# Hepatitis C - Reference pathway

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- nt06110 MAPK signaling (viruses and bacteria)
  - N00274 HCV NS5A to RAS-ERK signaling pathway
  - N00518 HCV Core to ERK signaling pathway
  - N00519 HCV Core to ERK signaling pathway
- nt06114 PI3K signaling (viruses)
  - N00272 HCV NS5A to PI3K signaling pathway
- nt06121 TLR signaling (viruses and bacteria)
  - N00516 HCV NS3/4A to TLR3-IRF3 signaling pathway
  - N00517 HCV NS3/4A to TLR3-IRF3 signaling pathway
- nt06133 RLR signaling (viruses)
  - N00271 HCV NS3/4A to RIG-I-like receptor signaling pathway
- nt06137 OAS/RNase L pathway (viruses)
  - N00273 HCV NS5A to oligoadenylate synthetase (OAS)/RNase L pathway
- nt06122 IFN signaling (viruses)
  - N00270 HCV Core to IFN signaling pathway
- nt06123 TNF signaling (viruses and bacteria)
  - N00525 HCV NS5A to TNF-NFKB signaling pathway
  - N00269 HCV core to TNF-NFKB signaling pathway
- nt06130 Cell cycle (viruses)
  - N00521 HCV Core to p21-cell cycle G1/S
  - N00520 HCV NS5A to p21-cell cycle G1/S
  - N00522 HCV NS3 to p21-cell cycle G1/S
  - N00523 HCV Core to p21-cell cycle G1/S
- nt06131 Apoptosis (viruses and bacteria)
  - N00524 HCV NS5A to extrinsic apoptotic pathway
  - N00528 HCV core to extrinsic apoptotic pathway
  - N00527 HCV Core to crosstalk between extrinsic and intrinsic apoptotic pathways
  - N00526 HCV NS3 to crosstalk between extrinsic and intrinsic apoptotic pathways
- nt06140 Transcription (viruses)
  - N00529 HCV core to RXRA/PPARA-mediated transcription
  - N00530 HCV core to RXRA/LXRA-mediated transcription