{"text_format":"3","workbook":"xlsx","n_sheets":2,"sheets":["Annotation","Enrichment"],"not_rendered":{"comments":2},"read":"whole","date_system":"1900"}

{"sheet":"Annotation","index":0,"n_rows":64,"n_cols":32,"rows_kept":64}
["Symbols","Gene ID","Type","Homologene Gene ID","Gene Symbol","Description","Biological Process (GO)","Protein Function (Protein Atlas)","Subcellular Location (Protein Atlas)","Drug (DrugBank)","Canonical Pathways\r\n","Hallmark Gene Sets\r\n","GO:0043062 extracellular structure organi","GO:0001568 blood vessel development","GO:0045596 negative regulation of cell di","GO:0006882 cellular zinc ion homeostasis","GO:0001503 ossification","R-HSA-211935 Fatty acids","M5885 NABA MATRISOME ASSOCIATED","GO:0030595 leukocyte chemotaxis","GO:0002573 myeloid leukocyte differentiat","GO:0008285 negative regulation of cell pr","M167 PID AP1 PATHWAY","GO:0045992 negative regulation of embryon","GO:0048514 blood vessel morphogenesis","GO:0060291 long-term synaptic potentiatio","GO:0033273 response to vitamin","GO:0060840 artery development","GO:0043112 receptor metabolic process","GO:0043393 regulation of protein binding","GO:0052548 regulation of endopeptidase ac","GO:0071300 cellular response to retinoic "]
["S100A8","6279","symbol","6279","S100A8","S100 calcium binding protein A8","GO:0070488 neutrophil aggregation;GO:0035425 autocrine signaling;GO:0032119 sequestering of zinc ion","Cancer-related genes:Candidate cancer biomarkers; Predicted secreted proteins; Predicted intracellular proteins","Intermediate filaments (reliability']); Additional: Cytosol","Calcium; Zinc; Copper; Zinc acetate; Zinc chloride; Zinc sulfate, unspecified form","(M264)PID TOLL ENDOGENOUS PATHWAY; (M5883)NABA SECRETED FACTORS; (M5885)NABA MATRISOME ASSOCIATED",null,"1.0","1.0","0.0","1.0","0.0","0.0","1.0","1.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","1.0","0.0"]
["CXCL8","3576","symbol","3576","CXCL8","C-X-C motif chemokine ligand 8","GO:2000535 regulation of entry of bacterium into host cell;GO:0060354 negative regulation of cell adhesion molecule production;GO:0050930 induction of positive chemotaxis","Cancer-related genes:Candidate cancer biomarkers; Candidate cardiovascular disease genes; Predicted secreted proteins",null,"ABT-510; MDX-018; Rivanicline; Tapinarof","(M251)PID SYNDECAN 3 PATHWAY; (M252)PID IL8 CXCR1 PATHWAY; (M240)PID SYNDECAN 2 PATHWAY","(M5930)HALLMARK EPITHELIAL MESENCHYMAL TRANSITION; (M5932)HALLMARK INFLAMMATORY RESPONSE","1.0","1.0","0.0","1.0","0.0","0.0","1.0","1.0","0.0","1.0","1.0","0.0","1.0","0.0","1.0","0.0","1.0","0.0","0.0","0.0"]
["MT2A","4502","symbol","4502","MT2A","metallothionein 2A","GO:0036015 response to interleukin-3;GO:0036016 cellular response to interleukin-3;GO:0036018 cellular response to erythropoietin","Predicted intracellular proteins",null,"Zinc; Zinc acetate; Zinc chloride; Zinc sulfate, unspecified form","(M167)PID AP1 PATHWAY","(M5891)HALLMARK HYPOXIA; (M5901)HALLMARK G2M CHECKPOINT; (M5913)HALLMARK INTERFERON GAMMA RESPONSE","0.0","0.0","0.0","1.0","0.0","0.0","0.0","0.0","0.0","0.0","1.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0"]
["CTHRC1","115908","symbol","115908","CTHRC1","collagen triple helix repeat containing 1","GO:0043932 ossification involved in bone remodeling;GO:0033690 positive regulation of osteoblast proliferation;GO:0090177 establishment of planar polarity involved in neural tube closure","Disease related genes; Predicted secreted proteins; Predicted intracellular proteins","Nucleoplasm (reliability'])",null,"(M77)PID WNT SIGNALING PATHWAY; (M23)PID WNT NONCANONICAL PATHWAY; (M3008)NABA ECM GLYCOPROTEINS","(M5930)HALLMARK EPITHELIAL MESENCHYMAL TRANSITION","1.0","0.0","1.0","0.0","1.0","0.0","0.0","0.0","0.0","0.0","0.0","1.0","0.0","0.0","0.0","0.0","0.0","1.0","0.0","0.0"]
["MMP11","4320","symbol","4320","MMP11","matrix metallopeptidase 11","GO:0071711 basement membrane organization;GO:0030574 collagen catabolic process;GO:0045599 negative regulation of fat cell differentiation","FDA approved drug targets:Small molecule drugs; Cancer-related genes:Candidate cancer biomarkers; Predicted secreted proteins; Enzymes; Peptidases:Metallopeptidases",null,"Marimastat; NÎ±-[(2S)-2-{[(S)-[(1S)-1-{[(Benzyloxy)carbonyl]amino}-2-phenylethyl](hydroxy)phosphoryl]methyl}-5-phenylpentanoyl]-L-tryptophanamide","(M3468)NABA ECM REGULATORS; (M5885)NABA MATRISOME ASSOCIATED; (M5889)NABA MATRISOME","(M5946)HALLMARK COAGULATION; (M5953)HALLMARK KRAS SIGNALING UP","1.0","0.0","1.0","0.0","0.0","0.0","1.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0"]
["COL1A1","1277","symbol","1277","COL1A1","collagen type I alpha 1 chain","GO:1902618 cellular response to fluoride;GO:0071306 cellular response to vitamin E;GO:1902617 response to fluoride","Predicted intracellular proteins; Disease related genes; FDA approved drug targets:Biotech drugs; Cancer-related genes:Candidate cancer biomarkers; Predicted secreted proteins","Cytosol (reliability']); Additional: Vesicles","Collagenase clostridium histolyticum; Halofuginone; Clove oil; Vonicog Alfa; Von Willebrand Factor Human","(M274)PID LYMPH ANGIOGENESIS PATHWAY; (M53)PID INTEGRIN3 PATHWAY; (M3005)NABA COLLAGENS","(M5942)HALLMARK UV RESPONSE DN; (M5909)HALLMARK MYOGENESIS; (M5930)HALLMARK EPITHELIAL MESENCHYMAL TRANSITION","1.0","1.0","1.0","1.0","1.0","0.0","0.0","1.0","0.0","0.0","0.0","0.0","1.0","0.0","1.0","0.0","0.0","1.0","0.0","1.0"]
["SULF1","23213","symbol","23213","SULF1","sulfatase 1","GO:0014846 esophagus smooth muscle contraction;GO:0060686 negative regulation of prostatic bud formation;GO:0060685 regulation of prostatic bud formation","Predicted intracellular proteins",null,null,"(M3468)NABA ECM REGULATORS; (M5885)NABA MATRISOME ASSOCIATED; (M5889)NABA MATRISOME",null,"1.0","1.0","1.0","0.0","0.0","0.0","1.0","0.0","0.0","1.0","0.0","1.0","1.0","0.0","1.0","0.0","0.0","0.0","0.0","0.0"]
["SPP1","6696","symbol","6696","SPP1","secreted phosphoprotein 1","GO:0048673 collateral sprouting of intact axon in response to injury;GO:0048683 regulation of collateral sprouting of intact axon in response to injury;GO:0048685 negative regulation of collateral sprouting of intact axon in response to injury","Cancer-related genes:Candidate cancer biomarkers; Predicted secreted proteins","Golgi apparatus (reliability'])",null,"(M118)PID INTEGRIN A9B1 PATHWAY; (M63)PID AVB3 OPN PATHWAY; (M277)PID INTEGRIN A4B1 PATHWAY","(M5944)HALLMARK ANGIOGENESIS; (M5947)HALLMARK IL2 STAT5 SIGNALING; (M5930)HALLMARK EPITHELIAL MESENCHYMAL TRANSITION","1.0","0.0","1.0","1.0","1.0","0.0","0.0","0.0","0.0","0.0","1.0","0.0","1.0","1.0","1.0","1.0","0.0","0.0","0.0","0.0"]
["COL5A2","1290","symbol","1290","COL5A2","collagen type V alpha 2 chain","GO:1903225 negative regulation of endodermal cell differentiation;GO:1903224 regulation of endodermal cell differentiation;GO:2000542 negative regulation of gastrulation","Disease related genes; Predicted secreted proteins; Predicted intracellular proteins",null,null,"(M3005)NABA COLLAGENS; (M198)PID SYNDECAN 1 PATHWAY; (M18)PID INTEGRIN1 PATHWAY","(M5944)HALLMARK ANGIOGENESIS; (M5942)HALLMARK UV RESPONSE DN; (M5930)HALLMARK EPITHELIAL MESENCHYMAL TRANSITION","1.0","0.0","1.0","0.0","1.0","0.0","0.0","0.0","0.0","0.0","0.0","1.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0"]
["CXCL10","3627","symbol","3627","CXCL10","C-X-C motif chemokine ligand 10","GO:1901740 negative regulation of myoblast fusion;GO:0034242 negative regulation of syncytium formation by plasma membrane fusion;GO:1901509 regulation of endothelial tube morphogenesis","Cancer-related genes:Candidate cancer biomarkers; Predicted secreted proteins",null,"N-Methylleucine; Eldelumab; Clove oil","(M222)PID CXCR3 PATHWAY; (M5883)NABA SECRETED FACTORS; (M5885)NABA MATRISOME ASSOCIATED","(M5897)HALLMARK IL6 JAK STAT3 SIGNALING; (M5911)HALLMARK INTERFERON ALPHA RESPONSE; (M5947)HALLMARK IL2 STAT5 SIGNALING","0.0","1.0","1.0","1.0","0.0","0.0","1.0","1.0","0.0","0.0","0.0","0.0","1.0","0.0","1.0","1.0","0.0","0.0","0.0","1.0"]
["S100A9","6280","symbol","6280","S100A9","S100 calcium binding protein A9","GO:0035606 peptidyl-cysteine S-trans-nitrosylation;GO:0070488 neutrophil aggregation;GO:0045113 regulation of integrin biosynthetic process","Cancer-related genes:Candidate cancer biomarkers; Predicted secreted proteins; Predicted intracellular proteins","Cell Junctions;Cytosol;Nucleoplasm (reliability'])","Calcium; Zinc; Zinc acetate; Zinc chloride; Zinc sulfate, unspecified form","(M264)PID TOLL ENDOGENOUS PATHWAY; (M5883)NABA SECRETED FACTORS; (M5885)NABA MATRISOME ASSOCIATED","(M5907)HALLMARK ESTROGEN RESPONSE LATE; (M5921)HALLMARK COMPLEMENT","0.0","0.0","0.0","1.0","0.0","0.0","1.0","1.0","0.0","0.0","0.0","0.0","0.0","1.0","0.0","0.0","0.0","0.0","1.0","0.0"]
["VCAN","1462","symbol","1462","VCAN","versican","GO:0030208 dermatan sulfate biosynthetic process;GO:0030205 dermatan sulfate metabolic process;GO:0030207 chondroitin sulfate catabolic process","Disease related genes; Predicted secreted proteins; Predicted intracellular proteins","Vesicles (reliability'])","Hyaluronic acid","(M264)PID TOLL ENDOGENOUS PATHWAY; (M5882)NABA PROTEOGLYCANS; (M223)PID BETA CATENIN NUC PATHWAY","(M5944)HALLMARK ANGIOGENESIS; (M5915)HALLMARK APICAL JUNCTION; (M5930)HALLMARK EPITHELIAL MESENCHYMAL TRANSITION","1.0","0.0","0.0","0.0","1.0","0.0","0.0","1.0","0.0","0.0","1.0","0.0","0.0","0.0","0.0","1.0","0.0","0.0","0.0","0.0"]
["COL6A3","1293","symbol","1293","COL6A3","collagen type VI alpha 3 chain","GO:0010951 negative regulation of endopeptidase activity;GO:0010466 negative regulation of peptidase activity;GO:0045861 negative regulation of proteolysis","Disease related genes; Predicted secreted proteins; Predicted intracellular proteins",null,null,"(M5887)NABA BASEMENT MEMBRANES; (M3005)NABA COLLAGENS; (M198)PID SYNDECAN 1 PATHWAY","(M5909)HALLMARK MYOGENESIS; (M5930)HALLMARK EPITHELIAL MESENCHYMAL TRANSITION","1.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","1.0","0.0"]
["MMP9","4318","symbol","4318","MMP9","matrix metallopeptidase 9","GO:2000697 negative regulation of epithelial cell differentiation involved in kidney development;GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway;GO:1900122 positive regulation of receptor binding","FDA approved drug targets:Small molecule drugs; Disease related genes; ENZYME proteins:Hydrolases; Cancer-related genes:Candidate cancer biomarkers; Predicted secreted proteins; Enzymes; Candidate cardiovascular disease genes; Peptidases:Metallopeptidases","Cytosol (reliability'])","Glutathione; Marimastat; Minocycline; Captopril; Glucosamine; Zinc; 2-Amino-N,3,3-Trimethylbutanamide; 2-{[Formyl(Hydroxy)Amino]Methyl}-4-Methylpentanoic Acid; AE-941; PG-530742; Endostatin; 5-(4-PHENOXYPHENYL)-5-(4-PYRIMIDIN-2-YLPIPERAZIN-1-YL)PYRIMIDINE-2,4,6(2H,3H)-TRIONE; (2R)-2-AMINO-3,3,3-TRIFLUORO-N-HYDROXY-2-{[(4-PHENOXYPHENYL)SULFONYL]METHYL}PROPANAMIDE; (3R)-4,4-DIFLUORO-3-[(4-METHOXYPHENYL)SULFONYL]BUTANOIC ACID; Zinc acetate; Zinc chloride; Zinc sulfate, unspecified form","(M63)PID AVB3 OPN PATHWAY; (M165)PID SYNDECAN 4 PATHWAY; (M65)PID FRA PATHWAY","(M5946)HALLMARK COAGULATION; (M5915)HALLMARK APICAL JUNCTION; (M5950)HALLMARK ALLOGRAFT REJECTION","1.0","0.0","1.0","1.0","0.0","0.0","1.0","1.0","1.0","0.0","1.0","1.0","0.0","0.0","1.0","0.0","0.0","1.0","1.0","1.0"]
["COL1A2","1278","symbol","1278","COL1A2","collagen type I alpha 2 chain","GO:0070208 protein heterotrimerization;GO:0043589 skin morphogenesis;GO:0070206 protein trimerization","Cancer-related genes:Candidate cancer biomarkers; Disease related genes; Predicted secreted proteins","Endoplasmic reticulum (reliability'])","Collagenase clostridium histolyticum","(M274)PID LYMPH ANGIOGENESIS PATHWAY; (M65)PID FRA PATHWAY; (M53)PID INTEGRIN3 PATHWAY","(M5942)HALLMARK UV RESPONSE DN; (M5930)HALLMARK EPITHELIAL MESENCHYMAL TRANSITION","1.0","1.0","0.0","0.0","1.0","0.0","0.0","1.0","0.0","0.0","1.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0"]
["TMEM158","25907","symbol","25907","TMEM158","transmembrane protein 158",{"$nulls":5},"(M5953)HALLMARK KRAS SIGNALING UP","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0"]
["COL5A1","1289","symbol","1289","COL5A1","collagen type V alpha 1 chain","GO:1903225 negative regulation of endodermal cell differentiation;GO:1903224 regulation of endodermal cell differentiation;GO:0045112 integrin biosynthetic process","Disease related genes; Predicted secreted proteins; Predicted intracellular proteins; Cancer-related genes:Mutated cancer genes","Vesicles (reliability'])",null,"(M3005)NABA COLLAGENS; (M198)PID SYNDECAN 1 PATHWAY; (M236)PID DELTA NP63 PATHWAY","(M5891)HALLMARK HYPOXIA; (M5930)HALLMARK EPITHELIAL MESENCHYMAL TRANSITION; (M5937)HALLMARK GLYCOLYSIS","1.0","1.0","1.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","1.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0"]
["MT1G","4495","symbol","4495","MT1G","metallothionein 1G","GO:0042117 monocyte activation;GO:0010273 detoxification of copper ion;GO:1990169 stress response to copper ion","Cancer-related genes:Candidate cancer biomarkers; Predicted intracellular proteins",{"$nulls":4},"0.0","1.0","0.0","1.0","0.0","0.0","0.0","1.0","1.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0"]
["POSTN","10631","symbol","10631","POSTN","periostin","GO:0071307 cellular response to vitamin K;GO:0032571 response to vitamin K;GO:1990523 bone regeneration","Cancer-related genes:Candidate cancer biomarkers; Predicted secreted proteins","Golgi apparatus (reliability']); Additional: Nucleoplasm",null,"(M3008)NABA ECM GLYCOPROTEINS; (M5884)NABA CORE MATRISOME; (M5889)NABA MATRISOME","(M5944)HALLMARK ANGIOGENESIS; (M5930)HALLMARK EPITHELIAL MESENCHYMAL TRANSITION","1.0","1.0","1.0","1.0","1.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","1.0","1.0","0.0","0.0","0.0","0.0"]
["COL3A1","1281","symbol","1281","COL3A1","collagen type III alpha 1 chain","GO:0060414 aorta smooth muscle tissue morphogenesis;GO:2001223 negative regulation of neuron migration;GO:0048745 smooth muscle tissue development","Disease related genes; Predicted secreted proteins; Predicted intracellular proteins","Endoplasmic reticulum (reliability'])","Collagenase clostridium histolyticum","(M3005)NABA COLLAGENS; (M198)PID SYNDECAN 1 PATHWAY; (M8)PID ENDOTHELIN PATHWAY","(M5944)HALLMARK ANGIOGENESIS; (M5942)HALLMARK UV RESPONSE DN; (M5909)HALLMARK MYOGENESIS","1.0","1.0","1.0","0.0","0.0","0.0","0.0","0.0","1.0","0.0","0.0","0.0","1.0","0.0","1.0","1.0","0.0","0.0","0.0","0.0"]
