# Shigellosis - Reference pathway

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- nt06121 TLR signaling (viruses and bacteria)
  - N01283 Shigella OspF to TLR2/4-MAPK signaling pathway
- nt06139 NLR signaling (viruses and bacteria)
  - N00941 Shigella IpaH9.8 to NOD-NFKB signaling pathway
  - N00948 Shigella IpaH7.8 to NLRP3 Inflammasome signaling pathway
  - N00949 Shigella IpaB to NLRC4 Inflammasome signaling pathway
- nt06134 CGAS-STING signaling (viruses and bacteria)
  - N00946 Shigella IpaJ to cGAS-STING signaling pathway
  - N00947 Shigella Ipa4.5 to cGAS-STING signaling pathway
- nt06123 TNF signaling (viruses and bacteria)
  - N00944 Shigella OspI to TNF-NFKB signaling pathway
  - N00945 Shigella IpaH1.4/2.5 to TNF-NFKB signaling pathway
  - N00927 Escherichia/Shigella NleE/OspZ to TNF-NFKB signaling pathway
  - N00942 Shigella OspG to TNF-NFKB signaling pathway
  - N00943 Shigella IpaH4.5 to TNF-NFKB signaling pathway
- nt06128 Autophagy (viruses and bacteria)
  - N01284 Shigella IcsP to Autophagy-vesicle elongation
- nt06131 Apoptosis (viruses and bacteria)
  - N00950 Shigella FimA to crosstalk between extrinsic and intrinsic apoptotic pathways
- nt06135 Cytoskeletal regulation (viruses and bacteria)
  - N01074 Shigella IpaA to ITGA/B-RhoGEF-RhoA signaling pathway
  - N01073 Shigella IpgB2 to ITGA/B-RhoGEF-RhoA signaling pathway
  - N01075 Shigella IcsB to ITGA/B-RhoGEF-RhoA signaling pathway
  - N01069 Shigella IpgB1 to ITGA/B-FAK-RAC signaling pathway
  - N01077 Shigella IcsB to ITGA/B-FAK-RAC signaling pathway
  - N00952 Shigella IpgB1 to ITGA/B-RHOG-RAC signaling pathway
  - N01071 Shigella IpgB1 to ITGA/B-FAK-CDC42 signaling pathway
  - N01076 Shigella IcsB to ITGA/B-FAK-CDC42 signaling pathway
  - N01067 Shigella IpgD to ARNO-ARF-ACTB_G signaling pathway
  - N01079 Shigella IpaC to Actin signaling pathway
  - N01081 Shigella IpaB/C/D to ITGA/B-TALIN/VINCULIN signaling pathway
  - N01083 Shigella OspE to ITGA/B-TALIN/VINCULIN signaling pathway
  - N01082 Shigella IpaA to ITGA/B-TALIN/VINCULIN signaling pathway