["CKS1B",44.072243,12.834085,-1.779889879,{"v":6.26e-50,"d":"6.26E-50"},{"v":2.82e-49,"d":"2.82E-49"},"down","CKS1B","CDC28 protein kinase regulatory subunit 1B","GO:0000307;GO:0007049;GO:0007346;GO:0016020;GO:0016021;GO:0016538;GO:0019005;GO:0019901;GO:0042393;GO:0043130;GO:0045737;GO:0045859;GO:0045893;GO:0051301;GO:0061575","-","KOG3484-Cyclin-dependent protein kinase CDC28, regulatory subunit CKS1, and related proteins[D]"]
["NDNF",85.574425,24.91279,-1.780293094,0,0,"down","NDNF","-","-","-","KOG4806-Uncharacterized conserved protein[S]"]
["DENND2C",22.175932,6.434865,-1.785012952,{"v":7.52e-128,"d":"7.52E-128"},{"v":5.96e-127,"d":"5.96E-127"},"down","DENND2C","DENN domain containing 2C","GO:0017112","-","KOG3569-RAS signaling inhibitor ST5[T]"]
["NTN4L",28.806541,8.357233,-1.785299173,0,0,"down","NTN4L","-","GO:0005576","-","-"]
["TKT",272.717896,79.001198,-1.787462938,0,0,"down","TKT","-","GO:0003824;GO:0004802;GO:0005654;GO:0008152;GO:0016604;GO:0016607;GO:0040008;GO:0042803;GO:0043209;GO:0046166;GO:0048037","K00615-ko01200 Carbon metabolism;ko01230 Biosynthesis of amino acids;ko00030 Pentose phosphate pathway;ko00710 Carbon fixation in photosynthetic organisms;ko01051 Biosynthesis of ansamycins","KOG0523-Transketolase[G]"]
["PPARG",18.454313,5.338518,-1.789446828,{"v":1.7e-158,"d":"1.70E-158"},{"v":1.57e-157,"d":"1.57E-157"},"down","PPARG","peroxisome proliferator-activated receptor gamma","-","K08530-ko04152 AMPK signaling pathway;ko03320 PPAR signaling pathway;ko04380 Osteoclast differentiation;ko04211 Longevity regulating pathway - mammal;ko05200 Pathways in cancer;ko05202 Transcriptional misregulation in cancers;ko05216 Thyroid cancer;ko05016 Huntington's disease","KOG4846-Nuclear receptor[T]"]
["LOC771494",5.298423,1.532171,-1.789985706,{"v":1.38e-68,"d":"1.38E-68"},{"v":7.35e-68,"d":"7.35E-68"},"down","LOC771494","-","-","-","-"]
["SYNM",99.842346,28.82571,-1.792295691,0,0,"down","SYNM","synemin","GO:0005198;GO:0005200;GO:0005882;GO:0005912;GO:0007010;GO:0008307;GO:0016020;GO:0017166;GO:0019215;GO:0031443;GO:0042383;GO:0043034;GO:0060053","-","KOG0977-Nuclear envelope protein lamin, intermediate filament superfamily[DY]"]
["PRKAA2",14.011232,4.039957,-1.794171974,{"v":6.02e-232,"d":"6.02E-232"},{"v":7.46e-231,"d":"7.46E-231"},"down","PRKAA2","protein kinase AMP-activated catalytic subunit alpha 2","GO:0000166;GO:0003682;GO:0004672;GO:0004674;GO:0004679;GO:0004712;GO:0005524;GO:0005623;GO:0005634;GO:0005737;GO:0005794;GO:0006468;GO:0008610;GO:0009267;GO:0010468;GO:0010494;GO:0010508;GO:0010628;GO:0010629;GO:0014850;GO:0016241;GO:0016301;GO:0016310;GO:0016607;GO:0016740;GO:0019901;GO:0030424;GO:0030425;GO:0031588;GO:0031649;GO:0031669;GO:0032007;GO:0034599;GO:0034614;GO:0035174;GO:0035404;GO:0035556;GO:0035690;GO:0042149;GO:0042493;GO:0042593;GO:0042752;GO:0043025;GO:0043066;GO:0062028;GO:0070507;GO:0071277;GO:0071333;GO:0071380;GO:1903829;GO:1904101;GO:1904428;GO:2000758","K07198-ko04068 FoxO signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04152 AMPK signaling pathway;ko04150 mTOR signaling pathway;ko04140 Regulation of autophagy;ko04910 Insulin signaling pathway;ko04922 Glucagon signaling pathway;ko04920 Adipocytokine signaling pathway;ko04921 Oxytocin signaling pathway;ko04211 Longevity regulating pathway - mammal;ko04213 Longevity regulating pathway - multiple species;ko04710 Circadian rhythm;ko05410 Hypertrophic cardiomyopathy (HCM);ko04932 Non-alcoholic fatty liver disease (NAFLD);ko04931 Insulin resistance","KOG0583-Serine/threonine protein kinase[T]"]
["RASSF7",25.209248,7.265371,-1.794844708,{"v":1.16e-149,"d":"1.16E-149"},{"v":1.02e-148,"d":"1.02E-148"},"down","RASSF7","-","GO:0005815;GO:0007165;GO:0070507","-","KOG1574-Predicted cell growth/differentiation regulator, contains RA domain[W]"]
["GREM1",105.67421,30.433935,-1.795870541,0,0,"down","GREM1","gremlin 1, DAN family BMP antagonist","GO:0000902;GO:0001525;GO:0001658;GO:0002042;GO:0002092;GO:0003257;GO:0003337;GO:0005125;GO:0005576;GO:0005615;GO:0007165;GO:0007171;GO:0007267;GO:0008284;GO:0009887;GO:0009954;GO:0009986;GO:0010717;GO:0030199;GO:0030297;GO:0030326;GO:0030502;GO:0030514;GO:0032331;GO:0033689;GO:0036122;GO:0042803;GO:0043066;GO:0043184;GO:0043542;GO:0045668;GO:0045766;GO:0045892;GO:0045893;GO:0045944;GO:0046851;GO:0048018;GO:0048263;GO:0051092;GO:0051893;GO:0051973;GO:0060173;GO:0060394;GO:0060676;GO:0061098;GO:0090090;GO:0090190;GO:0090191;GO:0090291;GO:1900086;GO:1900155;GO:1900158;GO:1901224;GO:2000273;GO:2000727","-","-"]
["ABHD3",14.50436,4.173348,-1.797209507,{"v":2.22e-92,"d":"2.22E-92"},{"v":1.42e-91,"d":"1.42E-91"},"down","ABHD3","-","GO:0004623;GO:0008970;GO:0016020;GO:0016021;GO:0046470","-","KOG1838-Alpha/beta hydrolase[R]"]
["LOC112529978",7.276394,2.088986,-1.80042084,{"v":1.24e-40,"d":"1.24E-40"},{"v":5.07e-40,"d":"5.07E-40"},"down","LOC112529978","-","-","-","-"]
["RIN3",8.975853,2.567598,-1.805629706,{"v":1.71e-73,"d":"1.71E-73"},{"v":9.49e-73,"d":"9.49E-73"},"down","RIN3","-","GO:0005769;GO:0007165;GO:0017112;GO:0017137;GO:0031410","-","KOG2320-RAS effector RIN1 (contains VPS domain)[U]"]
["SGCE",96.241928,27.46353,-1.809148471,0,0,"down","SGCE","-","GO:0003012;GO:0005794;GO:0005886;GO:0016010;GO:0016012;GO:0016020;GO:0016021;GO:0032590;GO:0061024","-","KOG4482-Sarcoglycan complex, alpha/epsilon subunits[S]"]
["GALNT5",58.404594,16.541035,-1.820032344,0,0,"down","GALNT5","-","-","K00710-ko00512 Mucin type O-glycan biosynthesis","-"]
["LOC112530493",35.671906,10.087762,-1.822182159,{"v":2.62e-130,"d":"2.62E-130"},{"v":2.1e-129,"d":"2.10E-129"},"down","LOC112530493","-","-","-","-"]
["LOC107055003",6.200288,1.752791,-1.822681248,{"v":1.58e-17,"d":"1.58E-17"},{"v":4.34e-17,"d":"4.34E-17"},"down","LOC107055003","-","-","-","-"]
["PBX3",55.384888,15.65119,-1.823220031,0,0,"down","PBX3","PBX homeobox 3","GO:0000980;GO:0002087;GO:0003677;GO:0003700;GO:0005634;GO:0005667;GO:0006355;GO:0006366;GO:0007585;GO:0008344;GO:0021516;GO:0043565;GO:0045944;GO:0048666","-","KOG0774-Transcription factor PBX and related HOX domain proteins[K]"]
["SMIM14",321.151642,90.519875,-1.826948175,0,0,"down","SMIM14","small integral membrane protein 14","GO:0005783;GO:0016020;GO:0016021","-","-"]
["SYTL2L",39.310783,11.076561,-1.82741507,0,0,"down","SYTL2L","-","GO:0005509;GO:0005544;GO:0005622;GO:0005886;GO:0006886;GO:0006906;GO:0017137;GO:0017158;GO:0019905;GO:0030276;GO:0045202;GO:0048791;GO:0070382;GO:0098793","-","-"]
["UGCG",65.871292,18.559824,-1.827466818,0,0,"down","UGCG","-","GO:0006679;GO:0008120;GO:0016020;GO:0016021;GO:0016757","K00720-ko00600 Sphingolipid metabolism","KOG2547-Ceramide glucosyltransferase[IM]"]
["BARX2",436.635376,122.928749,-1.828606667,0,0,"down","BARX2","BARX homeobox 2","-","-","KOG0488-Transcription factor BarH and related HOX domain proteins[R]"]
["SFRP2",39.00898,10.967492,-1.830572622,{"v":6.87e-137,"d":"6.87E-137"},{"v":5.73e-136,"d":"5.73E-136"},"down","SFRP2","secreted frizzled related protein 2","GO:0001569;GO:0001756;GO:0001843;GO:0002063;GO:0003151;GO:0003214;GO:0004930;GO:0005576;GO:0005615;GO:0006915;GO:0007186;GO:0007275;GO:0008047;GO:0008284;GO:0008285;GO:0008584;GO:0009952;GO:0010469;GO:0010629;GO:0010667;GO:0010719;GO:0010950;GO:0010975;GO:0016021;GO:0016055;GO:0017147;GO:0021915;GO:0030111;GO:0030154;GO:0030178;GO:0030199;GO:0030307;GO:0030308;GO:0030336;GO:0030514;GO:0031668;GO:0033138;GO:0035567;GO:0036342;GO:0042127;GO:0042493;GO:0042662;GO:0042733;GO:0042813;GO:0042981;GO:0043065;GO:0043154;GO:0043508;GO:0045600;GO:0045669;GO:0045766;GO:0045892;GO:0045944;GO:0046546;GO:0048018;GO:0048546;GO:0050680;GO:0050732;GO:0051216;GO:0060028;GO:0060070;GO:0060349;GO:0061056;GO:0061133;GO:0061185;GO:0071425;GO:0071481;GO:0090090;GO:0090175;GO:0090179;GO:0090244;GO:0090263;GO:1902042;GO:1904956;GO:2000035;GO:2000041","K02176-ko04310 Wnt signaling pathway","KOG3577-Smoothened and related G-protein-coupled receptors[T]"]
["GPR137C",13.338657,3.749688,-1.830770953,{"v":3.18e-108,"d":"3.18E-108"},{"v":2.24e-107,"d":"2.24E-107"},"down","GPR137C","-","GO:0016020;GO:0016021","-","-"]
["DSG2",136.242279,38.237984,-1.833096105,0,0,"down","DSG2","-","GO:0002934;GO:0003165;GO:0005509;GO:0005886;GO:0007155;GO:0007156;GO:0014704;GO:0016020;GO:0016021;GO:0030054;GO:0030057;GO:0043231;GO:0050839;GO:0086073;GO:0086091;GO:0098911","-","KOG1219-Uncharacterized conserved protein, contains laminin, cadherin and EGF domains[T]"]
["FAM198A",5.365411,1.501617,-1.8371718,{"v":4.7e-53,"d":"4.70E-53"},{"v":2.18e-52,"d":"2.18E-52"},"down","FAM198A","-","GO:0016020;GO:0016021;GO:0043231","-","-"]
["COL18A1",59.51371,16.655127,-1.837255701,0,0,"down","COL18A1","collagen, type XVIII, alpha 1","-","-","-"]
["PIGR",974.121216,272.384369,-1.838457392,0,0,"down","PIGR","polymeric immunoglobulin receptor","GO:0001580;GO:0001792;GO:0002415;GO:0005615;GO:0005886;GO:0007173;GO:0016020;GO:0016021;GO:0038093;GO:0043113;GO:0043235","K13073-ko04672 Intestinal immune network for IgA production","-"]
["HES4",106.418068,29.686275,-1.841875135,{"v":1.04e-291,"d":"1.04E-291"},{"v":1.54e-290,"d":"1.54E-290"},"down","HES4","hes family bHLH transcription factor 4","GO:0003677;GO:0005634;GO:0006351;GO:0006355;GO:0046983","K06054-ko03460 Fanconi anemia pathway;ko04330 Notch signaling pathway;ko05224 Breast cancer;ko04950 Maturity onset diabetes of the young","KOG4304-Transcriptional repressors of the hairy/E(spl) family (contains HLH)[K]"]
["TMPRSS4",117.897552,32.854858,-1.843355151,0,0,"down","TMPRSS4","-","GO:0004252;GO:0005044;GO:0006508;GO:0006898;GO:0008233;GO:0008236;GO:0016020;GO:0016021;GO:0016787","K09635-ko05164 Influenza A","-"]
["CIDEA",167.018509,46.459339,-1.845967458,{"v":2.03e-233,"d":"2.03E-233"},{"v":2.53e-232,"d":"2.53E-232"},"down","CIDEA","cell death-inducing DFFA-like effector a","GO:0001659;GO:0005622;GO:0005634;GO:0005737;GO:0005739;GO:0005740;GO:0005811;GO:0006629;GO:0006915;GO:0008219;GO:0010890;GO:0019915;GO:0030512;GO:0032720;GO:0035634;GO:0042803;GO:0050710;GO:0050995;GO:0120163;GO:1900118;GO:1902510","-","-"]
["SYTL4",40.844852,11.360117,-1.846176562,{"v":4.22e-204,"d":"4.22E-204"},{"v":4.74e-203,"d":"4.74E-203"},"down","SYTL4","-","-","-","KOG1028-Ca2+-dependent phospholipid-binding protein Synaptotagmin, required for synaptic vesicle and secretory granule exocytosis[TU]"]
["TP53INP1",40.373974,11.207107,-1.849011689,{"v":1e-296,"d":"1.00E-296"},{"v":1.51e-295,"d":"1.51E-295"},"down","TP53INP1","tumor protein p53 inducible nuclear protein 1","GO:0005634;GO:0005776;GO:0005829;GO:0006355;GO:0007050;GO:0008285;GO:0009408;GO:0010506;GO:0010508;GO:0010628;GO:0010629;GO:0016209;GO:0030336;GO:0034644;GO:0043065;GO:0045893;GO:0048102;GO:0048147;GO:0071361;GO:0071447;GO:0072703;GO:0098869;GO:1904761;GO:2001235","-","-"]
["CYP4V2",67.568718,18.749725,-1.849486047,0,0,"down","CYP4V2","cytochrome P450 family 4 subfamily V member 2","GO:0004497;GO:0005506;GO:0010430;GO:0016020;GO:0016021;GO:0016491;GO:0016705;GO:0020037;GO:0046872;GO:0055114","-","KOG0157-Cytochrome P450 CYP4/CYP19/CYP26 subfamilies[QI]"]
["ALCAM",135.280609,37.473259,-1.852021702,0,0,"down","ALCAM","activated leukocyte cell adhesion molecule","GO:0001772;GO:0002250;GO:0002376;GO:0005886;GO:0005887;GO:0007155;GO:0007156;GO:0007157;GO:0007411;GO:0008045;GO:0009897;GO:0016020;GO:0016021;GO:0030424;GO:0030425;GO:0031226;GO:0031290;GO:0042101;GO:0042802;GO:0042995;GO:0043025;GO:0048846;GO:0098743;GO:1990138","K06547-ko04514 Cell adhesion molecules (CAMs)","-"]
["GAP43",9.05883,2.506353,-1.853735109,{"v":7.86e-21,"d":"7.86E-21"},{"v":2.32e-20,"d":"2.32E-20"},"down","GAP43","growth associated protein 43","GO:0005516;GO:0005737;GO:0005829;GO:0005886;GO:0007275;GO:0007399;GO:0007411;GO:0010001;GO:0014069;GO:0016020;GO:0016198;GO:0030054;GO:0030154;GO:0030424;GO:0031527;GO:0032584;GO:0040008;GO:0042995;GO:0044306;GO:0045165;GO:0045202;GO:0051489;GO:0061564;GO:0071944;GO:0097060","-","-"]
["FAM212B",21.41831,5.912219,-1.857073034,{"v":1.19e-88,"d":"1.19E-88"},{"v":7.38e-88,"d":"7.38E-88"},"down","FAM212B","-","GO:0030291;GO:0071901","-","-"]
["CYP3A4",16.680023,4.599462,-1.858584254,{"v":3.08e-98,"d":"3.08E-98"},{"v":2.04e-97,"d":"2.04E-97"},"down","CYP3A4","cytochrome P450 family 3 subfamily A member 4","GO:0004497;GO:0005506;GO:0016020;GO:0016021;GO:0016491;GO:0016705;GO:0020037;GO:0046872;GO:0055114","K07424-ko00140 Steroid hormone biosynthesis;ko00591 Linoleic acid metabolism;ko00830 Retinol metabolism;ko05204 Chemical carcinogenesis","KOG0158-Cytochrome P450 CYP3/CYP5/CYP6/CYP9 subfamilies[Q]"]
["LOC107052478",9.198962,2.536211,-1.858796303,{"v":3.58e-45,"d":"3.58E-45"},{"v":1.54e-44,"d":"1.54E-44"},"down","LOC107052478","-","-","-","-"]
["CMAS",87.837547,24.215519,-1.858905842,0,0,"down","CMAS","-","GO:0008781","-","-"]
["C1QTNF1",24.939083,6.8744,-1.859102714,{"v":3.09e-89,"d":"3.09E-89"},{"v":1.93e-88,"d":"1.93E-88"},"down","C1QTNF1","-","-","-","-"]
["GAB2",36.643772,10.086011,-1.861212314,0,0,"down","GAB2","-","-","-","-"]
["LDLR",24.747583,6.783228,-1.867243739,{"v":6.75e-50,"d":"6.75E-50"},{"v":3.04e-49,"d":"3.04E-49"},"down","LDLR","low density lipoprotein receptor","GO:0005509;GO:0016020;GO:0016021","-","-"]
["LITAF",63.310215,17.35231,-1.867310563,{"v":7.38e-216,"d":"7.38E-216"},{"v":8.65e-215,"d":"8.65E-215"},"down","LITAF","lipopolysaccharide induced TNF factor","GO:0000978;GO:0001817;GO:0005654;GO:0005765;GO:0005794;GO:0005829;GO:0005886;GO:0008270;GO:0009898;GO:0032496;GO:0043231;GO:0045944;GO:0050699;GO:0071222;GO:0098559;GO:0098560;GO:0098574;GO:1901223;GO:0000139;GO:0001816;GO:0003677;GO:0005125;GO:0005634;GO:0005737;GO:0005764;GO:0005765;GO:0005768;GO:0005794;GO:0005886;GO:0006351;GO:0006355;GO:0008270;GO:0009898;GO:0010008;GO:0010469;GO:0016020;GO:0019953;GO:0031901;GO:0031902;GO:0046872;GO:0098559;GO:0098560;GO:0098574","K19363-ko04142 Lysosome","-"]
["GRB7",42.186779,11.553658,-1.868441245,{"v":1.1e-190,"d":"1.10E-190"},{"v":1.16e-189,"d":"1.16E-189"},"down","GRB7","-","GO:0005070;GO:0005829;GO:0005925;GO:0007165;GO:0009967;GO:0010494;GO:0017148;GO:0019901;GO:0030335;GO:0034063;GO:0035091;GO:0042802","-","-"]
["PPP2R5E",88.714279,24.19471,-1.874474685,0,0,"down","PPP2R5E","-","GO:0000159;GO:0005829;GO:0007165;GO:0019888;GO:0043666","K11584-ko03015 mRNA surveillance pathway;ko04071 Sphingolipid signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04152 AMPK signaling pathway;ko04113 Meiosis - yeast;ko04114 Oocyte meiosis;ko04261 Adrenergic signaling in cardiomyocytes;ko04728 Dopaminergic synapse","KOG2085-Serine/threonine protein phosphatase 2A, regulatory subunit[T]"]
["ZBTB7C",6.910859,1.884595,-1.874610523,{"v":7.8e-137,"d":"7.80E-137"},{"v":6.5e-136,"d":"6.50E-136"},"down","ZBTB7C","-","GO:0003676;GO:0005634;GO:0008285;GO:0045600;GO:0045944;GO:1903025","-","KOG4441-Proteins containing BTB/POZ and Kelch domains, involved in regulatory/signal transduction processes[TR]"]
["HPSE",14.171412,3.859758,-1.876401211,{"v":5.09e-67,"d":"5.09E-67"},{"v":2.68e-66,"d":"2.68E-66"},"down","HPSE","heparanase","GO:0005634;GO:0005654;GO:0005764;GO:0007160;GO:0010575;GO:0016020;GO:0016798;GO:0030194;GO:0030200;GO:0030305;GO:0033690;GO:0042060;GO:0043231;GO:0045121;GO:0045545;GO:0046983;GO:0051797;GO:0051798;GO:0051897;GO:0060055;GO:0061042;GO:0005576;GO:0005622;GO:0007155;GO:0007160;GO:0016020;GO:0016787;GO:0016798;GO:0030200;GO:0030305;GO:0060055","K07964-ko00531 Glycosaminoglycan degradation;ko05205 Proteoglycans in cancer","-"]
["PTGFRN",52.451038,14.274391,-1.877542128,0,0,"down","PTGFRN","-","GO:0005886;GO:0016021;GO:0034389","-","-"]
["PDLIM4",163.930206,44.604561,-1.877818568,0,0,"down","PDLIM4","PDZ and LIM domain 4","GO:0001725;GO:0005515;GO:0005634;GO:0005737;GO:0005768;GO:0005856;GO:0016020;GO:0019903;GO:0030027;GO:0030054;GO:0031532;GO:0031901;GO:0031905;GO:0031941;GO:0034777;GO:0042803;GO:0042995;GO:0043005;GO:0043197;GO:0045202;GO:0045211;GO:0046872;GO:0048471;GO:0051015;GO:0051393;GO:0055038;GO:0060173;GO:0098976","-","KOG1703-Adaptor protein Enigma and related PDZ-LIM proteins[TZ]"]
["TUBB6",273.143738,74.296768,-1.87828899,0,0,"down","TUBB6","tubulin beta 6 class V","GO:0000166;GO:0003924;GO:0005200;GO:0005525;GO:0005737;GO:0005856;GO:0005874;GO:0007010;GO:0007017","K07375-ko04145 Phagosome;ko04540 Gap junction;ko05130 Pathogenic Escherichia coli infection","KOG1375-Beta tubulin[Z]"]
["MRAP",6.424368,1.746677,-1.878941689,{"v":4.83e-80,"d":"4.83E-80"},{"v":2.82e-79,"d":"2.82E-79"},"down","MRAP","-","-","-","-"]
["LOC107054744",9.792511,2.659834,-1.880342634,{"v":9.95e-69,"d":"9.95E-69"},{"v":5.33e-68,"d":"5.33E-68"},"down","LOC107054744","-","-","-","-"]
["RHBG",35.14328,9.539751,-1.881225332,{"v":1.33e-151,"d":"1.33E-151"},{"v":1.19e-150,"d":"1.19E-150"},"down","RHBG","Rh family B glycoprotein","GO:0005887;GO:0008519;GO:0015695;GO:0015696;GO:0016020;GO:0016021;GO:0072488","-","KOG3796-Ammonium transporter RHBG[UR]"]
["VTN",59.610893,16.15749,-1.883372887,{"v":8.4e-201,"d":"8.40E-201"},{"v":9.29e-200,"d":"9.29E-200"},"down","VTN","vitronectin","GO:0005044;GO:0006898;GO:0006955;GO:0007160;GO:0010811;GO:0030198;GO:0030247;GO:0031012;GO:0048709;GO:0050840","K06251-ko04151 PI3K-Akt signaling pathway;ko04512 ECM-receptor interaction;ko04510 Focal adhesion;ko04610 Complement and coagulation cascades;ko05205 Proteoglycans in cancer","KOG1565-Gelatinase A and related matrix metalloproteases[OW]"]
["RPS6KA1L",103.362747,27.983324,-1.885077069,0,0,"down","RPS6KA1L","ribosomal protein S6 kinase A1-like","GO:0000166;GO:0000287;GO:0004672;GO:0004674;GO:0005524;GO:0005622;GO:0006468;GO:0016301;GO:0016310;GO:0016740;GO:0035556","K04373-ko04010 MAPK signaling pathway;ko04150 mTOR signaling pathway;ko04114 Oocyte meiosis;ko04914 Progesterone-mediated oocyte maturation;ko04720 Long-term potentiation;ko04722 Neurotrophin signaling pathway;ko04931 Insulin resistance","KOG0603-Ribosomal protein S6 kinase[T]"]
["RAB25",46.48447,12.552286,-1.888798677,{"v":9.1e-161,"d":"9.10E-161"},{"v":8.51e-160,"d":"8.51E-160"},"down","RAB25","-","GO:0003924;GO:0005525","-","KOG0087-GTPase Rab11/YPT3, small G protein superfamily[U]"]
["PBK",9.318257,2.511981,-1.891234569,{"v":4.52e-27,"d":"4.52E-27"},{"v":1.5e-26,"d":"1.50E-26"},"down","PBK","PDZ binding kinase","GO:0000278;GO:0001933;GO:0004672;GO:0004674;GO:0005524;GO:0005634;GO:0006468;GO:0032435;GO:0032873;GO:0034644;GO:0050728","-","KOG0581-Mitogen-activated protein kinase kinase (MAP2K)[T]"]
["PNPLA7",74.23143,19.960196,-1.894904274,0,0,"down","PNPLA7","patatin like phospholipase domain containing 7","GO:0004622;GO:0005783;GO:0006629;GO:0008152;GO:0016020;GO:0016021;GO:0016042;GO:0016787","K14676-ko00564 Glycerophospholipid metabolism","KOG2968-Predicted esterase of the alpha-beta hydrolase superfamily (Neuropathy target esterase), contains cAMP-binding domains[R]"]
["NID2",94.892204,25.512217,-1.895101292,0,0,"down","NID2","-","GO:0005509;GO:0005604;GO:0005886;GO:0007160;GO:0031012","-","-"]
["LMNB2",25.889782,6.960102,-1.895202463,{"v":7.72e-113,"d":"7.72E-113"},{"v":5.63e-112,"d":"5.63E-112"},"down","LMNB2","lamin B2","GO:0005198;GO:0005634;GO:0005635;GO:0005637;GO:0005638;GO:0005882;GO:0016020;GO:0031965","K07611-ko04210 Apoptosis;ko04214 Apoptosis - fly","KOG0977-Nuclear envelope protein lamin, intermediate filament superfamily[DY]"]
["RHOV",126.161804,33.797211,-1.900299092,0,0,"down","RHOV","-","GO:0000166;GO:0003924;GO:0005525;GO:0005622;GO:0007264","-","KOG0393-Ras-related small GTPase, Rho type[R]"]
["MAD2L1",15.92534,4.264005,-1.901043139,{"v":4.28e-47,"d":"4.28E-47"},{"v":1.87e-46,"d":"1.87E-46"},"down","MAD2L1","MAD2 mitotic arrest deficient-like 1 (yeast)","GO:0000070;GO:0000775;GO:0000776;GO:0000922;GO:0005634;GO:0005643;GO:0005654;GO:0005694;GO:0005737;GO:0005829;GO:0007093;GO:0007094;GO:0042177;GO:0042802;GO:0042803;GO:0043066;GO:0045930;GO:0048471;GO:0072686;GO:0090267;GO:1904667","K02537-ko04110 Cell cycle;ko04111 Cell cycle - yeast;ko04113 Meiosis - yeast;ko04114 Oocyte meiosis;ko04914 Progesterone-mediated oocyte maturation;ko05166 HTLV-I infection","KOG3285-Spindle assembly checkpoint protein[DZ]"]
["GADD45A",259.459686,69.343918,-1.903669137,{"v":1.91e-300,"d":"1.91E-300"},{"v":2.9e-299,"d":"2.90E-299"},"down","GADD45A","growth arrest and DNA damage inducible alpha","-","K04402-ko04010 MAPK signaling pathway;ko04068 FoxO signaling pathway;ko04110 Cell cycle;ko04210 Apoptosis;ko04115 p53 signaling pathway","KOG3406-40S ribosomal protein S12[J]"]
["PPM1H",7.429147,1.974439,-1.911753776,{"v":2.94e-134,"d":"2.94E-134"},{"v":2.42e-133,"d":"2.42E-133"},"down","PPM1H","-","GO:0003824;GO:0004721;GO:0004722;GO:0005634;GO:0005654;GO:0005737;GO:0006470;GO:0045202;GO:0098978","-","KOG1323-Serine/threonine phosphatase[T]"]
["MLPH",36.704086,9.754343,-1.911824068,{"v":1.46e-271,"d":"1.46E-271"},{"v":2.03e-270,"d":"2.03E-270"},"down","MLPH","melanophilin","GO:0003779;GO:0005622;GO:0006886;GO:0017022;GO:0017137;GO:0030050;GO:0030425;GO:0030674;GO:0030864;GO:0046872;GO:0048471","-","-"]
["FOXQ1",14.716687,3.909476,-1.912405774,{"v":1.37e-74,"d":"1.37E-74"},{"v":7.63e-74,"d":"7.63E-74"},"down","FOXQ1","-","-","-","-"]
["ACAT2",75.759674,20.111614,-1.913401257,{"v":5.36e-235,"d":"5.36E-235"},{"v":6.71e-234,"d":"6.71E-234"},"down","ACAT2","acetyl-CoA acetyltransferase 2","GO:0003824;GO:0003985;GO:0005634;GO:0005730;GO:0005737;GO:0005739;GO:0005829;GO:0006635;GO:0008152;GO:0016740;GO:0016746;GO:0016747","K00626-ko01200 Carbon metabolism;ko01212 Fatty acid metabolism;ko00620 Pyruvate metabolism;ko00630 Glyoxylate and dicarboxylate metabolism;ko00640 Propanoate metabolism;ko00650 Butanoate metabolism;ko00720 Carbon fixation pathways in prokaryotes;ko00071 Fatty acid degradation;ko00072 Synthesis and degradation of ketone bodies;ko00280 Valine, leucine and isoleucine degradation;ko00310 Lysine degradation;ko00380 Tryptophan metabolism;ko00900 Terpenoid backbone biosynthesis;ko00362 Benzoate degradation;ko02020 Two-component system","KOG1390-Acetyl-CoA acetyltransferase[I]"]
["NSDHL",12.973964,3.441261,-1.914610119,{"v":8.24e-53,"d":"8.24E-53"},{"v":3.82e-52,"d":"3.82E-52"},"down","NSDHL","-","GO:0003854;GO:0005783;GO:0005811;GO:0006694;GO:0007224;GO:0008203;GO:0016020;GO:0016021;GO:0016491;GO:0016616;GO:0055114","K07748-ko00100 Steroid biosynthesis","KOG1430-C-3 sterol dehydrogenase/3-beta-hydroxysteroid dehydrogenase and related dehydrogenases[IE]"]
["VIP",84.25563,22.339956,-1.915146747,{"v":5.84e-179,"d":"5.84E-179"},{"v":5.88e-178,"d":"5.88E-178"},"down","VIP","vasoactive intestinal peptide","GO:0005179;GO:0005576;GO:0005615;GO:0005622;GO:0007189;GO:0010467;GO:0010469;GO:0010628;GO:0032812;GO:0032880;GO:0043005;GO:0043204;GO:0045732;GO:0048242;GO:0048255;GO:0060127;GO:0070459;GO:0090277","K05264-ko04080 Neuroactive ligand-receptor interaction","-"]
["HSD17B7",20.180067,5.340292,-1.917940431,{"v":2.57e-87,"d":"2.57E-87"},{"v":1.58e-86,"d":"1.58E-86"},"down","HSD17B7","hydroxysteroid 17-beta dehydrogenase 7","GO:0000253;GO:0005783;GO:0006695;GO:0016020;GO:0016021;GO:0055114","K13373-ko00100 Steroid biosynthesis;ko00140 Steroid hormone biosynthesis;ko04913 Ovarian Steroidogenesis","KOG1478-3-keto sterol reductase[I]"]
["RASSF5",8.74978,2.314247,-1.918703891,{"v":3.84e-71,"d":"3.84E-71"},{"v":2.09e-70,"d":"2.09E-70"},"down","RASSF5","Ras association domain family member 5","GO:0005634;GO:0007165;GO:0008285;GO:0017016;GO:0031398;GO:0042981;GO:1900180","K08015-ko04014 Ras signaling pathway;ko04015 Rap1 signaling pathway;ko04670 Leukocyte transendothelial migration;ko05200 Pathways in cancer;ko05223 Non-small cell lung cancer","KOG4239-Ras GTPase effector RASSF2[T]"]
["ANXA7",292.189178,77.228828,-1.919691362,0,0,"down","ANXA7","annexin A7","GO:0005178;GO:0005509;GO:0005544;GO:0005634;GO:0005635;GO:0005789;GO:0005829;GO:0005886;GO:0006874;GO:0006914;GO:0007599;GO:0008283;GO:0008360;GO:0009651;GO:0009992;GO:0010629;GO:0030855;GO:0031982;GO:0035176;GO:0042584;GO:0048306","-","KOG0819-Annexin[U]"]
["ACTB",4423.131348,1167.65332,-1.921456088,0,0,"down","ACTB","actin, beta","GO:0000166;GO:0005524;GO:0005634;GO:0005737;GO:0005829;GO:0005856;GO:0005886;GO:0005925;GO:0015629;GO:0019894;GO:0019901;GO:0022898;GO:0030027;GO:0030863;GO:0030957;GO:0032091;GO:0032991;GO:0035267;GO:0036464;GO:0042802;GO:0043209;GO:0048488;GO:0048870;GO:0050998;GO:0051621;GO:0072749;GO:0097433;GO:0098685;GO:0098871;GO:0098973;GO:0098974;GO:0098978;GO:1903076;GO:1990904","K05692-ko04015 Rap1 signaling pathway;ko04390 Hippo signaling pathway;ko04391 Hippo signaling pathway -fly;ko04145 Phagosome;ko04810 Regulation of actin cytoskeleton;ko04210 Apoptosis;ko04510 Focal adhesion;ko04520 Adherens junction;ko04530 Tight junction;ko04611 Platelet activation;ko04670 Leukocyte transendothelial migration;ko04921 Oxytocin signaling pathway;ko04919 Thyroid hormone signaling pathway;ko04745 Phototransduction - fly;ko05205 Proteoglycans in cancer;ko05410 Hypertrophic cardiomyopathy (HCM);ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC);ko05414 Dilated cardiomyopathy (DCM);ko05416 Viral myocarditis;ko05110 Vibrio cholerae infection;ko05130 Pathogenic Escherichia coli infection;ko05132 Salmonella infection;ko05131 Shigellosis;ko05100 Bacterial invasion of epithelial cells;ko05164 Influenza A","KOG0676-Actin and related proteins[Z]"]
["B3GNT3",23.204575,6.106454,-1.926002515,{"v":1.77e-78,"d":"1.77E-78"},{"v":1.02e-77,"d":"1.02E-77"},"down","B3GNT3","-","-","-","KOG2287-Galactosyltransferases[G]"]
["C26H1orf106",34.795738,9.152324,-1.926700576,{"v":5.75e-198,"d":"5.75E-198"},{"v":6.22e-197,"d":"6.22E-197"},"down","C26H1orf106","-","GO:0000187;GO:0002221;GO:0002367;GO:0005634;GO:0005737;GO:0031398;GO:0032494;GO:0032495;GO:0032731;GO:0032733;GO:0032755;GO:0032874;GO:0034334;GO:0043123;GO:0045087;GO:0070431;GO:1903409","-","-"]
