| ONTOLOGY |
ID |
Description |
GeneRatio |
BgRatio |
pvalue |
p.adjust |
qvalue |
geneID |
Count |
| BP |
GO:0030098 |
lymphocyte differentiation |
50/364 |
419/18903 |
2.33E-25 |
8.99E-22 |
7.23E-22 |
CD80/HLA-DRA/SLAMF8/ZBTB16/BATF/IL10/IL6/SLAMF6/IL2RA/SLAMF1/IL7R/CRTAM/PLA2G2D/ITGA4/CTLA4/CD2/IFNG/CR1/IL2RG/CD3D/CLEC4D/CCR2/IL4I1/RASGRP1/IKZF3/RHOH/LY9/ITK/FCRL3/IL1B/THEMIS/CD79A/KLRC1/IRF4/CCR7/GPR18/CD3G/CR2/EOMES/MS4A1/IFNE/LCK/CLEC4E/CD27/POU2AF1/CCL19/CD19/LEP/PAX5/PCK1 |
50 |
| BP |
GO:1903131 |
mononuclear cell differentiation |
52/364 |
473/18903 |
1.16E-24 |
2.24E-21 |
1.80E-21 |
CD80/HLA-DRA/SLAMF8/ZBTB16/BATF/IL10/IL6/SLAMF6/UBD/IL2RA/SLAMF1/IL7R/CRTAM/PLA2G2D/ITGA4/CTLA4/CD2/IFNG/CR1/IL2RG/CD3D/CLEC4D/CCR2/IL4I1/RASGRP1/IKZF3/RHOH/LY9/ITK/FCRL3/IL1B/THEMIS/CD79A/KLRC1/IRF4/CCR7/GPR18/CD3G/CR2/EOMES/MS4A1/IFNE/LCK/CLEC4E/CD27/POU2AF1/CCL19/MT1G/CD19/LEP/PAX5/PCK1 |
52 |
| BP |
GO:0030595 |
leukocyte chemotaxis |
37/364 |
240/18903 |
7.46E-23 |
8.37E-20 |
6.73E-20 |
CXCL6/CCL4/CH25H/CCL18/LBP/CXCL1/CCL3/SLAMF8/CCR5/CXCL13/CXCL3/IL10/CXCR4/IL6/SLAMF1/CCL7/CXCL10/CCL8/CXCL2/PLA2G7/S100A9/TNFAIP6/CCR2/CXCL11/CXCL9/XCL2/XCL1/IL1B/CCR7/GPR18/CCL13/S100A8/STAP1/FPR2/CCL19/CCL20/CNR2 |
37 |
| BP |
GO:0050900 |
leukocyte migration |
46/364 |
398/18903 |
8.69E-23 |
8.37E-20 |
6.73E-20 |
CXCL6/CCL4/CH25H/CCL18/LBP/CXCL1/CCL3/SLAMF8/CCR5/CXCL13/CXCL3/IL10/CXCR4/IL6/SELE/SLAMF1/CRTAM/CCL7/CXCL10/ITGA4/CCL8/CXCL2/PLA2G7/S100A9/TNFAIP6/CCR2/GCSAM/CXCL11/CXCL9/XCL2/XCL1/RHOH/IL1B/CCR7/GPR18/CCL13/S100A8/STAP1/LCK/FPR2/CCL19/BMP5/APOD/CCL20/CNR2/LEP |
46 |
| BP |
GO:0070098 |
chemokine-mediated signaling pathway |
24/364 |
90/18903 |
4.39E-21 |
3.38E-18 |
2.72E-18 |
CXCL6/CCL4/CCL18/CXCL1/CCL3/CCR5/CXCL13/CXCL3/CXCR4/CCL7/CXCL10/CCL8/CCR4/CXCL2/CXCR6/CCR2/CXCL11/CXCL9/XCL2/XCL1/CCR7/CCL13/CCL19/CCL20 |
24 |
| BP |
GO:0030217 |
T cell differentiation |
38/364 |
296/18903 |
1.45E-20 |
9.29E-18 |
7.47E-18 |
CD80/HLA-DRA/ZBTB16/BATF/IL6/SLAMF6/IL2RA/IL7R/CRTAM/PLA2G2D/CTLA4/CD2/IFNG/CR1/IL2RG/CD3D/CLEC4D/CCR2/IL4I1/RASGRP1/IKZF3/RHOH/LY9/ITK/IL1B/THEMIS/KLRC1/IRF4/CCR7/GPR18/CD3G/EOMES/LCK/CLEC4E/CD27/CCL19/LEP/PCK1 |
38 |
| BP |
GO:0019221 |
cytokine-mediated signaling pathway |
48/364 |
496/18903 |
1.96E-20 |
1.08E-17 |
8.66E-18 |
CXCL6/CCL4/CCL18/CXCL1/CCL3/CCR5/IL21R/AIM2/CXCL13/CXCL3/CXCR4/IL6/CD300LF/IL2RA/IL7R/CCL7/CXCL10/OSM/CNTFR/IFNG/CCL8/CCR4/CXCL2/IL2RG/BIRC3/CXCR6/CCR2/CXCL11/CXCL9/LILRA3/NLRP2/XCL2/XCL1/MMP12/IL1B/ZBP1/TNFRSF17/CCR7/CCL13/LILRA4/STAP1/IFNE/CCL19/DUOX2/IL1RN/CCL20/LEP/ADIPOQ |
48 |
| BP |
GO:0060326 |
cell chemotaxis |
39/364 |
319/18903 |
2.59E-20 |
1.24E-17 |
1.00E-17 |
CXCL6/CCL4/CH25H/CCL18/LBP/CXCL1/CCL3/SLAMF8/CCR5/CXCL13/CXCL3/IL10/CXCR4/IL6/SLAMF1/CCL7/CXCL10/CCL8/CCR4/CXCL2/CXCR6/PLA2G7/S100A9/TNFAIP6/CCR2/CXCL11/CXCL9/XCL2/XCL1/IL1B/CCR7/GPR18/CCL13/S100A8/STAP1/FPR2/CCL19/CCL20/CNR2 |
39 |
| BP |
GO:1990868 |
response to chemokine |
24/364 |
98/18903 |
3.99E-20 |
1.53E-17 |
1.23E-17 |
CXCL6/CCL4/CCL18/CXCL1/CCL3/CCR5/CXCL13/CXCL3/CXCR4/CCL7/CXCL10/CCL8/CCR4/CXCL2/CXCR6/CCR2/CXCL11/CXCL9/XCL2/XCL1/CCR7/CCL13/CCL19/CCL20 |
24 |
| BP |
GO:1990869 |
cellular response to chemokine |
24/364 |
98/18903 |
3.99E-20 |
1.53E-17 |
1.23E-17 |
CXCL6/CCL4/CCL18/CXCL1/CCL3/CCR5/CXCL13/CXCL3/CXCR4/CCL7/CXCL10/CCL8/CCR4/CXCL2/CXCR6/CCR2/CXCL11/CXCL9/XCL2/XCL1/CCR7/CCL13/CCL19/CCL20 |
24 |
| BP |
GO:0002449 |
lymphocyte mediated immunity |
41/364 |
367/18903 |
7.68E-20 |
2.69E-17 |
2.16E-17 |
FCGR1A/HLA-DQA1/HLA-DRA/IL21R/FCGR3A/BATF/IL10/IL6/SLAMF6/SLAMF7/SLAMF1/IL7R/CRTAM/CD2/CR1/TLR8/KLRB1/HLA-DOB/CCR2/IGHG1/IL4I1/CD96/XCL1/RASGRP1/GZMB/CLNK/TRA/IGLL5/IL1B/GAPT/KLRC1/CR2/CD27/HLA-DQB2/IGHE/CD19/C6/LEP/IGHD/AZGP1/KDM5D |
41 |
| BP |
GO:1990266 |
neutrophil migration |
26/364 |
130/18903 |
2.60E-19 |
8.34E-17 |
6.71E-17 |
CXCL6/CCL4/CCL18/LBP/CXCL1/CCL3/SLAMF8/CXCL13/CXCL3/CCL7/CXCL10/CCL8/CXCL2/S100A9/TNFAIP6/CXCL11/CXCL9/XCL2/XCL1/RHOH/IL1B/CCR7/CCL13/S100A8/CCL19/CCL20 |
26 |
| BP |
GO:0030593 |
neutrophil chemotaxis |
24/364 |
106/18903 |
2.93E-19 |
8.69E-17 |
6.99E-17 |
CXCL6/CCL4/CCL18/LBP/CXCL1/CCL3/CXCL13/CXCL3/CCL7/CXCL10/CCL8/CXCL2/S100A9/TNFAIP6/CXCL11/CXCL9/XCL2/XCL1/IL1B/CCR7/CCL13/S100A8/CCL19/CCL20 |
24 |
| BP |
GO:0007159 |
leukocyte cell-cell adhesion |
42/364 |
414/18903 |
9.92E-19 |
2.73E-16 |
2.19E-16 |
SLC39A8/HLA-DQA1/CD80/HLA-DRA/ZBTB16/IL10/IL6/SELE/IL2RA/SLAMF1/IL7R/CRTAM/ICOS/PLA2G2D/ITGA4/CTLA4/IFNG/CR1/IL2RG/TIGIT/S100A9/IDO1/HLA-DOB/CCR2/IL4I1/LAX1/CD274/XCL1/RASGRP1/SIRPG/RHOH/IL1B/CCR7/S100A8/LCK/CD27/OLR1/HLA-DQB2/CCL19/IGF2/LEP/PCK1 |
42 |
| BP |
GO:0050863 |
regulation of T cell activation |
40/364 |
376/18903 |
1.30E-18 |
3.33E-16 |
2.68E-16 |
HLA-DQA1/CD80/HLA-DRA/ZBTB16/BATF/IL10/IL6/IL2RA/SLAMF1/IL7R/CRTAM/ICOS/PLA2G2D/CTLA4/CD2/IFNG/CR1/IL2RG/TIGIT/IDO1/HLA-DOB/CCR2/IL4I1/LAX1/CD274/XCL1/RASGRP1/SIRPG/RHOH/IL1B/IRF4/CCR7/SIT1/LCK/CD27/HLA-DQB2/CCL19/IGF2/LEP/PCK1 |
40 |
| BP |
GO:0002443 |
leukocyte mediated immunity |
44/364 |
463/18903 |
1.73E-18 |
4.17E-16 |
3.35E-16 |
CXCL6/FCGR1A/HLA-DQA1/HLA-DRA/CCL3/IL21R/FCGR3A/BATF/IL10/IL6/SLAMF6/SLAMF7/SLAMF1/IL7R/CRTAM/CD2/CR1/TLR8/KLRB1/HLA-DOB/CCR2/IGHG1/IL4I1/CD96/XCL1/RASGRP1/GZMB/CLNK/TRA/IGLL5/IL1B/GAPT/KLRC1/CR2/STAP1/CD27/HLA-DQB2/IGHE/CD19/C6/LEP/IGHD/AZGP1/KDM5D |
44 |
| BP |
GO:0071621 |
granulocyte chemotaxis |
25/364 |
130/18903 |
3.51E-18 |
7.96E-16 |
6.40E-16 |
CXCL6/CCL4/CCL18/LBP/CXCL1/CCL3/CXCL13/CXCL3/SLAMF1/CCL7/CXCL10/CCL8/CXCL2/S100A9/TNFAIP6/CXCL11/CXCL9/XCL2/XCL1/IL1B/CCR7/CCL13/S100A8/CCL19/CCL20 |
25 |
| BP |
GO:0097530 |
granulocyte migration |
27/364 |
158/18903 |
3.76E-18 |
8.05E-16 |
6.47E-16 |
CXCL6/CCL4/CCL18/LBP/CXCL1/CCL3/SLAMF8/CXCL13/CXCL3/SLAMF1/CCL7/CXCL10/CCL8/CXCL2/S100A9/TNFAIP6/CXCL11/CXCL9/XCL2/XCL1/RHOH/IL1B/CCR7/CCL13/S100A8/CCL19/CCL20 |
27 |
| BP |
GO:0097529 |
myeloid leukocyte migration |
32/364 |
242/18903 |
7.30E-18 |
1.48E-15 |
1.19E-15 |
CXCL6/CCL4/CCL18/LBP/CXCL1/CCL3/SLAMF8/CXCL13/CXCL3/IL6/SLAMF1/CCL7/CXCL10/CCL8/CXCL2/PLA2G7/S100A9/TNFAIP6/CCR2/CXCL11/CXCL9/XCL2/XCL1/RHOH/IL1B/CCR7/CCL13/S100A8/STAP1/FPR2/CCL19/CCL20 |
32 |
| BP |
GO:0002460 |
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains |
39/364 |
375/18903 |
7.91E-18 |
1.52E-15 |
1.22E-15 |
FCGR1A/HLA-DQA1/CD80/HLA-DRA/IL21R/FCGR3A/CXCL13/BATF/IL10/IL6/SLAMF6/SLAMF1/IL7R/CR1/TLR8/HLA-DOB/CCR2/IGHG1/IL4I1/CD274/XCL1/LY9/TRA/IGLL5/IL1B/GAPT/KLRC1/IRF4/CLEC6A/CR2/CD27/HLA-DQB2/CCL19/IGHE/CD19/C6/IGHD/AZGP1/KDM5D |
39 |
| BP |
GO:0032103 |
positive regulation of response to external stimulus |
43/364 |
464/18903 |
1.12E-17 |
2.05E-15 |
1.65E-15 |
FCGR1A/CCL4/LBP/CCL3/CD180/AIM2/CXCL13/CXCR4/IL6/SLAMF6/SLAMF1/CRTAM/CCL7/CXCL10/OSM/IFNG/TLR8/CCR4/PLA2G7/S100A9/IDO1/GBP5/CCR2/XCL2/XCL1/RASGRP1/MMP12/TLR10/CLNK/IL1B/ZBP1/CCR7/CLEC6A/S100A8/STAP1/PYHIN1/FCN1/LGALS2/FPR2/CCL19/MIAT/FABP4/NEAT1 |
43 |
| BP |
GO:0002696 |
positive regulation of leukocyte activation |
42/364 |
450/18903 |
2.12E-17 |
3.72E-15 |
2.99E-15 |
LBP/HLA-DQA1/CD80/HLA-DRA/CCL3/FCGR3A/ZBTB16/IL10/IL6/IL2RA/SLAMF1/IL7R/ICOS/CD2/IFNG/CR1/CD38/IL2RG/CLEC4D/HLA-DOB/CCR2/IGHG1/IL4I1/CD274/XCL1/RASGRP1/SIRPG/RHOH/IGLL5/FCRL3/IL1B/CCR7/STAP1/LCK/CD27/HLA-DQB2/CCL19/IGHE/IGF2/LEP/IGHD/PCK1 |
42 |
| BP |
GO:1903037 |
regulation of leukocyte cell-cell adhesion |
38/364 |
377/18903 |
6.14E-17 |
1.03E-14 |
8.27E-15 |
HLA-DQA1/CD80/HLA-DRA/ZBTB16/IL10/IL6/SELE/IL2RA/SLAMF1/IL7R/CRTAM/ICOS/PLA2G2D/ITGA4/CTLA4/IFNG/CR1/IL2RG/TIGIT/IDO1/HLA-DOB/CCR2/IL4I1/LAX1/CD274/XCL1/RASGRP1/SIRPG/RHOH/IL1B/CCR7/LCK/CD27/HLA-DQB2/CCL19/IGF2/LEP/PCK1 |
38 |
| BP |
GO:0050867 |
positive regulation of cell activation |
42/364 |
467/18903 |
8.12E-17 |
1.30E-14 |
1.05E-14 |
LBP/HLA-DQA1/CD80/HLA-DRA/CCL3/FCGR3A/ZBTB16/IL10/IL6/IL2RA/SLAMF1/IL7R/ICOS/CD2/IFNG/CR1/CD38/IL2RG/CLEC4D/HLA-DOB/CCR2/IGHG1/IL4I1/CD274/XCL1/RASGRP1/SIRPG/RHOH/IGLL5/FCRL3/IL1B/CCR7/STAP1/LCK/CD27/HLA-DQB2/CCL19/IGHE/IGF2/LEP/IGHD/PCK1 |
42 |
| BP |
GO:0071674 |
mononuclear cell migration |
28/364 |
206/18903 |
4.36E-16 |
6.71E-14 |
5.40E-14 |
CCL4/CH25H/CCL18/CCL3/SLAMF8/CCR5/CXCL13/CXCR4/IL6/SLAMF1/CRTAM/CCL7/CXCL10/ITGA4/CCL8/PLA2G7/CCR2/GCSAM/CXCL11/XCL2/XCL1/CCR7/CCL13/FPR2/CCL19/BMP5/APOD/CCL20 |
28 |
| BP |
GO:0002768 |
immune response-regulating cell surface receptor signaling pathway |
35/364 |
341/18903 |
6.35E-16 |
9.40E-14 |
7.56E-14 |
FCGR1A/FCGR3A/CTLA4/CR1/FPR1/CD38/CD3D/BTLA/TRAT1/CLEC4D/GCSAM/IGHG1/LAX1/ITK/IGLL5/FCRL3/THEMIS/CD79A/KLRC1/CCR7/CLEC6A/CD3G/CR2/LILRA4/MS4A1/STAP1/LCK/CLEC4E/FCN1/TRAC/FPR2/TRGC2/IGHE/CD19/IGHD |
35 |
| BP |
GO:0001819 |
positive regulation of cytokine production |
41/364 |
486/18903 |
1.80E-15 |
2.57E-13 |
2.06E-13 |
LBP/CD80/CCL3/AIM2/FCGR3A/BATF/IL10/IL6/SLAMF6/CHI3L1/SLAMF1/CRTAM/WNT11/CD2/OSM/IFNG/TLR8/TIGIT/IDO1/GBP5/CCR2/NLRP2/CD274/XCL1/RASGRP1/MMP12/LY9/ITK/CLNK/IL1B/IRF4/CCR7/CLEC6A/PYHIN1/CLEC4E/FCN1/POU2AF1/CCL19/LEP/IGHD/ADIPOQ |
41 |
| BP |
GO:1903039 |
positive regulation of leukocyte cell-cell adhesion |
31/364 |
275/18903 |
2.33E-15 |
3.17E-13 |
2.55E-13 |
HLA-DQA1/CD80/HLA-DRA/ZBTB16/IL6/SELE/IL2RA/SLAMF1/IL7R/ICOS/ITGA4/IFNG/CR1/IL2RG/HLA-DOB/CCR2/IL4I1/CD274/XCL1/RASGRP1/SIRPG/RHOH/IL1B/CCR7/LCK/CD27/HLA-DQB2/CCL19/IGF2/LEP/PCK1 |
31 |
| BP |
GO:0022407 |
regulation of cell-cell adhesion |
41/364 |
490/18903 |
2.39E-15 |
3.17E-13 |
2.55E-13 |
HLA-DQA1/CD80/HLA-DRA/CXCL13/ZBTB16/IL10/IL6/SELE/IL2RA/SLAMF1/IL7R/CRTAM/ICOS/PLA2G2D/ITGA4/CTLA4/IFNG/CR1/IL2RG/TIGIT/IDO1/HLA-DOB/CCR2/IL4I1/LAX1/CD274/XCL1/RASGRP1/SIRPG/RHOH/IL1B/CCR7/LCK/CD27/HLA-DQB2/CCL19/IGF2/IL1RN/LEP/ADIPOQ/PCK1 |
41 |
| BP |
GO:0051251 |
positive regulation of lymphocyte activation |
37/364 |
400/18903 |
2.58E-15 |
3.31E-13 |
2.66E-13 |
HLA-DQA1/CD80/HLA-DRA/FCGR3A/ZBTB16/IL10/IL6/IL2RA/SLAMF1/IL7R/ICOS/IFNG/CR1/CD38/IL2RG/HLA-DOB/CCR2/IGHG1/IL4I1/CD274/XCL1/RASGRP1/SIRPG/RHOH/IGLL5/FCRL3/IL1B/CCR7/LCK/CD27/HLA-DQB2/CCL19/IGHE/IGF2/LEP/IGHD/PCK1 |
37 |
| BP |
GO:0022409 |
positive regulation of cell-cell adhesion |
33/364 |
322/18903 |
4.68E-15 |
5.81E-13 |
4.67E-13 |
HLA-DQA1/CD80/HLA-DRA/CXCL13/ZBTB16/IL10/IL6/SELE/IL2RA/SLAMF1/IL7R/ICOS/ITGA4/IFNG/CR1/IL2RG/HLA-DOB/CCR2/IL4I1/CD274/XCL1/RASGRP1/SIRPG/RHOH/IL1B/CCR7/LCK/CD27/HLA-DQB2/CCL19/IGF2/LEP/PCK1 |
33 |
| BP |
GO:0046651 |
lymphocyte proliferation |
32/364 |
305/18903 |
6.37E-15 |
7.66E-13 |
6.16E-13 |
CD80/CD180/FCGR3A/IL10/IL6/IL2RA/SLAMF1/IL7R/CRTAM/PLA2G2D/CTLA4/CR1/CD38/IDO1/CCR2/MZB1/IL4I1/CD274/XCL1/RASGRP1/IKZF3/FCRL3/IL1B/CD79A/GAPT/CR2/MS4A1/IFNE/CCL19/IGF2/CD19/LEP |
32 |
| BP |
GO:0031349 |
positive regulation of defense response |
32/364 |
307/18903 |
7.67E-15 |
8.94E-13 |
7.19E-13 |
FCGR1A/LBP/CCL3/AIM2/IL6/SLAMF6/CRTAM/OSM/IFNG/TLR8/PLA2G7/S100A9/IDO1/GBP5/CCR2/RASGRP1/MMP12/TLR10/CLNK/IL1B/ZBP1/CCR7/CLEC6A/S100A8/STAP1/PYHIN1/FCN1/LGALS2/FPR2/MIAT/FABP4/NEAT1 |
32 |
| BP |
GO:0050870 |
positive regulation of T cell activation |
29/364 |
251/18903 |
1.01E-14 |
1.14E-12 |
9.18E-13 |
HLA-DQA1/CD80/HLA-DRA/ZBTB16/IL6/IL2RA/SLAMF1/IL7R/ICOS/IFNG/CR1/IL2RG/HLA-DOB/CCR2/IL4I1/CD274/XCL1/RASGRP1/SIRPG/RHOH/IL1B/CCR7/LCK/CD27/HLA-DQB2/CCL19/IGF2/LEP/PCK1 |
29 |
| BP |
GO:0032943 |
mononuclear cell proliferation |
32/364 |
312/18903 |
1.21E-14 |
1.33E-12 |
1.07E-12 |
CD80/CD180/FCGR3A/IL10/IL6/IL2RA/SLAMF1/IL7R/CRTAM/PLA2G2D/CTLA4/CR1/CD38/IDO1/CCR2/MZB1/IL4I1/CD274/XCL1/RASGRP1/IKZF3/FCRL3/IL1B/CD79A/GAPT/CR2/MS4A1/IFNE/CCL19/IGF2/CD19/LEP |
32 |
| BP |
GO:0050727 |
regulation of inflammatory response |
36/364 |
414/18903 |
4.19E-14 |
4.48E-12 |
3.60E-12 |
MMP3/FCGR1A/LBP/CCL3/SLAMF8/AIM2/IL10/IL6/SELE/IL2RA/SIGLEC10/PLA2G2D/OSM/IFNG/PBK/BIRC3/PLA2G7/S100A9/TNFAIP6/IDO1/CCR2/NLRP2/XCL1/TLR10/IL1B/ZBP1/CCR7/S100A8/SMPDL3B/STAP1/LGALS2/FPR2/CNR2/FABP4/ADIPOQ/NEAT1 |
36 |
| BP |
GO:0070661 |
leukocyte proliferation |
33/364 |
348/18903 |
4.41E-14 |
4.59E-12 |
3.69E-12 |
CD80/CD180/FCGR3A/IL10/IL6/IL2RA/SLAMF1/IL7R/CRTAM/PLA2G2D/CTLA4/CR1/CCL8/CD38/IDO1/CCR2/MZB1/IL4I1/CD274/XCL1/RASGRP1/IKZF3/FCRL3/IL1B/CD79A/GAPT/CR2/MS4A1/IFNE/CCL19/IGF2/CD19/LEP |
33 |
| BP |
GO:0002685 |
regulation of leukocyte migration |
27/364 |
231/18903 |
6.51E-14 |
6.59E-12 |
5.30E-12 |
CCL4/LBP/CCL3/SLAMF8/CXCL13/IL6/SELE/SLAMF1/CCL7/CXCL10/ITGA4/CCL8/PLA2G7/TNFAIP6/CCR2/GCSAM/XCL2/XCL1/RHOH/CCR7/GPR18/STAP1/FPR2/CCL19/BMP5/APOD/CCL20 |
27 |
| BP |
GO:0002697 |
regulation of immune effector process |
34/364 |
379/18903 |
9.02E-14 |
8.90E-12 |
7.16E-12 |
CXCL6/FCGR1A/LBP/CD80/HLA-DRA/SLAMF8/BATF/IL10/IL6/SLAMF6/SLAMF1/IL7R/CRTAM/IFNG/CR1/KLRB1/CCR2/MZB1/IL4I1/CD96/XCL1/RASGRP1/CLNK/FCRL3/IL1B/KLRC1/IRF4/CR2/STAP1/FCN1/CCL19/LEP/AZGP1/PCK1 |
34 |
| BP |
GO:0032496 |
response to lipopolysaccharide |
32/364 |
339/18903 |
1.24E-13 |
1.19E-11 |
9.57E-12 |
CXCL6/KMO/LBP/CXCL1/CD80/CCL3/CD180/CCR5/CXCL13/CXCL3/IL10/IL6/SELE/TNIP3/GJB2/CXCL10/CXCL2/S100A9/NUGGC/PCSK1/IDO1/CXCL11/CXCL9/CD274/CD96/FASLG/IL1B/CCR7/S100A8/STAP1/CNR2/GJB6 |
32 |
| BP |
GO:0072676 |
lymphocyte migration |
20/364 |
124/18903 |
2.84E-13 |
2.67E-11 |
2.14E-11 |
CCL4/CH25H/CCL18/CCL3/CXCL13/CRTAM/CCL7/CXCL10/ITGA4/CCL8/CCR2/GCSAM/CXCL11/XCL2/XCL1/CCR7/CCL13/CCL19/APOD/CCL20 |
20 |
| BP |
GO:0042113 |
B cell activation |
32/364 |
350/18903 |
2.98E-13 |
2.73E-11 |
2.20E-11 |
SAMSN1/CD180/SLAMF8/BATF/IL10/IL6/IL7R/ITGA4/CTLA4/CR1/CD38/IL2RG/MZB1/IGHG1/IL4I1/LAX1/RASGRP1/IKZF3/IGLL5/FCRL3/CD79A/GAPT/CR2/MS4A1/IFNE/CD27/POU2AF1/IGHE/CD19/FCRL1/PAX5/IGHD |
32 |
| BP |
GO:0002548 |
monocyte chemotaxis |
16/364 |
71/18903 |
3.15E-13 |
2.82E-11 |
2.27E-11 |
