{"text_format":"3","workbook":"xlsx","n_sheets":2,"sheets":["A549-VS-A549_plus_INF_r.Possion","A549-VS-A549_plus_INF_r.Pos (2"],"not_rendered":{"defined_names":2},"read":"whole","date_system":"1900"}

{"sheet":"A549-VS-A549_plus_INF_r.Possion","index":0,"n_rows":15975,"n_cols":15,"rows_kept":4500,"cut":true,"bounds":{"rows_first":2000,"rows_last":500,"rows_between":2000,"halvings":0}}
["GeneID","Length","A549-Expression","A549_plus_INF_r-Expression","log2FoldChange(A549_plus_INF_r/A549)","FDR","Up/Down-Regulation(A549_plus_INF_r/A549)","Pvalue","Symbol","Cellular Component","Molecular Function","Biological Process","Kegg Orthology","Nr Description","Desc"]
[875,2583,0.01,8.81,9.78299820892041,{"v":1.63674973411765E-84,"d":"1.64E-84"},"Up",{"v":1.219314E-86,"d":"1.22E-86"},"CBS","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0020037//heme binding;GO:0072341//modified amino acid binding;GO:0042802//identical protein binding;GO:0031625//ubiquitin protein ligase binding;GO:1904047//S-adenosyl-L-methionine binding;GO:0070026//nitric oxide binding;GO:0042803//protein homodimerization activity;GO:0019825//oxygen binding;GO:0050421//nitrite reductase (NO-forming) activity;GO:0046872//metal ion binding;GO:0004122//cystathionine beta-synthase activity;GO:0070025//carbon monoxide binding;GO:0030170//pyridoxal phosphate binding;GO:0019899//enzyme binding","GO:0043418//homocysteine catabolic process;GO:0019346//transsulfuration;GO:0042262//DNA protection;GO:0006565//L-serine catabolic process;GO:0006563//L-serine metabolic process;GO:0019343//cysteine biosynthetic process via cystathionine;GO:0006535//cysteine biosynthetic process from serine;GO:0050667//homocysteine metabolic process;GO:0070814//hydrogen sulfide biosynthetic process;GO:0019344//cysteine biosynthetic process;GO:0019448//L-cysteine catabolic process","K01697//cystathionine beta-synthase [EC:4.2.1.22]","XP_009200453.1//cystathionine beta-synthase isoform X2 [Papio anubis];NP_001308001.1//cystathionine beta-synthase isoform 2 [Homo sapiens]","1//3;2//1"]
[54065,917,0.01,2.12,7.7279204545632,{"v":7.18055652489386e-07,"d":"7.18E-07"},"Up",{"v":1.164694E-7,"d":"1.16E-07"},"SMIM11A","NA","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K06245//laminin, beta 4;K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K01064//wingless-type MMTV integration site family, member 9","BAG64432.1//unnamed protein product [Homo sapiens]",4]
[30009,2589,0.01,1.91,7.57742882803575,{"v":3.68634383257919e-18,"d":"3.69E-18"},"Up",{"v":2.04002e-19,"d":"2.04E-19"},"TBX21","GO:0005634//nucleus;GO:0043025//neuronal cell body","GO:0043565//sequence-specific DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0001227//transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding","GO:0006355//regulation of transcription, DNA-templated;GO:0045580//regulation of T cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0071310//cellular response to organic substance;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0032703//negative regulation of interleukin-2 production;GO:2000552//negative regulation of T-helper 2 cell cytokine production;GO:0072676//lymphocyte migration;GO:0045892//negative regulation of transcription, DNA-templated;GO:2000329//negative regulation of T-helper 17 cell lineage commitment;GO:0006351//transcription, DNA-templated;GO:2000320//negative regulation of T-helper 17 cell differentiation;GO:0048304//positive regulation of isotype switching to IgG isotypes;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0007275//multicellular organism development;GO:0030217//T cell differentiation;GO:0009615//response to virus","K10166//T-box protein 21","NP_037483.1//T-box transcription factor TBX21 [Homo sapiens]","1//3"]
[10537,1006,0.01,1.88,7.55458885167764,{"v":7.18332894054054e-07,"d":"7.18E-07"},"Up",{"v":1.164694E-7,"d":"1.16E-07"},"UBD","GO:0005634//nucleus;GO:0005829//cytosol;GO:0016235//aggresome;GO:0001650//fibrillar center;GO:0005737//cytoplasm","GO:0070628//proteasome binding","GO:0043687//post-translational protein modification;GO:0016567//protein ubiquitination;GO:0032446//protein modification by small protein conjugation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:1901990//regulation of mitotic cell cycle phase transition;GO:0043065//positive regulation of apoptotic process;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006508//proteolysis;GO:0034612//response to tumor necrosis factor;GO:0034341//response to interferon-gamma;GO:0070842//aggresome assembly;GO:0043011//myeloid dendritic cell differentiation","K12157//ubiquitin D","NP_006389.2//ubiquitin D [Homo sapiens]","3//A2MP1"]
[375593,1358,0.01,1.73,7.43462822763673,{"v":1.39959159864407E-8,"d":"1.40E-08"},"Up",{"v":1.809288E-9,"d":"1.81E-09"},"TRIM73","GO:0005829//cytosol;GO:0005622//intracellular","GO:0008270//zinc ion binding","NA","K12024//tripartite motif-containing protein 50/73/74","NP_944606.2//tripartite motif-containing protein 73 [Homo sapiens]","3//A2MP1"]
[128653,631,0.01,1.48,7.20945336562895,0.00087267341128484,"Up",2.41086E-4,"C20orf141","GO:0016021//integral component of membrane","NA","NA","NA","NP_542777.1//uncharacterized protein C20orf141 [Homo sapiens]","1//3;2//1"]
[2633,3050,0.05,6.79,7.08533966935737,{"v":4.31300366518519e-73,"d":"4.31E-73"},"Up",{"v":3.64502e-75,"d":"3.65E-75"},"GBP1","GO:0005829//cytosol;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0000139//Golgi membrane","GO:0019955//cytokine binding;GO:0042802//identical protein binding;GO:0019003//GDP binding;GO:0042803//protein homodimerization activity;GO:0003924//GTPase activity;GO:0003779//actin binding;GO:0051879//Hsp90 protein binding;GO:0005525//GTP binding;GO:0019899//enzyme binding;GO:0030507//spectrin binding","GO:0060333//interferon-gamma-mediated signaling pathway;GO:1903077//negative regulation of protein localization to plasma membrane;GO:1900025//negative regulation of substrate adhesion-dependent cell spreading;GO:0051607//defense response to virus;GO:0051260//protein homooligomerization;GO:1900041//negative regulation of interleukin-2 secretion;GO:1903076//regulation of protein localization to plasma membrane;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0050860//negative regulation of T cell receptor signaling pathway;GO:0050848//regulation of calcium-mediated signaling","K20899//guanylate-binding protein 1/3/4/7","NP_002044.2//guanylate-binding protein 1 [Homo sapiens]","2//1"]
[29126,3083,0.05,5.95,6.89481776330794,{"v":1.63225608717949e-64,"d":"1.63E-64"},"Up",{"v":1.59404e-66,"d":"1.59E-66"},"CD274","GO:0070062//extracellular exosome;GO:0012505//endomembrane system;GO:0009897//external side of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","NA","GO:0046007//negative regulation of activated T cell proliferation;GO:0007165//signal transduction;GO:0030335//positive regulation of cell migration;GO:0032693//negative regulation of interleukin-10 production;GO:0034097//response to cytokine;GO:0042102//positive regulation of T cell proliferation;GO:0007166//cell surface receptor signaling pathway;GO:0031295//T cell costimulation;GO:1903556//negative regulation of tumor necrosis factor superfamily cytokine production;GO:1901998//toxin transport;GO:1905404//positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process;GO:0006955//immune response;GO:0032689//negative regulation of interferon-gamma production;GO:2001181//positive regulation of interleukin-10 secretion","K06745//programmed cell death 1 ligand 1","NP_054862.1//programmed cell death 1 ligand 1 isoform a precursor [Homo sapiens];NP_001300958.1//programmed cell death 1 ligand 1 isoform c precursor [Homo sapiens];NP_001254635.1//programmed cell death 1 ligand 1 isoform b precursor [Homo sapiens]","1//3;3//A2MP1"]
[101060321,2090,0.01,0.86,6.4262647547021,{"v":1.37640862379897e-06,"d":"1.38E-06"},"Up",{"v":2.33164e-07,"d":"2.33E-07"},"TBC1D3G","GO:0012505//endomembrane system;GO:0005622//intracellular;GO:0005886//plasma membrane","GO:0017137//Rab GTPase binding;GO:0005096//GTPase activator activity","GO:0006886//intracellular protein transport;GO:0090630//activation of GTPase activity;GO:0031338//regulation of vesicle fusion","K20134//TBC1 domain family member 3","NP_001278391.1//TBC1 domain family member 3G [Homo sapiens]","1//3"]
[3702,4366,0.01,0.83,6.37503943134693,{"v":1.74216421461847e-13,"d":"1.74E-13"},"Up",{"v":1.357828e-14,"d":"1.36E-14"},"ITK","GO:0005634//nucleus;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0005829//cytosol;GO:0005911//cell-cell junction","GO:0046872//metal ion binding;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005524//ATP binding","GO:0042110//T cell activation;GO:0007165//signal transduction;GO:0038083//peptidyl-tyrosine autophosphorylation;GO:0050852//T cell receptor signaling pathway;GO:0042127//regulation of cell proliferation;GO:0035556//intracellular signal transduction;GO:0032609//interferon-gamma production;GO:0001816//cytokine production;GO:0006968//cellular defense response;GO:0002250//adaptive immune response;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0001865//NK T cell differentiation;GO:0007202//activation of phospholipase C activity;GO:0032633//interleukin-4 production;GO:0045087//innate immune response","K07363//IL2-inducible T-cell kinase [EC:2.7.10.2]","NP_005537.3//tyrosine-protein kinase ITK/TSK [Homo sapiens]","3//A2MP1"]
[3627,1227,0.01,0.8,6.32192809488736,0.0008720805625,"Up",2.41086E-4,"CXCL10","GO:0005615//extracellular space;GO:0009897//external side of plasma membrane;GO:0005623//cell;GO:0005576//extracellular region","GO:0048248//CXCR3 chemokine receptor binding;GO:0008603//cAMP-dependent protein kinase regulator activity;GO:0008201//heparin binding;GO:0005102//receptor binding;GO:0008009//chemokine activity","GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0042127//regulation of cell proliferation;GO:0071222//cellular response to lipopolysaccharide;GO:0007166//cell surface receptor signaling pathway;GO:0010332//response to gamma radiation;GO:2000406//positive regulation of T cell migration;GO:0043950//positive regulation of cAMP-mediated signaling;GO:0007165//signal transduction;GO:0010996//response to auditory stimulus;GO:0090026//positive regulation of monocyte chemotaxis;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0070098//chemokine-mediated signaling pathway;GO:0031640//killing of cells of other organism;GO:0033280//response to vitamin D;GO:0008015//blood circulation;GO:0045662//negative regulation of myoblast differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0010819//regulation of T cell chemotaxis;GO:1901740//negative regulation of myoblast fusion;GO:0032496//response to lipopolysaccharide;GO:0030816//positive regulation of cAMP metabolic process;GO:0010818//T cell chemotaxis;GO:0006935//chemotaxis;GO:0007186//G-protein coupled receptor signaling pathway;GO:0016525//negative regulation of angiogenesis;GO:0009409//response to cold;GO:0051607//defense response to virus;GO:0007267//cell-cell signaling;GO:0007517//muscle organ development;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0034605//cellular response to heat;GO:0006954//inflammatory response;GO:1901509//regulation of endothelial tube morphogenesis;GO:0006952//defense response;GO:0006955//immune response;GO:0042118//endothelial cell activation;GO:0008284//positive regulation of cell proliferation","K12671//C-X-C motif chemokine 10","NP_001556.2//C-X-C motif chemokine 10 precursor [Homo sapiens]","3//A2MP1"]
[729262,3292,0.01,0.75,6.22881869049588,{"v":7.26196681690141e-09,"d":"7.26E-09"},"Up",{"v":9.03768e-10,"d":"9.04E-10"},"NUTM2B","NA","NA","NA","K17602//YLP motif-containing protein 1;K13911//basic salivary proline-rich protein 1/2","NP_001265424.1//NUT family member 2B [Homo sapiens]","1//3"]
[2944,1266,0.01,0.73,6.18982455888002,0.00165514371232289,"*",0.000482638,"GSTM1","NA","NA","NA","K00799//glutathione S-transferase [EC:2.5.1.18]","XP_009244998.1//PREDICTED: glutathione S-transferase Mu 1 isoform X1 [Pongo abelii]","3//A2MP1;2//1"]
[684,1048,0.01,0.71,6.14974711950468,5.90904806961178E-3,"*",1.934294E-3,"BST2","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0016324//apical plasma membrane;GO:0031225//anchored component of membrane;GO:0035577//azurophil granule membrane;GO:0009986//cell surface;GO:0045121//membrane raft;GO:0005887//integral component of plasma membrane;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005771//multivesicular body;GO:0005886//plasma membrane","GO:0003723//RNA binding;GO:0008191//metalloendopeptidase inhibitor activity;GO:0042802//identical protein binding;GO:0004871//signal transducer activity;GO:0042803//protein homodimerization activity","GO:0035456//response to interferon-beta;GO:0060337//type I interferon signaling pathway;GO:0032956//regulation of actin cytoskeleton organization;GO:0008283//cell proliferation;GO:0006959//humoral immune response;GO:0034341//response to interferon-gamma;GO:0045071//negative regulation of viral genome replication;GO:1901253//negative regulation of intracellular transport of viral material;GO:0043312//neutrophil degranulation;GO:0045087//innate immune response;GO:0030308//negative regulation of cell growth;GO:0007267//cell-cell signaling;GO:0051607//defense response to virus;GO:0030336//negative regulation of cell migration;GO:0002737//negative regulation of plasmacytoid dendritic cell cytokine production;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0035455//response to interferon-alpha;GO:0007275//multicellular organism development;GO:0009615//response to virus;GO:0042113//B cell activation","K06731//bone marrow stromal cell antigen 2","NP_004326.1//bone marrow stromal antigen 2 precursor [Homo sapiens]","3//A2MP1"]
[121793,859,0.01,0.66,6.04439411935845,0.0379992175965665,"*",0.0155194,"TEX29","GO:0016021//integral component of membrane","NA","NA","NA","XP_016875876.1//PREDICTED: testis-expressed sequence 29 protein isoform X1 [Homo sapiens];NP_001290062.1//testis-expressed protein 29 isoform 1 [Homo sapiens]","1//3;2//1"]
[733,888,0.01,0.65,6.02236781302845,0.0205874186733167,"*",7.75218E-3,"C8G","NA","NA","NA","K03999//complement component 8 subunit gamma","XP_016817690.1//PREDICTED: complement component C8 gamma chain [Pan troglodytes]","2//1"]
[100293534,5427,0.01,0.61,5.93073733756289,{"v":4.96403703629893e-12,"d":"4.96E-12"},"Up",{"v":4.36614e-13,"d":"4.37E-13"},"C4B_2","GO:0070062//extracellular exosome;GO:0005788//endoplasmic reticulum lumen;GO:0030425//dendrite;GO:0030424//axon;GO:0005615//extracellular space;GO:0072562//blood microparticle;GO:0044216//other organism cell;GO:0030054//cell junction;GO:0043025//neuronal cell body;GO:0005576//extracellular region;GO:0045202//synapse;GO:0005886//plasma membrane","GO:0001848//complement binding;GO:0004252//serine-type endopeptidase activity;GO:0030246//carbohydrate binding;GO:0004866//endopeptidase inhibitor activity;GO:0001849//complement component C1q binding","GO:0043687//post-translational protein modification;GO:0030449//regulation of complement activation;GO:0006956//complement activation;GO:0032490//detection of molecule of bacterial origin;GO:0006954//inflammatory response;GO:0044267//cellular protein metabolic process;GO:0006958//complement activation, classical pathway;GO:2000427//positive regulation of apoptotic cell clearance;GO:0045087//innate immune response;GO:0008228//opsonization","K03989//complement component 4","NP_001229752.1//complement C4-B-like preproprotein [Homo sapiens]","2//1"]
[653604,457,0.01,0.58,5.85798099512757,0.226747397218422,"*",0.1245166,"HIST2H3D","NA","NA","NA","K11253//histone H3","XP_012669845.1//PREDICTED: uncharacterized protein LOC105888650 [Clupea harengus]","2//1"]
[5196,878,0.01,0.57,5.83289001416474,0.0380050430170167,"*",0.0155194,"PF4","GO:0031093//platelet alpha granule lumen;GO:0005615//extracellular space;GO:0020005//symbiont-containing vacuole membrane;GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0097679//other organism cytoplasm","GO:0048248//CXCR3 chemokine receptor binding;GO:0045236//CXCR chemokine receptor binding;GO:0008201//heparin binding;GO:0008009//chemokine activity","GO:0010744//positive regulation of macrophage derived foam cell differentiation;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0045347//negative regulation of MHC class II biosynthetic process;GO:0042127//regulation of cell proliferation;GO:0032496//response to lipopolysaccharide;GO:0030168//platelet activation;GO:0030816//positive regulation of cAMP metabolic process;GO:0051873//killing by host of symbiont cells;GO:0032760//positive regulation of tumor necrosis factor production;GO:0002576//platelet degranulation;GO:0045653//negative regulation of megakaryocyte differentiation;GO:0045651//positive regulation of macrophage differentiation;GO:0043950//positive regulation of cAMP-mediated signaling;GO:0007186//G-protein coupled receptor signaling pathway;GO:0090023//positive regulation of neutrophil chemotaxis;GO:0042832//defense response to protozoan;GO:0016525//negative regulation of angiogenesis;GO:0070098//chemokine-mediated signaling pathway;GO:0030595//leukocyte chemotaxis;GO:0031640//killing of cells of other organism;GO:0045652//regulation of megakaryocyte differentiation;GO:0010628//positive regulation of gene expression;GO:0006954//inflammatory response;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006955//immune response;GO:0019221//cytokine-mediated signaling pathway;GO:0045918//negative regulation of cytolysis","K05407//platelet factor 4","XP_003265787.1//PREDICTED: platelet factor 4 [Nomascus leucogenys]","3//A2MP1"]
[8968,466,0.01,0.56,5.8073549220576,0.226876715911943,"*",0.1245166,"HIST1H3F","GO:0005634//nucleus;GO:0000786//nucleosome","GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity","GO:0006334//nucleosome assembly;GO:0006352//DNA-templated transcription, initiation","K11253//histone H3","XP_012890639.1//PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein LOC106000001 [Dipodomys ordii]","2//1"]
[100529251,794,0.01,0.56,5.8073549220576,0.0702168946236559,"*",0.0310688,"CKLF-CMTM1","GO:0016021//integral component of membrane","NA","NA","NA","NP_001189438.1//CKLF-CMTM1 protein isoform 3 [Homo sapiens];NP_001191027.1//CKLF-CMTM1 protein isoform 2 [Homo sapiens];NP_001191028.1//CKLF-CMTM1 protein isoform 1 [Homo sapiens]","1//3"]
[84648,617,0.01,0.55,5.78135971352466,0.127558204134035,"*",0.062198,"LCE3D","GO:0005829//cytosol;GO:0001533//cornified envelope;GO:0005737//cytoplasm","GO:0005198//structural molecule activity","GO:0018149//peptide cross-linking;GO:0030216//keratinocyte differentiation;GO:0070268//cornification","NA","NP_115952.1//late cornified envelope protein 3D [Homo sapiens]","1//3"]
[3394,2678,0.06,3.22,5.74595437739346,{"v":1.48962552656587e-28,"d":"1.49E-28"},"Up",{"v":4.31762e-30,"d":"4.32E-30"},"IRF8","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003705//transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0060337//type I interferon signaling pathway;GO:0042832//defense response to protozoan;GO:0030099//myeloid cell differentiation;GO:0071222//cellular response to lipopolysaccharide;GO:0006351//transcription, DNA-templated;GO:0042742//defense response to bacterium;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0071346//cellular response to interferon-gamma;GO:0032735//positive regulation of interleukin-12 production;GO:0044130//negative regulation of growth of symbiont in host;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006955//immune response;GO:0032729//positive regulation of interferon-gamma production;GO:0006909//phagocytosis","K10155//interferon regulatory factor 8","XP_017716051.1//PREDICTED: interferon regulatory factor 8 [Rhinopithecus bieti]","2//1"]
[54567,3420,0.02,0.88,5.4594316186373,{"v":6.51646728490352e-10,"d":"6.52E-10"},"Up",{"v":7.18794e-11,"d":"7.19E-11"},"DLL4","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005509//calcium ion binding;GO:0005112//Notch binding","GO:0003222//ventricular trabecula myocardium morphogenesis;GO:0090051//negative regulation of cell migration involved in sprouting angiogenesis;GO:0003209//cardiac atrium morphogenesis;GO:0072554//blood vessel lumenization;GO:0045747//positive regulation of Notch signaling pathway;GO:0003344//pericardium morphogenesis;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0007601//visual perception;GO:0010629//negative regulation of gene expression;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0061074//regulation of neural retina development;GO:0060579//ventral spinal cord interneuron fate commitment;GO:0061314//Notch signaling involved in heart development;GO:0008285//negative regulation of cell proliferation;GO:1903588//negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis;GO:0007165//signal transduction;GO:0001525//angiogenesis;GO:0035912//dorsal aorta morphogenesis;GO:0010596//negative regulation of endothelial cell migration;GO:0010628//positive regulation of gene expression;GO:0003208//cardiac ventricle morphogenesis;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:2000179//positive regulation of neural precursor cell proliferation;GO:0001974//blood vessel remodeling;GO:0008015//blood circulation;GO:0007220//Notch receptor processing;GO:0045746//negative regulation of Notch signaling pathway;GO:0030217//T cell differentiation;GO:0007219//Notch signaling pathway;GO:0001569//branching involved in blood vessel morphogenesis;GO:0050767//regulation of neurogenesis","K06051//delta","EAW92466.1//delta-like 4 (Drosophila) [Homo sapiens]","3//A2MP1"]
[390940,938,0.01,0.43,5.4262647547021,0.226308814245079,"*",0.1245166,"PINLYP","GO:0005576//extracellular region","GO:0004859//phospholipase inhibitor activity","NA","K03985//plasminogen activator, urokinase receptor","NP_001180550.1//phospholipase A2 inhibitor and Ly6/PLAUR domain-containing protein isoform 1 [Homo sapiens];A6NC86.3//RecName: Full=phospholipase A2 inhibitor and Ly6/PLAUR domain-containing protein; Flags: Precursor;AAC99796.1//R28379_1, partial [Homo sapiens]","1//3"]
[51463,2217,0.01,0.42,5.39231742277876,0.00165549912218166,"*",0.000482638,"GPR89B","GO:0032580//Golgi cisterna membrane;GO:0016021//integral component of membrane;GO:0030660//Golgi-associated vesicle membrane","GO:0008308//voltage-gated anion channel activity;GO:0004871//signal transducer activity","GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043588//skin development;GO:0051452//intracellular pH reduction;GO:0015031//protein transport","K22193//golgi pH regulator","NP_057418.1//Golgi pH regulator B isoform 1 [Homo sapiens];XP_007975517.1//PREDICTED: Golgi pH regulator A isoform X2 [Chlorocebus sabaeus]","4;1//3"]
[6354,815,0.01,0.41,5.35755200461808,0.127672944230275,"*",0.062198,"CCL7","GO:0005615//extracellular space","GO:0031727//CCR2 chemokine receptor binding;GO:0008009//chemokine activity;GO:0031726//CCR1 chemokine receptor binding;GO:0048020//CCR chemokine receptor binding","GO:0043547//positive regulation of GTPase activity;GO:0071356//cellular response to tumor necrosis factor;GO:0071346//cellular response to interferon-gamma;GO:0071347//cellular response to interleukin-1;GO:0002548//monocyte chemotaxis;GO:0007186//G-protein coupled receptor signaling pathway;GO:0048247//lymphocyte chemotaxis;GO:0048245//eosinophil chemotaxis;GO:2000503//positive regulation of natural killer cell chemotaxis;GO:0030593//neutrophil chemotaxis;GO:0070098//chemokine-mediated signaling pathway;GO:0008360//regulation of cell shape;GO:0006954//inflammatory response;GO:0007010//cytoskeleton organization;GO:0006955//immune response;GO:0070374//positive regulation of ERK1 and ERK2 cascade","K05509//C-C motif chemokine 7","XP_003818055.1//PREDICTED: C-C motif chemokine 7 [Pan paniscus]","3//A2MP1"]
[6019,619,0.01,0.41,5.35755200461808,0.226644048359161,"*",0.1245166,"RLN2","GO:0005576//extracellular region","GO:0005179//hormone activity","GO:0007565//female pregnancy;GO:0045766//positive regulation of angiogenesis;GO:0050790//regulation of catalytic activity;GO:0010628//positive regulation of gene expression;GO:0030819//positive regulation of cAMP biosynthetic process","K21998//relaxin 1/2","NP_005050.2//prorelaxin H2 isoform 2 precursor [Homo sapiens];NP_604390.1//prorelaxin H2 isoform 1 preproprotein [Homo sapiens]","1//3;3//A2MP1;2//1"]
[3383,3249,1.06,42.59,5.32837855998714,0,"Up",0,"ICAM1","GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0005925//focal adhesion;GO:0009897//external side of plasma membrane;GO:0001772//immunological synapse;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0045121//membrane raft;GO:0016021//integral component of membrane","GO:0005178//integrin binding;GO:0004872//receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0001618//virus receptor activity","GO:0007159//leukocyte cell-cell adhesion;GO:0033627//cell adhesion mediated by integrin;GO:0002291//T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell;GO:1900027//regulation of ruffle assembly;GO:0002693//positive regulation of cellular extravasation;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0030155//regulation of cell adhesion;GO:0002457//T cell antigen processing and presentation;GO:0050900//leukocyte migration;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:0071333//cellular response to glucose stimulus;GO:1990830//cellular response to leukemia inhibitory factor;GO:0007155//cell adhesion;GO:0044406//adhesion of symbiont to host;GO:0022614//membrane to membrane docking;GO:0061028//establishment of endothelial barrier;GO:0002438//acute inflammatory response to antigenic stimulus;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0046813//receptor-mediated virion attachment to host cell","K06490//intercellular adhesion molecule 1","NP_000192.2//intercellular adhesion molecule 1 precursor [Homo sapiens]","2//1"]
[432355,593,0.01,0.4,5.32192809488736,0.392731322221126,"*",0.249274,"SLURP2","GO:0005615//extracellular space","GO:0033130//acetylcholine receptor binding;GO:0030548//acetylcholine receptor regulator activity","GO:0099601//regulation of neurotransmitter receptor activity;GO:0095500//acetylcholine receptor signaling pathway","K13909//mucin-7","NP_803253.1//ly-6/neurotoxin-like protein 1 isoform b precursor [Homo sapiens]","1//3;2//1"]
[116071,1991,0.78,30.44,5.2863504246413,{"v":1.65392916705882e-194,"d":"1.65E-194"},"Up",{"v":3.52032e-197,"d":"3.52E-197"},"BATF2","GO:0005634//nucleus","GO:0003677//DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0042832//defense response to protozoan;GO:0006351//transcription, DNA-templated;GO:0043011//myeloid dendritic cell differentiation","K09034//ATF-like basic leucine zipper transcriptional factor","NP_001287736.1//basic leucine zipper transcriptional factor ATF-like 2 isoform 2 [Homo sapiens];EAW74331.1//basic leucine zipper transcription factor, ATF-like 2, isoform CRA_b [Homo sapiens];NP_612465.3//basic leucine zipper transcriptional factor ATF-like 2 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[163688,1101,0.01,0.39,5.28540221886225,0.0702367692046419,"*",0.0310688,"CALML6","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0005509//calcium ion binding","NA","K02183//calmodulin","NP_619650.2//calmodulin-like protein 6 isoform 1 [Homo sapiens];XP_011282712.2//PREDICTED: calmodulin-like protein 6, partial [Felis catus]","1//3;3//A2MP1"]
[349334,1251,0.01,0.38,5.24792751344359,0.0702765521382045,"*",0.0310688,"FOXD4L4","GO:0005634//nucleus","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding","GO:0009653//anatomical structure morphogenesis;GO:0030154//cell differentiation;GO:0006351//transcription, DNA-templated","K09397//forkhead box protein D","NP_954714.2//forkhead box protein D4-like 4 [Homo sapiens]","3//A2MP1"]
[388394,1110,0.01,0.37,5.20945336562895,0.0702865049143181,"*",0.0310688,"RPRML","GO:0016021//integral component of membrane","NA","NA","K10128//reprimo, TP53-dependent G2 arrest mediator candidate","XP_021784073.1//reprimo-like protein [Papio anubis]",4]
[100131187,564,0.01,0.37,5.20945336562895,0.226180141960428,"*",0.1245166,"TSTD1","NA","NA","NA","K06089//junctional adhesion molecule 1;K01011//thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]","XP_003780801.1//PREDICTED: LOW QUALITY PROTEIN: thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 1 [Pongo abelii];XP_003308600.1//PREDICTED: thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 1 isoform X1 [Pan troglodytes];XP_003308601.1//PREDICTED: thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 1 isoform X2 [Pan troglodytes]","1//3"]
[51052,264,0.01,0.36,5.16992500144231,0.649465306175656,"*",0.499032,"PRLH","GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0005184//neuropeptide hormone activity;GO:0031861//prolactin-releasing peptide receptor binding;GO:0005179//hormone activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0048483//autonomic nervous system development;GO:0042755//eating behavior;GO:0032868//response to insulin;GO:0040014//regulation of multicellular organism growth;GO:0002021//response to dietary excess;GO:0001894//tissue homeostasis;GO:0006112//energy reserve metabolic process;GO:0045444//fat cell differentiation;GO:0009749//response to glucose;GO:0002023//reduction of food intake in response to dietary excess;GO:0006629//lipid metabolic process","K05269//Prolactin-releasing peptide","XP_003813153.2//PREDICTED: prolactin-releasing peptide [Pan paniscus]","1//3"]
[90019,1569,0.01,0.36,5.16992500144231,0.0205839965625,"*",7.75218E-3,"SYT8","GO:0030672//synaptic vesicle membrane;GO:0016021//integral component of membrane;GO:0001669//acrosomal vesicle;GO:0005886//plasma membrane","GO:0005544//calcium-dependent phospholipid binding;GO:0030276//clathrin binding;GO:0005509//calcium ion binding;GO:0019905//syntaxin binding;GO:0048306//calcium-dependent protein binding","GO:0006906//vesicle fusion;GO:0048488//synaptic vesicle endocytosis;GO:0007340//acrosome reaction;GO:0048791//calcium ion-regulated exocytosis of neurotransmitter;GO:0017158//regulation of calcium ion-dependent exocytosis","K19908//synaptotagmin-8","NP_612634.3//synaptotagmin-8 isoform 2 [Homo sapiens];NP_001277261.1//synaptotagmin-8 isoform 1 [Homo sapiens];NP_001277263.1//synaptotagmin-8 isoform 4 [Homo sapiens];NP_001277262.1//synaptotagmin-8 isoform 3 [Homo sapiens]","1//3;4"]
[4070,2080,0.01,0.35,5.12928301694497,0.00591130904074995,"*",1.934294E-3,"TACSTD2","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0009925//basal plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005829//cytosol;GO:0016328//lateral plasma membrane","GO:0004872//receptor activity","GO:0090191//negative regulation of branching involved in ureteric bud morphogenesis;GO:1900025//negative regulation of substrate adhesion-dependent cell spreading;GO:0007601//visual perception;GO:0007166//cell surface receptor signaling pathway;GO:0050678//regulation of epithelial cell proliferation;GO:0010633//negative regulation of epithelial cell migration;GO:0098609//cell-cell adhesion;GO:0060675//ureteric bud morphogenesis;GO:0051497//negative regulation of stress fiber assembly;GO:0008283//cell proliferation;GO:2000146//negative regulation of cell motility;GO:2000738//positive regulation of stem cell differentiation;GO:1900028//negative regulation of ruffle assembly","K17288//tumor-associated calcium signal transducer 2","XP_003265191.1//PREDICTED: tumor-associated calcium signal transducer 2 [Nomascus leucogenys]","2//1"]
[4493,519,0.01,0.34,5.08746284125034,0.392847560773481,"*",0.249274,"MT1E","NA","NA","NA","K14739//metallothionein 1/2","XP_009194736.1//metallothionein-1E isoform X2 [Papio anubis]","3//A2MP1"]
[165904,3067,0.01,0.34,5.08746284125034,4.60541472157051E-4,"Up",1.204258E-4,"XIRP1","GO:0001725//stress fiber;GO:0005925//focal adhesion;GO:0030054//cell junction;GO:0031941//filamentous actin","GO:0003779//actin binding;GO:0003723//RNA binding","GO:0030036//actin cytoskeleton organization;GO:0032091//negative regulation of protein binding;GO:0007507//heart development","K16628//collagen, type VII, alpha;K17582//antigen KI-67","NP_001185550.1//xin actin-binding repeat-containing protein 1 isoform 2 [Homo sapiens];NP_919269.2//xin actin-binding repeat-containing protein 1 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[101928917,1184,0.01,0.33,5.04439411935845,0.127722181771436,"*",0.062198,"HSFX3","GO:0005634//nucleus","GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0006351//transcription, DNA-templated","K09415//heat shock transcription factor 2;K07612//gap junction alpha-3 protein;K09414//heat shock transcription factor 1;K15694//RING finger protein 43 [EC:2.3.2.27];K16482//centriolar protein POC1","NP_001310008.1//heat shock transcription factor, X-linked member 3 [Homo sapiens]","1//3"]
[727832,4013,0.01,0.33,5.04439411935845,{"v":6.69914478792959e-05,"d":"6.70E-05"},"Up",{"v":1.500954E-5,"d":"1.50E-05"},"GOLGA6L6","NA","NA","NA","K18626//trichohyalin;K20358//golgin subfamily A member 2","NP_001138476.2//golgin subfamily A member 6-like protein 6 [Homo sapiens]","2//1"]
[6441,1299,0.01,0.31,4.95419631038688,0.0702069615504315,"*",0.0310688,"SFTPD","GO:0005581//collagen trimer","GO:0005201//extracellular matrix structural constituent","NA","K06236//collagen, type I, alpha","XP_020559369.1//collagen alpha-1(I) chain-like [Oryzias latipes]",4]
[3266,826,0.01,0.3,4.90689059560852,0.226283068077361,"*",0.1245166,"ERAS","GO:0016020//membrane;GO:0005886//plasma membrane","GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0007165//signal transduction","K17196//GTPase Eras","NP_853510.1//GTPase ERas precursor [Homo sapiens]","3//A2MP1"]
[57817,598,0.01,0.29,4.85798099512757,0.392112543180699,"*",0.249274,"HAMP","GO:0045179//apical cortex;GO:0005615//extracellular space;GO:0005623//cell;GO:0005576//extracellular region;GO:0014704//intercalated disc","GO:0097690//iron channel inhibitor activity;GO:0005102//receptor binding;GO:0005179//hormone activity","GO:0071481//cellular response to X-ray;GO:0006879//cellular iron ion homeostasis;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:1904255//negative regulation of iron channel activity;GO:0097421//liver regeneration;GO:0071222//cellular response to lipopolysaccharide;GO:0002092//positive regulation of receptor internalization;GO:0071356//cellular response to tumor necrosis factor;GO:0045471//response to ethanol;GO:1902916//positive regulation of protein polyubiquitination;GO:0071354//cellular response to interleukin-6;GO:0033189//response to vitamin A;GO:0010043//response to zinc ion;GO:0010039//response to iron ion;GO:0031640//killing of cells of other organism;GO:0032413//negative regulation of ion transmembrane transporter activity;GO:0061051//positive regulation of cell growth involved in cardiac muscle cell development;GO:0050829//defense response to Gram-negative bacterium;GO:0042742//defense response to bacterium;GO:2000646//positive regulation of receptor catabolic process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0050830//defense response to Gram-positive bacterium;GO:1904039//negative regulation of ferrous iron export;GO:0036017//response to erythropoietin;GO:0050832//defense response to fungus;GO:0060586//multicellular organismal iron ion homeostasis;GO:0006953//acute-phase response;GO:1904479//negative regulation of intestinal absorption;GO:0007568//aging;GO:1903413//cellular response to bile acid;GO:0034760//negative regulation of iron ion transmembrane transport;GO:1990641//response to iron ion starvation;GO:0006955//immune response","NA","NP_066998.1//hepcidin preproprotein [Homo sapiens]","3//A2MP1"]
[100996741,3409,0.01,0.28,4.8073549220576,0.000872278089241223,"Up",2.41086E-4,"LOC100996741","NA","NA","NA","NA","XP_011817615.1//PREDICTED: protein FAM231A/C-like [Colobus angolensis palliatus]","1//3"]
[2352,948,0.01,0.28,4.8073549220576,0.226721551168357,"*",0.1245166,"FOLR3","GO:1904724//tertiary granule lumen;GO:0016020//membrane;GO:0035580//specific granule lumen;GO:0019898//extrinsic component of membrane;GO:0005576//extracellular region","GO:0005542//folic acid binding","GO:0015884//folic acid transport;GO:0043312//neutrophil degranulation","K13649//folate receptor","XP_008018204.1//PREDICTED: folate receptor gamma isoform X1 [Chlorocebus sabaeus];P41439.1//RecName: Full=Folate receptor gamma; Short=FR-gamma; AltName: Full=Folate receptor 3; Flags: Precursor","1//3;3//A2MP1"]
[200931,1455,0.01,0.28,4.8073549220576,0.0702268305079949,"*",0.0310688,"SLC51A","GO:0043234//protein complex;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane","GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0005215//transporter activity","GO:0006810//transport;GO:0015721//bile acid and bile salt transport","K14360//organic solute transporter subunit alpha","NP_689885.4//organic solute transporter subunit alpha [Homo sapiens]",5]
[3659,3557,11.45,291.45,4.66982889820956,0,"Up",0,"IRF1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0000790//nuclear chromatin;GO:0005737//cytoplasm","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:0043565//sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0060337//type I interferon signaling pathway;GO:0034124//regulation of MyD88-dependent toll-like receptor signaling pathway;GO:0032481//positive regulation of type I interferon production;GO:0071260//cellular response to mechanical stimulus;GO:0007596//blood coagulation;GO:2000564//regulation of CD8-positive, alpha-beta T cell proliferation;GO:0007050//cell cycle arrest;GO:0045893//positive regulation of transcription, DNA-templated;GO:0043374//CD8-positive, alpha-beta T cell differentiation;GO:0035458//cellular response to interferon-beta;GO:0050776//regulation of immune response;GO:0008285//negative regulation of cell proliferation;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045084//positive regulation of interleukin-12 biosynthetic process;GO:0032728//positive regulation of interferon-beta production;GO:0051607//defense response to virus;GO:0006351//transcription, DNA-templated;GO:0045088//regulation of innate immune response;GO:0006366//transcription from RNA polymerase II promoter;GO:0002819//regulation of adaptive immune response;GO:0006915//apoptotic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0051726//regulation of cell cycle;GO:0045590//negative regulation of regulatory T cell differentiation","K09444//interferon regulatory factor 1","NP_001341853.1//interferon regulatory factor 1 isoform 2 [Homo sapiens];XP_003464582.2//PREDICTED: interferon regulatory factor 1 isoform X2 [Cavia porcellus];NP_001341854.1//interferon regulatory factor 1 isoform 3 [Homo sapiens]","1//3;2//1"]
[8651,1216,0.87,21.4,4.62045158543978,{"v":8.59047047751938e-76,"d":"8.59E-76"},"Up",{"v":6.93734e-78,"d":"6.94E-78"},"SOCS1","GO:0005654//nucleoplasm;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0005737//cytoplasm","GO:0004860//protein kinase inhibitor activity;GO:0005159//insulin-like growth factor receptor binding;GO:0019901//protein kinase binding","GO:0045591//positive regulation of regulatory T cell differentiation;GO:0007259//JAK-STAT cascade;GO:0016567//protein ubiquitination;GO:0046426//negative regulation of JAK-STAT cascade;GO:0042532//negative regulation of tyrosine phosphorylation of STAT protein;GO:0071230//cellular response to amino acid stimulus;GO:0050707//regulation of cytokine secretion;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0006469//negative regulation of protein kinase activity;GO:0010533//regulation of activation of Janus kinase activity;GO:0060334//regulation of interferon-gamma-mediated signaling pathway;GO:0045444//fat cell differentiation;GO:0019221//cytokine-mediated signaling pathway","K04694//suppressor of cytokine signaling 1","XP_019569617.1//PREDICTED: suppressor of cytokine signaling 1 [Rhinolophus sinicus]","1//3"]
[256710,1016,0.01,0.24,4.58496250072116,0.227083932914716,"*",0.1245166,"GLIPR1L1","GO:0045121//membrane raft;GO:0005576//extracellular region;GO:0001669//acrosomal vesicle;GO:0005886//plasma membrane;GO:0031225//anchored component of membrane","NA","GO:0007338//single fertilization","K20412//peptidase inhibitor 16;K19919//cysteine-rich secretory protein","XP_011536436.2//PREDICTED: GLIPR1-like protein 1 isoform X1 [Homo sapiens];NP_001291893.1//GLIPR1-like protein 1 isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[441161,689,0.01,0.24,4.58496250072116,0.395030047222222,"*",0.249274,"OOEP","GO:0005938//cell cortex;GO:0043234//protein complex;GO:0045177//apical part of cell","GO:0003723//RNA binding","GO:0009566//fertilization;GO:0009880//embryonic pattern specification;GO:0006468//protein phosphorylation;GO:0001701//in utero embryonic development;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0007566//embryo implantation;GO:0043623//cellular protein complex assembly","NA","NP_001073976.1//oocyte-expressed protein homolog [Homo sapiens]","2//1"]
[259283,1058,0.01,0.24,4.58496250072116,0.226954377955272,"*",0.1245166,"MDS2","GO:0005615//extracellular space","NA","NA","K09228//KRAB domain-containing zinc finger protein","NP_001335004.1//myelodysplastic syndrome 2 translocation-associated protein [Homo sapiens]","1//3"]
[143678,369,0.01,0.24,4.58496250072116,0.642606785006046,"*",0.499032,"C11orf94","GO:0005576//extracellular region","NA","NA","NA","NP_001073915.2//uncharacterized protein C11orf94 precursor [Homo sapiens]","2//1"]
[51513,1582,0.11,2.54,4.52925306813487,{"v":1.22866683333333e-11,"d":"1.23E-11"},"Up",{"v":1.12606e-12,"d":"1.13E-12"},"ETV7","GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0001227//transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0009887//animal organ morphogenesis;GO:0030154//cell differentiation;GO:0006366//transcription from RNA polymerase II promoter","K03211//ETS translocation variant 6/7","NP_001193968.1//transcription factor ETV7 isoform 6 [Homo sapiens];NP_001193964.1//transcription factor ETV7 isoform 2 [Homo sapiens];NP_001193965.1//transcription factor ETV7 isoform 3 [Homo sapiens];NP_001193966.1//transcription factor ETV7 isoform 4 [Homo sapiens];NP_057219.1//transcription factor ETV7 isoform 1 [Homo sapiens];NP_001193967.1//transcription factor ETV7 isoform 5 [Homo sapiens]","1//3;3//A2MP1"]
[10912,1087,0.01,0.23,4.52356195605701,0.226514994693087,"*",0.1245166,"GADD45G","GO:0005634//nucleus;GO:0005737//cytoplasm","NA","GO:0046330//positive regulation of JNK cascade;GO:1900745//positive regulation of p38MAPK cascade;GO:0043065//positive regulation of apoptotic process;GO:0000185//activation of MAPKKK activity;GO:0030154//cell differentiation;GO:0007275//multicellular organism development;GO:0006950//response to stress;GO:0051726//regulation of cell cycle;GO:0006915//apoptotic process","K04402//growth arrest and DNA-damage-inducible protein","XP_005408930.1//PREDICTED: growth arrest and DNA damage-inducible protein GADD45 gamma [Chinchilla lanigera]","3//A2MP1"]
[3814,731,0.01,0.23,4.52356195605701,0.392073934226073,"*",0.249274,"KISS1","NA","NA","GO:0007186//G-protein coupled receptor signaling pathway;GO:0046697//decidualization","NA","XP_003273200.2//PREDICTED: uncharacterized protein LOC100593139 [Nomascus leucogenys]","3//A2MP1"]
[107080644,1212,0.01,0.22,4.4594316186373,0.226902597353411,"*",0.1245166,"CNPY3-GNMT","GO:0005829//cytosol","GO:0005542//folic acid binding;GO:0017174//glycine N-methyltransferase activity;GO:0016594//glycine binding","GO:0051289//protein homotetramerization;GO:0046500//S-adenosylmethionine metabolic process;GO:0006111//regulation of gluconeogenesis;GO:0006730//one-carbon metabolic process;GO:0005977//glycogen metabolic process;GO:0006555//methionine metabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0006464//cellular protein modification process","K00552//glycine N-methyltransferase [EC:2.1.1.20]","NP_001305785.1//uncharacterized protein LOC107080644 isoform 2 [Homo sapiens];NP_001305786.1//uncharacterized protein LOC107080644 isoform 1 precursor [Homo sapiens];NP_001305787.1//uncharacterized protein LOC107080644 isoform 3 precursor [Homo sapiens]","1//3"]
[642778,1098,0.01,0.22,4.4594316186373,0.394169756087903,"*",0.249274,"NPIPA3","NA","NA","NA","NA","XP_011521050.1//PREDICTED: nuclear pore complex-interacting protein family member A1 isoform X1 [Homo sapiens]","1//3"]
[5047,764,0.01,0.22,4.4594316186373,0.393935781163435,"*",0.249274,"PAEP","GO:0005576//extracellular region","GO:0036094//small molecule binding","GO:0006810//transport;GO:1902491//negative regulation of sperm capacitation;GO:2000667//positive regulation of interleukin-13 secretion;GO:2000359//regulation of binding of sperm to zona pellucida;GO:0006915//apoptotic process;GO:0032725//positive regulation of granulocyte macrophage colony-stimulating factor production;GO:0007275//multicellular organism development;GO:2000778//positive regulation of interleukin-6 secretion","NA","CAB43305.1//hypothetical protein, partial [Homo sapiens]","1//3;3//A2MP1;2//1"]
[9651,5159,0.01,0.22,4.4594316186373,1.27622958468492E-4,"Up",{"v":3.00482e-05,"d":"3.00E-05"},"PLCH2","GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0004435//phosphatidylinositol phospholipase C activity;GO:0005509//calcium ion binding;GO:0004871//signal transducer activity","GO:0016042//lipid catabolic process;GO:0046488//phosphatidylinositol metabolic process;GO:0043647//inositol phosphate metabolic process;GO:0035556//intracellular signal transduction","K19006//phosphatidylinositol phospholipase C, eta [EC:3.1.4.11]","NP_001289941.1//1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 isoform 2 [Homo sapiens];NP_055453.2//1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 isoform 1 [Homo sapiens];XP_016858361.1//PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 isoform X3 [Homo sapiens]","1//3;3//A2MP1"]
[6317,1793,0.01,0.22,4.4594316186373,0.0702666021803766,"*",0.0310688,"SERPINB3","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0031410//cytoplasmic vesicle;GO:0031982//vesicle;GO:0005737//cytoplasm;GO:0035578//azurophil granule lumen;GO:0005576//extracellular region","GO:0002020//protease binding;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0001618//virus receptor activity;GO:0004869//cysteine-type endopeptidase inhibitor activity","GO:0010466//negative regulation of peptidase activity;GO:0030335//positive regulation of cell migration;GO:0045861//negative regulation of proteolysis;GO:0010951//negative regulation of endopeptidase activity;GO:0010950//positive regulation of endopeptidase activity;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0043508//negative regulation of JUN kinase activity;GO:0035425//autocrine signaling;GO:0038001//paracrine signaling;GO:0043086//negative regulation of catalytic activity;GO:0043312//neutrophil degranulation;GO:0008284//positive regulation of cell proliferation","K13963//serpin B","NP_008850.1//serpin B3 [Homo sapiens]","2//1"]
[84366,403,0.01,0.22,4.4594316186373,0.640644311500442,"*",0.499032,"PRAC1","GO:0005634//nucleus","NA","NA","NA","NP_115767.1//small nuclear protein PRAC1 [Homo sapiens]","2//1"]
[2619,2844,0.01,0.22,4.4594316186373,0.0110695703579098,"*",0.00387234,"GAS1","GO:0016021//integral component of membrane;GO:0046658//anchored component of plasma membrane;GO:0005886//plasma membrane","NA","GO:0045165//cell fate commitment;GO:0008589//regulation of smoothened signaling pathway;GO:0045930//negative regulation of mitotic cell cycle;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0007050//cell cycle arrest;GO:0060628//regulation of ER to Golgi vesicle-mediated transport;GO:0010955//negative regulation of protein processing;GO:0048589//developmental growth;GO:0042981//regulation of apoptotic process","K06232//growth arrest-specific 1","XP_019479621.1//PREDICTED: growth arrest-specific protein 1 [Hipposideros armiger]","2//1"]
[219537,1649,0.05,1.08,4.43295940727611,{"v":1.46860112953041E-5,"d":"1.47E-05"},"Up",{"v":2.91716E-6,"d":"2.92E-06"},"SMTNL1","GO:0005634//nucleus;GO:0031430//M band;GO:0031674//I band","GO:0005523//tropomyosin binding;GO:0043621//protein self-association;GO:0097718//disordered domain specific binding;GO:0005516//calmodulin binding;GO:0008157//protein phosphatase 1 binding;GO:0051401//CH domain binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0048644//muscle organ morphogenesis;GO:0042493//response to drug;GO:0045907//positive regulation of vasoconstriction;GO:0018105//peptidyl-serine phosphorylation;GO:0014823//response to activity;GO:0097756//negative regulation of blood vessel diameter","K19538//retinitis pigmentosa 1","NP_001099035.2//smoothelin-like protein 1 [Homo sapiens]","2//1"]
[347549,1898,0.01,0.21,4.39231742277876,0.0702467107147912,"*",0.0310688,"CENPVL3","NA","NA","NA","K06237//collagen, type IV, alpha;K17498//transcription factor SPN1;K16630//collagen, type XXII, alpha;K19720//collagen, type III, alpha","NP_001342205.1//centromere protein V like 3 [Homo sapiens]","1//3"]
[100529257,1856,0.01,0.21,4.39231742277876,0.127541829525032,"*",0.062198,"SYNJ2BP-COX16","GO:0031307//integral component of mitochondrial outer membrane","GO:0008022//protein C-terminus binding","GO:0048312//intracellular distribution of mitochondria","K20057//synaptojanin-2-binding protein","NP_001189477.1//SYNJ2BP-COX16 protein isoform 2 [Homo sapiens];NP_001189476.1//SYNJ2BP-COX16 protein isoform 1 [Homo sapiens];NP_001189478.1//SYNJ2BP-COX16 protein isoform 3 [Homo sapiens]","2//1"]
[135644,2092,0.01,0.21,4.39231742277876,0.0701970312871287,"*",0.0310688,"TRIM40","GO:0005622//intracellular;GO:0008385//IkappaB kinase complex","GO:0008270//zinc ion binding","GO:0030308//negative regulation of cell growth;GO:0045116//protein neddylation;GO:1901223//negative regulation of NIK/NF-kappaB signaling;GO:1900181//negative regulation of protein localization to nucleus;GO:0042177//negative regulation of protein catabolic process;GO:0032088//negative regulation of NF-kappaB transcription factor activity","K12016//tripartite motif-containing protein 40","NP_001273562.1//tripartite motif-containing protein 40 isoform a [Homo sapiens];NP_619645.1//tripartite motif-containing protein 40 isoform b [Homo sapiens]","1//3;4"]
[27290,420,0.01,0.21,4.39231742277876,0.640592829315333,"*",0.499032,"SPINK4","GO:0005576//extracellular region","GO:0004867//serine-type endopeptidase inhibitor activity","GO:0042493//response to drug","NA","NP_055286.1//serine protease inhibitor Kazal-type 4 precursor [Homo sapiens]","2//1"]
[11009,1621,0.01,0.2,4.32192809488736,0.127656540151612,"*",0.062198,"IL24","GO:0005615//extracellular space;GO:0005576//extracellular region","GO:0005125//cytokine activity","GO:0042060//wound healing;GO:0071222//cellular response to lipopolysaccharide;GO:0030336//negative regulation of cell migration;GO:0006915//apoptotic process;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0042501//serine phosphorylation of STAT protein;GO:0071353//cellular response to interleukin-4;GO:0008285//negative regulation of cell proliferation;GO:0008284//positive regulation of cell proliferation","K05444//interleukin 19/20/24","NP_006841.1//interleukin-24 isoform 1 precursor [Homo sapiens];NP_001172086.1//interleukin-24 isoform 4 precursor [Homo sapiens];NP_001172085.1//interleukin-24 isoform 3 precursor [Homo sapiens]","1//3;3//A2MP1"]
[54145,460,0.01,0.2,4.32192809488736,0.647355625142115,"*",0.499032,"H2BFS","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0000786//nucleosome","GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity","GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0021762//substantia nigra development;GO:0006334//nucleosome assembly;GO:0050830//defense response to Gram-positive bacterium;GO:0002227//innate immune response in mucosa;GO:0019731//antibacterial humoral response","K11252//histone H2B","NP_059141.1//histone H2B type F-S [Homo sapiens]","2//1"]
[645073,441,0.01,0.2,4.32192809488736,0.642658591422122,"*",0.499032,"GAGE12G","NA","NA","NA","NA","NP_001468.1//G antigen 12I [Homo sapiens];NP_001341351.1//G antigen 12G isoform 2 [Homo sapiens]","1//3;2//1"]
[51554,2356,0.01,0.2,4.32192809488736,0.0379875721115538,"*",0.0155194,"ACKR4","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0055037//recycling endosome;GO:0005886//plasma membrane;GO:0005769//early endosome","GO:0005044//scavenger receptor activity;GO:0019956//chemokine binding;GO:0004950//chemokine receptor activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0006955//immune response;GO:0006935//chemotaxis","K04186//C-C chemokine receptor-like 1","NP_057641.1//atypical chemokine receptor 4 [Homo sapiens]","3//A2MP1;2//1"]
[3018,431,0.01,0.2,4.32192809488736,0.639770238202247,"*",0.499032,"HIST1H2BB","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000784//nuclear chromosome, telomeric region;GO:0005829//cytosol;GO:0000786//nucleosome","GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity","GO:0016567//protein ubiquitination;GO:0006334//nucleosome assembly","K11252//histone H2B","XP_003502246.1//PREDICTED: histone H2B type 1 isoform X1 [Cricetulus griseus]","2//1"]
[11202,1038,0.01,0.19,4.24792751344359,0.651961819579619,"*",0.499032,"KLK8","GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0004252//serine-type endopeptidase activity","GO:0009611//response to wounding;GO:0048681//negative regulation of axon regeneration;GO:0043616//keratinocyte proliferation;GO:0008219//cell death;GO:0070268//cornification;GO:0007613//memory;GO:0048812//neuron projection morphogenesis;GO:0050808//synapse organization;GO:0031642//negative regulation of myelination;GO:0050807//regulation of synapse organization","K08650//kallikrein 8 [EC:3.4.21.118]","XP_021561667.1//kallikrein-8 isoform X2 [Carlito syrichta];SFW93206.1//TPA: kallikrein H [Homo sapiens];NP_653088.1//kallikrein-8 isoform 2 precursor [Homo sapiens];XP_012365451.1//PREDICTED: kallikrein-8 isoform X3 [Nomascus leucogenys];NP_009127.1//kallikrein-8 isoform 1 preproprotein [Homo sapiens]","1//3;3//A2MP1;2//1"]
[727684,453,0.01,0.19,4.24792751344359,0.6496240867085,"*",0.499032,"C1orf195","NA","NA","NA","NA","NP_001265431.1//putative uncharacterized protein C1orf195 isoform 2 [Homo sapiens];NP_001265430.1//putative uncharacterized protein C1orf195 isoform 1 [Homo sapiens]","1//3"]
[286380,2218,0.01,0.19,4.24792751344359,0.0702566550396376,"*",0.0310688,"FOXD4L3","GO:0005634//nucleus","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0008301//DNA binding, bending","GO:0009653//anatomical structure morphogenesis;GO:0030154//cell differentiation;GO:0006351//transcription, DNA-templated","K09397//forkhead box protein D","AAI03888.1//Forkhead box D4-like 6 [Homo sapiens]",4]
[7356,452,0.01,0.19,4.24792751344359,0.641779016826342,"*",0.499032,"SCGB1A1","GO:0070062//extracellular exosome;GO:0030141//secretory granule;GO:0005615//extracellular space;GO:0005791//rough endoplasmic reticulum;GO:0005635//nuclear envelope;GO:0005737//cytoplasm","GO:0019834//phospholipase A2 inhibitor activity;GO:0097160//polychlorinated biphenyl binding","GO:0032696//negative regulation of interleukin-13 production;GO:0034021//response to silicon dioxide;GO:0034097//response to cytokine;GO:0032496//response to lipopolysaccharide;GO:0010193//response to ozone;GO:0007566//embryo implantation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0042130//negative regulation of T cell proliferation;GO:0043488//regulation of mRNA stability;GO:0051384//response to glucocorticoid;GO:0007565//female pregnancy;GO:0042493//response to drug;GO:0007165//signal transduction;GO:0032713//negative regulation of interleukin-4 production;GO:0009410//response to xenobiotic stimulus;GO:0032714//negative regulation of interleukin-5 production;GO:0050727//regulation of inflammatory response;GO:0071774//response to fibroblast growth factor;GO:0032689//negative regulation of interferon-gamma production","NA","NP_003348.1//uteroglobin precursor [Homo sapiens]",4]
[100526772,1459,0.03,0.54,4.16992500144231,5.91017833894415E-3,"*",1.934294E-3,"TMEM110-MUSTN1","GO:0005634//nucleus;GO:0016021//integral component of membrane","NA","GO:0035988//chondrocyte proliferation;GO:0002062//chondrocyte differentiation;GO:0042246//tissue regeneration","K20179//vacuolar protein sorting-associated protein 11","NP_001185903.2//TMEM110-MUSTN1 fusion protein [Homo sapiens]","2//1"]
[5539,480,0.01,0.18,4.16992500144231,0.654155355982275,"*",0.499032,"PPY","GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0001664//G-protein coupled receptor binding;GO:0005102//receptor binding;GO:0005184//neuropeptide hormone activity;GO:0005179//hormone activity","GO:0009306//protein secretion;GO:0032098//regulation of appetite;GO:0007631//feeding behavior;GO:0007586//digestion;GO:0007267//cell-cell signaling;GO:0007218//neuropeptide signaling pathway","K05234//pancreatic polypeptide","NP_001306138.1//pancreatic prohormone isoform 2 precursor [Homo sapiens];XP_011523280.1//PREDICTED: pancreatic prohormone isoform X1 [Homo sapiens]","1//3;4"]
[1672,484,0.01,0.18,4.16992500144231,0.654101679494543,"*",0.499032,"DEFB1","GO:1990742//microvesicle;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0019898//extrinsic component of membrane;GO:0005576//extracellular region;GO:0097225//sperm midpiece;GO:0005622//intracellular;GO:0005796//Golgi lumen","GO:0042802//identical protein binding;GO:0031731//CCR6 chemokine receptor binding","GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0050829//defense response to Gram-negative bacterium;GO:0042742//defense response to bacterium;GO:0035584//calcium-mediated signaling using intracellular calcium source;GO:0019730//antimicrobial humoral response;GO:0060474//positive regulation of flagellated sperm motility involved in capacitation;GO:0033574//response to testosterone;GO:0006935//chemotaxis;GO:0050830//defense response to Gram-positive bacterium;GO:0045087//innate immune response;GO:0007186//G-protein coupled receptor signaling pathway;GO:0002526//acute inflammatory response;GO:0019933//cAMP-mediated signaling;GO:0006955//immune response;GO:0002227//innate immune response in mucosa;GO:0019731//antibacterial humoral response;GO:0009617//response to bacterium","NA","NP_005209.1//beta-defensin 1 preproprotein [Homo sapiens]","3//A2MP1"]
[8354,477,0.01,0.18,4.16992500144231,0.653029996559351,"*",0.499032,"HIST1H3I","NA","NA","NA","K11253//histone H3","XP_016810252.1//PREDICTED: uncharacterized protein LOC100608783 [Pan troglodytes]","2//1"]
[255426,2216,0.01,0.18,4.16992500144231,0.070296460509915,"*",0.0310688,"RASGEF1C","GO:0005622//intracellular","GO:0005085//guanyl-nucleotide exchange factor activity","GO:0007264//small GTPase mediated signal transduction","K03781//catalase [EC:1.11.1.6];K08018//Rap guanine nucleotide exchange factor 2;K03099//son of sevenless","AAH36802.1//RASGEF1C protein, partial [Homo sapiens]","3//A2MP1"]
[1417,896,0.01,0.18,4.16992500144231,0.393663161245675,"*",0.249274,"CRYBB3","NA","GO:0005212//structural constituent of eye lens","GO:0007601//visual perception","K13596//activin receptor type-2B [EC:2.7.11.30];K16810//TBCC domain-containing protein 1;K01886//glutaminyl-tRNA synthetase [EC:6.1.1.18]","XP_011528204.1//PREDICTED: beta-crystallin B3 isoform X1 [Homo sapiens]",4]
[131540,1370,0.01,0.18,4.16992500144231,0.226386087912588,"*",0.1245166,"ZDHHC19","GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane","GO:0019706//protein-cysteine S-palmitoyltransferase activity","NA","K18932//palmitoyltransferase [EC:2.3.1.225]","NP_001034706.1//probable palmitoyltransferase ZDHHC19 [Homo sapiens]","1//3"]
[85235,481,0.01,0.18,4.16992500144231,0.642969605420229,"*",0.499032,"HIST1H2AH","GO:0005634//nucleus;GO:0000786//nucleosome","GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity","GO:0006334//nucleosome assembly;GO:0006352//DNA-templated transcription, initiation","K11251//histone H2A;K11254//histone H4;K11253//histone H3","XP_019687249.1//PREDICTED: histone H2A type 1-E isoform X2 [Felis catus]","2//1"]
[6355,1351,0.01,0.18,4.16992500144231,0.226154425059693,"*",0.1245166,"CCL8","GO:0005615//extracellular space;GO:0005623//cell","GO:0004672//protein kinase activity;GO:0016004//phospholipase activator activity;GO:0008009//chemokine activity","GO:0006955//immune response;GO:0007267//cell-cell signaling;GO:0006816//calcium ion transport;GO:0006874//cellular calcium ion homeostasis;GO:0006887//exocytosis","K16596//C-C motif chemokine 8","XP_008009204.1//PREDICTED: C-C motif chemokine 8 [Chlorocebus sabaeus]","2//1"]
[3512,1413,0.01,0.17,4.08746284125034,0.226928484700513,"*",0.1245166,"JCHAIN","GO:0071756//pentameric IgM immunoglobulin complex;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0071750//dimeric IgA immunoglobulin complex;GO:0072562//blood microparticle;GO:0071751//secretory IgA immunoglobulin complex;GO:0005576//extracellular region;GO:0071748//monomeric IgA immunoglobulin complex;GO:0071752//secretory dimeric IgA immunoglobulin complex","GO:0034987//immunoglobulin receptor binding;GO:0030674//protein binding, bridging;GO:0019862//IgA binding;GO:0042803//protein homodimerization activity;GO:0003823//antigen binding","GO:0060267//positive regulation of respiratory burst;GO:0003094//glomerular filtration;GO:0050900//leukocyte migration;GO:0001895//retina homeostasis;GO:0002250//adaptive immune response;GO:0032461//positive regulation of protein oligomerization;GO:0006898//receptor-mediated endocytosis;GO:0006955//immune response;GO:0019731//antibacterial humoral response;GO:0045087//innate immune response","NA","XP_007997010.1//PREDICTED: immunoglobulin J chain isoform X1 [Chlorocebus sabaeus]","3//A2MP1"]
[56673,1942,0.01,0.17,4.08746284125034,0.12764014028777,"*",0.062198,"C11orf16","NA","NA","NA","NA","NP_065694.2//uncharacterized protein C11orf16 [Homo sapiens]","2//1"]
[10361,1118,0.01,0.17,4.08746284125034,0.391996739121874,"*",0.249274,"NPM2","NA","NA","NA","K11277//nucleophosmin 2;K11432//histone-lysine N-methyltransferase PRDM2 [EC:2.1.1.43]","XP_016814686.1//PREDICTED: nucleoplasmin-2 isoform X9 [Pan troglodytes];XP_003412535.1//PREDICTED: nucleoplasmin-2 [Loxodonta africana]","1//3"]
[100505724,510,0.01,0.17,4.08746284125034,0.639924313076985,"*",0.499032,"KRTAP9-7","GO:0005829//cytosol;GO:0045095//keratin filament","NA","GO:0031424//keratinization","K17582//antigen KI-67","NP_001264261.1//keratin-associated protein 9-7 [Homo sapiens]","1//3"]
[643246,809,0.01,0.17,4.08746284125034,0.639872946540376,"*",0.499032,"MAP1LC3B2","GO:0016020//membrane;GO:0005874//microtubule;GO:0031090//organelle membrane;GO:0031410//cytoplasmic vesicle;GO:0005622//intracellular;GO:0044754//autolysosome;GO:0012505//endomembrane system;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005776//autophagosome;GO:0005930//axoneme;GO:0000421//autophagosome membrane","GO:0031625//ubiquitin protein ligase binding","GO:0070257//positive regulation of mucus secretion;GO:0009267//cellular response to starvation;GO:0061024//membrane organization;GO:0000422//autophagy of mitochondrion;GO:0097352//autophagosome maturation;GO:0006995//cellular response to nitrogen starvation;GO:0006914//autophagy;GO:0000045//autophagosome assembly;GO:0016236//macroautophagy","K10435//microtubule-associated protein 1 light chain","XP_011536954.1//PREDICTED: microtubule-associated proteins 1A/1B light chain 3 beta 2 isoform X1 [Homo sapiens]","2//1"]
[149643,537,0.01,0.16,4,0.647776464163823,"*",0.499032,"SPATA45","NA","NA","NA","NA","EAW93375.1//hypothetical LOC149643, partial [Homo sapiens]","2//1"]
[84504,1019,0.01,0.16,4,0.392421688775007,"*",0.249274,"NKX6-2","GO:0005634//nucleus","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0010454//negative regulation of cell fate commitment;GO:0045687//positive regulation of glial cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0010455//positive regulation of cell fate commitment;GO:0031018//endocrine pancreas development;GO:0022010//central nervous system myelination;GO:0045686//negative regulation of glial cell differentiation;GO:0021913//regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification;GO:0050885//neuromuscular process controlling balance;GO:0021912//regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification","K09350//homeobox protein Nkx-6.2","NP_796374.1//homeobox protein Nkx-6.2 [Homo sapiens]","2//1"]
[2841,1484,0.01,0.16,4,0.226205864710565,"*",0.1245166,"GPR18","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0030659//cytoplasmic vesicle membrane","GO:0004930//G-protein coupled receptor activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway;GO:0032720//negative regulation of tumor necrosis factor production;GO:0002689//negative regulation of leukocyte chemotaxis;GO:0002300//CD8-positive, alpha-beta intraepithelial T cell differentiation;GO:0035025//positive regulation of Rho protein signal transduction;GO:0002305//CD8-positive, gamma-delta intraepithelial T cell differentiation;GO:0030217//T cell differentiation","K08410//G protein-coupled receptor 18","NP_005283.1//N-arachidonyl glycine receptor [Homo sapiens]","1//3;3//A2MP1"]
[3990,1614,0.01,0.15,3.90689059560852,0.227032093185709,"*",0.1245166,"LIPC","GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0034364//high-density lipoprotein particle;GO:0005576//extracellular region","GO:0004620//phospholipase activity;GO:0030169//low-density lipoprotein particle binding;GO:0004806//triglyceride lipase activity;GO:0008201//heparin binding;GO:0034185//apolipoprotein binding","GO:0019433//triglyceride catabolic process;GO:0008203//cholesterol metabolic process;GO:0034374//low-density lipoprotein particle remodeling;GO:0051004//regulation of lipoprotein lipase activity;GO:0034372//very-low-density lipoprotein particle remodeling;GO:0070328//triglyceride homeostasis;GO:0034375//high-density lipoprotein particle remodeling;GO:0034373//intermediate-density lipoprotein particle remodeling;GO:0034638//phosphatidylcholine catabolic process;GO:0042632//cholesterol homeostasis;GO:0043691//reverse cholesterol transport;GO:0034382//chylomicron remnant clearance;GO:0006633//fatty acid biosynthetic process;GO:0006629//lipid metabolic process","K22283//hepatic triacylglycerol lipase [EC:3.1.1.3]","NP_000227.2//hepatic triacylglycerol lipase precursor [Homo sapiens]","2//1"]
[10406,570,0.01,0.15,3.90689059560852,0.651642047576228,"*",0.499032,"WFDC2","GO:0070062//extracellular exosome;GO:0005615//extracellular space","GO:0004867//serine-type endopeptidase inhibitor activity;GO:0004866//endopeptidase inhibitor activity;GO:0019828//aspartic-type endopeptidase inhibitor activity;GO:0004869//cysteine-type endopeptidase inhibitor activity","GO:0006508//proteolysis;GO:0007283//spermatogenesis","K03910//alpha-2-macroglobulin","NP_006094.3//WAP four-disulfide core domain protein 2 precursor [Homo sapiens]","3//A2MP1"]
[11170,3190,0.01,0.15,3.90689059560852,0.0380166992179114,"*",0.0155194,"FAM107A","GO:0005634//nucleus;GO:0016607//nuclear speck;GO:0043005//neuron projection","NA","GO:0001558//regulation of cell growth","K08405//G protein-coupled receptor 25","XP_007192413.1//PREDICTED: protein FAM107A isoform X1 [Balaenoptera acutorostrata scammoni];BAG51416.1//unnamed protein product [Homo sapiens];XP_007982984.1//PREDICTED: protein FAM107A isoform X1 [Chlorocebus sabaeus];NP_001269643.1//protein FAM107A isoform c [Homo sapiens]","1//3;3//A2MP1;2//1"]
[84616,1099,0.01,0.15,3.90689059560852,0.393896812345435,"*",0.249274,"KRTAP4-4","NA","NA","NA","K00624//carnitine O-acetyltransferase [EC:2.3.1.7];K17582//antigen KI-67","XP_011901963.1//PREDICTED: keratin-associated protein 4-4 isoform X1 [Cercocebus atys]","1//3"]
[388381,566,0.01,0.15,3.90689059560852,0.649200844368434,"*",0.499032,"C17orf98","NA","NA","NA","NA","NP_001073934.1//uncharacterized protein C17orf98 [Homo sapiens]","2//1"]
[1842,3241,0.01,0.15,3.90689059560852,0.0379933939616858,"*",0.0155194,"ECM2","GO:0005615//extracellular space;GO:0005614//interstitial matrix;GO:0005578//proteinaceous extracellular matrix","GO:0070052//collagen V binding;GO:0005178//integrin binding;GO:0008201//heparin binding","GO:0007160//cell-matrix adhesion;GO:0030198//extracellular matrix organization;GO:0010811//positive regulation of cell-substrate adhesion","K08119//extracellular matrix protein 2","NP_001184224.1//extracellular matrix protein 2 isoform 2 precursor [Homo sapiens];NP_001384.1//extracellular matrix protein 2 isoform 1 precursor [Homo sapiens];CAD97940.1//hypothetical protein, partial [Homo sapiens]","1//3;3//A2MP1"]
[7932,1063,0.01,0.15,3.90689059560852,0.393624246342428,"*",0.249274,"OR2H2","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0007608//sensory perception of smell","K04257//olfactory receptor","XP_004043582.1//PREDICTED: olfactory receptor 2H2 [Gorilla gorilla gorilla]","3//A2MP1"]
[100132463,663,0.01,0.15,3.90689059560852,0.646882834374746,"*",0.499032,"CLDN24","GO:0016021//integral component of membrane;GO:0005923//bicellular tight junction;GO:0005886//plasma membrane","GO:0005198//structural molecule activity","NA","K06087//claudin","NP_001172078.1//putative claudin-24 [Homo sapiens]","1//3"]
[100505741,2155,0.01,0.15,3.90689059560852,0.127607353198048,"*",0.062198,"SPATA1","NA","NA","NA","K12478//early endosome antigen 1","NP_001297085.1//spermatogenesis-associated protein 1 [Homo sapiens]","1//3"]
[6359,1073,0.01,0.15,3.90689059560852,0.393196689641552,"*",0.249274,"CCL15","GO:0005615//extracellular space;GO:0005623//cell","GO:0008201//heparin binding;GO:0005102//receptor binding;GO:0008009//chemokine activity;GO:0048020//CCR chemokine receptor binding;GO:0042056//chemoattractant activity","GO:0048247//lymphocyte chemotaxis;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007165//signal transduction;GO:0030593//neutrophil chemotaxis;GO:0070098//chemokine-mediated signaling pathway;GO:0007267//cell-cell signaling;GO:0043547//positive regulation of GTPase activity;GO:0071356//cellular response to tumor necrosis factor;GO:0006954//inflammatory response;GO:0071346//cellular response to interferon-gamma;GO:0071347//cellular response to interleukin-1;GO:0006955//immune response;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0002548//monocyte chemotaxis;GO:0006935//chemotaxis;GO:0006874//cellular calcium ion homeostasis","K05511//C-C motif chemokine 15/23","NP_116741.2//C-C motif chemokine 15 preproprotein [Homo sapiens]",5]
[10871,1602,0.01,0.15,3.90689059560852,0.22641185752988,"*",0.1245166,"CD300C","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004888//transmembrane signaling receptor activity","GO:0002376//immune system process;GO:0006968//cellular defense response;GO:0050776//regulation of immune response","K06719//CD300 antigen","NP_006669.1//CMRF35-like molecule 6 precursor [Homo sapiens]",4]
[100507650,1629,0.01,0.15,3.90689059560852,0.226257327767034,"*",0.1245166,"RNF212B","GO:0000795//synaptonemal complex","GO:0046872//metal ion binding;GO:0019789//SUMO transferase activity","GO:0007129//synapsis;GO:0016925//protein sumoylation","K09379//zinc finger homeobox protein 2;K10330//ankyrin repeat and SOCS box protein 8","NP_001269251.1//RING finger protein 212B [Homo sapiens]","2//1"]
[644591,738,0.01,0.15,3.90689059560852,0.64395647208983,"*",0.499032,"PPIAL4G","GO:0005737//cytoplasm","GO:0003755//peptidyl-prolyl cis-trans isomerase activity","GO:0006457//protein folding","K12738//peptidylprolyl cis-trans isomerase A-like 4 [EC:5.2.1.8]","NP_001116540.1//peptidyl-prolyl cis-trans isomerase A-like 4G [Homo sapiens]","1//3"]
[434,584,0.01,0.15,3.90689059560852,0.6406958019611,"*",0.499032,"ASIP","GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005622//intracellular","GO:0031782//type 4 melanocortin receptor binding;GO:0005102//receptor binding;GO:0031781//type 3 melanocortin receptor binding","GO:0071514//genetic imprinting;GO:0007165//signal transduction;GO:0048023//positive regulation of melanin biosynthetic process;GO:0006091//generation of precursor metabolites and energy;GO:0007267//cell-cell signaling;GO:0042438//melanin biosynthetic process;GO:0032402//melanosome transport;GO:0008343//adult feeding behavior;GO:0009755//hormone-mediated signaling pathway;GO:0040030//regulation of molecular function, epigenetic;GO:0032438//melanosome organization","K08725//agouti signaling protein","XP_005260469.1//PREDICTED: agouti-signaling protein isoform X1 [Homo sapiens]","2//1"]
[26581,594,0.01,0.14,3.8073549220576,0.655823707774578,"*",0.499032,"DUX5","GO:0005634//nucleus","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding","GO:0006355//regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter","K09381//paired box protein 3/7;K09332//retina and anterior neural fold homeobox protein","NP_036281.2//double homeobox protein 5 [Homo sapiens]","2//1"]
[83896,614,0.01,0.14,3.8073549220576,0.653672584501845,"*",0.499032,"KRTAP3-1","GO:0005829//cytosol;GO:0045095//keratin filament","GO:0005198//structural molecule activity","GO:0031424//keratinization","NA","NP_114164.1//keratin-associated protein 3-1 [Homo sapiens]","1//3"]
[440021,1149,0.01,0.14,3.8073549220576,0.395265324200913,"*",0.249274,"KRTAP5-2","GO:0005829//cytosol;GO:0045095//keratin filament","NA","GO:0031424//keratinization","K03006//DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]","BAB70862.1//unnamed protein product [Homo sapiens]","1//3"]
[84221,1185,0.01,0.14,3.8073549220576,0.394990861620871,"*",0.249274,"SPATC1L","GO:0005813//centrosome","NA","NA","K17095//annexin A7/11;K20133//USP6 N-terminal-like protein;K21125//mucin-5AC","NP_001136326.1//speriolin-like protein isoform 1 [Homo sapiens]","4;1//3"]
[8646,3527,0.01,0.14,3.8073549220576,0.0380108702238577,"*",0.0155194,"CHRD","GO:0005615//extracellular space","GO:0019955//cytokine binding;GO:0045545//syndecan binding;GO:0008201//heparin binding","GO:0030514//negative regulation of BMP signaling pathway;GO:0001649//osteoblast differentiation;GO:0001702//gastrulation with mouth forming second;GO:0021919//BMP signaling pathway involved in spinal cord dorsal/ventral patterning;GO:0045785//positive regulation of cell adhesion;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0030336//negative regulation of cell migration;GO:0001707//mesoderm formation;GO:0030900//forebrain development;GO:0007275//multicellular organism development;GO:0045668//negative regulation of osteoblast differentiation;GO:0001501//skeletal system development;GO:0033504//floor plate development","K04657//chordin","XP_016862883.1//PREDICTED: chordin isoform X8 [Homo sapiens];NP_003732.2//chordin isoform 1 precursor [Homo sapiens];NP_001291401.1//chordin isoform 2 precursor [Homo sapiens]","1//3;3//A2MP1"]
[219539,1731,0.01,0.14,3.8073549220576,0.226850840374088,"*",0.1245166,"YPEL4","GO:0005730//nucleolus","GO:0046872//metal ion binding","NA","K14697//solute carrier family 30 (zinc transporter), member 10","XP_003464269.2//PREDICTED: protein yippee-like 4 [Cavia porcellus]","2//1"]
[2981,597,0.01,0.14,3.8073549220576,0.649677030806846,"*",0.499032,"GUCA2B","GO:0070062//extracellular exosome;GO:0005576//extracellular region;GO:0001750//photoreceptor outer segment","GO:0030250//guanylate cyclase activator activity;GO:0008048//calcium sensitive guanylate cyclase activator activity","GO:0045776//negative regulation of blood pressure;GO:0006182//cGMP biosynthetic process;GO:0007589//body fluid secretion;GO:0007586//digestion;GO:0007588//excretion","NA","NP_009033.1//guanylate cyclase activator 2B preproprotein [Homo sapiens]","2//1"]
[1576,2789,0.01,0.14,3.8073549220576,0.0703064189261935,"*",0.0310688,"CYP3A4","GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005737//cytoplasm","GO:0050591//quinine 3-monooxygenase activity;GO:0005506//iron ion binding;GO:0047638//albendazole monooxygenase activity;GO:0019825//oxygen binding;GO:0101020//estrogen 16-alpha-hydroxylase activity;GO:0070576//vitamin D 24-hydroxylase activity;GO:0034875//caffeine oxidase activity;GO:0033780//taurochenodeoxycholate 6alpha-hydroxylase activity;GO:0005496//steroid binding;GO:0016491//oxidoreductase activity;GO:0008395//steroid hydroxylase activity;GO:0020037//heme binding;GO:0070330//aromatase activity;GO:0102320//1,8-cineole 2-exo-monooxygenase activity;GO:0004497//monooxygenase activity;GO:0050649//testosterone 6-beta-hydroxylase activity;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0030343//vitamin D3 25-hydroxylase activity;GO:0019899//enzyme binding","GO:0008209//androgen metabolic process;GO:0070989//oxidative demethylation;GO:0016098//monoterpenoid metabolic process;GO:0006805//xenobiotic metabolic process;GO:0046483//heterocycle metabolic process;GO:0055114//oxidation-reduction process;GO:0017144//drug metabolic process;GO:0008202//steroid metabolic process;GO:0006706//steroid catabolic process;GO:0042738//exogenous drug catabolic process;GO:0042737//drug catabolic process;GO:0042359//vitamin D metabolic process;GO:0009822//alkaloid catabolic process;GO:0002933//lipid hydroxylation;GO:0006629//lipid metabolic process","K17691//cytochrome P450 family 3 subfamily A polypeptide 7 [EC:1.14.14.1];K17689//cytochrome P450 family 3 subfamily A polypeptide 4 [EC:1.14.13.32 1.14.13.67 1.14.13.97 1.14.13.157 1.14.13.-]","NP_001189784.1//cytochrome P450 3A4 isoform 2 [Homo sapiens];XP_002817781.1//PREDICTED: cytochrome P450 3A8 isoform X1 [Pongo abelii]","2//1;5"]
[352999,1201,0.01,0.14,3.8073549220576,0.393468663636364,"*",0.249274,"C6orf58","GO:0070062//extracellular exosome;GO:0005615//extracellular space","NA","GO:0007275//multicellular organism development","NA","NP_001010905.1//protein LEG1 homolog precursor [Homo sapiens]","2//1"]
[94086,616,0.01,0.14,3.8073549220576,0.646935332575881,"*",0.499032,"HSPB9","GO:0005634//nucleus;GO:0005737//cytoplasm","NA","NA","K09547//heat shock protein beta-9","NP_149971.1//heat shock protein beta-9 [Homo sapiens]","2//1"]
[346,622,0.01,0.14,3.8073549220576,0.646672926746167,"*",0.499032,"APOC4","GO:0034364//high-density lipoprotein particle;GO:0034361//very-low-density lipoprotein particle;GO:0005576//extracellular region","GO:0005319//lipid transporter activity","GO:0034379//very-low-density lipoprotein particle assembly;GO:0070328//triglyceride homeostasis;GO:0010890//positive regulation of sequestering of triglyceride;GO:0034447//very-low-density lipoprotein particle clearance;GO:0006629//lipid metabolic process","NA","NP_001637.1//apolipoprotein C-IV precursor [Homo sapiens]","2//1"]
[1474,618,0.01,0.14,3.8073549220576,0.645416336167112,"*",0.499032,"CST6","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0001533//cornified envelope","GO:0002020//protease binding;GO:0004869//cysteine-type endopeptidase inhibitor activity","GO:2000117//negative regulation of cysteine-type endopeptidase activity;GO:0008544//epidermis development;GO:0009653//anatomical structure morphogenesis","K13902//cystatin-M","XP_011820624.1//PREDICTED: cystatin-M [Mandrillus leucophaeus]","3//A2MP1"]
[6690,623,0.01,0.14,3.8073549220576,0.639718896396758,"*",0.499032,"SPINK1","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0001669//acrosomal vesicle","GO:0004867//serine-type endopeptidase inhibitor activity;GO:0004866//endopeptidase inhibitor activity","GO:0060046//regulation of acrosome reaction;GO:0010751//negative regulation of nitric oxide mediated signal transduction;GO:0090281//negative regulation of calcium ion import;GO:2001256//regulation of store-operated calcium entry;GO:1900004//negative regulation of serine-type endopeptidase activity;GO:0050732//negative regulation of peptidyl-tyrosine phosphorylation","K06254//agrin","NP_003113.2//serine protease inhibitor Kazal-type 1 precursor [Homo sapiens]","1//3;4"]
[84210,3511,0.02,0.27,3.75488750216347,0.000872475705482555,"Up",2.41086E-4,"ANKRD20A1","GO:0005886//plasma membrane","NA","NA","K17299//POTE ankyrin domain family protein","NP_115626.2//ankyrin repeat domain-containing protein 20A1 [Homo sapiens]","3//A2MP1"]
[3853,2450,0.1,1.34,3.74416109557041,{"v":6.72951186046512e-09,"d":"6.73E-09"},"Up",{"v":8.3329e-10,"d":"8.33E-10"},"KRT6A","GO:0045095//keratin filament","GO:0005198//structural molecule activity","NA","K07605//type II keratin, basic","AAH69269.1//Keratin 6A [Homo sapiens]","3//A2MP1"]
[347168,969,0.01,0.13,3.70043971814109,0.656039599045346,"*",0.499032,"OR1J1","NA","NA","NA","K04257//olfactory receptor","XP_009455506.2//PREDICTED: LOW QUALITY PROTEIN: olfactory receptor 1J1 [Pan troglodytes]","1//3"]
[132851,1233,0.01,0.13,3.70043971814109,0.395658075914149,"*",0.249274,"SPATA4","GO:0005737//cytoplasm","NA","NA","NA","NP_653245.2//spermatogenesis-associated protein 4 [Homo sapiens]","3//A2MP1"]
[2571,2205,0.01,0.13,3.70043971814109,0.227109861657913,"*",0.1245166,"GAD1","NA","NA","NA","K01580//glutamate decarboxylase [EC:4.1.1.15]","XP_012998052.1//PREDICTED: glutamate decarboxylase 1 isoform X1 [Cavia porcellus];XP_008565872.1//PREDICTED: glutamate decarboxylase 1 isoform X1 [Galeopterus variegatus]","3//A2MP1;2//1"]
[57172,2507,0.01,0.13,3.70043971814109,0.127689352525382,"*",0.062198,"CAMK1G","GO:0012505//endomembrane system;GO:0005954//calcium- and calmodulin-dependent protein kinase complex;GO:0005622//intracellular;GO:0005886//plasma membrane;GO:0043005//neuron projection;GO:0000139//Golgi membrane","GO:0005524//ATP binding;GO:0004683//calmodulin-dependent protein kinase activity;GO:0005516//calmodulin binding","GO:0018107//peptidyl-threonine phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0035556//intracellular signal transduction","K08794//calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]","XP_008954847.1//PREDICTED: calcium/calmodulin-dependent protein kinase type 1G isoform X1 [Pan paniscus]","2//1"]
[26740,942,0.01,0.13,3.70043971814109,0.651109790737564,"*",0.499032,"OR1J2","NA","NA","NA","K04257//olfactory receptor","XP_008697025.1//PREDICTED: olfactory receptor 1J2 [Ursus maritimus]","1//3"]
[6698,668,0.01,0.13,3.70043971814109,0.650897131379113,"*",0.499032,"SPRR1A","GO:0005829//cytosol;GO:0001533//cornified envelope;GO:0005737//cytoplasm","GO:0030280//structural constituent of epidermis;GO:0030674//protein binding, bridging;GO:0005198//structural molecule activity","GO:0018149//peptide cross-linking;GO:0008544//epidermis development;GO:0030216//keratinocyte differentiation;GO:0070268//cornification","K08648//hyaluronan binding protein 2 [EC:3.4.21.-];K06826//nidogen (entactin)","NP_005978.2//cornifin-A [Homo sapiens]","1//3;3//A2MP1"]
[644100,642,0.01,0.13,3.70043971814109,0.649571151238592,"*",0.499032,"ARL14EPL","NA","NA","NA","K08343//ubiquitin-like-conjugating enzyme ATG3;K10366//dystrophin","NP_001182510.1//ARL14 effector protein-like [Homo sapiens]","1//3"]
[391123,1818,0.01,0.13,3.70043971814109,0.226695711009802,"*",0.1245166,"VSIG8","GO:0016021//integral component of membrane","NA","NA","K06788//coxsackievirus and adenovirus receptor","NP_001013683.1//V-set and immunoglobulin domain-containing protein 8 precursor [Homo sapiens]","1//3"]
[440955,662,0.01,0.13,3.70043971814109,0.648936597850863,"*",0.499032,"TMEM89","GO:0005634//nucleus;GO:0016021//integral component of membrane","NA","NA","K10447//kelch-like protein 9/13","NP_001008270.1//transmembrane protein 89 precursor [Homo sapiens]","2//1"]
[11012,1206,0.01,0.13,3.70043971814109,0.393041444674761,"*",0.249274,"KLK11","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005794//Golgi apparatus","GO:0004252//serine-type endopeptidase activity;GO:0008236//serine-type peptidase activity","NA","K09620//kallikrein 11 [EC:3.4.21.-]","XP_011524671.1//PREDICTED: kallikrein-11 isoform X1 [Homo sapiens];NP_659196.1//kallikrein-11 isoform 2 [Homo sapiens]","1//3;2//1"]
[7066,1887,0.01,0.13,3.70043971814109,0.226360324160692,"*",0.1245166,"THPO","GO:0005615//extracellular space","GO:0008083//growth factor activity;GO:0005125//cytokine activity;GO:0005179//hormone activity","GO:0051897//positive regulation of protein kinase B signaling;GO:0030099//myeloid cell differentiation;GO:0045654//positive regulation of megakaryocyte differentiation;GO:0038163//thrombopoietin-mediated signaling pathway;GO:1902035//positive regulation of hematopoietic stem cell proliferation;GO:0008283//cell proliferation;GO:0007275//multicellular organism development;GO:0001934//positive regulation of protein phosphorylation;GO:0070374//positive regulation of ERK1 and ERK2 cascade","K06854//thrombopoietin","XP_016797915.1//PREDICTED: thrombopoietin isoform X2 [Pan troglodytes];EAW78244.1//thrombopoietin (myeloproliferative leukemia virus oncogene ligand, megakaryocyte growth and development factor), isoform CRA_b [Homo sapiens];XP_003806645.3//PREDICTED: thrombopoietin isoform X1 [Pan paniscus];XP_008953683.2//PREDICTED: thrombopoietin isoform X2 [Pan paniscus];XP_008953684.2//PREDICTED: thrombopoietin isoform X3 [Pan paniscus];NP_001276932.1//thrombopoietin isoform 5 [Homo sapiens];XP_016797919.1//PREDICTED: thrombopoietin isoform X5 [Pan troglodytes]","1//3;3//A2MP1;2//1"]
[341346,1272,0.01,0.13,3.70043971814109,0.392770060761491,"*",0.249274,"SMCO2","GO:0016021//integral component of membrane","NA","NA","NA","NP_001138482.1//single-pass membrane and coiled-coil domain-containing protein 2 [Homo sapiens]","1//3"]
[3596,1272,0.01,0.13,3.70043971814109,0.392344356685388,"*",0.249274,"IL13","GO:0005615//extracellular space;GO:0009897//external side of plasma membrane;GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0005125//cytokine activity;GO:0005144//interleukin-13 receptor binding","GO:1901215//negative regulation of neuron death;GO:0035094//response to nicotine;GO:0071260//cellular response to mechanical stimulus;GO:0032496//response to lipopolysaccharide;GO:0002639//positive regulation of immunoglobulin production;GO:0045471//response to ethanol;GO:0030890//positive regulation of B cell proliferation;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0071345//cellular response to cytokine stimulus;GO:0001774//microglial cell activation;GO:1901251//positive regulation of lung goblet cell differentiation;GO:0010155//regulation of proton transport;GO:1903660//negative regulation of complement-dependent cytotoxicity;GO:0033861//negative regulation of NAD(P)H oxidase activity;GO:0007165//signal transduction;GO:0043032//positive regulation of macrophage activation;GO:0043306//positive regulation of mast cell degranulation;GO:0007267//cell-cell signaling;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:0006954//inflammatory response;GO:1901247//negative regulation of lung ciliated cell differentiation;GO:0050714//positive regulation of protein secretion;GO:0071635//negative regulation of transforming growth factor beta production;GO:0006928//movement of cell or subcellular component;GO:0032723//positive regulation of connective tissue growth factor production;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0006955//immune response;GO:2000231//positive regulation of pancreatic stellate cell proliferation","K05435//interleukin 13","XP_016800435.1//PREDICTED: interleukin-13 isoform X1 [Pan troglodytes];XP_016809256.1//PREDICTED: interleukin-13 isoform X1 [Pan troglodytes];AAH96141.2//Interleukin 13 [Homo sapiens]","1//3;2//1"]
[6699,641,0.01,0.13,3.70043971814109,0.642140902851619,"*",0.499032,"SPRR1B","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0001533//cornified envelope;GO:0005737//cytoplasm","GO:0030674//protein binding, bridging;GO:0005198//structural molecule activity","GO:0018149//peptide cross-linking;GO:0008544//epidermis development;GO:0030216//keratinocyte differentiation;GO:0070268//cornification","K17602//YLP motif-containing protein 1;K02133//F-type H+-transporting ATPase subunit beta [EC:3.6.3.14]","NP_003116.2//cornifin-B [Homo sapiens]","2//1"]
[3822,1223,0.01,0.13,3.70043971814109,0.391919574409449,"*",0.249274,"KLRC2","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0043235//receptor complex","GO:0030246//carbohydrate binding;GO:1990405//protein antigen binding;GO:0004888//transmembrane signaling receptor activity;GO:0023024//MHC class I protein complex binding","GO:0002228//natural killer cell mediated immunity;GO:0007165//signal transduction;GO:0045087//innate immune response;GO:0006968//cellular defense response","K06541//killer cell lectin-like receptor subfamily C","NP_002251.2//NKG2-C type II integral membrane protein [Homo sapiens]","3//A2MP1"]
[922,1736,0.01,0.13,3.70043971814109,0.391881003444543,"*",0.249274,"CD5L","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0072562//blood microparticle;GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0005044//scavenger receptor activity","GO:0002376//immune system process;GO:0006968//cellular defense response;GO:0006954//inflammatory response;GO:0006915//apoptotic process","K13912//deleted in malignant brain tumors 1 protein","NP_005885.1//CD5 antigen-like isoform 1 precursor [Homo sapiens];NP_001334627.1//CD5 antigen-like isoform 2 precursor [Homo sapiens]","1//3;2//1"]
[344805,2509,0.01,0.13,3.70043971814109,0.127525459119497,"*",0.062198,"TMPRSS7","NA","NA","NA","K09638//transmembrane protease serine 7 [EC:3.4.21.-]","XP_009444420.2//PREDICTED: transmembrane protease serine 7 isoform X1 [Pan troglodytes]","2//1"]
[123346,1210,0.01,0.13,3.70043971814109,0.639205931200385,"*",0.499032,"HIGD2B","GO:0016021//integral component of membrane;GO:0005739//mitochondrion","NA","GO:0097250//mitochondrial respiratory chain supercomplex assembly","K18402//PHD finger protein 20;K09291//nucleoprotein TPR","XP_009248269.1//PREDICTED: LOW QUALITY PROTEIN: putative HIG1 domain family member 2B [Pongo abelii]","1//3"]
[8519,733,0.15,1.92,3.67807190511264,0.000538049712249233,"Up",0.0001427142,"IFITM1","GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005057//signal transducer activity, downstream of receptor","GO:0035456//response to interferon-beta;GO:0060337//type I interferon signaling pathway;GO:0051607//defense response to virus;GO:0046597//negative regulation of viral entry into host cell;GO:0030336//negative regulation of cell migration;GO:0007166//cell surface receptor signaling pathway;GO:0045669//positive regulation of osteoblast differentiation;GO:0001503//ossification;GO:0035455//response to interferon-alpha;GO:0034341//response to interferon-gamma;GO:0045071//negative regulation of viral genome replication;GO:0009615//response to virus;GO:0009607//response to biotic stimulus;GO:0050776//regulation of immune response;GO:0008285//negative regulation of cell proliferation","K19831//interferon induced transmembrane protein 1","NP_003632.3//interferon-induced transmembrane protein 1 [Homo sapiens]","3//A2MP1"]
[84225,2424,0.07,0.89,3.66837850890879,{"v":4.59503892318151e-06,"d":"4.60E-06"},"Up",{"v":8.46288e-07,"d":"8.46E-07"},"ZMYND15","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0042826//histone deacetylase binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0007286//spermatid development","K03006//DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6];K10518//zinc finger and BTB domain-containing protein 47","XP_003315366.2//PREDICTED: zinc finger MYND domain-containing protein 15 isoform X1 [Pan troglodytes];NP_115641.1//zinc finger MYND domain-containing protein 15 isoform 2 [Homo sapiens]","1//3;2//1"]
[145864,2025,5.87,72.96,3.63567332105469,0,"Up",0,"HAPLN3","GO:0005615//extracellular space;GO:0005578//proteinaceous extracellular matrix","GO:0005201//extracellular matrix structural constituent;GO:0005540//hyaluronic acid binding","GO:0007155//cell adhesion;GO:0001501//skeletal system development;GO:0007417//central nervous system development","K06852//hyaluronan and proteoglycan link protein 3","XP_011519563.1//PREDICTED: hyaluronan and proteoglycan link protein 3 isoform X1 [Homo sapiens];NP_001294881.1//hyaluronan and proteoglycan link protein 3 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[389493,682,0.01,0.12,3.58496250072116,0.6540480118149,"*",0.499032,"NUPR2","NA","NA","NA","K09291//nucleoprotein TPR","XP_003896002.2//nuclear protein 2 [Papio anubis]","1//3"]
[972,1322,0.01,0.12,3.58496250072116,0.39522609191067,"*",0.249274,"CD74","GO:0005783//endoplasmic reticulum;GO:0009897//external side of plasma membrane;GO:0030666//endocytic vesicle membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome;GO:0042613//MHC class II protein complex;GO:0005622//intracellular;GO:0005764//lysosome;GO:0005773//vacuole;GO:0009986//cell surface;GO:0035692//macrophage migration inhibitory factor receptor complex;GO:0035693//NOS2-CD74 complex;GO:0005794//Golgi apparatus;GO:0005771//multivesicular body;GO:0012507//ER to Golgi transport vesicle membrane","GO:0035718//macrophage migration inhibitory factor binding;GO:0019955//cytokine binding;GO:0001540//amyloid-beta binding;GO:0004896//cytokine receptor activity;GO:0042658//MHC class II protein binding, via antigen binding groove;GO:0042609//CD4 receptor binding;GO:0042289//MHC class II protein binding;GO:0050998//nitric-oxide synthase binding;GO:0044183//protein binding involved in protein folding","GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0016064//immunoglobulin mediated immune response;GO:0002606//positive regulation of dendritic cell antigen processing and presentation;GO:0045060//negative thymic T cell selection;GO:0030890//positive regulation of B cell proliferation;GO:0045581//negative regulation of T cell differentiation;GO:0001516//prostaglandin biosynthetic process;GO:0002906//negative regulation of mature B cell apoptotic process;GO:0019883//antigen processing and presentation of endogenous antigen;GO:0048146//positive regulation of fibroblast proliferation;GO:0051290//protein heterotetramerization;GO:0046598//positive regulation of viral entry into host cell;GO:0006886//intracellular protein transport;GO:1902166//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0033674//positive regulation of kinase activity;GO:0070206//protein trimerization;GO:0051085//chaperone cofactor-dependent protein refolding;GO:0045893//positive regulation of transcription, DNA-templated;GO:0001961//positive regulation of cytokine-mediated signaling pathway;GO:0043518//negative regulation of DNA damage response, signal transduction by p53 class mediator;GO:0008283//cell proliferation;GO:0045582//positive regulation of T cell differentiation;GO:0060907//positive regulation of macrophage cytokine production;GO:0002792//negative regulation of peptide secretion;GO:0019882//antigen processing and presentation;GO:0000187//activation of MAPK activity;GO:0090023//positive regulation of neutrophil chemotaxis;GO:0035691//macrophage migration inhibitory factor signaling pathway;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0006952//defense response;GO:0002830//positive regulation of type 2 immune response;GO:0006955//immune response;GO:0045657//positive regulation of monocyte differentiation;GO:0045059//positive thymic T cell selection;GO:2000343//positive regulation of chemokine (C-X-C motif) ligand 2 production;GO:0070374//positive regulation of ERK1 and ERK2 cascade","K06505//CD74 antigen","NP_001020329.1//HLA class II histocompatibility antigen gamma chain isoform c [Homo sapiens];NP_004346.1//HLA class II histocompatibility antigen gamma chain isoform b [Homo sapiens];NP_001020330.1//HLA class II histocompatibility antigen gamma chain isoform a [Homo sapiens]","3//A2MP1;2//1"]
[9737,5826,0.01,0.12,3.58496250072116,0.0295116791601718,"*",0.01161512,"GPRASP1","GO:0005829//cytosol","NA","GO:1990172//G-protein coupled receptor catabolic process;GO:0008333//endosome to lysosome transport","K22016//mucin-3/17","NP_055525.3//G-protein coupled receptor-associated sorting protein 1 [Homo sapiens]","4;1//3"]
[165545,2650,0.01,0.12,3.58496250072116,0.12770576503856,"*",0.062198,"DQX1","GO:0005681//spliceosomal complex;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0004004//ATP-dependent RNA helicase activity;GO:0005524//ATP binding","GO:0000398//mRNA splicing, via spliceosome","K14433//ATP-dependent RNA helicase DQX1 [EC:3.6.4.13]","XP_009440984.1//PREDICTED: ATP-dependent RNA helicase DQX1 [Pan troglodytes]","2//1"]
[5653,1486,0.01,0.12,3.58496250072116,0.392576444444444,"*",0.249274,"KLK6","GO:0030141//secretory granule;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005730//nucleolus;GO:0005576//extracellular region;GO:0005739//mitochondrion;GO:0005737//cytoplasm","GO:0004252//serine-type endopeptidase activity","GO:0009611//response to wounding;GO:0042552//myelination;GO:0016540//protein autoprocessing;GO:0042445//hormone metabolic process;GO:0070997//neuron death;GO:0042246//tissue regeneration;GO:0007417//central nervous system development;GO:0045745//positive regulation of G-protein coupled receptor protein signaling pathway;GO:0042982//amyloid precursor protein metabolic process;GO:0010975//regulation of neuron projection development;GO:0045595//regulation of cell differentiation;GO:0030574//collagen catabolic process","K08667//kallikrein 6 [EC:3.4.21.-]","SFW93207.1//TPA: kallikrein I [Homo sapiens];XP_011801672.1//PREDICTED: kallikrein-6 isoform X1 [Colobus angolensis palliatus];XP_010367876.1//PREDICTED: kallikrein-6 isoform X2 [Rhinopithecus roxellana]","1//3;3//A2MP1;2//1"]
[114769,726,0.01,0.12,3.58496250072116,0.642451415860735,"*",0.499032,"CARD16","GO:0097179//protease inhibitor complex;GO:0043234//protein complex","GO:0089720//caspase binding;GO:0050700//CARD domain binding;GO:0042802//identical protein binding;GO:0019900//kinase binding;GO:0004869//cysteine-type endopeptidase inhibitor activity","GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0071456//cellular response to hypoxia;GO:0010804//negative regulation of tumor necrosis factor-mediated signaling pathway;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0031665//negative regulation of lipopolysaccharide-mediated signaling pathway;GO:0050713//negative regulation of interleukin-1 beta secretion;GO:0071222//cellular response to lipopolysaccharide;GO:0071494//cellular response to UV-C;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0032091//negative regulation of protein binding;GO:0097340//inhibition of cysteine-type endopeptidase activity","K12806//caspase recruitment domain-containing protein 16/17/18;K01370//caspase 1 [EC:3.4.22.36]","NP_001017534.1//caspase recruitment domain-containing protein 16 isoform 1 [Homo sapiens]","1//3;2//1"]
[399949,719,0.01,0.12,3.58496250072116,0.641159588836162,"*",0.499032,"C11orf88","NA","NA","NA","K10077//layilin","NP_997313.2//UPF0722 protein C11orf88 isoform 1 [Homo sapiens];NP_001093858.1//UPF0722 protein C11orf88 isoform 2 [Homo sapiens]","1//3;2//1"]
[133060,1946,0.01,0.12,3.58496250072116,0.226077309433962,"*",0.1245166,"OTOP1","GO:0005615//extracellular space;GO:0016021//integral component of membrane","NA","GO:0031214//biomineral tissue development","K21882//PDZ domain-containing protein 7","NP_819056.1//otopetrin-1 [Homo sapiens]","2//1"]
[8637,728,0.51,5.76,3.49749965947082,{"v":3.42318019328226e-10,"d":"3.42E-10"},"Up",{"v":3.63662e-11,"d":"3.64E-11"},"EIF4EBP3","GO:0016020//membrane;GO:0005737//cytoplasm;GO:0016281//eukaryotic translation initiation factor 4F complex","GO:0008190//eukaryotic initiation factor 4E binding;GO:0003743//translation initiation factor activity;GO:0030371//translation repressor activity","GO:0045947//negative regulation of translational initiation","K18645//eukaryotic translation initiation factor 4E binding protein 3","XP_019595811.1//PREDICTED: eukaryotic translation initiation factor 4E-binding protein 3 [Rhinolophus sinicus]","2//1"]
[181,783,0.01,0.11,3.4594316186373,0.655500137159773,"*",0.499032,"AGRP","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0043025//neuronal cell body;GO:0005796//Golgi lumen","GO:0005102//receptor binding;GO:0005184//neuropeptide hormone activity","GO:0007623//circadian rhythm;GO:0060135//maternal process involved in female pregnancy;GO:0032868//response to insulin;GO:0042755//eating behavior;GO:0060259//regulation of feeding behavior;GO:2000253//positive regulation of feeding behavior;GO:0008343//adult feeding behavior;GO:0007631//feeding behavior;GO:0048571//long-day photoperiodism;GO:0007218//neuropeptide signaling pathway;GO:0009755//hormone-mediated signaling pathway","K05231//agouti related protein","NP_001129.1//agouti-related protein precursor [Homo sapiens]","1//3"]
[1071,1537,0.01,0.11,3.4594316186373,0.395304564280751,"*",0.249274,"CETP","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0034364//high-density lipoprotein particle;GO:0005576//extracellular region;GO:0031982//vesicle","GO:0005319//lipid transporter activity;GO:0008289//lipid binding;GO:0031210//phosphatidylcholine binding;GO:0015485//cholesterol binding;GO:0017129//triglyceride binding;GO:0017127//cholesterol transporter activity;GO:0005548//phospholipid transporter activity","GO:0046470//phosphatidylcholine metabolic process;GO:0008203//cholesterol metabolic process;GO:0006869//lipid transport;GO:0034374//low-density lipoprotein particle remodeling;GO:0030301//cholesterol transport;GO:0034372//very-low-density lipoprotein particle remodeling;GO:0070328//triglyceride homeostasis;GO:0015914//phospholipid transport;GO:0042632//cholesterol homeostasis;GO:0055091//phospholipid homeostasis;GO:0010874//regulation of cholesterol efflux;GO:0006641//triglyceride metabolic process;GO:0034197//triglyceride transport;GO:0010745//negative regulation of macrophage derived foam cell differentiation;GO:0034375//high-density lipoprotein particle remodeling;GO:0055088//lipid homeostasis;GO:0043691//reverse cholesterol transport","K16835//cholesteryl ester transfer protein","NP_000069.2//cholesteryl ester transfer protein isoform 1 precursor [Homo sapiens];NP_001273014.1//cholesteryl ester transfer protein isoform 2 precursor [Homo sapiens]","1//3;2//1"]
[3009,790,0.01,0.11,3.4594316186373,0.652869546928747,"*",0.499032,"HIST1H1B","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0000786//nucleosome;GO:0005720//nuclear heterochromatin","GO:0003723//RNA binding;GO:0042826//histone deacetylase binding;GO:0031490//chromatin DNA binding","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006325//chromatin organization;GO:0006334//nucleosome assembly;GO:0030307//positive regulation of cell growth;GO:0050821//protein stabilization;GO:0051574//positive regulation of histone H3-K9 methylation;GO:0071169//establishment of protein localization to chromatin","K11275//histone H1/5","XP_011931511.1//PREDICTED: uncharacterized protein LOC105593202 [Cercocebus atys]","2//1"]
[100653515,2167,0.01,0.11,3.4594316186373,0.227006182195846,"*",0.1245166,"CEP295NL","GO:0031514//motile cilium","NA","NA","K18626//trichohyalin;K13172//serine/arginine repetitive matrix protein 2;K10388//plectin","NP_001230469.1//protein DDC8 homolog isoform 2 [Homo sapiens]","1//3"]
[1504,748,0.01,0.11,3.4594316186373,0.650684610888907,"*",0.499032,"CTRB1","GO:0005615//extracellular space;GO:0005576//extracellular region","GO:0004252//serine-type endopeptidase activity;GO:0008236//serine-type peptidase activity","GO:0022617//extracellular matrix disassembly;GO:0007586//digestion;GO:0009235//cobalamin metabolic process","K01310//chymotrypsin [EC:3.4.21.1]","NP_001897.4//chymotrypsinogen B isoform 1 precursor [Homo sapiens];NP_001316119.1//chymotrypsinogen B isoform 2 precursor [Homo sapiens]","1//3;5"]
[266675,2096,0.01,0.11,3.4594316186373,0.226592409250399,"*",0.1245166,"BEST4","GO:0034707//chloride channel complex;GO:0005886//plasma membrane","GO:0005254//chloride channel activity","NA","K13881//bestrophin-4","XP_021796530.1//bestrophin-4 isoform X1 [Papio anubis]","2//1"]
[5672,1829,0.01,0.11,3.4594316186373,0.226463414368667,"*",0.1245166,"PSG4","GO:0070062//extracellular exosome","NA","GO:0007565//female pregnancy","K06500//pregnancy specific beta-1-glycoprotein","NP_001263424.1//pregnancy-specific beta-1-glycoprotein 4 isoform 3 precursor [Homo sapiens];NP_001303268.1//pregnancy-specific beta-1-glycoprotein 4 isoform 4 [Homo sapiens];NP_002771.2//pregnancy-specific beta-1-glycoprotein 4 isoform 1 precursor [Homo sapiens];XP_009230948.1//PREDICTED: pregnancy-specific beta-1-glycoprotein 2-like isoform X2 [Pongo abelii]","1//3;4;2//1"]
[29986,1413,0.01,0.11,3.4594316186373,0.393119051831375,"*",0.249274,"SLC39A2","GO:0005887//integral component of plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005385//zinc ion transmembrane transporter activity","GO:0006829//zinc II ion transport;GO:0071577//zinc II ion transmembrane transport","K14709//solute carrier family 39 (zinc transporter), member 1/2/3","NP_055394.2//zinc transporter ZIP2 isoform a [Homo sapiens]","1//3;3//A2MP1"]
[56660,1449,0.01,0.11,3.4594316186373,0.393002652585867,"*",0.249274,"KCNK12","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane","GO:0005244//voltage-gated ion channel activity;GO:0005267//potassium channel activity;GO:0022841//potassium ion leak channel activity","GO:0030322//stabilization of membrane potential;GO:0071805//potassium ion transmembrane transport","K04921//potassium channel subfamily K member 12","NP_071338.1//potassium channel subfamily K member 12 [Homo sapiens]","1//3"]
[389812,762,0.01,0.11,3.4594316186373,0.645939321610891,"*",0.499032,"LCN15","GO:0005576//extracellular region","GO:0005215//transporter activity;GO:0036094//small molecule binding","GO:0006629//lipid metabolic process","K01830//prostaglandin-H2 D-isomerase [EC:5.3.99.2]","NP_976222.1//lipocalin-15 precursor [Homo sapiens]","1//3"]
[89886,761,0.01,0.11,3.4594316186373,0.645259605633803,"*",0.499032,"SLAMF9","GO:0016021//integral component of membrane","NA","NA","K06570//lymphocyte antigen 9;K06511//CD84 antigen","NP_001139645.1//SLAM family member 9 isoform 3 precursor [Homo sapiens];NP_001139644.1//SLAM family member 9 isoform 2 precursor [Homo sapiens];NP_254273.2//SLAM family member 9 isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[3007,777,0.01,0.11,3.4594316186373,0.643021470355731,"*",0.499032,"HIST1H1D","GO:0005719//nuclear euchromatin;GO:0000790//nuclear chromatin;GO:0000786//nucleosome","GO:0003723//RNA binding;GO:0031490//chromatin DNA binding","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0098532//histone H3-K27 trimethylation;GO:0006334//nucleosome assembly;GO:0080182//histone H3-K4 trimethylation;GO:0016584//nucleosome positioning","K11275//histone H1/5","NP_005311.1//histone H1.3 [Homo sapiens]","2//1"]
[6866,787,0.01,0.11,3.4594316186373,0.641934060879369,"*",0.499032,"TAC3","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005576//extracellular region","GO:0031837//substance K receptor binding;GO:0031836//neuromedin K receptor binding;GO:0005102//receptor binding","GO:0007565//female pregnancy;GO:0007217//tachykinin receptor signaling pathway;GO:1902093//positive regulation of flagellated sperm motility;GO:0007218//neuropeptide signaling pathway","K05240//tachykinin 2/3","NP_037383.1//tachykinin-3 isoform 1 preproprotein [Homo sapiens];NP_001171525.1//tachykinin-3 isoform 2 precursor [Homo sapiens]","1//3;3//A2MP1"]
[79413,2226,0.01,0.11,3.4594316186373,0.226103008798454,"*",0.1245166,"ZBED2","NA","GO:0046872//metal ion binding;GO:0003677//DNA binding","NA","K06517//CD96 antigen","NP_078784.2//zinc finger BED domain-containing protein 2 [Homo sapiens]",4]
[405753,1451,0.01,0.11,3.4594316186373,0.391958152967812,"*",0.249274,"DUOXA2","GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","NA","GO:0050727//regulation of inflammatory response;GO:2000609//regulation of thyroid hormone generation;GO:0042743//hydrogen peroxide metabolic process;GO:0015031//protein transport","K17232//dual oxidase maturation factor 2","NP_997464.2//dual oxidase maturation factor 2 [Homo sapiens]","3//A2MP1"]
[6890,2656,8.92,96.68,3.43810185784528,0,"Up",0,"TAP1","GO:0005815//microtubule organizing center;GO:0042825//TAP complex;GO:0005739//mitochondrion","GO:0043531//ADP binding;GO:0015440//peptide-transporting ATPase activity;GO:0005524//ATP binding;GO:0046979//TAP2 binding;GO:0023029//MHC class Ib protein binding;GO:0042288//MHC class I protein binding","GO:0046967//cytosol to ER transport;GO:0006952//defense response;GO:0019885//antigen processing and presentation of endogenous peptide antigen via MHC class I","K05653//ATP-binding cassette, subfamily B (MDR/TAP), member 2","XP_012358659.1//PREDICTED: antigen peptide transporter 1 isoform X2 [Nomascus leucogenys];BAG36500.1//unnamed protein product [Homo sapiens]","1//3;5"]
[5698,1048,2.82,29.55,3.3893910626661,{"v":3.88023187801418e-71,"d":"3.88E-71"},"Up",{"v":3.42502e-73,"d":"3.43E-73"},"PSMB9","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000502//proteasome complex;GO:1990111//spermatoproteasome complex;GO:0005737//cytoplasm;GO:0005839//proteasome core complex;GO:0005829//cytosol;GO:0019774//proteasome core complex, beta-subunit complex","GO:0004298//threonine-type endopeptidase activity","GO:0043687//post-translational protein modification;GO:0038061//NIK/NF-kappaB signaling;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0006521//regulation of cellular amino acid metabolic process;GO:2000116//regulation of cysteine-type endopeptidase activity;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0016579//protein deubiquitination;GO:0043488//regulation of mRNA stability;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0000209//protein polyubiquitination;GO:0055085//transmembrane transport;GO:0000165//MAPK cascade;GO:0050852//T cell receptor signaling pathway;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0016032//viral process;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:1902036//regulation of hematopoietic stem cell differentiation","K02741//20S proteasome subunit beta 9 [EC:3.4.25.1]","NP_002791.1//proteasome subunit beta type-9 precursor [Homo sapiens]",4]
[23764,2269,3.8,39.79,3.38833457536279,{"v":5.10230491448276e-214,"d":"5.10E-214"},"Up",{"v":9.26297999999999e-217,"d":"9.26E-217"},"MAFF","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion","GO:0003677//DNA binding;GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0007596//blood coagulation;GO:0006351//transcription, DNA-templated;GO:0001701//in utero embryonic development;GO:0006366//transcription from RNA polymerase II promoter;GO:0035914//skeletal muscle cell differentiation;GO:0007567//parturition;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045604//regulation of epidermal cell differentiation","K09037//transcription factor MAFF/G/K","NP_036455.1//transcription factor MafF isoform a [Homo sapiens];XP_011834265.1//PREDICTED: transcription factor MafF isoform X1 [Mandrillus leucophaeus];XP_011819623.1//PREDICTED: transcription factor MafF isoform X1 [Colobus angolensis palliatus]","1//3;3//A2MP1"]
[29802,602,0.14,1.42,3.34239219744708,0.0170814726913916,"*",0.00628552,"VPREB3","GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005576//extracellular region","NA","GO:0050900//leukocyte migration;GO:0002377//immunoglobulin production;GO:0006955//immune response","K06553//pre-B lymphocyte gene","NP_037510.1//pre-B lymphocyte protein 3 precursor [Homo sapiens]","2//1"]
[554235,865,0.01,0.1,3.32192809488736,0.65576975715696,"*",0.499032,"ASPDH","NA","GO:0050661//NADP binding;GO:0033735//aspartate dehydrogenase activity","GO:0006742//NADP catabolic process;GO:0009435//NAD biosynthetic process","K16360//netrin-G3 ligand;K15235//josephin [EC:3.4.19.12]","XP_524347.3//PREDICTED: putative L-aspartate dehydrogenase isoform X1 [Pan troglodytes];NP_001019827.2//putative L-aspartate dehydrogenase isoform 2 [Homo sapiens]","1//3;2//1"]
[4102,1753,0.01,0.1,3.32192809488736,0.394560332540626,"*",0.249274,"MAGEA3","GO:0005783//endoplasmic reticulum","GO:0089720//caspase binding","GO:0010955//negative regulation of protein processing;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:1902236//negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway","K12464//melanoma-associated antigen D1","NP_005353.1//melanoma-associated antigen 3 [Homo sapiens]","3//A2MP1"]
[132946,836,0.01,0.1,3.32192809488736,0.651216172534924,"*",0.499032,"ARL9","NA","NA","NA","K07957//ADP-ribosylation factor-like protein 9","Q6T311.1//RecName: Full=ADP-ribosylation factor-like protein 9","1//3"]
[388125,1576,0.01,0.1,3.32192809488736,0.394482155339806,"*",0.249274,"C2CD4B","GO:0005634//nucleus;GO:0005886//plasma membrane","GO:0005544//calcium-dependent phospholipid binding;GO:0005509//calcium ion binding","NA","K16628//collagen, type VII, alpha","NP_001007596.2//C2 calcium-dependent domain-containing protein 4B [Homo sapiens]","2//1"]
[388551,1692,0.01,0.1,3.32192809488736,0.39440400911252,"*",0.249274,"CEACAM16","GO:0005615//extracellular space;GO:0032426//stereocilium tip","GO:0042802//identical protein binding","GO:0007605//sensory perception of sound","K06499//carcinoembryonic antigen-related cell adhesion molecule","AAQ05841.1//carcinoembryonic antigen like-2 protein [Homo sapiens]","3//A2MP1"]
[148545,2499,0.01,0.1,3.32192809488736,0.22679910700114,"*",0.1245166,"NBPF4","GO:0005737//cytoplasm","NA","NA","K22244//regenerating islet-derived protein 4;K16549//myomegalin","XP_005271201.1//PREDICTED: neuroblastoma breakpoint family member 6 isoform X1 [Homo sapiens]","2//1"]
[3046,816,0.01,0.1,3.32192809488736,0.650153916320039,"*",0.499032,"HBE1","GO:0072562//blood microparticle;GO:0005829//cytosol;GO:0005833//hemoglobin complex","GO:0020037//heme binding;GO:0005506//iron ion binding;GO:0005344//oxygen carrier activity;GO:0019825//oxygen binding;GO:0031721//hemoglobin alpha binding","GO:0051291//protein heterooligomerization;GO:0014070//response to organic cyclic compound;GO:0007596//blood coagulation","K13825//hemoglobin subunit epsilon","XP_002822172.1//PREDICTED: hemoglobin subunit epsilon [Pongo abelii]","3//A2MP1"]
[7062,6995,0.01,0.1,3.32192809488736,0.029506985826972,"*",0.01161512,"TCHH","GO:0005856//cytoskeleton;GO:0005829//cytosol;GO:0001533//cornified envelope","GO:0005509//calcium ion binding;GO:0046914//transition metal ion binding","GO:0070268//cornification","K18626//trichohyalin","NP_009044.2//trichohyalin [Homo sapiens]","3//A2MP1"]
[4689,1551,0.01,0.1,3.32192809488736,0.393818897834042,"*",0.249274,"NCF4","GO:0032010//phagolysosome;GO:0016020//membrane;GO:0010008//endosome membrane;GO:0043020//NADPH oxidase complex;GO:0005829//cytosol;GO:0005802//trans-Golgi network","GO:0016176//superoxide-generating NADPH oxidase activator activity;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0005086//ARF guanyl-nucleotide exchange factor activity;GO:0046983//protein dimerization activity","GO:0055114//oxidation-reduction process;GO:0016192//vesicle-mediated transport;GO:0045730//respiratory burst;GO:0045454//cell redox homeostasis;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0034599//cellular response to oxidative stress;GO:0006955//immune response;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0006909//phagocytosis","K08012//neutrophil cytosolic factor 4","NP_038202.2//neutrophil cytosol factor 4 isoform 2 [Homo sapiens];NP_000622.2//neutrophil cytosol factor 4 isoform 1 [Homo sapiens]","4;3//A2MP1"]
[56287,820,0.01,0.1,3.32192809488736,0.646725390881064,"*",0.499032,"GKN1","GO:0005615//extracellular space","NA","GO:0007586//digestion;GO:0042127//regulation of cell proliferation;GO:0051781//positive regulation of cell division","K20909//anthrax toxin receptor","NP_062563.3//gastrokine-1 [Homo sapiens]","3//A2MP1"]
[169355,2294,0.01,0.1,3.32192809488736,0.226437633014572,"*",0.1245166,"IDO2","GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0020037//heme binding;GO:0033754//indoleamine 2,3-dioxygenase activity;GO:0004833//tryptophan 2,3-dioxygenase activity","GO:0002376//immune system process;GO:0006569//tryptophan catabolic process;GO:0019441//tryptophan catabolic process to kynurenine","K00463//indoleamine 2,3-dioxygenase [EC:1.13.11.52]","NP_919270.2//indoleamine 2,3-dioxygenase 2 [Homo sapiens]","2//1"]
[4635,855,0.01,0.1,3.32192809488736,0.646620471122648,"*",0.499032,"MYL4","NA","NA","NA","K12750//myosin light chain 4","XP_004374303.1//PREDICTED: myosin light chain 4 [Trichechus manatus latirostris];XP_017738431.1//PREDICTED: myosin light chain 4 isoform X1 [Rhinopithecus bieti]","1//3;2//1"]
[10278,3082,0.01,0.1,3.32192809488736,0.127574582948125,"*",0.062198,"EFS","GO:0005737//cytoplasm","GO:0019904//protein domain specific binding;GO:0017124//SH3 domain binding","GO:0007155//cell adhesion;GO:0035556//intracellular signal transduction","K05726//breast cancer anti-estrogen resistance 1","NP_005855.1//embryonal Fyn-associated substrate isoform 1 [Homo sapiens];NP_001264103.1//embryonal Fyn-associated substrate isoform 3 [Homo sapiens];NP_115835.1//embryonal Fyn-associated substrate isoform 2 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[9992,809,0.01,0.1,3.32192809488736,0.64385244875212,"*",0.499032,"KCNE2","GO:0005783//endoplasmic reticulum;GO:0009986//cell surface;GO:0005794//Golgi apparatus;GO:0005764//lysosome;GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex","GO:0044325//ion channel binding;GO:0015459//potassium channel regulator activity;GO:0005242//inward rectifier potassium channel activity;GO:1902282//voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization;GO:0005251//delayed rectifier potassium channel activity;GO:0042803//protein homodimerization activity","GO:1902260//negative regulation of delayed rectifier potassium channel activity;GO:0086009//membrane repolarization;GO:0035690//cellular response to drug;GO:1901379//regulation of potassium ion transmembrane transport;GO:1901800//positive regulation of proteasomal protein catabolic process;GO:1902259//regulation of delayed rectifier potassium channel activity;GO:0071435//potassium ion export;GO:1901979//regulation of inward rectifier potassium channel activity;GO:0060307//regulation of ventricular cardiac muscle cell membrane repolarization;GO:0086005//ventricular cardiac muscle cell action potential;GO:0061337//cardiac conduction;GO:1901387//positive regulation of voltage-gated calcium channel activity;GO:1902159//regulation of cyclic nucleotide-gated ion channel activity;GO:0086091//regulation of heart rate by cardiac conduction;GO:0086002//cardiac muscle cell action potential involved in contraction;GO:0007568//aging;GO:0010107//potassium ion import;GO:0043586//tongue development;GO:0098915//membrane repolarization during ventricular cardiac muscle cell action potential;GO:0060306//regulation of membrane repolarization;GO:0086011//membrane repolarization during action potential;GO:0071805//potassium ion transmembrane transport","K04896//potassium voltage-gated channel Isk-related subfamily E member 2","XP_018873175.1//PREDICTED: potassium voltage-gated channel subfamily E member 2 isoform X1 [Gorilla gorilla gorilla]","1//3"]
[474354,1642,0.01,0.1,3.32192809488736,0.392228415681639,"*",0.249274,"LRRC18","GO:0005737//cytoplasm","NA","GO:0007165//signal transduction","K10130//leucine-rich repeats and death domain-containing protein","NP_001006940.3//leucine-rich repeat-containing protein 18 [Homo sapiens]","3//A2MP1"]
[646951,819,0.01,0.1,3.32192809488736,0.641830689855072,"*",0.499032,"MINDY4B","NA","NA","NA","K08742//E3 ubiquitin-protein ligase SIAH2 [EC:2.3.2.27]","XP_016863110.1//PREDICTED: protein FAM188B2 [Homo sapiens]","1//3"]
[4118,859,0.01,0.1,3.32192809488736,0.640232685567424,"*",0.499032,"MAL","GO:0005783//endoplasmic reticulum;GO:0045121//membrane raft;GO:0016324//apical plasma membrane;GO:0019898//extrinsic component of membrane;GO:0016021//integral component of membrane","GO:0008289//lipid binding;GO:0016505//peptidase activator activity involved in apoptotic process;GO:0019911//structural constituent of myelin sheath","GO:0042552//myelination;GO:1902043//positive regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0001766//membrane raft polarization;GO:0030154//cell differentiation;GO:0008104//protein localization;GO:0007417//central nervous system development;GO:0006915//apoptotic process;GO:0045176//apical protein localization","NA","EAX10707.1//mal, T-cell differentiation protein, isoform CRA_b [Homo sapiens];NP_002362.1//myelin and lymphocyte protein isoform a [Homo sapiens]","3//A2MP1;2//1"]
[3567,816,0.01,0.1,3.32192809488736,0.639154679923028,"*",0.499032,"IL5","GO:0005615//extracellular space;GO:0005622//intracellular;GO:0005576//extracellular region","GO:0004713//protein tyrosine kinase activity;GO:0005137//interleukin-5 receptor binding;GO:0008083//growth factor activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005125//cytokine activity","GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0000165//MAPK cascade;GO:0071803//positive regulation of podosome assembly;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006954//inflammatory response;GO:0030890//positive regulation of B cell proliferation;GO:0046427//positive regulation of JAK-STAT cascade;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0051024//positive regulation of immunoglobulin secretion;GO:0045645//positive regulation of eosinophil differentiation;GO:0006955//immune response;GO:0019221//cytokine-mediated signaling pathway","K05428//interleukin 5","XP_005272045.1//PREDICTED: interleukin-5 isoform X1 [Homo sapiens]","2//1"]
[710,1832,0.31,3.07,3.3078985349833,{"v":2.29756963610451e-13,"d":"2.30E-13"},"Up",{"v":1.816596e-14,"d":"1.82E-14"},"SERPING1","GO:0031093//platelet alpha granule lumen;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0072562//blood microparticle;GO:0005576//extracellular region","GO:0004867//serine-type endopeptidase inhibitor activity","GO:0042730//fibrinolysis;GO:0030449//regulation of complement activation;GO:0007597//blood coagulation, intrinsic pathway;GO:0007568//aging;GO:0030193//regulation of blood coagulation;GO:0008015//blood circulation;GO:0006958//complement activation, classical pathway;GO:0001869//negative regulation of complement activation, lectin pathway;GO:0045916//negative regulation of complement activation;GO:0002576//platelet degranulation;GO:0045087//innate immune response","K04001//C1 inhibitor","BAD93063.1//Plasma protease C1 inhibitor precursor variant, partial [Homo sapiens]","1//3;2//1"]
[22977,1301,0.07,0.68,3.28010791919274,0.0170756626666667,"*",0.00628552,"AKR7A3","GO:0070062//extracellular exosome;GO:0005829//cytosol","GO:0009055//electron transfer activity;GO:0042802//identical protein binding;GO:0004033//aldo-keto reductase (NADP) activity","GO:0006081//cellular aldehyde metabolic process;GO:0006805//xenobiotic metabolic process","K15303//aflatoxin B1 aldehyde reductase","NP_036199.2//aflatoxin B1 aldehyde reductase member 3 [Homo sapiens]","2//1"]
[647219,1420,0.06,0.57,3.24792751344359,0.0170785671848954,"*",0.00628552,"ASCL5","NA","GO:0003677//DNA binding;GO:0046983//protein dimerization activity","NA","K09067//achaete-scute complex protein","Q7RTU5.2//RecName: Full=Achaete-scute homolog 5; Short=ASH-5; Short=hASH5; AltName: Full=Class A basic helix-loop-helix protein 47; Short=bHLHa47","1//3"]
[6398,2282,0.28,2.56,3.1926450779424,{"v":1.96763757607656e-13,"d":"1.97E-13"},"Up",{"v":1.544646E-14,"d":"1.54E-14"},"SECTM1","NA","NA","NA","K06457//T-cell surface glycoprotein CD7;K22020//mucin-19","XP_012358039.1//PREDICTED: LOW QUALITY PROTEIN: secreted and transmembrane protein 1 [Nomascus leucogenys]","2//1"]
[29970,1848,0.47,4.27,3.18350340794285,{"v":2.83145216075949e-17,"d":"2.83E-17"},"Up",{"v":1.680366E-18,"d":"1.68E-18"},"SCHIP1","NA","GO:0042802//identical protein binding","NA","K19475//WAS/WASL-interacting protein;K05747//Wiskott-Aldrich syndrome protein;K21125//mucin-5AC;K16882//protein piccolo","NP_001184036.1//schwannomin-interacting protein 1 isoform 2 [Homo sapiens];NP_055390.1//schwannomin-interacting protein 1 isoform 1 [Homo sapiens];NP_001184037.1//schwannomin-interacting protein 1 isoform 3 [Homo sapiens];EDL15509.1//schwannomin interacting protein 1, partial [Mus musculus]","1//3;3//A2MP1"]
[401409,952,0.01,0.09,3.16992500144231,0.656093594074074,"*",0.499032,"RAB19","GO:0070062//extracellular exosome;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane","GO:0005525//GTP binding;GO:0003924//GTPase activity","NA","K17047//Ras-related protein Rab-19","NP_001008749.2//ras-related protein Rab-19 [Homo sapiens]","2//1"]
[926,944,0.01,0.09,3.16992500144231,0.654800161655988,"*",0.499032,"CD8B","GO:0042101//T cell receptor complex;GO:0031901//early endosome membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0042288//MHC class I protein binding;GO:0015026//coreceptor activity","GO:0042110//T cell activation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0050690//regulation of defense response to virus by virus;GO:0006955//immune response;GO:0050776//regulation of immune response;GO:0002250//adaptive immune response","K06459//T-cell surface glycoprotein CD8 beta chain","NP_757362.1//T-cell surface glycoprotein CD8 beta chain isoform 2 precursor [Homo sapiens];NP_742100.1//T-cell surface glycoprotein CD8 beta chain isoform 4 precursor [Homo sapiens];NP_001171571.1//T-cell surface glycoprotein CD8 beta chain isoform 6 precursor [Homo sapiens];NP_004922.1//T-cell surface glycoprotein CD8 beta chain isoform 5 precursor [Homo sapiens]","4;1//3;3//A2MP1"]
[9087,1702,0.01,0.09,3.16992500144231,0.395422331281033,"*",0.249274,"TMSB4Y","GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0005829//cytosol","GO:0003785//actin monomer binding","GO:0008064//regulation of actin polymerization or depolymerization;GO:0007015//actin filament organization;GO:0030334//regulation of cell migration;GO:0042989//sequestering of actin monomers","K05764//thymosin, beta 4","EAW91614.1//thymosin, beta 4, Y-linked, partial [Homo sapiens]","2//1"]
[23428,3448,0.03,0.27,3.16992500144231,0.00555591868998655,"*",1.809656E-3,"SLC7A8","GO:0070062//extracellular exosome;GO:0016323//basolateral plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0019534//toxin transmembrane transporter activity;GO:0015175//neutral amino acid transmembrane transporter activity;GO:0042605//peptide antigen binding;GO:0015101//organic cation transmembrane transporter activity;GO:0015179//L-amino acid transmembrane transporter activity;GO:0015297//antiporter activity;GO:0015171//amino acid transmembrane transporter activity","GO:0006810//transport;GO:0055065//metal ion homeostasis;GO:0006865//amino acid transport;GO:0050900//leukocyte migration;GO:0006520//cellular amino acid metabolic process;GO:0015804//neutral amino acid transport;GO:0009636//response to toxic substance","K13781//solute carrier family 7 (L-type amino acid transporter), member 8","CAD62616.1//unnamed protein product, partial [Homo sapiens];NP_001253966.1//large neutral amino acids transporter small subunit 2 isoform d [Homo sapiens];XP_010376698.1//PREDICTED: large neutral amino acids transporter small subunit 2 isoform X1 [Rhinopithecus roxellana];NP_001253965.1//large neutral amino acids transporter small subunit 2 isoform c [Homo sapiens]","1//3;3//A2MP1;2//1"]
[26693,948,0.01,0.09,3.16992500144231,0.651695321124918,"*",0.499032,"OR2V1","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity","NA","K04257//olfactory receptor","XP_003900702.1//olfactory receptor 2V1-like [Papio anubis]","1//3"]
[8843,2152,0.01,0.09,3.16992500144231,0.394638540733399,"*",0.249274,"HCAR3","GO:0005887//integral component of plasma membrane;GO:0030054//cell junction;GO:0005886//plasma membrane","GO:0004930//G-protein coupled receptor activity","GO:0007186//G-protein coupled receptor signaling pathway","K08402//G protein-coupled receptor 109","NP_006009.2//hydroxycarboxylic acid receptor 3 [Homo sapiens]","2//1"]
[285051,891,0.01,0.09,3.16992500144231,0.650737728,"*",0.499032,"STPG4","GO:0005634//nucleus;GO:0001939//female pronucleus;GO:0042585//germinal vesicle;GO:0001940//male pronucleus;GO:0005737//cytoplasm","GO:0003682//chromatin binding","GO:0016569//covalent chromatin modification;GO:1901537//positive regulation of DNA demethylation;GO:0044727//DNA demethylation of male pronucleus","NA","NP_775920.1//protein STPG4 isoform 2 [Homo sapiens];NP_001157033.1//protein STPG4 isoform 1 [Homo sapiens]","1//3;2//1"]
[2348,962,0.01,0.09,3.16992500144231,0.650206946818923,"*",0.499032,"FOLR1","GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0031526//brush border membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0000139//Golgi membrane;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0046658//anchored component of plasma membrane;GO:0005886//plasma membrane;GO:0070062//extracellular exosome;GO:0031362//anchored component of external side of plasma membrane;GO:0005634//nucleus;GO:0030136//clathrin-coated vesicle;GO:0005768//endosome;GO:0009986//cell surface;GO:0030133//transport vesicle;GO:0005789//endoplasmic reticulum membrane;GO:0012507//ER to Golgi transport vesicle membrane","GO:0005542//folic acid binding;GO:0051870//methotrexate binding;GO:0004872//receptor activity;GO:0008517//folic acid transmembrane transporter activity;GO:0008144//drug binding;GO:0061714//folic acid receptor activity","GO:0031103//axon regeneration;GO:0071231//cellular response to folic acid;GO:0061626//pharyngeal arch artery morphogenesis;GO:0015884//folic acid transport;GO:0061713//anterior neural tube closure;GO:0048208//COPII vesicle coating;GO:0017015//regulation of transforming growth factor beta receptor signaling pathway;GO:0001947//heart looping;GO:0060828//regulation of canonical Wnt signaling pathway;GO:0006898//receptor-mediated endocytosis;GO:0003147//neural crest cell migration involved in heart formation;GO:0003253//cardiac neural crest cell migration involved in outflow tract morphogenesis;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0046655//folic acid metabolic process","K13649//folate receptor","NP_000793.1//folate receptor alpha precursor [Homo sapiens]","3//A2MP1;2//1"]
[1193,2694,0.01,0.09,3.16992500144231,0.226540793667426,"*",0.1245166,"CLIC2","GO:0005634//nucleus;GO:0005622//intracellular;GO:0034707//chloride channel complex;GO:0005737//cytoplasm","GO:0005244//voltage-gated ion channel activity;GO:0004602//glutathione peroxidase activity;GO:0005254//chloride channel activity","GO:0006810//transport;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0007165//signal transduction;GO:0010881//regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion;GO:0051099//positive regulation of binding;GO:0060315//negative regulation of ryanodine-sensitive calcium-release channel activity;GO:1902476//chloride transmembrane transport","K05022//chloride intracellular channel protein 2","NP_001280.3//chloride intracellular channel protein 2 [Homo sapiens]",5]
[29949,1848,0.01,0.09,3.16992500144231,0.393390918395574,"*",0.249274,"IL19","GO:0005615//extracellular space;GO:0005576//extracellular region","GO:0005125//cytokine activity","GO:0007165//signal transduction;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:0006955//immune response;GO:0072593//reactive oxygen species metabolic process;GO:0042226//interleukin-6 biosynthetic process;GO:0006915//apoptotic process","K05444//interleukin 19/20/24","NP_715639.1//interleukin-19 isoform 1 [Homo sapiens]","3//A2MP1;2//1"]
[137735,2831,0.01,0.09,3.16992500144231,0.22648920159417,"*",0.1245166,"ABRA","GO:0015629//actin cytoskeleton;GO:0030016//myofibril;GO:0030017//sarcomere;GO:0005886//plasma membrane","GO:0003779//actin binding","GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0035025//positive regulation of Rho protein signal transduction;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0000060//protein import into nucleus, translocation","K09291//nucleoprotein TPR","NP_631905.1//actin-binding Rho-activating protein [Homo sapiens]",4]
[3816,886,0.01,0.09,3.16992500144231,0.645102951201748,"*",0.499032,"KLK1","GO:0070062//extracellular exosome;GO:0005634//nucleus","GO:0004252//serine-type endopeptidase activity","NA","K01325//tissue kallikrein [EC:3.4.21.35]","NP_002248.1//kallikrein-1 preproprotein [Homo sapiens]","3//A2MP1"]
[338382,2955,0.06,0.54,3.16992500144231,0.000455418969621466,"Up",0.0001190008,"RAB7B","GO:0045335//phagocytic vesicle;GO:0005770//late endosome;GO:0005794//Golgi apparatus;GO:0031902//late endosome membrane;GO:0030670//phagocytic vesicle membrane;GO:0005764//lysosome;GO:0005802//trans-Golgi network","GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0032755//positive regulation of interleukin-6 production;GO:0034499//late endosome to Golgi transport;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0034144//negative regulation of toll-like receptor 4 signaling pathway;GO:0045654//positive regulation of megakaryocyte differentiation;GO:0034164//negative regulation of toll-like receptor 9 signaling pathway;GO:0015031//protein transport;GO:0061024//membrane organization","K07898//Ras-related protein Rab-7B","XP_014925443.1//PREDICTED: ras-related protein Rab-7b [Acinonyx jubatus];NP_001291768.1//ras-related protein Rab-7b isoform b [Homo sapiens]","1//3;2//1;5"]
[79541,1758,0.01,0.09,3.16992500144231,0.392537744085174,"*",0.249274,"OR2A4","NA","NA","NA","K04257//olfactory receptor","XP_012367550.1//PREDICTED: LOW QUALITY PROTEIN: olfactory receptor 2A7 [Nomascus leucogenys]","2//1"]
[29118,1967,0.01,0.09,3.16992500144231,0.392267055068466,"*",0.249274,"DDX25","GO:0005634//nucleus;GO:0033391//chromatoid body","GO:0004004//ATP-dependent RNA helicase activity;GO:0005524//ATP binding;GO:0003676//nucleic acid binding","GO:0006406//mRNA export from nucleus;GO:0007286//spermatid development;GO:0006417//regulation of translation","K18656//ATP-dependent RNA helicase DDX25 [EC:3.6.4.13]","XP_003923580.1//PREDICTED: ATP-dependent RNA helicase DDX25 [Saimiri boliviensis boliviensis]","1//3;4"]
[4935,1711,0.01,0.09,3.16992500144231,0.392189783906235,"*",0.249274,"GPR143","GO:0016020//membrane;GO:0005765//lysosomal membrane;GO:0016324//apical plasma membrane;GO:0033162//melanosome membrane;GO:0042470//melanosome;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0072544//L-DOPA binding;GO:0035643//L-DOPA receptor activity;GO:0072545//tyrosine binding;GO:0035240//dopamine binding;GO:0004930//G-protein coupled receptor activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0007165//signal transduction;GO:0007601//visual perception;GO:0035584//calcium-mediated signaling using intracellular calcium source;GO:0032400//melanosome localization;GO:1903056//regulation of melanosome organization;GO:0032402//melanosome transport;GO:1902908//regulation of melanosome transport;GO:0050848//regulation of calcium-mediated signaling;GO:0006726//eye pigment biosynthetic process;GO:0048015//phosphatidylinositol-mediated signaling;GO:0032438//melanosome organization","K08470//Ocular albinism type 1 protein","CAA88742.1//OA1 [Homo sapiens]","2//1"]
[255798,1812,0.01,0.09,3.16992500144231,0.392151159740004,"*",0.249274,"SMCO1","GO:0016021//integral component of membrane","NA","NA","NA","NP_001307402.1//single-pass membrane and coiled-coil domain-containing protein 1 isoform 2 [Homo sapiens];NP_001071125.1//single-pass membrane and coiled-coil domain-containing protein 1 isoform 1 [Homo sapiens]","1//3;2//1"]
[254773,880,0.01,0.09,3.16992500144231,0.641417538461538,"*",0.499032,"LYG2","NA","NA","NA","K01446//peptidoglycan recognition protein","XP_008006348.1//PREDICTED: lysozyme g-like protein 2 isoform X3 [Chlorocebus sabaeus]","3//A2MP1"]
[390883,939,0.01,0.09,3.16992500144231,0.640027070895223,"*",0.499032,"OR7G3","NA","NA","NA","K04257//olfactory receptor","XP_004059995.2//PREDICTED: olfactory receptor 7G3 [Gorilla gorilla gorilla]","1//3"]
[54855,5720,0.03,0.26,3.11547721741994,0.000455309887233533,"Up",0.0001190008,"FAM46C","NA","NA","NA","K05742//solute carrier family 9 (sodium/hydrogen exchanger), member 1","XP_011945349.1//PREDICTED: protein FAM46C isoform X1 [Cercocebus atys]","3//A2MP1"]
[3433,3505,0.16,1.38,3.10852445677817,{"v":4.05235267579909e-11,"d":"4.05E-11"},"Up",{"v":3.88898e-12,"d":"3.89E-12"},"IFIT2","GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0003723//RNA binding","GO:0060337//type I interferon signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0032091//negative regulation of protein binding;GO:0051607//defense response to virus;GO:0008637//apoptotic mitochondrial changes;GO:0009615//response to virus;GO:0035457//cellular response to interferon-alpha","K14217//interferon-induced protein with tetratricopeptide repeats 1","AAH32839.2//Interferon-induced protein with tetratricopeptide repeats 2 [Homo sapiens]",4]
[441108,805,0.41,3.52,3.10187961401921,{"v":1.88216649040203e-06,"d":"1.88E-06"},"Up",{"v":3.2532E-7,"d":"3.25E-07"},"C5orf56","NA","NA","NA","NA","XP_005557781.1//PREDICTED: uncharacterized protein LOC102122672 isoform X2 [Macaca fascicularis]","2//1"]
[27063,1994,0.89,7.49,3.07308847749235,{"v":2.95588382020202e-32,"d":"2.96E-32"},"Up",{"v":7.32772e-34,"d":"7.33E-34"},"ANKRD1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription factor complex;GO:0005829//cytosol;GO:0031674//I band;GO:0001650//fibrillar center;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0001105//RNA polymerase II transcription coactivator activity;GO:0002039//p53 binding;GO:0042826//histone deacetylase binding;GO:0061629//RNA polymerase II sequence-specific DNA binding transcription factor binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0070412//R-SMAD binding;GO:0031432//titin binding","GO:0071456//cellular response to hypoxia;GO:0071260//cellular response to mechanical stimulus;GO:0035690//cellular response to drug;GO:0071222//cellular response to lipopolysaccharide;GO:0071356//cellular response to tumor necrosis factor;GO:0055008//cardiac muscle tissue morphogenesis;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0043065//positive regulation of apoptotic process;GO:0045445//myoblast differentiation;GO:0071347//cellular response to interleukin-1;GO:0071407//cellular response to organic cyclic compound;GO:0019216//regulation of lipid metabolic process;GO:0043517//positive regulation of DNA damage response, signal transduction by p53 class mediator;GO:0035994//response to muscle stretch;GO:0045214//sarcomere organization;GO:0010976//positive regulation of neuron projection development;GO:2000279//negative regulation of DNA biosynthetic process;GO:0050714//positive regulation of protein secretion;GO:0035914//skeletal muscle cell differentiation","K21433//ankyrin repeat domain-containing protein 1","NP_055206.2//ankyrin repeat domain-containing protein 1 [Homo sapiens]","2//1"]
[3426,2196,0.04,0.33,3.04439411935845,0.0294976036375199,"*",0.01161512,"CFI","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005576//extracellular region","GO:0004252//serine-type endopeptidase activity;GO:0046872//metal ion binding;GO:0005044//scavenger receptor activity","GO:0006958//complement activation, classical pathway;GO:0030449//regulation of complement activation;GO:0045087//innate immune response","K01333//complement factor I [EC:3.4.21.45]","NP_000195.2//complement factor I isoform 2 preproprotein [Homo sapiens];NP_001317964.1//complement factor I isoform 3 preproprotein [Homo sapiens];NP_001304986.1//complement factor I isoform 1 preproprotein [Homo sapiens]","1//3;4"]
[388436,1915,0.31,2.54,3.03448837638529,{"v":7.10884583111111e-11,"d":"7.11E-11"},"Up",{"v":7.00916E-12,"d":"7.01E-12"},"LOC388436","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein;K12581//CCR4-NOT transcription complex subunit 7/8","NP_001278833.2//uncharacterized protein ENSP00000382033 [Homo sapiens]","2//1"]
[100141515,1090,0.01,0.08,3,0.655985612903226,"*",0.499032,"C17orf99","GO:0005576//extracellular region","NA","NA","K21988//transmembrane channel-like protein","NP_001156547.1//uncharacterized protein C17orf99 precursor [Homo sapiens]","1//3"]
[3761,1913,0.01,0.08,3,0.395618765623448,"*",0.249274,"KCNJ4","GO:0016323//basolateral plasma membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0045211//postsynaptic membrane;GO:0030659//cytoplasmic vesicle membrane","GO:0005242//inward rectifier potassium channel activity;GO:0015467//G-protein activated inward rectifier potassium channel activity;GO:0030165//PDZ domain binding","GO:0006813//potassium ion transport;GO:0061337//cardiac conduction;GO:0010107//potassium ion import","K04998//potassium inwardly-rectifying channel subfamily J member 4","NP_004972.1//inward rectifier potassium channel 4 [Homo sapiens]","1//3;2//1"]
[3823,1042,0.01,0.08,3,0.654692605781866,"*",0.499032,"KLRC3","GO:0016021//integral component of membrane","GO:0030246//carbohydrate binding;GO:0004888//transmembrane signaling receptor activity","GO:0006968//cellular defense response","K06541//killer cell lectin-like receptor subfamily C","NP_031359.2//NKG2-E type II integral membrane protein isoform H [Homo sapiens];NP_002252.2//NKG2-E type II integral membrane protein isoform E [Homo sapiens]","2//1"]
[400757,2177,0.01,0.08,3,0.395461602542457,"*",0.249274,"C1orf141","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein;K04948//cyclic nucleotide gated channel alpha 1","NP_001263281.1//uncharacterized protein C1orf141 isoform 2 [Homo sapiens];NP_001263280.1//uncharacterized protein C1orf141 isoform 1 [Homo sapiens]","1//3"]
[64108,1027,0.01,0.08,3,0.652015145427777,"*",0.499032,"RTP4","GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0005737//cytoplasm","GO:0031849//olfactory receptor binding","GO:0006612//protein targeting to membrane;GO:0051607//defense response to virus;GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0051205//protein insertion into membrane","NA","NP_071430.2//receptor-transporting protein 4 [Homo sapiens]","2//1"]
[339834,2696,0.01,0.08,3,0.226824970737826,"*",0.1245166,"CCDC36","GO:0000794//condensed nuclear chromosome","NA","GO:0007129//synapsis;GO:0042138//meiotic DNA double-strand break formation;GO:0060629//regulation of homologous chromosome segregation;GO:0048477//oogenesis;GO:0007283//spermatogenesis;GO:0006310//DNA recombination","NA","NP_835467.2//interactor of HORMAD1 protein 1 [Homo sapiens]","1//3;3//A2MP1"]
[171169,978,0.01,0.08,3,0.649835914893617,"*",0.499032,"SPACA4","GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0001669//acrosomal vesicle;GO:0005886//plasma membrane;GO:0031225//anchored component of membrane","GO:0003796//lysozyme activity","GO:0007155//cell adhesion;GO:0006501//C-terminal protein lipidation;GO:0050829//defense response to Gram-negative bacterium;GO:0016998//cell wall macromolecule catabolic process;GO:0050830//defense response to Gram-positive bacterium","K19894//sperm acrosome membrane-associated protein 4","NP_598005.1//sperm acrosome membrane-associated protein 4 precursor [Homo sapiens]","2//1"]
[387778,991,0.01,0.08,3,0.649147977850163,"*",0.499032,"SPDYC","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0019901//protein kinase binding","GO:0007049//cell cycle","K08694//speedy","XP_003828661.2//PREDICTED: speedy protein C [Pan paniscus]","2//1"]
[400668,1075,0.01,0.08,3,0.648989429943825,"*",0.499032,"PRSS57","GO:0005615//extracellular space;GO:0035578//azurophil granule lumen","GO:0004252//serine-type endopeptidase activity;GO:0008201//heparin binding;GO:0008236//serine-type peptidase activity","GO:0006508//proteolysis","K01334//component factor D [EC:3.4.21.46]","NP_001295138.1//serine protease 57 isoform 2 precursor [Homo sapiens];NP_999875.1//serine protease 57 isoform 1 precursor [Homo sapiens]","1//3;4"]
[84970,2136,0.01,0.08,3,0.393702083844176,"*",0.249274,"C1orf94","NA","NA","NA","K17495//CUB and sushi domain-containing protein","NP_001128206.1//uncharacterized protein C1orf94 isoform a [Homo sapiens];XP_004025462.2//PREDICTED: uncharacterized protein C1orf94 homolog [Gorilla gorilla gorilla]","4;1//3"]
[285852,2088,0.01,0.08,3,0.393507547781401,"*",0.249274,"TREML4","GO:0005576//extracellular region;GO:0005886//plasma membrane","NA","GO:0034157//positive regulation of toll-like receptor 7 signaling pathway;GO:0045087//innate immune response;GO:0050776//regulation of immune response","K06742//natural cytotoxicity triggering receptor 2;K14364//trem-like transcript 2 protein","NP_937796.1//trem-like transcript 4 protein precursor [Homo sapiens]","2//1"]
[259289,1027,0.01,0.08,3,0.64562542868713,"*",0.499032,"TAS2R43","GO:0060170//ciliary membrane;GO:0031514//motile cilium;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0008527//taste receptor activity;GO:0033038//bitter taste receptor activity;GO:0004930//G-protein coupled receptor activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste","K08474//taste receptor type 2","NP_795365.2//taste receptor type 2 member 43 [Homo sapiens]","2//1"]
[440087,2104,0.01,0.08,3,0.392615152435417,"*",0.249274,"SMCO3","GO:0016021//integral component of membrane","NA","NA","NA","XP_011913868.1//PREDICTED: single-pass membrane and coiled-coil domain-containing protein 3 isoform X1 [Cercocebus atys]","2//1"]
[256223,1051,0.01,0.08,3,0.64167569572567,"*",0.499032,"CDRT15L2","GO:0016021//integral component of membrane","NA","NA","NA","NP_001177719.1//CMT1A duplicated region transcript 15 protein-like protein [Homo sapiens]","1//3"]
[1581,2875,0.01,0.08,3,0.226051615910899,"*",0.1245166,"CYP7A1","GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0020037//heme binding;GO:0008123//cholesterol 7-alpha-monooxygenase activity;GO:0005506//iron ion binding","GO:0071333//cellular response to glucose stimulus;GO:0071397//cellular response to cholesterol;GO:0006707//cholesterol catabolic process;GO:0019216//regulation of lipid metabolic process;GO:0070857//regulation of bile acid biosynthetic process;GO:0042632//cholesterol homeostasis;GO:0016125//sterol metabolic process;GO:0006699//bile acid biosynthetic process","K00489//cholesterol 7alpha-monooxygenase [EC:1.14.14.23]","NP_000771.2//cholesterol 7-alpha-monooxygenase [Homo sapiens]","3//A2MP1"]
[3753,3151,0.01,0.08,3,0.226025928227273,"*",0.1245166,"KCNE1","NA","NA","NA","K04894//potassium voltage-gated channel Isk-related subfamily E member 1","XP_011724448.1//PREDICTED: potassium voltage-gated channel subfamily E member 1 isoform X1 [Macaca nemestrina];XP_016883831.1//PREDICTED: potassium voltage-gated channel subfamily E member 1 isoform X1 [Homo sapiens]","3//A2MP1;2//1;5"]
[2636,1092,0.01,0.08,3,0.639308458416874,"*",0.499032,"GBX1","GO:0005634//nucleus","GO:0043565//sequence-specific DNA binding","GO:0097374//sensory neuron axon guidance;GO:0006355//regulation of transcription, DNA-templated;GO:0007628//adult walking behavior;GO:0021522//spinal cord motor neuron differentiation;GO:0019230//proprioception;GO:0048663//neuron fate commitment;GO:0006351//transcription, DNA-templated","K09321//homeobox protein GBX","NP_001092304.1//homeobox protein GBX-1 [Homo sapiens]","2//1"]
[7134,705,0.12,0.95,2.98489310760979,0.0503225857522909,"*",0.0213148,"TNNC1","GO:0005829//cytosol;GO:0043292//contractile fiber;GO:0005861//troponin complex;GO:1990584//cardiac Troponin complex","GO:0051015//actin filament binding;GO:0005509//calcium ion binding;GO:0048306//calcium-dependent protein binding;GO:0042803//protein homodimerization activity;GO:0031014//troponin T binding;GO:0031013//troponin I binding","GO:0032972//regulation of muscle filament sliding speed;GO:0030049//muscle filament sliding;GO:0014883//transition between fast and slow fiber;GO:0002086//diaphragm contraction;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0043462//regulation of ATPase activity;GO:0006937//regulation of muscle contraction;GO:0060048//cardiac muscle contraction;GO:0010038//response to metal ion;GO:0003009//skeletal muscle contraction","K05865//troponin C, slow skeletal and cardiac muscles","EDL24796.1//troponin C, cardiac/slow skeletal, partial [Mus musculus]","2//1"]
[1475,838,0.1,0.79,2.98185265328974,0.0503151492832865,"*",0.0213148,"CSTA","GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0001533//cornified envelope;GO:0005737//cytoplasm","GO:0002020//protease binding;GO:0030674//protein binding, bridging;GO:0005198//structural molecule activity;GO:0004869//cysteine-type endopeptidase inhibitor activity","GO:0018149//peptide cross-linking;GO:0098609//cell-cell adhesion;GO:0010466//negative regulation of peptidase activity;GO:0045861//negative regulation of proteolysis;GO:0030216//keratinocyte differentiation;GO:0070268//cornification","K13907//cystatin-A/B","XP_008706392.1//PREDICTED: cystatin-A isoform X1 [Ursus maritimus]","3//A2MP1"]
[6347,760,100.35,791.62,2.97976744532654,0,"Up",0,"CCL2","GO:0030425//dendrite;GO:0044299//C-fiber;GO:0005615//extracellular space;GO:0030139//endocytic vesicle;GO:0005622//intracellular;GO:0043679//axon terminus","GO:0004672//protein kinase activity;GO:0008201//heparin binding;GO:0031727//CCR2 chemokine receptor binding;GO:0048020//CCR chemokine receptor binding;GO:0008009//chemokine activity","GO:0031100//animal organ regeneration;GO:0043491//protein kinase B signaling;GO:0071356//cellular response to tumor necrosis factor;GO:0071346//cellular response to interferon-gamma;GO:0071347//cellular response to interleukin-1;GO:2000427//positive regulation of apoptotic cell clearance;GO:0010574//regulation of vascular endothelial growth factor production;GO:2000502//negative regulation of natural killer cell chemotaxis;GO:0048246//macrophage chemotaxis;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0009611//response to wounding;GO:0048247//lymphocyte chemotaxis;GO:0035684//helper T cell extravasation;GO:0001525//angiogenesis;GO:0090026//positive regulation of monocyte chemotaxis;GO:0043524//negative regulation of neuron apoptotic process;GO:0070098//chemokine-mediated signaling pathway;GO:0008360//regulation of cell shape;GO:0043615//astrocyte cell migration;GO:0007010//cytoskeleton organization;GO:0019221//cytokine-mediated signaling pathway;GO:0010759//positive regulation of macrophage chemotaxis;GO:0043547//positive regulation of GTPase activity;GO:0090280//positive regulation of calcium ion import;GO:0051770//positive regulation of nitric-oxide synthase biosynthetic process;GO:0071407//cellular response to organic cyclic compound;GO:0002548//monocyte chemotaxis;GO:0090265//positive regulation of immune complex clearance by monocytes and macrophages;GO:0007186//G-protein coupled receptor signaling pathway;GO:0000165//MAPK cascade;GO:0030593//neutrophil chemotaxis;GO:0016525//negative regulation of angiogenesis;GO:0050870//positive regulation of T cell activation;GO:0034351//negative regulation of glial cell apoptotic process;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0006954//inflammatory response;GO:0007568//aging;GO:0009887//animal organ morphogenesis;GO:0006955//immune response;GO:0070374//positive regulation of ERK1 and ERK2 cascade","K14624//C-C motif chemokine 2","XP_008009200.1//PREDICTED: C-C motif chemokine 2 [Chlorocebus sabaeus]","3//A2MP1"]
[100527963,794,0.8,6.29,2.97498811199193,{"v":1.25294175024876e-10,"d":"1.25E-10"},"Up",{"v":1.261256E-11,"d":"1.26E-11"},"PMF1-BGLAP","GO:0043231//intracellular membrane-bounded organelle;GO:0005654//nucleoplasm;GO:0005667//transcription factor complex;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0000777//condensed chromosome kinetochore;GO:0000444//MIS12/MIND type complex","GO:0003713//transcription coactivator activity;GO:0043522//leucine zipper domain binding","GO:0007059//chromosome segregation;GO:0007062//sister chromatid cohesion;GO:0006355//regulation of transcription, DNA-templated;GO:0051301//cell division;GO:0006366//transcription from RNA polymerase II promoter","K11546//polyamine-modulated factor 1","NP_001186592.1//PMF1-BGLAP protein isoform 3 [Homo sapiens];NP_001186591.1//PMF1-BGLAP protein isoform 2 [Homo sapiens];NP_001186593.1//PMF1-BGLAP protein isoform 4 [Homo sapiens];NP_001186590.1//PMF1-BGLAP protein isoform 1 [Homo sapiens]","1//3"]
[389898,1185,0.12,0.94,2.96962635095648,0.00311601906291726,"*",0.000964222,"UBE2NL","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0061630//ubiquitin protein ligase activity;GO:0031625//ubiquitin protein ligase binding","GO:0070534//protein K63-linked ubiquitination;GO:0006301//postreplication repair","K10580//ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]","NP_001013007.1//putative ubiquitin-conjugating enzyme E2 N-like [Homo sapiens]","2//1"]
[810,1417,0.11,0.86,2.9668331360648,0.00408352609441043,"*",0.001294284,"CALML3","GO:0070062//extracellular exosome","GO:0005509//calcium ion binding","NA","K02183//calmodulin","NP_005176.1//calmodulin-like protein 3 [Homo sapiens]","3//A2MP1"]
[84166,6742,0.99,7.7,2.95935801550265,{"v":4.4593703e-109,"d":"4.46E-109"},"Up",{"v":2.34498e-111,"d":"2.34E-111"},"NLRC5","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005813//centrosome;GO:0005737//cytoplasm","GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0005524//ATP binding","GO:0051607//defense response to virus;GO:0045345//positive regulation of MHC class I biosynthetic process;GO:0060335//positive regulation of interferon-gamma-mediated signaling pathway;GO:0060340//positive regulation of type I interferon-mediated signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0032480//negative regulation of type I interferon production;GO:0045087//innate immune response;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0060339//negative regulation of type I interferon-mediated signaling pathway;GO:0043549//regulation of kinase activity","K08060//class II, major histocompatibility complex, transactivator","NP_115582.4//protein NLRC5 isoform 1 [Homo sapiens];NP_001317481.1//protein NLRC5 isoform 2 [Homo sapiens]","4;1//3"]
[110384692,5427,0.04,0.31,2.95419631038687,1.47528484934383E-4,"Up",{"v":3.51874e-05,"d":"3.52E-05"},"LOC110384692","NA","NA","NA","K03989//complement component 4","NP_001338929.1//complement C4A (Rodgers blood group)-like preproprotein [Homo sapiens]","1//3"]
[56165,4510,0.02,0.15,2.90689059560852,0.0503077150118203,"*",0.0213148,"TDRD1","GO:0071546//pi-body;GO:0033391//chromatoid body;GO:0043186//P granule;GO:0005737//cytoplasm","GO:0046872//metal ion binding","GO:0007281//germ cell development;GO:0007275//multicellular organism development;GO:0051321//meiotic cell cycle;GO:0043046//DNA methylation involved in gamete generation;GO:0031047//gene silencing by RNA;GO:0007283//spermatogenesis;GO:0034587//piRNA metabolic process","K18405//tudor domain-containing protein 1/4/6/7","NP_942090.1//tudor domain-containing protein 1 [Homo sapiens]","1//3"]
[9235,917,6.97,49.21,2.81972095526172,{"v":2.89351895e-88,"d":"2.89E-88"},"Up",{"v":2.02876e-90,"d":"2.03E-90"},"IL32","GO:0016020//membrane;GO:0005615//extracellular space;GO:0005829//cytosol","GO:0005125//cytokine activity","GO:0007155//cell adhesion;GO:0006952//defense response;GO:0006955//immune response","NA","NP_001012649.1//interleukin-32 isoform B [Homo sapiens];NP_001295007.1//interleukin-32 isoform E precursor [Homo sapiens];XP_016784733.1//PREDICTED: interleukin-32 isoform X3 [Pan troglodytes];NP_001012652.1//interleukin-32 isoform C [Homo sapiens];NP_001012654.1//interleukin-32 isoform D [Homo sapiens]","4;1//3"]
[3123,1280,0.01,0.07,2.8073549220576,0.654907752875452,"*",0.499032,"HLA-DRB1","NA","NA","NA","K06752//major histocompatibility complex, class II","AAU87993.1//MHC class II antigen [Homo sapiens];Q9TQE0.1//RecName: Full=HLA class II histocompatibility antigen, DRB1-9 beta chain; AltName: Full=MHC class II antigen DRB1*9; Short=DR-9; Short=DR9; Flags: Precursor;AAB63307.1//MHC class II DRB [Macaca mulatta];CDR98297.1//MHC class II antigen [Homo sapiens]","1//3;3//A2MP1"]
[6540,2226,0.01,0.07,2.8073549220576,0.395540168471243,"*",0.249274,"SLC6A13","GO:0070062//extracellular exosome;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane","GO:0005332//gamma-aminobutyric acid:sodium symporter activity;GO:0005328//neurotransmitter:sodium symporter activity;GO:0005215//transporter activity","GO:0006810//transport","K05039//solute carrier family 6 (neurotransmitter transporter, GABA) member 6/8/11/12/13","XP_016778176.1//PREDICTED: sodium- and chloride-dependent GABA transporter 2 isoform X1 [Pan troglodytes];XP_011822522.1//PREDICTED: sodium- and chloride-dependent GABA transporter 2 [Mandrillus leucophaeus];NP_001230321.1//sodium- and chloride-dependent GABA transporter 2 isoform 3 [Homo sapiens]","1//3;4;2//1"]
[353132,1197,0.01,0.07,2.8073549220576,0.654370150057462,"*",0.499032,"LCE1B","GO:0001533//cornified envelope;GO:0005737//cytoplasm","GO:0005198//structural molecule activity","GO:0018149//peptide cross-linking;GO:0030216//keratinocyte differentiation;GO:0031424//keratinization","K10385//loricrin","NP_848126.1//late cornified envelope protein 1B [Homo sapiens]","1//3"]
[3593,2347,0.01,0.07,2.8073549220576,0.395500881605085,"*",0.249274,"IL12B","GO:0016020//membrane;GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0043514//interleukin-12 complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005576//extracellular region;GO:0070743//interleukin-23 complex","GO:0008083//growth factor activity;GO:0045519//interleukin-23 receptor binding;GO:0005125//cytokine activity;GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity;GO:0004896//cytokine receptor activity;GO:0042803//protein homodimerization activity;GO:0042164//interleukin-12 alpha subunit binding","GO:0016477//cell migration;GO:0071222//cellular response to lipopolysaccharide;GO:0032740//positive regulation of interleukin-17 production;GO:0045672//positive regulation of osteoclast differentiation;GO:0071346//cellular response to interferon-gamma;GO:0032760//positive regulation of tumor necrosis factor production;GO:0035744//T-helper 1 cell cytokine production;GO:0002827//positive regulation of T-helper 1 type immune response;GO:0032729//positive regulation of interferon-gamma production;GO:0042104//positive regulation of activated T cell proliferation;GO:0002860//positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target;GO:0010536//positive regulation of activation of Janus kinase activity;GO:0034393//positive regulation of smooth muscle cell apoptotic process;GO:0032609//interferon-gamma production;GO:0042093//T-helper cell differentiation;GO:0032725//positive regulation of granulocyte macrophage colony-stimulating factor production;GO:0030101//natural killer cell activation;GO:0044130//negative regulation of growth of symbiont in host;GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0032733//positive regulation of interleukin-10 production;GO:0050829//defense response to Gram-negative bacterium;GO:0032693//negative regulation of interleukin-10 production;GO:0032819//positive regulation of natural killer cell proliferation;GO:0007050//cell cycle arrest;GO:0008283//cell proliferation;GO:0032735//positive regulation of interleukin-12 production;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0042832//defense response to protozoan;GO:0051607//defense response to virus;GO:0010224//response to UV-B;GO:0051142//positive regulation of NK T cell proliferation;GO:0002862//negative regulation of inflammatory response to antigenic stimulus;GO:0032700//negative regulation of interleukin-17 production;GO:0002230//positive regulation of defense response to virus by host","K05425//interleukin 12B","NP_002178.2//interleukin-12 subunit beta precursor [Homo sapiens]","2//1"]
[8838,1252,0.01,0.07,2.8073549220576,0.653083497296412,"*",0.499032,"WISP3","GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix","GO:0005520//insulin-like growth factor binding;GO:0008083//growth factor activity;GO:0005178//integrin binding;GO:0008201//heparin binding","GO:0001558//regulation of cell growth;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0060548//negative regulation of cell death","K06827//connective tissue growth factor","XP_012293878.2//WNT1-inducible-signaling pathway protein 3 [Aotus nancymaae];NP_937882.1//WNT1-inducible-signaling pathway protein 3 isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[283129,1121,0.01,0.07,2.8073549220576,0.652709176123803,"*",0.499032,"MAJIN","GO:0000784//nuclear chromosome, telomeric region;GO:0005639//integral component of nuclear inner membrane","GO:0003677//DNA binding","GO:0007129//synapsis;GO:0045141//meiotic telomere clustering;GO:0070197//meiotic attachment of telomere to nuclear envelope","NA","NP_001032302.1//membrane-anchored junction protein isoform 1 [Homo sapiens];XP_005273975.1//PREDICTED: membrane-anchored junction protein isoform X3 [Homo sapiens];NP_001287732.1//membrane-anchored junction protein isoform 2 [Homo sapiens]","1//3;2//1"]
[284359,1505,0.01,0.07,2.8073549220576,0.652335283797054,"*",0.499032,"IZUMO1","GO:0016021//integral component of membrane;GO:0002080//acrosomal membrane;GO:0005886//plasma membrane","GO:0086080//protein binding involved in heterotypic cell-cell adhesion;GO:0042802//identical protein binding;GO:0005102//receptor binding;GO:0042803//protein homodimerization activity","GO:0007155//cell adhesion;GO:0035036//sperm-egg recognition;GO:0007338//single fertilization;GO:0034113//heterotypic cell-cell adhesion;GO:0007342//fusion of sperm to egg plasma membrane involved in single fertilization","NA","EAW52397.1//izumo sperm-egg fusion 1, isoform CRA_c [Homo sapiens];XP_016882135.1//PREDICTED: izumo sperm-egg fusion protein 1 isoform X1 [Homo sapiens]","1//3;2//1"]
[9389,2176,0.01,0.07,2.8073549220576,0.394834196926128,"*",0.249274,"SLC22A14","GO:0005887//integral component of plasma membrane","GO:0015101//organic cation transmembrane transporter activity;GO:0005452//inorganic anion exchanger activity;GO:0015347//sodium-independent organic anion transmembrane transporter activity","GO:0043252//sodium-independent organic anion transport;GO:0015695//organic cation transport","K08210//MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 14","XP_006713479.2//PREDICTED: solute carrier family 22 member 14 isoform X1 [Homo sapiens]","1//3;4"]
[27240,1238,0.01,0.07,2.8073549220576,0.651535526604005,"*",0.499032,"SIT1","GO:0070062//extracellular exosome;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0019900//kinase binding;GO:0042169//SH2 domain binding","GO:0050863//regulation of T cell activation;GO:0043029//T cell homeostasis;GO:0007165//signal transduction;GO:0002250//adaptive immune response","NA","NP_055265.1//signaling threshold-regulating transmembrane adapter 1 precursor [Homo sapiens]","2//1"]
[1029,1164,0.01,0.07,2.8073549220576,0.650843988242978,"*",0.499032,"CDKN2A","GO:0005654//nucleoplasm;GO:0001652//granular component;GO:0005634//nucleus;GO:0035985//senescence-associated heterochromatin focus;GO:0043234//protein complex;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0055105//ubiquitin-protein transferase inhibitor activity;GO:0047485//protein N-terminus binding;GO:0016301//kinase activity;GO:0019901//protein kinase binding;GO:0004861//cyclin-dependent protein serine/threonine kinase inhibitor activity;GO:0051059//NF-kappaB binding;GO:0003700//DNA binding transcription factor activity;GO:0097371//MDM2/MDM4 family protein binding","GO:0051444//negative regulation of ubiquitin-protein transferase activity;GO:0048103//somatic stem cell division;GO:0035019//somatic stem cell population maintenance;GO:0042593//glucose homeostasis;GO:0032091//negative regulation of protein binding;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0070301//cellular response to hydrogen peroxide;GO:0008285//negative regulation of cell proliferation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0035986//senescence-associated heterochromatin focus assembly;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0090399//replicative senescence;GO:0042326//negative regulation of phosphorylation;GO:0034393//positive regulation of smooth muscle cell apoptotic process;GO:0006915//apoptotic process;GO:0008544//epidermis development;GO:2000059//negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0030889//negative regulation of B cell proliferation;GO:0001953//negative regulation of cell-matrix adhesion;GO:0000082//G1/S transition of mitotic cell cycle;GO:0009303//rRNA transcription;GO:0060058//positive regulation of apoptotic process involved in mammary gland involution;GO:0007050//cell cycle arrest;GO:0045893//positive regulation of transcription, DNA-templated;GO:0033088//negative regulation of immature T cell proliferation in thymus;GO:0090398//cellular senescence;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0030308//negative regulation of cell growth;GO:2000111//positive regulation of macrophage apoptotic process;GO:0046822//regulation of nucleocytoplasmic transport;GO:2000774//positive regulation of cellular senescence;GO:0031647//regulation of protein stability;GO:0007265//Ras protein signal transduction;GO:0033600//negative regulation of mammary gland epithelial cell proliferation","K06621//cyclin-dependent kinase inhibitor 2A","NP_000068.1//cyclin-dependent kinase inhibitor 2A isoform p16INK4a [Homo sapiens];NP_478104.2//cyclin-dependent kinase inhibitor 2A isoform p12 [Homo sapiens];NP_001182061.1//cyclin-dependent kinase inhibitor 2A isoform p16gamma [Homo sapiens];AAC60649.1//tumor supressor, partial [Homo sapiens]","4;1//3;3//A2MP1"]
[388646,2454,0.01,0.07,2.8073549220576,0.3943649476082,"*",0.249274,"GBP7","NA","NA","NA","K20899//guanylate-binding protein 1/3/4/7","XP_011741466.1//PREDICTED: guanylate-binding protein 7 [Macaca nemestrina]","2//1"]
[26584,1227,0.01,0.07,2.8073549220576,0.649359495601173,"*",0.499032,"DUX1","NA","NA","NA","K18490//homeobox protein OTX2;K09381//paired box protein 3/7;K09332//retina and anterior neural fold homeobox protein","BAA07227.1//facioscapulohumeral muscular dystrophy [Homo sapiens]","1//3"]
[83888,1188,0.01,0.07,2.8073549220576,0.649306603241834,"*",0.499032,"FGFBP2","GO:0005615//extracellular space","GO:0019838//growth factor binding","NA","NA","NP_114156.1//fibroblast growth factor-binding protein 2 precursor [Homo sapiens]","3//A2MP1"]
[1036,1220,0.01,0.07,2.8073549220576,0.649095119941373,"*",0.499032,"CDO1","GO:0005829//cytosol","GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0005506//iron ion binding;GO:0017172//cysteine dioxygenase activity;GO:0008198//ferrous iron binding","GO:0007595//lactation;GO:0042412//taurine biosynthetic process;GO:0043200//response to amino acid;GO:0000097//sulfur amino acid biosynthetic process;GO:0051591//response to cAMP;GO:0055114//oxidation-reduction process;GO:0045471//response to ethanol;GO:0006954//inflammatory response;GO:0006534//cysteine metabolic process;GO:0033762//response to glucagon;GO:0019448//L-cysteine catabolic process;GO:0051384//response to glucocorticoid","K00456//cysteine dioxygenase [EC:1.13.11.20]","NP_001792.2//cysteine dioxygenase type 1 isoform 2 [Homo sapiens];NP_001310494.1//cysteine dioxygenase type 1 isoform 1 [Homo sapiens];NP_001310495.1//cysteine dioxygenase type 1 isoform 3 [Homo sapiens]","1//3;2//1"]
[195814,3403,0.01,0.07,2.8073549220576,0.226566598519194,"*",0.1245166,"SDR16C5","GO:0017053//transcriptional repressor complex;GO:0005634//nucleus;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0004745//retinol dehydrogenase activity;GO:0001191//transcriptional repressor activity, RNA polymerase II transcription factor binding;GO:0008134//transcription factor binding;GO:0033613//activating transcription factor binding","GO:0031065//positive regulation of histone deacetylation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0043616//keratinocyte proliferation;GO:0042572//retinol metabolic process;GO:0042574//retinal metabolic process;GO:0035067//negative regulation of histone acetylation","K15734//all-trans-retinol dehydrogenase (NAD+) [EC:1.1.1.105]","NP_620419.2//epidermal retinol dehydrogenase 2 isoform 2 [Homo sapiens];NP_001304978.1//epidermal retinol dehydrogenase 2 isoform 1 [Homo sapiens];NP_001304979.1//epidermal retinol dehydrogenase 2 isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[4063,2280,0.01,0.07,2.8073549220576,0.393313203871987,"*",0.249274,"LY9","GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","NA","GO:0072540//T-helper 17 cell lineage commitment;GO:0007155//cell adhesion;GO:0032740//positive regulation of interleukin-17 production;GO:0045087//innate immune response","K06570//lymphocyte antigen 9","XP_007974657.1//PREDICTED: LOW QUALITY PROTEIN: T-lymphocyte surface antigen Ly-9-like [Chlorocebus sabaeus];NP_001248385.1//T-lymphocyte surface antigen Ly-9 isoform c [Homo sapiens];NP_002339.2//T-lymphocyte surface antigen Ly-9 isoform a precursor [Homo sapiens];NP_001248386.1//T-lymphocyte surface antigen Ly-9 isoform d precursor [Homo sapiens]","1//3;3//A2MP1;2//1"]
[5104,2352,0.01,0.07,2.8073549220576,0.393235520047403,"*",0.249274,"SERPINA5","GO:0036029//protein C inhibitor-KLK3 complex;GO:0016020//membrane;GO:0097181//protein C inhibitor-coagulation factor V complex;GO:0005615//extracellular space;GO:0097183//protein C inhibitor-coagulation factor XI complex;GO:0009897//external side of plasma membrane;GO:0097182//protein C inhibitor-coagulation factor Xa complex;GO:0036027//protein C inhibitor-PLAU complex;GO:0005576//extracellular region;GO:0036024//protein C inhibitor-TMPRSS7 complex;GO:0002080//acrosomal membrane;GO:0036025//protein C inhibitor-TMPRSS11E complex;GO:0070062//extracellular exosome;GO:0036026//protein C inhibitor-PLAT complex;GO:0036030//protein C inhibitor-plasma kallikrein complex;GO:0031091//platelet alpha granule;GO:0043234//protein complex;GO:0036028//protein C inhibitor-thrombin complex;GO:0031094//platelet dense tubular network","GO:0002020//protease binding;GO:0032190//acrosin binding;GO:0031210//phosphatidylcholine binding;GO:0008233//peptidase activity;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005539//glycosaminoglycan binding;GO:0008201//heparin binding;GO:0001972//retinoic acid binding","GO:0061107//seminal vesicle development;GO:0007596//blood coagulation;GO:0006869//lipid transport;GO:0007342//fusion of sperm to egg plasma membrane involved in single fertilization;GO:0007283//spermatogenesis;GO:0051346//negative regulation of hydrolase activity","K03913//protein C inhibitor","NP_000615.3//plasma serine protease inhibitor preproprotein [Homo sapiens]",5]
[283385,1172,0.01,0.07,2.8073549220576,0.646358320603259,"*",0.499032,"MORN3","GO:0005634//nucleus","NA","NA","K19755//radial spoke head protein 1;K04575//amyotrophic lateral sclerosis 2 protein","XP_008003191.1//PREDICTED: MORN repeat-containing protein 3 isoform X1 [Chlorocebus sabaeus]",4]
[140700,2196,0.01,0.07,2.8073549220576,0.392925091375567,"*",0.249274,"SAMD10","NA","NA","NA","K03129//transcription initiation factor TFIID subunit 4;K19720//collagen, type III, alpha","XP_019492756.1//PREDICTED: zinc finger protein 512B isoform X9 [Hipposideros armiger]",4]
[401124,3210,0.01,0.07,2.8073549220576,0.226334566272189,"*",0.1245166,"DTHD1","NA","NA","GO:0007165//signal transduction","K10130//leucine-rich repeats and death domain-containing protein","XP_006714077.1//PREDICTED: death domain-containing protein 1 isoform X2 [Homo sapiens];NP_001130008.2//death domain-containing protein 1 isoform 2 [Homo sapiens]","4;2//1"]
[79626,1199,0.01,0.07,2.8073549220576,0.644060529045811,"*",0.499032,"TNFAIP8L2","GO:0005737//cytoplasm","NA","GO:0050868//negative regulation of T cell activation;GO:0042981//regulation of apoptotic process;GO:0050728//negative regulation of inflammatory response;GO:0045087//innate immune response","K12471//epsin","XP_008982578.1//PREDICTED: tumor necrosis factor alpha-induced protein 8-like protein 2 isoform X1 [Callithrix jacchus]",4]
[8433,1157,0.01,0.07,2.8073549220576,0.643748459016393,"*",0.499032,"UTF1","GO:0005634//nucleus","GO:0071837//HMG box domain binding;GO:0003713//transcription coactivator activity","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0008584//male gonad development","K16628//collagen, type VII, alpha","AAT38949.1//ES protein, partial [Homo sapiens]","2//1"]
[149628,2038,0.01,0.07,2.8073549220576,0.643540580285783,"*",0.499032,"PYHIN1","GO:0043234//protein complex;GO:0016607//nuclear speck","GO:0031625//ubiquitin protein ligase binding","GO:1902164//positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator;GO:1900182//positive regulation of protein localization to nucleus;GO:0045893//positive regulation of transcription, DNA-templated;GO:2000060//positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0050821//protein stabilization;GO:0007049//cell cycle;GO:0035457//cellular response to interferon-alpha;GO:0031648//protein destabilization;GO:0043388//positive regulation of DNA binding","K20914//gamma-interferon-inducible protein 16","XP_011834051.1//PREDICTED: pyrin and HIN domain-containing protein 1 isoform X3 [Mandrillus leucophaeus];XP_002810006.1//PREDICTED: pyrin and HIN domain-containing protein 1 isoform X1 [Pongo abelii];XP_525227.5//PREDICTED: pyrin and HIN domain-containing protein 1 isoform X3 [Pan troglodytes];NP_945147.1//pyrin and HIN domain-containing protein 1 isoform beta 1 [Homo sapiens]","4;3//A2MP1"]
[27295,2709,0.01,0.07,2.8073549220576,0.392305702068966,"*",0.249274,"PDLIM3","GO:0030018//Z disc;GO:0005829//cytosol;GO:0015629//actin cytoskeleton","GO:0046872//metal ion binding;GO:0008092//cytoskeletal protein binding;GO:0008307//structural constituent of muscle","GO:0007015//actin filament organization;GO:0007507//heart development","K19867//LIM domain-binding protein 3","NP_001107579.1//PDZ and LIM domain protein 3 isoform b [Homo sapiens];NP_001244891.1//PDZ and LIM domain protein 3 isoform c [Homo sapiens];NP_055291.2//PDZ and LIM domain protein 3 isoform a [Homo sapiens];NP_001244892.1//PDZ and LIM domain protein 3 isoform d [Homo sapiens]","4;1//3;5"]
[653689,1108,0.01,0.07,2.8073549220576,0.643280920593932,"*",0.499032,"GSTT2B","GO:0070062//extracellular exosome;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0004364//glutathione transferase activity;GO:0016740//transferase activity","GO:0006749//glutathione metabolic process;GO:1901687//glutathione derivative biosynthetic process","K00799//glutathione S-transferase [EC:2.5.1.18]","NP_001074312.1//glutathione S-transferase theta-2B [Homo sapiens]","3//A2MP1"]
[153328,2217,0.01,0.07,2.8073549220576,0.641262743785697,"*",0.499032,"SLC25A48","GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion","GO:0022857//transmembrane transporter activity","GO:0055085//transmembrane transport;GO:0006839//mitochondrial transport","K15124//solute carrier family 25, member 48","EAW62206.1//similar to CG4995 gene product, isoform CRA_b, partial [Homo sapiens];NP_001336265.1//solute carrier family 25 member 48 isoform 1 [Homo sapiens];XP_016864580.1//PREDICTED: solute carrier family 25 member 48 isoform X9 [Homo sapiens]","4;1//3"]
[339977,3409,0.01,0.07,2.8073549220576,0.226128714006367,"*",0.1245166,"LRRC66","GO:0016021//integral component of membrane;GO:0005737//cytoplasm","GO:0004860//protein kinase inhibitor activity","GO:0006469//negative regulation of protein kinase activity;GO:0046426//negative regulation of JAK-STAT cascade;GO:0019221//cytokine-mediated signaling pathway","K16358//leucine-rich repeat and fibronectin type-III domain-containing protein 5;K13023//carboxypeptidase N regulatory subunit","NP_001019782.1//leucine-rich repeat-containing protein 66 [Homo sapiens]","2//1"]
[27231,1142,0.01,0.07,2.8073549220576,0.639359734359962,"*",0.499032,"NMRK2","GO:0043231//intracellular membrane-bounded organelle;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0046872//metal ion binding;GO:0061769//ribosylnicotinate kinase activity;GO:0005524//ATP binding;GO:0050262//ribosylnicotinamide kinase activity","GO:0045662//negative regulation of myoblast differentiation;GO:0019674//NAD metabolic process;GO:0009435//NAD biosynthetic process","K10524//nicotinamide/nicotinate riboside kinase [EC:2.7.1.22 2.7.1.173]","NP_001276046.1//nicotinamide riboside kinase 2 isoform 1 [Homo sapiens];NP_733778.1//nicotinamide riboside kinase 2 isoform 2 [Homo sapiens]","1//3;2//1"]
[729665,2610,0.03,0.21,2.8073549220576,0.0851514956712931,"*",0.038791,"CCDC175","NA","NA","NA","K20721//reticulon-1;K20478//golgin subfamily B member 1","NP_001157871.1//coiled-coil domain-containing protein 175 [Homo sapiens]","1//3"]
[23780,2560,10.58,73,2.78655683654072,0,"Up",0,"APOL2","GO:0016021//integral component of membrane;GO:0005576//extracellular region","GO:0008289//lipid binding","GO:0006869//lipid transport;GO:0042157//lipoprotein metabolic process","K14480//apolipoprotein L","BAD92227.1//apolipoprotein L2 variant, partial [Homo sapiens]","3//A2MP1;2//1"]
[51676,2781,0.06,0.4,2.73696559416621,0.00696574494736842,"*",0.00231988,"ASB2","GO:0000151//ubiquitin ligase complex;GO:0005829//cytosol;GO:0031466//Cul5-RING ubiquitin ligase complex","GO:0061630//ubiquitin protein ligase activity","GO:0043687//post-translational protein modification;GO:0007165//signal transduction;GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0045445//myoblast differentiation;GO:0035914//skeletal muscle cell differentiation;GO:0000209//protein polyubiquitination","K10324//ankyrin repeat and SOCS box protein 2","XP_012353411.1//PREDICTED: ankyrin repeat and SOCS box protein 2 isoform X2 [Nomascus leucogenys];NP_001189358.1//ankyrin repeat and SOCS box protein 2 isoform 1 [Homo sapiens]","1//3;4"]
[80231,1927,0.06,0.4,2.73696559416621,0.0295022939863253,"*",0.01161512,"CXorf21","NA","NA","NA","K06689//ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23];K22069//LYR motif-containing protein 4;K12581//CCR4-NOT transcription complex subunit 7/8;K01368//cathepsin S [EC:3.4.22.27]","NP_079435.1//uncharacterized protein CXorf21 [Homo sapiens]","2//1"]
[6737,1946,11.97,77.97,2.70349598224985,{"v":1.13469899529412e-284,"d":"1.13E-284"},"Up",{"v":1.20758E-287,"d":"1.21E-287"},"TRIM21","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031410//cytoplasmic vesicle;GO:0000932//P-body;GO:0005737//cytoplasm;GO:0019005//SCF ubiquitin ligase complex;GO:0005829//cytosol;GO:0030529//intracellular ribonucleoprotein complex;GO:0005776//autophagosome","GO:0003723//RNA binding;GO:0003677//DNA binding;GO:0042802//identical protein binding;GO:0008270//zinc ion binding;GO:0004842//ubiquitin-protein transferase activity","GO:0032479//regulation of type I interferon production;GO:0070206//protein trimerization;GO:0016567//protein ubiquitination;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0034341//response to interferon-gamma;GO:0051865//protein autoubiquitination;GO:0032897//negative regulation of viral transcription;GO:0031648//protein destabilization;GO:0045087//innate immune response;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0000209//protein polyubiquitination;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0090086//negative regulation of protein deubiquitination;GO:0006513//protein monoubiquitination;GO:1902187//negative regulation of viral release from host cell;GO:0010508//positive regulation of autophagy;GO:0046598//positive regulation of viral entry into host cell;GO:0007049//cell cycle;GO:0045787//positive regulation of cell cycle","K10651//tripartite motif-containing protein 21 [EC:2.3.2.27]","NP_003132.2//E3 ubiquitin-protein ligase TRIM21 [Homo sapiens]","3//A2MP1"]
[80830,10156,1.59,10.34,2.70113751503058,{"v":1.8403046375e-201,"d":"1.84E-201"},"Up",{"v":3.6866e-204,"d":"3.69E-204"},"APOL6","GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0008289//lipid binding","GO:0006869//lipid transport;GO:0042157//lipoprotein metabolic process","K14480//apolipoprotein L","NP_085144.1//apolipoprotein L6 [Homo sapiens]","3//A2MP1"]
[3437,2498,2.46,15.6,2.66481580841037,{"v":2.65049469489051e-72,"d":"2.65E-72"},"Up",{"v":2.27318e-74,"d":"2.27E-74"},"IFIT3","GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005737//cytoplasm","GO:0042802//identical protein binding","GO:0060337//type I interferon signaling pathway;GO:0051607//defense response to virus;GO:0043066//negative regulation of apoptotic process;GO:0045087//innate immune response;GO:0009615//response to virus;GO:0035457//cellular response to interferon-alpha;GO:0008285//negative regulation of cell proliferation","K14217//interferon-induced protein with tetratricopeptide repeats 1","NP_001540.2//interferon-induced protein with tetratricopeptide repeats 3 isoform a [Homo sapiens]","1//3;3//A2MP1;5"]
[3852,2320,0.38,2.4,2.65896308216493,{"v":1.11281480873362e-10,"d":"1.11E-10"},"Up",{"v":1.116716e-11,"d":"1.12E-11"},"KRT5","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005882//intermediate filament;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0045095//keratin filament;GO:0005739//mitochondrion;GO:0005886//plasma membrane","GO:0097110//scaffold protein binding;GO:0005198//structural molecule activity;GO:0005200//structural constituent of cytoskeleton","GO:0008544//epidermis development;GO:0031424//keratinization;GO:0031581//hemidesmosome assembly;GO:0070268//cornification","K07605//type II keratin, basic","NP_000415.2//keratin, type II cytoskeletal 5 [Homo sapiens]","3//A2MP1"]
[89870,2241,0.04,0.25,2.64385618977472,0.0851749050171821,"*",0.038791,"TRIM15","GO:0005622//intracellular","GO:0008270//zinc ion binding","GO:0032481//positive regulation of type I interferon production;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:1901253//negative regulation of intracellular transport of viral material;GO:1900246//positive regulation of RIG-I signaling pathway;GO:1902187//negative regulation of viral release from host cell;GO:0007500//mesodermal cell fate determination;GO:0045087//innate immune response","K12005//tripartite motif-containing protein 15","NP_150232.2//tripartite motif-containing protein 15 [Homo sapiens]","2//1"]
[644538,1552,0.05,0.31,2.63226821549951,0.140042607275464,"*",0.0698898,"SMIM10","NA","NA","NA","NA","AAH08642.1//LOC644538 protein, partial [Homo sapiens]","1//3"]
[25818,1398,0.01,0.06,2.58496250072116,0.655554043421053,"*",0.499032,"KLK5","GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005576//extracellular region;GO:0097209//epidermal lamellar body","GO:0004252//serine-type endopeptidase activity;GO:0004175//endopeptidase activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity","GO:0045745//positive regulation of G-protein coupled receptor protein signaling pathway;GO:0008544//epidermis development;GO:0002803//positive regulation of antibacterial peptide production;GO:0070268//cornification","K09617//kallikrein 5 [EC:3.4.21.-]","NP_036559.1//kallikrein-5 preproprotein [Homo sapiens]","1//3;4"]
[2837,1310,0.01,0.06,2.58496250072116,0.655069206015285,"*",0.499032,"UTS2R","GO:0016020//membrane;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0055037//recycling endosome;GO:0005886//plasma membrane;GO:0005769//early endosome","GO:0001604//urotensin II receptor activity;GO:0004930//G-protein coupled receptor activity","GO:0008217//regulation of blood pressure;GO:0010841//positive regulation of circadian sleep/wake cycle, wakefulness;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0045777//positive regulation of blood pressure;GO:0030307//positive regulation of cell growth;GO:0045776//negative regulation of blood pressure;GO:0045907//positive regulation of vasoconstriction;GO:0046005//positive regulation of circadian sleep/wake cycle, REM sleep;GO:0007218//neuropeptide signaling pathway;GO:0045766//positive regulation of angiogenesis;GO:0097746//regulation of blood vessel diameter;GO:0042493//response to drug;GO:0003105//negative regulation of glomerular filtration;GO:0035814//negative regulation of renal sodium excretion;GO:0007165//signal transduction;GO:0048146//positive regulation of fibroblast proliferation;GO:0008015//blood circulation;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0035811//negative regulation of urine volume","K04241//urotensin 2 receptor","NP_061822.1//urotensin-2 receptor [Homo sapiens]","2//1"]
[2532,1258,0.01,0.06,2.58496250072116,0.655015379457683,"*",0.499032,"ACKR1","GO:0016021//integral component of membrane;GO:0055037//recycling endosome;GO:0005886//plasma membrane;GO:0005769//early endosome","GO:0004872//receptor activity;GO:0019956//chemokine binding;GO:0004888//transmembrane signaling receptor activity;GO:0019957//C-C chemokine binding;GO:0004930//G-protein coupled receptor activity","GO:0006952//defense response;GO:0070098//chemokine-mediated signaling pathway;GO:0032642//regulation of chemokine production;GO:0006954//inflammatory response","K06574//Duffy blood group glycoprotein","NP_001116423.1//atypical chemokine receptor 1 isoform a [Homo sapiens];NP_002027.2//atypical chemokine receptor 1 isoform b [Homo sapiens]","3//A2MP1;2//1"]
[680,1413,0.01,0.06,2.58496250072116,0.654262735390676,"*",0.499032,"BRS3","GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0043025//neuronal cell body;GO:0043005//neuron projection","GO:0004946//bombesin receptor activity","GO:0008217//regulation of blood pressure;GO:0006006//glucose metabolic process;GO:0008343//adult feeding behavior","K04170//bombesin-like receptor 3","NP_001718.1//bombesin receptor subtype-3 [Homo sapiens]","1//3"]
[26291,1333,0.01,0.06,2.58496250072116,0.653833429133858,"*",0.499032,"FGF21","GO:0005615//extracellular space;GO:0005623//cell;GO:0005576//extracellular region","GO:0008083//growth factor activity;GO:0005104//fibroblast growth factor receptor binding","GO:0090080//positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway;GO:1901215//negative regulation of neuron death;GO:0010898//positive regulation of triglyceride catabolic process;GO:0071404//cellular response to low-density lipoprotein particle stimulus;GO:0035690//cellular response to drug;GO:0010988//regulation of low-density lipoprotein particle clearance;GO:0046326//positive regulation of glucose import;GO:0045716//positive regulation of low-density lipoprotein particle receptor biosynthetic process;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0030968//endoplasmic reticulum unfolded protein response;GO:1904640//response to methionine;GO:0071377//cellular response to glucagon stimulus;GO:0007165//signal transduction;GO:0014823//response to activity;GO:0007267//cell-cell signaling;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:0071333//cellular response to glucose stimulus;GO:0031667//response to nutrient levels;GO:0072577//endothelial cell apoptotic process;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0008284//positive regulation of cell proliferation","K04358//fibroblast growth factor","NP_061986.1//fibroblast growth factor 21 precursor [Homo sapiens]","3//A2MP1"]
[3595,3782,0.01,0.06,2.58496250072116,0.395186867407701,"*",0.249274,"IL12RB2","GO:0016020//membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004896//cytokine receptor activity;GO:0019901//protein kinase binding","GO:0032496//response to lipopolysaccharide;GO:0007166//cell surface receptor signaling pathway;GO:0032609//interferon-gamma production;GO:0032729//positive regulation of interferon-gamma production;GO:0008284//positive regulation of cell proliferation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0035722//interleukin-12-mediated signaling pathway","K05064//interleukin 12 receptor beta-2","NP_001245144.1//interleukin-12 receptor subunit beta-2 isoform c precursor [Homo sapiens];NP_001245145.1//interleukin-12 receptor subunit beta-2 isoform d precursor [Homo sapiens];NP_001245143.1//interleukin-12 receptor subunit beta-2 isoform b precursor [Homo sapiens];AAI04773.1//Interleukin 12 receptor, beta 2, precursor [Homo sapiens]","1//3;2//1"]
[1959,2855,0.03,0.18,2.58496250072116,0.140060176289048,"*",0.0698898,"EGR2","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm","GO:0071837//HMG box domain binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0031625//ubiquitin protein ligase binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0016874//ligase activity;GO:0046872//metal ion binding;GO:0003682//chromatin binding;GO:0001102//RNA polymerase II activating transcription factor binding;GO:0003700//DNA binding transcription factor activity","GO:0021612//facial nerve structural organization;GO:0016925//protein sumoylation;GO:0021666//rhombomere 5 formation;GO:0007420//brain development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0071310//cellular response to organic substance;GO:0014037//Schwann cell differentiation;GO:0048168//regulation of neuronal synaptic plasticity;GO:0006611//protein export from nucleus;GO:0007611//learning or memory;GO:0007622//rhythmic behavior;GO:0042552//myelination;GO:0008045//motor neuron axon guidance;GO:0032868//response to insulin;GO:0035284//brain segmentation;GO:0021660//rhombomere 3 formation;GO:0006366//transcription from RNA polymerase II promoter;GO:0030278//regulation of ossification;GO:0035914//skeletal muscle cell differentiation;GO:0045444//fat cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007422//peripheral nervous system development","K12496//early growth response protein 2","NP_000390.2//E3 SUMO-protein ligase EGR2 isoform a [Homo sapiens];XP_011537729.1//PREDICTED: E3 SUMO-protein ligase EGR2 isoform X1 [Homo sapiens]","4;1//3;2//1"]
[125972,1295,0.01,0.06,2.58496250072116,0.65335113253012,"*",0.499032,"CALR3","GO:0005788//endoplasmic reticulum lumen;GO:0005783//endoplasmic reticulum","GO:0030246//carbohydrate binding;GO:0051082//unfolded protein binding;GO:0005509//calcium ion binding;GO:0044183//protein binding involved in protein folding","GO:0030154//cell differentiation;GO:0007283//spermatogenesis","K10098//calreticulin 3","NP_659483.2//calreticulin-3 precursor [Homo sapiens]",4]
[7018,3511,0.01,0.06,2.58496250072116,0.395147650689689,"*",0.249274,"TF","GO:0034774//secretory granule lumen;GO:1990712//HFE-transferrin receptor complex;GO:0010008//endosome membrane;GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0005770//late endosome;GO:0016324//apical plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0031232//extrinsic component of external side of plasma membrane;GO:0031982//vesicle;GO:0097433//dense body;GO:0030120//vesicle coat;GO:0005623//cell;GO:0005576//extracellular region;GO:0030665//clathrin-coated vesicle membrane;GO:0055037//recycling endosome;GO:0005769//early endosome;GO:0070062//extracellular exosome;GO:0072562//blood microparticle;GO:0048471//perinuclear region of cytoplasm;GO:0009925//basal plasma membrane;GO:0009986//cell surface;GO:0030139//endocytic vesicle;GO:0005905//clathrin-coated pit;GO:0045178//basal part of cell","GO:0015091//ferric iron transmembrane transporter activity;GO:0008199//ferric iron binding;GO:1990459//transferrin receptor binding;GO:0008198//ferrous iron binding","GO:0043687//post-translational protein modification;GO:0006879//cellular iron ion homeostasis;GO:0001895//retina homeostasis;GO:0098707//ferrous iron import across plasma membrane;GO:0061024//membrane organization;GO:0071281//cellular response to iron ion;GO:0044267//cellular protein metabolic process;GO:0055072//iron ion homeostasis;GO:0002576//platelet degranulation;GO:0031647//regulation of protein stability;GO:0033572//transferrin transport;GO:0048260//positive regulation of receptor-mediated endocytosis","K14736//transferrin","NP_001341632.1//serotransferrin isoform 2 [Homo sapiens];NP_001054.1//serotransferrin isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[196374,2572,0.01,0.06,2.58496250072116,0.395069240599266,"*",0.249274,"KRT78","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0045095//keratin filament","GO:0005198//structural molecule activity","GO:0031424//keratinization;GO:0070268//cornification","K07605//type II keratin, basic","NP_001287743.1//keratin, type II cytoskeletal 78 isoform 2 [Homo sapiens];NP_775487.2//keratin, type II cytoskeletal 78 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[284348,2519,0.01,0.06,2.58496250072116,0.394599432761867,"*",0.249274,"LYPD5","GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0031225//anchored component of membrane","GO:0043236//laminin binding","GO:0007160//cell-matrix adhesion;GO:0006501//C-terminal protein lipidation","K06824//nephronectin","NP_001026919.2//ly6/PLAUR domain-containing protein 5 isoform A precursor [Homo sapiens];XP_016791582.1//PREDICTED: ly6/PLAUR domain-containing protein 5 isoform X1 [Pan troglodytes]","1//3;2//1"]
[6754,1258,0.01,0.06,2.58496250072116,0.651162977291292,"*",0.499032,"SSTR4","GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0043005//neuron projection","GO:0042923//neuropeptide binding;GO:0004994//somatostatin receptor activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0016477//cell migration;GO:0019369//arachidonic acid metabolic process;GO:0030815//negative regulation of cAMP metabolic process;GO:0071385//cellular response to glucocorticoid stimulus;GO:0030900//forebrain development;GO:0043410//positive regulation of MAPK cascade;GO:0007268//chemical synaptic transmission;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0008285//negative regulation of cell proliferation","K04220//somatostatin receptor 4","NP_001043.2//somatostatin receptor type 4 [Homo sapiens]","2//1"]
[29103,2792,0.01,0.06,2.58496250072116,0.394443078355622,"*",0.249274,"DNAJC15","GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane","NA","GO:0009267//cellular response to starvation;GO:0019216//regulation of lipid metabolic process;GO:1902957//negative regulation of mitochondrial electron transport, NADH to ubiquinone;GO:0015031//protein transport;GO:0031333//negative regulation of protein complex assembly","K09535//DnaJ homolog subfamily C member 15","NP_037370.2//dnaJ homolog subfamily C member 15 [Homo sapiens]","2//1"]
[5676,1680,0.01,0.06,2.58496250072116,0.650790853783982,"*",0.499032,"PSG7","GO:0005576//extracellular region","NA","GO:0007565//female pregnancy","K06500//pregnancy specific beta-1-glycoprotein","NP_001193579.1//putative pregnancy-specific beta-1-glycoprotein 7 isoform 2 [Homo sapiens];XP_016789756.1//PREDICTED: putative pregnancy-specific beta-1-glycoprotein 7 [Pan troglodytes]","1//3;2//1"]
[10205,2791,0.01,0.06,2.58496250072116,0.65063150244858,"*",0.499032,"MPZL2","GO:0005856//cytoskeleton;GO:0016021//integral component of membrane","NA","GO:0009653//anatomical structure morphogenesis;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules","K06770//myelin protein zero","NP_005788.1//myelin protein zero-like protein 2 precursor [Homo sapiens]","3//A2MP1;2//1"]
[23493,2672,0.01,0.06,2.58496250072116,0.394208778932779,"*",0.249274,"HEY2","GO:0017053//transcriptional repressor complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016580//Sin3 complex;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0042826//histone deacetylase binding;GO:0046982//protein heterodimerization activity;GO:0000983//transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding;GO:0042803//protein homodimerization activity;GO:0046983//protein dimerization activity;GO:0035939//microsatellite binding;GO:0000988//transcription factor activity, protein binding;GO:0003700//DNA binding transcription factor activity;GO:0001102//RNA polymerase II activating transcription factor binding","GO:0003195//tricuspid valve formation;GO:0010667//negative regulation of cardiac muscle cell apoptotic process;GO:0014031//mesenchymal cell development;GO:0060948//cardiac vascular smooth muscle cell development;GO:0060977//coronary vasculature morphogenesis;GO:0001570//vasculogenesis;GO:0036304//umbilical cord morphogenesis;GO:0003215//cardiac right ventricle morphogenesis;GO:0060842//arterial endothelial cell differentiation;GO:0035912//dorsal aorta morphogenesis;GO:0003151//outflow tract morphogenesis;GO:0003150//muscular septum morphogenesis;GO:2001212//regulation of vasculogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045607//regulation of inner ear auditory receptor cell differentiation;GO:0007219//Notch signaling pathway;GO:0003222//ventricular trabecula myocardium morphogenesis;GO:0097084//vascular smooth muscle cell development;GO:0055015//ventricular cardiac muscle cell development;GO:2000678//negative regulation of transcription regulatory region DNA binding;GO:0006355//regulation of transcription, DNA-templated;GO:0014898//cardiac muscle hypertrophy in response to stress;GO:0060633//negative regulation of transcription initiation from RNA polymerase II promoter;GO:0061156//pulmonary artery morphogenesis;GO:0003184//pulmonary valve morphogenesis;GO:0003199//endocardial cushion to mesenchymal transition involved in heart valve formation;GO:0003214//cardiac left ventricle morphogenesis;GO:0035910//ascending aorta morphogenesis;GO:0045165//cell fate commitment;GO:0065004//protein-DNA complex assembly;GO:0010460//positive regulation of heart rate;GO:0060716//labyrinthine layer blood vessel development;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0006351//transcription, DNA-templated;GO:0060413//atrial septum morphogenesis;GO:0060347//heart trabecula formation;GO:0045746//negative regulation of Notch signaling pathway;GO:2000820//negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation;GO:0090102//cochlea development;GO:0009948//anterior/posterior axis specification","K09091//hairy and enhancer of split related with YRPW motif","NP_036391.1//hairy/enhancer-of-split related with YRPW motif protein 2 [Homo sapiens]","2//1"]
[728957,3683,0.01,0.06,2.58496250072116,0.226773249162011,"*",0.1245166,"ZNF705D","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_004452775.1//PREDICTED: zinc finger protein 596-like isoform X1 [Dasypus novemcinctus]","3//A2MP1"]
[3240,1301,0.01,0.06,2.58496250072116,0.650100894470723,"*",0.499032,"HP","GO:1904724//tertiary granule lumen;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0072562//blood microparticle;GO:0035580//specific granule lumen;GO:0031838//haptoglobin-hemoglobin complex;GO:0005576//extracellular region;GO:0071682//endocytic vesicle lumen","GO:0004252//serine-type endopeptidase activity;GO:0016209//antioxidant activity;GO:0030492//hemoglobin binding","GO:0006953//acute-phase response;GO:0051354//negative regulation of oxidoreductase activity;GO:0042742//defense response to bacterium;GO:0042542//response to hydrogen peroxide;GO:0006952//defense response;GO:0006898//receptor-mediated endocytosis;GO:0043312//neutrophil degranulation;GO:2000296//negative regulation of hydrogen peroxide catabolic process;GO:0010942//positive regulation of cell death","K16142//haptoglobin","EAW59197.1//haptoglobin, isoform CRA_d [Homo sapiens];EAW59194.1//haptoglobin, isoform CRA_a [Homo sapiens]","4;1//3;2//1"]
