# Human immunodeficiency virus 1 infection - Reference pathway

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- nt06121 TLR signaling (viruses and bacteria)
  - N00436 HIV Tat to TLR2/4-NFKB signaling pathway
  - N00437 HIV Vpu to TLR2/4-NFKB signaling pathway
  - N00439 HIV Nef to TLR2/4-MAPK signaling pathway
- nt06134 CGAS-STING signaling (viruses and bacteria)
  - N00440 HIV Vpu/Vif/Vpr to cGAS-STING signaling pathway
- nt06123 TNF signaling (viruses and bacteria)
  - N00447 HIV Vpr/Tat to TNF-JNK signaling pathway
  - N00445 HIV Tat/Nef to TNF-p38 signaling pathway
  - N00441 HIV gp120 to TNF-NFKB signaling pathway
  - N00442 HIV Nef to TNF-NFKB signaling pathway
  - N00443 HIV Vpr/Nef/Tat to TNF-NFKB signaling pathway
- nt06124 Chemokine signaling (viruses)
  - N00432 HIV gp120 to CXCR4-GNAQ-PLCB/G-calcineurin
  - N00431 HIV gp120 to CXCR4-GNAI-PI3K-BAD signaling pathway
  - N00434 HIV gp120 to CXCR4-GNB/G-RAC signaling pathway
- nt06129 MHC presentation (viruses)
  - N00461 HIV Nef to antigen processing and presentation by MHC class I molecules
- nt06130 Cell cycle (viruses)
  - N00456 HIV Vpr to CDC25-cell cycle G2M
  - N00458 HIV Vpr to CDC25-cell cycle G2M
  - N00457 HIV Vpr to cell cycle G2M
  - N00460 HIV Vpr to WEE1-cell cycle G2M
- nt06131 Apoptosis (viruses and bacteria)
  - N00448 HIV Tat/Nef to crosstalk between extrinsic and intrinsic apoptotic pathways
  - N00449 HIV Tat/Nef to crosstalk between extrinsic and intrinsic apoptotic pathways
  - N00452 HIV Nef to intrinsic apoptotic pathway
  - N00453 HIV Vpr to intrinsic apoptotic pathway
  - N00451 HIV Tat to intrinsic apoptotic pathway
  - N00450 HIV Tat to intrinsic apoptotic pathway
  - N00454 HIV Vpr to intrinsic apoptotic pathway