CCL4/CCL18/CCL3/SLAMF8/IL6/CCL7/CXCL10/CCL8/PLA2G7/CCR2/XCL2/XCL1/CCL13/FPR2/CCL19/CCL20 |
16 |
| BP |
GO:0046631 |
alpha-beta T cell activation |
23/364 |
174/18903 |
3.59E-13 |
3.15E-11 |
2.53E-11 |
CD80/HLA-DRA/ZBTB16/BATF/IL6/SLAMF6/IL2RA/CRTAM/PLA2G2D/IFNG/IL2RG/CD3D/CCR2/CD274/XCL1/LY9/ITK/IRF4/GPR18/CD3G/EOMES/TRAC/CCL19 |
23 |
| BP |
GO:0002683 |
negative regulation of immune system process |
36/364 |
449/18903 |
4.81E-13 |
4.12E-11 |
3.31E-11 |
SAMSN1/CD80/CCL3/SLAMF8/IL10/CD300LF/IL2RA/SLAMF1/IL7R/CRTAM/PLA2G2D/CTLA4/CR1/TIGIT/TNFAIP6/IDO1/HLA-DOB/CCR2/GCSAM/IL4I1/LAX1/CD274/CD96/XCL1/MMP12/CLNK/FCRL3/KLRC1/GPR18/CR2/STAP1/BMP5/APOD/PDCD1/CNR2/ADIPOQ |
36 |
| BP |
GO:0002237 |
response to molecule of bacterial origin |
32/364 |
360/18903 |
6.43E-13 |
5.38E-11 |
4.33E-11 |
CXCL6/KMO/LBP/CXCL1/CD80/CCL3/CD180/CCR5/CXCL13/CXCL3/IL10/IL6/SELE/TNIP3/GJB2/CXCL10/CXCL2/S100A9/NUGGC/PCSK1/IDO1/CXCL11/CXCL9/CD274/CD96/FASLG/IL1B/CCR7/S100A8/STAP1/CNR2/GJB6 |
32 |
| BP |
GO:0048247 |
lymphocyte chemotaxis |
15/364 |
65/18903 |
1.21E-12 |
9.88E-11 |
7.95E-11 |
CCL4/CH25H/CCL18/CCL3/CXCL13/CCL7/CXCL10/CCL8/CCR2/CXCL11/XCL2/XCL1/CCL13/CCL19/CCL20 |
15 |
| BP |
GO:0002253 |
activation of immune response |
33/364 |
397/18903 |
1.77E-12 |
1.42E-10 |
1.14E-10 |
AIM2/CTLA4/CR1/FPR1/CD38/CD3D/TRAT1/GCSAM/IGHG1/LAX1/ITK/IGLL5/FCRL3/IL1B/ZBP1/THEMIS/CD79A/CCR7/CLEC6A/CD3G/CR2/MS4A1/STAP1/PYHIN1/LCK/FCN1/TRAC/FPR2/TRGC2/IGHE/CD19/C6/IGHD |
33 |
| BP |
GO:0045619 |
regulation of lymphocyte differentiation |
24/364 |
210/18903 |
2.72E-12 |
2.14E-10 |
1.72E-10 |
CD80/HLA-DRA/SLAMF8/ZBTB16/BATF/IL10/IL2RA/IL7R/CRTAM/CTLA4/CD2/IFNG/CR1/IL2RG/CCR2/IL4I1/RASGRP1/IKZF3/RHOH/FCRL3/IRF4/CD27/CCL19/PCK1 |
24 |
| BP |
GO:0045785 |
positive regulation of cell adhesion |
36/364 |
484/18903 |
4.35E-12 |
3.35E-10 |
2.70E-10 |
HLA-DQA1/CD80/HLA-DRA/MYOC/CXCL13/ZBTB16/IL10/IL6/SELE/IL2RA/SLAMF1/IL7R/ICOS/ITGA4/IFNG/CR1/IL2RG/TGM2/HLA-DOB/CCR2/IL4I1/CD274/XCL1/RASGRP1/SIRPG/RHOH/IL1B/CCR7/LCK/CD27/HLA-DQB2/CCL19/IGF2/EPB41L4B/LEP/PCK1 |
36 |
| BP |
GO:0002688 |
regulation of leukocyte chemotaxis |
19/364 |
127/18903 |
4.50E-12 |
3.40E-10 |
2.73E-10 |
CCL4/LBP/CCL3/SLAMF8/CXCL13/IL6/SLAMF1/CCL7/CXCL10/PLA2G7/TNFAIP6/CCR2/XCL2/XCL1/CCR7/GPR18/STAP1/FPR2/CCL19 |
19 |
| BP |
GO:0001909 |
leukocyte mediated cytotoxicity |
19/364 |
134/18903 |
1.19E-11 |
8.84E-10 |
7.11E-10 |
CXCL6/FCGR1A/HLA-DRA/FCGR3A/SLAMF6/SLAMF7/IL7R/CRTAM/CD2/KLRB1/IGHG1/XCL1/RASGRP1/GZMB/TRA/KLRC1/STAP1/LEP/AZGP1 |
19 |
| BP |
GO:0002429 |
immune response-activating cell surface receptor signaling pathway |
28/364 |
312/18903 |
1.50E-11 |
1.07E-09 |
8.62E-10 |
CTLA4/CR1/FPR1/CD38/CD3D/TRAT1/GCSAM/IGHG1/LAX1/ITK/IGLL5/FCRL3/THEMIS/CD79A/CCR7/CLEC6A/CD3G/CR2/MS4A1/STAP1/LCK/FCN1/TRAC/FPR2/TRGC2/IGHE/CD19/IGHD |
28 |
| BP |
GO:0002757 |
immune response-activating signal transduction |
28/364 |
312/18903 |
1.50E-11 |
1.07E-09 |
8.62E-10 |
CTLA4/CR1/FPR1/CD38/CD3D/TRAT1/GCSAM/IGHG1/LAX1/ITK/IGLL5/FCRL3/THEMIS/CD79A/CCR7/CLEC6A/CD3G/CR2/MS4A1/STAP1/LCK/FCN1/TRAC/FPR2/TRGC2/IGHE/CD19/IGHD |
28 |
| BP |
GO:0001906 |
cell killing |
22/364 |
189/18903 |
1.57E-11 |
1.10E-09 |
8.81E-10 |
CXCL6/FCGR1A/HLA-DRA/FCGR3A/SLAMF6/SLAMF7/LYZ/IL7R/CRTAM/CD2/IFNG/KLRB1/IGHG1/XCL1/RASGRP1/GZMB/TRA/KLRC1/CCL13/STAP1/LEP/AZGP1 |
22 |
| BP |
GO:0050729 |
positive regulation of inflammatory response |
20/364 |
154/18903 |
1.78E-11 |
1.22E-09 |
9.83E-10 |
FCGR1A/LBP/CCL3/AIM2/IL6/OSM/IFNG/PLA2G7/S100A9/IDO1/CCR2/TLR10/IL1B/ZBP1/CCR7/S100A8/STAP1/LGALS2/FABP4/NEAT1 |
20 |
| BP |
GO:0002366 |
leukocyte activation involved in immune response |
27/364 |
293/18903 |
1.91E-11 |
1.29E-09 |
1.04E-09 |
LBP/CD80/HLA-DRA/CCL3/CD180/FCGR3A/BATF/IL10/IL6/SLAMF6/SLAMF1/IFNG/CR1/CLEC4D/CCR2/RASGRP1/LY9/CLNK/GAPT/IRF4/EOMES/IFNE/CLEC4E/POU2AF1/CCL19/CD19/PCK1 |
27 |
| BP |
GO:0071675 |
regulation of mononuclear cell migration |
18/364 |
123/18903 |
2.43E-11 |
1.61E-09 |
1.30E-09 |
CCL4/CCL3/SLAMF8/CXCL13/SLAMF1/CCL7/CXCL10/ITGA4/PLA2G7/CCR2/GCSAM/XCL2/XCL1/CCR7/FPR2/BMP5/APOD/CCL20 |
18 |
| BP |
GO:0002263 |
cell activation involved in immune response |
27/364 |
297/18903 |
2.61E-11 |
1.70E-09 |
1.37E-09 |
LBP/CD80/HLA-DRA/CCL3/CD180/FCGR3A/BATF/IL10/IL6/SLAMF6/SLAMF1/IFNG/CR1/CLEC4D/CCR2/RASGRP1/LY9/CLNK/GAPT/IRF4/EOMES/IFNE/CLEC4E/POU2AF1/CCL19/CD19/PCK1 |
27 |
| BP |
GO:0070555 |
response to interleukin-1 |
19/364 |
141/18903 |
2.98E-11 |
1.91E-09 |
1.54E-09 |
CCL4/KMO/CCL18/CCL3/IL6/SELE/CHI3L1/CCL7/CCL8/CD38/PCSK1/XCL2/XCL1/IL1B/ZBP1/CCL13/CCL19/IL1RN/CCL20 |
19 |
| BP |
GO:0002706 |
regulation of lymphocyte mediated immunity |
21/364 |
179/18903 |
3.94E-11 |
2.49E-09 |
2.00E-09 |
FCGR1A/HLA-DRA/IL10/IL6/SLAMF6/SLAMF1/IL7R/CRTAM/CR1/KLRB1/CCR2/IL4I1/CD96/XCL1/RASGRP1/CLNK/IL1B/KLRC1/CR2/LEP/AZGP1 |
21 |
| BP |
GO:0071677 |
positive regulation of mononuclear cell migration |
14/364 |
73/18903 |
9.94E-11 |
6.17E-09 |
4.96E-09 |
CCL4/CCL3/CXCL13/SLAMF1/CCL7/CXCL10/ITGA4/PLA2G7/CCR2/XCL2/XCL1/CCR7/FPR2/CCL20 |
14 |
| BP |
GO:1902105 |
regulation of leukocyte differentiation |
27/364 |
317/18903 |
1.16E-10 |
7.07E-09 |
5.69E-09 |
CD80/HLA-DRA/CCL3/SLAMF8/ZBTB16/BATF/IL10/IL2RA/IL7R/CRTAM/CTLA4/CD2/IFNG/CR1/IL2RG/TNFAIP6/CCR2/IL4I1/RASGRP1/IKZF3/RHOH/FCRL3/IRF4/CD27/CCL19/ADIPOQ/PCK1 |
27 |
| BP |
GO:0006959 |
humoral immune response |
27/364 |
320/18903 |
1.43E-10 |
8.62E-09 |
6.93E-09 |
CXCL6/CXCL1/CXCL13/CXCL3/IL6/LYZ/CXCL10/IFNG/CR1/CXCL2/S100A9/IGHG1/CXCL11/CXCL9/IGLL5/IL1B/CCR7/CCL13/CR2/MS4A1/IFNE/FCN1/POU2AF1/IGHE/PDCD1/C6/IGHD |
27 |
| BP |
GO:0050670 |
regulation of lymphocyte proliferation |
23/364 |
239/18903 |
2.62E-10 |
1.55E-08 |
1.24E-08 |
CD80/FCGR3A/IL10/IL6/IL2RA/SLAMF1/CRTAM/PLA2G2D/CTLA4/CR1/CD38/IDO1/CCR2/MZB1/IL4I1/CD274/XCL1/IKZF3/FCRL3/IL1B/CCL19/IGF2/LEP |
23 |
| BP |
GO:0002819 |
regulation of adaptive immune response |
21/364 |
198/18903 |
2.65E-10 |
1.55E-08 |
1.24E-08 |
FCGR1A/SAMSN1/CD80/HLA-DRA/BATF/IL10/IL6/SLAMF1/IL7R/CR1/CD48/CCR2/IL4I1/CD274/XCL1/IL1B/KLRC1/CLEC6A/CR2/CCL19/AZGP1 |
21 |
| BP |
GO:0045580 |
regulation of T cell differentiation |
20/364 |
179/18903 |
2.81E-10 |
1.61E-08 |
1.30E-08 |
CD80/HLA-DRA/ZBTB16/BATF/IL2RA/IL7R/CRTAM/CTLA4/CD2/IFNG/CR1/IL2RG/CCR2/IL4I1/RASGRP1/RHOH/IRF4/CD27/CCL19/PCK1 |
20 |
| BP |
GO:0002703 |
regulation of leukocyte mediated immunity |
23/364 |
241/18903 |
3.09E-10 |
1.75E-08 |
1.41E-08 |
CXCL6/FCGR1A/HLA-DRA/IL10/IL6/SLAMF6/SLAMF1/IL7R/CRTAM/CR1/KLRB1/CCR2/IL4I1/CD96/XCL1/RASGRP1/CLNK/IL1B/KLRC1/CR2/STAP1/LEP/AZGP1 |
23 |
| BP |
GO:0032944 |
regulation of mononuclear cell proliferation |
23/364 |
243/18903 |
3.64E-10 |
2.03E-08 |
1.63E-08 |
CD80/FCGR3A/IL10/IL6/IL2RA/SLAMF1/CRTAM/PLA2G2D/CTLA4/CR1/CD38/IDO1/CCR2/MZB1/IL4I1/CD274/XCL1/IKZF3/FCRL3/IL1B/CCL19/IGF2/LEP |
23 |
| BP |
GO:0070663 |
regulation of leukocyte proliferation |
24/364 |
269/18903 |
5.03E-10 |
2.77E-08 |
2.22E-08 |
CD80/FCGR3A/IL10/IL6/IL2RA/SLAMF1/CRTAM/PLA2G2D/CTLA4/CR1/CCL8/CD38/IDO1/CCR2/MZB1/IL4I1/CD274/XCL1/IKZF3/FCRL3/IL1B/CCL19/IGF2/LEP |
24 |
| BP |
GO:0002690 |
positive regulation of leukocyte chemotaxis |
15/364 |
97/18903 |
5.15E-10 |
2.79E-08 |
2.25E-08 |
CCL4/LBP/CCL3/CXCL13/IL6/SLAMF1/CCL7/CXCL10/PLA2G7/CCR2/XCL2/XCL1/CCR7/FPR2/CCL19 |
15 |
| BP |
GO:0002687 |
positive regulation of leukocyte migration |
18/364 |
148/18903 |
5.53E-10 |
2.96E-08 |
2.38E-08 |
CCL4/LBP/CCL3/CXCL13/IL6/SLAMF1/CCL7/CXCL10/ITGA4/CCL8/PLA2G7/CCR2/XCL2/XCL1/CCR7/FPR2/CCL19/CCL20 |
18 |
| BP |
GO:0002285 |
lymphocyte activation involved in immune response |
21/364 |
207/18903 |
6.06E-10 |
3.19E-08 |
2.57E-08 |
CD80/HLA-DRA/CD180/FCGR3A/BATF/IL10/IL6/SLAMF6/IFNG/CR1/CLEC4D/LY9/GAPT/IRF4/EOMES/IFNE/CLEC4E/POU2AF1/CCL19/CD19/PCK1 |
21 |
| BP |
GO:0050920 |
regulation of chemotaxis |
22/364 |
230/18903 |
7.25E-10 |
3.77E-08 |
3.03E-08 |
CCL4/LBP/SEMA3B/CCL3/SLAMF8/CXCL13/CXCR4/IL6/SLAMF1/CCL7/CXCL10/CCR4/PLA2G7/TNFAIP6/CCR2/XCL2/XCL1/CCR7/GPR18/STAP1/FPR2/CCL19 |
22 |
| BP |
GO:0016064 |
immunoglobulin mediated immune response |
21/364 |
215/18903 |
1.22E-09 |
6.24E-08 |
5.02E-08 |
FCGR1A/HLA-DQA1/HLA-DRA/IL21R/FCGR3A/BATF/IL10/CR1/TLR8/HLA-DOB/IGHG1/XCL1/IGLL5/GAPT/CR2/CD27/HLA-DQB2/IGHE/CD19/C6/IGHD |
21 |
| BP |
GO:0002274 |
myeloid leukocyte activation |
22/364 |
237/18903 |
1.28E-09 |
6.49E-08 |
5.22E-08 |
CXCL6/LBP/CCL3/FCGR3A/BATF/IL10/IL6/MAPT/UBD/CD300LF/SLAMF1/CD2/IFNG/CLEC4D/CCR2/RASGRP1/RHOH/CLNK/IRF4/STAP1/MT1G/CNR2 |
22 |
| BP |
GO:0042100 |
B cell proliferation |
15/364 |
104/18903 |
1.41E-09 |
7.03E-08 |
5.65E-08 |
CD180/IL10/IL7R/CTLA4/CD38/MZB1/RASGRP1/IKZF3/FCRL3/CD79A/GAPT/CR2/MS4A1/IFNE/CD19 |
15 |
| BP |
GO:0019724 |
B cell mediated immunity |
21/364 |
218/18903 |
1.57E-09 |
7.72E-08 |
6.21E-08 |
FCGR1A/HLA-DQA1/HLA-DRA/IL21R/FCGR3A/BATF/IL10/CR1/TLR8/HLA-DOB/IGHG1/XCL1/IGLL5/GAPT/CR2/CD27/HLA-DQB2/IGHE/CD19/C6/IGHD |
21 |
| BP |
GO:0002831 |
regulation of response to biotic stimulus |
27/364 |
361/18903 |
2.07E-09 |
1.01E-07 |
8.10E-08 |
CXCL6/LBP/CD180/SLAMF8/AIM2/SLAMF6/CRTAM/CR1/TLR8/BIRC3/KLRB1/GBP5/IL4I1/CD274/CD96/RASGRP1/MMP12/CLNK/IL1B/ZBP1/KLRC1/CLEC6A/PYHIN1/FCN1/FPR2/MIAT/LEP |
27 |
| BP |
GO:0071222 |
cellular response to lipopolysaccharide |
21/364 |
222/18903 |
2.18E-09 |
1.05E-07 |
8.43E-08 |
CXCL6/KMO/LBP/CXCL1/CD80/CCL3/CD180/CCR5/CXCL13/CXCL3/IL10/IL6/TNIP3/CXCL10/CXCL2/NUGGC/CXCL11/CXCL9/CD274/IL1B/STAP1 |
21 |
| BP |
GO:0002822 |
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains |
19/364 |
182/18903 |
2.50E-09 |
1.19E-07 |
9.54E-08 |
FCGR1A/CD80/HLA-DRA/BATF/IL10/IL6/SLAMF1/IL7R/CR1/CCR2/IL4I1/CD274/XCL1/IL1B/KLRC1/CLEC6A/CR2/CCL19/AZGP1 |
19 |
| BP |
GO:0050921 |
positive regulation of chemotaxis |
17/364 |
144/18903 |
2.66E-09 |
1.25E-07 |
1.01E-07 |
CCL4/LBP/CCL3/CXCL13/CXCR4/IL6/SLAMF1/CCL7/CXCL10/CCR4/PLA2G7/CCR2/XCL2/XCL1/CCR7/FPR2/CCL19 |
17 |
| BP |
GO:0002292 |
T cell differentiation involved in immune response |
13/364 |
79/18903 |
3.39E-09 |
1.57E-07 |
1.27E-07 |
CD80/HLA-DRA/BATF/IL6/SLAMF6/IFNG/CLEC4D/LY9/IRF4/EOMES/CLEC4E/CCL19/PCK1 |
13 |
| BP |
GO:0071347 |
cellular response to interleukin-1 |
15/364 |
111/18903 |
3.55E-09 |
1.62E-07 |
1.31E-07 |
CCL4/KMO/CCL18/CCL3/IL6/CCL7/CCL8/XCL2/XCL1/IL1B/ZBP1/CCL13/CCL19/IL1RN/CCL20 |
15 |
| BP |
GO:0050851 |
antigen receptor-mediated signaling pathway |
22/364 |
252/18903 |
4.04E-09 |
1.83E-07 |
1.47E-07 |
CTLA4/CD38/CD3D/TRAT1/GCSAM/IGHG1/LAX1/ITK/IGLL5/FCRL3/THEMIS/CD79A/CCR7/CD3G/MS4A1/STAP1/LCK/TRAC/TRGC2/IGHE/CD19/IGHD |
22 |
| BP |
GO:0034612 |
response to tumor necrosis factor |
22/364 |
254/18903 |
4.68E-09 |
2.09E-07 |
1.68E-07 |
CCL4/CCL18/CCL3/AIM2/SELE/UBD/CHI3L1/CCL7/CCL8/BIRC3/NLRP2/XCL2/XCL1/TNFRSF17/SLC2A4/CCL13/CCL19/CCL20/GPD1/TCL1A/FABP4/ADIPOQ |
22 |
| BP |
GO:2000403 |
positive regulation of lymphocyte migration |
10/364 |
42/18903 |
5.27E-09 |
2.33E-07 |
1.88E-07 |
CCL4/CCL3/CXCL13/CCL7/CXCL10/ITGA4/CCR2/XCL2/XCL1/CCL20 |
10 |
| BP |
GO:0071219 |
cellular response to molecule of bacterial origin |
21/364 |
234/18903 |
5.61E-09 |
2.46E-07 |
1.97E-07 |
CXCL6/KMO/LBP/CXCL1/CD80/CCL3/CD180/CCR5/CXCL13/CXCL3/IL10/IL6/TNIP3/CXCL10/CXCL2/NUGGC/CXCL11/CXCL9/CD274/IL1B/STAP1 |
21 |
| BP |
GO:0030183 |
B cell differentiation |
17/364 |
152/18903 |
6.13E-09 |
2.65E-07 |
2.13E-07 |
SLAMF8/IL10/IL6/ITGA4/CR1/IL2RG/IL4I1/IKZF3/FCRL3/CD79A/CR2/MS4A1/IFNE/CD27/POU2AF1/CD19/PAX5 |
17 |
| BP |
GO:2000401 |
regulation of lymphocyte migration |
12/364 |
69/18903 |
7.13E-09 |
3.05E-07 |
2.45E-07 |
CCL4/CCL3/CXCL13/CCL7/CXCL10/ITGA4/CCR2/GCSAM/XCL2/XCL1/APOD/CCL20 |
12 |
| BP |
GO:0046632 |
alpha-beta T cell differentiation |
15/364 |
117/18903 |
7.42E-09 |
3.14E-07 |
2.52E-07 |
CD80/HLA-DRA/ZBTB16/BATF/IL6/SLAMF6/PLA2G2D/IFNG/IL2RG/LY9/ITK/IRF4/GPR18/EOMES/CCL19 |
15 |
| BP |
GO:0002699 |
positive regulation of immune effector process |
22/364 |
261/18903 |
7.72E-09 |
3.23E-07 |
2.60E-07 |
FCGR1A/LBP/CD80/HLA-DRA/IL10/IL6/SLAMF6/SLAMF1/CRTAM/IFNG/CR1/CCR2/MZB1/XCL1/RASGRP1/CLNK/IL1B/STAP1/FCN1/CCL19/AZGP1/PCK1 |
22 |
| BP |
GO:0045088 |
regulation of innate immune response |
21/364 |
240/18903 |
8.81E-09 |
3.65E-07 |
2.93E-07 |
LBP/SLAMF8/AIM2/SLAMF6/CRTAM/CR1/TLR8/BIRC3/KLRB1/GBP5/CD96/RASGRP1/MMP12/CLNK/ZBP1/KLRC1/CLEC6A/PYHIN1/FCN1/FPR2/LEP |
21 |
| BP |
GO:0042129 |
regulation of T cell proliferation |
18/364 |
182/18903 |
1.55E-08 |
6.36E-07 |
5.11E-07 |
CD80/IL10/IL6/IL2RA/SLAMF1/CRTAM/PLA2G2D/CTLA4/CR1/IDO1/CCR2/IL4I1/CD274/XCL1/IL1B/CCL19/IGF2/LEP |
18 |
| BP |
GO:0072503 |
cellular divalent inorganic cation homeostasis |
24/364 |
323/18903 |
1.89E-08 |
7.66E-07 |
6.16E-07 |
SLC39A8/CCL3/CCR5/CCL7/CXCL10/CCL8/ATP1A2/TGM2/S100A9/CCR2/CXCL11/CXCL9/XCL1/GRIA1/FASLG/CCR7/CCL13/S100A8/LCK/CCL19/MT1G/CD19/JPH2/MT1H |
24 |
| BP |
GO:0002228 |
natural killer cell mediated immunity |
12/364 |
77/18903 |
2.59E-08 |
1.04E-06 |
8.35E-07 |
FCGR3A/SLAMF6/SLAMF7/CRTAM/CD2/KLRB1/CD96/RASGRP1/GZMB/CLNK/KLRC1/LEP |
12 |
| BP |
GO:1901623 |
regulation of lymphocyte chemotaxis |
8/364 |
27/18903 |
2.82E-08 |
1.12E-06 |
9.01E-07 |
CCL4/CCL3/CXCL13/CCL7/CXCL10/CCR2/XCL2/XCL1 |
8 |
| BP |
GO:0071356 |
cellular response to tumor necrosis factor |
20/364 |
234/18903 |
2.97E-08 |
1.17E-06 |
9.38E-07 |
CCL4/CCL18/CCL3/AIM2/CHI3L1/CCL7/CCL8/BIRC3/NLRP2/XCL2/XCL1/TNFRSF17/SLC2A4/CCL13/CCL19/CCL20/GPD1/TCL1A/FABP4/ADIPOQ |
20 |
| BP |
GO:0042098 |
T cell proliferation |
19/364 |
212/18903 |
3.09E-08 |
1.20E-06 |
9.66E-07 |
CD80/IL10/IL6/IL2RA/SLAMF1/CRTAM/PLA2G2D/CTLA4/CR1/IDO1/CCR2/IL4I1/CD274/XCL1/RASGRP1/IL1B/CCL19/IGF2/LEP |
19 |
| BP |
GO:0045621 |