["TP53I3",12.346211,3.244263,-1.92810567,{"v":6.44e-40,"d":"6.44E-40"},{"v":2.59e-39,"d":"2.59E-39"},"down","TP53I3","-","GO:0003960;GO:0006739;GO:0016491;GO:0042803;GO:0048038;GO:0055114;GO:0070402","K10133-ko04115 p53 signaling pathway","KOG1198-Zinc-binding oxidoreductase[CR]"]
["WNT4",55.065639,14.449357,-1.930147063,{"v":5.31e-176,"d":"5.31E-176"},{"v":5.29e-175,"d":"5.29E-175"},"down","WNT4","Wnt family member 4","GO:0001656;GO:0001658;GO:0001822;GO:0001823;GO:0001837;GO:0001838;GO:0001889;GO:0003714;GO:0005102;GO:0005109;GO:0005576;GO:0005615;GO:0005737;GO:0006702;GO:0007275;GO:0007276;GO:0007548;GO:0008584;GO:0008585;GO:0009267;GO:0009986;GO:0010629;GO:0010894;GO:0014858;GO:0016055;GO:0022407;GO:0030154;GO:0030182;GO:0030237;GO:0030325;GO:0030336;GO:0030501;GO:0031012;GO:0032349;GO:0032967;GO:0033077;GO:0033080;GO:0035239;GO:0035567;GO:0038030;GO:0040037;GO:0042445;GO:0043547;GO:0045165;GO:0045596;GO:0045669;GO:0045836;GO:0045892;GO:0045893;GO:0048599;GO:0048754;GO:0048856;GO:0051145;GO:0051496;GO:0051894;GO:0060070;GO:0060126;GO:0060129;GO:0060231;GO:0060993;GO:0061036;GO:0061045;GO:0061184;GO:0061205;GO:0061369;GO:0071560;GO:0072006;GO:0072033;GO:0072034;GO:0072164;GO:0072174;GO:0072210;GO:0072273;GO:1902811;GO:2000019;GO:2000066;GO:2000225;GO:2001234","K00408-ko04310 Wnt signaling pathway;ko04390 Hippo signaling pathway;ko04150 mTOR signaling pathway;ko04550 Signaling pathways regulating pluripotency of stem cells;ko04919 Thyroid hormone signaling pathway;ko04916 Melanogenesis;ko04360 Axon guidance;ko05200 Pathways in cancer;ko05205 Proteoglycans in cancer;ko05217 Basal cell carcinoma;ko05224 Breast cancer;ko05166 HTLV-I infection","KOG3913-Wnt family of developmental regulators[T]"]
["KIT",12.49396,3.278438,-1.930150299,{"v":2.74e-140,"d":"2.74E-140"},{"v":2.32e-139,"d":"2.32E-139"},"down","KIT","KIT proto-oncogene receptor tyrosine kinase","GO:0000166;GO:0000187;GO:0001541;GO:0002020;GO:0002318;GO:0002320;GO:0002327;GO:0002371;GO:0002551;GO:0002573;GO:0004672;GO:0004713;GO:0004714;GO:0005020;GO:0005524;GO:0005615;GO:0005622;GO:0005886;GO:0005911;GO:0006468;GO:0006687;GO:0006954;GO:0007169;GO:0007283;GO:0007286;GO:0008284;GO:0008360;GO:0008584;GO:0009314;GO:0009897;GO:0009986;GO:0010628;GO:0016020;GO:0016021;GO:0016301;GO:0016310;GO:0016740;GO:0018108;GO:0019221;GO:0019955;GO:0030032;GO:0030097;GO:0030217;GO:0030218;GO:0030318;GO:0031532;GO:0032762;GO:0035162;GO:0035234;GO:0035556;GO:0035701;GO:0035855;GO:0038093;GO:0038109;GO:0038162;GO:0042531;GO:0042629;GO:0042803;GO:0043069;GO:0043303;GO:0043406;GO:0043410;GO:0043473;GO:0046427;GO:0046777;GO:0046872;GO:0048066;GO:0048070;GO:0048565;GO:0048863;GO:0050910;GO:0051091;GO:0060326;GO:0060374;GO:0097067;GO:0097324;GO:0097326;GO:1905065","K05091-ko04014 Ras signaling pathway;ko04015 Rap1 signaling pathway;ko04072 Phospholipase D signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04060 Cytokine-cytokine receptor interaction;ko04144 Endocytosis;ko04640 Hematopoietic cell lineage;ko04916 Melanogenesis;ko05200 Pathways in cancer;ko05230 Central carbon metabolism in cancer;ko05221 Acute myeloid leukemia;ko05224 Breast cancer","KOG0200-Fibroblast/platelet-derived growth factor receptor and related receptor tyrosine kinases[T]"]
["ECM1",771.875244,202.488327,-1.930528945,0,0,"down","ECM1","-","GO:0005576;GO:0005615;GO:0007165","-","-"]
["NGFR",12.669562,3.318619,-1.932711737,{"v":7.3e-40,"d":"7.30E-40"},{"v":2.94e-39,"d":"2.94E-39"},"down","NGFR","nerve growth factor receptor","GO:0007165;GO:0016020;GO:0016021;GO:0005031;GO:0005035;GO:0005516;GO:0005634;GO:0005886;GO:0005887;GO:0006915;GO:0006919;GO:0006954;GO:0006955;GO:0007165;GO:0007266;GO:0007275;GO:0007399;GO:0007411;GO:0010977;GO:0015026;GO:0016020;GO:0016021;GO:0030154;GO:0031625;GO:0032496;GO:0032922;GO:0033209;GO:0042127;GO:0042981;GO:0043005;GO:0043121;GO:0048406;GO:0048511;GO:0051402;GO:0097190;GO:1900182;GO:1902895;GO:1903588;GO:1904646","K02583-ko04014 Ras signaling pathway;ko04015 Rap1 signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04060 Cytokine-cytokine receptor interaction;ko04215 Apoptosis - multiple species;ko04722 Neurotrophin signaling pathway;ko05202 Transcriptional misregulation in cancers","-"]
["SYTL1",105.676407,27.599348,-1.93694723,0,0,"down","SYTL1","synaptotagmin like 1","GO:0006887;GO:0016020;GO:0016021","-","KOG1028-Ca2+-dependent phospholipid-binding protein Synaptotagmin, required for synaptic vesicle and secretory granule exocytosis[TU]"]
["PTGDS",4367.781738,1139.729614,-1.938209161,0,0,"down","PTGDS","prostaglandin D2 synthase 21kDa (brain)","GO:0001516;GO:0004667;GO:0005501;GO:0005576;GO:0036094;GO:0045187;GO:2000255","K01830-ko00590 Arachidonic acid metabolism","-"]
["BCL11A",10.679766,2.785084,-1.939087291,{"v":5.6e-131,"d":"5.60E-131"},{"v":4.52e-130,"d":"4.52E-130"},"down","BCL11A","B-cell CLL/lymphoma 11A","GO:0003676;GO:0005654","-","KOG3623-Homeobox transcription factor SIP1[K]"]
["MKI67",8.050941,2.090748,-1.945138233,{"v":3.04e-107,"d":"3.04E-107"},{"v":2.13e-106,"d":"2.13E-106"},"down","MKI67","-","-","-","-"]
["EPHB3",60.136677,15.608152,-1.945945418,0,0,"down","EPHB3","-","GO:0000166;GO:0004672;GO:0004713;GO:0004714;GO:0005003;GO:0005524;GO:0005886;GO:0005887;GO:0006468;GO:0007169;GO:0007275;GO:0007399;GO:0007411;GO:0007413;GO:0016020;GO:0016021;GO:0016301;GO:0016310;GO:0016477;GO:0016740;GO:0018108;GO:0022407;GO:0030425;GO:0034446;GO:0042995;GO:0043087;GO:0046777;GO:0048013;GO:0050770;GO:0051965;GO:0060996;GO:0060997;GO:0000166;GO:0001525;GO:0001655;GO:0004672;GO:0004713;GO:0005003;GO:0005524;GO:0005887;GO:0006468;GO:0007169;GO:0007411;GO:0007413;GO:0008046;GO:0016020;GO:0016021;GO:0016301;GO:0016310;GO:0016477;GO:0016740;GO:0018108;GO:0021952;GO:0022038;GO:0022407;GO:0031290;GO:0034446;GO:0043087;GO:0046777;GO:0048013;GO:0048538;GO:0048546;GO:0050770;GO:0051965;GO:0060021;GO:0060996;GO:0060997","-","KOG0196-Tyrosine kinase, EPH (ephrin) receptor family[T]"]
["TCF24",28.019079,7.269414,-1.946498559,{"v":7.65e-102,"d":"7.65E-102"},{"v":5.18e-101,"d":"5.18E-101"},"down","TCF24","-","-","-","KOG4029-Transcription factor HAND2/Transcription factor TAL1/TAL2/LYL1[K]"]
["SIGMAR1",85.321304,22.120451,-1.947525215,{"v":8.38e-279,"d":"8.38E-279"},{"v":1.19e-277,"d":"1.19E-277"},"down","SIGMAR1","sigma non-opioid intracellular receptor 1","GO:0005634;GO:0005635;GO:0005637;GO:0005640;GO:0005783;GO:0005789;GO:0006869;GO:0014069;GO:0016020;GO:0016021;GO:0031410;GO:0036474;GO:0038023;GO:0043523;GO:0070207","-","KOG4143-Sigma receptor and C-8 sterol isomerase[T]"]
["IDI1",42.138916,10.907589,-1.949820957,{"v":6.7e-205,"d":"6.70E-205"},{"v":7.57e-204,"d":"7.57E-204"},"down","IDI1","-","GO:0004452;GO:0005737;GO:0008299;GO:0009240;GO:0016787","K01823-ko00900 Terpenoid backbone biosynthesis","-"]
["SPON2",152.40065,39.299778,-1.955275988,0,0,"down","SPON2","-","GO:0001530;GO:0002448;GO:0003823;GO:0005615;GO:0008228;GO:0031012;GO:0032496;GO:0032755;GO:0032760;GO:0042742;GO:0043152;GO:0045087;GO:0050832;GO:0051607;GO:0060907;GO:0071222","-","KOG3539-Spondins, extracellular matrix proteins[W]"]
["LOC769704",150.182556,38.656815,-1.957922569,0,0,"down","LOC769704","-","GO:0004104;GO:0016787","K01044-ko00983 Drug metabolism - other enzymes","-"]
["GUCY1A3",37.970486,9.74485,-1.962166581,{"v":7.24e-273,"d":"7.24E-273"},{"v":1.01e-271,"d":"1.01E-271"},"down","GUCY1A3","-","GO:0000166;GO:0004383;GO:0006182;GO:0008074;GO:0008217;GO:0009190;GO:0010750;GO:0016829;GO:0016849;GO:0020037;GO:0035556;GO:0052565;GO:0060087;GO:0098925;GO:0098978;GO:0098982","K12318-ko00230 Purine metabolism;ko04022 cGMP - PKG signaling pathway;ko04540 Gap junction;ko04611 Platelet activation;ko04921 Oxytocin signaling pathway;ko04924 Renin secretion;ko04270 Vascular smooth muscle contraction;ko04970 Salivary secretion;ko04730 Long-term depression;ko04713 Circadian entrainment","-"]
["MIR6587",35.624096,9.12082,-1.965617965,0.013210333,0.01821392,"down","MIR6587","microRNA 6587","-","-","-"]
["LOC422090",342.938965,87.789108,-1.965837973,0,0,"down","LOC422090","uncharacterized LOC422090","-","-","-"]
["C1QTNF6",15.803973,4.041049,-1.967485536,{"v":1.49e-142,"d":"1.49E-142"},{"v":1.27e-141,"d":"1.27E-141"},"down","C1QTNF6","-","GO:0005576;GO:0005581","-","-"]
["NRTN",5.29265,1.35318,-1.967636493,{"v":3.51e-53,"d":"3.51E-53"},{"v":1.63e-52,"d":"1.63E-52"},"down","NRTN","neurturin","GO:0001755;GO:0005576;GO:0007169;GO:0008083;GO:0010469;GO:0021675;GO:0031175","-","-"]
["PIGA",15.854177,4.050107,-1.96883106,{"v":4.53e-156,"d":"4.53E-156"},{"v":4.13e-155,"d":"4.13E-155"},"down","PIGA","phosphatidylinositol glycan anchor biosynthesis class A","GO:0000506;GO:0005789;GO:0006506;GO:0016020;GO:0016021;GO:0017176;GO:1990830","K03857-ko00563 Glycosylphosphatidylinositol(GPI)-anchor biosynthesis","KOG1111-N-acetylglucosaminyltransferase complex, subunit PIG-A/SPT14, required for phosphatidylinositol biosynthesis/Sulfolipid synthase[MOI]"]
["CREB3L1",66.230583,16.8943,-1.970960983,0,0,"down","CREB3L1","-","GO:0000122;GO:0000790;GO:0001227;GO:0003677;GO:0003700;GO:0005634;GO:0005783;GO:0006355;GO:0010629;GO:0016020;GO:0030968;GO:0032967;GO:0035497;GO:0040037;GO:0045892;GO:0045944;GO:0046332;GO:1903671","K09048-ko04668 TNF signaling pathway;ko04024 cAMP signaling pathway;ko04022 cGMP - PKG signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04152 AMPK signaling pathway;ko04911 Insulin secretion;ko04922 Glucagon signaling pathway;ko04915 Estrogen signaling pathway;ko04918 Thyroid hormone synthesis;ko04916 Melanogenesis;ko04925 Aldosterone synthesis and secretion;ko04261 Adrenergic signaling in cardiomyocytes;ko04962 Vasopressin-regulated water reabsorption;ko04725 Cholinergic synapse;ko04728 Dopaminergic synapse;ko04211 Longevity regulating pathway - mammal;ko05203 Viral carcinogenesis;ko05215 Prostate cancer;ko05016 Huntington's disease;ko05030 Cocaine addiction;ko05031 Amphetamine addiction;ko05034 Alcoholism;ko04931 Insulin resistance;ko05161 Hepatitis B","KOG0709-CREB/ATF family transcription factor[K]"]
["PER3",17.300642,4.405108,-1.97357628,{"v":1.17e-180,"d":"1.17E-180"},{"v":1.18e-179,"d":"1.18E-179"},"down","PER3","period circadian clock 3","GO:0000122;GO:0005634;GO:0005737;GO:0007623;GO:0019900;GO:0031625;GO:0032922;GO:0045187;GO:0050821","-","KOG3753-Circadian clock protein period[T]"]
["TMOD2",5.207598,1.322052,-1.977839161,{"v":3.01e-06,"d":"3.01E-06"},{"v":5.54e-06,"d":"5.54E-06"},"down","TMOD2","-","GO:0005523;GO:0005865;GO:0006936;GO:0007015;GO:0007270;GO:0007611;GO:0030239;GO:0045745;GO:0051694","-","KOG3735-Tropomodulin and leiomodulin[Z]"]
["FDFT1",73.04924,18.526651,-1.97926715,0,0,"down","FDFT1","farnesyl-diphosphate farnesyltransferase 1","GO:0004310;GO:0005783;GO:0005789;GO:0006695;GO:0006696;GO:0008610;GO:0009058;GO:0016021;GO:0016740;GO:0016765;GO:0045338;GO:0051996","K00801-ko00100 Steroid biosynthesis;ko00909 Sesquiterpenoid and triterpenoid biosynthesis","KOG1459-Squalene synthetase[I]"]
["CHMP4C",95.503845,24.204985,-1.980254617,0,0,"down","CHMP4C","charged multivesicular body protein 4C","GO:0000920;GO:0006997;GO:0007034;GO:0007080;GO:0009838;GO:0010824;GO:0030496;GO:0032466;GO:0042803;GO:0044878;GO:0050792;GO:0090543;GO:0090611;GO:1901673;GO:1902188","K12194-ko04144 Endocytosis","KOG1656-Protein involved in glucose derepression and pre-vacuolar endosome protein sorting[U]"]
["RHOBTB2",54.714619,13.844363,-1.982627678,0,0,"down","RHOBTB2","-","GO:0000166;GO:0003924;GO:0005525;GO:0005622;GO:0007264","K07868-ko04120 Ubiquitin mediated proteolysis","KOG0393-Ras-related small GTPase, Rho type[R]"]
["SEPT5",116.69088,29.517086,-1.983069604,0,0,"down","SEPT5","septin 5","GO:0000166;GO:0005525;GO:0008021;GO:0017157","-","KOG2655-Septin family protein (P-loop GTPase)[DZU]"]
["SYT16",11.242061,2.838851,-1.985527513,{"v":3.58e-115,"d":"3.58E-115"},{"v":2.64e-114,"d":"2.64E-114"},"down","SYT16","-","GO:0005509;GO:0005543;GO:0005544;GO:0005886;GO:0006887;GO:0006906;GO:0017158;GO:0019905;GO:0030276;GO:0042803;GO:0045202;GO:0046982;GO:0048791;GO:0098793","-","KOG1028-Ca2+-dependent phospholipid-binding protein Synaptotagmin, required for synaptic vesicle and secretory granule exocytosis[TU]"]
["LOC107053293",6.053755,1.527521,-1.986638075,{"v":4.62e-26,"d":"4.62E-26"},{"v":1.51e-25,"d":"1.51E-25"},"down","LOC107053293","-","-","-","-"]
["LOC112532581",9.188651,2.313627,-1.989696779,{"v":7.79e-21,"d":"7.79E-21"},{"v":2.3e-20,"d":"2.30E-20"},"down","LOC112532581","-","-","-","-"]
["ELF3",336.190033,84.600227,-1.990543514,0,0,"down","ELF3","-","GO:0000978;GO:0000981;GO:0003677;GO:0003700;GO:0003713;GO:0005634;GO:0005654;GO:0005794;GO:0005829;GO:0006355;GO:0006357;GO:0006366;GO:0006954;GO:0009653;GO:0030154;GO:0030198;GO:0030855;GO:0043565;GO:0045892;GO:0045893;GO:0045944","-","KOG3804-Transcription factor NERF and related proteins, contain ETS domain[K]"]
["DGKG",9.434545,2.37397,-1.990651239,{"v":5.11e-120,"d":"5.11E-120"},{"v":3.87e-119,"d":"3.87E-119"},"down","DGKG","-","GO:0000166;GO:0003951;GO:0004143;GO:0005509;GO:0005524;GO:0005622;GO:0007165;GO:0007205;GO:0008152;GO:0016301;GO:0016310;GO:0016740;GO:0035556;GO:0046486;GO:0046834","K00901-ko00561 Glycerolipid metabolism;ko00564 Glycerophospholipid metabolism;ko04070 Phosphatidylinositol signaling system;ko04072 Phospholipase D signaling pathway;ko05231 Choline metabolism in cancer","KOG1169-Diacylglycerol kinase[IT]"]
["ANXA4",205.599075,51.686562,-1.991972626,0,0,"down","ANXA4","-","GO:0005509;GO:0005544;GO:0005634;GO:0005737;GO:0005886;GO:0006357;GO:0007219;GO:0009986;GO:0012506;GO:0030855;GO:0031965;GO:0032088;GO:0042802;GO:0048306;GO:0048471;GO:0051059;GO:2000483","-","-"]
["SMIM5",74.423943,18.674963,-1.994661442,{"v":1.47e-290,"d":"1.47E-290"},{"v":2.16e-289,"d":"2.16E-289"},"down","SMIM5","small integral membrane protein 5","GO:0016020;GO:0016021","-","-"]
["PALLD",165.565338,41.539494,-1.994845121,0,0,"down","PALLD","-","-","-","-"]
["KCNQ4",5.439201,1.36396,-1.995593404,{"v":3.72e-43,"d":"3.72E-43"},{"v":1.56e-42,"d":"1.56E-42"},"down","KCNQ4","-","GO:0005216;GO:0005249;GO:0005267;GO:0006811;GO:0006813;GO:0007605;GO:0008076;GO:0016020;GO:0016021;GO:0042472;GO:0055085;GO:0071805","-","KOG1419-Voltage-gated K+ channel KCNQ[P]"]
["LZTS1",11.657282,2.923066,-1.995677141,{"v":5.99e-89,"d":"5.99E-89"},{"v":3.73e-88,"d":"3.73E-88"},"down","LZTS1","-","GO:0008017;GO:0016242;GO:0044772","-","-"]
["VAV3",32.230026,8.074899,-1.996889232,0,0,"down","VAV3","vav 3 guanine nucleotide exchange factor","GO:0005085;GO:0005089;GO:0005154;GO:0005737;GO:0005886;GO:0006906;GO:0006974;GO:0007229;GO:0007264;GO:0008361;GO:0016477;GO:0030031;GO:0030032;GO:0030593;GO:0030676;GO:0030890;GO:0035023;GO:0035556;GO:0042493;GO:0043087;GO:0043552;GO:0045785;GO:0046872;GO:0050853","K05730-ko04024 cAMP signaling pathway;ko04810 Regulation of actin cytoskeleton;ko04510 Focal adhesion;ko04650 Natural killer cell mediated cytotoxicity;ko04660 T cell receptor signaling pathway;ko04662 B cell receptor signaling pathway;ko04664 Fc epsilon RI signaling pathway;ko04666 Fc gamma R-mediated phagocytosis;ko04670 Leukocyte transendothelial migration;ko04062 Chemokine signaling pathway","KOG2996-Rho guanine nucleotide exchange factor VAV3[T]"]
["ALDOC",610.589355,152.95578,-1.997087812,0,0,"down","ALDOC","aldolase, fructose-bisphosphate C","GO:0003824;GO:0004332;GO:0005829;GO:0006094;GO:0006096;GO:0008092;GO:0016829;GO:0030388;GO:0030855","K01623-ko01200 Carbon metabolism;ko01230 Biosynthesis of amino acids;ko00010 Glycolysis / Gluconeogenesis;ko00030 Pentose phosphate pathway;ko00051 Fructose and mannose metabolism;ko00710 Carbon fixation in photosynthetic organisms;ko00680 Methane metabolism","KOG1557-Fructose-biphosphate aldolase[G]"]
["RNF32",11.537691,2.887975,-1.998224373,{"v":9.7e-150,"d":"9.70E-150"},{"v":8.61e-149,"d":"8.61E-149"},"down","RNF32","-","GO:0005768;GO:0016235","-","KOG1941-Acetylcholine receptor-associated protein of the synapse (rapsyn)[W]"]
["SNX5",74.932281,18.75374,-1.998409032,{"v":1.81e-305,"d":"1.81E-305"},{"v":2.79e-304,"d":"2.79E-304"},"down","SNX5","sorting nexin 5","GO:0005768;GO:0005829;GO:0006886;GO:0006897;GO:0006907;GO:0015031;GO:0016050;GO:0019898;GO:0030904;GO:0031234;GO:0031313;GO:0031901;GO:0034452;GO:0035091;GO:0042147;GO:0070685;GO:0097422","K17920-ko04144 Endocytosis","KOG1660-Sorting nexin SNX6/TFAF2, contains PX domain[V]"]
["S100A10",1423.873291,354.395233,-2.006389665,0,0,"down","S100A10","S100 calcium binding protein A10","GO:0001765;GO:0005509;GO:0006900;GO:0016020;GO:0016021;GO:0019897;GO:0042803;GO:0043547;GO:0044325;GO:0045121;GO:0051099;GO:0051290;GO:0051496;GO:0051894;GO:0072659;GO:1900026","-","-"]
["ARF6",259.340424,64.530174,-2.006801279,0,0,"down","ARF6","ADP ribosylation factor 6","GO:0000166;GO:0001726;GO:0001889;GO:0005525;GO:0005622;GO:0005737;GO:0005768;GO:0005794;GO:0005829;GO:0005886;GO:0005938;GO:0007399;GO:0010008;GO:0010975;GO:0015031;GO:0016020;GO:0016192;GO:0030139;GO:0030154;GO:0030838;GO:0030866;GO:0031527;GO:0031996;GO:0032154;GO:0032456;GO:0032587;GO:0033028;GO:0034394;GO:0035020;GO:0036010;GO:0042995;GO:0043209;GO:0047485;GO:0051489;GO:0051549;GO:0055038;GO:0060998;GO:0090162;GO:0090543;GO:0097178;GO:0097284;GO:1903078;GO:1903393;GO:2000009;GO:0000166;GO:0001726;GO:0001889;GO:0005525;GO:0005622;GO:0005737;GO:0005768;GO:0005886;GO:0005938;GO:0010975;GO:0030139;GO:0030838;GO:0030866;GO:0031527;GO:0031996;GO:0032154;GO:0032456;GO:0033028;GO:0034394;GO:0035020;GO:0036010;GO:0043209;GO:0047485;GO:0051489;GO:0051549;GO:0055038;GO:0060998;GO:0090162;GO:0090543;GO:0097178;GO:0097284;GO:1903078;GO:1903393;GO:2000009","K07941-ko04014 Ras signaling pathway;ko04072 Phospholipase D signaling pathway;ko04144 Endocytosis;ko04666 Fc gamma R-mediated phagocytosis","KOG0071-GTP-binding ADP-ribosylation factor Arf6 (dArf3)[U]"]
["LOC112529982",5.204274,1.291273,-2.010902874,{"v":4.77e-12,"d":"4.77E-12"},{"v":1.13e-11,"d":"1.13E-11"},"down","LOC112529982","-","-","-","-"]
["USP43",70.216057,17.391869,-2.013388005,0,0,"down","USP43","-","-","-","KOG1870-Ubiquitin C-terminal hydrolase[O]"]
["LOC101751371",104.41526,25.862009,-2.013426318,0,0,"down","LOC101751371","-","-","-","-"]
["NT5E",34.46265,8.53264,-2.013969556,{"v":1.44e-306,"d":"1.44E-306"},{"v":2.23e-305,"d":"2.23E-305"},"down","NT5E","-","GO:0000166;GO:0009166;GO:0016787;GO:0016788;GO:0046872","K19970-ko00230 Purine metabolism;ko00240 Pyrimidine metabolism;ko00760 Nicotinate and nicotinamide metabolism","KOG4419-5' nucleotidase[F]"]
["KIF23",10.757839,2.655572,-2.018293752,{"v":7.82e-92,"d":"7.82E-92"},{"v":4.97e-91,"d":"4.97E-91"},"down","KIF23","kinesin family member 23","GO:0000166;GO:0000910;GO:0000915;GO:0003774;GO:0003777;GO:0005524;GO:0005622;GO:0005623;GO:0005874;GO:0007018;GO:0008017;GO:0072383;GO:0000166;GO:0000281;GO:0000910;GO:0000915;GO:0003774;GO:0003777;GO:0005524;GO:0005634;GO:0005654;GO:0005813;GO:0005819;GO:0005871;GO:0005874;GO:0007018;GO:0008017;GO:0016887;GO:0030496;GO:0032467;GO:0045171;GO:0051256;GO:0072383;GO:0072686;GO:0097149","-","KOG0247-Kinesin-like protein[Z]"]
["ERO1A",76.300377,18.826225,-2.018946443,0,0,"down","ERO1A","endoplasmic reticulum oxidoreductase 1 alpha","GO:0003756;GO:0005783;GO:0005789;GO:0006457;GO:0006464;GO:0015035;GO:0016491;GO:0016671;GO:0019471;GO:0022417;GO:0030198;GO:0030968;GO:0034975;GO:0034976;GO:0045454;GO:0051085;GO:0051209;GO:0055114;GO:0070059","K10950-ko04141 Protein processing in endoplasmic reticulum;ko05110 Vibrio cholerae infection","KOG2608-Endoplasmic reticulum membrane-associated oxidoreductin involved in disulfide bond formation[OU]"]
["TP53I11",111.174988,27.339109,-2.023794119,0,0,"down","TP53I11","tumor protein p53 inducible protein 11","GO:0016020;GO:0016021","-","-"]
["ATP2B4",74.512131,18.306297,-2.025135332,0,0,"down","ATP2B4","-","GO:0000166;GO:0005388;GO:0005516;GO:0005524;GO:0005886;GO:0005887;GO:0006357;GO:0006811;GO:0006816;GO:0006874;GO:0010751;GO:0016020;GO:0016021;GO:0016787;GO:0030018;GO:0030165;GO:0030315;GO:0030317;GO:0030346;GO:0033138;GO:0036126;GO:0036487;GO:0042383;GO:0043231;GO:0045019;GO:0050998;GO:0051001;GO:0051599;GO:0070588;GO:0070885;GO:0071872;GO:0098736;GO:0099132;GO:0140199;GO:1900082;GO:1902806;GO:1903243;GO:1903249;GO:2000481","K05850-ko04020 Calcium signaling pathway;ko04024 cAMP signaling pathway;ko04022 cGMP - PKG signaling pathway;ko04261 Adrenergic signaling in cardiomyocytes;ko04970 Salivary secretion;ko04972 Pancreatic secretion","KOG0204-Calcium transporting ATPase[P]"]
["NT5C1B",306.862366,75.276543,-2.027319442,0,0,"down","NT5C1B","-","GO:0000166;GO:0000287;GO:0005737;GO:0005829;GO:0008253;GO:0009116;GO:0009117;GO:0016311","K01081-ko00230 Purine metabolism;ko00240 Pyrimidine metabolism;ko00760 Nicotinate and nicotinamide metabolism","-"]
["SH3BGRL",214.098053,52.464466,-2.02885915,0,0,"down","SH3BGRL","SH3 domain binding glutamate rich protein like","-","-","KOG4023-Uncharacterized conserved protein[S]"]
["RGS10",59.620316,14.575752,-2.032233704,0,0,"down","RGS10","-","GO:0001965;GO:0005096;GO:0005634;GO:0005737;GO:0005829;GO:0005886;GO:0007213;GO:0008277;GO:0043547","-","KOG3589-G protein signaling regulators[T]"]
["LAMB3",10.405284,2.540417,-2.034179108,{"v":2.3e-149,"d":"2.30E-149"},{"v":2.04e-148,"d":"2.04E-148"},"down","LAMB3","-","GO:0005604;GO:0005610;GO:0035987","K06244-ko04151 PI3K-Akt signaling pathway;ko04512 ECM-receptor interaction;ko04510 Focal adhesion;ko05200 Pathways in cancer;ko05222 Small cell lung cancer;ko05146 Amoebiasis;ko05145 Toxoplasmosis","KOG0994-Extracellular matrix glycoprotein Laminin subunit beta[W]"]
["SLC13A2",6.726239,1.639157,-2.036845999,{"v":7.56e-51,"d":"7.56E-51"},{"v":3.43e-50,"d":"3.43E-50"},"down","SLC13A2","-","GO:0005215;GO:0005887;GO:0006814;GO:0016020;GO:0016021;GO:0055085;GO:0098656","-","KOG1281-Na+/dicarboxylate, Na+/tricarboxylate and phosphate transporters[P]"]
["NEBL",12.671769,3.085628,-2.037981893,{"v":4.09e-41,"d":"4.09E-41"},{"v":1.68e-40,"d":"1.68E-40"},"down","NEBL","nebulette","-","-","KOG1702-Nebulin repeat protein[Z]"]
["TMEM267",10.981179,2.673108,-2.038442926,{"v":6.97e-43,"d":"6.97E-43"},{"v":2.91e-42,"d":"2.91E-42"},"down","TMEM267","-","GO:0016020;GO:0016021","-","-"]
["SEMA4B",43.381535,10.555905,-2.03903083,0,0,"down","SEMA4B","-","GO:0005615;GO:0005886;GO:0016020;GO:0016021;GO:0038191;GO:0045202;GO:0050919","-","-"]
["MIR7444",24.925665,6.061723,-2.039832163,0.029679515,0.039003526,"down","MIR7444","microRNA 7444","-","-","-"]
["MAP2K6",5.055465,1.228661,-2.04075688,{"v":1.76e-20,"d":"1.76E-20"},{"v":5.16e-20,"d":"5.16E-20"},"down","MAP2K6","-","GO:0000165;GO:0000166;GO:0000187;GO:0004672;GO:0004674;GO:0004708;GO:0005524;GO:0005634;GO:0005737;GO:0005829;GO:0006468;GO:0007346;GO:0019901;GO:0023014;GO:0031098;GO:0032147;GO:0042981;GO:0060048;GO:0120163","K04433-ko04015 Rap1 signaling pathway;ko04010 MAPK signaling pathway;ko04668 TNF signaling pathway;ko04620 Toll-like receptor signaling pathway;ko04664 Fc epsilon RI signaling pathway;ko04912 GnRH signaling pathway;ko04750 Inflammatory mediator regulation of TRP channels;ko04380 Osteoclast differentiation;ko04212 Longevity regulating pathway - worm;ko05014 Amyotrophic lateral sclerosis (ALS);ko05164 Influenza A;ko05169 Epstein-Barr virus infection;ko05145 Toxoplasmosis","KOG0984-Mitogen-activated protein kinase (MAPK) kinase MKK3/MKK6[T]"]
["SLC52A3",46.408676,11.197336,-2.051239003,{"v":5.64e-211,"d":"5.64E-211"},{"v":6.48e-210,"d":"6.48E-210"},"down","SLC52A3","-","GO:0005887;GO:0016020;GO:0016021;GO:0032217;GO:0032218;GO:0034605","-","KOG4255-Uncharacterized conserved protein[S]"]
["ADAMTS8",23.918985,5.761176,-2.053720933,0,0,"down","ADAMTS8","-","GO:0004222;GO:0006508;GO:0008237;GO:0008270;GO:0062023","-","KOG3538-Disintegrin metalloproteinases with thrombospondin repeats[O]"]
["KCNMA1",26.922239,6.475246,-2.055791489,0,0,"down","KCNMA1","potassium calcium-activated channel subfamily M alpha 1","GO:0005216;GO:0005244;GO:0005249;GO:0005267;GO:0006811;GO:0006813;GO:0008076;GO:0016020;GO:0016021;GO:0034765;GO:0055085;GO:0060072;GO:0071805;GO:0005216;GO:0005244;GO:0005249;GO:0005267;GO:0005515;GO:0006811;GO:0006813;GO:0008076;GO:0016020;GO:0016021;GO:0034765;GO:0046872;GO:0055085;GO:0060072;GO:0071805","K04936-ko04022 cGMP - PKG signaling pathway;ko04911 Insulin secretion;ko04924 Renin secretion;ko04270 Vascular smooth muscle contraction;ko04970 Salivary secretion;ko04972 Pancreatic secretion","-"]
["RAB27A",145.96965,35.025837,-2.059177003,0,0,"down","RAB27A","RAB27A, member RAS oncogene family","GO:0003924;GO:0005525","-","KOG0081-GTPase Rab27, small G protein superfamily[U]"]
["FAM110A",20.402956,4.882123,-2.063197639,{"v":1.15e-135,"d":"1.15E-135"},{"v":9.55e-135,"d":"9.55E-135"},"down","FAM110A","-","-","-","-"]
["LOC112532660",12.571765,3.006532,-2.064014991,{"v":4.32e-46,"d":"4.32E-46"},{"v":1.87e-45,"d":"1.87E-45"},"down","LOC112532660","-","-","-","-"]
["TNS4",6.444458,1.538455,-2.066576783,{"v":1.53e-57,"d":"1.53E-57"},{"v":7.45e-57,"d":"7.45E-57"},"down","TNS4","-","GO:0005925;GO:0008104","-","KOG1930-Focal adhesion protein Tensin, contains PTB domain[TZ]"]
["RND3",95.744186,22.791018,-2.070719517,0,0,"down","RND3","-","GO:0000166;GO:0003924;GO:0005525;GO:0005622;GO:0007264","-","KOG0393-Ras-related small GTPase, Rho type[R]"]
["FAM107B",59.763771,14.218341,-2.071518042,0,0,"down","FAM107B","-","GO:0007605","-","-"]
["GALNT6",58.962765,13.964923,-2.077996561,0,0,"down","GALNT6","polypeptide N-acetylgalactosaminyltransferase 6","GO:0000139;GO:0004653;GO:0005794;GO:0006486;GO:0016020;GO:0016021;GO:0016740;GO:0016757;GO:0030246;GO:0048471","K00710-ko00512 Mucin type O-glycan biosynthesis","KOG3736-Polypeptide N-acetylgalactosaminyltransferase[O]"]
["CENPK",6.294656,1.489224,-2.079566766,{"v":9.75e-19,"d":"9.75E-19"},{"v":2.75e-18,"d":"2.75E-18"},"down","CENPK","centromere protein K","GO:0000775;GO:0000776;GO:0000777;GO:0005634;GO:0005694;GO:0051382","-","-"]