["APOE","348","symbol","348","APOE","apolipoprotein E","GO:0071831 intermediate-density lipoprotein particle clearance;GO:1903000 regulation of lipid transport across blood brain barrier;GO:1903002 positive regulation of lipid transport across blood brain barrier","Disease related genes; Cancer-related genes:Candidate cancer biomarkers; Candidate cardiovascular disease genes; Predicted secreted proteins","Vesicles (reliability'])","Zinc; Copper; Zinc acetate; Zinc chloride; Zinc sulfate, unspecified form",null,"(M5905)HALLMARK ADIPOGENESIS; (M5934)HALLMARK XENOBIOTIC METABOLISM","1.0","1.0","1.0","1.0","0.0","0.0","0.0","1.0","0.0","1.0","0.0","0.0","1.0","1.0","1.0","1.0","1.0","1.0","1.0","1.0"]
["MMD","23531","symbol","23531","MMD","monocyte to macrophage differentiation associated","GO:0019835 cytolysis;GO:0045666 positive regulation of neuron differentiation;GO:0050769 positive regulation of neurogenesis","Transporters:Transporter channels and pores","Vesicles (reliability'])",null,null,"(M5953)HALLMARK KRAS SIGNALING UP","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","1.0","0.0","0.0","0.0","0.0","0.0","0.0"]
["MT1X","4501","symbol","4501","MT1X","metallothionein 1X","GO:0036018 cellular response to erythropoietin;GO:0036017 response to erythropoietin;GO:0010273 detoxification of copper ion","Predicted intracellular proteins",{"$nulls":4},"0.0","0.0","0.0","1.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0"]
["CHST15","51363","symbol","51363","CHST15","carbohydrate sulfotransferase 15","GO:0030206 chondroitin sulfate biosynthetic process;GO:0050650 chondroitin sulfate proteoglycan biosynthetic process;GO:0030204 chondroitin sulfate metabolic process","ENZYME proteins:Transferases; Predicted intracellular proteins; Enzymes","Cytosol (reliability']); Additional: Centrosome",{"$nulls":3},"0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0"]
["649923",{"$nulls":3},"None","None","None","None","None","None","None","None","nan","nan","nan","nan","nan","nan","nan","nan","nan","nan","nan","nan","nan","nan","nan","nan","nan","nan","nan","nan"]
["FCER1G","2207","symbol","2207","FCER1G","Fc fragment of IgE receptor Ig","GO:0001802 type III hypersensitivity;GO:0001803 regulation of type III hypersensitivity;GO:0001805 positive regulation of type III hypersensitivity","FDA approved drug targets:Small molecule drugs",null,"Benzylpenicilloyl polylysine","(M7)PID FCER1 PATHWAY","(M5921)HALLMARK COMPLEMENT; (M5953)HALLMARK KRAS SIGNALING UP","1.0","0.0","0.0","0.0","0.0","0.0","0.0","1.0","1.0","0.0","0.0","0.0","0.0","1.0","0.0","0.0","1.0","0.0","0.0","0.0"]
["GREM1","26585","symbol","26585","GREM1","gremlin 1, DAN family BMP antagonist","GO:1900154 regulation of bone trabecula formation;GO:1900155 negative regulation of bone trabecula formation;GO:0090291 negative regulation of osteoclast proliferation","Disease related genes; Predicted secreted proteins",null,null,"(M181)PID BMP PATHWAY; (M5880)NABA ECM AFFILIATED; (M5885)NABA MATRISOME ASSOCIATED","(M5930)HALLMARK EPITHELIAL MESENCHYMAL TRANSITION","1.0","1.0","1.0","1.0","1.0","0.0","1.0","1.0","0.0","1.0","0.0","1.0","1.0","0.0","1.0","0.0","1.0","1.0","0.0","0.0"]
["THBS2","7058","symbol","7058","THBS2","thrombospondin 2","GO:0051965 positive regulation of synapse assembly;GO:0051963 regulation of synapse assembly;GO:0007416 synapse assembly","Cancer-related genes:Candidate cancer biomarkers; Disease related genes; Predicted secreted proteins","Plasma membrane (reliability']); Additional: Cytosol;Nuclear speckles",null,"(M277)PID INTEGRIN A4B1 PATHWAY; (M18)PID INTEGRIN1 PATHWAY; (M3008)NABA ECM GLYCOPROTEINS","(M5930)HALLMARK EPITHELIAL MESENCHYMAL TRANSITION","1.0","1.0","0.0","0.0","1.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","1.0","1.0","0.0","0.0","0.0","0.0","0.0","0.0"]
["C1QB","713","symbol","713","C1QB","complement C1q B chain","GO:0098883 synapse pruning;GO:0030449 regulation of complement activation;GO:2000257 regulation of protein activation cascade","Disease related genes; Predicted secreted proteins",null,"Cetuximab; Palivizumab; Daclizumab; Bevacizumab; Zinc; Zinc acetate; Zinc chloride; Zinc sulfate, unspecified form","(M5880)NABA ECM AFFILIATED; (M5885)NABA MATRISOME ASSOCIATED; (M5889)NABA MATRISOME",null,"0.0","0.0","0.0","0.0","0.0","0.0","1.0","1.0","0.0","0.0","0.0","1.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0"]
["TYROBP","7305","symbol","7305","TYROBP","transmembrane immune signaling adaptor TYROBP","GO:0110090 positive regulation of hippocampal neuron apoptotic process;GO:0090634 microglial cell mediated cytotoxicity;GO:1904149 regulation of microglial cell mediated cytotoxicity","Disease related genes",{"$nulls":4},"1.0","0.0","1.0","0.0","0.0","0.0","0.0","1.0","1.0","1.0","0.0","0.0","0.0","1.0","0.0","0.0","0.0","0.0","0.0","0.0"]
["SERPINE2","5270","symbol","5270","SERPINE2","serpin family E member 2","GO:0042628 mating plug formation;GO:0045297 post-mating behavior;GO:0061108 seminal vesicle epithelium development","Predicted secreted proteins",null,null,"(M3468)NABA ECM REGULATORS; (M5885)NABA MATRISOME ASSOCIATED; (M5889)NABA MATRISOME","(M5930)HALLMARK EPITHELIAL MESENCHYMAL TRANSITION","1.0","0.0","0.0","1.0","1.0","0.0","1.0","1.0","0.0","1.0","1.0","0.0","0.0","1.0","1.0","0.0","0.0","0.0","1.0","1.0"]
["ST3GAL5","8869","symbol","8869","ST3GAL5","ST3 beta-galactoside alpha-2,3-sialyltransferase 5","GO:0001574 ganglioside biosynthetic process;GO:0097503 sialylation;GO:0001573 ganglioside metabolic process","Predicted intracellular proteins; Disease related genes; Enzymes; Potential drug targets; ENZYME proteins:Transferases","Vesicles (reliability'])","99mTc-14 F7 Mab",null,"(M5913)HALLMARK INTERFERON GAMMA RESPONSE","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0"]
["ID1","3397","symbol","3397","ID1","inhibitor of DNA binding 1, HLH protein","GO:0036164 cell-abiotic substrate adhesion;GO:0010621 negative regulation of transcription by transcription factor localization;GO:0060426 lung vasculature development","Transcription factors:Basic domains; Cancer-related genes:Candidate cancer biomarkers; Predicted intracellular proteins","Nucleoplasm (reliability'])",null,"(M182)PID IL3 PATHWAY; (M185)PID ALK1 PATHWAY; (M288)PID HES HEY PATHWAY","(M5896)HALLMARK TGF BETA SIGNALING; (M5942)HALLMARK UV RESPONSE DN","1.0","1.0","1.0","1.0","1.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","1.0","0.0","0.0","1.0","0.0","1.0","0.0","0.0"]
["ALDH1L1","10840","symbol","10840","ALDH1L1","aldehyde dehydrogenase 1 family member L1","GO:0009258 10-formyltetrahydrofolate catabolic process;GO:0009397 folic acid-containing compound catabolic process;GO:0042560 pteridine-containing compound catabolic process","ENZYME proteins:Oxidoreductases; Predicted intracellular proteins; Enzymes","Cytosol (reliability'])","Tetrahydrofolic acid",null,"(M5945)HALLMARK HEME METABOLISM","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0"]
["TMC4","147798","symbol","147798","TMC4","transmembrane channel like 4","GO:0034220 ion transmembrane transport;GO:0055085 transmembrane transport;GO:0006811 ion transport",{"$nulls":5},"0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0"]
["FAM3B","54097","symbol","54097","FAM3B","FAM3 metabolism regulating signaling molecule B","GO:0030073 insulin secretion;GO:0042593 glucose homeostasis;GO:0033500 carbohydrate homeostasis","Predicted secreted proteins; Predicted intracellular proteins","Vesicles (reliability'])",{"$nulls":3},"0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0"]
["NSG1","27065","symbol","27065","NSG1","neuronal vesicle trafficking associated 1","GO:0099627 neurotransmitter receptor cycle;GO:0099630 postsynaptic neurotransmitter receptor cycle;GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane",{"$nulls":3},"(M19)PID P73PATHWAY",null,"0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","1.0","0.0","0.0","1.0","0.0","0.0","0.0"]
["FABP6","2172","symbol","2172","FABP6","fatty acid binding protein 6","GO:0019433 triglyceride catabolic process;GO:0046461 neutral lipid catabolic process;GO:0046464 acylglycerol catabolic process","Predicted intracellular proteins",null,"Cholic Acid; Glycocholic acid; Taurocholic acid",null,"(M5949)HALLMARK PEROXISOME","0.0","0.0","0.0","0.0","0.0","1.0","0.0","0.0","0.0","1.0","0.0","0.0","0.0","0.0","0.0","1.0","0.0","0.0","0.0","0.0"]
["OSR1","130497","symbol","130497","OSR1","odd-skipped related transcription factor 1","GO:0072165 anterior mesonephric tubule development;GO:0072167 specification of mesonephric tubule identity;GO:0072168 specification of anterior mesonephric tubule identity","Transcription factors:Zinc-coordinating DNA-binding domains; Predicted intracellular proteins",{"$nulls":4},"1.0","1.0","1.0","0.0","1.0","0.0","0.0","0.0","0.0","0.0","0.0","1.0","1.0","0.0","0.0","0.0","0.0","1.0","1.0","1.0"]
["CYP2J2","1573","symbol","1573","CYP2J2","cytochrome P450 family 2 subfamily J member 2","GO:0019373 epoxygenase P450 pathway;GO:0043651 linoleic acid metabolic process;GO:0042738 exogenous drug catabolic process","ENZYME proteins:Oxidoreductases; Predicted intracellular proteins; Enzymes",{"$nulls":3},"(M5934)HALLMARK XENOBIOTIC METABOLISM","0.0","0.0","0.0","0.0","0.0","1.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0"]
["CYP4F22","126410","symbol","126410","CYP4F22","cytochrome P450 family 4 subfamily F member 22","GO:0046513 ceramide biosynthetic process;GO:0006672 ceramide metabolic process;GO:0030148 sphingolipid biosynthetic process","Disease related genes",{"$nulls":4},"0.0","0.0","0.0","0.0","0.0","1.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0"]
["SMAD6","4091","symbol","4091","SMAD6","SMAD family member 6","GO:0007352 zygotic specification of dorsal/ventral axis;GO:0010991 negative regulation of SMAD protein complex assembly;GO:0010990 regulation of SMAD protein complex assembly","Transcription factors:beta-Hairpin exposed by an alpha/beta-scaffold; Disease related genes; Predicted intracellular proteins","Nucleoplasm (reliability']); Additional: Golgi apparatus;Nuclear bodies",null,"(M181)PID BMP PATHWAY","(M5896)HALLMARK TGF BETA SIGNALING","0.0","1.0","1.0","0.0","1.0","0.0","0.0","1.0","0.0","1.0","0.0","0.0","0.0","0.0","0.0","1.0","0.0","0.0","0.0","0.0"]
["CYP4F12","66002","symbol","66002","CYP4F12","cytochrome P450 family 4 subfamily F member 12","GO:0003095 pressure natriuresis;GO:0042361 menaquinone catabolic process;GO:0042377 vitamin K catabolic process","Predicted intracellular proteins",{"$nulls":4},"1.0","0.0","0.0","1.0","0.0","1.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","1.0","0.0","0.0","0.0","0.0"]
["GPX2","2877","symbol","2877","GPX2","glutathione peroxidase 2","GO:0098869 cellular oxidant detoxification;GO:1990748 cellular detoxification;GO:0098754 detoxification","ENZYME proteins:Oxidoreductases; Cancer-related genes:Candidate cancer biomarkers; Predicted intracellular proteins; Enzymes","Nucleoplasm (reliability']); Additional: Cytosol","Glutathione","(M236)PID DELTA NP63 PATHWAY; (M256)PID TAP63 PATHWAY","(M5939)HALLMARK P53 PATHWAY","0.0","0.0","0.0","1.0","0.0","1.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","1.0","0.0","0.0","0.0","1.0","0.0","0.0"]
["CYP4B1","1580","symbol","1580","CYP4B1","cytochrome P450 family 4 subfamily B member 1","GO:0018917 fluorene metabolic process;GO:0018879 biphenyl metabolic process;GO:0042537 benzene-containing compound metabolic process","ENZYME proteins:Oxidoreductases; Predicted intracellular proteins; Enzymes","Vesicles (reliability'])",null,null,"(M5905)HALLMARK ADIPOGENESIS","0.0","0.0","0.0","0.0","0.0","1.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0"]
["FAM174B","400451","symbol","400451","FAM174B","family with sequence similarity 174 member B","GO:0007030 Golgi organization;GO:0010256 endomembrane system organization;GO:0006996 organelle organization","Predicted intracellular proteins","Intermediate filaments (reliability'])",{"$nulls":3},"0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0"]
["PHGR1","644844","symbol","644844","PHGR1","proline, histidine and glycine rich 1",null,"Predicted intracellular proteins","Vesicles (reliability'])",{"$nulls":3},"0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0"]
["SNX31","169166","symbol","169166","SNX31","sorting nexin 31","GO:1990126 retrograde transport, endosome to plasma membrane;GO:0098876 vesicle-mediated transport to the plasma membrane;GO:0016197 endosomal transport","Transporters; Predicted intracellular proteins","Golgi apparatus;Nucleoplasm (reliability']); Additional: Cytosol",{"$nulls":3},"0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0"]
["CTSE","1510","symbol","1510","CTSE","cathepsin E","GO:0016540 protein autoprocessing;GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0002495 antigen processing and presentation of peptide antigen via MHC class II","ENZYME proteins:Hydrolases; Peptidases:Aspartic-type peptidases; Predicted intracellular proteins; Enzymes",null,null,"(M3468)NABA ECM REGULATORS; (M5885)NABA MATRISOME ASSOCIATED; (M5889)NABA MATRISOME","(M5946)HALLMARK COAGULATION; (M5945)HALLMARK HEME METABOLISM","0.0","0.0","0.0","0.0","0.0","0.0","1.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0"]
["BCAS1","8537","symbol","8537","BCAS1","brain enriched myelin associated protein 1","GO:0042552 myelination;GO:0007272 ensheathment of neurons;GO:0008366 axon ensheathment","Predicted intracellular proteins","Vesicles (reliability'])",{"$nulls":3},"0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0"]
["UPK2","7379","symbol","7379","UPK2","uroplakin 2","GO:0030855 epithelial cell differentiation;GO:0060429 epithelium development;GO:0009888 tissue development","Transporters:Accessory Factors Involved in Transport",{"$nulls":4},"0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0"]
["TESC","54997","symbol","54997","TESC","tescalcin","GO:0032417 positive regulation of sodium:proton antiporter activity;GO:0032415 regulation of sodium:proton antiporter activity;GO:0030854 positive regulation of granulocyte differentiation","Predicted intracellular proteins","Nucleoplasm (reliability']); Additional: Cytosol",{"$nulls":3},"1.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","1.0","1.0","0.0","0.0","1.0","0.0","1.0","0.0","0.0","0.0","0.0","1.0"]
