{"text_format":"3","workbook":"xls","n_sheets":1,"sheets":["F24A080000241_J240513022-first-"],"not_rendered":{"external_links":1,"defined_names":1},"read":"whole","date_system":"1900","formulas":"cached_only"}

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["Protein","ASFV","MOCK","GO Biological_Process","GO Molecular_Function","GO Cellular_Component","Protein-or-Domain","Score","E-Value","KOG-ID","Function-Description",null,"Code","Functional-Categories","Family","ko_id:rank:evalue:score:subject_id:ko_definition","Protein-Volcano","Intensity(MOCK)-ori","Intensity(ASFV)-ori","ratio","pvalue","adj_pvalue","Class","Description"]
["XP_064458638.1",14.09484259,9.325991763,"GO:0000349//generation of catalytic spliceosome for first transesterification step;GO:0006396//RNA processing",null,"GO:0071010//prespliceosome;GO:0071013//catalytic step 2 spliceosome;GO:0071012//catalytic step 1 spliceosome;GO:0071014//post-mRNA release spliceosomal complex;GO:0000974//Prp19 complex",7303287,1151.7,0,"KOG2047","mRNA splicing factor",null,"A","RNA processing and modification","INFORMATION STORAGE AND PROCESSING","K12867|1|0.0e+00|1514.2|isc:IscW_ISCW023297|pre-mRNA-splicing factor SYF1","XP_064458638.1","11226.0445347857;","1322246.29964919;",0.008490131,"NA","NA","Down","pre-mRNA-splicing factor syf1 homolog [Ornithodoros turicata]"]
["XP_064484003.1",10.72185909,8.066681976,{"$nulls":3},7292359,3984.9,0,"KOG0517","Beta-spectrin",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K06115|1|0.0e+00|4316.1|bter:100651603|spectrin beta","XP_064484003.1","3186.51134656806;","45336.1086455014;",0.070286389,"NA","NA","Down","spectrin beta chain, non-erythrocytic 1-like isoform X3 [Ornithodoros turicata]"]
["JAW01036.1",10.60609359,8.007173933,{"$nulls":3},7301622,462.6,{"v":8.2e-130,"d":"8.20E-130"},"KOG2220","Predicted signal transduction protein",null,"R","General function prediction only","POORLY CHARACTERIZED","K12200|1|2.9e-154|549.3|zne:110840640|programmed cell death 6-interacting protein","JAW01036.1","3002.42007094858;","40380.1493528605;",0.074353862,"NA","NA","Down","Longevity assurance factor, partial [Ornithodoros moubata]"]
["JAW03042.1",12.10034583,9.900143914,"GO:0090307//mitotic spindle assembly;GO:0031175//neuron projection development;GO:1990182//exosomal secretion;GO:0072659//protein localization to plasma membrane;GO:0030953//astral microtubule organization;GO:0006887//exocytosis;GO:0007080//mitotic metaphase plate congression;GO:0032402//melanosome transport;GO:0010634//positive regulation of epithelial cell migration;GO:0036258//multivesicular body assembly;GO:0072594//establishment of protein localization to organelle;GO:0060627//regulation of vesicle-mediated transport;GO:0010796//regulation of multivesicular body size;GO:0010971//positive regulation of G2/M transition of mitotic cell cycle;GO:0000910//cytokinesis;GO:0090150//establishment of protein localization to membrane;GO:0045773//positive regulation of axon extension;GO:0015031//protein transport","GO:0005525//GTP binding;GO:0008017//microtubule binding;GO:0003924//GTPase activity;GO:0031489//myosin V binding","GO:0005802//trans-Golgi network;GO:0055038//recycling endosome membrane;GO:0055037//recycling endosome;GO:0030424//axon;GO:0070062//extracellular exosome;GO:0005813//centrosome;GO:0005771//multivesicular body;GO:0005739//mitochondrion;GO:0000922//spindle pole;GO:0048471//perinuclear region of cytoplasm;GO:0032154//cleavage furrow;GO:0005886//plasma membrane;GO:0043234//protein complex;GO:0005828//kinetochore microtubule;GO:0045335//phagocytic vesicle","Hs4758984",357.1,{"v":2.1e-98,"d":"2.10E-98"},"KOG0087","GTPase Rab11/YPT3, small G protein superfamily",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K07904|1|1.7e-103|379.4|tut:107365615|Ras-related protein Rab-11A!K07905|2|3.1e-100|368.6|bfo:BRAFLDRAFT_266781|Ras-related protein Rab-11B","JAW03042.1","19933.2389044367;","179934.078969351;",0.110780787,"NA","NA","Down","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAV99682.1",10.56535296,8.398192667,null,"GO:0005524//ATP binding;GO:0032440//2-alkenal reductase [NAD(P)] activity",null,"Hs20547107",740,{"v":4.4e-213,"d":"4.40E-213"},"KOG0103","Molecular chaperones HSP105/HSP110/SSE1, HSP70 superfamily",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K09489|1|9.7e-216|754.2|ola:101166806|heat shock 70kDa protein 4!K09485|4|1.2e-213|747.3|lhu:105679170|heat shock protein 110kDa","JAV99682.1","4439.03667638095;","38768.097722482;",0.114502308,"NA","NA","Down","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAV99642.1",11.22632232,9.134447739,"GO:0015992//proton transport",null,"GO:0016471//vacuolar proton-transporting V-type ATPase complex",7300533,129.8,{"v":3e-30,"d":"3.00E-30"},"KOG1772","Vacuolar H+-ATPase V1 sector, subunit G",null,"C","Energy production and conversion","METABOLISM","K02152|1|2.1e-39|165.6|isc:IscW_ISCW013692|V-type H+-transporting ATPase subunit G","JAV99642.1","9269.15721101571;","75080.9634698153;",0.123455491,"NA","NA","Down","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAV99985.1",10.91722449,8.890742641,null,"GO:0046983//protein dimerization activity",null,"Hs19923193",384.8,{"v":1.6e-106,"d":"1.60E-106"},"KOG1308","Hsp70-interacting protein Hip/Transient component of progesterone receptor complexes and an Hsp70-binding protein",null,"OT","Posttranslational modification, protein turnover, chaperones;Signal transduction mechanisms","CELLULAR PROCESSES AND SIGNALING;CELLULAR PROCESSES AND SIGNALING","K09560|1|5.1e-108|395.2|lcm:102351459|suppressor of tumorigenicity protein 13","JAV99985.1","7264.41202771462;","55117.6072493978;",0.131798392,"NA","NA","Down","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW03012.1",11.2746228,9.401164012,"GO:0032418//lysosome localization;GO:0051301//cell division;GO:0007059//chromosome segregation;GO:0007264//small GTPase mediated signal transduction;GO:0007049//cell cycle","GO:0048487//beta-tubulin binding;GO:0019003//GDP binding;GO:0043014//alpha-tubulin binding;GO:0005525//GTP binding","GO:0005819//spindle;GO:0070062//extracellular exosome;GO:0030496//midbody;GO:0005622//intracellular;GO:0005765//lysosomal membrane;GO:0051233//spindle midzone;GO:0031902//late endosome membrane","Hs8922601",344,{"v":1.6e-94,"d":"1.60E-94"},"KOG0075","GTP-binding ADP-ribosylation factor-like protein",null,"R","General function prediction only","POORLY CHARACTERIZED","K07955|1|1.1e-93|346.7|mze:101468561|ADP-ribosylation factor-like protein 8","JAW03012.1","12102.4599378545;","78796.4164278845;",0.153591502,"NA","NA","Down","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW04388.1",11.15792657,9.30050964,"GO:0006412//translation","GO:0003735//structural constituent of ribosome;GO:0019843//rRNA binding","GO:0022626//cytosolic ribosome;GO:0005840//ribosome",7294504,448.4,{"v":8.5e-126,"d":"8.50E-126"},"KOG0378","40S ribosomal protein S4",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K02987|1|1.2e-127|459.9|zne:110828705|small subunit ribosomal protein S4e","JAW04388.1","10943.5950816024;","70117.4216201172;",0.156075264,"NA","NA","Down","40S ribosomal protein S4, partial [Ornithodoros moubata]"]
["JAV98667.1",10.83636979,9.000744378,"GO:0008152//metabolic process","GO:0016787//hydrolase activity",{"$nulls":10},"K21604|1|6.6e-11|72.8|rss:109441095|jasmonoyl-L-amino acid hydrolase [EC:3.5.1.127]","JAV98667.1","8109.11792876284;","50836.4955348553;",0.159513708,"NA","NA","Down","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW05217.1",9.516703676,7.747621085,"GO:0006098//pentose-phosphate shunt;GO:0019521//D-gluconate metabolic process","GO:0004616//phosphogluconate dehydrogenase (decarboxylating) activity",null,"Hs18545097",770.8,{"v":1.4e-222,"d":"1.40E-222"},"KOG2653","6-phosphogluconate dehydrogenase",null,"G","Carbohydrate transport and metabolism","METABOLISM","K00033|1|2.9e-239|831.6|isc:IscW_ISCW010101|6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343]","JAW05217.1","2316.05615545313;","13584.757572689;",0.170489325,"NA","NA","Down","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAV99766.1",11.02815757,9.317639996,null,"GO:0005094//Rho GDP-dissociation inhibitor activity","GO:0005737//cytoplasm",7293721,229.9,{"v":3.6e-60,"d":"3.60E-60"},"KOG3205","Rho GDP-dissociation inhibitor",null,"T","Signal transduction mechanisms","CELLULAR PROCESSES AND SIGNALING","K12462|1|3.2e-88|328.6|isc:IscW_ISCW020878|Rho GDP-dissociation inhibitor","JAV99766.1","11132.6776677251;","61584.0119078497;",0.180772206,"NA","NA","Down","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAV98715.1",10.84412557,9.150971848,{"$nulls":3},"Hs4507195",899.8,{"v":3.9e-261,"d":"3.90E-261"},"KOG0517","Beta-spectrin",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K06115|1|0.0e+00|1163.3|nvi:100114310|spectrin beta","JAV98715.1","9423.59423011594;","51232.3050132455;",0.183938517,"NA","NA","Down","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW02602.1",11.55283932,9.861737705,null,"GO:0016740//transferase activity;GO:0004867//serine-type endopeptidase inhibitor activity","GO:0005615//extracellular space","Hs13489087",285,{"v":1.8e-76,"d":"1.80E-76"},"KOG2392","Serpin UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase",null,"V","Defense mechanisms","CELLULAR PROCESSES AND SIGNALING","K13963|1|8.8e-90|334.7|isc:IscW_ISCW018607|serpin B","JAW02602.1","19182.1934769493;","104072.112122635;",0.184316366,"NA","NA","Down","UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase, partial [Ornithodoros moubata]"]
["XP_064484792.1",10.26755365,8.631352689,"GO:0030163//protein catabolic process","GO:0008233//peptidase activity;GO:0005524//ATP binding;GO:0036402//proteasome-activating ATPase activity","GO:0005737//cytoplasm",7290699,701.4,{"v":8.6e-202,"d":"8.60E-202"},"KOG0651","26S proteasome regulatory complex, ATPase RPT4",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K03064|1|3.2e-207|724.9|zne:110835498|26S proteasome regulatory subunit T4","XP_064484792.1","5604.65448213744;","28783.3865894503;",0.194718383,"NA","NA","Down","26S proteasome regulatory subunit 10B [Ornithodoros turicata]"]
["JAW01898.1",10.51628894,8.928692517,"GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination","GO:0004843//thiol-dependent ubiquitin-specific protease activity;GO:0008270//zinc ion binding",null,"Hs4507855",409.1,{"v":7.2e-114,"d":"7.20E-114"},"KOG0944","Ubiquitin-specific protease UBP14",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K11836|1|1.9e-117|426.4|lak:106159070|ubiquitin carboxyl-terminal hydrolase 5/13 [EC:3.4.19.12]","JAW01898.1","7545.39344839698;","36911.8877548588;",0.204416352,"NA","NA","Down","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAV99837.1",11.84383461,10.27842033,null,"GO:0016491//oxidoreductase activity",null,"Hs4506359",316.2,{"v":4.5e-86,"d":"4.50E-86"},"KOG4022","Dihydropteridine reductase DHPR/QDPR",null,"E","Amino acid transport and metabolism","METABOLISM","K00357|1|1.9e-87|326.2|pgc:109854551|dihydropteridine reductase [EC:1.5.1.34]","JAV99837.1","29097.8722013846;","139223.330128793;",0.209001409,"NA","NA","Down","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW00388.1",10.65247191,9.091075245,"GO:0071048//nuclear retention of unspliced pre-mRNA at the site of transcription;GO:0008380//RNA splicing;GO:0000350//generation of catalytic spliceosome for second transesterification step",null,"GO:0046540//U4/U6 x U5 tri-snRNP complex;GO:0071021//U2-type post-spliceosomal complex;GO:0005682//U5 snRNP;GO:0005681//spliceosomal complex","Hs4506123",110.2,{"v":3e-24,"d":"3.00E-24"},"KOG2808","U5 snRNP-associated RNA splicing factor",null,"A","RNA processing and modification","INFORMATION STORAGE AND PROCESSING","K12817|1|1.1e-48|196.8|isc:IscW_ISCW001590|pre-mRNA-splicing factor 18","JAW00388.1","8875.72450076037;","42297.019776942;",0.209842787,"NA","NA","Down","hypothetical protein, partial [Ornithodoros moubata]"]
["JAV99627.1",11.9320344,10.41404327,"GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process","GO:0004298//threonine-type endopeptidase activity","GO:0005737//cytoplasm;GO:0019773//proteasome core complex, alpha-subunit complex;GO:0005634//nucleus","Hs4506187",370.2,{"v":2.7e-102,"d":"2.70E-102"},"KOG0176","20S proteasome, regulatory subunit alpha type PSMA5/PUP2",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K02729|1|1.3e-110|403.3|dpx:DAPPUDRAFT_231717|20S proteasome subunit alpha 5 [EC:3.4.25.1]","JAV99627.1","33324.3377716276;","152060.599226775;",0.219151693,"NA","NA","Down","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW02358.1",11.39909171,9.903922247,null,"GO:0004725//protein tyrosine phosphatase activity;GO:0005509//calcium ion binding",null,7292157,1709.9,0,"KOG0040","Ca2+-binding actin-bundling protein (spectrin), alpha chain (EF-Hand protein superfamily)",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K06114|1|0.0e+00|2029.2|isc:IscW_ISCW000012|spectrin alpha","JAW02358.1","20008.6957749857;","89240.6305185876;",0.224210605,"NA","NA","Down","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW06393.1",10.53650233,9.093058061,"GO:0042254//ribosome biogenesis","GO:0016829//lyase activity","GO:0005840//ribosome",7296522,463,{"v":4.1e-130,"d":"4.10E-130"},"KOG0815","60S acidic ribosomal protein P0",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K02941|1|9.9e-164|580.1|isc:IscW_ISCW007303|large subunit ribosomal protein LP0","JAW06393.1","8893.3408907718;","37665.5939263529;",0.23611312,"NA","NA","Down","Uncharacterized protein, partial [Ornithodoros moubata]"]
["XP_064472172.1",11.18363361,9.787936987,"GO:0007016//cytoskeletal anchoring at plasma membrane;GO:0007155//cell adhesion","GO:0005200//structural constituent of cytoskeleton;GO:0005158//insulin receptor binding;GO:0051015//actin filament binding","GO:0005856//cytoskeleton;GO:0001726//ruffle;GO:0005925//focal adhesion","Hs22035665",2716,0,"KOG4261","Talin",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K06271|1|0.0e+00|3262.2|zne:110830102|talin","XP_064472172.1","17817.5104640636;","71943.3013595112;",0.247660451,"NA","NA","Down","talin-2-like isoform X2 [Ornithodoros turicata] >XP_064472173.1 talin-2-like isoform X2 [Ornithodoros turicata] >XP_064472174.1 talin-2-like isoform X2 [Ornithodoros turicata]"]
["JAV98872.1",9.341002339,7.955582077,"GO:0006030//chitin metabolic process","GO:0008061//chitin binding","GO:0005576//extracellular region",7294450,407.9,{"v":6.1e-113,"d":"6.10E-113"},"KOG1216","von Willebrand factor and related coagulation proteins",null,"WV","Extracellular structures;Defense mechanisms","CELLULAR PROCESSES AND SIGNALING;CELLULAR PROCESSES AND SIGNALING","K03900|1|1.4e-136|491.9|bmor:692743|von Willebrand factor!K10955|5|1.6e-121|441.8|lak:106167614|mucin-2","JAV98872.1","2851.4476085506;","11395.8250013922;",0.25021862,"NA","NA","Down","SCO-spondin, partial [Ornithodoros moubata]"]
["JAW01787.1",10.41911178,9.043205927,null,"GO:0004725//protein tyrosine phosphatase activity;GO:0005509//calcium ion binding",null,7292157,941.8,{"v":6.2e-274,"d":"6.20E-274"},"KOG0040","Ca2+-binding actin-bundling protein (spectrin), alpha chain (EF-Hand protein superfamily)",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K06114|1|2.6e-296|1021.5|zne:110836766|spectrin alpha","JAW01787.1","8460.85851599112;","33493.6710334352;",0.252610665,"NA","NA","Down","40S ribosomal protein S9, partial [Ornithodoros moubata]"]
["XP_064478617.1",9.484820649,8.130050781,"GO:0030163//protein catabolic process","GO:0008233//peptidase activity;GO:0005524//ATP binding;GO:0036402//proteasome-activating ATPase activity","GO:0005737//cytoplasm",7301041,755.4,{"v":5.4e-218,"d":"5.40E-218"},"KOG0652","26S proteasome regulatory complex, ATPase RPT5",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K03065|1|1.0e-219|766.5|dpx:DAPPUDRAFT_299812|26S proteasome regulatory subunit T5","XP_064478617.1","3394.97196170335;","13158.4662149285;",0.258006663,"NA","NA","Down","26S proteasome regulatory subunit 6A-B [Ornithodoros turicata]"]
["JAV99731.1",11.25540508,9.90981843,"GO:0031111//negative regulation of microtubule polymerization or depolymerization;GO:0006457//protein folding;GO:0031115//negative regulation of microtubule polymerization;GO:0006825//copper ion transport;GO:0030521//androgen receptor signaling pathway;GO:0061077//chaperone-mediated protein folding;GO:0030850//prostate gland development;GO:0006463//steroid hormone receptor complex assembly;GO:0010977//negative regulation of neuron projection development;GO:0046661//male sex differentiation;GO:0031503//protein complex localization;GO:1900034//regulation of cellular response to heat;GO:0007566//embryo implantation","GO:0031072//heat shock protein binding;GO:0005528//FK506 binding;GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005524//ATP binding;GO:0005525//GTP binding;GO:0035259//glucocorticoid receptor binding;GO:0032767//copper-dependent protein binding;GO:0048156//tau protein binding;GO:0030674//protein binding, bridging;GO:0051219//phosphoprotein binding;GO:0003723//RNA binding","GO:0005874//microtubule;GO:0005737//cytoplasm;GO:0070062//extracellular exosome;GO:0005739//mitochondrion;GO:0005654//nucleoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0043025//neuronal cell body;GO:0043234//protein complex;GO:0044295//axonal growth cone;GO:0005829//cytosol","Hs4503729",440.7,{"v":3.2e-123,"d":"3.20E-123"},"KOG0543","FKBP-type peptidyl-prolyl cis-trans isomerase",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K09571|1|8.1e-122|441.4|dre:321795|FK506-binding protein 4/5 [EC:5.2.1.8]","JAV99731.1","20127.0191945625;","77296.5866419537;",0.260386908,"NA","NA","Down","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW03194.1",10.58099435,9.243740961,null,"GO:0016787//hydrolase activity","GO:0005634//nucleus",7292033,252.7,{"v":8.1e-67,"d":"8.10E-67"},"KOG4048","Uncharacterized conserved protein",null,"S","Function unknown","POORLY CHARACTERIZED",null,"JAW03194.1","10339.6465107105;","39379.251821299;",0.262565845,"NA","NA","Down","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW02758.1",10.84740586,9.540377315,"GO:0006796//phosphate-containing compound metabolic process","GO:0000287//magnesium ion binding;GO:0004427//inorganic diphosphatase activity","GO:0005737//cytoplasm",7291807,383.3,{"v":4.1e-106,"d":"4.10E-106"},"KOG1626","Inorganic pyrophosphatase/Nucleosome remodeling factor, subunit NURF38",null,"C","Energy production and conversion","METABOLISM","K11726|1|7.2e-138|494.2|isc:IscW_ISCW000237|nucleosome-remodeling factor 38 kDa subunit [EC:3.6.1.1]","JAW02758.1","13910.1951595278;","51400.6377799172;",0.270623007,"NA","NA","Down","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW06446.1",10.13861803,8.876454648,"GO:0016192//vesicle-mediated transport;GO:0006886//intracellular protein transport;GO:0048268//clathrin coat assembly","GO:0032051//clathrin light chain binding;GO:0005198//structural molecule activity","GO:0071439//clathrin complex;GO:0030130//clathrin coat of trans-Golgi network vesicle;GO:0030132//clathrin coat of coated pit",7293138,1855.9,0,"KOG0985","Vesicle coat protein clathrin, heavy chain",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K04646|1|0.0e+00|1975.7|zne:110826899|clathrin heavy chain","JAW06446.1","7161.35614614774;","25301.4763887455;",0.283041038,"NA","NA","Down","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAV99946.1",10.45429989,9.198877369,"GO:0008152//metabolic process;GO:0006635//fatty acid beta-oxidation;GO:0071456//cellular response to hypoxia;GO:1901029//negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway;GO:1902109//negative regulation of mitochondrial membrane permeability involved in apoptotic process","GO:0003723//RNA binding;GO:0003988//acetyl-CoA C-acyltransferase activity;GO:0003985//acetyl-CoA C-acetyltransferase activity;GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups","GO:0070062//extracellular exosome;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane","Hs5174429",490,{"v":3.9e-138,"d":"3.90E-138"},"KOG1391","Acetyl-CoA acetyltransferase",null,"I","Lipid transport and metabolism","METABOLISM","K07508|1|2.6e-153|545.8|isc:IscW_ISCW002623|acetyl-CoA acyltransferase 2 [EC:2.3.1.16]","JAV99946.1","9886.02446791606;","34693.2315598975;",0.284955423,"NA","NA","Down","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAV99617.1",10.15372747,8.910313833,"GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0002184//cytoplasmic translational termination","GO:0003924//GTPase activity;GO:0003746//translation elongation factor activity;GO:0003747//translation release factor activity;GO:0004781//sulfate adenylyltransferase (ATP) activity;GO:0005525//GTP binding","GO:0005829//cytosol;GO:0018444//translation release factor complex",7297950,714.5,{"v":1.4e-205,"d":"1.40E-205"},"KOG0459","Polypeptide release factor 3",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K03267|1|4.9e-299|1030.4|isc:IscW_ISCW018746|peptide chain release factor subunit 3","JAV99617.1","7407.9856063078;","25686.6702872555;",0.288398049,"NA","NA","Down","Uncharacterized protein, partial [Ornithodoros moubata]"]
["ABI52667.1",10.11692678,8.878379734,"GO:0030154//cell differentiation;GO:0002181//cytoplasmic translation;GO:0006412//translation","GO:0016787//hydrolase activity;GO:0003735//structural constituent of ribosome","GO:0005829//cytosol;GO:0005634//nucleus;GO:0022627//cytosolic small ribosomal subunit;GO:0005840//ribosome","Hs14755682",395.6,{"v":6.4e-110,"d":"6.40E-110"},"KOG1628","40S ribosomal protein S3A",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K02984|1|7.8e-111|404.1|bfo:BRAFLDRAFT_69722|small subunit ribosomal protein S3Ae","ABI52667.1","7175.1556516567;","24758.5653034439;",0.289804985,"NA","NA","Down","40S ribosomal protein S3a, partial [Argas monolakensis]"]
["JAW02332.1",11.70638197,10.51231263,null,"GO:0004329//formate-tetrahydrofolate ligase activity;GO:0005524//ATP binding;GO:0004488//methylenetetrahydrofolate dehydrogenase (NADP+) activity","GO:0005737//cytoplasm","Hs13699868",358.6,{"v":1e-98,"d":"1.00E-98"},"KOG4230","C1-tetrahydrofolate synthase",null,"H","Coenzyme transport and metabolism","METABOLISM","K00288|1|3.3e-108|395.6|dpe:6594045|methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3]","JAW02332.1","36765.4059538609;","121343.660587717;",0.302985799,"NA","NA","Down","Ribosomal protein S18, partial [Ornithodoros moubata]"]
["JAV99389.1",9.629449307,8.467251678,"GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0006289//nucleotide-excision repair","GO:0003684//damaged DNA binding","GO:0005634//nucleus","Hs4506387",285.8,{"v":8.8e-77,"d":"8.80E-77"},"KOG0011","Nucleotide excision repair factor NEF2, RAD23 component",null,"L","Replication, recombination and repair","INFORMATION STORAGE AND PROCESSING","K10839|1|1.9e-95|353.2|isc:IscW_ISCW011548|UV excision repair protein RAD23","JAV99389.1","4756.42530308693;","15206.0599226775;",0.312798011,"NA","NA","Down","Uv excision repair protein rad23, partial [Ornithodoros moubata]"]
["JAW03594.1",12.8933517,11.75740254,{"$nulls":3},7293608,214.9,{"v":1.1e-55,"d":"1.10E-55"},"KOG3591","Alpha crystallins",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K09542|1|8.3e-19|97.8|sko:100371573|crystallin, alpha B","JAW03594.1","127695.339062875;","397659.622312205;",0.321117186,"NA","NA","Down","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAR86351.1",10.52504263,9.390848985,null,"GO:0005544//calcium-dependent phospholipid binding;GO:0005509//calcium ion binding",null,"Hs4809279",151.8,{"v":9.6e-37,"d":"9.60E-37"},"KOG0819","Annexin",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K17095|1|4.3e-40|168.3|aqu:100638289|annexin A7/11","JAR86351.1","11978.2643882739;","37236.4211969106;",0.321681408,"NA","NA","Down","annexin a7 like, partial [Alectorobius mimon]"]
["AAS59855.1",10.31267408,9.218493049,"GO:0007034//vacuolar transport",null,"GO:0005622//intracellular","Hs20560209",273.5,{"v":3.2e-73,"d":"3.20E-73"},"KOG1656","Protein involved in glucose derepression and pre-vacuolar endosome protein sorting",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K12194|1|1.4e-79|300.1|crg:105323904|charged multivesicular body protein 4","AAS59855.1","10081.8600035432;","30111.8505858865;",0.334813697,"NA","NA","Down","KOG1656-like protein [Ornithodoros moubata]"]
["JAW02555.1",10.20044069,9.108585611,null,"GO:0003774//motor activity;GO:0005524//ATP binding","GO:0016459//myosin complex",7297714,1167.5,0,"KOG0164","Myosin class I heavy chain",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K10356|1|0.0e+00|1302.0|lak:106167411|myosin I","JAW02555.1","9032.51037186213;","26915.0445305355;",0.335593365,"NA","NA","Down","Fibrinogen, partial [Ornithodoros moubata]"]
["JAW03308.1",10.17574103,9.115420864,"GO:0006412//translation","GO:0003735//structural constituent of ribosome","GO:0022627//cytosolic small ribosomal subunit;GO:0005840//ribosome","Hs14277700",211.5,{"v":8.9e-55,"d":"8.90E-55"},"KOG3406","40S ribosomal protein S12",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K02951|1|1.9e-60|235.7|isc:IscW_ISCW017361|small subunit ribosomal protein S12e","JAW03308.1","9094.46134340233;","26258.3950893747;",0.346344905,"NA","NA","Down","40S ribosomal protein S12, partial [Ornithodoros moubata]"]
["JAW05486.1",11.98411027,10.93556044,"GO:0051017//actin filament bundle assembly;GO:0051639//actin filament network formation;GO:0051764//actin crosslink formation","GO:0004725//protein tyrosine phosphatase activity;GO:0051015//actin filament binding;GO:0003779//actin binding;GO:0005509//calcium ion binding","GO:0005737//cytoplasm;GO:0032432//actin filament bundle;GO:0005884//actin filament",7293343,854.7,{"v":9.6e-248,"d":"9.60E-248"},"KOG0046","Ca2+-binding actin-bundling protein (fimbrin/plastin), EF-Hand protein superfamily",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K17336|1|1.8e-286|988.8|isc:IscW_ISCW012584|plastin-3","JAW05486.1","56137.5628364334;","160189.100392183;",0.350445584,"NA","NA","Down","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAV98989.1",10.23646417,9.219075324,"GO:0006895//Golgi to endosome transport;GO:0030100//regulation of endocytosis;GO:0090382//phagosome maturation;GO:0042742//defense response to bacterium;GO:0032456//endocytic recycling","GO:0003924//GTPase activity;GO:0004767//sphingomyelin phosphodiesterase activity;GO:0005525//GTP binding","GO:0005829//cytosol;GO:0005802//trans-Golgi network;GO:0045335//phagocytic vesicle;GO:0005768//endosome;GO:0055037//recycling endosome","Hs19923483",390.2,{"v":2.3e-108,"d":"2.30E-108"},"KOG0097","GTPase Rab14, small G protein superfamily",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K07881|1|2.5e-110|402.1|isc:IscW_ISCW013805|Ras-related protein Rab-14","JAV98989.1","10087.732133547;","27902.2934593939;",0.361537741,"NA","NA","Down","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAV99551.1",11.30469027,10.31609526,"GO:0019563//glycerol catabolic process;GO:0046166//glyceraldehyde-3-phosphate biosynthetic process;GO:0006098//pentose-phosphate shunt;GO:0006096//glycolytic process;GO:0006094//gluconeogenesis","GO:0004807//triose-phosphate isomerase activity","GO:0005829//cytosol",7301903,372.9,{"v":4.3e-103,"d":"4.30E-103"},"KOG1643","Triosephosphate isomerase",null,"G","Carbohydrate transport and metabolism","METABOLISM","K01803|1|6.8e-112|407.5|isc:IscW_ISCW008869|triosephosphate isomerase (TIM) [EC:5.3.1.1]","JAV99551.1","30215.0449346097;","81201.603526455;",0.372099117,"NA","NA","Down","Triosephosphate isomerase, partial [Ornithodoros moubata]"]
["XP_064484361.1",11.03329101,10.05787166,"GO:0034314//Arp2/3 complex-mediated actin nucleation;GO:0060319//primitive erythrocyte differentiation","GO:0003779//actin binding;GO:0005524//ATP binding","GO:0005737//cytoplasm;GO:0005885//Arp2/3 protein complex;GO:0042995//cell projection","Hs5031571",671.4,{"v":9.4e-193,"d":"9.40E-193"},"KOG0677","Actin-related protein Arp2/3 complex, subunit Arp2",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K17260|1|7.1e-196|687.2|dpx:DAPPUDRAFT_209234|actin-related protein 2","XP_064484361.1","23338.7807001469;","61900.9627928442;",0.377034212,"NA","NA","Down","actin-related protein 2-B-like [Ornithodoros turicata]"]
["JAV99055.1",11.18074157,10.2093734,"GO:0034314//Arp2/3 complex-mediated actin nucleation","GO:0051015//actin filament binding","GO:0005885//Arp2/3 protein complex",7298100,452.2,{"v":8.4e-127,"d":"8.40E-127"},"KOG1523","Actin-related protein Arp2/3 complex, subunit ARPC1/p41-ARC",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K05757|1|3.6e-149|531.9|isc:IscW_ISCW011129|actin related protein 2/3 complex, subunit 1A/1B","JAV99055.1","27156.5460221247;","71735.5392961416;",0.378564743,"NA","NA","Down","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW05533.1",10.6945967,9.730209417,null,"GO:0004027//alcohol sulfotransferase activity",{"$nulls":11},"JAW05533.1","16818.073937415;","44116.8334706901;",0.381216706,"NA","NA","Down","Sulfotransferase, partial [Ornithodoros moubata]"]
["XP_064459452.1",9.970768091,9.008570583,{"$nulls":3},"Hs4826659",477.2,{"v":1.8e-134,"d":"1.80E-134"},"KOG3174","F-actin capping protein, beta subunit",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K10365|1|1.7e-135|486.1|zne:110828160|capping protein (actin filament) muscle Z-line, beta","XP_064459452.1","8172.83053930419;","21391.9099700098;",0.3820524,"NA","NA","Down","F-actin-capping protein subunit beta [Ornithodoros turicata]"]
["XP_064467929.1",12.33653498,11.37926681,"GO:0006352//DNA-templated transcription, initiation;GO:0006334//nucleosome assembly","GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity","GO:0005634//nucleus;GO:0000786//nucleosome","Hs4504301",203.4,{"v":1.9e-52,"d":"1.90E-52"},"KOG3467","Histone H4",null,"B","Chromatin structure and dynamics","INFORMATION STORAGE AND PROCESSING","K11254|1|8.1e-51|203.4|sko:100369311|histone H4","XP_064467929.1","87488.8649267805;","227871.004685501;",0.383940313,"NA","NA","Down","histone H4-like [Ornithodoros turicata]"]
["JAW06754.1",10.90557345,9.957753112,"GO:0006096//glycolytic process","GO:0004618//phosphoglycerate kinase activity;GO:0005524//ATP binding",null,"Hs4505763",602.8,{"v":4.7e-172,"d":"4.70E-172"},"KOG1367","3-phosphoglycerate kinase",null,"G","Carbohydrate transport and metabolism","METABOLISM","K00927|1|7.9e-191|670.6|isc:IscW_ISCW015616|phosphoglycerate kinase [EC:2.7.2.3]","JAW06754.1","21115.2986742039;","54479.1559451745;",0.387584909,"NA","NA","Down","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW06905.1",12.84282484,11.90487623,"GO:0046034//ATP metabolic process;GO:0015991//ATP hydrolysis coupled proton transport","GO:0046961//proton-transporting ATPase activity, rotational mechanism;GO:0005524//ATP binding","GO:0033180//proton-transporting V-type ATPase, V1 domain","HsM4502307",1009.6,{"v":2.1e-294,"d":"2.10E-294"},"KOG1352","Vacuolar H+-ATPase V1 sector, subunit A",null,"C","Energy production and conversion","METABOLISM","K02145|1|1.7e-291|1005.4|tca:663322|V-type H+-transporting ATPase subunit A [EC:7.1.2.2]","JAW06905.1","147986.484291044;","378066.294876183;",0.391429985,"NA","NA","Down","Uncharacterized protein, partial [Ornithodoros moubata]"]
["XP_064486388.1",10.67428244,9.765355516,"GO:1901565//organonitrogen compound catabolic process","GO:0019239//deaminase activity;GO:0003723//RNA binding","GO:0005737//cytoplasm;GO:0070062//extracellular exosome;GO:0005634//nucleus","Hs5032215",151.4,{"v":1.2e-36,"d":"1.20E-36"},"KOG2317","Putative translation initiation inhibitor UK114/IBM1",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K09022|1|1.4e-48|196.4|isc:IscW_ISCW017587|2-iminobutanoate/2-iminopropanoate deaminase [EC:3.5.99.10]","XP_064486388.1","17419.6736563054;","43229.6742949879;",0.402956394,"NA","NA","Down","2-iminobutanoate/2-iminopropanoate deaminase-like [Ornithodoros turicata]"]
["JAV99098.1",10.63780825,9.742976507,"GO:0009072//aromatic amino acid family metabolic process","GO:0004334//fumarylacetoacetase activity",null,"Hs4557587",274.2,{"v":1.9e-73,"d":"1.90E-73"},"KOG2843","Fumarylacetoacetase",null,"G","Carbohydrate transport and metabolism","METABOLISM","K01555|1|3.7e-101|371.7|isc:IscW_ISCW020196|fumarylacetoacetase [EC:3.7.1.2]","JAV99098.1","17034.1683215552;","41681.3161438905;",0.408676354,"NA","NA","Down","Fumarylacetoacetase, partial [Ornithodoros moubata]"]
["JAV99942.1",11.98325788,11.09446668,"GO:0000086//G2/M transition of mitotic cell cycle;GO:0030705//cytoskeleton-dependent intracellular transport;GO:0051301//cell division;GO:0097711//ciliary basal body-plasma membrane docking;GO:0043066//negative regulation of apoptotic process;GO:0021634//optic nerve formation;GO:0010389//regulation of G2/M transition of mitotic cell cycle;GO:0007017//microtubule-based process","GO:0005200//structural constituent of cytoskeleton;GO:0005198//structural molecule activity;GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0019904//protein domain specific binding;GO:0046982//protein heterodimerization activity","GO:0055037//recycling endosome;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0005874//microtubule;GO:0005737//cytoplasm;GO:0070062//extracellular exosome;GO:0043209//myelin sheath;GO:0005634//nucleus;GO:0015630//microtubule cytoskeleton;GO:0005881//cytoplasmic microtubule;GO:0005829//cytosol;GO:0045121//membrane raft","Hs17986283",904.8,{"v":5.7e-263,"d":"5.70E-263"},"KOG1376","Alpha tubulin",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K07374|1|2.5e-261|904.8|xtr:100038123|tubulin alpha","JAV99942.1","65806.0248877083;","160052.614365152;",0.411152452,"NA","NA","Down","Tubulin alpha chain, partial [Ornithodoros moubata] >XP_064461202.1 tubulin alpha chain [Ornithodoros turicata]"]
["JAW05277.1",10.80007065,9.914373981,"GO:0007016//cytoskeletal anchoring at plasma membrane;GO:0007155//cell adhesion","GO:0005200//structural constituent of cytoskeleton;GO:0051015//actin filament binding","GO:0005856//cytoskeleton;GO:0001726//ruffle;GO:0005925//focal adhesion","Hs16753233",468.4,{"v":1.3e-131,"d":"1.30E-131"},"KOG4261","Talin",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K06271|1|4.6e-188|661.4|isc:IscW_ISCW023338|talin","JAW05277.1","20218.9180291221;","49024.2643981644;",0.41242675,"NA","NA","Down","Talin, partial [Ornithodoros moubata]"]
["JAT79171.1",11.20190992,10.32470641,{"$nulls":3},7299413,151.8,{"v":1.2e-36,"d":"1.20E-36"},"KOG1727","Microtubule-binding protein (translationally controlled tumor protein)",null,"DZ","Cell cycle control, cell division, chromosome partitioning;Cytoskeleton","CELLULAR PROCESSES AND SIGNALING;CELLULAR PROCESSES AND SIGNALING","K02941|1|3.4e-26|122.5|nai:NECAME_00662|large subunit ribosomal protein LP0!K01115|2|9.3e-24|114.4|crg:105332889|phospholipase D1/2 [EC:3.1.4.4]!K20301|3|1.3e-20|104.0|tsp:Tsp_05901|trafficking protein particle complex subunit 2","JAT79171.1","30476.3547197792;","73270.2488445359;",0.415944469,"NA","NA","Down","translationally controlled tumor protein, partial [Ornithodoros brasiliensis]"]
["XP_064466057.1",9.929151201,9.074699752,"GO:0051289//protein homotetramerization;GO:0051260//protein homooligomerization;GO:1901143//insulin catabolic process;GO:0050435//amyloid-beta metabolic process;GO:0042447//hormone catabolic process;GO:0097242//amyloid-beta clearance;GO:1901142//insulin metabolic process;GO:0006508//proteolysis;GO:0032461//positive regulation of protein oligomerization;GO:0010992//ubiquitin recycling;GO:0008286//insulin receptor signaling pathway;GO:0051291//protein heterooligomerization;GO:0010815//bradykinin catabolic process;GO:0008340//determination of adult lifespan;GO:0045861//negative regulation of proteolysis;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0045732//positive regulation of protein catabolic process","GO:0008270//zinc ion binding;GO:0016887//ATPase activity;GO:0001540//amyloid-beta binding;GO:0140036//ubiquitin-dependent protein binding;GO:0046872//metal ion binding;GO:0005524//ATP binding;GO:0004222//metalloendopeptidase activity;GO:0031626//beta-endorphin binding;GO:0042277//peptide binding;GO:0043559//insulin binding;GO:0001618//virus receptor activity;GO:0042802//identical protein binding;GO:0005102//receptor binding;GO:0042803//protein homodimerization activity","GO:0005782//peroxisomal matrix;GO:0031597//cytosolic proteasome complex;GO:0005737//cytoplasm;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005777//peroxisome;GO:0005739//mitochondrion;GO:0009986//cell surface;GO:0005886//plasma membrane;GO:0005829//cytosol","Hs4826770",1148.3,0,"KOG0959","N-arginine dibasic convertase NRD1 and related Zn2+-dependent endopeptidases, insulinase superfamily",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K01408|1|0.0e+00|1158.3|zne:110833158|insulysin [EC:3.4.24.56]","XP_064466057.1","8731.56370916681;","20519.9159084221;",0.425516544,"NA","NA","Down","insulin-degrading enzyme-like isoform X2 [Ornithodoros turicata]"]
["JAW05383.1",9.601301795,8.747731954,"GO:0006518//peptide metabolic process","GO:0046872//metal ion binding;GO:0004222//metalloendopeptidase activity","GO:0005758//mitochondrial intermembrane space","Hs4507491",433.3,{"v":5.5e-121,"d":"5.50E-121"},"KOG2089","Metalloendopeptidase family - saccharolysin & thimet oligopeptidase",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K01392|1|1.9e-156|556.6|isc:IscW_ISCW012570|thimet oligopeptidase [EC:3.4.24.15]","JAW05383.1","6296.39139658638;","14784.014796869;",0.425891849,"NA","NA","Down","Thimet oligopeptidase, partial [Ornithodoros moubata]"]
["JAW02537.1",10.31257335,9.494641982,"GO:0006068//ethanol catabolic process","GO:0004029//aldehyde dehydrogenase (NAD) activity;GO:0001758//retinal dehydrogenase activity;GO:0016491//oxidoreductase activity","GO:0070062//extracellular exosome;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix","Hs11436533",672.5,{"v":5.2e-193,"d":"5.20E-193"},"KOG2450","Aldehyde dehydrogenase",null,"C","Energy production and conversion","METABOLISM","K00128|1|3.4e-240|834.7|isc:IscW_ISCW023288|aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]","JAW02537.1","13288.3365921242;","30108.8175630636;",0.441343688,"NA","NA","Down","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAV99575.1",10.37934758,9.565781659,"GO:0006520//cellular amino acid metabolic process;GO:0009058//biosynthetic process;GO:0006533//aspartate catabolic process","GO:0004069//L-aspartate:2-oxoglutarate aminotransferase activity;GO:0080130//L-phenylalanine:2-oxoglutarate aminotransferase activity;GO:0008483//transaminase activity;GO:0030170//pyridoxal phosphate binding","GO:0005739//mitochondrion","Hs4504069",602.1,{"v":7.5e-172,"d":"7.50E-172"},"KOG1411","Aspartate aminotransferase/Glutamic oxaloacetic transaminase AAT1/GOT2",null,"E","Amino acid transport and metabolism","METABOLISM","K14455|1|1.2e-193|679.9|isc:IscW_ISCW020516|aspartate aminotransferase, mitochondrial [EC:2.6.1.1]","JAV99575.1","14268.10148326;","32187.9547081708;",0.443274561,"NA","NA","Down","Uncharacterized protein, partial [Ornithodoros moubata]"]
["XP_064460465.1",12.53785283,11.72591785,"GO:0016192//vesicle-mediated transport;GO:0006886//intracellular protein transport;GO:0048268//clathrin coat assembly","GO:0032051//clathrin light chain binding;GO:0005198//structural molecule activity","GO:0071439//clathrin complex;GO:0030130//clathrin coat of trans-Golgi network vesicle;GO:0030132//clathrin coat of coated pit","Hs4758012",2865.1,0,"KOG0985","Vesicle coat protein clathrin, heavy chain",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K04646|1|0.0e+00|3007.6|zne:110826899|clathrin heavy chain","XP_064460465.1","123737.523440306;","278689.302083418;",0.44399811,"NA","NA","Down","clathrin heavy chain 1 [Ornithodoros turicata]"]
["JAV98754.1",10.96217498,10.15840611,{"$nulls":3},7301873,252.7,{"v":1.1e-66,"d":"1.10E-66"},"KOG3720","Lysosomal & prostatic acid phosphatases",null,"I","Lipid transport and metabolism","METABOLISM","K14410|1|2.6e-74|283.5|zne:110837410|lysosomal acid phosphatase [EC:3.1.3.2]","JAV98754.1","25807.1305472489;","57651.6978179422;",0.447638691,"NA","NA","Down","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAV99769.1",13.49699516,12.70768986,"GO:0006508//proteolysis","GO:0103046//alanylglutamate dipeptidase activity;GO:0004180//carboxypeptidase activity;GO:0016805//dipeptidase activity;GO:0009014//succinyl-diaminopimelate desuccinylase activity;GO:0102008//cytosolic dipeptidase activity;GO:0008233//peptidase activity;GO:0046872//metal ion binding;GO:0008237//metallopeptidase activity","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0005654//nucleoplasm","Hs8922699",605.5,{"v":7.7e-173,"d":"7.70E-173"},"KOG2276","Metalloexopeptidases",null,"E","Amino acid transport and metabolism","METABOLISM","K08660|1|4.9e-207|724.5|isc:IscW_ISCW017703|cytosolic nonspecific dipeptidase [EC:3.4.13.18]","JAV99769.1","330277.952064351;","727227.88225;",0.454160188,"NA","NA","Down","Anserinase, partial [Ornithodoros moubata]"]
["XP_064456400.1",10.26401737,9.474894148,"GO:0006099//tricarboxylic acid cycle","GO:0000287//magnesium ion binding;GO:0004775//succinate-CoA ligase (ADP-forming) activity;GO:0016874//ligase activity;GO:0005524//ATP binding","GO:0005739//mitochondrion","Hs11321583_2",537.3,{"v":2.4e-152,"d":"2.40E-152"},"KOG2799","Succinyl-CoA synthetase, beta subunit",null,"C","Energy production and conversion","METABOLISM","K01900|1|6.2e-180|634.4|isc:IscW_ISCW011750|succinyl-CoA synthetase beta subunit [EC:6.2.1.4 6.2.1.5]","XP_064456400.1","13028.4948394555;","28681.7803248827;",0.454242892,"NA","NA","Down","succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial-like [Ornithodoros turicata]"]
["JAW02578.1",10.60710709,9.822832249,"GO:0048668//collateral sprouting;GO:0006629//lipid metabolic process","GO:0017040//ceramidase activity","GO:0005764//lysosome",{"$nulls":9},"K12348|1|1.3e-135|486.9|isc:IscW_ISCW010877|acid ceramidase [EC:3.5.1.23]","JAW02578.1","18450.2324719743;","40421.0951609699;",0.456450584,"NA","NA","Down","Translation elongation factor EF-1 alpha-Tu, partial [Ornithodoros moubata]"]
["BAE46505.1",11.29016755,10.50991397,"GO:0030036//actin cytoskeleton organization","GO:0005200//structural constituent of cytoskeleton;GO:0005524//ATP binding","GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0045121//membrane raft;GO:0005865//striated muscle thin filament",7290649,759.2,{"v":3.2e-219,"d":"3.20E-219"},"KOG0676","Actin and related proteins",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K05692|1|4.8e-218|760.8|nvi:100116604|actin beta/gamma 1","BAE46505.1","36677.3240038037;","80030.8567168104;",0.458289784,"NA","NA","Down","actin [Ornithodoros moubata]"]
["XP_064478774.1",9.729129012,8.971537445,"GO:0007015//actin filament organization;GO:0016477//cell migration;GO:0051017//actin filament bundle assembly;GO:0007163//establishment or maintenance of cell polarity;GO:0009653//anatomical structure morphogenesis","GO:0030674//protein binding, bridging;GO:0051015//actin filament binding","GO:0005737//cytoplasm;GO:0031941//filamentous actin",{"$nulls":9},"K17455|1|5.1e-191|671.4|isc:IscW_ISCW004404|fascin 1/2","XP_064478774.1","7875.70076111135;","16799.9134161186;",0.468794128,"NA","NA","Down","protein singed-like isoform X3 [Ornithodoros turicata]"]
["JAW03689.1",10.53762904,9.780178534,"GO:0006412//translation;GO:0000027//ribosomal large subunit assembly","GO:0003735//structural constituent of ribosome;GO:0003723//RNA binding","GO:0005840//ribosome;GO:0022625//cytosolic large ribosomal subunit",7299419,492.7,{"v":5.5e-139,"d":"5.50E-139"},"KOG0746","60S ribosomal protein L3 and related proteins",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K02925|1|7.2e-158|560.8|isc:IscW_ISCW023076|large subunit ribosomal protein L3e","JAW03689.1","17679.8090154742;","37708.0562458736;",0.468860259,"NA","NA","Down","Ribosomal protein L3, partial [Ornithodoros moubata]"]
["JAV99376.1",11.19090056,10.43824151,"GO:0060215//primitive hemopoiesis;GO:0030154//cell differentiation;GO:0051260//protein homooligomerization;GO:0007283//spermatogenesis;GO:0001878//response to yeast;GO:0006351//transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006334//nucleosome assembly","GO:0042393//histone binding;GO:0030332//cyclin binding","GO:0005737//cytoplasm;GO:0005634//nucleus","Hs4758756",437.2,{"v":2.9e-122,"d":"2.90E-122"},"KOG1507","Nucleosome assembly protein NAP-1",null,"BD","Chromatin structure and dynamics;Cell cycle control, cell division, chromosome partitioning","INFORMATION STORAGE AND PROCESSING;CELLULAR PROCESSES AND SIGNALING","K11279|1|1.3e-157|560.1|isc:IscW_ISCW005016|nucleosome assembly protein 1-like 1","JAV99376.1","34140.5638421573;","72468.0143078752;",0.471112175,"NA","NA","Down","Nucleosome assembly protein NAP-1, partial [Ornithodoros moubata]"]
["JAW05386.1",10.76858435,10.02229859,"GO:0016192//vesicle-mediated transport;GO:0006906//vesicle fusion;GO:0048278//vesicle docking;GO:0006886//intracellular protein transport","GO:0000149//SNARE binding;GO:0005484//SNAP receptor activity","GO:0031201//SNARE complex;GO:0012505//endomembrane system;GO:0016021//integral component of membrane","Hs20533698",138.7,{"v":1e-32,"d":"1.00E-32"},"KOG0811","SNARE protein PEP12/VAM3/Syntaxin 7/Syntaxin 17",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K13813|1|5.5e-37|158.3|tut:107366805|syntaxin 12/13!K08488|3|6.1e-36|154.8|zne:110835817|syntaxin 7","JAW05386.1","22523.1418426176;","47504.7199638847;",0.474124295,"NA","NA","Down","Syntaxin-7, partial [Ornithodoros moubata]"]
["JAW02004.1",10.14095287,9.399488664,"GO:0006839//mitochondrial transport;GO:0006810//transport","GO:0015367//oxoglutarate:malate antiporter activity","GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane","Hs21361114",438,{"v":1.3e-122,"d":"1.30E-122"},"KOG0759","Mitochondrial oxoglutarate/malate carrier proteins",null,"C","Energy production and conversion","METABOLISM","K15104|1|9.0e-132|473.8|dpte:113799605|solute carrier family 25 (mitochondrial oxoglutarate transporter), member 11","JAW02004.1","12082.2010893414;","25360.6203337923;",0.476415834,"NA","NA","Down","Lupus la ribonucleoprotein, partial [Ornithodoros moubata]"]
["XP_064480993.1",10.25402738,9.513053386,"GO:0009061//anaerobic respiration;GO:0006121//mitochondrial electron transport, succinate to ubiquinone;GO:0006105//succinate metabolic process;GO:0006099//tricarboxylic acid cycle;GO:0022900//electron transport chain;GO:0022904//respiratory electron transport chain","GO:0050660//flavin adenine dinucleotide binding;GO:0008177//succinate dehydrogenase (ubiquinone) activity;GO:0009055//electron transfer activity","GO:0005743//mitochondrial inner membrane;GO:0005749//mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)","Hs16157047",1011.1,{"v":8.2e-295,"d":"8.20E-295"},"KOG2403","Succinate dehydrogenase, flavoprotein subunit",null,"C","Energy production and conversion","METABOLISM","K00234|1|0.0e+00|1075.1|isc:IscW_ISCW000555|succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1]","XP_064480993.1","13535.2596587844;","28396.6761795288;",0.476649435,"NA","NA","Down","succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial-like [Ornithodoros turicata]"]
["JAV99648.1",11.06402555,10.34972793,"GO:0042402//cellular biogenic amine catabolic process","GO:0016491//oxidoreductase activity;GO:0008131//primary amine oxidase activity","GO:0016021//integral component of membrane","Hs4505093",384.4,{"v":2.5e-106,"d":"2.50E-106"},"KOG0029","Amine oxidase",null,"Q","Secondary metabolites biosynthesis, transport and catabolism","METABOLISM","K00274|1|3.6e-108|396.0|fab:101808185|monoamine oxidase [EC:1.4.3.4]","JAV99648.1","31248.5398152804;","63832.9983310402;",0.48953583,"NA","NA","Down","Uncharacterized protein, partial [Ornithodoros moubata]"]
["XP_064476948.1",12.75740939,12.05003303,{"$nulls":3},"CE26647",1001.5,{"v":1.1e-291,"d":"1.10E-291"},"KOG3681","Alpha-catenin",null,"W","Extracellular structures","CELLULAR PROCESSES AND SIGNALING","K05700|1|0.0e+00|1315.1|mdl:103573814|vinculin","XP_064476948.1","171105.060116048;","347114.29696835;",0.49293579,"NA","NA","Down","vinculin-like isoform X2 [Ornithodoros turicata]"]
["XP_064460167.1",10.42223106,9.725291704,"GO:0007030//Golgi organization;GO:0000278//mitotic cell cycle;GO:0008283//cell proliferation","GO:0003924//GTPase activity;GO:0016779//nucleotidyltransferase activity;GO:0003746//translation elongation factor activity;GO:0005525//GTP binding","GO:0005739//mitochondrion;GO:0005622//intracellular",7303306,629,{"v":6.3e-180,"d":"6.30E-180"},"KOG0460","Mitochondrial translation elongation factor Tu",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K02358|1|9.2e-211|736.9|isc:IscW_ISCW010766|elongation factor Tu","XP_064460167.1","16735.5705108614;","33598.3103208257;",0.498107505,"NA","NA","Down","elongation factor Tu, mitochondrial-like [Ornithodoros turicata]"]
["XP_064490068.1",10.78542499,10.1009967,{"$nulls":3},"Hs5803181",431.8,{"v":1e-120,"d":"1.00E-120"},"KOG0548","Molecular co-chaperone STI1",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K09553|1|1.2e-132|476.9|tut:107368957|stress-induced-phosphoprotein 1","XP_064490068.1","24367.2842703144;","48311.5040347797;",0.504378507,"NA","NA","Non","stress-induced-phosphoprotein 1-like [Ornithodoros turicata]"]
["JAV99232.1",13.52783633,12.84463793,"GO:0045454//cell redox homeostasis","GO:0004791//thioredoxin-disulfide reductase activity","GO:0005737//cytoplasm;GO:0005623//cell","CE13792",147.9,{"v":1.3e-35,"d":"1.30E-35"},"KOG2501","Thioredoxin, nucleoredoxin and related proteins",null,"R","General function prediction only","POORLY CHARACTERIZED","K17609|1|4.2e-53|211.5|isc:IscW_ISCW020655|nucleoredoxin [EC:1.8.1.8]","JAV99232.1","378752.385245811;","750005.883650081;",0.504999219,"NA","NA","Non","Nucleoredoxin-like protein 2 Thioredoxin, partial [Ornithodoros moubata]"]
["JAW05684.1",11.05435718,10.38199326,null,"GO:0004032//alditol:NADP+ 1-oxidoreductase activity;GO:0016491//oxidoreductase activity","GO:0005654//nucleoplasm;GO:0005829//cytosol",7294702,371.7,{"v":1.2e-102,"d":"1.20E-102"},"KOG1577","Aldo/keto reductase family proteins",null,"R","General function prediction only","POORLY CHARACTERIZED","K00011|1|3.8e-131|471.9|isc:IscW_ISCW002128|aldehyde reductase [EC:1.1.1.21]","JAW05684.1","32273.2265009454;","63218.8112094001;",0.51050037,"NA","NA","Non","Aldo-keto reductase, partial [Ornithodoros moubata]"]
["JAV99324.1",11.8447383,11.17390172,"GO:0040011//locomotion;GO:0030836//positive regulation of actin filament depolymerization;GO:0045214//sarcomere organization;GO:0030042//actin filament depolymerization","GO:0051015//actin filament binding","GO:0030864//cortical actin cytoskeleton;GO:0042643//actomyosin, actin portion",7294479,796.2,{"v":3.8e-230,"d":"3.80E-230"},"KOG0318","WD40 repeat stress protein/actin interacting protein",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K16482|1|2.5e-19|101.3|aga:AgaP_AGAP012029|centriolar protein POC1!K14855|3|1.3e-18|99.0|nvl:108566458|ribosome assembly protein 4","JAV99324.1","71246.5533362392;","139349.200575944;",0.511280675,"NA","NA","Non","Actin-interacting protein 1, partial [Ornithodoros moubata]"]
["JAW06759.1",10.91319935,10.2469948,"GO:0006094//gluconeogenesis","GO:0004613//phosphoenolpyruvate carboxykinase (GTP) activity;GO:0016301//kinase activity;GO:0005525//GTP binding",null,"Hs13653992",573.5,{"v":2.6e-163,"d":"2.60E-163"},"KOG3749","Phosphoenolpyruvate carboxykinase",null,"C","Energy production and conversion","METABOLISM","K01596|1|3.0e-170|602.1|lak:106169200|phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]","JAW06759.1","28197.6746718004;","54896.1965833252;",0.513654432,"NA","NA","Non","Phosphoenolpyruvate carboxykinase, partial [Ornithodoros moubata]"]
["XP_064455552.1",13.39527503,12.73807083,"GO:0042989//sequestering of actin monomers","GO:0003779//actin binding;GO:0003785//actin monomer binding","GO:0005856//cytoskeleton;GO:0015629//actin cytoskeleton;GO:0005938//cell cortex","At5g56600",75.1,{"v":9.8e-14,"d":"9.80E-14"},"KOG1755","Profilin",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K05759|1|1.6e-51|206.1|tut:107368551|profilin","XP_064455552.1","340466.097620963;","656892.082986633;",0.518298373,"NA","NA","Non","profilin-like [Ornithodoros turicata]"]
["XP_064490160.1",10.44406277,9.789320227,{"$nulls":13},"XP_064490160.1","17842.1734100796;","34339.8844010281;",0.519575815,"NA","NA","Non","uncharacterized protein LOC135401589 [Ornithodoros turicata]"]
["JAV99828.1",11.61969661,10.97166841,null,"GO:0016787//hydrolase activity;GO:0005524//ATP binding",null,"Hs6005942",1385.2,0,"KOG0730","AAA+-type ATPase",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K13525|1|0.0e+00|1429.1|tut:107360392|transitional endoplasmic reticulum ATPase","JAV99828.1","58201.616532773;","111267.958769998;",0.523076159,"NA","NA","Non","AAA family ATPase, partial [Ornithodoros moubata]"]
["JAW02925.1",13.36739433,12.71961948,"GO:0006096//glycolytic process","GO:0000287//magnesium ion binding;GO:0004634//phosphopyruvate hydratase activity","GO:0000015//phosphopyruvate hydratase complex",7296048,668.7,{"v":6.6e-192,"d":"6.60E-192"},"KOG2670","Enolase",null,"G","Carbohydrate transport and metabolism","METABOLISM","K01689|1|6.0e-196|687.6|aga:AgaP_AGAP007827|enolase [EC:4.2.1.11]","JAW02925.1","334241.639816924;","638830.432076182;",0.5232087,"NA","NA","Non","Polyglutamine binding protein, partial [Ornithodoros moubata]"]
["JAW03013.1",10.000108,9.378864821,"GO:0035206//regulation of hemocyte proliferation;GO:0045610//regulation of hemocyte differentiation","GO:0020037//heme binding;GO:0009703//nitrate reductase (NADH) activity;GO:0046872//metal ion binding","GO:0016021//integral component of membrane;GO:0012505//endomembrane system",7304197,154.1,{"v":1.7e-37,"d":"1.70E-37"},"KOG0537","Cytochrome b5",null,"C","Energy production and conversion","METABOLISM","K17418|1|1.0e-24|117.1|shx:MS3_03488|large subunit ribosomal protein L37!K14327|3|3.0e-13|79.0|tut:107360811|regulator of nonsense transcripts 2!K10595|4|5.7e-12|74.7|bfo:BRAFLDRAFT_73255|E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]","JAW03013.1","11835.5716291813;","22028.8447628217;",0.537276092,"NA","NA","Non","Protein XAP-5, partial [Ornithodoros moubata]"]
["XP_064458375.1",13.1419633,12.5227121,null,"GO:0004725//protein tyrosine phosphatase activity;GO:0005509//calcium ion binding",null,7292157,3641.7,0,"KOG0040","Ca2+-binding actin-bundling protein (spectrin), alpha chain (EF-Hand protein superfamily)",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K06114|1|0.0e+00|4279.9|isc:IscW_ISCW000012|spectrin alpha","XP_064458375.1","274501.525223152;","509896.631874124;",0.538347398,"NA","NA","Non","spectrin alpha chain-like isoform X1 [Ornithodoros turicata]"]
["JAW03032.1",12.98695471,12.37303302,"GO:0006006//glucose metabolic process;GO:0006096//glycolytic process","GO:0051287//NAD binding;GO:0004365//glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity;GO:0050661//NADP binding",null,7293147,517.7,{"v":1.5e-146,"d":"1.50E-146"},"KOG0657","Glyceraldehyde 3-phosphate dehydrogenase",null,"G","Carbohydrate transport and metabolism","METABOLISM","K00134|1|2.2e-174|615.5|isc:IscW_ISCW018700|glyceraldehyde 3-phosphate dehydrogenase [EC:1.2.1.12]","JAW03032.1","236341.488393386;","436679.460928989;",0.541224192,"NA","NA","Non","Asparaginase, partial [Ornithodoros moubata]"]
["JAV99427.1",12.7707759,12.16383288,"GO:0046034//ATP metabolic process;GO:0015991//ATP hydrolysis coupled proton transport","GO:0005524//ATP binding","GO:0033180//proton-transporting V-type ATPase, V1 domain",7299652,903.7,{"v":1.4e-262,"d":"1.40E-262"},"KOG1351","Vacuolar H+-ATPase V1 sector, subunit B",null,"C","Energy production and conversion","METABOLISM","K02147|1|5.0e-263|910.6|cqu:CpipJ_CPIJ003418|V-type H+-transporting ATPase subunit B","JAV99427.1","191727.980689432;","351785.152115637;",0.54501442,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW03206.1",14.18268036,13.58313637,null,"GO:0003960//NADPH:quinone reductase activity;GO:0016491//oxidoreductase activity",null,"Hs14776255",449.9,{"v":4.7e-126,"d":"4.70E-126"},"KOG1198","Zinc-binding oxidoreductase",null,"CR","Energy production and conversion;General function prediction only","METABOLISM;POORLY CHARACTERIZED","K10133|1|2.0e-31|141.0|cjo:107312279|tumor protein p53-inducible protein 3 [EC:1.-.-.-]","JAW03206.1","792649.468564432;","1443643.03813631;",0.549061955,"NA","NA","Non","RNA-directed DNA polymerase from transposon X-element, partial [Ornithodoros moubata]"]
["JAW02482.1",14.03034536,13.43599273,null,"GO:0051015//actin filament binding",null,"Hs6005944",404.8,{"v":2.5e-112,"d":"2.50E-112"},"KOG0443","Actin regulatory proteins (gelsolin/villin family)",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K05768|1|2.5e-285|984.9|isc:IscW_ISCW007199|gelsolin","JAW02482.1","684191.227394042;","1239657.08818126;",0.551919748,"NA","NA","Non","Zinc finger protein, partial [Ornithodoros moubata]"]