["PRRX2",27.01375,6.37135,-2.084022929,{"v":1.89e-195,"d":"1.89E-195"},{"v":2.02e-194,"d":"2.02E-194"},"down","PRRX2","paired related homeobox 2","GO:0003677;GO:0005634;GO:0006355;GO:0007275;GO:0043565;GO:0003677;GO:0005634;GO:0006355;GO:0007275;GO:0043565","-","KOG0484-Transcription factor PHOX2/ARIX, contains HOX domain[K]"]
["PPP1R13B",88.764526,20.924408,-2.084796425,0,0,"down","PPP1R13B","-","GO:0005634;GO:0005654;GO:0005829;GO:0005886;GO:0006915;GO:0008134;GO:0045786;GO:0072332","-","KOG0515-p53-interacting protein 53BP/ASPP, contains ankyrin and SH3 domains[D]"]
["RAMP3",8.590433,2.024464,-2.085190864,{"v":5.22e-48,"d":"5.22E-48"},{"v":2.31e-47,"d":"2.31E-47"},"down","RAMP3","receptor activity modifying protein 3","GO:0001605;GO:0001921;GO:0005622;GO:0005764;GO:0005886;GO:0006816;GO:0006886;GO:0007186;GO:0007189;GO:0008277;GO:0008565;GO:0009986;GO:0010628;GO:0010739;GO:0010942;GO:0015026;GO:0015031;GO:0016020;GO:0016021;GO:0031623;GO:0033138;GO:0038041;GO:0043235;GO:0051897;GO:0070374;GO:0071392;GO:0072659;GO:0086103;GO:0097643;GO:0097647;GO:0150058;GO:1903078;GO:1903143;GO:1905665;GO:1990410","K08449-ko04270 Vascular smooth muscle contraction","-"]
["LOC107054065",14.081583,3.318314,-2.085287211,{"v":1.83e-77,"d":"1.83E-77"},{"v":1.04e-76,"d":"1.04E-76"},"down","LOC107054065","-","-","-","-"]
["LAMC2",14.759175,3.473067,-2.087329933,{"v":4.99e-179,"d":"4.99E-179"},{"v":5.03e-178,"d":"5.03E-178"},"down","LAMC2","-","-","K06246-ko04151 PI3K-Akt signaling pathway;ko04512 ECM-receptor interaction;ko04510 Focal adhesion;ko05200 Pathways in cancer;ko05222 Small cell lung cancer;ko05146 Amoebiasis;ko05145 Toxoplasmosis","-"]
["PPP2R2B",72.264404,16.993368,-2.088313364,0,0,"down","PPP2R2B","-","GO:0000159;GO:0000278;GO:0004722;GO:0005829;GO:0019888;GO:0032502;GO:0043666;GO:0070262","K04354-ko03015 mRNA surveillance pathway;ko04390 Hippo signaling pathway;ko04391 Hippo signaling pathway -fly;ko04071 Sphingolipid signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04152 AMPK signaling pathway;ko04111 Cell cycle - yeast;ko04530 Tight junction;ko04261 Adrenergic signaling in cardiomyocytes;ko04728 Dopaminergic synapse;ko05160 Hepatitis C;ko05142 Chagas disease (American trypanosomiasis)","KOG1354-Serine/threonine protein phosphatase 2A, regulatory subunit[T]"]
["FAM89A",81.723671,19.211128,-2.08881178,0,0,"down","FAM89A","-","-","-","-"]
["SEPT8",130.549561,30.59737,-2.09311805,0,0,"down","SEPT8","septin 8","GO:0000166;GO:0005525","-","KOG3859-Septins (P-loop GTPases)[D]"]
["ZNF185L",127.317192,29.798353,-2.095122746,0,0,"down","ZNF185L","-","-","-","-"]
["SNX9",117.090492,27.299009,-2.100703446,0,0,"down","SNX9","-","GO:0000278;GO:0000281;GO:0005545;GO:0005737;GO:0005802;GO:0005829;GO:0005886;GO:0006886;GO:0006897;GO:0006898;GO:0015031;GO:0016020;GO:0016197;GO:0030136;GO:0030659;GO:0031234;GO:0031410;GO:0031625;GO:0032461;GO:0035091;GO:0036089;GO:0042802;GO:0042803;GO:0043547;GO:0045860;GO:0051044;GO:0060988;GO:0071933;GO:0097320","-","KOG2528-Sorting nexin SNX9/SH3PX1 and related proteins[U]"]
["STMN3",6.422973,1.496771,-2.10138772,{"v":1.69e-51,"d":"1.69E-51"},{"v":7.7e-51,"d":"7.70E-51"},"down","STMN3","stathmin 3","GO:0005737;GO:0007019;GO:0015631;GO:0019904;GO:0031110;GO:0031122;GO:0031175;GO:0035021;GO:0043005;GO:0043087;GO:0051493","-","-"]
["TIAM1",38.00753,8.849077,-2.102686383,0,0,"down","TIAM1","-","GO:0005085;GO:0005089;GO:0005622;GO:0005829;GO:0005886;GO:0005911;GO:0007160;GO:0007165;GO:0008284;GO:0010717;GO:0016477;GO:0016601;GO:0019900;GO:0030335;GO:0030676;GO:0031234;GO:0032092;GO:0035023;GO:0035556;GO:0044291;GO:0090630","K05731-ko04014 Ras signaling pathway;ko04015 Rap1 signaling pathway;ko04024 cAMP signaling pathway;ko04810 Regulation of actin cytoskeleton;ko04062 Chemokine signaling pathway;ko05205 Proteoglycans in cancer","KOG3519-Invasion-inducing protein TIAM1/CDC24 and related RhoGEF GTPases[T]"]
["FAM83C",34.707153,8.080108,-2.102786545,{"v":2.78e-216,"d":"2.78E-216"},{"v":3.27e-215,"d":"3.27E-215"},"down","FAM83C","-","GO:0019901","-","-"]
["GNG2",22.825327,5.313558,-2.102885399,{"v":4.76e-133,"d":"4.76E-133"},{"v":3.89e-132,"d":"3.89E-132"},"down","GNG2","G protein subunit gamma 2","GO:0003924;GO:0005834;GO:0005886;GO:0007165;GO:0007186;GO:0008283;GO:0016020;GO:0031681","K07826-ko04014 Ras signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04062 Chemokine signaling pathway;ko04724 Glutamatergic synapse;ko04727 GABAergic synapse;ko04725 Cholinergic synapse;ko04728 Dopaminergic synapse;ko04726 Serotonergic synapse;ko04723 Retrograde endocannabinoid signaling;ko04713 Circadian entrainment;ko05200 Pathways in cancer;ko05032 Morphine addiction;ko05034 Alcoholism","KOG4119-G protein gamma subunit[T]"]
["PTDSS2",166.11525,38.627064,-2.104500595,0,0,"down","PTDSS2","phosphatidylserine synthase 2","GO:0003882;GO:0005622;GO:0005789;GO:0006659;GO:0016020;GO:0016021","K08730-ko00564 Glycerophospholipid metabolism","KOG2735-Phosphatidylserine synthase[I]"]
["IL13RA1",58.591305,13.612433,-2.105761635,0,0,"down","IL13RA1","-","GO:0004896;GO:0016020;GO:0016021;GO:0019221","K05076-ko04630 Jak-STAT signaling pathway;ko04060 Cytokine-cytokine receptor interaction","-"]
["LMBR1",85.155014,19.693684,-2.112358465,0,0,"down","LMBR1","limb development membrane protein 1","GO:0016020;GO:0016021;GO:0042733","-","KOG3722-Lipocalin-interacting membrane receptor (LIMR)[V]"]
["KIF11",5.11207,1.181981,-2.112700747,{"v":6.46e-50,"d":"6.46E-50"},{"v":2.91e-49,"d":"2.91E-49"},"down","KIF11","kinesin family member 11","GO:0000166;GO:0000922;GO:0003774;GO:0003777;GO:0005524;GO:0005819;GO:0005829;GO:0005874;GO:0005876;GO:0007018;GO:0007051;GO:0007100;GO:0008017;GO:0019901;GO:0044877;GO:0046602;GO:0051225;GO:0072686;GO:0090307","-","KOG0243-Kinesin-like protein[Z]"]
["PCYOX1L",21.594164,4.963023,-2.121350419,0,0,"down","PCYOX1L","-","GO:0001735;GO:0016491;GO:0016670;GO:0030328;GO:0055114","-","-"]
["MMD",208.716202,47.886425,-2.123853958,0,0,"down","MMD","monocyte to macrophage differentiation associated","GO:0016020;GO:0016021;GO:0004672;GO:0005794;GO:0006468;GO:0016020;GO:0016021;GO:0019835;GO:0032880;GO:0045666;GO:0045860","-","KOG4243-Macrophage maturation-associated protein[V]"]
["APCDD1",23.186573,5.319195,-2.124009772,0,0,"down","APCDD1","APC down-regulated 1","GO:0005886;GO:0005887;GO:0016020;GO:0016021;GO:0016055;GO:0017147;GO:0030178;GO:0042802;GO:0043615","-","-"]
["IRX6",31.680626,7.266847,-2.124199406,{"v":1.71e-188,"d":"1.71E-188"},{"v":1.79e-187,"d":"1.79E-187"},"down","IRX6","-","-","-","KOG0773-Transcription factor MEIS1 and related HOX domain proteins[K]"]
["CDH1",239.262772,54.723042,-2.128375603,0,0,"down","CDH1","cadherin 1","GO:0005509;GO:0005515;GO:0005802;GO:0005886;GO:0005913;GO:0007155;GO:0007156;GO:0008013;GO:0009898;GO:0015629;GO:0016020;GO:0016021;GO:0016328;GO:0016342;GO:0016600;GO:0022408;GO:0030027;GO:0030054;GO:0030336;GO:0030506;GO:0030864;GO:0032794;GO:0034332;GO:0042307;GO:0042802;GO:0043296;GO:0045295;GO:0045893;GO:0046872;GO:0048471;GO:0050839;GO:0071285;GO:0071681;GO:0072659;GO:0098609","K05689-ko04015 Rap1 signaling pathway;ko04390 Hippo signaling pathway;ko04514 Cell adhesion molecules (CAMs);ko04520 Adherens junction;ko05200 Pathways in cancer;ko05216 Thyroid cancer;ko05218 Melanoma;ko05219 Bladder cancer;ko05213 Endometrial cancer;ko05130 Pathogenic Escherichia coli infection;ko05100 Bacterial invasion of epithelial cells","KOG4289-Cadherin EGF LAG seven-pass G-type receptor[T]"]
["ARID3A",35.205593,8.027577,-2.13276814,0,0,"down","ARID3A","-","GO:0000977;GO:0001228;GO:0003677;GO:0003682;GO:0003700;GO:0005634;GO:0005654;GO:0005829;GO:0006355;GO:0006366;GO:0042803;GO:0043231;GO:0045121;GO:0045944","-","KOG2744-DNA-binding proteins Bright/BRCAA1/RBP1 and related proteins containing BRIGHT domain[K]"]
["ANKRD9",82.439636,18.78513,-2.133747035,{"v":1.48e-293,"d":"1.48E-293"},{"v":2.21e-292,"d":"2.21E-292"},"down","ANKRD9","-","-","-","-"]
["LRR1",16.145761,3.672563,-2.136296297,{"v":2.46e-106,"d":"2.46E-106"},{"v":1.71e-105,"d":"1.71E-105"},"down","LRR1","-","GO:0005225;GO:0005737;GO:0005886;GO:0007165;GO:0015698;GO:0034702;GO:0098656","-","KOG0472-Leucine-rich repeat protein[S]"]
["LYPD6B",51.490868,11.708738,-2.136731004,{"v":7.3e-276,"d":"7.30E-276"},{"v":1.03e-274,"d":"1.03E-274"},"down","LYPD6B","-","GO:0030548;GO:0099601","-","-"]
["FAM46B",55.903286,12.705564,-2.137472669,{"v":1.39e-275,"d":"1.39E-275"},{"v":1.95e-274,"d":"1.95E-274"},"down","FAM46B","-","-","-","-"]
["PPP1R12B",256.309509,58.233105,-2.137975552,0,0,"down","PPP1R12B","protein phosphatase 1 regulatory subunit 12B","GO:0019901","K12329-ko04810 Regulation of actin cytoskeleton;ko04510 Focal adhesion;ko04921 Oxytocin signaling pathway;ko04270 Vascular smooth muscle contraction;ko05205 Proteoglycans in cancer","KOG0505-Myosin phosphatase, regulatory subunit[OT]"]
["TBC1D9",35.269146,8.010469,-2.138448025,0,0,"down","TBC1D9","-","GO:0005096;GO:0005509;GO:0005622;GO:0006886;GO:0012505;GO:0017137;GO:0031338;GO:0090630","-","KOG4347-GTPase-activating protein VRP[R]"]
["CAPN13",15.473163,3.499133,-2.144698734,{"v":2.26e-95,"d":"2.26E-95"},{"v":1.47e-94,"d":"1.47E-94"},"down","CAPN13","-","GO:0004198;GO:0005509;GO:0005622;GO:0005737;GO:0006508;GO:0008233;GO:0008234;GO:0016787","-","KOG0045-Cytosolic Ca2+-dependent cysteine protease (calpain), large subunit (EF-Hand protein superfamily)[OT]"]
["LOC112531303",11.62168,2.606712,-2.156515534,{"v":1.24e-75,"d":"1.24E-75"},{"v":6.98e-75,"d":"6.98E-75"},"down","LOC112531303","-","-","-","-"]
["CES1L1",197.658844,44.308773,-2.157348227,0,0,"down","CES1L1","-","-","K01044-ko00983 Drug metabolism - other enzymes","-"]
["ENTPD8",56.59877,12.667985,-2.159583637,0,0,"down","ENTPD8","ectonucleoside triphosphate diphosphohydrolase 8","GO:0000166;GO:0005524;GO:0005886;GO:0016020;GO:0016021;GO:0016787;GO:0046872;GO:0102485;GO:0102486;GO:0102487;GO:0102488;GO:0102489;GO:0102490;GO:0102491","K01510-ko00230 Purine metabolism;ko00240 Pyrimidine metabolism;ko05169 Epstein-Barr virus infection","KOG1386-Nucleoside phosphatase[F]"]
["MEIS1",139.536713,31.212364,-2.160455219,0,0,"down","MEIS1","Meis homeobox 1","GO:0000978;GO:0001525;GO:0002089;GO:0003677;GO:0003682;GO:0005634;GO:0005667;GO:0006355;GO:0006366;GO:0007626;GO:0030097;GO:0035855;GO:0043565;GO:0045638;GO:0045665;GO:0045944;GO:0046982;GO:0048514;GO:0060216","-","KOG0773-Transcription factor MEIS1 and related HOX domain proteins[K]"]
["LOC112530337",271.347504,60.613094,-2.162440246,0,0,"down","LOC112530337","-","-","-","-"]
["LSS",33.323326,7.422853,-2.1664867,{"v":5.82e-267,"d":"5.82E-267"},{"v":8.01e-266,"d":"8.01E-266"},"down","LSS","lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)","GO:0000250;GO:0005811;GO:0006694;GO:0006695;GO:0016853;GO:0016866;GO:0031647","K01852-ko00100 Steroid biosynthesis","KOG0497-Oxidosqualene-lanosterol cyclase and related proteins[I]"]
["ACTG1",191.624527,42.499329,-2.172770262,0,0,"down","ACTG1","Actin, gamma 1","GO:0000166;GO:0005524;GO:0000166;GO:0005524;GO:0005737;GO:0005856;GO:0005886;GO:0005925;GO:0097433","K05692-ko04015 Rap1 signaling pathway;ko04390 Hippo signaling pathway;ko04391 Hippo signaling pathway -fly;ko04145 Phagosome;ko04810 Regulation of actin cytoskeleton;ko04210 Apoptosis;ko04510 Focal adhesion;ko04520 Adherens junction;ko04530 Tight junction;ko04611 Platelet activation;ko04670 Leukocyte transendothelial migration;ko04921 Oxytocin signaling pathway;ko04919 Thyroid hormone signaling pathway;ko04745 Phototransduction - fly;ko05205 Proteoglycans in cancer;ko05410 Hypertrophic cardiomyopathy (HCM);ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC);ko05414 Dilated cardiomyopathy (DCM);ko05416 Viral myocarditis;ko05110 Vibrio cholerae infection;ko05130 Pathogenic Escherichia coli infection;ko05132 Salmonella infection;ko05131 Shigellosis;ko05100 Bacterial invasion of epithelial cells;ko05164 Influenza A","KOG0676-Actin and related proteins[Z]"]
["RAPGEFL1",15.133328,3.343226,-2.1784165,{"v":3.84e-89,"d":"3.84E-89"},{"v":2.4e-88,"d":"2.40E-88"},"down","RAPGEFL1","-","GO:0005085;GO:0005622;GO:0007264","-","KOG2378-cAMP-regulated guanine nucleotide exchange factor[T]"]
["ESRP2",147.423737,32.43993,-2.184126223,0,0,"down","ESRP2","epithelial splicing regulatory protein 2","GO:0000380;GO:0003676;GO:0003723;GO:0003729;GO:0005634;GO:0005654;GO:0043484;GO:0050679;GO:0060441;GO:0060445;GO:0003676;GO:0003723;GO:0003729;GO:0005634;GO:0006397;GO:0008380;GO:0043484","-","KOG1365-RNA-binding protein Fusilli, contains RRM domain[AR]"]
["HIVEP3",5.155732,1.130445,-2.189286471,{"v":2.74e-169,"d":"2.74E-169"},{"v":2.66e-168,"d":"2.66E-168"},"down","HIVEP3","-","GO:0003676;GO:0003677;GO:0003700;GO:0005634;GO:0006366;GO:0007165;GO:0007275;GO:0008270;GO:0035914;GO:0043565;GO:0044212;GO:0045893;GO:0046872","-","KOG1074-Transcriptional repressor SALM[K]"]
["RAB11FIP4",13.710198,3.002229,-2.191143476,0,0,"down","RAB11FIP4","-","GO:0003407;GO:0005509;GO:0005768;GO:0017137;GO:0030139;GO:0030306;GO:0030496;GO:0032154;GO:0032465;GO:0042803;GO:0048471;GO:0055038;GO:1903452","K12485-ko04144 Endocytosis","KOG0982-Centrosomal protein Nuf[DZ]"]
["SLC29A3",14.935227,3.269032,-2.191783761,{"v":1.83e-100,"d":"1.83E-100"},{"v":1.23e-99,"d":"1.23E-99"},"down","SLC29A3","-","-","-","KOG1479-Nucleoside transporter[F]"]
["HR",30.041414,6.567512,-2.193533883,0,0,"down","HR","-","-","-","-"]
["PDLIM7",114.127396,24.918596,-2.195350459,0,0,"down","PDLIM7","PDZ and LIM domain 7","GO:0001725;GO:0005737;GO:0005884;GO:0006913;GO:0008134;GO:0015629;GO:0030864;GO:0031941;GO:0032880;GO:0033613;GO:0043433;GO:0046872;GO:0048471;GO:0001503;GO:0001725;GO:0005515;GO:0005737;GO:0005856;GO:0005884;GO:0006913;GO:0007275;GO:0008134;GO:0015629;GO:0030018;GO:0030154;GO:0030864;GO:0031941;GO:0032880;GO:0033613;GO:0043433;GO:0046872;GO:0048471","-","KOG1703-Adaptor protein Enigma and related PDZ-LIM proteins[TZ]"]
["RGS5",1068.680908,233.07666,-2.196954703,0,0,"down","RGS5","-","GO:0005096;GO:0005737;GO:0005829;GO:0005886;GO:0043547","-","KOG3589-G protein signaling regulators[T]"]
["FEV",34.846107,7.598763,-2.197161001,{"v":5.51e-114,"d":"5.51E-114"},{"v":4.04e-113,"d":"4.04E-113"},"down","FEV","-","GO:0000981;GO:0003677;GO:0003700;GO:0005634;GO:0006355;GO:0006357;GO:0030154;GO:0043565","-","KOG3806-Predicted transcription factor[K]"]
["ACTN1",233.563583,50.792751,-2.201120829,0,0,"down","ACTN1","actinin, alpha 1","GO:0001725;GO:0001726;GO:0003725;GO:0003779;GO:0005178;GO:0005509;GO:0005515;GO:0005622;GO:0005623;GO:0005737;GO:0005856;GO:0005884;GO:0005886;GO:0005903;GO:0005911;GO:0005915;GO:0005916;GO:0005923;GO:0005925;GO:0007015;GO:0016020;GO:0016328;GO:0017166;GO:0030017;GO:0030018;GO:0030027;GO:0030054;GO:0030220;GO:0030274;GO:0030374;GO:0030486;GO:0031252;GO:0036344;GO:0042383;GO:0042803;GO:0042995;GO:0044325;GO:0045214;GO:0046872;GO:0048041;GO:0048741;GO:0051015;GO:0051017;GO:0051219;GO:0051271;GO:0051393;GO:0051639;GO:0051764;GO:0090636;GO:0090637;GO:0097433;GO:0098978;GO:0099173;GO:0099186;GO:1903508;GO:1990357","K05699-ko04810 Regulation of actin cytoskeleton;ko04510 Focal adhesion;ko04520 Adherens junction;ko04530 Tight junction;ko04670 Leukocyte transendothelial migration;ko05203 Viral carcinogenesis;ko05322 Systemic lupus erythematosus;ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC);ko05146 Amoebiasis","KOG0035-Ca2+-binding actin-bundling protein (actinin), alpha chain (EF-Hand protein superfamily)[Z]"]
["CSRP2",137.936142,29.933611,-2.204162289,{"v":3.74e-296,"d":"3.74E-296"},{"v":5.63e-295,"d":"5.63E-295"},"down","CSRP2","cysteine and glycine rich protein 2","GO:0005634;GO:0007275;GO:0030154;GO:0046872","-","KOG1700-Regulatory protein MLP and related LIM proteins[TZ]"]
["PHLDA3",13.066593,2.835475,-2.204220679,{"v":4.57e-42,"d":"4.57E-42"},{"v":1.89e-41,"d":"1.89E-41"},"down","PHLDA3","-","-","-","-"]
["RAB42",14.73063,3.185866,-2.209061641,{"v":1.27e-169,"d":"1.27E-169"},{"v":1.23e-168,"d":"1.23E-168"},"down","RAB42","-","GO:0003924;GO:0005525;GO:0005794","-","-"]
["CKMT1A",5.871677,1.269084,-2.209985044,{"v":7.49e-24,"d":"7.49E-24"},{"v":2.34e-23,"d":"2.34E-23"},"down","CKMT1A","creatine kinase, mitochondrial 1A","GO:0000166;GO:0003824;GO:0005524;GO:0005739;GO:0016301;GO:0016310;GO:0016740;GO:0016772;GO:0032091;GO:0043066;GO:0043209","K00933-ko00330 Arginine and proline metabolism","KOG3581-Creatine kinases[C]"]
["SAMD12",33.293617,7.191405,-2.210900047,0,0,"down","SAMD12","-","-","-","KOG1170-Diacylglycerol kinase[I]"]
["IPMK",54.76292,11.803645,-2.213966937,0,0,"down","IPMK","-","GO:0005634;GO:0005654;GO:0005730;GO:0016301;GO:0016310;GO:0016740;GO:0032958","K00915-ko00562 Inositol phosphate metabolism;ko04070 Phosphatidylinositol signaling system","KOG1620-Inositol polyphosphate multikinase, component of the ARGR transcription regulatory complex[KIT]"]
["RASSF10",9.910375,2.126073,-2.220748515,{"v":1.41e-43,"d":"1.41E-43"},{"v":5.92e-43,"d":"5.92E-43"},"down","RASSF10","-","GO:0007165;GO:0050769;GO:2000179","-","KOG1574-Predicted cell growth/differentiation regulator, contains RA domain[W]"]
["LOC101751866",9.924451,2.123194,-2.224751099,{"v":1.77e-108,"d":"1.77E-108"},{"v":1.25e-107,"d":"1.25E-107"},"down","LOC101751866","-","-","-","-"]
["LOC101747446",19.697161,4.207699,-2.226884296,{"v":1.01e-128,"d":"1.01E-128"},{"v":8.04e-128,"d":"8.04E-128"},"down","LOC101747446","-","-","-","-"]
["LURAP1",72.834671,15.542535,-2.228403543,0,0,"down","LURAP1","-","GO:0001819;GO:0005737;GO:0043123;GO:0043231","-","-"]
["RIOK3",63.18124,13.450557,-2.231830334,0,0,"down","RIOK3","-","GO:0000166;GO:0004674;GO:0005524;GO:0006468;GO:0016301;GO:0016310;GO:0016740;GO:0030490;GO:0030688;GO:0032463;GO:0032728;GO:0039534;GO:0043124;GO:0045089;GO:0046872;GO:0071359;GO:0089720;GO:0098586;GO:1990786","-","KOG2269-Serine/threonine protein kinase[T]"]
["WWOX",34.724056,7.390219,-2.232246451,{"v":2.3e-203,"d":"2.30E-203"},{"v":2.57e-202,"d":"2.57E-202"},"down","WWOX","WW domain containing oxidoreductase","GO:0001649;GO:0003713;GO:0005634;GO:0005737;GO:0005739;GO:0005794;GO:0005829;GO:0005886;GO:0005902;GO:0019899;GO:0030178;GO:0045944;GO:0048705;GO:0071560;GO:0072332;GO:0090575;GO:0097191;GO:2001238;GO:2001241;GO:0005634;GO:0005737;GO:0006915;GO:0016055;GO:0016491;GO:0055114","-","KOG1208-Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)[Q]"]
["HHLA2",97.530907,20.743195,-2.233221349,0,0,"down","HHLA2","-","-","-","KOG3513-Neural cell adhesion molecule L1[T]"]
["TRAF1",11.893177,2.524444,-2.236096571,{"v":4.63e-130,"d":"4.63E-130"},{"v":3.72e-129,"d":"3.72E-129"},"down","TRAF1","-","GO:0005164;GO:0007165;GO:0008270;GO:0031625;GO:0031996;GO:0042802;GO:0042981;GO:0046872;GO:0051092;GO:2001236","K03172-ko04064 NF-kappa B signaling pathway;ko04668 TNF signaling pathway;ko04210 Apoptosis;ko05200 Pathways in cancer;ko05202 Transcriptional misregulation in cancers;ko05203 Viral carcinogenesis;ko05222 Small cell lung cancer;ko05168 Herpes simplex infection;ko05169 Epstein-Barr virus infection","KOG0297-TNF receptor-associated factor[T]"]
["LOC107049257",5.518351,1.16051,-2.249478269,{"v":7.18e-22,"d":"7.18E-22"},{"v":2.16e-21,"d":"2.16E-21"},"down","LOC107049257","-","-","-","-"]
["NTF3",5.854909,1.230976,-2.249844114,{"v":1.46e-16,"d":"1.46E-16"},{"v":3.91e-16,"d":"3.91E-16"},"down","NTF3","neurotrophin 3","GO:0000187;GO:0002092;GO:0005102;GO:0005165;GO:0005166;GO:0005576;GO:0007169;GO:0007267;GO:0008083;GO:0008284;GO:0010469;GO:0016020;GO:0016021;GO:0030335;GO:0031410;GO:0032148;GO:0033138;GO:0042056;GO:0042981;GO:0043524;GO:0045664;GO:0048812;GO:0050731;GO:0050732;GO:0050918;GO:0050930;GO:0090630;GO:2000251","K04356-ko04010 MAPK signaling pathway;ko04722 Neurotrophin signaling pathway","-"]
["TMEM184A",34.250031,7.178568,-2.254337309,0,0,"down","TMEM184A","-","GO:0005215;GO:0016020;GO:0016021;GO:0031901","-","KOG2641-Predicted seven transmembrane receptor - rhodopsin family[T]"]
["ARHGEF26",61.676449,12.916277,-2.255529419,0,0,"down","ARHGEF26","-","GO:0001886;GO:0005089;GO:0035023;GO:0097178","-","KOG3523-Putative guanine nucleotide exchange factor TIM[T]"]
["LOC112533524",26.12649,5.468723,-2.256237423,{"v":1.83e-11,"d":"1.83E-11"},{"v":4.24e-11,"d":"4.24E-11"},"down","LOC112533524","-","-","-","-"]
["TCF21",41.561073,8.674228,-2.260425632,{"v":4.14e-133,"d":"4.14E-133"},{"v":3.39e-132,"d":"3.39E-132"},"down","TCF21","transcription factor 21","GO:0000122;GO:0001657;GO:0001658;GO:0001763;GO:0001822;GO:0001944;GO:0005634;GO:0006366;GO:0007530;GO:0007548;GO:0009887;GO:0014707;GO:0030855;GO:0032835;GO:0042826;GO:0043425;GO:0045944;GO:0046983;GO:0048286;GO:0048536;GO:0048557;GO:0048608;GO:0048732;GO:0050681;GO:0060008;GO:0060021;GO:0060425;GO:0060426;GO:0060435;GO:0060541;GO:0060766;GO:0070888;GO:0072162;GO:0072277","-","KOG4447-Transcription factor TWIST[K]"]
["MPZL2",130.726929,27.245527,-2.262465057,0,0,"down","MPZL2","myelin protein zero like 2","GO:0016020;GO:0016021;GO:0098609","-","-"]
["NDOR1",24.931948,5.174035,-2.268633891,0,0,"down","NDOR1","-","GO:0003958;GO:0005634;GO:0005737;GO:0005829;GO:0008219;GO:0010181;GO:0016226;GO:0016491;GO:0016651;GO:0036245;GO:0045111;GO:0048471;GO:0050660;GO:0050661;GO:0055114","-","KOG1159-NADP-dependent flavoprotein reductase[C]"]
["LOC107049468",78.274078,16.236151,-2.269324947,{"v":2.28e-172,"d":"2.28E-172"},{"v":2.24e-171,"d":"2.24E-171"},"down","LOC107049468","-","-","-","-"]
["KIRREL3",7.230597,1.494646,-2.27431094,{"v":4.89e-56,"d":"4.89E-56"},{"v":2.34e-55,"d":"2.34E-55"},"down","KIRREL3","-","GO:0001764;GO:0002121;GO:0005576;GO:0005886;GO:0007156;GO:0007416;GO:0016020;GO:0016021;GO:0021740;GO:0021766;GO:0030097;GO:0030424;GO:0030425;GO:0043198;GO:0048812;GO:0072102","-","KOG4222-Axon guidance receptor Dscam[T]"]
["BCHE",147.245239,30.327429,-2.279525883,0,0,"down","BCHE","butyrylcholinesterase","GO:0003990;GO:0004104;GO:0005615;GO:0005641;GO:0005783;GO:0016787;GO:0042802;GO:0052689","-","KOG4389-Acetylcholinesterase/Butyrylcholinesterase[T]"]
["ABTB2",24.475948,5.033061,-2.281856751,0,0,"down","ABTB2","-","-","-","-"]
["PGM5",302.567627,62.197189,-2.282336351,0,0,"down","PGM5","-","GO:0001725;GO:0004614;GO:0005829;GO:0005913;GO:0005914;GO:0005925;GO:0005975;GO:0005978;GO:0006006;GO:0009898;GO:0014704;GO:0016010;GO:0016868;GO:0019388;GO:0030018;GO:0030055;GO:0042383;GO:0043034;GO:0071704","-","KOG0625-Phosphoglucomutase[G]"]
["NEK2",5.965653,1.225783,-2.282976462,{"v":5.29e-28,"d":"5.29E-28"},{"v":1.79e-27,"d":"1.79E-27"},"down","NEK2","NIMA related kinase 2","GO:0000070;GO:0000776;GO:0000794;GO:0000922;GO:0004672;GO:0005524;GO:0005654;GO:0005813;GO:0006468;GO:0007059;GO:0019903;GO:0030496;GO:0032212;GO:0032991;GO:0043392;GO:0046602;GO:0046777;GO:0051299;GO:0051973;GO:0051988;GO:0090307;GO:1903126;GO:1904355","-","KOG0589-Serine/threonine protein kinase[R]"]
["BEND7",147.329926,30.223263,-2.285319172,0,0,"down","BEND7","BEN domain containing 7","-","-","-"]
["TSPAN1",251.62088,51.442524,-2.29021831,0,0,"down","TSPAN1","tetraspanin 1","GO:0005654;GO:0005737;GO:0005886;GO:0005887;GO:0007166;GO:0008283;GO:0016020;GO:0016021;GO:0016477;GO:0030054;GO:0031982;GO:0043231;GO:0045807;GO:0048471;GO:0050821","-","-"]
["RASL11B",57.487911,11.73987,-2.291842174,{"v":6.62e-307,"d":"6.62E-307"},{"v":1.02e-305,"d":"1.02E-305"},"down","RASL11B","-","GO:0000166;GO:0003924;GO:0005160;GO:0005525;GO:0007165;GO:0016020;GO:0030512","-","KOG0395-Ras-related GTPase[R]"]
["SLC17A9",7.345679,1.498174,-2.293690663,{"v":2.77e-65,"d":"2.77E-65"},{"v":1.43e-64,"d":"1.43E-64"},"down","SLC17A9","solute carrier family 17 member 9","GO:0005215;GO:0006820;GO:0016020;GO:0016021;GO:0022857;GO:0055085","-","KOG2532-Permease of the major facilitator superfamily[G]"]
["CPLX1",5.235871,1.065763,-2.2965429,{"v":8.6e-84,"d":"8.60E-84"},{"v":5.17e-83,"d":"5.17E-83"},"down","CPLX1","-","GO:0005326;GO:0006836;GO:0016079;GO:0019905;GO:0030073;GO:0031201;GO:0031630;GO:0098685;GO:0098793;GO:0098794;GO:0098967;GO:0098978;GO:0099003","-","-"]
["NBL1",400.916412,81.024071,-2.306878998,0,0,"down","NBL1","neuroblastoma 1, DAN family BMP antagonist","GO:0005576;GO:0048752;GO:0005576;GO:0005615;GO:0007399;GO:0010469;GO:0016015;GO:0030514;GO:0035582;GO:0036122;GO:0038098;GO:0042803;GO:0045666;GO:0048263;GO:0048812;GO:0090027","K19558-ko04350 TGF-beta signaling pathway","-"]
["PHYHIPL",47.925564,9.676387,-2.308255035,0,0,"down","PHYHIPL","phytanoyl-CoA 2-hydroxylase interacting protein like","GO:0005737","-","-"]
["CITED4",85.013573,17.115614,-2.312380148,0,0,"down","CITED4","Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4","-","-","-"]
["ADM2",28.167229,5.660505,-2.31501497,{"v":2.72e-68,"d":"2.72E-68"},{"v":1.45e-67,"d":"1.45E-67"},"down","ADM2","-","-","-","-"]
["SCIN",311.142487,62.455212,-2.316681533,0,0,"down","SCIN","scinderin","GO:0005509;GO:0005886;GO:0005903;GO:0008285;GO:0042989;GO:0043065;GO:0045654;GO:0051014;GO:0051015;GO:0051127;GO:0051693;GO:0002102;GO:0003779;GO:0005509;GO:0005737;GO:0005856;GO:0030054;GO:0032330;GO:0042995;GO:0046872;GO:0051014;GO:0051015;GO:0051693","K05768-ko04810 Regulation of actin cytoskeleton;ko04666 Fc gamma R-mediated phagocytosis;ko05203 Viral carcinogenesis","KOG0443-Actin regulatory proteins (gelsolin/villin family)[Z]"]
["KRT17",24.272287,4.866136,-2.318461503,{"v":1.6e-106,"d":"1.60E-106"},{"v":1.12e-105,"d":"1.12E-105"},"down","KRT17","keratin 17","GO:0005198;GO:0005882","-","-"]