["HPGD","3248","symbol","3248","HPGD","15-hydroxyprostaglandin dehydrogenase","GO:1905828 regulation of prostaglandin catabolic process;GO:1905344 prostaglandin catabolic process;GO:0097070 ductus arteriosus closure","ENZYME proteins:Oxidoreductases; Predicted intracellular proteins; Disease related genes; Cancer-related genes:Candidate cancer biomarkers; Enzymes; Potential drug targets","Cytosol (reliability']); Additional: Nucleoplasm","NADH",null,"(M5908)HALLMARK ANDROGEN RESPONSE; (M5935)HALLMARK FATTY ACID METABOLISM","0.0","1.0","1.0","1.0","0.0","1.0","0.0","1.0","0.0","0.0","1.0","0.0","1.0","0.0","0.0","1.0","0.0","0.0","0.0","0.0"]
["PSCA","8000","symbol","8000","PSCA","prostate stem cell antigen","GO:0070373 negative regulation of ERK1 and ERK2 cascade;GO:0099601 regulation of neurotransmitter receptor activity;GO:0010469 regulation of signaling receptor activity","Cancer-related genes:Candidate cancer biomarkers; Predicted intracellular proteins","Plasma membrane (reliability'])",{"$nulls":3},"0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","1.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","1.0","0.0"]
["C10orf99","387695","symbol","387695","C10orf99","chromosome 10 open reading frame 99","GO:0051782 negative regulation of cell division;GO:0050832 defense response to fungus;GO:2000404 regulation of T cell migration","Predicted secreted proteins",{"$nulls":4},"0.0","0.0","0.0","0.0","0.0","0.0","0.0","1.0","0.0","0.0","0.0","0.0","1.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0"]
["ANXA10","11199","symbol","11199","ANXA10","annexin A10",null,"Predicted intracellular proteins","Nucleoli;Nucleoplasm (reliability']); Additional: Vesicles",null,"(M5880)NABA ECM AFFILIATED; (M5885)NABA MATRISOME ASSOCIATED; (M5889)NABA MATRISOME","(M5953)HALLMARK KRAS SIGNALING UP","0.0","0.0","0.0","0.0","0.0","0.0","1.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0"]
["DHRS2","10202","symbol","10202","DHRS2","dehydrogenase/reductase 2","GO:0043011 myeloid dendritic cell differentiation;GO:0001773 myeloid dendritic cell activation;GO:0008207 C21-steroid hormone metabolic process","Predicted intracellular proteins","Mitochondria (reliability']); Additional: Nucleoplasm",null,null,"(M5906)HALLMARK ESTROGEN RESPONSE EARLY; (M5907)HALLMARK ESTROGEN RESPONSE LATE","0.0","0.0","0.0","1.0","0.0","0.0","0.0","1.0","1.0","1.0","0.0","0.0","0.0","0.0","0.0","1.0","0.0","1.0","0.0","0.0"]
["CLCA4","22802","symbol","22802","CLCA4","chloride channel accessory 4","GO:1902476 chloride transmembrane transport;GO:0006821 chloride transport;GO:0098661 inorganic anion transmembrane transport",null,"Plasma membrane (reliability']); Additional: Aggresome;Nucleoplasm",{"$nulls":3},"0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0"]
["VSIG2","23584","symbol","23584","VSIG2","V-set and immunoglobulin domain containing 2",null,null,"Nucleoplasm (reliability'])",{"$nulls":3},"0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0"]
["SPINK1","6690","symbol","6690","SPINK1","serine peptidase inhibitor Kazal type 1","GO:0010751 negative regulation of nitric oxide mediated signal transduction;GO:1900004 negative regulation of serine-type endopeptidase activity;GO:1902572 negative regulation of serine-type peptidase activity","Cancer-related genes:Candidate cancer biomarkers; Disease related genes; Predicted secreted proteins",{"$nulls":4},"0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","1.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","1.0","1.0"]
["BTBD16","118663","symbol","118663","BTBD16","BTB domain containing 16",null,"Predicted intracellular proteins","Nucleoli (reliability']); Additional: Cytosol",{"$nulls":3},"0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0"]
["HMGCS2","3158","symbol","3158","HMGCS2","3-hydroxy-3-methylglutaryl-CoA synthase 2","GO:0010142 farnesyl diphosphate biosynthetic process, mevalonate pathway;GO:1902767 isoprenoid biosynthetic process via mevalonate;GO:0045337 farnesyl diphosphate biosynthetic process","Predicted intracellular proteins; Disease related genes; Enzymes; Potential drug targets; ENZYME proteins:Transferases","Mitochondria (reliability'])",null,"(M254)PID MYC REPRESS PATHWAY","(M5946)HALLMARK COAGULATION; (M5935)HALLMARK FATTY ACID METABOLISM; (M5907)HALLMARK ESTROGEN RESPONSE LATE","0.0","0.0","0.0","0.0","0.0","1.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","1.0","0.0","0.0","0.0","0.0"]
["CRTAC1","55118","symbol","55118","CRTAC1","cartilage acidic protein 1","GO:1900121 negative regulation of receptor binding;GO:0007413 axonal fasciculation;GO:0106030 neuron projection fasciculation","Predicted secreted proteins; Predicted intracellular proteins",{"$nulls":4},"0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","0.0","1.0","0.0","0.0"]

{"sheet":"Enrichment","index":1,"n_rows":349,"n_cols":11,"rows_kept":349}
["GroupID","Category","Term","Description","LogP","P value","Log(q-value)","InTerm_InList",null,"enrichment","Symbols"]
["1_Summary","GO Biological Processes","GO:0043062","extracellular structure organization",-11.9397427456,{"$f":"10^(E2)","v":{"v":1.14883393193394e-12,"d":"1.15E-12"}},{"v":-7.8564438813,"d":"-7.856"},14,458,{"$f":"H2/I2","v":0.0305676855895196},"APOE,COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A3,VCAN,MMP9,MMP11,SPP1,POSTN,SULF1,GREM1,THBS2,CTHRC1,ID1,TYROBP,OSR1,FCER1G,SERPINE2,S100A8,TESC,CXCL8,CYP4F12"]
["1_Member","GO Biological Processes","GO:0043062","extracellular structure organization",-11.9397427456,{"$f":"10^(E3)","v":{"v":1.14883393193394e-12,"d":"1.15E-12"}},{"v":-7.8564438813,"d":"-7.856"},14,458,{"$f":"H3/I3","v":0.0305676855895196},"APOE,COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A3,VCAN,MMP9,MMP11,SPP1,POSTN,SULF1,GREM1"]
["1_Member","Reactome Gene Sets","R-HSA-1442490","Collagen degradation",-11.837240303,{"v":1.45465397148198e-12,"d":"1.45E-12"},{"v":-7.8564438813,"d":"-7.856"},8,64,0.125,"COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A3,MMP9,MMP11"]
["1_Member","Canonical Pathways","M18","PID INTEGRIN1 PATHWAY",-11.725577776,{"v":1.88114478962173e-12,"d":"1.88E-12"},{"v":-7.8564438813,"d":"-7.856"},8,66,0.121212121212121,"COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A3,SPP1,THBS2"]
["1_Member","GO Biological Processes","GO:0030198","extracellular matrix organization",-11.4657819839,{"v":3.42151159503937e-12,"d":"3.42E-12"},{"v":-7.7215868258,"d":"-7.722"},13,397,0.0327455919395466,"COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A3,VCAN,MMP9,MMP11,SPP1,POSTN,SULF1,GREM1"]
["1_Member","Canonical Pathways","M198","PID SYNDECAN 1 PATHWAY",-11.0355114158,{"v":9.21485666381769e-12,"d":"9.21E-12"},{"v":-7.3882262708,"d":"-7.388"},7,46,0.152173913043478,"COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A3,MMP9"]
["1_Member","Canonical Pathways","M5884","NABA CORE MATRISOME",-10.6583302875,{"v":2.19618900266274e-11,"d":"2.20E-11"},{"v":-7.1106643138,"d":"-7.111"},11,275,0.04,"COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A3,VCAN,SPP1,THBS2,POSTN,CTHRC1"]
["1_Member","Reactome Gene Sets","R-HSA-1474228","Degradation of the extracellular matrix",-10.6118214231,{"v":2.44443546984811e-11,"d":"2.44E-11"},{"v":-7.1106643138,"d":"-7.111"},9,140,0.0642857142857143,"COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A3,MMP9,MMP11,SPP1"]
["1_Member","GO Biological Processes","GO:0030199","collagen fibril organization",-10.4634522189,{"v":3.43991555266432e-11,"d":"3.44E-11"},{"v":-7.0202870565,"d":"-7.020"},7,55,0.127272727272727,"COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,MMP11,GREM1"]
["1_Member","Reactome Gene Sets","R-HSA-2022090","Assembly of collagen fibrils and other multimeric structures",-10.1355230176,{"v":7.31942529230436e-11,"d":"7.32E-11"},{"v":-6.7435103777,"d":"-6.744"},7,61,0.114754098360656,"COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A3,MMP9"]
["1_Member","Canonical Pathways","M160","PID AVB3 INTEGRIN PATHWAY",-9.5298272307,{"v":2.95238349851609e-10,"d":"2.95E-10"},{"v":-6.1835720814,"d":"-6.184"},7,74,0.0945945945945946,"COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A3,SPP1"]
["1_Member","Reactome Gene Sets","R-HSA-3000178","ECM proteoglycans",-9.4468056541,{"v":3.57432752800604e-10,"d":"3.57E-10"},{"v":-6.1419431899,"d":"-6.142"},7,76,0.0921052631578947,"COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A3,VCAN"]
["1_Member","Canonical Pathways","M3005","NABA COLLAGENS",-9.2157081453,{"v":6.08543817684563e-10,"d":"6.09E-10"},{"v":-5.9833963483,"d":"-5.983"},6,44,0.136363636363636,"COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A3"]
["1_Member","Reactome Gene Sets","R-HSA-8948216","Collagen chain trimerization",-9.2157081453,{"v":6.08543817684563e-10,"d":"6.09E-10"},{"v":-5.9833963483,"d":"-5.983"},6,44,0.136363636363636,"COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A3"]
["1_Member","Reactome Gene Sets","R-HSA-216083","Integrin cell surface interactions",-9.099860596,{"v":7.94583246730524e-10,"d":"7.95E-10"},{"v":-5.8997334823,"d":"-5.900"},7,85,0.0823529411764706,"COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A3,SPP1"]
["1_Member","Reactome Gene Sets","R-HSA-1474244","Extracellular matrix organization",-8.9326608646,{"v":1.16772112067005e-9,"d":"1.17E-09"},{"v":-5.7814249369,"d":"-5.781"},10,301,0.0332225913621262,"COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A3,VCAN,MMP9,MMP11,SPP1"]
["1_Member","Reactome Gene Sets","R-HSA-1474290","Collagen formation",-8.9235601036,{"v":1.19244922703091e-9,"d":"1.19E-09"},{"v":-5.7814249369,"d":"-5.781"},7,90,0.0777777777777778,"COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A3,MMP9"]
["1_Member","Reactome Gene Sets","R-HSA-186797","Signaling by PDGF",-8.4676980502,{"v":3.40644945932521e-9,"d":"3.41E-09"},{"v":-5.386705911,"d":"-5.387"},6,58,0.103448275862069,"COL3A1,COL5A1,COL5A2,COL6A3,SPP1,THBS2"]
["1_Member","Reactome Gene Sets","R-HSA-3000170","Syndecan interactions",-8.4542074594,{"v":3.51392542699254e-9,"d":"3.51E-09"},{"v":-5.386705911,"d":"-5.387"},5,27,0.185185185185185,"COL1A1,COL1A2,COL3A1,COL5A1,COL5A2"]
["1_Member","Reactome Gene Sets","R-HSA-8874081","MET activates PTK2 signaling",-8.2096213303,{"v":6.17132857335353e-9,"d":"6.17E-09"},{"v":-5.1643961766,"d":"-5.164"},5,30,0.166666666666667,"COL1A1,COL1A2,COL3A1,COL5A1,COL5A2"]
["1_Member","Reactome Gene Sets","R-HSA-1650814","Collagen biosynthesis and modifying enzymes",-8.0824842424,{"v":8.27019514950321e-9,"d":"8.27E-09"},{"v":-5.0584483878,"d":"-5.058"},6,67,0.0895522388059701,"COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A3"]
["1_Member","Reactome Gene Sets","R-HSA-9006934","Signaling by Receptor Tyrosine Kinases",-7.8739480202,{"v":1.33675550044771e-8,"d":"1.34E-08"},{"v":-4.8894207068,"d":"-4.889"},11,506,0.0217391304347826,"APOE,COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A3,ID1,MMP9,SPP1,THBS2"]
["1_Member","Reactome Gene Sets","R-HSA-8875878","MET promotes cell motility",-7.4968518131,{"v":3.18528419652929e-8,"d":"3.19E-08"},{"v":-4.5977546951,"d":"-4.598"},5,41,0.121951219512195,"COL1A1,COL1A2,COL3A1,COL5A1,COL5A2"]
["1_Member","KEGG Pathway","ko04974","Protein digestion and absorption",-7.3045161001,{"v":4.96002539323273e-8,"d":"4.96E-08"},{"v":-4.4206589487,"d":"-4.421"},6,90,0.0666666666666667,"COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A3"]
["1_Member","KEGG Pathway","hsa04974","Protein digestion and absorption",-7.1909759085,{"v":6.44205000333269e-8,"d":"6.44E-08"},{"v":-4.3218420139,"d":"-4.322"},6,94,0.0638297872340425,"COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL6A3"]
["1_Member","Reactome Gene Sets","R-HSA-3000480","Scavenging by Class A Receptors",-7.0838633328,{"v":8.24397502081475e-8,"d":"8.24E-08"},{"v":-4.2427581617,"d":"-4.243"},4,19,0.210526315789474,"APOE,COL1A1,COL1A2,COL3A1"]
["1_Member","GO Biological Processes","GO:0001501","skeletal system development",-6.7155623859,{"v":1.92503049681095e-7,"d":"1.93E-07"},{"v":-3.8985663655,"d":"-3.899"},10,517,0.0193423597678917,"COL1A1,COL1A2,COL3A1,COL5A2,VCAN,MMP9,TYROBP,SULF1,GREM1,OSR1"]
["1_Member","GO Biological Processes","GO:0032963","collagen metabolic process",-6.7133425979,{"v":1.93489499889387e-7,"d":"1.93E-07"},{"v":-3.8985663655,"d":"-3.899"},6,113,0.0530973451327434,"COL1A1,COL1A2,COL5A1,ID1,MMP9,MMP11"]
["1_Member","Reactome Gene Sets","R-HSA-3000171","Non-integrin membrane-ECM interactions",-6.685307073,{"v":2.06392032073866e-7,"d":"2.06E-07"},{"v":-3.8953544244,"d":"-3.895"},5,59,0.0847457627118644,"COL1A1,COL1A2,COL3A1,COL5A1,COL5A2"]
["1_Member","GO Biological Processes","GO:0009611","response to wounding",-6.4040775337,{"v":3.94386886710743e-7,"d":"3.94E-07"},{"v":-3.637605981,"d":"-3.638"},11,708,0.0155367231638418,"APOE,COL1A1,COL1A2,COL3A1,COL5A1,FCER1G,SERPINE2,S100A8,SPP1,TYROBP,POSTN"]
["1_Member","Reactome Gene Sets","R-HSA-6806834","Signaling by MET",-6.0466611757,{"v":8.98129216312003e-7,"d":"8.98E-07"},{"v":-3.3438587028,"d":"-3.344"},5,79,0.0632911392405063,"COL1A1,COL1A2,COL3A1,COL5A1,COL5A2"]
["1_Member","KEGG Pathway","ko04512","ECM-receptor interaction",-5.9658477719,{"v":1.08181307997186e-6,"d":"1.08E-06"},{"v":-3.2728051364,"d":"-3.273"},5,82,0.0609756097560976,"COL1A1,COL1A2,COL6A3,SPP1,THBS2"]
["1_Member","KEGG Pathway","hsa04512","ECM-receptor interaction",-5.862816011,{"v":1.3714626637157e-6,"d":"1.37E-06"},{"v":-3.1793186933,"d":"-3.179"},5,86,0.0581395348837209,"COL1A1,COL1A2,COL6A3,SPP1,THBS2"]
["1_Member","GO Biological Processes","GO:0030168","platelet activation",-5.8405407278,{"v":1.44364121438798e-6,"d":"1.44E-06"},{"v":-3.1663834364,"d":"-3.166"},6,159,0.0377358490566038,"APOE,COL1A1,COL1A2,COL3A1,FCER1G,SERPINE2"]
["1_Member","Reactome Gene Sets","R-HSA-2173782","Binding and Uptake of Ligands by Scavenger Receptors",-5.6398558805,{"v":2.29162799742251e-6,"d":"2.29E-06"},{"v":-3.0494755868,"d":"-3.049"},4,42,0.0952380952380952,"APOE,COL1A1,COL1A2,COL3A1"]
["1_Member","Reactome Gene Sets","R-HSA-419037","NCAM1 interactions",-5.6398558805,{"v":2.29162799742251e-6,"d":"2.29E-06"},{"v":-3.0494755868,"d":"-3.049"},4,42,0.0952380952380952,"COL3A1,COL5A1,COL5A2,COL6A3"]