[28999,2539,0.01,0.06,2.58496250072116,0.394091733570863,"*",0.249274,"KLF15","NA","NA","NA","K09210//krueppel-like factor 15","XP_011511045.1//PREDICTED: Krueppel-like factor 15 isoform X1 [Homo sapiens]","3//A2MP1"]
[10017,1255,0.01,0.06,2.58496250072116,0.649941880799022,"*",0.499032,"BCL2L10","GO:0016020//membrane;GO:0031965//nuclear membrane;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane","GO:0089720//caspase binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity","GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0007283//spermatogenesis;GO:0007292//female gamete generation;GO:0043065//positive regulation of apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process","K18451//Bcl-2-like protein 10","NP_065129.1//bcl-2-like protein 10 isoform 2 [Homo sapiens];NP_001293097.1//bcl-2-like protein 10 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[9413,2138,0.01,0.06,2.58496250072116,0.394013741935484,"*",0.249274,"FAM189A2","NA","NA","NA","K02893//large subunit ribosomal protein L23Ae;K01201//glucosylceramidase [EC:3.2.1.45];K13751//solute carrier family 24 (sodium/potassium/calcium exchanger), member 3","NP_001334924.1//protein FAM189A2 isoform a [Homo sapiens]","1//3;4;2//1"]
[9823,2853,0.01,0.06,2.58496250072116,0.393779952136076,"*",0.249274,"ARMCX2","GO:0016021//integral component of membrane","NA","NA","K20493//leucine-rich repeat-containing protein 16","XP_007990504.1//PREDICTED: LOW QUALITY PROTEIN: armadillo repeat-containing X-linked protein 2 [Chlorocebus sabaeus]","6;1//3;3//A2MP1"]
[11314,1456,0.01,0.06,2.58496250072116,0.648197850707432,"*",0.499032,"CD300A","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0101003//ficolin-1-rich granule membrane;GO:0016021//integral component of membrane;GO:0070821//tertiary granule membrane;GO:0005886//plasma membrane","GO:0038023//signaling receptor activity;GO:0008429//phosphatidylethanolamine binding;GO:0001786//phosphatidylserine binding","GO:1902567//negative regulation of eosinophil activation;GO:0043407//negative regulation of MAP kinase activity;GO:0060101//negative regulation of phagocytosis, engulfment;GO:0043305//negative regulation of mast cell degranulation;GO:0051134//negative regulation of NK T cell activation;GO:0043312//neutrophil degranulation;GO:0050776//regulation of immune response;GO:0033007//negative regulation of mast cell activation involved in immune response;GO:2000417//negative regulation of eosinophil migration;GO:0032516//positive regulation of phosphoprotein phosphatase activity;GO:0048147//negative regulation of fibroblast proliferation;GO:0050856//regulation of T cell receptor signaling pathway;GO:1902564//negative regulation of neutrophil activation;GO:1902569//negative regulation of activation of Janus kinase activity;GO:0007155//cell adhesion;GO:0050859//negative regulation of B cell receptor signaling pathway;GO:0030889//negative regulation of B cell proliferation;GO:0034125//negative regulation of MyD88-dependent toll-like receptor signaling pathway","K06719//CD300 antigen","NP_001317386.1//CMRF35-like molecule 8 isoform 4 precursor [Homo sapiens];NP_009192.2//CMRF35-like molecule 8 isoform 1 precursor [Homo sapiens];NP_001243770.1//CMRF35-like molecule 8 isoform 2 precursor [Homo sapiens]","1//3;3//A2MP1"]
[29015,2650,0.01,0.06,2.58496250072116,0.392963868153558,"*",0.249274,"SLC43A3","GO:0016021//integral component of membrane","NA","GO:0055085//transmembrane transport","K08230//MFS transporter, LAT3 family, solute carrier family 43, member 3","NP_060081.1//solute carrier family 43 member 3 isoform 1 [Homo sapiens];XP_008950090.1//PREDICTED: solute carrier family 43 member 3 isoform X1 [Pan paniscus];XP_008950091.1//PREDICTED: solute carrier family 43 member 3 isoform X2 [Pan paniscus]","1//3;3//A2MP1;2//1"]
[7148,6237,0.05,0.3,2.58496250072116,0.0185247834046136,"*",0.00688736,"TNXB","GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005622//intracellular;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix","GO:0005201//extracellular matrix structural constituent;GO:0005178//integrin binding;GO:0008201//heparin binding","GO:0032963//collagen metabolic process;GO:0007155//cell adhesion;GO:0030036//actin cytoskeleton organization;GO:0030199//collagen fibril organization;GO:0048251//elastic fiber assembly","K06252//tenascin","NP_061978.6//tenascin-X isoform 1 precursor [Homo sapiens]","6;3//A2MP1"]
[121506,1388,0.01,0.06,2.58496250072116,0.645207379036827,"*",0.499032,"ERP27","GO:0005788//endoplasmic reticulum lumen","NA","NA","K20355//endoplasmic reticulum protein 27","XP_012357838.1//PREDICTED: endoplasmic reticulum resident protein 27 isoform X2 [Nomascus leucogenys];NP_689534.1//endoplasmic reticulum resident protein 27 isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[5449,1262,0.01,0.06,2.58496250072116,0.64473771983177,"*",0.499032,"POU1F1","GO:0005634//nucleus;GO:0005667//transcription factor complex","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003714//transcription corepressor activity;GO:0001105//RNA polymerase II transcription coactivator activity;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0003682//chromatin binding;GO:0043565//sequence-specific DNA binding;GO:0001102//RNA polymerase II activating transcription factor binding;GO:0003700//DNA binding transcription factor activity","GO:0006355//regulation of transcription, DNA-templated;GO:0043567//regulation of insulin-like growth factor receptor signaling pathway;GO:0006351//transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0060133//somatotropin secreting cell development;GO:0008340//determination of adult lifespan;GO:0051169//nuclear transport;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0001708//cell fate specification;GO:0032962//positive regulation of inositol trisphosphate biosynthetic process;GO:0040018//positive regulation of multicellular organism growth;GO:0030183//B cell differentiation;GO:0008285//negative regulation of cell proliferation;GO:0008284//positive regulation of cell proliferation","K09363//POU domain transcription factor, class 1","NP_000297.1//pituitary-specific positive transcription factor 1 isoform alpha [Homo sapiens];NP_001116229.1//pituitary-specific positive transcription factor 1 isoform beta [Homo sapiens]","3//A2MP1;2//1"]
[257062,2528,0.01,0.06,2.58496250072116,0.392499051355347,"*",0.249274,"CATSPERD","GO:0097228//sperm principal piece;GO:0005886//plasma membrane;GO:0036128//CatSper complex","NA","GO:0030317//flagellated sperm motility;GO:0035036//sperm-egg recognition;GO:0007275//multicellular organism development;GO:0048240//sperm capacitation;GO:0007283//spermatogenesis;GO:0032570//response to progesterone","K16895//cation channel sperm-associated protein subunit delta","NP_689997.3//cation channel sperm-associated protein subunit delta precursor [Homo sapiens]","3//A2MP1"]
[1187,2555,0.01,0.06,2.58496250072116,0.643800449685027,"*",0.499032,"CLCNKA","GO:0005887//integral component of plasma membrane;GO:0034707//chloride channel complex;GO:0005886//plasma membrane","GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0005247//voltage-gated chloride channel activity","GO:0006810//transport;GO:0034220//ion transmembrane transport;GO:0007588//excretion;GO:1902476//chloride transmembrane transport","K05018//chloride channel Kb","NP_001036169.1//chloride channel protein ClC-Ka isoform 2 [Homo sapiens];NP_001244068.1//chloride channel protein ClC-Ka isoform 3 [Homo sapiens];NP_004061.3//chloride channel protein ClC-Ka isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[9023,1378,0.01,0.06,2.58496250072116,0.643592537380914,"*",0.499032,"CH25H","GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0008395//steroid hydroxylase activity;GO:0005506//iron ion binding;GO:0001567//cholesterol 25-hydroxylase activity;GO:0016491//oxidoreductase activity","GO:0016126//sterol biosynthetic process;GO:0008203//cholesterol metabolic process;GO:0035754//B cell chemotaxis;GO:0008610//lipid biosynthetic process;GO:0006629//lipid metabolic process;GO:0006699//bile acid biosynthetic process","K10223//cholesterol 25-hydroxylase [EC:1.14.99.38]","NP_003947.1//cholesterol 25-hydroxylase [Homo sapiens]","3//A2MP1"]
[3467,1270,0.01,0.06,2.58496250072116,0.643488631578947,"*",0.499032,"IFNW1","GO:0005615//extracellular space","GO:0005132//type I interferon receptor binding;GO:0005125//cytokine activity;GO:0005126//cytokine receptor binding","GO:0051607//defense response to virus;GO:0043330//response to exogenous dsRNA;GO:0007050//cell cycle arrest;GO:0002250//adaptive immune response;GO:0042100//B cell proliferation;GO:0006959//humoral immune response;GO:0002286//T cell activation involved in immune response;GO:0033141//positive regulation of peptidyl-serine phosphorylation of STAT protein;GO:0002323//natural killer cell activation involved in immune response;GO:0030183//B cell differentiation;GO:0019221//cytokine-mediated signaling pathway;GO:0009615//response to virus;GO:0045087//innate immune response","K05440//interferon omega","XP_016816170.1//PREDICTED: interferon omega-1 [Pan troglodytes]","2//1"]
[282890,2517,0.03,0.18,2.58496250072116,0.140007482468021,"*",0.0698898,"ZNF311","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","XP_021571051.1//zinc finger protein 311 [Carlito syrichta];XP_004447449.1//PREDICTED: zinc finger protein 311 isoform X1 [Dasypus novemcinctus]","1//3;3//A2MP1"]
[11126,1633,0.05,0.3,2.58496250072116,0.139989926670846,"*",0.0698898,"CD160","GO:0016021//integral component of membrane;GO:0046658//anchored component of plasma membrane;GO:0005886//plasma membrane","GO:0004872//receptor activity;GO:0032393//MHC class I receptor activity;GO:0005102//receptor binding","GO:0050829//defense response to Gram-negative bacterium;GO:0008283//cell proliferation;GO:0007166//cell surface receptor signaling pathway;GO:0006968//cellular defense response;GO:0050776//regulation of immune response","K06542//CD160 antigen","NP_008984.1//CD160 antigen precursor [Homo sapiens]","3//A2MP1"]
[284366,1438,0.01,0.06,2.58496250072116,0.640284109879518,"*",0.499032,"KLK9","GO:0005576//extracellular region","GO:0004252//serine-type endopeptidase activity","NA","K09618//kallikrein 9 [EC:3.4.21.-]","XP_011936429.1//PREDICTED: kallikrein-9 [Cercocebus atys]","1//3"]
[6364,851,0.49,2.93,2.58004701030704,{"v":5.68831654653465E-5,"d":"5.69E-05"},"Up",{"v":1.258808e-05,"d":"1.26E-05"},"CCL20","GO:0005615//extracellular space;GO:0005622//intracellular;GO:0005576//extracellular region","GO:0048020//CCR chemokine receptor binding;GO:0008009//chemokine activity;GO:0031731//CCR6 chemokine receptor binding","GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0072678//T cell migration;GO:0071222//cellular response to lipopolysaccharide;GO:0043547//positive regulation of GTPase activity;GO:0042742//defense response to bacterium;GO:0071356//cellular response to tumor necrosis factor;GO:0035584//calcium-mediated signaling using intracellular calcium source;GO:0071346//cellular response to interferon-gamma;GO:0051770//positive regulation of nitric-oxide synthase biosynthetic process;GO:0071347//cellular response to interleukin-1;GO:0060326//cell chemotaxis;GO:0002548//monocyte chemotaxis;GO:0006935//chemotaxis;GO:2000406//positive regulation of T cell migration;GO:0050726//positive regulation of interleukin-1 alpha biosynthetic process;GO:0048247//lymphocyte chemotaxis;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007165//signal transduction;GO:0030593//neutrophil chemotaxis;GO:0042060//wound healing;GO:0007267//cell-cell signaling;GO:0071223//cellular response to lipoteichoic acid;GO:0070098//chemokine-mediated signaling pathway;GO:0031640//killing of cells of other organism;GO:0006954//inflammatory response;GO:0072679//thymocyte migration;GO:0006955//immune response;GO:0070374//positive regulation of ERK1 and ERK2 cascade","K14625//C-C motif chemokine 20","NP_001123518.1//C-C motif chemokine 20 isoform 2 precursor [Homo sapiens];NP_004582.1//C-C motif chemokine 20 isoform 1 precursor [Homo sapiens]","1//3;2//1"]
[2634,4148,0.29,1.72,2.56828375957453,{"v":2.23850927511886E-13,"d":"2.24E-13"},"Up",{"v":1.768498E-14,"d":"1.77E-14"},"GBP2","GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0015629//actin cytoskeleton","GO:0005525//GTP binding;GO:0003924//GTPase activity","NA","K20897//guanylate-binding protein 2","XP_007976231.1//PREDICTED: interferon-induced guanylate-binding protein 2 [Chlorocebus sabaeus]",4]
[10379,1699,9.78,57.66,2.55966446654267,{"v":2.94495025641025e-172,"d":"2.94E-172"},"Up",{"v":7.19e-175,"d":"7.19E-175"},"IRF9","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0003700//DNA binding transcription factor activity;GO:0001047//core promoter binding","GO:0060333//interferon-gamma-mediated signaling pathway;GO:0060337//type I interferon signaling pathway;GO:0051607//defense response to virus;GO:0006351//transcription, DNA-templated;GO:0007166//cell surface receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter","K04693//interferon regulatory factor 9","NP_006075.3//interferon regulatory factor 9 [Homo sapiens]",4]
[7098,3057,0.05,0.29,2.53605290024021,0.0321612377117712,"*",0.01281094,"TLR3","GO:0016020//membrane;GO:0005765//lysosomal membrane;GO:0010008//endosome membrane;GO:0005622//intracellular;GO:0036020//endolysosome membrane;GO:0005737//cytoplasm;GO:0000139//Golgi membrane;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005769//early endosome","GO:0004872//receptor activity;GO:0042802//identical protein binding;GO:0004888//transmembrane signaling receptor activity;GO:0003725//double-stranded RNA binding","GO:0046330//positive regulation of JNK cascade;GO:0097191//extrinsic apoptotic signaling pathway;GO:0071260//cellular response to mechanical stimulus;GO:0035690//cellular response to drug;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0097190//apoptotic signaling pathway;GO:0034123//positive regulation of toll-like receptor signaling pathway;GO:0008584//male gonad development;GO:0071346//cellular response to interferon-gamma;GO:0032760//positive regulation of tumor necrosis factor production;GO:0043065//positive regulation of apoptotic process;GO:0035458//cellular response to interferon-beta;GO:0045087//innate immune response;GO:0007165//signal transduction;GO:0032757//positive regulation of interleukin-8 production;GO:0007250//activation of NF-kappaB-inducing kinase activity;GO:0010628//positive regulation of gene expression;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045671//negative regulation of osteoclast differentiation;GO:0032755//positive regulation of interleukin-6 production;GO:0007252//I-kappaB phosphorylation;GO:0043330//response to exogenous dsRNA;GO:0042742//defense response to bacterium;GO:0050729//positive regulation of inflammatory response;GO:0006972//hyperosmotic response;GO:0043331//response to dsRNA;GO:0032735//positive regulation of interleukin-12 production;GO:0045078//positive regulation of interferon-gamma biosynthetic process;GO:0034346//positive regulation of type III interferon production;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0034138//toll-like receptor 3 signaling pathway;GO:0032728//positive regulation of interferon-beta production;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0009597//detection of virus;GO:0051607//defense response to virus;GO:0071360//cellular response to exogenous dsRNA;GO:0097527//necroptotic signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:0042346//positive regulation of NF-kappaB import into nucleus;GO:0006954//inflammatory response;GO:0034128//negative regulation of MyD88-independent toll-like receptor signaling pathway;GO:0045359//positive regulation of interferon-beta biosynthetic process;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0045080//positive regulation of chemokine biosynthetic process;GO:0070266//necroptotic process;GO:0002730//regulation of dendritic cell cytokine production;GO:0002282//microglial cell activation involved in immune response;GO:0032722//positive regulation of chemokine production;GO:0045356//positive regulation of interferon-alpha biosynthetic process","K05401//toll-like receptor 3","NP_003256.1//toll-like receptor 3 precursor [Homo sapiens]","2//1"]
[80380,2418,0.03,0.17,2.50250034052918,0.226938461183459,"*",0.1243658,"PDCD1LG2","NA","NA","NA","K06708//programmed cell death 1 ligand 2","XP_010363386.1//PREDICTED: programmed cell death 1 ligand 2 isoform X1 [Rhinopithecus roxellana]","3//A2MP1"]
[3601,1689,1.08,5.82,2.42998784074482,{"v":9.81377108722109e-17,"d":"9.81E-17"},"Up",{"v":6.05758e-18,"d":"6.06E-18"},"IL15RA","GO:0031965//nuclear membrane;GO:0005615//extracellular space;GO:0031410//cytoplasmic vesicle;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0000139//Golgi membrane;GO:0030659//cytoplasmic vesicle membrane","GO:0004896//cytokine receptor activity;GO:0004871//signal transducer activity","GO:0010977//negative regulation of neuron projection development;GO:0007259//JAK-STAT cascade;GO:0007165//signal transduction;GO:0008283//cell proliferation;GO:0031667//response to nutrient levels;GO:0032825//positive regulation of natural killer cell differentiation","K05074//interleukin 15 receptor alpha","XP_001146125.2//PREDICTED: interleukin-15 receptor subunit alpha isoform X1 [Pan troglodytes];XP_011517771.1//PREDICTED: interleukin-15 receptor subunit alpha isoform X9 [Homo sapiens];XP_003312489.1//PREDICTED: interleukin-15 receptor subunit alpha isoform X3 [Pan troglodytes];NP_001338024.1//interleukin-15 receptor subunit alpha isoform 5 [Homo sapiens];NP_001243694.1//interleukin-15 receptor subunit alpha isoform 4 [Homo sapiens];XP_016871684.1//PREDICTED: interleukin-15 receptor subunit alpha isoform X11 [Homo sapiens];XP_011517768.1//PREDICTED: interleukin-15 receptor subunit alpha isoform X6 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[64386,3565,0.71,3.72,2.38941169160335,{"v":3.82628464842105E-22,"d":"3.83E-22"},"Up",{"v":1.592888e-23,"d":"1.59E-23"},"MMP25","GO:0031012//extracellular matrix;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding","GO:0060022//hard palate development;GO:0006954//inflammatory response","K08003//matrix metalloproteinase-25 (membrane-inserted) [EC:3.4.24.-]","XP_017719384.1//PREDICTED: matrix metalloproteinase-25 [Rhinopithecus bieti]",4]
[80271,3398,4.91,25.56,2.3800929066323,{"v":2.10853804875e-142,"d":"2.11E-142"},"Up",{"v":8.44788e-145,"d":"8.45E-145"},"ITPKC","GO:0005829//cytosol;GO:0016607//nuclear speck","GO:0005524//ATP binding;GO:0008440//inositol-1,4,5-trisphosphate 3-kinase activity;GO:0005516//calmodulin binding","GO:0043647//inositol phosphate metabolic process","K00911//1D-myo-inositol-triphosphate 3-kinase [EC:2.7.1.127]","NP_079470.1//inositol-trisphosphate 3-kinase C [Homo sapiens]","2//1"]
[5880,1538,0.05,0.26,2.37851162325373,0.226990320978062,"*",0.1243658,"RAC2","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005925//focal adhesion;GO:0005635//nuclear envelope;GO:0005622//intracellular;GO:0030670//phagocytic vesicle membrane;GO:0005737//cytoplasm;GO:0030027//lamellipodium;GO:0005884//actin filament;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0019887//protein kinase regulator activity;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:1902622//regulation of neutrophil migration;GO:0071593//lymphocyte aggregation;GO:1903955//positive regulation of protein targeting to mitochondrion;GO:0030168//platelet activation;GO:0060263//regulation of respiratory burst;GO:0007015//actin filament organization;GO:0042129//regulation of T cell proliferation;GO:0007264//small GTPase mediated signal transduction;GO:0010310//regulation of hydrogen peroxide metabolic process;GO:0043304//regulation of mast cell degranulation;GO:0060753//regulation of mast cell chemotaxis;GO:0006935//chemotaxis;GO:0030031//cell projection assembly;GO:0045453//bone resorption;GO:0007186//G-protein coupled receptor signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0007165//signal transduction;GO:0090023//positive regulation of neutrophil chemotaxis;GO:0010592//positive regulation of lamellipodium assembly;GO:0010810//regulation of cell-substrate adhesion;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0008284//positive regulation of cell proliferation","K07860//Ras-related C3 botulinum toxin substrate 2","AAD27003.1//HSPC022 [Homo sapiens]",4]
[3872,1574,0.05,0.26,2.37851162325373,0.226912540171331,"*",0.1243658,"KRT17","GO:0070062//extracellular exosome;GO:0045111//intermediate filament cytoskeleton;GO:0005829//cytosol;GO:0071944//cell periphery;GO:0005882//intermediate filament;GO:0005737//cytoplasm","GO:0042289//MHC class II protein binding;GO:0005198//structural molecule activity;GO:0005200//structural constituent of cytoskeleton;GO:0032395//MHC class II receptor activity","GO:0007165//signal transduction;GO:0045109//intermediate filament organization;GO:0045727//positive regulation of translation;GO:0030307//positive regulation of cell growth;GO:0031424//keratinization;GO:0070268//cornification;GO:0008544//epidermis development;GO:0031069//hair follicle morphogenesis;GO:0051798//positive regulation of hair follicle development","K07604//type I keratin, acidic","XP_008010900.1//PREDICTED: keratin, type I cytoskeletal 17 [Chlorocebus sabaeus]","2//1"]
[3936,3808,0.06,0.31,2.36923380966572,0.012319214230226,"*",0.0043681,"LCP1","NA","NA","NA","K17276//plastin-2","XP_010356391.1//PREDICTED: plastin-2 [Rhinopithecus roxellana]",4]
[112476,2915,1.08,5.57,2.36664601517656,{"v":2.59790361967213E-30,"d":"2.60E-30"},"Up",{"v":6.94444e-32,"d":"6.94E-32"},"PRRT2","GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0045202//synapse;GO:0005886//plasma membrane;GO:0043005//neuron projection","GO:0017124//SH3 domain binding","GO:0050884//neuromuscular process controlling posture;GO:0009607//response to biotic stimulus","K00901//diacylglycerol kinase (ATP) [EC:2.7.1.107]","NP_001243371.1//proline-rich transmembrane protein 2 isoform 2 [Homo sapiens];XP_012360791.1//PREDICTED: proline-rich transmembrane protein 2 isoform X1 [Nomascus leucogenys];NP_660282.2//proline-rich transmembrane protein 2 isoform 1 [Homo sapiens]","1//3;2//1"]
[83666,4724,2.89,14.84,2.36034969412012,{"v":5.8524172e-99,"d":"5.85E-99"},"Up",{"v":3.59044e-101,"d":"3.59E-101"},"PARP9","GO:0016020//membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043234//protein complex;GO:0005739//mitochondrion;GO:0090734//site of DNA damage","GO:0042393//histone binding;GO:0097677//STAT family protein binding;GO:0003950//NAD+ ADP-ribosyltransferase activity;GO:0072570//ADP-D-ribose binding;GO:0004857//enzyme inhibitor activity;GO:0044389//ubiquitin-like protein ligase binding;GO:0001191//transcriptional repressor activity, RNA polymerase II transcription factor binding;GO:0019899//enzyme binding","GO:1900182//positive regulation of protein localization to nucleus;GO:0034356//NAD biosynthesis via nicotinamide riboside salvage pathway;GO:0016477//cell migration;GO:0060335//positive regulation of interferon-gamma-mediated signaling pathway;GO:0035563//positive regulation of chromatin binding;GO:0010629//negative regulation of gene expression;GO:0010608//posttranscriptional regulation of gene expression;GO:2001034//positive regulation of double-strand break repair via nonhomologous end joining;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006302//double-strand break repair;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0060330//regulation of response to interferon-gamma;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0043086//negative regulation of catalytic activity;GO:0002230//positive regulation of defense response to virus by host;GO:0006471//protein ADP-ribosylation","K15260//poly [ADP-ribose] polymerase 9 [EC:2.4.2.30]","NP_113646.2//poly [ADP-ribose] polymerase 9 isoform a [Homo sapiens];NP_001139575.1//poly [ADP-ribose] polymerase 9 isoform b [Homo sapiens];NP_001139578.1//poly [ADP-ribose] polymerase 9 isoform c [Homo sapiens]","1//3;2//1"]
[467,2134,1.27,6.49,2.35338998122697,{"v":9.09561891970803e-22,"d":"9.10E-22"},"Up",{"v":3.9004e-23,"d":"3.90E-23"},"ATF3","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:1990622//CHOP-ATF3 complex","GO:0003677//DNA binding;GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003714//transcription corepressor activity;GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0042803//protein homodimerization activity;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0034198//cellular response to amino acid starvation;GO:1903984//positive regulation of TRAIL-activated apoptotic signaling pathway;GO:0006094//gluconeogenesis;GO:1990440//positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0035914//skeletal muscle cell differentiation;GO:0061394//regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0036499//PERK-mediated unfolded protein response;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0008284//positive regulation of cell proliferation","K09032//activating transcription factor 3","OBS69098.1//hypothetical protein A6R68_02380 [Neotoma lepida];XP_007986692.1//PREDICTED: cyclic AMP-dependent transcription factor ATF-3 [Chlorocebus sabaeus];NP_001035709.1//cyclic AMP-dependent transcription factor ATF-3 isoform 2 [Homo sapiens];NP_001193415.1//cyclic AMP-dependent transcription factor ATF-3 isoform 5 [Homo sapiens]","3//A2MP1;2//1"]
[5745,2007,0.04,0.2,2.32192809488736,0.2270681551263,"*",0.1243658,"PTH1R","GO:0070062//extracellular exosome;GO:0016323//basolateral plasma membrane;GO:0005634//nucleus;GO:0016324//apical plasma membrane;GO:0031526//brush border membrane;GO:0005622//intracellular;GO:0005737//cytoplasm;GO:0043235//receptor complex;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004991//parathyroid hormone receptor activity;GO:0017046//peptide hormone binding;GO:0043621//protein self-association","GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0007166//cell surface receptor signaling pathway;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0006874//cellular calcium ion homeostasis;GO:0008285//negative regulation of cell proliferation;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0045453//bone resorption;GO:0007186//G-protein coupled receptor signaling pathway;GO:0030282//bone mineralization;GO:0007568//aging;GO:0060732//positive regulation of inositol phosphate biosynthetic process;GO:0048469//cell maturation;GO:0002062//chondrocyte differentiation;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0001501//skeletal system development;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0002076//osteoblast development;GO:0008284//positive regulation of cell proliferation","K04585//parathyroid hormone receptor 1","NP_000307.1//parathyroid hormone/parathyroid hormone-related peptide receptor precursor [Homo sapiens]","1//3;2//1"]
[8528,1733,0.01,0.05,2.32192809488736,0.655661882546471,"*",0.499032,"DDO","GO:0005782//peroxisomal matrix;GO:0005777//peroxisome","GO:0008445//D-aspartate oxidase activity;GO:0005102//receptor binding;GO:0048037//cofactor binding;GO:0071949//FAD binding","GO:0019478//D-amino acid catabolic process;GO:0007320//insemination;GO:0042445//hormone metabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0006531//aspartate metabolic process;GO:0007625//grooming behavior;GO:0006533//aspartate catabolic process","K00272//D-aspartate oxidase [EC:1.4.3.1]","NP_003640.2//D-aspartate oxidase isoform a [Homo sapiens];NP_004023.2//D-aspartate oxidase isoform b [Homo sapiens]","2//1"]
[92369,2945,0.01,0.05,2.32192809488736,0.395579463143255,"*",0.249274,"SPSB4","GO:0005829//cytosol;GO:0005622//intracellular","NA","GO:0043687//post-translational protein modification;GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction","K10343//SPRY domain-containing SOCS box protein 1/4","NP_543138.1//SPRY domain-containing SOCS box protein 4 [Homo sapiens]","2//1"]
[3167,1628,0.01,0.05,2.32192809488736,0.653726190585534,"*",0.499032,"HMX2","GO:0005634//nucleus","GO:0043565//sequence-specific DNA binding","GO:0048026//positive regulation of mRNA splicing, via spliceosome;GO:0042472//inner ear morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0007420//brain development;GO:0008284//positive regulation of cell proliferation","K09349//homeobox protein Nkx-5","XP_007962514.1//PREDICTED: homeobox protein HMX2 [Chlorocebus sabaeus]","1//3"]
[1361,1655,0.01,0.05,2.32192809488736,0.653244052118332,"*",0.499032,"CPB2","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005623//cell;GO:0005576//extracellular region","GO:0008270//zinc ion binding;GO:0004181//metallocarboxypeptidase activity","GO:0042730//fibrinolysis;GO:0042493//response to drug;GO:0030449//regulation of complement activation;GO:0097421//liver regeneration;GO:0007596//blood coagulation;GO:2000346//negative regulation of hepatocyte proliferation;GO:0010757//negative regulation of plasminogen activation;GO:0003331//positive regulation of extracellular matrix constituent secretion;GO:0009408//response to heat;GO:0051918//negative regulation of fibrinolysis;GO:0071333//cellular response to glucose stimulus;GO:0006508//proteolysis","K01300//carboxypeptidase B2 [EC:3.4.17.20]","NP_001265470.1//carboxypeptidase B2 isoform 2 preproprotein [Homo sapiens];NP_001863.3//carboxypeptidase B2 isoform 1 preproprotein [Homo sapiens]","4;1//3"]
[55350,1723,0.01,0.05,2.32192809488736,0.653137006800492,"*",0.499032,"VNN3","NA","NA","NA","K08069//pantetheine hydrolase [EC:3.5.1.92]","CAB76824.1//VNN3 protein [Homo sapiens]","1//3"]
[139728,1522,0.01,0.05,2.32192809488736,0.652602306017192,"*",0.499032,"PNCK","GO:0005634//nucleus;GO:0005622//intracellular;GO:0005737//cytoplasm","GO:0005524//ATP binding;GO:0004683//calmodulin-dependent protein kinase activity;GO:0005516//calmodulin binding","GO:0018107//peptidyl-threonine phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0035556//intracellular signal transduction","K08795//pregnancy upregulated non-ubiquitously expressed CaM kinase [EC:2.7.11.17]","NP_001129212.1//calcium/calmodulin-dependent protein kinase type 1B isoform b [Homo sapiens];NP_001034671.3//calcium/calmodulin-dependent protein kinase type 1B isoform a [Homo sapiens]","1//3;3//A2MP1"]
[3854,2331,0.01,0.05,2.32192809488736,0.652548884086444,"*",0.499032,"KRT6B","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0045095//keratin filament","GO:0005198//structural molecule activity;GO:0005200//structural constituent of cytoskeleton","GO:0031424//keratinization;GO:0007398//ectoderm development;GO:0070268//cornification","K07605//type II keratin, basic","NP_005546.2//keratin, type II cytoskeletal 6B [Homo sapiens]","3//A2MP1"]
[921,3180,0.01,0.05,2.32192809488736,0.39479505016855,"*",0.249274,"CD5","GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005044//scavenger receptor activity;GO:0004872//receptor activity;GO:0004888//transmembrane signaling receptor activity","GO:0008283//cell proliferation;GO:0097190//apoptotic signaling pathway;GO:0008037//cell recognition;GO:0031295//T cell costimulation","K06455//T-cell surface glycoprotein CD5","NP_055022.2//T-cell surface glycoprotein CD5 isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[221188,3310,0.01,0.05,2.32192809488736,0.394755911172797,"*",0.249274,"ADGRG5","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004930//G-protein coupled receptor activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0007166//cell surface receptor signaling pathway","K08459//G protein-coupled receptor 114","NP_001305410.1//adhesion G-protein coupled receptor G5 isoform 2 precursor [Homo sapiens];NP_722579.1//adhesion G-protein coupled receptor G5 isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1;2//1"]
[2128,3049,0.01,0.05,2.32192809488736,0.394677656457528,"*",0.249274,"EVX1","GO:0005654//nucleoplasm","GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0006355//regulation of transcription, DNA-templated;GO:0021913//regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0009792//embryo development ending in birth or egg hatching","K09320//homeobox even-skipped homolog protein","NP_001980.1//homeobox even-skipped homolog protein 1 isoform 1 [Homo sapiens]","4;1//3"]
[9104,1637,0.01,0.05,2.32192809488736,0.651801894358136,"*",0.499032,"RGN","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0004341//gluconolactonase activity;GO:0005509//calcium ion binding;GO:0008270//zinc ion binding;GO:0030234//enzyme regulator activity","GO:0010867//positive regulation of triglyceride biosynthetic process;GO:0097421//liver regeneration;GO:0001822//kidney development;GO:0032515//negative regulation of phosphoprotein phosphatase activity;GO:1901671//positive regulation of superoxide dismutase activity;GO:0043547//positive regulation of GTPase activity;GO:0007283//spermatogenesis;GO:1903634//negative regulation of leucine-tRNA ligase activity;GO:1903611//negative regulation of calcium-dependent ATPase activity;GO:0019853//L-ascorbic acid biosynthetic process;GO:1903629//positive regulation of dUTP diphosphatase activity;GO:1901318//negative regulation of flagellated sperm motility;GO:0006874//cellular calcium ion homeostasis;GO:0010922//positive regulation of phosphatase activity;GO:0010907//positive regulation of glucose metabolic process;GO:0043066//negative regulation of apoptotic process;GO:1903011//negative regulation of bone development;GO:0045019//negative regulation of nitric oxide biosynthetic process;GO:1902679//negative regulation of RNA biosynthetic process;GO:0007568//aging;GO:2000279//negative regulation of DNA biosynthetic process;GO:0006469//negative regulation of protein kinase activity;GO:0045723//positive regulation of fatty acid biosynthetic process;GO:1901896//positive regulation of calcium-transporting ATPase activity;GO:0032781//positive regulation of ATPase activity;GO:0050848//regulation of calcium-mediated signaling;GO:1903625//negative regulation of DNA catabolic process;GO:0050680//negative regulation of epithelial cell proliferation;GO:0034260//negative regulation of GTPase activity;GO:0051344//negative regulation of cyclic-nucleotide phosphodiesterase activity;GO:1903052//positive regulation of proteolysis involved in cellular protein catabolic process","K01053//gluconolactonase [EC:3.1.1.17]","NP_001269778.1//regucalcin isoform 3 [Homo sapiens];NP_004674.1//regucalcin isoform 1 [Homo sapiens]","1//3;3//A2MP1;5"]
[56159,3151,0.04,0.2,2.32192809488736,0.085163198735569,"*",0.038791,"TEX11","GO:0000801//central element","NA","GO:0006311//meiotic gene conversion;GO:0000712//resolution of meiotic recombination intermediates;GO:0009566//fertilization;GO:0043066//negative regulation of apoptotic process;GO:0008584//male gonad development;GO:0007130//synaptonemal complex assembly;GO:0007131//reciprocal meiotic recombination;GO:0051026//chiasma assembly;GO:0007060//male meiosis chromosome segregation","K22069//LYR motif-containing protein 4;K12581//CCR4-NOT transcription complex subunit 7/8;K16506//protocadherin Fat 1/2/3;K18674//N-acetylgalactosamine kinase [EC:2.7.1.157];K07994//matrix metalloproteinase-13 (collagenase 3) [EC:3.4.24.-]","NP_001003811.1//testis-expressed protein 11 isoform 1 [Homo sapiens];NP_112566.2//testis-expressed protein 11 isoform 2 [Homo sapiens]","1//3;2//1"]
[7712,1695,0.01,0.05,2.32192809488736,0.65137581042654,"*",0.499032,"ZNF157","GO:0005622//intracellular","GO:0046872//metal ion binding;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","XP_012786440.1//PREDICTED: zinc finger protein 260-like [Ochotona princeps]","3//A2MP1"]
[3355,3242,0.01,0.05,2.32192809488736,0.394325893840364,"*",0.249274,"HTR1F","GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane","GO:0051378//serotonin binding;GO:0004993//G-protein coupled serotonin receptor activity;GO:0030594//neurotransmitter receptor activity","GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0007268//chemical synaptic transmission;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger","K04153//5-hydroxytryptamine receptor 1","NP_000857.1//5-hydroxytryptamine receptor 1F [Homo sapiens]","1//3;4"]
[7568,3073,0.01,0.05,2.32192809488736,0.394286847806714,"*",0.249274,"ZNF20","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_021532378.1//zinc finger protein 433 isoform X5 [Aotus nancymaae]","1//3;3//A2MP1"]
[79652,1647,0.01,0.05,2.32192809488736,0.650578402676895,"*",0.499032,"TMEM204","GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005912//adherens junction","NA","GO:0001945//lymph vessel development;GO:0051145//smooth muscle cell differentiation;GO:0030947//regulation of vascular endothelial growth factor receptor signaling pathway","NA","NP_078876.2//transmembrane protein 204 precursor [Homo sapiens]","1//3;5"]
[9421,1749,0.01,0.05,2.32192809488736,0.649782944897294,"*",0.499032,"HAND1","GO:0090575//RNA polymerase II transcription factor complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003714//transcription corepressor activity;GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0043425//bHLH transcription factor binding;GO:0003713//transcription coactivator activity;GO:0008134//transcription factor binding;GO:0019899//enzyme binding","GO:0003219//cardiac right ventricle formation;GO:0001829//trophectodermal cell differentiation;GO:0043433//negative regulation of DNA binding transcription factor activity;GO:0060485//mesenchyme development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0001707//mesoderm formation;GO:0001824//blastocyst development;GO:0060536//cartilage morphogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0060411//cardiac septum morphogenesis;GO:0001525//angiogenesis;GO:0007507//heart development;GO:1903026//negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003218//cardiac left ventricle formation;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0035050//embryonic heart tube development;GO:0060707//trophoblast giant cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0042475//odontogenesis of dentin-containing tooth;GO:0001947//heart looping;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0003144//embryonic heart tube formation","K09071//heart-and neural crest derivatives-expressed protein 1","NP_004812.1//heart- and neural crest derivatives-expressed protein 1 [Homo sapiens]","2//1"]
[56123,3503,0.01,0.05,2.32192809488736,0.394052733894112,"*",0.249274,"PCDHB13","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane","GO:0005509//calcium ion binding","GO:0007416//synapse assembly;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007268//chemical synaptic transmission;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules","K16494//protocadherin beta","NP_061756.1//protocadherin beta-13 precursor [Homo sapiens]","3//A2MP1"]
[100506736,1767,0.01,0.05,2.32192809488736,0.649412396578411,"*",0.499032,"SLFN12L","GO:0016021//integral component of membrane","GO:0005524//ATP binding","NA","NA","NP_001182719.1//schlafen family member 12-like [Homo sapiens]","1//3"]
[136259,1480,0.01,0.05,2.32192809488736,0.64925371949829,"*",0.499032,"KLF14","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003676//nucleic acid binding","GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:1902070//positive regulation of sphingolipid mediated signaling pathway","K09208//krueppel-like factor 9/13/14/16","NP_619638.2//Krueppel-like factor 14 [Homo sapiens]","3//A2MP1"]
[340654,1484,0.01,0.05,2.32192809488736,0.649042270639961,"*",0.499032,"LIPM","NA","GO:0016788//hydrolase activity, acting on ester bonds","GO:0016042//lipid catabolic process","K19406//lipase-like abhydrolase domain-containing protein 3 [EC:3.1.1.-]","XP_004049794.1//PREDICTED: lipase member M isoform X1 [Gorilla gorilla gorilla]","1//3"]
[3791,6055,0.01,0.05,2.32192809488736,0.226618225863051,"*",0.1245166,"KDR","GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0030054//cell junction;GO:0005768//endosome;GO:0097443//sorting endosome;GO:0005887//integral component of plasma membrane;GO:0045121//membrane raft;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005769//early endosome","GO:0038085//vascular endothelial growth factor binding;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0019838//growth factor binding;GO:0004716//signal transducer, downstream of receptor, with protein tyrosine kinase activity;GO:0005021//vascular endothelial growth factor-activated receptor activity;GO:0051879//Hsp90 protein binding;GO:0004713//protein tyrosine kinase activity;GO:0005178//integrin binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity","GO:0030335//positive regulation of cell migration;GO:0043491//protein kinase B signaling;GO:0010595//positive regulation of endothelial cell migration;GO:0070371//ERK1 and ERK2 cascade;GO:0051901//positive regulation of mitochondrial depolarization;GO:0045766//positive regulation of angiogenesis;GO:0001570//vasculogenesis;GO:0001525//angiogenesis;GO:0051894//positive regulation of focal adhesion assembly;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0043066//negative regulation of apoptotic process;GO:0016032//viral process;GO:0008360//regulation of cell shape;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:0046777//protein autophosphorylation;GO:0030198//extracellular matrix organization;GO:0038083//peptidyl-tyrosine autophosphorylation;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0035584//calcium-mediated signaling using intracellular calcium source;GO:0038033//positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0002042//cell migration involved in sprouting angiogenesis;GO:0050927//positive regulation of positive chemotaxis;GO:0035162//embryonic hemopoiesis;GO:0051770//positive regulation of nitric-oxide synthase biosynthetic process;GO:0001934//positive regulation of protein phosphorylation;GO:0001938//positive regulation of endothelial cell proliferation;GO:0003158//endothelium development;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0090141//positive regulation of mitochondrial fission;GO:2001214//positive regulation of vasculogenesis;GO:0016239//positive regulation of macroautophagy;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0043410//positive regulation of MAPK cascade;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0008284//positive regulation of cell proliferation","K05098//kinase insert domain protein receptor [EC:2.7.10.1]","BAD93138.1//kinase insert domain receptor (a type III receptor tyrosine kinase) variant, partial [Homo sapiens]","2//1"]
[348303,1629,0.01,0.05,2.32192809488736,0.648567013912619,"*",0.499032,"SELENOV","NA","NA","NA","K11661//helicase SRCAP [EC:3.6.4.-];K06051//delta","XP_016802414.1//PREDICTED: selenoprotein V-like isoform X1 [Pan troglodytes]","1//3"]
[121214,1765,0.01,0.05,2.32192809488736,0.648303283018868,"*",0.499032,"SDR9C7","GO:0005730//nucleolus;GO:0005829//cytosol","GO:0004745//retinol dehydrogenase activity","GO:0055114//oxidation-reduction process","K11154//retinol dehydrogenase 16 [EC:1.1.1.-];K13369//17beta-estradiol 17-dehydrogenase / all-trans-retinol dehydrogenase (NAD+) / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:1.1.1.62 1.1.1.105 1.1.1.239]","NP_683695.1//short-chain dehydrogenase/reductase family 9C member 7 [Homo sapiens]","2//1"]
[3351,3175,0.01,0.05,2.32192809488736,0.393585339132154,"*",0.249274,"HTR1B","GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0051378//serotonin binding;GO:0004993//G-protein coupled serotonin receptor activity;GO:0008144//drug binding;GO:0030594//neurotransmitter receptor activity","GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0007198//adenylate cyclase-inhibiting serotonin receptor signaling pathway;GO:0050795//regulation of behavior;GO:0035690//cellular response to drug;GO:0042310//vasoconstriction;GO:0014059//regulation of dopamine secretion;GO:0045471//response to ethanol;GO:1904707//positive regulation of vascular smooth muscle cell proliferation;GO:0014063//negative regulation of serotonin secretion;GO:0032229//negative regulation of synaptic transmission, GABAergic;GO:0071502//cellular response to temperature stimulus;GO:0042756//drinking behavior;GO:0051967//negative regulation of synaptic transmission, glutamatergic;GO:0030818//negative regulation of cAMP biosynthetic process;GO:0051385//response to mineralocorticoid;GO:0042493//response to drug;GO:0007631//feeding behavior;GO:0007268//chemical synaptic transmission;GO:0002031//G-protein coupled receptor internalization;GO:0046849//bone remodeling;GO:0042220//response to cocaine;GO:0071312//cellular response to alkaloid;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger","K04153//5-hydroxytryptamine receptor 1","NP_000854.1//5-hydroxytryptamine receptor 1B [Homo sapiens]","2//1"]
[100133251,1587,0.01,0.05,2.32192809488736,0.999970998684128,"*",0.999032,"PRR23D2","NA","NA","NA","NA","NP_001269407.1//proline-rich protein 23D2 [Homo sapiens]","1//3"]
[55843,1774,0.01,0.05,2.32192809488736,0.647145410618607,"*",0.499032,"ARHGAP15","GO:0016020//membrane;GO:0005829//cytosol","GO:0005096//GTPase activator activity","GO:0007165//signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0008360//regulation of cell shape","K20637//Rho GTPase-activating protein 15","NP_060930.3//rho GTPase-activating protein 15 [Homo sapiens]","3//A2MP1"]
[4208,6446,0.01,0.05,2.32192809488736,0.355993867621483,"*",0.217844,"MEF2C","GO:0043231//intracellular membrane-bounded organelle;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0098794//postsynapse;GO:0043234//protein complex;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0001046//core promoter sequence-specific DNA binding;GO:0046982//protein heterodimerization activity;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003680//AT DNA binding;GO:0000983//transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding;GO:0046983//protein dimerization activity;GO:0003682//chromatin binding;GO:0035198//miRNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0033613//activating transcription factor binding","GO:0014902//myotube differentiation;GO:0071374//cellular response to parathyroid hormone stimulus;GO:0001568//blood vessel development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0050853//B cell receptor signaling pathway;GO:0000165//MAPK cascade;GO:0030182//neuron differentiation;GO:0007507//heart development;GO:0006351//transcription, DNA-templated;GO:0006915//apoptotic process;GO:0042100//B cell proliferation;GO:0030279//negative regulation of ossification;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:2001016//positive regulation of skeletal muscle cell differentiation;GO:2000727//positive regulation of cardiac muscle cell differentiation;GO:0045663//positive regulation of myoblast differentiation;GO:0001782//B cell homeostasis;GO:0009615//response to virus","K04454//MADS-box transcription enhancer factor 2C","NP_001180276.1//myocyte-specific enhancer factor 2C isoform 3 [Homo sapiens];NP_001180278.1//myocyte-specific enhancer factor 2C isoform 5 [Homo sapiens];NP_001180277.1//myocyte-specific enhancer factor 2C isoform 4 [Homo sapiens];EAW95965.1//MADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C), isoform CRA_d [Homo sapiens];EAW95967.1//MADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C), isoform CRA_f [Homo sapiens]","4;1//3;2//1"]
[286187,799,0.01,0.05,2.32192809488736,0.646253519902716,"*",0.499032,"PPP1R42","GO:0005815//microtubule organizing center;GO:0015630//microtubule cytoskeleton;GO:0002177//manchette;GO:0005813//centrosome;GO:0005737//cytoplasm","GO:0015631//tubulin binding;GO:0070840//dynein complex binding;GO:0003779//actin binding;GO:0008092//cytoskeletal protein binding","GO:0010921//regulation of phosphatase activity","K17579//protein phosphatase 1 regulatory subunit 42","NP_001013648.1//protein phosphatase 1 regulatory subunit 42 isoform 1 [Homo sapiens];NP_001335492.1//protein phosphatase 1 regulatory subunit 42 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[1180,3093,0.01,0.05,2.32192809488736,0.39288632224963,"*",0.249274,"CLCN1","GO:0005887//integral component of plasma membrane;GO:0042383//sarcolemma;GO:0034707//chloride channel complex;GO:0005886//plasma membrane","GO:0005247//voltage-gated chloride channel activity;GO:0042803//protein homodimerization activity","GO:0006936//muscle contraction;GO:0034220//ion transmembrane transport;GO:0019227//neuronal action potential propagation;GO:1902476//chloride transmembrane transport","K05010//chloride channel 1, skeletal muscle","XP_527935.3//PREDICTED: chloride channel protein 1 isoform X1 [Pan troglodytes]","2//1"]
[57047,1598,0.01,0.05,2.32192809488736,0.644946372815534,"*",0.499032,"PLSCR2","GO:0005634//nucleus;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0017128//phospholipid scramblase activity;GO:0005509//calcium ion binding","GO:0017121//phospholipid scrambling","NA","XP_011511315.2//PREDICTED: phospholipid scramblase 2 isoform X1 [Homo sapiens];EHH16696.1//hypothetical protein EGK_12025 [Macaca mulatta];NP_001186907.1//phospholipid scramblase 2 isoform 1 [Homo sapiens]","1//3;2//1"]
[254187,1726,0.01,0.05,2.32192809488736,0.644581318670656,"*",0.499032,"TSGA10IP","NA","NA","NA","K16772//protein FAM161A","NP_689975.2//testis-specific protein 10-interacting protein [Homo sapiens]","2//1"]
[285641,2983,0.01,0.05,2.32192809488736,0.644320818622696,"*",0.499032,"SLC36A3","GO:0005774//vacuolar membrane;GO:0016021//integral component of membrane","GO:0015193//L-proline transmembrane transporter activity;GO:0015187//glycine transmembrane transporter activity;GO:0015180//L-alanine transmembrane transporter activity;GO:0005280//hydrogen:amino acid symporter activity;GO:0015078//hydrogen ion transmembrane transporter activity","GO:0015816//glycine transport","K14209//solute carrier family 36 (proton-coupled amino acid transporter)","XP_010371987.1//PREDICTED: proton-coupled amino acid transporter 3 isoform X2 [Rhinopithecus roxellana];NP_001138489.1//proton-coupled amino acid transporter 3 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[254158,1547,0.01,0.05,2.32192809488736,0.644268743877798,"*",0.499032,"CXorf58","NA","NA","NA","NA","NP_689974.2//putative uncharacterized protein CXorf58 isoform 1 [Homo sapiens];NP_001163045.1//putative uncharacterized protein CXorf58 isoform 2 [Homo sapiens]","1//3;2//1"]
[1010,3709,0.02,0.1,2.32192809488736,0.35588464471262,"*",0.217844,"CDH12","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005509//calcium ion binding","GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules","K06804//cadherin 12, type 2, N-cadherin 2","XP_005386198.1//PREDICTED: cadherin-12 [Chinchilla lanigera];XP_020932697.1//cadherin-12 isoform X2 [Sus scrofa]","4;1//3"]
[388960,2990,0.01,0.05,2.32192809488736,0.392383018919984,"*",0.249274,"C2orf78","NA","NA","NA","K10431//microtubule-associated protein 4;K22016//mucin-3/17","NP_001073943.1//uncharacterized protein C2orf78 [Homo sapiens]","1//3"]
[160419,1705,0.01,0.05,2.32192809488736,0.643436691258374,"*",0.499032,"C12orf50","NA","NA","NA","NA","XP_016874376.1//PREDICTED: uncharacterized protein C12orf50 isoform X2 [Homo sapiens]","1//3"]
[91646,1617,0.01,0.05,2.32192809488736,0.643384759322034,"*",0.499032,"TDRD12","NA","NA","NA","K18409//ATP-dependent RNA helicase TDRD12 [EC:3.6.4.13]","XP_007994405.1//PREDICTED: putative ATP-dependent RNA helicase TDRD12 isoform X1 [Chlorocebus sabaeus]","1//3"]
[84824,2227,0.01,0.05,2.32192809488736,0.643073343659245,"*",0.499032,"FCRLA","GO:0016021//integral component of membrane;GO:0005737//cytoplasm","NA","GO:0030154//cell differentiation","K17273//Fc receptor-like protein 6","NP_001171802.1//Fc receptor-like A isoform 6 precursor [Homo sapiens];NP_001171799.1//Fc receptor-like A isoform 4 precursor [Homo sapiens];NP_116127.3//Fc receptor-like A isoform 2 precursor [Homo sapiens];NP_001171796.1//Fc receptor-like A isoform 3 precursor [Homo sapiens];NP_001171800.1//Fc receptor-like A isoform 7 precursor [Homo sapiens];NP_001171801.1//Fc receptor-like A isoform 5 precursor [Homo sapiens];NP_001171795.1//Fc receptor-like A isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[3624,6105,0.01,0.05,2.32192809488736,0.355811866666667,"*",0.217844,"INHBA","GO:0005615//extracellular space;GO:0043512//inhibin A complex;GO:0043509//activin A complex;GO:0005576//extracellular region;GO:0048471//perinuclear region of cytoplasm","GO:0008083//growth factor activity;GO:0005125//cytokine activity;GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity;GO:0034711//inhibin binding;GO:0005160//transforming growth factor beta receptor binding;GO:0005179//hormone activity;GO:0017046//peptide hormone binding;GO:0070699//type II activin receptor binding","GO:0045786//negative regulation of cell cycle;GO:0097191//extrinsic apoptotic signaling pathway;GO:0032270//positive regulation of cellular protein metabolic process;GO:0007166//cell surface receptor signaling pathway;GO:0008584//male gonad development;GO:0051799//negative regulation of hair follicle development;GO:0048468//cell development;GO:0008285//negative regulation of cell proliferation;GO:0060279//positive regulation of ovulation;GO:0042493//response to drug;GO:0030154//cell differentiation;GO:0043408//regulation of MAPK cascade;GO:0010628//positive regulation of gene expression;GO:0001541//ovarian follicle development;GO:0042326//negative regulation of phosphorylation;GO:0032924//activin receptor signaling pathway;GO:0046882//negative regulation of follicle-stimulating hormone secretion;GO:0071397//cellular response to cholesterol;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:2001241//positive regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0045648//positive regulation of erythrocyte differentiation;GO:0000082//G1/S transition of mitotic cell cycle;GO:0045077//negative regulation of interferon-gamma biosynthetic process;GO:0021773//striatal medium spiny neuron differentiation;GO:0007399//nervous system development;GO:0002244//hematopoietic progenitor cell differentiation;GO:0035987//endodermal cell differentiation;GO:0042541//hemoglobin biosynthetic process;GO:0007050//cell cycle arrest;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046881//positive regulation of follicle-stimulating hormone secretion;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0045650//negative regulation of macrophage differentiation;GO:0048333//mesodermal cell differentiation;GO:0060021//palate development;GO:0071372//cellular response to follicle-stimulating hormone stimulus;GO:0042476//odontogenesis;GO:0030308//negative regulation of cell growth;GO:0042701//progesterone secretion;GO:0061029//eyelid development in camera-type eye;GO:0007267//cell-cell signaling;GO:0030218//erythrocyte differentiation;GO:0060395//SMAD protein signal transduction;GO:0045578//negative regulation of B cell differentiation;GO:0006952//defense response;GO:0097154//GABAergic neuron differentiation;GO:0042981//regulation of apoptotic process;GO:0001942//hair follicle development;GO:0046880//regulation of follicle-stimulating hormone secretion","K04667//inhibin, beta","XP_016867663.1//PREDICTED: inhibin beta A chain isoform X1 [Homo sapiens]","3//A2MP1"]
[155184,1539,0.01,0.05,2.32192809488736,0.642244373831776,"*",0.499032,"SLC2A7","NA","NA","NA","K12201//MFS transporter, SP family, solute carrier family 2 (facilitated glucose/fructose transporter), member 7","XP_017358768.1//PREDICTED: solute carrier family 2, facilitated glucose transporter member 7 [Cebus capucinus imitator]","2//1"]
[10590,1492,0.01,0.05,2.32192809488736,0.642089179863069,"*",0.499032,"SCGN","GO:0030658//transport vesicle membrane;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005576//extracellular region;GO:0045202//synapse;GO:0005737//cytoplasm;GO:0043005//neuron projection","GO:0005509//calcium ion binding","GO:0051480//regulation of cytosolic calcium ion concentration","K14757//calbindin D28","NP_008929.2//secretagogin [Homo sapiens]","3//A2MP1"]
[53836,1521,0.01,0.05,2.32192809488736,0.641520776436504,"*",0.499032,"GPR87","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane","GO:0045028//G-protein coupled purinergic nucleotide receptor activity","GO:0007194//negative regulation of adenylate cyclase activity","K08389//G protein-coupled receptor 87","NP_076404.3//G-protein coupled receptor 87 [Homo sapiens]","3//A2MP1"]
[1158,1666,0.01,0.05,2.32192809488736,0.641469153295244,"*",0.499032,"CKM","NA","GO:0005524//ATP binding;GO:0004111//creatine kinase activity","GO:0046314//phosphocreatine biosynthetic process","K00933//creatine kinase [EC:2.7.3.2]","XP_010612927.2//PREDICTED: creatine kinase M-type [Fukomys damarensis]",4]
[27285,1536,0.01,0.05,2.32192809488736,0.641004918623352,"*",0.499032,"TEKT2","GO:0036126//sperm flagellum;GO:0005634//nucleus;GO:0005815//microtubule organizing center;GO:0005874//microtubule;GO:0005737//cytoplasm","NA","GO:0060294//cilium movement involved in cell motility;GO:0030317//flagellated sperm motility;GO:0060271//cilium assembly;GO:0036159//inner dynein arm assembly","K18629//tektin-2","NP_055281.2//tektin-2 [Homo sapiens]","2//1"]
[4100,1755,0.01,0.05,2.32192809488736,0.640129861720067,"*",0.499032,"MAGEA1","GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0042826//histone deacetylase binding","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045746//negative regulation of Notch signaling pathway;GO:0006351//transcription, DNA-templated","K12464//melanoma-associated antigen D1","NP_004979.3//melanoma-associated antigen 1 [Homo sapiens]",4]
[3860,1718,0.01,0.05,2.32192809488736,0.639975687861272,"*",0.499032,"KRT13","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0045111//intermediate filament cytoskeleton;GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament","GO:0005198//structural molecule activity","GO:0071300//cellular response to retinoic acid;GO:0009314//response to radiation;GO:0007010//cytoskeleton organization;GO:0043587//tongue morphogenesis;GO:0031424//keratinization;GO:0070268//cornification","K07604//type I keratin, acidic","NP_705694.2//keratin, type I cytoskeletal 13 isoform a [Homo sapiens];NP_002265.2//keratin, type I cytoskeletal 13 isoform b [Homo sapiens]","3//A2MP1;2//1"]
[5673,1601,0.01,0.05,2.32192809488736,0.639667562831006,"*",0.499032,"PSG5","NA","NA","NA","K06500//pregnancy specific beta-1-glycoprotein","XP_009230959.1//PREDICTED: pregnancy-specific beta-1-glycoprotein 5 isoform X4 [Pongo abelii]","1//3;3//A2MP1"]
[11250,1725,0.01,0.05,2.32192809488736,0.639616237503009,"*",0.499032,"GPR45","NA","NA","NA","K08409//G protein-coupled receptor 45","XP_515672.3//PREDICTED: probable G-protein coupled receptor 45 [Pan troglodytes]","3//A2MP1"]
[160762,1745,0.01,0.05,2.32192809488736,0.639513611552347,"*",0.499032,"CCDC63","GO:0005930//axoneme","NA","GO:0003341//cilium movement;GO:0007286//spermatid development;GO:0036158//outer dynein arm assembly","K10352//myosin heavy chain;K20282//GRIP and coiled-coil domain-containing protein 2;K06102//cingulin;K18626//trichohyalin;K16469//rootletin","AAH64580.1//CCDC63 protein, partial [Homo sapiens];NP_689804.1//coiled-coil domain-containing protein 63 isoform 1 [Homo sapiens]","1//3;2//1"]
[22914,1606,0.01,0.05,2.32192809488736,0.639462310925718,"*",0.499032,"KLRK1","GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0030246//carbohydrate binding;GO:0004872//receptor activity;GO:0032394//MHC class Ib receptor activity;GO:0042288//MHC class I protein binding;GO:0042803//protein homodimerization activity","GO:0007165//signal transduction;GO:0042267//natural killer cell mediated cytotoxicity;GO:0030154//cell differentiation;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0071222//cellular response to lipopolysaccharide;GO:0031295//T cell costimulation;GO:0002250//adaptive immune response;GO:0030101//natural killer cell activation;GO:2000502//negative regulation of natural killer cell chemotaxis;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0050830//defense response to Gram-positive bacterium;GO:0034260//negative regulation of GTPase activity;GO:0050776//regulation of immune response;GO:0032729//positive regulation of interferon-gamma production","K06728//killer cell lectin-like receptor subfamily K member 1","NP_031386.2//NKG2-D type II integral membrane protein [Homo sapiens]","3//A2MP1"]
[5920,779,0.54,2.68,2.3112016882943,6.95121570873786E-4,"Up",0.0001882494,"RARRES3","GO:0005829//cytosol;GO:0016021//integral component of membrane","GO:0016746//transferase activity, transferring acyl groups;GO:0004623//phospholipase A2 activity","GO:0036152//phosphatidylethanolamine acyl-chain remodeling;GO:0016042//lipid catabolic process;GO:0006644//phospholipid metabolic process;GO:0008285//negative regulation of cell proliferation","K16817//HRAS-like suppressor 3 [EC:3.1.1.32 3.1.1.4]","NP_004576.2//retinoic acid receptor responder protein 3 [Homo sapiens]",4]
[3133,2679,23.73,116.58,2.29653630111255,0,"Up",0,"HLA-E","NA","NA","NA","K06751//major histocompatibility complex, class I","XP_010366495.1//PREDICTED: LOW QUALITY PROTEIN: patr class I histocompatibility antigen, alpha chain E [Rhinopithecus roxellana]",5]
[129607,3014,0.11,0.53,2.2684888359259,0.00291156719136808,"*",0.000895306,"CMPK2","GO:0005739//mitochondrion;GO:0005737//cytoplasm","GO:0004798//thymidylate kinase activity;GO:0009041//uridylate kinase activity;GO:0005524//ATP binding;GO:0033862//UMP kinase activity;GO:0004550//nucleoside diphosphate kinase activity;GO:0004127//cytidylate kinase activity","GO:0006165//nucleoside diphosphate phosphorylation;GO:0006233//dTDP biosynthetic process;GO:0006235//dTTP biosynthetic process;GO:0071222//cellular response to lipopolysaccharide;GO:0006227//dUDP biosynthetic process;GO:0009142//nucleoside triphosphate biosynthetic process","K13809//UMP-CMP kinase 2, mitochondrial [EC:2.7.4.14]","NP_997198.2//UMP-CMP kinase 2, mitochondrial isoform 1 precursor [Homo sapiens];NP_001243407.1//UMP-CMP kinase 2, mitochondrial isoform 3 precursor [Homo sapiens];NP_001243406.1//UMP-CMP kinase 2, mitochondrial isoform 2 precursor [Homo sapiens]","1//3;3//A2MP1"]
[400629,1951,0.25,1.19,2.25096157353322,0.000272403588058204,"Up",{"v":6.7973e-05,"d":"6.80E-05"},"TEX19","NA","NA","NA","NA","XP_012511813.1//PREDICTED: testis-expressed protein 19.2-like [Propithecus coquereli]","3//A2MP1"]
[100288797,3114,0.43,2.03,2.23907116248308,{"v":4.04117270588235e-07,"d":"4.04E-07"},"Up",{"v":6.32208e-08,"d":"6.32E-08"},"TMEM239","GO:0016021//integral component of membrane","NA","NA","K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K15696//RING finger protein 113B;K17985//activating molecule in BECN1-regulated autophagy protein 1;K01064//wingless-type MMTV integration site family, member 9","BAC85208.1//unnamed protein product [Homo sapiens];NP_001305136.1//transmembrane protein 239 isoform 1 [Homo sapiens]","1//3;2//1"]
[440093,1071,0.26,1.22,2.23029761942179,0.0123170396116505,"*",0.0043681,"H3F3C","GO:0005719//nuclear euchromatin;GO:0000786//nucleosome","GO:0046982//protein heterodimerization activity;GO:0031492//nucleosomal DNA binding","GO:0006334//nucleosome assembly;GO:0030307//positive regulation of cell growth","K11253//histone H3","XP_007451114.1//PREDICTED: histone H3.3-like [Lipotes vexillifer]","2//1"]
[3569,1197,0.68,3.14,2.20715790764129,{"v":3.97976719394773e-06,"d":"3.98E-06"},"Up",{"v":7.245e-07,"d":"7.25E-07"},"IL6","GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0009897//external side of plasma membrane;GO:0005896//interleukin-6 receptor complex;GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0005138//interleukin-6 receptor binding;GO:0008083//growth factor activity;GO:0005125//cytokine activity","GO:0045079//negative regulation of chemokine biosynthetic process;GO:0002675//positive regulation of acute inflammatory response;GO:0045630//positive regulation of T-helper 2 cell differentiation;GO:0042102//positive regulation of T cell proliferation;GO:0071222//cellular response to lipopolysaccharide;GO:0071356//cellular response to tumor necrosis factor;GO:0042593//glucose homeostasis;GO:0045779//negative regulation of bone resorption;GO:0043065//positive regulation of apoptotic process;GO:0001781//neutrophil apoptotic process;GO:0071347//cellular response to interleukin-1;GO:0070102//interleukin-6-mediated signaling pathway;GO:0010574//regulation of vascular endothelial growth factor production;GO:0070091//glucagon secretion;GO:0070301//cellular response to hydrogen peroxide;GO:0009611//response to wounding;GO:0035729//cellular response to hepatocyte growth factor stimulus;GO:0050871//positive regulation of B cell activation;GO:2000660//negative regulation of interleukin-1-mediated signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0031018//endocrine pancreas development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0002384//hepatic immune response;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0072540//T-helper 17 cell lineage commitment;GO:0060445//branching involved in salivary gland morphogenesis;GO:0032755//positive regulation of interleukin-6 production;GO:0045727//positive regulation of translation;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0051024//positive regulation of immunoglobulin secretion;GO:0031175//neuron projection development;GO:0051384//response to glucocorticoid;GO:0071864//positive regulation of cell proliferation in bone marrow;GO:0060664//epithelial cell proliferation involved in salivary gland morphogenesis;GO:0042832//defense response to protozoan;GO:0032966//negative regulation of collagen biosynthetic process;GO:2000553//positive regulation of T-helper 2 cell cytokine production;GO:0046888//negative regulation of hormone secretion;GO:0051607//defense response to virus;GO:0006953//acute-phase response;GO:0002526//acute inflammatory response;GO:0007568//aging;GO:0006954//inflammatory response;GO:0046716//muscle cell cellular homeostasis;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0043410//positive regulation of MAPK cascade;GO:0006955//immune response;GO:0046849//bone remodeling;GO:0032722//positive regulation of chemokine production;GO:0050679//positive regulation of epithelial cell proliferation","K05405//interleukin 6","XP_011729449.1//PREDICTED: interleukin-6 isoform X3 [Macaca nemestrina];XP_017830595.1//PREDICTED: interleukin-6 isoform X1 [Callithrix jacchus]","1//3;4"]
[11067,2060,0.12,0.55,2.1963972128035,0.019868529492318,"*",0.0074479,"DEPP1","GO:0005739//mitochondrion;GO:0005737//cytoplasm","NA","NA","NA","NP_008952.1//protein DEPP [Homo sapiens]","3//A2MP1"]
[1154,2163,1.62,7.42,2.19542537373618,{"v":8.1548991907131e-24,"d":"8.15E-24"},"Up",{"v":3.07838e-25,"d":"3.08E-25"},"CISH","GO:0005829//cytosol;GO:0005622//intracellular;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0004860//protein kinase inhibitor activity","GO:0001558//regulation of cell growth;GO:0043687//post-translational protein modification;GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0016567//protein ubiquitination;GO:0046426//negative regulation of JAK-STAT cascade;GO:0035556//intracellular signal transduction;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0006469//negative regulation of protein kinase activity;GO:0019221//cytokine-mediated signaling pathway","K04701//cytokine inducible SH2-containing protein","NP_037456.5//cytokine-inducible SH2-containing protein isoform 1 [Homo sapiens];NP_659508.1//cytokine-inducible SH2-containing protein isoform 2 [Homo sapiens]","2//1;5"]
[84159,7226,0.37,1.67,2.1742509268451,{"v":3.04226467425968e-18,"d":"3.04E-18"},"Up",{"v":1.67216E-19,"d":"1.67E-19"},"ARID5B","GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0003677//DNA binding;GO:0003713//transcription coactivator activity;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0032452//histone demethylase activity;GO:0001227//transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding","GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0001822//kidney development;GO:0006355//regulation of transcription, DNA-templated;GO:0008584//male gonad development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0009791//post-embryonic development;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0060021//palate development;GO:0048468//cell development;GO:0060613//fat pad development;GO:0048705//skeletal system morphogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0001889//liver development;GO:0006351//transcription, DNA-templated;GO:0060612//adipose tissue development;GO:0010761//fibroblast migration;GO:0035264//multicellular organism growth;GO:0008585//female gonad development;GO:0048644//muscle organ morphogenesis;GO:1990830//cellular response to leukemia inhibitory factor;GO:0045444//fat cell differentiation;GO:0030325//adrenal gland development;GO:0060325//face morphogenesis","K07874//Ras-related protein Rab-1A;K00844//hexokinase [EC:2.7.1.1];K19195//AT-rich interactive domain-containing protein 4B","NP_115575.1//AT-rich interactive domain-containing protein 5B isoform 1 [Homo sapiens];NP_001231567.1//AT-rich interactive domain-containing protein 5B isoform 2 [Homo sapiens]","1//3;2//1"]
[23584,1299,0.06,0.27,2.16992500144231,0.356394925850061,"*",0.217844,"VSIG2","GO:0016020//membrane;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane","NA","NA","K06791//immunoglobulin superfamily, member 11","XP_010382927.1//PREDICTED: V-set and immunoglobulin domain-containing protein 2 [Rhinopithecus roxellana]","4;1//3"]
[285195,3647,0.02,0.09,2.16992500144231,0.356321938971943,"*",0.217844,"SLC9A9","GO:0031902//late endosome membrane;GO:0016021//integral component of membrane;GO:0055037//recycling endosome;GO:0005886//plasma membrane","GO:0015386//potassium:proton antiporter activity;GO:0015385//sodium:proton antiporter activity","GO:0098719//sodium ion import across plasma membrane;GO:0006885//regulation of pH;GO:0051453//regulation of intracellular pH;GO:0071805//potassium ion transmembrane transport;GO:0006811//ion transport","K14725//solute carrier family 9 (sodium/hydrogen exchanger), member 9","NP_775924.1//sodium/hydrogen exchanger 9 [Homo sapiens]","3//A2MP1"]
[339768,3631,0.02,0.09,2.16992500144231,0.227016259764598,"*",0.1243658,"ESPNL","GO:0032426//stereocilium tip;GO:0005737//cytoplasm","GO:0051015//actin filament binding","GO:0007605//sensory perception of sound;GO:0051017//actin filament bundle assembly","K15503//serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B;K19721//collagen, type V/XI/XXIV/XXVII, alpha;K10466//kelch-like protein 30;K14211//elastin;K19720//collagen, type III, alpha","NP_919288.2//espin-like protein isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[645426,1325,0.48,2.16,2.16992500144231,{"v":4.01936662160601e-05,"d":"4.02E-05"},"Up",{"v":8.71106e-06,"d":"8.71E-06"},"TMEM191C","GO:0016021//integral component of membrane","NA","NA","K06236//collagen, type I, alpha","NP_001193981.1//transmembrane protein 191C [Homo sapiens]","1//3"]
[146183,2718,0.02,0.09,2.16992500144231,0.530230126986946,"*",0.37379,"OTOA","GO:0009986//cell surface;GO:0016324//apical plasma membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0031225//anchored component of membrane;GO:0005578//proteinaceous extracellular matrix","NA","GO:0007160//cell-matrix adhesion;GO:0006501//C-terminal protein lipidation;GO:0019226//transmission of nerve impulse;GO:0007605//sensory perception of sound","K20733//mesothelin","NP_733764.1//otoancorin isoform 2 [Homo sapiens];NP_001155155.1//otoancorin isoform 3 [Homo sapiens];NP_653273.3//otoancorin isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1;2//1"]
[3090,3071,0.13,0.58,2.15754127698648,0.00182144384680851,"*",0.00053592,"HIC1","GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0000785//chromatin","GO:0046872//metal ion binding;GO:0042826//histone deacetylase binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0001227//transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0006355//regulation of transcription, DNA-templated;GO:0030178//negative regulation of Wnt signaling pathway;GO:0007275//multicellular organism development;GO:0016055//Wnt signaling pathway;GO:0006351//transcription, DNA-templated;GO:0043517//positive regulation of DNA damage response, signal transduction by p53 class mediator","K09228//KRAB domain-containing zinc finger protein","NP_001091672.1//hypermethylated in cancer 1 protein isoform 2 [Homo sapiens];XP_014973701.1//PREDICTED: hypermethylated in cancer 1 protein isoform X1 [Macaca mulatta]","1//3;3//A2MP1"]
[10420,2973,0.11,0.49,2.15527822547791,7.61784294227188E-3,"*",0.0025609,"TESK2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0005737//cytoplasm","GO:0004713//protein tyrosine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0046872//metal ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0004871//signal transducer activity","GO:0030036//actin cytoskeleton organization;GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction;GO:0007283//spermatogenesis;GO:0048041//focal adhesion assembly","K08842//testis-specific kinase 2 [EC:2.7.12.1]","NP_009101.2//dual specificity testis-specific protein kinase 2 isoform 1 [Homo sapiens]","1//3;2//1"]
[283710,1044,0.16,0.71,2.14974711950468,0.0842359918412348,"*",0.0382632,"LOC283710","NA","NA","NA","NA","NP_001230467.1//uncharacterized protein LOC283710 [Homo sapiens]","2//1"]
[1907,1168,0.71,3.15,2.1494608988826,{"v":2.50259711103228e-06,"d":"2.50E-06"},"Up",{"v":4.41644e-07,"d":"4.42E-07"},"EDN2","GO:0005615//extracellular space;GO:0005622//intracellular;GO:0005576//extracellular region","GO:0031708//endothelin B receptor binding;GO:0005179//hormone activity","GO:0001659//temperature homeostasis;GO:0019229//regulation of vasoconstriction;GO:0042310//vasoconstriction;GO:0007166//cell surface receptor signaling pathway;GO:0097009//energy homeostasis;GO:0014826//vein smooth muscle contraction;GO:0048016//inositol phosphate-mediated signaling;GO:0048246//macrophage chemotaxis;GO:0003058//hormonal regulation of the force of heart contraction;GO:0001516//prostaglandin biosynthetic process;GO:0060585//positive regulation of prostaglandin-endoperoxide synthase activity;GO:0010460//positive regulation of heart rate;GO:0030593//neutrophil chemotaxis;GO:0003100//regulation of systemic arterial blood pressure by endothelin;GO:0042116//macrophage activation;GO:0019722//calcium-mediated signaling;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0045987//positive regulation of smooth muscle contraction;GO:0003099//positive regulation of the force of heart contraction by chemical signal;GO:0014824//artery smooth muscle contraction;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0048286//lung alveolus development;GO:0019221//cytokine-mediated signaling pathway;GO:0008284//positive regulation of cell proliferation","K16367//endothelin-2","XP_524683.3//PREDICTED: endothelin-2 isoform X1 [Pan troglodytes]","4;1//3"]
[286256,694,0.36,1.58,2.13385574673479,0.0316458693782465,"*",0.01258584,"LCN12","GO:0005576//extracellular region","GO:0001972//retinoic acid binding;GO:0005215//transporter activity","GO:0015909//long-chain fatty acid transport;GO:0006629//lipid metabolic process","K21129//lipocalin 2;K03999//complement component 8 subunit gamma;K11454//chromobox protein 7","NP_848631.2//epididymal-specific lipocalin-12 precursor [Homo sapiens]","3//A2MP1"]
[375607,2953,0.03,0.13,2.11547721741994,0.22704220448,"*",0.1243658,"NAT16","NA","NA","NA","K10798//poly [ADP-ribose] polymerase [EC:2.4.2.30];K03129//transcription initiation factor TFIID subunit 4;K14456//2-acylglycerol O-acyltransferase 3 [EC:2.3.1.20 2.3.1.22]","EAW50202.1//FLJ39237 protein [Homo sapiens]","2//1"]
[130940,1226,0.03,0.13,2.11547721741994,0.355739118380699,"*",0.217844,"CCDC148","NA","NA","NA","K12875//apoptotic chromatin condensation inducer in the nucleus","XP_009441804.2//PREDICTED: coiled-coil domain-containing protein 148 isoform X6 [Pan troglodytes];AAM49716.1//unknown [Homo sapiens];NP_620158.3//coiled-coil domain-containing protein 148 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[100128908,2590,0.03,0.13,2.11547721741994,0.355593711015737,"*",0.217844,"LMLN2","NA","NA","NA","K13539//leishmanolysin-like peptidase [EC:3.4.24.-]","NP_001341569.1//leishmanolysin like peptidase 2 precursor [Homo sapiens]","1//3"]
[91319,3115,0.07,0.3,2.09953567355091,0.255285180434064,"*",0.1450622,"DERL3","GO:0030176//integral component of endoplasmic reticulum membrane;GO:0048500//signal recognition particle;GO:0005785//signal recognition particle receptor complex","NA","GO:0018279//protein N-linked glycosylation via asparagine;GO:0030433//ubiquitin-dependent ERAD pathway;GO:1904153//negative regulation of retrograde protein transport, ER to cytosol;GO:0030968//endoplasmic reticulum unfolded protein response","K13989//Derlin-2/3","XP_019292971.1//PREDICTED: derlin-3 isoform X2 [Panthera pardus];XP_012309533.1//derlin-3 isoform X1 [Aotus nancymaae];XP_015102581.1//PREDICTED: derlin-3 isoform X5 [Vicugna pacos]","1//3;3//A2MP1;2//1"]
[80833,2266,0.07,0.3,2.09953567355091,0.131606716804058,"*",0.064963,"APOL3","GO:0016020//membrane;GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0005319//lipid transporter activity;GO:0008289//lipid binding;GO:0004871//signal transducer activity","GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0006869//lipid transport;GO:0042157//lipoprotein metabolic process;GO:0006954//inflammatory response","K14480//apolipoprotein L","NP_055164.1//apolipoprotein L3 isoform 2 [Homo sapiens];NP_663615.1//apolipoprotein L3 isoform 1 [Homo sapiens]","1//3;2//1"]
[84519,1886,0.04,0.17,2.08746284125034,0.355666399836468,"*",0.217844,"ACRBP","GO:0005634//nucleus;GO:0005576//extracellular region;GO:0001669//acrosomal vesicle;GO:0002080//acrosomal membrane","NA","GO:0048240//sperm capacitation","K04574//neurofilament heavy polypeptide;K16751//C2 domain-containing protein 3","NP_115878.2//acrosin-binding protein precursor [Homo sapiens]","2//1"]
[4665,2690,10.56,44.5,2.07519550138267,{"v":1.14878922666667E-167,"d":"1.15E-167"},"Up",{"v":3.02048E-170,"d":"3.02E-170"},"NAB2","GO:0005634//nucleus","GO:0003714//transcription corepressor activity;GO:0042802//identical protein binding;GO:0008134//transcription factor binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0007399//nervous system development;GO:0042552//myelination;GO:0001958//endochondral ossification;GO:0006351//transcription, DNA-templated;GO:0045682//regulation of epidermis development;GO:0016480//negative regulation of transcription from RNA polymerase III promoter;GO:0014037//Schwann cell differentiation;GO:0008283//cell proliferation;GO:1902949//positive regulation of tau-protein kinase activity","NA","XP_020018846.1//NGFI-A-binding protein 2 [Castor canadensis]","1//3;3//A2MP1"]
[2819,3083,0.05,0.21,2.0703893278914,0.131623409690512,"*",0.064963,"GPD1","GO:0070062//extracellular exosome;GO:0009331//glycerol-3-phosphate dehydrogenase complex;GO:0005829//cytosol;GO:0005739//mitochondrion","GO:0051287//NAD binding;GO:0042803//protein homodimerization activity;GO:0004368//glycerol-3-phosphate dehydrogenase activity;GO:0004367//glycerol-3-phosphate dehydrogenase [NAD+] activity","GO:0006127//glycerophosphate shuttle;GO:0046486//glycerolipid metabolic process;GO:0046168//glycerol-3-phosphate catabolic process;GO:0006094//gluconeogenesis;GO:0071356//cellular response to tumor necrosis factor;GO:0071320//cellular response to cAMP;GO:0006654//phosphatidic acid biosynthetic process;GO:0045821//positive regulation of glycolytic process","K00006//glycerol-3-phosphate dehydrogenase (NAD+) [EC:1.1.1.8]","XP_007179402.1//PREDICTED: glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic [Balaenoptera acutorostrata scammoni]","1//3;3//A2MP1"]
[3274,3095,0.12,0.5,2.05889368905357,0.0121094229026549,"*",0.0042831,"HRH2","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004969//histamine receptor activity","GO:0008542//visual learning;GO:0001697//histamine-induced gastric acid secretion;GO:0048732//gland development;GO:0003382//epithelial cell morphogenesis;GO:0001698//gastrin-induced gastric acid secretion;GO:0048565//digestive tract development;GO:0007613//memory;GO:0045907//positive regulation of vasoconstriction;GO:1901998//toxin transport;GO:0006955//immune response;GO:0001696//gastric acid secretion;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0048167//regulation of synaptic plasticity","K04150//histamine receptor H2","NP_001124527.1//histamine H2 receptor isoform 1 [Homo sapiens];XP_018884165.1//PREDICTED: histamine H2 receptor isoform X3 [Gorilla gorilla gorilla]","1//3;2//1"]
[84875,3548,0.2,0.83,2.05311133645956,1.04737679219724E-4,"Up",{"v":2.4201e-05,"d":"2.42E-05"},"PARP10","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0070530//K63-linked polyubiquitin modification-dependent protein binding;GO:0003950//NAD+ ADP-ribosyltransferase activity","GO:0010847//regulation of chromatin assembly;GO:0033159//negative regulation of protein import into nucleus, translocation;GO:0034356//NAD biosynthesis via nicotinamide riboside salvage pathway;GO:0070212//protein poly-ADP-ribosylation;GO:0010629//negative regulation of gene expression;GO:0048147//negative regulation of fibroblast proliferation;GO:0045071//negative regulation of viral genome replication;GO:0070213//protein auto-ADP-ribosylation;GO:1900045//negative regulation of protein K63-linked ubiquitination;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0006471//protein ADP-ribosylation","K15261//poly [ADP-ribose] polymerase 10/14/15 [EC:2.4.2.30]","NP_001304824.1//poly [ADP-ribose] polymerase 10 isoform 2 [Homo sapiens]","4;1//3"]
[183,2587,0.09,0.37,2.03952836418664,0.049771844983723,"*",0.0210566,"AGT","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0072562//blood microparticle;GO:0005829//cytosol;GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0031702//type 1 angiotensin receptor binding;GO:0008083//growth factor activity;GO:0031703//type 2 angiotensin receptor binding;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0048018//receptor ligand activity;GO:0005179//hormone activity","GO:0032930//positive regulation of superoxide anion generation;GO:1905010//positive regulation of L-lysine import across plasma membrane;GO:0045777//positive regulation of blood pressure;GO:0071260//cellular response to mechanical stimulus;GO:1905589//positive regulation of L-arginine import across plasma membrane;GO:0003331//positive regulation of extracellular matrix constituent secretion;GO:0007166//cell surface receptor signaling pathway;GO:0070371//ERK1 and ERK2 cascade;GO:1904707//positive regulation of vascular smooth muscle cell proliferation;GO:0014873//response to muscle activity involved in regulation of muscle adaptation;GO:1904754//positive regulation of vascular associated smooth muscle cell migration;GO:0007565//female pregnancy;GO:0035411//catenin import into nucleus;GO:0048144//fibroblast proliferation;GO:0048146//positive regulation of fibroblast proliferation;GO:0070471//uterine smooth muscle contraction;GO:0003051//angiotensin-mediated drinking behavior;GO:0007202//activation of phospholipase C activity;GO:0014824//artery smooth muscle contraction;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0051403//stress-activated MAPK cascade;GO:0002018//renin-angiotensin regulation of aldosterone production;GO:2001275//positive regulation of glucose import in response to insulin stimulus;GO:0050663//cytokine secretion;GO:0034104//negative regulation of tissue remodeling;GO:0051924//regulation of calcium ion transport;GO:0038166//angiotensin-activated signaling pathway;GO:0002003//angiotensin maturation;GO:0006883//cellular sodium ion homeostasis;GO:0010666//positive regulation of cardiac muscle cell apoptotic process;GO:0042311//vasodilation;GO:0048659//smooth muscle cell proliferation;GO:0051969//regulation of transmission of nerve impulse;GO:0030308//negative regulation of cell growth;GO:0007186//G-protein coupled receptor signaling pathway;GO:0016525//negative regulation of angiogenesis;GO:0002027//regulation of heart rate;GO:0007568//aging;GO:0010613//positive regulation of cardiac muscle hypertrophy;GO:0061049//cell growth involved in cardiac muscle cell development;GO:0035815//positive regulation of renal sodium excretion;GO:0003081//regulation of systemic arterial blood pressure by renin-angiotensin;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0014061//regulation of norepinephrine secretion","K09821//angiotensinogen","BAD93006.1//angiotensinogen precursor variant, partial [Homo sapiens]","3//A2MP1"]
[8542,2884,4.09,16.57,2.0184008542797,{"v":1.01858211e-63,"d":"1.02E-63"},"Up",{"v":1.02024e-65,"d":"1.02E-65"},"APOL1","NA","NA","NA","K14480//apolipoprotein L","NP_663318.1//apolipoprotein L1 isoform b precursor [Homo sapiens];AAI42721.1//APOL1 protein, partial [Homo sapiens]","1//3;3//A2MP1;2//1"]
[144347,2160,0.01,0.04,2,0.65593163564552,"*",0.499032,"RFLNA","GO:0032432//actin filament bundle","GO:0031005//filamin binding","GO:1900158//negative regulation of bone mineralization involved in bone maturation;GO:0061182//negative regulation of chondrocyte development;GO:0048705//skeletal system morphogenesis;GO:0061572//actin filament bundle organization","NA","Q6ZTI6.3//RecName: Full=Refilin-A; AltName: Full=Regulator of filamin protein A; Short=RefilinA",4]
[266629,2230,0.01,0.04,2,0.655877667270034,"*",0.499032,"SEC14L3","GO:0070062//extracellular exosome;GO:0005622//intracellular;GO:0016021//integral component of membrane","GO:0005215//transporter activity","NA","K21954//FYVE and coiled-coil domain-containing protein 1;K01019//galactosylceramide sulfotransferase [EC:2.8.2.11];K19625//retinaldehyde-binding protein 1;K17981//mitochondrial fission process protein 1","XP_002915610.1//PREDICTED: SEC14-like protein 3 [Ailuropoda melanoleuca]","1//3;4"]
[55784,4358,0.01,0.04,2,0.227135796322942,"*",0.1245166,"MCTP2","GO:0016020//membrane;GO:0005654//nucleoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0016021//integral component of membrane","GO:0005509//calcium ion binding","GO:0007275//multicellular organism development;GO:0019722//calcium-mediated signaling","K20045//intersectin","NP_001153115.1//multiple C2 and transmembrane domain-containing protein 2 isoform 2 [Homo sapiens];XP_003268576.2//PREDICTED: multiple C2 and transmembrane domain-containing protein 2 isoform X1 [Nomascus leucogenys];XP_011520075.1//PREDICTED: multiple C2 and transmembrane domain-containing protein 2 isoform X4 [Homo sapiens]","1//3;3//A2MP1"]
[84203,1972,0.01,0.04,2,0.655176885674365,"*",0.499032,"TXNDC2","GO:0005623//cell;GO:0005737//cytoplasm","GO:0047134//protein-disulfide reductase activity;GO:0015035//protein disulfide oxidoreductase activity;GO:0016671//oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor;GO:0004791//thioredoxin-disulfide reductase activity","GO:0006662//glycerol ether metabolic process;GO:0030154//cell differentiation;GO:0007275//multicellular organism development;GO:0034599//cellular response to oxidative stress;GO:0007283//spermatogenesis;GO:0045454//cell redox homeostasis","K03006//DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]","NP_001091999.1//thioredoxin domain-containing protein 2 isoform 2 [Homo sapiens]","1//3;5"]
[10990,1972,0.01,0.04,2,0.654746379301848,"*",0.499032,"LILRB5","GO:0016021//integral component of membrane","GO:0004888//transmembrane signaling receptor activity","GO:0006952//defense response;GO:0007166//cell surface receptor signaling pathway;GO:0002250//adaptive immune response","K06512//leukocyte immunoglobulin-like receptor","NP_001074911.1//leukocyte immunoglobulin-like receptor subfamily B member 5 isoform 1 precursor [Homo sapiens];NP_001074912.1//leukocyte immunoglobulin-like receptor subfamily B member 5 isoform 3 precursor [Homo sapiens];NP_001291386.1//leukocyte immunoglobulin-like receptor subfamily B member 5 isoform 4 precursor [Homo sapiens];NP_006831.1//leukocyte immunoglobulin-like receptor subfamily B member 5 isoform 2 precursor [Homo sapiens]","1//3;4;2//1"]
[120935,1972,0.01,0.04,2,0.654423870618176,"*",0.499032,"CCDC38","GO:0005813//centrosome;GO:0005737//cytoplasm","NA","NA","K17455//fascin 1/2;K01468//imidazolonepropionase [EC:3.5.2.7];K20478//golgin subfamily B member 1;K04345//protein kinase A [EC:2.7.11.11]","NP_872302.2//coiled-coil domain-containing protein 38 [Homo sapiens]","2//1"]
[2912,3364,0.01,0.04,2,0.654316438315686,"*",0.499032,"GRM2","GO:0030425//dendrite;GO:0030424//axon;GO:0005622//intracellular;GO:0030054//cell junction;GO:0043005//neuron projection;GO:0005887//integral component of plasma membrane;GO:0042734//presynaptic membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0008066//glutamate receptor activity;GO:0005246//calcium channel regulator activity;GO:0001641//group II metabotropic glutamate receptor activity;GO:0004930//G-protein coupled receptor activity","GO:0051966//regulation of synaptic transmission, glutamatergic;GO:0007194//negative regulation of adenylate cyclase activity;GO:0007216//G-protein coupled glutamate receptor signaling pathway;GO:0007268//chemical synaptic transmission;GO:0014047//glutamate secretion","K04605//metabotropic glutamate receptor 2/3","XP_017810909.1//metabotropic glutamate receptor 2 isoform X1 [Papio anubis];BAD92401.1//glutamate receptor homolog, partial [Homo sapiens];XP_016796687.1//PREDICTED: metabotropic glutamate receptor 2 isoform X2 [Pan troglodytes]","1//3;4"]
[4110,1892,0.01,0.04,2,0.653994352941176,"*",0.499032,"MAGEA11","GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0005829//cytosol","NA","NA","K12464//melanoma-associated antigen D1","NP_001011544.1//melanoma-associated antigen 11 isoform b [Homo sapiens];NP_005357.2//melanoma-associated antigen 11 isoform a [Homo sapiens]","1//3;4"]
[1041,2583,0.03,0.12,2,0.356285456742091,"*",0.217844,"CDSN","GO:0070062//extracellular exosome;GO:0001533//cornified envelope;GO:0005911//cell-cell junction;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0030057//desmosome","GO:0042803//protein homodimerization activity","GO:0043589//skin morphogenesis;GO:0030216//keratinocyte differentiation;GO:0003336//corneocyte desquamation;GO:0070268//cornification;GO:0098609//cell-cell adhesion;GO:0007155//cell adhesion;GO:0008544//epidermis development;GO:1905716//negative regulation of cornification","K22022//mucin-21;K22020//mucin-19;K12374//arylsulfatase D/F/H [EC:3.1.6.-]","NP_001255.3//corneodesmosin precursor [Homo sapiens]",4]
[3882,2005,0.01,0.04,2,0.65377980546215,"*",0.499032,"KRT32","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0005882//intermediate filament","GO:0005198//structural molecule activity","GO:0008544//epidermis development;GO:0031424//keratinization;GO:0070268//cornification","K07604//type I keratin, acidic","NP_002269.3//keratin, type I cuticular Ha2 [Homo sapiens]","3//A2MP1"]
[286204,5645,0.01,0.04,2,0.227058010091324,"*",0.1245166,"CRB2","GO:0070062//extracellular exosome;GO:0045121//membrane raft;GO:0016324//apical plasma membrane;GO:0043234//protein complex;GO:0016021//integral component of membrane","GO:0005509//calcium ion binding;GO:0019899//enzyme binding","GO:0010951//negative regulation of endopeptidase activity;GO:0010470//regulation of gastrulation;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0030513//positive regulation of BMP signaling pathway;GO:0014028//notochord formation;GO:0001707//mesoderm formation;GO:0072358//cardiovascular system development;GO:0055111//ingression involved in gastrulation with mouth forming second;GO:0001756//somitogenesis;GO:0045199//maintenance of epithelial cell apical/basal polarity","K16681//protein crumbs","NP_775960.4//protein crumbs homolog 2 precursor [Homo sapiens]",6]
[24141,1927,0.01,0.04,2,0.653190525073746,"*",0.499032,"LAMP5","GO:0010008//endosome membrane;GO:0030054//cell junction;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0032584//growth cone membrane;GO:0055038//recycling endosome membrane;GO:0031901//early endosome membrane;GO:0032590//dendrite membrane;GO:0030672//synaptic vesicle membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0030659//cytoplasmic vesicle membrane","NA","NA","K09228//KRAB domain-containing zinc finger protein;K06528//lysosomal-associated membrane protein 1/2","NP_036393.1//lysosome-associated membrane glycoprotein 5 isoform 1 precursor [Homo sapiens];NP_001186826.1//lysosome-associated membrane glycoprotein 5 isoform 2 precursor [Homo sapiens]","1//3;3//A2MP1"]
[5008,1876,0.01,0.04,2,0.652923021377672,"*",0.499032,"OSM","GO:0005615//extracellular space;GO:0005622//intracellular;GO:0005576//extracellular region","GO:0008083//growth factor activity;GO:0005125//cytokine activity;GO:0005147//oncostatin-M receptor binding","GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0002675//positive regulation of acute inflammatory response;GO:0040008//regulation of growth;GO:0051781//positive regulation of cell division;GO:0045835//negative regulation of meiotic nuclear division;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0008283//cell proliferation;GO:0008285//negative regulation of cell proliferation;GO:0007260//tyrosine phosphorylation of STAT protein;GO:0038165//oncostatin-M-mediated signaling pathway;GO:0046888//negative regulation of hormone secretion;GO:0009408//response to heat;GO:2001235//positive regulation of apoptotic signaling pathway;GO:0048266//behavioral response to pain;GO:0007275//multicellular organism development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006955//immune response;GO:0043410//positive regulation of MAPK cascade;GO:0007422//peripheral nervous system development;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0008284//positive regulation of cell proliferation","K05418//oncostatin M","NP_065391.1//oncostatin-M isoform 1 preproprotein [Homo sapiens]","1//3;5"]
[7471,2284,0.01,0.04,2,0.652816081238228,"*",0.499032,"WNT1","GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0009986//cell surface;GO:0030666//endocytic vesicle membrane;GO:0005737//cytoplasm;GO:0005578//proteinaceous extracellular matrix","GO:0019904//protein domain specific binding;GO:0005125//cytokine activity;GO:0005102//receptor binding;GO:0044212//transcription regulatory region DNA binding;GO:0016015//morphogen activity;GO:0005109//frizzled binding","GO:0031100//animal organ regeneration;GO:0045747//positive regulation of Notch signaling pathway;GO:0022004//midbrain-hindbrain boundary maturation during brain development;GO:0021527//spinal cord association neuron differentiation;GO:0043568//positive regulation of insulin-like growth factor receptor signaling pathway;GO:0022408//negative regulation of cell-cell adhesion;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0042472//inner ear morphogenesis;GO:1990403//embryonic brain development;GO:0009611//response to wounding;GO:0000578//embryonic axis specification;GO:1903204//negative regulation of oxidative stress-induced neuron death;GO:0048146//positive regulation of fibroblast proliferation;GO:0045599//negative regulation of fat cell differentiation;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0042770//signal transduction in response to DNA damage;GO:0010592//positive regulation of lamellipodium assembly;GO:0007275//multicellular organism development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0016055//Wnt signaling pathway;GO:2000059//negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0030514//negative regulation of BMP signaling pathway;GO:1904886//beta-catenin destruction complex disassembly;GO:0033278//cell proliferation in midbrain;GO:0033077//T cell differentiation in thymus;GO:0021797//forebrain anterior/posterior pattern specification;GO:0071425//hematopoietic stem cell proliferation;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0044336//canonical Wnt signaling pathway involved in negative regulation of apoptotic process;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:1904954//canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation;GO:0061184//positive regulation of dermatome development;GO:0001934//positive regulation of protein phosphorylation;GO:0060061//Spemann organizer formation;GO:0021588//cerebellum formation;GO:0045165//cell fate commitment;GO:0060348//bone development;GO:0030182//neuron differentiation;GO:0007520//myoblast fusion;GO:0021536//diencephalon development;GO:0090344//negative regulation of cell aging;GO:0048664//neuron fate determination;GO:0030579//ubiquitin-dependent SMAD protein catabolic process;GO:0010812//negative regulation of cell-substrate adhesion;GO:0021551//central nervous system morphogenesis;GO:0036520//astrocyte-dopaminergic neuron signaling","K03209//wingless-type MMTV integration site family, member 1","NP_005421.1//proto-oncogene Wnt-1 precursor [Homo sapiens]","3//A2MP1"]
[9547,1989,0.01,0.04,2,0.652762624303963,"*",0.499032,"CXCL14","NA","NA","NA","K10033//C-X-C motif chemokine 14","EAW62211.1//hCG39697, isoform CRA_a, partial [Homo sapiens]",4]
[4168,3867,0.01,0.04,2,0.394951683792898,"*",0.249274,"MCF2","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005856//cytoskeleton;GO:0005829//cytosol","GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005089//Rho guanyl-nucleotide exchange factor activity","GO:0043065//positive regulation of apoptotic process;GO:1990830//cellular response to leukemia inhibitory factor;GO:0016358//dendrite development;GO:0035023//regulation of Rho protein signal transduction;GO:0035556//intracellular signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction","K20685//guanine nucleotide exchange factor MCF2","XP_005262470.1//PREDICTED: proto-oncogene DBL isoform X2 [Homo sapiens];NP_001165348.1//proto-oncogene DBL isoform d [Homo sapiens];NP_005360.3//proto-oncogene DBL isoform b [Homo sapiens];NP_001165350.1//proto-oncogene DBL isoform f [Homo sapiens];NP_001165349.1//proto-oncogene DBL isoform e [Homo sapiens]","4;1//3"]
[9699,7097,0.01,0.04,2,0.226980277119708,"*",0.1245166,"RIMS2","GO:0070062//extracellular exosome;GO:0048786//presynaptic active zone;GO:0042734//presynaptic membrane;GO:0005622//intracellular;GO:0030054//cell junction","GO:0046872//metal ion binding;GO:0044325//ion channel binding;GO:0017137//Rab GTPase binding","GO:2000300//regulation of synaptic vesicle exocytosis;GO:0048791//calcium ion-regulated exocytosis of neurotransmitter;GO:0010628//positive regulation of gene expression;GO:0030073//insulin secretion;GO:0017156//calcium ion regulated exocytosis;GO:0097151//positive regulation of inhibitory postsynaptic potential;GO:2000463//positive regulation of excitatory postsynaptic potential;GO:0019933//cAMP-mediated signaling;GO:0006886//intracellular protein transport;GO:0017157//regulation of exocytosis;GO:1903861//positive regulation of dendrite extension;GO:0061669//spontaneous neurotransmitter secretion;GO:0042391//regulation of membrane potential","K15297//regulating synaptic membrane exocytosis protein 2","NP_001335432.1//regulating synaptic membrane exocytosis protein 2 isoform x [Homo sapiens];NP_001335417.1//regulating synaptic membrane exocytosis protein 2 isoform i [Homo sapiens];NP_001335436.1//regulating synaptic membrane exocytosis protein 2 isoform bb [Homo sapiens];NP_001335434.1//regulating synaptic membrane exocytosis protein 2 isoform z [Homo sapiens];NP_001335433.1//regulating synaptic membrane exocytosis protein 2 isoform y [Homo sapiens];NP_001335415.1//regulating synaptic membrane exocytosis protein 2 isoform g [Homo sapiens];NP_001335416.1//regulating synaptic membrane exocytosis protein 2 isoform h [Homo sapiens];NP_001335427.1//regulating synaptic membrane exocytosis protein 2 isoform s [Homo sapiens];NP_001335429.1//regulating synaptic membrane exocytosis protein 2 isoform u [Homo sapiens];NP_001335422.1//regulating synaptic membrane exocytosis protein 2 isoform n [Homo sapiens];XP_005613300.1//PREDICTED: regulating synaptic membrane exocytosis protein 2 isoform X6 [Equus caballus];NP_001335431.1//regulating synaptic membrane exocytosis protein 2 isoform w [Homo sapiens];NP_001335424.1//regulating synaptic membrane exocytosis protein 2 isoform p [Homo sapiens];NP_001335414.1//regulating synaptic membrane exocytosis protein 2 isoform f [Homo sapiens];NP_001335421.1//regulating synaptic membrane exocytosis protein 2 isoform m [Homo sapiens];NP_055492.3//regulating synaptic membrane exocytosis protein 2 isoform b [Homo sapiens];NP_001335418.1//regulating synaptic membrane exocytosis protein 2 isoform j [Homo sapiens];NP_001269810.1//regulating synaptic membrane exocytosis protein 2 isoform c [Homo sapiens];NP_001335430.1//regulating synaptic membrane exocytosis protein 2 isoform v [Homo sapiens];NP_001335413.1//regulating synaptic membrane exocytosis protein 2 isoform e [Homo sapiens];NP_001093587.1//regulating synaptic membrane exocytosis protein 2 isoform a [Homo sapiens];NP_001335423.1//regulating synaptic membrane exocytosis protein 2 isoform o [Homo sapiens];NP_001335426.1//regulating synaptic membrane exocytosis protein 2 isoform r [Homo sapiens];NP_001335435.1//regulating synaptic membrane exocytosis protein 2 isoform aa [Homo sapiens];NP_001335420.1//regulating synaptic membrane exocytosis protein 2 isoform l [Homo sapiens];NP_001335437.1//regulating synaptic membrane exocytosis protein 2 isoform cc [Homo sapiens];NP_001335438.1//regulating synaptic membrane exocytosis protein 2 isoform dd [Homo sapiens];NP_001335428.1//regulating synaptic membrane exocytosis protein 2 isoform t [Homo sapiens];NP_001335425.1//regulating synaptic membrane exocytosis protein 2 isoform q [Homo sapiens];NP_001335419.1//regulating synaptic membrane exocytosis protein 2 isoform k [Homo sapiens]","4;1//3;2//1"]
[442247,1900,0.01,0.04,2,0.65206848,"*",0.499032,"RFPL4B","NA","GO:0046872//metal ion binding","NA","K12009//tripartite motif-containing protein 27 [EC:2.3.2.27];K10651//tripartite motif-containing protein 21 [EC:2.3.2.27]","NP_001013756.2//ret finger protein-like 4B [Homo sapiens]","2//1"]
[56606,1874,0.01,0.04,2,0.651429040451091,"*",0.499032,"SLC2A9","GO:0016021//integral component of membrane","NA","GO:0008643//carbohydrate transport","K08146//MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 9","XP_008991848.2//PREDICTED: solute carrier family 2, facilitated glucose transporter member 9 isoform X2 [Callithrix jacchus];XP_016806815.1//PREDICTED: solute carrier family 2, facilitated glucose transporter member 9 isoform X4 [Pan troglodytes]","1//3;2//1"]
[65997,1979,0.01,0.04,2,0.650366090234152,"*",0.499032,"RASL11B","GO:0016020//membrane","GO:0005525//GTP binding;GO:0005160//transforming growth factor beta receptor binding;GO:0003924//GTPase activity","GO:0007165//signal transduction;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway","K07853//Ras-like protein family member 11B","NP_076429.1//ras-like protein family member 11B [Homo sapiens]","2//1"]
[220441,1805,0.01,0.04,2,0.650047881268857,"*",0.499032,"RNF152","GO:0005765//lysosomal membrane;GO:0031301//integral component of organelle membrane;GO:0016021//integral component of membrane;GO:0005764//lysosome","GO:0031267//small GTPase binding;GO:0061630//ubiquitin protein ligase activity;GO:0046872//metal ion binding;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity","GO:0070534//protein K63-linked ubiquitination;GO:0070936//protein K48-linked ubiquitination;GO:0034198//cellular response to amino acid starvation;GO:0016567//protein ubiquitination;GO:0010508//positive regulation of autophagy;GO:1904262//negative regulation of TORC1 signaling;GO:0006915//apoptotic process;GO:0000209//protein polyubiquitination","K15705//E3 ubiquitin-protein ligase RNF152 [EC:2.3.2.27]","XP_020040697.1//E3 ubiquitin-protein ligase RNF152 [Castor canadensis]","2//1"]
[89866,4347,0.01,0.04,2,0.393974757692688,"*",0.249274,"SEC16B","GO:0043231//intracellular membrane-bounded organelle;GO:0005829//cytosol;GO:0005789//endoplasmic reticulum membrane;GO:0000139//Golgi membrane","NA","GO:0007031//peroxisome organization;GO:0048208//COPII vesicle coating;GO:0015031//protein transport;GO:0010628//positive regulation of gene expression;GO:0070863//positive regulation of protein exit from endoplasmic reticulum;GO:0016559//peroxisome fission;GO:0007029//endoplasmic reticulum organization","K20353//COPII coat assembly protein SEC16","NP_149118.2//protein transport protein Sec16B [Homo sapiens];AAH09106.1//SEC16B protein [Homo sapiens]","1//3;3//A2MP1"]
[10164,2145,0.01,0.04,2,0.648830959466059,"*",0.499032,"CHST4","GO:0031228//intrinsic component of Golgi membrane;GO:0016021//integral component of membrane;GO:0005802//trans-Golgi network;GO:0000139//Golgi membrane","GO:0008146//sulfotransferase activity;GO:0001517//N-acetylglucosamine 6-O-sulfotransferase activity","GO:0006790//sulfur compound metabolic process;GO:0006044//N-acetylglucosamine metabolic process;GO:0007267//cell-cell signaling;GO:0006477//protein sulfation;GO:0016266//O-glycan processing;GO:0006954//inflammatory response;GO:0007155//cell adhesion;GO:0018146//keratan sulfate biosynthetic process;GO:0006928//movement of cell or subcellular component;GO:0005975//carbohydrate metabolic process;GO:0006955//immune response","K04746//carbohydrate 6-sulfotransferase 4 [EC:2.8.2.-]","NP_005760.1//carbohydrate sulfotransferase 4 [Homo sapiens]","1//3;2//1"]
[10841,1917,0.01,0.04,2,0.648778153170017,"*",0.499032,"FTCD","GO:0070062//extracellular exosome;GO:0005783//endoplasmic reticulum;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005737//cytoplasm;GO:0000139//Golgi membrane;GO:0005814//centriole;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0030868//smooth endoplasmic reticulum membrane","GO:0030412//formimidoyltetrahydrofolate cyclodeaminase activity;GO:0005542//folic acid binding;GO:0030409//glutamate formimidoyltransferase activity;GO:0008017//microtubule binding;GO:0030407//formimidoyltransferase activity","GO:0019557//histidine catabolic process to glutamate and formate;GO:0006760//folic acid-containing compound metabolic process;GO:0007010//cytoskeleton organization;GO:0035999//tetrahydrofolate interconversion;GO:0006548//histidine catabolic process;GO:0019556//histidine catabolic process to glutamate and formamide","K13990//glutamate formiminotransferase / formiminotetrahydrofolate cyclodeaminase [EC:2.1.2.5 4.3.1.4]","EAX09312.1//formiminotransferase cyclodeaminase, isoform CRA_d, partial [Homo sapiens];EAX09308.1//formiminotransferase cyclodeaminase, isoform CRA_a [Homo sapiens]","1//3;2//1"]
[255877,3544,0.01,0.04,2,0.393546439612572,"*",0.249274,"BCL6B","NA","GO:0003676//nucleic acid binding","NA","K09228//KRAB domain-containing zinc finger protein","KFV50562.1//B-cell lymphoma 6 protein, partial [Gavia stellata]","3//A2MP1"]
[29999,1911,0.01,0.04,2,0.648039766523047,"*",0.499032,"FSCN3","GO:0005856//cytoskeleton;GO:0005902//microvillus;GO:0030027//lamellipodium;GO:0005737//cytoplasm;GO:0030175//filopodium;GO:0001726//ruffle;GO:0031253//cell projection membrane;GO:0030426//growth cone;GO:0015629//actin cytoskeleton;GO:0031941//filamentous actin","GO:0051015//actin filament binding;GO:0030674//protein binding, bridging","GO:0007015//actin filament organization;GO:0016477//cell migration;GO:0009653//anatomical structure morphogenesis;GO:0007163//establishment or maintenance of cell polarity;GO:0051017//actin filament bundle assembly;GO:0007286//spermatid development","K17456//fascin 3","XP_011727897.1//PREDICTED: fascin-3 isoform X2 [Macaca nemestrina]","2//1"]
[55089,3807,0.01,0.04,2,0.39342978717518,"*",0.249274,"SLC38A4","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0015293//symporter activity;GO:0015171//amino acid transmembrane transporter activity","GO:0006865//amino acid transport;GO:0003333//amino acid transmembrane transport;GO:0006814//sodium ion transport","K14991//solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 4","NP_060488.2//sodium-coupled neutral amino acid transporter 4 [Homo sapiens]","1//3;4"]
[7054,1898,0.01,0.04,2,0.647565976279448,"*",0.499032,"TH","GO:0005790//smooth endoplasmic reticulum;GO:0030424//axon;GO:0005634//nucleus;GO:0031410//cytoplasmic vesicle;GO:0033162//melanosome membrane;GO:0005737//cytoplasm;GO:0043204//perikaryon;GO:0005829//cytosol;GO:0009898//cytoplasmic side of plasma membrane","GO:0016597//amino acid binding;GO:0005506//iron ion binding;GO:0004511//tyrosine 3-monooxygenase activity;GO:0008199//ferric iron binding;GO:0035240//dopamine binding;GO:0019899//enzyme binding","GO:0042423//catecholamine biosynthetic process;GO:0007617//mating behavior;GO:0007601//visual perception;GO:0042418//epinephrine biosynthetic process;GO:0045471//response to ethanol;GO:0015842//aminergic neurotransmitter loading into synaptic vesicle;GO:0008016//regulation of heart contraction;GO:0048596//embryonic camera-type eye morphogenesis;GO:0009653//anatomical structure morphogenesis;GO:0042755//eating behavior;GO:0007507//heart development;GO:0006585//dopamine biosynthetic process from tyrosine;GO:0007612//learning;GO:0001666//response to hypoxia;GO:0009887//animal organ morphogenesis;GO:0007626//locomotory behavior;GO:0007613//memory;GO:0042421//norepinephrine biosynthetic process;GO:0001963//synaptic transmission, dopaminergic;GO:0042462//eye photoreceptor cell development","K00501//tyrosine 3-monooxygenase [EC:1.14.16.2]","NP_000351.2//tyrosine 3-monooxygenase isoform b [Homo sapiens];NP_954987.2//tyrosine 3-monooxygenase isoform c [Homo sapiens];NP_954986.2//tyrosine 3-monooxygenase isoform a [Homo sapiens]","3//A2MP1;2//1"]
[154197,1859,0.01,0.04,2,0.647408200113701,"*",0.499032,"PNLDC1","GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0004535//poly(A)-specific ribonuclease activity;GO:0003723//RNA binding;GO:0046872//metal ion binding;GO:0003676//nucleic acid binding","GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","K01148//poly(A)-specific ribonuclease [EC:3.1.13.4]","NP_775787.1//poly(A)-specific ribonuclease PNLDC1 isoform 2 precursor [Homo sapiens];NP_001258791.1//poly(A)-specific ribonuclease PNLDC1 isoform 1 [Homo sapiens]","1//3;2//1"]
[57451,9458,0.01,0.04,2,0.226964388118359,"*",0.1243658,"TENM2","NA","NA","NA","K06252//tenascin","XP_022273430.1//teneurin-2 isoform X2 [Canis lupus familiaris]","1//3;2//1"]
[5579,8014,0.01,0.04,2,0.127590965968923,"*",0.062198,"PRKCB","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0042393//histone binding;GO:0035403//histone kinase activity (H3-T6 specific);GO:0005524//ATP binding;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0004697//protein kinase C activity;GO:0005080//protein kinase C binding;GO:0004674//protein serine/threonine kinase activity;GO:0050681//androgen receptor binding;GO:0003682//chromatin binding;GO:0008270//zinc ion binding;GO:0005246//calcium channel regulator activity;GO:0004698//calcium-dependent protein kinase C activity","GO:0007077//mitotic nuclear envelope disassembly;GO:0050861//positive regulation of B cell receptor signaling pathway;GO:0030168//platelet activation;GO:0035556//intracellular signal transduction;GO:0045637//regulation of myeloid cell differentiation;GO:0035408//histone H3-T6 phosphorylation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0045766//positive regulation of angiogenesis;GO:0042953//lipoprotein transport;GO:0006874//cellular calcium ion homeostasis;GO:0050853//B cell receptor signaling pathway;GO:0007165//signal transduction;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0006468//protein phosphorylation;GO:0030949//positive regulation of vascular endothelial growth factor receptor signaling pathway;GO:0006351//transcription, DNA-templated;GO:0006816//calcium ion transport;GO:0001666//response to hypoxia;GO:0002250//adaptive immune response;GO:0006915//apoptotic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0071322//cellular response to carbohydrate stimulus;GO:0010829//negative regulation of glucose transport;GO:0018105//peptidyl-serine phosphorylation;GO:0042113//B cell activation","K19662//classical protein kinase C beta type [EC:2.7.11.13]","XP_021082023.1//protein kinase C beta type [Mesocricetus auratus];NP_002729.2//protein kinase C beta type isoform 2 [Homo sapiens]","6;2//1"]
[2165,2217,0.01,0.04,2,0.64620113229572,"*",0.499032,"F13B","GO:0005576//extracellular region","NA","GO:0007596//blood coagulation","K03906//coagulation factor XIII B polypeptide","NP_001985.2//coagulation factor XIII B chain precursor [Homo sapiens]","2//1"]
[1393,1854,0.01,0.04,2,0.646096382557951,"*",0.499032,"CRHBP","GO:0030425//dendrite;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0005874//microtubule;GO:0005622//intracellular;GO:0043204//perikaryon;GO:0043196//varicosity;GO:0030141//secretory granule;GO:0005767//secondary lysosome;GO:0031045//dense core granule;GO:0005576//extracellular region;GO:0005771//multivesicular body;GO:0043679//axon terminus","GO:0042277//peptide binding;GO:0051424//corticotropin-releasing hormone binding","GO:0033554//cellular response to stress;GO:0035690//cellular response to drug;GO:0071356//cellular response to tumor necrosis factor;GO:0051459//regulation of corticotropin secretion;GO:0071320//cellular response to cAMP;GO:2000310//regulation of NMDA receptor activity;GO:0097211//cellular response to gonadotropin-releasing hormone;GO:0071277//cellular response to calcium ion;GO:0007611//learning or memory;GO:0009755//hormone-mediated signaling pathway;GO:0035865//cellular response to potassium ion;GO:0048149//behavioral response to ethanol;GO:0007565//female pregnancy;GO:0051460//negative regulation of corticotropin secretion;GO:0007165//signal transduction;GO:0045055//regulated exocytosis;GO:1900011//negative regulation of corticotropin-releasing hormone receptor activity;GO:0071314//cellular response to cocaine;GO:0006954//inflammatory response;GO:0071391//cellular response to estrogen stimulus;GO:0001963//synaptic transmission, dopaminergic;GO:0071392//cellular response to estradiol stimulus","NA","NP_001873.2//corticotropin-releasing factor-binding protein precursor [Homo sapiens]","3//A2MP1"]
[9248,2020,0.01,0.04,2,0.645886984929509,"*",0.499032,"GPR50","GO:0005654//nucleoplasm;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0042802//identical protein binding;GO:0008502//melatonin receptor activity;GO:0004930//G-protein coupled receptor activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0007267//cell-cell signaling","K04287//G protein-coupled receptor 50","NP_004215.2//melatonin-related receptor [Homo sapiens]","3//A2MP1"]
[286234,4471,0.01,0.04,2,0.392808806944855,"*",0.249274,"SPATA31E1","GO:0016021//integral component of membrane","NA","GO:0030154//cell differentiation;GO:0007283//spermatogenesis","NA","NP_849150.3//spermatogenesis-associated protein 31E1 [Homo sapiens]",4]
[7447,2014,0.01,0.04,2,0.645573142857143,"*",0.499032,"VSNL1","NA","GO:0005509//calcium ion binding","NA","K19936//visinin-like protein 1","XP_012975277.1//visinin-like protein 1 isoform X1 [Mesocricetus auratus]",4]
[653509,2075,0.01,0.04,2,0.645364084196891,"*",0.499032,"SFTPA1","NA","NA","NA","K10067//pulmonary surfactant-associated protein A;K06237//collagen, type IV, alpha","XP_019811710.1//PREDICTED: collagen alpha-5(IV) chain isoform X1 [Bos indicus];NP_001158117.1//pulmonary surfactant-associated protein A1 isoform 3 precursor [Homo sapiens]","4;1//3;2//1"]
[1551,2099,0.01,0.04,2,0.645311840686473,"*",0.499032,"CYP3A7","GO:0016021//integral component of membrane","GO:0020037//heme binding;GO:0005506//iron ion binding;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen","NA","K17691//cytochrome P450 family 3 subfamily A polypeptide 7 [EC:1.14.14.1]","XP_016812378.1//PREDICTED: cytochrome P450, family 3, subfamily A, polypeptide 67 isoform X1 [Pan troglodytes]",4]
[55340,1895,0.01,0.04,2,0.644894196909635,"*",0.499032,"GIMAP5","GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane","GO:0005525//GTP binding","NA","K15261//poly [ADP-ribose] polymerase 10/14/15 [EC:2.4.2.30];K18626//trichohyalin","NP_001186506.1//GIMAP1-GIMAP5 protein isoform a [Homo sapiens]",4]
[81551,2234,0.01,0.04,2,0.644842029445074,"*",0.499032,"STMN4","GO:0030424//axon;GO:0030426//growth cone;GO:0005794//Golgi apparatus;GO:0005737//cytoplasm;GO:0043005//neuron projection","GO:0015631//tubulin binding","GO:0031110//regulation of microtubule polymerization or depolymerization;GO:0051493//regulation of cytoskeleton organization;GO:0031175//neuron projection development;GO:0007019//microtubule depolymerization","K12012//tripartite motif-containing protein 35;K04381//stathmin","EDL35996.1//stathmin-like 4, isoform CRA_d [Mus musculus];NP_001069048.1//stathmin-4 [Bos taurus];NP_110422.2//stathmin-4 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[10742,2079,0.01,0.04,2,0.644424993371059,"*",0.499032,"RAI2","NA","NA","GO:0009790//embryo development","K13096//splicing factor 4;K02367//glucuronyl/N-acetylglucosaminyl transferase EXT2 [EC:2.4.1.224 2.4.1.225]","NP_001166203.1//retinoic acid-induced protein 2 isoform 2 [Homo sapiens];NP_068557.3//retinoic acid-induced protein 2 isoform 1 [Homo sapiens]","4;1//3"]
[129852,1921,0.01,0.04,2,0.644216677549701,"*",0.499032,"C2orf73","NA","NA","NA","NA","NP_001093866.1//uncharacterized protein C2orf73 [Homo sapiens]","1//3"]
[220136,1864,0.01,0.04,2,0.644112570135747,"*",0.499032,"CFAP53","NA","NA","GO:0003341//cilium movement;GO:0060271//cilium assembly;GO:0007368//determination of left/right symmetry","K11589//methyl-CpG-binding domain protein 1;K05058//leukemia inhibitory factor receptor;K16811//trichoplein keratin filament-binding protein","XP_003827259.2//PREDICTED: cilia- and flagella-associated protein 53 [Pan paniscus]",4]
[8876,3844,0.02,0.08,2,0.355848251968504,"*",0.217844,"VNN1","GO:0070062//extracellular exosome;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0031225//anchored component of membrane;GO:0035577//azurophil granule membrane","GO:0017159//pantetheine hydrolase activity","GO:1902176//negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:0006501//C-terminal protein lipidation;GO:0033089//positive regulation of T cell differentiation in thymus;GO:0002526//acute inflammatory response;GO:0006954//inflammatory response;GO:0006979//response to oxidative stress;GO:0098609//cell-cell adhesion;GO:0006928//movement of cell or subcellular component;GO:0002544//chronic inflammatory response;GO:0015939//pantothenate metabolic process;GO:0043312//neutrophil degranulation;GO:0045087//innate immune response","K08069//pantetheine hydrolase [EC:3.5.1.92]","NP_004657.2//pantetheinase precursor [Homo sapiens]","2//1"]
[8572,2292,0.01,0.04,2,0.642762229317852,"*",0.499032,"PDLIM4","GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0030027//lamellipodium;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0001725//stress fiber;GO:0034777//recycling endosome lumen;GO:0043197//dendritic spine;GO:0045211//postsynaptic membrane;GO:0031905//early endosome lumen;GO:0031941//filamentous actin","GO:0046872//metal ion binding;GO:0051393//alpha-actinin binding;GO:0019903//protein phosphatase binding;GO:0042803//protein homodimerization activity","GO:0031532//actin cytoskeleton reorganization;GO:0098976//excitatory chemical synaptic transmission","K19867//LIM domain-binding protein 3","NP_001124499.1//PDZ and LIM domain protein 4 isoform 2 [Homo sapiens];NP_003678.2//PDZ and LIM domain protein 4 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[140691,1433,0.01,0.04,2,0.642503197227372,"*",0.499032,"TRIM69","GO:0005634//nucleus;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0004842//ubiquitin-protein transferase activity","GO:0000209//protein polyubiquitination;GO:0006915//apoptotic process","K12034//tripartite motif-containing protein 69 [EC:2.3.2.27]","XP_017716518.1//PREDICTED: E3 ubiquitin-protein ligase TRIM69 isoform X4 [Rhinopithecus bieti];NP_892030.3//E3 ubiquitin-protein ligase TRIM69 isoform a [Homo sapiens];NP_542783.2//E3 ubiquitin-protein ligase TRIM69 isoform b [Homo sapiens];XP_017716517.1//PREDICTED: E3 ubiquitin-protein ligase TRIM69 isoform X3 [Rhinopithecus bieti];NP_001288075.1//E3 ubiquitin-protein ligase TRIM69 isoform e [Homo sapiens]","1//3;4"]
[6005,1953,0.01,0.04,2,0.640901846599132,"*",0.499032,"RHAG","GO:0016020//membrane;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0008519//ammonium transmembrane transporter activity;GO:0022840//leak channel activity;GO:0035379//carbon dioxide transmembrane transporter activity;GO:0030506//ankyrin binding","GO:0015695//organic cation transport;GO:0060586//multicellular organismal iron ion homeostasis;GO:0015670//carbon dioxide transport;GO:0006873//cellular ion homeostasis;GO:0015696//ammonium transport;GO:0015701//bicarbonate transport;GO:0048821//erythrocyte development;GO:0072488//ammonium transmembrane transport;GO:0015672//monovalent inorganic cation transport","K06580//ammonium transporter Rh","NP_000315.2//ammonium transporter Rh type A [Homo sapiens]","2//1"]
[254050,1934,0.01,0.04,2,0.640438432393348,"*",0.499032,"LRRC43","NA","NA","NA","NA","XP_016874613.1//PREDICTED: leucine-rich repeat-containing protein 43 isoform X1 [Homo sapiens];NP_001091989.1//leucine-rich repeat-containing protein 43 isoform 1 [Homo sapiens]","1//3;4"]
[85508,3594,0.01,0.04,2,0.391842440070852,"*",0.249274,"SCRT2","NA","NA","NA","K09219//scratch","XP_016792752.1//PREDICTED: transcriptional repressor scratch 2 [Pan troglodytes]","3//A2MP1"]
[5055,1924,0.01,0.04,2,0.640335542453209,"*",0.499032,"SERPINB2","GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0004867//serine-type endopeptidase inhibitor activity","GO:0042730//fibrinolysis;GO:0042060//wound healing;GO:0043066//negative regulation of apoptotic process;GO:0035722//interleukin-12-mediated signaling pathway","K19821//plasminogen activator inhibitor 2","NP_002566.1//plasminogen activator inhibitor 2 [Homo sapiens]","1//3;2//1"]
[645027,2015,0.01,0.04,2,0.640078462180825,"*",0.499032,"EVPLL","GO:0001533//cornified envelope","GO:0005198//structural molecule activity;GO:0019215//intermediate filament binding","GO:0008544//epidermis development","K10383//envoplakin","NP_001138599.1//envoplakin-like protein [Homo sapiens]","1//3"]
[24,7326,0.01,0.04,2,0.355630051711804,"*",0.217844,"ABCA4","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0097381//photoreceptor disc membrane;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane","GO:0005524//ATP binding;GO:0090555//phosphatidylethanolamine-translocating ATPase activity;GO:0042626//ATPase activity, coupled to transmembrane movement of substances;GO:0005395//eye pigment precursor transporter activity;GO:0005215//transporter activity;GO:0016887//ATPase activity","GO:0006810//transport;GO:0055085//transmembrane transport;GO:0001523//retinoid metabolic process;GO:0007603//phototransduction, visible light;GO:0045332//phospholipid translocation;GO:0006649//phospholipid transfer to membrane;GO:0007601//visual perception;GO:0045494//photoreceptor cell maintenance","K05644//ATP-binding cassette, subfamily A (ABC1), member 4","NP_000341.2//retinal-specific ATP-binding cassette transporter [Homo sapiens]","2//1"]
[719,3555,0.01,0.04,2,0.391803884286136,"*",0.249274,"C3AR1","GO:0005887//integral component of plasma membrane;GO:0005623//cell;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane;GO:0005886//plasma membrane;GO:0035577//azurophil granule membrane","GO:0004876//complement component C3a receptor activity;GO:0004930//G-protein coupled receptor activity","GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway;GO:0030449//regulation of complement activation;GO:0090023//positive regulation of neutrophil chemotaxis;GO:0010575//positive regulation of vascular endothelial growth factor production;GO:0050900//leukocyte migration;GO:0010759//positive regulation of macrophage chemotaxis;GO:0006954//inflammatory response;GO:0008015//blood circulation;GO:0060326//cell chemotaxis;GO:0043312//neutrophil degranulation;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0006935//chemotaxis;GO:0045766//positive regulation of angiogenesis","K04009//C3a anaphylatoxin chemotactic receptor","NP_004045.1//C3a anaphylatoxin chemotactic receptor [Homo sapiens]","1//3;3//A2MP1"]
[158809,1949,0.01,0.04,2,0.639564920410783,"*",0.499032,"MAGEB6","NA","NA","NA","K12464//melanoma-associated antigen D1","NP_775794.2//melanoma-associated antigen B6 [Homo sapiens]","2//1"]
[344787,3210,0.05,0.2,2,0.203124322554984,"*",0.1086958,"ZNF860","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_014987882.1//PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 860 [Macaca mulatta]","2//1"]
[8013,5635,0.45,1.79,1.99196268093458,{"v":6.26535485855263e-14,"d":"6.27E-14"},"Up",{"v":4.76942e-15,"d":"4.77E-15"},"NR4A3","NA","NA","NA","K08559//nuclear receptor subfamily 4 group A member 3","XP_017383295.1//PREDICTED: nuclear receptor subfamily 4 group A member 3 isoform X1 [Cebus capucinus imitator];AAB36006.1//steroid/thyroid orphan receptor homolog gene, partial [Homo sapiens]","3//A2MP1;2//1"]
[161247,1064,0.08,0.31,1.95419631038688,0.355957452536825,"*",0.217844,"FITM1","NA","NA","NA","K09291//nucleoprotein TPR;K11801//WD repeat-containing protein 23","XP_005560985.1//PREDICTED: fat storage-inducing transmembrane protein 1 [Macaca fascicularis]","2//1"]
[146556,1933,0.08,0.31,1.95419631038688,0.0851397958230283,"*",0.038791,"C16orf89","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005829//cytosol","GO:0042803//protein homodimerization activity","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K22069//LYR motif-containing protein 4;K11447//histone demethylase [EC:1.14.11.-];K01064//wingless-type MMTV integration site family, member 9","AAQ88847.1//SARG904 [Homo sapiens];EAW85242.1//hypothetical protein MGC45438, isoform CRA_a [Homo sapiens]","4;2//1"]
[23066,4248,0.28,1.08,1.94753258010586,{"v":5.66631287052342e-07,"d":"5.67E-07"},"Up",{"v":9.01346e-08,"d":"9.01E-08"},"CAND2","GO:0005634//nucleus;GO:0005622//intracellular","GO:0017025//TBP-class protein binding","GO:0010265//SCF complex assembly;GO:0016567//protein ubiquitination;GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated","K17263//cullin-associated NEDD8-dissociated protein 1","XP_011839000.1//PREDICTED: cullin-associated NEDD8-dissociated protein 2 isoform X1 [Mandrillus leucophaeus];NP_036430.1//cullin-associated NEDD8-dissociated protein 2 isoform 2 [Homo sapiens]","1//3;2//1"]
[3112,1388,0.06,0.23,1.93859945533586,0.356139602497186,"*",0.217844,"HLA-DOB","GO:0005765//lysosomal membrane;GO:0010008//endosome membrane;GO:0042613//MHC class II protein complex;GO:0005622//intracellular;GO:0016021//integral component of membrane;GO:0005764//lysosome","GO:0032395//MHC class II receptor activity;GO:0023026//MHC class II protein complex binding","GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0002504//antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;GO:0006955//immune response;GO:0002587//negative regulation of antigen processing and presentation of peptide antigen via MHC class II","K06752//major histocompatibility complex, class II","XP_004043832.1//PREDICTED: HLA class II histocompatibility antigen, DO beta chain [Gorilla gorilla gorilla]","3//A2MP1"]
[5349,1380,0.06,0.23,1.93859945533586,0.356066720147345,"*",0.217844,"FXYD3","GO:0070062//extracellular exosome;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005216//ion channel activity;GO:0017080//sodium channel regulator activity;GO:0005254//chloride channel activity","GO:1903779//regulation of cardiac conduction;GO:0006813//potassium ion transport;GO:2000649//regulation of sodium ion transmembrane transporter activity;GO:0006821//chloride transport;GO:0034220//ion transmembrane transport;GO:0006814//sodium ion transport","K13361//FXYD domain-containing ion transport regulator 3","NP_001129481.1//FXYD domain-containing ion transport regulator 3 isoform 5 precursor [Homo sapiens];NP_001129479.1//FXYD domain-containing ion transport regulator 3 isoform 3 [Homo sapiens];AQN67652.1//FXYD domain-containing ion transport regulator 3 [Homo sapiens];XP_011525334.1//PREDICTED: FXYD domain-containing ion transport regulator 3 isoform X1 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[51129,1905,4.59,17.58,1.9373690117296,{"v":1.62537699859155E-41,"d":"1.63E-41"},"Up",{"v":2.88974e-43,"d":"2.89E-43"},"ANGPTL4","GO:0005615//extracellular space;GO:0072562//blood microparticle;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix","GO:0042802//identical protein binding;GO:0004857//enzyme inhibitor activity","GO:0051005//negative regulation of lipoprotein lipase activity;GO:0030154//cell differentiation;GO:0001525//angiogenesis;GO:0051260//protein homooligomerization;GO:0043066//negative regulation of apoptotic process;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:0001666//response to hypoxia;GO:0070328//triglyceride homeostasis;GO:0019216//regulation of lipid metabolic process;GO:0045766//positive regulation of angiogenesis","K08767//angiopoietin-like 4","AAQ88642.1//NL2 [Homo sapiens]","2//1"]
[374918,771,0.54,2.06,1.93161302501975,0.0114302464991983,"*",0.0040164,"IGFL1","GO:0005615//extracellular space","NA","NA","NA","NP_940943.1//insulin growth factor-like family member 1 precursor [Homo sapiens]","1//3"]
[79689,4532,0.13,0.49,1.91427012597412,2.80891328760972E-3,"*",8.61454E-4,"STEAP4","GO:0070062//extracellular exosome;GO:0005768//endosome;GO:0031901//early endosome membrane;GO:0005887//integral component of plasma membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0000139//Golgi membrane","GO:0008823//cupric reductase activity;GO:0046872//metal ion binding;GO:0052851//ferric-chelate reductase (NADPH) activity","GO:0055072//iron ion homeostasis;GO:0098706//ferric iron import across plasma membrane;GO:0045444//fat cell differentiation;GO:0015677//copper ion import","K19876//metalloreductase STEAP4 [EC:1.16.1.-]","NP_001192245.1//metalloreductase STEAP4 isoform 2 [Homo sapiens];NP_078912.2//metalloreductase STEAP4 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[389289,1280,1.59,5.98,1.91111871891375,{"v":7.11608308022599e-10,"d":"7.12E-10"},"Up",{"v":7.88498e-11,"d":"7.88E-11"},"ANXA2R","NA","GO:0004872//receptor activity","NA","NA","XP_004058948.1//PREDICTED: annexin-2 receptor [Gorilla gorilla gorilla]","2//1"]
[6404,2573,0.19,0.71,1.9018196060611,0.00440197710509804,"*",1.405414E-3,"SELPLG","GO:0016020//membrane;GO:0005887//integral component of plasma membrane;GO:0044853//plasma membrane raft;GO:0016021//integral component of membrane;GO:0001931//uropod;GO:0005886//plasma membrane","GO:0005102//receptor binding;GO:0001618//virus receptor activity","GO:0007155//cell adhesion;GO:0071354//cellular response to interleukin-6;GO:0050900//leukocyte migration;GO:0050902//leukocyte adhesive activation;GO:0050901//leukocyte tethering or rolling","K06544//selectin P ligand","NP_001193538.1//P-selectin glycoprotein ligand 1 isoform 1 precursor [Homo sapiens]","4;1//3"]
[23308,3013,0.93,3.47,1.89963304147023,{"v":3.93209515731874E-8,"d":"3.93E-08"},"Up",{"v":5.3982e-09,"d":"5.40E-09"},"ICOSLG","GO:0070062//extracellular exosome;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005102//receptor binding","GO:0042110//T cell activation;GO:0007165//signal transduction;GO:0031295//T cell costimulation;GO:0002250//adaptive immune response;GO:0006972//hyperosmotic response;GO:0006952//defense response;GO:0042113//B cell activation;GO:0042104//positive regulation of activated T cell proliferation","K06710//inducible T-cell co-stimulator ligand","XP_016883799.1//PREDICTED: ICOS ligand isoform X4 [Homo sapiens];NP_001269980.1//ICOS ligand isoform c precursor [Homo sapiens];BAA31628.1//KIAA0653 protein, partial [Homo sapiens]","1//3;5"]
[8743,1943,0.11,0.41,1.89812038598079,0.0842476025913163,"*",0.0382632,"TNFSF10","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005576//extracellular region","GO:0005164//tumor necrosis factor receptor binding;GO:0005125//cytokine activity;GO:0042802//identical protein binding;GO:0008270//zinc ion binding;GO:0005102//receptor binding","GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007165//signal transduction;GO:0032868//response to insulin;GO:0097296//activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway;GO:0007267//cell-cell signaling;GO:0007166//cell surface receptor signaling pathway;GO:0008584//male gonad development;GO:0006915//apoptotic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:1902041//regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0043065//positive regulation of apoptotic process;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0006955//immune response;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors","K04721//tumor necrosis factor ligand superfamily member 10","NP_003801.1//tumor necrosis factor ligand superfamily member 10 isoform 1 [Homo sapiens];EAW78467.1//tumor necrosis factor (ligand) superfamily, member 10, isoform CRA_c, partial [Homo sapiens];NP_001177872.1//tumor necrosis factor ligand superfamily member 10 isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[445577,1154,0.2,0.74,1.88752527074159,0.052227096239718,"*",0.0222588,"C9orf129","GO:0005634//nucleus","NA","GO:0035357//peroxisome proliferator activated receptor signaling pathway;GO:0045444//fat cell differentiation","NA","NP_001092278.1//putative uncharacterized protein C9orf129 [Homo sapiens]","1//3"]
[3553,1498,0.16,0.59,1.88264304936184,0.0775109479314668,"*",0.0348348,"IL1B","GO:0070062//extracellular exosome;GO:0030141//secretory granule;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005576//extracellular region","GO:0019904//protein domain specific binding;GO:0005125//cytokine activity;GO:0005149//interleukin-1 receptor binding","GO:0071407//cellular response to organic cyclic compound;GO:0071260//cellular response to mechanical stimulus;GO:0035690//cellular response to drug;GO:0000187//activation of MAPK activity;GO:0007267//cell-cell signaling;GO:0006915//apoptotic process","K04519//interleukin 1 beta","EAW73607.1//interleukin 1, beta, isoform CRA_c [Homo sapiens]","2//1"]
[64090,1449,0.06,0.22,1.87446911791614,0.356248981981982,"*",0.217844,"GAL3ST2","GO:0016020//membrane;GO:0032580//Golgi cisterna membrane;GO:0016021//integral component of membrane","GO:0008146//sulfotransferase activity;GO:0001733//galactosylceramide sulfotransferase activity","GO:0009247//glycolipid biosynthetic process","K09675//galactose-3-O-sulfotransferase 2 [EC:2.8.2.-]","NP_071417.2//galactose-3-O-sulfotransferase 2 [Homo sapiens]","2//1"]
[1305,2816,0.03,0.11,1.87446911791614,0.356176054861822,"*",0.217844,"COL13A1","NA","NA","NA","K16617//collagen, type XIII, alpha","XP_005968572.1//PREDICTED: LOW QUALITY PROTEIN: collagen alpha-1(XIII) chain [Pantholops hodgsonii];XP_012618095.1//collagen alpha-1(XIII) chain isoform X7 [Microcebus murinus];XP_018891109.1//PREDICTED: collagen alpha-1(XIII) chain isoform X5 [Gorilla gorilla gorilla];XP_021799086.1//collagen alpha-1(XIII) chain isoform X2 [Papio anubis]","1//3;3//A2MP1"]
[7544,4989,0.03,0.11,1.87446911791614,0.20321941821161,"*",0.1086958,"ZFY","GO:0005654//nucleoplasm;GO:0005730//nucleolus","GO:0046872//metal ion binding;GO:0003677//DNA binding","GO:0006355//regulation of transcription, DNA-templated;GO:0007275//multicellular organism development;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","NP_003402.2//zinc finger Y-chromosomal protein isoform 1 [Homo sapiens];XP_011529777.1//PREDICTED: zinc finger Y-chromosomal protein isoform X3 [Homo sapiens];NP_001138748.1//zinc finger Y-chromosomal protein isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[3164,3040,31.54,115.21,1.8690113800485,0,"Up",0,"NR4A1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0005667//transcription factor complex;GO:0005829//cytosol","GO:0003707//steroid hormone receptor activity;GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity;GO:0035259//glucocorticoid receptor binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0042803//protein homodimerization activity;GO:0004879//nuclear receptor activity;GO:0043565//sequence-specific DNA binding;GO:0008270//zinc ion binding;GO:0008134//transcription factor binding","GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0071376//cellular response to corticotropin-releasing hormone stimulus;GO:0045786//negative regulation of cell cycle;GO:0035767//endothelial cell chemotaxis;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0061469//regulation of type B pancreatic cell proliferation;GO:0043065//positive regulation of apoptotic process;GO:0002042//cell migration involved in sprouting angiogenesis;GO:0001938//positive regulation of endothelial cell proliferation;GO:0007165//signal transduction;GO:0006351//transcription, DNA-templated;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0006915//apoptotic process;GO:0035914//skeletal muscle cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045444//fat cell differentiation;GO:0006367//transcription initiation from RNA polymerase II promoter","K04465//nuclear receptor subfamily 4 group A member 1","XP_016874736.1//PREDICTED: nuclear receptor subfamily 4 group A member 1 isoform X2 [Homo sapiens];NP_001189163.1//nuclear receptor subfamily 4 group A member 1 isoform 3 [Homo sapiens]","4;1//3;2//1"]
[3431,2112,2.01,7.31,1.86267590477351,{"v":4.52040766259169E-19,"d":"4.52E-19"},"Up",{"v":2.31482e-20,"d":"2.31E-20"},"SP110","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0004871//signal transducer activity","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0016032//viral process","K15413//nuclear autoantigen Sp-100","NP_004500.3//sp110 nuclear body protein isoform a [Homo sapiens];NP_001171944.1//sp110 nuclear body protein isoform d [Homo sapiens];NP_536349.2//sp110 nuclear body protein isoform c [Homo sapiens];NP_004501.3//sp110 nuclear body protein isoform b [Homo sapiens]","1//3;3//A2MP1;2//1"]
[4939,2807,0.08,0.29,1.85798099512757,0.255200835110132,"*",0.1450622,"OAS2","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005654//nucleoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm","GO:0046872//metal ion binding;GO:0005524//ATP binding;GO:0008270//zinc ion binding;GO:0001730//2'-5'-oligoadenylate synthetase activity;GO:0016740//transferase activity;GO:0003725//double-stranded RNA binding","GO:0006401//RNA catabolic process;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0060337//type I interferon signaling pathway;GO:0006486//protein glycosylation;GO:0051607//defense response to virus;GO:0006139//nucleobase-containing compound metabolic process;GO:0006955//immune response;GO:0006164//purine nucleotide biosynthetic process;GO:0009615//response to virus;GO:0018377//protein myristoylation","K14216//2'-5'-oligoadenylate synthetase [EC:2.7.7.84]","NP_001027903.1//2'-5'-oligoadenylate synthase 2 isoform 3 [Homo sapiens];NP_002526.2//2'-5'-oligoadenylate synthase 2 isoform 2 [Homo sapiens];EAW98026.1//2'-5'-oligoadenylate synthetase 2, 69/71kDa, isoform CRA_a [Homo sapiens]","1//3;2//1"]
[93659,880,0.62,2.23,1.84670358953343,0.00440111414154087,"*",1.405414E-3,"CGB5","GO:0005576//extracellular region","GO:0005179//hormone activity","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0016486//peptide hormone processing;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0007292//female gamete generation;GO:0006915//apoptotic process","K10045//chorionic gonadotropin, beta polypeptide","Q6NT52.4//RecName: Full=Choriogonadotropin subunit beta variant 2; Flags: Precursor","1//3"]
[9246,1285,24.63,88.46,1.84460861439969,{"v":1.021163052e-132,"d":"1.02E-132"},"Up",{"v":4.47486e-135,"d":"4.47E-135"},"UBE2L6","GO:0005654//nucleoplasm;GO:0005829//cytosol","GO:0043130//ubiquitin binding;GO:0005524//ATP binding;GO:0042296//ISG15 transferase activity;GO:0004842//ubiquitin-protein transferase activity","GO:0044267//cellular protein metabolic process;GO:0019985//translesion synthesis;GO:0032020//ISG15-protein conjugation;GO:0006464//cellular protein modification process;GO:0032480//negative regulation of type I interferon production;GO:0019941//modification-dependent protein catabolic process","K04553//ubiquitin-conjugating enzyme E2 L6 [EC:2.3.2.23]","EAW73755.1//ubiquitin-conjugating enzyme E2L 6, isoform CRA_a, partial [Homo sapiens];XP_017706859.1//PREDICTED: ubiquitin/ISG15-conjugating enzyme E2 L6 [Rhinopithecus bieti]","4;2//1"]
[57402,1075,0.15,0.53,1.82102985895468,0.203266999438071,"*",0.1086958,"S100A14","GO:0070062//extracellular exosome;GO:0016604//nuclear body;GO:0005829//cytosol;GO:0030054//cell junction;GO:0048471//perinuclear region of cytoplasm","GO:0005509//calcium ion binding;GO:0042379//chemokine receptor binding","GO:0071624//positive regulation of granulocyte chemotaxis;GO:0090026//positive regulation of monocyte chemotaxis;GO:0032496//response to lipopolysaccharide;GO:0042742//defense response to bacterium;GO:0055074//calcium ion homeostasis;GO:0034142//toll-like receptor 4 signaling pathway;GO:0006915//apoptotic process","NA","NP_065723.1//protein S100-A14 [Homo sapiens]","2//1"]
[4837,1579,46.38,163.67,1.8192151812141,{"v":7.57606885E-295,"d":"7.58E-295"},"Up",{"v":7.5884e-298,"d":"7.59E-298"},"NNMT","GO:0005829//cytosol","GO:0030760//pyridine N-methyltransferase activity;GO:0008112//nicotinamide N-methyltransferase activity","GO:0031100//animal organ regeneration;GO:0042493//response to drug;GO:0034356//NAD biosynthesis via nicotinamide riboside salvage pathway;GO:0010243//response to organonitrogen compound;GO:0032259//methylation","K00541//nicotinamide N-methyltransferase [EC:2.1.1.1]","NP_006160.1//nicotinamide N-methyltransferase [Homo sapiens]","2//1"]
[146325,2245,0.04,0.14,1.8073549220576,0.356358428673835,"*",0.217844,"PRR35","NA","NA","NA","K16628//collagen, type VII, alpha;K08582//calpain-15 [EC:3.4.22.-];K18808//toll-like receptor 13","NP_660313.1//proline-rich protein 35 [Homo sapiens]","2//1"]
[885,759,0.22,0.77,1.8073549220576,0.203195635950848,"*",0.1086958,"CCK","GO:0030425//dendrite;GO:0030424//axon;GO:0005615//extracellular space;GO:0043194//axon initial segment;GO:0043203//axon hillock;GO:0005576//extracellular region;GO:0043195//terminal bouton;GO:0043204//perikaryon","GO:0005184//neuropeptide hormone activity;GO:0005179//hormone activity","GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0007165//signal transduction;GO:0042755//eating behavior;GO:0014049//positive regulation of glutamate secretion;GO:0051901//positive regulation of mitochondrial depolarization;GO:0032099//negative regulation of appetite;GO:0001662//behavioral fear response;GO:0007409//axonogenesis;GO:0032461//positive regulation of protein oligomerization;GO:0001764//neuron migration;GO:0051930//regulation of sensory perception of pain;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0001836//release of cytochrome c from mitochondria;GO:0008284//positive regulation of cell proliferation","K05226//cholecystokinin","NP_000720.1//cholecystokinin preproprotein [Homo sapiens]","2//1;5"]
[5923,5382,0.02,0.07,1.8073549220576,0.356103157593123,"*",0.217844,"RASGRF1","GO:0030426//growth cone;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005886//plasma membrane;GO:0043005//neuron projection","GO:0035254//glutamate receptor binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005089//Rho guanyl-nucleotide exchange factor activity","GO:0034976//response to endoplasmic reticulum stress;GO:0035556//intracellular signal transduction;GO:0043547//positive regulation of GTPase activity;GO:0007616//long-term memory;GO:2000310//regulation of NMDA receptor activity;GO:0046578//regulation of Ras protein signal transduction;GO:0008283//cell proliferation;GO:0046579//positive regulation of Ras protein signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0048168//regulation of neuronal synaptic plasticity;GO:0031175//neuron projection development;GO:0090630//activation of GTPase activity;GO:0000165//MAPK cascade;GO:0007165//signal transduction;GO:0035020//regulation of Rac protein signal transduction;GO:0035023//regulation of Rho protein signal transduction;GO:0048167//regulation of synaptic plasticity","K04349//Ras-specific guanine nucleotide-releasing factor 1","NP_001139120.1//ras-specific guanine nucleotide-releasing factor 1 isoform 3 [Homo sapiens];AAA58417.1//CDC25 [Homo sapiens];NP_002882.3//ras-specific guanine nucleotide-releasing factor 1 isoform 1 [Homo sapiens]","1//3;4;2//1"]
[10568,4164,0.02,0.07,1.8073549220576,0.53046565920398,"*",0.37379,"SLC34A2","GO:0005903//brush border;GO:0016324//apical plasma membrane;GO:0031526//brush border membrane;GO:0031982//vesicle;GO:0005737//cytoplasm;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0042301//phosphate ion binding;GO:0005436//sodium:phosphate symporter activity;GO:0031402//sodium ion binding;GO:0015321//sodium-dependent phosphate transmembrane transporter activity","GO:0044267//cellular protein metabolic process;GO:0006817//phosphate ion transport;GO:0030643//cellular phosphate ion homeostasis;GO:0001701//in utero embryonic development;GO:0043627//response to estrogen","K14683//solute carrier family 34 (sodium-dependent phosphate cotransporter)","NP_001171469.1//sodium-dependent phosphate transport protein 2B isoform b [Homo sapiens];NP_006415.2//sodium-dependent phosphate transport protein 2B isoform a [Homo sapiens]","1//3;2//1"]
[4776,4630,0.02,0.07,1.8073549220576,0.356030290157561,"*",0.217844,"NFATC4","GO:0005634//nucleus;GO:0005667//transcription factor complex;GO:0005829//cytosol;GO:0016607//nuclear speck","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003713//transcription coactivator activity;GO:0008134//transcription factor binding;GO:0001227//transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0042975//peroxisome proliferator activated receptor binding","GO:0055001//muscle cell development;GO:0030178//negative regulation of Wnt signaling pathway;GO:0034644//cellular response to UV;GO:0032760//positive regulation of tumor necrosis factor production;GO:0032091//negative regulation of protein binding;GO:0033173//calcineurin-NFAT signaling cascade;GO:0045333//cellular respiration;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0007507//heart development;GO:0050774//negative regulation of dendrite morphogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0051145//smooth muscle cell differentiation;GO:0006954//inflammatory response;GO:2001235//positive regulation of apoptotic signaling pathway;GO:1904637//cellular response to ionomycin;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:2000297//negative regulation of synapse maturation;GO:0035562//negative regulation of chromatin binding;GO:0001569//branching involved in blood vessel morphogenesis;GO:1902894//negative regulation of pri-miRNA transcription from RNA polymerase II promoter;GO:0071285//cellular response to lithium ion;GO:0048167//regulation of synaptic plasticity","K17334//nuclear factor of activated T-cells, cytoplasmic 4","NP_004545.2//nuclear factor of activated T-cells, cytoplasmic 4 isoform 2 [Homo sapiens];NP_001185896.1//nuclear factor of activated T-cells, cytoplasmic 4 isoform 5 [Homo sapiens];NP_001275731.1//nuclear factor of activated T-cells, cytoplasmic 4 isoform 6 [Homo sapiens];NP_001129494.1//nuclear factor of activated T-cells, cytoplasmic 4 isoform 1 [Homo sapiens];NP_001306972.1//nuclear factor of activated T-cells, cytoplasmic 4 isoform 7 [Homo sapiens]","1//3;4;2//1"]
[9379,6149,0.02,0.07,1.8073549220576,0.530041851753218,"*",0.37379,"NRXN2","GO:0043234//protein complex;GO:0098793//presynapse;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0097109//neuroligin family protein binding;GO:0046872//metal ion binding;GO:0050839//cell adhesion molecule binding;GO:0004888//transmembrane signaling receptor activity;GO:0005246//calcium channel regulator activity","GO:0097116//gephyrin clustering involved in postsynaptic density assembly;GO:0035176//social behavior;GO:0007165//signal transduction;GO:0097104//postsynaptic membrane assembly;GO:0007416//synapse assembly;GO:0042297//vocal learning;GO:0007269//neurotransmitter secretion;GO:0097118//neuroligin clustering involved in postsynaptic membrane assembly;GO:0030534//adult behavior;GO:0007268//chemical synaptic transmission;GO:0071625//vocalization behavior;GO:0007158//neuron cell-cell adhesion;GO:0097119//postsynaptic density protein 95 clustering","K07377//neurexin","XP_004394041.1//PREDICTED: neurexin-2-beta isoform X1 [Odobenus rosmarus divergens];NP_620060.1//neurexin-2-beta isoform alpha-2 precursor [Homo sapiens];NP_620063.1//neurexin-2-beta isoform beta precursor [Homo sapiens]","3//A2MP1;2//1"]
[56122,3973,0.02,0.07,1.8073549220576,0.52966570212011,"*",0.37379,"PCDHB14","GO:0005887//integral component of plasma membrane","GO:0005509//calcium ion binding","GO:0007416//synapse assembly;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007268//chemical synaptic transmission","K16494//protocadherin beta","XP_002816041.3//PREDICTED: uncharacterized protein LOC100450339 [Pongo abelii]","3//A2MP1"]
[390205,2230,0.04,0.14,1.8073549220576,0.355775488804826,"*",0.217844,"LRRC10B","NA","NA","NA","K16175//protein scribble;K17277//epidermal growth factor receptor kinase substrate 8","NP_001138549.1//leucine-rich repeat-containing protein 10B [Homo sapiens]","1//3"]
[4973,2440,0.2,0.7,1.8073549220576,0.0105184680100756,"*",0.0036598,"OLR1","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0005654//nucleoplasm;GO:0043235//receptor complex;GO:0005887//integral component of plasma membrane;GO:0045121//membrane raft;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane;GO:0005886//plasma membrane;GO:0070821//tertiary granule membrane","GO:0005041//low-density lipoprotein receptor activity;GO:0030246//carbohydrate binding;GO:0042802//identical protein binding","GO:0008015//blood circulation;GO:0007155//cell adhesion;GO:0006508//proteolysis;GO:0050900//leukocyte migration;GO:0043312//neutrophil degranulation;GO:0006954//inflammatory response","K08763//oxidised low-density lipoprotein receptor 1","NP_001166103.1//oxidized low-density lipoprotein receptor 1 isoform 2 [Homo sapiens];NP_001166104.1//oxidized low-density lipoprotein receptor 1 isoform 3 [Homo sapiens];NP_002534.1//oxidized low-density lipoprotein receptor 1 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[85441,8889,1.98,6.81,1.78215436793246,{"v":6.04282407719298e-61,"d":"6.04E-61"},"Up",{"v":6.46878e-63,"d":"6.47E-63"},"HELZ2","GO:0016020//membrane;GO:0005654//nucleoplasm","GO:0003723//RNA binding;GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0005524//ATP binding;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0004386//helicase activity","GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0019216//regulation of lipid metabolic process;GO:0006351//transcription, DNA-templated","K16628//collagen, type VII, alpha","NP_208384.3//helicase with zinc finger domain 2 isoform 2 [Homo sapiens];XP_017736734.1//PREDICTED: helicase with zinc finger domain 2 isoform X2 [Rhinopithecus bieti]","3//A2MP1;2//1"]
[639,5017,0.68,2.33,1.77672330340394,{"v":5.66852571900827e-14,"d":"5.67E-14"},"Up",{"v":4.2938e-15,"d":"4.29E-15"},"PRDM1","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0042826//histone deacetylase binding;GO:1990841//promoter-specific chromatin binding;GO:0003676//nucleic acid binding;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:1990654//sebum secreting cell proliferation;GO:0031665//negative regulation of lipopolysaccharide-mediated signaling pathway;GO:0032823//regulation of natural killer cell differentiation;GO:0001763//morphogenesis of a branching structure;GO:0009791//post-embryonic development;GO:0003170//heart valve development;GO:0035904//aorta development;GO:0060576//intestinal epithelial cell development;GO:0003281//ventricular septum development;GO:0001893//maternal placenta development;GO:0060976//coronary vasculature development;GO:0051136//regulation of NK T cell differentiation;GO:0045165//cell fate commitment;GO:0033082//regulation of extrathymic T cell differentiation;GO:0045579//positive regulation of B cell differentiation;GO:0010628//positive regulation of gene expression;GO:0060707//trophoblast giant cell differentiation;GO:0007281//germ cell development;GO:0048844//artery morphogenesis;GO:0030889//negative regulation of B cell proliferation;GO:0042462//eye photoreceptor cell development","K09228//KRAB domain-containing zinc finger protein","XP_012293896.1//PR domain zinc finger protein 1 isoform X1 [Aotus nancymaae];XP_017399256.1//PREDICTED: PR domain zinc finger protein 1 isoform X3 [Cebus capucinus imitator]","3//A2MP1;2//1"]
[151636,5768,5.86,20.05,1.77462966692003,{"v":8.86296016338028e-131,"d":"8.86E-131"},"Up",{"v":3.93934e-133,"d":"3.94E-133"},"DTX3L","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0043234//protein complex;GO:0005829//cytosol;GO:0005764//lysosome;GO:0005737//cytoplasm","GO:0042393//histone binding;GO:0003723//RNA binding;GO:0097677//STAT family protein binding;GO:0004842//ubiquitin-protein transferase activity;GO:0046872//metal ion binding;GO:0004857//enzyme inhibitor activity;GO:0044389//ubiquitin-like protein ligase binding;GO:0008047//enzyme activator activity;GO:0019899//enzyme binding","GO:0070936//protein K48-linked ubiquitination;GO:0051444//negative regulation of ubiquitin-protein transferase activity;GO:0010390//histone monoubiquitination;GO:1902966//positive regulation of protein localization to early endosome;GO:1901666//positive regulation of NAD+ ADP-ribosyltransferase activity;GO:0035563//positive regulation of chromatin binding;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:2000646//positive regulation of receptor catabolic process;GO:2001034//positive regulation of double-strand break repair via nonhomologous end joining;GO:0045893//positive regulation of transcription, DNA-templated;GO:0032092//positive regulation of protein binding;GO:0006302//double-strand break repair;GO:0051865//protein autoubiquitination;GO:0008333//endosome to lysosome transport;GO:0006974//cellular response to DNA damage stimulus;GO:0000209//protein polyubiquitination;GO:1900182//positive regulation of protein localization to nucleus;GO:0033522//histone H2A ubiquitination;GO:0033523//histone H2B ubiquitination;GO:0002230//positive regulation of defense response to virus by host","K06058//deltex [EC:2.3.2.27]","NP_612144.1//E3 ubiquitin-protein ligase DTX3L [Homo sapiens]","3//A2MP1"]
[2243,2283,1.4,4.77,1.76856243906054,{"v":1.35023908545994E-12,"d":"1.35E-12"},"Up",{"v":1.139428e-13,"d":"1.14E-13"},"FGA","GO:0070062//extracellular exosome;GO:0005788//endoplasmic reticulum lumen;GO:0005577//fibrinogen complex;GO:0005615//extracellular space;GO:0072562//blood microparticle;GO:0009897//external side of plasma membrane;GO:0005938//cell cortex;GO:1903561//extracellular vesicle;GO:0031093//platelet alpha granule lumen;GO:0009986//cell surface;GO:0031091//platelet alpha granule;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0050839//cell adhesion molecule binding;GO:0046872//metal ion binding;GO:0030674//protein binding, bridging;GO:0005198//structural molecule activity;GO:0005102//receptor binding","GO:0043687//post-translational protein modification;GO:0007596//blood coagulation;GO:0030168//platelet activation;GO:0045921//positive regulation of exocytosis;GO:0072377//blood coagulation, common pathway;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:0044267//cellular protein metabolic process;GO:0002576//platelet degranulation;GO:0045907//positive regulation of vasoconstriction;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0043152//induction of bacterial agglutination;GO:0072378//blood coagulation, fibrin clot formation;GO:0090277//positive regulation of peptide hormone secretion;GO:0045087//innate immune response;GO:0034116//positive regulation of heterotypic cell-cell adhesion;GO:0042730//fibrinolysis;GO:0007165//signal transduction;GO:2000261//negative regulation of blood coagulation, common pathway;GO:0002224//toll-like receptor signaling pathway;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:0002250//adaptive immune response;GO:0031639//plasminogen activation;GO:0051258//protein polymerization;GO:0050714//positive regulation of protein secretion;GO:0007160//cell-matrix adhesion;GO:0051592//response to calcium ion;GO:0030198//extracellular matrix organization;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0006461//protein complex assembly;GO:0070527//platelet aggregation;GO:0043623//cellular protein complex assembly","K03903//fibrinogen alpha chain","NP_068657.1//fibrinogen alpha chain isoform alpha precursor [Homo sapiens];NP_000499.1//fibrinogen alpha chain isoform alpha-E preproprotein [Homo sapiens]","4;3//A2MP1"]
[5696,1390,6.64,22.62,1.7683437826429,{"v":1.7715166e-34,"d":"1.77E-34"},"Up",{"v":3.9924e-36,"d":"3.99E-36"},"PSMB8","NA","NA","NA","K02740//20S proteasome subunit beta 8 [EC:3.4.25.1]","XP_011727341.1//PREDICTED: proteasome subunit beta type-8 isoform X2 [Macaca nemestrina];XP_008992471.1//PREDICTED: LOW QUALITY PROTEIN: proteasome subunit beta type-8 [Callithrix jacchus]","4;3//A2MP1"]
[8858,1489,0.16,0.54,1.75488750216347,0.118413622146952,"*",0.0569014,"PROZ","GO:0070062//extracellular exosome;GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0005796//Golgi lumen","GO:0004252//serine-type endopeptidase activity;GO:0005509//calcium ion binding","GO:0030195//negative regulation of blood coagulation;GO:0007596//blood coagulation;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0006465//signal peptide processing;GO:0017187//peptidyl-glutamic acid carboxylation","K01314//coagulation factor X [EC:3.4.21.6]","NP_003882.1//vitamin K-dependent protein Z isoform 2 precursor [Homo sapiens];XP_016876301.1//PREDICTED: vitamin K-dependent protein Z isoform X1 [Homo sapiens]","1//3;2//1"]
[100288485,1494,0.16,0.54,1.75488750216347,0.118398197681386,"*",0.0569014,"MTRNR2L7","NA","NA","NA","NA","NA","1//3"]
[64816,1404,0.11,0.37,1.75002174699165,0.140025042669008,"*",0.0698898,"CYP3A43","GO:0031090//organelle membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0020037//heme binding;GO:0005506//iron ion binding;GO:0070330//aromatase activity;GO:0004497//monooxygenase activity;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen","NA","K17689//cytochrome P450 family 3 subfamily A polypeptide 4 [EC:1.14.13.32 1.14.13.67 1.14.13.97 1.14.13.157 1.14.13.-];K07424//cytochrome P450 family 3 subfamily A [EC:1.14.14.1];K17690//cytochrome P450 family 3 subfamily A polypeptide 5 [EC:1.14.14.1];K17692//cytochrome P450 family 3 subfamily A polypeptide 43 [EC:1.14.14.1]","NP_001265850.1//cytochrome P450 3A43 isoform 4 [Homo sapiens];CAD91343.1//cytochrome P450 [Homo sapiens];EHH52028.1//hypothetical protein EGM_12392 [Macaca fascicularis];XP_011799240.1//PREDICTED: cytochrome P450 3A43 isoform X3 [Colobus angolensis palliatus]","1//3;4;3//A2MP1;2//1"]
[27035,2382,0.03,0.1,1.73696559416621,0.531457183800623,"*",0.37379,"NOX1","GO:0071438//invadopodium membrane;GO:0043020//NADPH oxidase complex;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0005886//plasma membrane;GO:0005769//early endosome","GO:0050661//NADP binding;GO:0046872//metal ion binding;GO:0048365//Rac GTPase binding;GO:0030171//voltage-gated proton channel activity;GO:0016175//superoxide-generating NADPH oxidase activity","GO:0006801//superoxide metabolic process;GO:0008217//regulation of blood pressure;GO:0046330//positive regulation of JNK cascade;GO:0051454//intracellular pH elevation;GO:0006739//NADP metabolic process;GO:0016477//cell migration;GO:0010575//positive regulation of vascular endothelial growth factor production;GO:0055114//oxidation-reduction process;GO:1990451//cellular stress response to acidic pH;GO:0045726//positive regulation of integrin biosynthetic process;GO:1902177//positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:0042554//superoxide anion generation;GO:0015992//proton transport;GO:0007165//signal transduction;GO:0001525//angiogenesis;GO:0042743//hydrogen peroxide metabolic process;GO:0045730//respiratory burst;GO:0006954//inflammatory response;GO:0072592//oxygen metabolic process;GO:0030198//extracellular matrix organization;GO:0071455//cellular response to hyperoxia;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0003081//regulation of systemic arterial blood pressure by renin-angiotensin;GO:0008284//positive regulation of cell proliferation","K08008//NADPH oxidase 1","XP_010378484.1//PREDICTED: NADPH oxidase 1 isoform X1 [Rhinopithecus roxellana];XP_010378486.1//PREDICTED: NADPH oxidase 1 isoform X3 [Rhinopithecus roxellana];XP_010378485.1//PREDICTED: NADPH oxidase 1 isoform X2 [Rhinopithecus roxellana]","4;1//3;2//1"]
[254268,3063,0.03,0.1,1.73696559416621,0.356212514689323,"*",0.217844,"AKNAD1","NA","NA","NA","K21404//AT-hook-containing transcription factor","NP_689976.2//protein AKNAD1 [Homo sapiens]",4]
[6402,2442,0.03,0.1,1.73696559416621,0.53055993069131,"*",0.37379,"SELL","GO:0030667//secretory granule membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0002020//protease binding;GO:0050839//cell adhesion molecule binding;GO:0030246//carbohydrate binding;GO:0008201//heparin binding;GO:0043208//glycosphingolipid binding","GO:0033198//response to ATP;GO:0007155//cell adhesion;GO:0050900//leukocyte migration;GO:0043312//neutrophil degranulation;GO:0050776//regulation of immune response","K06495//selectin, lymphocyte","NP_000646.2//L-selectin precursor [Homo sapiens]",4]
[340393,1145,0.36,1.2,1.73696559416621,0.0452560753896882,"*",0.0189025,"TMEM249","GO:0016021//integral component of membrane","NA","NA","K10272//F-box and leucine-rich repeat protein 6","NP_001239331.1//transmembrane protein 249 isoform 1 [Homo sapiens];XP_008000253.1//PREDICTED: LOW QUALITY PROTEIN: transmembrane protein 249 [Chlorocebus sabaeus];NP_001239333.1//transmembrane protein 249 isoform 2 [Homo sapiens]","1//3;2//1"]
[27065,2418,0.03,0.1,1.73696559416621,0.530088908025568,"*",0.37379,"NSG1","GO:0030425//dendrite;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005770//late endosome;GO:0005737//cytoplasm;GO:0000139//Golgi membrane;GO:0005768//endosome;GO:0032588//trans-Golgi network membrane;GO:0098845//postsynaptic endosome;GO:0016021//integral component of membrane;GO:0016328//lateral plasma membrane;GO:0055037//recycling endosome;GO:0005769//early endosome;GO:0045211//postsynaptic membrane","GO:0005102//receptor binding;GO:0032051//clathrin light chain binding","GO:0099627//neurotransmitter receptor cycle;GO:0001881//receptor recycling;GO:0016197//endosomal transport;GO:0098814//spontaneous synaptic transmission;GO:1900271//regulation of long-term synaptic potentiation;GO:0001921//positive regulation of receptor recycling;GO:0007212//dopamine receptor signaling pathway;GO:0006915//apoptotic process;GO:0042982//amyloid precursor protein metabolic process;GO:0048268//clathrin coat assembly;GO:0099630//postsynaptic neurotransmitter receptor cycle;GO:0098887//neurotransmitter receptor transport, endosome to postsynaptic membrane","K10955//mucin-2;K15493//neuron-specific vesicular protein calcyon;K19582//lipid phosphate phosphatase-related protein type 3/4","EAW82430.1//DNA segment on chromosome 4 (unique) 234 expressed sequence, isoform CRA_a [Homo sapiens]","4;1//3"]
[134121,2460,0.03,0.1,1.73696559416621,0.529806695652174,"*",0.37379,"C5orf49","NA","NA","NA","K09291//nucleoprotein TPR","XP_003899537.1//uncharacterized protein C5orf49 homolog [Papio anubis]","2//1"]
[50619,2320,0.03,0.1,1.73696559416621,0.529712691625266,"*",0.37379,"DEF6","GO:0016020//membrane;GO:0005856//cytoskeleton;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0048471//perinuclear region of cytoplasm;GO:0030175//filopodium","NA","NA","K20072//switch-associated protein 70","XP_005553287.1//PREDICTED: differentially expressed in FDCP 6 homolog isoform X1 [Macaca fascicularis]","3//A2MP1"]
[391104,1014,0.16,0.53,1.7279204545632,0.303866758067263,"*",0.1787362,"VHLL","GO:0005929//cilium;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031462//Cul2-RING ubiquitin ligase complex;GO:0005730//nucleolus;GO:0030891//VCB complex","GO:0061630//ubiquitin protein ligase activity;GO:0032403//protein complex binding","GO:0006607//NLS-bearing protein import into nucleus;GO:0006582//melanin metabolic process;GO:0016567//protein ubiquitination;GO:0010629//negative regulation of gene expression;GO:0043534//blood vessel endothelial cell migration;GO:0003309//type B pancreatic cell differentiation;GO:0061073//ciliary body morphogenesis;GO:0010498//proteasomal protein catabolic process;GO:0045602//negative regulation of endothelial cell differentiation;GO:2001233//regulation of apoptotic signaling pathway;GO:0001525//angiogenesis;GO:0003310//pancreatic A cell differentiation;GO:1902072//negative regulation of hypoxia-inducible factor-1alpha signaling pathway;GO:0048877//homeostasis of number of retina cells;GO:0048069//eye pigmentation;GO:0061072//iris morphogenesis;GO:0030198//extracellular matrix organization;GO:0070244//negative regulation of thymocyte apoptotic process;GO:1903827//regulation of cellular protein localization;GO:0050679//positive regulation of epithelial cell proliferation","K03871//von Hippel-Lindau disease tumor supressor","NP_001004319.1//von Hippel-Lindau-like protein [Homo sapiens]","2//1"]
[10346,3099,0.1,0.33,1.72246602447109,0.0692726367428004,"*",0.0305686,"TRIM22","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0015030//Cajal body;GO:0005737//cytoplasm","GO:0003714//transcription corepressor activity;GO:0030674//protein binding, bridging;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0003700//DNA binding transcription factor activity;GO:0019901//protein kinase binding","GO:0060333//interferon-gamma-mediated signaling pathway;GO:0006355//regulation of transcription, DNA-templated;GO:0070206//protein trimerization;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0016567//protein ubiquitination;GO:0051607//defense response to virus;GO:0006351//transcription, DNA-templated;GO:0016032//viral process;GO:0010508//positive regulation of autophagy;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0032880//regulation of protein localization;GO:0006955//immune response;GO:0009615//response to virus","K11999//tripartite motif-containing protein 6/22/34","NP_001186502.1//E3 ubiquitin-protein ligase TRIM22 isoform 2 [Homo sapiens];NP_006065.2//E3 ubiquitin-protein ligase TRIM22 isoform 1 [Homo sapiens]","1//3;4"]
[6004,2432,0.07,0.23,1.71620703399941,0.203171859255792,"*",0.1086958,"RGS16","GO:0031224//intrinsic component of membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0005516//calmodulin binding;GO:0005096//GTPase activator activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0009968//negative regulation of signal transduction;GO:0007601//visual perception;GO:0043547//positive regulation of GTPase activity","K16449//regulator of G-protein signaling","NP_002919.3//regulator of G-protein signaling 16 [Homo sapiens]","3//A2MP1"]
[9021,2737,23.63,76.88,1.7019887067999,{"v":1.10460337792E-221,"d":"1.10E-221"},"Up",{"v":1.728752E-224,"d":"1.73E-224"},"SOCS3","GO:0005829//cytosol;GO:0005622//intracellular;GO:0005737//cytoplasm","GO:0004860//protein kinase inhibitor activity;GO:0001784//phosphotyrosine residue binding","GO:0043687//post-translational protein modification;GO:0007259//JAK-STAT cascade;GO:0040008//regulation of growth;GO:0016567//protein ubiquitination;GO:0060708//spongiotrophoblast differentiation;GO:0050728//negative regulation of inflammatory response;GO:0042532//negative regulation of tyrosine phosphorylation of STAT protein;GO:0001932//regulation of protein phosphorylation;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0060334//regulation of interferon-gamma-mediated signaling pathway;GO:0045597//positive regulation of cell differentiation;GO:0060674//placenta blood vessel development;GO:0046426//negative regulation of JAK-STAT cascade;GO:0043066//negative regulation of apoptotic process;GO:0060707//trophoblast giant cell differentiation;GO:0006469//negative regulation of protein kinase activity;GO:1990830//cellular response to leukemia inhibitory factor;GO:0060670//branching involved in labyrinthine layer morphogenesis;GO:0019221//cytokine-mediated signaling pathway","K04696//suppressor of cytokine signaling 3","OWK15009.1//SOCS3 [Cervus elaphus hippelaphus]",4]
[339145,1921,0.04,0.13,1.70043971814109,0.531315310553479,"*",0.37379,"FAM92B","GO:0005814//centriole;GO:0042995//cell projection","NA","GO:0030030//cell projection organization","K15421//secretion-regulating guanine nucleotide exchange factor;K02258//cytochrome c oxidase assembly protein subunit 11;K10837//O-phosphoseryl-tRNA(Sec) kinase [EC:2.7.1.164]","NP_940893.1//protein FAM92B [Homo sapiens]","2//1"]
[219285,6541,0.24,0.78,1.70043971814109,{"v":1.69130987600292E-6,"d":"1.69E-06"},"Up",{"v":2.9032e-07,"d":"2.90E-07"},"SAMD9L","GO:0005769//early endosome","NA","GO:0034058//endosomal vesicle fusion","NA","NP_689916.2//sterile alpha motif domain-containing protein 9-like [Homo sapiens]","4;1//3;2//1"]
[1470,694,0.12,0.39,1.70043971814109,0.530984567363273,"*",0.37379,"CST2","GO:0005615//extracellular space","GO:0002020//protease binding;GO:0004869//cysteine-type endopeptidase inhibitor activity","GO:2000117//negative regulation of cysteine-type endopeptidase activity;GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste","K13898//cystatin-SA","NP_001313.1//cystatin-SA precursor [Homo sapiens]","2//1"]
[6861,1823,0.27,0.87,1.68805599368526,0.0159973565265145,"*",0.00583552,"SYT5","GO:1990769//proximal neuron projection;GO:0030054//cell junction;GO:0048471//perinuclear region of cytoplasm;GO:0043025//neuronal cell body;GO:0055038//recycling endosome membrane;GO:0030672//synaptic vesicle membrane;GO:0031045//dense core granule;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005544//calcium-dependent phospholipid binding;GO:0030276//clathrin binding;GO:0005509//calcium ion binding;GO:0046982//protein heterodimerization activity;GO:0019905//syntaxin binding;GO:0001786//phosphatidylserine binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding","GO:0006906//vesicle fusion;GO:0048488//synaptic vesicle endocytosis;GO:0048791//calcium ion-regulated exocytosis of neurotransmitter;GO:0007268//chemical synaptic transmission;GO:0017158//regulation of calcium ion-dependent exocytosis","K19905//synaptotagmin-5","NP_003171.2//synaptotagmin-5 isoform 1 [Homo sapiens];XP_018871641.1//PREDICTED: synaptotagmin-5 isoform X3 [Gorilla gorilla gorilla]","1//3;2//1"]
[6543,5111,0.09,0.29,1.68805599368526,0.0239994062941847,"*",0.00922326,"SLC8A2","GO:0016323//basolateral plasma membrane;GO:0005887//integral component of plasma membrane;GO:0043197//dendritic spine;GO:0005886//plasma membrane;GO:0043204//perikaryon","GO:0046872//metal ion binding;GO:0005432//calcium:sodium antiporter activity;GO:0005516//calmodulin binding","GO:1903779//regulation of cardiac conduction;GO:0070588//calcium ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0007154//cell communication;GO:0007612//learning;GO:0006811//ion transport;GO:0007613//memory;GO:0060291//long-term synaptic potentiation;GO:0048172//regulation of short-term neuronal synaptic plasticity;GO:0006874//cellular calcium ion homeostasis","K05849//solute carrier family 8 (sodium/calcium exchanger)","XP_007995551.1//PREDICTED: sodium/calcium exchanger 2 isoform X1 [Chlorocebus sabaeus]","2//1"]
[1052,1269,24.11,77.66,1.68754005630595,{"v":1.02300214978723E-100,"d":"1.02E-100"},"Up",{"v":6.01992e-103,"d":"6.02E-103"},"CEBPD","GO:0005654//nucleoplasm","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0046982//protein heterodimerization activity;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0042803//protein homodimerization activity","GO:0045892//negative regulation of transcription, DNA-templated;GO:0002244//hematopoietic progenitor cell differentiation;GO:0045444//fat cell differentiation;GO:0048839//inner ear development;GO:0045669//positive regulation of osteoblast differentiation;GO:0006366//transcription from RNA polymerase II promoter","K10050//CCAAT/enhancer binding protein (C/EBP), delta","NP_005186.2//CCAAT/enhancer-binding protein delta [Homo sapiens]","3//A2MP1"]
[374897,1153,0.56,1.8,1.68449817427207,0.012579335201549,"*",0.00447372,"SBSN","GO:0031012//extracellular matrix;GO:0070062//extracellular exosome","NA","NA","K18626//trichohyalin","NP_001159506.1//suprabasin isoform 1 precursor [Homo sapiens];NP_001159507.1//suprabasin isoform 3 precursor [Homo sapiens];NP_940940.1//suprabasin isoform 2 precursor [Homo sapiens]","1//3;3//A2MP1"]
[10335,6280,0.05,0.16,1.67807190511264,0.0497644811954431,"*",0.0210566,"MRVI1","GO:0031095//platelet dense tubular network membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0016529//sarcoplasmic reticulum;GO:0048471//perinuclear region of cytoplasm","NA","NA","K12337//inositol 1,4,5-triphosphate receptor-associated cGMP kinase substrate","NP_569056.4//protein MRVI1 isoform d [Homo sapiens];BAH13268.1//unnamed protein product [Homo sapiens];NP_001193809.1//protein MRVI1 isoform e [Homo sapiens];NP_001092049.2//protein MRVI1 isoform a [Homo sapiens]","1//3;3//A2MP1;2//1"]
[401551,1275,0.06,0.19,1.66296501272243,0.52961872095086,"*",0.37379,"WDR38","NA","NA","NA","K19760//dynein assembly factor with WDR repeat domains 1;K18643//katanin p80 WD40 repeat-containing subunit B1;K16482//centriolar protein POC1","NP_001263305.1//WD repeat-containing protein 38 isoform 4 [Homo sapiens];XP_003918857.2//WD repeat-containing protein 38 isoform X4 [Papio anubis]","1//3;2//1"]
[51339,3766,0.12,0.38,1.66296501272243,0.0356518940958269,"*",0.0144402,"DACT1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0030877//beta-catenin destruction complex;GO:0030054//cell junction;GO:0045202//synapse;GO:0005737//cytoplasm","GO:0005080//protein kinase C binding;GO:0051018//protein kinase A binding;GO:0042826//histone deacetylase binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0070097//delta-catenin binding;GO:0008013//beta-catenin binding","GO:2000095//regulation of Wnt signaling pathway, planar cell polarity pathway;GO:0030178//negative regulation of Wnt signaling pathway;GO:0032092//positive regulation of protein binding;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0046329//negative regulation of JNK cascade;GO:0032091//negative regulation of protein binding;GO:0021915//neural tube development;GO:1903364//positive regulation of cellular protein catabolic process;GO:0035412//regulation of catenin import into nucleus;GO:0035413//positive regulation of catenin import into nucleus;GO:1904864//negative regulation of beta-catenin-TCF complex assembly;GO:0048619//embryonic hindgut morphogenesis;GO:0030177//positive regulation of Wnt signaling pathway;GO:0045732//positive regulation of protein catabolic process;GO:0031647//regulation of protein stability;GO:0016055//Wnt signaling pathway","K22154//dapper","XP_007985007.1//PREDICTED: dapper homolog 1 isoform X1 [Chlorocebus sabaeus];XP_007985008.1//PREDICTED: dapper homolog 1 isoform X2 [Chlorocebus sabaeus]","1//3;5"]
[924,1318,0.06,0.19,1.66296501272243,0.529243171423507,"*",0.37379,"CD7","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004872//receptor activity","GO:0042110//T cell activation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0006955//immune response;GO:0048873//homeostasis of number of cells within a tissue;GO:0002250//adaptive immune response","K06457//T-cell surface glycoprotein CD7","NP_006128.1//T-cell antigen CD7 precursor [Homo sapiens]",6]
[23034,6652,1.69,5.35,1.66251564500632,{"v":7.82957215255255e-37,"d":"7.83E-37"},"Up",{"v":1.632182e-38,"d":"1.63E-38"},"SAMD4A","GO:0030425//dendrite;GO:0005829//cytosol;GO:0001650//fibrillar center;GO:0030054//cell junction;GO:0045202//synapse;GO:0000932//P-body","GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0030371//translation repressor activity","GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0043488//regulation of mRNA stability;GO:0045727//positive regulation of translation","NA","NP_056404.4//protein Smaug homolog 1 isoform 1 [Homo sapiens];NP_001155048.2//protein Smaug homolog 1 isoform 2 [Homo sapiens];AAH21726.2//SAMD4A protein, partial [Homo sapiens]","1//3;2//1;5"]
[79713,1659,8.11,25.53,1.65441971818985,{"v":7.8405190051282e-43,"d":"7.84E-43"},"Up",{"v":1.339966e-44,"d":"1.34E-44"},"IGFLR1","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","NA","NA","NA","NP_078936.1//IGF-like family receptor 1 isoform a precursor [Homo sapiens];NP_001332935.1//IGF-like family receptor 1 isoform d precursor [Homo sapiens];XP_009230730.1//PREDICTED: IGF-like family receptor 1 isoform X1 [Pongo abelii];NP_001332932.1//IGF-like family receptor 1 isoform b precursor [Homo sapiens]","1//3;3//A2MP1"]
[3430,1255,19.74,62.11,1.65370357799031,{"v":1.10617668e-77,"d":"1.11E-77"},"Up",{"v":8.72532e-80,"d":"8.73E-80"},"IFI35","GO:0005634//nucleus;GO:0005829//cytosol","NA","GO:0060337//type I interferon signaling pathway","NA","NP_001317159.1//interferon-induced 35 kDa protein isoform 2 [Homo sapiens];NP_005524.2//interferon-induced 35 kDa protein isoform 1 [Homo sapiens]","1//3;4"]
[79025,1134,0.07,0.22,1.65207669657969,0.530654235691433,"*",0.37379,"FNDC11","GO:0070062//extracellular exosome","NA","NA","K19720//collagen, type III, alpha","XP_008960524.1//PREDICTED: uncharacterized protein C20orf195 homolog isoform X1 [Pan paniscus];XP_017736728.1//PREDICTED: uncharacterized protein C20orf195 homolog isoform X1 [Rhinopithecus bieti];XP_016883549.1//PREDICTED: uncharacterized protein C20orf195 isoform X1 [Homo sapiens]","1//3;3//A2MP1"]
[6795,1120,0.07,0.22,1.65207669657969,0.530135972653822,"*",0.37379,"AURKC","GO:0000793//condensed chromosome;GO:0051233//spindle midzone;GO:0000780//condensed nuclear chromosome, centromeric region;GO:0005737//cytoplasm;GO:0032133//chromosome passenger complex;GO:0030496//midbody;GO:0005819//spindle;GO:0031616//spindle pole centrosome;GO:0005876//spindle microtubule","GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0035174//histone serine kinase activity","GO:0032467//positive regulation of cytokinesis;GO:0048599//oocyte development;GO:0006468//protein phosphorylation;GO:0000910//cytokinesis;GO:0007283//spermatogenesis;GO:0051256//mitotic spindle midzone assembly;GO:0016570//histone modification;GO:0008608//attachment of spindle microtubules to kinetochore;GO:0051321//meiotic cell cycle;GO:0051255//spindle midzone assembly","K11480//aurora kinase C [EC:2.7.11.1]","XP_012355738.1//PREDICTED: aurora kinase C isoform X1 [Nomascus leucogenys];XP_005590555.1//PREDICTED: aurora kinase C [Macaca fascicularis];NP_001015879.1//aurora kinase C isoform 2 [Homo sapiens]","1//3;2//1"]
[2920,1234,15.52,48.53,1.64474830257707,{"v":4.04447636923077e-59,"d":"4.04E-59"},"Up",{"v":4.60808e-61,"d":"4.61E-61"},"CXCL2","GO:0005615//extracellular space;GO:0005576//extracellular region","GO:0045236//CXCR chemokine receptor binding;GO:0008009//chemokine activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0090023//positive regulation of neutrophil chemotaxis;GO:0042127//regulation of cell proliferation;GO:0070098//chemokine-mediated signaling pathway;GO:0032496//response to lipopolysaccharide;GO:0031640//killing of cells of other organism;GO:0002237//response to molecule of bacterial origin;GO:0006954//inflammatory response;GO:0006952//defense response;GO:0006955//immune response;GO:0006935//chemotaxis","K05505//C-X-C motif chemokine 1/2/3","XP_001092240.2//PREDICTED: uncharacterized protein LOC702067 [Macaca mulatta]","3//A2MP1"]
[56301,1962,0.08,0.25,1.64385618977472,0.303963809091877,"*",0.1787362,"SLC7A10","NA","NA","NA","K13782//solute carrier family 7 (L-type amino acid transporter), member 10","XP_019510086.1//PREDICTED: asc-type amino acid transporter 1 [Hipposideros armiger]","2//1"]
[1746,2308,0.69,2.15,1.63966839281129,{"v":1.18776606830514e-05,"d":"1.19E-05"},"Up",{"v":2.32958E-6,"d":"2.33E-06"},"DLX2","NA","NA","NA","K18488//homeobox protein DLX2","XP_003824309.1//PREDICTED: homeobox protein DLX-2 [Pan paniscus]","3//A2MP1"]
[9674,4531,0.3,0.93,1.63226821549951,{"v":3.64888608391608e-05,"d":"3.65E-05"},"Up",{"v":7.8396e-06,"d":"7.84E-06"},"KIAA0040","GO:0016021//integral component of membrane","NA","NA","NA","BAA05022.2//KIAA0040, partial [Homo sapiens]","1//3;2//1"]
[6991,805,0.1,0.31,1.63226821549951,0.529900733049343,"*",0.37379,"TCTE3","GO:0016020//membrane;GO:0005874//microtubule;GO:0030286//dynein complex;GO:0005737//cytoplasm","GO:0003774//motor activity","GO:0006810//transport","K22197//BRG1-associated factor 45A;K18631//tektin-4","XP_017750428.1//PREDICTED: tctex1 domain-containing protein 3 [Rhinopithecus bieti]","2//1"]
[50801,1694,0.1,0.31,1.63226821549951,0.203148088124488,"*",0.1086958,"KCNK4","NA","NA","NA","K04915//potassium channel subfamily K member 4","XP_012633391.1//potassium channel subfamily K member 4 isoform X1 [Microcebus murinus];AAI10328.1//KCNK4 protein, partial [Homo sapiens]","1//3;2//1"]
[10468,1959,0.66,2.04,1.62803122261304,1.02116558480326E-4,"Up",{"v":2.3557e-05,"d":"2.36E-05"},"FST","GO:0005576//extracellular region","GO:0043395//heparan sulfate proteoglycan binding;GO:0048185//activin binding;GO:0004871//signal transducer activity","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0002244//hematopoietic progenitor cell differentiation;GO:0051798//positive regulation of hair follicle development;GO:0032926//negative regulation of activin receptor signaling pathway","K04661//follistatin","EDL18378.1//follistatin, isoform CRA_a, partial [Mus musculus];NP_037541.1//follistatin isoform FST344 precursor [Homo sapiens]","3//A2MP1;2//1"]
[3078,1312,0.39,1.2,1.62148837674627,0.0240033162658847,"*",0.00922326,"CFHR1","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0072562//blood microparticle;GO:0043234//protein complex;GO:0005576//extracellular region","GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity","GO:0030449//regulation of complement activation;GO:0045919//positive regulation of cytolysis;GO:0006956//complement activation;GO:0032091//negative regulation of protein binding","K04004//complement factor H","NP_002104.2//complement factor H-related protein 1 precursor [Homo sapiens]","2//1"]
[200634,932,0.28,0.86,1.61890983264449,0.118382777233655,"*",0.0569014,"KRTCAP3","GO:0016021//integral component of membrane","NA","NA","NA","NP_776252.2//keratinocyte-associated protein 3 [Homo sapiens]","1//3;3//A2MP1"]
[30812,3049,0.29,0.89,1.61775243583883,0.00178090004776119,"*",0.000522876,"SOX8","GO:0005634//nucleus;GO:0044798//nuclear transcription factor complex;GO:0005737//cytoplasm","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0003677//DNA binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0046982//protein heterodimerization activity;GO:0008134//transcription factor binding","GO:0090184//positive regulation of kidney development;GO:0001649//osteoblast differentiation;GO:0046533//negative regulation of photoreceptor cell differentiation;GO:0060221//retinal rod cell differentiation;GO:0008584//male gonad development;GO:0072034//renal vesicle induction;GO:0045892//negative regulation of transcription, DNA-templated;GO:0007165//signal transduction;GO:0001755//neural crest cell migration;GO:0048709//oligodendrocyte differentiation;GO:0043066//negative regulation of apoptotic process;GO:0048469//cell maturation;GO:0035914//skeletal muscle cell differentiation;GO:0045662//negative regulation of myoblast differentiation;GO:0090190//positive regulation of branching involved in ureteric bud morphogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007422//peripheral nervous system development;GO:0033690//positive regulation of osteoblast proliferation;GO:0060041//retina development in camera-type eye;GO:0072197//ureter morphogenesis;GO:0060018//astrocyte fate commitment;GO:0007283//spermatogenesis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0072289//metanephric nephron tubule formation;GO:0045165//cell fate commitment;GO:0014015//positive regulation of gliogenesis;GO:0061138//morphogenesis of a branching epithelium;GO:0006351//transcription, DNA-templated;GO:0001701//in utero embryonic development;GO:0060612//adipose tissue development;GO:0060009//Sertoli cell development;GO:0048484//enteric nervous system development;GO:0010817//regulation of hormone levels;GO:0045444//fat cell differentiation","K09270//transcription factor SOX7/8/10/18 (SOX group E/F)","CAB75612.1//c394H11.1 (similar to SOX (SRY (sex determining region Y))) [Homo sapiens]",4]
[28951,4408,0.16,0.49,1.61470984411521,0.00749389215671642,"*",2.51454E-3,"TRIB2","GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0031434//mitogen-activated protein kinase kinase binding;GO:0005524//ATP binding;GO:0004860//protein kinase inhibitor activity;GO:0004672//protein kinase activity;GO:0031625//ubiquitin protein ligase binding;GO:0055106//ubiquitin-protein transferase regulator activity;GO:0008134//transcription factor binding","GO:0006469//negative regulation of protein kinase activity;GO:0045599//negative regulation of fat cell differentiation;GO:0045081//negative regulation of interleukin-10 biosynthetic process;GO:0043405//regulation of MAP kinase activity;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process","K08814//tribbles homolog 1/2","NP_067675.1//tribbles homolog 2 [Homo sapiens]","3//A2MP1"]
[3665,2009,2.15,6.57,1.61155671073287,{"v":2.72029816496465e-13,"d":"2.72E-13"},"Up",{"v":2.16786e-14,"d":"2.17E-14"},"IRF7","GO:0010008//endosome membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0000982//transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0060337//type I interferon signaling pathway;GO:0034124//regulation of MyD88-dependent toll-like receptor signaling pathway;GO:0032481//positive regulation of type I interferon production;GO:0016064//immunoglobulin mediated immune response;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0032479//regulation of type I interferon production;GO:0032607//interferon-alpha production;GO:0019043//establishment of viral latency;GO:2000110//negative regulation of macrophage apoptotic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006974//cellular response to DNA damage stimulus;GO:0045087//innate immune response;GO:0039530//MDA-5 signaling pathway;GO:0050776//regulation of immune response;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0032728//positive regulation of interferon-beta production;GO:0045351//type I interferon biosynthetic process;GO:0034127//regulation of MyD88-independent toll-like receptor signaling pathway;GO:0045655//regulation of monocyte differentiation;GO:0051607//defense response to virus;GO:0032727//positive regulation of interferon-alpha production;GO:0006351//transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter;GO:0002819//regulation of adaptive immune response;GO:0060340//positive regulation of type I interferon-mediated signaling pathway;GO:0032608//interferon-beta production;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0009615//response to virus","K09447//interferon regulatory factor 7","NP_004020.1//interferon regulatory factor 7 isoform b [Homo sapiens];NP_004022.2//interferon regulatory factor 7 isoform d [Homo sapiens];NP_001563.2//interferon regulatory factor 7 isoform a [Homo sapiens]","3//A2MP1;2//1"]
[100996693,815,0.2,0.61,1.60880924267552,0.303834421496222,"*",0.1787362,"LOC100996693","NA","NA","NA","K12567//titin [EC:2.7.11.1]","XP_010986680.1//PREDICTED: LOW QUALITY PROTEIN: CAVP-target protein [Camelus dromedarius]","1//3"]
[9241,1892,0.21,0.64,1.60768257722124,0.0605717868819374,"*",0.0263044,"NOG","GO:0005615//extracellular space;GO:0005576//extracellular region","GO:0019955//cytokine binding;GO:0042803//protein homodimerization activity","GO:0060044//negative regulation of cardiac muscle cell proliferation;GO:0060272//embryonic skeletal joint morphogenesis;GO:0001649//osteoblast differentiation;GO:0048712//negative regulation of astrocyte differentiation;GO:0060425//lung morphogenesis;GO:0060412//ventricular septum morphogenesis;GO:0061053//somite development;GO:0035019//somatic stem cell population maintenance;GO:0051216//cartilage development;GO:0003149//membranous septum morphogenesis;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0060825//fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation;GO:0061312//BMP signaling pathway involved in heart development;GO:0042474//middle ear morphogenesis;GO:0021533//cell differentiation in hindbrain;GO:0021983//pituitary gland development;GO:0045668//negative regulation of osteoblast differentiation;GO:0003203//endocardial cushion morphogenesis;GO:0003223//ventricular compact myocardium morphogenesis;GO:0048318//axial mesoderm development;GO:0001837//epithelial to mesenchymal transition;GO:0061384//heart trabecula morphogenesis;GO:0009953//dorsal/ventral pattern formation;GO:0030154//cell differentiation;GO:0008045//motor neuron axon guidance;GO:0030509//BMP signaling pathway;GO:0010628//positive regulation of gene expression;GO:0003151//outflow tract morphogenesis;GO:0055009//atrial cardiac muscle tissue morphogenesis;GO:0090190//positive regulation of branching involved in ureteric bud morphogenesis;GO:0060173//limb development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0061037//negative regulation of cartilage development;GO:0045596//negative regulation of cell differentiation;GO:0048706//embryonic skeletal system development;GO:0001843//neural tube closure;GO:0060394//negative regulation of pathway-restricted SMAD protein phosphorylation;GO:0001839//neural plate morphogenesis;GO:0060513//prostatic bud formation;GO:0007399//nervous system development;GO:0030514//negative regulation of BMP signaling pathway;GO:2000313//regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation;GO:0061626//pharyngeal arch artery morphogenesis;GO:0021510//spinal cord development;GO:0001706//endoderm formation;GO:0090193//positive regulation of glomerulus development;GO:0042733//embryonic digit morphogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0001707//mesoderm formation;GO:0060302//negative regulation of cytokine activity;GO:2001234//negative regulation of apoptotic signaling pathway;GO:0042060//wound healing;GO:0001701//in utero embryonic development;GO:0030336//negative regulation of cell migration;GO:0060676//ureteric bud formation;GO:1905006//negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation;GO:0048570//notochord morphogenesis;GO:0060325//face morphogenesis;GO:0001501//skeletal system development;GO:0050679//positive regulation of epithelial cell proliferation","K04658//noggin","XP_007176240.1//PREDICTED: noggin [Balaenoptera acutorostrata scammoni]",4]
[1381,782,0.21,0.64,1.60768257722124,0.304028544223192,"*",0.1787362,"CRABP1","GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0016918//retinal binding;GO:0001972//retinoic acid binding;GO:0005215//transporter activity;GO:0019841//retinol binding;GO:0005501//retinoid binding","GO:0007165//signal transduction;GO:0034653//retinoic acid catabolic process;GO:0007275//multicellular organism development","K17337//cellular retinoic acid-binding protein 1","OWK09030.1//hypothetical protein Celaphus_00015315 [Cervus elaphus hippelaphus]","2//1"]
[5148,1064,0.46,1.39,1.59537911666649,0.0356629181818182,"*",0.0144402,"PDE6G","GO:0097381//photoreceptor disc membrane;GO:0005886//plasma membrane","GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0004857//enzyme inhibitor activity;GO:0047555//3',5'-cyclic-GMP phosphodiesterase activity;GO:0030507//spectrin binding;GO:0030553//cGMP binding","GO:0016056//rhodopsin mediated signaling pathway;GO:0045745//positive regulation of G-protein coupled receptor protein signaling pathway;GO:0000187//activation of MAPK activity;GO:0007223//Wnt signaling pathway, calcium modulating pathway;GO:0007601//visual perception;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0045742//positive regulation of epidermal growth factor receptor signaling pathway","K13759//retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma","XP_006722005.1//PREDICTED: retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma isoform X3 [Homo sapiens]","3//A2MP1"]
[100125288,1997,0.48,1.45,1.59494658929378,0.00157657392330892,"*",0.000458148,"ZGLP1","GO:0005634//nucleus;GO:0005667//transcription factor complex","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0043565//sequence-specific DNA binding;GO:0008270//zinc ion binding;GO:0003700//DNA binding transcription factor activity;GO:0001085//RNA polymerase II transcription factor binding","GO:0048599//oocyte development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0030154//cell differentiation;GO:0007275//multicellular organism development;GO:0007283//spermatogenesis","K21630//GATA-type zinc finger protein 1","NP_001096637.1//GATA-type zinc finger protein 1 [Homo sapiens]","1//3"]
[8365,374,0.48,1.45,1.59494658929378,0.303931451862891,"*",0.1787362,"HIST1H4H","NA","NA","NA","K11254//histone H4","XP_003804484.2//PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein LOC100980546 [Pan paniscus]","3//A2MP1"]
[8789,1367,0.06,0.18,1.58496250072116,0.531599132834758,"*",0.37379,"FBP2","GO:0070062//extracellular exosome;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0042802//identical protein binding;GO:0042132//fructose 1,6-bisphosphate 1-phosphatase activity","GO:0005986//sucrose biosynthetic process;GO:0006002//fructose 6-phosphate metabolic process;GO:0006094//gluconeogenesis;GO:0006000//fructose metabolic process;GO:0005975//carbohydrate metabolic process;GO:0030388//fructose 1,6-bisphosphate metabolic process","K03841//fructose-1,6-bisphosphatase I [EC:3.1.3.11]","XP_012890385.1//PREDICTED: fructose-1,6-bisphosphatase isozyme 2 [Dipodomys ordii]","3//A2MP1"]
[319101,2323,0.01,0.03,1.58496250072116,0.655715815414987,"*",0.499032,"KRT73","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0045095//keratin filament","GO:0005198//structural molecule activity","NA","K07605//type II keratin, basic","XP_019275006.1//PREDICTED: keratin, type II cytoskeletal 73 isoform X1 [Panthera pardus]","2//1"]
[26266,2927,0.01,0.03,1.58496250072116,0.655607958549223,"*",0.499032,"SLC13A4","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0015382//sodium:sulfate symporter activity;GO:0005215//transporter activity","GO:0055085//transmembrane transport;GO:0008272//sulfate transport;GO:0006814//sodium ion transport;GO:0098656//anion transmembrane transport","K14444//solute carrier family 13 (sodium/sulfate cotransporter), member 1/4","NP_036582.2//solute carrier family 13 member 4 isoform 2 [Homo sapiens];NP_001305121.1//solute carrier family 13 member 4 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[2543,3014,0.01,0.03,1.58496250072116,0.655338471555409,"*",0.499032,"GAGE1","NA","NA","NA","K11447//histone demethylase [EC:1.14.11.-];K01064//wingless-type MMTV integration site family, member 9","NP_001035753.1//G antigen 1 [Homo sapiens]","2//1"]
[4481,2960,0.01,0.03,1.58496250072116,0.655230738780207,"*",0.499032,"MSR1","GO:0016021//integral component of membrane","GO:0005044//scavenger receptor activity","NA","K16628//collagen, type VII, alpha;K19721//collagen, type V/XI/XXIV/XXVII, alpha;K06558//macrophage scavenger receptor 1","XP_004940504.1//PREDICTED: collagen alpha-1(XIX) chain isoform X1 [Gallus gallus];XP_008061454.1//macrophage scavenger receptor types I and II isoform X1 [Carlito syrichta];XP_015714626.1//PREDICTED: collagen alpha-1(XIX) chain isoform X4 [Coturnix japonica]","3//A2MP1;2//1"]
[3270,2430,0.01,0.03,1.58496250072116,0.655123041420118,"*",0.499032,"HRC","GO:0005788//endoplasmic reticulum lumen;GO:0030018//Z disc;GO:0033018//sarcoplasmic reticulum lumen;GO:0033017//sarcoplasmic reticulum membrane","GO:0044325//ion channel binding;GO:0005509//calcium ion binding;GO:0051117//ATPase binding","GO:0043687//post-translational protein modification;GO:1901899//positive regulation of relaxation of cardiac muscle;GO:1901844//regulation of cell communication by electrical coupling involved in cardiac conduction;GO:0010460//positive regulation of heart rate;GO:0006936//muscle contraction;GO:0045823//positive regulation of heart contraction;GO:0033135//regulation of peptidyl-serine phosphorylation;GO:0002027//regulation of heart rate;GO:0051480//regulation of cytosolic calcium ion concentration;GO:1903169//regulation of calcium ion transmembrane transport;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0044267//cellular protein metabolic process;GO:0051481//negative regulation of cytosolic calcium ion concentration;GO:0060314//regulation of ryanodine-sensitive calcium-release channel activity;GO:0010881//regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion;GO:1902081//negative regulation of calcium ion import into sarcoplasmic reticulum","K19607//X-linked retinitis pigmentosa GTPase regulator","NP_002143.1//sarcoplasmic reticulum histidine-rich calcium-binding protein precursor [Homo sapiens]","2//1"]
[79781,3155,0.01,0.03,1.58496250072116,0.654961561745132,"*",0.499032,"IQCA1","NA","GO:0005524//ATP binding","NA","K13254//spastin [EC:3.6.4.3];K00665//fatty acid synthase, animal type [EC:2.3.1.85];K19607//X-linked retinitis pigmentosa GTPase regulator","NP_001257514.1//IQ and AAA domain-containing protein 1 isoform 3 [Homo sapiens];NP_079002.3//IQ and AAA domain-containing protein 1 isoform 1 [Homo sapiens];NP_001257513.1//IQ and AAA domain-containing protein 1 isoform 2 [Homo sapiens]","4;1//3"]