["GATA6",8.604428,1.721725,-2.32122456,{"v":1.37e-30,"d":"1.37E-30"},{"v":4.84e-30,"d":"4.84E-30"},"down","GATA6","GATA binding protein 6","GO:0000122;GO:0000977;GO:0000978;GO:0000981;GO:0001085;GO:0001103;GO:0001228;GO:0001889;GO:0003148;GO:0003309;GO:0003310;GO:0003677;GO:0003682;GO:0003700;GO:0005634;GO:0005667;GO:0006351;GO:0006355;GO:0006366;GO:0006644;GO:0007493;GO:0008134;GO:0008270;GO:0008584;GO:0010468;GO:0014898;GO:0019901;GO:0030154;GO:0030513;GO:0030855;GO:0031016;GO:0031965;GO:0032911;GO:0032912;GO:0035239;GO:0035987;GO:0042493;GO:0043066;GO:0043565;GO:0043627;GO:0044212;GO:0045766;GO:0045892;GO:0045893;GO:0045944;GO:0046872;GO:0048645;GO:0048738;GO:0051145;GO:0051891;GO:0055007;GO:0060045;GO:0060430;GO:0060486;GO:0060510;GO:0060575;GO:0060947;GO:0070848;GO:0071158;GO:0071371;GO:0071456;GO:0071773;GO:0110024","-","KOG1601-GATA-4/5/6 transcription factors[K]"]
["EPHA4",28.539701,5.686835,-2.327272369,0,0,"down","EPHA4","EPH receptor A4","GO:0000166;GO:0001756;GO:0004672;GO:0004713;GO:0004714;GO:0005003;GO:0005004;GO:0005005;GO:0005524;GO:0005737;GO:0005768;GO:0005769;GO:0005886;GO:0005887;GO:0006468;GO:0007155;GO:0007169;GO:0007275;GO:0007399;GO:0016020;GO:0016021;GO:0016301;GO:0016310;GO:0016740;GO:0018108;GO:0031901;GO:0035282;GO:0043087;GO:0046777;GO:0048013;GO:0097155;GO:0097161;GO:2001108;GO:0000166;GO:0004672;GO:0004713;GO:0005003;GO:0005004;GO:0005005;GO:0005524;GO:0005887;GO:0006468;GO:0007169;GO:0007411;GO:0007628;GO:0008045;GO:0010977;GO:0016020;GO:0016021;GO:0016301;GO:0016310;GO:0016740;GO:0018108;GO:0021957;GO:0030424;GO:0030425;GO:0031901;GO:0042731;GO:0042802;GO:0043087;GO:0043507;GO:0046777;GO:0048013;GO:0048681;GO:0048710;GO:0050770;GO:0050821;GO:0061001;GO:0061098;GO:0072178;GO:0097155;GO:0097156;GO:0097161;GO:0097485;GO:0098685;GO:0098883;GO:0098978;GO:0099055;GO:0099056;GO:0106030;GO:1900272;GO:1902004;GO:1902961;GO:1903051;GO:1904646;GO:1905244;GO:1990782;GO:2001108","-","KOG0196-Tyrosine kinase, EPH (ephrin) receptor family[T]"]
["CTXN1",6.694706,1.329058,-2.332616635,{"v":7.07e-47,"d":"7.07E-47"},{"v":3.09e-46,"d":"3.09E-46"},"down","CTXN1","-","-","-","-"]
["TMSB15B",269.20343,53.050247,-2.343265418,0,0,"down","TMSB15B","thymosin beta 15B","GO:0003785;GO:0007015","-","KOG4794-Thymosin beta[N]"]
["CKB",811.148621,159.277542,-2.348423411,0,0,"down","CKB","creatine kinase B","GO:0000166;GO:0003824;GO:0004111;GO:0005524;GO:0005615;GO:0005737;GO:0005829;GO:0006754;GO:0016301;GO:0016310;GO:0016740;GO:0016772;GO:0031625;GO:0043209;GO:0065010","K00933-ko00330 Arginine and proline metabolism","-"]
["HINTW",1098.11792,215.500519,-2.349269736,0,0,"down","HINTW","histidine triad nucleotide binding protein W","-","-","-"]
["AURKA",7.674414,1.505556,-2.349760223,{"v":5.9e-41,"d":"5.90E-41"},{"v":2.41e-40,"d":"2.41E-40"},"down","AURKA","-","GO:0000166;GO:0000212;GO:0000226;GO:0000278;GO:0000780;GO:0004672;GO:0004674;GO:0004712;GO:0005524;GO:0005634;GO:0005813;GO:0005815;GO:0005829;GO:0005876;GO:0006468;GO:0007049;GO:0007051;GO:0007052;GO:0007057;GO:0007098;GO:0007100;GO:0009611;GO:0009948;GO:0015630;GO:0019901;GO:0031616;GO:0031625;GO:0031647;GO:0032091;GO:0032133;GO:0032436;GO:0032465;GO:0035174;GO:0035404;GO:0042585;GO:0043066;GO:0043203;GO:0045120;GO:0046982;GO:0048471;GO:0051233;GO:0051321;GO:0051642;GO:0071539;GO:0072686;GO:0072687;GO:0097421;GO:0097431;GO:1900195;GO:1990138","K11481-ko04114 Oocyte meiosis","KOG0580-Serine/threonine protein kinase[D]"]
["LOC107052542",6.348649,1.240973,-2.35497789,{"v":3.17e-30,"d":"3.17E-30"},{"v":1.11e-29,"d":"1.11E-29"},"down","LOC107052542","-","-","-","-"]
["PRELID3A",72.236481,14.113667,-2.355634737,0,0,"down","PRELID3A","PRELI domain containing 3A","GO:0005758;GO:0015914;GO:1990050","-","KOG3336-Predicted member of the intramitochondrial sorting protein family[U]"]
["DHCR24",21.659723,4.222269,-2.358924392,{"v":7.21e-236,"d":"7.21E-236"},{"v":9.03e-235,"d":"9.03E-235"},"down","DHCR24","24-dehydrocholesterol reductase","GO:0000246;GO:0005634;GO:0005783;GO:0006695;GO:0006979;GO:0008104;GO:0008203;GO:0009888;GO:0016020;GO:0016021;GO:0016125;GO:0016491;GO:0016628;GO:0019899;GO:0030539;GO:0031639;GO:0042605;GO:0042987;GO:0043066;GO:0043154;GO:0043588;GO:0050660;GO:0055114;GO:0061024;GO:0071949","K09828-ko00100 Steroid biosynthesis","KOG1262-FAD-binding protein DIMINUTO[R]"]
["KIF2C",5.260913,1.014353,-2.374753387,{"v":2.06e-39,"d":"2.06E-39"},{"v":8.24e-39,"d":"8.24E-39"},"down","KIF2C","-","GO:0000166;GO:0000775;GO:0003774;GO:0003777;GO:0005524;GO:0005871;GO:0005874;GO:0007018;GO:0008017;GO:0016887","-","KOG0246-Kinesin-like protein[Z]"]
["CHRNA3",12.955162,2.495009,-2.376410131,{"v":2.01e-57,"d":"2.01E-57"},{"v":9.78e-57,"d":"9.78E-57"},"down","CHRNA3","cholinergic receptor nicotinic alpha 3 subunit","GO:0004888;GO:0005216;GO:0005230;GO:0005515;GO:0005886;GO:0005892;GO:0006811;GO:0007165;GO:0007210;GO:0007399;GO:0015464;GO:0016020;GO:0016021;GO:0022848;GO:0022850;GO:0030054;GO:0034220;GO:0035095;GO:0045202;GO:0045211;GO:0060078;GO:0060079;GO:0060084","K04805-ko04080 Neuroactive ligand-receptor interaction;ko04725 Cholinergic synapse","KOG3645-Acetylcholine receptor[T]"]
["LOC415787",41.848351,8.03046,-2.38161624,{"v":8.61e-279,"d":"8.61E-279"},{"v":1.23e-277,"d":"1.23E-277"},"down","LOC415787","-","GO:0016787","K03927-ko00983 Drug metabolism - other enzymes","-"]
["SPINT1",178.596176,34.239697,-2.382959351,0,0,"down","SPINT1","-","GO:0001843;GO:0004867;GO:0005886;GO:0010951;GO:0016020;GO:0016021;GO:0030198","-","-"]
["DUOXA2",20.166176,3.786218,-2.413108155,{"v":5.53e-128,"d":"5.53E-128"},{"v":4.38e-127,"d":"4.38E-127"},"down","DUOXA2","-","GO:0005789;GO:0015031;GO:0016020;GO:0016021","-","-"]
["FGFBP1",305.206299,57.261974,-2.414135427,0,0,"down","FGFBP1","-","GO:0090050;GO:1903589","-","-"]
["BIRC5",31.407999,5.886495,-2.415651262,{"v":5.9e-79,"d":"5.90E-79"},{"v":3.4e-78,"d":"3.40E-78"},"down","BIRC5","baculoviral IAP repeat containing 5","GO:0000226;GO:0004842;GO:0004869;GO:0005634;GO:0005737;GO:0007346;GO:0009966;GO:0016567;GO:0043066;GO:0043524;GO:0061178;GO:0061469;GO:0090307;GO:1990001","K08731-ko04390 Hippo signaling pathway;ko04210 Apoptosis;ko04215 Apoptosis - multiple species;ko05200 Pathways in cancer;ko05210 Colorectal cancer;ko05161 Hepatitis B;ko01524 Platinum drug resistance","KOG1101-Apoptosis inhibitor IAP1 and related BIR domain proteins[DR]"]
["MCM3",9.903505,1.846278,-2.423319407,{"v":2.5e-101,"d":"2.50E-101"},{"v":1.69e-100,"d":"1.69E-100"},"down","MCM3","minichromosome maintenance complex component 3","GO:0000166;GO:0003677;GO:0003682;GO:0004386;GO:0005524;GO:0005634;GO:0005654;GO:0005737;GO:0005813;GO:0006260;GO:0006270;GO:0016787;GO:0042555;GO:0048471;GO:0000166;GO:0003677;GO:0003682;GO:0004386;GO:0005524;GO:0005634;GO:0006260;GO:0006270;GO:0007049;GO:0016787;GO:0042555","K02541-ko03030 DNA replication;ko04110 Cell cycle;ko04111 Cell cycle - yeast;ko04113 Meiosis - yeast","KOG0479-DNA replication licensing factor, MCM3 component[L]"]
["LOC107052410",93.071892,17.347767,-2.423595564,{"v":5.99e-31,"d":"5.99E-31"},{"v":2.12e-30,"d":"2.12E-30"},"down","LOC107052410","-","-","-","-"]
["ACAP3",27.903419,5.194456,-2.425397333,0,0,"down","ACAP3","-","GO:0005096;GO:0043547;GO:0046872","K12489-ko04144 Endocytosis","KOG0521-Putative GTPase activating proteins (GAPs)[T]"]
["CAPNS2",50.184208,9.335136,-2.426490502,{"v":2.88e-205,"d":"2.88E-205"},{"v":3.25e-204,"d":"3.25E-204"},"down","CAPNS2","-","GO:0004198;GO:0005509;GO:0006508","-","-"]
["LOC107053185",8.739474,1.617254,-2.43400017,{"v":1.88e-125,"d":"1.88E-125"},{"v":1.47e-124,"d":"1.47E-124"},"down","LOC107053185","-","-","-","-"]
["PPP1R3G",52.910542,9.788958,-2.434327993,{"v":2.27e-294,"d":"2.27E-294"},{"v":3.4e-293,"d":"3.40E-293"},"down","PPP1R3G","-","-","-","-"]
["OSR1",81.349289,15.017169,-2.437516872,{"v":4.32e-200,"d":"4.32E-200"},{"v":4.75e-199,"d":"4.75E-199"},"down","OSR1","odd-skipped related transciption factor 1","-","-","[KOG3623-Homeobox transcription factor SIP1[K], KOG2462-C2H2-type Zn-finger protein[K]]"]
["XKRX",35.505177,6.536871,-2.441357267,{"v":7.47e-190,"d":"7.47E-190"},{"v":7.85e-189,"d":"7.85E-189"},"down","XKRX","-","GO:0016020;GO:0016021","-","-"]
["OC3",711.721619,130.96109,-2.442174825,0,0,"down","OC3","osteocalcin-like protein OC3","GO:0005509;GO:0005576;GO:0032571;GO:0060348;GO:1900076","-","-"]
["LOC101750739",68.926926,12.678527,-2.442680534,0,0,"down","LOC101750739","poliovirus receptor-related protein 4-like","-","K06593-ko04520 Adherens junction","-"]
["LPAR6",53.565933,9.851871,-2.442846121,{"v":3.15e-231,"d":"3.15E-231"},{"v":3.89e-230,"d":"3.89E-230"},"down","LPAR6","lysophosphatidic acid receptor 6","GO:0004930;GO:0005886;GO:0007165;GO:0007186;GO:0016020;GO:0016021;GO:0043231;GO:0004930;GO:0005886;GO:0005887;GO:0007165;GO:0007186;GO:0016020;GO:0016021;GO:0035025;GO:0051482;GO:0070915","K04273-ko04072 Phospholipase D signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04080 Neuroactive ligand-receptor interaction;ko05200 Pathways in cancer","-"]
["PLK1",7.636359,1.401438,-2.445977008,{"v":6.94e-59,"d":"6.94E-59"},{"v":3.42e-58,"d":"3.42E-58"},"down","PLK1","polo like kinase 1","GO:0000070;GO:0000086;GO:0000122;GO:0000166;GO:0000278;GO:0000281;GO:0000287;GO:0000776;GO:0000780;GO:0000785;GO:0000795;GO:0000922;GO:0000942;GO:0001578;GO:0004672;GO:0004674;GO:0005524;GO:0005634;GO:0005813;GO:0005814;GO:0005819;GO:0005876;GO:0006468;GO:0007094;GO:0007098;GO:0007346;GO:0008017;GO:0010800;GO:0010997;GO:0015630;GO:0016301;GO:0016310;GO:0016321;GO:0016567;GO:0016740;GO:0018105;GO:0019901;GO:0030071;GO:0030496;GO:0031648;GO:0032436;GO:0032465;GO:0033365;GO:0034451;GO:0042802;GO:0043066;GO:0043393;GO:0045143;GO:0045184;GO:0045736;GO:0045862;GO:0051081;GO:0051233;GO:0051443;GO:0070194;GO:0071168;GO:0072425;GO:0090435;GO:1901673;GO:1904668","K06631-ko04068 FoxO signaling pathway;ko04110 Cell cycle;ko04114 Oocyte meiosis;ko04914 Progesterone-mediated oocyte maturation","KOG0575-Polo-like serine/threonine protein kinase[D]"]
["PLCXD1",47.430058,8.703816,-2.446081669,0,0,"down","PLCXD1","phosphatidylinositol specific phospholipase C X domain containing 1","GO:0006629;GO:0008081","-","KOG4306-Glycosylphosphatidylinositol-specific phospholipase C[T]"]
["PLEKHN1",19.513334,3.575074,-2.448415285,{"v":2.34e-160,"d":"2.34E-160"},{"v":2.18e-159,"d":"2.18E-159"},"down","PLEKHN1","-","-","-","KOG2070-Guanine nucleotide exchange factor[F]"]
["LOC112530313",19.549894,3.556161,-2.458768239,{"v":2.17e-14,"d":"2.17E-14"},{"v":5.5e-14,"d":"5.50E-14"},"down","LOC112530313","-","-","-","-"]
["ARHGAP44",17.051104,3.093317,-2.46263856,{"v":3.07e-161,"d":"3.07E-161"},{"v":2.87e-160,"d":"2.87E-160"},"down","ARHGAP44","-","GO:0005096;GO:0005737;GO:0007165;GO:0043547","-","KOG4270-GTPase-activator protein[T]"]
["ESRP1",18.73608,3.384063,-2.468990809,{"v":2.01e-178,"d":"2.01E-178"},{"v":2.03e-177,"d":"2.03E-177"},"down","ESRP1","-","GO:0003676;GO:0003723;GO:0003729;GO:0005634;GO:0005654;GO:0016604;GO:0043484","-","KOG1365-RNA-binding protein Fusilli, contains RRM domain[AR]"]
["PCDH1",58.614613,10.576402,-2.470411464,0,0,"down","PCDH1","protocadherin 1","GO:0005509;GO:0005886;GO:0007155;GO:0007156;GO:0016020;GO:0016021","-","KOG4289-Cadherin EGF LAG seven-pass G-type receptor[T]"]
["AIM1L",58.083035,10.47625,-2.470994447,0,0,"down","AIM1L","-","-","-","-"]
["MAP7D2",52.046978,9.36817,-2.473975238,0,0,"down","MAP7D2","-","GO:0000226;GO:0005198;GO:0015630","-","-"]
["ANLN",17.333178,3.117818,-2.474927574,{"v":1.68e-245,"d":"1.68E-245"},{"v":2.17e-244,"d":"2.17E-244"},"down","ANLN","-","-","-","KOG3640-Actin binding protein Anillin[DZ]"]
["RASD2",23.233601,4.156528,-2.482761941,{"v":7.11e-230,"d":"7.11E-230"},{"v":8.74e-229,"d":"8.74E-229"},"down","RASD2","-","GO:0000166;GO:0001963;GO:0003924;GO:0005525;GO:0007165;GO:0007626;GO:0016020;GO:0031681","-","KOG0395-Ras-related GTPase[R]"]
["LOC427778",27.567348,4.928582,-2.483715951,{"v":1.4e-213,"d":"1.40E-213"},{"v":1.62e-212,"d":"1.62E-212"},"down","LOC427778","-","GO:0016020;GO:0016021;GO:0016787","K01510-ko00230 Purine metabolism;ko00240 Pyrimidine metabolism;ko05169 Epstein-Barr virus infection","-"]
["FAT2",9.763552,1.744504,-2.484589193,0,0,"down","FAT2","-","GO:0005509;GO:0005886;GO:0005913;GO:0007155;GO:0007156;GO:0010631;GO:0016020;GO:0016021;GO:0031589","-","KOG1219-Uncharacterized conserved protein, contains laminin, cadherin and EGF domains[T]"]
["LOC107054259",5.915793,1.056134,-2.48577868,{"v":5.08e-109,"d":"5.08E-109"},{"v":3.61e-108,"d":"3.61E-108"},"down","LOC107054259","-","-","-","-"]
["CCNB3",11.22147,1.988063,-2.496826299,{"v":4.83e-51,"d":"4.83E-51"},{"v":2.2e-50,"d":"2.20E-50"},"down","CCNB3","cyclin B3","GO:0000079;GO:0005634;GO:0007049;GO:0010389;GO:0019901;GO:0051301;GO:0000079;GO:0005634;GO:0010389;GO:0019901","-","KOG0653-Cyclin B and related kinase-activating proteins[D]"]
["IRF6",241.67804,42.5345,-2.506380989,0,0,"down","IRF6","-","GO:0003677;GO:0003700;GO:0005634;GO:0005737;GO:0005829;GO:0006351;GO:0006355;GO:0007050;GO:0008285;GO:0030054;GO:0030216;GO:0043565;GO:0043588;GO:0043616;GO:0044212;GO:0045893;GO:0045944;GO:0048468","-","-"]
["PSD",19.153278,3.362023,-2.510189825,0,0,"down","PSD","-","GO:0005086;GO:0014069;GO:0031175;GO:0032012;GO:0032154;GO:0032587;GO:0043197;GO:0098999;GO:0099092","K12494-ko04144 Endocytosis","-"]
["SUCNR1",13.939447,2.446368,-2.510459983,{"v":1.46e-58,"d":"1.46E-58"},{"v":7.15e-58,"d":"7.15E-58"},"down","SUCNR1","-","-","-","-"]
["COL3A1",2814.425293,493.730774,-2.511043878,0,0,"down","COL3A1","collagen type III alpha 1 chain","GO:0005201;GO:0005576;GO:0005581;GO:0046872","K19720-ko04611 Platelet activation;ko04974 Protein digestion and absorption;ko04933 AGE-RAGE signaling pathway in diabetic complications;ko05146 Amoebiasis","KOG3546-Collagens (type XV)[W]"]
["SLC27A2",17.358524,3.044518,-2.511358533,{"v":3.59e-111,"d":"3.59E-111"},{"v":2.59e-110,"d":"2.59E-110"},"down","SLC27A2","-","GO:0000038;GO:0001676;GO:0003824;GO:0004467;GO:0005783;GO:0006699;GO:0008152;GO:0015245;GO:0015908;GO:0016021;GO:0030176;GO:0031957","K08746-ko04146 Peroxisome;ko03320 PPAR signaling pathway;ko04931 Insulin resistance","-"]
["REEP3",176.889099,30.99608,-2.512687465,0,0,"down","REEP3","receptor accessory protein 3","GO:0006998;GO:0007084;GO:0016020;GO:0016021","-","KOG1726-HVA22/DP1 gene product-related proteins[V]"]
["IFITM1",68.21003,11.944777,-2.513603977,{"v":1.11e-114,"d":"1.11E-114"},{"v":8.21e-114,"d":"8.21E-114"},"down","IFITM1","interferon-induced transmembrane protein 1","GO:0009607;GO:0016020;GO:0016021","-","-"]
["MAB21L3",34.925217,6.104563,-2.516309152,0,0,"down","MAB21L3","-","-","-","KOG3963-Mab-21-like cell fate specification proteins[T]"]
["SQLE",30.896563,5.391093,-2.518796656,{"v":1.08e-246,"d":"1.08E-246"},{"v":1.4e-245,"d":"1.40E-245"},"down","SQLE","squalene epoxidase","GO:0004506;GO:0016020;GO:0016021;GO:0050660;GO:0055114","K00511-ko00100 Steroid biosynthesis;ko00909 Sesquiterpenoid and triterpenoid biosynthesis","KOG1298-Squalene monooxygenase[I]"]
["KCTD7",11.888773,2.06291,-2.526847041,{"v":9.17e-142,"d":"9.17E-142"},{"v":7.82e-141,"d":"7.82E-141"},"down","KCTD7","potassium channel tetramerization domain containing 7","GO:0051260;GO:0005737;GO:0005829;GO:0005886;GO:0016020;GO:0030007;GO:0032411;GO:0051260;GO:0060081;GO:0090461","-","KOG2723-Uncharacterized conserved protein, contains BTB/POZ domain[R]"]
["TUFT1",113.799446,19.723089,-2.528536107,0,0,"down","TUFT1","-","GO:0005737","-","-"]
["JUP",383.307709,66.414894,-2.528924296,0,0,"down","JUP","junction plakoglobin","GO:0001954;GO:0002159;GO:0003713;GO:0005198;GO:0005634;GO:0005737;GO:0005829;GO:0005882;GO:0005886;GO:0005911;GO:0005913;GO:0007155;GO:0014704;GO:0016342;GO:0016477;GO:0019903;GO:0030018;GO:0030057;GO:0032993;GO:0042127;GO:0042307;GO:0043537;GO:0043588;GO:0045294;GO:0045296;GO:0045766;GO:0050839;GO:0050982;GO:0051091;GO:0071665;GO:0071681;GO:0072659;GO:0086073;GO:0086091;GO:0098609;GO:0098911;GO:1903508","-","KOG4224-Armadillo repeat protein VAC8 required for vacuole fusion, inheritance and cytosol-to-vacuole protein targeting[U]"]
["AKR1B10L2",2917.866943,503.007111,-2.536263396,0,0,"down","AKR1B10L2","aldo-keto reductase family 1 member B10-like 2","-","K00011-ko00040 Pentose and glucuronate interconversions;ko00051 Fructose and mannose metabolism;ko00052 Galactose metabolism;ko00561 Glycerolipid metabolism","KOG1577-Aldo/keto reductase family proteins[R]"]
["DCBLD1",57.881992,9.920097,-2.54468844,0,0,"down","DCBLD1","-","GO:0016020;GO:0016021;GO:0070492","-","KOG3516-Neurexin IV[T]"]
["FJX1",42.698357,7.308955,-2.546443501,{"v":1.99e-156,"d":"1.99E-156"},{"v":1.82e-155,"d":"1.82E-155"},"down","FJX1","four jointed box 1","GO:0005615;GO:0010842","-","-"]
["CIART",5.730566,0.973693,-2.557138764,{"v":1.05e-26,"d":"1.05E-26"},{"v":3.45e-26,"d":"3.45E-26"},"down","CIART","-","-","-","-"]
["PDE5A",117.992165,20.007759,-2.560059574,0,0,"down","PDE5A","phosphodiesterase 5A","GO:0004114;GO:0007165;GO:0008081;GO:0016787;GO:0046872","K13762-ko00230 Purine metabolism;ko04022 cGMP - PKG signaling pathway","KOG3689-Cyclic nucleotide phosphodiesterase[T]"]
["MYO3AL",6.862174,1.163394,-2.560325939,{"v":2.42e-130,"d":"2.42E-130"},{"v":1.94e-129,"d":"1.94E-129"},"down","MYO3AL","-","GO:0000166;GO:0003774;GO:0003779;GO:0005524;GO:0016459","-","-"]
["CXADR",86.91777,14.61444,-2.572256612,0,0,"down","CXADR","-","GO:0016020;GO:0016021","-","-"]
["ENTPD2",94.00975,15.773108,-2.575343427,0,0,"down","ENTPD2","ectonucleoside triphosphate diphosphohydrolase 2","GO:0000166;GO:0005524;GO:0016020;GO:0016021;GO:0016787;GO:0016887;GO:0005886;GO:0007186;GO:0009181;GO:0016020;GO:0016021;GO:0016787;GO:0016887;GO:0017110;GO:0017111;GO:0030168","K01509-ko00230 Purine metabolism;ko04742 Taste transduction","KOG1386-Nucleoside phosphatase[F]"]
["P2RY13",13.251017,2.221106,-2.576752938,{"v":1.71e-55,"d":"1.71E-55"},{"v":8.18e-55,"d":"8.18E-55"},"down","P2RY13","-","GO:0004930;GO:0005783;GO:0007165;GO:0007186;GO:0007194;GO:0016020;GO:0016021;GO:0035589;GO:0045028;GO:0071407","K08388-ko04080 Neuroactive ligand-receptor interaction","KOG4219-G protein-coupled receptor[T]"]
["MSMO1",174.019638,29.154757,-2.577446919,0,0,"down","MSMO1","methylsterol monooxygenase 1","GO:0005506;GO:0008610;GO:0016020;GO:0016021;GO:0016491;GO:0055114;GO:0000254;GO:0005506;GO:0005783;GO:0005789;GO:0006629;GO:0006694;GO:0008202;GO:0008610;GO:0016020;GO:0016021;GO:0016126;GO:0016491;GO:0055114","K07750-ko00100 Steroid biosynthesis","KOG0873-C-4 sterol methyl oxidase[I]"]
["LGALS3",483.850922,80.778069,-2.582527047,0,0,"down","LGALS3","galectin 3","GO:0001772;GO:0002548;GO:0005634;GO:0005737;GO:0005743;GO:0019863;GO:0030246;GO:0030593;GO:0030855;GO:0042056;GO:0042129;GO:0043236;GO:0045806;GO:0048245;GO:0048246;GO:0050918;GO:0070232;GO:0071674;GO:0071677;GO:0090280;GO:1902041;GO:2001237","-","KOG3587-Galectin, galactose-binding lectin[W]"]
["TMEM255B",7.759216,1.294852,-2.583123679,{"v":1.25e-41,"d":"1.25E-41"},{"v":5.16e-41,"d":"5.16E-41"},"down","TMEM255B","-","GO:0016020;GO:0016021","-","-"]
["MYL6",2262.028564,376.649658,-2.586322023,0,0,"down","MYL6","-","GO:0000287;GO:0005509;GO:0005515;GO:0005829;GO:0005859;GO:0005903;GO:0008307;GO:0016459;GO:0016460;GO:0016461;GO:0016887;GO:0030239;GO:0030898;GO:0031032;GO:0032036;GO:0042641;GO:0043531;GO:0045159;GO:0046982;GO:0051015;GO:0097513","K12751-ko04921 Oxytocin signaling pathway;ko04270 Vascular smooth muscle contraction","KOG0030-Myosin essential light chain, EF-Hand protein superfamily[Z]"]
["NUSAP1",9.899838,1.647574,-2.587061653,{"v":3.16e-78,"d":"3.16E-78"},{"v":1.82e-77,"d":"1.82E-77"},"down","NUSAP1","nucleolar and spindle associated protein 1","GO:0000070;GO:0000226;GO:0000281;GO:0005730;GO:0005819;GO:0005874;GO:0005876;GO:0007076;GO:0008017;GO:0040001;GO:0045840;GO:0000226;GO:0000281;GO:0003677;GO:0005634;GO:0005737;GO:0005819;GO:0005856;GO:0005874;GO:0007049;GO:0040001;GO:0051301","-","-"]
["ST8SIA5",5.064389,0.842043,-2.58842241,{"v":1.07e-164,"d":"1.07E-164"},{"v":1.02e-163,"d":"1.02E-163"},"down","ST8SIA5","ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5","GO:0003828;GO:0005794;GO:0006486;GO:0008373;GO:0016020;GO:0016021;GO:0016740;GO:0016757;GO:0097503","K03369-ko00604 Glycosphingolipid biosynthesis - ganglio series","KOG2692-Sialyltransferase[G]"]
["AQP9",6.322912,1.042772,-2.600165391,{"v":1.22e-88,"d":"1.22E-88"},{"v":7.56e-88,"d":"7.56E-88"},"down","AQP9","aquaporin 9","GO:0005345;GO:0005350;GO:0006833;GO:0006863;GO:0010033;GO:0015250;GO:0015267;GO:0015791;GO:0015837;GO:0015855;GO:0016020;GO:0016021;GO:0043231;GO:0046689;GO:0055085;GO:0071320;GO:0072531;GO:1904823","-","KOG0224-Aquaporin (major intrinsic protein family)[G]"]
["LOC112531422",255.858902,42.114243,-2.60296829,{"v":7.65e-177,"d":"7.65E-177"},{"v":7.66e-176,"d":"7.66E-176"},"down","LOC112531422","-","-","-","-"]
["SULT1C3",132.772156,21.728689,-2.61127959,0,0,"down","SULT1C3","sulfotransferase family 1C member 3","-","-","KOG1584-Sulfotransferase[R]"]
["HOMER2",34.547493,5.648652,-2.612602495,0,0,"down","HOMER2","-","GO:0003779;GO:0004674;GO:0005524;GO:0005737;GO:0006468;GO:0007605;GO:0008277;GO:0014069;GO:0030160;GO:0032426;GO:0032703;GO:0035256;GO:0035584;GO:0045177;GO:0048148;GO:0048875;GO:0070885;GO:0098978","K15010-ko04068 FoxO signaling pathway;ko04724 Glutamatergic synapse","KOG4590-Signal transduction protein Enabled, contains WH1 domain[T]"]
["LOC101752135",6.586469,1.076124,-2.613660918,{"v":2.6e-40,"d":"2.60E-40"},{"v":1.05e-39,"d":"1.05E-39"},"down","LOC101752135","-","-","-","-"]
["COL7A1",6.844166,1.118159,-2.613749401,{"v":6.86e-212,"d":"6.86E-212"},{"v":7.92e-211,"d":"7.92E-211"},"down","COL7A1","-","-","-","-"]
["LOC112530674",30.087254,4.868818,-2.627508963,0,0,"down","LOC112530674","-","-","-","-"]
["TMC3",5.108432,0.810863,-2.655350445,{"v":2.25e-125,"d":"2.25E-125"},{"v":1.76e-124,"d":"1.76E-124"},"down","TMC3","transmembrane channel like 3","GO:0005887;GO:0016020;GO:0016021","-","-"]
["TAGLN3",7.385728,1.171035,-2.656955936,{"v":2.93e-31,"d":"2.93E-31"},{"v":1.04e-30,"d":"1.04E-30"},"down","TAGLN3","-","GO:0000122;GO:0005634;GO:0043209;GO:0051015","-","KOG2046-Calponin[Z]"]
["GMDS",260.742493,41.258064,-2.659877686,0,0,"down","GMDS","-","-","K01711-ko00051 Fructose and mannose metabolism;ko00520 Amino sugar and nucleotide sugar metabolism","KOG1372-GDP-mannose 4,6 dehydratase[G]"]
["LOC101747455",46.677643,7.311005,-2.67459007,0,0,"down","LOC101747455","-","-","-","-"]
["NUF2",9.958302,1.556514,-2.677581215,{"v":9.08e-62,"d":"9.08E-62"},{"v":4.57e-61,"d":"4.57E-61"},"down","NUF2","NUF2, NDC80 kinetochore complex component","GO:0000775;GO:0000776;GO:0000777;GO:0005515;GO:0005634;GO:0005694;GO:0005737;GO:0005815;GO:0005856;GO:0007049;GO:0031262;GO:0051301;GO:0000776;GO:0005634;GO:0031262","-","KOG4438-Centromere-associated protein NUF2[D]"]
["CACNA1C",12.504564,1.933154,-2.69342628,0,0,"down","CACNA1C","-","GO:0002520;GO:0005216;GO:0005244;GO:0005245;GO:0005262;GO:0005516;GO:0005622;GO:0005737;GO:0005886;GO:0005887;GO:0005891;GO:0006811;GO:0006816;GO:0007204;GO:0007507;GO:0008331;GO:0010881;GO:0014069;GO:0016020;GO:0016021;GO:0030054;GO:0030315;GO:0030425;GO:0034765;GO:0035115;GO:0042383;GO:0042995;GO:0043010;GO:0043204;GO:0045202;GO:0045211;GO:0051393;GO:0055085;GO:0060402;GO:0061337;GO:0061577;GO:0070588;GO:0086002;GO:0086007;GO:0086010;GO:0086012;GO:0086045;GO:0086056;GO:0086091;GO:0098911;GO:0098912;GO:1990454","K04850-ko04010 MAPK signaling pathway;ko04020 Calcium signaling pathway;ko04024 cAMP signaling pathway;ko04022 cGMP - PKG signaling pathway;ko04911 Insulin secretion;ko04912 GnRH signaling pathway;ko04921 Oxytocin signaling pathway;ko04924 Renin secretion;ko04925 Aldosterone synthesis and secretion;ko04260 Cardiac muscle contraction;ko04261 Adrenergic signaling in cardiomyocytes;ko04270 Vascular smooth muscle contraction;ko04724 Glutamatergic synapse;ko04727 GABAergic synapse;ko04725 Cholinergic synapse;ko04728 Dopaminergic synapse;ko04726 Serotonergic synapse;ko04720 Long-term potentiation;ko04723 Retrograde endocannabinoid signaling;ko04742 Taste transduction;ko04713 Circadian entrainment;ko05010 Alzheimer's disease;ko05031 Amphetamine addiction;ko05410 Hypertrophic cardiomyopathy (HCM);ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC);ko05414 Dilated cardiomyopathy (DCM);ko04930 Type II diabetes mellitus","KOG2301-Voltage-gated Ca2+ channels, alpha1 subunits[PT]"]
["LOC107055358",220.55101,34.004604,-2.697310371,0,0,"down","LOC107055358","-","-","-","-"]
["SMTN",115.417557,17.642385,-2.709745188,0,0,"down","SMTN","-","-","-","[KOG0035-Ca2+-binding actin-bundling protein (actinin), alpha chain (EF-Hand protein superfamily)[Z], KOG0517-Beta-spectrin[Z]]"]
["TXN",2781.516602,422.794861,-2.71784197,0,0,"down","TXN","thioredoxin","GO:0004791;GO:0005576;GO:0005634;GO:0005737;GO:0006351;GO:0006355;GO:0006662;GO:0009314;GO:0015035;GO:0016671;GO:0033158;GO:0034599;GO:0043388;GO:0045454;GO:0047134;GO:0055114;GO:0098869","-","KOG0907-Thioredoxin[O]"]
["DHDH",25.33206,3.847186,-2.719088915,{"v":4.2e-132,"d":"4.20E-132"},{"v":3.42e-131,"d":"3.42E-131"},"down","DHDH","-","GO:0016491;GO:0055114","K00078-ko00040 Pentose and glucuronate interconversions;ko00980 Metabolism of xenobiotics by cytochrome P450","KOG2741-Dimeric dihydrodiol dehydrogenase[GQ]"]
["S100A9",108.749626,16.493759,-2.721018302,{"v":5.83e-214,"d":"5.83E-214"},{"v":6.78e-213,"d":"6.78E-213"},"down","S100A9","S100 calcium binding protein A9","-","-","-"]
["TAC1",21.596579,3.260546,-2.727617322,{"v":2.09e-77,"d":"2.09E-77"},{"v":1.19e-76,"d":"1.19E-76"},"down","TAC1","-","GO:0005102;GO:0005576;GO:0005615;GO:0006954;GO:0007204;GO:0007217;GO:0007267;GO:0019233;GO:0030424;GO:0043025;GO:0048265;GO:1990090","K05239-ko04080 Neuroactive ligand-receptor interaction","-"]