positive regulation of lymphocyte differentiation |
15/364 |
130/18903 |
3.17E-08 |
1.22E-06 |
9.80E-07 |
CD80/HLA-DRA/ZBTB16/IL10/IL2RA/IL7R/IFNG/CR1/IL2RG/IL4I1/RASGRP1/RHOH/CD27/CCL19/PCK1 |
15 |
| BP |
GO:1903706 |
regulation of hemopoiesis |
27/364 |
413/18903 |
3.58E-08 |
1.36E-06 |
1.10E-06 |
CD80/HLA-DRA/CCL3/SLAMF8/ZBTB16/BATF/IL10/IL2RA/IL7R/CRTAM/CTLA4/CD2/IFNG/CR1/IL2RG/TNFAIP6/CCR2/IL4I1/RASGRP1/IKZF3/RHOH/FCRL3/IRF4/CD27/CCL19/ADIPOQ/PCK1 |
27 |
| BP |
GO:0071216 |
cellular response to biotic stimulus |
21/364 |
261/18903 |
3.82E-08 |
1.44E-06 |
1.16E-06 |
CXCL6/KMO/LBP/CXCL1/CD80/CCL3/CD180/CCR5/CXCL13/CXCL3/IL10/IL6/TNIP3/CXCL10/CXCL2/NUGGC/CXCL11/CXCL9/CD274/IL1B/STAP1 |
21 |
| BP |
GO:0035710 |
CD4-positive, alpha-beta T cell activation |
14/364 |
115/18903 |
4.61E-08 |
1.72E-06 |
1.39E-06 |
CD80/HLA-DRA/BATF/IL6/SLAMF6/IL2RA/PLA2G2D/IFNG/IL2RG/CD274/XCL1/LY9/IRF4/CCL19 |
14 |
| BP |
GO:0051235 |
maintenance of location |
24/364 |
342/18903 |
5.61E-08 |
2.08E-06 |
1.67E-06 |
SRGN/CCL3/CCR5/IL10/IL6/CXCL10/ATP1A2/ASPM/S100A9/CXCL11/CXCL9/XCL1/FASLG/IL1B/CCR7/S100A8/GRIK5/LCK/CCL19/CD19/JPH2/PLIN5/CIDEA/LEP |
24 |
| BP |
GO:0002695 |
negative regulation of leukocyte activation |
18/364 |
198/18903 |
5.75E-08 |
2.09E-06 |
1.68E-06 |
SAMSN1/CD80/IL10/CD300LF/IL2RA/CRTAM/PLA2G2D/CTLA4/CR1/TIGIT/IDO1/CCR2/IL4I1/LAX1/CD274/XCL1/CLNK/CNR2 |
18 |
| BP |
GO:0045582 |
positive regulation of T cell differentiation |
14/364 |
117/18903 |
5.75E-08 |
2.09E-06 |
1.68E-06 |
CD80/HLA-DRA/ZBTB16/IL2RA/IL7R/IFNG/CR1/IL2RG/IL4I1/RASGRP1/RHOH/CD27/CCL19/PCK1 |
14 |
| BP |
GO:0002286 |
T cell activation involved in immune response |
14/364 |
118/18903 |
6.41E-08 |
2.31E-06 |
1.86E-06 |
CD80/HLA-DRA/BATF/IL6/SLAMF6/IFNG/CLEC4D/LY9/IRF4/EOMES/IFNE/CLEC4E/CCL19/PCK1 |
14 |
| BP |
GO:0032609 |
interferon-gamma production |
14/364 |
119/18903 |
7.14E-08 |
2.52E-06 |
2.03E-06 |
IL10/SLAMF6/SLAMF1/CRTAM/CD2/CR1/TLR8/CCR2/CD274/CD96/XCL1/RASGRP1/IL1B/CCR7 |
14 |
| BP |
GO:0032649 |
regulation of interferon-gamma production |
14/364 |
119/18903 |
7.14E-08 |
2.52E-06 |
2.03E-06 |
IL10/SLAMF6/SLAMF1/CRTAM/CD2/CR1/TLR8/CCR2/CD274/CD96/XCL1/RASGRP1/IL1B/CCR7 |
14 |
| BP |
GO:0031341 |
regulation of cell killing |
13/364 |
102/18903 |
8.07E-08 |
2.82E-06 |
2.27E-06 |
CXCL6/HLA-DRA/SLAMF6/IL7R/CRTAM/IFNG/KLRB1/XCL1/RASGRP1/KLRC1/STAP1/LEP/AZGP1 |
13 |
| BP |
GO:0140131 |
positive regulation of lymphocyte chemotaxis |
7/364 |
21/18903 |
8.54E-08 |
2.96E-06 |
2.38E-06 |
CCL4/CCL3/CXCL13/CCL7/CCR2/XCL2/XCL1 |
7 |
| BP |
GO:0034341 |
response to interferon-gamma |
15/364 |
140/18903 |
8.60E-08 |
2.96E-06 |
2.38E-06 |
CCL4/KYNU/CCL18/CCL3/UBD/CCL7/IFNG/CCL8/GBP5/XCL2/XCL1/FASLG/CCL13/CCL19/CCL20 |
15 |
| BP |
GO:0050864 |
regulation of B cell activation |
18/364 |
204/18903 |
9.08E-08 |
3.07E-06 |
2.47E-06 |
SAMSN1/SLAMF8/IL10/IL6/CTLA4/CR1/CD38/IL2RG/MZB1/IGHG1/IL4I1/IKZF3/IGLL5/FCRL3/CD27/IGHE/CD19/IGHD |
18 |
| BP |
GO:0042130 |
negative regulation of T cell proliferation |
11/364 |
70/18903 |
9.10E-08 |
3.07E-06 |
2.47E-06 |
CD80/IL10/IL2RA/CRTAM/PLA2G2D/CTLA4/CR1/IDO1/IL4I1/CD274/XCL1 |
11 |
| BP |
GO:0007204 |
positive regulation of cytosolic calcium ion concentration |
18/364 |
205/18903 |
9.78E-08 |
3.27E-06 |
2.63E-06 |
GPR65/CCR5/CXCL13/CXCR4/FPR1/CCR4/CD38/CXCR6/P2RY10/CCR2/CD52/ADCY5/GPR174/CCR7/GPR18/FPR2/ADRA1A/JPH2 |
18 |
| BP |
GO:0001910 |
regulation of leukocyte mediated cytotoxicity |
12/364 |
87/18903 |
1.05E-07 |
3.49E-06 |
2.81E-06 |
CXCL6/HLA-DRA/SLAMF6/IL7R/CRTAM/KLRB1/XCL1/RASGRP1/KLRC1/STAP1/LEP/AZGP1 |
12 |
| BP |
GO:0072507 |
divalent inorganic cation homeostasis |
24/364 |
356/18903 |
1.19E-07 |
3.91E-06 |
3.15E-06 |
SLC39A8/CCL3/CCR5/CCL7/CXCL10/CCL8/ATP1A2/TGM2/S100A9/CCR2/CXCL11/CXCL9/XCL1/GRIA1/FASLG/CCR7/CCL13/S100A8/LCK/CCL19/MT1G/CD19/JPH2/MT1H |
24 |
| BP |
GO:0002833 |
positive regulation of response to biotic stimulus |
17/364 |
188/18903 |
1.46E-07 |
4.75E-06 |
3.82E-06 |
LBP/CD180/AIM2/SLAMF6/CRTAM/TLR8/GBP5/CD274/RASGRP1/MMP12/CLNK/ZBP1/CLEC6A/PYHIN1/FCN1/FPR2/MIAT |
17 |
| BP |
GO:0071706 |
tumor necrosis factor superfamily cytokine production |
17/364 |
189/18903 |
1.57E-07 |
5.04E-06 |
4.06E-06 |
LBP/CCL3/FCGR3A/IL10/IL6/SLAMF1/CD2/IFNG/CCR2/CD274/RASGRP1/GPR18/LILRA4/CCL19/CIDEA/LEP/ADIPOQ |
17 |
| BP |
GO:1903555 |
regulation of tumor necrosis factor superfamily cytokine production |
17/364 |
189/18903 |
1.57E-07 |
5.04E-06 |
4.06E-06 |
LBP/CCL3/FCGR3A/IL10/IL6/SLAMF1/CD2/IFNG/CCR2/CD274/RASGRP1/GPR18/LILRA4/CCL19/CIDEA/LEP/ADIPOQ |
17 |
| BP |
GO:0045577 |
regulation of B cell differentiation |
8/364 |
33/18903 |
1.60E-07 |
5.08E-06 |
4.08E-06 |
SLAMF8/IL10/CR1/IL2RG/IL4I1/IKZF3/FCRL3/CD27 |
8 |
| BP |
GO:0050853 |
B cell receptor signaling pathway |
14/364 |
130/18903 |
2.18E-07 |
6.88E-06 |
5.54E-06 |
CTLA4/CD38/GCSAM/IGHG1/ITK/IGLL5/FCRL3/CD79A/MS4A1/STAP1/LCK/IGHE/CD19/IGHD |
14 |
| BP |
GO:0050866 |
negative regulation of cell activation |
18/364 |
221/18903 |
3.03E-07 |
9.48E-06 |
7.62E-06 |
SAMSN1/CD80/IL10/CD300LF/IL2RA/CRTAM/PLA2G2D/CTLA4/CR1/TIGIT/IDO1/CCR2/IL4I1/LAX1/CD274/XCL1/CLNK/CNR2 |
18 |
| BP |
GO:0070664 |
negative regulation of leukocyte proliferation |
12/364 |
96/18903 |
3.17E-07 |
9.84E-06 |
7.92E-06 |
CD80/IL10/IL2RA/CRTAM/PLA2G2D/CTLA4/CR1/CCL8/IDO1/IL4I1/CD274/XCL1 |
12 |
| BP |
GO:0046634 |
regulation of alpha-beta T cell activation |
13/364 |
115/18903 |
3.36E-07 |
1.04E-05 |
8.33E-06 |
CD80/HLA-DRA/ZBTB16/BATF/IL2RA/CRTAM/IFNG/IL2RG/CCR2/CD274/XCL1/IRF4/CCL19 |
13 |
| BP |
GO:0071887 |
leukocyte apoptotic process |
13/364 |
117/18903 |
4.12E-07 |
1.26E-05 |
1.01E-05 |
IL10/IL6/IL2RA/IL7R/IDO1/CD274/FASLG/CCR7/CD3G/CD27/CCL19/PDCD1/MIAT |
13 |
| BP |
GO:0051651 |
maintenance of location in cell |
18/364 |
226/18903 |
4.22E-07 |
1.28E-05 |
1.03E-05 |
SRGN/CCL3/CCR5/CXCL10/ATP1A2/ASPM/S100A9/CXCL11/CXCL9/XCL1/FASLG/CCR7/S100A8/GRIK5/LCK/CCL19/CD19/JPH2 |
18 |
| BP |
GO:0042742 |
defense response to bacterium |
24/364 |
382/18903 |
4.32E-07 |
1.30E-05 |
1.05E-05 |
CXCL6/FCGR1A/LBP/SLAMF8/CXCL13/IL10/IL6/LYZ/IL7R/S100A9/CLEC4D/IGHG1/IGLL5/IL1B/S100A8/PLAC8/IFNE/CLEC4E/FPR2/IGHE/GSDMC/CCL20/MIAT/IGHD |
24 |
| BP |
GO:0071346 |
cellular response to interferon-gamma |
13/364 |
118/18903 |
4.55E-07 |
1.36E-05 |
1.09E-05 |
CCL4/CCL18/CCL3/CCL7/IFNG/CCL8/GBP5/XCL2/XCL1/FASLG/CCL13/CCL19/CCL20 |
13 |
| BP |
GO:0045058 |
T cell selection |
9/364 |
51/18903 |
4.92E-07 |
1.46E-05 |
1.17E-05 |
BATF/IL6/SLAMF6/CD3D/LY9/THEMIS/IRF4/CCR7/CD3G |
9 |
| BP |
GO:0043368 |
positive T cell selection |
8/364 |
38/18903 |
5.17E-07 |
1.52E-05 |
1.22E-05 |
BATF/IL6/SLAMF6/CD3D/LY9/THEMIS/IRF4/CD3G |
8 |
| BP |
GO:0032640 |
tumor necrosis factor production |
16/364 |
184/18903 |
5.77E-07 |
1.67E-05 |
1.34E-05 |
LBP/CCL3/FCGR3A/IL10/IL6/SLAMF1/CD2/IFNG/CCR2/RASGRP1/GPR18/LILRA4/CCL19/CIDEA/LEP/ADIPOQ |
16 |
| BP |
GO:0032680 |
regulation of tumor necrosis factor production |
16/364 |
184/18903 |
5.77E-07 |
1.67E-05 |
1.34E-05 |
LBP/CCL3/FCGR3A/IL10/IL6/SLAMF1/CD2/IFNG/CCR2/RASGRP1/GPR18/LILRA4/CCL19/CIDEA/LEP/ADIPOQ |
16 |
| BP |
GO:0002407 |
dendritic cell chemotaxis |
7/364 |
27/18903 |
5.91E-07 |
1.70E-05 |
1.36E-05 |
SLAMF8/CCR5/CXCR4/SLAMF1/CCR2/CCR7/CCL19 |
7 |
| BP |
GO:0006875 |
cellular metal ion homeostasis |
25/364 |
420/18903 |
6.76E-07 |
1.93E-05 |
1.55E-05 |
SLC39A8/CCL3/CCR5/CCL7/CXCL10/IFNG/CCL8/ATP1A2/TGM2/S100A9/CCR2/CXCL11/CXCL9/XCL1/GRIA1/FASLG/CCR7/CCL13/S100A8/LCK/CCL19/MT1G/CD19/JPH2/MT1H |
25 |
| BP |
GO:0010818 |
T cell chemotaxis |
7/364 |
28/18903 |
7.74E-07 |
2.19E-05 |
1.76E-05 |
CCL3/CXCL13/CXCL10/CCR2/CXCL11/XCL2/XCL1 |
7 |
| BP |
GO:0051250 |
negative regulation of lymphocyte activation |
15/364 |
166/18903 |
7.99E-07 |
2.24E-05 |
1.81E-05 |
SAMSN1/CD80/IL10/IL2RA/CRTAM/PLA2G2D/CTLA4/CR1/TIGIT/IDO1/IL4I1/LAX1/CD274/XCL1/CLNK |
15 |
| BP |
GO:0051209 |
release of sequestered calcium ion into cytosol |
13/364 |
124/18903 |
8.08E-07 |
2.26E-05 |
1.81E-05 |
CCL3/CCR5/CXCL10/ATP1A2/CXCL11/CXCL9/XCL1/FASLG/CCR7/LCK/CCL19/CD19/JPH2 |
13 |
| BP |
GO:0045089 |
positive regulation of innate immune response |
14/364 |
145/18903 |
8.38E-07 |
2.32E-05 |
1.87E-05 |
LBP/AIM2/SLAMF6/CRTAM/TLR8/GBP5/RASGRP1/MMP12/CLNK/ZBP1/CLEC6A/PYHIN1/FCN1/FPR2 |
14 |
| BP |
GO:0050672 |
negative regulation of lymphocyte proliferation |
11/364 |
87/18903 |
8.79E-07 |
2.42E-05 |
1.94E-05 |
CD80/IL10/IL2RA/CRTAM/PLA2G2D/CTLA4/CR1/IDO1/IL4I1/CD274/XCL1 |
11 |
| BP |
GO:0051283 |
negative regulation of sequestering of calcium ion |
13/364 |
125/18903 |
8.87E-07 |
2.42E-05 |
1.95E-05 |
CCL3/CCR5/CXCL10/ATP1A2/CXCL11/CXCL9/XCL1/FASLG/CCR7/LCK/CCL19/CD19/JPH2 |
13 |
| BP |
GO:0050671 |
positive regulation of lymphocyte proliferation |
14/364 |
146/18903 |
9.11E-07 |
2.47E-05 |
1.99E-05 |
CD80/FCGR3A/IL6/IL2RA/SLAMF1/CD38/CCR2/CD274/XCL1/FCRL3/IL1B/CCL19/IGF2/LEP |
14 |
| BP |
GO:0032945 |
negative regulation of mononuclear cell proliferation |
11/364 |
88/18903 |
9.88E-07 |
2.64E-05 |
2.12E-05 |
CD80/IL10/IL2RA/CRTAM/PLA2G2D/CTLA4/CR1/IDO1/IL4I1/CD274/XCL1 |
11 |
| BP |
GO:0043367 |
CD4-positive, alpha-beta T cell differentiation |
11/364 |
88/18903 |
9.88E-07 |
2.64E-05 |
2.12E-05 |
CD80/HLA-DRA/BATF/IL6/SLAMF6/PLA2G2D/IFNG/IL2RG/LY9/IRF4/CCL19 |
11 |
| BP |
GO:0001773 |
myeloid dendritic cell activation |
7/364 |
29/18903 |
1.00E-06 |
2.64E-05 |
2.12E-05 |
BATF/IL10/UBD/SLAMF1/CD2/CLEC4D/IRF4 |
7 |
| BP |
GO:0002287 |
alpha-beta T cell activation involved in immune response |
10/364 |
71/18903 |
1.01E-06 |
2.64E-05 |
2.12E-05 |
CD80/HLA-DRA/BATF/IL6/SLAMF6/IFNG/LY9/IRF4/EOMES/CCL19 |
10 |
| BP |
GO:0002293 |
alpha-beta T cell differentiation involved in immune response |
10/364 |
71/18903 |
1.01E-06 |
2.64E-05 |
2.12E-05 |
CD80/HLA-DRA/BATF/IL6/SLAMF6/IFNG/LY9/IRF4/EOMES/CCL19 |
10 |
| BP |
GO:0051282 |
regulation of sequestering of calcium ion |
13/364 |
127/18903 |
1.06E-06 |
2.77E-05 |
2.23E-05 |
CCL3/CCR5/CXCL10/ATP1A2/CXCL11/CXCL9/XCL1/FASLG/CCR7/LCK/CCL19/CD19/JPH2 |
13 |
| BP |
GO:0002523 |
leukocyte migration involved in inflammatory response |
6/364 |
19/18903 |
1.07E-06 |
2.78E-05 |
2.23E-05 |
LBP/SLAMF8/SELE/SLAMF1/S100A9/S100A8 |
6 |
| BP |
GO:0006568 |
tryptophan metabolic process |
5/364 |
11/18903 |
1.08E-06 |
2.78E-05 |
2.23E-05 |
KMO/KYNU/IDO1/TDO2/IL4I1 |
5 |
| BP |
GO:0050868 |
negative regulation of T cell activation |
13/364 |
128/18903 |
1.16E-06 |
2.95E-05 |
2.37E-05 |
CD80/IL10/IL2RA/CRTAM/PLA2G2D/CTLA4/CR1/TIGIT/IDO1/IL4I1/LAX1/CD274/XCL1 |
13 |
| BP |
GO:0032946 |
positive regulation of mononuclear cell proliferation |
14/364 |
149/18903 |
1.17E-06 |
2.95E-05 |
2.37E-05 |
CD80/FCGR3A/IL6/IL2RA/SLAMF1/CD38/CCR2/CD274/XCL1/FCRL3/IL1B/CCL19/IGF2/LEP |
14 |
| BP |
GO:0072678 |
T cell migration |
10/364 |
73/18903 |
1.31E-06 |
3.30E-05 |
2.65E-05 |
CCL3/CXCL13/CXCL10/ITGA4/CCR2/CXCL11/XCL2/XCL1/APOD/CCL20 |
10 |
| BP |
GO:0032732 |
positive regulation of interleukin-1 production |
10/364 |
74/18903 |
1.49E-06 |
3.70E-05 |
2.97E-05 |
CCL3/AIM2/IL6/IFNG/TLR8/GBP5/NLRP2/PYHIN1/CCL19/IGHD |
10 |
| BP |
GO:0042267 |
natural killer cell mediated cytotoxicity |
10/364 |
74/18903 |
1.49E-06 |
3.70E-05 |
2.97E-05 |
FCGR3A/SLAMF6/SLAMF7/CRTAM/CD2/KLRB1/RASGRP1/GZMB/KLRC1/LEP |
10 |
| BP |
GO:0051208 |
sequestering of calcium ion |
13/364 |
131/18903 |
1.52E-06 |
3.74E-05 |
3.01E-05 |
CCL3/CCR5/CXCL10/ATP1A2/CXCL11/CXCL9/XCL1/FASLG/CCR7/LCK/CCL19/CD19/JPH2 |
13 |
| BP |
GO:0002456 |
T cell mediated immunity |
12/364 |
113/18903 |
1.87E-06 |
4.59E-05 |
3.69E-05 |
HLA-DRA/IL6/SLAMF1/IL7R/CCR2/IL4I1/XCL1/TRA/IL1B/KLRC1/AZGP1/KDM5D |
12 |
| BP |
GO:0097553 |
calcium ion transmembrane import into cytosol |
15/364 |
182/18903 |
2.55E-06 |
6.22E-05 |
5.00E-05 |
CCL3/CCR5/CXCL10/ATP1A2/CXCL11/CXCL9/XCL1/FASLG/CCR7/MS4A1/LCK/CCL19/CD19/ADRA1A/JPH2 |
15 |
| BP |
GO:2000514 |
regulation of CD4-positive, alpha-beta T cell activation |
10/364 |
79/18903 |
2.74E-06 |
6.64E-05 |
5.34E-05 |
CD80/HLA-DRA/BATF/IL2RA/IFNG/IL2RG/CD274/XCL1/IRF4/CCL19 |
10 |
| BP |
GO:0006874 |
cellular calcium ion homeostasis |
19/364 |
284/18903 |
2.81E-06 |
6.77E-05 |
5.44E-05 |
CCL3/CCR5/CCL7/CXCL10/CCL8/ATP1A2/TGM2/CCR2/CXCL11/CXCL9/XCL1/GRIA1/FASLG/CCR7/CCL13/LCK/CCL19/CD19/JPH2 |
19 |
| BP |
GO:0006586 |
indolalkylamine metabolic process |
5/364 |
13/18903 |
2.92E-06 |
6.87E-05 |
5.52E-05 |
KMO/KYNU/IDO1/TDO2/IL4I1 |
5 |
| BP |
GO:1902107 |
positive regulation of leukocyte differentiation |
15/364 |
184/18903 |
2.92E-06 |
6.87E-05 |
5.52E-05 |
CD80/HLA-DRA/ZBTB16/IL10/IL2RA/IL7R/IFNG/CR1/IL2RG/IL4I1/RASGRP1/RHOH/CD27/CCL19/PCK1 |
15 |
| BP |
GO:1903708 |
positive regulation of hemopoiesis |
15/364 |
184/18903 |
2.92E-06 |
6.87E-05 |
5.52E-05 |
CD80/HLA-DRA/ZBTB16/IL10/IL2RA/IL7R/IFNG/CR1/IL2RG/IL4I1/RASGRP1/RHOH/CD27/CCL19/PCK1 |
15 |
| BP |
GO:0019722 |
calcium-mediated signaling |
16/364 |
208/18903 |
2.92E-06 |
6.87E-05 |
5.52E-05 |
CCL4/CCL3/CCR5/FCGR3A/CXCR4/MAPT/SELE/CCR4/ATP1A2/CXCR6/TRAT1/CCR2/CCR7/FPR2/BHLHA15/CCL20 |
16 |
| BP |
GO:0032615 |
interleukin-12 production |
9/364 |
63/18903 |
3.12E-06 |
7.15E-05 |
5.75E-05 |
IL10/SLAMF1/IFNG/TLR8/TIGIT/IDO1/CCR7/CCL19/LEP |
9 |
| BP |
GO:0032655 |
regulation of interleukin-12 production |
9/364 |
63/18903 |
3.12E-06 |
7.15E-05 |
5.75E-05 |
IL10/SLAMF1/IFNG/TLR8/TIGIT/IDO1/CCR7/CCL19/LEP |
9 |
| BP |
GO:0032731 |
positive regulation of interleukin-1 beta production |
9/364 |
63/18903 |
3.12E-06 |
7.15E-05 |
5.75E-05 |
CCL3/AIM2/IL6/IFNG/TLR8/GBP5/NLRP2/PYHIN1/CCL19 |
9 |
| BP |
GO:0032757 |