[51285,2606,0.01,0.03,1.58496250072116,0.654638841093865,"*",0.499032,"RASL12","GO:0016020//membrane","GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0007165//signal transduction","K07854//Ras-like protein family member 12","XP_011795786.1//PREDICTED: ras-like protein family member 12 isoform X1 [Colobus angolensis palliatus];XP_011795787.1//PREDICTED: ras-like protein family member 12 isoform X2 [Colobus angolensis palliatus]","1//3;3//A2MP1"]
[148345,2779,0.01,0.03,1.58496250072116,0.654585085235671,"*",0.499032,"C1orf127","NA","NA","NA","K10955//mucin-2;K22020//mucin-19","NP_001164225.1//uncharacterized protein C1orf127 precursor [Homo sapiens]","1//3"]
[5275,3124,0.01,0.03,1.58496250072116,0.654531338205107,"*",0.499032,"SERPINB13","GO:0070062//extracellular exosome;GO:0005654//nucleoplasm;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0043202//lysosomal lumen;GO:0005737//cytoplasm","GO:0002020//protease binding;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0004869//cysteine-type endopeptidase inhibitor activity","GO:0045616//regulation of keratinocyte differentiation;GO:0010951//negative regulation of endopeptidase activity;GO:0009411//response to UV;GO:0030162//regulation of proteolysis;GO:1902173//negative regulation of keratinocyte apoptotic process","K13963//serpin B","XP_004059557.2//PREDICTED: serpin B13 isoform X1 [Gorilla gorilla gorilla];NP_001335197.1//serpin B13 isoform 3 [Homo sapiens];XP_009432379.1//PREDICTED: serpin B13 isoform X1 [Pan troglodytes];XP_011524331.1//PREDICTED: serpin B13 isoform X1 [Homo sapiens]","1//3;3//A2MP1"]
[11174,7332,0.01,0.03,1.58496250072116,0.531362593218831,"*",0.37379,"ADAMTS6","GO:0005578//proteinaceous extracellular matrix","GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding","NA","K08621//a disintegrin and metalloproteinase with thrombospondin motifs 6 [EC:3.4.24.-]","NP_922932.2//A disintegrin and metalloproteinase with thrombospondin motifs 6 preproprotein [Homo sapiens]","3//A2MP1"]
[18,4814,0.01,0.03,1.58496250072116,0.395383067818489,"*",0.249274,"ABAT","NA","NA","NA","K13524//4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase [EC:2.6.1.19 2.6.1.22]","BAH11640.1//unnamed protein product [Homo sapiens];XP_007983271.1//PREDICTED: 4-aminobutyrate aminotransferase, mitochondrial isoform X1 [Chlorocebus sabaeus]","4;1//3;5"]
[11131,2754,0.01,0.03,1.58496250072116,0.653887061602822,"*",0.499032,"CAPN11","NA","NA","NA","K08580//calpain-11 [EC:3.4.22.-]","XP_016810152.1//PREDICTED: calpain-11 isoform X2 [Pan troglodytes]","3//A2MP1"]
[2793,930,0.09,0.27,1.58496250072116,0.531220770462633,"*",0.37379,"GNGT2","NA","NA","NA","K04549//guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2","XP_014422610.1//PREDICTED: guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 isoform X2 [Camelus ferus]","1//3;2//1"]
[399697,2695,0.01,0.03,1.58496250072116,0.653458248053119,"*",0.499032,"CTXN2","GO:0016021//integral component of membrane","NA","NA","NA","XP_005376763.1//PREDICTED: cortexin-2 [Chinchilla lanigera]","1//3"]
[83483,2319,0.01,0.03,1.58496250072116,0.652976504587156,"*",0.499032,"PLVAP","GO:0070062//extracellular exosome;GO:0009986//cell surface;GO:0005901//caveola;GO:0005622//intracellular;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm","GO:0042803//protein homodimerization activity","GO:0000165//MAPK cascade;GO:0002693//positive regulation of cellular extravasation;GO:0033209//tumor necrosis factor-mediated signaling pathway","K17309//plasmalemma vesicle-associated protein","NP_112600.1//plasmalemma vesicle-associated protein [Homo sapiens]","2//1"]
[644353,2951,0.01,0.03,1.58496250072116,0.652442066459322,"*",0.499032,"ZCCHC18","GO:0016607//nuclear speck","GO:0008270//zinc ion binding;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0003676//nucleic acid binding","GO:0030509//BMP signaling pathway","K12015//tripartite motif-containing protein 39 [EC:2.3.2.27]","NP_001137450.1//zinc finger CCHC domain-containing protein 18 [Homo sapiens]","2//1"]
[256006,6036,0.01,0.03,1.58496250072116,0.735367718863049,"*",0.623548,"ANKRD31","NA","NA","NA","K09663//beta-1,6-N-acetylglucosaminyltransferase 4 [EC:2.4.1.-];K21436//ankyrin repeat domain-containing protein 11/12","NP_001157915.1//putative ankyrin repeat domain-containing protein 31 [Homo sapiens]","1//3"]
[9535,668,0.15,0.45,1.58496250072116,0.531079023392333,"*",0.37379,"GMFG","GO:0034774//secretory granule lumen;GO:0005622//intracellular;GO:1904813//ficolin-1-rich granule lumen;GO:0005576//extracellular region","GO:0003779//actin binding;GO:0008083//growth factor activity;GO:0004860//protein kinase inhibitor activity;GO:0008047//enzyme activator activity;GO:0071933//Arp2/3 complex binding","GO:0034316//negative regulation of Arp2/3 complex-mediated actin nucleation;GO:0071846//actin filament debranching;GO:0006468//protein phosphorylation;GO:0043312//neutrophil degranulation;GO:2000249//regulation of actin cytoskeleton reorganization","K20368//protein cornichon","XP_012630098.1//glia maturation factor gamma [Microcebus murinus];XP_008580296.1//PREDICTED: glia maturation factor gamma isoform X3 [Galeopterus variegatus]","1//3;3//A2MP1"]
[5017,3039,0.01,0.03,1.58496250072116,0.651588782736636,"*",0.499032,"OVOL1","GO:0005634//nucleus","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0007498//mesoderm development;GO:0043588//skin development;GO:0001822//kidney development;GO:0006351//transcription, DNA-templated;GO:0007283//spermatogenesis;GO:1901994//negative regulation of meiotic cell cycle phase transition;GO:0008544//epidermis development;GO:2000647//negative regulation of stem cell proliferation;GO:0051729//germline cell cycle switching, mitotic to meiotic cell cycle","K09216//ovo","XP_002821563.3//PREDICTED: putative transcription factor Ovo-like 1 [Pongo abelii]","3//A2MP1"]
[4018,6489,0.01,0.03,1.58496250072116,0.735259153465712,"*",0.623548,"LPA","NA","NA","NA","K09644//apolipoprotein(a) [EC:3.4.21.-]","NP_005568.2//apolipoprotein(a) precursor [Homo sapiens]","2//1"]
[8796,3180,0.01,0.03,1.58496250072116,0.651269376470588,"*",0.499032,"SCEL","GO:0070062//extracellular exosome;GO:0001533//cornified envelope;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm","GO:0046872//metal ion binding","GO:0009612//response to mechanical stimulus;GO:0008544//epidermis development;GO:0030216//keratinocyte differentiation;GO:0009790//embryo development;GO:0090263//positive regulation of canonical Wnt signaling pathway","K06084//F-box protein 20;K16580//SLAIN motif-containing protein 1/2","NP_001154178.1//sciellin isoform 3 [Homo sapiens];NP_659001.2//sciellin isoform 1 [Homo sapiens];NP_003834.3//sciellin isoform 2 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[6196,5692,0.01,0.03,1.58496250072116,0.394521240067373,"*",0.249274,"RPS6KA2","GO:0005840//ribosome;GO:0005634//nucleus;GO:0005819//spindle;GO:0005737//cytoplasm","GO:0000287//magnesium ion binding;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0004711//ribosomal protein S6 kinase activity","GO:0002035//brain renin-angiotensin system;GO:0045786//negative regulation of cell cycle;GO:0010659//cardiac muscle cell apoptotic process;GO:0007507//heart development;GO:0006468//protein phosphorylation;GO:0001556//oocyte maturation;GO:0035556//intracellular signal transduction;GO:0010628//positive regulation of gene expression;GO:0070613//regulation of protein processing;GO:0043065//positive regulation of apoptotic process;GO:0071322//cellular response to carbohydrate stimulus;GO:0045835//negative regulation of meiotic nuclear division;GO:0018105//peptidyl-serine phosphorylation;GO:0060047//heart contraction;GO:0008285//negative regulation of cell proliferation","K04373//ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]","NP_001179407.1//ribosomal protein S6 kinase alpha-2 [Bos taurus];DAA25952.1//TPA: ribosomal protein S6 kinase, 90kDa, polypeptide 2 isoform 2 [Bos taurus];XP_017363792.1//PREDICTED: ribosomal protein S6 kinase alpha-2 isoform X1 [Cebus capucinus imitator]","1//3;2//1;5"]
[114569,2831,0.01,0.03,1.58496250072116,0.650525311571732,"*",0.499032,"MAL2","GO:0070062//extracellular exosome;GO:0012505//endomembrane system;GO:0045121//membrane raft;GO:0016324//apical plasma membrane;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm","GO:0019911//structural constituent of myelin sheath","GO:0042552//myelination;GO:0001766//membrane raft polarization;GO:0008104//protein localization;GO:0045056//transcytosis","NA","NP_443118.1//protein MAL2 [Homo sapiens]","2//1"]
[8404,2932,0.01,0.03,1.58496250072116,0.650472229130967,"*",0.499032,"SPARCL1","GO:0070062//extracellular exosome;GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix","GO:0005518//collagen binding;GO:0005509//calcium ion binding;GO:0050840//extracellular matrix binding","GO:0043687//post-translational protein modification;GO:0044267//cellular protein metabolic process;GO:0007165//signal transduction;GO:0048856//anatomical structure development","K10402//kinesin family member 20;K19607//X-linked retinitis pigmentosa GTPase regulator","NP_001121782.1//SPARC-like protein 1 isoform 1 precursor [Homo sapiens]","1//3;2//1;5"]
[4593,2466,0.01,0.03,1.58496250072116,0.65041915535248,"*",0.499032,"MUSK","GO:0005887//integral component of plasma membrane;GO:0031594//neuromuscular junction;GO:0030054//cell junction;GO:0043235//receptor complex;GO:0045211//postsynaptic membrane","GO:0004713//protein tyrosine kinase activity;GO:0046872//metal ion binding;GO:0005524//ATP binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity","GO:0007528//neuromuscular junction development;GO:0030154//cell differentiation;GO:2000541//positive regulation of protein geranylgeranylation;GO:0010628//positive regulation of gene expression;GO:0046777//protein autophosphorylation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007613//memory;GO:0007275//multicellular organism development;GO:0008582//regulation of synaptic growth at neuromuscular junction;GO:0001934//positive regulation of protein phosphorylation;GO:0071340//skeletal muscle acetylcholine-gated channel clustering","K05129//muscle, skeletal, receptor tyrosine kinase [EC:2.7.10.1]","NP_001159752.1//muscle, skeletal receptor tyrosine-protein kinase isoform 2 [Homo sapiens];NP_001159753.1//muscle, skeletal receptor tyrosine-protein kinase isoform 3 [Homo sapiens];NP_005583.1//muscle, skeletal receptor tyrosine-protein kinase isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[1006,4962,0.01,0.03,1.58496250072116,0.394130740968029,"*",0.249274,"CDH8","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005509//calcium ion binding","GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules","K06800//cadherin 8, type 2","XP_019610595.1//PREDICTED: cadherin-8 isoform X1 [Rhinolophus sinicus]",4]
[284898,2407,0.01,0.03,1.58496250072116,0.650259985969492,"*",0.499032,"LOC284898","NA","NA","NA","NA","NP_001305258.1//uncharacterized protein LOC284898 precursor [Homo sapiens]","1//3"]
[5317,5384,0.01,0.03,1.58496250072116,0.734987880165289,"*",0.623548,"PKP1","GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0101003//ficolin-1-rich granule membrane;GO:0001533//cornified envelope;GO:0005882//intermediate filament;GO:0005886//plasma membrane;GO:1990124//messenger ribonucleoprotein complex;GO:0030057//desmosome","GO:0030280//structural constituent of epidermis;GO:0004871//signal transducer activity;GO:0019215//intermediate filament binding;GO:0005521//lamin binding","GO:0045110//intermediate filament bundle assembly;GO:1902373//negative regulation of mRNA catabolic process;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0043312//neutrophil degranulation;GO:0031424//keratinization;GO:0010628//positive regulation of gene expression;GO:0070268//cornification","K10387//plakophilin 1","NP_000290.2//plakophilin-1 isoform 1b [Homo sapiens];NP_001005337.1//plakophilin-1 isoform 1a [Homo sapiens]","3//A2MP1;2//1"]
[93034,2898,0.01,0.03,1.58496250072116,0.649994876712329,"*",0.499032,"NT5C1B","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0000287//magnesium ion binding;GO:0008253//5'-nucleotidase activity;GO:0000166//nucleotide binding","GO:0006195//purine nucleotide catabolic process;GO:0009117//nucleotide metabolic process","K01081//5'-nucleotidase [EC:3.1.3.5]","AAK39108.1//autoimmune infertility-related protein, partial [Homo sapiens];NP_001186016.1//cytosolic 5'-nucleotidase 1B isoform 4 [Homo sapiens];NP_001186017.1//cytosolic 5'-nucleotidase 1B isoform 5 [Homo sapiens];NP_001186015.1//cytosolic 5'-nucleotidase 1B isoform 3 [Homo sapiens];NP_001002006.1//cytosolic 5'-nucleotidase 1B isoform 1 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[51209,3802,0.02,0.06,1.58496250072116,0.530937351947359,"*",0.37379,"RAB9B","NA","NA","NA","K07900//Ras-related protein Rab-9B","XP_008508240.1//PREDICTED: ras-related protein Rab-9B isoform X1 [Equus przewalskii]","3//A2MP1"]
[283777,3298,0.01,0.03,1.58496250072116,0.649888893526822,"*",0.499032,"FAM169B","NA","NA","NA","K19464//pleckstrin homology domain-containing family G member 5;K12869//crooked neck","XP_009428176.2//PREDICTED: protein FAM169B [Pan troglodytes]","2//1"]
[283685,3151,0.01,0.03,1.58496250072116,0.649518224395013,"*",0.499032,"GOLGA6L2","GO:0005794//Golgi apparatus","NA","NA","K20358//golgin subfamily A member 2","NP_001291317.1//golgin subfamily A member 6-like protein 2 [Homo sapiens]","1//3"]
[645121,2594,0.03,0.09,1.58496250072116,0.530842946301565,"*",0.37379,"CCNI2","NA","NA","NA","K16939//septin 6/8/11","NP_001034869.1//cyclin-I2 isoform 2 [Homo sapiens];NP_001274182.1//cyclin-I2 isoform 3 [Homo sapiens];NP_001274181.1//cyclin-I2 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[57556,6950,0.01,0.03,1.58496250072116,0.226669876740741,"*",0.1245166,"SEMA6A","GO:0030424//axon;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane","GO:0030215//semaphorin receptor binding;GO:0004888//transmembrane signaling receptor activity","GO:0007399//nervous system development;GO:0007166//cell surface receptor signaling pathway;GO:0006915//apoptotic process;GO:0009887//animal organ morphogenesis;GO:0051642//centrosome localization;GO:0001764//neuron migration;GO:0007010//cytoskeleton organization;GO:0071526//semaphorin-plexin signaling pathway;GO:0007411//axon guidance;GO:2001224//positive regulation of neuron migration","K06842//semaphorin 6","NP_065847.1//semaphorin-6A isoform 2 precursor [Homo sapiens];NP_001287709.1//semaphorin-6A isoform 1 precursor [Homo sapiens]","1//3;4"]
[115350,2989,0.01,0.03,1.58496250072116,0.648883774358974,"*",0.499032,"FCRL1","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","NA","NA","K06727//Fc receptor-like protein","NP_001152870.1//Fc receptor-like protein 1 isoform 3 precursor [Homo sapiens];NP_001152869.1//Fc receptor-like protein 1 isoform 2 precursor [Homo sapiens];NP_443170.1//Fc receptor-like protein 1 isoform 1 precursor [Homo sapiens]","1//3;4"]
[134111,6129,0.01,0.03,1.58496250072116,0.734716806963192,"*",0.623548,"UBE2QL1","GO:0005634//nucleus;GO:0005886//plasma membrane","GO:0005524//ATP binding;GO:0061631//ubiquitin conjugating enzyme activity","NA","K10582//ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]","XP_007959358.1//PREDICTED: ubiquitin-conjugating enzyme E2Q-like protein 1 [Chlorocebus sabaeus]","2//1"]
[151126,2645,0.01,0.03,1.58496250072116,0.64872535546875,"*",0.499032,"ZNF385B","GO:0001650//fibrillar center","GO:0002039//p53 binding;GO:0008270//zinc ion binding;GO:0003676//nucleic acid binding","GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator","K10137//zinc finger, matrin type 3","NP_001339738.1//zinc finger protein 385B isoform 4 [Homo sapiens];NP_001339745.1//zinc finger protein 385B isoform 8 [Homo sapiens];NP_001339740.1//zinc finger protein 385B isoform 6 [Homo sapiens];XP_012641285.1//zinc finger protein 385B isoform X4 [Microcebus murinus];XP_021570045.1//zinc finger protein 385B isoform X4 [Carlito syrichta];NP_001339741.1//zinc finger protein 385B isoform 7 [Homo sapiens];NP_689733.4//zinc finger protein 385B isoform 1 [Homo sapiens];NP_001339739.1//zinc finger protein 385B isoform 5 [Homo sapiens]","1//3;2//1;5"]
[140893,2853,0.01,0.03,1.58496250072116,0.648619785842148,"*",0.499032,"RBBP8NL","GO:0005615//extracellular space","NA","NA","K20773//DNA endonuclease RBBP8 [EC:3.1.-.-]","XP_016792691.1//PREDICTED: RBBP8 N-terminal-like protein isoform X1 [Pan troglodytes]","2//1"]
[84911,2819,0.01,0.03,1.58496250072116,0.648461495810624,"*",0.499032,"ZNF382","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_020727394.1//zinc finger protein 382 isoform X4 [Odocoileus virginianus texanus]","4;1//3"]
[60494,2518,0.01,0.03,1.58496250072116,0.648408749633968,"*",0.499032,"CCDC81","GO:0005813//centrosome;GO:0005737//cytoplasm","GO:0003677//DNA binding","NA","K14165//atypical dual specificity phosphatase [EC:3.1.3.16 3.1.3.48];K12875//apoptotic chromatin condensation inducer in the nucleus;K04257//olfactory receptor;K18626//trichohyalin","NP_001149946.1//coiled-coil domain-containing protein 81 isoform 1 [Homo sapiens];NP_068599.3//coiled-coil domain-containing protein 81 isoform 2 [Homo sapiens]","1//3;4"]
[1008,2950,0.01,0.03,1.58496250072116,0.648250562576238,"*",0.499032,"CDH10","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005509//calcium ion binding","GO:0098609//cell-cell adhesion;GO:0034332//adherens junction organization;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules","K06802//cadherin 10, type 2, T2-cadherin","NP_006718.2//cadherin-10 isoform 1 preproprotein [Homo sapiens];XP_007534593.1//PREDICTED: cadherin-10 isoform X1 [Erinaceus europaeus];XP_016048640.1//PREDICTED: cadherin-10 isoform X2 [Erinaceus europaeus]","1//3;4"]
[57540,5231,0.01,0.03,1.58496250072116,0.393741014140216,"*",0.249274,"DISP3","GO:0031965//nuclear membrane;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005737//cytoplasm;GO:0030659//cytoplasmic vesicle membrane","NA","GO:2000179//positive regulation of neural precursor cell proliferation;GO:0045665//negative regulation of neuron differentiation;GO:0008203//cholesterol metabolic process;GO:0042632//cholesterol homeostasis;GO:0007224//smoothened signaling pathway;GO:0045834//positive regulation of lipid metabolic process;GO:0032368//regulation of lipid transport","K10955//mucin-2;K18730//PERQ amino acid-rich with GYF domain-containing protein","NP_065831.1//protein dispatched homolog 3 [Homo sapiens]","1//3"]
[166979,2858,0.01,0.03,1.58496250072116,0.647723829365402,"*",0.499032,"CDC20B","NA","GO:0097027//ubiquitin-protein transferase activator activity;GO:0010997//anaphase-promoting complex binding","GO:1904668//positive regulation of ubiquitin protein ligase activity","K03363//cell division cycle 20, cofactor of APC complex","NP_689836.2//cell division cycle protein 20 homolog B isoform 1 [Homo sapiens];NP_001163873.1//cell division cycle protein 20 homolog B isoform 3 [Homo sapiens];NP_001139206.2//cell division cycle protein 20 homolog B isoform 2 [Homo sapiens]","1//3;2//1"]
[140689,3107,0.01,0.03,1.58496250072116,0.647671203119922,"*",0.499032,"CBLN4","GO:0005615//extracellular space;GO:0030054//cell junction;GO:0045202//synapse","NA","GO:0009306//protein secretion","K18744//caprin-2","XP_015335073.1//PREDICTED: cerebellin-4 [Marmota marmota marmota]",5]
[6716,2446,0.01,0.03,1.58496250072116,0.647513375680286,"*",0.499032,"SRD5A2","GO:0016021//integral component of membrane;GO:0005737//cytoplasm","GO:0030283//testosterone dehydrogenase [NAD(P)] activity;GO:0009917//sterol 5-alpha reductase activity;GO:0003865//3-oxo-5-alpha-steroid 4-dehydrogenase activity","GO:0061370//testosterone biosynthetic process;GO:0030539//male genitalia development;GO:0008584//male gonad development;GO:0006702//androgen biosynthetic process","K12344//3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:1.3.1.22]","XP_003262754.2//PREDICTED: 3-oxo-5-alpha-steroid 4-dehydrogenase 2 [Nomascus leucogenys]","3//A2MP1"]
[9081,1238,0.01,0.03,1.58496250072116,0.999783057762185,"*",0.999032,"PRY","NA","NA","NA","K07899//Ras-related protein Rab-9A","NP_004667.2//PTPN13-like protein, Y-linked [Homo sapiens]","2//1"]
[2769,2311,0.01,0.03,1.58496250072116,0.647303058708892,"*",0.499032,"GNA15","GO:0005834//heterotrimeric G-protein complex;GO:0005886//plasma membrane","GO:0031683//G-protein beta/gamma-subunit complex binding;GO:0046872//metal ion binding;GO:0001664//G-protein coupled receptor binding;GO:0004871//signal transducer activity;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0007202//activation of phospholipase C activity;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0030168//platelet activation;GO:0060158//phospholipase C-activating dopamine receptor signaling pathway;GO:0007207//phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway","K04637//guanine nucleotide-binding protein subunit alpha-15","NP_002059.3//guanine nucleotide-binding protein subunit alpha-15 [Homo sapiens]","3//A2MP1"]
[94240,3194,0.01,0.03,1.58496250072116,0.647250500811952,"*",0.499032,"EPSTI1","NA","NA","NA","K18730//PERQ amino acid-rich with GYF domain-containing protein;K20045//intersectin","NP_001317472.1//epithelial-stromal interaction protein 1 isoform 3 [Homo sapiens];NP_001002264.1//epithelial-stromal interaction protein 1 isoform 1 [Homo sapiens];NP_150280.1//epithelial-stromal interaction protein 1 isoform 2 [Homo sapiens]","4;1//3;3//A2MP1"]
[94026,3170,0.01,0.03,1.58496250072116,0.647092878318045,"*",0.499032,"POM121L2","GO:0005622//intracellular","GO:0005487//nucleocytoplasmic transporter activity;GO:0017056//structural constituent of nuclear pore;GO:0008139//nuclear localization sequence binding","GO:0006606//protein import into nucleus;GO:0006405//RNA export from nucleus","K14316//nuclear pore complex protein Nup121","NP_258443.2//POM121-like protein 2 [Homo sapiens]","3//A2MP1"]
[23349,5850,0.01,0.03,1.58496250072116,0.393274358123457,"*",0.249274,"PHF24","NA","GO:0005509//calcium ion binding","GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0007214//gamma-aminobutyric acid signaling pathway;GO:0050966//detection of mechanical stimulus involved in sensory perception of pain;GO:0032228//regulation of synaptic transmission, GABAergic","K09291//nucleoprotein TPR;K10367//formin 1;K20638//Rho GTPase-activating protein 17","XP_011516129.1//PREDICTED: PHD finger protein 24 isoform X1 [Homo sapiens];XP_004048026.2//PREDICTED: PHD finger protein 24 isoform X2 [Gorilla gorilla gorilla]","1//3;2//1"]
[3818,2234,0.01,0.03,1.58496250072116,0.646463155299651,"*",0.499032,"KLKB1","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0004252//serine-type endopeptidase activity","GO:0042730//fibrinolysis;GO:0002542//Factor XII activation;GO:0022617//extracellular matrix disassembly;GO:0006508//proteolysis;GO:0051919//positive regulation of fibrinolysis;GO:0007597//blood coagulation, intrinsic pathway;GO:0031638//zymogen activation;GO:0031639//plasminogen activation","K01324//plasma kallikrein [EC:3.4.21.34]","NP_000883.2//plasma kallikrein isoform 1 preproprotein [Homo sapiens];NP_001305325.1//plasma kallikrein isoform 3 precursor [Homo sapiens];XP_016863672.1//PREDICTED: plasma kallikrein isoform X3 [Homo sapiens]","4;1//3"]
[7173,2930,0.01,0.03,1.58496250072116,0.64630591600454,"*",0.499032,"TPO","GO:0005615//extracellular space;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005886//plasma membrane","GO:0020037//heme binding;GO:0004601//peroxidase activity;GO:0005509//calcium ion binding;GO:0004447//iodide peroxidase activity","GO:0006979//response to oxidative stress;GO:0042446//hormone biosynthetic process;GO:0035162//embryonic hemopoiesis;GO:0006590//thyroid hormone generation;GO:0042744//hydrogen peroxide catabolic process","K00431//thyroid peroxidase [EC:1.11.1.8]","NP_000538.3//thyroid peroxidase isoform a precursor [Homo sapiens];NP_783650.1//thyroid peroxidase isoform b precursor [Homo sapiens];NP_783653.1//thyroid peroxidase isoform e precursor [Homo sapiens];NP_783652.1//thyroid peroxidase isoform d precursor [Homo sapiens]","1//3;3//A2MP1;5"]
[55170,2665,0.01,0.03,1.58496250072116,0.646148753181487,"*",0.499032,"PRMT6","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol","GO:0042393//histone binding;GO:0035242//protein-arginine omega-N asymmetric methyltransferase activity;GO:0008469//histone-arginine N-methyltransferase activity;GO:0042054//histone methyltransferase activity;GO:0016274//protein-arginine N-methyltransferase activity;GO:0044020//histone methyltransferase activity (H4-R3 specific);GO:0070612//histone methyltransferase activity (H2A-R3 specific);GO:0003682//chromatin binding;GO:0035241//protein-arginine omega-N monomethyltransferase activity;GO:0070611//histone methyltransferase activity (H3-R2 specific)","GO:0045892//negative regulation of transcription, DNA-templated;GO:0016571//histone methylation;GO:0006284//base-excision repair;GO:0006355//regulation of transcription, DNA-templated;GO:0034970//histone H3-R2 methylation;GO:0006351//transcription, DNA-templated;GO:0016032//viral process;GO:0045652//regulation of megakaryocyte differentiation;GO:0016049//cell growth;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0090398//cellular senescence;GO:0019919//peptidyl-arginine methylation, to asymmetrical-dimethyl arginine","K11437//type I protein arginine methyltransferase [EC:2.1.1.319]","XP_017830473.1//PREDICTED: protein arginine N-methyltransferase 6 [Callithrix jacchus]","2//1"]
[78997,2585,0.01,0.03,1.58496250072116,0.646044020423049,"*",0.499032,"GDAP1L1","GO:0016021//integral component of membrane;GO:0005737//cytoplasm","GO:0004364//glutathione transferase activity","GO:0006749//glutathione metabolic process","K22077//ganglioside-induced differentiation-associated protein 1","NP_001243668.1//ganglioside-induced differentiation-associated protein 1-like 1 isoform 4 [Homo sapiens];NP_001243669.1//ganglioside-induced differentiation-associated protein 1-like 1 isoform 5 [Homo sapiens];NP_001243666.1//ganglioside-induced differentiation-associated protein 1-like 1 isoform 1 [Homo sapiens];NP_076939.3//ganglioside-induced differentiation-associated protein 1-like 1 isoform 2 [Homo sapiens]","4;1//3"]
[81492,2484,0.01,0.03,1.58496250072116,0.645991666774716,"*",0.499032,"RSPH6A","NA","NA","NA","K06100//symplekin;K19756//radial spoke head protein 4A","XP_011935961.1//PREDICTED: radial spoke head protein 6 homolog A isoform X1 [Cercocebus atys]","3//A2MP1"]
[695,2767,0.01,0.03,1.58496250072116,0.64583465672851,"*",0.499032,"BTK","GO:0005634//nucleus;GO:0031410//cytoplasmic vesicle;GO:0005622//intracellular;GO:0042629//mast cell granule;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0045121//membrane raft;GO:0005829//cytosol;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0005886//plasma membrane","GO:0004713//protein tyrosine kinase activity;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0046872//metal ion binding;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0005102//receptor binding","GO:0001812//positive regulation of type I hypersensitivity;GO:0038083//peptidyl-tyrosine autophosphorylation;GO:0034614//cellular response to reactive oxygen species;GO:0097190//apoptotic signaling pathway;GO:0042127//regulation of cell proliferation;GO:0035556//intracellular signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0071226//cellular response to molecule of fungal origin;GO:0001818//negative regulation of cytokine production;GO:0045087//innate immune response;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0050853//B cell receptor signaling pathway;GO:0098761//cellular response to interleukin-7;GO:0007498//mesoderm development;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0002553//histamine secretion by mast cell;GO:0006468//protein phosphorylation;GO:0019722//calcium-mediated signaling;GO:0006351//transcription, DNA-templated;GO:0045579//positive regulation of B cell differentiation;GO:0001805//positive regulation of type III hypersensitivity;GO:0002250//adaptive immune response;GO:0048469//cell maturation;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0002721//regulation of B cell cytokine production;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0002344//B cell affinity maturation;GO:0002902//regulation of B cell apoptotic process;GO:0030889//negative regulation of B cell proliferation;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0042113//B cell activation","K07370//Bruton agammaglobulinemia tyrosine kinase [EC:2.7.10.2]","NP_001274273.1//tyrosine-protein kinase BTK isoform 3 [Homo sapiens];NP_001274274.1//tyrosine-protein kinase BTK isoform 2 [Homo sapiens];XP_011820173.1//PREDICTED: tyrosine-protein kinase BTK isoform X1 [Mandrillus leucophaeus]","1//3;2//1"]
[11063,2177,0.01,0.03,1.58496250072116,0.645782337005833,"*",0.499032,"SOX30","GO:0005634//nucleus","GO:0003677//DNA binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding","GO:0031960//response to corticosteroid;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0007283//spermatogenesis","K09271//transcription factor SOX15/30","NP_848511.1//transcription factor SOX-30 isoform a [Homo sapiens];NP_001295094.1//transcription factor SOX-30 isoform c [Homo sapiens];NP_008948.1//transcription factor SOX-30 isoform b [Homo sapiens]","1//3;2//1"]
[163059,2343,0.01,0.03,1.58496250072116,0.645730025759417,"*",0.499032,"ZNF433","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","NP_001295277.1//zinc finger protein 433 isoform 3 [Homo sapiens];NP_001073880.1//zinc finger protein 433 isoform 1 [Homo sapiens]","1//3;2//1"]
[9718,3162,0.01,0.03,1.58496250072116,0.645155160893493,"*",0.499032,"ECE2","GO:0016021//integral component of membrane","GO:0004222//metalloendopeptidase activity","GO:0016486//peptide hormone processing","K01415//endothelin-converting enzyme [EC:3.4.24.71]","XP_021586018.1//endothelin-converting enzyme 2 isoform X1 [Ictidomys tridecemlineatus];XP_005331107.1//endothelin-converting enzyme 2 isoform X3 [Ictidomys tridecemlineatus];XP_005331106.1//endothelin-converting enzyme 2 isoform X2 [Ictidomys tridecemlineatus]","1//3;2//1"]
[4129,2611,0.03,0.09,1.58496250072116,0.529947764267329,"*",0.37379,"MAOB","GO:0016021//integral component of membrane","GO:0016491//oxidoreductase activity","NA","K00274//monoamine oxidase [EC:1.4.3.4]","XP_003808422.1//PREDICTED: amine oxidase [flavin-containing] B [Pan paniscus]",4]
[4684,5977,0.01,0.03,1.58496250072116,0.392653868060349,"*",0.249274,"NCAM1","GO:0016020//membrane;GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0009897//external side of plasma membrane;GO:0031225//anchored component of membrane;GO:0000139//Golgi membrane;GO:0009986//cell surface;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0042802//identical protein binding;GO:0001618//virus receptor activity","GO:0060333//interferon-gamma-mediated signaling pathway;GO:0000165//MAPK cascade;GO:0007155//cell adhesion;GO:0007411//axon guidance","K06491//neural cell adhesion molecule","NP_001070150.1//neural cell adhesion molecule 1 isoform 3 precursor [Homo sapiens];NP_001229536.1//neural cell adhesion molecule 1 isoform 5 precursor [Homo sapiens];NP_851996.2//neural cell adhesion molecule 1 isoform 2 precursor [Homo sapiens];BAD92680.1//Neural cell adhesion molecule 1, 120 kDa isoform precursor variant, partial [Homo sapiens];NP_000606.3//neural cell adhesion molecule 1 isoform 1 precursor [Homo sapiens]","6;4;1//3;3//A2MP1"]
[401387,2661,0.01,0.03,1.58496250072116,0.644789870419801,"*",0.499032,"LRRD1","GO:0016323//basolateral plasma membrane;GO:0005737//cytoplasm","NA","GO:0007165//signal transduction;GO:0045199//maintenance of epithelial cell apical/basal polarity","K05917//sterol 14-demethylase [EC:1.14.13.70];K19613//leucine-rich repeat protein SHOC2","NP_001155000.1//leucine-rich repeat and death domain-containing protein 1 [Homo sapiens]","1//3"]
[947,2621,0.01,0.03,1.58496250072116,0.644633443959243,"*",0.499032,"CD34","GO:0009897//external side of plasma membrane;GO:0016324//apical plasma membrane;GO:0005764//lysosome;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0009925//basal plasma membrane;GO:0045171//intercellular bridge;GO:0005887//integral component of plasma membrane;GO:0036053//glomerular endothelium fenestra;GO:0005886//plasma membrane","GO:0030246//carbohydrate binding;GO:0043199//sulfate binding;GO:0008134//transcription factor binding","GO:0008217//regulation of blood pressure;GO:0061042//vascular wound healing;GO:0071971//extracellular exosome assembly;GO:1900041//negative regulation of interleukin-2 secretion;GO:0038001//paracrine signaling;GO:0045766//positive regulation of angiogenesis;GO:0072011//glomerular endothelium development;GO:0072089//stem cell proliferation;GO:0035759//mesangial cell-matrix adhesion;GO:0001935//endothelial cell proliferation;GO:1900035//negative regulation of cellular response to heat;GO:0007165//signal transduction;GO:0042482//positive regulation of odontogenesis;GO:0045019//negative regulation of nitric oxide biosynthetic process;GO:0010628//positive regulation of gene expression;GO:0060290//transdifferentiation;GO:0007160//cell-matrix adhesion;GO:0072254//metanephric glomerular mesangial cell differentiation;GO:1901215//negative regulation of neuron death;GO:0032733//positive regulation of interleukin-10 production;GO:0003094//glomerular filtration;GO:0010629//negative regulation of gene expression;GO:0032720//negative regulation of tumor necrosis factor production;GO:1900168//positive regulation of glial cell-derived neurotrophic factor secretion;GO:0098609//cell-cell adhesion;GO:0071425//hematopoietic stem cell proliferation;GO:0008283//cell proliferation;GO:0048870//cell motility;GO:0071657//positive regulation of granulocyte colony-stimulating factor production;GO:0003158//endothelium development;GO:0030097//hemopoiesis;GO:0050776//regulation of immune response;GO:1900038//negative regulation of cellular response to hypoxia;GO:0030195//negative regulation of blood coagulation;GO:0050900//leukocyte migration;GO:2001214//positive regulation of vasculogenesis;GO:0001894//tissue homeostasis;GO:0071636//positive regulation of transforming growth factor beta production","K06474//CD34 antigen","NP_001020280.1//hematopoietic progenitor cell antigen CD34 isoform a precursor [Homo sapiens];NP_001764.1//hematopoietic progenitor cell antigen CD34 isoform b precursor [Homo sapiens]","1//3;2//1"]
[6326,8607,0.01,0.03,1.58496250072116,0.529853710178365,"*",0.37379,"SCN2A","GO:0030315//T-tubule;GO:0030424//axon;GO:0031226//intrinsic component of plasma membrane;GO:0034706//sodium channel complex;GO:0005622//intracellular;GO:0033270//paranode region of axon;GO:0005887//integral component of plasma membrane;GO:0001518//voltage-gated sodium channel complex;GO:0014704//intercalated disc;GO:0033268//node of Ranvier;GO:0005886//plasma membrane","GO:0005248//voltage-gated sodium channel activity","GO:0007399//nervous system development;GO:0042552//myelination;GO:0035725//sodium ion transmembrane transport;GO:0051402//neuron apoptotic process;GO:0008627//intrinsic apoptotic signaling pathway in response to osmotic stress;GO:0086010//membrane depolarization during action potential;GO:0019228//neuronal action potential;GO:0006814//sodium ion transport","K04834//voltage-gated sodium channel type II alpha","NP_001035233.1//sodium channel protein type 2 subunit alpha isoform 2 [Homo sapiens];NP_066287.2//sodium channel protein type 2 subunit alpha isoform 1 [Homo sapiens]","1//3;2//1"]
[9247,2379,0.01,0.03,1.58496250072116,0.644477093378608,"*",0.499032,"GCM2","GO:0005634//nucleus","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0043565//sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0060706//cell differentiation involved in embryonic placenta development;GO:0060017//parathyroid gland development;GO:0007275//multicellular organism development;GO:0042063//gliogenesis;GO:0030643//cellular phosphate ion homeostasis;GO:0006874//cellular calcium ion homeostasis;GO:0006366//transcription from RNA polymerase II promoter","K21598//chorion-specific transcription factor GCM","NP_004743.1//chorion-specific transcription factor GCMb [Homo sapiens]","3//A2MP1"]
[140766,5557,0.01,0.03,1.58496250072116,0.39246036625271,"*",0.249274,"ADAMTS14","NA","NA","NA","K08628//a disintegrin and metalloproteinase with thrombospondin motifs 14 [EC:3.4.24.-]","AAL40229.1//a disintegrin-like and metalloprotease with thrombospondin type 1 motif 14 precursor [Homo sapiens]","4;3//A2MP1"]
[442862,1238,0.01,0.03,1.58496250072116,0.999469979833406,"*",0.999032,"PRY2","NA","NA","NA","K07899//Ras-related protein Rab-9A","NP_004667.2//PTPN13-like protein, Y-linked [Homo sapiens]","1//3"]
[79843,2693,0.01,0.03,1.58496250072116,0.643644502866371,"*",0.499032,"FAM124B","GO:0005654//nucleoplasm;GO:0005739//mitochondrion","NA","NA","K09291//nucleoprotein TPR;K09491//stress 70 protein chaperone microsome-associated 60kDa protein","XP_011807312.1//PREDICTED: protein FAM124B isoform X2 [Colobus angolensis palliatus];NP_001116251.1//protein FAM124B isoform a [Homo sapiens]","1//3;2//1"]
[126410,2620,0.01,0.03,1.58496250072116,0.643177115378409,"*",0.499032,"CYP4F22","GO:0031090//organelle membrane;GO:0005789//endoplasmic reticulum membrane","GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0020037//heme binding;GO:0005506//iron ion binding;GO:0004497//monooxygenase activity","GO:0006690//icosanoid metabolic process","K17731//cytochrome P450 family 4 subfamily F polypeptide 22","NP_775754.2//cytochrome P450 4F22 [Homo sapiens]","3//A2MP1"]
[155,2660,0.01,0.03,1.58496250072116,0.643125225332795,"*",0.499032,"ADRB3","GO:0005634//nucleus;GO:0005887//integral component of plasma membrane;GO:0005622//intracellular;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0043235//receptor complex","GO:0051380//norepinephrine binding;GO:0031699//beta-3 adrenergic receptor binding;GO:0015052//beta3-adrenergic receptor activity;GO:0051379//epinephrine binding;GO:0004939//beta-adrenergic receptor activity;GO:0042803//protein homodimerization activity","GO:0001659//temperature homeostasis;GO:0031649//heat generation;GO:0046677//response to antibiotic;GO:0006112//energy reserve metabolic process;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0005975//carbohydrate metabolic process;GO:0040015//negative regulation of multicellular organism growth;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0002024//diet induced thermogenesis;GO:0009409//response to cold;GO:0042755//eating behavior;GO:0007267//cell-cell signaling;GO:0006091//generation of precursor metabolites and energy;GO:0007568//aging;GO:0071880//adenylate cyclase-activating adrenergic receptor signaling pathway;GO:0007190//activation of adenylate cyclase activity;GO:0050873//brown fat cell differentiation;GO:0043410//positive regulation of MAPK cascade;GO:0002025//norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger","K04143//adrenergic receptor beta-3","NP_000016.1//beta-3 adrenergic receptor [Homo sapiens]","2//1"]
[149647,2332,0.01,0.03,1.58496250072116,0.642917748850714,"*",0.499032,"FAM71A","GO:0005634//nucleus","NA","NA","K10772//AP endonuclease 2 [EC:4.2.99.18];K06568//mucin-1;K12374//arylsulfatase D/F/H [EC:3.1.6.-]","NP_705834.2//protein FAM71A [Homo sapiens]","3//A2MP1"]
[11255,2680,0.01,0.03,1.58496250072116,0.642814060801548,"*",0.499032,"HRH3","GO:0005887//integral component of plasma membrane;GO:0098793//presynapse;GO:0005886//plasma membrane","GO:0004969//histamine receptor activity","GO:0014050//negative regulation of glutamate secretion;GO:0050890//cognition;GO:0007269//neurotransmitter secretion;GO:0007194//negative regulation of adenylate cyclase activity;GO:0014061//regulation of norepinephrine secretion;GO:0014063//negative regulation of serotonin secretion;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger","K04151//histamine receptor H3","NP_009163.2//histamine H3 receptor [Homo sapiens]","2//1"]
[696,2859,0.01,0.03,1.58496250072116,0.64271040619205,"*",0.499032,"BTN1A1","GO:0005615//extracellular space;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004872//receptor activity","NA","K06712//butyrophilin","XP_005249397.2//PREDICTED: butyrophilin subfamily 1 member A1 isoform X1 [Homo sapiens]","2//1"]
[4283,2723,0.01,0.03,1.58496250072116,0.642554986941802,"*",0.499032,"CXCL9","GO:0005615//extracellular space;GO:0009897//external side of plasma membrane;GO:0005623//cell;GO:0005576//extracellular region","GO:0005125//cytokine activity;GO:0048248//CXCR3 chemokine receptor binding;GO:0008009//chemokine activity","GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0042127//regulation of cell proliferation;GO:0032496//response to lipopolysaccharide;GO:0030816//positive regulation of cAMP metabolic process;GO:0010818//T cell chemotaxis;GO:0006935//chemotaxis;GO:1901741//positive regulation of myoblast fusion;GO:0043950//positive regulation of cAMP-mediated signaling;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0070098//chemokine-mediated signaling pathway;GO:0051607//defense response to virus;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0031640//killing of cells of other organism;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0006968//cellular defense response;GO:0006954//inflammatory response;GO:0006952//defense response;GO:0006955//immune response;GO:0045663//positive regulation of myoblast differentiation","K05416//C-X-C motif chemokine 9","XP_007997133.1//PREDICTED: C-X-C motif chemokine 9 [Chlorocebus sabaeus]","2//1"]
[64063,1391,0.06,0.18,1.58496250072116,0.529571748115299,"*",0.37379,"PRSS22","GO:0005576//extracellular region;GO:0046658//anchored component of plasma membrane;GO:0019897//extrinsic component of plasma membrane","GO:0004252//serine-type endopeptidase activity;GO:0008236//serine-type peptidase activity","NA","K09626//brain-specific serine protease 4 [EC:3.4.21.-]","AAQ88762.1//PRSS22, partial [Homo sapiens]","3//A2MP1"]
[56097,4641,0.01,0.03,1.58496250072116,0.642296121827411,"*",0.499032,"PCDHGC5","GO:0070062//extracellular exosome;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005509//calcium ion binding","GO:0007399//nervous system development;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007267//cell-cell signaling;GO:0050808//synapse organization","K16497//protocadherin gamma subfamily C","NP_115783.1//protocadherin gamma-C5 isoform 2 precursor [Homo sapiens];NP_061752.1//protocadherin gamma-C5 isoform 1 precursor [Homo sapiens]","1//3;2//1"]
[64240,2740,0.01,0.03,1.58496250072116,0.642037465206186,"*",0.499032,"ABCG5","GO:0016324//apical plasma membrane;GO:0043190//ATP-binding cassette (ABC) transporter complex;GO:0005886//plasma membrane;GO:0043235//receptor complex","GO:0005524//ATP binding;GO:0046982//protein heterodimerization activity;GO:0042626//ATPase activity, coupled to transmembrane movement of substances;GO:0017127//cholesterol transporter activity;GO:0016887//ATPase activity","GO:0055085//transmembrane transport;GO:0010212//response to ionizing radiation;GO:0007588//excretion;GO:0033344//cholesterol efflux;GO:0045796//negative regulation of intestinal cholesterol absorption;GO:0030299//intestinal cholesterol absorption;GO:0007584//response to nutrient;GO:0042632//cholesterol homeostasis;GO:0010949//negative regulation of intestinal phytosterol absorption;GO:0006855//drug transmembrane transport","K05683//ATP-binding cassette, subfamily G (WHITE), member 5 (sterolin 1)","NP_071881.1//ATP-binding cassette sub-family G member 5 [Homo sapiens]","2//1"]
[339862,2344,0.01,0.03,1.58496250072116,0.641985758878956,"*",0.499032,"LOC339862","NA","NA","NA","NA","NP_001244106.1//uncharacterized protein LOC339862 [Homo sapiens]","1//3"]
[219681,2529,0.01,0.03,1.58496250072116,0.641882371205411,"*",0.499032,"ARMC3","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005737//cytoplasm","NA","NA","K12642//plakophilin 2;K08332//vacuolar protein 8","EAW86138.1//armadillo repeat containing 3, isoform CRA_b [Homo sapiens];NP_775104.2//armadillo repeat-containing protein 3 isoform 1 [Homo sapiens];NP_001269675.1//armadillo repeat-containing protein 3 isoform 3 [Homo sapiens];NP_001269674.1//armadillo repeat-containing protein 3 isoform 2 [Homo sapiens]","4;1//3"]
[1441,3419,0.01,0.03,1.58496250072116,0.64162404764971,"*",0.499032,"CSF3R","GO:0005887//integral component of plasma membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0004872//receptor activity;GO:0051916//granulocyte colony-stimulating factor binding;GO:0004896//cytokine receptor activity","GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0030593//neutrophil chemotaxis;GO:0006952//defense response;GO:0045637//regulation of myeloid cell differentiation;GO:0097186//amelogenesis","K05061//granulocyte colony-stimulating factor receptor","NP_000751.1//granulocyte colony-stimulating factor receptor isoform a precursor [Homo sapiens];NP_724781.1//granulocyte colony-stimulating factor receptor isoform c precursor [Homo sapiens];NP_758519.1//granulocyte colony-stimulating factor receptor isoform d precursor [Homo sapiens]","3//A2MP1;2//1"]
[401447,1593,0.01,0.03,1.58496250072116,0.999344803556891,"*",0.999032,"USP17L1","GO:0005783//endoplasmic reticulum;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005789//endoplasmic reticulum membrane","GO:0004843//thiol-dependent ubiquitin-specific protease activity;GO:0036459//thiol-dependent ubiquitinyl hydrolase activity","GO:0071108//protein K48-linked deubiquitination;GO:0042127//regulation of cell proliferation;GO:0043547//positive regulation of GTPase activity;GO:0071586//CAAX-box protein processing;GO:0010955//negative regulation of protein processing;GO:1900245//positive regulation of MDA-5 signaling pathway;GO:0006511//ubiquitin-dependent protein catabolic process;GO:1900027//regulation of ruffle assembly;GO:0030334//regulation of cell migration;GO:0016579//protein deubiquitination;GO:0031064//negative regulation of histone deacetylation;GO:0070536//protein K63-linked deubiquitination;GO:0090315//negative regulation of protein targeting to membrane;GO:0006915//apoptotic process;GO:0007093//mitotic cell cycle checkpoint;GO:1900246//positive regulation of RIG-I signaling pathway;GO:0034260//negative regulation of GTPase activity;GO:0050691//regulation of defense response to virus by host;GO:0042981//regulation of apoptotic process","K11845//ubiquitin carboxyl-terminal hydrolase 17 [EC:3.4.19.12]","NP_001243800.1//ubiquitin carboxyl-terminal hydrolase 17-like protein 3 [Homo sapiens]","1//3"]
[645836,1593,0.01,0.03,1.58496250072116,0.999219658631269,"*",0.999032,"USP17L3","GO:0005634//nucleus;GO:0005783//endoplasmic reticulum","GO:0036459//thiol-dependent ubiquitinyl hydrolase activity","GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination;GO:0006915//apoptotic process","K11845//ubiquitin carboxyl-terminal hydrolase 17 [EC:3.4.19.12]","NP_001243800.1//ubiquitin carboxyl-terminal hydrolase 17-like protein 3 [Homo sapiens]","1//3"]
[10840,3204,0.01,0.03,1.58496250072116,0.641108023805694,"*",0.499032,"ALDH1L1","NA","GO:0016742//hydroxymethyl-, formyl- and related transferase activity;GO:0016491//oxidoreductase activity","GO:0009058//biosynthetic process","K00289//formyltetrahydrofolate dehydrogenase [EC:1.5.1.6]","XP_011924019.1//PREDICTED: cytosolic 10-formyltetrahydrofolate dehydrogenase isoform X2 [Cercocebus atys];XP_011826910.1//PREDICTED: cytosolic 10-formyltetrahydrofolate dehydrogenase isoform X2 [Mandrillus leucophaeus];XP_010378871.1//PREDICTED: cytosolic 10-formyltetrahydrofolate dehydrogenase isoform X3 [Rhinopithecus roxellana]","1//3;3//A2MP1"]
[338809,2369,0.01,0.03,1.58496250072116,0.641056467068758,"*",0.499032,"C12orf74","NA","NA","NA","NA","EAW97470.1//hypothetical protein LOC338809, partial [Homo sapiens]","3//A2MP1;2//1"]
[6247,3040,0.01,0.03,1.58496250072116,0.640747300699301,"*",0.499032,"RS1","GO:0005615//extracellular space;GO:0019897//extrinsic component of plasma membrane","GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0010314//phosphatidylinositol-5-phosphate binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0070492//oligosaccharide binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0080025//phosphatidylinositol-3,5-bisphosphate binding;GO:0070273//phosphatidylinositol-4-phosphate binding;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding;GO:0001786//phosphatidylserine binding","GO:0016062//adaptation of rhodopsin mediated signaling;GO:0007155//cell adhesion;GO:0007275//multicellular organism development;GO:0007601//visual perception;GO:0051260//protein homooligomerization;GO:0010842//retina layer formation","K16669//protocadherin Fat 4;K03902//coagulation factor V (labile factor)","NP_000321.1//retinoschisin precursor [Homo sapiens]","3//A2MP1"]
[4322,2735,0.03,0.09,1.58496250072116,0.529337008865248,"*",0.37379,"MMP13","GO:0031012//extracellular matrix;GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix","GO:0004252//serine-type endopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0005518//collagen binding;GO:0005509//calcium ion binding;GO:0008270//zinc ion binding","GO:0022617//extracellular matrix disassembly;GO:0001958//endochondral ossification;GO:0044267//cellular protein metabolic process;GO:0030282//bone mineralization;GO:0006508//proteolysis;GO:0003417//growth plate cartilage development;GO:0060349//bone morphogenesis;GO:0030574//collagen catabolic process","K07994//matrix metalloproteinase-13 (collagenase 3) [EC:3.4.24.-]","NP_002418.1//collagenase 3 preproprotein [Homo sapiens]","3//A2MP1"]
[56111,4778,0.01,0.03,1.58496250072116,0.640386983290488,"*",0.499032,"PCDHGA4","NA","NA","NA","K16495//protocadherin gamma subfamily A","XP_010592269.1//PREDICTED: LOW QUALITY PROTEIN: protocadherin gamma-A4-like [Loxodonta africana]","3//A2MP1;2//1"]
[945,1108,0.04,0.12,1.58496250072116,0.640181269514937,"*",0.499032,"CD33","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0009897//external side of plasma membrane;GO:0005887//integral component of plasma membrane;GO:0035579//specific granule membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0070821//tertiary granule membrane","GO:0030246//carbohydrate binding;GO:0004872//receptor activity","GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0043312//neutrophil degranulation;GO:0007267//cell-cell signaling;GO:0050776//regulation of immune response;GO:0008285//negative regulation of cell proliferation","K06473//CD33 antigen","XP_011525833.1//PREDICTED: myeloid cell surface antigen CD33 isoform X1 [Homo sapiens];XP_016882999.1//PREDICTED: myeloid cell surface antigen CD33 isoform X4 [Homo sapiens]","1//3;3//A2MP1"]
[816,4097,0.02,0.06,1.58496250072116,0.529290085985285,"*",0.37379,"CAMK2B","GO:0005654//nucleoplasm;GO:0005815//microtubule organizing center;GO:0030666//endocytic vesicle membrane;GO:0005737//cytoplasm;GO:0043005//neuron projection;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0033017//sarcoplasmic reticulum membrane","GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0003779//actin binding;GO:0004674//protein serine/threonine kinase activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0004672//protein kinase activity;GO:0004683//calmodulin-dependent protein kinase activity;GO:0005516//calmodulin binding","GO:0014733//regulation of skeletal muscle adaptation;GO:0060998//regulation of dendritic spine development;GO:0035556//intracellular signal transduction;GO:0051823//regulation of synapse structural plasticity;GO:0051924//regulation of calcium ion transport;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0000165//MAPK cascade;GO:0007165//signal transduction;GO:0006468//protein phosphorylation;GO:0010976//positive regulation of neuron projection development;GO:0046777//protein autophosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:1900034//regulation of cellular response to heat;GO:0018105//peptidyl-serine phosphorylation;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0061003//positive regulation of dendritic spine morphogenesis;GO:0090129//positive regulation of synapse maturation","K04515//calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]","NP_742080.1//calcium/calmodulin-dependent protein kinase type II subunit beta isoform 7 [Homo sapiens];NP_001211.3//calcium/calmodulin-dependent protein kinase type II subunit beta isoform 1 [Homo sapiens];NP_742076.1//calcium/calmodulin-dependent protein kinase type II subunit beta isoform 3 [Homo sapiens];NP_742078.1//calcium/calmodulin-dependent protein kinase type II subunit beta isoform 5 [Homo sapiens];NP_742081.1//calcium/calmodulin-dependent protein kinase type II subunit beta isoform 8 [Homo sapiens];NP_742077.1//calcium/calmodulin-dependent protein kinase type II subunit beta isoform 4 [Homo sapiens];NP_742075.1//calcium/calmodulin-dependent protein kinase type II subunit beta isoform 2 [Homo sapiens];NP_742079.1//calcium/calmodulin-dependent protein kinase type II subunit beta isoform 6 [Homo sapiens]","1//3;4;2//1"]
[140706,2532,0.01,0.03,1.58496250072116,0.639411018528916,"*",0.499032,"CCM2L","NA","NA","GO:0003222//ventricular trabecula myocardium morphogenesis;GO:0034111//negative regulation of homotypic cell-cell adhesion;GO:0003209//cardiac atrium morphogenesis;GO:0090271//positive regulation of fibroblast growth factor production;GO:0032091//negative regulation of protein binding;GO:0042060//wound healing;GO:0055017//cardiac muscle tissue growth","K19475//WAS/WASL-interacting protein;K05747//Wiskott-Aldrich syndrome protein;K05748//WAS protein family, member 2","NP_542192.2//cerebral cavernous malformations 2 protein-like [Homo sapiens]","3//A2MP1"]
[25891,2818,0.01,0.03,1.58496250072116,0.639257190697674,"*",0.499032,"PAMR1","GO:0005615//extracellular space","GO:0004252//serine-type endopeptidase activity;GO:0005509//calcium ion binding","NA","K17495//CUB and sushi domain-containing protein;K05502//bone morphogenetic protein 1 [EC:3.4.24.19]","NP_001001991.1//inactive serine protease PAMR1 isoform b precursor [Homo sapiens];EAW68140.1//regeneration associated muscle protease [Homo sapiens];NP_001269605.1//inactive serine protease PAMR1 isoform d precursor [Homo sapiens]","1//3;3//A2MP1;2//1"]
[170680,1185,0.07,0.21,1.58496250072116,0.531173513032648,"*",0.37379,"PSORS1C2","GO:0005576//extracellular region","NA","NA","K16760//coiled-coil alpha-helical rod protein 1;K10572//inositol-pentakisphosphate 2-kinase [EC:2.7.1.158];K07604//type I keratin, acidic","XP_005553644.1//PREDICTED: psoriasis susceptibility 1 candidate gene 2 protein [Macaca fascicularis]","2//1"]
[387715,833,0.1,0.3,1.58496250072116,0.530795756067206,"*",0.37379,"ARMS2","GO:0001917//photoreceptor inner segment;GO:0005739//mitochondrion","NA","GO:0001895//retina homeostasis","NA","NP_001093137.1//age-related maculopathy susceptibility protein 2 [Homo sapiens]","2//1"]
[3861,1653,0.05,0.15,1.58496250072116,0.530748574222222,"*",0.37379,"KRT14","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005829//cytosol;GO:0071944//cell periphery;GO:0045095//keratin filament;GO:0005882//intermediate filament;GO:0005737//cytoplasm;GO:0045178//basal part of cell","GO:1990254//keratin filament binding;GO:0005200//structural constituent of cytoskeleton","GO:0045110//intermediate filament bundle assembly;GO:0010212//response to ionizing radiation;GO:0010043//response to zinc ion;GO:0031424//keratinization;GO:0031581//hemidesmosome assembly;GO:0070268//cornification;GO:0007568//aging;GO:0008544//epidermis development;GO:0042633//hair cycle","K07604//type I keratin, acidic","XP_003279474.2//PREDICTED: keratin, type I cytoskeletal 14 [Nomascus leucogenys]",4]
[284451,1607,0.05,0.15,1.58496250072116,0.530701400764377,"*",0.37379,"ODF3L2","GO:0005881//cytoplasmic microtubule","NA","NA","K19719//collagen, type II, alpha;K19475//WAS/WASL-interacting protein;K21125//mucin-5AC","NP_872383.1//outer dense fiber protein 3-like protein 2 [Homo sapiens]","2//1"]
[3483,2168,0.07,0.21,1.58496250072116,0.303802091806767,"*",0.1787362,"IGFALS","GO:0070062//extracellular exosome;GO:0005654//nucleoplasm;GO:0042567//insulin-like growth factor ternary complex;GO:0005615//extracellular space;GO:0005576//extracellular region","GO:0005520//insulin-like growth factor binding","GO:0044267//cellular protein metabolic process;GO:0007155//cell adhesion;GO:0007165//signal transduction","K17256//insulin-like growth factor-binding protein complex acid labile subunit","NP_004961.1//insulin-like growth factor-binding protein complex acid labile subunit isoform 2 precursor [Homo sapiens];NP_001139478.1//insulin-like growth factor-binding protein complex acid labile subunit isoform 1 precursor [Homo sapiens]","1//3;2//1"]
[57393,1580,0.05,0.15,1.58496250072116,0.529477827436375,"*",0.37379,"CLTRN","GO:0070062//extracellular exosome;GO:0031526//brush border membrane;GO:0016021//integral component of membrane;GO:0005737//cytoplasm","GO:0008241//peptidyl-dipeptidase activity;GO:0008237//metallopeptidase activity","GO:0051957//positive regulation of amino acid transport;GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0045956//positive regulation of calcium ion-dependent exocytosis;GO:0035543//positive regulation of SNARE complex assembly","K20004//collectrin","XP_016798474.1//PREDICTED: collectrin [Pan troglodytes]",5]
[3592,1329,1.28,3.82,1.57742882803575,{"v":7.12957361350099e-06,"d":"7.13E-06"},"Up",{"v":1.34879E-6,"d":"1.35E-06"},"IL12A","GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0043514//interleukin-12 complex;GO:0005576//extracellular region;GO:0031906//late endosome lumen;GO:0005737//cytoplasm","GO:0008083//growth factor activity;GO:0005125//cytokine activity;GO:0042163//interleukin-12 beta subunit binding;GO:0046982//protein heterodimerization activity;GO:0045513//interleukin-27 binding;GO:0005143//interleukin-12 receptor binding","GO:0016477//cell migration;GO:0097191//extrinsic apoptotic signaling pathway;GO:0042102//positive regulation of T cell proliferation;GO:0051135//positive regulation of NK T cell activation;GO:0045785//positive regulation of cell adhesion;GO:0071222//cellular response to lipopolysaccharide;GO:0032496//response to lipopolysaccharide;GO:0007050//cell cycle arrest;GO:0035744//T-helper 1 cell cytokine production;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0032816//positive regulation of natural killer cell activation;GO:0008283//cell proliferation;GO:0045582//positive regulation of T cell differentiation;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0050830//defense response to Gram-positive bacterium;GO:0032729//positive regulation of interferon-gamma production;GO:0035722//interleukin-12-mediated signaling pathway;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0002860//positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target;GO:0042832//defense response to protozoan;GO:2000510//positive regulation of dendritic cell chemotaxis;GO:0050671//positive regulation of lymphocyte proliferation;GO:0032946//positive regulation of mononuclear cell proliferation;GO:0010224//response to UV-B;GO:0034393//positive regulation of smooth muscle cell apoptotic process;GO:0032609//interferon-gamma production;GO:0032700//negative regulation of interleukin-17 production;GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0006955//immune response;GO:0098586//cellular response to virus;GO:0009615//response to virus","K05406//interleukin 12A","NP_001341512.1//interleukin-12 subunit alpha isoform 3 [Homo sapiens];XP_008981813.2//PREDICTED: interleukin-12 subunit alpha [Callithrix jacchus]","1//3;3//A2MP1"]
[23586,4759,1.3,3.86,1.57008922423963,{"v":5.07808630235162e-18,"d":"5.08E-18"},"Up",{"v":2.83882e-19,"d":"2.84E-19"},"DDX58","GO:0005829//cytosol;GO:0005923//bicellular tight junction;GO:0015629//actin cytoskeleton;GO:0032587//ruffle membrane;GO:0005737//cytoplasm","GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0004386//helicase activity;GO:0003725//double-stranded RNA binding;GO:0003690//double-stranded DNA binding;GO:0008270//zinc ion binding;GO:0003727//single-stranded RNA binding","GO:0032755//positive regulation of interleukin-6 production;GO:0060760//positive regulation of response to cytokine stimulus;GO:0030334//regulation of cell migration;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0035549//positive regulation of interferon-beta secretion;GO:0016579//protein deubiquitination;GO:0045087//innate immune response;GO:2000778//positive regulation of interleukin-6 secretion;GO:0039528//cytoplasmic pattern recognition receptor signaling pathway in response to virus;GO:0032728//positive regulation of interferon-beta production;GO:0009597//detection of virus;GO:0071360//cellular response to exogenous dsRNA;GO:0051607//defense response to virus;GO:0032727//positive regulation of interferon-alpha production;GO:0032757//positive regulation of interleukin-8 production;GO:0016032//viral process;GO:0034344//regulation of type III interferon production;GO:0010628//positive regulation of gene expression;GO:1904469//positive regulation of tumor necrosis factor secretion;GO:0032725//positive regulation of granulocyte macrophage colony-stimulating factor production;GO:0039529//RIG-I signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:1902741//positive regulation of interferon-alpha secretion;GO:0032480//negative regulation of type I interferon production;GO:0009615//response to virus;GO:0002230//positive regulation of defense response to virus by host;GO:0042993//positive regulation of transcription factor import into nucleus","K12646//ATP-dependent RNA helicase DDX58 [EC:3.6.3.14]","NP_055129.2//probable ATP-dependent RNA helicase DDX58 [Homo sapiens]","3//A2MP1"]
[121504,412,0.22,0.65,1.56293619439116,0.530324314770406,"*",0.37379,"HIST4H4","NA","NA","NA","K11254//histone H4","XP_009423180.2//PREDICTED: histone H4 [Pan troglodytes]","2//1"]
[2258,2450,0.2,0.59,1.56071495447448,0.0356574052867522,"*",0.0144402,"FGF13","GO:0030425//dendrite;GO:0030424//axon;GO:0005634//nucleus;GO:0005874//microtubule;GO:0005737//cytoplasm;GO:0043005//neuron projection;GO:0030175//filopodium;GO:0030426//growth cone;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005576//extracellular region;GO:0014704//intercalated disc;GO:0016328//lateral plasma membrane;GO:0005886//plasma membrane","GO:0044325//ion channel binding;GO:0008083//growth factor activity;GO:0048487//beta-tubulin binding;GO:0017080//sodium channel regulator activity;GO:0030295//protein kinase activator activity;GO:0008017//microtubule binding","GO:0007399//nervous system development;GO:0021766//hippocampus development;GO:1990834//response to odorant;GO:0021795//cerebral cortex cell migration;GO:0007026//negative regulation of microtubule depolymerization;GO:0006814//sodium ion transport;GO:0048671//negative regulation of collateral sprouting;GO:0000165//MAPK cascade;GO:0072659//protein localization to plasma membrane;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0098909//regulation of cardiac muscle cell action potential involved in regulation of contraction;GO:0045200//establishment of neuroblast polarity;GO:0007612//learning;GO:0007613//memory;GO:0001764//neuron migration;GO:0046785//microtubule polymerization","K04358//fibroblast growth factor","NP_001132970.1//fibroblast growth factor 13 isoform 4 [Homo sapiens];NP_001132972.1//fibroblast growth factor 13 isoform 2 [Homo sapiens];NP_378668.1//fibroblast growth factor 13 isoform 5 [Homo sapiens];NP_004105.1//fibroblast growth factor 13 isoform 1 [Homo sapiens];XP_011811213.1//PREDICTED: fibroblast growth factor 13 isoform X2 [Colobus angolensis palliatus]","1//3;3//A2MP1;2//1"]
[54659,2345,0.17,0.5,1.55639334852439,0.0454280472934132,"*",0.01899708,"UGT1A3","GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0046982//protein heterodimerization activity;GO:0015020//glucuronosyltransferase activity;GO:0001972//retinoic acid binding;GO:0042803//protein homodimerization activity;GO:0019899//enzyme binding","GO:2001030//negative regulation of cellular glucuronidation;GO:0008152//metabolic process;GO:0052697//xenobiotic glucuronidation;GO:0042573//retinoic acid metabolic process;GO:0052695//cellular glucuronidation;GO:0045922//negative regulation of fatty acid metabolic process;GO:1904224//negative regulation of glucuronosyltransferase activity;GO:0052696//flavonoid glucuronidation","K00699//glucuronosyltransferase [EC:2.4.1.17]","NP_061966.1//UDP-glucuronosyltransferase 1-3 precursor [Homo sapiens]","2//1"]
[3039,627,0.14,0.41,1.55019708256048,0.529994803834546,"*",0.37379,"HBA1","GO:0005833//hemoglobin complex","GO:0020037//heme binding;GO:0005506//iron ion binding;GO:0005344//oxygen carrier activity;GO:0019825//oxygen binding","NA","K13822//hemoglobin subunit alpha","SAI82135.1//TPA: globin C1 [Homo sapiens]",4]
[154,2058,0.31,0.9,1.5376567859428,0.0185310238571669,"*",0.00688736,"ADRB2","GO:0016020//membrane;GO:0010008//endosome membrane;GO:0005634//nucleus;GO:0016324//apical plasma membrane;GO:0005764//lysosome;GO:0043235//receptor complex;GO:0005768//endosome;GO:0005887//integral component of plasma membrane;GO:0030665//clathrin-coated vesicle membrane;GO:0005886//plasma membrane;GO:0005769//early endosome","GO:0001540//amyloid-beta binding;GO:0015459//potassium channel regulator activity;GO:0051379//epinephrine binding;GO:0042803//protein homodimerization activity;GO:0008179//adenylate cyclase binding;GO:0051380//norepinephrine binding;GO:0004941//beta2-adrenergic receptor activity;GO:0032403//protein complex binding","GO:0031649//heat generation;GO:0007171//activation of transmembrane receptor protein tyrosine kinase activity;GO:0002028//regulation of sodium ion transport;GO:0007166//cell surface receptor signaling pathway;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0016579//protein deubiquitination;GO:0071875//adrenergic receptor signaling pathway;GO:0040015//negative regulation of multicellular organism growth;GO:0002024//diet induced thermogenesis;GO:0010739//positive regulation of protein kinase A signaling;GO:1990911//response to psychosocial stress;GO:2000969//positive regulation of AMPA receptor activity;GO:0071880//adenylate cyclase-activating adrenergic receptor signaling pathway;GO:1901098//positive regulation of autophagosome maturation;GO:0006898//receptor-mediated endocytosis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0050873//brown fat cell differentiation;GO:2000481//positive regulation of cAMP-dependent protein kinase activity;GO:0002025//norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure;GO:0045986//negative regulation of smooth muscle contraction;GO:0061885//positive regulation of mini excitatory postsynaptic potential;GO:0002032//desensitization of G-protein coupled receptor protein signaling pathway by arrestin;GO:0008333//endosome to lysosome transport;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0045453//bone resorption;GO:1904504//positive regulation of lipophagy;GO:0009409//response to cold;GO:0007267//cell-cell signaling;GO:0031398//positive regulation of protein ubiquitination;GO:1904646//cellular response to amyloid-beta;GO:0061024//membrane organization;GO:0007190//activation of adenylate cyclase activity;GO:0030501//positive regulation of bone mineralization;GO:0043410//positive regulation of MAPK cascade","K04142//adrenergic receptor beta-2","BAD96745.1//Adrenergic, beta-2-, receptor, surface variant, partial [Homo sapiens]",5]
[7074,5594,0.1,0.29,1.53605290024021,0.0662016338373752,"*",0.0290518,"TIAM1","GO:0005634//nucleus;GO:0044295//axonal growth cone;GO:0005874//microtubule;GO:0044304//main axon;GO:0044291//cell-cell contact zone;GO:0032587//ruffle membrane;GO:0014069//postsynaptic density;GO:0043025//neuronal cell body;GO:0005911//cell-cell junction;GO:0005829//cytosol;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0043197//dendritic spine;GO:0005886//plasma membrane","GO:0008289//lipid binding;GO:0005057//signal transducer activity, downstream of receptor;GO:0030971//receptor tyrosine kinase binding;GO:0030676//Rac guanyl-nucleotide exchange factor activity;GO:0019900//kinase binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0008017//microtubule binding;GO:0005089//Rho guanyl-nucleotide exchange factor activity","GO:0016477//cell migration;GO:0030335//positive regulation of cell migration;GO:0010717//regulation of epithelial to mesenchymal transition;GO:1904338//regulation of dopaminergic neuron differentiation;GO:0072657//protein localization to membrane;GO:0032092//positive regulation of protein binding;GO:0098989//NMDA selective glutamate receptor signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:1990138//neuron projection extension;GO:2000050//regulation of non-canonical Wnt signaling pathway;GO:0061178//regulation of insulin secretion involved in cellular response to glucose stimulus;GO:1905274//regulation of modification of postsynaptic actin cytoskeleton;GO:0090630//activation of GTPase activity;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0048013//ephrin receptor signaling pathway;GO:0050772//positive regulation of axonogenesis;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:1904268//positive regulation of Schwann cell chemotaxis;GO:0043507//positive regulation of JUN kinase activity;GO:0006915//apoptotic process;GO:0003300//cardiac muscle hypertrophy;GO:0016601//Rac protein signal transduction;GO:0007160//cell-matrix adhesion;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0035023//regulation of Rho protein signal transduction;GO:0042220//response to cocaine;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0061003//positive regulation of dendritic spine morphogenesis;GO:0008284//positive regulation of cell proliferation","K05731//T-lymphoma invasion and metastasis-inducing protein 1","NP_003244.2//T-lymphoma invasion and metastasis-inducing protein 1 isoform 1 [Homo sapiens];NP_001340616.1//T-lymphoma invasion and metastasis-inducing protein 1 isoform 4 [Homo sapiens];NP_001340614.1//T-lymphoma invasion and metastasis-inducing protein 1 isoform 3 [Homo sapiens];NP_001340615.1//T-lymphoma invasion and metastasis-inducing protein 1 isoform 4 [Homo sapiens];XP_006155328.1//PREDICTED: T-lymphoma invasion and metastasis-inducing protein 1 isoform X2 [Tupaia chinensis]","1//3;3//A2MP1"]
[127670,2500,0.09,0.26,1.53051471669878,0.131590028151154,"*",0.064963,"TEDDM1","NA","NA","NA","K22069//LYR motif-containing protein 4;K12581//CCR4-NOT transcription complex subunit 7/8;K08857//NIMA (never in mitosis gene a)-related kinase 1/4/5 [EC:2.7.11.1];K06588//integrin beta 5;K01064//wingless-type MMTV integration site family, member 9","XP_003775525.1//PREDICTED: transmembrane epididymal protein 1 [Pongo abelii]","3//A2MP1"]
[118663,1877,0.09,0.26,1.53051471669878,0.303899101522086,"*",0.1787362,"BTBD16","GO:0005634//nucleus;GO:0000151//ubiquitin ligase complex","NA","NA","K10487//BTB/POZ domain-containing protein 16","NP_001305118.1//BTB/POZ domain-containing protein 16 isoform a [Homo sapiens];NP_653188.2//BTB/POZ domain-containing protein 16 isoform b [Homo sapiens]","1//3;3//A2MP1"]
[50617,3049,0.08,0.23,1.52356195605701,0.175888715625,"*",0.091611,"ATP6V0A4","GO:0005765//lysosomal membrane;GO:0070062//extracellular exosome;GO:0010008//endosome membrane;GO:0000220//vacuolar proton-transporting V-type ATPase, V0 domain;GO:0005903//brush border;GO:0016324//apical plasma membrane;GO:0031526//brush border membrane;GO:0030670//phagocytic vesicle membrane;GO:0005768//endosome;GO:0016021//integral component of membrane;GO:0045177//apical part of cell;GO:0016471//vacuolar proton-transporting V-type ATPase complex;GO:0005886//plasma membrane","GO:0015078//hydrogen ion transmembrane transporter activity;GO:0051117//ATPase binding;GO:0046961//proton-transporting ATPase activity, rotational mechanism","GO:0008286//insulin receptor signaling pathway;GO:0034220//ion transmembrane transport;GO:0006885//regulation of pH;GO:0007588//excretion;GO:0070072//vacuolar proton-transporting V-type ATPase complex assembly;GO:0090383//phagosome acidification;GO:0007035//vacuolar acidification;GO:0001503//ossification;GO:0015986//ATP synthesis coupled proton transport;GO:0015991//ATP hydrolysis coupled proton transport;GO:0007605//sensory perception of sound;GO:0033572//transferrin transport;GO:0015992//proton transport","K02154//V-type H+-transporting ATPase subunit a","NP_065683.2//V-type proton ATPase 116 kDa subunit a isoform 4 [Homo sapiens]","2//1"]
[9478,1196,0.08,0.23,1.52356195605701,0.355921044901299,"*",0.217844,"CABP1","GO:0005856//cytoskeleton;GO:0005615//extracellular space;GO:0005938//cell cortex;GO:0030054//cell junction;GO:0014069//postsynaptic density;GO:0048471//perinuclear region of cytoplasm;GO:0000139//Golgi membrane;GO:0005886//plasma membrane;GO:0045211//postsynaptic membrane","GO:0005509//calcium ion binding;GO:0004857//enzyme inhibitor activity;GO:0048306//calcium-dependent protein binding;GO:0008139//nuclear localization sequence binding","GO:0042308//negative regulation of protein import into nucleus","K02183//calmodulin","NP_001028849.1//calcium-binding protein 1 isoform 3 [Homo sapiens];XP_014956896.1//PREDICTED: calcium-binding protein 1 isoform X1 [Ovis aries];EDL19873.1//calcium binding protein 1, isoform CRA_a, partial [Mus musculus]","4;1//3;3//A2MP1"]
[8638,2093,0.28,0.8,1.51457317282976,0.0159946116129032,"*",0.00583552,"OASL","GO:0016020//membrane;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0003677//DNA binding;GO:0046966//thyroid hormone receptor binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0003725//double-stranded RNA binding","GO:0060333//interferon-gamma-mediated signaling pathway;GO:0060337//type I interferon signaling pathway;GO:0045071//negative regulation of viral genome replication;GO:0006955//immune response;GO:0051607//defense response to virus;GO:0009615//response to virus","K14608//2'-5'-oligoadenylate synthase-like protein","NP_003724.1//2'-5'-oligoadenylate synthase-like protein isoform a [Homo sapiens];NP_937856.1//2'-5'-oligoadenylate synthase-like protein isoform b [Homo sapiens];NP_001248754.1//2'-5'-oligoadenylate synthase-like protein isoform c [Homo sapiens]","1//3;3//A2MP1;2//1"]
[138715,1239,0.07,0.2,1.51457317282976,0.530512790759662,"*",0.37379,"ARID3C","GO:0005634//nucleus;GO:0045121//membrane raft;GO:0005737//cytoplasm","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003682//chromatin binding","NA","K11653//AT-rich interactive domain-containing protein 1;K20719//sigma non-opioid intracellular receptor","XP_016869772.1//PREDICTED: AT-rich interactive domain-containing protein 3C isoform X1 [Homo sapiens]","1//3"]
[49861,1209,0.07,0.2,1.51457317282976,0.529383940065609,"*",0.37379,"CLDN20","GO:0016021//integral component of membrane;GO:0005923//bicellular tight junction;GO:0005886//plasma membrane","GO:0042802//identical protein binding;GO:0005198//structural molecule activity","GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules","K06087//claudin","NP_001001346.1//claudin-20 precursor [Homo sapiens]","3//A2MP1"]
[6773,4573,6.41,18.27,1.51108037200875,{"v":8.74745848421053e-75,"d":"8.75E-75"},"Up",{"v":7.28316e-77,"d":"7.28E-77"},"STAT2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0003677//DNA binding;GO:0042802//identical protein binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0004871//signal transducer activity;GO:0003700//DNA binding transcription factor activity","GO:0060337//type I interferon signaling pathway;GO:0007259//JAK-STAT cascade;GO:0051607//defense response to virus;GO:0006351//transcription, DNA-templated;GO:0016032//viral process;GO:0001932//regulation of protein phosphorylation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0060338//regulation of type I interferon-mediated signaling pathway;GO:0090140//regulation of mitochondrial fission","K11221//signal transducer and activator of transcription 2","NP_938146.1//signal transducer and activator of transcription 2 isoform 2 [Homo sapiens];NP_005410.1//signal transducer and activator of transcription 2 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[4160,1438,0.06,0.17,1.50250034052918,0.530418536022031,"*",0.37379,"MC4R","GO:0005634//nucleus;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0031625//ubiquitin protein ligase binding;GO:0017046//peptide hormone binding;GO:0042923//neuropeptide binding;GO:0004977//melanocortin receptor activity;GO:0004980//melanocyte-stimulating hormone receptor activity","GO:2000821//regulation of grooming behavior;GO:2000252//negative regulation of feeding behavior;GO:0002024//diet induced thermogenesis;GO:0032868//response to insulin;GO:0030073//insulin secretion;GO:0045780//positive regulation of bone resorption;GO:0006112//energy reserve metabolic process;GO:0007631//feeding behavior;GO:0030819//positive regulation of cAMP biosynthetic process;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway","K04202//melanocortin 4 receptor","NP_005903.2//melanocortin receptor 4 [Homo sapiens]","2//1"]
[30014,418,0.3,0.85,1.50250034052918,0.355702755392007,"*",0.217844,"SPANXA1","GO:0005634//nucleus;GO:0005737//cytoplasm","NA","GO:0007283//spermatogenesis","NA","NP_038481.2//sperm protein associated with the nucleus on the X chromosome A [Homo sapiens]","3//A2MP1"]
[9985,2354,1.39,3.91,1.49208372458384,{"v":6.67934701821862e-09,"d":"6.68E-09"},"Up",{"v":8.26242e-10,"d":"8.26E-10"},"REC8","GO:0000228//nuclear chromosome;GO:0005634//nucleus;GO:0001673//male germ cell nucleus;GO:0030893//meiotic cohesin complex;GO:0000778//condensed nuclear chromosome kinetochore;GO:0000798//nuclear cohesin complex;GO:0000800//lateral element;GO:0034991//nuclear meiotic cohesin complex","GO:0003682//chromatin binding","GO:0007141//male meiosis I;GO:0009566//fertilization;GO:0007286//spermatid development;GO:0001556//oocyte maturation;GO:0007283//spermatogenesis;GO:0007130//synaptonemal complex assembly;GO:0006302//double-strand break repair;GO:0007131//reciprocal meiotic recombination;GO:0051321//meiotic cell cycle;GO:0007062//sister chromatid cohesion;GO:0072520//seminiferous tubule development;GO:0000724//double-strand break repair via homologous recombination","K13054//meiotic recombination protein REC8, animal type","NP_005123.2//meiotic recombination protein REC8 homolog [Homo sapiens]","1//3;2//1"]
[164781,1953,0.16,0.45,1.49185309632967,0.150139830997039,"*",0.0761696,"DAW1","GO:0005929//cilium;GO:0005737//cytoplasm","NA","GO:0007368//determination of left/right symmetry;GO:0007507//heart development","K19760//dynein assembly factor with WDR repeat domains 1","NP_849143.1//dynein assembly factor with WDR repeat domains 1 isoform 1 [Homo sapiens]","1//3;2//1"]
[5971,2297,11.01,30.72,1.48036374715679,{"v":1.04943824554913E-60,"d":"1.05E-60"},"Up",{"v":1.136552E-62,"d":"1.14E-62"},"RELB","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005815//microtubule organizing center;GO:0043234//protein complex;GO:0005829//cytosol;GO:0033256//I-kappaB/NF-kappaB complex","GO:0003677//DNA binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0003714//transcription corepressor activity;GO:0042802//identical protein binding;GO:0019901//protein kinase binding;GO:0003682//chromatin binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0001047//core promoter binding","GO:0038061//NIK/NF-kappaB signaling;GO:0034097//response to cytokine;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0032922//circadian regulation of gene expression;GO:0045087//innate immune response;GO:0019882//antigen processing and presentation;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0006351//transcription, DNA-templated;GO:0006954//inflammatory response;GO:0045063//T-helper 1 cell differentiation;GO:0071470//cellular response to osmotic stress;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0032688//negative regulation of interferon-beta production;GO:0043011//myeloid dendritic cell differentiation","K09253//transcription factor RelB","NP_006500.2//transcription factor RelB [Homo sapiens]","3//A2MP1"]
[64135,3617,0.18,0.5,1.47393118833241,0.0185279031054227,"*",0.00688736,"IFIH1","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0004386//helicase activity;GO:0003725//double-stranded RNA binding;GO:0016787//hydrolase activity;GO:0008270//zinc ion binding;GO:0043021//ribonucleoprotein complex binding;GO:0003727//single-stranded RNA binding","GO:0016925//protein sumoylation;GO:0060760//positive regulation of response to cytokine stimulus;GO:0035549//positive regulation of interferon-beta secretion;GO:0016579//protein deubiquitination;GO:0045087//innate immune response;GO:0039530//MDA-5 signaling pathway;GO:2000778//positive regulation of interleukin-6 secretion;GO:0039528//cytoplasmic pattern recognition receptor signaling pathway in response to virus;GO:0032728//positive regulation of interferon-beta production;GO:0009597//detection of virus;GO:0071360//cellular response to exogenous dsRNA;GO:0051607//defense response to virus;GO:0032727//positive regulation of interferon-alpha production;GO:0016032//viral process;GO:0034344//regulation of type III interferon production;GO:1904469//positive regulation of tumor necrosis factor secretion;GO:1902741//positive regulation of interferon-alpha secretion;GO:0032480//negative regulation of type I interferon production;GO:0009615//response to virus","K12647//interferon-induced helicase C domain-containing protein 1 [EC:3.6.4.13]","NP_071451.2//interferon-induced helicase C domain-containing protein 1 [Homo sapiens]","3//A2MP1"]
[29950,1213,17.96,49.65,1.46700636767459,{"v":3.66637480174672e-50,"d":"3.67E-50"},"Up",{"v":5.25604e-52,"d":"5.26E-52"},"SERTAD1","GO:0005634//nucleus;GO:0005737//cytoplasm","NA","GO:0030308//negative regulation of cell growth;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0008284//positive regulation of cell proliferation","NA","NP_037508.2//SERTA domain-containing protein 1 [Homo sapiens]","3//A2MP1"]
[100131378,903,0.83,2.29,1.46416435675002,0.0161148471991772,"*",0.00588544,"C11orf91","GO:0043231//intracellular membrane-bounded organelle","NA","NA","K00894//ethanolamine kinase [EC:2.7.1.82];K10367//formin 1","NP_001160164.1//uncharacterized protein C11orf91 [Homo sapiens]","1//3"]
[340061,1960,0.49,1.35,1.46210575293562,0.00118791928779198,"*",0.000337472,"TMEM173","GO:0030667//secretory granule membrane;GO:0005654//nucleoplasm;GO:0005777//peroxisome;GO:0005741//mitochondrial outer membrane;GO:0048471//perinuclear region of cytoplasm;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0030659//cytoplasmic vesicle membrane","GO:0042802//identical protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0035438//cyclic-di-GMP binding;GO:0008134//transcription factor binding;GO:0042803//protein homodimerization activity;GO:0061507//cyclic-GMP-AMP binding;GO:0019901//protein kinase binding","GO:0032481//positive regulation of type I interferon production;GO:0032479//regulation of type I interferon production;GO:0002218//activation of innate immune response;GO:0032092//positive regulation of protein binding;GO:0035458//cellular response to interferon-beta;GO:0071407//cellular response to organic cyclic compound;GO:0043312//neutrophil degranulation;GO:0045087//innate immune response;GO:0033160//positive regulation of protein import into nucleus, translocation;GO:0071360//cellular response to exogenous dsRNA;GO:0051607//defense response to virus;GO:0016032//viral process;GO:0006915//apoptotic process;GO:0032608//interferon-beta production;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0002230//positive regulation of defense response to virus by host;GO:0042993//positive regulation of transcription factor import into nucleus","K12654//transmembrane protein 173","NP_001288667.1//stimulator of interferon genes protein isoform 2 [Homo sapiens];NP_938023.1//stimulator of interferon genes protein isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[54625,7713,3.94,10.85,1.46142750787547,{"v":1.27924158992806E-71,"d":"1.28E-71"},"Up",{"v":1.11315E-73,"d":"1.11E-73"},"PARP14","GO:0016020//membrane;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0070403//NAD+ binding;GO:0003950//NAD+ ADP-ribosyltransferase activity;GO:0019899//enzyme binding","GO:0006355//regulation of transcription, DNA-templated;GO:0060336//negative regulation of interferon-gamma-mediated signaling pathway;GO:0006351//transcription, DNA-templated;GO:0070212//protein poly-ADP-ribosylation;GO:0010629//negative regulation of gene expression;GO:0042532//negative regulation of tyrosine phosphorylation of STAT protein;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:1902216//positive regulation of interleukin-4-mediated signaling pathway;GO:0006471//protein ADP-ribosylation","K15261//poly [ADP-ribose] polymerase 10/14/15 [EC:2.4.2.30]","NP_060024.2//poly [ADP-ribose] polymerase 14 [Homo sapiens]","2//1"]
[129881,2187,0.04,0.11,1.4594316186373,0.531268036302162,"*",0.37379,"CCDC173","NA","NA","NA","K00476//aspartate beta-hydroxylase [EC:1.14.11.16]","NP_001078916.1//coiled-coil domain-containing protein 173 [Homo sapiens]","1//3"]
[8817,1999,0.16,0.44,1.4594316186373,0.150176893409035,"*",0.0761696,"FGF18","GO:0005730//nucleolus;GO:0005576//extracellular region","GO:0008083//growth factor activity;GO:0005111//type 2 fibroblast growth factor receptor binding;GO:0005105//type 1 fibroblast growth factor receptor binding","GO:0030324//lung development;GO:0001958//endochondral ossification;GO:0001525//angiogenesis;GO:0043406//positive regulation of MAP kinase activity;GO:0030949//positive regulation of vascular endothelial growth factor receptor signaling pathway;GO:0002063//chondrocyte development;GO:0001957//intramembranous ossification;GO:0032332//positive regulation of chondrocyte differentiation;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:2000546//positive regulation of endothelial cell chemotaxis to fibroblast growth factor;GO:0008284//positive regulation of cell proliferation","K04358//fibroblast growth factor","XP_014956713.1//PREDICTED: fibroblast growth factor 18 isoform X2 [Ovis aries]","2//1"]
[51296,2134,0.04,0.11,1.4594316186373,0.531031791177517,"*",0.37379,"SLC15A3","GO:0005765//lysosomal membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane","GO:0015333//peptide:proton symporter activity;GO:0005215//transporter activity","GO:0015031//protein transport;GO:0006811//ion transport","K14638//solute carrier family 15 (peptide/histidine transporter), member 3/4","NP_057666.1//solute carrier family 15 member 3 [Homo sapiens]","2//1"]
[633,2470,0.04,0.11,1.4594316186373,0.530183045640206,"*",0.37379,"BGN","GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0005737//cytoplasm;GO:0005578//proteinaceous extracellular matrix;GO:0005796//Golgi lumen;GO:0009986//cell surface;GO:0030133//transport vesicle;GO:0042383//sarcolemma;GO:0005576//extracellular region;GO:0043202//lysosomal lumen","GO:0005201//extracellular matrix structural constituent;GO:0004860//protein kinase inhibitor activity;GO:0005539//glycosaminoglycan binding;GO:0050840//extracellular matrix binding","GO:0019800//peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan;GO:0046426//negative regulation of JAK-STAT cascade;GO:0030208//dermatan sulfate biosynthetic process;GO:0030206//chondroitin sulfate biosynthetic process;GO:0001974//blood vessel remodeling;GO:0006469//negative regulation of protein kinase activity;GO:0030198//extracellular matrix organization;GO:0030207//chondroitin sulfate catabolic process;GO:0019221//cytokine-mediated signaling pathway;GO:0030203//glycosaminoglycan metabolic process","K08118//biglycan","XP_011857624.1//PREDICTED: biglycan isoform X1 [Mandrillus leucophaeus]",5]
[149297,2252,0.04,0.11,1.4594316186373,0.52952478361121,"*",0.37379,"FAM78B","NA","NA","NA","K17943//pumilio RNA-binding family","XP_008683918.1//PREDICTED: protein FAM78B [Ursus maritimus];XP_017454519.1//PREDICTED: LOW QUALITY PROTEIN: protein FAM78B isoform X1 [Rattus norvegicus]","4;1//3"]
[1613,2329,9.34,25.62,1.45577602063198,{"v":3.93973012695652e-50,"d":"3.94E-50"},"Up",{"v":5.67258e-52,"d":"5.67E-52"},"DAPK3","GO:0005884//actin filament;GO:0016605//PML body;GO:0005634//nucleus;GO:0045121//membrane raft;GO:0005737//cytoplasm","GO:0017048//Rho GTPase binding;GO:0008140//cAMP response element binding protein binding;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0008022//protein C-terminus binding;GO:0004674//protein serine/threonine kinase activity;GO:0043522//leucine zipper domain binding","GO:0007346//regulation of mitotic cell cycle;GO:0030335//positive regulation of cell migration;GO:0006355//regulation of transcription, DNA-templated;GO:0097190//apoptotic signaling pathway;GO:0035556//intracellular signal transduction;GO:0007088//regulation of mitotic nuclear division;GO:0071346//cellular response to interferon-gamma;GO:0051893//regulation of focal adhesion assembly;GO:0043065//positive regulation of apoptotic process;GO:0017148//negative regulation of translation;GO:0010506//regulation of autophagy;GO:0030182//neuron differentiation;GO:0006468//protein phosphorylation;GO:0006351//transcription, DNA-templated;GO:0008360//regulation of cell shape;GO:2000145//regulation of cell motility;GO:0006940//regulation of smooth muscle contraction;GO:0006915//apoptotic process;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0046777//protein autophosphorylation;GO:2000249//regulation of actin cytoskeleton reorganization;GO:0018107//peptidyl-threonine phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0016569//covalent chromatin modification;GO:2001241//positive regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0043519//regulation of myosin II filament organization;GO:0042981//regulation of apoptotic process","K08803//death-associated protein kinase [EC:2.7.11.1]","XP_012291390.1//death-associated protein kinase 3 isoform X1 [Aotus nancymaae]","2//1"]
[64170,2032,0.15,0.41,1.45066140900957,0.150084271666461,"*",0.0761696,"CARD9","GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0050700//CARD domain binding;GO:0042803//protein homodimerization activity","GO:0032494//response to peptidoglycan;GO:0046330//positive regulation of JNK cascade;GO:0032755//positive regulation of interleukin-6 production;GO:0009620//response to fungus;GO:0042534//regulation of tumor necrosis factor biosynthetic process;GO:0043330//response to exogenous dsRNA;GO:0032760//positive regulation of tumor necrosis factor production;GO:0050830//defense response to Gram-positive bacterium;GO:0045087//innate immune response;GO:0045408//regulation of interleukin-6 biosynthetic process;GO:0045076//regulation of interleukin-2 biosynthetic process;GO:0042493//response to drug;GO:0032495//response to muramyl dipeptide;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0051607//defense response to virus;GO:0032874//positive regulation of stress-activated MAPK cascade;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0042981//regulation of apoptotic process","K12794//caspase recruitment domain-containing protein 9","XP_011723066.1//PREDICTED: caspase recruitment domain-containing protein 9 isoform X1 [Macaca nemestrina]","4;3//A2MP1"]
[6758,1308,0.26,0.71,1.44930740136359,0.150195431477595,"*",0.0761696,"SSX5","GO:0005634//nucleus","GO:0003714//transcription corepressor activity;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:1903507//negative regulation of nucleic acid-templated transcription","K15625//protein SSX2;K15624//protein SSX1","XP_015299131.1//PREDICTED: protein SSX3 isoform X2 [Macaca fascicularis];AAC05821.1//SSX5 [Homo sapiens]","1//3;3//A2MP1"]
[3759,5397,0.35,0.95,1.44057259138598,{"v":4.78065153863767e-05,"d":"4.78E-05"},"Up",{"v":1.045674E-5,"d":"1.05E-05"},"KCNJ2","NA","NA","NA","K04996//potassium inwardly-rectifying channel subfamily J member 2","ELK12419.1//Inward rectifier potassium channel 2 [Pteropus alecto]","2//1"]
[100526737,923,7.6,20.62,1.43997300903716,{"v":6.81241949230769e-16,"d":"6.81E-16"},"Up",{"v":4.43528e-17,"d":"4.44E-17"},"RBM14-RBM4","NA","GO:0003723//RNA binding;GO:0008270//zinc ion binding","NA","K13187//RNA-binding protein 4;K13189//RNA-binding protein 14","NP_001185774.1//RBM14-RBM4 protein isoform 1 [Homo sapiens];NP_001185775.1//RBM14-RBM4 protein isoform 2 [Homo sapiens]","1//3"]
[30008,2096,0.34,0.92,1.43609911480667,0.0232612613883432,"*",8.89444E-3,"EFEMP2","NA","NA","NA","K19866//EGF-containing fibulin-like extracellular matrix protein 2","XP_011897030.1//PREDICTED: EGF-containing fibulin-like extracellular matrix protein 2 isoform X1 [Cercocebus atys]",4]
[25876,1597,0.3,0.81,1.43295940727611,0.0764171738875715,"*",0.0342954,"SPEF1","GO:0031514//motile cilium;GO:0005737//cytoplasm;GO:0005930//axoneme","GO:0008017//microtubule binding","GO:0016477//cell migration;GO:0007026//negative regulation of microtubule depolymerization","K19720//collagen, type III, alpha","NP_056232.2//sperm flagellar protein 1 [Homo sapiens]",4]
[27289,1665,7.56,20.4,1.43211101263779,{"v":7.53035928270042e-28,"d":"7.53E-28"},"Up",{"v":2.2345e-29,"d":"2.23E-29"},"RND1","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005622//intracellular;GO:0005737//cytoplasm;GO:0005912//adherens junction;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0005886//plasma membrane","GO:0005102//receptor binding;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0007015//actin filament organization;GO:0007264//small GTPase mediated signal transduction;GO:0007162//negative regulation of cell adhesion;GO:0016322//neuron remodeling","K07531//Rho family GTPase 1","NP_055285.1//rho-related GTP-binding protein Rho6 precursor [Homo sapiens]","3//A2MP1"]
[59335,2492,0.13,0.35,1.42884329880387,0.150213974123457,"*",0.0761696,"PRDM12","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_007453202.1//PREDICTED: PR domain zinc finger protein 12 [Lipotes vexillifer]","2//1"]
[92797,3621,0.35,0.94,1.42530583473267,1.33684724159021E-3,"*",3.83128E-4,"HELB","GO:0035861//site of double-strand break;GO:0005634//nucleus;GO:0005658//alpha DNA polymerase:primase complex;GO:0005662//DNA replication factor A complex;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0004004//ATP-dependent RNA helicase activity;GO:0005524//ATP binding;GO:0017116//single-stranded DNA-dependent ATP-dependent DNA helicase activity;GO:0043141//ATP-dependent 5'-3' DNA helicase activity","GO:0006396//RNA processing;GO:1903775//regulation of DNA double-strand break processing;GO:2000042//negative regulation of double-strand break repair via homologous recombination;GO:0006269//DNA replication, synthesis of RNA primer;GO:0006281//DNA repair;GO:0006260//DNA replication;GO:0006974//cellular response to DNA damage stimulus","K15254//DNA helicase B [EC:3.6.4.12]","NP_387467.2//DNA helicase B [Homo sapiens]",4]
[1490,2358,8.24,22.08,1.42202392959495,{"v":2.71483301438849E-42,"d":"2.71E-42"},"Up",{"v":4.7247e-44,"d":"4.72E-44"},"CTGF","GO:0043231//intracellular membrane-bounded organelle;GO:0005615//extracellular space;GO:0005938//cell cortex;GO:0005801//cis-Golgi network;GO:0005578//proteinaceous extracellular matrix;GO:0048471//perinuclear region of cytoplasm;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0005520//insulin-like growth factor binding;GO:0008083//growth factor activity;GO:0008022//protein C-terminus binding;GO:0005178//integrin binding;GO:0001968//fibronectin binding;GO:0008201//heparin binding","GO:0046330//positive regulation of JNK cascade;GO:0016477//cell migration;GO:0034059//response to anoxia;GO:0032967//positive regulation of collagen biosynthetic process;GO:0032355//response to estradiol;GO:0009749//response to glucose;GO:0019216//regulation of lipid metabolic process;GO:0001502//cartilage condensation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0045597//positive regulation of cell differentiation;GO:0009611//response to wounding;GO:0051385//response to mineralocorticoid;GO:0001558//regulation of cell growth;GO:0050867//positive regulation of cell activation;GO:0001525//angiogenesis;GO:0030154//cell differentiation;GO:0072593//reactive oxygen species metabolic process;GO:0010628//positive regulation of gene expression;GO:0007160//cell-matrix adhesion;GO:0007155//cell adhesion;GO:0008544//epidermis development;GO:0071897//DNA biosynthetic process;GO:0032330//regulation of chondrocyte differentiation;GO:0070542//response to fatty acid;GO:0060401//cytosolic calcium ion transport;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0030324//lung development;GO:0043200//response to amino acid;GO:0035556//intracellular signal transduction;GO:0010629//negative regulation of gene expression;GO:0001503//ossification;GO:0007229//integrin-mediated signaling pathway;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0070318//positive regulation of G0 to G1 transition;GO:0043434//response to peptide hormone;GO:0007267//cell-cell signaling;GO:0060452//positive regulation of cardiac muscle contraction;GO:0001894//tissue homeostasis;GO:0007568//aging;GO:0035988//chondrocyte proliferation;GO:0051496//positive regulation of stress fiber assembly;GO:0070278//extracellular matrix constituent secretion;GO:0060548//negative regulation of cell death;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0008284//positive regulation of cell proliferation","K06827//connective tissue growth factor","NP_001892.1//connective tissue growth factor precursor [Homo sapiens]","2//1"]
[3552,2947,0.03,0.08,1.41503749927884,0.531551808065521,"*",0.37379,"IL1A","GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005576//extracellular region","GO:0005125//cytokine activity;GO:0005507//copper ion binding;GO:0005149//interleukin-1 receptor binding","GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0032755//positive regulation of interleukin-6 production;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0010575//positive regulation of vascular endothelial growth factor production;GO:0051781//positive regulation of cell division;GO:0070498//interleukin-1-mediated signaling pathway;GO:0071639//positive regulation of monocyte chemotactic protein-1 production;GO:0008283//cell proliferation;GO:0035234//ectopic germ cell programmed cell death;GO:0045766//positive regulation of angiogenesis;GO:0045840//positive regulation of mitotic nuclear division;GO:0008285//negative regulation of cell proliferation;GO:0001660//fever generation;GO:0046688//response to copper ion;GO:0010628//positive regulation of gene expression;GO:0034605//cellular response to heat;GO:0006915//apoptotic process;GO:0006954//inflammatory response;GO:0050714//positive regulation of protein secretion;GO:2000391//positive regulation of neutrophil extravasation;GO:0045086//positive regulation of interleukin-2 biosynthetic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006955//immune response;GO:0019221//cytokine-mediated signaling pathway;GO:0050715//positive regulation of cytokine secretion;GO:0002248//connective tissue replacement involved in inflammatory response wound healing","K04383//interleukin 1 alpha","NP_000566.3//interleukin-1 alpha precursor [Homo sapiens]",4]
[27111,1484,0.06,0.16,1.41503749927884,0.53150449172156,"*",0.37379,"SDCBP2","GO:0070062//extracellular exosome;GO:0005730//nucleolus;GO:0016607//nuclear speck;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0008022//protein C-terminus binding;GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding","GO:0007399//nervous system development;GO:0046907//intracellular transport;GO:0008283//cell proliferation;GO:0035556//intracellular signal transduction","K17254//syntenin-1","NP_536737.3//syntenin-2 isoform a [Homo sapiens]","4;1//3;5"]
[2001,2039,0.06,0.16,1.41503749927884,0.531409884300463,"*",0.37379,"ELF5","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0030154//cell differentiation;GO:0060644//mammary gland epithelial cell differentiation;GO:0045596//negative regulation of cell differentiation;GO:0001712//ectodermal cell fate commitment;GO:0035019//somatic stem cell population maintenance;GO:0006366//transcription from RNA polymerase II promoter","K17101//E74-like factor 5","NP_001230010.1//ETS-related transcription factor Elf-5 isoform 4 [Homo sapiens];EPQ06656.1//ETS-related transcription factor Elf-5 [Myotis brandtii];NP_938195.1//ETS-related transcription factor Elf-5 isoform 1 [Homo sapiens];NP_001230009.1//ETS-related transcription factor Elf-5 isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[63950,3083,0.03,0.08,1.41503749927884,0.531126264009963,"*",0.37379,"DMRTA2","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0043565//sequence-specific DNA binding;GO:0046982//protein heterodimerization activity;GO:0003700//DNA binding transcription factor activity;GO:0042803//protein homodimerization activity","GO:0035914//skeletal muscle cell differentiation;GO:0021796//cerebral cortex regionalization;GO:0048665//neuron fate specification;GO:0071542//dopaminergic neuron differentiation;GO:0002052//positive regulation of neuroblast proliferation;GO:0007420//brain development","K19491//doublesex- and mab-3-related transcription factor 4/5","NP_115486.1//doublesex- and mab-3-related transcription factor A2 [Homo sapiens]","2//1"]
[9381,6345,0.03,0.08,1.41503749927884,0.43423267743459,"*",0.287794,"OTOF","GO:0016323//basolateral plasma membrane;GO:0030672//synaptic vesicle membrane;GO:0005829//cytosol;GO:0098793//presynapse;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0005789//endoplasmic reticulum membrane","GO:0005509//calcium ion binding","GO:0016079//synaptic vesicle exocytosis;GO:0061025//membrane fusion;GO:0007605//sensory perception of sound","K19949//otoferlin","NP_919303.1//otoferlin isoform c [Homo sapiens];NP_919224.1//otoferlin isoform a [Homo sapiens];XP_016860827.1//PREDICTED: otoferlin isoform X1 [Homo sapiens];NP_001274418.1//otoferlin isoform e [Homo sapiens];XP_016803687.1//PREDICTED: otoferlin isoform X4 [Pan troglodytes]","1//3;3//A2MP1;2//1"]
[6757,1456,0.21,0.56,1.41503749927884,0.175867577694989,"*",0.091611,"SSX2","GO:0005634//nucleus","GO:0003714//transcription corepressor activity;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:1903507//negative regulation of nucleic acid-templated transcription","K15625//protein SSX2;K15624//protein SSX1","XP_011925496.1//PREDICTED: protein SSX2 isoform X2 [Cercocebus atys];NP_003138.3//protein SSX2 isoform a [Homo sapiens];XP_009437384.2//PREDICTED: protein SSX2 isoform X2 [Pan troglodytes]","1//3;2//1;5"]
[6853,3172,0.03,0.08,1.41503749927884,0.530607079001155,"*",0.37379,"SYN1","GO:0030425//dendrite;GO:0048786//presynaptic active zone;GO:0008021//synaptic vesicle;GO:0043209//myelin sheath;GO:0030054//cell junction;GO:0043195//terminal bouton;GO:0014069//postsynaptic density;GO:0098993//anchored component of synaptic vesicle membrane;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0000795//synaptonemal complex","GO:0003779//actin binding;GO:0005524//ATP binding;GO:0003824//catalytic activity;GO:0048306//calcium-dependent protein binding;GO:0005215//transporter activity;GO:0019901//protein kinase binding","GO:2000300//regulation of synaptic vesicle exocytosis;GO:0007269//neurotransmitter secretion;GO:0007268//chemical synaptic transmission;GO:0097091//synaptic vesicle clustering;GO:0046928//regulation of neurotransmitter secretion","K19941//synapsin","NP_008881.2//synapsin-1 isoform Ia [Homo sapiens];NP_598006.1//synapsin-1 isoform Ib [Homo sapiens]","3//A2MP1;2//1"]
[221692,2462,0.06,0.16,1.41503749927884,0.434068676801057,"*",0.287794,"PHACTR1","GO:0005634//nucleus;GO:0005829//cytosol;GO:0030054//cell junction;GO:0045202//synapse","GO:0003779//actin binding;GO:0004864//protein phosphatase inhibitor activity;GO:0008157//protein phosphatase 1 binding","GO:0031032//actomyosin structure organization;GO:0031532//actin cytoskeleton reorganization;GO:0048870//cell motility;GO:0043149//stress fiber assembly","K17594//phosphatase and actin regulator 3","NP_001309243.1//phosphatase and actin regulator 1 isoform e [Homo sapiens];EAW55321.1//phosphatase and actin regulator 1, isoform CRA_b [Homo sapiens];XP_021792295.1//phosphatase and actin regulator 1 isoform X8 [Papio anubis];XP_021792287.1//phosphatase and actin regulator 1 isoform X2 [Papio anubis]","1//3;3//A2MP1;2//1"]
[6503,2872,0.03,0.08,1.41503749927884,0.53027721669627,"*",0.37379,"SLA","GO:0005768//endosome;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane","GO:0005070//SH3/SH2 adaptor activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005102//receptor binding","GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0016477//cell migration;GO:0038083//peptidyl-tyrosine autophosphorylation;GO:0030154//cell differentiation;GO:0042127//regulation of cell proliferation;GO:0045087//innate immune response","K08890//B lymphoid tyrosine kinase [EC:2.7.10.2];K08893//hemopoietic cell kinase [EC:2.7.10.2]","NP_001039022.2//src-like-adapter isoform b [Homo sapiens];XP_008953704.1//PREDICTED: src-like-adapter isoform X1 [Pan paniscus];NP_006739.2//src-like-adapter isoform c [Homo sapiens];NP_001269893.1//src-like-adapter isoform d [Homo sapiens]","1//3;3//A2MP1;2//1"]
[728464,2780,0.12,0.32,1.41503749927884,0.150065761026147,"*",0.0761696,"METTL24","GO:0005576//extracellular region","GO:0008168//methyltransferase activity","NA","K12816//pre-mRNA-processing factor 17","NP_001116836.1//methyltransferase-like protein 24 isoform 1 precursor [Homo sapiens]","1//3;2//1"]
[4121,5044,0.03,0.08,1.41503749927884,0.433945757598641,"*",0.287794,"MAN1A1","GO:0070062//extracellular exosome;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0000139//Golgi membrane","GO:0004571//mannosyl-oligosaccharide 1,2-alpha-mannosidase activity;GO:0005509//calcium ion binding","GO:0006491//N-glycan processing","K01230//mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]","XP_005267043.1//PREDICTED: mannosyl-oligosaccharide 1,2-alpha-mannosidase IA isoform X1 [Homo sapiens]","3//A2MP1"]
[136332,3147,0.03,0.08,1.41503749927884,0.52943087958858,"*",0.37379,"LRGUK","GO:0042995//cell projection;GO:0002177//manchette;GO:0001669//acrosomal vesicle","GO:0005524//ATP binding;GO:0016301//kinase activity","GO:0030154//cell differentiation;GO:0035082//axoneme assembly;GO:0007283//spermatogenesis","K17550//protein phosphatase 1 regulatory subunit 7","NP_653249.1//leucine-rich repeat and guanylate kinase domain-containing protein [Homo sapiens]","2//1"]
[10870,524,0.5,1.33,1.41142624572647,0.25531330793301,"*",0.1450622,"HCST","GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0043548//phosphatidylinositol 3-kinase binding;GO:0005102//receptor binding","GO:0006468//protein phosphorylation;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0050776//regulation of immune response","K07988//hematopoietic cell signal transducer","NP_055081.1//hematopoietic cell signal transducer isoform 1 precursor [Homo sapiens];NP_001007470.1//hematopoietic cell signal transducer isoform 2 precursor [Homo sapiens]","1//3;3//A2MP1"]
[9244,1824,0.4,1.06,1.40599235967584,0.0232650703389553,"*",8.89444E-3,"CRLF1","GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005576//extracellular region;GO:0097058//CRLF-CLCF1 complex","GO:0019955//cytokine binding;GO:0046982//protein heterodimerization activity","GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0043524//negative regulation of neuron apoptotic process;GO:0001657//ureteric bud development;GO:0010469//regulation of receptor activity;GO:2000672//negative regulation of motor neuron apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0035722//interleukin-12-mediated signaling pathway","K05060//interleukin 6 signal transducer;K05081//prolactin receptor","NP_004741.1//cytokine receptor-like factor 1 precursor [Homo sapiens]",4]
[119391,879,0.57,1.51,1.40551472516034,0.0211761817019868,"*",0.00800702,"GSTO2","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0004364//glutathione transferase activity;GO:0050610//methylarsonate reductase activity;GO:0042802//identical protein binding;GO:0045174//glutathione dehydrogenase (ascorbate) activity;GO:0016491//oxidoreductase activity","GO:0019852//L-ascorbic acid metabolic process;GO:0006749//glutathione metabolic process;GO:0009407//toxin catabolic process;GO:0006805//xenobiotic metabolic process;GO:0071243//cellular response to arsenic-containing substance;GO:0055114//oxidation-reduction process;GO:1901687//glutathione derivative biosynthetic process","K00799//glutathione S-transferase [EC:2.5.1.18]","NP_001177942.1//glutathione S-transferase omega-2 isoform 2 [Homo sapiens];AAO23573.1//glutathione transferase omega 2, partial [Homo sapiens];NP_899062.1//glutathione S-transferase omega-2 isoform 1 [Homo sapiens]","1//3"]
[9022,813,0.62,1.64,1.40335569423121,0.076427834765625,"*",0.0342954,"CLIC3","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0016604//nuclear body;GO:0034707//chloride channel complex;GO:0005737//cytoplasm","GO:0005244//voltage-gated ion channel activity;GO:0005254//chloride channel activity","GO:0007165//signal transduction;GO:0006821//chloride transport;GO:1902476//chloride transmembrane transport","K05023//chloride intracellular channel protein 3","NP_004660.2//chloride intracellular channel protein 3 [Homo sapiens]","2//1"]
[90634,1309,0.14,0.37,1.40209844357135,0.496207692782569,"*",0.342164,"N4BP2L1","NA","NA","NA","K15720//NEDD4-binding protein 2 [EC:3.-.-.-]","XP_016780635.1//PREDICTED: NEDD4-binding protein 2-like 1 isoform X5 [Pan troglodytes];XP_016780631.1//PREDICTED: NEDD4-binding protein 2-like 1 isoform X2 [Pan troglodytes];XP_016780634.1//PREDICTED: NEDD4-binding protein 2-like 1 isoform X4 [Pan troglodytes];XP_016780636.1//PREDICTED: NEDD4-binding protein 2-like 1 isoform X6 [Pan troglodytes];XP_001143836.3//PREDICTED: NEDD4-binding protein 2-like 1 isoform X1 [Pan troglodytes];XP_016780633.1//PREDICTED: NEDD4-binding protein 2-like 1 isoform X3 [Pan troglodytes];NP_001340557.1//NEDD4-binding protein 2-like 1 isoform 6 [Homo sapiens];XP_015294621.1//PREDICTED: NEDD4-binding protein 2-like 1 isoform X5 [Macaca fascicularis];XP_018895199.1//PREDICTED: NEDD4-binding protein 2-like 1 isoform X2 [Gorilla gorilla gorilla];NP_001340556.1//NEDD4-binding protein 2-like 1 isoform 5 [Homo sapiens];NP_001340560.1//NEDD4-binding protein 2-like 1 isoform 9 [Homo sapiens]","1//3;2//1"]
[27010,2462,0.14,0.37,1.40209844357135,0.150121306650216,"*",0.0761696,"TPK1","GO:0005829//cytosol","GO:0030975//thiamine binding;GO:0004788//thiamine diphosphokinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity","GO:0042723//thiamine-containing compound metabolic process;GO:0006772//thiamine metabolic process;GO:0009229//thiamine diphosphate biosynthetic process","K00949//thiamine pyrophosphokinase [EC:2.7.6.2]","XP_015426472.1//PREDICTED: thiamin pyrophosphokinase 1 isoform X3 [Myotis davidii];NP_001035947.1//thiamin pyrophosphokinase 1 isoform b [Homo sapiens];NP_001337812.1//thiamin pyrophosphokinase 1 isoform d [Homo sapiens];NP_001337810.1//thiamin pyrophosphokinase 1 isoform c [Homo sapiens];XP_012302990.1//thiamin pyrophosphokinase 1 isoform X1 [Aotus nancymaae];XP_021520956.1//thiamin pyrophosphokinase 1 isoform X2 [Aotus nancymaae];XP_011514333.1//PREDICTED: thiamin pyrophosphokinase 1 isoform X1 [Homo sapiens]","1//3;3//A2MP1"]
[79094,1487,7.83,20.6,1.39556012477954,{"v":2.69215692786325e-24,"d":"2.69E-24"},"Up",{"v":9.85922e-26,"d":"9.86E-26"},"CHAC1","GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005802//trans-Golgi network","GO:0003839//gamma-glutamylcyclotransferase activity;GO:0016829//lyase activity;GO:0005112//Notch binding","GO:0006986//response to unfolded protein;GO:0010955//negative regulation of protein processing;GO:0022008//neurogenesis;GO:0006751//glutathione catabolic process;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0045746//negative regulation of Notch signaling pathway;GO:0007219//Notch signaling pathway;GO:0006750//glutathione biosynthetic process","K07232//cation transport protein ChaC","NP_077016.2//glutathione-specific gamma-glutamylcyclotransferase 1 isoform a [Homo sapiens];NP_001136248.1//glutathione-specific gamma-glutamylcyclotransferase 1 isoform b [Homo sapiens]","3//A2MP1;5"]
[5699,1019,12.76,33.5,1.39253276646763,{"v":2.25388186821705E-26,"d":"2.25E-26"},"Up",{"v":7.2806e-28,"d":"7.28E-28"},"PSMB10","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000502//proteasome complex;GO:1990111//spermatoproteasome complex;GO:0005737//cytoplasm;GO:0005839//proteasome core complex;GO:0005829//cytosol;GO:0019774//proteasome core complex, beta-subunit complex","GO:0004298//threonine-type endopeptidase activity","GO:0043687//post-translational protein modification;GO:0038061//NIK/NF-kappaB signaling;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0006521//regulation of cellular amino acid metabolic process;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition;GO:0006959//humoral immune response;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0016579//protein deubiquitination;GO:0043488//regulation of mRNA stability;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0000209//protein polyubiquitination;GO:0000902//cell morphogenesis;GO:0055085//transmembrane transport;GO:0000165//MAPK cascade;GO:0050852//T cell receptor signaling pathway;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0016032//viral process;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0042098//T cell proliferation;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:1902036//regulation of hematopoietic stem cell differentiation","K02733//20S proteasome subunit beta 10 [EC:3.4.25.1]","NP_002792.1//proteasome subunit beta type-10 precursor [Homo sapiens]","3//A2MP1"]
[100271927,2794,0.52,1.36,1.38702312310925,0.000994973427230047,"Up",0.00027861,"RASA4B","GO:0005829//cytosol;GO:0005622//intracellular;GO:0031235//intrinsic component of the cytoplasmic side of the plasma membrane","GO:0046872//metal ion binding;GO:0005096//GTPase activator activity","GO:0046580//negative regulation of Ras protein signal transduction;GO:0000165//MAPK cascade;GO:0071277//cellular response to calcium ion;GO:0035556//intracellular signal transduction;GO:0034260//negative regulation of GTPase activity","K17630//Ras GTPase-activating protein 4","NP_001264264.1//ras GTPase-activating protein 4B [Homo sapiens]","1//3"]
[255488,5036,0.05,0.13,1.37851162325373,0.255341441630854,"*",0.1450622,"RNF144B","NA","NA","NA","K11975//E3 ubiquitin-protein ligase RNF144 [EC:2.3.2.27]","CAD38622.1//hypothetical protein, partial [Homo sapiens]","3//A2MP1"]
[148103,3115,0.1,0.26,1.37851162325373,0.216492992807746,"*",0.1175844,"ZNF599","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_003997989.1//PREDICTED: zinc finger protein 599 isoform X1 [Felis catus]","2//1"]
[286527,1809,0.82,2.13,1.37715761560775,0.226319080358969,"*",0.1247206,"TMSB15B","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein;K01368//cathepsin S [EC:3.4.22.27];K11252//histone H2B;K05764//thymosin, beta 4","XP_009235141.1//PREDICTED: thymosin beta-15A isoform X1 [Pongo abelii];XP_002930139.2//PREDICTED: thymosin beta-15A [Ailuropoda melanoleuca];XP_011890510.1//PREDICTED: ras-related protein Rab-9B isoform X1 [Cercocebus atys]","1//3;3//A2MP1"]
[388555,662,0.64,1.66,1.37503943134692,0.128463193614304,"*",0.062969,"IGFL3","GO:0005615//extracellular space","GO:0005102//receptor binding","NA","NA","NP_997276.1//insulin growth factor-like family member 3 precursor [Homo sapiens]","1//3"]
[127544,2692,9.76,25.26,1.37190158622467,{"v":5.6279984953271e-52,"d":"5.63E-52"},"Up",{"v":7.5397e-54,"d":"7.54E-54"},"RNF19B","GO:0000151//ubiquitin ligase complex;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0044194//cytolytic granule;GO:0005789//endoplasmic reticulum membrane","GO:0061630//ubiquitin protein ligase activity;GO:0046872//metal ion binding;GO:0004842//ubiquitin-protein transferase activity;GO:0031624//ubiquitin conjugating enzyme binding","GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0000209//protein polyubiquitination;GO:0002250//adaptive immune response","K11973//E3 ubiquitin-protein ligase RNF19B [EC:2.3.2.27]","NP_001287755.1//E3 ubiquitin-protein ligase RNF19B isoform c [Homo sapiens];NP_699172.2//E3 ubiquitin-protein ligase RNF19B isoform a [Homo sapiens];NP_001120833.1//E3 ubiquitin-protein ligase RNF19B isoform b [Homo sapiens]","1//3;3//A2MP1;2//1"]
[597,899,2.75,7.08,1.36431774167098,{"v":1.63876613898411e-05,"d":"1.64E-05"},"Up",{"v":3.2921e-06,"d":"3.29E-06"},"BCL2A1","GO:0005741//mitochondrial outer membrane","GO:0046982//protein heterodimerization activity;GO:0051400//BH domain binding;GO:0042803//protein homodimerization activity;GO:0015267//channel activity","GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0043066//negative regulation of apoptotic process;GO:0007568//aging;GO:0008053//mitochondrial fusion;GO:0043065//positive regulation of apoptotic process;GO:0021987//cerebral cortex development;GO:0001836//release of cytochrome c from mitochondria","K02162//hematopoietic Bcl-2-related protein A1","NP_001108207.1//bcl-2-related protein A1 isoform 2 [Homo sapiens];NP_004040.1//bcl-2-related protein A1 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[9148,4315,0.07,0.18,1.36257007938471,0.216542910491123,"*",0.1175844,"NEURL1","GO:0043197//dendritic spine;GO:0097440//apical dendrite;GO:0014069//postsynaptic density;GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0043204//perikaryon","GO:0061630//ubiquitin protein ligase activity;GO:0045183//translation factor activity, non-nucleic acid binding","GO:0007595//lactation;GO:0051491//positive regulation of filopodium assembly;GO:0006513//protein monoubiquitination;GO:0045741//positive regulation of epidermal growth factor-activated receptor activity;GO:0071230//cellular response to amino acid stimulus;GO:0048170//positive regulation of long-term neuronal synaptic plasticity;GO:0043065//positive regulation of apoptotic process;GO:0060999//positive regulation of dendritic spine development;GO:0007288//sperm axoneme assembly;GO:0045746//negative regulation of Notch signaling pathway;GO:0090129//positive regulation of synapse maturation;GO:0008285//negative regulation of cell proliferation","K01931//protein neuralized [EC:2.3.2.27]","XP_017707228.1//PREDICTED: E3 ubiquitin-protein ligase NEURL1 isoform X1 [Rhinopithecus bieti]",4]
[1815,1378,0.53,1.36,1.35954238668714,0.0332759199186992,"*",0.0133237,"DRD4","GO:0016020//membrane;GO:0098794//postsynapse;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane","GO:0004952//dopamine neurotransmitter receptor activity;GO:0015459//potassium channel regulator activity;GO:0042802//identical protein binding;GO:0008144//drug binding;GO:0035240//dopamine binding;GO:0017124//SH3 domain binding;GO:0001591//dopamine neurotransmitter receptor activity, coupled via Gi/Go","GO:0050709//negative regulation of protein secretion;GO:0008344//adult locomotory behavior;GO:0007195//adenylate cyclase-inhibiting dopamine receptor signaling pathway;GO:0042053//regulation of dopamine metabolic process;GO:0007212//dopamine receptor signaling pathway;GO:0050482//arachidonic acid secretion;GO:0007194//negative regulation of adenylate cyclase activity;GO:0042417//dopamine metabolic process;GO:0030818//negative regulation of cAMP biosynthetic process;GO:0006874//cellular calcium ion homeostasis;GO:0034776//response to histamine;GO:0048149//behavioral response to ethanol;GO:0035176//social behavior;GO:0000187//activation of MAPK activity;GO:0048148//behavioral response to cocaine;GO:0060080//inhibitory postsynaptic potential;GO:0048511//rhythmic process;GO:0001662//behavioral fear response;GO:0042752//regulation of circadian rhythm;GO:0001975//response to amphetamine;GO:1901386//negative regulation of voltage-gated calcium channel activity;GO:0032417//positive regulation of sodium:proton antiporter activity;GO:0033674//positive regulation of kinase activity;GO:0051586//positive regulation of dopamine uptake involved in synaptic transmission;GO:0042596//fear response","K04147//dopamine receptor D4","NP_000788.2//D(4) dopamine receptor [Homo sapiens]","3//A2MP1"]
[2894,5849,0.09,0.23,1.3536369546147,0.0924896761569689,"*",0.0427882,"GRID1","GO:0070062//extracellular exosome;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0045211//postsynaptic membrane","GO:0004970//ionotropic glutamate receptor activity;GO:0005234//extracellularly glutamate-gated ion channel activity","GO:0035176//social behavior","K05206//glutamate receptor delta-1 subunit","NP_060021.1//glutamate receptor ionotropic, delta-1 precursor [Homo sapiens]","2//1"]
[348645,1719,0.09,0.23,1.3536369546147,0.434314724232404,"*",0.287794,"C22orf34","NA","NA","NA","K19721//collagen, type V/XI/XXIV/XXVII, alpha","NP_001276851.1//uncharacterized protein C22orf34 [Homo sapiens]","2//1"]
[130,1400,0.09,0.23,1.3536369546147,0.255257059131967,"*",0.1450622,"ADH6","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0004022//alcohol dehydrogenase (NAD) activity;GO:0008270//zinc ion binding;GO:0004024//alcohol dehydrogenase activity, zinc-dependent;GO:0016491//oxidoreductase activity","GO:0006069//ethanol oxidation;GO:0045471//response to ethanol","K13952//alcohol dehydrogenase 6 [EC:1.1.1.1]","NP_001095940.1//alcohol dehydrogenase 6 isoform 1 [Homo sapiens];NP_000663.1//alcohol dehydrogenase 6 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[79934,2181,25.05,63.8,1.34874582056966,{"v":9.02207970222222e-103,"d":"9.02E-103"},"Up",{"v":5.08318E-105,"d":"5.08E-105"},"COQ8B","GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0031966//mitochondrial membrane;GO:0005886//plasma membrane","GO:0005524//ATP binding;GO:0016301//kinase activity","GO:0006744//ubiquinone biosynthetic process;GO:0021692//cerebellar Purkinje cell layer morphogenesis","K08869//aarF domain-containing kinase","NP_001136027.1//atypical kinase COQ8B, mitochondrial isoform b [Homo sapiens];NP_079152.3//atypical kinase COQ8B, mitochondrial isoform a [Homo sapiens]","3//A2MP1;2//1"]
[8510,1246,0.13,0.33,1.34395440121736,0.434437852579853,"*",0.287794,"MMP23B","GO:0031012//extracellular matrix;GO:0005622//intracellular;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005578//proteinaceous extracellular matrix","GO:0008237//metallopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding","GO:0000003//reproduction;GO:0006508//proteolysis","K08001//matrix metalloproteinase-23 (CA-MMP) [EC:3.4.24.-]","XP_011786394.1//PREDICTED: matrix metalloproteinase-23 [Colobus angolensis palliatus]","1//3"]
[55647,1543,0.79,1.99,1.33284387236655,0.0045633830743349,"*",1.460374E-3,"RAB20","GO:0045335//phagocytic vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0005794//Golgi apparatus;GO:0030670//phagocytic vesicle membrane;GO:0005886//plasma membrane;GO:0005769//early endosome","GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0090385//phagosome-lysosome fusion;GO:0030100//regulation of endocytosis;GO:0090383//phagosome acidification;GO:0015031//protein transport","K07911//Ras-related protein Rab-20","NP_060287.1//ras-related protein Rab-20 [Homo sapiens]","2//1"]
[2172,596,0.29,0.73,1.33184356375245,0.434191665659237,"*",0.287794,"FABP6","GO:0016020//membrane;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0008289//lipid binding;GO:0032052//bile acid binding;GO:0005215//transporter activity","GO:0019433//triglyceride catabolic process;GO:0015721//bile acid and bile salt transport;GO:0008285//negative regulation of cell proliferation;GO:0006629//lipid metabolic process","K08755//fatty acid-binding protein 6, ileal (gastrotropin)","XP_008970657.1//PREDICTED: gastrotropin isoform X2 [Pan paniscus];NP_001035532.1//gastrotropin isoform 1 [Homo sapiens]","1//3;2//1"]
[92162,880,0.31,0.78,1.33120590847537,0.203243206040033,"*",0.1086958,"TMEM88","GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0030165//PDZ domain binding","GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0072659//protein localization to plasma membrane;GO:0007275//multicellular organism development;GO:0016055//Wnt signaling pathway;GO:0050821//protein stabilization","K16628//collagen, type VII, alpha","NP_981956.1//transmembrane protein 88 isoform 1 [Homo sapiens];XP_018868687.1//PREDICTED: transmembrane protein 88 isoform X2 [Gorilla gorilla gorilla]","1//3"]
[5366,1954,5.59,14.06,1.33067640622935,{"v":1.92953550280374E-20,"d":"1.93E-20"},"Up",{"v":9.04734e-22,"d":"9.05E-22"},"PMAIP1","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005739//mitochondrion","NA","GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:0071456//cellular response to hypoxia;GO:0042149//cellular response to glucose starvation;GO:0043331//response to dsRNA;GO:0010498//proteasomal protein catabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0043517//positive regulation of DNA damage response, signal transduction by p53 class mediator;GO:0001836//release of cytochrome c from mitochondria;GO:0010907//positive regulation of glucose metabolic process;GO:0051607//defense response to virus;GO:0046902//regulation of mitochondrial membrane permeability;GO:0072593//reactive oxygen species metabolic process;GO:0032461//positive regulation of protein oligomerization;GO:1902043//positive regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process","K10131//phorbol-12-myristate-13-acetate-induced protein 1","XP_004059533.1//PREDICTED: phorbol-12-myristate-13-acetate-induced protein 1 isoform X1 [Gorilla gorilla gorilla]","2//1"]
[6345,4241,0.37,0.93,1.32970544547908,0.000858559013611615,"Up",2.36918E-4,"SRL","GO:0033018//sarcoplasmic reticulum lumen","GO:0005525//GTP binding","NA","K12483//EH domain-containing protein 1;K06236//collagen, type I, alpha","NP_001092284.1//sarcalumenin isoform 1 precursor [Homo sapiens];XP_011715915.1//PREDICTED: sarcalumenin isoform X2 [Macaca nemestrina];XP_017741887.1//PREDICTED: sarcalumenin isoform X1 [Rhinopithecus bieti]","1//3"]
[11074,2065,0.93,2.33,1.32502733354625,0.000283996920728361,"Up",{"v":7.12748e-05,"d":"7.13E-05"},"TRIM31","NA","NA","NA","K12011//tripartite motif-containing protein 31 [EC:2.3.2.27]","XP_009449161.2//PREDICTED: E3 ubiquitin-protein ligase TRIM31 isoform X1 [Pan troglodytes]",4]
[27128,3223,0.1,0.25,1.32192809488736,0.216567877966102,"*",0.1175844,"CYTH4","GO:0005886//plasma membrane","GO:0005086//ARF guanyl-nucleotide exchange factor activity","GO:0032012//regulation of ARF protein signal transduction","K18441//cytohesin","ELV11714.1//Cytohesin-4 [Tupaia chinensis];XP_004279495.1//PREDICTED: cytohesin-4 isoform X1 [Orcinus orca]","4;1//3"]
[273,3300,0.02,0.05,1.32192809488736,0.735911027114887,"*",0.623548,"AMPH","GO:0030672//synaptic vesicle membrane;GO:0008021//synaptic vesicle;GO:0031256//leading edge membrane;GO:0005829//cytosol;GO:0030054//cell junction;GO:0015629//actin cytoskeleton","GO:0005543//phospholipid binding","GO:0006897//endocytosis;GO:0007268//chemical synaptic transmission;GO:0061024//membrane organization","K12562//amphiphysin","NP_647477.1//amphiphysin isoform 2 [Homo sapiens];NP_001626.1//amphiphysin isoform 1 [Homo sapiens]","3//A2MP1;2//1"]
[6340,3516,0.02,0.05,1.32192809488736,0.735584945868104,"*",0.623548,"SCNN1G","GO:0070062//extracellular exosome;GO:0005654//nucleoplasm;GO:0034706//sodium channel complex;GO:0005730//nucleolus;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane","GO:0050699//WW domain binding;GO:0015280//ligand-gated sodium channel activity","GO:0050891//multicellular organismal water homeostasis;GO:0055078//sodium ion homeostasis","K04827//amiloride-sensitive sodium channel subunit gamma","XP_005591514.1//PREDICTED: amiloride-sensitive sodium channel subunit gamma [Macaca fascicularis]","3//A2MP1"]
[343505,1611,0.2,0.5,1.32192809488736,0.216517948772334,"*",0.1175844,"NBPF7","GO:0005737//cytoplasm","NA","NA","K22244//regenerating islet-derived protein 4;K16549//myomegalin","NP_001041445.1//putative neuroblastoma breakpoint family member 7 [Homo sapiens]","2//1"]
[338321,3484,0.02,0.05,1.32192809488736,0.734825212246404,"*",0.623548,"NLRP9","GO:0061702//inflammasome complex","GO:0005524//ATP binding","GO:0032741//positive regulation of interleukin-18 production;GO:0070269//pyroptosis;GO:0051607//defense response to virus;GO:0045087//innate immune response;GO:0006954//inflammatory response","K22265//NACHT, LRR and PYD domains-containing protein 4","NP_789790.2//NACHT, LRR and PYD domains-containing protein 9 [Homo sapiens]","3//A2MP1"]
[201799,3233,0.02,0.05,1.32192809488736,0.734771005606374,"*",0.623548,"TMEM154","GO:0016021//integral component of membrane","NA","NA","NA","NP_689893.1//transmembrane protein 154 precursor [Homo sapiens]","2//1"]
[1427,919,0.18,0.45,1.32192809488736,0.434109665344665,"*",0.287794,"CRYGS","NA","GO:0005212//structural constituent of eye lens","GO:0002009//morphogenesis of an epithelium;GO:0002088//lens development in camera-type eye","K13596//activin receptor type-2B [EC:2.7.11.30];K16810//TBCC domain-containing protein 1","XP_020029684.1//beta-crystallin S isoform X1 [Castor canadensis]","3//A2MP1"]
[51332,11748,0.02,0.05,1.32192809488736,0.255228944024672,"*",0.1450622,"SPTBN5","NA","NA","NA","K06115//spectrin beta","EAW92523.1//spectrin, beta, non-erythrocytic 5 [Homo sapiens]","3//A2MP1"]
[84281,3978,0.04,0.1,1.32192809488736,0.434027695996979,"*",0.287794,"C2orf88","GO:0005886//plasma membrane","GO:0034237//protein kinase A regulatory subunit binding","NA","K17580//cancer susceptibility candidate protein 1","NP_115697.2//small membrane A-kinase anchor protein [Homo sapiens]","1//3;2//1"]
[79949,3263,0.02,0.05,1.32192809488736,0.733526456440091,"*",0.623548,"PLEKHS1","NA","NA","NA","K10955//mucin-2;K04397//caspase 7 [EC:3.4.22.60]","XP_011538473.1//PREDICTED: pleckstrin homology domain-containing family S member 1 isoform X1 [Homo sapiens];NP_872407.1//pleckstrin homology domain-containing family S member 1 isoform 1 [Homo sapiens];XP_005270220.1//PREDICTED: pleckstrin homology domain-containing family S member 1 isoform X4 [Homo sapiens]","4;1//3"]
[644090,2211,0.08,0.2,1.32192809488736,0.4339048,"*",0.287794,"LOC644090","NA","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K02927//large subunit ribosomal protein L40e;K17985//activating molecule in BECN1-regulated autophagy protein 1;K01064//wingless-type MMTV integration site family, member 9","EAW53985.1//hCG2038711, partial [Homo sapiens]","1//3"]
[91608,3213,0.1,0.25,1.32192809488736,0.216468042595367,"*",0.1175844,"RASL10B","GO:0016020//membrane","GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0007165//signal transduction","K07851//Ras-like protein family member 10B","XP_009430660.1//PREDICTED: ras-like protein family member 10B isoform X1 [Pan troglodytes]","3//A2MP1"]
[10221,3190,14.62,36.44,1.31757964784961,{"v":1.67061025147059e-72,"d":"1.67E-72"},"Up",{"v":1.42233E-74,"d":"1.42E-74"},"TRIB1","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0031434//mitogen-activated protein kinase kinase binding;GO:0005524//ATP binding;GO:0004860//protein kinase inhibitor activity;GO:0004672//protein kinase activity;GO:0031625//ubiquitin protein ligase binding;GO:0055106//ubiquitin-protein transferase regulator activity;GO:0008134//transcription factor binding","GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0043433//negative regulation of DNA binding transcription factor activity;GO:0031665//negative regulation of lipopolysaccharide-mediated signaling pathway;GO:0032496//response to lipopolysaccharide;GO:0043405//regulation of MAP kinase activity;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0007254//JNK cascade;GO:0006469//negative regulation of protein kinase activity;GO:0014912//negative regulation of smooth muscle cell migration;GO:0045645//positive regulation of eosinophil differentiation;GO:0045651//positive regulation of macrophage differentiation;GO:0045659//negative regulation of neutrophil differentiation","K08814//tribbles homolog 1/2","NP_079471.1//tribbles homolog 1 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[60680,3754,0.21,0.52,1.30812229536233,0.110445014193548,"*",0.0525122,"CELF5","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0036002//pre-mRNA binding","GO:0006397//mRNA processing;GO:0000381//regulation of alternative mRNA splicing, via spliceosome","K13207//CUG-BP- and ETR3-like factor","NP_068757.2//CUGBP Elav-like family member 5 isoform 1 [Homo sapiens];BAD92304.1//bruno-like 5, RNA binding protein variant, partial [Homo sapiens]","1//3;3//A2MP1"]
[2266,1753,0.28,0.69,1.30116953472056,0.109350094911679,"*",0.05193,"FGG","GO:0070062//extracellular exosome;GO:0005788//endoplasmic reticulum lumen;GO:0005577//fibrinogen complex;GO:0005615//extracellular space;GO:0072562//blood microparticle;GO:0009897//external side of plasma membrane;GO:0031093//platelet alpha granule lumen;GO:0009986//cell surface;GO:0031091//platelet alpha granule;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0046872//metal ion binding;GO:0050839//cell adhesion molecule binding;GO:0030674//protein binding, bridging;GO:0005198//structural molecule activity;GO:0005102//receptor binding;GO:0042803//protein homodimerization activity","GO:0043687//post-translational protein modification;GO:0007596//blood coagulation;GO:0045921//positive regulation of exocytosis;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:0036345//platelet maturation;GO:0044267//cellular protein metabolic process;GO:0002576//platelet degranulation;GO:0045907//positive regulation of vasoconstriction;GO:0071347//cellular response to interleukin-1;GO:0071354//cellular response to interleukin-6;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0072378//blood coagulation, fibrin clot formation;GO:0090277//positive regulation of peptide hormone secretion;GO:0090331//negative regulation of platelet aggregation;GO:0034116//positive regulation of heterotypic cell-cell adhesion;GO:0042730//fibrinolysis;GO:0002224//toll-like receptor signaling pathway;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:0031639//plasminogen activation;GO:0051258//protein polymerization;GO:0050714//positive regulation of protein secretion;GO:0007160//cell-matrix adhesion;GO:0051592//response to calcium ion;GO:0009306//protein secretion;GO:0030198//extracellular matrix organization;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070527//platelet aggregation;GO:0043623//cellular protein complex assembly","K03905//fibrinogen gamma chain","AAB59531.1//fibrinogen gamma chain [Homo sapiens];NP_068656.2//fibrinogen gamma chain isoform gamma-B precursor [Homo sapiens]","2//1;5"]
[114571,2327,0.11,0.27,1.29545588352617,0.36458648541329,"*",0.225316,"SLC22A9","GO:0016323//basolateral plasma membrane;GO:0005887//integral component of plasma membrane","GO:0015143//urate transmembrane transporter activity;GO:0015301//anion:anion antiporter activity;GO:0005452//inorganic anion exchanger activity;GO:0015347//sodium-independent organic anion transmembrane transporter activity;GO:0015636//short-chain fatty acid transmembrane transporter activity","GO:0043252//sodium-independent organic anion transport;GO:0009914//hormone transport;GO:0015747//urate transport;GO:0015913//short-chain fatty acid import","K08206//MFS transporter, OCT family, solute carrier family 22 (organic anion/cation transporter), member 9/10/19/24/25","NP_543142.2//solute carrier family 22 member 9 [Homo sapiens]","2//1"]
[100130958,734,1.5,3.68,1.29474326556113,0.0125019345877378,"*",0.00444228,"SYCE1L","GO:0045111//intermediate filament cytoskeleton;GO:0000795//synaptonemal complex","NA","GO:0007130//synaptonemal complex assembly","K19534//synaptonemal complex central element protein 1","NP_001123451.1//synaptonemal complex central element protein 1-like isoform 1 [Homo sapiens];NP_001335853.1//synaptonemal complex central element protein 1-like isoform 2 [Homo sapiens]","1//3;2//1"]
[148932,2804,1.99,4.88,1.29411271701924,{"v":2.63525251073986e-10,"d":"2.64E-10"},"Up",{"v":2.76492E-11,"d":"2.76E-11"},"MOB3C","NA","NA","NA","K06685//MOB kinase activator 1","XP_016817891.1//PREDICTED: MOB kinase activator 3C isoform X1 [Pan troglodytes];NP_660322.2//MOB kinase activator 3C isoform 1 [Homo sapiens]","4;2//1"]
[149483,2240,0.29,0.71,1.29176612437711,0.0554111514285714,"*",0.0237962,"CCDC17","NA","NA","NA","K06236//collagen, type I, alpha","XP_001158794.3//PREDICTED: coiled-coil domain-containing protein 17 [Pan troglodytes]","1//3;2//1"]
[9214,2773,1.21,2.96,1.29059012835436,{"v":1.64387406432749E-6,"d":"1.64E-06"},"Up",{"v":2.8156e-07,"d":"2.82E-07"},"FCMR","GO:0016021//integral component of membrane;GO:0005576//extracellular region","NA","GO:0002376//immune system process;GO:0043066//negative regulation of apoptotic process;GO:0006968//cellular defense response","K13073//polymeric immunoglobulin receptor;K16851//high affinity immunoglobulin alpha and immunoglobulin mu Fc receptor","NP_001135945.1//fas apoptotic inhibitory molecule 3 isoform b [Homo sapiens];NP_001180267.1//fas apoptotic inhibitory molecule 3 isoform c precursor [Homo sapiens];NP_005440.1//fas apoptotic inhibitory molecule 3 isoform a precursor [Homo sapiens]","1//3;4"]
[90317,4386,0.07,0.17,1.28010791919274,0.303592796718517,"*",0.178385,"ZNF616","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","NP_848618.2//zinc finger protein 616 [Homo sapiens]",4]
[4016,2371,0.07,0.17,1.28010791919274,0.434396802041009,"*",0.287794,"LOXL1","GO:0031012//extracellular matrix;GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0001669//acrosomal vesicle;GO:0005604//basement membrane","GO:0016641//oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor;GO:0005507//copper ion binding","GO:0018277//protein deamination;GO:0030198//extracellular matrix organization;GO:0032496//response to lipopolysaccharide;GO:0055114//oxidation-reduction process;GO:0035904//aorta development","K14678//lysyl oxidase-like protein 1 [EC:1.4.3.-]","NP_005567.2//lysyl oxidase homolog 1 preproprotein [Homo sapiens]","3//A2MP1"]
[10235,2239,0.07,0.17,1.28010791919274,0.434355759259259,"*",0.287794,"RASGRP2","NA","NA","NA","K12361//RAS guanyl-releasing protein 2","XP_015289997.1//PREDICTED: RAS guanyl-releasing protein 2 isoform X1 [Macaca fascicularis];XP_005273764.3//PREDICTED: RAS guanyl-releasing protein 2 isoform X4 [Homo sapiens];AAF07219.1//guanine exchange factor MCG7 isoform 1 [Homo sapiens];AAI10307.1//RASGRP2 protein, partial [Homo sapiens]","1//3"]
[5837,3369,0.07,0.17,1.28010791919274,0.364549557783855,"*",0.225316,"PYGM","NA","GO:0102250//linear malto-oligosaccharide phosphorylase activity;GO:0030170//pyridoxal phosphate binding;GO:0008184//glycogen phosphorylase activity;GO:0102499//SHG alpha-glucan phosphorylase activity","GO:0005975//carbohydrate metabolic process","K00688//glycogen phosphorylase [EC:2.4.1.1]","XP_007070426.1//PREDICTED: glycogen phosphorylase, muscle form isoform X3 [Chelonia mydas];XP_019501148.1//PREDICTED: glycogen phosphorylase, muscle form [Hipposideros armiger]","1//3;3//A2MP1"]
[221472,3045,0.07,0.17,1.28010791919274,0.303769768996702,"*",0.1787362,"FGD2","GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0032587//ruffle membrane;GO:0030027//lamellipodium;GO:0005737//cytoplasm;GO:0001726//ruffle;GO:0031901//early endosome membrane;GO:0005829//cytosol;GO:0005794//Golgi apparatus","GO:0031267//small GTPase binding;GO:1901981//phosphatidylinositol phosphate binding;GO:0046872//metal ion binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005089//Rho guanyl-nucleotide exchange factor activity","GO:0046847//filopodium assembly;GO:0030036//actin cytoskeleton organization;GO:0008360//regulation of cell shape;GO:0043507//positive regulation of JUN kinase activity;GO:0043065//positive regulation of apoptotic process;GO:0043087//regulation of GTPase activity;GO:0007010//cytoskeleton organization;GO:0035023//regulation of Rho protein signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction","K05721//FYVE, RhoGEF and PH domain containing 2","NP_775829.2//FYVE, RhoGEF and PH domain-containing protein 2 [Homo sapiens]","3//A2MP1"]
[4791,3212,18.93,45.84,1.2759326330532,{"v":1.49139587041667E-99,"d":"1.49E-99"},"Up",{"v":8.96294e-102,"d":"8.96E-102"},"NFKB2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0033257//Bcl3/NF-kappaB2 complex;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003713//transcription coactivator activity;GO:0003682//chromatin binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0038061//NIK/NF-kappaB signaling;GO:0032481//positive regulation of type I interferon production;GO:0006355//regulation of transcription, DNA-templated;GO:0034097//response to cytokine;GO:0032496//response to lipopolysaccharide;GO:0002268//follicular dendritic cell differentiation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0048536//spleen development;GO:0045087//innate immune response;GO:0007165//signal transduction;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0048511//rhythmic process;GO:0007568//aging;GO:0006954//inflammatory response;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0002467//germinal center formation;GO:0030198//extracellular matrix organization;GO:0045944//positive regulation of transcription from RNA polymerase II promoter","K04469//nuclear factor of kappa light polypeptide gene enhancer in B-cells 2","NP_002493.3//nuclear factor NF-kappa-B p100 subunit isoform b [Homo sapiens];XP_016871767.1//PREDICTED: nuclear factor NF-kappa-B p100 subunit isoform X1 [Homo sapiens];NP_001309864.1//nuclear factor NF-kappa-B p100 subunit isoform c [Homo sapiens];XP_017799765.1//nuclear factor NF-kappa-B p100 subunit isoform X2 [Papio anubis];NP_001070962.1//nuclear factor NF-kappa-B p100 subunit isoform a [Homo sapiens]","1//3;3//A2MP1;2//1;5"]
[3428,2750,2.15,5.16,1.26303440583379,{"v":2.79222101070155e-10,"d":"2.79E-10"},"Up",{"v":2.9401e-11,"d":"2.94E-11"},"IFI16","GO:0016020//membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0016607//nuclear speck","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003723//RNA binding;GO:0042802//identical protein binding;GO:0008134//transcription factor binding;GO:0003690//double-stranded DNA binding;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0001047//core promoter binding","GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:0032481//positive regulation of type I interferon production;GO:0002218//activation of innate immune response;GO:0030099//myeloid cell differentiation;GO:0097202//activation of cysteine-type endopeptidase activity;GO:0001819//positive regulation of cytokine production;GO:0042149//cellular response to glucose starvation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0045071//negative regulation of viral genome replication;GO:0006914//autophagy;GO:0010506//regulation of autophagy;GO:0045087//innate immune response;GO:0030097//hemopoiesis;GO:0032731//positive regulation of interleukin-1 beta production;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045824//negative regulation of innate immune response;GO:0040029//regulation of gene expression, epigenetic;GO:0051607//defense response to virus;GO:0006351//transcription, DNA-templated;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0006954//inflammatory response;GO:2000117//negative regulation of cysteine-type endopeptidase activity;GO:0043392//negative regulation of DNA binding;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0071479//cellular response to ionizing radiation;GO:0030224//monocyte differentiation","K20914//gamma-interferon-inducible protein 16","BAD92226.1//Interferon, gamma-inducible protein 16 variant, partial [Homo sapiens];NP_001193496.1//gamma-interferon-inducible protein 16 isoform 1 [Homo sapiens]","1//3;2//1"]
[4320,2306,0.1,0.24,1.26303440583379,0.364660363120567,"*",0.225316,"MMP11","GO:0031012//extracellular matrix;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix;GO:0005796//Golgi lumen","GO:0004252//serine-type endopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding","GO:0022617//extracellular matrix disassembly;GO:0071711//basement membrane organization;GO:0006508//proteolysis;GO:0007275//multicellular organism development;GO:0030199//collagen fibril organization;GO:0045599//negative regulation of fat cell differentiation;GO:0030574//collagen catabolic process","K07993//matrix metalloproteinase-11 (stromelysin 3) [EC:3.4.24.-]","NP_005931.2//stromelysin-3 preproprotein [Homo sapiens]",4]
[6376,3341,0.05,0.12,1.26303440583379,0.434150661629993,"*",0.287794,"CX3CL1","GO:0005615//extracellular space;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0031737//CX3C chemokine receptor binding;GO:0005178//integrin binding;GO:0005102//receptor binding;GO:0008009//chemokine activity;GO:0048020//CCR chemokine receptor binding","GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0051041//positive regulation of calcium-independent cell-cell adhesion;GO:0050902//leukocyte adhesive activation;GO:0060055//angiogenesis involved in wound healing;GO:0050729//positive regulation of inflammatory response;GO:0043547//positive regulation of GTPase activity;GO:0071356//cellular response to tumor necrosis factor;GO:0033622//integrin activation;GO:0002523//leukocyte migration involved in inflammatory response;GO:0071346//cellular response to interferon-gamma;GO:0071347//cellular response to interleukin-1;GO:0048246//macrophage chemotaxis;GO:0045766//positive regulation of angiogenesis;GO:0002548//monocyte chemotaxis;GO:0006935//chemotaxis;GO:0032914//positive regulation of transforming growth factor beta1 production;GO:0007186//G-protein coupled receptor signaling pathway;GO:0048247//lymphocyte chemotaxis;GO:0030593//neutrophil chemotaxis;GO:0070098//chemokine-mediated signaling pathway;GO:0030595//leukocyte chemotaxis;GO:0030336//negative regulation of cell migration;GO:0006954//inflammatory response;GO:0007155//cell adhesion;GO:0006952//defense response;GO:0006955//immune response;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0019221//cytokine-mediated signaling pathway","K05508//C-X3-C motif chemokine 1","NP_002987.1//fractalkine isoform 1 precursor [Homo sapiens]","2//1;5"]
[64109,1503,0.2,0.48,1.26303440583379,0.303560454884415,"*",0.178385,"CRLF2","GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane","NA","NA","K05078//thymic stromal-derived lymphopoietin receptor","NP_071431.2//cytokine receptor-like factor 2 isoform 1 precursor [Homo sapiens]","3//A2MP1;2//1"]
[9605,2767,7.58,18.15,1.25969979471202,{"v":3.90153850899183e-34,"d":"3.90E-34"},"Up",{"v":8.96372e-36,"d":"8.96E-36"},"VPS9D1","NA","GO:0005215//transporter activity;GO:0005096//GTPase activator activity","GO:0015986//ATP synthesis coupled proton transport","K16628//collagen, type VII, alpha;K06236//collagen, type I, alpha;K21952//CASK-interacting protein","NP_004904.2//VPS9 domain-containing protein 1 [Homo sapiens]","2//1"]
[7454,1844,0.13,0.31,1.25375659224578,0.364438819765087,"*",0.225316,"WAS","GO:0012506//vesicle membrane;GO:0070062//extracellular exosome;GO:0005884//actin filament;GO:0005829//cytosol;GO:0005911//cell-cell junction;GO:0005622//intracellular;GO:0015629//actin cytoskeleton","GO:0031267//small GTPase binding;GO:0048365//Rac GTPase binding;GO:0042802//identical protein binding;GO:0043274//phospholipase binding;GO:0019901//protein kinase binding;GO:0030695//GTPase regulator activity;GO:0003779//actin binding;GO:0017124//SH3 domain binding","GO:0030048//actin filament-based movement;GO:0007596//blood coagulation;GO:0010591//regulation of lamellipodium assembly;GO:0007015//actin filament organization;GO:0051497//negative regulation of stress fiber assembly;GO:0008154//actin polymerization or depolymerization;GO:2000601//positive regulation of Arp2/3 complex-mediated actin nucleation;GO:2000146//negative regulation of cell motility;GO:0030041//actin filament polymerization;GO:0051492//regulation of stress fiber assembly;GO:0032488//Cdc42 protein signal transduction;GO:0016197//endosomal transport;GO:0042110//T cell activation;GO:0008064//regulation of actin polymerization or depolymerization;GO:0050852//T cell receptor signaling pathway;GO:0002625//regulation of T cell antigen processing and presentation;GO:0008544//epidermis development;GO:0006952//defense response;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0006955//immune response;GO:0006461//protein complex assembly","K05747//Wiskott-Aldrich syndrome protein","AAH02961.1//WAS protein, partial [Homo sapiens]","2//1"]
[55061,2672,0.13,0.31,1.25375659224578,0.628460563962983,"*",0.505908,"SUSD4","GO:0016021//integral component of membrane;GO:0005576//extracellular region","NA","GO:0006958//complement activation, classical pathway;GO:0030449//regulation of complement activation;GO:0045959//negative regulation of complement activation, classical pathway;GO:0045957//negative regulation of complement activation, alternative pathway;GO:0045087//innate immune response","K17495//CUB and sushi domain-containing protein","NP_060452.3//sushi domain-containing protein 4 isoform a precursor [Homo sapiens];NP_001032252.1//sushi domain-containing protein 4 isoform b precursor [Homo sapiens]","3//A2MP1;2//1"]
[59344,3251,0.67,1.59,1.24679376482658,0.000665475876594758,"Up",0.000179596,"ALOXE3","NA","NA","NA","K18684//hydroperoxy icosatetraenoate dehydratase/isomerase [EC:4.2.1.152 5.4.4.7]","XP_016787958.1//PREDICTED: hydroperoxide isomerase ALOXE3 [Pan troglodytes]","1//3;2//1"]
[2635,3086,0.68,1.61,1.24345403686428,0.000244132057417722,"Up",{"v":6.03682e-05,"d":"6.04E-05"},"GBP3","GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm;GO:0000139//Golgi membrane","GO:0019955//cytokine binding;GO:0019003//GDP binding;GO:0042803//protein homodimerization activity;GO:0003924//GTPase activity;GO:0003779//actin binding;GO:0051879//Hsp90 protein binding;GO:0005525//GTP binding;GO:0019899//enzyme binding;GO:0030507//spectrin binding","GO:0050860//negative regulation of T cell receptor signaling pathway;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:1903077//negative regulation of protein localization to plasma membrane;GO:1900025//negative regulation of substrate adhesion-dependent cell spreading;GO:0050848//regulation of calcium-mediated signaling;GO:0051607//defense response to virus;GO:0051260//protein homooligomerization;GO:1900041//negative regulation of interleukin-2 secretion","K20899//guanylate-binding protein 1/3/4/7","XP_021522106.1//guanylate-binding protein 3 isoform X2 [Aotus nancymaae];NP_001306110.1//guanylate-binding protein 3 isoform 4 [Homo sapiens];XP_011811446.1//PREDICTED: guanylate-binding protein 3 isoform X1 [Colobus angolensis palliatus]","1//3;2//1"]
[375704,1093,1.65,3.9,1.2410080995038,0.0015049331232166,"*",0.000435822,"ENHO","NA","NA","NA","NA","XP_016816258.1//PREDICTED: adropin isoform X1 [Pan troglodytes]","2//1"]
[84866,1546,0.14,0.33,1.23703919730085,0.495892554527309,"*",0.342164,"TMEM25","GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K11447//histone demethylase [EC:1.14.11.-];K01064//wingless-type MMTV integration site family, member 9","XP_016775328.1//PREDICTED: transmembrane protein 25 isoform X7 [Pan troglodytes];XP_012351331.1//PREDICTED: transmembrane protein 25 isoform X5 [Nomascus leucogenys];XP_016775329.1//PREDICTED: transmembrane protein 25 isoform X10 [Pan troglodytes];XP_014640594.1//PREDICTED: transmembrane protein 25 isoform X8 [Ceratotherium simum simum];XP_008971702.1//PREDICTED: transmembrane protein 25 isoform X5 [Pan paniscus];XP_009422324.1//PREDICTED: transmembrane protein 25 isoform X5 [Pan troglodytes];NP_001305686.1//transmembrane protein 25 isoform 7 precursor [Homo sapiens]","1//3;3//A2MP1"]
[124402,1428,67.8,159.54,1.23456100455512,{"v":2.08771516135593e-146,"d":"2.09E-146"},"Up",{"v":7.71098e-149,"d":"7.71E-149"},"UBALD1","NA","NA","NA","K16628//collagen, type VII, alpha;K03129//transcription initiation factor TFIID subunit 4;K20630//chimaerin;K15297//regulating synaptic membrane exocytosis protein 2","NP_660296.1//UBA-like domain-containing protein 1 isoform 1 [Homo sapiens];NP_001317396.1//UBA-like domain-containing protein 1 isoform 2 [Homo sapiens]","1//3;2//1"]
[100529261,2894,4.12,9.65,1.22788460497222,{"v":1.2025166991755E-18,"d":"1.20E-18"},"Up",{"v":6.39124e-20,"d":"6.39E-20"},"CHURC1-FNTB","GO:0005875//microtubule associated complex;GO:0005965//protein farnesyltransferase complex;GO:0005829//cytosol","GO:0019840//isoprenoid binding;GO:0004311//farnesyltranstransferase activity;GO:0008144//drug binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0004660//protein farnesyltransferase activity;GO:0042277//peptide binding","GO:0014070//response to organic cyclic compound;GO:0042127//regulation of cell proliferation;GO:0042060//wound healing;GO:0034097//response to cytokine;GO:0048146//positive regulation of fibroblast proliferation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0018343//protein farnesylation;GO:0051770//positive regulation of nitric-oxide synthase biosynthetic process;GO:0007275//multicellular organism development;GO:0010035//response to inorganic substance;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0008285//negative regulation of cell proliferation;GO:0045787//positive regulation of cell cycle","K05954//protein farnesyltransferase subunit beta [EC:2.5.1.58]","NP_001189487.1//CHURC1-FNTB protein isoform 2 [Homo sapiens];NP_001189488.1//CHURC1-FNTB protein isoform 1 [Homo sapiens]","1//3"]
[2212,2426,0.03,0.07,1.22239242133645,0.73601978511786,"*",0.623548,"FCGR2A","GO:0070062//extracellular exosome;GO:0030667//secretory granule membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0019864//IgG binding","GO:0043312//neutrophil degranulation;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis","K06472//low affinity immunoglobulin gamma Fc receptor II-a","NP_067674.2//low affinity immunoglobulin gamma Fc region receptor II-a isoform 2 precursor [Homo sapiens];NP_001129691.1//low affinity immunoglobulin gamma Fc region receptor II-a isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[7122,2332,0.09,0.21,1.22239242133645,0.303996173211244,"*",0.1787362,"CLDN5","GO:0070062//extracellular exosome;GO:0016327//apicolateral plasma membrane;GO:0030054//cell junction;GO:0043220//Schmidt-Lanterman incisure;GO:0033270//paranode region of axon;GO:0005911//cell-cell junction;GO:0005923//bicellular tight junction;GO:0016021//integral component of membrane;GO:0016328//lateral plasma membrane;GO:0005886//plasma membrane","GO:0042802//identical protein binding;GO:0005198//structural molecule activity","GO:0042552//myelination;GO:0007043//cell-cell junction assembly;GO:2000810//regulation of bicellular tight junction assembly;GO:0007612//learning;GO:0003151//outflow tract morphogenesis;GO:0045471//response to ethanol;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;GO:0060325//face morphogenesis;GO:0060021//palate development;GO:1903142//positive regulation of establishment of endothelial barrier","K06087//claudin","NP_003268.2//claudin-5 [Homo sapiens]","1//3;3//A2MP1"]
[3239,2341,0.03,0.07,1.22239242133645,0.734391782938878,"*",0.623548,"HOXD13","GO:0005634//nucleus","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0001158//enhancer sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0060602//branch elongation of an epithelium;GO:0009952//anterior/posterior pattern specification;GO:0006355//regulation of transcription, DNA-templated;GO:0042127//regulation of cell proliferation;GO:0060527//prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0060687//regulation of branching involved in prostate gland morphogenesis;GO:0042733//embryonic digit morphogenesis;GO:0048619//embryonic hindgut morphogenesis;GO:0030539//male genitalia development;GO:0033574//response to testosterone;GO:0060571//morphogenesis of an epithelial fold;GO:0007275//multicellular organism development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0001501//skeletal system development","K09298//homeobox protein HoxA/C/D13","NP_000514.2//homeobox protein Hox-D13 [Homo sapiens]","3//A2MP1"]
[101060200,2303,0.21,0.49,1.22239242133645,0.152442875651746,"*",0.0776052,"ZNF891","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_005339407.2//uncharacterized protein LOC101958065 [Ictidomys tridecemlineatus]","1//3"]
[83875,2795,0.09,0.21,1.22239242133645,0.364328149002936,"*",0.225316,"BCO2","GO:0005759//mitochondrial matrix;GO:0005622//intracellular;GO:0005739//mitochondrion","GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0046872//metal ion binding;GO:0102076//beta,beta-carotene-9',10'-cleaving oxygenase activity","GO:0016116//carotenoid metabolic process;GO:0016122//xanthophyll metabolic process;GO:0042574//retinal metabolic process;GO:0016119//carotene metabolic process;GO:0055114//oxidation-reduction process;GO:0016121//carotene catabolic process;GO:0042573//retinoic acid metabolic process;GO:0001523//retinoid metabolic process;GO:2000377//regulation of reactive oxygen species metabolic process;GO:0051881//regulation of mitochondrial membrane potential","K10252//beta,beta-carotene 9',10'-dioxygenase [EC:1.13.11.71]","NP_001243327.1//beta,beta-carotene 9',10'-oxygenase isoform d [Homo sapiens];XP_014971178.1//PREDICTED: beta,beta-carotene 9',10'-oxygenase isoform X1 [Macaca mulatta];NP_001032367.2//beta,beta-carotene 9',10'-oxygenase isoform b [Homo sapiens];NP_114144.4//beta,beta-carotene 9',10'-oxygenase isoform a [Homo sapiens]","1//3;2//1;5"]
[55584,2292,0.03,0.07,1.22239242133645,0.733418433988661,"*",0.623548,"CHRNA9","GO:0005887//integral component of plasma membrane;GO:0005892//acetylcholine-gated channel complex;GO:0030054//cell junction;GO:0005886//plasma membrane;GO:0045211//postsynaptic membrane","GO:0015276//ligand-gated ion channel activity;GO:0005262//calcium channel activity;GO:0022848//acetylcholine-gated cation-selective channel activity","GO:0042472//inner ear morphogenesis;GO:0050910//detection of mechanical stimulus involved in sensory perception of sound;GO:0007204//positive regulation of cytosolic calcium ion concentration","K04810//nicotinic acetylcholine receptor alpha-9","NP_060051.2//neuronal acetylcholine receptor subunit alpha-9 precursor [Homo sapiens]","3//A2MP1"]
[7092,7284,0.03,0.07,1.22239242133645,1.01432816213808,"*",0.997882,"TLL1","NA","GO:0004222//metalloendopeptidase activity;GO:0005509//calcium ion binding;GO:0008270//zinc ion binding","NA","K09608//tolloid-like protein 1 [EC:3.4.24.-]","XP_004392728.1//PREDICTED: tolloid-like protein 1 [Odobenus rosmarus divergens];XP_011714130.1//PREDICTED: tolloid-like protein 1 isoform X1 [Macaca nemestrina]","1//3;4"]
[440738,1192,3.98,9.28,1.22135637458392,{"v":1.33637909100257E-7,"d":"1.34E-07"},"Up",{"v":1.952616E-8,"d":"1.95E-08"},"MAP1LC3C","GO:0005829//cytosol;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0005776//autophagosome;GO:0000421//autophagosome membrane","GO:0031625//ubiquitin protein ligase binding","GO:0097352//autophagosome maturation;GO:0006995//cellular response to nitrogen starvation;GO:0009267//cellular response to starvation;GO:0000045//autophagosome assembly;GO:0035973//aggrephagy;GO:0000422//autophagy of mitochondrion","K10435//microtubule-associated protein 1 light chain","XP_011811086.1//PREDICTED: microtubule-associated proteins 1A/1B light chain 3C [Colobus angolensis palliatus]","2//1"]
[5371,3348,7.36,17.16,1.22127188144253,{"v":2.48497512307692E-34,"d":"2.48E-34"},"Up",{"v":5.66252E-36,"d":"5.66E-36"},"PML","GO:0016605//PML body;GO:0005654//nucleoplasm;GO:0000784//nuclear chromosome, telomeric region;GO:0016363//nuclear matrix;GO:0005737//cytoplasm;GO:0031901//early endosome membrane;GO:0042406//extrinsic component of endoplasmic reticulum membrane;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0000792//heterochromatin","GO:0003677//DNA binding;GO:0031625//ubiquitin protein ligase binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0050897//cobalt ion binding;GO:0008270//zinc ion binding;GO:0046332//SMAD binding;GO:0032183//SUMO binding","GO:0097191//extrinsic apoptotic signaling pathway;GO:0050713//negative regulation of interleukin-1 beta secretion;GO:0060444//branching involved in mammary gland duct morphogenesis;GO:0010332//response to gamma radiation;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:0045087//innate immune response;GO:0008285//negative regulation of cell proliferation;GO:0051457//maintenance of protein location in nucleus;GO:0045892//negative regulation of transcription, DNA-templated;GO:0043153//entrainment of circadian clock by photoperiod;GO:0007182//common-partner SMAD protein phosphorylation;GO:0048146//positive regulation of fibroblast proliferation;GO:0045345//positive regulation of MHC class I biosynthetic process;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0001666//response to hypoxia;GO:0006915//apoptotic process;GO:0010761//fibroblast migration;GO:1990830//cellular response to leukemia inhibitory factor;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:2000059//negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006461//protein complex assembly;GO:0030099//myeloid cell differentiation;GO:0007184//SMAD protein import into nucleus;GO:0007050//cell cycle arrest;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0001932//regulation of protein phosphorylation;GO:0090398//cellular senescence;GO:2000779//regulation of double-strand break repair;GO:0032922//circadian regulation of gene expression;GO:0071353//cellular response to interleukin-4;GO:0030155//regulation of cell adhesion;GO:0045165//cell fate commitment;GO:0030308//negative regulation of cell growth;GO:0030578//PML body organization;GO:0009411//response to UV;GO:0008631//intrinsic apoptotic signaling pathway in response to oxidative stress;GO:0016525//negative regulation of angiogenesis;GO:0048384//retinoic acid receptor signaling pathway;GO:1902187//negative regulation of viral release from host cell;GO:0032206//positive regulation of telomere maintenance;GO:0010522//regulation of calcium ion transport into cytosol;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0032469//endoplasmic reticulum calcium ion homeostasis;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest","K10054//probable transcription factor PML","NP_150253.2//protein PML isoform 11 [Homo sapiens];AAG50184.1//tripartite motif protein TRIM19 epsilon [Homo sapiens];NP_150243.2//protein PML isoform 2 [Homo sapiens];NP_002666.1//protein PML isoform 6 [Homo sapiens];NP_150242.1//protein PML isoform 9 [Homo sapiens];BAD92648.1//promyelocytic leukemia protein isoform 1 variant, partial [Homo sapiens];NP_150241.2//protein PML isoform 1 [Homo sapiens]","3//A2MP1;2//1"]
[377677,3855,0.71,1.65,1.21657509474113,{"v":5.92738472583826E-5,"d":"5.93E-05"},"Up",{"v":1.316908e-05,"d":"1.32E-05"},"CA13","GO:0043231//intracellular membrane-bounded organelle;GO:0005829//cytosol;GO:0043209//myelin sheath","GO:0008270//zinc ion binding;GO:0004089//carbonate dehydratase activity","GO:0006730//one-carbon metabolic process","K01672//carbonic anhydrase [EC:4.2.1.1]","XP_017705363.1//PREDICTED: carbonic anhydrase 13 [Rhinopithecus bieti]","2//1"]
[9048,1951,0.25,0.58,1.21412480535285,0.21140751280389,"*",0.1143194,"ARTN","GO:0005615//extracellular space;GO:0005622//intracellular;GO:0005576//extracellular region","GO:0008083//growth factor activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005102//receptor binding","GO:0000165//MAPK cascade;GO:0007165//signal transduction;GO:0050930//induction of positive chemotaxis;GO:0007405//neuroblast proliferation;GO:0061146//Peyer's patch morphogenesis;GO:0007422//peripheral nervous system development;GO:0007411//axon guidance;GO:0097021//lymphocyte migration into lymphoid organs","K16628//collagen, type VII, alpha;K05452//glial cell derived neurotrophic factor","NP_476431.2//artemin isoform 3 [Homo sapiens];NP_476432.2//artemin isoform 1 preproprotein [Homo sapiens]","1//3;2//1"]
[146378,815,0.16,0.37,1.20945336562895,0.530371421211583,"*",0.37379,"C16orf92","GO:0016021//integral component of membrane","NA","NA","NA","XP_001147584.2//PREDICTED: uncharacterized protein C16orf92 homolog [Pan troglodytes];NP_001103130.1//uncharacterized protein C16orf92 isoform 2 [Homo sapiens];NP_001340308.1//uncharacterized protein C16orf92 isoform 3 precursor [Homo sapiens]","1//3"]
[4616,1393,19.87,45.91,1.2082165594627,{"v":6.88591113594771e-40,"d":"6.89E-40"},"Up",{"v":1.319074e-41,"d":"1.32E-41"},"GADD45B","GO:0005634//nucleus;GO:0005737//cytoplasm","NA","GO:0046330//positive regulation of JNK cascade;GO:1900745//positive regulation of p38MAPK cascade;GO:0043065//positive regulation of apoptotic process;GO:0006469//negative regulation of protein kinase activity;GO:0000185//activation of MAPKKK activity;GO:0006950//response to stress;GO:0051726//regulation of cell cycle;GO:0000186//activation of MAPKK activity","K04402//growth arrest and DNA-damage-inducible protein","EAW69377.1//growth arrest and DNA-damage-inducible, beta, isoform CRA_b, partial [Homo sapiens]","3//A2MP1"]
[135152,1925,0.29,0.67,1.2081081953302,0.128881117836183,"*",0.0632384,"B3GAT2","NA","NA","NA","K10157//galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2 [EC:2.4.1.135]","XP_009240275.1//PREDICTED: LOW QUALITY PROTEIN: galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2 [Pongo abelii]","2//1"]
[4170,3939,39.91,92.2,1.20801647180543,{"v":6.863005464e-213,"d":"6.86E-213"},"Up",{"v":1.288908e-215,"d":"1.29E-215"},"MCL1","GO:0005759//mitochondrial matrix;GO:0016020//membrane;GO:0097136//Bcl-2 family protein complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005741//mitochondrial outer membrane;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005739//mitochondrion","GO:0015266//protein channel activity;GO:0051434//BH3 domain binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity","GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0001709//cell fate determination;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:1903378//positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway;GO:0034097//response to cytokine;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway;GO:0008637//apoptotic mitochondrial changes;GO:2001020//regulation of response to DNA damage stimulus;GO:0043066//negative regulation of apoptotic process;GO:2000811//negative regulation of anoikis;GO:0019725//cellular homeostasis;GO:0007275//multicellular organism development;GO:0010507//negative regulation of autophagy;GO:0042981//regulation of apoptotic process","K02539//myeloid leukemia cell differntiation protein MCL-1","NP_068779.1//induced myeloid leukemia cell differentiation protein Mcl-1 isoform 1 [Homo sapiens];NP_001184249.1//induced myeloid leukemia cell differentiation protein Mcl-1 isoform 3 [Homo sapiens];NP_877495.1//induced myeloid leukemia cell differentiation protein Mcl-1 isoform 2 [Homo sapiens]","4;1//3;2//1"]
[2785,962,0.26,0.6,1.20645087746743,0.364254405829369,"*",0.225316,"GNG3","NA","NA","NA","K04540//guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3","XP_011798065.1//PREDICTED: guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 [Colobus angolensis palliatus]",4]
[51734,1414,28.46,65.63,1.20541977123669,{"v":1.75764980851064E-57,"d":"1.76E-57"},"Up",{"v":2.0686e-59,"d":"2.07E-59"},"MSRB1","GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0005737//cytoplasm","GO:0003779//actin binding;GO:0046872//metal ion binding;GO:0033743//peptide-methionine (R)-S-oxide reductase activity;GO:0033745//L-methionine-(R)-S-oxide reductase activity;GO:0008270//zinc ion binding;GO:0070191//methionine-R-sulfoxide reductase activity","GO:0006979//response to oxidative stress;GO:0030091//protein repair;GO:0045087//innate immune response;GO:0030041//actin filament polymerization","K07305//peptide-methionine (R)-S-oxide reductase [EC:1.8.4.12]","NP_057416.1//methionine-R-sulfoxide reductase B1 [Homo sapiens]","3//A2MP1"]
[837,1324,2.41,5.55,1.20345462500751,{"v":2.66319558888557e-05,"d":"2.66E-05"},"Up",{"v":5.58014e-06,"d":"5.58E-06"},"CASP4","GO:0005783//endoplasmic reticulum;GO:0072557//IPAF inflammasome complex;GO:0072559//NLRP3 inflammasome complex;GO:0043234//protein complex;GO:0005829//cytosol;GO:0005576//extracellular region;GO:0005789//endoplasmic reticulum membrane;GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0097169//AIM2 inflammasome complex","GO:0050700//CARD domain binding;GO:0097153//cysteine-type endopeptidase activity involved in apoptotic process;GO:0004197//cysteine-type endopeptidase activity","GO:1903265//positive regulation of tumor necrosis factor-mediated signaling pathway;GO:1904646//cellular response to amyloid-beta;GO:0006954//inflammatory response;GO:0006915//apoptotic process;GO:0050727//regulation of inflammatory response;GO:0006508//proteolysis;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0097193//intrinsic apoptotic signaling pathway;GO:0045087//innate immune response;GO:0042981//regulation of apoptotic process","K04394//caspase 4 [EC:3.4.22.57 3.4.22.64]","NP_001216.1//caspase-4 isoform alpha precursor [Homo sapiens]","3//A2MP1;2//1"]
[84226,6218,0.1,0.23,1.20163386116965,0.108839896648192,"*",0.0516332,"C2orf16","GO:0070062//extracellular exosome;GO:0005634//nucleus","NA","NA","K20093//DNA excision repair protein ERCC-6-like [EC:3.6.4.12];K13172//serine/arginine repetitive matrix protein 2","NP_115642.3//uncharacterized protein C2orf16 [Homo sapiens]","3//A2MP1"]
[397,1279,0.2,0.46,1.20163386116965,0.364401922041106,"*",0.225316,"ARHGDIB","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005856//cytoskeleton;GO:0005829//cytosol;GO:0031410//cytoplasmic vesicle;GO:0005737//cytoplasm","GO:0005094//Rho GDP-dissociation inhibitor activity;GO:0048365//Rac GTPase binding;GO:0003924//GTPase activity;GO:0005096//GTPase activator activity","GO:0007162//negative regulation of cell adhesion;GO:2000249//regulation of actin cytoskeleton reorganization;GO:0006928//movement of cell or subcellular component;GO:1901164//negative regulation of trophoblast cell migration;GO:0007275//multicellular organism development;GO:0035023//regulation of Rho protein signal transduction;GO:0071461//cellular response to redox state;GO:0051056//regulation of small GTPase mediated signal transduction","K12462//Rho GDP-dissociation inhibitor","NP_001166.3//rho GDP-dissociation inhibitor 2 [Homo sapiens]","6;1//3"]
[5155,3205,1,2.3,1.20163386116965,0.000711278922537486,"Up",0.0001930258,"PDGFB","GO:0016020//membrane;GO:0031012//extracellular matrix;GO:0005788//endoplasmic reticulum lumen;GO:0016323//basolateral plasma membrane;GO:0005615//extracellular space;GO:0005622//intracellular;GO:0005737//cytoplasm;GO:0009986//cell surface","GO:0005161//platelet-derived growth factor receptor binding;GO:0008083//growth factor activity;GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0048407//platelet-derived growth factor binding;GO:0016176//superoxide-generating NADPH oxidase activator activity;GO:0005518//collagen binding;GO:0042056//chemoattractant activity","GO:1902895//positive regulation of pri-miRNA transcription from RNA polymerase II promoter;GO:0030335//positive regulation of cell migration;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0007596//blood coagulation;GO:0031954//positive regulation of protein autophosphorylation;GO:1904707//positive regulation of vascular smooth muscle cell proliferation;GO:0032091//negative regulation of protein binding;GO:0060326//cell chemotaxis;GO:0071363//cellular response to growth factor stimulus;GO:1904754//positive regulation of vascular associated smooth muscle cell migration;GO:0009611//response to wounding;GO:1905176//positive regulation of vascular smooth muscle cell dedifferentiation;GO:0070528//protein kinase C signaling;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0048146//positive regulation of fibroblast proliferation;GO:0032147//activation of protein kinase activity;GO:0072593//reactive oxygen species metabolic process;GO:0045740//positive regulation of DNA replication;GO:0035655//interleukin-18-mediated signaling pathway;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0072126//positive regulation of glomerular mesangial cell proliferation;GO:0050921//positive regulation of chemotaxis;GO:0018105//peptidyl-serine phosphorylation;GO:1902894//negative regulation of pri-miRNA transcription from RNA polymerase II promoter;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0032148//activation of protein kinase B activity;GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0035793//positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway;GO:0010544//negative regulation of platelet activation;GO:0090280//positive regulation of calcium ion import;GO:0002548//monocyte chemotaxis;GO:0001938//positive regulation of endothelial cell proliferation;GO:0045840//positive regulation of mitotic nuclear division;GO:0018108//peptidyl-tyrosine phosphorylation;GO:1905064//negative regulation of vascular smooth muscle cell differentiation;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0043406//positive regulation of MAP kinase activity;GO:0010512//negative regulation of phosphatidylinositol biosynthetic process;GO:2000573//positive regulation of DNA biosynthetic process;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:1900127//positive regulation of hyaluronan biosynthetic process;GO:0008284//positive regulation of cell proliferation","K17386//platelet-derived growth factor subunit B","XP_019516155.1//PREDICTED: platelet-derived growth factor subunit B isoform X1 [Hipposideros armiger];NP_148937.1//platelet-derived growth factor subunit B isoform 2 [Homo sapiens]","3//A2MP1"]
[8877,1960,4.73,10.86,1.19911201446497,{"v":4.57398727160494E-13,"d":"4.57E-13"},"Up",{"v":3.71096e-14,"d":"3.71E-14"},"SPHK1","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0000287//magnesium ion binding;GO:0003951//NAD+ kinase activity;GO:0003677//DNA binding;GO:0005524//ATP binding;GO:0017050//D-erythro-sphingosine kinase activity;GO:0008481//sphinganine kinase activity;GO:0038036//sphingosine-1-phosphate receptor activity;GO:0005516//calmodulin binding;GO:0051721//protein phosphatase 2A binding","GO:0006670//sphingosine metabolic process;GO:0030335//positive regulation of cell migration;GO:0030307//positive regulation of cell growth;GO:0035556//intracellular signal transduction;GO:0001568//blood vessel development;GO:0010803//regulation of tumor necrosis factor-mediated signaling pathway;GO:0007420//brain development;GO:0032651//regulation of interleukin-1 beta production;GO:0045766//positive regulation of angiogenesis;GO:0006457//protein folding;GO:0007165//signal transduction;GO:0046512//sphingosine biosynthetic process;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0030148//sphingolipid biosynthetic process;GO:0019722//calcium-mediated signaling;GO:0048146//positive regulation of fibroblast proliferation;GO:0045931//positive regulation of mitotic cell cycle;GO:0031398//positive regulation of protein ubiquitination;GO:0043066//negative regulation of apoptotic process;GO:0006954//inflammatory response;GO:0042346//positive regulation of NF-kappaB import into nucleus;GO:0045987//positive regulation of smooth muscle contraction;GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:0046521//sphingoid catabolic process","K04718//sphingosine kinase [EC:2.7.1.91]","XP_008009822.1//PREDICTED: sphingosine kinase 1 isoform X1 [Chlorocebus sabaeus];NP_892010.2//sphingosine kinase 1 isoform 2 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[90853,2571,1.84,4.21,1.19411446700938,{"v":4.10460903798481E-7,"d":"4.10E-07"},"Up",{"v":6.42646e-08,"d":"6.43E-08"},"SPOCD1","NA","NA","GO:0010923//negative regulation of phosphatase activity;GO:0006351//transcription, DNA-templated","K17596//SPOC domain-containing protein 1","NP_001268916.1//SPOC domain-containing protein 1 isoform 2 [Homo sapiens];XP_016858271.1//PREDICTED: SPOC domain-containing protein 1 isoform X4 [Homo sapiens];NP_653170.3//SPOC domain-containing protein 1 isoform 1 [Homo sapiens]","1//3;5"]
[123099,1411,0.35,0.8,1.1926450779424,0.152461624006887,"*",0.0776052,"DEGS2","GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0042284//sphingolipid delta-4 desaturase activity;GO:0000170//sphingosine hydroxylase activity","GO:0006667//sphinganine metabolic process;GO:0030148//sphingolipid biosynthetic process;GO:0046513//ceramide biosynthetic process","K04712//sphingolipid 4-desaturase/C4-monooxygenase [EC:1.14.19.17 1.14.18.5]","XP_001157834.2//PREDICTED: sphingolipid delta(4)-desaturase/C4-monooxygenase DES2 [Pan troglodytes]","2//1"]
[5342,3016,0.28,0.64,1.1926450779424,0.0398970881789137,"*",0.0164169,"PLGLB2","NA","NA","NA","K01315//plasminogen [EC:3.4.21.7]","XP_003820290.1//PREDICTED: plasminogen isoform X1 [Pan paniscus]",4]
[283358,3438,0.07,0.16,1.1926450779424,0.364217545436147,"*",0.225316,"B4GALNT3","GO:0043231//intracellular membrane-bounded organelle;GO:0032580//Golgi cisterna membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane","GO:0033842//N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity;GO:0008376//acetylgalactosaminyltransferase activity","NA","K09656//beta-1,4-N-acetylgalactosaminyltransferase 3 [EC:2.4.1.244]","NP_775864.3//beta-1,4-N-acetylgalactosaminyltransferase 3 [Homo sapiens]","3//A2MP1"]
[25858,764,1.2,2.74,1.19114148735201,0.0470757067223382,"*",0.01976272,"CATSPERZ","GO:0097228//sperm principal piece;GO:0005737//cytoplasm;GO:0036128//CatSper complex","NA","GO:0030317//flagellated sperm motility;GO:0007140//male meiotic nuclear division;GO:0048240//sperm capacitation;GO:0007283//spermatogenesis","K04915//potassium channel subfamily K member 4","NP_001034585.1//cation channel sperm-associated protein subunit zeta [Homo sapiens]","1//3"]
[3269,4298,1.98,4.52,1.19082234233558,{"v":1.03241540269461E-12,"d":"1.03E-12"},"Up",{"v":8.6347e-14,"d":"8.63E-14"},"HRH1","GO:0005887//integral component of plasma membrane;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0004969//histamine receptor activity;GO:0004930//G-protein coupled receptor activity","GO:0008542//visual learning;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway;GO:0048245//eosinophil chemotaxis;GO:0019229//regulation of vasoconstriction;GO:0043114//regulation of vascular permeability;GO:0050804//modulation of chemical synaptic transmission;GO:0006954//inflammatory response;GO:0007613//memory;GO:0045907//positive regulation of vasoconstriction;GO:0048016//inositol phosphate-mediated signaling;GO:0032962//positive regulation of inositol trisphosphate biosynthetic process;GO:0071420//cellular response to histamine;GO:0048167//regulation of synaptic plasticity","K04149//histamine receptor H1","NP_000852.1//histamine H1 receptor [Homo sapiens]","1//3;3//A2MP1"]
[128344,2260,0.25,0.57,1.18903382439002,0.128864676821023,"*",0.0632384,"PIFO","GO:0036064//ciliary basal body;GO:0005634//nucleus;GO:0031410//cytoplasmic vesicle;GO:0005802//trans-Golgi network","GO:0043015//gamma-tubulin binding;GO:0048487//beta-tubulin binding;GO:0008092//cytoskeletal protein binding;GO:0019894//kinesin binding;GO:0017137//Rab GTPase binding;GO:0019901//protein kinase binding","GO:0031344//regulation of cell projection organization;GO:0033674//positive regulation of kinase activity;GO:0030030//cell projection organization","NA","NP_001287760.1//protein pitchfork isoform 2 [Homo sapiens];NP_857594.2//protein pitchfork isoform 1 [Homo sapiens]","1//3;5"]
[2707,1953,0.18,0.41,1.18762700317577,0.150102786873921,"*",0.0761696,"GJB3","GO:0043231//intracellular membrane-bounded organelle;GO:0005921//gap junction;GO:0005922//connexin complex;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0005737//cytoplasm","GO:0005243//gap junction channel activity","GO:0071300//cellular response to retinoic acid;GO:0043588//skin development;GO:0007154//cell communication;GO:0001890//placenta development;GO:0001701//in utero embryonic development;GO:0007283//spermatogenesis","K07622//gap junction beta-3 protein","NP_076872.1//gap junction beta-3 protein [Homo sapiens]","1//3;2//1"]
[6772,4117,41.1,93.57,1.18690765952626,{"v":5.98636708923077e-220,"d":"5.99E-220"},"Up",{"v":9.74368e-223,"d":"9.74E-223"},"STAT1","GO:0030425//dendrite;GO:0030424//axon;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0000983//transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding;GO:0003690//double-stranded DNA binding;GO:0045296//cadherin binding;GO:0004871//signal transducer activity;GO:0019899//enzyme binding;GO:0003700//DNA binding transcription factor activity;GO:0001047//core promoter binding","GO:0007259//JAK-STAT cascade;GO:0034097//response to cytokine;GO:0072308//negative regulation of metanephric nephron tubule epithelial cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0071346//cellular response to interferon-gamma;GO:0035458//cellular response to interferon-beta;GO:0007584//response to nutrient;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0072136//metanephric mesenchymal cell proliferation involved in metanephros development;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0001937//negative regulation of endothelial cell proliferation;GO:0016525//negative regulation of angiogenesis;GO:0043434//response to peptide hormone;GO:0051591//response to cAMP;GO:0006351//transcription, DNA-templated;GO:0006915//apoptotic process;GO:0032869//cellular response to insulin stimulus;GO:0008015//blood circulation;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0072162//metanephric mesenchymal cell differentiation;GO:0008284//positive regulation of cell proliferation","K11220//signal transducer and activator of transcription 1","CAH18430.1//hypothetical protein [Homo sapiens];NP_009330.1//signal transducer and activator of transcription 1-alpha/beta isoform alpha [Homo sapiens]","3//A2MP1;2//1"]
[348938,3240,4.08,9.28,1.18555565315608,{"v":5.57631840677966e-19,"d":"5.58E-19"},"Up",{"v":2.88346e-20,"d":"2.88E-20"},"NIPAL4","NA","NA","NA","K19364//magnesium transporter NIPA1","XP_014200623.1//PREDICTED: magnesium transporter NIPA4 [Pan paniscus]","1//3"]
[722,2256,0.11,0.25,1.18442457113743,0.364291273684211,"*",0.225316,"C4BPA","GO:0005615//extracellular space;GO:0072562//blood microparticle;GO:0044216//other organism cell;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0003723//RNA binding","GO:0006958//complement activation, classical pathway;GO:0030449//regulation of complement activation;GO:0045732//positive regulation of protein catabolic process;GO:0045959//negative regulation of complement activation, classical pathway;GO:1903027//regulation of opsonization;GO:0045087//innate immune response","K04002//complement component 4 binding protein, alpha","NP_000706.1//C4b-binding protein alpha chain precursor [Homo sapiens]","3//A2MP1"]
[100134938,1360,5.36,12.17,1.18302426225596,{"v":1.33403176594427E-10,"d":"1.33E-10"},"Up",{"v":1.34873E-11,"d":"1.35E-11"},"UPK3BL1","NA","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K06245//laminin, beta 4;K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K17630//Ras GTPase-activating protein 4;K12025//tripartite motif-containing protein 52","XP_016868384.1//PREDICTED: uroplakin-3b-like protein isoform X1 [Homo sapiens]","2//1"]
[163732,1312,30.45,69.13,1.18286969751349,{"v":2.102865282e-54,"d":"2.10E-54"},"Up",{"v":2.63286e-56,"d":"2.63E-56"},"CITED4","NA","NA","NA","K21361//Cbp/p300-interacting transactivator 2","XP_021527780.1//LOW QUALITY PROTEIN: cbp/p300-interacting transactivator 4 [Aotus nancymaae]","2//1"]
[5273,2128,0.19,0.43,1.17833724125851,0.15015835991608,"*",0.0761696,"SERPINB10","NA","NA","NA","K13963//serpin B","XP_009250730.1//PREDICTED: serpin B10 [Pongo abelii]","2//1"]
[241,921,0.99,2.24,1.17799830197799,0.0470686878306247,"*",0.01976272,"ALOX5AP","GO:0016020//membrane;GO:0031965//nuclear membrane;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005635//nuclear envelope;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0004051//arachidonate 5-lipoxygenase activity;GO:0047485//protein N-terminus binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0019899//enzyme binding;GO:0008047//enzyme activator activity;GO:0050544//arachidonic acid binding","GO:0002675//positive regulation of acute inflammatory response;GO:0019370//leukotriene biosynthetic process;GO:0006691//leukotriene metabolic process;GO:0002540//leukotriene production involved in inflammatory response;GO:0071277//cellular response to calcium ion;GO:2001300//lipoxin metabolic process;GO:0019372//lipoxygenase pathway;GO:0070207//protein homotrimerization","K20735//arachidonate 5-lipoxygenase-activating protein","NP_001191335.1//arachidonate 5-lipoxygenase-activating protein isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[162993,2054,0.23,0.52,1.17687776208408,0.44747188010085,"*",0.299986,"ZNF846","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","XP_017194262.1//PREDICTED: uncharacterized protein LOC100349966 [Oryctolagus cuniculus];XP_009191705.2//zinc finger protein 846 isoform X2 [Papio anubis];XP_010591673.1//PREDICTED: zinc finger protein 14-like [Loxodonta africana]","1//3;2//1"]
[11054,2445,22.49,50.79,1.17526081283898,{"v":6.77384730909091e-75,"d":"6.77E-75"},"Up",{"v":5.59752E-77,"d":"5.60E-77"},"OGFR","GO:0016020//membrane;GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0004985//opioid receptor activity","GO:0001558//regulation of cell growth","K06568//mucin-1","NP_031372.2//opioid growth factor receptor [Homo sapiens]","3//A2MP1"]
[51561,1049,0.31,0.7,1.17508670655809,0.303528119940349,"*",0.178385,"IL23A","GO:0005788//endoplasmic reticulum lumen;GO:0005576//extracellular region;GO:0070743//interleukin-23 complex","GO:0045519//interleukin-23 receptor binding;GO:0005125//cytokine activity","GO:0042102//positive regulation of T cell proliferation;GO:0032740//positive regulation of interleukin-17 production;GO:0042509//regulation of tyrosine phosphorylation of STAT protein;GO:0045672//positive regulation of osteoclast differentiation;GO:2000330//positive regulation of T-helper 17 cell lineage commitment;GO:0032760//positive regulation of tumor necrosis factor production;GO:0032816//positive regulation of natural killer cell activation;GO:0002827//positive regulation of T-helper 1 type immune response;GO:0045087//innate immune response;GO:0032729//positive regulation of interferon-gamma production;GO:0042104//positive regulation of activated T cell proliferation;GO:0010536//positive regulation of activation of Janus kinase activity;GO:2000318//positive regulation of T-helper 17 type immune response;GO:0032725//positive regulation of granulocyte macrophage colony-stimulating factor production;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0048771//tissue remodeling;GO:0032733//positive regulation of interleukin-10 production;GO:0050829//defense response to Gram-negative bacterium;GO:0032693//negative regulation of interleukin-10 production;GO:0051135//positive regulation of NK T cell activation;GO:0034105//positive regulation of tissue remodeling;GO:0050729//positive regulation of inflammatory response;GO:0032819//positive regulation of natural killer cell proliferation;GO:0043382//positive regulation of memory T cell differentiation;GO:0032735//positive regulation of interleukin-12 production;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0035722//interleukin-12-mediated signaling pathway;GO:0090023//positive regulation of neutrophil chemotaxis;GO:0051607//defense response to virus;GO:0006954//inflammatory response;GO:0042346//positive regulation of NF-kappaB import into nucleus;GO:0051142//positive regulation of NK T cell proliferation;GO:0042098//T cell proliferation;GO:0006955//immune response;GO:0002230//positive regulation of defense response to virus by host","K05426//interleukin 23, alpha subunit p19","NP_057668.1//interleukin-23 subunit alpha precursor [Homo sapiens]","2//1"]
[948,2800,0.04,0.09,1.16992500144231,0.434273696958247,"*",0.287794,"CD36","GO:0005615//extracellular space;GO:0009897//external side of plasma membrane;GO:0016324//apical plasma membrane;GO:0030666//endocytic vesicle membrane;GO:0031526//brush border membrane;GO:0009986//cell surface;GO:0045121//membrane raft;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0045177//apical part of cell;GO:0005581//collagen trimer","GO:0008289//lipid binding;GO:0005041//low-density lipoprotein receptor activity;GO:0001540//amyloid-beta binding;GO:0071813//lipoprotein particle binding;GO:0030169//low-density lipoprotein particle binding;GO:0070892//lipoteichoic acid receptor activity;GO:0008035//high-density lipoprotein particle binding","GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0010744//positive regulation of macrophage derived foam cell differentiation;GO:0060100//positive regulation of phagocytosis, engulfment;GO:0007596//blood coagulation;GO:0070543//response to linoleic acid;GO:0031623//receptor internalization;GO:0071222//cellular response to lipopolysaccharide;GO:2000334//positive regulation of blood microparticle formation;GO:0007166//cell surface receptor signaling pathway;GO:0032760//positive regulation of tumor necrosis factor production;GO:0071221//cellular response to bacterial lipopeptide;GO:0010886//positive regulation of cholesterol storage;GO:0050909//sensory perception of taste;GO:0034197//triglyceride transport;GO:0010628//positive regulation of gene expression;GO:0043277//apoptotic cell clearance;GO:2000121//regulation of removal of superoxide radicals;GO:0044130//negative regulation of growth of symbiont in host;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0030299//intestinal cholesterol absorption;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0030194//positive regulation of blood coagulation;GO:0050702//interleukin-1 beta secretion;GO:0032755//positive regulation of interleukin-6 production;GO:0071447//cellular response to hydroperoxide;GO:0006910//phagocytosis, recognition;GO:0042992//negative regulation of transcription factor import into nucleus;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0032735//positive regulation of interleukin-12 production;GO:1900227//positive regulation of NLRP3 inflammasome complex assembly;GO:1990000//amyloid fibril formation;GO:0070508//cholesterol import;GO:0050830//defense response to Gram-positive bacterium;GO:0042953//lipoprotein transport;GO:0060907//positive regulation of macrophage cytokine production;GO:0044539//long-chain fatty acid import;GO:0034383//low-density lipoprotein particle clearance;GO:0035634//response to stilbenoid;GO:0071223//cellular response to lipoteichoic acid;GO:0055096//low-density lipoprotein particle mediated signaling;GO:1904646//cellular response to amyloid-beta;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0019915//lipid storage;GO:0006955//immune response;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:2000505//regulation of energy homeostasis","K06259//CD36 antigen","NP_001276838.1//platelet glycoprotein 4 isoform 3 [Homo sapiens];NP_001001547.1//platelet glycoprotein 4 isoform 1 [Homo sapiens];NP_001276837.1//platelet glycoprotein 4 isoform 2 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[116449,5602,0.08,0.18,1.16992500144231,0.18187033614889,"*",0.0954324,"CLNK","GO:0005622//intracellular","GO:0005070//SH3/SH2 adaptor activity","GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0006955//immune response;GO:0035556//intracellular signal transduction","K07361//lymphocyte cytosolic protein 2","XP_011512077.1//PREDICTED: cytokine-dependent hematopoietic cell linker isoform X1 [Homo sapiens]","3//A2MP1"]
[7161,5140,0.08,0.18,1.16992500144231,0.251376765867138,"*",0.1423692,"TP73","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000785//chromatin;GO:0030054//cell junction;GO:0005737//cytoplasm;GO:0005667//transcription factor complex;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0005739//mitochondrion","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0002039//p53 binding;GO:0042802//identical protein binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0019901//protein kinase binding;GO:0046872//metal ion binding;GO:0003684//damaged DNA binding;GO:0003682//chromatin binding;GO:0043565//sequence-specific DNA binding;GO:0008134//transcription factor binding;GO:0003700//DNA binding transcription factor activity;GO:0097371//MDM2/MDM4 family protein binding","GO:0060044//negative regulation of cardiac muscle cell proliferation;GO:0007346//regulation of mitotic cell cycle;GO:0048714//positive regulation of oligodendrocyte differentiation;GO:0010332//response to gamma radiation;GO:0034644//cellular response to UV;GO:0043065//positive regulation of apoptotic process;GO:0008285//negative regulation of cell proliferation;GO:0042493//response to drug;GO:1900740//positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway;GO:0043524//negative regulation of neuron apoptotic process;GO:0051262//protein tetramerization;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0016032//viral process;GO:0006915//apoptotic process;GO:1901796//regulation of signal transduction by p53 class mediator;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:1902036//regulation of hematopoietic stem cell differentiation;GO:0031571//mitotic G1 DNA damage checkpoint;GO:0010468//regulation of gene expression;GO:0001822//kidney development;GO:0007050//cell cycle arrest;GO:0043508//negative regulation of JUN kinase activity;GO:0045893//positive regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006974//cellular response to DNA damage stimulus;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0000187//activation of MAPK activity;GO:0010243//response to organonitrogen compound;GO:0010165//response to X-ray;GO:0006298//mismatch repair;GO:0006351//transcription, DNA-templated;GO:0045665//negative regulation of neuron differentiation;GO:0071158//positive regulation of cell cycle arrest;GO:0042981//regulation of apoptotic process;GO:0006978//DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator","K10148//tumor protein p73","NP_005418.1//tumor protein p73 isoform a [Homo sapiens];NP_001191115.1//tumor protein p73 isoform j [Homo sapiens];NP_001191117.1//tumor protein p73 isoform l [Homo sapiens];NP_001119713.1//tumor protein p73 isoform c [Homo sapiens];NP_001191113.1//tumor protein p73 isoform h [Homo sapiens];XP_008572777.1//PREDICTED: tumor protein p73 isoform X1 [Galeopterus variegatus];NP_001191120.1//tumor protein p73 isoform g [Homo sapiens];NP_001191119.1//tumor protein p73 isoform f [Homo sapiens];XP_007979055.1//PREDICTED: tumor protein p73 isoform X7 [Chlorocebus sabaeus];NP_001191116.1//tumor protein p73 isoform k [Homo sapiens];NP_001119712.1//tumor protein p73 isoform b [Homo sapiens]","1//3;3//A2MP1;2//1"]
[80757,1551,6.26,14.08,1.16941277170468,{"v":2.01164718693227E-13,"d":"2.01E-13"},"Up",{"v":1.580454e-14,"d":"1.58E-14"},"TMEM121","GO:0016021//integral component of membrane","NA","NA","K16628//collagen, type VII, alpha;K11253//histone H3","NP_079544.1//transmembrane protein 121 [Homo sapiens]","1//3;3//A2MP1"]
[55509,992,9.63,21.51,1.1593998215796,{"v":8.58707829691032e-13,"d":"8.59E-13"},"Up",{"v":7.1335e-14,"d":"7.13E-14"},"BATF3","GO:0005634//nucleus","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003714//transcription corepressor activity;GO:0003700//DNA binding transcription factor activity;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0097028//dendritic cell differentiation;GO:0009615//response to virus;GO:0043011//myeloid dendritic cell differentiation;GO:0006366//transcription from RNA polymerase II promoter","K09034//ATF-like basic leucine zipper transcriptional factor","NP_061134.1//basic leucine zipper transcriptional factor ATF-like 3 [Homo sapiens]","2//1"]
[200879,2478,3.64,8.12,1.15754127698648,{"v":1.92427701138686e-12,"d":"1.92E-12"},"Up",{"v":1.650344e-13,"d":"1.65E-13"},"LIPH","GO:0005615//extracellular space;GO:0005886//plasma membrane","GO:0004620//phospholipase activity;GO:0052689//carboxylic ester hydrolase activity;GO:0008201//heparin binding","GO:0016042//lipid catabolic process;GO:0006654//phosphatidic acid biosynthetic process","K19404//phosphatidic acid-selective&#160;phospholipase A1 [EC:3.1.1.-]","NP_640341.1//lipase member H precursor [Homo sapiens]","2//1"]
[83854,1779,1.36,3.03,1.15571114222261,4.12433834849952E-4,"Up",1.066844E-4,"ANGPTL6","GO:0070062//extracellular exosome;GO:0030141//secretory granule","NA","NA","K05467//angiopoietin 4","XP_005260148.1//PREDICTED: angiopoietin-related protein 6 isoform X2 [Homo sapiens];XP_011526650.1//PREDICTED: angiopoietin-related protein 6 isoform X3 [Homo sapiens]","1//3;2//1"]
[834,1481,0.09,0.2,1.15200309344505,0.529759689468548,"*",0.37379,"CASP1","GO:0072557//IPAF inflammasome complex;GO:0072559//NLRP3 inflammasome complex;GO:0097179//protease inhibitor complex;GO:0043234//protein complex;GO:0005829//cytosol;GO:0072558//NLRP1 inflammasome complex;GO:0005576//extracellular region;GO:0005739//mitochondrion;GO:0097169//AIM2 inflammasome complex","GO:0004175//endopeptidase activity;GO:0050700//CARD domain binding;GO:0097153//cysteine-type endopeptidase activity involved in apoptotic process;GO:0042802//identical protein binding;GO:0004197//cysteine-type endopeptidase activity;GO:0008656//cysteine-type endopeptidase activator activity involved in apoptotic process;GO:0019900//kinase binding","GO:0033198//response to ATP;GO:0071260//cellular response to mechanical stimulus;GO:0051882//mitochondrial depolarization;GO:0071222//cellular response to lipopolysaccharide;GO:0032611//interleukin-1 beta production;GO:0071310//cellular response to organic substance;GO:0071346//cellular response to interferon-gamma;GO:1901998//toxin transport;GO:0097300//programmed necrotic cell death;GO:0010506//regulation of autophagy;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0016540//protein autoprocessing;GO:0070269//pyroptosis;GO:0007165//signal transduction;GO:0050718//positive regulation of interleukin-1 beta secretion;GO:0050717//positive regulation of interleukin-1 alpha secretion;GO:1903265//positive regulation of tumor necrosis factor-mediated signaling pathway;GO:0001666//response to hypoxia;GO:0006915//apoptotic process;GO:0060081//membrane hyperpolarization;GO:0050727//regulation of inflammatory response;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0006508//proteolysis;GO:0042981//regulation of apoptotic process","K01370//caspase 1 [EC:3.4.22.36]","XP_018893204.1//PREDICTED: caspase-1 isoform X1 [Gorilla gorilla gorilla];NP_150637.1//caspase-1 isoform epsilon [Homo sapiens];NP_150635.1//caspase-1 isoform gamma [Homo sapiens];NP_150636.1//caspase-1 isoform delta [Homo sapiens]","4;3//A2MP1;2//1"]
