# Coronavirus disease - COVID-19 - Reference pathway

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- nt06133 RLR signaling (viruses)
  - N01310 SARS-CoV-2 nsp13 to RIG-I-IRF7/3 signaling pathway
  - N01320 SARS-CoV-2 nsp3 to RIG-I-IRF7/3 signaling pathway
  - N01319 SARS-CoV-2 nsp6 and ORF6 to RIG-I-IRF7/3 signaling pathway
  - N01309 SARS-CoV-2 nsp3 to MDA5-IRF7/3 signaling pathway
- nt06136 Complement activation (viruses)
  - N01312 SARS-CoV-2 S to lectin pathway of complement activation
  - N01314 SARS-CoV-2 S to classical pathway of complement activation
  - N01316 SARS-CoV-2 S/N to lectin pathway of coagulation activation
- nt06122 IFN signaling (viruses)
  - N01321 SARS-CoV-2 nsp1/6/13, ORF3a/6/7b and M to IFN signaling pathway
  - N01322 SARS-CoV-2 nsp6/13 and ORF7a/7b to IFN signaling pathway
- nt06141 Translation (viruses)
  - N01318 SARS-CoV-2 nsp1 to translation initiation
- nt06171 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
  - N01307 SARS-CoV-2 S to AngII-AT1R-NOX2 signaling pathway