positive regulation of interleukin-8 production |
9/364 |
63/18903 |
3.12E-06 |
7.15E-05 |
5.75E-05 |
LBP/IL6/CHI3L1/CD2/TLR8/IL1B/FCN1/LEP/ADIPOQ |
9 |
| BP |
GO:0036336 |
dendritic cell migration |
7/364 |
34/18903 |
3.19E-06 |
7.26E-05 |
5.83E-05 |
SLAMF8/CCR5/CXCR4/SLAMF1/CCR2/CCR7/CCL19 |
7 |
| BP |
GO:0061844 |
antimicrobial humoral immune response mediated by antimicrobial peptide |
10/364 |
81/18903 |
3.46E-06 |
7.83E-05 |
6.29E-05 |
CXCL6/CXCL1/CXCL13/CXCL3/CXCL10/CXCL2/S100A9/CXCL11/CXCL9/CCL13 |
10 |
| BP |
GO:2000406 |
positive regulation of T cell migration |
7/364 |
35/18903 |
3.92E-06 |
8.82E-05 |
7.09E-05 |
CXCL13/CXCL10/ITGA4/CCR2/XCL2/XCL1/CCL20 |
7 |
| BP |
GO:2000404 |
regulation of T cell migration |
8/364 |
49/18903 |
3.96E-06 |
8.87E-05 |
7.13E-05 |
CXCL13/CXCL10/ITGA4/CCR2/XCL2/XCL1/APOD/CCL20 |
8 |
| BP |
GO:0002698 |
negative regulation of immune effector process |
12/364 |
122/18903 |
4.21E-06 |
9.37E-05 |
7.53E-05 |
SLAMF8/IL10/SLAMF1/IL7R/CR1/CCR2/IL4I1/CD96/XCL1/FCRL3/KLRC1/CR2 |
12 |
| BP |
GO:0050777 |
negative regulation of immune response |
15/364 |
190/18903 |
4.34E-06 |
9.61E-05 |
7.73E-05 |
SAMSN1/SLAMF8/IL10/SLAMF1/IL7R/CTLA4/CR1/CCR2/IL4I1/CD96/XCL1/MMP12/KLRC1/CR2/PDCD1 |
15 |
| BP |
GO:0072540 |
T-helper 17 cell lineage commitment |
5/364 |
14/18903 |
4.47E-06 |
9.83E-05 |
7.91E-05 |
BATF/IL6/SLAMF6/LY9/IRF4 |
5 |
| BP |
GO:0070665 |
positive regulation of leukocyte proliferation |
14/364 |
167/18903 |
4.52E-06 |
9.88E-05 |
7.94E-05 |
CD80/FCGR3A/IL6/IL2RA/SLAMF1/CD38/CCR2/CD274/XCL1/FCRL3/IL1B/CCL19/IGF2/LEP |
14 |
| BP |
GO:0030003 |
cellular cation homeostasis |
26/364 |
499/18903 |
4.74E-06 |
0.0001029 |
8.28E-05 |
SLC39A8/CCL3/SLAMF8/CCR5/CCL7/CXCL10/IFNG/CCL8/ATP1A2/TGM2/S100A9/CCR2/CXCL11/CXCL9/XCL1/GRIA1/FASLG/CCR7/CCL13/S100A8/LCK/CCL19/MT1G/CD19/JPH2/MT1H |
26 |
| BP |
GO:0050764 |
regulation of phagocytosis |
11/364 |
103/18903 |
4.76E-06 |
0.0001029 |
8.28E-05 |
FCGR1A/CD300LF/IFNG/IL2RG/TGM2/SIRPG/IL1B/STAP1/FCN1/FPR2/ADIPOQ |
11 |
| BP |
GO:0002715 |
regulation of natural killer cell mediated immunity |
8/364 |
51/18903 |
5.41E-06 |
0.0001164 |
9.36E-05 |
SLAMF6/CRTAM/KLRB1/CD96/RASGRP1/CLNK/KLRC1/LEP |
8 |
| BP |
GO:1903038 |
negative regulation of leukocyte cell-cell adhesion |
13/364 |
147/18903 |
5.51E-06 |
0.0001179 |
9.48E-05 |
CD80/IL10/IL2RA/CRTAM/PLA2G2D/CTLA4/CR1/TIGIT/IDO1/IL4I1/LAX1/CD274/XCL1 |
13 |
| BP |
GO:0002335 |
mature B cell differentiation |
7/364 |
37/18903 |
5.80E-06 |
0.0001234 |
9.92E-05 |
SLAMF8/IL10/IL6/CR1/IL2RG/POU2AF1/CD19 |
7 |
| BP |
GO:0002704 |
negative regulation of leukocyte mediated immunity |
9/364 |
68/18903 |
5.97E-06 |
0.0001263 |
0.0001016 |
SLAMF1/IL7R/CR1/CCR2/IL4I1/CD96/XCL1/KLRC1/CR2 |
9 |
| BP |
GO:0042102 |
positive regulation of T cell proliferation |
11/364 |
106/18903 |
6.30E-06 |
0.0001325 |
0.0001066 |
CD80/IL6/IL2RA/SLAMF1/CCR2/CD274/XCL1/IL1B/CCL19/IGF2/LEP |
11 |
| BP |
GO:0019835 |
cytolysis |
6/364 |
25/18903 |
6.36E-06 |
0.000133 |
0.000107 |
LBP/LYZ/CR1/GZMA/GZMB/C6 |
6 |
| BP |
GO:0070374 |
positive regulation of ERK1 and ERK2 cascade |
16/364 |
223/18903 |
7.15E-06 |
0.0001488 |
0.0001196 |
CCL4/CCL18/CCL3/CHI3L1/SLAMF1/CCL7/CCL8/XCL2/XCL1/RASGRP1/CCR7/CCL13/FPR2/CCL19/ADRA1A/CCL20 |
16 |
| BP |
GO:0002294 |
CD4-positive, alpha-beta T cell differentiation involved in immune response |
9/364 |
70/18903 |
7.62E-06 |
0.0001577 |
0.0001268 |
CD80/HLA-DRA/BATF/IL6/SLAMF6/IFNG/LY9/IRF4/CCL19 |
9 |
| BP |
GO:0032612 |
interleukin-1 production |
12/364 |
130/18903 |
8.14E-06 |
0.0001663 |
0.0001337 |
CCL3/AIM2/IL10/IL6/IFNG/TLR8/GBP5/NLRP2/CCR7/PYHIN1/CCL19/IGHD |
12 |
| BP |
GO:0032652 |
regulation of interleukin-1 production |
12/364 |
130/18903 |
8.14E-06 |
0.0001663 |
0.0001337 |
CCL3/AIM2/IL10/IL6/IFNG/TLR8/GBP5/NLRP2/CCR7/PYHIN1/CCL19/IGHD |
12 |
| BP |
GO:0002709 |
regulation of T cell mediated immunity |
10/364 |
89/18903 |
8.16E-06 |
0.0001663 |
0.0001337 |
HLA-DRA/IL6/SLAMF1/IL7R/CCR2/IL4I1/XCL1/IL1B/KLRC1/AZGP1 |
10 |
| BP |
GO:0045066 |
regulatory T cell differentiation |
7/364 |
39/18903 |
8.38E-06 |
0.0001699 |
0.0001366 |
HLA-DRA/PLA2G2D/CTLA4/IFNG/CR1/IL2RG/IL4I1 |
7 |
| BP |
GO:0007162 |
negative regulation of cell adhesion |
19/364 |
308/18903 |
9.07E-06 |
0.0001829 |
0.0001471 |
ADAMDEC1/CD80/MYOC/IL10/IL2RA/CRTAM/PLA2G2D/CTLA4/CR1/TIGIT/IDO1/IL4I1/LAX1/CD274/XCL1/MMP12/APOD/IL1RN/ADIPOQ |
19 |
| BP |
GO:0022408 |
negative regulation of cell-cell adhesion |
15/364 |
202/18903 |
9.14E-06 |
0.0001834 |
0.0001474 |
CD80/IL10/IL2RA/CRTAM/PLA2G2D/CTLA4/CR1/TIGIT/IDO1/IL4I1/LAX1/CD274/XCL1/IL1RN/ADIPOQ |
15 |
| BP |
GO:0009074 |
aromatic amino acid family catabolic process |
5/364 |
16/18903 |
9.45E-06 |
0.0001885 |
0.0001515 |
KMO/KYNU/IDO1/TDO2/IL4I1 |
5 |
| BP |
GO:0055074 |
calcium ion homeostasis |
19/364 |
309/18903 |
9.50E-06 |
0.0001885 |
0.0001516 |
CCL3/CCR5/CCL7/CXCL10/CCL8/ATP1A2/TGM2/CCR2/CXCL11/CXCL9/XCL1/GRIA1/FASLG/CCR7/CCL13/LCK/CCL19/CD19/JPH2 |
19 |
| BP |
GO:0042063 |
gliogenesis |
19/364 |
310/18903 |
9.95E-06 |
0.0001964 |
0.0001579 |
CCL3/MYOC/CXCR4/IL6/MAPT/LGI4/IFNG/S100A9/CCR2/CDK1/KLF15/IL1B/NTN1/S100A8/EOMES/STAP1/SOX10/CNTN2/KCNJ10 |
19 |
| BP |
GO:0043547 |
positive regulation of GTPase activity |
18/364 |
283/18903 |
1.03E-05 |
0.0002025 |
0.0001628 |
CCL4/CCL18/CCL3/GPR65/RGS6/CXCL13/WNT11/CCL7/CCL8/RGS1/TGM2/XCL2/XCL1/RASGRP1/CCR7/CCL13/CCL19/CCL20 |
18 |
| BP |
GO:0070371 |
ERK1 and ERK2 cascade |
20/364 |
340/18903 |
1.07E-05 |
0.0002083 |
0.0001675 |
CCL4/CCL18/CCL3/CHI3L1/SLAMF1/CCL7/CCL8/CDK1/XCL2/XCL1/RASGRP1/WNK2/IL1B/CCR7/CCL13/FPR2/CCL19/ADRA1A/CCL20/ADIPOQ |
20 |
| BP |
GO:0002707 |
negative regulation of lymphocyte mediated immunity |
8/364 |
56/18903 |
1.11E-05 |
0.0002159 |
0.0001736 |
SLAMF1/IL7R/CR1/IL4I1/CD96/XCL1/KLRC1/CR2 |
8 |
| BP |
GO:0006909 |
phagocytosis |
19/364 |
314/18903 |
1.19E-05 |
0.0002306 |
0.0001854 |
FCGR1A/LBP/CD300LF/SLAMF1/IFNG/IL2RG/TGM2/IGHG1/SIRPG/RHOH/IGLL5/IL1B/STAP1/FCN1/FPR2/IGHE/LEP/IGHD/ADIPOQ |
19 |
| BP |
GO:0050766 |
positive regulation of phagocytosis |
9/364 |
74/18903 |
1.21E-05 |
0.0002321 |
0.0001866 |
FCGR1A/CD300LF/IFNG/IL2RG/SIRPG/IL1B/STAP1/FCN1/FPR2 |
9 |
| BP |
GO:2000106 |
regulation of leukocyte apoptotic process |
10/364 |
93/18903 |
1.21E-05 |
0.0002321 |
0.0001866 |
IL10/IL7R/IDO1/CD274/CCR7/CD3G/CD27/CCL19/PDCD1/MIAT |
10 |
| BP |
GO:0070372 |
regulation of ERK1 and ERK2 cascade |
19/364 |
315/18903 |
1.25E-05 |
0.0002376 |
0.000191 |
CCL4/CCL18/CCL3/CHI3L1/SLAMF1/CCL7/CCL8/XCL2/XCL1/RASGRP1/WNK2/IL1B/CCR7/CCL13/FPR2/CCL19/ADRA1A/CCL20/ADIPOQ |
19 |
| BP |
GO:0043410 |
positive regulation of MAPK cascade |
25/364 |
496/18903 |
1.28E-05 |
0.0002422 |
0.0001947 |
CCL4/CCL18/CCL3/IL6/CHI3L1/SLAMF1/CCL7/OSM/CCL8/ADRA2B/XCL2/XCL1/RASGRP1/FCRL3/IL1B/CCR7/CCL13/CD27/FPR2/CCL19/IGF2/ADRA1A/CCL20/KLB/LEP |
25 |
| BP |
GO:0010819 |
regulation of T cell chemotaxis |
5/364 |
17/18903 |
1.32E-05 |
0.0002486 |
0.0001999 |
CXCL13/CXCL10/CCR2/XCL2/XCL1 |
5 |
| BP |
GO:0009615 |
response to virus |
22/364 |
409/18903 |
1.58E-05 |
0.0002972 |
0.0002389 |
CCL4/AIM2/CXCR4/IL6/CXCL10/IFNG/TLR8/CCL8/BIRC3/APOBEC3H/CXCL9/XCL1/MMP12/IL1B/ZBP1/RNASE2/PIM2/IFNE/POU2AF1/CCL19/DUOX2/APOBEC3A |
22 |
| BP |
GO:0021782 |
glial cell development |
11/364 |
117/18903 |
1.63E-05 |
0.0003044 |
0.0002448 |
MYOC/IL6/MAPT/LGI4/IFNG/S100A9/IL1B/S100A8/SOX10/CNTN2/KCNJ10 |
11 |
| BP |
GO:0002705 |
positive regulation of leukocyte mediated immunity |
12/364 |
140/18903 |
1.73E-05 |
0.0003225 |
0.0002593 |
FCGR1A/HLA-DRA/IL6/SLAMF6/SLAMF1/CRTAM/XCL1/RASGRP1/CLNK/IL1B/STAP1/AZGP1 |
12 |
| BP |
GO:0002295 |
T-helper cell lineage commitment |
5/364 |
18/18903 |
1.80E-05 |
0.0003323 |
0.0002672 |
BATF/IL6/SLAMF6/LY9/IRF4 |
5 |
| BP |
GO:0002708 |
positive regulation of lymphocyte mediated immunity |
11/364 |
119/18903 |
1.91E-05 |
0.0003523 |
0.0002833 |
FCGR1A/HLA-DRA/IL6/SLAMF6/SLAMF1/CRTAM/XCL1/RASGRP1/CLNK/IL1B/AZGP1 |
11 |
| BP |
GO:0002825 |
regulation of T-helper 1 type immune response |
6/364 |
30/18903 |
1.97E-05 |
0.0003603 |
0.0002897 |
CD80/SLAMF1/CCR2/XCL1/IL1B/CCL19 |
6 |
| BP |
GO:0002437 |
inflammatory response to antigenic stimulus |
9/364 |
79/18903 |
2.07E-05 |
0.0003779 |
0.0003038 |
FCGR1A/FCGR3A/IL10/IL2RA/PLA2G2D/IGHG1/RASGRP1/CCR7/IL1RN |
9 |
| BP |
GO:0030101 |
natural killer cell activation |
10/364 |
99/18903 |
2.11E-05 |
0.0003831 |
0.0003081 |
IL21R/FCGR3A/SLAMF7/SLAMF1/CD2/RASGRP1/CLNK/KLRC1/IFNE/LEP |
10 |
| BP |
GO:0070227 |
lymphocyte apoptotic process |
9/364 |
80/18903 |
2.29E-05 |
0.0004147 |
0.0003335 |
IL10/IL2RA/IL7R/IDO1/CD274/FASLG/CD3G/CD27/PDCD1 |
9 |
| BP |
GO:0002820 |
negative regulation of adaptive immune response |
8/364 |
62/18903 |
2.39E-05 |
0.0004235 |
0.0003405 |
SAMSN1/SLAMF1/IL7R/CR1/IL4I1/XCL1/KLRC1/CR2 |
8 |
| BP |
GO:0002507 |
tolerance induction |
6/364 |
31/18903 |
2.40E-05 |
0.0004235 |
0.0003405 |
IL2RA/ICOS/CCR4/IDO1/CD274/PDCD1 |
6 |
| BP |
GO:0002544 |
chronic inflammatory response |
5/364 |
19/18903 |
2.40E-05 |
0.0004235 |
0.0003405 |
CXCL13/IL10/S100A9/IDO1/S100A8 |
5 |
| BP |
GO:0032695 |
negative regulation of interleukin-12 production |
5/364 |
19/18903 |
2.40E-05 |
0.0004235 |
0.0003405 |
IL10/SLAMF1/TLR8/TIGIT/CCR7 |
5 |
| BP |
GO:0048245 |
eosinophil chemotaxis |
5/364 |
19/18903 |
2.40E-05 |
0.0004235 |
0.0003405 |
CCL4/CCL3/CCL7/CCL8/CCL13 |
5 |
| BP |
GO:0002361 |
CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation |
4/364 |
10/18903 |
2.59E-05 |
0.0004535 |
0.0003646 |
HLA-DRA/PLA2G2D/IFNG/IL2RG |
4 |
| BP |
GO:0035747 |
natural killer cell chemotaxis |
4/364 |
10/18903 |
2.59E-05 |
0.0004535 |
0.0003646 |
CCL4/CCL3/CCL7/XCL1 |
4 |
| BP |
GO:0032677 |
regulation of interleukin-8 production |
10/364 |
103/18903 |
2.98E-05 |
0.00052 |
0.0004181 |
LBP/IL10/IL6/CHI3L1/CD2/TLR8/IL1B/FCN1/LEP/ADIPOQ |
10 |
| BP |
GO:1902622 |
regulation of neutrophil migration |
7/364 |
47/18903 |
3.00E-05 |
0.0005208 |
0.0004188 |
LBP/SLAMF8/TNFAIP6/XCL1/RHOH/CCR7/CCL19 |
7 |
| BP |
GO:0019730 |
antimicrobial humoral response |
11/364 |
125/18903 |
3.04E-05 |
0.0005241 |
0.0004214 |
CXCL6/CXCL1/CXCL13/CXCL3/LYZ/CXCL10/CXCL2/S100A9/CXCL11/CXCL9/CCL13 |
11 |
| BP |
GO:0032637 |
interleukin-8 production |
10/364 |
104/18903 |
3.25E-05 |
0.000558 |
0.0004487 |
LBP/IL10/IL6/CHI3L1/CD2/TLR8/IL1B/FCN1/LEP/ADIPOQ |
10 |
| BP |
GO:0032760 |
positive regulation of tumor necrosis factor production |
10/364 |
105/18903 |
3.53E-05 |
0.0006037 |
0.0004854 |
LBP/CCL3/FCGR3A/IL6/CD2/IFNG/CCR2/RASGRP1/CCL19/LEP |
10 |
| BP |
GO:0010001 |
glial cell differentiation |
15/364 |
227/18903 |
3.62E-05 |
0.0006171 |
0.0004962 |
MYOC/CXCR4/IL6/MAPT/LGI4/IFNG/S100A9/CDK1/KLF15/IL1B/S100A8/EOMES/SOX10/CNTN2/KCNJ10 |
15 |
| BP |
GO:0001818 |
negative regulation of cytokine production |
20/364 |
371/18903 |
3.73E-05 |
0.0006322 |
0.0005084 |
LBP/SRGN/IL10/IL6/SLAMF1/WNT11/IFNG/CR1/TLR8/TIGIT/IDO1/CD274/CD96/XCL1/CCR7/GPR18/LILRA4/APOD/CIDEA/ADIPOQ |
20 |
| BP |
GO:0031343 |
positive regulation of cell killing |
8/364 |
66/18903 |
3.80E-05 |
0.0006412 |
0.0005156 |
HLA-DRA/SLAMF6/CRTAM/IFNG/XCL1/RASGRP1/STAP1/AZGP1 |
8 |
| BP |
GO:0070189 |
kynurenine metabolic process |
4/364 |
11/18903 |
4.01E-05 |
0.0006742 |
0.0005421 |
KMO/KYNU/IDO1/TDO2 |
4 |
| BP |
GO:0043373 |
CD4-positive, alpha-beta T cell lineage commitment |
5/364 |
21/18903 |
4.07E-05 |
0.0006805 |
0.0005472 |
BATF/IL6/SLAMF6/LY9/IRF4 |
5 |
| BP |
GO:0019932 |
second-messenger-mediated signaling |
18/364 |
314/18903 |
4.12E-05 |
0.0006871 |
0.0005525 |
CCL4/CCL3/CCR5/FCGR3A/CXCR4/MAPT/SELE/FPR1/CCR4/ATP1A2/CXCR6/TRAT1/CCR2/CCR7/FPR2/BHLHA15/CCL20/PDE11A |
18 |
| BP |
GO:0002444 |
myeloid leukocyte mediated immunity |
10/364 |
107/18903 |
4.15E-05 |
0.0006893 |
0.0005542 |
CXCL6/FCGR1A/CCL3/FCGR3A/IL6/CCR2/IGHG1/RASGRP1/CLNK/STAP1 |
10 |
| BP |
GO:0019882 |
antigen processing and presentation |
10/364 |
108/18903 |
4.50E-05 |
0.0007436 |
0.0005979 |
FCGR1A/HLA-DQA1/HLA-DRA/IFI30/HLA-DOB/CCR7/HLA-DQB2/CCL19/AZGP1/KDM5D |
10 |
| BP |
GO:0042093 |
T-helper cell differentiation |
8/364 |
68/18903 |
4.73E-05 |
0.0007777 |
0.0006253 |
CD80/HLA-DRA/BATF/IL6/SLAMF6/LY9/IRF4/CCL19 |
8 |
| BP |
GO:1903557 |
positive regulation of tumor necrosis factor superfamily cytokine production |
10/364 |
109/18903 |
4.87E-05 |
0.0007981 |
0.0006417 |
LBP/CCL3/FCGR3A/IL6/CD2/IFNG/CCR2/RASGRP1/CCL19/LEP |
10 |
| BP |
GO:0032611 |
interleukin-1 beta production |
10/364 |
111/18903 |
5.69E-05 |
0.0009247 |
0.0007436 |
CCL3/AIM2/IL6/IFNG/TLR8/GBP5/NLRP2/CCR7/PYHIN1/CCL19 |
10 |
| BP |
GO:0032651 |
regulation of interleukin-1 beta production |
10/364 |
111/18903 |
5.69E-05 |
0.0009247 |
0.0007436 |
CCL3/AIM2/IL6/IFNG/TLR8/GBP5/NLRP2/CCR7/PYHIN1/CCL19 |
10 |
| BP |
GO:0045589 |
regulation of regulatory T cell differentiation |
6/364 |
36/18903 |
5.85E-05 |
0.0009459 |
0.0007606 |
HLA-DRA/CTLA4/IFNG/CR1/IL2RG/IL4I1 |
6 |
| BP |
GO:0002363 |
alpha-beta T cell lineage commitment |
5/364 |
23/18903 |
6.51E-05 |
0.0010405 |
0.0008366 |
BATF/IL6/SLAMF6/LY9/IRF4 |
5 |
| BP |
GO:0045591 |
positive regulation of regulatory T cell differentiation |
5/364 |
23/18903 |
6.51E-05 |
0.0010405 |
0.0008366 |
HLA-DRA/IFNG/CR1/IL2RG/IL4I1 |
5 |
| BP |
GO:0072677 |
eosinophil migration |
5/364 |
23/18903 |
6.51E-05 |
0.0010405 |
0.0008366 |
CCL4/CCL3/CCL7/CCL8/CCL13 |
5 |
| BP |
GO:0002221 |
pattern recognition receptor signaling pathway |
13/364 |
187/18903 |
7.12E-05 |
0.0011271 |
0.0009063 |