["HTR2B",5.207969,0.782414,-2.734716771,{"v":1.86e-72,"d":"1.86E-72"},{"v":1.02e-71,"d":"1.02E-71"},"down","HTR2B","5-hydroxytryptamine receptor 2B","GO:0001755;GO:0001819;GO:0001938;GO:0001965;GO:0002031;GO:0003007;GO:0003300;GO:0004930;GO:0004993;GO:0005096;GO:0005654;GO:0005737;GO:0005886;GO:0005887;GO:0006874;GO:0006939;GO:0007165;GO:0007186;GO:0007200;GO:0007202;GO:0007205;GO:0007210;GO:0007507;GO:0008144;GO:0008284;GO:0010507;GO:0010513;GO:0014033;GO:0014065;GO:0014827;GO:0016020;GO:0016021;GO:0016310;GO:0019722;GO:0019934;GO:0030594;GO:0042310;GO:0042493;GO:0043066;GO:0043123;GO:0043406;GO:0043547;GO:0048598;GO:0050715;GO:0050795;GO:0051000;GO:0051209;GO:0051378;GO:0051781;GO:0060548;GO:0070371;GO:0070374;GO:0070528;GO:0071502;GO:0098664","K04157-ko04020 Calcium signaling pathway;ko04080 Neuroactive ligand-receptor interaction;ko04540 Gap junction;ko04726 Serotonergic synapse;ko04750 Inflammatory mediator regulation of TRP channels","KOG4220-Muscarinic acetylcholine receptor[T]"]
["LGALS1",815.985352,122.576698,-2.734858507,0,0,"down","LGALS1","galectin 1","-","-","KOG3587-Galectin, galactose-binding lectin[W]"]
["ENTPD3",28.832235,4.322668,-2.737688735,0,0,"down","ENTPD3","ectonucleoside triphosphate diphosphohydrolase 3","GO:0005886;GO:0009134;GO:0009143;GO:0016020;GO:0016021;GO:0016787;GO:0017110;GO:0017111","K01510-ko00230 Purine metabolism;ko00240 Pyrimidine metabolism;ko05169 Epstein-Barr virus infection","KOG1386-Nucleoside phosphatase[F]"]
["SMAGP",184.615097,27.607521,-2.741387282,0,0,"down","SMAGP","-","-","-","-"]
["ASPN",87.867607,13.080761,-2.747884929,0,0,"down","ASPN","-","GO:0004860;GO:0005509;GO:0005518;GO:0005737;GO:0006469;GO:0019221;GO:0030282;GO:0030512;GO:0031012;GO:0046426;GO:0070171","-","KOG4194-Membrane glycoprotein LIG-1[T]"]
["KPNA2",22.172037,3.290606,-2.752316119,{"v":3.81e-161,"d":"3.81E-161"},{"v":3.57e-160,"d":"3.57E-160"},"down","KPNA2","karyopherin subunit alpha 2","GO:0005634;GO:0005643;GO:0005654;GO:0005737;GO:0005829;GO:0006606;GO:0006607;GO:0008139;GO:0008565;GO:0015031;GO:0042826;GO:0061608;GO:0098892;GO:0098978;GO:0099527","K15043-ko05164 Influenza A","KOG0166-Karyopherin (importin) alpha[U]"]
["ZNF750",99.026985,14.680157,-2.753954318,0,0,"down","ZNF750","-","GO:0000978;GO:0005634;GO:0006366;GO:0008544;GO:0045944;GO:1990841","-","-"]
["PYGB",361.319366,53.562046,-2.753991607,0,0,"down","PYGB","glycogen phosphorylase B","GO:0004645;GO:0005623;GO:0005737;GO:0005975;GO:0005980;GO:0008184;GO:0016740;GO:0016757;GO:0030170;GO:0045177;GO:0048471;GO:0102250;GO:0102499","K00688-ko00500 Starch and sucrose metabolism;ko04910 Insulin signaling pathway;ko04922 Glucagon signaling pathway;ko04931 Insulin resistance","KOG2099-Glycogen phosphorylase[G]"]
["OVOL2",58.471207,8.624291,-2.761248609,0,0,"down","OVOL2","-","GO:0000122;GO:0000981;GO:0001227;GO:0001228;GO:0001525;GO:0001755;GO:0001842;GO:0001947;GO:0003676;GO:0003677;GO:0003682;GO:0005634;GO:0006357;GO:0006366;GO:0007507;GO:0008285;GO:0008544;GO:0009913;GO:0009953;GO:0010628;GO:0010629;GO:0010719;GO:0010837;GO:0045618;GO:0045892;GO:0045893;GO:0045944;GO:0048557;GO:0060214;GO:0060347;GO:0060390;GO:0071560;GO:2000647","-","KOG3576-Ovo and related transcription factors[K]"]
["RASGEF1B",45.020531,6.630692,-2.763351725,0,0,"down","RASGEF1B","-","-","-","KOG3541-Predicted guanine nucleotide exchange factor[T]"]
["KRT14",89.793205,13.220403,-2.763840119,0,0,"down","KRT14","keratin 14","GO:0005198;GO:0005634;GO:0005737;GO:0005882;GO:0030855;GO:0045095;GO:0045110","-","KOG0977-Nuclear envelope protein lamin, intermediate filament superfamily[DY]"]
["LOC112533410",51.218861,7.471615,-2.777183148,0,0,"down","LOC112533410","-","-","-","-"]
["SLC1A3",7.441581,1.083951,-2.77930962,{"v":8.05e-115,"d":"8.05E-115"},{"v":5.94e-114,"d":"5.94E-114"},"down","SLC1A3","-","GO:0005313;GO:0005314;GO:0005886;GO:0005887;GO:0006536;GO:0006537;GO:0007605;GO:0009416;GO:0009449;GO:0009611;GO:0009986;GO:0015172;GO:0015293;GO:0015501;GO:0015813;GO:0016020;GO:0016021;GO:0016595;GO:0016597;GO:0021545;GO:0031223;GO:0042493;GO:0042995;GO:0043005;GO:0043025;GO:0046677;GO:0048667;GO:0050806;GO:0050885;GO:0051938;GO:0070779;GO:0071805;GO:0071944;GO:0098712;GO:0140009;GO:1902476","-","KOG3787-Glutamate/aspartate and neutral amino acid transporters[E]"]
["HTR1B",64.646652,9.403871,-2.781249002,0,0,"down","HTR1B","5-hydroxytryptamine receptor 1B","GO:0002031;GO:0004930;GO:0004993;GO:0005737;GO:0005886;GO:0005887;GO:0007165;GO:0007186;GO:0007193;GO:0007198;GO:0007205;GO:0007268;GO:0008144;GO:0014063;GO:0016020;GO:0016021;GO:0030594;GO:0035690;GO:0042310;GO:0042493;GO:0046849;GO:0050795;GO:0051378;GO:0071312;GO:0071502;GO:0099056;GO:0099154;GO:1904707","K04153-ko04024 cAMP signaling pathway;ko04080 Neuroactive ligand-receptor interaction;ko04726 Serotonergic synapse;ko04742 Taste transduction","KOG4220-Muscarinic acetylcholine receptor[T]"]
["DLX5",9.062662,1.311311,-2.788924993,{"v":8.38e-43,"d":"8.38E-43"},{"v":3.49e-42,"d":"3.49E-42"},"down","DLX5","distal-less homeobox 5","GO:0000790;GO:0000978;GO:0001503;GO:0001649;GO:0001958;GO:0003677;GO:0005634;GO:0005737;GO:0006351;GO:0006355;GO:0006366;GO:0007275;GO:0007409;GO:0007411;GO:0008283;GO:0010628;GO:0021889;GO:0030326;GO:0030509;GO:0030855;GO:0042472;GO:0043565;GO:0043583;GO:0044212;GO:0045893;GO:0045944;GO:0048646;GO:0050679;GO:0060021;GO:0060166;GO:0060322;GO:0060325;GO:0060349;GO:0071773;GO:0071837;GO:0090263;GO:0097376;GO:1901522","-","KOG0850-Transcription factor DLX and related proteins with LIM Zn-binding and HOX domains[K]"]
["TP53INP2",143.531143,20.721127,-2.792189426,0,0,"down","TP53INP2","-","GO:0000045;GO:0005634;GO:0005776;GO:0010508;GO:0045893","-","-"]
["MAL2",94.64817,13.60844,-2.798072919,0,0,"down","MAL2","mal, T-cell differentiation protein 2","GO:0016020;GO:0016021;GO:0045056;GO:0045121","-","-"]
["SLC7A3",54.138973,7.749324,-2.804525151,0,0,"down","SLC7A3","-","GO:0006865;GO:0016020;GO:0016021;GO:0022857;GO:0055085;GO:1902475","-","KOG1286-Amino acid transporters[E]"]
["UPK3BL",2360.412354,336.918121,-2.808568984,0,0,"down","UPK3BL","-","-","-","-"]
["MBOAT2",25.544884,3.643975,-2.809449418,0,0,"down","MBOAT2","membrane bound O-acyltransferase domain containing 2","-","K13517-ko00561 Glycerolipid metabolism;ko00564 Glycerophospholipid metabolism","KOG2704-Predicted membrane protein[S]"]
["CALD1",500.378815,71.337143,-2.810295367,0,0,"down","CALD1","caldesmon 1","GO:0003779;GO:0005516;GO:0005623;GO:0005737;GO:0005856;GO:0006936;GO:0017022;GO:0030016;GO:0044548;GO:0045159;GO:1903611;GO:0003779;GO:0005516;GO:0005886;GO:0006936;GO:0015629;GO:0017022;GO:0043231","K12327-ko04270 Vascular smooth muscle contraction","-"]
["MRVI1",58.669487,8.358491,-2.811295963,0,0,"down","MRVI1","-","GO:0016020;GO:0016021","K12337-ko04022 cGMP - PKG signaling pathway;ko04270 Vascular smooth muscle contraction","-"]
["CYP3A5",315.319305,44.855793,-2.813447277,0,0,"down","CYP3A5","cytochrome P450 family 3 subfamily A member 5","GO:0004497;GO:0005506;GO:0005623;GO:0008202;GO:0008395;GO:0016020;GO:0016021;GO:0016324;GO:0016491;GO:0016705;GO:0016712;GO:0017144;GO:0020037;GO:0032451;GO:0042445;GO:0042448;GO:0043385;GO:0045177;GO:0046677;GO:0046872;GO:0050649;GO:0055114;GO:0070988;GO:1901615","K07424-ko00140 Steroid hormone biosynthesis;ko00591 Linoleic acid metabolism;ko00830 Retinol metabolism;ko05204 Chemical carcinogenesis","KOG0158-Cytochrome P450 CYP3/CYP5/CYP6/CYP9 subfamilies[Q]"]
["GSL",278.915009,39.441654,-2.822033613,0,0,"down","GSL","-","GO:0000166;GO:0003824;GO:0004356;GO:0005524;GO:0006542;GO:0006807;GO:0016874","K01915-ko01230 Biosynthesis of amino acids;ko00630 Glyoxylate and dicarboxylate metabolism;ko00910 Nitrogen metabolism;ko00250 Alanine, aspartate and glutamate metabolism;ko00220 Arginine biosynthesis;ko02020 Two-component system;ko04724 Glutamatergic synapse;ko04727 GABAergic synapse","-"]
["DCLK1",5.050048,0.713146,-2.82402773,{"v":4.9e-103,"d":"4.90E-103"},{"v":3.34e-102,"d":"3.34E-102"},"down","DCLK1","doublecortin like kinase 1","GO:0001764;GO:0004672;GO:0005524;GO:0005622;GO:0006468;GO:0007409;GO:0007420;GO:0009615;GO:0014069;GO:0018105;GO:0021952;GO:0030900;GO:0035556;GO:0048675;GO:0048813;GO:1900181","-","[KOG3757-Microtubule assembly protein Doublecortin and related proteins, contain DCX domain[DZ], KOG0032-Ca2+/calmodulin-dependent protein kinase, EF-Hand protein superfamily[T]]"]
["MYL9",1405.039551,196.715424,-2.836428756,0,0,"down","MYL9","myosin, light chain 9, regulatory","GO:0005509","K12755-ko04024 cAMP signaling pathway;ko04022 cGMP - PKG signaling pathway;ko04810 Regulation of actin cytoskeleton;ko04510 Focal adhesion;ko04530 Tight junction;ko04670 Leukocyte transendothelial migration;ko04921 Oxytocin signaling pathway;ko04270 Vascular smooth muscle contraction","KOG0031-Myosin regulatory light chain, EF-Hand protein superfamily[Z]"]
["CKAP2",10.944301,1.529194,-2.839336464,{"v":2.41e-108,"d":"2.41E-108"},{"v":1.7e-107,"d":"1.70E-107"},"down","CKAP2","cytoskeleton associated protein 2","-","-","-"]
["C26H1orf116",75.058601,10.448147,-2.8447703,0,0,"down","C26H1orf116","-","GO:0005737;GO:0005829;GO:0005886","-","-"]
["GRHL1",63.181557,8.734836,-2.854650969,0,0,"down","GRHL1","-","GO:0000978;GO:0001228;GO:0002934;GO:0005634;GO:0005654;GO:0005794;GO:0005829;GO:0006366;GO:0008544;GO:0031490;GO:0042803;GO:0043231;GO:0043565;GO:0044212;GO:0045616;GO:0045944;GO:0061436","-","-"]
["LOC107053421",8.247545,1.132803,-2.864067753,{"v":1.43e-44,"d":"1.43E-44"},{"v":6.09e-44,"d":"6.09E-44"},"down","LOC107053421","-","-","-","-"]
["LOC771811",119.893677,16.457443,-2.864943469,0,0,"down","LOC771811","-","-","-","-"]
["RNF223",22.629833,3.101907,-2.8669986,0,0,"down","RNF223","-","-","-","-"]
["DMRTA2",31.998476,4.346155,-2.880191663,{"v":8.75e-233,"d":"8.75E-233"},{"v":1.09e-231,"d":"1.09E-231"},"down","DMRTA2","-","GO:0002052;GO:0003700;GO:0005634;GO:0006355;GO:0021796;GO:0035914;GO:0042803;GO:0043565;GO:0046982;GO:0048665;GO:0071542","-","-"]
["CDKN1A",190.26355,25.841677,-2.8802276,0,0,"down","CDKN1A","cyclin dependent kinase inhibitor 1A","GO:0000079;GO:0000082;GO:0000086;GO:0000307;GO:0004860;GO:0004861;GO:0005634;GO:0005654;GO:0005730;GO:0005737;GO:0005829;GO:0006974;GO:0006977;GO:0006978;GO:0007050;GO:0007265;GO:0007346;GO:0008285;GO:0009411;GO:0010629;GO:0016604;GO:0019901;GO:0019912;GO:0030308;GO:0030332;GO:0030890;GO:0031625;GO:0031668;GO:0032991;GO:0033158;GO:0034198;GO:0042326;GO:0042771;GO:0043068;GO:0044877;GO:0045736;GO:0045860;GO:0048146;GO:0051726;GO:0070557;GO:0071479;GO:0071480;GO:0071493;GO:0071850;GO:0072331;GO:0090398;GO:0090399;GO:1904030;GO:1904031;GO:1904706;GO:2000134;GO:2000278;GO:2000379","K06625-ko04012 ErbB signaling pathway;ko04630 Jak-STAT signaling pathway;ko04066 HIF-1 signaling pathway;ko04068 FoxO signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04110 Cell cycle;ko04115 p53 signaling pathway;ko04921 Oxytocin signaling pathway;ko05200 Pathways in cancer;ko05202 Transcriptional misregulation in cancers;ko05206 MicroRNAs in cancer;ko05205 Proteoglycans in cancer;ko05203 Viral carcinogenesis;ko05214 Glioma;ko05220 Chronic myeloid leukemia;ko05218 Melanoma;ko05219 Bladder cancer;ko05215 Prostate cancer;ko05224 Breast cancer;ko05166 HTLV-I infection;ko05161 Hepatitis B;ko05160 Hepatitis C;ko05169 Epstein-Barr virus infection;ko01522 Endocrine resistance;ko01524 Platinum drug resistance","KOG4743-Cyclin-dependent kinase inhibitor[T]"]
["STMN2",18.506508,2.479026,-2.900187391,{"v":1.01e-60,"d":"1.01E-60"},{"v":5.04e-60,"d":"5.04E-60"},"down","STMN2","stathmin 2","GO:0031110;GO:0005737;GO:0007019;GO:0007026;GO:0010976;GO:0010977;GO:0015631;GO:0016020;GO:0030027;GO:0030424;GO:0030426;GO:0031110;GO:0031115;GO:0031117;GO:0031175;GO:0042995;GO:0043005;GO:0043025;GO:0048306;GO:0048471;GO:0051493;GO:1990090","-","-"]
["FAM83G",20.010117,2.678081,-2.901458101,{"v":1.93e-210,"d":"1.93E-210"},{"v":2.21e-209,"d":"2.21E-209"},"down","FAM83G","-","GO:0005634;GO:0005829;GO:0030509","-","-"]
["PPL",618.237305,82.720871,-2.901837429,0,0,"down","PPL","-","GO:0005856;GO:0009612","-","KOG0516-Dystonin, GAS (Growth-arrest-specific protein), and related proteins[Z]"]
["RACGAP1",7.861927,1.051745,-2.902098008,{"v":3.18e-63,"d":"3.18E-63"},{"v":1.62e-62,"d":"1.62E-62"},"down","RACGAP1","-","GO:0000281;GO:0000915;GO:0005096;GO:0005547;GO:0005634;GO:0005654;GO:0007165;GO:0007283;GO:0007405;GO:0008017;GO:0008272;GO:0019901;GO:0030496;GO:0031234;GO:0032154;GO:0032467;GO:0035556;GO:0043014;GO:0043015;GO:0043547;GO:0045995;GO:0046872;GO:0048487;GO:0051233;GO:0051256;GO:0051988;GO:0072686;GO:0097149","-","KOG3564-GTPase-activating protein[R]"]
["MYOCD",39.501949,5.284039,-2.902210817,0,0,"down","MYOCD","myocardin","GO:0000122;GO:0000790;GO:0000978;GO:0000987;GO:0001076;GO:0001228;GO:0001560;GO:0001570;GO:0001666;GO:0003231;GO:0003257;GO:0003713;GO:0005634;GO:0006357;GO:0006366;GO:0007507;GO:0008134;GO:0008284;GO:0008285;GO:0010628;GO:0010667;GO:0010832;GO:0030511;GO:0035035;GO:0035065;GO:0035886;GO:0042692;GO:0042826;GO:0043388;GO:0043954;GO:0045661;GO:0045736;GO:0045893;GO:0045944;GO:0045987;GO:0048286;GO:0048565;GO:0051091;GO:0051145;GO:0051152;GO:0055007;GO:0055012;GO:0060065;GO:0061629;GO:0070412;GO:0097070;GO:1900222;GO:1900239;GO:1901228;GO:1904706;GO:1904753;GO:2000587;GO:2000721;GO:2000727;GO:2001015","-","-"]
["PERP2",463.017303,61.292122,-2.91729255,0,0,"down","PERP2","PERP2, TP53 apoptosis effector","GO:0016020;GO:0016021","K10136-ko04115 p53 signaling pathway","KOG4671-Brain cell membrane protein 1 (BCMP1)[R]"]
["PLEKHA6",80.695503,10.681438,-2.917382393,0,0,"down","PLEKHA6","-","-","-","[KOG3531-Rho guanine nucleotide exchange factor CDEP[T], KOG0930-Guanine nucleotide exchange factor Cytohesin, contains PH and Sec7 domains[U]]"]
["SH3BGRL2",41.987961,5.5502,-2.919364066,0,0,"down","SH3BGRL2","-","-","-","KOG4023-Uncharacterized conserved protein[S]"]
["CAPN8",7.498883,0.963748,-2.959947848,{"v":3.04e-152,"d":"3.04E-152"},{"v":2.73e-151,"d":"2.73E-151"},"down","CAPN8","-","-","-","KOG0045-Cytosolic Ca2+-dependent cysteine protease (calpain), large subunit (EF-Hand protein superfamily)[OT]"]
["EVPL",81.340675,10.360011,-2.972951428,0,0,"down","EVPL","-","GO:0001533;GO:0005198;GO:0005829;GO:0005856;GO:0008544;GO:0019215;GO:0045111","-","-"]
["CDCA3",8.848074,1.126935,-2.972959146,{"v":6.79e-38,"d":"6.79E-38"},{"v":2.66e-37,"d":"2.66E-37"},"down","CDCA3","cell division cycle associated 3","GO:0005913;GO:0007049","-","-"]
["MIR147-1",458.669891,58.328964,-2.975171851,{"v":2.6e-119,"d":"2.60E-119"},{"v":1.97e-118,"d":"1.97E-118"},"down","MIR147-1","microRNA 147-1","-","-","-"]
["UBE2C",16.150705,2.051977,-2.976510676,{"v":8.26e-52,"d":"8.26E-52"},{"v":3.78e-51,"d":"3.78E-51"},"down","UBE2C","-","GO:0000151;GO:0000166;GO:0000209;GO:0004842;GO:0005524;GO:0005634;GO:0005680;GO:0005737;GO:0005829;GO:0005886;GO:0006511;GO:0010458;GO:0010994;GO:0016567;GO:0016740;GO:0030071;GO:0031145;GO:0031536;GO:0031625;GO:0044389;GO:0061630;GO:0061631;GO:0070936;GO:0070979","K06688-ko04120 Ubiquitin mediated proteolysis","KOG0421-Ubiquitin-protein ligase[O]"]
["NOXA1",41.62859,5.288773,-2.976569734,0,0,"down","NOXA1","-","GO:0006801;GO:0010310;GO:0016176;GO:0017124;GO:0019899;GO:0043020;GO:0043085;GO:0048365;GO:0060263","-","KOG4225-Sorbin and SH3 domain-containing protein[T]"]
["TMEM154",41.213673,5.233994,-2.977138868,0,0,"down","TMEM154","-","GO:0016020;GO:0016021","-","-"]
["PRDM1",26.304422,3.339995,-2.977387501,0,0,"down","PRDM1","-","GO:0005737","-","KOG2461-Transcription factor BLIMP-1/PRDI-BF1, contains C2H2-type Zn-finger and SET domains[K]"]
["PLAU",16.228531,2.049389,-2.985266656,{"v":8.95e-146,"d":"8.95E-146"},{"v":7.8e-145,"d":"7.80E-145"},"down","PLAU","plasminogen activator, urokinase","GO:0001666;GO:0004252;GO:0005576;GO:0005615;GO:0006508;GO:0008233;GO:0008236;GO:0009986;GO:0010469;GO:0014909;GO:0014910;GO:0016787;GO:0030335;GO:0031639;GO:0033628;GO:0042127;GO:0042730;GO:2000097","-","KOG3627-Trypsin[E]"]
["JAML",10.181661,1.282949,-2.98843721,{"v":5.28e-80,"d":"5.28E-80"},{"v":3.07e-79,"d":"3.07E-79"},"down","JAML","-","GO:0016020;GO:0016021;GO:0046629;GO:0050900","-","-"]
["IGSF3",80.737457,10.157539,-2.990687243,0,0,"down","IGSF3","-","GO:0016020;GO:0016021","-","-"]
["MATK",10.863393,1.365359,-2.992122535,{"v":5.6e-89,"d":"5.60E-89"},{"v":3.49e-88,"d":"3.49E-88"},"down","MATK","-","GO:0000166;GO:0004672;GO:0004713;GO:0004715;GO:0005102;GO:0005524;GO:0006468;GO:0007169;GO:0016301;GO:0016310;GO:0016740;GO:0030154;GO:0031234;GO:0038083;GO:0042127;GO:0045087","-","KOG0197-Tyrosine kinases[T]"]
["RAB39A",12.446205,1.563004,-2.993312538,{"v":1.71e-176,"d":"1.71E-176"},{"v":1.71e-175,"d":"1.71E-175"},"down","RAB39A","-","GO:0003924;GO:0005525;GO:0005794;GO:0045335;GO:0090383;GO:0090385","-","KOG0091-GTPase Rab39, small G protein superfamily[R]"]
["EAF2",99.2463,12.440035,-2.996022774,0,0,"down","EAF2","ELL associated factor 2","GO:0000977;GO:0001228;GO:0005654;GO:0006355;GO:0006366;GO:0008023;GO:0030308;GO:0032783;GO:0045893;GO:0045944;GO:0060770;GO:0000977;GO:0001228;GO:0005634;GO:0005654;GO:0006351;GO:0006355;GO:0006366;GO:0008023;GO:0016607;GO:0030308;GO:0032783;GO:0045893;GO:0045944;GO:0060770","-","KOG4795-Protein associated with transcriptional elongation factor ELL[K]"]
["TUBA3E",131.51088,16.387316,-3.004530673,0,0,"down","TUBA3E","tubulin, alpha 3e","GO:0000166;GO:0003924;GO:0005200;GO:0005525;GO:0005737;GO:0005856;GO:0005874;GO:0007010;GO:0007017","K07374-ko04145 Phagosome;ko04210 Apoptosis;ko04540 Gap junction;ko05130 Pathogenic Escherichia coli infection","KOG1376-Alpha tubulin[Z]"]
["NIPAL1",29.879698,3.721864,-3.005068322,0,0,"down","NIPAL1","-","GO:0015095;GO:0015693;GO:0016020;GO:0016021;GO:1903830","-","KOG2922-Uncharacterized conserved protein[S]"]
["FHDC1",8.792655,1.094277,-3.006320881,{"v":7.71e-288,"d":"7.71E-288"},{"v":1.12e-286,"d":"1.12E-286"},"down","FHDC1","-","-","-","-"]
["LOC422224",86.593025,10.759604,-3.00862584,0,0,"down","LOC422224","-","GO:0016020;GO:0016021","-","-"]
["FAM83H",58.255222,7.174705,-3.021395959,0,0,"down","FAM83H","-","GO:0019901;GO:0030335;GO:0044380;GO:0045095;GO:0045104;GO:1990254","-","-"]
["SLC45A3",14.556876,1.775501,-3.035402699,0,0,"down","SLC45A3","-","GO:0008506;GO:0010907;GO:0015770;GO:0016020;GO:0016021;GO:0045723;GO:0048713;GO:0055085","-","KOG0637-Sucrose transporter and related proteins[G]"]
["PHLDA1",132.192627,16.025978,-3.044157407,0,0,"down","PHLDA1","-","GO:0005634;GO:0005730;GO:0045210","-","-"]
["SYT8",83.408257,10.101876,-3.045566972,0,0,"down","SYT8","-","GO:0005509;GO:0005544;GO:0005737;GO:0005886;GO:0006887;GO:0006906;GO:0007340;GO:0016020;GO:0016021;GO:0017158;GO:0019905;GO:0030276;GO:0030672;GO:0031982;GO:0048306;GO:0048488;GO:0048791","-","KOG1028-Ca2+-dependent phospholipid-binding protein Synaptotagmin, required for synaptic vesicle and secretory granule exocytosis[TU]"]
["PRIMA1",28.866058,3.492144,-3.047189149,{"v":1.6e-60,"d":"1.60E-60"},{"v":7.98e-60,"d":"7.98E-60"},"down","PRIMA1","proline rich membrane anchor 1","GO:0016020;GO:0016021","-","-"]
["COL17A1",103.67778,12.529651,-3.048688596,0,0,"down","COL17A1","collagen type XVII alpha 1 chain","GO:0005576;GO:0005581;GO:0005604;GO:0016020;GO:0016021;GO:0030054;GO:0030056;GO:0016020;GO:0016021;GO:0030056;GO:0031581","-","-"]
["SERPINB5",297.77121,35.973335,-3.049204454,0,0,"down","SERPINB5","-","GO:0002009;GO:0004867;GO:0005615;GO:0005737;GO:0010951;GO:0030198;GO:0050678;GO:0060512","K10139-ko04115 p53 signaling pathway;ko05206 MicroRNAs in cancer","KOG2392-Serpin[V]"]
["CACNB2",11.389481,1.373437,-3.051839367,{"v":5.1e-301,"d":"5.10E-301"},{"v":7.78e-300,"d":"7.78E-300"},"down","CACNB2","-","GO:0005245;GO:0005891;GO:0007268;GO:0007528;GO:0007601;GO:0008331;GO:0051015;GO:0051928;GO:0070509;GO:0070588;GO:0086007;GO:0086045;GO:0086056;GO:0086091;GO:0098912;GO:1901385;GO:1990454","K04863-ko04010 MAPK signaling pathway;ko04921 Oxytocin signaling pathway;ko04260 Cardiac muscle contraction;ko04261 Adrenergic signaling in cardiomyocytes;ko05410 Hypertrophic cardiomyopathy (HCM);ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC);ko05414 Dilated cardiomyopathy (DCM)","KOG3812-L-type voltage-dependent Ca2+ channel, beta subunit[PT]"]
["C14H16orf45",112.250732,13.418167,-3.064465343,0,0,"down","C14H16orf45","chromosome 14 C16orf45 homolog","GO:0007026;GO:0015630;GO:0021822","-","-"]
["B3GNT5",36.169209,4.286136,-3.077012515,0,0,"down","B3GNT5","UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5","GO:0000139;GO:0005622;GO:0005794;GO:0006486;GO:0007417;GO:0008378;GO:0008457;GO:0016020;GO:0016021;GO:0016740;GO:0016757","K03766-ko00601 Glycosphingolipid biosynthesis - lacto and neolacto series","KOG2287-Galactosyltransferases[G]"]
["RAB7B",95.313347,11.252386,-3.082447304,0,0,"down","RAB7B","-","GO:0003924;GO:0005525;GO:0005764;GO:0005770;GO:0005794;GO:0005802;GO:0032755;GO:0034144;GO:0034164;GO:0034499;GO:0045335;GO:0045654;GO:0051092;GO:0071346","K07898-ko04145 Phagosome;ko05132 Salmonella infection;ko05146 Amoebiasis","KOG0394-Ras-related GTPase[R]"]
["AHR2",35.556034,4.165106,-3.093669295,0,0,"down","AHR2","aryl hydrocarbon receptor 2","GO:0001046;GO:0003677;GO:0004874;GO:0005634;GO:0005667;GO:0006351;GO:0006355;GO:0006805;GO:0009410;GO:0014070;GO:0034751;GO:0034753;GO:0043425;GO:0045893;GO:0045944;GO:0046982;GO:0046983","-","KOG3560-Aryl-hydrocarbon receptor[K]"]
["NKX6-1",939.947021,109.623215,-3.100026092,0,0,"down","NKX6-1","-","GO:0001764;GO:0003309;GO:0003677;GO:0003700;GO:0005634;GO:0006355;GO:0006357;GO:0007224;GO:0021912;GO:0021913;GO:0021953;GO:0030154;GO:0030516;GO:0031018;GO:0043565;GO:0045666;GO:0045686;GO:0045687;GO:0048709;GO:0050796;GO:2001222","-","KOG0847-Transcription factor, contains HOX domain[K]"]
["TOP2A",10.322533,1.199001,-3.105892264,{"v":2.06e-231,"d":"2.06E-231"},{"v":2.55e-230,"d":"2.55E-230"},"down","TOP2A","topoisomerase (DNA) II alpha","GO:0000166;GO:0000228;GO:0000287;GO:0000712;GO:0000792;GO:0000793;GO:0000819;GO:0002244;GO:0003677;GO:0003682;GO:0003916;GO:0003918;GO:0005080;GO:0005524;GO:0005634;GO:0005654;GO:0005694;GO:0005730;GO:0005814;GO:0006259;GO:0006260;GO:0006265;GO:0006266;GO:0006974;GO:0007059;GO:0007143;GO:0008022;GO:0008094;GO:0008144;GO:0008283;GO:0008301;GO:0009330;GO:0016020;GO:0016021;GO:0016853;GO:0019899;GO:0030261;GO:0030263;GO:0030332;GO:0032991;GO:0040016;GO:0042752;GO:0042803;GO:0042826;GO:0043065;GO:0043130;GO:0044774;GO:0045070;GO:0045870;GO:0045944;GO:0046872;GO:0046982;GO:0048511;GO:0061505;GO:1905463;GO:1990904","-","KOG0355-DNA topoisomerase type II[B]"]
["CALML3",272.44574,31.225655,-3.125165193,0,0,"down","CALML3","calmodulin like 3","GO:0005509;GO:0005622;GO:0019722","K02183-ko04014 Ras signaling pathway;ko04015 Rap1 signaling pathway;ko04020 Calcium signaling pathway;ko04070 Phosphatidylinositol signaling system;ko04024 cAMP signaling pathway;ko04022 cGMP - PKG signaling pathway;ko04114 Oocyte meiosis;ko04910 Insulin signaling pathway;ko04922 Glucagon signaling pathway;ko04912 GnRH signaling pathway;ko04915 Estrogen signaling pathway;ko04921 Oxytocin signaling pathway;ko04916 Melanogenesis;ko04924 Renin secretion;ko04925 Aldosterone synthesis and secretion;ko04261 Adrenergic signaling in cardiomyocytes;ko04270 Vascular smooth muscle contraction;ko04970 Salivary secretion;ko04971 Gastric acid secretion;ko04728 Dopaminergic synapse;ko04720 Long-term potentiation;ko04722 Neurotrophin signaling pathway;ko04744 Phototransduction;ko04745 Phototransduction - fly;ko04740 Olfactory transduction;ko04750 Inflammatory mediator regulation of TRP channels;ko04713 Circadian entrainment;ko04626 Plant-pathogen interaction;ko05214 Glioma;ko05010 Alzheimer's disease;ko05031 Amphetamine addiction;ko05034 Alcoholism;ko05133 Pertussis;ko05152 Tuberculosis","KOG0027-Calmodulin and related proteins (EF-Hand superfamily)[T]"]
["PAQR5",80.634636,9.222754,-3.128130148,0,0,"down","PAQR5","-","GO:0003707;GO:0005496;GO:0005886;GO:0016020;GO:0016021;GO:0043401;GO:0048545","-","-"]
["F10",12.949289,1.458865,-3.149954596,{"v":4.35e-116,"d":"4.35E-116"},{"v":3.24e-115,"d":"3.24E-115"},"down","F10","coagulation factor X","GO:0004252;GO:0005509;GO:0005543;GO:0005576;GO:0006508;GO:0007596;GO:0007599;GO:0008233;GO:0008236;GO:0016787;GO:0051897","-","KOG3627-Trypsin[E]"]
["E2F8",19.997417,2.241169,-3.157490316,{"v":2.37e-302,"d":"2.37E-302"},{"v":3.62e-301,"d":"3.62E-301"},"down","E2F8","-","GO:0000122;GO:0000978;GO:0000987;GO:0002040;GO:0003677;GO:0003700;GO:0003714;GO:0005634;GO:0005667;GO:0005730;GO:0005829;GO:0006351;GO:0006355;GO:0008283;GO:0032466;GO:0032877;GO:0033301;GO:0042802;GO:0042803;GO:0045944;GO:0060718;GO:0070365","-","KOG2578-Transcription factor E2F/dimerization partner (TDP)-like proteins[K]"]
["GPR171",5.345267,0.595215,-3.166779224,{"v":1.05e-38,"d":"1.05E-38"},{"v":4.17e-38,"d":"4.17E-38"},"down","GPR171","G protein-coupled receptor 171","GO:0004930;GO:0007165;GO:0007186;GO:0016020;GO:0016021;GO:0045638","-","-"]
["MYRIP",16.507717,1.834645,-3.169567774,0,0,"down","MYRIP","-","-","-","-"]
["MXD1",104.975418,11.664843,-3.169812738,0,0,"down","MXD1","MAX dimerization protein 1","GO:0000122;GO:0000790;GO:0000978;GO:0005654;GO:0005739;GO:0005829;GO:0046983","-","KOG2483-Upstream transcription factor 2/L-myc-2 protein[K]"]
["ANKRD22",43.374737,4.804235,-3.174476382,0,0,"down","ANKRD22","ankyrin repeat domain 22","GO:0016020;GO:0016021","-","KOG4177-Ankyrin[M]"]
["DSC1",136.81041,15.060141,-3.183370828,0,0,"down","DSC1","-","GO:0005509;GO:0005886;GO:0007155;GO:0007156;GO:0016020;GO:0016021","-","-"]
["LOC770492",28.156548,3.088315,-3.188578654,{"v":3.59e-218,"d":"3.59E-218"},{"v":4.24e-217,"d":"4.24E-217"},"down","LOC770492","-","GO:0000166;GO:0003924;GO:0005525;GO:0007165;GO:0016020","-","-"]
["TP63",98.600494,10.757436,-3.196260618,0,0,"down","TP63","tumor protein p63","GO:0000122;GO:0000790;GO:0001501;GO:0001736;GO:0001738;GO:0002039;GO:0002053;GO:0002064;GO:0003677;GO:0003682;GO:0003684;GO:0003700;GO:0005634;GO:0005654;GO:0005737;GO:0005794;GO:0005829;GO:0006338;GO:0006355;GO:0006366;GO:0006915;GO:0007389;GO:0007499;GO:0007569;GO:0008283;GO:0008544;GO:0009887;GO:0009913;GO:0009954;GO:0010259;GO:0010481;GO:0010482;GO:0010838;GO:0030154;GO:0030216;GO:0030326;GO:0030850;GO:0030855;GO:0030859;GO:0032502;GO:0033147;GO:0035115;GO:0035116;GO:0036342;GO:0042771;GO:0042802;GO:0043066;GO:0043281;GO:0043565;GO:0043589;GO:0043616;GO:0044212;GO:0045617;GO:0045669;GO:0045747;GO:0045892;GO:0045893;GO:0045944;GO:0048485;GO:0048646;GO:0048745;GO:0048807;GO:0050699;GO:0051262;GO:0051289;GO:0051402;GO:0060197;GO:0060513;GO:0060529;GO:0061436;GO:0097371;GO:0098773;GO:1904674;GO:1904888;GO:2000271;GO:2000381;GO:2001235","-","-"]
