# Small cell lung cancer - Reference pathway

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- nt06214 PI3K signaling
  - N00051 Deleted PTEN to PI3K signaling pathway
  - N00052 Mutation-inactivated PTEN to PI3K signaling pathway
- nt06230 Cell cycle
  - N00074 Loss of RB1 to cell cycle G1/S
  - N00075 Mutation-inactivated RB1 to cell cycle G1/S
  - N00088 Amplified MYC to p15-cell cycle G1/S
  - N00089 Amplified MYC to cell cycle G1/S
  - N00092 Amplified MYC to p27-cell cycle G1/S
- nt06231 Apoptosis
  - N00100 BCL2-overexpression to intrinsic apoptotic pathway
- nt06240 Transcription
  - N00115 Mutation-inactivated TP53 to transcription