LBP/AIM2/CD300LF/TNIP3/TLR8/BIRC3/TLR10/FCRL3/IRF4/LILRA4/SMPDL3B/CLEC4E/FCN1 |
13 |
| BP |
GO:0002526 |
acute inflammatory response |
10/364 |
114/18903 |
7.14E-05 |
0.0011271 |
0.0009063 |
FCGR1A/LBP/FCGR3A/IL6/PLA2G2D/OSM/IGHG1/IL1B/CCR7/S100A8 |
10 |
| BP |
GO:0002824 |
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains |
10/364 |
114/18903 |
7.14E-05 |
0.0011271 |
0.0009063 |
FCGR1A/HLA-DRA/IL6/SLAMF1/CCR2/CD274/XCL1/IL1B/CLEC6A/AZGP1 |
10 |
| BP |
GO:0046395 |
carboxylic acid catabolic process |
15/364 |
243/18903 |
7.87E-05 |
0.0012275 |
0.0009871 |
KMO/KYNU/IDO1/TDO2/IL4I1/SDS/ALDH1L1/MAT1A/ACADL/GPT/ACOXL/PLIN5/LEP/ADIPOQ/PCK1 |
15 |
| BP |
GO:0046635 |
positive regulation of alpha-beta T cell activation |
8/364 |
73/18903 |
7.91E-05 |
0.0012275 |
0.0009871 |
CD80/HLA-DRA/ZBTB16/IFNG/IL2RG/CCR2/XCL1/CCL19 |
8 |
| BP |
GO:0046637 |
regulation of alpha-beta T cell differentiation |
8/364 |
73/18903 |
7.91E-05 |
0.0012275 |
0.0009871 |
CD80/HLA-DRA/ZBTB16/BATF/IFNG/IL2RG/IRF4/CCL19 |
8 |
| BP |
GO:0050805 |
negative regulation of synaptic transmission |
8/364 |
73/18903 |
7.91E-05 |
0.0012275 |
0.0009871 |
MAPT/CD38/GRIA1/IL1B/GRIK3/CNR2/SHANK2/ADIPOQ |
8 |
| BP |
GO:0042092 |
type 2 immune response |
6/364 |
38/18903 |
8.02E-05 |
0.0012406 |
0.0009976 |
BATF/IL10/IL6/IDO1/CCR2/XCL1 |
6 |
| BP |
GO:0042430 |
indole-containing compound metabolic process |
5/364 |
24/18903 |
8.10E-05 |
0.0012421 |
0.0009988 |
KMO/KYNU/IDO1/TDO2/IL4I1 |
5 |
| BP |
GO:0043369 |
CD4-positive or CD8-positive, alpha-beta T cell lineage commitment |
5/364 |
24/18903 |
8.10E-05 |
0.0012421 |
0.0009988 |
BATF/IL6/SLAMF6/LY9/IRF4 |
5 |
| BP |
GO:0002430 |
complement receptor mediated signaling pathway |
4/364 |
13/18903 |
8.43E-05 |
0.0012824 |
0.0010311 |
CR1/FPR1/CR2/FPR2 |
4 |
| BP |
GO:0002524 |
hypersensitivity |
4/364 |
13/18903 |
8.43E-05 |
0.0012824 |
0.0010311 |
FCGR1A/FCGR3A/IGHG1/CCR7 |
4 |
| BP |
GO:0002686 |
negative regulation of leukocyte migration |
7/364 |
55/18903 |
8.49E-05 |
0.0012873 |
0.0010351 |
SLAMF8/TNFAIP6/GCSAM/GPR18/STAP1/BMP5/APOD |
7 |
| BP |
GO:0002381 |
immunoglobulin production involved in immunoglobulin-mediated immune response |
8/364 |
74/18903 |
8.72E-05 |
0.0013164 |
0.0010585 |
HLA-DQA1/HLA-DRA/BATF/IL10/HLA-DOB/XCL1/GAPT/HLA-DQB2 |
8 |
| BP |
GO:0016054 |
organic acid catabolic process |
15/364 |
247/18903 |
9.45E-05 |
0.0014215 |
0.0011431 |
KMO/KYNU/IDO1/TDO2/IL4I1/SDS/ALDH1L1/MAT1A/ACADL/GPT/ACOXL/PLIN5/LEP/ADIPOQ/PCK1 |
15 |
| BP |
GO:0043370 |
regulation of CD4-positive, alpha-beta T cell differentiation |
7/364 |
56/18903 |
9.55E-05 |
0.0014247 |
0.0011456 |
CD80/HLA-DRA/BATF/IFNG/IL2RG/IRF4/CCL19 |
7 |
| BP |
GO:0050832 |
defense response to fungus |
7/364 |
56/18903 |
9.55E-05 |
0.0014247 |
0.0011456 |
S100A9/CLEC4D/ZBP1/CLEC4C/CLEC6A/S100A8/CLEC4E |
7 |
| BP |
GO:0034114 |
regulation of heterotypic cell-cell adhesion |
5/364 |
25/18903 |
9.96E-05 |
0.001481 |
0.0011909 |
IL10/IL1B/LCK/IL1RN/ADIPOQ |
5 |
| BP |
GO:0002823 |
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains |
7/364 |
57/18903 |
0.0001071 |
0.0015792 |
0.0012699 |
SLAMF1/IL7R/CR1/IL4I1/XCL1/KLRC1/CR2 |
7 |
| BP |
GO:0070231 |
T cell apoptotic process |
7/364 |
57/18903 |
0.0001071 |
0.0015792 |
0.0012699 |
IL2RA/IL7R/IDO1/CD274/FASLG/CD27/PDCD1 |
7 |
| BP |
GO:0002478 |
antigen processing and presentation of exogenous peptide antigen |
6/364 |
40/18903 |
0.000108 |
0.001581 |
0.0012713 |
FCGR1A/HLA-DQA1/HLA-DRA/IFI30/HLA-DOB/HLA-DQB2 |
6 |
| BP |
GO:0006882 |
cellular zinc ion homeostasis |
6/364 |
40/18903 |
0.000108 |
0.001581 |
0.0012713 |
SLC39A8/S100A9/S100A8/LCK/MT1G/MT1H |
6 |
| BP |
GO:0002821 |
positive regulation of adaptive immune response |
10/364 |
120/18903 |
0.00011 |
0.0016047 |
0.0012903 |
FCGR1A/HLA-DRA/IL6/SLAMF1/CCR2/CD274/XCL1/IL1B/CLEC6A/AZGP1 |
10 |
| BP |
GO:0032729 |
positive regulation of interferon-gamma production |
8/364 |
77/18903 |
0.0001158 |
0.0016822 |
0.0013527 |
SLAMF6/SLAMF1/CRTAM/CD2/TLR8/CCR2/RASGRP1/IL1B |
8 |
| BP |
GO:0002438 |
acute inflammatory response to antigenic stimulus |
5/364 |
26/18903 |
0.0001214 |
0.0017508 |
0.0014078 |
FCGR1A/FCGR3A/PLA2G2D/IGHG1/CCR7 |
5 |
| BP |
GO:0046629 |
gamma-delta T cell activation |
5/364 |
26/18903 |
0.0001214 |
0.0017508 |
0.0014078 |
ITK/KLRC1/GPR18/CD3G/TRGC2 |
5 |
| BP |
GO:0051281 |
positive regulation of release of sequestered calcium ion into cytosol |
6/364 |
41/18903 |
0.0001245 |
0.0017883 |
0.001438 |
CXCL10/CXCL11/CXCL9/XCL1/CD19/JPH2 |
6 |
| BP |
GO:0001912 |
positive regulation of leukocyte mediated cytotoxicity |
7/364 |
59/18903 |
0.0001337 |
0.0019131 |
0.0015383 |
HLA-DRA/SLAMF6/CRTAM/XCL1/RASGRP1/STAP1/AZGP1 |
7 |
| BP |
GO:0001776 |
leukocyte homeostasis |
9/364 |
100/18903 |
0.0001343 |
0.0019157 |
0.0015404 |
CXCL6/IL6/IL2RA/IL7R/GPR174/TNFRSF17/GAPT/SIT1/LGALS2 |
9 |
| BP |
GO:0002224 |
toll-like receptor signaling pathway |
10/364 |
123/18903 |
0.0001352 |
0.0019203 |
0.0015441 |
LBP/CD300LF/TNIP3/TLR8/BIRC3/TLR10/FCRL3/IRF4/LILRA4/SMPDL3B |
10 |
| BP |
GO:1903556 |
negative regulation of tumor necrosis factor superfamily cytokine production |
8/364 |
79/18903 |
0.0001389 |
0.0019654 |
0.0015804 |
LBP/IL10/SLAMF1/CD274/GPR18/LILRA4/CIDEA/ADIPOQ |
8 |
| BP |
GO:0014002 |
astrocyte development |
6/364 |
42/18903 |
0.0001429 |
0.0020079 |
0.0016145 |
IL6/MAPT/IFNG/S100A9/IL1B/S100A8 |
6 |
| BP |
GO:0055069 |
zinc ion homeostasis |
6/364 |
42/18903 |
0.0001429 |
0.0020079 |
0.0016145 |
SLC39A8/S100A9/S100A8/LCK/MT1G/MT1H |
6 |
| BP |
GO:0002710 |
negative regulation of T cell mediated immunity |
5/364 |
27/18903 |
0.0001467 |
0.0020313 |
0.0016334 |
SLAMF1/IL7R/IL4I1/XCL1/KLRC1 |
5 |
| BP |
GO:0036037 |
CD8-positive, alpha-beta T cell activation |
5/364 |
27/18903 |
0.0001467 |
0.0020313 |
0.0016334 |
CRTAM/CD274/XCL1/GPR18/EOMES |
5 |
| BP |
GO:0042537 |
benzene-containing compound metabolic process |
5/364 |
27/18903 |
0.0001467 |
0.0020313 |
0.0016334 |
KMO/KYNU/CYP4B1/IDO1/TDO2 |
5 |
| BP |
GO:0070269 |
pyroptosis |
5/364 |
27/18903 |
0.0001467 |
0.0020313 |
0.0016334 |
AIM2/GZMA/GZMB/ZBP1/GSDMC |
5 |
| BP |
GO:0034113 |
heterotypic cell-cell adhesion |
7/364 |
61/18903 |
0.0001654 |
0.0022825 |
0.0018353 |
IL10/ITGA4/CD2/IL1B/LCK/IL1RN/ADIPOQ |
7 |
| BP |
GO:0002675 |
positive regulation of acute inflammatory response |
5/364 |
28/18903 |
0.0001758 |
0.0024167 |
0.0019433 |
FCGR1A/IL6/OSM/IL1B/CCR7 |
5 |
| BP |
GO:0048708 |
astrocyte differentiation |
8/364 |
82/18903 |
0.0001805 |
0.0024724 |
0.001988 |
IL6/MAPT/IFNG/S100A9/IL1B/S100A8/EOMES/CNTN2 |
8 |
| BP |
GO:0070228 |
regulation of lymphocyte apoptotic process |
7/364 |
62/18903 |
0.0001834 |
0.0025041 |
0.0020135 |
IL10/IL7R/IDO1/CD274/CD3G/CD27/PDCD1 |
7 |
| BP |
GO:0032689 |
negative regulation of interferon-gamma production |
6/364 |
44/18903 |
0.0001862 |
0.0025238 |
0.0020294 |
IL10/SLAMF1/CR1/CD274/CD96/XCL1 |
6 |
| BP |
GO:0072538 |
T-helper 17 type immune response |
6/364 |
44/18903 |
0.0001862 |
0.0025238 |
0.0020294 |
BATF/IL6/SLAMF6/LY9/IRF4/CLEC6A |
6 |
| BP |
GO:0002399 |
MHC class II protein complex assembly |
4/364 |
16/18903 |
0.0002049 |
0.0027487 |
0.0022102 |
HLA-DQA1/HLA-DRA/HLA-DOB/HLA-DQB2 |
4 |
| BP |
GO:0002503 |
peptide antigen assembly with MHC class II protein complex |
4/364 |
16/18903 |
0.0002049 |
0.0027487 |
0.0022102 |
HLA-DQA1/HLA-DRA/HLA-DOB/HLA-DQB2 |
4 |
| BP |
GO:0010820 |
positive regulation of T cell chemotaxis |
4/364 |
16/18903 |
0.0002049 |
0.0027487 |
0.0022102 |
CXCL13/CCR2/XCL2/XCL1 |
4 |
| BP |
GO:0090025 |
regulation of monocyte chemotaxis |
5/364 |
29/18903 |
0.0002091 |
0.0027946 |
0.0022471 |
SLAMF8/CXCL10/PLA2G7/CCR2/FPR2 |
5 |
| BP |
GO:0031295 |
T cell costimulation |
6/364 |
45/18903 |
0.0002114 |
0.0028061 |
0.0022564 |
CD80/ICOS/CD274/CCR7/LCK/CCL19 |
6 |
| BP |
GO:2000516 |
positive regulation of CD4-positive, alpha-beta T cell activation |
6/364 |
45/18903 |
0.0002114 |
0.0028061 |
0.0022564 |
CD80/HLA-DRA/IFNG/IL2RG/XCL1/CCL19 |
6 |
| BP |
GO:0048002 |
antigen processing and presentation of peptide antigen |
7/364 |
64/18903 |
0.0002242 |
0.0029661 |
0.002385 |
FCGR1A/HLA-DQA1/HLA-DRA/IFI30/HLA-DOB/HLA-DQB2/AZGP1 |
7 |
| BP |
GO:0042088 |
T-helper 1 type immune response |
6/364 |
46/18903 |
0.0002392 |
0.0031535 |
0.0025357 |
CD80/SLAMF1/CCR2/XCL1/IL1B/CCL19 |
6 |
| BP |
GO:0002360 |
T cell lineage commitment |
5/364 |
30/18903 |
0.0002469 |
0.003201 |
0.0025739 |
BATF/IL6/SLAMF6/LY9/IRF4 |
5 |
| BP |
GO:0009072 |
aromatic amino acid family metabolic process |
5/364 |
30/18903 |
0.0002469 |
0.003201 |
0.0025739 |
KMO/KYNU/IDO1/TDO2/IL4I1 |
5 |
| BP |
GO:0019886 |
antigen processing and presentation of exogenous peptide antigen via MHC class II |
5/364 |
30/18903 |
0.0002469 |
0.003201 |
0.0025739 |
HLA-DQA1/HLA-DRA/IFI30/HLA-DOB/HLA-DQB2 |
5 |
| BP |
GO:0072539 |
T-helper 17 cell differentiation |
5/364 |
30/18903 |
0.0002469 |
0.003201 |
0.0025739 |
BATF/IL6/SLAMF6/LY9/IRF4 |
5 |
| BP |
GO:2000108 |
positive regulation of leukocyte apoptotic process |
5/364 |
30/18903 |
0.0002469 |
0.003201 |
0.0025739 |
IL10/IDO1/CD274/PDCD1/MIAT |
5 |
| BP |
GO:0002440 |
production of molecular mediator of immune response |
17/364 |
333/18903 |
0.0002695 |
0.0034507 |
0.0027747 |
HLA-DQA1/HLA-DRA/BATF/IL10/IL6/SLAMF1/CR1/HLA-DOB/CCR2/MZB1/CD96/XCL1/CLNK/FCRL3/IL1B/GAPT/HLA-DQB2 |
17 |
| BP |
GO:0002701 |
negative regulation of production of molecular mediator of immune response |
6/364 |
47/18903 |
0.0002698 |
0.0034507 |
0.0027747 |
IL10/SLAMF1/CR1/CD96/XCL1/FCRL3 |
6 |
| BP |
GO:0031294 |
lymphocyte costimulation |
6/364 |
47/18903 |
0.0002698 |
0.0034507 |
0.0027747 |
CD80/ICOS/CD274/CCR7/LCK/CCL19 |
6 |
| BP |
GO:0042269 |
regulation of natural killer cell mediated cytotoxicity |
6/364 |
47/18903 |
0.0002698 |
0.0034507 |
0.0027747 |
SLAMF6/CRTAM/KLRB1/RASGRP1/KLRC1/LEP |
6 |
| BP |
GO:0050854 |
regulation of antigen receptor-mediated signaling pathway |
7/364 |
66/18903 |
0.000272 |
0.0034671 |
0.0027879 |
TRAT1/GCSAM/FCRL3/CCR7/STAP1/LCK/CD19 |
7 |
| BP |
GO:0002312 |
B cell activation involved in immune response |
8/364 |
88/18903 |
0.0002945 |
0.0037421 |
0.003009 |
CD180/BATF/IL10/IL6/CR1/GAPT/POU2AF1/CD19 |
8 |
| BP |
GO:0009620 |
response to fungus |
7/364 |
67/18903 |
0.0002987 |
0.0037835 |
0.0030423 |
S100A9/CLEC4D/ZBP1/CLEC4C/CLEC6A/S100A8/CLEC4E |
7 |
| BP |
GO:0002673 |
regulation of acute inflammatory response |
6/364 |
48/18903 |
0.0003034 |
0.0038295 |
0.0030793 |
FCGR1A/IL6/PLA2G2D/OSM/IL1B/CCR7 |
6 |
| BP |
GO:0032102 |
negative regulation of response to external stimulus |
20/364 |
436/18903 |
0.0003275 |
0.0041203 |
0.0033132 |
SEMA3B/SLAMF8/CXCL13/IL10/IL2RA/SIGLEC10/CR1/SPP1/PBK/TNFAIP6/CD96/MMP12/KLRC1/GPR18/SMPDL3B/STAP1/FPR2/CNR2/LEP/ADIPOQ |
20 |
| BP |
GO:0002827 |
positive regulation of T-helper 1 type immune response |
4/364 |
18/18903 |
0.0003342 |
0.0041636 |
0.0033479 |
SLAMF1/CCR2/XCL1/IL1B |
4 |
| BP |
GO:0070230 |
positive regulation of lymphocyte apoptotic process |
4/364 |
18/18903 |
0.0003342 |
0.0041636 |
0.0033479 |
IL10/IDO1/CD274/PDCD1 |
4 |
| BP |
GO:0150078 |
positive regulation of neuroinflammatory response |
4/364 |
18/18903 |
0.0003342 |
0.0041636 |
0.0033479 |
CCL3/IL6/IL1B/STAP1 |
4 |
| BP |
GO:0019884 |
antigen processing and presentation of exogenous antigen |
6/364 |
49/18903 |
0.0003402 |
0.0042149 |
0.0033892 |
FCGR1A/HLA-DQA1/HLA-DRA/IFI30/HLA-DOB/HLA-DQB2 |
6 |
| BP |
GO:0007188 |
adenylate cyclase-modulating G protein-coupled receptor signaling pathway |
14/364 |
248/18903 |
0.0003405 |
0.0042149 |
0.0033892 |
GPR65/CXCL10/FPR1/RGS1/ADRA2B/PALM/CXCL11/CXCL9/ADCY5/FPR2/ADRA1A/GRIK3/CNR2/NPY1R |
14 |
| BP |
GO:0002260 |
lymphocyte homeostasis |
7/364 |
69/18903 |
0.0003587 |
0.0044258 |
0.0035588 |
IL2RA/IL7R/GPR174/TNFRSF17/GAPT/SIT1/LGALS2 |
7 |
| BP |
GO:0050852 |
T cell receptor signaling pathway |
10/364 |
139/18903 |
0.0003661 |
0.0045031 |
0.003621 |
CTLA4/CD3D/TRAT1/ITK/THEMIS/CCR7/CD3G/LCK/TRAC/TRGC2 |
10 |
| BP |
GO:0006816 |
calcium ion transport |
20/364 |
440/18903 |
0.0003681 |
0.0045137 |
0.0036295 |
CCL4/CCL3/CCR5/CXCR4/CXCL10/CCL8/ATP1A2/CXCL11/CXCL9/XCL1/FASLG/FCRL3/CCR7/MS4A1/LCK/CCL19/CD19/BHLHA15/ADRA1A/JPH2 |
20 |
| BP |
GO:0050731 |
positive regulation of peptidyl-tyrosine phosphorylation |
12/364 |
193/18903 |
0.0003773 |
0.0046113 |
0.003708 |
FCGR1A/CD80/IL6/OSM/IFNG/CLEC6A/ANGPT4/STAP1/IGF2/ADRA1A/LEP/ADIPOQ |
12 |
| BP |
GO:0043087 |
regulation of GTPase activity |
18/364 |
376/18903 |
0.0003902 |
0.0047535 |
0.0038223 |
CCL4/CCL18/CCL3/GPR65/RGS6/CXCL13/WNT11/CCL7/CCL8/RGS1/TGM2/XCL2/XCL1/RASGRP1/CCR7/CCL13/CCL19/CCL20 |
18 |
| BP |
GO:0038094 |
Fc-gamma receptor signaling pathway |
5/364 |
33/18903 |
0.0003922 |
0.0047638 |
0.0038306 |
FCGR1A/FCGR3A/CLEC4D/LCK/CLEC4E |
5 |
| BP |
GO:0035743 |
CD4-positive, alpha-beta T cell cytokine production |
4/364 |
19/18903 |
0.0004169 |
0.0050314 |
0.0040457 |
IL6/SLAMF1/XCL1/IL1B |
4 |
| BP |
GO:0071625 |
vocalization behavior |
4/364 |
19/18903 |
0.0004169 |
0.0050314 |
0.0040457 |
MYH14/TIFAB/NRXN1/SHANK2 |
4 |
| BP |
GO:0001913 |
T cell mediated cytotoxicity |
6/364 |
51/18903 |
0.0004242 |
0.0051035 |
0.0041037 |
HLA-DRA/IL7R/XCL1/TRA/KLRC1/AZGP1 |
6 |
| BP |
GO:0018108 |
peptidyl-tyrosine phosphorylation |
18/364 |
380/18903 |
0.0004423 |
0.0053045 |
0.0042654 |
FCGR1A/SAMSN1/CD80/IL6/TTK/OSM/IFNG/PBK/MELK/ITK/CLEC6A/ANGPT4/STAP1/LCK/IGF2/ADRA1A/LEP/ADIPOQ |
18 |
| BP |
GO:0002495 |
antigen processing and presentation of peptide antigen via MHC class II |