[285346,1970,0.09,0.2,1.15200309344505,0.433863850132125,"*",0.287794,"ZNF852","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_011737277.1//PREDICTED: zinc finger protein with KRAB and SCAN domains 7 isoform X3 [Macaca nemestrina]","1//3"]
[10485,802,0.33,0.73,1.14543043952156,0.364512637634191,"*",0.225316,"C1orf61","GO:0005634//nucleus","NA","GO:0045944//positive regulation of transcription from RNA polymerase II promoter","NA","NP_001307383.1//protein CROC-4 isoform 3 [Homo sapiens];NP_006356.1//protein CROC-4 isoform 1 [Homo sapiens];XP_017803429.1//uncharacterized protein LOC101005783 isoform X4 [Papio anubis];NP_001307384.1//protein CROC-4 isoform 4 [Homo sapiens]","1//3;2//1"]
[65249,4339,2.39,5.27,1.14079234365647,{"v":7.27083014930271e-14,"d":"7.27E-14"},"Up",{"v":5.54848e-15,"d":"5.55E-15"},"ZSWIM4","NA","GO:0008270//zinc ion binding","NA","K16628//collagen, type VII, alpha;K01231//alpha-mannosidase II [EC:3.2.1.114]","NP_075560.2//zinc finger SWIM domain-containing protein 4 [Homo sapiens]","2//1"]
[100287036,1443,0.79,1.74,1.13916274767163,0.0284454637110436,"*",0.01114206,"LOC100287036","NA","NA","NA","NA","XP_011916790.1//PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein LOC105586224, partial [Cercocebus atys]","2//1"]
[163175,2906,0.05,0.11,1.13750352374993,0.609503803616698,"*",0.451538,"LGI4","GO:0005615//extracellular space;GO:0005576//extracellular region","NA","GO:0031641//regulation of myelination;GO:0014009//glial cell proliferation;GO:0008344//adult locomotory behavior;GO:0042551//neuron maturation;GO:0022011//myelination in peripheral nervous system","K19999//leucine-rich repeat LGI family member 3","NP_644813.1//leucine-rich repeat LGI family member 4 precursor [Homo sapiens]","2//1"]
[23630,1487,0.05,0.11,1.13750352374993,0.73580230124843,"*",0.623548,"KCNE5","GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex","GO:0005249//voltage-gated potassium channel activity;GO:0044325//ion channel binding;GO:0015459//potassium channel regulator activity;GO:0086008//voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization","GO:0086005//ventricular cardiac muscle cell action potential;GO:0086013//membrane repolarization during cardiac muscle cell action potential;GO:1901381//positive regulation of potassium ion transmembrane transport;GO:1901380//negative regulation of potassium ion transmembrane transport;GO:0086091//regulation of heart rate by cardiac conduction;GO:1901379//regulation of potassium ion transmembrane transport;GO:2001257//regulation of cation channel activity;GO:0060306//regulation of membrane repolarization;GO:0008016//regulation of heart contraction;GO:0086014//atrial cardiac muscle cell action potential;GO:0060048//cardiac muscle contraction;GO:0060372//regulation of atrial cardiac muscle cell membrane repolarization;GO:0071435//potassium ion export;GO:0071805//potassium ion transmembrane transport;GO:0060307//regulation of ventricular cardiac muscle cell membrane repolarization","K04895//potassium voltage-gated channel Isk-related subfamily E member 1-like","NP_036414.1//potassium voltage-gated channel subfamily E regulatory beta subunit 5 [Homo sapiens]","3//A2MP1"]
[165186,3399,0.05,0.11,1.13750352374993,0.608989193853428,"*",0.451538,"TOGARAM2","NA","NA","NA","K22020//mucin-19","NP_001308468.1//TOG array regulator of axonemal microtubules protein 2 isoform 3 [Homo sapiens];XP_018877121.1//PREDICTED: protein FAM179A [Gorilla gorilla gorilla];NP_001308467.1//TOG array regulator of axonemal microtubules protein 2 isoform 2 [Homo sapiens]","1//3;2//1"]
[283514,4005,0.05,0.11,1.13750352374993,0.433986722930237,"*",0.287794,"SIAH3","NA","NA","NA","K02184//formin 2","XP_012638173.1//seven in absentia homolog 3 [Microcebus murinus]","2//1"]
[23414,4507,0.05,0.11,1.13750352374993,0.495712655178669,"*",0.342164,"ZFPM2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0001105//RNA polymerase II transcription coactivator activity;GO:0001085//RNA polymerase II transcription factor binding;GO:0003676//nucleic acid binding;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0008270//zinc ion binding;GO:0008134//transcription factor binding","GO:0003148//outflow tract septum morphogenesis;GO:0030324//lung development;GO:0060412//ventricular septum morphogenesis;GO:0007596//blood coagulation;GO:0006355//regulation of transcription, DNA-templated;GO:2000020//positive regulation of male gonad development;GO:0048568//embryonic organ development;GO:0001570//vasculogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0003221//right ventricular cardiac muscle tissue morphogenesis;GO:0006351//transcription, DNA-templated;GO:0001701//in utero embryonic development;GO:0045599//negative regulation of fat cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:2000195//negative regulation of female gonad development;GO:0060548//negative regulation of cell death;GO:0007506//gonadal mesoderm development","K17442//zinc finger protein ZFPM2","NP_036214.2//zinc finger protein ZFPM2 [Homo sapiens]","3//A2MP1"]
[168455,6827,3.87,8.5,1.13512927488065,{"v":7.8308562855615e-34,"d":"7.83E-34"},"Up",{"v":1.833442E-35,"d":"1.83E-35"},"CCDC71L","NA","NA","GO:0044255//cellular lipid metabolic process;GO:0045600//positive regulation of fat cell differentiation","K06237//collagen, type IV, alpha;K13172//serine/arginine repetitive matrix protein 2","NP_787080.2//coiled-coil domain-containing protein 71L [Homo sapiens]",5]
[10158,894,3.8,8.34,1.13404796511372,{"v":6.81022934747418e-05,"d":"6.81E-05"},"Up",{"v":1.527548e-05,"d":"1.53E-05"},"PDZK1IP1","NA","NA","NA","NA","XP_003921637.2//PREDICTED: PDZK1-interacting protein 1 [Saimiri boliviensis boliviensis]","3//A2MP1"]
[2537,844,6.67,14.63,1.1331711029539,{"v":1.53061075E-7,"d":"1.53E-07"},"Up",{"v":2.25366E-8,"d":"2.25E-08"},"IFI6","GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005886//plasma membrane","NA","GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0060337//type I interferon signaling pathway;GO:0051902//negative regulation of mitochondrial depolarization;GO:0006955//immune response;GO:0001836//release of cytochrome c from mitochondria","NA","XP_012353995.1//PREDICTED: interferon alpha-inducible protein 6 isoform X3 [Nomascus leucogenys];XP_012353994.1//PREDICTED: interferon alpha-inducible protein 6 isoform X2 [Nomascus leucogenys];XP_012353996.1//PREDICTED: interferon alpha-inducible protein 6 isoform X4 [Nomascus leucogenys]","3//A2MP1;2//1"]
[400581,1313,0.62,1.35,1.12261928666396,0.105005540093023,"*",0.0494658,"GRAPL","NA","NA","NA","K04364//growth factor receptor-binding protein 2","XP_002747899.2//PREDICTED: GRB2-related adapter protein [Callithrix jacchus]","1//3;2//1"]
[256126,946,0.52,1.13,1.1197392442741,0.211431989764965,"*",0.1143194,"SYCE2","GO:0005634//nucleus;GO:0000801//central element","NA","GO:0007130//synaptonemal complex assembly;GO:0051301//cell division","K19535//synaptonemal complex central element protein 2","NP_001099048.1//synaptonemal complex central element protein 2 [Homo sapiens]","1//3"]
[3356,4702,0.06,0.13,1.11547721741994,0.364475724962025,"*",0.225316,"HTR2A","GO:0043198//dendritic shaft;GO:0030424//axon;GO:0005901//caveola;GO:0005887//integral component of plasma membrane;GO:0005829//cytosol;GO:0031410//cytoplasmic vesicle;GO:0070852//cell body fiber;GO:0005622//intracellular;GO:0005886//plasma membrane;GO:0043025//neuronal cell body","GO:0051378//serotonin binding;GO:0004993//G-protein coupled serotonin receptor activity;GO:0001965//G-protein alpha-subunit binding;GO:0008144//drug binding;GO:0001618//virus receptor activity;GO:0032403//protein complex binding;GO:0030594//neurotransmitter receptor activity;GO:0071886//1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding","GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0043267//negative regulation of potassium ion transport;GO:0050795//regulation of behavior;GO:0014059//regulation of dopamine secretion;GO:0045821//positive regulation of glycolytic process;GO:0007208//phospholipase C-activating serotonin receptor signaling pathway;GO:0051967//negative regulation of synaptic transmission, glutamatergic;GO:0007610//behavior;GO:0042493//response to drug;GO:0045600//positive regulation of fat cell differentiation;GO:0014832//urinary bladder smooth muscle contraction;GO:0007202//activation of phospholipase C activity;GO:0033674//positive regulation of kinase activity;GO:0014824//artery smooth muscle contraction;GO:0051209//release of sequestered calcium ion into cytosol;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0001659//temperature homeostasis;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0007210//serotonin receptor signaling pathway;GO:0045907//positive regulation of vasoconstriction;GO:0006874//cellular calcium ion homeostasis;GO:0050965//detection of temperature stimulus involved in sensory perception of pain;GO:0048148//behavioral response to cocaine;GO:0043406//positive regulation of MAP kinase activity;GO:0010513//positive regulation of phosphatidylinositol biosynthetic process;GO:0044380//protein localization to cytoskeleton;GO:0046883//regulation of hormone secretion;GO:0006939//smooth muscle contraction;GO:0008219//cell death;GO:0007568//aging;GO:0007613//memory;GO:0007268//chemical synaptic transmission;GO:0050966//detection of mechanical stimulus involved in sensory perception of pain;GO:0030431//sleep;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0008284//positive regulation of cell proliferation","K04157//5-hydroxytryptamine receptor 2","NP_000612.1//5-hydroxytryptamine receptor 2A isoform 1 [Homo sapiens];XP_008050943.2//5-hydroxytryptamine receptor 2A isoform X2 [Carlito syrichta]","4;2//1"]
[339541,1698,0.24,0.52,1.11547721741994,0.251432349452736,"*",0.1423692,"C1orf228","NA","NA","NA","K03575//A/G-specific adenine glycosylase [EC:3.2.2.-]","NP_001139108.1//uncharacterized protein C1orf228 [Homo sapiens]","1//3"]
[9111,1501,8.25,17.85,1.11345804978328,{"v":3.55338875862069e-15,"d":"3.55E-15"},"Up",{"v":2.45138e-16,"d":"2.45E-16"},"NMI","GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0042802//identical protein binding;GO:0003712//transcription cofactor activity","GO:0045824//negative regulation of innate immune response;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0007259//JAK-STAT cascade;GO:0006366//transcription from RNA polymerase II promoter;GO:0006954//inflammatory response;GO:0045355//negative regulation of interferon-alpha biosynthetic process;GO:1902524//positive regulation of protein K48-linked ubiquitination;GO:0045358//negative regulation of interferon-beta biosynthetic process","K15261//poly [ADP-ribose] polymerase 10/14/15 [EC:2.4.2.30]","XP_526097.3//PREDICTED: N-myc-interactor isoform X1 [Pan troglodytes]","2//1"]
[80323,4033,1.24,2.68,1.1118928800709,{"v":7.40708718952234e-07,"d":"7.41E-07"},"Up",{"v":1.203756E-7,"d":"1.20E-07"},"CCDC68","NA","NA","NA","K22031//myocardial zonula adherens protein","NP_079490.1//coiled-coil domain-containing protein 68 [Homo sapiens]","1//3;2//1"]
[56829,5046,17.91,38.4,1.10034097362256,{"v":4.65204255278688E-144,"d":"4.65E-144"},"Up",{"v":1.776478e-146,"d":"1.78E-146"},"ZC3HAV1","NA","GO:0046872//metal ion binding;GO:0003950//NAD+ ADP-ribosyltransferase activity","NA","K15259//poly [ADP-ribose] polymerase 7/11/12/13 [EC:2.4.2.30]","CAE11868.1//hypothetical protein [Homo sapiens]","3//A2MP1"]
[160492,2504,0.21,0.45,1.09953567355091,0.15248037697417,"*",0.0776052,"LMNTD1","GO:0005635//nuclear envelope;GO:0005882//intermediate filament;GO:0005737//cytoplasm","GO:0005198//structural molecule activity","GO:0008283//cell proliferation","K12581//CCR4-NOT transcription complex subunit 7/8;K06245//laminin, beta 4;K07611//lamin B;K02927//large subunit ribosomal protein L40e;K17985//activating molecule in BECN1-regulated autophagy protein 1;K12641//lamin A/C","NP_001139201.1//lamin tail domain-containing protein 1 isoform 4 [Homo sapiens];NP_001139200.1//lamin tail domain-containing protein 1 isoform 1 [Homo sapiens];NP_001139199.1//lamin tail domain-containing protein 1 isoform 3 [Homo sapiens];NP_689803.2//lamin tail domain-containing protein 1 isoform 2 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[730,5964,0.21,0.45,1.09953567355091,0.0370074899123212,"*",0.01506108,"C7","GO:0070062//extracellular exosome;GO:0005579//membrane attack complex;GO:0005576//extracellular region","NA","GO:0006958//complement activation, classical pathway;GO:0030449//regulation of complement activation;GO:0006956//complement activation;GO:0019835//cytolysis;GO:0006955//immune response;GO:0006957//complement activation, alternative pathway;GO:0006883//cellular sodium ion homeostasis","K03996//complement component 7","NP_000578.2//complement component C7 precursor [Homo sapiens]","3//A2MP1"]
[5655,2997,0.14,0.3,1.09953567355091,0.251404554587663,"*",0.1423692,"KLK10","GO:0005576//extracellular region","GO:0004252//serine-type endopeptidase activity;GO:0008236//serine-type peptidase activity","GO:0007049//cell cycle","K09619//kallikrein 10 [EC:3.4.21.-]","NP_002767.2//kallikrein-10 preproprotein [Homo sapiens];XP_007995926.1//PREDICTED: kallikrein-10 isoform X4 [Chlorocebus sabaeus]","1//3;4;2//1"]
[650,3191,0.35,0.75,1.09953567355091,0.0385909874224599,"*",0.01581182,"BMP2","GO:0043231//intracellular membrane-bounded organelle;GO:0005615//extracellular space;GO:0009986//cell surface;GO:0005576//extracellular region;GO:0070724//BMP receptor complex","GO:0008083//growth factor activity;GO:0005125//cytokine activity;GO:0019211//phosphatase activator activity;GO:0004745//retinol dehydrogenase activity;GO:0039706//co-receptor binding;GO:0070700//BMP receptor binding","GO:0060129//thyroid-stimulating hormone-secreting cell differentiation;GO:1902895//positive regulation of pri-miRNA transcription from RNA polymerase II promoter;GO:0001649//osteoblast differentiation;GO:0045666//positive regulation of neuron differentiation;GO:0030335//positive regulation of cell migration;GO:0035054//embryonic heart tube anterior/posterior pattern specification;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0003203//endocardial cushion morphogenesis;GO:0008285//negative regulation of cell proliferation;GO:0055007//cardiac muscle cell differentiation;GO:0042482//positive regulation of odontogenesis;GO:0045600//positive regulation of fat cell differentiation;GO:0060804//positive regulation of Wnt signaling pathway by BMP signaling pathway;GO:0030509//BMP signaling pathway;GO:0001666//response to hypoxia;GO:0042475//odontogenesis of dentin-containing tooth;GO:0042487//regulation of odontogenesis of dentin-containing tooth;GO:0060128//corticotropin hormone secreting cell differentiation;GO:0007219//Notch signaling pathway;GO:0003130//BMP signaling pathway involved in heart induction;GO:0033690//positive regulation of osteoblast proliferation;GO:0021978//telencephalon regionalization;GO:0055008//cardiac muscle tissue morphogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0071407//cellular response to organic cyclic compound;GO:0048839//inner ear development;GO:0003181//atrioventricular valve morphogenesis;GO:0031648//protein destabilization;GO:0045165//cell fate commitment;GO:0030282//bone mineralization;GO:0061036//positive regulation of cartilage development;GO:0000187//activation of MAPK activity;GO:0006029//proteoglycan metabolic process;GO:0072138//mesenchymal cell proliferation involved in ureteric bud development;GO:0001701//in utero embryonic development;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0045669//positive regulation of osteoblast differentiation;GO:0006954//inflammatory response;GO:0009887//animal organ morphogenesis;GO:0048711//positive regulation of astrocyte differentiation;GO:0060039//pericardium development","K21283//bone morphogenetic protein 2","NP_001191.1//bone morphogenetic protein 2 preproprotein [Homo sapiens]","3//A2MP1"]
[9242,2075,28.95,61.95,1.09754093415137,{"v":2.92836243287671e-69,"d":"2.93E-69"},"Up",{"v":2.67648e-71,"d":"2.68E-71"},"MSC","GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0003714//transcription corepressor activity;GO:0001206//transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0046983//protein dimerization activity","GO:1990830//cellular response to leukemia inhibitory factor;GO:0060539//diaphragm development;GO:0014707//branchiomeric skeletal muscle development;GO:0060021//palate development;GO:0006366//transcription from RNA polymerase II promoter","K09072//musculin (activated B-cell factor-1)","NP_005089.2//musculin [Homo sapiens]","3//A2MP1"]
[81606,2956,20.1,42.88,1.09310940439148,{"v":2.24852153866667e-68,"d":"2.25E-68"},"Up",{"v":2.11142e-70,"d":"2.11E-70"},"LBH","GO:0005634//nucleus;GO:0005737//cytoplasm","NA","GO:2000103//positive regulation of mammary stem cell proliferation;GO:0010468//regulation of gene expression;GO:1904677//positive regulation of somatic stem cell division;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:2000737//negative regulation of stem cell differentiation;GO:0030193//regulation of blood coagulation;GO:0007275//multicellular organism development;GO:0060644//mammary gland epithelial cell differentiation;GO:1904674//positive regulation of somatic stem cell population maintenance;GO:0033147//negative regulation of intracellular estrogen receptor signaling pathway","NA","AAG23758.1//PP2281 [Homo sapiens]","3//A2MP1"]
[440689,495,0.68,1.45,1.0924462487646,0.255172732386301,"*",0.1450622,"HIST2H2BF","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0000786//nucleosome","GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity","GO:0006334//nucleosome assembly","K11252//histone H2B","XP_012998546.1//PREDICTED: histone H2B type 2-F isoform X1 [Cavia porcellus];XP_004026583.1//PREDICTED: histone H2B type 2-F-like [Gorilla gorilla gorilla]","4;1//3"]
[100505385,2384,5.58,11.89,1.09141168791647,{"v":1.0210111065033e-15,"d":"1.02E-15"},"Up",{"v":6.7816e-17,"d":"6.78E-17"},"IQCJ-SCHIP1","NA","NA","NA","K21125//mucin-5AC","XP_016795461.1//PREDICTED: schwannomin-interacting protein 1 isoform X3 [Pan troglodytes];XP_016795459.1//PREDICTED: schwannomin-interacting protein 1 isoform X1 [Pan troglodytes]","1//3"]
[158866,6030,0.08,0.17,1.08746284125034,0.285745159771231,"*",0.1657694,"ZDHHC15","GO:0070062//extracellular exosome;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane","GO:0016409//palmitoyltransferase activity;GO:0019706//protein-cysteine S-palmitoyltransferase activity","GO:0018345//protein palmitoylation;GO:0045184//establishment of protein localization;GO:0016188//synaptic vesicle maturation","K20028//palmitoyltransferase ZDHHC2/15/20 [EC:2.3.1.225]","XP_008247070.1//PREDICTED: LOW QUALITY PROTEIN: palmitoyltransferase ZDHHC15 [Oryctolagus cuniculus];NP_001139729.1//palmitoyltransferase ZDHHC15 isoform 3 [Homo sapiens]","1//3;2//1"]
[143162,4946,0.08,0.17,1.08746284125034,0.608732214701663,"*",0.451538,"FRMPD2","GO:0005856//cytoskeleton;GO:0016323//basolateral plasma membrane;GO:0005923//bicellular tight junction;GO:0005737//cytoplasm","GO:0005545//1-phosphatidylinositol binding","GO:0070830//bicellular tight junction assembly","K02374//tyrosine-protein phosphatase non-receptor type 13","NP_001018081.3//FERM and PDZ domain-containing protein 2 isoform 3 [Homo sapiens];NP_001305120.1//FERM and PDZ domain-containing protein 2 isoform 5 precursor [Homo sapiens];NP_001035977.2//FERM and PDZ domain-containing protein 2 isoform 4 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[285679,1208,0.42,0.89,1.08341600818764,0.211456472394627,"*",0.1143194,"C5orf60","GO:0016021//integral component of membrane","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K17985//activating molecule in BECN1-regulated autophagy protein 1;K12025//tripartite motif-containing protein 52","NP_001292317.1//putative uncharacterized protein FLJ35723 isoform a [Homo sapiens];NP_001135778.1//putative uncharacterized protein FLJ35723 isoform b [Homo sapiens]","1//3;2//1"]
[135,2555,0.36,0.76,1.07800251200127,0.088002733069685,"*",0.0403984,"ADORA2A","GO:0030425//dendrite;GO:0048786//presynaptic active zone;GO:0098794//postsynapse;GO:0005622//intracellular;GO:0005882//intermediate filament;GO:0030673//axolemma;GO:0014069//postsynaptic density;GO:0043025//neuronal cell body;GO:0012505//endomembrane system;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0099056//integral component of presynaptic membrane;GO:0005886//plasma membrane;GO:0099055//integral component of postsynaptic membrane","GO:0001609//G-protein coupled adenosine receptor activity;GO:0042802//identical protein binding;GO:0051393//alpha-actinin binding;GO:0046982//protein heterodimerization activity;GO:0031802//type 5 metabotropic glutamate receptor binding;GO:0019899//enzyme binding","GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0014049//positive regulation of glutamate secretion;GO:0050728//negative regulation of inflammatory response;GO:0014057//positive regulation of acetylcholine secretion, neurotransmission;GO:0031000//response to caffeine;GO:0043116//negative regulation of vascular permeability;GO:0051968//positive regulation of synaptic transmission, glutamatergic;GO:0030819//positive regulation of cAMP biosynthetic process;GO:0008285//negative regulation of cell proliferation;GO:0040013//negative regulation of locomotion;GO:0042493//response to drug;GO:0043524//negative regulation of neuron apoptotic process;GO:0045938//positive regulation of circadian sleep/wake cycle, sleep;GO:0006915//apoptotic process;GO:2001235//positive regulation of apoptotic signaling pathway;GO:0008015//blood circulation;GO:0007271//synaptic transmission, cholinergic;GO:0001975//response to amphetamine;GO:0032230//positive regulation of synaptic transmission, GABAergic;GO:0035249//synaptic transmission, glutamatergic;GO:0048167//regulation of synaptic plasticity;GO:0046636//negative regulation of alpha-beta T cell activation;GO:0006355//regulation of transcription, DNA-templated;GO:0051924//regulation of calcium ion transport;GO:0048812//neuron projection morphogenesis;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0060079//excitatory postsynaptic potential;GO:0042311//vasodilation;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0060080//inhibitory postsynaptic potential;GO:0042755//eating behavior;GO:0060134//prepulse inhibition;GO:0050714//positive regulation of protein secretion;GO:0006469//negative regulation of protein kinase activity;GO:0007626//locomotory behavior;GO:0035815//positive regulation of renal sodium excretion;GO:0051899//membrane depolarization;GO:0001963//synaptic transmission, dopaminergic;GO:0014061//regulation of norepinephrine secretion;GO:0035810//positive regulation of urine volume;GO:0051881//regulation of mitochondrial membrane potential;GO:0048143//astrocyte activation","K04266//adenosine receptor A2a","NP_000666.2//adenosine receptor A2a [Homo sapiens]","1//3;5"]
[6442,1089,0.68,1.43,1.07240849552805,0.125179909745708,"*",0.0607092,"SGCA","NA","NA","NA","K12565//alpha-sarcoglycan","XP_011523425.2//PREDICTED: alpha-sarcoglycan isoform X4 [Homo sapiens];XP_003817508.2//PREDICTED: alpha-sarcoglycan isoform X2 [Pan paniscus]","3//A2MP1;2//1"]
[2355,4015,40.01,84.03,1.07054385545006,{"v":2.90505686210526e-176,"d":"2.91E-176"},"Up",{"v":6.91074e-179,"d":"6.91E-179"},"FOSL2","GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0003677//DNA binding;GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA binding transcription factor activity","GO:0003334//keratinocyte development;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0048146//positive regulation of fibroblast proliferation;GO:0008219//cell death","K09030//fos-like antigen 2","NP_005244.1//fos-related antigen 2 [Homo sapiens]","3//A2MP1"]
[116729,805,0.1,0.21,1.0703893278914,0.732555398396705,"*",0.623548,"PPP1R27","NA","GO:0019902//phosphatase binding","GO:0010923//negative regulation of phosphatase activity","K17566//protein phosphatase 1 regulatory subunit 27","XP_008011466.1//PREDICTED: protein phosphatase 1 regulatory subunit 27 [Chlorocebus sabaeus]","3//A2MP1"]
[91694,3530,1.73,3.62,1.06521765944648,{"v":2.43351764521452e-07,"d":"2.43E-07"},"Up",{"v":3.69278e-08,"d":"3.69E-08"},"LONRF1","GO:0005829//cytosol;GO:0005622//intracellular","GO:0061630//ubiquitin protein ligase activity;GO:0046872//metal ion binding;GO:0004842//ubiquitin-protein transferase activity;GO:0031624//ubiquitin conjugating enzyme binding","GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0000209//protein polyubiquitination","K12009//tripartite motif-containing protein 27 [EC:2.3.2.27];K19720//collagen, type III, alpha","NP_001316905.1//LON peptidase N-terminal domain and RING finger protein 1 isoform 2 [Homo sapiens];NP_689484.3//LON peptidase N-terminal domain and RING finger protein 1 isoform 1 [Homo sapiens]","4;1//3"]
[7439,2421,0.22,0.46,1.06413033741972,0.176921640537944,"*",0.0922376,"BEST1","GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0034707//chloride channel complex;GO:0005886//plasma membrane","GO:0005229//intracellular calcium activated chloride channel activity;GO:0042802//identical protein binding;GO:0005254//chloride channel activity;GO:0015106//bicarbonate transmembrane transporter activity","GO:0030321//transepithelial chloride transport;GO:0051924//regulation of calcium ion transport;GO:0050908//detection of light stimulus involved in visual perception;GO:0006821//chloride transport;GO:0034220//ion transmembrane transport;GO:0007601//visual perception","K13878//bestrophin-1","XP_011543532.1//PREDICTED: bestrophin-1 isoform X2 [Homo sapiens];XP_018891909.1//PREDICTED: bestrophin-1 isoform X2 [Gorilla gorilla gorilla];XP_012367626.1//PREDICTED: bestrophin-1 [Nomascus leucogenys]","1//3;3//A2MP1"]
[7130,1439,0.11,0.23,1.06413033741972,0.608526787479963,"*",0.451538,"TNFAIP6","GO:1904724//tertiary granule lumen;GO:0005615//extracellular space;GO:1904813//ficolin-1-rich granule lumen;GO:0005576//extracellular region","GO:0005540//hyaluronic acid binding","GO:0007165//signal transduction;GO:0030335//positive regulation of cell migration;GO:0007267//cell-cell signaling;GO:0030728//ovulation;GO:0050728//negative regulation of inflammatory response;GO:0006954//inflammatory response;GO:0007155//cell adhesion;GO:0043312//neutrophil degranulation","K19018//tumor necrosis factor-inducible gene 6 protein","NP_009046.2//tumor necrosis factor-inducible gene 6 protein precursor [Homo sapiens]","3//A2MP1"]
[6850,5022,0.11,0.23,1.06413033741972,0.23681231799687,"*",0.1326232,"SYK","GO:0042101//T cell receptor complex;GO:0005634//nucleus;GO:0019815//B cell receptor complex;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0005829//cytosol;GO:0032009//early phagosome;GO:0005737//cytoplasm","GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005524//ATP binding;GO:0005102//receptor binding;GO:0004716//signal transducer, downstream of receptor, with protein tyrosine kinase activity;GO:0042169//SH2 domain binding;GO:0019901//protein kinase binding;GO:0035325//Toll-like receptor binding;GO:0004674//protein serine/threonine kinase activity;GO:0005178//integrin binding;GO:0001784//phosphotyrosine residue binding;GO:0019902//phosphatase binding","GO:0050850//positive regulation of calcium-mediated signaling;GO:0016477//cell migration;GO:0032481//positive regulation of type I interferon production;GO:0007159//leukocyte cell-cell adhesion;GO:0090237//regulation of arachidonic acid secretion;GO:0031623//receptor internalization;GO:0002283//neutrophil activation involved in immune response;GO:0002092//positive regulation of receptor internalization;GO:0019370//leukotriene biosynthetic process;GO:0010803//regulation of tumor necrosis factor-mediated signaling pathway;GO:0002554//serotonin secretion by platelet;GO:0090330//regulation of platelet aggregation;GO:0045087//innate immune response;GO:0030154//cell differentiation;GO:0001525//angiogenesis;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0045579//positive regulation of B cell differentiation;GO:0046777//protein autophosphorylation;GO:0007257//activation of JUN kinase activity;GO:0002250//adaptive immune response;GO:0018105//peptidyl-serine phosphorylation;GO:0048514//blood vessel morphogenesis;GO:0050764//regulation of phagocytosis;GO:0032928//regulation of superoxide anion generation;GO:1900086//positive regulation of peptidyl-tyrosine autophosphorylation;GO:0071404//cellular response to low-density lipoprotein particle stimulus;GO:0038083//peptidyl-tyrosine autophosphorylation;GO:0046641//positive regulation of alpha-beta T cell proliferation;GO:0035556//intracellular signal transduction;GO:0042742//defense response to bacterium;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0045401//positive regulation of interleukin-3 biosynthetic process;GO:0071226//cellular response to molecule of fungal origin;GO:0045425//positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process;GO:0007229//integrin-mediated signaling pathway;GO:0043366//beta selection;GO:0002281//macrophage activation involved in immune response;GO:0050853//B cell receptor signaling pathway;GO:0030593//neutrophil chemotaxis;GO:0001945//lymph vessel development;GO:0043306//positive regulation of mast cell degranulation;GO:0051090//regulation of DNA binding transcription factor activity;GO:0046638//positive regulation of alpha-beta T cell differentiation;GO:0042991//transcription factor import into nucleus;GO:0006954//inflammatory response;GO:0045780//positive regulation of bone resorption;GO:0038063//collagen-activated tyrosine kinase receptor signaling pathway;GO:0009887//animal organ morphogenesis;GO:0045588//positive regulation of gamma-delta T cell differentiation;GO:0043313//regulation of neutrophil degranulation;GO:0050715//positive regulation of cytokine secretion;GO:0033630//positive regulation of cell adhesion mediated by integrin","K05855//spleen tyrosine kinase [EC:2.7.10.2]","NP_001128524.1//tyrosine-protein kinase SYK isoform Syk(S) [Homo sapiens];NP_003168.2//tyrosine-protein kinase SYK isoform Syk(L) [Homo sapiens]","6;3//A2MP1;2//1"]
[375307,1414,0.11,0.23,1.06413033741972,0.60837280802969,"*",0.451538,"CATIP","GO:0005634//nucleus;GO:0015629//actin cytoskeleton;GO:0005886//plasma membrane;GO:0005737//cytoplasm","NA","GO:0044782//cilium organization;GO:0030041//actin filament polymerization","K12347//natural resistance-associated macrophage protein 1;K09291//nucleoprotein TPR","NP_001307794.1//ciliogenesis-associated TTC17-interacting protein isoform 1 [Homo sapiens];NP_940961.1//ciliogenesis-associated TTC17-interacting protein isoform 2 [Homo sapiens]","1//3"]
[729978,1412,0.24,0.5,1.05889368905357,0.407494420921065,"*",0.265328,"NPIPB2","GO:0005654//nucleoplasm;GO:0016021//integral component of membrane","NA","NA","K04574//neurofilament heavy polypeptide;K13171//serine/arginine repetitive matrix protein 1","AHY28916.1//nuclear pore complex-interacting protein B type [Homo sapiens]","1//3"]
[8509,4004,6.89,14.35,1.05847484885876,{"v":7.59048175454545e-30,"d":"7.59E-30"},"Up",{"v":2.09078e-31,"d":"2.09E-31"},"NDST2","GO:0016021//integral component of membrane","GO:0016787//hydrolase activity;GO:0015016//[heparan sulfate]-glucosamine N-sulfotransferase activity","NA","K02577//heparan sulfate N-deacetylase/N-sulfotransferase NDST2 [EC:3.1.1.- 2.8.2.-]","XP_015107197.1//PREDICTED: bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 isoform X2 [Vicugna pacos];XP_003409114.1//PREDICTED: bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 isoform X1 [Loxodonta africana]","1//3;3//A2MP1"]
[60484,1795,0.13,0.27,1.05444778402238,0.496027564751792,"*",0.342164,"HAPLN2","GO:0005578//proteinaceous extracellular matrix","GO:0005201//extracellular matrix structural constituent;GO:0005540//hyaluronic acid binding","GO:0007155//cell adhesion;GO:0008065//establishment of blood-nerve barrier;GO:0085029//extracellular matrix assembly;GO:0001501//skeletal system development;GO:0007417//central nervous system development","K06851//hyaluronan and proteoglycan link protein 2","NP_068589.1//hyaluronan and proteoglycan link protein 2 precursor [Homo sapiens]","2//1"]
[3293,1134,0.14,0.29,1.05062607306997,0.608321498861432,"*",0.451538,"HSD17B3","GO:0043231//intracellular membrane-bounded organelle;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0047035//testosterone dehydrogenase (NAD+) activity;GO:0047045//testosterone 17-beta-dehydrogenase (NADP+) activity","GO:0061370//testosterone biosynthetic process;GO:0030539//male genitalia development;GO:0006702//androgen biosynthetic process","K10207//testosterone 17beta-dehydrogenase (NADP+) [EC:1.1.1.64]","NP_000188.1//testosterone 17-beta-dehydrogenase 3 [Homo sapiens]","1//3"]
[100130311,3099,0.15,0.31,1.04730571477836,0.285806842482461,"*",0.1657694,"C17orf107","NA","NA","NA","K04817//nicotinic acetylcholine receptor epsilon","XP_011813756.1//PREDICTED: uncharacterized protein C17orf107 homolog isoform X2 [Colobus angolensis palliatus]","1//3"]
[10878,1484,0.61,1.26,1.04654258593703,0.0879907337878375,"*",0.0403984,"CFHR3","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0072562//blood microparticle","NA","NA","K04004//complement factor H","NP_066303.2//complement factor H-related protein 3 isoform 1 precursor [Homo sapiens];NP_001160096.1//complement factor H-related protein 3 isoform 2 precursor [Homo sapiens]","1//3;5"]
[53833,2171,0.18,0.37,1.03952836418664,0.34457280124031,"*",0.208698,"IL20RB","GO:0016021//integral component of membrane","GO:0042015//interleukin-20 binding","GO:0032733//positive regulation of interleukin-10 production;GO:0048873//homeostasis of number of cells within a tissue;GO:0002765//immune response-inhibiting signal transduction;GO:0001808//negative regulation of type IV hypersensitivity;GO:0032703//negative regulation of interleukin-2 production;GO:0042130//negative regulation of T cell proliferation;GO:0032753//positive regulation of interleukin-4 production;GO:0002437//inflammatory response to antigenic stimulus;GO:0032689//negative regulation of interferon-gamma production","K05137//interleukin 20 receptor beta","XP_010363116.1//PREDICTED: interleukin-20 receptor subunit beta [Rhinopithecus roxellana]","3//A2MP1"]
[10859,2782,0.37,0.76,1.03847414781464,0.0544282325934579,"*",0.0233332,"LILRB1","NA","NA","NA","K06512//leukocyte immunoglobulin-like receptor","XP_016881677.1//PREDICTED: leukocyte immunoglobulin-like receptor subfamily B member 1 isoform X8 [Homo sapiens];XP_016881679.1//PREDICTED: leukocyte immunoglobulin-like receptor subfamily B member 1 isoform X10 [Homo sapiens];XP_016881681.1//PREDICTED: leukocyte immunoglobulin-like receptor subfamily B member 1 isoform X14 [Homo sapiens];XP_016881678.1//PREDICTED: leukocyte immunoglobulin-like receptor subfamily B member 1 isoform X9 [Homo sapiens]","6;3//A2MP1;2//1"]
[8348,467,0.2,0.41,1.03562390973072,0.732286116159388,"*",0.623548,"HIST1H2BO","GO:0005634//nucleus;GO:0000786//nucleosome","GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity","NA","K11252//histone H2B","XP_003502246.1//PREDICTED: histone H2B type 1 isoform X1 [Cricetulus griseus]",4]
[1506,1197,2.8,5.73,1.03310831181194,0.000408118475793555,"Up",0.0001054404,"CTRL","GO:0005615//extracellular space","GO:0004252//serine-type endopeptidase activity","GO:0006508//proteolysis;GO:0007586//digestion","K09632//chymotrypsin-like protease [EC:3.4.21.-]","AAH39716.1//CTRL protein, partial [Homo sapiens]","2//1"]
[348013,1204,0.47,0.96,1.03037364904352,0.12884824,"*",0.0632384,"TMEM255B","GO:0016021//integral component of membrane","NA","NA","NA","NP_872420.1//transmembrane protein 255B isoform 1 [Homo sapiens];NP_001335592.1//transmembrane protein 255B isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[4582,1828,8.64,17.63,1.02892925715671,{"v":4.29868747368421e-16,"d":"4.30E-16"},"Up",{"v":2.76102e-17,"d":"2.76E-17"},"MUC1","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0016324//apical plasma membrane;GO:0005737//cytoplasm;GO:0031982//vesicle;GO:0000790//nuclear chromatin;GO:0005796//Golgi lumen;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0002039//p53 binding;GO:0003712//transcription cofactor activity","GO:0010944//negative regulation of transcription by competitive promoter binding;GO:0007565//female pregnancy;GO:0033629//negative regulation of cell adhesion mediated by integrin;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0001701//in utero embryonic development;GO:0036003//positive regulation of transcription from RNA polymerase II promoter in response to stress;GO:0001666//response to hypoxia;GO:0016266//O-glycan processing;GO:0071300//cellular response to retinoic acid;GO:1902166//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0043618//regulation of transcription from RNA polymerase II promoter in response to stress;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0090240//positive regulation of histone H4 acetylation;GO:0030855//epithelial cell differentiation;GO:0006978//DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator","K06568//mucin-1","NP_001018017.1//mucin-1 isoform 3 precursor [Homo sapiens];NP_001018016.1//mucin-1 isoform 2 precursor [Homo sapiens];NP_001191217.1//mucin-1 isoform 12 precursor [Homo sapiens];NP_001191220.1//mucin-1 isoform 15 precursor [Homo sapiens];NP_001037857.1//mucin-1 isoform 7 precursor [Homo sapiens];NP_001191214.1//mucin-1 isoform 9 precursor [Homo sapiens];NP_001191223.1//mucin-1 isoform 18 precursor [Homo sapiens];NP_001037856.1//mucin-1 isoform 6 precursor [Homo sapiens];NP_001191216.1//mucin-1 isoform 11 precursor [Homo sapiens];NP_001191222.1//mucin-1 isoform 17 precursor [Homo sapiens];NP_002447.4//mucin-1 isoform 1 precursor [Homo sapiens];NP_001191221.1//mucin-1 isoform 16 precursor [Homo sapiens];NP_001191215.1//mucin-1 isoform 10 precursor [Homo sapiens];NP_001037855.1//mucin-1 isoform 5 precursor [Homo sapiens];NP_001191224.1//mucin-1 isoform 19 precursor [Homo sapiens];NP_001191225.1//mucin-1 isoform 20 precursor [Homo sapiens];NP_001037858.1//mucin-1 isoform 8 precursor [Homo sapiens];NP_001191226.1//mucin-1 isoform 21 precursor [Homo sapiens];NP_001191219.1//mucin-1 isoform 14 precursor [Homo sapiens];NP_001191218.1//mucin-1 isoform 13 precursor [Homo sapiens]","1//3;2//1;5"]
[7004,1776,29.76,60.72,1.02879726430743,{"v":1.03116107776744E-51,"d":"1.03E-51"},"Up",{"v":1.387878e-53,"d":"1.39E-53"},"TEAD4","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription factor complex","GO:0043565//sequence-specific DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0001085//RNA polymerase II transcription factor binding","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0035329//hippo signaling;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007517//muscle organ development;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0001501//skeletal system development;GO:0048568//embryonic organ development","K09448//transcriptional enhancer factor","XP_008972017.1//PREDICTED: transcriptional enhancer factor TEF-3 isoform X2 [Pan paniscus];NP_003204.2//transcriptional enhancer factor TEF-3 isoform 1 [Homo sapiens];XP_014697124.1//PREDICTED: transcriptional enhancer factor TEF-3, partial [Equus asinus]","3//A2MP1;2//1"]
[100133093,335,0.27,0.55,1.02647221136119,0.733040605828672,"*",0.623548,"FAM25G","NA","NA","NA","NA","CAI12205.1//family with sequence similarity 25, member B, partial [Homo sapiens]","1//3"]
[1942,1584,7.54,15.35,1.02560222698888,{"v":2.40027317851959e-12,"d":"2.40E-12"},"Up",{"v":2.0706E-13,"d":"2.07E-13"},"EFNA1","GO:0070062//extracellular exosome;GO:0005887//integral component of plasma membrane;GO:0046658//anchored component of plasma membrane;GO:0005886//plasma membrane","GO:0046875//ephrin receptor binding;GO:0005102//receptor binding","GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0016477//cell migration;GO:0050730//regulation of peptidyl-tyrosine phosphorylation;GO:1903051//negative regulation of proteolysis involved in cellular protein catabolic process;GO:0014028//notochord formation;GO:0033628//regulation of cell adhesion mediated by integrin;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0001934//positive regulation of protein phosphorylation;GO:1902004//positive regulation of amyloid-beta formation;GO:0003199//endocardial cushion to mesenchymal transition involved in heart valve formation;GO:0050770//regulation of axonogenesis;GO:0007411//axon guidance;GO:0030182//neuron differentiation;GO:1902961//positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process;GO:0034446//substrate adhesion-dependent cell spreading;GO:0043535//regulation of blood vessel endothelial cell migration;GO:0001525//angiogenesis;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0007267//cell-cell signaling;GO:0048013//ephrin receptor signaling pathway;GO:0043409//negative regulation of MAPK cascade;GO:0045765//regulation of angiogenesis;GO:0003183//mitral valve morphogenesis;GO:0003180//aortic valve morphogenesis;GO:0070244//negative regulation of thymocyte apoptotic process;GO:0043410//positive regulation of MAPK cascade;GO:0050821//protein stabilization;GO:0061002//negative regulation of dendritic spine morphogenesis","K05462//ephrin-A","NP_004419.2//ephrin-A1 isoform a precursor [Homo sapiens];NP_872626.1//ephrin-A1 isoform b precursor [Homo sapiens]","1//3;2//1"]
[283991,1604,36.03,73.28,1.02422085167015,{"v":2.63947054583333e-56,"d":"2.64E-56"},"Up",{"v":3.17252e-58,"d":"3.17E-58"},"UBALD2","NA","NA","NA","K16628//collagen, type VII, alpha","NP_872371.1//UBA-like domain-containing protein 2 [Homo sapiens]","3//A2MP1"]
[170067,5179,0.31,0.63,1.02308361311304,0.0187701886665546,"*",0.006988,"SUPT20HL2","NA","NA","NA","K21245//transcription factor SPT20 homolog","NP_001129705.2//putative transcription factor SPT20 homolog-like 2 precursor [Homo sapiens]","2//1"]
[353376,3203,0.66,1.34,1.02169507109932,0.00507033007163601,"*",0.00163943,"TICAM2","GO:0010008//endosome membrane;GO:0030667//secretory granule membrane;GO:0005783//endoplasmic reticulum;GO:0005770//late endosome;GO:0031902//late endosome membrane;GO:0005768//endosome;GO:0031901//early endosome membrane;GO:0005794//Golgi apparatus;GO:0005769//early endosome;GO:0005886//plasma membrane","GO:0004871//signal transducer activity;GO:0005543//phospholipid binding","GO:0070671//response to interleukin-12;GO:0032755//positive regulation of interleukin-6 production;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0097190//apoptotic signaling pathway;GO:0071650//negative regulation of chemokine (C-C motif) ligand 5 production;GO:0071222//cellular response to lipopolysaccharide;GO:0035669//TRAM-dependent toll-like receptor 4 signaling pathway;GO:0043312//neutrophil degranulation;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0045087//innate immune response;GO:0032729//positive regulation of interferon-gamma production;GO:0034142//toll-like receptor 4 signaling pathway;GO:0007165//signal transduction;GO:0071651//positive regulation of chemokine (C-C motif) ligand 5 production;GO:0051607//defense response to virus;GO:0034144//negative regulation of toll-like receptor 4 signaling pathway;GO:0006954//inflammatory response;GO:0034128//negative regulation of MyD88-independent toll-like receptor signaling pathway;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0070266//necroptotic process;GO:2000494//positive regulation of interleukin-18-mediated signaling pathway;GO:0034145//positive regulation of toll-like receptor 4 signaling pathway","K05409//TRIF-related adaptor molecule","NP_067681.1//TIR domain-containing adapter molecule 2 [Homo sapiens]",7]
[50649,3722,0.35,0.71,1.02046410255972,0.0551359292298716,"*",0.0236642,"ARHGEF4","NA","NA","NA","K05769//Rho guanine nucleotide exchange factor 4/29","XP_005263738.1//PREDICTED: rho guanine nucleotide exchange factor 4 isoform X1 [Homo sapiens]","3//A2MP1;2//1"]
[283518,1639,0.4,0.81,1.01792190799726,0.199852946763602,"*",0.106695,"KCNRG","GO:0005783//endoplasmic reticulum","GO:0042802//identical protein binding","GO:1902260//negative regulation of delayed rectifier potassium channel activity;GO:0051260//protein homooligomerization","K21916//BTB/POZ domain-containing protein KCTD6","NP_775876.1//potassium channel regulatory protein isoform 1 [Homo sapiens];NP_955751.1//potassium channel regulatory protein isoform 2 [Homo sapiens]","1//3;2//1"]
[7755,2065,7.28,14.74,1.01772616889637,{"v":5.42021695729537E-15,"d":"5.42E-15"},"Up",{"v":3.8139e-16,"d":"3.81E-16"},"ZNF205","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_006163049.2//PREDICTED: zinc finger protein 205 isoform X2 [Tupaia chinensis]","1//3;2//1"]
[54897,4875,0.52,1.05,1.01380579952503,0.0097513375872093,"*",0.00335992,"CASZ1","NA","NA","NA","K10955//mucin-2","XP_007978782.1//PREDICTED: zinc finger protein castor homolog 1 isoform X1 [Chlorocebus sabaeus];XP_011539937.1//PREDICTED: zinc finger protein castor homolog 1 isoform X4 [Homo sapiens]","4;2//1"]
[8061,1591,118.05,237.95,1.01126041293185,{"v":5.09546081767442e-164,"d":"5.10E-164"},"Up",{"v":1.371634e-166,"d":"1.37E-166"},"FOSL1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0042734//presynaptic membrane;GO:0043005//neuron projection","GO:0003677//DNA binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0034097//response to cytokine;GO:0032570//response to progesterone;GO:0007296//vitellogenesis;GO:0009629//response to gravity;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0061614//pri-miRNA transcription from RNA polymerase II promoter;GO:0043065//positive regulation of apoptotic process;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0006935//chemotaxis;GO:0031668//cellular response to extracellular stimulus;GO:0008285//negative regulation of cell proliferation;GO:0060674//placenta blood vessel development;GO:0009612//response to mechanical stimulus;GO:0042493//response to drug;GO:0007565//female pregnancy;GO:0051591//response to cAMP;GO:0001701//in utero embryonic development;GO:0007612//learning;GO:2000144//positive regulation of DNA-templated transcription, initiation;GO:0042542//response to hydrogen peroxide;GO:0006968//cellular defense response;GO:0006366//transcription from RNA polymerase II promoter;GO:0009615//response to virus;GO:0045787//positive regulation of cell cycle;GO:0008284//positive regulation of cell proliferation;GO:0051412//response to corticosterone","K04502//fos-like antigen 1","NP_001287786.1//fos-related antigen 1 isoform 5 [Homo sapiens];NP_001287785.1//fos-related antigen 1 isoform 4 [Homo sapiens];NP_005429.1//fos-related antigen 1 isoform 1 [Homo sapiens];XP_021569600.1//fos-related antigen 1 isoform X3 [Carlito syrichta];NP_001287773.1//fos-related antigen 1 isoform 2 [Homo sapiens]","4;1//3"]
[170302,2885,0.66,1.33,1.01088831614274,0.012666432437566,"*",0.00450866,"ARX","NA","NA","NA","K09452//homeobox protein aristaless-related","XP_021520387.1//homeobox protein ARX [Meriones unguiculatus]","2//1"]
[2921,1166,6.09,12.21,1.00354906708107,{"v":2.31216208695652E-7,"d":"2.31E-07"},"Up",{"v":3.4956e-08,"d":"3.50E-08"},"CXCL3","GO:0005615//extracellular space;GO:0005576//extracellular region","GO:0045236//CXCR chemokine receptor binding;GO:0008009//chemokine activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0090023//positive regulation of neutrophil chemotaxis;GO:0030593//neutrophil chemotaxis;GO:0042127//regulation of cell proliferation;GO:0070098//chemokine-mediated signaling pathway;GO:0032496//response to lipopolysaccharide;GO:0031640//killing of cells of other organism;GO:0006954//inflammatory response;GO:0006952//defense response;GO:0006955//immune response","K05505//C-X-C motif chemokine 1/2/3","XP_007997073.1//PREDICTED: C-X-C motif chemokine 3 [Chlorocebus sabaeus]","2//1"]
[578,2203,12.91,25.88,1.00334861668532,{"v":6.31593815091278E-27,"d":"6.32E-27"},"Up",{"v":1.949266e-28,"d":"1.95E-28"},"BAK1","GO:0005783//endoplasmic reticulum;GO:0031307//integral component of mitochondrial outer membrane;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0097145//BAK complex;GO:0046930//pore complex;GO:0005741//mitochondrial outer membrane","GO:0044325//ion channel binding;GO:0042802//identical protein binding;GO:0031072//heat shock protein binding;GO:0046982//protein heterodimerization activity;GO:0051400//BH domain binding;GO:0051087//chaperone binding;GO:0042803//protein homodimerization activity","GO:0031100//animal organ regeneration;GO:0019835//cytolysis;GO:0071260//cellular response to mechanical stimulus;GO:0002352//B cell negative selection;GO:0002262//myeloid cell homeostasis;GO:0007420//brain development;GO:0010332//response to gamma radiation;GO:0045471//response to ethanol;GO:0034644//cellular response to UV;GO:0043065//positive regulation of apoptotic process;GO:1900103//positive regulation of endoplasmic reticulum unfolded protein response;GO:0044346//fibroblast apoptotic process;GO:0008285//negative regulation of cell proliferation;GO:0042493//response to drug;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0001783//B cell apoptotic process;GO:0046902//regulation of mitochondrial membrane permeability;GO:0031018//endocrine pancreas development;GO:0032471//negative regulation of endoplasmic reticulum calcium ion concentration;GO:0001974//blood vessel remodeling;GO:0008053//mitochondrial fusion;GO:0048597//post-embryonic camera-type eye morphogenesis;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0010524//positive regulation of calcium ion transport into cytosol;GO:0051726//regulation of cell cycle;GO:0001782//B cell homeostasis;GO:0010248//establishment or maintenance of transmembrane electrochemical gradient;GO:0014070//response to organic cyclic compound;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0009620//response to fungus;GO:0060068//vagina development;GO:0070242//thymocyte apoptotic process;GO:0097202//activation of cysteine-type endopeptidase activity;GO:0010629//negative regulation of gene expression;GO:0043497//regulation of protein heterodimerization activity;GO:0010225//response to UV-C;GO:0008283//cell proliferation;GO:0043496//regulation of protein homodimerization activity;GO:1902262//apoptotic process involved in blood vessel morphogenesis;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0010046//response to mycotoxin;GO:0001836//release of cytochrome c from mitochondria;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0042542//response to hydrogen peroxide;GO:0035108//limb morphogenesis;GO:0007568//aging;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0008635//activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c;GO:0051881//regulation of mitochondrial membrane potential","K14021//Bcl-2 homologous antagonist/killer","NP_001179.1//bcl-2 homologous antagonist/killer [Homo sapiens]","3//A2MP1"]
[54845,3736,0.02,0.04,1,0.736074176174993,"*",0.623548,"ESRP1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body","GO:0003723//RNA binding;GO:0003729//mRNA binding","GO:0043484//regulation of RNA splicing;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0008543//fibroblast growth factor receptor signaling pathway","K14947//epithelial splicing regulatory protein 1/2","AAH19932.1//ESRP1 protein, partial [Homo sapiens];NP_001030087.2//epithelial splicing regulatory protein 1 isoform 2 [Homo sapiens];NP_001116298.1//epithelial splicing regulatory protein 1 isoform 3 [Homo sapiens];NP_060167.2//epithelial splicing regulatory protein 1 isoform 1 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[9423,5954,0.04,0.08,1,0.496252745233339,"*",0.342164,"NTN1","GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005604//basement membrane","NA","GO:0033564//anterior/posterior axon guidance;GO:0045773//positive regulation of axon extension;GO:0098609//cell-cell adhesion;GO:0030334//regulation of cell migration;GO:0042472//inner ear morphogenesis;GO:2000147//positive regulation of cell motility;GO:0030517//negative regulation of axon extension;GO:0007411//axon guidance;GO:0007097//nuclear migration;GO:0032488//Cdc42 protein signal transduction;GO:0006915//apoptotic process;GO:0001764//neuron migration;GO:0060603//mammary gland duct morphogenesis;GO:0007265//Ras protein signal transduction;GO:0008284//positive regulation of cell proliferation;GO:0006930//substrate-dependent cell migration, cell extension","K06843//netrin 1","NP_004813.2//netrin-1 precursor [Homo sapiens]","2//1"]
[326,2299,0.08,0.16,1,0.609400812098682,"*",0.451538,"AIRE","GO:0005634//nucleus;GO:0016604//nuclear body;GO:0005737//cytoplasm","GO:0042393//histone binding;GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0042802//identical protein binding;GO:0044212//transcription regulatory region DNA binding;GO:0003682//chromatin binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0008270//zinc ion binding;GO:0003712//transcription cofactor activity;GO:0045182//translation regulator activity","GO:0097536//thymus epithelium morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0002509//central tolerance induction to self antigen;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045060//negative thymic T cell selection;GO:0032602//chemokine production;GO:0006959//humoral immune response;GO:2000410//regulation of thymocyte migration;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006955//immune response;GO:0002458//peripheral T cell tolerance induction","K10603//autoimmune regulator","NP_000374.1//autoimmune regulator [Homo sapiens]","3//A2MP1"]
[399693,3596,0.01,0.02,1,0.655392351229138,"*",0.499032,"CCDC187","GO:0005813//centrosome","GO:0008017//microtubule binding","GO:0034453//microtubule anchoring","K06237//collagen, type IV, alpha;K16768//centrosomal protein CEP350","AAH31926.1//MGC50722 protein, partial [Homo sapiens]","1//3"]
[144535,9799,0.03,0.06,1,0.5401564,"*",0.385826,"CFAP54","GO:0005737//cytoplasm;GO:0005930//axoneme","NA","GO:0060294//cilium movement involved in cell motility;GO:0060271//cilium assembly;GO:0030154//cell differentiation;GO:0007283//spermatogenesis","K16547//protein NEDD1","NP_001293013.1//cilia- and flagella-associated protein 54 [Homo sapiens]","1//3"]
[4969,3455,0.01,0.02,1,0.654853952846463,"*",0.499032,"OGN","GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0005783//endoplasmic reticulum;GO:0005615//extracellular space;GO:1903561//extracellular vesicle;GO:0005578//proteinaceous extracellular matrix;GO:0005796//Golgi lumen;GO:0005576//extracellular region;GO:0043202//lysosomal lumen","GO:0008083//growth factor activity","GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0018146//keratan sulfate biosynthetic process;GO:0042340//keratan sulfate catabolic process;GO:0007409//axonogenesis","K08126//osteoglycin (osteoinductive factor, mimecan)","NP_077727.3//mimecan isoform 1 [Homo sapiens];XP_012507285.1//PREDICTED: mimecan isoform X2 [Propithecus coquereli]","4;3//A2MP1"]
[400950,3721,0.23,0.46,1,0.105019496172249,"*",0.0494658,"C2orf91","NA","NA","NA","NA","XP_016859586.1//PREDICTED: uncharacterized protein C2orf91 isoform X1 [Homo sapiens]","1//3"]
[84059,19333,0.01,0.02,1,0.03802253,"*",0.0155194,"ADGRV1","NA","NA","NA","K18263//G-protein coupled receptor 98","XP_016865452.1//PREDICTED: G-protein coupled receptor 98 isoform X1 [Homo sapiens]","3//A2MP1"]
[8764,3519,0.01,0.02,1,0.6544776,"*",0.499032,"TNFRSF14","GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0031625//ubiquitin protein ligase binding;GO:0001618//virus receptor activity;GO:0005031//tumor necrosis factor-activated receptor activity","GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0002741//positive regulation of cytokine secretion involved in immune response;GO:0050829//defense response to Gram-negative bacterium;GO:0097190//apoptotic signaling pathway;GO:0042127//regulation of cell proliferation;GO:0032496//response to lipopolysaccharide;GO:0007166//cell surface receptor signaling pathway;GO:0031295//T cell costimulation;GO:0050830//defense response to Gram-positive bacterium;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:2000406//positive regulation of T cell migration;GO:0006954//inflammatory response;GO:0046642//negative regulation of alpha-beta T cell proliferation;GO:0007275//multicellular organism development;GO:0006955//immune response;GO:0042981//regulation of apoptotic process","K05152//tumor necrosis factor receptor superfamily member 14","XP_004024567.1//PREDICTED: tumor necrosis factor receptor superfamily member 14 isoform X1 [Gorilla gorilla gorilla];NP_003811.2//tumor necrosis factor receptor superfamily member 14 isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[285800,2704,0.03,0.06,1,0.735965402098419,"*",0.623548,"PRR18","NA","NA","NA","K16628//collagen, type VII, alpha;K19720//collagen, type III, alpha","NP_787118.2//proline-rich protein 18 [Homo sapiens]","3//A2MP1"]
[100996492,6943,0.02,0.04,1,0.78247950878697,"*",0.685686,"CTXND1","NA","NA","NA","K15696//RING finger protein 113B;K08857//NIMA (never in mitosis gene a)-related kinase 1/4/5 [EC:2.7.11.1];K04460//serine/threonine-protein phosphatase 5 [EC:3.1.3.16]","EAW99119.1//hCG1648316 [Homo sapiens]","1//3"]
[56649,3549,0.01,0.02,1,0.654209041280263,"*",0.499032,"TMPRSS4","GO:0016021//integral component of membrane","GO:0004252//serine-type endopeptidase activity;GO:0005044//scavenger receptor activity","GO:0006508//proteolysis","K09635//transmembrane protease serine 4 [EC:3.4.21.-]","NP_001167023.1//transmembrane protease serine 4 isoform 5 [Homo sapiens];NP_063947.1//transmembrane protease serine 4 isoform 1 [Homo sapiens];NP_001077416.1//transmembrane protease serine 4 isoform 3 [Homo sapiens];NP_001167022.1//transmembrane protease serine 4 isoform 4 [Homo sapiens]","1//3;3//A2MP1"]
[8856,4335,0.01,0.02,1,0.653940702871206,"*",0.499032,"NR1I2","GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0045111//intermediate filament cytoskeleton","GO:0003707//steroid hormone receptor activity;GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0004879//nuclear receptor activity;GO:0003713//transcription coactivator activity;GO:0008144//drug binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0008270//zinc ion binding;GO:0043565//sequence-specific DNA binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0007165//signal transduction;GO:0006805//xenobiotic metabolic process;GO:0006351//transcription, DNA-templated;GO:0010628//positive regulation of gene expression;GO:0045893//positive regulation of transcription, DNA-templated;GO:0008202//steroid metabolic process;GO:0046618//drug export;GO:0042738//exogenous drug catabolic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0042908//xenobiotic transport","K08540//pregnane X receptor","CAB55493.1//nuclear hormone receptor PRR2-C [Homo sapiens];CAB55490.1//nuclear hormone receptor PRR1-C [Homo sapiens];NP_071285.1//nuclear receptor subfamily 1 group I member 2 isoform 2 [Homo sapiens]","3//A2MP1;2//1"]
[2104,5336,0.01,0.02,1,0.653618987208921,"*",0.499032,"ESRRG","GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0003707//steroid hormone receptor activity;GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0050682//AF-2 domain binding;GO:0003708//retinoic acid receptor activity;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0008270//zinc ion binding;GO:0043565//sequence-specific DNA binding;GO:0005496//steroid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated","K08554//estrogen-related receptor gamma","XP_011896067.1//PREDICTED: estrogen-related receptor gamma isoform X4 [Cercocebus atys];XP_013375331.1//PREDICTED: estrogen-related receptor gamma isoform X2 [Chinchilla lanigera];NP_001230447.1//estrogen-related receptor gamma isoform 6 [Homo sapiens];XP_021022013.1//estrogen-related receptor gamma isoform X2 [Mus caroli];XP_004271081.1//PREDICTED: estrogen-related receptor gamma isoform X2 [Orcinus orca];XP_021125556.1//estrogen-related receptor gamma isoform X1 [Anas platyrhynchos];XP_007072888.1//PREDICTED: estrogen-related receptor gamma [Panthera tigris altaica];XP_019598762.1//PREDICTED: estrogen-related receptor gamma isoform X1 [Rhinolophus sinicus];XP_007165028.1//PREDICTED: estrogen-related receptor gamma-like isoform X2 [Balaenoptera acutorostrata scammoni];OXB65319.1//hypothetical protein ASZ78_002511 [Callipepla squamata]","1//3;3//A2MP1;2//1"]
[100130302,5160,0.06,0.12,1,0.36462342052477,"*",0.225316,"SUPT20HL1","NA","NA","NA","K21245//transcription factor SPT20 homolog","NP_001129706.2//transcription factor SPT20 homolog-like 1 precursor [Homo sapiens]","2//1"]
[80258,3269,0.01,0.02,1,0.653511818986719,"*",0.499032,"EFHC2","NA","GO:0005509//calcium ion binding","GO:1990830//cellular response to leukemia inhibitory factor","NA","NP_079460.2//EF-hand domain-containing family member C2 [Homo sapiens]","3//A2MP1"]
[91947,4074,0.08,0.16,1,0.407572792768535,"*",0.265328,"ARRDC4","GO:0005768//endosome;GO:0005886//plasma membrane;GO:1903561//extracellular vesicle;GO:0005769//early endosome","GO:1990756//protein binding, bridging involved in substrate recognition for ubiquitination","GO:0016567//protein ubiquitination;GO:0008104//protein localization;GO:0015031//protein transport;GO:0051443//positive regulation of ubiquitin-protein transferase activity","K20910//thioredoxin-interacting protein","XP_007988715.1//PREDICTED: arrestin domain-containing protein 4 [Chlorocebus sabaeus]","2//1"]
[284612,3779,0.02,0.04,1,0.735693607504247,"*",0.623548,"SYPL2","GO:0008021//synaptic vesicle;GO:0016021//integral component of membrane;GO:0030285//integral component of synaptic vesicle membrane","GO:0005215//transporter activity","GO:0021762//substantia nigra development;GO:0006874//cellular calcium ion homeostasis","K05456//neuregulin 2","XP_011539585.1//PREDICTED: synaptophysin-like protein 2 isoform X1 [Homo sapiens]","1//3"]
[64218,3230,0.01,0.02,1,0.653404685901639,"*",0.499032,"SEMA4A","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","NA","GO:0045063//T-helper 1 cell differentiation;GO:0001525//angiogenesis;GO:0016525//negative regulation of angiogenesis;GO:0050919//negative chemotaxis;GO:0071526//semaphorin-plexin signaling pathway;GO:0010594//regulation of endothelial cell migration;GO:0008360//regulation of cell shape;GO:0007409//axonogenesis","K06521//semaphorin 4","NP_071762.2//semaphorin-4A isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[222611,5135,0.1,0.2,1,0.211480960694847,"*",0.1143194,"ADGRF2","NA","NA","NA","K08454//G protein-coupled receptor 111","XP_012297067.1//adhesion G-protein coupled receptor F2 [Aotus nancymaae]",6]
[54329,4778,0.01,0.02,1,0.653297587936404,"*",0.499032,"GPR85","GO:0005783//endoplasmic reticulum;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005057//signal transducer activity, downstream of receptor;GO:0004930//G-protein coupled receptor activity","GO:0007165//signal transduction","K04302//G protein-coupled receptor 85","NP_071590.1//probable G-protein coupled receptor 85 [Rattus norvegicus]","6;1//3"]
[5079,8771,0.01,0.02,1,0.395108441754316,"*",0.249274,"PAX5","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0001650//fibrillar center","GO:0003677//DNA binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0006355//regulation of transcription, DNA-templated;GO:0021670//lateral ventricle development;GO:0006351//transcription, DNA-templated;GO:0007283//spermatogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0007568//aging;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0035914//skeletal muscle cell differentiation;GO:0009887//animal organ morphogenesis;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0021987//cerebral cortex development;GO:0006959//humoral immune response;GO:0051573//negative regulation of histone H3-K9 methylation;GO:0007275//multicellular organism development;GO:0030534//adult behavior;GO:0050855//regulation of B cell receptor signaling pathway","K09383//paired box protein 5","XP_011794818.1//PREDICTED: paired box protein Pax-5 isoform X5 [Colobus angolensis palliatus];NP_001267483.1//paired box protein Pax-5 isoform 9 [Homo sapiens];NP_001267482.1//paired box protein Pax-5 isoform 8 [Homo sapiens];NP_001267484.1//paired box protein Pax-5 isoform 10 [Homo sapiens];NP_001267479.1//paired box protein Pax-5 isoform 5 [Homo sapiens];NP_001267478.1//paired box protein Pax-5 isoform 4 [Homo sapiens];NP_001267481.1//paired box protein Pax-5 isoform 7 [Homo sapiens];NP_001267476.1//paired box protein Pax-5 isoform 2 [Homo sapiens];NP_001267477.1//paired box protein Pax-5 isoform 3 [Homo sapiens];NP_057953.1//paired box protein Pax-5 isoform 1 [Homo sapiens];XP_010368268.1//PREDICTED: paired box protein Pax-5 isoform X2 [Rhinopithecus roxellana]","1//3;2//1"]
[7852,1691,0.05,0.1,1,0.73563927267356,"*",0.623548,"CXCR4","GO:0070062//extracellular exosome;GO:0031252//cell leading edge;GO:0005770//late endosome;GO:0031410//cytoplasmic vesicle;GO:0030054//cell junction;GO:0005764//lysosome;GO:0005737//cytoplasm;GO:0009986//cell surface;GO:0043234//protein complex;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005769//early endosome","GO:0019955//cytokine binding;GO:0032027//myosin light chain binding;GO:0031625//ubiquitin protein ligase binding;GO:0019957//C-C chemokine binding;GO:0015026//coreceptor activity;GO:0004930//G-protein coupled receptor activity;GO:0016494//C-X-C chemokine receptor activity;GO:0003779//actin binding;GO:0043130//ubiquitin binding;GO:0004950//chemokine receptor activity;GO:0001618//virus receptor activity","GO:0048714//positive regulation of oligodendrocyte differentiation;GO:0002407//dendritic cell chemotaxis;GO:0050920//regulation of chemotaxis;GO:0006935//chemotaxis;GO:0071345//cellular response to cytokine stimulus;GO:0007186//G-protein coupled receptor signaling pathway;GO:0000187//activation of MAPK activity;GO:0030260//entry into host cell;GO:0019722//calcium-mediated signaling;GO:0006915//apoptotic process;GO:0006954//inflammatory response;GO:0001666//response to hypoxia;GO:0019064//fusion of virus membrane with host plasma membrane;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0043217//myelin maintenance;GO:0009615//response to virus","K04189//C-X-C chemokine receptor type 4","NP_003458.1//C-X-C chemokine receptor type 4 isoform b [Homo sapiens];NP_001334988.1//C-X-C chemokine receptor type 4 isoform d [Homo sapiens];NP_001334985.1//C-X-C chemokine receptor type 4 isoform c [Homo sapiens];NP_001008540.1//C-X-C chemokine receptor type 4 isoform a [Homo sapiens]","1//3;2//1"]
[81706,2211,0.18,0.36,1,0.344644045487439,"*",0.208698,"PPP1R14C","GO:0016020//membrane;GO:0005737//cytoplasm","GO:0004865//protein serine/threonine phosphatase inhibitor activity","GO:0042325//regulation of phosphorylation","K17556//protein phosphatase 1 regulatory subunit 14C","XP_008005744.1//PREDICTED: protein phosphatase 1 regulatory subunit 14C isoform X1 [Chlorocebus sabaeus]","2//1"]
[9173,3909,0.02,0.04,1,0.394912513735991,"*",0.249274,"IL1RL1","GO:0009897//external side of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005578//proteinaceous extracellular matrix","GO:0005057//signal transducer activity, downstream of receptor;GO:0002113//interleukin-33 binding;GO:0004896//cytokine receptor activity;GO:0002114//interleukin-33 receptor activity;GO:0004908//interleukin-1 receptor activity","GO:0002826//negative regulation of T-helper 1 type immune response;GO:0007165//signal transduction;GO:0043032//positive regulation of macrophage activation;GO:0090197//positive regulation of chemokine secretion;GO:0050729//positive regulation of inflammatory response;GO:0032754//positive regulation of interleukin-5 production;GO:0006955//immune response;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0032689//negative regulation of interferon-gamma production","K05171//interleukin 1 receptor-like 1","NP_003847.2//interleukin-1 receptor-like 1 isoform 2 precursor [Homo sapiens];NP_057316.3//interleukin-1 receptor-like 1 isoform 1 precursor [Homo sapiens];XP_009234974.1//PREDICTED: interleukin-1 receptor-like 1 isoform X2 [Pongo abelii]","1//3;4;3//A2MP1"]
[6330,4358,0.01,0.02,1,0.652495470901203,"*",0.499032,"SCN4B","GO:0031226//intrinsic component of plasma membrane;GO:0016021//integral component of membrane;GO:0001518//voltage-gated sodium channel complex;GO:0014704//intercalated disc;GO:0005886//plasma membrane","GO:0086006//voltage-gated sodium channel activity involved in cardiac muscle cell action potential;GO:0044325//ion channel binding;GO:0017080//sodium channel regulator activity;GO:0005248//voltage-gated sodium channel activity","GO:0086016//AV node cell action potential;GO:0035725//sodium ion transmembrane transport;GO:0086012//membrane depolarization during cardiac muscle cell action potential;GO:0086091//regulation of heart rate by cardiac conduction;GO:0010765//positive regulation of sodium ion transport;GO:0086002//cardiac muscle cell action potential involved in contraction;GO:2000649//regulation of sodium ion transmembrane transporter activity;GO:0060048//cardiac muscle contraction;GO:0006814//sodium ion transport;GO:0060307//regulation of ventricular cardiac muscle cell membrane repolarization","K04848//voltage-gated sodium channel type IV beta","XP_009245405.1//PREDICTED: sodium channel subunit beta-4 isoform X2 [Pongo abelii];NP_777594.1//sodium channel subunit beta-4 isoform 1 precursor [Homo sapiens];XP_017378896.1//PREDICTED: sodium channel subunit beta-4 [Cebus capucinus imitator]","1//3;3//A2MP1"]
[57111,1138,0.07,0.14,1,0.735422013585351,"*",0.623548,"RAB25","GO:0070062//extracellular exosome;GO:0031410//cytoplasmic vesicle;GO:0031143//pseudopodium;GO:0031260//pseudopodium membrane","GO:0031489//myosin V binding;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0060627//regulation of vesicle-mediated transport;GO:0010634//positive regulation of epithelial cell migration;GO:0031268//pseudopodium organization;GO:0003382//epithelial cell morphogenesis;GO:0015031//protein transport;GO:0008284//positive regulation of cell proliferation","K07906//Ras-related protein Rab-25","AAF98238.1//unknown [Homo sapiens]","3//A2MP1"]
[9229,5214,0.01,0.02,1,0.652228536082474,"*",0.499032,"DLGAP1","GO:0030054//cell junction;GO:0045202//synapse;GO:0014069//postsynaptic density;GO:0005886//plasma membrane;GO:0045211//postsynaptic membrane","GO:0019904//protein domain specific binding","GO:0007268//chemical synaptic transmission;GO:0006461//protein complex assembly","K15008//discs, large-associated protein 1","NP_001229694.1//disks large-associated protein 1 isoform 7 [Homo sapiens];NP_001003809.1//disks large-associated protein 1 isoform 2 [Homo sapiens];XP_012601395.1//disks large-associated protein 1 isoform X9 [Microcebus murinus];NP_001229695.1//disks large-associated protein 1 isoform 8 [Homo sapiens];XP_007972735.1//PREDICTED: disks large-associated protein 1 isoform X3 [Chlorocebus sabaeus];NP_001229693.1//disks large-associated protein 1 isoform 6 [Homo sapiens];NP_001295319.1//disks large-associated protein 1 isoform 9 [Homo sapiens];NP_001229690.1//disks large-associated protein 1 isoform 3 [Homo sapiens];NP_004737.2//disks large-associated protein 1 isoform 1 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[340024,5183,0.01,0.02,1,0.652175175325207,"*",0.499032,"SLC6A19","GO:0070062//extracellular exosome;GO:0005887//integral component of plasma membrane;GO:0031526//brush border membrane;GO:0005886//plasma membrane","GO:0015175//neutral amino acid transmembrane transporter activity;GO:0005328//neurotransmitter:sodium symporter activity;GO:0015171//amino acid transmembrane transporter activity","GO:0006865//amino acid transport;GO:0007584//response to nutrient","K05334//solute carrier family 6 (neurotransmitter transporter) member 19","NP_001003841.1//sodium-dependent neutral amino acid transporter B(0)AT1 [Homo sapiens]","2//1"]
[26683,939,0.01,0.02,1,1.00047252009278,"*",0.999032,"OR4F3","NA","NA","NA","K04257//olfactory receptor","XP_011933019.1//PREDICTED: olfactory receptor 4F3/4F16/4F29 [Cercocebus atys]","1//3"]
[23127,3943,0.01,0.02,1,0.652121823298429,"*",0.499032,"COLGALT2","NA","NA","NA","K11703//collagen beta-1,O-galactosyltransferase [EC:2.4.1.50]","XP_008983098.1//PREDICTED: procollagen galactosyltransferase 2 isoform X2 [Callithrix jacchus];XP_005319757.1//procollagen galactosyltransferase 2 [Ictidomys tridecemlineatus];XP_004372966.2//PREDICTED: procollagen galactosyltransferase 2 [Trichechus manatus latirostris]","1//3;3//A2MP1"]
[255631,6529,0.01,0.02,1,0.394716779936558,"*",0.249274,"COL24A1","GO:0005788//endoplasmic reticulum lumen;GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005578//proteinaceous extracellular matrix","GO:0005201//extracellular matrix structural constituent","GO:0002244//hematopoietic progenitor cell differentiation","K19721//collagen, type V/XI/XXIV/XXVII, alpha","NP_690850.2//collagen alpha-1(XXIV) chain isoform 1 precursor [Homo sapiens]","6;1//3"]
[50944,9615,0.02,0.04,1,0.629145534604905,"*",0.505908,"SHANK1","GO:0016020//membrane;GO:0030425//dendrite;GO:0060076//excitatory synapse;GO:0005622//intracellular;GO:0030054//cell junction;GO:0014069//postsynaptic density;GO:0043005//neuron projection;GO:0017146//NMDA selective glutamate receptor complex;GO:0005829//cytosol;GO:0043197//dendritic spine;GO:0005886//plasma membrane;GO:0045211//postsynaptic membrane","GO:0042802//identical protein binding;GO:0030160//GKAP/Homer scaffold activity;GO:0097110//scaffold protein binding;GO:0031877//somatostatin receptor binding;GO:0008022//protein C-terminus binding;GO:0035255//ionotropic glutamate receptor binding;GO:0071532//ankyrin repeat binding;GO:0017124//SH3 domain binding;GO:0032403//protein complex binding","GO:0050894//determination of affect;GO:0035418//protein localization to synapse;GO:0007016//cytoskeletal anchoring at plasma membrane;GO:0060074//synapse maturation;GO:0046959//habituation;GO:0007616//long-term memory;GO:0060997//dendritic spine morphogenesis;GO:0035176//social behavior;GO:2000311//regulation of AMPA receptor activity;GO:2000463//positive regulation of excitatory postsynaptic potential;GO:0060999//positive regulation of dendritic spine development;GO:0008306//associative learning;GO:0030534//adult behavior;GO:0042048//olfactory behavior;GO:0060013//righting reflex;GO:0032232//negative regulation of actin filament bundle assembly;GO:0050885//neuromuscular process controlling balance;GO:0071625//vocalization behavior;GO:0006461//protein complex assembly","K15009//SH3 and multiple ankyrin repeat domains protein","NP_057232.2//SH3 and multiple ankyrin repeat domains protein 1 [Homo sapiens]",4]
[1837,2153,0.01,0.02,1,0.651855194046938,"*",0.499032,"DTNA","GO:0030424//axon;GO:0030054//cell junction;GO:0005737//cytoplasm;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0043234//protein complex;GO:0042383//sarcolemma;GO:0016021//integral component of membrane;GO:0045202//synapse","GO:0008270//zinc ion binding;GO:0030165//PDZ domain binding","GO:0006941//striated muscle contraction;GO:0007165//signal transduction;GO:0007268//chemical synaptic transmission;GO:0007274//neuromuscular synaptic transmission","K10366//dystrophin","XP_003784795.1//PREDICTED: dystrobrevin alpha isoform X4 [Otolemur garnettii];XP_008953952.1//PREDICTED: dystrobrevin alpha isoform X6 [Pan paniscus];XP_010333749.1//PREDICTED: dystrobrevin alpha isoform X9 [Saimiri boliviensis boliviensis];XP_007521011.1//PREDICTED: dystrobrevin alpha isoform X9 [Erinaceus europaeus];XP_005258278.1//PREDICTED: dystrobrevin alpha isoform X4 [Homo sapiens];XP_007521009.1//PREDICTED: dystrobrevin alpha isoform X8 [Erinaceus europaeus];XP_018869593.1//PREDICTED: dystrobrevin alpha isoform X10 [Gorilla gorilla gorilla];XP_003784794.1//PREDICTED: dystrobrevin alpha isoform X7 [Otolemur garnettii];XP_010333747.1//PREDICTED: dystrobrevin alpha isoform X7 [Saimiri boliviensis boliviensis];EAX01333.1//dystrobrevin, alpha, isoform CRA_l [Homo sapiens];NP_001185874.1//dystrobrevin alpha isoform 17 [Homo sapiens];XP_010333746.1//PREDICTED: dystrobrevin alpha isoform X6 [Saimiri boliviensis boliviensis];XP_003784796.1//PREDICTED: dystrobrevin alpha isoform X6 [Otolemur garnettii];XP_003784793.1//PREDICTED: dystrobrevin alpha isoform X5 [Otolemur garnettii];NP_001381.2//dystrobrevin alpha isoform 1 [Homo sapiens];BAD92339.1//dystrobrevin alpha isoform 2 variant, partial [Homo sapiens]","6;1//3;4;3//A2MP1;5"]
[30062,3197,0.01,0.02,1,0.651748603384842,"*",0.499032,"RAX","GO:0005634//nucleus","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0007389//pattern specification process;GO:0060173//limb development;GO:0043010//camera-type eye development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007601//visual perception;GO:0021854//hypothalamus development","K09332//retina and anterior neural fold homeobox protein","NP_038463.2//retinal homeobox protein Rx [Homo sapiens]","2//1"]
[150365,4006,0.01,0.02,1,0.651482279176201,"*",0.499032,"MEI1","GO:0005623//cell","NA","GO:0045141//meiotic telomere clustering;GO:0007127//meiosis I;GO:0007141//male meiosis I;GO:0007286//spermatid development","NA","NP_689726.3//meiosis inhibitor protein 1 [Homo sapiens]","3//A2MP1"]
[115861,948,0.01,0.02,1,1.00040980240722,"*",0.999032,"NXNL1","GO:0005739//mitochondrion;GO:0005640//nuclear outer membrane;GO:0005737//cytoplasm","GO:0004791//thioredoxin-disulfide reductase activity","GO:0045494//photoreceptor cell maintenance;GO:0045454//cell redox homeostasis","K17609//nucleoredoxin [EC:1.8.1.8]","XP_017356741.1//PREDICTED: nucleoredoxin-like protein 1 [Cebus capucinus imitator]","1//3"]
[342372,5199,0.01,0.02,1,0.651322589100417,"*",0.499032,"PKD1L3","GO:0070062//extracellular exosome;GO:0009986//cell surface;GO:0005886//plasma membrane;GO:0043235//receptor complex;GO:0034703//cation channel complex","GO:0030246//carbohydrate binding;GO:0005262//calcium channel activity","GO:0001581//detection of chemical stimulus involved in sensory perception of sour taste;GO:0001822//kidney development;GO:0050982//detection of mechanical stimulus;GO:0006812//cation transport;GO:0050915//sensory perception of sour taste;GO:0071468//cellular response to acidic pH","K04989//polycystin 1L3","NP_853514.1//polycystic kidney disease protein 1-like 3 precursor [Homo sapiens]","1//3"]
[8785,2001,0.04,0.08,1,0.735204882787127,"*",0.623548,"MATN4","GO:0005576//extracellular region","GO:0005509//calcium ion binding","GO:0030198//extracellular matrix organization","K19467//matrilin-3","NP_003824.2//matrilin-4 isoform 1 precursor [Homo sapiens];NP_085080.1//matrilin-4 isoform 2 precursor [Homo sapiens];NP_085095.1//matrilin-4 isoform 3 precursor [Homo sapiens]","4;3//A2MP1"]
[92086,994,0.01,0.02,1,1.00034709258447,"*",0.999032,"GGTLC1","NA","GO:0036374//glutathione hydrolase activity","GO:0006751//glutathione catabolic process;GO:1901750//leukotriene D4 biosynthetic process","K18592//gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]","XP_016793052.1//PREDICTED: gamma-glutamyltransferase light chain 1 isoform X4 [Pan troglodytes]","2//1"]
[9635,4246,0.01,0.02,1,0.650950283194513,"*",0.499032,"CLCA2","GO:0005634//nucleus;GO:0005887//integral component of plasma membrane;GO:0005576//extracellular region;GO:0030054//cell junction;GO:0005886//plasma membrane;GO:0009925//basal plasma membrane","GO:0015276//ligand-gated ion channel activity;GO:0046872//metal ion binding;GO:0005229//intracellular calcium activated chloride channel activity;GO:0004222//metalloendopeptidase activity;GO:0005254//chloride channel activity","GO:0006810//transport;GO:0007155//cell adhesion;GO:0034220//ion transmembrane transport","K05028//calcium-activated chloride channel regulator 2","NP_006527.1//calcium-activated chloride channel regulator 2 preproprotein [Homo sapiens]",6]
[1589,2041,0.08,0.16,1,0.609246390066729,"*",0.451538,"CYP21A2","GO:0031090//organelle membrane;GO:0005789//endoplasmic reticulum membrane","GO:0008395//steroid hydroxylase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0020037//heme binding;GO:0004509//steroid 21-monooxygenase activity;GO:0005506//iron ion binding;GO:0004497//monooxygenase activity;GO:0005496//steroid binding","GO:0008202//steroid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006704//glucocorticoid biosynthetic process;GO:0006705//mineralocorticoid biosynthetic process;GO:0016125//sterol metabolic process","K00513//steroid 21-monooxygenase [EC:1.14.14.16]","NP_000491.4//steroid 21-hydroxylase isoform a [Homo sapiens];NP_001122062.3//steroid 21-hydroxylase isoform b [Homo sapiens]","3//A2MP1;7"]
[223075,6843,0.01,0.02,1,0.394247809504951,"*",0.249274,"CCDC129","NA","GO:0005102//receptor binding","NA","NA","NP_001244896.1//coiled-coil domain-containing protein 129 isoform 1 [Homo sapiens];NP_001244897.1//coiled-coil domain-containing protein 129 isoform 3 [Homo sapiens]","4;2//1"]
[1296,4397,0.02,0.04,1,0.735150620119566,"*",0.623548,"COL8A2","GO:0031012//extracellular matrix;GO:0005788//endoplasmic reticulum lumen;GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005578//proteinaceous extracellular matrix;GO:0005604//basement membrane","GO:0005201//extracellular matrix structural constituent;GO:0030674//protein binding, bridging","GO:0050673//epithelial cell proliferation;GO:0098609//cell-cell adhesion;GO:0048593//camera-type eye morphogenesis;GO:0001525//angiogenesis;GO:0030198//extracellular matrix organization;GO:0030574//collagen catabolic process","K19479//collagen, type X, alpha","XP_001158595.3//PREDICTED: collagen alpha-2(VIII) chain [Pan troglodytes];AAH96297.1//COL8A2 protein, partial [Homo sapiens]","1//3;3//A2MP1"]
[23026,6892,0.01,0.02,1,0.735096365461255,"*",0.623548,"MYO16","GO:0016020//membrane;GO:0016459//myosin complex;GO:0005829//cytosol","GO:0003779//actin binding;GO:0005524//ATP binding;GO:0003774//motor activity;GO:0032403//protein complex binding","GO:0048812//neuron projection morphogenesis;GO:0014065//phosphatidylinositol 3-kinase signaling","K17481//myosin XVI","NP_001185879.1//unconventional myosin-XVI isoform 1 [Homo sapiens]","2//1"]
[51233,1336,0.12,0.24,1,0.609194933445946,"*",0.451538,"DRICH1","NA","NA","NA","K20030//palmitoyltransferase ZDHHC5/8 [EC:2.3.1.225];K09341//homeobox protein MSX","NP_057533.2//aspartate-rich protein 1 [Homo sapiens]","3//A2MP1"]
[83481,16018,0.01,0.02,1,0.811123600196257,"*",0.724446,"EPPK1","GO:0005856//cytoskeleton;GO:0016323//basolateral plasma membrane;GO:0042995//cell projection;GO:0016327//apicolateral plasma membrane;GO:0045111//intermediate filament cytoskeleton;GO:0071944//cell periphery;GO:0097356//perinucleolar compartment;GO:0005737//cytoplasm;GO:0030056//hemidesmosome;GO:0005923//bicellular tight junction;GO:0045095//keratin filament","GO:0003723//RNA binding;GO:0008092//cytoskeletal protein binding;GO:0019215//intermediate filament binding","GO:0010839//negative regulation of keratinocyte proliferation;GO:0045109//intermediate filament organization;GO:1905041//regulation of epithelium regeneration;GO:0042060//wound healing;GO:0030336//negative regulation of cell migration;GO:0051548//negative regulation of keratinocyte migration;GO:0050680//negative regulation of epithelial cell proliferation;GO:0061045//negative regulation of wound healing","K10388//plectin","XP_016869378.1//PREDICTED: epiplakin isoform X1 [Homo sapiens]","3//A2MP1"]
[83401,1455,0.11,0.22,1,0.609143485516426,"*",0.451538,"ELOVL3","GO:0005783//endoplasmic reticulum;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0009922//fatty acid elongase activity;GO:0102336//3-oxo-arachidoyl-CoA synthase activity;GO:0102756//very-long-chain 3-ketoacyl-CoA synthase activity;GO:0102337//3-oxo-cerotoyl-CoA synthase activity;GO:0102338//3-oxo-lignoceronyl-CoA synthase activity","GO:0030148//sphingolipid biosynthetic process;GO:0043651//linoleic acid metabolic process;GO:0019367//fatty acid elongation, saturated fatty acid;GO:0036109//alpha-linolenic acid metabolic process;GO:0006636//unsaturated fatty acid biosynthetic process;GO:0034626//fatty acid elongation, polyunsaturated fatty acid;GO:0035338//long-chain fatty-acyl-CoA biosynthetic process;GO:0034625//fatty acid elongation, monounsaturated fatty acid;GO:0042761//very long-chain fatty acid biosynthetic process","K10248//elongation of very long chain fatty acids protein 3 [EC:2.3.1.199]","NP_689523.1//elongation of very long chain fatty acids protein 3 [Homo sapiens]","2//1"]
[220296,3563,0.01,0.02,1,0.650313033773862,"*",0.499032,"HEPACAM","GO:0030424//axon;GO:0005911//cell-cell junction;GO:0016021//integral component of membrane","NA","GO:0034613//cellular protein localization","K06499//carcinoembryonic antigen-related cell adhesion molecule","XP_017379421.1//PREDICTED: hepatocyte cell adhesion molecule isoform X1 [Cebus capucinus imitator]",4]
[1013,2875,0.03,0.06,1,0.73504211881042,"*",0.623548,"CDH15","GO:0070062//extracellular exosome;GO:0005901//caveola;GO:0031594//neuromuscular junction;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005509//calcium ion binding","GO:0051149//positive regulation of muscle cell differentiation;GO:0007155//cell adhesion;GO:0034332//adherens junction organization;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules","K06809//cadherin 15, M-cadherin","NP_004924.1//cadherin-15 preproprotein [Homo sapiens]","2//1"]
[4435,1043,0.5,1,1,0.251460150464396,"*",0.1423692,"CITED1","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0001105//RNA polymerase II transcription coactivator activity;GO:0044212//transcription regulatory region DNA binding;GO:0042803//protein homodimerization activity;GO:0050693//LBD domain binding;GO:0070410//co-SMAD binding;GO:0008022//protein C-terminus binding;GO:0003713//transcription coactivator activity;GO:0003682//chromatin binding;GO:0003700//DNA binding transcription factor activity","GO:0001890//placenta development;GO:0043627//response to estrogen;GO:0007420//brain development;GO:0060711//labyrinthine layer development;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0060712//spongiotrophoblast layer development;GO:0070555//response to interleukin-1;GO:0045668//negative regulation of osteoblast differentiation;GO:0001570//vasculogenesis;GO:0000578//embryonic axis specification;GO:0045892//negative regulation of transcription, DNA-templated;GO:0071105//response to interleukin-11;GO:0071104//response to interleukin-9;GO:0043524//negative regulation of neuron apoptotic process;GO:0010628//positive regulation of gene expression;GO:0006915//apoptotic process;GO:0070670//response to interleukin-4;GO:0030178//negative regulation of Wnt signaling pathway;GO:0034097//response to cytokine;GO:0032496//response to lipopolysaccharide;GO:0070669//response to interleukin-2;GO:0045893//positive regulation of transcription, DNA-templated;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0042438//melanin biosynthetic process;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0034341//response to interferon-gamma;GO:0071559//response to transforming growth factor beta;GO:0030318//melanocyte differentiation;GO:0001656//metanephros development;GO:0071107//response to parathyroid hormone;GO:0032868//response to insulin;GO:0051591//response to cAMP;GO:0070741//response to interleukin-6;GO:0060395//SMAD protein signal transduction;GO:0043473//pigmentation;GO:0006913//nucleocytoplasmic transport;GO:0060231//mesenchymal to epithelial transition;GO:0003340//negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0042981//regulation of apoptotic process","K21361//Cbp/p300-interacting transactivator 2","XP_005657879.1//cbp/p300-interacting transactivator 1 isoform X1 [Sus scrofa];XP_003917925.2//cbp/p300-interacting transactivator 1 isoform X1 [Papio anubis];NP_001138357.1//cbp/p300-interacting transactivator 1 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[388015,4193,0.01,0.02,1,0.649729983535741,"*",0.499032,"RTL1","GO:0016021//integral component of membrane","NA","GO:0007275//multicellular organism development","K04612//calcium-sensing receptor;K21125//mucin-5AC;K17599//transmembrane protein 132","NP_001128360.1//retrotransposon-like protein 1 [Homo sapiens]","2//1"]
[1128,2863,0.03,0.06,1,0.734879426885052,"*",0.623548,"CHRM1","GO:0016020//membrane;GO:0030425//dendrite;GO:0030054//cell junction;GO:0014069//postsynaptic density;GO:0005887//integral component of plasma membrane;GO:0043679//axon terminus;GO:0005886//plasma membrane;GO:0045202//synapse;GO:0045211//postsynaptic membrane","GO:0016907//G-protein coupled acetylcholine receptor activity;GO:0004435//phosphatidylinositol phospholipase C activity;GO:0008144//drug binding","GO:0007399//nervous system development;GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0046541//saliva secretion;GO:0090316//positive regulation of intracellular protein transport;GO:0007274//neuromuscular synaptic transmission;GO:0008283//cell proliferation;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007197//adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway;GO:0007213//G-protein coupled acetylcholine receptor signaling pathway;GO:0043270//positive regulation of ion transport;GO:0007165//signal transduction;GO:0003056//regulation of vascular smooth muscle contraction;GO:0009649//entrainment of circadian clock;GO:0007207//phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway;GO:0050890//cognition;GO:0007271//synaptic transmission, cholinergic;GO:0007603//phototransduction, visible light;GO:0006464//cellular protein modification process;GO:0040012//regulation of locomotion;GO:0008284//positive regulation of cell proliferation","K04129//muscarinic acetylcholine receptor M1","OBS58793.1//hypothetical protein A6R68_10121 [Neotoma lepida]","2//1"]
[50506,6428,0.01,0.02,1,0.3938578512364,"*",0.249274,"DUOX2","GO:0070062//extracellular exosome;GO:0016324//apical plasma membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0005886//plasma membrane","GO:0016174//NAD(P)H oxidase activity;GO:0020037//heme binding;GO:0004601//peroxidase activity;GO:0005509//calcium ion binding","GO:0042446//hormone biosynthetic process;GO:0042335//cuticle development;GO:0055114//oxidation-reduction process;GO:0030878//thyroid gland development;GO:0048839//inner ear development;GO:0048855//adenohypophysis morphogenesis;GO:0030282//bone mineralization;GO:0009566//fertilization;GO:0051591//response to cAMP;GO:0035264//multicellular organism growth;GO:0006979//response to oxidative stress;GO:0006590//thyroid hormone generation;GO:0042744//hydrogen peroxide catabolic process;GO:0019221//cytokine-mediated signaling pathway;GO:0050665//hydrogen peroxide biosynthetic process;GO:0009615//response to virus","K13411//dual oxidase [EC:1.6.3.1 1.11.1.-]","NP_054799.4//dual oxidase 2 precursor [Homo sapiens]",4]
[3841,2172,0.26,0.52,1,0.236891758559767,"*",0.1326232,"KPNA5","GO:0005634//nucleus;GO:0005829//cytosol","GO:0008565//protein transporter activity","GO:0006606//protein import into nucleus","K15042//importin subunit alpha-1","XP_002817323.1//PREDICTED: LOW QUALITY PROTEIN: importin subunit alpha-6 [Pongo abelii]","2//1"]
[5657,1001,0.33,0.66,1,0.407533603076923,"*",0.265328,"PRTN3","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0035578//azurophil granule lumen;GO:0005829//cytosol;GO:0044853//plasma membrane raft;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0004252//serine-type endopeptidase activity;GO:0005102//receptor binding;GO:0019899//enzyme binding;GO:0008236//serine-type peptidase activity","GO:0006509//membrane protein ectodomain proteolysis;GO:0007596//blood coagulation;GO:0043547//positive regulation of GTPase activity;GO:0045217//cell-cell junction maintenance;GO:0019730//antimicrobial humoral response;GO:0072672//neutrophil extravasation;GO:0006508//proteolysis;GO:0097029//mature conventional dendritic cell differentiation;GO:0043312//neutrophil degranulation;GO:0050765//negative regulation of phagocytosis;GO:0008284//positive regulation of cell proliferation;GO:0030574//collagen catabolic process","K01350//myeloblastin [EC:3.4.21.76]","NP_002768.3//myeloblastin precursor [Homo sapiens]","3//A2MP1"]
[64284,2018,0.04,0.08,1,0.734662616315091,"*",0.623548,"RAB17","GO:0070062//extracellular exosome;GO:0030425//dendrite;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0005622//intracellular;GO:0042470//melanosome;GO:0043025//neuronal cell body;GO:0055038//recycling endosome membrane;GO:0030139//endocytic vesicle;GO:0055037//recycling endosome;GO:0005769//early endosome;GO:0005886//plasma membrane","GO:0019003//GDP binding;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0046847//filopodium assembly;GO:0030100//regulation of endocytosis;GO:0051963//regulation of synapse assembly;GO:0060271//cilium assembly;GO:0032401//establishment of melanosome localization;GO:0050773//regulation of dendrite development;GO:0032402//melanosome transport;GO:0002415//immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor;GO:0032456//endocytic recycling;GO:0015031//protein transport;GO:0045056//transcytosis;GO:0051489//regulation of filopodium assembly","K07909//Ras-related protein Rab-17","NP_071894.1//ras-related protein Rab-17 [Homo sapiens]","3//A2MP1"]
[339896,3655,0.01,0.02,1,0.648672566360159,"*",0.499032,"GADL1","NA","GO:0004068//aspartate 1-decarboxylase activity;GO:0004782//sulfinoalanine decarboxylase activity;GO:0030170//pyridoxal phosphate binding","GO:0019752//carboxylic acid metabolic process","K18966//sulfinoalanine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.29 4.1.1.11]","XP_021522121.1//acidic amino acid decarboxylase GADL1 [Aotus nancymaae]","2//1"]
[5244,3826,0.01,0.02,1,0.648514250569476,"*",0.499032,"ABCB4","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005654//nucleoplasm;GO:0005925//focal adhesion;GO:0016324//apical plasma membrane;GO:0030136//clathrin-coated vesicle;GO:0031526//brush border membrane;GO:0046581//intercellular canaliculus;GO:0005737//cytoplasm;GO:0045121//membrane raft;GO:0005887//integral component of plasma membrane;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0005886//plasma membrane","GO:0090554//phosphatidylcholine-translocating ATPase activity;GO:0005524//ATP binding;GO:0042626//ATPase activity, coupled to transmembrane movement of substances;GO:0008559//xenobiotic transmembrane transporting ATPase activity;GO:0008525//phosphatidylcholine transporter activity;GO:0005548//phospholipid transporter activity","GO:0009914//hormone transport;GO:0001890//placenta development;GO:0036146//cellular response to mycotoxin;GO:0035633//maintenance of permeability of blood-brain barrier;GO:0050892//intestinal absorption;GO:0007420//brain development;GO:1903416//response to glycoside;GO:0045332//phospholipid translocation;GO:0097068//response to thyroxine;GO:1904478//regulation of intestinal absorption;GO:0019216//regulation of lipid metabolic process;GO:2001140//positive regulation of phospholipid transport;GO:0033189//response to vitamin A;GO:0042493//response to drug;GO:0032782//bile acid secretion;GO:1901557//response to fenofibrate;GO:0032376//positive regulation of cholesterol transport;GO:0033280//response to vitamin D;GO:1905235//response to quercetin;GO:0001666//response to hypoxia;GO:0071549//cellular response to dexamethasone stimulus;GO:0046686//response to cadmium ion;GO:0046618//drug export;GO:0043215//daunorubicin transport;GO:0055088//lipid homeostasis;GO:0006629//lipid metabolic process;GO:1990963//establishment of blood-retinal barrier;GO:0007595//lactation;GO:0061092//positive regulation of phospholipid translocation;GO:0033231//carbohydrate export;GO:0043278//response to morphine;GO:0071475//cellular hyperosmotic salinity response;GO:2001025//positive regulation of response to drug;GO:1905231//cellular response to borneol;GO:1905233//response to codeine;GO:0006810//transport;GO:0007623//circadian rhythm;GO:0055085//transmembrane transport;GO:0071217//cellular response to external biotic stimulus;GO:0071236//cellular response to antibiotic;GO:1990962//drug transport across blood-brain barrier;GO:1905232//cellular response to L-glutamate;GO:0060856//establishment of blood-brain barrier;GO:1905237//response to cyclosporin A;GO:0097327//response to antineoplastic agent;GO:1903413//cellular response to bile acid;GO:0060548//negative regulation of cell death;GO:0071312//cellular response to alkaloid;GO:0071392//cellular response to estradiol stimulus","K05659//ATP-binding cassette, subfamily B (MDR/TAP), member 4 [EC:3.6.3.44]","NP_061338.1//phosphatidylcholine translocator ABCB4 isoform C [Homo sapiens];EAW76949.1//ATP-binding cassette, sub-family B (MDR/TAP), member 4, isoform CRA_e [Homo sapiens]","3//A2MP1;2//1"]
[9947,4337,0.01,0.02,1,0.648145147410359,"*",0.499032,"MAGEC1","NA","NA","NA","K12464//melanoma-associated antigen D1","NP_005453.2//melanoma-associated antigen C1 [Homo sapiens]",4]
[387357,3983,0.03,0.06,1,0.734608433660299,"*",0.623548,"THEMIS","GO:0005634//nucleus;GO:0008180//COP9 signalosome;GO:0005911//cell-cell junction;GO:0005737//cytoplasm","NA","GO:0050852//T cell receptor signaling pathway;GO:0043383//negative T cell selection;GO:0043368//positive T cell selection;GO:0002250//adaptive immune response","NA","NP_001010923.1//protein THEMIS isoform 2 [Homo sapiens];NP_001158157.1//protein THEMIS isoform 1 [Homo sapiens]","1//3;2//1"]
[494470,4852,0.01,0.02,1,0.648092452682927,"*",0.499032,"RNF165","NA","GO:0008270//zinc ion binding","NA","K17821//RING finger protein 165","XP_011930057.1//PREDICTED: RING finger protein 165 isoform X2 [Cercocebus atys];XP_017713340.1//PREDICTED: RING finger protein 165 isoform X1 [Rhinopithecus bieti]","1//3;2//1"]
[127534,2840,0.03,0.06,1,0.73455425899705,"*",0.623548,"GJB4","GO:0005634//nucleus;GO:0005922//connexin complex;GO:0005730//nucleolus;GO:0016021//integral component of membrane;GO:0030054//cell junction","NA","GO:0007608//sensory perception of smell;GO:0042048//olfactory behavior;GO:0007154//cell communication","K07623//gap junction beta-4 protein","NP_694944.1//gap junction beta-4 protein [Homo sapiens]","2//1"]
[10633,1504,0.11,0.22,1,0.609040615722368,"*",0.451538,"RASL10A","GO:0016020//membrane;GO:0005730//nucleolus;GO:0005886//plasma membrane","GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0007165//signal transduction;GO:0007264//small GTPase mediated signal transduction","K07850//Ras-like protein family member 10A","XP_017820280.1//PREDICTED: ras-like protein family member 10A [Callithrix jacchus]",4]
[495,3582,0.01,0.02,1,0.647934419897586,"*",0.499032,"ATP4A","NA","NA","NA","K01542//H+/K+-exchanging ATPase alpha polypeptide [EC:3.6.3.10]","XP_020832639.1//potassium-transporting ATPase alpha chain 1 [Phascolarctos cinereus]","2//1"]
[5067,4963,0.01,0.02,1,0.647829107517269,"*",0.499032,"CNTN3","NA","NA","NA","K06761//contactin 3","XP_015315007.1//PREDICTED: contactin-3 [Bos taurus]","2//1"]
[3574,1903,0.04,0.08,1,0.734445933638107,"*",0.623548,"IL7","GO:0005615//extracellular space;GO:0005576//extracellular region","GO:0008083//growth factor activity;GO:0005125//cytokine activity;GO:0005139//interleukin-7 receptor binding","GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0010468//regulation of gene expression;GO:0048873//homeostasis of number of cells within a tissue;GO:0030890//positive regulation of B cell proliferation;GO:0046622//positive regulation of organ growth;GO:0006959//humoral immune response;GO:0045582//positive regulation of T cell differentiation;GO:0043086//negative regulation of catalytic activity;GO:0045453//bone resorption;GO:0007267//cell-cell signaling;GO:0043066//negative regulation of apoptotic process;GO:0038111//interleukin-7-mediated signaling pathway;GO:0009887//animal organ morphogenesis;GO:0006955//immune response;GO:0002360//T cell lineage commitment;GO:0008284//positive regulation of cell proliferation","K05431//interleukin 7","NP_001186817.1//interleukin-7 isoform 4 precursor [Homo sapiens];NP_000871.1//interleukin-7 isoform 1 precursor [Homo sapiens];NP_001186815.1//interleukin-7 isoform 2 precursor [Homo sapiens];NP_001186816.1//interleukin-7 isoform 3 precursor [Homo sapiens]","1//3;3//A2MP1"]
[943,3616,0.02,0.04,1,0.734337640224123,"*",0.623548,"TNFRSF8","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0043005//neuron projection","GO:0004888//transmembrane signaling receptor activity;GO:0048406//nerve growth factor binding;GO:0005031//tumor necrosis factor-activated receptor activity","GO:0045556//positive regulation of TRAIL biosynthetic process;GO:0007165//signal transduction;GO:0071260//cellular response to mechanical stimulus;GO:0097190//apoptotic signaling pathway;GO:0032496//response to lipopolysaccharide;GO:0006954//inflammatory response;GO:0042535//positive regulation of tumor necrosis factor biosynthetic process;GO:0043065//positive regulation of apoptotic process;GO:0010977//negative regulation of neuron projection development;GO:0006955//immune response;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0007411//axon guidance;GO:0008285//negative regulation of cell proliferation","K05145//tumor necrosis factor receptor superfamily member 8","XP_011540743.1//PREDICTED: tumor necrosis factor receptor superfamily member 8 isoform X1 [Homo sapiens];NP_001234.3//tumor necrosis factor receptor superfamily member 8 isoform 1 precursor [Homo sapiens]","4;2//1"]
[100129543,2367,0.01,0.02,1,0.999908343859649,"*",0.999032,"ZNF730","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_012364882.1//PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 726 [Nomascus leucogenys]","1//3"]
[79132,2631,0.03,0.06,1,0.734283505492075,"*",0.623548,"DHX58","GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0016787//hydrolase activity;GO:0005524//ATP binding;GO:0008270//zinc ion binding;GO:0004386//helicase activity;GO:0003725//double-stranded RNA binding;GO:0003727//single-stranded RNA binding","GO:0039536//negative regulation of RIG-I signaling pathway;GO:0045824//negative regulation of innate immune response;GO:0032481//positive regulation of type I interferon production;GO:0039534//negative regulation of MDA-5 signaling pathway;GO:0051607//defense response to virus;GO:0045088//regulation of innate immune response;GO:0016032//viral process;GO:1900245//positive regulation of MDA-5 signaling pathway;GO:1900246//positive regulation of RIG-I signaling pathway;GO:0032480//negative regulation of type I interferon production;GO:0009615//response to virus;GO:0045087//innate immune response","K12649//ATP-dependent RNA helicase DHX58 [EC:3.6.3.14]","NP_077024.2//probable ATP-dependent RNA helicase DHX58 [Homo sapiens]","2//1"]
[728378,4337,0.02,0.04,1,0.73422937874097,"*",0.623548,"POTEF","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0072562//blood microparticle;GO:0005938//cell cortex","NA","GO:0021762//substantia nigra development;GO:0001895//retina homeostasis","K17299//POTE ankyrin domain family protein","NP_001093241.1//POTE ankyrin domain family member F [Homo sapiens]","2//1"]
[1001,3704,0.02,0.04,1,0.734121149174528,"*",0.623548,"CDH3","GO:0005913//cell-cell adherens junction;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0005509//calcium ion binding","GO:0048023//positive regulation of melanin biosynthetic process;GO:0051796//negative regulation of timing of catagen;GO:0060901//regulation of hair cycle by canonical Wnt signaling pathway;GO:0007601//visual perception;GO:0031424//keratinization;GO:0032912//negative regulation of transforming growth factor beta2 production;GO:0043568//positive regulation of insulin-like growth factor receptor signaling pathway;GO:1902910//positive regulation of melanosome transport;GO:0022405//hair cycle process;GO:0032773//positive regulation of monophenol monooxygenase activity;GO:0042493//response to drug;GO:0042060//wound healing;GO:0001895//retina homeostasis;GO:0010838//positive regulation of keratinocyte proliferation;GO:0010628//positive regulation of gene expression;GO:0007155//cell adhesion;GO:0060070//canonical Wnt signaling pathway;GO:0034332//adherens junction organization;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules","K06796//cadherin 3, type 1, P-cadherin","NP_001784.2//cadherin-3 isoform 1 preproprotein [Homo sapiens];NP_001304124.1//cadherin-3 isoform 2 precursor [Homo sapiens]","1//3;5"]
[101060211,820,0.1,0.2,1,0.734067046355664,"*",0.623548,"CT45A7","NA","NA","NA","K13180//ATP-dependent RNA helicase DDX26B [EC:3.6.4.-]","NP_001017438.2//cancer/testis antigen family 45 member A6 [Homo sapiens]","1//3"]
[131368,3639,0.01,0.02,1,0.647460783625731,"*",0.499032,"ZPLD1","GO:0016021//integral component of membrane;GO:0005578//proteinaceous extracellular matrix;GO:0030659//cytoplasmic vesicle membrane","NA","NA","K18274//uromodulin","NP_778226.1//zona pellucida-like domain-containing protein 1 isoform 1 precursor [Homo sapiens];XP_007984141.1//PREDICTED: zona pellucida-like domain-containing protein 1 isoform X1 [Chlorocebus sabaeus]","1//3"]
[1908,2630,0.03,0.06,1,0.734012951510685,"*",0.623548,"EDN3","GO:0005615//extracellular space;GO:0005622//intracellular;GO:0005576//extracellular region","GO:0031708//endothelin B receptor binding;GO:0005102//receptor binding;GO:0005179//hormone activity","GO:0010468//regulation of gene expression;GO:0010961//cellular magnesium ion homeostasis;GO:0019229//regulation of vasoconstriction;GO:1901381//positive regulation of potassium ion transmembrane transport;GO:0042310//vasoconstriction;GO:0007166//cell surface receptor signaling pathway;GO:0014826//vein smooth muscle contraction;GO:0048016//inositol phosphate-mediated signaling;GO:0045840//positive regulation of mitotic nuclear division;GO:0045597//positive regulation of cell differentiation;GO:0006874//cellular calcium ion homeostasis;GO:0030318//melanocyte differentiation;GO:0030182//neuron differentiation;GO:0030072//peptide hormone secretion;GO:0010460//positive regulation of heart rate;GO:0007165//signal transduction;GO:0001755//neural crest cell migration;GO:0030593//neutrophil chemotaxis;GO:0003100//regulation of systemic arterial blood pressure by endothelin;GO:0043406//positive regulation of MAP kinase activity;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0007267//cell-cell signaling;GO:0048070//regulation of developmental pigmentation;GO:0008015//blood circulation;GO:0046887//positive regulation of hormone secretion;GO:0007275//multicellular organism development;GO:0008284//positive regulation of cell proliferation","K05227//endothelin-3","XP_018872366.1//PREDICTED: endothelin-3 isoform X1 [Gorilla gorilla gorilla];NP_996917.1//endothelin-3 isoform 1 preproprotein [Homo sapiens];NP_996916.1//endothelin-3 isoform 3 preproprotein [Homo sapiens];NP_996915.1//endothelin-3 isoform 2 preproprotein [Homo sapiens];NP_001289385.1//endothelin-3 isoform 5 preproprotein [Homo sapiens]","1//3;2//1"]
[84734,969,1.36,2.72,1,0.0495004678518519,"*",0.020917,"FAM167B","NA","NA","NA","K03129//transcription initiation factor TFIID subunit 4;K09993//cyclin-dependent kinase inhibitor 1C","XP_012497726.1//PREDICTED: protein FAM167B [Propithecus coquereli]","2//1"]
[2911,6672,0.01,0.02,1,0.393352057295268,"*",0.249274,"GRM1","GO:0030425//dendrite;GO:0005634//nucleus;GO:0014069//postsynaptic density;GO:0005887//integral component of plasma membrane;GO:0042734//presynaptic membrane;GO:0038038//G-protein coupled receptor homodimeric complex;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0099583//neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration;GO:0008066//glutamate receptor activity;GO:0004930//G-protein coupled receptor activity","GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway;GO:0071257//cellular response to electrical stimulus;GO:0000187//activation of MAPK activity;GO:0051966//regulation of synaptic transmission, glutamatergic;GO:0007216//G-protein coupled glutamate receptor signaling pathway;GO:0038042//dimeric G-protein coupled receptor signaling pathway;GO:0007626//locomotory behavior;GO:0051930//regulation of sensory perception of pain;GO:0019233//sensory perception of pain;GO:0007196//adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway;GO:0000186//activation of MAPKK activity","K04603//metabotropic glutamate receptor 1","XP_005961848.1//PREDICTED: metabotropic glutamate receptor 1-like isoform X3 [Pantholops hodgsonii];XP_005659220.1//metabotropic glutamate receptor 1 isoform X2 [Sus scrofa];XP_018885733.1//PREDICTED: metabotropic glutamate receptor 1 isoform X1 [Gorilla gorilla gorilla]","1//3"]
[2,4684,0.01,0.02,1,0.647197951449217,"*",0.499032,"A2M","GO:0070062//extracellular exosome;GO:0072562//blood microparticle","GO:0043120//tumor necrosis factor binding;GO:0002020//protease binding;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005102//receptor binding;GO:0048306//calcium-dependent protein binding;GO:0019959//interleukin-8 binding;GO:0019966//interleukin-1 binding","GO:0048863//stem cell differentiation;GO:0001869//negative regulation of complement activation, lectin pathway","K03910//alpha-2-macroglobulin","XP_017749746.1//PREDICTED: alpha-2-macroglobulin isoform X2 [Rhinopithecus bieti];XP_007965730.1//PREDICTED: alpha-2-macroglobulin isoform X2 [Chlorocebus sabaeus];XP_011920110.1//PREDICTED: alpha-2-macroglobulin isoform X2 [Cercocebus atys]","1//3;5"]
[256158,15670,0.01,0.02,1,0.127623744637123,"*",0.062198,"HMCN2","NA","NA","NA","K17341//hemicentin","NP_001278744.1//hemicentin-2 precursor [Homo sapiens]","1//3"]
[2857,1938,0.04,0.08,1,0.733958864637831,"*",0.623548,"GPR34","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0045028//G-protein coupled purinergic nucleotide receptor activity;GO:0004930//G-protein coupled receptor activity","GO:0007186//G-protein coupled receptor signaling pathway","K08383//G protein-coupled receptor 34","NP_005291.1//probable G-protein coupled receptor 34 [Homo sapiens]","1//3;3//A2MP1"]
[80125,2039,0.1,0.2,1,0.496117612417174,"*",0.342164,"CCDC33","NA","NA","NA","K03006//DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6];K14000//ribosome-binding protein 1","NP_001274110.1//coiled-coil domain-containing protein 33 isoform 3 [Homo sapiens];NP_877592.2//coiled-coil domain-containing protein 33 isoform 2 [Homo sapiens];NP_079331.3//coiled-coil domain-containing protein 33 isoform 1 [Homo sapiens]","1//3;4;3//A2MP1"]
[7010,4343,0.01,0.02,1,0.647040354545454,"*",0.499032,"TEK","GO:0016323//basolateral plasma membrane;GO:0005815//microtubule organizing center;GO:0005925//focal adhesion;GO:0016324//apical plasma membrane;GO:0005902//microvillus;GO:0005737//cytoplasm;GO:0009925//basal plasma membrane;GO:0005884//actin filament;GO:0001725//stress fiber;GO:0009986//cell surface;GO:0045121//membrane raft;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0004713//protein tyrosine kinase activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005524//ATP binding;GO:0004872//receptor activity;GO:0004672//protein kinase activity;GO:0019838//growth factor binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity","GO:2000351//regulation of endothelial cell apoptotic process;GO:0010595//positive regulation of endothelial cell migration;GO:0043627//response to estrogen;GO:0050728//negative regulation of inflammatory response;GO:1902533//positive regulation of intracellular signal transduction;GO:0045766//positive regulation of angiogenesis;GO:0051259//protein oligomerization;GO:0001935//endothelial cell proliferation;GO:0034446//substrate adhesion-dependent cell spreading;GO:0007165//signal transduction;GO:0001525//angiogenesis;GO:0051894//positive regulation of focal adhesion assembly;GO:0007507//heart development;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0043066//negative regulation of apoptotic process;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:0048014//Tie signaling pathway;GO:0001666//response to hypoxia;GO:0046777//protein autophosphorylation;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0002040//sprouting angiogenesis;GO:0051897//positive regulation of protein kinase B signaling;GO:0032878//regulation of establishment or maintenance of cell polarity;GO:0043114//regulation of vascular permeability;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0060216//definitive hemopoiesis;GO:0001934//positive regulation of protein phosphorylation;GO:0001938//positive regulation of endothelial cell proliferation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:2000251//positive regulation of actin cytoskeleton reorganization;GO:0072012//glomerulus vasculature development;GO:0001958//endochondral ossification;GO:0000165//MAPK cascade;GO:0016525//negative regulation of angiogenesis;GO:0050900//leukocyte migration;GO:0043434//response to peptide hormone;GO:0007267//cell-cell signaling;GO:0051591//response to cAMP;GO:0060347//heart trabecula formation;GO:0070374//positive regulation of ERK1 and ERK2 cascade","K05121//endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]","NP_001277006.1//angiopoietin-1 receptor isoform 2 precursor [Homo sapiens];NP_001277007.1//angiopoietin-1 receptor isoform 3 precursor [Homo sapiens];BAD92033.1//TEK tyrosine kinase variant, partial [Homo sapiens]","1//3;4"]
[2313,3995,0.01,0.02,1,0.646830344693281,"*",0.499032,"FLI1","GO:0005634//nucleus;GO:0016604//nuclear body;GO:0005829//cytosol","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0043565//sequence-specific DNA binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0008015//blood circulation;GO:0009887//animal organ morphogenesis;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0035855//megakaryocyte development;GO:0030154//cell differentiation;GO:0006351//transcription, DNA-templated;GO:0007599//hemostasis;GO:0045893//positive regulation of transcription, DNA-templated","K09436//friend leukemia integration 1 transcription factor","XP_012627744.1//Friend leukemia integration 1 transcription factor isoform X2 [Microcebus murinus];NP_001257941.1//Friend leukemia integration 1 transcription factor isoform 4 [Homo sapiens];EFB27417.1//hypothetical protein PANDA_000485, partial [Ailuropoda melanoleuca]","1//3;4;2//1"]
[121601,3819,0.01,0.02,1,0.646777863529412,"*",0.499032,"ANO4","GO:0005622//intracellular;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005229//intracellular calcium activated chloride channel activity;GO:0017128//phospholipid scramblase activity;GO:0046983//protein dimerization activity","GO:0061591//calcium activated galactosylceramide scrambling;GO:0061589//calcium activated phosphatidylserine scrambling;GO:0061590//calcium activated phosphatidylcholine scrambling","K19499//anoctamin-4","XP_011536218.1//PREDICTED: anoctamin-4 isoform X5 [Homo sapiens];XP_009424372.1//PREDICTED: anoctamin-4 isoform X3 [Pan troglodytes];XP_011536213.1//PREDICTED: anoctamin-4 isoform X1 [Homo sapiens]","1//3;3//A2MP1"]
[1910,4490,0.02,0.04,1,0.733904785735337,"*",0.623548,"EDNRB","GO:0031965//nuclear membrane;GO:0045121//membrane raft;GO:0005887//integral component of plasma membrane;GO:0005622//intracellular;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0031702//type 1 angiotensin receptor binding;GO:0017046//peptide hormone binding;GO:0004962//endothelin receptor activity","GO:0008217//regulation of blood pressure;GO:0014043//negative regulation of neuron maturation;GO:0006885//regulation of pH;GO:0071222//cellular response to lipopolysaccharide;GO:0007166//cell surface receptor signaling pathway;GO:0019233//sensory perception of pain;GO:0048246//macrophage chemotaxis;GO:0060406//positive regulation of penile erection;GO:0001755//neural crest cell migration;GO:0019722//calcium-mediated signaling;GO:0086100//endothelin receptor signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0050678//regulation of epithelial cell proliferation;GO:0051930//regulation of sensory perception of pain;GO:0007422//peripheral nervous system development;GO:0007399//nervous system development;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0014070//response to organic cyclic compound;GO:0042310//vasoconstriction;GO:0035645//enteric smooth muscle cell differentiation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0014826//vein smooth muscle contraction;GO:0042045//epithelial fluid transport;GO:0019934//cGMP-mediated signaling;GO:0007194//negative regulation of adenylate cyclase activity;GO:0048265//response to pain;GO:0001934//positive regulation of protein phosphorylation;GO:0031620//regulation of fever generation;GO:0030318//melanocyte differentiation;GO:0042311//vasodilation;GO:0007497//posterior midgut development;GO:0032269//negative regulation of cellular protein metabolic process;GO:0007568//aging;GO:0048484//enteric nervous system development;GO:0035815//positive regulation of renal sodium excretion;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0035810//positive regulation of urine volume;GO:0008284//positive regulation of cell proliferation","K04198//endothelin receptor type B","NP_003982.1//endothelin receptor type B isoform 2 precursor [Homo sapiens];NP_001188326.1//endothelin receptor type B isoform 3 [Homo sapiens];XP_014976756.1//PREDICTED: endothelin B receptor isoform X1 [Macaca mulatta]","4;1//3;3//A2MP1;2//1"]
[25834,7772,0.01,0.02,1,0.733850714801444,"*",0.623548,"MGAT4C","NA","NA","NA","K13748//alpha-1,3-mannosylglycoprotein beta-1,4-N-acetylglucosaminyltransferase C [EC:2.4.1.201 2.4.1.145]","XP_008002375.1//PREDICTED: alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C isoform X3 [Chlorocebus sabaeus];XP_014202736.1//PREDICTED: alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C isoform X1 [Pan paniscus];XP_008002369.1//PREDICTED: alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C isoform X1 [Chlorocebus sabaeus];XP_010353828.1//PREDICTED: alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C isoform X1 [Rhinopithecus roxellana];NP_001338211.1//alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C isoform a precursor [Homo sapiens]","1//3;4"]
[23236,7103,0.01,0.02,1,0.393157866903634,"*",0.249274,"PLCB1","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0031965//nuclear membrane;GO:0016607//nuclear speck;GO:0043209//myelin sheath;GO:0000790//nuclear chromatin;GO:0005737//cytoplasm;GO:0005829//cytosol","GO:0004435//phosphatidylinositol phospholipase C activity;GO:0042803//protein homodimerization activity;GO:0004629//phospholipase C activity;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0005521//lamin binding;GO:0005509//calcium ion binding;GO:0004871//signal transducer activity;GO:0005516//calmodulin binding;GO:0019899//enzyme binding;GO:0005096//GTPase activator activity","GO:0046330//positive regulation of JNK cascade;GO:0040019//positive regulation of embryonic development;GO:0080154//regulation of fertilization;GO:0060466//activation of meiosis involved in egg activation;GO:0070498//interleukin-1-mediated signaling pathway;GO:0007420//brain development;GO:2000560//positive regulation of CD24 biosynthetic process;GO:0021987//cerebral cortex development;GO:0007215//glutamate receptor signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0007213//G-protein coupled acetylcholine receptor signaling pathway;GO:0007165//signal transduction;GO:0046488//phosphatidylinositol metabolic process;GO:0045663//positive regulation of myoblast differentiation;GO:0051726//regulation of cell cycle;GO:0016042//lipid catabolic process;GO:0048639//positive regulation of developmental growth;GO:0048009//insulin-like growth factor receptor signaling pathway;GO:0035556//intracellular signal transduction;GO:0045893//positive regulation of transcription, DNA-templated;GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0032735//positive regulation of interleukin-12 production;GO:0007223//Wnt signaling pathway, calcium modulating pathway;GO:0035722//interleukin-12-mediated signaling pathway;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle;GO:2000344//positive regulation of acrosome reaction;GO:2000438//negative regulation of monocyte extravasation;GO:0007613//memory;GO:0043647//inositol phosphate metabolic process;GO:0035723//interleukin-15-mediated signaling pathway;GO:0045444//fat cell differentiation;GO:0000086//G2/M transition of mitotic cell cycle","K05858//phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]","NP_877398.1//1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform b [Homo sapiens];NP_056007.1//1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform a [Homo sapiens]","3//A2MP1;2//1"]
[23148,4778,0.1,0.2,1,0.28568350367893,"*",0.1657694,"NACAD","GO:0005634//nucleus;GO:0005854//nascent polypeptide-associated complex","NA","GO:0015031//protein transport","K03626//nascent polypeptide-associated complex subunit alpha","NP_001139806.1//NAC-alpha domain-containing protein 1 [Homo sapiens]","1//3"]
[407,1331,0.06,0.12,1,0.733742596832412,"*",0.623548,"ARR3","GO:0001917//photoreceptor inner segment;GO:0045202//synapse;GO:0001750//photoreceptor outer segment;GO:0005737//cytoplasm","GO:0002046//opsin binding;GO:0051219//phosphoprotein binding","GO:0001932//regulation of protein phosphorylation;GO:0007165//signal transduction;GO:0006897//endocytosis;GO:0007601//visual perception","K13801//arrestin-C","XP_017722533.1//PREDICTED: arrestin-C isoform X2 [Rhinopithecus bieti]","2//1"]
[9353,8033,0.01,0.02,1,0.393080244422507,"*",0.249274,"SLIT2","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0009986//cell surface;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0043237//laminin-1 binding;GO:0042802//identical protein binding;GO:0005095//GTPase inhibitor activity;GO:0005509//calcium ion binding;GO:0008201//heparin binding;GO:0048495//Roundabout binding;GO:0042803//protein homodimerization activity;GO:0043394//proteoglycan binding","GO:0031290//retinal ganglion cell axon guidance;GO:0070100//negative regulation of chemokine-mediated signaling pathway;GO:0050929//induction of negative chemotaxis;GO:0071672//negative regulation of smooth muscle cell chemotaxis;GO:0090260//negative regulation of retinal ganglion cell axon guidance;GO:0043065//positive regulation of apoptotic process;GO:0043116//negative regulation of vascular permeability;GO:0007411//axon guidance;GO:0048754//branching morphogenesis of an epithelial tube;GO:0051414//response to cortisol;GO:0008045//motor neuron axon guidance;GO:0050772//positive regulation of axonogenesis;GO:0010593//negative regulation of lamellipodium assembly;GO:0071504//cellular response to heparin;GO:0090288//negative regulation of cellular response to growth factor stimulus;GO:0061364//apoptotic process involved in luteolysis;GO:0001933//negative regulation of protein phosphorylation;GO:0021972//corticospinal neuron axon guidance through spinal cord;GO:0021836//chemorepulsion involved in postnatal olfactory bulb interneuron migration;GO:0050919//negative chemotaxis;GO:0090024//negative regulation of neutrophil chemotaxis;GO:0002042//cell migration involved in sprouting angiogenesis;GO:0090027//negative regulation of monocyte chemotaxis;GO:0030308//negative regulation of cell growth;GO:0048846//axon extension involved in axon guidance;GO:0035385//Roundabout signaling pathway;GO:0010596//negative regulation of endothelial cell migration;GO:0030336//negative regulation of cell migration;GO:0002689//negative regulation of leukocyte chemotaxis;GO:0032870//cellular response to hormone stimulus;GO:0030837//negative regulation of actin filament polymerization;GO:0014912//negative regulation of smooth muscle cell migration;GO:0001657//ureteric bud development;GO:0051058//negative regulation of small GTPase mediated signal transduction;GO:0071676//negative regulation of mononuclear cell migration","K06839//slit 2","NP_001276064.1//slit homolog 2 protein isoform 2 precursor [Homo sapiens];NP_004778.1//slit homolog 2 protein isoform 1 precursor [Homo sapiens];NP_001276065.1//slit homolog 2 protein isoform 3 precursor [Homo sapiens]","3//A2MP1;2//1"]
[10874,834,0.22,0.44,1,0.608886376160729,"*",0.451538,"NMU","GO:0005576//extracellular region;GO:0043195//terminal bouton","GO:0042922//neuromedin U receptor binding;GO:0005102//receptor binding","GO:2000821//regulation of grooming behavior;GO:2000252//negative regulation of feeding behavior;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007165//signal transduction;GO:0050806//positive regulation of synaptic transmission;GO:0042755//eating behavior;GO:0007586//digestion;GO:0006940//regulation of smooth muscle contraction;GO:0045187//regulation of circadian sleep/wake cycle, sleep;GO:0045987//positive regulation of smooth muscle contraction;GO:0046887//positive regulation of hormone secretion;GO:0009648//photoperiodism;GO:0019233//sensory perception of pain;GO:0007218//neuropeptide signaling pathway;GO:0001696//gastric acid secretion","K05249//neuromedin U","NP_001278975.1//neuromedin-U isoform 3 precursor [Homo sapiens];NP_006672.1//neuromedin-U isoform 1 preproprotein [Homo sapiens];NP_001278974.1//neuromedin-U isoform 2 precursor [Homo sapiens]","1//3;3//A2MP1"]
[84229,2731,0.03,0.06,1,0.733688549793754,"*",0.623548,"DRC7","GO:0005856//cytoskeleton;GO:0031514//motile cilium;GO:0005737//cytoplasm","NA","NA","K03006//DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6];K18402//PHD finger protein 20;K09380//zinc finger homeobox protein 4","NP_115645.4//dynein regulatory complex subunit 7 isoform a [Homo sapiens];NP_001276092.1//dynein regulatory complex subunit 7 isoform b [Homo sapiens]","1//3;5"]
[729759,939,0.01,0.02,1,0.999657803056878,"*",0.999032,"OR4F29","NA","NA","NA","K04257//olfactory receptor","XP_011933019.1//PREDICTED: olfactory receptor 4F3/4F16/4F29 [Cercocebus atys]","2//1"]
[90342,6497,0.01,0.02,1,0.392692591321499,"*",0.249274,"FER1L5","NA","NA","NA","K22126//fer-1-like protein 5","XP_014968368.1//PREDICTED: fer-1-like protein 5 isoform X1 [Macaca mulatta]","1//3"]
[84066,897,0.09,0.18,1,0.733634510716653,"*",0.623548,"TEX35","GO:0005634//nucleus;GO:0015630//microtubule cytoskeleton","NA","NA","NA","NP_001164195.1//testis-expressed protein 35 isoform 4 [Homo sapiens];NP_001164193.1//testis-expressed protein 35 isoform 2 [Homo sapiens];NP_115502.2//testis-expressed protein 35 isoform 1 [Homo sapiens];NP_001164194.1//testis-expressed protein 35 isoform 3 [Homo sapiens]","1//3;4"]
[55867,3900,0.07,0.14,1,0.364365031787811,"*",0.225316,"SLC22A11","GO:0070062//extracellular exosome;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016324//apical plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0015143//urate transmembrane transporter activity;GO:0005452//inorganic anion exchanger activity;GO:0008514//organic anion transmembrane transporter activity;GO:0022857//transmembrane transporter activity;GO:0015347//sodium-independent organic anion transmembrane transporter activity","GO:0043252//sodium-independent organic anion transport;GO:0015711//organic anion transport;GO:0015747//urate transport;GO:0046415//urate metabolic process","K08207//MFS transporter, OCT family, solute carrier family 22 (organic anion/cation transporter), member 11","NP_001294914.1//solute carrier family 22 member 11 isoform 2 [Homo sapiens];NP_060954.1//solute carrier family 22 member 11 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[27439,5043,0.05,0.1,1,0.628705025050568,"*",0.505908,"TMEM121B","GO:0016021//integral component of membrane","NA","NA","K03006//DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6];K06236//collagen, type I, alpha","NP_114096.1//cat eye syndrome critical region protein 6 isoform a [Homo sapiens];XP_011544427.1//PREDICTED: cat eye syndrome critical region protein 6 isoform X2 [Homo sapiens]","1//3;3//A2MP1"]
[81399,939,0.01,0.02,1,0.99953257973193,"*",0.999032,"OR4F16","NA","NA","NA","K04257//olfactory receptor","XP_011933019.1//PREDICTED: olfactory receptor 4F3/4F16/4F29 [Cercocebus atys]","1//3"]
[375759,1624,0.05,0.1,1,0.733580479599352,"*",0.623548,"C9orf50","NA","NA","NA","K16628//collagen, type VII, alpha","NP_955382.3//uncharacterized protein C9orf50 [Homo sapiens]","3//A2MP1"]
[8788,4465,0.01,0.02,1,0.644685577678932,"*",0.499032,"DLK1","GO:0005615//extracellular space;GO:0016021//integral component of membrane","GO:0005509//calcium ion binding","GO:0030154//cell differentiation;GO:0045746//negative regulation of Notch signaling pathway","K06051//delta","NP_001304101.1//protein delta homolog 1 isoform 2 preproprotein [Homo sapiens];NP_003827.3//protein delta homolog 1 isoform 1 preproprotein [Homo sapiens]","6;1//3"]
[9843,4284,0.01,0.02,1,0.644529201811125,"*",0.499032,"HEPH","GO:0016323//basolateral plasma membrane;GO:0005622//intracellular;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0048471//perinuclear region of cytoplasm","GO:0004322//ferroxidase activity;GO:0005507//copper ion binding;GO:0016491//oxidoreductase activity;GO:0008198//ferrous iron binding","GO:0006879//cellular iron ion homeostasis;GO:0006826//iron ion transport;GO:0006825//copper ion transport","K14735//hephaestin [EC:1.16.3.1]","NP_001269070.1//hephaestin isoform d precursor [Homo sapiens];NP_620074.3//hephaestin isoform a [Homo sapiens];Q9BQS7.3//RecName: Full=Hephaestin; Flags: Precursor;XP_011529375.1//PREDICTED: hephaestin isoform X1 [Homo sapiens]","1//3;4;3//A2MP1"]
[8110,4077,0.01,0.02,1,0.644372901786436,"*",0.499032,"DPF3","GO:0005654//nucleoplasm;GO:0071565//nBAF complex","GO:0046872//metal ion binding;GO:0008270//zinc ion binding;GO:0003676//nucleic acid binding","GO:0007399//nervous system development;GO:0006355//regulation of transcription, DNA-templated;GO:0016569//covalent chromatin modification;GO:0006351//transcription, DNA-templated","K22198//BRG1-associated factor 45B/C","NP_001267472.1//zinc finger protein DPF3 isoform 3 [Homo sapiens];NP_001267473.1//zinc finger protein DPF3 isoform 4 [Homo sapiens];NP_036206.3//zinc finger protein DPF3 isoform 1 [Homo sapiens];NP_001267471.1//zinc finger protein DPF3 isoform 2 [Homo sapiens]","1//3;4"]
[2672,4512,0.02,0.04,1,0.733364434692976,"*",0.623548,"GFI1","NA","GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0051569//regulation of histone H3-K4 methylation;GO:0030097//hemopoiesis","K09228//KRAB domain-containing zinc finger protein","XP_017890293.1//PREDICTED: zinc finger protein Gfi-1b-like [Ceratina calcarata]","4;2//1"]
[113835,3671,0.01,0.02,1,0.644008496364518,"*",0.499032,"ZNF257","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_009433435.2//PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 257 [Pan troglodytes]","1//3;3//A2MP1"]
[253738,4412,0.01,0.02,1,0.643904456219709,"*",0.499032,"EBF3","GO:0005634//nucleus","GO:0003677//DNA binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0006355//regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007275//multicellular organism development;GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated","K09103//early B-cell factor","BAD90316.1//mKIAA4201 protein, partial [Mus musculus]","2//1"]
[64333,2355,0.03,0.06,1,0.733256459952886,"*",0.623548,"ARHGAP9","GO:0034774//secretory granule lumen;GO:0005829//cytosol;GO:0005576//extracellular region","GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0005096//GTPase activator activity","GO:0007165//signal transduction;GO:0043312//neutrophil degranulation;GO:0051056//regulation of small GTPase mediated signal transduction","K20634//Rho GTPase-activating protein 9","NP_001306779.1//rho GTPase-activating protein 9 isoform 4 [Homo sapiens];EAW97015.1//Rho GTPase activating protein 9, isoform CRA_b [Homo sapiens];NP_115885.2//rho GTPase-activating protein 9 isoform 1 [Homo sapiens];EAW97016.1//Rho GTPase activating protein 9, isoform CRA_c [Homo sapiens];XP_019598008.1//PREDICTED: rho GTPase-activating protein 9 isoform X1 [Rhinolophus sinicus];Q9BRR9.2//RecName: Full=Rho GTPase-activating protein 9; AltName: Full=Rho-type GTPase-activating protein 9","1//3;3//A2MP1;2//1"]
[196883,3415,0.01,0.02,1,0.643696476744186,"*",0.499032,"ADCY4","GO:0016020//membrane;GO:0030425//dendrite;GO:0005622//intracellular;GO:0016021//integral component of membrane;GO:0008074//guanylate cyclase complex, soluble;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0005524//ATP binding;GO:0000166//nucleotide binding;GO:0004016//adenylate cyclase activity;GO:0004383//guanylate cyclase activity","GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0071377//cellular response to glucagon stimulus;GO:0007165//signal transduction;GO:0035556//intracellular signal transduction;GO:0006171//cAMP biosynthetic process;GO:0006182//cGMP biosynthetic process;GO:0007190//activation of adenylate cyclase activity;GO:0034199//activation of protein kinase A activity;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0003091//renal water homeostasis;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway","K08044//adenylate cyclase 4 [EC:4.6.1.1]","CAD62613.1//unnamed protein product, partial [Homo sapiens]","1//3;3//A2MP1"]
[84106,2235,0.07,0.14,1,0.608783593180284,"*",0.451538,"PRAM1","GO:0043234//protein complex","GO:0008289//lipid binding;GO:0019901//protein kinase binding","GO:0007165//signal transduction;GO:0007229//integrin-mediated signaling pathway;GO:0043313//regulation of neutrophil degranulation","K19994//PML-RARA-regulated adapter molecule 1","NP_115528.4//PML-RARA-regulated adapter molecule 1 [Homo sapiens]",4]
[158376,1546,0.05,0.1,1,0.733094557444616,"*",0.623548,"SPAAR","GO:0031902//late endosome membrane;GO:1905103//integral component of lysosomal membrane","NA","GO:0043416//regulation of skeletal muscle tissue regeneration;GO:1904262//negative regulation of TORC1 signaling;GO:0071230//cellular response to amino acid stimulus","NA","EAW58322.1//hCG1652354 [Homo sapiens]","1//3"]
[79632,3821,0.01,0.02,1,0.643332835767896,"*",0.499032,"FAM184A","GO:0005615//extracellular space","NA","NA","K16464//centrosomal protein CEP250;K20283//golgin subfamily A member 4;K16469//rootletin;K20478//golgin subfamily B member 1","NP_078857.5//protein FAM184A isoform 1 [Homo sapiens];XP_009450182.2//PREDICTED: protein FAM184A isoform X4 [Pan troglodytes];XP_009450183.2//PREDICTED: protein FAM184A isoform X5 [Pan troglodytes]","1//3;2//1;5"]
[3784,3262,0.05,0.1,1,0.608680844894515,"*",0.451538,"KCNQ1","GO:0016323//basolateral plasma membrane;GO:0005783//endoplasmic reticulum;GO:0005770//late endosome;GO:0005764//lysosome;GO:0005737//cytoplasm;GO:0034702//ion channel complex;GO:0045121//membrane raft;GO:0005886//plasma membrane;GO:0005769//early endosome;GO:0008076//voltage-gated potassium channel complex;GO:0030659//cytoplasmic vesicle membrane","GO:0015271//outward rectifier potassium channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0086008//voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization;GO:0005251//delayed rectifier potassium channel activity;GO:0034237//protein kinase A regulatory subunit binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0097110//scaffold protein binding;GO:0086089//voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization;GO:0044325//ion channel binding;GO:1902282//voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization;GO:0005516//calmodulin binding;GO:0034236//protein kinase A catalytic subunit binding;GO:0008157//protein phosphatase 1 binding","GO:1902260//negative regulation of delayed rectifier potassium channel activity;GO:0086013//membrane repolarization during cardiac muscle cell action potential;GO:0035690//cellular response to drug;GO:0006349//regulation of gene expression by genetic imprinting;GO:1901381//positive regulation of potassium ion transmembrane transport;GO:0070293//renal absorption;GO:0050892//intestinal absorption;GO:0071320//cellular response to cAMP;GO:0072358//cardiovascular system development;GO:0008016//regulation of heart contraction;GO:0060048//cardiac muscle contraction;GO:0071435//potassium ion export;GO:0048839//inner ear development;GO:0060453//regulation of gastric acid secretion;GO:0060307//regulation of ventricular cardiac muscle cell membrane repolarization;GO:0086005//ventricular cardiac muscle cell action potential;GO:0010460//positive regulation of heart rate;GO:0061337//cardiac conduction;GO:1903817//negative regulation of voltage-gated potassium channel activity;GO:0016458//gene silencing;GO:0071872//cellular response to epinephrine stimulus;GO:0086091//regulation of heart rate by cardiac conduction;GO:0060452//positive regulation of cardiac muscle contraction;GO:0098914//membrane repolarization during atrial cardiac muscle cell action potential;GO:0097623//potassium ion export across plasma membrane;GO:0098915//membrane repolarization during ventricular cardiac muscle cell action potential;GO:0007605//sensory perception of sound;GO:0060306//regulation of membrane repolarization;GO:0060372//regulation of atrial cardiac muscle cell membrane repolarization;GO:0086014//atrial cardiac muscle cell action potential;GO:0071805//potassium ion transmembrane transport;GO:0086011//membrane repolarization during action potential","K04926//potassium voltage-gated channel KQT-like subfamily member 1","NP_861463.1//potassium voltage-gated channel subfamily KQT member 1 isoform 2 precursor [Homo sapiens];NP_000209.2//potassium voltage-gated channel subfamily KQT member 1 isoform 1 [Homo sapiens]","1//3;2//1"]
[56963,3058,0.05,0.1,1,0.608629483756645,"*",0.451538,"RGMA","GO:0070062//extracellular exosome;GO:0009986//cell surface;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0031225//anchored component of membrane;GO:0043005//neuron projection","GO:0005102//receptor binding;GO:1990459//transferrin receptor binding;GO:0015026//coreceptor activity","GO:0030510//regulation of BMP signaling pathway;GO:1900121//negative regulation of receptor binding;GO:0048671//negative regulation of collateral sprouting;GO:0048681//negative regulation of axon regeneration;GO:0051044//positive regulation of membrane protein ectodomain proteolysis;GO:0010976//positive regulation of neuron projection development;GO:0043547//positive regulation of GTPase activity;GO:0030509//BMP signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0031175//neuron projection development;GO:0001843//neural tube closure","K06847//RGM domain family","NP_064596.2//repulsive guidance molecule A isoform 3 [Homo sapiens];AAH15886.2//RGMA protein, partial [Homo sapiens];NP_001159755.1//repulsive guidance molecule A isoform 1 [Homo sapiens]","1//3;2//1"]
[2984,3850,0.01,0.02,1,0.642865900645161,"*",0.499032,"GUCY2C","GO:0016021//integral component of membrane;GO:0008074//guanylate cyclase complex, soluble;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane","GO:0005524//ATP binding;GO:0015643//toxic substance binding;GO:0004672//protein kinase activity;GO:0005525//GTP binding;GO:0004383//guanylate cyclase activity","GO:0006182//cGMP biosynthetic process;GO:0007165//signal transduction;GO:0007586//digestion;GO:0042127//regulation of cell proliferation;GO:0035556//intracellular signal transduction;GO:0007168//receptor guanylyl cyclase signaling pathway;GO:0009636//response to toxic substance","K12320//heat-stable enterotoxin receptor [EC:4.6.1.2]","NP_004954.2//heat-stable enterotoxin receptor precursor [Homo sapiens]","3//A2MP1"]
[6753,3764,0.01,0.02,1,0.642347878162772,"*",0.499032,"SSTR3","GO:0060170//ciliary membrane;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0097730//non-motile cilium;GO:0043005//neuron projection","GO:0005102//receptor binding;GO:0042923//neuropeptide binding;GO:0004994//somatostatin receptor activity;GO:0004930//G-protein coupled receptor activity","GO:0021549//cerebellum development;GO:0071385//cellular response to glucocorticoid stimulus;GO:0007267//cell-cell signaling;GO:0007283//spermatogenesis;GO:0042594//response to starvation;GO:0030900//forebrain development;GO:0007268//chemical synaptic transmission;GO:0008628//hormone-mediated apoptotic signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0008285//negative regulation of cell proliferation;GO:0071392//cellular response to estradiol stimulus;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger","K04219//somatostatin receptor 3","XP_003821603.1//PREDICTED: somatostatin receptor type 3 [Pan paniscus];NP_001042.1//somatostatin receptor type 3 [Homo sapiens]","4;2//1"]
[55799,3689,0.01,0.02,1,0.64219263417385,"*",0.499032,"CACNA2D3","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005244//voltage-gated ion channel activity;GO:0046872//metal ion binding;GO:0005262//calcium channel activity","GO:0061337//cardiac conduction","K04860//voltage-dependent calcium channel alpha-2/delta-3","NP_060868.2//voltage-dependent calcium channel subunit alpha-2/delta-3 precursor [Homo sapiens]","2//1"]
[353189,5334,0.03,0.06,1,0.608578131285859,"*",0.451538,"SLCO4C1","GO:0070062//extracellular exosome;GO:0016323//basolateral plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane;GO:0005886//plasma membrane;GO:0035577//azurophil granule membrane","GO:0005215//transporter activity;GO:0015347//sodium-independent organic anion transmembrane transporter activity","GO:0043252//sodium-independent organic anion transport;GO:0030154//cell differentiation;GO:0007275//multicellular organism development;GO:0043312//neutrophil degranulation;GO:0006811//ion transport;GO:0007283//spermatogenesis","K14355//solute carrier organic anion transporter family, member 4C","NP_851322.3//solute carrier organic anion transporter family member 4C1 [Homo sapiens]",4]
[24138,4034,3.89,7.78,1,{"v":3.03389188299817e-15,"d":"3.03E-15"},"Up",{"v":2.0778E-16,"d":"2.08E-16"},"IFIT5","GO:0043231//intracellular membrane-bounded organelle;GO:0015629//actin cytoskeleton;GO:0032587//ruffle membrane;GO:0045177//apical part of cell;GO:0005886//plasma membrane;GO:0008385//IkappaB kinase complex;GO:0042597//periplasmic space","GO:0003723//RNA binding;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0000339//RNA cap binding;GO:0008266//poly(U) RNA binding;GO:0000049//tRNA binding;GO:0003690//double-stranded DNA binding;GO:0003727//single-stranded RNA binding","GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045071//negative regulation of viral genome replication;GO:0051607//defense response to virus;GO:0045087//innate immune response","K14217//interferon-induced protein with tetratricopeptide repeats 1","NP_036552.1//interferon-induced protein with tetratricopeptide repeats 5 [Homo sapiens]","2//1"]
[392509,1132,0.07,0.14,1,0.732878798616732,"*",0.623548,"ARL13A","GO:0005622//intracellular","GO:0005525//GTP binding","GO:0007264//small GTPase mediated signal transduction","K07961//ADP-ribosylation factor-like protein 13","NP_001155963.1//ADP-ribosylation factor-like protein 13A [Homo sapiens]","1//3"]
[4744,3721,0.01,0.02,1,0.641727352117211,"*",0.499032,"NEFH","GO:0030424//axon;GO:0097418//neurofibrillary tangle;GO:0005883//neurofilament;GO:0043209//myelin sheath;GO:0005739//mitochondrion;GO:0014069//postsynaptic density;GO:0005737//cytoplasm","GO:0070840//dynein complex binding;GO:0030674//protein binding, bridging;GO:0005198//structural molecule activity;GO:0005200//structural constituent of cytoskeleton;GO:0019894//kinesin binding;GO:0008017//microtubule binding;GO:0019901//protein kinase binding","GO:0000226//microtubule cytoskeleton organization;GO:0061564//axon development;GO:0033693//neurofilament bundle assembly;GO:0007409//axonogenesis;GO:1990830//cellular response to leukemia inhibitory factor;GO:0048936//peripheral nervous system neuron axonogenesis;GO:0030031//cell projection assembly;GO:1902513//regulation of organelle transport along microtubule","K04574//neurofilament heavy polypeptide","NP_066554.2//neurofilament heavy polypeptide [Homo sapiens]","3//A2MP1"]
[169044,6365,0.01,0.02,1,0.39203533287388,"*",0.249274,"COL22A1","GO:0005788//endoplasmic reticulum lumen;GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005578//proteinaceous extracellular matrix","NA","NA","K16630//collagen, type XXII, alpha","NP_690848.1//collagen alpha-1(XXII) chain precursor [Homo sapiens]","2//1"]
[23533,4368,0.01,0.02,1,0.641211162162162,"*",0.499032,"PIK3R5","GO:0005944//phosphatidylinositol 3-kinase complex, class IB;GO:0016020//membrane;GO:0005634//nucleus;GO:0005815//microtubule organizing center;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005942//phosphatidylinositol 3-kinase complex;GO:0005886//plasma membrane","GO:0031683//G-protein beta/gamma-subunit complex binding;GO:0046935//1-phosphatidylinositol-3-kinase regulator activity;GO:0016301//kinase activity;GO:0046934//phosphatidylinositol-4,5-bisphosphate 3-kinase activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0051897//positive regulation of protein kinase B signaling;GO:0043406//positive regulation of MAP kinase activity;GO:0030168//platelet activation;GO:0006661//phosphatidylinositol biosynthetic process;GO:0014065//phosphatidylinositol 3-kinase signaling","K21290//phosphoinositide-3-kinase regulatory subunit 5/6","NP_055123.2//phosphoinositide 3-kinase regulatory subunit 5 isoform 1 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[54102,4102,0.01,0.02,1,0.640953378467476,"*",0.499032,"CLIC6","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0034707//chloride channel complex;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0005244//voltage-gated ion channel activity;GO:0005254//chloride channel activity","GO:1902476//chloride transmembrane transport","K05026//chloride intracellular channel protein 6","NP_444507.1//chloride intracellular channel protein 6 isoform 2 [Homo sapiens];NP_001303938.1//chloride intracellular channel protein 6 isoform 1 [Homo sapiens]","1//3;2//1"]
[2239,3714,0.01,0.02,1,0.64085032301632,"*",0.499032,"GPC4","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0009897//external side of plasma membrane;GO:0031225//anchored component of membrane;GO:0005578//proteinaceous extracellular matrix;GO:0005796//Golgi lumen;GO:0005887//integral component of plasma membrane;GO:0043202//lysosomal lumen;GO:0005886//plasma membrane","GO:0043395//heparan sulfate proteoglycan binding;GO:1904929//coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway","GO:0001523//retinoid metabolic process;GO:0009653//anatomical structure morphogenesis;GO:0008283//cell proliferation;GO:0006027//glycosaminoglycan catabolic process;GO:0006024//glycosaminoglycan biosynthetic process;GO:0030203//glycosaminoglycan metabolic process","K08110//glypican 4","NP_001439.2//glypican-4 precursor [Homo sapiens]","2//1"]
[3587,3672,0.01,0.02,1,0.640798807717042,"*",0.499032,"IL10RA","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004920//interleukin-10 receptor activity;GO:0004872//receptor activity;GO:0019969//interleukin-10 binding;GO:0004871//signal transducer activity","GO:0032496//response to lipopolysaccharide;GO:0050807//regulation of synapse organization","K05134//interleukin 10 receptor alpha","NP_001549.2//interleukin-10 receptor subunit alpha precursor [Homo sapiens]","3//A2MP1"]
[100507003,1557,0.05,0.1,1,0.732663166752483,"*",0.623548,"GFY","GO:0030173//integral component of Golgi membrane;GO:0016021//integral component of membrane","NA","GO:0007608//sensory perception of smell;GO:0097499//protein localization to non-motile cilium;GO:0050896//response to stimulus;GO:1905515//non-motile cilium assembly","K10955//mucin-2;K03006//DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6];K12567//titin [EC:2.7.11.1];K04574//neurofilament heavy polypeptide;K04006//decay accelerating factor","NP_001182185.1//Golgi-associated olfactory signaling regulator precursor [Homo sapiens]","1//3"]
[1003,4149,0.01,0.02,1,0.640541355403777,"*",0.499032,"CDH5","GO:0016020//membrane;GO:0009986//cell surface;GO:0009897//external side of plasma membrane;GO:0005913//cell-cell adherens junction;GO:0005911//cell-cell junction;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0005923//bicellular tight junction;GO:0005886//plasma membrane","GO:0044325//ion channel binding;GO:0005509//calcium ion binding;GO:0019903//protein phosphatase binding;GO:0005102//receptor binding;GO:0008013//beta-catenin binding","GO:0007179//transforming growth factor beta receptor signaling pathway;GO:2000114//regulation of establishment of cell polarity;GO:0007043//cell-cell junction assembly;GO:0034332//adherens junction organization;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:1903142//positive regulation of establishment of endothelial barrier;GO:0008285//negative regulation of cell proliferation;GO:0001955//blood vessel maturation","K06533//cadherin 5, type 2, VE-cadherin","BAD93145.1//cadherin 5, type 2 preproprotein variant, partial [Homo sapiens]",4]
[441308,939,0.01,0.02,1,0.999157097921362,"*",0.999032,"OR4F21","NA","NA","NA","K04257//olfactory receptor","XP_011933019.1//PREDICTED: olfactory receptor 4F3/4F16/4F29 [Cercocebus atys]","1//3"]
[3059,2050,0.04,0.08,1,0.732609278611356,"*",0.623548,"HCLS1","GO:0005634//nucleus;GO:0005667//transcription factor complex;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0003779//actin binding;GO:0017124//SH3 domain binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0019901//protein kinase binding;GO:0032403//protein complex binding","GO:0030833//regulation of actin filament polymerization;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0051897//positive regulation of protein kinase B signaling;GO:0006355//regulation of transcription, DNA-templated;GO:0035556//intracellular signal transduction;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0045651//positive regulation of macrophage differentiation;GO:0071345//cellular response to cytokine stimulus;GO:0030041//actin filament polymerization;GO:2000251//positive regulation of actin cytoskeleton reorganization;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0030854//positive regulation of granulocyte differentiation;GO:0030218//erythrocyte differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0009725//response to hormone;GO:2000107//negative regulation of leukocyte apoptotic process;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0008284//positive regulation of cell proliferation;GO:0042993//positive regulation of transcription factor import into nucleus","K06106//cortactin","NP_005326.2//hematopoietic lineage cell-specific protein isoform 1 [Homo sapiens];NP_001278970.1//hematopoietic lineage cell-specific protein isoform 2 [Homo sapiens]","1//3;5"]
[6096,3604,0.01,0.02,1,0.64048988976378,"*",0.499032,"RORB","GO:0005634//nucleus","GO:0003707//steroid hormone receptor activity;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0008270//zinc ion binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0008134//transcription factor binding;GO:0004879//nuclear receptor activity","GO:0046548//retinal rod cell development;GO:0042752//regulation of circadian rhythm;GO:0045668//negative regulation of osteoblast differentiation;GO:0006351//transcription, DNA-templated;GO:0046549//retinal cone cell development","K08533//RAR-related orphan receptor beta","AAA42095.1//transcription factor, partial [Rattus norvegicus]","3//A2MP1"]
[4917,1986,0.08,0.16,1,0.608475452336764,"*",0.451538,"NTN3","GO:0005794//Golgi apparatus;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix","GO:0005102//receptor binding","GO:0007411//axon guidance","K06844//netrin 3","NP_006172.1//netrin-3 precursor [Homo sapiens]","2//1"]
[1573,1927,0.04,0.08,1,0.73250152610678,"*",0.623548,"CYP2J2","GO:0070062//extracellular exosome","GO:0020037//heme binding;GO:0071614//linoleic acid epoxygenase activity;GO:0005506//iron ion binding;GO:0008405//arachidonic acid 11,12-epoxygenase activity;GO:0008404//arachidonic acid 14,15-epoxygenase activity;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen","GO:0043651//linoleic acid metabolic process;GO:0019373//epoxygenase P450 pathway","K07418//cytochrome P450 family 2 subfamily J [EC:1.14.14.1]","BAG37780.1//unnamed protein product [Homo sapiens]","3//A2MP1"]
[730755,880,0.19,0.38,1,0.60842412585407,"*",0.451538,"KRTAP2-3","GO:0005829//cytosol;GO:0045095//keratin filament","NA","GO:0031424//keratinization","K02893//large subunit ribosomal protein L23Ae;K00933//creatine kinase [EC:2.7.3.2]","NP_149440.1//keratin-associated protein 2-4 [Homo sapiens]","1//3"]
[137872,1907,0.17,0.34,1,0.407455246298789,"*",0.265328,"ADHFE1","GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0005739//mitochondrion","GO:0004022//alcohol dehydrogenase (NAD) activity;GO:0046872//metal ion binding;GO:0047988//hydroxyacid-oxoacid transhydrogenase activity","GO:0015993//molecular hydrogen transport;GO:0006103//2-oxoglutarate metabolic process","K11173//hydroxyacid-oxoacid transhydrogenase [EC:1.1.99.24]","NP_653251.2//hydroxyacid-oxoacid transhydrogenase, mitochondrial [Homo sapiens]","2//1"]
[145226,1934,0.04,0.08,1,0.732447661739834,"*",0.623548,"RDH12","GO:0060342//photoreceptor inner segment membrane;GO:0005622//intracellular","GO:0052650//NADP-retinol dehydrogenase activity;GO:0004745//retinol dehydrogenase activity;GO:0016491//oxidoreductase activity","GO:0001523//retinoid metabolic process;GO:0042572//retinol metabolic process;GO:0050896//response to stimulus;GO:0007601//visual perception;GO:0045494//photoreceptor cell maintenance","K11153//retinol dehydrogenase 12 [EC:1.1.1.300]","NP_689656.2//retinol dehydrogenase 12 precursor [Homo sapiens]","2//1"]
[139378,9931,0.01,0.02,1,0.732393805294118,"*",0.623548,"ADGRG4","GO:0016021//integral component of membrane","GO:0004930//G-protein coupled receptor activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0007166//cell surface receptor signaling pathway","K08455//G protein-coupled receptor 112","NP_722576.3//adhesion G-protein coupled receptor G4 [Homo sapiens]","3//A2MP1"]
[338872,1849,0.06,0.12,1,0.732232283466882,"*",0.623548,"C1QTNF9","NA","NA","NA","K06237//collagen, type IV, alpha","XP_017949521.1//PREDICTED: otolin-1 [Xenopus tropicalis]","4;1//3"]
[100128569,671,5.67,11.33,0.998727220878287,0.000368868721367521,"*",{"v":9.4561e-05,"d":"9.46E-05"},"C19orf71","NA","NA","NA","K10955//mucin-2","NP_001129052.1//uncharacterized protein C19orf71 [Homo sapiens]","1//3"]
[604,3286,3.15,6.29,0.99770818849201,{"v":2.83858834224599E-10,"d":"2.84E-10"},"*",{"v":2.9907e-11,"d":"2.99E-11"},"BCL6","GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0005657//replication fork","GO:0042802//identical protein binding;GO:0003682//chromatin binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0045591//positive regulation of regulatory T cell differentiation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0030308//negative regulation of cell growth;GO:0043065//positive regulation of apoptotic process;GO:0000060//protein import into nucleus, translocation;GO:0006974//cellular response to DNA damage stimulus","K15618//B-cell lymphoma 6 protein","XP_003256686.1//PREDICTED: B-cell lymphoma 6 protein [Nomascus leucogenys];XP_006156796.1//PREDICTED: B-cell lymphoma 6 protein isoform X2 [Tupaia chinensis]","4;1//3"]
[55150,765,2.3,4.59,0.996860292469433,0.0210742473161034,"*",0.0079632,"C19orf73","NA","NA","NA","NA","XP_010349484.1//PREDICTED: putative uncharacterized protein C19orf73 homolog [Saimiri boliviensis boliviensis]","2//1"]
[2323,1090,1.6,3.18,0.990954860396993,0.0210777393206297,"*",0.0079632,"FLT3LG","GO:0016020//membrane;GO:0005615//extracellular space;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0031233//intrinsic component of external side of plasma membrane","GO:0005125//cytokine activity;GO:0016301//kinase activity;GO:0030971//receptor tyrosine kinase binding;GO:0005102//receptor binding;GO:0042803//protein homodimerization activity","GO:0030098//lymphocyte differentiation;GO:0090290//positive regulation of osteoclast proliferation;GO:0007165//signal transduction;GO:0071866//negative regulation of apoptotic process in bone marrow;GO:0030885//regulation of myeloid dendritic cell activation;GO:0048873//homeostasis of number of cells within a tissue;GO:0035162//embryonic hemopoiesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0032825//positive regulation of natural killer cell differentiation;GO:0045663//positive regulation of myoblast differentiation;GO:0001934//positive regulation of protein phosphorylation;GO:1901741//positive regulation of myoblast fusion;GO:0045787//positive regulation of cell cycle;GO:0008284//positive regulation of cell proliferation;GO:0071864//positive regulation of cell proliferation in bone marrow","K05454//fms-related tyrosine kinase 3 ligand","XP_007995738.1//PREDICTED: fms-related tyrosine kinase 3 ligand isoform X1 [Chlorocebus sabaeus];NP_001450.2//fms-related tyrosine kinase 3 ligand isoform 1 precursor [Homo sapiens];EAW52488.1//fms-related tyrosine kinase 3 ligand, isoform CRA_a [Homo sapiens]","1//3;3//A2MP1"]
[6774,4955,35.33,70.19,0.990371754548179,{"v":1.19197308255319e-159,"d":"1.19E-159"},"*",{"v":3.50712E-162,"d":"3.51E-162"},"STAT3","NA","NA","NA","K04692//signal transducer and activator of transcription 3","XP_018883234.1//PREDICTED: signal transducer and activator of transcription 3 isoform X4 [Gorilla gorilla gorilla];XP_005369087.1//PREDICTED: signal transducer and activator of transcription 3 isoform X1 [Microtus ochrogaster];XP_006092427.1//PREDICTED: signal transducer and activator of transcription 3 isoform X1 [Myotis lucifugus]","1//3;3//A2MP1;2//1"]
[126374,2204,11.59,23,0.988753294825266,{"v":1.90208139643436E-23,"d":"1.90E-23"},"*",{"v":7.34684e-25,"d":"7.35E-25"},"WTIP","GO:0005634//nucleus;GO:0005667//transcription factor complex;GO:0005911//cell-cell junction;GO:0000932//P-body;GO:0005912//adherens junction","GO:0046872//metal ion binding;GO:0003714//transcription corepressor activity","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0035331//negative regulation of hippo signaling;GO:0030030//cell projection organization;GO:0001666//response to hypoxia;GO:0007010//cytoskeleton organization;GO:0035195//gene silencing by miRNA;GO:2000637//positive regulation of gene silencing by miRNA;GO:0022604//regulation of cell morphogenesis","K16682//LIM domain-containing protein","NP_001073905.1//Wilms tumor protein 1-interacting protein [Homo sapiens]","1//3"]
[440836,970,4.93,9.78,0.988246818574322,{"v":5.57194472953837e-05,"d":"5.57E-05"},"*",{"v":1.23166E-5,"d":"1.23E-05"},"ODF3B","NA","NA","NA","K10955//mucin-2;K13171//serine/arginine repetitive matrix protein 1","NP_001014440.2//outer dense fiber protein 3B [Homo sapiens]","3//A2MP1"]
[2113,5228,4.16,8.23,0.984308902280533,{"v":1.36707326500542E-17,"d":"1.37E-17"},"*",{"v":7.89914e-19,"d":"7.90E-19"},"ETS1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription factor complex;GO:0005737//cytoplasm","GO:0000982//transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0008134//transcription factor binding;GO:0003700//DNA binding transcription factor activity;GO:0035035//histone acetyltransferase binding","GO:0045786//negative regulation of cell cycle;GO:0060055//angiogenesis involved in wound healing;GO:0010595//positive regulation of endothelial cell migration;GO:0021854//hypothalamus development;GO:0050728//negative regulation of inflammatory response;GO:0044849//estrous cycle;GO:0046677//response to antibiotic;GO:0061614//pri-miRNA transcription from RNA polymerase II promoter;GO:0032355//response to estradiol;GO:0070555//response to interleukin-1;GO:0021983//pituitary gland development;GO:0045766//positive regulation of angiogenesis;GO:0070301//cellular response to hydrogen peroxide;GO:0008285//negative regulation of cell proliferation;GO:0009612//response to mechanical stimulus;GO:0007565//female pregnancy;GO:0010715//regulation of extracellular matrix disassembly;GO:0001666//response to hypoxia;GO:1904996//positive regulation of leukocyte adhesion to vascular endothelial cell;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045648//positive regulation of erythrocyte differentiation;GO:0050729//positive regulation of inflammatory response;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048870//cell motility;GO:0051272//positive regulation of cellular component movement;GO:0034616//response to laminar fluid shear stress;GO:0030578//PML body organization;GO:0006366//transcription from RNA polymerase II promoter;GO:0045765//regulation of angiogenesis;GO:0006955//immune response;GO:0042981//regulation of apoptotic process;GO:0008284//positive regulation of cell proliferation","K02678//C-ets-1","NP_005229.1//protein C-ets-1 isoform 2 [Homo sapiens];NP_001137292.1//protein C-ets-1 isoform 1 [Homo sapiens];XP_021782433.1//protein C-ets-1 isoform X6 [Papio anubis];XP_006072439.1//PREDICTED: transforming protein p68/c-ets-1 isoform X4 [Bubalus bubalis]","1//3;3//A2MP1"]
[28984,1126,0.44,0.87,0.983511877211431,0.285775997798403,"*",0.1657694,"RGCC","GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005813//centrosome;GO:0005737//cytoplasm","GO:0070412//R-SMAD binding;GO:0030295//protein kinase activator activity;GO:0019901//protein kinase binding","GO:0071456//cellular response to hypoxia;GO:0031659//positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle;GO:0003331//positive regulation of extracellular matrix constituent secretion;GO:0032967//positive regulation of collagen biosynthetic process;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:2000353//positive regulation of endothelial cell apoptotic process;GO:1901203//positive regulation of extracellular matrix assembly;GO:0045840//positive regulation of mitotic nuclear division;GO:0050710//negative regulation of cytokine secretion;GO:0008285//negative regulation of cell proliferation;GO:0001937//negative regulation of endothelial cell proliferation;GO:0006956//complement activation;GO:0072537//fibroblast activation;GO:0071850//mitotic cell cycle arrest;GO:0016525//negative regulation of angiogenesis;GO:0001100//negative regulation of exit from mitosis;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:1901991//negative regulation of mitotic cell cycle phase transition;GO:0010628//positive regulation of gene expression;GO:0051496//positive regulation of stress fiber assembly;GO:0071158//positive regulation of cell cycle arrest;GO:0090272//negative regulation of fibroblast growth factor production;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0051726//regulation of cell cycle;GO:2000573//positive regulation of DNA biosynthetic process;GO:0050715//positive regulation of cytokine secretion;GO:2000048//negative regulation of cell-cell adhesion mediated by cadherin;GO:0043537//negative regulation of blood vessel endothelial cell migration;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest","K05012//chloride channel 3/4/5;K04257//olfactory receptor","NP_054778.2//regulator of cell cycle RGCC [Homo sapiens]","2//1"]
[3903,2733,1.83,3.61,0.980155188603128,{"v":2.17338763359708E-5,"d":"2.17E-05"},"*",{"v":4.47086e-06,"d":"4.47E-06"},"LAIR1","GO:0070062//extracellular exosome;GO:0035579//specific granule membrane;GO:0016021//integral component of membrane;GO:0070821//tertiary granule membrane;GO:0005886//plasma membrane","NA","GO:0043312//neutrophil degranulation;GO:0050776//regulation of immune response;GO:0002250//adaptive immune response","K06725//leukocyte-associated Ig-like receptor","EAW72235.1//leukocyte-associated Ig-like receptor 1, isoform CRA_c, partial [Homo sapiens];NP_068352.2//leukocyte-associated immunoglobulin-like receptor 1 isoform b precursor [Homo sapiens];NP_001275952.2//leukocyte-associated immunoglobulin-like receptor 1 isoform c precursor [Homo sapiens];NP_002278.2//leukocyte-associated immunoglobulin-like receptor 1 isoform a precursor [Homo sapiens];NP_001275954.2//leukocyte-associated immunoglobulin-like receptor 1 isoform e precursor [Homo sapiens]","4;2//1;5"]
[8676,5509,0.34,0.67,0.978626349207433,0.0150432928307107,"*",5.44606E-3,"STX11","GO:0008021//synaptic vesicle;GO:0005794//Golgi apparatus;GO:0031201//SNARE complex;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0000149//SNARE binding;GO:0005484//SNAP receptor activity","GO:0006886//intracellular protein transport;GO:0061025//membrane fusion;GO:0031629//synaptic vesicle fusion to presynaptic active zone membrane;GO:0048278//vesicle docking","K08487//syntaxin 11","XP_011534515.1//PREDICTED: syntaxin-11 isoform X1 [Homo sapiens]","3//A2MP1"]
[330,6932,3.8,7.47,0.975108824458289,{"v":3.16875215529906e-17,"d":"3.17E-17"},"*",{"v":1.89046E-18,"d":"1.89E-18"},"BIRC3","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0045121//membrane raft;GO:0043234//protein complex;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process;GO:0016740//transferase activity;GO:0004842//ubiquitin-protein transferase activity","GO:0034121//regulation of toll-like receptor signaling pathway;GO:0038061//NIK/NF-kappaB signaling;GO:0060544//regulation of necroptotic process;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:2000116//regulation of cysteine-type endopeptidase activity;GO:0007166//cell surface receptor signaling pathway;GO:0007283//spermatogenesis;GO:0010803//regulation of tumor necrosis factor-mediated signaling pathway;GO:0070424//regulation of nucleotide-binding oligomerization domain containing signaling pathway;GO:0016579//protein deubiquitination;GO:1990001//inhibition of cysteine-type endopeptidase activity involved in apoptotic process;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0051291//protein heterooligomerization;GO:0031398//positive regulation of protein ubiquitination;GO:0043066//negative regulation of apoptotic process;GO:0060546//negative regulation of necroptotic process;GO:0045088//regulation of innate immune response;GO:0039535//regulation of RIG-I signaling pathway;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0050727//regulation of inflammatory response;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0042981//regulation of apoptotic process","K16060//baculoviral IAP repeat-containing protein 2/3","NP_001156.1//baculoviral IAP repeat-containing protein 3 [Homo sapiens]","4;2//1"]
[100130370,1200,0.21,0.41,0.965234581839323,0.496162648511256,"*",0.342164,"LOC100130370","NA","NA","NA","K17985//activating molecule in BECN1-regulated autophagy protein 1;K04948//cyclic nucleotide gated channel alpha 1;K01064//wingless-type MMTV integration site family, member 9","XP_011522444.1//PREDICTED: uncharacterized protein LOC100130370 isoform X4 [Homo sapiens]","1//3;2//1"]
[161835,2813,0.21,0.41,0.965234581839323,0.236865272450805,"*",0.1326232,"FSIP1","NA","NA","NA","K12327//caldesmon;K03104//signal recognition particle subunit SRP14;K20478//golgin subfamily B member 1","NP_689810.3//fibrous sheath-interacting protein 1 [Homo sapiens];XP_008015275.1//PREDICTED: fibrous sheath-interacting protein 1 isoform X1 [Chlorocebus sabaeus]","1//3;4"]
[84985,4461,0.21,0.41,0.965234581839323,0.130671499657056,"*",0.0644032,"FAM83A","GO:0005737//cytoplasm","GO:0036312//phosphatidylinositol 3-kinase regulatory subunit binding;GO:0019901//protein kinase binding","GO:0008283//cell proliferation;GO:0007173//epidermal growth factor receptor signaling pathway","K16805//protein FAM83D","NP_001275516.1//protein FAM83A isoform c [Homo sapiens];NP_001308559.1//protein FAM83A isoform d [Homo sapiens];NP_116288.2//protein FAM83A isoform a [Homo sapiens];NP_996889.1//protein FAM83A isoform b [Homo sapiens]","6;1//3;2//1"]
[388524,1578,0.19,0.37,0.961525852185364,0.495757617777778,"*",0.342164,"RPSAP58","GO:0030686//90S preribosome;GO:0005634//nucleus;GO:0022627//cytosolic small ribosomal subunit;GO:0005886//plasma membrane","GO:0005055//laminin receptor activity;GO:0003735//structural constituent of ribosome;GO:0043236//laminin binding","GO:0000028//ribosomal small subunit assembly;GO:0007155//cell adhesion;GO:0006407//rRNA export from nucleus;GO:0000461//endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006412//translation;GO:0000447//endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)","K02998//small subunit ribosomal protein SAe","XP_004835182.2//40S ribosomal protein SA [Heterocephalus glaber]","1//3"]
[7453,2555,65.35,127.04,0.959023676460162,{"v":2.45121767261538e-137,"d":"2.45E-137"},"*",{"v":9.97428e-140,"d":"9.97E-140"},"WARS","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0043234//protein complex;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0004830//tryptophan-tRNA ligase activity;GO:0019904//protein domain specific binding;GO:0005524//ATP binding;GO:0019210//kinase inhibitor activity;GO:0042803//protein homodimerization activity;GO:0019901//protein kinase binding","GO:0001525//angiogenesis;GO:0010835//regulation of protein ADP-ribosylation;GO:0010628//positive regulation of gene expression;GO:0006469//negative regulation of protein kinase activity;GO:0001933//negative regulation of protein phosphorylation;GO:0031334//positive regulation of protein complex assembly;GO:0045765//regulation of angiogenesis;GO:0006418//tRNA aminoacylation for protein translation;GO:0006436//tryptophanyl-tRNA aminoacylation;GO:0006412//translation;GO:0008285//negative regulation of cell proliferation","K01867//tryptophanyl-tRNA synthetase [EC:6.1.1.2]","NP_004175.2//tryptophan--tRNA ligase, cytoplasmic isoform a [Homo sapiens]","1//3;3//A2MP1"]
[3429,652,0.17,0.33,0.956931278108114,0.735476316325777,"*",0.623548,"IFI27","GO:0005637//nuclear inner membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane","GO:0001102//RNA polymerase II activating transcription factor binding;GO:0005521//lamin binding","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0060337//type I interferon signaling pathway;GO:0097190//apoptotic signaling pathway;GO:0046825//regulation of protein export from nucleus;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process","NA","XP_011806935.1//PREDICTED: interferon alpha-inducible protein 27, mitochondrial isoform X1 [Colobus angolensis palliatus]","4;1//3;2//1"]
[6692,2361,0.17,0.33,0.956931278108114,0.344465990080595,"*",0.208698,"SPINT1","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0004867//serine-type endopeptidase inhibitor activity","GO:0060670//branching involved in labyrinthine layer morphogenesis;GO:0045687//positive regulation of glial cell differentiation;GO:0030198//extracellular matrix organization;GO:0001843//neural tube closure;GO:2000178//negative regulation of neural precursor cell proliferation;GO:0071773//cellular response to BMP stimulus;GO:0060674//placenta blood vessel development","K15619//Kunitz-type protease inhibitor 1","NP_003701.1//kunitz-type protease inhibitor 1 isoform 2 precursor [Homo sapiens];NP_857593.1//kunitz-type protease inhibitor 1 isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1;2//1"]
[137075,1972,5.25,10.18,0.95534823352221,{"v":2.8824571392271e-09,"d":"2.88E-09"},"*",{"v":3.40864e-10,"d":"3.41E-10"},"CLDN23","GO:0016021//integral component of membrane;GO:0005923//bicellular tight junction;GO:0005886//plasma membrane","GO:0042802//identical protein binding;GO:0005198//structural molecule activity","GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules","K06087//claudin","NP_919260.2//claudin-23 [Homo sapiens]","2//1"]
[11219,1255,0.97,1.88,0.95467600949051,0.078118285467706,"*",0.0351322,"TREX2","NA","NA","NA","K10791//three prime repair exonuclease 2 [EC:3.1.11.2]","XP_011857628.1//PREDICTED: three prime repair exonuclease 2 [Mandrillus leucophaeus]","3//A2MP1"]
[4207,1978,0.32,0.62,0.954196310386875,0.176900398895426,"*",0.0922376,"BORCS8-MEF2B","GO:0005634//nucleus;GO:0005667//transcription factor complex","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0042826//histone deacetylase binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0046983//protein dimerization activity","GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0007517//muscle organ development","K09261//MADS-box transcription enhancer factor 2B","XP_011720253.1//PREDICTED: myocyte-specific enhancer factor 2B isoform X1 [Macaca nemestrina]","3//A2MP1"]
[3576,1585,9.39,18.18,0.953155136540332,{"v":3.78331275158085e-15,"d":"3.78E-15"},"*",{"v":2.62184e-16,"d":"2.62E-16"},"CXCL8","GO:0005615//extracellular space;GO:0005622//intracellular;GO:0005576//extracellular region","GO:0045236//CXCR chemokine receptor binding;GO:0005153//interleukin-8 receptor binding;GO:0008009//chemokine activity","GO:2000535//regulation of entry of bacterium into host cell;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0050930//induction of positive chemotaxis;GO:0031623//receptor internalization;GO:0042127//regulation of cell proliferation;GO:0034976//response to endoplasmic reticulum stress;GO:0071222//cellular response to lipopolysaccharide;GO:0071356//cellular response to tumor necrosis factor;GO:0071347//cellular response to interleukin-1;GO:0045766//positive regulation of angiogenesis;GO:0008285//negative regulation of cell proliferation;GO:0007165//signal transduction;GO:0001525//angiogenesis;GO:0019722//calcium-mediated signaling;GO:0070098//chemokine-mediated signaling pathway;GO:0031640//killing of cells of other organism;GO:0048566//embryonic digestive tract development;GO:0032496//response to lipopolysaccharide;GO:0035556//intracellular signal transduction;GO:0045744//negative regulation of G-protein coupled receptor protein signaling pathway;GO:0007050//cell cycle arrest;GO:0002237//response to molecule of bacterial origin;GO:0006935//chemotaxis;GO:0030155//regulation of cell adhesion;GO:0007186//G-protein coupled receptor signaling pathway;GO:0042119//neutrophil activation;GO:0030593//neutrophil chemotaxis;GO:0090023//positive regulation of neutrophil chemotaxis;GO:0006954//inflammatory response;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0045091//regulation of single stranded viral RNA replication via double stranded DNA intermediate;GO:0006928//movement of cell or subcellular component;GO:0006955//immune response;GO:0036499//PERK-mediated unfolded protein response","K10030//interleukin 8","NP_000575.1//interleukin-8 isoform 1 precursor [Homo sapiens];NP_001341769.1//interleukin-8 isoform 2 precursor [Homo sapiens]","1//3;3//A2MP1"]
[51265,1588,0.45,0.87,0.951090399519054,0.221462158109658,"*",0.1208656,"CDKL3","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity","GO:0050775//positive regulation of dendrite morphogenesis;GO:0097484//dendrite extension;GO:0006464//cellular protein modification process;GO:0030517//negative regulation of axon extension;GO:0006468//protein phosphorylation","K08824//cyclin-dependent kinase-like [EC:2.7.11.22]","XP_009447950.1//PREDICTED: cyclin-dependent kinase-like 3 isoform X11 [Pan troglodytes];XP_016865026.1//PREDICTED: cyclin-dependent kinase-like 3 isoform X11 [Homo sapiens];XP_016865021.1//PREDICTED: cyclin-dependent kinase-like 3 isoform X6 [Homo sapiens];XP_011541731.1//PREDICTED: cyclin-dependent kinase-like 3 isoform X3 [Homo sapiens];NP_001107047.1//cyclin-dependent kinase-like 3 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[9853,4853,27.74,53.58,0.949726793518776,{"v":4.68615608807339e-89,"d":"4.69E-89"},"*",{"v":3.19764e-91,"d":"3.20E-91"},"RUSC2","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0031410//cytoplasmic vesicle","GO:0017137//Rab GTPase binding","NA","K03006//DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6];K12384//lysosome membrane protein 2;K22016//mucin-3/17","AAH64843.1//RUSC2 protein, partial [Homo sapiens];NP_055621.1//iporin isoform 1 [Homo sapiens]","1//3;4"]
[11147,817,19.14,36.93,0.948202432719588,{"v":4.84267784e-13,"d":"4.84E-13"},"*",{"v":3.94108e-14,"d":"3.94E-14"},"HHLA3","NA","NA","NA","NA","NP_001026863.1//HERV-H LTR-associating protein 3 isoform 1 [Homo sapiens];XP_016804779.1//PREDICTED: HERV-H LTR-associating protein 3, partial [Pan troglodytes]","1//3;2//1"]
[2875,1896,0.42,0.81,0.947532580105865,0.185227842792686,"*",0.097658,"GPT","NA","NA","NA","K00814//alanine transaminase [EC:2.6.1.2]","XP_016815647.1//PREDICTED: alanine aminotransferase 1 isoform X4 [Pan troglodytes]","2//1"]
[333926,1762,0.14,0.27,0.947532580105864,0.496072584498094,"*",0.342164,"PPM1J","NA","GO:0004722//protein serine/threonine phosphatase activity","NA","K17504//protein phosphatase 1J [EC:3.1.3.16]","XP_017725223.1//PREDICTED: protein phosphatase 1J isoform X2 [Rhinopithecus bieti]",5]
[57664,3092,0.56,1.08,0.947532580105864,0.0308508815663982,"*",0.01223104,"PLEKHA4","GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0032266//phosphatidylinositol-3-phosphate binding","GO:0006661//phosphatidylinositol biosynthetic process","K12822//RNA-binding protein 25","NP_065955.2//pleckstrin homology domain-containing family A member 4 isoform 1 [Homo sapiens];NP_001154826.1//pleckstrin homology domain-containing family A member 4 isoform 2 [Homo sapiens]","1//3;2//1"]
[56147,2726,0.14,0.27,0.947532580105864,0.176857930908654,"*",0.0922376,"PCDHA1","NA","NA","NA","K16493//protocadherin alpha","XP_019518209.1//PREDICTED: protocadherin alpha-1 isoform X5 [Hipposideros armiger];XP_011715029.1//PREDICTED: protocadherin alpha-2 [Macaca nemestrina];XP_018882539.1//PREDICTED: protocadherin alpha-10 isoform X13 [Gorilla gorilla gorilla]","3//A2MP1;2//1"]
[197259,2779,7.89,15.21,0.946922947711038,{"v":1.0170178070922E-16,"d":"1.02E-16"},"*",{"v":6.28394e-18,"d":"6.28E-18"},"MLKL","GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0042802//identical protein binding;GO:0004871//signal transducer activity;GO:0019901//protein kinase binding;GO:0032403//protein complex binding","GO:0070266//necroptotic process;GO:0035556//intracellular signal transduction;GO:0070207//protein homotrimerization","K08849//mixed lineage kinase domain-like [EC:2.7.11.1]","NP_001135969.1//mixed lineage kinase domain-like protein isoform 2 [Homo sapiens];NP_689862.1//mixed lineage kinase domain-like protein isoform 1 [Homo sapiens]","3//A2MP1;2//1"]
[1775,1342,1.07,2.06,0.945033540782071,0.0610200358870968,"*",0.0265258,"DNASE1L2","GO:0005634//nucleus;GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0004536//deoxyribonuclease activity;GO:0005509//calcium ion binding;GO:0004519//endonuclease activity","GO:0003335//corneocyte development;GO:0006308//DNA catabolic process;GO:0001942//hair follicle development;GO:0006259//DNA metabolic process","K11995//deoxyribonuclease-1-like protein [EC:3.1.21.-]","XP_011520701.1//PREDICTED: deoxyribonuclease-1-like 2 isoform X1 [Homo sapiens]","1//3;2//1"]
[1435,3964,23.7,45.6,0.944146765266483,{"v":1.07351773495935E-82,"d":"1.07E-82"},"*",{"v":8.2661e-85,"d":"8.27E-85"},"CSF1","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0048471//perinuclear region of cytoplasm;GO:1990682//CSF1-CSF1R complex","GO:0008083//growth factor activity;GO:0005157//macrophage colony-stimulating factor receptor binding;GO:0005125//cytokine activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity","GO:0043687//post-translational protein modification;GO:0010744//positive regulation of macrophage derived foam cell differentiation;GO:0002158//osteoclast proliferation;GO:0030335//positive regulation of cell migration;GO:0032270//positive regulation of cellular protein metabolic process;GO:0030316//osteoclast differentiation;GO:1902228//positive regulation of macrophage colony-stimulating factor signaling pathway;GO:0045672//positive regulation of osteoclast differentiation;GO:1904141//positive regulation of microglial cell migration;GO:0060444//branching involved in mammary gland duct morphogenesis;GO:0044267//cellular protein metabolic process;GO:0060611//mammary gland fat development;GO:0042488//positive regulation of odontogenesis of dentin-containing tooth;GO:0045651//positive regulation of macrophage differentiation;GO:0038145//macrophage colony-stimulating factor signaling pathway;GO:0045087//innate immune response;GO:0030154//cell differentiation;GO:0032946//positive regulation of mononuclear cell proliferation;GO:0010628//positive regulation of gene expression;GO:0060763//mammary duct terminal end bud growth;GO:0001954//positive regulation of cell-matrix adhesion;GO:0003006//developmental process involved in reproduction;GO:0010759//positive regulation of macrophage chemotaxis;GO:0048873//homeostasis of number of cells within a tissue;GO:0010743//regulation of macrophage derived foam cell differentiation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0046579//positive regulation of Ras protein signal transduction;GO:0008283//cell proliferation;GO:0030225//macrophage differentiation;GO:0045860//positive regulation of protein kinase activity;GO:0030097//hemopoiesis;GO:0030278//regulation of ossification;GO:0006954//inflammatory response;GO:0045657//positive regulation of monocyte differentiation;GO:0040018//positive regulation of multicellular organism growth;GO:0042117//monocyte activation;GO:0008284//positive regulation of cell proliferation","K05453//macrophage colony-stimulating factor 1","EAW56418.1//colony stimulating factor 1 (macrophage), isoform CRA_c [Homo sapiens];EAW56417.1//colony stimulating factor 1 (macrophage), isoform CRA_b [Homo sapiens];EAW56421.1//colony stimulating factor 1 (macrophage), isoform CRA_e [Homo sapiens]","3//A2MP1;2//1;5"]
[388284,1287,0.13,0.25,0.943416471633632,0.609297855380976,"*",0.451538,"C16orf86","NA","NA","NA","K06236//collagen, type I, alpha","NP_001013002.2//uncharacterized protein C16orf86 [Homo sapiens]","2//1"]
[360200,3365,0.26,0.5,0.943416471633632,0.15496130246233,"*",0.079188,"TMPRSS9","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane","GO:0004252//serine-type endopeptidase activity","NA","K09640//transmembrane protease serine 9 [EC:3.4.21.-]","NP_892018.1//transmembrane protease serine 9 [Homo sapiens]","2//1"]
[134701,674,0.13,0.25,0.943416471633632,0.732717062821833,"*",0.623548,"RIPPLY2","GO:0005634//nucleus","NA","GO:0010468//regulation of gene expression;GO:0032525//somite rostral/caudal axis specification;GO:0007368//determination of left/right symmetry;GO:0060349//bone morphogenesis;GO:0001503//ossification;GO:0036342//post-anal tail morphogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0009880//embryonic pattern specification;GO:0001756//somitogenesis;GO:0007219//Notch signaling pathway","NA","XP_008967706.1//PREDICTED: protein ripply2 [Pan paniscus]","2//1"]
[9220,2110,7.57,14.53,0.940669497647109,{"v":2.13869547111111e-13,"d":"2.14E-13"},"*",{"v":1.686964E-14,"d":"1.69E-14"},"TIAF1","GO:0005634//nucleus","NA","GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0043066//negative regulation of apoptotic process;GO:0006915//apoptotic process","K10362//myosin XVIII","NP_004731.2//TGFB1-induced anti-apoptotic factor 1 [Homo sapiens]","3//A2MP1"]
[388701,720,0.12,0.23,0.938599455335857,0.735530627086103,"*",0.623548,"C1orf189","NA","NA","NA","NA","XP_001140210.3//PREDICTED: uncharacterized protein C1orf189 homolog [Pan troglodytes]","2//1"]
[3760,4523,0.12,0.23,0.938599455335857,0.285714328398792,"*",0.1657694,"KCNJ3","GO:0030315//T-tubule;GO:0009897//external side of plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex","GO:0086089//voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization;GO:0005242//inward rectifier potassium channel activity;GO:0015467//G-protein activated inward rectifier potassium channel activity;GO:1902282//voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization","GO:0051602//response to electrical stimulus;GO:0006813//potassium ion transport;GO:0099625//ventricular cardiac muscle cell membrane repolarization;GO:0086091//regulation of heart rate by cardiac conduction;GO:0098914//membrane repolarization during atrial cardiac muscle cell action potential;GO:1990573//potassium ion import across plasma membrane;GO:0010107//potassium ion import","K04997//potassium inwardly-rectifying channel subfamily J member 3","OWK00154.1//hypothetical protein Celaphus_00015869 [Cervus elaphus hippelaphus];XP_002918768.1//PREDICTED: G protein-activated inward rectifier potassium channel 1 isoform X1 [Ailuropoda melanoleuca];NP_002230.1//G protein-activated inward rectifier potassium channel 1 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[91977,3493,0.12,0.23,0.938599455335857,0.344537190161224,"*",0.208698,"MYOZ3","GO:0030018//Z disc;GO:0015629//actin cytoskeleton","GO:0003779//actin binding;GO:0051373//FATZ binding;GO:0031433//telethonin binding","GO:0030239//myofibril assembly","K02927//large subunit ribosomal protein L40e;K15696//RING finger protein 113B;K17985//activating molecule in BECN1-regulated autophagy protein 1","NP_588612.2//myozenin-3 [Homo sapiens]","4;2//1"]
[9074,1389,0.12,0.23,0.938599455335857,0.608937780666948,"*",0.451538,"CLDN6","GO:0016327//apicolateral plasma membrane;GO:0016021//integral component of membrane;GO:0005923//bicellular tight junction;GO:0005886//plasma membrane","GO:0042802//identical protein binding;GO:0005198//structural molecule activity;GO:0001618//virus receptor activity","GO:0045216//cell-cell junction organization;GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules","K06087//claudin","XP_021787371.1//claudin-6 [Papio anubis]",4]
[100130827,1270,1.54,2.95,0.937784603554302,0.0220021302968338,"*",0.00835238,"SBK3","NA","GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding","NA","K08858//serine/threonine-protein kinase SBK [EC:2.7.11.1]","NP_001186753.1//uncharacterized serine/threonine-protein kinase SBK3 [Homo sapiens]","2//1"]
[5359,2228,12.47,23.86,0.936132577865558,{"v":1.68366452265023e-22,"d":"1.68E-22"},"*",{"v":6.84048e-24,"d":"6.84E-24"},"PLSCR1","GO:0016020//membrane;GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005887//integral component of plasma membrane;GO:0045121//membrane raft;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane","GO:0003677//DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0005154//epidermal growth factor receptor binding;GO:0042609//CD4 receptor binding;GO:0005509//calcium ion binding;GO:0017128//phospholipid scramblase activity;GO:0017124//SH3 domain binding;GO:0019899//enzyme binding","GO:0035456//response to interferon-beta;GO:0017121//phospholipid scrambling;GO:0045089//positive regulation of innate immune response;GO:0051607//defense response to virus;GO:0006953//acute-phase response;GO:0030168//platelet activation;GO:0010628//positive regulation of gene expression;GO:0006915//apoptotic process;GO:0033003//regulation of mast cell activation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045071//negative regulation of viral genome replication;GO:0006659//phosphatidylserine biosynthetic process;GO:2000373//positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity;GO:0060368//regulation of Fc receptor mediated stimulatory signaling pathway","K06831//galectin-3","NP_066928.1//phospholipid scramblase 1 [Homo sapiens]","2//1"]
[57480,5899,0.34,0.65,0.934904971778115,0.0390650958889058,"*",0.01602564,"PLEKHG1","NA","NA","NA","K20685//guanine nucleotide exchange factor MCF2;K16463//centrosomal protein CEP170;K09610//endothelin-converting enzyme-like 1 [EC:3.4.24.-]","NP_001316727.1//pleckstrin homology domain-containing family G member 1 isoform a [Homo sapiens];XP_011534284.1//PREDICTED: pleckstrin homology domain-containing family G member 1 isoform X3 [Homo sapiens];NP_001316728.1//pleckstrin homology domain-containing family G member 1 isoform b [Homo sapiens];XP_011534283.1//PREDICTED: pleckstrin homology domain-containing family G member 1 isoform X1 [Homo sapiens]","1//3;2//1"]
[440498,766,13.44,25.66,0.932988032310922,{"v":1.72624422529833e-08,"d":"1.73E-08"},"*",{"v":2.26398e-09,"d":"2.26E-09"},"HSBP1L1","NA","GO:0003714//transcription corepressor activity","NA","K19765//heat shock factor-binding protein 1","NP_001129652.1//heat shock factor-binding protein 1-like protein 1 [Homo sapiens]","1//3"]
[1346,783,0.11,0.21,0.932885804141463,0.732932726416483,"*",0.623548,"COX7A1","NA","NA","NA","K02270//cytochrome c oxidase subunit 7a","XP_010367112.1//PREDICTED: uncharacterized protein LOC104666684 [Rhinopithecus roxellana]","3//A2MP1"]
[7805,2240,0.11,0.21,0.932885804141463,0.495802588534107,"*",0.342164,"LAPTM5","GO:0005765//lysosomal membrane;GO:0005887//integral component of plasma membrane;GO:0005764//lysosome","NA","GO:0006810//transport;GO:1990830//cellular response to leukemia inhibitory factor","K12387//lysosomal-associated transmembrane protein","NP_006753.1//lysosomal-associated transmembrane protein 5 [Homo sapiens]","2//1"]
[25907,1876,9.43,18,0.932667230541941,{"v":1.87138648904228e-14,"d":"1.87E-14"},"*",{"v":1.357792E-15,"d":"1.36E-15"},"TMEM158","GO:0016021//integral component of membrane","GO:0042277//peptide binding","NA","K05746//enabled","NP_056259.2//transmembrane protein 158 precursor [Homo sapiens]","2//1"]
[84125,5460,0.1,0.19,0.925999418556223,0.315428033950358,"*",0.1877482,"LRRIQ1","NA","NA","NA","K12484//Rab11 family-interacting protein 1/2/5;K18626//trichohyalin","NP_001073379.1//leucine-rich repeat and IQ domain-containing protein 1 [Homo sapiens]","1//3"]
[79722,2502,0.1,0.19,0.925999418556223,0.495982553176044,"*",0.342164,"ANKRD55","NA","NA","NA","K19626//inversin","NP_078945.2//ankyrin repeat domain-containing protein 55 [Homo sapiens]","2//1"]
[146310,855,0.1,0.19,0.925999418556223,0.732770966821158,"*",0.623548,"RNF151","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0008270//zinc ion binding","GO:0030154//cell differentiation;GO:0007283//spermatogenesis","K11981//E3 ubiquitin-protein ligase NRDP1 [EC:2.3.2.27];K14555//U3 small nucleolar RNA-associated protein 13","NP_777563.2//RING finger protein 151 isoform 1 [Homo sapiens]","1//3;5"]
[285498,2367,0.37,0.7,0.919829651316017,0.595989831407206,"*",0.439064,"RNF212","GO:0000795//synaptonemal complex","GO:0046872//metal ion binding;GO:0019789//SUMO transferase activity;GO:0016874//ligase activity","GO:0007129//synapsis;GO:0006311//meiotic gene conversion;GO:0016925//protein sumoylation;GO:0007131//reciprocal meiotic recombination;GO:0051026//chiasma assembly","NA","NP_001180247.1//probable E3 SUMO-protein ligase RNF212 isoform c [Homo sapiens];NP_919420.1//probable E3 SUMO-protein ligase RNF212 isoform b [Homo sapiens];NP_001124506.1//probable E3 SUMO-protein ligase RNF212 isoform a [Homo sapiens]","4;3//A2MP1;2//1"]
[90353,2107,6.66,12.59,0.918684200647754,{"v":2.61967223153693e-11,"d":"2.62E-11"},"*",{"v":2.46486e-12,"d":"2.46E-12"},"CTU1","GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005737//cytoplasm","GO:0016779//nucleotidyltransferase activity;GO:0000049//tRNA binding;GO:0016740//transferase activity","GO:0002098//tRNA wobble uridine modification;GO:0032447//protein urmylation;GO:0034227//tRNA thio-modification;GO:0006400//tRNA modification","K14168//cytoplasmic tRNA 2-thiolation protein 1 [EC:2.7.7.-]","XP_014979908.1//PREDICTED: cytoplasmic tRNA 2-thiolation protein 1 isoform X1 [Macaca mulatta]","3//A2MP1"]
[50939,8365,0.09,0.17,0.917537839808027,0.221436758160339,"*",0.1208656,"IMPG2","GO:0033165//interphotoreceptor matrix;GO:0016021//integral component of membrane;GO:0043235//receptor complex;GO:0005578//proteinaceous extracellular matrix","GO:0005201//extracellular matrix structural constituent;GO:0008201//heparin binding;GO:0005540//hyaluronic acid binding","GO:0007601//visual perception","K19017//interphotoreceptor matrix proteoglycan 2","NP_057331.2//interphotoreceptor matrix proteoglycan 2 precursor [Homo sapiens]","3//A2MP1"]
[26257,1890,0.72,1.36,0.917537839808027,0.0724817724244554,"*",0.0322842,"NKX2-8","GO:0005634//nucleus","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0003690//double-stranded DNA binding","GO:0030324//lung development;GO:0001889//liver development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0050680//negative regulation of epithelial cell proliferation;GO:0006351//transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter;GO:0007409//axonogenesis","K09347//homeobox protein Nkx-2.8","NP_055175.2//homeobox protein Nkx-2.8 [Homo sapiens]","3//A2MP1"]
[51660,977,2.28,4.3,0.915302835424718,0.01730617847981,"*",0.00638554,"MPC1","GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0031305//integral component of mitochondrial inner membrane","GO:0050833//pyruvate transmembrane transporter activity","GO:1990830//cellular response to leukemia inhibitory factor;GO:0061732//mitochondrial acetyl-CoA biosynthetic process from pyruvate","K22138//mitochondrial pyruvate carrier 1","NP_057182.1//mitochondrial pyruvate carrier 1 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[9080,2139,0.26,0.49,0.914270125974116,0.315461212453981,"*",0.1877482,"CLDN9","GO:0016021//integral component of membrane;GO:0005923//bicellular tight junction;GO:0005886//plasma membrane","GO:0005198//structural molecule activity","NA","K06087//claudin","XP_008694995.1//PREDICTED: claudin-9 [Ursus maritimus]","3//A2MP1"]
[861,6768,4.06,7.62,0.908311270308146,{"v":1.45498722333722E-18,"d":"1.45E-18"},"*",{"v":7.80596e-20,"d":"7.81E-20"},"RUNX1","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0005524//ATP binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0005509//calcium ion binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0008134//transcription factor binding;GO:0003700//DNA binding transcription factor activity;GO:0001047//core promoter binding","GO:2000810//regulation of bicellular tight junction assembly;GO:0030099//myeloid cell differentiation;GO:0048935//peripheral nervous system neuron development;GO:0001503//ossification;GO:0045637//regulation of myeloid cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0001959//regulation of cytokine-mediated signaling pathway;GO:0030853//negative regulation of granulocyte differentiation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0032743//positive regulation of interleukin-2 production;GO:0071425//hematopoietic stem cell proliferation;GO:0050855//regulation of B cell receptor signaling pathway;GO:0045766//positive regulation of angiogenesis;GO:0030097//hemopoiesis;GO:0030182//neuron differentiation;GO:0006351//transcription, DNA-templated;GO:0030111//regulation of Wnt signaling pathway;GO:0033146//regulation of intracellular estrogen receptor signaling pathway;GO:0030854//positive regulation of granulocyte differentiation;GO:0045652//regulation of megakaryocyte differentiation;GO:0045616//regulation of keratinocyte differentiation;GO:0002062//chondrocyte differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:1902036//regulation of hematopoietic stem cell differentiation;GO:0045595//regulation of cell differentiation;GO:0045589//regulation of regulatory T cell differentiation","K08367//runt-related transcription factor 1","NP_001745.2//runt-related transcription factor 1 isoform AML1c [Homo sapiens];CAA56092.1//acute myeloid leukemia gene no 1 [Homo sapiens];NP_001116079.1//runt-related transcription factor 1 isoform AML1a [Homo sapiens]","4;1//3;2//1"]
[6261,15376,0.16,0.3,0.906890595608518,0.0162300542255691,"*",0.00593666,"RYR1","GO:0030315//T-tubule;GO:0005790//smooth endoplasmic reticulum;GO:0070062//extracellular exosome;GO:0031301//integral component of organelle membrane;GO:0005938//cell cortex;GO:0014802//terminal cisterna;GO:1990425//ryanodine receptor complex;GO:0014701//junctional sarcoplasmic reticulum membrane;GO:0030314//junctional membrane complex;GO:0005737//cytoplasm;GO:0016529//sarcoplasmic reticulum;GO:0005887//integral component of plasma membrane;GO:0031674//I band;GO:0033017//sarcoplasmic reticulum membrane;GO:0005886//plasma membrane","GO:0002020//protease binding;GO:0048763//calcium-induced calcium release activity;GO:0005524//ATP binding;GO:0005245//voltage-gated calcium channel activity;GO:0015278//calcium-release channel activity;GO:0005219//ryanodine-sensitive calcium-release channel activity;GO:0005509//calcium ion binding;GO:0005262//calcium channel activity;GO:0005516//calmodulin binding","GO:0014808//release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0043588//skin development;GO:0034220//ion transmembrane transport;GO:0043931//ossification involved in bone maturation;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0071277//cellular response to calcium ion;GO:0031000//response to caffeine;GO:0071313//cellular response to caffeine;GO:1903779//regulation of cardiac conduction;GO:0051289//protein homotetramerization;GO:0006936//muscle contraction;GO:0006816//calcium ion transport;GO:0003151//outflow tract morphogenesis;GO:0048741//skeletal muscle fiber development;GO:0001666//response to hypoxia;GO:0051209//release of sequestered calcium ion into cytosol","K04961//ryanodine receptor 1","NP_001036188.1//ryanodine receptor 1 isoform 2 [Homo sapiens];NP_000531.2//ryanodine receptor 1 isoform 1 [Homo sapiens]","1//3;2//1"]
[56978,3150,0.08,0.15,0.906890595608518,0.666319969782526,"*",0.546646,"PRDM8","NA","NA","NA","K20797//PR domain zinc finger protein 8 [EC:2.1.1.-]","XP_016863957.1//PREDICTED: PR domain zinc finger protein 8 isoform X1 [Homo sapiens]","1//3;3//A2MP1"]
[60489,2529,0.31,0.58,0.903784684740697,0.166995415205529,"*",0.0862158,"APOBEC3G","GO:0030529//intracellular ribonucleoprotein complex;GO:0005829//cytosol;GO:0030895//apolipoprotein B mRNA editing enzyme complex;GO:0000932//P-body;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0047844//deoxycytidine deaminase activity;GO:0008829//dCTP deaminase activity;GO:0042802//identical protein binding;GO:0004126//cytidine deaminase activity;GO:0008270//zinc ion binding;GO:0042803//protein homodimerization activity","GO:0048525//negative regulation of viral process;GO:0051607//defense response to virus;GO:0016032//viral process;GO:0045869//negative regulation of single stranded viral RNA replication via double stranded DNA intermediate;GO:0070383//DNA cytosine deamination;GO:0009972//cytidine deamination;GO:0010529//negative regulation of transposition;GO:0045071//negative regulation of viral genome replication;GO:0045087//innate immune response;GO:0002230//positive regulation of defense response to virus by host;GO:0016553//base conversion or substitution editing","K18750//C->U-editing enzyme APOBEC3 [EC:3.5.4.-]","NP_001336365.1//DNA dC-;NP_001336367.1//DNA dC-;NP_068594.1//DNA dC-","1//3;3//A2MP1"]
