# Chronic myeloid leukemia - Reference pathway

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- nt06210 ERK signaling
  - N00002 BCR-ABL fusion kinase to RAS-ERK signaling pathway
- nt06214 PI3K signaling
  - N00048 BCR-ABL fusion kinase to PI3K signaling pathway
- nt06218 TGFB signaling
  - N00106 AML1-EVI1 fusion to TGF-beta signaling pathway
  - N00107 EVI-1 overexpression to TGF-beta signaling pathway
- nt06219 JAK-STAT signaling
  - N00055 BCR-ABL fusion kinase to Jak-STAT signaling pathway
- nt06230 Cell cycle
  - N00067 Deleted p14(ARF) to p21-cell cycle G1/S
  - N00070 Mutation-inactivated p16(INK4a) to p16-cell cycle G1/S
  - N00074 Loss of RB1 to cell cycle G1/S
- nt06240 Transcription
  - N00115 Mutation-inactivated TP53 to transcription