["1_Member","Reactome Gene Sets","R-HSA-75892","Platelet Adhesion to exposed collagen",-5.3355059103,{"v":4.61842706649553e-6,"d":"4.62E-06"},{"v":-2.7816424504,"d":"-2.782"},3,15,0.2,"COL1A1,COL1A2,FCER1G"]
["1_Member","GO Biological Processes","GO:0042060","wound healing",-5.2192719024,{"v":6.03570628518409e-6,"d":"6.04E-06"},{"v":-2.6859301097,"d":"-2.686"},9,593,0.015177065767285,"APOE,COL1A1,COL1A2,COL3A1,COL5A1,FCER1G,SERPINE2,S100A8,POSTN"]
["1_Member","GO Biological Processes","GO:0071229","cellular response to acid chemical",-5.1434296246,{"v":7.18737617030931e-6,"d":"7.19E-06"},{"v":-2.636023566,"d":"-2.636"},6,210,0.0285714285714286,"COL1A1,COL1A2,COL3A1,COL5A2,TESC,OSR1"]
["1_Member","Reactome Gene Sets","R-HSA-375165","NCAM signaling for neurite out-growth",-4.9289024525,{"v":1.17787050697747e-5,"d":"1.18E-05"},{"v":-2.4577085665,"d":"-2.458"},4,63,0.0634920634920635,"COL3A1,COL5A1,COL5A2,COL6A3"]
["1_Member","GO Biological Processes","GO:0071230","cellular response to amino acid stimulus",-4.771451528,{"v":1.69257714396079e-5,"d":"1.69E-05"},{"v":-2.3282863656,"d":"-2.328"},4,69,0.0579710144927536,"COL1A1,COL1A2,COL3A1,COL5A2"]
["1_Member","GO Biological Processes","GO:0097435","supramolecular fiber organization",-4.5556961034,{"v":2.78165904664798e-5,"d":"2.78E-05"},{"v":-2.1588309607,"d":"-2.159"},9,719,0.0125173852573018,"APOE,COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,ID1,MMP11,GREM1"]
["1_Member","GO Biological Processes","GO:0031214","biomineral tissue development",-4.5065283288,{"v":3.11509769316686e-5,"d":"3.12E-05"},{"v":-2.1145156889,"d":"-2.115"},5,163,0.0306748466257669,"COL1A1,COL1A2,SPP1,GREM1,OSR1"]
["1_Member","KEGG Pathway","ko05146","Amoebiasis",-4.2062154088,{"v":6.21991702571863e-5,"d":"6.22E-05"},{"v":-1.8511863352,"d":"-1.851"},4,96,0.0416666666666667,"COL1A1,COL1A2,COL3A1,CXCL8"]
["1_Member","Reactome Gene Sets","R-HSA-114604","GPVI-mediated activation cascade",-4.1913268121,{"v":6.43684702324302e-5,"d":"6.44E-05"},{"v":-1.8407068573,"d":"-1.841"},3,35,0.0857142857142857,"COL1A1,COL1A2,FCER1G"]
["1_Member","KEGG Pathway","ko04933","AGE-RAGE signaling pathway in diabetic complications",-4.1540701942,{"v":7.01341932681644e-5,"d":"7.01E-05"},{"v":-1.8121364186,"d":"-1.812"},4,99,0.0404040404040404,"COL1A1,COL1A2,COL3A1,CXCL8"]
["1_Member","KEGG Pathway","ko04510","Focal adhesion",-4.0947615448,{"v":8.03967430103231e-5,"d":"8.04E-05"},{"v":-1.7655397347,"d":"-1.766"},5,199,0.0251256281407035,"COL1A1,COL1A2,COL6A3,SPP1,THBS2"]
["1_Member","KEGG Pathway","hsa04933","AGE-RAGE signaling pathway in diabetic complications",-4.0228031496,{"v":9.48848445443271e-5,"d":"9.49E-05"},{"v":-1.7179406854,"d":"-1.718"},4,107,0.0373831775700935,"COL1A1,COL1A2,COL3A1,CXCL8"]
["1_Member","KEGG Pathway","hsa05146","Amoebiasis",-4.0228031496,{"v":9.48848445443271e-5,"d":"9.49E-05"},{"v":-1.7179406854,"d":"-1.718"},4,107,0.0373831775700935,"COL1A1,COL1A2,COL3A1,CXCL8"]
["1_Member","GO Biological Processes","GO:0007596","blood coagulation",-3.9448478444,{"v":0.000113540853775933,"d":"1.14E-04"},{"v":-1.6777739411,"d":"-1.678"},6,344,0.0174418604651163,"APOE,COL1A1,COL1A2,COL3A1,FCER1G,SERPINE2"]
["1_Member","KEGG Pathway","hsa04510","Focal adhesion",-3.9369409536,{"v":0.000115626943715896,"d":"1.16E-04"},{"v":-1.6734711746,"d":"-1.673"},5,215,0.0232558139534884,"COL1A1,COL1A2,COL6A3,SPP1,THBS2"]
["1_Member","GO Biological Processes","GO:0001101","response to acid chemical",-3.9242870332,{"v":0.000119045495442186,"d":"1.19E-04"},{"v":-1.6720226018,"d":"-1.672"},6,347,0.0172910662824208,"COL1A1,COL1A2,COL3A1,COL5A2,TESC,OSR1"]
["1_Member","Canonical Pathways","M53","PID INTEGRIN3 PATHWAY",-3.9213677382,{"v":0.000119848405880572,"d":"1.20E-04"},{"v":-1.6720226018,"d":"-1.672"},3,43,0.0697674418604651,"COL1A1,COL1A2,SPP1"]
["1_Member","GO Biological Processes","GO:0043200","response to amino acid",-3.9162128851,{"v":0.000121279420992197,"d":"1.21E-04"},{"v":-1.6703282809,"d":"-1.670"},4,114,0.0350877192982456,"COL1A1,COL1A2,COL3A1,COL5A2"]
["1_Member","GO Biological Processes","GO:0007599","hemostasis",-3.9106897924,{"v":0.000122831627890172,"d":"1.23E-04"},{"v":-1.668238364,"d":"-1.668"},6,349,0.0171919770773639,"APOE,COL1A1,COL1A2,COL3A1,FCER1G,SERPINE2"]
["1_Member","GO Biological Processes","GO:0050817","coagulation",-3.9039237812,{"v":0.000124760244960088,"d":"1.25E-04"},{"v":-1.6648786015,"d":"-1.665"},6,350,0.0171428571428571,"APOE,COL1A1,COL1A2,COL3A1,FCER1G,SERPINE2"]
["1_Member","GO Biological Processes","GO:0050878","regulation of body fluid levels",-3.8472281344,{"v":0.000142158183562368,"d":"1.42E-04"},{"v":-1.6182442807,"d":"-1.618"},7,516,0.0135658914728682,"APOE,COL1A1,COL1A2,COL3A1,FCER1G,SERPINE2,CYP4F12"]
["1_Member","KEGG Pathway","hsa04611","Platelet activation",-3.7095189849,{"v":0.000195200540153529,"d":"1.95E-04"},{"v":-1.503142922,"d":"-1.503"},4,129,0.0310077519379845,"COL1A1,COL1A2,COL3A1,FCER1G"]
["1_Member","Reactome Gene Sets","R-HSA-198933","Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell",-3.6712649439,{"v":0.000213174403341149,"d":"2.13E-04"},{"v":-1.4742289072,"d":"-1.474"},4,132,0.0303030303030303,"COL1A1,COL1A2,COL3A1,TYROBP"]
["1_Member","KEGG Pathway","hsa04926","relaxin signaling pathway",-3.6216807451,{"v":0.000238956723595446,"d":"2.39E-04"},{"v":-1.4485842741,"d":"-1.449"},4,136,0.0294117647058824,"COL1A1,COL1A2,COL3A1,MMP9"]
["1_Member","KEGG Pathway","ko04151","PI3K-Akt signaling pathway",-3.0145562293,{"v":0.000967038513410619,"d":"9.67E-04"},{"v":-0.9693310756,"d":"-0.969"},5,342,0.0146198830409357,"COL1A1,COL1A2,COL6A3,SPP1,THBS2"]
["1_Member","KEGG Pathway","hsa05165","human papillomavirus infection",-2.9589307796,{"v":0.0010991810193849,"d":"1.10E-03"},{"v":-0.9307389652,"d":"-0.931"},5,352,0.0142045454545455,"COL1A1,COL1A2,COL6A3,SPP1,THBS2"]
["1_Member","Reactome Gene Sets","R-HSA-422475","Axon guidance",-2.8598565553,{"v":0.00138084027203355,"d":"1.38E-03"},{"v":-0.8560240867,"d":"-0.856"},6,552,0.0108695652173913,"COL3A1,COL5A1,COL5A2,COL6A3,MMP9,TYROBP"]
["1_Member","KEGG Pathway","hsa04151","PI3K-Akt signaling pathway",-2.8122985491,{"v":0.00154064099874463,"d":"1.54E-03"},{"v":-0.8277712358,"d":"-0.828"},5,380,0.0131578947368421,"COL1A1,COL1A2,COL6A3,SPP1,THBS2"]
["1_Member","Reactome Gene Sets","R-HSA-9675108","Nervous system development",-2.7624619366,{"v":0.00172797742110013,"d":"1.73E-03"},{"v":-0.7891187902,"d":"-0.789"},6,577,0.0103986135181976,"COL3A1,COL5A1,COL5A2,COL6A3,MMP9,TYROBP"]
["1_Member","GO Biological Processes","GO:0030282","bone mineralization",-2.6480656008,{"$f":"10^(E67)","v":{"v":0.00224871490859106,"d":"2.25E-03"}},{"v":-0.7032109922,"d":"-0.703"},3,117,{"$f":"H67/I67","v":0.0256410256410256},"COL1A2,GREM1,OSR1"]
["1_Member","GO Biological Processes","GO:0043588","skin development",-2.6009484977,{"v":0.00250640646621209,"d":"2.51E-03"},{"v":-0.6612335288,"d":"-0.661"},5,425,0.0117647058823529,"COL1A1,COL1A2,COL3A1,COL5A1,COL5A2"]
["1_Member","GO Biological Processes","GO:0042476","odontogenesis",-2.4998253664,{"v":0.00316354949529441,"d":"3.16E-03"},{"v":-0.576816091,"d":"-0.577"},3,132,0.0227272727272727,"COL1A1,COL1A2,OSR1"]
["1_Member","Reactome Gene Sets","R-HSA-202733","Cell surface interactions at the vascular wall",-2.4544200528,{"v":0.00351220573085994,"d":"3.51E-03"},{"v":-0.5346761648,"d":"-0.535"},3,137,0.0218978102189781,"COL1A1,COL1A2,FCER1G"]
["1_Member","GO Biological Processes","GO:0007266","Rho protein signal transduction",-2.4193697922,{"v":0.00380741492325829,"d":"3.81E-03"},{"v":-0.504478407,"d":"-0.504"},3,141,0.0212765957446809,"APOE,COL1A2,COL3A1"]
["2_Summary","GO Biological Processes","GO:0001568","blood vessel development",-8.7948576558,{"v":1.60377095593573e-9,"d":"1.60E-09"},{"v":-5.6790514278,"d":"-5.679"},14,794,0.017632241813602,"APOE,COL1A1,COL1A2,COL3A1,COL5A1,HPGD,ID1,CXCL8,CXCL10,SMAD6,THBS2,SULF1,GREM1,OSR1,MT1G,POSTN,S100A8"]
["2_Member","GO Biological Processes","GO:0001568","blood vessel development",-8.7948576558,{"v":1.60377095593573e-9,"d":"1.60E-09"},{"v":-5.6790514278,"d":"-5.679"},14,794,0.017632241813602,"APOE,COL1A1,COL1A2,COL3A1,COL5A1,HPGD,ID1,CXCL8,CXCL10,SMAD6,THBS2,SULF1,GREM1,OSR1"]
["2_Member","GO Biological Processes","GO:0071363","cellular response to growth factor stimulus",-6.3380057389,{"v":4.59191944894093e-7,"d":"4.59E-07"},{"v":-3.5828151966,"d":"-3.583"},11,719,0.0152990264255911,"COL1A1,COL1A2,COL3A1,HPGD,ID1,CXCL8,SMAD6,MT1G,POSTN,SULF1,GREM1"]
["2_Member","GO Biological Processes","GO:0070848","response to growth factor",-6.1634833956,{"v":6.86304117405334e-7,"d":"6.86E-07"},{"v":-3.430012103,"d":"-3.430"},11,749,0.0146862483311081,"COL1A1,COL1A2,COL3A1,HPGD,ID1,CXCL8,SMAD6,MT1G,POSTN,SULF1,GREM1"]
["2_Member","GO Biological Processes","GO:0071560","cellular response to transforming growth factor beta stimulus",-5.8017868264,{"v":1.57838583083014e-6,"d":"1.58E-06"},{"v":-3.1457277571,"d":"-3.146"},7,256,0.02734375,"COL1A1,COL1A2,COL3A1,HPGD,ID1,SMAD6,POSTN"]
["2_Member","GO Biological Processes","GO:0071559","response to transforming growth factor beta",-5.7350157715,{"v":1.84070515464108e-6,"d":"1.84E-06"},{"v":-3.0963307982,"d":"-3.096"},7,262,0.0267175572519084,"COL1A1,COL1A2,COL3A1,HPGD,ID1,SMAD6,POSTN"]
["2_Member","GO Biological Processes","GO:0007178","transmembrane receptor protein serine/threonine kinase signaling pathway",-4.8018202018,{"v":1.57826453701566e-5,"d":"1.58E-05"},{"v":-2.3531921437,"d":"-2.353"},7,364,0.0192307692307692,"COL1A2,COL3A1,HPGD,ID1,SMAD6,SULF1,GREM1"]
["2_Member","GO Biological Processes","GO:0007179","transforming growth factor beta receptor signaling pathway",-4.0240811352,{"v":9.46060401186757e-5,"d":"9.46E-05"},{"v":-1.7179406854,"d":"-1.718"},5,206,0.0242718446601942,"COL1A2,COL3A1,HPGD,ID1,SMAD6"]
["2_Member","GO Biological Processes","GO:0031589","cell-substrate adhesion",-3.8374301035,{"v":0.000145401838033251,"d":"1.45E-04"},{"v":-1.6117488853,"d":"-1.612"},6,360,0.0166666666666667,"COL1A1,COL3A1,ID1,SMAD6,POSTN,GREM1"]
["2_Member","GO Biological Processes","GO:0032355","response to estradiol",-2.4193697922,{"v":0.00380741492325829,"d":"3.81E-03"},{"v":-0.504478407,"d":"-0.504"},3,141,0.0212765957446809,"COL1A1,HPGD,POSTN"]
["2_Member","GO Biological Processes","GO:0046677","response to antibiotic",-2.2272131777,{"v":0.0059263435279623,"d":"5.93E-03"},{"v":-0.3478256487,"d":"-0.348"},4,326,0.0122699386503067,"COL1A1,HPGD,ID1,S100A8"]
["3_Summary","GO Biological Processes","GO:0045596","negative regulation of cell differentiation",-7.9376945584,{"v":1.15426477291969e-8,"d":"1.15E-08"},{"v":-4.9338620899,"d":"-4.934"},13,772,0.016839378238342,"APOE,COL3A1,COL5A1,COL5A2,ID1,CXCL10,SMAD6,MMP9,MMP11,SPP1,POSTN,GREM1,OSR1,HPGD,SULF1,CTHRC1,COL1A1,TYROBP"]
["3_Member","GO Biological Processes","GO:0045596","negative regulation of cell differentiation",-7.9376945584,{"v":1.15426477291969e-8,"d":"1.15E-08"},{"v":-4.9338620899,"d":"-4.934"},13,772,0.016839378238342,"APOE,COL3A1,COL5A1,COL5A2,ID1,CXCL10,SMAD6,MMP9,MMP11,SPP1,POSTN,GREM1,OSR1"]
["3_Member","GO Biological Processes","GO:0001822","kidney development",-4.4037059449,{"v":3.94724474382318e-5,"d":"3.95E-05"},{"v":-2.0212386229,"d":"-2.021"},6,284,0.0211267605633803,"HPGD,SMAD6,MMP9,SULF1,GREM1,OSR1"]
["3_Member","GO Biological Processes","GO:0072001","renal system development",-4.3283928904,{"v":4.69469204746042e-5,"d":"4.69E-05"},{"v":-1.9644089741,"d":"-1.964"},6,293,0.0204778156996587,"HPGD,SMAD6,MMP9,SULF1,GREM1,OSR1"]
["3_Member","GO Biological Processes","GO:0001655","urogenital system development",-4.0363146206,{"v":9.19783002092116e-5,"d":"9.20E-05"},{"v":-1.719443249,"d":"-1.719"},6,331,0.0181268882175227,"HPGD,SMAD6,MMP9,SULF1,GREM1,OSR1"]
["3_Member","GO Biological Processes","GO:0030278","regulation of ossification",-3.9655402541,{"v":0.00010825793678293,"d":"1.08E-04"},{"v":-1.6948320661,"d":"-1.695"},5,212,0.0235849056603774,"ID1,SMAD6,GREM1,CTHRC1,OSR1"]
["3_Member","GO Biological Processes","GO:0035850","epithelial cell differentiation involved in kidney development",-3.8055406491,{"v":0.000156480185002849,"d":"1.56E-04"},{"v":-1.5866796684,"d":"-1.587"},3,47,0.0638297872340425,"MMP9,GREM1,OSR1"]
["3_Member","GO Biological Processes","GO:0045667","regulation of osteoblast differentiation",-3.6839121695,{"v":0.000207056005071817,"d":"2.07E-04"},{"v":-1.4837850559,"d":"-1.484"},4,131,0.0305343511450382,"ID1,SMAD6,GREM1,CTHRC1"]
["3_Member","GO Biological Processes","GO:0045668","negative regulation of osteoblast differentiation",-3.6498670965,{"v":0.000223940634047116,"d":"2.24E-04"},{"v":-1.4619744393,"d":"-1.462"},3,53,0.0566037735849057,"ID1,SMAD6,GREM1"]
["3_Member","GO Biological Processes","GO:0090183","regulation of kidney development",-3.5788250889,{"v":0.000263739337604764,"d":"2.64E-04"},{"v":-1.4172613703,"d":"-1.417"},3,56,0.0535714285714286,"MMP9,GREM1,OSR1"]
["3_Member","GO Biological Processes","GO:0061005","cell differentiation involved in kidney development",-3.5560282433,{"v":0.000277953250165181,"d":"2.78E-04"},{"v":-1.4001047921,"d":"-1.400"},3,57,0.0526315789473684,"MMP9,GREM1,OSR1"]
["3_Member","GO Biological Processes","GO:0061448","connective tissue development",-3.5232868831,{"v":0.000299718200816407,"d":"3.00E-04"},{"v":-1.3701563321,"d":"-1.370"},5,264,0.0189393939393939,"COL1A1,COL5A1,SULF1,GREM1,OSR1"]
["3_Member","GO Biological Processes","GO:0016331","morphogenesis of embryonic epithelium",-3.448739,{"v":0.000355845108231926,"d":"3.56E-04"},{"v":-1.3066038333,"d":"-1.307"},4,151,0.0264900662251656,"SULF1,GREM1,CTHRC1,OSR1"]
["3_Member","GO Biological Processes","GO:0030509","BMP signaling pathway",-3.4057319592,{"v":0.000392887345449778,"d":"3.93E-04"},{"v":-1.2743206579,"d":"-1.274"},4,155,0.0258064516129032,"ID1,SMAD6,SULF1,GREM1"]
["3_Member","GO Biological Processes","GO:0071772","response to BMP",-3.2738067233,{"v":0.000532345119325459,"d":"5.32E-04"},{"v":-1.1605476843,"d":"-1.161"},4,168,0.0238095238095238,"ID1,SMAD6,SULF1,GREM1"]
["3_Member","GO Biological Processes","GO:0071773","cellular response to BMP stimulus",-3.2738067233,{"v":0.000532345119325459,"d":"5.32E-04"},{"v":-1.1605476843,"d":"-1.161"},4,168,0.0238095238095238,"ID1,SMAD6,SULF1,GREM1"]
["3_Member","GO Biological Processes","GO:0048729","tissue morphogenesis",-3.1719598825,{"v":0.000673038824672668,"d":"6.73E-04"},{"v":-1.0785577641,"d":"-1.079"},7,668,0.0104790419161677,"COL3A1,COL5A1,CXCL10,SULF1,GREM1,CTHRC1,OSR1"]