[126231,2491,0.44,0.82,0.898120385980786,0.110430474302264,"*",0.0525122,"ZNF573","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","NP_001166161.1//zinc finger protein 573 isoform 3 [Homo sapiens];XP_016881766.1//PREDICTED: zinc finger protein 573 isoform X2 [Homo sapiens];NP_001166162.1//zinc finger protein 573 isoform 4 [Homo sapiens];NP_689573.3//zinc finger protein 573 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[56971,2263,14.85,27.64,0.896294684700131,{"v":1.41047331880492e-24,"d":"1.41E-24"},"*",{"v":5.02416e-26,"d":"5.02E-26"},"CEACAM19","GO:0016021//integral component of membrane","NA","NA","K16825//carcinoembryonic antigen-related cell adhesion molecule 19","NP_064604.2//carcinoembryonic antigen-related cell adhesion molecule 19 isoform 2 precursor [Homo sapiens];NP_001121365.1//carcinoembryonic antigen-related cell adhesion molecule 19 isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[6515,3938,5.49,10.2,0.893691097853659,{"v":3.68483654563297e-16,"d":"3.68E-16"},"*",{"v":2.3506e-17,"d":"2.35E-17"},"SLC2A3","GO:0016021//integral component of membrane","GO:0005355//glucose transmembrane transporter activity","NA","K08142//MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 3","XP_002752353.3//PREDICTED: solute carrier family 2, facilitated glucose transporter member 3 [Callithrix jacchus]","2//1"]
[80853,9178,0.21,0.39,0.893084796083488,0.0403349445055446,"*",0.01662232,"KDM7A","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus","GO:0035575//histone demethylase activity (H4-K20 specific);GO:0005506//iron ion binding;GO:0035064//methylated histone binding;GO:0032452//histone demethylase activity;GO:0051864//histone demethylase activity (H3-K36 specific);GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;GO:0008270//zinc ion binding;GO:0032454//histone demethylase activity (H3-K9 specific);GO:0071558//histone demethylase activity (H3-K27 specific)","GO:0030901//midbrain development;GO:0035574//histone H4-K20 demethylation;GO:0033169//histone H3-K9 demethylation;GO:0071557//histone H3-K27 demethylation;GO:0006351//transcription, DNA-templated;GO:0070544//histone H3-K36 demethylation;GO:0045893//positive regulation of transcription, DNA-templated","K11445//lysine-specific demethylase 7A [EC:1.14.11.-]","NP_085150.1//lysine-specific demethylase 7A [Homo sapiens]","1//3"]
[100820829,2355,0.28,0.52,0.893084796083488,0.262596199715505,"*",0.1502358,"MYZAP","GO:0005622//intracellular","NA","GO:0035556//intracellular signal transduction","K22031//myocardial zonula adherens protein","NP_689664.3//myocardial zonula adherens protein isoform 2 [Homo sapiens];XP_012298454.1//myocardial zonula adherens protein isoform X1 [Aotus nancymaae]","4;7"]
[100288695,1221,0.07,0.13,0.893084796083488,0.732986662153212,"*",0.623548,"LIMS4","GO:0005737//cytoplasm","GO:0046872//metal ion binding","NA","NA","NP_277049.1//LIM and senescent cell antigen-like-containing domain protein 3 [Homo sapiens]","1//3"]
[57576,4000,0.28,0.52,0.893084796083488,0.121596952474734,"*",0.0587508,"KIF17","GO:0030992//intraciliary transport particle B;GO:0005929//cilium;GO:0032839//dendrite cytoplasm;GO:0005874//microtubule;GO:0032391//photoreceptor connecting cilium;GO:0036064//ciliary basal body;GO:1990075//periciliary membrane compartment;GO:0005829//cytosol;GO:0005930//axoneme;GO:0005871//kinesin complex","GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0008574//ATP-dependent microtubule motor activity, plus-end-directed","GO:0022008//neurogenesis;GO:0007018//microtubule-based movement;GO:0035735//intraciliary transport involved in cilium assembly;GO:0098971//anterograde dendritic transport of neurotransmitter receptor complex;GO:0030030//cell projection organization;GO:0016192//vesicle-mediated transport","K20198//kinesin family member 17","NP_065867.2//kinesin-like protein KIF17 isoform a [Homo sapiens];NP_001116291.1//kinesin-like protein KIF17 isoform b [Homo sapiens]","1//3;3//A2MP1;2//1"]
[25819,1984,6.33,11.74,0.891155003681711,{"v":1.30972932461538E-9,"d":"1.31E-09"},"*",{"v":1.492242E-10,"d":"1.49E-10"},"NOCT","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000932//P-body;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm","GO:0004535//poly(A)-specific ribonuclease activity;GO:0003729//mRNA binding;GO:0046872//metal ion binding;GO:0003700//DNA binding transcription factor activity","GO:0006397//mRNA processing;GO:0007623//circadian rhythm;GO:0009991//response to extracellular stimulus;GO:0045995//regulation of embryonic development;GO:0045600//positive regulation of fat cell differentiation;GO:0032496//response to lipopolysaccharide;GO:0010629//negative regulation of gene expression;GO:0000290//deadenylation-dependent decapping of nuclear-transcribed mRNA;GO:0006366//transcription from RNA polymerase II promoter;GO:0042752//regulation of circadian rhythm;GO:0045668//negative regulation of osteoblast differentiation;GO:0033962//cytoplasmic mRNA processing body assembly;GO:0032922//circadian regulation of gene expression;GO:0048255//mRNA stabilization","K18764//nocturnin [EC:3.1.13.4]","NP_036250.2//nocturnin [Homo sapiens]","3//A2MP1"]
[80741,738,0.8,1.48,0.887525270741587,0.31536169787592,"*",0.1877482,"LY6G5C","GO:0009897//external side of plasma membrane;GO:0043234//protein complex;GO:0016021//integral component of membrane;GO:0005576//extracellular region","GO:0042802//identical protein binding","GO:0051260//protein homooligomerization","K20005//lymphocyte antigen 6 complex locus protein G5","NP_079538.3//lymphocyte antigen 6 complex locus protein G5c precursor [Homo sapiens]","3//A2MP1"]
[2826,1244,0.46,0.85,0.885828980080689,0.315394862425071,"*",0.1877482,"CCR10","GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0016493//C-C chemokine receptor activity;GO:0004930//G-protein coupled receptor activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0006955//immune response;GO:0006935//chemotaxis","K04185//C-C chemokine receptor type 10","NP_057686.2//C-C chemokine receptor type 10 [Homo sapiens]","2//1"]
[389692,2373,0.13,0.24,0.884522782580064,0.540203744762906,"*",0.385826,"MAFA","GO:0005634//nucleus","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0009749//response to glucose;GO:0007263//nitric oxide mediated signal transduction;GO:0030073//insulin secretion;GO:0045893//positive regulation of transcription, DNA-templated","K21125//mucin-5AC","NP_919331.1//transcription factor MafA [Mus musculus]","3//A2MP1"]
[147746,2501,0.26,0.48,0.884522782580064,0.262624936441234,"*",0.1502358,"HIPK4","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity","GO:1901796//regulation of signal transduction by p53 class mediator;GO:0018105//peptidyl-serine phosphorylation;GO:0016572//histone phosphorylation;GO:0046777//protein autophosphorylation","K08826//homeodomain interacting protein kinase [EC:2.7.11.1]","NP_653286.2//homeodomain-interacting protein kinase 4 [Homo sapiens]",4]
[196051,1354,0.13,0.24,0.884522782580064,0.608834980332574,"*",0.451538,"PLPP4","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0042802//identical protein binding;GO:0008195//phosphatidate phosphatase activity","GO:0007165//signal transduction;GO:0046839//phospholipid dephosphorylation;GO:0006644//phospholipid metabolic process;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis","K18693//diacylglycerol diphosphate phosphatase / phosphatidate phosphatase [EC:3.1.3.81 3.1.3.4]","NP_001305098.1//phospholipid phosphatase 4 isoform e [Homo sapiens];NP_001305095.1//phospholipid phosphatase 4 isoform b [Homo sapiens];XP_001496078.4//PREDICTED: phosphatidate phosphatase PPAPDC1A [Equus caballus];XP_010363972.1//PREDICTED: phosphatidate phosphatase PPAPDC1A [Rhinopithecus roxellana];NP_001305096.1//phospholipid phosphatase 4 isoform c [Homo sapiens]","1//3;2//1"]
[1890,1714,8.56,15.8,0.884241856663318,{"v":9.81489489265537e-11,"d":"9.81E-11"},"*",{"v":9.78786e-12,"d":"9.79E-12"},"TYMP","GO:0005829//cytosol","GO:0016763//transferase activity, transferring pentosyl groups;GO:0016154//pyrimidine-nucleoside phosphorylase activity;GO:0008083//growth factor activity;GO:0009032//thymidine phosphorylase activity;GO:0042803//protein homodimerization activity;GO:0004645//phosphorylase activity","GO:0051969//regulation of transmission of nerve impulse;GO:0046135//pyrimidine nucleoside catabolic process;GO:0030154//cell differentiation;GO:0001525//angiogenesis;GO:0031641//regulation of myelination;GO:0043097//pyrimidine nucleoside salvage;GO:0006213//pyrimidine nucleoside metabolic process;GO:1905333//regulation of gastric motility;GO:0000002//mitochondrial genome maintenance;GO:0006935//chemotaxis;GO:0006206//pyrimidine nucleobase metabolic process","K00758//thymidine phosphorylase [EC:2.4.2.4]","XP_017360425.1//PREDICTED: thymidine phosphorylase isoform X2 [Cebus capucinus imitator];NP_001944.1//thymidine phosphorylase isoform 1 precursor [Homo sapiens];NP_001244918.1//thymidine phosphorylase isoform 2 [Homo sapiens]","4;1//3;2//1"]
[5329,1554,19.23,35.45,0.882426864786981,{"v":2.17896830691489e-20,"d":"2.18E-20"},"*",{"v":1.025782e-21,"d":"1.03E-21"},"PLAUR","GO:0070062//extracellular exosome;GO:0005788//endoplasmic reticulum lumen;GO:0005925//focal adhesion;GO:0019898//extrinsic component of membrane;GO:0030054//cell junction;GO:0031225//anchored component of membrane;GO:0071438//invadopodium membrane;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0035579//specific granule membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane","GO:0019904//protein domain specific binding;GO:0004872//receptor activity;GO:0030377//urokinase plasminogen activator receptor activity;GO:0005102//receptor binding;GO:0019899//enzyme binding","GO:0042730//fibrinolysis;GO:0007165//signal transduction;GO:0007596//blood coagulation;GO:0038195//urokinase plasminogen activator signaling pathway;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway;GO:2001268//negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0016255//attachment of GPI anchor to protein;GO:0006928//movement of cell or subcellular component;GO:0030162//regulation of proteolysis;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0001934//positive regulation of protein phosphorylation;GO:0043312//neutrophil degranulation;GO:0045742//positive regulation of epidermal growth factor receptor signaling pathway;GO:0006935//chemotaxis;GO:0043388//positive regulation of DNA binding","K03985//plasminogen activator, urokinase receptor","NP_001005377.1//urokinase plasminogen activator surface receptor isoform 3 precursor [Homo sapiens];NP_001287966.1//urokinase plasminogen activator surface receptor isoform 4 precursor [Homo sapiens];NP_002650.1//urokinase plasminogen activator surface receptor isoform 1 precursor [Homo sapiens];NP_001005376.1//urokinase plasminogen activator surface receptor isoform 2 precursor [Homo sapiens]","1//3;3//A2MP1;2//1"]
[115361,6160,0.83,1.53,0.882348411345727,0.000244843879281558,"*",{"v":6.05902e-05,"d":"6.06E-05"},"GBP4","GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0000139//Golgi membrane","GO:0005525//GTP binding;GO:0003924//GTPase activity","NA","K20899//guanylate-binding protein 1/3/4/7","NP_443173.2//guanylate-binding protein 4 [Homo sapiens]",4]
[10906,2753,11.14,20.53,0.88198439476857,{"v":1.76706045244957e-21,"d":"1.77E-21"},"*",{"v":7.6771e-23,"d":"7.68E-23"},"TRAFD1","NA","GO:0046872//metal ion binding","GO:0045824//negative regulation of innate immune response;GO:0034097//response to cytokine","NA","NP_006691.1//TRAF-type zinc finger domain-containing protein 1 [Homo sapiens]","1//3;2//1"]
[161582,1811,9.69,17.85,0.881355503501381,{"v":1.43423598727811e-12,"d":"1.43E-12"},"*",{"v":1.213902e-13,"d":"1.21E-13"},"DNAAF4","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005813//centrosome;GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0097730//non-motile cilium","GO:0030331//estrogen receptor binding","GO:0003341//cilium movement;GO:0001764//neuron migration;GO:0007368//determination of left/right symmetry;GO:0036159//inner dynein arm assembly;GO:0033146//regulation of intracellular estrogen receptor signaling pathway;GO:0036158//outer dynein arm assembly;GO:0061136//regulation of proteasomal protein catabolic process","K19758//dyslexia susceptibility 1 candidate gene 1 protein","XP_011948424.1//PREDICTED: dyslexia susceptibility 1 candidate gene 1 protein isoform X1 [Cercocebus atys];XP_010370873.1//PREDICTED: dyslexia susceptibility 1 candidate gene 1 protein isoform X3 [Rhinopithecus roxellana];XP_010370872.1//PREDICTED: dyslexia susceptibility 1 candidate gene 1 protein isoform X2 [Rhinopithecus roxellana]","1//3;3//A2MP1;2//1"]
[163154,1407,6.17,11.36,0.880620440355264,{"v":1.14172853701493e-06,"d":"1.14E-06"},"*",{"v":1.915508e-07,"d":"1.92E-07"},"PRR22","NA","NA","NA","K19719//collagen, type II, alpha;K16483//centrosomal protein POC5;K05544//tRNA-dihydrouridine synthase 3 [EC:1.3.1.89];K19720//collagen, type III, alpha","XP_004059883.2//PREDICTED: proline-rich protein 22 [Gorilla gorilla gorilla]","1//3"]
[10437,1034,20.28,37.2,0.875244968992053,{"v":1.71814245427831E-14,"d":"1.72E-14"},"*",{"v":1.244454E-15,"d":"1.24E-15"},"IFI30","GO:0043231//intracellular membrane-bounded organelle;GO:0005829//cytosol;GO:0043202//lysosomal lumen;GO:0005576//extracellular region;GO:0030054//cell junction;GO:0005764//lysosome","GO:0016667//oxidoreductase activity, acting on a sulfur group of donors","GO:0060333//interferon-gamma-mediated signaling pathway;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II","K08059//interferon, gamma-inducible protein 30","AAF04618.1//gamma-interferon inducible lysosomal thiol reductase [Homo sapiens]",4]
[22987,7442,0.36,0.66,0.874469117916141,0.955412686238532,"*",0.912708,"SV2C","GO:0008021//synaptic vesicle;GO:0016021//integral component of membrane","GO:0022857//transmembrane transporter activity","NA","K06258//MFS transporter, VNT family, synaptic vesicle glycoprotein 2","XP_008961059.1//PREDICTED: synaptic vesicle glycoprotein 2C isoform X2 [Pan paniscus];XP_011944649.1//PREDICTED: synaptic vesicle glycoprotein 2C isoform X1 [Cercocebus atys]","1//3;3//A2MP1"]
[392255,3714,0.06,0.11,0.874469117916141,0.629341514835293,"*",0.505908,"GDF6","GO:0005615//extracellular space;GO:0005576//extracellular region","GO:0008083//growth factor activity;GO:0005125//cytokine activity;GO:0005160//transforming growth factor beta receptor binding;GO:0042803//protein homodimerization activity","GO:0045666//positive regulation of neuron differentiation;GO:0043408//regulation of MAPK cascade;GO:0030509//BMP signaling pathway;GO:0032924//activin receptor signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0032332//positive regulation of chondrocyte differentiation;GO:0006915//apoptotic process;GO:0060395//SMAD protein signal transduction;GO:1900745//positive regulation of p38MAPK cascade;GO:1990009//retinal cell apoptotic process;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0045444//fat cell differentiation;GO:0060389//pathway-restricted SMAD protein phosphorylation;GO:0042981//regulation of apoptotic process;GO:0048468//cell development","K20012//growth differentiation factor 6","NP_001001557.1//growth/differentiation factor 6 preproprotein [Homo sapiens]","3//A2MP1"]
[114900,1436,0.06,0.11,0.874469117916141,0.735747950361944,"*",0.623548,"C1QTNF4","NA","NA","NA","K06237//collagen, type IV, alpha;K13172//serine/arginine repetitive matrix protein 2","XP_007997484.1//PREDICTED: complement C1q tumor necrosis factor-related protein 4 [Chlorocebus sabaeus]","2//1"]
[57699,1818,0.06,0.11,0.874469117916141,0.732950721160185,"*",0.626454,"CPNE5","GO:0070062//extracellular exosome;GO:0043025//neuronal cell body;GO:0043204//perikaryon;GO:0043005//neuron projection","NA","GO:1903861//positive regulation of dendrite extension","K16280//E3 ubiquitin-protein ligase RGLG [EC:2.3.2.27];K11348//bromodomain and PHD finger-containing protein 1;K20493//leucine-rich repeat-containing protein 16","XP_018885026.1//PREDICTED: copine-5 isoform X3 [Gorilla gorilla gorilla];XP_016008139.1//PREDICTED: copine-5 isoform X13 [Rousettus aegyptiacus];NP_065990.1//copine-5 isoform a [Homo sapiens]","1//3"]
[326340,1467,0.06,0.11,0.874469117916141,0.734500092323575,"*",0.623548,"ZAR1","GO:0005737//cytoplasm","NA","GO:0007275//multicellular organism development","K18762//zygote arrest protein 1","NP_783318.1//zygote arrest protein 1 [Homo sapiens]","2//1"]
[9715,4285,0.06,0.11,0.874469117916141,0.495847567449878,"*",0.342164,"FAM131B","GO:0005654//nucleoplasm;GO:0005829//cytosol","NA","NA","K03260//translation initiation factor 4G;K05010//chloride channel 1, skeletal muscle","NP_001026860.2//protein FAM131B isoform a [Homo sapiens]","1//3;4;2//1"]
[55337,2147,8.15,14.94,0.874308183670797,{"v":1.69216810411765e-12,"d":"1.69E-12"},"*",{"v":1.440684E-13,"d":"1.44E-13"},"C19orf66","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0003723//RNA binding","GO:0034340//response to type I interferon;GO:0034341//response to interferon-gamma;GO:0045071//negative regulation of viral genome replication;GO:0034342//response to type III interferon;GO:0051607//defense response to virus","K07603//collagen, type XVII, alpha;K06274//vasodilator-stimulated phosphoprotein","NP_060851.2//repressor of yield of DENV protein isoform 1 [Homo sapiens];NP_001295206.1//repressor of yield of DENV protein isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[6339,3063,0.88,1.61,0.87148525947732,0.0116542848318804,"*",0.00410096,"SCNN1D","GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0015629//actin cytoskeleton;GO:0005886//plasma membrane","GO:0015280//ligand-gated sodium channel activity","GO:0050909//sensory perception of taste;GO:0034220//ion transmembrane transport;GO:0050896//response to stimulus;GO:0006814//sodium ion transport","K04826//amiloride-sensitive sodium channel subunit delta","NP_001123885.2//amiloride-sensitive sodium channel subunit delta [Homo sapiens]","3//A2MP1"]
[56114,4602,0.17,0.31,0.866733469136536,0.240106335,"*",0.1346784,"PCDHGA1","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005509//calcium ion binding","GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules","K16495//protocadherin gamma subfamily A","XP_010336467.1//PREDICTED: protocadherin gamma-A1 isoform X9 [Saimiri boliviensis boliviensis];XP_002816053.1//PREDICTED: protocadherin gamma-A1 [Pongo abelii]","1//3;2//1"]
[283869,1033,0.96,1.75,0.866248611111173,0.170587200338042,"*",0.0884546,"NPW","NA","NA","NA","K20655//Rho GTPase-activating protein SYDE;K19475//WAS/WASL-interacting protein;K05267//preproneuropeptide B","EAW85567.1//hCG1817523, isoform CRA_a, partial [Homo sapiens]","2//1"]
[83858,2530,1.87,3.4,0.862496476250065,0.000769019891000687,"*",0.000210236,"ATAD3B","GO:0030667//secretory granule membrane;GO:0101003//ficolin-1-rich granule membrane;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0005886//plasma membrane","GO:0005524//ATP binding","GO:0043312//neutrophil degranulation","K17681//ATPase family AAA domain-containing protein 3A/B","NP_114127.3//ATPase family AAA domain-containing protein 3B isoform AAA-TOB3l [Homo sapiens];BAA86587.1//KIAA1273 protein, partial [Homo sapiens]","1//3;5"]
[11148,2679,0.66,1.2,0.862496476250065,0.0519436728395062,"*",0.022125,"HHLA2","GO:0016021//integral component of membrane","NA","GO:0031295//T cell costimulation;GO:0001819//positive regulation of cytokine production;GO:0042104//positive regulation of activated T cell proliferation","K06747//immune costimulatory protein B7-H4;K06746//immune costimulatory protein B7-H3","NP_009003.1//HERV-H LTR-associating protein 2 isoform a precursor [Homo sapiens];NP_001269488.1//HERV-H LTR-associating protein 2 isoform c [Homo sapiens];NP_001269487.1//HERV-H LTR-associating protein 2 isoform b precursor [Homo sapiens]","1//3;3//A2MP1"]
[113802,1724,1.51,2.74,0.859627343635448,0.0162328323930161,"*",0.00593666,"HENMT1","GO:0043186//P granule","GO:0003723//RNA binding;GO:0046872//metal ion binding;GO:0008171//O-methyltransferase activity;GO:0008173//RNA methyltransferase activity","GO:0001510//RNA methylation;GO:0031047//gene silencing by RNA;GO:0034587//piRNA metabolic process","K20798//small RNA 2'-O-methyltransferase [EC:2.1.1.-]","XP_015001814.1//PREDICTED: small RNA 2'-O-methyltransferase isoform X1 [Macaca mulatta];NP_653185.2//small RNA 2'-O-methyltransferase [Homo sapiens]","1//3;2//1"]
[266727,8907,2.26,4.1,0.859301137090258,{"v":6.57192393103448e-14,"d":"6.57E-14"},"*",{"v":5.01102e-15,"d":"5.01E-15"},"MDGA1","GO:0016020//membrane;GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0046658//anchored component of plasma membrane;GO:0005886//plasma membrane","NA","GO:0006501//C-terminal protein lipidation;GO:0001764//neuron migration;GO:0007420//brain development;GO:0021527//spinal cord association neuron differentiation","K17341//hemicentin","NP_705691.1//MAM domain-containing glycosylphosphatidylinositol anchor protein 1 preproprotein [Homo sapiens]","3//A2MP1"]
[170961,4041,0.16,0.29,0.857980995127572,0.262653679457152,"*",0.1502358,"ANKRD24","NA","NA","NA","K16628//collagen, type VII, alpha","XP_011526059.1//PREDICTED: ankyrin repeat domain-containing protein 24 isoform X1 [Homo sapiens]","1//3"]
[113278,2716,0.21,0.38,0.855610090664825,0.315328540300704,"*",0.1877482,"SLC52A3","GO:0005887//integral component of plasma membrane;GO:0016324//apical plasma membrane;GO:0005886//plasma membrane","GO:0032217//riboflavin transmembrane transporter activity","GO:0006771//riboflavin metabolic process;GO:0007605//sensory perception of sound;GO:0032218//riboflavin transport;GO:0034605//cellular response to heat","K14620//riboflavin transporter 2","XP_007961150.1//PREDICTED: solute carrier family 52, riboflavin transporter, member 3 isoform X1 [Chlorocebus sabaeus]","3//A2MP1"]
[92840,1553,6.2,11.19,0.851869915702156,{"v":7.20011570844582e-07,"d":"7.20E-07"},"*",{"v":1.168768E-7,"d":"1.17E-07"},"REEP6","GO:0044317//rod spherule;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0001917//photoreceptor inner segment;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0045177//apical part of cell","NA","GO:0032386//regulation of intracellular transport;GO:0050908//detection of light stimulus involved in visual perception","K17279//receptor expression-enhancing protein 5/6","EHH29425.1//hypothetical protein EGK_09851, partial [Macaca mulatta]","3//A2MP1;2//1"]
[5098,2924,3.44,6.2,0.84985965057214,6.202398056926E-3,"*",2.04624E-3,"PCDHGC3","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005509//calcium ion binding","GO:0007399//nervous system development;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007267//cell-cell signaling;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules","K16493//protocadherin alpha;K16496//protocadherin gamma subfamily B;K16497//protocadherin gamma subfamily C;K16495//protocadherin gamma subfamily A","NP_002579.2//protocadherin gamma-C3 isoform 1 precursor [Homo sapiens];NP_115778.1//protocadherin gamma-C3 isoform 2 precursor [Homo sapiens];XP_012360269.1//PREDICTED: protocadherin gamma-B5 isoform X17 [Nomascus leucogenys]","1//3;3//A2MP1;2//1"]
[344658,2387,0.05,0.09,0.84799690655495,0.735856660165485,"*",0.623548,"SAMD7","GO:0005634//nucleus;GO:0005737//cytoplasm","NA","NA","K11457//polyhomeotic-like protein 2","NP_872416.1//sterile alpha motif domain-containing protein 7 [Homo sapiens]","1//3;3//A2MP1"]
[147948,3150,0.1,0.18,0.84799690655495,0.540014415491107,"*",0.385826,"ZNF582","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_012027239.2//PREDICTED: zinc finger protein 582 isoform X2 [Ovis aries musimon];XP_008526872.1//PREDICTED: zinc finger protein 582 isoform X1 [Equus przewalskii]","1//3;2//1"]
[8048,1464,0.05,0.09,0.84799690655495,0.647881759427828,"*",0.499032,"CSRP3","GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0030018//Z disc","GO:0003779//actin binding;GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0008307//structural constituent of muscle;GO:0031433//telethonin binding;GO:0042805//actinin binding","GO:1903919//negative regulation of actin filament severing;GO:0048738//cardiac muscle tissue development;GO:0006351//transcription, DNA-templated;GO:0003300//cardiac muscle hypertrophy;GO:0002026//regulation of the force of heart contraction;GO:0045662//negative regulation of myoblast differentiation;GO:0033365//protein localization to organelle;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0060048//cardiac muscle contraction;GO:0045663//positive regulation of myoblast differentiation;GO:1903920//positive regulation of actin filament severing;GO:0007519//skeletal muscle tissue development;GO:0006874//cellular calcium ion homeostasis;GO:0055003//cardiac myofibril assembly;GO:0035995//detection of muscle stretch","K09377//cysteine and glycine-rich protein","XP_010985770.1//PREDICTED: cysteine and glycine-rich protein 3 isoform X2 [Camelus dromedarius]",4]
[56171,12408,0.05,0.09,0.84799690655495,0.34416949369183,"*",0.208346,"DNAH7","NA","NA","NA","K10408//dynein heavy chain, axonemal","XP_005573852.1//PREDICTED: dynein heavy chain 7, axonemal isoform X1 [Macaca fascicularis]","2//1"]
[11181,1781,0.05,0.09,0.84799690655495,0.732339956767885,"*",0.623548,"TREH","GO:0070062//extracellular exosome;GO:0046658//anchored component of plasma membrane;GO:0005886//plasma membrane","GO:0004555//alpha,alpha-trehalase activity","GO:0009887//animal organ morphogenesis;GO:0005993//trehalose catabolic process;GO:0005991//trehalose metabolic process","K01194//alpha,alpha-trehalase [EC:3.2.1.28]","NP_001287994.1//trehalase isoform 2 precursor [Homo sapiens];NP_009111.2//trehalase isoform 1 precursor [Homo sapiens]","1//3;2//1"]
[3770,2851,0.84,1.51,0.846087316546319,0.0225949421557673,"*",0.00860854,"KCNJ14","GO:0030425//dendrite;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0043025//neuronal cell body","GO:0005242//inward rectifier potassium channel activity","GO:0061337//cardiac conduction;GO:0010107//potassium ion import","K05007//potassium inwardly-rectifying channel subfamily J member 14","NP_037480.1//ATP-sensitive inward rectifier potassium channel 14 [Homo sapiens]","3//A2MP1"]
[4092,2849,12.31,22.07,0.842255867795157,{"v":3.52808633820459e-17,"d":"3.53E-17"},"*",{"v":2.11588e-18,"d":"2.12E-18"},"SMAD7","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005622//intracellular;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0016342//catenin complex;GO:0005913//cell-cell adherens junction;GO:0005667//transcription factor complex;GO:0005829//cytosol;GO:0043234//protein complex;GO:0001650//fibrillar center;GO:0005886//plasma membrane","GO:0030617//transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity;GO:0003677//DNA binding;GO:0048185//activin binding;GO:0031625//ubiquitin protein ligase binding;GO:0044212//transcription regulatory region DNA binding;GO:0046872//metal ion binding;GO:0005518//collagen binding;GO:0070411//I-SMAD binding;GO:0003700//DNA binding transcription factor activity;GO:0034713//type I transforming growth factor beta receptor binding;GO:0008013//beta-catenin binding","GO:0051444//negative regulation of ubiquitin-protein transferase activity;GO:0060412//ventricular septum morphogenesis;GO:0010717//regulation of epithelial to mesenchymal transition;GO:0043433//negative regulation of DNA binding transcription factor activity;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0017015//regulation of transforming growth factor beta receptor signaling pathway;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0016579//protein deubiquitination;GO:0002725//negative regulation of T cell cytokine production;GO:0032925//regulation of activin receptor signaling pathway;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0034629//cellular protein complex localization;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0055117//regulation of cardiac muscle contraction;GO:0030509//BMP signaling pathway;GO:2000320//negative regulation of T-helper 17 cell differentiation;GO:1990830//cellular response to leukemia inhibitory factor;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0060394//negative regulation of pathway-restricted SMAD protein phosphorylation;GO:0010801//negative regulation of peptidyl-threonine phosphorylation;GO:0030514//negative regulation of BMP signaling pathway;GO:0031397//negative regulation of protein ubiquitination;GO:0010944//negative regulation of transcription by competitive promoter binding;GO:0006355//regulation of transcription, DNA-templated;GO:0022409//positive regulation of cell-cell adhesion;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:2000317//negative regulation of T-helper 17 type immune response;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0034616//response to laminar fluid shear stress;GO:0031398//positive regulation of protein ubiquitination;GO:0006351//transcription, DNA-templated;GO:0030336//negative regulation of cell migration;GO:0060373//regulation of ventricular cardiac muscle cell membrane depolarization;GO:0034333//adherens junction assembly;GO:0048844//artery morphogenesis;GO:0060389//pathway-restricted SMAD protein phosphorylation;GO:0001657//ureteric bud development;GO:0050821//protein stabilization","K19631//mothers against decapentaplegic homolog 7","EDL82858.1//MAD homolog 7 (Drosophila), isoform CRA_a [Rattus norvegicus];NP_001177752.1//mothers against decapentaplegic homolog 7 isoform 4 [Homo sapiens];XP_012657553.1//PREDICTED: mothers against decapentaplegic homolog 7 isoform X1 [Otolemur garnettii]","1//3;3//A2MP1"]
[4902,1139,0.72,1.29,0.841302253980942,0.240133135573167,"*",0.1346784,"NRTN","GO:0030424//axon;GO:0005622//intracellular;GO:0005576//extracellular region","GO:0008083//growth factor activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005102//receptor binding","GO:0007399//nervous system development;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0021675//nerve development;GO:0000165//MAPK cascade;GO:0001755//neural crest cell migration;GO:0031175//neuron projection development;GO:0007411//axon guidance","K05452//glial cell derived neurotrophic factor","NP_004549.1//neurturin preproprotein [Homo sapiens]",4]
[414235,2224,0.24,0.43,0.841302253980942,0.402966085529491,"*",0.26132,"PRR26","NA","NA","NA","NA","NP_001342319.1//proline-rich protein 26 isoform 4 [Homo sapiens];NP_001342318.1//proline-rich protein 26 isoform 3 [Homo sapiens];NP_001342317.1//proline-rich protein 26 isoform 2 [Homo sapiens];NP_001342316.1//proline-rich protein 26 isoform 1 [Homo sapiens]","1//3"]
[100462983,1383,4.59,8.22,0.840644240267875,0.000101015251427018,"*",{"v":2.3265e-05,"d":"2.33E-05"},"MTRNR2L3","NA","NA","NA","K22237//Rab effector MyRIP","XP_012365851.1//PREDICTED: rab effector MyRIP [Nomascus leucogenys]","1//3"]
[123264,940,1.67,2.99,0.840297381724053,0.0863985803556772,"*",0.0395376,"SLC51B","NA","NA","NA","K14361//organic solute transporter subunit beta","XP_018866857.1//PREDICTED: organic solute transporter subunit beta isoform X1 [Gorilla gorilla gorilla]","3//A2MP1"]
[4924,2585,83.41,149.29,0.839825268194443,{"v":9.11411617971014e-134,"d":"9.11E-134"},"*",{"v":3.93686E-136,"d":"3.94E-136"},"NUCB1","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005788//endoplasmic reticulum lumen;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0032580//Golgi cisterna membrane;GO:0005791//rough endoplasmic reticulum;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005802//trans-Golgi network;GO:0005801//cis-Golgi network;GO:0005798//Golgi-associated vesicle;GO:0005769//early endosome;GO:0090498//extrinsic component of Golgi membrane;GO:0098547//lumenal side of Golgi membrane","GO:0003677//DNA binding;GO:0001965//G-protein alpha-subunit binding;GO:0005509//calcium ion binding","GO:0043687//post-translational protein modification;GO:0044267//cellular protein metabolic process;GO:0072718//response to cisplatin;GO:1903533//regulation of protein targeting","K20371//nucleobindin","NP_006175.2//nucleobindin-1 precursor [Homo sapiens]",5]
[3959,2277,74.42,132.95,0.837121481619257,{"v":3.86725031724138E-104,"d":"3.87E-104"},"*",{"v":2.10624e-106,"d":"2.11E-106"},"LGALS3BP","GO:0016020//membrane;GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0072562//blood microparticle;GO:0031089//platelet dense granule lumen;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix","GO:0005044//scavenger receptor activity","GO:0002576//platelet degranulation;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0006968//cellular defense response","K17300//galectin-3-binding protein","NP_005558.1//galectin-3-binding protein precursor [Homo sapiens]","3//A2MP1"]
[54739,3487,0.28,0.5,0.836501267717121,0.220278323527385,"*",0.1200954,"XAF1","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005739//mitochondrion","GO:0008270//zinc ion binding","GO:0035456//response to interferon-beta;GO:0060337//type I interferon signaling pathway;GO:0034097//response to cytokine;GO:0031333//negative regulation of protein complex assembly;GO:0006915//apoptotic process","K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K15696//RING finger protein 113B;K01064//wingless-type MMTV integration site family, member 9","NP_001340069.1//XIAP-associated factor 1 isoform 7 [Homo sapiens];NP_001340068.1//XIAP-associated factor 1 isoform 6 [Homo sapiens];XP_005256765.1//PREDICTED: XIAP-associated factor 1 isoform X8 [Homo sapiens];XP_004058479.1//PREDICTED: XIAP-associated factor 1 isoform X5 [Gorilla gorilla gorilla];NP_001340067.1//XIAP-associated factor 1 isoform 5 [Homo sapiens];XP_005256763.1//PREDICTED: XIAP-associated factor 1 isoform X4 [Homo sapiens];XP_009249479.1//PREDICTED: XIAP-associated factor 1 isoform X2 [Pongo abelii];XP_009249478.1//PREDICTED: XIAP-associated factor 1 isoform X1 [Pongo abelii]","4;1//3;3//A2MP1"]
[81027,3496,0.23,0.41,0.833990048561071,0.240079540408437,"*",0.1346784,"TUBB1","GO:0070062//extracellular exosome;GO:0005874//microtubule;GO:0005737//cytoplasm","GO:0005200//structural constituent of cytoskeleton;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0051225//spindle assembly","K07375//tubulin beta","XP_004062495.1//PREDICTED: tubulin beta-1 chain isoform X1 [Gorilla gorilla gorilla]","3//A2MP1"]
[9314,2912,5.88,10.47,0.832373382094444,{"v":5.42771723925593e-11,"d":"5.43E-11"},"*",{"v":5.29724e-12,"d":"5.30E-12"},"KLF4","GO:0005654//nucleoplasm;GO:0044798//nuclear transcription factor complex;GO:0005719//nuclear euchromatin;GO:0000790//nuclear chromatin;GO:0005737//cytoplasm","GO:0001010//transcription factor activity, sequence-specific DNA binding transcription factor recruiting;GO:0042826//histone deacetylase binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0003676//nucleic acid binding;GO:0001190//transcriptional activator activity, RNA polymerase II transcription factor binding;GO:1990841//promoter-specific chromatin binding;GO:0000987//proximal promoter sequence-specific DNA binding;GO:0008013//beta-catenin binding;GO:0001047//core promoter binding","GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0090051//negative regulation of cell migration involved in sprouting angiogenesis;GO:0071409//cellular response to cycloheximide;GO:0032270//positive regulation of cellular protein metabolic process;GO:0051973//positive regulation of telomerase activity;GO:0071499//cellular response to laminar fluid shear stress;GO:0048730//epidermis morphogenesis;GO:1904998//negative regulation of leukocyte adhesion to arterial endothelial cell;GO:0071363//cellular response to growth factor stimulus;GO:0046985//positive regulation of hemoglobin biosynthetic process;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0008285//negative regulation of cell proliferation;GO:0070301//cellular response to hydrogen peroxide;GO:0060761//negative regulation of response to cytokine stimulus;GO:0009913//epidermal cell differentiation;GO:0032526//response to retinoic acid;GO:2000342//negative regulation of chemokine (C-X-C motif) ligand 2 production;GO:1904798//positive regulation of core promoter binding;GO:1990830//cellular response to leukemia inhibitory factor;GO:0060070//canonical Wnt signaling pathway;GO:0034115//negative regulation of heterotypic cell-cell adhesion;GO:0019827//stem cell population maintenance;GO:0031077//post-embryonic camera-type eye development;GO:0045444//fat cell differentiation;GO:0048679//regulation of axon regeneration;GO:0035166//post-embryonic hemopoiesis;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0045415//negative regulation of interleukin-8 biosynthetic process","K17846//krueppel-like factor 4","NP_004226.3//Krueppel-like factor 4 isoform 2 [Homo sapiens];NP_001300981.1//Krueppel-like factor 4 isoform 1 [Homo sapiens]","1//3;5"]
[9636,685,3.32,5.91,0.831974888830608,0.0370638565302984,"*",0.01508634,"ISG15","GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005576//extracellular region","GO:0031386//protein tag","GO:0032649//regulation of interferon-gamma production;GO:0031397//negative regulation of protein ubiquitination;GO:0060337//type I interferon signaling pathway;GO:0051607//defense response to virus;GO:0019941//modification-dependent protein catabolic process;GO:0042742//defense response to bacterium;GO:0016032//viral process;GO:0019985//translesion synthesis;GO:0034340//response to type I interferon;GO:0030501//positive regulation of bone mineralization;GO:0032020//ISG15-protein conjugation;GO:0045071//negative regulation of viral genome replication;GO:0045648//positive regulation of erythrocyte differentiation;GO:0032480//negative regulation of type I interferon production","K12159//ubiquitin cross-reactive protein","NP_005092.1//ubiquitin-like protein ISG15 [Homo sapiens]","3//A2MP1"]
[7101,2631,0.09,0.16,0.830074998557688,0.628607217797138,"*",0.505908,"NR2E1","GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0003707//steroid hormone receptor activity;GO:0042826//histone deacetylase binding;GO:0008270//zinc ion binding;GO:0043565//sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0060041//retina development in camera-type eye;GO:0007399//nervous system development;GO:0048712//negative regulation of astrocyte differentiation;GO:0060164//regulation of timing of neuron differentiation;GO:0007601//visual perception;GO:0035019//somatic stem cell population maintenance;GO:0002118//aggressive behavior;GO:0021772//olfactory bulb development;GO:2000648//positive regulation of stem cell proliferation;GO:0060291//long-term synaptic potentiation;GO:0021764//amygdala development;GO:0021819//layer formation in cerebral cortex;GO:0045766//positive regulation of angiogenesis;GO:0048814//regulation of dendrite morphogenesis;GO:0090049//regulation of cell migration involved in sprouting angiogenesis;GO:0045165//cell fate commitment;GO:0035176//social behavior;GO:0021960//anterior commissure morphogenesis;GO:0021895//cerebral cortex neuron differentiation;GO:0006351//transcription, DNA-templated;GO:0021542//dentate gyrus development;GO:0043066//negative regulation of apoptotic process;GO:2000178//negative regulation of neural precursor cell proliferation;GO:0001662//behavioral fear response;GO:2000179//positive regulation of neural precursor cell proliferation;GO:0045665//negative regulation of neuron differentiation;GO:0021872//forebrain generation of neurons;GO:0030198//extracellular matrix organization;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0045787//positive regulation of cell cycle","K08545//nuclear receptor subfamily 2 group E member 1","NP_003260.1//nuclear receptor subfamily 2 group E member 1 isoform b [Homo sapiens];XP_012361509.1//PREDICTED: nuclear receptor subfamily 2 group E member 1 isoform X1 [Nomascus leucogenys]","4;1//3"]
[146456,940,0.35,0.62,0.824913293441909,0.539872505606167,"*",0.385826,"TMED6","GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","NA","GO:0006810//transport","K20351//p24 family protein gamma-5","NP_653277.2//transmembrane emp24 domain-containing protein 6 precursor [Homo sapiens]","3//A2MP1"]
[124044,2388,5.39,9.54,0.823703993253006,{"v":2.3864265621162E-8,"d":"2.39E-08"},"*",{"v":3.16268e-09,"d":"3.16E-09"},"SPATA2L","NA","NA","NA","K17595//spermatogenesis-associated protein 2","NP_689552.2//spermatogenesis-associated protein 2-like protein [Homo sapiens]","3//A2MP1"]
[81693,1574,0.26,0.46,0.823122237915921,0.447388326393427,"*",0.299986,"AMN","GO:0070062//extracellular exosome;GO:0010008//endosome membrane;GO:0005615//extracellular space;GO:0016324//apical plasma membrane;GO:0031526//brush border membrane;GO:0030139//endocytic vesicle;GO:0005905//clathrin-coated pit;GO:0043234//protein complex;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005102//receptor binding","GO:0015889//cobalamin transport;GO:0043001//Golgi to plasma membrane protein transport;GO:0006898//receptor-mediated endocytosis;GO:0007275//multicellular organism development;GO:0007588//excretion;GO:0034384//high-density lipoprotein particle clearance;GO:0009235//cobalamin metabolic process","K18259//protein amnionless","NP_112205.2//protein amnionless precursor [Homo sapiens]","3//A2MP1"]
[139212,1678,0.13,0.23,0.823122237915921,0.609092046275967,"*",0.451538,"PIH1D3","GO:0005737//cytoplasm","GO:0051087//chaperone binding","GO:0003341//cilium movement;GO:0030317//flagellated sperm motility;GO:0070286//axonemal dynein complex assembly","K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K02927//large subunit ribosomal protein L40e;K17985//activating molecule in BECN1-regulated autophagy protein 1;K01064//wingless-type MMTV integration site family, member 9;K20164//DENN domain-containing protein 5","NP_775765.1//protein PIH1D3 [Homo sapiens]","1//3"]
[8320,3118,0.39,0.69,0.823122237915921,0.168756994237288,"*",0.0872626,"EOMES","GO:0005634//nucleus","GO:0003677//DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0043565//sequence-specific DNA binding;GO:0001191//transcriptional repressor activity, RNA polymerase II transcription factor binding;GO:0003700//DNA binding transcription factor activity;GO:0001102//RNA polymerase II activating transcription factor binding","GO:0060809//mesodermal to mesenchymal transition involved in gastrulation;GO:0001714//endodermal cell fate specification;GO:0001829//trophectodermal cell differentiation;GO:0001706//endoderm formation;GO:0021772//olfactory bulb development;GO:0007420//brain development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0001707//mesoderm formation;GO:0045597//positive regulation of cell differentiation;GO:0021796//cerebral cortex regionalization;GO:0021895//cerebral cortex neuron differentiation;GO:0006351//transcription, DNA-templated;GO:0045664//regulation of neuron differentiation;GO:0002302//CD8-positive, alpha-beta T cell differentiation involved in immune response;GO:0032609//interferon-gamma production;GO:0002250//adaptive immune response;GO:0035914//skeletal muscle cell differentiation;GO:0019827//stem cell population maintenance;GO:0060706//cell differentiation involved in embryonic placenta development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0010002//cardioblast differentiation","K10173//eomesodermin protein","BAH13105.1//unnamed protein product [Homo sapiens];NP_001265111.1//eomesodermin homolog isoform 1 [Homo sapiens];NP_005433.2//eomesodermin homolog isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[8338,437,1.6,2.83,0.82273014794452,0.236918250592709,"*",0.1326232,"HIST2H2AC","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0000786//nucleosome","GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity","GO:0006342//chromatin silencing","K11251//histone H2A","NP_003508.1//histone H2A type 2-C [Homo sapiens]","2//1"]
[54507,4145,1.25,2.21,0.822118274729345,0.000471035662891278,"*",0.0001234058,"ADAMTSL4","GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0005614//interstitial matrix","GO:0002020//protease binding;GO:0008233//peptidase activity","GO:0043065//positive regulation of apoptotic process;GO:0002064//epithelial cell development;GO:0030198//extracellular matrix organization;GO:0036066//protein O-linked fucosylation;GO:0006915//apoptotic process","K08630//a disintegrin and metalloproteinase with thrombospondin motifs 16 [EC:3.4.24.-];K08625//a disintegrin and metalloproteinase with thrombospondin motifs 10 [EC:3.4.24.-];K09609//a disintegrin and metalloproteinase with thrombospondin motifs 20 [EC:3.4.24.-];K08632//a disintegrin and metalloproteinase with thrombospondin motifs 18 [EC:3.4.24.-]","XP_011507946.1//PREDICTED: ADAMTS-like protein 4 isoform X1 [Homo sapiens];XP_011507947.1//PREDICTED: ADAMTS-like protein 4 isoform X2 [Homo sapiens];NP_001275536.1//ADAMTS-like protein 4 isoform 3 precursor [Homo sapiens]","4;1//3;5"]
[7052,5127,62.99,111.35,0.821906841789814,{"v":1.88272226333333E-181,"d":"1.88E-181"},"*",{"v":4.24302e-184,"d":"4.24E-184"},"TGM2","GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0031226//intrinsic component of plasma membrane;GO:0005783//endoplasmic reticulum;GO:0005925//focal adhesion;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005886//plasma membrane","GO:0046872//metal ion binding;GO:0019904//protein domain specific binding;GO:0005525//GTP binding;GO:0003810//protein-glutamine gamma-glutamyltransferase activity","GO:0060445//branching involved in salivary gland morphogenesis;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway;GO:0045785//positive regulation of cell adhesion;GO:0051260//protein homooligomerization;GO:0050729//positive regulation of inflammatory response;GO:0032471//negative regulation of endoplasmic reticulum calcium ion concentration;GO:0043277//apoptotic cell clearance;GO:0051561//positive regulation of mitochondrial calcium ion concentration;GO:0018149//peptide cross-linking;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0001974//blood vessel remodeling;GO:0018153//isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine;GO:0043065//positive regulation of apoptotic process;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0060662//salivary gland cavitation","K05625//transglutaminase 2 [EC:2.3.2.13]","NP_945189.1//protein-glutamine gamma-glutamyltransferase 2 isoform b [Homo sapiens];NP_001310246.1//protein-glutamine gamma-glutamyltransferase 2 isoform c [Homo sapiens];NP_004604.2//protein-glutamine gamma-glutamyltransferase 2 isoform a [Homo sapiens];NP_001310247.1//protein-glutamine gamma-glutamyltransferase 2 isoform d [Homo sapiens]","1//3;3//A2MP1;2//1"]
[10068,1313,8.46,14.95,0.821415915965518,{"v":3.90783936713996e-05,"d":"3.91E-05"},"*",{"v":8.44244e-06,"d":"8.44E-06"},"IL18BP","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005576//extracellular region","GO:0048019//receptor antagonist activity;GO:0042007//interleukin-18 binding","GO:0042088//T-helper 1 type immune response;GO:0032496//response to lipopolysaccharide;GO:0071356//cellular response to tumor necrosis factor;GO:0070301//cellular response to hydrogen peroxide","K15698//RING finger protein 121","XP_009245053.1//PREDICTED: interleukin-18-binding protein isoform X1 [Pongo abelii];NP_001138527.1//interleukin-18-binding protein isoform b precursor [Homo sapiens];XP_009245054.1//PREDICTED: interleukin-18-binding protein isoform X2 [Pongo abelii];NP_766632.2//interleukin-18-binding protein isoform d precursor [Homo sapiens]","1//3;3//A2MP1;2//1"]
[2073,4091,1.57,2.77,0.819121417157562,1.18408988948498E-4,"*",{"v":2.76342E-5,"d":"2.76E-05"},"ERCC5","GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0004520//endodeoxyribonuclease activity;GO:0003697//single-stranded DNA binding;GO:0046872//metal ion binding;GO:0000405//bubble DNA binding;GO:0047485//protein N-terminus binding;GO:0042803//protein homodimerization activity;GO:0003690//double-stranded DNA binding","GO:0009650//UV protection;GO:0009411//response to UV;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0006296//nucleotide-excision repair, DNA incision, 5'-to lesion;GO:0006295//nucleotide-excision repair, DNA incision, 3'-to lesion;GO:0043066//negative regulation of apoptotic process;GO:0006294//nucleotide-excision repair, preincision complex assembly;GO:0010225//response to UV-C;GO:0033683//nucleotide-excision repair, DNA incision;GO:0006293//nucleotide-excision repair, preincision complex stabilization","K10846//DNA excision repair protein ERCC-5","NP_000114.2//DNA repair protein complementing XP-G cells [Homo sapiens]","3//A2MP1"]
[221749,2211,7.68,13.55,0.819114635520078,{"v":1.4333982945679e-10,"d":"1.43E-10"},"*",{"v":1.453678E-11,"d":"1.45E-11"},"PXDC1","NA","GO:0035091//phosphatidylinositol binding","NA","K13172//serine/arginine repetitive matrix protein 2;K13171//serine/arginine repetitive matrix protein 1","NP_899229.2//PX domain-containing protein 1 [Homo sapiens]","3//A2MP1"]
[79446,1380,5.74,10.12,0.818086648018622,{"v":3.84864851306795E-7,"d":"3.85E-07"},"*",{"v":5.99198e-08,"d":"5.99E-08"},"WDR25","NA","NA","NA","K12816//pre-mRNA-processing factor 17","NP_001337879.1//WD repeat-containing protein 25 isoform c [Homo sapiens];NP_001337878.1//WD repeat-containing protein 25 isoform b [Homo sapiens];NP_001154948.1//WD repeat-containing protein 25 isoform a [Homo sapiens]","1//3;2//1;5"]
[4815,986,0.59,1.04,0.817796668779251,0.402927189189189,"*",0.26132,"NINJ2","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane","NA","GO:0007399//nervous system development;GO:0007155//cell adhesion;GO:0042246//tissue regeneration;GO:0007158//neuron cell-cell adhesion","NA","NP_057617.2//ninjurin-2 isoform 1 [Homo sapiens];NP_001281274.1//ninjurin-2 isoform 2 [Homo sapiens];AAH57766.2//NINJ2 protein, partial [Homo sapiens]","1//3;5"]
[56892,1841,17.13,30.19,0.817545605429626,{"v":8.8786846921241e-19,"d":"8.88E-19"},"*",{"v":4.65778e-20,"d":"4.66E-20"},"TCIM","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016607//nuclear speck;GO:0005622//intracellular;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0005112//Notch binding","GO:0010739//positive regulation of protein kinase A signaling;GO:0002264//endothelial cell activation involved in immune response;GO:0043066//negative regulation of apoptotic process;GO:0034605//cellular response to heat;GO:1902806//regulation of cell cycle G1/S phase transition;GO:0042346//positive regulation of NF-kappaB import into nucleus;GO:0006915//apoptotic process;GO:0043620//regulation of DNA-templated transcription in response to stress;GO:1900020//positive regulation of protein kinase C activity;GO:0045746//negative regulation of Notch signaling pathway;GO:1903706//regulation of hemopoiesis","NA","XP_003432158.2//protein C8orf4 homolog [Canis lupus familiaris]",4]
[90288,2169,0.63,1.11,0.81713594285019,0.121272769147005,"*",0.0585638,"EFCAB12","NA","GO:0005509//calcium ion binding","NA","NA","NP_997190.1//EF-hand calcium-binding domain-containing protein 12 [Homo sapiens]","2//1"]
[57091,1892,0.25,0.44,0.815575428862573,0.344501586442079,"*",0.208698,"CASS4","GO:0005856//cytoskeleton;GO:0005925//focal adhesion;GO:0005737//cytoplasm","NA","GO:0007155//cell adhesion","K16832//enhancer of filamentation 1","NP_001157586.1//cas scaffolding protein family member 4 isoform b [Homo sapiens];NP_065089.2//cas scaffolding protein family member 4 isoform a [Homo sapiens];NP_001157587.1//cas scaffolding protein family member 4 isoform c [Homo sapiens]","1//3;3//A2MP1"]
[7128,4721,2.41,4.24,0.815031118333237,{"v":1.6691076097973e-07,"d":"1.67E-07"},"*",{"v":2.4743e-08,"d":"2.47E-08"},"TNFAIP3","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0005764//lysosome;GO:0005737//cytoplasm","GO:0070530//K63-linked polyubiquitin modification-dependent protein binding;GO:0003677//DNA binding;GO:0042802//identical protein binding;GO:0019900//kinase binding","GO:0001922//B-1 B cell homeostasis;GO:0071222//cellular response to lipopolysaccharide;GO:0070301//cellular response to hydrogen peroxide;GO:0006915//apoptotic process","K11859//tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12]","XP_012361594.1//PREDICTED: tumor necrosis factor alpha-induced protein 3 isoform X1 [Nomascus leucogenys];XP_004087703.1//PREDICTED: tumor necrosis factor alpha-induced protein 3 isoform X2 [Nomascus leucogenys];XP_003255830.1//PREDICTED: tumor necrosis factor alpha-induced protein 3 isoform X3 [Nomascus leucogenys]","1//3;3//A2MP1"]
[144406,3578,1.74,3.06,0.814444346843923,2.85650971870324E-4,"*",{"v":7.17078e-05,"d":"7.17E-05"},"WDR66","GO:0031514//motile cilium;GO:0005737//cytoplasm;GO:0005930//axoneme","NA","GO:0003341//cilium movement","K19538//retinitis pigmentosa 1;K19607//X-linked retinitis pigmentosa GTPase regulator","NP_001171474.1//cilia- and flagella-associated protein 251 isoform 2 [Homo sapiens];NP_653269.3//cilia- and flagella-associated protein 251 isoform 1 [Homo sapiens]","1//3;5"]
[3620,1944,4.91,8.63,0.813637534864262,{"v":2.82129822362869e-06,"d":"2.82E-06"},"*",{"v":5.02302e-07,"d":"5.02E-07"},"IDO1","GO:0032421//stereocilium bundle;GO:0005829//cytosol;GO:0030485//smooth muscle contractile fiber","GO:0009055//electron transfer activity;GO:0046872//metal ion binding;GO:0020037//heme binding;GO:0033754//indoleamine 2,3-dioxygenase activity;GO:0004833//tryptophan 2,3-dioxygenase activity","GO:0034276//kynurenic acid biosynthetic process;GO:0032693//negative regulation of interleukin-10 production;GO:0032496//response to lipopolysaccharide;GO:0042130//negative regulation of T cell proliferation;GO:0032735//positive regulation of interleukin-12 production;GO:0002376//immune system process;GO:0033555//multicellular organismal response to stress;GO:0036269//swimming behavior;GO:0070233//negative regulation of T cell apoptotic process;GO:0007565//female pregnancy;GO:0070234//positive regulation of T cell apoptotic process;GO:0002678//positive regulation of chronic inflammatory response;GO:0006569//tryptophan catabolic process;GO:0002534//cytokine production involved in inflammatory response;GO:0002830//positive regulation of type 2 immune response;GO:0002666//positive regulation of T cell tolerance induction;GO:0019441//tryptophan catabolic process to kynurenine","K00463//indoleamine 2,3-dioxygenase [EC:1.13.11.52]","NP_002155.1//indoleamine 2,3-dioxygenase 1 [Homo sapiens]",5]
[129530,1015,0.97,1.7,0.809478093950574,0.220303619614148,"*",0.1200954,"LYG1","GO:0005576//extracellular region","GO:0003796//lysozyme activity","GO:0016998//cell wall macromolecule catabolic process;GO:0009253//peptidoglycan catabolic process","K01446//peptidoglycan recognition protein","NP_777558.1//lysozyme g-like protein 1 precursor [Homo sapiens]","2//1"]
[284207,1633,3.81,6.67,0.807895763691263,0.000243751347480375,"*",{"v":6.02588E-5,"d":"6.03E-05"},"METRNL","GO:0070062//extracellular exosome;GO:0005615//extracellular space","GO:0005179//hormone activity","GO:0014850//response to muscle activity;GO:2000507//positive regulation of energy homeostasis;GO:0009409//response to cold;GO:0045444//fat cell differentiation;GO:0050873//brown fat cell differentiation;GO:0090336//positive regulation of brown fat cell differentiation;GO:0050728//negative regulation of inflammatory response","K00901//diacylglycerol kinase (ATP) [EC:2.7.1.107]","NP_001004431.1//meteorin-like protein precursor [Homo sapiens]","2//1"]
[7087,3005,0.32,0.56,0.807354922057604,0.220328921511428,"*",0.1200954,"ICAM5","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005178//integrin binding","GO:0007155//cell adhesion;GO:0030198//extracellular matrix organization;GO:0050776//regulation of immune response;GO:0006909//phagocytosis","K06769//intercellular adhesion molecule 5","NP_003250.3//intercellular adhesion molecule 5 precursor [Homo sapiens]","3//A2MP1"]
[1830,5561,0.32,0.56,0.807354922057604,0.0670097807095028,"*",0.0294442,"DSG3","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0001533//cornified envelope;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0030057//desmosome","GO:0005509//calcium ion binding","GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0031424//keratinization;GO:0070268//cornification","K07598//desmoglein 3","NP_001935.2//desmoglein-3 preproprotein [Homo sapiens]","2//1"]
[339766,5324,0.16,0.28,0.807354922057604,0.259472636130306,"*",0.1480914,"MROH2A","NA","NA","NA","K19719//collagen, type II, alpha;K06236//collagen, type I, alpha","XP_011509381.1//PREDICTED: maestro heat-like repeat-containing protein family member 2A isoform X5 [Homo sapiens]","1//3"]
[100507050,2820,0.08,0.14,0.807354922057604,0.629194518218623,"*",0.505908,"TPBGL","GO:0016021//integral component of membrane","NA","NA","K16628//collagen, type VII, alpha;K06236//collagen, type I, alpha","NP_001182457.1//trophoblast glycoprotein-like precursor [Homo sapiens]","1//3"]
[26249,6806,0.08,0.14,0.807354922057604,0.402810545208916,"*",0.26132,"KLHL3","GO:0005856//cytoskeleton;GO:0005829//cytosol;GO:0031463//Cul3-RING ubiquitin ligase complex","GO:0003779//actin binding;GO:0005198//structural molecule activity","GO:0070294//renal sodium ion absorption;GO:0070936//protein K48-linked ubiquitination;GO:0043687//post-translational protein modification;GO:0016567//protein ubiquitination;GO:0050801//ion homeostasis;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0072156//distal tubule morphogenesis","K10443//kelch-like protein 2/3","DAA27455.1//TPA: KIAA1129 protein-like [Bos taurus];XP_021520606.1//kelch-like protein 3 isoform X3 [Aotus nancymaae];XP_011714779.1//PREDICTED: kelch-like protein 3 isoform X3 [Macaca nemestrina]","1//3;2//1"]
[2155,2892,0.08,0.14,0.807354922057604,0.628656117619603,"*",0.505908,"F7","NA","NA","NA","K01320//coagulation factor VII [EC:3.4.21.21]","XP_009425587.1//PREDICTED: LOW QUALITY PROTEIN: coagulation factor VII [Pan troglodytes];XP_009247078.1//PREDICTED: coagulation factor VII isoform X2 [Pongo abelii]","1//3;4;3//A2MP1"]
[283383,5405,0.04,0.07,0.807354922057604,0.628411694556765,"*",0.505908,"ADGRD1","GO:0005622//intracellular;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004930//G-protein coupled receptor activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0007166//cell surface receptor signaling pathway","K08465//G protein-coupled receptor 133","XP_016780139.1//PREDICTED: adhesion G-protein coupled receptor D1 isoform X1 [Pan troglodytes];NP_942122.2//adhesion G-protein coupled receptor D1 isoform 1 precursor [Homo sapiens]","1//3;4"]
[5630,1833,0.4,0.7,0.807354922057604,0.287590168627451,"*",0.1671098,"PRPH","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005882//intermediate filament;GO:0045098//type III intermediate filament","GO:0005198//structural molecule activity","NA","K07607//peripherin","XP_012296710.1//peripherin isoform X2 [Aotus nancymaae]","3//A2MP1"]
[4005,1605,0.2,0.35,0.807354922057604,0.540109063535185,"*",0.385826,"LMO2","GO:0005654//nucleoplasm;GO:0005667//transcription factor complex","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0070888//E-box binding;GO:0001190//transcriptional activator activity, RNA polymerase II transcription factor binding;GO:0046872//metal ion binding;GO:0043425//bHLH transcription factor binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0048037//cofactor binding;GO:0001102//RNA polymerase II activating transcription factor binding","GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007275//multicellular organism development;GO:1902036//regulation of hematopoietic stem cell differentiation;GO:0042789//mRNA transcription from RNA polymerase II promoter;GO:0097067//cellular response to thyroid hormone stimulus","K15612//rhombotin-2","XP_006864973.1//PREDICTED: Wilms tumor protein 1-interacting protein-like [Chrysochloris asiatica];XP_011722342.1//PREDICTED: rhombotin-2 isoform X1 [Macaca nemestrina];XP_008000602.1//PREDICTED: rhombotin-2 isoform X1 [Chlorocebus sabaeus]","1//3;3//A2MP1"]
[3075,2608,4.92,8.58,0.802319332160306,{"v":1.45126065807327e-11,"d":"1.45E-11"},"*",{"v":1.33915E-12,"d":"1.34E-12"},"CFH","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0072562//blood microparticle;GO:0005576//extracellular region","GO:0043395//heparan sulfate proteoglycan binding;GO:0008201//heparin binding","GO:0030449//regulation of complement activation;GO:0006956//complement activation;GO:0006957//complement activation, alternative pathway;GO:0016032//viral process","K04004//complement factor H","NP_000177.2//complement factor H isoform a precursor [Homo sapiens];NP_001014975.1//complement factor H isoform b precursor [Homo sapiens]","3//A2MP1;2//1"]
[716,2775,16.76,29.22,0.801934029104147,{"v":2.80948045393258e-23,"d":"2.81E-23"},"*",{"v":1.095722e-24,"d":"1.10E-24"},"C1S","GO:0070062//extracellular exosome;GO:0072562//blood microparticle;GO:0005576//extracellular region","GO:0004252//serine-type endopeptidase activity;GO:0042802//identical protein binding;GO:0005509//calcium ion binding","GO:0006958//complement activation, classical pathway;GO:0030449//regulation of complement activation;GO:0006956//complement activation;GO:0001867//complement activation, lectin pathway","K01331//complement component 1, s subcomponent [EC:3.4.21.42]","NP_001725.1//complement C1s subcomponent isoform 1 preproprotein [Homo sapiens]","1//3;4;3//A2MP1"]
[53842,2708,0.35,0.61,0.80145432061792,0.279111298709188,"*",0.1610822,"CLDN22","GO:0016021//integral component of membrane;GO:0005923//bicellular tight junction;GO:0005886//plasma membrane","GO:0042802//identical protein binding;GO:0005198//structural molecule activity","GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules","K06087//claudin","NP_001104789.1//claudin-22 [Homo sapiens]","1//3"]
[135112,4410,17.48,30.45,0.800737043293096,{"v":1.2211217257732E-32,"d":"1.22E-32"},"*",{"v":2.96604E-34,"d":"2.97E-34"},"NCOA7","GO:0005634//nucleus;GO:0005622//intracellular","GO:0035257//nuclear hormone receptor binding;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity","GO:1902083//negative regulation of peptidyl-cysteine S-nitrosylation;GO:1903204//negative regulation of oxidative stress-induced neuron death;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated","K12581//CCR4-NOT transcription complex subunit 7/8;K21841//TBC1 domain family member 24;K20634//Rho GTPase-activating protein 9;K12587//exosome complex component MTR3","NP_861447.3//nuclear receptor coactivator 7 isoform 1 [Homo sapiens];NP_001186551.1//nuclear receptor coactivator 7 isoform 4 [Homo sapiens];NP_001116314.1//nuclear receptor coactivator 7 isoform 2 [Homo sapiens]","1//3;4;2//1"]
[493861,1486,4.63,8.06,0.799767645267731,0.000136133977777778,"*",{"v":3.2214E-5,"d":"3.22E-05"},"EID3","NA","NA","NA","K22182//thioredoxin reductase (NADPH) [EC:1.8.1.9]","XP_008002676.1//PREDICTED: thioredoxin reductase 1, cytoplasmic isoform X8 [Chlorocebus sabaeus]","2//1"]
[192134,2560,0.23,0.4,0.798366138830349,0.402732820067535,"*",0.26132,"B3GNT6","GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0008499//UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity;GO:0047223//beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity;GO:0008378//galactosyltransferase activity;GO:0047224//acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity","GO:0006486//protein glycosylation;GO:0016269//O-glycan processing, core 3;GO:0009101//glycoprotein biosynthetic process;GO:0016266//O-glycan processing","K00739//acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase [EC:2.4.1.147]","NP_619651.3//acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase [Homo sapiens]",4]
[692312,3263,8.03,13.96,0.797827048692338,{"v":3.78191658483755e-15,"d":"3.78E-15"},"*",{"v":2.62324e-16,"d":"2.62E-16"},"PPAN-P2RY11","GO:0005634//nucleus;GO:0005730//nucleolus;GO:0016021//integral component of membrane;GO:0030687//preribosome, large subunit precursor","GO:0045028//G-protein coupled purinergic nucleotide receptor activity;GO:0003723//RNA binding;GO:0019843//rRNA binding","GO:0000027//ribosomal large subunit assembly","K14859//ribosome biogenesis protein SSF1/2","NP_001035754.1//PPAN-P2RY11 protein isoform 1 [Homo sapiens];NP_001185619.1//PPAN-P2RY11 protein isoform 2 [Homo sapiens]","1//3;2//1"]
[10326,1971,0.34,0.59,0.795180208111502,0.236838792263835,"*",0.1326232,"SIRPB1","GO:0070062//extracellular exosome;GO:0030667//secretory granule membrane;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","NA","GO:0007165//signal transduction;GO:0043312//neutrophil degranulation;GO:0007166//cell surface receptor signaling pathway;GO:0045087//innate immune response","K06551//signal-regulatory protein alpha/beta1/gamma","NP_006056.2//signal-regulatory protein beta-1 isoform 1 precursor [Homo sapiens];NP_001317568.1//signal-regulatory protein beta-1 isoform 4 precursor [Homo sapiens];NP_001077379.1//signal-regulatory protein beta-1 isoform 2 precursor [Homo sapiens];NP_001129316.1//signal-regulatory protein beta-1 isoform 3 precursor [Homo sapiens]","4;1//3;3//A2MP1"]
[255783,849,16.25,28.19,0.794743759767243,{"v":5.54174592466368E-8,"d":"5.54E-08"},"*",{"v":7.73638e-09,"d":"7.74E-09"},"INAFM1","GO:0016021//integral component of membrane","NA","NA","NA","EAW57469.1//hCG1820496 [Homo sapiens]",5]
[57732,3293,0.88,1.52,0.788495894806288,0.0244843371846079,"*",0.00944028,"ZFYVE28","GO:0031901//early endosome membrane;GO:0005829//cytosol","GO:0046872//metal ion binding;GO:0032266//phosphatidylinositol-3-phosphate binding","GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0007175//negative regulation of epidermal growth factor-activated receptor activity","K06236//collagen, type I, alpha;K18082//myotubularin-related protein 3/4 [EC:3.1.3.48 3.1.3.64 3.1.3.95];K17603//zinc finger FYVE domain-containing protein 1;K06831//galectin-3","NP_001166129.1//lateral signaling target protein 2 homolog isoform 5 [Homo sapiens];NP_001166127.1//lateral signaling target protein 2 homolog isoform 3 [Homo sapiens];NP_001166128.1//lateral signaling target protein 2 homolog isoform 4 [Homo sapiens];NP_066023.2//lateral signaling target protein 2 homolog isoform 2 [Homo sapiens];XP_017731740.1//PREDICTED: lateral signaling target protein 2 homolog isoform X7 [Rhinopithecus bieti]","1//3;2//1"]
[84527,2949,0.77,1.33,0.788495894806288,0.0896911001087548,"*",0.0413026,"ZNF559","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","XP_017171189.1//PREDICTED: zinc finger protein 431-like, partial [Mus musculus];XP_017169913.1//PREDICTED: predicted gene 14295 isoform X1 [Mus musculus]","1//3;2//1"]
[23217,4757,0.33,0.57,0.788495894806288,0.251487957624682,"*",0.1423692,"ZFR2","NA","GO:0008270//zinc ion binding;GO:0003676//nucleic acid binding","NA","K08888//megakaryocyte-associated tyrosine kinase [EC:2.7.10.2];K17602//YLP motif-containing protein 1;K13203//zinc finger RNA-binding protein;K12968//double-stranded RNA-specific adenosine deaminase [EC:3.5.4.37]","NP_001139112.1//zinc finger RNA-binding protein 2 isoform 2 [Homo sapiens];NP_055989.1//zinc finger RNA-binding protein 2 isoform 1 [Homo sapiens]","1//3"]
[92960,1061,1.39,2.4,0.787949522885011,0.130073534878981,"*",0.0639212,"PEX11G","GO:0005779//integral component of peroxisomal membrane;GO:0031231//intrinsic component of peroxisomal membrane;GO:0043234//protein complex;GO:0005777//peroxisome","NA","GO:0044375//regulation of peroxisome size;GO:0016559//peroxisome fission","K13353//peroxin-11C","NP_542393.1//peroxisomal membrane protein 11C isoform 1 [Homo sapiens];NP_001257468.1//peroxisomal membrane protein 11C isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[1465,1932,207.54,357.76,0.785602673749106,{"v":3.03948119096774e-212,"d":"3.04E-212"},"*",{"v":5.89858e-215,"d":"5.90E-215"},"CSRP1","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005925//focal adhesion","GO:0046872//metal ion binding;GO:0003723//RNA binding;GO:0008270//zinc ion binding","GO:0070527//platelet aggregation","K09377//cysteine and glycine-rich protein","XP_003767613.2//PREDICTED: cysteine and glycine-rich protein 1 [Sarcophilus harrisii];XP_011845940.1//PREDICTED: cysteine and glycine-rich protein 1 isoform X1 [Mandrillus leucophaeus];EDL39573.1//cysteine and glycine-rich protein 1, isoform CRA_a, partial [Mus musculus]","1//3;2//1"]
[641371,1603,2.46,4.24,0.785405949223959,0.00504564959643687,"*",1.631134E-3,"ACOT1","NA","NA","NA","K01068//acyl-coenzyme A thioesterase 1/2/4 [EC:3.1.2.2]","XP_012596914.2//acyl-coenzyme A thioesterase 1 isoform X2 [Microcebus murinus]","1//3"]
[15,1105,0.47,0.81,0.785261151206987,0.315494397938144,"*",0.1877482,"AANAT","GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm","GO:0004059//aralkylamine N-acetyltransferase activity;GO:0071889//14-3-3 protein binding;GO:0004060//arylamine N-acetyltransferase activity","GO:0007623//circadian rhythm;GO:0032868//response to insulin;GO:0046219//indolalkylamine biosynthetic process;GO:0034695//response to prostaglandin E;GO:0009416//response to light stimulus;GO:0034097//response to cytokine;GO:0010043//response to zinc ion;GO:0046688//response to copper ion;GO:0071320//cellular response to cAMP;GO:0030187//melatonin biosynthetic process;GO:0051592//response to calcium ion;GO:0006474//N-terminal protein amino acid acetylation;GO:0009648//photoperiodism;GO:0051412//response to corticosterone","K00669//arylalkylamine N-acetyltransferase [EC:2.3.1.87]","XP_016879748.1//PREDICTED: serotonin N-acetyltransferase isoform X1 [Homo sapiens];NP_001160051.1//serotonin N-acetyltransferase isoform 1 [Homo sapiens]","1//3;2//1"]
[151651,2857,0.36,0.62,0.784271308944563,0.330740895694777,"*",0.1986226,"EFHB","NA","GO:0005509//calcium ion binding","NA","K02183//calmodulin;K10869//RAD51-like protein 1;K04460//serine/threonine-protein phosphatase 5 [EC:3.1.3.16]","NP_001317617.1//EF-hand domain-containing family member B isoform 2 [Homo sapiens];NP_653316.3//EF-hand domain-containing family member B isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[51365,1801,0.18,0.31,0.784271308944563,0.539919800613228,"*",0.385826,"PLA1A","GO:0070062//extracellular exosome;GO:0005576//extracellular region;GO:0002080//acrosomal membrane","GO:0052739//phosphatidylserine 1-acylhydrolase activity;GO:0052689//carboxylic ester hydrolase activity;GO:0008970//phosphatidylcholine 1-acylhydrolase activity","GO:0006658//phosphatidylserine metabolic process;GO:0016042//lipid catabolic process;GO:0036150//phosphatidylserine acyl-chain remodeling;GO:0006629//lipid metabolic process","K13618//phospholipase A1 member A [EC:3.1.1.-]","NP_001193889.1//phospholipase A1 member A isoform 2 precursor [Homo sapiens];NP_001280154.1//phospholipase A1 member A isoform 4 [Homo sapiens];NP_056984.1//phospholipase A1 member A isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[23329,7659,0.25,0.43,0.782408564927373,0.0611081955376422,"*",0.0265756,"TBC1D30","GO:0012505//endomembrane system;GO:0005929//cilium;GO:0036064//ciliary basal body;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0017137//Rab GTPase binding;GO:0005096//GTPase activator activity","GO:0006886//intracellular protein transport;GO:0090630//activation of GTPase activity;GO:0031338//regulation of vesicle fusion;GO:0043547//positive regulation of GTPase activity;GO:1902018//negative regulation of cilium assembly","K20165//TBC1 domain family member 2A;K19953//TBC1 domain family member 6","NP_001317115.1//TBC1 domain family member 30 isoform 2 [Homo sapiens];NP_056094.1//TBC1 domain family member 30 isoform 1 [Homo sapiens];BAA76828.1//KIAA0984 protein, partial [Homo sapiens]","1//3"]
[285966,4867,1.07,1.84,0.782094969655866,0.00984390144023218,"*",0.00339736,"TCAF2","GO:0005886//plasma membrane","GO:0044325//ion channel binding","GO:0006810//transport;GO:0030335//positive regulation of cell migration;GO:0030336//negative regulation of cell migration;GO:0090314//positive regulation of protein targeting to membrane;GO:1901529//positive regulation of anion channel activity;GO:0010360//negative regulation of anion channel activity","K22069//LYR motif-containing protein 4;K12581//CCR4-NOT transcription complex subunit 7/8;K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K01587//phosphoribosylaminoimidazole carboxylase / phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:4.1.1.21 6.3.2.6];K15259//poly [ADP-ribose] polymerase 7/11/12/13 [EC:2.4.2.30]","EHH61538.1//hypothetical protein EGM_19442 [Macaca fascicularis];NP_001123498.2//TRPM8 channel-associated factor 2 isoform B [Homo sapiens]","1//3;2//1"]
[93349,2519,2.22,3.81,0.779231321143216,9.39609007874016E-4,"*",0.00026146,"SP140L","GO:0016604//nuclear body","GO:0046872//metal ion binding;GO:0003677//DNA binding","NA","K15413//nuclear autoantigen Sp-100","NP_612411.4//nuclear body protein SP140-like protein isoform 1 [Homo sapiens];NP_001339823.1//nuclear body protein SP140-like protein isoform 6 [Homo sapiens];NP_001339821.1//nuclear body protein SP140-like protein isoform 4 [Homo sapiens];NP_001295092.1//nuclear body protein SP140-like protein isoform 3 [Homo sapiens];NP_001339822.1//nuclear body protein SP140-like protein isoform 5 [Homo sapiens];NP_001295091.1//nuclear body protein SP140-like protein isoform 2 [Homo sapiens]","1//3;2//1;5"]
[654254,2341,0.07,0.12,0.777607578663552,0.782423613400957,"*",0.685686,"ZNF732","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_003310254.2//PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 732 [Pan troglodytes]","2//1"]
[1844,1708,0.14,0.24,0.777607578663552,0.629243509460407,"*",0.505908,"DUSP2","GO:0005634//nucleus;GO:0031965//nuclear membrane","GO:0008330//protein tyrosine/threonine phosphatase activity;GO:0017017//MAP kinase tyrosine/serine/threonine phosphatase activity;GO:0051019//mitogen-activated protein kinase binding;GO:0004725//protein tyrosine phosphatase activity","GO:0006470//protein dephosphorylation;GO:0001706//endoderm formation;GO:0000188//inactivation of MAPK activity","K04459//dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48]","XP_016804459.1//PREDICTED: dual specificity protein phosphatase 2 [Pan troglodytes]","3//A2MP1"]
[27334,3397,0.07,0.12,0.777607578663552,0.628900730894942,"*",0.505908,"P2RY10","NA","NA","NA","K04274//purinergic receptor P2Y, G protein-coupled, 10","NP_001311154.1//putative P2Y purinoceptor 10 isoform c [Homo sapiens];XP_004064490.1//PREDICTED: putative P2Y purinoceptor 10 isoform X1 [Gorilla gorilla gorilla];XP_002831884.1//PREDICTED: putative P2Y purinoceptor 10 isoform X2 [Pongo abelii]","1//3;3//A2MP1;2//1"]
[389602,4584,0.07,0.12,0.777607578663552,0.53982521888412,"*",0.385826,"LOC389602","NA","NA","NA","NA","EAL23914.1//hypothetical gene supported by AK124321 [Homo sapiens]","2//1"]
[919,1687,0.14,0.24,0.777607578663552,0.628802862745098,"*",0.505908,"CD247","GO:0042101//T cell receptor complex;GO:0042105//alpha-beta T cell receptor complex;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0042802//identical protein binding;GO:0004888//transmembrane signaling receptor activity;GO:1990782//protein tyrosine kinase binding;GO:0042803//protein homodimerization activity","GO:0051289//protein homotetramerization;GO:0050852//T cell receptor signaling pathway;GO:0050690//regulation of defense response to virus by virus;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0007166//cell surface receptor signaling pathway;GO:0031295//T cell costimulation;GO:0050776//regulation of immune response;GO:0070207//protein homotrimerization;GO:0002250//adaptive immune response","K06453//CD3Z antigen, zeta polypeptide","EAW90790.1//CD247 antigen, isoform CRA_a [Homo sapiens]","3//A2MP1;2//1"]
[64857,7642,24.84,42.56,0.776832977280708,{"v":6.52744721263158e-100,"d":"6.53E-100"},"*",{"v":3.88198e-102,"d":"3.88E-102"},"PLEKHG2","GO:0005829//cytosol","GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005089//Rho guanyl-nucleotide exchange factor activity","GO:0030833//regulation of actin filament polymerization;GO:0043065//positive regulation of apoptotic process;GO:0035023//regulation of Rho protein signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction","K20685//guanine nucleotide exchange factor MCF2;K16463//centrosomal protein CEP170;K05769//Rho guanine nucleotide exchange factor 4/29","NP_001338623.1//pleckstrin homology domain-containing family G member 2 isoform 3 [Homo sapiens];NP_001338622.1//pleckstrin homology domain-containing family G member 2 isoform 2 [Homo sapiens];NP_073746.2//pleckstrin homology domain-containing family G member 2 isoform 1 [Homo sapiens]","1//3;2//1"]
[4071,1712,276.87,474.29,0.776560710495204,{"v":1.70266105333333E-243,"d":"1.70E-243"},"*",{"v":2.23838E-246,"d":"2.24E-246"},"TM4SF1","GO:0005887//integral component of plasma membrane","NA","NA","K00681//gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13];K13624//ceruloplasmin [EC:1.16.3.1]","NP_055035.1//transmembrane 4 L6 family member 1 [Homo sapiens]","2//1"]
[7126,3822,27.05,46.32,0.776006659275059,{"v":3.80474056666667e-54,"d":"3.80E-54"},"*",{"v":4.85894e-56,"d":"4.86E-56"},"TNFAIP1","GO:0005768//endosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0031463//Cul3-RING ubiquitin ligase complex","GO:0019904//protein domain specific binding;GO:0017049//GTP-Rho binding;GO:0004842//ubiquitin-protein transferase activity","GO:0016477//cell migration;GO:0006260//DNA replication;GO:0016567//protein ubiquitination;GO:0051260//protein homooligomerization;GO:0045740//positive regulation of DNA replication;GO:0006915//apoptotic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0009790//embryo development;GO:0006955//immune response;GO:0035024//negative regulation of Rho protein signal transduction;GO:0043149//stress fiber assembly","K15074//BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein","OBS67400.1//hypothetical protein A6R68_04102 [Neotoma lepida]",4]
[389362,753,15.28,26.16,0.775717997462334,{"v":2.86384175501843e-07,"d":"2.86E-07"},"*",{"v":4.37626e-08,"d":"4.38E-08"},"PSMG4","GO:0000502//proteasome complex","NA","GO:0043248//proteasome assembly","K11878//proteasome assembly chaperone 4","NP_001122063.1//proteasome assembly chaperone 4 isoform b [Homo sapiens];NP_001122064.1//proteasome assembly chaperone 4 isoform a [Homo sapiens];NP_001129222.1//proteasome assembly chaperone 4 isoform c [Homo sapiens]","1//3"]
[12,1629,0.55,0.94,0.773229138152977,0.259415727996491,"*",0.1480914,"SERPINA3","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0072562//blood microparticle","GO:0004867//serine-type endopeptidase inhibitor activity","NA","K04525//serpin peptidase inhibitor, clade A","EAW81588.1//serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3, isoform CRA_b [Homo sapiens]",4]
[3866,1861,0.48,0.82,0.772589503896927,0.259444178942751,"*",0.1480914,"KRT15","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005882//intermediate filament","GO:0097110//scaffold protein binding;GO:0005198//structural molecule activity;GO:0005200//structural constituent of cytoskeleton","GO:0008544//epidermis development;GO:0031424//keratinization;GO:0070268//cornification","K07604//type I keratin, acidic","NP_002266.2//keratin, type I cytoskeletal 15 [Homo sapiens]","3//A2MP1"]
[114026,2627,0.48,0.82,0.772589503896927,0.131763628904665,"*",0.0650652,"ZIM3","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_012630316.1//zinc finger protein 568 isoform X1 [Microcebus murinus]","1//3"]
[124975,2254,1.81,3.09,0.771617140821169,0.0129979713054144,"*",0.00464376,"GGT6","GO:0070062//extracellular exosome;GO:0016021//integral component of membrane","GO:0102953//hypoglycin A gamma-glutamyl transpeptidase activity;GO:0036374//glutathione hydrolase activity","GO:0006751//glutathione catabolic process;GO:1901750//leukotriene D4 biosynthetic process;GO:0006750//glutathione biosynthetic process","K00681//gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]","NP_001275632.1//gamma-glutamyltransferase 6 isoform d [Homo sapiens];NP_001275633.1//gamma-glutamyltransferase 6 isoform e [Homo sapiens];NP_699169.2//gamma-glutamyltransferase 6 isoform b [Homo sapiens];NP_001116362.1//gamma-glutamyltransferase 6 isoform a [Homo sapiens];NP_001275631.1//gamma-glutamyltransferase 6 isoform c [Homo sapiens]","1//3;3//A2MP1;2//1"]
[353322,953,1.73,2.95,0.769942916612479,0.118745610307132,"*",0.0571204,"ANKRD37","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005739//mitochondrion","NA","NA","K15502//serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A","XP_016863665.1//PREDICTED: ankyrin repeat domain-containing protein 37 isoform X1 [Homo sapiens]","3//A2MP1"]
[118471,786,0.61,1.04,0.769702380578206,0.344608419681621,"*",0.208698,"PRAP1","GO:0005576//extracellular region","NA","NA","K21250//proline-rich acidic protein 1","NP_001138673.1//proline-rich acidic protein 1 isoform 2 precursor [Homo sapiens];NP_660203.3//proline-rich acidic protein 1 isoform 1 precursor [Homo sapiens]","1//3;4"]
[9590,8412,14.11,24.04,0.768718908113921,{"v":1.11221161385475E-59,"d":"1.11E-59"},"*",{"v":1.246312E-61,"d":"1.25E-61"},"AKAP12","GO:0005925//focal adhesion;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0051018//protein kinase A binding;GO:0008179//adenylate cyclase binding","GO:0006605//protein targeting;GO:0007165//signal transduction;GO:0090036//regulation of protein kinase C signaling;GO:0010739//positive regulation of protein kinase A signaling;GO:0030819//positive regulation of cAMP biosynthetic process","K16528//A-kinase anchor protein 12","XP_004044877.1//PREDICTED: A-kinase anchor protein 12 isoform X2 [Gorilla gorilla gorilla];XP_018885117.1//PREDICTED: A-kinase anchor protein 12 isoform X1 [Gorilla gorilla gorilla]","3//A2MP1;2//1"]
[389816,1212,1.82,3.1,0.768329765075542,0.0598990384281999,"*",0.025956,"LRRC26","GO:0070062//extracellular exosome;GO:0005856//cytoskeleton;GO:0005730//nucleolus;GO:0005887//integral component of plasma membrane;GO:0001650//fibrillar center;GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0008076//voltage-gated potassium channel complex","GO:0005249//voltage-gated potassium channel activity;GO:0044325//ion channel binding;GO:0015459//potassium channel regulator activity;GO:0099104//potassium channel activator activity","GO:0071805//potassium ion transmembrane transport;GO:1903818//positive regulation of voltage-gated potassium channel activity","K06838//slit 1","NP_001013675.1//leucine-rich repeat-containing protein 26 precursor [Homo sapiens]","2//1"]
[1847,2545,24.57,41.85,0.768329765075541,{"v":4.99700098507463e-32,"d":"5.00E-32"},"*",{"v":1.25754e-33,"d":"1.26E-33"},"DUSP5","NA","NA","NA","K04459//dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48]","EAW49559.1//dual specificity phosphatase 5, isoform CRA_a [Homo sapiens]","3//A2MP1"]
[152078,1124,0.3,0.51,0.765534746362977,0.539967103907482,"*",0.385826,"PQLC2L","GO:0016021//integral component of membrane","NA","NA","K05543//tRNA-dihydrouridine synthase 2 [EC:1.3.1.91]","NP_001230658.1//putative uncharacterized protein PQLC2L isoform 4 [Homo sapiens];NP_001123474.1//putative uncharacterized protein PQLC2L isoform 1 [Homo sapiens];NP_001093247.1//putative uncharacterized protein PQLC2L isoform 3 [Homo sapiens];NP_001123473.1//putative uncharacterized protein PQLC2L isoform 2 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[225689,1904,0.3,0.51,0.765534746362977,0.40277167888846,"*",0.26132,"MAPK15","GO:0005634//nucleus;GO:0005622//intracellular;GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0005524//ATP binding;GO:0017124//SH3 domain binding;GO:0004707//MAP kinase activity","GO:1904355//positive regulation of telomere capping;GO:0010468//regulation of gene expression;GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0051973//positive regulation of telomerase activity;GO:0046777//protein autophosphorylation","K19603//mitogen-activated protein kinase 15 [EC:2.7.11.24]","NP_620590.2//mitogen-activated protein kinase 15 [Homo sapiens]","2//1"]
[100507588,1256,1.3,2.21,0.765534746362977,0.118730158698764,"*",0.0571204,"TGFBR3L","GO:0016021//integral component of membrane","NA","NA","K05843//transforming growth factor, beta receptor III","NP_001182188.1//transforming growth factor-beta receptor type 3-like protein [Homo sapiens]","1//3"]
[27324,4711,0.1,0.17,0.765534746362977,0.482548038412292,"*",0.330298,"TOX3","GO:0005634//nucleus","GO:0003682//chromatin binding;GO:0042803//protein homodimerization activity;GO:0034056//estrogen response element binding;GO:0051219//phosphoprotein binding","GO:0043524//negative regulation of neuron apoptotic process;GO:0006351//transcription, DNA-templated;GO:0042981//regulation of apoptotic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006915//apoptotic process","K04650//nuclear receptor co-repressor 1","NP_001073899.2//TOX high mobility group box family member 3 isoform 1 [Homo sapiens];NP_001139660.1//TOX high mobility group box family member 3 isoform 2 [Homo sapiens]","3//A2MP1;2//1"]
[874,1128,5.29,8.98,0.763447722627121,0.000858914987525516,"*",0.00023707,"CBR3","GO:0005654//nucleoplasm;GO:0005615//extracellular space;GO:0005829//cytosol","GO:0070402//NADPH binding;GO:0004090//carbonyl reductase (NADPH) activity;GO:0000253//3-keto sterol reductase activity","GO:0042376//phylloquinone catabolic process;GO:0050890//cognition;GO:0006805//xenobiotic metabolic process","K00084//carbonyl reductase 3 [EC:1.1.1.184]","NP_001227.1//carbonyl reductase [NADPH] 3 [Homo sapiens]","3//A2MP1"]
[79078,1036,3.09,5.24,0.761959973633076,0.0215849434220532,"*",0.00817374,"C1orf50","NA","GO:0042802//identical protein binding","NA","NA","XP_003812918.1//PREDICTED: uncharacterized protein C1orf50 homolog [Pan paniscus]","3//A2MP1"]
[389161,2491,0.59,1,0.761213140412884,0.13005696711247,"*",0.0639212,"ANKUB1","NA","NA","NA","K04453//Max protein;K18492//insulin gene enhancer protein ISL-2","NP_001138432.1//protein ANKUB1 isoform 1 [Homo sapiens];XP_003826524.1//PREDICTED: protein ANKUB1 [Pan paniscus];NP_001302434.1//protein ANKUB1 isoform 2 [Homo sapiens]","1//3;2//1"]
[567,987,209.41,354.62,0.759943566985665,{"v":4.52304633402062e-99,"d":"4.52E-99"},"*",{"v":2.74656e-101,"d":"2.75E-101"},"B2M","GO:1990712//HFE-transferrin receptor complex;GO:0070062//extracellular exosome;GO:0042612//MHC class I protein complex;GO:0005925//focal adhesion;GO:0009897//external side of plasma membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol","GO:0042802//identical protein binding","GO:0033077//T cell differentiation in thymus;GO:0002237//response to molecule of bacterial origin;GO:0033216//ferric iron import;GO:1904440//positive regulation of ferrous iron import across plasma membrane;GO:0055072//iron ion homeostasis;GO:1904437//positive regulation of transferrin receptor binding;GO:0010977//negative regulation of neuron projection development;GO:0071283//cellular response to iron(III) ion;GO:1900121//negative regulation of receptor binding;GO:0045646//regulation of erythrocyte differentiation;GO:0001895//retina homeostasis;GO:0002481//antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent;GO:0019885//antigen processing and presentation of endogenous peptide antigen via MHC class I;GO:0071281//cellular response to iron ion;GO:1904434//positive regulation of ferrous iron binding;GO:0002726//positive regulation of T cell cytokine production;GO:0006955//immune response;GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0048260//positive regulation of receptor-mediated endocytosis;GO:0042026//protein refolding","K08055//beta-2-microglobulin","CAG33347.1//B2M [Homo sapiens]","2//1"]
[56956,2515,0.13,0.22,0.758991900496205,0.539777940444912,"*",0.385826,"LHX9","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003714//transcription corepressor activity;GO:0043565//sequence-specific DNA binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0035262//gonad morphogenesis;GO:0008585//female gonad development;GO:0008283//cell proliferation;GO:0006355//regulation of transcription, DNA-templated;GO:0008045//motor neuron axon guidance;GO:0008584//male gonad development","K09373//LIM homeobox protein 2/9","NP_001014434.1//LIM/homeobox protein Lhx9 isoform 2 [Homo sapiens];NP_064589.2//LIM/homeobox protein Lhx9 isoform 1 [Homo sapiens]","1//3;2//1"]
[7584,2664,1.44,2.43,0.754887502163469,0.0101355882293362,"*",0.00350818,"ZNF35","GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm","GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","NA","K09228//KRAB domain-containing zinc finger protein","XP_015996789.1//PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 35 [Rousettus aegyptiacus]","3//A2MP1"]
[4502,499,513.44,866.39,0.754820896512973,{"v":9.58607532195122e-115,"d":"9.59E-115"},"*",{"v":4.92086e-117,"d":"4.92E-117"},"MT2A","NA","NA","NA","K14739//metallothionein 1/2","XP_007981228.1//PREDICTED: metallothionein-2-like [Chlorocebus sabaeus]",4]
[7538,1752,121.87,205.39,0.75302291146953,{"v":1.59893069538462e-102,"d":"1.60E-102"},"*",{"v":9.10872e-105,"d":"9.11E-105"},"ZFP36","GO:0010494//cytoplasmic stress granule;GO:0005634//nucleus;GO:0000932//P-body;GO:0005737//cytoplasm;GO:0030014//CCR4-NOT complex;GO:1990904//ribonucleoprotein complex;GO:0005829//cytosol;GO:0030529//intracellular ribonucleoprotein complex","GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003677//DNA binding;GO:0017091//AU-rich element binding;GO:0031072//heat shock protein binding;GO:0019957//C-C chemokine binding;GO:0019901//protein kinase binding;GO:0071889//14-3-3 protein binding;GO:0046872//metal ion binding;GO:0070063//RNA polymerase binding;GO:0035925//mRNA 3'-UTR AU-rich region binding;GO:0019899//enzyme binding;GO:0003727//single-stranded RNA binding","GO:0038066//p38MAPK cascade;GO:0010837//regulation of keratinocyte proliferation;GO:0071222//cellular response to lipopolysaccharide;GO:0032680//regulation of tumor necrosis factor production;GO:0071356//cellular response to tumor necrosis factor;GO:0050728//negative regulation of inflammatory response;GO:1900153//positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0051028//mRNA transport;GO:1902172//regulation of keratinocyte apoptotic process;GO:0032897//negative regulation of viral transcription;GO:0031086//nuclear-transcribed mRNA catabolic process, deadenylation-independent decay;GO:0045647//negative regulation of erythrocyte differentiation;GO:0009611//response to wounding;GO:0045600//positive regulation of fat cell differentiation;GO:1904582//positive regulation of intracellular mRNA localization;GO:0070935//3'-UTR-mediated mRNA stabilization;GO:1904246//negative regulation of polynucleotide adenylyltransferase activity;GO:0071385//cellular response to glucocorticoid stimulus;GO:0045638//negative regulation of myeloid cell differentiation;GO:0045085//negative regulation of interleukin-2 biosynthetic process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0043488//regulation of mRNA stability;GO:1901835//positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA;GO:0000165//MAPK cascade;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0006402//mRNA catabolic process;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0061158//3'-UTR-mediated mRNA destabilization;GO:0045616//regulation of keratinocyte differentiation;GO:0042594//response to starvation;GO:0060213//positive regulation of nuclear-transcribed mRNA poly(A) tail shortening;GO:2000637//positive regulation of gene silencing by miRNA;GO:0035278//miRNA mediated inhibition of translation;GO:0097011//cellular response to granulocyte macrophage colony-stimulating factor stimulus","K15308//tristetraprolin","NP_003398.2//mRNA decay activator protein ZFP36 [Homo sapiens]","3//A2MP1"]
[7766,2419,0.63,1.06,0.750640531063283,0.139035176745354,"*",0.0693174,"ZNF223","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","AAF18684.1//ZNF155 [Homo sapiens]",5]
[107080638,2351,0.47,0.79,0.749191896499466,0.185211931054131,"*",0.0976728,"TBC1D7-LOC100130357","GO:0036064//ciliary basal body;GO:0031410//cytoplasmic vesicle","GO:0017137//Rab GTPase binding;GO:0005096//GTPase activator activity","GO:0032007//negative regulation of TOR signaling;GO:0090630//activation of GTPase activity;GO:0070848//response to growth factor;GO:0031398//positive regulation of protein ubiquitination;GO:1902018//negative regulation of cilium assembly","K20396//TBC1 domain family member 7","XP_003263567.1//PREDICTED: TBC1 domain family member 7 isoform X2 [Nomascus leucogenys]","1//3"]
[51330,1048,217.24,364.95,0.748409052622747,{"v":1.04964966070588E-105,"d":"1.05E-105"},"*",{"v":5.58534e-108,"d":"5.59E-108"},"TNFRSF12A","GO:0001726//ruffle;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","NA","GO:0097191//extrinsic apoptotic signaling pathway;GO:0001525//angiogenesis;GO:0061041//regulation of wound healing;GO:0045773//positive regulation of axon extension;GO:0006931//substrate-dependent cell migration, cell attachment to substrate;GO:0043065//positive regulation of apoptotic process;GO:0045765//regulation of angiogenesis;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:0033209//tumor necrosis factor-mediated signaling pathway","K05149//tumor necrosis factor receptor superfamily member 12A","XP_016784722.1//PREDICTED: tumor necrosis factor receptor superfamily member 12A [Pan troglodytes]","2//1"]
[79663,1972,1.87,3.14,0.747726289003991,0.0139071861527729,"*",0.0049921,"HSPBAP1","GO:0005737//cytoplasm","NA","NA","K19375//HSPB1-associated protein 1","EHH16122.1//hypothetical protein EGK_11362 [Macaca mulatta];NP_078886.2//HSPB1-associated protein 1 isoform 1 [Homo sapiens]","1//3;5"]
[3669,1584,2.18,3.66,0.747515513507116,0.0672317804982206,"*",0.029567,"ISG20","GO:0016605//PML body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0015030//Cajal body;GO:0005737//cytoplasm","GO:0034511//U3 snoRNA binding;GO:0008310//single-stranded DNA 3'-5' exodeoxyribonuclease activity;GO:0000175//3'-5'-exoribonuclease activity;GO:0003676//nucleic acid binding;GO:0004527//exonuclease activity;GO:0046872//metal ion binding;GO:0030620//U2 snRNA binding;GO:0030619//U1 snRNA binding;GO:0008859//exoribonuclease II activity","GO:0006401//RNA catabolic process;GO:0060337//type I interferon signaling pathway;GO:0008283//cell proliferation;GO:0045071//negative regulation of viral genome replication;GO:0000738//DNA catabolic process, exonucleolytic;GO:0051607//defense response to virus;GO:0006364//rRNA processing;GO:0009615//response to virus","K12579//interferon-stimulated gene 20 kDa protein [EC:3.1.13.1]","NP_001290166.1//interferon-stimulated gene 20 kDa protein isoform c [Homo sapiens];NP_002192.2//interferon-stimulated gene 20 kDa protein isoform a [Homo sapiens];BAD92876.1//interferon stimulated gene 20kDa variant, partial [Homo sapiens]","1//3;5"]
[23645,2399,43.73,73.37,0.746566936740675,{"v":5.20276637575758e-50,"d":"5.20E-50"},"*",{"v":7.52372e-52,"d":"7.52E-52"},"PPP1R15A","GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0005741//mitochondrial outer membrane;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0000164//protein phosphatase type 1 complex;GO:0005789//endoplasmic reticulum membrane;GO:0005739//mitochondrion","GO:0019888//protein phosphatase regulator activity;GO:0072542//protein phosphatase activator activity;GO:0008157//protein phosphatase 1 binding;GO:0019901//protein kinase binding","GO:1903898//negative regulation of PERK-mediated unfolded protein response;GO:0032515//negative regulation of phosphoprotein phosphatase activity;GO:0034976//response to endoplasmic reticulum stress;GO:0007050//cell cycle arrest;GO:1990441//negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress;GO:0006974//cellular response to DNA damage stimulus;GO:0030968//endoplasmic reticulum unfolded protein response;GO:1902310//positive regulation of peptidyl-serine dephosphorylation;GO:0032516//positive regulation of phosphoprotein phosphatase activity;GO:0070972//protein localization to endoplasmic reticulum;GO:1903917//positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation;GO:0036496//regulation of translational initiation by eIF2 alpha dephosphorylation;GO:1903912//negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation;GO:0032058//positive regulation of translational initiation in response to stress;GO:0006915//apoptotic process;GO:0070262//peptidyl-serine dephosphorylation;GO:0035308//negative regulation of protein dephosphorylation;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0045943//positive regulation of transcription from RNA polymerase I promoter;GO:0060734//regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation","K14019//protein phosphatase 1 regulatory subunit 15A","NP_055145.3//protein phosphatase 1 regulatory subunit 15A [Homo sapiens]","3//A2MP1"]
[64859,3855,3.55,5.94,0.742643906408721,{"v":6.60559976991838e-07,"d":"6.61E-07"},"*",{"v":1.063992E-7,"d":"1.06E-07"},"NABP1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000784//nuclear chromosome, telomeric region;GO:0005829//cytosol;GO:0070876//SOSS complex","GO:0003697//single-stranded DNA binding;GO:0003723//RNA binding","GO:0007093//mitotic cell cycle checkpoint;GO:0042795//snRNA transcription from RNA polymerase II promoter;GO:0010212//response to ionizing radiation;GO:0006281//DNA repair;GO:0000724//double-strand break repair via homologous recombination;GO:0006974//cellular response to DNA damage stimulus","K15280//solute carrier family 35, member C2","NP_001026886.1//SOSS complex subunit B2 isoform 1 [Homo sapiens]","1//3;2//1"]
[715,2625,20.22,33.82,0.742093662506969,{"v":6.85612052762923e-25,"d":"6.86E-25"},"*",{"v":2.40784e-26,"d":"2.41E-26"},"C1R","NA","NA","NA","K01330//complement component 1, r subcomponent [EC:3.4.21.41]","NP_001341275.1//complement C1r subcomponent isoform 2 preproprotein [Homo sapiens];NP_001724.4//complement C1r subcomponent isoform 1 preproprotein [Homo sapiens]","1//3;5"]
[373156,1113,82.21,137.46,0.741626065786125,{"v":7.83226055652174e-47,"d":"7.83E-47"},"*",{"v":1.240492E-48,"d":"1.24E-48"},"GSTK1","GO:0005759//mitochondrial matrix;GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005743//mitochondrial inner membrane;GO:0005622//intracellular;GO:0005777//peroxisome","GO:0015035//protein disulfide oxidoreductase activity;GO:0004364//glutathione transferase activity;GO:0004602//glutathione peroxidase activity;GO:0016740//transferase activity;GO:0005102//receptor binding","GO:0006749//glutathione metabolic process;GO:1901687//glutathione derivative biosynthetic process;GO:0030855//epithelial cell differentiation","K13299//glutathione S-transferase kappa 1 [EC:2.5.1.18]","NP_057001.1//glutathione S-transferase kappa 1 isoform a [Homo sapiens];NP_001137153.1//glutathione S-transferase kappa 1 isoform d [Homo sapiens];NP_001137151.1//glutathione S-transferase kappa 1 isoform b [Homo sapiens];NP_001137152.1//glutathione S-transferase kappa 1 isoform c [Homo sapiens]","1//3;2//1"]
[6722,3630,16.09,26.85,0.738757762149329,{"v":3.82665924721754e-24,"d":"3.83E-24"},"*",{"v":1.420564E-25,"d":"1.42E-25"},"SRF","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000790//nuclear chromatin;GO:0005737//cytoplasm","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0001076//transcription factor activity, RNA polymerase II transcription factor binding;GO:0070878//primary miRNA binding;GO:0042826//histone deacetylase binding;GO:0031490//chromatin DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0000983//transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding;GO:0003705//transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding;GO:0010736//serum response element binding;GO:0042803//protein homodimerization activity;GO:0046983//protein dimerization activity;GO:0000982//transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0000987//proximal promoter sequence-specific DNA binding;GO:0008134//transcription factor binding","GO:1902895//positive regulation of pri-miRNA transcription from RNA polymerase II promoter;GO:0021766//hippocampus development;GO:0060055//angiogenesis involved in wound healing;GO:0060534//trachea cartilage development;GO:0030878//thyroid gland development;GO:0060292//long term synaptic depression;GO:0008285//negative regulation of cell proliferation;GO:0022028//tangential migration from the subventricular zone to the olfactory bulb;GO:0007160//cell-matrix adhesion;GO:0071333//cellular response to glucose stimulus;GO:0001764//neuron migration;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0001569//branching involved in blood vessel morphogenesis;GO:0055003//cardiac myofibril assembly;GO:0034097//response to cytokine;GO:0030168//platelet activation;GO:0090009//primitive streak formation;GO:0045773//positive regulation of axon extension;GO:0001707//mesoderm formation;GO:0048821//erythrocyte development;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0090398//cellular senescence;GO:0030220//platelet formation;GO:1900222//negative regulation of amyloid-beta clearance;GO:0060218//hematopoietic stem cell differentiation;GO:0045214//sarcomere organization;GO:0060947//cardiac vascular smooth muscle cell differentiation;GO:0006351//transcription, DNA-templated;GO:0001701//in utero embryonic development;GO:0046716//muscle cell cellular homeostasis;GO:0045059//positive thymic T cell selection;GO:0043149//stress fiber assembly;GO:0043589//skin morphogenesis;GO:0060425//lung morphogenesis;GO:0001829//trophectodermal cell differentiation;GO:0060324//face development;GO:0003257//positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation;GO:0045597//positive regulation of cell differentiation;GO:0090136//epithelial cell-cell adhesion;GO:0035912//dorsal aorta morphogenesis;GO:0001666//response to hypoxia;GO:0045987//positive regulation of smooth muscle contraction;GO:0060532//bronchus cartilage development;GO:0010735//positive regulation of transcription via serum response element binding;GO:0070830//bicellular tight junction assembly;GO:0010669//epithelial structure maintenance;GO:1902894//negative regulation of pri-miRNA transcription from RNA polymerase II promoter;GO:0046016//positive regulation of transcription by glucose;GO:0042789//mRNA transcription from RNA polymerase II promoter;GO:0007616//long-term memory;GO:0002011//morphogenesis of an epithelial sheet;GO:0002042//cell migration involved in sprouting angiogenesis;GO:0031175//neuron projection development;GO:0030155//regulation of cell adhesion;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter;GO:0035855//megakaryocyte development;GO:0051491//positive regulation of filopodium assembly;GO:0061029//eyelid development in camera-type eye;GO:0048538//thymus development;GO:0030336//negative regulation of cell migration;GO:0061145//lung smooth muscle development;GO:0001947//heart looping;GO:0008306//associative learning;GO:0033561//regulation of water loss via skin;GO:0060347//heart trabecula formation;GO:0048589//developmental growth;GO:0009725//response to hormone","K04378//serum response factor","XP_017733675.1//PREDICTED: serum response factor isoform X2 [Rhinopithecus bieti];NP_003122.1//serum response factor isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[55080,1834,2.5,4.17,0.738119288782576,0.0059352121703916,"*",1.945088E-3,"TAPBPL","GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0000139//Golgi membrane","GO:0032403//protein complex binding","GO:0002376//immune system process;GO:0002590//negative regulation of antigen processing and presentation of peptide antigen via MHC class I","K08058//TAP binding protein (tapasin)","NP_060479.3//tapasin-related protein precursor [Homo sapiens]","4;1//3"]
[7975,3350,30.35,50.62,0.738010990967639,{"v":1.54782865203252e-47,"d":"1.55E-47"},"*",{"v":2.38366e-49,"d":"2.38E-49"},"MAFK","NA","NA","NA","K09037//transcription factor MAFF/G/K","XP_014201039.1//PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein LOC106634934 [Pan paniscus]","3//A2MP1"]
[2814,3493,0.06,0.1,0.736965594166206,0.609452303506548,"*",0.451538,"GP5","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005578//proteinaceous extracellular matrix","NA","GO:0007155//cell adhesion;GO:0007596//blood coagulation;GO:0007597//blood coagulation, intrinsic pathway;GO:0030168//platelet activation;GO:0007409//axonogenesis","K06260//platelet glycoprotein V","NP_004479.1//platelet glycoprotein V precursor [Homo sapiens]","2//1"]
[320,6603,0.06,0.1,0.736965594166206,0.57888458556701,"*",0.421824,"APBA1","GO:0016020//membrane;GO:0005634//nucleus;GO:0008021//synaptic vesicle;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm;GO:0043005//neuron projection","GO:0001540//amyloid-beta binding","GO:0007399//nervous system development;GO:0010468//regulation of gene expression;GO:0008088//axo-dendritic transport;GO:0001701//in utero embryonic development;GO:0014051//gamma-aminobutyric acid secretion;GO:0035264//multicellular organism growth;GO:0006886//intracellular protein transport;GO:0007269//neurotransmitter secretion;GO:0007155//cell adhesion;GO:0007626//locomotory behavior;GO:0007268//chemical synaptic transmission;GO:0006461//protein complex assembly;GO:0014047//glutamate secretion","K04531//amyloid beta A4 precursor protein-binding family A member 1","NP_001154.2//amyloid beta A4 precursor protein-binding family A member 1 [Homo sapiens]","3//A2MP1"]
[246176,3031,0.03,0.05,0.736965594166206,0.735313432157094,"*",0.623548,"GAS2L2","GO:0005856//cytoskeleton;GO:0005737//cytoplasm","GO:0051015//actin filament binding;GO:0008017//microtubule binding;GO:0008093//cytoskeletal adaptor activity","GO:0007026//negative regulation of microtubule depolymerization;GO:0001578//microtubule bundle formation","K17953//cytochrome P450 family 31 subfamily A;K10382//dystonin;K13209//RNA-binding protein EWS","NP_644814.1//GAS2-like protein 2 [Homo sapiens]","3//A2MP1"]
[100130742,1323,0.06,0.1,0.736965594166206,1.00655049864328,"*",0.998548,"LRRC69","NA","NA","NA","K18342//OTU domain-containing protein 6 [EC:3.4.19.12];K16175//protein scribble","NP_001123362.1//leucine-rich repeat-containing protein 69 isoform 1 [Homo sapiens];NP_001341399.1//leucine-rich repeat-containing protein 69 isoform 2 [Homo sapiens]","1//3"]
[89874,3947,0.3,0.5,0.736965594166206,0.717857193865396,"*",0.603622,"SLC25A21","GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane","GO:0005310//dicarboxylic acid transmembrane transporter activity;GO:0015139//alpha-ketoglutarate transmembrane transporter activity","GO:0055085//transmembrane transport;GO:0006835//dicarboxylic acid transport;GO:0006554//lysine catabolic process;GO:0006839//mitochondrial transport","K15110//solute carrier family 25 (mitochondrial 2-oxodicarboxylate transporter), member 21","NP_001164641.1//mitochondrial 2-oxodicarboxylate carrier isoform 2 [Homo sapiens];NP_085134.1//mitochondrial 2-oxodicarboxylate carrier isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[51294,6579,0.06,0.1,0.736965594166206,0.578685724493301,"*",0.421824,"PCDH12","GO:0070062//extracellular exosome;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0005886//plasma membrane","GO:0005509//calcium ion binding","GO:0060711//labyrinthine layer development;GO:0005977//glycogen metabolic process;GO:0007155//cell adhesion;GO:0008038//neuron recognition;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007267//cell-cell signaling;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules","K16499//protocadherin delta 2","NP_057664.1//protocadherin-12 precursor [Homo sapiens]","3//A2MP1"]
[51351,6404,0.12,0.2,0.736965594166206,0.28755918832274,"*",0.1671098,"ZNF117","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_018886338.1//PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 107-like [Gorilla gorilla gorilla]","3//A2MP1"]
[164312,2982,0.03,0.05,0.736965594166206,0.733472441237113,"*",0.623548,"LRRN4","GO:0070062//extracellular exosome;GO:0005887//integral component of plasma membrane","NA","GO:0008542//visual learning;GO:0007616//long-term memory","K16360//netrin-G3 ligand","NP_689824.2//leucine-rich repeat neuronal protein 4 precursor [Homo sapiens]",4]
[5156,4004,0.03,0.05,0.736965594166206,1.0111605819012,"*",0.998184,"PDGFRA","GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0030054//cell junction;GO:0005737//cytoplasm","GO:0048407//platelet-derived growth factor binding;GO:0005524//ATP binding;GO:0005018//platelet-derived growth factor alpha-receptor activity;GO:0046934//phosphatidylinositol-4,5-bisphosphate 3-kinase activity","GO:0001775//cell activation;GO:0060326//cell chemotaxis;GO:0030325//adrenal gland development;GO:0055003//cardiac myofibril assembly","K04363//platelet-derived growth factor receptor alpha [EC:2.7.10.1]","NP_001334759.1//platelet-derived growth factor receptor alpha isoform 4 [Homo sapiens];NP_001334757.1//platelet-derived growth factor receptor alpha isoform 3 [Homo sapiens];XP_006714104.1//PREDICTED: platelet-derived growth factor receptor alpha isoform X4 [Homo sapiens]","1//3;5"]
[10418,5154,0.03,0.05,0.736965594166206,0.780639167842634,"*",0.685686,"SPON1","NA","NA","NA","K13912//deleted in malignant brain tumors 1 protein;K16857//thrombospondin 1","XP_508295.3//PREDICTED: spondin-1 [Pan troglodytes]","3//A2MP1"]
[347688,1504,0.03,0.05,0.736965594166206,0.641572407887324,"*",0.499032,"TUBB8","GO:0005874//microtubule;GO:0005737//cytoplasm","GO:0005200//structural constituent of cytoskeleton;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0007017//microtubule-based process","K07375//tubulin beta","A6NNZ2.1//RecName: Full=Tubulin beta-8 chain-like protein LOC260334","2//1"]
[51440,4670,0.03,0.05,0.736965594166206,0.780305490061979,"*",0.685686,"HPCAL4","NA","GO:0005509//calcium ion binding;GO:0005246//calcium channel regulator activity","GO:0007165//signal transduction","K19936//visinin-like protein 1","XP_010624191.1//PREDICTED: hippocalcin-like protein 4 isoform X1 [Fukomys damarensis];OXB56417.1//hypothetical protein ASZ78_010671, partial [Callipepla squamata];NP_001269326.1//hippocalcin-like protein 4 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[23166,7965,0.03,0.05,0.736965594166206,0.628509440970602,"*",0.505908,"STAB1","NA","NA","NA","K19020//stabilin-1","XP_005265031.1//PREDICTED: stabilin-1 isoform X6 [Homo sapiens]","2//1"]
[27033,2108,0.27,0.45,0.736965594166206,1.018769645087,"*",0.996958,"ZBTB32","GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0008270//zinc ion binding;GO:0003676//nucleic acid binding","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0042769//DNA damage response, detection of DNA damage;GO:0036297//interstrand cross-link repair;GO:0006366//transcription from RNA polymerase II promoter","K10506//zinc finger and BTB domain-containing protein 32","XP_016882081.1//PREDICTED: zinc finger and BTB domain-containing protein 32 isoform X5 [Homo sapiens];NP_001303831.1//zinc finger and BTB domain-containing protein 32 isoform 2 [Homo sapiens];NP_055198.1//zinc finger and BTB domain-containing protein 32 isoform 1 [Homo sapiens]","1//3;2//1"]
[58512,3856,0.21,0.35,0.736965594166206,0.309439972005497,"*",0.1832348,"DLGAP3","GO:0030054//cell junction;GO:0045202//synapse;GO:0014069//postsynaptic density;GO:0005886//plasma membrane;GO:0045211//postsynaptic membrane","GO:0001540//amyloid-beta binding;GO:0019904//protein domain specific binding","GO:0023052//signaling;GO:0006461//protein complex assembly","K15008//discs, large-associated protein 1","NP_001073887.1//disks large-associated protein 3 [Homo sapiens]","2//1"]
[57593,2931,0.98,1.63,0.734018310115869,0.0347613091304348,"*",0.0140142,"EBF4","GO:0005634//nucleus","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0008134//transcription factor binding","GO:0007275//multicellular organism development","K09103//early B-cell factor","XP_017360238.1//PREDICTED: transcription factor COE4 isoform X1 [Cebus capucinus imitator]","1//3"]
[116986,4957,4.17,6.93,0.73280796869255,{"v":8.9426898647289e-10,"d":"8.94E-10"},"*",{"v":1.001532E-10,"d":"1.00E-10"},"AGAP2","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005739//mitochondrion","GO:0046872//metal ion binding;GO:0030295//protein kinase activator activity;GO:0005525//GTP binding;GO:0019901//protein kinase binding;GO:0003924//GTPase activity;GO:0005096//GTPase activator activity","GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0042177//negative regulation of protein catabolic process;GO:0043524//negative regulation of neuron apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0046427//positive regulation of JAK-STAT cascade;GO:0060749//mammary gland alveolus development;GO:0033601//positive regulation of mammary gland epithelial cell proliferation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0015031//protein transport","K17848//Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2","NP_055585.1//arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 isoform PIKE-A [Homo sapiens];NP_001116244.1//arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 isoform PIKE-L [Homo sapiens]","3//A2MP1;2//1"]
[83938,857,2.04,3.39,0.732716121164849,0.126870976576577,"*",0.061712,"LRMDA","NA","NA","GO:0030318//melanocyte differentiation","K11092//U2 small nuclear ribonucleoprotein A'","XP_015002715.1//PREDICTED: leucine-rich repeat-containing protein C10orf11 homolog [Macaca mulatta];NP_114413.1//leucine-rich melanocyte differentiation-associated protein isoform 2 [Homo sapiens]","1//3;4"]
[1482,1760,10.46,17.34,0.729221046974894,{"v":5.81545084205817e-08,"d":"5.82E-08"},"*",{"v":8.13668e-09,"d":"8.14E-09"},"NKX2-5","GO:0090575//RNA polymerase II transcription factor complex;GO:0032991//macromolecular complex;GO:0005634//nucleus;GO:0005667//transcription factor complex;GO:0032993//protein-DNA complex;GO:0005737//cytoplasm","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0046982//protein heterodimerization activity;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003705//transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding;GO:0010736//serum response element binding;GO:0042803//protein homodimerization activity;GO:0001190//transcriptional activator activity, RNA polymerase II transcription factor binding;GO:0003682//chromatin binding;GO:0043565//sequence-specific DNA binding;GO:0008134//transcription factor binding","GO:0003148//outflow tract septum morphogenesis;GO:0060412//ventricular septum morphogenesis;GO:0045666//positive regulation of neuron differentiation;GO:0010667//negative regulation of cardiac muscle cell apoptotic process;GO:0007512//adult heart development;GO:0051891//positive regulation of cardioblast differentiation;GO:0003211//cardiac ventricle formation;GO:0030878//thyroid gland development;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0060048//cardiac muscle contraction;GO:0001570//vasculogenesis;GO:0003166//bundle of His development;GO:0010832//negative regulation of myotube differentiation;GO:0003221//right ventricular cardiac muscle tissue morphogenesis;GO:0060037//pharyngeal system development;GO:0055014//atrial cardiac muscle cell development;GO:0060928//atrioventricular node cell development;GO:0055117//regulation of cardiac muscle contraction;GO:0030509//BMP signaling pathway;GO:0010765//positive regulation of sodium ion transport;GO:0003151//outflow tract morphogenesis;GO:0003285//septum secundum development;GO:0010735//positive regulation of transcription via serum response element binding;GO:0060070//canonical Wnt signaling pathway;GO:0003168//Purkinje myocyte differentiation;GO:0003222//ventricular trabecula myocardium morphogenesis;GO:0060038//cardiac muscle cell proliferation;GO:0048536//spleen development;GO:0060971//embryonic heart tube left/right pattern formation;GO:0030097//hemopoiesis;GO:0060043//regulation of cardiac muscle cell proliferation;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter;GO:1903779//regulation of cardiac conduction;GO:0003350//pulmonary myocardium development;GO:0045214//sarcomere organization;GO:0060929//atrioventricular node cell fate commitment;GO:0003278//apoptotic process involved in heart morphogenesis;GO:0045823//positive regulation of heart contraction;GO:0055005//ventricular cardiac myofibril assembly;GO:0001947//heart looping;GO:0060413//atrial septum morphogenesis;GO:0003342//proepicardium development;GO:0060347//heart trabecula formation;GO:0008284//positive regulation of cell proliferation","K09345//homeobox protein Nkx-2.5","XP_004697192.1//PREDICTED: homeobox protein Nkx-2.5 [Echinops telfairi];NP_004378.1//homeobox protein Nkx-2.5 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[9997,1030,19.16,31.76,0.729113351406778,{"v":3.11148660357518e-09,"d":"3.11E-09"},"*",{"v":3.7048E-10,"d":"3.70E-10"},"SCO2","GO:0005759//mitochondrial matrix;GO:0005743//mitochondrial inner membrane;GO:0030016//myofibril;GO:0005739//mitochondrion","GO:0005507//copper ion binding","GO:0003012//muscle system process;GO:0001654//eye development;GO:0006878//cellular copper ion homeostasis;GO:0014823//response to activity;GO:0001701//in utero embryonic development;GO:0008535//respiratory chain complex IV assembly;GO:0055114//oxidation-reduction process;GO:0006825//copper ion transport;GO:0045454//cell redox homeostasis;GO:0022904//respiratory electron transport chain","K07152//protein SCO1/2","XP_001116350.3//PREDICTED: protein SCO2 homolog, mitochondrial [Macaca mulatta];XP_011753064.1//PREDICTED: uncharacterized protein LOC105489744 isoform X1 [Macaca nemestrina];NP_005129.2//protein SCO2 homolog, mitochondrial precursor [Homo sapiens]","1//3;2//1"]
[51284,4992,0.49,0.81,0.725140158769417,0.0618302896333573,"*",0.0269206,"TLR7","GO:0016021//integral component of membrane","GO:0004888//transmembrane signaling receptor activity;GO:0003727//single-stranded RNA binding","GO:0034154//toll-like receptor 7 signaling pathway;GO:0051607//defense response to virus;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0045087//innate immune response","K05404//toll-like receptor 7","AAZ99026.1//TLR7 [Homo sapiens]","3//A2MP1"]
[7706,5744,15.62,25.78,0.722857810219672,{"v":2.55935534849498e-40,"d":"2.56E-40"},"*",{"v":4.79058e-42,"d":"4.79E-42"},"TRIM25","GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0005829//cytosol","GO:0003723//RNA binding;GO:0008270//zinc ion binding;GO:1904264//ubiquitin protein ligase activity involved in ERAD pathway;GO:0003700//DNA binding transcription factor activity;GO:0004842//ubiquitin-protein transferase activity;GO:0016874//ligase activity;GO:0045296//cadherin binding","GO:0046597//negative regulation of viral entry into host cell;GO:0043627//response to estrogen;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0036503//ERAD pathway;GO:0016579//protein deubiquitination;GO:0045087//innate immune response;GO:0060333//interferon-gamma-mediated signaling pathway;GO:1902186//regulation of viral release from host cell;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0006513//protein monoubiquitination;GO:0051607//defense response to virus;GO:1902187//negative regulation of viral release from host cell;GO:0016032//viral process;GO:0033280//response to vitamin D;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0019985//translesion synthesis;GO:1990830//cellular response to leukemia inhibitory factor;GO:0046596//regulation of viral entry into host cell;GO:0032480//negative regulation of type I interferon production","K10652//tripartite motif-containing protein 25 [EC:2.3.2.27]","BAD92231.1//tripartite motif-containing 25 variant, partial [Homo sapiens]",4]
[8416,1843,0.74,1.22,0.721283971933937,0.192719564000471,"*",0.1024162,"ANXA9","GO:0070062//extracellular exosome;GO:0009986//cell surface;GO:0005829//cytosol","GO:0005544//calcium-dependent phospholipid binding;GO:0005509//calcium ion binding;GO:0001786//phosphatidylserine binding;GO:0015464//acetylcholine receptor activity","GO:0098609//cell-cell adhesion","K17090//annexin A9","XP_017401806.1//PREDICTED: annexin A9 isoform X1 [Cebus capucinus imitator]","2//1"]
[150696,4719,0.91,1.5,0.721024050297185,0.0113627323252496,"*",0.00398912,"PROM2","GO:0071914//prominosome;GO:0070062//extracellular exosome;GO:0009986//cell surface;GO:0042995//cell projection;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","NA","GO:0043087//regulation of GTPase activity;GO:0001934//positive regulation of protein phosphorylation;GO:0031346//positive regulation of cell projection organization;GO:0048550//negative regulation of pinocytosis;GO:2001287//negative regulation of caveolin-mediated endocytosis","K15602//prominin 2","AAM10541.1//prominin-2 variant A [Homo sapiens]","1//3;3//A2MP1;2//1"]
[144110,3676,0.17,0.28,0.719892080807265,0.430093442970822,"*",0.284216,"TMEM86A","GO:0016021//integral component of membrane","NA","NA","K18575//alkenylglycerophosphocholine hydrolase [EC:3.3.2.2]","XP_004415708.2//PREDICTED: LOW QUALITY PROTEIN: lysoplasmalogenase-like protein TMEM86A [Odobenus rosmarus divergens]","2//1"]
[2859,1656,0.34,0.56,0.719892080807265,0.176879162352941,"*",0.0922376,"GPR35","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004930//G-protein coupled receptor activity;GO:0016494//C-X-C chemokine receptor activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway;GO:0070098//chemokine-mediated signaling pathway;GO:1901386//negative regulation of voltage-gated calcium channel activity;GO:0035025//positive regulation of Rho protein signal transduction;GO:0007010//cytoskeleton organization;GO:1904456//negative regulation of neuronal action potential;GO:0007204//positive regulation of cytosolic calcium ion concentration","K04276//G protein-coupled receptor 35","NP_001182310.1//G-protein coupled receptor 35 isoform b [Homo sapiens];XP_003813126.1//PREDICTED: G-protein coupled receptor 35 isoform X1 [Pan paniscus]","1//3;3//A2MP1"]
[9564,4132,44.68,73.51,0.718311335815838,{"v":3.22811351935484e-80,"d":"3.23E-80"},"*",{"v":2.50586e-82,"d":"2.51E-82"},"BCAR1","GO:0001726//ruffle;GO:0005925//focal adhesion;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0005886//plasma membrane;GO:0030027//lamellipodium;GO:0005737//cytoplasm","GO:0004871//signal transducer activity;GO:0017124//SH3 domain binding;GO:0019901//protein kinase binding","GO:0016477//cell migration;GO:0030335//positive regulation of cell migration;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0008286//insulin receptor signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0010595//positive regulation of endothelial cell migration;GO:0048012//hepatocyte growth factor receptor signaling pathway;GO:0007015//actin filament organization;GO:0008283//cell proliferation;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0060326//cell chemotaxis;GO:0007229//integrin-mediated signaling pathway;GO:0001558//regulation of cell growth;GO:0050853//B cell receptor signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway;GO:0035729//cellular response to hepatocyte growth factor stimulus;GO:0050852//T cell receptor signaling pathway;GO:0007155//cell adhesion;GO:0051301//cell division;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0042981//regulation of apoptotic process;GO:0050851//antigen receptor-mediated signaling pathway","K05726//breast cancer anti-estrogen resistance 1","NP_001164189.1//breast cancer anti-estrogen resistance protein 1 isoform 5 [Homo sapiens];NP_001164187.1//breast cancer anti-estrogen resistance protein 1 isoform 3 [Homo sapiens];NP_001164186.1//breast cancer anti-estrogen resistance protein 1 isoform 2 [Homo sapiens];NP_001164185.1//breast cancer anti-estrogen resistance protein 1 isoform 1 [Homo sapiens];XP_007992273.1//PREDICTED: breast cancer anti-estrogen resistance protein 1 isoform X1 [Chlorocebus sabaeus];NP_001164190.1//breast cancer anti-estrogen resistance protein 1 isoform 7 [Homo sapiens];NP_001164191.1//breast cancer anti-estrogen resistance protein 1 isoform 8 [Homo sapiens]","4;2//1"]
[100128071,716,2,3.29,0.718087583960517,0.192742268944392,"*",0.1024162,"FAM229A","NA","NA","NA","NA","NP_001161148.1//protein FAM229A [Homo sapiens]","1//3"]
[5348,575,0.45,0.74,0.717600269299275,0.62894967639505,"*",0.505908,"FXYD1","GO:0042383//sarcolemma;GO:0016021//integral component of membrane","GO:0005216//ion channel activity;GO:0017080//sodium channel regulator activity","GO:2000649//regulation of sodium ion transmembrane transporter activity;GO:1903278//positive regulation of sodium ion export across plasma membrane;GO:0086036//regulation of cardiac muscle cell membrane potential","K13363//FXYD domain-containing ion transport regulator 6;K13360//FXYD domain-containing ion transport regulator 1","XP_002920972.1//PREDICTED: phospholemman [Ailuropoda melanoleuca]","1//3;4;3//A2MP1"]
[6876,3882,4.56,7.49,0.715931894294009,{"v":3.17783502037037e-08,"d":"3.18E-08"},"*",{"v":4.29706e-09,"d":"4.30E-09"},"TAGLN","GO:0005737//cytoplasm","GO:0051015//actin filament binding","GO:0007517//muscle organ development;GO:0030855//epithelial cell differentiation","K20526//transgelin","EAW67300.1//transgelin, isoform CRA_c [Homo sapiens]","4;2//1"]
[26353,2056,7.49,12.29,0.714447291913911,{"v":2.42966979281882e-07,"d":"2.43E-07"},"*",{"v":3.68542e-08,"d":"3.69E-08"},"HSPB8","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005737//cytoplasm","GO:0042802//identical protein binding","GO:1900034//regulation of cellular response to heat","K08879//heat shock protein beta-8","NP_055180.1//heat shock protein beta-8 [Homo sapiens]","2//1"]
[9746,4029,13.6,22.31,0.714083862106439,{"v":3.57067469594595e-24,"d":"3.57E-24"},"*",{"v":1.3233e-25,"d":"1.32E-25"},"CLSTN3","GO:0070062//extracellular exosome;GO:0009986//cell surface;GO:0043234//protein complex;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0014069//postsynaptic density;GO:0045211//postsynaptic membrane;GO:0000139//Golgi membrane","GO:0005509//calcium ion binding","GO:0001558//regulation of cell growth;GO:0050806//positive regulation of synaptic transmission;GO:1902474//positive regulation of protein localization to synapse;GO:0051965//positive regulation of synapse assembly;GO:0007416//synapse assembly;GO:0051932//synaptic transmission, GABAergic;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0035249//synaptic transmission, glutamatergic","K04601//cadherin EGF LAG seven-pass G-type receptor 2;K16494//protocadherin beta","XP_017747257.1//PREDICTED: calsyntenin-3 isoform X1 [Rhinopithecus bieti]","3//A2MP1"]
[9744,2523,0.25,0.41,0.713695814843359,0.430052702851189,"*",0.284216,"ACAP1","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0055038//recycling endosome membrane","GO:0046872//metal ion binding;GO:0005096//GTPase activator activity","GO:0015031//protein transport","K12489//Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein","XP_008994854.2//PREDICTED: arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 isoform X1 [Callithrix jacchus]","3//A2MP1"]
[634,3393,0.75,1.23,0.713695814843359,0.0526038324776295,"*",0.022449,"CEACAM1","GO:0030658//transport vesicle membrane;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0030054//cell junction;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0016021//integral component of membrane;GO:0016328//lateral plasma membrane;GO:0070821//tertiary granule membrane;GO:0005886//plasma membrane;GO:0070062//extracellular exosome;GO:0005912//adherens junction;GO:0009925//basal plasma membrane;GO:0009986//cell surface;GO:0035579//specific granule membrane;GO:0031528//microvillus membrane","GO:1990782//protein tyrosine kinase binding;GO:0019903//protein phosphatase binding;GO:0042803//protein homodimerization activity;GO:0046983//protein dimerization activity;GO:0003779//actin binding;GO:0015125//bile acid transmembrane transporter activity;GO:0019900//kinase binding;GO:0005516//calmodulin binding;GO:0031005//filamin binding","GO:1903670//regulation of sprouting angiogenesis;GO:1901143//insulin catabolic process;GO:0016477//cell migration;GO:0001568//blood vessel development;GO:0015721//bile acid and bile salt transport;GO:0050860//negative regulation of T cell receptor signaling pathway;GO:0030853//negative regulation of granulocyte differentiation;GO:0043116//negative regulation of vascular permeability;GO:0001915//negative regulation of T cell mediated cytotoxicity;GO:1903385//regulation of homophilic cell adhesion;GO:0010594//regulation of endothelial cell migration;GO:0090331//negative regulation of platelet aggregation;GO:0001558//regulation of cell growth;GO:0038016//insulin receptor internalization;GO:0002859//negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target;GO:0001525//angiogenesis;GO:0014066//regulation of phosphatidylinositol 3-kinase signaling;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0035726//common myeloid progenitor cell proliferation;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0051055//negative regulation of lipid biosynthetic process;GO:2000346//negative regulation of hepatocyte proliferation;GO:0032692//negative regulation of interleukin-1 production;GO:0030334//regulation of cell migration;GO:0007229//integrin-mediated signaling pathway;GO:0043312//neutrophil degranulation;GO:0045601//regulation of endothelial cell differentiation;GO:0044319//wound healing, spreading of cells;GO:0038158//granulocyte colony-stimulating factor signaling pathway;GO:0043318//negative regulation of cytotoxic T cell degranulation;GO:0050900//leukocyte migration;GO:2001214//positive regulation of vasculogenesis;GO:0060312//regulation of blood vessel remodeling;GO:0032869//cellular response to insulin stimulus;GO:0006469//negative regulation of protein kinase activity;GO:0045717//negative regulation of fatty acid biosynthetic process;GO:0098742//cell-cell adhesion via plasma-membrane adhesion molecules;GO:0042058//regulation of epidermal growth factor receptor signaling pathway","K06499//carcinoembryonic antigen-related cell adhesion molecule","XP_004060901.2//PREDICTED: carcinoembryonic antigen-related cell adhesion molecule 1 isoform X2 [Gorilla gorilla gorilla];NP_001703.2//carcinoembryonic antigen-related cell adhesion molecule 1 isoform 1 precursor [Homo sapiens];NP_001171744.1//carcinoembryonic antigen-related cell adhesion molecule 1 isoform 3 precursor [Homo sapiens]","4;1//3;2//1"]
[283212,1952,0.25,0.41,0.713695814843359,0.482415676328061,"*",0.330298,"KLHL35","GO:0031463//Cul3-RING ubiquitin ligase complex","NA","GO:0016567//protein ubiquitination","K10461//kelch-like protein 24/35","XP_011543256.1//PREDICTED: kelch-like protein 35 isoform X1 [Homo sapiens]","2//1"]
[132158,3798,2.07,3.38,0.707392478782859,2.642074640625E-3,"*",0.000804498,"GLYCTK","GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005737//cytoplasm","GO:0005524//ATP binding;GO:0008887//glycerate kinase activity","GO:0061624//fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate;GO:0006468//protein phosphorylation","K11529//glycerate 2-kinase [EC:2.7.1.165]","NP_660305.2//glycerate kinase isoform 1 [Homo sapiens];XP_016861219.1//PREDICTED: glycerate kinase isoform X1 [Homo sapiens]","1//3;3//A2MP1"]
[10410,678,30.87,50.37,0.706359248043061,{"v":4.57552427671657e-09,"d":"4.58E-09"},"*",{"v":5.54826E-10,"d":"5.55E-10"},"IFITM3","GO:0005765//lysosomal membrane;GO:0070062//extracellular exosome;GO:0031902//late endosome membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","NA","GO:0035456//response to interferon-beta;GO:0060337//type I interferon signaling pathway;GO:0051607//defense response to virus;GO:0046597//negative regulation of viral entry into host cell;GO:0035455//response to interferon-alpha;GO:0045071//negative regulation of viral genome replication;GO:0034341//response to interferon-gamma;GO:0006955//immune response;GO:0032897//negative regulation of viral transcription;GO:0009615//response to virus","K06566//interferon induced transmembrane protein","XP_007984939.1//PREDICTED: interferon-induced transmembrane protein 3 [Chlorocebus sabaeus]","2//1"]
[79669,2188,2.11,3.44,0.705165565994913,0.00915840720160848,"*",0.0031367,"C3orf52","GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","NA","NA","NA","NP_001165218.1//TPA-induced transmembrane protein isoform 1 [Homo sapiens];NP_078892.2//TPA-induced transmembrane protein isoform 2 [Homo sapiens]","1//3;2//1"]
[10161,2561,0.59,0.96,0.702319451359315,0.163463190181067,"*",0.084208,"LPAR6","GO:0043231//intracellular membrane-bounded organelle;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0070915//lysophosphatidic acid receptor activity;GO:0004930//G-protein coupled receptor activity","GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway;GO:0035025//positive regulation of Rho protein signal transduction","K04273//lysophosphatidic acid receptor 6","NP_005758.2//lysophosphatidic acid receptor 6 [Homo sapiens]","1//3;5"]
[3038,3810,22.79,37.08,0.702240319360234,{"v":2.55455537762238E-41,"d":"2.55E-41"},"*",{"v":4.5737e-43,"d":"4.57E-43"},"HAS3","GO:0005887//integral component of plasma membrane;GO:0036117//hyaluranon cable;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0050501//hyaluronan synthase activity","GO:0045226//extracellular polysaccharide biosynthetic process;GO:1900106//positive regulation of hyaluranon cable assembly;GO:0007155//cell adhesion;GO:0030213//hyaluronan biosynthetic process;GO:0085029//extracellular matrix assembly;GO:0005975//carbohydrate metabolic process;GO:0045893//positive regulation of transcription, DNA-templated","K00752//hyaluronan synthase [EC:2.4.1.212]","NP_619515.1//hyaluronan synthase 3 isoform b [Homo sapiens];XP_012597862.1//hyaluronan synthase 3 isoform X3 [Microcebus murinus];NP_005320.2//hyaluronan synthase 3 isoform a [Homo sapiens]","1//3;2//1"]
[4314,1906,0.08,0.13,0.700439718141092,0.781865098436719,"*",0.685686,"MMP3","GO:0031012//extracellular matrix;GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix","GO:0004252//serine-type endopeptidase activity;GO:0004175//endopeptidase activity;GO:0008237//metallopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding","GO:0032461//positive regulation of protein oligomerization;GO:0022617//extracellular matrix disassembly;GO:0071732//cellular response to nitric oxide;GO:0006508//proteolysis;GO:1903209//positive regulation of oxidative stress-induced cell death;GO:0010727//negative regulation of hydrogen peroxide metabolic process;GO:0030574//collagen catabolic process","K01394//matrix metalloproteinase-3 (stromelysin 1, progelatinase) [EC:3.4.24.17]","NP_002413.1//stromelysin-1 preproprotein [Homo sapiens]",4]
[84898,12135,0.16,0.26,0.700439718141092,0.128381482647585,"*",0.0628968,"PLXDC2","GO:0070062//extracellular exosome;GO:0016021//integral component of membrane","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K11447//histone demethylase [EC:1.14.11.-];K01064//wingless-type MMTV integration site family, member 9","NP_001269665.1//plexin domain-containing protein 2 isoform 2 [Homo sapiens];NP_116201.7//plexin domain-containing protein 2 isoform 1 precursor [Homo sapiens]","8;1//3"]
[5787,11707,0.08,0.13,0.700439718141092,0.423727686595583,"*",0.27863,"PTPRB","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane;GO:0070821//tertiary granule membrane;GO:0005886//plasma membrane;GO:0043235//receptor complex","GO:0005001//transmembrane receptor protein tyrosine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity","GO:0001525//angiogenesis;GO:0006470//protein dephosphorylation;GO:0043312//neutrophil degranulation;GO:0016311//dephosphorylation;GO:0006796//phosphate-containing compound metabolic process","K05694//receptor-type tyrosine-protein phosphatase beta [EC:3.1.3.48]","NP_001193900.1//receptor-type tyrosine-protein phosphatase beta isoform c precursor [Homo sapiens];NP_002828.3//receptor-type tyrosine-protein phosphatase beta isoform b precursor [Homo sapiens];NP_001103224.1//receptor-type tyrosine-protein phosphatase beta isoform a [Homo sapiens];NP_001317133.1//receptor-type tyrosine-protein phosphatase beta isoform e [Homo sapiens];NP_001193901.1//receptor-type tyrosine-protein phosphatase beta isoform d precursor [Homo sapiens]","1//3;3//A2MP1;2//1;5"]
[90249,3749,0.08,0.13,0.700439718141092,0.665710391400473,"*",0.546646,"UNC5A","GO:0031226//intrinsic component of plasma membrane;GO:0045121//membrane raft;GO:0016021//integral component of membrane;GO:0032809//neuronal cell body membrane;GO:0005886//plasma membrane;GO:0032589//neuron projection membrane","NA","GO:0033564//anterior/posterior axon guidance;GO:0031175//neuron projection development;GO:0038007//netrin-activated signaling pathway;GO:0007411//axon guidance;GO:0006915//apoptotic process","K07521//netrin receptor unc-5","EDL41165.1//unc-5 homolog A (C. elegans), isoform CRA_b, partial [Mus musculus]","2//1"]
[132228,1583,2.45,3.98,0.699986681541078,0.0194671524928846,"*",0.00727916,"LSMEM2","NA","NA","NA","K09291//nucleoprotein TPR","XP_011794412.1//PREDICTED: leucine-rich single-pass membrane protein 2 isoform X2 [Colobus angolensis palliatus];XP_011794411.1//PREDICTED: leucine-rich single-pass membrane protein 2 isoform X1 [Colobus angolensis palliatus]","1//3;2//1"]
[3754,2304,8.96,14.55,0.699448515738042,{"v":3.71106502189781e-09,"d":"3.71E-09"},"*",{"v":4.45588e-10,"d":"4.46E-10"},"KCNF1","NA","NA","NA","K04899//potassium voltage-gated channel subfamily F member 1","XP_017708824.1//PREDICTED: potassium voltage-gated channel subfamily F member 1 [Rhinopithecus bieti]",4]
[140731,3412,0.82,1.33,0.697730430883106,0.0506701034696589,"*",0.0214842,"ANKRD60","NA","NA","NA","K10380//ankyrin;K01064//wingless-type MMTV integration site family, member 9","NP_001291298.1//ankyrin repeat domain-containing protein 60 [Homo sapiens]","1//3"]
[3563,1479,0.71,1.15,0.695742931439693,0.47202310076378,"*",0.321114,"IL3RA","GO:0005622//intracellular;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004713//protein tyrosine kinase activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0004912//interleukin-3 receptor activity","GO:0000165//MAPK cascade","K04737//interleukin 3 receptor alpha","BAA08393.1//interleukin 3 receptor alpha subunit, partial [Homo sapiens];NP_001254642.1//interleukin-3 receptor subunit alpha isoform 2 precursor [Homo sapiens]","1//3;3//A2MP1"]
[56063,1154,2.98,4.82,0.6937208157678,0.0322765147839749,"*",0.0128609,"TMEM234","GO:0016021//integral component of membrane","NA","NA","K03246//translation initiation factor 3 subunit I;K15683//NF-X1-type zinc finger protein NFXL1","NP_061991.3//transmembrane protein 234 precursor [Homo sapiens]",4]
[27294,1098,0.6,0.97,0.693022246578609,0.430011970448949,"*",0.284216,"DHDH","NA","GO:0009055//electron transfer activity;GO:0047115//trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity;GO:0047837//D-xylose 1-dehydrogenase (NADP+) activity;GO:0008746//NAD(P)+ transhydrogenase activity;GO:0016491//oxidoreductase activity","GO:0005975//carbohydrate metabolic process;GO:0042843//D-xylose catabolic process","K00078//dihydrodiol dehydrogenase / D-xylose 1-dehydrogenase (NADP) [EC:1.3.1.20 1.1.1.179]","XP_004061157.2//PREDICTED: trans-1,2-dihydrobenzene-1,2-diol dehydrogenase [Gorilla gorilla gorilla]","3//A2MP1"]
[8609,8375,4.4,7.11,0.692346036094756,{"v":1.48713817677419e-13,"d":"1.49E-13"},"*",{"v":1.154408E-14,"d":"1.15E-14"},"KLF7","GO:0005634//nucleus","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003713//transcription coactivator activity;GO:0008270//zinc ion binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007411//axon guidance;GO:0048813//dendrite morphogenesis","K09228//KRAB domain-containing zinc finger protein;K09207//krueppel-like factor 6/7","XP_003363357.2//PREDICTED: Krueppel-like factor 7 [Equus caballus];NP_001257871.1//Krueppel-like factor 7 isoform 2 [Homo sapiens];XP_011510376.1//PREDICTED: Krueppel-like factor 7 isoform X5 [Homo sapiens];XP_008972505.1//PREDICTED: Krueppel-like factor 7 isoform X3 [Pan paniscus]","1//3;3//A2MP1"]
[91543,3512,0.13,0.21,0.691877704637668,0.447513668658946,"*",0.299986,"RSAD2","GO:0005783//endoplasmic reticulum;GO:0005741//mitochondrial outer membrane;GO:0005794//Golgi apparatus;GO:0005811//lipid droplet;GO:0001650//fibrillar center;GO:0005743//mitochondrial inner membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005739//mitochondrion","GO:0046872//metal ion binding;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0043621//protein self-association;GO:0003824//catalytic activity;GO:0051536//iron-sulfur cluster binding","GO:0060337//type I interferon signaling pathway;GO:0050709//negative regulation of protein secretion;GO:2000553//positive regulation of T-helper 2 cell cytokine production;GO:0051607//defense response to virus;GO:0016032//viral process;GO:0034157//positive regulation of toll-like receptor 7 signaling pathway;GO:0043367//CD4-positive, alpha-beta T cell differentiation;GO:0034165//positive regulation of toll-like receptor 9 signaling pathway;GO:0045071//negative regulation of viral genome replication;GO:0035710//CD4-positive, alpha-beta T cell activation;GO:0009615//response to virus","K15045//radical S-adenosyl methionine domain-containing protein 2","NP_542388.2//radical S-adenosyl methionine domain-containing protein 2 [Homo sapiens]",4]
[80008,1961,14.46,23.35,0.691354997645906,{"v":5.15351396735273e-12,"d":"5.15E-12"},"*",{"v":4.5457E-13,"d":"4.55E-13"},"TMEM156","GO:0016021//integral component of membrane","NA","NA","K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K01064//wingless-type MMTV integration site family, member 9;K12025//tripartite motif-containing protein 52","NP_079219.1//transmembrane protein 156 isoform 1 [Homo sapiens];NP_001290157.1//transmembrane protein 156 isoform 2 [Homo sapiens]","1//3;2//1"]
[4234,1294,22.17,35.78,0.690544617184601,{"v":3.8199242519685e-11,"d":"3.82E-11"},"*",{"v":3.6444e-12,"d":"3.64E-12"},"METTL1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol","GO:0000049//tRNA binding;GO:0008176//tRNA (guanine-N7-)-methyltransferase activity","NA","K03439//tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]","EAW97066.1//hCG2044065 [Homo sapiens];EAW97070.1//hCG2014568, isoform CRA_c [Homo sapiens]","3//A2MP1;5"]
[26229,1714,38.08,61.39,0.688970191194394,{"v":8.92623721276596e-25,"d":"8.93E-25"},"*",{"v":3.15162e-26,"d":"3.15E-26"},"B3GAT3","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005801//cis-Golgi network;GO:0000139//Golgi membrane","GO:0046872//metal ion binding;GO:0015018//galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity;GO:0015020//glucuronosyltransferase activity;GO:0072542//protein phosphatase activator activity","GO:0006486//protein glycosylation;GO:0090316//positive regulation of intracellular protein transport;GO:0006024//glycosaminoglycan biosynthetic process;GO:0005975//carbohydrate metabolic process;GO:0050650//chondroitin sulfate proteoglycan biosynthetic process;GO:0015012//heparan sulfate proteoglycan biosynthetic process;GO:0050651//dermatan sulfate proteoglycan biosynthetic process;GO:0030204//chondroitin sulfate metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0043085//positive regulation of catalytic activity","K10158//galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 [EC:2.4.1.135]","NP_036332.2//galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 isoform 1 [Homo sapiens];NP_001275651.1//galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 isoform 3 [Homo sapiens];XP_007993671.1//PREDICTED: galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 isoform X3 [Chlorocebus sabaeus];XP_016801977.1//PREDICTED: galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 isoform X1 [Pan troglodytes]","1//3;3//A2MP1"]
[8613,3324,7.32,11.79,0.68764816469572,{"v":2.4710284028777e-10,"d":"2.47E-10"},"*",{"v":2.58024E-11,"d":"2.58E-11"},"PLPP3","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005887//integral component of plasma membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005912//adherens junction","GO:0042577//lipid phosphatase activity;GO:0005178//integrin binding;GO:0004721//phosphoprotein phosphatase activity;GO:0042392//sphingosine-1-phosphate phosphatase activity;GO:0008195//phosphatidate phosphatase activity","GO:1902068//regulation of sphingolipid mediated signaling pathway;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0001568//blood vessel development;GO:0008354//germ cell migration;GO:0098609//cell-cell adhesion;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0046839//phospholipid dephosphorylation;GO:0044329//canonical Wnt signaling pathway involved in positive regulation of cell-cell adhesion;GO:0060020//Bergmann glial cell differentiation;GO:0034109//homotypic cell-cell adhesion;GO:0044328//canonical Wnt signaling pathway involved in positive regulation of endothelial cell migration;GO:0001702//gastrulation with mouth forming second;GO:0030148//sphingolipid biosynthetic process;GO:0030111//regulation of Wnt signaling pathway;GO:0060070//canonical Wnt signaling pathway;GO:0001933//negative regulation of protein phosphorylation;GO:0044330//canonical Wnt signaling pathway involved in positive regulation of wound healing;GO:0006644//phospholipid metabolic process;GO:0050821//protein stabilization;GO:0006629//lipid metabolic process","K01080//phosphatidate phosphatase [EC:3.1.3.4]","NP_003704.3//phospholipid phosphatase 3 [Homo sapiens]",4]
[3142,2308,3.92,6.31,0.686786350867341,0.0002139300099106,"*",{"v":5.24312E-5,"d":"5.24E-05"},"HLX","GO:0005634//nucleus","GO:0043565//sequence-specific DNA binding","GO:0001889//liver development;GO:0030154//cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0045627//positive regulation of T-helper 1 cell differentiation;GO:0006351//transcription, DNA-templated;GO:0045629//negative regulation of T-helper 2 cell differentiation;GO:0048484//enteric nervous system development;GO:0046622//positive regulation of organ growth;GO:0007275//multicellular organism development;GO:0007519//skeletal muscle tissue development;GO:0048557//embryonic digestive tract morphogenesis;GO:0008284//positive regulation of cell proliferation","K09339//homeobox protein HLX1","NP_068777.1//H2.0-like homeobox protein [Homo sapiens]","3//A2MP1"]
[10693,1773,0.23,0.37,0.685891409571937,0.578636030571061,"*",0.421824,"CCT6B","GO:0005829//cytosol;GO:0005832//chaperonin-containing T-complex","GO:0005524//ATP binding;GO:0051082//unfolded protein binding;GO:0008565//protein transporter activity;GO:0044183//protein binding involved in protein folding","GO:0006457//protein folding;GO:0051131//chaperone-mediated protein complex assembly;GO:0006458//'de novo' protein folding;GO:1901998//toxin transport;GO:0007283//spermatogenesis;GO:0061077//chaperone-mediated protein folding","K09498//T-complex protein 1 subunit zeta","NP_001180458.1//T-complex protein 1 subunit zeta-2 isoform 2 [Homo sapiens];NP_001180459.1//T-complex protein 1 subunit zeta-2 isoform 3 [Homo sapiens];NP_006575.2//T-complex protein 1 subunit zeta-2 isoform 1 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[140606,741,29.43,47.3,0.684552641286363,{"v":7.6983624774323e-09,"d":"7.70E-09"},"*",{"v":9.6097e-10,"d":"9.61E-10"},"SELENOM","GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0048471//perinuclear region of cytoplasm","NA","GO:0042445//hormone metabolic process;GO:0035934//corticosterone secretion;GO:0010269//response to selenium ion;GO:0060612//adipose tissue development;GO:0035264//multicellular organism growth","NA","NP_536355.1//selenoprotein M precursor [Homo sapiens]","3//A2MP1"]
[55601,6099,0.28,0.45,0.68449817427207,0.204228158701996,"*",0.1095294,"DDX60","GO:0045111//intermediate filament cytoskeleton;GO:0005829//cytosol","GO:0005524//ATP binding;GO:0003725//double-stranded RNA binding;GO:0003690//double-stranded DNA binding;GO:0003727//single-stranded RNA binding","GO:1900245//positive regulation of MDA-5 signaling pathway;GO:1900246//positive regulation of RIG-I signaling pathway;GO:0051607//defense response to virus","K20103//ATP-dependent RNA helicase DDX60 [EC:3.6.4.13]","XP_003899396.1//probable ATP-dependent RNA helicase DDX60 isoform X2 [Papio anubis]",5]
[22798,2652,0.89,1.43,0.684137905811992,0.0850588049491339,"*",0.0387328,"LAMB4","GO:0005604//basement membrane","NA","GO:0007155//cell adhesion","K06245//laminin, beta 4","NP_001304976.1//laminin subunit beta-4 isoform 2 precursor [Homo sapiens];NP_001304977.1//laminin subunit beta-4 isoform 3 precursor [Homo sapiens];XP_008961826.1//PREDICTED: LOW QUALITY PROTEIN: laminin subunit beta-4 [Pan paniscus]","1//3;2//1"]
[8701,13896,0.66,1.06,0.683526335204746,0.000166874665278501,"*",{"v":4.0136e-05,"d":"4.01E-05"},"DNAH11","GO:0005874//microtubule;GO:0030286//dynein complex;GO:0031514//motile cilium;GO:0005737//cytoplasm;GO:0005930//axoneme","GO:0051959//dynein light intermediate chain binding;GO:0045505//dynein intermediate chain binding;GO:0005524//ATP binding;GO:0003777//microtubule motor activity;GO:0045503//dynein light chain binding;GO:0008569//ATP-dependent microtubule motor activity, minus-end-directed","GO:0003341//cilium movement;GO:0007018//microtubule-based movement;GO:0030317//flagellated sperm motility;GO:0007368//determination of left/right symmetry;GO:0007507//heart development;GO:0003356//regulation of cilium beat frequency","K10408//dynein heavy chain, axonemal","NP_001264044.1//dynein heavy chain 11, axonemal [Homo sapiens]","1//3"]
[146822,667,0.71,1.14,0.68314289466006,0.482459788953914,"*",0.330298,"CDRT15","GO:0016021//integral component of membrane","NA","NA","NA","AAI46860.1//CMT1A duplicated region transcript 15 [Homo sapiens];NP_001335710.1//CMT1A duplicated region transcript 15 protein isoform 2 [Homo sapiens]","1//3;2//1"]
[122509,708,5.42,8.7,0.682722549382219,0.0325425014559147,"*",0.01298522,"IFI27L1","GO:0016021//integral component of membrane","NA","NA","NA","EAW81553.1//family with sequence similarity 14, member B, isoform CRA_a, partial [Homo sapiens];XP_016876450.1//PREDICTED: interferon alpha-inducible protein 27-like protein 1 isoform X2 [Homo sapiens]","2//1"]
[6253,1669,5.33,8.55,0.681788887014084,0.0191598556311819,"*",0.00715466,"RTN2","GO:0030315//T-tubule;GO:0005783//endoplasmic reticulum;GO:0014802//terminal cisterna;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","NA","GO:0065002//intracellular protein transmembrane transport;GO:0046324//regulation of glucose import","K20722//reticulon-2","NP_005610.1//reticulon-2 isoform A [Homo sapiens];NP_996783.1//reticulon-2 isoform B [Homo sapiens]","4;2//1"]
[84261,1750,5.11,8.19,0.680540160703387,0.000288894722211155,"*",{"v":7.26306e-05,"d":"7.26E-05"},"FBXW9","GO:0005829//cytosol","GO:0004842//ubiquitin-protein transferase activity","GO:0043687//post-translational protein modification;GO:0000209//protein polyubiquitination","K10265//F-box and WD-40 domain protein 9","NP_115677.2//F-box/WD repeat-containing protein 9 [Homo sapiens]","2//1"]
[4489,468,9.06,14.51,0.679464564020509,0.023978447962178,"*",0.0092077,"MT1A","NA","NA","NA","K14739//metallothionein 1/2","XP_009194736.1//metallothionein-1E isoform X2 [Papio anubis]","2//1"]
[81844,4723,6.9,11.05,0.679378102613262,{"v":2.65835031496063e-13,"d":"2.66E-13"},"*",{"v":2.1135E-14,"d":"2.11E-14"},"TRIM56","GO:0005829//cytosol;GO:0005622//intracellular;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0008270//zinc ion binding;GO:0004842//ubiquitin-protein transferase activity","GO:0070534//protein K63-linked ubiquitination;GO:0034340//response to type I interferon;GO:0032479//regulation of type I interferon production;GO:0032608//interferon-beta production;GO:0051607//defense response to virus","K12026//tripartite motif-containing protein 56 [EC:2.3.2.27]","NP_112223.1//E3 ubiquitin-protein ligase TRIM56 [Homo sapiens]","2//1"]
[3691,5783,16.23,25.99,0.679293633924229,{"v":2.57622811715976E-36,"d":"2.58E-36"},"*",{"v":5.45114e-38,"d":"5.45E-38"},"ITGB4","GO:0008305//integrin complex;GO:0070062//extracellular exosome;GO:0031252//cell leading edge;GO:0005634//nucleus;GO:0009986//cell surface;GO:0030056//hemidesmosome;GO:0030054//cell junction;GO:0005886//plasma membrane;GO:0043235//receptor complex","GO:0001664//G-protein coupled receptor binding;GO:0004872//receptor activity","GO:0009611//response to wounding;GO:0043588//skin development;GO:0031581//hemidesmosome assembly;GO:0048565//digestive tract development;GO:0097186//amelogenesis;GO:0007160//cell-matrix adhesion;GO:0007155//cell adhesion;GO:0072001//renal system development;GO:0035878//nail development;GO:0048870//cell motility;GO:0030198//extracellular matrix organization;GO:0007229//integrin-mediated signaling pathway;GO:0006914//autophagy;GO:0048333//mesodermal cell differentiation","K06525//integrin beta 4","XP_006721931.1//PREDICTED: integrin beta-4 isoform X4 [Homo sapiens];XP_006721930.1//PREDICTED: integrin beta-4 isoform X3 [Homo sapiens];XP_006721933.1//PREDICTED: integrin beta-4 isoform X6 [Homo sapiens]","4;1//3;2//1"]
[9149,2510,20.47,32.76,0.678424254617598,{"v":3.2570829007371e-19,"d":"3.26E-19"},"*",{"v":1.659738e-20,"d":"1.66E-20"},"DYRK1B","NA","NA","NA","K08825//dual specificity tyrosine-phosphorylation-regulated kinase 1 [EC:2.7.12.1]","XP_018871474.1//PREDICTED: dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform X2 [Gorilla gorilla gorilla];XP_018871473.1//PREDICTED: dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform X1 [Gorilla gorilla gorilla];XP_512657.3//PREDICTED: dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform X1 [Pan troglodytes]","2//1"]
[81793,3501,0.7,1.12,0.678071905112638,0.121375486832556,"*",0.0586286,"TLR10","GO:0016020//membrane;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004888//transmembrane signaling receptor activity","GO:0050729//positive regulation of inflammatory response;GO:0002224//toll-like receptor signaling pathway;GO:0006954//inflammatory response;GO:0050707//regulation of cytokine secretion;GO:0006955//immune response;GO:0034166//toll-like receptor 10 signaling pathway;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0045087//innate immune response","K10171//toll-like receptor 10","NP_112218.2//toll-like receptor 10 isoform a [Homo sapiens]","1//3;3//A2MP1;2//1"]
[5199,1669,0.15,0.24,0.678071905112638,0.628851793012217,"*",0.505908,"CFP","GO:0031012//extracellular matrix;GO:1904724//tertiary granule lumen;GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0035580//specific granule lumen;GO:0005576//extracellular region","NA","GO:0030449//regulation of complement activation;GO:0006956//complement activation;GO:0043312//neutrophil degranulation;GO:0006955//immune response;GO:0036066//protein O-linked fucosylation;GO:0042742//defense response to bacterium;GO:0006957//complement activation, alternative pathway","K15412//complement factor properdin","NP_002612.1//properdin precursor [Homo sapiens]","1//3;2//1"]
[4094,6887,0.05,0.08,0.678071905112638,0.540251097826087,"*",0.385826,"MAF","GO:0005634//nucleus;GO:0000785//chromatin;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0070306//lens fiber cell differentiation;GO:0032330//regulation of chondrocyte differentiation;GO:0048839//inner ear development;GO:0006351//transcription, DNA-templated;GO:0001816//cytokine production;GO:0048468//cell development;GO:0006366//transcription from RNA polymerase II promoter","K09035//transcription factor Maf","XP_016878722.1//PREDICTED: transcription factor Maf isoform X1 [Homo sapiens];NP_005351.2//transcription factor Maf isoform a [Homo sapiens]","4;2//1"]
[84530,8494,0.1,0.16,0.678071905112638,0.309472689278917,"*",0.1832348,"SRRM4","GO:0005634//nucleus","GO:0003729//mRNA binding","GO:0043484//regulation of RNA splicing;GO:0007399//nervous system development;GO:0006397//mRNA processing;GO:0030154//cell differentiation;GO:0007605//sensory perception of sound;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0008380//RNA splicing","K13172//serine/arginine repetitive matrix protein 2","NP_919262.2//serine/arginine repetitive matrix protein 4 [Homo sapiens]","3//A2MP1"]
[57644,6602,0.05,0.08,0.678071905112638,0.540061735366281,"*",0.385826,"MYH7B","GO:0016459//myosin complex;GO:0097512//cardiac myofibril","GO:0051015//actin filament binding;GO:0005524//ATP binding;GO:0003774//motor activity","NA","K10352//myosin heavy chain","XP_022350077.1//myosin-7B [Enhydra lutris kenyoni]",4]
[57549,4029,0.1,0.16,0.678071905112638,0.57883485748647,"*",0.421824,"IGSF9","NA","NA","NA","K17341//hemicentin","AAH30141.1//Immunoglobulin superfamily, member 9 [Homo sapiens];EHH50426.1//hypothetical protein EGM_01256 [Macaca fascicularis]","1//3;3//A2MP1"]
[7294,2914,0.05,0.08,0.678071905112638,0.781195932101847,"*",0.685686,"TXK","GO:0005634//nucleus;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0005737//cytoplasm","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005524//ATP binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0001012//RNA polymerase II regulatory region DNA binding","GO:0038083//peptidyl-tyrosine autophosphorylation;GO:0042127//regulation of cell proliferation;GO:0060335//positive regulation of interferon-gamma-mediated signaling pathway;GO:0042246//tissue regeneration;GO:0010543//regulation of platelet activation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007229//integrin-mediated signaling pathway;GO:0045087//innate immune response;GO:0032729//positive regulation of interferon-gamma production;GO:0030154//cell differentiation;GO:0050852//T cell receptor signaling pathway;GO:0006468//protein phosphorylation;GO:0001816//cytokine production;GO:0002250//adaptive immune response;GO:0046777//protein autophosphorylation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007202//activation of phospholipase C activity","K08016//tyrosine-protein kinase TXK [EC:2.7.10.2]","NP_003319.2//tyrosine-protein kinase TXK [Homo sapiens]","2//1"]
[283849,2505,0.1,0.16,0.678071905112638,0.628753940091807,"*",0.505908,"EXOC3L1","GO:0030141//secretory granule;GO:0000145//exocyst;GO:0030133//transport vesicle","GO:0000149//SNARE binding","GO:0030072//peptide hormone secretion;GO:0051601//exocyst localization;GO:0006887//exocytosis","K19987//exocyst complex component 3-like protein","NP_848611.2//exocyst complex component 3-like protein [Homo sapiens]","3//A2MP1"]
[58472,1810,34.79,55.54,0.674854498198956,{"v":2.93792286666667e-24,"d":"2.94E-24"},"*",{"v":1.081444e-25,"d":"1.08E-25"},"SQOR","GO:0005743//mitochondrial inner membrane","GO:0070224//sulfide:quinone oxidoreductase activity;GO:0048038//quinone binding;GO:0016491//oxidoreductase activity","GO:0070221//sulfide oxidation, using sulfide:quinone oxidoreductase;GO:0070813//hydrogen sulfide metabolic process","K17218//sulfide:quinone oxidoreductase [EC:1.8.5.4]","NP_067022.1//sulfide:quinone oxidoreductase, mitochondrial [Homo sapiens]","1//3;3//A2MP1"]
[1316,4643,13.1,20.91,0.674626250164767,{"v":2.5732418130137e-24,"d":"2.57E-24"},"*",{"v":9.40762e-26,"d":"9.41E-26"},"KLF6","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0001650//fibrillar center","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003676//nucleic acid binding","GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0030183//B cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated","K09207//krueppel-like factor 6/7","NP_001153597.1//Krueppel-like factor 6 isoform C [Homo sapiens];NP_001153596.1//Krueppel-like factor 6 isoform B [Homo sapiens];AAC23699.1//DNA-binding protein CPBP, partial [Homo sapiens]","1//3;5"]
[339456,987,0.42,0.67,0.673771767679012,0.578437340200876,"*",0.421824,"TMEM52","GO:0016021//integral component of membrane","NA","NA","NA","NP_848640.1//transmembrane protein 52 precursor [Homo sapiens]","3//A2MP1"]
[929,1540,2.21,3.52,0.671529059245866,0.0340524289878543,"*",0.01369004,"CD14","GO:0070062//extracellular exosome;GO:0010008//endosome membrane;GO:0030667//secretory granule membrane;GO:0005615//extracellular space;GO:0031362//anchored component of external side of plasma membrane;GO:0046696//lipopolysaccharide receptor complex;GO:0045121//membrane raft;GO:0005794//Golgi apparatus;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0001530//lipopolysaccharide binding;GO:0071723//lipopeptide binding;GO:0001847//opsonin receptor activity;GO:0070891//lipoteichoic acid binding;GO:0016019//peptidoglycan receptor activity","GO:0032481//positive regulation of type I interferon production;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0097190//apoptotic signaling pathway;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0032026//response to magnesium ion;GO:0071222//cellular response to lipopolysaccharide;GO:0007166//cell surface receptor signaling pathway;GO:0045807//positive regulation of endocytosis;GO:0045471//response to ethanol;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0032760//positive regulation of tumor necrosis factor production;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0045087//innate immune response;GO:0032729//positive regulation of interferon-gamma production;GO:0006909//phagocytosis;GO:0009408//response to heat;GO:0006915//apoptotic process;GO:0071726//cellular response to diacyl bacterial lipopeptide;GO:0034612//response to tumor necrosis factor;GO:0006898//receptor-mediated endocytosis;GO:0051602//response to electrical stimulus;GO:0043312//neutrophil degranulation;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0034142//toll-like receptor 4 signaling pathway;GO:0071727//cellular response to triacyl bacterial lipopeptide;GO:0071223//cellular response to lipoteichoic acid;GO:0002224//toll-like receptor signaling pathway;GO:0034128//negative regulation of MyD88-independent toll-like receptor signaling pathway;GO:0006954//inflammatory response;GO:0071219//cellular response to molecule of bacterial origin;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:2000484//positive regulation of interleukin-8 secretion;GO:0070266//necroptotic process;GO:0002755//MyD88-dependent toll-like receptor signaling pathway","K04391//monocyte differentiation antigen CD14","NP_000582.1//monocyte differentiation antigen CD14 precursor [Homo sapiens]","1//3;3//A2MP1;2//1"]
[5720,1033,50.84,80.97,0.671423447183049,{"v":1.00692348392371E-20,"d":"1.01E-20"},"*",{"v":4.62678e-22,"d":"4.63E-22"},"PSME1","NA","NA","NA","K06696//proteasome activator subunit 1 (PA28 alpha)","XP_509864.3//PREDICTED: proteasome activator complex subunit 1 isoform X2 [Pan troglodytes];XP_009425837.1//PREDICTED: proteasome activator complex subunit 1 isoform X1 [Pan troglodytes]","1//3;3//A2MP1;2//1"]
[286183,1854,0.22,0.35,0.669851398307669,0.578785137948806,"*",0.421824,"NKAIN3","GO:0016021//integral component of membrane","NA","NA","NA","NP_001291462.1//sodium/potassium-transporting ATPase subunit beta-1-interacting protein 3 precursor [Homo sapiens]","1//3"]
[10417,1825,0.22,0.35,0.669851398307669,0.578536668326608,"*",0.421824,"SPON2","GO:0070062//extracellular exosome;GO:0005578//proteinaceous extracellular matrix","GO:0046872//metal ion binding;GO:0001530//lipopolysaccharide binding;GO:0003823//antigen binding","GO:0050832//defense response to fungus;GO:0032755//positive regulation of interleukin-6 production;GO:0051607//defense response to virus;GO:0071222//cellular response to lipopolysaccharide;GO:0002448//mast cell mediated immunity;GO:0032760//positive regulation of tumor necrosis factor production;GO:0007155//cell adhesion;GO:0060907//positive regulation of macrophage cytokine production;GO:0043152//induction of bacterial agglutination;GO:0007411//axon guidance;GO:0045087//innate immune response;GO:0008228//opsonization","K22020//mucin-19;K06532//prominin 1","XP_004091742.1//PREDICTED: LOW QUALITY PROTEIN: spondin-2 [Nomascus leucogenys]","1//3;3//A2MP1;2//1"]
[4008,7018,4.74,7.54,0.669677464370405,{"v":1.16341351875E-12,"d":"1.16E-12"},"*",{"v":9.78858e-14,"d":"9.79E-14"},"LMO7","GO:0005634//nucleus;GO:0005925//focal adhesion;GO:0000151//ubiquitin ligase complex;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0004842//ubiquitin-protein transferase activity","GO:0043687//post-translational protein modification;GO:0016567//protein ubiquitination;GO:0030155//regulation of cell adhesion;GO:0023051//regulation of signaling;GO:0000209//protein polyubiquitination","K06084//F-box protein 20","XP_016780876.1//PREDICTED: LIM domain only protein 7 isoform X11 [Pan troglodytes];NP_005349.3//LIM domain only protein 7 isoform 1 [Homo sapiens];Q8WWI1.3//RecName: Full=LIM domain only protein 7; Short=LMO-7; AltName: Full=F-box only protein 20; AltName: Full=LOMP;ACV60543.1//LIM domain only 7 protein [Homo sapiens]","1//3;2//1;5"]
[54704,4254,2.51,3.99,0.668701382271574,0.000110152460367171,"*",{"v":2.55418E-5,"d":"2.55E-05"},"PDP1","NA","NA","NA","K01102//pyruvate dehydrogenase phosphatase [EC:3.1.3.43]","AAH64978.1//PPM2C protein, partial [Homo sapiens];XP_003311895.1//PREDICTED: pyruvate dehyrogenase phosphatase catalytic subunit 1 isoform X2 [Pan troglodytes];XP_019780696.1//PREDICTED: pyruvate dehyrogenase phosphatase catalytic subunit 1 isoform X1 [Tursiops truncatus];XP_016869077.1//PREDICTED: pyruvate dehyrogenase phosphatase catalytic subunit 1 isoform X2 [Homo sapiens]","1//3;3//A2MP1"]
[56246,673,1.9,3.02,0.668549130994131,0.213878768373598,"*",0.1158298,"MRAP","GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane","GO:0031783//type 5 melanocortin receptor binding;GO:0031780//corticotropin hormone receptor binding;GO:0031782//type 4 melanocortin receptor binding;GO:0042802//identical protein binding;GO:0070996//type 1 melanocortin receptor binding;GO:0031781//type 3 melanocortin receptor binding","GO:0050873//brown fat cell differentiation;GO:0030819//positive regulation of cAMP biosynthetic process;GO:0034394//protein localization to cell surface","NA","EAX09880.1//melanocortin 2 receptor accessory protein, isoform CRA_c, partial [Homo sapiens];NP_848932.1//melanocortin-2 receptor accessory protein isoform alpha [Homo sapiens];NP_996781.1//melanocortin-2 receptor accessory protein isoform beta [Homo sapiens]","1//3;3//A2MP1"]
[3566,3627,9.86,15.65,0.666503105442069,{"v":2.67868018568057e-13,"d":"2.68E-13"},"*",{"v":2.13134E-14,"d":"2.13E-14"},"IL4R","NA","NA","NA","K05071//interleukin 4 receptor","XP_009428807.2//PREDICTED: interleukin-4 receptor subunit alpha isoform X1 [Pan troglodytes];XP_510892.4//PREDICTED: interleukin-4 receptor subunit alpha isoform X2 [Pan troglodytes];XP_011544130.1//PREDICTED: interleukin-4 receptor subunit alpha isoform X2 [Homo sapiens]","1//3;3//A2MP1"]
[432,1402,0.29,0.46,0.665580960929441,0.578586345182895,"*",0.421824,"ASGR1","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0004873//asialoglycoprotein receptor activity;GO:0046872//metal ion binding;GO:0030246//carbohydrate binding;GO:0042803//protein homodimerization activity","GO:0018279//protein N-linked glycosylation via asparagine;GO:0006898//receptor-mediated endocytosis;GO:0006897//endocytosis;GO:0031668//cellular response to extracellular stimulus","K10063//asialoglycoprotein receptor 1","NP_001184145.1//asialoglycoprotein receptor 1 isoform b [Homo sapiens];NP_001662.1//asialoglycoprotein receptor 1 isoform a [Homo sapiens]","4;2//1"]
[4335,4865,13.01,20.63,0.665122859168689,{"v":8.34858365562914e-24,"d":"8.35E-24"},"*",{"v":3.15672e-25,"d":"3.16E-25"},"MNT","GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0003714//transcription corepressor activity;GO:0003713//transcription coactivator activity;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA binding transcription factor activity;GO:0001227//transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0046983//protein dimerization activity","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007275//multicellular organism development;GO:0007569//cell aging;GO:0051726//regulation of cell cycle;GO:0006366//transcription from RNA polymerase II promoter;GO:0008285//negative regulation of cell proliferation;GO:2001234//negative regulation of apoptotic signaling pathway","K09115//MAX-binding protein","NP_064706.1//max-binding protein MNT [Homo sapiens]","2//1"]
[79929,2154,1.64,2.6,0.664815808410371,0.0358803576274328,"*",0.01454172,"MAP6D1","GO:0005874//microtubule;GO:0005798//Golgi-associated vesicle;GO:0005801//cis-Golgi network","GO:0005516//calmodulin binding;GO:0008017//microtubule binding","GO:0000226//microtubule cytoskeleton organization;GO:0018009//N-terminal peptidyl-L-cysteine N-palmitoylation;GO:0007026//negative regulation of microtubule depolymerization;GO:0032418//lysosome localization;GO:0048813//dendrite morphogenesis","K10432//microtubule-associated protein 6;K09650//rhomboid-like protein [EC:3.4.21.105]","NP_079147.1//MAP6 domain-containing protein 1 [Homo sapiens]","2//1"]
[23464,1606,2.17,3.44,0.664713522257619,0.0417410064781491,"*",0.01728016,"GCAT","GO:0005654//nucleoplasm;GO:0016607//nuclear speck;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0030170//pyridoxal phosphate binding;GO:0008890//glycine C-acetyltransferase activity;GO:0016874//ligase activity","GO:0009058//biosynthetic process;GO:0006520//cellular amino acid metabolic process;GO:0006567//threonine catabolic process;GO:0019518//L-threonine catabolic process to glycine","K00639//glycine C-acetyltransferase [EC:2.3.1.29]","NP_001165161.1//2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial isoform 1 precursor [Homo sapiens];NP_055106.1//2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial isoform 2 precursor [Homo sapiens]","1//3;3//A2MP1"]
[1827,2131,2.57,4.07,0.663260435072369,0.0219307391255568,"*",0.00832116,"RCAN1","GO:0005634//nucleus;GO:0005622//intracellular;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0042802//identical protein binding;GO:0008597//calcium-dependent protein serine/threonine phosphatase regulator activity;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0009612//response to mechanical stimulus;GO:0007165//signal transduction;GO:0051151//negative regulation of smooth muscle cell differentiation;GO:0043627//response to estrogen;GO:0007417//central nervous system development;GO:0008015//blood circulation;GO:0033173//calcineurin-NFAT signaling cascade;GO:0007519//skeletal muscle tissue development;GO:0070884//regulation of calcineurin-NFAT signaling cascade","K17901//calcipressin-1","NP_001272318.1//calcipressin-1 isoform d [Homo sapiens];XP_020018408.1//calcipressin-1 isoform X1 [Castor canadensis];NP_001272320.2//calcipressin-1 isoform e [Homo sapiens];EHH16988.1//Regulator of calcineurin 1, partial [Macaca mulatta];NP_004405.3//calcipressin-1 isoform a [Homo sapiens];NP_981963.1//calcipressin-1 isoform c [Homo sapiens];XP_003263947.1//PREDICTED: calcipressin-1 isoform X3 [Nomascus leucogenys];NP_001317945.1//calcipressin-1 isoform f [Homo sapiens]","6;1//3;2//1"]
[51555,8635,0.12,0.19,0.662965012722429,0.366817782178218,"*",0.227292,"PEX5L","GO:0005829//cytosol;GO:0043235//receptor complex;GO:0005778//peroxisomal membrane","GO:0031267//small GTPase binding;GO:0005052//peroxisome matrix targeting signal-1 binding;GO:0000268//peroxisome targeting sequence binding","GO:0043949//regulation of cAMP-mediated signaling;GO:0016560//protein import into peroxisome matrix, docking","K13342//peroxin-5","XP_018879929.1//PREDICTED: PEX5-related protein isoform X7 [Gorilla gorilla gorilla];NP_001243681.1//PEX5-related protein isoform 4 [Homo sapiens];NP_001336327.1//PEX5-related protein isoform 18 [Homo sapiens];NP_001243679.1//PEX5-related protein isoform 2 [Homo sapiens];XP_021790337.1//PEX5-related protein isoform X15 [Papio anubis];NP_001336325.1//PEX5-related protein isoform 16 [Homo sapiens];NP_001336319.1//PEX5-related protein isoform 12 [Homo sapiens];NP_001336322.1//PEX5-related protein isoform 14 [Homo sapiens];NP_001243682.1//PEX5-related protein isoform 5 [Homo sapiens];NP_001336318.1//PEX5-related protein isoform 11 [Homo sapiens];NP_001336315.1//PEX5-related protein isoform 9 [Homo sapiens];XP_018879928.1//PREDICTED: PEX5-related protein isoform X1 [Gorilla gorilla gorilla];NP_001336320.1//PEX5-related protein isoform 13 [Homo sapiens];BAH12041.1//unnamed protein product [Homo sapiens];NP_001336326.1//PEX5-related protein isoform 17 [Homo sapiens];NP_057643.1//PEX5-related protein isoform 1 [Homo sapiens];NP_001243680.1//PEX5-related protein isoform 3 [Homo sapiens]","1//3;2//1"]
[89765,1331,0.12,0.19,0.662965012722429,0.781641915649754,"*",0.685686,"RSPH1","GO:0005634//nucleus;GO:0072687//meiotic spindle;GO:0031514//motile cilium;GO:0005829//cytosol;GO:0000794//condensed nuclear chromosome;GO:0001520//outer dense fiber","NA","GO:0051321//meiotic cell cycle;GO:0035082//axoneme assembly;GO:0007286//spermatid development","K19755//radial spoke head protein 1","NP_543136.1//radial spoke head 1 homolog isoform 1 [Homo sapiens];NP_001273435.1//radial spoke head 1 homolog isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[55040,3944,0.24,0.38,0.662965012722429,0.350501208929123,"*",0.213298,"EPN3","GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0030136//clathrin-coated vesicle;GO:0048471//perinuclear region of cytoplasm;GO:0019897//extrinsic component of plasma membrane;GO:0005905//clathrin-coated pit","GO:0008289//lipid binding;GO:1990175//EH domain binding","NA","K12471//epsin","NP_060427.2//epsin-3 [Homo sapiens]","2//1"]
[206412,1304,0.12,0.19,0.662965012722429,0.781140219940094,"*",0.685686,"C6orf163","NA","NA","NA","K18730//PERQ amino acid-rich with GYF domain-containing protein;K20283//golgin subfamily A member 4","NP_001010868.2//uncharacterized protein C6orf163 [Homo sapiens]","2//1"]
[2170,1309,0.12,0.19,0.662965012722429,0.780416684289277,"*",0.685686,"FABP3","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0016528//sarcoplasm;GO:0005829//cytosol","GO:0008289//lipid binding;GO:0036041//long-chain fatty acid binding;GO:0008092//cytoskeletal protein binding;GO:0070538//oleic acid binding;GO:0005324//long-chain fatty acid transporter activity;GO:0005215//transporter activity;GO:0050543//icosatetraenoic acid binding","GO:0019433//triglyceride catabolic process;GO:2001245//regulation of phosphatidylcholine biosynthetic process;GO:0055091//phospholipid homeostasis;GO:0042493//response to drug;GO:0032868//response to insulin;GO:0071073//positive regulation of phospholipid biosynthetic process;GO:0046320//regulation of fatty acid oxidation;GO:0006631//fatty acid metabolic process;GO:0042632//cholesterol homeostasis;GO:0070542//response to fatty acid;GO:0044539//long-chain fatty acid import;GO:0008285//negative regulation of cell proliferation","K08752//fatty acid-binding protein 3, muscle and heart","NP_001307925.1//fatty acid-binding protein, heart isoform 1 [Homo sapiens];NP_004093.1//fatty acid-binding protein, heart isoform 2 [Homo sapiens]","1//3;4"]
[79095,723,59.15,93.64,0.662746765884862,{"v":2.20867665901943e-15,"d":"2.21E-15"},"*",{"v":1.494666e-16,"d":"1.49E-16"},"C9orf16","NA","NA","NA","K07603//collagen, type XVII, alpha;K14283//transforming acidic coiled-coil-containing protein 3","BAE01657.1//unnamed protein product [Macaca fascicularis]","3//A2MP1"]
[57168,3313,0.67,1.06,0.661831264105427,0.122530341429311,"*",0.0592478,"ASPHD2","NA","NA","NA","K00476//aspartate beta-hydroxylase [EC:1.14.11.16]","XP_021777112.1//aspartate beta-hydroxylase domain-containing protein 2 [Papio anubis]",4]
[89887,3867,6.48,10.25,0.661558191508184,{"v":7.62464668394366e-10,"d":"7.62E-10"},"*",{"v":8.47236e-11,"d":"8.47E-11"},"ZNF628","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","NP_149104.3//zinc finger protein 628 [Homo sapiens]","2//1"]
[90416,1723,4.52,7.14,0.659601301613912,0.00121608312098548,"*",3.46082E-4,"CCDC32","NA","NA","NA","K10392//kinesin family member 1;K17423//large subunit ribosomal protein L42","XP_008568451.1//PREDICTED: uncharacterized protein C15orf57 homolog isoform X3 [Galeopterus variegatus];NP_001074260.1//uncharacterized protein C15orf57 isoform 1 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[80176,3130,17.57,27.75,0.659373580116455,{"v":2.1675973539281e-20,"d":"2.17E-20"},"*",{"v":1.019072E-21,"d":"1.02E-21"},"SPSB1","NA","NA","NA","K10343//SPRY domain-containing SOCS box protein 1/4","BAD92796.1//SPRY domain-containing SOCS box protein SSB-1 variant, partial [Homo sapiens]","3//A2MP1"]
[400745,3753,4.54,7.17,0.65928082141099,{"v":1.49328406472968e-06,"d":"1.49E-06"},"*",{"v":2.54178e-07,"d":"2.54E-07"},"SH2D5","GO:0030054//cell junction;GO:0014069//postsynaptic density;GO:0045211//postsynaptic membrane","NA","NA","K18080//tensin;K22020//mucin-19","XP_008965308.1//PREDICTED: SH2 domain-containing protein 5 isoform X1 [Pan paniscus];XP_011935704.1//PREDICTED: SH2 domain-containing protein 5 isoform X1 [Cercocebus atys]","1//3"]
[717,1955,0.83,1.31,0.658383570190526,0.139052636895642,"*",0.0693174,"C2","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005576//extracellular region","GO:0004252//serine-type endopeptidase activity;GO:0046872//metal ion binding","GO:0006958//complement activation, classical pathway;GO:0030449//regulation of complement activation;GO:0006956//complement activation;GO:2000427//positive regulation of apoptotic cell clearance;GO:0007584//response to nutrient;GO:0045087//innate immune response","K01332//complement component 2 [EC:3.4.21.43]","NP_000054.2//complement C2 isoform 1 preproprotein [Homo sapiens];NP_001139375.1//complement C2 isoform 2 precursor [Homo sapiens];NP_001269388.1//complement C2 isoform 6 precursor [Homo sapiens];NP_001269387.1//complement C2 isoform 5 [Homo sapiens];NP_001171534.1//complement C2 isoform 3 [Homo sapiens];NP_001269386.1//complement C2 isoform 4 [Homo sapiens]","1//3;2//1;5"]
[29107,1176,33.5,52.87,0.658288231148445,{"v":2.05340060086133e-14,"d":"2.05E-14"},"*",{"v":1.492424E-15,"d":"1.49E-15"},"NXT1","NA","NA","NA","K14285//NTF2-related export protein 1/2","XP_012388659.1//PREDICTED: NTF2-related export protein 1 isoform X1 [Orcinus orca]","2//1"]
[2788,4264,0.52,0.82,0.657112286476991,0.0939109754897987,"*",0.0435104,"GNG7","NA","NA","NA","K04543//guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7","BAB15755.1//FLJ00058 protein, partial [Homo sapiens]","2//1"]
[770,1870,10.28,16.21,0.657043826323664,{"v":1.44020875255973E-7,"d":"1.44E-07"},"*",{"v":2.11334E-8,"d":"2.11E-08"},"CA11","GO:0005576//extracellular region","NA","NA","K01672//carbonic anhydrase [EC:4.2.1.1];K18245//carbonic anhydrase 2 [EC:4.2.1.1]","XP_005879554.1//PREDICTED: carbonic anhydrase-related protein 11 isoform X2 [Myotis brandtii]",4]
[3931,1354,3.28,5.17,0.656468465696851,0.0178288865031298,"*",0.00659738,"LCAT","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0034364//high-density lipoprotein particle;GO:0005576//extracellular region","GO:0004607//phosphatidylcholine-sterol O-acyltransferase activity;GO:0034186//apolipoprotein A-I binding","GO:0046470//phosphatidylcholine metabolic process;GO:0008203//cholesterol metabolic process;GO:0034435//cholesterol esterification;GO:0090107//regulation of high-density lipoprotein particle assembly;GO:0030301//cholesterol transport;GO:0034372//very-low-density lipoprotein particle remodeling;GO:0034375//high-density lipoprotein particle remodeling;GO:0006644//phospholipid metabolic process;GO:0042632//cholesterol homeostasis;GO:0043691//reverse cholesterol transport;GO:0042158//lipoprotein biosynthetic process;GO:0006656//phosphatidylcholine biosynthetic process","K00650//lecithin-cholesterol acyltransferase [EC:2.3.1.43]","NP_000220.1//phosphatidylcholine-sterol acyltransferase precursor [Homo sapiens]","1//3"]
[24142,1274,8.51,13.4,0.655001963659172,0.000240601238326996,"*",{"v":5.94198e-05,"d":"5.94E-05"},"NAT6","GO:0005737//cytoplasm","GO:0008080//N-acetyltransferase activity","NA","K00463//indoleamine 2,3-dioxygenase [EC:1.13.11.52];K11647//SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:3.6.4.-];K01197//hyaluronoglucosaminidase [EC:3.2.1.35];K06831//galectin-3","NP_036323.2//N-acetyltransferase 6 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[486,584,10.69,16.83,0.654773323609458,0.00627367872606635,"*",2.07172E-3,"FXYD2","GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0016323//basolateral plasma membrane;GO:0005890//sodium:potassium-exchanging ATPase complex;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane","GO:0005391//sodium:potassium-exchanging ATPase activity;GO:0005216//ion channel activity;GO:0017080//sodium channel regulator activity;GO:0005215//transporter activity","GO:0006810//transport;GO:0001558//regulation of cell growth;GO:1903779//regulation of cardiac conduction;GO:0034220//ion transmembrane transport;GO:0036376//sodium ion export across plasma membrane;GO:0042127//regulation of cell proliferation;GO:0090662//ATP hydrolysis coupled transmembrane transport;GO:2000649//regulation of sodium ion transmembrane transporter activity;GO:1990573//potassium ion import across plasma membrane","K01538//sodium/potassium-transporting ATPase subunit gamma (FXYD domain-containing ion transport regulator 2)","CAA60152.1//gamma subunit of sodium potassium ATPase like [Homo sapiens]","4;3//A2MP1"]
[57862,2652,15.95,25.09,0.653556046756941,{"v":6.12207022608696e-16,"d":"6.12E-16"},"*",{"v":3.96666e-17,"d":"3.97E-17"},"ZNF410","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","NP_001229855.1//zinc finger protein 410 isoform c [Homo sapiens];NP_067011.1//zinc finger protein 410 isoform b [Homo sapiens];NP_001229853.1//zinc finger protein 410 isoform a [Homo sapiens];XP_012914270.1//PREDICTED: zinc finger protein 410 isoform X3 [Mustela putorius furo];NP_001229856.1//zinc finger protein 410 isoform d [Homo sapiens]","1//3;2//1"]
[54936,1701,11.24,17.68,0.653476239170506,{"v":1.93246569656329e-07,"d":"1.93E-07"},"*",{"v":2.88648E-8,"d":"2.89E-08"},"ADPRHL2","GO:0005759//mitochondrial matrix;GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0005739//mitochondrion","GO:0004649//poly(ADP-ribose) glycohydrolase activity;GO:0046872//metal ion binding","GO:0071451//cellular response to superoxide","K11687//poly(ADP-ribose) glycohydrolase ARH3 [EC:3.2.1.143]","XP_007977605.1//PREDICTED: poly(ADP-ribose) glycohydrolase ARH3 isoform X2 [Chlorocebus sabaeus]","2//1"]
[26471,884,3.04,4.78,0.652939294537163,0.104551837637984,"*",0.0492128,"NUPR1","GO:0005634//nucleus;GO:0005829//cytosol;GO:0032993//protein-DNA complex","GO:0003677//DNA binding;GO:0003682//chromatin binding","GO:2000194//regulation of female gonad development;GO:0045786//negative regulation of cell cycle;GO:0006351//transcription, DNA-templated;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0006473//protein acetylation;GO:0048147//negative regulation of fibroblast proliferation;GO:0016049//cell growth;GO:0002526//acute inflammatory response;GO:0009636//response to toxic substance;GO:0008584//male gonad development;GO:0035914//skeletal muscle cell differentiation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0043065//positive regulation of apoptotic process;GO:0031401//positive regulation of protein modification process;GO:0006461//protein complex assembly","K15626//nuclear protein, 1","NP_036517.1//nuclear protein 1 isoform b [Homo sapiens];NP_001035948.1//nuclear protein 1 isoform a [Homo sapiens]","1//3;2//1"]
[80776,1049,7.52,11.82,0.652425468499895,0.00148569607530837,"*",0.000429786,"B9D2","GO:0016020//membrane;GO:0036064//ciliary basal body;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005813//centrosome;GO:0036038//MKS complex","GO:0043015//gamma-tubulin binding","GO:0060271//cilium assembly;GO:0097711//ciliary basal body-plasma membrane docking;GO:0007062//sister chromatid cohesion","K16745//B9 domain-containing protein 2","XP_006771929.1//PREDICTED: B9 domain-containing protein 2 isoform X1 [Myotis davidii]","3//A2MP1"]
[151516,2216,0.14,0.22,0.652076696579693,0.666421674730978,"*",0.546646,"ASPRV1","NA","NA","NA","NA","XP_005575723.1//PREDICTED: retroviral-like aspartic protease 1 [Macaca fascicularis]","2//1"]
[8532,2397,0.07,0.11,0.652076696579693,0.782311846582387,"*",0.685686,"CPZ","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005578//proteinaceous extracellular matrix","GO:0004185//serine-type carboxypeptidase activity;GO:0008270//zinc ion binding;GO:0004181//metallocarboxypeptidase activity","GO:0006508//proteolysis;GO:0016485//protein processing;GO:0006518//peptide metabolic process;GO:0016055//Wnt signaling pathway","K13022//carboxypeptidase Z [EC:3.4.17.-]","NP_003643.2//carboxypeptidase Z isoform 2 precursor [Homo sapiens];NP_001014447.1//carboxypeptidase Z isoform 1 precursor [Homo sapiens]","3//A2MP1;2//1"]
[729359,6353,0.07,0.11,0.652076696579693,0.608819056225238,"*",0.452136,"PLIN4","GO:0043231//intracellular membrane-bounded organelle;GO:0005811//lipid droplet;GO:0005829//cytosol;GO:0005886//plasma membrane","NA","NA","K20254//perilipin-4","NP_001073869.1//perilipin-4 [Homo sapiens]","1//3"]
[4685,4176,0.07,0.11,0.652076696579693,0.629096558617468,"*",0.505908,"NCAM2","GO:0030424//axon;GO:0016604//nuclear body;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0042802//identical protein binding","GO:0007413//axonal fasciculation;GO:0007608//sensory perception of smell;GO:0007158//neuron cell-cell adhesion","K06491//neural cell adhesion molecule","XP_020926518.1//neural cell adhesion molecule 2 isoform X2 [Sus scrofa];NP_001339526.1//neural cell adhesion molecule 2 isoform 8 [Homo sapiens];XP_020926517.1//neural cell adhesion molecule 2 isoform X1 [Sus scrofa];NP_001339521.1//neural cell adhesion molecule 2 isoform 3 [Homo sapiens];NP_001339524.1//neural cell adhesion molecule 2 isoform 6 precursor [Homo sapiens]","4;1//3"]
[56103,4602,0.07,0.11,0.652076696579693,0.666167470552334,"*",0.546646,"PCDHGB2","NA","NA","NA","K16496//protocadherin gamma subfamily B","NP_001076031.1//protocadherin gamma-B2 precursor [Pan troglodytes]","1//3;2//1"]
[392490,2269,0.07,0.11,0.652076696579693,0.781474612157534,"*",0.685686,"FLJ44635","GO:0070062//extracellular exosome;GO:0005737//cytoplasm","GO:0005509//calcium ion binding;GO:0008017//microtubule binding","GO:0030154//cell differentiation","K01115//phospholipase D1/2 [EC:3.1.4.4]","NP_997305.2//TPT1-like protein [Homo sapiens]","2//1"]
[5798,3570,0.07,0.11,0.652076696579693,0.628558325581395,"*",0.505908,"PTPRN","GO:0030658//transport vesicle membrane;GO:0030424//axon;GO:0005634//nucleus;GO:0030054//cell junction;GO:0043204//perikaryon;GO:0043025//neuronal cell body;GO:0005768//endosome;GO:0030141//secretory granule;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0043679//axon terminus;GO:0045202//synapse;GO:0005886//plasma membrane","GO:0044389//ubiquitin-like protein ligase binding;GO:0051020//GTPase binding;GO:0008134//transcription factor binding;GO:0030507//spectrin binding","GO:1904692//positive regulation of type B pancreatic cell proliferation;GO:0032868//response to insulin;GO:0051591//response to cAMP;GO:0006351//transcription, DNA-templated;GO:0043627//response to estrogen;GO:0030073//insulin secretion;GO:0000302//response to reactive oxygen species;GO:0035773//insulin secretion involved in cellular response to glucose stimulus;GO:0001553//luteinization;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0019221//cytokine-mediated signaling pathway;GO:1990502//dense core granule maturation","K07817//receptor-type tyrosine-protein phosphatase N [EC:3.1.3.48]","NP_001186692.1//receptor-type tyrosine-protein phosphatase-like N isoform 2 precursor [Homo sapiens];NP_002837.1//receptor-type tyrosine-protein phosphatase-like N isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[170958,6153,0.07,0.11,0.652076696579693,0.578487,"*",0.421824,"ZNF525","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0035556//intracellular signal transduction","K09228//KRAB domain-containing zinc finger protein","XP_011766061.1//PREDICTED: zinc finger protein 761 isoform X2 [Macaca nemestrina];XP_016789852.1//PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 813-like [Pan troglodytes]","1//3"]
[3484,1608,4.92,7.73,0.651810098585608,0.00134528754789439,"*",0.000385968,"IGFBP1","GO:0005615//extracellular space;GO:0005794//Golgi apparatus;GO:0005576//extracellular region","GO:0005520//insulin-like growth factor binding;GO:0031994//insulin-like growth factor I binding;GO:0031995//insulin-like growth factor II binding","GO:0001558//regulation of cell growth","K10138//insulin-like growth factor-binding protein 3","XP_519083.3//PREDICTED: insulin-like growth factor-binding protein 1 [Pan troglodytes]","3//A2MP1"]
[64761,3824,4.76,7.47,0.650146669481294,{"v":3.48099813538711e-07,"d":"3.48E-07"},"*",{"v":5.376E-8,"d":"5.38E-08"},"PARP12","GO:0005634//nucleus","GO:0003723//RNA binding;GO:0046872//metal ion binding;GO:0003950//NAD+ ADP-ribosyltransferase activity","NA","K15259//poly [ADP-ribose] polymerase 7/11/12/13 [EC:2.4.2.30]","NP_073587.1//poly [ADP-ribose] polymerase 12 [Homo sapiens]","3//A2MP1"]
[1662,3289,13.34,20.93,0.649813645071124,{"v":6.52962281581485e-16,"d":"6.53E-16"},"*",{"v":4.2389e-17,"d":"4.24E-17"},"DDX10","GO:0005730//nucleolus;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0004004//ATP-dependent RNA helicase activity;GO:0005524//ATP binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity","GO:0010501//RNA secondary structure unwinding","K14776//ATP-dependent RNA helicase DDX10/DBP4 [EC:3.6.4.13]","XP_008951975.1//PREDICTED: probable ATP-dependent RNA helicase DDX10 [Pan paniscus]","3//A2MP1"]
[10865,2114,5.1,8,0.649502752915867,0.000315721365247525,"*",{"v":7.98494e-05,"d":"7.98E-05"},"ARID5A","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus","GO:0003723//RNA binding;GO:0030331//estrogen receptor binding;GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0046966//thyroid hormone receptor binding;GO:0044212//transcription regulatory region DNA binding;GO:0001227//transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0046965//retinoid X receptor binding;GO:0050681//androgen receptor binding;GO:0043565//sequence-specific DNA binding;GO:0008134//transcription factor binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0071391//cellular response to estrogen stimulus;GO:0006351//transcription, DNA-templated;GO:0045087//innate immune response","K19479//collagen, type X, alpha;K16628//collagen, type VII, alpha;K06676//condensin complex subunit 2;K07874//Ras-related protein Rab-1A;K00844//hexokinase [EC:2.7.1.1];K19720//collagen, type III, alpha;K19195//AT-rich interactive domain-containing protein 4B","NP_001306016.1//AT-rich interactive domain-containing protein 5A isoform b [Homo sapiens];NP_001306014.1//AT-rich interactive domain-containing protein 5A isoform a [Homo sapiens];AAA36325.1//modulator recognition factor I, partial [Homo sapiens]","1//3;2//1"]
[124783,1297,0.44,0.69,0.649092838140872,0.512174981681034,"*",0.357054,"SPATA32","GO:0048471//perinuclear region of cytoplasm","GO:0003779//actin binding","GO:0007283//spermatogenesis","NA","NP_689556.2//spermatogenesis-associated protein 32 [Homo sapiens]","2//1"]
[5721,829,90.47,141.85,0.64885477403787,{"v":2.14277010888889e-25,"d":"2.14E-25"},"*",{"v":7.24362e-27,"d":"7.24E-27"},"PSME2","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005654//nucleoplasm;GO:0000502//proteasome complex;GO:0005829//cytosol;GO:0008537//proteasome activator complex;GO:0005737//cytoplasm","GO:0061133//endopeptidase activator activity;GO:0042802//identical protein binding","GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:0043687//post-translational protein modification;GO:0038061//NIK/NF-kappaB signaling;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0006521//regulation of cellular amino acid metabolic process;GO:0010950//positive regulation of endopeptidase activity;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0016579//protein deubiquitination;GO:0043488//regulation of mRNA stability;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0000209//protein polyubiquitination;GO:0035722//interleukin-12-mediated signaling pathway;GO:0055085//transmembrane transport;GO:0000165//MAPK cascade;GO:0050852//T cell receptor signaling pathway;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0061136//regulation of proteasomal protein catabolic process;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:1902036//regulation of hematopoietic stem cell differentiation","K06697//proteasome activator subunit 2 (PA28 beta)","NP_002809.2//proteasome activator complex subunit 2 [Homo sapiens]","2//1"]
[5873,3455,4.28,6.71,0.648701969799036,{"v":8.23628424722041e-06,"d":"8.24E-06"},"*",{"v":1.576722e-06,"d":"1.58E-06"},"RAB27A","GO:0030425//dendrite;GO:0005770//late endosome;GO:0016324//apical plasma membrane;GO:0033093//Weibel-Palade body;GO:0042470//melanosome;GO:0005829//cytosol;GO:0005576//extracellular region;GO:0045202//synapse;GO:0070382//exocytic vesicle;GO:0070062//extracellular exosome;GO:0030667//secretory granule membrane;GO:0035580//specific granule lumen;GO:0032585//multivesicular body membrane;GO:0005764//lysosome;GO:0033162//melanosome membrane;GO:0001750//photoreceptor outer segment;GO:0030141//secretory granule;GO:0005794//Golgi apparatus","GO:0019904//protein domain specific binding;GO:0019003//GDP binding;GO:0031489//myosin V binding;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0048489//synaptic vesicle transport;GO:0007596//blood coagulation;GO:1903428//positive regulation of reactive oxygen species biosynthetic process;GO:0045921//positive regulation of exocytosis;GO:0050766//positive regulation of phagocytosis;GO:0043320//natural killer cell degranulation;GO:0036257//multivesicular body organization;GO:0043312//neutrophil degranulation;GO:0030318//melanocyte differentiation;GO:0006605//protein targeting;GO:0019882//antigen processing and presentation;GO:1903307//positive regulation of regulated secretory pathway;GO:0071985//multivesicular body sorting pathway;GO:0010628//positive regulation of gene expression;GO:0032400//melanosome localization;GO:0061024//membrane organization;GO:0043316//cytotoxic T cell degranulation;GO:0032402//melanosome transport;GO:0097278//complement-dependent cytotoxicity;GO:1990182//exosomal secretion;GO:0006887//exocytosis;GO:1903435//positive regulation of constitutive secretory pathway","K07885//Ras-related protein Rab-27A","NP_004571.2//ras-related protein Rab-27A [Homo sapiens]","4;2//1"]
[199746,741,35.32,55.28,0.646272272739792,{"v":1.76261137547272e-09,"d":"1.76E-09"},"*",{"v":2.04244e-10,"d":"2.04E-10"},"U2AF1L4","GO:0005654//nucleoplasm;GO:0089701//U2AF;GO:0005681//spliceosomal complex;GO:0016607//nuclear speck;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0046872//metal ion binding;GO:0030628//pre-mRNA 3'-splice site binding","GO:0006406//mRNA export from nucleus;GO:0000398//mRNA splicing, via spliceosome;GO:0006369//termination of RNA polymerase II transcription;GO:0031124//mRNA 3'-end processing;GO:0006405//RNA export from nucleus","K12836//splicing factor U2AF 35 kDa subunit","NP_659424.2//splicing factor U2AF 26 kDa subunit isoform 2 [Homo sapiens];NP_001035515.1//splicing factor U2AF 26 kDa subunit isoform 1 [Homo sapiens]","3//A2MP1;2//1"]
[100534599,5068,2.5,3.91,0.645240512645265,{"v":3.54899147399182e-05,"d":"3.55E-05"},"*",{"v":7.60276E-6,"d":"7.60E-06"},"ISY1-RAB43","NA","NA","NA","K12870//pre-mRNA-splicing factor ISY1","XP_001094091.1//PREDICTED: pre-mRNA-splicing factor ISY1 homolog [Macaca mulatta]","1//3"]
[5606,2318,39.64,61.96,0.64438018160308,{"v":1.40371165225225e-29,"d":"1.40E-29"},"*",{"v":3.90164E-31,"d":"3.90E-31"},"MAP2K3","GO:0016020//membrane;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005737//cytoplasm","GO:0004713//protein tyrosine kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004708//MAP kinase kinase activity;GO:0019901//protein kinase binding","GO:0023014//signal transduction by protein phosphorylation;GO:0042035//regulation of cytokine biosynthetic process;GO:0007165//signal transduction;GO:0007346//regulation of mitotic cell cycle;GO:0000187//activation of MAPK activity;GO:0032147//activation of protein kinase activity;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006954//inflammatory response;GO:0060048//cardiac muscle contraction;GO:0035897//proteolysis in other organism;GO:0045860//positive regulation of protein kinase activity;GO:0031098//stress-activated protein kinase signaling cascade;GO:0042981//regulation of apoptotic process","K04432//mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]","NP_659731.1//dual specificity mitogen-activated protein kinase kinase 3 isoform B [Homo sapiens];XP_016880346.1//PREDICTED: dual specificity mitogen-activated protein kinase kinase 3 isoform X2 [Homo sapiens]","4;1//3;2//1"]
[2006,3468,0.32,0.5,0.643856189774725,0.3127624346543,"*",0.18577,"ELN","GO:0031012//extracellular matrix;GO:0071953//elastic fiber;GO:0005576//extracellular region;GO:0005739//mitochondrion;GO:0005578//proteinaceous extracellular matrix","GO:0005201//extracellular matrix structural constituent;GO:0050840//extracellular matrix binding","GO:0030833//regulation of actin filament polymerization;GO:0022617//extracellular matrix disassembly;GO:0008015//blood circulation;GO:0007585//respiratory gaseous exchange;GO:0009887//animal organ morphogenesis;GO:0008283//cell proliferation;GO:0030198//extracellular matrix organization;GO:0007519//skeletal muscle tissue development;GO:0043149//stress fiber assembly","K14211//elastin","NP_001265845.1//elastin isoform j precursor [Homo sapiens];NP_001265842.1//elastin isoform g precursor [Homo sapiens];CAD98065.1//hypothetical protein, partial [Homo sapiens];NP_001075222.1//elastin isoform c precursor [Homo sapiens];NP_001265844.1//elastin isoform i precursor [Homo sapiens];NP_001075224.1//elastin isoform e precursor [Homo sapiens];NP_001265846.1//elastin isoform k precursor [Homo sapiens];NP_000492.2//elastin isoform a precursor [Homo sapiens];NP_001265841.1//elastin isoform f precursor [Homo sapiens];NP_001265868.1//elastin isoform m precursor [Homo sapiens];NP_001265847.1//elastin isoform l precursor [Homo sapiens];NP_001265843.1//elastin isoform h precursor [Homo sapiens];NP_001075223.1//elastin isoform d precursor [Homo sapiens]","1//3;3//A2MP1;2//1"]
[7357,4028,8.84,13.8,0.6425499922741,{"v":8.28301291704374e-13,"d":"8.28E-13"},"*",{"v":6.87572e-14,"d":"6.88E-14"},"UGCG","GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0016757//transferase activity, transferring glycosyl groups;GO:0102769//dihydroceramide glucosyltransferase activity;GO:0008120//ceramide glucosyltransferase activity","GO:0006688//glycosphingolipid biosynthetic process;GO:0006679//glucosylceramide biosynthetic process;GO:0008544//epidermis development;GO:1903955//positive regulation of protein targeting to mitochondrion;GO:0006687//glycosphingolipid metabolic process","K00720//ceramide glucosyltransferase [EC:2.4.1.80]","XP_011738666.1//PREDICTED: ceramide glucosyltransferase [Macaca nemestrina]","2//1"]