["JAW05147.1",9.719787811,9.126816541,{"$nulls":3},7303255,171,{"v":6.3e-42,"d":"6.30E-42"},"KOG0516","Dystonin, GAS (Growth-arrest-specific protein), and related proteins",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K10382|1|6.4e-74|282.7|fcd:110844801|dystonin","JAW05147.1","9198.69165096998;","16643.7127407385;",0.552682673,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW04877.1",10.84489489,10.26008053,"GO:0006613//cotranslational protein targeting to membrane",null,"GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane","Hs4507237",90.5,{"v":3e-18,"d":"3.00E-18"},"KOG1631","Translocon-associated complex TRAP, alpha subunit",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K13249|1|7.1e-23|111.3|sko:100371575|translocon-associated protein subunit alpha","JAW04877.1","28569.0868945414;","51271.7343099434;",0.557209294,"NA","NA","Non","Signal sequence receptor, partial [Ornithodoros moubata]"]
["JAV99049.1",9.199609552,8.629307538,"GO:0008152//metabolic process","GO:0004165//dodecenoyl-CoA delta-isomerase activity;GO:0004402//histone acetyltransferase activity;GO:0000062//fatty-acyl-CoA binding;GO:0016853//isomerase activity",null,"Hs5174625_2",248.4,{"v":1.9e-65,"d":"1.90E-65"},"KOG0016","Enoyl-CoA hydratase/isomerase",null,"I","Lipid transport and metabolism","METABOLISM","K13239|1|1.8e-119|433.3|isc:IscW_ISCW017077|Delta3-Delta2-enoyl-CoA isomerase [EC:5.3.3.8]","JAV99049.1","5593.20382863001;","9893.26549492081;",0.565354668,"NA","NA","Non","Enoyl-CoA hydratase, partial [Ornithodoros moubata]"]
["JAR87693.1",11.23224308,10.66227906,{"$nulls":3},7292436,241.5,{"v":1.7e-63,"d":"1.70E-63"},"KOG2046","Calponin",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K20526|1|1.2e-88|330.5|isc:IscW_ISCW021202|transgelin","JAR87693.1","42713.8736477214;","75526.8178247836;",0.565545787,"NA","NA","Non","calponin transgelin, partial [Alectorobius mimon]"]
["XP_064484059.1",10.15979006,9.594983182,null,"GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0008234//cysteine-type peptidase activity",null,7296777,340.5,{"v":4.5e-93,"d":"4.50E-93"},"KOG1542","Cysteine proteinase Cathepsin F",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K01373|1|3.9e-116|422.5|fcd:110859207|cathepsin F [EC:3.4.22.41]","XP_064484059.1","14690.8948435344;","25842.8709626355;",0.568469922,"NA","NA","Non","cathepsin L-like [Ornithodoros turicata]"]
["JAV98918.1",15.19391354,14.63999557,"GO:0006749//glutathione metabolic process","GO:0016740//transferase activity;GO:0004364//glutathione transferase activity","GO:0005737//cytoplasm",7299601,147.1,{"v":3.3999999999999997e-35,"d":"3.40E-35"},"KOG0867","Glutathione S-transferase",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K00799|1|6.1e-64|248.1|isc:IscW_ISCW005803|glutathione S-transferase [EC:2.5.1.18]","JAV98918.1","2280705.93283018;","3968558.71264133;",0.574693761,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAV99483.1",13.73170769,13.18260407,"GO:0030042//actin filament depolymerization","GO:0003779//actin binding","GO:0015629//actin cytoskeleton",7291724,169.9,{"v":3.3e-42,"d":"3.30E-42"},"KOG1735","Actin depolymerizing factor",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K21286|1|3.2e-64|248.4|dpte:113789234|protein N-terminal glutamine amidohydrolase [EC:3.5.1.122]!K05765|2|1.0e-62|243.4|isc:IscW_ISCW006326|cofilin","JAV99483.1","531046.07689465;","919612.519907411;",0.577467211,"NA","NA","Non","Cofilin, partial [Ornithodoros moubata]"]
["JAW00020.1",10.84914507,10.30072164,"GO:0019853//L-ascorbic acid biosynthetic process","GO:0030234//enzyme regulator activity;GO:0004341//gluconolactonase activity;GO:0005509//calcium ion binding","GO:0005576//extracellular region","Hs4759036",170.2,{"v":5.1e-42,"d":"5.10E-42"},"KOG4499","Ca2+-binding protein Regucalcin/SMP30",null,"PT","Inorganic ion transport and metabolism;Signal transduction mechanisms","METABOLISM;CELLULAR PROCESSES AND SIGNALING","K01053|1|2.9e-56|223.0|isc:IscW_ISCW010163|gluconolactonase [EC:3.1.1.17]","JAW00020.1","29754.0827293105;","51490.1119531932;",0.577860129,"NA","NA","Non","Senescence marker protein-30, partial [Ornithodoros moubata]"]
["XP_064461250.1",9.694037692,9.147100956,"GO:0050832//defense response to fungus;GO:0007527//adult somatic muscle development",null,null,7302313,615.9,{"v":6.6e-176,"d":"6.60E-176"},"KOG0303","Actin-binding protein Coronin, contains WD40 repeats",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K13886|1|7.2e-194|681.0|tut:107360371|coronin-1B/1C/6","XP_064461250.1","9387.18702409231;","16220.6060569421;",0.57871987,"NA","NA","Non","coronin-1C-like [Ornithodoros turicata] >XP_064461251.1 coronin-1C-like [Ornithodoros turicata]"]
["JAW06300.1",12.79563989,12.25029026,"GO:0009086//methionine biosynthetic process","GO:0047150//betaine-homocysteine S-methyltransferase activity;GO:0008270//zinc ion binding","GO:0005737//cytoplasm","Hs4502407",561.6,{"v":1e-159,"d":"1.00E-159"},"KOG1579","Homocysteine S-methyltransferase",null,"E","Amino acid transport and metabolism","METABOLISM","K00544|1|9.7e-169|597.0|bfo:BRAFLDRAFT_78594|betaine-homocysteine S-methyltransferase [EC:2.1.1.5]","JAW06300.1","209041.956005669;","360641.578758545;",0.579639089,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW03005.1",9.855083023,9.311184094,"GO:0005975//carbohydrate metabolic process;GO:0005980//glycogen catabolic process","GO:0102250//linear malto-oligosaccharide phosphorylase activity;GO:0030170//pyridoxal phosphate binding;GO:0008184//glycogen phosphorylase activity;GO:0102499//SHG alpha-glucan phosphorylase activity","GO:0005737//cytoplasm",7296006,806.2,{"v":3.4e-233,"d":"3.40E-233"},"KOG2099","Glycogen phosphorylase",null,"G","Carbohydrate transport and metabolism","METABOLISM","K00688|1|1.0e-269|932.9|isc:IscW_ISCW000885|glycogen phosphorylase [EC:2.4.1.1]","JAW03005.1","11061.0376816786;","19054.9658849549;",0.580480582,"NA","NA","Non","Sulfotransferase, partial [Ornithodoros moubata]"]
["JAW05841.1",11.21957355,10.67789745,{"$nulls":3},"Hs4503057",75.9,{"v":6.1e-14,"d":"6.10E-14"},"KOG3591","Alpha crystallins",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K09542|1|1.6e-41|172.9|isc:IscW_ISCW024717|crystallin, alpha B","JAW05841.1","43386.2325331578;","74575.9651698002;",0.581772323,"NA","NA","Non","Alpha crystallin, partial [Ornithodoros moubata]"]
["JAW03015.1",14.00764143,13.47376326,"GO:0006950//response to stress;GO:0006457//protein folding","GO:0051082//unfolded protein binding;GO:0005524//ATP binding",null,"Hs13129150",1209.1,0,"KOG0019","Molecular chaperone (HSP90 family)",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K04079|1|0.0e+00|1231.5|zne:110837294|molecular chaperone HtpG","JAW03015.1","710527.730461135;","1211829.10378102;",0.586326676,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW06799.1",11.94511296,11.41136572,"GO:0006434//seryl-tRNA aminoacylation","GO:0004828//serine-tRNA ligase activity;GO:0005524//ATP binding","GO:0005737//cytoplasm",7295855,701.8,{"v":8.2e-202,"d":"8.20E-202"},"KOG2509","Seryl-tRNA synthetase",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K01875|1|2.1e-213|745.7|tca:656867|seryl-tRNA synthetase [EC:6.1.1.11]","JAW06799.1","90342.7201086327;","154062.394289898;",0.586403454,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["XP_064470971.1",10.01771337,9.486121283,"GO:0006486//protein glycosylation;GO:0043687//post-translational protein modification;GO:0018279//protein N-linked glycosylation via asparagine","GO:0004576//oligosaccharyl transferase activity;GO:0004579//dolichyl-diphosphooligosaccharide-protein glycotransferase activity","GO:0016021//integral component of membrane;GO:0008250//oligosaccharyltransferase complex","Hs22042731",1194.1,0,"KOG2292","Oligosaccharyltransferase, STT3 subunit",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K07151|1|0.0e+00|1238.0|tut:107362347|dolichyl-diphosphooligosaccharide---protein glycosyltransferase [EC:2.4.99.18]","XP_064470971.1","13175.591696051;","22420.1047069775;",0.587668607,"NA","NA","Non","dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B-like [Ornithodoros turicata]"]
["JAW03009.1",11.33744696,10.80929487,"GO:0071542//dopaminergic neuron differentiation;GO:0070050//neuron cellular homeostasis;GO:0042417//dopamine metabolic process;GO:0001963//synaptic transmission, dopaminergic;GO:0031175//neuron projection development","GO:0005509//calcium ion binding","GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005783//endoplasmic reticulum",7300136,201.4,{"v":1.2e-51,"d":"1.20E-51"},"KOG4154","Arginine-rich protein",null,"R","General function prediction only","POORLY CHARACTERIZED","K22556|1|7.1e-63|244.2|isc:IscW_ISCW006484|mesencephalic astrocyte-derived neurotrophic factor","JAW03009.1","49478.5674121117;","83905.5433730825;",0.589693665,"NA","NA","Non","AGAP005213-PA, partial [Ornithodoros moubata]"]
["JAW03960.1",9.007376537,8.481471089,"GO:0007005//mitochondrion organization",null,"GO:0031305//integral component of mitochondrial inner membrane",{"$nulls":10},"JAW03960.1","4824.54201113114;","8163.07762558973;",0.591019984,"NA","NA","Non","Transmembrane protein, partial [Ornithodoros moubata]"]
["JAW06070.1",10.22173588,9.697758218,"GO:0008152//metabolic process","GO:0033814//propanoyl-CoA C-acyltransferase activity;GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups",null,"7298493_1",556.2,{"v":4.5e-158,"d":"4.50E-158"},"KOG1406","Peroxisomal 3-ketoacyl-CoA-thiolase P-44/SCP2",null,"I","Lipid transport and metabolism","METABOLISM","K08764|1|4.5e-201|704.5|isc:IscW_ISCW022661|sterol carrier protein 2 [EC:2.3.1.176]","JAW06070.1","16281.0676485665;","27494.351889712;",0.592160445,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW06800.1",9.373691277,8.85891832,"GO:0034975//protein folding in endoplasmic reticulum",null,"GO:0072546//ER membrane protein complex","Hs20470446",456.1,{"v":1.4e-127,"d":"1.40E-127"},"KOG2103","Uncharacterized conserved protein",null,"S","Function unknown","POORLY CHARACTERIZED",null,"JAW06800.1","7036.86699006695;","11774.497900833;",0.597636269,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW03764.1",11.87105193,11.35707459,"GO:0006452//translational frameshifting;GO:0045901//positive regulation of translational elongation;GO:0045905//positive regulation of translational termination","GO:0003746//translation elongation factor activity;GO:0043022//ribosome binding;GO:0003743//translation initiation factor activity",null,7291729,209.5,{"v":4e-54,"d":"4.00E-54"},"KOG3271","Translation initiation factor 5A (eIF-5A)",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K03263|1|8.2e-71|270.4|isc:IscW_ISCW020373|translation initiation factor 5A","JAW03764.1","85568.6784155343;","143064.653534013;",0.598111947,"NA","NA","Non","Eukaryotic translation initiation factor 5A eIF-5A, partial [Ornithodoros moubata]"]
["JAR87650.1",10.57941418,10.06977686,"GO:0006099//tricarboxylic acid cycle","GO:0003994//aconitate hydratase activity;GO:0046872//metal ion binding;GO:0051539//4 iron, 4 sulfur cluster binding","GO:0005739//mitochondrion","Hs4501867",741.5,{"v":9e-214,"d":"9.00E-214"},"KOG0453","Aconitase/homoaconitase (aconitase superfamily)",null,"CE","Energy production and conversion;Amino acid transport and metabolism","METABOLISM;METABOLISM","K01681|1|1.2e-229|799.7|dpte:113798854|aconitate hydratase [EC:4.2.1.3]","JAR87650.1","23618.2940883283;","39317.0748534293;",0.60071341,"NA","NA","Non","aconitate mitochondrial like, partial [Alectorobius mimon]"]
["XP_064481408.1",13.23704904,12.73071372,"GO:0007015//actin filament organization","GO:0003785//actin monomer binding",null,7290465,134.8,{"v":1e-31,"d":"1.00E-31"},"KOG4794","Thymosin beta",null,"N","Cell motility","CELLULAR PROCESSES AND SIGNALING",null,"XP_064481408.1","337970.442369344;","560760.424614386;",0.60270024,"NA","NA","Non","thymosin beta-like isoform X1 [Ornithodoros turicata] >XP_064481409.1 thymosin beta-like isoform X1 [Ornithodoros turicata]"]
["JAW03640.1",9.957494507,9.45392033,{"$nulls":3},7298932,238.8,{"v":7e-63,"d":"7.00E-63"},"KOG3346","Phosphatidylethanolamine binding protein",null,"R","General function prediction only","POORLY CHARACTERIZED","K12367|1|4.8e-59|231.5|tsp:Tsp_02455|dedicator of cytokinesis protein 2!K17439|2|2.7e-49|199.1|acs:100555543|large subunit ribosomal protein L35","JAW03640.1","12758.08325278;","21109.8388474788;",0.604366682,"NA","NA","Non","AAEL012666-PA, partial [Ornithodoros moubata]"]
["XP_064477708.1",9.256486048,8.754239065,null,"GO:0015293//symporter activity","GO:0016021//integral component of membrane","Hs18252049",461.5,{"v":1.9e-129,"d":"1.90E-129"},"KOG3787","Glutamate/aspartate and neutral amino acid transporters",null,"E","Amino acid transport and metabolism","METABOLISM","K05614|1|2.4e-132|476.5|srx:107743401|solute carrier family 1 (glial high affinity glutamate transporter), member 3","XP_064477708.1","6337.49630661305;","10472.269551815;",0.605169326,"NA","NA","Non","excitatory amino acid transporter 3-like isoform X3 [Ornithodoros turicata] >XP_064477709.1 excitatory amino acid transporter 3-like isoform X3 [Ornithodoros turicata] >XP_064477710.1 excitatory amino acid transporter 3-like isoform X3 [Ornithodoros turicata] >XP_064477711.1 excitatory amino acid transporter 3-like isoform X3 [Ornithodoros turicata]"]
["XP_064467924.1",11.1996306,10.70209972,"GO:0006342//chromatin silencing","GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity","GO:0005634//nucleus;GO:0000786//nucleosome;GO:0000790//nuclear chromatin","Hs20555882",219.5,{"v":3.1e-57,"d":"3.10E-57"},"KOG1756","Histone 2A",null,"B","Chromatin structure and dynamics","INFORMATION STORAGE AND PROCESSING","K11251|1|8.0e-61|236.9|isc:IscW_ISCW019497|histone H2A","XP_064467924.1","44449.0880638476;","73103.4325892756;",0.608030109,"NA","NA","Non","histone H2A-like [Ornithodoros turicata]"]
["JAW02238.1",10.43461178,9.938023344,"GO:0006090//pyruvate metabolic process;GO:0006094//gluconeogenesis","GO:0046872//metal ion binding;GO:0004736//pyruvate carboxylase activity;GO:0009374//biotin binding;GO:0004075//biotin carboxylase activity;GO:0005524//ATP binding",null,7303838,998.4,{"v":5.7e-291,"d":"5.70E-291"},"KOG0369","Pyruvate carboxylase",null,"C","Energy production and conversion","METABOLISM","K01958|1|2.0e-299|1031.9|dpx:DAPPUDRAFT_70042|pyruvate carboxylase [EC:6.4.1.1]","JAW02238.1","20702.7815414362;","34016.8674703878;",0.60860341,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW01514.1",11.1370112,10.64578412,"GO:0007160//cell-matrix adhesion",{"$nulls":12},"JAW01514.1","42015.0901772679;","68666.120199353;",0.611875115,"NA","NA","Non","Molecular chaperone, partial [Ornithodoros moubata]"]
["XP_064461101.1",11.79769058,11.30863778,"GO:0007165//signal transduction","GO:0004402//histone acetyltransferase activity",null,"CE02186",651,{"v":1.1e-186,"d":"1.10E-186"},"KOG0286","G-protein beta subunit",null,"R","General function prediction only","POORLY CHARACTERIZED","K04536|1|7.7e-199|696.8|isc:IscW_ISCW009711|guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1","XP_064461101.1","81522.7808429085;","132944.972885361;",0.613206946,"NA","NA","Non","guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 [Ornithodoros turicata] >XP_064461102.1 guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 [Ornithodoros turicata]"]
["XP_064484434.1",12.04676545,11.56243817,null,"GO:0003779//actin binding;GO:0005509//calcium ion binding",null,7290243,1528.8,0,"KOG0035","Ca2+-binding actin-bundling protein (actinin), alpha chain (EF-Hand protein superfamily)",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K05699|1|0.0e+00|1573.5|tut:107360403|actinin alpha 1/4","XP_064484434.1","105075.894288195;","170546.873332433;",0.616111525,"NA","NA","Non","alpha-actinin isoform X2 [Ornithodoros turicata]"]
["JAV99538.1",9.512340473,9.02831263,"GO:0007420//brain development;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:1904888//cranial skeletal system development;GO:0001822//kidney development",null,"GO:0005737//cytoplasm;GO:0031595//nuclear proteasome complex;GO:0000502//proteasome complex;GO:0008541//proteasome regulatory particle, lid subcomplex","Hs4506221",575.9,{"v":6.4e-164,"d":"6.40E-164"},"KOG1498","26S proteasome regulatory complex, subunit RPN5/PSMD12",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K03035|1|4.7e-178|628.2|zne:110830288|26S proteasome regulatory subunit N5","JAV99538.1","8335.78214690995;","13525.6136276422;",0.616296042,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW03780.1",11.37115872,10.88838769,"GO:0018105//peptidyl-serine phosphorylation;GO:0016334//establishment or maintenance of polarity of follicular epithelium;GO:0034332//adherens junction organization;GO:0035152//regulation of tube architecture, open tracheal system;GO:0046777//protein autophosphorylation;GO:0006228//UTP biosynthetic process;GO:0006241//CTP biosynthetic process;GO:0006468//protein phosphorylation;GO:0000278//mitotic cell cycle;GO:0009117//nucleotide metabolic process;GO:0006183//GTP biosynthetic process;GO:0007424//open tracheal system development;GO:0007427//epithelial cell migration, open tracheal system;GO:0007017//microtubule-based process;GO:0006165//nucleoside diphosphate phosphorylation","GO:0000287//magnesium ion binding;GO:0005524//ATP binding;GO:0005525//GTP binding;GO:0008017//microtubule binding;GO:0016301//kinase activity;GO:0004550//nucleoside diphosphate kinase activity","GO:0005874//microtubule;GO:0005737//cytoplasm;GO:0005880//nuclear microtubule;GO:0005886//plasma membrane;GO:0005622//intracellular",7302087,228.4,{"v":9.6e-60,"d":"9.60E-60"},"KOG0888","Nucleoside diphosphate kinase",null,"F","Nucleotide transport and metabolism","METABOLISM","K00940|1|8.6e-64|247.3|isc:IscW_ISCW023074|nucleoside-diphosphate kinase [EC:2.7.4.6]","JAW03780.1","53550.8895697547;","86782.3655206161;",0.617071098,"NA","NA","Non","Nucleoside diphosphate kinase, partial [Ornithodoros moubata]"]
["JAW01754.1",10.29319674,9.816142193,"GO:0007016//cytoskeletal anchoring at plasma membrane;GO:0007155//cell adhesion","GO:0005200//structural constituent of cytoskeleton;GO:0005158//insulin receptor binding;GO:0051015//actin filament binding","GO:0005856//cytoskeleton;GO:0001726//ruffle;GO:0005925//focal adhesion","Hs22035665",219.9,{"v":5.1e-57,"d":"5.10E-57"},"KOG4261","Talin",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K06271|1|8.2e-103|377.5|isc:IscW_ISCW023338|talin","JAW01754.1","18327.2113483944;","29531.0267152985;",0.620608675,"NA","NA","Non","Alpha-1 4 glucan phosphorylase, partial [Ornithodoros moubata]"]
["JAV99228.1",11.68894659,11.21258181,"GO:0006457//protein folding;GO:0006458//'de novo' protein folding;GO:0061077//chaperone-mediated protein folding","GO:0044183//protein binding involved in protein folding;GO:0051082//unfolded protein binding;GO:0005524//ATP binding","GO:0005737//cytoplasm;GO:0005832//chaperonin-containing T-complex","Hs6005727",697.6,{"v":1.7e-200,"d":"1.70E-200"},"KOG0362","Chaperonin complex component, TCP-1 theta subunit (CCT8)",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K09500|1|3.4e-212|741.9|isc:IscW_ISCW012934|T-complex protein 1 subunit theta","JAV99228.1","74056.3675430628;","119246.325305672;",0.621036894,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW02966.1",13.49384134,13.05272294,"GO:0006508//proteolysis;GO:0030163//protein catabolic process","GO:0004190//aspartic-type endopeptidase activity",null,7304149,469.5,{"v":5.3e-132,"d":"5.30E-132"},"KOG1339","Aspartyl protease",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K01379|1|2.5e-137|492.7|isc:IscW_ISCW003823|cathepsin D [EC:3.4.23.5]","JAW02966.1","466364.564902672;","724937.9500187;",0.643316528,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW00846.1",12.71815897,12.27942706,"GO:0031115//negative regulation of microtubule polymerization;GO:1902669//positive regulation of axon guidance;GO:0007017//microtubule-based process;GO:0001764//neuron migration","GO:0005200//structural constituent of cytoskeleton;GO:0003924//GTPase activity;GO:0005509//calcium ion binding;GO:0046982//protein heterodimerization activity;GO:0005525//GTP binding","GO:0005737//cytoplasm;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005874//microtubule;GO:0015630//microtubule cytoskeleton","Hs5174735",870.5,{"v":1.2e-252,"d":"1.20E-252"},"KOG1375","Beta tubulin",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K07375|1|6.2e-252|873.6|cfa:478702|tubulin beta","JAW00846.1","215222.37283468;","333753.831433415;",0.644853639,"NA","NA","Non","RNA helicase, partial [Ornithodoros moubata]"]
["JAW00028.1",10.1216321,9.684414883,"GO:0015986//ATP synthesis coupled proton transport;GO:0051881//regulation of mitochondrial membrane potential;GO:0099132//ATP hydrolysis coupled cation transmembrane transport;GO:0032007//negative regulation of TOR signaling;GO:0008340//determination of adult lifespan;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0006979//response to oxidative stress","GO:0016787//hydrolase activity;GO:0015078//hydrogen ion transmembrane transporter activity","GO:0000274//mitochondrial proton-transporting ATP synthase, stator stalk;GO:0000276//mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)",7300478,166,{"v":5.7e-41,"d":"5.70E-41"},"KOG3366","Mitochondrial F1F0-ATP synthase, subunit d/ATP7",null,"C","Energy production and conversion","METABOLISM","K02138|1|3.3e-44|182.2|isc:IscW_ISCW016217|F-type H+-transporting ATPase subunit d","JAW00028.1","16065.2668709264;","24875.3366821261;",0.645831133,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAV99939.1",10.69218756,10.26033743,"GO:0006457//protein folding;GO:0006458//'de novo' protein folding;GO:0061077//chaperone-mediated protein folding","GO:0044183//protein binding involved in protein folding;GO:0051082//unfolded protein binding;GO:0005524//ATP binding","GO:0005737//cytoplasm;GO:0005832//chaperonin-containing T-complex","Hs5453607",816.6,{"v":2.4e-236,"d":"2.40E-236"},"KOG0361","Chaperonin complex component, TCP-1 eta subunit (CCT7)",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K09499|1|4.2e-260|901.0|isc:IscW_ISCW023397|T-complex protein 1 subunit eta","JAV99939.1","28576.4270570462;","44010.6776718882;",0.649306681,"NA","NA","Non","T-complex protein 1 subunit, partial [Ornithodoros moubata]"]
["JAV99494.1",9.643610062,9.216539952,"GO:0008152//metabolic process;GO:0006635//fatty acid beta-oxidation","GO:0003824//catalytic activity;GO:0004300//enoyl-CoA hydratase activity","GO:0005739//mitochondrion","Hs4502327",305.1,{"v":1.3e-82,"d":"1.30E-82"},"KOG1679","Enoyl-CoA hydratase",null,"I","Lipid transport and metabolism","METABOLISM","K05607|1|4.9e-85|318.5|sgh:107558265|methylglutaconyl-CoA hydratase [EC:4.2.1.18]","JAV99494.1","10062.1883680304;","15422.9210545158;",0.652417809,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAV98722.1",9.166049931,8.743198495,{"$nulls":3},7301136,1298.9,0,"KOG0163","Myosin class VI heavy chain",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K10358|1|0.0e+00|1450.3|dpx:DAPPUDRAFT_228516|myosin VI","JAV98722.1","6267.91156606789;","9566.76058803416;",0.655175961,"NA","NA","Non","GA26528 isoform C, partial [Ornithodoros moubata]"]
["JAW02719.1",12.83035268,12.40961228,"GO:0051403//stress-activated MAPK cascade;GO:0006457//protein folding;GO:0030308//negative regulation of cell growth;GO:0071480//cellular response to gamma radiation;GO:0032387//negative regulation of intracellular transport;GO:0050821//protein stabilization;GO:0010629//negative regulation of gene expression;GO:0002088//lens development in camera-type eye;GO:0010941//regulation of cell death;GO:0007517//muscle organ development;GO:0001666//response to hypoxia;GO:1905907//negative regulation of amyloid fibril formation;GO:0051260//protein homooligomerization;GO:0007021//tubulin complex assembly;GO:0060561//apoptotic process involved in morphogenesis;GO:0032463//negative regulation of protein homooligomerization;GO:2000378//negative regulation of reactive oxygen species metabolic process;GO:0032355//response to estradiol;GO:0031109//microtubule polymerization or depolymerization;GO:0043066//negative regulation of apoptotic process;GO:0007568//aging;GO:0042542//response to hydrogen peroxide;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043010//camera-type eye development","GO:0032403//protein complex binding;GO:0046872//metal ion binding;GO:0042803//protein homodimerization activity;GO:0008017//microtubule binding;GO:0005212//structural constituent of eye lens;GO:0008092//cytoskeletal protein binding;GO:0051082//unfolded protein binding;GO:0042802//identical protein binding","GO:0032432//actin filament bundle;GO:0030424//axon;GO:0045202//synapse;GO:0030018//Z disc;GO:0005737//cytoplasm;GO:0043204//perikaryon;GO:0043209//myelin sheath;GO:0005634//nucleus;GO:0031674//I band;GO:0005739//mitochondrion;GO:0097060//synaptic membrane;GO:0009986//cell surface;GO:0005794//Golgi apparatus;GO:0015630//microtubule cytoskeleton;GO:0031430//M band;GO:0014069//postsynaptic density;GO:0005886//plasma membrane;GO:0070062//extracellular exosome;GO:0043197//dendritic spine;GO:0005829//cytosol;GO:0043292//contractile fiber;GO:0097512//cardiac myofibril","Hs4503057",115.2,{"v":1.1e-25,"d":"1.10E-25"},"KOG3591","Alpha crystallins",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K09542|1|8.9e-34|147.5|isc:IscW_ISCW002513|crystallin, alpha B","JAW02719.1","245146.747334101;","373380.274614782;",0.65656052,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["XP_064473180.1",8.997612894,8.576936165,{"$nulls":3},7298842,532.3,{"v":1.2e-150,"d":"1.20E-150"},"KOG0251","Clathrin assembly protein AP180 and related proteins, contain ENTH domain",null,"TU","Signal transduction mechanisms;Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING;CELLULAR PROCESSES AND SIGNALING","K20044|1|4.3e-185|652.1|nvi:100120513|phosphatidylinositol-binding clathrin assembly protein","XP_064473180.1","5307.81831044479;","8083.76407877054;",0.656602328,"NA","NA","Non","phosphatidylinositol-binding clathrin assembly protein LAP-like isoform X5 [Ornithodoros turicata]"]
["JAW02673.1",13.13095808,12.71265573,null,"GO:0004177//aminopeptidase activity;GO:0008235//metalloexopeptidase activity;GO:0030145//manganese ion binding","GO:0005737//cytoplasm",7299812,344.4,{"v":2.9e-94,"d":"2.90E-94"},"KOG2597","Predicted aminopeptidase of the M17 family",null,"R","General function prediction only","POORLY CHARACTERIZED","K01255|1|5.2e-139|498.4|isc:IscW_ISCW003100|leucyl aminopeptidase [EC:3.4.11.1]","JAW02673.1","331922.148465418;","504315.869879963;",0.658163203,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW03400.1",10.9555506,10.53964685,"GO:0005975//carbohydrate metabolic process","GO:0004567//beta-mannosidase activity;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds",null,"Hs5174523",680.2,{"v":4.7e-195,"d":"4.70E-195"},"KOG2230","Predicted beta-mannosidase",null,"G","Carbohydrate transport and metabolism","METABOLISM","K01192|1|8.4e-216|754.6|zne:110829033|beta-mannosidase [EC:3.2.1.25]","JAW03400.1","37784.2205095221;","57271.0534536665;",0.659743766,"NA","NA","Non","Beta-mannosidase, partial [Ornithodoros moubata]"]
["JAV99685.1",11.26181962,10.8539169,"GO:0001745//compound eye morphogenesis;GO:0048488//synaptic vesicle endocytosis;GO:1990386//mitotic cleavage furrow ingression;GO:1904801//positive regulation of neuron remodeling;GO:1902036//regulation of hematopoietic stem cell differentiation;GO:0043001//Golgi to plasma membrane protein transport;GO:0032011//ARF protein signal transduction;GO:0048749//compound eye development;GO:0007269//neurotransmitter secretion;GO:0007264//small GTPase mediated signal transduction;GO:0006892//post-Golgi vesicle-mediated transport;GO:0007112//male meiosis cytokinesis;GO:0010883//regulation of lipid storage;GO:0045807//positive regulation of endocytosis","GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0005795//Golgi stack;GO:0005737//cytoplasm;GO:0045177//apical part of cell;GO:0005794//Golgi apparatus;GO:0032154//cleavage furrow;GO:0098793//presynapse;GO:0005829//cytosol;GO:0005622//intracellular",7296589,362.8,{"v":3.3e-100,"d":"3.30E-100"},"KOG0070","GTP-binding ADP-ribosylation factor Arf1",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K07937|1|4.8e-99|364.4|lak:106159377|ADP-ribosylation factor 1","JAV99685.1","51736.4013985771;","77794.0023849116;",0.665043574,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata] >XP_064456548.1 ADP-ribosylation factor 1 [Ornithodoros turicata]"]
["XP_064489020.1",10.06944961,9.665783783,"GO:0006559//L-phenylalanine catabolic process","GO:0004505//phenylalanine 4-monooxygenase activity;GO:0005506//iron ion binding",null,7295194,604.7,{"v":1.2e-172,"d":"1.20E-172"},"KOG3820","Aromatic amino acid hydroxylase",null,"E","Amino acid transport and metabolism","METABOLISM","K00500|1|4.1e-181|638.3|tut:107359903|phenylalanine-4-hydroxylase [EC:1.14.16.1]","XP_064489020.1","15768.7243057339;","23610.5661649711;",0.667867267,"NA","NA","Non","protein henna-like isoform X2 [Ornithodoros turicata]"]
["JAW00678.1",12.07560054,11.67557823,"GO:0007010//cytoskeleton organization","GO:0051015//actin filament binding",null,7296888,116.3,{"v":3.3e-26,"d":"3.30E-26"},"KOG0443","Actin regulatory proteins (gelsolin/villin family)",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K05768|1|3.8e-38|161.4|isc:IscW_ISCW007199|gelsolin!K08017|3|3.6e-28|128.3|lgi:LOTGIDRAFT_221805|advillin","JAW00678.1","117662.804951363;","175536.195876126;",0.670305086,"NA","NA","Non","Sulfatase 1A, partial [Ornithodoros moubata]"]
["JAW03144.1",11.98268921,11.58945343,"GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0050790//regulation of catalytic activity","GO:0004197//cysteine-type endopeptidase activity","GO:0005764//lysosome;GO:0005615//extracellular space","Hs4503139",258.5,{"v":1.1e-68,"d":"1.10E-68"},"KOG1543","Cysteine proteinase Cathepsin L",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K01363|1|4.1e-90|335.1|isc:IscW_ISCW000080|cathepsin B [EC:3.4.22.1]","JAW03144.1","107953.237990062;","159961.623680465;",0.674869606,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW00022.1",11.83429082,11.44111066,null,"GO:0005391//sodium:potassium-exchanging ATPase activity;GO:0046872//metal ion binding;GO:0005524//ATP binding","GO:0016021//integral component of membrane",7300678,1671,0,"KOG0203","Na+/K+ ATPase, alpha subunit",null,"P","Inorganic ion transport and metabolism","METABOLISM","K01539|1|0.0e+00|1729.5|tut:107368464|sodium/potassium-transporting ATPase subunit alpha [EC:3.6.3.9]","JAW00022.1","93070.3244954029;","137900.932178002;",0.674907145,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAV98942.1",9.800874305,9.419052544,"GO:0015991//ATP hydrolysis coupled proton transport","GO:0046961//proton-transporting ATPase activity, rotational mechanism","GO:0000221//vacuolar proton-transporting V-type ATPase, V1 domain",7298328,534.6,{"v":1.7e-151,"d":"1.70E-151"},"KOG2759","Vacuolar H+-ATPase V1 sector, subunit H",null,"C","Energy production and conversion","METABOLISM","K02144|1|2.2e-191|672.5|acep:105627677|V-type H+-transporting ATPase subunit H","JAV98942.1","12320.9031739963;","18049.518819159;",0.682616711,"NA","NA","Non","V-type proton ATPase subunit H variant-2, partial [Ornithodoros moubata]"]
["JAR86796.1",10.94599897,10.56995452,{"$nulls":3},7294111,332.8,{"v":8.3e-91,"d":"8.30E-91"},"KOG4244","Failed axon connections (fax) protein/glutathione S-transferase-like protein",null,"T","Signal transduction mechanisms","CELLULAR PROCESSES AND SIGNALING",null,"JAR86796.1","38946.9022502767;","56726.6258569535;",0.686571811,"NA","NA","Non","failed axon, partial [Alectorobius mimon]"]
["JAW05058.1",11.54363144,11.17200427,null,"GO:0004303//estradiol 17-beta-dehydrogenase activity;GO:0016491//oxidoreductase activity","GO:0016021//integral component of membrane","Hs7705855",276.2,{"v":7.7e-74,"d":"7.70E-74"},"KOG1014","17 beta-hydroxysteroid dehydrogenase type 3, HSD17B3",null,"I","Lipid transport and metabolism","METABOLISM","K10251|1|1.3e-124|450.3|isc:IscW_ISCW003401|17beta-estradiol 17-dehydrogenase / very-long-chain 3-oxoacyl-CoA reductase [EC:1.1.1.62 1.1.1.330]","JAW05058.1","71111.4943461516;","103118.226444829;",0.689611301,"NA","NA","Non","Hydroxysteroid 17-beta dehydrogenase, partial [Ornithodoros moubata]"]
["JAW04052.1",9.795313587,9.425513374,"GO:0051603//proteolysis involved in cellular protein catabolic process","GO:0004298//threonine-type endopeptidase activity","GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005839//proteasome core complex","Hs4506199",258.8,{"v":9.2e-69,"d":"9.20E-69"},"KOG0185","20S proteasome, regulatory subunit beta type PSMB4/PRE4",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K02736|1|4.5e-79|298.5|nvl:108557920|20S proteasome subunit beta 7 [EC:3.4.25.1]","JAW04052.1","12400.7641420481;","17949.4290660028;",0.690872345,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW04533.1",9.973246231,9.608245239,"GO:0006729//tetrahydrobiopterin biosynthetic process","GO:0008124//4-alpha-hydroxytetrahydrobiopterin dehydratase activity",null,"CE18240",137.5,{"v":1.7e-32,"d":"1.70E-32"},"KOG4073","Pterin carbinolamine dehydratase PCBD/dimerization cofactor of HNF1",null,"K","Transcription","INFORMATION STORAGE AND PROCESSING","K01724|1|9.1e-34|147.1|spis:111324934|4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]","JAW04533.1","14887.0239856617;","21444.9878694108;",0.694195962,"NA","NA","Non","Pterin-4-alpha-carbinolamine dehydratase 2, partial [Ornithodoros moubata]"]
["JAR87232.1",10.84205137,10.47827888,"GO:0030316//osteoclast differentiation;GO:0043066//negative regulation of apoptotic process;GO:0006357//regulation of transcription from RNA polymerase II promoter","GO:0008270//zinc ion binding;GO:0004462//lactoylglutathione lyase activity","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0005829//cytosol","Hs5729842",250,{"v":2.8e-66,"d":"2.80E-66"},"KOG2944","Glyoxalase",null,"G","Carbohydrate transport and metabolism","METABOLISM","K01759|1|3.9e-71|271.6|gga:421428|lactoylglutathione lyase [EC:4.4.1.5]","JAR87232.1","35535.1947180624;","51126.1492144435;",0.69504931,"NA","NA","Non","lactoylglutathione lyase, partial [Alectorobius mimon]"]
["JAV98709.1",13.02891653,12.66806725,"GO:0009615//response to virus;GO:0033344//cholesterol efflux;GO:0032367//intracellular cholesterol transport;GO:0042632//cholesterol homeostasis","GO:0015485//cholesterol binding;GO:0019899//enzyme binding;GO:0017127//cholesterol transporter activity","GO:0005622//intracellular;GO:0005764//lysosome;GO:0070062//extracellular exosome","Hs5453678",116.3,{"v":4.3e-26,"d":"4.30E-26"},"KOG4063","Major epididymal secretory protein HE1",null,"S","Function unknown","POORLY CHARACTERIZED","K13443|1|1.6e-36|156.4|isc:IscW_ISCW016201|Niemann-Pick C2 protein","JAV98709.1","317447.348006024;","455393.211746366;",0.697084058,"NA","NA","Non","Major epididymal secretory protein HE1, partial [Ornithodoros moubata]"]
["XP_064455927.1",12.15072004,11.79397382,"GO:0006891//intra-Golgi vesicle-mediated transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0042147//retrograde transport, endosome to Golgi","GO:0003924//GTPase activity;GO:0004767//sphingomyelin phosphodiesterase activity;GO:0005525//GTP binding","GO:0005794//Golgi apparatus;GO:0005829//cytosol",7297923,362.5,{"v":4.9e-100,"d":"4.90E-100"},"KOG0094","GTPase Rab6/YPT6/Ryh1, small G protein superfamily",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K07893|1|9.8e-104|380.2|isc:IscW_ISCW010707|Ras-related protein Rab-6A","XP_064455927.1","132451.764365962;","189230.293921581;",0.699950106,"NA","NA","Non","ras-related protein Rab6 isoform X2 [Ornithodoros turicata]"]
["JAW06217.1",9.413089317,9.063439171,"GO:0002181//cytoplasmic translation;GO:0000463//maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)","GO:0003735//structural constituent of ribosome;GO:0003723//RNA binding","GO:0022625//cytosolic large ribosomal subunit","Hs15431301",328.9,{"v":7.2e-90,"d":"7.20E-90"},"KOG3184","60S ribosomal protein L7",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K02937|1|3.0e-123|445.3|isc:IscW_ISCW004030|large subunit ribosomal protein L7e","JAW06217.1","8633.79274460336;","12247.6494612075;",0.704934671,"NA","NA","Non","Ribosomal protein L7-like Ribosomal protein, partial [Ornithodoros moubata]"]
["JAW03267.1",8.956169283,8.60679889,null,"GO:0003995//acyl-CoA dehydrogenase activity;GO:0050660//flavin adenine dinucleotide binding;GO:0004361//glutaryl-CoA dehydrogenase activity",null,"Hs4503943",601.3,{"v":1.3e-171,"d":"1.30E-171"},"KOG0138","Glutaryl-CoA dehydrogenase",null,"E","Amino acid transport and metabolism","METABOLISM","K00252|1|3.1e-189|665.2|isc:IscW_ISCW010793|glutaryl-CoA dehydrogenase [EC:1.3.8.6]","JAW03267.1","5468.71467254921;","7755.59100933129;",0.705131906,"NA","NA","Non","DNA-directed RNA polymerase subunit, partial [Ornithodoros moubata]"]
["XP_064477465.1",11.12840518,10.78314291,"GO:0006979//response to oxidative stress","GO:0004602//glutathione peroxidase activity",null,"Hs4504107",221.1,{"v":1.8e-57,"d":"1.80E-57"},"KOG1651","Glutathione peroxidase",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K05361|1|2.4e-65|252.7|lak:106176464|phospholipid-hydroperoxide glutathione peroxidase [EC:1.11.1.12]","XP_064477465.1","48201.3791362828;","68077.7137717078;",0.708034634,"NA","NA","Non","glutathione peroxidase-like [Ornithodoros turicata]"]
["XP_064463925.1",9.414289656,9.069203658,"GO:0003374//dynamin family protein polymerization involved in mitochondrial fission;GO:0000266//mitochondrial fission;GO:0072583//clathrin-dependent endocytosis;GO:0061025//membrane fusion","GO:0008017//microtubule binding;GO:0003924//GTPase activity;GO:0005525//GTP binding","GO:0031966//mitochondrial membrane","Hs4758182",1192.9,0,"KOG0446","Vacuolar sorting protein VPS1, dynamin, and related proteins",null,"UR","Intracellular trafficking, secretion, and vesicular transport;General function prediction only","CELLULAR PROCESSES AND SIGNALING;POORLY CHARACTERIZED","K01528|1|0.0e+00|1527.7|isc:IscW_ISCW005274|dynamin GTPase [EC:3.6.5.5]","XP_064463925.1","8683.70584963575;","12262.3596218986;",0.70815945,"NA","NA","Non","dynamin-like isoform X6 [Ornithodoros turicata]"]
["JAW04101.1",12.74911787,12.42065356,"GO:0006542//glutamine biosynthetic process","GO:0004356//glutamate-ammonia ligase activity;GO:0005524//ATP binding",null,7292645,513.8,{"v":2.5e-145,"d":"2.50E-145"},"KOG0683","Glutamine synthetase",null,"E","Amino acid transport and metabolism","METABOLISM","K01915|1|4.7e-155|551.6|dpa:109546372|glutamine synthetase [EC:6.3.1.2]","JAW04101.1","247868.479590867;","344248.090400696;",0.720028626,"NA","NA","Non","Glutamine synthetase, partial [Ornithodoros moubata]"]
["JAW02987.1",10.78884069,10.46060734,"GO:0006457//protein folding;GO:0006458//'de novo' protein folding;GO:0061077//chaperone-mediated protein folding","GO:0044183//protein binding involved in protein folding;GO:0016740//transferase activity;GO:0051082//unfolded protein binding;GO:0005524//ATP binding","GO:0005737//cytoplasm;GO:0005832//chaperonin-containing T-complex","Hs5453605",762.7,{"v":4.1e-220,"d":"4.10E-220"},"KOG0358","Chaperonin complex component, TCP-1 delta subunit (CCT4)",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K09496|1|1.8e-242|842.4|isc:IscW_ISCW007627|T-complex protein 1 subunit delta","JAW02987.1","34912.7489376585;","48476.8037786285;",0.720194943,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW01220.1",11.54548275,11.22620621,"GO:0032259//methylation","GO:0008168//methyltransferase activity;GO:0008757//S-adenosylmethionine-dependent methyltransferase activity","GO:0005737//cytoplasm;GO:0045335//phagocytic vesicle","At3g54150",58.2,{"v":2.3e-08,"d":"2.30E-08"},"KOG3010","Methyltransferase",null,"R","General function prediction only","POORLY CHARACTERIZED",null,"JAW01220.1","75072.2460337221;","103309.306882672;",0.726674569,"NA","NA","Non","Membrane protein, partial [Ornithodoros moubata]"]
["JAV99640.1",12.23682274,11.91853175,"GO:0006457//protein folding","GO:0003755//peptidyl-prolyl cis-trans isomerase activity","GO:0005737//cytoplasm;GO:0005634//nucleus",7293206,293.9,{"v":2.1e-79,"d":"2.10E-79"},"KOG0865","Cyclophilin type peptidyl-prolyl cis-trans isomerase",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K09565|1|1.8e-91|339.3|isc:IscW_ISCW008497|peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]","JAV99640.1","150021.177337364;","206245.551958127;",0.727391092,"NA","NA","Non","Peptidyl-prolyl cis-trans isomerase, partial [Ornithodoros moubata]"]
["JAW02205.1",9.942949585,9.625684586,"GO:0006457//protein folding;GO:0030150//protein import into mitochondrial matrix","GO:0016853//isomerase activity;GO:0051087//chaperone binding;GO:0051082//unfolded protein binding;GO:0004750//ribulose-phosphate 3-epimerase activity;GO:0000774//adenyl-nucleotide exchange factor activity;GO:0042803//protein homodimerization activity","GO:0005634//nucleus;GO:0001405//presequence translocase-associated import motor;GO:0005759//mitochondrial matrix","Hs18559169",188.7,{"v":1.1e-47,"d":"1.10E-47"},"KOG3003","Molecular chaperone of the GrpE family",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K03687|1|5.5e-68|261.5|isc:IscW_ISCW005818|molecular chaperone GrpE","JAW02205.1","15148.9209838317;","20805.020053776;",0.728137774,"NA","NA","Non","Glypican, partial [Ornithodoros moubata]"]
["XP_064486715.1",9.580394821,9.266314776,"GO:0007507//heart development;GO:0003428//chondrocyte intercalation involved in growth plate cartilage morphogenesis;GO:0007165//signal transduction","GO:0003924//GTPase activity;GO:0004708//MAP kinase kinase activity;GO:0005525//GTP binding","GO:0016020//membrane;GO:0005622//intracellular","Hs4506413",324.7,{"v":1e-88,"d":"1.00E-88"},"KOG0395","Ras-related GTPase",null,"R","General function prediction only","POORLY CHARACTERIZED","K04353|1|1.8e-93|345.9|tut:107362689|Ras-related protein Rap-1A!K07836|4|1.7e-91|339.3|bfo:BRAFLDRAFT_209131|Ras-related protein Rap-1B","XP_064486715.1","10575.7061368637;","14478.1344451782;",0.730460556,"NA","NA","Non","ras-related protein Rap-1b [Ornithodoros turicata] >XP_064486716.1 ras-related protein Rap-1b [Ornithodoros turicata]"]
["XP_064476942.1",11.8270395,11.51418156,null,"GO:0005509//calcium ion binding",null,"Hs21389521",221.5,{"v":1.2e-57,"d":"1.20E-57"},"KOG0032","Ca2+/calmodulin-dependent protein kinase, EF-Hand protein superfamily",null,"T","Signal transduction mechanisms","CELLULAR PROCESSES AND SIGNALING","K02183|1|4.7e-12|75.5|pmur:107297355|calmodulin!K05865|4|9.8e-10|67.8|pret:103468062|troponin C, slow skeletal and cardiac muscles","XP_064476942.1","100125.688694982;","136904.584180675;",0.731353806,"NA","NA","Non","calcyphosin-like protein [Ornithodoros turicata] >XP_064476943.1 calcyphosin-like protein [Ornithodoros turicata]"]
["XP_064455264.1",11.14295652,10.84192772,"GO:0016998//cell wall macromolecule catabolic process;GO:0050830//defense response to Gram-positive bacterium;GO:0008152//metabolic process;GO:0050829//defense response to Gram-negative bacterium","GO:0003796//lysozyme activity","GO:0005615//extracellular space",{"$nulls":9},"K13915|1|6.3e-41|171.0|bfo:BRAFLDRAFT_287383|lysozyme C [EC:3.2.1.17]","XP_064455264.1","51119.8277481769;","69075.5782804464;",0.740056457,"NA","NA","Non","lysozyme-like [Ornithodoros turicata] >XP_064455265.1 lysozyme-like [Ornithodoros turicata]"]
["XP_064458335.1",11.52105396,11.22373925,"GO:0006520//cellular amino acid metabolic process","GO:0004353//glutamate dehydrogenase [NAD(P)+] activity;GO:0016639//oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor",null,7301074,792.7,{"v":3.9e-229,"d":"3.90E-229"},"KOG2250","Glutamate/leucine/phenylalanine/valine dehydrogenases",null,"E","Amino acid transport and metabolism","METABOLISM","K00261|1|7.0e-266|920.2|tut:107370853|glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]","XP_064458335.1","74887.2739386021;","100816.162122237;",0.742810204,"NA","NA","Non","glutamate dehydrogenase, mitochondrial-like [Ornithodoros turicata] >XP_064458336.1 glutamate dehydrogenase, mitochondrial-like [Ornithodoros turicata]"]
["JAW05899.1",12.92440298,12.63372548,"GO:1903061//positive regulation of protein lipidation;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0043407//negative regulation of MAP kinase activity;GO:1905037//autophagosome organization;GO:0043243//positive regulation of protein complex disassembly;GO:0071356//cellular response to tumor necrosis factor;GO:0006680//glucosylceramide catabolic process;GO:0006665//sphingolipid metabolic process;GO:0032463//negative regulation of protein homooligomerization;GO:1904925//positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization;GO:0023021//termination of signal transduction;GO:0009267//cellular response to starvation;GO:1901215//negative regulation of neuron death;GO:0035307//positive regulation of protein dephosphorylation;GO:1904457//positive regulation of neuronal action potential;GO:0032715//negative regulation of interleukin-6 production;GO:0046512//sphingosine biosynthetic process;GO:0046513//ceramide biosynthetic process","GO:0004348//glucosylceramidase activity;GO:0005102//receptor binding","GO:0043202//lysosomal lumen;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome;GO:0005764//lysosome;GO:0005765//lysosomal membrane","Hs4503935",476.5,{"v":5.6e-134,"d":"5.60E-134"},"KOG2566","Beta-glucocerebrosidase",null,"G","Carbohydrate transport and metabolism","METABOLISM","K01201|1|3.6e-168|595.5|isc:IscW_ISCW004661|glucosylceramidase [EC:3.2.1.45]","JAW05899.1","306730.710749069;","410201.171684953;",0.747756788,"NA","NA","Non","Glucosylceramidase, partial [Ornithodoros moubata]"]
["XP_064467265.1",15.06956019,14.78434951,"GO:0000086//G2/M transition of mitotic cell cycle;GO:0006928//movement of cell or subcellular component;GO:0097711//ciliary basal body-plasma membrane docking;GO:0010389//regulation of G2/M transition of mitotic cell cycle;GO:0007017//microtubule-based process;GO:0042267//natural killer cell mediated cytotoxicity;GO:0043312//neutrophil degranulation","GO:0005200//structural constituent of cytoskeleton;GO:0051082//unfolded protein binding;GO:0003725//double-stranded RNA binding;GO:0005525//GTP binding;GO:0042288//MHC class I protein binding;GO:0003924//GTPase activity","GO:0035578//azurophil granule lumen;GO:0005874//microtubule;GO:0005737//cytoplasm;GO:1903561//extracellular vesicle;GO:0070062//extracellular exosome;GO:0043209//myelin sheath;GO:0005634//nucleus;GO:0005856//cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0031012//extracellular matrix;GO:0045298//tubulin complex;GO:0005829//cytosol;GO:0005623//cell;GO:0005576//extracellular region","Hs5174735",891,{"v":8.5e-259,"d":"8.50E-259"},"KOG1375","Beta tubulin",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K07375|1|6.3e-257|890.2|ovi:T265_07282|tubulin beta","XP_064467265.1","2634883.45401005;","3504506.22073555;",0.751855836,"NA","NA","Non","tubulin beta chain [Ornithodoros turicata]"]
["JAW02383.1",10.55903513,10.27532792,"GO:0042989//sequestering of actin monomers;GO:0030837//negative regulation of actin filament polymerization;GO:0051016//barbed-end actin filament capping;GO:0043538//regulation of actin phosphorylation;GO:0010613//positive regulation of cardiac muscle hypertrophy","GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0003779//actin binding;GO:0004713//protein tyrosine kinase activity;GO:0032403//protein complex binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0003785//actin monomer binding;GO:0045296//cadherin binding","GO:0015629//actin cytoskeleton;GO:0030016//myofibril;GO:0005925//focal adhesion;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm;GO:0005911//cell-cell junction;GO:0032587//ruffle membrane;GO:0030175//filopodium;GO:0005622//intracellular;GO:0005829//cytosol","Hs4506275",410.6,{"v":2.6e-114,"d":"2.60E-114"},"KOG1747","Protein tyrosine kinase 9/actin monomer-binding protein",null,"W","Extracellular structures","CELLULAR PROCESSES AND SIGNALING","K08870|1|8.9e-142|507.3|isc:IscW_ISCW017374|twinfilin","JAW02383.1","29008.0286123263;","38523.9393852374;",0.75298708,"NA","NA","Non","Leukotriene A 4 hydrolase, partial [Ornithodoros moubata]"]
["XP_064459415.1",9.707226329,9.43444674,"GO:0006807//nitrogen compound metabolic process","GO:0016151//nickel cation binding;GO:0003924//GTPase activity",{"$nulls":10},"K03189|1|1.6e-103|379.8|myi:110458925|urease accessory protein","XP_064459415.1","12512.0410056204;","16435.9506773689;",0.761260559,"NA","NA","Non","urease accessory protein UreG-like [Ornithodoros turicata]"]
["JAV98702.1",11.94521139,11.67480438,"GO:0006730//one-carbon metabolic process;GO:0019510//S-adenosylhomocysteine catabolic process;GO:0033353//S-adenosylmethionine cycle","GO:0051287//NAD binding;GO:0004013//adenosylhomocysteinase activity","GO:0005829//cytosol",7293068,703.4,{"v":2.4e-202,"d":"2.40E-202"},"KOG1370","S-adenosylhomocysteine hydrolase",null,"H","Coenzyme transport and metabolism","METABOLISM","K01251|1|1.2e-215|753.1|isc:IscW_ISCW015944|adenosylhomocysteinase [EC:3.3.1.1]","JAV98702.1","117571.786936304;","154077.559404012;",0.763068856,"NA","NA","Non","Adenosylhomocysteinase, partial [Ornithodoros moubata]"]
["JAV98701.1",13.33986149,13.07180439,"GO:0008154//actin polymerization or depolymerization;GO:0000902//cell morphogenesis;GO:0045761//regulation of adenylate cyclase activity;GO:0007163//establishment or maintenance of cell polarity;GO:0007165//signal transduction","GO:0003779//actin binding;GO:0008179//adenylate cyclase binding","GO:0030864//cortical actin cytoskeleton","Hs5453595",446.4,{"v":5.9e-125,"d":"5.90E-125"},"KOG2675","Adenylate cyclase-associated protein (CAP/Srv2p)",null,"ZT","Cytoskeleton;Signal transduction mechanisms","CELLULAR PROCESSES AND SIGNALING;CELLULAR PROCESSES AND SIGNALING","K17261|1|1.2e-194|683.3|isc:IscW_ISCW023355|adenylyl cyclase-associated protein","JAV98701.1","475348.923808503;","621481.541529116;",0.764864106,"NA","NA","Non","Adenylyl cyclase-associated protein, partial [Ornithodoros moubata]"]
["JAV99593.1",10.75950898,10.50009972,null,"GO:0008239//dipeptidyl-peptidase activity;GO:0046872//metal ion binding;GO:0008237//metallopeptidase activity","GO:0005737//cytoplasm","Hs18491024",757.7,{"v":1.8e-218,"d":"1.80E-218"},"KOG3675","Dipeptidyl peptidase III",null,"R","General function prediction only","POORLY CHARACTERIZED","K01277|1|4.0e-306|1054.3|isc:IscW_ISCW013099|dipeptidyl-peptidase III [EC:3.4.14.4]","JAV99593.1","36319.1240735712;","47075.5472344424;",0.771507209,"NA","NA","Non","GE25873, partial [Ornithodoros moubata]"]
["JAW06005.1",12.81360132,12.55423381,"GO:0007166//cell surface receptor signaling pathway",null,"GO:0016021//integral component of membrane;GO:0005887//integral component of plasma membrane","CE26006",127.5,{"v":2.7e-29,"d":"2.70E-29"},"KOG3882","Tetraspanin family integral membrane protein",null,"R","General function prediction only","POORLY CHARACTERIZED","K06497|1|1.6e-66|256.5|isc:IscW_ISCW004397|CD63 antigen","JAW06005.1","283292.103838857;","367177.742941923;",0.771539423,"NA","NA","Non","Tetraspanin, partial [Ornithodoros moubata]"]
["JAV98962.1",8.674446359,8.415568444,"GO:0031204//posttranslational protein targeting to membrane, translocation","GO:0008565//protein transporter activity","GO:0016021//integral component of membrane;GO:0005622//intracellular","7295249_1",294.7,{"v":4e-79,"d":"4.00E-79"},"KOG0721","Molecular chaperone (DnaJ superfamily)",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K09540|1|8.0e-192|674.5|isc:IscW_ISCW007192|translocation protein SEC63","JAV98962.1","4516.84239893144;","5851.45928110611;",0.771917257,"NA","NA","Non","Translocation protein SEC63-like protein, partial [Ornithodoros moubata]"]
["JAV98914.1",13.4539803,13.1969312,null,"GO:0051015//actin filament binding;GO:0003774//motor activity;GO:0005524//ATP binding","GO:0016459//myosin complex",7291892,1193.7,0,"KOG0161","Myosin class II heavy chain",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K10352|1|0.0e+00|1258.0|zne:110839098|myosin heavy chain","JAV98914.1","538709.206549624;","696609.516852687;",0.773330242,"NA","NA","Non","Myosin heavy chain non-muscle, partial [Ornithodoros moubata]"]
["JAV99156.1",9.829122197,9.572201865,"GO:0042391//regulation of membrane potential;GO:0007369//gastrulation;GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0048240//sperm capacitation;GO:0006508//proteolysis;GO:0045454//cell redox homeostasis","GO:0034604//pyruvate dehydrogenase (NAD+) activity;GO:0004148//dihydrolipoyl dehydrogenase activity;GO:0050660//flavin adenine dinucleotide binding;GO:0009055//electron transfer activity","GO:0045254//pyruvate dehydrogenase complex;GO:0043209//myelin sheath;GO:0005739//mitochondrion;GO:0005654//nucleoplasm;GO:0005623//cell;GO:0005929//cilium;GO:0043159//acrosomal matrix","Hs4557525",742.7,{"v":4.3e-214,"d":"4.30E-214"},"KOG1335","Dihydrolipoamide dehydrogenase",null,"C","Energy production and conversion","METABOLISM","K00382|1|6.6e-218|760.8|phu:Phum_PHUM336850|dihydrolipoamide dehydrogenase [EC:1.8.1.4]","JAV99156.1","14360.0003178197;","18566.6492104658;",0.773429829,"NA","NA","Non","Dihydrolipoyl dehydrogenase, partial [Ornithodoros moubata]"]
["XP_064488255.1",13.33202235,13.08517964,"GO:0008104//protein localization;GO:0016336//establishment or maintenance of polarity of larval imaginal disc epithelium;GO:0034453//microtubule anchoring;GO:0032956//regulation of actin cytoskeleton organization;GO:0045197//establishment or maintenance of epithelial cell apical/basal polarity;GO:0030036//actin cytoskeleton organization;GO:0030866//cortical actin cytoskeleton organization;GO:0042052//rhabdomere development;GO:0002009//morphogenesis of an epithelium;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0007368//determination of left/right symmetry;GO:0042048//olfactory behavior;GO:0006405//RNA export from nucleus;GO:0008284//positive regulation of cell proliferation;GO:0030029//actin filament-based process;GO:0072499//photoreceptor cell axon guidance;GO:0007315//pole plasm assembly;GO:0008360//regulation of cell shape;GO:0043622//cortical microtubule organization;GO:0045313//rhabdomere membrane biogenesis;GO:0007318//pole plasm protein localization;GO:0035149//lumen formation, open tracheal system;GO:0007010//cytoskeleton organization;GO:0009952//anterior/posterior pattern specification;GO:0016057//regulation of membrane potential in photoreceptor cell;GO:0045433//male courtship behavior, veined wing generated song production;GO:0007314//oocyte anterior/posterior axis specification;GO:0042462//eye photoreceptor cell development;GO:0045807//positive regulation of endocytosis;GO:1902846//positive regulation of mitotic spindle elongation","GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0003779//actin binding;GO:0008017//microtubule binding;GO:0008092//cytoskeletal protein binding","GO:0035003//subapical complex;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0016324//apical plasma membrane;GO:0032154//cleavage furrow;GO:1990023//mitotic spindle midzone;GO:0035327//transcriptionally active chromatin;GO:0005912//adherens junction;GO:0005886//plasma membrane;GO:0005829//cytosol;GO:0005703//polytene chromosome puff;GO:0005634//nucleus;GO:0005938//cell cortex",7290977,756.5,{"v":3.2e-218,"d":"3.20E-218"},"KOG3529","Radixin, moesin and related proteins of the ERM family",null,"R","General function prediction only","POORLY CHARACTERIZED","K05762|1|8.9e-256|886.7|dpx:DAPPUDRAFT_327006|radixin","XP_064488255.1","481749.545512657;","616628.705012455;",0.781263573,"NA","NA","Non","moesin/ezrin/radixin homolog 1-like [Ornithodoros turicata]"]
["XP_064484277.1",12.22640097,11.98074841,"GO:0051693//actin filament capping","GO:0016787//hydrolase activity;GO:0005200//structural constituent of cytoskeleton;GO:0005543//phospholipid binding;GO:0003779//actin binding","GO:0008091//spectrin",7293373,3040.8,0,"KOG0517","Beta-spectrin",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K06115|1|0.0e+00|3614.3|isc:IscW_ISCW021585|spectrin beta","XP_064484277.1","159651.470543614;","204107.270867972;",0.782193941,"NA","NA","Non","spectrin beta chain-like isoform X8 [Ornithodoros turicata]"]
["XP_064467935.1",11.11074101,10.86537139,"GO:0006334//nucleosome assembly","GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity","GO:0005634//nucleus;GO:0000786//nucleosome","CE07075E",195.7,{"v":4.7e-50,"d":"4.70E-50"},"KOG1744","Histone H2B",null,"B","Chromatin structure and dynamics","INFORMATION STORAGE AND PROCESSING","K11252|1|2.3e-60|235.3|tut:107361624|histone H2B","XP_064467935.1","52332.4225939639;","66885.7358023027;",0.782415293,"NA","NA","Non","histone H2B [Ornithodoros turicata] >XP_064467940.1 histone H2B [Ornithodoros turicata] >XP_064468446.1 histone H2B [Ornithodoros turicata] >XP_064468447.1 histone H2B [Ornithodoros turicata] >XP_064468448.1 histone H2B [Ornithodoros turicata]"]
["JAW05818.1",10.98839594,10.74629011,null,"GO:0016491//oxidoreductase activity",null,"Hs15277342",267.3,{"v":2.6e-71,"d":"2.60E-71"},"KOG1200","Mitochondrial/plastidial beta-ketoacyl-ACP reductase",null,"I","Lipid transport and metabolism","METABOLISM","K13370|1|9.6e-77|290.8|lgi:LOTGIDRAFT_190314|17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:1.1.1.62 1.1.1.239]","JAW05818.1","46457.356525151;","59183.3743435136;",0.784973095,"NA","NA","Non","Estradiol 17-beta-dehydrogenase 8, partial [Ornithodoros moubata]"]