["3_Member","GO Biological Processes","GO:1905330","regulation of morphogenesis of an epithelium",-3.1525000173,{"v":0.000703882199897505,"d":"7.04E-04"},{"v":-1.0639234428,"d":"-1.064"},4,181,0.0220994475138122,"CXCL10,SULF1,GREM1,CTHRC1"]
["3_Member","GO Biological Processes","GO:0030279","negative regulation of ossification",-3.0617365155,{"v":0.000867488017198928,"d":"8.67E-04"},{"v":-0.9965147334,"d":"-0.997"},3,84,0.0357142857142857,"ID1,SMAD6,GREM1"]
["3_Member","GO Biological Processes","GO:0051216","cartilage development",-3.0156035617,{"v":0.000964709240170062,"d":"9.65E-04"},{"v":-0.9693310756,"d":"-0.969"},4,197,0.0203045685279188,"COL1A1,SULF1,GREM1,OSR1"]
["3_Member","GO Biological Processes","GO:0060348","bone development",-2.9594900554,{"v":0.00109776642695741,"d":"1.10E-03"},{"v":-0.9307389652,"d":"-0.931"},4,204,0.0196078431372549,"COL1A1,TYROBP,SULF1,GREM1"]
["3_Member","GO Biological Processes","GO:0030510","regulation of BMP signaling pathway",-2.9337378919,{"v":0.00116482882202933,"d":"1.16E-03"},{"v":-0.9076290287,"d":"-0.908"},3,93,0.032258064516129,"SMAD6,SULF1,GREM1"]
["3_Member","GO Biological Processes","GO:0001657","ureteric bud development",-2.8681914531,{"v":0.00135459212630537,"d":"1.35E-03"},{"v":-0.8623804186,"d":"-0.862"},3,98,0.0306122448979592,"SMAD6,GREM1,OSR1"]
["3_Member","GO Biological Processes","GO:0072163","mesonephric epithelium development",-2.8555094102,{"v":0.00139473143656995,"d":"1.39E-03"},{"v":-0.8556072353,"d":"-0.856"},3,99,0.0303030303030303,"SMAD6,GREM1,OSR1"]
["3_Member","GO Biological Processes","GO:0072164","mesonephric tubule development",-2.8555094102,{"v":0.00139473143656995,"d":"1.39E-03"},{"v":-0.8556072353,"d":"-0.856"},3,99,0.0303030303030303,"SMAD6,GREM1,OSR1"]
["3_Member","GO Biological Processes","GO:0002009","morphogenesis of an epithelium",-2.8399618355,{"v":0.00144556679725063,"d":"1.45E-03"},{"v":-0.8439547045,"d":"-0.844"},6,557,0.0107719928186715,"COL5A1,CXCL10,SULF1,GREM1,CTHRC1,OSR1"]
["3_Member","GO Biological Processes","GO:0030111","regulation of Wnt signaling pathway",-2.8324738031,{"v":0.00147070712665267,"d":"1.47E-03"},{"v":-0.8413584683,"d":"-0.841"},5,376,0.0132978723404255,"APOE,COL1A1,SULF1,GREM1,CTHRC1"]
["3_Member","GO Biological Processes","GO:0001823","mesonephros development",-2.8061107558,{"v":0.00156274905228152,"d":"1.56E-03"},{"v":-0.8253435913,"d":"-0.825"},3,103,0.029126213592233,"SMAD6,GREM1,OSR1"]
["3_Member","GO Biological Processes","GO:0002062","chondrocyte differentiation",-2.7357244687,{"v":0.00183770387588837,"d":"1.84E-03"},{"v":-0.7697381558,"d":"-0.770"},3,109,0.0275229357798165,"SULF1,GREM1,OSR1"]
["3_Member","GO Biological Processes","GO:0007507","heart development",-2.7137927688,{"v":0.00193289040943335,"d":"1.93E-03"},{"v":-0.7560898115,"d":"-0.756"},6,590,0.0101694915254237,"COL3A1,COL5A1,ID1,SMAD6,GREM1,OSR1"]
["3_Member","GO Biological Processes","GO:0001838","embryonic epithelial tube formation",-2.5666156323,{"v":0.00271259131984632,"d":"2.71E-03"},{"v":-0.633660247,"d":"-0.634"},3,125,0.024,"GREM1,CTHRC1,OSR1"]
["3_Member","GO Biological Processes","GO:0048706","embryonic skeletal system development",-2.5185107704,{"v":0.00303032514551263,"d":"3.03E-03"},{"v":-0.5922113696,"d":"-0.592"},3,130,0.0230769230769231,"COL1A1,SULF1,OSR1"]
["3_Member","GO Biological Processes","GO:0072175","epithelial tube formation",-2.490597063,{"v":0.00323149089798499,"d":"3.23E-03"},{"v":-0.5692235503,"d":"-0.569"},3,133,0.0225563909774436,"GREM1,CTHRC1,OSR1"]
["3_Member","GO Biological Processes","GO:0072073","kidney epithelium development",-2.4107757147,{"v":0.00388350872578492,"d":"3.88E-03"},{"v":-0.4974898562,"d":"-0.497"},3,142,0.0211267605633803,"SMAD6,GREM1,OSR1"]
["3_Member","GO Biological Processes","GO:0072006","nephron development",-2.3937830933,{"v":0.00403847042450961,"d":"4.04E-03"},{"v":-0.482096848,"d":"-0.482"},3,144,0.0208333333333333,"SULF1,GREM1,OSR1"]
["3_Member","GO Biological Processes","GO:0060828","regulation of canonical Wnt signaling pathway",-2.3796109728,{"v":0.00417242969118826,"d":"4.17E-03"},{"v":-0.4711063863,"d":"-0.471"},4,295,0.0135593220338983,"APOE,COL1A1,GREM1,CTHRC1"]
["3_Member","GO Biological Processes","GO:0035148","tube formation",-2.3443056137,{"v":0.00452578987284933,"d":"4.53E-03"},{"v":-0.4405302334,"d":"-0.441"},3,150,0.02,"GREM1,CTHRC1,OSR1"]
["3_Member","GO Biological Processes","GO:0016055","Wnt signaling pathway",-2.2303031935,{"v":0.00588432710084487,"d":"5.88E-03"},{"v":-0.3486352188,"d":"-0.349"},5,520,0.00961538461538462,"APOE,COL1A1,SULF1,GREM1,CTHRC1"]
["3_Member","GO Biological Processes","GO:0198738","cell-cell signaling by wnt",-2.2233921287,{"v":0.00597871527279962,"d":"5.98E-03"},{"v":-0.3458319692,"d":"-0.346"},5,522,0.00957854406130268,"APOE,COL1A1,SULF1,GREM1,CTHRC1"]
["3_Member","GO Biological Processes","GO:0060562","epithelial tube morphogenesis",-2.2042000874,{"v":0.00624884730637437,"d":"6.25E-03"},{"v":-0.3292366491,"d":"-0.329"},4,331,0.0120845921450151,"CXCL10,GREM1,CTHRC1,OSR1"]
["3_Member","GO Biological Processes","GO:0060070","canonical Wnt signaling pathway",-2.1682044186,{"v":0.00678884012657035,"d":"6.79E-03"},{"v":-0.3011044834,"d":"-0.301"},4,339,0.0117994100294985,"APOE,COL1A1,GREM1,CTHRC1"]
["3_Member","GO Biological Processes","GO:0030336","negative regulation of cell migration",-2.1202915069,{"v":0.00758068573857073,"d":"7.58E-03"},{"v":-0.2667967465,"d":"-0.267"},4,350,0.0114285714285714,"APOE,COL3A1,SULF1,GREM1"]
["3_Member","GO Biological Processes","GO:0090288","negative regulation of cellular response to growth factor stimulus",-2.1125196228,{"v":0.00771756644388059,"d":"7.72E-03"},{"v":-0.2624433155,"d":"-0.262"},3,182,0.0164835164835165,"SMAD6,SULF1,GREM1"]
["3_Member","GO Biological Processes","GO:0090090","negative regulation of canonical Wnt signaling pathway",-2.0995558652,{"v":0.00795140976490664,"d":"7.95E-03"},{"v":-0.2543599781,"d":"-0.254"},3,184,0.016304347826087,"APOE,GREM1,CTHRC1"]
["3_Member","GO Biological Processes","GO:2000146","negative regulation of cell motility",-2.0577183861,{"v":0.00875551333672653,"d":"8.76E-03"},{"v":-0.2220082469,"d":"-0.222"},4,365,0.010958904109589,"APOE,COL3A1,SULF1,GREM1"]
["4_Summary","GO Biological Processes","GO:0006882","cellular zinc ion homeostasis",-7.7292316144,{"v":1.86538459377352e-8,"d":"1.87E-08"},{"v":-4.7631877068,"d":"-4.763"},5,37,0.135135135135135,"MT1G,MT1X,MT2A,S100A8,S100A9,APOE,COL1A1,GPX2,HPGD,DHRS2,MMP9,SERPINE2,SPP1,GREM1,CXCL10,CYP4F12,POSTN,ID1,CXCL8"]
["4_Member","GO Biological Processes","GO:0006882","cellular zinc ion homeostasis",-7.7292316144,{"v":1.86538459377352e-8,"d":"1.87E-08"},{"v":-4.7631877068,"d":"-4.763"},5,37,0.135135135135135,"MT1G,MT1X,MT2A,S100A8,S100A9"]
["4_Member","GO Biological Processes","GO:0055069","zinc ion homeostasis",-7.6098507195,{"v":2.45555282039764e-8,"d":"2.46E-08"},{"v":-4.6785689181,"d":"-4.679"},5,39,0.128205128205128,"MT1G,MT1X,MT2A,S100A8,S100A9"]
["4_Member","GO Biological Processes","GO:0009636","response to toxic substance",-6.6694570406,{"$f":"10^(E131)","v":{"v":2.14063666309891e-7,"d":"2.14E-07"}},{"v":-3.8914036154,"d":"-3.891"},10,523,{"$f":"H131/I131","v":0.0191204588910134},"APOE,COL1A1,GPX2,HPGD,MT1G,MT1X,MT2A,S100A8,S100A9,DHRS2"]
["4_Member","GO Biological Processes","GO:0098754","detoxification",-6.2946648889,{"v":5.07382064339471e-7,"d":"5.07E-07"},{"v":-3.5504697309,"d":"-3.550"},6,133,0.0451127819548872,"APOE,GPX2,MT1G,MT1X,MT2A,S100A9"]
["4_Member","GO Biological Processes","GO:0071276","cellular response to cadmium ion",-5.8177796867,{"v":1.5213190841563e-6,"d":"1.52E-06"},{"v":-3.1527657747,"d":"-3.153"},4,38,0.105263157894737,"MMP9,MT1G,MT1X,MT2A"]
["4_Member","Reactome Gene Sets","R-HSA-5661231","Metallothioneins bind metals",-5.773286963,{"v":1.68543899222637e-6,"d":"1.69E-06"},{"v":-3.126001818,"d":"-3.126"},3,11,0.272727272727273,"MT1G,MT1X,MT2A"]
["4_Member","Reactome Gene Sets","R-HSA-5660526","Response to metal ions",-5.4317294032,{"v":3.7005868122435e-6,"d":"3.70E-06"},{"v":-2.8563262655,"d":"-2.856"},3,14,0.214285714285714,"MT1G,MT1X,MT2A"]
["4_Member","GO Biological Processes","GO:0010273","detoxification of copper ion",-5.3355059103,{"v":4.61842706649553e-6,"d":"4.62E-06"},{"v":-2.7816424504,"d":"-2.782"},3,15,0.2,"MT1G,MT1X,MT2A"]
["4_Member","GO Biological Processes","GO:1990169","stress response to copper ion",-5.3355059103,{"v":4.61842706649553e-6,"d":"4.62E-06"},{"v":-2.7816424504,"d":"-2.782"},3,15,0.2,"MT1G,MT1X,MT2A"]
["4_Member","GO Biological Processes","GO:0046916","cellular transition metal ion homeostasis",-5.2586050949,{"v":5.51308775055399e-6,"d":"5.51E-06"},{"v":-2.711690495,"d":"-2.712"},5,114,0.043859649122807,"MT1G,MT1X,MT2A,S100A8,S100A9"]
["4_Member","GO Biological Processes","GO:0010043","response to zinc ion",-5.1974018756,{"v":6.34743298542743e-6,"d":"6.35E-06"},{"v":-2.6706906618,"d":"-2.671"},4,54,0.0740740740740741,"MT1G,MT1X,MT2A,S100A8"]
["4_Member","GO Biological Processes","GO:0061687","detoxification of inorganic compound",-5.1623812743,{"v":6.88047982424509e-6,"d":"6.88E-06"},{"v":-2.6486350377,"d":"-2.649"},3,17,0.176470588235294,"MT1G,MT1X,MT2A"]
["4_Member","GO Biological Processes","GO:0097501","stress response to metal ion",-5.1623812743,{"v":6.88047982424509e-6,"d":"6.88E-06"},{"v":-2.6486350377,"d":"-2.649"},3,17,0.176470588235294,"MT1G,MT1X,MT2A"]
["4_Member","GO Biological Processes","GO:0046686","response to cadmium ion",-4.9015925525,{"v":1.25431740178296e-5,"d":"1.25E-05"},{"v":-2.4361509954,"d":"-2.436"},4,64,0.0625,"MMP9,MT1G,MT1X,MT2A"]
["4_Member","GO Biological Processes","GO:0055076","transition metal ion homeostasis",-4.88531018,{"v":1.30223636838792e-5,"d":"1.30E-05"},{"v":-2.4255457558,"d":"-2.426"},5,136,0.0367647058823529,"MT1G,MT1X,MT2A,S100A8,S100A9"]
["4_Member","GO Biological Processes","GO:0040008","regulation of growth",-4.7008084865,{"v":1.99155137199429e-5,"d":"1.99E-05"},{"v":-2.271507212,"d":"-2.272"},9,689,0.0130624092888244,"APOE,MT1G,MT1X,MT2A,SERPINE2,S100A8,S100A9,SPP1,GREM1"]
["4_Member","GO Biological Processes","GO:0071294","cellular response to zinc ion",-4.6934830753,{"v":2.02542853737522e-5,"d":"2.03E-05"},{"v":-2.271507212,"d":"-2.272"},3,24,0.125,"MT1G,MT1X,MT2A"]
["4_Member","GO Biological Processes","GO:0045926","negative regulation of growth",-4.6750356224,{"v":2.11331569095123e-5,"d":"2.11E-05"},{"v":-2.2581993987,"d":"-2.258"},6,254,0.0236220472440945,"MT1G,MT1X,MT2A,SERPINE2,SPP1,GREM1"]
["4_Member","GO Biological Processes","GO:0071280","cellular response to copper ion",-4.487093309,{"v":3.25766701883646e-5,"d":"3.26E-05"},{"v":-2.099879552,"d":"-2.100"},3,28,0.107142857142857,"MT1G,MT1X,MT2A"]
["4_Member","GO Biological Processes","GO:0055065","metal ion homeostasis",-4.0103201451,{"v":9.76517104915002e-5,"d":"9.77E-05"},{"v":-1.7132830184,"d":"-1.713"},8,657,0.0121765601217656,"APOE,CXCL10,MT1G,MT1X,MT2A,S100A8,S100A9,CYP4F12"]
["4_Member","GO Biological Processes","GO:0016049","cell growth",-3.9694754767,{"v":0.000107281422470996,"d":"1.07E-04"},{"v":-1.6948320661,"d":"-1.695"},7,493,0.0141987829614604,"APOE,SERPINE2,S100A8,S100A9,SPP1,POSTN,GREM1"]
["4_Member","GO Biological Processes","GO:0072503","cellular divalent inorganic cation homeostasis",-3.9694754767,{"v":0.000107281422470996,"d":"1.07E-04"},{"v":-1.6948320661,"d":"-1.695"},7,493,0.0141987829614604,"APOE,CXCL10,MT1G,MT1X,MT2A,S100A8,S100A9"]
["4_Member","GO Biological Processes","GO:0046688","response to copper ion",-3.9213677382,{"v":0.000119848405880572,"d":"1.20E-04"},{"v":-1.6720226018,"d":"-1.672"},3,43,0.0697674418604651,"MT1G,MT1X,MT2A"]
["4_Member","GO Biological Processes","GO:0072507","divalent inorganic cation homeostasis",-3.8680336484,{"v":0.000135508441864086,"d":"1.36E-04"},{"v":-1.6323682094,"d":"-1.632"},7,512,0.013671875,"APOE,CXCL10,MT1G,MT1X,MT2A,S100A8,S100A9"]
["4_Member","KEGG Pathway","ko04978","Mineral absorption",-3.6996112325,{"v":0.000199704921410461,"d":"2.00E-04"},{"v":-1.4963708834,"d":"-1.496"},3,51,0.0588235294117647,"MT1G,MT1X,MT2A"]
["4_Member","GO Biological Processes","GO:0055080","cation homeostasis",-3.6610770413,{"v":0.000218234274266975,"d":"2.18E-04"},{"v":-1.4671102364,"d":"-1.467"},8,739,0.0108254397834912,"APOE,CXCL10,MT1G,MT1X,MT2A,S100A8,S100A9,CYP4F12"]
["4_Member","KEGG Pathway","hsa04978","Mineral absorption",-3.6498670965,{"v":0.000223940634047116,"d":"2.24E-04"},{"v":-1.4619744393,"d":"-1.462"},3,53,0.0566037735849057,"MT1G,MT1X,MT2A"]
["4_Member","GO Biological Processes","GO:0098771","inorganic ion homeostasis",-3.6216531551,{"v":0.000238971904597504,"d":"2.39E-04"},{"v":-1.4485842741,"d":"-1.449"},8,749,0.0106809078771696,"APOE,CXCL10,MT1G,MT1X,MT2A,S100A8,S100A9,CYP4F12"]
["4_Member","GO Biological Processes","GO:0006875","cellular metal ion homeostasis",-3.5107192557,{"v":0.000308518168333459,"d":"3.09E-04"},{"v":-1.3603637587,"d":"-1.360"},7,586,0.0119453924914676,"APOE,CXCL10,MT1G,MT1X,MT2A,S100A8,S100A9"]
["4_Member","GO Biological Processes","GO:0001558","regulation of cell growth",-3.4613071661,{"v":0.000345694789683908,"d":"3.46E-04"},{"v":-1.3164491411,"d":"-1.316"},6,423,0.0141843971631206,"APOE,SERPINE2,S100A8,S100A9,SPP1,GREM1"]
["4_Member","GO Biological Processes","GO:0030003","cellular cation homeostasis",-3.187310724,{"v":0.000649664709420384,"d":"6.50E-04"},{"v":-1.091475577,"d":"-1.091"},7,664,0.0105421686746988,"APOE,CXCL10,MT1G,MT1X,MT2A,S100A8,S100A9"]
["4_Member","GO Biological Processes","GO:0006873","cellular ion homeostasis",-3.1378204915,{"v":0.000728080682557864,"d":"7.28E-04"},{"v":-1.0540164318,"d":"-1.054"},7,677,0.0103397341211226,"APOE,CXCL10,MT1G,MT1X,MT2A,S100A8,S100A9"]
["4_Member","GO Biological Processes","GO:0071248","cellular response to metal ion",-3.0486579704,{"v":0.000894009285588375,"d":"8.94E-04"},{"v":-0.9861163046,"d":"-0.986"},4,193,0.0207253886010363,"MMP9,MT1G,MT1X,MT2A"]
["4_Member","GO Biological Processes","GO:0010038","response to metal ion",-2.8840092164,{"v":0.00130614316946135,"d":"1.31E-03"},{"v":-0.870192527,"d":"-0.870"},5,366,0.0136612021857923,"MMP9,MT1G,MT1X,MT2A,S100A8"]
["4_Member","GO Biological Processes","GO:0071241","cellular response to inorganic substance",-2.8315877605,{"v":0.00147371070928913,"d":"1.47E-03"},{"v":-0.8413584683,"d":"-0.841"},4,221,0.0180995475113122,"MMP9,MT1G,MT1X,MT2A"]