[57559,2094,9.08,14.17,0.642075555627104,{"v":3.47485673803731e-07,"d":"3.47E-07"},"*",{"v":5.36434e-08,"d":"5.36E-08"},"STAMBPL1","GO:0016020//membrane;GO:0005829//cytosol","GO:0061578//Lys63-specific deubiquitinase activity;GO:0046872//metal ion binding;GO:0008237//metallopeptidase activity","GO:0016579//protein deubiquitination","K11867//AMSH-like protease [EC:3.4.19.12]","NP_065850.1//AMSH-like protease [Homo sapiens]","3//A2MP1"]
[8798,970,27.29,42.56,0.641125756227049,{"v":1.68086696690179E-9,"d":"1.68E-09"},"*",{"v":1.9393E-10,"d":"1.94E-10"},"DYRK4","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0004713//protein tyrosine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0046872//metal ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding","NA","K18669//dual specificity tyrosine-phosphorylation-regulated kinase 2/3/4 [EC:2.7.12.1]","AAF91393.1//protein kinase DYRK4, partial [Homo sapiens];BAF85011.1//unnamed protein product [Homo sapiens];EAW88842.1//dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4, isoform CRA_b [Homo sapiens]","1//3;2//1"]
[345275,2289,1.18,1.84,0.640918906695172,0.0854714207464325,"*",0.0389956,"HSD17B13","GO:0005811//lipid droplet;GO:0005829//cytosol;GO:0005576//extracellular region","GO:0016491//oxidoreductase activity","GO:0034389//lipid particle organization;GO:0046889//positive regulation of lipid biosynthetic process","K15734//all-trans-retinol dehydrogenase (NAD+) [EC:1.1.1.105]","NP_835236.2//17-beta-hydroxysteroid dehydrogenase 13 isoform A precursor [Homo sapiens];NP_001129702.1//17-beta-hydroxysteroid dehydrogenase 13 isoform B [Homo sapiens]","4;2//1"]
[2742,3190,0.18,0.28,0.637429920615292,0.402849419031075,"*",0.26132,"GLRA2","GO:0042995//cell projection;GO:0005887//integral component of plasma membrane;GO:0030054//cell junction;GO:0034707//chloride channel complex;GO:0005886//plasma membrane;GO:0045211//postsynaptic membrane","GO:0022824//transmitter-gated ion channel activity;GO:0046872//metal ion binding;GO:0022852//glycine-gated chloride ion channel activity;GO:0016594//glycine binding;GO:0016934//extracellularly glycine-gated chloride channel activity","GO:0071361//cellular response to ethanol;GO:0043200//response to amino acid;GO:0034220//ion transmembrane transport;GO:0071294//cellular response to zinc ion;GO:0007218//neuropeptide signaling pathway;GO:0060012//synaptic transmission, glycinergic;GO:1902476//chloride transmembrane transport;GO:0071230//cellular response to amino acid stimulus","K05194//glycine receptor alpha-2","ERE65914.1//glycine receptor subunit alpha-2-like isoform 2 [Cricetulus griseus]","1//3;3//A2MP1"]
[10561,1742,0.09,0.14,0.637429920615292,0.781530372029968,"*",0.685686,"IFI44","GO:0005737//cytoplasm","NA","GO:0009615//response to virus","NA","NP_006408.3//interferon-induced protein 44 [Homo sapiens]",4]
[2695,711,6.39,9.94,0.637429920615292,0.0265994126587174,"*",0.01033404,"GIP","GO:0034774//secretory granule lumen;GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0043025//neuronal cell body","GO:0005179//hormone activity","GO:0014070//response to organic cyclic compound;GO:0043200//response to amino acid;GO:0032024//positive regulation of insulin secretion;GO:0070094//positive regulation of glucagon secretion;GO:0008344//adult locomotory behavior;GO:0050796//regulation of insulin secretion;GO:0010828//positive regulation of glucose transport;GO:0055123//digestive system development;GO:0070328//triglyceride homeostasis;GO:0060291//long-term synaptic potentiation;GO:0019233//sensory perception of pain;GO:0010269//response to selenium ion;GO:0009749//response to glucose;GO:0043950//positive regulation of cAMP-mediated signaling;GO:0033993//response to lipid;GO:0007565//female pregnancy;GO:0042493//response to drug;GO:0007165//signal transduction;GO:0048678//response to axon injury;GO:0043434//response to peptide hormone;GO:0031018//endocrine pancreas development;GO:0007613//memory;GO:0042594//response to starvation;GO:0035640//exploration behavior;GO:0010447//response to acidic pH","K05258//gastric inhibitory polypeptide","NP_004114.1//gastric inhibitory polypeptide preproprotein [Homo sapiens]","2//1"]
[6580,1921,0.27,0.42,0.637429920615292,0.48250390964792,"*",0.330298,"SLC22A1","GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane","GO:0008513//secondary active organic cation transmembrane transporter activity;GO:0015101//organic cation transmembrane transporter activity;GO:0008514//organic anion transmembrane transporter activity;GO:0015651//quaternary ammonium group transmembrane transporter activity;GO:0042803//protein homodimerization activity;GO:0005333//norepinephrine transmembrane transporter activity;GO:0005329//dopamine transmembrane transporter activity;GO:0005277//acetylcholine transmembrane transporter activity","GO:0015695//organic cation transport;GO:0048241//epinephrine transport;GO:0051260//protein homooligomerization;GO:0015874//norepinephrine transport;GO:0015872//dopamine transport;GO:0006836//neurotransmitter transport;GO:0006855//drug transmembrane transport;GO:0010248//establishment or maintenance of transmembrane electrochemical gradient","K08198//MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 1","XP_011831306.1//PREDICTED: solute carrier family 22 member 1 isoform X1 [Mandrillus leucophaeus];NP_694857.1//solute carrier family 22 member 1 isoform b [Homo sapiens]","1//3;2//1"]
[121268,1291,2.38,3.7,0.636563697208369,0.103084296478122,"*",0.0483736,"RHEBL1","GO:0016020//membrane;GO:0012505//endomembrane system;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0031929//TOR signaling;GO:0007165//signal transduction;GO:0051092//positive regulation of NF-kappaB transcription factor activity","K07849//Ras homolog enriched in brain like 1","NP_001290055.1//GTPase RhebL1 isoform 2 [Homo sapiens];NP_653194.1//GTPase RhebL1 isoform 1 precursor [Homo sapiens]","1//3;2//1"]
[54453,4265,7.36,11.44,0.636309380721376,{"v":1.37886134575119e-11,"d":"1.38E-11"},"*",{"v":1.269754E-12,"d":"1.27E-12"},"RIN2","GO:0005829//cytosol","GO:0017112//Rab guanyl-nucleotide exchange factor activity;GO:0030695//GTPase regulator activity;GO:0005096//GTPase activator activity","GO:0007165//signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0006897//endocytosis;GO:0061024//membrane organization","K17638//Ras and Rab interactor 1","XP_011527557.2//PREDICTED: ras and Rab interactor 2 isoform X1 [Homo sapiens];NP_001229510.1//ras and Rab interactor 2 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[253982,1562,6.73,10.45,0.634824532357928,0.0002777447302,"*",{"v":6.95492e-05,"d":"6.95E-05"},"ASPHD1","GO:0016021//integral component of membrane","GO:0051213//dioxygenase activity","GO:0018193//peptidyl-amino acid modification","K00476//aspartate beta-hydroxylase [EC:1.14.11.16]","NP_859069.2//aspartate beta-hydroxylase domain-containing protein 1 [Homo sapiens]","3//A2MP1"]
[100289187,1549,0.67,1.04,0.63435052768332,0.366854845710821,"*",0.227292,"TMEM225B","GO:0016021//integral component of membrane","NA","GO:0010923//negative regulation of phosphatase activity","NA","XP_011513993.1//PREDICTED: transmembrane protein 225-like isoform X1 [Homo sapiens]","2//1"]
[2120,5989,3.72,5.77,0.633268697537451,{"v":3.28642751269036e-08,"d":"3.29E-08"},"*",{"v":4.4583e-09,"d":"4.46E-09"},"ETV6","GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005829//cytosol","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0019904//protein domain specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0001227//transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0022008//neurogenesis;GO:0071425//hematopoietic stem cell proliferation;GO:0030154//cell differentiation;GO:0007296//vitellogenesis;GO:0097152//mesenchymal cell apoptotic process","K03211//ETS translocation variant 6/7","NP_001978.1//transcription factor ETV6 [Homo sapiens]",4]
[2357,1334,0.98,1.52,0.633217669328377,0.280984461058109,"*",0.1622512,"FPR1","GO:0030667//secretory granule membrane;GO:0005887//integral component of plasma membrane;GO:0101003//ficolin-1-rich granule membrane;GO:0005622//intracellular;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0035577//azurophil granule membrane","GO:0050786//RAGE receptor binding;GO:0005124//scavenger receptor binding;GO:0004875//complement receptor activity;GO:0004982//N-formyl peptide receptor activity","GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007165//signal transduction;GO:0000187//activation of MAPK activity;GO:0050900//leukocyte migration;GO:0007263//nitric oxide mediated signal transduction;GO:0006954//inflammatory response;GO:0002430//complement receptor mediated signaling pathway;GO:0060326//cell chemotaxis;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0043312//neutrophil degranulation;GO:0006935//chemotaxis;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway","K04172//formyl peptide receptor 1","NP_002020.1//fMet-Leu-Phe receptor [Homo sapiens]","1//3;3//A2MP1"]
[642843,647,1.18,1.83,0.633056788922201,0.453425674479167,"*",0.305198,"CPSF4L","NA","NA","NA","K14404//cleavage and polyadenylation specificity factor subunit 4","XP_011523417.1//PREDICTED: putative cleavage and polyadenylation specificity factor subunit 4-like protein isoform X1 [Homo sapiens]","1//3"]
[126326,4317,0.2,0.31,0.632268215499513,0.404609975894321,"*",0.26269,"GIPC3","NA","NA","NA","K20056//PDZ domain-containing protein GIPC","XP_005259549.1//PREDICTED: PDZ domain-containing protein GIPC3 isoform X1 [Homo sapiens]","2//1"]
[79883,3137,0.4,0.62,0.632268215499513,0.32906739949927,"*",0.1974734,"PODNL1","GO:0005737//cytoplasm;GO:0005578//proteinaceous extracellular matrix","GO:0004860//protein kinase inhibitor activity","GO:0006469//negative regulation of protein kinase activity;GO:0046426//negative regulation of JAK-STAT cascade;GO:0019221//cytokine-mediated signaling pathway","K08119//extracellular matrix protein 2","NP_079101.3//podocan-like protein 1 isoform 1 precursor [Homo sapiens];NP_001139727.1//podocan-like protein 1 isoform 3 precursor [Homo sapiens];NP_001139726.1//podocan-like protein 1 isoform 2 precursor [Homo sapiens]","4;1//3"]
[1390,1613,12.05,18.67,0.631688781108878,{"v":8.97462155307263e-10,"d":"8.97E-10"},"*",{"v":1.00567E-10,"d":"1.01E-10"},"CREM","GO:0005634//nucleus;GO:0005667//transcription factor complex;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0008140//cAMP response element binding protein binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0001227//transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding","GO:0006006//glucose metabolic process;GO:0007165//signal transduction;GO:0030154//cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0048384//retinoic acid receptor signaling pathway;GO:0006351//transcription, DNA-templated;GO:0007283//spermatogenesis;GO:0048511//rhythmic process;GO:0006687//glycosphingolipid metabolic process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0042752//regulation of circadian rhythm;GO:0006631//fatty acid metabolic process;GO:0007275//multicellular organism development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter","K09052//cAMP response element modulator","NP_001254498.1//cAMP-responsive element modulator isoform 30 [Homo sapiens];NP_853549.1//cAMP-responsive element modulator isoform 1 [Homo sapiens];NP_898831.1//cAMP-responsive element modulator isoform 19 [Homo sapiens];XP_008998429.1//PREDICTED: cAMP-responsive element modulator isoform X22 [Callithrix jacchus];NP_898829.1//cAMP-responsive element modulator isoform 21 [Homo sapiens];XP_006717445.1//PREDICTED: cAMP-responsive element modulator isoform X13 [Homo sapiens];XP_017818215.1//cAMP-responsive element modulator isoform X35 [Papio anubis];XP_016818486.1//PREDICTED: cAMP-responsive element modulator isoform X2 [Pan troglodytes];NP_001254499.1//cAMP-responsive element modulator isoform 31 [Homo sapiens];XP_008998428.1//PREDICTED: cAMP-responsive element modulator isoform X21 [Callithrix jacchus];XP_003468673.3//PREDICTED: cAMP-responsive element modulator isoform X7 [Cavia porcellus];NP_877573.1//cAMP-responsive element modulator isoform 16 [Homo sapiens];XP_005003284.2//PREDICTED: cAMP-responsive element modulator isoform X10 [Cavia porcellus];NP_001254494.1//cAMP-responsive element modulator isoform 26 [Homo sapiens];NP_001254491.1//cAMP-responsive element modulator isoform 23 [Homo sapiens];NP_001254493.1//cAMP-responsive element modulator isoform 25 [Homo sapiens];EAW85916.1//cAMP responsive element modulator, isoform CRA_a [Homo sapiens];XP_008998430.1//PREDICTED: cAMP-responsive element modulator isoform X23 [Callithrix jacchus];XP_008965826.1//PREDICTED: cAMP-responsive element modulator isoform X5 [Pan paniscus];NP_877572.1//cAMP-responsive element modulator isoform 15 [Homo sapiens];NP_001254495.1//cAMP-responsive element modulator isoform 27 [Homo sapiens];NP_898830.1//cAMP-responsive element modulator isoform 20 [Homo sapiens];AAC60617.2//cyclic AMP-responsive element modulator beta isoform [Homo sapiens];NP_001254497.1//cAMP-responsive element modulator isoform 29 [Homo sapiens];NP_874393.1//cAMP-responsive element modulator isoform 11 [Homo sapiens];XP_005003283.2//PREDICTED: cAMP-responsive element modulator isoform X8 [Cavia porcellus];NP_874390.1//cAMP-responsive element modulator isoform 8 [Homo sapiens];XP_021568059.1//cAMP-responsive element modulator isoform X9 [Carlito syrichta];NP_898883.1//cAMP-responsive element modulator isoform 22 [Homo sapiens];XP_008998431.1//PREDICTED: cAMP-responsive element modulator isoform X24 [Callithrix jacchus]","1//3;3//A2MP1;2//1"]
[221481,1150,0.71,1.1,0.631612594019978,0.475806426289701,"*",0.324492,"ARMC12","GO:0005634//nucleus","NA","NA","NA","NP_659465.2//armadillo repeat-containing protein 12 isoform a [Homo sapiens];NP_001273505.1//armadillo repeat-containing protein 12 isoform c [Homo sapiens];NP_001273503.1//armadillo repeat-containing protein 12 isoform b [Homo sapiens]","4;1//3"]
[602,1864,113.75,176.11,0.630610286292771,{"v":9.31566982972973e-69,"d":"9.32E-69"},"*",{"v":8.63102e-71,"d":"8.63E-71"},"BCL3","NA","NA","NA","K09258//B-cell CLL/lymphoma protein 3","XP_011525499.2//PREDICTED: B-cell lymphoma 3 protein isoform X1 [Homo sapiens]",4]
[26024,5505,3.79,5.86,0.628702816251156,{"v":1.4859968207748e-07,"d":"1.49E-07"},"*",{"v":2.18518e-08,"d":"2.19E-08"},"PTCD1","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0003723//RNA binding;GO:0000049//tRNA binding","GO:0042780//tRNA 3'-end processing","K17710//pentatricopeptide repeat domain-containing protein 1","NP_001185808.1//ATP5J2-PTCD1 fusion protein [Homo sapiens]","3//A2MP1"]
[84696,1471,1.21,1.87,0.628031222613042,0.204252000420266,"*",0.1095294,"ABHD1","GO:0016021//integral component of membrane","GO:0016787//hydrolase activity;GO:0052689//carboxylic ester hydrolase activity;GO:0016298//lipase activity","GO:0044255//cellular lipid metabolic process","K13696//abhydrolase domain-containing protein 1/3","XP_011806780.1//PREDICTED: abhydrolase domain-containing protein 1 [Colobus angolensis palliatus]","3//A2MP1"]
[4163,8262,0.11,0.17,0.628031222613042,0.404570966062476,"*",0.26269,"MCC","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0030027//lamellipodium;GO:0005737//cytoplasm","GO:0004872//receptor activity","GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0045184//establishment of protein localization;GO:0007165//signal transduction;GO:0016055//Wnt signaling pathway;GO:0050680//negative regulation of epithelial cell proliferation;GO:0010633//negative regulation of epithelial cell migration","K21881//Usher syndrome type-1C protein-binding protein 1","NP_002378.1//colorectal mutant cancer protein isoform 2 [Homo sapiens];NP_001078846.1//colorectal mutant cancer protein isoform 1 [Homo sapiens]","1//3;2//1"]
[5979,4114,0.11,0.17,0.628031222613042,0.745427889661164,"*",0.644538,"RET","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0010008//endosome membrane;GO:0030425//dendrite;GO:0030424//axon;GO:0098797//plasma membrane protein complex;GO:0043235//receptor complex;GO:0043025//neuronal cell body;GO:0005887//integral component of plasma membrane;GO:0045121//membrane raft;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005769//early endosome","GO:0004713//protein tyrosine kinase activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005524//ATP binding;GO:0004872//receptor activity;GO:0005509//calcium ion binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity","GO:0030335//positive regulation of cell migration;GO:0061146//Peyer's patch morphogenesis;GO:0033619//membrane protein proteolysis;GO:0007411//axon guidance;GO:0007158//neuron cell-cell adhesion;GO:0035799//ureter maturation;GO:0042493//response to drug;GO:0007165//signal transduction;GO:0001755//neural crest cell migration;GO:0006468//protein phosphorylation;GO:0045793//positive regulation of cell size;GO:0071300//cellular response to retinoic acid;GO:0033141//positive regulation of peptidyl-serine phosphorylation of STAT protein;GO:2001241//positive regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0060041//retina development in camera-type eye;GO:0045893//positive regulation of transcription, DNA-templated;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0014042//positive regulation of neuron maturation;GO:0048265//response to pain;GO:0050770//regulation of axonogenesis;GO:0030155//regulation of cell adhesion;GO:0097021//lymphocyte migration into lymphoid organs;GO:0001838//embryonic epithelial tube formation;GO:0000165//MAPK cascade;GO:0060384//innervation;GO:0007497//posterior midgut development;GO:0010976//positive regulation of neuron projection development;GO:0048484//enteric nervous system development;GO:0001657//ureteric bud development;GO:0042551//neuron maturation;GO:0033630//positive regulation of cell adhesion mediated by integrin;GO:0072300//positive regulation of metanephric glomerulus development","K05126//proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]","NP_065681.1//proto-oncogene tyrosine-protein kinase receptor Ret isoform c precursor [Homo sapiens];NP_066124.1//proto-oncogene tyrosine-protein kinase receptor Ret isoform a precursor [Homo sapiens]","1//3;5"]
[266812,2338,0.44,0.68,0.628031222613042,0.366780726133953,"*",0.227292,"NAP1L5","GO:0005634//nucleus","NA","GO:0006334//nucleosome assembly","K19475//WAS/WASL-interacting protein","XP_011230419.1//PREDICTED: nucleosome assembly protein 1-like 5 [Ailuropoda melanoleuca]","3//A2MP1"]
[64167,5285,0.92,1.42,0.626185163447669,0.0146429441484565,"*",5.28554E-3,"ERAP2","GO:0005788//endoplasmic reticulum lumen;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005737//cytoplasm;GO:0005886//plasma membrane","GO:0004175//endopeptidase activity;GO:0008237//metallopeptidase activity;GO:0004177//aminopeptidase activity;GO:0008270//zinc ion binding;GO:0042277//peptide binding;GO:0070006//metalloaminopeptidase activity","GO:0008217//regulation of blood pressure;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0043171//peptide catabolic process;GO:0019885//antigen processing and presentation of endogenous peptide antigen via MHC class I;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0002250//adaptive immune response;GO:0006508//proteolysis","K13723//endoplasmic reticulum aminopeptidase 2 [EC:3.4.11.-]","NP_071745.1//endoplasmic reticulum aminopeptidase 2 isoform 1 [Homo sapiens];NP_001316162.1//endoplasmic reticulum aminopeptidase 2 isoform 3 [Homo sapiens];NP_001316158.1//endoplasmic reticulum aminopeptidase 2 isoform 2 [Homo sapiens]","4;1//3;2//1"]
[84436,3995,0.46,0.71,0.626185163447669,0.174873606976185,"*",0.0910166,"ZNF528","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_018871773.1//PREDICTED: zinc finger protein 528 isoform X1 [Gorilla gorilla gorilla]","2//1"]
[4824,3067,2.95,4.55,0.625151590836855,0.00205204047811448,"*",0.000610448,"NKX3-1","GO:0005634//nucleus;GO:0005622//intracellular","GO:0030331//estrogen receptor binding;GO:0030284//estrogen receptor activity;GO:0004882//androgen receptor activity;GO:0001047//core promoter binding","GO:0060442//branching involved in prostate gland morphogenesis;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0030521//androgen receptor signaling pathway;GO:0048754//branching morphogenesis of an epithelial tube","K09348//homeobox protein Nkx-3.1","NP_001243268.1//homeobox protein Nkx-3.1 isoform 2 [Homo sapiens];NP_006158.2//homeobox protein Nkx-3.1 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[147807,1144,15.59,24.03,0.624215720432082,{"v":2.50295586382979E-6,"d":"2.50E-06"},"*",{"v":4.41864e-07,"d":"4.42E-07"},"ZNF524","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_014712194.1//PREDICTED: zinc finger protein 865 [Equus asinus]","3//A2MP1"]
[55850,877,4.73,7.28,0.622098266859301,0.0393996274939024,"*",0.01618014,"USE1","NA","NA","NA","K08507//unconventional SNARE in the endoplasmic reticulum protein 1","XP_004060298.1//PREDICTED: vesicle transport protein USE1 [Gorilla gorilla gorilla]","3//A2MP1"]
[23179,4928,0.13,0.2,0.62148837674627,0.429971245761909,"*",0.284216,"RGL1","GO:0005829//cytosol;GO:0005622//intracellular","GO:0008321//Ral guanyl-nucleotide exchange factor activity","GO:0007264//small GTPase mediated signal transduction;GO:0019216//regulation of lipid metabolic process","K17635//ral guanine nucleotide dissociation stimulator-like 1","NP_001284599.1//ral guanine nucleotide dissociation stimulator-like 1 isoform 2 [Homo sapiens];XP_007987407.1//PREDICTED: ral guanine nucleotide dissociation stimulator-like 1 isoform X1 [Chlorocebus sabaeus];NP_055964.3//ral guanine nucleotide dissociation stimulator-like 1 isoform 1 [Homo sapiens]","4;1//3"]
[57731,8705,0.39,0.6,0.62148837674627,0.126887306989317,"*",0.061712,"SPTBN4","GO:0016020//membrane;GO:0043194//axon initial segment;GO:0005737//cytoplasm;GO:0043025//neuronal cell body;GO:0005829//cytosol;GO:0014704//intercalated disc;GO:0005886//plasma membrane;GO:0070062//extracellular exosome;GO:0016605//PML body;GO:0043203//axon hillock;GO:0070852//cell body fiber;GO:0016363//nuclear matrix;GO:0005912//adherens junction;GO:0033270//paranode region of axon;GO:0008091//spectrin;GO:0033268//node of Ranvier","GO:0003779//actin binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0019902//phosphatase binding;GO:0005200//structural constituent of cytoskeleton;GO:0030506//ankyrin binding;GO:0030507//spectrin binding;GO:0005543//phospholipid binding","GO:0002028//regulation of sodium ion transport;GO:0019226//transmission of nerve impulse;GO:0007016//cytoskeletal anchoring at plasma membrane;GO:0033135//regulation of peptidyl-serine phosphorylation;GO:0010459//negative regulation of heart rate;GO:0016192//vesicle-mediated transport;GO:0007411//axon guidance;GO:0051693//actin filament capping;GO:0061337//cardiac conduction;GO:0000165//MAPK cascade;GO:0009566//fertilization;GO:0072659//protein localization to plasma membrane;GO:0045162//clustering of voltage-gated sodium channels;GO:0007409//axonogenesis;GO:0007605//sensory perception of sound;GO:0007628//adult walking behavior;GO:0021952//central nervous system projection neuron axonogenesis;GO:0040018//positive regulation of multicellular organism growth;GO:0006888//ER to Golgi vesicle-mediated transport","K06115//spectrin beta","EAW56975.1//spectrin, beta, non-erythrocytic 4, isoform CRA_c [Homo sapiens];NP_066022.2//spectrin beta chain, non-erythrocytic 4 isoform sigma1 [Homo sapiens]","2//1"]
[4313,3152,1.84,2.83,0.621096286774869,0.0101940435549133,"*",3.53288E-3,"MMP2","GO:0031012//extracellular matrix;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0030017//sarcomere;GO:0005578//proteinaceous extracellular matrix;GO:0005576//extracellular region;GO:0005739//mitochondrion;GO:0005886//plasma membrane","GO:0004252//serine-type endopeptidase activity;GO:0008237//metallopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding","GO:0045089//positive regulation of innate immune response;GO:0035987//endodermal cell differentiation;GO:1904707//positive regulation of vascular smooth muscle cell proliferation;GO:0007566//embryo implantation;GO:0044267//cellular protein metabolic process;GO:0060346//bone trabecula formation;GO:0001525//angiogenesis;GO:0048013//ephrin receptor signaling pathway;GO:0001957//intramembranous ossification;GO:0001955//blood vessel maturation;GO:0071230//cellular response to amino acid stimulus;GO:0001666//response to hypoxia;GO:0022617//extracellular matrix disassembly;GO:0006508//proteolysis;GO:0060325//face morphogenesis;GO:0030574//collagen catabolic process","K01398//matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]","NP_001121363.1//72 kDa type IV collagenase isoform 2 [Homo sapiens];NP_004521.1//72 kDa type IV collagenase isoform 1 preproprotein [Homo sapiens]","1//3;2//1;5"]
[148327,1783,3.7,5.69,0.62090338179027,1.94385681014799E-3,"*",0.000575588,"CREB3L4","GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0005783//endoplasmic reticulum;GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005739//mitochondrion","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0035497//cAMP response element binding","GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007283//spermatogenesis;GO:0030968//endoplasmic reticulum unfolded protein response","K09048//cyclic AMP-responsive element-binding protein 3","NP_001242909.1//cyclic AMP-responsive element-binding protein 3-like protein 4 isoform 2 [Homo sapiens];NP_570968.1//cyclic AMP-responsive element-binding protein 3-like protein 4 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[84258,2493,0.67,1.03,0.620411336725446,0.37583767179178,"*",0.234128,"SYT3","GO:0030658//transport vesicle membrane;GO:0005768//endosome;GO:0098793//presynapse;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005544//calcium-dependent phospholipid binding;GO:0030276//clathrin binding;GO:0005509//calcium ion binding;GO:0019905//syntaxin binding","GO:0006906//vesicle fusion;GO:1903861//positive regulation of dendrite extension;GO:0048791//calcium ion-regulated exocytosis of neurotransmitter;GO:0017158//regulation of calcium ion-dependent exocytosis;GO:0017156//calcium ion regulated exocytosis","K19903//synaptotagmin-3","XP_018872170.1//PREDICTED: synaptotagmin-3 isoform X1 [Gorilla gorilla gorilla]","1//3;2//1"]
[27242,3646,23.16,35.6,0.620241987864524,{"v":4.0220240647541E-27,"d":"4.02E-27"},"*",{"v":1.228714E-28,"d":"1.23E-28"},"TNFRSF21","GO:0030424//axon;GO:0031226//intrinsic component of plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005031//tumor necrosis factor-activated receptor activity","GO:0048713//regulation of oligodendrocyte differentiation;GO:2001180//negative regulation of interleukin-10 secretion;GO:0051402//neuron apoptotic process;GO:0097190//apoptotic signaling pathway;GO:0042127//regulation of cell proliferation;GO:2000663//negative regulation of interleukin-5 secretion;GO:0032496//response to lipopolysaccharide;GO:0071356//cellular response to tumor necrosis factor;GO:0042130//negative regulation of T cell proliferation;GO:0006959//humoral immune response;GO:0019216//regulation of lipid metabolic process;GO:0097252//oligodendrocyte apoptotic process;GO:0031642//negative regulation of myelination;GO:0042552//myelination;GO:0001783//B cell apoptotic process;GO:0007165//signal transduction;GO:0050852//T cell receptor signaling pathway;GO:2000666//negative regulation of interleukin-13 secretion;GO:0002250//adaptive immune response;GO:0006915//apoptotic process;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0030889//negative regulation of B cell proliferation;GO:0042981//regulation of apoptotic process","K05157//tumor necrosis factor receptor superfamily member 21","XP_003128478.3//tumor necrosis factor receptor superfamily member 21 [Sus scrofa]",4]
[154467,637,19.45,29.83,0.616993822461658,0.000183895724380165,"*",{"v":4.45752E-5,"d":"4.46E-05"},"CCDC167","GO:0016021//integral component of membrane","NA","NA","NA","AAF28943.1//HSPC265, partial [Homo sapiens]","2//1"]
[56144,5170,0.6,0.92,0.616671360448494,0.116226464705113,"*",0.0556394,"PCDHA4","NA","NA","NA","K16493//protocadherin alpha","XP_017387687.1//PREDICTED: protocadherin alpha-4 [Cebus capucinus imitator];XP_012360376.1//PREDICTED: protocadherin alpha-4 isoform X12 [Nomascus leucogenys]","3//A2MP1;2//1"]
[6919,1273,6.68,10.24,0.616295707525948,0.0017872495601023,"*",0.000524964,"TCEA2","GO:0005634//nucleus;GO:0008023//transcription elongation factor complex","GO:0003677//DNA binding;GO:0003746//translation elongation factor activity;GO:0008270//zinc ion binding;GO:0003676//nucleic acid binding","GO:0032784//regulation of DNA-templated transcription, elongation;GO:0006355//regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006354//DNA-templated transcription, elongation;GO:0006351//transcription, DNA-templated","K03145//transcription elongation factor S-II","XP_008960554.1//PREDICTED: transcription elongation factor A protein 2 isoform X2 [Pan paniscus]","2//1;5"]
[116541,628,17.58,26.91,0.614207320497014,0.000490152706151645,"*",0.0001286904,"MRPL54","GO:0005762//mitochondrial large ribosomal subunit;GO:0005743//mitochondrial inner membrane","GO:0003723//RNA binding","GO:0070126//mitochondrial translational termination;GO:0070125//mitochondrial translational elongation","K17435//large subunit ribosomal protein L54","NP_758455.1//39S ribosomal protein L54, mitochondrial [Homo sapiens]","2//1"]
[63970,970,0.49,0.75,0.614108846380673,0.629047590254534,"*",0.505908,"TP53AIP1","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","NA","GO:0042981//regulation of apoptotic process;GO:0006915//apoptotic process","K13773//p53-regulated apoptosis-inducing protein 1","XP_011908764.1//PREDICTED: p53-regulated apoptosis-inducing protein 1 isoform X1 [Cercocebus atys];XP_016873606.1//PREDICTED: p53-regulated apoptosis-inducing protein 1 isoform X5 [Homo sapiens];XP_016873602.1//PREDICTED: p53-regulated apoptosis-inducing protein 1 isoform X1 [Homo sapiens];XP_016873603.1//PREDICTED: p53-regulated apoptosis-inducing protein 1 isoform X2 [Homo sapiens]","1//3;2//1"]
[56931,2127,12.14,18.58,0.613982080126971,{"v":1.23015471432734e-08,"d":"1.23E-08"},"*",{"v":1.585632e-09,"d":"1.59E-09"},"DUS3L","NA","GO:0003723//RNA binding;GO:0046872//metal ion binding;GO:0017150//tRNA dihydrouridine synthase activity;GO:0050660//flavin adenine dinucleotide binding","NA","K05544//tRNA-dihydrouridine synthase 3 [EC:1.3.1.89]","NP_064560.2//tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like isoform 1 [Homo sapiens];NP_001155091.1//tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like isoform 2 [Homo sapiens]","1//3;2//1"]
[161725,2411,0.17,0.26,0.612976876890753,0.718782444179815,"*",0.60458,"OTUD7A","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0070530//K63-linked polyubiquitin modification-dependent protein binding;GO:0004843//thiol-dependent ubiquitin-specific protease activity;GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0036459//thiol-dependent ubiquitinyl hydrolase activity","GO:0050727//regulation of inflammatory response;GO:0071108//protein K48-linked deubiquitination;GO:0071947//protein deubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination;GO:0006955//immune response;GO:0045088//regulation of innate immune response;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0070536//protein K63-linked deubiquitination;GO:0035871//protein K11-linked deubiquitination","K11860//OTU domain-containing protein 7 [EC:3.4.19.12]","NP_001316836.1//OTU domain-containing protein 7A isoform 2 [Homo sapiens];NP_570971.1//OTU domain-containing protein 7A isoform 1 [Homo sapiens]","1//3;2//1"]
[6273,970,2.89,4.42,0.612976876890753,0.109311861568886,"*",0.051905,"S100A2","NA","GO:0042802//identical protein binding;GO:0005509//calcium ion binding;GO:0046914//transition metal ion binding","GO:0043542//endothelial cell migration","K21128//protein S100-A9;K17274//calpactin-1 light chain","P29034.3//RecName: Full=Protein S100-A2; AltName: Full=CAN19; AltName: Full=Protein S-100L; AltName: Full=S100 calcium-binding protein A2","3//A2MP1"]
[4013,1874,0.17,0.26,0.612976876890753,0.666116652986498,"*",0.546646,"VWA5A","NA","NA","NA","K10798//poly [ADP-ribose] polymerase [EC:2.4.2.30]","XP_011541130.1//PREDICTED: von Willebrand factor A domain-containing protein 5A isoform X1 [Homo sapiens]","1//3;4;2//1"]
[27120,1018,0.17,0.26,0.612976876890753,0.780361083214591,"*",0.685686,"DKKL1","GO:0005615//extracellular space;GO:0001669//acrosomal vesicle","GO:0004871//signal transducer activity","GO:0043065//positive regulation of apoptotic process;GO:0009653//anatomical structure morphogenesis;GO:2000225//negative regulation of testosterone biosynthetic process;GO:0007341//penetration of zona pellucida;GO:0045600//positive regulation of fat cell differentiation","K13911//basic salivary proline-rich protein 1/2;K14398//cleavage and polyadenylation specificity factor subunit 6/7;K11448//lysine-specific demethylase 6B [EC:1.14.11.-]","XP_011525026.1//PREDICTED: dickkopf-like protein 1 isoform X1 [Homo sapiens];NP_001184230.1//dickkopf-like protein 1 isoform 2 precursor [Homo sapiens];NP_055234.1//dickkopf-like protein 1 isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[6909,3396,2.57,3.93,0.612760953064729,1.59876841411967E-3,"*",4.64998E-4,"TBX2","GO:0005634//nucleus;GO:0005667//transcription factor complex","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0003148//outflow tract septum morphogenesis;GO:0060596//mammary placode formation;GO:0048738//cardiac muscle tissue development;GO:0042733//embryonic digit morphogenesis;GO:0035909//aorta morphogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0060560//developmental growth involved in morphogenesis;GO:0007521//muscle cell fate determination;GO:0090398//cellular senescence;GO:0008016//regulation of heart contraction;GO:0003203//endocardial cushion morphogenesis;GO:0060021//palate development;GO:0048596//embryonic camera-type eye morphogenesis;GO:0003256//regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0007569//cell aging;GO:0006351//transcription, DNA-templated;GO:0035050//embryonic heart tube development;GO:1901211//negative regulation of cardiac chamber formation;GO:0003151//outflow tract morphogenesis;GO:0001947//heart looping;GO:0060465//pharynx development;GO:0007219//Notch signaling pathway;GO:1901208//negative regulation of heart looping;GO:0008284//positive regulation of cell proliferation;GO:0036302//atrioventricular canal development","K10176//T-box protein 2","NP_005985.3//T-box transcription factor TBX2 [Homo sapiens]","3//A2MP1"]
[3606,1160,26.54,40.58,0.612600494386466,{"v":5.91983120731011e-10,"d":"5.92E-10"},"*",{"v":6.48906e-11,"d":"6.49E-11"},"IL18","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005576//extracellular region","GO:0005125//cytokine activity","GO:0010744//positive regulation of macrophage derived foam cell differentiation;GO:0045630//positive regulation of T-helper 2 cell differentiation;GO:0042253//granulocyte macrophage colony-stimulating factor biosynthetic process;GO:0032740//positive regulation of interleukin-17 production;GO:0042231//interleukin-13 biosynthetic process;GO:0070328//triglyceride homeostasis;GO:0035744//T-helper 1 cell cytokine production;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0032729//positive regulation of interferon-gamma production;GO:0042104//positive regulation of activated T cell proliferation;GO:0001525//angiogenesis;GO:0042267//natural killer cell mediated cytotoxicity;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0035655//interleukin-18-mediated signaling pathway;GO:0032725//positive regulation of granulocyte macrophage colony-stimulating factor production;GO:0045662//negative regulation of myoblast differentiation;GO:0030101//natural killer cell activation;GO:0042033//chemokine biosynthetic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0032148//activation of protein kinase B activity;GO:0051897//positive regulation of protein kinase B signaling;GO:0042092//type 2 immune response;GO:0034105//positive regulation of tissue remodeling;GO:0050729//positive regulation of inflammatory response;GO:0032819//positive regulation of natural killer cell proliferation;GO:0042094//interleukin-2 biosynthetic process;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0071407//cellular response to organic cyclic compound;GO:0008283//cell proliferation;GO:0042088//T-helper 1 type immune response;GO:0042632//cholesterol homeostasis;GO:0030155//regulation of cell adhesion;GO:0000165//MAPK cascade;GO:0042119//neutrophil activation;GO:0007267//cell-cell signaling;GO:0032635//interleukin-6 production;GO:0006954//inflammatory response;GO:0042346//positive regulation of NF-kappaB import into nucleus;GO:0051142//positive regulation of NK T cell proliferation;GO:0042095//interferon-gamma biosynthetic process;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0030431//sleep;GO:0006955//immune response","K05482//interleukin 18","NP_001230140.1//interleukin-18 isoform 2 [Homo sapiens];NP_001553.1//interleukin-18 isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[3107,1586,29.73,45.44,0.612043371597038,{"v":8.68853304317181e-15,"d":"8.69E-15"},"*",{"v":6.17346e-16,"d":"6.17E-16"},"HLA-C","NA","NA","NA","K06751//major histocompatibility complex, class I","SBW38606.1//MHC class I antigen [Homo sapiens];ANJ45904.1//MHC class I antigen [Homo sapiens]","1//3;5"]
[137994,2495,3.37,5.15,0.611823840888722,0.00104804660106857,"*",0.000294718,"LETM2","GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion","GO:0043022//ribosome binding","GO:0006875//cellular metal ion homeostasis","K12581//CCR4-NOT transcription complex subunit 7/8;K11447//histone demethylase [EC:1.14.11.-];K17800//LETM1 and EF-hand domain-containing protein 1, mitochondrial","NP_001273750.1//LETM1 domain-containing protein LETM2, mitochondrial isoform 5 [Homo sapiens];EAW63318.1//leucine zipper-EF-hand containing transmembrane protein 2, isoform CRA_b, partial [Homo sapiens];NP_001273748.1//LETM1 domain-containing protein LETM2, mitochondrial isoform 4 [Homo sapiens];NP_001317444.1//LETM1 domain-containing protein LETM2, mitochondrial isoform 6 [Homo sapiens];XP_011542711.1//PREDICTED: LETM1 domain-containing protein LETM2, mitochondrial isoform X5 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[79058,1889,17.52,26.76,0.611075341040288,{"v":8.43568384343434e-11,"d":"8.44E-11"},"*",{"v":8.36492e-12,"d":"8.36E-12"},"ASPSCR1","GO:0043231//intracellular membrane-bounded organelle;GO:0005654//nucleoplasm;GO:0019898//extrinsic component of membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0048471//perinuclear region of cytoplasm;GO:0012505//endomembrane system;GO:0012506//vesicle membrane;GO:0005829//cytosol;GO:0009898//cytoplasmic side of plasma membrane;GO:0005886//plasma membrane","NA","GO:0006886//intracellular protein transport;GO:0031401//positive regulation of protein modification process;GO:0046324//regulation of glucose import;GO:0042593//glucose homeostasis","K15627//tether containing UBX domain for GLUT4","NP_076988.1//tether containing UBX domain for GLUT4 isoform 1 [Homo sapiens];NP_001238817.1//tether containing UBX domain for GLUT4 isoform 2 [Homo sapiens];XP_016880531.1//PREDICTED: tether containing UBX domain for GLUT4 isoform X6 [Homo sapiens]","1//3;3//A2MP1"]
[84174,2519,0.76,1.16,0.610053481683987,0.183461437569982,"*",0.0964166,"SLA2","GO:0043231//intracellular membrane-bounded organelle;GO:0010008//endosome membrane;GO:0005654//nucleoplasm;GO:0005770//late endosome;GO:0005737//cytoplasm;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane","GO:0005070//SH3/SH2 adaptor activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0047485//protein N-terminus binding;GO:0005102//receptor binding","GO:0042110//T cell activation;GO:0016477//cell migration;GO:0038083//peptidyl-tyrosine autophosphorylation;GO:0030154//cell differentiation;GO:0042127//regulation of cell proliferation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0030522//intracellular receptor signaling pathway;GO:0050869//negative regulation of B cell activation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0045087//innate immune response;GO:0050776//regulation of immune response;GO:0050851//antigen receptor-mediated signaling pathway;GO:0019724//B cell mediated immunity;GO:0050849//negative regulation of calcium-mediated signaling","K08890//B lymphoid tyrosine kinase [EC:2.7.10.2];K08893//hemopoietic cell kinase [EC:2.7.10.2]","NP_115590.1//src-like-adapter 2 isoform a [Homo sapiens];NP_778252.1//src-like-adapter 2 isoform b [Homo sapiens]","3//A2MP1;2//1"]
[5898,2828,11.16,17.02,0.608894009856775,{"v":3.20864854169131e-10,"d":"3.21E-10"},"*",{"v":3.39666e-11,"d":"3.40E-11"},"RALA","GO:0070062//extracellular exosome;GO:0005925//focal adhesion;GO:0005622//intracellular;GO:0043209//myelin sheath;GO:0030496//midbody;GO:0009986//cell surface;GO:0032154//cleavage furrow;GO:0030139//endocytic vesicle;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0030659//cytoplasmic vesicle membrane","GO:0004713//protein tyrosine kinase activity;GO:0019003//GDP binding;GO:0031625//ubiquitin protein ligase binding;GO:0017022//myosin binding;GO:0031755//Edg-2 lysophosphatidic acid receptor binding;GO:0005525//GTP binding;GO:0051117//ATPase binding;GO:0003924//GTPase activity","GO:0051665//membrane raft localization;GO:0031532//actin cytoskeleton reorganization;GO:0051491//positive regulation of filopodium assembly;GO:0061024//membrane organization;GO:0017157//regulation of exocytosis;GO:0051301//cell division;GO:0001843//neural tube closure;GO:0007049//cell cycle;GO:0007265//Ras protein signal transduction;GO:0006887//exocytosis","K07834//Ras-related protein Ral-A","XP_006143062.1//PREDICTED: ras-related protein Ral-A isoform X1 [Tupaia chinensis]","3//A2MP1"]
[6665,1394,1.22,1.86,0.608421473545145,0.235700079686626,"*",0.131838,"SOX15","GO:0005634//nucleus;GO:0044798//nuclear transcription factor complex;GO:0005737//cytoplasm","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0046982//protein heterodimerization activity;GO:0003700//DNA binding transcription factor activity","GO:0070318//positive regulation of G0 to G1 transition;GO:0043403//skeletal muscle tissue regeneration;GO:0030154//cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0045843//negative regulation of striated muscle tissue development;GO:2000288//positive regulation of myoblast proliferation;GO:0008584//male gonad development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0014718//positive regulation of satellite cell activation involved in skeletal muscle regeneration;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006325//chromatin organization;GO:0048627//myoblast development","K09271//transcription factor SOX15/30","NP_008873.1//protein SOX-15 [Homo sapiens]","1//3"]
[7076,931,189.14,288.36,0.608416552467734,{"v":1.92417183518519e-51,"d":"1.92E-51"},"*",{"v":2.60186E-53,"d":"2.60E-53"},"TIMP1","GO:0031093//platelet alpha granule lumen;GO:0070062//extracellular exosome;GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005578//proteinaceous extracellular matrix;GO:0005604//basement membrane","GO:0002020//protease binding;GO:0046872//metal ion binding;GO:0008083//growth factor activity;GO:0008191//metalloendopeptidase inhibitor activity;GO:0005125//cytokine activity;GO:0008270//zinc ion binding","GO:0043687//post-translational protein modification;GO:0010951//negative regulation of endopeptidase activity;GO:0034097//response to cytokine;GO:0051216//cartilage development;GO:0044267//cellular protein metabolic process;GO:0002576//platelet degranulation;GO:1905049//negative regulation of metallopeptidase activity;GO:1901164//negative regulation of trophoblast cell migration;GO:0043086//negative regulation of catalytic activity;GO:2001044//regulation of integrin-mediated signaling pathway;GO:0042060//wound healing;GO:0043434//response to peptide hormone;GO:0043066//negative regulation of apoptotic process;GO:0007568//aging;GO:0022617//extracellular matrix disassembly;GO:0001775//cell activation;GO:0009725//response to hormone;GO:0051045//negative regulation of membrane protein ectodomain proteolysis;GO:0008284//positive regulation of cell proliferation","K16451//metallopeptidase inhibitor 1","XP_012603832.1//metalloproteinase inhibitor 1 [Microcebus murinus]","2//1"]
[7286,3109,7,10.67,0.608133348992096,{"v":2.43927261690722e-07,"d":"2.44E-07"},"*",{"v":3.70304e-08,"d":"3.70E-08"},"TUFT1","GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0030345//structural constituent of tooth enamel","GO:0030282//bone mineralization;GO:0042476//odontogenesis","K22031//myocardial zonula adherens protein","NP_001288246.1//tuftelin isoform 3 [Homo sapiens];NP_001119809.1//tuftelin isoform 2 [Homo sapiens];NP_064512.1//tuftelin isoform 1 [Homo sapiens]","1//3;2//1"]
[94115,904,6.07,9.25,0.607756849147992,0.0175916956124005,"*",0.0065008,"CGB8","GO:0005576//extracellular region","GO:0005179//hormone activity","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0016486//peptide hormone processing;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0007292//female gamete generation;GO:0006915//apoptotic process","K10045//chorionic gonadotropin, beta polypeptide","Q6NT52.4//RecName: Full=Choriogonadotropin subunit beta variant 2; Flags: Precursor","2//1"]
[83638,1569,45.82,69.8,0.607249577792339,{"v":1.04068168558952e-21,"d":"1.04E-21"},"*",{"v":4.4757e-23,"d":"4.48E-23"},"C11orf68","NA","GO:0003723//RNA binding","NA","NA","NP_113638.2//UPF0696 protein C11orf68 isoform 2 [Homo sapiens];NP_001129107.1//UPF0696 protein C11orf68 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[4188,1728,0.23,0.35,0.605721060887954,0.695530726766499,"*",0.578622,"MDFI","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0042802//identical protein binding;GO:0008134//transcription factor binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0042994//cytoplasmic sequestering of transcription factor;GO:0030178//negative regulation of Wnt signaling pathway;GO:0060707//trophoblast giant cell differentiation;GO:0009950//dorsal/ventral axis specification;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0043392//negative regulation of DNA binding;GO:0048704//embryonic skeletal system morphogenesis;GO:0009790//embryo development","NA","NP_001287734.1//myoD family inhibitor isoform 2 [Homo sapiens];NP_005577.1//myoD family inhibitor isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[646915,2891,0.23,0.35,0.605721060887954,0.534720454209879,"*",0.380872,"ZNF806","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","NP_001342390.1//zinc finger protein 806 isoform 2 [Homo sapiens];XP_017715274.1//PREDICTED: zinc finger protein 285 isoform X1 [Rhinopithecus bieti]","1//3"]
[5691,809,190.75,290.13,0.605016423631182,{"v":3.11358867175573E-44,"d":"3.11E-44"},"*",{"v":5.1068e-46,"d":"5.11E-46"},"PSMB3","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0019774//proteasome core complex, beta-subunit complex;GO:0005737//cytoplasm","GO:0004298//threonine-type endopeptidase activity","GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process","K02735//20S proteasome subunit beta 3 [EC:3.4.25.1]","XP_004454988.1//PREDICTED: proteasome subunit beta type-3 [Dasypus novemcinctus]","3//A2MP1"]
[79012,3245,0.25,0.38,0.604071323668861,0.39095887689243,"*",0.245726,"CAMKV","GO:0005622//intracellular;GO:0005886//plasma membrane;GO:0030659//cytoplasmic vesicle membrane","GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0004683//calmodulin-dependent protein kinase activity;GO:0005516//calmodulin binding","GO:0018107//peptidyl-threonine phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0035556//intracellular signal transduction","K08812//CaM kinase-like vesicle-associated [EC:2.7.11.-]","NP_076951.2//caM kinase-like vesicle-associated protein isoform 1 [Homo sapiens];NP_001307076.1//caM kinase-like vesicle-associated protein isoform 2 [Homo sapiens]","1//3;4"]
[3929,1894,0.25,0.38,0.604071323668861,0.608665132647902,"*",0.452136,"LBP","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0009986//cell surface;GO:0005576//extracellular region","GO:0001530//lipopolysaccharide binding;GO:0071723//lipopeptide binding;GO:0005102//receptor binding;GO:0070891//lipoteichoic acid binding","GO:0002232//leukocyte chemotaxis involved in inflammatory response;GO:0032755//positive regulation of interleukin-6 production;GO:0050829//defense response to Gram-negative bacterium;GO:0071222//cellular response to lipopolysaccharide;GO:0032496//response to lipopolysaccharide;GO:0032720//negative regulation of tumor necrosis factor production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0002281//macrophage activation involved in immune response;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0050830//defense response to Gram-positive bacterium;GO:0045087//innate immune response;GO:0034142//toll-like receptor 4 signaling pathway;GO:0008228//opsonization;GO:0045919//positive regulation of cytolysis;GO:0090023//positive regulation of neutrophil chemotaxis;GO:0043032//positive regulation of macrophage activation;GO:0032490//detection of molecule of bacterial origin;GO:0032757//positive regulation of interleukin-8 production;GO:0006953//acute-phase response;GO:0071223//cellular response to lipoteichoic acid;GO:0002224//toll-like receptor signaling pathway;GO:0006968//cellular defense response;GO:0042535//positive regulation of tumor necrosis factor biosynthetic process;GO:0060265//positive regulation of respiratory burst involved in inflammatory response;GO:0044130//negative regulation of growth of symbiont in host;GO:0015920//lipopolysaccharide transport;GO:0033036//macromolecule localization;GO:0032722//positive regulation of chemokine production;GO:0034145//positive regulation of toll-like receptor 4 signaling pathway","K05399//lipopolysaccharide-binding protein","NP_004130.2//lipopolysaccharide-binding protein precursor [Homo sapiens]",4]
[26052,4505,0.27,0.41,0.602664502454615,0.639211267489031,"*",0.48335,"DNM3","GO:0070062//extracellular exosome;GO:0030424//axon;GO:0001917//photoreceptor inner segment;GO:0005874//microtubule;GO:0014069//postsynaptic density;GO:0048471//perinuclear region of cytoplasm;GO:0044327//dendritic spine head;GO:0098844//postsynaptic endocytic zone membrane;GO:0005794//Golgi apparatus;GO:0005739//mitochondrion;GO:0043197//dendritic spine;GO:0031966//mitochondrial membrane;GO:0045202//synapse;GO:0043083//synaptic cleft","GO:0050998//nitric-oxide synthase binding;GO:0031798//type 1 metabotropic glutamate receptor binding;GO:0042802//identical protein binding;GO:0031802//type 5 metabotropic glutamate receptor binding;GO:0005525//GTP binding;GO:0008017//microtubule binding;GO:0003924//GTPase activity","GO:0051491//positive regulation of filopodium assembly;GO:0046847//filopodium assembly;GO:0016185//synaptic vesicle budding from presynaptic endocytic zone membrane;GO:0007416//synapse assembly;GO:0003374//dynamin family protein polymerization involved in mitochondrial fission;GO:0061025//membrane fusion;GO:0006897//endocytosis;GO:0061002//negative regulation of dendritic spine morphogenesis;GO:0098884//postsynaptic neurotransmitter receptor internalization;GO:0000266//mitochondrial fission","K01528//dynamin GTPase [EC:3.6.5.5]","XP_010369589.1//PREDICTED: dynamin-3 isoform X1 [Rhinopithecus roxellana];NP_001337133.1//dynamin-3 isoform d [Homo sapiens];NP_001337134.1//dynamin-3 isoform e [Homo sapiens];NP_001337135.1//dynamin-3 isoform f [Homo sapiens];NP_056384.2//dynamin-3 isoform a [Homo sapiens];XP_018882231.1//PREDICTED: dynamin-3 isoform X6 [Gorilla gorilla gorilla]","4;1//3;2//1"]
[94032,1360,3.11,4.72,0.601872279231239,0.043049316263372,"*",0.01788646,"CAMK2N2","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005813//centrosome","GO:0004860//protein kinase inhibitor activity;GO:0016301//kinase activity;GO:0008427//calcium-dependent protein kinase inhibitor activity;GO:0019901//protein kinase binding","GO:0048167//regulation of synaptic plasticity","K00894//ethanolamine kinase [EC:2.7.1.82];K19475//WAS/WASL-interacting protein;K13171//serine/arginine repetitive matrix protein 1","XP_016284939.1//PREDICTED: calcium/calmodulin-dependent protein kinase II inhibitor 2 [Monodelphis domestica]","2//1"]
[147798,2477,0.87,1.32,0.601450623509725,0.172653231392405,"*",0.0896556,"TMC4","GO:0070062//extracellular exosome;GO:0016021//integral component of membrane","NA","GO:0006811//ion transport","K21988//transmembrane channel-like protein","NP_653287.2//transmembrane channel-like protein 4 isoform 2 [Homo sapiens];NP_001138775.2//transmembrane channel-like protein 4 isoform 1 [Homo sapiens]","3//A2MP1;2//1"]
[25900,2707,0.29,0.44,0.601450623509725,0.475850106306803,"*",0.324492,"IFFO1","GO:0005882//intermediate filament","GO:0005198//structural molecule activity","NA","K07605//type II keratin, basic;K07607//peripherin;K07608//internexin neuronal intermediate filament protein, alpha;K07606//vimentin","NP_001317254.1//intermediate filament family orphan 1 isoform 8 [Homo sapiens];NP_542768.2//intermediate filament family orphan 1 isoform 2 [Homo sapiens];NP_001180386.1//intermediate filament family orphan 1 isoform 5 [Homo sapiens];NP_001034759.1//intermediate filament family orphan 1 isoform 4 [Homo sapiens];NP_001317253.1//intermediate filament family orphan 1 isoform 7 [Homo sapiens]","4;1//3;2//1"]
[90187,3827,0.89,1.35,0.601082166084433,0.0754236426853147,"*",0.0337598,"EMILIN3","GO:0031012//extracellular matrix;GO:0005737//cytoplasm;GO:0005578//proteinaceous extracellular matrix","NA","NA","K16628//collagen, type VII, alpha","EAW75984.1//elastin microfibril interfacer 3, isoform CRA_b [Homo sapiens]","1//3"]
[730005,3394,0.62,0.94,0.600392541290762,0.156816184013689,"*",0.0803224,"SEC14L6","GO:0005622//intracellular;GO:0016021//integral component of membrane","GO:0005215//transporter activity","NA","K01019//galactosylceramide sulfotransferase [EC:2.8.2.11];K17985//activating molecule in BECN1-regulated autophagy protein 1;K17981//mitochondrial fission process protein 1","XP_015005508.1//PREDICTED: LOW QUALITY PROTEIN: putative SEC14-like protein 6 [Macaca mulatta];XP_016884422.1//PREDICTED: putative SEC14-like protein 6 isoform X6 [Homo sapiens]","1//3;3//A2MP1"]
[9976,2052,0.31,0.47,0.600392541290762,0.534673462342912,"*",0.380872,"CLEC2B","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0030246//carbohydrate binding;GO:0042802//identical protein binding","GO:0050776//regulation of immune response","K10071//C-type lectin domain family 2 member B","NP_005118.2//C-type lectin domain family 2 member B [Homo sapiens]","2//1"]
[4713,573,81.61,123.73,0.600377496174123,{"v":2.22404697224425e-13,"d":"2.22E-13"},"*",{"v":1.75568e-14,"d":"1.76E-14"},"NDUFB7","GO:0005747//mitochondrial respiratory chain complex I;GO:0005758//mitochondrial intermembrane space;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0008137//NADH dehydrogenase (ubiquinone) activity","GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0006120//mitochondrial electron transport, NADH to ubiquinone","K03963//NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 7","NP_004137.2//NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 [Homo sapiens]",5]
[91544,1598,9.03,13.69,0.600324553777042,{"v":7.04764339181287e-05,"d":"7.05E-05"},"*",{"v":1.58433e-05,"d":"1.58E-05"},"UBXN11","GO:0005856//cytoskeleton;GO:0005737//cytoplasm","GO:0043130//ubiquitin binding","GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process","K10592//E3 ubiquitin-protein ligase HUWE1 [EC:2.3.2.26]","NP_892120.2//UBX domain-containing protein 11 isoform 2 [Homo sapiens];NP_663320.2//UBX domain-containing protein 11 isoform 1 [Homo sapiens];NP_001070730.1//UBX domain-containing protein 11 isoform 3 [Homo sapiens]","1//3;2//1"]
[64773,1942,32.38,49.07,0.599738285765661,{"v":3.89166349378531e-18,"d":"3.89E-18"},"*",{"v":2.15608E-19,"d":"2.16E-19"},"PCED1A","NA","NA","NA","K05748//WAS protein family, member 2;K02184//formin 2","NP_073597.2//PC-esterase domain-containing protein 1A isoform 1 [Homo sapiens];NP_001258097.1//PC-esterase domain-containing protein 1A isoform 2 [Homo sapiens]","4;1//3"]
[375791,1314,0.99,1.5,0.599462070416271,0.344500432644628,"*",0.208762,"CYSRT1","GO:0070062//extracellular exosome","NA","NA","K13909//mucin-7;K21125//mucin-5AC","NP_945352.3//cysteine-rich tail protein 1 [Homo sapiens]","3//A2MP1"]
[11117,3959,0.66,1,0.599462070416271,0.126883428644962,"*",0.061726,"EMILIN1","NA","NA","NA","K16628//collagen, type VII, alpha","XP_003941621.1//PREDICTED: EMILIN-1 [Saimiri boliviensis boliviensis]","3//A2MP1"]
[6775,2827,4.49,6.8,0.598819301396555,1.40938728443272E-4,"*",{"v":3.34392e-05,"d":"3.34E-05"},"STAT4","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0042802//identical protein binding;GO:0004871//signal transducer activity;GO:0003700//DNA binding transcription factor activity","GO:0007259//JAK-STAT cascade;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0019221//cytokine-mediated signaling pathway;GO:0006351//transcription, DNA-templated;GO:0035722//interleukin-12-mediated signaling pathway","K11222//signal transducer and activator of transcription 4","XP_016805721.1//PREDICTED: signal transducer and activator of transcription 4 isoform X3 [Pan troglodytes];XP_008948871.1//PREDICTED: signal transducer and activator of transcription 4 isoform X1 [Pan paniscus]","1//3;3//A2MP1"]
[246329,1601,0.35,0.53,0.598637437618233,0.634211044676964,"*",0.4781,"STAC3","GO:0005654//nucleoplasm;GO:0005829//cytosol","GO:0046872//metal ion binding;GO:0042802//identical protein binding","GO:0035556//intracellular signal transduction;GO:0048741//skeletal muscle fiber development;GO:0003009//skeletal muscle contraction;GO:0007274//neuromuscular synaptic transmission","K04705//signal transducing adaptor molecule;K07366//GRB2-related adaptor protein 2","NP_001273185.1//SH3 and cysteine-rich domain-containing protein 3 isoform b [Homo sapiens];NP_659501.1//SH3 and cysteine-rich domain-containing protein 3 isoform a [Homo sapiens]","1//3;2//1"]
[10455,1418,24.97,37.8,0.598190413180223,{"v":8.50365055899054e-11,"d":"8.50E-11"},"*",{"v":8.43764E-12,"d":"8.44E-12"},"ECI2","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005654//nucleoplasm;GO:0005782//peroxisomal matrix;GO:0005777//peroxisome;GO:0005739//mitochondrion","GO:0005102//receptor binding;GO:0000062//fatty-acyl-CoA binding;GO:0004165//dodecenoyl-CoA delta-isomerase activity","GO:0033540//fatty acid beta-oxidation using acyl-CoA oxidase;GO:0009062//fatty acid catabolic process","K13239//peroxisomal 3,2-trans-enoyl-CoA isomerase [EC:5.3.3.8]","NP_996667.2//enoyl-CoA delta isomerase 2, mitochondrial isoform 2 [Homo sapiens]","1//3;2//1"]
[5549,5827,0.8,1.21,0.596935142387232,0.0331499104458001,"*",0.01326702,"PRELP","GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:1903561//extracellular vesicle;GO:0005578//proteinaceous extracellular matrix;GO:0005796//Golgi lumen;GO:0005576//extracellular region;GO:0043202//lysosomal lumen","GO:0005201//extracellular matrix structural constituent;GO:0008201//heparin binding","GO:0018146//keratan sulfate biosynthetic process;GO:0042340//keratan sulfate catabolic process;GO:0007569//cell aging;GO:0001501//skeletal system development","K08125//proline arginine-rich end leucine-rich repeat protein","NP_002716.1//prolargin precursor [Homo sapiens]","1//3;3//A2MP1"]
[4929,3546,1.23,1.86,0.596644305768792,0.040523372837407,"*",0.01671012,"NR4A2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016607//nuclear speck;GO:0005737//cytoplasm","GO:0003707//steroid hormone receptor activity;GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0035259//glucocorticoid receptor binding;GO:0042803//protein homodimerization activity;GO:0004879//nuclear receptor activity;GO:0046965//retinoid X receptor binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0008270//zinc ion binding;GO:0008013//beta-catenin binding","GO:0071376//cellular response to corticotropin-releasing hormone stimulus;GO:0008344//adult locomotory behavior;GO:0042053//regulation of dopamine metabolic process;GO:0042416//dopamine biosynthetic process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0009791//post-embryonic development;GO:0043085//positive regulation of catalytic activity;GO:2001234//negative regulation of apoptotic signaling pathway;GO:0031668//cellular response to extracellular stimulus;GO:0051866//general adaptation syndrome;GO:1904948//midbrain dopaminergic neuron differentiation;GO:0007165//signal transduction;GO:0043524//negative regulation of neuron apoptotic process;GO:0006351//transcription, DNA-templated;GO:0071542//dopaminergic neuron differentiation;GO:0021986//habenula development;GO:0001666//response to hypoxia;GO:0001975//response to amphetamine;GO:0060070//canonical Wnt signaling pathway;GO:0001764//neuron migration;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045444//fat cell differentiation;GO:0034599//cellular response to oxidative stress;GO:0021952//central nervous system projection neuron axonogenesis;GO:0043576//regulation of respiratory gaseous exchange;GO:0042551//neuron maturation;GO:0006367//transcription initiation from RNA polymerase II promoter","K08558//nuclear receptor subfamily 4 group A member 2","NP_006177.1//nuclear receptor subfamily 4 group A member 2 [Homo sapiens]","3//A2MP1"]
[131601,3817,21.86,33.04,0.595920285747541,{"v":1.49535103817863e-24,"d":"1.50E-24"},"*",{"v":5.34522e-26,"d":"5.35E-26"},"TPRA1","GO:0016021//integral component of membrane","GO:0004930//G-protein coupled receptor activity","GO:0040016//embryonic cleavage;GO:1901991//negative regulation of mitotic cell cycle phase transition;GO:0006629//lipid metabolic process;GO:0007568//aging","NA","NP_001339936.1//transmembrane protein adipocyte-associated 1 isoform 4 [Homo sapiens];EAW79340.1//G protein-coupled receptor 175, isoform CRA_a [Homo sapiens];NP_001339935.1//transmembrane protein adipocyte-associated 1 isoform 3 [Homo sapiens];EAW79341.1//G protein-coupled receptor 175, isoform CRA_b, partial [Homo sapiens]","1//3;3//A2MP1"]
[27,11776,3.5,5.29,0.595912800281697,{"v":7.89988667978804e-13,"d":"7.90E-13"},"*",{"v":6.53296e-14,"d":"6.53E-14"},"ABL2","GO:0005623//cell;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0005829//cytosol;GO:0015629//actin cytoskeleton","GO:0000287//magnesium ion binding;GO:0051015//actin filament binding;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005524//ATP binding;GO:0005102//receptor binding;GO:0003785//actin monomer binding;GO:0004713//protein tyrosine kinase activity;GO:0001784//phosphotyrosine residue binding;GO:0004672//protein kinase activity;GO:0030145//manganese ion binding","GO:0038083//peptidyl-tyrosine autophosphorylation;GO:0030100//regulation of endocytosis;GO:0042127//regulation of cell proliferation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0051353//positive regulation of oxidoreductase activity;GO:0010506//regulation of autophagy;GO:0030155//regulation of cell adhesion;GO:0045087//innate immune response;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030154//cell differentiation;GO:0007165//signal transduction;GO:0010976//positive regulation of neuron projection development;GO:2000145//regulation of cell motility;GO:0010863//positive regulation of phospholipase C activity;GO:2000249//regulation of actin cytoskeleton reorganization;GO:0071300//cellular response to retinoic acid;GO:0007155//cell adhesion;GO:0006464//cellular protein modification process;GO:0007204//positive regulation of cytosolic calcium ion concentration","K08887//abelson tyrosine-protein kinase 2 [EC:2.7.10.2]","NP_001161710.1//Abelson tyrosine-protein kinase 2 isoform h [Homo sapiens];NP_009298.1//Abelson tyrosine-protein kinase 2 isoform b [Homo sapiens];NP_001161709.1//Abelson tyrosine-protein kinase 2 isoform g [Homo sapiens];NP_001129473.1//Abelson tyrosine-protein kinase 2 isoform e [Homo sapiens];NP_005149.4//Abelson tyrosine-protein kinase 2 isoform c [Homo sapiens];CAD98092.1//hypothetical protein, partial [Homo sapiens];NP_001161708.1//Abelson tyrosine-protein kinase 2 isoform f [Homo sapiens]","4;1//3;3//A2MP1;2//1"]
[57169,7371,9.86,14.9,0.595652778971613,{"v":1.06254497267442E-21,"d":"1.06E-21"},"*",{"v":4.57638e-23,"d":"4.58E-23"},"ZNFX1","GO:0005634//nucleus","GO:0003723//RNA binding;GO:0008270//zinc ion binding;GO:0003700//DNA binding transcription factor activity","NA","K14326//regulator of nonsense transcripts 1 [EC:3.6.4.-]","NP_066363.1//NFX1-type zinc finger-containing protein 1 [Homo sapiens]","2//1"]
[151963,3388,1.88,2.84,0.595158267827045,0.0104825672655266,"*",3.64534E-3,"MB21D2","NA","GO:0032403//protein complex binding;GO:0045296//cadherin binding","NA","K04358//fibroblast growth factor","XP_021083798.1//protein MB21D2 [Mesocricetus auratus]","3//A2MP1"]
[147968,3129,27.77,41.95,0.59514363350834,{"v":1.9281956603352E-25,"d":"1.93E-25"},"*",{"v":6.48204e-27,"d":"6.48E-27"},"CAPN12","GO:0005737//cytoplasm","GO:0004198//calcium-dependent cysteine-type endopeptidase activity;GO:0005509//calcium ion binding","GO:0006508//proteolysis","K04740//calpain-12 [EC:3.4.22.-]","NP_653292.2//calpain-12 [Homo sapiens]",4]
[5271,3309,2.84,4.29,0.595086717994864,0.00285121076075872,"*",0.00087514,"SERPINB8","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0004867//serine-type endopeptidase inhibitor activity","GO:0090136//epithelial cell-cell adhesion;GO:0010951//negative regulation of endopeptidase activity","K13965//serpin B8","NP_001335296.1//serpin B8 isoform d [Homo sapiens];NP_001335297.1//serpin B8 isoform e [Homo sapiens];NP_001335299.1//serpin B8 isoform f [Homo sapiens];NP_942130.1//serpin B8 isoform a [Homo sapiens]","1//3;3//A2MP1"]
[84808,3089,0.96,1.45,0.594946589293778,0.0850239376323388,"*",0.0387116,"PERM1","GO:0005634//nucleus;GO:0005737//cytoplasm","NA","GO:0014850//response to muscle activity;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K14282//transforming acidic coiled-coil-containing protein 2;K16882//protein piccolo","NP_001278296.1//PGC-1 and ERR-induced regulator in muscle protein 1 isoform 2 [Homo sapiens];NP_001278295.1//PGC-1 and ERR-induced regulator in muscle protein 1 isoform 1 [Homo sapiens]","1//3"]
[124976,3459,0.96,1.45,0.594946589293778,0.087094316807871,"*",0.0398996,"SPNS2","GO:0005765//lysosomal membrane;GO:0016021//integral component of membrane;GO:0031982//vesicle","GO:0046624//sphingolipid transporter activity","GO:0003376//sphingosine-1-phosphate signaling pathway;GO:0060348//bone development;GO:0055085//transmembrane transport;GO:0048535//lymph node development;GO:0002920//regulation of humoral immune response;GO:0043029//T cell homeostasis;GO:0006665//sphingolipid metabolic process;GO:0040011//locomotion;GO:0001782//B cell homeostasis;GO:0072676//lymphocyte migration;GO:0048073//regulation of eye pigmentation","K20225//capicua transcriptional repressor;K14156//choline/ethanolamine kinase [EC:2.7.1.32 2.7.1.82];K19720//collagen, type III, alpha","AAH11467.1//Spns2 protein, partial [Mus musculus]","2//1"]
[7262,937,58.56,88.44,0.594783471532183,{"v":8.84783795066414e-16,"d":"8.85E-16"},"*",{"v":5.838e-17,"d":"5.84E-17"},"PHLDA2","GO:0016020//membrane;GO:0005737//cytoplasm","NA","GO:0010468//regulation of gene expression;GO:0001890//placenta development;GO:1903547//regulation of growth hormone activity;GO:0070873//regulation of glycogen metabolic process;GO:0060721//regulation of spongiotrophoblast cell proliferation;GO:0006915//apoptotic process;GO:0009887//animal organ morphogenesis;GO:0030334//regulation of cell migration","K03006//DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6];K17298//mucin-13","NP_003302.1//pleckstrin homology-like domain family A member 2 [Homo sapiens]","3//A2MP1"]
[4783,2102,6.49,9.8,0.594563271003432,1.21739415046854E-4,"*",{"v":2.84648e-05,"d":"2.85E-05"},"NFIL3","GO:0005634//nucleus","GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007623//circadian rhythm;GO:0006355//regulation of transcription, DNA-templated;GO:0006955//immune response;GO:0071353//cellular response to interleukin-4;GO:0010628//positive regulation of gene expression;GO:0006366//transcription from RNA polymerase II promoter","K09059//nuclear factor, interleukin 3 regulated","NP_005375.2//nuclear factor interleukin-3-regulated protein [Homo sapiens]","1//3;2//1"]
[4987,3331,0.61,0.92,0.592824618494127,0.239095377390527,"*",0.1339916,"OPRL1","GO:0005887//integral component of plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0043005//neuron projection","GO:0008022//protein C-terminus binding;GO:0042923//neuropeptide binding;GO:0001626//nociceptin receptor activity;GO:0004930//G-protein coupled receptor activity","GO:0007600//sensory perception;GO:0044849//estrous cycle;GO:0045776//negative regulation of blood pressure;GO:0032355//response to estradiol;GO:0019233//sensory perception of pain;GO:0001934//positive regulation of protein phosphorylation;GO:0007218//neuropeptide signaling pathway;GO:0060454//positive regulation of gastric acid secretion;GO:0030818//negative regulation of cAMP biosynthetic process;GO:1904059//regulation of locomotor rhythm;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:1904058//positive regulation of sensory perception of pain;GO:0042755//eating behavior;GO:1901386//negative regulation of voltage-gated calcium channel activity;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007268//chemical synaptic transmission;GO:0035810//positive regulation of urine volume","K04216//nociceptin receptor","NP_001305782.1//nociceptin receptor isoform 1x [Homo sapiens];NP_001305784.1//nociceptin receptor isoform 3 [Homo sapiens]","1//3;3//A2MP1;5"]
[6282,595,1037.94,1563.49,0.591046943382107,{"v":2.99577848181818e-163,"d":"3.00E-163"},"*",{"v":8.2518e-166,"d":"8.25E-166"},"S100A11","GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0001726//ruffle;GO:0005913//cell-cell adherens junction;GO:0005576//extracellular region","GO:0098641//cadherin binding involved in cell-cell adhesion;GO:0044548//S100 protein binding;GO:0005509//calcium ion binding;GO:0048306//calcium-dependent protein binding;GO:0042803//protein homodimerization activity","GO:0007165//signal transduction;GO:0042127//regulation of cell proliferation;GO:0043312//neutrophil degranulation;GO:0008156//negative regulation of DNA replication;GO:0008285//negative regulation of cell proliferation","K17274//calpactin-1 light chain","XP_010340417.1//PREDICTED: uncharacterized protein LOC101045489 [Saimiri boliviensis boliviensis]","1//3"]
[129303,1556,9.25,13.93,0.590669987197578,{"v":7.84897651837524e-05,"d":"7.85E-05"},"*",{"v":1.77823e-05,"d":"1.78E-05"},"TMEM150A","NA","NA","NA","K21846//transmembrane protein 150","XP_007120732.1//PREDICTED: transmembrane protein 150A [Physeter catodon]","2//1"]
[268,1883,10.12,15.24,0.590653612799012,{"v":3.89436432115782E-6,"d":"3.89E-06"},"*",{"v":7.0749e-07,"d":"7.07E-07"},"AMH","GO:0005615//extracellular space;GO:0005576//extracellular region","GO:0008083//growth factor activity;GO:0005102//receptor binding;GO:0005160//transforming growth factor beta receptor binding;GO:0005179//hormone activity","GO:0014070//response to organic cyclic compound;GO:0042493//response to drug;GO:0001655//urogenital system development;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0007267//cell-cell signaling;GO:0007530//sex determination;GO:0030509//BMP signaling pathway;GO:0010628//positive regulation of gene expression;GO:0007568//aging;GO:0008406//gonad development;GO:0007548//sex differentiation;GO:2000355//negative regulation of ovarian follicle development;GO:0001880//Mullerian duct regression;GO:0007506//gonadal mesoderm development;GO:0001546//preantral ovarian follicle growth","K04665//anti-mullerian hormone","NP_000470.2//muellerian-inhibiting factor preproprotein [Homo sapiens]",4]
[60490,2268,5.35,8.04,0.587656609890419,0.000376611778156997,"*",{"v":9.6711e-05,"d":"9.67E-05"},"PPCDC","GO:0005829//cytosol","GO:0042802//identical protein binding;GO:0003824//catalytic activity;GO:0004633//phosphopantothenoylcysteine decarboxylase activity","GO:0009108//coenzyme biosynthetic process;GO:0015937//coenzyme A biosynthetic process","K01598//phosphopantothenoylcysteine decarboxylase [EC:4.1.1.36]","XP_011946188.1//PREDICTED: phosphopantothenoylcysteine decarboxylase isoform X3 [Cercocebus atys];NP_068595.3//phosphopantothenoylcysteine decarboxylase isoform a [Homo sapiens];XP_011946186.1//PREDICTED: phosphopantothenoylcysteine decarboxylase isoform X1 [Cercocebus atys]","4;1//3"]
[718,5148,5.9,8.86,0.586591744305815,{"v":2.98261133087071E-9,"d":"2.98E-09"},"*",{"v":3.53828e-10,"d":"3.54E-10"},"C3","GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome;GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0072562//blood microparticle;GO:0035578//azurophil granule lumen;GO:0043234//protein complex;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0004252//serine-type endopeptidase activity;GO:0005102//receptor binding;GO:0004866//endopeptidase inhibitor activity;GO:0031715//C5L2 anaphylatoxin chemotactic receptor binding","GO:0043687//post-translational protein modification;GO:0030449//regulation of complement activation;GO:0006911//phagocytosis, engulfment;GO:0010575//positive regulation of vascular endothelial growth factor production;GO:0097242//amyloid-beta clearance;GO:0010884//positive regulation of lipid storage;GO:0010828//positive regulation of glucose transport;GO:0050766//positive regulation of phagocytosis;GO:0044267//cellular protein metabolic process;GO:0001970//positive regulation of activation of membrane attack complex;GO:2000427//positive regulation of apoptotic cell clearance;GO:0006631//fatty acid metabolic process;GO:0001934//positive regulation of protein phosphorylation;GO:0043312//neutrophil degranulation;GO:0045766//positive regulation of angiogenesis;GO:0050776//regulation of immune response;GO:0007186//G-protein coupled receptor signaling pathway;GO:0006956//complement activation;GO:0007165//signal transduction;GO:0006957//complement activation, alternative pathway;GO:0006954//inflammatory response;GO:0006958//complement activation, classical pathway;GO:0045745//positive regulation of G-protein coupled receptor protein signaling pathway;GO:0001798//positive regulation of type IIa hypersensitivity;GO:0010866//regulation of triglyceride biosynthetic process;GO:0006955//immune response","K03990//complement component 3","NP_000055.2//complement C3 preproprotein [Homo sapiens]","3//A2MP1"]
[102800317,2997,1.44,2.16,0.584962500721156,0.0468520303565568,"*",0.01966002,"LOC400927-CSNK1E","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0030426//growth cone;GO:0030529//intracellular ribonucleoprotein complex;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0043025//neuronal cell body","GO:0003723//RNA binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity","GO:0030178//negative regulation of Wnt signaling pathway;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:1990090//cellular response to nerve growth factor stimulus;GO:0097711//ciliary basal body-plasma membrane docking;GO:2000052//positive regulation of non-canonical Wnt signaling pathway;GO:0032091//negative regulation of protein binding;GO:1902004//positive regulation of amyloid-beta formation;GO:0006897//endocytosis;GO:0032922//circadian regulation of gene expression;GO:0007165//signal transduction;GO:0006281//DNA repair;GO:1905426//positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation;GO:0006468//protein phosphorylation;GO:0006364//rRNA processing;GO:0008360//regulation of cell shape;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0042752//regulation of circadian rhythm;GO:0010389//regulation of G2/M transition of mitotic cell cycle;GO:0018105//peptidyl-serine phosphorylation;GO:0034613//cellular protein localization;GO:0016055//Wnt signaling pathway;GO:0000086//G2/M transition of mitotic cell cycle;GO:0048512//circadian behavior;GO:1903827//regulation of cellular protein localization","K08960//casein kinase 1, epsilon [EC:2.7.11.1]","NP_001885.1//casein kinase I isoform epsilon [Homo sapiens]","1//3"]
[8399,924,0.18,0.27,0.584962500721156,0.78091745073435,"*",0.685686,"PLA2G10","GO:0005615//extracellular space;GO:0005576//extracellular region","GO:0004620//phospholipase activity;GO:0102567//phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine);GO:0005509//calcium ion binding;GO:0102568//phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine);GO:0004623//phospholipase A2 activity","GO:0010744//positive regulation of macrophage derived foam cell differentiation;GO:0016042//lipid catabolic process;GO:0019369//arachidonic acid metabolic process;GO:0032270//positive regulation of cellular protein metabolic process;GO:0043433//negative regulation of DNA binding transcription factor activity;GO:0043030//regulation of macrophage activation;GO:0032308//positive regulation of prostaglandin secretion;GO:0010884//positive regulation of lipid storage;GO:0006654//phosphatidic acid biosynthetic process;GO:0036152//phosphatidylethanolamine acyl-chain remodeling;GO:0050482//arachidonic acid secretion;GO:0051977//lysophospholipid transport;GO:0036151//phosphatidylcholine acyl-chain remodeling;GO:0042632//cholesterol homeostasis;GO:0007411//axon guidance;GO:0036150//phosphatidylserine acyl-chain remodeling;GO:0036149//phosphatidylinositol acyl-chain remodeling;GO:0090370//negative regulation of cholesterol efflux;GO:1990830//cellular response to leukemia inhibitory factor;GO:0006644//phospholipid metabolic process;GO:0036148//phosphatidylglycerol acyl-chain remodeling;GO:0090238//positive regulation of arachidonic acid secretion","K01047//secretory phospholipase A2 [EC:3.1.1.4]","NP_003552.1//group 10 secretory phospholipase A2 preproprotein [Homo sapiens]","2//1"]
[100129583,1627,0.06,0.09,0.584962500721156,1.01076013890121,"*",0.998548,"FAM47E","GO:0005737//cytoplasm","NA","NA","K00522//ferritin heavy chain [EC:1.16.3.2];K22267//starch-binding domain-containing protein 1","NP_001229865.1//protein FAM47E isoform b [Homo sapiens];NP_001130042.1//protein FAM47E isoform a [Homo sapiens]","1//3;2//1"]
[50859,1544,0.16,0.24,0.584962500721156,0.831302844401357,"*",0.751524,"SPOCK3","GO:0031012//extracellular matrix;GO:0005615//extracellular space;GO:0005578//proteinaceous extracellular matrix","GO:0008191//metalloendopeptidase inhibitor activity;GO:0005509//calcium ion binding;GO:0005539//glycosaminoglycan binding","GO:0019800//peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan;GO:0007165//signal transduction;GO:0010951//negative regulation of endopeptidase activity;GO:2000146//negative regulation of cell motility","K08136//sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican)","NP_001191287.1//testican-3 isoform 9 precursor [Homo sapiens];XP_011815041.1//PREDICTED: testican-3 isoform X4 [Colobus angolensis palliatus];XP_011815044.1//PREDICTED: testican-3 isoform X7 [Colobus angolensis palliatus];XP_021554515.1//testican-3 isoform X4 [Neomonachus schauinslandi];NP_058646.2//testican-3 isoform 2 precursor [Homo sapiens];XP_016863746.1//PREDICTED: testican-3 isoform X1 [Homo sapiens]","1//3;2//1"]
[43,2170,0.5,0.75,0.584962500721156,0.440210757390896,"*",0.29363,"ACHE","GO:0016020//membrane;GO:0005605//basal lamina;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0031594//neuromuscular junction;GO:0030054//cell junction;GO:0031225//anchored component of membrane;GO:0048471//perinuclear region of cytoplasm;GO:0009986//cell surface;GO:0005794//Golgi apparatus;GO:0005576//extracellular region;GO:0043083//synaptic cleft;GO:0045202//synapse;GO:0005886//plasma membrane","GO:0001540//amyloid-beta binding;GO:0017171//serine hydrolase activity;GO:0043621//protein self-association;GO:0043236//laminin binding;GO:0042803//protein homodimerization activity;GO:0004104//cholinesterase activity;GO:0042166//acetylcholine binding;GO:0005518//collagen binding;GO:0016787//hydrolase activity;GO:0003990//acetylcholinesterase activity","GO:0060041//retina development in camera-type eye;GO:0007399//nervous system development;GO:0031623//receptor internalization;GO:0045212//neurotransmitter receptor biosynthetic process;GO:0006260//DNA replication;GO:0007416//synapse assembly;GO:0008283//cell proliferation;GO:0042982//amyloid precursor protein metabolic process;GO:0001507//acetylcholine catabolic process in synaptic cleft;GO:0009611//response to wounding;GO:0042136//neurotransmitter biosynthetic process;GO:0007517//muscle organ development;GO:0032223//negative regulation of synaptic transmission, cholinergic;GO:0051262//protein tetramerization;GO:0006581//acetylcholine catabolic process;GO:0050714//positive regulation of protein secretion;GO:0007155//cell adhesion;GO:0006656//phosphatidylcholine biosynthetic process;GO:0001919//regulation of receptor recycling;GO:0002076//osteoblast development","K01049//acetylcholinesterase [EC:3.1.1.7]","XP_016867709.1//PREDICTED: acetylcholinesterase isoform X4 [Homo sapiens];XP_018886475.1//PREDICTED: acetylcholinesterase isoform X2 [Gorilla gorilla gorilla];XP_009200999.1//acetylcholinesterase isoform X1 [Papio anubis];XP_016813400.1//PREDICTED: acetylcholinesterase isoform X4 [Pan troglodytes]","4;1//3"]
[56121,2891,0.08,0.12,0.584962500721156,0.609349329390893,"*",0.451538,"PCDHB15","GO:0005887//integral component of plasma membrane","GO:0005509//calcium ion binding","GO:0007416//synapse assembly;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007268//chemical synaptic transmission","K16494//protocadherin beta","XP_003780466.1//PREDICTED: LOW QUALITY PROTEIN: protocadherin beta-15 [Pongo abelii]","3//A2MP1"]
[122060,1968,0.08,0.12,0.584962500721156,1.01613865417224,"*",0.997882,"SLAIN1","GO:0005856//cytoskeleton;GO:0005737//cytoplasm","NA","NA","K16580//SLAIN motif-containing protein 1/2","NP_001035243.2//SLAIN motif-containing protein 1 isoform A precursor [Homo sapiens];XP_015495887.1//PREDICTED: SLAIN motif-containing protein 1 isoform X2 [Parus major];NP_001229797.1//SLAIN motif-containing protein 1 isoform C [Homo sapiens];AAH45177.2//SLAIN1 protein, partial [Homo sapiens];XP_019776699.1//PREDICTED: SLAIN motif-containing protein 1 isoform X2 [Tursiops truncatus]","1//3;3//A2MP1"]
[144195,4368,0.02,0.03,0.584962500721156,1.00858714840341,"*",0.998548,"SLC2A14","GO:0016021//integral component of membrane","GO:0005355//glucose transmembrane transporter activity","NA","K08142//MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 3","XP_005570090.1//PREDICTED: solute carrier family 2, facilitated glucose transporter member 3 [Macaca fascicularis]","1//3;3//A2MP1"]
[163589,2501,0.02,0.03,0.584962500721156,1.00852337835104,"*",0.998548,"TDRD5","GO:0071546//pi-body;GO:0033391//chromatoid body","NA","GO:0043046//DNA methylation involved in gamete generation;GO:0030719//P granule organization;GO:0007286//spermatid development","K18407//tudor domain-containing protein 5","NP_775804.2//tudor domain-containing protein 5 isoform 2 [Homo sapiens];NP_001186014.1//tudor domain-containing protein 5 isoform 1 [Homo sapiens]","1//3;4;2//1"]
[91851,4101,0.04,0.06,0.584962500721156,0.782200111690352,"*",0.685686,"CHRDL1","GO:0005788//endoplasmic reticulum lumen;GO:0005576//extracellular region","NA","GO:0043687//post-translational protein modification;GO:0007399//nervous system development;GO:0030514//negative regulation of BMP signaling pathway;GO:0001654//eye development;GO:0030154//cell differentiation;GO:0048749//compound eye development;GO:0030509//BMP signaling pathway;GO:0001503//ossification;GO:0044267//cellular protein metabolic process","K17280//chordin-like protein 2","XP_012605477.1//chordin-like protein 1 isoform X1 [Microcebus murinus];XP_008064999.1//chordin-like protein 1 isoform X4 [Carlito syrichta];NP_660277.2//chordin-like protein 1 isoform 3 precursor [Homo sapiens];XP_012605485.1//chordin-like protein 1 isoform X2 [Microcebus murinus]","1//3;3//A2MP1;2//1"]
[2563,1942,0.08,0.12,0.584962500721156,0.782144256212511,"*",0.685686,"GABRD","GO:0030054//cell junction;GO:0034707//chloride channel complex;GO:1902711//GABA-A receptor complex;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0045202//synapse;GO:0045211//postsynaptic membrane","GO:0005230//extracellular ligand-gated ion channel activity;GO:0004890//GABA-A receptor activity;GO:0005254//chloride channel activity","GO:0006810//transport;GO:0007165//signal transduction;GO:0007268//chemical synaptic transmission","K05184//gamma-aminobutyric acid receptor subunit delta","NP_000806.2//gamma-aminobutyric acid receptor subunit delta precursor [Homo sapiens]",4]
[728116,4019,0.04,0.06,0.584962500721156,0.782088408711175,"*",0.685686,"ZBTB8B","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K10495//zinc finger and BTB domain-containing protein 8","EAX07524.1//hCG1788238, partial [Homo sapiens]","1//3"]
[2676,1980,0.08,0.12,0.584962500721156,0.781976737631184,"*",0.685686,"GFRA3","GO:0009897//external side of plasma membrane;GO:0019898//extrinsic component of membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0031225//anchored component of membrane","GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005102//receptor binding;GO:0008046//axon guidance receptor activity","GO:0007399//nervous system development;GO:0048485//sympathetic nervous system development;GO:0000165//MAPK cascade;GO:0007165//signal transduction;GO:0001764//neuron migration;GO:0007422//peripheral nervous system development;GO:0007411//axon guidance","K19895//GDNF family receptor alpha 1","NP_001487.2//GDNF family receptor alpha-3 preproprotein [Homo sapiens]","3//A2MP1"]
[345462,2644,0.12,0.18,0.584962500721156,0.666015041110518,"*",0.546646,"ZNF879","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_014922199.1//PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 879 [Acinonyx jubatus]","1//3;2//1"]
[441151,4637,0.02,0.03,0.584962500721156,0.734933649524091,"*",0.623548,"TMEM151B","GO:0016021//integral component of membrane","NA","NA","K22020//mucin-19","NP_001131032.1//transmembrane protein 151B [Homo sapiens]","1//3"]
[389170,1976,0.24,0.36,0.584962500721156,0.60876773971679,"*",0.452136,"LEKR1","NA","NA","NA","K20478//golgin subfamily B member 1","XP_011511118.1//PREDICTED: leucine-, glutamate- and lysine-rich protein 1 isoform X11 [Homo sapiens];XP_006713694.1//PREDICTED: leucine-, glutamate- and lysine-rich protein 1 isoform X1 [Homo sapiens]","1//3;2//1"]
[3357,1857,0.26,0.39,0.584962500721156,0.608716431858407,"*",0.452136,"HTR2B","GO:0005887//integral component of plasma membrane;GO:0030054//cell junction;GO:0045202//synapse;GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0043005//neuron projection","GO:0051378//serotonin binding;GO:0004993//G-protein coupled serotonin receptor activity;GO:0001965//G-protein alpha-subunit binding;GO:0008144//drug binding;GO:0030594//neurotransmitter receptor activity;GO:0005096//GTPase activator activity","GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0016310//phosphorylation;GO:0050795//regulation of behavior;GO:0001819//positive regulation of cytokine production;GO:0070371//ERK1 and ERK2 cascade;GO:0071502//cellular response to temperature stimulus;GO:0007610//behavior;GO:0042493//response to drug;GO:0001755//neural crest cell migration;GO:0070528//protein kinase C signaling;GO:0019722//calcium-mediated signaling;GO:0043066//negative regulation of apoptotic process;GO:0003300//cardiac muscle hypertrophy;GO:0006182//cGMP biosynthetic process;GO:0007202//activation of phospholipase C activity;GO:0051209//release of sequestered calcium ion into cytosol;GO:0048598//embryonic morphogenesis;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0051000//positive regulation of nitric-oxide synthase activity;GO:0042310//vasoconstriction;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0051781//positive regulation of cell division;GO:0007210//serotonin receptor signaling pathway;GO:0003007//heart morphogenesis;GO:0001938//positive regulation of endothelial cell proliferation;GO:0006874//cellular calcium ion homeostasis;GO:0007186//G-protein coupled receptor signaling pathway;GO:0043406//positive regulation of MAP kinase activity;GO:0010513//positive regulation of phosphatidylinositol biosynthetic process;GO:0014033//neural crest cell differentiation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0010507//negative regulation of autophagy;GO:0060548//negative regulation of cell death;GO:0014827//intestine smooth muscle contraction;GO:0002031//G-protein coupled receptor internalization;GO:0050715//positive regulation of cytokine secretion;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0008284//positive regulation of cell proliferation","K04157//5-hydroxytryptamine receptor 2","NP_000858.3//5-hydroxytryptamine receptor 2B isoform 1 [Homo sapiens]","1//3;4"]
[3851,2147,0.3,0.45,0.584962500721156,0.534861479384615,"*",0.380872,"KRT4","NA","NA","NA","K07605//type II keratin, basic","XP_017357230.1//PREDICTED: keratin, type II cytoskeletal 4 [Cebus capucinus imitator]","3//A2MP1"]
[57159,1947,0.08,0.12,0.584962500721156,0.781307380269634,"*",0.685686,"TRIM54","GO:0030018//Z disc;GO:0005875//microtubule associated complex;GO:0005874//microtubule","GO:0008270//zinc ion binding;GO:0004871//signal transducer activity;GO:0008017//microtubule binding","GO:0055001//muscle cell development;GO:0070507//regulation of microtubule cytoskeleton organization;GO:0007165//signal transduction;GO:0007275//multicellular organism development;GO:0007026//negative regulation of microtubule depolymerization;GO:0007017//microtubule-based process","K10653//tripartite motif-containing protein 54","NP_912730.2//tripartite motif-containing protein 54 isoform 2 [Homo sapiens];NP_115935.3//tripartite motif-containing protein 54 isoform 1 [Homo sapiens]","3//A2MP1;2//1"]
[93035,19969,0.06,0.09,0.584962500721156,0.384167835298821,"*",0.24064,"PKHD1L1","NA","NA","NA","K19865//fibrocystin","XP_016869458.1//PREDICTED: fibrocystin-L isoform X1 [Homo sapiens]",5]
[345051,3626,0.02,0.03,0.584962500721156,1.00439555141364,"*",0.998548,"REELD1","NA","NA","NA","K02599//Notch 1","NP_001341560.1//reeler domain containing 1 precursor [Homo sapiens]","1//3"]
[79400,2725,0.06,0.09,0.584962500721156,0.780973131122995,"*",0.685686,"NOX5","GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0050661//NADP binding;GO:0020037//heme binding;GO:0005509//calcium ion binding;GO:0050660//flavin adenine dinucleotide binding;GO:0016175//superoxide-generating NADPH oxidase activity;GO:0015252//proton channel activity","GO:0050663//cytokine secretion;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0001525//angiogenesis;GO:0000910//cytokinesis;GO:0055114//oxidation-reduction process;GO:0006915//apoptotic process;GO:0008283//cell proliferation;GO:0034599//cellular response to oxidative stress;GO:0042554//superoxide anion generation;GO:0043012//regulation of fusion of sperm to egg plasma membrane;GO:0010155//regulation of proton transport;GO:0001935//endothelial cell proliferation","K21424//NADPH oxidase 5 [EC:1.6.3.-]","NP_078781.3//NADPH oxidase 5 isoform 1 [Homo sapiens];NP_001171708.1//NADPH oxidase 5 isoform 2 [Homo sapiens];NP_001171709.1//NADPH oxidase 5 isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[64577,2405,0.32,0.48,0.584962500721156,0.453467849688401,"*",0.305198,"ALDH8A1","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0005622//intracellular","GO:0001758//retinal dehydrogenase activity","GO:0042573//retinoic acid metabolic process;GO:0042904//9-cis-retinoic acid biosynthetic process;GO:0042574//retinal metabolic process","K00129//aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5];K07249//retinal dehydrogenase [EC:1.2.1.36];K06564//insulin-like growth factor 2 receptor;K00149//aldehyde dehydrogenase family 9 member A1 [EC:1.2.1.47 1.2.1.3]","NP_072090.1//aldehyde dehydrogenase family 8 member A1 isoform 1 [Homo sapiens];NP_739577.1//aldehyde dehydrogenase family 8 member A1 isoform 2 [Homo sapiens];NP_001180409.1//aldehyde dehydrogenase family 8 member A1 isoform 3 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[145501,2660,0.12,0.18,0.584962500721156,0.665761146996035,"*",0.546646,"ISM2","GO:0005576//extracellular region","NA","NA","K10955//mucin-2","CAD62605.1//unnamed protein product, partial [Homo sapiens];NP_954993.1//isthmin-2 isoform 1 precursor [Homo sapiens]","3//A2MP1;2//1"]
[55259,2012,0.08,0.12,0.584962500721156,0.780583535062714,"*",0.685686,"CASC1","NA","NA","NA","K17580//cancer susceptibility candidate protein 1","NP_001338996.1//protein CASC1 isoform l [Homo sapiens];NP_001338991.1//protein CASC1 isoform g [Homo sapiens];NP_060742.3//protein CASC1 isoform a [Homo sapiens];NP_001076442.1//protein CASC1 isoform b [Homo sapiens];XP_016875054.1//PREDICTED: protein CASC1 isoform X9 [Homo sapiens];NP_001338992.1//protein CASC1 isoform h [Homo sapiens];NP_001191030.1//protein CASC1 isoform e [Homo sapiens];NP_001191031.1//protein CASC1 isoform d [Homo sapiens];NP_001076441.1//protein CASC1 isoform c [Homo sapiens];NP_001338993.1//protein CASC1 isoform i [Homo sapiens]","4;1//3;2//1"]
[23440,2702,0.06,0.09,0.584962500721156,0.780527910211644,"*",0.685686,"OTP","NA","NA","NA","K09452//homeobox protein aristaless-related","XP_004058722.2//PREDICTED: homeobox protein orthopedia [Gorilla gorilla gorilla]","2//1"]
[55885,3838,0.04,0.06,0.584962500721156,0.78047229328773,"*",0.685686,"LMO3","GO:0005737//cytoplasm","GO:0046872//metal ion binding","GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0006355//regulation of transcription, DNA-templated;GO:0045600//positive regulation of fat cell differentiation;GO:0006351//transcription, DNA-templated;GO:0035360//positive regulation of peroxisome proliferator activated receptor signaling pathway;GO:2000324//positive regulation of glucocorticoid receptor signaling pathway","K15612//rhombotin-2","XP_007942636.1//PREDICTED: LIM domain only protein 3 isoform X1 [Orycteropus afer afer];NP_001230541.1//LIM domain only protein 3 isoform 3 [Homo sapiens];XP_005664099.1//LIM domain only protein 3 isoform X1 [Sus scrofa];XP_020946522.1//LIM domain only protein 3 isoform X2 [Sus scrofa];XP_008967811.1//PREDICTED: LIM domain only protein 3 isoform X1 [Pan paniscus];XP_005570312.1//PREDICTED: LIM domain only protein 3 isoform X1 [Macaca fascicularis]","4;1//3;2//1"]
[83733,2089,0.08,0.12,0.584962500721156,0.780194327516205,"*",0.685686,"SLC25A18","NA","NA","NA","K15107//solute carrier family 25 (mitochondrial glutamate transporter), member 18/22","XP_011544451.1//PREDICTED: mitochondrial glutamate carrier 2 isoform X1 [Homo sapiens]","1//3;2//1"]
[55057,5245,0.06,0.09,0.584962500721156,0.665558171036585,"*",0.546646,"CRYBG2","NA","GO:0030246//carbohydrate binding","NA","K16810//TBCC domain-containing protein 1;K01886//glutaminyl-tRNA synthetase [EC:6.1.1.18]","XP_011539975.1//PREDICTED: absent in melanoma 1-like protein isoform X3 [Homo sapiens]","3//A2MP1"]
[169436,2794,0.06,0.09,0.584962500721156,0.780083196638416,"*",0.685686,"STKLD1","NA","GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding","NA","K17546//probable inactive protein kinase-like protein SgK071","NP_714921.4//serine/threonine kinase-like domain-containing protein STKLD1 [Homo sapiens]",4]
[8352,459,0.38,0.57,0.584962500721156,0.782703170215807,"*",0.685686,"HIST1H3C","NA","NA","NA","K11253//histone H3","XP_012669845.1//PREDICTED: uncharacterized protein LOC105888650 [Clupea harengus]","2//1"]
[2861,5614,0.1,0.15,0.584962500721156,0.512128993086109,"*",0.357054,"GPR37","GO:0005783//endoplasmic reticulum;GO:0005887//integral component of plasma membrane;GO:0000151//ubiquitin ligase complex;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0043235//receptor complex","GO:0008528//G-protein coupled peptide receptor activity;GO:0036505//prosaposin receptor activity;GO:0031072//heat shock protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0042277//peptide binding;GO:0030544//Hsp70 protein binding;GO:0004930//G-protein coupled receptor activity","GO:0045964//positive regulation of dopamine metabolic process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:1903206//negative regulation of hydrogen peroxide-induced cell death;GO:0043410//positive regulation of MAPK cascade;GO:0031987//locomotion involved in locomotory behavior;GO:0042416//dopamine biosynthetic process","K04243//G protein-coupled receptor 37 (endothelin receptor type B-like)","NP_005293.1//prosaposin receptor GPR37 precursor [Homo sapiens]",4]
[619373,1663,0.1,0.15,0.584962500721156,0.781809290792291,"*",0.685686,"MBOAT4","GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005789//endoplasmic reticulum membrane","GO:0016412//serine O-acyltransferase activity;GO:0008374//O-acyltransferase activity","GO:0018191//peptidyl-serine octanoylation","K13517//lysophospholipid acyltransferase 1/2 [EC:2.3.1.51 2.3.1.-]","NP_001094386.1//ghrelin O-acyltransferase [Homo sapiens]","1//3"]
[10677,3163,0.1,0.15,0.584962500721156,0.665862681409181,"*",0.546646,"AVIL","NA","GO:0051015//actin filament binding","GO:0060271//cilium assembly;GO:0007010//cytoskeleton organization;GO:0010976//positive regulation of neuron projection development","K08017//advillin","XP_012632595.1//advillin isoform X7 [Microcebus murinus]","3//A2MP1"]
[162417,2086,0.46,0.69,0.584962500721156,0.423768030086642,"*",0.27863,"NAGS","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0034618//arginine binding;GO:0004042//acetyl-CoA:L-glutamate N-acetyltransferase activity;GO:0103045//methione N-acyltransferase activity","GO:0006536//glutamate metabolic process;GO:0006526//arginine biosynthetic process;GO:0000050//urea cycle","K11067//N-acetylglutamate synthase [EC:2.3.1.1]","NP_694551.1//N-acetylglutamate synthase, mitochondrial [Homo sapiens]","2//1"]
[5207,1591,0.1,0.15,0.584962500721156,0.780806113772455,"*",0.685686,"PFKFB1","GO:0043540//6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex","GO:0004331//fructose-2,6-bisphosphate 2-phosphatase activity;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0003873//6-phosphofructo-2-kinase activity","GO:0006003//fructose 2,6-bisphosphate metabolic process;GO:0006000//fructose metabolic process","K19028//6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 1 [EC:2.7.1.105 3.1.3.46]","XP_016799129.1//PREDICTED: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X2 [Pan troglodytes];XP_008051654.1//6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X3 [Carlito syrichta];EAW93207.1//6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 [Homo sapiens]","1//3;3//A2MP1"]
[8970,481,0.38,0.57,0.584962500721156,0.780750457195809,"*",0.685686,"HIST1H2BJ","NA","NA","NA","K11252//histone H2B","XP_004019080.2//PREDICTED: histone H2B type 1 isoform X1 [Ovis aries]","3//A2MP1"]
[1912,2607,36,53.93,0.583091127293523,{"v":1.94544317472119e-25,"d":"1.95E-25"},"*",{"v":6.5522e-27,"d":"6.55E-27"},"PHC2","GO:0035102//PRC1 complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031519//PcG protein complex;GO:0000792//heterochromatin","GO:0003677//DNA binding;GO:0042802//identical protein binding;GO:0008270//zinc ion binding","GO:0007275//multicellular organism development;GO:0007283//spermatogenesis","K11457//polyhomeotic-like protein 2","NP_932157.1//polyhomeotic-like protein 2 isoform a [Homo sapiens];NP_001317417.1//polyhomeotic-like protein 2 isoform c [Homo sapiens];AAH68573.1//PHC2 protein, partial [Homo sapiens]","1//3;3//A2MP1;2//1"]
[10398,1115,1.87,2.8,0.58238855705733,0.128365080260636,"*",0.0628968,"MYL9","GO:0005859//muscle myosin complex;GO:0005829//cytosol","GO:0005509//calcium ion binding;GO:0008307//structural constituent of muscle","GO:0006937//regulation of muscle contraction;GO:0006936//muscle contraction;GO:0045652//regulation of megakaryocyte differentiation;GO:0070527//platelet aggregation","K12755//myosin regulatory light chain 9","NP_852667.1//myosin regulatory light polypeptide 9 isoform b [Homo sapiens];XP_017719010.1//PREDICTED: myosin regulatory light polypeptide 9 isoform X1 [Rhinopithecus bieti]","4;2//1"]
[10517,3293,1.39,2.08,0.581498645417585,0.0304467875268817,"*",0.01205368,"FBXW10","GO:0005829//cytosol","GO:0004842//ubiquitin-protein transferase activity","GO:0043687//post-translational protein modification;GO:0000209//protein polyubiquitination","K10266//F-box and WD-40 domain protein 10","NP_001254514.1//F-box/WD repeat-containing protein 10 isoform 1 [Homo sapiens];NP_001254515.1//F-box/WD repeat-containing protein 10 isoform 2 [Homo sapiens]","1//3"]
[404217,1290,19.69,29.4,0.578353043822173,{"v":1.78873884153005e-07,"d":"1.79E-07"},"*",{"v":2.66396e-08,"d":"2.66E-08"},"CTXN1","GO:0016021//integral component of membrane","NA","NA","K16628//collagen, type VII, alpha;K03129//transcription initiation factor TFIID subunit 4","EAW68956.1//cortexin 1, partial [Homo sapiens]","3//A2MP1"]
[4494,457,7.2,10.74,0.576925181655738,0.152146402756923,"*",0.0773876,"MT1F","NA","NA","NA","K14739//metallothionein 1/2","AAF23355.1//hqp0376 protein [Homo sapiens]","1//3;3//A2MP1"]
[84330,1377,12.13,18.06,0.574218342360348,{"v":7.36685431456311e-05,"d":"7.37E-05"},"*",{"v":1.662546e-05,"d":"1.66E-05"},"ZNF414","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K16628//collagen, type VII, alpha;K08559//nuclear receptor subfamily 4 group A member 3;K19994//PML-RARA-regulated adapter molecule 1","NP_115746.2//zinc finger protein 414 isoform 2 [Homo sapiens];NP_001139647.1//zinc finger protein 414 isoform 1 [Homo sapiens]","1//3;2//1"]
[10265,2075,2.17,3.23,0.573839122249446,0.0506698957060646,"*",0.0214968,"IRX5","GO:0005634//nucleus","GO:0005499//vitamin D binding;GO:0043565//sequence-specific DNA binding","GO:0006355//regulation of transcription, DNA-templated;GO:0060040//retinal bipolar neuron differentiation;GO:0007601//visual perception;GO:0006351//transcription, DNA-templated;GO:0002027//regulation of heart rate;GO:0008406//gonad development;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0050896//response to stimulus;GO:0042551//neuron maturation","K13046//tolkin [EC:3.4.24.-];K13172//serine/arginine repetitive matrix protein 2","NP_005844.4//iroquois-class homeodomain protein IRX-5 isoform 1 [Homo sapiens];NP_001239126.1//iroquois-class homeodomain protein IRX-5 isoform 2 [Homo sapiens]","1//3;5"]
[4255,1372,2.07,3.08,0.573299583195576,0.136613780697118,"*",0.0679648,"MGMT","GO:0016020//membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0003908//methylated-DNA-[protein]-cysteine S-methyltransferase activity;GO:0005509//calcium ion binding","GO:0042493//response to drug;GO:0043066//negative regulation of apoptotic process;GO:0009636//response to toxic substance;GO:0045471//response to ethanol;GO:0006307//DNA dealkylation involved in DNA repair;GO:0071407//cellular response to organic cyclic compound;GO:0071479//cellular response to ionizing radiation;GO:0034599//cellular response to oxidative stress;GO:0060644//mammary gland epithelial cell differentiation;GO:0043281//regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:2000781//positive regulation of double-strand break repair;GO:0045739//positive regulation of DNA repair;GO:0051593//response to folic acid;GO:0060548//negative regulation of cell death","K00567//methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]","NP_002403.2//methylated-DNA--protein-cysteine methyltransferase [Homo sapiens]",4]
[100132247,3827,7.9,11.75,0.572736198387897,{"v":8.79869525808056e-09,"d":"8.80E-09"},"*",{"v":1.107686e-09,"d":"1.11E-09"},"NPIPB5","GO:0005654//nucleoplasm;GO:0016021//integral component of membrane","NA","NA","K17582//antigen KI-67","NP_001129337.1//nuclear pore complex interacting protein family member [Homo sapiens]","1//3"]
[115708,3257,15.84,23.55,0.572154724420536,{"v":3.03533051651143e-14,"d":"3.04E-14"},"*",{"v":2.2441e-15,"d":"2.24E-15"},"TRMT61A","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031515//tRNA (m1A) methyltransferase complex","GO:0016429//tRNA (adenine-N1-)-methyltransferase activity","GO:0006400//tRNA modification","K07442//tRNA (adenine57-N1/adenine58-N1)-methyltransferase catalytic subunit [EC:2.1.1.219 2.1.1.220]","XP_007986137.1//PREDICTED: tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A [Chlorocebus sabaeus]","2//1"]
[113179,1751,7.15,10.63,0.572126449865353,0.00278892393705293,"*",0.000854276,"ADAT3","GO:0005654//nucleoplasm","GO:0046872//metal ion binding;GO:0003824//catalytic activity","GO:0006400//tRNA modification;GO:0009451//RNA modification","K15442//tRNA-specific adenosine deaminase 3","NP_612431.2//probable inactive tRNA-specific adenosine deaminase-like protein 3 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[51042,653,39.42,58.6,0.571972888266124,{"v":3.78263290249799e-07,"d":"3.78E-07"},"*",{"v":5.87736e-08,"d":"5.88E-08"},"ZNF593","GO:0005634//nucleus;GO:0005730//nucleolus;GO:0030687//preribosome, large subunit precursor","GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0043023//ribosomal large subunit binding;GO:0003676//nucleic acid binding","GO:0000055//ribosomal large subunit export from nucleus;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:1903026//negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding;GO:0006351//transcription, DNA-templated","K14821//bud site selection protein 20","NP_056955.2//zinc finger protein 593 [Homo sapiens]",4]
[83480,1687,3.38,5.02,0.570664117668587,0.040103965106383,"*",0.0165196,"PUS3","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0009982//pseudouridine synthase activity","GO:0031119//tRNA pseudouridine synthesis;GO:0006400//tRNA modification;GO:1990481//mRNA pseudouridine synthesis","K01855//tRNA pseudouridine38/39 synthase [EC:5.4.99.45]","NP_112597.3//tRNA pseudouridine(38/39) synthase isoform 1 [Homo sapiens];XP_005271744.1//PREDICTED: tRNA pseudouridine(38/39) synthase isoform X1 [Homo sapiens]","1//3;3//A2MP1"]
[158056,3669,2.81,4.17,0.569477253223738,1.45180909256449E-3,"*",0.000419256,"MAMDC4","GO:0016021//integral component of membrane","NA","GO:0015031//protein transport","K18762//zygote arrest protein 1","NP_996803.2//apical endosomal glycoprotein precursor [Homo sapiens]","2//1"]
[10435,2043,13.98,20.73,0.568355755733978,{"v":4.07398858314351e-08,"d":"4.07E-08"},"*",{"v":5.5981e-09,"d":"5.60E-09"},"CDC42EP2","GO:0016020//membrane;GO:0012505//endomembrane system;GO:0015630//microtubule cytoskeleton;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0001515//opioid peptide activity;GO:0017049//GTP-Rho binding;GO:0005096//GTPase activator activity","GO:0007266//Rho protein signal transduction;GO:0007015//actin filament organization;GO:0031334//positive regulation of protein complex assembly;GO:0030036//actin cytoskeleton organization;GO:0031274//positive regulation of pseudopodium assembly;GO:0030838//positive regulation of actin filament polymerization;GO:0008360//regulation of cell shape","NA","EAW74374.1//CDC42 effector protein (Rho GTPase binding) 2, partial [Homo sapiens]","3//A2MP1"]
[387496,1246,5.62,8.33,0.567746365144622,0.0113662884507042,"*",0.00399108,"RASL11A","GO:0016020//membrane;GO:0005730//nucleolus","GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0007165//signal transduction;GO:0006351//transcription, DNA-templated;GO:0045943//positive regulation of transcription from RNA polymerase I promoter","K07852//Ras-like protein family member 11A","NP_996563.1//ras-like protein family member 11A isoform 1 [Homo sapiens];XP_011753914.1//PREDICTED: ras-like protein family member 11A [Macaca nemestrina]","1//3"]
[55009,912,48.73,72.22,0.567588197756324,{"v":9.6622966763285e-12,"d":"9.66E-12"},"*",{"v":8.76466e-13,"d":"8.76E-13"},"C19orf24","GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005737//cytoplasm","NA","NA","K03129//transcription initiation factor TFIID subunit 4;K02891//large subunit ribosomal protein L22e","EAW69518.1//chromosome 19 open reading frame 24, isoform CRA_a [Homo sapiens]","3//A2MP1"]
[401399,2411,0.27,0.4,0.567040592723894,0.199876384425941,"*",0.106695,"PRRT4","GO:0016021//integral component of membrane","NA","NA","K16628//collagen, type VII, alpha","NP_001108198.2//proline-rich transmembrane protein 4 isoform 2 precursor [Homo sapiens];NP_001167635.1//proline-rich transmembrane protein 4 isoform 1 precursor [Homo sapiens]","1//3;2//1"]
[644890,638,0.27,0.4,0.567040592723894,0.781251652211127,"*",0.685686,"MEIG1","GO:0005634//nucleus","NA","GO:0030154//cell differentiation;GO:0007283//spermatogenesis","NA","EAW86246.1//hCG2039913, partial [Homo sapiens]","2//1"]
[140456,2748,0.75,1.11,0.565597175854225,0.191790122057089,"*",0.1017902,"ASB11","GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005622//intracellular","NA","GO:0043687//post-translational protein modification;GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction","K10333//ankyrin repeat and SOCS box protein 11","NP_543149.1//ankyrin repeat and SOCS box protein 11 isoform a [Homo sapiens];NP_001012428.1//ankyrin repeat and SOCS box protein 11 isoform b [Homo sapiens];NP_001188512.1//ankyrin repeat and SOCS box protein 11 isoform c [Homo sapiens]","1//3;2//1"]
[23305,6316,0.25,0.37,0.565597175854225,0.275350957602085,"*",0.1587224,"ACSL6","GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005741//mitochondrial outer membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005778//peroxisomal membrane","GO:0005524//ATP binding;GO:0004467//long-chain fatty acid-CoA ligase activity;GO:0003824//catalytic activity;GO:0102391//decanoate--CoA ligase activity;GO:0042803//protein homodimerization activity;GO:0019899//enzyme binding;GO:0016874//ligase activity","GO:0008152//metabolic process;GO:0035338//long-chain fatty-acyl-CoA biosynthetic process;GO:0001676//long-chain fatty acid metabolic process;GO:0006637//acyl-CoA metabolic process","K01897//long-chain acyl-CoA synthetase [EC:6.2.1.3]","XP_006872995.1//PREDICTED: long-chain-fatty-acid--CoA ligase 6 isoform X3 [Chrysochloris asiatica];XP_016808253.1//PREDICTED: long-chain-fatty-acid--CoA ligase 6 isoform X2 [Pan troglodytes];XP_016808252.1//PREDICTED: long-chain-fatty-acid--CoA ligase 6 isoform X1 [Pan troglodytes];NP_001192180.1//long-chain-fatty-acid--CoA ligase 6 isoform f [Homo sapiens]","1//3;3//A2MP1;2//1"]
[27113,1853,5.71,8.44,0.563752253344342,0.00150763771737252,"*",0.000436794,"BBC3","GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005741//mitochondrial outer membrane;GO:0005739//mitochondrion","GO:0051117//ATPase binding","GO:0071456//cellular response to hypoxia;GO:0001844//protein insertion into mitochondrial membrane involved in apoptotic signaling pathway;GO:0045926//negative regulation of growth;GO:0097190//apoptotic signaling pathway;GO:0034976//response to endoplasmic reticulum stress;GO:2001056//positive regulation of cysteine-type endopeptidase activity;GO:0097193//intrinsic apoptotic signaling pathway;GO:0006974//cellular response to DNA damage stimulus;GO:0001836//release of cytochrome c from mitochondria;GO:1900740//positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway;GO:1902237//positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway;GO:0043525//positive regulation of neuron apoptotic process;GO:0032464//positive regulation of protein homooligomerization;GO:0032471//negative regulation of endoplasmic reticulum calcium ion concentration;GO:0006915//apoptotic process;GO:0008340//determination of adult lifespan;GO:0070245//positive regulation of thymocyte apoptotic process;GO:0097194//execution phase of apoptosis;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0051209//release of sequestered calcium ion into cytosol;GO:0042981//regulation of apoptotic process;GO:1903896//positive regulation of IRE1-mediated unfolded protein response","K11653//AT-rich interactive domain-containing protein 1;K19475//WAS/WASL-interacting protein;K10132//Bcl-2-binding component 3;K20638//Rho GTPase-activating protein 17","XP_017355891.1//PREDICTED: bcl-2-binding component 3 isoform X2 [Cebus capucinus imitator];NP_001120712.1//bcl-2-binding component 3 isoform 1 [Homo sapiens];NP_001120714.1//bcl-2-binding component 3 isoform 3 [Homo sapiens]","4;2//1"]
[503542,3188,2.45,3.62,0.563207948080635,0.0072602563026784,"*",0.0024266,"SPRN","GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005576//extracellular region;GO:0031982//vesicle;GO:0005886//plasma membrane;GO:0031225//anchored component of membrane","GO:0003676//nucleic acid binding","GO:0006501//C-terminal protein lipidation;GO:0006606//protein import into nucleus","K03129//transcription initiation factor TFIID subunit 4","EAW61350.1//hCG2040575, partial [Homo sapiens]","3//A2MP1"]
[124739,4174,1.74,2.57,0.56268105334515,0.0116669573394985,"*",0.00410688,"USP43","GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0004843//thiol-dependent ubiquitin-specific protease activity;GO:0036459//thiol-dependent ubiquitinyl hydrolase activity;GO:0019785//ISG15-specific protease activity","GO:0019985//translesion synthesis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination","K11856//ubiquitin carboxyl-terminal hydrolase 43 [EC:3.4.19.12]","NP_694942.3//ubiquitin carboxyl-terminal hydrolase 43 isoform 1 [Homo sapiens];NP_001254505.1//ubiquitin carboxyl-terminal hydrolase 43 isoform 2 [Homo sapiens]","4;1//3"]
[6452,9109,2.58,3.81,0.562419932070068,{"v":7.44409305157814e-07,"d":"7.44E-07"},"*",{"v":1.210702E-7,"d":"1.21E-07"},"SH3BP2","NA","GO:0005070//SH3/SH2 adaptor activity;GO:0001784//phosphotyrosine residue binding;GO:0017124//SH3 domain binding","GO:0007165//signal transduction","K07984//SH3-domain binding protein 2","XP_018880723.1//PREDICTED: SH3 domain-binding protein 2 isoform X2 [Gorilla gorilla gorilla];NP_001139327.1//SH3 domain-binding protein 2 isoform c [Homo sapiens];NP_001139328.1//SH3 domain-binding protein 2 isoform b [Homo sapiens]","1//3;4"]
[6405,3538,2.12,3.13,0.562098392369419,0.00981992227949183,"*",0.00338724,"SEMA3F","GO:0005615//extracellular space","GO:0045499//chemorepellent activity;GO:0038191//neuropilin binding","GO:0036486//ventral trunk neural crest cell migration;GO:1902287//semaphorin-plexin signaling pathway involved in axon guidance;GO:0021612//facial nerve structural organization;GO:0048846//axon extension involved in axon guidance;GO:0021785//branchiomotor neuron axon guidance;GO:0097491//sympathetic neuron projection guidance;GO:0048843//negative regulation of axon extension involved in axon guidance;GO:0021637//trigeminal nerve structural organization;GO:0097490//sympathetic neuron projection extension;GO:1902285//semaphorin-plexin signaling pathway involved in neuron projection guidance;GO:1901166//neural crest cell migration involved in autonomic nervous system development;GO:0021675//nerve development;GO:0007411//axon guidance;GO:0061549//sympathetic ganglion development","K06840//semaphorin 3","NP_004177.3//semaphorin-3F isoform 1 precursor [Homo sapiens];BAD92496.1//semaphorin 3F variant, partial [Homo sapiens];NP_001305729.1//semaphorin-3F isoform 2 precursor [Homo sapiens]","4;1//3"]
[2670,3097,0.21,0.31,0.561878887608115,0.402888300357108,"*",0.26132,"GFAP","GO:0097450//astrocyte end-foot;GO:0044297//cell body;GO:0045111//intermediate filament cytoskeleton;GO:0005829//cytosol;GO:0043209//myelin sheath;GO:0005882//intermediate filament;GO:0005737//cytoplasm;GO:0098574//cytoplasmic side of lysosomal membrane","GO:0005178//integrin binding;GO:0042802//identical protein binding;GO:0019900//kinase binding;GO:0005200//structural constituent of cytoskeleton","GO:0009611//response to wounding;GO:0045109//intermediate filament organization;GO:0043254//regulation of protein complex assembly;GO:0014002//astrocyte development;GO:0051580//regulation of neurotransmitter uptake;GO:0010977//negative regulation of neuron projection development;GO:0030198//extracellular matrix organization;GO:0060291//long-term synaptic potentiation;GO:0031102//neuron projection regeneration;GO:0010625//positive regulation of Schwann cell proliferation;GO:1904714//regulation of chaperone-mediated autophagy;GO:0060020//Bergmann glial cell differentiation","K05640//glial fibrillary acidic protein","XP_012353064.1//PREDICTED: glial fibrillary acidic protein isoform X2 [Nomascus leucogenys];XP_003270779.2//PREDICTED: glial fibrillary acidic protein isoform X3 [Nomascus leucogenys];XP_017806300.2//glial fibrillary acidic protein isoform X2 [Papio anubis]","1//3;4;2//1"]
[11077,1916,1.05,1.55,0.561878887608115,0.229778547915028,"*",0.1279792,"HSF2BP","NA","NA","NA","NA","XP_007967686.1//PREDICTED: heat shock factor 2-binding protein isoform X2 [Chlorocebus sabaeus]","1//3"]
[4688,2285,0.4,0.59,0.560714954474479,0.495774793725632,"*",0.3423,"NCF2","GO:0032010//phagolysosome;GO:0005730//nucleolus;GO:0043020//NADPH oxidase complex;GO:0005829//cytosol;GO:0001669//acrosomal vesicle","GO:0009055//electron transfer activity;GO:0016176//superoxide-generating NADPH oxidase activator activity;GO:0008022//protein C-terminus binding;GO:0048365//Rac GTPase binding;GO:0016175//superoxide-generating NADPH oxidase activity","GO:0006801//superoxide metabolic process;GO:0034599//cellular response to oxidative stress;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0042554//superoxide anion generation;GO:0045087//innate immune response;GO:0006968//cellular defense response;GO:0045730//respiratory burst;GO:0006909//phagocytosis;GO:0045454//cell redox homeostasis","K08010//neutrophil cytosolic factor 2","XP_011850731.1//PREDICTED: neutrophil cytosol factor 2 isoform X1 [Mandrillus leucophaeus];NP_001177718.1//neutrophil cytosol factor 2 isoform 3 [Homo sapiens];NP_001177723.1//neutrophil cytosol factor 2 isoform 2 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[116372,3519,8.94,13.18,0.560003633824734,{"v":8.80208725771144e-09,"d":"8.80E-09"},"*",{"v":1.107562e-09,"d":"1.11E-09"},"LYPD1","GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane","GO:0046872//metal ion binding;GO:0004930//G-protein coupled receptor activity","GO:0007186//G-protein coupled receptor signaling pathway","K08412//G protein-coupled receptor 39","XP_017391561.1//PREDICTED: ly6/PLAUR domain-containing protein 1 isoform X1 [Cebus capucinus imitator];XP_011825690.1//PREDICTED: ly6/PLAUR domain-containing protein 1 isoform X1 [Mandrillus leucophaeus];XP_007962958.1//PREDICTED: G-protein coupled receptor 39-like [Chlorocebus sabaeus]","6;1//3;3//A2MP1"]
[4828,1044,19.1,28.14,0.559049690313422,{"v":1.17671902139891E-5,"d":"1.18E-05"},"*",{"v":2.30644e-06,"d":"2.31E-06"},"NMB","GO:0005576//extracellular region;GO:0043005//neuron projection","GO:0031710//neuromedin B receptor binding;GO:0005179//hormone activity","GO:0046887//positive regulation of hormone secretion;GO:0050482//arachidonic acid secretion;GO:0007165//signal transduction;GO:0046888//negative regulation of hormone secretion;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007267//cell-cell signaling;GO:0007218//neuropeptide signaling pathway;GO:0008284//positive regulation of cell proliferation;GO:0042593//glucose homeostasis","K05223//neuromedin B","NP_995580.1//neuromedin-B isoform 2 preproprotein [Homo sapiens];NP_066563.2//neuromedin-B isoform 1 preproprotein [Homo sapiens]","1//3;3//A2MP1"]
[100170229,2415,4.63,6.82,0.558759545763936,0.00124702407464325,"*",0.00035559,"SRRM5","NA","NA","NA","K17498//transcription factor SPN1","BAG60212.1//unnamed protein product [Homo sapiens]","1//3"]
[55512,5269,0.36,0.53,0.557995453120887,0.266378345531915,"*",0.1528332,"SMPD3","GO:0016021//integral component of membrane;GO:0000137//Golgi cis cisterna;GO:0005886//plasma membrane;GO:0000139//Golgi membrane","GO:0046872//metal ion binding;GO:0004767//sphingomyelin phosphodiesterase activity","GO:0006685//sphingomyelin catabolic process;GO:1903543//positive regulation of exosomal secretion;GO:0030072//peptide hormone secretion;GO:0002244//hematopoietic progenitor cell differentiation;GO:0006687//glycosphingolipid metabolic process;GO:2000304//positive regulation of ceramide biosynthetic process;GO:0007049//cell cycle;GO:0006684//sphingomyelin metabolic process","K12352//sphingomyelin phosphodiesterase 3 [EC:3.1.4.12]","NP_061137.1//sphingomyelin phosphodiesterase 3 [Homo sapiens]","3//A2MP1"]
[344838,2119,2.16,3.18,0.557995453120887,0.0526002674493689,"*",0.0224376,"PAQR9","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0003707//steroid hormone receptor activity;GO:0005496//steroid binding","GO:0048545//response to steroid hormone","K10955//mucin-2","XP_016797594.1//PREDICTED: progestin and adipoQ receptor family member 9 isoform X1 [Pan troglodytes]","2//1"]
[80328,1424,1.25,1.84,0.557777671394926,0.235673703222919,"*",0.131838,"ULBP2","GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0009986//cell surface;GO:0005576//extracellular region;GO:0046658//anchored component of plasma membrane;GO:0031225//anchored component of membrane;GO:0005886//plasma membrane","GO:0046703//natural killer cell lectin-like receptor binding","GO:0030101//natural killer cell activation;GO:0006501//C-terminal protein lipidation;GO:0042267//natural killer cell mediated cytotoxicity;GO:0016032//viral process","K07986//UL16 binding protein;K07987//retinoic acid early transcript 1","NP_079493.1//NKG2D ligand 2 preproprotein [Homo sapiens]","3//A2MP1"]
[23659,2764,3.92,5.77,0.557717664530274,0.00152384578363204,"*",0.000441776,"PLA2G15","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0005654//nucleoplasm;GO:0005615//extracellular space;GO:0005764//lysosome;GO:0005576//extracellular region;GO:0005739//mitochondrion","GO:0004622//lysophospholipase activity;GO:0047499//calcium-independent phospholipase A2 activity;GO:0005543//phospholipid binding;GO:0008374//O-acyltransferase activity","GO:0006650//glycerophospholipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0034638//phosphatidylcholine catabolic process;GO:0046338//phosphatidylethanolamine catabolic process;GO:0009062//fatty acid catabolic process;GO:0006629//lipid metabolic process;GO:0006672//ceramide metabolic process","K06129//lysophospholipase III [EC:3.1.1.5]","NP_036452.1//group XV phospholipase A2 precursor [Homo sapiens]","3//A2MP1"]
[57053,2024,0.53,0.78,0.557481764299049,0.440128143004598,"*",0.29363,"CHRNA10","GO:0016020//membrane;GO:0030424//axon;GO:0005892//acetylcholine-gated channel complex;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0045211//postsynaptic membrane;GO:0043204//perikaryon","GO:0005102//receptor binding;GO:0005262//calcium channel activity;GO:0022848//acetylcholine-gated cation-selective channel activity","GO:0007271//synaptic transmission, cholinergic;GO:0042472//inner ear morphogenesis;GO:0050910//detection of mechanical stimulus involved in sensory perception of sound;GO:0042127//regulation of cell proliferation;GO:0007204//positive regulation of cytosolic calcium ion concentration","K04811//nicotinic acetylcholine receptor alpha-10","AAI36251.1//CHRNA10 protein, partial [Homo sapiens];NP_065135.2//neuronal acetylcholine receptor subunit alpha-10 isoform a precursor [Homo sapiens]","1//3;3//A2MP1"]
[2622,3215,8.97,13.2,0.557358039326554,{"v":1.20325240845921e-07,"d":"1.20E-07"},"*",{"v":1.745296e-08,"d":"1.75E-08"},"GAS8","GO:0036126//sperm flagellum;GO:0005929//cilium;GO:0036064//ciliary basal body;GO:0005874//microtubule;GO:0031514//motile cilium;GO:0005794//Golgi apparatus;GO:0005930//axoneme","GO:0017137//Rab GTPase binding;GO:0008017//microtubule binding","GO:0060294//cilium movement involved in cell motility;GO:0030317//flagellated sperm motility;GO:0007368//determination of left/right symmetry;GO:0007420//brain development;GO:0003351//epithelial cilium movement;GO:0048870//cell motility;GO:1904526//regulation of microtubule binding;GO:0035082//axoneme assembly;GO:0034613//cellular protein localization;GO:0008285//negative regulation of cell proliferation","K19942//growth arrest-specific protein 8","NP_001472.1//growth arrest-specific protein 8 isoform a [Homo sapiens]","1//3;2//1"]
[50632,983,0.34,0.5,0.556393348524385,0.66606584317315,"*",0.546646,"CALY","GO:0005768//endosome;GO:0005887//integral component of plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0016021//integral component of membrane;GO:0030659//cytoplasmic vesicle membrane","GO:0032051//clathrin light chain binding;GO:0032403//protein complex binding","GO:0016197//endosomal transport;GO:0048268//clathrin coat assembly;GO:0006897//endocytosis;GO:0045807//positive regulation of endocytosis;GO:0007212//dopamine receptor signaling pathway","K15493//neuron-specific vesicular protein calcyon","NP_001308546.1//neuron-specific vesicular protein calcyon isoform 2 [Homo sapiens];NP_056537.1//neuron-specific vesicular protein calcyon isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[54531,2737,10.67,15.68,0.555365383290783,{"v":6.08473617445483e-08,"d":"6.08E-08"},"*",{"v":8.55916e-09,"d":"8.56E-09"},"MIER2","GO:0005634//nucleus;GO:0043234//protein complex;GO:0005737//cytoplasm","GO:0004407//histone deacetylase activity;GO:0003677//DNA binding;GO:0042826//histone deacetylase binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0016575//histone deacetylation","K11660//metastasis-associated protein MTA;K16912//ribosomal biogenesis protein LAS1","XP_005259639.1//PREDICTED: mesoderm induction early response protein 2 isoform X3 [Homo sapiens];NP_060020.1//mesoderm induction early response protein 2 isoform 1 [Homo sapiens]","1//3;2//1"]
[135154,526,2.79,4.1,0.555358787676258,0.35803276,"*",0.219652,"SDHAF4","GO:0005759//mitochondrial matrix;GO:0005749//mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone);GO:0005739//mitochondrion","GO:0008177//succinate dehydrogenase (ubiquinone) activity","GO:0003407//neural retina development;GO:0034553//mitochondrial respiratory chain complex II assembly;GO:0045333//cellular respiration;GO:0045087//innate immune response","NA","NP_660310.2//succinate dehydrogenase assembly factor 4, mitochondrial precursor [Homo sapiens]","2//1"]
[10500,3923,1.13,1.66,0.554860468931737,0.0605712701471012,"*",0.0262928,"SEMA6C","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane","NA","GO:0007411//axon guidance","K06842//semaphorin 6","NP_001171533.1//semaphorin-6C isoform 3 precursor [Homo sapiens];NP_001171532.1//semaphorin-6C isoform 1 precursor [Homo sapiens];NP_112175.2//semaphorin-6C isoform 2 precursor [Homo sapiens]","1//3;4"]
[3700,3193,0.32,0.47,0.554588851677637,0.440169446321321,"*",0.29363,"ITIH4","GO:0070062//extracellular exosome;GO:0072562//blood microparticle;GO:0031089//platelet dense granule lumen;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0004867//serine-type endopeptidase inhibitor activity;GO:0004866//endopeptidase inhibitor activity","GO:0002576//platelet degranulation;GO:0034097//response to cytokine;GO:0006953//acute-phase response;GO:0030212//hyaluronan metabolic process","K19014//inter-alpha-trypsin inhibitor heavy chain H1;K19015//inter-alpha-trypsin inhibitor heavy chain H2","NP_001159921.1//inter-alpha-trypsin inhibitor heavy chain H4 isoform 2 precursor [Homo sapiens];NP_002209.2//inter-alpha-trypsin inhibitor heavy chain H4 isoform 1 precursor [Homo sapiens]","1//3;4"]
[3037,3275,1.75,2.57,0.554413437361549,0.026845007388576,"*",0.01044458,"HAS2","GO:0005887//integral component of plasma membrane;GO:0005737//cytoplasm","GO:0050501//hyaluronan synthase activity","GO:0030335//positive regulation of cell migration;GO:0001822//kidney development;GO:0071498//cellular response to fluid shear stress;GO:0071356//cellular response to tumor necrosis factor;GO:0044849//estrous cycle;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:1900625//positive regulation of monocyte aggregation;GO:0045226//extracellular polysaccharide biosynthetic process;GO:0090500//endocardial cushion to mesenchymal transition;GO:0071347//cellular response to interleukin-1;GO:0051549//positive regulation of keratinocyte migration;GO:0085029//extracellular matrix assembly;GO:0030213//hyaluronan biosynthetic process;GO:0036120//cellular response to platelet-derived growth factor stimulus;GO:0001570//vasculogenesis;GO:0014911//positive regulation of smooth muscle cell migration;GO:0060349//bone morphogenesis;GO:0070295//renal water absorption;GO:0010838//positive regulation of keratinocyte proliferation;GO:0007155//cell adhesion;GO:1900127//positive regulation of hyaluronan biosynthetic process;GO:0035810//positive regulation of urine volume;GO:1901201//regulation of extracellular matrix assembly;GO:0036302//atrioventricular canal development;GO:0008284//positive regulation of cell proliferation","K00752//hyaluronan synthase [EC:2.4.1.212]","NP_005319.1//hyaluronan synthase 2 [Homo sapiens]","2//1"]
[11007,1277,44.64,65.55,0.554258753279929,{"v":2.49690613617021e-14,"d":"2.50E-14"},"*",{"v":1.83665E-15,"d":"1.84E-15"},"CCDC85B","GO:0005634//nucleus;GO:0005813//centrosome;GO:0005737//cytoplasm","NA","GO:0045892//negative regulation of transcription, DNA-templated;GO:0030308//negative regulation of cell growth;GO:0030154//cell differentiation;GO:0006351//transcription, DNA-templated;GO:0045599//negative regulation of fat cell differentiation","K16758//coiled-coil domain-containing protein 85B","NP_006839.2//coiled-coil domain-containing protein 85B [Homo sapiens]","2//1"]
[5970,2595,61.22,89.87,0.553836557255989,{"v":3.4724506474359e-39,"d":"3.47E-39"},"*",{"v":6.7823e-41,"d":"6.78E-41"},"RELA","GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0005737//cytoplasm;GO:0035525//NF-kappaB p50/p65 complex;GO:0033256//I-kappaB/NF-kappaB complex;GO:0071159//NF-kappaB complex;GO:0005829//cytosol;GO:0005667//transcription factor complex","GO:0003677//DNA binding;GO:0001205//transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0047485//protein N-terminus binding;GO:0031625//ubiquitin protein ligase binding;GO:0046982//protein heterodimerization activity;GO:0031490//chromatin DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0019901//protein kinase binding;GO:0042301//phosphate ion binding;GO:0003682//chromatin binding;GO:0033613//activating transcription factor binding;GO:0003700//DNA binding transcription factor activity;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0042826//histone deacetylase binding;GO:0070491//repressing transcription factor binding;GO:0000983//transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding;GO:0042803//protein homodimerization activity;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0042805//actinin binding;GO:0051059//NF-kappaB binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0071532//ankyrin repeat binding","GO:1902895//positive regulation of pri-miRNA transcription from RNA polymerase II promoter;GO:0071316//cellular response to nicotine;GO:0006117//acetaldehyde metabolic process;GO:0042177//negative regulation of protein catabolic process;GO:0071222//cellular response to lipopolysaccharide;GO:0033234//negative regulation of protein sumoylation;GO:0071347//cellular response to interleukin-1;GO:0071354//cellular response to interleukin-6;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:0070301//cellular response to hydrogen peroxide;GO:0035994//response to muscle stretch;GO:0045084//positive regulation of interleukin-12 biosynthetic process;GO:0035729//cellular response to hepatocyte growth factor stimulus;GO:0071375//cellular response to peptide hormone stimulus;GO:0043620//regulation of DNA-templated transcription in response to stress;GO:1901522//positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:1901223//negative regulation of NIK/NF-kappaB signaling;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0001889//liver development;GO:0032495//response to muramyl dipeptide;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0071223//cellular response to lipoteichoic acid;GO:0070431//nucleotide-binding oligomerization domain containing 2 signaling pathway;GO:0010224//response to UV-B;GO:0006968//cellular defense response;GO:0006954//inflammatory response;GO:0007568//aging;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0050727//regulation of inflammatory response;GO:0071224//cellular response to peptidoglycan;GO:0009887//animal organ morphogenesis;GO:2000630//positive regulation of miRNA metabolic process;GO:0001942//hair follicle development;GO:0050862//positive regulation of T cell receptor signaling pathway;GO:0008284//positive regulation of cell proliferation","K04735//transcription factor p65","NP_001230914.1//transcription factor p65 isoform 4 [Homo sapiens];NP_001138610.1//transcription factor p65 isoform 2 [Homo sapiens];NP_068810.3//transcription factor p65 isoform 1 [Homo sapiens];NP_001230913.1//transcription factor p65 isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[64582,1834,0.75,1.1,0.552541023028779,0.357996229772472,"*",0.219652,"GPR135","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004930//G-protein coupled receptor activity","NA","K08427//G protein-coupled receptor 135","NP_072093.2//probable G-protein coupled receptor 135 [Homo sapiens]",5]
[152756,2197,0.15,0.22,0.552541023028779,0.665659643543223,"*",0.546646,"FAM218A","NA","NA","NA","K12029//tripartite motif-containing protein 60/61","NP_694572.1//protein FAM218A [Homo sapiens]","2//1"]
[728537,1109,0.15,0.22,0.552541023028779,0.780249904829748,"*",0.685686,"C2orf92","NA","NA","NA","NA","NP_001338297.1//uncharacterized protein LOC728537 precursor [Homo sapiens]","1//3"]
[475,498,73.61,107.95,0.552389566932803,{"v":6.20956190553581e-09,"d":"6.21E-09"},"*",{"v":7.65408e-10,"d":"7.65E-10"},"ATOX1","GO:0005623//cell","GO:0032767//copper-dependent protein binding;GO:0016531//copper chaperone activity","GO:0006878//cellular copper ion homeostasis;GO:0006825//copper ion transport","K07213//copper chaperone","XP_012321739.1//copper transport protein ATOX1 [Aotus nancymaae]","3//A2MP1"]
[6891,3981,9.69,14.21,0.552337983827699,{"v":5.29671593767705e-12,"d":"5.30E-12"},"*",{"v":4.68196e-13,"d":"4.68E-13"},"TAP2","GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0016607//nuclear speck;GO:0030670//phagocytic vesicle membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0042825//TAP complex;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0046978//TAP1 binding;GO:0005524//ATP binding;GO:0023029//MHC class Ib protein binding;GO:0042287//MHC protein binding;GO:0015433//peptide antigen-transporting ATPase activity;GO:0015440//peptide-transporting ATPase activity;GO:0046980//tapasin binding;GO:0005215//transporter activity","GO:1990668//vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane;GO:0002489//antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent;GO:0046967//cytosol to ER transport;GO:0016032//viral process;GO:0019885//antigen processing and presentation of endogenous peptide antigen via MHC class I;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0002250//adaptive immune response;GO:0046968//peptide antigen transport;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0015031//protein transport","K05654//ATP-binding cassette, subfamily B (MDR/TAP), member 3","BAD92190.1//transporter 2, ATP-binding cassette, sub-family B isoform 1 variant, partial [Homo sapiens];NP_061313.2//antigen peptide transporter 2 isoform 2 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[125206,2071,3.7,5.42,0.550767580837559,0.0148236616701317,"*",0.00535634,"SLC5A10","GO:0070062//extracellular exosome;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005412//glucose:sodium symporter activity;GO:0005215//transporter activity;GO:0015370//solute:sodium symporter activity","GO:0055085//transmembrane transport;GO:0006814//sodium ion transport;GO:0008645//hexose transport;GO:1904659//glucose transmembrane transport","K14390//solute carrier family 5 (sodium/glucose cotransporter), member 10","XP_016787745.1//PREDICTED: sodium/glucose cotransporter 5 isoform X2 [Pan troglodytes];XP_016787744.1//PREDICTED: sodium/glucose cotransporter 5 isoform X1 [Pan troglodytes];XP_011521955.1//PREDICTED: sodium/glucose cotransporter 5 isoform X3 [Homo sapiens];NP_001257578.1//sodium/glucose cotransporter 5 isoform 4 [Homo sapiens]","4;1//3;2//1"]
[100130933,842,5.53,8.1,0.55064242753728,0.0605800068080196,"*",0.0262928,"SMIM6","GO:0016021//integral component of membrane","NA","NA","NA","NP_001156469.1//small integral membrane protein 6 [Homo sapiens]","1//3"]
[10014,5325,3.68,5.39,0.550579506695492,{"v":1.4076494655717E-5,"d":"1.41E-05"},"*",{"v":2.78992e-06,"d":"2.79E-06"},"HDAC5","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016607//nuclear speck;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0043234//protein complex;GO:0000118//histone deacetylase complex","GO:0004407//histone deacetylase activity;GO:0042826//histone deacetylase binding;GO:0070491//repressing transcription factor binding;GO:0033558//protein deacetylase activity;GO:0032041//NAD-dependent histone deacetylase activity (H3-K14 specific);GO:0046872//metal ion binding;GO:0005080//protein kinase C binding;GO:0001025//RNA polymerase III transcription factor binding;GO:0003682//chromatin binding;GO:0008134//transcription factor binding;GO:0001047//core promoter binding","GO:0090051//negative regulation of cell migration involved in sprouting angiogenesis;GO:0006338//chromatin remodeling;GO:0071222//cellular response to lipopolysaccharide;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0030183//B cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0042493//response to drug;GO:0043393//regulation of protein binding;GO:0040029//regulation of gene expression, epigenetic;GO:0006342//chromatin silencing;GO:0030182//neuron differentiation;GO:0010832//negative regulation of myotube differentiation;GO:0014823//response to activity;GO:0006351//transcription, DNA-templated;GO:0006954//inflammatory response;GO:0032869//cellular response to insulin stimulus;GO:0010830//regulation of myotube differentiation;GO:0006325//chromatin organization;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0042220//response to cocaine;GO:0016575//histone deacetylation;GO:0042113//B cell activation;GO:0006476//protein deacetylation","K11406//histone deacetylase 4/5 [EC:3.5.1.98]","NP_001015053.1//histone deacetylase 5 isoform 3 [Homo sapiens];NP_005465.2//histone deacetylase 5 isoform 1 [Homo sapiens]","4;1//3"]
[2674,9349,0.28,0.41,0.550197082560479,0.222782662220694,"*",0.1217118,"GFRA1","GO:0070062//extracellular exosome;GO:0019898//extrinsic component of membrane;GO:0005622//intracellular;GO:0005886//plasma membrane;GO:0031225//anchored component of membrane","GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0016167//glial cell-derived neurotrophic factor receptor activity;GO:0004872//receptor activity;GO:0005102//receptor binding","GO:0007399//nervous system development;GO:0000165//MAPK cascade;GO:0007166//cell surface receptor signaling pathway;GO:0007411//axon guidance","K19895//GDNF family receptor alpha 1","XP_011715065.1//PREDICTED: GDNF family receptor alpha-1 isoform X2 [Macaca nemestrina];XP_011715075.1//PREDICTED: GDNF family receptor alpha-1 isoform X3 [Macaca nemestrina];NP_005255.1//GDNF family receptor alpha-1 isoform a preproprotein [Homo sapiens]","4;1//3;2//1;5"]
[1848,3385,3.02,4.42,0.549497820066353,2.35635089858687E-3,"*",0.000709826,"DUSP6","GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0017017//MAP kinase tyrosine/serine/threonine phosphatase activity;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity","GO:0014070//response to organic cyclic compound;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0060420//regulation of heart growth;GO:0000188//inactivation of MAPK activity;GO:0043065//positive regulation of apoptotic process;GO:0010942//positive regulation of cell death;GO:0009953//dorsal/ventral pattern formation;GO:0000165//MAPK cascade;GO:0042493//response to drug;GO:0000187//activation of MAPK activity;GO:0030154//cell differentiation;GO:0042663//regulation of endodermal cell fate specification;GO:0051409//response to nitrosative stress;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0070848//response to growth factor;GO:0040036//regulation of fibroblast growth factor receptor signaling pathway","K04459//dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48];K21946//dual specificity phosphatase 6 [EC:3.1.3.16 3.1.3.48]","NP_073143.2//dual specificity protein phosphatase 6 isoform b [Homo sapiens];XP_004845044.2//dual specificity protein phosphatase 6 isoform X1 [Heterocephalus glaber]","3//A2MP1"]
[157777,4947,0.41,0.6,0.549338590990435,0.149303021793921,"*",0.0756516,"MCMDC2","NA","GO:0003677//DNA binding;GO:0005524//ATP binding","GO:0007130//synaptonemal complex assembly;GO:1990918//double-strand break repair involved in meiotic recombination;GO:0048477//oogenesis;GO:0042140//late meiotic recombination nodule assembly;GO:0006270//DNA replication initiation;GO:0007283//spermatogenesis","K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K17985//activating molecule in BECN1-regulated autophagy protein 1;K10738//DNA helicase MCM9 [EC:3.6.4.12]","NP_001129633.1//MCM domain-containing protein 2 isoform c [Homo sapiens];NP_001129632.1//MCM domain-containing protein 2 isoform b [Homo sapiens];NP_775789.3//MCM domain-containing protein 2 isoform a [Homo sapiens]","1//3;4"]
[207063,2596,10.36,15.16,0.549245750484538,{"v":3.06979174267101e-07,"d":"3.07E-07"},"*",{"v":4.7198e-08,"d":"4.72E-08"},"DHRSX","GO:0005576//extracellular region","GO:0016491//oxidoreductase activity","GO:0010508//positive regulation of autophagy","K11170//dehydrogenase/reductase SDR family member X [EC:1.1.-.-]","NP_660160.2//dehydrogenase/reductase SDR family member on chromosome X [Homo sapiens]","2//1"]
[441250,3171,0.67,0.98,0.548620653657436,0.239122088973299,"*",0.1339916,"TYW1B","GO:0016021//integral component of membrane","GO:0102521//tRNA-4-demethylwyosine synthase activity;GO:0046872//metal ion binding;GO:0010181//FMN binding;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0003824//catalytic activity","GO:0055114//oxidation-reduction process;GO:0008033//tRNA processing","K15449//tRNA wybutosine-synthesizing protein 1 [EC:4.1.3.44]","NP_001138912.2//S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase [Homo sapiens]","2//1"]
[49856,1708,8.26,12.08,0.548406767905633,0.000337179727353376,"*",{"v":8.56564e-05,"d":"8.57E-05"},"WRAP73","GO:0036064//ciliary basal body;GO:0005814//centriole;GO:0005813//centrosome","NA","GO:1902857//positive regulation of non-motile cilium assembly;GO:0090307//mitotic spindle assembly;GO:0030030//cell projection organization","NA","NP_060288.3//WD repeat-containing protein WRAP73 [Homo sapiens]","3//A2MP1"]
[3953,3051,7.83,11.45,0.548263385693266,{"v":2.6813669037037e-06,"d":"2.68E-06"},"*",{"v":4.75878e-07,"d":"4.76E-07"},"LEPR","GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0043235//receptor complex","GO:0038021//leptin receptor activity;GO:0042802//identical protein binding;GO:0004888//transmembrane signaling receptor activity","GO:0008203//cholesterol metabolic process;GO:0007166//cell surface receptor signaling pathway;GO:0045721//negative regulation of gluconeogenesis;GO:0042593//glucose homeostasis;GO:0097009//energy homeostasis;GO:0019953//sexual reproduction;GO:0044321//response to leptin;GO:0098868//bone growth;GO:0006112//energy reserve metabolic process;GO:0033210//leptin-mediated signaling pathway;GO:0046850//regulation of bone remodeling;GO:0051346//negative regulation of hydrolase activity;GO:0006909//phagocytosis;GO:0001525//angiogenesis;GO:0060259//regulation of feeding behavior;GO:0007275//multicellular organism development;GO:0010507//negative regulation of autophagy;GO:0030217//T cell differentiation;GO:2000505//regulation of energy homeostasis","K05062//leptin receptor","NP_002294.2//leptin receptor isoform 1 precursor [Homo sapiens];NP_001003679.1//leptin receptor isoform 3 precursor [Homo sapiens];NP_001185617.1//leptin receptor isoform 4 precursor [Homo sapiens];NP_001003680.1//leptin receptor isoform 2 precursor [Homo sapiens]","1//3;3//A2MP1;5"]
[93082,1770,0.52,0.76,0.547487795302493,0.495864713884103,"*",0.3423,"NEURL3","NA","GO:0061630//ubiquitin protein ligase activity;GO:0046872//metal ion binding","NA","K15689//E3 ubiquitin-protein ligase NEURL3 [EC:2.3.2.27]","EAW71368.1//hCG1641111, isoform CRA_a, partial [Homo sapiens];XP_011911136.1//PREDICTED: E3 ubiquitin-protein ligase NEURL3 [Cercocebus atys]","1//3"]
[114299,9500,0.13,0.19,0.547487795302493,0.393221434372875,"*",0.253376,"PALM2","GO:0005886//plasma membrane","NA","GO:0008360//regulation of cell shape","K16519//A-kinase anchor protein 2","XP_003260389.2//PREDICTED: paralemmin-2 isoform X1 [Nomascus leucogenys];NP_001032370.1//paralemmin-2 isoform b [Homo sapiens]","2//1;5"]
[283403,1292,0.13,0.19,0.547487795302493,0.781697699400514,"*",0.685686,"C12orf80","NA","NA","NA","NA","EAW58238.1//hCG2038621, partial [Homo sapiens]","1//3"]
[4584,11361,0.39,0.57,0.547487795302493,0.0744165215735685,"*",0.0332764,"MUC3A","GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005796//Golgi lumen","GO:0005201//extracellular matrix structural constituent;GO:0030197//extracellular matrix constituent, lubricant activity","GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0016266//O-glycan processing","K22016//mucin-3/17","NP_005951.1//mucin-3A precursor [Homo sapiens]","1//3"]
[56624,4700,0.13,0.19,0.547487795302493,0.512037040667923,"*",0.357054,"ASAH2","GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005886//plasma membrane","GO:0017040//ceramidase activity","GO:0007165//signal transduction;GO:0006672//ceramide metabolic process;GO:0006915//apoptotic process","K12349//neutral ceramidase [EC:3.5.1.23]","NP_063946.2//neutral ceramidase isoform a [Homo sapiens];NP_001137446.1//neutral ceramidase isoform b [Homo sapiens]","3//A2MP1;2//1"]
[160140,1274,0.13,0.19,0.547487795302493,0.780138758119658,"*",0.685686,"C11orf65","NA","NA","NA","NA","NP_001338039.1//uncharacterized protein C11orf65 isoform 3 [Homo sapiens];NP_001317297.1//uncharacterized protein C11orf65 isoform 2 [Homo sapiens];NP_689800.3//uncharacterized protein C11orf65 isoform 1 [Homo sapiens]","4;1//3"]
[23710,1885,10.66,15.57,0.546561506319861,{"v":1.50732369230769e-05,"d":"1.51E-05"},"*",{"v":3.0054e-06,"d":"3.01E-06"},"GABARAPL1","GO:0016020//membrane;GO:0032839//dendrite cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005874//microtubule;GO:0005622//intracellular;GO:0044297//cell body;GO:0032590//dendrite membrane;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0005739//mitochondrion;GO:0005776//autophagosome;GO:0000421//autophagosome membrane;GO:0030659//cytoplasmic vesicle membrane","GO:0050811//GABA receptor binding;GO:0048487//beta-tubulin binding;GO:0008092//cytoskeletal protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0030957//Tat protein binding","GO:0097352//autophagosome maturation;GO:0006995//cellular response to nitrogen starvation;GO:0006914//autophagy;GO:0000045//autophagosome assembly;GO:0016236//macroautophagy;GO:0000422//autophagy of mitochondrion","K08341//GABA(A) receptor-associated protein","XP_010984496.1//PREDICTED: gamma-aminobutyric acid receptor-associated protein-like 1 [Camelus dromedarius]","2//1"]
[10848,3121,6.3,9.2,0.546282032557096,{"v":1.60452946941323E-5,"d":"1.60E-05"},"*",{"v":3.2183e-06,"d":"3.22E-06"},"PPP1R13L","GO:0045171//intercellular bridge;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0030054//cell junction","GO:0003714//transcription corepressor activity;GO:0042802//identical protein binding;GO:0008134//transcription factor binding;GO:0045296//cadherin binding","GO:0003229//ventricular cardiac muscle tissue development;GO:0006351//transcription, DNA-templated;GO:0031076//embryonic camera-type eye development;GO:0035264//multicellular organism growth;GO:0006915//apoptotic process;GO:1901796//regulation of signal transduction by p53 class mediator;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0009791//post-embryonic development;GO:0060048//cardiac muscle contraction;GO:0042633//hair cycle;GO:0003215//cardiac right ventricle morphogenesis;GO:0048871//multicellular organismal homeostasis;GO:0045597//positive regulation of cell differentiation","K17554//apoptosis-stimulating of p53 protein 1;K16823//apoptosis-stimulating of p53 protein 2","XP_005589646.1//PREDICTED: relA-associated inhibitor isoform X1 [Macaca fascicularis];XP_512747.4//PREDICTED: relA-associated inhibitor isoform X1 [Pan troglodytes]","1//3;3//A2MP1"]
[115399,2789,0.5,0.73,0.545968369105293,0.358105842825066,"*",0.219652,"LRRC56","NA","NA","NA","K16628//collagen, type VII, alpha;K06236//collagen, type I, alpha","NP_932341.1//leucine-rich repeat-containing protein 56 [Homo sapiens]","3//A2MP1"]
[10957,2133,13.64,19.91,0.54564957669633,{"v":1.2378434060241E-7,"d":"1.24E-07"},"*",{"v":1.800894E-8,"d":"1.80E-08"},"PNRC1","GO:0005634//nucleus;GO:0000932//P-body","NA","GO:0006355//regulation of transcription, DNA-templated;GO:0031087//deadenylation-independent decapping of nuclear-transcribed mRNA;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006351//transcription, DNA-templated","K18774//proline-rich nuclear receptor coactivator 1","NP_006804.1//proline-rich nuclear receptor coactivator 1 [Homo sapiens]","2//1"]
[79005,2051,2.96,4.32,0.545434136534519,0.0298477270211078,"*",0.01177354,"SCNM1","GO:0016607//nuclear speck","GO:0046872//metal ion binding;GO:0019899//enzyme binding","GO:0006397//mRNA processing;GO:0008380//RNA splicing","K12581//CCR4-NOT transcription complex subunit 7/8;K07560//D-tyrosyl-tRNA(Tyr) deacylase [EC:3.1.-.-];K16506//protocadherin Fat 1/2/3;K18047//serine/threonine/tyrosine-interacting-like protein 1;K04487//cysteine desulfurase [EC:2.8.1.7]","XP_011767573.1//PREDICTED: sodium channel modifier 1 [Macaca nemestrina]","1//3;3//A2MP1"]
[138429,1543,1.09,1.59,0.544698630507429,0.344814087764584,"*",0.20906,"PIP5KL1","GO:0016020//membrane;GO:0042995//cell projection;GO:0005829//cytosol","GO:0005524//ATP binding;GO:0016308//1-phosphatidylinositol-4-phosphate 5-kinase activity","NA","K13712//phosphatidylinositol-4-phosphate 5-kinase-like protein 1 [EC:2.7.1.68]","XP_004048716.1//PREDICTED: phosphatidylinositol 4-phosphate 5-kinase-like protein 1 [Gorilla gorilla gorilla];XP_520281.3//PREDICTED: phosphatidylinositol 4-phosphate 5-kinase-like protein 1 isoform X1 [Pan troglodytes]","1//3"]
[4938,1757,12.22,17.82,0.544253051703192,{"v":2.94459482848123e-06,"d":"2.94E-06"},"*",{"v":5.25544e-07,"d":"5.26E-07"},"OAS1","GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005576//extracellular region;GO:0005739//mitochondrion;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0005524//ATP binding;GO:0008270//zinc ion binding;GO:0001730//2'-5'-oligoadenylate synthetase activity;GO:0003725//double-stranded RNA binding","GO:0060333//interferon-gamma-mediated signaling pathway;GO:0006006//glucose metabolic process;GO:0060337//type I interferon signaling pathway;GO:0051607//defense response to virus;GO:0060700//regulation of ribonuclease activity;GO:0042593//glucose homeostasis;GO:0045071//negative regulation of viral genome replication;GO:0006955//immune response;GO:0006164//purine nucleotide biosynthetic process;GO:0009615//response to virus;GO:0035457//cellular response to interferon-alpha;GO:0051259//protein oligomerization","K14216//2'-5'-oligoadenylate synthetase [EC:2.7.7.84]","NP_001126043.1//2'-5'-oligoadenylate synthase 1 [Pongo abelii];NP_001027581.1//2'-5'-oligoadenylate synthase 1 isoform 3 [Homo sapiens];XP_011853298.1//PREDICTED: 2'-5'-oligoadenylate synthase 1 isoform X1 [Mandrillus leucophaeus];XP_011853299.1//PREDICTED: 2'-5'-oligoadenylate synthase 1 isoform X2 [Mandrillus leucophaeus]","1//3;3//A2MP1;2//1"]
[1839,2381,1.75,2.55,0.543142325026529,0.0744050221786614,"*",0.0332666,"HBEGF","GO:0005615//extracellular space;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0030666//endocytic vesicle membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0030669//clathrin-coated endocytic vesicle membrane","GO:0004713//protein tyrosine kinase activity;GO:0008083//growth factor activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0008201//heparin binding;GO:0005154//epidermal growth factor receptor binding;GO:0046934//phosphatidylinositol-4,5-bisphosphate 3-kinase activity","GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0051897//positive regulation of protein kinase B signaling;GO:0030335//positive regulation of cell migration;GO:0030307//positive regulation of cell growth;GO:1901185//negative regulation of ERBB signaling pathway;GO:0008016//regulation of heart contraction;GO:0060326//cell chemotaxis;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0051549//positive regulation of keratinocyte migration;GO:0000165//MAPK cascade;GO:0007165//signal transduction;GO:0014066//regulation of phosphatidylinositol 3-kinase signaling;GO:0038128//ERBB2 signaling pathway;GO:0007517//muscle organ development;GO:2000145//regulation of cell motility;GO:0051545//negative regulation of elastin biosynthetic process;GO:0038111//interleukin-7-mediated signaling pathway;GO:0090303//positive regulation of wound healing;GO:0035313//wound healing, spreading of epidermal cells;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0048015//phosphatidylinositol-mediated signaling;GO:0008284//positive regulation of cell proliferation","K08523//heparin-binding EGF-like growth factor","NP_001936.1//proheparin-binding EGF-like growth factor precursor [Homo sapiens]","2//1"]
[9914,3206,0.11,0.16,0.540568381362703,0.665811910331681,"*",0.546646,"ATP2C2","GO:0031410//cytoplasmic vesicle;GO:0009898//cytoplasmic side of plasma membrane;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm;GO:0000139//Golgi membrane","GO:0046872//metal ion binding;GO:0005524//ATP binding;GO:0005388//calcium-transporting ATPase activity","GO:0090280//positive regulation of calcium ion import;GO:0061180//mammary gland epithelium development;GO:0072659//protein localization to plasma membrane;GO:0034220//ion transmembrane transport","K01537//Ca2+-transporting ATPase [EC:3.6.3.8]","NP_055676.3//calcium-transporting ATPase type 2C member 2 isoform 2 [Homo sapiens];NP_001278383.1//calcium-transporting ATPase type 2C member 2 isoform 3 [Homo sapiens];NP_001273456.2//calcium-transporting ATPase type 2C member 2 isoform 1 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[2022,2817,0.22,0.32,0.540568381362703,0.557608076369001,"*",0.402236,"ENG","GO:0005615//extracellular space;GO:0072563//endothelial microparticle;GO:0009986//cell surface;GO:0009897//external side of plasma membrane;GO:0016021//integral component of membrane","GO:0048185//activin binding;GO:0005114//type II transforming growth factor beta receptor binding;GO:0005539//glycosaminoglycan binding;GO:0050431//transforming growth factor beta binding;GO:0042803//protein homodimerization activity;GO:0005534//galactose binding","GO:0003222//ventricular trabecula myocardium morphogenesis;GO:0003148//outflow tract septum morphogenesis;GO:0097084//vascular smooth muscle cell development;GO:0003198//epithelial to mesenchymal transition involved in endocardial cushion formation;GO:0071260//cellular response to mechanical stimulus;GO:0048745//smooth muscle tissue development;GO:0010629//negative regulation of gene expression;GO:0032967//positive regulation of collagen biosynthetic process;GO:0017015//regulation of transforming growth factor beta receptor signaling pathway;GO:0071559//response to transforming growth factor beta;GO:1905065//positive regulation of vascular smooth muscle cell differentiation;GO:0001934//positive regulation of protein phosphorylation;GO:1905007//positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation;GO:0045766//positive regulation of angiogenesis;GO:0001570//vasculogenesis;GO:0060348//bone development;GO:0042493//response to drug;GO:0035912//dorsal aorta morphogenesis;GO:0030509//BMP signaling pathway;GO:0031960//response to corticosteroid;GO:0055009//atrial cardiac muscle tissue morphogenesis;GO:0001947//heart looping;GO:1905222//atrioventricular canal morphogenesis;GO:0003273//cell migration involved in endocardial cushion formation;GO:0048844//artery morphogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0070278//extracellular matrix constituent secretion;GO:0048845//venous blood vessel morphogenesis;GO:0001569//branching involved in blood vessel morphogenesis;GO:0001300//chronological cell aging","K06526//endoglin","BAF83078.1//unnamed protein product [Homo sapiens];XP_011709764.1//PREDICTED: endoglin [Macaca nemestrina]","1//3;3//A2MP1;2//1"]
[9899,12052,0.55,0.8,0.540568381362703,0.0135909559413203,"*",4.87178E-3,"SV2B","GO:0016020//membrane;GO:0030672//synaptic vesicle membrane;GO:0008021//synaptic vesicle;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0001669//acrosomal vesicle;GO:0005886//plasma membrane","GO:0022857//transmembrane transporter activity","GO:0006836//neurotransmitter transport","K06258//MFS transporter, VNT family, synaptic vesicle glycoprotein 2","XP_020009993.1//synaptic vesicle glycoprotein 2B isoform X2 [Castor canadensis];XP_006905404.1//PREDICTED: synaptic vesicle glycoprotein 2B [Pteropus alecto];NP_055663.1//synaptic vesicle glycoprotein 2B isoform 1 [Homo sapiens];NP_001309962.1//synaptic vesicle glycoprotein 2B isoform 3 [Homo sapiens];NP_001309965.1//synaptic vesicle glycoprotein 2B isoform 5 [Homo sapiens]","6;2//1"]
[9572,2793,8.48,12.33,0.54003662983964,{"v":2.6722236104446e-06,"d":"2.67E-06"},"*",{"v":4.74088e-07,"d":"4.74E-07"},"NR1D1","GO:0030425//dendrite;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0043197//dendritic spine;GO:0000790//nuclear chromatin;GO:0005737//cytoplasm","GO:0003707//steroid hormone receptor activity;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0020037//heme binding;GO:0003714//transcription corepressor activity;GO:0001046//core promoter sequence-specific DNA binding;GO:0001222//transcription corepressor binding;GO:0044212//transcription regulatory region DNA binding;GO:0004879//nuclear receptor activity;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0008270//zinc ion binding;GO:0003700//DNA binding transcription factor activity","GO:0071222//cellular response to lipopolysaccharide;GO:0061469//regulation of type B pancreatic cell proliferation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0044321//response to leptin;GO:0060086//circadian temperature homeostasis;GO:0061178//regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0019216//regulation of lipid metabolic process;GO:0032922//circadian regulation of gene expression;GO:0010498//proteasomal protein catabolic process;GO:0007623//circadian rhythm;GO:0045892//negative regulation of transcription, DNA-templated;GO:0030154//cell differentiation;GO:0045598//regulation of fat cell differentiation;GO:0034144//negative regulation of toll-like receptor 4 signaling pathway;GO:0006351//transcription, DNA-templated;GO:0070859//positive regulation of bile acid biosynthetic process;GO:0042752//regulation of circadian rhythm;GO:0005978//glycogen biosynthetic process;GO:0010871//negative regulation of receptor biosynthetic process;GO:0035947//regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:2000188//regulation of cholesterol homeostasis","K03728//nuclear receptor subfamily 1 group D member 1","NP_068370.1//nuclear receptor subfamily 1 group D member 1 [Homo sapiens]",4]
[25796,1043,55.78,81.06,0.539242241018529,{"v":1.08514545681818E-13,"d":"1.09E-13"},"*",{"v":8.36922e-15,"d":"8.37E-15"},"PGLS","GO:0070062//extracellular exosome;GO:0016021//integral component of membrane","GO:0017057//6-phosphogluconolactonase activity","GO:0006098//pentose-phosphate shunt;GO:0005975//carbohydrate metabolic process","K01057//6-phosphogluconolactonase [EC:3.1.1.31]","XP_003275860.2//PREDICTED: 6-phosphogluconolactonase [Nomascus leucogenys]","2//1"]
[29781,3070,16.76,24.35,0.538899623270353,{"v":5.0945355624355E-17,"d":"5.09E-17"},"*",{"v":3.0904e-18,"d":"3.09E-18"},"NCAPH2","GO:0016020//membrane;GO:0045171//intercellular bridge;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0030054//cell junction;GO:0005694//chromosome","NA","GO:0030261//chromosome condensation","K11490//condensin-2 complex subunit H2","NP_001171940.1//condensin-2 complex subunit H2 isoform 3 [Homo sapiens];NP_689512.2//condensin-2 complex subunit H2 isoform 2 [Homo sapiens];NP_055366.3//condensin-2 complex subunit H2 isoform 1 [Homo sapiens]","1//3;4;3//A2MP1"]
[7746,1683,1.77,2.57,0.53801899911088,0.175092479451725,"*",0.0911634,"ZSCAN9","NA","NA","NA","K09229//KRAB and SCAN domains-containing zinc finger protein;K09230//SCAN domain-containing zinc finger protein","XP_001373597.1//PREDICTED: zinc finger protein with KRAB and SCAN domains 8 isoform X1 [Monodelphis domestica];XP_014589763.1//PREDICTED: zinc finger and SCAN domain-containing protein 23 isoform X2 [Equus caballus]","4;1//3"]
[5176,1337,0.93,1.35,0.5376567859428,0.735413253012048,"*",0.62285,"SERPINF1","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0043203//axon hillock;GO:0005576//extracellular region;GO:0042470//melanosome;GO:0048471//perinuclear region of cytoplasm;GO:0005604//basement membrane","GO:0004867//serine-type endopeptidase inhibitor activity","GO:0060041//retina development in camera-type eye;GO:1901215//negative regulation of neuron death;GO:0001822//kidney development;GO:0010629//negative regulation of gene expression;GO:0050728//negative regulation of inflammatory response;GO:0008283//cell proliferation;GO:0046685//response to arsenic-containing substance;GO:0007614//short-term memory;GO:0042698//ovulation cycle;GO:0016525//negative regulation of angiogenesis;GO:0010596//negative regulation of endothelial cell migration;GO:0010976//positive regulation of neuron projection development;GO:0071279//cellular response to cobalt ion;GO:0007568//aging;GO:0071549//cellular response to dexamethasone stimulus;GO:0071300//cellular response to retinoic acid;GO:0071333//cellular response to glucose stimulus;GO:0050769//positive regulation of neurogenesis;GO:0010447//response to acidic pH;GO:0007275//multicellular organism development;GO:0060770//negative regulation of epithelial cell proliferation involved in prostate gland development","K19614//pigment epithelium-derived factor","XP_008968201.1//PREDICTED: pigment epithelium-derived factor isoform X1 [Pan paniscus];NP_002606.3//pigment epithelium-derived factor isoform 1 precursor [Homo sapiens];AAA93524.1//EPC-1 [Homo sapiens]","6;1//3"]
[440567,538,0.82,1.19,0.53726575868986,0.695478391873589,"*",0.578622,"UQCRHL","GO:0005750//mitochondrial respiratory chain complex III;GO:0005743//mitochondrial inner membrane;GO:0070469//respiratory chain","GO:0008121//ubiquinol-cytochrome-c reductase activity","GO:0009060//aerobic respiration;GO:0006122//mitochondrial electron transport, ubiquinol to cytochrome c","K00416//ubiquinol-cytochrome c reductase subunit 6","XP_003990099.1//PREDICTED: cytochrome b-c1 complex subunit 6, mitochondrial isoform X1 [Felis catus]","1//3"]
[11152,1898,22.85,33.16,0.537249841550318,{"v":1.02677589122807e-10,"d":"1.03E-10"},"*",{"v":1.025876E-11,"d":"1.03E-11"},"WDR45","GO:0019898//extrinsic component of membrane;GO:0005829//cytosol;GO:0034045//phagophore assembly site membrane","GO:0080025//phosphatidylinositol-3,5-bisphosphate binding;GO:0032266//phosphatidylinositol-3-phosphate binding","GO:0034497//protein localization to phagophore assembly site;GO:0006497//protein lipidation;GO:0044804//autophagy of nucleus;GO:0006914//autophagy;GO:0000422//autophagy of mitochondrion","K14810//ATP-dependent RNA helicase DDX56/DBP9 [EC:3.6.4.13];K17908//autophagy-related protein 18","XP_012912999.1//PREDICTED: WD repeat domain phosphoinositide-interacting protein 4 isoform X2 [Mustela putorius furo];XP_004755137.1//PREDICTED: WD repeat domain phosphoinositide-interacting protein 4 isoform X1 [Mustela putorius furo]","1//3;3//A2MP1"]
[4780,2751,42.22,61.25,0.536783265430139,{"v":2.20692693771626E-24,"d":"2.21E-24"},"*",{"v":7.9855e-26,"d":"7.99E-26"},"NFE2L2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000785//chromatin;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0032993//protein-DNA complex;GO:0005886//plasma membrane","GO:0003677//DNA binding;GO:0001205//transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0019904//protein domain specific binding;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0001102//RNA polymerase II activating transcription factor binding","GO:0035690//cellular response to drug;GO:0010499//proteasomal ubiquitin-independent protein catabolic process;GO:1904385//cellular response to angiotensin;GO:0016567//protein ubiquitination;GO:0071356//cellular response to tumor necrosis factor;GO:1902037//negative regulation of hematopoietic stem cell differentiation;GO:0042149//cellular response to glucose starvation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045454//cell redox homeostasis;GO:0071499//cellular response to laminar fluid shear stress;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0046326//positive regulation of glucose import;GO:1903788//positive regulation of glutathione biosynthetic process;GO:0070301//cellular response to hydrogen peroxide;GO:1902176//negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0045995//regulation of embryonic development;GO:0006351//transcription, DNA-templated;GO:0036003//positive regulation of transcription from RNA polymerase II promoter in response to stress;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:0007568//aging;GO:0006954//inflammatory response;GO:0046223//aflatoxin catabolic process;GO:1903206//negative regulation of hydrogen peroxide-induced cell death;GO:2000121//regulation of removal of superoxide radicals;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0034599//cellular response to oxidative stress;GO:0036499//PERK-mediated unfolded protein response;GO:0030194//positive regulation of blood coagulation","K05638//nuclear factor erythroid 2-related factor 2","NP_001300832.1//nuclear factor erythroid 2-related factor 2 isoform 5 [Homo sapiens];NP_001300831.1//nuclear factor erythroid 2-related factor 2 isoform 4 [Homo sapiens];XP_001145876.2//PREDICTED: nuclear factor erythroid 2-related factor 2 isoform X1 [Pan troglodytes];BAD92023.1//nuclear factor (erythroid-derived 2)-like 2 variant, partial [Homo sapiens];NP_001300833.1//nuclear factor erythroid 2-related factor 2 isoform 6 [Homo sapiens];NP_006155.2//nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens]","4;1//3;3//A2MP1"]
[148022,2727,8.95,12.98,0.53633079584752,{"v":2.20445773801002E-6,"d":"2.20E-06"},"*",{"v":3.8558e-07,"d":"3.86E-07"},"TICAM1","GO:0010008//endosome membrane;GO:0005829//cytosol;GO:0097342//ripoptosome;GO:0005776//autophagosome","GO:0004871//signal transducer activity;GO:0019901//protein kinase binding","GO:0032755//positive regulation of interleukin-6 production;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0097190//apoptotic signaling pathway;GO:0071222//cellular response to lipopolysaccharide;GO:0043330//response to exogenous dsRNA;GO:0032092//positive regulation of protein binding;GO:0030890//positive regulation of B cell proliferation;GO:0032760//positive regulation of tumor necrosis factor production;GO:0032816//positive regulation of natural killer cell activation;GO:0043496//regulation of protein homodimerization activity;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0002281//macrophage activation involved in immune response;GO:0045087//innate immune response;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0140052//cellular response to oxidised low-density lipoprotein particle stimulus;GO:0031398//positive regulation of protein ubiquitination;GO:0051607//defense response to virus;GO:0010508//positive regulation of autophagy;GO:0010628//positive regulation of gene expression;GO:0006954//inflammatory response;GO:0034128//negative regulation of MyD88-independent toll-like receptor signaling pathway;GO:0045359//positive regulation of interferon-beta biosynthetic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0045080//positive regulation of chemokine biosynthetic process;GO:0070266//necroptotic process;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:1900017//positive regulation of cytokine production involved in inflammatory response","K05842//toll-like receptor adapter molecule 1","NP_891549.1//TIR domain-containing adapter molecule 1 [Homo sapiens]","3//A2MP1"]
[57820,1366,16.39,23.77,0.536326048842976,{"v":7.24392961021655e-05,"d":"7.24E-05"},"*",{"v":1.633444E-5,"d":"1.63E-05"},"CCNB1IP1","GO:0000795//synaptonemal complex","GO:0061630//ubiquitin protein ligase activity","GO:0007131//reciprocal meiotic recombination;GO:0016567//protein ubiquitination;GO:0007286//spermatid development;GO:0051026//chiasma assembly;GO:0001825//blastocyst formation","K10639//E3 ubiquitin-protein ligase CCNP1IP1 [EC:2.3.2.27]","XP_003811770.1//PREDICTED: E3 ubiquitin-protein ligase CCNB1IP1 isoform X1 [Pan paniscus];XP_002824548.1//PREDICTED: E3 ubiquitin-protein ligase CCNB1IP1 [Pongo abelii]","4;3//A2MP1;2//1"]
[9076,3452,21.06,30.53,0.535722153181063,{"v":3.02248615595363E-17,"d":"3.02E-17"},"*",{"v":1.79563e-18,"d":"1.80E-18"},"CLDN1","GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0005737//cytoplasm;GO:0005887//integral component of plasma membrane;GO:0005923//bicellular tight junction;GO:0016021//integral component of membrane;GO:0016328//lateral plasma membrane;GO:0005886//plasma membrane","GO:0042802//identical protein binding;GO:0005198//structural molecule activity;GO:0001618//virus receptor activity","GO:0097421//liver regeneration;GO:0008065//establishment of blood-nerve barrier;GO:0032496//response to lipopolysaccharide;GO:0051260//protein homooligomerization;GO:0071356//cellular response to tumor necrosis factor;GO:0009636//response to toxic substance;GO:0045471//response to ethanol;GO:0070673//response to interleukin-18;GO:0045216//cell-cell junction organization;GO:0071346//cellular response to interferon-gamma;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;GO:0071548//response to dexamethasone;GO:0051291//protein heterooligomerization;GO:0090557//establishment of endothelial intestinal barrier;GO:0042538//hyperosmotic salinity response;GO:0007568//aging;GO:0071284//cellular response to lead ion;GO:1903348//positive regulation of bicellular tight junction assembly;GO:0070830//bicellular tight junction assembly;GO:0061772//drug transport across blood-nerve barrier;GO:0061436//establishment of skin barrier;GO:1903545//cellular response to butyrate","K06087//claudin","NP_066924.1//claudin-1 [Homo sapiens]",4]
[6672,3153,6.39,9.26,0.535196262313242,0.0053684702816413,"*",0.001744568,"SP100","GO:0016605//PML body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000784//nuclear chromosome, telomeric region;GO:0005737//cytoplasm;GO:0034399//nuclear periphery;GO:0005730//nucleolus;GO:0016604//nuclear body","GO:0070087//chromo shadow domain binding;GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0019904//protein domain specific binding;GO:0003713//transcription coactivator activity;GO:0019900//kinase binding;GO:0008134//transcription factor binding","GO:0060337//type I interferon signaling pathway;GO:0034097//response to cytokine;GO:0043433//negative regulation of DNA binding transcription factor activity;GO:0045185//maintenance of protein location;GO:0045893//positive regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0034340//response to type I interferon;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0034341//response to interferon-gamma;GO:0032897//negative regulation of viral transcription;GO:0046826//negative regulation of protein export from nucleus;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0010596//negative regulation of endothelial cell migration;GO:0048384//retinoic acid receptor signaling pathway;GO:0006351//transcription, DNA-templated;GO:0016032//viral process;GO:0032526//response to retinoic acid;GO:1902044//regulation of Fas signaling pathway;GO:1902041//regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0043392//negative regulation of DNA binding;GO:0045765//regulation of angiogenesis;GO:0000723//telomere maintenance;GO:0051271//negative regulation of cellular component movement;GO:0006978//DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator","K15413//nuclear autoantigen Sp-100","NP_001193632.1//nuclear autoantigen Sp-100 isoform 5 [Homo sapiens];NP_001193630.1//nuclear autoantigen Sp-100 isoform 3 [Homo sapiens];NP_001193633.1//nuclear autoantigen Sp-100 isoform 6 [Homo sapiens];NP_003104.2//nuclear autoantigen Sp-100 isoform 2 [Homo sapiens];NP_001193631.1//nuclear autoantigen Sp-100 isoform 4 [Homo sapiens];NP_001073860.1//nuclear autoantigen Sp-100 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[23208,5298,0.49,0.71,0.535037275389474,0.215971427912341,"*",0.11722,"SYT11","GO:0060076//excitatory synapse;GO:0032009//early phagosome;GO:0030054//cell junction;GO:0048787//presynaptic active zone membrane;GO:0045335//phagocytic vesicle;GO:0005887//integral component of plasma membrane;GO:0030672//synaptic vesicle membrane;GO:0016021//integral component of membrane;GO:0043197//dendritic spine;GO:0055037//recycling endosome;GO:0005886//plasma membrane;GO:0030424//axon;GO:0008021//synaptic vesicle;GO:0098793//presynapse;GO:0005764//lysosome;GO:0043195//terminal bouton;GO:0001891//phagocytic cup;GO:0014069//postsynaptic density;GO:0043005//neuron projection;GO:0048471//perinuclear region of cytoplasm;GO:0044297//cell body;GO:0060077//inhibitory synapse","GO:0000149//SNARE binding;GO:0046872//metal ion binding;GO:0030276//clathrin binding;GO:0048487//beta-tubulin binding;GO:0031625//ubiquitin protein ligase binding;GO:0019905//syntaxin binding;GO:0031369//translation initiation factor binding;GO:0042803//protein homodimerization activity","GO:1905469//negative regulation of clathrin-coated pit assembly;GO:1900424//regulation of defense response to bacterium;GO:0051289//protein homotetramerization;GO:0048791//calcium ion-regulated exocytosis of neurotransmitter;GO:1905154//negative regulation of membrane invagination;GO:1900165//negative regulation of interleukin-6 secretion;GO:1905162//regulation of phagosome maturation;GO:0001778//plasma membrane repair;GO:0006906//vesicle fusion;GO:1990927//calcium ion regulated lysosome exocytosis;GO:1904468//negative regulation of tumor necrosis factor secretion;GO:1905171//positive regulation of protein localization to phagocytic vesicle;GO:0050765//negative regulation of phagocytosis;GO:1900243//negative regulation of synaptic vesicle endocytosis;GO:0046929//negative regulation of neurotransmitter secretion","K19911//synaptotagmin-11","NP_689493.3//synaptotagmin-11 [Homo sapiens]",4]
[5905,3973,45.31,65.65,0.53496552026686,{"v":2.56884183414634e-41,"d":"2.57E-41"},"*",{"v":4.61536e-43,"d":"4.62E-43"},"RANGAP1","NA","GO:0005096//GTPase activator activity","GO:0007165//signal transduction","K14319//Ran GTPase-activating protein 1","XP_003989375.2//PREDICTED: ran GTPase-activating protein 1 isoform X1 [Felis catus]","1//3;3//A2MP1"]
[79641,1776,12.02,17.41,0.534479306939916,{"v":1.28833275658521E-5,"d":"1.29E-05"},"*",{"v":2.54134E-6,"d":"2.54E-06"},"ROGDI","GO:0005635//nuclear envelope;GO:0005622//intracellular","NA","GO:0022008//neurogenesis;GO:0030097//hemopoiesis;GO:0007420//brain development;GO:0008284//positive regulation of cell proliferation;GO:0042475//odontogenesis of dentin-containing tooth","K03006//DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6];K16938//septin 3/9/12;K22022//mucin-21;K17925//sorting nexin-13;K05748//WAS protein family, member 2","NP_078865.1//protein rogdi homolog [Homo sapiens]","2//1"]
[5950,908,7.36,10.66,0.534429766702163,0.0261172836175711,"*",0.01012384,"RBP4","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0043234//protein complex;GO:0005829//cytosol;GO:0005576//extracellular region","GO:0034632//retinol transmembrane transporter activity;GO:0016918//retinal binding;GO:0046982//protein heterodimerization activity;GO:0036094//small molecule binding;GO:0005501//retinoid binding;GO:0005215//transporter activity;GO:0019841//retinol binding","GO:0060044//negative regulation of cardiac muscle cell proliferation;GO:0030324//lung development;GO:0032024//positive regulation of insulin secretion;GO:0060068//vagina development;GO:0060065//uterus development;GO:0048738//cardiac muscle tissue development;GO:0007601//visual perception;GO:0045471//response to ethanol;GO:0042593//glucose homeostasis;GO:0034633//retinol transport;GO:0051024//positive regulation of immunoglobulin secretion;GO:0030277//maintenance of gastrointestinal epithelium;GO:0048807//female genitalia morphogenesis;GO:0001654//eye development;GO:0042572//retinol metabolic process;GO:0006094//gluconeogenesis;GO:0007507//heart development;GO:0048562//embryonic organ morphogenesis;GO:0032526//response to retinoic acid;GO:0060059//embryonic retina morphogenesis in camera-type eye;GO:0001523//retinoid metabolic process;GO:0048706//embryonic skeletal system development;GO:0060347//heart trabecula formation;GO:0060157//urinary bladder development","K18271//retinol-binding protein 4","XP_007961780.1//PREDICTED: retinol-binding protein 4 isoform X1 [Chlorocebus sabaeus];NP_001310447.1//retinol-binding protein 4 isoform b [Homo sapiens]","1//3;3//A2MP1"]
[51257,1570,10.61,15.36,0.533753559806391,0.000313327198512643,"*",{"v":7.91262e-05,"d":"7.91E-05"},"2019-03-02","GO:0005765//lysosomal membrane;GO:0010008//endosome membrane;GO:0005783//endoplasmic reticulum;GO:0031410//cytoplasmic vesicle;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0008270//zinc ion binding;GO:0004842//ubiquitin-protein transferase activity","GO:0016567//protein ubiquitination;GO:0006897//endocytosis","K10657//E3 ubiquitin-protein ligase MARCH2 [EC:2.3.2.27]","XP_012646263.1//E3 ubiquitin-protein ligase MARCH2 isoform X1 [Microcebus murinus];XP_016018568.1//PREDICTED: E3 ubiquitin-protein ligase MARCH2 isoform X10 [Rousettus aegyptiacus]","1//3;4"]
[26232,1724,4.49,6.5,0.53372427317467,0.0133848598810773,"*",0.0047912,"FBXO2","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0043197//dendritic spine;GO:0019005//SCF ubiquitin ligase complex","GO:0030246//carbohydrate binding;GO:0001540//amyloid-beta binding","GO:0031396//regulation of protein ubiquitination;GO:0006516//glycoprotein catabolic process;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination","K10099//F-box protein 2","XP_004596100.1//PREDICTED: F-box only protein 2 isoform X2 [Ochotona princeps]",5]
[5936,1576,106.18,153.67,0.533323497923029,{"v":1.74967141741425E-33,"d":"1.75E-33"},"*",{"v":4.15128e-35,"d":"4.15E-35"},"RBM4","GO:0010494//cytoplasmic stress granule;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0097157//pre-mRNA intronic binding;GO:0003730//mRNA 3'-UTR binding;GO:0036002//pre-mRNA binding;GO:0097158//pre-mRNA intronic pyrimidine-rich binding;GO:0035198//miRNA binding;GO:0008270//zinc ion binding;GO:0030332//cyclin binding","GO:0006396//RNA processing;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0002192//IRES-dependent translational initiation of linear mRNA;GO:0045947//negative regulation of translational initiation;GO:0097167//circadian regulation of translation;GO:0017148//negative regulation of translation;GO:0046685//response to arsenic-containing substance;GO:0043153//entrainment of circadian clock by photoperiod;GO:0006397//mRNA processing;GO:0030154//cell differentiation;GO:0046822//regulation of nucleocytoplasmic transport;GO:0002190//cap-independent translational initiation;GO:0051149//positive regulation of muscle cell differentiation;GO:0032055//negative regulation of translation in response to stress;GO:0008380//RNA splicing;GO:0035278//miRNA mediated inhibition of translation","K13187//RNA-binding protein 4","EPQ06579.1//RNA-binding protein 14 [Myotis brandtii];XP_021541240.1//RNA-binding protein 4 isoform X2 [Neomonachus schauinslandi];NP_001185773.1//RNA-binding protein 4 isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[55168,1207,33.74,48.83,0.533307804349898,{"v":1.0842692278453e-09,"d":"1.08E-09"},"*",{"v":1.228576e-10,"d":"1.23E-10"},"MRPS18A","GO:0005763//mitochondrial small ribosomal subunit;GO:0005743//mitochondrial inner membrane;GO:0022627//cytosolic small ribosomal subunit","GO:0003735//structural constituent of ribosome","GO:0032543//mitochondrial translation;GO:0006412//translation;GO:0070126//mitochondrial translational termination;GO:0070125//mitochondrial translational elongation","K02963//small subunit ribosomal protein S18","XP_007458338.1//PREDICTED: 28S ribosomal protein S18a, mitochondrial isoform X2 [Lipotes vexillifer];NP_060605.1//39S ribosomal protein S18a, mitochondrial isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[27201,4262,0.47,0.68,0.532873989572702,0.276758740425532,"*",0.1596032,"GPR78","GO:0005622//intracellular;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004930//G-protein coupled receptor activity","GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway","K08418//G protein-coupled receptor 78","NP_543009.2//G-protein coupled receptor 78 [Homo sapiens]",4]
[84063,2860,0.56,0.81,0.532495080827021,0.332738486475239,"*",0.200218,"KIRREL2","GO:0016021//integral component of membrane;GO:0036057//slit diaphragm;GO:0005886//plasma membrane","NA","GO:0098609//cell-cell adhesion;GO:0007155//cell adhesion;GO:0001933//negative regulation of protein phosphorylation","K17341//hemicentin;K18273//alpha-tectorin","NP_954648.3//kin of IRRE-like protein 2 isoform b precursor [Homo sapiens];NP_001316459.1//kin of IRRE-like protein 2 isoform d precursor [Homo sapiens];XP_004089244.1//PREDICTED: kin of IRRE-like protein 2 isoform X1 [Nomascus leucogenys];NP_115499.5//kin of IRRE-like protein 2 isoform a precursor [Homo sapiens]","6;1//3;3//A2MP1"]
[4647,7339,0.65,0.94,0.532221038649183,0.0626758339167862,"*",0.0273476,"MYO7A","GO:0005765//lysosomal membrane;GO:0001917//photoreceptor inner segment;GO:0005938//cell cortex;GO:0016324//apical plasma membrane;GO:0032391//photoreceptor connecting cilium;GO:1990435//upper tip-link density;GO:0042470//melanosome;GO:0001750//photoreceptor outer segment;GO:0005902//microvillus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0032420//stereocilium;GO:0031477//myosin VII complex;GO:0045202//synapse","GO:0051015//actin filament binding;GO:0005524//ATP binding;GO:0047485//protein N-terminus binding;GO:0042803//protein homodimerization activity;GO:0043531//ADP binding;GO:0019904//protein domain specific binding;GO:0000146//microfilament motor activity;GO:0005516//calmodulin binding;GO:0030898//actin-dependent ATPase activity;GO:0030507//spectrin binding","GO:0030048//actin filament-based movement;GO:0060088//auditory receptor cell stereocilium organization;GO:0007601//visual perception;GO:0006886//intracellular protein transport;GO:0050957//equilibrioception;GO:0001845//phagolysosome assembly;GO:0007605//sensory perception of sound;GO:0050953//sensory perception of light stimulus;GO:0051904//pigment granule transport;GO:0048563//post-embryonic animal organ morphogenesis;GO:0042462//eye photoreceptor cell development;GO:0007040//lysosome organization","K10359//myosin VIIa","NP_001120652.1//unconventional myosin-VIIa isoform 2 [Homo sapiens];NP_000251.3//unconventional myosin-VIIa isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[11217,6815,4.73,6.84,0.532156141546503,{"v":5.86873910813226e-08,"d":"5.87E-08"},"*",{"v":8.22226e-09,"d":"8.22E-09"},"AKAP2","NA","NA","NA","K16519//A-kinase anchor protein 2","NP_001004065.2//A-kinase anchor protein 2 isoform 1 [Homo sapiens];NP_001185585.1//A-kinase anchor protein 2 isoform 3 [Homo sapiens];NP_671492.1//PALM2-AKAP2 protein isoform 2 [Homo sapiens]","1//3;4;2//1"]
[8336,487,0.74,1.07,0.532013620772197,0.665913460230306,"*",0.546646,"HIST1H2AM","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0000786//nucleosome","GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity;GO:0019899//enzyme binding","GO:0006342//chromatin silencing;GO:0006334//nucleosome assembly;GO:0006352//DNA-templated transcription, initiation","K11251//histone H2A;K11254//histone H4","XP_011931511.1//PREDICTED: uncharacterized protein LOC105593202 [Cercocebus atys]","2//1"]
[10616,1964,106.83,154.47,0.532009834434394,{"v":1.80210114992126E-77,"d":"1.80E-77"},"*",{"v":1.432746e-79,"d":"1.43E-79"},"RBCK1","GO:0071797//LUBAC complex;GO:0005829//cytosol","GO:0043130//ubiquitin binding;GO:0046872//metal ion binding;GO:0004842//ubiquitin-protein transferase activity","GO:0050852//T cell receptor signaling pathway;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0060546//negative regulation of necroptotic process;GO:0016032//viral process;GO:0010803//regulation of tumor necrosis factor-mediated signaling pathway;GO:0042346//positive regulation of NF-kappaB import into nucleus;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0000209//protein polyubiquitination;GO:0097039//protein linear polyubiquitination","K10630//RanBP-type and C3HC4-type zinc finger-containing protein 1 [EC:2.3.2.27]","NP_006453.1//ranBP-type and C3HC4-type zinc finger-containing protein 1 isoform 1 [Homo sapiens];NP_001310885.1//ranBP-type and C3HC4-type zinc finger-containing protein 1 isoform 3 [Homo sapiens];NP_112506.2//ranBP-type and C3HC4-type zinc finger-containing protein 1 isoform 2 [Homo sapiens];XP_017800410.1//ranBP-type and C3HC4-type zinc finger-containing protein 1 isoform X5 [Papio anubis]","1//3;3//A2MP1;5"]
[8530,940,0.18,0.26,0.53051471669878,0.782367726,"*",0.685686,"CST7","NA","GO:0004869//cysteine-type endopeptidase inhibitor activity","NA","K13903//cystatin-F","BAA34941.1//human CMAP [Homo sapiens]","3//A2MP1"]
[1803,3913,0.18,0.26,0.53051471669878,0.557511311409978,"*",0.402236,"DPP4","GO:0016020//membrane;GO:0005765//lysosomal membrane;GO:0070062//extracellular exosome;GO:0005925//focal adhesion;GO:0016324//apical plasma membrane;GO:0046581//intercellular canaliculus;GO:0030027//lamellipodium;GO:0031258//lamellipodium membrane;GO:0071438//invadopodium membrane;GO:0009986//cell surface;GO:0045121//membrane raft;GO:0030139//endocytic vesicle;GO:0005576//extracellular region;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004252//serine-type endopeptidase activity;GO:0002020//protease binding;GO:0042802//identical protein binding;GO:0005102//receptor binding;GO:0042803//protein homodimerization activity;GO:0008236//serine-type peptidase activity;GO:0008239//dipeptidyl-peptidase activity;GO:0001618//virus receptor activity","GO:0042110//T cell activation;GO:0033632//regulation of cell-cell adhesion mediated by integrin;GO:0043542//endothelial cell migration;GO:0035641//locomotory exploration behavior;GO:0031295//T cell costimulation;GO:0001666//response to hypoxia;GO:0050796//regulation of insulin secretion;GO:0001662//behavioral fear response;GO:0007155//cell adhesion;GO:0010716//negative regulation of extracellular matrix disassembly;GO:0036343//psychomotor behavior;GO:0008284//positive regulation of cell proliferation","K01278//dipeptidyl-peptidase 4 [EC:3.4.14.5]","NP_001926.2//dipeptidyl peptidase 4 [Homo sapiens]","3//A2MP1"]
[220382,1875,0.09,0.13,0.53051471669878,0.7806948085531,"*",0.685686,"FAM181B","NA","NA","NA","K13172//serine/arginine repetitive matrix protein 2;K13171//serine/arginine repetitive matrix protein 1","NP_787081.2//protein FAM181B [Homo sapiens]","3//A2MP1"]
[10630,2818,0.09,0.13,0.53051471669878,0.81027169892172,"*",0.724446,"PDPN","GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0042995//cell projection;GO:0009897//external side of plasma membrane;GO:0016324//apical plasma membrane;GO:0097197//tetraspanin-enriched microdomain;GO:0071437//invadopodium;GO:0031410//cytoplasmic vesicle;GO:0030054//cell junction;GO:0032587//ruffle membrane;GO:0005887//integral component of plasma membrane;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0031527//filopodium membrane;GO:0030027//lamellipodium;GO:0030175//filopodium;GO:0001726//ruffle;GO:0031258//lamellipodium membrane;GO:0061851//leading edge of lamellipodium;GO:0045121//membrane raft;GO:0031528//microvillus membrane","GO:0019956//chemokine binding;GO:0005102//receptor binding;GO:0051087//chaperone binding","GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:0030324//lung development;GO:1904328//regulation of myofibroblast contraction;GO:0030335//positive regulation of cell migration;GO:0070252//actin-mediated cell contraction;GO:0030168//platelet activation;GO:0098609//cell-cell adhesion;GO:0060838//lymphatic endothelial cell fate commitment;GO:0008283//cell proliferation;GO:0051272//positive regulation of cellular component movement;GO:1905863//invadopodium organization;GO:1901731//positive regulation of platelet aggregation;GO:0044319//wound healing, spreading of cells;GO:0008285//negative regulation of cell proliferation;GO:0000902//cell morphogenesis;GO:0048535//lymph node development;GO:0043066//negative regulation of apoptotic process;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0008360//regulation of cell shape;GO:0090091//positive regulation of extracellular matrix disassembly;GO:1900024//regulation of substrate adhesion-dependent cell spreading;GO:0007266//Rho protein signal transduction;GO:0006693//prostaglandin metabolic process;GO:2000392//regulation of lamellipodium morphogenesis;GO:0048286//lung alveolus development;GO:0001946//lymphangiogenesis","K16778//podoplanin","NP_006465.3//podoplanin isoform a [Homo sapiens];NP_938203.2//podoplanin isoform b [Homo sapiens]","4;1//3;2//1"]
[11105,3284,0.27,0.39,0.53051471669878,0.495819749727965,"*",0.3423,"PRDM7","GO:0005634//nucleus;GO:0005694//chromosome","GO:0003676//nucleic acid binding;GO:0018024//histone-lysine N-methyltransferase activity","GO:0006355//regulation of transcription, DNA-templated","K20796//histone-lysine N-methyltransferase PRDM7/9 [EC:2.1.1.43]","NP_001091643.1//probable histone-lysine N-methyltransferase PRDM7 [Homo sapiens]","1//3"]
[375775,4780,0.45,0.65,0.53051471669878,0.247697899601064,"*",0.139929,"PNPLA7","GO:0005765//lysosomal membrane;GO:0031965//nuclear membrane;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane","GO:0004622//lysophospholipase activity","GO:0032502//developmental process;GO:0016042//lipid catabolic process","K14676//lysophospholipid hydrolase [EC:3.1.1.5]","NP_689499.4//patatin-like phospholipase domain-containing protein 7 isoform b [Homo sapiens];NP_001092007.2//patatin-like phospholipase domain-containing protein 7 isoform a [Homo sapiens]","4;2//1"]
[6274,738,69.91,100.92,0.529641371335296,{"v":1.39285466630435e-11,"d":"1.39E-11"},"*",{"v":1.283512E-12,"d":"1.28E-12"},"S100A3","NA","NA","NA","NA","XP_007975266.1//PREDICTED: protein S100-A3 isoform X1 [Chlorocebus sabaeus]","1//3"]
[1238,2978,0.97,1.4,0.529370174757839,0.169331357822142,"*",0.0876126,"ACKR2","GO:0043231//intracellular membrane-bounded organelle;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0005884//actin filament;GO:0005887//integral component of plasma membrane;GO:0005829//cytosol;GO:0055037//recycling endosome;GO:0005769//early endosome;GO:0005886//plasma membrane","GO:0005044//scavenger receptor activity;GO:0016493//C-C chemokine receptor activity;GO:0019957//C-C chemokine binding;GO:0004950//chemokine receptor activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0007275//multicellular organism development;GO:0006955//immune response;GO:0006935//chemotaxis;GO:0006954//inflammatory response","K04187//chemokine binding protein 2","XP_002813926.1//PREDICTED: atypical chemokine receptor 2 [Pongo abelii]",4]
[283643,1694,15.16,21.88,0.529342984621465,{"v":2.20661806940966e-06,"d":"2.21E-06"},"*",{"v":3.86096e-07,"d":"3.86E-07"},"TEDC1","NA","NA","NA","K22022//mucin-21;K19475//WAS/WASL-interacting protein;K19720//collagen, type III, alpha;K20638//Rho GTPase-activating protein 17","CAD62351.1//unnamed protein product, partial [Homo sapiens];CAD62611.1//unnamed protein product, partial [Homo sapiens];NP_001128347.1//uncharacterized protein C14orf80 isoform 1 [Homo sapiens]","1//3"]
[64374,1908,11.42,16.47,0.528277904363512,{"v":1.61494848034935E-5,"d":"1.61E-05"},"*",{"v":3.24122e-06,"d":"3.24E-06"},"SIL1","GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum","GO:0051082//unfolded protein binding","GO:0006457//protein folding;GO:0006886//intracellular protein transport","K14001//nucleotide exchange factor SIL1","XP_011541872.1//PREDICTED: nucleotide exchange factor SIL1 isoform X1 [Homo sapiens]","1//3;4"]
[7425,2586,7.56,10.9,0.527869995443216,{"v":4.0037215132948e-05,"d":"4.00E-05"},"*",{"v":8.67214e-06,"d":"8.67E-06"},"VGF","GO:0043231//intracellular membrane-bounded organelle;GO:0005615//extracellular space;GO:0031410//cytoplasmic vesicle","GO:0005184//neuropeptide hormone activity;GO:0005179//hormone activity","GO:0032868//response to insulin;GO:0009409//response to cold;GO:0051591//response to cAMP;GO:0006091//generation of precursor metabolites and energy;GO:0002021//response to dietary excess;GO:0001541//ovarian follicle development;GO:0030073//insulin secretion;GO:0042593//glucose homeostasis;GO:0019953//sexual reproduction;GO:0033500//carbohydrate homeostasis;GO:0048167//regulation of synaptic plasticity","K19720//collagen, type III, alpha","XP_011758272.1//PREDICTED: LOW QUALITY PROTEIN: neurosecretory protein VGF [Macaca nemestrina]","3//A2MP1"]
[3399,1252,342.57,493.71,0.527265051555855,{"v":1.19480094867925E-92,"d":"1.19E-92"},"*",{"v":7.92844e-95,"d":"7.93E-95"},"ID3","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0046983//protein dimerization activity","GO:0045892//negative regulation of transcription, DNA-templated","K17694//DNA-binding protein inhibitor ID3","CAA47360.1//helix-loop-helix protein [Homo sapiens]",4]
[80194,928,29.52,42.53,0.526788133565368,{"v":1.2266034506885E-6,"d":"1.23E-06"},"*",{"v":2.06328e-07,"d":"2.06E-07"},"TMEM134","GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm","NA","NA","K22020//mucin-19","XP_007963790.1//PREDICTED: transmembrane protein 134 isoform X2 [Chlorocebus sabaeus];XP_007963728.1//PREDICTED: transmembrane protein 134 isoform X1 [Chlorocebus sabaeus]","3//A2MP1;2//1"]
[83853,974,0.59,0.85,0.52674788677586,0.512083012749147,"*",0.357054,"ROPN1L","GO:0031514//motile cilium;GO:0005737//cytoplasm","NA","GO:0001932//regulation of protein phosphorylation;GO:0030317//flagellated sperm motility;GO:0048240//sperm capacitation;GO:0003351//epithelial cilium movement","NA","NP_114122.2//ropporin-1-like protein [Homo sapiens]","1//3;4"]
[84993,1350,30.27,43.6,0.526439459836775,{"v":3.26762264705882e-09,"d":"3.27E-09"},"*",{"v":3.8948e-10,"d":"3.89E-10"},"UBL7","NA","NA","NA","K04523//ubiquilin","XP_003363698.2//PREDICTED: ubiquitin-like protein 7 isoform X1 [Equus caballus];NP_001273671.1//ubiquitin-like protein 7 isoform b [Homo sapiens];XP_009427813.2//PREDICTED: ubiquitin-like protein 7 isoform X1 [Pan troglodytes];KFO37988.1//Ubiquitin-like protein 7 [Fukomys damarensis];XP_008014084.1//PREDICTED: ubiquitin-like protein 7 isoform X4 [Chlorocebus sabaeus]","4;1//3"]
[4004,1008,2.68,3.86,0.526367846810308,0.209030882025081,"*",0.112694,"LMO1","GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0046872//metal ion binding","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:1902036//regulation of hematopoietic stem cell differentiation;GO:0046013//regulation of T cell homeostatic proliferation","K15612//rhombotin-2","AAH39512.1//LIM domain only 1 (rhombotin 1), partial [Homo sapiens];EFB17284.1//hypothetical protein PANDA_004271, partial [Ailuropoda melanoleuca]","1//3;2//1"]
[84065,1629,28.6,41.18,0.525928682966502,{"v":9.08715392443325e-11,"d":"9.09E-11"},"*",{"v":9.03368e-12,"d":"9.03E-12"},"TMEM222","GO:0016021//integral component of membrane","NA","NA","K20726//transmembrane protein 222","NP_115501.2//transmembrane protein 222 [Homo sapiens]","2//1"]
[51259,1295,9.49,13.66,0.525477491268981,0.00175874864689567,"*",0.000516042,"TMEM216","GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0036038//MKS complex","NA","GO:0060271//cilium assembly;GO:0097711//ciliary basal body-plasma membrane docking","K19385//transmembrane protein 216","XP_003274085.1//PREDICTED: transmembrane protein 216 isoform X1 [Nomascus leucogenys];XP_012351755.1//PREDICTED: transmembrane protein 216 isoform X2 [Nomascus leucogenys]","1//3;2//1;5"]
[403312,3421,0.66,0.95,0.525461488972494,0.256280829932871,"*",0.1457884,"LOC403312","NA","NA","NA","K15696//RING finger protein 113B;K01064//wingless-type MMTV integration site family, member 9","XP_011908665.1//PREDICTED: LOW QUALITY PROTEIN: putative uncharacterized protein MGC39545 [Cercocebus atys]","1//3"]
[9052,2856,41.41,59.59,0.525091044743758,{"v":2.77200090810811e-26,"d":"2.77E-26"},"*",{"v":8.98896e-28,"d":"8.99E-28"},"GPRC5A","GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0005730//nucleolus;GO:0005887//integral component of plasma membrane;GO:0031982//vesicle;GO:0005886//plasma membrane;GO:0030659//cytoplasmic vesicle membrane","GO:0004930//G-protein coupled receptor activity;GO:0045296//cadherin binding","GO:0007165//signal transduction;GO:0007175//negative regulation of epidermal growth factor-activated receptor activity","K08468//G protein-coupled receptor family C group 5 member A","NP_003970.1//retinoic acid-induced protein 3 [Homo sapiens]","3//A2MP1"]