["JAV99545.1",8.893429395,8.651628734,"GO:0006189//'de novo' IMP biosynthetic process;GO:0044208//'de novo' AMP biosynthetic process","GO:0004018//N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity;GO:0070626//(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity",null,"Hs4557269",681.4,{"v":1.1e-195,"d":"1.10E-195"},"KOG2700","Adenylosuccinate lyase",null,"F","Nucleotide transport and metabolism","METABOLISM","K01756|1|5.0e-236|820.8|isc:IscW_ISCW016257|adenylosuccinate lyase [EC:4.3.2.2]","JAV99545.1","5719.45462371194;","7283.95596036822;",0.785212686,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW00010.1",9.006447221,8.767950516,null,"GO:0005525//GTP binding",null,7300634,614,{"v":1.9e-175,"d":"1.90E-175"},"KOG3859","Septins (P-loop GTPases)",null,"D","Cell cycle control, cell division, chromosome partitioning","CELLULAR PROCESSES AND SIGNALING","K16939|1|3.4e-199|698.4|isc:IscW_ISCW018518|septin 6/8/11","JAW00010.1","6424.99104366984;","8155.49506853245;",0.787811284,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW01770.1",9.740617201,9.50267433,"GO:0006750//glutathione biosynthetic process","GO:0004357//glutamate-cysteine ligase activity","GO:0017109//glutamate-cysteine ligase complex","Hs4557625",500,{"v":3.9e-141,"d":"3.90E-141"},"KOG3754","Gamma-glutamylcysteine synthetase",null,"H","Coenzyme transport and metabolism","METABOLISM","K11204|1|1.5e-180|636.3|isc:IscW_ISCW005918|glutamate--cysteine ligase catalytic subunit [EC:6.3.2.2]","JAW01770.1","13395.5029646937;","16994.026876785;",0.788247721,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW06547.1",11.05010221,10.8192734,"GO:0006974//cellular response to DNA damage stimulus;GO:0016567//protein ubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006464//cellular protein modification process","GO:0016881//acid-amino acid ligase activity;GO:0008641//ubiquitin-like modifier activating enzyme activity;GO:0004839//ubiquitin activating enzyme activity;GO:0005524//ATP binding","GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005739//mitochondrion","Hs4507763",153.3,{"v":2.7e-37,"d":"2.70E-37"},"KOG2012","Ubiquitin activating enzyme UBA1",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K03178|1|2.5e-46|188.7|isc:IscW_ISCW019123|ubiquitin-activating enzyme E1 [EC:6.2.1.45]","JAW06547.1","49974.7623974338;","62950.3886895723;",0.793875359,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["XP_064478099.1",14.23100271,14.0002019,null,"GO:0051015//actin filament binding;GO:0003774//motor activity;GO:0005524//ATP binding","GO:0016459//myosin complex",7291892,2669,0,"KOG0161","Myosin class II heavy chain",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K10352|1|0.0e+00|2768.0|bter:100649130|myosin heavy chain","XP_064478099.1","1202847.10998065;","1515116.22095827;",0.793897586,"NA","NA","Non","myosin heavy chain, non-muscle-like isoform X2 [Ornithodoros turicata]"]
["ABR23464.1",11.08785325,10.86222462,{"$nulls":3},"Hs5174447",557,{"v":2.1e-158,"d":"2.10E-158"},"KOG0279","G protein beta subunit-like protein",null,"T","Signal transduction mechanisms","CELLULAR PROCESSES AND SIGNALING","K14753|1|1.9e-159|565.8|hst:105186624|guanine nucleotide-binding protein subunit beta-2-like 1 protein","ABR23464.1","52168.0029538572;","65372.2574136688;",0.798014403,"NA","NA","Non","G protein beta subunit-like protein [Ornithodoros parkeri]"]
["JAW03208.1",14.542418,14.31778539,null,"GO:0004190//aspartic-type endopeptidase activity","GO:0005764//lysosome","Hs4503143",400.6,{"v":3.1e-111,"d":"3.10E-111"},"KOG1339","Aspartyl protease",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K01379|1|2.2e-112|409.8|pdam:113677634|cathepsin D [EC:3.4.23.5]","JAW03208.1","1652476.10437246;","2068673.21636824;",0.798809639,"NA","NA","Non","Uracil phosphoribosyltransferase-like protein, partial [Ornithodoros moubata]"]
["AAS55945.1",15.91127882,15.6903132,"GO:0000281//mitotic cytokinesis;GO:0030866//cortical actin cytoskeleton organization;GO:0040011//locomotion;GO:0009792//embryo development ending in birth or egg hatching;GO:0007111//meiosis II cytokinesis","GO:0005524//ATP binding","GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005938//cell cortex;GO:0005884//actin filament",7290649,759.6,{"v":2.5e-219,"d":"2.50E-219"},"KOG0676","Actin and related proteins",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K05692|1|3.7e-218|761.1|nvi:100116604|actin beta/gamma 1","AAS55945.1","6519532.3367312;","8131685.83937258;",0.801744247,"NA","NA","Non","actin [Ornithodoros moubata] >XP_064455196.1 actin-5C-like [Ornithodoros turicata]"]
["XP_064484793.1",7.627895503,7.4087856,"GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043248//proteasome assembly;GO:0006508//proteolysis",null,"GO:0005838//proteasome regulatory particle;GO:0005634//nucleus;GO:0005829//cytosol;GO:0008541//proteasome regulatory particle, lid subcomplex","Hs4506233",334.7,{"v":1.4e-91,"d":"1.40E-91"},"KOG3151","26S proteasome regulatory complex, subunit RPN12/PSMD8",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K03031|1|3.2e-99|365.5|myi:110449289|26S proteasome regulatory subunit N12","XP_064484793.1","1650.42085887113;","2054.72131138284;",0.803233436,"NA","NA","Non","26S proteasome non-ATPase regulatory subunit 8-like [Ornithodoros turicata]"]
["JAW02444.1",10.32324453,10.10551697,"GO:0006886//intracellular protein transport",null,"GO:0005622//intracellular",7294938,399.4,{"v":8.6e-111,"d":"8.60E-111"},"KOG1087","Cytosolic sorting protein GGA2/TOM1",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K16677|1|8.7e-34|149.1|epa:110251865|dachs!K12404|2|1.3e-24|118.6|amex:103043997|ADP-ribosylation factor-binding protein GGA!K04705|5|2.2e-24|117.9|tut:107360834|signal transducing adaptor molecule","JAW02444.1","24477.6803143861;","30431.8344937039;",0.804344553,"NA","NA","Non","TOM1-like protein 2, partial [Ornithodoros moubata]"]
["JAV99218.1",9.385712699,9.168024034,"GO:0006099//tricarboxylic acid cycle","GO:0004449//isocitrate dehydrogenase (NAD+) activity;GO:0000287//magnesium ion binding;GO:0051287//NAD binding","GO:0005739//mitochondrion","Hs4758582",379.4,{"v":7e-105,"d":"7.00E-105"},"KOG0784","Isocitrate dehydrogenase, gamma subunit",null,"E","Amino acid transport and metabolism","METABOLISM","K00030|1|3.0e-143|512.3|isc:IscW_ISCW017423|isocitrate dehydrogenase (NAD+) [EC:1.1.1.41]","JAV99218.1","9585.66501822113;","11916.8983223688;",0.804375833,"NA","NA","Non","Isocitrate dehydrogenase, partial [Ornithodoros moubata]"]
["JAW01437.1",10.27589599,10.05944295,"GO:0019556//histidine catabolic process to glutamate and formamide;GO:0019557//histidine catabolic process to glutamate and formate","GO:0016812//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides;GO:0050480//imidazolonepropionase activity;GO:0046872//metal ion binding","GO:0005737//cytoplasm","Hs22056401",482.6,{"v":7.5e-136,"d":"7.50E-136"},"KOG3968","Atrazine chlorohydrolase/guanine deaminase",null,"FQ","Nucleotide transport and metabolism;Secondary metabolites biosynthesis, transport and catabolism","METABOLISM;METABOLISM","K01468|1|8.5e-143|511.1|nve:NEMVE_v1g163675|imidazolonepropionase [EC:3.5.2.7]","JAW01437.1","23375.4815126708;","29024.5119038719;",0.805370357,"NA","NA","Non","hypothetical protein, partial [Ornithodoros moubata]"]
["JAV98902.1",10.64718745,10.43203031,{"$nulls":3},7301679,184.5,{"v":6.1e-46,"d":"6.10E-46"},"KOG4597","Serine proteinase inhibitor (KU family) with thrombospondin repeats",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING",null,"JAV98902.1","33929.1671620201;","42074.0925994578;",0.80641471,"NA","NA","Non","Colostrum trypsin inhibitor, partial [Ornithodoros moubata]"]
["JAW06276.1",11.68836142,11.47501011,null,"GO:0016874//ligase activity","GO:0016021//integral component of membrane;GO:0012505//endomembrane system",7303473,363.2,{"v":7.2e-100,"d":"7.20E-100"},"KOG1212","Amidases",null,"JIT","Translation, ribosomal structure and biogenesis;Lipid transport and metabolism;Signal transduction mechanisms","INFORMATION STORAGE AND PROCESSING;METABOLISM;CELLULAR PROCESSES AND SIGNALING","K19176|1|7.9e-102|375.2|zne:110830191|fatty acid amide hydrolase 2 [EC:3.5.1.99]","JAW06276.1","96279.4435424856;","119176.565780745;",0.807872277,"NA","NA","Non","Amidase, partial [Ornithodoros moubata]"]
["JAW03001.1",12.34402714,12.13647942,"GO:0031036//myosin II filament assembly;GO:0035277//spiracle morphogenesis, open tracheal system;GO:0032956//regulation of actin cytoskeleton organization;GO:0030707//ovarian follicle cell development;GO:0007300//ovarian nurse cell to oocyte transport;GO:0007298//border follicle cell migration;GO:0035317//imaginal disc-derived wing hair organization;GO:0000281//mitotic cytokinesis;GO:0035159//regulation of tube length, open tracheal system;GO:0019749//cytoskeleton-dependent cytoplasmic transport, nurse cell to oocyte;GO:0042060//wound healing;GO:0060288//formation of a compartment boundary;GO:0030048//actin filament-based movement;GO:0035148//tube formation;GO:0001736//establishment of planar polarity;GO:0003384//apical constriction involved in gastrulation;GO:0090254//cell elongation involved in imaginal disc-derived wing morphogenesis;GO:0035191//nuclear axial expansion","GO:0005509//calcium ion binding;GO:0032036//myosin heavy chain binding","GO:0005737//cytoplasm;GO:0045177//apical part of cell;GO:0048471//perinuclear region of cytoplasm;GO:0035183//female germline ring canal inner rim;GO:0031941//filamentous actin;GO:0016324//apical plasma membrane;GO:0032154//cleavage furrow;GO:0005938//cell cortex;GO:0005911//cell-cell junction;GO:0005886//plasma membrane;GO:0051233//spindle midzone;GO:0005829//cytosol;GO:0030496//midbody;GO:0016460//myosin II complex;GO:0005912//adherens junction",7290684,313.2,{"v":2.8e-85,"d":"2.80E-85"},"KOG0031","Myosin regulatory light chain, EF-Hand protein superfamily",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K12757|1|1.1e-84|316.6|clec:106664184|myosin regulatory light chain 12","JAW03001.1","186554.634156074;","229584.662580447;",0.812574464,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAV98947.1",10.26528553,10.05877703,"GO:0030968//endoplasmic reticulum unfolded protein response;GO:0006486//protein glycosylation;GO:0051084//'de novo' posttranslational protein folding;GO:0071712//ER-associated misfolded protein catabolic process;GO:0018279//protein N-linked glycosylation via asparagine","GO:0051082//unfolded protein binding;GO:0003980//UDP-glucose:glycoprotein glucosyltransferase activity","GO:0005783//endoplasmic reticulum","Hs9910280",1252.7,0,"KOG1879","UDP-glucose:glycoprotein glucosyltransferase",null,"G","Carbohydrate transport and metabolism","METABOLISM","K11718|1|0.0e+00|1891.3|isc:IscW_ISCW004613|UDP-glucose:glycoprotein glucosyltransferase [EC:2.4.1.-]","JAV98947.1","23359.9203681607;","28718.1765987577;",0.813419344,"NA","NA","Non","Killer toxin-resistance protein, partial [Ornithodoros moubata]"]
["JAW03453.1",12.21052406,12.00527235,"GO:0030203//glycosaminoglycan metabolic process;GO:0007040//lysosome organization;GO:0009313//oligosaccharide catabolic process;GO:0001501//skeletal system development;GO:0019915//lipid storage;GO:0008049//male courtship behavior;GO:0044267//cellular protein metabolic process;GO:0043615//astrocyte cell migration;GO:0042552//myelination;GO:0007341//penetration of zona pellucida;GO:0050885//neuromuscular process controlling balance;GO:0006689//ganglioside catabolic process;GO:0048477//oogenesis;GO:0007626//locomotory behavior;GO:0007605//sensory perception of sound;GO:0006874//cellular calcium ion homeostasis;GO:0008360//regulation of cell shape;GO:0005975//carbohydrate metabolic process;GO:0008654//phospholipid biosynthetic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter","GO:0008375//acetylglucosaminyltransferase activity;GO:0004563//beta-N-acetylhexosaminidase activity;GO:0042803//protein homodimerization activity;GO:0102148//N-acetyl-beta-D-galactosaminidase activity;GO:0046982//protein heterodimerization activity","GO:0001669//acrosomal vesicle;GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0042582//azurophil granule","Hs4504371",460.3,{"v":3e-129,"d":"3.00E-129"},"KOG2499","Beta-N-acetylhexosaminidase",null,"G","Carbohydrate transport and metabolism","METABOLISM","K12373|1|7.2e-134|481.1|gga:427204|hexosaminidase [EC:3.2.1.52]","JAW03453.1","163615.158296187;","200892.266675684;",0.814442293,"NA","NA","Non","Beta-hexosaminidase subunit alpha, partial [Ornithodoros moubata]"]
["JAV99713.1",12.52376925,12.32109614,"GO:0030048//actin filament-based movement","GO:0032036//myosin heavy chain binding;GO:0032440//2-alkenal reductase [NAD(P)] activity;GO:0017022//myosin binding;GO:0005509//calcium ion binding","GO:0016459//myosin complex;GO:0016460//myosin II complex;GO:0031477//myosin VII complex;GO:0031476//myosin VI complex;GO:0031475//myosin V complex",7290598,245,{"v":8.1e-65,"d":"8.10E-65"},"KOG0030","Myosin essential light chain, EF-Hand protein superfamily",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K12751|1|4.0e-75|284.6|isc:IscW_ISCW001124|myosin light chain 6","JAV99713.1","224379.959575623;","274791.867755974;",0.816545123,"NA","NA","Non","Myosin-2 essential light chain, partial [Ornithodoros moubata]"]
["XP_064480284.1",14.16428648,13.96520385,null,"GO:0003746//translation elongation factor activity;GO:0003924//GTPase activity;GO:0005525//GTP binding","GO:0005737//cytoplasm",7302084,817.4,{"v":1.2e-236,"d":"1.20E-236"},"KOG0052","Translation elongation factor EF-1 alpha/Tu",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K03231|1|3.2e-264|914.4|isc:IscW_ISCW020299|elongation factor 1-alpha","XP_064480284.1","1161477.9541038;","1417331.56514754;",0.819482175,"NA","NA","Non","elongation factor 1-alpha [Ornithodoros turicata]"]
["JAW01946.1",11.20383294,11.0079784,"GO:0007030//Golgi organization;GO:0000278//mitotic cell cycle;GO:0008283//cell proliferation;GO:0006414//translational elongation","GO:0003924//GTPase activity;GO:0016779//nucleotidyltransferase activity;GO:0003746//translation elongation factor activity;GO:0005525//GTP binding","GO:0005739//mitochondrion;GO:0005622//intracellular",7303306,280,{"v":2.7e-75,"d":"2.70E-75"},"KOG0460","Mitochondrial translation elongation factor Tu",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K02358|1|1.6e-83|312.8|isc:IscW_ISCW010766|elongation factor Tu","JAW01946.1","60353.7521791698;","73411.2844058014;",0.822131811,"NA","NA","Non","Endothelin-converting enzyme, partial [Ornithodoros moubata]"]
["JAW04922.1",12.61917976,12.42475544,"GO:0006099//tricarboxylic acid cycle;GO:0005975//carbohydrate metabolic process;GO:0006108//malate metabolic process","GO:0030060//L-malate dehydrogenase activity",null,"HsM5174541",490.3,{"v":2.5e-138,"d":"2.50E-138"},"KOG1494","NAD-dependent malate dehydrogenase",null,"C","Energy production and conversion","METABOLISM","K00026|1|1.1e-163|580.1|isc:IscW_ISCW003528|malate dehydrogenase [EC:1.1.1.37]","JAW04922.1","248887.294146529;","302301.384759801;",0.823308482,"NA","NA","Non","Malate dehydrogenase, partial [Ornithodoros moubata]"]
["JAV98837.1",14.81575755,14.62835481,"GO:0000086//G2/M transition of mitotic cell cycle;GO:0030705//cytoskeleton-dependent intracellular transport;GO:0051301//cell division;GO:0097711//ciliary basal body-plasma membrane docking;GO:0010389//regulation of G2/M transition of mitotic cell cycle;GO:0007017//microtubule-based process","GO:0005200//structural constituent of cytoskeleton;GO:0005198//structural molecule activity;GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0019904//protein domain specific binding;GO:0046982//protein heterodimerization activity","GO:0055037//recycling endosome;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0005874//microtubule;GO:0005737//cytoplasm;GO:0070062//extracellular exosome;GO:0043209//myelin sheath;GO:0005634//nucleus;GO:0015630//microtubule cytoskeleton;GO:0005881//cytoplasmic microtubule;GO:0005829//cytosol;GO:0045121//membrane raft","Hs17986283",898.7,{"v":4.1e-261,"d":"4.10E-261"},"KOG1376","Alpha tubulin",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K07374|1|8.0e-260|899.8|npr:108791406|tubulin alpha","JAV98837.1","2254310.70846305;","2718953.30960092;",0.829109754,"NA","NA","Non","Alpha tubulin, partial [Ornithodoros moubata]"]
["XP_064474492.1",12.01432236,11.82844121,null,"GO:0003924//GTPase activity;GO:0005525//GTP binding",null,"Hs4759020",338.2,{"v":1e-92,"d":"1.00E-92"},"KOG0092","GTPase Rab5/YPT51 and related small G protein superfamily GTPases",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K07889|1|2.3e-100|369.0|dpte:113790710|Ras-related protein Rab-5C!K07888|4|3.4e-99|365.2|pdam:113679723|Ras-related protein Rab-5B","XP_064474492.1","137096.619198976;","165102.597365303;",0.830372274,"NA","NA","Non","ras-related protein Rab-5B-like [Ornithodoros turicata]"]
["JAV98831.1",14.26545461,14.08175309,null,"GO:0016787//hydrolase activity;GO:0030246//carbohydrate binding",null,"Hs5453712",142.5,{"v":1.9e-33,"d":"1.90E-33"},"KOG3587","Galectin, galactose-binding lectin",null,"W","Extracellular structures","CELLULAR PROCESSES AND SIGNALING","K10091|1|1.5e-78|297.7|isc:IscW_ISCW008553|galectin-4","JAV98831.1","1305051.53269698;","1568224.45058749;",0.832184151,"NA","NA","Non","Galectin, partial [Ornithodoros moubata]"]
["JAR87695.1",9.407476905,9.225776149,"GO:0006094//gluconeogenesis","GO:0004613//phosphoenolpyruvate carboxykinase (GTP) activity;GO:0016301//kinase activity;GO:0005525//GTP binding",null,"Hs13653992",881.7,{"v":7.4e-256,"d":"7.40E-256"},"KOG3749","Phosphoenolpyruvate carboxykinase",null,"C","Energy production and conversion","METABOLISM","K01596|1|3.0e-268|928.3|lak:106158699|phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]","JAR87695.1","10155.555235091;","12179.1031454097;",0.833850827,"NA","NA","Non","phosphoenolpyruvate cytosolic, partial [Alectorobius mimon]"]
["JAW02608.1",9.022641757,8.844164885,"GO:0006012//galactose metabolic process","GO:0003978//UDP-glucose 4-epimerase activity;GO:0050662//coenzyme binding",null,"Hs4503891",460.7,{"v":2.3e-129,"d":"2.30E-129"},"KOG1371","UDP-glucose 4-epimerase/UDP-sulfoquinovose synthase",null,"M","Cell wall/membrane/envelope biogenesis","CELLULAR PROCESSES AND SIGNALING","K01784|1|2.8e-138|495.7|isc:IscW_ISCW022551|UDP-glucose 4-epimerase [EC:5.1.3.2]","JAW02608.1","6933.81110850006;","8288.64477045836;",0.836543404,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAV99318.1",11.08098629,10.90491789,"GO:0015991//ATP hydrolysis coupled proton transport","GO:0046933//proton-transporting ATP synthase activity, rotational mechanism;GO:0046961//proton-transporting ATPase activity, rotational mechanism","GO:0033180//proton-transporting V-type ATPase, V1 domain;GO:0016021//integral component of membrane",7303921,72.8,{"v":1.6e-12,"d":"1.60E-12"},"KOG3868","Vacuolar H+-ATPase V0 sector, accessory subunit S1 (Ac45)",null,"C","Energy production and conversion","METABOLISM","K03662|1|1.1e-45|188.3|isc:IscW_ISCW001149|V-type H+-transporting ATPase S1 subunit","JAV99318.1","54443.453330334;","64924.8865472891;",0.838560623,"NA","NA","Non","Vacuolar ATP synthase subunit S1, partial [Ornithodoros moubata]"]
["XP_064466313.1",11.29327038,11.12288168,"GO:0006457//protein folding","GO:0051082//unfolded protein binding;GO:0005524//ATP binding",null,"Hs21314627",1043.5,{"v":1.6e-304,"d":"1.60E-304"},"KOG0102","Molecular chaperones mortalin/PBP74/GRP75, HSP70 superfamily",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K04043|1|0.0e+00|1153.7|isc:IscW_ISCW017192|molecular chaperone DnaK","XP_064466313.1","67702.7228789393;","80279.5645882893;",0.843336947,"NA","NA","Non","stress-70 protein, mitochondrial-like [Ornithodoros turicata]"]
["JAW02818.1",12.56734242,12.40142266,"GO:0008152//metabolic process","GO:0004364//glutathione transferase activity",null,"Hs14745937",270,{"v":3.5e-72,"d":"3.50E-72"},"KOG1695","Glutathione S-transferase",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K00799|1|3.7e-109|398.3|isc:IscW_ISCW022157|glutathione S-transferase [EC:2.5.1.18]","JAW02818.1","243147.287067803;","287030.114846431;",0.847114203,"NA","NA","Non","Recombination repair protein 1, partial [Ornithodoros moubata]"]
["JAV99256.1",11.33415207,11.16873717,"GO:0007625//grooming behavior;GO:0032429//regulation of phospholipase A2 activity;GO:0006898//receptor-mediated endocytosis;GO:0007601//visual perception;GO:0008306//associative learning;GO:0002084//protein depalmitoylation;GO:0007269//neurotransmitter secretion;GO:0007040//lysosome organization;GO:0044257//cellular protein catabolic process;GO:0008344//adult locomotory behavior","GO:0008474//palmitoyl-(protein) hydrolase activity","GO:0005615//extracellular space;GO:0030425//dendrite;GO:0030424//axon;GO:0005764//lysosome;GO:0098793//presynapse;GO:0043025//neuronal cell body","Hs4506031",331.6,{"v":1.4e-90,"d":"1.40E-90"},"KOG2541","Palmitoyl protein thioesterase",null,"IO","Lipid transport and metabolism;Posttranslational modification, protein turnover, chaperones","METABOLISM;CELLULAR PROCESSES AND SIGNALING","K01074|1|1.3e-123|446.8|isc:IscW_ISCW016977|palmitoyl-protein thioesterase [EC:3.1.2.22]","JAV99256.1","70879.545211001;","83629.5382961974;",0.847541989,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["XP_064483629.1",11.65576924,11.49143343,{"$nulls":3},"Hs22060441",495,{"v":1.7e-139,"d":"1.70E-139"},"KOG3774","Uncharacterized conserved protein Lama",null,"T","Signal transduction mechanisms","CELLULAR PROCESSES AND SIGNALING","K04557|1|8.6e-91|338.6|egl:EGR_01732|septin 5","XP_064483629.1","97873.7268385203;","115354.957023874;",0.848457053,"NA","NA","Non","putative phospholipase B-like 2 [Ornithodoros turicata]"]
["JAR86938.1",9.944333568,9.784404347,"GO:0009072//aromatic amino acid family metabolic process","GO:0004334//fumarylacetoacetase activity",null,"Hs4557587",580.9,{"v":1.8e-165,"d":"1.80E-165"},"KOG2843","Fumarylacetoacetase",null,"G","Carbohydrate transport and metabolism","METABOLISM","K01555|1|3.6e-214|748.0|isc:IscW_ISCW020196|fumarylacetoacetase [EC:3.7.1.2]","JAR86938.1","17754.6786730228;","20833.8337705937;",0.852204106,"NA","NA","Non","fumarylacetoacetate hydrolase, partial [Alectorobius mimon]"]
["XP_064456721.1",10.34122121,10.18501238,"GO:0006564//L-serine biosynthetic process","GO:0051287//NAD binding;GO:0004617//phosphoglycerate dehydrogenase activity",null,"Hs14744596",463.8,{"v":4e-130,"d":"4.00E-130"},"KOG0068","D-3-phosphoglycerate dehydrogenase, D-isomer-specific 2-hydroxy acid dehydrogenase superfamily",null,"E","Amino acid transport and metabolism","METABOLISM","K00058|1|1.0e-197|693.7|isc:IscW_ISCW015967|D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]!K10460|2|6.0e-142|508.4|cmk:103176438|kelch-like protein 23","XP_064456721.1","26502.9779527005;","30983.8446474741;",0.855380546,"NA","NA","Non","D-3-phosphoglycerate dehydrogenase-like [Ornithodoros turicata]"]
["XP_064490262.1",10.27673163,10.12273643,null,"GO:0005524//ATP binding;GO:0032440//2-alkenal reductase [NAD(P)] activity",null,7301096,836.6,{"v":2.6e-242,"d":"2.60E-242"},"KOG0101","Molecular chaperones HSP70/HSC70, HSP70 superfamily",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K03283|1|1.8e-310|1068.5|isc:IscW_ISCW009157|heat shock 70kDa protein 1/2/6/8","XP_064490262.1","24902.822526662;","29048.7760864552;",0.857276136,"NA","NA","Non","heat shock protein 68-like [Ornithodoros turicata]"]
["JAW06477.1",11.06485672,10.91543244,"GO:0034314//Arp2/3 complex-mediated actin nucleation","GO:0005524//ATP binding","GO:0005885//Arp2/3 protein complex",7295163,746.1,{"v":3.2e-215,"d":"3.20E-215"},"KOG0678","Actin-related protein Arp2/3 complex, subunit Arp3",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K18584|1|1.8e-218|762.3|clec:106665195|actin-related protein 3","JAW06477.1","55018.9220707074;","63886.0762304411;",0.861203651,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["XP_064489598.1",10.25108581,10.10709904,"GO:0006457//protein folding;GO:0050821//protein stabilization;GO:0046677//response to antibiotic;GO:0007004//telomere maintenance via telomerase;GO:0031396//regulation of protein ubiquitination;GO:0051973//positive regulation of telomerase activity;GO:0051131//chaperone-mediated protein complex assembly;GO:0009409//response to cold;GO:0009408//response to heat;GO:0045040//protein import into mitochondrial outer membrane;GO:1905323//telomerase holoenzyme complex assembly","GO:0097718//disordered domain specific binding;GO:0051020//GTPase binding;GO:0016887//ATPase activity;GO:1990782//protein tyrosine kinase binding;GO:0070182//DNA polymerase binding;GO:0051082//unfolded protein binding;GO:0005524//ATP binding;GO:0042826//histone deacetylase binding;GO:0042802//identical protein binding;GO:0030235//nitric-oxide synthase regulator activity;GO:0023026//MHC class II protein complex binding;GO:0003723//RNA binding;GO:0030911//TPR domain binding","GO:0005737//cytoplasm;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0016020//membrane;GO:0043234//protein complex","Hs13129150",1215.7,0,"KOG0019","Molecular chaperone (HSP90 family)",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K04079|1|0.0e+00|1229.2|zne:110837294|molecular chaperone HtpG","XP_064489598.1","24516.4363724112;","28313.2680518987;",0.865899208,"NA","NA","Non","heat shock protein HSP 90-alpha-like [Ornithodoros turicata]"]
["XP_064477682.1",11.14602542,11.0029551,"GO:0006545//glycine biosynthetic process;GO:0035999//tetrahydrofolate interconversion","GO:0008168//methyltransferase activity;GO:0004372//glycine hydroxymethyltransferase activity;GO:0030170//pyridoxal phosphate binding",null,"Hs20070176",621.7,{"v":1e-177,"d":"1.00E-177"},"KOG2467","Glycine/serine hydroxymethyltransferase",null,"E","Amino acid transport and metabolism","METABOLISM","K00600|1|1.6e-234|815.8|isc:IscW_ISCW004246|glycine hydroxymethyltransferase [EC:2.1.2.1]","XP_064477682.1","60051.3374839735;","69287.8898780503;",0.86669312,"NA","NA","Non","serine hydroxymethyltransferase-like [Ornithodoros turicata] >XP_064477683.1 serine hydroxymethyltransferase-like [Ornithodoros turicata]"]
["JAV98819.1",13.44472897,13.3034356,"GO:0015031//protein transport;GO:0007264//small GTPase mediated signal transduction","GO:0005093//Rab GDP-dissociation inhibitor activity;GO:0005096//GTPase activator activity;GO:0016740//transferase activity","GO:0005737//cytoplasm",7297522,712.6,{"v":4.1e-205,"d":"4.10E-205"},"KOG1439","RAB proteins geranylgeranyltransferase component A (RAB escort protein)",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K17255|1|7.4e-218|760.4|dpx:DAPPUDRAFT_207615|Rab GDP dissociation inhibitor","JAV98819.1","599250.866888916;","690194.673582225;",0.868234557,"NA","NA","Non","Rab GDP dissociation inhibitor beta, partial [Ornithodoros moubata]"]
["XP_064470965.1",13.76538549,13.62708715,null,"GO:0005524//ATP binding",null,"Hs5729877",1134.4,0,"KOG0101","Molecular chaperones HSP70/HSC70, HSP70 superfamily",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K03283|1|0.0e+00|1150.2|soc:105201936|heat shock 70kDa protein 1/2/6/8","XP_064470965.1","828263.937037546;","951110.461923369;",0.870838846,"NA","NA","Non","heat shock 70 kDa protein cognate 4 [Ornithodoros turicata]"]
["XP_064456579.1",9.189611394,9.053837348,null,"GO:0016308//1-phosphatidylinositol-4-phosphate 5-kinase activity;GO:0016307//phosphatidylinositol phosphate kinase activity;GO:0005524//ATP binding",null,"Hs6857820",500,{"v":4e-141,"d":"4.00E-141"},"KOG0229","Phosphatidylinositol-4-phosphate 5-kinase",null,"T","Signal transduction mechanisms","CELLULAR PROCESSES AND SIGNALING","K00920|1|6.3e-174|614.4|isc:IscW_ISCW009432|1-phosphatidylinositol-5-phosphate 4-kinase [EC:2.7.1.149]","XP_064456579.1","8551.28931804981;","9794.84390431726;",0.873039877,"NA","NA","Non","phosphatidylinositol 5-phosphate 4-kinase type-2 alpha-like isoform X2 [Ornithodoros turicata]"]
["JAW00930.1",8.248506115,8.11383421,null,"GO:0004180//carboxypeptidase activity;GO:0008241//peptidyl-dipeptidase activity;GO:0046872//metal ion binding;GO:0008237//metallopeptidase activity","GO:0016021//integral component of membrane;GO:0016020//membrane","Hs4503273",516.5,{"v":6.4e-146,"d":"6.40E-146"},"KOG3690","Angiotensin I-converting enzymes - M2 family peptidases",null,"E","Amino acid transport and metabolism","METABOLISM","K01283|1|2.6e-187|659.4|isc:IscW_ISCW016862|peptidyl-dipeptidase A [EC:3.4.15.1]","JAW00930.1","3340.3611526679;","3821.91205915346;",0.87400262,"NA","NA","Non","Gnl1 1 protein Gnl1 2 protein, partial [Ornithodoros moubata]"]
["JAW02101.1",11.59764835,11.46338511,"GO:0090160//Golgi to lysosome transport;GO:0050821//protein stabilization;GO:0048102//autophagic cell death;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0043323//positive regulation of natural killer cell degranulation;GO:1902513//regulation of organelle transport along microtubule;GO:0008626//granzyme-mediated apoptotic signaling pathway;GO:0072594//establishment of protein localization to organelle;GO:0007283//spermatogenesis","GO:0019899//enzyme binding;GO:0019904//protein domain specific binding","GO:0008021//synaptic vesicle;GO:0005770//late endosome;GO:0009897//external side of plasma membrane;GO:0061474//phagolysosome membrane;GO:0030425//dendrite;GO:0044754//autolysosome;GO:0010008//endosome membrane;GO:0005737//cytoplasm;GO:0031982//vesicle;GO:0097208//alveolar lamellar body;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0044194//cytolytic granule;GO:0048471//perinuclear region of cytoplasm;GO:0043025//neuronal cell body;GO:0042383//sarcolemma;GO:0009986//cell surface;GO:0005886//plasma membrane;GO:0070062//extracellular exosome;GO:0042470//melanosome;GO:0005829//cytosol;GO:0045335//phagocytic vesicle;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0005771//multivesicular body","Hs7669501",67,{"v":4.1e-11,"d":"4.10E-11"},"KOG4818","Lysosomal-associated membrane protein",null,"R","General function prediction only","POORLY CHARACTERIZED","K06528|1|8.5e-20|101.3|lgi:LOTGIDRAFT_239003|lysosomal-associated membrane protein 1/2","JAW02101.1","95166.6749067634;","108841.540511667;",0.874359867,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["ABR23356.1",9.277975306,9.147882585,"GO:0002181//cytoplasmic translation;GO:0006412//translation","GO:0003735//structural constituent of ribosome;GO:0003723//RNA binding","GO:0005840//ribosome;GO:0022625//cytosolic large ribosomal subunit","Hs15431293",339.7,{"v":3.3e-93,"d":"3.30E-93"},"KOG1678","60s ribosomal protein L15",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K02877|1|1.4e-110|402.9|isc:IscW_ISCW008173|large subunit ribosomal protein L15e","ABR23356.1","9394.52718659707;","10699.7462635335;",0.878014016,"NA","NA","Non","60s ribosomal protein L15 [Ornithodoros parkeri] >XP_064476591.1 large ribosomal subunit protein eL15-like [Ornithodoros turicata]"]
["XP_064464227.1",9.736414199,9.609092939,{"$nulls":3},7295435,490.3,{"v":2.9e-138,"d":"2.90E-138"},"KOG2776","Metallopeptidase",null,"R","General function prediction only","POORLY CHARACTERIZED","K14813|1|1.5e-100|370.5|smm:Smp_150690.1|metalloprotease ARX1 [EC:3.-.-.-]!K01265|2|1.1e-26|125.2|cbr:CBG13686|methionyl aminopeptidase [EC:3.4.11.18]","XP_064464227.1","14899.6490651699;","16922.7508404466;",0.880450773,"NA","NA","Non","proliferation-associated protein 2G4-like [Ornithodoros turicata] >XP_064472059.1 proliferation-associated protein 2G4-like [Ornithodoros turicata]"]
["JAV99749.1",14.12630703,14.00205528,"GO:0007616//long-term memory","GO:0005215//transporter activity;GO:0008289//lipid binding","GO:0005654//nucleoplasm;GO:0005829//cytosol",7299467,121.3,{"v":1.2e-27,"d":"1.20E-27"},"KOG4015","Fatty acid-binding protein FABP",null,"I","Lipid transport and metabolism","METABOLISM","K08756|1|5.3e-31|137.9|dpte:113799670|fatty acid-binding protein 7, brain!K08752|3|3.2e-28|128.6|lak:106155900|fatty acid-binding protein 3, muscle and heart","JAV99749.1","1205078.5193821;","1364511.4726865;",0.883157484,"NA","NA","Non","Fatty acid-binding protein FABP, partial [Ornithodoros moubata]"]
["ACZ97552.1",10.42942695,10.30662484,null,"GO:0003746//translation elongation factor activity;GO:0003924//GTPase activity;GO:0005525//GTP binding",null,"Hs22052810",250.4,{"v":1.9e-66,"d":"1.90E-66"},"KOG0469","Elongation factor 2",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K03234|1|8.7e-75|283.5|isc:IscW_ISCW015380|elongation factor 2","ACZ97552.1","29930.2466294248;","33840.9521466588;",0.884438668,"NA","NA","Non","putative translational elongation factor-2, partial [Ornithodoros moubata]"]
["JAW04019.1",10.38550058,10.26496049,"GO:0006891//intra-Golgi vesicle-mediated transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0016192//vesicle-mediated transport;GO:0006886//intracellular protein transport","GO:0005198//structural molecule activity;GO:0016740//transferase activity","GO:0030663//COPI-coated vesicle membrane;GO:0030117//membrane coat;GO:0000139//Golgi membrane;GO:0030126//COPI vesicle coat","Hs4758032",1268.8,0,"KOG0276","Vesicle coat complex COPI, beta' subunit",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K17302|1|0.0e+00|1405.6|isc:IscW_ISCW022112|coatomer subunit beta'","JAW04019.1","28708.8435886321;","32386.6177030717;",0.88644155,"NA","NA","Non","hypothetical protein, partial [Ornithodoros moubata]"]
["JAT78781.1",10.88532756,10.76717892,"GO:0006810//transport",null,"GO:0016021//integral component of membrane","Hs5803149",241.1,{"v":1.2e-63,"d":"1.20E-63"},"KOG1692","Putative cargo transport protein EMP24 (p24 protein family)",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K20347|1|8.7e-78|293.5|isc:IscW_ISCW001359|p24 family protein beta-1","JAT78781.1","47438.0022357874;","53387.2677289256;",0.888563964,"NA","NA","Non","transmembrane emp24 domain trafficking protein 2, partial [Ornithodoros brasiliensis]"]
["JAW03828.1",10.98565042,10.86766902,null,"GO:0047964//glyoxylate reductase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0016618//hydroxypyruvate reductase activity;GO:0051287//NAD binding;GO:0030267//glyoxylate reductase (NADP) activity","GO:0005829//cytosol",7296684,274.6,{"v":2.1e-73,"d":"2.10E-73"},"KOG0069","Glyoxylate/hydroxypyruvate reductase (D-isomer-specific 2-hydroxy acid dehydrogenase superfamily)",null,"C","Energy production and conversion","METABOLISM","K00049|1|2.0e-143|512.7|isc:IscW_ISCW019963|glyoxylate/hydroxypyruvate reductase [EC:1.1.1.79 1.1.1.81]","JAW03828.1","52452.801259042;","59021.1076224877;",0.888712587,"NA","NA","Non","Glyoxylate-hydroxypyruvate reductase, partial [Ornithodoros moubata]"]
["JAW03003.1",11.32453135,11.21008096,null,"GO:0003746//translation elongation factor activity;GO:0004364//glutathione transferase activity",null,"Hs4503481_1",284.6,{"v":2.7e-76,"d":"2.70E-76"},"KOG0867","Glutathione S-transferase",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K03233|1|6.6e-155|551.2|phu:Phum_PHUM604750|elongation factor 1-gamma","JAW03003.1","73871.3954479427;","82828.8202709482;",0.891856183,"NA","NA","Non","Kazrin-A, partial [Ornithodoros moubata]"]
["JAW02862.1",9.433253144,9.319589726,{"$nulls":3},7299711,312.4,{"v":1.3e-84,"d":"1.30E-84"},"KOG2860","Uncharacterized conserved protein, contains TraB domain",null,"T","Signal transduction mechanisms","CELLULAR PROCESSES AND SIGNALING",null,"JAW02862.1","11154.4045487392;","12497.1155883922;",0.892558324,"NA","NA","Non","GI18784, partial [Ornithodoros moubata]"]
["XP_064476940.1",11.80044729,11.69174135,"GO:0045454//cell redox homeostasis;GO:0006662//glycerol ether metabolic process;GO:0034599//cellular response to oxidative stress","GO:0016853//isomerase activity;GO:0047134//protein-disulfide reductase activity;GO:0016671//oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor;GO:0015035//protein disulfide oxidoreductase activity;GO:0004791//thioredoxin-disulfide reductase activity","GO:0005737//cytoplasm",7297539,117.9,{"v":1.1e-26,"d":"1.10E-26"},"KOG0907","Thioredoxin",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K03671|1|8.2e-46|186.8|isc:IscW_ISCW006034|thioredoxin 1","XP_064476940.1","119580.055397608;","133311.968646934;",0.896994145,"NA","NA","Non","thioredoxin-2-like [Ornithodoros turicata]"]
["XP_064489224.1",10.89022974,10.78484701,null,"GO:0016740//transferase activity",null,7292935,395.2,{"v":8.6e-110,"d":"8.60E-110"},"KOG1422","Intracellular Cl- channel CLIC, contains GST domain",null,"P","Inorganic ion transport and metabolism","METABOLISM","K05022|1|1.7e-113|412.9|dpx:DAPPUDRAFT_300086|chloride intracellular channel protein 2","XP_064489224.1","48283.5889563362;","53649.6242031077;",0.899980003,"NA","NA","Non","chloride intracellular channel Clic-like [Ornithodoros turicata]"]
["JAW06487.1",12.78939699,12.68685016,"GO:0051383//kinetochore organization;GO:0042052//rhabdomere development;GO:0043277//apoptotic cell clearance;GO:0046716//muscle cell cellular homeostasis;GO:0009792//embryo development ending in birth or egg hatching;GO:0042981//regulation of apoptotic process;GO:0032880//regulation of protein localization;GO:0016062//adaptation of rhodopsin mediated signaling;GO:0016061//regulation of light-activated channel activity;GO:0016060//metarhodopsin inactivation;GO:0016477//cell migration;GO:0006468//protein phosphorylation;GO:0007608//sensory perception of smell;GO:0035071//salivary gland cell autophagic cell death;GO:0007605//sensory perception of sound;GO:0072499//photoreceptor cell axon guidance;GO:0051296//establishment of meiotic spindle orientation;GO:0030048//actin filament-based movement;GO:0016059//deactivation of rhodopsin mediated signaling;GO:0016056//rhodopsin mediated signaling pathway;GO:0051726//regulation of cell cycle;GO:0046331//lateral inhibition;GO:0007099//centriole replication;GO:2001259//positive regulation of cation channel activity","GO:0005509//calcium ion binding;GO:0032036//myosin heavy chain binding;GO:0031489//myosin V binding;GO:0070855//myosin VI head/neck binding","GO:0072686//mitotic spindle;GO:0097431//mitotic spindle pole;GO:0031476//myosin VI complex;GO:0031475//myosin V complex;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005813//centrosome;GO:0005814//centriole;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0016028//rhabdomere;GO:0005886//plasma membrane;GO:0071944//cell periphery;GO:0005829//cytosol;GO:0030496//midbody",7303485,296.6,{"v":2.4e-80,"d":"2.40E-80"},"KOG0027","Calmodulin and related proteins (EF-Hand superfamily)",null,"T","Signal transduction mechanisms","CELLULAR PROCESSES AND SIGNALING","K02183|1|1.0e-78|296.6|dme:Dmel_CG8472|calmodulin","JAW06487.1","323466.281259931;","358397.141869589;",0.902535884,"NA","NA","Non","Calmodulin 5, partial [Ornithodoros moubata] >XP_064489963.1 calmodulin isoform X2 [Ornithodoros turicata]"]
["JAW02649.1",13.27290755,13.17170842,"GO:0006164//purine nucleotide biosynthetic process","GO:0003937//IMP cyclohydrolase activity;GO:0004643//phosphoribosylaminoimidazolecarboxamide formyltransferase activity",null,7301227,846.3,{"v":3.2e-245,"d":"3.20E-245"},"KOG2555","AICAR transformylase/IMP cyclohydrolase/methylglyoxal synthase",null,"F","Nucleotide transport and metabolism","METABOLISM","K00602|1|6.8e-251|870.5|aag:5576840|phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]","JAW02649.1","525291.389490916;","581233.328669053;",0.903753043,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["XP_064476428.1",10.56217942,10.46136393,{"$nulls":3},"Hs20562210",188.7,{"v":2.3e-47,"d":"2.30E-47"},"KOG3528","FOG: PDZ domain",null,"S","Function unknown","POORLY CHARACTERIZED","K13358|1|1.1e-73|281.6|dpx:DAPPUDRAFT_192104|Na(+)/H(+) exchange regulatory cofactor NHE-RF2!K13365|2|1.3e-61|241.5|hro:HELRODRAFT_193300|Na(+)/H(+) exchange regulatory cofactor NHE-RF1","XP_064476428.1","34939.1735226756;","38645.260298154;",0.904099837,"NA","NA","Non","Na(+)/H(+) exchange regulatory cofactor NHE-RF1-like [Ornithodoros turicata]"]
["XP_064489201.1",11.10494257,11.01326698,null,"GO:0046872//metal ion binding;GO:0008270//zinc ion binding;GO:0004784//superoxide dismutase activity;GO:0005507//copper ion binding","GO:0005737//cytoplasm;GO:0005615//extracellular space","At1g08830",219.9,{"v":2.9e-57,"d":"2.90E-57"},"KOG0441","Cu2+/Zn2+ superoxide dismutase SOD1",null,"P","Inorganic ion transport and metabolism","METABOLISM","K04565|1|2.8e-71|271.9|isc:IscW_ISCW008219|superoxide dismutase, Cu-Zn family [EC:1.15.1.1]","XP_064489201.1","60673.7832643775;","66499.0253923812;",0.91240109,"NA","NA","Non","uncharacterized protein LOC135401025 [Ornithodoros turicata]"]
["JAV99390.1",12.19362353,12.1129433,"GO:0006606//protein import into nucleus;GO:0000054//ribosomal subunit export from nucleus;GO:0006913//nucleocytoplasmic transport;GO:0015031//protein transport","GO:0003924//GTPase activity;GO:0005525//GTP binding","GO:0005737//cytoplasm;GO:0005634//nucleus",7292609,411.8,{"v":7.5e-115,"d":"7.50E-115"},"KOG0096","GTPase Ran/TC4/GSP1 (nuclear protein transport pathway), small G protein superfamily",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K07936|1|2.2e-125|452.2|isc:IscW_ISCW023654|GTP-binding nuclear protein Ran","JAV99390.1","182215.130083258;","197525.61134225;",0.922488627,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAV98700.1",10.77091205,10.69460756,"GO:0006099//tricarboxylic acid cycle;GO:0006102//isocitrate metabolic process;GO:0030097//hemopoiesis","GO:0051287//NAD binding;GO:0000287//magnesium ion binding;GO:0004450//isocitrate dehydrogenase (NADP+) activity",null,"Hs14729950",671,{"v":1.3e-192,"d":"1.30E-192"},"KOG1526","NADP-dependent isocitrate dehydrogenase",null,"C","Energy production and conversion","METABOLISM","K00031|1|3.4e-209|731.5|isc:IscW_ISCW003975|isocitrate dehydrogenase [EC:1.1.1.42]","JAV98700.1","44117.3127186323;","47615.425296921;",0.926534047,"NA","NA","Non","Isocitrate dehydrogenase, partial [Ornithodoros moubata]"]
["JAR87346.1",11.40714808,11.33107382,"GO:0016998//cell wall macromolecule catabolic process;GO:0050830//defense response to Gram-positive bacterium;GO:0008152//metabolic process;GO:0050829//defense response to Gram-negative bacterium","GO:0003796//lysozyme activity","GO:0005615//extracellular space",{"$nulls":9},"K13915|1|1.8e-42|176.0|tut:107363126|lysozyme C [EC:3.2.1.17]!K01185|5|1.0e-32|143.7|der:6543837|lysozyme [EC:3.2.1.17]","JAR87346.1","83372.501794109;","89962.489950441;",0.926747379,"NA","NA","Non","lysozyme precursor, partial [Alectorobius mimon]"]
["JAW02965.1",11.83885519,11.76502996,"GO:0045454//cell redox homeostasis","GO:0004601//peroxidase activity;GO:0051920//peroxiredoxin activity","GO:0005623//cell","Hs5802974",311.2,{"v":1.4e-84,"d":"1.40E-84"},"KOG0852","Alkyl hydroperoxide reductase, thiol specific antioxidant and related enzymes",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K20011|1|1.3e-104|383.3|isc:IscW_ISCW015321|peroxiredoxin 3 [EC:1.11.1.15]","JAW02965.1","128673.048708509;","138531.800925168;",0.928834014,"NA","NA","Non","GD18448, partial [Ornithodoros moubata]"]
["XP_064488111.1",10.92057559,10.84873923,"GO:0008152//metabolic process;GO:0006635//fatty acid beta-oxidation","GO:0003985//acetyl-CoA C-acetyltransferase activity;GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups","GO:0005739//mitochondrion","Hs4557237",531.9,{"v":1.1e-150,"d":"1.10E-150"},"KOG1390","Acetyl-CoA acetyltransferase",null,"I","Lipid transport and metabolism","METABOLISM","K00626|1|1.6e-171|606.7|cfo:105249205|acetyl-CoA C-acetyltransferase [EC:2.3.1.9]","XP_064488111.1","51469.2194834037;","55302.6216415956;",0.930683175,"NA","NA","Non","acetyl-CoA acetyltransferase, mitochondrial-like [Ornithodoros turicata]"]
["ABR23349.1",9.019526547,8.9495254,"GO:0030490//maturation of SSU-rRNA;GO:0000028//ribosomal small subunit assembly;GO:0006412//translation","GO:0003735//structural constituent of ribosome;GO:0016787//hydrolase activity;GO:0003723//RNA binding","GO:0005840//ribosome;GO:0022627//cytosolic small ribosomal subunit","Hs4506715",114.4,{"v":7.1e-26,"d":"7.10E-26"},"KOG3502","40S ribosomal protein S28",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K02979|1|3.6e-25|117.5|dre:406307|small subunit ribosomal protein S28e","ABR23349.1","7704.23456500007;","8262.86407646359;",0.932392751,"NA","NA","Non","40S ribosomal protein S28 [Ornithodoros parkeri]"]
["JAW06412.1",9.840411657,9.77247657,"GO:0016192//vesicle-mediated transport;GO:0006886//intracellular protein transport;GO:0048268//clathrin coat assembly","GO:0032051//clathrin light chain binding;GO:0005198//structural molecule activity","GO:0071439//clathrin complex;GO:0030130//clathrin coat of trans-Golgi network vesicle;GO:0030132//clathrin coat of coated pit",7293138,1096.6,0,"KOG0985","Vesicle coat protein clathrin, heavy chain",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K04646|1|0.0e+00|1205.3|zne:110826899|clathrin heavy chain","JAW06412.1","17544.1628123862;","18777.4442966583;",0.934321121,"NA","NA","Non","Clathrin heavy chain 1, partial [Ornithodoros moubata]"]
["XP_064484593.1",12.71141143,12.64920757,"GO:0006888//ER to Golgi vesicle-mediated transport","GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0005789//endoplasmic reticulum membrane;GO:0000139//Golgi membrane","Hs4758988",357.1,{"v":2e-98,"d":"2.00E-98"},"KOG0084","GTPase Rab1/YPT1, small G protein superfamily, and related GTP-binding proteins",null,"TU","Signal transduction mechanisms;Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING;CELLULAR PROCESSES AND SIGNALING","K07874|1|1.3e-100|369.8|myi:110459588|Ras-related protein Rab-1A","XP_064484593.1","311516.496702175;","331509.394544459;",0.939691308,"NA","NA","Non","ras-related protein Rab-1A [Ornithodoros turicata]"]
["JAT78834.1",10.44331174,10.38399272,"GO:0007017//microtubule-based process","GO:0005200//structural constituent of cytoskeleton;GO:0003924//GTPase activity;GO:0005525//GTP binding","GO:0005737//cytoplasm;GO:0070062//extracellular exosome;GO:0043209//myelin sheath;GO:0005634//nucleus;GO:0005881//cytoplasmic microtubule;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0005874//microtubule;GO:0055037//recycling endosome","Hs17986283",900.6,{"v":1.1e-261,"d":"1.10E-261"},"KOG1376","Alpha tubulin",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K07374|1|1.7e-260|902.1|ipu:108255233|tubulin alpha","JAT78834.1","32337.8199309873;","34314.1037070333;",0.942406079,"NA","NA","Non","alpha tubulin, partial [Ornithodoros brasiliensis]"]
["JAV99242.1",11.17692906,11.11914514,"GO:0007165//signal transduction",null,"GO:0005737//cytoplasm",7291298,359.8,{"v":6e-99,"d":"6.00E-99"},"KOG2931","Differentiation-related gene 1 protein (NDR1 protein), related proteins",null,"S","Function unknown","POORLY CHARACTERIZED","K18266|1|1.7e-64|250.8|amex:103037827|protein NDRG1","JAV99242.1","67450.2212887754;","71462.5672420794;",0.943853879,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["XP_064473000.1",10.19711083,10.14298583,null,"GO:0004869//cysteine-type endopeptidase inhibitor activity","GO:0005622//intracellular",{"$nulls":9},"K13907|1|3.9e-18|94.7|xma:102222512|cystatin-A/B","XP_064473000.1","25412.2298044926;","26825.5703572596;",0.947313681,"NA","NA","Non","cystatin-B-like [Ornithodoros turicata]"]
["JAW05908.1",13.09083122,13.03986041,"GO:0006096//glycolytic process","GO:0004332//fructose-bisphosphate aldolase activity",null,7301454,510.8,{"v":1.9e-144,"d":"1.90E-144"},"KOG1557","Fructose-biphosphate aldolase",null,"G","Carbohydrate transport and metabolism","METABOLISM","K01623|1|1.6e-157|559.7|haw:110380063|fructose-bisphosphate aldolase, class I [EC:4.1.2.13]","JAW05908.1","460404.352948804;","484479.900618108;",0.950306406,"NA","NA","Non","Fructose-bisphosphate aldolase, partial [Ornithodoros moubata]"]
["XP_064458520.1",9.936000795,9.888752295,"GO:0030433//ubiquitin-dependent ERAD pathway","GO:0031625//ubiquitin protein ligase binding","GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum","Hs6005721",449.9,{"v":4e-126,"d":"4.00E-126"},"KOG2962","Prohibitin-related membrane protease subunits",null,"R","General function prediction only","POORLY CHARACTERIZED","K17497|1|9.0e-49|198.4|ovi:T265_12075|phosphomannomutase [EC:5.4.2.8]","XP_064458520.1","19707.4555057902;","20660.9514696876;",0.953850336,"NA","NA","Non","erlin-1-like [Ornithodoros turicata] >XP_064458521.1 erlin-1-like [Ornithodoros turicata] >XP_064458522.1 erlin-1-like [Ornithodoros turicata] >XP_064458523.1 erlin-1-like [Ornithodoros turicata] >XP_064458524.1 erlin-1-like [Ornithodoros turicata]"]
["JAW05810.1",9.055734898,9.013694665,"GO:0007034//vacuolar transport",null,"GO:0005622//intracellular","Hs14721561",223.8,{"v":2.8e-58,"d":"2.80E-58"},"KOG3231","Predicted assembly/vacuolar sorting protein",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K12192|1|8.0e-85|317.4|isc:IscW_ISCW019894|charged multivesicular body protein 2B","JAW05810.1","8214.81626883144;","8567.53121902526;",0.958831203,"NA","NA","Non","Vacuolar assembly-sorting protein DID4, partial [Ornithodoros moubata]"]
["JAV98949.1",10.30984979,10.27207361,"GO:0006546//glycine catabolic process","GO:0004047//aminomethyltransferase activity;GO:0008483//transaminase activity","GO:0005739//mitochondrion","CE09620",417.2,{"v":3.3e-116,"d":"3.30E-116"},"KOG2770","Aminomethyl transferase",null,"E","Amino acid transport and metabolism","METABOLISM","K00605|1|3.1e-146|522.3|isc:IscW_ISCW001092|aminomethyltransferase [EC:2.1.2.10]","JAV98949.1","28913.7809257651;","30026.9259468449;",0.962928439,"NA","NA","Non","Aminomethyltransferase, partial [Ornithodoros moubata]"]
["JAV99904.1",9.28427672,9.250250848,"GO:0060169//negative regulation of adenosine receptor signaling pathway;GO:0042110//T cell activation;GO:0006154//adenosine catabolic process;GO:0043103//hypoxanthine salvage;GO:0046103//inosine biosynthetic process;GO:0009168//purine ribonucleoside monophosphate biosynthetic process","GO:0004000//adenosine deaminase activity","GO:0009897//external side of plasma membrane;GO:0005829//cytosol","Hs4557249",274.6,{"v":2.3e-73,"d":"2.30E-73"},"KOG1097","Adenine deaminase/adenosine deaminase",null,"F","Nucleotide transport and metabolism","METABOLISM","K01488|1|1.5e-78|297.4|phyp:113530327|adenosine deaminase [EC:3.5.4.4]","JAV99904.1","10407.1760057543;","10767.3826724845;",0.966546497,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW02731.1",13.37142182,13.33772577,"GO:0042744//hydrogen peroxide catabolic process;GO:0006979//response to oxidative stress","GO:0046872//metal ion binding;GO:0020037//heme binding;GO:0004096//catalase activity",null,"Hs4557014",708.4,{"v":8.7e-204,"d":"8.70E-204"},"KOG0047","Catalase",null,"P","Inorganic ion transport and metabolism","METABOLISM","K03781|1|4.0e-212|741.5|phu:Phum_PHUM336860|catalase [EC:1.11.1.6]","JAW02731.1","620155.649702483;","641408.501475659;",0.966865341,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["WNM64282.1",10.19007614,10.1577688,null,"GO:0016787//hydrolase activity",null,7295215,58.5,{"v":4.2e-08,"d":"4.20E-08"},"KOG1217","Fibrillins and related proteins containing Ca2+-binding EGF-like domains",null,"T","Signal transduction mechanisms","CELLULAR PROCESSES AND SIGNALING","K02599|1|2.1e-07|61.6|aplc:110983541|Notch 1!K17307|2|2.8e-07|61.2|cqu:CpipJ_CPIJ017419|fibulin 1/2","WNM64282.1","25790.6885832382;","26637.5229422389;",0.968208967,"NA","NA","Non","Om86 protein [Ornithodoros moubata]"]
["JAW02889.1",10.43514661,10.40439334,"GO:0006490//oligosaccharide-lipid intermediate biosynthetic process;GO:0033577//protein glycosylation in endoplasmic reticulum","GO:0004377//GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity;GO:0016757//transferase activity, transferring glycosyl groups","GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane",7296469,263.8,{"v":3.7e-70,"d":"3.70E-70"},"KOG1387","Glycosyltransferase",null,"M","Cell wall/membrane/envelope biogenesis","CELLULAR PROCESSES AND SIGNALING","K03844|1|1.7e-102|376.7|isc:IscW_ISCW005363|alpha-1,2-mannosyltransferase [EC:2.4.1.131]","JAW02889.1","33004.3066864199;","34035.0656073252;",0.969714796,"NA","NA","Non","26S proteasome non-ATPase regulatory subunit 11, partial [Ornithodoros moubata]"]
["JAV98804.1",9.381082559,9.351121244,"GO:0033198//response to ATP","GO:0001614//purinergic nucleotide receptor activity;GO:0004931//extracellularly ATP-gated cation channel activity","GO:0005887//integral component of plasma membrane;GO:0098794//postsynapse",{"$nulls":9},"K05218|1|1.2e-46|190.7|dpx:DAPPUDRAFT_206200|P2X purinoceptor 4","JAV98804.1","11511.7236594711;","11861.8489581329;",0.970483076,"NA","NA","Non","P2X receptor, partial [Ornithodoros moubata]"]
["JAW00653.1",11.42439508,11.39627023,null,"GO:0016787//hydrolase activity;GO:0045134//uridine-diphosphatase activity;GO:0047631//ADP-ribose diphosphatase activity;GO:0019144//ADP-sugar diphosphatase activity",null,"Hs7657403",70.1,{"v":2.3e-12,"d":"2.30E-12"},"KOG3041","Nucleoside diphosphate-sugar hydrolase of the MutT (NUDIX) family",null,"L","Replication, recombination and repair","INFORMATION STORAGE AND PROCESSING","K13987|1|5.9e-27|124.0|isc:IscW_ISCW021976|ADP-sugar pyrophosphatase / 8-oxo-dGDP phosphatase / ADP-D-ribose pyrophosphorylase [EC:3.6.1.13 3.6.1.58 3.6.1.- 2.7.7.96]","JAW00653.1","88989.1941427542;","91527.5297270645;",0.972266972,"NA","NA","Non","AP-1 complex subunit sigma-2, partial [Ornithodoros moubata]"]
["JAT79031.1",9.677160848,9.651966152,"GO:0006879//cellular iron ion homeostasis;GO:0008152//metabolic process;GO:0010040//response to iron(II) ion","GO:0051539//4 iron, 4 sulfur cluster binding;GO:0003994//aconitate hydratase activity","GO:0005737//cytoplasm",7300911,276.2,{"v":3.9e-74,"d":"3.90E-74"},"KOG0452","RNA-binding translational regulator IRP (aconitase superfamily)",null,"AJ","RNA processing and modification;Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING;INFORMATION STORAGE AND PROCESSING","K01681|1|5.6e-84|314.3|isc:IscW_ISCW013457|aconitate hydratase [EC:4.2.1.3]","JAT79031.1","15552.3363150935;","15949.1505142913;",0.975120042,"NA","NA","Non","cytoplasmic aconitate hydratase, partial [Ornithodoros brasiliensis]"]
["XP_064482283.1",9.68256601,9.660537955,"GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination","GO:0004843//thiol-dependent ubiquitin-specific protease activity;GO:0043130//ubiquitin binding","GO:0005737//cytoplasm;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005622//intracellular;GO:0005829//cytosol","Hs5174741",263.1,{"v":4.4e-70,"d":"4.40E-70"},"KOG1415","Ubiquitin C-terminal hydrolase UCHL1",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K05609|1|6.6e-69|264.6|lav:100663882|ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]","XP_064482283.1","15686.2208791804;","16035.5916647443;",0.978212791,"NA","NA","Non","ubiquitin carboxyl-terminal hydrolase isozyme L3-like isoform X2 [Ornithodoros turicata]"]
["ATY50246.1",11.61358565,11.59601368,null,"GO:0003746//translation elongation factor activity;GO:0003924//GTPase activity;GO:0005525//GTP binding","GO:0005737//cytoplasm",7303554,733.8,{"v":1.6e-211,"d":"1.60E-211"},"KOG0052","Translation elongation factor EF-1 alpha/Tu",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K03231|1|2.8e-235|818.1|isc:IscW_ISCW020299|elongation factor 1-alpha","ATY50246.1","108663.765720523;","110590.078169077;",0.982581507,"NA","NA","Non","elongation factor 1-alpha, partial [Alectorobius yumatensis]"]
["XP_064457211.1",11.35690293,11.34464521,"GO:0045454//cell redox homeostasis","GO:0051920//peroxiredoxin activity","GO:0005623//cell",7295884,292,{"v":8.6e-79,"d":"8.60E-79"},"KOG0854","Alkyl hydroperoxide reductase, thiol specific antioxidant and related enzymes",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K11188|1|3.1e-84|315.5|zne:110833882|peroxiredoxin 6, 1-Cys peroxiredoxin [EC:1.11.1.7 1.11.1.15 3.1.1.-]","XP_064457211.1","84511.6950148483;","85553.9912773361;",0.987817094,"NA","NA","Non","peroxiredoxin-6-like [Ornithodoros turicata] >XP_064464092.1 peroxiredoxin-6-like isoform X1 [Ornithodoros turicata]"]
["JAW02213.1",10.85032247,10.83985792,"GO:0006189//'de novo' IMP biosynthetic process","GO:0004639//phosphoribosylaminoimidazolesuccinocarboxamide synthase activity",null,"Hs5453539",122.9,{"v":6e-28,"d":"6.00E-28"},"KOG2835","Phosphoribosylamidoimidazole-succinocarboxamide synthase",null,"F","Nucleotide transport and metabolism","METABOLISM","K01587|1|4.9e-33|145.2|crg:105333392|phosphoribosylaminoimidazole carboxylase / phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:4.1.1.21 6.3.2.6]","JAW02213.1","51014.1294081083;","51550.7724096514;",0.98959001,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAV98684.1",10.68019351,10.68531388,"GO:0015991//ATP hydrolysis coupled proton transport","GO:0015078//hydrogen ion transmembrane transporter activity","GO:0033179//proton-transporting V-type ATPase, V0 domain",7290447,608.2,{"v":8.6e-174,"d":"8.60E-174"},"KOG2957","Vacuolar H+-ATPase V0 sector, subunit d",null,"C","Energy production and conversion","METABOLISM","K02146|1|2.0e-173|612.5|aag:110675318|V-type H+-transporting ATPase subunit d","JAV98684.1","43709.1996833674;","43485.9647235241;",1.005133494,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAV99973.1",9.576658931,9.583060927,"GO:0051603//proteolysis involved in cellular protein catabolic process","GO:0004298//threonine-type endopeptidase activity","GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005839//proteasome core complex",7294336,352.4,{"v":6.6e-97,"d":"6.60E-97"},"KOG0173","20S proteasome, regulatory subunit beta type PSMB7/PSMB10/PUP1",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K02739|1|2.9e-116|422.2|isc:IscW_ISCW006222|20S proteasome subunit beta 2 [EC:3.4.25.1]","JAV99973.1","14516.7861889214;","14424.1466389303;",1.006422532,"NA","NA","Non","Proteasome subunit beta type, partial [Ornithodoros moubata]"]