["4_Member","GO Biological Processes","GO:0010035","response to inorganic substance",-2.7969330528,{"v":0.00159612517356236,"d":"1.60E-03"},{"v":-0.8189888179,"d":"-0.819"},6,568,0.0105633802816901,"COL1A1,MMP9,MT1G,MT1X,MT2A,S100A8"]
["4_Member","Reactome Gene Sets","R-HSA-8953897","Cellular responses to external stimuli",-2.6844794752,{"v":0.00206785710674076,"d":"2.07E-03"},{"v":-0.7309212791,"d":"-0.731"},6,598,0.0100334448160535,"GPX2,ID1,CXCL8,MT1G,MT1X,MT2A"]
["5_Summary","GO Biological Processes","GO:0001503","ossification",-7.6236404998,{"v":2.37880860155869e-8,"d":"2.38E-08"},{"v":-4.6785689181,"d":"-4.679"},10,413,0.0242130750605327,"COL1A1,COL1A2,COL5A2,VCAN,ID1,SMAD6,SPP1,GREM1,CTHRC1,OSR1,THBS2,POSTN,SERPINE2"]
["5_Member","GO Biological Processes","GO:0001503","ossification",-7.6236404998,{"v":2.37880860155869e-8,"d":"2.38E-08"},{"v":-4.6785689181,"d":"-4.679"},10,413,0.0242130750605327,"COL1A1,COL1A2,COL5A2,VCAN,ID1,SMAD6,SPP1,GREM1,CTHRC1,OSR1"]
["5_Member","GO Biological Processes","GO:0001649","osteoblast differentiation",-6.0868515144,{"v":8.18744669685709e-7,"d":"8.19E-07"},{"v":-3.3638456555,"d":"-3.364"},7,232,0.0301724137931034,"COL1A1,VCAN,ID1,SMAD6,SPP1,GREM1,CTHRC1"]
["5_Member","Canonical Pathways","M3008","NABA ECM GLYCOPROTEINS",-3.0237978476,{"v":0.000946677711837477,"d":"9.47E-04"},{"v":-0.9720089244,"d":"-0.972"},4,196,0.0204081632653061,"SPP1,THBS2,POSTN,CTHRC1"]
["5_Member","GO Biological Processes","GO:0046849","bone remodeling",-2.9610115847,{"v":0.00109392718564047,"d":"1.09E-03"},{"v":-0.9307389652,"d":"-0.931"},3,91,0.032967032967033,"SPP1,GREM1,CTHRC1"]
["5_Member","GO Biological Processes","GO:0048771","tissue remodeling",-2.1125196228,{"v":0.00771756644388059,"d":"7.72E-03"},{"v":-0.2624433155,"d":"-0.262"},3,182,0.0164835164835165,"SPP1,GREM1,CTHRC1"]
["5_Member","GO Biological Processes","GO:0030308","negative regulation of cell growth",-2.0615837125,{"v":0.00867793289540423,"d":"8.68E-03"},{"v":-0.2245310854,"d":"-0.225"},3,190,0.0157894736842105,"SERPINE2,SPP1,GREM1"]
["6_Summary","Reactome Gene Sets","R-HSA-211935","Fatty acids",-7.5342337082,{"v":2.92257921822335e-8,"d":"2.92E-08"},{"v":-4.619342323,"d":"-4.619"},4,15,0.266666666666667,"CYP2J2,CYP4B1,CYP4F12,CYP4F22,GPX2,HPGD,HMGCS2,FABP6"]
["6_Member","Reactome Gene Sets","R-HSA-211935","Fatty acids",-7.5342337082,{"v":2.92257921822335e-8,"d":"2.92E-08"},{"v":-4.619342323,"d":"-4.619"},4,15,0.266666666666667,"CYP2J2,CYP4B1,CYP4F12,CYP4F22"]
["6_Member","Reactome Gene Sets","R-HSA-2142753","Arachidonic acid metabolism",-6.685307073,{"v":2.06392032073866e-7,"d":"2.06E-07"},{"v":-3.8953544244,"d":"-3.895"},5,59,0.0847457627118644,"CYP2J2,CYP4B1,GPX2,HPGD,CYP4F22"]
["6_Member","Reactome Gene Sets","R-HSA-211979","Eicosanoids",-5.6490349062,{"v":2.24370158015218e-6,"d":"2.24E-06"},{"v":-3.0494755868,"d":"-3.049"},3,12,0.25,"CYP4B1,CYP4F12,CYP4F22"]
["6_Member","Reactome Gene Sets","R-HSA-211897","Cytochrome P450 - arranged by substrate type",-4.8482943423,{"v":1.41809608386229e-5,"d":"1.42E-05"},{"v":-2.3941337956,"d":"-2.394"},4,66,0.0606060606060606,"CYP2J2,CYP4B1,CYP4F12,CYP4F22"]
["6_Member","GO Biological Processes","GO:1901568","fatty acid derivative metabolic process",-4.3592392411,{"v":4.37281152421048e-5,"d":"4.37E-05"},{"v":-1.9861119454,"d":"-1.986"},5,175,0.0285714285714286,"CYP2J2,HMGCS2,HPGD,CYP4F12,CYP4F22"]
["6_Member","Reactome Gene Sets","R-HSA-8978868","Fatty acid metabolism",-4.3357481834,{"v":4.61585137500107e-5,"d":"4.62E-05"},{"v":-1.9672166393,"d":"-1.967"},5,177,0.0282485875706215,"CYP2J2,CYP4B1,GPX2,HPGD,CYP4F22"]
["6_Member","Reactome Gene Sets","R-HSA-211945","Phase I - Functionalization of compounds",-4.0386321857,{"v":9.14887753591079e-5,"d":"9.15E-05"},{"v":-1.719443249,"d":"-1.719"},4,106,0.0377358490566038,"CYP2J2,CYP4B1,CYP4F12,CYP4F22"]
["6_Member","GO Biological Processes","GO:0006690","icosanoid metabolic process",-3.8026010493,{"v":0.00015754294176675,"d":"1.58E-04"},{"v":-1.5866796684,"d":"-1.587"},4,122,0.0327868852459016,"CYP2J2,HPGD,CYP4F12,CYP4F22"]
["6_Member","Reactome Gene Sets","R-HSA-556833","Metabolism of lipids",-2.9166391394,{"v":0.00121160445237862,"d":"1.21E-03"},{"v":-0.8926032848,"d":"-0.893"},7,739,0.0094722598105548,"CYP2J2,CYP4B1,FABP6,GPX2,HMGCS2,HPGD,CYP4F22"]
["6_Member","Reactome Gene Sets","R-HSA-211859","Biological oxidations",-2.8244050725,{"v":0.00149828671073712,"d":"1.50E-03"},{"v":-0.8360847701,"d":"-0.836"},4,222,0.018018018018018,"CYP2J2,CYP4B1,CYP4F12,CYP4F22"]
["6_Member","GO Biological Processes","GO:0001676","long-chain fatty acid metabolic process",-2.6910639052,{"v":0.00203674235479961,"d":"2.04E-03"},{"v":-0.735743863,"d":"-0.736"},3,113,0.0265486725663717,"CYP2J2,HPGD,CYP4F12"]
["6_Member","GO Biological Processes","GO:0033559","unsaturated fatty acid metabolic process",-2.6375622772,{"v":0.00230376259614716,"d":"2.30E-03"},{"v":-0.6961408444,"d":"-0.696"},3,118,0.0254237288135593,"CYP2J2,HPGD,CYP4F12"]
["7_Summary","Canonical Pathways","M5885","NABA MATRISOME ASSOCIATED",-7.0942389444,{"v":8.04935452059942e-8,"d":"8.05E-08"},{"v":-4.2427581617,"d":"-4.243"},12,751,0.0159786950732357,"C1QB,CTSE,CXCL8,CXCL10,MMP9,MMP11,SERPINE2,S100A8,S100A9,ANXA10,SULF1,GREM1"]
["7_Member","Canonical Pathways","M5885","NABA MATRISOME ASSOCIATED",-7.0942389444,{"v":8.04935452059942e-8,"d":"8.05E-08"},{"v":-4.2427581617,"d":"-4.243"},12,751,0.0159786950732357,"C1QB,CTSE,CXCL8,CXCL10,MMP9,MMP11,SERPINE2,S100A8,S100A9,ANXA10,SULF1,GREM1"]
["7_Member","Canonical Pathways","M3468","NABA ECM REGULATORS",-3.7311594191,{"v":0.000185712262473274,"d":"1.86E-04"},{"v":-1.5216248369,"d":"-1.522"},5,238,0.0210084033613445,"CTSE,MMP9,MMP11,SERPINE2,SULF1"]
["8_Summary","GO Biological Processes","GO:0030595","leukocyte chemotaxis",-6.0743519982,{"v":8.42651506971722e-7,"d":"8.43E-07"},{"v":-3.3615653044,"d":"-3.362"},7,233,0.0300429184549356,"FCER1G,CXCL8,CXCL10,S100A8,S100A9,GREM1,C10orf99,COL1A1,COL1A2,MMP9,VCAN,HPGD,SMAD6,MT1G,TYROBP,DHRS2,SERPINE2,APOE,C1QB"]
["8_Member","GO Biological Processes","GO:0030595","leukocyte chemotaxis",-6.0743519982,{"v":8.42651506971722e-7,"d":"8.43E-07"},{"v":-3.3615653044,"d":"-3.362"},7,233,0.0300429184549356,"FCER1G,CXCL8,CXCL10,S100A8,S100A9,GREM1,C10orf99"]
["8_Member","GO Biological Processes","GO:0050900","leukocyte migration",-5.6956736997,{"v":2.01523779829316e-6,"d":"2.02E-06"},{"v":-3.0721361073,"d":"-3.072"},9,518,0.0173745173745174,"COL1A1,COL1A2,FCER1G,CXCL8,CXCL10,S100A8,S100A9,GREM1,C10orf99"]
["8_Member","KEGG Pathway","ko04657","IL-17 signaling pathway",-5.6941153871,{"v":2.02248175690835e-6,"d":"2.02E-06"},{"v":-3.0721361073,"d":"-3.072"},5,93,0.0537634408602151,"CXCL8,CXCL10,MMP9,S100A8,S100A9"]
["8_Member","KEGG Pathway","hsa04657","IL-17 signaling pathway",-5.6483692985,{"v":2.24714295488923e-6,"d":"2.25E-06"},{"v":-3.0494755868,"d":"-3.049"},5,95,0.0526315789473684,"CXCL8,CXCL10,MMP9,S100A8,S100A9"]
["8_Member","GO Biological Processes","GO:0030593","neutrophil chemotaxis",-5.4750297857,{"v":3.34942466639486e-6,"d":"3.35E-06"},{"v":-2.8922026299,"d":"-2.892"},5,103,0.0485436893203883,"FCER1G,CXCL8,CXCL10,S100A8,S100A9"]
["8_Member","GO Biological Processes","GO:0060326","cell chemotaxis",-5.235779151,{"$f":"10^(E195)","v":{"v":5.81059825046977e-6,"d":"5.81E-06"}},{"v":-2.6957039757,"d":"-2.696"},7,312,{"$f":"H195/I195","v":0.0224358974358974},"FCER1G,CXCL8,CXCL10,S100A8,S100A9,GREM1,C10orf99"]
["8_Member","GO Biological Processes","GO:1990266","neutrophil migration",-5.0973681024,{"v":7.99156613032064e-6,"d":"7.99E-06"},{"v":-2.6023713017,"d":"-2.602"},5,123,0.040650406504065,"FCER1G,CXCL8,CXCL10,S100A8,S100A9"]
["8_Member","GO Biological Processes","GO:0071621","granulocyte chemotaxis",-5.0296793936,{"v":9.3394350543175e-6,"d":"9.34E-06"},{"v":-2.5467471044,"d":"-2.547"},5,127,0.0393700787401575,"FCER1G,CXCL8,CXCL10,S100A8,S100A9"]
["8_Member","GO Biological Processes","GO:0097529","myeloid leukocyte migration",-4.9837078905,{"v":1.0382264994143e-5,"d":"1.04E-05"},{"v":-2.5066844608,"d":"-2.507"},6,224,0.0267857142857143,"FCER1G,CXCL8,CXCL10,S100A8,S100A9,GREM1"]
["8_Member","Canonical Pathways","M264","PID TOLL ENDOGENOUS PATHWAY",-4.6934830753,{"v":2.02542853737522e-5,"d":"2.03E-05"},{"v":-2.271507212,"d":"-2.272"},3,24,0.125,"VCAN,S100A8,S100A9"]
["8_Member","GO Biological Processes","GO:0097530","granulocyte migration",-4.6659148414,{"v":2.15816755178336e-5,"d":"2.16E-05"},{"v":-2.2541581433,"d":"-2.254"},5,151,0.033112582781457,"FCER1G,CXCL8,CXCL10,S100A8,S100A9"]
["8_Member","GO Biological Processes","GO:0032496","response to lipopolysaccharide",-4.0148561896,{"v":9.66370825877682e-5,"d":"9.66E-05"},{"v":-1.713924019,"d":"-1.714"},6,334,0.0179640718562874,"HPGD,CXCL8,CXCL10,SMAD6,S100A8,S100A9"]
["8_Member","GO Biological Processes","GO:0050832","defense response to fungus",-3.983590804,{"v":0.000103850644470548,"d":"1.04E-04"},{"v":-1.6948320661,"d":"-1.695"},3,41,0.0731707317073171,"S100A8,S100A9,C10orf99"]
["8_Member","GO Biological Processes","GO:0002274","myeloid leukocyte activation",-3.9785473923,{"v":0.000105063679807557,"d":"1.05E-04"},{"v":-1.6948320661,"d":"-1.695"},8,664,0.0120481927710843,"FCER1G,CXCL8,MMP9,MT1G,S100A8,S100A9,TYROBP,DHRS2"]
["8_Member","GO Biological Processes","GO:0002237","response to molecule of bacterial origin",-3.8637764486,{"v":0.000136843303993387,"d":"1.37E-04"},{"v":-1.6314646515,"d":"-1.631"},6,356,0.0168539325842697,"HPGD,CXCL8,CXCL10,SMAD6,S100A8,S100A9"]
["8_Member","GO Biological Processes","GO:0009620","response to fungus",-3.6257279273,{"v":0.000236740234085159,"d":"2.37E-04"},{"v":-1.4485842741,"d":"-1.449"},3,54,0.0555555555555556,"S100A8,S100A9,C10orf99"]
["8_Member","GO Biological Processes","GO:0009617","response to bacterium",-3.6021768188,{"v":0.000249932757745772,"d":"2.50E-04"},{"v":-1.4347747391,"d":"-1.435"},8,754,0.0106100795755968,"FCER1G,HPGD,CXCL8,CXCL10,SMAD6,S100A8,S100A9,C10orf99"]
["8_Member","GO Biological Processes","GO:0019730","antimicrobial humoral response",-3.5974706549,{"v":0.000252655842288061,"d":"2.53E-04"},{"v":-1.4330590935,"d":"-1.433"},4,138,0.0289855072463768,"CXCL8,CXCL10,S100A8,S100A9"]
["8_Member","GO Biological Processes","GO:0006935","chemotaxis",-3.2183476214,{"v":0.000604856536921415,"d":"6.05E-04"},{"v":-1.1126417204,"d":"-1.113"},7,656,0.0106707317073171,"FCER1G,CXCL8,CXCL10,S100A8,S100A9,GREM1,C10orf99"]
["8_Member","GO Biological Processes","GO:0042330","taxis",-3.2105460692,{"v":0.000615820200519294,"d":"6.16E-04"},{"v":-1.1073289685,"d":"-1.107"},7,658,0.0106382978723404,"FCER1G,CXCL8,CXCL10,S100A8,S100A9,GREM1,C10orf99"]
["8_Member","GO Biological Processes","GO:0061844","antimicrobial humoral immune response mediated by antimicrobial peptide",-3.2051450739,{"v":0.000623526514775781,"d":"6.24E-04"},{"v":-1.1068631909,"d":"-1.107"},3,75,0.04,"CXCL8,CXCL10,S100A9"]
["8_Member","GO Biological Processes","GO:0048708","astrocyte differentiation",-3.0768480242,{"v":0.00083782241607473,"d":"8.38E-04"},{"v":-1.0047507241,"d":"-1.005"},3,83,0.036144578313253,"SERPINE2,S100A8,S100A9"]
["8_Member","GO Biological Processes","GO:0042119","neutrophil activation",-3.0668826126,{"v":0.000857269529136841,"d":"8.57E-04"},{"v":-0.9979657453,"d":"-0.998"},6,503,0.0119284294234592,"FCER1G,CXCL8,MMP9,S100A8,S100A9,TYROBP"]
["8_Member","GO Biological Processes","GO:0036230","granulocyte activation",-3.0402833759,{"v":0.000911415949010262,"d":"9.11E-04"},{"v":-0.9818299565,"d":"-0.982"},6,509,0.0117878192534381,"FCER1G,CXCL8,MMP9,S100A8,S100A9,TYROBP"]
["8_Member","GO Biological Processes","GO:0032103","positive regulation of response to external stimulus",-3.0316048962,{"v":0.000929811907903892,"d":"9.30E-04"},{"v":-0.9753843582,"d":"-0.975"},5,339,0.0147492625368732,"FCER1G,CXCL8,CXCL10,S100A8,S100A9"]
["8_Member","GO Biological Processes","GO:0050727","regulation of inflammatory response",-2.9084907124,{"v":0.00123455171638092,"d":"1.23E-03"},{"v":-0.888571424,"d":"-0.889"},6,540,0.0111111111111111,"APOE,C1QB,FCER1G,MMP9,S100A8,S100A9"]
["8_Member","GO Biological Processes","GO:0006959","humoral immune response",-2.8173193927,{"v":0.00152293233344824,"d":"1.52E-03"},{"v":-0.8308997257,"d":"-0.831"},5,379,0.0131926121372032,"C1QB,CXCL8,CXCL10,S100A8,S100A9"]
["8_Member","Reactome Gene Sets","R-HSA-6798695","Neutrophil degranulation",-2.3756566471,{"v":0.00421059386071027,"d":"4.21E-03"},{"v":-0.4687341915,"d":"-0.469"},5,480,0.0104166666666667,"FCER1G,MMP9,S100A8,S100A9,TYROBP"]
["8_Member","GO Biological Processes","GO:0043312","neutrophil degranulation",-2.3454487841,{"v":0.00451389254071127,"d":"4.51E-03"},{"v":-0.4405302334,"d":"-0.441"},5,488,0.0102459016393443,"FCER1G,MMP9,S100A8,S100A9,TYROBP"]
["8_Member","GO Biological Processes","GO:0002283","neutrophil activation involved in immune response",-2.3342732239,{"v":0.00463155447112736,"d":"4.63E-03"},{"v":-0.4320628705,"d":"-0.432"},5,491,0.010183299389002,"FCER1G,MMP9,S100A8,S100A9,TYROBP"]
["8_Member","GO Biological Processes","GO:0002446","neutrophil mediated immunity",-2.2939862275,{"v":0.00508175557747805,"d":"5.08E-03"},{"v":-0.3979801865,"d":"-0.398"},5,502,0.0099601593625498,"FCER1G,MMP9,S100A8,S100A9,TYROBP"]
["8_Member","GO Biological Processes","GO:0050729","positive regulation of inflammatory response",-2.2815934501,{"v":0.00522885441256432,"d":"5.23E-03"},{"v":-0.3901831608,"d":"-0.390"},3,158,0.0189873417721519,"FCER1G,S100A8,S100A9"]
["8_Member","GO Biological Processes","GO:0051092","positive regulation of NF-kappaB transcription factor activity",-2.2664574936,{"v":0.00541430237559024,"d":"5.41E-03"},{"v":-0.3765683774,"d":"-0.377"},3,160,0.01875,"S100A8,S100A9,GREM1"]
["8_Member","GO Biological Processes","GO:0051235","maintenance of location",-2.2365329415,{"v":0.00580052173544688,"d":"5.80E-03"},{"v":-0.35267579,"d":"-0.353"},4,324,0.0123456790123457,"APOE,CXCL10,S100A8,S100A9"]
["8_Member","GO Biological Processes","GO:2001242","regulation of intrinsic apoptotic signaling pathway",-2.2222651025,{"v":0.005994250628707,"d":"5.99E-03"},{"v":-0.3458319692,"d":"-0.346"},3,166,0.0180722891566265,"MMP9,S100A8,S100A9"]
["8_Member","GO Biological Processes","GO:0043299","leukocyte degranulation",-2.1659170042,{"v":0.00682469104864692,"d":"6.82E-03"},{"v":-0.3011044834,"d":"-0.301"},5,539,0.00927643784786642,"FCER1G,MMP9,S100A8,S100A9,TYROBP"]