["LOC769668",47.374809,5.108921,-3.213029594,{"v":1.58e-167,"d":"1.58E-167"},{"v":1.52e-166,"d":"1.52E-166"},"down","LOC769668","estradiol 17-beta-dehydrogenase 2-like","-","-","-"]
["AADAC",120.429169,12.981515,-3.213654201,0,0,"down","AADAC","-","GO:0008152;GO:0009056;GO:0016021;GO:0016787;GO:0052689","-","KOG1515-Arylacetamide deacetylase[V]"]
["CMC4",12.598077,1.355883,-3.215898936,{"v":7.04e-186,"d":"7.04E-186"},{"v":7.28e-185,"d":"7.28E-185"},"down","CMC4","-","GO:0005739;GO:0005758","-","-"]
["CHAC1",161.156326,17.315992,-3.218283877,0,0,"down","CHAC1","ChaC glutathione specific gamma-glutamylcyclotransferase 1","GO:0003839;GO:0005112;GO:0005737;GO:0005802;GO:0005829;GO:0006751;GO:0010955;GO:0016829;GO:0022008;GO:0045746;GO:0070059","-","KOG3182-Predicted cation transporter[P]"]
["PPP1R12A",276.250519,29.534346,-3.225511604,0,0,"down","PPP1R12A","protein phosphatase 1 regulatory subunit 12A","GO:0007165;GO:0019208;GO:0019901;GO:0050790;GO:0000278;GO:0000776;GO:0004857;GO:0005737;GO:0005813;GO:0005829;GO:0006470;GO:0007098;GO:0007165;GO:0015629;GO:0019208;GO:0019901;GO:0030018;GO:0030155;GO:0031672;GO:0035507;GO:0035508;GO:0035690;GO:0043086;GO:0043292;GO:0045944;GO:0046822;GO:0071889;GO:0072357","K06270-ko04024 cAMP signaling pathway;ko04022 cGMP - PKG signaling pathway;ko04810 Regulation of actin cytoskeleton;ko04510 Focal adhesion;ko04611 Platelet activation;ko04921 Oxytocin signaling pathway;ko04270 Vascular smooth muscle contraction;ko05205 Proteoglycans in cancer","KOG0505-Myosin phosphatase, regulatory subunit[OT]"]
["HAPLN3",50.147594,5.335138,-3.232582991,0,0,"down","HAPLN3","-","GO:0001501;GO:0005201;GO:0005540;GO:0007155;GO:0007417","-","-"]
["MIR22",40.851578,4.322659,-3.240400871,{"v":1.93e-08,"d":"1.93E-08"},{"v":3.94e-08,"d":"3.94E-08"},"down","MIR22","microRNA 22","-","-","-"]
["MFSD4A",78.218269,8.23739,-3.247246409,0,0,"down","MFSD4A","-","GO:0005355;GO:0016020;GO:0016021;GO:1904659","-","-"]
["KLF-4",161.630127,16.989681,-3.249965464,0,0,"down","KLF-4","-","-","-","-"]
["RBBP8NL",10.161396,1.066917,-3.251578765,{"v":3.33e-132,"d":"3.33E-132"},{"v":2.71e-131,"d":"2.71E-131"},"down","RBBP8NL","-","-","-","-"]
["KLHDC8A",8.304383,0.868869,-3.2566624,{"v":2.25e-143,"d":"2.25E-143"},{"v":1.93e-142,"d":"1.93E-142"},"down","KLHDC8A","-","GO:0004842;GO:0016567;GO:0031463","-","KOG4441-Proteins containing BTB/POZ and Kelch domains, involved in regulatory/signal transduction processes[TR]"]
["FAM83B",9.395264,0.974685,-3.268925754,0,0,"down","FAM83B","-","GO:0005154;GO:0005737;GO:0007173;GO:0008283;GO:0016020;GO:0019901;GO:0036312;GO:0036313","-","-"]
["SCUBE2",27.065517,2.750933,-3.298463039,0,0,"down","SCUBE2","-","GO:0005509","-","KOG1217-Fibrillins and related proteins containing Ca2+-binding EGF-like domains[T]"]
["PDZK1IP1",248.349289,25.089001,-3.307243685,0,0,"down","PDZK1IP1","PDZK1 interacting protein 1","GO:0016020;GO:0016021","-","-"]
["FLNA",126.39608,12.740505,-3.310457353,0,0,"down","FLNA","filamin A","-","K04437-ko04010 MAPK signaling pathway;ko04510 Focal adhesion;ko05205 Proteoglycans in cancer;ko05132 Salmonella infection","-"]
["AADACL4L1",6.08103,0.607192,-3.324091019,{"v":7.47e-41,"d":"7.47E-41"},{"v":3.05e-40,"d":"3.05E-40"},"down","AADACL4L1","-","GO:0008152;GO:0016021;GO:0016787;GO:0052689","-","-"]
["ZNRF2",89.347656,8.91912,-3.324456602,0,0,"down","ZNRF2","-","GO:0005737;GO:0005886;GO:0016567;GO:0030659;GO:0032991;GO:0061630","-","KOG0801-Predicted E3 ubiquitin ligase[O]"]
["KRT8",507.388519,50.538712,-3.327630073,0,0,"down","KRT8","-","-","-","-"]
["LOC112530107",9.73689,0.956754,-3.347241111,{"v":1.12e-63,"d":"1.12E-63"},{"v":5.71e-63,"d":"5.71E-63"},"down","LOC112530107","-","-","-","-"]
["TMEFF2",50.006226,4.907264,-3.349116936,0,0,"down","TMEFF2","-","-","-","-"]
["PROC",5.369636,0.523274,-3.359185811,{"v":1.07e-21,"d":"1.07E-21"},{"v":3.21e-21,"d":"3.21E-21"},"down","PROC","protein C, inactivator of coagulation factors Va and VIIIa","GO:0001889;GO:0004252;GO:0005509;GO:0005576;GO:0005615;GO:0005783;GO:0005794;GO:0006508;GO:0007596;GO:0008233;GO:0008236;GO:0016787;GO:0030195;GO:0043066;GO:0044537;GO:0050728;GO:0050819;GO:1903142","-","-"]
["METTL24",5.408927,0.526495,-3.360850691,{"v":9.39e-39,"d":"9.39E-39"},{"v":3.72e-38,"d":"3.72E-38"},"down","METTL24","-","-","-","-"]
["GRHL3",63.928513,6.203389,-3.365331036,0,0,"down","GRHL3","-","GO:0000981;GO:0001228;GO:0001736;GO:0001843;GO:0003677;GO:0003700;GO:0005634;GO:0005654;GO:0006357;GO:0006366;GO:0007389;GO:0007398;GO:0007417;GO:0008544;GO:0010628;GO:0031490;GO:0032956;GO:0042060;GO:0043547;GO:0043565;GO:0045893;GO:0045944;GO:0061029;GO:0061436;GO:0090103;GO:0090179","-","KOG4091-Transcription factor[K]"]
["NSG1",9.165243,0.88571,-3.371266819,{"v":3.26e-69,"d":"3.26E-69"},{"v":1.75e-68,"d":"1.75E-68"},"down","NSG1","neuron specific gene family member 1","GO:0001881;GO:0005764;GO:0005768;GO:0005770;GO:0005783;GO:0005794;GO:0006915;GO:0007212;GO:0010008;GO:0016020;GO:0016021;GO:0016197;GO:0016328;GO:0030425;GO:0030659;GO:0031410;GO:0031901;GO:0031902;GO:0032051;GO:0032580;GO:0032585;GO:0042982;GO:0042995;GO:0043202;GO:0045211;GO:0048268;GO:0055038;GO:0098887;GO:0098978;GO:0099003;GO:0099627","-","-"]
["KCNIP1",13.405503,1.293291,-3.373706519,{"v":2.32e-61,"d":"2.32E-61"},{"v":1.16e-60,"d":"1.16E-60"},"down","KCNIP1","-","GO:0005509;GO:0005737;GO:0008076;GO:0015459;GO:0031234;GO:1901379","-","KOG0044-Ca2+ sensor (EF-Hand superfamily)[T]"]
["CDC20",30.0674,2.862943,-3.392629268,{"v":8.25e-209,"d":"8.25E-209"},{"v":9.43e-208,"d":"9.43E-208"},"down","CDC20","cell division cycle 20","GO:0010997;GO:0031145;GO:0097027;GO:1904668;GO:0005634;GO:0005654;GO:0005680;GO:0005829;GO:0007064;GO:0008022;GO:0010997;GO:0019899;GO:0031145;GO:0031915;GO:0040020;GO:0090129;GO:0090307;GO:0097027;GO:1904668","K03363-ko04120 Ubiquitin mediated proteolysis;ko04110 Cell cycle;ko04111 Cell cycle - yeast;ko04113 Meiosis - yeast;ko04114 Oocyte meiosis;ko05203 Viral carcinogenesis;ko05166 HTLV-I infection","KOG0305-Anaphase promoting complex, Cdc20, Cdh1, and Ama1 subunits[DO]"]
["BARX1",90.573898,8.623701,-3.392716285,0,0,"down","BARX1","BARX homeobox 1","GO:0000977;GO:0001228;GO:0003677;GO:0005634;GO:0006351;GO:0006355;GO:0006357;GO:0006366;GO:0007267;GO:0007399;GO:0009888;GO:0009952;GO:0030178;GO:0030855;GO:0043565;GO:0045944;GO:0048513;GO:0048536;GO:0048856;GO:0055123","-","[KOG0488-Transcription factor BarH and related HOX domain proteins[R], KOG0491-Transcription factor BSH, contains HOX domain[R]]"]
["SMC2",13.899343,1.310065,-3.407306391,{"v":4.04e-242,"d":"4.04E-242"},{"v":5.18e-241,"d":"5.18E-241"},"down","SMC2","structural maintenance of chromosomes 2","GO:0000228;GO:0000793;GO:0000796;GO:0003697;GO:0005524;GO:0005634;GO:0005694;GO:0005730;GO:0005737;GO:0007076;GO:0010032;GO:0045132;GO:0046982;GO:0051276;GO:0051383;GO:0000166;GO:0005524;GO:0005634;GO:0005694;GO:0005737;GO:0007049;GO:0030261;GO:0051276;GO:0051301","-","KOG0933-Structural maintenance of chromosome protein 2 (chromosome condensation complex Condensin, subunit E)[BD]"]
["RHBDL3",7.228749,0.679738,-3.410695315,{"v":1.94e-153,"d":"1.94E-153"},{"v":1.75e-152,"d":"1.75E-152"},"down","RHBDL3","-","GO:0004252;GO:0005509;GO:0006508;GO:0008233;GO:0016020;GO:0016021;GO:0016485;GO:0016787","-","KOG2289-Rhomboid family proteins[T]"]
["LOC101747602",5.982399,0.556257,-3.426900644,{"v":2.76e-43,"d":"2.76E-43"},{"v":1.16e-42,"d":"1.16E-42"},"down","LOC101747602","-","-","-","-"]
["LOC101750423",5.707394,0.529355,-3.430524697,{"v":1.45e-81,"d":"1.45E-81"},{"v":8.54e-81,"d":"8.54E-81"},"down","LOC101750423","-","-","-","-"]
["S100A6",6609.449707,608.309631,-3.441652409,0,0,"down","S100A6","S100 calcium binding protein A6","GO:0001726;GO:0005509;GO:0005523;GO:0005623;GO:0005634;GO:0005635;GO:0005737;GO:0005829;GO:0005886;GO:0007049;GO:0008270;GO:0019899;GO:0031234;GO:0042803;GO:0044548;GO:0046872;GO:0048306;GO:0048471;GO:0051781","-","-"]
["CAPN9",17.538635,1.593063,-3.460661243,0,0,"down","CAPN9","-","-","-","KOG0045-Cytosolic Ca2+-dependent cysteine protease (calpain), large subunit (EF-Hand protein superfamily)[OT]"]
["CYSRT1",97.626183,8.808593,-3.470284625,0,0,"down","CYSRT1","-","-","-","-"]
["FAM13C",20.301748,1.821557,-3.478359905,{"v":1.45e-276,"d":"1.45E-276"},{"v":2.05e-275,"d":"2.05E-275"},"down","FAM13C","-","-","-","-"]
["C24H11orf34",354.297424,31.700567,-3.482380426,0,0,"down","C24H11orf34","-","-","-","-"]
["SYT12",15.364847,1.374486,-3.482669284,{"v":2.52e-121,"d":"2.52E-121"},{"v":1.93e-120,"d":"1.93E-120"},"down","SYT12","synaptotagmin 12","GO:0005509;GO:0005544;GO:0005886;GO:0006906;GO:0016020;GO:0016021;GO:0017158;GO:0019905;GO:0030276;GO:0045202;GO:0046928;GO:0048791;GO:0060291;GO:0098793","-","KOG1028-Ca2+-dependent phospholipid-binding protein Synaptotagmin, required for synaptic vesicle and secretory granule exocytosis[TU]"]
["CPXM2",20.588589,1.840208,-3.483904212,0,0,"down","CPXM2","-","GO:0004181;GO:0004185;GO:0005615;GO:0006508;GO:0006518;GO:0008270;GO:0016485","-","-"]
["GPR68",12.580442,1.117224,-3.493192235,{"v":1.78e-212,"d":"1.78E-212"},{"v":2.06e-211,"d":"2.06E-211"},"down","GPR68","-","GO:0004930;GO:0007165;GO:0007186;GO:0016020;GO:0016021;GO:0032024;GO:0035774;GO:0045656;GO:0071467;GO:2001206","-","KOG4219-G protein-coupled receptor[T]"]
["GDPD2",103.423225,9.082989,-3.509249254,0,0,"down","GDPD2","-","GO:0005884;GO:0005886;GO:0006629;GO:0008081;GO:0008889;GO:0016020;GO:0016021;GO:0030027;GO:0045669;GO:0090527","-","KOG2258-Glycerophosphoryl diester phosphodiesterase[C]"]
["LIPML5",21.34449,1.873627,-3.509958015,{"v":8.79e-120,"d":"8.79E-120"},{"v":6.66e-119,"d":"6.66E-119"},"down","LIPML5","-","GO:0016042;GO:0016787;GO:0016788","K01052-ko00100 Steroid biosynthesis;ko04142 Lysosome","-"]
["DUSP5",38.77684,3.384342,-3.51824797,0,0,"down","DUSP5","-","GO:0000188;GO:0004721;GO:0004725;GO:0006470;GO:0008138;GO:0016311;GO:0016787;GO:0016791;GO:0017017;GO:0035335;GO:0035970","K04459-ko04010 MAPK signaling pathway","KOG1716-Dual specificity phosphatase[V]"]
["B3GNT7",63.86805,5.488121,-3.540710208,0,0,"down","B3GNT7","-","-","K09664-ko00533 Glycosaminoglycan biosynthesis - keratan sulfate","KOG2287-Galactosyltransferases[G]"]
["MIR6607",28.464901,2.4398,-3.544349288,{"v":4.27e-15,"d":"4.27E-15"},{"v":1.1e-14,"d":"1.10E-14"},"down","MIR6607","microRNA 6607","-","-","-"]
["NMUR1",7.307613,0.610002,-3.582514355,{"v":9.03e-37,"d":"9.03E-37"},{"v":3.47e-36,"d":"3.47E-36"},"down","NMUR1","neuromedin U receptor 1","GO:0001607;GO:0004930;GO:0005622;GO:0006816;GO:0006821;GO:0006939;GO:0007165;GO:0007186;GO:0007200;GO:0007202;GO:0007218;GO:0008188;GO:0016020;GO:0016021;GO:0019722;GO:0042924;GO:0048016","K05052-ko04080 Neuroactive ligand-receptor interaction","KOG4219-G protein-coupled receptor[T]"]
["GJB6",88.905266,7.37873,-3.590824443,0,0,"down","GJB6","gap junction protein beta 6","GO:0005886;GO:0005921;GO:0005922;GO:0007154;GO:0007605;GO:0016020;GO:0016021;GO:0030054","-","-"]
["LMOD1",318.68045,26.164801,-3.606411326,0,0,"down","LMOD1","-","GO:0003779;GO:0005523;GO:0005829;GO:0005865;GO:0006936;GO:0007015;GO:0030016;GO:0030239;GO:0030838;GO:0045010;GO:0051694","-","KOG3735-Tropomodulin and leiomodulin[Z]"]
["C5H15ORF62",13.262784,1.087059,-3.608881495,{"v":2.67e-109,"d":"2.67E-109"},{"v":1.9e-108,"d":"1.90E-108"},"down","C5H15ORF62","-","-","-","-"]
["FER1L6",17.207479,1.410036,-3.609231847,0,0,"down","FER1L6","-","GO:0009617;GO:0016020;GO:0016021","-","KOG1326-Membrane-associated protein FER-1 and related ferlins, contain multiple C2 domains[M]"]
["SLC8A1",20.104153,1.643215,-3.612900394,0,0,"down","SLC8A1","solute carrier family 8 member A1","GO:0005432;GO:0005654;GO:0005886;GO:0005887;GO:0006816;GO:0006883;GO:0007154;GO:0008092;GO:0016020;GO:0016021;GO:0030501;GO:0030506;GO:0035725;GO:0035994;GO:0055085;GO:0070509;GO:0070588;GO:0098719;GO:0098735","K05849-ko04020 Calcium signaling pathway;ko04022 cGMP - PKG signaling pathway;ko04974 Protein digestion and absorption;ko04740 Olfactory transduction","-"]
["LOC107054034",5.971353,0.484772,-3.622679579,{"v":1.23e-26,"d":"1.23E-26"},{"v":4.07e-26,"d":"4.07E-26"},"down","LOC107054034","-","-","-","-"]
["TUBB3",11.544841,0.932731,-3.629643426,{"v":1.25e-70,"d":"1.25E-70"},{"v":6.78e-70,"d":"6.78E-70"},"down","TUBB3","tubulin beta 3 class III","-","K07375-ko04145 Phagosome;ko04540 Gap junction;ko05130 Pathogenic Escherichia coli infection","-"]
["SYNPO2",174.107651,14.031694,-3.633218506,0,0,"down","SYNPO2","-","GO:0001725;GO:0003779;GO:0005634;GO:0005829;GO:0005925;GO:0015629;GO:0030018;GO:0031005;GO:0032233;GO:0043231;GO:0051393","-","-"]
["CHRDL2",55.458382,4.43695,-3.643765326,0,0,"down","CHRDL2","-","-","-","-"]
["LRRC26",111.124512,8.860853,-3.648587685,0,0,"down","LRRC26","-","GO:0016020;GO:0016021","-","-"]
["SLC24A3",16.906036,1.341185,-3.655958269,0,0,"down","SLC24A3","-","GO:0005262;GO:0005509;GO:0005886;GO:0005887;GO:0006811;GO:0006874;GO:0008273;GO:0016020;GO:0016021;GO:0030955;GO:0031402;GO:0035725;GO:0055085;GO:0070588","-","KOG1307-K+-dependent Ca2+/Na+ exchanger NCKX1 and related proteins[PT]"]
["LOC768772",2929.600098,231.679092,-3.660503986,0,0,"down","LOC768772","-","-","-","-"]
["LOC415662",74.095345,5.859239,-3.660597705,{"v":9.93e-295,"d":"9.93E-295"},{"v":1.49e-293,"d":"1.49E-293"},"down","LOC415662","C-factor-like","-","-","-"]
["PPEF1",5.11473,0.398257,-3.682886459,{"v":1.7e-61,"d":"1.70E-61"},{"v":8.54e-61,"d":"8.54E-61"},"down","PPEF1","-","GO:0004721;GO:0005506;GO:0005509;GO:0006470;GO:0016787;GO:0030145;GO:0050906","-","KOG0377-Protein serine/threonine phosphatase RDGC/PPEF, contains STphosphatase and EF-hand domains[T]"]
["FOXG1",13.711723,1.066857,-3.683971153,{"v":8.28e-146,"d":"8.28E-146"},{"v":7.22e-145,"d":"7.22E-145"},"down","FOXG1","forkhead box G1","GO:0000981;GO:0003677;GO:0003700;GO:0005634;GO:0006351;GO:0006355;GO:0006357;GO:0007275;GO:0009653;GO:0030154;GO:0043565;GO:0045892","K09385-ko04068 FoxO signaling pathway","KOG3562-Forkhead/HNF-3-related transcription factor[K]"]
["RNF222",27.064991,2.10544,-3.68423424,{"v":2.27e-218,"d":"2.27E-218"},{"v":2.68e-217,"d":"2.68E-217"},"down","RNF222","-","GO:0016020;GO:0016021;GO:0016567;GO:0033234;GO:0033768;GO:0043161;GO:0046872;GO:0061630","-","-"]
["SLC35F2",7.374903,0.569981,-3.69363834,{"v":2.81e-54,"d":"2.81E-54"},{"v":1.32e-53,"d":"1.32E-53"},"down","SLC35F2","-","GO:0016020;GO:0016021;GO:0022857;GO:0055085","-","KOG2766-Predicted membrane protein[S]"]
["LOC107053414",721.291504,55.711449,-3.694536686,0,0,"down","LOC107053414","-","-","-","-"]
["LOC415661",372.666748,28.75621,-3.695940648,0,0,"down","LOC415661","-","GO:0000166","-","-"]
["MALL",356.049683,27.403307,-3.699656657,0,0,"down","MALL","mal, T-cell differentiation protein like","GO:0001766;GO:0008104;GO:0016020;GO:0016021;GO:0019911;GO:0042552;GO:0045121","-","-"]
["RRM2",20.929276,1.584039,-3.723842645,{"v":9.82e-189,"d":"9.82E-189"},{"v":1.03e-187,"d":"1.03E-187"},"down","RRM2","-","GO:0004748;GO:0005971;GO:0008199;GO:0009262;GO:0009263;GO:0016020;GO:0016021;GO:0016491;GO:0042803;GO:0051259;GO:0051290;GO:0055114","K10808-ko00230 Purine metabolism;ko00240 Pyrimidine metabolism;ko00480 Glutathione metabolism;ko04115 p53 signaling pathway","-"]
["TES",335.425476,25.371181,-3.724729686,0,0,"down","TES","testin LIM domain protein","GO:0005737;GO:0005829;GO:0005886;GO:0005925;GO:0008270;GO:0008285;GO:0030054;GO:0032991;GO:0042127;GO:0046872","-","KOG2272-Focal adhesion protein PINCH-1, contains LIM domains[TZ]"]
["LOC107055376",6.61566,0.496992,-3.734590557,{"v":1.02e-117,"d":"1.02E-117"},{"v":7.62e-117,"d":"7.62E-117"},"down","LOC107055376","-","-","-","-"]
["MMP27",22.969481,1.722243,-3.73735764,{"v":5.21e-164,"d":"5.21E-164"},{"v":4.94e-163,"d":"4.94E-163"},"down","MMP27","matrix metallopeptidase 27","GO:0004222;GO:0006508;GO:0008233;GO:0008237;GO:0008270;GO:0016787;GO:0031012;GO:0042406;GO:0046872","-","KOG1565-Gelatinase A and related matrix metalloproteases[OW]"]
["FRMD1",18.589466,1.364464,-3.768079092,0,0,"down","FRMD1","-","GO:0005200;GO:0005856;GO:0031032","-","-"]
["PKP3",88.547081,6.479618,-3.772464081,0,0,"down","PKP3","-","GO:0002159;GO:0005634;GO:0005654;GO:0005886;GO:0007155;GO:0010628;GO:0019899;GO:0030054;GO:0030057;GO:0045294;GO:0050839;GO:0072659;GO:0098609;GO:1902373;GO:1990124","-","-"]
["UPK1B",1363.374268,98.428818,-3.791957079,0,0,"down","UPK1B","-","GO:0005887;GO:0007166;GO:0009617;GO:0016020;GO:0016021;GO:0016324;GO:0030855;GO:0120001","-","KOG3882-Tetraspanin family integral membrane protein[R]"]
["C4ORF19",132.645157,9.51459,-3.801286703,0,0,"down","C4ORF19","-","-","-","-"]
["E2F7",5.173878,0.370598,-3.803319035,{"v":2.99e-140,"d":"2.99E-140"},{"v":2.52e-139,"d":"2.52E-139"},"down","E2F7","-","GO:0000122;GO:0000977;GO:0000978;GO:0000987;GO:0001227;GO:0002040;GO:0003677;GO:0003700;GO:0003714;GO:0005634;GO:0005667;GO:0006351;GO:0006355;GO:0008285;GO:0016607;GO:0030330;GO:0032466;GO:0032877;GO:0042802;GO:0045944;GO:0060718;GO:0070365;GO:0071930;GO:2000134","-","KOG2578-Transcription factor E2F/dimerization partner (TDP)-like proteins[K]"]
["ALDH1A2",42.481918,3.004452,-3.821675125,0,0,"down","ALDH1A2","aldehyde dehydrogenase 1 family member A2","GO:0001568;GO:0001758;GO:0001936;GO:0003007;GO:0004028;GO:0005737;GO:0008152;GO:0008284;GO:0008285;GO:0009855;GO:0009952;GO:0009954;GO:0010628;GO:0014032;GO:0016331;GO:0016491;GO:0016620;GO:0021915;GO:0030182;GO:0030324;GO:0030326;GO:0030900;GO:0030902;GO:0031016;GO:0031076;GO:0034097;GO:0035115;GO:0035799;GO:0042573;GO:0042574;GO:0042904;GO:0043010;GO:0043065;GO:0048384;GO:0048566;GO:0048738;GO:0055114;GO:0060324;GO:0071300;GO:0090242;GO:0001568;GO:0001758;GO:0001936;GO:0001947;GO:0003007;GO:0004028;GO:0004029;GO:0004745;GO:0005737;GO:0008152;GO:0008284;GO:0008285;GO:0009855;GO:0009952;GO:0009954;GO:0010628;GO:0014032;GO:0016331;GO:0016491;GO:0016620;GO:0021522;GO:0021915;GO:0030182;GO:0030324;GO:0030326;GO:0030900;GO:0030902;GO:0031016;GO:0031076;GO:0034097;GO:0035115;GO:0035799;GO:0042572;GO:0042573;GO:0042574;GO:0042904;GO:0043010;GO:0043065;GO:0048384;GO:0048566;GO:0048738;GO:0055114;GO:0060324;GO:0071300;GO:0090242","K07249-ko00830 Retinol metabolism","KOG2450-Aldehyde dehydrogenase[C]"]
["RBPMS2",156.449982,11.020275,-3.827469362,0,0,"down","RBPMS2","RNA binding protein with multiple splicing 2","GO:0000398;GO:0003676;GO:0003713;GO:0003723;GO:0003729;GO:0005685;GO:0005737;GO:0007275;GO:0008143;GO:0010862;GO:0030514;GO:0030619;GO:0035614;GO:0042803;GO:0048557;GO:0048565;GO:0048661;GO:0051151;GO:0060391;GO:1903508","-","KOG1457-RNA binding protein (contains RRM repeats)[R]"]
["NACAD",5.84255,0.410465,-3.831267061,{"v":1.41e-142,"d":"1.41E-142"},{"v":1.21e-141,"d":"1.21E-141"},"down","NACAD","-","-","-","-"]
["PTGR1",546.105164,38.273155,-3.834774061,0,0,"down","PTGR1","prostaglandin reductase 1","GO:0005737;GO:0016491;GO:0032440;GO:0047522;GO:0055114","-","KOG1196-Predicted NAD-dependent oxidoreductase[R]"]
["NPW",147.254349,10.279191,-3.840511613,0,0,"down","NPW","-","GO:0001664;GO:0007186;GO:0007218;GO:0007631","-","-"]
["SPDEF",198.11528,13.746273,-3.849227733,0,0,"down","SPDEF","-","GO:0000122;GO:0000981;GO:0003677;GO:0003700;GO:0005634;GO:0006355;GO:0006357;GO:0010454;GO:0010455;GO:0030154;GO:0043065;GO:0043565;GO:0045944;GO:0060480;GO:0060576","-","KOG3805-ERG and related ETS transcription factors[K]"]
["PRDM6",7.767822,0.529902,-3.873712664,{"v":1.77e-125,"d":"1.77E-125"},{"v":1.39e-124,"d":"1.39E-124"},"down","PRDM6","-","GO:0003676;GO:0005634;GO:0022008;GO:0042803;GO:0045892;GO:0051151","-","KOG2461-Transcription factor BLIMP-1/PRDI-BF1, contains C2H2-type Zn-finger and SET domains[K]"]
["TLR5",8.170009,0.554963,-3.879874174,{"v":2.45e-72,"d":"2.45E-72"},{"v":1.35e-71,"d":"1.35E-71"},"down","TLR5","toll like receptor 5","GO:0001819;GO:0002224;GO:0002376;GO:0002755;GO:0003725;GO:0004888;GO:0005886;GO:0005887;GO:0007165;GO:0016020;GO:0016021;GO:0034146;GO:0042742;GO:0043331;GO:0045087;GO:0050707;GO:0050725;GO:0051607","K10168-ko04620 Toll-like receptor signaling pathway;ko05321 Inflammatiory bowel disease (IBD);ko05130 Pathogenic Escherichia coli infection;ko05132 Salmonella infection;ko05134 Legionellosis","KOG4194-Membrane glycoprotein LIG-1[T]"]
["DSP",270.131714,18.239223,-3.888546849,0,0,"down","DSP","-","GO:0001533;GO:0002934;GO:0003223;GO:0005080;GO:0005198;GO:0005856;GO:0005882;GO:0005886;GO:0005911;GO:0014704;GO:0016323;GO:0018149;GO:0030054;GO:0030057;GO:0030216;GO:0030674;GO:0034332;GO:0043588;GO:0045104;GO:0045109;GO:0050839;GO:0071896;GO:0086073;GO:0086091;GO:0097110;GO:0098609;GO:0098911","-","KOG0516-Dystonin, GAS (Growth-arrest-specific protein), and related proteins[Z]"]
["ASPHD2",18.883211,1.264251,-3.900749284,{"v":1.71e-215,"d":"1.71E-215"},{"v":2e-214,"d":"2.00E-214"},"down","ASPHD2","-","GO:0004597;GO:0016020;GO:0016021;GO:0018193;GO:0042264;GO:0055114","-","KOG3696-Aspartyl beta-hydroxylase[O]"]
["GAL",65.072289,4.300172,-3.919577032,{"v":8.2e-230,"d":"8.20E-230"},{"v":1.01e-228,"d":"1.01E-228"},"down","GAL","galanin and GMAP prepropeptide","GO:0005179;GO:0005576;GO:0007218;GO:0010469;GO:0004966;GO:0005179;GO:0005184;GO:0005576;GO:0005615;GO:0005622;GO:0007218;GO:0007399;GO:0010469;GO:0010737;GO:0019933;GO:0031764;GO:0031765;GO:0031766;GO:0043025;GO:0045944;GO:0051464;GO:0051795;GO:1902608;GO:1902891","K05244-ko04080 Neuroactive ligand-receptor interaction","-"]
["KCNF1",23.837868,1.563751,-3.930172498,0,0,"down","KCNF1","-","GO:0005216;GO:0005244;GO:0005249;GO:0005267;GO:0006811;GO:0006813;GO:0008076;GO:0016020;GO:0016021;GO:0034765;GO:0051260;GO:0055085;GO:0071805","-","KOG3713-Voltage-gated K+ channel KCNB/KCNC[P]"]
["CSRP1",1954.952271,128.121857,-3.931544866,0,0,"down","CSRP1","cysteine and glycine rich protein 1","GO:0001725;GO:0005623;GO:0005634;GO:0005737;GO:0005856;GO:0005925;GO:0031252;GO:0046872;GO:0051219;GO:0051393","-","KOG1700-Regulatory protein MLP and related LIM proteins[TZ]"]
["LOC100857467",163.096085,10.64708,-3.937192426,0,0,"down","LOC100857467","-","-","-","-"]
["PACSIN1",12.484666,0.812543,-3.941569253,{"v":3.43e-144,"d":"3.43E-144"},{"v":2.97e-143,"d":"2.97E-143"},"down","PACSIN1","-","GO:0005543;GO:0005737;GO:0005768;GO:0007015;GO:0030100;GO:0048666;GO:0048812;GO:0097320","-","KOG2856-Adaptor protein PACSIN[TUZ]"]
["SLC35F3",7.087097,0.45631,-3.957108619,{"v":2.69e-93,"d":"2.69E-93"},{"v":1.73e-92,"d":"1.73E-92"},"down","SLC35F3","-","GO:0015888;GO:0016020;GO:0016021","-","KOG4314-Predicted carbohydrate/phosphate translocator[R]"]
["RIMS1",32.365276,2.07569,-3.962783905,0,0,"down","RIMS1","-","GO:0005622;GO:0006886;GO:0006887;GO:0016020;GO:0017137;GO:0042391;GO:0044325;GO:0046872;GO:0048786;GO:0048791;GO:0065003;GO:1903861;GO:2000300","-","-"]
["ALDH3B1L1",52.610813,3.297304,-3.996000535,0,0,"down","ALDH3B1L1","-","-","K00129-ko00010 Glycolysis / Gluconeogenesis;ko00340 Histidine metabolism;ko00350 Tyrosine metabolism;ko00360 Phenylalanine metabolism;ko00410 beta-Alanine metabolism;ko00980 Metabolism of xenobiotics by cytochrome P450;ko00982 Drug metabolism - cytochrome P450;ko05204 Chemical carcinogenesis","-"]
["TFAP2C",27.203749,1.681348,-4.016115221,0,0,"down","TFAP2C","-","GO:0000122;GO:0000977;GO:0000978;GO:0000981;GO:0003677;GO:0003700;GO:0005634;GO:0005654;GO:0005739;GO:0006355;GO:0006366;GO:0008584;GO:0040029;GO:0042127;GO:0045944;GO:0046983;GO:0048856","-","KOG3811-Transcription factor AP-2[K]"]
["FGF22",19.997467,1.228279,-4.025107064,{"v":4.4e-142,"d":"4.40E-142"},{"v":3.76e-141,"d":"3.76E-141"},"down","FGF22","-","GO:0005104;GO:0005576;GO:0005730;GO:0005794;GO:0008083;GO:0008543;GO:0009986;GO:0010469","K04358-ko04014 Ras signaling pathway;ko04015 Rap1 signaling pathway;ko04010 MAPK signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04810 Regulation of actin cytoskeleton;ko05200 Pathways in cancer;ko05218 Melanoma;ko05224 Breast cancer","KOG3885-Fibroblast growth factor[T]"]
["FAM129A",198.056107,12.152535,-4.026579993,0,0,"down","FAM129A","family with sequence similarity 129 member A","GO:0001933;GO:0001934;GO:0005737;GO:0005829;GO:0005886;GO:0034976;GO:0045727","-","-"]
["ST6GALNAC2",31.100021,1.889249,-4.04103079,{"v":1.81e-276,"d":"1.81E-276"},{"v":2.56e-275,"d":"2.56E-275"},"down","ST6GALNAC2","ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2","GO:0001665;GO:0005794;GO:0006486;GO:0006493;GO:0008373;GO:0016020;GO:0016021;GO:0016740;GO:0016757;GO:1990743;GO:0000139;GO:0001665;GO:0005794;GO:0006486;GO:0006493;GO:0008373;GO:0009311;GO:0016020;GO:0016021;GO:0016740;GO:0016757;GO:0018279;GO:0097503;GO:1990743","-","KOG2692-Sialyltransferase[G]"]
["CLDN10",407.315186,24.70088,-4.043511258,0,0,"down","CLDN10","claudin 10","GO:0005198;GO:0005737;GO:0005886;GO:0005923;GO:0016020;GO:0016021;GO:0030054;GO:0043269","K06087-ko04514 Cell adhesion molecules (CAMs);ko04530 Tight junction;ko04670 Leukocyte transendothelial migration;ko05160 Hepatitis C","-"]
["SGPP2",6.782298,0.410689,-4.045655963,{"v":1.66e-224,"d":"1.66E-224"},{"v":2e-223,"d":"2.00E-223"},"down","SGPP2","-","GO:0005783;GO:0006670;GO:0016020;GO:0016021;GO:0016311;GO:0042392","K04717-ko00600 Sphingolipid metabolism;ko04071 Sphingolipid signaling pathway","KOG2822-Sphingoid base-phosphate phosphatase[I]"]
["INA",16.394724,0.978822,-4.066041277,{"v":1.59e-176,"d":"1.59E-176"},{"v":1.59e-175,"d":"1.59E-175"},"down","INA","-","GO:0005198;GO:0005882;GO:0005883;GO:0061564","-","KOG0977-Nuclear envelope protein lamin, intermediate filament superfamily[DY]"]
