{"text_format":"3","workbook":"xls","n_sheets":1,"sheets":["Table S2"],"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"Table S2","index":0,"n_rows":31,"n_cols":255,"rows_kept":31,"merged":[[0,0,0,255]],"flags":["formulas_cached_only"]}
["The annotation of 16 immune cells and 13 functions in ssGSEA"]
["Immune cells and functions","Genes related to the immune cells and functions"]
["aDCs","CD83","LAMP3","CCL1"]
["B_cells","BACH2","BANK1","BLK","BTLA","CD79A","CD79B","FCRL1","FCRL3","HVCN1","RALGPS2"]
["CD8+_T_cells","CD8A"]
["DCs","CCL17","CCL22","CD209","CCL13"]
["iDCs","CD1A","CD1E"]
["Macrophages","C11orf45","CD68","CLEC5A","CYBB","FUCA1","GPNMB","HS3ST2","LGMN","MMP9","TM4SF19"]
["Mast_cells","CMA1","MS4A2","TPSAB1"]
["Neutrophils","EVI2B","HSD17B11","KDM6B","MEGF9","MNDA","NLRP12","PADI4","SELL","TRANK1","VNN3"]
["NK_cells","KLRC1","KLRF1"]
["pDCs","CLEC4C","CXCR3","GZMB","IL3RA","IRF7","IRF8","LILRA4","PHEX","PLD4","PTCRA"]
["T_helper_cells","CD4"]
["Tfh","PDCD1","CXCL13","CXCR5"]
["Th1_cells","IFNG","TBX21","CTLA4","STAT4","CD38","IL12RB2","LTA","CSF2"]
["Th2_cells","PMCH","LAIR2","SMAD2","CXCR6","GATA3","IL26"]
["TIL","ITM2C","CD38","THEMIS2","GLYR1","ICOS","F5","TIGIT","KLRD1","IRF4","PRKCQ","FCRL5","SIRPG","LPXN","IL2RG","CCL5","LCK","TRAF3IP3","CD86","MAL","LILRB1","DOK2","CD6","PAG1","LAX1","PLEK","PIK3CD","SLAMF1","XCL1","GPR171","XCL2","TBX21","CD2","CD53","KLHL6","SLAMF6","CD40","SIT1","TNFRSF4","CD79A","CD247","LCP2","CD3D","CD27","SH2D1A","FYB","ARHGAP30","ACAP1","CST7","CD3G","IL2RB","CD3E","FCRL3","CORO1A","ITK","TCL1A","CYBB","CSF2RB","IKZF1","NCF4","DOCK2","CCR2","PTPRC","PLAC8","NCKAP1L","IL7R","2020-09-06","CD28","STAT4","CD8A","LY9","CD48","HCST","PTPRCAP","SASH3","ARHGAP25","LAT","TRAT1","IL10RA","PAX5","CCR7","DOCK11","PARVG","SPNS1","CD52","HCLS1","ARHGAP9","GIMAP6","PRKCB","MS4A1","GPR18","TBC1D10C","GVINP1","P2RY8","EVI2B","VAMP5","KLRK1","SELL","MPEG1","MS4A6A","ARHGAP15","MFNG","GZMK","SELPLG","TARP","GIMAP7","FAM65B","INPP5D","ITGA4","MZB1","GPSM3","STK10","CLEC2D","IL16","NLRC3","GIMAP5","GIMAP4","IFFO1","CFH","PVRIG","CFHR1"]
["Treg","IL12RB2","TMPRSS6","CTSC","LAPTM4B","TFRC","RNF145","NETO2","ADAT2","CHST2","CTLA4","NFE2L3","LIMA1","IL1R2","ICOS","HSDL2","HTATIP2","FKBP1A","TIGIT","CCR8","LTA","SLC35F2","IL21R","AHCYL1","SOCS2","ETV7","BCL2L1","RRAGB","ACSL4","CHRNA6","BATF","LAX1","ADPRH","TNFRSF4","ANKRD10","CD274","CASP1","LY75","NPTN","SSTR3","GRSF1","CSF2RB","TMEM184C","NDFIP2","ZBTB38","ERI1","TRAF3","NAB1","HS3ST3B1","LAYN","JAK1","VDR","LEPROT","GCNT1","PTPRJ","IKZF2","CSF1","ENTPD1","TNFRSF18","METTL7A","KSR1","SSH1","CADM1","IL1R1","ACP5","CHST7","THADA","CD177","NFAT5","ZNF282","MAGEH1"]
["APC_co_inhibition","C10orf54","CD274","LGALS9","PDCD1LG2","PVRL3"]
["APC_co_stimulation","CD40","CD58","CD70","ICOSLG","SLAMF1","TNFSF14","TNFSF15","TNFSF18","TNFSF4","TNFSF8","TNFSF9"]