5/364 |
34/18903 |
0.0004527 |
0.0053957 |
0.0043387 |
HLA-DQA1/HLA-DRA/IFI30/HLA-DOB/HLA-DQB2 |
5 |
| BP |
GO:0090022 |
regulation of neutrophil chemotaxis |
5/364 |
34/18903 |
0.0004527 |
0.0053957 |
0.0043387 |
LBP/TNFAIP6/XCL1/CCR7/CCL19 |
5 |
| BP |
GO:0018212 |
peptidyl-tyrosine modification |
18/364 |
382/18903 |
0.0004705 |
0.0055895 |
0.0044945 |
FCGR1A/SAMSN1/CD80/IL6/TTK/OSM/IFNG/PBK/MELK/ITK/CLEC6A/ANGPT4/STAP1/LCK/IGF2/ADRA1A/LEP/ADIPOQ |
18 |
| BP |
GO:0006968 |
cellular defense response |
6/364 |
52/18903 |
0.0004718 |
0.0055895 |
0.0044945 |
LBP/CCR5/TRAT1/CCR2/CXCL9/ITK |
6 |
| BP |
GO:1901606 |
alpha-amino acid catabolic process |
8/364 |
95/18903 |
0.0004958 |
0.0058551 |
0.0047081 |
KMO/KYNU/IDO1/TDO2/IL4I1/SDS/MAT1A/GPT |
8 |
| BP |
GO:0150076 |
neuroinflammatory response |
7/364 |
73/18903 |
0.0005072 |
0.0059619 |
0.004794 |
MMP3/CCL3/IL6/MAPT/IFNG/IL1B/STAP1 |
7 |
| BP |
GO:0002396 |
MHC protein complex assembly |
4/364 |
20/18903 |
0.0005132 |
0.0059619 |
0.004794 |
HLA-DQA1/HLA-DRA/HLA-DOB/HLA-DQB2 |
4 |
| BP |
GO:0002501 |
peptide antigen assembly with MHC protein complex |
4/364 |
20/18903 |
0.0005132 |
0.0059619 |
0.004794 |
HLA-DQA1/HLA-DRA/HLA-DOB/HLA-DQB2 |
4 |
| BP |
GO:0002643 |
regulation of tolerance induction |
4/364 |
20/18903 |
0.0005132 |
0.0059619 |
0.004794 |
IL2RA/IDO1/CD274/PDCD1 |
4 |
| BP |
GO:1903975 |
regulation of glial cell migration |
4/364 |
20/18903 |
0.0005132 |
0.0059619 |
0.004794 |
CCL3/CCR2/NTN1/STAP1 |
4 |
| BP |
GO:0043270 |
positive regulation of ion transport |
15/364 |
289/18903 |
0.0005141 |
0.0059619 |
0.004794 |
CCL4/KMO/CCL3/CXCL10/IFNG/CCR2/CXCL11/CXCL9/XCL1/WNK2/IL1B/MS4A1/CD19/JPH2/LEP |
15 |
| BP |
GO:0043372 |
positive regulation of CD4-positive, alpha-beta T cell differentiation |
5/364 |
35/18903 |
0.0005199 |
0.0060105 |
0.0048331 |
CD80/HLA-DRA/IFNG/IL2RG/CCL19 |
5 |
| BP |
GO:0046638 |
positive regulation of alpha-beta T cell differentiation |
6/364 |
53/18903 |
0.0005236 |
0.0060171 |
0.0048384 |
CD80/HLA-DRA/ZBTB16/IFNG/IL2RG/CCL19 |
6 |
| BP |
GO:0071622 |
regulation of granulocyte chemotaxis |
6/364 |
53/18903 |
0.0005236 |
0.0060171 |
0.0048384 |
LBP/SLAMF1/TNFAIP6/XCL1/CCR7/CCL19 |
6 |
| BP |
GO:0051897 |
positive regulation of protein kinase B signaling |
9/364 |
120/18903 |
0.0005279 |
0.0060484 |
0.0048635 |
CCL3/MYOC/CHI3L1/OSM/CCR7/F10/CCL19/IGF2/LEP |
9 |
| BP |
GO:0061900 |
glial cell activation |
6/364 |
54/18903 |
0.0005796 |
0.0066215 |
0.0053243 |
CCL3/IL6/MAPT/IFNG/IL1B/STAP1 |
6 |
| BP |
GO:0002504 |
antigen processing and presentation of peptide or polysaccharide antigen via MHC class II |
5/364 |
36/18903 |
0.0005943 |
0.0067693 |
0.0054432 |
HLA-DQA1/HLA-DRA/IFI30/HLA-DOB/HLA-DQB2 |
5 |
| BP |
GO:0032642 |
regulation of chemokine production |
8/364 |
98/18903 |
0.0006107 |
0.0069151 |
0.0055605 |
CXCL6/LBP/IL10/IL6/IFNG/IL1B/APOD/ADIPOQ |
8 |
| BP |
GO:0120162 |
positive regulation of cold-induced thermogenesis |
8/364 |
98/18903 |
0.0006107 |
0.0069151 |
0.0055605 |
CXCR4/CCR2/IRF4/PLAC8/ACADL/LEP/FABP4/ADIPOQ |
8 |
| BP |
GO:0090026 |
positive regulation of monocyte chemotaxis |
4/364 |
21/18903 |
0.0006244 |
0.0070501 |
0.005669 |
CXCL10/PLA2G7/CCR2/FPR2 |
4 |
| BP |
GO:0038093 |
Fc receptor signaling pathway |
6/364 |
55/18903 |
0.0006402 |
0.0071855 |
0.0057779 |
FCGR1A/FCGR3A/CLEC4D/LILRA4/LCK/CLEC4E |
6 |
| BP |
GO:2000107 |
negative regulation of leukocyte apoptotic process |
6/364 |
55/18903 |
0.0006402 |
0.0071855 |
0.0057779 |
IL7R/IDO1/CCR7/CD27/CCL19/PDCD1 |
6 |
| BP |
GO:0032602 |
chemokine production |
8/364 |
99/18903 |
0.0006534 |
0.0073133 |
0.0058806 |
CXCL6/LBP/IL10/IL6/IFNG/IL1B/APOD/ADIPOQ |
8 |
| BP |
GO:0032720 |
negative regulation of tumor necrosis factor production |
7/364 |
77/18903 |
0.0007012 |
0.0078019 |
0.0062735 |
LBP/IL10/SLAMF1/GPR18/LILRA4/CIDEA/ADIPOQ |
7 |
| BP |
GO:0034121 |
regulation of toll-like receptor signaling pathway |
7/364 |
77/18903 |
0.0007012 |
0.0078019 |
0.0062735 |
LBP/CD300LF/BIRC3/FCRL3/IRF4/LILRA4/SMPDL3B |
7 |
| BP |
GO:0002369 |
T cell cytokine production |
5/364 |
38/18903 |
0.0007667 |
0.0084775 |
0.0068168 |
IL6/SLAMF1/CCR2/XCL1/IL1B |
5 |
| BP |
GO:0002724 |
regulation of T cell cytokine production |
5/364 |
38/18903 |
0.0007667 |
0.0084775 |
0.0068168 |
IL6/SLAMF1/CCR2/XCL1/IL1B |
5 |
| BP |
GO:2000659 |
regulation of interleukin-1-mediated signaling pathway |
3/364 |
10/18903 |
0.0007685 |
0.0084775 |
0.0068168 |
IL6/ZBP1/IL1RN |
3 |
| BP |
GO:0031348 |
negative regulation of defense response |
14/364 |
272/18903 |
0.0008491 |
0.0093398 |
0.0075101 |
SLAMF8/IL10/IL2RA/SIGLEC10/CR1/PBK/TNFAIP6/CD96/MMP12/KLRC1/SMPDL3B/FPR2/CNR2/ADIPOQ |
14 |
| BP |
GO:0050871 |
positive regulation of B cell activation |
10/364 |
155/18903 |
0.0008602 |
0.0094357 |
0.0075873 |
IL10/IL6/CD38/IL2RG/IGHG1/IGLL5/FCRL3/CD27/IGHE/IGHD |
10 |
| BP |
GO:0051928 |
positive regulation of calcium ion transport |
9/364 |
129/18903 |
0.0008898 |
0.0097197 |
0.0078156 |
CCL4/CCL3/CXCL10/CXCL11/CXCL9/XCL1/MS4A1/CD19/JPH2 |
9 |
| BP |
GO:0002689 |
negative regulation of leukocyte chemotaxis |
4/364 |
23/18903 |
0.0008962 |
0.0097197 |
0.0078156 |
SLAMF8/TNFAIP6/GPR18/STAP1 |
4 |
| BP |
GO:0048143 |
astrocyte activation |
4/364 |
23/18903 |
0.0008962 |
0.0097197 |
0.0078156 |
IL6/MAPT/IFNG/IL1B |
4 |
| BP |
GO:0061760 |
antifungal innate immune response |
4/364 |
23/18903 |
0.0008962 |
0.0097197 |
0.0078156 |
CLEC4D/CLEC4C/CLEC6A/CLEC4E |
4 |
| BP |
GO:0048545 |
response to steroid hormone |
16/364 |
339/18903 |
0.0009419 |
0.0101858 |
0.0081904 |
IL10/IL6/GJB2/SPP1/CD38/ATP1A2/PCSK1/RXRG/SLC12A3/SOX10/IL1RN/SDC1/ADIPOQ/CSN1S1/PCK1/KDM5D |
16 |
| BP |
GO:0007200 |
phospholipase C-activating G protein-coupled receptor signaling pathway |
8/364 |
105/18903 |
0.0009635 |
0.0103903 |
0.0083548 |
GPR65/FPR1/TGM2/P2RY10/GPR174/GPR18/FPR2/ADRA1A |
8 |
| BP |
GO:0002711 |
positive regulation of T cell mediated immunity |
6/364 |
60/18903 |
0.00102 |
0.0109535 |
0.0088077 |
HLA-DRA/IL6/SLAMF1/XCL1/IL1B/AZGP1 |
6 |
| BP |
GO:0051279 |
regulation of release of sequestered calcium ion into cytosol |
7/364 |
82/18903 |
0.0010214 |
0.0109535 |
0.0088077 |
CXCL10/ATP1A2/CXCL11/CXCL9/XCL1/CD19/JPH2 |
7 |
| BP |
GO:0002700 |
regulation of production of molecular mediator of immune response |
11/364 |
187/18903 |
0.001034 |
0.0110475 |
0.0088833 |
IL10/IL6/SLAMF1/CR1/CCR2/MZB1/CD96/XCL1/CLNK/FCRL3/IL1B |
11 |
| BP |
GO:0033089 |
positive regulation of T cell differentiation in thymus |
3/364 |
11/18903 |
0.0010416 |
0.0110475 |
0.0088833 |
IL7R/IL2RG/RASGRP1 |
3 |
| BP |
GO:0034115 |
negative regulation of heterotypic cell-cell adhesion |
3/364 |
11/18903 |
0.0010416 |
0.0110475 |
0.0088833 |
IL10/IL1RN/ADIPOQ |
3 |
| BP |
GO:0070587 |
regulation of cell-cell adhesion involved in gastrulation |
3/364 |
11/18903 |
0.0010416 |
0.0110475 |
0.0088833 |
IL10/IL1RN/ADIPOQ |
3 |
| BP |
GO:0006956 |
complement activation |
9/364 |
132/18903 |
0.0010477 |
0.011081 |
0.0089103 |
CR1/IGHG1/IGLL5/IL1B/CR2/FCN1/IGHE/C6/IGHD |
9 |
| BP |
GO:0050855 |
regulation of B cell receptor signaling pathway |
4/364 |
24/18903 |
0.0010593 |
0.0111427 |
0.0089599 |
GCSAM/FCRL3/STAP1/CD19 |
4 |
| BP |
GO:0071676 |
negative regulation of mononuclear cell migration |
4/364 |
24/18903 |
0.0010593 |
0.0111427 |
0.0089599 |
SLAMF8/GCSAM/BMP5/APOD |
4 |
| BP |
GO:0001914 |
regulation of T cell mediated cytotoxicity |
5/364 |
41/18903 |
0.001092 |
0.011363 |
0.009137 |
HLA-DRA/IL7R/XCL1/KLRC1/AZGP1 |
5 |
| BP |
GO:0032733 |
positive regulation of interleukin-10 production |
5/364 |
41/18903 |
0.001092 |
0.011363 |
0.009137 |
IL6/TIGIT/CD274/XCL1/IRF4 |
5 |
| BP |
GO:0070232 |
regulation of T cell apoptotic process |
5/364 |
41/18903 |
0.001092 |
0.011363 |
0.009137 |
IL7R/IDO1/CD274/CD27/PDCD1 |
5 |
| BP |
GO:0150077 |
regulation of neuroinflammatory response |
5/364 |
41/18903 |
0.001092 |
0.011363 |
0.009137 |
MMP3/CCL3/IL6/IL1B/STAP1 |
5 |
| BP |
GO:0070588 |
calcium ion transmembrane transport |
16/364 |
345/18903 |
0.0011314 |
0.0117413 |
0.0094412 |
CCL3/CCR5/CXCL10/ATP1A2/CXCL11/CXCL9/XCL1/FASLG/CCR7/MS4A1/LCK/CCL19/CD19/BHLHA15/ADRA1A/JPH2 |
16 |
| BP |
GO:0002377 |
immunoglobulin production |
12/364 |
219/18903 |
0.0011507 |
0.0119086 |
0.0095757 |
HLA-DQA1/HLA-DRA/BATF/IL10/IL6/CR1/HLA-DOB/MZB1/XCL1/FCRL3/GAPT/HLA-DQB2 |
12 |
| BP |
GO:0019216 |
regulation of lipid metabolic process |
16/364 |
347/18903 |
0.0012014 |
0.0124006 |
0.0099713 |
IFNG/IL1B/CCR7/CCL19/BMP5/APOD/CD19/ACADL/PLIN5/LGALS12/CIDEA/THRSP/LEP/MLXIPL/ADIPOQ/PCK1 |
16 |
| BP |
GO:0032735 |
positive regulation of interleukin-12 production |
5/364 |
42/18903 |
0.0012203 |
0.012495 |
0.0100472 |
IFNG/IDO1/CCR7/CCL19/LEP |
5 |
| BP |
GO:0032814 |
regulation of natural killer cell activation |
5/364 |
42/18903 |
0.0012203 |
0.012495 |
0.0100472 |
FCGR3A/RASGRP1/CLNK/KLRC1/LEP |
5 |
| BP |
GO:0043029 |
T cell homeostasis |
5/364 |
42/18903 |
0.0012203 |
0.012495 |
0.0100472 |
IL2RA/IL7R/GPR174/SIT1/LGALS2 |
5 |
| BP |
GO:0042116 |
macrophage activation |
8/364 |
109/18903 |
0.0012287 |
0.0125474 |
0.0100893 |
LBP/CCL3/FCGR3A/IL10/IL6/MAPT/IFNG/STAP1 |
8 |
| BP |
GO:0090023 |
positive regulation of neutrophil chemotaxis |
4/364 |
25/18903 |
0.0012421 |
0.0126507 |
0.0101725 |
LBP/XCL1/CCR7/CCL19 |
4 |
| BP |
GO:0097305 |
response to alcohol |
13/364 |
253/18903 |
0.0013067 |
0.0132743 |
0.0106739 |
CCL3/CCR5/CCL7/CDK1/ADCY5/SLC2A4/CCR7/S100A8/SLC12A3/CCL19/LEP/ADIPOQ/CSN1S1 |
13 |
| BP |
GO:0032623 |
interleukin-2 production |
6/364 |
63/18903 |
0.0013192 |
0.0133307 |
0.0107192 |
CD80/CR1/CCR2/XCL1/IL1B/IRF4 |
6 |
| BP |
GO:0032663 |
regulation of interleukin-2 production |
6/364 |
63/18903 |
0.0013192 |
0.0133307 |
0.0107192 |
CD80/CR1/CCR2/XCL1/IL1B/IRF4 |
6 |
| BP |
GO:0033077 |
T cell differentiation in thymus |
7/364 |
86/18903 |
0.0013522 |
0.0136283 |
0.0109585 |
IL7R/IL2RG/CD3D/RASGRP1/IL1B/CCR7/CD3G |
7 |
| BP |
GO:0045622 |
regulation of T-helper cell differentiation |
5/364 |
43/18903 |
0.0013594 |
0.0136554 |
0.0109803 |
CD80/HLA-DRA/BATF/IRF4/CCL19 |
5 |
| BP |
GO:0044282 |
small molecule catabolic process |
17/364 |
385/18903 |
0.0013649 |
0.0136554 |
0.0109803 |
KMO/KYNU/APOBEC3H/IDO1/TDO2/IL4I1/SDS/ALDH1L1/MAT1A/ACADL/GPT/ACOXL/PLIN5/APOBEC3A/LEP/ADIPOQ/PCK1 |
17 |
| BP |
GO:0070586 |
cell-cell adhesion involved in gastrulation |
3/364 |
12/18903 |
0.0013691 |
0.0136554 |
0.0109803 |
IL10/IL1RN/ADIPOQ |
3 |
| BP |
GO:2000508 |
regulation of dendritic cell chemotaxis |
3/364 |
12/18903 |
0.0013691 |
0.0136554 |
0.0109803 |
SLAMF8/SLAMF1/CCR7 |
3 |
| BP |
GO:0031960 |
response to corticosteroid |
10/364 |
165/18903 |
0.0013834 |
0.0137622 |
0.0110662 |
IL10/IL6/GJB2/PCSK1/SLC12A3/IL1RN/SDC1/ADIPOQ/CSN1S1/PCK1 |
10 |
| BP |
GO:0045860 |
positive regulation of protein kinase activity |
18/364 |
420/18903 |
0.001392 |
0.0138127 |
0.0111068 |
FCGR1A/CKS2/CHI3L1/WNT11/IFNG/ADRA2B/KIF14/RASGRP1/IL1B/CCR7/ANGPT4/STAP1/CCL19/IGF2/ADRA1A/TCL1A/LEP/ADIPOQ |
18 |
| BP |
GO:0019058 |
viral life cycle |
15/364 |
319/18903 |
0.0013969 |
0.0138253 |
0.011117 |
CH25H/CD80/CCR5/LAMP3/CXCR4/SLAMF1/CR1/TOP2A/CCL8/CXCR6/APOBEC3H/CDK1/CR2/FCN1/APOBEC3A |
15 |
| BP |
GO:0002726 |
positive regulation of T cell cytokine production |
4/364 |
26/18903 |
0.0014458 |
0.0142364 |
0.0114475 |
IL6/SLAMF1/XCL1/IL1B |
4 |
| BP |
GO:0050857 |
positive regulation of antigen receptor-mediated signaling pathway |
4/364 |
26/18903 |
0.0014458 |
0.0142364 |
0.0114475 |
TRAT1/CCR7/STAP1/LCK |
4 |
| BP |
GO:0007249 |
I-kappaB kinase/NF-kappaB signaling |
14/364 |
288/18903 |
0.0014638 |
0.0143761 |
0.0115599 |
UBD/TNIP3/TLR8/BIRC3/CLEC4D/RHOH/FASLG/IL1B/PIM2/CCR7/CLEC6A/CCL19/TIFAB/ADIPOQ |
14 |
| BP |
GO:0009063 |
cellular amino acid catabolic process |
8/364 |
113/18903 |
0.001549 |
0.0151372 |
0.0121719 |
KMO/KYNU/IDO1/TDO2/IL4I1/SDS/MAT1A/GPT |
8 |
| BP |
GO:0032613 |
interleukin-10 production |
6/364 |
65/18903 |
0.001553 |
0.0151372 |
0.0121719 |
IL6/TIGIT/IDO1/CD274/XCL1/IRF4 |
6 |
| BP |
GO:0032653 |
regulation of interleukin-10 production |
6/364 |
65/18903 |
0.001553 |
0.0151372 |
0.0121719 |
IL6/TIGIT/IDO1/CD274/XCL1/IRF4 |
6 |
| BP |
GO:0033674 |
positive regulation of kinase activity |
20/364 |
496/18903 |
0.0016026 |
0.015581 |
0.0125287 |
FCGR1A/MAPT/CKS2/CHI3L1/WNT11/IFNG/ADRA2B/KIF14/RASGRP1/IL1B/CCR7/ANGPT4/STAP1/CCL19/IGF2/CD19/ADRA1A/TCL1A/LEP/ADIPOQ |
20 |
| BP |
GO:0002418 |
immune response to tumor cell |
4/364 |
27/18903 |
0.0016718 |
0.0161716 |
0.0130036 |
CRTAM/IL4I1/CD274/TRA |
4 |
| BP |
GO:0032740 |
positive regulation of interleukin-17 production |
4/364 |
27/18903 |
0.0016718 |
0.0161716 |
0.0130036 |
IL6/SLAMF6/OSM/LY9 |
4 |
| BP |
GO:0008037 |
cell recognition |
12/364 |
230/18903 |
0.0017438 |
0.0168261 |
0.0135299 |
FCGR1A/LBP/CXCR4/CRTAM/IGHG1/IGLL5/CCR7/FCN1/CCL19/IGHE/CNTN2/IGHD |
12 |
| BP |
GO:0070486 |
leukocyte aggregation |
3/364 |
13/18903 |
0.0017545 |
0.0168873 |
0.0135791 |
S100A9/IL1B/S100A8 |
3 |
| BP |
GO:1904064 |
positive regulation of cation transmembrane transport |
10/364 |
171/18903 |
0.0018053 |
0.0173325 |
0.0139371 |
CXCL10/IFNG/CCR2/CXCL11/CXCL9/XCL1/WNK2/MS4A1/CD19/JPH2 |
10 |
| BP |
GO:0030888 |
regulation of B cell proliferation |
6/364 |
67/18903 |
0.0018171 |
0.0174028 |
0.0139936 |
IL10/CTLA4/CD38/MZB1/IKZF3/FCRL3 |
6 |
| BP |
GO:0098586 |
cellular response to virus |
8/364 |
116/18903 |
0.0018301 |
0.0174535 |
0.0140344 |