["JAW05906.1",8.230367843,8.239312697,"GO:0006281//DNA repair;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0006289//nucleotide-excision repair","GO:0003676//nucleic acid binding;GO:0003684//damaged DNA binding","GO:0005634//nucleus;GO:0031461//cullin-RING ubiquitin ligase complex","Hs13435359",1669.8,0,"KOG1897","Damage-specific DNA binding complex, subunit DDB1",null,"L","Replication, recombination and repair","INFORMATION STORAGE AND PROCESSING","K10610|1|0.0e+00|2009.6|isc:IscW_ISCW004025|DNA damage-binding protein 1","JAW05906.1","3786.93663945773;","3753.21409221447;",1.008984978,"NA","NA","Non","DNA repair protein xp-E, partial [Ornithodoros moubata]"]
["JAW03916.1",15.12935719,15.13936276,"GO:0005975//carbohydrate metabolic process","GO:0004565//beta-galactosidase activity","GO:0005764//lysosome;GO:0005773//vacuole","Hs10834966",511.9,{"v":1.5e-144,"d":"1.50E-144"},"KOG0496","Beta-galactosidase",null,"G","Carbohydrate transport and metabolism","METABOLISM","K12309|1|5.2e-228|794.7|isc:IscW_ISCW019676|beta-galactosidase [EC:3.2.1.23]","JAW03916.1","3757869.59593887;","3720457.445727;",1.010055793,"NA","NA","Non","Beta-galactosidase, partial [Ornithodoros moubata]"]
["JAV98966.1",10.97827469,10.98872437,"GO:0006457//protein folding;GO:0006458//'de novo' protein folding;GO:1904851//positive regulation of establishment of protein localization to telomere;GO:0050821//protein stabilization;GO:1904871//positive regulation of protein localization to Cajal body;GO:1901998//toxin transport;GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0007339//binding of sperm to zona pellucida;GO:0061077//chaperone-mediated protein folding;GO:1904874//positive regulation of telomerase RNA localization to Cajal body;GO:0009615//response to virus","GO:0048487//beta-tubulin binding;GO:0051082//unfolded protein binding;GO:0048027//mRNA 5'-UTR binding;GO:0003730//mRNA 3'-UTR binding;GO:0005524//ATP binding;GO:0031681//G-protein beta-subunit binding;GO:0044183//protein binding involved in protein folding","GO:0005874//microtubule;GO:0005737//cytoplasm;GO:0070062//extracellular exosome;GO:0005730//nucleolus;GO:0043209//myelin sheath;GO:0005813//centrosome;GO:0005832//chaperonin-containing T-complex;GO:0044297//cell body;GO:0002199//zona pellucida receptor complex","Hs16159222",852.8,{"v":3.1e-247,"d":"3.10E-247"},"KOG0357","Chaperonin complex component, TCP-1 epsilon subunit (CCT5)",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K09497|1|4.5e-249|864.4|zne:110830053|T-complex protein 1 subunit epsilon","JAV98966.1","59202.8146984228;","58587.385358811;",1.010504468,"NA","NA","Non","Pc16g03900 protein, partial [Ornithodoros moubata]"]
["JAV98683.1",10.68873583,10.70625253,null,null,"GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane",7300800,280,{"v":1.1e-74,"d":"1.10E-74"},"KOG1854","Mitochondrial inner membrane protein (mitofilin)",null,"M","Cell wall/membrane/envelope biogenesis","CELLULAR PROCESSES AND SIGNALING","K17785|1|9.6e-156|554.7|isc:IscW_ISCW010047|mitofilin","JAV98683.1","44634.0601589676;","43859.0265307425;",1.017671018,"NA","NA","Non","Transmembrane protein, partial [Ornithodoros moubata]"]
["JAT78669.1",9.60909801,9.627698218,null,"GO:0004198//calcium-dependent cysteine-type endopeptidase activity;GO:0005509//calcium ion binding","GO:0005622//intracellular","CE29565",231.1,{"v":1.4e-60,"d":"1.40E-60"},"KOG0045","Cytosolic Ca2+-dependent cysteine protease (calpain), large subunit (EF-Hand protein superfamily)",null,"OT","Posttranslational modification, protein turnover, chaperones;Signal transduction mechanisms","CELLULAR PROCESSES AND SIGNALING;CELLULAR PROCESSES AND SIGNALING","K08585|1|9.1e-63|243.8|api:100166784|calpain, invertebrate [EC:3.4.22.-]","JAT78669.1","15179.4560598515;","14899.7246175632;",1.018774269,"NA","NA","Non","calpain isoform, partial [Ornithodoros brasiliensis]"]
["JAV99025.1",9.000422937,9.021704248,"GO:0097194//execution phase of apoptosis","GO:0004197//cysteine-type endopeptidase activity;GO:0097200//cysteine-type endopeptidase activity involved in execution phase of apoptosis","GO:0005737//cytoplasm","Hs15718698",240,{"v":5.3e-63,"d":"5.30E-63"},"KOG3573","Caspase, apoptotic cysteine protease",null,"D","Cell cycle control, cell division, chromosome partitioning","CELLULAR PROCESSES AND SIGNALING","K04397|1|4.0e-74|282.3|isc:IscW_ISCW013172|caspase 7 [EC:3.4.22.60]","JAV99025.1","8280.87773137431;","8106.51174994239;",1.021509373,"NA","NA","Non","Caspase-1, partial [Ornithodoros moubata]"]
["JAW02657.1",13.75211156,13.77814397,"GO:0006457//protein folding;GO:0045454//cell redox homeostasis;GO:0034976//response to endoplasmic reticulum stress","GO:0003756//protein disulfide isomerase activity;GO:0016757//transferase activity, transferring glycosyl groups","GO:0005783//endoplasmic reticulum",7303555,437.2,{"v":2.8e-122,"d":"2.80E-122"},"KOG0190","Protein disulfide isomerase (prolyl 4-hydroxylase beta subunit)",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K08056|1|1.6e-157|559.7|isc:IscW_ISCW016161|protein disulfide-isomerase A3 [EC:5.3.4.1]","JAW02657.1","963322.927125199;","938568.912550621;",1.026374211,"NA","NA","Non","Phosphatidylinositol-specific phospholipase C X domain-containing protein, partial [Ornithodoros moubata]"]
["XP_064477664.1",10.18996227,10.2163227,"GO:0006099//tricarboxylic acid cycle","GO:0003994//aconitate hydratase activity;GO:0046872//metal ion binding;GO:0051539//4 iron, 4 sulfur cluster binding","GO:0005739//mitochondrion","CE25005",1208,0,"KOG0453","Aconitase/homoaconitase (aconitase superfamily)",null,"CE","Energy production and conversion;Amino acid transport and metabolism","METABOLISM;METABOLISM","K01681|1|0.0e+00|1269.6|nvi:100124130|aconitate hydratase [EC:4.2.1.3]","XP_064477664.1","27345.9222147476;","26634.489919416;",1.026710941,"NA","NA","Non","probable aconitate hydratase, mitochondrial [Ornithodoros turicata]"]
["XP_064486785.1",9.303871928,9.330844621,"GO:0006904//vesicle docking involved in exocytosis;GO:0007295//growth of a germarium-derived egg chamber;GO:0032869//cellular response to insulin stimulus;GO:0017157//regulation of exocytosis;GO:0009306//protein secretion;GO:0045175//basal protein localization;GO:0032482//Rab protein signal transduction;GO:0046331//lateral inhibition;GO:0061864//basement membrane constituent secretion;GO:0110010//basolateral protein secretion;GO:0016192//vesicle-mediated transport;GO:0110011//regulation of basement membrane organization","GO:0003924//GTPase activity;GO:0005525//GTP binding","GO:0055037//recycling endosome;GO:0045202//synapse;GO:0032593//insulin-responsive compartment;GO:0005737//cytoplasm;GO:0031982//vesicle;GO:0045178//basal part of cell;GO:0043025//neuronal cell body;GO:0005794//Golgi apparatus;GO:0016328//lateral plasma membrane;GO:0031254//cell trailing edge",7295615,323.9,{"v":1.9e-88,"d":"1.90E-88"},"KOG0078","GTP-binding protein SEC4, small G protein superfamily, and related Ras family GTP-binding proteins",null,"TU","Signal transduction mechanisms;Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING;CELLULAR PROCESSES AND SIGNALING","K07903|1|1.5e-88|329.7|dpte:113798894|Ras-related protein Rab-10","XP_064486785.1","11280.6553438212;","10980.4525257942;",1.027339749,"NA","NA","Non","ras-related protein Rab-10-like [Ornithodoros turicata]"]
["JAW06744.1",11.8501433,11.8800482,"GO:0016331//morphogenesis of embryonic epithelium;GO:0030324//lung development;GO:0014032//neural crest cell development;GO:0031016//pancreas development;GO:0031076//embryonic camera-type eye development;GO:0010628//positive regulation of gene expression;GO:0060324//face development;GO:0021915//neural tube development;GO:0042574//retinal metabolic process;GO:0048384//retinoic acid receptor signaling pathway;GO:0001568//blood vessel development;GO:0048566//embryonic digestive tract development;GO:0043065//positive regulation of apoptotic process;GO:0042904//9-cis-retinoic acid biosynthetic process;GO:0035799//ureter maturation;GO:0008284//positive regulation of cell proliferation;GO:0008285//negative regulation of cell proliferation;GO:0034097//response to cytokine;GO:0030182//neuron differentiation;GO:0003007//heart morphogenesis;GO:0035115//embryonic forelimb morphogenesis;GO:0009954//proximal/distal pattern formation;GO:0009952//anterior/posterior pattern specification;GO:0048738//cardiac muscle tissue development;GO:0071300//cellular response to retinoic acid;GO:0030900//forebrain development;GO:0030902//hindbrain development;GO:0009855//determination of bilateral symmetry;GO:0001936//regulation of endothelial cell proliferation","GO:0016491//oxidoreductase activity;GO:0004028//3-chloroallyl aldehyde dehydrogenase activity;GO:0004029//aldehyde dehydrogenase (NAD) activity;GO:0001758//retinal dehydrogenase activity","GO:0005737//cytoplasm","Hs10835045",667.5,{"v":1.7e-191,"d":"1.70E-191"},"KOG2450","Aldehyde dehydrogenase",null,"C","Energy production and conversion","METABOLISM","K07249|1|4.0e-196|688.3|sko:100366585|retinal dehydrogenase [EC:1.2.1.36]!K00128|3|3.5e-192|675.2|tut:107368714|aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]","JAW06744.1","144357.507948688;","140104.423258849;",1.030356534,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAV99007.1",10.22888073,10.25939173,null,"GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding",null,"CE04883",152.5,{"v":9.3e-37,"d":"9.30E-37"},"KOG3714","Meprin A metalloprotease",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K01395|1|1.2e-36|157.5|obi:106872756|meprin A [EC:3.4.24.18]!K08076|2|4.0e-35|152.5|cel:CELE_T04G9.2|astacin [EC:3.4.24.21]!K08606|3|4.0e-35|152.5|myi:110442536|meprin B [EC:3.4.24.63]","JAV99007.1","28549.4152590287;","27691.4983732014;",1.030981237,"NA","NA","Non","Metalloendopeptidase, partial [Ornithodoros moubata]"]
["XP_064474510.1",11.52950206,11.56280136,null,"GO:0051015//actin filament binding",null,7296888,555.8,{"v":1.1e-157,"d":"1.10E-157"},"KOG0443","Actin regulatory proteins (gelsolin/villin family)",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K05768|1|0.0e+00|1161.7|isc:IscW_ISCW007199|gelsolin","XP_064474510.1","105114.063133219;","101671.474558299;",1.033859926,"NA","NA","Non","gelsolin, cytoplasmic-like isoform X1 [Ornithodoros turicata]"]
["JAV98707.1",13.18816828,13.23063834,"GO:0051603//proteolysis involved in cellular protein catabolic process","GO:0004185//serine-type carboxypeptidase activity",null,"Hs4505989",381.7,{"v":1.8e-105,"d":"1.80E-105"},"KOG1282","Serine carboxypeptidases (lysosomal cathepsin A)",null,"OE","Posttranslational modification, protein turnover, chaperones;Amino acid transport and metabolism","CELLULAR PROCESSES AND SIGNALING;METABOLISM","K13289|1|2.0e-120|436.8|spu:594128|cathepsin A (carboxypeptidase C) [EC:3.4.16.5]","JAV98707.1","557177.05541161;","534009.163316287;",1.043384821,"NA","NA","Non","Carboxypeptidase, partial [Ornithodoros moubata]"]
["JAW01268.1",10.84625455,10.89287347,null,"GO:0004725//protein tyrosine phosphatase activity;GO:0005509//calcium ion binding",null,7292157,893.6,{"v":1.9e-259,"d":"1.90E-259"},"KOG0040","Ca2+-binding actin-bundling protein (spectrin), alpha chain (EF-Hand protein superfamily)",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K06114|1|0.0e+00|1112.8|isc:IscW_ISCW000012|spectrin alpha","JAW01268.1","53791.6468999109;","51341.4938348704;",1.047722668,"NA","NA","Non","Calcium-binding protein, partial [Ornithodoros moubata]"]
["JAW04414.1",10.23917802,10.2871806,"GO:0034314//Arp2/3 complex-mediated actin nucleation","GO:0003779//actin binding","GO:0005737//cytoplasm;GO:0005885//Arp2/3 protein complex","Hs5031597",246.1,{"v":4.4e-65,"d":"4.40E-65"},"KOG3155","Actin-related protein Arp2/3 complex, subunit ARPC3",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K05756|1|2.3e-85|318.9|isc:IscW_ISCW022587|actin related protein 2/3 complex, subunit 3","JAW04414.1","29353.8970695508;","27978.1190299667;",1.049173357,"NA","NA","Non","Actin-related protein 2-3 complex subunit 3 Arp2-3 complex 21 kDa subunit, partial [Ornithodoros moubata]"]
["XP_064482455.1",8.918979318,8.968064377,"GO:1990830//cellular response to leukemia inhibitory factor;GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006412//translation","GO:0016787//hydrolase activity;GO:0003735//structural constituent of ribosome;GO:0003723//RNA binding","GO:0005840//ribosome;GO:0070062//extracellular exosome;GO:0016020//membrane;GO:0031012//extracellular matrix;GO:0005925//focal adhesion;GO:0022627//cytosolic small ribosomal subunit","Hs4506691",257.7,{"v":1.2e-68,"d":"1.20E-68"},"KOG1753","40S ribosomal protein S16",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K02960|1|1.1e-67|260.0|salp:111982669|small subunit ribosomal protein S16e","XP_064482455.1","7848.39535659363;","7472.4583288123;",1.050309685,"NA","NA","Non","small ribosomal subunit protein uS9 [Ornithodoros turicata]"]
["XP_064461229.1",11.82488822,11.87495051,null,"GO:0019904//protein domain specific binding",null,7300360,444.5,{"v":1.2e-124,"d":"1.20E-124"},"KOG0841","Multifunctional chaperone (14-3-3 family)",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K06630|1|2.4e-136|488.8|isc:IscW_ISCW011376|14-3-3 protein epsilon","XP_064461229.1","143623.491698212;","136610.380966853;",1.051336587,"NA","NA","Non","14-3-3 protein epsilon [Ornithodoros turicata]"]
["JAW02453.1",10.85671508,10.90761069,"GO:0005975//carbohydrate metabolic process","GO:0033919//glucan 1,3-alpha-glucosidase activity;GO:0030246//carbohydrate binding;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds",null,"HsM7661898",961.4,{"v":1.1e-279,"d":"1.10E-279"},"KOG1066","Glucosidase II catalytic (alpha) subunit and related enzymes, glycosyl hydrolase family 31",null,"GMO","Carbohydrate transport and metabolism;Cell wall/membrane/envelope biogenesis;Posttranslational modification, protein turnover, chaperones","METABOLISM;CELLULAR PROCESSES AND SIGNALING;CELLULAR PROCESSES AND SIGNALING","K05546|1|0.0e+00|1292.7|isc:IscW_ISCW012920|mannosyl-oligosaccharide alpha-1,3-glucosidase [EC:3.2.1.207]","JAW02453.1","54590.2565804292;","51881.371897349;",1.05221305,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["ABR23354.1",10.7971276,10.84896738,"GO:0006412//translation","GO:0003735//structural constituent of ribosome;GO:0003723//RNA binding","GO:0022627//cytosolic small ribosomal subunit;GO:0015935//small ribosomal subunit","Hs15055539",404.1,{"v":1.7e-112,"d":"1.70E-112"},"KOG0877","40S ribosomal protein S2/30S ribosomal protein S5",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K02981|1|6.0e-116|421.0|dpx:DAPPUDRAFT_92887|small subunit ribosomal protein S2e","ABR23354.1","51480.9637434113;","48880.195814076;",1.053206987,"NA","NA","Non","40S ribosomal protein S2/30S [Ornithodoros parkeri]"]
["JAV99914.1",11.16778353,11.21977153,"GO:0035042//fertilization, exchange of chromosomal proteins;GO:0050848//regulation of calcium-mediated signaling;GO:0007274//neuromuscular synaptic transmission;GO:0006334//nucleosome assembly","GO:0042393//histone binding","GO:0005634//nucleus;GO:0005759//mitochondrial matrix",7302739,206.1,{"v":7.6e-53,"d":"7.60E-53"},"KOG4024","Complement component 1, Q subcomponent binding protein/mRNA splicing factor SF2, subunit P32",null,"V","Defense mechanisms","CELLULAR PROCESSES AND SIGNALING","K15414|1|8.2e-95|350.9|isc:IscW_ISCW020550|complement component 1 Q subcomponent-binding protein, mitochondrial","JAV99914.1","74590.7313734096;","70811.9838465644;",1.053363108,"NA","NA","Non","Glycoprotein gC1qBP, partial [Ornithodoros moubata]"]
["JAW04923.1",11.08599568,11.13798881,null,"GO:0005215//transporter activity;GO:0031409//pigment binding;GO:0008289//lipid binding",null,"Hs4502163",80.1,{"v":5e-15,"d":"5.00E-15"},"KOG4824","Apolipoprotein D/Lipocalin",null,"M","Cell wall/membrane/envelope biogenesis","CELLULAR PROCESSES AND SIGNALING","K03098|1|6.7e-31|138.3|dpx:DAPPUDRAFT_39582|apolipoprotein D and lipocalin family protein","JAW04923.1","68733.2816946081;","65250.9365007523;",1.053368509,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAV99331.1",11.03066618,11.08586332,"GO:0005975//carbohydrate metabolic process;GO:0005986//sucrose biosynthetic process;GO:0030388//fructose 1,6-bisphosphate metabolic process;GO:0006000//fructose metabolic process;GO:0006002//fructose 6-phosphate metabolic process;GO:0006094//gluconeogenesis","GO:0042132//fructose 1,6-bisphosphate 1-phosphatase activity","GO:0005829//cytosol",7298626,468,{"v":1.3e-131,"d":"1.30E-131"},"KOG1458","Fructose-1,6-bisphosphatase",null,"G","Carbohydrate transport and metabolism","METABOLISM","K03841|1|3.8e-158|561.6|isc:IscW_ISCW005292|fructose-1,6-bisphosphatase I [EC:3.1.3.11]","JAV99331.1","65242.3004073424;","61738.6960718183;",1.05674892,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW06713.1",10.95655632,11.01944192,"GO:0008152//metabolic process","GO:0003824//catalytic activity;GO:0008908//isochorismatase activity","GO:0005737//cytoplasm","Hs13376007",208.4,{"v":1.1e-53,"d":"1.10E-53"},"KOG4044","Mitochondrial associated endoribonuclease MAR1 (isochorismatase superfamily)",null,"R","General function prediction only","POORLY CHARACTERIZED","K04432|1|1.7e-12|77.0|tsp:Tsp_02206|mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]","JAW06713.1","61049.5995846214;","57328.6808873019;",1.064905012,"NA","NA","Non","Mitochondrial associated endoribonuclease MAR1-isochorismatase superfamily, partial [Ornithodoros moubata]"]
["JAR87444.1",10.57547214,10.64010766,"GO:0046331//lateral inhibition;GO:0005975//carbohydrate metabolic process;GO:0006099//tricarboxylic acid cycle;GO:0006107//oxaloacetate metabolic process;GO:0006734//NADH metabolic process;GO:0006108//malate metabolic process","GO:0030060//L-malate dehydrogenase activity","GO:0005829//cytosol;GO:0005777//peroxisome;GO:0005739//mitochondrion",7297683,370.2,{"v":3.5e-102,"d":"3.50E-102"},"KOG1496","Malate dehydrogenase",null,"C","Energy production and conversion","METABOLISM","K00025|1|1.6e-110|403.3|mde:101889109|malate dehydrogenase [EC:1.1.1.37]","JAR87444.1","41777.2689121136;","39162.3906894607;",1.066770138,"NA","NA","Non","malate dehydrogenase 1, partial [Alectorobius mimon]"]
["JAW04940.1",11.93362882,11.99976607,"GO:0006811//ion transport",null,"GO:0016021//integral component of membrane;GO:0005921//gap junction",{"$nulls":9},"K22037|1|4.5e-152|541.6|isc:IscW_ISCW002903|innexin","JAW04940.1","162716.722405604;","152303.241052608;",1.06837334,"NA","NA","Non","Innexin, partial [Ornithodoros moubata]"]
["JAV99290.1",11.51545762,11.58356143,null,null,"GO:0005576//extracellular region",7295977,125.9,{"v":1.1e-28,"d":"1.10E-28"},"KOG3017","Defense-related protein containing SCP domain",null,"S","Function unknown","POORLY CHARACTERIZED","K19867|1|1.9e-28|130.6|sko:100370249|LIM domain-binding protein 3!K21853|3|1.2e-19|101.3|dpte:113795450|dedicator of cytokinesis protein 9/10/11","JAV99290.1","107319.04794965;","100253.536388587;",1.070476432,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAV99364.1",13.12513753,13.19627696,"GO:0006457//protein folding;GO:1902175//regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:0019511//peptidyl-proline hydroxylation;GO:0045454//cell redox homeostasis;GO:0034976//response to endoplasmic reticulum stress","GO:0003756//protein disulfide isomerase activity;GO:0016757//transferase activity, transferring glycosyl groups","GO:0005783//endoplasmic reticulum",7294310,584.7,{"v":1.5e-166,"d":"1.50E-166"},"KOG0190","Protein disulfide isomerase (prolyl 4-hydroxylase beta subunit)",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K09580|1|3.8e-210|734.9|isc:IscW_ISCW010827|protein disulfide-isomerase A1 [EC:5.3.4.1]","JAV99364.1","538356.878749395;","501389.002855851;",1.073730927,"NA","NA","Non","Protein disulfide-isomerase, partial [Ornithodoros moubata]"]
["JAW02370.1",14.42995398,14.50554974,"GO:0008152//metabolic process","GO:0016162//cellulose 1,4-beta-cellobiosidase activity","GO:0016021//integral component of membrane","Hs20540124",94.7,{"v":8.9e-19,"d":"8.90E-19"},"KOG3510","FOG: Immunoglobulin C-2 Type/fibronectin type III domains",null,"T","Signal transduction mechanisms","CELLULAR PROCESSES AND SIGNALING","K16910|1|9.3e-88|329.3|isc:IscW_ISCW010023|receptor-type tyrosine-protein phosphatase Q [EC:3.1.3.48]!K06777|2|2.8e-28|131.7|pdam:113686858|receptor-type tyrosine-protein phosphatase delta [EC:3.1.3.48]","JAW02370.1","1993793.66084398;","1848627.41056585;",1.078526505,"NA","NA","Non","E3 ubiquitin-protein ligase TRIP12, partial [Ornithodoros moubata]"]
["JAV98697.1",10.43282694,10.5129513,"GO:0006457//protein folding;GO:0009306//protein secretion;GO:0006886//intracellular protein transport","GO:0003756//protein disulfide isomerase activity","GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0016021//integral component of membrane","At2g47470",67.4,{"v":3.8e-11,"d":"3.80E-11"},"KOG0191","Thioredoxin/protein disulfide isomerase",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K09586|1|3.0e-96|355.5|isc:IscW_ISCW018425|endoplasmic reticulum protein 29","JAV98697.1","36788.8944738761;","33956.2070139295;",1.083421787,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW04978.1",10.75950898,10.83968524,"GO:0006783//heme biosynthetic process;GO:0032780//negative regulation of ATPase activity","GO:0051117//ATPase binding;GO:0042030//ATPase inhibitor activity","GO:0005739//mitochondrion",7291563,74.3,{"v":1.5e-13,"d":"1.50E-13"},"KOG3093","5-formyltetrahydrofolate cyclo-ligase",null,"H","Coenzyme transport and metabolism","METABOLISM","K22255|1|7.1e-35|150.6|isc:IscW_ISCW001951|ATPase inhibitor, mitochondrial","JAW04978.1","51005.3212131026;","47075.5472344424;",1.083478031,"NA","NA","Non","Mitochondrial ATPase inhibitor, partial [Ornithodoros moubata]"]
["JAV99966.1",10.4406122,10.52113797,"GO:0045454//cell redox homeostasis","GO:0004601//peroxidase activity;GO:0051920//peroxiredoxin activity","GO:0016021//integral component of membrane;GO:0005623//cell","Hs5453549",377.5,{"v":1.8e-104,"d":"1.80E-104"},"KOG0852","Alkyl hydroperoxide reductase, thiol specific antioxidant and related enzymes",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K03386|1|3.7e-118|428.3|isc:IscW_ISCW013767|peroxiredoxin (alkyl hydroperoxide reductase subunit C) [EC:1.11.1.15]","JAV99966.1","37091.3091690724;","34221.5965109344;",1.083856773,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["XP_064487255.1",9.699910466,9.783246097,"GO:0035556//intracellular signal transduction;GO:0007268//chemical synaptic transmission;GO:0030036//actin cytoskeleton organization",null,"GO:0005622//intracellular","Hs18571892",65.1,{"v":2.4e-10,"d":"2.40E-10"},"KOG3605","Beta amyloid precursor-binding protein",null,"R","General function prediction only","POORLY CHARACTERIZED","K17254|1|2.8e-115|419.1|isc:IscW_ISCW005775|syntenin-1","XP_064487255.1","17734.1262180095;","16316.1462758638;",1.086906548,"NA","NA","Non","syntenin-1-like [Ornithodoros turicata] >XP_064487256.1 syntenin-1-like [Ornithodoros turicata]"]
["JAV99243.1",9.672395303,9.756620358,null,null,"GO:0016021//integral component of membrane","Hs15100151",154.5,{"v":2.3e-37,"d":"2.30E-37"},"KOG1553","Predicted alpha/beta hydrolase BAT5",null,"R","General function prediction only","POORLY CHARACTERIZED","K08869|1|3.8e-19|99.4|dpl:KGM_201356|aarF domain-containing kinase","JAV99243.1","17268.1727022071;","15873.3249437185;",1.087873698,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAV99309.1",11.79242952,11.87960064,"GO:0006457//protein folding","GO:0005509//calcium ion binding;GO:0051082//unfolded protein binding","GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum","Hs10716563",604,{"v":2.7e-172,"d":"2.70E-172"},"KOG0675","Calnexin",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K08054|1|5.0e-254|880.9|isc:IscW_ISCW003709|calnexin","JAV99309.1","144292.914518647;","132247.377636091;",1.09108337,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["XP_064455980.1",9.941271671,10.02966269,"GO:0007155//cell adhesion;GO:0007229//integrin-mediated signaling pathway",null,"GO:0016021//integral component of membrane",7290871,810.4,{"v":2.6e-234,"d":"2.60E-234"},"KOG1226","Integrin beta subunit (N-terminal portion of extracellular region)",null,"TW","Signal transduction mechanisms;Extracellular structures","CELLULAR PROCESSES AND SIGNALING;CELLULAR PROCESSES AND SIGNALING","K05719|1|9.5e-264|913.7|dpte:113792272|integrin beta 1","XP_064455980.1","22689.6167282256;","20770.1402913125;",1.092415189,"NA","NA","Non","integrin beta-PS-like [Ornithodoros turicata] >XP_064455981.1 integrin beta-PS-like [Ornithodoros turicata]"]
["JAT79259.1",10.47574936,10.56655636,"GO:0051216//cartilage development;GO:0033339//pectoral fin development;GO:0043010//camera-type eye development","GO:0004029//aldehyde dehydrogenase (NAD) activity;GO:0016491//oxidoreductase activity",null,"Hs4557343",556.2,{"v":5e-158,"d":"5.00E-158"},"KOG2453","Aldehyde dehydrogenase",null,"C","Energy production and conversion","METABOLISM","K14085|1|3.5e-207|724.9|isc:IscW_ISCW020189|aldehyde dehydrogenase family 7 member A1 [EC:1.2.1.31 1.2.1.8 1.2.1.3]","JAT79259.1","38814.7793251909;","35445.4212199801;",1.09505764,"NA","NA","Non","alpha aminoadipic semialdehyde dehydrogenase like, partial [Ornithodoros brasiliensis]"]
["JAW02509.1",11.4503986,11.54555906,"GO:0008152//metabolic process","GO:0016162//cellulose 1,4-beta-cellobiosidase activity;GO:0004725//protein tyrosine phosphatase activity","GO:0016021//integral component of membrane","Hs18860892",65.1,{"v":5.8e-10,"d":"5.80E-10"},"KOG4228","Protein tyrosine phosphatase",null,"T","Signal transduction mechanisms","CELLULAR PROCESSES AND SIGNALING","K01104|1|1.6e-18|99.0|pgc:109852334|protein-tyrosine phosphatase [EC:3.1.3.48]!K16353|2|1.7e-12|79.0|adf:107330776|protein sidekick!K05694|5|3.8e-12|77.8|lak:106156488|receptor-type tyrosine-protein phosphatase beta [EC:3.1.3.48]","JAW02509.1","103317.191352053;","93938.7828712808;",1.09983532,"NA","NA","Non","Cathepsin L, partial [Ornithodoros moubata]"]
["JAW02362.1",15.1086827,15.2069535,"GO:0006013//mannose metabolic process","GO:0046872//metal ion binding;GO:0004559//alpha-mannosidase activity;GO:0030246//carbohydrate binding",null,7297706,632.5,{"v":9.8e-181,"d":"9.80E-181"},"KOG1959","Glycosyl hydrolase, family 38 - alpha-mannosidase",null,"G","Carbohydrate transport and metabolism","METABOLISM","K12311|1|1.2e-194|684.1|zne:110837258|lysosomal alpha-mannosidase [EC:3.2.1.24]","JAW02362.1","4020647.41360941;","3644328.57287187;",1.103261502,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["XP_064473886.1",13.51926688,13.61893633,null,null,"GO:0016021//integral component of membrane",7293750,513.8,{"v":3.9e-145,"d":"3.90E-145"},"KOG3733","Mucolipidin and related proteins (TRML subfamily of transient receptor potential proteins)",null,"P","Inorganic ion transport and metabolism","METABOLISM","K04994|1|2.6e-245|852.0|isc:IscW_ISCW001660|mucolipin 3","XP_064473886.1","821540.348183182;","743606.205493734;",1.104805665,"NA","NA","Non","mucolipin-3-like [Ornithodoros turicata]"]
["JAV99845.1",11.14908493,11.25069944,null,null,"GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane",7296921,202.2,{"v":8.8e-52,"d":"8.80E-52"},"KOG1792","Reticulon",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K20721|1|9.3e-57|224.2|lgi:LOTGIDRAFT_230377|reticulon-1","JAV99845.1","76933.7112449302;","69500.2014756543;",1.106956665,"NA","NA","Non","Reticulon-like protein, partial [Ornithodoros moubata]"]
["JAR86909.1",8.999767967,9.110469157,"GO:0015986//ATP synthesis coupled proton transport","GO:0046933//proton-transporting ATP synthase activity, rotational mechanism","GO:0045261//proton-transporting ATP synthase complex, catalytic core F(1)","Hs4885079",293.5,{"v":3.2e-79,"d":"3.20E-79"},"KOG1531","F0F1-type ATP synthase, gamma subunit",null,"C","Energy production and conversion","METABOLISM","K02136|1|2.1e-105|386.0|isc:IscW_ISCW023477|F-type H+-transporting ATPase subunit gamma","JAR86909.1","9049.53954887318;","8101.20396000229;",1.117061068,"NA","NA","Non","g chain low resolution structures of bovine mitochondrial f1 atpase during controlled dehydration: hydration state, partial [Alectorobius mimon]"]
["JAW03116.1",10.34073164,10.45799692,null,"GO:0016787//hydrolase activity;GO:0003948//N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity",null,"Hs4557273",383.6,{"v":3.4e-106,"d":"3.40E-106"},"KOG1593","Asparaginase",null,"E","Amino acid transport and metabolism","METABOLISM","K01444|1|9.6e-136|487.3|isc:IscW_ISCW001950|N4-(beta-N-acetylglucosaminyl)-L-asparaginase [EC:3.5.1.26]","JAW03116.1","34821.7309225994;","30968.6795333596;",1.124417684,"NA","NA","Non","S- hydroxymethyl glutathione dehydrogenase, partial [Ornithodoros moubata]"]
["JAV99817.1",12.6794325,12.81001439,"GO:0006457//protein folding;GO:0030431//sleep;GO:0043277//apoptotic cell clearance;GO:2000427//positive regulation of apoptotic cell clearance;GO:0045454//cell redox homeostasis;GO:0034976//response to endoplasmic reticulum stress","GO:0033741//adenylyl-sulfate reductase (glutathione) activity;GO:0016853//isomerase activity;GO:0003756//protein disulfide isomerase activity","GO:0005623//cell;GO:0005783//endoplasmic reticulum",7298302,562,{"v":8.8e-160,"d":"8.80E-160"},"KOG0191","Thioredoxin/protein disulfide isomerase",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K09584|1|1.2e-196|689.9|isc:IscW_ISCW002080|protein disulfide-isomerase A6 [EC:5.3.4.1]","JAV99817.1","365863.059887446;","321075.796033636;",1.139491249,"NA","NA","Non","Protein disulfide isomerase-1, partial [Ornithodoros moubata]"]
["XP_064457395.1",11.67478122,11.80825773,"GO:0006635//fatty acid beta-oxidation","GO:0050660//flavin adenine dinucleotide binding;GO:0043958//acryloyl-CoA reductase activity;GO:0070991//medium-chain-acyl-CoA dehydrogenase activity;GO:0003995//acyl-CoA dehydrogenase activity;GO:0005524//ATP binding","GO:0005739//mitochondrion",7295201,616.3,{"v":3.8e-176,"d":"3.80E-176"},"KOG0140","Medium-chain acyl-CoA dehydrogenase",null,"I","Lipid transport and metabolism","METABOLISM","K00249|1|1.4e-178|629.8|tca:659081|acyl-CoA dehydrogenase [EC:1.3.8.7]","XP_064457395.1","134357.270552198;","117569.063684601;",1.142794425,"NA","NA","Non","medium-chain specific acyl-CoA dehydrogenase, mitochondrial-like isoform X2 [Ornithodoros turicata] >XP_064463939.1 medium-chain specific acyl-CoA dehydrogenase, mitochondrial-like isoform X2 [Ornithodoros turicata]"]
["XP_064458809.1",11.3140959,11.44965477,"GO:0007017//microtubule-based process;GO:0051301//cell division;GO:0030705//cytoskeleton-dependent intracellular transport","GO:0005200//structural constituent of cytoskeleton;GO:0003924//GTPase activity;GO:0005198//structural molecule activity;GO:0005525//GTP binding","GO:0005737//cytoplasm;GO:0031982//vesicle;GO:0005634//nucleus;GO:0045121//membrane raft;GO:0005881//cytoplasmic microtubule;GO:0005874//microtubule;GO:0015630//microtubule cytoskeleton","Hs14389309",879.8,{"v":2e-255,"d":"2.00E-255"},"KOG1376","Alpha tubulin",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K07374|1|8.5e-254|879.8|pon:100446260|tubulin alpha","XP_064458809.1","93868.9341759212;","81968.9583006522;",1.145176615,"NA","NA","Non","tubulin alpha-1C chain-like [Ornithodoros turicata]"]
["XP_064474635.1",9.425407578,9.563907322,{"$nulls":3},"Hs4506355",646.7,{"v":9.2e-185,"d":"9.20E-185"},"KOG1366","Alpha-macroglobulin",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K03910|1|1.9e-249|867.1|cfo:105250721|alpha-2-macroglobulin","XP_064474635.1","14241.3832917427;","12399.4522534943;",1.148549388,"NA","NA","Non","alpha-2-macroglobulin-like isoform X7 [Ornithodoros turicata]"]
["XP_064478578.1",9.790316329,9.929935358,"GO:0045776//negative regulation of blood pressure;GO:0097755//positive regulation of blood vessel diameter","GO:0004185//serine-type carboxypeptidase activity","GO:0070062//extracellular exosome","Hs11055992",435.3,{"v":1.3e-121,"d":"1.30E-121"},"KOG1283","Serine carboxypeptidases",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K09646|1|3.0e-126|456.1|els:105031322|serine carboxypeptidase 1 [EC:3.4.16.-]","XP_064478578.1","20536.0130493279;","17859.9548927269;",1.149835662,"NA","NA","Non","retinoid-inducible serine carboxypeptidase-like [Ornithodoros turicata]"]
["JAV99001.1",10.09819304,10.23902887,"GO:0006122//mitochondrial electron transport, ubiquinol to cytochrome c;GO:0009060//aerobic respiration;GO:0016485//protein processing","GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding;GO:0046872//metal ion binding","GO:0005750//mitochondrial respiratory chain complex III","Hs4758734",644,{"v":1.9e-184,"d":"1.90E-184"},"KOG0960","Mitochondrial processing peptidase, beta subunit, and related enzymes (insulinase superfamily)",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K17732|1|6.5e-244|847.0|isc:IscW_ISCW001592|mitochondrial-processing peptidase subunit beta [EC:3.4.24.64]","JAV99001.1","27973.9465186552;","24299.0623457725;",1.151235637,"NA","NA","Non","Processing peptidase beta subunit, partial [Ornithodoros moubata]"]
["JAV98879.1",13.82276622,13.9684595,null,null,"GO:0005765//lysosomal membrane;GO:0016021//integral component of membrane",7301577,55.8,{"v":1.4e-07,"d":"1.40E-07"},"KOG1520","Predicted alkaloid synthase/Surface mucin Hemomucin",null,"R","General function prediction only","POORLY CHARACTERIZED","K08458|1|8.3e-08|62.0|xma:111611445|adhesion G-protein coupled receptor F5","JAV98879.1","1165265.47795626;","1007282.04460373;",1.156841308,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAV99377.1",9.983097834,10.13044097,{"$nulls":3},7299991,404.8,{"v":1.2e-112,"d":"1.20E-112"},"KOG1003","Actin filament-coating protein tropomyosin",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K10373|1|1.8e-132|476.1|dpte:113794926|tropomyosin 1","JAV99377.1","25095.428390787;","21657.2994670147;",1.158751507,"NA","NA","Non","CRE-LEV-11 protein, partial [Ornithodoros moubata]"]
["JAV99072.1",12.78396611,12.93195288,"GO:0005975//carbohydrate metabolic process","GO:0030246//carbohydrate binding;GO:0032450//maltose alpha-glucosidase activity;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0004558//alpha-1,4-glucosidase activity","GO:0016021//integral component of membrane","Hs4503849",754.2,{"v":2.5e-217,"d":"2.50E-217"},"KOG1065","Maltase glucoamylase and related hydrolases, glycosyl hydrolase family 31",null,"G","Carbohydrate transport and metabolism","METABOLISM","K12316|1|3.8e-277|958.4|isc:IscW_ISCW011416|lysosomal alpha-glucosidase [EC:3.2.1.20]","JAV99072.1","413309.870318239;","356456.007262924;",1.159497559,"NA","NA","Non","Glycosyl hydralase sucrase-isomaltase, partial [Ornithodoros moubata]"]
["XP_064460796.1",10.34024182,10.49018819,"GO:1990830//cellular response to leukemia inhibitory factor;GO:0008295//spermidine biosynthetic process","GO:0042802//identical protein binding;GO:0004766//spermidine synthase activity;GO:0042803//protein homodimerization activity",null,"Hs4507209",365.9,{"v":6.2e-101,"d":"6.20E-101"},"KOG1562","Spermidine synthase",null,"E","Amino acid transport and metabolism","METABOLISM","K00797|1|5.5e-105|384.8|dpx:DAPPUDRAFT_304917|spermidine synthase [EC:2.5.1.16]","XP_064460796.1","35960.9241433387;","30953.514419245;",1.161771929,"NA","NA","Non","spermidine synthase-like [Ornithodoros turicata] >XP_064460798.1 spermidine synthase-like [Ornithodoros turicata]"]
["JAW00727.1",10.43746091,10.58877368,"GO:0000028//ribosomal small subunit assembly","GO:0003735//structural constituent of ribosome;GO:0003723//RNA binding","GO:0022627//cytosolic small ribosomal subunit;GO:0005840//ribosome","Hs4506679",174.1,{"v":1.5e-43,"d":"1.50E-43"},"KOG3344","40s ribosomal protein s10",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K02947|1|4.1e-57|224.6|isc:IscW_ISCW023883|small subunit ribosomal protein S10e","JAW00727.1","39686.7906307568;","34113.924200721;",1.163360462,"NA","NA","Non","Glycogen synthase, partial [Ornithodoros moubata]"]
["JAV98829.1",12.66064768,12.81225888,null,null,"GO:0016021//integral component of membrane","Hs21361755",381.3,{"v":1.4e-105,"d":"1.40E-105"},"KOG2621","Prohibitins and stomatins of the PID superfamily",null,"C","Energy production and conversion","METABOLISM","K17286|1|5.0e-130|468.0|isc:IscW_ISCW002156|erythrocyte band 7 integral membrane protein","JAV98829.1","366685.15808798;","315100.741072497;",1.163707698,"NA","NA","Non","MEC-2 isoform b, partial [Ornithodoros moubata]"]
["JAV98691.1",9.846611105,10.00142045,"GO:0030041//actin filament polymerization;GO:0034314//Arp2/3 complex-mediated actin nucleation","GO:0003779//actin binding","GO:0005737//cytoplasm;GO:0005885//Arp2/3 protein complex","Hs5031595",295,{"v":7.8e-80,"d":"7.80E-80"},"KOG1876","Actin-related protein Arp2/3 complex, subunit ARPC4",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K05755|1|2.9e-82|308.5|fcd:110854095|actin related protein 2/3 complex, subunit 4","JAV98691.1","22057.7755398156;","18894.2156753404;",1.167435363,"NA","NA","Non","ARP2-3 complex 20 kDa subunit P20-ARC, partial [Ornithodoros moubata]"]
["JAV99335.1",12.61460425,12.77198388,"GO:0008637//apoptotic mitochondrial changes;GO:0045041//protein import into mitochondrial intermembrane space;GO:0006458//'de novo' protein folding;GO:0042026//protein refolding;GO:0061077//chaperone-mediated protein folding","GO:0044183//protein binding involved in protein folding;GO:0051082//unfolded protein binding;GO:0005524//ATP binding","GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005739//mitochondrion",7292599,871.3,{"v":8.8e-253,"d":"8.80E-253"},"KOG0356","Mitochondrial chaperonin, Cpn60/Hsp60p",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K04077|1|9.0e-277|956.4|isc:IscW_ISCW017824|chaperonin GroEL","JAV99335.1","352210.357628586;","300921.359375375;",1.170439873,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW01330.1",9.75611315,9.914998205,null,"GO:0005215//transporter activity","GO:0005737//cytoplasm;GO:0016021//integral component of membrane","Hs4504611",222.2,{"v":2.4e-57,"d":"2.40E-57"},"KOG4504","Cation-independent mannose-6-phosphate receptor CI-MPR",null,"TU","Signal transduction mechanisms;Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING;CELLULAR PROCESSES AND SIGNALING","K06564|1|2.2e-66|257.7|crg:105339958|insulin-like growth factor 2 receptor","JAW01330.1","20231.5431086303;","17259.41637379;",1.1722032,"NA","NA","Non","39S ribosomal protein L51, partial [Ornithodoros moubata]"]
["JAV99822.1",10.32234713,10.48453869,"GO:0006511//ubiquitin-dependent protein catabolic process","GO:0004298//threonine-type endopeptidase activity","GO:0005737//cytoplasm;GO:0019773//proteasome core complex, alpha-subunit complex;GO:0005634//nucleus","Hs4506185",423.7,{"v":2.3e-118,"d":"2.30E-118"},"KOG0178","20S proteasome, regulatory subunit alpha type PSMA4/PRE9",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K02728|1|5.4e-123|444.5|tut:107360103|20S proteasome subunit alpha 3 [EC:3.4.25.1]","JAV99822.1","35758.3356582073;","30404.5372882976;",1.176085507,"NA","NA","Non","Proteasome subunit alpha type, partial [Ornithodoros moubata]"]
["XP_064478248.1",11.95773111,12.1216547,"GO:0006004//fucose metabolic process","GO:0004560//alpha-L-fucosidase activity",null,"Hs4503803",563.9,{"v":2.5e-160,"d":"2.50E-160"},"KOG3340","Alpha-L-fucosidase",null,"G","Carbohydrate transport and metabolism","METABOLISM","K01206|1|2.3e-185|652.5|isc:IscW_ISCW012070|alpha-L-fucosidase [EC:3.2.1.51]","XP_064478248.1","183809.413379293;","156018.694010677;",1.178124292,"NA","NA","Non","alpha-L-fucosidase-like [Ornithodoros turicata]"]
["XP_064458044.1",12.92384828,13.09107399,"GO:0006013//mannose metabolic process","GO:0046872//metal ion binding;GO:0004559//alpha-mannosidase activity;GO:0030246//carbohydrate binding",null,7297706,872.5,{"v":7e-253,"d":"7.00E-253"},"KOG1959","Glycosyl hydrolase, family 38 - alpha-mannosidase",null,"G","Carbohydrate transport and metabolism","METABOLISM","K12311|1|5.8e-271|937.9|zne:110837258|lysosomal alpha-mannosidase [EC:3.2.1.24]","XP_064458044.1","484597.528564505;","409973.694973235;",1.182021028,"NA","NA","Non","lysosomal alpha-mannosidase-like isoform X2 [Ornithodoros turicata]"]
["JAV99954.1",13.27186336,13.44048847,"GO:0006457//protein folding","GO:0005509//calcium ion binding;GO:0051082//unfolded protein binding","GO:0005783//endoplasmic reticulum","Hs4757900",656.8,{"v":2.5e-188,"d":"2.50E-188"},"KOG0674","Calreticulin",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K08057|1|1.3e-203|713.0|isc:IscW_ISCW008184|calreticulin","JAV99954.1","687274.095646043;","580626.72410447;",1.183676305,"NA","NA","Non","Calreticulin, partial [Ornithodoros moubata]"]
["JAV99013.1",10.05508787,10.22750137,{"$nulls":3},"Hs21361399",959.1,{"v":3.4e-279,"d":"3.40E-279"},"KOG0211","Protein phosphatase 2A regulatory subunit A and related proteins",null,"T","Signal transduction mechanisms","CELLULAR PROCESSES AND SIGNALING","K03456|1|1.9e-290|1001.9|soc:105200773|serine/threonine-protein phosphatase 2A regulatory subunit A","JAV99013.1","27653.3282204471;","23273.9006316277;",1.188169042,"NA","NA","Non","Protein phosphatase 2A regulatory subunit A, partial [Ornithodoros moubata]"]
["JAW02498.1",9.567427479,9.746246059,"GO:0008152//metabolic process","GO:0003824//catalytic activity",null,"Hs4507521",405.2,{"v":1.1e-112,"d":"1.10E-112"},"KOG0523","Transketolase",null,"G","Carbohydrate transport and metabolism","METABOLISM","K00615|1|2.2e-124|449.5|zne:110831149|transketolase [EC:2.2.1.1]","JAW02498.1","17089.9535565914;","14291.603541569;",1.195803781,"NA","NA","Non","Methionine aminopeptidase 1, partial [Ornithodoros moubata]"]
["JAW02848.1",13.14163609,13.32399689,"GO:0046902//regulation of mitochondrial membrane permeability;GO:0055085//transmembrane transport","GO:0005215//transporter activity;GO:0005471//ATP:ADP antiporter activity","GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane",7292557,511.9,{"v":7.2e-145,"d":"7.20E-145"},"KOG0749","Mitochondrial ADP/ATP carrier proteins",null,"C","Energy production and conversion","METABOLISM","K05863|1|5.1e-154|547.7|zne:110836319|solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31","JAW02848.1","611699.782496995;","509729.815618864;",1.200047091,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW03668.1",11.74887076,11.94061659,"GO:0007155//cell adhesion;GO:0007229//integrin-mediated signaling pathway",null,"GO:0016021//integral component of membrane",7290871,765.4,{"v":7.8e-221,"d":"7.80E-221"},"KOG1226","Integrin beta subunit (N-terminal portion of extracellular region)",null,"TW","Signal transduction mechanisms;Extracellular structures","CELLULAR PROCESSES AND SIGNALING;CELLULAR PROCESSES AND SIGNALING","K05719|1|3.5e-240|835.1|dpte:113792272|integrin beta 1","JAW03668.1","153371.227504538;","126610.504719706;",1.211362579,"NA","NA","Non","Integrin beta, partial [Ornithodoros moubata]"]
["XP_064489081.1",9.833604499,10.02590299,"GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway","GO:0031683//G-protein beta/gamma-subunit complex binding;GO:0003924//GTPase activity;GO:0004871//signal transducer activity;GO:0005525//GTP binding",null,"HsM20149537",590.1,{"v":2.5e-168,"d":"2.50E-168"},"KOG0082","G-protein alpha subunit (small G protein superfamily)",null,"DT","Cell cycle control, cell division, chromosome partitioning;Signal transduction mechanisms","CELLULAR PROCESSES AND SIGNALING;CELLULAR PROCESSES AND SIGNALING","K04630|1|2.7e-178|628.6|zne:110827220|guanine nucleotide-binding protein G(i) subunit alpha","XP_064489081.1","22604.4708431704;","18650.0573380959;",1.212032244,"NA","NA","Non","guanine nucleotide-binding protein G(i) subunit alpha-like [Ornithodoros turicata] >XP_064489083.1 guanine nucleotide-binding protein G(i) subunit alpha-like [Ornithodoros turicata]"]
["XP_064474870.1",11.14188018,11.34259335,"GO:0006457//protein folding;GO:0045454//cell redox homeostasis;GO:0034976//response to endoplasmic reticulum stress","GO:0003756//protein disulfide isomerase activity;GO:0016757//transferase activity, transferring glycosyl groups","GO:0005783//endoplasmic reticulum",7303555,572.4,{"v":7.3e-163,"d":"7.30E-163"},"KOG0190","Protein disulfide isomerase (prolyl 4-hydroxylase beta subunit)",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K08056|1|3.7e-210|734.9|isc:IscW_ISCW016161|protein disulfide-isomerase A3 [EC:5.3.4.1]","XP_064474870.1","84338.4671797359;","69001.269221285;",1.222274143,"NA","NA","Non","protein disulfide-isomerase A3-like [Ornithodoros turicata]"]
["AAN10129.1",12.57612709,12.78958401,{"$nulls":3},"Hs4506355",647.9,{"v":4.2e-185,"d":"4.20E-185"},"KOG1366","Alpha-macroglobulin",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K03910|1|4.4e-246|855.9|hst:105187657|alpha-2-macroglobulin","AAN10129.1","358464.176082644;","289562.688903564;",1.237950157,"NA","NA","Non","alpha-2-macroglobulin precursor splice variant 1 [Ornithodoros moubata]"]
["JAW01857.1",9.270177996,9.487056778,null,null,"GO:0016021//integral component of membrane",7301116,371.3,{"v":1.4e-102,"d":"1.40E-102"},"KOG3839","Lectin VIP36, involved in the transport of glycoproteins carrying high mannose-type glycans",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K10082|1|1.7e-146|522.7|isc:IscW_ISCW012623|lectin, mannose-binding 2","JAW01857.1","13187.923169059;","10616.6414381857;",1.242193517,"NA","NA","Non","Ikappab kinase complex-associated protein, partial [Ornithodoros moubata]"]
["JAV99557.1",10.43438885,10.65455062,null,"GO:0050038//L-xylulose reductase (NADP+) activity;GO:0033814//propanoyl-CoA C-acyltransferase activity",null,"CE02490_1",394.4,{"v":2.3e-109,"d":"2.30E-109"},"KOG0725","Reductases with broad range of substrate specificities",null,"R","General function prediction only","POORLY CHARACTERIZED","K11147|1|3.2e-18|97.1|lcm:102359768|dehydrogenase/reductase SDR family member 4 [EC:1.1.-.-]!K11163|3|1.6e-17|94.7|pvt:110083614|dehydrogenase/reductase SDR family member 1 [EC:1.1.-.-]","JAV99557.1","42385.034367508;","34009.2849133305;",1.246278317,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW03330.1",13.58623189,13.80769389,null,null,"GO:0016021//integral component of membrane",{"$nulls":10},"JAW03330.1","992213.80674395;","795106.933026807;",1.24789983,"NA","NA","Non","hypothetical protein, partial [Ornithodoros moubata]"]
["JAW06909.1",10.34775845,10.57371675,null,"GO:0033897//ribonuclease T2 activity;GO:0003723//RNA binding",null,7295178,128.3,{"v":1.8e-29,"d":"1.80E-29"},"KOG1642","Ribonuclease, T2 family",null,"A","RNA processing and modification","INFORMATION STORAGE AND PROCESSING","K01166|1|2.2e-38|163.3|isc:IscW_ISCW014208|ribonuclease T2 [EC:3.1.27.1]","JAW06909.1","39093.7055003719;","31187.0571766094;",1.253523386,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW04653.1",9.406168616,9.632926307,null,"GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0008603//cAMP-dependent protein kinase regulator activity;GO:0016301//kinase activity;GO:0030552//cAMP binding","GO:0005952//cAMP-dependent protein kinase complex",7303815,113.2,{"v":3.8e-25,"d":"3.80E-25"},"KOG1113","cAMP-dependent protein kinase types I and II, regulatory subunit",null,"T","Signal transduction mechanisms","CELLULAR PROCESSES AND SIGNALING","K04739|1|2.0e-29|132.9|isc:IscW_ISCW013063|cAMP-dependent protein kinase regulator","JAW04653.1","15259.0234214032;","12163.1797755894;",1.254525848,"NA","NA","Non","cAMP-dependent protein kinase type II regulatory subunit, partial [Ornithodoros moubata]"]
["JAV98930.1",11.48337901,11.71879784,"GO:0006099//tricarboxylic acid cycle","GO:0004108//citrate (Si)-synthase activity",null,"Hs4758076",674.9,{"v":1e-193,"d":"1.00E-193"},"KOG2617","Citrate synthase",null,"C","Energy production and conversion","METABOLISM","K01647|1|1.3e-209|733.0|dpte:113795567|citrate synthase [EC:2.3.3.1]","JAV98930.1","122859.640004736;","97088.5770728766;",1.265438672,"NA","NA","Non","Citrate synthase, partial [Ornithodoros moubata]"]
["JAT79016.1",12.89163411,13.13921479,"GO:0015986//ATP synthesis coupled proton transport","GO:0005524//ATP binding;GO:0046933//proton-transporting ATP synthase activity, rotational mechanism","GO:0045261//proton-transporting ATP synthase complex, catalytic core F(1)","Hs4757810",842.4,{"v":4e-244,"d":"4.00E-244"},"KOG1353","F0F1-type ATP synthase, alpha subunit",null,"C","Energy production and conversion","METABOLISM","K02132|1|4.5e-259|897.5|isc:IscW_ISCW011988|F-type H+-transporting ATPase subunit alpha","JAT79016.1","508497.097680016;","396977.19217705;",1.280922702,"NA","NA","Non","atp synthase subunit mitochondrial like, partial [Ornithodoros brasiliensis]"]
["JAW01127.1",10.12910275,10.37853022,"GO:0055114//oxidation-reduction process","GO:0009055//electron transfer activity","GO:0005829//cytosol",7301831,346.3,{"v":4.1e-95,"d":"4.10E-95"},"KOG3180","Electron transfer flavoprotein, beta subunit",null,"C","Energy production and conversion","METABOLISM","K03521|1|3.5e-113|411.8|isc:IscW_ISCW012010|electron transfer flavoprotein beta subunit","JAW01127.1","32161.656030873;","25061.8675857353;",1.283290478,"NA","NA","Non","Malate dehydrogenase, partial [Ornithodoros moubata]"]
["JAV99444.1",12.91448297,13.17249063,"GO:0032355//response to estradiol;GO:0071398//cellular response to fatty acid;GO:0043066//negative regulation of apoptotic process;GO:0035094//response to nicotine;GO:0033574//response to testosterone;GO:0032870//cellular response to hormone stimulus;GO:0001889//liver development;GO:0032570//response to progesterone;GO:0032496//response to lipopolysaccharide;GO:0055093//response to hyperoxia;GO:0006068//ethanol catabolic process","GO:0004029//aldehyde dehydrogenase (NAD) activity;GO:0070404//NADH binding;GO:0042802//identical protein binding;GO:0001758//retinal dehydrogenase activity;GO:0016491//oxidoreductase activity","GO:0070062//extracellular exosome;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix","Hs11436533",724.9,{"v":9.4e-209,"d":"9.40E-209"},"KOG2450","Aldehyde dehydrogenase",null,"C","Energy production and conversion","METABOLISM","K00128|1|8.7e-234|813.5|isc:IscW_ISCW014613|aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]","JAV99444.1","525702.438591182;","406152.086216364;",1.294348734,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW06600.1",12.39067926,12.65287661,null,null,"GO:0016020//membrane",7298546,427.6,{"v":1.6e-119,"d":"1.60E-119"},"KOG3083","Prohibitin",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K17080|1|1.0e-124|450.3|tnl:113501490|prohibitin 1","JAW06600.1","312661.562052918;","240549.04008528;",1.299783038,"NA","NA","Non","Prohibitin, partial [Ornithodoros moubata]"]
["XP_064481846.1",11.04498192,11.30957374,"GO:0060059//embryonic retina morphogenesis in camera-type eye;GO:0015991//ATP hydrolysis coupled proton transport;GO:0060036//notochord cell vacuolation;GO:0001878//response to yeast;GO:0007042//lysosomal lumen acidification;GO:0060041//retina development in camera-type eye","GO:0046961//proton-transporting ATPase activity, rotational mechanism;GO:0015078//hydrogen ion transmembrane transporter activity","GO:0016021//integral component of membrane;GO:0005774//vacuolar membrane;GO:0033179//proton-transporting V-type ATPase, V0 domain;GO:0000220//vacuolar proton-transporting V-type ATPase, V0 domain",7302268,244.6,{"v":1.1e-64,"d":"1.10E-64"},"KOG0232","Vacuolar H+-ATPase V0 sector, subunits c/c'",null,"C","Energy production and conversion","METABOLISM","K02155|1|1.9e-72|275.8|isc:IscW_ISCW018346|V-type H+-transporting ATPase 16kDa proteolipid subunit","XP_064481846.1","81599.1185329581;","62628.8882703434;",1.302899042,"NA","NA","Non","V-type proton ATPase 16 kDa proteolipid subunit c-like [Ornithodoros turicata]"]
["JAW02916.1",13.85020873,14.11857058,null,"GO:0019904//protein domain specific binding",null,"CE03389",412.5,{"v":4.9e-115,"d":"4.90E-115"},"KOG0841","Multifunctional chaperone (14-3-3 family)",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K16197|1|3.2e-130|468.4|pcf:106788536|14-3-3 protein beta/theta/zeta","JAW02916.1","1353995.73627875;","1035307.17548745;",1.307820296,"NA","NA","Non","PH and SEC7 domain-containing protein 3, partial [Ornithodoros moubata]"]
["JAV99280.1",11.82047138,12.09354954,"GO:0006099//tricarboxylic acid cycle;GO:0006102//isocitrate metabolic process","GO:0004450//isocitrate dehydrogenase (NADP+) activity;GO:0000287//magnesium ion binding;GO:0051287//NAD binding",null,"Hs4504575",630.6,{"v":2.1e-180,"d":"2.10E-180"},"KOG1526","NADP-dependent isocitrate dehydrogenase",null,"C","Energy production and conversion","METABOLISM","K00031|1|1.2e-228|796.2|isc:IscW_ISCW001977|isocitrate dehydrogenase [EC:1.1.1.42]","JAV99280.1","178715.340600987;","136008.325936504;",1.314002943,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["XP_064455161.1",11.52781515,11.80110826,"GO:0007017//microtubule-based process","GO:0003924//GTPase activity;GO:0005200//structural constituent of cytoskeleton;GO:0005525//GTP binding","GO:0005737//cytoplasm;GO:0005874//microtubule","Hs17986283",586.6,{"v":2.3e-167,"d":"2.30E-167"},"KOG1376","Alpha tubulin",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K07374|1|1.2e-166|589.7|pret:103460255|tubulin alpha","XP_064455161.1","133400.113361577;","101500.108768804;",1.314285423,"NA","NA","Non","tubulin alpha chain-like [Ornithodoros turicata]"]
["JAW02761.1",8.558068323,8.83407862,"GO:0005975//carbohydrate metabolic process;GO:0006030//chitin metabolic process;GO:0006032//chitin catabolic process","GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0008061//chitin binding;GO:0004568//chitinase activity","GO:0005737//cytoplasm;GO:0016021//integral component of membrane;GO:0005576//extracellular region",7299808,259.2,{"v":1.1e-68,"d":"1.10E-68"},"KOG2806","Chitinase",null,"G","Carbohydrate transport and metabolism","METABOLISM","K01183|1|9.9e-84|314.7|isc:IscW_ISCW016316|chitinase [EC:3.2.1.14]","JAW02761.1","6864.2263679549;","5208.61009378957;",1.317861434,"NA","NA","Non","Adenosine monophosphate deaminase, partial [Ornithodoros moubata]"]
["XP_064456269.1",10.31774781,10.59438048,null,"GO:0003995//acyl-CoA dehydrogenase activity;GO:0050660//flavin adenine dinucleotide binding",null,7302495,654.1,{"v":2.5e-187,"d":"2.50E-187"},"KOG0137","Very-long-chain acyl-CoA dehydrogenase",null,"I","Lipid transport and metabolism","METABOLISM","K09479|1|4.9e-207|724.9|dnx:107164135|very long chain acyl-CoA dehydrogenase [EC:1.3.8.9]","XP_064456269.1","39909.9315709017;","30265.0182384436;",1.318681894,"NA","NA","Non","very long-chain specific acyl-CoA dehydrogenase, mitochondrial-like [Ornithodoros turicata]"]
["JAW05836.1",9.475976566,9.754629054,"GO:0051603//proteolysis involved in cellular protein catabolic process","GO:0004298//threonine-type endopeptidase activity","GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005839//proteasome core complex","Hs4506195",259.2,{"v":5.6e-69,"d":"5.60E-69"},"KOG0177","20S proteasome, regulatory subunit beta type PSMB2/PRE1",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K02734|1|1.6e-79|299.7|zne:110832371|20S proteasome subunit beta 4 [EC:3.4.25.1]","JAW05836.1","17233.8207416848;","13042.6047430932;",1.32134808,"NA","NA","Non","Proteasome subunit beta type, partial [Ornithodoros moubata]"]
["XP_064488904.1",10.72182564,11.00104647,"GO:0042744//hydrogen peroxide catabolic process;GO:0006979//response to oxidative stress","GO:0046872//metal ion binding;GO:0020037//heme binding;GO:0004096//catalase activity",null,"Hs4557014",708.8,{"v":6.7e-204,"d":"6.70E-204"},"KOG0047","Catalase",null,"P","Inorganic ion transport and metabolism","METABOLISM","K03781|1|1.5e-214|749.6|phu:Phum_PHUM336860|catalase [EC:1.11.1.6]","XP_064488904.1","59936.8309488992;","45334.59213409;",1.322099265,"NA","NA","Non","catalase-like isoform X2 [Ornithodoros turicata]"]
["JAR87176.1",9.334647772,9.614810889,"GO:0006627//protein processing involved in protein targeting to mitochondrion","GO:0004222//metalloendopeptidase activity;GO:0003824//catalytic activity;GO:0008270//zinc ion binding;GO:0046872//metal ion binding","GO:0005751//mitochondrial respiratory chain complex IV;GO:0070062//extracellular exosome;GO:0005750//mitochondrial respiratory chain complex III;GO:0043209//myelin sheath;GO:0005743//mitochondrial inner membrane;GO:0005654//nucleoplasm","Hs4507843",159.5,{"v":5.4e-39,"d":"5.40E-39"},"KOG2583","Ubiquinol cytochrome c reductase, subunit QCR2",null,"C","Energy production and conversion","METABOLISM","K00415|1|1.7e-40|169.9|srx:107717493|ubiquinol-cytochrome c reductase core subunit 2","JAR87176.1","14985.0885567254;","11323.6390582069;",1.323345656,"NA","NA","Non","cytochrome b c1 complex subunit mitochondrial like, partial [Alectorobius mimon]"]
