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["Supplementary Table 5. Baseline characteristics of the 11 collected brain tumor cohorts."]
["The age information of GSE108474 is categorical and thus not shown. NA, not available."]
[{"$nulls":5},"CGGA-C","CGGA-B","PBCA-US","CGGA-D","GSE16011","TCGA-LGG","GSE108474","E-MTAB-3892","GSE85217","TCGA-GBM","GSE13041"]
["Cases",{"$nulls":4},313,657,111,285,260,512,474,152,612,167,267]
["Gender (n %)"]
[null,"Male",{"$nulls":3},"197(62.9)","374(56.9)","52(46.8)","168(58.9)","175(67.3)","284(55.5)","238(50.2)","88(57.9)","392(64.1)","108(64.7)","151(56.6)"]
[null,"Female",{"$nulls":3},"116(37.1)","283(43.1)","59(53.2)","117(41.1)","85(32.7)","228(44.5)","140(29.5)","64(42.1)","207(33.8)","59(35.3)","88(33.0)"]
[null,"Unknown",{"$nulls":3},"0(0.0)","0(0.0)","0(0.0)","0(0.0)","0(0.0)","0(0.0)","96(20.3)","0(0.0)","13(2.1)","0(0.0)","28(10.5)"]
["Age"]
[null,"Median (IQR)",{"$nulls":3},"42.0(15.0)","43.0(18.0)","6.0(8.0)","42.0(17.0)","51.6(23.7)","41.2(20.9)","NA","45.0(20.0)","8.0(7.1)","60.9(18.5)","54.0(18.0)"]
["Cancer type (n %)"]
[null,"Primary",{"$nulls":3},"222(70.9)","404(61.5)","0(0.0)","250(88.7)","0(0.0)","465(90.8)","0(0.0)","152(100.0)","612(100.0)","0(0.0)","0(0.0)"]
[null,"Recurrent",{"$nulls":3},"58(18.5)","253(38.5)","0(0.0)","21(7.4)","0(0.0)","0(0.0)","0(0.0)","0(0.0)","0(0.0)","0(0.0)","0(0.0)"]
[null,"Secondary",{"$nulls":3},"29(9.3)","0(0.0)","0(0.0)","11(3.9)","0(0.0)","0(0.0)","0(0.0)","0(0.0)","0(0.0)","0(0.0)","0(0.0)"]
[null,"Post-treatment",{"$nulls":3},"0(0.0)","0(0.0)","0(0.0)","0(0.0)","0(0.0)","0(0.0)","474(100.0)","0(0.0)","0(0.0)","0(0.0)","0(0.0)"]
[null,"Unknown",{"$nulls":3},"4(1.3)","0(0.0)","111(100.0)","3(1.1)","260(100.0)","47(9.2)","0(0.0)","0(0.0)","0(0.0)","167(100.0)","267(100.0)"]
["Grade  (n %)"]
[null,"II",{"$nulls":3},"98(31.3)","172(26.2)","0(0.0)","106(37.2)","24(9.2)","214(41.8)","86(18.1)","43(28.3)","0(0.0)","0(0.0)","0(0.0)"]
[null,"III",{"$nulls":3},"74(23.6)","248(37.7)","0(0.0)","53(18.6)","84(32.3)","241(47.1)","83(17.5)","89(58.6)","0(0.0)","0(0.0)","0(0.0)"]
[null,"IV",{"$nulls":3},"137(43.8)","237(36.1)","0(0.0)","123(43.2)","152(58.5)","0(0.0)","124(26.2)","19(12.5)","0(0.0)","167(100.0)","267(100.0)"]
[null,"Unknown",{"$nulls":3},"4(1.3)","0(0.0)","111(100.0)","3(1.1)","0(0.0)","57(11.1)","181(38.2)","1(0.7)","612(100.0)","0(0.0)","0(0.0)"]
["Histology  (n %)"]
[null,"Diffuse glioma"]
[null,null,"Astrocytoma",null,null,"112(35.8)","254(38.7)","0(0.0)","103(36.1)","29(11.2)","169(33.0)","132(27.8)","2(1.3)","0(0.0)","0(0.0)","0(0.0)"]
[null,null,"Oligodendroglioma",null,null,"60(19.2)","137(20.9)","0(0.0)","38(13.3)","51(19.6)","172(33.6)","63(13.3)","101(66.4)","0(0.0)","0(0.0)","0(0.0)"]
[null,null,"Oligoastrocytoma",null,null,"0(0.0)","29(4.4)","0(0.0)","18(6.3)","28(10.8)","114(22.3)","9(1.9)","33(21.7)","0(0.0)","0(0.0)","0(0.0)"]
[null,null,"Glioblastoma",null,null,"137(43.8)","237(36.1)","0(0.0)","123(43.2)","152(58.5)","0(0.0)","208(43.9)","15(9.9)","0(0.0)","167(100.0)","267(100.0)"]