IL6/CXCL10/IFNG/BIRC3/MMP12/IFNE/POU2AF1/CCL19 |
8 |
| BP |
GO:0030534 |
adult behavior |
9/364 |
143/18903 |
0.0018315 |
0.0174535 |
0.0140344 |
LGI4/ATP1A2/CNTN2/KCNJ10/NRXN1/PPP1R1B/LEP/SHANK2/PAX5 |
9 |
| BP |
GO:0002920 |
regulation of humoral immune response |
5/364 |
46/18903 |
0.0018468 |
0.0175128 |
0.014082 |
CXCL13/CR1/IL1B/CCR7/CR2 |
5 |
| BP |
GO:0046006 |
regulation of activated T cell proliferation |
5/364 |
46/18903 |
0.0018468 |
0.0175128 |
0.014082 |
IL2RA/SLAMF1/CRTAM/CD274/IGF2 |
5 |
| BP |
GO:0010996 |
response to auditory stimulus |
4/364 |
28/18903 |
0.0019211 |
0.018128 |
0.0145768 |
CXCL10/ATP1A2/TIFAB/NRXN1 |
4 |
| BP |
GO:0071624 |
positive regulation of granulocyte chemotaxis |
4/364 |
28/18903 |
0.0019211 |
0.018128 |
0.0145768 |
LBP/XCL1/CCR7/CCL19 |
4 |
| BP |
GO:0001774 |
microglial cell activation |
5/364 |
47/18903 |
0.0020345 |
0.019052 |
0.0153197 |
CCL3/IL6/MAPT/IFNG/STAP1 |
5 |
| BP |
GO:0097028 |
dendritic cell differentiation |
5/364 |
47/18903 |
0.0020345 |
0.019052 |
0.0153197 |
BATF/UBD/IRF4/CCR7/CCL19 |
5 |
| BP |
GO:0050730 |
regulation of peptidyl-tyrosine phosphorylation |
13/364 |
266/18903 |
0.0020387 |
0.019052 |
0.0153197 |
FCGR1A/SAMSN1/CD80/IL6/OSM/IFNG/CLEC6A/ANGPT4/STAP1/IGF2/ADRA1A/LEP/ADIPOQ |
13 |
| BP |
GO:0002718 |
regulation of cytokine production involved in immune response |
8/364 |
118/18903 |
0.0020388 |
0.019052 |
0.0153197 |
IL10/IL6/SLAMF1/CCR2/CD96/XCL1/CLNK/IL1B |
8 |
| BP |
GO:0050922 |
negative regulation of chemotaxis |
6/364 |
69/18903 |
0.0021139 |
0.0197058 |
0.0158455 |
SEMA3B/SLAMF8/CXCL13/TNFAIP6/GPR18/STAP1 |
6 |
| BP |
GO:1904427 |
positive regulation of calcium ion transmembrane transport |
7/364 |
93/18903 |
0.0021268 |
0.0197781 |
0.0159036 |
CXCL10/CXCL11/CXCL9/XCL1/MS4A1/CD19/JPH2 |
7 |
| BP |
GO:1901605 |
alpha-amino acid metabolic process |
11/364 |
205/18903 |
0.0021519 |
0.0199631 |
0.0160524 |
SLC39A8/KMO/KYNU/IDO1/TDO2/IL4I1/SDS/MAT1A/GPT/NAT8L/GLYAT |
11 |
| BP |
GO:0032607 |
interferon-alpha production |
4/364 |
29/18903 |
0.002195 |
0.0202658 |
0.0162958 |
IL10/TLR8/MMP12/LILRA4 |
4 |
| BP |
GO:0032647 |
regulation of interferon-alpha production |
4/364 |
29/18903 |
0.002195 |
0.0202658 |
0.0162958 |
IL10/TLR8/MMP12/LILRA4 |
4 |
| BP |
GO:0106106 |
cold-induced thermogenesis |
9/364 |
147/18903 |
0.0022119 |
0.0203241 |
0.0163426 |
CXCR4/CCR2/IRF4/PLAC8/ACADL/CIDEA/LEP/FABP4/ADIPOQ |
9 |
| BP |
GO:0120161 |
regulation of cold-induced thermogenesis |
9/364 |
147/18903 |
0.0022119 |
0.0203241 |
0.0163426 |
CXCR4/CCR2/IRF4/PLAC8/ACADL/CIDEA/LEP/FABP4/ADIPOQ |
9 |
| BP |
GO:0032620 |
interleukin-17 production |
5/364 |
48/18903 |
0.0022358 |
0.0204174 |
0.0164176 |
IL6/SLAMF6/OSM/IFNG/LY9 |
5 |
| BP |
GO:0032660 |
regulation of interleukin-17 production |
5/364 |
48/18903 |
0.0022358 |
0.0204174 |
0.0164176 |
IL6/SLAMF6/OSM/IFNG/LY9 |
5 |
| BP |
GO:0034764 |
positive regulation of transmembrane transport |
12/364 |
237/18903 |
0.002238 |
0.0204174 |
0.0164176 |
CXCL10/IFNG/CCR2/CXCL11/CXCL9/KLF15/XCL1/WNK2/MS4A1/CD19/JPH2/ADIPOQ |
12 |
| BP |
GO:0002367 |
cytokine production involved in immune response |
8/364 |
120/18903 |
0.0022658 |
0.0206228 |
0.0165828 |
IL10/IL6/SLAMF1/CCR2/CD96/XCL1/CLNK/IL1B |
8 |
| BP |
GO:0014823 |
response to activity |
6/364 |
70/18903 |
0.0022753 |
0.0206604 |
0.016613 |
IL10/CXCR4/IL6/CDK1/LEP/ADIPOQ |
6 |
| BP |
GO:0016042 |
lipid catabolic process |
15/364 |
336/18903 |
0.0023111 |
0.0209358 |
0.0168345 |
PLA2G2D/SPP1/PLA2G7/IL1B/SMPDL3B/ACADL/PLIN1/LIPE/ACOXL/PLIN5/LGALS12/CIDEA/LEP/ADIPOQ/PCK1 |
15 |
| BP |
GO:0051607 |
defense response to virus |
14/364 |
304/18903 |
0.0024127 |
0.0218046 |
0.0175331 |
AIM2/IL6/CXCL10/IFNG/TLR8/BIRC3/APOBEC3H/CXCL9/MMP12/IL1B/ZBP1/RNASE2/IFNE/APOBEC3A |
14 |
| BP |
GO:0001659 |
temperature homeostasis |
10/364 |
178/18903 |
0.0024231 |
0.0218473 |
0.0175675 |
CXCR4/CCR2/IL1B/IRF4/PLAC8/ACADL/CIDEA/LEP/FABP4/ADIPOQ |
10 |
| BP |
GO:0051057 |
positive regulation of small GTPase mediated signal transduction |
6/364 |
71/18903 |
0.0024459 |
0.0219985 |
0.017689 |
GPR65/TGM2/P2RY10/GPR174/RASGRP1/GPR18 |
6 |
| BP |
GO:0050798 |
activated T cell proliferation |
5/364 |
49/18903 |
0.0024513 |
0.0219985 |
0.017689 |
IL2RA/SLAMF1/CRTAM/CD274/IGF2 |
5 |
| BP |
GO:0140546 |
defense response to symbiont |
14/364 |
305/18903 |
0.0024858 |
0.0221818 |
0.0178364 |
AIM2/IL6/CXCL10/IFNG/TLR8/BIRC3/APOBEC3H/CXCL9/MMP12/IL1B/ZBP1/RNASE2/IFNE/APOBEC3A |
14 |
| BP |
GO:0043032 |
positive regulation of macrophage activation |
4/364 |
30/18903 |
0.0024947 |
0.0221818 |
0.0178364 |
LBP/CCL3/IL10/STAP1 |
4 |
| BP |
GO:0060292 |
long-term synaptic depression |
4/364 |
30/18903 |
0.0024947 |
0.0221818 |
0.0178364 |
MAPT/CD38/GRIA1/SHANK2 |
4 |
| BP |
GO:0070498 |
interleukin-1-mediated signaling pathway |
4/364 |
30/18903 |
0.0024947 |
0.0221818 |
0.0178364 |
IL6/IL1B/ZBP1/IL1RN |
4 |
| BP |
GO:0002275 |
myeloid cell activation involved in immune response |
7/364 |
96/18903 |
0.0025482 |
0.0226048 |
0.0181766 |
LBP/CCL3/SLAMF1/IFNG/CCR2/RASGRP1/CLNK |
7 |
| BP |
GO:0046718 |
viral entry into host cell |
9/364 |
151/18903 |
0.0026527 |
0.0233642 |
0.0187872 |
CH25H/CD80/CCR5/CXCR4/SLAMF1/CR1/CDK1/CR2/FCN1 |
9 |
| BP |
GO:0002269 |
leukocyte activation involved in inflammatory response |
5/364 |
50/18903 |
0.0026814 |
0.0233642 |
0.0187872 |
CCL3/IL6/MAPT/IFNG/STAP1 |
5 |
| BP |
GO:1990573 |
potassium ion import across plasma membrane |
5/364 |
50/18903 |
0.0026814 |
0.0233642 |
0.0187872 |
ATP1A2/WNK2/SLC12A3/KCNJ10/KCNJ6 |
5 |
| BP |
GO:0006576 |
cellular biogenic amine metabolic process |
7/364 |
97/18903 |
0.002702 |
0.0233642 |
0.0187872 |
KMO/KYNU/IDO1/TDO2/IL4I1/MOXD1/PNMT |
7 |
| BP |
GO:0001768 |
establishment of T cell polarity |
3/364 |
15/18903 |
0.0027127 |
0.0233642 |
0.0187872 |
CRTAM/CCR7/CCL19 |
3 |
| BP |
GO:0001787 |
natural killer cell proliferation |
3/364 |
15/18903 |
0.0027127 |
0.0233642 |
0.0187872 |
FCGR3A/SLAMF1/LEP |
3 |
| BP |
GO:0002468 |
dendritic cell antigen processing and presentation |
3/364 |
15/18903 |
0.0027127 |
0.0233642 |
0.0187872 |
HLA-DRA/CCR7/CCL19 |
3 |
| BP |
GO:0002517 |
T cell tolerance induction |
3/364 |
15/18903 |
0.0027127 |
0.0233642 |
0.0187872 |
IL2RA/ICOS/IDO1 |
3 |
| BP |
GO:0002864 |
regulation of acute inflammatory response to antigenic stimulus |
3/364 |
15/18903 |
0.0027127 |
0.0233642 |
0.0187872 |
FCGR1A/PLA2G2D/CCR7 |
3 |
| BP |
GO:0032725 |
positive regulation of granulocyte macrophage colony-stimulating factor production |
3/364 |
15/18903 |
0.0027127 |
0.0233642 |
0.0187872 |
CD80/RASGRP1/IL1B |
3 |
| BP |
GO:0034116 |
positive regulation of heterotypic cell-cell adhesion |
3/364 |
15/18903 |
0.0027127 |
0.0233642 |
0.0187872 |
IL10/IL1B/LCK |
3 |
| BP |
GO:0045579 |
positive regulation of B cell differentiation |
3/364 |
15/18903 |
0.0027127 |
0.0233642 |
0.0187872 |
IL10/IL2RG/CD27 |
3 |
| BP |
GO:0070234 |
positive regulation of T cell apoptotic process |
3/364 |
15/18903 |
0.0027127 |
0.0233642 |
0.0187872 |
IDO1/CD274/PDCD1 |
3 |
| BP |
GO:0050804 |
modulation of chemical synaptic transmission |
18/364 |
448/18903 |
0.0028031 |
0.0240895 |
0.0193704 |
KMO/MAPT/CLSTN2/CD38/ATP1A2/CCR2/GRIA1/IL1B/GRIK5/CNTN2/ADRA1A/KCNJ10/GRIK3/CNR2/DCC/NRXN1/SHANK2/ADIPOQ |
18 |
| BP |
GO:0002313 |
mature B cell differentiation involved in immune response |
4/364 |
31/18903 |
0.0028214 |
0.0241923 |
0.0194531 |
IL10/IL6/CR1/POU2AF1 |
4 |
| BP |
GO:0099177 |
regulation of trans-synaptic signaling |
18/364 |
449/18903 |
0.0028701 |
0.0245553 |
0.019745 |
KMO/MAPT/CLSTN2/CD38/ATP1A2/CCR2/GRIA1/IL1B/GRIK5/CNTN2/ADRA1A/KCNJ10/GRIK3/CNR2/DCC/NRXN1/SHANK2/ADIPOQ |
18 |
| BP |
GO:0050873 |
brown fat cell differentiation |
5/364 |
51/18903 |
0.0029267 |
0.024984 |
0.0200897 |
SLC2A4/PLAC8/LEP/FABP4/ADIPOQ |
5 |
| BP |
GO:0032755 |
positive regulation of interleukin-6 production |
7/364 |
99/18903 |
0.003031 |
0.0258172 |
0.0207596 |
LBP/IL6/IFNG/TLR8/IL1B/POU2AF1/LEP |
7 |
| BP |
GO:0098659 |
inorganic cation import across plasma membrane |
8/364 |
126/18903 |
0.0030677 |
0.0260144 |
0.0209182 |
SLC39A8/IFNG/ATP1A2/WNK2/MS4A1/SLC12A3/KCNJ10/KCNJ6 |
8 |
| BP |
GO:0099587 |
inorganic ion import across plasma membrane |
8/364 |
126/18903 |
0.0030677 |
0.0260144 |
0.0209182 |
SLC39A8/IFNG/ATP1A2/WNK2/MS4A1/SLC12A3/KCNJ10/KCNJ6 |
8 |
| BP |
GO:0050728 |
negative regulation of inflammatory response |
10/364 |
184/18903 |
0.0030784 |
0.0260478 |
0.0209451 |
SLAMF8/IL10/IL2RA/SIGLEC10/PBK/TNFAIP6/SMPDL3B/FPR2/CNR2/ADIPOQ |
10 |
| BP |
GO:0002717 |
positive regulation of natural killer cell mediated immunity |
4/364 |
32/18903 |
0.0031761 |
0.0267574 |
0.0215157 |
SLAMF6/CRTAM/RASGRP1/CLNK |
4 |
| BP |
GO:0051482 |
positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway |
4/364 |
32/18903 |
0.0031761 |
0.0267574 |
0.0215157 |
GPR65/P2RY10/GPR174/GPR18 |
4 |
| BP |
GO:0001767 |
establishment of lymphocyte polarity |
3/364 |
16/18903 |
0.0032914 |
0.0276076 |
0.0221993 |
CRTAM/CCR7/CCL19 |
3 |
| BP |
GO:0050862 |
positive regulation of T cell receptor signaling pathway |
3/364 |
16/18903 |
0.0032914 |
0.0276076 |
0.0221993 |
TRAT1/CCR7/LCK |
3 |
| BP |
GO:0034767 |
positive regulation of ion transmembrane transport |
10/364 |
186/18903 |
0.0033257 |
0.0278351 |
0.0223822 |
CXCL10/IFNG/CCR2/CXCL11/CXCL9/XCL1/WNK2/MS4A1/CD19/JPH2 |
10 |
| BP |
GO:0002637 |
regulation of immunoglobulin production |
6/364 |
76/18903 |
0.0034465 |
0.0287238 |
0.0230969 |
IL10/IL6/CR1/MZB1/XCL1/FCRL3 |
6 |
| BP |
GO:0016032 |
viral process |
17/364 |
421/18903 |
0.003454 |
0.0287238 |
0.0230969 |
CCL4/CH25H/CD80/CCL3/CCR5/LAMP3/CXCR4/SLAMF1/CR1/TOP2A/CCL8/CXCR6/APOBEC3H/CDK1/CR2/FCN1/APOBEC3A |
17 |
| BP |
GO:0042180 |
cellular ketone metabolic process |
11/364 |
218/18903 |
0.0034543 |
0.0287238 |
0.0230969 |
KMO/KYNU/IDO1/TDO2/IL1B/BMP5/ACADL/GPD1/PLIN5/MLXIPL/ADIPOQ |
11 |
| BP |
GO:0002828 |
regulation of type 2 immune response |
4/364 |
33/18903 |
0.0035601 |
0.0295399 |
0.023753 |
IL6/IDO1/CCR2/XCL1 |
4 |
| BP |
GO:0044409 |
entry into host |
9/364 |
158/18903 |
0.0035891 |
0.0297163 |
0.0238949 |
CH25H/CD80/CCR5/CXCR4/SLAMF1/CR1/CDK1/CR2/FCN1 |
9 |
| BP |
GO:0043123 |
positive regulation of I-kappaB kinase/NF-kappaB signaling |
10/364 |
189/18903 |
0.0037262 |
0.030785 |
0.0247543 |
UBD/BIRC3/CLEC4D/FASLG/IL1B/PIM2/CCR7/CLEC6A/CCL19/ADIPOQ |
10 |
| BP |
GO:0014009 |
glial cell proliferation |
5/364 |
54/18903 |
0.0037599 |
0.0309966 |
0.0249244 |
IL6/LGI4/IL1B/NTN1/SOX10 |
5 |
| BP |
GO:0006910 |
phagocytosis, recognition |
7/364 |
103/18903 |
0.0037801 |
0.0310966 |
0.0250048 |
FCGR1A/LBP/IGHG1/IGLL5/FCN1/IGHE/IGHD |
7 |
| BP |
GO:1990845 |
adaptive thermogenesis |
9/364 |
160/18903 |
0.0038994 |
0.03201 |
0.0257393 |
CXCR4/CCR2/IRF4/PLAC8/ACADL/CIDEA/LEP/FABP4/ADIPOQ |
9 |
| BP |
GO:0032743 |
positive regulation of interleukin-2 production |
4/364 |
34/18903 |
0.0039745 |
0.0324188 |
0.026068 |
CD80/CCR2/IL1B/IRF4 |
4 |
| BP |
GO:0035025 |
positive regulation of Rho protein signal transduction |
4/364 |
34/18903 |
0.0039745 |
0.0324188 |
0.026068 |
GPR65/P2RY10/GPR174/GPR18 |
4 |
| BP |
GO:1902624 |
positive regulation of neutrophil migration |
4/364 |
34/18903 |
0.0039745 |
0.0324188 |
0.026068 |
LBP/XCL1/CCR7/CCL19 |
4 |
| BP |
GO:0043122 |
regulation of I-kappaB kinase/NF-kappaB signaling |
12/364 |
255/18903 |
0.0040501 |
0.0329656 |
0.0265077 |
UBD/TNIP3/BIRC3/CLEC4D/RHOH/FASLG/IL1B/PIM2/CCR7/CLEC6A/CCL19/ADIPOQ |
12 |
| BP |
GO:1904645 |
response to amyloid-beta |
5/364 |
55/18903 |
0.0040718 |
0.0330728 |
0.0265939 |
MMP3/MMP13/ITGA4/MMP12/FPR2 |
5 |
| BP |
GO:0007193 |
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway |
6/364 |
79/18903 |
0.004177 |
0.0338559 |
0.0272235 |
RGS1/PALM/ADCY5/FPR2/GRIK3/NPY1R |
6 |
| BP |
GO:0002719 |
negative regulation of cytokine production involved in immune response |
4/364 |
35/18903 |
0.0044202 |
0.035742 |
0.0287401 |
IL10/SLAMF1/CD96/XCL1 |
4 |
| BP |
GO:0006958 |
complement activation, classical pathway |
7/364 |
106/18903 |
0.0044283 |
0.035742 |
0.0287401 |
CR1/IGHG1/IGLL5/CR2/IGHE/C6/IGHD |
7 |
| BP |
GO:0002830 |
positive regulation of type 2 immune response |
3/364 |
18/18903 |
0.0046613 |
0.0371608 |
0.0298811 |
IL6/IDO1/XCL1 |
3 |
| BP |
GO:0016264 |
gap junction assembly |
3/364 |
18/18903 |
0.0046613 |
0.0371608 |
0.0298811 |
GJB2/IL1B/GJB6 |
3 |
| BP |
GO:0030730 |
sequestering of triglyceride |
3/364 |
18/18903 |
0.0046613 |
0.0371608 |
0.0298811 |
IL1B/PLIN5/CIDEA |
3 |
| BP |
GO:0032604 |
granulocyte macrophage colony-stimulating factor production |
3/364 |
18/18903 |
0.0046613 |
0.0371608 |
0.0298811 |
CD80/RASGRP1/IL1B |
3 |
| BP |
GO:0032645 |
regulation of granulocyte macrophage colony-stimulating factor production |
3/364 |
18/18903 |
0.0046613 |
0.0371608 |
0.0298811 |
CD80/RASGRP1/IL1B |
3 |
| BP |
GO:0062207 |
regulation of pattern recognition receptor signaling pathway |
7/364 |
107/18903 |
0.004662 |
0.0371608 |
0.0298811 |
LBP/CD300LF/BIRC3/FCRL3/IRF4/LILRA4/SMPDL3B |
7 |
| BP |
GO:0032768 |
regulation of monooxygenase activity |
5/364 |
57/18903 |
0.0047505 |
0.0377101 |
0.0303228 |
IFNG/IL1B/S100A1/CNR2/LEP |
5 |
| BP |
GO:0061756 |
leukocyte adhesion to vascular endothelial cell |
5/364 |
57/18903 |
0.0047505 |
0.0377101 |
0.0303228 |
SLC39A8/IL6/SELE/ITGA4/LEP |
5 |
| BP |
GO:0006026 |
aminoglycan catabolic process |
4/364 |
36/18903 |
0.0048984 |
0.0385384 |
0.0309887 |
CHI3L2/HMMR/CHI3L1/HPSE2 |
4 |
| BP |