["JAW04167.1",7.806100052,8.088284237,null,"GO:0016491//oxidoreductase activity",null,7296705,287.7,{"v":1.9e-77,"d":"1.90E-77"},"KOG0725","Reductases with broad range of substrate specificities",null,"R","General function prediction only","POORLY CHARACTERIZED","K10956|1|1.1e-54|217.6|egl:EGR_00201|protein transport protein SEC61 subunit alpha!K10402|2|1.3e-41|174.1|dpte:113790734|kinesin family member 20!K03331|4|2.1e-34|150.2|epa:110238560|L-xylulose reductase [EC:1.1.1.10]","JAW04167.1","3256.09608711322;","2455.53527743087;",1.326022932,"NA","NA","Non","3-oxoacyl-[acyl-carrier-protein] synthase, partial [Ornithodoros moubata]"]
["JAV99824.1",13.11840023,13.40770292,"GO:0008152//metabolic process;GO:0006635//fatty acid beta-oxidation","GO:0003824//catalytic activity;GO:0004300//enoyl-CoA hydratase activity","GO:0005739//mitochondrion",7303265,337.4,{"v":2.3e-92,"d":"2.30E-92"},"KOG1680","Enoyl-CoA hydratase",null,"I","Lipid transport and metabolism","METABOLISM","K07511|1|5.2e-119|431.4|isc:IscW_ISCW012475|enoyl-CoA hydratase [EC:4.2.1.17]","JAV99824.1","665106.804881656;","498022.347522417;",1.335495903,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAV99423.1",13.43103483,13.72062333,{"$nulls":12},"K04506|1|2.3e-12|76.3|fcd:110844856|E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]","JAV99423.1","909475.494990252;","680807.467945307;",1.335877671,"NA","NA","Non","Methyltransferase-like protein, partial [Ornithodoros moubata]"]
["JAW02042.1",10.3403398,10.63163842,"GO:0048899//anterior lateral line development;GO:0042552//myelination;GO:0036269//swimming behavior;GO:0010842//retina layer formation;GO:0046464//acylglycerol catabolic process;GO:0043010//camera-type eye development;GO:0048919//posterior lateral line neuromast development","GO:0016787//hydrolase activity;GO:0047372//acylglycerol lipase activity","GO:0016021//integral component of membrane","Hs20559602",199.9,{"v":6.8e-51,"d":"6.80E-51"},"KOG1552","Predicted alpha/beta hydrolase",null,"R","General function prediction only","POORLY CHARACTERIZED","K13704|1|3.1e-83|312.8|isc:IscW_ISCW014936|abhydrolase domain-containing protein 12 [EC:3.1.1.23]","JAW02042.1","41424.9411118849;","30956.5474420679;",1.338164121,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAV99175.1",12.10034583,12.39376183,"GO:0033539//fatty acid beta-oxidation using acyl-CoA dehydrogenase","GO:0016491//oxidoreductase activity;GO:0050660//flavin adenine dinucleotide binding;GO:0009055//electron transfer activity",null,7303574,428.3,{"v":1.2e-119,"d":"1.20E-119"},"KOG3954","Electron transfer flavoprotein, alpha subunit",null,"C","Energy production and conversion","METABOLISM","K03522|1|2.2e-137|492.7|isc:IscW_ISCW014575|electron transfer flavoprotein alpha subunit","JAV99175.1","241291.693986599;","179934.078969351;",1.341000523,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW02346.1",10.66302873,10.95877221,"GO:0034113//heterotypic cell-cell adhesion;GO:0034446//substrate adhesion-dependent cell spreading;GO:0007160//cell-matrix adhesion;GO:0050900//leukocyte migration;GO:0050901//leukocyte tethering or rolling;GO:0050904//diapedesis;GO:0003366//cell-matrix adhesion involved in ameboidal cell migration;GO:0030183//B cell differentiation;GO:2000406//positive regulation of T cell migration;GO:0007159//leukocyte cell-cell adhesion;GO:0007155//cell adhesion;GO:0035987//endodermal cell differentiation;GO:0050776//regulation of immune response;GO:0071345//cellular response to cytokine stimulus;GO:0007229//integrin-mediated signaling pathway;GO:1990771//clathrin-dependent extracellular exosome endocytosis;GO:0090074//negative regulation of protein homodimerization activity;GO:0030198//extracellular matrix organization;GO:1903238//positive regulation of leukocyte tethering or rolling;GO:0098657//import into cell;GO:0043113//receptor clustering","GO:1990405//protein antigen binding;GO:0046872//metal ion binding;GO:0015026//coreceptor activity;GO:0001968//fibronectin binding;GO:0019960//C-X3-C chemokine binding;GO:0050839//cell adhesion molecule binding;GO:0004621//glycosylphosphatidylinositol phospholipase D activity","GO:0005925//focal adhesion;GO:0070062//extracellular exosome;GO:0016020//membrane;GO:0009986//cell surface;GO:0008305//integrin complex;GO:0005886//plasma membrane;GO:0034669//integrin alpha4-beta7 complex","Hs4504749",326.2,{"v":1.7e-88,"d":"1.70E-88"},"KOG3637","Vitronectin receptor, alpha subunit",null,"W","Extracellular structures","CELLULAR PROCESSES AND SIGNALING","K06483|1|3.2e-87|327.4|nle:100602993|integrin alpha 4","JAW02346.1","57455.856022289;","42745.9071547332;",1.344125317,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAV99221.1",9.528125268,9.824628852,null,"GO:0005509//calcium ion binding","GO:0016021//integral component of membrane",7296269,351.7,{"v":1.7e-96,"d":"1.70E-96"},"KOG4260","Uncharacterized conserved protein",null,"S","Function unknown","POORLY CHARACTERIZED","K17675|1|5.7e-52|209.1|tsp:Tsp_02850|ATP-dependent RNA helicase SUPV3L1/SUV3 [EC:3.6.4.13]!K19020|2|8.6e-16|89.0|ola:101164383|stabilin-1","JAV99221.1","18483.4100064958;","13740.8065969279;",1.345147381,"NA","NA","Non","GI11694, partial [Ornithodoros moubata]"]
["JAW04097.1",12.15687194,12.4559499,"GO:0007166//cell surface receptor signaling pathway",null,"GO:0016021//integral component of membrane;GO:0005887//integral component of plasma membrane",7304278,59.7,{"v":5.6e-09,"d":"5.60E-09"},"KOG3882","Tetraspanin family integral membrane protein",null,"R","General function prediction only","POORLY CHARACTERIZED","K06460|1|7.2e-44|181.0|isc:IscW_ISCW010731|CD9 antigen!K06497|4|1.0e-13|80.9|shx:MS3_01370|CD63 antigen","JAW04097.1","256773.564741647;","190398.007708403;",1.348614767,"NA","NA","Non","Tetraspanin, partial [Ornithodoros moubata]"]
["JAW02477.1",11.71735695,12.01973851,"GO:0006635//fatty acid beta-oxidation;GO:0008152//metabolic process","GO:0003988//acetyl-CoA C-acyltransferase activity;GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups","GO:0016021//integral component of membrane;GO:0005739//mitochondrion","Hs4504327",601.7,{"v":1.1e-171,"d":"1.10E-171"},"KOG1392","Acetyl-CoA acetyltransferase",null,"I","Lipid transport and metabolism","METABOLISM","K07509|1|3.9e-193|678.3|isc:IscW_ISCW005457|acetyl-CoA acyltransferase [EC:2.3.1.16]","JAW02477.1","165999.243077734;","122682.740164033;",1.3530774,"NA","NA","Non","Ribonuclease 3, partial [Ornithodoros moubata]"]
["JAR86853.1",13.50583945,13.8084334,"GO:0015986//ATP synthesis coupled proton transport","GO:0005524//ATP binding;GO:0046933//proton-transporting ATP synthase activity, rotational mechanism","GO:0045261//proton-transporting ATP synthase complex, catalytic core F(1)",7304361,831.6,{"v":7.2e-241,"d":"7.20E-241"},"KOG1350","F0F1-type ATP synthase, beta subunit",null,"C","Energy production and conversion","METABOLISM","K02133|1|6.4e-269|930.2|isc:IscW_ISCW012509|F-type H+-transporting ATPase subunit beta [EC:7.1.2.2]","JAR86853.1","992947.822994426;","733688.220862806;",1.353364815,"NA","NA","Non","atp synthase subunit mitochondrial, partial [Alectorobius mimon]"]
["JAV99439.1",12.1964602,12.49988499,null,"GO:0004867//serine-type endopeptidase inhibitor activity","GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0016020//membrane;GO:0005615//extracellular space","Hs4826904",191,{"v":3.6e-48,"d":"3.60E-48"},"KOG2392","Serpin",null,"V","Defense mechanisms","CELLULAR PROCESSES AND SIGNALING","K13963|1|6.0e-54|215.7|bfo:BRAFLDRAFT_66649|serpin B!K19821|5|2.3e-50|203.8|ccw:104698153|plasminogen activator inhibitor 2","JAV99439.1","268306.428069132;","198086.720564489;",1.354489727,"NA","NA","Non","Intracellular coagulation inhibitor, partial [Ornithodoros moubata]"]
["JAW04048.1",10.03101733,10.3419935,null,"GO:0051537//2 iron, 2 sulfur cluster binding","GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle","Hs8923930",117.9,{"v":1e-26,"d":"1.00E-26"},"KOG3461","CDGSH-type Zn-finger containing protein",null,"R","General function prediction only","POORLY CHARACTERIZED","K16603|1|8.6e-21|103.6|acep:105624376|tubulin polyglutamylase TTLL9 [EC:6.-.-.-]!K19483|2|6.2e-11|70.9|ccar:109092612|neuron navigator 2 [EC:3.6.4.12]","JAW04048.1","31007.7824851241;","22720.373966446;",1.364756695,"NA","NA","Non","Hematopoietic stem-progenitor cells protein-like protein, partial [Ornithodoros moubata]"]
["XP_064461408.1",10.75921901,11.070627,"GO:0051216//cartilage development;GO:0033339//pectoral fin development;GO:0043010//camera-type eye development","GO:0004029//aldehyde dehydrogenase (NAD) activity;GO:0016491//oxidoreductase activity",null,"Hs4557343",729.9,{"v":3e-210,"d":"3.00E-210"},"KOG2453","Aldehyde dehydrogenase",null,"C","Energy production and conversion","METABOLISM","K14085|1|7.4e-265|916.8|isc:IscW_ISCW020189|aldehyde dehydrogenase family 7 member A1 [EC:1.2.1.31 1.2.1.8 1.2.1.3]","XP_064461408.1","64255.7825667022;","47061.8986317393;",1.36534616,"NA","NA","Non","alpha-aminoadipic semialdehyde dehydrogenase-like [Ornithodoros turicata]"]
["JAV98923.1",13.26612698,13.57935102,"GO:0006950//response to stress;GO:0006457//protein folding","GO:0051082//unfolded protein binding;GO:0005524//ATP binding",null,7301648,1012.3,{"v":4.5e-295,"d":"4.50E-295"},"KOG0020","Endoplasmic reticulum glucose-regulated protein (GRP94/endoplasmin), HSP90 family",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K09487|1|0.0e+00|1256.9|isc:IscW_ISCW022766|heat shock protein 90kDa beta","JAV98923.1","789654.682262488;","577305.564113379;",1.367827943,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW03006.1",9.406118743,9.721952803,null,"GO:0004027//alcohol sulfotransferase activity",null,"CE23282",152.9,{"v":9e-37,"d":"9.00E-37"},"KOG1584","Sulfotransferase",null,"R","General function prediction only","POORLY CHARACTERIZED","K01025|1|3.2e-45|186.4|isc:IscW_ISCW020846|sulfotransferase [EC:2.8.2.-]!K01015|2|4.1e-45|186.0|isc:IscW_ISCW017683|alcohol sulfotransferase [EC:2.8.2.2]!K01016|3|6.6e-35|152.1|isc:IscW_ISCW007984|estrone sulfotransferase [EC:2.8.2.4]","JAW03006.1","16679.7852758252;","12162.5731710248;",1.371402666,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW02196.1",9.294909977,9.612024771,"GO:0046294//formaldehyde catabolic process","GO:0052689//carboxylic ester hydrolase activity;GO:0018738//S-formylglutathione hydrolase activity;GO:0042802//identical protein binding","GO:0005737//cytoplasm;GO:0070062//extracellular exosome","Hs20547663",419.5,{"v":4.5e-117,"d":"4.50E-117"},"KOG3101","Esterase D",null,"R","General function prediction only","POORLY CHARACTERIZED","K01070|1|1.0e-132|476.9|isc:IscW_ISCW023289|S-formylglutathione hydrolase [EC:3.1.2.12]","JAW02196.1","14943.3964336983;","10882.4858886141;",1.373160194,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["AIZ58610.1",9.750915588,10.06890629,"GO:0022900//electron transport chain","GO:0004129//cytochrome-c oxidase activity;GO:0005507//copper ion binding","GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane;GO:0070469//respiratory chain","DmMi004",290.8,{"v":2e-78,"d":"2.00E-78"},"KOG4767","Cytochrome c oxidase, subunit II, and related proteins",null,"C","Energy production and conversion","METABOLISM","K02261|1|7.4e-81|304.3|dpl:AGL76300|cytochrome c oxidase subunit 2","AIZ58610.1","23597.741633315;","17169.942200514;",1.374363487,"NA","NA","Non","cytochrome c oxidase subunit II (mitochondrion) [Ornithodoros moubata] >UYB78472.1 cytochrome c oxidase subunit II (mitochondrion) [Ornithodoros moubata]"]
["JAW03204.1",8.642451002,8.967465642,"GO:0036255//response to methylamine;GO:1990830//cellular response to leukemia inhibitory factor;GO:0006546//glycine catabolic process;GO:1903442//response to lipoic acid;GO:0019464//glycine decarboxylation via glycine cleavage system","GO:0030170//pyridoxal phosphate binding;GO:0004375//glycine dehydrogenase (decarboxylating) activity;GO:0070280//pyridoxal binding;GO:0042803//protein homodimerization activity;GO:0019899//enzyme binding;GO:0016829//lyase activity;GO:0016594//glycine binding","GO:0005960//glycine cleavage complex;GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005886//plasma membrane","Hs18573217",1338.6,0,"KOG2040","Glycine dehydrogenase (decarboxylating)",null,"E","Amino acid transport and metabolism","METABOLISM","K00281|1|0.0e+00|1366.3|isc:IscW_ISCW006033|glycine dehydrogenase [EC:1.4.4.2]","JAW03204.1","7843.69765259058;","5667.20314461411;",1.384050907,"NA","NA","Non","Vesicle amine transport protein, partial [Ornithodoros moubata]"]
["XP_064481211.1",12.52855908,12.85788316,"GO:0007160//cell-matrix adhesion",null,"GO:0016021//integral component of membrane",7302020,414.1,{"v":7.8e-115,"d":"7.80E-115"},"KOG4291","Mucin/alpha-tectorin",null,"W","Extracellular structures","CELLULAR PROCESSES AND SIGNALING","K17495|1|1.3e-72|279.3|spis:111344594|CUB and sushi domain-containing protein!K23091|5|7.1e-71|273.5|mze:101478447|kremen protein","XP_064481211.1","383802.417049089;","276111.232683942;",1.390028263,"NA","NA","Non","protein mesh-like isoform X2 [Ornithodoros turicata]"]
["JAV98805.1",8.247910747,8.577820828,"GO:0042176//regulation of protein catabolic process","GO:0030234//enzyme regulator activity","GO:0000502//proteasome complex","Hs4506225",1313.1,0,"KOG2062","26S proteasome regulatory complex, subunit RPN2/PSMD1",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K03032|1|0.0e+00|1376.3|tut:107363118|26S proteasome regulatory subunit N2","JAV98805.1","5312.51601444784;","3819.63729203627;",1.390843059,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAV99947.1",11.14181424,11.47253694,"GO:0006986//response to unfolded protein;GO:0006457//protein folding;GO:0051085//chaperone cofactor-dependent protein refolding","GO:0051087//chaperone binding;GO:0051082//unfolded protein binding;GO:0046872//metal ion binding;GO:0005524//ATP binding","GO:0005737//cytoplasm;GO:0005759//mitochondrial matrix","Hs4504523",131.7,{"v":6.8e-31,"d":"6.80E-31"},"KOG1641","Mitochondrial chaperonin",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K04078|1|8.0e-43|176.8|isc:IscW_ISCW017823|chaperonin GroES","JAV99947.1","96041.6222773313;","68996.7196870506;",1.391973745,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAV99559.1",11.24016296,11.57145075,"GO:0019859//thymine metabolic process;GO:0006573//valine metabolic process","GO:0004491//methylmalonate-semialdehyde dehydrogenase (acylating) activity;GO:0018478//malonate-semialdehyde dehydrogenase (acetylating) activity","GO:0005739//mitochondrion",7290043,765.4,{"v":6.3e-221,"d":"6.30E-221"},"KOG2449","Methylmalonate semialdehyde dehydrogenase",null,"EG","Amino acid transport and metabolism;Carbohydrate transport and metabolism","METABOLISM;METABOLISM","K00140|1|2.2e-237|825.5|lak:106157712|malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27]","JAV99559.1","106027.179348812;","76127.3563437205;",1.392760559,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["XP_064480623.1",8.841051783,9.172546993,null,"GO:0004857//enzyme inhibitor activity",null,"HsM6912424",157.5,{"v":3.7e-38,"d":"3.70E-38"},"KOG2160","Armadillo/beta-catenin-like repeat-containing protein",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K09562|1|5.5e-77|292.0|isc:IscW_ISCW006573|hsp70-interacting protein","XP_064480623.1","9629.11878024932;","6912.25901342015;",1.393049474,"NA","NA","Non","hsp70-binding protein 1-like [Ornithodoros turicata]"]
["XP_064471144.1",8.535066616,8.868717029,"GO:0005975//carbohydrate metabolic process;GO:0006072//glycerol-3-phosphate metabolic process","GO:0004370//glycerol kinase activity",null,"Hs4504007",711.4,{"v":1.2e-204,"d":"1.20E-204"},"KOG2517","Ribulose kinase and related carbohydrate kinases",null,"G","Carbohydrate transport and metabolism","METABOLISM","K00864|1|4.0e-208|728.4|xtr:100038285|glycerol kinase [EC:2.7.1.30]","XP_064471144.1","7106.15812411192;","5090.17055255479;",1.396055014,"NA","NA","Non","glycerol kinase 3-like isoform X1 [Ornithodoros turicata]"]
["JAW02003.1",9.602419268,9.937640357,"GO:0009058//biosynthetic process","GO:0016844//strictosidine synthase activity;GO:0016788//hydrolase activity, acting on ester bonds","GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0016020//membrane","At3g59530",127.9,{"v":2.2e-29,"d":"2.20E-29"},"KOG1520","Predicted alkaloid synthase/Surface mucin Hemomucin",null,"R","General function prediction only","POORLY CHARACTERIZED","K21407|1|4.3e-57|225.3|isc:IscW_ISCW018608|adipocyte plasma membrane-associated protein","JAW02003.1","20694.854165931;","14800.5447712539;",1.398249489,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["XP_064460863.1",10.37765003,10.71600615,null,"GO:0005388//calcium-transporting ATPase activity;GO:0000166//nucleotide binding","GO:0016021//integral component of membrane",7291680,1618.2,0,"KOG0202","Ca2+ transporting ATPase",null,"P","Inorganic ion transport and metabolism","METABOLISM","K05853|1|0.0e+00|1765.0|isc:IscW_ISCW009225|Ca2+ transporting ATPase, sarcoplasmic/endoplasmic reticulum [EC:3.6.3.8]","XP_064460863.1","45071.5338442515;","32133.3602973584;",1.402639918,"NA","NA","Non","calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type-like [Ornithodoros turicata]"]
["XP_064460162.1",11.47541246,11.81535644,null,null,"GO:0005739//mitochondrion","Hs4503937",242.7,{"v":7.7e-64,"d":"7.70E-64"},"KOG2883","NIPSNAP1 protein",null,"S","Function unknown","POORLY CHARACTERIZED",null,"XP_064460162.1","135314.427742819;","96318.1892758565;",1.404868891,"NA","NA","Non","protein NipSnap-like [Ornithodoros turicata]"]
["JAW06383.1",12.83428467,13.1799467,"GO:0007155//cell adhesion;GO:0030198//extracellular matrix organization",null,"GO:0005578//proteinaceous extracellular matrix;GO:0005615//extracellular space",7299547,292,{"v":3e-78,"d":"3.00E-78"},"KOG1437","Fasciclin and related adhesion glycoproteins",null,"MW","Cell wall/membrane/envelope biogenesis;Extracellular structures","CELLULAR PROCESSES AND SIGNALING;CELLULAR PROCESSES AND SIGNALING","K19519|1|2.7e-276|955.3|isc:IscW_ISCW001538|transforming growth factor-beta-induced protein","JAW06383.1","529636.765693736;","374851.290683895;",1.412925015,"NA","NA","Non","Fasciclin, partial [Ornithodoros moubata]"]
["JAW00852.1",8.673590738,9.020427018,{"$nulls":3},7292359,288.9,{"v":9.4e-78,"d":"9.40E-78"},"KOG0517","Beta-spectrin",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K06115|1|8.2e-93|344.4|clec:106662751|spectrin beta","JAW00852.1","8270.30789736745;","5846.4547934483;",1.41458511,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAV99474.1",11.55544427,11.90354606,"GO:0048147//negative regulation of fibroblast proliferation;GO:0048678//response to axon injury;GO:0048773//erythrophore differentiation;GO:0009791//post-embryonic development;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0055072//iron ion homeostasis;GO:0001889//liver development;GO:0003032//detection of oxygen;GO:0042554//superoxide anion generation;GO:0055093//response to hyperoxia;GO:0010332//response to gamma radiation;GO:0006749//glutathione metabolic process;GO:0022904//respiratory electron transport chain;GO:0048666//neuron development;GO:0007626//locomotory behavior;GO:0014823//response to activity;GO:0050790//regulation of catalytic activity;GO:0045599//negative regulation of fat cell differentiation;GO:0051881//regulation of mitochondrial membrane potential;GO:0001306//age-dependent response to oxidative stress;GO:0007507//heart development;GO:0008631//intrinsic apoptotic signaling pathway in response to oxidative stress;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0042542//response to hydrogen peroxide;GO:0003069//acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure;GO:0001836//release of cytochrome c from mitochondria;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0030097//hemopoiesis","GO:0046872//metal ion binding;GO:0004784//superoxide dismutase activity","GO:0043209//myelin sheath;GO:0005743//mitochondrial inner membrane","Hs10835187",276.2,{"v":4.9e-74,"d":"4.90E-74"},"KOG0876","Manganese superoxide dismutase",null,"P","Inorganic ion transport and metabolism","METABOLISM","K04564|1|9.2e-92|340.5|isc:IscW_ISCW016585|superoxide dismutase, Fe-Mn family [EC:1.15.1.1]","JAV99474.1","147789.767935916;","104343.567665286;",1.416376412,"NA","NA","Non","Superoxide dismutase, partial [Ornithodoros moubata]"]
["JAV99279.1",14.60024004,14.94848844,null,"GO:0005524//ATP binding;GO:0032440//2-alkenal reductase [NAD(P)] activity",null,7292698,1107.4,0,"KOG0100","Molecular chaperones GRP78/BiP/KAR2, HSP70 superfamily",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K09490|1|0.0e+00|1126.3|tut:107362423|heat shock 70kDa protein 5","JAV99279.1","3104888.73951508;","2191813.94297853;",1.416584081,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW03056.1",11.54402844,11.89570788,"GO:0009072//aromatic amino acid family metabolic process","GO:0016034//maleylacetoacetate isomerase activity;GO:0003824//catalytic activity;GO:0016740//transferase activity","GO:0005737//cytoplasm;GO:0005739//mitochondrion","Hs4504189",203.8,{"v":3e-52,"d":"3.00E-52"},"KOG0868","Glutathione S-transferase",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K01800|1|8.4e-58|227.6|isc:IscW_ISCW023198|maleylacetoacetate isomerase [EC:5.2.1.2]","JAW03056.1","146635.894390167;","103159.172252938;",1.421452801,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["XP_064471171.1",9.283656819,9.637437867,"GO:0006810//transport",null,"GO:0016021//integral component of membrane","Hs6679189",243,{"v":4.3e-64,"d":"4.30E-64"},"KOG1693","emp24/gp25L/p24 family of membrane trafficking proteins",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K20349|1|1.0e-89|333.6|isc:IscW_ISCW007906|p24 family protein gamma-3","XP_064471171.1","15328.0209489479;","10760.7100222741;",1.424443268,"NA","NA","Non","transmembrane emp24 domain-containing protein 3-like [Ornithodoros turicata]"]
["QIG55621.1",10.39556403,10.75108174,"GO:0006952//defense response",null,"GO:0016021//integral component of membrane",{"$nulls":10},"QIG55621.1","46680.4974652958;","32714.1841679464;",1.426919199,"NA","NA","Non","defensin A [Ornithodoros turicata]"]
["JAW02613.1",12.28280785,12.64002321,null,null,"GO:0016021//integral component of membrane","Hs4502679",159.1,{"v":9.1e-39,"d":"9.10E-39"},"KOG3882","Tetraspanin family integral membrane protein",null,"R","General function prediction only","POORLY CHARACTERIZED","K06497|1|2.2e-48|196.4|ipu:100305026|CD63 antigen","JAW02613.1","308668.513650327;","215951.22499145;",1.429343657,"NA","NA","Non","GA25794, partial [Ornithodoros moubata]"]
["JAV99940.1",9.751357108,10.11049443,"GO:0045047//protein targeting to ER;GO:0006465//signal peptide processing","GO:0008233//peptidase activity","GO:0005787//signal peptidase complex;GO:0016021//integral component of membrane",7292653,158.3,{"v":1.3e-38,"d":"1.30E-38"},"KOG4072","Signal peptidase complex, subunit SPC25",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K12947|1|7.8e-84|313.9|isc:IscW_ISCW020703|signal peptidase complex subunit 2 [EC:3.4.-.-]","JAV99940.1","24599.8206184654;","17177.5247575713;",1.432093446,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["XP_064471608.1",10.85029305,11.21614363,"GO:0045454//cell redox homeostasis","GO:0004601//peroxidase activity;GO:0051920//peroxiredoxin activity","GO:0005623//cell","Hs5802974",311.6,{"v":1.1e-84,"d":"1.10E-84"},"KOG0852","Alkyl hydroperoxide reductase, thiol specific antioxidant and related enzymes",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K20011|1|5.2e-106|387.9|isc:IscW_ISCW015321|peroxiredoxin 3 [EC:1.11.1.15]","XP_064471608.1","74320.6133932343;","51549.25589824;",1.44173979,"NA","NA","Non","peroxiredoxin-2-like [Ornithodoros turicata]"]
["JAV99799.1",10.7312479,11.09896287,null,"GO:0005524//ATP binding;GO:0032440//2-alkenal reductase [NAD(P)] activity",null,"Hs5453832",786.9,{"v":3.7e-227,"d":"3.70E-227"},"KOG0104","Molecular chaperones GRP170/SIL1, HSP70 superfamily",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K09486|1|0.0e+00|1075.1|isc:IscW_ISCW012646|hypoxia up-regulated 1","JAV99799.1","66102.5674529008;","45763.7648635322;",1.444430275,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAV98745.1",10.51345007,10.88860697,"GO:0006099//tricarboxylic acid cycle","GO:0004591//oxoglutarate dehydrogenase (succinyl-transferring) activity;GO:0030976//thiamine pyrophosphate binding",null,"Hs20541592",1329.3,0,"KOG0450","2-oxoglutarate dehydrogenase, E1 subunit",null,"G","Carbohydrate transport and metabolism","METABOLISM","K00164|1|0.0e+00|1464.1|dpte:113788776|2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]","JAV98745.1","53562.6338297623;","36807.2484674683;",1.455219721,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAV98797.1",11.83544485,12.21490946,"GO:0006486//protein glycosylation;GO:0018279//protein N-linked glycosylation via asparagine","GO:0004579//dolichyl-diphosphooligosaccharide-protein glycotransferase activity","GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0008250//oligosaccharyltransferase complex","Hs4506675",592,{"v":1.1e-168,"d":"1.10E-168"},"KOG2291","Oligosaccharyltransferase, alpha subunit (ribophorin I)",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K12666|1|1.4e-251|872.8|isc:IscW_ISCW016170|oligosaccharyltransferase complex subunit alpha (ribophorin I)","JAV98797.1","201775.195125953;","138060.165876205;",1.461501903,"NA","NA","Non","Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1, partial [Ornithodoros moubata]"]
["JAW03065.1",9.64469109,10.02553924,"GO:0006412//translation","GO:0003735//structural constituent of ribosome","GO:0022625//cytosolic large ribosomal subunit;GO:0005840//ribosome","Hs13904866",82.8,{"v":6.3e-16,"d":"6.30E-16"},"KOG3412","60S ribosomal protein L28",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K02903|1|5.1e-37|158.3|isc:IscW_ISCW002598|large subunit ribosomal protein L28e","JAW03065.1","22596.249861165;","15439.6026800418;",1.463525346,"NA","NA","Non","Prefoldin, partial [Ornithodoros moubata]"]
["JAV99219.1",9.540584849,9.923121046,"GO:0055085//transmembrane transport;GO:0030150//protein import into mitochondrial matrix","GO:0015266//protein channel activity","GO:0005742//mitochondrial outer membrane translocase complex;GO:0005741//mitochondrial outer membrane",7290829,402.9,{"v":5.1e-112,"d":"5.10E-112"},"KOG3296","Translocase of outer mitochondrial membrane complex, subunit TOM40",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K11518|1|3.4e-127|458.8|dpx:DAPPUDRAFT_128731|mitochondrial import receptor subunit TOM40","JAV99219.1","20396.5499617374;","13913.0822932694;",1.465997939,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW03755.1",8.429358456,8.813421014,"GO:0006914//autophagy;GO:0060322//head development",null,null,"Hs6005764",134.4,{"v":7.2e-32,"d":"7.20E-32"},"KOG1654","Microtubule-associated anchor protein involved in autophagy and membrane trafficking",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K08341|1|4.8e-31|137.1|nvl:108558321|GABA(A) receptor-associated protein","JAW03755.1","6723.88246086382;","4579.56116031728;",1.468237289,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAV99223.1",10.07795594,10.46722905,"GO:0033539//fatty acid beta-oxidation using acyl-CoA dehydrogenase","GO:0003995//acyl-CoA dehydrogenase activity;GO:0050660//flavin adenine dinucleotide binding","GO:0005654//nucleoplasm;GO:0005739//mitochondrion","Hs4557233",550.1,{"v":3.3e-156,"d":"3.30E-156"},"KOG0139","Short-chain acyl-CoA dehydrogenase",null,"I","Lipid transport and metabolism","METABOLISM","K00248|1|1.7e-163|579.7|xtr:394882|butyryl-CoA dehydrogenase [EC:1.3.8.1]","JAV99223.1","35144.698072809;","23812.2621826949;",1.475907572,"NA","NA","Non","Medium-chain acyl-CoA dehydrogenase, partial [Ornithodoros moubata]"]
["JAW01721.1",10.0723358,10.4633787,"GO:0009311//oligosaccharide metabolic process;GO:0016139//glycoside catabolic process;GO:0046477//glycosylceramide catabolic process","GO:0008456//alpha-N-acetylgalactosaminidase activity;GO:0004557//alpha-galactosidase activity","GO:0005737//cytoplasm","CE06273",112.1,{"v":4.5e-25,"d":"4.50E-25"},"KOG2366","Alpha-D-galactosidase (melibiase)",null,"G","Carbohydrate transport and metabolism","METABOLISM","K01204|1|3.6e-30|134.4|isc:IscW_ISCW018185|alpha-N-acetylgalactosaminidase [EC:3.2.1.49]","JAW01721.1","35009.6390827214;","23678.8091784867;",1.478521948,"NA","NA","Non","Sodium-potassium-calcium exchanger 5, partial [Ornithodoros moubata]"]
["AAC19132.1",10.8947704,11.28756445,{"$nulls":3},"Hs22062367",234.2,{"v":1.7e-61,"d":"1.70E-61"},"KOG2332","Ferritin",null,"P","Inorganic ion transport and metabolism","METABOLISM",null,"AAC19132.1","79822.7992068052;","53893.7825403522;",1.48111332,"NA","NA","Non","ferritin [Ornithodoros moubata] >JAW03165.1 Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW04485.1",9.523423698,9.922703506,"GO:0005975//carbohydrate metabolic process;GO:0016139//glycoside catabolic process;GO:0009311//oligosaccharide metabolic process;GO:0046477//glycosylceramide catabolic process","GO:0008456//alpha-N-acetylgalactosaminidase activity;GO:0004557//alpha-galactosidase activity;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds","GO:0005737//cytoplasm",7297618,132.9,{"v":4.2e-31,"d":"4.20E-31"},"KOG2366","Alpha-D-galactosidase (melibiase)",null,"G","Carbohydrate transport and metabolism","METABOLISM","K01204|1|4.9e-43|177.9|isc:IscW_ISCW018185|alpha-N-acetylgalactosaminidase [EC:3.2.1.49]","JAW04485.1","20388.0353732319;","13676.354861941;",1.490750685,"NA","NA","Non","Alpha-D-galactosidase, partial [Ornithodoros moubata]"]
["XP_064459221.1",9.562171756,9.966419926,"GO:1902476//chloride transmembrane transport;GO:0006821//chloride transport","GO:0005229//intracellular calcium activated chloride channel activity;GO:0015276//ligand-gated ion channel activity;GO:0005254//chloride channel activity;GO:0008237//metallopeptidase activity","GO:0005634//nucleus;GO:0030054//cell junction;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0016021//integral component of membrane",{"$nulls":9},"K05030|1|1.8e-83|315.1|isc:IscW_ISCW019083|calcium-activated chloride channel regulator 3/4!K05028|3|1.5e-34|152.5|rno:308016|calcium-activated chloride channel regulator 2","XP_064459221.1","21299.0963433232;","14216.687877843;",1.498175702,"NA","NA","Non","calcium-activated chloride channel regulator 2-like [Ornithodoros turicata]"]
["JAW04950.1",11.40400773,11.80838884,"GO:0006810//transport;GO:0006506//GPI anchor biosynthetic process;GO:0006839//mitochondrial transport;GO:0055085//transmembrane transport","GO:0017176//phosphatidylinositol N-acetylglucosaminyltransferase activity;GO:0015114//phosphate ion transmembrane transporter activity","GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane","Hs4505775",498.4,{"v":9.8e-141,"d":"9.80E-141"},"KOG0767","Mitochondrial phosphate carrier protein",null,"C","Energy production and conversion","METABOLISM","K15102|1|4.5e-181|637.9|isc:IscW_ISCW014488|solute carrier family 25 (mitochondrial phosphate transporter), member 3","JAW04950.1","134374.88694221;","89680.4188279101;",1.498374882,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW00370.1",9.343527593,9.748854025,"GO:0006412//translation","GO:0003735//structural constituent of ribosome;GO:0003723//RNA binding","GO:0022627//cytosolic small ribosomal subunit;GO:0015935//small ribosomal subunit",7297568,222.2,{"v":6.6e-58,"d":"6.60E-58"},"KOG0877","40S ribosomal protein S2/30S ribosomal protein S5",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K02981|1|9.7e-65|250.4|bter:100652333|small subunit ribosomal protein S2e","JAW00370.1","17134.5817446204;","11424.6387182099;",1.499791999,"NA","NA","Non","60S ribosomal protein L5, partial [Ornithodoros moubata]"]
["JAW04110.1",15.39629195,15.80486352,"GO:0030490//maturation of SSU-rRNA;GO:0006364//rRNA processing",null,"GO:0032040//small-subunit processome;GO:0005730//nucleolus","Hs21361348_2",186.8,{"v":1e-46,"d":"1.00E-46"},"KOG2172","Uncharacterized conserved protein",null,"S","Function unknown","POORLY CHARACTERIZED","K14567|1|3.8e-52|210.3|myi:110450723|U3 small nucleolar RNA-associated protein 14","JAW04110.1","7310801.85474473;","4858750.91116648;",1.504666938,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW01313.1",7.680652778,8.091974445,"GO:0007034//vacuolar transport",null,"GO:0005622//intracellular","Hs7656922",319.3,{"v":5e-87,"d":"5.00E-87"},"KOG3230","Vacuolar assembly/sorting protein DID4",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K12191|1|6.4e-98|360.9|isc:IscW_ISCW018144|charged multivesicular body protein 2A","JAW01313.1","3268.13395362103;","2166.03324898377;",1.508810613,"NA","NA","Non","Serine hydroxymethyltransferase, partial [Ornithodoros moubata]"]
["JAV99925.1",11.62648818,12.04084498,"GO:0006629//lipid metabolic process","GO:0003995//acyl-CoA dehydrogenase activity;GO:0050660//flavin adenine dinucleotide binding",null,"Hs7656849",538.1,{"v":1.3e-152,"d":"1.30E-152"},"KOG0140","Medium-chain acyl-CoA dehydrogenase",null,"I","Lipid transport and metabolism","METABOLISM","K11538|1|1.6e-185|652.9|isc:IscW_ISCW003911|isobutyryl-CoA dehydrogenase [EC:1.3.99.-]","JAV99925.1","169540.137470032;","112026.214475726;",1.513397005,"NA","NA","Non","Acyl-CoA dehydrogenase, partial [Ornithodoros moubata]"]
["JAW03792.1",13.33354599,13.74816539,null,"GO:0008308//voltage-gated anion channel activity","GO:0005741//mitochondrial outer membrane",7297771,344,{"v":2.5e-94,"d":"2.50E-94"},"KOG3126","Porin/voltage-dependent anion-selective channel protein",null,"P","Inorganic ion transport and metabolism","METABOLISM","K15040|1|4.0e-132|474.9|isc:IscW_ISCW000781|voltage-dependent anion channel protein 2","JAW03792.1","934872.457256735;","617568.942087558;",1.513794483,"NA","NA","Non","Voltage-dependent anion-selective channel, partial [Ornithodoros moubata]"]
["XP_064488842.1",9.374373664,9.79671437,"GO:0019439//aromatic compound catabolic process","GO:0033961//cis-stilbene-oxide hydrolase activity","GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","Hs4503583",291.6,{"v":4e-78,"d":"4.00E-78"},"KOG2565","Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)",null,"R","General function prediction only","POORLY CHARACTERIZED","K01253|1|6.6e-84|316.2|sko:100371948|microsomal epoxide hydrolase [EC:3.3.2.9]","XP_064488842.1","17974.5899416656;","11782.5354113137;",1.525528192,"NA","NA","Non","epoxide hydrolase 1-like [Ornithodoros turicata]"]
["JAV99927.1",9.139595018,9.563164854,null,null,"GO:0016021//integral component of membrane","CE20418",118.2,{"v":1.3e-26,"d":"1.30E-26"},"KOG3472","Predicted small membrane protein",null,"S","Function unknown","POORLY CHARACTERIZED",null,"JAV99927.1","14230.8134577358;","9316.99115856722;",1.527404418,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW04847.1",9.476116084,9.901748141,"GO:0042176//regulation of protein catabolic process","GO:0030234//enzyme regulator activity","GO:0000502//proteasome complex","Hs20149522",1264.2,0,"KOG2005","26S proteasome regulatory complex, subunit RPN1/PSMD2",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K03028|1|0.0e+00|1336.2|zne:110834936|26S proteasome regulatory subunit N1","JAW04847.1","19965.2420129575;","13044.4245567869;",1.530557513,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW00897.1",8.681342315,9.108748126,null,"GO:0004842//ubiquitin-protein transferase activity",null,"Hs18553366_1",120.2,{"v":6.3e-27,"d":"6.30E-27"},"KOG4155","FOG: WD40 repeat",null,"R","General function prediction only","POORLY CHARACTERIZED","K02084|1|1.3e-14|84.7|mmu:11783|apoptotic protease-activating factor","JAW00897.1","9033.97840436308;","5891.95013579201;",1.533274756,"NA","NA","Non","Phosphatidylinositol-glycan biosynthesis class W protein, partial [Ornithodoros moubata]"]
["JAW02857.1",11.08931366,11.53133464,null,null,"GO:0016021//integral component of membrane","HsM5031629",260.4,{"v":6.3e-69,"d":"6.30E-69"},"KOG3776","Plasma membrane glycoprotein CD36 and related membrane receptors",null,"T","Signal transduction mechanisms","CELLULAR PROCESSES AND SIGNALING","K13885|1|5.1e-90|335.9|isc:IscW_ISCW002412|scavenger receptor class B, member 1","JAW02857.1","101857.967046106;","65467.7976325906;",1.555848382,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW06238.1",9.576469667,10.02039355,null,"GO:0000062//fatty-acyl-CoA binding",null,7297350,106.7,{"v":2.1e-23,"d":"2.10E-23"},"KOG0817","Acyl-CoA-binding protein",null,"I","Lipid transport and metabolism","METABOLISM","K08762|1|1.1e-27|126.3|pgc:109864191|diazepam-binding inhibitor (GABA receptor modulator, acyl-CoA-binding protein)","JAW06238.1","22480.2752935898;","14421.4169183897;",1.55881183,"NA","NA","Non","Acyl-CoA-binding domain-containing protein 7, partial [Ornithodoros moubata]"]
["JAV98857.1",12.30207332,12.75109364,"GO:0006635//fatty acid beta-oxidation;GO:0032868//response to insulin","GO:0004300//enoyl-CoA hydratase activity;GO:0016509//long-chain-3-hydroxyacyl-CoA dehydrogenase activity;GO:0003857//3-hydroxyacyl-CoA dehydrogenase activity","GO:0016507//mitochondrial fatty acid beta-oxidation multienzyme complex;GO:0005743//mitochondrial inner membrane;GO:0031012//extracellular matrix;GO:0042645//mitochondrial nucleoid","Hs20127408",917.9,{"v":1.1e-266,"d":"1.10E-266"},"KOG1683","Hydroxyacyl-CoA dehydrogenase/enoyl-CoA hydratase",null,"I","Lipid transport and metabolism","METABOLISM","K07515|1|0.0e+00|1111.3|isc:IscW_ISCW005458|enoyl-CoA hydratase / long-chain 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.211]","JAV98857.1","344928.91642386;","220151.961601185;",1.566776484,"NA","NA","Non","Hydroxyacyl-CoA dehydrogenase, partial [Ornithodoros moubata]"]
["pdb|3L0R|A",10.60425166,11.06430135,"GO:2000117//negative regulation of cysteine-type endopeptidase activity","GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0002020//protease binding","GO:0005615//extracellular space",{"$nulls":9},"K13899|1|3.6e-23|111.7|isc:IscW_ISCW018604|cystatin-C!K13902|3|3.4e-13|78.6|isc:IscW_ISCW018602|cystatin-M","pdb|3L0R|A","63850.6055964392;","40305.8402936992;",1.584152697,"NA","NA","Non","Chain A, Cystatin-2 >pdb|3L0R|B Chain B, Cystatin-2"]
["JAW00795.1",10.08670624,10.55169612,{"$nulls":3},7291892,812,{"v":6.4e-235,"d":"6.40E-235"},"KOG0161","Myosin class II heavy chain",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K10352|1|2.2e-243|845.5|bter:100649130|myosin heavy chain","JAW00795.1","38242.2466498193;","24021.5407574759;",1.591998075,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW01647.1",8.925392125,9.392000368,null,"GO:0003723//RNA binding",null,7292558,283.1,{"v":4.5e-76,"d":"4.50E-76"},"KOG2193","IGF-II mRNA-binding protein IMP, contains RRM and KH domains",null,"AR","RNA processing and modification;General function prediction only","INFORMATION STORAGE AND PROCESSING;POORLY CHARACTERIZED","K17391|1|5.1e-99|364.8|isc:IscW_ISCW009590|insulin-like growth factor 2 mRNA-binding protein 1","JAW01647.1","11992.0638937829;","7520.53174055548;",1.594576595,"NA","NA","Non","Transmembrane protein C2orf18, partial [Ornithodoros moubata]"]
["XP_064466438.1",9.239117932,9.710409583,"GO:0006810//transport",null,"GO:0005622//intracellular",7295554,169.1,{"v":5e-42,"d":"5.00E-42"},"KOG2104","Nuclear transport factor 2",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K17265|1|6.7e-10|67.8|srx:107717399|Ras GTPase-activating protein-binding protein 1 [EC:3.6.4.12 3.6.4.13]","XP_064466438.1","16488.353837701;","10291.9563449928;",1.602062162,"NA","NA","Non","probable nuclear transport factor 2 [Ornithodoros turicata]"]
["JAW05494.1",12.31528048,12.79513822,{"$nulls":3},"Hs4507761",262.7,{"v":3.2e-70,"d":"3.20E-70"},"KOG0003","Ubiquitin/60s ribosomal protein L40 fusion",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K02927|1|1.8e-63|245.7|cge:100756515|large subunit ribosomal protein L40e","JAW05494.1","360460.70028394;","223078.828625297;",1.615844509,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW05496.1",8.846979768,9.327873083,null,"GO:0004721//phosphoprotein phosphatase activity",null,7302983,64.3,{"v":4.8e-10,"d":"4.80E-10"},"KOG4194","Membrane glycoprotein LIG-1",null,"T","Signal transduction mechanisms","CELLULAR PROCESSES AND SIGNALING","K13023|1|7.1e-09|65.9|pvt:110087108|carboxypeptidase N regulatory subunit!K04309|5|2.1e-08|64.3|mdo:100030781|leucine-rich repeat-containing G protein-coupled receptor 4","JAW05496.1","11247.1842027995;","6953.35647267063;",1.617518712,"NA","NA","Non","Membrane glycoprotein LIG-1, partial [Ornithodoros moubata]"]
["JAV98808.1",13.798182,14.28158488,null,"GO:0005544//calcium-dependent phospholipid binding;GO:0005509//calcium ion binding",null,"Hs4502111",350.1,{"v":6.3e-96,"d":"6.30E-96"},"KOG0819","Annexin",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K17095|1|2.8e-107|393.3|sko:100367736|annexin A7/11","JAV98808.1","1593725.44368433;","982820.715536931;",1.621583081,"NA","NA","Non","Annexin, partial [Ornithodoros moubata]"]
["JAW06411.1",11.64021493,12.12401598,"GO:0006665//sphingolipid metabolic process","GO:0016787//hydrolase activity;GO:0008047//enzyme activator activity;GO:0001664//G-protein coupled receptor binding","GO:0005737//cytoplasm;GO:0005764//lysosome",7301992,281.6,{"v":5.8e-75,"d":"5.80E-75"},"KOG1340","Prosaposin",null,"IG","Lipid transport and metabolism;Carbohydrate transport and metabolism","METABOLISM;METABOLISM","K12382|1|1.7e-167|594.3|isc:IscW_ISCW011597|saposin","JAW06411.1","184243.950999575;","113574.572626824;",1.622228873,"NA","NA","Non","Saposin, partial [Ornithodoros moubata]"]
["JAW01686.1",11.08662299,11.57308322,"GO:0006811//ion transport",null,"GO:0005921//gap junction;GO:0016021//integral component of membrane;GO:0005886//plasma membrane",{"$nulls":9},"K22037|1|8.3e-31|136.7|isc:IscW_ISCW013694|innexin","JAW01686.1","106200.407183924;","65291.8823088616;",1.626548407,"NA","NA","Non","General transcription factor IIE TFIIE subunit, partial [Ornithodoros moubata]"]
["JAW03394.1",10.76349561,11.26140406,null,null,"GO:0016020//membrane",7291688,421.8,{"v":1.2e-117,"d":"1.20E-117"},"KOG2620","Prohibitins and stomatins of the PID superfamily",null,"C","Energy production and conversion","METABOLISM","K03364|1|3.0e-100|369.4|dse:Dsec_GM16067|cell division cycle 20-like protein 1, cofactor of APC complex!K05288|3|5.6e-62|242.3|nni:104014593|phosphatidylinositol glycan, class O!K17286|4|9.3e-25|118.6|sanh:107701117|erythrocyte band 7 integral membrane protein","JAW03394.1","77761.6815754676;","47263.594649463;",1.6452765,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["XP_064472124.1",8.224979397,8.739020771,null,"GO:0008289//lipid binding","GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum",7301181,580.9,{"v":3.3e-165,"d":"3.30E-165"},"KOG1012","Ca2+-dependent lipid-binding protein CLB1/vesicle protein vp115/Granuphilin A, contains C2 domain",null,"R","General function prediction only","POORLY CHARACTERIZED","K19513|1|2.9e-23|114.8|tsp:Tsp_01622|protein CLEC16A!K17598|2|3.1e-17|94.7|els:105012423|synaptotagmin-like protein","XP_064472124.1","6241.78058755093;","3733.04449044209;",1.672034878,"NA","NA","Non","extended synaptotagmin-2-like [Ornithodoros turicata]"]
["JAR86924.1",10.30239785,10.81803887,"GO:0006096//glycolytic process","GO:0004332//fructose-bisphosphate aldolase activity",null,"Hs4557305",489.2,{"v":5.6e-138,"d":"5.60E-138"},"KOG1557","Fructose-biphosphate aldolase",null,"G","Carbohydrate transport and metabolism","METABOLISM","K01623|1|1.8e-147|526.2|nvi:100118253|fructose-bisphosphate aldolase, class I [EC:4.1.2.13]","JAR86924.1","49913.1050323937;","29803.9987693607;",1.674711686,"NA","NA","Non","fructose bisphosphate aldolase, partial [Alectorobius mimon]"]
["JAW01723.1",10.46862181,10.98445022,"GO:0008104//protein localization;GO:0001766//membrane raft polarization",null,"GO:0016021//integral component of membrane;GO:0045121//membrane raft","CE09769",77,{"v":2.6e-14,"d":"2.60E-14"},"KOG4788","Members of chemokine-like factor super family and related proteins",null,"V","Defense mechanisms","CELLULAR PROCESSES AND SIGNALING",null,"JAW01723.1","58950.3131082589;","35193.6803256782;",1.675025532,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAV99519.1",9.272973804,9.793868114,"GO:0000422//autophagy of mitochondrion;GO:0006612//protein targeting to membrane;GO:0000045//autophagosome assembly;GO:0006501//C-terminal protein lipidation;GO:0044804//autophagy of nucleus;GO:0015031//protein transport;GO:0006914//autophagy;GO:0051697//protein delipidation","GO:0004197//cysteine-type endopeptidase activity","GO:0005737//cytoplasm;GO:0005829//cytosol","Hs18378733",383.3,{"v":5.1e-106,"d":"5.10E-106"},"KOG2674","Cysteine protease required for autophagy - Apg4p/Aut2p",null,"ZU","Cytoskeleton;Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING;CELLULAR PROCESSES AND SIGNALING","K08342|1|8.3e-152|540.8|isc:IscW_ISCW004712|cysteine protease ATG4 [EC:3.4.22.-]","JAV99519.1","17923.5024106324;","10646.3650618503;",1.683532577,"NA","NA","Non","Cystein protease, partial [Ornithodoros moubata]"]
["JAW01204.1",8.763078382,9.285861521,"GO:0005975//carbohydrate metabolic process;GO:0006032//chitin catabolic process","GO:0008061//chitin binding;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0004568//chitinase activity","GO:0005737//cytoplasm;GO:0005615//extracellular space;GO:0016021//integral component of membrane;GO:0005576//extracellular region",{"$nulls":9},"K17523|1|1.3e-09|68.2|ocu:100352595|chitinase-3-like protein 1/2!K01183|2|5.1e-09|66.2|tca:658736|chitinase [EC:3.2.1.14]","JAW01204.1","10784.4603584991;","6393.76376184307;",1.686715487,"NA","NA","Non","Sushi nidogen and EGF-like domain-containing protein 1, partial [Ornithodoros moubata]"]
["XP_064474748.1",9.996107166,10.52129627,"GO:0006355//regulation of transcription, DNA-templated","GO:0003700//DNA binding transcription factor activity;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0003676//nucleic acid binding;GO:0046872//metal ion binding","GO:0005622//intracellular","Hs18589727",69.3,{"v":4.6e-12,"d":"4.60E-12"},"KOG1721","FOG: Zn-finger",null,"R","General function prediction only","POORLY CHARACTERIZED","K09228|1|5.2e-11|71.2|mcf:102145632|KRAB domain-containing zinc finger protein","XP_064474748.1","37097.1812990762;","21940.8871009572;",1.690778551,"NA","NA","Non","zinc finger protein 14-like [Ornithodoros turicata]"]
["JAW02470.1",8.922302118,9.447895729,"GO:0006099//tricarboxylic acid cycle;GO:0002244//hematopoietic progenitor cell differentiation","GO:0030976//thiamine pyrophosphate binding;GO:0004591//oxoglutarate dehydrogenase (succinyl-transferring) activity","GO:0045252//oxoglutarate dehydrogenase complex;GO:0005739//mitochondrion","Hs18375678",916,{"v":5e-266,"d":"5.00E-266"},"KOG0451","Predicted 2-oxoglutarate dehydrogenase, E1 subunit",null,"G","Carbohydrate transport and metabolism","METABOLISM","K15791|1|0.0e+00|1160.2|isc:IscW_ISCW021407|probable 2-oxoglutarate dehydrogenase E1 component DHKTD1 [EC:1.2.4.2]","JAW02470.1","12681.4519562303;","7497.32911596019;",1.691462621,"NA","NA","Non","High-affinity copper uptake protein, partial [Ornithodoros moubata]"]
["JAW01139.1",10.96564118,11.49592311,"GO:0006810//transport",null,"GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","Hs5803201",188,{"v":1.5e-47,"d":"1.50E-47"},"KOG1691","emp24/gp25L/p24 family of membrane trafficking proteins",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K20352|1|6.0e-71|271.2|isc:IscW_ISCW001550|p24 family protein delta-1","JAW01139.1","98314.1365888062;","57851.8773242545;",1.699411344,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAT79078.1",9.607213283,10.14396741,null,"GO:0004129//cytochrome-c oxidase activity","GO:0016021//integral component of membrane",7298641,89.4,{"v":4e-18,"d":"4.00E-18"},"KOG4075","Cytochrome c oxidase, subunit IV/COX5b",null,"C","Energy production and conversion","METABOLISM","K02263|1|9.8e-20|100.1|fcd:110855865|cytochrome c oxidase subunit 4","JAT79078.1","25437.1863570088;","14871.6691564512;",1.710445955,"NA","NA","Non","cytochrome c oxidase polypeptide iv, partial [Ornithodoros brasiliensis]"]
["XP_064484524.1",9.674208886,10.22673662,"GO:0019859//thymine metabolic process;GO:0006573//valine metabolic process","GO:0004491//methylmalonate-semialdehyde dehydrogenase (acylating) activity;GO:0018478//malonate-semialdehyde dehydrogenase (acetylating) activity","GO:0005739//mitochondrion",7290043,758.1,{"v":1e-218,"d":"1.00E-218"},"KOG2449","Methylmalonate semialdehyde dehydrogenase",null,"EG","Amino acid transport and metabolism;Carbohydrate transport and metabolism","METABOLISM;METABOLISM","K00140|1|1.7e-237|825.9|lak:106157712|malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27]","XP_064484524.1","27632.1885524334;","15902.1386605361;",1.737639769,"NA","NA","Non","probable methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial [Ornithodoros turicata]"]
["XP_064490246.1",8.82517387,9.379881396,"GO:0055085//transmembrane transport","GO:0042626//ATPase activity, coupled to transmembrane movement of substances;GO:0008514//organic anion transmembrane transporter activity;GO:0032440//2-alkenal reductase [NAD(P)] activity;GO:0005524//ATP binding","GO:0016021//integral component of membrane;GO:0005887//integral component of plasma membrane","Hs4826838",1300.4,0,"KOG0054","Multidrug resistance-associated protein/mitoxantrone resistance protein, ABC superfamily",null,"Q","Secondary metabolites biosynthesis, transport and catabolism","METABOLISM","K05665|1|0.0e+00|2150.2|isc:IscW_ISCW007915|ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3]","XP_064490246.1","11847.6094956891;","6803.37349407755;",1.741431586,"NA","NA","Non","multidrug resistance-associated protein 1-like [Ornithodoros turicata]"]
["JAW01845.1",9.405332908,9.961694332,"GO:0006751//glutathione catabolic process","GO:0036374//glutathione hydrolase activity",null,"Hs18373328",93.6,{"v":1.8e-19,"d":"1.80E-19"},"KOG2410","Gamma-glutamyltransferase",null,"E","Amino acid transport and metabolism","METABOLISM","K18592|1|6.6e-22|107.1|acep:105620280|gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]","JAW01845.1","21198.682920258;","12153.0191491326;",1.744314121,"NA","NA","Non","GTP-binding protein 6, partial [Ornithodoros moubata]"]
["XP_064459600.1",10.35067178,10.91152922,"GO:0006084//acetyl-CoA metabolic process","GO:0003986//acetyl-CoA hydrolase activity;GO:0003824//catalytic activity;GO:0016740//transferase activity",null,7301882,563.1,{"v":4.3e-160,"d":"4.30E-160"},"KOG2828","Acetyl-CoA hydrolase",null,"C","Energy production and conversion","METABOLISM","K18118|1|2.0e-11|74.7|lve:103069380|succinyl-CoA:acetate CoA-transferase [EC:2.8.3.18]","XP_064459600.1","54804.5893255683;","31278.0478612968;",1.752174227,"NA","NA","Non","4-hydroxybutyrate coenzyme A transferase-like [Ornithodoros turicata]"]
["JAV99709.1",10.93454508,11.49580364,"GO:0055085//transmembrane transport","GO:0042626//ATPase activity, coupled to transmembrane movement of substances;GO:0008514//organic anion transmembrane transporter activity;GO:0032440//2-alkenal reductase [NAD(P)] activity;GO:0005524//ATP binding","GO:0016021//integral component of membrane;GO:0005887//integral component of plasma membrane","Hs9955970",1182.5,0,"KOG0054","Multidrug resistance-associated protein/mitoxantrone resistance protein, ABC superfamily",null,"Q","Secondary metabolites biosynthesis, transport and catabolism","METABOLISM","K05665|1|0.0e+00|1887.8|isc:IscW_ISCW007915|ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3]","JAV99709.1","98302.3923287985;","56080.5919956729;",1.752877222,"NA","NA","Non","ABC transporter, partial [Ornithodoros moubata]"]
["JAW05226.1",9.062051748,9.631385801,"GO:0089711//L-glutamate transmembrane transport;GO:0043490//malate-aspartate shuttle;GO:0015810//aspartate transport","GO:0005313//L-glutamate transmembrane transporter activity;GO:0005509//calcium ion binding;GO:0015183//L-aspartate transmembrane transporter activity","GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane",7301942,849,{"v":5.6e-246,"d":"5.60E-246"},"KOG0751","Mitochondrial aspartate/glutamate carrier protein Aralar/Citrin (contains EF-hand Ca2+-binding domains)",null,"C","Energy production and conversion","METABOLISM","K15105|1|2.3e-271|938.7|dpte:113791591|solute carrier family 25 (mitochondrial aspartate/glutamate transporter), member 12/13","JAW05226.1","15235.5349013879;","8621.82232755542;",1.767089871,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAT79203.1",8.458372484,9.029368745,"GO:0007030//Golgi organization;GO:0000278//mitotic cell cycle;GO:0008283//cell proliferation","GO:0003924//GTPase activity;GO:0016779//nucleotidyltransferase activity;GO:0003746//translation elongation factor activity;GO:0005525//GTP binding","GO:0005739//mitochondrion;GO:0005622//intracellular",7303306,417.5,{"v":1.8e-116,"d":"1.80E-116"},"KOG0460","Mitochondrial translation elongation factor Tu",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K02358|1|2.3e-138|495.7|isc:IscW_ISCW010766|elongation factor Tu","JAT79203.1","8344.59034191566;","4714.37902479579;",1.770029584,"NA","NA","Non","translation elongation, partial [Ornithodoros brasiliensis]"]
["XP_064486579.1",11.23438924,11.80611387,"GO:0007155//cell adhesion;GO:0030198//extracellular matrix organization",null,"GO:0005578//proteinaceous extracellular matrix;GO:0005615//extracellular space",7299547,292,{"v":3e-78,"d":"3.00E-78"},"KOG1437","Fasciclin and related adhesion glycoproteins",null,"MW","Cell wall/membrane/envelope biogenesis;Extracellular structures","CELLULAR PROCESSES AND SIGNALING;CELLULAR PROCESSES AND SIGNALING","K19519|1|6.5e-278|960.7|isc:IscW_ISCW001538|transforming growth factor-beta-induced protein","XP_064486579.1","134069.536182012;","75689.0845458095;",1.771319299,"NA","NA","Non","transforming growth factor-beta-induced protein ig-h3-like [Ornithodoros turicata]"]
["JAW02784.1",9.924558601,10.49669863,"GO:0099132//ATP hydrolysis coupled cation transmembrane transport;GO:0015986//ATP synthesis coupled proton transport","GO:0016787//hydrolase activity;GO:0015078//hydrogen ion transmembrane transporter activity","GO:0000276//mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)",7294882,239.2,{"v":8e-63,"d":"8.00E-63"},"KOG3976","Mitochondrial F1F0-ATP synthase, subunit b/ATP4",null,"C","Energy production and conversion","METABOLISM","K02127|1|5.8e-101|371.3|isc:IscW_ISCW012060|F-type H+-transporting ATPase subunit b","JAW02784.1","36195.8093434912;","20425.8922009118;",1.772055242,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW04324.1",8.88783404,9.460023226,"GO:0006574//valine catabolic process","GO:0008442//3-hydroxyisobutyrate dehydrogenase activity;GO:0004616//phosphogluconate dehydrogenase (decarboxylating) activity;GO:0051287//NAD binding","GO:0005739//mitochondrion","Hs20539653",353.2,{"v":4.1e-97,"d":"4.10E-97"},"KOG0409","Predicted dehydrogenase",null,"R","General function prediction only","POORLY CHARACTERIZED","K00020|1|2.2e-101|372.9|aplc:110987285|3-hydroxyisobutyrate dehydrogenase [EC:1.1.1.31]","JAW04324.1","12836.1825818307;","7243.31345454117;",1.772142358,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW00053.1",9.151004848,9.737428283,"GO:0005975//carbohydrate metabolic process;GO:0016139//glycoside catabolic process;GO:0009311//oligosaccharide metabolic process;GO:0046477//glycosylceramide catabolic process","GO:0008456//alpha-N-acetylgalactosaminidase activity;GO:0004557//alpha-galactosidase activity;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds","GO:0005737//cytoplasm",7297618,343.2,{"v":6.1e-94,"d":"6.10E-94"},"KOG2366","Alpha-D-galactosidase (melibiase)",null,"G","Carbohydrate transport and metabolism","METABOLISM","K01204|1|5.0e-115|418.7|isc:IscW_ISCW018185|alpha-N-acetylgalactosaminidase [EC:3.2.1.49]","JAW00053.1","16939.9206349941;","9423.90521307492;",1.797547859,"NA","NA","Non","Alpha-D-galactosidase, partial [Ornithodoros moubata]"]
["JAW02326.1",11.72959358,12.32645976,"GO:0045454//cell redox homeostasis","GO:0004601//peroxidase activity;GO:0051920//peroxiredoxin activity","GO:0005623//cell",7292861,314.3,{"v":1.4e-85,"d":"1.40E-85"},"KOG0852","Alkyl hydroperoxide reductase, thiol specific antioxidant and related enzymes",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K13279|1|4.9e-97|357.8|isc:IscW_ISCW010532|peroxiredoxin 1 [EC:1.11.1.15]","JAW02326.1","225586.682291406;","124193.185529844;",1.816417554,"NA","NA","Non","Proteasome subunit alpha type, partial [Ornithodoros moubata]"]