[null,null,"Unknown",null,null,"4(1.3)","0(0.0)","59(53.2)","3(1.1)","0(0.0)","57(11.1)","62(13.1)","1(0.7)","0(0.0)","0(0.0)","0(0.0)"]
[null,"Medulloblastoma",{"$nulls":3},"0(0.0)","0(0.0)","12(10.8)","0(0.0)","0(0.0)","0(0.0)","0(0.0)","0(0.0)","612(100.0)","0(0.0)","0(0.0)"]
[null,"Others",{"$nulls":3},"0(0.0)","0(0.0)","40(36.0)","0(0.0)","0(0.0)","0(0.0)","0(0.0)","0(0.0)","0(0.0)","0(0.0)","0(0.0)"]
["Therapy (n %)"]
[null,"Chemotherapy",{"$nulls":3},"35(11.2)","59(9.0)","0(0.0)","88(30.9)","0(0.0)","0(0.0)","0(0.0)","0(0.0)","0(0.0)","2(1.2)","0(0.0)"]
[null,"Radiotherapy",{"$nulls":3},"83(26.5)","82(12.5)","0(0.0)","30(10.5)","0(0.0)","0(0.0)","0(0.0)","0(0.0)","0(0.0)","86(51.5)","0(0.0)"]
[null,"Radio-chemotherapy",{"$nulls":3},"153(48.9)","413(62.9)","0(0.0)","146(51.2)","0(0.0)","0(0.0)","0(0.0)","0(0.0)","0(0.0)","49(29.3)","0(0.0)"]
[null,"Unkown",{"$nulls":3},"42(13.4)","103(15.7)","111(100.0)","21(7.4)","260(100.0)","512(100.0)","474(100.0)","152(100.0)","612(100.0)","30(18.0)","267(100.0)"]
["Molecular alteration  (n %)"]
[null,"IDH mutation"]
[null,null,"No",null,null,"145(46.3)","276(42.0)","51(45.9)","157(55.1)","129(49.6)","94(18.4)","NA","35(23.0)","NA","148(88.6)","NA"]
[null,null,"Yes",null,null,"167(53.4)","333(50.7)","5(4.5)","127(44.6)","79(30.4)","415(81.1)","NA","116(76.3)","NA","12(7.2)","NA"]
[{"$nulls":3},"Co-deletion of 1p and 19q"]
[{"$nulls":4},"Yes","59(18.8)","112(17.0)","NA","16(5.6)","24(9.2)","166(32.4)","NA","82(53.9)","NA","0(0.0)","NA"]
[{"$nulls":4},"No","105(33.5)","192(29.2)","NA","30(10.5)","20(7.7)","249(48.6)","NA","34(22.4)","NA","9(5.4)","NA"]
[null,"MGMT methylation"]
[null,null,"Yes",null,null,"152(48.6)","304(46.3)","NA","95(33.3)","NA","422(82.4)","NA","NA","NA","55(32.9)","NA"]
[null,null,"No",null,null,"143(45.7)","218(33.2)","NA","179(62.8)","NA","90(17.6)","NA","NA","NA","73(43.7)","NA"]
["Status  (n %)"]
[null,"Alive",{"$nulls":3},"95(30.4)","263(40.0)","52(46.8)","100(35.1)","25(9.6)","387(75.6)","79(16.7)","110(72.4)","454(74.2)","32(19.2)","21(7.9)"]
[null,"Dead",{"$nulls":3},"218(69.6)","394(60.0)","59(53.2)","185(64.9)","235(90.4)","125(24.4)","395(83.3)","42(27.6)","158(25.8)","135(80.8)","246(92.1)"]
["Overall survival"]
[null,"Median survivals (95%CI)",{"$nulls":3},"30.7(22.6 - 37.4)","35.2(29.8 - 45.2)","38.5(26.5 - 83.7)","37.4(25.8 - 51.7)","14.6(12.7 - 18.6)","88.7(68.4 - 115.7)","21.9(19.3 - 27.1)","76.0(61.0 - NA)","180.0(159.5 - NA)","13.5(12.5 - 15.3)","12.1(10.7 - 13.5)"]
["Family history of cancer (n %)"]
[null,"Yes",{"$nulls":3},"NA","NA","33(29.7)","NA","NA","87(17.0)","NA","NA","NA","NA","NA"]
[null,"No",{"$nulls":3},"NA","NA","37(33.3)","NA","NA","110(21.5)","NA","NA","NA","NA","NA"]
["KPS",{"$nulls":4},"NA","NA","NA","NA","81.2(62.2 - 100.2)","86.3(74.3 - 98.2)","78.6(57.2 - 100.1)","NA","NA","NA","NA"]
["Laterality (n %)"]
[null,"Left",{"$nulls":3},"NA","NA","NA","NA","NA","136(26.6)","NA","NA","NA","NA","NA"]
[null,"Midline",{"$nulls":3},"NA","NA","NA","NA","NA","5(1.0)","NA","NA","NA","NA","NA"]