["PHGDH",15.76601,0.937216,-4.072292201,{"v":4.41e-134,"d":"4.41E-134"},{"v":3.63e-133,"d":"3.63E-133"},"down","PHGDH","-","GO:0004617;GO:0006541;GO:0006544;GO:0006563;GO:0006564;GO:0006566;GO:0008152;GO:0008652;GO:0009448;GO:0010468;GO:0016491;GO:0016616;GO:0019530;GO:0021510;GO:0021782;GO:0021915;GO:0022008;GO:0031175;GO:0043209;GO:0051287;GO:0055114;GO:0070314","K00058-ko01200 Carbon metabolism;ko01230 Biosynthesis of amino acids;ko00680 Methane metabolism;ko00260 Glycine, serine and threonine metabolism","-"]
["GNG4",37.909637,2.248349,-4.075626742,{"v":1.37e-179,"d":"1.37E-179"},{"v":1.39e-178,"d":"1.39E-178"},"down","GNG4","-","GO:0003924;GO:0005834;GO:0005886;GO:0007165;GO:0007186;GO:0016020;GO:0030308","K04541-ko04014 Ras signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04062 Chemokine signaling pathway;ko04724 Glutamatergic synapse;ko04727 GABAergic synapse;ko04725 Cholinergic synapse;ko04728 Dopaminergic synapse;ko04726 Serotonergic synapse;ko04723 Retrograde endocannabinoid signaling;ko04713 Circadian entrainment;ko05200 Pathways in cancer;ko05032 Morphine addiction;ko05034 Alcoholism","KOG4119-G protein gamma subunit[T]"]
["C6orf132",121.636162,7.21372,-4.075684964,0,0,"down","C6orf132","-","-","-","-"]
["LOC101748744",32.992886,1.955276,-4.076710808,0,0,"down","LOC101748744","-","GO:0004252;GO:0006508;GO:0008233;GO:0008236;GO:0016787","-","-"]
["FBP1",89.312599,5.243016,-4.090394852,0,0,"down","FBP1","fructose-bisphosphatase 1","GO:0000122;GO:0001191;GO:0005634;GO:0005737;GO:0005829;GO:0005975;GO:0005986;GO:0006000;GO:0006002;GO:0006094;GO:0006111;GO:0016208;GO:0016311;GO:0016787;GO:0016791;GO:0030308;GO:0030388;GO:0035690;GO:0042132;GO:0042578;GO:0042802;GO:0045820;GO:0046580;GO:0046872;GO:0051289;GO:0071286","K03841-ko01200 Carbon metabolism;ko00010 Glycolysis / Gluconeogenesis;ko00030 Pentose phosphate pathway;ko00051 Fructose and mannose metabolism;ko00710 Carbon fixation in photosynthetic organisms;ko00680 Methane metabolism;ko04152 AMPK signaling pathway;ko04910 Insulin signaling pathway","KOG1458-Fructose-1,6-bisphosphatase[G]"]
["LOC112532916",10.225134,0.597686,-4.09658819,{"v":1.46e-39,"d":"1.46E-39"},{"v":5.83e-39,"d":"5.83E-39"},"down","LOC112532916","-","-","-","-"]
["LOC107050543",5.396892,0.313083,-4.107511738,{"v":1.44e-53,"d":"1.44E-53"},{"v":6.7e-53,"d":"6.70E-53"},"down","LOC107050543","-","-","-","-"]
["SLC5A1",40.514885,2.339862,-4.113956695,0,0,"down","SLC5A1","solute carrier family 5 member 1","GO:0005412;GO:0005887;GO:0006814;GO:0016020;GO:0016021;GO:0022857;GO:0055085;GO:1904659","-","KOG2349-Na+:iodide/myo-inositol/multivitamin symporters[P]"]
["LOC101749287",38.231106,2.204677,-4.116107725,0,0,"down","LOC101749287","-","-","-","-"]
["ANXA8",1682.915527,97.006233,-4.116741504,0,0,"down","ANXA8","-","GO:0005509;GO:0005544","-","-"]
["NEFL",7.510215,0.429621,-4.12771779,{"v":4.14e-78,"d":"4.14E-78"},{"v":2.37e-77,"d":"2.37E-77"},"down","NEFL","-","GO:0000226;GO:0005198;GO:0005200;GO:0005737;GO:0005882;GO:0005883;GO:0008022;GO:0008089;GO:0008090;GO:0014012;GO:0019896;GO:0030424;GO:0030674;GO:0031133;GO:0031594;GO:0033596;GO:0033693;GO:0040011;GO:0042802;GO:0043005;GO:0043209;GO:0043524;GO:0045109;GO:0045110;GO:0048812;GO:0050772;GO:0050885;GO:0060052;GO:0060074;GO:0061564;GO:0098685;GO:0098981;GO:0099160;GO:0099182;GO:0099184;GO:0099185;GO:1904115","-","KOG0977-Nuclear envelope protein lamin, intermediate filament superfamily[DY]"]
["KCNG1",20.377466,1.16211,-4.13215612,0,0,"down","KCNG1","-","GO:0005216;GO:0005244;GO:0005249;GO:0005251;GO:0005267;GO:0005886;GO:0006811;GO:0006813;GO:0008076;GO:0016020;GO:0016021;GO:0034765;GO:0051260;GO:0055085;GO:0071805","-","KOG3713-Voltage-gated K+ channel KCNB/KCNC[P]"]
["FAM132A",7.802569,0.444139,-4.134866045,{"v":4.5e-112,"d":"4.50E-112"},{"v":3.26e-111,"d":"3.26E-111"},"down","FAM132A","-","GO:0005179;GO:0005576;GO:0005615;GO:0010469;GO:0010906;GO:0035774;GO:0045721;GO:0046324;GO:0046326;GO:0046628;GO:0050728;GO:0051897","-","-"]
["SLC6A14",39.960545,2.262563,-4.14254639,0,0,"down","SLC6A14","-","GO:0005215;GO:0005328;GO:0005887;GO:0006520;GO:0006836;GO:0009636;GO:0015293;GO:0016020;GO:0016021;GO:0055085","-","-"]
["PI15",21.278387,1.204209,-4.143231082,{"v":5.78e-139,"d":"5.78E-139"},{"v":4.85e-138,"d":"4.85E-138"},"down","PI15","peptidase inhibitor 15","GO:0005576;GO:0007275;GO:0010466;GO:0030414","-","KOG3017-Defense-related protein containing SCP domain[S]"]
["LOC771917",27.889574,1.573422,-4.147748332,{"v":1.43e-291,"d":"1.43E-291"},{"v":2.12e-290,"d":"2.12E-290"},"down","LOC771917","-","GO:0016020;GO:0016021","-","-"]
["KRT80",15.999368,0.900375,-4.151345108,0,0,"down","KRT80","-","GO:0005198;GO:0005882;GO:0045095;GO:0045111","-","KOG0977-Nuclear envelope protein lamin, intermediate filament superfamily[DY]"]
["LOC107049164",45.257809,2.492156,-4.182700459,{"v":4.27e-203,"d":"4.27E-203"},{"v":4.78e-202,"d":"4.78E-202"},"down","LOC107049164","-","-","-","-"]
["CRABP2",20.272921,1.092148,-4.214313695,{"v":4.74e-118,"d":"4.74E-118"},{"v":3.56e-117,"d":"3.56E-117"},"down","CRABP2","-","GO:0001972;GO:0005634;GO:0005654;GO:0005737;GO:0005783;GO:0005829;GO:0008289;GO:0016918;GO:0019841;GO:0035115;GO:0042573;GO:0048385;GO:0048672","-","KOG4015-Fatty acid-binding protein FABP[I]"]
["SMOC1",16.075331,0.853153,-4.235900143,{"v":3.68e-291,"d":"3.68E-291"},{"v":5.44e-290,"d":"5.44E-290"},"down","SMOC1","-","GO:0001654;GO:0005509;GO:0045667;GO:0050840;GO:0060173","-","KOG4578-Uncharacterized conserved protein, contains KAZAL and TY domains[R]"]
["PAQR8",52.19614,2.743679,-4.249759514,0,0,"down","PAQR8","progestin and adipoQ receptor family member 8","GO:0003707;GO:0005496;GO:0005794;GO:0005886;GO:0016020;GO:0016021;GO:0043401;GO:0048545","-","KOG0748-Predicted membrane proteins, contain hemolysin III domain[RT]"]
["ADH1C",212.657379,11.104997,-4.259250008,0,0,"down","ADH1C","alcohol dehydrogenase 1C (class I), gamma polypeptide","GO:0008270;GO:0016491;GO:0046872;GO:0055114","K13951-ko00010 Glycolysis / Gluconeogenesis;ko00071 Fatty acid degradation;ko00350 Tyrosine metabolism;ko00830 Retinol metabolism;ko00980 Metabolism of xenobiotics by cytochrome P450;ko00982 Drug metabolism - cytochrome P450;ko05204 Chemical carcinogenesis","KOG0022-Alcohol dehydrogenase, class III[Q]"]
["SERPINB12",78.745193,4.109069,-4.260308395,0,0,"down","SERPINB12","-","GO:0004867;GO:0005615;GO:0010951","-","-"]
["MGAT3",32.114704,1.644456,-4.287551687,0,0,"down","MGAT3","mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase","GO:0003830;GO:0006487;GO:0016020","K00737-ko00510 N-Glycan biosynthesis","-"]
["ASCL1",17.784241,0.909286,-4.289721454,{"v":1.92e-168,"d":"1.92E-168"},{"v":1.86e-167,"d":"1.86E-167"},"down","ASCL1","achaete-scute family bHLH transcription factor 1","GO:0000122;GO:0000978;GO:0001764;GO:0003358;GO:0003359;GO:0003677;GO:0003682;GO:0003700;GO:0005634;GO:0006357;GO:0007219;GO:0007346;GO:0007389;GO:0007399;GO:0007400;GO:0007405;GO:0008593;GO:0010001;GO:0010468;GO:0014003;GO:0021527;GO:0021529;GO:0021530;GO:0021750;GO:0021779;GO:0021892;GO:0021902;GO:0021954;GO:0021987;GO:0022008;GO:0030154;GO:0030182;GO:0030856;GO:0032526;GO:0042127;GO:0043025;GO:0043066;GO:0043425;GO:0043525;GO:0043565;GO:0045665;GO:0045747;GO:0045787;GO:0045892;GO:0045944;GO:0046983;GO:0048469;GO:0048663;GO:0048665;GO:0048666;GO:0048699;GO:0048709;GO:0050767;GO:0050769;GO:0050883;GO:0060163;GO:0060165;GO:0060166;GO:0060579;GO:0061100;GO:0061102;GO:0061103;GO:0061104;GO:0061549;GO:0070888;GO:2000179","-","KOG4029-Transcription factor HAND2/Transcription factor TAL1/TAL2/LYL1[K]"]
["SPTLC3",18.42997,0.933271,-4.303613846,{"v":3.41e-257,"d":"3.41E-257"},{"v":4.58e-256,"d":"4.58E-256"},"down","SPTLC3","-","GO:0003824;GO:0004758;GO:0008152;GO:0009058;GO:0016020;GO:0016021;GO:0016740;GO:0017059;GO:0030170;GO:0046520","K00654-ko00600 Sphingolipid metabolism;ko04071 Sphingolipid signaling pathway","KOG1357-Serine palmitoyltransferase[O]"]
["TAGLN",4859.893555,241.239395,-4.332387288,0,0,"down","TAGLN","transgelin","GO:0005737;GO:0030855;GO:0051015","-","KOG2046-Calponin[Z]"]
["TAGAP",38.506454,1.90974,-4.333652131,0,0,"down","TAGAP","-","GO:0007165","-","KOG4724-Predicted Rho GTPase-activating protein[T]"]
["LOC107054623",53.011616,2.609493,-4.344467083,0,0,"down","LOC107054623","-","-","-","-"]
["PERP1",343.665497,16.819172,-4.352826427,0,0,"down","PERP1","PERP1, TP53 apoptosis effector","GO:0016020;GO:0016021","K10136-ko04115 p53 signaling pathway","KOG4671-Brain cell membrane protein 1 (BCMP1)[R]"]
["LOC425623",15.551518,0.753822,-4.3666877,{"v":1.09e-212,"d":"1.09E-212"},{"v":1.27e-211,"d":"1.27E-211"},"down","LOC425623","-","-","-","-"]
["FUT6",49.723782,2.396123,-4.375162159,0,0,"down","FUT6","-","GO:0000139;GO:0005794;GO:0006486;GO:0008417;GO:0016020;GO:0016021;GO:0016740;GO:0016757;GO:0032580;GO:0036065;GO:0046920","K00716-ko00601 Glycosphingolipid biosynthesis - lacto and neolacto series","-"]
["EFNA2",21.104813,1.010481,-4.384457946,{"v":2.35e-71,"d":"2.35E-71"},{"v":1.28e-70,"d":"1.28E-70"},"down","EFNA2","ephrin A2","GO:0005886;GO:0007411;GO:0016020;GO:0030316;GO:0031225;GO:0046849;GO:0046875;GO:0048013;GO:0016020;GO:0030316;GO:0046849;GO:0046875;GO:0048013","K05462-ko04014 Ras signaling pathway;ko04015 Rap1 signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04360 Axon guidance","KOG3858-Ephrin, ligand for Eph receptor tyrosine kinase[T]"]
["EDKM",46.096226,2.195274,-4.392175715,0,0,"down","EDKM","epidermal differentiation protein containing a KKLIQQ motif","-","-","-"]
["POF1B",609.972534,28.991158,-4.395059417,0,0,"down","POF1B","-","GO:0003382;GO:0005884;GO:0005912;GO:0005923;GO:0007015;GO:0030036;GO:0030057;GO:0051015;GO:0070830","-","-"]
["AIM1",223.276459,10.390158,-4.425541651,0,0,"down","AIM1","-","-","-","-"]
["LOC423301",5.201245,0.239281,-4.442079246,{"v":4.85e-71,"d":"4.85E-71"},{"v":2.64e-70,"d":"2.64E-70"},"down","LOC423301","-","-","-","-"]
["SCEL",139.786255,6.391025,-4.451031368,0,0,"down","SCEL","-","GO:0046872","-","-"]
["VSNL1",10.217539,0.464326,-4.459765873,{"v":1.17e-58,"d":"1.17E-58"},{"v":5.75e-58,"d":"5.75E-58"},"down","VSNL1","visinin like 1","GO:0005509;GO:0005829;GO:0016020;GO:0035774;GO:0045921;GO:0046676;GO:0046872","-","KOG0044-Ca2+ sensor (EF-Hand superfamily)[T]"]
["RYR2",9.05315,0.411196,-4.460521723,0,0,"down","RYR2","-","GO:0001666;GO:0002027;GO:0003143;GO:0003220;GO:0003300;GO:0005216;GO:0005219;GO:0005262;GO:0005509;GO:0005513;GO:0005515;GO:0005516;GO:0005790;GO:0005886;GO:0006811;GO:0006816;GO:0006874;GO:0008144;GO:0010460;GO:0010881;GO:0010882;GO:0014808;GO:0014850;GO:0015278;GO:0016020;GO:0016021;GO:0016529;GO:0019722;GO:0019899;GO:0019901;GO:0030017;GO:0030018;GO:0030509;GO:0031000;GO:0032991;GO:0033017;GO:0034236;GO:0034237;GO:0034704;GO:0035584;GO:0035994;GO:0042802;GO:0043231;GO:0043621;GO:0043924;GO:0048763;GO:0051209;GO:0051284;GO:0051775;GO:0055085;GO:0055117;GO:0060048;GO:0060070;GO:0060401;GO:0060402;GO:0070588;GO:0071313;GO:0071872;GO:0072599;GO:0086005;GO:0086029;GO:0097050;GO:0097159;GO:0098735;GO:0098904;GO:0098907;GO:0098910;GO:0098911;GO:1901896","K04962-ko04020 Calcium signaling pathway;ko04024 cAMP signaling pathway;ko04911 Insulin secretion;ko04921 Oxytocin signaling pathway;ko04260 Cardiac muscle contraction;ko04261 Adrenergic signaling in cardiomyocytes;ko04972 Pancreatic secretion;ko04713 Circadian entrainment;ko05410 Hypertrophic cardiomyopathy (HCM);ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC);ko05414 Dilated cardiomyopathy (DCM)","KOG2243-Ca2+ release channel (ryanodine receptor)[T]"]
["PRUNE2",25.063192,1.12721,-4.474741944,0,0,"down","PRUNE2","-","-","-","KOG4129-Exopolyphosphatases and related proteins[C]"]
["MIXL1",37.299366,1.676966,-4.475225764,{"v":2.54e-167,"d":"2.54E-167"},{"v":2.44e-166,"d":"2.44E-166"},"down","MIXL1","Mix paired-like homeobox","GO:0003677;GO:0005634;GO:0006355;GO:0043565","-","-"]
["MSLN",249.885712,11.226714,-4.476260788,0,0,"down","MSLN","-","GO:0007160;GO:0009986","-","-"]
["MYLK",574.563232,25.296944,-4.505430658,0,0,"down","MYLK","myosin light chain kinase","GO:0001725;GO:0004672;GO:0004687;GO:0005524;GO:0005737;GO:0005886;GO:0006468;GO:0006939;GO:0015629;GO:0016301;GO:0016310;GO:0030027;GO:0030335;GO:0032060;GO:0032154;GO:0051928;GO:0060414;GO:0071476;GO:0090303","K00907-ko04020 Calcium signaling pathway;ko04022 cGMP - PKG signaling pathway;ko04810 Regulation of actin cytoskeleton;ko04510 Focal adhesion;ko04611 Platelet activation;ko04921 Oxytocin signaling pathway;ko04270 Vascular smooth muscle contraction;ko04971 Gastric acid secretion","KOG0032-Ca2+/calmodulin-dependent protein kinase, EF-Hand protein superfamily[T]"]
["WNT10A",34.327019,1.50109,-4.515262194,{"v":5.6e-204,"d":"5.60E-204"},{"v":6.3e-203,"d":"6.30E-203"},"down","WNT10A","Wnt family member 10A","-","K01357-ko04310 Wnt signaling pathway;ko04390 Hippo signaling pathway;ko04150 mTOR signaling pathway;ko04550 Signaling pathways regulating pluripotency of stem cells;ko04916 Melanogenesis;ko05200 Pathways in cancer;ko05205 Proteoglycans in cancer;ko05217 Basal cell carcinoma;ko05224 Breast cancer;ko05166 HTLV-I infection","KOG3913-Wnt family of developmental regulators[T]"]
["KRT23",119.167183,5.164575,-4.528193549,0,0,"down","KRT23","-","GO:0005198;GO:0005882","-","KOG0977-Nuclear envelope protein lamin, intermediate filament superfamily[DY]"]
["ST8SIA1",36.880806,1.567887,-4.555976694,{"v":8.75e-231,"d":"8.75E-231"},{"v":1.08e-229,"d":"1.08E-229"},"down","ST8SIA1","ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1","-","K03371-ko00601 Glycosphingolipid biosynthesis - lacto and neolacto series;ko00603 Glycosphingolipid biosynthesis - globo series;ko00604 Glycosphingolipid biosynthesis - ganglio series","KOG2692-Sialyltransferase[G]"]
["LY6CLEL",2245.862549,94.440392,-4.571721795,0,0,"down","LY6CLEL","-","-","-","-"]
["TMEM40L",36.838306,1.545713,-4.574862344,0,0,"down","TMEM40L","-","-","-","-"]
["LOC100857820",112.110008,4.6619,-4.587853204,0,0,"down","LOC100857820","-","-","-","-"]
["PITX1",275.871948,11.2471,-4.6163738,0,0,"down","PITX1","paired-like homeodomain 1","GO:0003677;GO:0003700;GO:0005634;GO:0006355;GO:0007275;GO:0043565;GO:0003677;GO:0003700;GO:0005634;GO:0006351;GO:0006355;GO:0007275;GO:0043565","-","KOG0486-Transcription factor PTX1, contains HOX domain[K]"]
["S100A16",662.83075,26.820374,-4.627239273,0,0,"down","S100A16","-","GO:0005509;GO:0005615;GO:0005634;GO:0005730;GO:0005737;GO:0005829;GO:0005886;GO:0042803;GO:0046872;GO:0051592","-","-"]
["ANXA1",3981.383057,160.045029,-4.63671991,0,0,"down","ANXA1","annexin A1","GO:0001891;GO:0002250;GO:0002376;GO:0002548;GO:0002685;GO:0004859;GO:0005509;GO:0005544;GO:0005576;GO:0005615;GO:0005634;GO:0005737;GO:0005768;GO:0005769;GO:0005886;GO:0005929;GO:0006909;GO:0006954;GO:0007187;GO:0008360;GO:0010008;GO:0016020;GO:0016323;GO:0016324;GO:0016328;GO:0019834;GO:0030659;GO:0031232;GO:0031313;GO:0031410;GO:0031514;GO:0031532;GO:0031901;GO:0032652;GO:0032743;GO:0042102;GO:0042995;GO:0043086;GO:0045087;GO:0045627;GO:0045629;GO:0045920;GO:0046872;GO:0046883;GO:0050727;GO:0070062;GO:0071385;GO:0071621;GO:0090303;GO:0001533;GO:0001780;GO:0002548;GO:0002685;GO:0004859;GO:0005198;GO:0005509;GO:0005544;GO:0005615;GO:0005634;GO:0005654;GO:0005737;GO:0005768;GO:0005829;GO:0005884;GO:0005886;GO:0006909;GO:0006954;GO:0007165;GO:0007187;GO:0008360;GO:0009986;GO:0014839;GO:0016324;GO:0016328;GO:0018149;GO:0019834;GO:0019898;GO:0030216;GO:0030674;GO:0031232;GO:0031340;GO:0031514;GO:0031532;GO:0032652;GO:0032743;GO:0033031;GO:0035924;GO:0042102;GO:0042127;GO:0042383;GO:0043086;GO:0045627;GO:0045629;GO:0045920;GO:0046632;GO:0046883;GO:0048306;GO:0050482;GO:0050727;GO:0070062;GO:0071385;GO:0071621;GO:0090050;GO:0090303;GO:0097350;GO:1900087;GO:2000483","-","KOG0819-Annexin[U]"]
["TMPRSS11D",11.304156,0.441754,-4.677466272,0,0,"down","TMPRSS11D","-","-","-","-"]
["NKX3-1",246.302628,9.457364,-4.702850086,0,0,"down","NKX3-1","-","-","-","-"]
["FTCD",498.252411,18.881685,-4.721817365,0,0,"down","FTCD","formimidoyltransferase cyclodeaminase","GO:0000139;GO:0003824;GO:0005542;GO:0005737;GO:0005794;GO:0005814;GO:0005829;GO:0005856;GO:0005886;GO:0006547;GO:0008017;GO:0008152;GO:0016740;GO:0016829;GO:0019556;GO:0019557;GO:0030409;GO:0030412;GO:0030868;GO:0035999;GO:0044237","K13990-ko00340 Histidine metabolism;ko00670 One carbon pool by folate","-"]
["MSMB",5165.094238,194.558731,-4.730517042,0,0,"down","MSMB","-","-","-","-"]
["CBLN4",5.714691,0.214976,-4.732427981,{"v":1.75e-56,"d":"1.75E-56"},{"v":8.46e-56,"d":"8.46E-56"},"down","CBLN4","cerebellin 4 precursor","GO:0005615;GO:0009306","-","-"]
["LOC101747680",146.910492,5.505671,-4.737875221,0,0,"down","LOC101747680","C-factor-like","-","-","-"]
["LOC101750376",112.363472,4.191329,-4.744621528,{"v":3.32e-211,"d":"3.32E-211"},{"v":3.82e-210,"d":"3.82E-210"},"down","LOC101750376","-","-","-","-"]
["LOC107053667",9.154457,0.337268,-4.762506968,{"v":4.77e-275,"d":"4.77E-275"},{"v":6.72e-274,"d":"6.72E-274"},"down","LOC107053667","-","-","-","-"]
["LOC107054158",5.409967,0.199015,-4.764670716,{"v":2.88e-75,"d":"2.88E-75"},{"v":1.62e-74,"d":"1.62E-74"},"down","LOC107054158","-","-","-","-"]
["KCNMB1",167.525436,6.138263,-4.770405891,0,0,"down","KCNMB1","potassium calcium-activated channel subfamily M regulatory beta subunit 1","GO:0006813;GO:0015269;GO:0016020;GO:0016021;GO:0071805","K04937-ko04022 cGMP - PKG signaling pathway;ko04911 Insulin secretion;ko04270 Vascular smooth muscle contraction","-"]
["ST6GALNAC1",36.023796,1.315298,-4.775488608,0,0,"down","ST6GALNAC1","ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1","GO:0000139;GO:0001574;GO:0001665;GO:0005794;GO:0006486;GO:0008373;GO:0009311;GO:0009312;GO:0016020;GO:0016021;GO:0016740;GO:0016757;GO:0018279;GO:0097503","K03479-ko00512 Mucin type O-glycan biosynthesis","KOG2692-Sialyltransferase[G]"]
["BPIL",7.700197,0.279859,-4.782123307,{"v":1.72e-76,"d":"1.72E-76"},{"v":9.76e-76,"d":"9.76E-76"},"down","BPIL","-","GO:0001530;GO:0006955;GO:0008289;GO:0050829","-","-"]
["CAPN14",81.488846,2.875597,-4.824669191,0,0,"down","CAPN14","-","GO:0004198;GO:0005509;GO:0005622;GO:0005737;GO:0006508;GO:0008233;GO:0008234;GO:0016787","-","KOG0045-Cytosolic Ca2+-dependent cysteine protease (calpain), large subunit (EF-Hand protein superfamily)[OT]"]
["SPIK5",22156.2832,774.356995,-4.838573241,0,0,"down","SPIK5","serine peptidase inhibitor, Kazal type 5","-","-","-"]
["PCK1",9.03384,0.315266,-4.840697867,{"v":9.37e-132,"d":"9.37E-132"},{"v":7.62e-131,"d":"7.62E-131"},"down","PCK1","phosphoenolpyruvate carboxykinase 1","GO:0000166;GO:0000287;GO:0003729;GO:0004550;GO:0004611;GO:0004613;GO:0005525;GO:0005737;GO:0005829;GO:0006006;GO:0006089;GO:0006090;GO:0006094;GO:0006111;GO:0006165;GO:0006475;GO:0006522;GO:0006531;GO:0006536;GO:0006541;GO:0006544;GO:0006560;GO:0006629;GO:0006735;GO:0007296;GO:0007568;GO:0007586;GO:0008343;GO:0008906;GO:0009069;GO:0009792;GO:0015701;GO:0015743;GO:0016042;GO:0016310;GO:0016829;GO:0016831;GO:0017076;GO:0018984;GO:0018991;GO:0019157;GO:0019543;GO:0019563;GO:0019904;GO:0019953;GO:0030145;GO:0030703;GO:0031406;GO:0032496;GO:0032868;GO:0032869;GO:0033993;GO:0042149;GO:0042594;GO:0043565;GO:0043950;GO:0045722;GO:0045912;GO:0045913;GO:0046015;GO:0046327;GO:0046872;GO:0046898;GO:0047134;GO:0048562;GO:0048589;GO:0050692;GO:0050892;GO:0051365;GO:0051379;GO:0051384;GO:0051591;GO:0060259;GO:0061402;GO:0070365;GO:0070741;GO:0071300;GO:0071320;GO:0071332;GO:0071333;GO:0071347;GO:0071356;GO:0071361;GO:0071374;GO:0071377;GO:0071456;GO:0071549;GO:0072071;GO:1904640","K01596-ko00010 Glycolysis / Gluconeogenesis;ko00020 Citrate cycle (TCA cycle);ko00620 Pyruvate metabolism;ko04068 FoxO signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04152 AMPK signaling pathway;ko04910 Insulin signaling pathway;ko04922 Glucagon signaling pathway;ko04920 Adipocytokine signaling pathway;ko03320 PPAR signaling pathway;ko04964 Proximal tubule bicarbonate reclamation;ko04931 Insulin resistance","KOG3749-Phosphoenolpyruvate carboxykinase[C]"]
["TMPRSS2",54.303898,1.891814,-4.843213603,0,0,"down","TMPRSS2","-","GO:0004252;GO:0005044;GO:0005886;GO:0006508;GO:0006898;GO:0008233;GO:0008236;GO:0016020;GO:0016540;GO:0016787;GO:0046598","K09633-ko05202 Transcriptional misregulation in cancers;ko05164 Influenza A","KOG3627-Trypsin[E]"]
["MUC",38.979961,1.318538,-4.885721592,{"v":1.15e-167,"d":"1.15E-167"},{"v":1.11e-166,"d":"1.11E-166"},"down","MUC","-","-","-","-"]
["CDH6",6.48952,0.217259,-4.900623925,{"v":2.94e-276,"d":"2.94E-276"},{"v":4.15e-275,"d":"4.15E-275"},"down","CDH6","cadherin 6","GO:0005509;GO:0005623;GO:0005886;GO:0007155;GO:0007156;GO:0007219;GO:0016020;GO:0016021;GO:0046872","-","KOG4289-Cadherin EGF LAG seven-pass G-type receptor[T]"]
["P2RY14",45.792953,1.467155,-4.964032401,0,0,"down","P2RY14","purinergic receptor P2Y, G-protein coupled, 14","GO:0004930;GO:0007186;GO:0016020;GO:0016021;GO:0035589;GO:0045028","K04299-ko04080 Neuroactive ligand-receptor interaction","KOG4219-G protein-coupled receptor[T]"]
["ADORA1",40.639603,1.278668,-4.99017268,0,0,"down","ADORA1","adenosine A1 receptor","GO:0001609;GO:0001973;GO:0002686;GO:0003093;GO:0004930;GO:0005886;GO:0007165;GO:0007186;GO:0016020;GO:0016021;GO:0043197;GO:0045202;GO:0050728;GO:0051930;GO:0060079;GO:0070256;GO:1900453","K04265-ko04071 Sphingolipid signaling pathway;ko04024 cAMP signaling pathway;ko04022 cGMP - PKG signaling pathway;ko04080 Neuroactive ligand-receptor interaction;ko04923 Regulation of lipolysis in adipocyte;ko04924 Renin secretion;ko05032 Morphine addiction","KOG4220-Muscarinic acetylcholine receptor[T]"]
["KRT5",408.272003,12.732251,-5.002971231,0,0,"down","KRT5","keratin 5","GO:0005198;GO:0005882;GO:0045095","-","KOG0977-Nuclear envelope protein lamin, intermediate filament superfamily[DY]"]
["SLC6A15",8.828577,0.274285,-5.00843329,{"v":6.67e-226,"d":"6.67E-226"},{"v":8.07e-225,"d":"8.07E-225"},"down","SLC6A15","-","GO:0003333;GO:0005298;GO:0005328;GO:0005887;GO:0006836;GO:0015293;GO:0015804;GO:0015820;GO:0015824;GO:0016020;GO:0016021;GO:0055085;GO:1903825","-","KOG3659-Sodium-neurotransmitter symporter[T]"]
["LOC112533303",88.729874,2.682515,-5.047761776,{"v":3.83e-165,"d":"3.83E-165"},{"v":3.65e-164,"d":"3.65E-164"},"down","LOC112533303","-","-","-","-"]
["STAC",14.165668,0.416773,-5.086993007,0,0,"down","STAC","-","GO:0006936;GO:0030315;GO:0031234;GO:0034605;GO:0035556;GO:0044325;GO:0046872;GO:1901385;GO:1901387;GO:1903078;GO:2001259","-","KOG1843-Uncharacterized conserved protein[S]"]
["DAB1",12.933689,0.378569,-5.094433738,0,0,"down","DAB1","DAB1, reelin adaptor protein","-","-","KOG3535-Adaptor protein Disabled[T]"]
["LOC771994",13.418832,0.389271,-5.107340421,{"v":1.23e-92,"d":"1.23E-92"},{"v":7.88e-92,"d":"7.88E-92"},"down","LOC771994","-","-","-","-"]
["CNN1",530.466736,15.198025,-5.125306526,0,0,"down","CNN1","calponin 1","GO:0003779;GO:0005515;GO:0005516;GO:0005856;GO:0031032;GO:1904706","-","KOG2046-Calponin[Z]"]
["GALC",91.68969,2.626135,-5.125746533,0,0,"down","GALC","-","GO:0003824;GO:0004336;GO:0006683","K01202-ko00600 Sphingolipid metabolism;ko04142 Lysosome","-"]
["LOC107053674",24.987331,0.692586,-5.173059774,0,0,"down","LOC107053674","-","-","-","-"]
["WNT6",9.566915,0.264335,-5.177614414,{"v":7.84e-81,"d":"7.84E-81"},{"v":4.6e-80,"d":"4.60E-80"},"down","WNT6","Wnt family member 6","GO:0005102;GO:0005576;GO:0007275;GO:0016055","K00445-ko04310 Wnt signaling pathway;ko04390 Hippo signaling pathway;ko04150 mTOR signaling pathway;ko04550 Signaling pathways regulating pluripotency of stem cells;ko04916 Melanogenesis;ko05200 Pathways in cancer;ko05205 Proteoglycans in cancer;ko05217 Basal cell carcinoma;ko05224 Breast cancer;ko05166 HTLV-I infection","KOG3913-Wnt family of developmental regulators[T]"]
["ASB9",59.679546,1.522578,-5.292648518,0,0,"down","ASB9","ankyrin repeat and SOCS box containing 9","GO:0005622;GO:0016567;GO:0035556;GO:0045732","-","KOG4177-Ankyrin[M]"]
["LOC107080643",1697.379639,43.267807,-5.293871466,0,0,"down","LOC107080643","C-factor-like","-","-","-"]
["LOC107051734",7.77906,0.195717,-5.312754855,{"v":1.1e-27,"d":"1.10E-27"},{"v":3.7e-27,"d":"3.70E-27"},"down","LOC107051734","-","-","-","-"]
["LOC101748439",12.451123,0.312414,-5.316672953,{"v":1.51e-82,"d":"1.51E-82"},{"v":8.96e-82,"d":"8.96E-82"},"down","LOC101748439","-","-","-","-"]
["VGLL1",53.904263,1.350944,-5.318359595,0,0,"down","VGLL1","-","GO:0003713;GO:0005634;GO:0006355;GO:0008022;GO:0045944","-","-"]
["MYL4",22.167217,0.543049,-5.351201467,{"v":2.01e-109,"d":"2.01E-109"},{"v":1.43e-108,"d":"1.43E-108"},"down","MYL4","myosin, light chain 4, alkali; atrial, embryonic","GO:0002026;GO:0003785;GO:0005509;GO:0031672;GO:0032781;GO:0051015;GO:0060048","K12750-ko04260 Cardiac muscle contraction;ko04261 Adrenergic signaling in cardiomyocytes","-"]
["OPCML",19.076998,0.463604,-5.362797339,0,0,"down","OPCML","opioid binding protein/cell adhesion molecule like","GO:0005886;GO:0007155;GO:0016020;GO:0031225","-","KOG3513-Neural cell adhesion molecule L1[T]"]
["TRPA1",5.202971,0.122509,-5.408376022,{"v":1.45e-95,"d":"1.45E-95"},{"v":9.48e-95,"d":"9.48E-95"},"down","TRPA1","transient receptor potential cation channel subfamily A member 1","GO:0005216;GO:0005262;GO:0005887;GO:0006811;GO:0006816;GO:0007166;GO:0009409;GO:0010033;GO:0014070;GO:0015267;GO:0015278;GO:0016020;GO:0016021;GO:0019233;GO:0032421;GO:0034220;GO:0042493;GO:0042542;GO:0042802;GO:0048265;GO:0050955;GO:0050966;GO:0050968;GO:0051209;GO:0051289;GO:0055085;GO:0070588;GO:0097604","-","KOG0510-Ankyrin repeat protein[R]"]
["SERPINB10B",141.064117,3.286345,-5.423723299,0,0,"down","SERPINB10B","serpin peptidase inhibitor, clade B (ovalbumin), member 10 B","-","-","KOG2392-Serpin[V]"]