["JAW01491.1",7.559872185,8.157349243,"GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0007346//regulation of mitotic cell cycle",null,"GO:0012505//endomembrane system","Hs13376788",177.6,{"v":3.1e-44,"d":"3.10E-44"},"KOG2607","CDK5 activator-binding protein",null,"T","Signal transduction mechanisms","CELLULAR PROCESSES AND SIGNALING","K20349|1|8.2e-40|168.3|nvi:100117556|p24 family protein gamma-3","JAW01491.1","3488.92604176432;","1919.60014462203;",1.817527495,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["XP_064469238.1",12.29509165,12.90444142,null,"GO:0004222//metalloendopeptidase activity","GO:0016021//integral component of membrane","Hs7662200",66.6,{"v":1.8e-10,"d":"1.80E-10"},"KOG3624","M13 family peptidase",null,"E","Amino acid transport and metabolism","METABOLISM","K01415|1|9.0e-18|96.3|isc:IscW_ISCW013494|endothelin-converting enzyme [EC:3.4.24.71]!K08635|2|1.3e-16|92.4|lak:106151033|neprilysin [EC:3.4.24.11]","XP_064469238.1","402094.10201096;","218620.285075614;",1.839235101,"NA","NA","Non","neprilysin-1-like [Ornithodoros turicata]"]
["JAR87658.1",10.80663795,11.41978001,"GO:0051216//cartilage development;GO:0033339//pectoral fin development;GO:0043010//camera-type eye development","GO:0004029//aldehyde dehydrogenase (NAD) activity;GO:0016491//oxidoreductase activity",null,"Hs4557343",727.6,{"v":1.5e-209,"d":"1.50E-209"},"KOG2453","Aldehyde dehydrogenase",null,"C","Energy production and conversion","METABOLISM","K14085|1|9.8e-265|916.4|isc:IscW_ISCW020189|aldehyde dehydrogenase family 7 member A1 [EC:1.2.1.31 1.2.1.8 1.2.1.3]","JAR87658.1","91106.0970091281;","49347.2813288047;",1.846223228,"NA","NA","Non","aldehyde dehydrogenase 7 member a1, partial [Alectorobius mimon]"]
["JAV98952.1",11.9387932,12.55656302,"GO:0006487//protein N-linked glycosylation","GO:0004579//dolichyl-diphosphooligosaccharide-protein glycotransferase activity;GO:0016740//transferase activity","GO:0016021//integral component of membrane;GO:0008250//oligosaccharyltransferase complex",7302715,399.4,{"v":1.1e-110,"d":"1.10E-110"},"KOG2447","Oligosaccharyltransferase, delta subunit (ribophorin II)",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K12667|1|3.2e-185|652.5|isc:IscW_ISCW005017|oligosaccharyltransferase complex subunit delta (ribophorin II)","JAV98952.1","283952.718464286;","153091.826986565;",1.854786921,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW06798.1",10.4218699,11.05013051,"GO:0019752//carboxylic acid metabolic process","GO:0016831//carboxy-lyase activity;GO:0030170//pyridoxal phosphate binding","GO:0016021//integral component of membrane",7302829,486.5,{"v":5.6e-137,"d":"5.60E-137"},"KOG1383","Glutamate decarboxylase/sphingosine phosphate lyase",null,"E","Amino acid transport and metabolism","METABOLISM","K01634|1|1.9e-148|530.0|xma:102224894|sphinganine-1-phosphate aldolase [EC:4.1.2.27]","JAW06798.1","62952.1697058561;","33586.178229534;",1.874347515,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAV99145.1",9.517172426,10.15958861,"GO:0006810//transport;GO:0055085//transmembrane transport",null,"GO:0016021//integral component of membrane","CE00474",434.1,{"v":2e-121,"d":"2.00E-121"},"KOG0756","Mitochondrial tricarboxylate/dicarboxylate carrier proteins",null,"C","Energy production and conversion","METABOLISM","K15100|1|1.2e-140|503.4|dpte:113796954|solute carrier family 25 (mitochondrial citrate transporter), member 1","JAV99145.1","25837.6656232687;","13591.1269206171;",1.901068673,"NA","NA","Non","AAEL005991-PA, partial [Ornithodoros moubata]"]
["JAR87676.1",8.747227992,9.392220694,"GO:0006486//protein glycosylation;GO:0043686//co-translational protein modification;GO:0018279//protein N-linked glycosylation via asparagine","GO:0004576//oligosaccharyl transferase activity;GO:0004579//dolichyl-diphosphooligosaccharide-protein glycotransferase activity","GO:0016021//integral component of membrane","Hs20558683",1174.5,0,"KOG2292","Oligosaccharyltransferase, STT3 subunit",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K07151|1|0.0e+00|1192.6|zne:110831010|dolichyl-diphosphooligosaccharide---protein glycosyltransferase [EC:2.4.99.18]","JAR87676.1","11994.7063522846;","6293.21905526348;",1.905973119,"NA","NA","Non","dolichyl diphosphooligosaccharide protein glycosyltransferase subunit stt3a, partial [Alectorobius mimon]"]
["JAV98699.1",11.20317167,11.84994559,null,null,"GO:0016020//membrane",7302549,442.6,{"v":5.3e-124,"d":"5.30E-124"},"KOG3090","Prohibitin-like protein",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K17081|1|3.8e-141|505.0|isc:IscW_ISCW021457|prohibitin 2","JAV98699.1","140076.72517591;","73362.7560406348;",1.909371086,"NA","NA","Non","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAT79097.1",10.25402738,10.91115413,"GO:0005975//carbohydrate metabolic process","GO:0032450//maltose alpha-glucosidase activity;GO:0003824//catalytic activity;GO:0004558//alpha-1,4-glucosidase activity","GO:0016021//integral component of membrane",7304049,88.2,{"v":2.4e-17,"d":"2.40E-17"},"KOG0471","Alpha-amylase",null,"G","Carbohydrate transport and metabolism","METABOLISM","K14210|1|4.5e-27|125.9|isc:IscW_ISCW021396|solute carrier family 3 (neutral and basic amino acid transporter), member 1","JAT79097.1","54784.036870555;","28396.6761795288;",1.929241173,"NA","NA","Non","neutral and basic amino acid transport protein rbat, partial [Ornithodoros brasiliensis]"]
["XP_064481593.1",9.579420218,10.23843044,"GO:0005975//carbohydrate metabolic process;GO:0016139//glycoside catabolic process;GO:0009311//oligosaccharide metabolic process;GO:0046477//glycosylceramide catabolic process","GO:0008456//alpha-N-acetylgalactosaminidase activity;GO:0004557//alpha-galactosidase activity;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds","GO:0005737//cytoplasm",7297618,384,{"v":7.2e-106,"d":"7.20E-106"},"KOG2366","Alpha-D-galactosidase (melibiase)",null,"G","Carbohydrate transport and metabolism","METABOLISM","K01204|1|6.9e-136|489.2|isc:IscW_ISCW018185|alpha-N-acetylgalactosaminidase [EC:3.2.1.49]","XP_064481593.1","27957.2109481443;","14464.0308890516;",1.932878266,"NA","NA","Non","uncharacterized protein LOC135394668 isoform X3 [Ornithodoros turicata]"]
["XP_064481101.1",10.1590269,10.81968458,"GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006412//translation","GO:0003735//structural constituent of ribosome","GO:0022627//cytosolic small ribosomal subunit;GO:0005840//ribosome","Hs4506743",346.3,{"v":3.6e-95,"d":"3.60E-95"},"KOG3283","40S ribosomal protein S8",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K02995|1|3.0e-113|411.8|isc:IscW_ISCW015393|small subunit ribosomal protein S8e","XP_064481101.1","49995.3148524471;","25823.1563142866;",1.936065222,"NA","NA","Non","small ribosomal subunit protein eS8-like [Ornithodoros turicata]"]
["JAW02769.1",10.77773628,11.44542325,"GO:0006511//ubiquitin-dependent protein catabolic process","GO:0043130//ubiquitin binding;GO:0008270//zinc ion binding;GO:0042802//identical protein binding","GO:0005776//autophagosome;GO:0016235//aggresome","Hs4505571_1",72.4,{"v":2e-12,"d":"2.00E-12"},"KOG4582","Uncharacterized conserved protein, contains ZZ-type Zn-finger",null,"R","General function prediction only","POORLY CHARACTERIZED","K14381|1|1.6e-84|317.4|isc:IscW_ISCW015997|sequestosome 1","JAW02769.1","93472.565400664;","47941.4752503842;",1.949722342,"NA","NA","Non","Docking protein, partial [Ornithodoros moubata]"]
["JAW06027.1",9.731293124,10.40767945,"GO:0030148//sphingolipid biosynthetic process;GO:0046513//ceramide biosynthetic process","GO:0042284//sphingolipid delta-4 desaturase activity","GO:0016021//integral component of membrane",7297049,385.2,{"v":9.8e-107,"d":"9.80E-107"},"KOG2987","Fatty acid desaturase",null,"I","Lipid transport and metabolism","METABOLISM","K04712|1|3.9e-135|485.0|isc:IscW_ISCW010259|sphingolipid 4-desaturase/C4-monooxygenase [EC:1.14.19.17 1.14.18.5]","JAW06027.1","33112.9410914904;","16836.3096899935;",1.966757663,"NA","NA","Non","hypothetical protein, partial [Ornithodoros moubata]"]
["JAV98685.1",8.837315104,9.537227373,"GO:0006086//acetyl-CoA biosynthetic process from pyruvate","GO:0004739//pyruvate dehydrogenase (acetyl-transferring) activity","GO:0043231//intracellular membrane-bounded organelle;GO:0005739//mitochondrion","CE01643",483.8,{"v":2.8e-136,"d":"2.80E-136"},"KOG0225","Pyruvate dehydrogenase E1, alpha subunit",null,"C","Energy production and conversion","METABOLISM","K00161|1|1.7e-176|622.9|isc:IscW_ISCW019126|pyruvate dehydrogenase E1 component alpha subunit [EC:1.2.4.1]","JAV98685.1","13866.4477909994;","6886.47831942539;",2.013576047,"NA","NA","Up","Pyruvate dehydrogenase E1 component subunit alpha, partial [Ornithodoros moubata]"]
["JAW05001.1",11.47473521,12.1850005,null,"GO:0004029//aldehyde dehydrogenase (NAD) activity;GO:0016491//oxidoreductase activity",null,"Hs4557343",443.4,{"v":4e-124,"d":"4.00E-124"},"KOG2453","Aldehyde dehydrogenase",null,"C","Energy production and conversion","METABOLISM","K14085|1|1.5e-155|553.1|isc:IscW_ISCW020189|aldehyde dehydrogenase family 7 member A1 [EC:1.2.1.31 1.2.1.8 1.2.1.3]","JAW05001.1","195829.663497094;","96252.9792851639;",2.03453093,"NA","NA","Up","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW06078.1",9.19156032,9.906472259,"GO:0055085//transmembrane transport","GO:0042626//ATPase activity, coupled to transmembrane movement of substances;GO:0008514//organic anion transmembrane transporter activity;GO:0032440//2-alkenal reductase [NAD(P)] activity;GO:0005524//ATP binding","GO:0005887//integral component of plasma membrane","Hs9955958",912.9,{"v":4.2e-265,"d":"4.20E-265"},"KOG0054","Multidrug resistance-associated protein/mitoxantrone resistance protein, ABC superfamily",null,"Q","Secondary metabolites biosynthesis, transport and catabolism","METABOLISM","K05665|1|0.0e+00|1258.4|isc:IscW_ISCW021900|ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3]","JAW06078.1","20059.7833060189;","9813.95194810162;",2.044006677,"NA","NA","Up","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAV99253.1",8.498382234,9.225342391,"GO:0009791//post-embryonic development;GO:0006650//glycerophospholipid metabolic process;GO:0006083//acetate metabolic process;GO:0051289//protein homotetramerization;GO:0042135//neurotransmitter catabolic process;GO:0022904//respiratory electron transport chain;GO:0006541//glutamine metabolic process;GO:0006105//succinate metabolic process;GO:0009450//gamma-aminobutyric acid catabolic process;GO:0006536//glutamate metabolic process;GO:0006681//galactosylceramide metabolic process;GO:0006749//glutathione metabolic process;GO:0006678//glucosylceramide metabolic process;GO:0006006//glucose metabolic process;GO:0046459//short-chain fatty acid metabolic process;GO:0007417//central nervous system development","GO:0009013//succinate-semialdehyde dehydrogenase [NAD(P)+] activity;GO:0004777//succinate-semialdehyde dehydrogenase (NAD+) activity","GO:0005739//mitochondrion","Hs4507229",547.7,{"v":1.7e-155,"d":"1.70E-155"},"KOG2451","Aldehyde dehydrogenase",null,"C","Energy production and conversion","METABOLISM","K00139|1|8.2e-158|560.8|pbi:103063078|succinate-semialdehyde dehydrogenase [EC:1.2.1.24]","JAV99253.1","10151.1511375881;","4906.82432290966;",2.068782265,"NA","NA","Up","Succinate-semialdehyde dehydrogenase, partial [Ornithodoros moubata]"]
["XP_064477046.1",15.62429896,16.36502993,null,"GO:0005319//lipid transporter activity",null,7297541,288.9,{"v":1.5e-76,"d":"1.50E-76"},"KOG4338","Predicted lipoprotein",null,"I","Lipid transport and metabolism","METABOLISM","K14462|1|1.0e-80|308.1|hmg:100199505|apolipoprotein B","XP_064477046.1","12800949.8018079;","6103048.5242668;",2.097468134,"NA","NA","Up","uncharacterized protein LOC135390962 [Ornithodoros turicata]"]
["JAV98688.1",9.804648053,10.55652131,"GO:0006511//ubiquitin-dependent protein catabolic process","GO:0004298//threonine-type endopeptidase activity","GO:0005737//cytoplasm;GO:0019773//proteasome core complex, alpha-subunit complex;GO:0005634//nucleus","Hs4506189",391.3,{"v":1.2e-108,"d":"1.20E-108"},"KOG0183","20S proteasome, regulatory subunit alpha type PSMA7/PRE6",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K02731|1|3.4e-127|458.4|isc:IscW_ISCW007139|20S proteasome subunit alpha 4 [EC:3.4.25.1]","JAV98688.1","38427.2187449394;","18117.7618326745;",2.120969417,"NA","NA","Up","Proteasome subunit alpha type, partial [Ornithodoros moubata]"]
["JAV99715.1",10.60654416,11.39798442,null,"GO:0017174//glycine N-methyltransferase activity",{"$nulls":10},"K00552|1|3.5e-126|455.3|isc:IscW_ISCW020587|glycine N-methyltransferase [EC:2.1.1.20]","JAV99715.1","89141.8695228533;","40398.347489798;",2.206572176,"NA","NA","Up","Glycine N-methyltransferase, partial [Ornithodoros moubata]"]
["XP_064486172.1",9.187100037,9.982107541,"GO:0009058//biosynthetic process","GO:0016844//strictosidine synthase activity;GO:0016788//hydrolase activity, acting on ester bonds","GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0016020//membrane","Hs14772303",248.1,{"v":5.4e-65,"d":"5.40E-65"},"KOG1520","Predicted alkaloid synthase/Surface mucin Hemomucin",null,"R","General function prediction only","POORLY CHARACTERIZED","K21407|1|1.5e-142|511.1|isc:IscW_ISCW018608|adipocyte plasma membrane-associated protein","XP_064486172.1","21635.8629990417;","9770.27641945166;",2.214457613,"NA","NA","Up","uncharacterized protein LOC135398717 [Ornithodoros turicata]"]
["JAW05151.1",9.229256006,10.03373054,"GO:0045454//cell redox homeostasis",null,"GO:0005623//cell",7295434,337.8,{"v":1.8e-92,"d":"1.80E-92"},"KOG0908","Thioredoxin-like protein",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K03671|1|2.2e-82|309.7|isc:IscW_ISCW001465|thioredoxin 1!K01456|2|5.6e-25|119.0|spis:111323412|peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase [EC:3.5.1.52]","JAW05151.1","22782.1027757857;","10190.9566849898;",2.2355215,"NA","NA","Up","Thioredoxin-like protein 1, partial [Ornithodoros moubata]"]
["JAW00242.1",9.243983335,10.06170128,"GO:0000028//ribosomal small subunit assembly;GO:0006412//translation","GO:0003735//structural constituent of ribosome","GO:0022627//cytosolic small ribosomal subunit;GO:0005840//ribosome","Hs4506693",102.4,{"v":3.2e-22,"d":"3.20E-22"},"KOG0187","40S ribosomal protein S17",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K02962|1|8.8e-31|136.3|isc:IscW_ISCW001811|small subunit ribosomal protein S17e","JAW00242.1","23428.3306827051;","10342.152872712;",2.265324345,"NA","NA","Up","Ribosomal protein S17, partial [Ornithodoros moubata]"]
["AAL17868.1",12.21669506,13.04145343,"GO:0016998//cell wall macromolecule catabolic process;GO:0050830//defense response to Gram-positive bacterium;GO:0008152//metabolic process;GO:0050829//defense response to Gram-negative bacterium","GO:0003796//lysozyme activity","GO:0005615//extracellular space",{"$nulls":9},"K13915|1|2.6e-42|175.6|bfo:BRAFLDRAFT_287383|lysozyme C [EC:3.2.1.17]","AAL17868.1","461138.36919928;","202135.806033079;",2.28132946,"NA","NA","Up","lysozyme precursor [Ornithodoros moubata]"]
["JAV99381.1",10.81044141,11.64961719,"GO:0018279//protein N-linked glycosylation via asparagine","GO:0016757//transferase activity, transferring glycosyl groups","GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","Hs20070197",370.9,{"v":2.1e-102,"d":"2.10E-102"},"KOG2754","Oligosaccharyltransferase, beta subunit",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K12670|1|1.1e-138|496.9|isc:IscW_ISCW017658|oligosaccharyltransferase complex subunit beta","JAV99381.1","114647.466194407;","49535.3287438253;",2.314458571,"NA","NA","Up","Uncharacterized protein, partial [Ornithodoros moubata]"]
["XP_064483779.1",9.339177533,10.20624395,"GO:0006457//protein folding;GO:0045454//cell redox homeostasis;GO:0034976//response to endoplasmic reticulum stress","GO:0003756//protein disulfide isomerase activity","GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005623//cell",7291650,272.3,{"v":9.2e-73,"d":"9.20E-73"},"KOG0913","Thiol-disulfide isomerase and thioredoxin",null,"OC","Posttranslational modification, protein turnover, chaperones;Energy production and conversion","CELLULAR PROCESSES AND SIGNALING;METABOLISM","K16458|1|3.6e-32|142.9|hmg:100199716|centrosomal protein CEP104!K09585|2|6.2e-16|89.0|epa:110232436|thioredoxin domain-containing protein 10 [EC:5.3.4.1]!K09584|5|4.9e-13|79.3|nve:NEMVE_v1g239368|protein disulfide-isomerase A6 [EC:5.3.4.1]","XP_064483779.1","27071.6937435696;","11375.0487950553;",2.379918911,"NA","NA","Up","thioredoxin-related transmembrane protein 1-like [Ornithodoros turicata]"]
["XP_064483747.1",9.005572875,9.887052451,"GO:0006090//pyruvate metabolic process;GO:0006094//gluconeogenesis","GO:0046872//metal ion binding;GO:0004736//pyruvate carboxylase activity;GO:0009374//biotin binding;GO:0004075//biotin carboxylase activity;GO:0005524//ATP binding",null,7303838,1758.4,0,"KOG0369","Pyruvate carboxylase",null,"C","Energy production and conversion","METABOLISM","K01958|1|0.0e+00|1783.5|ame:412876|pyruvate carboxylase [EC:6.4.1.1]","XP_064483747.1","19673.9843647685;","8148.3674648986;",2.414469457,"NA","NA","Up","pyruvate carboxylase, mitochondrial-like isoform X2 [Ornithodoros turicata]"]
["JAV99258.1",9.723425832,10.61404895,"GO:1905344//prostaglandin catabolic process;GO:0052651//monoacylglycerol catabolic process","GO:0016787//hydrolase activity;GO:0047372//acylglycerol lipase activity","GO:0016021//integral component of membrane","Hs15100151",370.2,{"v":3.8e-102,"d":"3.80E-102"},"KOG1553","Predicted alpha/beta hydrolase BAT5",null,"R","General function prediction only","POORLY CHARACTERIZED","K08869|1|3.9e-57|226.1|dpl:KGM_201356|aarF domain-containing kinase","JAV99258.1","40702.6691214161;","16704.3731971968;",2.436647496,"NA","NA","Up","Abhydrolase domain-containing protein 16A, partial [Ornithodoros moubata]"]
["JAV99912.1",9.214761587,10.11528095,"GO:0055085//transmembrane transport",null,"GO:0016021//integral component of membrane",7299538,408.7,{"v":8.6e-114,"d":"8.60E-114"},"KOG0750","Mitochondrial solute carrier protein",null,"C","Energy production and conversion","METABOLISM","K15107|1|3.3e-124|448.7|tut:107363627|solute carrier family 25 (mitochondrial glutamate transporter), member 18/22","JAV99912.1","24717.850431542;","10044.3100315019;",2.460880872,"NA","NA","Up","Mitochondrial glutamate carrier 2, partial [Ornithodoros moubata]"]
["JAW02075.1",8.328945538,9.239443918,"GO:0061060//negative regulation of peptidoglycan recognition protein signaling pathway",null,"GO:0005737//cytoplasm;GO:0016021//integral component of membrane;GO:0005886//plasma membrane",7298704,711.4,{"v":8.4e-205,"d":"8.40E-205"},"KOG1278","Endosomal membrane proteins, EMP70",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K17086|1|1.4e-218|762.7|isc:IscW_ISCW021262|transmembrane 9 superfamily member 2/4","JAW02075.1","10295.3119291817;","4142.04761811199;",2.485560978,"NA","NA","Up","Uncharacterized protein, partial [Ornithodoros moubata]"]
["XP_064484126.1",9.351210225,10.41800019,"GO:0005975//carbohydrate metabolic process","GO:0032450//maltose alpha-glucosidase activity;GO:0003824//catalytic activity;GO:0004558//alpha-1,4-glucosidase activity","GO:0016021//integral component of membrane",7297881,239.6,{"v":1.5e-62,"d":"1.50E-62"},"KOG0471","Alpha-amylase",null,"G","Carbohydrate transport and metabolism","METABOLISM","K14210|1|8.0e-120|435.3|isc:IscW_ISCW021396|solute carrier family 3 (neutral and basic amino acid transporter), member 1","XP_064484126.1","33456.4606967133;","11512.7480312155;",2.90603604,"NA","NA","Up","maltase 1-like [Ornithodoros turicata]"]
["JAW03193.1",9.785720576,10.87436361,"GO:0006952//defense response",null,"GO:0016021//integral component of membrane",{"$nulls":10},"JAW03193.1","52805.1290592707;","17778.0632765082;",2.97024081,"NA","NA","Up","Rad1 DNA damage checkpoint protein, partial [Ornithodoros moubata]"]
["AFI98408.1",9.199118912,10.29933919,"GO:0000028//ribosomal small subunit assembly;GO:0006412//translation","GO:0003735//structural constituent of ribosome","GO:0022627//cytosolic small ribosomal subunit;GO:0005840//ribosome","Hs4506695",184.5,{"v":1.3e-46,"d":"1.30E-46"},"KOG3411","40S ribosomal protein S19",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K02966|1|1.1e-58|229.9|isc:IscW_ISCW020743|small subunit ribosomal protein S19e","AFI98408.1","29712.9778192838;","9888.41265840415;",3.004827857,"NA","NA","Up","40S ribosomal protein S19 [Antricola delacruzi]"]
["AAQ82934.1",12.71419803,13.82080517,null,"GO:0004252//serine-type endopeptidase activity",null,"Hs4503137",133.7,{"v":5.4e-31,"d":"5.40E-31"},"KOG3627","Trypsin",null,"E","Amino acid transport and metabolism","METABOLISM","K01310|1|1.9e-44|183.7|isc:IscW_ISCW014005|chymotrypsin [EC:3.4.21.1]!K09632|2|3.7e-35|152.9|acyg:106033190|chymotrypsin-like protease [EC:3.4.21.-]","AAQ82934.1","1005308.65665245;","332434.466505448;",3.024080707,"NA","NA","Up","serine protease-like protein precursor [Ornithodoros moubata] >JAW06965.1 Serine protease-like protein, partial [Ornithodoros moubata]"]
["JAW02557.1",9.306134372,10.41562792,"GO:0006099//tricarboxylic acid cycle","GO:0004449//isocitrate dehydrogenase (NAD+) activity;GO:0000287//magnesium ion binding;GO:0051287//NAD binding","GO:0005739//mitochondrion",7293593,537,{"v":2.5e-152,"d":"2.50E-152"},"KOG0785","Isocitrate dehydrogenase, alpha subunit",null,"E","Amino acid transport and metabolism","METABOLISM","K00030|1|8.9e-177|623.6|isc:IscW_ISCW004116|isocitrate dehydrogenase (NAD+) [EC:1.1.1.41]","JAW02557.1","33377.1869416619;","11005.3233129421;",3.032822026,"NA","NA","Up","Vitellogenin 1, partial [Ornithodoros moubata]"]
["JAW02418.1",10.10317344,11.32804063,"GO:0030301//cholesterol transport;GO:0035855//megakaryocyte development;GO:0055113//epiboly involved in gastrulation with mouth forming second;GO:0043009//chordate embryonic development;GO:0001666//response to hypoxia","GO:0005319//lipid transporter activity;GO:0005509//calcium ion binding","GO:0016021//integral component of membrane","Hs4557803",900.2,{"v":3.1e-261,"d":"3.10E-261"},"KOG1933","Cholesterol transport protein (Niemann-Pick C disease protein)",null,"I","Lipid transport and metabolism","METABOLISM","K20371|1|0.0e+00|1246.5|isc:IscW_ISCW020300|nucleobindin!K12385|2|1.6e-273|946.4|pret:103479869|Niemann-Pick C1 protein","JAW02418.1","83120.0002039451;","24420.3832586891;",3.403713993,"NA","NA","Up","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW04295.1",9.432974002,10.70822401,null,"GO:0017128//phospholipid scramblase activity;GO:0046872//metal ion binding","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","Hs10863877",178.7,{"v":7.5e-45,"d":"7.50E-45"},"KOG0621","Phospholipid scramblase",null,"M","Cell wall/membrane/envelope biogenesis","CELLULAR PROCESSES AND SIGNALING",null,"JAW04295.1","44722.1421090248;","12493.6276121458;",3.579596215,"NA","NA","Up","Uncharacterized protein, partial [Ornithodoros moubata]"]
["XP_064466652.1",10.41933814,11.91960757,"GO:0055114//oxidation-reduction process","GO:0004497//monooxygenase activity;GO:0050660//flavin adenine dinucleotide binding;GO:0004499//N,N-dimethylaniline monooxygenase activity;GO:0050661//NADP binding","GO:0016021//integral component of membrane","At1g62600",248.1,{"v":2.8e-65,"d":"2.80E-65"},"KOG1399","Flavin-containing monooxygenase",null,"Q","Secondary metabolites biosynthesis, transport and catabolism","METABOLISM","K05631|1|2.6e-74|283.5|pgc:109856921|atrophin-1 interacting protein 3 (BAI1-associated protein 1)!K00485|2|4.0e-59|233.0|dme:Dmel_CG3006|dimethylaniline monooxygenase (N-oxide forming) [EC:1.14.13.8]","XP_064466652.1","150182.660912469;","33501.2535904924;",4.482896752,"NA","NA","Up","uncharacterized protein LOC135377864 [Ornithodoros turicata]"]
["XP_064472622.1",12.08565779,13.73790598,{"$nulls":13},"XP_064472622.1","925330.246000542;","177310.514227531;",5.218699241,"NA","NA","Up","uncharacterized protein LOC135387269 [Ornithodoros turicata]"]
["XP_064479579.1",8.935244421,10.61260522,"GO:0006355//regulation of transcription, DNA-templated;GO:0007623//circadian rhythm","GO:0003700//DNA binding transcription factor activity;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0005634//nucleus",7296965,120.9,{"v":4.5e-27,"d":"4.50E-27"},"KOG3119","Basic region leucine zipper transcription factor",null,"K","Transcription","INFORMATION STORAGE AND PROCESSING","K12114|1|1.1e-116|424.1|isc:IscW_ISCW018094|vrille","XP_064479579.1","40643.947821378;","7594.99245085801;",5.351413854,"NA","NA","Up","nuclear factor interleukin-3-regulated protein-like [Ornithodoros turicata] >XP_064479580.1 nuclear factor interleukin-3-regulated protein-like [Ornithodoros turicata]"]
["JAV98665.1",9.06846877,10.76810688,{"$nulls":3},7291522,147.1,{"v":5.3e-35,"d":"5.30E-35"},"KOG2521","Uncharacterized conserved protein",null,"S","Function unknown","POORLY CHARACTERIZED",null,"JAV98665.1","47482.043210816;","8677.32664521473;",5.471966788,"NA","NA","Up","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW06758.1",10.23477787,11.94887156,"GO:0006417//regulation of translation","GO:0005344//oxygen carrier activity;GO:0019825//oxygen binding;GO:0020037//heme binding;GO:0005506//iron ion binding","GO:0005833//hemoglobin complex","Hs4504345",237.3,{"v":1.7e-62,"d":"1.70E-62"},"KOG3378","Globins and related hemoproteins",null,"C","Energy production and conversion","METABOLISM","K13822|1|6.0e-74|280.8|ocu:100009249|hemoglobin subunit alpha","JAW06758.1","154642.543650363;","27855.2816056387;",5.551641726,"NA","NA","Up","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAV99911.1",8.244769279,10.00729982,null,"GO:0005509//calcium ion binding",null,"Hs21281683",79.7,{"v":4.4e-15,"d":"4.40E-15"},"KOG4065","Uncharacterized conserved protein",null,"S","Function unknown","POORLY CHARACTERIZED","K20364|1|2.7e-31|139.0|isc:IscW_ISCW010587|multiple coagulation factor deficiency protein 2","JAV99911.1","22187.8432194;","3807.65685188577;",5.827164601,"NA","NA","Up","Multiple coagulation factor deficiency 2-like protein, partial [Ornithodoros moubata]"]
["JAW05927.1",11.01364713,12.84502546,"GO:0006412//translation","GO:0003735//structural constituent of ribosome","GO:0016021//integral component of membrane;GO:0022627//cytosolic small ribosomal subunit;GO:0005840//ribosome","Hs14165469",187.6,{"v":1.1e-47,"d":"1.10E-47"},"KOG1754","40S ribosomal protein S15/S22",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K02957|1|2.4e-50|201.8|isc:IscW_ISCW015484|small subunit ribosomal protein S15Ae","JAW05927.1","378899.188495907;","60696.8527321475;",6.24248493,"NA","NA","Up","40S ribosomal protein S15a, partial [Ornithodoros moubata]"]
["XP_064484796.1",10.12412852,12.00459021,"GO:0000398//mRNA splicing, via spliceosome;GO:0001649//osteoblast differentiation","GO:0004004//ATP-dependent RNA helicase activity;GO:0004386//helicase activity;GO:0042802//identical protein binding;GO:0003676//nucleic acid binding;GO:0005524//ATP binding;GO:0003723//RNA binding","GO:0046540//U4/U6 x U5 tri-snRNP complex;GO:0071013//catalytic step 2 spliceosome;GO:0016020//membrane;GO:0005654//nucleoplasm;GO:0019013//viral nucleocapsid;GO:0030529//intracellular ribonucleoprotein complex;GO:0005682//U5 snRNP","Hs22042312",3127,0,"KOG0951","RNA helicase BRR2, DEAD-box superfamily",null,"A","RNA processing and modification","INFORMATION STORAGE AND PROCESSING","K12854|1|0.0e+00|3656.7|isc:IscW_ISCW018611|pre-mRNA-splicing helicase BRR2 [EC:3.6.4.13]","XP_064484796.1","163503.587826114;","24937.5136499958;",6.556531261,"NA","NA","Up","LOW QUALITY PROTEIN: U5 small nuclear ribonucleoprotein 200 kDa helicase-like [Ornithodoros turicata]"]
["JAV99931.1",8.554480692,10.68685766,"GO:0009113//purine nucleobase biosynthetic process;GO:0006189//'de novo' IMP biosynthetic process","GO:0004641//phosphoribosylformylglycinamidine cyclo-ligase activity;GO:0004644//phosphoribosylglycinamide formyltransferase activity;GO:0004637//phosphoribosylamine-glycine ligase activity;GO:0046872//metal ion binding;GO:0005524//ATP binding","GO:0005737//cytoplasm;GO:0005829//cytosol","Hs4503915_1",897.9,{"v":1.5e-260,"d":"1.50E-260"},"KOG0237","Glycinamide ribonucleotide synthetase (GARS)/Aminoimidazole ribonucleotide synthetase (AIRS)",null,"F","Nucleotide transport and metabolism","METABOLISM","K11787|1|0.0e+00|1629.4|isc:IscW_ISCW017017|phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.4.13 2.1.2.2 6.3.3.1]","JAV99931.1","43776.7291784112;","5189.95700342865;",8.434892457,"NA","NA","Up","Uncharacterized protein, partial [Ornithodoros moubata]"]
["JAW02365.1",10.586984,12.7211994,"GO:0019516//lactate oxidation;GO:0022904//respiratory electron transport chain","GO:0050660//flavin adenine dinucleotide binding;GO:0016614//oxidoreductase activity, acting on CH-OH group of donors;GO:0071949//FAD binding;GO:0004458//D-lactate dehydrogenase (cytochrome) activity;GO:0051990//(R)-2-hydroxyglutarate dehydrogenase activity","GO:0005739//mitochondrion",7290268,349.7,{"v":5.2e-96,"d":"5.20E-96"},"KOG1232","Proteins containing the FAD binding domain",null,"C","Energy production and conversion","METABOLISM","K18204|1|9.4e-133|477.2|isc:IscW_ISCW005219|D-2-hydroxyglutarate dehydrogenase [EC:1.1.99.39]","JAW02365.1","334770.131517267;","39615.8276014863;",8.45041368,"NA","NA","Up","Integrator complex subunit 2, partial [Ornithodoros moubata]"]
["JAW02894.1",7.856206872,10.48675316,"GO:0006629//lipid metabolic process;GO:0042761//very long-chain fatty acid biosynthetic process","GO:0003865//3-oxo-5-alpha-steroid 4-dehydrogenase activity;GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors;GO:0016491//oxidoreductase activity","GO:0005737//cytoplasm;GO:0016021//integral component of membrane","CE20509",365.2,{"v":1.1e-100,"d":"1.10E-100"},"KOG1639","Steroid reductase required for elongation of the very long chain fatty acids",null,"I","Lipid transport and metabolism","METABOLISM","K10258|1|2.3e-130|469.2|isc:IscW_ISCW002618|very-long-chain enoyl-CoA reductase [EC:1.3.1.93]","JAW02894.1","35837.6094132587;","2581.70902686408;",13.88135109,"NA","NA","Up","Uncharacterized protein, partial [Ornithodoros moubata]"]
["XP_064487710.1",7.728365491,10.47803098,null,"GO:0004222//metalloendopeptidase activity","GO:0016021//integral component of membrane","CE18259",82.4,{"v":4.8e-15,"d":"4.80E-15"},"KOG3624","M13 family peptidase",null,"E","Amino acid transport and metabolism","METABOLISM","K01415|1|2.1e-122|444.5|isc:IscW_ISCW012489|endothelin-converting enzyme [EC:3.4.24.71]!K08635|3|1.9e-38|165.6|isc:IscW_ISCW007149|neprilysin [EC:3.4.24.11]","XP_064487710.1","35526.3865230567;","2271.88574550345;",15.63740016,"NA","NA","Up","neprilysin-like [Ornithodoros turicata]"]
["JAR86927.1",10.42069524,13.55106859,"GO:0042060//wound healing;GO:0006164//purine nucleotide biosynthetic process","GO:0003937//IMP cyclohydrolase activity;GO:0004643//phosphoribosylaminoimidazolecarboxamide formyltransferase activity",null,7301227,662.1,{"v":6.5e-190,"d":"6.50E-190"},"KOG2555","AICAR transformylase/IMP cyclohydrolase/methylglyoxal synthase",null,"F","Nucleotide transport and metabolism","METABOLISM","K00602|1|7.1e-208|727.2|isc:IscW_ISCW007783|phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]","JAR86927.1","767634.194748197;","33546.7489328361;",22.88252123,"NA","NA","Up","a chain crystal structures of transition state analogue inhibitors of inosine monophosphate cyclohydrolase, partial [Alectorobius mimon]"]
["AAS55947.1",null,null,"GO:0000028//ribosomal small subunit assembly;GO:0006412//translation","GO:0003735//structural constituent of ribosome;GO:0019843//rRNA binding;GO:0003723//RNA binding;GO:0003729//mRNA binding","GO:0015935//small ribosomal subunit;GO:0022627//cytosolic small ribosomal subunit","Hs13904870",354.4,{"v":1.3e-97,"d":"1.30E-97"},"KOG3291","Ribosomal protein S7",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K02989|1|6.6e-108|394.0|isc:IscW_ISCW012831|small subunit ribosomal protein S5e"]
["JAW03198.1",null,10.76544442,null,"GO:0005319//lipid transporter activity","GO:0016021//integral component of membrane","Hs4557803",105.9,{"v":9.1e-23,"d":"9.10E-23"},"KOG1933","Cholesterol transport protein (Niemann-Pick C disease protein)",null,"I","Lipid transport and metabolism","METABOLISM","K12385|1|1.5e-44|183.7|isc:IscW_ISCW011287|Niemann-Pick C1 protein"]
["ABI52737.1",null,null,"GO:0006412//translation","GO:0003735//structural constituent of ribosome;GO:0046872//metal ion binding","GO:0005840//ribosome","Hs7705706",156,{"v":2.8e-38,"d":"2.80E-38"},"KOG1779","40s ribosomal protein S27",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K02978|1|2.6e-39|164.9|obi:106868654|small subunit ribosomal protein S27e"]
["ABI52753.1",9.96265359,null,"GO:0002181//cytoplasmic translation;GO:0006412//translation","GO:0003735//structural constituent of ribosome;GO:0003723//RNA binding","GO:0005840//ribosome;GO:0022625//cytosolic large ribosomal subunit","Hs15431293",327,{"v":2.2e-89,"d":"2.20E-89"},"KOG1678","60s ribosomal protein L15",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K02877|1|3.7e-108|394.8|isc:IscW_ISCW008173|large subunit ribosomal protein L15e"]
["ABR23373.1",9.743379757,null,"GO:0000028//ribosomal small subunit assembly;GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0043249//erythrocyte maturation;GO:0048821//erythrocyte development;GO:0043009//chordate embryonic development;GO:0006412//translation","GO:0003735//structural constituent of ribosome;GO:0070181//small ribosomal subunit rRNA binding;GO:0048027//mRNA 5'-UTR binding","GO:0022627//cytosolic small ribosomal subunit;GO:0005840//ribosome","Hs5032051",268.5,{"v":7e-72,"d":"7.00E-72"},"KOG0407","40S ribosomal protein S14",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K02955|1|5.1e-78|294.3|isc:IscW_ISCW023299|small subunit ribosomal protein S14e"]
["ABR23382.1",9.536620338,null,"GO:0006412//translation","GO:0003735//structural constituent of ribosome;GO:0003723//RNA binding","GO:0005840//ribosome;GO:0022625//cytosolic large ribosomal subunit;GO:0016020//membrane","Hs11415026",257.3,{"v":1.9e-68,"d":"1.90E-68"},"KOG0829","60S ribosomal protein L18A",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K02882|1|8.3e-88|327.0|isc:IscW_ISCW010039|large subunit ribosomal protein L18Ae"]
["JAW01488.1",8.81457445,null,"GO:0006412//translation","GO:0003735//structural constituent of ribosome;GO:0003729//mRNA binding","GO:0022627//cytosolic small ribosomal subunit;GO:0005840//ribosome","Hs15011936",183.3,{"v":2.4e-46,"d":"2.40E-46"},"KOG1768","40s ribosomal protein S26",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K02976|1|1.1e-57|226.5|isc:IscW_ISCW013037|small subunit ribosomal protein S26e"]
["ABR23395.1",10.00731042,null,"GO:0042254//ribosome biogenesis;GO:0006412//translation","GO:0019843//rRNA binding;GO:0003735//structural constituent of ribosome;GO:0003723//RNA binding","GO:0015935//small ribosomal subunit;GO:0005829//cytosol;GO:0005840//ribosome","Hs11968182",275,{"v":7.6e-74,"d":"7.60E-74"},"KOG3311","Ribosomal protein S18",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K02964|1|1.4e-75|286.2|bfo:BRAFLDRAFT_114927|small subunit ribosomal protein S18e"]
["XP_064481883.1",null,9.27298322,"GO:0030218//erythrocyte differentiation;GO:0043009//chordate embryonic development;GO:0006412//translation","GO:0003735//structural constituent of ribosome;GO:0003723//RNA binding","GO:0015935//small ribosomal subunit","Hs15718687",401,{"v":1.4e-111,"d":"1.40E-111"},"KOG3181","40S ribosomal protein S3",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K02985|1|3.2e-114|415.2|myi:110456667|small subunit ribosomal protein S3e"]
["JAW04948.1",9.467487541,null,"GO:0006412//translation;GO:0000027//ribosomal large subunit assembly","GO:0019843//rRNA binding;GO:0003735//structural constituent of ribosome","GO:0005840//ribosome;GO:0022625//cytosolic large ribosomal subunit","CE28042",108.6,{"v":4.3e-24,"d":"4.30E-24"},"KOG0886","40S ribosomal protein S2",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K02870|1|1.8e-25|118.6|isc:IscW_ISCW004058|large subunit ribosomal protein L12e"]
["ABR23483.1",null,null,"GO:0000028//ribosomal small subunit assembly;GO:0000461//endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0007155//cell adhesion;GO:0000447//endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006412//translation;GO:0006407//rRNA export from nucleus","GO:0003735//structural constituent of ribosome;GO:0043236//laminin binding;GO:0005055//laminin receptor activity","GO:0022627//cytosolic small ribosomal subunit;GO:0005634//nucleus;GO:0030686//90S preribosome;GO:0005886//plasma membrane","Hs9845502",379,{"v":7.3e-105,"d":"7.30E-105"},"KOG0830","40S ribosomal protein SA (P40)/Laminin receptor 1",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K02998|1|6.8e-106|387.9|egz:104132800|small subunit ribosomal protein SAe"]
["ACB70397.1",9.017248139,null,"GO:0000028//ribosomal small subunit assembly","GO:0003735//structural constituent of ribosome;GO:0016787//hydrolase activity;GO:0003723//RNA binding","GO:0022627//cytosolic small ribosomal subunit;GO:0005840//ribosome","Hs4506679",194.9,{"v":9.3e-50,"d":"9.30E-50"},"KOG3344","40s ribosomal protein s10",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K02947|1|7.5e-71|270.4|isc:IscW_ISCW023883|small subunit ribosomal protein S10e"]
["AFI98432.1",9.210054984,null,"GO:0042274//ribosomal small subunit biogenesis;GO:0006364//rRNA processing;GO:0002181//cytoplasmic translation;GO:0006412//translation","GO:0003735//structural constituent of ribosome","GO:0032040//small-subunit processome;GO:0022627//cytosolic small ribosomal subunit;GO:0030686//90S preribosome;GO:0005840//ribosome","Hs4506741",259.6,{"v":3.8e-69,"d":"3.80E-69"},"KOG3320","40S ribosomal protein S7",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K02993|1|3.8e-72|275.0|isc:IscW_ISCW015731|small subunit ribosomal protein S7e"]
["XP_064472123.1",9.810074002,null,"GO:0006511//ubiquitin-dependent protein catabolic process","GO:0004298//threonine-type endopeptidase activity","GO:0005737//cytoplasm;GO:0019773//proteasome core complex, alpha-subunit complex;GO:0005634//nucleus","Hs4506181",401.4,{"v":1.1e-111,"d":"1.10E-111"},"KOG0181","20S proteasome, regulatory subunit alpha type PSMA2/PRE8",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K02726|1|1.0e-117|426.8|zne:110840301|20S proteasome subunit alpha 2 [EC:3.4.25.1]"]
["JAR86651.1",null,9.424660657,"GO:0035042//fertilization, exchange of chromosomal proteins;GO:0050848//regulation of calcium-mediated signaling;GO:0007274//neuromuscular synaptic transmission;GO:0006334//nucleosome assembly","GO:0042393//histone binding","GO:0005634//nucleus;GO:0005759//mitochondrial matrix",7302739,115.5,{"v":1.1e-25,"d":"1.10E-25"},"KOG4024","Complement component 1, Q subcomponent binding protein/mRNA splicing factor SF2, subunit P32",null,"V","Defense mechanisms","CELLULAR PROCESSES AND SIGNALING","K15414|1|8.8e-60|234.2|isc:IscW_ISCW020550|complement component 1 Q subcomponent-binding protein, mitochondrial"]
["JAR86658.1",9.308240462,null,"GO:0006635//fatty acid beta-oxidation","GO:0050660//flavin adenine dinucleotide binding;GO:0043958//acryloyl-CoA reductase activity;GO:0070991//medium-chain-acyl-CoA dehydrogenase activity;GO:0003995//acyl-CoA dehydrogenase activity;GO:0005524//ATP binding","GO:0005739//mitochondrion",7295201,334.7,{"v":1.1e-91,"d":"1.10E-91"},"KOG0140","Medium-chain acyl-CoA dehydrogenase",null,"I","Lipid transport and metabolism","METABOLISM","K00249|1|7.9e-93|344.0|phu:Phum_PHUM475870|acyl-CoA dehydrogenase [EC:1.3.8.7]"]
["JAR86700.1",7.425008167,null,"GO:0006085//acetyl-CoA biosynthetic process;GO:0006629//lipid metabolic process;GO:0006101//citrate metabolic process","GO:0003878//ATP citrate synthase activity;GO:0048037//cofactor binding;GO:0046872//metal ion binding;GO:0005524//ATP binding","GO:0005737//cytoplasm","Hs4501865",327.8,{"v":2.4e-89,"d":"2.40E-89"},"KOG1254","ATP-citrate lyase",null,"C","Energy production and conversion","METABOLISM","K01648|1|3.1e-92|342.8|obi:106879485|ATP citrate (pro-S)-lyase [EC:2.3.3.8]"]
["JAR86748.1",9.001955763,null,"GO:0050890//cognition;GO:0018279//protein N-linked glycosylation via asparagine","GO:0015095//magnesium ion transmembrane transporter activity","GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0008250//oligosaccharyltransferase complex","Hs6996934",417.9,{"v":1.5e-116,"d":"1.50E-116"},"KOG2603","Oligosaccharyltransferase, gamma subunit",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K12669|1|2.3e-120|436.0|acs:100566941|oligosaccharyltransferase complex subunit gamma"]
["JAR86763.1",null,null,"GO:0015031//protein transport;GO:0007264//small GTPase mediated signal transduction","GO:0005093//Rab GDP-dissociation inhibitor activity;GO:0005096//GTPase activator activity;GO:0016740//transferase activity","GO:0005737//cytoplasm",7297522,467.2,{"v":2e-131,"d":"2.00E-131"},"KOG1439","RAB proteins geranylgeranyltransferase component A (RAB escort protein)",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K17255|1|2.8e-152|542.0|isc:IscW_ISCW017892|Rab GDP dissociation inhibitor"]
["JAR86838.1",9.018718674,{"$nulls":3},"GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane",7296921,221.5,{"v":1.6e-57,"d":"1.60E-57"},"KOG1792","Reticulon",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K20721|1|2.3e-64|249.6|nvl:108559413|reticulon-1!K00688|2|8.2e-62|241.1|zne:110834544|glycogen phosphorylase [EC:2.4.1.1]"]
["JAR86886.1",9.634125699,null,"GO:0006811//ion transport",null,"GO:0005921//gap junction;GO:0016021//integral component of membrane;GO:0005886//plasma membrane",{"$nulls":9},"K22037|1|1.8e-149|532.7|isc:IscW_ISCW013694|innexin"]
["JAW05052.1",8.630498669,null,"GO:0006479//protein methylation;GO:0006355//regulation of transcription, DNA-templated","GO:0008469//histone-arginine N-methyltransferase activity;GO:0035242//protein-arginine omega-N asymmetric methyltransferase activity;GO:0008168//methyltransferase activity","GO:0005829//cytosol",7299364,333.2,{"v":3.1e-91,"d":"3.10E-91"},"KOG1499","Protein arginine N-methyltransferase PRMT1 and related enzymes",null,"OKT","Posttranslational modification, protein turnover, chaperones;Transcription;Signal transduction mechanisms","CELLULAR PROCESSES AND SIGNALING;INFORMATION STORAGE AND PROCESSING;CELLULAR PROCESSES AND SIGNALING","K11434|1|3.0e-113|411.8|isc:IscW_ISCW023973|type I protein arginine methyltransferase [EC:2.1.1.319]"]
["JAR86939.1",9.422676456,null,"GO:0042273//ribosomal large subunit biogenesis;GO:0006412//translation","GO:0003735//structural constituent of ribosome;GO:0003723//RNA binding","GO:0005840//ribosome;GO:0022625//cytosolic large ribosomal subunit","Hs16753225",140.6,{"v":2.2e-33,"d":"2.20E-33"},"KOG3421","60S ribosomal protein L14",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K02875|1|2.9e-57|225.3|isc:IscW_ISCW000979|large subunit ribosomal protein L14e"]
["JAR87266.1",null,null,"GO:0006574//valine catabolic process","GO:0003860//3-hydroxyisobutyryl-CoA hydrolase activity;GO:0016829//lyase activity","GO:0005739//mitochondrion",7300009,188.7,{"v":9.9e-48,"d":"9.90E-48"},"KOG1684","Enoyl-CoA hydratase",null,"I","Lipid transport and metabolism","METABOLISM","K05605|1|4.2e-86|321.6|isc:IscW_ISCW010016|3-hydroxyisobutyryl-CoA hydrolase [EC:3.1.2.4]"]
["JAR87301.1",8.498505851,null,"GO:0051603//proteolysis involved in cellular protein catabolic process","GO:0004298//threonine-type endopeptidase activity","GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005839//proteasome core complex",7303698,333.2,{"v":4.1e-91,"d":"4.10E-91"},"KOG0175","20S proteasome, regulatory subunit beta type PSMB5/PSMB8/PRE2",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K02737|1|1.8e-113|412.9|isc:IscW_ISCW005987|20S proteasome subunit beta 5 [EC:3.4.25.1]"]
["XP_064474980.1",7.885496458,{"$nulls":3},"GO:0016021//integral component of membrane",7303222,146,{"v":5.5e-35,"d":"5.50E-35"},"KOG1725","Protein involved in membrane traffic (YOP1/TB2/DP1/HVA22 family)",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K17279|1|6.7e-52|207.6|isc:IscW_ISCW010157|receptor expression-enhancing protein 5/6"]
["JAR87457.1",8.93120288,null,"GO:0006096//glycolytic process","GO:0000287//magnesium ion binding;GO:0004634//phosphopyruvate hydratase activity","GO:0000015//phosphopyruvate hydratase complex",7296048,448.4,{"v":9.1e-126,"d":"9.10E-126"},"KOG2670","Enolase",null,"G","Carbohydrate transport and metabolism","METABOLISM","K01689|1|7.7e-128|460.7|aga:AgaP_AGAP007827|enolase [EC:4.2.1.11]"]
["JAR87540.1",null,null,"GO:0018279//protein N-linked glycosylation via asparagine","GO:0016757//transferase activity, transferring glycosyl groups","GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","Hs20070197",554.7,{"v":1.3e-157,"d":"1.30E-157"},"KOG2754","Oligosaccharyltransferase, beta subunit",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K12670|1|5.3e-199|697.6|isc:IscW_ISCW017658|oligosaccharyltransferase complex subunit beta"]
["JAT78682.1",null,null,"GO:0042493//response to drug;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006616//SRP-dependent cotranslational protein targeting to membrane, translocation","GO:0005047//signal recognition particle binding;GO:0008312//7S RNA binding;GO:0043022//ribosome binding;GO:0030911//TPR domain binding","GO:0005786//signal recognition particle, endoplasmic reticulum targeting;GO:0005783//endoplasmic reticulum","Hs5902124",231.5,{"v":1.9e-60,"d":"1.90E-60"},"KOG2376","Signal recognition particle, subunit Srp72",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K03108|1|1.1e-90|337.4|isc:IscW_ISCW017299|signal recognition particle subunit SRP72"]
["JAT78904.1",{"$nulls":3},"GO:0004190//aspartic-type endopeptidase activity","GO:0030660//Golgi-associated vesicle membrane;GO:0016021//integral component of membrane;GO:0005765//lysosomal membrane;GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane;GO:0071458//integral component of cytoplasmic side of endoplasmic reticulum membrane","Hs22063651",291.2,{"v":1.5e-78,"d":"1.50E-78"},"KOG2443","Uncharacterized conserved protein",null,"S","Function unknown","POORLY CHARACTERIZED","K09595|1|3.6e-91|338.6|isc:IscW_ISCW006186|minor histocompatibility antigen H13 [EC:3.4.23.-]"]
["JAT78943.1",null,9.358009321,"GO:0006099//tricarboxylic acid cycle","GO:0004149//dihydrolipoyllysine-residue succinyltransferase activity","GO:0045252//oxoglutarate dehydrogenase complex","Hs19923748",212.6,{"v":5e-55,"d":"5.00E-55"},"KOG0559","Dihydrolipoamide succinyltransferase (2-oxoglutarate dehydrogenase, E2 subunit)",null,"C","Energy production and conversion","METABOLISM","K00658|1|2.4e-68|262.3|isc:IscW_ISCW008731|2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]"]
["JAT79030.1",9.016714536,null,"GO:0015986//ATP synthesis coupled proton transport","GO:0046933//proton-transporting ATP synthase activity, rotational mechanism",null,7299984,157.1,{"v":2.5e-38,"d":"2.50E-38"},"KOG1662","Mitochondrial F1F0-ATP synthase, subunit OSCP/ATP5",null,"C","Energy production and conversion","METABOLISM","K02137|1|5.0e-50|201.4|isc:IscW_ISCW021200|F-type H+-transporting ATPase subunit O"]
["JAT79126.1",9.228481897,null,null,"GO:0003723//RNA binding","GO:0019013//viral nucleocapsid;GO:0030529//intracellular ribonucleoprotein complex","Hs22042102",239.6,{"v":7.7e-63,"d":"7.70E-63"},"KOG0118","FOG: RRM domain",null,"R","General function prediction only","POORLY CHARACTERIZED","K03102|1|5.6e-85|318.5|lak:106158785|squid"]
["JAT79219.1",{"$nulls":4},"GO:0016021//integral component of membrane","Hs20536571",77.4,{"v":2.4e-14,"d":"2.40E-14"},"KOG4475","FOG: Immunoglobin and related proteins",null,"RP","General function prediction only;Inorganic ion transport and metabolism","POORLY CHARACTERIZED;METABOLISM","K22653|1|5.0e-15|85.1|lak:106160775|neuroplastin!K17341|2|8.4e-15|84.3|pdam:113683254|hemicentin"]
["JAW04060.1",null,8.791747724,null,"GO:0005524//ATP binding","GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0042645//mitochondrial nucleoid","Hs8922609",184.5,{"v":9.6e-47,"d":"9.60E-47"},"KOG0742","AAA+-type ATPase",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K17681|1|3.1e-48|194.9|zne:110830602|ATPase family AAA domain-containing protein 3A/B"]
["JAV98652.1",{"$nulls":3},"GO:0004177//aminopeptidase activity;GO:0008270//zinc ion binding;GO:0008237//metallopeptidase activity",null,7292091,951.4,{"v":1.1e-276,"d":"1.10E-276"},"KOG1046","Puromycin-sensitive aminopeptidase and related aminopeptidases",null,"EO","Amino acid transport and metabolism;Posttranslational modification, protein turnover, chaperones","METABOLISM;CELLULAR PROCESSES AND SIGNALING","K08776|1|7.7e-286|987.3|zne:110833944|puromycin-sensitive aminopeptidase [EC:3.4.11.-]"]
["JAV98657.1",8.555707184,{"$nulls":3},"GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","Hs13236516",319.7,{"v":4.4e-87,"d":"4.40E-87"},"KOG0858","Predicted membrane protein",null,"S","Function unknown","POORLY CHARACTERIZED","K11519|1|1.3e-102|376.7|zne:110831501|Derlin-1"]
["JAV98666.1",{"$nulls":3},"GO:0004671//protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity","GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","Hs6912430",289.3,{"v":7.3e-78,"d":"7.30E-78"},"KOG2628","Farnesyl cysteine-carboxyl methyltransferase",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K00587|1|8.3e-85|317.8|myi:110462725|protein-S-isoprenylcysteine O-methyltransferase [EC:2.1.1.100]"]
["JAV98671.1",8.252979864,null,null,"GO:0004721//phosphoprotein phosphatase activity;GO:0045296//cadherin binding;GO:0003723//RNA binding","GO:0005635//nuclear envelope;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005789//endoplasmic reticulum membrane;GO:0042645//mitochondrial nucleoid;GO:0031090//organelle membrane","CE28340",145.2,{"v":2e-34,"d":"2.00E-34"},"KOG0473","Leucine-rich repeat protein",null,"S","Function unknown","POORLY CHARACTERIZED","K19613|1|1.7e-12|77.8|bfo:BRAFLDRAFT_214464|leucine-rich repeat protein SHOC2"]
["JAV98706.1",8.598216941,null,"GO:0006749//glutathione metabolic process","GO:0004364//glutathione transferase activity","GO:0005737//cytoplasm",7299601,117.5,{"v":2e-26,"d":"2.00E-26"},"KOG0867","Glutathione S-transferase",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K00799|1|6.0e-47|191.0|isc:IscW_ISCW005805|glutathione S-transferase [EC:2.5.1.18]"]
["JAV98712.1",10.03674114,null,"GO:0051603//proteolysis involved in cellular protein catabolic process","GO:0004197//cysteine-type endopeptidase activity;GO:0008234//cysteine-type peptidase activity","GO:0005764//lysosome;GO:0005615//extracellular space","Hs4503155",369.8,{"v":4.9e-102,"d":"4.90E-102"},"KOG1543","Cysteine proteinase Cathepsin L",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K01365|1|1.7e-113|413.3|crg:105331752|cathepsin L [EC:3.4.22.15]"]
["JAV98724.1",null,null,"GO:0006814//sodium ion transport;GO:1904659//glucose transmembrane transport;GO:0055085//transmembrane transport","GO:0015293//symporter activity;GO:0005215//transporter activity;GO:0005412//glucose:sodium symporter activity","GO:0016021//integral component of membrane;GO:0005887//integral component of plasma membrane","Hs4507033",659.1,{"v":8.6e-189,"d":"8.60E-189"},"KOG2349","Na+:iodide/myo-inositol/multivitamin symporters",null,"P","Inorganic ion transport and metabolism","METABOLISM","K14389|1|4.1e-279|964.5|isc:IscW_ISCW012232|solute carrier family 5 (sodium/glucose cotransporter), member 9!K14382|3|5.1e-221|771.5|fcd:110862014|solute carrier family 5 (sodium/glucose cotransporter), member 2!K14158|5|3.9e-213|745.3|dpx:DAPPUDRAFT_215063|solute carrier family 5 (sodium/glucose cotransporter), member 1"]
["JAW00994.1",8.784432676,null,"GO:0043087//regulation of GTPase activity;GO:0007165//signal transduction",null,null,"Hs4506787",275.8,{"v":9.8e-74,"d":"9.80E-74"},"KOG2128","Ras GTPase-activating protein family - IQGAP",null,"T","Signal transduction mechanisms","CELLULAR PROCESSES AND SIGNALING","K16848|1|1.8e-123|446.4|isc:IscW_ISCW009822|Ras GTPase-activating-like protein IQGAP1"]
["JAW02394.1",9.202426067,null,"GO:0007052//mitotic spindle organization;GO:0007017//microtubule-based process",null,"GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005869//dynactin complex","Hs22059723",194.9,{"v":2.5e-49,"d":"2.50E-49"},"KOG3958","Putative dynamitin",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K10424|1|2.6e-65|253.4|isc:IscW_ISCW005007|dynactin 2"]
["JAV98855.1",{"$nulls":5},7296831,1265.4,0,"KOG2171","Karyopherin (importin) beta 3",null,"YU","Nuclear structure;Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING;CELLULAR PROCESSES AND SIGNALING","K20222|1|0.0e+00|1429.1|zne:110831990|importin-5"]
["JAW00866.1",null,null,"GO:0050772//positive regulation of axonogenesis;GO:0007162//negative regulation of cell adhesion;GO:0008360//regulation of cell shape;GO:0043087//regulation of GTPase activity","GO:0017154//semaphorin receptor activity","GO:0016021//integral component of membrane","Hs20536267",578.9,{"v":9.4e-165,"d":"9.40E-165"},"KOG3610","Plexins (functional semaphorin receptors)",null,"T","Signal transduction mechanisms","CELLULAR PROCESSES AND SIGNALING","K06820|1|0.0e+00|1085.1|isc:IscW_ISCW021345|plexin A"]
["XP_064488656.1",null,9.166706087,null,"GO:0003995//acyl-CoA dehydrogenase activity;GO:0050660//flavin adenine dinucleotide binding",null,"Hs21361497",562,{"v":1.3e-159,"d":"1.30E-159"},"KOG0137","Very-long-chain acyl-CoA dehydrogenase",null,"I","Lipid transport and metabolism","METABOLISM","K15980|1|3.5e-192|675.6|zne:110830236|acyl-CoA dehydrogenase family member 9 [EC:1.3.99.-]"]
["JAV98941.1",9.086412685,null,"GO:0016485//protein processing",null,"GO:0016021//integral component of membrane","Hs16165796",328.9,{"v":2e-89,"d":"2.00E-89"},"KOG2657","Transmembrane glycoprotein nicastrin",null,"TO","Signal transduction mechanisms;Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING;CELLULAR PROCESSES AND SIGNALING","K06171|1|4.1e-130|469.5|myi:110449068|nicastrin"]
["JAV98990.1",null,null,"GO:0000045//autophagosome assembly","GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0080025//phosphatidylinositol-3,5-bisphosphate binding","GO:0000407//phagophore assembly site","Hs7661580",546.6,{"v":4e-155,"d":"4.00E-155"},"KOG2110","Uncharacterized conserved protein, contains WD40 repeats",null,"S","Function unknown","POORLY CHARACTERIZED","K17908|1|1.5e-165|586.6|pcf:106784433|autophagy-related protein 18"]
["JAV98993.1",7.928593102,null,"GO:0006446//regulation of translational initiation;GO:0001731//formation of translation preinitiation complex","GO:0003743//translation initiation factor activity","GO:0005852//eukaryotic translation initiation factor 3 complex;GO:0016282//eukaryotic 43S preinitiation complex;GO:0033290//eukaryotic 48S preinitiation complex","Hs4503517",211.8,{"v":9.8e-55,"d":"9.80E-55"},"KOG0122","Translation initiation factor 3, subunit g (eIF-3g)",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K03248|1|9.7e-90|333.6|isc:IscW_ISCW000203|translation initiation factor 3 subunit G"]
["JAW06629.1",8.944070814,null,null,"GO:0047560//3-dehydrosphinganine reductase activity;GO:0016491//oxidoreductase activity","GO:0016021//integral component of membrane","Hs4503817",96.7,{"v":4e-20,"d":"4.00E-20"},"KOG1210","Predicted 3-ketosphinganine reductase",null,"Q","Secondary metabolites biosynthesis, transport and catabolism","METABOLISM","K04708|1|5.2e-23|111.7|isc:IscW_ISCW009465|3-dehydrosphinganine reductase [EC:1.1.1.102]"]
["JAV99000.1",9.353026373,{"$nulls":4},"Hs4758762",689.9,{"v":3e-198,"d":"3.00E-198"},"KOG0555","Asparaginyl-tRNA synthetase",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K01893|1|9.1e-206|720.3|epa:110237003|asparaginyl-tRNA synthetase [EC:6.1.1.22]"]
["JAV99026.1",9.227513418,null,"GO:0006435//threonyl-tRNA aminoacylation","GO:0004829//threonine-tRNA ligase activity;GO:0005524//ATP binding","GO:0005737//cytoplasm",7297921,1069.3,"2.8e-312","KOG1637","Threonyl-tRNA synthetase",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K01868|1|0.0e+00|1130.5|nvl:108565907|threonyl-tRNA synthetase [EC:6.1.1.3]"]
["JAV99032.1",null,8.964766888,null,"GO:0004792//thiosulfate sulfurtransferase activity",null,"Hs17438220",72.4,{"v":9.1e-13,"d":"9.10E-13"},"KOG1530","Rhodanese-related sulfurtransferase",null,"P","Inorganic ion transport and metabolism","METABOLISM","K01013|1|8.7e-19|97.8|cmk:103183481|thiosulfate:glutathione sulfurtransferase [EC:2.8.1.-]!K06089|2|1.6e-17|93.6|asn:102383480|junctional adhesion molecule 1"]
["JAV99074.1",null,null,"GO:0046513//ceramide biosynthetic process;GO:0006355//regulation of transcription, DNA-templated","GO:0043565//sequence-specific DNA binding;GO:0003677//DNA binding;GO:0050291//sphingosine N-acyltransferase activity","GO:0005783//endoplasmic reticulum;GO:0005634//nucleus;GO:0016021//integral component of membrane","Hs13375717",284.3,{"v":3e-76,"d":"3.00E-76"},"KOG1607","Protein transporter of the TRAM (translocating chain-associating membrane) superfamily",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K04710|1|9.7e-187|656.8|isc:IscW_ISCW005009|ceramide synthetase [EC:2.3.1.24]"]
["JAV99121.1",10.07833799,null,"GO:0006886//intracellular protein transport;GO:0016192//vesicle-mediated transport","GO:0008565//protein transporter activity","GO:0030131//clathrin adaptor complex",7293642,1374.8,0,"KOG1061","Vesicle coat complex AP-1/AP-2/AP-4, beta subunit",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K12392|1|0.0e+00|1614.4|isc:IscW_ISCW011108|AP-1 complex subunit beta-1"]