["8_Member","Canonical Pathways","M5883","NABA SECRETED FACTORS",-2.1505747026,{"v":0.00707009578145112,"d":"7.07E-03"},{"v":-0.2871931369,"d":"-0.287"},4,343,0.0116618075801749,"CXCL8,CXCL10,S100A8,S100A9"]
["8_Member","GO Biological Processes","GO:0002275","myeloid cell activation involved in immune response",-2.1266612387,{"v":0.00747031235530662,"d":"7.47E-03"},{"v":-0.2685437844,"d":"-0.269"},5,551,0.00907441016333938,"FCER1G,MMP9,S100A8,S100A9,TYROBP"]
["8_Member","GO Biological Processes","GO:0042742","defense response to bacterium",-2.1117688168,{"v":0.00773092007138575,"d":"7.73E-03"},{"v":-0.2624433155,"d":"-0.262"},4,352,0.0113636363636364,"FCER1G,S100A8,S100A9,C10orf99"]
["8_Member","GO Biological Processes","GO:0002444","myeloid leukocyte mediated immunity",-2.1074240534,{"v":0.00780864980798153,"d":"7.81E-03"},{"v":-0.2594794578,"d":"-0.259"},5,557,0.00897666068222621,"FCER1G,MMP9,S100A8,S100A9,TYROBP"]
["8_Member","GO Biological Processes","GO:2001235","positive regulation of apoptotic signaling pathway",-2.1060181054,{"v":0.00783396982873022,"d":"7.83E-03"},{"v":-0.2594500386,"d":"-0.259"},3,183,0.0163934426229508,"MMP9,S100A8,S100A9"]
["9_Summary","GO Biological Processes","GO:0002573","myeloid leukocyte differentiation",-5.1316455578,{"v":7.38506704178876e-6,"d":"7.39E-06"},{"v":-2.6304884485,"d":"-2.630"},6,211,0.028436018957346,"FCER1G,MMP9,MT1G,TYROBP,DHRS2,TESC,COL3A1"]
["9_Member","GO Biological Processes","GO:0002573","myeloid leukocyte differentiation",-5.1316455578,{"v":7.38506704178876e-6,"d":"7.39E-06"},{"v":-2.6304884485,"d":"-2.630"},6,211,0.028436018957346,"FCER1G,MMP9,MT1G,TYROBP,DHRS2,TESC"]
["9_Member","GO Biological Processes","GO:0030099","myeloid cell differentiation",-3.4074927127,{"v":0.000391297692901628,"d":"3.91E-04"},{"v":-1.2743206579,"d":"-1.274"},6,433,0.0138568129330254,"FCER1G,MMP9,MT1G,TYROBP,DHRS2,TESC"]
["9_Member","GO Biological Processes","GO:0002521","leukocyte differentiation",-2.9126013325,{"v":0.00122292174545855,"d":"1.22E-03"},{"v":-0.8906286385,"d":"-0.891"},6,539,0.0111317254174397,"FCER1G,MMP9,MT1G,TYROBP,DHRS2,TESC"]
["9_Member","GO Biological Processes","GO:0007229","integrin-mediated signaling pathway",-2.7243968588,{"v":0.00188626688844433,"d":"1.89E-03"},{"v":-0.7619570755,"d":"-0.762"},3,110,0.0272727272727273,"COL3A1,FCER1G,TYROBP"]
["10_Summary","GO Biological Processes","GO:0008285","negative regulation of cell proliferation",-5.0732655752,{"v":8.44762107130418e-6,"d":"8.45E-06"},{"v":-2.5843429223,"d":"-2.584"},10,788,0.0126903553299492,"APOE,FABP6,CXCL8,SMAD6,SERPINE2,TYROBP,DHRS2,SULF1,GREM1,TESC,SPINK1,PSCA"]
["10_Member","GO Biological Processes","GO:0008285","negative regulation of cell proliferation",-5.0732655752,{"v":8.44762107130418e-6,"d":"8.45E-06"},{"v":-2.5843429223,"d":"-2.584"},10,788,0.0126903553299492,"APOE,FABP6,CXCL8,SMAD6,SERPINE2,TYROBP,DHRS2,SULF1,GREM1,TESC"]
["10_Member","GO Biological Processes","GO:0001933","negative regulation of protein phosphorylation",-3.3499177863,{"v":0.000446768159163772,"d":"4.47E-04"},{"v":-1.2278153366,"d":"-1.228"},6,444,0.0135135135135135,"APOE,SMAD6,SPINK1,PSCA,GREM1,TESC"]
["10_Member","GO Biological Processes","GO:0042326","negative regulation of phosphorylation",-3.1536260537,{"v":0.000702059541820413,"d":"7.02E-04"},{"v":-1.0639234428,"d":"-1.064"},6,484,0.012396694214876,"APOE,SMAD6,SPINK1,PSCA,GREM1,TESC"]
["10_Member","GO Biological Processes","GO:0045936","negative regulation of phosphate metabolic process",-2.6628033731,{"v":0.00217368509240598,"d":"2.17E-03"},{"v":-0.7127475709,"d":"-0.713"},6,604,0.00993377483443709,"APOE,SMAD6,SPINK1,PSCA,GREM1,TESC"]
["10_Member","GO Biological Processes","GO:0010563","negative regulation of phosphorus metabolic process",-2.659215999,{"v":0.0021917146016536,"d":"2.19E-03"},{"v":-0.7120842831,"d":"-0.712"},6,605,0.00991735537190083,"APOE,SMAD6,SPINK1,PSCA,GREM1,TESC"]
["10_Member","GO Biological Processes","GO:0031400","negative regulation of protein modification process",-2.5346664909,{"v":0.0029196682631742,"d":"2.92E-03"},{"v":-0.6050518489,"d":"-0.605"},6,641,0.0093603744149766,"APOE,SMAD6,SPINK1,PSCA,GREM1,TESC"]
["11_Summary","Canonical Pathways","M167","PID AP1 PATHWAY",-4.7466160675,{"v":1.79218951621755e-5,"d":"1.79E-05"},{"v":-2.308845937,"d":"-2.309"},4,70,0.0571428571428571,"COL1A2,CXCL8,MMP9,MT2A,VCAN,HPGD,SERPINE2,SPP1"]
["11_Member","Canonical Pathways","M167","PID AP1 PATHWAY",-4.7466160675,{"v":1.79218951621755e-5,"d":"1.79E-05"},{"v":-2.308845937,"d":"-2.309"},4,70,0.0571428571428571,"COL1A2,CXCL8,MMP9,MT2A"]
["11_Member","Canonical Pathways","M65","PID FRA PATHWAY",-4.1181861759,{"v":7.61752387549916e-5,"d":"7.62E-05"},{"v":-1.7805311983,"d":"-1.781"},3,37,0.0810810810810811,"COL1A2,CXCL8,MMP9"]
["11_Member","Canonical Pathways","M223","PID BETA CATENIN NUC PATHWAY",-3.1233646972,{"v":0.000752723201708241,"d":"7.53E-04"},{"v":-1.0419273709,"d":"-1.042"},3,80,0.0375,"VCAN,CXCL8,MMP9"]
["11_Member","GO Biological Processes","GO:0044706","multi-multicellular organism process",-2.7960281099,{"v":0.00159945449987324,"d":"1.60E-03"},{"v":-0.8189888179,"d":"-0.819"},4,226,0.0176991150442478,"HPGD,MMP9,SERPINE2,SPP1"]
["11_Member","Reactome Gene Sets","R-HSA-6785807","Interleukin-4 and Interleukin-13 signaling",-2.7471637471,{"v":0.00178993084834337,"d":"1.79E-03"},{"v":-0.7793064987,"d":"-0.779"},3,108,0.0277777777777778,"COL1A2,CXCL8,MMP9"]
["11_Member","KEGG Pathway","ko05202","Transcriptional misregulation in cancer",-2.1256422402,{"v":0.00748786075806977,"d":"7.49E-03"},{"v":-0.2685437844,"d":"-0.269"},3,180,0.0166666666666667,"HPGD,CXCL8,MMP9"]
["11_Member","GO Biological Processes","GO:0007565","female pregnancy",-2.0249232121,{"v":0.00944227811083119,"d":"9.44E-03"},{"v":-0.1984960565,"d":"-0.198"},3,196,0.0153061224489796,"HPGD,MMP9,SPP1"]
["12_Summary","GO Biological Processes","GO:0045992","negative regulation of embryonic development",-4.6386517327,{"v":2.29799070285691e-5,"d":"2.30E-05"},{"v":-2.2319158359,"d":"-2.232"},3,25,0.12,"COL5A1,COL5A2,SULF1,OSR1,MMP9,GREM1,CTHRC1,C1QB"]
["12_Member","GO Biological Processes","GO:0045992","negative regulation of embryonic development",-4.6386517327,{"v":2.29799070285691e-5,"d":"2.30E-05"},{"v":-2.2319158359,"d":"-2.232"},3,25,0.12,"COL5A1,COL5A2,SULF1"]
["12_Member","GO Biological Processes","GO:0010470","regulation of gastrulation",-3.9213677382,{"v":0.000119848405880572,"d":"1.20E-04"},{"v":-1.6720226018,"d":"-1.672"},3,43,0.0697674418604651,"COL5A1,COL5A2,OSR1"]
["12_Member","GO Biological Processes","GO:0035987","endodermal cell differentiation",-3.8335010342,{"v":0.000146723259293346,"d":"1.47E-04"},{"v":-1.6110975258,"d":"-1.611"},3,46,0.0652173913043478,"COL5A1,COL5A2,MMP9"]
["12_Member","GO Biological Processes","GO:0045995","regulation of embryonic development",-3.6462749444,{"v":0.000225800581281206,"d":"2.26E-04"},{"v":-1.4613877972,"d":"-1.461"},4,134,0.0298507462686567,"COL5A1,COL5A2,SULF1,OSR1"]
["12_Member","GO Biological Processes","GO:0001706","endoderm formation",-3.6020529412,{"v":0.000250004058412828,"d":"2.50E-04"},{"v":-1.4347747391,"d":"-1.435"},3,55,0.0545454545454545,"COL5A1,COL5A2,MMP9"]
["12_Member","GO Biological Processes","GO:0048598","embryonic morphogenesis",-3.4403759093,{"v":0.000362763923754866,"d":"3.63E-04"},{"v":-1.300946636,"d":"-1.301"},7,602,0.0116279069767442,"COL5A1,COL5A2,MMP9,SULF1,GREM1,CTHRC1,OSR1"]
["12_Member","GO Biological Processes","GO:0007492","endoderm development",-3.1392809779,{"v":0.000725636336585842,"d":"7.26E-04"},{"v":-1.0540164318,"d":"-1.054"},3,79,0.0379746835443038,"COL5A1,COL5A2,MMP9"]
["12_Member","GO Biological Processes","GO:0007369","gastrulation",-3.082470018,{"$f":"10^(E259)","v":{"v":0.000827046602674274,"d":"8.27E-04"}},{"v":-1.0057278128,"d":"-1.006"},4,189,{"$f":"H259/I259","v":0.0211640211640212},"COL5A1,COL5A2,MMP9,OSR1"]
["12_Member","GO Biological Processes","GO:0001704","formation of primary germ layer",-2.547128879,{"v":0.00283707698711177,"d":"2.84E-03"},{"v":-0.6158470776,"d":"-0.616"},3,127,0.0236220472440945,"COL5A1,COL5A2,MMP9"]
["12_Member","GO Biological Processes","GO:0090596","sensory organ morphogenesis",-2.5222467416,{"v":0.00300436890489568,"d":"3.00E-03"},{"v":-0.5942928835,"d":"-0.594"},4,269,0.0148698884758364,"COL5A1,COL5A2,CTHRC1,OSR1"]
["12_Member","GO Biological Processes","GO:0007423","sensory organ development",-2.0420509045,{"v":0.00907714129005936,"d":"9.08E-03"},{"v":-0.2111595297,"d":"-0.211"},5,578,0.00865051903114187,"C1QB,COL5A1,COL5A2,CTHRC1,OSR1"]
["13_Summary","GO Biological Processes","GO:0048514","blood vessel morphogenesis",-4.6128809216,{"v":2.43847932884865e-5,"d":"2.44E-05"},{"v":-2.2111084444,"d":"-2.211"},9,707,0.0127298444130127,"APOE,COL3A1,HPGD,ID1,CXCL8,CXCL10,THBS2,SULF1,GREM1,C10orf99,SPP1,COL1A1,TESC,OSR1"]
["13_Member","GO Biological Processes","GO:0048514","blood vessel morphogenesis",-4.6128809216,{"v":2.43847932884865e-5,"d":"2.44E-05"},{"v":-2.2111084444,"d":"-2.211"},9,707,0.0127298444130127,"APOE,COL3A1,HPGD,ID1,CXCL8,CXCL10,THBS2,SULF1,GREM1"]
["13_Member","GO Biological Processes","GO:0045765","regulation of angiogenesis",-3.5676735848,{"v":0.000270599141982468,"d":"2.71E-04"},{"v":-1.4089391563,"d":"-1.409"},6,404,0.0148514851485149,"ID1,CXCL8,CXCL10,THBS2,SULF1,GREM1"]
["13_Member","GO Biological Processes","GO:1901342","regulation of vasculature development",-3.3396257055,{"v":0.000457482298562447,"d":"4.57E-04"},{"v":-1.2212572608,"d":"-1.221"},6,446,0.0134529147982063,"ID1,CXCL8,CXCL10,THBS2,SULF1,GREM1"]
["13_Member","GO Biological Processes","GO:0002685","regulation of leukocyte migration",-2.89037455,{"v":0.00128713900140644,"d":"1.29E-03"},{"v":-0.874533174,"d":"-0.875"},4,213,0.0187793427230047,"CXCL8,CXCL10,GREM1,C10orf99"]
["13_Member","KEGG Pathway","ko04620","Toll-like receptor signaling pathway",-2.7940804272,{"v":0.00160664369035783,"d":"1.61E-03"},{"v":-0.8188931401,"d":"-0.819"},3,104,0.0288461538461538,"CXCL8,CXCL10,SPP1"]
["13_Member","GO Biological Processes","GO:0071396","cellular response to lipid",-2.7137927688,{"v":0.00193289040943335,"d":"1.93E-03"},{"v":-0.7560898115,"d":"-0.756"},6,590,0.0101694915254237,"COL1A1,CXCL8,CXCL10,SPP1,TESC,OSR1"]
["13_Member","KEGG Pathway","hsa04620","Toll-like receptor signaling pathway",-2.7131788765,{"v":0.00193562455786764,"d":"1.94E-03"},{"v":-0.7560898115,"d":"-0.756"},3,111,0.027027027027027,"CXCL8,CXCL10,SPP1"]
["13_Member","GO Biological Processes","GO:0001525","angiogenesis",-2.6378414356,{"v":0.00230228224569639,"d":"2.30E-03"},{"v":-0.6961408444,"d":"-0.696"},6,611,0.00981996726677578,"ID1,CXCL8,CXCL10,THBS2,SULF1,GREM1"]
["13_Member","GO Biological Processes","GO:0002688","regulation of leukocyte chemotaxis",-2.5764853707,{"v":0.00265164041256393,"d":"2.65E-03"},{"v":-0.6401633447,"d":"-0.640"},3,124,0.0241935483870968,"CXCL8,CXCL10,GREM1"]
["13_Member","GO Biological Processes","GO:0016525","negative regulation of angiogenesis",-2.0492218944,{"v":0.00892849183082477,"d":"8.93E-03"},{"v":-0.2161843451,"d":"-0.216"},3,192,0.015625,"CXCL10,THBS2,SULF1"]
["13_Member","GO Biological Processes","GO:2000181","negative regulation of blood vessel morphogenesis",-2.0370027097,{"v":0.00918326866735271,"d":"9.18E-03"},{"v":-0.2079434583,"d":"-0.208"},3,194,0.0154639175257732,"CXCL10,THBS2,SULF1"]
["14_Summary","GO Biological Processes","GO:0060291","long-term synaptic potentiation",-4.3736433332,{"v":4.23015875831784e-5,"d":"4.23E-05"},{"v":-1.9958711324,"d":"-1.996"},4,87,0.0459770114942529,"APOE,SERPINE2,TYROBP,NSG1,FCER1G,SPP1,GPX2,S100A9,THBS2,MMD"]
["14_Member","GO Biological Processes","GO:0060291","long-term synaptic potentiation",-4.3736433332,{"v":4.23015875831784e-5,"d":"4.23E-05"},{"v":-1.9958711324,"d":"-1.996"},4,87,0.0459770114942529,"APOE,SERPINE2,TYROBP,NSG1"]
["14_Member","GO Biological Processes","GO:0010543","regulation of platelet activation",-4.1542236441,{"v":7.01094170291738e-5,"d":"7.01E-05"},{"v":-1.8121364186,"d":"-1.812"},3,36,0.0833333333333333,"APOE,FCER1G,SERPINE2"]
["14_Member","GO Biological Processes","GO:1900271","regulation of long-term synaptic potentiation",-3.7781966673,{"v":0.000166649238192223,"d":"1.67E-04"},{"v":-1.5654804263,"d":"-1.565"},3,48,0.0625,"APOE,TYROBP,NSG1"]
["14_Member","GO Biological Processes","GO:0050806","positive regulation of synaptic transmission",-3.2354263345,{"v":0.000581532064041218,"d":"5.82E-04"},{"v":-1.1246996321,"d":"-1.125"},4,172,0.0232558139534884,"APOE,SERPINE2,TYROBP,NSG1"]
["14_Member","GO Biological Processes","GO:0030193","regulation of blood coagulation",-3.0921533153,{"v":0.000808810321321274,"d":"8.09E-04"},{"v":-1.0130698944,"d":"-1.013"},3,82,0.0365853658536585,"APOE,FCER1G,SERPINE2"]
["14_Member","GO Biological Processes","GO:1900046","regulation of hemostasis",-3.0768480242,{"v":0.00083782241607473,"d":"8.38E-04"},{"v":-1.0047507241,"d":"-1.005"},3,83,0.036144578313253,"APOE,FCER1G,SERPINE2"]
["14_Member","GO Biological Processes","GO:0048167","regulation of synaptic plasticity",-3.0654672937,{"v":0.000860067835332006,"d":"8.60E-04"},{"v":-0.9979657453,"d":"-0.998"},4,191,0.0209424083769634,"APOE,SERPINE2,TYROBP,NSG1"]
["14_Member","GO Biological Processes","GO:1903034","regulation of response to wounding",-3.0156035617,{"v":0.000964709240170062,"d":"9.65E-04"},{"v":-0.9693310756,"d":"-0.969"},4,197,0.0203045685279188,"APOE,FCER1G,SERPINE2,SPP1"]
["14_Member","GO Biological Processes","GO:0050818","regulation of coagulation",-3.0031378466,{"v":0.000992800879905605,"d":"9.93E-04"},{"v":-0.9665128646,"d":"-0.967"},3,88,0.0340909090909091,"APOE,FCER1G,SERPINE2"]
["14_Member","GO Biological Processes","GO:1903035","negative regulation of response to wounding",-2.8939737983,{"v":0.00127651582078604,"d":"1.28E-03"},{"v":-0.8760982523,"d":"-0.876"},3,96,0.03125,"APOE,SERPINE2,SPP1"]
["14_Member","GO Biological Processes","GO:0098869","cellular oxidant detoxification",-2.8061107558,{"v":0.00156274905228152,"d":"1.56E-03"},{"v":-0.8253435913,"d":"-0.825"},3,103,0.029126213592233,"APOE,GPX2,S100A9"]
["14_Member","GO Biological Processes","GO:1990748","cellular detoxification",-2.6801631034,{"v":0.00208851162325651,"d":"2.09E-03"},{"v":-0.7283596349,"d":"-0.728"},3,114,0.0263157894736842,"APOE,GPX2,S100A9"]