[2954,1395,13.92,20.02,0.524282762987265,{"v":8.17300972499311e-05,"d":"8.17E-05"},"*",{"v":1.856758E-5,"d":"1.86E-05"},"GSTZ1","GO:0005829//cytosol;GO:0005739//mitochondrion","GO:0004364//glutathione transferase activity;GO:0016853//isomerase activity;GO:0042802//identical protein binding;GO:0004602//glutathione peroxidase activity;GO:0016740//transferase activity;GO:0016034//maleylacetoacetate isomerase activity;GO:0042803//protein homodimerization activity","GO:0009072//aromatic amino acid family metabolic process;GO:0006572//tyrosine catabolic process;GO:0006749//glutathione metabolic process;GO:0006559//L-phenylalanine catabolic process;GO:1901687//glutathione derivative biosynthetic process","K01800//maleylacetoacetate isomerase [EC:5.2.1.2]","NP_665877.1//maleylacetoacetate isomerase isoform 1 [Homo sapiens];NP_665878.2//maleylacetoacetate isomerase isoform 2 [Homo sapiens]","1//3;2//1"]
[8347,438,0.89,1.28,0.524266569033602,0.666218295872435,"*",0.546646,"HIST1H2BC","NA","NA","NA","K11252//histone H2B","EDL84564.1//histone 1, H2bn (predicted) [Rattus norvegicus]","2//1"]
[6158,1502,496.8,714.45,0.524167875864697,{"v":5.25246051448276e-147,"d":"5.25E-147"},"*",{"v":1.907116e-149,"d":"1.91E-149"},"RPL28","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0030425//dendrite;GO:0044297//cell body;GO:0005829//cytosol;GO:0022625//cytosolic large ribosomal subunit;GO:0036464//cytoplasmic ribonucleoprotein granule","GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome","GO:1903955//positive regulation of protein targeting to mitochondrion;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:1903146//regulation of autophagy of mitochondrion;GO:0006364//rRNA processing;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006413//translational initiation;GO:0006412//translation;GO:0019083//viral transcription","K02903//large subunit ribosomal protein L28e","XP_017502729.1//PREDICTED: 60S ribosomal protein L28 isoform X3 [Manis javanica];NP_001129606.1//60S ribosomal protein L28 isoform 1 [Homo sapiens];BAD92864.1//ribosomal protein L28 variant, partial [Homo sapiens];NP_001129607.1//60S ribosomal protein L28 isoform 3 [Homo sapiens]","4;1//3"]
[6648,3764,34.53,49.64,0.52365278127697,{"v":2.49578620440529e-50,"d":"2.50E-50"},"*",{"v":3.54666e-52,"d":"3.55E-52"},"SOD2","GO:0005759//mitochondrial matrix;GO:0070062//extracellular exosome;GO:0042645//mitochondrial nucleoid;GO:0043209//myelin sheath;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0004784//superoxide dismutase activity;GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0042802//identical protein binding;GO:0019825//oxygen binding;GO:0019899//enzyme binding;GO:0030145//manganese ion binding","GO:0006801//superoxide metabolic process;GO:0008217//regulation of blood pressure;GO:0000303//response to superoxide;GO:0030335//positive regulation of cell migration;GO:0034021//response to silicon dioxide;GO:0051260//protein homooligomerization;GO:0010332//response to gamma radiation;GO:0048666//neuron development;GO:0055072//iron ion homeostasis;GO:0022904//respiratory electron transport chain;GO:0009791//post-embryonic development;GO:0003032//detection of oxygen;GO:0071000//response to magnetism;GO:0033591//response to L-ascorbic acid;GO:0008285//negative regulation of cell proliferation;GO:0071361//cellular response to ethanol;GO:0019430//removal of superoxide radicals;GO:0042493//response to drug;GO:0051289//protein homotetramerization;GO:0007507//heart development;GO:0043524//negative regulation of neuron apoptotic process;GO:0010043//response to zinc ion;GO:0045599//negative regulation of fat cell differentiation;GO:0043066//negative regulation of apoptotic process;GO:0048147//negative regulation of fibroblast proliferation;GO:0035902//response to immobilization stress;GO:0001666//response to hypoxia;GO:0007005//mitochondrion organization;GO:0010042//response to manganese ion;GO:0046686//response to cadmium ion;GO:0006749//glutathione metabolic process;GO:0001315//age-dependent response to reactive oxygen species;GO:0034599//cellular response to oxidative stress;GO:0055093//response to hyperoxia;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0048773//erythrophore differentiation;GO:0032496//response to lipopolysaccharide;GO:0032364//oxygen homeostasis;GO:0051602//response to electrical stimulus;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0010269//response to selenium ion;GO:0042554//superoxide anion generation;GO:0030097//hemopoiesis;GO:0035722//interleukin-12-mediated signaling pathway;GO:0001836//release of cytochrome c from mitochondria;GO:1902176//negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0001889//liver development;GO:0009409//response to cold;GO:0048678//response to axon injury;GO:0014823//response to activity;GO:0008631//intrinsic apoptotic signaling pathway in response to oxidative stress;GO:0042542//response to hydrogen peroxide;GO:0050790//regulation of catalytic activity;GO:0035900//response to isolation stress;GO:0007626//locomotory behavior;GO:0051881//regulation of mitochondrial membrane potential;GO:0003069//acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure;GO:0001306//age-dependent response to oxidative stress;GO:0050665//hydrogen peroxide biosynthetic process","K04564//superoxide dismutase, Fe-Mn family [EC:1.15.1.1]","NP_001019637.1//superoxide dismutase [Mn], mitochondrial isoform B [Homo sapiens];NP_000627.2//superoxide dismutase [Mn], mitochondrial isoform A precursor [Homo sapiens];NP_001309744.1//superoxide dismutase [Mn], mitochondrial isoform C precursor [Homo sapiens];NP_001309745.1//superoxide dismutase [Mn], mitochondrial isoform D [Homo sapiens]","1//3;3//A2MP1;2//1"]
[648791,1745,0.32,0.46,0.523561956057013,0.634421781026749,"*",0.4781,"PPP1R3G","NA","NA","NA","K07189//protein phosphatase 1 regulatory subunit 3A/B/C/D/E","NP_001138587.1//protein phosphatase 1 regulatory subunit 3G [Homo sapiens]","2//1"]
[9071,2490,0.16,0.23,0.523561956057013,0.695426064855918,"*",0.578622,"CLDN10","GO:0016021//integral component of membrane;GO:0005923//bicellular tight junction;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0042802//identical protein binding;GO:0005198//structural molecule activity","GO:0007155//cell adhesion;GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;GO:0006811//ion transport","K06087//claudin","NP_008915.1//claudin-10 isoform b precursor [Homo sapiens];EAX08953.1//hCG2039317, partial [Homo sapiens]","4;1//3;3//A2MP1"]
[1496,3870,0.16,0.23,0.523561956057013,0.640977714514707,"*",0.500656,"CTNNA2","GO:0016323//basolateral plasma membrane;GO:0030424//axon;GO:0005634//nucleus;GO:0014069//postsynaptic density;GO:0030027//lamellipodium;GO:0005737//cytoplasm;GO:0005912//adherens junction;GO:0005913//cell-cell adherens junction;GO:0005829//cytosol;GO:0015629//actin cytoskeleton","GO:0051015//actin filament binding;GO:0042802//identical protein binding;GO:0005198//structural molecule activity;GO:0005200//structural constituent of cytoskeleton;GO:0045296//cadherin binding","GO:0048854//brain morphogenesis;GO:0051823//regulation of synapse structural plasticity;GO:0060134//prepulse inhibition;GO:0021942//radial glia guided migration of Purkinje cell;GO:0048813//dendrite morphogenesis;GO:0007409//axonogenesis;GO:0098609//cell-cell adhesion;GO:0007155//cell adhesion;GO:0051149//positive regulation of muscle cell differentiation","K05691//catenin alpha","XP_012503919.1//PREDICTED: catenin alpha-2 isoform X2 [Propithecus coquereli];NP_001269527.1//catenin alpha-2 isoform 4 [Homo sapiens];XP_012503918.1//PREDICTED: catenin alpha-2 isoform X1 [Propithecus coquereli];NP_001158355.1//catenin alpha-2 isoform 2 [Homo sapiens];NP_001269528.1//catenin alpha-2 isoform 5 [Homo sapiens];XP_004090482.2//PREDICTED: catenin alpha-2 isoform X1 [Nomascus leucogenys];XP_017392184.1//PREDICTED: catenin alpha-2 isoform X5 [Cebus capucinus imitator]","1//3;3//A2MP1;2//1"]
[10025,2952,10.36,14.89,0.523319750895546,{"v":2.10659540759282e-07,"d":"2.11E-07"},"*",{"v":3.16108E-8,"d":"3.16E-08"},"MED16","GO:0016020//membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016592//mediator complex","GO:0042809//vitamin D receptor binding;GO:0003713//transcription coactivator activity;GO:0046966//thyroid hormone receptor binding;GO:0004872//receptor activity;GO:0003712//transcription cofactor activity;GO:0003824//catalytic activity;GO:0030375//thyroid hormone receptor coactivator activity","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0030521//androgen receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated","K15159//mediator of RNA polymerase II transcription subunit 16","NP_005472.2//mediator of RNA polymerase II transcription subunit 16 [Homo sapiens]","2//1"]
[728888,3497,5.56,7.99,0.523110620204469,{"v":3.87959319918817e-05,"d":"3.88E-05"},"*",{"v":8.37656e-06,"d":"8.38E-06"},"NPIPB11","GO:0005654//nucleoplasm;GO:0016021//integral component of membrane","NA","NA","K09187//histone-lysine N-methyltransferase MLL2 [EC:2.1.1.43]","NP_001297066.1//nuclear pore complex-interacting protein family member B11 [Homo sapiens]","1//3"]
[51651,1096,47.47,68.17,0.522120933275828,{"v":2.19568791292002e-08,"d":"2.20E-08"},"*",{"v":2.9044E-9,"d":"2.90E-09"},"PTRH2","GO:0016020//membrane;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005739//mitochondrion","GO:0004045//aminoacyl-tRNA hydrolase activity","GO:2000811//negative regulation of anoikis;GO:2000210//positive regulation of anoikis;GO:0010629//negative regulation of gene expression;GO:0006915//apoptotic process","K04794//peptidyl-tRNA hydrolase, PTH2 family [EC:3.1.1.29]","XP_008968798.1//PREDICTED: peptidyl-tRNA hydrolase 2, mitochondrial isoform X1 [Pan paniscus];NP_001015509.1//peptidyl-tRNA hydrolase 2, mitochondrial isoform a [Homo sapiens]","4;2//1"]
[84557,994,8.47,12.15,0.520522439160945,0.0102506369025271,"*",0.00355506,"MAP1LC3A","GO:0044754//autolysosome;GO:0005874//microtubule;GO:0005770//late endosome;GO:0031090//organelle membrane;GO:0005829//cytosol;GO:0005776//autophagosome;GO:0000421//autophagosome membrane","GO:0008429//phosphatidylethanolamine binding;GO:0031625//ubiquitin protein ligase binding;GO:0005543//phospholipid binding","GO:0034198//cellular response to amino acid starvation;GO:0009267//cellular response to starvation;GO:0043278//response to morphine;GO:0071280//cellular response to copper ion;GO:0000422//autophagy of mitochondrion;GO:0097352//autophagosome maturation;GO:0010288//response to lead ion;GO:0006995//cellular response to nitrogen starvation;GO:0006914//autophagy;GO:0010040//response to iron(II) ion;GO:0000045//autophagosome assembly;GO:0016236//macroautophagy;GO:0070301//cellular response to hydrogen peroxide","K10435//microtubule-associated protein 1 light chain","XP_011527385.1//PREDICTED: microtubule-associated proteins 1A/1B light chain 3A isoform X1 [Homo sapiens];NP_852610.1//microtubule-associated proteins 1A/1B light chain 3A isoform b [Homo sapiens]","3//A2MP1;2//1"]
[4832,1038,15.84,22.72,0.520390499425072,0.000286809565794066,"*",{"v":7.20166e-05,"d":"7.20E-05"},"NME3","GO:0070062//extracellular exosome;GO:0005739//mitochondrion","GO:0005524//ATP binding;GO:0004550//nucleoside diphosphate kinase activity","GO:0006228//UTP biosynthetic process;GO:0006241//CTP biosynthetic process;GO:0006183//GTP biosynthetic process","K00940//nucleoside-diphosphate kinase [EC:2.7.4.6]","XP_017713829.1//PREDICTED: nucleoside diphosphate kinase 3 isoform X1 [Rhinopithecus bieti]","2//1"]
[3489,980,53.25,76.37,0.520224498380649,{"v":1.80086545893459e-11,"d":"1.80E-11"},"*",{"v":1.671894e-12,"d":"1.67E-12"},"IGFBP6","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0042568//insulin-like growth factor binary complex;GO:0005794//Golgi apparatus;GO:0005576//extracellular region","GO:0005520//insulin-like growth factor binding;GO:0031994//insulin-like growth factor I binding;GO:0005102//receptor binding;GO:0031995//insulin-like growth factor II binding","GO:0001558//regulation of cell growth;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0044267//cellular protein metabolic process;GO:0007165//signal transduction;GO:0043567//regulation of insulin-like growth factor receptor signaling pathway;GO:0008285//negative regulation of cell proliferation","K10138//insulin-like growth factor-binding protein 3;K00637//sterol O-acyltransferase [EC:2.3.1.26]","NP_002169.1//insulin-like growth factor-binding protein 6 precursor [Homo sapiens]","2//1"]
[59,1805,3.71,5.32,0.520007058880386,0.0327229366113373,"*",0.0130818,"ACTA2","NA","NA","NA","K12313//actin, aortic smooth muscle","XP_004858412.2//actin, aortic smooth muscle [Heterocephalus glaber];XP_019844282.1//PREDICTED: actin, aortic smooth muscle [Bos indicus];KFO23287.1//Actin, aortic smooth muscle [Fukomys damarensis]","1//3;3//A2MP1;2//1"]
[3660,2302,8.9,12.76,0.519751087911109,{"v":3.50572750731422e-05,"d":"3.51E-05"},"*",{"v":7.5013e-06,"d":"7.50E-06"},"IRF2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005925//focal adhesion;GO:0005829//cytosol","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0060337//type I interferon signaling pathway;GO:0008283//cell proliferation;GO:0007596//blood coagulation;GO:0006355//regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0051607//defense response to virus;GO:0006351//transcription, DNA-templated","K10153//interferon regulatory factor 2","XP_007998574.1//PREDICTED: interferon regulatory factor 2 isoform X1 [Chlorocebus sabaeus]","3//A2MP1"]
[653145,2049,8.03,11.51,0.519415940614916,0.00370909279442231,"*",0.001165622,"ANXA8","NA","GO:0005544//calcium-dependent phospholipid binding;GO:0005509//calcium ion binding","NA","K17096//annexin A8","NP_001258632.1//annexin A8 isoform 3 [Homo sapiens];BAG60903.1//unnamed protein product [Homo sapiens];NP_001258631.1//annexin A8 isoform 1 [Homo sapiens]","1//3;2//1"]
[51333,1460,5.22,7.48,0.518988463317752,0.0174484397422855,"*",6.4424E-3,"ZNF771","NA","GO:0003676//nucleic acid binding","NA","K09228//KRAB domain-containing zinc finger protein","XP_006148225.1//PREDICTED: zinc finger protein 771 [Tupaia chinensis];ELW66355.1//Zinc finger protein 629 [Tupaia chinensis]","1//3;3//A2MP1"]
[9020,4499,28.35,40.61,0.518486292094734,{"v":1.05658505636743E-27,"d":"1.06E-27"},"*",{"v":3.1683e-29,"d":"3.17E-29"},"MAP3K14","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005829//cytosol;GO:0001650//fibrillar center;GO:0005737//cytoplasm","GO:0004709//MAP kinase kinase kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004704//NF-kappaB-inducing kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0016301//kinase activity","GO:0023014//signal transduction by protein phosphorylation;GO:0038061//NIK/NF-kappaB signaling;GO:0007346//regulation of mitotic cell cycle;GO:0071260//cellular response to mechanical stimulus;GO:0051607//defense response to virus;GO:0032147//activation of protein kinase activity;GO:0031295//T cell costimulation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0006955//immune response;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0031098//stress-activated protein kinase signaling cascade;GO:0042981//regulation of apoptotic process","K04466//mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]","NP_003945.2//mitogen-activated protein kinase kinase kinase 14 [Homo sapiens]",4]
[4359,1970,0.37,0.53,0.518467088934249,0.557656471445929,"*",0.402236,"MPZ","GO:0016323//basolateral plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005791//rough endoplasmic reticulum;GO:0043209//myelin sheath;GO:0005764//lysosome;GO:0005886//plasma membrane","GO:0005198//structural molecule activity","GO:0042552//myelination;GO:0098742//cell-cell adhesion via plasma-membrane adhesion molecules;GO:0007268//chemical synaptic transmission;GO:0098743//cell aggregation;GO:0043066//negative regulation of apoptotic process","K06770//myelin protein zero","NP_001302420.1//myelin protein P0 isoform L-MPZ precursor [Homo sapiens]","1//3;7"]
[387509,4098,0.81,1.16,0.518130992242947,0.146654080178616,"*",0.0740156,"GPR153","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004930//G-protein coupled receptor activity","NA","K08437//G protein-coupled receptor 153","NP_997253.2//probable G-protein coupled receptor 153 [Homo sapiens]","3//A2MP1"]
[666,2663,14.44,20.67,0.517467646538277,{"v":7.42610298642534e-09,"d":"7.43E-09"},"*",{"v":9.2466e-10,"d":"9.25E-10"},"BOK","GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0005741//mitochondrial outer membrane;GO:0033106//cis-Golgi network membrane;GO:0005737//cytoplasm;GO:0032588//trans-Golgi network membrane;GO:0055038//recycling endosome membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005640//nuclear outer membrane;GO:0005634//nucleus;GO:0031901//early endosome membrane;GO:0005794//Golgi apparatus;GO:0005743//mitochondrial inner membrane;GO:0005789//endoplasmic reticulum membrane;GO:0031966//mitochondrial membrane","GO:0031625//ubiquitin protein ligase binding;GO:0046982//protein heterodimerization activity;GO:0051400//BH domain binding;GO:0005102//receptor binding;GO:0042803//protein homodimerization activity","GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:1901382//regulation of chorionic trophoblast cell proliferation;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:1904708//regulation of granulosa cell apoptotic process;GO:1903899//positive regulation of PERK-mediated unfolded protein response;GO:0051402//neuron apoptotic process;GO:0007420//brain development;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0008584//male gonad development;GO:0043065//positive regulation of apoptotic process;GO:0008283//cell proliferation;GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0010506//regulation of autophagy;GO:1900119//positive regulation of execution phase of apoptosis;GO:0001836//release of cytochrome c from mitochondria;GO:0051259//protein oligomerization;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:1902237//positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway;GO:0043524//negative regulation of neuron apoptotic process;GO:0048709//oligodendrocyte differentiation;GO:0060546//negative regulation of necroptotic process;GO:1901029//negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway;GO:0006915//apoptotic process;GO:1901030//positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway;GO:0051902//negative regulation of mitochondrial depolarization;GO:0008635//activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0042981//regulation of apoptotic process","K02561//Bcl-2-related ovarian killer protein","NP_115904.1//bcl-2-related ovarian killer protein [Homo sapiens]",4]
[79798,3997,5.69,8.14,0.516600141959666,{"v":2.26641390215589e-07,"d":"2.27E-07"},"*",{"v":3.42218e-08,"d":"3.42E-08"},"ARMC5","GO:0005654//nucleoplasm;GO:0005925//focal adhesion;GO:0005829//cytosol;GO:0005737//cytoplasm","NA","NA","K06237//collagen, type IV, alpha;K16628//collagen, type VII, alpha;K13172//serine/arginine repetitive matrix protein 2","NP_001288749.1//armadillo repeat-containing protein 5 isoform d [Homo sapiens];NP_001275696.1//armadillo repeat-containing protein 5 isoform c [Homo sapiens];EAW52133.1//armadillo repeat containing 5, isoform CRA_c, partial [Homo sapiens]","1//3;2//1"]
[6748,741,128.22,183.42,0.516529644227159,{"v":6.95524491456077e-19,"d":"6.96E-19"},"*",{"v":3.61826e-20,"d":"3.62E-20"},"SSR4","GO:0070062//extracellular exosome;GO:0005784//Sec61 translocon complex;GO:0016021//integral component of membrane","NA","NA","K04571//translocon-associated protein subunit delta","NP_001191456.1//translocon-associated protein subunit delta isoform 3 precursor [Homo sapiens];NP_001191455.1//translocon-associated protein subunit delta isoform 1 precursor [Homo sapiens]","1//3;2//1"]
[84954,1653,4.16,5.95,0.516306140054214,0.0337411861985019,"*",0.01353534,"MPND","NA","GO:0046872//metal ion binding;GO:0008237//metallopeptidase activity","NA","K19475//WAS/WASL-interacting protein","NP_001153318.1//MPN domain-containing protein isoform 2 [Homo sapiens];NP_116257.2//MPN domain-containing protein isoform 1 [Homo sapiens];XP_007993024.1//PREDICTED: MPN domain-containing protein [Chlorocebus sabaeus]","1//3;2//1;5"]
[571,5761,1.21,1.73,0.51576499036213,0.02353659351316,"*",0.00901298,"BACH1","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0031463//Cul3-RING ubiquitin ligase complex","GO:0020037//heme binding;GO:0001205//transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0001206//transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0006281//DNA repair;GO:0006355//regulation of transcription, DNA-templated;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0016567//protein ubiquitination;GO:0000117//regulation of transcription involved in G2/M transition of mitotic cell cycle;GO:0006366//transcription from RNA polymerase II promoter","K09042//transcription regulator BACH","NP_001177.1//transcription regulator protein BACH1 [Homo sapiens]","3//A2MP1;2//1"]
[977,1520,221.27,316.33,0.515622521766505,{"v":4.12053133333333e-69,"d":"4.12E-69"},"*",{"v":3.7919e-71,"d":"3.79E-71"},"CD151","GO:0016020//membrane;GO:0005887//integral component of plasma membrane;GO:0005925//focal adhesion;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005604//basement membrane","GO:0005178//integrin binding","GO:0016477//cell migration;GO:0007155//cell adhesion;GO:0042098//T cell proliferation;GO:0007166//cell surface receptor signaling pathway;GO:0031581//hemidesmosome assembly","K06537//CD151 antigen","NP_004348.2//CD151 antigen [Homo sapiens];XP_007993783.1//PREDICTED: CD151 antigen isoform X1 [Chlorocebus sabaeus]","4;1//3;3//A2MP1"]
[9050,3054,2.26,3.23,0.515211392278737,0.0260250266042003,"*",0.01008482,"PSTPIP2","GO:0016020//membrane;GO:0005856//cytoskeleton;GO:0005829//cytosol","GO:0003779//actin binding","GO:0016477//cell migration;GO:0007010//cytoskeleton organization","K20124//proline-serine-threonine phosphatase interacting protein 2","NP_077748.3//proline-serine-threonine phosphatase-interacting protein 2 [Homo sapiens]","3//A2MP1"]
[118932,3993,0.35,0.5,0.514573172829758,0.421977295844453,"*",0.277162,"ANKRD22","GO:0016021//integral component of membrane","NA","NA","K19406//lipase-like abhydrolase domain-containing protein 3 [EC:3.1.1.-]","NP_653191.2//ankyrin repeat domain-containing protein 22 [Homo sapiens]","2//1"]
[23263,6424,0.07,0.1,0.514573172829758,0.71867546658729,"*",0.60458,"MCF2L","GO:0012505//endomembrane system;GO:0005615//extracellular space;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0035091//phosphatidylinositol binding","GO:0043065//positive regulation of apoptotic process;GO:0035025//positive regulation of Rho protein signal transduction;GO:0035023//regulation of Rho protein signal transduction;GO:0035556//intracellular signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction","K20685//guanine nucleotide exchange factor MCF2","NP_001106203.2//guanine nucleotide exchange factor DBS isoform a [Homo sapiens];NP_079255.4//guanine nucleotide exchange factor DBS isoform b precursor [Homo sapiens];NP_001307744.1//guanine nucleotide exchange factor DBS isoform c precursor [Homo sapiens];NP_001307745.1//guanine nucleotide exchange factor DBS isoform d [Homo sapiens];NP_001307746.1//guanine nucleotide exchange factor DBS isoform e precursor [Homo sapiens]","4;1//3;2//1"]
[100505767,1242,0.14,0.2,0.514573172829758,0.781418860241136,"*",0.685686,"SPDYE18","NA","NA","NA","K08694//speedy","NP_001338277.1//speedy/RINGO cell cycle regulator family member E18 [Homo sapiens]","1//3"]
[376132,2620,0.07,0.1,0.514573172829758,0.78136311627907,"*",0.685686,"LRRC10","GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0030017//sarcomere","GO:0003779//actin binding;GO:0051393//alpha-actinin binding","GO:0055013//cardiac muscle cell development","K17277//epidermal growth factor receptor kinase substrate 8;K12796//erbb2-interacting protein","NP_963844.2//leucine-rich repeat-containing protein 10 [Homo sapiens]","3//A2MP1"]
[440503,2445,0.35,0.5,0.514573172829758,0.475893794344473,"*",0.324492,"PLIN5","GO:0005811//lipid droplet;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005737//cytoplasm","GO:0035473//lipase binding;GO:0042802//identical protein binding","GO:0060193//positive regulation of lipase activity;GO:0060192//negative regulation of lipase activity;GO:0031999//negative regulation of fatty acid beta-oxidation;GO:0010867//positive regulation of triglyceride biosynthetic process;GO:0032000//positive regulation of fatty acid beta-oxidation;GO:0010890//positive regulation of sequestering of triglyceride;GO:0051646//mitochondrion localization;GO:0010897//negative regulation of triglyceride catabolic process;GO:0035359//negative regulation of peroxisome proliferator activated receptor signaling pathway;GO:0034389//lipid particle organization;GO:0010884//positive regulation of lipid storage;GO:0019915//lipid storage;GO:2000378//negative regulation of reactive oxygen species metabolic process","K20255//perilipin-5","NP_001013728.2//perilipin-5 [Homo sapiens]","2//1"]
[40,2747,0.21,0.3,0.514573172829758,0.557559689691079,"*",0.402236,"ASIC2","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0043197//dendritic spine;GO:0005886//plasma membrane;GO:0043025//neuronal cell body","GO:0022839//ion gated channel activity;GO:0044736//acid-sensing ion channel activity;GO:0015280//ligand-gated sodium channel activity","GO:0010468//regulation of gene expression;GO:0019229//regulation of vasoconstriction;GO:0035418//protein localization to synapse;GO:0034220//ion transmembrane transport;GO:0051965//positive regulation of synapse assembly;GO:0030193//regulation of blood coagulation;GO:0007602//phototransduction;GO:0003026//regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback;GO:0042391//regulation of membrane potential;GO:0034765//regulation of ion transmembrane transport;GO:0043066//negative regulation of apoptotic process;GO:0007417//central nervous system development;GO:0010447//response to acidic pH;GO:0007605//sensory perception of sound;GO:0007268//chemical synaptic transmission;GO:0007422//peripheral nervous system development;GO:0015672//monovalent inorganic cation transport;GO:0050974//detection of mechanical stimulus involved in sensory perception;GO:0050915//sensory perception of sour taste","K04828//acid-sensing ion channel 2","NP_899233.1//acid-sensing ion channel 2 isoform MDEG2 [Homo sapiens];NP_001085.2//acid-sensing ion channel 2 isoform MDEG1 [Homo sapiens]","1//3;4"]
[7576,4608,0.07,0.1,0.514573172829758,0.830497708474576,"*",0.751524,"ZNF28","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_016789787.1//PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 28 [Pan troglodytes]","3//A2MP1"]
[84163,947,5.91,8.44,0.514084868529653,0.0671676789975794,"*",0.0295304,"GTF2IRD2","GO:0005654//nucleoplasm;GO:0005737//cytoplasm","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0003677//DNA binding","GO:0007275//multicellular organism development;GO:0006351//transcription, DNA-templated","K03121//transcription initiation factor TFII-I","NP_001268376.1//general transcription factor II-I repeat domain-containing protein 2A isoform 2 [Homo sapiens];NP_775808.3//general transcription factor II-I repeat domain-containing protein 2A isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[56033,1498,4.54,6.48,0.51330151559371,0.0287597740819907,"*",0.01128678,"BARX1","GO:0005634//nucleus","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0009952//anterior/posterior pattern specification;GO:0048513//animal organ development;GO:0006355//regulation of transcription, DNA-templated;GO:0009888//tissue development;GO:0030178//negative regulation of Wnt signaling pathway;GO:0007267//cell-cell signaling;GO:0055123//digestive system development;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0048536//spleen development;GO:0030855//epithelial cell differentiation","K09361//BarH-like homeobox","XP_011769558.1//PREDICTED: homeobox protein BarH-like 1 [Macaca nemestrina]","3//A2MP1"]
[7089,2708,1.1,1.57,0.513261035366967,0.21288195951417,"*",0.11521,"TLE2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005615//extracellular space;GO:0005925//focal adhesion;GO:0016604//nuclear body","GO:0003714//transcription corepressor activity","GO:0045892//negative regulation of transcription, DNA-templated;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:1904837//beta-catenin-TCF complex assembly;GO:0009887//animal organ morphogenesis;GO:0007165//signal transduction;GO:0006355//regulation of transcription, DNA-templated;GO:0016055//Wnt signaling pathway;GO:0006351//transcription, DNA-templated","K04497//groucho","NP_003251.2//transducin-like enhancer protein 2 isoform 1 [Homo sapiens];NP_001287775.1//transducin-like enhancer protein 2 isoform 4 [Homo sapiens];NP_001138233.1//transducin-like enhancer protein 2 isoform 2 [Homo sapiens];XP_010365609.1//PREDICTED: transducin-like enhancer protein 2 [Rhinopithecus roxellana]","4;1//3"]
[163033,2173,30.53,43.54,0.512113817981427,{"v":2.80640669949066e-14,"d":"2.81E-14"},"*",{"v":2.06958E-15,"d":"2.07E-15"},"ZNF579","GO:0005634//nucleus","GO:0003723//RNA binding;GO:0046872//metal ion binding;GO:0003677//DNA binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","NP_689813.2//zinc finger protein 579 [Homo sapiens]","2//1"]
[51131,1726,5.12,7.3,0.51175265376738,0.0105766781082539,"*",0.00368204,"PHF11","GO:0005654//nucleoplasm;GO:0031965//nuclear membrane","GO:0046872//metal ion binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K18494//histone-lysine N-methyltransferase SETDB2 [EC:2.1.1.43]","NP_001035533.1//PHD finger protein 11 isoform a [Homo sapiens]","2//1"]
[150383,1502,9.49,13.53,0.511681846955428,0.000929168724324324,"*",0.000258264,"CDPF1","NA","NA","NA","K22073//transferase CAF17, mitochondrial [EC:2.1.-.-]","XP_016794888.1//PREDICTED: cysteine-rich DPF motif domain-containing protein 1 isoform X4 [Pan troglodytes]",4]
[1428,1559,0.47,0.67,0.511500338780135,0.557753286805555,"*",0.402236,"CRYM","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005782//peroxisomal matrix;GO:0005739//mitochondrion;GO:0005737//cytoplasm","GO:0050661//NADP binding;GO:0047127//thiomorpholine-carboxylate dehydrogenase activity;GO:0003714//transcription corepressor activity;GO:0070324//thyroid hormone binding;GO:0042803//protein homodimerization activity;GO:0016639//oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0070327//thyroid hormone transport;GO:0007605//sensory perception of sound;GO:0006554//lysine catabolic process;GO:0042403//thyroid hormone metabolic process","K18258//thiomorpholine-carboxylate dehydrogenase [EC:1.5.1.25]","NP_001879.1//ketimine reductase mu-crystallin [Homo sapiens]",4]
[200844,2366,1.81,2.58,0.511381368340049,0.901883867952323,"*",0.843166,"C3orf67","NA","NA","NA","NA","XP_011531762.1//PREDICTED: uncharacterized protein C3orf67 isoform X8 [Homo sapiens];NP_001338462.1//uncharacterized protein C3orf67 isoform 5 [Homo sapiens];XP_011531761.1//PREDICTED: uncharacterized protein C3orf67 isoform X7 [Homo sapiens];NP_001338459.1//uncharacterized protein C3orf67 isoform 1 [Homo sapiens];NP_001338463.1//uncharacterized protein C3orf67 isoform 6 [Homo sapiens]","1//3;3//A2MP1"]
[3556,3972,1.2,1.71,0.510961919277379,0.165888439126214,"*",0.0855716,"IL1RAP","GO:0016020//membrane;GO:0005615//extracellular space;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:1990782//protein tyrosine kinase binding;GO:0004871//signal transducer activity;GO:0002114//interleukin-33 receptor activity;GO:0004908//interleukin-1 receptor activity","GO:1900006//positive regulation of dendrite development;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051965//positive regulation of synapse assembly;GO:0006954//inflammatory response;GO:0042094//interleukin-2 biosynthetic process;GO:0072602//interleukin-4 secretion;GO:0032754//positive regulation of interleukin-5 production;GO:0006955//immune response;GO:0032736//positive regulation of interleukin-13 production;GO:0006461//protein complex assembly;GO:0045087//innate immune response;GO:2000778//positive regulation of interleukin-6 secretion","K04723//interleukin 1 receptor accessory protein","NP_001161403.1//interleukin-1 receptor accessory protein isoform 3 precursor [Homo sapiens];NP_002173.1//interleukin-1 receptor accessory protein isoform 1 precursor [Homo sapiens];NP_608273.1//interleukin-1 receptor accessory protein isoform 2 precursor [Homo sapiens]","1//3;3//A2MP1"]
[8477,4522,0.33,0.47,0.510194732319184,0.370721795704346,"*",0.230152,"GPR65","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004930//G-protein coupled receptor activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway;GO:0090630//activation of GTPase activity;GO:0031532//actin cytoskeleton reorganization;GO:0006915//apoptotic process;GO:0051496//positive regulation of stress fiber assembly;GO:0035025//positive regulation of Rho protein signal transduction;GO:0010447//response to acidic pH;GO:0007275//multicellular organism development;GO:0006955//immune response;GO:0030819//positive regulation of cAMP biosynthetic process","K08416//G protein-coupled receptor 65","XP_011804845.1//PREDICTED: psychosine receptor [Colobus angolensis palliatus]","3//A2MP1"]
[23580,3121,40.74,57.99,0.509358157966504,{"v":1.76599147529412e-26,"d":"1.77E-26"},"*",{"v":5.63826e-28,"d":"5.64E-28"},"CDC42EP4","GO:0012505//endomembrane system;GO:0005913//cell-cell adherens junction;GO:0015630//microtubule cytoskeleton;GO:0015629//actin cytoskeleton;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0017049//GTP-Rho binding;GO:0005096//GTPase activator activity","GO:0007266//Rho protein signal transduction;GO:0031274//positive regulation of pseudopodium assembly;GO:0030838//positive regulation of actin filament polymerization;GO:0008360//regulation of cell shape","K14404//cleavage and polyadenylation specificity factor subunit 4","NP_036253.2//cdc42 effector protein 4 [Homo sapiens]",4]
[56938,7327,4.11,5.85,0.509298230789084,{"v":3.8823096872494e-07,"d":"3.88E-07"},"*",{"v":6.0614e-08,"d":"6.06E-08"},"ARNTL2","GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005667//transcription factor complex;GO:0005737//cytoplasm","GO:0000982//transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0070888//E-box binding;GO:0003700//DNA binding transcription factor activity;GO:0046983//protein dimerization activity","GO:0007623//circadian rhythm;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006355//regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0042753//positive regulation of circadian rhythm;GO:0009649//entrainment of circadian clock;GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated","K09099//aryl hydrocarbon receptor nuclear translocator-like protein 2","XP_003906194.2//aryl hydrocarbon receptor nuclear translocator-like protein 2 isoform X2 [Papio anubis];XP_016779241.1//PREDICTED: aryl hydrocarbon receptor nuclear translocator-like protein 2 isoform X13 [Pan troglodytes];XP_003906190.2//aryl hydrocarbon receptor nuclear translocator-like protein 2 isoform X3 [Papio anubis]","4;1//3"]
[84062,1372,7.87,11.2,0.50906319143748,0.0169414233333333,"*",0.00622338,"DTNBP1","GO:0010008//endosome membrane;GO:0030054//cell junction;GO:0005737//cytoplasm;GO:0030496//midbody;GO:0030426//growth cone;GO:0030672//synaptic vesicle membrane;GO:0016528//sarcoplasm;GO:0005829//cytosol;GO:0043197//dendritic spine;GO:0045211//postsynaptic membrane;GO:0030424//axon;GO:1904115//axon cytoplasm;GO:0031083//BLOC-1 complex;GO:0005634//nucleus;GO:0015630//microtubule cytoskeleton;GO:0033162//melanosome membrane;GO:0014069//postsynaptic density;GO:0043005//neuron projection;GO:0042383//sarcolemma;GO:0005789//endoplasmic reticulum membrane","NA","GO:0007596//blood coagulation;GO:0014059//regulation of dopamine secretion;GO:0001956//positive regulation of neurotransmitter secretion;GO:0048812//neuron projection morphogenesis;GO:0048490//anterograde synaptic vesicle transport;GO:0043506//regulation of JUN kinase activity;GO:0032091//negative regulation of protein binding;GO:0031175//neuron projection development;GO:0031532//actin cytoskeleton reorganization;GO:0060159//regulation of dopamine receptor signaling pathway;GO:0071901//negative regulation of protein serine/threonine kinase activity;GO:0060155//platelet dense granule organization;GO:0010628//positive regulation of gene expression;GO:0048813//dendrite morphogenesis;GO:0008089//anterograde axonal transport;GO:0032438//melanosome organization","K20189//dysbindin","NP_001258598.1//dysbindin isoform e [Homo sapiens];NP_001258597.1//dysbindin isoform d [Homo sapiens];NP_115498.2//dysbindin isoform a [Homo sapiens];NP_898861.1//dysbindin isoform b [Homo sapiens]","4;1//3;2//1"]
[8379,1809,4.09,5.82,0.508918309966535,0.0195385160655738,"*",0.00731196,"MAD1L1","GO:0072686//mitotic spindle;GO:0005643//nuclear pore;GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005813//centrosome;GO:0097431//mitotic spindle pole;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0005819//spindle;GO:0000777//condensed chromosome kinetochore;GO:0000776//kinetochore","GO:0042802//identical protein binding;GO:0043515//kinetochore binding","GO:0090235//regulation of metaphase plate congression;GO:0007093//mitotic cell cycle checkpoint;GO:0042130//negative regulation of T cell proliferation;GO:0051315//attachment of mitotic spindle microtubules to kinetochore;GO:0007062//sister chromatid cohesion;GO:0051301//cell division;GO:0048538//thymus development;GO:0007094//mitotic spindle assembly checkpoint","K06638//mitotic spindle assembly checkpoint protein MAD1","NP_003541.2//mitotic spindle assembly checkpoint protein MAD1 isoform a [Homo sapiens];XP_017749939.1//PREDICTED: mitotic spindle assembly checkpoint protein MAD1 isoform X4 [Rhinopithecus bieti];NP_001291453.1//mitotic spindle assembly checkpoint protein MAD1 isoform b precursor [Homo sapiens]","1//3;2//1"]
[7376,1962,50.65,72.07,0.508836576319529,{"v":7.46322901199041e-19,"d":"7.46E-19"},"*",{"v":3.89654e-20,"d":"3.90E-20"},"NR1H2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm","GO:0003707//steroid hormone receptor activity;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0051117//ATPase binding;GO:0004879//nuclear receptor activity;GO:0034191//apolipoprotein A-I receptor binding;GO:0046965//retinoid X receptor binding;GO:0001133//RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding;GO:0043565//sequence-specific DNA binding;GO:0008270//zinc ion binding;GO:0003700//DNA binding transcription factor activity","GO:0010875//positive regulation of cholesterol efflux;GO:0010867//positive regulation of triglyceride biosynthetic process;GO:0045861//negative regulation of proteolysis;GO:0032270//positive regulation of cellular protein metabolic process;GO:0032369//negative regulation of lipid transport;GO:0010884//positive regulation of lipid storage;GO:0048550//negative regulation of pinocytosis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0044255//cellular lipid metabolic process;GO:0042632//cholesterol homeostasis;GO:0090108//positive regulation of high-density lipoprotein particle assembly;GO:0090187//positive regulation of pancreatic juice secretion;GO:0045892//negative regulation of transcription, DNA-templated;GO:0090340//positive regulation of secretion of lysosomal enzymes;GO:0048384//retinoic acid receptor signaling pathway;GO:0060336//negative regulation of interferon-gamma-mediated signaling pathway;GO:0006351//transcription, DNA-templated;GO:0032376//positive regulation of cholesterol transport;GO:0010887//negative regulation of cholesterol storage;GO:0010745//negative regulation of macrophage derived foam cell differentiation;GO:0045723//positive regulation of fatty acid biosynthetic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0051006//positive regulation of lipoprotein lipase activity;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:2000188//regulation of cholesterol homeostasis","K08535//liver X receptor beta","XP_012365439.1//PREDICTED: oxysterols receptor LXR-beta isoform X1 [Nomascus leucogenys];NP_001243576.1//oxysterols receptor LXR-beta isoform 2 [Homo sapiens]","1//3;5"]
[7389,1408,18.79,26.73,0.508494770823023,{"v":4.14236106091718e-06,"d":"4.14E-06"},"*",{"v":7.5773e-07,"d":"7.58E-07"},"UROD","GO:0005654//nucleoplasm;GO:0005829//cytosol","GO:0004853//uroporphyrinogen decarboxylase activity","GO:0006782//protoporphyrinogen IX biosynthetic process;GO:0006783//heme biosynthetic process","K01599//uroporphyrinogen decarboxylase [EC:4.1.1.37]","NP_000365.3//uroporphyrinogen decarboxylase [Homo sapiens]",4]
[150290,2581,2.25,3.2,0.508146903670325,0.172833366883586,"*",0.0897816,"DUSP18","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005743//mitochondrial inner membrane;GO:0005737//cytoplasm","GO:0017017//MAP kinase tyrosine/serine/threonine phosphatase activity;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0016791//phosphatase activity","GO:0035970//peptidyl-threonine dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0016311//dephosphorylation","K14165//atypical dual specificity phosphatase [EC:3.1.3.16 3.1.3.48]","NP_001291725.1//dual specificity protein phosphatase 18 isoform b [Homo sapiens];NP_689724.3//dual specificity protein phosphatase 18 isoform a [Homo sapiens]","1//3;4"]
[79957,2124,5.69,8.09,0.507711050123396,0.00667553309159585,"*",0.00221278,"PAQR6","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0003707//steroid hormone receptor activity;GO:0005496//steroid binding","GO:0048545//response to steroid hormone","K17387//kinesin family member 23;K21125//mucin-5AC;K07297//adiponectin receptor","XP_008972790.1//PREDICTED: progestin and adipoQ receptor family member 6 isoform X12 [Pan paniscus];XP_004002657.2//PREDICTED: progestin and adipoQ receptor family member 6 isoform X1 [Ovis aries];XP_008972795.1//PREDICTED: progestin and adipoQ receptor family member 6 isoform X17 [Pan paniscus];NP_001259038.1//progestin and adipoQ receptor family member 6 isoform 7 [Homo sapiens];XP_017365484.1//PREDICTED: progestin and adipoQ receptor family member 6 isoform X3 [Cebus capucinus imitator];XP_017707931.1//PREDICTED: progestin and adipoQ receptor family member 6 isoform X1 [Rhinopithecus bieti];XP_008972791.1//PREDICTED: progestin and adipoQ receptor family member 6 isoform X13 [Pan paniscus];NP_001259035.1//progestin and adipoQ receptor family member 6 isoform 4 [Homo sapiens];XP_008972777.1//PREDICTED: progestin and adipoQ receptor family member 6 isoform X3 [Pan paniscus]","1//3;3//A2MP1;2//1"]
[4615,2660,18.66,26.53,0.507675689376937,{"v":3.30011706320142e-10,"d":"3.30E-10"},"*",{"v":3.49762e-11,"d":"3.50E-11"},"MYD88","GO:0010008//endosome membrane;GO:0005634//nucleus;GO:0043234//protein complex;GO:0005829//cytosol;GO:0014069//postsynaptic density;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0035325//Toll-like receptor binding;GO:0005121//Toll binding;GO:0070976//TIR domain binding;GO:0042802//identical protein binding;GO:0005123//death receptor binding;GO:0043621//protein self-association;GO:0005149//interleukin-1 receptor binding","GO:0046330//positive regulation of JNK cascade;GO:0060337//type I interferon signaling pathway;GO:0032481//positive regulation of type I interferon production;GO:0016064//immunoglobulin mediated immune response;GO:0071260//cellular response to mechanical stimulus;GO:0032740//positive regulation of interleukin-17 production;GO:0007166//cell surface receptor signaling pathway;GO:0032760//positive regulation of tumor necrosis factor production;GO:0070555//response to interleukin-1;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0002238//response to molecule of fungal origin;GO:0007165//signal transduction;GO:0050671//positive regulation of lymphocyte proliferation;GO:0043066//negative regulation of apoptotic process;GO:0010628//positive regulation of gene expression;GO:0006915//apoptotic process;GO:0009682//induced systemic resistance;GO:0044130//negative regulation of growth of symbiont in host;GO:0019221//cytokine-mediated signaling pathway;GO:1900017//positive regulation of cytokine production involved in inflammatory response;GO:0032494//response to peptidoglycan;GO:1902622//regulation of neutrophil migration;GO:0032755//positive regulation of interleukin-6 production;GO:0070935//3'-UTR-mediated mRNA stabilization;GO:0034162//toll-like receptor 9 signaling pathway;GO:0008063//Toll signaling pathway;GO:0050830//defense response to Gram-positive bacterium;GO:2000338//regulation of chemokine (C-X-C motif) ligand 1 production;GO:0032747//positive regulation of interleukin-23 production;GO:0090557//establishment of endothelial intestinal barrier;GO:0045351//type I interferon biosynthetic process;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0140052//cellular response to oxidised low-density lipoprotein particle stimulus;GO:0002224//toll-like receptor signaling pathway;GO:0006954//inflammatory response;GO:0007254//JNK cascade;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0050727//regulation of inflammatory response;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0045080//positive regulation of chemokine biosynthetic process;GO:2000341//regulation of chemokine (C-X-C motif) ligand 2 production;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0009615//response to virus","K04729//myeloid differentiation primary response protein MyD88","NP_002459.2//myeloid differentiation primary response protein MyD88 isoform 2 [Homo sapiens];ANK58157.1//myeloid differentiation primary response 88 [Homo sapiens];NP_001166039.1//myeloid differentiation primary response protein MyD88 isoform 3 [Homo sapiens];NP_001166038.1//myeloid differentiation primary response protein MyD88 isoform 1 [Homo sapiens];NP_001166040.1//myeloid differentiation primary response protein MyD88 isoform 4 [Homo sapiens]","4;1//3"]
[126119,877,52.36,74.44,0.507612958113911,{"v":2.08521610526316e-09,"d":"2.09E-09"},"*",{"v":2.43062E-10,"d":"2.43E-10"},"JOSD2","GO:0005829//cytosol","GO:0004843//thiol-dependent ubiquitin-specific protease activity;GO:0036459//thiol-dependent ubiquitinyl hydrolase activity","GO:0016579//protein deubiquitination","K15235//josephin [EC:3.4.19.12]","AAH51380.1//JOSD2 protein, partial [Homo sapiens];XP_008986709.1//PREDICTED: josephin-2 isoform X3 [Callithrix jacchus]","1//3;3//A2MP1"]
[91734,1359,2.15,3.05,0.504472582860788,0.20084188441528,"*",0.1072984,"IDI2","GO:0005829//cytosol;GO:0005777//peroxisome","GO:0046872//metal ion binding;GO:0016787//hydrolase activity;GO:0004452//isopentenyl-diphosphate delta-isomerase activity","GO:0008299//isoprenoid biosynthetic process;GO:0009240//isopentenyl diphosphate biosynthetic process;GO:0046490//isopentenyl diphosphate metabolic process;GO:0006695//cholesterol biosynthetic process;GO:0050992//dimethylallyl diphosphate biosynthetic process","K01823//isopentenyl-diphosphate Delta-isomerase [EC:5.3.3.2]","NP_150286.1//isopentenyl-diphosphate delta-isomerase 2 [Homo sapiens]","2//1"]
[662,1268,6.63,9.4,0.503651886452412,0.027273005984252,"*",0.01062476,"BNIP1","GO:0043231//intracellular membrane-bounded organelle;GO:0005783//endoplasmic reticulum;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0031201//SNARE complex;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005739//mitochondrion","GO:0005484//SNAP receptor activity","GO:0097194//execution phase of apoptosis;GO:0016320//endoplasmic reticulum membrane fusion;GO:0006914//autophagy;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0043066//negative regulation of apoptotic process;GO:0007029//endoplasmic reticulum organization;GO:0006915//apoptotic process","K08497//protein transport protein SEC20","NP_053581.2//vesicle transport protein SEC20 isoform BNIP1-a [Homo sapiens];XP_012620958.1//vesicle transport protein SEC20 isoform X1 [Microcebus murinus];NP_053582.2//vesicle transport protein SEC20 isoform BNIP1-b [Homo sapiens];NP_053583.2//vesicle transport protein SEC20 isoform BNIP1-c [Homo sapiens]","2//1"]
[966,7592,22.43,31.8,0.503597145085445,{"v":4.53057737802817E-35,"d":"4.53E-35"},"*",{"v":1.006858E-36,"d":"1.01E-36"},"CD59","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0043218//compact myelin;GO:0031362//anchored component of external side of plasma membrane;GO:0005925//focal adhesion;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0031982//vesicle;GO:0000139//Golgi membrane;GO:0009986//cell surface;GO:0030133//transport vesicle;GO:0035579//specific granule membrane;GO:0042383//sarcolemma;GO:0005789//endoplasmic reticulum membrane;GO:0070821//tertiary granule membrane;GO:0005886//plasma membrane;GO:0012507//ER to Golgi transport vesicle membrane","GO:0001848//complement binding","GO:0030449//regulation of complement activation;GO:0007596//blood coagulation;GO:0042102//positive regulation of T cell proliferation;GO:0048208//COPII vesicle coating;GO:0043066//negative regulation of apoptotic process;GO:0007166//cell surface receptor signaling pathway;GO:0001775//cell activation;GO:0001971//negative regulation of activation of membrane attack complex;GO:0043312//neutrophil degranulation;GO:0006888//ER to Golgi vesicle-mediated transport","K04008//CD59 antigen","XP_011820940.1//PREDICTED: CD59 glycoprotein isoform X2 [Mandrillus leucophaeus];NP_000602.1//CD59 glycoprotein preproprotein [Homo sapiens];XP_012359677.1//PREDICTED: CD59 glycoprotein isoform X1 [Nomascus leucogenys]","1//3;2//1;5"]
[205860,1641,26.82,38.02,0.503449294744078,{"v":2.63208108704883e-09,"d":"2.63E-09"},"*",{"v":3.10432E-10,"d":"3.10E-10"},"TRIML2","NA","GO:0016740//transferase activity","GO:0016567//protein ubiquitination;GO:0032526//response to retinoic acid","K12039//tripartite motif family-like protein 2","NP_001290348.1//probable E3 ubiquitin-protein ligase TRIML2 isoform 1 [Homo sapiens];NP_775824.2//probable E3 ubiquitin-protein ligase TRIML2 isoform 2 [Homo sapiens]","1//3;2//1"]
[26074,4120,0.12,0.17,0.502500340529183,0.811351076491622,"*",0.724446,"CFAP61","GO:0031514//motile cilium;GO:0005737//cytoplasm;GO:0005930//axoneme","NA","GO:0003341//cilium movement;GO:0044782//cilium organization","K06756//neuronal cell adhesion molecule;K12869//crooked neck","XP_010367420.1//PREDICTED: uncharacterized protein C20orf26 homolog isoform X2 [Rhinopithecus roxellana];NP_056400.3//cilia- and flagella-associated protein 61 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[51160,1092,40.96,58.01,0.502085903985904,{"v":8.88915577181208e-10,"d":"8.89E-10"},"*",{"v":9.9498e-11,"d":"9.95E-11"},"VPS28","GO:0043657//host cell;GO:0070062//extracellular exosome;GO:0010008//endosome membrane;GO:0031902//late endosome membrane;GO:0000813//ESCRT I complex;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005769//early endosome","GO:0043130//ubiquitin binding;GO:0032403//protein complex binding","GO:0031397//negative regulation of protein ubiquitination;GO:0016197//endosomal transport;GO:0043328//protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0019058//viral life cycle;GO:0039702//viral budding via host ESCRT complex;GO:0036258//multivesicular body assembly;GO:0045732//positive regulation of protein catabolic process;GO:0075733//intracellular transport of virus;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0016236//macroautophagy;GO:2000397//positive regulation of ubiquitin-dependent endocytosis","K12184//ESCRT-I complex subunit VPS28","XP_011831091.1//PREDICTED: vacuolar protein sorting-associated protein 28 homolog isoform X1 [Mandrillus leucophaeus];XP_012328725.1//vacuolar protein sorting-associated protein 28 homolog isoform X1 [Aotus nancymaae]","3//A2MP1;2//1"]
[23253,11321,1.97,2.79,0.502069492372812,{"v":3.07039828436299e-05,"d":"3.07E-05"},"*",{"v":6.50254e-06,"d":"6.50E-06"},"ANKRD12","GO:0005654//nucleoplasm;GO:0005829//cytosol","NA","NA","K21436//ankyrin repeat domain-containing protein 11/12","NP_056023.3//ankyrin repeat domain-containing protein 12 isoform 1 [Homo sapiens];NP_001077094.1//ankyrin repeat domain-containing protein 12 isoform 2 [Homo sapiens]","4;1//3;2//1"]
[342667,3202,2.79,3.95,0.501587531235278,0.0119426258414613,"*",4.21588E-3,"STAC2","GO:0005622//intracellular","GO:0046872//metal ion binding","GO:0035556//intracellular signal transduction","K01368//cathepsin S [EC:3.4.22.27];K17985//activating molecule in BECN1-regulated autophagy protein 1;K01064//wingless-type MMTV integration site family, member 9","XP_019494012.1//PREDICTED: SH3 and cysteine-rich domain-containing protein 2 isoform X1 [Hipposideros armiger];NP_945344.1//SH3 and cysteine-rich domain-containing protein 2 isoform 1 [Homo sapiens]","4;1//3"]
[23677,5193,19.58,27.72,0.501546492533519,{"v":8.5397838954608e-21,"d":"8.54E-21"},"*",{"v":3.88658e-22,"d":"3.89E-22"},"SH3BP4","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0030136//clathrin-coated vesicle;GO:0005905//clathrin-coated pit;GO:0005737//cytoplasm","GO:0042802//identical protein binding;GO:0017016//Ras GTPase binding;GO:0005092//GDP-dissociation inhibitor activity","GO:0032007//negative regulation of TOR signaling;GO:0030308//negative regulation of cell growth;GO:0061462//protein localization to lysosome;GO:0050790//regulation of catalytic activity;GO:0010508//positive regulation of autophagy;GO:0071230//cellular response to amino acid stimulus;GO:0006897//endocytosis;GO:0034260//negative regulation of GTPase activity;GO:0008285//negative regulation of cell proliferation","K20066//SH3 domain-binding protein 4","NP_055336.1//SH3 domain-binding protein 4 [Homo sapiens]","2//1"]
[116211,1032,6.19,8.76,0.500991460386909,0.027934749955157,"*",0.01091928,"TM4SF19","GO:0016021//integral component of membrane","NA","NA","K00681//gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13];K13624//ceruloplasmin [EC:1.16.3.1]","NP_001191827.1//transmembrane 4 L6 family member 19 isoform 3 [Homo sapiens];NP_612470.2//transmembrane 4 L6 family member 19 isoform 1 [Homo sapiens];NP_001191826.1//transmembrane 4 L6 family member 19 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[1051,2113,121.71,172.24,0.500972516239805,{"v":9.29220649636364e-51,"d":"9.29E-51"},"*",{"v":1.279758e-52,"d":"1.28E-52"},"CEBPB","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0036488//CHOP-C/EBP complex;GO:0000779//condensed chromosome, centromeric region;GO:0016363//nuclear matrix;GO:0000790//nuclear chromatin;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0035259//glucocorticoid receptor binding;GO:0003705//transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0019900//kinase binding;GO:0003700//DNA binding transcription factor activity;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0042826//histone deacetylase binding;GO:0042803//protein homodimerization activity;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0035035//histone acetyltransferase binding;GO:0008134//transcription factor binding","GO:0097421//liver regeneration;GO:0034976//response to endoplasmic reticulum stress;GO:0071222//cellular response to lipopolysaccharide;GO:0001892//embryonic placenta development;GO:0042130//negative regulation of T cell proliferation;GO:0071347//cellular response to interleukin-1;GO:0032753//positive regulation of interleukin-4 production;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045600//positive regulation of fat cell differentiation;GO:0043524//negative regulation of neuron apoptotic process;GO:0033598//mammary gland epithelial cell proliferation;GO:0001541//ovarian follicle development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0060644//mammary gland epithelial cell differentiation;GO:0002432//granuloma formation;GO:0050873//brown fat cell differentiation;GO:0060850//regulation of transcription involved in cell fate commitment;GO:0035711//T-helper 1 cell activation;GO:0006355//regulation of transcription, DNA-templated;GO:0032496//response to lipopolysaccharide;GO:0042742//defense response to bacterium;GO:0071407//cellular response to organic cyclic compound;GO:0045408//regulation of interleukin-6 biosynthetic process;GO:0030182//neuron differentiation;GO:0006953//acute-phase response;GO:0072574//hepatocyte proliferation;GO:0045669//positive regulation of osteoblast differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0006954//inflammatory response;GO:0071230//cellular response to amino acid stimulus;GO:1990440//positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress;GO:0007613//memory;GO:0045670//regulation of osteoclast differentiation;GO:0006955//immune response","K10048//CCAAT/enhancer binding protein (C/EBP), beta","NP_005185.2//CCAAT/enhancer-binding protein beta isoform a [Homo sapiens]","1//3;3//A2MP1"]
[55017,2960,22.51,31.85,0.500727315689507,{"v":7.86939583319706e-14,"d":"7.87E-14"},"*",{"v":6.02496E-15,"d":"6.02E-15"},"C14orf119","GO:0005829//cytosol;GO:0005739//mitochondrion","NA","NA","K04372//MAP kinase interacting serine/threonine kinase [EC:2.7.11.1];K12581//CCR4-NOT transcription complex subunit 7/8;K16506//protocadherin Fat 1/2/3","NP_060394.1//uncharacterized protein C14orf119 [Homo sapiens]","3//A2MP1"]
[1503,2716,48.06,68,0.500698097895198,{"v":3.7293239559633e-20,"d":"3.73E-20"},"*",{"v":1.781316e-21,"d":"1.78E-21"},"CTPS1","GO:0016020//membrane","GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0003883//CTP synthase activity","GO:0006541//glutamine metabolic process;GO:0042098//T cell proliferation;GO:0042100//B cell proliferation;GO:0044210//'de novo' CTP biosynthetic process","K01937//CTP synthase [EC:6.3.4.2]","XP_003432053.1//CTP synthase 1 [Canis lupus familiaris]","1//3;3//A2MP1"]
[440348,1389,3.23,4.57,0.500660000364145,0.0972546574576727,"*",0.0453092,"NPIPB15","GO:0005654//nucleoplasm;GO:0005576//extracellular region","NA","NA","NA","NP_001293023.1//nuclear pore complex-interacting protein family member B15 precursor [Homo sapiens]","1//3"]
[7791,2323,128.09,181.22,0.500584335740311,{"v":1.33735364151351E-58,"d":"1.34E-58"},"*",{"v":1.548832E-60,"d":"1.55E-60"},"ZYX","NA","NA","NA","K06273//zyxin","XP_016868076.1//PREDICTED: zyxin isoform X1 [Homo sapiens];EAW51849.1//zyxin, isoform CRA_b [Homo sapiens]","1//3;4"]
[4709,770,33.78,47.79,0.50053943944508,{"v":1.08535081719051E-5,"d":"1.09E-05"},"*",{"v":2.11852e-06,"d":"2.12E-06"},"NDUFB3","GO:0070062//extracellular exosome;GO:0005747//mitochondrial respiratory chain complex I;GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane","GO:0008137//NADH dehydrogenase (ubiquinone) activity","GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0022900//electron transport chain;GO:0006120//mitochondrial electron transport, NADH to ubiquinone","K03959//NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 3","NP_002482.1//NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 [Homo sapiens]","1//3;2//1"]
[192286,906,127.76,180.74,0.500479609953562,{"v":1.99817642446483E-22,"d":"2.00E-22"},"*",{"v":8.18084e-24,"d":"8.18E-24"},"HIGD2A","GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0070469//respiratory chain","NA","GO:0097250//mitochondrial respiratory chain supercomplex assembly;GO:0043066//negative regulation of apoptotic process;GO:0055114//oxidation-reduction process","NA","XP_003280545.1//PREDICTED: HIG1 domain family member 2A, mitochondrial [Nomascus leucogenys]","3//A2MP1"]
[112399,2722,3.19,4.51,0.499571009490512,0.0145650155486111,"*",0.00525194,"EGLN3","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;GO:0005506//iron ion binding;GO:0031545//peptidyl-proline 4-dioxygenase activity;GO:0031418//L-ascorbic acid binding;GO:0031543//peptidyl-proline dioxygenase activity","GO:0042127//regulation of cell proliferation;GO:0018401//peptidyl-proline hydroxylation to 4-hydroxy-L-proline;GO:0001666//response to hypoxia;GO:0006915//apoptotic process;GO:0043523//regulation of neuron apoptotic process;GO:1990830//cellular response to leukemia inhibitory factor;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0018126//protein hydroxylation","K09592//hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]","XP_021035020.1//egl nine homolog 3 isoform X1 [Mus caroli];NP_001295032.1//egl nine homolog 3 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[389610,4980,0.87,1.23,0.499571009490512,0.091206820113852,"*",0.0421262,"XKR5","GO:0016021//integral component of membrane","NA","NA","K11447//histone demethylase [EC:1.14.11.-];K15144//mediator of RNA polymerase II transcription subunit 1;K17599//transmembrane protein 132","NP_997294.3//XK-related protein 5 isoform a [Homo sapiens];Q6UX68.1//RecName: Full=XK-related protein 5","1//3;4"]
[90480,772,43.98,62.17,0.499370974682477,{"v":4.0977910512e-07,"d":"4.10E-07"},"*",{"v":6.41322e-08,"d":"6.41E-08"},"GADD45GIP1","GO:0005759//mitochondrial matrix;GO:0005634//nucleus;GO:0005761//mitochondrial ribosome;GO:0005739//mitochondrion","NA","GO:0071850//mitotic cell cycle arrest;GO:1903862//positive regulation of oxidative phosphorylation;GO:0070126//mitochondrial translational termination;GO:0016032//viral process;GO:0008284//positive regulation of cell proliferation;GO:0070125//mitochondrial translational elongation","K22020//mucin-19","NP_443082.2//growth arrest and DNA damage-inducible proteins-interacting protein 1 [Homo sapiens]","3//A2MP1"]
[9168,482,2612.2,3692.38,0.499285675730629,{"v":1.38856657333333e-225,"d":"1.39E-225"},"*",{"v":2.08624e-228,"d":"2.09E-228"},"TMSB10","NA","NA","NA","K13785//thymosin beta 10","EAW99547.1//thymosin, beta 10, isoform CRA_a, partial [Homo sapiens]","3//A2MP1"]
[115701,7303,3.75,5.3,0.499101764067318,{"v":3.02452252941176E-6,"d":"3.02E-06"},"*",{"v":5.40756e-07,"d":"5.41E-07"},"ALPK2","GO:0005737//cytoplasm","GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding","NA","K08868//alpha-kinase","NP_443179.3//alpha-protein kinase 2 [Homo sapiens]","3//A2MP1"]
[11068,1414,11.45,16.18,0.498864009445671,0.000787709888,"*",0.00021574,"CYB561D2","NA","NA","NA","K08371//cytochrome b-561 domain containing protein 2","XP_014306202.1//PREDICTED: cytochrome b561 domain-containing protein 2 isoform X2 [Myotis lucifugus]","1//3;4"]
[257169,2091,0.46,0.65,0.498805856971442,0.514024695605381,"*",0.358794,"C9orf43","NA","NA","NA","K07524//regulator of G-protein signalling 3","NP_001265559.1//uncharacterized protein C9orf43 isoform 2 [Homo sapiens]","1//3;2//1"]
[222865,2841,1.09,1.54,0.498602215917975,0.147010700185943,"*",0.0742416,"TMEM130","GO:0005887//integral component of plasma membrane;GO:0005794//Golgi apparatus;GO:0000139//Golgi membrane","NA","NA","K04613//vomeronasal 2 receptor;K01064//wingless-type MMTV integration site family, member 9","XP_017389197.1//PREDICTED: transmembrane protein 130 isoform X2 [Cebus capucinus imitator];NP_001127923.1//transmembrane protein 130 isoform c precursor [Homo sapiens];XP_017389196.1//PREDICTED: transmembrane protein 130 isoform X1 [Cebus capucinus imitator]","1//3;2//1"]
[200172,2163,0.63,0.89,0.498453507466481,0.421856673463554,"*",0.277162,"SLFNL1","NA","GO:0005524//ATP binding","NA","K16628//collagen, type VII, alpha;K22020//mucin-19","NP_659427.3//schlafen-like protein 1 isoform 1 [Homo sapiens];NP_001287788.1//schlafen-like protein 1 isoform 2 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[54985,745,255.72,361.24,0.498392651911242,{"v":5.61587752727273e-36,"d":"5.62E-36"},"*",{"v":1.198832e-37,"d":"1.20E-37"},"HCFC1R1","GO:0005654//nucleoplasm;GO:0005737//cytoplasm","NA","NA","K09187//histone-lysine N-methyltransferase MLL2 [EC:2.1.1.43];K19475//WAS/WASL-interacting protein","NP_001275596.1//host cell factor C1 regulator 1 isoform 3 [Homo sapiens];XP_014688662.1//PREDICTED: host cell factor C1 regulator 1 isoform X1 [Equus asinus];XP_012297321.1//host cell factor C1 regulator 1 isoform X1 [Aotus nancymaae];NP_001002017.1//host cell factor C1 regulator 1 isoform 2 [Homo sapiens];NP_060355.1//host cell factor C1 regulator 1 isoform 1 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[7186,2298,15.95,22.53,0.498290889583196,{"v":7.11898550660793e-08,"d":"7.12E-08"},"*",{"v":1.01165E-8,"d":"1.01E-08"},"TRAF2","GO:0012506//vesicle membrane;GO:0045121//membrane raft;GO:0005938//cell cortex;GO:0005829//cytosol;GO:0009898//cytoplasmic side of plasma membrane;GO:1990604//IRE1-TRAF2-ASK1 complex;GO:0035631//CD40 receptor complex;GO:1990597//AIP1-IRE1 complex","GO:0042802//identical protein binding;GO:0005174//CD40 receptor binding;GO:0008270//zinc ion binding;GO:0031435//mitogen-activated protein kinase kinase kinase binding;GO:0019899//enzyme binding;GO:0004842//ubiquitin-protein transferase activity;GO:0032403//protein complex binding","GO:0097300//programmed necrotic cell death;GO:0051865//protein autoubiquitination;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0071732//cellular response to nitric oxide;GO:0051291//protein heterooligomerization;GO:1903721//positive regulation of I-kappaB phosphorylation;GO:0097296//activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:1903265//positive regulation of tumor necrosis factor-mediated signaling pathway;GO:0007250//activation of NF-kappaB-inducing kinase activity;GO:0034351//negative regulation of glial cell apoptotic process;GO:0030163//protein catabolic process;GO:0051023//regulation of immunoglobulin secretion;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0046328//regulation of JNK cascade;GO:0043623//cellular protein complex assembly","K03173//TNF receptor-associated factor 2 [EC:2.3.2.27]","XP_011517275.1//PREDICTED: TNF receptor-associated factor 2 isoform X1 [Homo sapiens]","3//A2MP1"]
[9274,1107,36.72,51.85,0.49777793028678,{"v":1.54271534070159E-8,"d":"1.54E-08"},"*",{"v":2.00976e-09,"d":"2.01E-09"},"BCL7C","NA","NA","GO:0006915//apoptotic process","K19719//collagen, type II, alpha;K06237//collagen, type IV, alpha;K13171//serine/arginine repetitive matrix protein 1;K19720//collagen, type III, alpha;K16882//protein piccolo","NP_001273455.1//B-cell CLL/lymphoma 7 protein family member C isoform 1 [Homo sapiens];NP_004756.2//B-cell CLL/lymphoma 7 protein family member C isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[23546,1029,1.36,1.92,0.497499659470817,0.42193708072048,"*",0.277162,"SYNGR4","GO:0030672//synaptic vesicle membrane;GO:0031594//neuromuscular junction;GO:0016021//integral component of membrane","NA","NA","K03006//DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6];K04403//TAK1-binding protein 1;K17783//mitochondrial FAD-linked sulfhydryl oxidase [EC:1.8.3.2];K21988//transmembrane channel-like protein","NP_036583.2//synaptogyrin-4 [Homo sapiens]","3//A2MP1"]
[146853,1034,0.56,0.79,0.496425826119499,0.634263715638236,"*",0.4781,"C17orf50","NA","NA","NA","K13172//serine/arginine repetitive matrix protein 2;K17498//transcription factor SPN1","XP_012640941.1//uncharacterized protein C17orf50 homolog isoform X4 [Microcebus murinus]","3//A2MP1"]
[8170,4167,0.95,1.34,0.496233582126825,0.112148641239821,"*",0.0534556,"SLC14A2","GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0050839//cell adhesion molecule binding;GO:0015204//urea transmembrane transporter activity","GO:0055085//transmembrane transport;GO:0015840//urea transport","K08716//solute carrier family 14 (urea transporter)","NP_009094.3//urea transporter 2 [Homo sapiens]","1//3;3//A2MP1"]
[95,1549,16.08,22.68,0.4961532337633,{"v":2.57890078657074E-5,"d":"2.58E-05"},"*",{"v":5.38576e-06,"d":"5.39E-06"},"ACY1","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0008237//metallopeptidase activity;GO:0042802//identical protein binding;GO:0004046//aminoacylase activity","GO:0006520//cellular amino acid metabolic process;GO:0006805//xenobiotic metabolic process","K14677//aminoacylase [EC:3.5.1.14]","NP_001185827.1//aminoacylase-1 isoform d [Homo sapiens];NP_001303260.1//ABHD14A-ACY1 readthrough (NMD candidate) [Homo sapiens];NP_001185826.1//aminoacylase-1 isoform c [Homo sapiens];NP_001185825.1//aminoacylase-1 isoform b [Homo sapiens]","1//3;2//1"]
[56915,1006,61.79,87.14,0.495961739812166,{"v":2.793846833213E-12,"d":"2.79E-12"},"*",{"v":2.42236E-13,"d":"2.42E-13"},"EXOSC5","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000176//nuclear exosome (RNase complex);GO:0035327//transcriptionally active chromatin;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0000177//cytoplasmic exosome (RNase complex);GO:0005829//cytosol;GO:0000178//exosome (RNase complex)","GO:0003723//RNA binding;GO:0000175//3'-5'-exoribonuclease activity","GO:0043928//exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay;GO:0031125//rRNA 3'-end processing;GO:0016075//rRNA catabolic process;GO:0034427//nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5';GO:0051607//defense response to virus;GO:0071028//nuclear mRNA surveillance;GO:0006364//rRNA processing;GO:0071051//polyadenylation-dependent snoRNA 3'-end processing;GO:0043488//regulation of mRNA stability;GO:0034475//U4 snRNA 3'-end processing;GO:0045006//DNA deamination","K12590//exosome complex component RRP46","AAM75154.1//chronic myelogenous leukemia tumor antigen 28 [Homo sapiens]","3//A2MP1"]
[79155,1807,13.95,19.67,0.49573183556198,{"v":9.76367779896486E-5,"d":"9.76E-05"},"*",{"v":2.2438e-05,"d":"2.24E-05"},"TNIP2","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0070530//K63-linked polyubiquitin modification-dependent protein binding;GO:0046872//metal ion binding;GO:0031593//polyubiquitin modification-dependent protein binding;GO:0019901//protein kinase binding","GO:0071222//cellular response to lipopolysaccharide;GO:0070498//interleukin-1-mediated signaling pathway;GO:0034134//toll-like receptor 2 signaling pathway;GO:0034162//toll-like receptor 9 signaling pathway;GO:0016579//protein deubiquitination;GO:0023035//CD40 signaling pathway;GO:0034138//toll-like receptor 3 signaling pathway;GO:0043032//positive regulation of macrophage activation;GO:0006351//transcription, DNA-templated;GO:0050871//positive regulation of B cell activation;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:0006915//apoptotic process;GO:0006954//inflammatory response;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0050821//protein stabilization;GO:0051403//stress-activated MAPK cascade","K10402//kinesin family member 20;K10352//myosin heavy chain;K16731//golgin subfamily A member 1;K07210//inhibitor of nuclear factor kappa-B kinase subunit gamma;K02990//small subunit ribosomal protein S6;K16456//centrosomal protein CEP55","XP_011914611.1//PREDICTED: TNFAIP3-interacting protein 2 isoform X2 [Cercocebus atys];NP_077285.3//TNFAIP3-interacting protein 2 isoform 1 [Homo sapiens];NP_001278945.1//TNFAIP3-interacting protein 2 isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[83886,1360,1.05,1.48,0.495207847962827,0.358069297683437,"*",0.219652,"PRSS27","GO:0005886//plasma membrane","GO:0004252//serine-type endopeptidase activity","NA","K09628//serine protease 27 [EC:3.4.21.-]","XP_004057067.1//PREDICTED: serine protease 27 isoform X1 [Gorilla gorilla gorilla]","4;1//3"]
[10475,5629,2.1,2.96,0.495207847962827,3.79288460540971E-3,"*",0.001193854,"TRIM38","GO:0005829//cytosol;GO:0005622//intracellular","GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0004871//signal transducer activity","GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0016567//protein ubiquitination;GO:0046598//positive regulation of viral entry into host cell","K12014//tripartite motif-containing protein 38 [EC:2.3.2.27]","NP_006346.1//E3 ubiquitin-protein ligase TRIM38 [Homo sapiens]",4]
[22921,1811,6.31,8.89,0.494543413847221,5.79491902184745E-3,"*",0.001892944,"MSRB2","GO:0005829//cytosol;GO:0005739//mitochondrion","GO:0003779//actin binding;GO:0033743//peptide-methionine (R)-S-oxide reductase activity;GO:0033745//L-methionine-(R)-S-oxide reductase activity;GO:0008270//zinc ion binding;GO:0003700//DNA binding transcription factor activity","GO:0006979//response to oxidative stress;GO:0030091//protein repair;GO:0030041//actin filament polymerization","K07305//peptide-methionine (R)-S-oxide reductase [EC:1.8.4.12]","XP_001155268.3//PREDICTED: methionine-R-sulfoxide reductase B2, mitochondrial [Pan troglodytes]","3//A2MP1"]
[51087,1606,0.86,1.21,0.492598482572497,0.421896873260911,"*",0.277162,"YBX2","GO:0005634//nucleus;GO:0001650//fibrillar center;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0003677//DNA binding","GO:0048599//oocyte development;GO:0006355//regulation of transcription, DNA-templated;GO:0009386//translational attenuation;GO:0007283//spermatogenesis;GO:0006366//transcription from RNA polymerase II promoter","K09277//Y-box-binding protein 2","NP_057066.2//Y-box-binding protein 2 [Homo sapiens]","3//A2MP1"]
[54958,696,27.96,39.33,0.492265825567474,0.000240985561378611,"*",{"v":5.95298E-5,"d":"5.95E-05"},"TMEM160","GO:0016021//integral component of membrane;GO:0005739//mitochondrion","NA","NA","K19720//collagen, type III, alpha","XP_003316511.2//PREDICTED: transmembrane protein 160 [Pan troglodytes]","1//3"]
[126328,824,113.3,159.35,0.492051157957338,{"v":9.40878360081466e-17,"d":"9.41E-17"},"*",{"v":5.78404e-18,"d":"5.78E-18"},"NDUFA11","GO:0005747//mitochondrial respiratory chain complex I;GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion","NA","GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0055114//oxidation-reduction process","K03956//NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 11","NP_783313.1//NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 isoform 1 [Homo sapiens];BAC87088.1//unnamed protein product [Homo sapiens]","4;1//3"]
[59340,3422,0.32,0.45,0.491853096329675,0.542758258420086,"*",0.388398,"HRH4","GO:0005623//cell;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004969//histamine receptor activity","GO:0007194//negative regulation of adenylate cyclase activity;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0043408//regulation of MAPK cascade;GO:0006954//inflammatory response","K04152//histamine receptor H4","NP_001137300.1//histamine H4 receptor isoform 2 [Homo sapiens];NP_067637.2//histamine H4 receptor isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[50855,1270,1.28,1.8,0.491853096329675,0.392537189465409,"*",0.25006,"PARD6A","NA","NA","NA","K06093//partitioning defective protein 6","EAW83152.1//hCG2025821, isoform CRA_b [Homo sapiens]","1//3;2//1"]
[54461,2390,42.89,60.31,0.491755919224471,{"v":6.6602956503856e-20,"d":"6.66E-20"},"*",{"v":3.24384E-21,"d":"3.24E-21"},"FBXW5","GO:0080008//Cul4-RING E3 ubiquitin ligase complex;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0019005//SCF ubiquitin ligase complex","GO:0004842//ubiquitin-protein transferase activity;GO:0019901//protein kinase binding","GO:0043687//post-translational protein modification;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0010824//regulation of centrosome duplication;GO:0007088//regulation of mitotic nuclear division;GO:0000209//protein polyubiquitination","K10263//F-box and WD-40 domain protein 5","XP_008003741.1//PREDICTED: F-box/WD repeat-containing protein 5 [Chlorocebus sabaeus]","3//A2MP1"]
[613037,3904,31.15,43.79,0.491369286541287,{"v":1.44018965311475e-23,"d":"1.44E-23"},"*",{"v":5.49966E-25,"d":"5.50E-25"},"NPIPB13","GO:0005654//nucleoplasm;GO:0016021//integral component of membrane","NA","NA","K09187//histone-lysine N-methyltransferase MLL2 [EC:2.1.1.43]","NP_001308821.1//nuclear pore complex-interacting protein family member B13 [Homo sapiens]","1//3"]
[79144,832,326.96,459.59,0.491233258939792,{"v":1.60021087553648E-49,"d":"1.60E-49"},"*",{"v":2.3341e-51,"d":"2.33E-51"},"PPDPF","NA","NA","GO:0001708//cell fate specification;GO:0031017//exocrine pancreas development","K13909//mucin-7;K05853//Ca2+ transporting ATPase, sarcoplasmic/endoplasmic reticulum [EC:3.6.3.8];K02599//Notch 1","XP_011789835.1//PREDICTED: pancreatic progenitor cell differentiation and proliferation factor [Colobus angolensis palliatus];XP_017355202.1//PREDICTED: uncharacterized protein LOC108283384 [Cebus capucinus imitator]","1//3;3//A2MP1"]
[4487,1940,4.39,6.17,0.49104954961406,0.0182113299173554,"*",0.00675942,"MSX1","GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0000982//transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0002039//p53 binding;GO:0043565//sequence-specific DNA binding;GO:0035326//enhancer binding;GO:0001227//transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding","GO:0071316//cellular response to nicotine;GO:0090427//activation of meiosis;GO:0030513//positive regulation of BMP signaling pathway;GO:0035880//embryonic nail plate morphogenesis;GO:0061312//BMP signaling pathway involved in heart development;GO:0042474//middle ear morphogenesis;GO:0021983//pituitary gland development;GO:0051154//negative regulation of striated muscle cell differentiation;GO:0043517//positive regulation of DNA damage response, signal transduction by p53 class mediator;GO:0008285//negative regulation of cell proliferation;GO:0061180//mammary gland epithelium development;GO:0060349//bone morphogenesis;GO:0035116//embryonic hindlimb morphogenesis;GO:0043066//negative regulation of apoptotic process;GO:0042475//odontogenesis of dentin-containing tooth;GO:0030900//forebrain development;GO:0007275//multicellular organism development;GO:0009952//anterior/posterior pattern specification;GO:2000678//negative regulation of transcription regulatory region DNA binding;GO:0003198//epithelial to mesenchymal transition involved in endocardial cushion formation;GO:0030901//midbrain development;GO:0006355//regulation of transcription, DNA-templated;GO:0023019//signal transduction involved in regulation of gene expression;GO:0060536//cartilage morphogenesis;GO:0060021//palate development;GO:0042481//regulation of odontogenesis;GO:0010463//mesenchymal cell proliferation;GO:0000902//cell morphogenesis;GO:0030308//negative regulation of cell growth;GO:0006351//transcription, DNA-templated;GO:0001701//in utero embryonic development;GO:0007517//muscle organ development;GO:2001055//positive regulation of mesenchymal cell apoptotic process;GO:0035115//embryonic forelimb morphogenesis;GO:0048863//stem cell differentiation;GO:0060325//face morphogenesis;GO:1902255//positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator;GO:0034504//protein localization to nucleus;GO:0050821//protein stabilization","K09341//homeobox protein MSX","NP_002439.2//homeobox protein MSX-1 [Homo sapiens]","3//A2MP1"]
[84179,2108,0.37,0.52,0.490986352512142,0.578782204572804,"*",0.421532,"SLC49A3","GO:0016021//integral component of membrane","NA","GO:0055085//transmembrane transport","K12306//MFS transporter, FLVCR family, MFS-domain-containing protein 7","NP_115595.2//major facilitator superfamily domain-containing protein 7 isoform 2 [Homo sapiens];NP_001281270.1//major facilitator superfamily domain-containing protein 7 isoform 1 [Homo sapiens];NP_001281271.1//major facilitator superfamily domain-containing protein 7 isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[6193,755,703.32,987.67,0.489847846321682,{"v":3.533225164e-95,"d":"3.53E-95"},"*",{"v":2.21186E-97,"d":"2.21E-97"},"RPS5","NA","NA","NA","K02989//small subunit ribosomal protein S5e","XP_017706028.1//PREDICTED: 40S ribosomal protein S5 isoform X1 [Rhinopithecus bieti]","3//A2MP1"]
[363,2654,1.41,1.98,0.489805267680816,0.16997556450677,"*",0.0880204,"AQP6","NA","NA","NA","K09868//aquaporin-6","XP_008001382.1//PREDICTED: aquaporin-6 [Chlorocebus sabaeus]","3//A2MP1"]
[6999,1703,0.57,0.8,0.489038080722621,0.514116913885899,"*",0.358794,"TDO2","GO:0005829//cytosol","GO:0046872//metal ion binding;GO:0020037//heme binding;GO:0016597//amino acid binding;GO:0042802//identical protein binding;GO:0004833//tryptophan 2,3-dioxygenase activity;GO:0019825//oxygen binding","GO:0019442//tryptophan catabolic process to acetyl-CoA;GO:0051289//protein homotetramerization;GO:0006569//tryptophan catabolic process;GO:0019441//tryptophan catabolic process to kynurenine","K00453//tryptophan 2,3-dioxygenase [EC:1.13.11.11]","NP_005642.1//tryptophan 2,3-dioxygenase [Homo sapiens]","3//A2MP1"]
[100505549,2012,2.28,3.2,0.489038080722621,0.103336429801413,"*",0.0485372,"LOC100505549","NA","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K06245//laminin, beta 4;K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9]","NP_001229733.1//uncharacterized protein LOC100505549 [Homo sapiens]","1//3"]
[7920,2025,6.8,9.54,0.48845451986781,0.00205563942448464,"*",0.000611776,"ABHD16A","GO:0016021//integral component of membrane","GO:0047372//acylglycerol lipase activity","GO:0052651//monoacylglycerol catabolic process;GO:1905344//prostaglandin catabolic process","K08869//aarF domain-containing kinase","XP_004043725.2//PREDICTED: protein ABHD16A isoform X1 [Gorilla gorilla gorilla];NP_001170986.1//protein ABHD16A isoform b [Homo sapiens]","1//3;2//1"]
[22904,4948,23.23,32.56,0.48711154545744,{"v":5.17122160592593e-22,"d":"5.17E-22"},"*",{"v":2.18516E-23,"d":"2.19E-23"},"SBNO2","NA","NA","GO:0045892//negative regulation of transcription, DNA-templated;GO:0030282//bone mineralization;GO:0071222//cellular response to lipopolysaccharide;GO:0006351//transcription, DNA-templated;GO:0072675//osteoclast fusion;GO:0061430//bone trabecula morphogenesis;GO:0050727//regulation of inflammatory response;GO:1990830//cellular response to leukemia inhibitory factor;GO:0071354//cellular response to interleukin-6;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0002281//macrophage activation involved in immune response;GO:0071348//cellular response to interleukin-11","K16628//collagen, type VII, alpha","NP_055778.2//protein strawberry notch homolog 2 isoform 1 [Homo sapiens];NP_001093592.1//protein strawberry notch homolog 2 isoform 2 [Homo sapiens]","1//3;2//1"]
[1471,947,221.57,310.52,0.486923635204928,{"v":1.998539088e-35,"d":"2.00E-35"},"*",{"v":4.37892e-37,"d":"4.38E-37"},"CST3","GO:1904724//tertiary granule lumen;GO:0070062//extracellular exosome;GO:0005788//endoplasmic reticulum lumen;GO:0030424//axon;GO:0005783//endoplasmic reticulum;GO:0031965//nuclear membrane;GO:0005615//extracellular space;GO:0005764//lysosome;GO:0043292//contractile fiber;GO:0048471//perinuclear region of cytoplasm;GO:0043025//neuronal cell body;GO:0005771//multivesicular body;GO:0005576//extracellular region;GO:1904813//ficolin-1-rich granule lumen;GO:0005604//basement membrane","GO:0002020//protease binding;GO:0001540//amyloid-beta binding;GO:0042802//identical protein binding;GO:0004866//endopeptidase inhibitor activity;GO:0004869//cysteine-type endopeptidase inhibitor activity","GO:0043687//post-translational protein modification;GO:0060311//negative regulation of elastin catabolic process;GO:0007420//brain development;GO:0007566//embryo implantation;GO:0043067//regulation of programmed cell death;GO:0044267//cellular protein metabolic process;GO:0007431//salivary gland development;GO:0032355//response to estradiol;GO:0034103//regulation of tissue remodeling;GO:0010716//negative regulation of extracellular matrix disassembly;GO:0070301//cellular response to hydrogen peroxide;GO:0042493//response to drug;GO:0010466//negative regulation of peptidase activity;GO:0001654//eye development;GO:0060313//negative regulation of blood vessel remodeling;GO:0045740//positive regulation of DNA replication;GO:0001666//response to hypoxia;GO:0006915//apoptotic process;GO:2000117//negative regulation of cysteine-type endopeptidase activity;GO:0042747//circadian sleep/wake cycle, REM sleep;GO:0009743//response to carbohydrate;GO:0045861//negative regulation of proteolysis;GO:0010711//negative regulation of collagen catabolic process;GO:0009636//response to toxic substance;GO:0043312//neutrophil degranulation;GO:0048678//response to axon injury;GO:0060009//Sertoli cell development;GO:0001775//cell activation;GO:0006952//defense response;GO:0031667//response to nutrient levels;GO:0060548//negative regulation of cell death;GO:0097435//supramolecular fiber organization;GO:0008284//positive regulation of cell proliferation","K13899//cystatin-C","NP_000090.1//cystatin-C precursor [Homo sapiens]","1//3;3//A2MP1"]
[113675,1427,8.32,11.66,0.486912355059404,0.0048884352,"*",0.001574496,"SDSL","GO:0070062//extracellular exosome;GO:0005739//mitochondrion","GO:0003941//L-serine ammonia-lyase activity;GO:0042802//identical protein binding;GO:0030170//pyridoxal phosphate binding;GO:0004794//L-threonine ammonia-lyase activity","GO:0006520//cellular amino acid metabolic process","K17989//L-serine/L-threonine ammonia-lyase [EC:4.3.1.17 4.3.1.19]","XP_016874252.1//PREDICTED: serine dehydratase-like isoform X1 [Homo sapiens]","1//3;3//A2MP1"]
[10979,3351,14.9,20.88,0.48680938122036,{"v":4.86964520973349e-10,"d":"4.87E-10"},"*",{"v":5.26168e-11,"d":"5.26E-11"},"FERMT2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005925//focal adhesion;GO:0005938//cell cortex;GO:0005737//cytoplasm;GO:0031258//lamellipodium membrane;GO:0001725//stress fiber;GO:0009986//cell surface;GO:0005829//cytosol;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0031674//I band;GO:0031941//filamentous actin","GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding","GO:0034329//cell junction assembly;GO:0034446//substrate adhesion-dependent cell spreading;GO:0072657//protein localization to membrane;GO:0008360//regulation of cell shape;GO:0033622//integrin activation;GO:0007160//cell-matrix adhesion;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0016055//Wnt signaling pathway;GO:0007229//integrin-mediated signaling pathway;GO:0048041//focal adhesion assembly","K17083//kindlin 2","XP_006076361.1//PREDICTED: fermitin family homolog 2 isoform X3 [Bubalus bubalis];NP_001128472.1//fermitin family homolog 2 isoform 3 [Homo sapiens];CAA80852.1//mitogen inducible gene mig-2, partial [Homo sapiens]","1//3;2//1"]
[10669,1123,5.27,7.38,0.485817854423181,0.0382321173182305,"*",0.01563606,"CGREF1","GO:0005576//extracellular region","GO:0005509//calcium ion binding","GO:0007155//cell adhesion;GO:0006950//response to stress;GO:0007050//cell cycle arrest;GO:0008285//negative regulation of cell proliferation","K03006//DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6];K19538//retinitis pigmentosa 1;K00846//ketohexokinase [EC:2.7.1.3];K06831//galectin-3","NP_006560.3//cell growth regulator with EF hand domain protein 1 isoform a precursor [Homo sapiens];EAX00636.1//cell growth regulator with EF-hand domain 1, isoform CRA_b [Homo sapiens]","1//3;5"]
[170954,4035,18.29,25.61,0.485652177848752,{"v":1.29061285405405E-7,"d":"1.29E-07"},"*",{"v":1.883322e-08,"d":"1.88E-08"},"PPP1R18","GO:0005856//cytoskeleton;GO:0005737//cytoplasm","GO:0003779//actin binding;GO:0019902//phosphatase binding","NA","K17559//phostensin","NP_597728.1//phostensin [Homo sapiens]","1//3;3//A2MP1"]
[388021,3336,0.05,0.07,0.485426827170242,0.782535412159749,"*",0.685686,"TMEM179","GO:0016021//integral component of membrane","NA","NA","K03006//DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6];K09312//homeobox protein CDX1/4;K06840//semaphorin 3;K19607//X-linked retinitis pigmentosa GTPase regulator","EAW81868.1//FLJ42486 protein, isoform CRA_b [Homo sapiens];XP_012353428.1//PREDICTED: transmembrane protein 179 isoform X2 [Nomascus leucogenys]","1//3"]
[1757,3234,0.05,0.07,0.485426827170242,0.782255975146408,"*",0.685686,"SARDH","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0008480//sarcosine dehydrogenase activity;GO:0016491//oxidoreductase activity","GO:1901053//sarcosine catabolic process;GO:0042426//choline catabolic process","K00314//sarcosine dehydrogenase [EC:1.5.8.3]","NP_009032.2//sarcosine dehydrogenase, mitochondrial precursor [Homo sapiens]","1//3;3//A2MP1"]
[283229,1848,1.2,1.68,0.485426827170242,0.397779978696621,"*",0.25716,"CRACR2B","GO:0005737//cytoplasm","GO:0005509//calcium ion binding","GO:2001256//regulation of store-operated calcium entry;GO:0034613//cellular protein localization;GO:0002115//store-operated calcium entry","K17199//Ras and EF-hand domain-containing protein","EAX02397.1//hypothetical protein MGC45840, isoform CRA_a, partial [Homo sapiens];NP_775855.3//EF-hand calcium-binding domain-containing protein 4A isoform 2 [Homo sapiens]","1//3;4"]
[122953,3843,6.05,8.47,0.485426827170242,{"v":1.95665560331593E-5,"d":"1.96E-05"},"*",{"v":3.9895e-06,"d":"3.99E-06"},"JDP2","GO:0005634//nucleus","GO:0003677//DNA binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0046982//protein heterodimerization activity;GO:0003700//DNA binding transcription factor activity;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0031065//positive regulation of histone deacetylation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0031063//regulation of histone deacetylation;GO:0006351//transcription, DNA-templated;GO:0045599//negative regulation of fat cell differentiation","K09033//jun dimerization protein 2","XP_005343429.2//PREDICTED: LOW QUALITY PROTEIN: jun dimerization protein 2 [Microtus ochrogaster];XP_016876460.1//PREDICTED: jun dimerization protein 2 isoform X1 [Homo sapiens];NP_001128521.1//jun dimerization protein 2 isoform b [Homo sapiens];XP_011763810.1//PREDICTED: jun dimerization protein 2 isoform X1 [Macaca nemestrina]","1//3;3//A2MP1"]
[51393,2829,0.2,0.28,0.485426827170242,0.634474486998422,"*",0.4781,"TRPV2","GO:0044295//axonal growth cone;GO:0005622//intracellular;GO:0042470//melanosome;GO:0032584//growth cone membrane;GO:0044297//cell body;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005216//ion channel activity;GO:0015075//ion transmembrane transporter activity;GO:0005262//calcium channel activity;GO:0005261//cation channel activity","GO:0006810//transport;GO:0045773//positive regulation of axon extension;GO:0070588//calcium ion transmembrane transport;GO:0090280//positive regulation of calcium ion import;GO:0007600//sensory perception;GO:0009408//response to heat;GO:0009266//response to temperature stimulus","K04971//transient receptor potential cation channel subfamily V member 2","NP_057197.2//transient receptor potential cation channel subfamily V member 2 [Homo sapiens]",4]
[143630,2350,0.1,0.14,0.485426827170242,0.81066903005254,"*",0.724446,"UBQLNL","NA","NA","NA","K22254//ubiquilin-like protein","BAC87218.1//unnamed protein product [Homo sapiens]",4]
[6768,3319,0.05,0.07,0.485426827170242,0.780861778284737,"*",0.685686,"ST14","GO:0070062//extracellular exosome;GO:0016323//basolateral plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0019897//extrinsic component of plasma membrane","GO:0004252//serine-type endopeptidase activity;GO:0004175//endopeptidase activity;GO:0008236//serine-type peptidase activity","GO:0006508//proteolysis;GO:0030216//keratinocyte differentiation;GO:0001843//neural tube closure;GO:0060672//epithelial cell morphogenesis involved in placental branching;GO:0070268//cornification","K08670//suppressor of tumorigenicity protein 14 [EC:3.4.21.109]","NP_068813.1//suppressor of tumorigenicity 14 protein [Homo sapiens]","3//A2MP1"]
[168507,9092,0.05,0.07,0.485426827170242,0.718247874460806,"*",0.60458,"PKD1L1","GO:0016020//membrane;GO:0005929//cilium;GO:0060170//ciliary membrane;GO:0034704//calcium channel complex;GO:0097730//non-motile cilium","GO:0005262//calcium channel activity","GO:0098609//cell-cell adhesion;GO:0070986//left/right axis specification;GO:0050982//detection of mechanical stimulus;GO:0003127//detection of nodal flow","K04987//polycystin 1L1","XP_016867287.1//PREDICTED: polycystic kidney disease protein 1-like 1 isoform X1 [Homo sapiens]",4]
[55786,2673,0.65,0.91,0.485426827170242,0.344778488540161,"*",0.20906,"ZNF415","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_012613294.1//zinc finger protein 415 isoform X3 [Microcebus murinus];XP_012613292.1//zinc finger protein 415 isoform X2 [Microcebus murinus];XP_012613289.1//zinc finger protein 415 isoform X1 [Microcebus murinus]","1//3;3//A2MP1;2//1"]
[4015,4159,0.15,0.21,0.485426827170242,0.557704874924052,"*",0.402236,"LOX","GO:0005634//nucleus;GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005578//proteinaceous extracellular matrix","GO:0005507//copper ion binding;GO:0004720//protein-lysine 6-oxidase activity","GO:0030324//lung development;GO:0042493//response to drug;GO:0007507//heart development;GO:0042060//wound healing;GO:0030199//collagen fibril organization;GO:0048251//elastic fiber assembly;GO:0048545//response to steroid hormone;GO:0006464//cellular protein modification process;GO:0048514//blood vessel morphogenesis;GO:0030198//extracellular matrix organization;GO:0035904//aorta development","K00277//protein-lysine 6-oxidase [EC:1.4.3.13]","NP_002308.2//protein-lysine 6-oxidase isoform 1 preproprotein [Homo sapiens];XP_017715216.1//PREDICTED: protein-lysine 6-oxidase [Rhinopithecus bieti]","6;1//3;2//1"]
[2644,713,2.95,4.13,0.485426827170242,0.328953406948357,"*",0.1973844,"GCHFR","GO:0030425//dendrite;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0042470//melanosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043234//protein complex","GO:0016787//hydrolase activity;GO:0016597//amino acid binding;GO:0030742//GTP-dependent protein binding;GO:0004857//enzyme inhibitor activity;GO:0044549//GTP cyclohydrolase binding","GO:0051291//protein heterooligomerization;GO:0042133//neurotransmitter metabolic process;GO:0009890//negative regulation of biosynthetic process;GO:0043105//negative regulation of GTP cyclohydrolase I activity;GO:0050999//regulation of nitric-oxide synthase activity;GO:0006809//nitric oxide biosynthetic process","NA","XP_019500533.1//PREDICTED: GTP cyclohydrolase 1 feedback regulatory protein [Hipposideros armiger]","2//1"]
[254263,1356,2.1,2.94,0.485426827170242,0.227062239432177,"*",0.1261678,"CNIH2","GO:0016021//integral component of membrane;GO:0043197//dendritic spine;GO:0014069//postsynaptic density","NA","GO:0006810//transport;GO:2000311//regulation of AMPA receptor activity","K20368//protein cornichon","XP_012612935.2//protein cornichon homolog 2 [Microcebus murinus]","2//1"]
[7053,2679,0.15,0.21,0.485426827170242,0.695269131036558,"*",0.578622,"TGM3","GO:0070062//extracellular exosome;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0005737//cytoplasm","GO:0016746//transferase activity, transferring acyl groups;GO:0005509//calcium ion binding;GO:0003824//catalytic activity;GO:0003810//protein-glutamine gamma-glutamyltransferase activity","GO:0018149//peptide cross-linking;GO:0043163//cell envelope organization;GO:0031069//hair follicle morphogenesis;GO:0006464//cellular protein modification process;GO:0030216//keratinocyte differentiation;GO:0051262//protein tetramerization;GO:0031424//keratinization","K05620//transglutaminase 3 [EC:2.3.2.13]","NP_003236.3//protein-glutamine gamma-glutamyltransferase E [Homo sapiens]","3//A2MP1"]
[283,742,7.19,10.06,0.484566629366229,0.0762012853474742,"*",0.0341842,"ANG","GO:0070062//extracellular exosome;GO:0005605//basal lamina;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0031410//cytoplasmic vesicle;GO:0032311//angiogenin-PRI complex;GO:0043025//neuronal cell body;GO:0030426//growth cone;GO:0005730//nucleolus;GO:0005576//extracellular region","GO:0003677//DNA binding;GO:0005102//receptor binding;GO:0042277//peptide binding;GO:0042803//protein homodimerization activity;GO:0003676//nucleic acid binding;GO:0003779//actin binding;GO:0005507//copper ion binding;GO:0008201//heparin binding;GO:0004540//ribonuclease activity;GO:0004519//endonuclease activity;GO:0019843//rRNA binding","GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0032148//activation of protein kinase B activity;GO:0016477//cell migration;GO:0001890//placenta development;GO:0032431//activation of phospholipase A2 activity;GO:0017148//negative regulation of translation;GO:0001938//positive regulation of endothelial cell proliferation;GO:0050830//defense response to Gram-positive bacterium;GO:0001878//response to yeast;GO:0045087//innate immune response;GO:0030041//actin filament polymerization;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0042592//homeostatic process;GO:0030154//cell differentiation;GO:0001525//angiogenesis;GO:0007154//cell communication;GO:0006651//diacylglycerol biosynthetic process;GO:0001556//oocyte maturation;GO:0001541//ovarian follicle development;GO:0001666//response to hypoxia;GO:0050714//positive regulation of protein secretion;GO:0034332//adherens junction organization;GO:0042327//positive regulation of phosphorylation;GO:0019732//antifungal humoral response;GO:0007202//activation of phospholipase C activity;GO:0009725//response to hormone;GO:0009303//rRNA transcription;GO:0019731//antibacterial humoral response","K16631//angiogenin [EC:3.1.27.-]","NP_001136.1//angiogenin precursor [Homo sapiens];EAW66445.1//hCG2044783, isoform CRA_a [Homo sapiens]","4;2//1"]
[11135,2182,43.69,61.12,0.484341437591531,{"v":5.78005357765363e-18,"d":"5.78E-18"},"*",{"v":3.23848e-19,"d":"3.24E-19"},"CDC42EP1","GO:0012505//endomembrane system;GO:0005856//cytoskeleton;GO:0005925//focal adhesion;GO:0005913//cell-cell adherens junction;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0098641//cadherin binding involved in cell-cell adhesion;GO:0017049//GTP-Rho binding;GO:0005096//GTPase activator activity","GO:0007266//Rho protein signal transduction;GO:0031274//positive regulation of pseudopodium assembly;GO:0030838//positive regulation of actin filament polymerization;GO:0008360//regulation of cell shape","K12826//splicing factor 3A subunit 2","NP_689449.1//cdc42 effector protein 1 [Homo sapiens]","2//1"]
[342897,1973,1.63,2.28,0.484161859933664,0.191752823121387,"*",0.1017584,"NCCRP1","GO:0070062//extracellular exosome;GO:0005737//cytoplasm","NA","GO:0008284//positive regulation of cell proliferation","K02927//large subunit ribosomal protein L40e;K10102//F-box protein 27;K15696//RING finger protein 113B;K17985//activating molecule in BECN1-regulated autophagy protein 1;K01064//wingless-type MMTV integration site family, member 9","NP_001001414.1//F-box only protein 50 [Homo sapiens]","1//3"]
[51548,1462,21.49,30.05,0.483699508170765,{"v":2.05918493361884e-05,"d":"2.06E-05"},"*",{"v":4.21402e-06,"d":"4.21E-06"},"SIRT6","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005724//nuclear telomeric heterochromatin;GO:0005737//cytoplasm","GO:0003714//transcription corepressor activity;GO:0017136//NAD-dependent histone deacetylase activity;GO:0003950//NAD+ ADP-ribosyltransferase activity;GO:0070403//NAD+ binding;GO:0003682//chromatin binding;GO:0046969//NAD-dependent histone deacetylase activity (H3-K9 specific);GO:0008270//zinc ion binding;GO:0034979//NAD-dependent protein deacetylase activity;GO:0003956//NAD(P)+-protein-arginine ADP-ribosyltransferase activity","GO:0006284//base-excision repair;GO:1905564//positive regulation of vascular endothelial cell proliferation;GO:0031940//positive regulation of chromatin silencing at telomere;GO:1902732//positive regulation of chondrocyte proliferation;GO:0010569//regulation of double-strand break repair via homologous recombination;GO:0042593//glucose homeostasis;GO:2000648//positive regulation of stem cell proliferation;GO:0003247//post-embryonic cardiac muscle cell growth involved in heart morphogenesis;GO:0031648//protein destabilization;GO:0006471//protein ADP-ribosylation;GO:0008285//negative regulation of cell proliferation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0046325//negative regulation of glucose import;GO:1905555//positive regulation blood vessel branching;GO:0048146//positive regulation of fibroblast proliferation;GO:0032206//positive regulation of telomere maintenance;GO:0031667//response to nutrient levels;GO:0045820//negative regulation of glycolytic process;GO:1905549//positive regulation of telomeric heterochromatin assembly","K11416//mono-ADP-ribosyltransferase sirtuin 6 [EC:2.4.2.31]","NP_001307988.1//NAD-dependent protein deacetylase sirtuin-6 isoform 4 [Homo sapiens];XP_016790192.1//PREDICTED: NAD-dependent protein deacetylase sirtuin-6 isoform X5 [Pan troglodytes];NP_001180214.1//NAD-dependent protein deacetylase sirtuin-6 isoform 2 [Homo sapiens];NP_001307989.1//NAD-dependent protein deacetylase sirtuin-6 isoform 5 [Homo sapiens];NP_057623.2//NAD-dependent protein deacetylase sirtuin-6 isoform 1 [Homo sapiens];XP_011822746.1//PREDICTED: NAD-dependent protein deacetylase sirtuin-6 isoform X4 [Mandrillus leucophaeus]","1//3;3//A2MP1;2//1"]
[401115,439,72.66,101.6,0.483667131244043,{"v":5.87814369919786E-6,"d":"5.88E-06"},"*",{"v":1.101002E-6,"d":"1.10E-06"},"C4orf48","NA","NA","NA","NA","NP_001161715.1//neuropeptide-like protein C4orf48 isoform 1 [Homo sapiens]","1//3;2//1"]
[389203,1021,8.3,11.6,0.482941563780647,0.022779547554535,"*",0.00869456,"SMIM20","NA","NA","NA","NA","XP_008950444.1//PREDICTED: LOW QUALITY PROTEIN: small integral membrane protein 20 [Pan paniscus]","1//3"]
[164633,3001,1.46,2.04,0.482600783091478,0.114281172802306,"*",0.054608,"CABP7","GO:0032588//trans-Golgi network membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0048471//perinuclear region of cytoplasm","GO:0005509//calcium ion binding","NA","K13152//U11/U12 small nuclear ribonucleoprotein 20 kDa protein","XP_017711107.1//PREDICTED: calcium-binding protein 7 [Rhinopithecus bieti]","2//1"]
[348262,1271,69.49,97.04,0.481774169577941,{"v":7.53245876099426e-16,"d":"7.53E-16"},"*",{"v":4.93236e-17,"d":"4.93E-17"},"MCRIP1","NA","NA","NA","K17566//protein phosphatase 1 regulatory subunit 27","XP_008954745.1//PREDICTED: protein FAM195B isoform X2 [Pan paniscus];XP_008011458.1//PREDICTED: protein FAM195B isoform X1 [Chlorocebus sabaeus];XP_017734734.1//PREDICTED: mapk-regulated corepressor-interacting protein 1 isoform X4 [Rhinopithecus bieti]","1//3;4;2//1"]
[10581,738,59.88,83.6,0.481428720909828,{"v":2.27852410596027E-8,"d":"2.28E-08"},"*",{"v":3.0154e-09,"d":"3.02E-09"},"IFITM2","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","NA","GO:0035456//response to interferon-beta;GO:0060337//type I interferon signaling pathway;GO:0051607//defense response to virus;GO:0046597//negative regulation of viral entry into host cell;GO:0035455//response to interferon-alpha;GO:0045071//negative regulation of viral genome replication;GO:0034341//response to interferon-gamma;GO:0006955//immune response;GO:0009615//response to virus","K06566//interferon induced transmembrane protein","NP_006426.2//interferon-induced transmembrane protein 2 [Homo sapiens]","2//1"]
[6320,1423,8.61,12.02,0.481351753314342,0.00468175885413417,"*",1.502946E-3,"CLEC11A","GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0008083//growth factor activity;GO:0030246//carbohydrate binding","GO:0001503//ossification;GO:0008284//positive regulation of cell proliferation","K17521//C-type lectin domain family 11 member A","XP_007995878.1//PREDICTED: C-type lectin domain family 11 member A [Chlorocebus sabaeus]","2//1"]
[126208,2039,56.03,78.18,0.4806000920591,{"v":4.12384603502825e-21,"d":"4.12E-21"},"*",{"v":1.827772e-22,"d":"1.83E-22"},"ZNF787","GO:0005581//collagen trimer;GO:0005604//basement membrane","GO:0005201//extracellular matrix structural constituent","NA","K09228//KRAB domain-containing zinc finger protein;K16628//collagen, type VII, alpha","XP_009465419.1//PREDICTED: zinc finger protein 629-like, partial [Nipponia nippon];NP_001338611.1//zinc finger protein 787 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[7483,4012,0.81,1.13,0.480328959530563,0.197497477754287,"*",0.1052644,"WNT9A","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix","GO:0048018//receptor ligand activity;GO:0005102//receptor binding;GO:0005109//frizzled binding","GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0072498//embryonic skeletal joint development;GO:0045597//positive regulation of cell differentiation;GO:0008285//negative regulation of cell proliferation;GO:0045165//cell fate commitment;GO:0030182//neuron differentiation;GO:0007267//cell-cell signaling;GO:0061303//cornea development in camera-type eye;GO:0035115//embryonic forelimb morphogenesis;GO:0061072//iris morphogenesis;GO:0071300//cellular response to retinoic acid;GO:0007093//mitotic cell cycle checkpoint;GO:0060070//canonical Wnt signaling pathway;GO:0032331//negative regulation of chondrocyte differentiation;GO:0048704//embryonic skeletal system morphogenesis;GO:0007275//multicellular organism development;GO:0045880//positive regulation of smoothened signaling pathway;GO:0016055//Wnt signaling pathway","K01064//wingless-type MMTV integration site family, member 9","NP_003386.1//protein Wnt-9a precursor [Homo sapiens]","3//A2MP1"]
[83475,1868,8.33,11.62,0.480221668038981,0.000516309536527514,"*",0.000136269,"DOHH","GO:0005829//cytosol","GO:0046872//metal ion binding;GO:0019135//deoxyhypusine monooxygenase activity","GO:0008612//peptidyl-lysine modification to peptidyl-hypusine","K06072//deoxyhypusine monooxygenase [EC:1.14.99.29]","NP_112594.1//deoxyhypusine hydroxylase [Homo sapiens]","1//3;4"]
[10195,1571,72.17,100.64,0.479732667453577,{"v":1.28299891282051e-20,"d":"1.28E-20"},"*",{"v":5.95156e-22,"d":"5.95E-22"},"ALG3","GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0000033//alpha-1,3-mannosyltransferase activity;GO:0052925//dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity","GO:0006486//protein glycosylation;GO:0006488//dolichol-linked oligosaccharide biosynthetic process","K03845//alpha-1,3-mannosyltransferase [EC:2.4.1.258]","NP_001006942.1//dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase isoform d [Homo sapiens];NP_005778.1//dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase isoform a [Homo sapiens]","2//1;5"]
[51079,557,93.43,130.25,0.479325599449479,{"v":2.19655761756829e-09,"d":"2.20E-09"},"*",{"v":2.56728e-10,"d":"2.57E-10"},"NDUFA13","GO:0016021//integral component of membrane","NA","NA","K11353//NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 13","EAW84826.1//NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 [Homo sapiens]",6]
[127579,2421,0.33,0.46,0.47916783669856,0.578682723272602,"*",0.421532,"DCST2","GO:0016021//integral component of membrane","NA","NA","K14315//nucleoporin NDC1;K06836//disintegrin and metalloproteinase domain-containing protein 15 [EC:3.4.24.-]","NP_653223.2//DC-STAMP domain-containing protein 2 [Homo sapiens]","2//1"]
[51063,1966,0.94,1.31,0.478834149859813,0.365188326117742,"*",0.226008,"CALHM2","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane","GO:0005261//cation channel activity","GO:0034220//ion transmembrane transport","K19739//calcium homeostasis modulator protein 2","NP_057000.2//calcium homeostasis modulator protein 2 [Homo sapiens]",4]
[56925,1132,9.55,13.3,0.477853607465441,0.00943924002186191,"*",0.00324352,"LXN","GO:0070062//extracellular exosome;GO:0005737//cytoplasm","GO:0008191//metalloendopeptidase inhibitor activity;GO:0008201//heparin binding","GO:0050965//detection of temperature stimulus involved in sensory perception of pain;GO:0006954//inflammatory response","NA","NP_064554.3//latexin [Homo sapiens]","3//A2MP1"]
[5441,925,310.66,432.63,0.477797215325592,{"v":1.07768315586207e-49,"d":"1.08E-49"},"*",{"v":1.565184e-51,"d":"1.57E-51"},"POLR2L","NA","GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0003677//DNA binding;GO:0008270//zinc ion binding","GO:0006351//transcription, DNA-templated","K03007//DNA-directed RNA polymerases I, II, and III subunit RPABC5","XP_017704120.1//PREDICTED: DNA-directed RNA polymerases I, II, and III subunit RPABC5 [Rhinopithecus bieti]",4]
[9348,5961,0.51,0.71,0.477321777533186,0.212857337497109,"*",0.11521,"NDST3","GO:0016021//integral component of membrane","GO:0042328//heparan sulfate N-acetylglucosaminyltransferase activity;GO:0016787//hydrolase activity;GO:0015016//[heparan sulfate]-glucosamine N-sulfotransferase activity","GO:0015014//heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process","K02578//heparan sulfate N-deacetylase/N-sulfotransferase NDST3 [EC:3.1.1.- 2.8.2.-]","XP_012500826.1//PREDICTED: bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 [Propithecus coquereli]","2//1"]
[10423,1925,67.17,93.51,0.477303626772771,{"v":2.88089042051282e-23,"d":"2.88E-23"},"*",{"v":1.125376e-24,"d":"1.13E-24"},"CDIPT","GO:0016020//membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0000139//Golgi membrane","GO:0030246//carbohydrate binding;GO:0003881//CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity;GO:0019992//diacylglycerol binding;GO:0043178//alcohol binding;GO:0030145//manganese ion binding","GO:0046341//CDP-diacylglycerol metabolic process;GO:0006661//phosphatidylinositol biosynthetic process","K00999//CDP-diacylglycerol--inositol 3-phosphatidyltransferase [EC:2.7.8.11]","NP_006310.1//CDP-diacylglycerol--inositol 3-phosphatidyltransferase isoform 1 [Homo sapiens];ELW66369.1//CDP-diacylglycerol--inositol 3-phosphatidyltransferase [Tupaia chinensis]","1//3;4"]
[22913,4788,36.85,51.29,0.477012951994886,{"v":6.69180441481481e-32,"d":"6.69E-32"},"*",{"v":1.69662E-33,"d":"1.70E-33"},"RALY","GO:0005634//nucleus;GO:0071013//catalytic step 2 spliceosome","GO:0003723//RNA binding;GO:0003712//transcription cofactor activity","GO:1903506//regulation of nucleic acid-templated transcription;GO:0000398//mRNA splicing, via spliceosome;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:2000188//regulation of cholesterol homeostasis","K12895//heterogeneous nuclear ribonucleoprotein C-like 2","NP_031393.2//RNA-binding protein Raly isoform 2 [Homo sapiens];NP_057951.1//RNA-binding protein Raly isoform 1 [Homo sapiens]","3//A2MP1;2//1"]
[84922,2679,18.4,25.6,0.476438043942987,{"v":1.93183841163793e-09,"d":"1.93E-09"},"*",{"v":2.24458E-10,"d":"2.24E-10"},"FIZ1","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_011909026.1//PREDICTED: flt3-interacting zinc finger protein 1 isoform X3 [Cercocebus atys]","2//1"]
[150684,731,26.55,36.92,0.475690691954258,0.000525418638787592,"*",0.0001389034,"COMMD1","GO:0070062//extracellular exosome;GO:0010008//endosome membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0031462//Cul2-RING ubiquitin ligase complex;GO:0005829//cytosol;GO:0055037//recycling endosome;GO:0005769//early endosome","GO:0042802//identical protein binding;GO:0070300//phosphatidic acid binding;GO:0042803//protein homodimerization activity;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0080025//phosphatidylinositol-3,5-bisphosphate binding;GO:0005507//copper ion binding;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding","GO:0043687//post-translational protein modification;GO:2000009//negative regulation of protein localization to cell surface;GO:0055070//copper ion homeostasis;GO:0032434//regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0031398//positive regulation of protein ubiquitination;GO:0006351//transcription, DNA-templated;GO:0006893//Golgi to plasma membrane transport;GO:1902306//negative regulation of sodium ion transmembrane transport;GO:0015031//protein transport;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0048227//plasma membrane to endosome transport","NA","NP_689729.1//COMM domain-containing protein 1 isoform 1 [Homo sapiens];XP_004029343.2//PREDICTED: COMM domain-containing protein 1 [Gorilla gorilla gorilla];XP_015289094.1//PREDICTED: COMM domain-containing protein 1 isoform X2 [Macaca fascicularis]","1//3;3//A2MP1"]
[11045,1284,1.46,2.03,0.475511358305159,0.432098966887417,"*",0.28592,"UPK1A","GO:0070062//extracellular exosome;GO:0005783//endoplasmic reticulum;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0016324//apical plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0042803//protein homodimerization activity","GO:0007166//cell surface receptor signaling pathway;GO:0051259//protein oligomerization;GO:0030855//epithelial cell differentiation","K17347//uroplakin-1","NP_008931.1//uroplakin-1a isoform 1 [Homo sapiens];NP_001268372.1//uroplakin-1a isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[55876,1642,3.39,4.71,0.474441786476439,0.0772869986341463,"*",0.0347148,"GSDMB","GO:0005829//cytosol;GO:0005886//plasma membrane","NA","GO:0012501//programmed cell death","K22142//gasdermin-B","NP_061000.2//gasdermin-B isoform 2 [Homo sapiens];NP_001159430.1//gasdermin-B isoform 3 [Homo sapiens];NP_001035936.1//gasdermin-B isoform 1 [Homo sapiens];NP_001159431.1//gasdermin-B isoform 4 [Homo sapiens]","1//3;2//1"]
[1564,2371,0.36,0.5,0.473931188332412,0.578732459647615,"*",0.421532,"CYP2D7","NA","GO:0020037//heme binding;GO:0005506//iron ion binding;GO:0070330//aromatase activity","NA","K17712//cytochrome P450 family 2 subfamily D polypeptide 6 [EC:1.14.14.1]","A0A087X1C5.1//PUTATIVE PSEUDOGENE: RecName: Full=Putative cytochrome P450 2D7","1//3"]
[29984,1150,10.6,14.72,0.473713406606451,0.00601220435379337,"*",0.00197446,"RHOD","GO:0016020//membrane;GO:0010008//endosome membrane;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005886//plasma membrane;GO:0005769//early endosome","GO:0005525//GTP binding;GO:0019901//protein kinase binding;GO:0003924//GTPase activity","GO:0006605//protein targeting;GO:0030032//lamellipodium assembly;GO:0030335//positive regulation of cell migration;GO:0045785//positive regulation of cell adhesion;GO:2000249//regulation of actin cytoskeleton reorganization;GO:0051893//regulation of focal adhesion assembly;GO:0007266//Rho protein signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0051017//actin filament bundle assembly;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0048041//focal adhesion assembly","K07530//Ras homolog gene family, member D","NP_001287815.1//rho-related GTP-binding protein RhoD isoform 2 [Homo sapiens];NP_055393.1//rho-related GTP-binding protein RhoD isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[9945,3115,10.45,14.51,0.4735445770985,{"v":1.72758868171886E-6,"d":"1.73E-06"},"*",{"v":2.9698E-7,"d":"2.97E-07"},"GFPT2","GO:0005829//cytosol","GO:0097367//carbohydrate derivative binding;GO:0004360//glutamine-fructose-6-phosphate transaminase (isomerizing) activity","GO:0006047//UDP-N-acetylglucosamine metabolic process;GO:1901137//carbohydrate derivative biosynthetic process;GO:0006541//glutamine metabolic process;GO:1990830//cellular response to leukemia inhibitory factor;GO:0006002//fructose 6-phosphate metabolic process;GO:0006112//energy reserve metabolic process;GO:0006487//protein N-linked glycosylation;GO:0006048//UDP-N-acetylglucosamine biosynthetic process","K00820//glucosamine---fructose-6-phosphate aminotransferase (isomerizing) [EC:2.6.1.16]","XP_017372785.1//PREDICTED: glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 [Cebus capucinus imitator]","3//A2MP1"]
[6385,2615,20.27,28.14,0.473276239769634,{"v":6.03656822133485e-10,"d":"6.04E-10"},"*",{"v":6.62458e-11,"d":"6.62E-11"},"SDC4","GO:0070062//extracellular exosome;GO:0005925//focal adhesion;GO:0043034//costamere;GO:0005796//Golgi lumen;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0045121//membrane raft;GO:0016021//integral component of membrane;GO:0043202//lysosomal lumen;GO:0005886//plasma membrane","GO:0005080//protein kinase C binding;GO:0042802//identical protein binding;GO:0001968//fibronectin binding;GO:0070053//thrombospondin receptor activity","GO:1903543//positive regulation of exosomal secretion;GO:0016477//cell migration;GO:0010762//regulation of fibroblast migration;GO:0006024//glycosaminoglycan biosynthetic process;GO:0042130//negative regulation of T cell proliferation;GO:0045860//positive regulation of protein kinase activity;GO:0006027//glycosaminoglycan catabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0050900//leukocyte migration;GO:0051894//positive regulation of focal adhesion assembly;GO:0042060//wound healing;GO:0060122//inner ear receptor cell stereocilium organization;GO:0051496//positive regulation of stress fiber assembly;GO:0001523//retinoid metabolic process;GO:0001843//neural tube closure;GO:0001657//ureteric bud development;GO:1903553//positive regulation of extracellular exosome assembly","K16338//syndecan 4","NP_002990.2//syndecan-4 precursor [Homo sapiens]","3//A2MP1"]
[549,1598,3.4,4.72,0.473252113224139,0.102001281967651,"*",0.0477696,"AUH","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0004490//methylglutaconyl-CoA hydratase activity;GO:0003730//mRNA 3'-UTR binding;GO:0004300//enoyl-CoA hydratase activity","GO:0006635//fatty acid beta-oxidation;GO:0009083//branched-chain amino acid catabolic process;GO:0008152//metabolic process;GO:0006552//leucine catabolic process","K05607//methylglutaconyl-CoA hydratase [EC:4.2.1.18]","NP_001689.1//methylglutaconyl-CoA hydratase, mitochondrial isoform 1 precursor [Homo sapiens];NP_001293119.1//methylglutaconyl-CoA hydratase, mitochondrial isoform 2 [Homo sapiens];XP_005252123.1//PREDICTED: methylglutaconyl-CoA hydratase, mitochondrial isoform X1 [Homo sapiens];XP_016870338.1//PREDICTED: methylglutaconyl-CoA hydratase, mitochondrial isoform X3 [Homo sapiens]","1//3;2//1"]
[26648,1020,18.97,26.33,0.472987842634587,0.000420847971987443,"*",1.09098E-4,"OR7E24","NA","NA","NA","K04257//olfactory receptor","XP_010387160.1//PREDICTED: olfactory receptor 7E24 [Rhinopithecus roxellana]","1//3"]
[27344,1071,39.47,54.78,0.472892746812275,{"v":6.45898373901465e-08,"d":"6.46E-08"},"*",{"v":9.10986e-09,"d":"9.11E-09"},"PCSK1N","GO:0070062//extracellular exosome;GO:0030141//secretory granule;GO:0005615//extracellular space;GO:0005802//trans-Golgi network","GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005102//receptor binding;GO:0004866//endopeptidase inhibitor activity","GO:0016486//peptide hormone processing;GO:0009409//response to cold;GO:0002021//response to dietary excess;GO:0007218//neuropeptide signaling pathway","K03129//transcription initiation factor TFIID subunit 4;K15176//RNA polymerase-associated protein CTR9;K17498//transcription factor SPN1","NP_037403.1//proSAAS preproprotein [Homo sapiens]",4]
[349565,2128,0.49,0.68,0.472752997135131,0.529517010809853,"*",0.374116,"NMNAT3","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0000309//nicotinamide-nucleotide adenylyltransferase activity;GO:0005524//ATP binding;GO:0016779//nucleotidyltransferase activity;GO:0004515//nicotinate-nucleotide adenylyltransferase activity","GO:0009611//response to wounding;GO:0034628//'de novo' NAD biosynthetic process from aspartate;GO:0009058//biosynthetic process;GO:0019674//NAD metabolic process;GO:0009435//NAD biosynthetic process","K06210//nicotinamide mononucleotide adenylyltransferase [EC:2.7.7.1 2.7.7.18]","XP_008007113.1//PREDICTED: nicotinamide mononucleotide adenylyltransferase 3 isoform X3 [Chlorocebus sabaeus];NP_001307439.1//nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 isoform 3 [Homo sapiens];NP_001307440.1//nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 isoform 4 [Homo sapiens]","4;1//3;2//1"]
[4830,818,481.16,667.73,0.472748146824813,{"v":7.98108446709677e-65,"d":"7.98E-65"},"*",{"v":7.74426e-67,"d":"7.74E-67"},"NME1","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0043209//myelin sheath;GO:0005813//centrosome;GO:0032587//ruffle membrane;GO:0005741//mitochondrial outer membrane;GO:0005882//intermediate filament;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0005829//cytosol","GO:0000287//magnesium ion binding;GO:0003723//RNA binding;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0004536//deoxyribonuclease activity;GO:0043024//ribosomal small subunit binding;GO:0019215//intermediate filament binding;GO:0004550//nucleoside diphosphate kinase activity;GO:0019901//protein kinase binding;GO:0003697//single-stranded DNA binding;GO:0043015//gamma-tubulin binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0005525//GTP binding","GO:0007595//lactation;GO:0035690//cellular response to drug;GO:0021766//hippocampus development;GO:0002762//negative regulation of myeloid leukocyte differentiation;GO:0010629//negative regulation of gene expression;GO:0015949//nucleobase-containing small molecule interconversion;GO:0071398//cellular response to fatty acid;GO:0033574//response to testosterone;GO:0006897//endocytosis;GO:0043388//positive regulation of DNA binding;GO:0008285//negative regulation of cell proliferation;GO:0014075//response to amine;GO:0006241//CTP biosynthetic process;GO:0051591//response to cAMP;GO:0010976//positive regulation of neuron projection development;GO:0006228//UTP biosynthetic process;GO:0071333//cellular response to glucose stimulus;GO:0042981//regulation of apoptotic process;GO:0006183//GTP biosynthetic process;GO:0050679//positive regulation of epithelial cell proliferation","K00940//nucleoside-diphosphate kinase [EC:2.7.4.6]","NP_937818.1//nucleoside diphosphate kinase A isoform a [Homo sapiens];CAA35621.1//Nm23 protein, partial [Homo sapiens]","1//3;2//1"]
[51526,2260,16.79,23.3,0.472727724604613,{"v":2.36150948552523e-07,"d":"2.36E-07"},"*",{"v":3.57464e-08,"d":"3.57E-08"},"OSER1","NA","NA","NA","NA","XP_011784404.1//PREDICTED: oxidative stress-responsive serine-rich protein 1 isoform X1 [Colobus angolensis palliatus]",7]
[8527,6294,21.57,29.93,0.472566102337647,{"v":2.22356539099678E-23,"d":"2.22E-23"},"*",{"v":8.65818e-25,"d":"8.66E-25"},"DGKD","GO:0005634//nucleus;GO:0005829//cytosol;GO:0031410//cytoplasmic vesicle;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0004143//diacylglycerol kinase activity;GO:0003951//NAD+ kinase activity;GO:0046872//metal ion binding;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity;GO:0019992//diacylglycerol binding;GO:0042803//protein homodimerization activity","GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0007165//signal transduction;GO:0035556//intracellular signal transduction;GO:0051260//protein homooligomerization;GO:0030168//platelet activation;GO:0016049//cell growth;GO:0019932//second-messenger-mediated signaling;GO:0010033//response to organic substance;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007275//multicellular organism development;GO:0006897//endocytosis;GO:0015031//protein transport;GO:0046339//diacylglycerol metabolic process;GO:0046834//lipid phosphorylation","K00901//diacylglycerol kinase (ATP) [EC:2.7.1.107]","NP_003639.2//diacylglycerol kinase delta isoform 1 [Homo sapiens];NP_690618.2//diacylglycerol kinase delta isoform 2 [Homo sapiens]","2//1"]
[51303,945,30.92,42.89,0.472100996710709,0.000143639115518148,"*",{"v":3.41878e-05,"d":"3.42E-05"},"FKBP11","GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005737//cytoplasm","GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005528//FK506 binding","GO:0061077//chaperone-mediated protein folding","K09576//FK506-binding protein 11 [EC:5.2.1.8]","NP_057678.1//peptidyl-prolyl cis-trans isomerase FKBP11 isoform 1 precursor [Homo sapiens];XP_011791609.1//PREDICTED: peptidyl-prolyl cis-trans isomerase FKBP11 isoform X2 [Colobus angolensis palliatus];NP_001137254.1//peptidyl-prolyl cis-trans isomerase FKBP11 isoform 3 precursor [Homo sapiens]","1//3;2//1"]
[93343,1443,21.06,29.21,0.471956921803462,{"v":3.4134842004102e-05,"d":"3.41E-05"},"*",{"v":7.29324e-06,"d":"7.29E-06"},"MVB12A","GO:0043657//host cell;GO:0070062//extracellular exosome;GO:0010008//endosome membrane;GO:0005654//nucleoplasm;GO:0031902//late endosome membrane;GO:0000813//ESCRT I complex;GO:0005813//centrosome;GO:0031982//vesicle;GO:0005829//cytosol;GO:0005794//Golgi apparatus","GO:0008289//lipid binding;GO:0043130//ubiquitin binding;GO:0017124//SH3 domain binding","GO:0016197//endosomal transport;GO:0019075//virus maturation;GO:0048524//positive regulation of viral process;GO:0019058//viral life cycle;GO:0039702//viral budding via host ESCRT complex;GO:0036258//multivesicular body assembly;GO:1903772//regulation of viral budding via host ESCRT complex;GO:0042058//regulation of epidermal growth factor receptor signaling pathway;GO:0075733//intracellular transport of virus;GO:0015031//protein transport;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0016236//macroautophagy","K12186//ESCRT-I complex subunit MVB12","XP_002828938.1//PREDICTED: multivesicular body subunit 12A [Pongo abelii];XP_011781145.1//PREDICTED: multivesicular body subunit 12A isoform X2 [Colobus angolensis palliatus]","1//3;3//A2MP1"]
[7461,5461,9.82,13.62,0.471931773697378,{"v":3.60157823868313e-10,"d":"3.60E-10"},"*",{"v":3.83516e-11,"d":"3.84E-11"},"CLIP2","GO:0005875//microtubule associated complex;GO:0035371//microtubule plus-end;GO:0005881//cytoplasmic microtubule","GO:0051010//microtubule plus-end binding;GO:0008017//microtubule binding","NA","K10422//CAP-Gly domain-containing linker protein 2","NP_003379.3//CAP-Gly domain-containing linker protein 2 isoform 1 [Homo sapiens];NP_115797.1//CAP-Gly domain-containing linker protein 2 isoform 2 [Homo sapiens]","4;2//1"]
[222166,5814,1.06,1.47,0.471751890273165,0.0620631888537777,"*",0.0270492,"MTURN","NA","NA","NA","K10582//ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]","XP_007979925.1//PREDICTED: maturin [Chlorocebus sabaeus]","2//1"]
[388963,2142,3.83,5.31,0.471367468879196,0.0339260962332398,"*",0.01362226,"C2orf81","NA","NA","NA","K22020//mucin-19;K13172//serine/arginine repetitive matrix protein 2;K17501//protein phosphatase 1E [EC:3.1.3.16];K05626//atrophin-1 (dentatorubral-pallidoluysian atrophy protein);K19720//collagen, type III, alpha","NP_001138526.1//uncharacterized protein C2orf81 isoform 4 [Homo sapiens];NP_001303693.1//uncharacterized protein C2orf81 isoform 1 [Homo sapiens];NP_001303694.1//uncharacterized protein C2orf81 isoform 2 [Homo sapiens]","1//3"]
[386724,3008,2.33,3.23,0.471204210039645,0.0439907544411058,"*",0.01832994,"AMIGO3","GO:0016021//integral component of membrane","NA","GO:0051965//positive regulation of synapse assembly;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules","K10730//ATP-dependent DNA helicase Q4 [EC:3.6.4.12];K12169//Kip1 ubiquitination-promoting complex protein 1 [EC:2.3.2.27]","NP_942015.1//amphoterin-induced protein 3 precursor [Homo sapiens]","2//1"]
[118813,2761,11.65,16.15,0.471204210039644,{"v":1.508374782172e-05,"d":"1.51E-05"},"*",{"v":3.00844e-06,"d":"3.01E-06"},"ZFYVE27","GO:0032584//growth cone membrane;GO:0071782//endoplasmic reticulum tubular network;GO:0030425//dendrite;GO:0030424//axon;GO:0055038//recycling endosome membrane;GO:0005783//endoplasmic reticulum;GO:0030176//integral component of endoplasmic reticulum membrane","GO:0046872//metal ion binding;GO:0043621//protein self-association","GO:0045773//positive regulation of axon extension;GO:0072659//protein localization to plasma membrane;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0071787//endoplasmic reticulum tubular network formation;GO:0031175//neuron projection development;GO:0016192//vesicle-mediated transport","K19368//protrudin","XP_005269562.1//PREDICTED: protrudin isoform X3 [Homo sapiens];EAW49902.1//zinc finger, FYVE domain containing 27, isoform CRA_h [Homo sapiens];XP_007961961.1//PREDICTED: protrudin isoform X7 [Chlorocebus sabaeus];NP_001002261.1//protrudin isoform a [Homo sapiens];NP_653189.3//protrudin isoform b [Homo sapiens]","6;1//3;3//A2MP1"]
[100128242,1004,1.89,2.62,0.471180577316378,0.365151389905937,"*",0.226008,"LOC100128242","NA","NA","NA","K13172//serine/arginine repetitive matrix protein 2","XP_012351215.1//PREDICTED: uncharacterized protein LOC105737566 [Nomascus leucogenys]","1//3"]
[840,2415,7.88,10.92,0.470705321463476,0.00211382679219962,"*",0.000631078,"CASP7","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0097153//cysteine-type endopeptidase activity involved in apoptotic process;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0004197//cysteine-type endopeptidase activity;GO:0004190//aspartic-type endopeptidase activity;GO:0097200//cysteine-type endopeptidase activity involved in execution phase of apoptosis","GO:0051402//neuron apoptotic process;GO:0009411//response to UV;GO:0007507//heart development;GO:0007568//aging;GO:0006915//apoptotic process;GO:0097194//execution phase of apoptosis;GO:0006508//proteolysis;GO:0016485//protein processing;GO:0008635//activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c;GO:0072734//cellular response to staurosporine","K04397//caspase 7 [EC:3.4.22.60]","XP_007962308.1//PREDICTED: caspase-7 isoform X1 [Chlorocebus sabaeus];XP_001148847.3//PREDICTED: caspase-7 isoform X7 [Pan troglodytes];NP_203124.1//caspase-7 isoform delta [Homo sapiens];NP_001253986.1//caspase-7 isoform e [Homo sapiens];NP_203126.1//caspase-7 isoform beta [Homo sapiens]","4;1//3;3//A2MP1;5"]
[57057,1824,0.13,0.18,0.46948528330122,0.810953076664331,"*",0.724446,"TBX20","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0001105//RNA polymerase II transcription coactivator activity;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0001102//RNA polymerase II activating transcription factor binding;GO:0003700//DNA binding transcription factor activity","GO:0003148//outflow tract septum morphogenesis;GO:0003344//pericardium morphogenesis;GO:0021524//visceral motor neuron differentiation;GO:0010991//negative regulation of SMAD protein complex assembly;GO:0003143//embryonic heart tube morphogenesis;GO:0001706//endoderm formation;GO:0060577//pulmonary vein morphogenesis;GO:0036306//embryonic heart tube elongation;GO:0003272//endocardial cushion formation;GO:0003279//cardiac septum development;GO:0003193//pulmonary valve formation;GO:0055008//cardiac muscle tissue morphogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0003203//endocardial cushion morphogenesis;GO:0035922//foramen ovale closure;GO:0003215//cardiac right ventricle morphogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0009953//dorsal/ventral pattern formation;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0006936//muscle contraction;GO:0048370//lateral mesoderm formation;GO:0006351//transcription, DNA-templated;GO:0001947//heart looping;GO:0003207//cardiac chamber formation;GO:0008015//blood circulation;GO:0001764//neuron migration;GO:0060413//atrial septum morphogenesis;GO:0003180//aortic valve morphogenesis;GO:0003175//tricuspid valve development;GO:0001569//branching involved in blood vessel morphogenesis","K10185//T-box protein 20","XP_014920543.1//PREDICTED: T-box transcription factor TBX20 [Acinonyx jubatus];NP_001071121.1//T-box transcription factor TBX20 isoform 1 [Homo sapiens]","1//3;2//1"]
[64080,1391,3.64,5.04,0.46948528330122,0.183356089513823,"*",0.0963268,"RBKS","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0019200//carbohydrate kinase activity;GO:0005524//ATP binding;GO:0004747//ribokinase activity","GO:0046835//carbohydrate phosphorylation;GO:0006098//pentose-phosphate shunt;GO:0019303//D-ribose catabolic process","K00852//ribokinase [EC:2.7.1.15]","NP_071411.1//ribokinase isoform 1 [Homo sapiens]","1//3;2//1"]
[280,2253,0.26,0.36,0.46948528330122,0.634316395348837,"*",0.4781,"AMY2B","GO:0070062//extracellular exosome","GO:0043169//cation binding;GO:0046872//metal ion binding;GO:0004556//alpha-amylase activity;GO:0103025//alpha-amylase activity (releasing maltohexaose)","GO:0007586//digestion;GO:0005975//carbohydrate metabolic process","K01176//alpha-amylase [EC:3.2.1.1]","NP_066188.1//alpha-amylase 2B precursor [Homo sapiens]",4]
[4602,3220,0.13,0.18,0.46948528330122,0.695373745711706,"*",0.578622,"MYB","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016363//nuclear matrix","GO:0003677//DNA binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0001135//transcription factor activity, RNA polymerase II transcription factor recruiting","GO:0060252//positive regulation of glial cell proliferation;GO:0000278//mitotic cell cycle;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0032967//positive regulation of collagen biosynthetic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:2000491//positive regulation of hepatic stellate cell activation;GO:0070301//cellular response to hydrogen peroxide;GO:0045892//negative regulation of transcription, DNA-templated;GO:0051571//positive regulation of histone H3-K4 methylation;GO:0043525//positive regulation of neuron apoptotic process;GO:0045624//positive regulation of T-helper cell differentiation;GO:0051574//positive regulation of histone H3-K9 methylation;GO:0001666//response to hypoxia;GO:0071300//cellular response to retinoic acid;GO:1904899//positive regulation of hepatic stellate cell proliferation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0071636//positive regulation of transforming growth factor beta production;GO:1902036//regulation of hematopoietic stem cell differentiation;GO:2000845//positive regulation of testosterone secretion","K09420//transcriptional activator Myb","NP_001155128.1//transcriptional activator Myb isoform 4 [Homo sapiens];NP_001155130.1//transcriptional activator Myb isoform 6 [Homo sapiens];NP_001155132.1//transcriptional activator Myb isoform 8 [Homo sapiens];NP_001155129.1//transcriptional activator Myb isoform 5 [Homo sapiens];NP_001123645.1//transcriptional activator Myb isoform 1 [Homo sapiens];CAE82649.1//v-myb myeloblastosis viral oncogene homologue (avian), partial [Homo sapiens]","1//3;3//A2MP1"]
[30818,2735,0.73,1.01,0.468386923871777,0.386065451168364,"*",0.242022,"KCNIP3","GO:0030425//dendrite;GO:0030424//axon;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0043679//axon terminus;GO:0032993//protein-DNA complex;GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex","GO:0005244//voltage-gated ion channel activity;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0015459//potassium channel regulator activity;GO:0005267//potassium channel activity;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0044325//ion channel binding;GO:0005509//calcium ion binding","GO:0006886//intracellular protein transport;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0061337//cardiac conduction;GO:0007165//signal transduction;GO:0072659//protein localization to plasma membrane;GO:0006351//transcription, DNA-templated;GO:1901379//regulation of potassium ion transmembrane transport;GO:0006915//apoptotic process","K19932//neuronal calcium sensor 1;K16575//centractin","NP_038462.1//calsenilin isoform 1 [Homo sapiens];NP_001030086.1//calsenilin isoform 2 precursor [Homo sapiens]","4;1//3"]
[56654,1548,48.07,66.5,0.468217537138019,{"v":3.73687502560124e-13,"d":"3.74E-13"},"*",{"v":3.01542e-14,"d":"3.02E-14"},"NPDC1","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","NA","GO:0050776//regulation of immune response","K09367//POU domain transcription factor, class 5;K14676//lysophospholipid hydrolase [EC:3.1.1.5];K01509//adenosinetriphosphatase [EC:3.6.1.3]","NP_056207.3//neural proliferation differentiation and control protein 1 precursor [Homo sapiens]","3//A2MP1"]
[29085,1221,77.42,107.08,0.467910831348467,{"v":6.54247641233141e-16,"d":"6.54E-16"},"*",{"v":4.25134e-17,"d":"4.25E-17"},"PHPT1","GO:0070062//extracellular exosome;GO:0005829//cytosol","GO:0044325//ion channel binding;GO:0101006//protein histidine phosphatase activity;GO:0019855//calcium channel inhibitor activity;GO:0004721//phosphoprotein phosphatase activity","GO:2000984//negative regulation of ATP citrate synthase activity;GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:2000249//regulation of actin cytoskeleton reorganization;GO:0051350//negative regulation of lyase activity;GO:0050860//negative regulation of T cell receptor signaling pathway;GO:2000147//positive regulation of cell motility;GO:0006470//protein dephosphorylation;GO:0035971//peptidyl-histidine dephosphorylation","K01112//phosphohistidine phosphatase [EC:3.9.1.3]","NP_001129333.1//14 kDa phosphohistidine phosphatase isoform 2 [Homo sapiens];NP_001274272.1//14 kDa phosphohistidine phosphatase isoform 5 [Homo sapiens];XP_005580449.1//PREDICTED: 14 kDa phosphohistidine phosphatase isoform X6 [Macaca fascicularis]","1//3;2//1;5"]
[4733,1467,29.83,41.25,0.467630141685328,{"v":4.40727157674841e-08,"d":"4.41E-08"},"*",{"v":6.07538e-09,"d":"6.08E-09"},"DRG1","GO:0016020//membrane;GO:0016604//nuclear body;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005844//polysome","GO:0042802//identical protein binding;GO:0005525//GTP binding;GO:0008134//transcription factor binding","GO:0007275//multicellular organism development;GO:0006351//transcription, DNA-templated","K06944//uncharacterized protein","XP_015289556.1//PREDICTED: LOW QUALITY PROTEIN: developmentally-regulated GTP-binding protein 1-like [Macaca fascicularis]","3//A2MP1"]
[55132,2440,3.58,4.95,0.467468937702716,0.0835655993376569,"*",0.0379116,"LARP1B","GO:0005634//nucleus;GO:0030529//intracellular ribonucleoprotein complex;GO:0019013//viral nucleocapsid","GO:0003723//RNA binding","NA","K18757//la-related protein 1","XP_016863828.1//PREDICTED: la-related protein 1B isoform X5 [Homo sapiens];XP_011530366.2//PREDICTED: la-related protein 1B isoform X10 [Homo sapiens];XP_016863841.1//PREDICTED: la-related protein 1B isoform X27 [Homo sapiens];NP_115615.2//la-related protein 1B isoform 3 [Homo sapiens];XP_016863837.1//PREDICTED: la-related protein 1B isoform X23 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[79603,1817,3.46,4.78,0.466238580344024,0.0620721046976009,"*",0.0270492,"CERS4","GO:0005634//nucleus;GO:0031965//nuclear membrane;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0003677//DNA binding;GO:0050291//sphingosine N-acyltransferase activity","GO:0030148//sphingolipid biosynthetic process;GO:0046513//ceramide biosynthetic process","K04710//ceramide synthetase [EC:2.3.1.24]","NP_078828.2//ceramide synthase 4 [Homo sapiens]","2//1"]
[254427,3360,5.82,8.04,0.466176348270644,0.000359468976787463,"*",{"v":9.19038e-05,"d":"9.19E-05"},"PROSER2","NA","NA","NA","K16628//collagen, type VII, alpha;K22022//mucin-21","NP_694988.3//proline and serine-rich protein 2 [Homo sapiens]","3//A2MP1"]
[23640,1722,86.73,119.81,0.466145313747691,{"v":2.81855357205882e-25,"d":"2.82E-25"},"*",{"v":9.59868e-27,"d":"9.60E-27"},"HSPBP1","NA","GO:0004857//enzyme inhibitor activity","GO:0006457//protein folding;GO:0031398//positive regulation of protein ubiquitination;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process","K09562//hsp70-interacting protein","NP_001284529.1//hsp70-binding protein 1 isoform 1 [Homo sapiens]","4;1//3"]
[440822,3481,0.5,0.69,0.464668267003444,0.344849694341181,"*",0.20906,"PIWIL3","GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0003676//nucleic acid binding","GO:0030154//cell differentiation;GO:0007275//multicellular organism development;GO:0051321//meiotic cell cycle;GO:0031047//gene silencing by RNA;GO:0007283//spermatogenesis;GO:0006417//regulation of translation","K02156//aubergine","NP_001242904.1//piwi-like protein 3 isoform 2 [Homo sapiens];NP_001008496.2//piwi-like protein 3 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[1514,1630,362.42,499.83,0.463774923047926,{"v":5.02927295294118e-95,"d":"5.03E-95"},"*",{"v":3.21138e-97,"d":"3.21E-97"},"CTSL","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0043202//lysosomal lumen;GO:0005576//extracellular region;GO:0005764//lysosome;GO:0036021//endolysosome lumen","GO:0004252//serine-type endopeptidase activity;GO:0042393//histone binding;GO:0001968//fibronectin binding;GO:0043394//proteoglycan binding;GO:0097655//serpin family protein binding;GO:0005518//collagen binding;GO:0008234//cysteine-type peptidase activity;GO:0004197//cysteine-type endopeptidase activity","GO:0019882//antigen processing and presentation;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0071888//macrophage apoptotic process;GO:0002224//toll-like receptor signaling pathway;GO:0002250//adaptive immune response;GO:0022617//extracellular matrix disassembly;GO:0045616//regulation of keratinocyte differentiation;GO:0006508//proteolysis;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0097067//cellular response to thyroid hormone stimulus;GO:0030574//collagen catabolic process","K01365//cathepsin L [EC:3.4.22.15]","AAH12612.1//Cathepsin L1 [Homo sapiens];NP_001903.1//cathepsin L1 isoform 1 preproprotein [Homo sapiens]","4;1//3;2//1"]
[9296,749,266.16,367.01,0.463525601691093,{"v":3.50548829473684E-32,"d":"3.51E-32"},"*",{"v":8.75604e-34,"d":"8.76E-34"},"ATP6V1F","NA","NA","NA","K02151//V-type H+-transporting ATPase subunit F","XP_011794960.1//PREDICTED: V-type proton ATPase subunit F isoform X2 [Colobus angolensis palliatus];XP_011794959.1//PREDICTED: V-type proton ATPase subunit F isoform X1 [Colobus angolensis palliatus]","1//3;3//A2MP1"]
[7593,2693,10.12,13.95,0.46305583202224,{"v":5.52860683333333e-05,"d":"5.53E-05"},"*",{"v":1.221042e-05,"d":"1.22E-05"},"MZF1","GO:0005634//nucleus","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0042803//protein homodimerization activity;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding","NA","K09228//KRAB domain-containing zinc finger protein;K09229//KRAB and SCAN domains-containing zinc finger protein","XP_006940776.1//PREDICTED: myeloid zinc finger 1 isoform X4 [Felis catus]","1//3;2//1"]
[4794,2581,3.12,4.3,0.462790630727212,0.0339313864400437,"*",0.01362226,"NFKBIE","GO:0005634//nucleus;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0001650//fibrillar center;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm","NA","GO:0042994//cytoplasmic sequestering of transcription factor;GO:0042942//D-serine transport","K05872//NF-kappa-B inhibitor epsilon","NP_004547.2//NF-kappa-B inhibitor epsilon [Homo sapiens]","2//1"]
[8740,4406,0.82,1.13,0.462626957797104,0.187968364325477,"*",0.09935,"TNFSF14","GO:0005615//extracellular space;GO:0005622//intracellular;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0005164//tumor necrosis factor receptor binding;GO:0005125//cytokine activity;GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process;GO:0042802//identical protein binding;GO:0005102//receptor binding","GO:0042110//T cell activation;GO:0010820//positive regulation of T cell chemotaxis;GO:0007165//signal transduction;GO:0071260//cellular response to mechanical stimulus;GO:0008588//release of cytoplasmic sequestered NF-kappaB;GO:0031295//T cell costimulation;GO:0006915//apoptotic process;GO:0043029//T cell homeostasis;GO:0042098//T cell proliferation;GO:0006955//immune response;GO:0045663//positive regulation of myoblast differentiation;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:1901741//positive regulation of myoblast fusion","K05477//tumor necrosis factor ligand superfamily member 14","NP_742011.2//tumor necrosis factor ligand superfamily member 14 isoform 2 [Homo sapiens];NP_003798.2//tumor necrosis factor ligand superfamily member 14 isoform 1 [Homo sapiens]","4;3//A2MP1"]
[2627,3785,0.9,1.24,0.4623432140572,0.208336602161534,"*",0.1122284,"GATA6","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0005667//transcription factor complex","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0001103//RNA polymerase II repressing transcription factor binding;GO:0044212//transcription regulatory region DNA binding;GO:0003705//transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0019901//protein kinase binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0008270//zinc ion binding;GO:0008134//transcription factor binding;GO:0003700//DNA binding transcription factor activity","GO:0003148//outflow tract septum morphogenesis;GO:0007596//blood coagulation;GO:0030513//positive regulation of BMP signaling pathway;GO:0043627//response to estrogen;GO:0051891//positive regulation of cardioblast differentiation;GO:0032912//negative regulation of transforming growth factor beta2 production;GO:0003309//type B pancreatic cell differentiation;GO:0008584//male gonad development;GO:0044267//cellular protein metabolic process;GO:0032911//negative regulation of transforming growth factor beta1 production;GO:0045766//positive regulation of angiogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0060486//Clara cell differentiation;GO:0042493//response to drug;GO:0055007//cardiac muscle cell differentiation;GO:0110024//positive regulation of cardiac muscle myoblast proliferation;GO:0043066//negative regulation of apoptotic process;GO:0060575//intestinal epithelial cell differentiation;GO:0070848//response to growth factor;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0071773//cellular response to BMP stimulus;GO:0071456//cellular response to hypoxia;GO:0014898//cardiac muscle hypertrophy in response to stress;GO:0035239//tube morphogenesis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0071371//cellular response to gonadotropin stimulus;GO:0060510//Type II pneumocyte differentiation;GO:0048645//animal organ formation;GO:0007493//endodermal cell fate determination;GO:0060430//lung saccule development;GO:0001889//liver development;GO:0003310//pancreatic A cell differentiation;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0060947//cardiac vascular smooth muscle cell differentiation;GO:0001701//in utero embryonic development;GO:0006366//transcription from RNA polymerase II promoter;GO:0051145//smooth muscle cell differentiation;GO:0071158//positive regulation of cell cycle arrest;GO:0006644//phospholipid metabolic process","K17897//GATA-binding protein 6","NP_005248.2//transcription factor GATA-6 [Homo sapiens]",5]
[652968,1644,6.09,8.39,0.462228582533491,0.0161428015149957,"*",0.00589666,"CASTOR1","GO:0005829//cytosol;GO:0061700//GATOR2 complex","GO:0034618//arginine binding;GO:0042802//identical protein binding","GO:1903577//cellular response to L-arginine;GO:1903432//regulation of TORC1 signaling;GO:1904262//negative regulation of TORC1 signaling","K19944//TBC1 domain family member 10","XP_003317231.2//PREDICTED: GATS-like protein 3 isoform X2 [Pan troglodytes]","2//1"]
[10938,3438,36.99,50.94,0.461663659150199,{"v":5.03638588541667E-20,"d":"5.04E-20"},"*",{"v":2.4214e-21,"d":"2.42E-21"},"EHD1","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0010008//endosome membrane;GO:0043209//myelin sheath;GO:0048471//perinuclear region of cytoplasm;GO:0055038//recycling endosome membrane;GO:0031901//early endosome membrane;GO:0031095//platelet dense tubular network membrane;GO:0030139//endocytic vesicle;GO:0005811//lipid droplet;GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0020018//ciliary pocket membrane","GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0005509//calcium ion binding;GO:0005525//GTP binding;GO:0017137//Rab GTPase binding;GO:0045296//cadherin binding","GO:0016197//endosomal transport;GO:0034383//low-density lipoprotein particle clearance;GO:0007596//blood coagulation;GO:2001137//positive regulation of endocytic recycling;GO:0061512//protein localization to cilium;GO:0051260//protein homooligomerization;GO:1990090//cellular response to nerve growth factor stimulus;GO:0006886//intracellular protein transport;GO:0060271//cilium assembly;GO:0010886//positive regulation of cholesterol storage;GO:0031175//neuron projection development;GO:0042632//cholesterol homeostasis;GO:0006897//endocytosis;GO:0032456//endocytic recycling;GO:1901741//positive regulation of myoblast fusion","K12483//EH domain-containing protein 1","NP_001269374.1//EH domain-containing protein 1 isoform 2 [Homo sapiens];XP_010994338.1//PREDICTED: EH domain-containing protein 1 [Camelus dromedarius]","1//3;3//A2MP1"]
[57085,1187,48.18,66.35,0.461662072019085,{"v":2.25622892474413e-10,"d":"2.26E-10"},"*",{"v":2.34606E-11,"d":"2.35E-11"},"AGTRAP","GO:0043231//intracellular membrane-bounded organelle;GO:0005654//nucleoplasm;GO:0005938//cell cortex;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0000139//Golgi membrane;GO:0030659//cytoplasmic vesicle membrane","GO:0004945//angiotensin type II receptor activity","GO:0008217//regulation of blood pressure;GO:0038166//angiotensin-activated signaling pathway;GO:0001666//response to hypoxia","K14435//chromodomain-helicase-DNA-binding protein 5 [EC:3.6.4.12]","XP_011540101.2//PREDICTED: type-1 angiotensin II receptor-associated protein isoform X3 [Homo sapiens];NP_001035286.1//type-1 angiotensin II receptor-associated protein isoform d [Homo sapiens];NP_065083.3//type-1 angiotensin II receptor-associated protein isoform a [Homo sapiens];NP_001035284.1//type-1 angiotensin II receptor-associated protein isoform b [Homo sapiens]","1//3;4"]
[1258,5208,0.61,0.84,0.461580085215874,0.170566607967166,"*",0.0884546,"CNGB1","GO:0060170//ciliary membrane;GO:0043195//terminal bouton;GO:0001750//photoreceptor outer segment;GO:0017071//intracellular cyclic nucleotide activated cation channel complex;GO:0030660//Golgi-associated vesicle membrane;GO:0000139//Golgi membrane;GO:0005887//integral component of plasma membrane;GO:1902495//transmembrane transporter complex;GO:0005886//plasma membrane","GO:0015276//ligand-gated ion channel activity;GO:0030552//cAMP binding;GO:0005249//voltage-gated potassium channel activity;GO:0005223//intracellular cGMP activated cation channel activity;GO:0005222//intracellular cAMP activated cation channel activity;GO:0030553//cGMP binding","GO:0006810//transport;GO:0007608//sensory perception of smell;GO:0016056//rhodopsin mediated signaling pathway;GO:0035845//photoreceptor cell outer segment organization;GO:0050908//detection of light stimulus involved in visual perception;GO:0001895//retina homeostasis;GO:0007601//visual perception;GO:0006812//cation transport;GO:0051290//protein heterotetramerization;GO:0045494//photoreceptor cell maintenance;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0033365//protein localization to organelle;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0042391//regulation of membrane potential","K04952//cyclic nucleotide gated channel beta 1","NP_001129111.1//cyclic nucleotide-gated cation channel beta-1 isoform b [Homo sapiens];NP_001273059.1//cyclic nucleotide-gated cation channel beta-1 isoform c [Homo sapiens];NP_001288.3//cyclic nucleotide-gated cation channel beta-1 isoform a [Homo sapiens]","1//3;4"]
[780776,3439,1.91,2.63,0.461490161256553,0.0577112899593732,"*",0.0248996,"TVP23A","GO:0030173//integral component of Golgi membrane;GO:0016021//integral component of membrane","NA","GO:0009306//protein secretion;GO:0016192//vesicle-mediated transport","K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K01064//wingless-type MMTV integration site family, member 9","NP_001072980.1//Golgi apparatus membrane protein TVP23 homolog A isoform 1 [Homo sapiens];XP_011989660.2//PREDICTED: Golgi apparatus membrane protein TVP23 homolog A isoform X2 [Ovis aries musimon]","1//3;3//A2MP1"]
[103910,1005,217.13,298.98,0.461489908618367,{"v":4.263979755e-32,"d":"4.26E-32"},"*",{"v":1.06773E-33,"d":"1.07E-33"},"MYL12B","NA","NA","NA","K12757//myosin regulatory light chain 12","XP_004474453.1//PREDICTED: myosin regulatory light polypeptide 9 isoform X1 [Dasypus novemcinctus];ELK31627.1//Myosin regulatory light polypeptide 9 [Myotis davidii]","1//3;3//A2MP1"]
[8775,1865,110.1,151.52,0.460693767016654,{"v":6.98999910752688e-34,"d":"6.99E-34"},"*",{"v":1.62782e-35,"d":"1.63E-35"},"NAPA","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005622//intracellular;GO:0043209//myelin sheath;GO:0043195//terminal bouton;GO:0070044//synaptobrevin 2-SNAP-25-syntaxin-1a complex;GO:0000139//Golgi membrane;GO:0005774//vacuolar membrane;GO:0005829//cytosol;GO:0031201//SNARE complex;GO:0005886//plasma membrane","GO:0000149//SNARE binding;GO:0005483//soluble NSF attachment protein activity;GO:0019905//syntaxin binding;GO:0032403//protein complex binding","GO:0030182//neuron differentiation;GO:0035494//SNARE complex disassembly;GO:0048208//COPII vesicle coating;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0007420//brain development;GO:0045176//apical protein localization;GO:0006886//intracellular protein transport;GO:0061025//membrane fusion;GO:0032781//positive regulation of ATPase activity;GO:0035249//synaptic transmission, glutamatergic;GO:0010807//regulation of synaptic vesicle priming;GO:0006888//ER to Golgi vesicle-mediated transport","K15296//alpha-soluble NSF attachment protein","XP_012888195.1//PREDICTED: alpha-soluble NSF attachment protein [Dipodomys ordii]","3//A2MP1"]
[51267,2879,0.24,0.33,0.459431618637297,0.534814462728551,"*",0.380872,"CLEC1A","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005622//intracellular","GO:0030246//carbohydrate binding;GO:0004888//transmembrane signaling receptor activity","GO:0006952//defense response;GO:0007166//cell surface receptor signaling pathway","K10069//C-type lectin domain family 1 member A","NP_057595.2//C-type lectin domain family 1 member A isoform a [Homo sapiens];NP_001284677.1//C-type lectin domain family 1 member A isoform b [Homo sapiens];NP_001284678.1//C-type lectin domain family 1 member A isoform c [Homo sapiens];BAC11410.1//unnamed protein product [Homo sapiens];XP_018893321.1//PREDICTED: C-type lectin domain family 1 member A isoform X2 [Gorilla gorilla gorilla]","1//3;3//A2MP1"]
[79924,4045,0.88,1.21,0.459431618637297,0.219017366482505,"*",0.11912,"ADM2","NA","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K11447//histone demethylase [EC:1.14.11.-];K01064//wingless-type MMTV integration site family, member 9","CAG30365.1//dJ579N16.4 [Homo sapiens]","1//3"]
[23671,2816,0.08,0.11,0.459431618637297,0.811464862492111,"*",0.724446,"TMEFF2","GO:0016021//integral component of membrane;GO:0005576//extracellular region","NA","GO:0045720//negative regulation of integrin biosynthetic process;GO:0051497//negative regulation of stress fiber assembly;GO:0030336//negative regulation of cell migration;GO:0044319//wound healing, spreading of cells","K06254//agrin","XP_010387068.1//PREDICTED: tomoregulin-2 isoform X1 [Rhinopithecus roxellana];NP_001292074.1//tomoregulin-2 isoform 3 precursor [Homo sapiens]","1//3;3//A2MP1"]
[387032,5365,0.4,0.55,0.459431618637297,0.328987730133556,"*",0.1973844,"ZKSCAN4","NA","NA","NA","K09229//KRAB and SCAN domains-containing zinc finger protein","XP_007179164.1//PREDICTED: uncharacterized protein LOC102999167 [Balaenoptera acutorostrata scammoni];XP_012321245.1//zinc finger protein with KRAB and SCAN domains 4 isoform X1 [Aotus nancymaae]","1//3;4"]
[148979,2816,0.08,0.11,0.459431618637297,0.810839434136771,"*",0.724446,"GLIS1","GO:0005634//nucleus","GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding","GO:0006357//regulation of transcription from RNA polymerase II promoter","K09232//zinc finger protein GLIS1/3","XP_016855897.1//PREDICTED: zinc finger protein GLIS1 isoform X1 [Homo sapiens]","2//1"]
[9435,4154,0.08,0.11,0.459431618637297,0.665964246796827,"*",0.546646,"CHST2","GO:0005794//Golgi apparatus;GO:0031228//intrinsic component of Golgi membrane;GO:0016021//integral component of membrane;GO:0005802//trans-Golgi network;GO:0000139//Golgi membrane","GO:0008146//sulfotransferase activity;GO:0001517//N-acetylglucosamine 6-O-sulfotransferase activity","GO:0006790//sulfur compound metabolic process;GO:0018146//keratan sulfate biosynthetic process;GO:0006044//N-acetylglucosamine metabolic process;GO:0007275//multicellular organism development;GO:0005975//carbohydrate metabolic process;GO:0006954//inflammatory response","K04745//carbohydrate 6-sulfotransferase 2 [EC:2.8.2.-]","EDL77523.1//rCG25901 [Rattus norvegicus]",4]
[80031,5884,0.08,0.11,0.459431618637297,0.718621989731379,"*",0.60458,"SEMA6D","GO:0005887//integral component of plasma membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0030215//semaphorin receptor binding","GO:0014912//negative regulation of smooth muscle cell migration;GO:0030154//cell differentiation;GO:0021591//ventricular system development;GO:0014911//positive regulation of smooth muscle cell migration","K06842//semaphorin 6","NP_065909.1//semaphorin-6D isoform 1 precursor [Homo sapiens];XP_010597977.1//PREDICTED: LOW QUALITY PROTEIN: semaphorin-6D [Loxodonta africana];XP_014952552.1//PREDICTED: semaphorin-6D isoform X7 [Ovis aries];NP_705869.1//semaphorin-6D isoform 2 precursor [Homo sapiens];NP_705871.1//semaphorin-6D isoform 4 precursor [Homo sapiens];NP_705870.1//semaphorin-6D isoform 3 precursor [Homo sapiens];XP_005254742.1//PREDICTED: semaphorin-6D isoform X1 [Homo sapiens]","1//3;2//1"]
[55138,2516,0.32,0.44,0.459431618637297,0.658002113450203,"*",0.538092,"FAM90A1","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_018894904.1//PREDICTED: protein FAM90A1 isoform X2 [Gorilla gorilla gorilla]","1//3;3//A2MP1"]
[402415,2854,0.08,0.11,0.459431618637297,0.810498697576691,"*",0.724446,"XKRX","GO:0016021//integral component of membrane","NA","NA","K19522//membrane transport protein XK","XP_003940179.1//PREDICTED: XK-related protein 2 [Saimiri boliviensis boliviensis]","2//1"]
[794,1391,1.23,1.69,0.458364930942945,0.344742896665634,"*",0.20906,"CALB2","GO:0005634//nucleus;GO:0005921//gap junction;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0043195//terminal bouton;GO:0045202//synapse;GO:0043005//neuron projection","GO:0005509//calcium ion binding","GO:0051480//regulation of cytosolic calcium ion concentration","K14757//calbindin D28","NP_009019.1//calretinin isoform 22k [Homo sapiens];NP_001731.2//calretinin isoform 1 [Homo sapiens]","4;3//A2MP1"]
[64837,2801,45.52,62.54,0.458278661618458,{"v":7.74809408815427e-21,"d":"7.75E-21"},"*",{"v":3.52142e-22,"d":"3.52E-22"},"KLC2","GO:0016020//membrane;GO:0005874//microtubule;GO:0043234//protein complex;GO:0005829//cytosol;GO:0016938//kinesin I complex;GO:0005871//kinesin complex","GO:0003777//microtubule motor activity;GO:0019894//kinesin binding;GO:0045296//cadherin binding","GO:0007018//microtubule-based movement;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER","K10407//kinesin light chain","XP_011797838.1//PREDICTED: kinesin light chain 2 isoform X1 [Colobus angolensis palliatus];NP_073733.1//kinesin light chain 2 isoform 1 [Homo sapiens];NP_001128246.1//kinesin light chain 2 isoform 2 [Homo sapiens]","1//3;2//1"]
[64743,1945,31.74,43.6,0.458026006829107,{"v":8.23543959570436e-11,"d":"8.24E-11"},"*",{"v":8.1612e-12,"d":"8.16E-12"},"WDR13","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005815//microtubule organizing center;GO:0005886//plasma membrane","GO:1990841//promoter-specific chromatin binding","GO:1904691//negative regulation of type B pancreatic cell proliferation","K14963//COMPASS component SWD3","XP_012016279.1//PREDICTED: WD repeat-containing protein 13 isoform X2 [Ovis aries musimon];XP_021105636.1//WD repeat-containing protein 13 isoform X2 [Heterocephalus glaber];XP_016798097.1//PREDICTED: WD repeat-containing protein 13 isoform X2 [Pan troglodytes];XP_009195792.1//WD repeat-containing protein 13 isoform X1 [Papio anubis]","1//3;2//1;5"]
[151176,2911,2.41,3.31,0.457798070577256,0.0510993986162226,"*",0.0217302,"ERFE","GO:0005615//extracellular space;GO:0005623//cell;GO:0005576//extracellular region","GO:0042803//protein homodimerization activity;GO:0005179//hormone activity","GO:0019217//regulation of fatty acid metabolic process;GO:0006879//cellular iron ion homeostasis;GO:2000193//positive regulation of fatty acid transport","K21410//adipolin","NP_001278761.1//erythroferrone precursor [Homo sapiens]","1//3"]
[202915,6293,10.69,14.68,0.457590115122722,{"v":1.11554615253772e-11,"d":"1.12E-11"},"*",{"v":1.018196E-12,"d":"1.02E-12"},"TMEM184A","GO:0016021//integral component of membrane","NA","NA","K22020//mucin-19","XP_017824710.1//PREDICTED: transmembrane protein 184A [Callithrix jacchus]","1//3"]
[114757,2166,0.67,0.92,0.45747276559924,0.434429506792453,"*",0.288278,"CYGB","GO:0016607//nuclear speck;GO:0043025//neuronal cell body;GO:0043005//neuron projection","GO:0020037//heme binding;GO:0005506//iron ion binding;GO:0005344//oxygen carrier activity;GO:0019825//oxygen binding","NA","K21894//cytoglobin","EAW89405.1//cytoglobin, isoform CRA_a [Homo sapiens]",4]
[83658,716,216.24,296.86,0.457149295438882,{"v":1.64335596923077e-24,"d":"1.64E-24"},"*",{"v":5.88456e-26,"d":"5.88E-26"},"DYNLRB1","GO:0016020//membrane;GO:0005929//cilium;GO:0036157//outer dynein arm;GO:0005874//microtubule;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0097542//ciliary tip;GO:0005868//cytoplasmic dynein complex","GO:0045505//dynein intermediate chain binding;GO:0003774//motor activity;GO:0003777//microtubule motor activity","GO:0006810//transport;GO:0007018//microtubule-based movement;GO:0035735//intraciliary transport involved in cilium assembly;GO:0007632//visual behavior","K10419//dynein light chain roadblock-type","NP_001306086.1//dynein light chain roadblock-type 1 isoform d [Homo sapiens];EAW76268.1//hCG38498, isoform CRA_b [Homo sapiens];NP_001268658.1//dynein light chain roadblock-type 1 isoform c [Homo sapiens]","1//3;3//A2MP1;2//1"]
[79922,1851,13.17,18.08,0.457139332158673,{"v":9.51956152963671e-05,"d":"9.52E-05"},"*",{"v":2.18174e-05,"d":"2.18E-05"},"MRM1","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0003723//RNA binding;GO:0070039//rRNA (guanosine-2'-O-)-methyltransferase activity;GO:0008173//RNA methyltransferase activity","GO:0006396//RNA processing;GO:0000453//enzyme-directed rRNA 2'-O-methylation;GO:0000451//rRNA 2'-O-methylation","K15507//21S rRNA (GM2251-2'-O)-methyltransferase [EC:2.1.1.-]","XP_008009369.1//PREDICTED: rRNA methyltransferase 1, mitochondrial [Chlorocebus sabaeus]",4]
[4061,1192,180.28,247.49,0.457130878139993,{"v":2.99313372054795e-34,"d":"2.99E-34"},"*",{"v":6.8392e-36,"d":"6.84E-36"},"LY6E","GO:0005887//integral component of plasma membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0031225//anchored component of membrane","NA","GO:0006501//C-terminal protein lipidation;GO:0007166//cell surface receptor signaling pathway","K06846//lymphocyte antigen 6 complex locus protein D/E/G6/H","NP_002337.1//lymphocyte antigen 6E precursor [Homo sapiens]","1//3;2//1"]
[29937,995,51.5,70.69,0.456933709601638,{"v":9.16383576808722e-09,"d":"9.16E-09"},"*",{"v":1.15767E-9,"d":"1.16E-09"},"NENF","GO:0016020//membrane;GO:0012505//endomembrane system;GO:0005615//extracellular space","GO:0046872//metal ion binding;GO:0008083//growth factor activity","GO:0043410//positive regulation of MAPK cascade;GO:0032099//negative regulation of appetite","K17278//membrane-associated progesterone receptor component","NP_037481.1//neudesin precursor [Homo sapiens]",4]
[9136,1590,32.58,44.72,0.456933584317672,{"v":5.37410883034341e-09,"d":"5.37E-09"},"*",{"v":6.56372E-10,"d":"6.56E-10"},"RRP9","GO:0005654//nucleoplasm;GO:0032040//small-subunit processome;GO:0005730//nucleolus;GO:0031428//box C/D snoRNP complex","GO:0030515//snoRNA binding;GO:0034511//U3 snoRNA binding;GO:0003723//RNA binding","GO:0006364//rRNA processing","K14793//ribosomal RNA-processing protein 9","NP_004695.1//U3 small nucleolar RNA-interacting protein 2 [Homo sapiens]",4]
[2015,2630,3.25,4.46,0.456603992004488,0.0294265678841871,"*",0.01157978,"ADGRE1","GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016021//integral component of membrane","GO:0005509//calcium ion binding;GO:0004930//G-protein coupled receptor activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0007155//cell adhesion;GO:0007166//cell surface receptor signaling pathway;GO:0002250//adaptive immune response","K04591//egf-like module containing, mucin-like, hormone receptor-like 1","NP_001243182.1//adhesion G protein-coupled receptor E1 isoform 3 precursor [Homo sapiens];NP_001965.3//adhesion G protein-coupled receptor E1 isoform 1 precursor [Homo sapiens];NP_001243184.1//adhesion G protein-coupled receptor E1 isoform 5 precursor [Homo sapiens];NP_001243181.1//adhesion G protein-coupled receptor E1 isoform 2 precursor [Homo sapiens];NP_001243183.1//adhesion G protein-coupled receptor E1 isoform 4 precursor [Homo sapiens]","4;1//3"]
[7311,2840,95.63,131.17,0.455902616829982,{"v":4.84867696444444e-43,"d":"4.85E-43"},"*",{"v":8.19546e-45,"d":"8.20E-45"},"UBA52","NA","NA","NA","K08770//ubiquitin C;K02927//large subunit ribosomal protein L40e","XP_016882687.1//PREDICTED: ubiquitin-60S ribosomal protein L40 isoform X1 [Homo sapiens];NP_001307950.1//ubiquitin-60S ribosomal protein L40 isoform 2 [Homo sapiens];XP_003277840.2//PREDICTED: ubiquitin-60S ribosomal protein L40-like isoform X1 [Nomascus leucogenys];EPY79925.1//ubiquitin A-52 residue ribosomal protein fusion product 1-like protein [Camelus ferus];XP_004060373.2//PREDICTED: ubiquitin-60S ribosomal protein L40 isoform X3 [Gorilla gorilla gorilla]","4;1//3;2//1"]
[3400,3891,2.96,4.06,0.455882551556226,0.00981265799237611,"*",3.38412E-3,"ID4","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0001085//RNA polymerase II transcription factor binding;GO:0046983//protein dimerization activity","GO:0048712//negative regulation of astrocyte differentiation;GO:0021766//hippocampus development;GO:0022010//central nervous system myelination;GO:0061682//seminal vesicle morphogenesis;GO:0060740//prostate gland epithelium morphogenesis;GO:0007405//neuroblast proliferation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007623//circadian rhythm;GO:0045892//negative regulation of transcription, DNA-templated;GO:0021895//cerebral cortex neuron differentiation;GO:0006351//transcription, DNA-templated;GO:0060741//prostate gland stromal morphogenesis;GO:0045599//negative regulation of fat cell differentiation;GO:0048715//negative regulation of oligodendrocyte differentiation;GO:0045669//positive regulation of osteoblast differentiation;GO:0045665//negative regulation of neuron differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045444//fat cell differentiation;GO:0000082//G1/S transition of mitotic cell cycle;GO:0034613//cellular protein localization;GO:0008284//positive regulation of cell proliferation","K17695//DNA-binding protein inhibitor ID4","NP_001537.1//DNA-binding protein inhibitor ID-4 [Homo sapiens]","3//A2MP1"]
[1535,778,247.53,339.42,0.45546819009452,{"v":6.2721492546697e-30,"d":"6.27E-30"},"*",{"v":1.723722e-31,"d":"1.72E-31"},"CYBA","GO:0016020//membrane;GO:0030425//dendrite;GO:0097038//perinuclear endoplasmic reticulum;GO:0016324//apical plasma membrane;GO:0043025//neuronal cell body;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0070821//tertiary granule membrane;GO:0005886//plasma membrane;GO:0005634//nucleus;GO:0005925//focal adhesion;GO:0030670//phagocytic vesicle membrane;GO:0005768//endosome;GO:0030141//secretory granule;GO:0001725//stress fiber;GO:0005794//Golgi apparatus;GO:0043020//NADPH oxidase complex;GO:0035579//specific granule membrane;GO:0005789//endoplasmic reticulum membrane","GO:0009055//electron transfer activity;GO:0046872//metal ion binding;GO:0020037//heme binding;GO:0046982//protein heterodimerization activity;GO:0017124//SH3 domain binding;GO:0016175//superoxide-generating NADPH oxidase activity","GO:0006801//superoxide metabolic process;GO:0032930//positive regulation of superoxide anion generation;GO:0071260//cellular response to mechanical stimulus;GO:1903428//positive regulation of reactive oxygen species biosynthetic process;GO:1904385//cellular response to angiotensin;GO:0017004//cytochrome complex assembly;GO:1900426//positive regulation of defense response to bacterium;GO:0071356//cellular response to tumor necrosis factor;GO:1904044//response to aldosterone;GO:0045454//cell redox homeostasis;GO:0032760//positive regulation of tumor necrosis factor production;GO:0070555//response to interleukin-1;GO:1904845//cellular response to L-glutamine;GO:0045087//innate immune response;GO:0042493//response to drug;GO:0001666//response to hypoxia;GO:0071333//cellular response to glucose stimulus;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0034599//cellular response to oxidative stress;GO:0032755//positive regulation of interleukin-6 production;GO:0070257//positive regulation of mucus secretion;GO:0051279//regulation of release of sequestered calcium ion into cytosol;GO:0030307//positive regulation of cell growth;GO:0033864//positive regulation of NAD(P)H oxidase activity;GO:0055114//oxidation-reduction process;GO:0050766//positive regulation of phagocytosis;GO:0071407//cellular response to organic cyclic compound;GO:0043312//neutrophil degranulation;GO:0042554//superoxide anion generation;GO:0001938//positive regulation of endothelial cell proliferation;GO:0034137//positive regulation of toll-like receptor 2 signaling pathway;GO:0014823//response to activity;GO:0071480//cellular response to gamma radiation;GO:0006954//inflammatory response;GO:0045730//respiratory burst;GO:0014895//smooth muscle hypertrophy;GO:0031667//response to nutrient levels;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0050665//hydrogen peroxide biosynthetic process;GO:0003106//negative regulation of glomerular filtration by angiotensin","K08009//cytochrome b-245, alpha polypeptide","NP_000092.2//cytochrome b-245 light chain [Homo sapiens]","3//A2MP1"]
[11066,998,8.69,11.91,0.454745331049714,0.020667633068616,"*",0.00778756,"SNRNP35","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005689//U12-type spliceosomal complex;GO:0071011//precatalytic spliceosome;GO:0000243//commitment complex","GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0017069//snRNA binding","GO:0000398//mRNA splicing, via spliceosome;GO:0008380//RNA splicing","K13155//U11/U12 small nuclear ribonucleoprotein 35 kDa protein","XP_011536082.1//PREDICTED: U11/U12 small nuclear ribonucleoprotein 35 kDa protein isoform X1 [Homo sapiens];NP_851030.1//U11/U12 small nuclear ribonucleoprotein 35 kDa protein isoform b [Homo sapiens]","3//A2MP1"]
[2766,1515,0.27,0.37,0.454565863465481,0.695583069536424,"*",0.578622,"GMPR","GO:1902560//GMP reductase complex;GO:0005829//cytosol","GO:0046872//metal ion binding;GO:0003920//GMP reductase activity","GO:0009409//response to cold;GO:0006144//purine nucleobase metabolic process;GO:0043101//purine-containing compound salvage;GO:0006163//purine nucleotide metabolic process;GO:0009117//nucleotide metabolic process","K00364//GMP reductase [EC:1.7.1.7]","NP_006868.3//GMP reductase 1 [Homo sapiens]","3//A2MP1"]
[9567,5074,5.27,7.22,0.454195875249957,{"v":3.97212737962963e-05,"d":"3.97E-05"},"*",{"v":8.59376e-06,"d":"8.59E-06"},"GTPBP1","GO:0016020//membrane;GO:0005829//cytosol;GO:0000177//cytoplasmic exosome (RNase complex)","GO:0003723//RNA binding;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0007165//signal transduction;GO:0061014//positive regulation of mRNA catabolic process;GO:0006955//immune response;GO:0046039//GTP metabolic process","K01064//wingless-type MMTV integration site family, member 9","NP_004277.2//GTP-binding protein 1 [Homo sapiens]",4]
[6209,550,537.76,736.46,0.453644721265268,{"v":3.24821608787879e-44,"d":"3.25E-44"},"*",{"v":5.36828e-46,"d":"5.37E-46"},"RPS15","GO:0022627//cytosolic small ribosomal subunit;GO:0015935//small ribosomal subunit","GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome","GO:0000028//ribosomal small subunit assembly;GO:0006412//translation","K02958//small subunit ribosomal protein S15e","XP_001373175.3//PREDICTED: 40S ribosomal protein S15 [Monodelphis domestica];NP_001295155.1//40S ribosomal protein S15 isoform 1 [Homo sapiens]","1//3;4"]
[79090,752,18.11,24.79,0.452971725136554,0.00940712471918308,"*",0.00322954,"TRAPPC6A","GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0030008//TRAPP complex;GO:0005802//trans-Golgi network;GO:0005801//cis-Golgi network;GO:0000139//Golgi membrane","GO:0017112//Rab guanyl-nucleotide exchange factor activity","GO:0048208//COPII vesicle coating;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0061024//membrane organization;GO:1903232//melanosome assembly","K20304//trafficking protein particle complex subunit 6","NP_077013.1//trafficking protein particle complex subunit 6A isoform 1 [Homo sapiens];NP_001257820.1//trafficking protein particle complex subunit 6A isoform 2 [Homo sapiens];XP_012352306.1//PREDICTED: trafficking protein particle complex subunit 6A isoform X4 [Nomascus leucogenys];XP_012352305.1//PREDICTED: trafficking protein particle complex subunit 6A isoform X3 [Nomascus leucogenys]","1//3;2//1"]
[114897,2737,16.3,22.31,0.452818549125701,{"v":4.85595176523702e-08,"d":"4.86E-08"},"*",{"v":6.7334e-09,"d":"6.73E-09"},"C1QTNF1","GO:0005634//nucleus;GO:0005615//extracellular space;GO:0005887//integral component of plasma membrane;GO:0005829//cytosol;GO:0005576//extracellular region;GO:0005581//collagen trimer","GO:0005518//collagen binding","GO:0051897//positive regulation of protein kinase B signaling;GO:0051260//protein homooligomerization;GO:0010628//positive regulation of gene expression;GO:2000860//positive regulation of aldosterone secretion;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0043410//positive regulation of MAPK cascade;GO:0070208//protein heterotrimerization;GO:0010906//regulation of glucose metabolic process;GO:0090331//negative regulation of platelet aggregation","K19470//complement C1q tumor necrosis factor-related protein 6","XP_008046495.1//complement C1q tumor necrosis factor-related protein 1 [Carlito syrichta];XP_005407403.1//PREDICTED: complement C1q tumor necrosis factor-related protein 1 isoform X1 [Chinchilla lanigera]","4;3//A2MP1;2//1"]
[6610,1697,9.55,13.07,0.452686502872322,0.00212945398826979,"*",0.00063641,"SMPD2","GO:0005901//caveola;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005622//intracellular;GO:0005886//plasma membrane","GO:0046872//metal ion binding;GO:0004767//sphingomyelin phosphodiesterase activity","GO:2000304//positive regulation of ceramide biosynthetic process;GO:0009612//response to mechanical stimulus;GO:0035556//intracellular signal transduction;GO:0006684//sphingomyelin metabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0046513//ceramide biosynthetic process","K12351//sphingomyelin phosphodiesterase 2 [EC:3.1.4.12]","NP_003071.2//sphingomyelin phosphodiesterase 2 [Homo sapiens]","2//1"]
[79792,1772,10.69,14.63,0.452667916417996,0.00116868732612056,"*",3.3135E-4,"GSDMD","GO:1904724//tertiary granule lumen;GO:0005654//nucleoplasm;GO:0005615//extracellular space;GO:0035580//specific granule lumen;GO:0072559//NLRP3 inflammasome complex;GO:0005829//cytosol;GO:0005576//extracellular region;GO:1904813//ficolin-1-rich granule lumen;GO:0005886//plasma membrane","GO:1901612//cardiolipin binding;GO:0070273//phosphatidylinositol-4-phosphate binding;GO:0070300//phosphatidic acid binding;GO:0001786//phosphatidylserine binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding","GO:0046931//pore complex assembly;GO:0070269//pyroptosis;GO:0050718//positive regulation of interleukin-1 beta secretion;GO:0050829//defense response to Gram-negative bacterium;GO:0019835//cytolysis;GO:0051260//protein homooligomerization;GO:0006954//inflammatory response;GO:0035915//pore formation in membrane of other organism;GO:0043312//neutrophil degranulation;GO:0050830//defense response to Gram-positive bacterium;GO:0045087//innate immune response;GO:0031668//cellular response to extracellular stimulus","K20917//gasdermin-D","EAW82246.1//gasdermin domain containing 1, isoform CRA_d [Homo sapiens]","6;1//3"]
[284739,2669,0.38,0.52,0.452512204697507,0.51407080060992,"*",0.358794,"C20orf204","NA","NA","NA","K16628//collagen, type VII, alpha;K00894//ethanolamine kinase [EC:2.7.1.82];K06236//collagen, type I, alpha;K03145//transcription elongation factor S-II","NP_001335019.1//putative uncharacterized protein C20orf204 precursor [Homo sapiens]","1//3"]
[26233,1797,15.28,20.9,0.451858398932496,{"v":3.61944371995333e-05,"d":"3.62E-05"},"*",{"v":7.76728e-06,"d":"7.77E-06"},"FBXL6","NA","GO:0004842//ubiquitin-protein transferase activity","GO:0006508//proteolysis","K10272//F-box and leucine-rich repeat protein 6","NP_078831.4//F-box/LRR-repeat protein 6 isoform 2 [Homo sapiens];NP_036294.2//F-box/LRR-repeat protein 6 isoform 1 [Homo sapiens]","3//A2MP1;5"]
[10557,1379,16.22,22.18,0.451485545944437,0.0186320327444052,"*",0.0069319,"RPP38","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005655//nucleolar ribonuclease P complex;GO:0001650//fibrillar center","GO:0004526//ribonuclease P activity","GO:0001682//tRNA 5'-leader removal;GO:0006364//rRNA processing","K14523//ribonucleases P/MRP protein subunit RPP38 [EC:3.1.26.5]","XP_016801925.1//PREDICTED: ribonuclease P protein subunit p38 isoform X1 [Pan troglodytes];NP_892117.1//ribonuclease P protein subunit p38 [Homo sapiens]","4;1//3;2//1"]
[6710,9801,0.49,0.67,0.451379346342564,0.161139281920078,"*",0.082799,"SPTB","NA","NA","NA","K06115//spectrin beta","XP_012579934.1//PREDICTED: spectrin beta chain, erythrocytic isoform X1 [Condylura cristata];XP_004681841.1//PREDICTED: spectrin beta chain, erythrocytic isoform X2 [Condylura cristata]","1//3;3//A2MP1"]
[83442,1131,132.17,180.71,0.45128159273138,{"v":2.0549170371567e-23,"d":"2.05E-23"},"*",{"v":7.9629e-25,"d":"7.96E-25"},"SH3BGRL3","NA","NA","NA","K16342//cytosolic phospholipase A2 [EC:3.1.1.4];K13912//deleted in malignant brain tumors 1 protein","EAX07831.1//SH3 domain binding glutamic acid-rich protein like 3, isoform CRA_a, partial [Homo sapiens]","3//A2MP1"]
[11119,3581,2.18,2.98,0.450984195685235,0.033732440655533,"*",0.01352972,"BTN3A1","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","NA","GO:0050663//cytokine secretion;GO:0050798//activated T cell proliferation;GO:0072643//interferon-gamma secretion;GO:0050852//T cell receptor signaling pathway;GO:0002250//adaptive immune response","K06712//butyrophilin","NP_001138480.1//butyrophilin subfamily 3 member A1 isoform c precursor [Homo sapiens];NP_001138481.1//butyrophilin subfamily 3 member A1 isoform d precursor [Homo sapiens];NP_919423.1//butyrophilin subfamily 3 member A1 isoform b precursor [Homo sapiens];NP_008979.3//butyrophilin subfamily 3 member A1 isoform a precursor [Homo sapiens]","1//3;2//1;5"]
[84300,1355,13.25,18.11,0.450794186612244,0.0012646445476086,"*",0.000360852,"UQCC2","GO:0005759//mitochondrial matrix;GO:0042645//mitochondrial nucleoid;GO:0016604//nuclear body;GO:0005758//mitochondrial intermembrane space;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","NA","GO:1903364//positive regulation of cellular protein catabolic process;GO:0034551//mitochondrial respiratory chain complex III assembly;GO:2001014//regulation of skeletal muscle cell differentiation;GO:0070131//positive regulation of mitochondrial translation;GO:0002082//regulation of oxidative phosphorylation;GO:0050796//regulation of insulin secretion","K17682//mitochondrial nucleoid factor 1","XP_003923203.1//PREDICTED: ubiquinol-cytochrome-c reductase complex assembly factor 2 [Saimiri boliviensis boliviensis]","3//A2MP1"]
[84266,1331,13.99,19.12,0.450686560815995,0.000996329156906571,"*",0.000279052,"ALKBH7","GO:0005759//mitochondrial matrix","GO:0046872//metal ion binding;GO:0051213//dioxygenase activity","GO:1902445//regulation of mitochondrial membrane permeability involved in programmed necrotic cell death;GO:0006631//fatty acid metabolic process;GO:0010883//regulation of lipid storage;GO:0006974//cellular response to DNA damage stimulus","K10769//alkylated DNA repair protein alkB homolog 7 [EC:1.14.11.-]","XP_017383808.1//PREDICTED: alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial [Cebus capucinus imitator]","3//A2MP1"]
[643988,2104,11.24,15.36,0.45053618050023,0.000159298618647166,"*",{"v":3.81842e-05,"d":"3.82E-05"},"FNDC10","GO:0016021//integral component of membrane","NA","NA","K16628//collagen, type VII, alpha;K11094//U2 small nuclear ribonucleoprotein B'';K15544//RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]","NP_001229588.1//fibronectin type III domain-containing protein 10 precursor [Homo sapiens]","1//3"]
[51310,2113,5.38,7.35,0.450138077167103,0.00422918093663912,"*",1.34548E-3,"SLC22A17","GO:0005774//vacuolar membrane;GO:0005887//integral component of plasma membrane;GO:0031301//integral component of organelle membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004888//transmembrane signaling receptor activity;GO:0008514//organic anion transmembrane transporter activity;GO:0022857//transmembrane transporter activity","GO:0006879//cellular iron ion homeostasis;GO:0015891//siderophore transport","K08213//MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 17","XP_014711772.1//PREDICTED: solute carrier family 22 member 17 isoform X1 [Equus asinus];XP_013012739.1//PREDICTED: solute carrier family 22 member 17 [Cavia porcellus];XP_003808140.1//PREDICTED: solute carrier family 22 member 17 isoform X2 [Pan paniscus]","4;1//3;3//A2MP1"]
[27106,2540,12,16.39,0.449781448603578,{"v":1.53668678947368e-05,"d":"1.54E-05"},"*",{"v":3.07068E-6,"d":"3.07E-06"},"ARRDC2","GO:0031410//cytoplasmic vesicle;GO:0005886//plasma membrane","NA","NA","K20910//thioredoxin-interacting protein","NP_056498.1//arrestin domain-containing protein 2 isoform 1 [Homo sapiens];XP_017356769.1//PREDICTED: arrestin domain-containing protein 2 isoform X1 [Cebus capucinus imitator];NP_001273755.1//arrestin domain-containing protein 2 isoform 3 [Homo sapiens]","1//3;2//1"]
[10084,938,57.99,79.19,0.44951412206895,{"v":4.84621517525773e-07,"d":"4.85E-07"},"*",{"v":7.65128e-08,"d":"7.65E-08"},"PQBP1","GO:0010494//cytoplasmic stress granule;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0071598//neuronal ribonucleoprotein granule","GO:0003677//DNA binding;GO:0003713//transcription coactivator activity;GO:0043021//ribonucleoprotein complex binding;GO:0003690//double-stranded DNA binding","GO:0043484//regulation of RNA splicing;GO:0032481//positive regulation of type I interferon production;GO:0000398//mRNA splicing, via spliceosome;GO:0006355//regulation of transcription, DNA-templated;GO:0002218//activation of innate immune response;GO:0051607//defense response to virus;GO:0071360//cellular response to exogenous dsRNA;GO:0006351//transcription, DNA-templated;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0031175//neuron projection development;GO:0048814//regulation of dendrite morphogenesis;GO:0045087//innate immune response;GO:0002230//positive regulation of defense response to virus by host","K12865//polyglutamine-binding protein 1","XP_012354320.1//PREDICTED: polyglutamine-binding protein 1 isoform X1 [Nomascus leucogenys];XP_017379387.1//PREDICTED: polyglutamine-binding protein 1 isoform X3 [Cebus capucinus imitator];XP_008957541.1//PREDICTED: polyglutamine-binding protein 1 isoform X1 [Pan paniscus];XP_008957542.1//PREDICTED: polyglutamine-binding protein 1 isoform X2 [Pan paniscus];EAW50738.1//polyglutamine binding protein 1, isoform CRA_d [Homo sapiens];NP_001161464.1//polyglutamine-binding protein 1 isoform 6 [Homo sapiens]","1//3;2//1"]
[8000,1038,2.38,3.25,0.449478144607873,0.32083571458508,"*",0.19169,"PSCA","GO:0070062//extracellular exosome;GO:0005886//plasma membrane","GO:0033130//acetylcholine receptor binding","GO:0099601//regulation of neurotransmitter receptor activity;GO:0070373//negative regulation of ERK1 and ERK2 cascade","K06846//lymphocyte antigen 6 complex locus protein D/E/G6/H","XP_003819533.1//PREDICTED: prostate stem cell antigen [Pan paniscus]",4]
[435,1969,7.67,10.47,0.448962959427875,0.00414069889826498,"*",1.314738E-3,"ASL","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0004056//argininosuccinate lyase activity;GO:0042802//identical protein binding","GO:0007626//locomotory behavior;GO:0009791//post-embryonic development;GO:0042450//arginine biosynthetic process via ornithine;GO:0000050//urea cycle;GO:0019676//ammonia assimilation cycle","K01755//argininosuccinate lyase [EC:4.3.2.1]","NP_001020117.1//argininosuccinate lyase isoform 3 [Homo sapiens];NP_000039.2//argininosuccinate lyase isoform 1 [Homo sapiens];NP_001020115.1//argininosuccinate lyase isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[84798,1518,150.19,205.01,0.448905525328159,{"v":1.67977066518106E-34,"d":"1.68E-34"},"*",{"v":3.77512e-36,"d":"3.78E-36"},"C19orf48","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein;K12642//plakophilin 2","XP_004089434.1//PREDICTED: uncharacterized protein C19orf48 homolog [Nomascus leucogenys]","1//3;2//1"]
[84987,757,27.78,37.91,0.448531857189251,4.80977940797326E-4,"*",1.26131E-4,"COX14","GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0031966//mitochondrial membrane","NA","GO:0033617//mitochondrial respiratory chain complex IV assembly","K18181//cytochrome c oxidase assembly factor 14","EHH20721.1//hypothetical protein EGK_03635 [Macaca mulatta]","1//3;3//A2MP1"]
[22839,3781,24.64,33.62,0.448317468541266,{"v":3.93608465046102e-14,"d":"3.94E-14"},"*",{"v":2.93962e-15,"d":"2.94E-15"},"DLGAP4","GO:0045202//synapse;GO:0005886//plasma membrane","GO:0019904//protein domain specific binding","GO:0023052//signaling;GO:0006461//protein complex assembly","K15008//discs, large-associated protein 1","XP_021776782.1//disks large-associated protein 4 isoform X7 [Papio anubis];NP_892118.1//disks large-associated protein 4 isoform b [Homo sapiens];NP_055717.2//disks large-associated protein 4 isoform a [Homo sapiens]","3//A2MP1;5"]
[59286,476,89.81,122.53,0.448187021445484,{"v":2.94877912372941e-06,"d":"2.95E-06"},"*",{"v":5.2666e-07,"d":"5.27E-07"},"UBL5","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0031386//protein tag","GO:0000398//mRNA splicing, via spliceosome;GO:0006464//cellular protein modification process;GO:1903955//positive regulation of protein targeting to mitochondrion","K13113//ubiquitin-like protein 5","XP_007104382.1//PREDICTED: ubiquitin-like protein 5 isoform X1 [Physeter catodon];XP_004464750.1//PREDICTED: ubiquitin-like protein 5 [Dasypus novemcinctus]","3//A2MP1;2//1"]
[54556,1921,1.62,2.21,0.448052556506807,0.352110747765334,"*",0.214542,"ING3","GO:0000812//Swr1 complex;GO:0035267//NuA4 histone acetyltransferase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0032777//Piccolo NuA4 histone acetyltransferase complex","GO:0046872//metal ion binding;GO:0004402//histone acetyltransferase activity;GO:0035064//methylated histone binding","GO:0043065//positive regulation of apoptotic process;GO:0043967//histone H4 acetylation;GO:0016569//covalent chromatin modification;GO:0006355//regulation of transcription, DNA-templated;GO:0040008//regulation of growth;GO:0043968//histone H2A acetylation;GO:0006351//transcription, DNA-templated","K11319//inhibitor of growth protein 3","AAF28979.1//HSPC301, partial [Homo sapiens];NP_061944.2//inhibitor of growth protein 3 isoform 1 [Homo sapiens]","1//3;2//1"]
[2877,1105,147.59,201.32,0.447895528426845,{"v":4.72224827099099e-25,"d":"4.72E-25"},"*",{"v":1.640696e-26,"d":"1.64E-26"},"GPX2","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0009055//electron transfer activity;GO:0004602//glutathione peroxidase activity","GO:0034599//cellular response to oxidative stress","K00432//glutathione peroxidase [EC:1.11.1.9]","NP_002074.2//glutathione peroxidase 2 [Homo sapiens]","3//A2MP1"]
[2274,1568,17.64,24.06,0.447786081618556,{"v":2.36297374848851e-05,"d":"2.36E-05"},"*",{"v":4.8934e-06,"d":"4.89E-06"},"FHL2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0030018//Z disc;GO:0031430//M band;GO:0005925//focal adhesion","GO:0046872//metal ion binding;GO:0003713//transcription coactivator activity;GO:0050681//androgen receptor binding;GO:0042802//identical protein binding;GO:0008134//transcription factor binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0055015//ventricular cardiac muscle cell development;GO:0001649//osteoblast differentiation;GO:0055014//atrial cardiac muscle cell development;GO:0006351//transcription, DNA-templated;GO:0043066//negative regulation of apoptotic process;GO:0030521//androgen receptor signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0009725//response to hormone;GO:0060347//heart trabecula formation;GO:0019216//regulation of lipid metabolic process","K14380//four and a half LIM domains protein 2","XP_003922830.1//PREDICTED: four and a half LIM domains protein 2 isoform X1 [Saimiri boliviensis boliviensis];XP_012351184.1//PREDICTED: four and a half LIM domains protein 2 isoform X1 [Nomascus leucogenys];ABB73038.1//FHL2 isoform 5 [Homo sapiens];XP_004031594.2//PREDICTED: LOW QUALITY PROTEIN: four and a half LIM domains protein 2 [Gorilla gorilla gorilla];XP_003775909.1//PREDICTED: four and a half LIM domains protein 2 isoform X1 [Pongo abelii];XP_017730526.1//PREDICTED: four and a half LIM domains protein 2 isoform X2 [Rhinopithecus bieti];XP_002811776.1//PREDICTED: four and a half LIM domains protein 2 isoform X3 [Pongo abelii]","1//3;3//A2MP1;2//1"]
[7108,1613,8.66,11.81,0.447570034670432,5.27319625945946E-3,"*",1.709976E-3,"TM7SF2","GO:0043231//intracellular membrane-bounded organelle;GO:0005783//endoplasmic reticulum;GO:0005887//integral component of plasma membrane;GO:0031090//organelle membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0043235//receptor complex","GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors;GO:0050661//NADP binding;GO:0016628//oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;GO:0050613//delta14-sterol reductase activity","GO:0016126//sterol biosynthetic process;GO:0006695//cholesterol biosynthetic process;GO:0045540//regulation of cholesterol biosynthetic process","K00222//Delta14-sterol reductase [EC:1.3.1.70]","NP_001264162.1//delta(14)-sterol reductase isoform 2 [Homo sapiens];NP_003264.2//delta(14)-sterol reductase isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[5129,3134,0.99,1.35,0.447458976971221,0.301354636761722,"*",0.176636,"CDK18","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity","GO:0006468//protein phosphorylation","K15596//cyclin-dependent kinase 18 [EC:2.7.11.22]","XP_016856912.1//PREDICTED: cyclin-dependent kinase 18 isoform X1 [Homo sapiens];XP_011507904.1//PREDICTED: cyclin-dependent kinase 18 isoform X2 [Homo sapiens]","3//A2MP1;2//1"]
[1636,4687,0.11,0.15,0.447458976971221,0.868838438209118,"*",0.800578,"ACE","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0009897//external side of plasma membrane;GO:0005764//lysosome;GO:0005768//endosome;GO:0005576//extracellular region;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004175//endopeptidase activity;GO:0004180//carboxypeptidase activity;GO:0031711//bradykinin receptor binding;GO:0008241//peptidyl-dipeptidase activity;GO:0031434//mitogen-activated protein kinase kinase binding;GO:0008238//exopeptidase activity;GO:0008240//tripeptidyl-peptidase activity;GO:0003779//actin binding;GO:0031404//chloride ion binding;GO:0070573//metallodipeptidase activity;GO:0046872//metal ion binding;GO:0051019//mitogen-activated protein kinase binding;GO:0008237//metallopeptidase activity;GO:0008144//drug binding;GO:0008270//zinc ion binding","GO:0008217//regulation of blood pressure;GO:2000170//positive regulation of peptidyl-cysteine S-nitrosylation;GO:0010608//posttranscriptional regulation of gene expression;GO:0032092//positive regulation of protein binding;GO:0050435//amyloid-beta metabolic process;GO:0050482//arachidonic acid secretion;GO:0071838//cell proliferation in bone marrow;GO:0032091//negative regulation of protein binding;GO:0060177//regulation of angiotensin metabolic process;GO:0002005//angiotensin catabolic process in blood;GO:0097746//regulation of blood vessel diameter;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0043171//peptide catabolic process;GO:0001974//blood vessel remodeling;GO:0006508//proteolysis;GO:0060047//heart contraction;GO:1903597//negative regulation of gap junction assembly;GO:0032943//mononuclear cell proliferation;GO:1900086//positive regulation of peptidyl-tyrosine autophosphorylation;GO:0002019//regulation of renal output by angiotensin;GO:0001822//kidney development;GO:0019229//regulation of vasoconstriction;GO:0010629//negative regulation of gene expression;GO:0007283//spermatogenesis;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0002446//neutrophil mediated immunity;GO:0002003//angiotensin maturation;GO:0042447//hormone catabolic process;GO:0060218//hematopoietic stem cell differentiation;GO:0003084//positive regulation of systemic arterial blood pressure;GO:1902033//regulation of hematopoietic stem cell proliferation;GO:0003081//regulation of systemic arterial blood pressure by renin-angiotensin;GO:0014910//regulation of smooth muscle cell migration","K01283//peptidyl-dipeptidase A [EC:3.4.15.1]","XP_011803323.1//PREDICTED: angiotensin-converting enzyme isoform X3 [Colobus angolensis palliatus];NP_000780.1//angiotensin-converting enzyme isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1;2//1"]
[284307,4294,0.11,0.15,0.447458976971221,0.578735426951817,"*",0.421824,"ZIK1","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","XP_012606836.1//zinc finger protein interacting with ribonucleoprotein K isoform X1 [Microcebus murinus]","1//3;3//A2MP1"]
[2700,5219,0.11,0.15,0.447458976971221,0.634369083810948,"*",0.4781,"GJA3","GO:0005922//connexin complex;GO:0016021//integral component of membrane","GO:0005243//gap junction channel activity","GO:0006810//transport;GO:0007154//cell communication;GO:0007267//cell-cell signaling;GO:0007601//visual perception","K07612//gap junction alpha-3 protein","NP_068773.2//gap junction alpha-3 protein [Homo sapiens]","3//A2MP1"]
[4237,1105,0.22,0.3,0.447458976971221,0.810328436664099,"*",0.724446,"MFAP2","GO:0001527//microfibril;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix","NA","GO:0048050//post-embryonic eye morphogenesis;GO:0030198//extracellular matrix organization;GO:0048048//embryonic eye morphogenesis","K13526//cation-transporting P-type ATPase 13A2 [EC:3.6.3.-]","XP_007978520.1//PREDICTED: microfibrillar-associated protein 2 isoform X2 [Chlorocebus sabaeus];XP_007978519.1//PREDICTED: microfibrillar-associated protein 2 isoform X1 [Chlorocebus sabaeus]","1//3;3//A2MP1;2//1"]
[65991,2981,18.16,24.76,0.44724711192335,{"v":4.37545314759192e-09,"d":"4.38E-09"},"*",{"v":5.28922e-10,"d":"5.29E-10"},"FUNDC2","GO:0005634//nucleus;GO:0031307//integral component of mitochondrial outer membrane;GO:0005739//mitochondrion","NA","GO:0000422//autophagy of mitochondrion","K17986//FUN14 domain-containing protein 1;K16524//A-kinase anchor protein 7","XP_017371700.1//PREDICTED: FUN14 domain-containing protein 2 [Cebus capucinus imitator]","3//A2MP1"]
[7494,1810,21.61,29.46,0.447058358176342,{"v":8.6635086402439e-07,"d":"8.66E-07"},"*",{"v":1.423128E-7,"d":"1.42E-07"},"XBP1","GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005789//endoplasmic reticulum membrane;GO:0005737//cytoplasm","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity;GO:0001158//enhancer sequence-specific DNA binding;GO:0031490//chromatin DNA binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0001047//core promoter binding","GO:0030335//positive regulation of cell migration;GO:1903489//positive regulation of lactation;GO:1900100//positive regulation of plasma cell differentiation;GO:0071222//cellular response to lipopolysaccharide;GO:0042593//glucose homeostasis;GO:1990418//response to insulin-like growth factor stimulus;GO:0006914//autophagy;GO:0045348//positive regulation of MHC class II biosynthetic process;GO:1900103//positive regulation of endoplasmic reticulum unfolded protein response;GO:2000347//positive regulation of hepatocyte proliferation;GO:0001935//endothelial cell proliferation;GO:0001525//angiogenesis;GO:0045600//positive regulation of fat cell differentiation;GO:0043066//negative regulation of apoptotic process;GO:0071375//cellular response to peptide hormone stimulus;GO:1990830//cellular response to leukemia inhibitory factor;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:1902236//negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway;GO:0035356//cellular triglyceride homeostasis;GO:0002639//positive regulation of immunoglobulin production;GO:0042149//cellular response to glucose starvation;GO:1901800//positive regulation of proteasomal protein catabolic process;GO:0055089//fatty acid homeostasis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0045582//positive regulation of T cell differentiation;GO:0042632//cholesterol homeostasis;GO:0071353//cellular response to interleukin-4;GO:0010506//regulation of autophagy;GO:0031648//protein destabilization;GO:0001889//liver development;GO:0006990//positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response;GO:0060612//adipose tissue development;GO:0060691//epithelial cell maturation involved in salivary gland development;GO:0071230//cellular response to amino acid stimulus;GO:0035470//positive regulation of vascular wound healing;GO:0031017//exocrine pancreas development;GO:0036500//ATF6-mediated unfolded protein response","K09027//X box-binding protein 1","NP_001073007.1//X-box-binding protein 1 isoform XBP1(S) [Homo sapiens];NP_005071.2//X-box-binding protein 1 isoform XBP1(U) [Homo sapiens]","1//3;3//A2MP1"]
[5646,803,9.45,12.88,0.446746359006182,0.0550690482054275,"*",0.0236286,"PRSS3","GO:1904724//tertiary granule lumen;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005576//extracellular region","GO:0004252//serine-type endopeptidase activity;GO:0005509//calcium ion binding;GO:0008236//serine-type peptidase activity","GO:0006508//proteolysis;GO:0043542//endothelial cell migration;GO:0007586//digestion;GO:0043312//neutrophil degranulation;GO:0031638//zymogen activation;GO:0019730//antimicrobial humoral response;GO:0009235//cobalamin metabolic process","K01312//trypsin [EC:3.4.21.4]","NP_001184026.2//trypsin-3 isoform 3 preproprotein [Homo sapiens];NP_002762.2//trypsin-3 isoform 2 preproprotein [Homo sapiens];NP_031369.2//trypsin-3 isoform 1 preproprotein [Homo sapiens];NP_001184027.1//trypsin-3 isoform 4 preproprotein [Homo sapiens]","1//3;3//A2MP1;2//1"]
[79586,2914,13.48,18.37,0.446531129929491,{"v":9.72662051851852e-07,"d":"9.73E-07"},"*",{"v":1.611158e-07,"d":"1.61E-07"},"CHPF","GO:0005759//mitochondrial matrix;GO:0032580//Golgi cisterna membrane;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0046872//metal ion binding;GO:0047238//glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity;GO:0008376//acetylgalactosaminyltransferase activity;GO:0050510//N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity","GO:0030206//chondroitin sulfate biosynthetic process","K00747//chondroitin polymerizing factor [EC:2.4.1.175 2.4.1.226]","XP_006059009.1//PREDICTED: chondroitin sulfate synthase 2 [Bubalus bubalis];NP_078812.2//chondroitin sulfate synthase 2 isoform 1 [Homo sapiens]","1//3;5"]
[127687,1227,34.53,47.04,0.446037725982978,{"v":4.00485701521217e-07,"d":"4.00E-07"},"*",{"v":6.26276e-08,"d":"6.26E-08"},"C1orf122","NA","NA","NA","K16628//collagen, type VII, alpha;K13172//serine/arginine repetitive matrix protein 2","EAX07314.1//chromosome 1 open reading frame 122, isoform CRA_b, partial [Homo sapiens];EAX07316.1//chromosome 1 open reading frame 122, isoform CRA_d, partial [Homo sapiens]","1//3;2//1"]