["JAV99125.1",9.681903789,null,null,"GO:0008168//methyltransferase activity;GO:0008112//nicotinamide N-methyltransferase activity;GO:0102707//S-adenosyl-L-methionine:beta-alanine N-methyltransferase activity;GO:0030748//amine N-methyltransferase activity;GO:0004603//phenylethanolamine N-methyltransferase activity",{"$nulls":10},"K00541|1|6.8e-46|188.3|isc:IscW_ISCW019697|nicotinamide N-methyltransferase [EC:2.1.1.1]"]
["JAV99176.1",9.862457278,null,"GO:0006090//pyruvate metabolic process","GO:0004742//dihydrolipoyllysine-residue acetyltransferase activity","GO:0005759//mitochondrial matrix;GO:0045254//pyruvate dehydrogenase complex","CE09597",505.8,{"v":8.6e-143,"d":"8.60E-143"},"KOG0557","Dihydrolipoamide acetyltransferase",null,"C","Energy production and conversion","METABOLISM","K00627|1|6.5e-178|627.9|isc:IscW_ISCW013308|pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase) [EC:2.3.1.12]"]
["JAW06144.1",null,8.008834982,null,"GO:0004402//histone acetyltransferase activity",null,"Hs8923956",226.9,{"v":1e-58,"d":"1.00E-58"},"KOG1334","WD40 repeat protein",null,"R","General function prediction only","POORLY CHARACTERIZED","K11795|1|1.3e-173|614.0|isc:IscW_ISCW020123|nuclear receptor interaction protein"]
["JAV99248.1",null,null,"GO:0006508//proteolysis","GO:0004198//calcium-dependent cysteine-type endopeptidase activity;GO:0005509//calcium ion binding","GO:0005737//cytoplasm",7294858,359.8,{"v":5.9e-99,"d":"5.90E-99"},"KOG0045","Cytosolic Ca2+-dependent cysteine protease (calpain), large subunit (EF-Hand protein superfamily)",null,"OT","Posttranslational modification, protein turnover, chaperones;Signal transduction mechanisms","CELLULAR PROCESSES AND SIGNALING;CELLULAR PROCESSES AND SIGNALING","K08585|1|7.0e-172|607.4|isc:IscW_ISCW012923|calpain, invertebrate [EC:3.4.22.-]"]
["JAV99255.1",9.700932343,null,null,"GO:0003723//RNA binding;GO:0008270//zinc ion binding",null,7295256,100.5,{"v":3.6e-21,"d":"3.60E-21"},"KOG0109","RNA-binding protein LARK, contains RRM and retroviral-type Zn-finger domains",null,"AR","RNA processing and modification;General function prediction only","INFORMATION STORAGE AND PROCESSING;POORLY CHARACTERIZED","K13187|1|1.7e-29|133.7|lak:106158859|RNA-binding protein 4!K14651|5|1.4e-23|114.0|dpa:109536409|transcription initiation factor TFIID subunit 15"]
["JAV99265.1",9.517596344,null,"GO:0006888//ER to Golgi vesicle-mediated transport","GO:0005537//mannose binding","GO:0005737//cytoplasm;GO:0016021//integral component of membrane",7295074,503.1,{"v":5.6e-142,"d":"5.60E-142"},"KOG3838","Mannose lectin ERGIC-53, involved in glycoprotein traffic",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K10080|1|1.1e-190|670.2|isc:IscW_ISCW016179|lectin, mannose-binding 1"]
["JAV99266.1",null,null,"GO:0006897//endocytosis;GO:0016050//vesicle organization;GO:0042147//retrograde transport, endosome to Golgi;GO:0006886//intracellular protein transport;GO:0034498//early endosome to Golgi transport","GO:0035091//phosphatidylinositol binding","GO:0005829//cytosol;GO:0005622//intracellular;GO:0030904//retromer complex;GO:0019898//extrinsic component of membrane;GO:0010008//endosome membrane","Hs14725602",362.5,{"v":9.8e-100,"d":"9.80E-100"},"KOG2273","Membrane coat complex Retromer, subunit VPS5/SNX1, Sorting nexins, and related PX domain-containing proteins",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K17917|1|4.3e-135|485.3|isc:IscW_ISCW021592|sorting nexin-1/2"]
["JAV99272.1",10.17498995,null,"GO:0006749//glutathione metabolic process","GO:0004364//glutathione transferase activity","GO:0005737//cytoplasm",7299600,139,{"v":1.2e-32,"d":"1.20E-32"},"KOG0867","Glutathione S-transferase",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K00799|1|1.8e-55|220.3|isc:IscW_ISCW005805|glutathione S-transferase [EC:2.5.1.18]"]
["XP_064460731.1",null,null,"GO:0006635//fatty acid beta-oxidation;GO:0033539//fatty acid beta-oxidation using acyl-CoA dehydrogenase","GO:0050660//flavin adenine dinucleotide binding;GO:0003995//acyl-CoA dehydrogenase activity;GO:0003997//acyl-CoA oxidase activity;GO:0071949//FAD binding","GO:0005777//peroxisome","Hs4501871",681,{"v":2.1e-195,"d":"2.10E-195"},"KOG0135","Pristanoyl-CoA/acyl-CoA oxidase",null,"IQ","Lipid transport and metabolism;Secondary metabolites biosynthesis, transport and catabolism","METABOLISM;METABOLISM","K00232|1|0.0e+00|1193.7|isc:IscW_ISCW013214|acyl-CoA oxidase [EC:1.3.3.6]"]
["JAV99295.1",8.280870894,null,null,"GO:0004458//D-lactate dehydrogenase (cytochrome) activity;GO:0050660//flavin adenine dinucleotide binding;GO:0016614//oxidoreductase activity, acting on CH-OH group of donors",null,"CE23698_3",443.4,{"v":5.2e-124,"d":"5.20E-124"},"KOG1231","Proteins containing the FAD binding domain",null,"C","Energy production and conversion","METABOLISM","K00102|1|9.2e-193|677.2|isc:IscW_ISCW013290|D-lactate dehydrogenase (cytochrome) [EC:1.1.2.4]"]
["JAV99323.1",{"$nulls":3},"GO:0003743//translation initiation factor activity",null,"Hs10092601",649.4,{"v":1.1e-185,"d":"1.10E-185"},"KOG0401","Translation initiation factor 4F, ribosome/mRNA-bridging subunit (eIF-4G)",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K03260|1|1.4e-247|860.5|isc:IscW_ISCW008595|translation initiation factor 4G"]
["JAV99357.1",9.161091873,null,"GO:0015031//protein transport",null,"GO:0016021//integral component of membrane","Hs16445416",313.5,{"v":4.5e-85,"d":"4.50E-85"},"KOG3088","Secretory carrier membrane protein",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K19995|1|3.1e-158|562.0|isc:IscW_ISCW004504|secretory carrier-associated membrane protein"]
["JAV99367.1",9.006707516,null,null,"GO:0003746//translation elongation factor activity","GO:0005853//eukaryotic translation elongation factor 1 complex","Hs4503477",271.9,{"v":9e-73,"d":"9.00E-73"},"KOG1668","Elongation factor 1 beta/delta chain",null,"K","Transcription","INFORMATION STORAGE AND PROCESSING","K03232|1|3.9e-87|325.1|isc:IscW_ISCW004620|elongation factor 1-beta"]
["JAV99411.1",8.314229356,{"$nulls":4},7301749,656,{"v":4.2e-188,"d":"4.20E-188"},"KOG2189","Vacuolar H+-ATPase V0 sector, subunit a",null,"C","Energy production and conversion","METABOLISM","K02154|1|4.0e-194|681.4|bter:100644609|V-type H+-transporting ATPase subunit a"]
["JAW06483.1",null,null,"GO:0008611//ether lipid biosynthetic process","GO:0008609//alkylglycerone-phosphate synthase activity;GO:0050660//flavin adenine dinucleotide binding;GO:0016614//oxidoreductase activity, acting on CH-OH group of donors","GO:0005777//peroxisome","Hs4501993",264.6,{"v":1.5e-70,"d":"1.50E-70"},"KOG1233","Alkyl-dihydroxyacetonephosphate synthase",null,"R","General function prediction only","POORLY CHARACTERIZED","K00803|1|2.1e-83|312.8|isc:IscW_ISCW016253|alkyldihydroxyacetonephosphate synthase [EC:2.5.1.26]"]
["JAV99457.1",8.991667104,null,"GO:0032922//circadian regulation of gene expression;GO:0060028//convergent extension involved in axis elongation;GO:0000086//G2/M transition of mitotic cell cycle;GO:0006470//protein dephosphorylation;GO:0030155//regulation of cell adhesion;GO:0001889//liver development;GO:0007049//cell cycle;GO:0005981//regulation of glycogen catabolic process;GO:0051301//cell division;GO:0042752//regulation of circadian rhythm;GO:0005977//glycogen metabolic process;GO:0005979//regulation of glycogen biosynthetic process;GO:0019433//triglyceride catabolic process;GO:0043153//entrainment of circadian clock by photoperiod","GO:0016791//phosphatase activity;GO:0046872//metal ion binding;GO:0050115//myosin-light-chain-phosphatase activity;GO:0017018//myosin phosphatase activity;GO:0030145//manganese ion binding;GO:0019901//protein kinase binding;GO:0004722//protein serine/threonine phosphatase activity;GO:0004721//phosphoprotein phosphatase activity;GO:0046982//protein heterodimerization activity","GO:0000784//nuclear chromosome, telomeric region;GO:0005925//focal adhesion;GO:0072357//PTW/PP1 phosphatase complex;GO:0005737//cytoplasm;GO:0070062//extracellular exosome;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0000164//protein phosphatase type 1 complex;GO:0005654//nucleoplasm;GO:0098723//skeletal muscle myofibril;GO:0042587//glycogen granule;GO:0005829//cytosol","Hs4506005",657.9,{"v":8.8e-189,"d":"8.80E-189"},"KOG0374","Serine/threonine specific protein phosphatase PP1, catalytic subunit",null,"TR","Signal transduction mechanisms;General function prediction only","CELLULAR PROCESSES AND SIGNALING;POORLY CHARACTERIZED","K06269|1|4.1e-189|664.5|tut:107359585|serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"]
["JAW00792.1",null,null,"GO:0001707//mesoderm formation;GO:0008283//cell proliferation;GO:0000305//response to oxygen radical;GO:0007369//gastrulation;GO:0045454//cell redox homeostasis","GO:0050660//flavin adenine dinucleotide binding;GO:0009055//electron transfer activity;GO:0004791//thioredoxin-disulfide reductase activity","GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0001650//fibrillar center;GO:0005829//cytosol","Hs4507747",465.7,{"v":6.6e-131,"d":"6.60E-131"},"KOG4716","Thioredoxin reductase",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K22182|1|1.9e-133|479.6|cfr:102518987|thioredoxin reductase (NADPH) [EC:1.8.1.9]"]
["JAV99484.1",null,null,"GO:0006430//lysyl-tRNA aminoacylation","GO:0004824//lysine-tRNA ligase activity;GO:0005524//ATP binding;GO:0003676//nucleic acid binding","GO:0005737//cytoplasm",7291073,828.2,{"v":9.4e-240,"d":"9.40E-240"},"KOG1885","Lysyl-tRNA synthetase (class II)",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K04567|1|3.6e-271|937.9|isc:IscW_ISCW018044|lysyl-tRNA synthetase, class II [EC:6.1.1.6]"]
["JAV99506.1",null,null,"GO:0020027//hemoglobin metabolic process;GO:0055072//iron ion homeostasis;GO:0045454//cell redox homeostasis","GO:0046872//metal ion binding;GO:0015035//protein disulfide oxidoreductase activity;GO:0051536//iron-sulfur cluster binding;GO:0009055//electron transfer activity","GO:0005829//cytosol;GO:0005623//cell","Hs5730104",243.8,{"v":4e-64,"d":"4.00E-64"},"KOG0911","Glutaredoxin-related protein",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K15216|1|3.5e-31|139.8|tsp:Tsp_09255|RNA polymerase I-specific transcription initiation factor RRN3!K07390|2|1.7e-22|110.9|phu:Phum_PHUM603470|monothiol glutaredoxin"]
["JAV99525.1",{"$nulls":3},"GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0003743//translation initiation factor activity",null,"Hs15451892",918.7,{"v":6.6e-267,"d":"6.60E-267"},"KOG1144","Translation initiation factor 5B (eIF-5B)",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K03243|1|1.7e-302|1042.3|hst:105182586|translation initiation factor 5B"]
["JAV99543.1",10.44965565,null,null,"GO:0032440//2-alkenal reductase [NAD(P)] activity;GO:0005198//structural molecule activity","GO:0005882//intermediate filament",7296991,458.8,{"v":1.5e-128,"d":"1.50E-128"},"KOG0977","Nuclear envelope protein lamin, intermediate filament superfamily",null,"DY","Cell cycle control, cell division, chromosome partitioning;Nuclear structure","CELLULAR PROCESSES AND SIGNALING;CELLULAR PROCESSES AND SIGNALING","K07611|1|4.9e-220|768.1|isc:IscW_ISCW000339|lamin B"]
["JAV99550.1",8.841293088,null,"GO:0006457//protein folding;GO:0045454//cell redox homeostasis;GO:0034976//response to endoplasmic reticulum stress","GO:0016853//isomerase activity;GO:0003756//protein disulfide isomerase activity","GO:0005623//cell;GO:0005783//endoplasmic reticulum",7298052,595.5,{"v":1.1e-169,"d":"1.10E-169"},"KOG0191","Thioredoxin/protein disulfide isomerase",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K09583|1|1.1e-222|776.9|zne:110840378|protein disulfide-isomerase A5 [EC:5.3.4.1]!K01829|4|1.4e-212|743.4|aga:AgaP_AGAP010217|protein disulfide-isomerase [EC:5.3.4.1]"]
["JAV99621.1",9.054831755,null,"GO:0006890//retrograde vesicle-mediated transport, Golgi to ER",null,"GO:0016021//integral component of membrane",7301302,254.6,{"v":1.4e-67,"d":"1.40E-67"},"KOG1688","Golgi proteins involved in ER retention (RER)",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K04624|1|1.2e-66|256.9|tng:GSTEN00022528G001|taste receptor type 1 member 1"]
["JAV99659.1",9.828550278,null,"GO:0007030//Golgi organization",null,"GO:0005794//Golgi apparatus","Hs20127539",344.7,{"v":1.5e-94,"d":"1.50E-94"},"KOG3834","Golgi reassembly stacking protein GRASP65, contains PDZ domain",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING"]
["JAV99666.1",{"$nulls":3},"GO:0008565//protein transporter activity","GO:0016021//integral component of membrane","Hs4507525",273.9,{"v":3.5e-73,"d":"3.50E-73"},"KOG2927","Membrane component of ER protein translocation complex",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K12275|1|1.1e-114|417.2|isc:IscW_ISCW008339|translocation protein SEC62"]
["JAV99677.1",null,8.367431343,"GO:0055129//L-proline biosynthetic process;GO:0006561//proline biosynthetic process","GO:0004735//pyrroline-5-carboxylate reductase activity",null,"CE03511",266.9,{"v":3.6e-71,"d":"3.60E-71"},"KOG3124","Pyrroline-5-carboxylate reductase",null,"E","Amino acid transport and metabolism","METABOLISM","K00286|1|1.6e-90|336.7|isc:IscW_ISCW020302|pyrroline-5-carboxylate reductase [EC:1.5.1.2]"]
["JAV99700.1",8.406921725,null,"GO:0010468//regulation of gene expression","GO:0004707//MAP kinase activity;GO:0005524//ATP binding","GO:0005737//cytoplasm;GO:0005634//nucleus","Hs20986512",539.7,{"v":3.8e-153,"d":"3.80E-153"},"KOG0660","Mitogen-activated protein kinase",null,"T","Signal transduction mechanisms","CELLULAR PROCESSES AND SIGNALING","K04441|1|1.5e-192|676.0|isc:IscW_ISCW021966|p38 MAP kinase [EC:2.7.11.24]"]
["JAV99719.1",9.126488027,null,"GO:0001678//cellular glucose homeostasis;GO:0006096//glycolytic process","GO:0008865//fructokinase activity;GO:0004396//hexokinase activity;GO:0004340//glucokinase activity;GO:0019158//mannokinase activity;GO:0005524//ATP binding;GO:0005536//glucose binding","GO:0005829//cytosol;GO:0005623//cell",7291070,406,{"v":9.2e-113,"d":"9.20E-113"},"KOG1369","Hexokinase",null,"G","Carbohydrate transport and metabolism","METABOLISM","K00844|1|1.3e-181|640.2|isc:IscW_ISCW012387|hexokinase [EC:2.7.1.1]"]
["JAV99765.1",null,null,"GO:0046854//phosphatidylinositol phosphorylation",null,null,"Hs5174399",332.4,{"v":8.4e-91,"d":"8.40E-91"},"KOG3099","Bisphosphate 3'-nucleotidase BPNT1/Inositol polyphosphate 1-phosphatase",null,"F","Nucleotide transport and metabolism","METABOLISM","K01082|1|7.8e-108|394.4|bfo:BRAFLDRAFT_285264|3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7]"]
["JAV99774.1",8.683142402,null,"GO:0006396//RNA processing",null,"GO:0016021//integral component of membrane","Hs7662673",216.5,{"v":5.7e-56,"d":"5.70E-56"},"KOG0547","Translocase of outer mitochondrial membrane complex, subunit TOM70/TOM72",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K17768|1|7.5e-96|354.4|isc:IscW_ISCW008890|mitochondrial import receptor subunit TOM70"]
["JAV99787.1",9.263326691,null,"GO:0006511//ubiquitin-dependent protein catabolic process","GO:0004298//threonine-type endopeptidase activity","GO:0005737//cytoplasm;GO:0019773//proteasome core complex, alpha-subunit complex;GO:0005634//nucleus","Hs14749945",379,{"v":6e-105,"d":"6.00E-105"},"KOG0182","20S proteasome, regulatory subunit alpha type PSMA6/SCL1",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K02730|1|1.5e-111|406.4|mdl:103568553|20S proteasome subunit alpha 1 [EC:3.4.25.1]"]
["JAV99804.1",{"$nulls":3},"GO:0033868//Goodpasture-antigen-binding protein kinase activity;GO:0120013//intermembrane lipid transfer activity","GO:0005737//cytoplasm","Hs7705684_2",119.4,{"v":8.2e-27,"d":"8.20E-27"},"KOG3221","Glycolipid transfer protein",null,"G","Carbohydrate transport and metabolism","METABOLISM","K08051|1|4.0e-53|212.2|isc:IscW_ISCW008909|pleckstrin homology domain containing family A member 8"]
["JAV99805.1",10.55077372,null,"GO:1900037//regulation of cellular response to hypoxia;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007005//mitochondrion organization","GO:0043565//sequence-specific DNA binding;GO:0008134//transcription factor binding","GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005654//nucleoplasm;GO:0005758//mitochondrial intermembrane space;GO:0005829//cytosol",7293321,156.4,{"v":4e-38,"d":"4.00E-38"},"KOG4090","Uncharacterized conserved protein",null,"S","Function unknown","POORLY CHARACTERIZED","K22758|1|5.7e-48|194.5|isc:IscW_ISCW015312|coiled-coil-helix-coiled-coil-helix domain-containing protein 2"]
["JAW01398.1",8.739073965,null,"GO:0009298//GDP-mannose biosynthetic process;GO:0009058//biosynthetic process","GO:0016779//nucleotidyltransferase activity;GO:0004475//mannose-1-phosphate guanylyltransferase activity;GO:0005525//GTP binding","GO:0005737//cytoplasm;GO:0070062//extracellular exosome;GO:0005739//mitochondrion","Hs11761619",154.5,{"v":1.2e-37,"d":"1.20E-37"},"KOG1322","GDP-mannose pyrophosphorylase/mannose-1-phosphate guanylyltransferase",null,"M","Cell wall/membrane/envelope biogenesis","CELLULAR PROCESSES AND SIGNALING","K00966|1|3.5e-40|168.3|isc:IscW_ISCW019597|mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]"]
["JAV99819.1",9.133210437,{"$nulls":4},"CE03664",343.6,{"v":4.3e-94,"d":"4.30E-94"},"KOG1482","Zn2+ transporter",null,"P","Inorganic ion transport and metabolism","METABOLISM","K14689|1|8.6e-114|414.5|tnl:113501686|solute carrier family 30 (zinc transporter), member 2"]
["JAV99827.1",null,null,"GO:0006412//translation","GO:0003735//structural constituent of ribosome","GO:0005840//ribosome","Hs4506699",130.6,{"v":1.2e-30,"d":"1.20E-30"},"KOG3486","40S ribosomal protein S21",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K02971|1|3.4e-31|137.9|lak:106168729|small subunit ribosomal protein S21e"]
["JAV99836.1",9.996038046,null,"GO:0045047//protein targeting to ER;GO:0006465//signal peptide processing","GO:0008233//peptidase activity","GO:0005787//signal peptidase complex;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane","Hs22045875",97.4,{"v":1.4e-20,"d":"1.40E-20"},"KOG4112","Signal peptidase subunit",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K12946|1|5.9e-38|160.6|isc:IscW_ISCW019568|signal peptidase complex subunit 1 [EC:3.4.-.-]"]
["JAW00879.1",null,8.775280892,"GO:0006810//transport","GO:0008521//acetyl-CoA transmembrane transporter activity;GO:0015295//solute:proton symporter activity","GO:0016021//integral component of membrane;GO:0005887//integral component of plasma membrane","Hs4757708",292,{"v":1.1e-78,"d":"1.10E-78"},"KOG3574","Acetyl-CoA transporter",null,"P","Inorganic ion transport and metabolism","METABOLISM","K03372|1|1.2e-93|347.1|isc:IscW_ISCW023593|MFS transporter, PAT family, solute carrier family 33 (acetyl-CoA transportor), member 1 [EC:2.3.1.-]"]
["JAV99860.1",8.377120073,null,"GO:0071586//CAAX-box protein processing","GO:0004222//metalloendopeptidase activity","GO:0016021//integral component of membrane","Hs18379366",517.7,{"v":2.1e-146,"d":"2.10E-146"},"KOG2719","Metalloprotease",null,"R","General function prediction only","POORLY CHARACTERIZED","K06013|1|7.0e-153|544.7|lgi:LOTGIDRAFT_209825|STE24 endopeptidase [EC:3.4.24.84]"]
["JAW01659.1",null,null,"GO:0006432//phenylalanyl-tRNA aminoacylation","GO:0004826//phenylalanine-tRNA ligase activity;GO:0000287//magnesium ion binding;GO:0003723//RNA binding;GO:0005524//ATP binding","GO:0005737//cytoplasm;GO:0009328//phenylalanine-tRNA ligase complex;GO:0016021//integral component of membrane","CE20708",93.6,{"v":2.5e-19,"d":"2.50E-19"},"KOG2472","Phenylalanyl-tRNA synthetase beta subunit",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K01890|1|1.8e-20|102.8|isc:IscW_ISCW018574|phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]"]
["XP_064477276.1",null,null,"GO:0006914//autophagy",null,null,"Hs14210522",170.2,{"v":2.2e-42,"d":"2.20E-42"},"KOG1654","Microtubule-associated anchor protein involved in autophagy and membrane trafficking",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K10435|1|5.1e-42|174.5|csem:103386752|microtubule-associated protein 1 light chain"]
["JAV99875.1",9.023062482,null,"GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process","GO:0004298//threonine-type endopeptidase activity","GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0019774//proteasome core complex, beta-subunit complex",7299121,284.6,{"v":1.3e-76,"d":"1.30E-76"},"KOG0180","20S proteasome, regulatory subunit beta type PSMB3/PUP3",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K02735|1|8.2e-87|323.9|zne:110832135|20S proteasome subunit beta 3 [EC:3.4.25.1]"]
["JAV99934.1",9.729399782,null,null,"GO:0030060//L-malate dehydrogenase activity;GO:0016491//oxidoreductase activity"]
["JAV99956.1",8.567024774,null,null,"GO:0004316//3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity;GO:0102132//3-oxo-pimeloyl-[acp] methyl ester reductase activity;GO:0102131//3-oxo-glutaryl-[acp] methyl ester reductase activity;GO:0016491//oxidoreductase activity",null,7296705,271.6,{"v":1.4e-72,"d":"1.40E-72"},"KOG0725","Reductases with broad range of substrate specificities",null,"R","General function prediction only","POORLY CHARACTERIZED","K10956|1|5.9e-58|228.4|egl:EGR_00201|protein transport protein SEC61 subunit alpha!K10402|2|2.3e-38|163.3|dpte:113790734|kinesin family member 20!K11147|4|7.8e-34|148.3|clec:106663222|dehydrogenase/reductase SDR family member 4 [EC:1.1.-.-]"]
["XP_064461063.1",{"$nulls":5},"Hs16753203",550.8,{"v":2.7e-156,"d":"2.70E-156"},"KOG0010","Ubiquitin-like protein",null,"OR","Posttranslational modification, protein turnover, chaperones;General function prediction only","CELLULAR PROCESSES AND SIGNALING;POORLY CHARACTERIZED","K04523|1|8.1e-209|730.7|isc:IscW_ISCW006829|ubiquilin"]
["JAW00019.1",9.889347952,null,"GO:0045047//protein targeting to ER;GO:0006465//signal peptide processing","GO:0008233//peptidase activity","GO:0005787//signal peptidase complex;GO:0016021//integral component of membrane",7301130,252.7,{"v":4.7e-67,"d":"4.70E-67"},"KOG3372","Signal peptidase complex subunit",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K12948|1|7.7e-81|303.9|isc:IscW_ISCW016779|signal peptidase complex subunit 3 [EC:3.4.-.-]"]
["JAW00068.1",9.667894888,{"$nulls":4},"CE08028_2",122.5,{"v":2.6e-27,"d":"2.60E-27"},"KOG4475","FOG: Immunoglobin and related proteins",null,"RP","General function prediction only;Inorganic ion transport and metabolism","POORLY CHARACTERIZED;METABOLISM","K04574|1|4.4e-30|137.1|pss:102450392|neurofilament heavy polypeptide"]
["JAW01025.1",8.894095409,null,"GO:0030100//regulation of endocytosis","GO:0003924//GTPase activity;GO:0004767//sphingomyelin phosphodiesterase activity;GO:0005525//GTP binding","GO:0005768//endosome;GO:0005739//mitochondrion;GO:0032593//insulin-responsive compartment","Hs21361509",219.5,{"v":3.4e-57,"d":"3.40E-57"},"KOG0086","GTPase Rab4, small G protein superfamily",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K07880|1|1.0e-61|240.0|isc:IscW_ISCW020598|Ras-related protein Rab-4B"]
["JAW02938.1",10.43157566,null,null,"GO:0005125//cytokine activity","GO:0005576//extracellular region"]
["JAW00246.1",9.069586655,{"$nulls":4},"Hs17437061",72.8,{"v":1.1e-12,"d":"1.10E-12"},"KOG3751","Growth factor receptor-bound proteins (GRB7, GRB10, GRB14)",null,"T","Signal transduction mechanisms","CELLULAR PROCESSES AND SIGNALING","K02184|1|7.4e-17|92.0|ame:726681|formin 2"]
["JAW00320.1",null,null,"GO:0006426//glycyl-tRNA aminoacylation;GO:0070150//mitochondrial glycyl-tRNA aminoacylation","GO:0004820//glycine-tRNA ligase activity;GO:0005524//ATP binding","GO:0005737//cytoplasm;GO:0005739//mitochondrion","Hs6996010",100.1,{"v":1.6e-21,"d":"1.60E-21"},"KOG2298","Glycyl-tRNA synthetase and related class II tRNA synthetase",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K01880|1|6.6e-23|110.2|isc:IscW_ISCW014402|glycyl-tRNA synthetase [EC:6.1.1.14]"]
["JAW00326.1",9.762506866,null,null,"GO:0005319//lipid transporter activity;GO:0005509//calcium ion binding","GO:0016021//integral component of membrane","Hs4557803",95.9,{"v":7.2e-20,"d":"7.20E-20"},"KOG1933","Cholesterol transport protein (Niemann-Pick C disease protein)",null,"I","Lipid transport and metabolism","METABOLISM","K20371|1|3.3e-36|155.6|isc:IscW_ISCW020300|nucleobindin!K12385|2|3.9e-21|105.5|crg:105338347|Niemann-Pick C1 protein"]
["JAW00447.1",9.883408639,null,null,"GO:0005215//transporter activity","GO:0016021//integral component of membrane","Hs10835169",116.3,{"v":4.1e-26,"d":"4.10E-26"},"KOG1291","Mn2+ and Fe2+ transporters of the NRAMP family",null,"P","Inorganic ion transport and metabolism","METABOLISM","K21398|1|2.0e-28|129.4|tca:655866|natural resistance-associated macrophage protein 2"]
["JAW00472.1",null,null,"GO:0030203//glycosaminoglycan metabolic process","GO:0008449//N-acetylglucosamine-6-sulfatase activity","GO:0005764//lysosome","Hs4504061",104,{"v":1.8e-22,"d":"1.80E-22"},"KOG3731","Sulfatases",null,"G","Carbohydrate transport and metabolism","METABOLISM","K01137|1|5.6e-27|124.4|pbar:105426645|N-acetylglucosamine-6-sulfatase [EC:3.1.6.14]"]
["JAW00520.1",null,null,"GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination","GO:0016740//transferase activity;GO:0036459//thiol-dependent ubiquitinyl hydrolase activity","GO:0005634//nucleus","Hs4827050",217.6,{"v":2.5e-56,"d":"2.50E-56"},"KOG1872","Ubiquitin-specific protease",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K11843|1|1.0e-73|280.8|isc:IscW_ISCW019604|ubiquitin carboxyl-terminal hydrolase 14 [EC:3.4.19.12]"]
["JAW00714.1",null,9.795014134,"GO:0018107//peptidyl-threonine phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0034501//protein localization to kinetochore;GO:0030154//cell differentiation;GO:0044772//mitotic cell cycle phase transition;GO:0000226//microtubule cytoskeleton organization;GO:0007346//regulation of mitotic cell cycle;GO:0043066//negative regulation of apoptotic process;GO:0016572//histone phosphorylation;GO:0010468//regulation of gene expression;GO:0006281//DNA repair;GO:0030855//epithelial cell differentiation;GO:0010971//positive regulation of G2/M transition of mitotic cell cycle;GO:0051445//regulation of meiotic cell cycle;GO:0008283//cell proliferation;GO:1900182//positive regulation of protein localization to nucleus;GO:1905448//positive regulation of mitochondrial ATP synthesis coupled electron transport;GO:0007095//mitotic G2 DNA damage checkpoint","GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0008353//RNA polymerase II carboxy-terminal domain kinase activity;GO:0030544//Hsp70 protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0030332//cyclin binding;GO:0035173//histone kinase activity;GO:0003682//chromatin binding","GO:0000784//nuclear chromosome, telomeric region;GO:0005876//spindle microtubule;GO:0005737//cytoplasm;GO:0072686//mitotic spindle;GO:0070062//extracellular exosome;GO:0005813//centrosome;GO:0005634//nucleus;GO:0016020//membrane;GO:0097125//cyclin B1-CDK1 complex;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0030496//midbody","Hs4502709",246.9,{"v":2.4e-65,"d":"2.40E-65"},"KOG0594","Protein kinase PCTAIRE and related kinases",null,"R","General function prediction only","POORLY CHARACTERIZED","K02087|1|6.4e-66|254.2|crg:105346130|cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]"]
["JAW00733.1",null,null,"GO:0009072//aromatic amino acid family metabolic process;GO:0006559//L-phenylalanine catabolic process","GO:0004510//tryptophan 5-monooxygenase activity;GO:0004505//phenylalanine 4-monooxygenase activity;GO:0005506//iron ion binding",null,"Hs4557819",91.3,{"v":1.4e-18,"d":"1.40E-18"},"KOG3820","Aromatic amino acid hydroxylase",null,"E","Amino acid transport and metabolism","METABOLISM","K00500|1|3.6e-25|118.6|dpx:DAPPUDRAFT_220530|phenylalanine-4-hydroxylase [EC:1.14.16.1]"]
["JAW00744.1",7.836332579,null,"GO:0042273//ribosomal large subunit biogenesis;GO:0002181//cytoplasmic translation;GO:0006412//translation","GO:0003735//structural constituent of ribosome;GO:0003723//RNA binding","GO:0015934//large ribosomal subunit;GO:0022625//cytosolic large ribosomal subunit","Hs4506621",182.6,{"v":3.9e-46,"d":"3.90E-46"},"KOG3401","60S ribosomal protein L26",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K02898|1|7.8e-50|200.3|spu:585872|large subunit ribosomal protein L26e"]
["JAW00809.1",{"$nulls":5},"Hs13775188",112.8,{"v":1.6e-24,"d":"1.60E-24"},"KOG2039","Transcriptional coactivator p100",null,"K","Transcription","INFORMATION STORAGE AND PROCESSING","K18405|1|4.5e-35|153.3|nve:NEMVE_v1g245679|tudor domain-containing protein 1/4/6/7"]
["JAW00817.1",9.145842047,null,"GO:0006769//nicotinamide metabolic process;GO:0008152//metabolic process","GO:0008936//nicotinamidase activity;GO:0003824//catalytic activity;GO:0005509//calcium ion binding","GO:0005737//cytoplasm",7300541,219.2,{"v":1.1e-56,"d":"1.10E-56"},"KOG4003","Pyrazinamidase/nicotinamidase PNC1",null,"V","Defense mechanisms","CELLULAR PROCESSES AND SIGNALING","K03679|1|3.8e-65|252.7|bim:100747413|exosome complex component RRP4"]
["JAW00949.1",null,null,"GO:0006631//fatty acid metabolic process","GO:0003857//3-hydroxyacyl-CoA dehydrogenase activity;GO:0070403//NAD+ binding",null,"Hs4885387",88.2,{"v":7.3e-18,"d":"7.30E-18"},"KOG2304","3-hydroxyacyl-CoA dehydrogenase",null,"I","Lipid transport and metabolism","METABOLISM","K00022|1|4.8e-25|117.5|isc:IscW_ISCW014460|3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35]"]
["JAW00985.1",null,null,"GO:0006457//protein folding;GO:0043277//apoptotic cell clearance;GO:0045454//cell redox homeostasis;GO:0034976//response to endoplasmic reticulum stress","GO:0016853//isomerase activity;GO:0003756//protein disulfide isomerase activity","GO:0005623//cell;GO:0005783//endoplasmic reticulum","Hs13540604",161.4,{"v":2e-39,"d":"2.00E-39"},"KOG0191","Thioredoxin/protein disulfide isomerase",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K13984|1|2.1e-84|316.2|isc:IscW_ISCW004748|thioredoxin domain-containing protein 5"]
["JAW01014.1",8.117567524,{"$nulls":3},"GO:0016021//integral component of membrane",{"$nulls":9},"K20493|1|7.0e-18|95.5|zne:110833737|leucine-rich repeat-containing protein 16"]
["JAW01039.1",8.939925751,null,"GO:0051694//pointed-end actin filament capping","GO:0005523//tropomyosin binding",null,7301961,129.8,{"v":3.9e-30,"d":"3.90E-30"},"KOG3735","Tropomodulin and leiomodulin",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K10370|1|2.3e-38|162.5|tut:107369149|tropomodulin"]
["JAW01133.1",10.06125892,{"$nulls":4},"Hs22060441",161,{"v":1.7e-39,"d":"1.70E-39"},"KOG3774","Uncharacterized conserved protein Lama",null,"T","Signal transduction mechanisms","CELLULAR PROCESSES AND SIGNALING","K04557|1|5.5e-30|134.8|egl:EGR_01732|septin 5"]
["JAW01167.1",10.57671053,null,"GO:0006099//tricarboxylic acid cycle","GO:0003994//aconitate hydratase activity;GO:0046872//metal ion binding;GO:0051539//4 iron, 4 sulfur cluster binding","GO:0005739//mitochondrion","CE25005",250.4,{"v":2.6e-66,"d":"2.60E-66"},"KOG0453","Aconitase/homoaconitase (aconitase superfamily)",null,"CE","Energy production and conversion;Amino acid transport and metabolism","METABOLISM;METABOLISM","K01681|1|4.6e-66|255.0|aplc:110986141|aconitate hydratase [EC:4.2.1.3]"]
["JAW01171.1",7.47224297,null,"GO:0006189//'de novo' IMP biosynthetic process","GO:0004642//phosphoribosylformylglycinamidine synthase activity","GO:0005737//cytoplasm",7297060,216.1,{"v":4.6e-56,"d":"4.60E-56"},"KOG1907","Phosphoribosylformylglycinamidine synthase",null,"F","Nucleotide transport and metabolism","METABOLISM","K01952|1|4.4e-70|268.1|acs:100559217|phosphoribosylformylglycinamidine synthase [EC:6.3.5.3]"]
["JAW01231.1",{"$nulls":3},"GO:0003968//RNA-directed 5'-3' RNA polymerase activity",null,"Hs13569840",236.1,{"v":6.1e-62,"d":"6.10E-62"},"KOG2633","Hismacro and SEC14 domain-containing proteins",null,"BK","Chromatin structure and dynamics;Transcription","INFORMATION STORAGE AND PROCESSING;INFORMATION STORAGE AND PROCESSING","K15212|1|8.7e-64|247.7|bfo:BRAFLDRAFT_123909|TATA box-binding protein-associated factor RNA polymerase I subunit A!K15261|2|3.2e-18|96.3|aam:106498489|poly [ADP-ribose] polymerase 10/14/15 [EC:2.4.2.30]"]
["JAW04567.1",8.431045885]
["JAW01358.1",null,null,"GO:0070507//regulation of microtubule cytoskeleton organization","GO:0008017//microtubule binding;GO:0051010//microtubule plus-end binding","GO:0005874//microtubule","Hs6912494",287.3,{"v":2.6e-77,"d":"2.60E-77"},"KOG3000","Microtubule-binding protein involved in cell cycle control",null,"DZ","Cell cycle control, cell division, chromosome partitioning;Cytoskeleton","CELLULAR PROCESSES AND SIGNALING;CELLULAR PROCESSES AND SIGNALING","K10436|1|6.4e-111|404.4|isc:IscW_ISCW006702|microtubule-associated protein, RP/EB family"]
["XP_064457119.1",10.47506458,null,"GO:0006886//intracellular protein transport;GO:0016192//vesicle-mediated transport","GO:0005525//GTP binding","GO:0005794//Golgi apparatus;GO:0005783//endoplasmic reticulum",7300832,343.2,{"v":2.8e-94,"d":"2.80E-94"},"KOG0077","Vesicle coat complex COPII, GTPase subunit SAR1",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K07953|1|5.3e-104|380.9|isc:IscW_ISCW004922|GTP-binding protein SAR1 [EC:3.6.5.-]"]
["JAW01461.1",10.20038434,null,"GO:0002181//cytoplasmic translation;GO:0006412//translation","GO:0003735//structural constituent of ribosome;GO:0003723//RNA binding","GO:0005840//ribosome;GO:0022625//cytosolic large ribosomal subunit","Hs16579885",411,{"v":1.5e-114,"d":"1.50E-114"},"KOG1475","Ribosomal protein RPL1/RPL2/RL4L4",null,"A","RNA processing and modification","INFORMATION STORAGE AND PROCESSING","K02930|1|1.8e-131|472.6|isc:IscW_ISCW007478|large subunit ribosomal protein L4e"]
["JAW01511.1",9.649687916,{"$nulls":4},"Hs7657599",268.5,{"v":8.9e-72,"d":"8.90E-72"},"KOG1660","Sorting nexin SNX6/TFAF2, contains PX domain",null,"V","Defense mechanisms","CELLULAR PROCESSES AND SIGNALING","K17920|1|1.0e-83|313.5|dpte:113799234|sorting nexin-5/6/32"]
["JAW01625.1",9.084832173,null,"GO:0010591//regulation of lamellipodium assembly;GO:0000902//cell morphogenesis;GO:0051016//barbed-end actin filament capping;GO:0030036//actin cytoskeleton organization;GO:0051490//negative regulation of filopodium assembly","GO:0051015//actin filament binding","GO:0005737//cytoplasm;GO:0005884//actin filament;GO:0008290//F-actin capping protein complex","Hs4826659",273.9,{"v":1.7e-73,"d":"1.70E-73"},"KOG3174","F-actin capping protein, beta subunit",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K10365|1|1.8e-73|279.3|zne:110828160|capping protein (actin filament) muscle Z-line, beta"]
["JAW01836.1",9.639076695,null,null,"GO:0016813//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines;GO:0046872//metal ion binding",null,"Hs13376095",133.3,{"v":4.2e-31,"d":"4.20E-31"},"KOG2964","Arginase family protein",null,"E","Amino acid transport and metabolism","METABOLISM","K01480|1|4.4e-36|155.2|malb:109951221|agmatinase [EC:3.5.3.11]"]
["JAW01903.1",8.729529276,null,"GO:0006886//intracellular protein transport;GO:0006888//ER to Golgi vesicle-mediated transport","GO:0008270//zinc ion binding","GO:0030127//COPII vesicle coat",7296699,315.5,{"v":8.6e-86,"d":"8.60E-86"},"KOG1986","Vesicle coat complex COPII, subunit SEC23",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K14006|1|2.2e-100|369.4|isc:IscW_ISCW016963|protein transport protein SEC23"]
["JAW01916.1",7.967967213,null,null,"GO:0003779//actin binding;GO:0004725//protein tyrosine phosphatase activity;GO:0005543//phospholipid binding",null,7292359,765,{"v":1.2e-220,"d":"1.20E-220"},"KOG0517","Beta-spectrin",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K06115|1|2.6e-234|815.8|phu:Phum_PHUM488290|spectrin beta"]
["JAW01957.1",{"$nulls":3},"GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding;GO:0005524//ATP binding","GO:0016021//integral component of membrane",7294008,960.3,{"v":1.9e-279,"d":"1.90E-279"},"KOG0731","AAA+-type ATPase containing the peptidase M41 domain",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K08956|1|5.3e-306|1053.9|zne:110840035|AFG3 family protein [EC:3.4.24.-]"]
["JAW02000.1",9.707134057,null,"GO:0006081//cellular aldehyde metabolic process","GO:0004030//aldehyde dehydrogenase [NAD(P)+] activity","GO:0016021//integral component of membrane","Hs4557303",484.2,{"v":2.8e-136,"d":"2.80E-136"},"KOG2456","Aldehyde dehydrogenase",null,"C","Energy production and conversion","METABOLISM","K00128|1|3.3e-148|529.3|bter:100646182|aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]"]
["JAW04379.1",null,null,"GO:0009116//nucleoside metabolic process","GO:0003824//catalytic activity",{"$nulls":10},"K18622|1|8.4e-38|161.4|egl:EGR_08562|adducin"]
["JAW02318.1",{"$nulls":5},"Hs17449525",119.4,{"v":4.1e-27,"d":"4.10E-27"},"KOG4214","Myotrophin and similar proteins",null,"K","Transcription","INFORMATION STORAGE AND PROCESSING","K21440|1|2.3e-09|65.9|adf:107342519|ankyrin repeat domain-containing protein 50"]
["JAW02328.1",9.706395573,{"$nulls":4},"Hs6005749",213,{"v":4.7e-55,"d":"4.70E-55"},"KOG2764","Putative transcriptional regulator DJ-1",null,"RV","General function prediction only;Defense mechanisms","POORLY CHARACTERIZED;CELLULAR PROCESSES AND SIGNALING","K05687|1|2.7e-61|239.2|aplc:110979135|protein DJ-1 [EC:3.5.1.124]"]
["JAW02343.1",null,null,"GO:0015992//proton transport;GO:0006740//NADPH regeneration","GO:0050661//NADP binding;GO:0051287//NAD binding;GO:0008746//NAD(P)+ transhydrogenase activity;GO:0008750//NAD(P)+ transhydrogenase (AB-specific) activity","GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane",{"$nulls":9},"K00323|1|0.0e+00|1402.1|dpx:DAPPUDRAFT_315656|H+-translocating NAD(P) transhydrogenase [EC:1.6.1.2 7.1.1.1]"]
["JAW02349.1",9.715770641,null,null,"GO:0003779//actin binding;GO:0005543//phospholipid binding",null,7292359,958,{"v":1.6e-278,"d":"1.60E-278"},"KOG0517","Beta-spectrin",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K06115|1|1.5e-303|1046.6|zne:110838947|spectrin beta"]
["JAW04611.1",null,null,"GO:0007018//microtubule-based movement","GO:0016887//ATPase activity;GO:0005524//ATP binding;GO:0003777//microtubule motor activity","GO:0030286//dynein complex",7292540,955.3,{"v":7.1e-278,"d":"7.10E-278"},"KOG3595","Dyneins, heavy chain",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K10413|1|3.0e-292|1008.4|tut:107362204|dynein heavy chain 1, cytosolic"]
["JAW02397.1",null,null,"GO:0016486//peptide hormone processing;GO:0048703//embryonic viscerocranium morphogenesis","GO:0004222//metalloendopeptidase activity","GO:0016021//integral component of membrane","Hs4503443",273.5,{"v":1.1e-72,"d":"1.10E-72"},"KOG3624","M13 family peptidase",null,"E","Amino acid transport and metabolism","METABOLISM","K01415|1|9.0e-78|295.8|ipu:108255065|endothelin-converting enzyme [EC:3.4.24.71]"]
["JAW02416.1",10.49913359,null,"GO:0006891//intra-Golgi vesicle-mediated transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0016192//vesicle-mediated transport;GO:0030903//notochord development;GO:0006886//intracellular protein transport;GO:0061053//somite development","GO:0005198//structural molecule activity","GO:0005829//cytosol;GO:0000139//Golgi membrane;GO:0030126//COPI vesicle coat","Hs7705369",1328.9,0,"KOG1058","Vesicle coat complex COPI, beta subunit",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K17301|1|0.0e+00|1365.1|lak:106160190|coatomer subunit beta"]
["JAW03535.1",null,9.034037467,"GO:0050688//regulation of defense response to virus;GO:0045087//innate immune response;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0032648//regulation of interferon-beta production;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0030162//regulation of proteolysis;GO:0008063//Toll signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:0042981//regulation of apoptotic process","GO:0031625//ubiquitin protein ligase binding;GO:0031996//thioesterase binding;GO:0019901//protein kinase binding;GO:0019903//protein phosphatase binding;GO:0008270//zinc ion binding;GO:0005164//tumor necrosis factor receptor binding","GO:0035631//CD40 receptor complex;GO:0009898//cytoplasmic side of plasma membrane","HsM4507679",84,{"v":8e-16,"d":"8.00E-16"},"KOG0297","TNF receptor-associated factor",null,"T","Signal transduction mechanisms","CELLULAR PROCESSES AND SIGNALING","K03175|1|3.6e-19|100.5|npr:108787821|TNF receptor-associated factor 6 [EC:2.3.2.27]!K09848|2|1.0e-18|99.0|aqu:100639674|TNF receptor-associated factor 4!K03174|3|1.4e-18|98.6|pss:102461304|TNF receptor-associated factor 3"]
["JAW02479.1",null,null,"GO:0006874//cellular calcium ion homeostasis","GO:0005388//calcium-transporting ATPase activity;GO:0005524//ATP binding","GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane;GO:0005887//integral component of plasma membrane","CE28373",828.2,{"v":1e-239,"d":"1.00E-239"},"KOG0204","Calcium transporting ATPase",null,"P","Inorganic ion transport and metabolism","METABOLISM","K05850|1|0.0e+00|1103.2|isc:IscW_ISCW010968|Ca2+ transporting ATPase, plasma membrane [EC:3.6.3.8]"]
["JAW02495.1",9.315174276,null,"GO:0055085//transmembrane transport","GO:0005215//transporter activity","GO:0016021//integral component of membrane","Hs4503847",393.3,{"v":5.4e-109,"d":"5.40E-109"},"KOG2533","Permease of the major facilitator superfamily",null,"G","Carbohydrate transport and metabolism","METABOLISM","K08171|1|1.4e-152|543.5|isc:IscW_ISCW019000|MFS transporter, OPA family, solute carrier family 37 (glycerol-6-phosphate transporter), member 4"]
["JAW02523.1",8.981404962,null,null,"GO:0046872//metal ion binding;GO:0008253//5'-nucleotidase activity",null,7293456,661,{"v":1.8e-189,"d":"1.80E-189"},"KOG2469","IMP-GMP specific 5'-nucleotidase",null,"F","Nucleotide transport and metabolism","METABOLISM","K01081|1|7.6e-260|900.2|isc:IscW_ISCW002028|5'-nucleotidase [EC:3.1.3.5]"]
["JAW02526.1",9.357971132,null,null,"GO:0016746//transferase activity, transferring acyl groups","GO:0005794//Golgi apparatus",7290756,508.8,{"v":1.4e-143,"d":"1.40E-143"},"KOG1445","Tumor-specific antigen (contains WD repeats)",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K18619|1|1.3e-248|863.2|isc:IscW_ISCW016772|coronin-7"]
["JAW02529.1",8.791765664,null,"GO:0005975//carbohydrate metabolic process;GO:0046168//glycerol-3-phosphate catabolic process","GO:0004367//glycerol-3-phosphate dehydrogenase [NAD+] activity;GO:0051287//NAD binding;GO:0042803//protein homodimerization activity","GO:0009331//glycerol-3-phosphate dehydrogenase complex",7297034,466.5,{"v":4.1e-131,"d":"4.10E-131"},"KOG2711","Glycerol-3-phosphate dehydrogenase/dihydroxyacetone 3-phosphate reductase",null,"C","Energy production and conversion","METABOLISM","K00006|1|6.6e-161|570.9|isc:IscW_ISCW005254|glycerol-3-phosphate dehydrogenase (NAD+) [EC:1.1.1.8]"]
["JAW02543.1",9.36290458,null,"GO:0051604//protein maturation",null,"GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane",{"$nulls":9},"K00858|1|9.0e-10|69.7|tgu:100220598|NAD+ kinase [EC:2.7.1.23]"]
["JAW02562.1",null,null,"GO:0046416//D-amino acid metabolic process","GO:0003884//D-amino-acid oxidase activity;GO:0008445//D-aspartate oxidase activity;GO:0071949//FAD binding",null,"HsM4503255",213.8,{"v":4.3e-55,"d":"4.30E-55"},"KOG3923","D-aspartate oxidase",null,"E","Amino acid transport and metabolism","METABOLISM","K00273|1|2.3e-96|356.3|isc:IscW_ISCW004359|D-amino-acid oxidase [EC:1.4.3.3]!K00272|2|3.4e-63|246.1|lak:106169690|D-aspartate oxidase [EC:1.4.3.1]"]
["JAW06908.1",{"$nulls":3},"GO:0005319//lipid transporter activity","GO:0016021//integral component of membrane",7297621,368.6,{"v":1.4e-101,"d":"1.40E-101"},"KOG1933","Cholesterol transport protein (Niemann-Pick C disease protein)",null,"I","Lipid transport and metabolism","METABOLISM","K12385|1|1.7e-187|659.4|isc:IscW_ISCW006533|Niemann-Pick C1 protein"]
["JAW02573.1",null,null,"GO:0007155//cell adhesion;GO:0031532//actin cytoskeleton reorganization","GO:0003779//actin binding","GO:0016021//integral component of membrane","Hs20127528",403.3,{"v":3.6e-112,"d":"3.60E-112"},"KOG3631","Alpha-parvin and related focal adhesion proteins",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K06275|1|2.0e-150|535.8|isc:IscW_ISCW002088|parvin"]
["JAW04519.1",9.118640304,null,"GO:0016260//selenocysteine biosynthetic process","GO:0004756//selenide, water dikinase activity;GO:0005524//ATP binding",null,7303203,97.4,{"v":1.3e-20,"d":"1.30E-20"},"KOG3939","Selenophosphate synthetase",null,"T","Signal transduction mechanisms","CELLULAR PROCESSES AND SIGNALING","K01008|1|1.5e-27|125.9|isc:IscW_ISCW000849|selenide, water dikinase [EC:2.7.9.3]"]
["JAW02607.1",null,9.828418147,"GO:0016236//macroautophagy","GO:0043130//ubiquitin binding;GO:0008270//zinc ion binding","GO:0000407//phagophore assembly site;GO:0005776//autophagosome","Hs14110375_2",97.1,{"v":1.5e-19,"d":"1.50E-19"},"KOG4351","Uncharacterized conserved protein",null,"S","Function unknown","POORLY CHARACTERIZED","K17987|1|7.1e-243|844.3|isc:IscW_ISCW013255|next to BRCA1 gene 1 protein"]
["JAW02660.1",8.365080404,null,"GO:0006422//aspartyl-tRNA aminoacylation;GO:0006418//tRNA aminoacylation for protein translation","GO:0003676//nucleic acid binding;GO:0004815//aspartate-tRNA ligase activity;GO:0005524//ATP binding","GO:0005737//cytoplasm",7303387,724.5,{"v":1.3e-208,"d":"1.30E-208"},"KOG0556","Aspartyl-tRNA synthetase",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K22503|1|5.8e-225|784.3|aplc:110984532|aspartyl-tRNA synthetase [EC:6.1.1.12]"]
["JAW02699.1",null,null,"GO:0006729//tetrahydrobiopterin biosynthetic process","GO:0004757//sepiapterin reductase activity",null,"Hs4507185",151,{"v":2.9e-36,"d":"2.90E-36"},"KOG1204","Predicted dehydrogenase",null,"Q","Secondary metabolites biosynthesis, transport and catabolism","METABOLISM","K00072|1|3.0e-73|279.3|isc:IscW_ISCW002953|sepiapterin reductase [EC:1.1.1.153]"]
["JAW02757.1",9.297290085,null,"GO:0006096//glycolytic process","GO:0030955//potassium ion binding;GO:0016301//kinase activity;GO:0000287//magnesium ion binding;GO:0004743//pyruvate kinase activity","GO:0005737//cytoplasm","CE15899",641,{"v":1.8e-183,"d":"1.80E-183"},"KOG2323","Pyruvate kinase",null,"G","Carbohydrate transport and metabolism","METABOLISM","K00873|1|3.6e-251|871.3|isc:IscW_ISCW020197|pyruvate kinase [EC:2.7.1.40]"]
["XP_064470640.1",9.098000933,null,"GO:0032264//IMP salvage","GO:0003876//AMP deaminase activity",null,7292938,894.8,{"v":8.9e-260,"d":"8.90E-260"},"KOG1096","Adenosine monophosphate deaminase",null,"F","Nucleotide transport and metabolism","METABOLISM","K01490|1|0.0e+00|1082.0|isc:IscW_ISCW020690|AMP deaminase [EC:3.5.4.6]"]
["JAW02776.1",null,null,"GO:0002181//cytoplasmic translation;GO:0006412//translation;GO:0000027//ribosomal large subunit assembly","GO:0003735//structural constituent of ribosome;GO:0003723//RNA binding","GO:0005840//ribosome;GO:0022625//cytosolic large ribosomal subunit;GO:0016021//integral component of membrane","Hs16753227",226.5,{"v":4.7e-59,"d":"4.70E-59"},"KOG1694","60s ribosomal protein L6",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K02934|1|5.1e-85|318.2|isc:IscW_ISCW016112|large subunit ribosomal protein L6e"]
["JAW06014.1",{"$nulls":3},"GO:0000062//fatty-acyl-CoA binding",null,"Hs14150169",147.5,{"v":2.2e-35,"d":"2.20E-35"},"KOG0817","Acyl-CoA-binding protein",null,"I","Lipid transport and metabolism","METABOLISM","K21440|1|4.3e-10|68.9|tca:657418|ankyrin repeat domain-containing protein 50"]
["XP_064471758.1",9.152018141,null,null,"GO:0005388//calcium-transporting ATPase activity","GO:0005854//nascent polypeptide-associated complex","Hs5031931",259.2,{"v":6.1e-69,"d":"6.10E-69"},"KOG2239","Transcription factor containing NAC and TS-N domains",null,"K","Transcription","INFORMATION STORAGE AND PROCESSING","K03626|1|1.0e-95|353.6|isc:IscW_ISCW012592|nascent polypeptide-associated complex subunit alpha"]
["JAW02861.1",8.876971919,null,"GO:0009072//aromatic amino acid family metabolic process","GO:0004364//glutathione transferase activity;GO:0016034//maleylacetoacetate isomerase activity;GO:0003824//catalytic activity;GO:0016740//transferase activity","GO:0005737//cytoplasm","Hs4504189",246.9,{"v":3.1e-65,"d":"3.10E-65"},"KOG0868","Glutathione S-transferase",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K01800|1|1.5e-83|313.2|isc:IscW_ISCW023198|maleylacetoacetate isomerase [EC:5.2.1.2]"]
["JAW02961.1",9.462538461,null,"GO:0006457//protein folding;GO:0009408//response to heat","GO:0031072//heat shock protein binding;GO:0051082//unfolded protein binding;GO:0046872//metal ion binding;GO:0005524//ATP binding","GO:0005829//cytosol","Hs5031741",517.3,{"v":2.3e-146,"d":"2.30E-146"},"KOG0712","Molecular chaperone (DnaJ superfamily)",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K09503|1|1.9e-199|699.1|isc:IscW_ISCW009131|DnaJ homolog subfamily A member 2"]
["JAW02989.1",null,9.176533426,"GO:0045454//cell redox homeostasis","GO:0015036//disulfide oxidoreductase activity","GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0012505//endomembrane system",7293955,142.9,{"v":3.9e-34,"d":"3.90E-34"},"KOG3384","Selenoprotein",null,"R","General function prediction only","POORLY CHARACTERIZED"]
["XP_064479503.1",null,null,"GO:0048701//embryonic cranial skeleton morphogenesis","GO:0030976//thiamine pyrophosphate binding;GO:0000287//magnesium ion binding;GO:0003824//catalytic activity;GO:0016740//transferase activity","GO:0016021//integral component of membrane","Hs21361361",753.8,{"v":2.3e-217,"d":"2.30E-217"},"KOG1185","Thiamine pyrophosphate-requiring enzyme",null,"EH","Amino acid transport and metabolism;Coenzyme transport and metabolism","METABOLISM;METABOLISM","K11259|1|3.1e-233|812.0|obi:106882700|acetolactate synthase-like protein [EC:2.2.1.-]"]
["JAW03029.1",11.24898862,null,null,"GO:0008738//L-fuculose-phosphate aldolase activity",null,7302481,586.3,{"v":7.6e-167,"d":"7.60E-167"},"KOG3699","Cytoskeletal protein Adducin",null,"TZ","Signal transduction mechanisms;Cytoskeleton","CELLULAR PROCESSES AND SIGNALING;CELLULAR PROCESSES AND SIGNALING","K18622|1|8.1e-273|943.7|isc:IscW_ISCW000621|adducin"]
["JAW03044.1",null,null,"GO:0006888//ER to Golgi vesicle-mediated transport",null,"GO:0016021//integral component of membrane;GO:0030134//COPII-coated ER to Golgi transport vesicle;GO:0030173//integral component of Golgi membrane;GO:0005789//endoplasmic reticulum membrane","Hs7705819",93.6,{"v":1.6e-19,"d":"1.60E-19"},"KOG4779","Predicted membrane protein",null,"S","Function unknown","POORLY CHARACTERIZED","K22939|1|7.5e-20|100.1|isc:IscW_ISCW021098|immediate early response 3-interacting protein 1"]
["JAW03093.1",11.04263038,null,"GO:0007264//small GTPase mediated signal transduction","GO:0003924//GTPase activity;GO:0004767//sphingomyelin phosphodiesterase activity;GO:0005525//GTP binding","GO:0016020//membrane;GO:0005622//intracellular",7293635,366.7,{"v":2.4e-101,"d":"2.40E-101"},"KOG0393","Ras-related small GTPase, Rho type",null,"R","General function prediction only","POORLY CHARACTERIZED","K04393|1|2.8e-105|385.2|isc:IscW_ISCW003614|cell division control protein 42"]
["JAW03117.1",null,9.717365639,"GO:0006069//ethanol oxidation","GO:0008270//zinc ion binding;GO:0051903//S-(hydroxymethyl)glutathione dehydrogenase activity",null,"CE23822",530.4,{"v":2.5e-150,"d":"2.50E-150"},"KOG0022","Alcohol dehydrogenase, class III",null,"Q","Secondary metabolites biosynthesis, transport and catabolism","METABOLISM","K00121|1|3.2e-177|625.2|isc:IscW_ISCW022174|S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]"]
["JAW04840.1",10.34449517,null,"GO:0051301//cell division;GO:0007049//cell cycle","GO:0005525//GTP binding",null,7295512,278.1,{"v":1.2e-74,"d":"1.20E-74"},"KOG2655","Septin family protein (P-loop GTPase)",null,"DZU","Cell cycle control, cell division, chromosome partitioning;Cytoskeleton;Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING;CELLULAR PROCESSES AND SIGNALING;CELLULAR PROCESSES AND SIGNALING","K16942|1|8.5e-89|330.5|isc:IscW_ISCW020030|septin 2"]
["JAW03175.1",{"$nulls":3},"GO:0005524//ATP binding","GO:0005869//dynactin complex;GO:0043209//myelin sheath;GO:0005813//centrosome;GO:0099738//cell cortex region;GO:0070062//extracellular exosome","Hs5031569",649.4,{"v":3.6e-186,"d":"3.60E-186"},"KOG0676","Actin and related proteins",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K16575|1|4.4e-211|737.6|isc:IscW_ISCW022123|centractin"]
["XP_064477201.1",{"$nulls":3},"GO:1990380//Lys48-specific deubiquitinase activity;GO:0004843//thiol-dependent ubiquitin-specific protease activity",null,"Hs14785441",305.8,{"v":1e-82,"d":"1.00E-82"},"KOG2427","Uncharacterized conserved protein",null,"S","Function unknown","POORLY CHARACTERIZED","K01309|1|3.3e-142|508.8|isc:IscW_ISCW010491|ubiquitin carboxyl-terminal hydrolase MINDY-1/2 [EC:3.4.19.12]"]
["JAW03253.1",8.985135031,null,null,"GO:0047131//saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity;GO:0016491//oxidoreductase activity","GO:0016021//integral component of membrane",7299619,340.1,{"v":5.4e-93,"d":"5.40E-93"},"KOG2733","Uncharacterized membrane protein",null,"S","Function unknown","POORLY CHARACTERIZED"]
["JAW03478.1",null,null,"GO:0008152//metabolic process","GO:0052689//carboxylic ester hydrolase activity;GO:0004104//cholinesterase activity","GO:0016021//integral component of membrane","Hs4557239",300.1,{"v":7.7e-81,"d":"7.70E-81"},"KOG4389","Acetylcholinesterase/Butyrylcholinesterase",null,"T","Signal transduction mechanisms","CELLULAR PROCESSES AND SIGNALING","K01050|1|7.1e-114|415.2|isc:IscW_ISCW014411|cholinesterase [EC:3.1.1.8]!K01049|3|5.4e-106|389.0|isc:IscW_ISCW022961|acetylcholinesterase [EC:3.1.1.7]"]
["JAW03542.1",9.51838792,null,"GO:0012501//programmed cell death","GO:0003677//DNA binding","GO:0005634//nucleus;GO:0005829//cytosol",7294171,126.3,{"v":3.7e-29,"d":"3.70E-29"},"KOG3431","Apoptosis-related protein/predicted DNA-binding protein",null,"D","Cell cycle control, cell division, chromosome partitioning","CELLULAR PROCESSES AND SIGNALING","K06875|1|3.0e-42|175.3|isc:IscW_ISCW006407|programmed cell death protein 5"]
["JAW03657.1",null,null,"GO:0006886//intracellular protein transport",null,"GO:0005741//mitochondrial outer membrane;GO:0016021//integral component of membrane","Hs9910382",124,{"v":2.3e-28,"d":"2.30E-28"},"KOG4111","Translocase of outer mitochondrial membrane complex, subunit TOM22",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K17769|1|2.3e-31|139.4|tca:658454|mitochondrial import receptor subunit TOM22"]
["JAW03680.1",9.624309963,null,null,"GO:0004842//ubiquitin-protein transferase activity",null,7297702,360.9,{"v":1.9e-99,"d":"1.90E-99"},"KOG4642","Chaperone-dependent E3 ubiquitin protein ligase (contains TPR repeats)",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K09561|1|2.8e-106|389.0|zne:110830289|STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]"]
["JAW03788.1",null,null,"GO:0044237//cellular metabolic process","GO:0008017//microtubule binding;GO:0016740//transferase activity;GO:0005542//folic acid binding","GO:0030868//smooth endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0000139//Golgi membrane;GO:0070062//extracellular exosome",{"$nulls":9},"K13990|1|8.5e-200|700.7|lak:106175096|glutamate formiminotransferase / formiminotetrahydrofolate cyclodeaminase [EC:2.1.2.5 4.3.1.4]"]
["JAW04054.1",null,null,"GO:0006491//N-glycan processing","GO:0016301//kinase activity;GO:0005509//calcium ion binding","GO:0016021//integral component of membrane",7298396,285,{"v":2.1e-76,"d":"2.10E-76"},"KOG2397","Protein kinase C substrate, 80 KD protein, heavy chain",null,"T","Signal transduction mechanisms","CELLULAR PROCESSES AND SIGNALING","K08288|1|7.5e-122|441.4|isc:IscW_ISCW013550|protein kinase C substrate 80K-H"]
["JAW05353.1",8.864191376,null,null,"GO:0046983//protein dimerization activity;GO:0050660//flavin adenine dinucleotide binding;GO:0016491//oxidoreductase activity",null,"Hs4757732",536.6,{"v":4.6e-152,"d":"4.60E-152"},"KOG1346","Programmed cell death 8 (apoptosis-inducing factor)",null,"T","Signal transduction mechanisms","CELLULAR PROCESSES AND SIGNALING","K04727|1|4.6e-163|578.6|dpx:DAPPUDRAFT_189511|apoptosis-inducing factor 1 [EC:1.-.-.-]"]
["JAW04144.1",null,null,"GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0050852//T cell receptor signaling pathway;GO:0042346//positive regulation of NF-kappaB import into nucleus;GO:0060546//negative regulation of necroptotic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:0097039//protein linear polyubiquitination;GO:0032088//negative regulation of NF-kappaB transcription factor activity","GO:0043130//ubiquitin binding;GO:0046872//metal ion binding;GO:0004842//ubiquitin-protein transferase activity","GO:0071797//LUBAC complex","Hs5454168",68.9,{"v":3.2e-11,"d":"3.20E-11"},"KOG1815","Predicted E3 ubiquitin ligase",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K10630|1|6.5e-36|156.4|isc:IscW_ISCW021616|RanBP-type and C3HC4-type zinc finger-containing protein 1 [EC:2.3.2.31]"]
["JAW04171.1",null,null,"GO:0006810//transport",null,"GO:0016021//integral component of membrane","CE02827",360.9,{"v":2e-99,"d":"2.00E-99"},"KOG0759","Mitochondrial oxoglutarate/malate carrier proteins",null,"C","Energy production and conversion","METABOLISM","K13577|1|3.9e-103|378.6|phu:Phum_PHUM235410|solute carrier family 25 (mitochondrial dicarboxylate transporter), member 10"]