GO:0050869 |
negative regulation of B cell activation |
4/364 |
36/18903 |
0.0048984 |
0.0385384 |
0.0309887 |
SAMSN1/IL10/CTLA4/CR1 |
4 |
| BP |
GO:1903514 |
release of sequestered calcium ion into cytosol by endoplasmic reticulum |
4/364 |
36/18903 |
0.0048984 |
0.0385384 |
0.0309887 |
CCL3/CCR5/ATP1A2/FASLG |
4 |
| BP |
GO:0044106 |
cellular amine metabolic process |
7/364 |
108/18903 |
0.0049049 |
0.0385384 |
0.0309887 |
KMO/KYNU/IDO1/TDO2/IL4I1/MOXD1/PNMT |
7 |
| BP |
GO:0051341 |
regulation of oxidoreductase activity |
7/364 |
108/18903 |
0.0049049 |
0.0385384 |
0.0309887 |
SLAMF8/IFNG/GZMA/IL1B/S100A1/CNR2/LEP |
7 |
| BP |
GO:0001959 |
regulation of cytokine-mediated signaling pathway |
9/364 |
167/18903 |
0.0051538 |
0.0404115 |
0.0324949 |
CXCR4/IL6/CD300LF/NLRP2/MMP12/ZBP1/STAP1/IL1RN/ADIPOQ |
9 |
| BP |
GO:0006094 |
gluconeogenesis |
6/364 |
83/18903 |
0.0053214 |
0.0416412 |
0.0334837 |
SDS/GPT/GPD1/LEP/ADIPOQ/PCK1 |
6 |
| BP |
GO:0070229 |
negative regulation of lymphocyte apoptotic process |
4/364 |
37/18903 |
0.0054102 |
0.0422501 |
0.0339734 |
IL7R/IDO1/CD27/PDCD1 |
4 |
| BP |
GO:0045091 |
regulation of single stranded viral RNA replication via double stranded DNA intermediate |
3/364 |
19/18903 |
0.0054572 |
0.0424447 |
0.0341298 |
TOP2A/APOBEC3H/APOBEC3A |
3 |
| BP |
GO:2001185 |
regulation of CD8-positive, alpha-beta T cell activation |
3/364 |
19/18903 |
0.0054572 |
0.0424447 |
0.0341298 |
CRTAM/CD274/XCL1 |
3 |
| BP |
GO:1905517 |
macrophage migration |
5/364 |
60/18903 |
0.0059136 |
0.0459023 |
0.0369101 |
CCL3/SLAMF8/SLAMF1/CCR2/STAP1 |
5 |
| BP |
GO:0051924 |
regulation of calcium ion transport |
12/364 |
268/18903 |
0.0059784 |
0.0463119 |
0.0372394 |
CCL4/CCL3/CXCR4/CXCL10/ATP1A2/CXCL11/CXCL9/XCL1/FCRL3/MS4A1/CD19/JPH2 |
12 |
| BP |
GO:2000116 |
regulation of cysteine-type endopeptidase activity |
11/364 |
235/18903 |
0.0060376 |
0.0466761 |
0.0375323 |
LAMP3/AIM2/MAPT/CRYAB/BIRC3/S100A9/NLRP2/FASLG/S100A8/LCK/CD27 |
11 |
| BP |
GO:0042552 |
myelination |
8/364 |
142/18903 |
0.0062981 |
0.0481602 |
0.0387257 |
MYOC/CXCR4/LGI4/KIF14/RXRG/SOX10/CNTN2/KCNJ10 |
8 |
| BP |
GO:0051384 |
response to glucocorticoid |
8/364 |
142/18903 |
0.0062981 |
0.0481602 |
0.0387257 |
IL10/IL6/GJB2/PCSK1/IL1RN/SDC1/ADIPOQ/PCK1 |
8 |
| BP |
GO:0019319 |
hexose biosynthetic process |
6/364 |
86/18903 |
0.0063192 |
0.0481602 |
0.0387257 |
SDS/GPT/GPD1/LEP/ADIPOQ/PCK1 |
6 |
| BP |
GO:0002577 |
regulation of antigen processing and presentation |
3/364 |
20/18903 |
0.0063296 |
0.0481602 |
0.0387257 |
HLA-DOB/CCR7/CCL19 |
3 |
| BP |
GO:0002837 |
regulation of immune response to tumor cell |
3/364 |
20/18903 |
0.0063296 |
0.0481602 |
0.0387257 |
CRTAM/IL4I1/CD274 |
3 |
| BP |
GO:0039692 |
single stranded viral RNA replication via double stranded DNA intermediate |
3/364 |
20/18903 |
0.0063296 |
0.0481602 |
0.0387257 |
TOP2A/APOBEC3H/APOBEC3A |
3 |
| BP |
GO:0043011 |
myeloid dendritic cell differentiation |
3/364 |
20/18903 |
0.0063296 |
0.0481602 |
0.0387257 |
BATF/UBD/IRF4 |
3 |
| BP |
GO:1903978 |
regulation of microglial cell activation |
3/364 |
20/18903 |
0.0063296 |
0.0481602 |
0.0387257 |
CCL3/IL6/STAP1 |
3 |
| BP |
GO:0009595 |
detection of biotic stimulus |
4/364 |
39/18903 |
0.0065383 |
0.0493518 |
0.0396838 |
LBP/CRTAM/TRA/CLEC6A |
4 |
| BP |
GO:0032570 |
response to progesterone |
4/364 |
39/18903 |
0.0065383 |
0.0493518 |
0.0396838 |
GJB2/CD38/SOX10/CSN1S1 |
4 |
| BP |
GO:0060251 |
regulation of glial cell proliferation |
4/364 |
39/18903 |
0.0065383 |
0.0493518 |
0.0396838 |
IL6/IL1B/NTN1/SOX10 |
4 |
| BP |
GO:0043281 |
regulation of cysteine-type endopeptidase activity involved in apoptotic process |
10/364 |
205/18903 |
0.0065503 |
0.0493518 |
0.0396838 |
LAMP3/MAPT/CRYAB/BIRC3/S100A9/NLRP2/FASLG/S100A8/LCK/CD27 |
10 |
| BP |
GO:1901654 |
response to ketone |
10/364 |
205/18903 |
0.0065503 |
0.0493518 |
0.0396838 |
GJB2/SPP1/CD38/ADCY5/CCR7/SLC12A3/CCL19/SOX10/CSN1S1/PCK1 |
10 |
| CC |
GO:0009897 |
external side of plasma membrane |
54/369 |
462/19869 |
1.23E-27 |
4.52E-25 |
4.13E-25 |
FCGR1A/CD80/CCR5/IL21R/FCGR3A/CXCR4/SLAMF6/SLAMF7/SELE/IL2RA/SLAMF1/IL7R/CD69/CXCL10/ITGA4/CTLA4/CD2/CNTFR/TLR8/CCR4/IL2RG/CD48/CXCR6/CD3D/CLEC4D/CCR2/IGHG1/CXCL9/CD274/LY9/FASLG/ITGA11/IGLL5/CLEC4C/SLC2A4/CD79A/KLRC1/CCR7/CLEC6A/CD3G/MS4A1/CLEC4E/CD27/FCN1/F10/CLEC17A/TRGC2/IGHE/CD19/PDCD1/SDC1/IGHD/SCUBE1/AZGP1 |
54 |
| CC |
GO:0070820 |
tertiary granule |
13/369 |
164/19869 |
1.24E-05 |
0.0021705 |
0.0019851 |
GPR84/CXCL1/LYZ/CR1/FPR1/TNFAIP6/CLEC4D/LILRA3/CLEC4C/FCAR/OLR1/FPR2/CLEC12A |
13 |
| CC |
GO:0001772 |
immunological synapse |
7/369 |
45/19869 |
1.78E-05 |
0.0021705 |
0.0019851 |
HLA-DRA/CRTAM/GZMA/IL4I1/RHOH/GZMB/LCK |
7 |
| CC |
GO:0042105 |
alpha-beta T cell receptor complex |
4/369 |
11/19869 |
3.48E-05 |
0.0031875 |
0.0029152 |
CD3D/TRA/CD3G/TRAC |
4 |
| CC |
GO:0070821 |
tertiary granule membrane |
8/369 |
73/19869 |
6.16E-05 |
0.0045078 |
0.0041227 |
GPR84/CLEC4D/LILRA3/CLEC4C/FCAR/OLR1/FPR2/CLEC12A |
8 |
| CC |
GO:0101003 |
ficolin-1-rich granule membrane |
7/369 |
61/19869 |
0.0001326 |
0.0065486 |
0.0059892 |
CR1/FPR1/CLEC4D/LILRA3/CLEC4C/FCAR/FPR2 |
7 |
| CC |
GO:0045121 |
membrane raft |
17/369 |
326/19869 |
0.000138 |
0.0065486 |
0.0059892 |
MAPT/SELE/CD2/CR1/CD48/ATP1A2/BIRC3/FASLG/KCNA3/SLC2A4/CD79A/MS4A1/LCK/OLR1/CD19/ADRA1A/LIPE |
17 |
| CC |
GO:0098857 |
membrane microdomain |
17/369 |
327/19869 |
0.0001431 |
0.0065486 |
0.0059892 |
MAPT/SELE/CD2/CR1/CD48/ATP1A2/BIRC3/FASLG/KCNA3/SLC2A4/CD79A/MS4A1/LCK/OLR1/CD19/ADRA1A/LIPE |
17 |
| CC |
GO:0062023 |
collagen-containing extracellular matrix |
20/369 |
433/19869 |
0.0001886 |
0.0076689 |
0.0070139 |
ADAMDEC1/LTBP4/SEMA3B/MYOC/TNXB/VWA2/TGM2/S100A9/COL6A5/EMILIN3/NTN1/GDF10/CILP/S100A8/ANGPT4/FCN1/TMEFF2/ADIPOQ/AZGP1/AMTN |
20 |
| CC |
GO:0042613 |
MHC class II protein complex |
4/369 |
17/19869 |
0.00023 |
0.0084178 |
0.0076988 |
HLA-DQA1/HLA-DRA/HLA-DOB/HLA-DQB2 |
4 |
| CC |
GO:0045334 |
clathrin-coated endocytic vesicle |
8/369 |
90/19869 |
0.0002702 |
0.0089912 |
0.0082232 |
FCGR1A/HLA-DQA1/HLA-DRA/IL7R/CTLA4/CD3D/CD3G/HLA-DQB2 |
8 |
| CC |
GO:0030669 |
clathrin-coated endocytic vesicle membrane |
7/369 |
72/19869 |
0.0003761 |
0.0114718 |
0.0104919 |
FCGR1A/HLA-DQA1/HLA-DRA/IL7R/CD3D/CD3G/HLA-DQB2 |
7 |
| CC |
GO:0005811 |
lipid droplet |
8/369 |
102/19869 |
0.0006308 |
0.0177592 |
0.0162423 |
PLIN4/PLIN1/LIPE/AQP7/PLIN5/CIDEA/CIDEC/FABP4 |
8 |
| CC |
GO:0042581 |
specific granule |
10/369 |
160/19869 |
0.0008366 |
0.0218713 |
0.0200031 |
GPR84/CXCL1/LYZ/CHI3L1/CLEC4D/LILRA3/FCAR/OLR1/FPR2/CLEC12A |
10 |
| CC |
GO:0098802 |
plasma membrane signaling receptor complex |
15/369 |
319/19869 |
0.0009807 |
0.0239286 |
0.0218847 |
IL6/IL2RA/ITGA4/CNTFR/CD3D/TRAT1/GRIA1/ITGA11/TRA/CD79A/CD3G/GRIK5/TRAC/TRGC2/GRIK3 |
15 |
| CC |
GO:0042611 |
MHC protein complex |
4/369 |
25/19869 |
0.0010872 |
0.0248687 |
0.0227444 |
HLA-DQA1/HLA-DRA/HLA-DOB/HLA-DQB2 |
4 |
| CC |
GO:0035579 |
specific granule membrane |
7/369 |
91/19869 |
0.0015311 |
0.0329643 |
0.0301485 |
GPR84/CLEC4D/LILRA3/FCAR/OLR1/FPR2/CLEC12A |
7 |
| MF |
GO:0008009 |
chemokine activity |
18/357 |
49/18432 |
6.43E-19 |
3.60E-16 |
3.20E-16 |
CXCL6/CCL4/CCL18/CXCL1/CCL3/CXCL13/CXCL3/CCL7/CXCL10/CCL8/CXCL2/CXCL11/CXCL9/XCL2/XCL1/CCL13/CCL19/CCL20 |
18 |
| MF |
GO:0005125 |
cytokine activity |
32/357 |
237/18432 |
4.50E-18 |
1.26E-15 |
1.12E-15 |
CXCL6/CCL4/CCL18/CXCL1/CCL3/CXCL13/CXCL3/IL10/IL6/WNT11/CCL7/CXCL10/OSM/IFNG/SPP1/CCL8/CXCL2/CXCL11/CXCL9/XCL2/XCL1/FASLG/IL1B/WNT10A/GDF10/CCL13/IFNE/CCL19/BMP5/IL1RN/CCL20/ADIPOQ |
32 |
| MF |
GO:0042379 |
chemokine receptor binding |
19/357 |
71/18432 |
6.13E-17 |
1.14E-14 |
1.02E-14 |
CXCL6/CCL4/CCL18/CXCL1/CCL3/CXCL13/CXCL3/CCL7/CXCL10/CCL8/CXCL2/CCR2/CXCL11/CXCL9/XCL2/XCL1/CCL13/CCL19/CCL20 |
19 |
| MF |
GO:0140375 |
immune receptor activity |
24/357 |
148/18432 |
1.11E-15 |
1.56E-13 |
1.38E-13 |
FCGR1A/HLA-DQA1/HLA-DRA/CCR5/IL21R/FCGR3A/CXCR4/IL2RA/IL7R/CNTFR/CR1/FPR1/CCR4/IL2RG/CXCR6/HLA-DOB/CCR2/LILRA3/KLRC1/CCR7/CR2/LILRA4/FPR2/HLA-DQB2 |
24 |
| MF |
GO:0005126 |
cytokine receptor binding |
29/357 |
273/18432 |
1.03E-13 |
1.15E-11 |
1.02E-11 |
CXCL6/CCL4/CCL18/CXCL1/CCL3/CXCL13/CXCL3/IL10/IL6/CD300LF/CCL7/CXCL10/OSM/IFNG/CCL8/CXCL2/CCR2/CXCL11/CXCL9/XCL2/XCL1/FASLG/IL1B/CCL13/STAP1/IFNE/CCL19/IL1RN/CCL20 |
29 |
| MF |
GO:0030546 |
signaling receptor activator activity |
38/357 |
498/18432 |
5.63E-13 |
5.25E-11 |
4.67E-11 |
CXCL6/CCL4/CCL18/CXCL1/SEMA3B/CCL3/CXCL13/CXCL3/IL10/IL6/WNT11/CCL7/CXCL10/OSM/IFNG/SPP1/CCL8/CXCL2/CXCL11/CXCL9/XCL2/XCL1/FASLG/IL1B/WNT10A/GDF10/PNOC/INS-IGF2/CCL13/ANGPT4/IFNE/CCL19/BMP5/IGF2/IL1RN/CCL20/LEP/ADIPOQ |
38 |
| MF |
GO:0048018 |
receptor ligand activity |
37/357 |
491/18432 |
1.69E-12 |
1.35E-10 |
1.20E-10 |
CXCL6/CCL4/CCL18/CXCL1/SEMA3B/CCL3/CXCL13/CXCL3/IL10/IL6/WNT11/CCL7/CXCL10/OSM/IFNG/SPP1/CCL8/CXCL2/CXCL11/CXCL9/XCL2/XCL1/FASLG/IL1B/WNT10A/GDF10/PNOC/INS-IGF2/CCL13/IFNE/CCL19/BMP5/IGF2/IL1RN/CCL20/LEP/ADIPOQ |
37 |
| MF |
GO:0048020 |
CCR chemokine receptor binding |
12/357 |
47/18432 |
6.59E-11 |
4.61E-09 |
4.10E-09 |
CCL4/CCL18/CCL3/CXCL13/CCL7/CCL8/CCR2/XCL2/XCL1/CCL13/CCL19/CCL20 |
12 |
| MF |
GO:0001664 |
G protein-coupled receptor binding |
26/357 |
289/18432 |
8.70E-11 |
5.41E-09 |
4.81E-09 |
CXCL6/CCL4/CCL18/CXCL1/CCL3/MYOC/CXCL13/CXCL3/WNT11/CCL7/CXCL10/FPR1/CCL8/CXCL2/PALM/CCR2/CXCL11/CXCL9/XCL2/XCL1/WNT10A/PNOC/CCL13/FCN1/CCL19/CCL20 |
26 |
| MF |
GO:0045236 |
CXCR chemokine receptor binding |
8/357 |
18/18432 |
6.77E-10 |
3.79E-08 |
3.37E-08 |
CXCL6/CXCL1/CXCL13/CXCL3/CXCL10/CXCL2/CXCL11/CXCL9 |
8 |
| MF |
GO:0030246 |
carbohydrate binding |
19/357 |
275/18432 |
1.89E-06 |
9.64E-05 |
8.57E-05 |
HLA-DRA/CHI3L2/SELE/CHI3L1/CD69/SIGLEC10/KLRB1/CLEC4D/CLEC4C/KLRC1/CLEC6A/CLEC4E/FCN1/CLEC17A/LGALS2/OLR1/CNTN2/CLEC12A/LGALS12 |
19 |
| MF |
GO:0019956 |
chemokine binding |
7/357 |
33/18432 |
2.67E-06 |
0.0001195 |
0.0001062 |
CCR5/CXCR4/ITGA4/CCR4/CXCR6/CCR2/CCR7 |
7 |
| MF |
GO:0004896 |
cytokine receptor activity |
11/357 |
97/18432 |
2.77E-06 |
0.0001195 |
0.0001062 |
CCR5/IL21R/CXCR4/IL2RA/IL7R/CNTFR/CCR4/IL2RG/CXCR6/CCR2/CCR7 |
11 |
| MF |
GO:0016493 |
C-C chemokine receptor activity |
6/357 |
23/18432 |
3.87E-06 |
0.0001547 |
0.0001375 |
CCR5/CXCR4/CCR4/CXCR6/CCR2/CCR7 |
6 |
| MF |
GO:0019957 |
C-C chemokine binding |
6/357 |
24/18432 |
5.07E-06 |
0.0001894 |
0.0001684 |
CCR5/CXCR4/CCR4/CXCR6/CCR2/CCR7 |
6 |
| MF |
GO:0001637 |
G protein-coupled chemoattractant receptor activity |
6/357 |
26/18432 |
8.40E-06 |
0.0002766 |
0.000246 |
CCR5/CXCR4/CCR4/CXCR6/CCR2/CCR7 |
6 |
| MF |
GO:0004950 |
chemokine receptor activity |
6/357 |
26/18432 |
8.40E-06 |
0.0002766 |
0.000246 |
CCR5/CXCR4/CCR4/CXCR6/CCR2/CCR7 |
6 |
| MF |
GO:0019955 |
cytokine binding |
12/357 |
144/18432 |
2.43E-05 |
0.0007559 |
0.0006721 |
LTBP4/CCR5/CXCR4/IL2RA/ITGA4/CNTFR/CCR4/IL2RG/CXCR6/CCR2/CCR7/IL1RN |
12 |
| MF |
GO:0032395 |
MHC class II receptor activity |
4/357 |
10/18432 |
2.65E-05 |
0.000781 |
0.0006944 |
HLA-DQA1/HLA-DRA/HLA-DOB/HLA-DQB2 |
4 |
| MF |
GO:0015026 |
coreceptor activity |
7/357 |
48/18432 |
3.58E-05 |
0.0010037 |
0.0008924 |
CD80/CCR5/CXCR4/ITGA4/CXCR6/LILRA4/FCRL1 |
7 |
| MF |
GO:0023023 |
MHC protein complex binding |
6/357 |
36/18432 |
6.03E-05 |
0.0015418 |
0.0013708 |
HLA-DQA1/HLA-DRA/HLA-DOB/KLRC1/MS4A1/HLA-DQB2 |
6 |
| MF |
GO:0004875 |
complement receptor activity |
4/357 |
12/18432 |
6.06E-05 |
0.0015418 |
0.0013708 |
CR1/FPR1/CR2/FPR2 |
4 |
| MF |
GO:0023026 |
MHC class II protein complex binding |
5/357 |
27/18432 |
0.0001506 |
0.0035147 |
0.0031249 |
HLA-DQA1/HLA-DRA/HLA-DOB/MS4A1/HLA-DQB2 |
5 |
| MF |
GO:0038187 |
pattern recognition receptor activity |
5/357 |
27/18432 |
0.0001506 |
0.0035147 |
0.0031249 |
TLR8/CLEC4D/CLEC6A/CLEC4E/FCN1 |
5 |
| MF |
GO:0003823 |
antigen binding |
11/357 |
171/18432 |
0.0005163 |
0.0115652 |
0.0102826 |
HLA-DQA1/HLA-DRA/SLAMF1/IL7R/ITGA4/CD48/IGHG1/IGLL5/FCN1/IGHE/IGHD |
11 |
| MF |
GO:0008528 |
G protein-coupled peptide receptor activity |
10/357 |
147/18432 |
0.0005953 |
0.0128212 |
0.0113993 |
GPR84/CCR5/CXCR4/FPR1/CCR4/CXCR6/CCR2/CCR7/FPR2/NPY1R |
10 |
| MF |
GO:0001618 |
virus receptor activity |
7/357 |
77/18432 |
0.0007249 |
0.0141503 |
0.012581 |
CD80/CCR5/CXCR4/SLAMF1/CR1/CDK1/CR2 |
7 |
| MF |
GO:0033691 |
sialic acid binding |
4/357 |
22/18432 |
0.0007679 |
0.0141503 |
0.012581 |
SELE/SIGLEC10/FCN1/ADIPOQ |
4 |
| MF |
GO:0042608 |
T cell receptor binding |
3/357 |
10/18432 |
0.0007814 |
0.0141503 |
0.012581 |
HLA-DRA/CD3G/LCK |
3 |
| MF |
GO:0050786 |
RAGE receptor binding |
3/357 |
10/18432 |
0.0007814 |
0.0141503 |
0.012581 |
FPR1/S100A9/S100A8 |
3 |
| MF |
GO:0140272 |
exogenous protein binding |
7/357 |
78/18432 |
0.0007833 |
0.0141503 |
0.012581 |
CD80/CCR5/CXCR4/SLAMF1/CR1/CDK1/CR2 |
7 |
| MF |
GO:0001653 |
peptide receptor activity |
10/357 |
153/18432 |
0.0008123 |
0.0142145 |
0.0126381 |
GPR84/CCR5/CXCR4/FPR1/CCR4/CXCR6/CCR2/CCR7/FPR2/NPY1R |
10 |
| MF |
GO:0019865 |
immunoglobulin binding |
4/357 |
24/18432 |
0.001082 |
0.0183612 |
0.0163249 |
FCGR1A/FCGR3A/MS4A1/FCAR |
4 |
| MF |
GO:0042169 |
SH2 domain binding |
5/357 |
41/18432 |
0.0011201 |
0.0184483 |
0.0164024 |
SLAMF1/SIGLEC10/LAX1/SIT1/LCK |
5 |
| MF |
GO:0016004 |
phospholipase activator activity |
3/357 |
14/18432 |
0.0022377 |
0.0358035 |
0.0318328 |
CCL3/CCL8/LCK |
3 |
| MF |
GO:0036041 |
long-chain fatty acid binding |
3/357 |
15/18432 |
0.0027573 |
0.0428909 |
0.0381342 |
S100A9/S100A8/FABP4 |
3 |
|