{"text_format":"3","workbook":"xls","n_sheets":3,"sheets":["Feuil1","Feuil2","Feuil3"],"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"Feuil1","index":0,"n_rows":35,"n_cols":12,"rows_kept":35,"merged":[[1,4,1,5],[2,4,2,5],[3,4,3,5],[4,4,4,5],[5,4,5,5],[6,4,6,5],[7,4,7,5],[8,4,8,5],[9,4,9,5],[10,4,10,5],[11,4,11,5],[12,4,12,5],[13,4,13,5],[14,4,14,5],[15,4,15,5],[16,4,16,5],[17,4,17,5],[18,4,18,5],[19,4,19,5],[20,4,20,5],[21,4,21,5],[22,4,22,5],[23,4,23,5],[24,4,24,5],[25,4,25,5],[26,4,26,5],[27,4,27,5],[28,4,28,5]],"flags":["formulas_cached_only"]}
[{"$nulls":4},"CDH1 variants identified in DGC cases in the current study."]
["N","Variant’s reference ","Exon / Intron","Frequency Heterozygote (Number)","Genomic position",null,"Sequence variation","Clinvar","Varsome ","Frequency 1000 Genome","Protein Change","Type "]
[1,"rs34033771","5’ UTR ","2,94 (1/34)",68771248,null,"c.-71C>G","B/LB","-","0.006","-"]
[2,"rs1303301430","5’ UTR ","2,94 (1/34)",68771268,null,"c.-51C>T","NI","VUS","8.31767e-06 (gnomeAD)","-"]
[3,"rs1057520826","5’ UTR ","2,94 (1/34)",68771284,null,"c.-36C>A","LB","-","6.97535e-06 (gnomeAD)","-"]
[4,"rs3743674","Intron 1","17,65 (6/34)",68771372,null,"c.48+6 C>T","B","-","0.763","-","SR"]
[5,"rs1801023","Exon 3","5,88 (2/34)",68835754,null,"c.345G>A","B","-","0.003","p.115T=","S"]
[6,"rs751887336","Intron 3","2,94 (1/34)",68835814,null,"c.387+18 T>C","LB","-","2.00652e-05 (gnomeAD)","-","I"]
[7,"rs33932809","Intron 3","2,94 (1/34)",68835823,null,"c.387+27C>T","NI","LB","0.001","-","I"]
[8,"rs33963999","Intron 4","2,94 (1/34)",68835823,null,"c.531+10G>C","B","-","0.018","-","SR"]
[9,"rs200673941","Intron 4","2,94 (1/34)",68842578,null,"c.532-18C>T","B/LB","-","0.00019","-","I"]
[10,"Novel","Exon6","2,94 (1/34)",68844177,null,"c.765G>A","NR","LB","NA","p.255Q=","S"]
[11,"rs142822590","Exon 7","2,94 (1/34)",68845646,null,"c.892G>A","B","-","0.00039","p.A298T","M"]
[12,"rs33950903","Intron 9","23,53 (8/34)",68847443,null,"c.1320+45G>C","NI","B","0.023","-","I"]
[13,"Novel","Intron 10","2,94 (1/34)",68849665,null,"c.1565+3_1565+4delinsGT","NR","VUS","NA","-","In"]
[14,"rs34811340","Intron 10","2,94 (1/34)",68853095,null,"c.1566-88C>T","NI","LB","0.00039","-","I"]
[15,"rs9934882","Intron 10","17,65 (6/34)",68853103,null,"c.1566-80C>G","NI","B","0.040","-","I"]
[16,"rs35741240","Exon 11","2,94 (1/34)",68853297,null,"c.1680 G>C","B/LB","B","0.002","p.560T=","S"]
[17,"rs34582129","Intron 11","5,88 (2/34)",68855852,null,"c.1712-52G>C","NI","LB","0.013","-","I"]
[18,"rs33969373","Exon 12","14,71 (5/34)",68856088,null,"c.1896C>T","B","-","0.023","p.632H=","S"]
[19,"rs35187787","Exon 12","2,94 (1/34)",68855966,null,"c.1774G>A","B","-","0.001","p.A592T","M"]
[20,"rs2276330","Intron 12","14,71 (5/34)",68857289,null,"c.1937-13T>C","B","-","0.058","-","I"]
[21,"rs1801552","Exon 13","32,35 (11/34)",68857441,null,"c.2076T>C","B","-","0.719","p.692A=","S"]
[22,"rs34939176","Intron 13","2,94 (1/34)",68857545,null,"c.2164+17dupA","B",null,"0.04593",null,"I"]
[23,"rs779648243","Exon14","2,94 (1/34)",68862193,null,"c.2281 G>A","VUS","VUS","1.19306e-05 (gnomeAD)","p.G761R","M"]
[24,"rs143044978","Intron 14","2,94 (1/34)",68862373,null,"c.2295+166C>T","LB","-","0.003","-","I"]
[25,"rs33965115","Intron 15","14,71 (5/34)",68863752,null,"c.2439+52 G>A","NI","B","0.019","-","I"]
[26,"rs140328601","Exon 16","2,94 (1/34)",68867273,null,"c.2520C>T","B","-",0.00306,"p.840S=","S"]
[27,"rs2229044","Exon 16","17,65 (6/34)",68867387,null,"c.2634C>T","B","-","0.018","p.878G=","S"]
[]
[]
[]
[]
[{"$nulls":4},"5’UTR: 5’ Untranslated Region ;B : Benign ; LB : Likely Benign ;P : Pathogenic ; VUS : Variant of Uncertain Significance ; NR : Not reported ;NI : Non Indicated;  Hz: Heterozygous status"]
[{"$nulls":4},"S:Synonymous Variant; M:Missense Variant; I: Intronic Variant, SR, Splice Region Variant; In:Indel"]

{"sheet":"Feuil2","index":1,"n_rows":0,"n_cols":0,"rows_kept":0,"flags":["formulas_cached_only"]}

{"sheet":"Feuil3","index":2,"n_rows":0,"n_cols":0,"rows_kept":0,"flags":["formulas_cached_only"]}