["CCR","CCL16","TPO","TGFBR2","CXCL2","CCL14","TGFBR3","IL11RA","CCL11","IL4I1","IL33","CXCL12","CXCL10","BMPER","BMP8A","CXCL11","IL21R","IL17B","TNFRSF9","ILF2","CX3CR1","CCR8","TNFSF12","CSF3","TNFSF4","BMP3","CX3CL1","BMP5","CXCR2","TNFRSF10D","BMP2","CXCL14","CCL28","CXCL3","BMP6","CCL21","CXCL9","CCL23","IL6","TNFRSF18","IL17RD","IL17D","IL27","CCL7","IL1R1","CXCR4","CXCR2P1","TGFB1I1","IFNGR1","IL9R","IL1RAPL1","IL11","CSF1","IL20RA","IL25","TNFRSF4","IL18","ILF3","CCL20","TNFRSF12A","IL6ST","CXCL13","IL12B","TNFRSF8","IL6R","BMPR2","IFNE","IL1RAPL2","IL3RA","BMP4","CCL24","TNFSF13B","CCR4","IL2RA","IL32","TNFRSF10C","IL22RA1","BMPR1A","CXCR5","CXCR3","IFNA8","IL17REL","IFNB1","IFNAR1","TNFRSF1B","CCL17","IFNL1","IL16","IL1RL1","ILK","CCL25","ILDR2","CXCR1","IL36RN","IL34","TGFB1","IFNG","IL19","ILKAP","BMP2K","CCR10","ILDR1","EPO","CCR7","IL17C","IL23A","CCR5","IL7","EPOR","CCL13","IL2RG","IL31RA","TNFAIP6","IFNL2","BMP1","IL12RB1","TNFAIP8","IL4R","TNFRSF6B","TNFAIP8L1","TNFRSF10B","IFNL3","CCL5","CXCL6","CXCL1","CCR3","TNFSF11","CSF1R","IL21","IL1RAP","IL12RB2","CCL1","IL17RA","CCR1","IL1RN","TNFRSF11B","TNFRSF14","IL13","IL2RB","BMP8B","CCL2","IL24","IL18RAP","TGFBI","TNFSF10","TNFRSF11A","CXCL5","IL5RA","TNFSF9","IL1RL2","TNFRSF13C","IL36G","IL15RA","TNFRSF21","CXCL8","IL22RA2","TNFAIP8L2","IL18R1","IFNLR1","CXCR6","CCL3L3","TNFRSF1A","IL17RE","IFNGR2","IL17RC","TNFAIP8L3","ILVBL","TGFBRAP1","CCL4L1","CSF2RA","CCRN4L","CCL26","TNFAIP1","CCRL2","IFNA10","TNFRSF17","IFNA13","IL20","IL18BP","CCL3L1","TNFSF12-TNFSF13","IL5","IL23R","IL26","TNF","TGFA","CSF2","IL1F10","CXCL17","TNFSF13","IFNA4","IL37","IL12A","IL7R","IFNA1","IL1A","IL4","IL2","CCL22","CSF3R","IL10","IFNK","TGFB2","IL1R2","IL1B","IL17F","IL27RA","IL15","TNFSF8","IL36B","XCL1","CXCL16","TNFRSF19","IL3","CCL3","IFNA2","BMPR1B","IFNA21","TNFSF18","CCL8","IL17RB","TNFRSF25","IL22","IL10RB","IFNAR2","CCL18","IFNA16","CSF2RB","IL36A","TNFAIP3","IL13RA2","IL13RA1","CCR9","TNFRSF10A","IFNA7","IFNW1","XCL2","TNFSF14","CCR2","BMP15","BMP10","CCL15-CCL14","TGFBR1","IFNA5","BMP7","IFNA14","IL20RB","IL10RA","IFNA17","CCR6","TGFB3","CCL15","CCL4","CCL27","TNFRSF13B"]
["Check-point","IDO1","LAG3","CTLA4","TNFRSF9","ICOS","CD80","PDCD1LG2","TIGIT","CD70","TNFSF9","ICOSLG","KIR3DL1","CD86","PDCD1","LAIR1","TNFRSF8","TNFSF15","TNFRSF14","IDO2","CD276","CD40","TNFRSF4","TNFSF14","HHLA2","CD244","CD274","HAVCR2","CD27","BTLA","LGALS9","TMIGD2","CD28","CD48","TNFRSF25","CD40LG","ADORA2A","VTCN1","CD160","CD44","TNFSF18","TNFRSF18","BTNL2","C10orf54","CD200R1","TNFSF4","CD200","NRP1"]
["Cytolytic_activity","PRF1","GZMA"]
["HLA","HLA-E","HLA-DPB2","HLA-C","HLA-J","HLA-DQB1","HLA-DQB2","HLA-DQA2","HLA-DQA1","HLA-A","HLA-DMA","HLA-DOB","HLA-DRB1","HLA-H","HLA-B","HLA-DRB5","HLA-DOA","HLA-DPB1","HLA-DRA","HLA-DRB6","HLA-L","HLA-F","HLA-G","HLA-DMB","HLA-DPA1"]
["Inflammation-promoting","CCL5","CD19","CD8B","CXCL10","CXCL13","CXCL9","GNLY","GZMB","IFNG","IL12A","IL12B","IRF1","PRF1","STAT1","TBX21"]
["MHC_class_I","B2M","HLA-A","TAP1"]
["Parainflammation","CXCL10","PLAT","CCND1","LGMN","PLAUR","AIM2","MMP7","ICAM1","MX2","CXCL9","ANXA1","TLR2","PLA2G2D","ITGA2","MX1","HMOX1","CD276","TIRAP","IL33","PTGES","TNFRSF12A","SCARB1","CD14","BLNK","IFIT3","RETNLB","IFIT2","ISG15","OAS2","REL","OAS3","CD44","PPARG","BST2","OAS1","NOX1","PLA2G2A","IFIT1","IFITM3","IL1RN"]
["T_cell_co-inhibition","BTLA","C10orf54","CD160","CD244","CD274","CTLA4","HAVCR2","LAG3","LAIR1","TIGIT"]
["T_cell_co-stimulation","CD2","CD226","CD27","CD28","CD40LG","ICOS","SLAMF1","TNFRSF18","TNFRSF25","TNFRSF4","TNFRSF8","TNFRSF9","TNFSF14"]
["Type_I_IFN_Reponse","DDX4","IFIT1","IFIT2","IFIT3","IRF7","ISG20","MX1","MX2","RSAD2","TNFSF10"]
["Type_II_IFN_Reponse","GPR146","SELP","AHR"]