["FHL2",134.047043,2.99778,-5.482701073,0,0,"down","FHL2","-","GO:0000122;GO:0001649;GO:0005634;GO:0006357;GO:0008134;GO:0009725;GO:0030018;GO:0042802;GO:0043066;GO:0045892;GO:0046872;GO:0055014;GO:0055015;GO:0060347;GO:0070885","-","KOG2272-Focal adhesion protein PINCH-1, contains LIM domains[TZ]"]
["TMEM136-1",37.945549,0.822408,-5.527932559,0,0,"down","TMEM136-1","transmembrane protein 136 family member 1","GO:0016020;GO:0016021","-","-"]
["SYTL5",9.441365,0.202804,-5.540837442,0,0,"down","SYTL5","-","-","-","KOG1028-Ca2+-dependent phospholipid-binding protein Synaptotagmin, required for synaptic vesicle and secretory granule exocytosis[TU]"]
["PRKG2",5.149365,0.108613,-5.567125839,{"v":2.18e-204,"d":"2.18E-204"},{"v":2.46e-203,"d":"2.46E-203"},"down","PRKG2","-","GO:0000166;GO:0004672;GO:0004674;GO:0004692;GO:0005524;GO:0006468;GO:0016301;GO:0016310;GO:0016740;GO:0030553","K19477-ko04022 cGMP - PKG signaling pathway;ko04540 Gap junction;ko04611 Platelet activation;ko04923 Regulation of lipolysis in adipocyte;ko04924 Renin secretion;ko04970 Salivary secretion;ko04730 Long-term depression;ko04740 Olfactory transduction;ko04713 Circadian entrainment","KOG0614-cGMP-dependent protein kinase[T]"]
["GJB2",220.885422,4.621418,-5.578818812,0,0,"down","GJB2","gap junction protein beta 2","GO:0005886;GO:0005921;GO:0005922;GO:0007154;GO:0016020;GO:0016021;GO:0030054","-","-"]
["CLDN7",139.765656,2.773212,-5.655308179,0,0,"down","CLDN7","-","-","-","-"]
["NPY7R",8.998533,0.176213,-5.674297556,{"v":8.34e-62,"d":"8.34E-62"},{"v":4.2e-61,"d":"4.20E-61"},"down","NPY7R","neuropeptide Y7 receptor","GO:0004930;GO:0004983;GO:0007165;GO:0007186;GO:0007218;GO:0016020;GO:0016021","K04205-ko04080 Neuroactive ligand-receptor interaction","KOG4219-G protein-coupled receptor[T]"]
["FOXE1",48.68964,0.948679,-5.681551012,0,0,"down","FOXE1","-","GO:0000981;GO:0001654;GO:0002088;GO:0002930;GO:0003677;GO:0003700;GO:0005634;GO:0005667;GO:0006355;GO:0006357;GO:0006366;GO:0009653;GO:0030154;GO:0042789;GO:0043010;GO:0043066;GO:0043565;GO:0048468;GO:0050679;GO:0061072;GO:0061073;GO:0061303;GO:0071157;GO:1902747;GO:2001111","-","-"]
["ALDOB",311.541138,5.95929,-5.708138413,0,0,"down","ALDOB","aldolase B, fructose-bisphosphate","GO:0001889;GO:0003824;GO:0004332;GO:0005737;GO:0005815;GO:0005829;GO:0005856;GO:0006000;GO:0006094;GO:0006096;GO:0006116;GO:0008092;GO:0016829;GO:0030388;GO:0032781;GO:0034451;GO:0042802;GO:0051117;GO:0061609;GO:0070061;GO:0070062;GO:0070072","K01623-ko01200 Carbon metabolism;ko01230 Biosynthesis of amino acids;ko00010 Glycolysis / Gluconeogenesis;ko00030 Pentose phosphate pathway;ko00051 Fructose and mannose metabolism;ko00710 Carbon fixation in photosynthetic organisms;ko00680 Methane metabolism","KOG1557-Fructose-biphosphate aldolase[G]"]
["DUOX2",38.092125,0.721528,-5.72229358,0,0,"down","DUOX2","-","GO:0004601;GO:0005509;GO:0006979;GO:0016020;GO:0016021;GO:0016174;GO:0016491;GO:0020037;GO:0050665;GO:0055114;GO:0098869","-","KOG0039-Ferric reductase, NADH/NADPH oxidase and related proteins[PQ]"]
["PCP4",1384.991333,26.062258,-5.731771055,0,0,"down","PCP4","Purkinje cell protein 4","GO:0005509;GO:0005516;GO:0032991;GO:0045666;GO:0099004","-","-"]
["NTSR1",16.594948,0.294361,-5.817013758,{"v":1.01e-127,"d":"1.01E-127"},{"v":7.97e-127,"d":"7.97E-127"},"down","NTSR1","neurotensin receptor 1","GO:0004930;GO:0005887;GO:0007165;GO:0007186;GO:0007218;GO:0008344;GO:0016020;GO:0016021;GO:0016492;GO:0042802;GO:0043066;GO:0045121","K04211-ko04020 Calcium signaling pathway;ko04080 Neuroactive ligand-receptor interaction","KOG4219-G protein-coupled receptor[T]"]
["TRIM29",92.088699,1.60408,-5.843206122,0,0,"down","TRIM29","-","GO:0000122;GO:0002039;GO:0005622;GO:0005737;GO:0008270;GO:0042802;GO:1900181","-","-"]
["LOC107052328",5.388788,0.093503,-5.848804367,{"v":3.91e-71,"d":"3.91E-71"},{"v":2.13e-70,"d":"2.13E-70"},"down","LOC107052328","-","-","-","-"]
["MYH11",2432.937744,41.213242,-5.883447637,0,0,"down","MYH11","myosin, heavy chain 11, smooth muscle","GO:0000146;GO:0000166;GO:0000287;GO:0003774;GO:0003779;GO:0005515;GO:0005516;GO:0005524;GO:0005737;GO:0005859;GO:0006939;GO:0008307;GO:0016459;GO:0030016;GO:0030239;GO:0030241;GO:0030898;GO:0032027;GO:0032982;GO:0043531;GO:0045159;GO:0046982;GO:0048251;GO:0048739;GO:0051015","K10352-ko04530 Tight junction","KOG0161-Myosin class II heavy chain[Z]"]
["LIPML2",9.640726,0.160832,-5.905515407,{"v":8.81e-216,"d":"8.81E-216"},{"v":1.03e-214,"d":"1.03E-214"},"down","LIPML2","-","GO:0006629;GO:0016042;GO:0016787;GO:0016788","-","-"]
["PADIL",85.651772,1.418862,-5.91567691,0,0,"down","PADIL","peptidyl arginine deiminase-like","GO:0004668;GO:0005509;GO:0005623;GO:0005634;GO:0005737;GO:0018101;GO:0036414","-","-"]
["C6orf58",7.764732,0.120879,-6.005300595,{"v":4.01e-59,"d":"4.01E-59"},{"v":1.98e-58,"d":"1.98E-58"},"down","C6orf58","-","GO:0005615","-","-"]
["PLIN3",13.05891,0.192701,-6.082526615,{"v":8.51e-225,"d":"8.51E-225"},{"v":1.03e-223,"d":"1.03E-223"},"down","PLIN3","-","-","-","-"]
["OTOGL",15.002823,0.216044,-6.117765015,0,0,"down","OTOGL","-","GO:0005576;GO:0007605;GO:0046373;GO:0046556","-","-"]
["EMP1",2902.295166,41.140228,-6.140500651,0,0,"down","EMP1","epithelial membrane protein 1","GO:0005886;GO:0008219;GO:0016020;GO:0016021;GO:0032060","-","-"]
["SFN",1225.010498,17.190125,-6.155070267,0,0,"down","SFN","stratifin","GO:0000079;GO:0001836;GO:0003334;GO:0005634;GO:0005737;GO:0005829;GO:0008630;GO:0010482;GO:0010839;GO:0019901;GO:0019904;GO:0030216;GO:0030307;GO:0031424;GO:0042802;GO:0043154;GO:0043588;GO:0045606;GO:0046827;GO:0051219;GO:0051726;GO:0061436","K06644-ko04110 Cell cycle;ko04115 p53 signaling pathway;ko04960 Aldosterone-regulated sodium reabsorption","KOG0841-Multifunctional chaperone (14-3-3 family)[O]"]
["ARID3C",34.750072,0.469692,-6.209157136,0,0,"down","ARID3C","-","GO:0000977;GO:0001228;GO:0003677;GO:0005634;GO:0006366;GO:0045944","-","KOG2744-DNA-binding proteins Bright/BRCAA1/RBP1 and related proteins containing BRIGHT domain[K]"]
["SPINT4",239.391449,3.165051,-6.240999064,0,0,"down","SPINT4","-","-","-","-"]
["P2RY4",11.649109,0.149601,-6.282955983,{"v":5.34e-122,"d":"5.34E-122"},{"v":4.11e-121,"d":"4.11E-121"},"down","P2RY4","-","GO:0004930;GO:0007165;GO:0007186;GO:0016020;GO:0016021;GO:0030321;GO:0035589;GO:0045028;GO:0045030;GO:0071380","K04271-ko04080 Neuroactive ligand-receptor interaction;ko04742 Taste transduction","KOG4219-G protein-coupled receptor[T]"]
["SH3RF2",11.03568,0.140162,-6.298936452,{"v":2.58e-252,"d":"2.58E-252"},{"v":3.42e-251,"d":"3.42E-251"},"down","SH3RF2","-","GO:0005634;GO:0005654;GO:0008157;GO:0010923;GO:0019902;GO:0030335;GO:0031397;GO:0032436;GO:0043066;GO:0046330;GO:0051865;GO:0061630","-","KOG4225-Sorbin and SH3 domain-containing protein[T]"]
["CRYBB2",38.707504,0.42876,-6.49629915,{"v":4.75e-182,"d":"4.75E-182"},{"v":4.86e-181,"d":"4.86E-181"},"down","CRYBB2","crystallin beta B2","GO:0005212;GO:0007601","-","-"]
["S100A14",273.142578,2.855917,-6.57955636,0,0,"down","S100A14","-","GO:0005509;GO:0005829;GO:0005886;GO:0016604;GO:0030054;GO:0032496;GO:0034142;GO:0042379;GO:0042742;GO:0048471;GO:0071624;GO:0090026","-","-"]
["FOXF2",12.850517,0.132554,-6.599102386,{"v":3.16e-206,"d":"3.16E-206"},{"v":3.59e-205,"d":"3.59E-205"},"down","FOXF2","-","-","-","KOG3562-Forkhead/HNF-3-related transcription factor[K]"]
["LOC112532406",5.730371,0.05868,-6.609615865,{"v":6.63e-88,"d":"6.63E-88"},{"v":4.1e-87,"d":"4.10E-87"},"down","LOC112532406","-","-","-","-"]
["BEST1",13.223954,0.127498,-6.696535185,{"v":5.24e-280,"d":"5.24E-280"},{"v":7.51e-279,"d":"7.51E-279"},"down","BEST1","-","GO:0005254;GO:0005886;GO:0006811;GO:0006821;GO:0007601;GO:0016020;GO:0016021;GO:0034707;GO:0046872;GO:0050908;GO:0051924;GO:1902476","-","KOG3547-Bestrophin (Best vitelliform macular dystrophy-associated protein)[R]"]
["CXCL14",94.856262,0.855542,-6.792760526,0,0,"down","CXCL14","C-X-C motif chemokine ligand 14","-","K10033-ko04060 Cytokine-cytokine receptor interaction;ko04062 Chemokine signaling pathway","-"]
["LYPD2",28.608299,0.253599,-6.817740853,0,0,"down","LYPD2","-","-","-","-"]
["LOC107051838",5.540348,0.048697,-6.82999989,{"v":2.25e-49,"d":"2.25E-49"},{"v":1.01e-48,"d":"1.01E-48"},"down","LOC107051838","-","-","-","-"]
["COL6A6",24.109512,0.209621,-6.845675385,0,0,"down","COL6A6","-","-","K06238-ko04151 PI3K-Akt signaling pathway;ko04512 ECM-receptor interaction;ko04510 Focal adhesion;ko04974 Protein digestion and absorption","-"]
["PKP1",179.622131,1.542184,-6.863846398,0,0,"down","PKP1","-","GO:0005521;GO:0005634;GO:0005654;GO:0005886;GO:0007155;GO:0010628;GO:0030057;GO:0043231;GO:0045110;GO:0098609;GO:1902373;GO:1990124","-","KOG1048-Neural adherens junction protein Plakophilin and related Armadillo repeat proteins[TW]"]
["ACTG2",3916.746094,33.361862,-6.875311986,0,0,"down","ACTG2","actin, gamma 2, smooth muscle, enteric","GO:0000166;GO:0005524;GO:0005737;GO:0005856;GO:0071944","K12315-ko04270 Vascular smooth muscle contraction","KOG0676-Actin and related proteins[Z]"]
["DSG4",86.857071,0.716856,-6.920816149,0,0,"down","DSG4","-","GO:0005509;GO:0005886;GO:0005911;GO:0007155;GO:0007156;GO:0009898;GO:0016020;GO:0016021;GO:0045295;GO:0050821","-","-"]
["XG",256.281982,1.944362,-7.042291399,0,0,"down","XG","-","GO:0016020;GO:0016021","-","-"]
["CLIC5",27.228004,0.198989,-7.096258735,0,0,"down","CLIC5","-","GO:0004364;GO:0005244;GO:0005254;GO:0005634;GO:0005737;GO:0006749;GO:0006811;GO:0006821;GO:0007605;GO:0015629;GO:0016020;GO:0034220;GO:0034707;GO:0034765;GO:0060088;GO:1902476","-","KOG1422-Intracellular Cl- channel CLIC, contains GST domain[P]"]
["VSIG1",99.526436,0.714062,-7.122886627,0,0,"down","VSIG1","V-set and immunoglobulin domain containing 1","GO:0003382;GO:0005886;GO:0016020;GO:0016021;GO:0030277;GO:0003382;GO:0005886;GO:0016020;GO:0016021;GO:0030277","-","KOG4222-Axon guidance receptor Dscam[T]"]
["TMPRSS11F",82.401413,0.584947,-7.138219353,0,0,"down","TMPRSS11F","-","GO:0004252;GO:0005576;GO:0005887;GO:0006508;GO:0008233;GO:0008236;GO:0016020;GO:0016021;GO:0016787","-","-"]
["SERPINB1",297.708282,1.81382,-7.358724254,0,0,"down","SERPINB1","-","GO:0004867;GO:0005615;GO:0010951","-","KOG2392-Serpin[V]"]
["SPIK2",694.429626,4.136854,-7.391150646,0,0,"down","SPIK2","-","-","-","-"]
["LOC107049667",8264.71582,47.845924,-7.432425377,0,0,"down","LOC107049667","-","-","-","-"]
["C9H2orf54",37.708942,0.197787,-7.574815258,0,0,"down","C9H2orf54","-","-","-","-"]
["PITHD1",45.487141,0.216717,-7.713502622,{"v":1.18e-190,"d":"1.18E-190"},{"v":1.25e-189,"d":"1.25E-189"},"down","PITHD1","-","GO:0005634;GO:0006974","-","KOG1730-Thioredoxin-like protein[O]"]
["SOT3A1L",62.927883,0.295674,-7.733548213,0,0,"down","SOT3A1L","sulfotransferase family 3A, member 1-like","GO:0008146;GO:0016740","-","KOG1584-Sulfotransferase[R]"]
["SLC34A2",31.135803,0.127951,-7.926839254,0,0,"down","SLC34A2","solute carrier family 34 member 2","GO:0005436;GO:0005886;GO:0005903;GO:0006817;GO:0015321;GO:0016020;GO:0016021;GO:0016324;GO:0030643;GO:0031402;GO:0035725;GO:0042301;GO:0043627;GO:0044341","-","-"]
["TESPA1",77.003052,0.300759,-8.000163908,0,0,"down","TESPA1","-","GO:0005102;GO:0010387;GO:0050862","-","-"]
["DUOXA1L",54.78558,0.208014,-8.040971775,0,0,"down","DUOXA1L","-","GO:0005789;GO:0015031;GO:0016020;GO:0016021","-","-"]
["POFUT2",21.819822,0.078518,-8.118400192,0,0,"down","POFUT2","-","GO:0001707;GO:0005794;GO:0005975;GO:0006004;GO:0008417;GO:0010468;GO:0010717;GO:0016740;GO:0016757;GO:0036065;GO:0036066;GO:0046922;GO:0051046","K03691-ko00514 Other types of O-glycan biosynthesis","-"]
["MIR34A",6.358132,0.022861,-8.119570646,{"v":3.85e-05,"d":"3.85E-05"},{"v":6.62e-05,"d":"6.62E-05"},"down","MIR34A","microRNA 34a","-","-","-"]
["RHCG",44.327679,0.139941,-8.307245309,0,0,"down","RHCG","Rh family C glycoprotein","GO:0005886;GO:0005887;GO:0006873;GO:0006885;GO:0008519;GO:0015695;GO:0015696;GO:0016020;GO:0016021;GO:0016323;GO:0016324;GO:0030506;GO:0042802;GO:0070634;GO:0072488","-","KOG3796-Ammonium transporter RHBG[UR]"]
["GAL3ST2",15.786309,0.049396,-8.320063959,{"v":3.2e-129,"d":"3.20E-129"},{"v":2.55e-128,"d":"2.55E-128"},"down","GAL3ST2","galactose-3-O-sulfotransferase 2","GO:0001733;GO:0005794;GO:0008146;GO:0009247;GO:0016021","-","-"]
["LOC112532718",55.54039,0.173117,-8.325646094,0,0,"down","LOC112532718","-","-","-","-"]
["REG4",46.55624,0.114737,-8.664500035,{"v":5.16e-134,"d":"5.16E-134"},{"v":4.25e-133,"d":"4.25E-133"},"down","REG4","regenerating family member 4","GO:0005737;GO:0008201;GO:0009617;GO:2001065","-","-"]
["IL4I1",286.010498,0.566979,-8.978557086,0,0,"down","IL4I1","interleukin 4 induced 1","GO:0016491;GO:0055114","K03334-ko00250 Alanine, aspartate and glutamate metabolism;ko00270 Cysteine and methionine metabolism;ko00280 Valine, leucine and isoleucine degradation;ko00350 Tyrosine metabolism;ko00360 Phenylalanine metabolism;ko00380 Tryptophan metabolism;ko00400 Phenylalanine, tyrosine and tryptophan biosynthesis;ko00950 Isoquinoline alkaloid biosynthesis","KOG0029-Amine oxidase[Q]"]
["LOC101747386",1510.856079,1.985149,-9.571903227,0,0,"down","LOC101747386","-","-","-","-"]
["PLAC8L1",863.131348,1.087293,-9.632695544,0,0,"down","PLAC8L1","Placenta-specific 8-like 1","-","-","-"]
["KRT15",19787.20117,18.780064,-10.04114987,0,0,"down","KRT15","keratin 15","GO:0005198;GO:0005882","-","KOG0977-Nuclear envelope protein lamin, intermediate filament superfamily[DY]"]
["MAL",1749.946533,1.107152,-10.62624183,0,0,"down","MAL","mal, T-cell differentiation protein","GO:0001766;GO:0005783;GO:0008104;GO:0016020;GO:0016021;GO:0019911;GO:0042552;GO:0045121","-","-"]
["LOC112533546",32.655468,0.020273,-10.65354927,{"v":1.3e-198,"d":"1.30E-198"},{"v":1.42e-197,"d":"1.42E-197"},"down","LOC112533546","-","-","-","-"]
["TSPAN8",136.134186,0.075626,-10.81385947,0,0,"down","TSPAN8","tetraspanin 8","GO:0005887;GO:0007166;GO:0007283;GO:0009986;GO:0010468;GO:0016020;GO:0016021","-","KOG3882-Tetraspanin family integral membrane protein[R]"]
["TACR2",30.196028,0.016309,-10.85447475,0,0,"down","TACR2","-","GO:0004930;GO:0004995;GO:0005886;GO:0007165;GO:0007186;GO:0007217;GO:0007268;GO:0016020;GO:0016021;GO:0016497;GO:0036126;GO:0045987;GO:0061827;GO:0070472;GO:0097225;GO:1902093","K04223-ko04020 Calcium signaling pathway;ko04080 Neuroactive ligand-receptor interaction","KOG4219-G protein-coupled receptor[T]"]
["LOC112532717",889.746033,0.373227,-11.21912452,0,0,"down","LOC112532717","-","-","-","-"]
["LOC107049019",475.550049,0.097117,-12.25758571,0,0,"down","LOC107049019","-","-","-","-"]
["CSTA",10573.19727,2.023324,-12.35139672,0,0,"down","CSTA","-","GO:0001533;GO:0002020;GO:0004866;GO:0004869;GO:0005198;GO:0005615;GO:0005622;GO:0005634;GO:0005737;GO:0005829;GO:0010466;GO:0010951;GO:0018149;GO:0030216;GO:0030674;GO:0045861;GO:0098609","-","-"]
["CRISP2",3038.125732,0.432773,-12.77728346,0,0,"down","CRISP2","-","GO:0005576","-","KOG3017-Defense-related protein containing SCP domain[S]"]
["LOC770450",5194.581543,0.713918,-12.82896154,0,0,"down","LOC770450","-","GO:0004867;GO:0010951","-","-"]
["LOC112529929",15658.71094,0.879187,-14.12043587,0,0,"down","LOC112529929","-","-","-","-"]
["CACNG3",5.171707,0.0001,-15.65835292,{"v":6.99e-44,"d":"6.99E-44"},{"v":2.96e-43,"d":"2.96E-43"},"down","CACNG3","calcium voltage-gated channel auxiliary subunit gamma 3","GO:0005244;GO:0005262;GO:0005622;GO:0006605;GO:0006811;GO:0006816;GO:0008104;GO:0016020;GO:0016021;GO:0032281;GO:0034765;GO:0036477;GO:0070588;GO:0098685;GO:0098978;GO:0099061;GO:0099645","K04868-ko04010 MAPK signaling pathway;ko04921 Oxytocin signaling pathway;ko04260 Cardiac muscle contraction;ko04261 Adrenergic signaling in cardiomyocytes;ko05410 Hypertrophic cardiomyopathy (HCM);ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC);ko05414 Dilated cardiomyopathy (DCM)","-"]
["FAM83A",5.364316,0.0001,-15.71110661,{"v":6.31e-77,"d":"6.31E-77"},{"v":3.58e-76,"d":"3.58E-76"},"down","FAM83A","-","GO:0007173;GO:0008283;GO:0019901;GO:0036312","-","-"]
["LOC101749284",5.421635,0.0001,-15.72644037,{"v":4.62e-34,"d":"4.62E-34"},{"v":1.71e-33,"d":"1.71E-33"},"down","LOC101749284","-","-","-","-"]
["LOC101749502",5.795733,0.0001,-15.82270351,{"v":4.13e-32,"d":"4.13E-32"},{"v":1.49e-31,"d":"1.49E-31"},"down","LOC101749502","-","GO:0004867;GO:0010951","-","-"]
["CLC2IL1",6.219676,0.0001,-15.92455181,{"v":4.46e-41,"d":"4.46E-41"},{"v":1.83e-40,"d":"1.83E-40"},"down","CLC2IL1","-","-","-","-"]
["AGXT",6.332425,0.0001,-15.95047046,{"v":3.5e-45,"d":"3.50E-45"},{"v":1.5e-44,"d":"1.50E-44"},"down","AGXT","-","GO:0003824;GO:0004760;GO:0005102;GO:0005777;GO:0005782;GO:0007219;GO:0008453;GO:0008483;GO:0009436;GO:0016597;GO:0019265;GO:0019448;GO:0030170;GO:0042802;GO:0042803;GO:0042853;GO:0043231;GO:0043621;GO:0046487;GO:0046724","K00830-ko01200 Carbon metabolism;ko00630 Glyoxylate and dicarboxylate metabolism;ko00680 Methane metabolism;ko00250 Alanine, aspartate and glutamate metabolism;ko00260 Glycine, serine and threonine metabolism;ko04146 Peroxisome","KOG2862-Alanine-glyoxylate aminotransferase AGT1[R]"]
["DMRT3",7.097319,0.0001,-16.11498653,{"v":1.58e-62,"d":"1.58E-62"},{"v":7.99e-62,"d":"7.99E-62"},"down","DMRT3","-","GO:0003677;GO:0003700;GO:0005634;GO:0006355;GO:0007628;GO:0019226;GO:0021521;GO:0042487;GO:0043565;GO:0046661;GO:0046872;GO:0046982","-","KOG3815-Transcription factor Doublesex[K]"]
["LOC101748035",7.25853,0.0001,-16.14738978,{"v":1.19e-49,"d":"1.19E-49"},{"v":5.34e-49,"d":"5.34E-49"},"down","LOC101748035","-","-","-","-"]
["FCGBP",7.473272,0.0001,-16.18945241,0,0,"down","FCGBP","-","-","-","-"]
["CLCA2",7.634174,0.0001,-16.22018445,{"v":7.65e-134,"d":"7.65E-134"},{"v":6.28e-133,"d":"6.28E-133"},"down","CLCA2","-","-","-","-"]
["LOC107055203",7.69054,0.0001,-16.23079728,{"v":2.2e-38,"d":"2.20E-38"},{"v":8.65e-38,"d":"8.65E-38"},"down","LOC107055203","-","-","-","-"]
["CFC1",7.692782,0.0001,-16.23121781,{"v":9.62e-41,"d":"9.62E-41"},{"v":3.92e-40,"d":"3.92E-40"},"down","CFC1","cripto, FRL-1, cryptic family 1","GO:0005576;GO:0005886;GO:0007275;GO:0007369;GO:0016020;GO:0031225","-","KOG1219-Uncharacterized conserved protein, contains laminin, cadherin and EGF domains[T]"]
["ADCY8",7.878141,0.0001,-16.26556762,{"v":3.01e-107,"d":"3.01E-107"},{"v":2.11e-106,"d":"2.11E-106"},"down","ADCY8","-","GO:0000166;GO:0004016;GO:0005524;GO:0005622;GO:0005886;GO:0006171;GO:0007616;GO:0009190;GO:0016020;GO:0016021;GO:0016829;GO:0016849;GO:0035556;GO:0046872;GO:0050804;GO:0098685;GO:0098686;GO:0098978;GO:0099056","K08048-ko00230 Purine metabolism;ko04015 Rap1 signaling pathway;ko04020 Calcium signaling pathway;ko04072 Phospholipase D signaling pathway;ko04024 cAMP signaling pathway;ko04022 cGMP - PKG signaling pathway;ko04114 Oocyte meiosis;ko04540 Gap junction;ko04611 Platelet activation;ko04062 Chemokine signaling pathway;ko04911 Insulin secretion;ko04923 Regulation of lipolysis in adipocyte;ko04912 GnRH signaling pathway;ko04913 Ovarian Steroidogenesis;ko04915 Estrogen signaling pathway;ko04914 Progesterone-mediated oocyte maturation;ko04921 Oxytocin signaling pathway;ko04918 Thyroid hormone synthesis;ko04916 Melanogenesis;ko04925 Aldosterone synthesis and secretion;ko04261 Adrenergic signaling in cardiomyocytes;ko04270 Vascular smooth muscle contraction;ko04970 Salivary secretion;ko04971 Gastric acid secretion;ko04972 Pancreatic secretion;ko04976 Bile secretion;ko04724 Glutamatergic synapse;ko04727 GABAergic synapse;ko04725 Cholinergic synapse;ko04720 Long-term potentiation;ko04723 Retrograde endocannabinoid signaling;ko04742 Taste transduction;ko04750 Inflammatory mediator regulation of TRP channels;ko04211 Longevity regulating pathway - mammal;ko04213 Longevity regulating pathway - multiple species;ko04713 Circadian entrainment;ko05200 Pathways in cancer;ko05032 Morphine addiction;ko05414 Dilated cardiomyopathy (DCM);ko05166 HTLV-I infection;ko01522 Endocrine resistance","KOG3619-Adenylate/guanylate cyclase[C]"]
["LOC101751113",8.728997,0.0001,-16.41352827,{"v":1.76e-99,"d":"1.76E-99"},{"v":1.17e-98,"d":"1.17E-98"},"down","LOC101751113","-","-","-","-"]
["GALR1",9.889988,0.0001,-16.59368115,{"v":3.53e-49,"d":"3.53E-49"},{"v":1.58e-48,"d":"1.58E-48"},"down","GALR1","galanin receptor 1","GO:0004930;GO:0004966;GO:0005623;GO:0007165;GO:0007186;GO:0007194;GO:0007204;GO:0007218;GO:0016020;GO:0016021","K04230-ko04080 Neuroactive ligand-receptor interaction","KOG4219-G protein-coupled receptor[T]"]
["NMU",10.155159,0.0001,-16.6318533,{"v":4.61e-43,"d":"4.61E-43"},{"v":1.93e-42,"d":"1.93E-42"},"down","NMU","neuromedin U","GO:0001659;GO:0005179;GO:0005576;GO:0006940;GO:0007218;GO:0010469;GO:0031839;GO:0031840;GO:0060259;GO:0097009;GO:2000821","K05249-ko04080 Neuroactive ligand-receptor interaction","-"]
["GPR87",10.506906,0.0001,-16.68097837,{"v":4.49e-135,"d":"4.49E-135"},{"v":3.72e-134,"d":"3.72E-134"},"down","GPR87","-","GO:0004930;GO:0005887;GO:0007165;GO:0007186;GO:0016020;GO:0016021;GO:0035589;GO:0045028","-","KOG4219-G protein-coupled receptor[T]"]
["NPPC",11.174618,0.0001,-16.76986599,0.001287692,0.001973407,"down","NPPC","-","GO:0003418;GO:0003419;GO:0005179;GO:0005576;GO:0006182;GO:0007168;GO:0010469;GO:0050880","K12336-ko04270 Vascular smooth muscle contraction","-"]
["LOC107051767",11.772682,0.0001,-16.8450835,{"v":2.6e-94,"d":"2.60E-94"},{"v":1.68e-93,"d":"1.68E-93"},"down","LOC107051767","-","-","-","-"]
["LOC107055433",13.949308,0.0001,-17.08983403,{"v":2.27e-44,"d":"2.27E-44"},{"v":9.64e-44,"d":"9.64E-44"},"down","LOC107055433","-","-","-","-"]
["EDCH5",17.195749,0.0001,-17.39169243,{"v":2.7e-66,"d":"2.70E-66"},{"v":1.41e-65,"d":"1.41E-65"},"down","EDCH5","epidermal differentiation protein containing cysteine histidine motifs 5","-","-","-"]
["BTN3A2",18.427288,0.0001,-17.49148424,{"v":6.26e-121,"d":"6.26E-121"},{"v":4.78e-120,"d":"4.78E-120"},"down","BTN3A2","-","-","-","-"]
["CDKN2B",18.521559,0.0001,-17.49884601,{"v":1.64e-121,"d":"1.64E-121"},{"v":1.26e-120,"d":"1.26E-120"},"down","CDKN2B","cyclin dependent kinase inhibitor 2B","GO:0048536;GO:2000134","K04685-ko04350 TGF-beta signaling pathway;ko04068 FoxO signaling pathway;ko04110 Cell cycle;ko05200 Pathways in cancer;ko05203 Viral carcinogenesis;ko05222 Small cell lung cancer;ko05166 HTLV-I infection","KOG0508-Ankyrin repeat protein[R]"]
["LOC107055090",18.764143,0.0001,-17.51761888,{"v":5.13e-78,"d":"5.13E-78"},{"v":2.94e-77,"d":"2.94E-77"},"down","LOC107055090","-","-","-","-"]
["LOC107053668",22.71703,0.0001,-17.79341471,{"v":5.72e-76,"d":"5.72E-76"},{"v":3.23e-75,"d":"3.23E-75"},"down","LOC107053668","-","-","-","-"]
["LRMPL",24.599346,0.0001,-17.90826043,{"v":3.3e-122,"d":"3.30E-122"},{"v":2.54e-121,"d":"2.54E-121"},"down","LRMPL","-","-","-","-"]
["LOC408038",30.061277,0.0001,-18.19754677,{"v":1.13e-93,"d":"1.13E-93"},{"v":7.26e-93,"d":"7.26E-93"},"down","LOC408038","beta-keratin","GO:0005200;GO:0005882;GO:0007010","-","-"]
["LOC428667",30.564043,0.0001,-18.22147587,{"v":2.31e-148,"d":"2.31E-148"},{"v":2.03e-147,"d":"2.03E-147"},"down","LOC428667","-","-","-","-"]
["CYP2C23b",32.823559,0.0001,-18.32437215,{"v":1.18e-204,"d":"1.18E-204"},{"v":1.33e-203,"d":"1.33E-203"},"down","CYP2C23b","cytochrome P450, family 2, subfamily C, polypeptide 23b","GO:0004497;GO:0005506;GO:0005623;GO:0008392;GO:0008395;GO:0016491;GO:0016705;GO:0019373;GO:0020037;GO:0042493;GO:0046872;GO:0055114","-","KOG0156-Cytochrome P450 CYP2 subfamily[Q]"]
["LOC107049000",40.415382,0.0001,-18.62454496,{"v":3.4e-174,"d":"3.40E-174"},{"v":3.36e-173,"d":"3.36E-173"},"down","LOC107049000","-","GO:0016020;GO:0016021","-","-"]
["LOC426827",42.299934,0.0001,-18.69029589,{"v":5.64e-173,"d":"5.64E-173"},{"v":5.55e-172,"d":"5.55E-172"},"down","LOC426827","-","-","-","-"]
["CLCA1",43.667667,0.0001,-18.73620593,0,0,"down","CLCA1","-","GO:0005229;GO:0005887;GO:0006821;GO:0016020;GO:0016021;GO:1902476","-","-"]
["PROM2",48.004642,0.0001,-18.87281439,0,0,"down","PROM2","-","GO:0001934;GO:0005886;GO:0009986;GO:0016020;GO:0016021;GO:0031346;GO:0042995;GO:0043087;GO:0048550;GO:0071914;GO:2001287","-","KOG4331-Polytopic membrane protein Prominin[R]"]
["LOC107055478",53.934204,0.0001,-19.04084097,{"v":7.15e-216,"d":"7.15E-216"},{"v":8.38e-215,"d":"8.38E-215"},"down","LOC107055478","-","-","-","-"]
["BTN3A3",70.349274,0.0001,-19.42417601,0,0,"down","BTN3A3","-","-","-","-"]
["EDMPN1",108.695717,0.0001,-20.05186366,{"v":9.52e-198,"d":"9.52E-198"},{"v":1.03e-196,"d":"1.03E-196"},"down","EDMPN1","epidermal differentiation protein containing a MPN sequence motif 1","-","-","-"]
["LOC101751942",115.381134,0.0001,-20.13797592,{"v":1.79e-168,"d":"1.79E-168"},{"v":1.73e-167,"d":"1.73E-167"},"down","LOC101751942","-","-","-","-"]
["DMBT1L3",120.668007,0.0001,-20.20261179,0,0,"down","DMBT1L3","-","GO:0005044;GO:0006898;GO:0016020","-","-"]
["CTSE",122.067299,0.0001,-20.21924533,0,0,"down","CTSE","-","GO:0004190;GO:0005768;GO:0006508;GO:0008233;GO:0016540;GO:0016787;GO:0019886;GO:0030163;GO:0042803","K01382-ko04142 Lysosome","KOG1339-Aspartyl protease[O]"]
["MSLNL",124.916237,0.0001,-20.25252958,0,0,"down","MSLNL","-","-","-","-"]
["DMBT1L",212.591797,0.0001,-21.0196545,0,0,"down","DMBT1L","deleted in malignant brain tumors 1 protein-like","-","-","-"]
["EDPE",289.558868,0.0001,-21.46542525,0,0,"down","EDPE","epidermal differentiation protein rich in proline and glutamic acid (E)","-","-","-"]
["CYP2C23a",326.14917,0.0001,-21.63710053,0,0,"down","CYP2C23a","cytochrome P450, family 2, subfamily C, polypeptide 23a","-","-","KOG0156-Cytochrome P450 CYP2 subfamily[Q]"]
["ADIRF",638.985291,0.0001,-22.60735129,0,0,"down","ADIRF","adipogenesis regulatory factor","GO:0005634;GO:0005654;GO:0005829;GO:0045600;GO:0045944;GO:0071478;GO:0072719;GO:2001023","-","-"]
["CRNN",17114.16406,0.0001,-27.35061559,0,0,"down","CRNN","cornulin","GO:0005509;GO:0046872;GO:0046914","-","-"]
[{"$nulls":10},-1]