[null,"Right",{"$nulls":3},"NA","NA","NA","NA","NA","143(27.9)","NA","NA","NA","NA","NA"]
["Tumor location (n %)"]
[null,"Posterior fossa, cerebellum",{"$nulls":3},"NA","NA","NA","NA","NA","1(0.2)","NA","NA","NA","NA","NA"]
[null,"Supratentorial, frontal lobe",{"$nulls":3},"NA","NA","NA","NA","NA","177(34.6)","NA","NA","NA","NA","NA"]
[null,"Supratentorial, not otherwise",{"$nulls":3},"NA","NA","NA","NA","NA","5(1.0)","NA","NA","NA","NA","NA"]
[null,"Supratentorial, occipital lobe",{"$nulls":3},"NA","NA","NA","NA","NA","3(0.6)","NA","NA","NA","NA","NA"]
[null,"Supratentorial, parietal lobe",{"$nulls":3},"NA","NA","NA","NA","NA","23(4.5)","NA","NA","NA","NA","NA"]
[null,"Supratentorial, temporal lobe",{"$nulls":3},"NA","NA","NA","NA","NA","78(15.2)","NA","NA","NA","NA","NA"]
["Supratentorial localization (n %)"]
[null,"Cerebral cortex",{"$nulls":3},"NA","NA","NA","NA","NA","69(13.5)","NA","NA","NA","NA","NA"]
[null,"White matter",{"$nulls":3},"NA","NA","NA","NA","NA","79(15.4)","NA","NA","NA","NA","NA"]
[null,"Deep gray (e.g.basal ganglia, thalamus)",{"$nulls":3},"NA","NA","NA","NA","NA","2(0.4)","NA","NA","NA","NA","NA"]
["Headache history (n %)"]
[null,"Yes",{"$nulls":3},"NA","NA","NA","NA","NA","107(20.9)","NA","NA","NA","NA","NA"]
[null,"No",{"$nulls":3},"NA","NA","NA","NA","NA","149(29.1)","NA","NA","NA","NA","NA"]
["Mental status changes (n %)"]
[null,"Yes",{"$nulls":3},"NA","NA","NA","NA","NA","66(12.9)","NA","NA","NA","NA","NA"]
[null,"No",{"$nulls":3},"NA","NA","NA","NA","NA","185(36.1)","NA","NA","NA","NA","NA"]
["Visual changes (n %)"]
[null,"Yes",{"$nulls":3},"NA","NA","NA","NA","NA","39(7.6)","NA","NA","NA","NA","NA"]
[null,"No",{"$nulls":3},"NA","NA","NA","NA","NA","211(41.2)","NA","NA","NA","NA","NA"]
["Sensory changes (n %)"]
[null,"Yes",{"$nulls":3},"NA","NA","NA","NA","NA","36(7.0)","NA","NA","NA","NA","NA"]
[null,"No",{"$nulls":3},"NA","NA","NA","NA","NA","212(41.4)","NA","NA","NA","NA","NA"]
["Motor movement changes (n %)"]
[null,"Yes",{"$nulls":3},"NA","NA","NA","NA","NA","63(12.3)","NA","NA","NA","NA","NA"]
[null,"No",{"$nulls":3},"NA","NA","NA","NA","NA","187(36.5)","NA","NA","NA","NA","NA"]
["Necrosis (n %)"]
[null,"Yes",{"$nulls":3},"NA","NA","NA","NA","NA","NA","NA","36(23.7)","NA","NA","NA"]
[null,"No",{"$nulls":3},"NA","NA","NA","NA","NA","NA","NA","107(70.4)","NA","NA","NA"]
["Micorvascular proliferation (n %)"]
[null,"Yes",{"$nulls":3},"NA","NA","NA","NA","NA","NA","NA","92(60.5)","NA","NA","NA"]
[null,"No",{"$nulls":3},"NA","NA","NA","NA","NA","NA","NA","50(32.9)","NA","NA","NA"]
["Seizure (n %)"]
[null,"Yes",{"$nulls":3},"NA","NA","NA","NA","NA","172(33.6)","NA","74(48.7)","NA","NA","NA"]
[null,"No",{"$nulls":3},"NA","NA","NA","NA","NA","97(18.9)","NA","42(27.6)","NA","NA","NA"]
["Relapse (n %)"]
[null,"Local recurrence",{"$nulls":3},"NA","NA","48(43.2)","NA","NA","NA","NA","NA","NA","NA","NA"]
[null,"Distant metastasis and/or local recurrence",{"$nulls":3},"NA","NA","23(20.7)","NA","NA","NA","NA","NA","NA","NA","NA"]