["14_Member","GO Biological Processes","GO:0051668","localization within membrane",-2.2892403014,{"v":0.00513759302491224,"d":"5.14E-03"},{"v":-0.3947715876,"d":"-0.395"},3,157,0.0191082802547771,"APOE,TYROBP,NSG1"]
["14_Member","GO Biological Processes","GO:0061041","regulation of wound healing",-2.2295075168,{"v":0.00589511773665187,"d":"5.90E-03"},{"v":-0.3486352188,"d":"-0.349"},3,165,0.0181818181818182,"APOE,FCER1G,SERPINE2"]
["14_Member","GO Biological Processes","GO:0051962","positive regulation of nervous system development",-2.1234372399,{"v":0.00752597480531768,"d":"7.53E-03"},{"v":-0.2685437844,"d":"-0.269"},5,552,0.00905797101449275,"APOE,SERPINE2,S100A9,THBS2,MMD"]
["14_Member","GO Biological Processes","GO:0010720","positive regulation of cell development",-2.0666040737,{"v":0.00857819523462861,"d":"8.58E-03"},{"v":-0.2268539568,"d":"-0.227"},5,570,0.0087719298245614,"APOE,SERPINE2,S100A9,TYROBP,MMD"]
["15_Summary","GO Biological Processes","GO:0033273","response to vitamin",-4.2970748851,{"v":5.0457428666354e-5,"d":"5.05E-05"},{"v":-1.93759147,"d":"-1.938"},4,91,0.043956043956044,"COL1A1,CXCL10,SPP1,POSTN,COL3A1,SERPINE2,CXCL8,SULF1,APOE,GREM1,TESC,MMP9"]
["15_Member","GO Biological Processes","GO:0033273","response to vitamin",-4.2970748851,{"v":5.0457428666354e-5,"d":"5.05E-05"},{"v":-1.93759147,"d":"-1.938"},4,91,0.043956043956044,"COL1A1,CXCL10,SPP1,POSTN"]
["15_Member","GO Biological Processes","GO:0009612","response to mechanical stimulus",-3.9945826663,{"v":0.000101255199505563,"d":"1.01E-04"},{"v":-1.7014059604,"d":"-1.701"},5,209,0.0239234449760766,"COL1A1,COL3A1,CXCL10,SERPINE2,POSTN"]
["15_Member","GO Biological Processes","GO:0044344","cellular response to fibroblast growth factor stimulus",-3.5042548232,{"v":0.000313144780158695,"d":"3.13E-04"},{"v":-1.3566567608,"d":"-1.357"},4,146,0.0273972602739726,"COL1A1,CXCL8,POSTN,SULF1"]
["15_Member","GO Biological Processes","GO:0071774","response to fibroblast growth factor",-3.4270841327,{"v":0.000374038121577924,"d":"3.74E-04"},{"v":-1.2903439979,"d":"-1.290"},4,153,0.0261437908496732,"COL1A1,CXCL8,POSTN,SULF1"]
["15_Member","GO Biological Processes","GO:0007584","response to nutrient",-2.8460615428,{"v":0.001425405588579,"d":"1.43E-03"},{"v":-0.8481112565,"d":"-0.848"},4,219,0.0182648401826484,"COL1A1,CXCL10,SPP1,POSTN"]
["15_Member","GO Biological Processes","GO:0031667","response to nutrient levels",-2.2477226345,{"v":0.00565297891380652,"d":"5.65E-03"},{"v":-0.3608599729,"d":"-0.361"},5,515,0.00970873786407767,"APOE,COL1A1,CXCL10,SPP1,POSTN"]
["15_Member","GO Biological Processes","GO:0030155","regulation of cell adhesion",-2.2379283876,{"v":0.00578191379629592,"d":"5.78E-03"},{"v":-0.35267579,"d":"-0.353"},6,738,0.00813008130081301,"COL1A1,CXCL8,SERPINE2,POSTN,GREM1,TESC"]
["15_Member","GO Biological Processes","GO:0009991","response to extracellular stimulus",-2.1363764286,{"v":0.00730505636750594,"d":"7.31E-03"},{"v":-0.2758427057,"d":"-0.276"},5,548,0.00912408759124088,"APOE,COL1A1,CXCL10,SPP1,POSTN"]
["15_Member","GO Biological Processes","GO:0030335","positive regulation of cell migration",-2.0759215326,{"v":0.00839611672060654,"d":"8.40E-03"},{"v":-0.2334570663,"d":"-0.233"},5,567,0.00881834215167548,"COL1A1,CXCL8,CXCL10,MMP9,POSTN"]
["16_Summary","GO Biological Processes","GO:0060840","artery development",-4.1035707975,{"v":7.87823992067749e-5,"d":"7.88E-05"},{"v":-1.7701528729,"d":"-1.770"},4,102,0.0392156862745098,"APOE,COL3A1,HPGD,SMAD6,ID1,SPP1,POSTN,FABP6,CYP4F12,VCAN,HMGCS2,DHRS2,CXCL10"]
["16_Member","GO Biological Processes","GO:0060840","artery development",-4.1035707975,{"v":7.87823992067749e-5,"d":"7.88E-05"},{"v":-1.7701528729,"d":"-1.770"},4,102,0.0392156862745098,"APOE,COL3A1,HPGD,SMAD6"]
["16_Member","GO Biological Processes","GO:0048844","artery morphogenesis",-3.2051450739,{"v":0.000623526514775781,"d":"6.24E-04"},{"v":-1.1068631909,"d":"-1.107"},3,75,0.04,"APOE,COL3A1,HPGD"]
["16_Member","GO Biological Processes","GO:0010721","negative regulation of cell development",-3.008911021,{"v":0.000979690685559837,"d":"9.80E-04"},{"v":-0.9680072411,"d":"-0.968"},5,343,0.0145772594752187,"APOE,COL3A1,ID1,SPP1,POSTN"]
["16_Member","GO Biological Processes","GO:0016042","lipid catabolic process",-3.008911021,{"v":0.000979690685559837,"d":"9.80E-04"},{"v":-0.9680072411,"d":"-0.968"},5,343,0.0145772594752187,"APOE,FABP6,HPGD,SPP1,CYP4F12"]
["16_Member","GO Biological Processes","GO:0010771","negative regulation of cell morphogenesis involved in differentiation",-2.8681914531,{"v":0.00135459212630537,"d":"1.35E-03"},{"v":-0.8623804186,"d":"-0.862"},3,98,0.0306122448979592,"ID1,SPP1,POSTN"]
["16_Member","Reactome Gene Sets","R-HSA-8957275","Post-translational protein phosphorylation",-2.7471637471,{"v":0.00178993084834337,"d":"1.79E-03"},{"v":-0.7793064987,"d":"-0.779"},3,108,0.0277777777777778,"APOE,VCAN,SPP1"]
["16_Member","Reactome Gene Sets","R-HSA-381426","Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)",-2.5666156323,{"v":0.00271259131984632,"d":"2.71E-03"},{"v":-0.633660247,"d":"-0.634"},3,125,0.024,"APOE,VCAN,SPP1"]
["16_Member","GO Biological Processes","GO:0050768","negative regulation of neurogenesis",-2.3796109728,{"v":0.00417242969118826,"d":"4.17E-03"},{"v":-0.4711063863,"d":"-0.471"},4,295,0.0135593220338983,"APOE,COL3A1,ID1,SPP1"]
["16_Member","GO Biological Processes","GO:0010977","negative regulation of neuron projection development",-2.3125045485,{"v":0.0048696242503155,"d":"4.87E-03"},{"v":-0.4134074304,"d":"-0.413"},3,154,0.0194805194805195,"APOE,ID1,SPP1"]
["16_Member","GO Biological Processes","GO:0010769","regulation of cell morphogenesis involved in differentiation",-2.3036859751,{"v":0.00496951521837909,"d":"4.97E-03"},{"v":-0.4061371456,"d":"-0.406"},4,310,0.0129032258064516,"APOE,ID1,SPP1,POSTN"]
["16_Member","GO Biological Processes","GO:0051961","negative regulation of nervous system development",-2.2648956027,{"v":0.00543380935695999,"d":"5.43E-03"},{"v":-0.3765223501,"d":"-0.377"},4,318,0.0125786163522013,"APOE,COL3A1,ID1,SPP1"]
["16_Member","GO Biological Processes","GO:0008202","steroid metabolic process",-2.1996457555,{"v":0.00631472212526008,"d":"6.31E-03"},{"v":-0.3261470554,"d":"-0.326"},4,332,0.0120481927710843,"APOE,HMGCS2,SPP1,DHRS2"]
["16_Member","GO Biological Processes","GO:0051129","negative regulation of cellular component organization",-2.1373860363,{"v":0.00728809397110465,"d":"7.29E-03"},{"v":-0.2758427057,"d":"-0.276"},6,775,0.00774193548387097,"APOE,ID1,CXCL10,SMAD6,SPP1,POSTN"]
["16_Member","GO Biological Processes","GO:0031345","negative regulation of cell projection organization",-2.0740912042,{"v":0.008431576714799,"d":"8.43E-03"},{"v":-0.2329860332,"d":"-0.233"},3,188,0.0159574468085106,"APOE,ID1,SPP1"]
["17_Summary","GO Biological Processes","GO:0043112","receptor metabolic process",-4.0845009348,{"v":8.2318806504295e-5,"d":"8.23E-05"},{"v":-1.7594350845,"d":"-1.759"},5,200,0.025,"APOE,FCER1G,CXCL8,GREM1,NSG1"]
["17_Member","GO Biological Processes","GO:0043112","receptor metabolic process",-4.0845009348,{"v":8.2318806504295e-5,"d":"8.23E-05"},{"v":-1.7594350845,"d":"-1.759"},5,200,0.025,"APOE,FCER1G,CXCL8,GREM1,NSG1"]
["17_Member","GO Biological Processes","GO:0031623","receptor internalization",-2.658665711,{"v":0.00219449345037743,"d":"2.19E-03"},{"v":-0.7120842831,"d":"-0.712"},3,116,0.0258620689655172,"FCER1G,CXCL8,GREM1"]
["17_Member","GO Biological Processes","GO:0045807","positive regulation of endocytosis",-2.3125045485,{"v":0.0048696242503155,"d":"4.87E-03"},{"v":-0.4134074304,"d":"-0.413"},3,154,0.0194805194805195,"APOE,FCER1G,GREM1"]
["17_Member","GO Biological Processes","GO:0006898","receptor-mediated endocytosis",-2.186077583,{"v":0.00651511996610641,"d":"6.52E-03"},{"v":-0.315493622,"d":"-0.315"},4,335,0.0119402985074627,"APOE,FCER1G,CXCL8,GREM1"]
["18_Summary","GO Biological Processes","GO:0043393","regulation of protein binding",-3.9655402541,{"v":0.00010825793678293,"d":"1.08E-04"},{"v":-1.6948320661,"d":"-1.695"},5,212,0.0235849056603774,"APOE,ID1,MMP9,CRTAC1,CTHRC1,OSR1,COL1A1,GPX2,DHRS2,GREM1"]
["18_Member","GO Biological Processes","GO:0043393","regulation of protein binding",-3.9655402541,{"$f":"10^(E323)","v":{"v":0.00010825793678293,"d":"1.08E-04"}},{"v":-1.6948320661,"d":"-1.695"},5,212,{"$f":"H323/I323","v":0.0235849056603774},"APOE,ID1,MMP9,CRTAC1,CTHRC1"]
["18_Member","GO Biological Processes","GO:0030857","negative regulation of epithelial cell differentiation",-3.6257279273,{"v":0.000236740234085159,"d":"2.37E-04"},{"v":-1.4485842741,"d":"-1.449"},3,54,0.0555555555555556,"ID1,MMP9,OSR1"]
["18_Member","GO Biological Processes","GO:0032092","positive regulation of protein binding",-3.046814145,{"v":0.000897812928607051,"d":"8.98E-04"},{"v":-0.9861163046,"d":"-0.986"},3,85,0.0352941176470588,"APOE,MMP9,CTHRC1"]
["18_Member","GO Biological Processes","GO:0051098","regulation of binding",-2.8735739963,{"v":0.00133790723938176,"d":"1.34E-03"},{"v":-0.8637785808,"d":"-0.864"},5,368,0.0135869565217391,"APOE,ID1,MMP9,CRTAC1,CTHRC1"]
["18_Member","GO Biological Processes","GO:0006979","response to oxidative stress",-2.4498713975,{"v":0.00354918471493143,"d":"3.55E-03"},{"v":-0.5317510422,"d":"-0.532"},5,461,0.0108459869848156,"APOE,COL1A1,GPX2,MMP9,DHRS2"]
["18_Member","GO Biological Processes","GO:0030856","regulation of epithelial cell differentiation",-2.1797946875,{"v":0.0066100586434757,"d":"6.61E-03"},{"v":-0.3106607928,"d":"-0.311"},3,172,0.0174418604651163,"ID1,MMP9,OSR1"]
["18_Member","GO Biological Processes","GO:0051099","positive regulation of binding",-2.1659996249,{"v":0.00682339283477628,"d":"6.82E-03"},{"v":-0.3011044834,"d":"-0.301"},3,174,0.0172413793103448,"APOE,MMP9,CTHRC1"]
["18_Member","GO Biological Processes","GO:0043534","blood vessel endothelial cell migration",-2.0615837125,{"v":0.00867793289540423,"d":"8.68E-03"},{"v":-0.2245310854,"d":"-0.225"},3,190,0.0157894736842105,"APOE,ID1,GREM1"]
["18_Member","GO Biological Processes","GO:0010631","epithelial cell migration",-2.0536545128,{"v":0.00883782682055963,"d":"8.84E-03"},{"v":-0.2192827245,"d":"-0.219"},4,366,0.0109289617486339,"APOE,ID1,MMP9,GREM1"]
["18_Member","GO Biological Processes","GO:0090132","epithelium migration",-2.0415408354,{"v":0.00908780845126808,"d":"9.09E-03"},{"v":-0.2111595297,"d":"-0.211"},4,369,0.010840108401084,"APOE,ID1,MMP9,GREM1"]
["18_Member","GO Biological Processes","GO:0090130","tissue migration",-2.0176579035,{"v":0.0096015665516202,"d":"9.60E-03"},{"v":-0.1938469876,"d":"-0.194"},4,375,0.0106666666666667,"APOE,ID1,MMP9,GREM1"]
["19_Summary","GO Biological Processes","GO:0052548","regulation of endopeptidase activity",-3.3863641279,{"v":0.000410805143066436,"d":"4.11E-04"},{"v":-1.2575929227,"d":"-1.258"},6,437,0.0137299771167048,"COL6A3,MMP9,SERPINE2,S100A8,S100A9,SPINK1,OSR1,APOE,PSCA"]
["19_Member","GO Biological Processes","GO:0052548","regulation of endopeptidase activity",-3.3863641279,{"v":0.000410805143066436,"d":"4.11E-04"},{"v":-1.2575929227,"d":"-1.258"},6,437,0.0137299771167048,"COL6A3,MMP9,SERPINE2,S100A8,S100A9,SPINK1"]
["19_Member","GO Biological Processes","GO:0043271","negative regulation of ion transport",-3.3742541788,{"v":0.000422421312093698,"d":"4.22E-04"},{"v":-1.2481071175,"d":"-1.248"},4,158,0.0253164556962025,"MMP9,SERPINE2,SPINK1,OSR1"]
["19_Member","GO Biological Processes","GO:0052547","regulation of peptidase activity",-3.2249573976,{"v":0.000595720578260905,"d":"5.96E-04"},{"v":-1.1167483514,"d":"-1.117"},6,469,0.0127931769722814,"COL6A3,MMP9,SERPINE2,S100A8,S100A9,SPINK1"]
["19_Member","GO Biological Processes","GO:0010951","negative regulation of endopeptidase activity",-2.587357918,{"v":0.00258608075274558,"d":"2.59E-03"},{"v":-0.649342734,"d":"-0.649"},4,258,0.0155038759689922,"COL6A3,MMP9,SERPINE2,SPINK1"]
["19_Member","GO Biological Processes","GO:0010466","negative regulation of peptidase activity",-2.5050087806,{"v":0.00312601616444431,"d":"3.13E-03"},{"v":-0.5803575581,"d":"-0.580"},4,272,0.0147058823529412,"COL6A3,MMP9,SERPINE2,SPINK1"]
["19_Member","GO Biological Processes","GO:0051051","negative regulation of transport",-2.2831827847,{"v":0.0052097539822418,"d":"5.21E-03"},{"v":-0.3902459754,"d":"-0.390"},5,505,0.0099009900990099,"APOE,MMP9,SERPINE2,SPINK1,OSR1"]
["19_Member","GO Biological Processes","GO:1902532","negative regulation of intracellular signal transduction",-2.0329516978,{"v":0.00926932911056018,"d":"9.27E-03"},{"v":-0.2052104883,"d":"-0.205"},5,581,0.00860585197934595,"APOE,MMP9,SERPINE2,SPINK1,PSCA"]
["19_Member","GO Biological Processes","GO:0045861","negative regulation of proteolysis",-2.0176579035,{"v":0.0096015665516202,"d":"9.60E-03"},{"v":-0.1938469876,"d":"-0.194"},4,375,0.0106666666666667,"COL6A3,MMP9,SERPINE2,SPINK1"]
["20_Summary","GO Biological Processes","GO:0071300","cellular response to retinoic acid",-3.3487612042,{"v":0.00044795954597578,"d":"4.48E-04"},{"v":-1.2278153366,"d":"-1.228"},3,67,0.0447761194029851,"COL1A1,TESC,OSR1,APOE,CXCL10,MMP9,SERPINE2,SPINK1"]
["20_Member","GO Biological Processes","GO:0071300","cellular response to retinoic acid",-3.3487612042,{"v":0.00044795954597578,"d":"4.48E-04"},{"v":-1.2278153366,"d":"-1.228"},3,67,0.0447761194029851,"COL1A1,TESC,OSR1"]
["20_Member","GO Biological Processes","GO:0043269","regulation of ion transport",-3.0242895703,{"v":0.000945606458320926,"d":"9.46E-04"},{"v":-0.9720089244,"d":"-0.972"},7,708,0.00988700564971751,"APOE,CXCL10,MMP9,SERPINE2,SPINK1,TESC,OSR1"]
["20_Member","GO Biological Processes","GO:0002028","regulation of sodium ion transport",-3.0031378466,{"v":0.000992800879905605,"d":"9.93E-04"},{"v":-0.9665128646,"d":"-0.967"},3,88,0.0340909090909091,"SERPINE2,TESC,OSR1"]
["20_Member","GO Biological Processes","GO:0032526","response to retinoic acid",-2.7471637471,{"v":0.00178993084834337,"d":"1.79E-03"},{"v":-0.7793064987,"d":"-0.779"},3,108,0.0277777777777778,"COL1A1,TESC,OSR1"]
["20_Member","GO Biological Processes","GO:0010959","regulation of metal ion transport",-2.7339762626,{"v":0.00184511626565057,"d":"1.85E-03"},{"v":-0.7697381558,"d":"-0.770"},5,396,0.0126262626262626,"CXCL10,SERPINE2,SPINK1,TESC,OSR1"]
["20_Member","GO Biological Processes","GO:1904062","regulation of cation transmembrane transport",-2.1245742109,{"v":0.00750629777861969,"d":"7.51E-03"},{"v":-0.2685437844,"d":"-0.269"},4,349,0.0114613180515759,"CXCL10,MMP9,TESC,OSR1"]