# Breast cancer - Reference pathway

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- nt06210 ERK signaling
  - N00041 EGFR-overexpression to RAS-ERK signaling pathway
  - N00022 ERBB2-overexpression to RAS-ERK signaling pathway
  - N00020 Amplified FGFR to RAS-ERK signaling pathway
- nt06214 PI3K signaling
  - N00042 EGFR-overexpression to PI3K signaling pathway
  - N00034 ERBB2-overexpression to PI3K signaling pathway
  - N00038 Amplified FGFR to PI3K signaling pathway
  - N00049 Mutation-activated PI3K to PI3K signaling pathway
  - N00050 Amplified PI3K to PI3K signaling pathway
  - N00052 Mutation-inactivated PTEN to PI3K signaling pathway
- nt06215 WNT signaling
  - N00059 FZD7-overexpression to Wnt signaling pathway
  - N00060 LRP6-overexpression to Wnt signaling pathway
- nt06216 NOTCH signaling
  - N00087 NOTCH-overexpression to Notch signaling pathway
- nt06227 Nuclear receptor signaling
  - N00287 ESR1-positive to nuclear-initiated estrogen signaling pathway
- nt06230 Cell cycle
  - N00275 Amplified CCND1 to cell cycle G1/S
- nt06240 Transcription
  - N00115 Mutation-inactivated TP53 to transcription