["JAW04210.1",null,null,"GO:0000338//protein deneddylation;GO:0010387//COP9 signalosome assembly",null,"GO:0005737//cytoplasm;GO:0008180//COP9 signalosome","Hs5729779",171.4,{"v":1.4e-42,"d":"1.40E-42"},"KOG4414","COP9 signalosome, subunit CSN8",null,"OT","Posttranslational modification, protein turnover, chaperones;Signal transduction mechanisms","CELLULAR PROCESSES AND SIGNALING;CELLULAR PROCESSES AND SIGNALING","K12181|1|3.7e-46|188.7|xla:443917|COP9 signalosome complex subunit 8"]
["JAW04617.1",9.54408847,null,"GO:0043418//homocysteine catabolic process;GO:0009636//response to toxic substance","GO:0004197//cysteine-type endopeptidase activity;GO:0008234//cysteine-type peptidase activity","GO:0005829//cytosol",7290931,547,{"v":3e-155,"d":"3.00E-155"},"KOG4128","Bleomycin hydrolases and aminopeptidases of cysteine protease family",null,"E","Amino acid transport and metabolism","METABOLISM","K01372|1|9.4e-160|567.4|zne:110837928|bleomycin hydrolase [EC:3.4.22.40]"]
["JAW04872.1",null,9.464109197,"GO:0006511//ubiquitin-dependent protein catabolic process","GO:0004298//threonine-type endopeptidase activity","GO:0005737//cytoplasm;GO:0019773//proteasome core complex, alpha-subunit complex;GO:0005634//nucleus","Hs4506183",369.8,{"v":3.7e-102,"d":"3.70E-102"},"KOG0184","20S proteasome, regulatory subunit alpha type PSMA3/PRE10",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K02727|1|1.2e-127|459.9|isc:IscW_ISCW005463|20S proteasome subunit alpha 7 [EC:3.4.25.1]"]
["JAW05099.1",null,9.328577667,null,null,"GO:0016021//integral component of membrane",{"$nulls":9},"K05357|1|1.9e-38|162.5|isc:IscW_ISCW024282|vitamin-K-epoxide reductase (warfarin-sensitive) [EC:1.17.4.4]"]
["JAW05142.1",9.054973479,null,null,"GO:0016887//ATPase activity;GO:0043023//ribosomal large subunit binding;GO:0043022//ribosome binding;GO:0005524//ATP binding;GO:0005525//GTP binding","GO:0005737//cytoplasm",7291084,612.1,{"v":6.8e-175,"d":"6.80E-175"},"KOG1491","Predicted GTP-binding protein (ODN superfamily)",null,"R","General function prediction only","POORLY CHARACTERIZED","K19788|1|1.3e-216|756.1|isc:IscW_ISCW007252|obg-like ATPase 1"]
["JAW05145.1",8.855514485,null,"GO:0006796//phosphate-containing compound metabolic process","GO:0000287//magnesium ion binding;GO:0004427//inorganic diphosphatase activity","GO:0005737//cytoplasm",7291807,251.5,{"v":1.3e-66,"d":"1.30E-66"},"KOG1626","Inorganic pyrophosphatase/Nucleosome remodeling factor, subunit NURF38",null,"C","Energy production and conversion","METABOLISM","K11726|1|2.9e-77|292.4|isc:IscW_ISCW000237|nucleosome-remodeling factor 38 kDa subunit [EC:3.6.1.1]"]
["JAW05165.1",10.4130261,null,"GO:0006090//pyruvate metabolic process;GO:0006094//gluconeogenesis","GO:0046872//metal ion binding;GO:0004736//pyruvate carboxylase activity;GO:0009374//biotin binding;GO:0004075//biotin carboxylase activity;GO:0005524//ATP binding",null,7303838,537.7,{"v":1.5e-152,"d":"1.50E-152"},"KOG0369","Pyruvate carboxylase",null,"C","Energy production and conversion","METABOLISM","K01958|1|1.0e-154|550.4|tca:662701|pyruvate carboxylase [EC:6.4.1.1]"]
["JAW05198.1",8.647628904,null,"GO:0046835//carbohydrate phosphorylation","GO:0016301//kinase activity;GO:0045127//N-acetylglucosamine kinase activity","GO:0070062//extracellular exosome",7300002,222.2,{"v":9.2e-58,"d":"9.20E-58"},"KOG1794","N-Acetylglucosamine kinase",null,"G","Carbohydrate transport and metabolism","METABOLISM","K00884|1|1.4e-74|283.5|isc:IscW_ISCW007523|N-acetylglucosamine kinase [EC:2.7.1.59]"]
["XP_064471088.1",{"$nulls":3},"GO:0016874//ligase activity",null,"Hs11545863",815.5,{"v":5.7e-236,"d":"5.70E-236"},"KOG0540","3-Methylcrotonyl-CoA carboxylase, non-biotin containing subunit/Acetyl-CoA carboxylase carboxyl transferase, subunit beta",null,"EI","Amino acid transport and metabolism;Lipid transport and metabolism","METABOLISM;METABOLISM","K01969|1|7.4e-247|857.1|xma:102228709|3-methylcrotonyl-CoA carboxylase beta subunit [EC:6.4.1.4]"]
["JAW05246.1",null,null,"GO:0006396//RNA processing","GO:0003723//RNA binding","GO:0005634//nucleus;GO:0030529//intracellular ribonucleoprotein complex","Hs10835067",203.8,{"v":5.2e-52,"d":"5.20E-52"},"KOG4213","RNA-binding protein La",null,"A","RNA processing and modification","INFORMATION STORAGE AND PROCESSING","K11090|1|4.7e-64|249.2|xma:102232966|lupus La protein"]
["JAW05297.1",null,null,"GO:0006007//glucose catabolic process","GO:0004619//phosphoglycerate mutase activity;GO:0030145//manganese ion binding","GO:0005737//cytoplasm","CE11302",278.5,{"v":1.4e-74,"d":"1.40E-74"},"KOG4513","Phosphoglycerate mutase",null,"G","Carbohydrate transport and metabolism","METABOLISM","K15633|1|6.1e-89|331.6|isc:IscW_ISCW020443|2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]"]
["JAW05388.1",{"$nulls":3},"GO:0016740//transferase activity;GO:0004867//serine-type endopeptidase inhibitor activity","GO:0005615//extracellular space","Hs13489087",227.3,{"v":4.8e-59,"d":"4.80E-59"},"KOG2392","Serpin",null,"V","Defense mechanisms","CELLULAR PROCESSES AND SIGNALING","K13963|1|7.6e-60|235.3|bfo:BRAFLDRAFT_130749|serpin B"]
["JAW05516.1",7.286019364,null,"GO:0006139//nucleobase-containing compound metabolic process;GO:0006221//pyrimidine nucleotide biosynthetic process;GO:0006207//'de novo' pyrimidine nucleobase biosynthetic process;GO:0046034//ATP metabolic process","GO:0019205//nucleobase-containing compound kinase activity;GO:0004127//cytidylate kinase activity;GO:0004017//adenylate kinase activity;GO:0009041//uridylate kinase activity;GO:0005524//ATP binding","GO:0005737//cytoplasm","Hs4502011",204.1,{"v":2.1e-52,"d":"2.10E-52"},"KOG3079","Uridylate kinase/adenylate kinase",null,"F","Nucleotide transport and metabolism","METABOLISM","K00939|1|7.6e-74|280.8|isc:IscW_ISCW000200|adenylate kinase [EC:2.7.4.3]"]
["JAW05626.1",8.897771311,null,"GO:0007155//cell adhesion;GO:0007229//integrin-mediated signaling pathway","GO:0004621//glycosylphosphatidylinositol phospholipase D activity","GO:0008305//integrin complex","Hs4504749",326.6,{"v":1.5e-88,"d":"1.50E-88"},"KOG3637","Vitronectin receptor, alpha subunit",null,"W","Extracellular structures","CELLULAR PROCESSES AND SIGNALING","K06483|1|6.3e-106|389.8|lak:106158252|integrin alpha 4!K06585|3|4.8e-98|363.6|aplc:110975847|integrin alpha 9"]
["JAW05754.1",8.280179172,null,"GO:0006633//fatty acid biosynthetic process","GO:0050080//malonyl-CoA decarboxylase activity",null,"Hs6912498",372.9,{"v":8e-103,"d":"8.00E-103"},"KOG3018","Malonyl-CoA decarboxylase",null,"G","Carbohydrate transport and metabolism","METABOLISM","K01578|1|5.6e-136|488.4|isc:IscW_ISCW010433|malonyl-CoA decarboxylase [EC:4.1.1.9]"]
["JAW05861.1",9.733452564,null,"GO:0006886//intracellular protein transport;GO:0016192//vesicle-mediated transport","GO:0005198//structural molecule activity","GO:0030126//COPI vesicle coat;GO:0000139//Golgi membrane","Hs6912320",1175.6,0,"KOG1078","Vesicle coat complex COPI, gamma subunit",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K17267|1|0.0e+00|1283.1|isc:IscW_ISCW022475|coatomer subunit gamma"]
["JAW05867.1",null,null,"GO:0009165//nucleotide biosynthetic process;GO:0009116//nucleoside metabolic process","GO:0004749//ribose phosphate diphosphokinase activity;GO:0000287//magnesium ion binding",null,"Hs4506131",223.4,{"v":2.6e-58,"d":"2.60E-58"},"KOG1503","Phosphoribosylpyrophosphate synthetase-associated protein",null,"EF","Amino acid transport and metabolism;Nucleotide transport and metabolism","METABOLISM;METABOLISM","K00948|1|2.7e-26|122.5|tad:TRIADDRAFT_25357|ribose-phosphate pyrophosphokinase [EC:2.7.6.1]"]
["JAW06066.1",null,8.940644619,{"$nulls":3},"Hs8922999",321.6,{"v":2.4e-87,"d":"2.40E-87"},"KOG1981","SOK1 kinase belonging to the STE20/SPS1/GC kinase family",null,"T","Signal transduction mechanisms","CELLULAR PROCESSES AND SIGNALING"]
["JAW06111.1",8.962795567,null,"GO:0006807//nitrogen compound metabolic process","GO:0000257//nitrilase activity;GO:0016810//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds",null,"Hs9910460",374.4,{"v":1.7e-103,"d":"1.70E-103"},"KOG0806","Carbon-nitrogen hydrolase",null,"E","Amino acid transport and metabolism","METABOLISM","K13566|1|1.1e-123|446.8|isc:IscW_ISCW017251|omega-amidase [EC:3.5.1.3]"]
["JAW06196.1",null,9.795831916,"GO:0006542//glutamine biosynthetic process","GO:0004356//glutamate-ammonia ligase activity;GO:0005524//ATP binding",null,7292645,341.7,{"v":1.6e-93,"d":"1.60E-93"},"KOG0683","Glutamine synthetase",null,"E","Amino acid transport and metabolism","METABOLISM","K01915|1|2.5e-99|366.3|lgi:LOTGIDRAFT_230064|glutamine synthetase [EC:6.3.1.2]"]
["JAW06279.1",null,null,"GO:0006107//oxaloacetate metabolic process","GO:0008816//citryl-CoA lyase activity;GO:0016829//lyase activity;GO:0000287//magnesium ion binding;GO:0003824//catalytic activity;GO:0046872//metal ion binding",{"$nulls":10},"K11390|1|2.9e-95|352.4|isc:IscW_ISCW009007|citrate lyase subunit beta-like protein [EC:4.1.-.-]"]
["JAW06365.1",null,null,"GO:0006457//protein folding;GO:1902175//regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:0019511//peptidyl-proline hydroxylation;GO:0045454//cell redox homeostasis;GO:0034976//response to endoplasmic reticulum stress","GO:0003756//protein disulfide isomerase activity;GO:0016757//transferase activity, transferring glycosyl groups","GO:0005783//endoplasmic reticulum",7294310,568.5,{"v":1.1e-161,"d":"1.10E-161"},"KOG0190","Protein disulfide isomerase (prolyl 4-hydroxylase beta subunit)",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K09580|1|6.0e-208|727.6|isc:IscW_ISCW010827|protein disulfide-isomerase A1 [EC:5.3.4.1]"]
["XP_064480384.1",10.47664743,null,"GO:0006412//translation;GO:0000027//ribosomal large subunit assembly","GO:0008097//5S rRNA binding;GO:0003735//structural constituent of ribosome","GO:0005840//ribosome;GO:0022625//cytosolic large ribosomal subunit","Hs14591909",468.4,{"v":9.2e-132,"d":"9.20E-132"},"KOG0875","60S ribosomal protein L5",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K02932|1|1.1e-132|476.9|xla:379064|large subunit ribosomal protein L5e"]
["JAW06431.1",9.969775112,null,"GO:0010591//regulation of lamellipodium assembly;GO:0007015//actin filament organization;GO:0006909//phagocytosis;GO:0000902//cell morphogenesis;GO:0051016//barbed-end actin filament capping;GO:0035220//wing disc development;GO:0051490//negative regulation of filopodium assembly;GO:0007294//germarium-derived oocyte fate determination;GO:0046329//negative regulation of JNK cascade","GO:0046982//protein heterodimerization activity;GO:0003779//actin binding","GO:0016324//apical plasma membrane;GO:0005912//adherens junction;GO:0008290//F-actin capping protein complex",7291228,245,{"v":9.3e-65,"d":"9.30E-65"},"KOG0836","F-actin capping protein, alpha subunit",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K10364|1|6.2e-64|247.7|pcf:106784534|capping protein (actin filament) muscle Z-line, alpha"]
["JAW06450.1",10.31814859,null,"GO:0006886//intracellular protein transport","GO:0008536//Ran GTPase binding","GO:0005622//intracellular","Hs19923142",1264.6,0,"KOG1241","Karyopherin (importin) beta 1",null,"YU","Nuclear structure;Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING;CELLULAR PROCESSES AND SIGNALING","K14293|1|0.0e+00|1310.4|crg:105317890|importin subunit beta-1"]
["XP_064471799.1",null,null,"GO:0006412//translation","GO:0003735//structural constituent of ribosome","GO:0005840//ribosome",7291488,266.2,{"v":3.2e-71,"d":"3.20E-71"},"KOG0901","60S ribosomal protein L14/L17/L23",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K02894|1|1.1e-71|273.1|clec:106674185|large subunit ribosomal protein L23e"]
["JAW06695.1",8.481740633,null,"GO:0030100//regulation of endocytosis","GO:0004767//sphingomyelin phosphodiesterase activity;GO:0003924//GTPase activity;GO:0005525//GTP binding","GO:0005769//early endosome","Hs7661922",273.5,{"v":2.5e-73,"d":"2.50E-73"},"KOG0088","GTPase Rab21, small G protein superfamily",null,"R","General function prediction only","POORLY CHARACTERIZED","K07890|1|2.9e-80|302.0|isc:IscW_ISCW017002|Ras-related protein Rab-21"]
["JAW06742.1",9.75082726,{"$nulls":4},"Hs5803181",355.9,{"v":2.2e-97,"d":"2.20E-97"},"KOG0548","Molecular co-chaperone STI1",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K09553|1|1.8e-113|414.8|tut:107368957|stress-induced-phosphoprotein 1"]
["JAW06791.1",8.705097851,null,"GO:0051301//cell division","GO:0005525//GTP binding","GO:0031105//septin complex","Hs22062766",586.6,{"v":3.9e-167,"d":"3.90E-167"},"KOG2655","Septin family protein (P-loop GTPase)",null,"DZU","Cell cycle control, cell division, chromosome partitioning;Cytoskeleton;Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING;CELLULAR PROCESSES AND SIGNALING;CELLULAR PROCESSES AND SIGNALING","K16944|1|1.0e-186|657.1|isc:IscW_ISCW018169|septin 7"]
["JAW06819.1",10.40253946,null,"GO:0006301//postreplication repair;GO:0070534//protein K63-linked ubiquitination","GO:0031625//ubiquitin protein ligase binding;GO:0061630//ubiquitin protein ligase activity;GO:0016874//ligase activity;GO:0005524//ATP binding","GO:0005737//cytoplasm;GO:0005634//nucleus","Hs4507793",282,{"v":6.1e-76,"d":"6.10E-76"},"KOG0417","Ubiquitin-protein ligase",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K10580|1|1.8e-78|295.8|isc:IscW_ISCW006743|ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"]
["JAW06835.1",null,10.15737027,null,"GO:0016671//oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor;GO:0003756//protein disulfide isomerase activity","GO:0005783//endoplasmic reticulum","Hs9845249",453,{"v":6e-127,"d":"6.00E-127"},"KOG2608","Endoplasmic reticulum membrane-associated oxidoreductin involved in disulfide bond formation",null,"OU","Posttranslational modification, protein turnover, chaperones;Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING;CELLULAR PROCESSES AND SIGNALING","K10950|1|4.0e-142|508.8|clec:106669172|ERO1-like protein alpha [EC:1.8.4.-]"]
["JAW06945.1",8.840459242,null,null,"GO:0003746//translation elongation factor activity","GO:0070449//elongin complex;GO:0030891//VCB complex","Hs6005890",130.6,{"v":1.8e-30,"d":"1.80E-30"},"KOG4495","RNA polymerase II transcription elongation factor Elongin/SIII, subunit elongin B",null,"K","Transcription","INFORMATION STORAGE AND PROCESSING","K03873|1|4.9e-52|207.6|isc:IscW_ISCW002622|elongin-B"]
["XP_064454744.1",null,12.80655766,"GO:0060271//cilium assembly;GO:0042073//intraciliary transport","GO:0015631//tubulin binding","GO:0031514//motile cilium;GO:0030992//intraciliary transport particle B","Hs12667788",85.1,{"v":4.9e-16,"d":"4.90E-16"},"KOG0161","Myosin class II heavy chain",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K19677|1|1.9e-193|679.9|lak:106177642|intraflagellar transport protein 81"]
["XP_064455436.1",10.86758791,{"$nulls":4},"Hs10947036",172.2,{"v":4.4e-42,"d":"4.40E-42"},"KOG4177","Ankyrin",null,"M","Cell wall/membrane/envelope biogenesis","CELLULAR PROCESSES AND SIGNALING","K10380|1|2.2e-44|185.3|cpic:101942433|ankyrin"]
["XP_064455538.1",null,9.749676182,null,"GO:0004386//helicase activity;GO:0005524//ATP binding;GO:0003743//translation initiation factor activity",null,"Hs4503531",667.9,{"v":1.1e-191,"d":"1.10E-191"},"KOG0327","Translation initiation factor 4F, helicase subunit (eIF-4A) and related helicases",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K03257|1|8.0e-206|720.3|zne:110833474|translation initiation factor 4A"]
["XP_064456274.1",8.33522316,null,"GO:0006606//protein import into nucleus;GO:0006607//NLS-bearing protein import into nucleus","GO:0008565//protein transporter activity;GO:0008139//nuclear localization sequence binding","GO:0005737//cytoplasm;GO:0005643//nuclear pore;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol","Hs4504901",782.7,{"v":3.8e-226,"d":"3.80E-226"},"KOG0166","Karyopherin (importin) alpha",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K15043|1|1.1e-161|573.9|lak:106169111|importin subunit alpha-2"]
["XP_064456382.1",9.760321837,null,"GO:0007018//microtubule-based movement","GO:0008017//microtubule binding;GO:0005524//ATP binding;GO:0003777//microtubule motor activity","GO:0005874//microtubule",7302958,1317.4,0,"KOG0240","Kinesin (SMY1 subfamily)",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K10396|1|0.0e+00|1437.9|tut:107363877|kinesin family member 5"]
["XP_064457362.1",null,null,"GO:1905344//prostaglandin catabolic process;GO:0052651//monoacylglycerol catabolic process","GO:0047372//acylglycerol lipase activity","GO:0016021//integral component of membrane","Hs15100151",525.4,{"v":1.2e-148,"d":"1.20E-148"},"KOG1553","Predicted alpha/beta hydrolase BAT5",null,"R","General function prediction only","POORLY CHARACTERIZED","K08869|1|2.2e-94|350.5|dpl:KGM_201356|aarF domain-containing kinase"]
["XP_064457379.1",10.2598316,null,null,"GO:0004721//phosphoprotein phosphatase activity",null,"Hs4758952",628.2,{"v":7.2e-180,"d":"7.20E-180"},"KOG0371","Serine/threonine protein phosphatase 2A, catalytic subunit",null,"T","Signal transduction mechanisms","CELLULAR PROCESSES AND SIGNALING","K04382|1|9.0e-186|653.3|isc:IscW_ISCW014549|serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]"]
["XP_064457624.1",9.874472029,null,null,"GO:0003755//peptidyl-prolyl cis-trans isomerase activity",null,"Hs5453898",189.9,{"v":3.4e-48,"d":"3.40E-48"},"KOG3259","Peptidyl-prolyl cis-trans isomerase",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K09578|1|5.7e-59|231.1|dpa:109539481|peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 [EC:5.2.1.8]"]
["XP_064458005.1",null,null,"GO:0006631//fatty acid metabolic process","GO:0003857//3-hydroxyacyl-CoA dehydrogenase activity;GO:0070403//NAD+ binding",null,"Hs4885387",388.7,{"v":9.5e-108,"d":"9.50E-108"},"KOG2304","3-hydroxyacyl-CoA dehydrogenase",null,"I","Lipid transport and metabolism","METABOLISM","K00022|1|3.7e-139|498.4|isc:IscW_ISCW014460|3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35]"]
["XP_064458123.1",null,9.934983785,{"$nulls":3},7298525,382.1,{"v":1.2e-105,"d":"1.20E-105"},"KOG2693","Putative zinc transporter",null,"P","Inorganic ion transport and metabolism","METABOLISM","K14713|1|2.9e-115|419.5|dpx:DAPPUDRAFT_220710|solute carrier family 39 (zinc transporter), member 7"]
["XP_064458217.1",8.68427223,{"$nulls":3},"GO:0005737//cytoplasm","Hs7705773",370.9,{"v":2.3e-102,"d":"2.30E-102"},"KOG3725","SH3 domain protein SH3GLB",null,"T","Signal transduction mechanisms","CELLULAR PROCESSES AND SIGNALING","K11248|1|1.8e-147|526.2|isc:IscW_ISCW000293|endophilin-B1"]
["XP_064458303.1",10.43126259,null,null,"GO:0005544//calcium-dependent phospholipid binding;GO:0005509//calcium ion binding",null,"Hs4809276",303.1,{"v":5.3e-82,"d":"5.30E-82"},"KOG0819","Annexin",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K17095|1|1.3e-86|323.9|aqu:100638289|annexin A7/11"]
["XP_064458416.1",null,9.586654567,"GO:0006904//vesicle docking involved in exocytosis",null,null,7292440,827.8,{"v":1.2e-239,"d":"1.20E-239"},"KOG1300","Vesicle trafficking protein Sec1",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K15292|1|0.0e+00|1117.8|isc:IscW_ISCW002599|syntaxin-binding protein 1"]
["XP_064458507.1",null,null,"GO:0006487//protein N-linked glycosylation;GO:0006047//UDP-N-acetylglucosamine metabolic process;GO:0006002//fructose 6-phosphate metabolic process","GO:0004044//amidophosphoribosyltransferase activity;GO:0097367//carbohydrate derivative binding;GO:0004360//glutamine-fructose-6-phosphate transaminase (isomerizing) activity",null,7289004,995.3,{"v":4.9e-290,"d":"4.90E-290"},"KOG1268","Glucosamine 6-phosphate synthetases, contain amidotransferase and phosphosugar isomerase domains",null,"M","Cell wall/membrane/envelope biogenesis","CELLULAR PROCESSES AND SIGNALING","K00820|1|0.0e+00|1102.8|isc:IscW_ISCW009866|glucosamine---fructose-6-phosphate aminotransferase (isomerizing) [EC:2.6.1.16]"]
["XP_064458526.1",7.604523149,null,"GO:0055085//transmembrane transport","GO:0005215//transporter activity","GO:0016021//integral component of membrane","CE27109",619,{"v":7.9e-177,"d":"7.90E-177"},"KOG3761","Choline transporter",null,"I","Lipid transport and metabolism","METABOLISM","K14387|1|7.0e-237|823.9|dpte:113790730|solute carrier family 5 (high affinity choline transporter), member 7"]
["XP_064458714.1",9.241178696,{"$nulls":3},"GO:0016021//integral component of membrane","Hs14744802",961.1,{"v":8.7e-280,"d":"8.70E-280"},"KOG1277","Endosomal membrane proteins, EMP70",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K17087|1|1.5e-311|1072.0|isc:IscW_ISCW012909|transmembrane 9 superfamily member 3"]
["XP_064458824.1",null,null,"GO:0008360//regulation of cell shape;GO:0044331//cell-cell adhesion mediated by cadherin;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules","GO:0005509//calcium ion binding","GO:0016021//integral component of membrane;GO:0035003//subapical complex;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane",7299907,292,{"v":6.6e-78,"d":"6.60E-78"},"KOG3594","FOG: Cadherin repeats",null,"S","Function unknown","POORLY CHARACTERIZED","K06813|1|4.3e-56|224.9|xla:108697217|cadherin 23"]
["XP_064459095.1",{"$nulls":4},"GO:0005829//cytosol;GO:0005886//plasma membrane","Hs11072093",161,{"v":1.1e-38,"d":"1.10E-38"},"KOG0974","WD-repeat protein WDR6, WD repeat superfamily",null,"R","General function prediction only","POORLY CHARACTERIZED","K06711|1|2.3e-34|152.1|fch:102046917|hypoxia-inducible factor prolyl 4-hydroxylase [EC:1.14.11.-]!K01053|2|5.6e-25|120.9|api:100164880|gluconolactonase [EC:3.1.1.17]!K09008|3|4.0e-23|114.8|phi:102108507|NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3!K14555|5|4.3e-09|68.2|zne:110838261|U3 small nucleolar RNA-associated protein 13"]
["XP_064459255.1",{"$nulls":3},"GO:0004725//protein tyrosine phosphatase activity;GO:0016740//transferase activity;GO:0050254//rhodopsin kinase activity","GO:0005737//cytoplasm","Hs18375642",754.6,{"v":1.4e-217,"d":"1.40E-217"},"KOG0790","Protein tyrosine phosphatase Corkscrew and related SH2 domain enzymes",null,"T","Signal transduction mechanisms","CELLULAR PROCESSES AND SIGNALING","K07293|1|9.7e-307|1056.2|isc:IscW_ISCW012894|tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]"]
["XP_064459280.1",{"$nulls":5},"Hs22060441",529.3,{"v":8.2e-150,"d":"8.20E-150"},"KOG3774","Uncharacterized conserved protein Lama",null,"T","Signal transduction mechanisms","CELLULAR PROCESSES AND SIGNALING","K04557|1|5.6e-85|319.3|egl:EGR_01732|septin 5"]
["XP_064460137.1",10.31624345,null,"GO:0007017//microtubule-based process;GO:0060271//cilium assembly;GO:0010970//transport along microtubule;GO:2000582//positive regulation of ATP-dependent microtubule motor activity, plus-end-directed","GO:0008092//cytoskeletal protein binding;GO:0051959//dynein light intermediate chain binding;GO:0045505//dynein intermediate chain binding","GO:0005737//cytoplasm;GO:0016459//myosin complex;GO:0043186//P granule;GO:0005634//nucleus;GO:0005868//cytoplasmic dynein complex;GO:0030286//dynein complex",7290522,179.5,{"v":2.5e-45,"d":"2.50E-45"},"KOG3430","Dynein light chain type 1",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K10418|1|7.5e-45|183.3|isc:IscW_ISCW003606|dynein light chain LC8-type"]
["XP_064460794.1",9.517685567,null,"GO:0006006//glucose metabolic process;GO:0006096//glycolytic process","GO:0051287//NAD binding;GO:0004365//glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity;GO:0050661//NADP binding",null,7293147,525,{"v":9.7e-149,"d":"9.70E-149"},"KOG0657","Glyceraldehyde 3-phosphate dehydrogenase",null,"G","Carbohydrate transport and metabolism","METABOLISM","K00134|1|1.1e-174|616.7|isc:IscW_ISCW018700|glyceraldehyde 3-phosphate dehydrogenase [EC:1.2.1.12]"]
["XP_064472170.1",8.44896757,null,"GO:0006879//cellular iron ion homeostasis;GO:0008152//metabolic process;GO:0010040//response to iron(II) ion","GO:0051539//4 iron, 4 sulfur cluster binding;GO:0003994//aconitate hydratase activity","GO:0005737//cytoplasm","Hs8659555",1278.5,0,"KOG0452","RNA-binding translational regulator IRP (aconitase superfamily)",null,"AJ","RNA processing and modification;Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING;INFORMATION STORAGE AND PROCESSING","K01681|1|0.0e+00|1350.1|phu:Phum_PHUM449620|aconitate hydratase [EC:4.2.1.3]"]
["XP_064464203.1",null,null,"GO:0009966//regulation of signal transduction",null,null,"Hs4557663",213,{"v":8.1e-55,"d":"8.10E-55"},"KOG2830","Protein phosphatase 2A-associated protein",null,"T","Signal transduction mechanisms","CELLULAR PROCESSES AND SIGNALING","K17606|1|9.4e-67|258.1|obi:106870712|immunoglobulin-binding protein 1"]
["XP_064465618.1",null,null,"GO:0006099//tricarboxylic acid cycle","GO:0004449//isocitrate dehydrogenase (NAD+) activity;GO:0000287//magnesium ion binding;GO:0051287//NAD binding","GO:0005739//mitochondrion",7300799,474.9,{"v":1.3e-133,"d":"1.30E-133"},"KOG0784","Isocitrate dehydrogenase, gamma subunit",null,"E","Amino acid transport and metabolism","METABOLISM","K00030|1|2.4e-151|539.3|dpte:113797315|isocitrate dehydrogenase (NAD+) [EC:1.1.1.41]"]
["XP_064465888.1",{"$nulls":5},7302481,583.6,{"v":5e-166,"d":"5.00E-166"},"KOG3699","Cytoskeletal protein Adducin",null,"TZ","Signal transduction mechanisms;Cytoskeleton","CELLULAR PROCESSES AND SIGNALING;CELLULAR PROCESSES AND SIGNALING","K18622|1|3.1e-272|941.8|isc:IscW_ISCW000621|adducin"]
["XP_064466097.1",9.355639518,null,"GO:0007032//endosome organization;GO:0007030//Golgi organization;GO:0046854//phosphatidylinositol phosphorylation","GO:0016301//kinase activity;GO:0004430//1-phosphatidylinositol 4-kinase activity","GO:0005802//trans-Golgi network;GO:0005765//lysosomal membrane;GO:0005886//plasma membrane;GO:0005768//endosome","Hs22044130",545.8,{"v":6.3e-155,"d":"6.30E-155"},"KOG2381","Phosphatidylinositol 4-kinase",null,"T","Signal transduction mechanisms","CELLULAR PROCESSES AND SIGNALING","K13711|1|2.8e-174|615.5|isc:IscW_ISCW016535|phosphatidylinositol 4-kinase type 2 [EC:2.7.1.67]"]
["XP_064466148.1",null,10.36843746,"GO:0006457//protein folding","GO:0051082//unfolded protein binding",null,7296201,501.5,{"v":1.2e-141,"d":"1.20E-141"},"KOG0713","Molecular chaperone (DnaJ superfamily)",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K09517|1|5.1e-177|624.4|isc:IscW_ISCW021534|DnaJ homolog subfamily B member 11"]
["XP_064466208.1",8.944802842,null,"GO:0009052//pentose-phosphate shunt, non-oxidative branch","GO:0004751//ribose-5-phosphate isomerase activity",null,"Hs21389337",297,{"v":3.4e-80,"d":"3.40E-80"},"KOG3075","Ribose 5-phosphate isomerase",null,"G","Carbohydrate transport and metabolism","METABOLISM","K01807|1|1.6e-85|320.1|sasa:106600683|ribose 5-phosphate isomerase A [EC:5.3.1.6]"]
["XP_064466458.1",null,null,"GO:0007032//endosome organization;GO:0006897//endocytosis;GO:0097494//regulation of vesicle size","GO:0003924//GTPase activity;GO:0019003//GDP binding;GO:0005525//GTP binding","GO:0015629//actin cytoskeleton;GO:0070062//extracellular exosome;GO:0045335//phagocytic vesicle;GO:0005886//plasma membrane;GO:0005769//early endosome","Hs10190714",201.8,{"v":1e-51,"d":"1.00E-51"},"KOG0092","GTPase Rab5/YPT51 and related small G protein superfamily GTPases",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K07891|1|1.3e-52|210.3|spu:585164|Ras-related protein Rab-22"]
["XP_064466539.1",9.542305551,null,"GO:0006094//gluconeogenesis","GO:0004613//phosphoenolpyruvate carboxykinase (GTP) activity;GO:0016301//kinase activity;GO:0005525//GTP binding",null,"Hs13653992",893.3,{"v":2.5e-259,"d":"2.50E-259"},"KOG3749","Phosphoenolpyruvate carboxykinase",null,"C","Energy production and conversion","METABOLISM","K01596|1|8.1e-274|946.8|aplc:110980089|phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]"]
["XP_064466665.1",null,null,"GO:0070972//protein localization to endoplasmic reticulum","GO:0033149//FFAT motif binding","GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","Hs4759302",217.6,{"v":2.2e-56,"d":"2.20E-56"},"KOG0439","VAMP-associated protein involved in inositol metabolism",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K10707|1|6.7e-85|317.8|isc:IscW_ISCW022270|vesicle-associated membrane protein-associated protein B!K06096|2|4.7e-62|241.9|lgi:LOTGIDRAFT_232132|vesicle-associated membrane protein-associated protein A"]
["XP_064467181.1",null,null,"GO:0006301//postreplication repair;GO:0070534//protein K63-linked ubiquitination","GO:0031625//ubiquitin protein ligase binding;GO:0016874//ligase activity;GO:0061630//ubiquitin protein ligase activity","GO:0005737//cytoplasm;GO:0005634//nucleus",7295469,222.6,{"v":4.3e-58,"d":"4.30E-58"},"KOG0896","Ubiquitin-conjugating enzyme E2",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K10704|1|1.8e-67|259.2|dpte:113791391|ubiquitin-conjugating enzyme E2 variant"]
["XP_064467334.1",{"$nulls":3},"GO:0047880//erythrulose reductase activity;GO:0016491//oxidoreductase activity",null,"Hs7705925",261.9,{"v":1.1e-69,"d":"1.10E-69"},"KOG1207","Diacetyl reductase/L-xylulose reductase",null,"Q","Secondary metabolites biosynthesis, transport and catabolism","METABOLISM","K03331|1|5.1e-99|364.8|isc:IscW_ISCW020246|L-xylulose reductase [EC:1.1.1.10]"]
["XP_064467414.1",8.068863294,{"$nulls":4},7304169,782.3,{"v":1.3e-225,"d":"1.30E-225"},"KOG4242","Predicted myosin-I-binding protein",null,"N","Cell motility","CELLULAR PROCESSES AND SIGNALING","K20493|1|0.0e+00|1185.2|zne:110833737|leucine-rich repeat-containing protein 16"]
["XP_064470514.1",null,null,"GO:0042462//eye photoreceptor cell development;GO:0036060//slit diaphragm assembly;GO:0060271//cilium assembly;GO:0072015//glomerular visceral epithelial cell development;GO:0045197//establishment or maintenance of epithelial cell apical/basal polarity;GO:0003094//glomerular filtration;GO:0048793//pronephros development;GO:0060042//retina morphogenesis in camera-type eye;GO:0072104//glomerular capillary formation;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules","GO:0005509//calcium ion binding","GO:0043234//protein complex;GO:0016021//integral component of membrane;GO:0005886//plasma membrane",7290390,59.7,{"v":2.1e-08,"d":"2.10E-08"},"KOG1217","Fibrillins and related proteins containing Ca2+-binding EGF-like domains",null,"T","Signal transduction mechanisms","CELLULAR PROCESSES AND SIGNALING","K02599|1|2.3e-10|71.6|aplc:110982290|Notch 1"]
["XP_064470684.1",8.605879173,null,"GO:0006360//transcription from RNA polymerase I promoter;GO:0006351//transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter;GO:0006383//transcription from RNA polymerase III promoter",null,"GO:0005736//DNA-directed RNA polymerase I complex;GO:0005666//DNA-directed RNA polymerase III complex;GO:0005665//DNA-directed RNA polymerase II, core complex","Hs14589953",258.5,{"v":7.1e-69,"d":"7.10E-69"},"KOG3400","RNA polymerase subunit 8",null,"K","Transcription","INFORMATION STORAGE AND PROCESSING","K03016|1|4.3e-69|264.6|crg:105330854|DNA-directed RNA polymerases I, II, and III subunit RPABC3"]
["XP_064470982.1",null,9.706323465,"GO:0019991//septate junction assembly",null,"GO:0016021//integral component of membrane;GO:0005918//septate junction",7303450,386.7,{"v":4.2e-107,"d":"4.20E-107"},"KOG3510","FOG: Immunoglobulin C-2 Type/fibronectin type III domains",null,"T","Signal transduction mechanisms","CELLULAR PROCESSES AND SIGNALING","K06772|1|3.9e-31|139.8|lgi:LOTGIDRAFT_125059|limbic system-associated membrane protein!K17341|2|3.2e-25|120.2|myi:110461561|hemicentin"]
["XP_064471380.1",null,8.564243944,"GO:0006355//regulation of transcription, DNA-templated;GO:0006457//protein folding","GO:0051082//unfolded protein binding","GO:0005737//cytoplasm;GO:0016272//prefoldin complex","Hs4505743",133.3,{"v":3.7e-31,"d":"3.70E-31"},"KOG3048","Molecular chaperone Prefoldin, subunit 5",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K04797|1|1.2e-56|223.4|isc:IscW_ISCW022328|prefoldin alpha subunit"]
["XP_064471622.1",10.34960455,null,"GO:0006457//protein folding;GO:0009408//response to heat","GO:0031072//heat shock protein binding;GO:0051082//unfolded protein binding;GO:0046872//metal ion binding;GO:0005524//ATP binding","GO:0005829//cytosol","Hs4504511",567.4,{"v":1.9e-161,"d":"1.90E-161"},"KOG0712","Molecular chaperone (DnaJ superfamily)",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K09502|1|2.1e-190|669.1|isc:IscW_ISCW013384|DnaJ homolog subfamily A member 1"]
["XP_064471871.1",{"$nulls":5},7301622,763.1,{"v":5e-220,"d":"5.00E-220"},"KOG2220","Predicted signal transduction protein",null,"R","General function prediction only","POORLY CHARACTERIZED","K12200|1|4.7e-266|921.4|isc:IscW_ISCW019764|programmed cell death 6-interacting protein"]
["XP_064472400.1",{"$nulls":3},"GO:0004518//nuclease activity;GO:0008270//zinc ion binding;GO:0003677//DNA binding",{"$nulls":10},"K19410|1|1.6e-19|101.7|dpa:109543998|inner nuclear membrane protein Man1!K06676|2|5.9e-06|56.6|bfo:BRAFLDRAFT_124950|condensin complex subunit 2"]
["XP_064472986.1",null,null,"GO:0006897//endocytosis;GO:0016050//vesicle organization","GO:0035091//phosphatidylinositol binding","GO:0005768//endosome;GO:0019898//extrinsic component of membrane",7299654,276.6,{"v":2.8e-74,"d":"2.80E-74"},"KOG2527","Sorting nexin SNX11",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K17918|1|8.6e-87|323.6|isc:IscW_ISCW000499|sorting nexin-3/12"]
["XP_064472987.1",10.40813991,{"$nulls":3},"GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum","Hs5454090",142.9,{"v":5e-34,"d":"5.00E-34"},"KOG4088","Translocon-associated complex TRAP, delta subunit",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K04571|1|1.4e-50|203.4|isc:IscW_ISCW010675|translocon-associated protein subunit delta"]
["XP_064473098.1",null,null,"GO:0030036//actin cytoskeleton organization","GO:0003779//actin binding","GO:0005856//cytoskeleton",7297792,401.4,{"v":2.7e-111,"d":"2.70E-111"},"KOG1830","Wiskott Aldrich syndrome proteins",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K06220|1|2.2e-132|476.9|tca:662022|WAS protein family"]
["XP_064473305.1",null,null,"GO:0007015//actin filament organization","GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding",null,"Hs7382496",454.5,{"v":2.1e-127,"d":"2.10E-127"},"KOG0578","p21-activated serine/threonine protein kinase",null,"T","Signal transduction mechanisms","CELLULAR PROCESSES AND SIGNALING","K04409|1|1.8e-134|483.4|lak:106153444|p21-activated kinase 1 [EC:2.7.11.1]!K05733|4|2.5e-128|463.0|crg:105329587|p21-activated kinase 3 [EC:2.7.11.1]"]
["XP_064474883.1",9.592420266,null,null,"GO:0003746//translation elongation factor activity;GO:0003924//GTPase activity;GO:0005525//GTP binding",null,7302127,1435.2,0,"KOG0469","Elongation factor 2",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K03234|1|0.0e+00|1541.6|dpte:113789989|elongation factor 2"]
["XP_064475140.1",{"$nulls":3},"GO:0003723//RNA binding",null,"Hs13775188",79.3,{"v":6e-14,"d":"6.00E-14"},"KOG2039","Transcriptional coactivator p100",null,"K","Transcription","INFORMATION STORAGE AND PROCESSING","K18405|1|7.2e-63|247.3|isc:IscW_ISCW011035|tudor domain-containing protein 1/4/6/7"]
["XP_064475899.1",null,10.21123128,"GO:0006004//fucose metabolic process","GO:0004560//alpha-L-fucosidase activity","GO:0016021//integral component of membrane","Hs4503803",459.5,{"v":6.2e-129,"d":"6.20E-129"},"KOG3340","Alpha-L-fucosidase",null,"G","Carbohydrate transport and metabolism","METABOLISM","K01206|1|2.4e-144|516.2|isc:IscW_ISCW012070|alpha-L-fucosidase [EC:3.2.1.51]"]
["XP_064476695.1",9.110395382,null,"GO:0007165//signal transduction","GO:0003924//GTPase activity;GO:0005525//GTP binding","GO:0016020//membrane","Hs15718761",315.8,{"v":4.8e-86,"d":"4.80E-86"},"KOG0395","Ras-related GTPase",null,"R","General function prediction only","POORLY CHARACTERIZED","K07827|1|2.3e-91|339.0|tut:107360380|GTPase KRas"]
["XP_064476971.1",8.479727421,null,"GO:0006508//proteolysis","GO:0008239//dipeptidyl-peptidase activity;GO:0004180//carboxypeptidase activity;GO:0008236//serine-type peptidase activity",null,"Hs4826940",459.5,{"v":6.7e-129,"d":"6.70E-129"},"KOG2183","Prolylcarboxypeptidase (angiotensinase C)",null,"OR","Posttranslational modification, protein turnover, chaperones;General function prediction only","CELLULAR PROCESSES AND SIGNALING;POORLY CHARACTERIZED","K01285|1|2.6e-152|542.7|isc:IscW_ISCW003037|lysosomal Pro-X carboxypeptidase [EC:3.4.16.2]"]
["XP_064476998.1",null,null,"GO:0015991//ATP hydrolysis coupled proton transport","GO:0046961//proton-transporting ATPase activity, rotational mechanism;GO:0008553//hydrogen-exporting ATPase activity, phosphorylative mechanism;GO:0015078//hydrogen ion transmembrane transporter activity","GO:0033180//proton-transporting V-type ATPase, V1 domain;GO:0005765//lysosomal membrane;GO:0000221//vacuolar proton-transporting V-type ATPase, V1 domain",7302940,549.3,{"v":5.2e-156,"d":"5.20E-156"},"KOG2909","Vacuolar H+-ATPase V1 sector, subunit C",null,"C","Energy production and conversion","METABOLISM","K02148|1|9.1e-188|660.2|isc:IscW_ISCW009268|V-type H+-transporting ATPase subunit C"]
["XP_064477204.1",8.435268502,{"$nulls":4},"Hs15295671",250.4,{"v":3.7e-66,"d":"3.70E-66"},"KOG0553","TPR repeat-containing protein",null,"R","General function prediction only","POORLY CHARACTERIZED","K16365|1|1.1e-89|334.0|isc:IscW_ISCW010489|small glutamine-rich tetratricopeptide repeat-containing protein alpha"]
["XP_064477265.1",9.178432527,{"$nulls":4},7304084,367.1,{"v":3.4e-101,"d":"3.40E-101"},"KOG3938","RGS-GAIP interacting protein GIPC, contains PDZ domain",null,"TU","Signal transduction mechanisms;Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING;CELLULAR PROCESSES AND SIGNALING","K20056|1|6.0e-154|547.7|isc:IscW_ISCW015960|PDZ domain-containing protein GIPC"]
["XP_064477344.1",8.784571971,{"$nulls":4},"Hs4502923",157.5,{"v":2.3e-38,"d":"2.30E-38"},"KOG2046","Calponin",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K20526|1|8.1e-87|323.9|isc:IscW_ISCW003081|transgelin"]
["XP_064477929.1",9.099747125,null,"GO:0000183//chromatin silencing at rDNA;GO:0032776//DNA methylation on cytosine;GO:0030307//positive regulation of cell growth;GO:0008584//male gonad development;GO:0035264//multicellular organism growth;GO:0044267//cellular protein metabolic process;GO:0001649//osteoblast differentiation;GO:1902036//regulation of hematopoietic stem cell differentiation;GO:0007140//male meiotic nuclear division;GO:0045814//negative regulation of gene expression, epigenetic;GO:0045815//positive regulation of gene expression, epigenetic;GO:0048477//oogenesis;GO:0090230//regulation of centromere complex assembly;GO:0007596//blood coagulation;GO:0031509//telomeric heterochromatin assembly;GO:0008283//cell proliferation;GO:1902340//negative regulation of chromosome condensation;GO:0007283//spermatogenesis;GO:0060964//regulation of gene silencing by miRNA;GO:0007338//single fertilization;GO:0007286//spermatid development;GO:0045652//regulation of megakaryocyte differentiation;GO:0006997//nucleus organization;GO:0042692//muscle cell differentiation;GO:0007420//brain development;GO:0006336//DNA replication-independent nucleosome assembly;GO:0009725//response to hormone;GO:0006334//nucleosome assembly;GO:0031508//pericentric heterochromatin assembly;GO:0032200//telomere organization;GO:0007566//embryo implantation","GO:0042393//histone binding;GO:0031492//nucleosomal DNA binding;GO:0003677//DNA binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0046982//protein heterodimerization activity;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding","GO:0000786//nucleosome;GO:0000784//nuclear chromosome, telomeric region;GO:0000788//nuclear nucleosome;GO:0000228//nuclear chromosome;GO:0001740//Barr body;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0043234//protein complex;GO:0005700//polytene chromosome;GO:0005576//extracellular region","Hs4504279",265,{"v":7e-71,"d":"7.00E-71"},"KOG1745","Histones H3 and H4",null,"B","Chromatin structure and dynamics","INFORMATION STORAGE AND PROCESSING","K11253|1|3.0e-69|265.0|pcf:106794049|histone H3"]
["XP_064478244.1",null,null,"GO:0006004//fucose metabolic process","GO:0004560//alpha-L-fucosidase activity","GO:0016021//integral component of membrane","Hs4503803",574.3,{"v":1.8e-163,"d":"1.80E-163"},"KOG3340","Alpha-L-fucosidase",null,"G","Carbohydrate transport and metabolism","METABOLISM","K01206|1|3.4e-186|655.2|isc:IscW_ISCW012070|alpha-L-fucosidase [EC:3.2.1.51]"]
["XP_064478476.1",{"$nulls":3},"GO:0016491//oxidoreductase activity",null,"Hs10337605",284.6,{"v":1.8e-76,"d":"1.80E-76"},"KOG0725","Reductases with broad range of substrate specificities",null,"R","General function prediction only","POORLY CHARACTERIZED","K11147|1|2.5e-89|332.8|tut:107365995|dehydrogenase/reductase SDR family member 4 [EC:1.1.-.-]"]
["XP_064478582.1",null,10.15272428,"GO:0006457//protein folding;GO:1902175//regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:0019511//peptidyl-proline hydroxylation;GO:0045454//cell redox homeostasis;GO:0034976//response to endoplasmic reticulum stress","GO:0003756//protein disulfide isomerase activity;GO:0016757//transferase activity, transferring glycosyl groups","GO:0005783//endoplasmic reticulum",7294310,569.3,{"v":6.3e-162,"d":"6.30E-162"},"KOG0190","Protein disulfide isomerase (prolyl 4-hydroxylase beta subunit)",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K09580|1|3.9e-207|724.9|isc:IscW_ISCW010827|protein disulfide-isomerase A1 [EC:5.3.4.1]"]
["XP_064478692.1",{"$nulls":4},"GO:0016021//integral component of membrane",7301370,79.7,{"v":1.8e-13,"d":"1.80E-13"},"KOG1215","Low-density lipoprotein receptors containing Ca2+-binding EGF-like domains",null,"T","Signal transduction mechanisms","CELLULAR PROCESSES AND SIGNALING","K22453|1|2.8e-190|672.5|nve:NEMVE_v1g239043|trefoil factor 2"]
["XP_064479578.1",{"$nulls":4},"GO:0016021//integral component of membrane"]
["XP_064480241.1",null,null,"GO:0042254//ribosome biogenesis","GO:0016829//lyase activity","GO:0005840//ribosome",7296522,458.8,{"v":7.7e-129,"d":"7.70E-129"},"KOG0815","60S acidic ribosomal protein P0",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K02941|1|4.9e-163|577.8|isc:IscW_ISCW007303|large subunit ribosomal protein LP0"]
["XP_064480368.1",null,null,"GO:0030154//cell differentiation;GO:0010265//SCF complex assembly;GO:0043086//negative regulation of catalytic activity;GO:0016567//protein ubiquitination",null,"GO:0005794//Golgi apparatus;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0016020//membrane;GO:0005654//nucleoplasm;GO:0031461//cullin-RING ubiquitin ligase complex;GO:0005829//cytosol","HsM8924260",1645.2,0,"KOG1824","TATA-binding protein-interacting protein",null,"R","General function prediction only","POORLY CHARACTERIZED","K17263|1|0.0e+00|1718.0|lak:106167662|cullin-associated NEDD8-dissociated protein 1"]
["XP_064481739.1",null,null,"GO:0006096//glycolytic process","GO:0004618//phosphoglycerate kinase activity;GO:0005524//ATP binding",null,"Hs4505763",602.4,{"v":5.6e-172,"d":"5.60E-172"},"KOG1367","3-phosphoglycerate kinase",null,"G","Carbohydrate transport and metabolism","METABOLISM","K00927|1|2.5e-191|672.2|isc:IscW_ISCW015616|phosphoglycerate kinase [EC:2.7.2.3]"]
["XP_064482108.1",null,null,"GO:0042904//9-cis-retinoic acid biosynthetic process;GO:0042574//retinal metabolic process","GO:0001758//retinal dehydrogenase activity;GO:0016491//oxidoreductase activity","GO:0070062//extracellular exosome;GO:0005622//intracellular","Hs12007648",574.3,{"v":1.9e-163,"d":"1.90E-163"},"KOG2450","Aldehyde dehydrogenase",null,"C","Energy production and conversion","METABOLISM","K00149|1|1.3e-95|354.4|tup:102490252|aldehyde dehydrogenase family 9 member A1 [EC:1.2.1.47 1.2.1.3]"]
["XP_064483498.1",null,null,"GO:0006338//chromatin remodeling;GO:0019303//D-ribose catabolic process;GO:0009191//ribonucleoside diphosphate catabolic process;GO:1990966//ATP generation from poly-ADP-D-ribose","GO:0016787//hydrolase activity;GO:0016779//nucleotidyltransferase activity;GO:0019144//ADP-sugar diphosphatase activity;GO:0044715//8-oxo-dGDP phosphatase activity;GO:0000287//magnesium ion binding;GO:0047631//ADP-ribose diphosphatase activity;GO:0030515//snoRNA binding;GO:0042803//protein homodimerization activity","GO:0070062//extracellular exosome;GO:0005634//nucleus","Hs7657403",140.6,{"v":3.5e-33,"d":"3.50E-33"},"KOG3041","Nucleoside diphosphate-sugar hydrolase of the MutT (NUDIX) family",null,"L","Replication, recombination and repair","INFORMATION STORAGE AND PROCESSING","K13987|1|1.9e-90|336.3|isc:IscW_ISCW021976|ADP-sugar pyrophosphatase / 8-oxo-dGDP phosphatase / ADP-D-ribose pyrophosphorylase [EC:3.6.1.13 3.6.1.58 3.6.1.- 2.7.7.96]"]
["XP_064483887.1",10.42543063,{"$nulls":4},7294858,746.5,{"v":4.2e-215,"d":"4.20E-215"},"KOG0045","Cytosolic Ca2+-dependent cysteine protease (calpain), large subunit (EF-Hand protein superfamily)",null,"OT","Posttranslational modification, protein turnover, chaperones;Signal transduction mechanisms","CELLULAR PROCESSES AND SIGNALING;CELLULAR PROCESSES AND SIGNALING","K08585|1|2.9e-243|845.5|bim:100747565|calpain, invertebrate [EC:3.4.22.-]"]
["XP_064484384.1",9.819437289,{"$nulls":3},"GO:0016020//membrane",7298546,429.9,{"v":3.3e-120,"d":"3.30E-120"},"KOG3083","Prohibitin",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K17080|1|5.9e-125|451.1|tnl:113501490|prohibitin 1"]
["XP_064484842.1",9.684172436,null,"GO:0048873//homeostasis of number of cells within a tissue;GO:0006099//tricarboxylic acid cycle;GO:0006106//fumarate metabolic process;GO:0006108//malate metabolic process","GO:0004333//fumarate hydratase activity","GO:0070062//extracellular exosome;GO:0005739//mitochondrion;GO:0045239//tricarboxylic acid cycle enzyme complex","Hs19743875",748,{"v":9.5e-216,"d":"9.50E-216"},"KOG1317","Fumarase",null,"C","Energy production and conversion","METABOLISM","K01679|1|1.4e-217|759.6|dpx:DAPPUDRAFT_46417|fumarate hydratase, class II [EC:4.2.1.2]"]
["XP_064484884.1",8.175514647,{"$nulls":4},7294024,750.4,{"v":2.7e-216,"d":"2.70E-216"},"KOG3727","Mitogen inducible gene product (contains ERM and PH domains)",null,"D","Cell cycle control, cell division, chromosome partitioning","CELLULAR PROCESSES AND SIGNALING","K17083|1|0.0e+00|1142.1|isc:IscW_ISCW011051|kindlin 2"]
["XP_064486428.1",null,null,"GO:0015986//ATP synthesis coupled proton transport","GO:0005524//ATP binding;GO:0046933//proton-transporting ATP synthase activity, rotational mechanism","GO:0045261//proton-transporting ATP synthase complex, catalytic core F(1)","Hs4757810",850.9,{"v":1.2e-246,"d":"1.20E-246"},"KOG1353","F0F1-type ATP synthase, alpha subunit",null,"C","Energy production and conversion","METABOLISM","K02132|1|9.2e-274|946.4|isc:IscW_ISCW011988|F-type H+-transporting ATPase subunit alpha"]
["XP_064486435.1",8.933225692,null,"GO:0040017//positive regulation of locomotion;GO:0090254//cell elongation involved in imaginal disc-derived wing morphogenesis;GO:0050770//regulation of axonogenesis;GO:0030589//pseudocleavage involved in syncytial blastoderm formation;GO:0030241//skeletal muscle myosin thick filament assembly;GO:0014057//positive regulation of acetylcholine secretion, neurotransmission;GO:0045199//maintenance of epithelial cell apical/basal polarity;GO:0030036//actin cytoskeleton organization;GO:0034334//adherens junction maintenance;GO:0008045//motor neuron axon guidance;GO:0070593//dendrite self-avoidance;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0007298//border follicle cell migration;GO:0001745//compound eye morphogenesis;GO:0035317//imaginal disc-derived wing hair organization;GO:0007435//salivary gland morphogenesis;GO:1901739//regulation of myoblast fusion;GO:0030950//establishment or maintenance of actin cytoskeleton polarity;GO:0031532//actin cytoskeleton reorganization;GO:0007368//determination of left/right symmetry;GO:0007480//imaginal disc-derived leg morphogenesis;GO:0007349//cellularization;GO:1904059//regulation of locomotor rhythm;GO:0051493//regulation of cytoskeleton organization;GO:0051017//actin filament bundle assembly;GO:0016476//regulation of embryonic cell shape;GO:0046663//dorsal closure, leading edge cell differentiation;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0030334//regulation of cell migration;GO:0007370//ventral furrow formation;GO:0035159//regulation of tube length, open tracheal system;GO:0032970//regulation of actin filament-based process;GO:0042060//wound healing;GO:0006974//cellular response to DNA damage stimulus;GO:0042335//cuticle development;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0035277//spiracle morphogenesis, open tracheal system;GO:0035298//regulation of Malpighian tubule size;GO:0007405//neuroblast proliferation;GO:0007264//small GTPase mediated signal transduction;GO:0008347//glial cell migration;GO:0007374//posterior midgut invagination;GO:0035099//hemocyte migration;GO:0007015//actin filament organization;GO:0035149//lumen formation, open tracheal system;GO:0042249//establishment of planar polarity of embryonic epithelium;GO:0006897//endocytosis;GO:0000915//actomyosin contractile ring assembly;GO:0007377//germ-band extension;GO:0007422//peripheral nervous system development;GO:0007395//dorsal closure, spreading of leading edge cells;GO:0051489//regulation of filopodium assembly;GO:0090251//protein localization involved in establishment of planar polarity;GO:0090303//positive regulation of wound healing;GO:1903475//mitotic actomyosin contractile ring assembly;GO:0032456//endocytic recycling;GO:0045184//establishment of protein localization;GO:0035006//melanization defense response;GO:0070252//actin-mediated cell contraction;GO:0071896//protein localization to adherens junction","GO:0019901//protein kinase binding;GO:0032794//GTPase activating protein binding;GO:0003779//actin binding;GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0019900//kinase binding","GO:0016020//membrane;GO:0070451//cell hair;GO:0045179//apical cortex;GO:0016324//apical plasma membrane;GO:0044291//cell-cell contact zone;GO:0032154//cleavage furrow;GO:0005938//cell cortex;GO:0005622//intracellular",7302996,212.2,{"v":7.7e-55,"d":"7.70E-55"},"KOG0393","Ras-related small GTPase, Rho type",null,"R","General function prediction only","POORLY CHARACTERIZED","K04513|1|2.6e-53|212.6|tca:663337|Ras homolog gene family, member A"]
["XP_064486497.1",{"$nulls":3},"GO:0005509//calcium ion binding;GO:0016174//NAD(P)H oxidase activity",null,7293714,240,{"v":3.4e-63,"d":"3.40E-63"},"KOG0044","Ca2+ sensor (EF-Hand superfamily)",null,"T","Signal transduction mechanisms","CELLULAR PROCESSES AND SIGNALING","K19695|1|8.9e-43|177.6|cmk:103172717|neurocalcin delta"]
["XP_064486521.1",{"$nulls":5},7292277,848.2,{"v":7.4e-246,"d":"7.40E-246"},"KOG1370","S-adenosylhomocysteine hydrolase",null,"H","Coenzyme transport and metabolism","METABOLISM","K01251|1|2.3e-250|868.6|zne:110834591|adenosylhomocysteinase [EC:3.3.1.1]"]
["XP_064486588.1",9.773360965,null,null,"GO:0004177//aminopeptidase activity;GO:0030145//manganese ion binding",null,"Hs18590513",611.3,{"v":1.5e-174,"d":"1.50E-174"},"KOG2737","Putative metallopeptidase",null,"R","General function prediction only","POORLY CHARACTERIZED","K14213|1|3.5e-182|642.1|tut:107369298|Xaa-Pro dipeptidase [EC:3.4.13.9]"]
["XP_064488685.1",null,null,"GO:0015992//proton transport;GO:0006740//NADPH regeneration","GO:0050661//NADP binding;GO:0051287//NAD binding;GO:0008746//NAD(P)+ transhydrogenase activity;GO:0008750//NAD(P)+ transhydrogenase (AB-specific) activity","GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane",{"$nulls":9},"K00323|1|0.0e+00|1554.3|dpx:DAPPUDRAFT_315656|H+-translocating NAD(P) transhydrogenase [EC:1.6.1.2 7.1.1.1]"]
["XP_064488945.1",null,null,"GO:0006511//ubiquitin-dependent protein catabolic process","GO:0004298//threonine-type endopeptidase activity","GO:0005737//cytoplasm;GO:0019773//proteasome core complex, alpha-subunit complex;GO:0005634//nucleus","Hs4506179",379.4,{"v":5.2e-105,"d":"5.20E-105"},"KOG0863","20S proteasome, regulatory subunit alpha type PSMA1/PRE5",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K02725|1|4.5e-112|408.3|zne:110826834|20S proteasome subunit alpha 6 [EC:3.4.25.1]"]
["XP_064489032.1",null,11.01389586,{"$nulls":3},7293656,321.2,{"v":1.1e-86,"d":"1.10E-86"},"KOG1810","Cell cycle-associated protein",null,"D","Cell cycle control, cell division, chromosome partitioning","CELLULAR PROCESSES AND SIGNALING"]
["XP_064489042.1",{"$nulls":3},"GO:0003924//GTPase activity;GO:0005525//GTP binding",null,"Hs4503507",802.4,{"v":4.2e-232,"d":"4.20E-232"},"KOG0466","Translation initiation factor 2, gamma subunit (eIF-2gamma; GTPase)",null,"J","Translation, ribosomal structure and biogenesis","INFORMATION STORAGE AND PROCESSING","K03242|1|1.5e-237|825.9|bfo:BRAFLDRAFT_125911|translation initiation factor 2 subunit 3"]
["XP_064489463.1",null,null,"GO:0006108//malate metabolic process;GO:0006090//pyruvate metabolic process","GO:0046872//metal ion binding;GO:0004473//malate dehydrogenase (decarboxylating) (NADP+) activity;GO:0051287//NAD binding;GO:0004471//malate dehydrogenase (decarboxylating) (NAD+) activity","GO:0005739//mitochondrion;GO:0016021//integral component of membrane",7301553,621.7,{"v":1.2e-177,"d":"1.20E-177"},"KOG1257","NADP+-dependent malic enzyme",null,"C","Energy production and conversion","METABOLISM","K00029|1|5.3e-242|840.9|isc:IscW_ISCW011260|malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40]"]
["XP_064489583.1",10.38975263,null,"GO:0007165//signal transduction;GO:0015991//ATP hydrolysis coupled proton transport","GO:0046961//proton-transporting ATPase activity, rotational mechanism","GO:0033178//proton-transporting two-sector ATPase complex, catalytic domain",7296718,258.5,{"v":1.1e-68,"d":"1.10E-68"},"KOG1664","Vacuolar H+-ATPase V1 sector, subunit E",null,"C","Energy production and conversion","METABOLISM","K20641|1|1.2e-75|287.0|isc:IscW_ISCW001551|Rho GTPase-activating protein 20!K02150|2|5.6e-73|278.1|dpl:KGM_204676|V-type H+-transporting ATPase subunit E"]
["XP_064489889.1",9.150312645,null,"GO:0030163//protein catabolic process","GO:0008233//peptidase activity;GO:0005524//ATP binding;GO:0036402//proteasome-activating ATPase activity","GO:0005737//cytoplasm",7301070,805.8,{"v":3.6e-233,"d":"3.60E-233"},"KOG0726","26S proteasome regulatory complex, ATPase RPT2",null,"O","Posttranslational modification, protein turnover, chaperones","CELLULAR PROCESSES AND SIGNALING","K03062|1|3.9e-235|817.8|pcf:106787932|26S proteasome regulatory subunit T2"]
["XP_064489898.1",{"$nulls":3},"GO:0016491//oxidoreductase activity",null,"Hs4758912",304.7,{"v":2.1e-82,"d":"2.10E-82"},"KOG1198","Zinc-binding oxidoreductase",null,"CR","Energy production and conversion;General function prediction only","METABOLISM;POORLY CHARACTERIZED","K10133|1|3.5e-101|372.5|lak:106168888|tumor protein p53-inducible protein 3 [EC:1.-.-.-]"]
["XP_064490030.1",9.786828893,null,"GO:0006886//intracellular protein transport;GO:0061025//membrane fusion;GO:0035494//SNARE complex disassembly","GO:0019905//syntaxin binding;GO:0005483//soluble NSF attachment protein activity","GO:0005774//vacuolar membrane;GO:0005622//intracellular;GO:0031201//SNARE complex",7293665,429.9,{"v":3.5e-120,"d":"3.50E-120"},"KOG1586","Protein required for fusion of vesicles in vesicular transport, alpha-SNAP",null,"U","Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING","K15296|1|4.2e-129|464.9|phu:Phum_PHUM600830|alpha-soluble NSF attachment protein"]
["XP_064490053.1",null,null,"GO:0006511//ubiquitin-dependent protein catabolic process","GO:0031624//ubiquitin conjugating enzyme binding;GO:0043130//ubiquitin binding","GO:0005737//cytoplasm",{"$nulls":9},"K05402|1|4.7e-78|295.4|isc:IscW_ISCW002962|toll-interacting protein"]
["XP_064490094.1",null,null,"GO:0030041//actin filament polymerization","GO:0003779//actin binding",null,"HsM7661718",104,{"v":9.5e-22,"d":"9.50E-22"},"KOG3655","Drebrins and related actin binding proteins",null,"Z","Cytoskeleton","CELLULAR PROCESSES AND SIGNALING","K06106|1|9.0e-209|730.7|isc:IscW_ISCW000141|cortactin"]
["XP_064490113.1",8.413739396,null,"GO:0034504//protein localization to nucleus;GO:0000055//ribosomal large subunit export from nucleus;GO:0000056//ribosomal small subunit export from nucleus;GO:0010824//regulation of centrosome duplication;GO:0042176//regulation of protein catabolic process;GO:0046825//regulation of protein export from nucleus;GO:0006886//intracellular protein transport","GO:0005049//nuclear export signal receptor activity;GO:0008536//Ran GTPase binding","GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0005642//annulate lamellae;GO:0005634//nucleus;GO:0031965//nuclear membrane;GO:0030529//intracellular ribonucleoprotein complex;GO:0005829//cytosol;GO:0000776//kinetochore","Hs4507943",1726.1,0,"KOG2020","Nuclear transport receptor CRM1/MSN5 (importin beta superfamily)",null,"YU","Nuclear structure;Intracellular trafficking, secretion, and vesicular transport","CELLULAR PROCESSES AND SIGNALING;CELLULAR PROCESSES AND SIGNALING","K14290|1|0.0e+00|1763.8|zne:110834350|exportin-1"]