# Gastric cancer - Reference pathway

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- nt06210 ERK signaling
  - N00252 Amplified ERBB2 to RAS-ERK signaling pathway
  - N00020 Amplified FGFR to RAS-ERK signaling pathway
  - N00259 Amplified MET to RAS-ERK signaling pathway
  - N00012 Mutation-activated KRAS/NRAS to ERK signaling pathway
- nt06214 PI3K signaling
  - N00253 Amplified ERBB2 to PI3K signaling pathway
  - N00038 Amplified FGFR to PI3K signaling pathway
  - N00260 Amplified MET to PI3K signaling pathway
- nt06215 WNT signaling
  - N00057 Mutation-inactivated APC to Wnt signaling pathway
  - N00257 Loss of CDH1 to beta-catenin signaling pathway
  - N00258 Mutation-inactivated CDH1 to beta-catenin signaling pathway
- nt06218 TGFB signaling
  - N00256 TGFBR1-reduced expression to TGF-beta signaling pathway
- nt06230 Cell cycle
  - N00254 CDKN1B-reduced expression to p27-cell cycle G1/S
  - N00255 Amplified CCNE to cell cycle G1/S
- nt06232 Telomerase activity
  - N00240 TERT-overexpression to telomerase activity
- nt06240 Transcription
  - N00115 Mutation-inactivated TP53 to transcription
  - N00250 CDX2-overexpression to transcriptional activation
  - N00251 CDX2-overexpression to transcriptional repression