[55888,1782,1.74,2.37,0.445799753049531,0.338993664974619,"*",0.204852,"ZKSCAN7","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein;K09229//KRAB and SCAN domains-containing zinc finger protein","XP_011888676.1//PREDICTED: zinc finger protein with KRAB and SCAN domains 7 isoform X3 [Cercocebus atys];XP_004034009.2//PREDICTED: LOW QUALITY PROTEIN: zinc finger protein with KRAB and SCAN domains 7 [Gorilla gorilla gorilla];NP_079445.1//zinc finger protein with KRAB and SCAN domains 7 isoform 2 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[2675,2977,0.47,0.64,0.445411148322363,0.458518621599034,"*",0.309114,"GFRA2","GO:0019898//extrinsic component of membrane;GO:0005622//intracellular;GO:0005886//plasma membrane;GO:0031225//anchored component of membrane","GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0016167//glial cell-derived neurotrophic factor receptor activity","GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0000165//MAPK cascade;GO:0033141//positive regulation of peptidyl-serine phosphorylation of STAT protein;GO:0031953//negative regulation of protein autophosphorylation;GO:0007411//axon guidance","K19895//GDNF family receptor alpha 1","NP_001158510.1//GDNF family receptor alpha-2 isoform b precursor [Homo sapiens];NP_001158511.1//GDNF family receptor alpha-2 isoform c precursor [Homo sapiens];NP_001486.4//GDNF family receptor alpha-2 isoform a preproprotein [Homo sapiens]","1//3;4"]
[101927322,1215,0.94,1.28,0.445411148322363,0.5426633125164,"*",0.388398,"LOC101927322","NA","NA","NA","K07369//mucosa-associated lymphoid tissue lymphoma translocation protein 1 [EC:3.4.22.-]","XP_017384310.1//PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein LOC108304565 [Cebus capucinus imitator]","1//3"]
[9416,3288,41.44,56.42,0.445182662899018,{"v":2.03565678850575E-21,"d":"2.04E-21"},"*",{"v":8.86952e-23,"d":"8.87E-23"},"DDX23","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005682//U5 snRNP;GO:0005737//cytoplasm;GO:0071013//catalytic step 2 spliceosome","GO:0003723//RNA binding;GO:0004004//ATP-dependent RNA helicase activity;GO:0005524//ATP binding;GO:0004386//helicase activity;GO:0003676//nucleic acid binding","GO:0000398//mRNA splicing, via spliceosome;GO:0000354//cis assembly of pre-catalytic spliceosome;GO:0008380//RNA splicing;GO:0010501//RNA secondary structure unwinding;GO:0000375//RNA splicing, via transesterification reactions","K12858//ATP-dependent RNA helicase DDX23/PRP28 [EC:3.6.4.13]","XP_016007227.1//PREDICTED: probable ATP-dependent RNA helicase DDX23 isoform X1 [Rousettus aegyptiacus]","2//1"]
[342977,846,1.08,1.47,0.444784842672896,0.595837935264633,"*",0.439064,"NANOS3","GO:0010494//cytoplasmic stress granule;GO:0005634//nucleus;GO:0000932//P-body;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm","GO:0003723//RNA binding;GO:0008270//zinc ion binding","GO:0048477//oogenesis;GO:0007283//spermatogenesis;GO:0006417//regulation of translation;GO:1900153//positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0007281//germ cell development;GO:0017148//negative regulation of translation;GO:0007275//multicellular organism development;GO:0051726//regulation of cell cycle;GO:2001234//negative regulation of apoptotic signaling pathway","K18761//protein nanos 3","NP_001092092.1//nanos homolog 3 [Homo sapiens]","2//1"]
[84549,3590,14.22,19.35,0.444412101412358,{"v":1.50078457643098e-08,"d":"1.50E-08"},"*",{"v":1.953256e-09,"d":"1.95E-09"},"MAK16","GO:0005730//nucleolus;GO:0030687//preribosome, large subunit precursor","GO:0003723//RNA binding","GO:0000470//maturation of LSU-rRNA;GO:0000460//maturation of 5.8S rRNA","K14831//protein MAK16","XP_012631195.1//protein MAK16 homolog isoform X2 [Microcebus murinus]","3//A2MP1"]
[91355,1997,1.83,2.49,0.444302093784038,0.862206469859001,"*",0.792416,"LRP5L","NA","NA","NA","K03068//low density lipoprotein receptor-related protein 5/6","XP_008965145.1//PREDICTED: low-density lipoprotein receptor-related protein 5-like protein isoform X3 [Pan paniscus];XP_015289840.1//PREDICTED: LOW QUALITY PROTEIN: low-density lipoprotein receptor-related protein 5-like protein [Macaca fascicularis]","1//3;2//1"]
[84299,1506,48.62,66.15,0.44419126313731,{"v":1.23307067795222e-11,"d":"1.23E-11"},"*",{"v":1.130868e-12,"d":"1.13E-12"},"MIEN1","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0031235//intrinsic component of the cytoplasmic side of the plasma membrane","NA","GO:0051491//positive regulation of filopodium assembly;GO:0030335//positive regulation of cell migration;GO:0043066//negative regulation of apoptotic process;GO:0006915//apoptotic process","K07401//selenoprotein W-related protein","EAW60599.1//chromosome 17 open reading frame 37, isoform CRA_b [Homo sapiens];XP_007531013.1//PREDICTED: migration and invasion enhancer 1 [Erinaceus europaeus]","1//3;4"]
[64077,1630,6.47,8.8,0.443737811532152,0.00230633975026015,"*",0.00069375,"LHPP","GO:0005634//nucleus;GO:0005829//cytosol;GO:0016607//nuclear speck","GO:0000287//magnesium ion binding;GO:0101006//protein histidine phosphatase activity;GO:0004427//inorganic diphosphatase activity;GO:0042803//protein homodimerization activity;GO:0016791//phosphatase activity","GO:0006470//protein dephosphorylation;GO:0016311//dephosphorylation;GO:0009168//purine ribonucleoside monophosphate biosynthetic process;GO:0006796//phosphate-containing compound metabolic process","K11725//phospholysine phosphohistidine inorganic pyrophosphate phosphatase [EC:3.6.1.1 3.1.3.-]","XP_010355879.1//PREDICTED: phospholysine phosphohistidine inorganic pyrophosphate phosphatase isoform X3 [Rhinopithecus roxellana];NP_071409.3//phospholysine phosphohistidine inorganic pyrophosphate phosphatase isoform 1 [Homo sapiens];NP_001305260.1//phospholysine phosphohistidine inorganic pyrophosphate phosphatase isoform 3 [Homo sapiens];XP_016871998.1//PREDICTED: phospholysine phosphohistidine inorganic pyrophosphate phosphatase isoform X1 [Homo sapiens]","1//3;3//A2MP1"]
[54,1507,0.25,0.34,0.443606651475615,0.695216835502068,"*",0.578622,"ACP5","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005764//lysosome","GO:0008199//ferric iron binding;GO:0003993//acid phosphatase activity;GO:0008198//ferrous iron binding","GO:0045453//bone resorption;GO:0060349//bone morphogenesis;GO:0034097//response to cytokine;GO:0032695//negative regulation of interleukin-12 production;GO:0032496//response to lipopolysaccharide;GO:0032720//negative regulation of tumor necrosis factor production;GO:0045019//negative regulation of nitric oxide biosynthetic process;GO:0032691//negative regulation of interleukin-1 beta production;GO:0032929//negative regulation of superoxide anion generation;GO:0050728//negative regulation of inflammatory response;GO:0006771//riboflavin metabolic process;GO:0050830//defense response to Gram-positive bacterium","K14379//tartrate-resistant acid phosphatase type 5 [EC:3.1.3.2]","XP_017724910.1//PREDICTED: tartrate-resistant acid phosphatase type 5 isoform X2 [Rhinopithecus bieti]","4;1//3;2//1"]
[8326,2342,1.78,2.42,0.443129806308197,0.165868309477005,"*",0.0855716,"FZD9","GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0009986//cell surface;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0031966//mitochondrial membrane;GO:0031527//filopodium membrane;GO:0005886//plasma membrane","GO:0004888//transmembrane signaling receptor activity;GO:0042813//Wnt-activated receptor activity;GO:0046982//protein heterodimerization activity;GO:0017147//Wnt-protein binding;GO:0042803//protein homodimerization activity;GO:0004930//G-protein coupled receptor activity","GO:0007399//nervous system development;GO:0001503//ossification;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0007405//neuroblast proliferation;GO:0043065//positive regulation of apoptotic process;GO:0030183//B cell differentiation;GO:0071157//negative regulation of cell cycle arrest;GO:0007611//learning or memory;GO:0001836//release of cytochrome c from mitochondria;GO:0035567//non-canonical Wnt signaling pathway;GO:0043524//negative regulation of neuron apoptotic process;GO:0060546//negative regulation of necroptotic process;GO:1901029//negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:2000179//positive regulation of neural precursor cell proliferation;GO:0060070//canonical Wnt signaling pathway;GO:0030501//positive regulation of bone mineralization;GO:0051902//negative regulation of mitochondrial depolarization;GO:0007275//multicellular organism development;GO:0016055//Wnt signaling pathway;GO:1904393//regulation of skeletal muscle acetylcholine-gated channel clustering;GO:1904394//negative regulation of skeletal muscle acetylcholine-gated channel clustering;GO:1990523//bone regeneration","K02842//frizzled 9/10","XP_011765634.1//PREDICTED: frizzled-9 [Macaca nemestrina]","2//1"]
[389541,615,45.44,61.77,0.442943495848729,2.23608325299363E-4,"*",{"v":5.49432e-05,"d":"5.49E-05"},"LAMTOR4","GO:0071986//Ragulator complex","NA","GO:0032008//positive regulation of TOR signaling;GO:0071230//cellular response to amino acid stimulus","K20399//ragulator complex protein LAMTOR4","XP_005413797.1//PREDICTED: ragulator complex protein LAMTOR4 isoform X2 [Chinchilla lanigera];XP_013850875.1//ragulator complex protein LAMTOR4 isoform X6 [Sus scrofa];XP_013364922.1//PREDICTED: ragulator complex protein LAMTOR4 isoform X1 [Chinchilla lanigera]","1//3;3//A2MP1"]
[4282,561,910.76,1237.87,0.442716976234977,{"v":5.51408589565217e-72,"d":"5.51E-72"},"*",{"v":4.76364E-74,"d":"4.76E-74"},"MIF","GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome;GO:0005654//nucleoplasm;GO:0005615//extracellular space;GO:0043209//myelin sheath;GO:0005737//cytoplasm;GO:0031982//vesicle;GO:0009986//cell surface;GO:0005829//cytosol;GO:0005576//extracellular region;GO:1904813//ficolin-1-rich granule lumen","GO:0002020//protease binding;GO:0050178//phenylpyruvate tautomerase activity;GO:0005125//cytokine activity;GO:0042802//identical protein binding;GO:0004167//dopachrome isomerase activity;GO:0005102//receptor binding;GO:0042056//chemoattractant activity;GO:0005126//cytokine receptor binding","GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0010760//negative regulation of macrophage chemotaxis;GO:0043030//regulation of macrophage activation;GO:0007166//cell surface receptor signaling pathway;GO:0030890//positive regulation of B cell proliferation;GO:0032760//positive regulation of tumor necrosis factor production;GO:0071157//negative regulation of cell cycle arrest;GO:0001516//prostaglandin biosynthetic process;GO:0061081//positive regulation of myeloid leukocyte cytokine production involved in immune response;GO:0002906//negative regulation of mature B cell apoptotic process;GO:0045087//innate immune response;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0010739//positive regulation of protein kinase A signaling;GO:0048146//positive regulation of fibroblast proliferation;GO:0043066//negative regulation of apoptotic process;GO:0042327//positive regulation of phosphorylation;GO:1902166//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0061078//positive regulation of prostaglandin secretion involved in immune response;GO:0010629//negative regulation of gene expression;GO:0031666//positive regulation of lipopolysaccharide-mediated signaling pathway;GO:0043518//negative regulation of DNA damage response, signal transduction by p53 class mediator;GO:0008283//cell proliferation;GO:0043312//neutrophil degranulation;GO:0033033//negative regulation of myeloid cell apoptotic process;GO:0070207//protein homotrimerization;GO:0035722//interleukin-12-mediated signaling pathway;GO:0050900//leukocyte migration;GO:0007569//cell aging;GO:0043406//positive regulation of MAP kinase activity;GO:0032269//negative regulation of cellular protein metabolic process;GO:0006954//inflammatory response;GO:0090344//negative regulation of cell aging;GO:0019752//carboxylic acid metabolic process;GO:2000343//positive regulation of chemokine (C-X-C motif) ligand 2 production;GO:0050715//positive regulation of cytokine secretion;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0090238//positive regulation of arachidonic acid secretion","K07253//phenylpyruvate tautomerase [EC:5.3.2.1]","NP_002406.1//macrophage migration inhibitory factor [Homo sapiens]","1//3"]
[130617,1118,14.73,20.02,0.442684543800144,0.00544016151501155,"*",1.769568E-3,"ZFAND2B","GO:0005783//endoplasmic reticulum","GO:0008270//zinc ion binding","GO:0006616//SRP-dependent cotranslational protein targeting to membrane, translocation","K07059//uncharacterized protein","NP_620157.1//AN1-type zinc finger protein 2B isoform 1 [Homo sapiens];XP_011918237.1//PREDICTED: AN1-type zinc finger protein 2B isoform X2 [Cercocebus atys];XP_007964535.1//PREDICTED: AN1-type zinc finger protein 2B isoform X4 [Chlorocebus sabaeus]","1//3;2//1"]
[81894,1584,26.17,35.56,0.442341399781735,{"v":6.10744476712329e-07,"d":"6.11E-07"},"*",{"v":9.7687e-08,"d":"9.77E-08"},"SLC25A28","GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion","GO:0005381//iron ion transmembrane transporter activity","GO:0006810//transport;GO:0048250//mitochondrial iron ion transport;GO:0055072//iron ion homeostasis;GO:0006839//mitochondrial transport","K15113//solute carrier family 25 (mitochondrial iron transporter), member 28/37","AAH47312.1//SLC25A28 protein, partial [Homo sapiens]","3//A2MP1"]
[25864,1118,13.74,18.67,0.442339923408102,4.14151544310787E-3,"*",1.314738E-3,"ABHD14A","GO:0070062//extracellular exosome;GO:0016021//integral component of membrane;GO:0005737//cytoplasm","GO:0016787//hydrolase activity","NA","K13706//abhydrolase domain-containing protein 14","XP_003950172.2//PREDICTED: protein ABHD14A isoform X1 [Pan troglodytes]",4]
[125919,3671,1.31,1.78,0.442310429428948,0.129803917767015,"*",0.0637562,"ZNF543","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","XP_021787176.1//zinc finger protein 805 isoform X1 [Papio anubis]","3//A2MP1"]
[23550,5039,2.76,3.75,0.442222328605074,0.00566012373210516,"*",0.001846432,"PSD4","NA","NA","NA","K12494//PH and SEC7 domain-containing protein","XP_016804757.1//PREDICTED: PH and SEC7 domain-containing protein 4 isoform X1 [Pan troglodytes]","2//1"]
[4728,824,193.73,263.2,0.442112109732235,{"v":1.57847133202614e-23,"d":"1.58E-23"},"*",{"v":6.04748e-25,"d":"6.05E-25"},"NDUFS8","GO:0016020//membrane;GO:0005759//mitochondrial matrix;GO:0005747//mitochondrial respiratory chain complex I;GO:0005739//mitochondrion","GO:0016651//oxidoreductase activity, acting on NAD(P)H;GO:0046872//metal ion binding;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0008137//NADH dehydrogenase (ubiquinone) activity","GO:0006979//response to oxidative stress;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0006120//mitochondrial electron transport, NADH to ubiquinone","K03941//NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:1.6.5.3 1.6.99.3]","NP_002487.1//NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial precursor [Homo sapiens]","3//A2MP1"]
[728441,2583,3.35,4.55,0.441705449740924,0.0347636810871253,"*",0.01401298,"GGT2","NA","NA","NA","K18592//gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]","NP_001338233.1//inactive gamma-glutamyltranspeptidase 2 precursor [Homo sapiens]","1//3"]
[124944,893,79.82,108.36,0.441010114690743,{"v":5.29232038895282e-10,"d":"5.29E-10"},"*",{"v":5.75814e-11,"d":"5.76E-11"},"C17orf49","GO:0005654//nucleoplasm;GO:0071339//MLL1 complex;GO:0016589//NURF complex;GO:0005829//cytosol","GO:0003677//DNA binding","GO:0016569//covalent chromatin modification","NA","XP_017387237.1//PREDICTED: chromatin complexes subunit BAP18 isoform X4 [Cebus capucinus imitator];XP_012632717.1//chromatin complexes subunit BAP18 isoform X1 [Microcebus murinus];XP_017387234.1//PREDICTED: chromatin complexes subunit BAP18 isoform X1 [Cebus capucinus imitator]","3//A2MP1;2//1"]
[390,2749,13.09,17.77,0.440978584083437,{"v":5.03863447169811e-06,"d":"5.04E-06"},"*",{"v":9.36188e-07,"d":"9.36E-07"},"RND3","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005925//focal adhesion;GO:0005622//intracellular;GO:0005886//plasma membrane;GO:0000139//Golgi membrane","GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0007155//cell adhesion;GO:0030036//actin cytoskeleton organization;GO:0007264//small GTPase mediated signal transduction","K07859//Rho family GTPase 3","NP_005159.1//rho-related GTP-binding protein RhoE precursor [Homo sapiens]","4;1//3"]
[440712,1684,0.14,0.19,0.440572591385981,0.782591323521006,"*",0.685686,"RHEX","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","NA","NA","NA","NP_001007545.1//uncharacterized protein C1orf186 [Homo sapiens]","3//A2MP1"]
[1909,2132,0.14,0.19,0.440572591385981,0.734684326992288,"*",0.626188,"EDNRA","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004435//phosphatidylinositol phospholipase C activity;GO:0004962//endothelin receptor activity","GO:0008217//regulation of blood pressure;GO:0042310//vasoconstriction;GO:0008283//cell proliferation;GO:0030818//negative regulation of cAMP biosynthetic process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0014032//neural crest cell development;GO:0007585//respiratory gaseous exchange;GO:0007165//signal transduction;GO:0007507//heart development;GO:0006939//smooth muscle contraction;GO:0001701//in utero embryonic development;GO:0001666//response to hypoxia;GO:0015758//glucose transport;GO:0048484//enteric nervous system development;GO:0007190//activation of adenylate cyclase activity;GO:0060322//head development;GO:0007202//activation of phospholipase C activity;GO:0014824//artery smooth muscle contraction;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0001569//branching involved in blood vessel morphogenesis","K04197//endothelin receptor type A","NP_001341726.1//endothelin-1 receptor isoform d precursor [Homo sapiens];NP_001159527.1//endothelin-1 receptor isoform b precursor [Homo sapiens];NP_001948.1//endothelin-1 receptor isoform a precursor [Homo sapiens]","1//3;3//A2MP1"]
[23237,2948,0.14,0.19,0.440572591385981,0.695740145126082,"*",0.578622,"ARC","GO:0030054//cell junction;GO:0001669//acrosomal vesicle;GO:0014069//postsynaptic density;GO:0005737//cytoplasm;GO:0043025//neuronal cell body;GO:0005768//endosome;GO:0015629//actin cytoskeleton;GO:0043197//dendritic spine;GO:0005886//plasma membrane;GO:0045211//postsynaptic membrane","NA","GO:0007492//endoderm development;GO:0009952//anterior/posterior pattern specification;GO:1900271//regulation of long-term synaptic potentiation;GO:0016477//cell migration;GO:0061001//regulation of dendritic spine morphogenesis;GO:0007612//learning;GO:2000969//positive regulation of AMPA receptor activity;GO:0007616//long-term memory;GO:0060997//dendritic spine morphogenesis;GO:0048168//regulation of neuronal synaptic plasticity;GO:0060291//long-term synaptic potentiation;GO:0007010//cytoskeleton organization;GO:0006897//endocytosis;GO:0022604//regulation of cell morphogenesis","K15867//activity-regulated cytoskeleton-associated protein","NP_056008.1//activity-regulated cytoskeleton-associated protein [Homo sapiens]",4]
[448831,2084,0.28,0.38,0.440572591385981,0.734360701270098,"*",0.626188,"FRG2","GO:0005634//nucleus","NA","NA","K22069//LYR motif-containing protein 4;K11447//histone demethylase [EC:1.14.11.-];K15696//RING finger protein 113B;K17985//activating molecule in BECN1-regulated autophagy protein 1;K18047//serine/threonine/tyrosine-interacting-like protein 1","NP_001005217.1//protein FRG2 isoform 2 [Homo sapiens];NP_001273749.1//protein FRG2 isoform 1 [Homo sapiens]","1//3"]
[55824,10759,0.14,0.19,0.440572591385981,0.434347554423694,"*",0.288278,"PAG1","GO:0045121//membrane raft;GO:0005887//integral component of plasma membrane;GO:0005622//intracellular;GO:0005886//plasma membrane","GO:0005070//SH3/SH2 adaptor activity;GO:0005068//transmembrane receptor protein tyrosine kinase adaptor activity;GO:0042169//SH2 domain binding","GO:0050863//regulation of T cell activation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007165//signal transduction;GO:0050852//T cell receptor signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0050868//negative regulation of T cell activation;GO:0035556//intracellular signal transduction;GO:0002250//adaptive immune response","K12581//CCR4-NOT transcription complex subunit 7/8;K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K15696//RING finger protein 113B;K17985//activating molecule in BECN1-regulated autophagy protein 1","NP_060910.3//phosphoprotein associated with glycosphingolipid-enriched microdomains 1 [Homo sapiens]","3//A2MP1"]
[5002,1492,21.86,29.66,0.440225196782726,{"v":4.960284967171e-05,"d":"4.96E-05"},"*",{"v":1.08776e-05,"d":"1.09E-05"},"SLC22A18","GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0005635//nuclear envelope;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0015307//drug:proton antiporter activity;GO:0031625//ubiquitin protein ligase binding;GO:0015238//drug transmembrane transporter activity;GO:0015293//symporter activity;GO:0005215//transporter activity","GO:0015695//organic cation transport;GO:0055085//transmembrane transport;GO:0015893//drug transport;GO:0007588//excretion","K08214//MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 18","NP_001302431.1//solute carrier family 22 member 18 isoform c [Homo sapiens];NP_001302430.1//solute carrier family 22 member 18 isoform a [Homo sapiens]","1//3;2//1;5"]
[8721,748,180.77,245.23,0.439980208024017,{"v":6.71454580240964e-19,"d":"6.71E-19"},"*",{"v":3.48884e-20,"d":"3.49E-20"},"EDF1","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005737//cytoplasm;GO:0005669//transcription factor TFIID complex","GO:0003723//RNA binding;GO:0003713//transcription coactivator activity;GO:0043565//sequence-specific DNA binding;GO:0005516//calmodulin binding","GO:0030154//cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0007275//multicellular organism development;GO:0045446//endothelial cell differentiation;GO:0019216//regulation of lipid metabolic process;GO:0043388//positive regulation of DNA binding","K03627//putative transcription factor","XP_003480683.2//endothelial differentiation-related factor 1 [Sus scrofa];NP_001268226.1//endothelial differentiation-related factor 1 isoform 3 [Homo sapiens];XP_012364470.1//PREDICTED: endothelial differentiation-related factor 1 isoform X1 [Nomascus leucogenys]","1//3;3//A2MP1;2//1"]
[3163,1789,28.79,39.05,0.439754759465907,{"v":4.43562319777159e-07,"d":"4.44E-07"},"*",{"v":6.97804e-08,"d":"6.98E-08"},"HMOX2","GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane","GO:0046872//metal ion binding;GO:0020037//heme binding;GO:0004392//heme oxygenase (decyclizing) activity","GO:0006979//response to oxidative stress;GO:0042167//heme catabolic process;GO:0006879//cellular iron ion homeostasis;GO:0055072//iron ion homeostasis;GO:0006788//heme oxidation;GO:0043312//neutrophil degranulation;GO:0001666//response to hypoxia","K21418//heme oxygenase 2 [EC:1.14.14.18]","NP_002125.3//heme oxygenase 2 isoform b [Homo sapiens];NP_001273196.1//heme oxygenase 2 isoform a [Homo sapiens];XP_009428495.1//PREDICTED: heme oxygenase 2 isoform X1 [Pan troglodytes];XP_008966249.2//PREDICTED: heme oxygenase 2 isoform X1 [Pan paniscus]","1//3;3//A2MP1;2//1"]
[51149,1133,44.99,61.02,0.43967781299961,{"v":1.65050257420719e-07,"d":"1.65E-07"},"*",{"v":2.44362e-08,"d":"2.44E-08"},"MRNIP","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0030870//Mre11 complex","GO:0003682//chromatin binding","GO:0010212//response to ionizing radiation;GO:0071168//protein localization to chromatin;GO:0007095//mitotic G2 DNA damage checkpoint;GO:0006281//DNA repair;GO:2001032//regulation of double-strand break repair via nonhomologous end joining;GO:1905168//positive regulation of double-strand break repair via homologous recombination;GO:0045860//positive regulation of protein kinase activity;GO:0006974//cellular response to DNA damage stimulus","NA","NP_057259.2//MRN complex-interacting protein isoform 1 [Homo sapiens];NP_001017987.1//MRN complex-interacting protein isoform 2 [Homo sapiens]","3//A2MP1;2//1"]
[130612,2362,0.73,0.99,0.439532061199592,0.410754757036186,"*",0.268608,"TMEM198","GO:0031410//cytoplasmic vesicle;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","NA","GO:0007275//multicellular organism development;GO:0016055//Wnt signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway","K16628//collagen, type VII, alpha;K17501//protein phosphatase 1E [EC:3.1.3.16];K00747//chondroitin polymerizing factor [EC:2.4.1.175 2.4.1.226]","XP_001494200.3//PREDICTED: transmembrane protein 198 isoform X1 [Equus caballus];NP_001005209.1//transmembrane protein 198 [Homo sapiens]","1//3;2//1"]
[150678,456,36.75,49.83,0.439270324072443,0.00394168491071075,"*",0.001246366,"COPS9","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0008180//COP9 signalosome;GO:0000790//nuclear chromatin;GO:0005737//cytoplasm","NA","GO:0051220//cytoplasmic sequestering of protein;GO:0034644//cellular response to UV;GO:2000435//negative regulation of protein neddylation;GO:0008284//positive regulation of cell proliferation","NA","XP_008963886.1//PREDICTED: myeloma-overexpressed gene 2 protein isoform X2 [Pan paniscus];NP_612209.1//COP9 signalosome complex subunit 9 isoform 1 [Homo sapiens]","1//3"]
[11094,2687,3.43,4.65,0.439022139822581,0.0204730688659794,"*",0.00770784,"CACFD1","GO:0016021//integral component of membrane","NA","GO:0016192//vesicle-mediated transport","K08627//a disintegrin and metalloproteinase with thrombospondin motifs 13 [EC:3.4.24.87];K22125//myoferlin","XP_018888693.1//PREDICTED: uncharacterized protein LOC109028208 [Gorilla gorilla gorilla];XP_008003971.1//PREDICTED: calcium channel flower homolog isoform X3 [Chlorocebus sabaeus];XP_012300572.1//calcium channel flower homolog [Aotus nancymaae]","1//3;3//A2MP1;2//1"]
[5554,1052,3.38,4.58,0.43832435181476,0.330796817342366,"*",0.1986976,"PRH1","NA","NA","NA","K13910//salivary acidic proline-rich phosphoprotein 1/2","XP_018894118.1//PREDICTED: salivary acidic proline-rich phosphoprotein 1/2 [Gorilla gorilla gorilla];NP_001278244.1//salivary acidic proline-rich phosphoprotein 1/2 isoform b [Homo sapiens]","1//3"]
[26093,2093,10.01,13.56,0.43791520430035,0.000592873661350844,"*",0.000158258,"CCDC9","NA","NA","NA","K22020//mucin-19;K19607//X-linked retinitis pigmentosa GTPase regulator","XP_008965001.1//PREDICTED: coiled-coil domain-containing protein 9 isoform X3 [Pan paniscus]","2//1"]
[10400,953,61.45,83.24,0.437863954475311,{"v":1.42777434951644E-8,"d":"1.43E-08"},"*",{"v":1.848402E-9,"d":"1.85E-09"},"PEMT","GO:0031526//brush border membrane;GO:0042383//sarcolemma;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0005789//endoplasmic reticulum membrane","GO:0004608//phosphatidylethanolamine N-methyltransferase activity;GO:0080101//phosphatidyl-N-dimethylethanolamine N-methyltransferase activity;GO:0008429//phosphatidylethanolamine binding;GO:0000773//phosphatidyl-N-methylethanolamine N-methyltransferase activity","GO:0042493//response to drug;GO:0043200//response to amino acid;GO:0046498//S-adenosylhomocysteine metabolic process;GO:1903955//positive regulation of protein targeting to mitochondrion;GO:0046500//S-adenosylmethionine metabolic process;GO:0006686//sphingomyelin biosynthetic process;GO:0045471//response to ethanol;GO:0008283//cell proliferation;GO:0050747//positive regulation of lipoprotein metabolic process;GO:0033273//response to vitamin;GO:0006656//phosphatidylcholine biosynthetic process;GO:0006629//lipid metabolic process;GO:0008285//negative regulation of cell proliferation","K00551//phosphatidylethanolamine N-methyltransferase [EC:2.1.1.17]","NP_001254481.1//phosphatidylethanolamine N-methyltransferase isoform 3 [Homo sapiens];NP_680477.1//phosphatidylethanolamine N-methyltransferase isoform 1 [Homo sapiens];NP_001254480.1//phosphatidylethanolamine N-methyltransferase isoform 4 [Homo sapiens]","1//3;2//1"]
[114789,3372,5.36,7.26,0.437736547537978,2.04728837305263E-3,"*",0.000608778,"SLC25A25","GO:0070062//extracellular exosome;GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion","GO:0005347//ATP transmembrane transporter activity;GO:0015217//ADP transmembrane transporter activity;GO:0005509//calcium ion binding","GO:0070588//calcium ion transmembrane transport;GO:0046034//ATP metabolic process;GO:0055085//transmembrane transport;GO:0043010//camera-type eye development;GO:0014823//response to activity;GO:0032094//response to food;GO:0002021//response to dietary excess;GO:0060612//adipose tissue development;GO:0006839//mitochondrial transport;GO:0035264//multicellular organism growth;GO:0045333//cellular respiration","K14684//solute carrier family 25 (mitochondrial phosphate transporter), member 23/24/25/41","XP_001362766.1//PREDICTED: calcium-binding mitochondrial carrier protein SCaMC-2 isoform X1 [Monodelphis domestica];XP_005908520.1//PREDICTED: calcium-binding mitochondrial carrier protein SCaMC-2 isoform X3 [Bos mutus];XP_003407751.1//PREDICTED: calcium-binding mitochondrial carrier protein SCaMC-2 isoform X1 [Loxodonta africana];XP_011362527.1//PREDICTED: calcium-binding mitochondrial carrier protein SCaMC-2 isoform X2 [Pteropus vampyrus];XP_011362528.1//PREDICTED: calcium-binding mitochondrial carrier protein SCaMC-2 isoform X3 [Pteropus vampyrus]","4;1//3;3//A2MP1;2//1"]
[2531,5198,7.99,10.82,0.437433090898838,{"v":6.07332355973365e-07,"d":"6.07E-07"},"*",{"v":9.70652E-8,"d":"9.71E-08"},"KDSR","GO:0016020//membrane;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0047560//3-dehydrosphinganine reductase activity;GO:0016491//oxidoreductase activity","GO:0030148//sphingolipid biosynthetic process;GO:0006666//3-keto-sphinganine metabolic process","K04708//3-dehydrosphinganine reductase [EC:1.1.1.102]","NP_002026.1//3-ketodihydrosphingosine reductase precursor [Homo sapiens]","2//1"]
[4162,3332,1.84,2.49,0.436439976011068,0.0796771950610433,"*",0.035953,"MCAM","GO:0005634//nucleus;GO:0005615//extracellular space;GO:0005925//focal adhesion;GO:0009897//external side of plasma membrane;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane","NA","GO:0061042//vascular wound healing;GO:0007155//cell adhesion;GO:0009653//anatomical structure morphogenesis;GO:0030335//positive regulation of cell migration;GO:0003094//glomerular filtration;GO:0001525//angiogenesis","K06534//melanoma cell adhesion molecule","BAD93162.1//Melanoma cell adhesion molecule variant, partial [Homo sapiens]","2//1"]
[157807,3506,12.57,17.01,0.436398491242877,{"v":2.995614e-07,"d":"3.00E-07"},"*",{"v":4.5945e-08,"d":"4.59E-08"},"CLVS1","GO:0005768//endosome;GO:0032588//trans-Golgi network membrane;GO:0031901//early endosome membrane;GO:0030136//clathrin-coated vesicle;GO:0005802//trans-Golgi network;GO:0030669//clathrin-coated endocytic vesicle membrane","GO:0080025//phosphatidylinositol-3,5-bisphosphate binding;GO:0005215//transporter activity","GO:0007040//lysosome organization","K19625//retinaldehyde-binding protein 1","NP_775790.1//clavesin-1 [Homo sapiens]","2//1"]
[23309,5061,8.72,11.8,0.436386819472277,{"v":5.65749402144772e-06,"d":"5.66E-06"},"*",{"v":1.05684E-6,"d":"1.06E-06"},"SIN3B","GO:0030849//autosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000805//X chromosome;GO:0016580//Sin3 complex;GO:0001741//XY body;GO:0005737//cytoplasm;GO:0000806//Y chromosome","GO:0001106//RNA polymerase II transcription corepressor activity;GO:0003714//transcription corepressor activity;GO:0003682//chromatin binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006355//regulation of transcription, DNA-templated;GO:0019216//regulation of lipid metabolic process;GO:0006351//transcription, DNA-templated;GO:0016575//histone deacetylation","K11644//paired amphipathic helix protein Sin3a","NP_001284524.1//paired amphipathic helix protein Sin3b isoform 2 [Homo sapiens];NP_056075.1//paired amphipathic helix protein Sin3b isoform 1 [Homo sapiens];XP_018871745.1//PREDICTED: paired amphipathic helix protein Sin3b [Gorilla gorilla gorilla]","1//3;3//A2MP1"]
[1545,5160,25.33,34.27,0.436099114806674,{"v":7.62672486153846e-20,"d":"7.63E-20"},"*",{"v":3.72408e-21,"d":"3.72E-21"},"CYP1B1","GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0005739//mitochondrion;GO:0005789//endoplasmic reticulum membrane","GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0020037//heme binding;GO:0005506//iron ion binding;GO:0070330//aromatase activity;GO:0004497//monooxygenase activity;GO:0019825//oxygen binding;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen","GO:0019369//arachidonic acid metabolic process;GO:0061304//retinal blood vessel morphogenesis;GO:0030199//collagen fibril organization;GO:0006725//cellular aromatic compound metabolic process;GO:0007601//visual perception;GO:0071603//endothelial cell-cell adhesion;GO:0043065//positive regulation of apoptotic process;GO:0016125//sterol metabolic process;GO:0045766//positive regulation of angiogenesis;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0008285//negative regulation of cell proliferation;GO:0070301//cellular response to hydrogen peroxide;GO:0001525//angiogenesis;GO:0043542//endothelial cell migration;GO:0002930//trabecular meshwork development;GO:0006805//xenobiotic metabolic process;GO:0007155//cell adhesion;GO:0048514//blood vessel morphogenesis;GO:0008210//estrogen metabolic process;GO:0046466//membrane lipid catabolic process;GO:0009404//toxin metabolic process;GO:0010575//positive regulation of vascular endothelial growth factor production;GO:0042574//retinal metabolic process;GO:0055114//oxidation-reduction process;GO:0009636//response to toxic substance;GO:0046427//positive regulation of JAK-STAT cascade;GO:0008202//steroid metabolic process;GO:0071407//cellular response to organic cyclic compound;GO:0097267//omega-hydroxylase P450 pathway;GO:0019373//epoxygenase P450 pathway;GO:0033629//negative regulation of cell adhesion mediated by integrin;GO:0008631//intrinsic apoptotic signaling pathway in response to oxidative stress;GO:0042572//retinol metabolic process;GO:0030336//negative regulation of cell migration;GO:2000377//regulation of reactive oxygen species metabolic process;GO:0006809//nitric oxide biosynthetic process","K07410//cytochrome P450 family 1 subfamily B polypeptide 1 [EC:1.14.14.1]","NP_000095.2//cytochrome P450 1B1 [Homo sapiens]","3//A2MP1"]
[151306,1627,0.17,0.23,0.436099114806673,0.831130183882581,"*",0.751524,"GPBAR1","GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0038181//bile acid receptor activity;GO:0038182//G-protein coupled bile acid receptor activity;GO:0004930//G-protein coupled receptor activity","GO:2000810//regulation of bicellular tight junction assembly;GO:0038184//cell surface bile acid receptor signaling pathway","K08400//G protein-coupled bile acid receptor 1","XP_003907996.2//G-protein coupled bile acid receptor 1 isoform X1 [Papio anubis];XP_007964435.1//PREDICTED: G-protein coupled bile acid receptor 1 isoform X2 [Chlorocebus sabaeus]","1//3;2//1"]
[10610,2105,0.34,0.46,0.436099114806673,0.641333181425486,"*",0.520486,"ST6GALNAC2","GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0008373//sialyltransferase activity;GO:0001665//alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity","GO:0006486//protein glycosylation;GO:0018279//protein N-linked glycosylation via asparagine;GO:0009311//oligosaccharide metabolic process;GO:0097503//sialylation;GO:0016266//O-glycan processing","K06616//alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase (sialyltransferase 7B) [EC:2.4.99.-]","NP_006447.2//alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 precursor [Homo sapiens]","2//1"]
[2852,2693,0.17,0.23,0.436099114806673,0.718408161868631,"*",0.60458,"GPER1","GO:0030424//axon;GO:0005783//endoplasmic reticulum;GO:0005635//nuclear envelope;GO:0030054//cell junction;GO:0005802//trans-Golgi network;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0016021//integral component of membrane;GO:0045095//keratin filament;GO:0043679//axon terminus;GO:0055037//recycling endosome;GO:0005886//plasma membrane;GO:0005769//early endosome;GO:0030659//cytoplasmic vesicle membrane","GO:0030284//estrogen receptor activity;GO:0003682//chromatin binding;GO:0017082//mineralocorticoid receptor activity;GO:1990239//steroid hormone binding;GO:0004930//G-protein coupled receptor activity","GO:0030335//positive regulation of cell migration;GO:0071356//cellular response to tumor necrosis factor;GO:0050728//negative regulation of inflammatory response;GO:1903078//positive regulation of protein localization to plasma membrane;GO:0045742//positive regulation of epidermal growth factor receptor signaling pathway;GO:0071157//negative regulation of cell cycle arrest;GO:0051898//negative regulation of protein kinase B signaling;GO:0030819//positive regulation of cAMP biosynthetic process;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0045599//negative regulation of fat cell differentiation;GO:0071375//cellular response to peptide hormone stimulus;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0071333//cellular response to glucose stimulus;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0032962//positive regulation of inositol trisphosphate biosynthetic process;GO:0002695//negative regulation of leukocyte activation;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0051055//negative regulation of lipid biosynthetic process;GO:0032024//positive regulation of insulin secretion;GO:0010629//negative regulation of gene expression;GO:1904706//negative regulation of vascular smooth muscle cell proliferation;GO:0070474//positive regulation of uterine smooth muscle contraction;GO:2000724//positive regulation of cardiac vascular smooth muscle cell differentiation;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0045745//positive regulation of G-protein coupled receptor protein signaling pathway;GO:0050769//positive regulation of neurogenesis;GO:0030263//apoptotic chromosome condensation;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0007049//cell cycle;GO:0071392//cellular response to estradiol stimulus;GO:0008284//positive regulation of cell proliferation","K04246//G protein-coupled receptor 30","NP_001496.1//G-protein coupled estrogen receptor 1 [Homo sapiens]","1//3;2//1"]
[26240,1673,2.07,2.8,0.435796059445641,0.239951739437249,"*",0.1345316,"FAM50B","GO:0045171//intercellular bridge;GO:0005634//nucleus;GO:0005654//nucleoplasm","NA","NA","K13119//protein FAM50","NP_036267.1//protein FAM50B [Homo sapiens]","2//1"]
[57194,5235,1.9,2.57,0.43576894086293,0.025962641053482,"*",0.01005902,"ATP10A","GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane","GO:0000287//magnesium ion binding;GO:0005524//ATP binding;GO:0004012//phospholipid-translocating ATPase activity","GO:0045332//phospholipid translocation;GO:0034220//ion transmembrane transport;GO:0008360//regulation of cell shape","K01530//phospholipid-translocating ATPase [EC:3.6.3.1]","NP_077816.1//probable phospholipid-transporting ATPase VA [Homo sapiens]","3//A2MP1"]
[50512,2209,7.8,10.55,0.435696969844937,0.00222333007054895,"*",0.000666832,"PODXL2","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005796//Golgi lumen","GO:0005539//glycosaminoglycan binding","GO:0050901//leukocyte tethering or rolling;GO:0050427//3'-phosphoadenosine 5'-phosphosulfate metabolic process","K06818//podocalyxin-like 2","NP_056535.1//podocalyxin-like protein 2 precursor [Homo sapiens]","3//A2MP1"]
[55520,2233,1.22,1.65,0.43558487668293,0.304487917685845,"*",0.179235,"ELAC1","GO:0005634//nucleus;GO:0005829//cytosol","GO:0046872//metal ion binding;GO:0016891//endoribonuclease activity, producing 5'-phosphomonoesters;GO:0042781//3'-tRNA processing endoribonuclease activity","GO:0042779//tRNA 3'-trailer cleavage","K00784//ribonuclease Z [EC:3.1.26.11]","NP_061166.1//zinc phosphodiesterase ELAC protein 1 [Homo sapiens]","2//1"]
[730098,1532,3.01,4.07,0.435265307506545,0.161158916290971,"*",0.082799,"LOC730098","NA","NA","NA","K16598//C-C motif chemokine 27","AAH37171.1//Unknown (protein for IMAGE:5248278), partial [Homo sapiens];XP_010384105.1//PREDICTED: uncharacterized protein LOC104680017 [Rhinopithecus roxellana]","1//3"]
[6231,1203,346.99,469.18,0.43524743012495,{"v":1.05940644898876e-59,"d":"1.06E-59"},"*",{"v":1.180508e-61,"d":"1.18E-61"},"RPS26","NA","NA","NA","K02976//small subunit ribosomal protein S26e","XP_005335675.1//40S ribosomal protein S26 [Ictidomys tridecemlineatus]",4]
[84876,1496,43.62,58.98,0.435236052420986,{"v":4.53445885913853E-10,"d":"4.53E-10"},"*",{"v":4.8768e-11,"d":"4.88E-11"},"ORAI1","GO:0016323//basolateral plasma membrane;GO:0016020//membrane;GO:0005887//integral component of plasma membrane;GO:0043234//protein complex;GO:0016021//integral component of membrane","GO:0015279//store-operated calcium channel activity;GO:0042802//identical protein binding;GO:0005516//calmodulin binding","GO:0061180//mammary gland epithelium development;GO:0051924//regulation of calcium ion transport;GO:0070509//calcium ion import;GO:0002115//store-operated calcium entry;GO:0051928//positive regulation of calcium ion transport;GO:0002250//adaptive immune response","K16056//calcium release-activated calcium channel protein 1","NP_116179.2//calcium release-activated calcium channel protein 1 [Homo sapiens]","3//A2MP1"]
[100293516,3356,4.09,5.53,0.435178637292958,0.00684407324538259,"*",0.00227336,"ZNF587B","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_011835096.1//PREDICTED: LOW QUALITY PROTEIN: putative uncharacterized zinc finger protein 814 [Mandrillus leucophaeus]","1//3"]
[7769,2269,5.2,7.03,0.435013066044081,0.331412930612245,"*",0.1992544,"ZNF226","GO:0005634//nucleus;GO:0005622//intracellular","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","NP_001027544.1//zinc finger protein 226 isoform a [Homo sapiens];XP_004091064.1//PREDICTED: zinc finger protein 226 isoform X3 [Nomascus leucogenys]","1//3;3//A2MP1;2//1"]
[9533,1309,22.88,30.93,0.434919781310875,{"v":5.86256169799605e-05,"d":"5.86E-05"},"*",{"v":1.300304E-5,"d":"1.30E-05"},"POLR1C","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005666//DNA-directed RNA polymerase III complex;GO:0005736//DNA-directed RNA polymerase I complex","GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0003677//DNA binding;GO:0046983//protein dimerization activity","GO:0006363//termination of RNA polymerase I transcription;GO:0006362//transcription elongation from RNA polymerase I promoter;GO:0032481//positive regulation of type I interferon production;GO:0045815//positive regulation of gene expression, epigenetic;GO:0006361//transcription initiation from RNA polymerase I promoter;GO:0006360//transcription from RNA polymerase I promoter;GO:0006351//transcription, DNA-templated;GO:0006383//transcription from RNA polymerase III promoter","K03027//DNA-directed RNA polymerases I and III subunit RPAC1","NP_001305805.1//DNA-directed RNA polymerases I and III subunit RPAC1 isoform 2 [Homo sapiens];XP_007970669.1//PREDICTED: DNA-directed RNA polymerases I and III subunit RPAC1 [Chlorocebus sabaeus]","1//3;3//A2MP1"]
[29095,1361,29.85,40.35,0.434837742012975,{"v":1.36488758564558e-06,"d":"1.36E-06"},"*",{"v":2.30956e-07,"d":"2.31E-07"},"ORMDL2","GO:0035339//SPOTS complex;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane","NA","GO:0090156//cellular sphingolipid homeostasis;GO:1900060//negative regulation of ceramide biosynthetic process;GO:0006672//ceramide metabolic process","NA","XP_010348246.1//PREDICTED: ORM1-like protein 2 [Saimiri boliviensis boliviensis]",4]
[7031,508,2.9,3.92,0.434800754100274,0.498836129719964,"*",0.345694,"TFF1","GO:0005615//extracellular space","GO:0008083//growth factor activity","GO:0030154//cell differentiation;GO:0007586//digestion;GO:0042060//wound healing;GO:0043434//response to peptide hormone;GO:0010039//response to iron ion;GO:0035902//response to immobilization stress;GO:0005975//carbohydrate metabolic process;GO:0030277//maintenance of gastrointestinal epithelium;GO:0008285//negative regulation of cell proliferation","K01176//alpha-amylase [EC:3.2.1.1];K05641//ATP-binding cassette, subfamily A (ABC1), member 1","XP_003280716.1//PREDICTED: trefoil factor 1 [Nomascus leucogenys]","2//1"]
[7133,3682,0.37,0.5,0.434402824145775,0.498881195771976,"*",0.345694,"TNFRSF1B","GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0043025//neuronal cell body;GO:0043196//varicosity;GO:0005887//integral component of plasma membrane;GO:0045121//membrane raft;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0035579//specific granule membrane;GO:0005886//plasma membrane","GO:0031625//ubiquitin protein ligase binding;GO:0005031//tumor necrosis factor-activated receptor activity","GO:0050779//RNA destabilization;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0097191//extrinsic apoptotic signaling pathway;GO:0097190//apoptotic signaling pathway;GO:0042127//regulation of cell proliferation;GO:0051044//positive regulation of membrane protein ectodomain proteolysis;GO:0071222//cellular response to lipopolysaccharide;GO:0050728//negative regulation of inflammatory response;GO:0006954//inflammatory response;GO:0007568//aging;GO:0071363//cellular response to growth factor stimulus;GO:0007275//multicellular organism development;GO:0043312//neutrophil degranulation;GO:0006955//immune response;GO:0033209//tumor necrosis factor-mediated signaling pathway","K05141//tumor necrosis factor receptor superfamily member 1B","NP_001057.1//tumor necrosis factor receptor superfamily member 1B precursor [Homo sapiens]","2//1"]
[3111,3485,0.37,0.5,0.434402824145775,0.570554698741162,"*",0.414254,"HLA-DOA","GO:0005765//lysosomal membrane;GO:0010008//endosome membrane;GO:0042613//MHC class II protein complex;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0032395//MHC class II receptor activity;GO:0023026//MHC class II protein complex binding","GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0006955//immune response;GO:0045580//regulation of T cell differentiation;GO:0002587//negative regulation of antigen processing and presentation of peptide antigen via MHC class II","K06752//major histocompatibility complex, class II","NP_002110.1//HLA class II histocompatibility antigen, DO alpha chain precursor [Homo sapiens]","3//A2MP1"]
[2131,3376,19.87,26.85,0.434330215623105,{"v":1.77237958560976E-10,"d":"1.77E-10"},"*",{"v":1.819646e-11,"d":"1.82E-11"},"EXT1","GO:0005783//endoplasmic reticulum;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0000139//Golgi membrane","GO:0008375//acetylglucosaminyltransferase activity;GO:0046872//metal ion binding;GO:0042328//heparan sulfate N-acetylglucosaminyltransferase activity;GO:0016757//transferase activity, transferring glycosyl groups;GO:0046982//protein heterodimerization activity;GO:0015020//glucuronosyltransferase activity;GO:0050508//glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity;GO:0042803//protein homodimerization activity;GO:0050509//N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity","GO:0007498//mesoderm development;GO:0007369//gastrulation;GO:0007492//endoderm development;GO:0006486//protein glycosylation;GO:0007165//signal transduction;GO:0015014//heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process;GO:0001503//ossification;GO:0021772//olfactory bulb development;GO:0006024//glycosaminoglycan biosynthetic process;GO:0072498//embryonic skeletal joint development;GO:0033692//cellular polysaccharide biosynthetic process;GO:0015012//heparan sulfate proteoglycan biosynthetic process;GO:0001501//skeletal system development;GO:0007411//axon guidance","K02366//glucuronyl/N-acetylglucosaminyl transferase EXT1 [EC:2.4.1.224 2.4.1.225]","NP_000118.2//exostosin-1 [Homo sapiens]","2//1"]
[29115,2759,21.58,29.16,0.43429585483892,{"v":4.90012710791367E-9,"d":"4.90E-09"},"*",{"v":5.96948e-10,"d":"5.97E-10"},"SAP30BP","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0045111//intermediate filament cytoskeleton","NA","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0010942//positive regulation of cell death;GO:0006915//apoptotic process","K19607//X-linked retinitis pigmentosa GTPase regulator","NP_001288784.1//SAP30-binding protein isoform 1 [Homo sapiens];XP_012893425.1//PREDICTED: SAP30-binding protein [Dipodomys ordii]","1//3;7"]
[4696,414,181.96,245.85,0.434157015416323,{"v":1.68946886018349e-10,"d":"1.69E-10"},"*",{"v":1.729236e-11,"d":"1.73E-11"},"NDUFA3","GO:0005747//mitochondrial respiratory chain complex I;GO:0016021//integral component of membrane","NA","NA","K03947//NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 3","XP_010378998.1//PREDICTED: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 isoform X2 [Rhinopithecus roxellana]","3//A2MP1"]
[10516,2637,0.94,1.27,0.434095835094529,0.329438886932944,"*",0.1977582,"FBLN5","GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0071953//elastic fiber;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix","GO:0008022//protein C-terminus binding;GO:0005178//integrin binding;GO:0005509//calcium ion binding;GO:0042803//protein homodimerization activity","GO:0001558//regulation of cell growth;GO:0007160//cell-matrix adhesion;GO:2000121//regulation of removal of superoxide radicals;GO:0030198//extracellular matrix organization;GO:0048251//elastic fiber assembly;GO:0046903//secretion;GO:0034394//protein localization to cell surface","K17340//fibulin 5","EHH28115.1//hypothetical protein EGK_18468, partial [Macaca mulatta]","3//A2MP1"]
[23746,2801,0.97,1.31,0.433510159350323,0.358990868362157,"*",0.220914,"AIPL1","GO:0005634//nucleus;GO:0001917//photoreceptor inner segment;GO:0005737//cytoplasm","GO:0001918//farnesylated protein binding;GO:0051082//unfolded protein binding","GO:0007603//phototransduction, visible light;GO:0001895//retina homeostasis;GO:0007601//visual perception;GO:0043066//negative regulation of apoptotic process;GO:0030823//regulation of cGMP metabolic process;GO:0018343//protein farnesylation","K17767//AH receptor-interacting protein","XP_011850056.1//PREDICTED: aryl-hydrocarbon-interacting protein-like 1 isoform X6 [Mandrillus leucophaeus];NP_001028226.1//aryl-hydrocarbon-interacting protein-like 1 isoform 2 [Homo sapiens];NP_001272329.1//aryl-hydrocarbon-interacting protein-like 1 isoform 5 [Homo sapiens];NP_001272328.1//aryl-hydrocarbon-interacting protein-like 1 isoform 4 [Homo sapiens];NP_001028227.1//aryl-hydrocarbon-interacting protein-like 1 isoform 3 [Homo sapiens];NP_055151.3//aryl-hydrocarbon-interacting protein-like 1 isoform 1 [Homo sapiens];NP_001272330.1//aryl-hydrocarbon-interacting protein-like 1 isoform 6 [Homo sapiens]","4;1//3;2//1"]
[79639,2287,7.37,9.95,0.433031906335941,0.00149113697231834,"*",0.00043164,"TMEM53","GO:0005634//nucleus;GO:0016021//integral component of membrane","NA","NA","K09131//uncharacterized protein;K04460//serine/threonine-protein phosphatase 5 [EC:3.1.3.16]","NP_078863.2//transmembrane protein 53 isoform 1 [Homo sapiens];XP_021573086.1//transmembrane protein 53 isoform X3 [Carlito syrichta];XP_021573085.1//transmembrane protein 53 isoform X2 [Carlito syrichta];XP_008065852.2//transmembrane protein 53 isoform X1 [Carlito syrichta]","1//3;3//A2MP1"]
[92129,1206,0.2,0.27,0.432959407276106,0.811521767461431,"*",0.724446,"RIPPLY1","GO:0005634//nucleus","NA","GO:0045892//negative regulation of transcription, DNA-templated;GO:0032525//somite rostral/caudal axis specification;GO:0060349//bone morphogenesis;GO:0006351//transcription, DNA-templated;GO:0001757//somite specification;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0009880//embryonic pattern specification;GO:0007219//Notch signaling pathway","NA","NP_612391.1//protein ripply1 isoform 1 [Homo sapiens];XP_012666825.1//PREDICTED: protein ripply1 isoform X2 [Otolemur garnettii]","1//3;2//1"]
[8284,5551,0.2,0.27,0.432959407276106,0.542710781315605,"*",0.388398,"KDM5D","GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0046872//metal ion binding;GO:0032453//histone demethylase activity (H3-K4 specific);GO:0003677//DNA binding;GO:0050681//androgen receptor binding;GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;GO:0032452//histone demethylase activity","GO:0002457//T cell antigen processing and presentation;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0034720//histone H3-K4 demethylation;GO:0060765//regulation of androgen receptor signaling pathway","K11446//histone demethylase JARID1 [EC:1.14.11.-]","NP_001140177.1//lysine-specific demethylase 5D isoform 1 [Homo sapiens];NP_001140178.1//lysine-specific demethylase 5D isoform 3 [Homo sapiens];NP_004644.2//lysine-specific demethylase 5D isoform 2 [Homo sapiens]","1//3;4"]
[3310,2370,0.2,0.27,0.432959407276106,0.71835472478429,"*",0.60458,"HSPA6","GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome;GO:0072562//blood microparticle;GO:0005737//cytoplasm;GO:0005814//centriole;GO:0005829//cytosol;GO:0005576//extracellular region;GO:1904813//ficolin-1-rich granule lumen","GO:0005524//ATP binding;GO:0051082//unfolded protein binding;GO:0031072//heat shock protein binding;GO:0019899//enzyme binding;GO:0042623//ATPase activity, coupled","GO:0006986//response to unfolded protein;GO:0043312//neutrophil degranulation;GO:0042026//protein refolding;GO:0034605//cellular response to heat","K03283//heat shock 70kDa protein 1/2/6/8","NP_002146.2//heat shock 70 kDa protein 6 [Homo sapiens]",4]
[126003,714,39.52,53.29,0.431281886175357,{"v":1.59815805432407e-05,"d":"1.60E-05"},"*",{"v":3.20452e-06,"d":"3.20E-06"},"TRAPPC5","NA","NA","NA","K20280//trafficking protein particle complex subunit 5","XP_017735450.1//PREDICTED: trafficking protein particle complex subunit 5 [Rhinopithecus bieti];OWK11881.1//TRAPPC5 [Cervus elaphus hippelaphus];XP_002761715.2//PREDICTED: trafficking protein particle complex subunit 5 isoform X1 [Callithrix jacchus]","1//3;2//1"]
[51282,961,46.73,63.01,0.431231772450063,{"v":1.09792396439791E-6,"d":"1.10E-06"},"*",{"v":1.837892e-07,"d":"1.84E-07"},"SCAND1","GO:0005634//nucleus","GO:0003723//RNA binding;GO:0003677//DNA binding;GO:0042802//identical protein binding;GO:0003700//DNA binding transcription factor activity","GO:0006355//regulation of transcription, DNA-templated;GO:0042127//regulation of cell proliferation;GO:0030851//granulocyte differentiation;GO:0006915//apoptotic process","K09229//KRAB and SCAN domains-containing zinc finger protein;K09230//SCAN domain-containing zinc finger protein","NP_361012.2//SCAN domain-containing protein 1 isoform 2 [Homo sapiens];AAF66832.1//SCAN-related protein RAZ1, partial [Homo sapiens]","3//A2MP1;2//1"]
[91179,3499,0.89,1.2,0.431157164642121,0.253410604242156,"*",0.1436004,"SCARF2","GO:0005925//focal adhesion;GO:0016021//integral component of membrane","NA","GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules","K06776//receptor-type tyrosine-protein phosphatase kappa [EC:3.1.3.48];K02258//cytochrome c oxidase assembly protein subunit 11","XP_007973174.1//PREDICTED: scavenger receptor class F member 2 isoform X1 [Chlorocebus sabaeus];XP_007973175.1//PREDICTED: scavenger receptor class F member 2 isoform X2 [Chlorocebus sabaeus]","6;4"]
[8733,2105,84.41,113.76,0.43050754071919,{"v":1.32486497861163E-25,"d":"1.32E-25"},"*",{"v":4.42064e-27,"d":"4.42E-27"},"GPAA1","GO:0016020//membrane;GO:0042765//GPI-anchor transamidase complex;GO:0005789//endoplasmic reticulum membrane","GO:0015631//tubulin binding;GO:0034235//GPI anchor binding","GO:0016255//attachment of GPI anchor to protein;GO:0006461//protein complex assembly;GO:0006621//protein retention in ER lumen","K05289//glycosylphosphatidylinositol transamidase","NP_003792.1//glycosylphosphatidylinositol anchor attachment 1 protein [Homo sapiens]","3//A2MP1"]
[93185,2269,9.24,12.45,0.430180985539386,0.000665112884825986,"*",0.0001794564,"IGSF8","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","NA","GO:0007399//nervous system development;GO:0006928//movement of cell or subcellular component;GO:0008283//cell proliferation;GO:0007338//single fertilization;GO:0007519//skeletal muscle tissue development","K06730//immunoglobulin superfamily, member 8","XP_012517371.1//PREDICTED: immunoglobulin superfamily member 8 isoform X1 [Propithecus coquereli];NP_443100.1//immunoglobulin superfamily member 8 precursor [Homo sapiens]","1//3;2//1;5"]
[4261,3899,0.72,0.97,0.429987840744815,0.23914880652514,"*",0.1339916,"CIITA","GO:0016605//PML body;GO:0005654//nucleoplasm","GO:0016746//transferase activity, transferring acyl groups;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0044212//transcription regulatory region DNA binding;GO:0008022//protein C-terminus binding;GO:0003713//transcription coactivator activity;GO:0005525//GTP binding;GO:0033613//activating transcription factor binding;GO:0032403//protein complex binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0032966//negative regulation of collagen biosynthetic process;GO:0006351//transcription, DNA-templated;GO:0045345//positive regulation of MHC class I biosynthetic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0046677//response to antibiotic;GO:0034341//response to interferon-gamma;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006955//immune response;GO:0045348//positive regulation of MHC class II biosynthetic process","K08060//class II, major histocompatibility complex, transactivator","XP_011885897.1//PREDICTED: MHC class II transactivator isoform X8 [Cercocebus atys];NP_001273332.1//MHC class II transactivator isoform 3 [Homo sapiens];XP_011885893.1//PREDICTED: MHC class II transactivator isoform X6 [Cercocebus atys]","1//3;3//A2MP1"]
[60598,2550,0.72,0.97,0.429987840744815,0.422196959603659,"*",0.277412,"KCNK15","GO:0005887//integral component of plasma membrane","GO:0022841//potassium ion leak channel activity","GO:0030322//stabilization of membrane potential;GO:0071805//potassium ion transmembrane transport","K04923//potassium channel subfamily K member 15","EAW75900.1//potassium channel, subfamily K, member 15 [Homo sapiens]","3//A2MP1"]
[79033,1365,64.7,87.16,0.429900484236037,{"v":2.39358092488013e-09,"d":"2.39E-09"},"*",{"v":2.81254e-10,"d":"2.81E-10"},"ERI3","NA","GO:0003723//RNA binding;GO:0046872//metal ion binding;GO:0004527//exonuclease activity;GO:0003676//nucleic acid binding","GO:0006259//DNA metabolic process","K18418//ERI1 exoribonuclease 3 [EC:3.1.-.-]","XP_018872689.1//PREDICTED: ERI1 exoribonuclease 3 isoform X4 [Gorilla gorilla gorilla];XP_017396243.1//PREDICTED: ERI1 exoribonuclease 3 isoform X6 [Cebus capucinus imitator];XP_011801358.1//PREDICTED: ERI1 exoribonuclease 3 isoform X5 [Colobus angolensis palliatus];AAC19158.1//unknown, partial [Homo sapiens]","1//3;2//1"]
[11221,2680,1.7,2.29,0.429812851959242,0.161100027527406,"*",0.082799,"DUSP10","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0005737//cytoplasm","GO:0017017//MAP kinase tyrosine/serine/threonine phosphatase activity;GO:0004721//phosphoprotein phosphatase activity;GO:0008432//JUN kinase binding;GO:0004725//protein tyrosine phosphatase activity;GO:0016791//phosphatase activity;GO:0048273//mitogen-activated protein kinase p38 binding;GO:0033549//MAP kinase phosphatase activity","GO:0032496//response to lipopolysaccharide;GO:0010633//negative regulation of epithelial cell migration;GO:0000188//inactivation of MAPK activity;GO:0043508//negative regulation of JUN kinase activity;GO:0035970//peptidyl-threonine dephosphorylation;GO:0046329//negative regulation of JNK cascade;GO:0006470//protein dephosphorylation;GO:0060266//negative regulation of respiratory burst involved in inflammatory response;GO:0016311//dephosphorylation;GO:0045591//positive regulation of regulatory T cell differentiation;GO:1905042//negative regulation of epithelium regeneration;GO:0048709//oligodendrocyte differentiation;GO:0030336//negative regulation of cell migration;GO:0048715//negative regulation of oligodendrocyte differentiation;GO:0002819//regulation of adaptive immune response;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0070303//negative regulation of stress-activated protein kinase signaling cascade;GO:1903753//negative regulation of p38MAPK cascade;GO:0050680//negative regulation of epithelial cell proliferation;GO:1990264//peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity;GO:0044387//negative regulation of protein kinase activity by regulation of protein phosphorylation;GO:0090335//regulation of brown fat cell differentiation","K20216//dual specificity phosphatase 10 [EC:3.1.3.16 3.1.3.48]","NP_009138.1//dual specificity protein phosphatase 10 [Homo sapiens]",5]
[79734,1681,12.68,17.08,0.429753229481083,0.000978166906159015,"*",0.000273414,"KCTD17","GO:0005783//endoplasmic reticulum;GO:0005737//cytoplasm;GO:0031463//Cul3-RING ubiquitin ligase complex","GO:0042802//identical protein binding;GO:0097602//cullin family protein binding;GO:0032403//protein complex binding","GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0032469//endoplasmic reticulum calcium ion homeostasis;GO:0051260//protein homooligomerization;GO:0030030//cell projection organization;GO:0045724//positive regulation of cilium assembly","K21914//BTB/POZ domain-containing protein KCTD2/5/17","NP_078957.2//BTB/POZ domain-containing protein KCTD17 isoform 2 [Homo sapiens];NP_001269613.1//BTB/POZ domain-containing protein KCTD17 isoform 1 [Homo sapiens];XP_007973876.1//PREDICTED: BTB/POZ domain-containing protein KCTD17 isoform X7 [Chlorocebus sabaeus];XP_017364403.1//PREDICTED: BTB/POZ domain-containing protein KCTD17 isoform X1 [Cebus capucinus imitator]","1//3;3//A2MP1"]
[127002,2553,1.99,2.68,0.429464569914124,0.11818969379562,"*",0.0567642,"ATXN7L2","NA","NA","NA","K11318//ataxin-7","NP_001337104.1//ataxin-7-like protein 2 isoform 1 [Homo sapiens];NP_699171.3//ataxin-7-like protein 2 isoform 2 [Homo sapiens];NP_001337103.1//ataxin-7-like protein 2 isoform 3 [Homo sapiens]","1//3;5"]
[60673,1435,40.02,53.89,0.429296419484005,{"v":3.0478719366558e-08,"d":"3.05E-08"},"*",{"v":4.09652e-09,"d":"4.10E-09"},"ATG101","NA","NA","NA","K19730//autophagy-related protein 101","XP_015998147.1//PREDICTED: autophagy-related protein 101 isoform X1 [Rousettus aegyptiacus]","4;1//3"]
[199990,929,57.53,77.46,0.429137031144108,1.0075306173511E-4,"*",{"v":2.3192e-05,"d":"2.32E-05"},"FAAP20","GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0030054//cell junction;GO:0043240//Fanconi anaemia nuclear complex;GO:0005694//chromosome","GO:0070530//K63-linked polyubiquitin modification-dependent protein binding;GO:0043130//ubiquitin binding;GO:0046872//metal ion binding;GO:0031593//polyubiquitin modification-dependent protein binding;GO:0140036//ubiquitin-dependent protein binding","GO:0019985//translesion synthesis;GO:0036297//interstrand cross-link repair;GO:0006974//cellular response to DNA damage stimulus","K12581//CCR4-NOT transcription complex subunit 7/8;K16628//collagen, type VII, alpha;K06236//collagen, type I, alpha;K18952//atypical protein kinase C zeta type [EC:2.7.11.13];K04460//serine/threonine-protein phosphatase 5 [EC:3.1.3.16]","Q6NZ36.2//RecName: Full=Fanconi anemia core complex-associated protein 20; AltName: Full=FANCA-associated protein of 20 kDa; AltName: Full=Fanconi anemia-associated protein of 20 kDa;NP_001269599.1//Fanconi anemia core complex-associated protein 20 isoform 6 [Homo sapiens];AAH66360.1//C1orf86 protein, partial [Homo sapiens];NP_001139782.1//Fanconi anemia core complex-associated protein 20 isoform 1 [Homo sapiens];BAB70965.1//unnamed protein product [Homo sapiens];NP_001243874.1//Fanconi anemia core complex-associated protein 20 isoform 3 [Homo sapiens];NP_001243875.1//Fanconi anemia core complex-associated protein 20 isoform 4 [Homo sapiens];XP_016807965.1//PREDICTED: Fanconi anemia core complex-associated protein 20 isoform X2 [Pan troglodytes]","1//3;2//1"]
[93233,3234,0.26,0.35,0.428843298803874,0.578831958050374,"*",0.421532,"CCDC114","NA","NA","NA","K19720//collagen, type III, alpha","XP_005259470.1//PREDICTED: coiled-coil domain-containing protein 114 isoform X1 [Homo sapiens]","3//A2MP1"]
[10534,803,31.62,42.55,0.428321764214954,0.000220283945116042,"*",{"v":5.40712e-05,"d":"5.41E-05"},"SSSCA1","NA","NA","NA","K11984//U4/U6.U5 tri-snRNP-associated protein 1","XP_013976486.1//Sjoegren syndrome/scleroderma autoantigen 1 isoform X1 [Canis lupus familiaris];XP_009421753.1//PREDICTED: Sjoegren syndrome/scleroderma autoantigen 1 [Pan troglodytes]","1//3;2//1"]
[8357,473,0.55,0.74,0.42809365210429,0.810214969124134,"*",0.724446,"HIST1H3H","NA","NA","NA","K11253//histone H3","XP_021079072.1//LOW QUALITY PROTEIN: uncharacterized protein LOC101825376 [Mesocricetus auratus]","2//1"]
[9001,3876,0.84,1.13,0.427861539636427,0.265186536419214,"*",0.1520664,"HAP1","GO:0005576//extracellular region","NA","NA","K04647//huntingtin-associated protein 1","XP_004282921.1//PREDICTED: LOW QUALITY PROTEIN: huntingtin-associated protein 1 [Orcinus orca];XP_010384888.1//PREDICTED: LOW QUALITY PROTEIN: huntingtin-associated protein 1 [Rhinopithecus roxellana]","1//3;2//1"]
[10882,1517,27.32,36.75,0.427786766320999,{"v":1.54760526718118e-06,"d":"1.55E-06"},"*",{"v":2.63618e-07,"d":"2.64E-07"},"C1QL1","NA","NA","NA","K06237//collagen, type IV, alpha","XP_020369783.1//LOW QUALITY PROTEIN: uncharacterized protein LOC109914588 [Rhincodon typus]",4]
[11316,1062,78.4,105.46,0.427770342377262,{"v":5.04889487701223E-11,"d":"5.05E-11"},"*",{"v":4.90856e-12,"d":"4.91E-12"},"COPE","GO:0005654//nucleoplasm;GO:0030126//COPI vesicle coat;GO:0030137//COPI-coated vesicle;GO:0000139//Golgi membrane;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0030133//transport vesicle;GO:0005789//endoplasmic reticulum membrane","GO:0005198//structural molecule activity","GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0015031//protein transport;GO:0006891//intra-Golgi vesicle-mediated transport","K17268//coatomer subunit epsilon","NP_955474.1//coatomer subunit epsilon isoform b [Homo sapiens];NP_001317398.1//coatomer subunit epsilon isoform d [Homo sapiens];NP_955476.1//coatomer subunit epsilon isoform c [Homo sapiens];NP_009194.2//coatomer subunit epsilon isoform a [Homo sapiens]","1//3;3//A2MP1"]
[25911,864,10.75,14.46,0.427730892474295,0.0237001669900376,"*",0.00908452,"DPCD","GO:0005634//nucleus","NA","GO:0030317//flagellated sperm motility;GO:0007368//determination of left/right symmetry;GO:0021670//lateral ventricle development;GO:0060972//left/right pattern formation;GO:0007283//spermatogenesis;GO:0021678//third ventricle development;GO:0003351//epithelial cilium movement","K20800//protein DPCD","NP_001316673.1//protein DPCD isoform 4 [Homo sapiens];EAW49754.1//deleted in a mouse model of primary ciliary dyskinesia, isoform CRA_a [Homo sapiens];EAW49755.1//deleted in a mouse model of primary ciliary dyskinesia, isoform CRA_b [Homo sapiens]","1//3;2//1"]
[79091,1617,9.54,12.83,0.427459999084171,5.21278689559165E-3,"*",1.687776E-3,"METTL22","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0043234//protein complex","GO:0016279//protein-lysine N-methyltransferase activity;GO:0031072//heat shock protein binding;GO:0008276//protein methyltransferase activity","GO:0006479//protein methylation","K21804//protein N-lysine methyltransferase METTL21A [EC:2.1.1.-];K21806//protein N-lysine methyltransferase METTL21D [EC:2.1.1.-];K17536//connector enhancer of kinase suppressor of Ras 2","NP_077014.3//methyltransferase-like protein 22 [Homo sapiens]","3//A2MP1"]
[100130519,1930,0.87,1.17,0.427421223734676,0.469185673758865,"*",0.31889,"TMEM221","GO:0016021//integral component of membrane","NA","NA","K14000//ribosome-binding protein 1","NP_001177773.1//transmembrane protein 221 [Homo sapiens]","1//3"]
[705,2005,16.94,22.78,0.427333872375913,{"v":1.50084269559748e-05,"d":"1.50E-05"},"*",{"v":2.98778e-06,"d":"2.99E-06"},"BYSL","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0045177//apical part of cell","GO:0003723//RNA binding","GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0007565//female pregnancy;GO:0007155//cell adhesion;GO:0008283//cell proliferation;GO:0001829//trophectodermal cell differentiation;GO:0006364//rRNA processing","K14797//essential nuclear protein 1","NP_004044.3//bystin [Homo sapiens]","3//A2MP1"]
[59271,1878,30.17,40.57,0.42729860605957,{"v":1.74704387878788E-9,"d":"1.75E-09"},"*",{"v":2.02112E-10,"d":"2.02E-10"},"EVA1C","GO:0005576//extracellular region;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0030246//carbohydrate binding;GO:0008201//heparin binding","NA","K00111//glycerol-3-phosphate dehydrogenase [EC:1.1.5.3];K06236//collagen, type I, alpha;K01099//inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]","NP_001273485.1//protein eva-1 homolog C isoform 2 precursor [Homo sapiens];NP_001307673.1//protein eva-1 homolog C isoform 3 [Homo sapiens];NP_478067.2//protein eva-1 homolog C isoform 1 precursor [Homo sapiens]","4;1//3"]
[7041,1790,25.99,34.93,0.426510008922664,{"v":4.24513193296089e-07,"d":"4.25E-07"},"*",{"v":6.65976e-08,"d":"6.66E-08"},"TGFB1I1","GO:0031012//extracellular matrix;GO:0005856//cytoskeleton;GO:0005925//focal adhesion;GO:0005622//intracellular;GO:0016363//nuclear matrix;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0003713//transcription coactivator activity;GO:0050681//androgen receptor binding;GO:0070411//I-SMAD binding;GO:0048495//Roundabout binding","GO:0045165//cell fate commitment;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0045599//negative regulation of fat cell differentiation;GO:0009408//response to heat;GO:0030521//androgen receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0030579//ubiquitin-dependent SMAD protein catabolic process;GO:0007155//cell adhesion;GO:0016331//morphogenesis of embryonic epithelium;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0016055//Wnt signaling pathway;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0030855//epithelial cell differentiation;GO:0008285//negative regulation of cell proliferation","K05760//paxillin","XP_005591807.1//PREDICTED: transforming growth factor beta-1-induced transcript 1 protein isoform X1 [Macaca fascicularis];XP_007988985.1//PREDICTED: LOW QUALITY PROTEIN: transforming growth factor beta-1-induced transcript 1 protein [Chlorocebus sabaeus];BAA24799.1//Hic-5, partial [Homo sapiens]","1//3;4;2//1"]
[10567,821,156.74,210.47,0.425241206763981,{"v":1.15292082844639E-17,"d":"1.15E-17"},"*",{"v":6.59678E-19,"d":"6.60E-19"},"RABAC1","GO:0016020//membrane;GO:0008021//synaptic vesicle;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0005886//plasma membrane","GO:0008022//protein C-terminus binding;GO:0042802//identical protein binding;GO:0070064//proline-rich region binding","NA","K20359//PRA1 family protein 1","NP_006414.2//prenylated Rab acceptor protein 1 [Homo sapiens]","2//1"]
[643911,841,6.92,9.29,0.424906558745928,0.123283662855665,"*",0.0596738,"CRNDE","NA","NA","NA","NA","NP_001295892.1//colorectal neoplasia differentially expressed peptide [Homo sapiens]","1//3"]
[79751,2667,36.75,49.33,0.424721037383403,{"v":5.25020060876758e-14,"d":"5.25E-14"},"*",{"v":3.97364e-15,"d":"3.97E-15"},"SLC25A22","GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane","GO:0005313//L-glutamate transmembrane transporter activity;GO:0005280//hydrogen:amino acid symporter activity;GO:0005314//high-affinity glutamate transmembrane transporter activity","GO:0055085//transmembrane transport;GO:0015813//L-glutamate transport;GO:0006811//ion transport;GO:0006839//mitochondrial transport","K15107//solute carrier family 25 (mitochondrial glutamate transporter), member 18/22","NP_078974.1//mitochondrial glutamate carrier 1 [Homo sapiens]","1//3;5"]
[6521,4953,0.38,0.51,0.42449782852791,0.499160446210821,"*",0.34595,"SLC4A1","GO:0070062//extracellular exosome;GO:0016323//basolateral plasma membrane;GO:0072562//blood microparticle;GO:0030863//cortical cytoskeleton;GO:0005887//integral component of plasma membrane;GO:0030018//Z disc;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0043495//protein membrane anchor;GO:0015108//chloride transmembrane transporter activity;GO:0005452//inorganic anion exchanger activity;GO:0042803//protein homodimerization activity;GO:0015106//bicarbonate transmembrane transporter activity;GO:0015301//anion:anion antiporter activity;GO:0008510//sodium:bicarbonate symporter activity;GO:0030506//ankyrin binding;GO:0008509//anion transmembrane transporter activity","GO:0015701//bicarbonate transport;GO:0006820//anion transport;GO:0006821//chloride transport;GO:0051453//regulation of intracellular pH;GO:0006873//cellular ion homeostasis","K06573//solute carrier family 4 (anion exchanger), member 1","NP_000333.1//band 3 anion transport protein [Homo sapiens]","3//A2MP1"]
[396,1885,633.73,850.46,0.424375070114444,{"v":8.17586905882353e-153,"d":"8.18E-153"},"*",{"v":2.6103e-155,"d":"2.61E-155"},"ARHGDIA","GO:0070062//extracellular exosome;GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0001772//immunological synapse;GO:0005737//cytoplasm","GO:0005094//Rho GDP-dissociation inhibitor activity;GO:0017048//Rho GTPase binding;GO:0051879//Hsp90 protein binding;GO:0005504//fatty acid binding;GO:0019901//protein kinase binding;GO:0005096//GTPase activator activity","GO:0071260//cellular response to mechanical stimulus;GO:0007162//negative regulation of cell adhesion;GO:0071407//cellular response to organic cyclic compound;GO:0043066//negative regulation of apoptotic process;GO:0050772//positive regulation of axonogenesis;GO:0030336//negative regulation of cell migration;GO:0008360//regulation of cell shape;GO:2000249//regulation of actin cytoskeleton reorganization;GO:0006928//movement of cell or subcellular component;GO:0007266//Rho protein signal transduction;GO:0032880//regulation of protein localization;GO:0050771//negative regulation of axonogenesis;GO:0035023//regulation of Rho protein signal transduction;GO:0071526//semaphorin-plexin signaling pathway;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0071461//cellular response to redox state","K12462//Rho GDP-dissociation inhibitor","NP_001288172.1//rho GDP-dissociation inhibitor 1 isoform e [Homo sapiens];NP_001288169.1//rho GDP-dissociation inhibitor 1 isoform c [Homo sapiens];XP_003931694.2//PREDICTED: rho GDP-dissociation inhibitor 1 isoform X1 [Saimiri boliviensis boliviensis];NP_001288171.1//rho GDP-dissociation inhibitor 1 isoform d [Homo sapiens]","1//3;2//1;5"]
[92610,3090,1.96,2.63,0.424209145177094,0.106186646088571,"*",0.0501352,"TIFA","GO:0005622//intracellular","NA","GO:0007249//I-kappaB kinase/NF-kappaB signaling","NA","XP_003899151.2//TRAF-interacting protein with FHA domain-containing protein A isoform X1 [Papio anubis]","2//1"]
[9253,3520,36.44,48.89,0.424016446206087,{"v":6.19574181291759e-18,"d":"6.20E-18"},"*",{"v":3.48302e-19,"d":"3.48E-19"},"NUMBL","GO:0005737//cytoplasm","NA","GO:0007399//nervous system development;GO:0021670//lateral ventricle development;GO:0007409//axonogenesis;GO:0034332//adherens junction organization;GO:0050769//positive regulation of neurogenesis;GO:0019538//protein metabolic process;GO:0021849//neuroblast division in subventricular zone;GO:0019221//cytokine-mediated signaling pathway","K06057//numb","NP_004747.1//numb-like protein isoform a [Homo sapiens];XP_004874284.1//numb-like protein isoform X3 [Heterocephalus glaber]","4;1//3;2//1"]
[23770,1810,102.88,138,0.423705719224946,{"v":8.20863925e-26,"d":"8.21E-26"},"*",{"v":2.71326e-27,"d":"2.71E-27"},"FKBP8","GO:0005740//mitochondrial envelope;GO:0043234//protein complex;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016021//integral component of membrane","GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0042802//identical protein binding;GO:0097718//disordered domain specific binding","GO:0043010//camera-type eye development;GO:0021904//dorsal/ventral neural tube patterning;GO:0030513//positive regulation of BMP signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0035264//multicellular organism growth;GO:0001933//negative regulation of protein phosphorylation;GO:0001708//cell fate specification;GO:0007224//smoothened signaling pathway","K09574//FK506-binding protein 8 [EC:5.2.1.8]","XP_002912777.1//PREDICTED: peptidyl-prolyl cis-trans isomerase FKBP8 isoform X3 [Ailuropoda melanoleuca];XP_006876371.1//PREDICTED: peptidyl-prolyl cis-trans isomerase FKBP8 isoform X2 [Chrysochloris asiatica]","4;1//3"]
[5003,1916,4.75,6.37,0.42336585903799,0.0530765644783118,"*",0.022674,"SLC22A18AS","NA","NA","NA","K08214//MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 18","NP_009036.2//beckwith-Wiedemann syndrome chromosomal region 1 candidate gene B protein isoform a [Homo sapiens];XP_011785497.1//PREDICTED: LOW QUALITY PROTEIN: beckwith-Wiedemann syndrome chromosomal region 1 candidate gene B protein [Colobus angolensis palliatus]","1//3;3//A2MP1"]
[6723,1273,148.83,199.53,0.422940313695785,{"v":7.08526160305344e-26,"d":"7.09E-26"},"*",{"v":2.3242e-27,"d":"2.32E-27"},"SRM","NA","GO:0004766//spermidine synthase activity;GO:0016740//transferase activity;GO:0042803//protein homodimerization activity","GO:1990830//cellular response to leukemia inhibitory factor;GO:0008295//spermidine biosynthetic process;GO:0006596//polyamine biosynthetic process","K00797//spermidine synthase [EC:2.5.1.16]","XP_016809435.1//PREDICTED: spermidine synthase [Pan troglodytes]","2//1"]
[391,1332,71.67,96.06,0.422566454059925,{"v":1.84105606292135e-13,"d":"1.84E-13"},"*",{"v":1.436056e-14,"d":"1.44E-14"},"RHOG","NA","NA","NA","K07863//Ras homolog gene family, member G","XP_011900460.1//PREDICTED: rho-related GTP-binding protein RhoG isoform X1 [Cercocebus atys]","3//A2MP1"]
[6609,2482,6.82,9.14,0.422422426033897,0.00360190241678322,"*",0.001128554,"SMPD1","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005764//lysosome;GO:0005768//endosome;GO:0042599//lamellar body;GO:0043202//lysosomal lumen;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0046872//metal ion binding;GO:0061750//acid sphingomyelin phosphodiesterase activity;GO:0004767//sphingomyelin phosphodiesterase activity;GO:0008270//zinc ion binding;GO:0016798//hydrolase activity, acting on glycosyl bonds","GO:0006685//sphingomyelin catabolic process;GO:0007399//nervous system development;GO:0042493//response to drug;GO:0007165//signal transduction;GO:0043407//negative regulation of MAP kinase activity;GO:0035307//positive regulation of protein dephosphorylation;GO:0006687//glycosphingolipid metabolic process;GO:0023021//termination of signal transduction;GO:0043065//positive regulation of apoptotic process;GO:0042220//response to cocaine;GO:0006684//sphingomyelin metabolic process;GO:0046513//ceramide biosynthetic process","K12350//sphingomyelin phosphodiesterase [EC:3.1.4.12]","BAD93012.1//sphingomyelin phosphodiesterase 1, acid lysosomal isoform 1 precursor variant, partial [Homo sapiens];ADW09002.1//sphingomyelin phosphodiesterase 1 precursor isoform 7 [Homo sapiens]","4;1//3;2//1"]
[1375,2750,9.83,13.17,0.421992023915934,0.000322261448098765,"*",{"v":8.17052e-05,"d":"8.17E-05"},"CPT1B","GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane","GO:0016746//transferase activity, transferring acyl groups;GO:0004095//carnitine O-palmitoyltransferase activity","GO:0015909//long-chain fatty acid transport;GO:0006635//fatty acid beta-oxidation;GO:0006853//carnitine shuttle","K19523//carnitine O-palmitoyltransferase 1, muscle isoform [EC:2.3.1.21]","NP_001138606.1//carnitine O-palmitoyltransferase 1, muscle isoform isoform c [Homo sapiens];NP_004368.1//carnitine O-palmitoyltransferase 1, muscle isoform isoform a [Homo sapiens]","1//3;3//A2MP1;2//1"]
[3106,1624,9.83,13.16,0.420896167394661,0.00517052637415361,"*",1.673122E-3,"HLA-B","NA","NA","NA","K06751//major histocompatibility complex, class I","CEF48040.1//HLA class I antigen [Homo sapiens]",7]
[55507,1038,0.71,0.95,0.420108488826266,0.641531123765432,"*",0.520486,"GPRC5D","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004930//G-protein coupled receptor activity","NA","K04621//G protein-coupled receptor family C group 5 member D","NP_061124.1//G-protein coupled receptor family C group 5 member D [Homo sapiens]","1//3"]
[58485,782,319.09,426.69,0.419224903087494,{"v":6.43703049230769e-32,"d":"6.44E-32"},"*",{"v":1.623966e-33,"d":"1.62E-33"},"TRAPPC1","GO:0005783//endoplasmic reticulum;GO:0005737//cytoplasm;GO:0030008//TRAPP complex;GO:0000139//Golgi membrane;GO:0035578//azurophil granule lumen;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005576//extracellular region","GO:0017112//Rab guanyl-nucleotide exchange factor activity","GO:0006810//transport;GO:0043312//neutrophil degranulation;GO:0048208//COPII vesicle coating;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0061024//membrane organization","K20300//trafficking protein particle complex subunit 1","XP_005067617.2//trafficking protein particle complex subunit 1 [Mesocricetus auratus]","1//3;4"]
[388112,1999,2.32,3.1,0.418143410146666,0.161119652332805,"*",0.082799,"NANOGP8","NA","NA","NA","K10164//homeobox protein Nanog","NP_001342210.1//putative homeobox protein NANOGP8 [Homo sapiens]","1//3"]
[56928,3779,7.29,9.73,0.416520990454175,1.45650478717814E-4,"*",{"v":3.4703e-05,"d":"3.47E-05"},"SPPL2B","GO:0016020//membrane;GO:0005765//lysosomal membrane;GO:0010008//endosome membrane;GO:0005654//nucleoplasm;GO:0005813//centrosome;GO:0030660//Golgi-associated vesicle membrane;GO:0000139//Golgi membrane;GO:0071458//integral component of cytoplasmic side of endoplasmic reticulum membrane;GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0015629//actin cytoskeleton;GO:0005886//plasma membrane","GO:0042803//protein homodimerization activity;GO:0042500//aspartic endopeptidase activity, intramembrane cleaving","GO:0006509//membrane protein ectodomain proteolysis;GO:0033619//membrane protein proteolysis;GO:0031293//membrane protein intracellular domain proteolysis;GO:0010803//regulation of tumor necrosis factor-mediated signaling pathway;GO:0050776//regulation of immune response","K09597//signal peptide peptidase-like 2B [EC:3.4.23.-]","XP_011526440.1//PREDICTED: signal peptide peptidase-like 2B isoform X1 [Homo sapiens]","1//3;2//1"]
[84518,543,26.63,35.51,0.415172931810357,0.0123863015802469,"*",4.39654E-3,"CNFN","NA","NA","NA","NA","EAW57134.1//cornifelin [Homo sapiens]","3//A2MP1"]
[2044,8369,0.06,0.08,0.415037499278844,0.447430099346405,"*",0.299986,"EPHA5","GO:0030425//dendrite;GO:0030424//axon;GO:0009897//external side of plasma membrane;GO:0005791//rough endoplasmic reticulum;GO:0005912//adherens junction;GO:0048471//perinuclear region of cytoplasm;GO:0043025//neuronal cell body;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane","GO:0005004//GPI-linked ephrin receptor activity;GO:0005524//ATP binding;GO:0005003//ephrin receptor activity;GO:0005005//transmembrane-ephrin receptor activity","GO:1904322//cellular response to forskolin;GO:0021766//hippocampus development;GO:0048013//ephrin receptor signaling pathway;GO:0032956//regulation of actin cytoskeleton organization;GO:0048666//neuron development;GO:0019933//cAMP-mediated signaling;GO:0043087//regulation of GTPase activity;GO:0032793//positive regulation of CREB transcription factor activity;GO:0061178//regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0071372//cellular response to follicle-stimulating hormone stimulus;GO:0007411//axon guidance","K05106//Eph receptor A5 [EC:2.7.10.1]","NP_001268695.1//ephrin type-A receptor 5 isoform d [Homo sapiens];NP_004430.4//ephrin type-A receptor 5 isoform a [Homo sapiens];BAD92612.1//ephrin receptor EphA5 isoform a variant, partial [Homo sapiens];NP_001268694.1//ephrin type-A receptor 5 isoform c [Homo sapiens];NP_872272.2//ephrin type-A receptor 5 isoform b [Homo sapiens]","1//3;4;7;2//1"]
[57477,9571,0.06,0.08,0.415037499278844,0.634527201728149,"*",0.4781,"SHROOM4","GO:0016324//apical plasma membrane;GO:0016460//myosin II complex;GO:0005737//cytoplasm;GO:0009925//basal plasma membrane;GO:0030864//cortical actin cytoskeleton;GO:0001725//stress fiber;GO:0009898//cytoplasmic side of plasma membrane;GO:0031941//filamentous actin","GO:0051015//actin filament binding","GO:0050890//cognition;GO:0007015//actin filament organization;GO:0030036//actin cytoskeleton organization;GO:0007420//brain development","K18625//protein Shroom","NP_065768.2//protein Shroom4 [Homo sapiens]","3//A2MP1"]
[8529,2406,0.03,0.04,0.415037499278844,0.646568024008435,"*",0.499032,"CYP4F2","NA","NA","NA","K17729//cytochrome P450 family 4 subfamily F polypeptide 11 [EC:1.14.14.1 1.14.13.194];K17726//leukotriene-B4 20-monooxygenase / phylloquinone omega-hydroxylase [EC:1.14.13.30 1.14.13.194]","XP_004060261.2//PREDICTED: phylloquinone omega-hydroxylase CYP4F2 [Gorilla gorilla gorilla]",4]
[92241,4116,0.03,0.04,0.415037499278844,0.732824878752207,"*",0.623548,"RCSD1","NA","NA","NA","K18615//CapZ-interacting protein","NP_001309852.1//capZ-interacting protein isoform 2 [Homo sapiens];CAB70910.1//hypothetical protein, partial [Homo sapiens]","1//3;3//A2MP1"]
[364,1595,0.39,0.52,0.415037499278844,0.718461606903735,"*",0.60458,"AQP7","GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0015250//water channel activity;GO:0015254//glycerol channel activity;GO:0005215//transporter activity","GO:0006833//water transport;GO:0006091//generation of precursor metabolites and energy;GO:0007588//excretion;GO:0015793//glycerol transport","K08771//aquaporin-7","NP_001305086.1//aquaporin-7 isoform 3 [Homo sapiens];NP_001305087.1//aquaporin-7 isoform 4 [Homo sapiens];XP_021783134.1//aquaporin-7 isoform X2 [Papio anubis];XP_016816209.1//PREDICTED: aquaporin-7 isoform X1 [Pan troglodytes]","1//3;2//1"]
[285367,1233,44.85,59.75,0.41383072794885,{"v":1.01274317996988e-06,"d":"1.01E-06"},"*",{"v":1.68389e-07,"d":"1.68E-07"},"RPUSD3","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0003723//RNA binding;GO:0009982//pseudouridine synthase activity","GO:0006397//mRNA processing;GO:0031119//tRNA pseudouridine synthesis;GO:0001522//pseudouridine synthesis","K01855//tRNA pseudouridine38/39 synthase [EC:5.4.99.45];K05741//diaphanous 2","NP_001136019.1//RNA pseudouridylate synthase domain-containing protein 3 isoform 2 [Homo sapiens];NP_001338665.1//RNA pseudouridylate synthase domain-containing protein 3 isoform 3 [Homo sapiens];NP_775930.2//RNA pseudouridylate synthase domain-containing protein 3 isoform 1 [Homo sapiens];NP_001338667.1//RNA pseudouridylate synthase domain-containing protein 3 isoform 5 [Homo sapiens];NP_001338666.1//RNA pseudouridylate synthase domain-containing protein 3 isoform 4 [Homo sapiens]","4;1//3;2//1"]
[8362,354,1.54,2.05,0.412693558810544,0.718515059891377,"*",0.60458,"HIST1H4K","NA","NA","NA","K11253//histone H3;K11254//histone H4","ELV13502.1//Histone H2B type 1-M [Tupaia chinensis]","2//1"]
[59352,3345,0.76,1.01,0.410283969308209,0.345382536524969,"*",0.209556,"LGR6","GO:0032588//trans-Golgi network membrane;GO:0005887//integral component of plasma membrane;GO:0031982//vesicle;GO:0005886//plasma membrane","GO:0004888//transmembrane signaling receptor activity","GO:0030177//positive regulation of Wnt signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway;GO:0030335//positive regulation of cell migration;GO:0016055//Wnt signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1990523//bone regeneration","K08399//leucine-rich repeat-containing G protein-coupled receptor 6","NP_001017404.1//leucine-rich repeat-containing G-protein coupled receptor 6 isoform 3 [Homo sapiens];NP_001017403.1//leucine-rich repeat-containing G-protein coupled receptor 6 isoform 1 precursor [Homo sapiens];NP_067649.2//leucine-rich repeat-containing G-protein coupled receptor 6 isoform 2 [Homo sapiens]","1//3;2//1"]
[29780,1891,18.79,24.96,0.409652867442193,1.97769697147263E-4,"*",{"v":4.81734e-05,"d":"4.82E-05"},"PARVB","GO:0005856//cytoskeleton;GO:0030018//Z disc;GO:0005925//focal adhesion;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0030027//lamellipodium","GO:0003779//actin binding","GO:0030032//lamellipodium assembly;GO:0071963//establishment or maintenance of cell polarity regulating cell shape;GO:0007155//cell adhesion;GO:0031532//actin cytoskeleton reorganization;GO:0030031//cell projection assembly","K06275//parvin","XP_016884281.1//PREDICTED: beta-parvin isoform X1 [Homo sapiens];AAH46103.2//Parvin, beta [Homo sapiens];NP_001003828.1//beta-parvin isoform a [Homo sapiens];XP_016794838.1//PREDICTED: beta-parvin isoform X2 [Pan troglodytes]","1//3;4;2//1"]
[6626,1646,144.52,191.76,0.408032654216689,{"v":2.97911764361949e-30,"d":"2.98E-30"},"*",{"v":8.03806e-32,"d":"8.04E-32"},"SNRPA","GO:0005685//U1 snRNP;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0019013//viral nucleocapsid","GO:0003723//RNA binding;GO:0030619//U1 snRNA binding;GO:0042802//identical protein binding;GO:1990446//U1 snRNP binding;GO:0035614//snRNA stem-loop binding","GO:0000398//mRNA splicing, via spliceosome;GO:1900363//regulation of mRNA polyadenylation","K11091//U1 small nuclear ribonucleoprotein A","NP_004587.1//U1 small nuclear ribonucleoprotein A [Homo sapiens]",4]
[84628,4806,0.83,1.1,0.406320282177735,0.241967397259664,"*",0.1359798,"NTNG2","NA","NA","NA","K16359//netrin-G2","XP_004375836.1//PREDICTED: netrin-G2 [Trichechus manatus latirostris]","3//A2MP1"]
[6142,671,1057.43,1401.28,0.406183097375507,{"v":1.802314472E-84,"d":"1.80E-84"},"*",{"v":1.353936E-86,"d":"1.35E-86"},"RPL18A","GO:0005840//ribosome;GO:0016020//membrane;GO:0005829//cytosol;GO:0022625//cytosolic large ribosomal subunit","GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome","GO:0006413//translational initiation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0097327//response to antineoplastic agent;GO:0019083//viral transcription;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006412//translation;GO:0006364//rRNA processing","K02882//large subunit ribosomal protein L18Ae","XP_003923253.1//PREDICTED: 60S ribosomal protein L18a [Saimiri boliviensis boliviensis]","3//A2MP1"]
[6916,2385,3.24,4.29,0.404983834614921,0.0709350081759233,"*",0.031502,"TBXAS1","GO:0005623//cell;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0020037//heme binding;GO:0036134//12-hydroxyheptadecatrienoic acid synthase activity;GO:0005506//iron ion binding;GO:0004497//monooxygenase activity;GO:0004796//thromboxane-A synthase activity","GO:0019371//cyclooxygenase pathway;GO:0030644//cellular chloride ion homeostasis;GO:0045907//positive regulation of vasoconstriction;GO:0070542//response to fatty acid;GO:0006690//icosanoid metabolic process;GO:0045471//response to ethanol","K01832//thromboxane-A synthase [EC:5.3.99.5]","NP_001300957.1//thromboxane-A synthase isoform 5 [Homo sapiens];XP_003929807.1//PREDICTED: thromboxane-A synthase [Saimiri boliviensis boliviensis];NP_001124438.1//thromboxane-A synthase isoform 1 [Homo sapiens];NP_001159725.1//thromboxane-A synthase isoform 3 [Homo sapiens]","4;1//3;3//A2MP1;2//1"]
[2867,2069,0.65,0.86,0.403896941673643,0.486458514827995,"*",0.333736,"FFAR2","GO:0042995//cell projection;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0008289//lipid binding;GO:0004930//G-protein coupled receptor activity","GO:0002232//leukocyte chemotaxis involved in inflammatory response;GO:0007186//G-protein coupled receptor signaling pathway;GO:0002720//positive regulation of cytokine production involved in immune response;GO:0042593//glucose homeostasis;GO:0071398//cellular response to fatty acid;GO:0090276//regulation of peptide hormone secretion;GO:0002673//regulation of acute inflammatory response;GO:0002879//positive regulation of acute inflammatory response to non-antigenic stimulus;GO:0019915//lipid storage;GO:2000484//positive regulation of interleukin-8 secretion;GO:0045444//fat cell differentiation;GO:0032722//positive regulation of chemokine production;GO:0002752//cell surface pattern recognition receptor signaling pathway;GO:0002385//mucosal immune response","K04328//free fatty acid receptor 2","NP_005297.1//free fatty acid receptor 2 [Homo sapiens]","2//1"]
[9524,1180,151.51,200.36,0.403181498757468,{"v":4.14286168263473e-22,"d":"4.14E-22"},"*",{"v":1.73246e-23,"d":"1.73E-23"},"TECR","GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005737//cytoplasm","GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors;GO:0017099//very-long-chain-acyl-CoA dehydrogenase activity;GO:0016491//oxidoreductase activity","GO:0030497//fatty acid elongation;GO:0035338//long-chain fatty-acyl-CoA biosynthetic process;GO:0042761//very long-chain fatty acid biosynthetic process;GO:0006629//lipid metabolic process","K10258//very-long-chain enoyl-CoA reductase [EC:1.3.1.93]","NP_001308099.1//very-long-chain enoyl-CoA reductase isoform 2 [Homo sapiens];NP_612510.1//very-long-chain enoyl-CoA reductase isoform 1 [Homo sapiens]","1//3;5"]
[64288,3176,0.56,0.74,0.402098443571346,0.632344384186434,"*",0.475624,"ZSCAN31","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein;K09230//SCAN domain-containing zinc finger protein","XP_020032604.1//zinc finger protein with KRAB and SCAN domains 4 isoform X1 [Castor canadensis];XP_007972111.1//PREDICTED: LOW QUALITY PROTEIN: zinc finger and SCAN domain-containing protein 12 [Chlorocebus sabaeus]","4;1//3;2//1"]
[57018,2946,12.44,16.43,0.401345994819472,{"v":7.94157590538765e-06,"d":"7.94E-06"},"*",{"v":1.513344e-06,"d":"1.51E-06"},"CCNL1","GO:0005634//nucleus;GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0016607//nuclear speck","GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity","GO:0006396//RNA processing;GO:1901409//positive regulation of phosphorylation of RNA polymerase II C-terminal domain;GO:0006355//regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity","K13170//splicing factor, arginine/serine-rich 18;K13165//splicing factor, arginine/serine-rich 12;K02333//DNA polymerase gamma 2","NP_064703.1//cyclin-L1 isoform 1 [Homo sapiens];NP_001295114.1//cyclin-L1 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[35,1964,4.34,5.73,0.400840096312426,0.066416220758483,"*",0.0291626,"ACADS","GO:0005759//mitochondrial matrix;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion","GO:0004085//butyryl-CoA dehydrogenase activity;GO:0050660//flavin adenine dinucleotide binding;GO:0003995//acyl-CoA dehydrogenase activity","GO:0033539//fatty acid beta-oxidation using acyl-CoA dehydrogenase;GO:0006635//fatty acid beta-oxidation","K00248//butyryl-CoA dehydrogenase [EC:1.3.8.1]","NP_001289483.1//short-chain specific acyl-CoA dehydrogenase, mitochondrial isoform 2 precursor [Homo sapiens];NP_000008.1//short-chain specific acyl-CoA dehydrogenase, mitochondrial isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[149473,1381,9.18,12.11,0.399632806280521,0.0685767745986646,"*",0.0302186,"CCDC24","NA","NA","NA","K05038//solute carrier family 6 (neurotransmitter transporter, amino acid) member 5/7/9/14;K02184//formin 2","NP_001336056.1//coiled-coil domain-containing protein 24 isoform 2 [Homo sapiens];NP_689712.1//coiled-coil domain-containing protein 24 isoform 1 [Homo sapiens];NP_001336057.1//coiled-coil domain-containing protein 24 isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[29888,3228,76.58,100.84,0.397028458008379,{"v":4.89381949656751e-30,"d":"4.89E-30"},"*",{"v":1.3388E-31,"d":"1.34E-31"},"STRN4","GO:0016020//membrane;GO:0043234//protein complex;GO:0043197//dendritic spine;GO:0005737//cytoplasm","GO:0070016//armadillo repeat domain binding;GO:0005516//calmodulin binding;GO:0051721//protein phosphatase 2A binding;GO:0032403//protein complex binding","NA","K17608//striatin 1/3/4","NP_001034966.1//striatin-4 isoform 2 [Homo sapiens];NP_037535.2//striatin-4 isoform 1 [Homo sapiens]","1//3;2//1"]
[60370,1422,70.39,92.68,0.396887558168959,{"v":1.92570240175055E-12,"d":"1.93E-12"},"*",{"v":1.652772E-13,"d":"1.65E-13"},"AVPI1","NA","NA","GO:0000187//activation of MAPK activity;GO:0007049//cell cycle","NA","NP_068378.2//arginine vasopressin-induced protein 1 [Homo sapiens]","2//1"]
[11277,1954,10.73,14.11,0.395067911840742,0.00452192079545899,"*",0.001446256,"TREX1","GO:0005635//nuclear envelope;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0032407//MutSalpha complex binding;GO:0042803//protein homodimerization activity;GO:0003676//nucleic acid binding;GO:0032405//MutLalpha complex binding;GO:0008408//3'-5' exonuclease activity;GO:0046872//metal ion binding;GO:0003697//single-stranded DNA binding;GO:0008853//exodeoxyribonuclease III activity;GO:0008296//3'-5'-exodeoxyribonuclease activity","GO:0006281//DNA repair;GO:0032479//regulation of type I interferon production;GO:0006298//mismatch repair;GO:0006260//DNA replication;GO:0006310//DNA recombination;GO:0006259//DNA metabolic process","K10790//three prime repair exonuclease 1 [EC:3.1.11.2]","XP_011836380.1//PREDICTED: three-prime repair exonuclease 1 isoform X2 [Mandrillus leucophaeus];XP_002802855.1//PREDICTED: three-prime repair exonuclease 1 [Macaca mulatta];NP_057465.1//three-prime repair exonuclease 1 isoform a [Homo sapiens]","4;3//A2MP1;5"]
[118472,1128,43.48,57.11,0.393391444229038,{"v":2.04572004181687E-6,"d":"2.05E-06"},"*",{"v":3.55254e-07,"d":"3.55E-07"},"ZNF511","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K01230//mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113];K14802//phospholipid-transporting ATPase [EC:3.6.3.1];K19720//collagen, type III, alpha","AAH15139.1//ZNF511 protein, partial [Homo sapiens]","3//A2MP1"]
[1259,2864,0.16,0.21,0.39231742277876,0.695792519421861,"*",0.578622,"CNGA1","GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0042622//photoreceptor outer segment membrane","GO:0005249//voltage-gated potassium channel activity;GO:0005221//intracellular cyclic nucleotide activated cation channel activity;GO:0030553//cGMP binding","GO:0006810//transport;GO:0016056//rhodopsin mediated signaling pathway;GO:0007601//visual perception;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0042391//regulation of membrane potential","K04948//cyclic nucleotide gated channel alpha 1","NP_001136036.1//cGMP-gated cation channel alpha-1 isoform 1 [Homo sapiens];XP_014993822.1//PREDICTED: cGMP-gated cation channel alpha-1 [Macaca mulatta]","1//3;3//A2MP1"]
[284131,1565,11.39,14.94,0.391412401081125,0.0169790126975477,"*",6.24144E-3,"ENDOV","GO:0005730//nucleolus;GO:0005737//cytoplasm","GO:0000287//magnesium ion binding;GO:0003677//DNA binding;GO:0016891//endoribonuclease activity, producing 5'-phosphomonoesters;GO:0016888//endodeoxyribonuclease activity, producing 5'-phosphomonoesters;GO:0004519//endonuclease activity;GO:0003727//single-stranded RNA binding","GO:0006281//DNA repair","K21813//endonuclease V [EC:3.1.26.-]","NP_001339690.1//endonuclease V isoform 5 [Homo sapiens];NP_775898.2//endonuclease V isoform 1 [Homo sapiens];EAW89609.1//hypothetical protein FLJ35220, isoform CRA_g [Homo sapiens];NP_001339689.1//endonuclease V isoform 4 [Homo sapiens];NP_001158110.1//endonuclease V isoform 3 [Homo sapiens]","4;1//3;2//1"]
[3105,1632,66.56,87.18,0.389341770212905,{"v":5.53218607804132e-13,"d":"5.53E-13"},"*",{"v":4.52646E-14,"d":"4.53E-14"},"HLA-A","NA","NA","NA","K06751//major histocompatibility complex, class I","ALO24308.1//MHC class I antigen [Homo sapiens];P13746.1//RecName: Full=HLA class I histocompatibility antigen, A-11 alpha chain; AltName: Full=MHC class I antigen A*11; Flags: Precursor","1//3;7"]
[6195,3095,8.67,11.34,0.387316741720394,0.000798495999087799,"*",2.19194E-4,"RPS6KA1","NA","NA","NA","K04373//ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]","XP_009941834.1//PREDICTED: ribosomal protein S6 kinase alpha-1 [Opisthocomus hoazin];XP_020014345.1//ribosomal protein S6 kinase alpha-1 isoform X2 [Castor canadensis];XP_009906870.1//PREDICTED: ribosomal protein S6 kinase alpha-1 [Picoides pubescens]","1//3;3//A2MP1"]
[5788,1477,0.88,1.15,0.386058432307078,0.570702319620526,"*",0.414254,"PTPRC","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0030667//secretory granule membrane;GO:0005925//focal adhesion;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0045121//membrane raft;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005001//transmembrane receptor protein tyrosine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0019901//protein kinase binding","GO:2000473//positive regulation of hematopoietic stem cell migration;GO:0002378//immunoglobulin biosynthetic process;GO:0048539//bone marrow development;GO:0002244//hematopoietic progenitor cell differentiation;GO:0042102//positive regulation of T cell proliferation;GO:0007166//cell surface receptor signaling pathway;GO:0010332//response to gamma radiation;GO:0030890//positive regulation of B cell proliferation;GO:2000648//positive regulation of stem cell proliferation;GO:0048864//stem cell development;GO:0001915//negative regulation of T cell mediated cytotoxicity;GO:0006470//protein dephosphorylation;GO:0045860//positive regulation of protein kinase activity;GO:0043312//neutrophil degranulation;GO:0016311//dephosphorylation;GO:0001960//negative regulation of cytokine-mediated signaling pathway;GO:0050853//B cell receptor signaling pathway;GO:0050852//T cell receptor signaling pathway;GO:0051607//defense response to virus;GO:0006933//negative regulation of cell adhesion involved in substrate-bound cell migration;GO:0006469//negative regulation of protein kinase activity;GO:0044770//cell cycle phase transition;GO:0042100//B cell proliferation;GO:0050857//positive regulation of antigen receptor-mediated signaling pathway;GO:0030217//T cell differentiation;GO:0051726//regulation of cell cycle;GO:0051209//release of sequestered calcium ion into cytosol","K06478//receptor-type tyrosine-protein phosphatase C [EC:3.1.3.48]","NP_563578.2//receptor-type tyrosine-protein phosphatase C isoform 2 precursor [Homo sapiens];NP_002829.3//receptor-type tyrosine-protein phosphatase C isoform 1 precursor [Homo sapiens];NP_001254727.1//receptor-type tyrosine-protein phosphatase C isoform 5 precursor [Homo sapiens]","4;1//3;3//A2MP1"]
[131616,997,7.02,9.17,0.385450703290494,0.126962470097787,"*",0.0617724,"TMEM42","GO:0016021//integral component of membrane","NA","NA","K03767//peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8];K10400//kinesin family member 15","NP_653239.1//transmembrane protein 42 [Homo sapiens]","2//1"]
[1603,711,352.44,459.65,0.383158069108334,{"v":7.68599595180723e-27,"d":"7.69E-27"},"*",{"v":2.39616e-28,"d":"2.40E-28"},"DAD1","NA","NA","NA","K12668//oligosaccharyltransferase complex subunit epsilon","XP_006217276.2//PREDICTED: dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 [Vicugna pacos]","3//A2MP1"]
[4151,1078,2.51,3.27,0.381603271547311,0.397323078264239,"*",0.25679,"MB","GO:0070062//extracellular exosome;GO:0005829//cytosol","GO:0046872//metal ion binding;GO:0020037//heme binding;GO:0005344//oxygen carrier activity;GO:0019825//oxygen binding","GO:0015671//oxygen transport;GO:0031444//slow-twitch skeletal muscle fiber contraction;GO:0043353//enucleate erythrocyte differentiation;GO:0007507//heart development;GO:0009725//response to hormone;GO:0050873//brown fat cell differentiation;GO:0042542//response to hydrogen peroxide;GO:0001666//response to hypoxia","K21892//myoglobin","XP_003264736.1//PREDICTED: myoglobin isoform X1 [Nomascus leucogenys];EAW60065.1//myoglobin, isoform CRA_a [Homo sapiens]","1//3;2//1"]
[55630,763,67.56,87.97,0.380842283902436,{"v":8.32749347877204e-06,"d":"8.33E-06"},"*",{"v":1.596268E-6,"d":"1.60E-06"},"SLC39A4","GO:0070062//extracellular exosome;GO:0055038//recycling endosome membrane;GO:0005887//integral component of plasma membrane;GO:0016324//apical plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0005886//plasma membrane","GO:0005385//zinc ion transmembrane transporter activity","GO:0071578//zinc II ion transmembrane import;GO:0034224//cellular response to zinc ion starvation;GO:0007165//signal transduction;GO:0006882//cellular zinc ion homeostasis","K14710//solute carrier family 39 (zinc transporter), member 4","XP_008000121.1//PREDICTED: zinc transporter ZIP4 [Chlorocebus sabaeus];NP_570901.2//zinc transporter ZIP4 isoform 2 precursor [Homo sapiens];NP_060237.2//zinc transporter ZIP4 isoform 1 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[81858,1816,53.54,69.62,0.378884675082905,{"v":3.94519144800523e-11,"d":"3.95E-11"},"*",{"v":3.77626e-12,"d":"3.78E-12"},"SHARPIN","GO:0030425//dendrite;GO:0071797//LUBAC complex;GO:0005829//cytosol;GO:0030054//cell junction;GO:0014069//postsynaptic density","GO:0046872//metal ion binding;GO:0031593//polyubiquitin modification-dependent protein binding;GO:0042802//identical protein binding;GO:0004842//ubiquitin-protein transferase activity;GO:0032403//protein complex binding","GO:0051260//protein homooligomerization;GO:0031424//keratinization;GO:0030262//apoptotic nuclear changes;GO:0010803//regulation of tumor necrosis factor-mediated signaling pathway;GO:0050728//negative regulation of inflammatory response;GO:0007420//brain development;GO:0007005//mitochondrion organization;GO:2000348//regulation of CD40 signaling pathway;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0097039//protein linear polyubiquitination","K20894//shank-associated RH domain-interacting protein","NP_112236.3//sharpin [Homo sapiens]","3//A2MP1"]
[116412,1948,1.9,2.47,0.37851162325373,0.295215336519503,"*",0.1724646,"ZNF837","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_007505752.1//PREDICTED: zinc finger protein 497 [Monodelphis domestica]","1//3"]
[202051,719,1.17,1.52,0.377562793860181,0.658102871755608,"*",0.538092,"SPATA24","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0042803//protein homodimerization activity","GO:0030154//cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0007275//multicellular organism development;GO:0006351//transcription, DNA-templated;GO:0007283//spermatogenesis","K12327//caldesmon;K04559//huntingtin interacting protein 1;K20283//golgin subfamily A member 4;K12478//early endosome antigen 1;K20478//golgin subfamily B member 1","XP_022349019.1//spermatogenesis-associated protein 24 [Enhydra lutris kenyoni]","1//3"]
[116444,3299,0.67,0.87,0.376854305390956,0.467379441903357,"*",0.317282,"GRIN3B","GO:0017146//NMDA selective glutamate receptor complex;GO:0098794//postsynapse;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0005886//plasma membrane;GO:0045211//postsynaptic membrane;GO:0043025//neuronal cell body","GO:0016594//glycine binding;GO:0004970//ionotropic glutamate receptor activity;GO:0005234//extracellularly glutamate-gated ion channel activity;GO:0042165//neurotransmitter binding;GO:0005262//calcium channel activity;GO:0030594//neurotransmitter receptor activity;GO:0005261//cation channel activity","GO:0051924//regulation of calcium ion transport;GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0051205//protein insertion into membrane","K05214//glutamate receptor ionotropic, NMDA 3B","NP_619635.1//glutamate receptor ionotropic, NMDA 3B precursor [Homo sapiens]","2//1"]
[269,1844,0.47,0.61,0.376148485885249,0.672187182191156,"*",0.553858,"AMHR2","GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane","GO:1990272//anti-Mullerian hormone receptor activity;GO:0046872//metal ion binding;GO:0005524//ATP binding;GO:0004872//receptor activity;GO:0004702//signal transducer, downstream of receptor, with serine/threonine kinase activity;GO:0042562//hormone binding;GO:0005026//transforming growth factor beta receptor activity, type II","GO:1902613//negative regulation of anti-Mullerian hormone signaling pathway;GO:0007165//signal transduction;GO:0030509//BMP signaling pathway;GO:0008584//male gonad development;GO:0008585//female gonad development;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007548//sex differentiation;GO:0001880//Mullerian duct regression","K04672//anti-mullerian hormone receptor type-2 [EC:2.7.11.30]","NP_001158162.1//anti-Muellerian hormone type-2 receptor isoform 2 precursor [Homo sapiens];NP_001158163.1//anti-Muellerian hormone type-2 receptor isoform 3 precursor [Homo sapiens];NP_065434.1//anti-Muellerian hormone type-2 receptor isoform 1 precursor [Homo sapiens]","3//A2MP1;2//1"]
[147699,1718,1.92,2.49,0.375039431346925,0.352146928483354,"*",0.214542,"PPM1N","NA","GO:0000287//magnesium ion binding;GO:0004722//protein serine/threonine phosphatase activity;GO:0030145//manganese ion binding","NA","K19790//protein phosphatase 1N [EC:3.1.3.16]","NP_001073870.1//probable protein phosphatase 1N [Homo sapiens]","1//3"]
[199800,2112,7.59,9.83,0.373091530925114,0.0152222239696237,"*",0.00552132,"ADM5","GO:0005576//extracellular region","NA","NA","NA","XP_004061227.1//PREDICTED: putative adrenomedullin-5-like protein [Gorilla gorilla gorilla]","1//3"]
[11140,1693,131.44,170.13,0.372233176735428,{"v":1.68652193300813E-23,"d":"1.69E-23"},"*",{"v":6.49312e-25,"d":"6.49E-25"},"CDC37","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:1990565//HSP90-CDC37 chaperone complex;GO:0005737//cytoplasm","GO:0031072//heat shock protein binding;GO:0051087//chaperone binding;GO:0019901//protein kinase binding;GO:0051879//Hsp90 protein binding;GO:0004713//protein tyrosine kinase activity;GO:0019887//protein kinase regulator activity;GO:0051082//unfolded protein binding;GO:0019900//kinase binding","GO:0006605//protein targeting;GO:0006457//protein folding;GO:0098779//positive regulation of mitophagy in response to mitochondrial depolarization;GO:0038128//ERBB2 signaling pathway;GO:0010608//posttranscriptional regulation of gene expression;GO:0051301//cell division;GO:0060338//regulation of type I interferon-mediated signaling pathway;GO:0060334//regulation of interferon-gamma-mediated signaling pathway;GO:0050821//protein stabilization;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity","K09554//cell division cycle protein 37","NP_008996.1//hsp90 co-chaperone Cdc37 [Homo sapiens]","3//A2MP1"]
[7001,1052,1.09,1.41,0.371367027621867,0.639370064590924,"*",0.48335,"PRDX2","GO:0070062//extracellular exosome;GO:0005623//cell;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0016209//antioxidant activity;GO:0008379//thioredoxin peroxidase activity;GO:0051920//peroxiredoxin activity","GO:0006979//response to oxidative stress;GO:0019430//removal of superoxide radicals;GO:0034599//cellular response to oxidative stress;GO:0043066//negative regulation of apoptotic process;GO:0042744//hydrogen peroxide catabolic process;GO:0042981//regulation of apoptotic process;GO:0045454//cell redox homeostasis","K03386//peroxiredoxin (alkyl hydroperoxide reductase subunit C) [EC:1.11.1.15]","NP_005800.3//peroxiredoxin-2 [Homo sapiens]",5]
[6169,377,623.2,805.31,0.36984901488496,{"v":6.08406779941003e-22,"d":"6.08E-22"},"*",{"v":2.58232E-23,"d":"2.58E-23"},"RPL38","NA","NA","NA","K02923//large subunit ribosomal protein L38e","XP_008010096.1//PREDICTED: 60S ribosomal protein L38 isoform X3 [Chlorocebus sabaeus]","1//3;3//A2MP1"]
[653082,3051,0.24,0.31,0.369233809665719,0.641481626726333,"*",0.520486,"ZDHHC11B","NA","NA","NA","K20027//palmitoyltransferase ZDHHC1/11 [EC:2.3.1.225]","NP_001338232.1//probable palmitoyltransferase ZDHHC11B [Homo sapiens]","1//3"]
[128229,557,6.07,7.83,0.367315791035359,0.816122745179926,"*",0.73402,"TSACC","GO:0005737//cytoplasm","GO:0051087//chaperone binding","NA","K15696//RING finger protein 113B;K06580//ammonium transporter Rh;K01064//wingless-type MMTV integration site family, member 9","NP_001291755.1//TSSK6-activating co-chaperone protein isoform c [Homo sapiens];XP_017365500.1//PREDICTED: TSSK6-activating co-chaperone protein isoform X2 [Cebus capucinus imitator];XP_018880014.1//PREDICTED: TSSK6-activating co-chaperone protein isoform X2 [Gorilla gorilla gorilla];XP_004027019.1//PREDICTED: TSSK6-activating co-chaperone protein isoform X1 [Gorilla gorilla gorilla]","4;1//3"]
[5694,869,173.54,223.74,0.36655496866941,{"v":2.79759449487179e-15,"d":"2.80E-15"},"*",{"v":1.912466E-16,"d":"1.91E-16"},"PSMB6","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000502//proteasome complex;GO:0005829//cytosol;GO:0019774//proteasome core complex, beta-subunit complex;GO:0005839//proteasome core complex","GO:0004175//endopeptidase activity;GO:0004298//threonine-type endopeptidase activity;GO:0045296//cadherin binding","GO:0043687//post-translational protein modification;GO:0038061//NIK/NF-kappaB signaling;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0006521//regulation of cellular amino acid metabolic process;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0016579//protein deubiquitination;GO:0043488//regulation of mRNA stability;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0000209//protein polyubiquitination;GO:0055085//transmembrane transport;GO:0000165//MAPK cascade;GO:0050852//T cell receptor signaling pathway;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0016032//viral process;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:1902036//regulation of hematopoietic stem cell differentiation","K02738//20S proteasome subunit beta 1 [EC:3.4.25.1]","XP_008008144.1//PREDICTED: proteasome subunit beta type-6 isoform X1 [Chlorocebus sabaeus];XP_008008145.1//PREDICTED: proteasome subunit beta type-6 isoform X2 [Chlorocebus sabaeus]","1//3;2//1"]
[51181,854,56.04,72.18,0.365142187466415,{"v":2.23112103249317E-5,"d":"2.23E-05"},"*",{"v":4.5994e-06,"d":"4.60E-06"},"DCXR","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005903//brush border;GO:0005881//cytoplasmic microtubule;GO:0005886//plasma membrane;GO:0005902//microvillus","GO:0042802//identical protein binding;GO:0050038//L-xylulose reductase (NADP+) activity;GO:0016655//oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor","GO:0019640//glucuronate catabolic process to xylulose 5-phosphate;GO:0006006//glucose metabolic process;GO:0005997//xylulose metabolic process;GO:0006739//NADP metabolic process;GO:0051289//protein homotetramerization;GO:0042732//D-xylose metabolic process;GO:0055114//oxidation-reduction process","K03331//L-xylulose reductase [EC:1.1.1.10]","NP_057370.1//L-xylulose reductase isoform 1 [Homo sapiens];NP_001182147.1//L-xylulose reductase isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[133,1606,27.01,34.75,0.363519337989265,{"v":4.28973421940685e-05,"d":"4.29E-05"},"*",{"v":9.32656e-06,"d":"9.33E-06"},"ADM","GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0005102//receptor binding;GO:0031700//adrenomedullin receptor binding;GO:0005179//hormone activity","GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0031100//animal organ regeneration;GO:0031623//receptor internalization;GO:0045906//negative regulation of vasoconstriction;GO:0043065//positive regulation of apoptotic process;GO:0043116//negative regulation of vascular permeability;GO:0060712//spongiotrophoblast layer development;GO:0045766//positive regulation of angiogenesis;GO:0001570//vasculogenesis;GO:0030819//positive regulation of cAMP biosynthetic process;GO:0008285//negative regulation of cell proliferation;GO:0009611//response to wounding;GO:0046879//hormone secretion;GO:0007565//female pregnancy;GO:0007165//signal transduction;GO:0008209//androgen metabolic process;GO:0007507//heart development;GO:0001666//response to hypoxia;GO:0042475//odontogenesis of dentin-containing tooth;GO:0019933//cAMP-mediated signaling;GO:0003073//regulation of systemic arterial blood pressure;GO:0008015//blood circulation;GO:0001843//neural tube closure;GO:0019731//antibacterial humoral response;GO:0097084//vascular smooth muscle cell development;GO:0050829//defense response to Gram-negative bacterium;GO:0032496//response to lipopolysaccharide;GO:0097647//amylin receptor signaling pathway;GO:0030816//positive regulation of cAMP metabolic process;GO:0031102//neuron projection regeneration;GO:0050830//defense response to Gram-positive bacterium;GO:0051384//response to glucocorticoid;GO:0010460//positive regulation of heart rate;GO:0032868//response to insulin;GO:0009409//response to cold;GO:0035809//regulation of urine volume;GO:2001214//positive regulation of vasculogenesis;GO:0007267//cell-cell signaling;GO:0006701//progesterone biosynthetic process;GO:0006171//cAMP biosynthetic process;GO:0007568//aging;GO:0002026//regulation of the force of heart contraction;GO:0060670//branching involved in labyrinthine layer morphogenesis;GO:0042594//response to starvation;GO:0048589//developmental growth;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0002031//G-protein coupled receptor internalization;GO:0008284//positive regulation of cell proliferation","K12333//adrenomedullin","NP_001115.1//ADM precursor [Homo sapiens]","2//1"]
[100526693,3987,2.97,3.82,0.363109707234983,0.0511483059758611,"*",0.0217542,"ARPC4-TTLL3","GO:0005885//Arp2/3 protein complex","GO:0005524//ATP binding;GO:0070735//protein-glycine ligase activity","GO:0034314//Arp2/3 complex-mediated actin nucleation;GO:0018094//protein polyglycylation;GO:0030041//actin filament polymerization","K16608//tubulin monoglycylase TTLL3/8 [EC:6.3.2.-]","NP_001185722.1//ARPC4-TTLL3 fusion protein [Homo sapiens]","1//3"]
[29944,3647,0.07,0.09,0.362570079384708,0.811237322397476,"*",0.724446,"PNMA3","GO:0005730//nucleolus","GO:0008270//zinc ion binding;GO:0003676//nucleic acid binding","GO:0043065//positive regulation of apoptotic process","K17561//coiled-coil domain-containing protein 8;K02183//calmodulin;K12015//tripartite motif-containing protein 39 [EC:2.3.2.27]","NP_001269464.1//paraneoplastic antigen Ma3 isoform 2 [Homo sapiens];NP_037496.4//paraneoplastic antigen Ma3 isoform 1 [Homo sapiens]","1//3;5"]
[2987,963,51.79,66.58,0.362415312009415,{"v":9.64705095875899e-07,"d":"9.65E-07"},"*",{"v":1.596166E-7,"d":"1.60E-07"},"GUK1","GO:0005829//cytosol","GO:0005524//ATP binding;GO:0004385//guanylate kinase activity","GO:0034436//glycoprotein transport;GO:0046034//ATP metabolic process;GO:0046711//GDP biosynthetic process;GO:0046054//dGMP metabolic process;GO:0019673//GDP-mannose metabolic process;GO:0015949//nucleobase-containing small molecule interconversion;GO:0046060//dATP metabolic process;GO:0006185//dGDP biosynthetic process;GO:0006163//purine nucleotide metabolic process","K00942//guanylate kinase [EC:2.7.4.8]","NP_001229769.1//guanylate kinase isoform c [Homo sapiens];NP_001152862.1//guanylate kinase isoform a [Homo sapiens];XP_018887051.1//PREDICTED: guanylate kinase isoform X2 [Gorilla gorilla gorilla]","1//3;5"]
[205251,2054,15.43,19.82,0.361218900615753,0.000631024384895105,"*",0.0001694688,"SMIM37","NA","NA","NA","K13024//inositol-hexakisphosphate/diphosphoinositol-pentakisphosphate 1-kinase [EC:2.7.4.24];K12606//CCR4-NOT transcription complex subunit 9;K17985//activating molecule in BECN1-regulated autophagy protein 1","NP_001342180.1//uncharacterized protein encoded by LINC00116 [Homo sapiens]","1//3"]
[7057,7253,4.59,5.89,0.359773480416653,0.000377957681461632,"*",{"v":9.71276e-05,"d":"9.71E-05"},"THBS1","GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0005577//fibrinogen complex;GO:0031091//platelet alpha granule;GO:0009897//external side of plasma membrane","GO:0070052//collagen V binding;GO:0030169//low-density lipoprotein particle binding;GO:0001968//fibronectin binding;GO:0043236//laminin binding;GO:0005178//integrin binding;GO:0005509//calcium ion binding;GO:0017134//fibroblast growth factor binding;GO:0008201//heparin binding;GO:0001786//phosphatidylserine binding;GO:0070051//fibrinogen binding","GO:0010763//positive regulation of fibroblast migration;GO:0010751//negative regulation of nitric oxide mediated signal transduction;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0016477//cell migration;GO:0032026//response to magnesium ion;GO:0030823//regulation of cGMP metabolic process;GO:0051918//negative regulation of fibrinolysis;GO:0002581//negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;GO:0018149//peptide cross-linking;GO:0010748//negative regulation of plasma membrane long-chain fatty acid transport;GO:0009749//response to glucose;GO:0045766//positive regulation of angiogenesis;GO:0001937//negative regulation of endothelial cell proliferation;GO:0042493//response to drug;GO:0043032//positive regulation of macrophage activation;GO:0040037//negative regulation of fibroblast growth factor receptor signaling pathway;GO:2001027//negative regulation of endothelial cell chemotaxis;GO:0043652//engulfment of apoptotic cell;GO:0002605//negative regulation of dendritic cell antigen processing and presentation;GO:0051592//response to calcium ion;GO:1902043//positive regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0007155//cell adhesion;GO:0050921//positive regulation of chemotaxis;GO:0002544//chronic inflammatory response;GO:0001953//negative regulation of cell-matrix adhesion;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0002040//sprouting angiogenesis;GO:0051897//positive regulation of protein kinase B signaling;GO:0032695//negative regulation of interleukin-12 production;GO:0045727//positive regulation of translation;GO:0007050//cell cycle arrest;GO:2000353//positive regulation of endothelial cell apoptotic process;GO:0010754//negative regulation of cGMP-mediated signaling;GO:0000187//activation of MAPK activity;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0016525//negative regulation of angiogenesis;GO:0010757//negative regulation of plasminogen activation;GO:0042535//positive regulation of tumor necrosis factor biosynthetic process;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0006955//immune response;GO:0043537//negative regulation of blood vessel endothelial cell migration;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway","K16857//thrombospondin 1","BAD93149.1//thrombospondin 1 precursor variant, partial [Homo sapiens]","3//A2MP1"]
[2787,823,126.38,162.17,0.359738787633154,{"v":2.18763785395293E-10,"d":"2.19E-10"},"*",{"v":2.26926E-11,"d":"2.27E-11"},"GNG5","NA","NA","NA","K04542//guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5","XP_018878468.1//PREDICTED: guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 isoform X1 [Gorilla gorilla gorilla]","2//1"]
[9260,1594,56.91,72.92,0.357632381906502,{"v":1.33314411722429e-10,"d":"1.33E-10"},"*",{"v":1.346998E-11,"d":"1.35E-11"},"PDLIM7","GO:0001726//ruffle;GO:0001725//stress fiber;GO:0005634//nucleus;GO:0005925//focal adhesion;GO:0005913//cell-cell adherens junction;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0005737//cytoplasm","GO:0046872//metal ion binding","GO:0030036//actin cytoskeleton organization;GO:0006898//receptor-mediated endocytosis;GO:0045669//positive regulation of osteoblast differentiation;GO:0001503//ossification;GO:0007411//axon guidance","K19867//LIM domain-binding protein 3","XP_008013637.1//PREDICTED: PDZ and LIM domain protein 7 isoform X3 [Chlorocebus sabaeus];XP_008013635.1//PREDICTED: PDZ and LIM domain protein 7 isoform X1 [Chlorocebus sabaeus];XP_008013640.1//PREDICTED: PDZ and LIM domain protein 7 isoform X5 [Chlorocebus sabaeus]","4;2//1"]
[10046,4532,2.04,2.61,0.355480654598389,0.0794673239311494,"*",0.0358384,"MAMLD1","GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0005794//Golgi apparatus;GO:0005813//centrosome","NA","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0008584//male gonad development","K19512//mastermind-like domain-containing protein 1","NP_001170936.1//mastermind-like domain-containing protein 1 isoform 1 [Homo sapiens];NP_001170937.1//mastermind-like domain-containing protein 1 isoform 3 [Homo sapiens];NP_005482.2//mastermind-like domain-containing protein 1 isoform 2 [Homo sapiens]","4;2//1"]
[6781,3897,4.01,5.13,0.355356589152134,0.0232622649729907,"*",0.00889628,"STC1","GO:0005634//nucleus;GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0005179//hormone activity","GO:0001886//endothelial cell morphogenesis;GO:0010596//negative regulation of endothelial cell migration;GO:0003421//growth plate cartilage axis specification;GO:0051926//negative regulation of calcium ion transport;GO:0044070//regulation of anion transport;GO:0035988//chondrocyte proliferation;GO:0090280//positive regulation of calcium ion import;GO:1903403//negative regulation of renal phosphate excretion;GO:0086004//regulation of cardiac muscle cell contraction;GO:0006874//cellular calcium ion homeostasis","K04650//nuclear receptor co-repressor 1","XP_006028766.1//PREDICTED: stanniocalcin-1 [Alligator sinensis]","2//1"]
[79897,561,72.46,92.55,0.353048184304649,0.000272696653323301,"*",{"v":6.80632e-05,"d":"6.81E-05"},"RPP21","GO:0005654//nucleoplasm;GO:0030681//multimeric ribonuclease P complex;GO:0005655//nucleolar ribonuclease P complex","GO:0046872//metal ion binding;GO:0004526//ribonuclease P activity","GO:0042493//response to drug;GO:0001682//tRNA 5'-leader removal;GO:0006364//rRNA processing;GO:0008033//tRNA processing","K03540//ribonuclease P protein subunit RPR2 [EC:3.1.26.5]","XP_007971483.1//PREDICTED: ribonuclease P protein subunit p21 isoform X1 [Chlorocebus sabaeus];XP_007971484.1//PREDICTED: ribonuclease P protein subunit p21 isoform X2 [Chlorocebus sabaeus];NP_001186049.1//ribonuclease P protein subunit p21 isoform 1 [Homo sapiens]","1//3;2//1"]
[9124,1598,93.18,118.79,0.35032115649181,{"v":3.71869350588235e-14,"d":"3.72E-14"},"*",{"v":2.77028e-15,"d":"2.77E-15"},"PDLIM1","GO:0005856//cytoskeleton;GO:0005925//focal adhesion;GO:0005913//cell-cell adherens junction;GO:0005667//transcription factor complex;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0098641//cadherin binding involved in cell-cell adhesion;GO:0003713//transcription coactivator activity","GO:0006979//response to oxidative stress;GO:0006355//regulation of transcription, DNA-templated;GO:0001666//response to hypoxia","K19867//LIM domain-binding protein 3","NP_066272.1//PDZ and LIM domain protein 1 [Homo sapiens]","3//A2MP1"]
[83719,977,9.25,11.79,0.350038447576088,0.345813376237624,"*",0.209904,"YPEL3","GO:0005730//nucleolus","GO:0046872//metal ion binding","GO:2000774//positive regulation of cellular senescence","K14697//solute carrier family 30 (zinc transporter), member 10;K18080//tensin;K12567//titin [EC:2.7.11.1]","XP_011980257.1//PREDICTED: protein yippee-like 3 isoform X2, partial [Ovis aries musimon];XP_012319981.1//protein yippee-like 3 isoform X2 [Aotus nancymaae]","1//3;4"]
[9507,4346,1.32,1.68,0.347923303420307,0.179830332839034,"*",0.0941368,"ADAMTS4","GO:0031012//extracellular matrix;GO:0005615//extracellular space;GO:0016607//nuclear speck;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix","GO:0002020//protease binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding","GO:0022617//extracellular matrix disassembly;GO:0006508//proteolysis;GO:0001501//skeletal system development","K07764//a disintegrin and metalloproteinase with thrombospondin motifs 4 [EC:3.4.24.82]","XP_017370582.1//PREDICTED: A disintegrin and metalloproteinase with thrombospondin motifs 4 isoform X1 [Cebus capucinus imitator];NP_001307265.1//A disintegrin and metalloproteinase with thrombospondin motifs 4 isoform 2 precursor [Homo sapiens]","1//3;5"]
[124641,1076,89.14,113.4,0.347275774216937,{"v":3.49710293723849e-09,"d":"3.50E-09"},"*",{"v":4.18584E-10,"d":"4.19E-10"},"OVCA2","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0016787//hydrolase activity","GO:0032526//response to retinoic acid","K07561//2-(3-amino-3-carboxypropyl)histidine synthase [EC:2.5.1.108]","NP_543012.1//esterase OVCA2 [Homo sapiens]","2//1"]
[9311,2291,10.4,13.23,0.347229533250222,0.0040923767586343,"*",1.298114E-3,"ASIC3","NA","NA","NA","K04830//acid-sensing ion channel 3","XP_003815113.1//PREDICTED: acid-sensing ion channel 3 isoform X3 [Pan paniscus];XP_003815115.1//PREDICTED: acid-sensing ion channel 3 isoform X1 [Pan paniscus];XP_003815114.1//PREDICTED: acid-sensing ion channel 3 isoform X2 [Pan paniscus]","3//A2MP1"]
[169841,2602,0.37,0.47,0.345135486048687,0.595939190755374,"*",0.439064,"ZNF169","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","XP_003912049.3//zinc finger protein 169 isoform X2 [Papio anubis];XP_009187478.2//zinc finger protein 169 isoform X1 [Papio anubis];XP_011769568.1//PREDICTED: zinc finger protein 169 isoform X1 [Macaca nemestrina]","1//3;3//A2MP1;2//1"]
[150372,5570,0.26,0.33,0.343954401217361,0.498926269967474,"*",0.345694,"NFAM1","GO:0009986//cell surface;GO:0045121//membrane raft;GO:0005622//intracellular;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0035577//azurophil granule membrane","GO:0004888//transmembrane signaling receptor activity","GO:0050853//B cell receptor signaling pathway;GO:0007165//signal transduction;GO:0045577//regulation of B cell differentiation;GO:0050861//positive regulation of B cell receptor signaling pathway;GO:0035556//intracellular signal transduction;GO:0001819//positive regulation of cytokine production;GO:0006954//inflammatory response;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0043312//neutrophil degranulation;GO:0030183//B cell differentiation","K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K02927//large subunit ribosomal protein L40e;K15696//RING finger protein 113B;K17985//activating molecule in BECN1-regulated autophagy protein 1","NP_666017.1//NFAT activation molecule 1 isoform 1 precursor [Homo sapiens];NP_001305252.1//NFAT activation molecule 1 isoform 2 precursor [Homo sapiens]","6;1//3"]
[1582,3950,0.78,0.99,0.343954401217361,0.379909520256719,"*",0.237164,"CYP8B1","GO:0031090//organelle membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0020037//heme binding;GO:0033778//7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity;GO:0005506//iron ion binding;GO:0008397//sterol 12-alpha-hydroxylase activity;GO:0019825//oxygen binding","GO:0016125//sterol metabolic process;GO:0006699//bile acid biosynthetic process","K07431//sterol 12-alpha-hydroxylase [EC:1.14.18.8 1.14.13.96]","NP_004382.2//7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase [Homo sapiens]","2//1"]
[6232,375,1425.41,1806.29,0.341652585436781,{"v":3.51101887197232e-41,"d":"3.51E-41"},"*",{"v":6.3521E-43,"d":"6.35E-43"},"RPS27","GO:0005840//ribosome","GO:0003735//structural constituent of ribosome","GO:0006412//translation","K02978//small subunit ribosomal protein S27e","XP_004619237.1//PREDICTED: 40S ribosomal protein S27 [Sorex araneus];XP_017707282.1//PREDICTED: 40S ribosomal protein S27-like [Rhinopithecus bieti]","1//3;5"]
[100507507,1741,4.17,5.28,0.34049054591379,0.174426549019608,"*",0.090773,"LOC100507507","NA","NA","NA","NA","XP_008972238.1//PREDICTED: uncharacterized protein LOC100976922 [Pan paniscus]","2//1"]
[8178,4077,2.9,3.67,0.339727162828278,0.0647648175007149,"*",0.0283564,"ELL","GO:0005654//nucleoplasm;GO:0008023//transcription elongation factor complex;GO:0035327//transcriptionally active chromatin;GO:0016607//nuclear speck;GO:0035363//histone locus body;GO:0015030//Cajal body","GO:0019902//phosphatase binding;GO:0003746//translation elongation factor activity","GO:0045945//positive regulation of transcription from RNA polymerase III promoter;GO:0042795//snRNA transcription from RNA polymerase II promoter;GO:0001701//in utero embryonic development;GO:0006366//transcription from RNA polymerase II promoter;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0032786//positive regulation of DNA-templated transcription, elongation;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0010923//negative regulation of phosphatase activity;GO:0042796//snRNA transcription from RNA polymerase III promoter","K15183//RNA polymerase II elongation factor ELL","NP_006523.1//RNA polymerase II elongation factor ELL [Homo sapiens]","3//A2MP1"]
[8892,1557,41.96,53.02,0.337521992289991,{"v":2.81578565517241e-06,"d":"2.82E-06"},"*",{"v":5.00968e-07,"d":"5.01E-07"},"EIF2B2","GO:0005851//eukaryotic translation initiation factor 2B complex;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0003743//translation initiation factor activity;GO:0005524//ATP binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005525//GTP binding","GO:0042552//myelination;GO:0051716//cellular response to stimulus;GO:0043434//response to peptide hormone;GO:0009408//response to heat;GO:0001541//ovarian follicle development;GO:0007417//central nervous system development;GO:0006413//translational initiation;GO:0065009//regulation of molecular function;GO:0006446//regulation of translational initiation;GO:0014003//oligodendrocyte development;GO:0009749//response to glucose","K03754//translation initiation factor eIF-2B subunit beta","NP_055054.1//translation initiation factor eIF-2B subunit beta [Homo sapiens]","3//A2MP1"]
[51458,1952,3.5,4.42,0.336691447559103,0.142817238798155,"*",0.0717126,"RHCG","GO:0070062//extracellular exosome;GO:0016323//basolateral plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016324//apical plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0005886//plasma membrane","GO:0008519//ammonium transmembrane transporter activity;GO:0042802//identical protein binding;GO:0030506//ankyrin binding","GO:0015695//organic cation transport;GO:0042592//homeostatic process;GO:0006885//regulation of pH;GO:0006873//cellular ion homeostasis;GO:0015696//ammonium transport;GO:0015837//amine transport;GO:0070634//transepithelial ammonium transport;GO:0072488//ammonium transmembrane transport;GO:0030855//epithelial cell differentiation","K06580//ammonium transporter Rh","NP_057405.1//ammonium transporter Rh type C [Homo sapiens]","1//3;2//1"]
[122704,1142,33.89,42.78,0.33607684568105,0.000428761858188825,"*",1.114448E-4,"MRPL52","GO:0005762//mitochondrial large ribosomal subunit;GO:0005743//mitochondrial inner membrane","GO:0003735//structural constituent of ribosome","GO:0032543//mitochondrial translation;GO:0006412//translation;GO:0070126//mitochondrial translational termination;GO:0070125//mitochondrial translational elongation","K17433//large subunit ribosomal protein L52","XP_009209406.2//39S ribosomal protein L52, mitochondrial isoform X1 [Papio anubis];CAD66556.1//unnamed protein product, partial [Homo sapiens];NP_851824.1//39S ribosomal protein L52, mitochondrial isoform e [Homo sapiens];NP_001305799.1//39S ribosomal protein L52, mitochondrial isoform f [Homo sapiens]","1//3;2//1"]
[3704,1182,45.59,57.49,0.334593621548739,{"v":1.04122511361442E-5,"d":"1.04E-05"},"*",{"v":2.02522e-06,"d":"2.03E-06"},"ITPA","GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0035870//dITP diphosphatase activity;GO:0042802//identical protein binding;GO:0035529//NADH pyrophosphatase activity;GO:0036220//ITP diphosphatase activity;GO:0047429//nucleoside-triphosphate diphosphatase activity;GO:0036222//XTP diphosphatase activity;GO:0046872//metal ion binding;GO:0000166//nucleotide binding","GO:0009143//nucleoside triphosphate catabolic process;GO:0051276//chromosome organization;GO:0009204//deoxyribonucleoside triphosphate catabolic process;GO:0006195//purine nucleotide catabolic process;GO:0006193//ITP catabolic process;GO:0009117//nucleotide metabolic process","K01519//inosine triphosphate pyrophosphatase [EC:3.6.1.-]","NP_001254552.1//inosine triphosphate pyrophosphatase isoform c [Homo sapiens];NP_852470.1//inosine triphosphate pyrophosphatase isoform b [Homo sapiens];NP_258412.1//inosine triphosphate pyrophosphatase isoform a [Homo sapiens];AAG43165.1//brain my049 protein [Homo sapiens];NP_001311169.1//inosine triphosphate pyrophosphatase isoform e [Homo sapiens]","1//3;3//A2MP1"]
[100463482,1395,837.19,1054.54,0.33298683514678,{"v":4.28776954851485e-95,"d":"4.29E-95"},"*",{"v":2.71106e-97,"d":"2.71E-97"},"MTRNR2L6","NA","NA","NA","NA","NA","2//1"]
[23732,8217,0.54,0.68,0.332575339086871,0.345844182718086,"*",0.209966,"FRRS1L","GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0045202//synapse;GO:0005886//plasma membrane","NA","GO:1900449//regulation of glutamate receptor signaling pathway","K17985//activating molecule in BECN1-regulated autophagy protein 1;K21111//band 4.1-like protein 4B;K03843//alpha-1,3/alpha-1,6-mannosyltransferase [EC:2.4.1.132 2.4.1.257]","NP_055149.2//DOMON domain-containing protein FRRS1L [Homo sapiens]","3//A2MP1"]
[53407,2153,8.23,10.36,0.332059667264928,0.0502851602660754,"*",0.0212958,"STX18","GO:0005783//endoplasmic reticulum;GO:0005622//intracellular;GO:0031201//SNARE complex;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0000139//Golgi membrane","GO:0005484//SNAP receptor activity;GO:0019904//protein domain specific binding","GO:1903358//regulation of Golgi organization;GO:0090158//endoplasmic reticulum membrane organization;GO:1902953//positive regulation of ER to Golgi vesicle-mediated transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:1902117//positive regulation of organelle assembly;GO:0016192//vesicle-mediated transport;GO:0006886//intracellular protein transport;GO:0006888//ER to Golgi vesicle-mediated transport","K08492//syntaxin 18","AAV38937.1//syntaxin 18 [Homo sapiens];NP_001333210.1//syntaxin-18 isoform 2 [Homo sapiens];NP_058626.1//syntaxin-18 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[92691,3477,0.7,0.88,0.330148601692331,0.475751343245228,"*",0.324514,"TMEM169","GO:0016021//integral component of membrane","NA","NA","K22069//LYR motif-containing protein 4;K12581//CCR4-NOT transcription complex subunit 7/8","NP_612399.1//transmembrane protein 169 [Homo sapiens]","1//3;3//A2MP1"]
[1186,4236,29.57,37.16,0.329616258262328,{"v":6.94473965924984e-11,"d":"6.94E-11"},"*",{"v":6.83866e-12,"d":"6.84E-12"},"CLCN7","GO:0016020//membrane;GO:0005765//lysosomal membrane;GO:0031410//cytoplasmic vesicle;GO:0016021//integral component of membrane","GO:0005524//ATP binding;GO:0005247//voltage-gated chloride channel activity;GO:0005254//chloride channel activity;GO:0015297//antiporter activity","GO:0006810//transport;GO:0009268//response to pH;GO:0034220//ion transmembrane transport;GO:1902476//chloride transmembrane transport","K05016//chloride channel 7","NP_001278.1//H(+)/Cl(-) exchange transporter 7 isoform a [Homo sapiens];NP_001107803.1//H(+)/Cl(-) exchange transporter 7 isoform b [Homo sapiens]","2//1;5"]
[126070,4181,0.39,0.49,0.32930762525296,0.612688965366876,"*",0.457388,"ZNF440","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_018872019.1//PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 69-like [Gorilla gorilla gorilla]","2//1"]
[64978,1614,74.82,93.96,0.328622747461371,{"v":2.66417380214541e-10,"d":"2.66E-10"},"*",{"v":2.7986E-11,"d":"2.80E-11"},"MRPL38","GO:0005762//mitochondrial large ribosomal subunit;GO:0005743//mitochondrial inner membrane","NA","GO:0070126//mitochondrial translational termination;GO:0070125//mitochondrial translational elongation","K17419//large subunit ribosomal protein L38","NP_115867.2//39S ribosomal protein L38, mitochondrial [Homo sapiens]","3//A2MP1"]
[391322,943,2.08,2.61,0.327466278428792,0.83223325666897,"*",0.753876,"LOC391322","NA","NA","NA","K10028//D-dopachrome decarboxylase [EC:4.1.1.84]","XP_001170336.2//PREDICTED: D-dopachrome decarboxylase [Pan troglodytes]","1//3;2//1"]
[516,594,356.9,447.51,0.326400019625079,{"v":2.25010905e-16,"d":"2.25E-16"},"*",{"v":1.419876E-17,"d":"1.42E-17"},"ATP5MC1","GO:0000276//mitochondrial proton-transporting ATP synthase complex, coupling factor F(o);GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0045263//proton-transporting ATP synthase complex, coupling factor F(o);GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion","GO:0008289//lipid binding;GO:0015078//hydrogen ion transmembrane transporter activity;GO:0005215//transporter activity;GO:0046933//proton-transporting ATP synthase activity, rotational mechanism","GO:0015986//ATP synthesis coupled proton transport;GO:0006754//ATP biosynthetic process;GO:0042407//cristae formation;GO:0015991//ATP hydrolysis coupled proton transport;GO:0042776//mitochondrial ATP synthesis coupled proton transport","K02128//F-type H+-transporting ATPase subunit c","NP_005166.1//ATP synthase F(0) complex subunit C1, mitochondrial precursor [Homo sapiens]","1//3;2//1"]
[59274,3068,16.99,21.29,0.325490097268074,{"v":5.84457127026264e-05,"d":"5.84E-05"},"*",{"v":1.295582E-5,"d":"1.30E-05"},"TLNRD1","GO:0001725//stress fiber","GO:0003779//actin binding","NA","K06271//talin","NP_072088.1//mesoderm development candidate 1 [Homo sapiens]","2//1"]
[7297,4262,14.91,18.68,0.32521419742622,{"v":7.55652887701945e-06,"d":"7.56E-06"},"*",{"v":1.434766e-06,"d":"1.43E-06"},"TYK2","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0031702//type 1 angiotensin receptor binding;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005524//ATP binding;GO:0005131//growth hormone receptor binding","GO:0060337//type I interferon signaling pathway;GO:0016477//cell migration;GO:0038083//peptidyl-tyrosine autophosphorylation;GO:0030154//cell differentiation;GO:0042127//regulation of cell proliferation;GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0060338//regulation of type I interferon-mediated signaling pathway;GO:0045087//innate immune response;GO:0035722//interleukin-12-mediated signaling pathway","K11219//non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]","NP_003322.3//non-receptor tyrosine-protein kinase TYK2 [Homo sapiens]",4]
[145553,760,10.81,13.53,0.323795316241887,0.154663900502882,"*",0.0789392,"MDP1","GO:0070062//extracellular exosome","GO:0046872//metal ion binding;GO:0004725//protein tyrosine phosphatase activity;GO:0016791//phosphatase activity","NA","K17619//magnesium-dependent phosphatase 1 [EC:3.1.3.48 3.1.3.-]","NP_612485.2//magnesium-dependent phosphatase 1 isoform 1 [Homo sapiens];NP_001186750.1//magnesium-dependent phosphatase 1 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[2647,590,60.51,75.7,0.323119715538976,0.00187300067685775,"*",0.000552262,"BLOC1S1","GO:0005759//mitochondrial matrix;GO:0005765//lysosomal membrane;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0099078//BORC complex;GO:0031083//BLOC-1 complex;GO:1904115//axon cytoplasm;GO:0005758//mitochondrial intermembrane space;GO:0005829//cytosol;GO:0005769//early endosome","NA","GO:0016197//endosomal transport;GO:0060155//platelet dense granule organization;GO:0018394//peptidyl-lysine acetylation;GO:0009060//aerobic respiration;GO:0048490//anterograde synaptic vesicle transport;GO:0031175//neuron projection development;GO:0008089//anterograde axonal transport;GO:0032418//lysosome localization;GO:0032438//melanosome organization","K20185//biogenesis of lysosome-related organelles complex 1 subunit 1","XP_008001755.1//PREDICTED: biogenesis of lysosome-related organelles complex 1 subunit 1 [Chlorocebus sabaeus]","3//A2MP1"]
[3780,2662,0.48,0.6,0.321928094887362,0.629890858297079,"*",0.507572,"KCNN1","NA","NA","NA","K04942//potassium intermediate/small conductance calcium-activated channel subfamily N member 1","XP_005259963.1//PREDICTED: small conductance calcium-activated potassium channel protein 1 isoform X2 [Homo sapiens]",4]
[25890,5756,0.04,0.05,0.321928094887362,0.78158613986014,"*",0.685686,"ABI3BP","GO:0031012//extracellular matrix;GO:0005615//extracellular space;GO:0005614//interstitial matrix;GO:0005576//extracellular region","GO:0005518//collagen binding;GO:0008201//heparin binding","GO:0030198//extracellular matrix organization;GO:0010811//positive regulation of cell-substrate adhesion","K10955//mucin-2;K08592//sentrin-specific protease 1 [EC:3.4.22.68]","NP_056244.2//target of Nesh-SH3 isoform 5 precursor [Homo sapiens];NP_001336259.1//target of Nesh-SH3 isoform 2 precursor [Homo sapiens];NP_001336260.1//target of Nesh-SH3 isoform 3 precursor [Homo sapiens];NP_001336258.1//target of Nesh-SH3 isoform 1 precursor [Homo sapiens];NP_001336261.1//target of Nesh-SH3 isoform 4 precursor [Homo sapiens]","1//3;3//A2MP1"]
[57414,1720,83.53,104.38,0.321478963915631,{"v":1.74981541086749e-08,"d":"1.75E-08"},"*",{"v":2.29818E-9,"d":"2.30E-09"},"RHBDD2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm;GO:0000139//Golgi membrane","GO:0004252//serine-type endopeptidase activity","NA","K09652//rhomboid domain-containing protein 2","XP_016814284.1//PREDICTED: rhomboid domain-containing protein 2 isoform X6 [Pan troglodytes];EAW71773.1//rhomboid domain containing 2, isoform CRA_a [Homo sapiens];NP_001333117.1//rhomboid domain-containing protein 2 isoform c [Homo sapiens];NP_001333118.1//rhomboid domain-containing protein 2 isoform d [Homo sapiens]","1//3;2//1"]
[23523,7197,10.84,13.53,0.319797082622665,{"v":1.44329857479735e-06,"d":"1.44E-06"},"*",{"v":2.45218e-07,"d":"2.45E-07"},"CABIN1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016235//aggresome","GO:0004864//protein phosphatase inhibitor activity","GO:0016569//covalent chromatin modification;GO:0006336//DNA replication-independent nucleosome assembly;GO:0007166//cell surface receptor signaling pathway","K17613//calcineurin-binding protein cabin-1","NP_001188358.1//calcineurin-binding protein cabin-1 isoform b [Homo sapiens];NP_036427.1//calcineurin-binding protein cabin-1 isoform a [Homo sapiens]","1//3;3//A2MP1"]
[843,5317,2.88,3.59,0.317915032380739,0.0354752352329361,"*",0.01434866,"CASP10","GO:0031265//CD95 death-inducing signaling complex;GO:0005829//cytosol;GO:0097342//ripoptosome","GO:0097199//cysteine-type endopeptidase activity involved in apoptotic signaling pathway;GO:0004197//cysteine-type endopeptidase activity;GO:0031625//ubiquitin protein ligase binding;GO:0035877//death effector domain binding;GO:0097200//cysteine-type endopeptidase activity involved in execution phase of apoptosis","GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0097194//execution phase of apoptosis;GO:0097190//apoptotic signaling pathway;GO:0007166//cell surface receptor signaling pathway;GO:0042981//regulation of apoptotic process;GO:0006915//apoptotic process","K04400//caspase 10 [EC:3.4.22.63]","NP_116756.2//caspase-10 isoform 2 preproprotein [Homo sapiens];NP_001293012.1//caspase-10 isoform 7 [Homo sapiens];XP_006712859.1//PREDICTED: caspase-10 isoform X2 [Homo sapiens];NP_001193453.1//caspase-10 isoform 6 preproprotein [Homo sapiens];NP_001221.2//caspase-10 isoform 3 preproprotein [Homo sapiens];NP_116759.2//caspase-10 isoform 1 preproprotein [Homo sapiens];NP_001193471.1//caspase-10 isoform 5 preproprotein [Homo sapiens]","4;1//3;3//A2MP1"]
[54663,1350,36.88,45.96,0.317540142216775,0.00027327236108325,"*",{"v":6.8224e-05,"d":"6.82E-05"},"WDR74","GO:0005634//nucleus;GO:0005730//nucleolus;GO:0030687//preribosome, large subunit precursor","NA","GO:0042273//ribosomal large subunit biogenesis","K14841//ribosome biogenesis protein NSA1","NP_060563.2//WD repeat-containing protein 74 isoform 1 [Homo sapiens];NP_001294906.1//WD repeat-containing protein 74 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[79574,2329,0.61,0.76,0.317190175880699,0.582918271029638,"*",0.426004,"EPS8L3","GO:0005737//cytoplasm","NA","GO:0042634//regulation of hair cycle","K17277//epidermal growth factor receptor kinase substrate 8","NP_078802.2//epidermal growth factor receptor kinase substrate 8-like protein 3 isoform c [Homo sapiens];XP_016857818.1//PREDICTED: epidermal growth factor receptor kinase substrate 8-like protein 3 isoform X6 [Homo sapiens];NP_620641.1//epidermal growth factor receptor kinase substrate 8-like protein 3 isoform a [Homo sapiens];NP_573444.2//epidermal growth factor receptor kinase substrate 8-like protein 3 isoform b [Homo sapiens]","1//3;3//A2MP1;2//1"]
[3459,2138,12.07,15.03,0.316419333161343,0.00887724364569962,"*",0.0030304,"IFNGR1","GO:0043231//intracellular membrane-bounded organelle;GO:0030425//dendrite;GO:0005783//endoplasmic reticulum;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0031982//vesicle;GO:0014069//postsynaptic density;GO:0005886//plasma membrane","GO:0004906//interferon-gamma receptor activity;GO:0019955//cytokine binding;GO:0004896//cytokine receptor activity","GO:0060333//interferon-gamma-mediated signaling pathway;GO:0007165//signal transduction;GO:0060334//regulation of interferon-gamma-mediated signaling pathway;GO:0051607//defense response to virus;GO:0019221//cytokine-mediated signaling pathway;GO:0009615//response to virus","K05132//interferon gamma receptor 1","NP_000407.1//interferon gamma receptor 1 precursor [Homo sapiens]","2//1"]
[79415,2255,29.21,36.35,0.315493005977778,{"v":6.4100298816933e-05,"d":"6.41E-05"},"*",{"v":1.431362e-05,"d":"1.43E-05"},"C17orf62","NA","NA","NA","K12740//NK-tumor recognition protein;K13172//serine/arginine repetitive matrix protein 2","BAC03465.1//FLJ00406 protein, partial [Homo sapiens]","1//3;3//A2MP1;2//1"]
[29880,1227,11.17,13.89,0.314417413498078,0.0743533768627451,"*",0.0332342,"ALG5","GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0004581//dolichyl-phosphate beta-glucosyltransferase activity;GO:0004576//oligosaccharyl transferase activity","GO:0006486//protein glycosylation;GO:0018279//protein N-linked glycosylation via asparagine;GO:0007368//determination of left/right symmetry;GO:0006487//protein N-linked glycosylation","K00729//dolichyl-phosphate beta-glucosyltransferase [EC:2.4.1.117]","XP_007958363.1//PREDICTED: dolichyl-phosphate beta-glucosyltransferase isoform X1 [Chlorocebus sabaeus]","1//3;4"]
[133957,1437,14.67,18.22,0.312654088128661,0.0222826258064516,"*",0.0084756,"CCDC127","NA","NA","NA","NA","XP_001139848.2//PREDICTED: coiled-coil domain-containing protein 127 [Pan troglodytes]","2//1"]
[11151,1832,1.37,1.7,0.311358853177175,0.491447801400382,"*",0.338328,"CORO1A","GO:0031252//cell leading edge;GO:0016020//membrane;GO:0005737//cytoplasm;GO:0045335//phagocytic vesicle;GO:0030864//cortical actin cytoskeleton;GO:0005911//cell-cell junction;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0005886//plasma membrane;GO:0005769//early endosome;GO:0030424//axon;GO:0070062//extracellular exosome;GO:0030670//phagocytic vesicle membrane;GO:0001772//immunological synapse;GO:0030027//lamellipodium;GO:0001891//phagocytic cup;GO:0005884//actin filament;GO:0043234//protein complex","GO:0043548//phosphatidylinositol 3-kinase binding;GO:0051015//actin filament binding;GO:0003723//RNA binding;GO:0042802//identical protein binding;GO:0008092//cytoskeletal protein binding;GO:0003785//actin monomer binding;GO:0042803//protein homodimerization activity;GO:0032036//myosin heavy chain binding;GO:0003779//actin binding;GO:0008022//protein C-terminus binding","GO:0030833//regulation of actin filament polymerization;GO:0032796//uropod organization;GO:0061502//early endosome to recycling endosome transport;GO:0030335//positive regulation of cell migration;GO:0051279//regulation of release of sequestered calcium ion into cytosol;GO:0042102//positive regulation of T cell proliferation;GO:0048873//homeostasis of number of cells within a tissue;GO:0032956//regulation of actin cytoskeleton organization;GO:0051126//negative regulation of actin nucleation;GO:0043320//natural killer cell degranulation;GO:0007015//actin filament organization;GO:0001845//phagolysosome assembly;GO:0071353//cellular response to interleukin-4;GO:0045087//innate immune response;GO:0006909//phagocytosis;GO:0030036//actin cytoskeleton organization;GO:0031339//negative regulation of vesicle fusion;GO:0030595//leukocyte chemotaxis;GO:0043524//negative regulation of neuron apoptotic process;GO:0006816//calcium ion transport;GO:0031589//cell-substrate adhesion;GO:0008360//regulation of cell shape;GO:0043029//T cell homeostasis;GO:0006928//movement of cell or subcellular component;GO:0038180//nerve growth factor signaling pathway;GO:0050918//positive chemotaxis","K13882//coronin-1A","XP_017374636.1//PREDICTED: coronin-1A isoform X1 [Cebus capucinus imitator];XP_008959819.1//PREDICTED: coronin-1A isoform X1 [Pan paniscus]","3//A2MP1;2//1"]
[2014,645,559.02,693.17,0.310309317694159,{"v":2.99976532495755e-24,"d":"3.00E-24"},"*",{"v":1.106086E-25,"d":"1.11E-25"},"EMP3","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","NA","GO:0032060//bleb assembly;GO:0008219//cell death;GO:0016049//cell growth;GO:0008285//negative regulation of cell proliferation","K19289//peripheral myelin protein 22","NP_001416.1//epithelial membrane protein 3 [Homo sapiens]","1//3;2//1"]
[51399,1286,16.72,20.72,0.309449155605671,0.0227868664676943,"*",0.00869878,"TRAPPC4","GO:0030425//dendrite;GO:0005783//endoplasmic reticulum;GO:0008021//synaptic vesicle;GO:0030008//TRAPP complex;GO:0000139//Golgi membrane;GO:0005795//Golgi stack;GO:0005829//cytosol;GO:0045202//synapse","GO:0017112//Rab guanyl-nucleotide exchange factor activity","GO:0006810//transport;GO:0016358//dendrite development;GO:0048208//COPII vesicle coating;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0016192//vesicle-mediated transport;GO:0061024//membrane organization","K20303//trafficking protein particle complex subunit 4","XP_008511651.1//PREDICTED: trafficking protein particle complex subunit 4 [Equus przewalskii];NP_001305418.1//trafficking protein particle complex subunit 4 isoform 4 [Homo sapiens];NP_001305423.1//trafficking protein particle complex subunit 4 isoform 7 [Homo sapiens];NP_001305419.1//trafficking protein particle complex subunit 4 isoform 5 [Homo sapiens]","1//3;5"]
[83743,2456,52.58,65.12,0.308586557648201,{"v":9.04701002345059E-10,"d":"9.05E-10"},"*",{"v":1.014348E-10,"d":"1.01E-10"},"GRWD1","GO:0005634//nucleus;GO:0005730//nucleolus;GO:0043234//protein complex;GO:0005829//cytosol;GO:0005694//chromosome","GO:0042393//histone binding;GO:0003688//DNA replication origin binding;GO:0003723//RNA binding;GO:0003682//chromatin binding","GO:0006260//DNA replication;GO:0006334//nucleosome assembly;GO:0006337//nucleosome disassembly","K14848//ribosome assembly protein RRB1","NP_113673.3//glutamate-rich WD repeat-containing protein 1 [Homo sapiens]","3//A2MP1"]
[25816,2147,5.57,6.89,0.30682665536426,0.0858303562380038,"*",0.0391916,"TNFAIP8","GO:0005737//cytoplasm","GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process","GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0042981//regulation of apoptotic process","K12471//epsin","NP_001071122.1//tumor necrosis factor alpha-induced protein 8 isoform b [Homo sapiens];XP_010337813.1//PREDICTED: tumor necrosis factor alpha-induced protein 8 isoform X1 [Saimiri boliviensis boliviensis];NP_001273743.1//tumor necrosis factor alpha-induced protein 8 isoform c [Homo sapiens];XP_021561633.1//tumor necrosis factor alpha-induced protein 8 isoform X2 [Carlito syrichta]","1//3;3//A2MP1;2//1"]
[55621,2118,21.36,26.41,0.306172654479539,0.000759572674157303,"*",0.000207368,"TRMT1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion","GO:0004809//tRNA (guanine-N2-)-methyltransferase activity;GO:0003723//RNA binding;GO:0046872//metal ion binding;GO:0000049//tRNA binding","GO:0002940//tRNA N2-guanine methylation;GO:0006400//tRNA modification","K00555//tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase [EC:2.1.1.215 2.1.1.216]","NP_001136026.1//tRNA (guanine(26)-N(2))-dimethyltransferase isoform 2 [Homo sapiens];NP_060192.1//tRNA (guanine(26)-N(2))-dimethyltransferase isoform 1 [Homo sapiens]","4;1//3;3//A2MP1;2//1"]
[10211,2025,55.99,69.19,0.305394360803594,{"v":7.07899657517659E-9,"d":"7.08E-09"},"*",{"v":8.78338e-10,"d":"8.78E-10"},"FLOT1","GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0044291//cell-cell contact zone;GO:0001931//uropod;GO:0042470//melanosome;GO:0034451//centriolar satellite;GO:0030864//cortical actin cytoskeleton;GO:0005901//caveola;GO:0005913//cell-cell adherens junction;GO:0008180//COP9 signalosome;GO:0005911//cell-cell junction;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005769//early endosome;GO:0070062//extracellular exosome;GO:0005765//lysosomal membrane;GO:0005815//microtubule organizing center;GO:0005925//focal adhesion;GO:0030027//lamellipodium;GO:0005768//endosome;GO:0045121//membrane raft;GO:0042383//sarcolemma;GO:0016600//flotillin complex","GO:0002020//protease binding;GO:0046982//protein heterodimerization activity;GO:0035255//ionotropic glutamate receptor binding","GO:0032226//positive regulation of synaptic transmission, dopaminergic;GO:0034976//response to endoplasmic reticulum stress;GO:0051260//protein homooligomerization;GO:0045807//positive regulation of endocytosis;GO:0001819//positive regulation of cytokine production;GO:0032092//positive regulation of protein binding;GO:1903044//protein localization to membrane raft;GO:1901890//positive regulation of cell junction assembly;GO:0001934//positive regulation of protein phosphorylation;GO:0001765//membrane raft assembly;GO:1901741//positive regulation of myoblast fusion;GO:0034116//positive regulation of heterotypic cell-cell adhesion;GO:0072659//protein localization to plasma membrane;GO:0032728//positive regulation of interferon-beta production;GO:0070528//protein kinase C signaling;GO:0071360//cellular response to exogenous dsRNA;GO:0034141//positive regulation of toll-like receptor 3 signaling pathway;GO:0044854//plasma membrane raft assembly;GO:0007409//axonogenesis;GO:0033227//dsRNA transport;GO:2000049//positive regulation of cell-cell adhesion mediated by cadherin;GO:0022617//extracellular matrix disassembly;GO:0048643//positive regulation of skeletal muscle tissue development;GO:0035023//regulation of Rho protein signal transduction;GO:0002090//regulation of receptor internalization;GO:0050821//protein stabilization;GO:0060355//positive regulation of cell adhesion molecule production","K07192//flotillin","NP_001305804.1//flotillin-1 isoform 2 [Homo sapiens];NP_005794.1//flotillin-1 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[55716,2294,3.53,4.36,0.304659951505746,0.271485675402699,"*",0.1561544,"LMBR1L","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004872//receptor activity","GO:0006898//receptor-mediated endocytosis","NA","NP_060583.2//protein LMBR1L isoform 1 [Homo sapiens];NP_001339090.1//protein LMBR1L isoform 4 [Homo sapiens];XP_016875117.1//PREDICTED: protein LMBR1L isoform X4 [Homo sapiens];NP_001339097.1//protein LMBR1L isoform 9 [Homo sapiens];NP_001287679.1//protein LMBR1L isoform 2 [Homo sapiens];NP_001339091.1//protein LMBR1L isoform 5 [Homo sapiens];NP_001287680.1//protein LMBR1L isoform 3 [Homo sapiens];EDL04155.1//limb region 1 like, isoform CRA_b, partial [Mus musculus]","1//3;3//A2MP1"]
[487,3569,0.64,0.79,0.303780748177103,0.641514756014806,"*",0.520794,"ATP2A1","GO:0016021//integral component of membrane","GO:0005524//ATP binding;GO:0005388//calcium-transporting ATPase activity","NA","K05853//Ca2+ transporting ATPase, sarcoplasmic/endoplasmic reticulum [EC:3.6.3.8]","XP_014981340.1//PREDICTED: sarcoplasmic/endoplasmic reticulum calcium ATPase 1 isoform X1 [Macaca mulatta];EDL17360.1//ATPase, Ca++ transporting, cardiac muscle, fast twitch 1, isoform CRA_d, partial [Mus musculus];XP_004586901.1//PREDICTED: sarcoplasmic/endoplasmic reticulum calcium ATPase 1 isoform X1 [Ochotona princeps]","1//3;4;3//A2MP1"]
[230,1665,5.77,7.12,0.303305922320915,0.162408812606474,"*",0.083553,"ALDOC","GO:0070062//extracellular exosome;GO:0005739//mitochondrion","GO:0008092//cytoskeletal protein binding;GO:0004332//fructose-bisphosphate aldolase activity","GO:0006096//glycolytic process;GO:0030388//fructose 1,6-bisphosphate metabolic process;GO:0030855//epithelial cell differentiation","K01623//fructose-bisphosphate aldolase, class I [EC:4.1.2.13]","XP_012304797.1//fructose-bisphosphate aldolase C isoform X1 [Aotus nancymaae]","2//1"]
[1072,1260,1621.29,1999.1,0.302208472442231,{"v":3.36003791701492e-135,"d":"3.36E-135"},"*",{"v":1.409306e-137,"d":"1.41E-137"},"CFL1","NA","NA","NA","K05765//cofilin","BAB32114.1//unnamed protein product [Mus musculus]","2//1"]
[6788,2828,5.53,6.81,0.300375317777364,0.155117811096142,"*",0.0792874,"STK3","GO:0005634//nucleus;GO:0043234//protein complex;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0000287//magnesium ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0042802//identical protein binding;GO:0043539//protein serine/threonine kinase activator activity;GO:0046983//protein dimerization activity","GO:0023014//signal transduction by protein phosphorylation;GO:0046330//positive regulation of JNK cascade;GO:0001841//neural tube formation;GO:0097284//hepatocyte apoptotic process;GO:0051897//positive regulation of protein kinase B signaling;GO:0007346//regulation of mitotic cell cycle;GO:0060800//regulation of cell differentiation involved in embryonic placenta development;GO:0035329//hippo signaling;GO:0035556//intracellular signal transduction;GO:0032092//positive regulation of protein binding;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0046621//negative regulation of organ growth;GO:0003157//endocardium development;GO:0031098//stress-activated protein kinase signaling cascade;GO:0008285//negative regulation of cell proliferation;GO:0060215//primitive hemopoiesis;GO:0007165//signal transduction;GO:0032147//activation of protein kinase activity;GO:0006468//protein phosphorylation;GO:0045600//positive regulation of fat cell differentiation;GO:0007417//central nervous system development;GO:0006915//apoptotic process;GO:1902043//positive regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0060706//cell differentiation involved in embryonic placenta development;GO:0042981//regulation of apoptotic process;GO:0050821//protein stabilization","K04412//serine/threonine kinase 3","XP_007999376.1//PREDICTED: serine/threonine-protein kinase 3 isoform X1 [Chlorocebus sabaeus];XP_011515550.2//PREDICTED: serine/threonine-protein kinase 3 isoform X2 [Homo sapiens];NP_001243242.1//serine/threonine-protein kinase 3 isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[56917,2011,22.01,27.09,0.299601248310457,0.00355096364072815,"*",1.11126E-3,"MEIS3","GO:0005634//nucleus","GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0043565//sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0051897//positive regulation of protein kinase B signaling;GO:0006355//regulation of transcription, DNA-templated;GO:2001234//negative regulation of apoptotic signaling pathway","K16671//homeobox protein Meis3","NP_001333077.1//homeobox protein Meis3 isoform 4 [Homo sapiens];NP_001287988.1//homeobox protein Meis3 isoform 3 [Homo sapiens];NP_064545.1//homeobox protein Meis3 isoform 1 [Homo sapiens];NP_001009813.1//homeobox protein Meis3 isoform 2 [Homo sapiens]","1//3;2//1"]
[252884,3658,0.26,0.32,0.299560281858908,0.647293726293103,"*",0.526458,"ZNF396","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity;GO:0003700//DNA binding transcription factor activity;GO:0042803//protein homodimerization activity","GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09229//KRAB and SCAN domains-containing zinc finger protein;K09230//SCAN domain-containing zinc finger protein","XP_003779011.1//PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 396 [Pongo abelii];NP_001309220.1//zinc finger protein 396 isoform 3 [Homo sapiens];XP_004623766.2//PREDICTED: zinc finger protein 345 isoform X1 [Octodon degus]","1//3;2//1"]
[970,2259,28.68,35.27,0.298396551724347,0.20897925203252,"*",0.11264,"CD70","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005164//tumor necrosis factor receptor binding;GO:0002020//protease binding;GO:0005125//cytokine activity;GO:0005102//receptor binding","GO:0007165//signal transduction;GO:0097191//extrinsic apoptotic signaling pathway;GO:0008283//cell proliferation;GO:0006955//immune response;GO:0007267//cell-cell signaling;GO:0033209//tumor necrosis factor-mediated signaling pathway","K05470//tumor necrosis factor ligand superfamily member 7","NP_001317261.1//CD70 antigen isoform 2 [Homo sapiens];XP_001088935.2//PREDICTED: CD70 antigen [Macaca mulatta]","4;1//3"]
[8904,2017,79.11,97.28,0.298283156857869,{"v":2.0963798573156e-10,"d":"2.10E-10"},"*",{"v":2.17066E-11,"d":"2.17E-11"},"CPNE1","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0005737//cytoplasm;GO:0035577//azurophil granule membrane;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0004175//endopeptidase activity;GO:0005544//calcium-dependent phospholipid binding;GO:0051059//NF-kappaB binding;GO:0005509//calcium ion binding;GO:0042803//protein homodimerization activity;GO:0001786//phosphatidylserine binding;GO:0005215//transporter activity","GO:0051897//positive regulation of protein kinase B signaling;GO:0045666//positive regulation of neuron differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0010629//negative regulation of gene expression;GO:0016192//vesicle-mediated transport;GO:0071277//cellular response to calcium ion;GO:1901223//negative regulation of NIK/NF-kappaB signaling;GO:1990138//neuron projection extension;GO:0043312//neutrophil degranulation;GO:1903265//positive regulation of tumor necrosis factor-mediated signaling pathway;GO:0006351//transcription, DNA-templated;GO:0046474//glycerophospholipid biosynthetic process;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043392//negative regulation of DNA binding;GO:0006508//proteolysis;GO:0006629//lipid metabolic process","K16280//E3 ubiquitin-protein ligase RGLG [EC:2.3.2.27];K20493//leucine-rich repeat-containing protein 16","NP_003906.2//copine-1 isoform b [Homo sapiens];XP_017827294.1//PREDICTED: copine-1 isoform X5 [Callithrix jacchus];NP_690902.1//copine-1 isoform a [Homo sapiens];NP_001185792.1//copine-1 isoform c [Homo sapiens]","1//3;2//1;5"]
[93100,1721,9.17,11.27,0.297493876577167,0.0678423572749253,"*",0.029861,"NAPRT","GO:0070062//extracellular exosome;GO:0035578//azurophil granule lumen;GO:0005829//cytosol;GO:0005576//extracellular region","GO:0004516//nicotinate phosphoribosyltransferase activity;GO:0004514//nicotinate-nucleotide diphosphorylase (carboxylating) activity;GO:0016874//ligase activity","GO:0006979//response to oxidative stress;GO:0019358//nicotinate nucleotide salvage;GO:0034356//NAD biosynthesis via nicotinamide riboside salvage pathway;GO:0043312//neutrophil degranulation","K00763//nicotinate phosphoribosyltransferase [EC:6.3.4.21]","NP_001273758.1//nicotinate phosphoribosyltransferase isoform 2 [Homo sapiens];NP_660202.3//nicotinate phosphoribosyltransferase isoform 1 [Homo sapiens]","1//3;5"]
[1201,1868,33.14,40.7,0.296455191932158,{"v":6.60021022147651e-05,"d":"6.60E-05"},"*",{"v":1.477548E-5,"d":"1.48E-05"},"CLN3","GO:0005783//endoplasmic reticulum;GO:0005770//late endosome;GO:0005737//cytoplasm;GO:0000139//Golgi membrane;GO:0005795//Golgi stack;GO:0005901//caveola;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0005776//autophagosome;GO:0005769//early endosome;GO:0005765//lysosomal membrane;GO:0005634//nucleus;GO:0008021//synaptic vesicle;GO:0005764//lysosome;GO:0005802//trans-Golgi network;GO:0043005//neuron projection;GO:0045121//membrane raft;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005794//Golgi apparatus","GO:0051082//unfolded protein binding;GO:0048306//calcium-dependent protein binding","GO:0035752//lysosomal lumen pH elevation;GO:0016477//cell migration;GO:0042987//amyloid precursor protein catabolic process;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0006672//ceramide metabolic process;GO:0097352//autophagosome maturation;GO:0016485//protein processing;GO:0051489//regulation of filopodium assembly;GO:0030036//actin cytoskeleton organization;GO:0006520//cellular amino acid metabolic process;GO:0043524//negative regulation of neuron apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0015809//arginine transport;GO:0042133//neurotransmitter metabolic process;GO:0006865//amino acid transport;GO:0006898//receptor-mediated endocytosis;GO:0006681//galactosylceramide metabolic process;GO:0001508//action potential;GO:0007042//lysosomal lumen acidification;GO:0050885//neuromuscular process controlling balance;GO:0016236//macroautophagy;GO:0001575//globoside metabolic process;GO:0045861//negative regulation of proteolysis;GO:0006678//glucosylceramide metabolic process;GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0001934//positive regulation of protein phosphorylation;GO:0006897//endocytosis;GO:0043086//negative regulation of catalytic activity;GO:0007040//lysosome organization;GO:0006684//sphingomyelin metabolic process;GO:0047496//vesicle transport along microtubule;GO:0072659//protein localization to plasma membrane;GO:0030163//protein catabolic process;GO:0007034//vacuolar transport;GO:0061024//membrane organization;GO:0008306//associative learning","K12389//battenin","NP_000077.1//battenin isoform a [Homo sapiens];XP_011943818.1//PREDICTED: battenin isoform X2 [Cercocebus atys];NP_001273033.1//battenin isoform b [Homo sapiens]","1//3;2//1"]
[51710,2773,0.57,0.7,0.296393002780225,0.593888752977203,"*",0.43707,"ZNF44","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","XP_512401.4//PREDICTED: zinc finger protein 44 isoform X10 [Pan troglodytes];XP_015296246.1//PREDICTED: zinc finger protein 44 isoform X1 [Macaca fascicularis];NP_057348.3//zinc finger protein 44 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[11331,1453,224.75,275.74,0.29498745017844,{"v":5.07287639831697e-21,"d":"5.07E-21"},"*",{"v":2.26428E-22,"d":"2.26E-22"},"PHB2","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0030424//axon;GO:0005634//nucleus;GO:0071944//cell periphery;GO:0016363//nuclear matrix;GO:0005741//mitochondrial outer membrane;GO:0005737//cytoplasm;GO:0009986//cell surface;GO:0043234//protein complex;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0030331//estrogen receptor binding;GO:0008022//protein C-terminus binding;GO:0047485//protein N-terminus binding;GO:0033218//amide binding","GO:0071456//cellular response to hypoxia;GO:0043433//negative regulation of DNA binding transcription factor activity;GO:0000060//protein import into nucleus, translocation;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0031536//positive regulation of exit from mitosis;GO:0033147//negative regulation of intracellular estrogen receptor signaling pathway;GO:0009611//response to wounding;GO:0006851//mitochondrial calcium ion transmembrane transport;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0060744//mammary gland branching involved in thelarche;GO:0043066//negative regulation of apoptotic process;GO:0007005//mitochondrion organization;GO:0060762//regulation of branching involved in mammary gland duct morphogenesis;GO:0071300//cellular response to retinoic acid;GO:0060749//mammary gland alveolus development;GO:0007062//sister chromatid cohesion;GO:1902808//positive regulation of cell cycle G1/S phase transition;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0050821//protein stabilization;GO:0033600//negative regulation of mammary gland epithelial cell proliferation","K17081//prohibitin 2","NP_031557.2//prohibitin-2 [Mus musculus];NP_001254629.1//prohibitin-2 isoform 3 [Homo sapiens]","1//3"]
[5625,2151,1.24,1.52,0.29373120305671,0.673883572794899,"*",0.555762,"PRODH","GO:0005759//mitochondrial matrix;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0004657//proline dehydrogenase activity;GO:0071949//FAD binding","GO:0008631//intrinsic apoptotic signaling pathway in response to oxidative stress;GO:0006562//proline catabolic process;GO:0019470//4-hydroxyproline catabolic process;GO:0010133//proline catabolic process to glutamate;GO:0006560//proline metabolic process;GO:0010942//positive regulation of cell death","K00318//proline dehydrogenase [EC:1.5.-.-]","NP_057419.4//proline dehydrogenase 1, mitochondrial isoform 1 precursor [Homo sapiens]","4;1//3"]
[91074,4405,0.31,0.38,0.29373120305671,0.639663265621379,"*",0.51845,"ANKRD30A","GO:0005634//nucleus","GO:0003677//DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0006355//regulation of transcription, DNA-templated","K17299//POTE ankyrin domain family protein","Q9BXX3.3//RecName: Full=Ankyrin repeat domain-containing protein 30A; AltName: Full=Serologically defined breast cancer antigen NY-BR-1","2//1"]
[100128124,1016,0.4,0.49,0.292781749227846,0.846805230853767,"*",0.771794,"HGC6","NA","NA","NA","K10385//loricrin;K02184//formin 2","NP_001123367.1//uncharacterized protein LOC100128124 [Homo sapiens]","2//1"]
[9454,1424,21.7,26.58,0.292646061944333,0.00878719618732782,"*",2.99526E-3,"HOMER3","GO:0005829//cytosol;GO:0030054//cell junction;GO:0014069//postsynaptic density;GO:0045211//postsynaptic membrane;GO:0045178//basal part of cell","GO:0019904//protein domain specific binding;GO:0008022//protein C-terminus binding;GO:0035256//G-protein coupled glutamate receptor binding;GO:0042802//identical protein binding","GO:0006605//protein targeting;GO:0007216//G-protein coupled glutamate receptor signaling pathway","K15010//homer","NP_001139196.1//homer protein homolog 3 isoform 3 [Homo sapiens];NP_001139193.1//homer protein homolog 3 isoform 2 [Homo sapiens];NP_004829.3//homer protein homolog 3 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[65057,2093,26.83,32.84,0.291607072517284,0.000239486811364789,"*",{"v":5.90996e-05,"d":"5.91E-05"},"ACD","GO:0005654//nucleoplasm;GO:0000784//nuclear chromosome, telomeric region;GO:0016604//nuclear body;GO:0000783//nuclear telomere cap complex;GO:0070187//shelterin complex","GO:0042162//telomeric DNA binding;GO:0070182//DNA polymerase binding;GO:0044877//macromolecular complex binding","GO:0032202//telomere assembly;GO:0070200//establishment of protein localization to telomere;GO:0070198//protein localization to chromosome, telomeric region;GO:0001655//urogenital system development;GO:0051973//positive regulation of telomerase activity;GO:0035282//segmentation;GO:0031848//protection from non-homologous end joining at telomere;GO:0030326//embryonic limb morphogenesis;GO:0016233//telomere capping;GO:0006886//intracellular protein transport;GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0060381//positive regulation of single-stranded telomeric DNA binding;GO:0001501//skeletal system development;GO:0032211//negative regulation of telomere maintenance via telomerase;GO:0000723//telomere maintenance","K11114//adrenocortical dysplasia protein","NP_075065.2//adrenocortical dysplasia protein homolog isoform 2 [Homo sapiens];NP_001075955.1//adrenocortical dysplasia protein homolog isoform 1 [Homo sapiens];NP_001075956.1//adrenocortical dysplasia protein homolog isoform 3 [Homo sapiens]","1//3;2//1"]
[1760,2723,33.48,40.96,0.290916187449656,{"v":5.94092967457401e-06,"d":"5.94E-06"},"*",{"v":1.113134e-06,"d":"1.11E-06"},"DMPK","GO:0031965//nuclear membrane;GO:0031307//integral component of mitochondrial outer membrane;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0033017//sarcoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005640//nuclear outer membrane","GO:0046872//metal ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0017020//myosin phosphatase regulator activity;GO:0031072//heat shock protein binding","GO:1903779//regulation of cardiac conduction;GO:0014722//regulation of skeletal muscle contraction by calcium ion signaling;GO:0002028//regulation of sodium ion transport;GO:0006468//protein phosphorylation;GO:0051823//regulation of synapse structural plasticity;GO:0014853//regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction;GO:0010830//regulation of myotube differentiation;GO:0010657//muscle cell apoptotic process;GO:0018105//peptidyl-serine phosphorylation;GO:0008016//regulation of heart contraction;GO:0006874//cellular calcium ion homeostasis;GO:0006998//nuclear envelope organization","K08788//dystrophia myotonica-protein kinase [EC:2.7.11.1]","NP_001075029.1//myotonin-protein kinase isoform 3 [Homo sapiens];NP_001075031.1//myotonin-protein kinase isoform 4 [Homo sapiens];NP_004400.4//myotonin-protein kinase isoform 2 [Homo sapiens];NP_001275693.1//myotonin-protein kinase isoform 5 [Homo sapiens];NP_001075032.1//myotonin-protein kinase isoform 1 [Homo sapiens];AAC14450.1//myotonic dystrophy kinase [Homo sapiens];XP_014198194.1//PREDICTED: myotonin-protein kinase isoform X1 [Pan paniscus]","1//3;4;2//1"]
[51083,830,8.12,9.93,0.290313990343198,0.301274998226685,"*",0.1765516,"GAL","GO:0030141//secretory granule;GO:0005615//extracellular space;GO:0005794//Golgi apparatus;GO:0005622//intracellular;GO:0005576//extracellular region;GO:0043025//neuronal cell body","GO:0031765//type 2 galanin receptor binding;GO:0031764//type 1 galanin receptor binding;GO:0031763//galanin receptor binding;GO:0031766//type 3 galanin receptor binding;GO:0005184//neuropeptide hormone activity;GO:0004966//galanin receptor activity","GO:0007399//nervous system development;GO:0050672//negative regulation of lymphocyte proliferation;GO:0043627//response to estrogen;GO:0051464//positive regulation of cortisol secretion;GO:0030073//insulin secretion;GO:0043065//positive regulation of apoptotic process;GO:0007218//neuropeptide signaling pathway;GO:1902608//positive regulation of large conductance calcium-activated potassium channel activity;GO:0042493//response to drug;GO:0010737//protein kinase A signaling;GO:0032868//response to insulin;GO:0031943//regulation of glucocorticoid metabolic process;GO:0035902//response to immobilization stress;GO:0019933//cAMP-mediated signaling;GO:0006954//inflammatory response;GO:1902891//negative regulation of root hair elongation;GO:0007631//feeding behavior;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0051795//positive regulation of timing of catagen","K05244//galanin","EAW74716.1//galanin, isoform CRA_b, partial [Homo sapiens]",4]
[4736,719,467.46,571.61,0.29018823523302,{"v":2.50718788058124e-20,"d":"2.51E-20"},"*",{"v":1.188144e-21,"d":"1.19E-21"},"RPL10A","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0015934//large ribosomal subunit;GO:0005925//focal adhesion;GO:0022625//cytosolic large ribosomal subunit;GO:0005829//cytosol;GO:0005739//mitochondrion","GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome","GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006364//rRNA processing;GO:0045471//response to ethanol;GO:0000470//maturation of LSU-rRNA;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006413//translational initiation;GO:0006412//translation;GO:0019083//viral transcription","K02865//large subunit ribosomal protein L10Ae","XP_002749582.2//PREDICTED: 60S ribosomal protein L10a-like [Callithrix jacchus]",4]
[8809,3661,0.09,0.11,0.289506617194985,0.830555166459112,"*",0.751524,"IL18R1","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004872//receptor activity;GO:0042008//interleukin-18 receptor activity;GO:0004908//interleukin-1 receptor activity","GO:0045063//T-helper 1 cell differentiation;GO:0030101//natural killer cell activation;GO:0007165//signal transduction;GO:0006955//immune response;GO:0042346//positive regulation of NF-kappaB import into nucleus;GO:0032729//positive regulation of interferon-gamma production","K05173//interleukin 18 receptor 1","NP_003846.1//interleukin-18 receptor 1 isoform 1 precursor [Homo sapiens];XP_005264096.1//PREDICTED: interleukin-18 receptor 1 isoform X1 [Homo sapiens]","1//3;3//A2MP1"]
[55505,552,496.07,606.19,0.289226340530441,{"v":2.93188841931034e-16,"d":"2.93E-16"},"*",{"v":1.862944e-17,"d":"1.86E-17"},"NOP10","GO:0005654//nucleoplasm;GO:0072589//box H/ACA scaRNP complex;GO:0005732//small nucleolar ribonucleoprotein complex;GO:0090661//box H/ACA telomerase RNP complex;GO:0031429//box H/ACA snoRNP complex;GO:0016604//nuclear body;GO:0030529//intracellular ribonucleoprotein complex;GO:0005697//telomerase holoenzyme complex;GO:0019013//viral nucleocapsid","GO:0030515//snoRNA binding;GO:0003723//RNA binding;GO:0034513//box H/ACA snoRNA binding;GO:0070034//telomerase RNA binding","GO:0031120//snRNA pseudouridine synthesis;GO:1904874//positive regulation of telomerase RNA localization to Cajal body;GO:0042254//ribosome biogenesis;GO:0007004//telomere maintenance via telomerase;GO:0031118//rRNA pseudouridine synthesis;GO:0001522//pseudouridine synthesis;GO:0000454//snoRNA guided rRNA pseudouridine synthesis","K11130//H/ACA ribonucleoprotein complex subunit 3","NP_061118.1//H/ACA ribonucleoprotein complex subunit 3 [Homo sapiens]","3//A2MP1"]
[51374,1035,144.69,176.71,0.28841846822413,{"v":2.31406236973995e-08,"d":"2.31E-08"},"*",{"v":3.06388E-9,"d":"3.06E-09"},"ATRAID","GO:0005765//lysosomal membrane;GO:0005635//nuclear envelope;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0048471//perinuclear region of cytoplasm","NA","GO:0033689//negative regulation of osteoblast proliferation;GO:0010468//regulation of gene expression;GO:0030501//positive regulation of bone mineralization;GO:0030154//cell differentiation;GO:1903363//negative regulation of cellular protein catabolic process;GO:0045669//positive regulation of osteoblast differentiation","K14386//solute carrier family 5 (sodium-dependent multivitamin transporter), member 6","NP_542159.3//all-trans retinoic acid-induced differentiation factor isoform b [Homo sapiens]","1//3;4;3//A2MP1"]
[80148,2480,10.36,12.65,0.288113381895119,0.0227781639573421,"*",0.00869118,"PQLC1","GO:0016021//integral component of membrane","NA","NA","K11448//lysine-specific demethylase 6B [EC:1.14.11.-]","NP_001139817.1//PQ-loop repeat-containing protein 1 isoform 3 [Homo sapiens];XP_022369390.1//PQ-loop repeat-containing protein 1 isoform X3 [Enhydra lutris kenyoni];NP_079354.2//PQ-loop repeat-containing protein 1 isoform 1 [Homo sapiens]","1//3;4"]
[9245,2240,57.98,70.73,0.286766927903848,{"v":1.42342946124819e-08,"d":"1.42E-08"},"*",{"v":1.841886e-09,"d":"1.84E-09"},"GCNT3","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0047225//acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity;GO:0008109//N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity;GO:0003829//beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity","GO:0048729//tissue morphogenesis;GO:0006493//protein O-linked glycosylation;GO:0002426//immunoglobulin production in mucosal tissue;GO:0060993//kidney morphogenesis;GO:0005975//carbohydrate metabolic process;GO:0050892//intestinal absorption;GO:0016266//O-glycan processing","K09662//N-acetylglucosaminyltransferase 3, mucin type [EC:2.4.1.-]","NP_004742.1//beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 [Homo sapiens]","2//1"]
[3108,1122,4.01,4.89,0.286232228497313,0.418523374892601,"*",0.274448,"HLA-DMA","GO:0070062//extracellular exosome;GO:0043231//intracellular membrane-bounded organelle;GO:0009986//cell surface;GO:0042613//MHC class II protein complex;GO:0016021//integral component of membrane","GO:0023026//MHC class II protein complex binding","GO:0002503//peptide antigen assembly with MHC class II protein complex;GO:0006955//immune response;GO:0002504//antigen processing and presentation of peptide or polysaccharide antigen via MHC class II","K06752//major histocompatibility complex, class II","NP_006111.2//HLA class II histocompatibility antigen, DM alpha chain precursor [Homo sapiens]","3//A2MP1"]
[9409,1929,7.96,9.7,0.285216316530841,0.0863924435508138,"*",0.0395402,"PEX16","GO:0016020//membrane;GO:0005779//integral component of peroxisomal membrane;GO:0005783//endoplasmic reticulum;GO:0005777//peroxisome;GO:0005789//endoplasmic reticulum membrane;GO:0005778//peroxisomal membrane","GO:0008022//protein C-terminus binding","GO:0007031//peroxisome organization;GO:0016557//peroxisome membrane biogenesis;GO:0032581//ER-dependent peroxisome organization;GO:0070972//protein localization to endoplasmic reticulum;GO:0022615//protein to membrane docking;GO:0016558//protein import into peroxisome matrix;GO:0045046//protein import into peroxisome membrane;GO:0006625//protein targeting to peroxisome","K13335//peroxin-16","XP_010369352.1//PREDICTED: peroxisomal biogenesis factor 16 isoform X3 [Rhinopithecus roxellana];XP_019512030.1//PREDICTED: peroxisomal biogenesis factor 16 [Hipposideros armiger]","2//1"]
[2010,1370,92.9,113.16,0.284613580126237,{"v":3.37399428650392e-08,"d":"3.37E-08"},"*",{"v":4.58554e-09,"d":"4.59E-09"},"EMD","GO:0016020//membrane;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0005783//endoplasmic reticulum;GO:0005874//microtubule;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0032541//cortical endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005637//nuclear inner membrane;GO:0031616//spindle pole centrosome;GO:0005640//nuclear outer membrane","GO:0003779//actin binding;GO:0048487//beta-tubulin binding;GO:0045296//cadherin binding","GO:0046827//positive regulation of protein export from nucleus;GO:0007077//mitotic nuclear envelope disassembly;GO:0006936//muscle contraction;GO:0007517//muscle organ development;GO:0048147//negative regulation of fibroblast proliferation;GO:0007084//mitotic nuclear envelope reassembly;GO:0035914//skeletal muscle cell differentiation;GO:0060828//regulation of canonical Wnt signaling pathway;GO:0035414//negative regulation of catenin import into nucleus;GO:0071363//cellular response to growth factor stimulus","K12569//emerin","NP_000108.1//emerin [Homo sapiens]","2//1"]
[51116,1516,99.03,120.58,0.284053090094075,{"v":1.69158166504065e-09,"d":"1.69E-09"},"*",{"v":1.95378e-10,"d":"1.95E-10"},"MRPS2","GO:0005763//mitochondrial small ribosomal subunit;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0015935//small ribosomal subunit","GO:0003735//structural constituent of ribosome","GO:0032543//mitochondrial translation;GO:0006412//translation;GO:0070126//mitochondrial translational termination;GO:0070125//mitochondrial translational elongation","K02967//small subunit ribosomal protein S2","XP_006717199.1//PREDICTED: 28S ribosomal protein S2, mitochondrial isoform X1 [Homo sapiens]",4]
[598,2520,145.92,177.6,0.283453947072727,{"v":5.71877476683938e-20,"d":"5.72E-20"},"*",{"v":2.7638E-21,"d":"2.76E-21"},"BCL2L1","GO:0005759//mitochondrial matrix;GO:0097136//Bcl-2 family protein complex;GO:0031965//nuclear membrane;GO:0005783//endoplasmic reticulum;GO:0005813//centrosome;GO:0030054//cell junction;GO:0005741//mitochondrial outer membrane;GO:0005737//cytoplasm;GO:0030672//synaptic vesicle membrane;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0042802//identical protein binding;GO:0051434//BH3 domain binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0019901//protein kinase binding","GO:0090201//negative regulation of release of cytochrome c from mitochondria;GO:0008584//male gonad development;GO:0043065//positive regulation of apoptotic process;GO:0046898//response to cycloheximide;GO:0070584//mitochondrion morphogenesis;GO:1903077//negative regulation of protein localization to plasma membrane;GO:0046902//regulation of mitochondrial membrane permeability;GO:0043524//negative regulation of neuron apoptotic process;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway;GO:0000910//cytokinesis;GO:0043066//negative regulation of apoptotic process;GO:0001541//ovarian follicle development;GO:0006915//apoptotic process;GO:0007093//mitotic cell cycle checkpoint;GO:0007281//germ cell development;GO:0071839//apoptotic process in bone marrow;GO:0097284//hepatocyte apoptotic process;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0051402//neuron apoptotic process;GO:0019050//suppression by virus of host apoptotic process;GO:0034097//response to cytokine;GO:0008637//apoptotic mitochondrial changes;GO:0007283//spermatogenesis;GO:1902230//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage;GO:0008283//cell proliferation;GO:0006897//endocytosis;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0001836//release of cytochrome c from mitochondria;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0060154//cellular process regulating host cell cycle in response to virus;GO:0009566//fertilization;GO:1900118//negative regulation of execution phase of apoptosis;GO:0001701//in utero embryonic development;GO:0071480//cellular response to gamma radiation;GO:0071230//cellular response to amino acid stimulus;GO:2000811//negative regulation of anoikis;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway;GO:0010507//negative regulation of autophagy;GO:0040007//growth;GO:0042981//regulation of apoptotic process;GO:0051881//regulation of mitochondrial membrane potential;GO:0071312//cellular response to alkaloid;GO:0008284//positive regulation of cell proliferation","K04570//Bcl-2-like 1 (apoptosis regulator Bcl-X)","EDL05992.1//Bcl2-like 1, isoform CRA_c, partial [Mus musculus];NP_001182.1//bcl-2-like protein 1 isoform Bcl-X(S) [Homo sapiens]","1//3;3//A2MP1;2//1"]
[4155,4605,8.82,10.73,0.282799515199001,0.00143639789103538,"*",0.000414266,"MBP","GO:0033269//internode region of axon;GO:0005634//nucleus;GO:0043218//compact myelin;GO:0043234//protein complex;GO:0043209//myelin sheath;GO:0005622//intracellular;GO:0071944//cell periphery;GO:0005886//plasma membrane;GO:0043025//neuronal cell body","GO:0002020//protease binding;GO:0005516//calmodulin binding;GO:0019911//structural constituent of myelin sheath","GO:1904209//positive regulation of chemokine (C-C motif) ligand 2 secretion;GO:0042552//myelination;GO:0021762//substantia nigra development;GO:0000165//MAPK cascade;GO:0035633//maintenance of permeability of blood-brain barrier;GO:0007417//central nervous system development;GO:0009636//response to toxic substance;GO:0061024//membrane organization;GO:0008366//axon ensheathment;GO:0034115//negative regulation of heterotypic cell-cell adhesion;GO:0007605//sensory perception of sound;GO:1904685//positive regulation of metalloendopeptidase activity;GO:0007268//chemical synaptic transmission;GO:0006955//immune response;GO:2000778//positive regulation of interleukin-6 secretion","K17269//myelin basic protein","BAD92223.1//Myelin basic protein variant, partial [Homo sapiens];NP_001020272.1//Golli-MBP isoform 1 [Homo sapiens];EAW66598.1//myelin basic protein, isoform CRA_g [Homo sapiens];EAW66595.1//myelin basic protein, isoform CRA_d [Homo sapiens];EAW66596.1//myelin basic protein, isoform CRA_e [Homo sapiens]","1//3;2//1"]
[51754,3388,3.1,3.77,0.282296307994427,0.505589549328768,"*",0.351292,"TMEM8B","GO:0016021//integral component of membrane","NA","NA","K04953//cyclic nucleotide gated channel beta 3;K11661//helicase SRCAP [EC:3.6.4.-]","XP_011746507.1//PREDICTED: transmembrane protein 8B isoform X2 [Macaca nemestrina];AAF34820.1//NAG-5 protein [Homo sapiens];XP_017713268.1//PREDICTED: transmembrane protein 8B isoform X2 [Rhinopithecus bieti]","3//A2MP1;2//1"]
[122769,1503,21.47,26.1,0.281727615598474,0.071562350731982,"*",0.0318254,"LRR1","GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005737//cytoplasm","NA","GO:0043687//post-translational protein modification;GO:0007165//signal transduction;GO:0016567//protein ubiquitination","K10348//LRR-repeat protein 1","NP_982292.1//leucine-rich repeat protein 1 isoform 3 [Homo sapiens];CAD62625.1//unnamed protein product, partial [Homo sapiens]","1//3;3//A2MP1"]
[746,420,143.34,174.12,0.280640665610412,0.000537616568595041,"*",0.000142532,"TMEM258","NA","NA","NA","NA","XP_021007951.1//transmembrane protein 258 [Mus caroli]","3//A2MP1"]
[10318,2814,52.36,63.55,0.27942702794708,{"v":1.2290820952381E-8,"d":"1.23E-08"},"*",{"v":1.58348E-9,"d":"1.58E-09"},"TNIP1","GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005737//cytoplasm","GO:0031593//polyubiquitin modification-dependent protein binding;GO:0051019//mitogen-activated protein kinase binding;GO:0042802//identical protein binding","GO:0007159//leukocyte cell-cell adhesion;GO:0009101//glycoprotein biosynthetic process;GO:1903003//positive regulation of protein deubiquitination;GO:0071222//cellular response to lipopolysaccharide;GO:0050729//positive regulation of inflammatory response;GO:0085032//modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade;GO:0045071//negative regulation of viral genome replication;GO:0016579//protein deubiquitination;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0006954//inflammatory response;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0050727//regulation of inflammatory response;GO:0006952//defense response;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006412//translation;GO:0002755//MyD88-dependent toll-like receptor signaling pathway","K10352//myosin heavy chain;K14000//ribosome-binding protein 1;K12478//early endosome antigen 1;K20478//golgin subfamily B member 1","NP_001245385.1//TNFAIP3-interacting protein 1 isoform 6 [Homo sapiens];BAH12846.1//unnamed protein product [Homo sapiens];NP_001239321.1//TNFAIP3-interacting protein 1 isoform 4 [Homo sapiens];NP_006049.3//TNFAIP3-interacting protein 1 isoform 3 [Homo sapiens];NP_001239314.1//TNFAIP3-interacting protein 1 isoform 1 [Homo sapiens];NP_001245384.1//TNFAIP3-interacting protein 1 isoform 5 [Homo sapiens]","4;1//3"]
[3487,2246,1554.22,1885.84,0.279016547046187,{"v":5.27681243515151e-199,"d":"5.28E-199"},"*",{"v":1.090114E-201,"d":"1.09E-201"},"IGFBP4","GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0005576//extracellular region","GO:0005520//insulin-like growth factor binding;GO:0031994//insulin-like growth factor I binding;GO:0005102//receptor binding;GO:0031995//insulin-like growth factor II binding","GO:0001558//regulation of cell growth;GO:0043687//post-translational protein modification;GO:0007165//signal transduction;GO:0043567//regulation of insulin-like growth factor receptor signaling pathway;GO:0006259//DNA metabolic process;GO:0043568//positive regulation of insulin-like growth factor receptor signaling pathway;GO:0006954//inflammatory response;GO:0044267//cellular protein metabolic process;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0008283//cell proliferation;GO:0044342//type B pancreatic cell proliferation;GO:0010906//regulation of glucose metabolic process;GO:0043410//positive regulation of MAPK cascade;GO:0001501//skeletal system development","K10138//insulin-like growth factor-binding protein 3","NP_001543.2//insulin-like growth factor-binding protein 4 precursor [Homo sapiens]","2//1"]
[113000,1895,49.03,59.47,0.278497314090518,{"v":1.36673523773346E-5,"d":"1.37E-05"},"*",{"v":2.70284E-6,"d":"2.70E-06"},"RPUSD1","NA","GO:0003723//RNA binding;GO:0009982//pseudouridine synthase activity","GO:0031119//tRNA pseudouridine synthesis;GO:0000455//enzyme-directed rRNA pseudouridine synthesis;GO:0001522//pseudouridine synthesis","K01855//tRNA pseudouridine38/39 synthase [EC:5.4.99.45]","AAH12951.2//RPUSD1 protein, partial [Homo sapiens];NP_001311015.1//RNA pseudouridylate synthase domain-containing protein 1 isoform 2 [Homo sapiens];NP_478072.1//RNA pseudouridylate synthase domain-containing protein 1 isoform 1 [Homo sapiens]","1//3;2//1"]
[353514,1327,1.74,2.11,0.278155692858457,0.602528402473109,"*",0.445352,"LILRA5","GO:0070062//extracellular exosome;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","NA","GO:0045087//innate immune response","K06512//leukocyte immunoglobulin-like receptor","NP_871715.1//leukocyte immunoglobulin-like receptor subfamily A member 5 isoform 4 [Homo sapiens];NP_870994.1//leukocyte immunoglobulin-like receptor subfamily A member 5 isoform 3 [Homo sapiens];NP_067073.1//leukocyte immunoglobulin-like receptor subfamily A member 5 isoform 1 precursor [Homo sapiens];NP_871714.1//leukocyte immunoglobulin-like receptor subfamily A member 5 isoform 2 [Homo sapiens]","3//A2MP1;2//1"]
[4943,3918,7.8,9.45,0.276840205358824,0.0167746633458518,"*",6.15162E-3,"TBC1D25","GO:0012505//endomembrane system;GO:0031410//cytoplasmic vesicle;GO:0005776//autophagosome","GO:0008483//transaminase activity;GO:0017137//Rab GTPase binding;GO:0005096//GTPase activator activity","GO:0006886//intracellular protein transport;GO:0090630//activation of GTPase activity;GO:0031338//regulation of vesicle fusion;GO:0006914//autophagy;GO:1901096//regulation of autophagosome maturation;GO:0061024//membrane organization","K20168//TBC1 domain family member 15","NP_001335192.1//TBC1 domain family member 25 isoform b [Homo sapiens];NP_002527.1//TBC1 domain family member 25 isoform c [Homo sapiens];NP_001335191.1//TBC1 domain family member 25 isoform a [Homo sapiens];NP_001335194.1//TBC1 domain family member 25 isoform d [Homo sapiens]","1//3;3//A2MP1"]
[84182,2750,2.75,3.33,0.27609055865924,0.283632352867345,"*",0.1640998,"MINDY4","NA","GO:0036459//thiol-dependent ubiquitinyl hydrolase activity","NA","K08742//E3 ubiquitin-protein ligase SIAH2 [EC:2.3.2.27];K20465//oxysterol-binding protein-related protein 9/10/11","NP_115598.2//probable ubiquitin carboxyl-terminal hydrolase MINDY-4 [Homo sapiens]","2//1"]
[55283,2746,1.71,2.07,0.275634442613427,0.355418633165829,"*",0.216958,"MCOLN3","GO:0005765//lysosomal membrane;GO:0031901//early endosome membrane;GO:0031902//late endosome membrane;GO:0016021//integral component of membrane;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0000421//autophagosome membrane","GO:0005262//calcium channel activity","GO:0070588//calcium ion transmembrane transport;GO:0007626//locomotory behavior;GO:0042491//inner ear auditory receptor cell differentiation","K04994//mucolipin 3","XP_011540041.2//PREDICTED: mucolipin-3 isoform X1 [Homo sapiens];XP_011540042.1//PREDICTED: mucolipin-3 isoform X3 [Homo sapiens]","1//3;10//2"]
[9973,1068,15.37,18.6,0.275185456304623,0.0943022780870035,"*",0.0436976,"CCS","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0004784//superoxide dismutase activity;GO:0015035//protein disulfide oxidoreductase activity;GO:0046872//metal ion binding;GO:0016532//superoxide dismutase copper chaperone activity;GO:0005507//copper ion binding;GO:0008270//zinc ion binding;GO:0045296//cadherin binding","GO:0006801//superoxide metabolic process;GO:0015680//intracellular copper ion transport;GO:0034599//cellular response to oxidative stress;GO:0051353//positive regulation of oxidoreductase activity;GO:0030001//metal ion transport","K04569//copper chaperone for superoxide dismutase","NP_005116.1//copper chaperone for superoxide dismutase [Homo sapiens]","1//3"]
[55317,1836,20.02,24.21,0.274161105162943,0.00696337839037232,"*",0.00231822,"AP5S1","NA","NA","NA","K19024//AP-5 complex subunit sigma-1","XP_011907569.1//PREDICTED: AP-5 complex subunit sigma-1 isoform X2 [Cercocebus atys]","1//3;2//1"]
[80097,954,88.87,107.46,0.274031349874134,{"v":2.52526435325924E-5,"d":"2.53E-05"},"*",{"v":5.26268e-06,"d":"5.26E-06"},"MZT2B","GO:0005654//nucleoplasm;GO:0005815//microtubule organizing center;GO:0008274//gamma-tubulin ring complex;GO:0005829//cytosol;GO:0005819//spindle;GO:0005813//centrosome","NA","NA","K16574//mitotic-spindle organizing protein 2A/2B","XP_001166562.2//PREDICTED: mitotic-spindle organizing protein 2B-like [Pan troglodytes];NP_001317213.1//mitotic-spindle organizing protein 2B isoform 3 [Homo sapiens];XP_009441596.1//PREDICTED: mitotic-spindle organizing protein 2B isoform X1 [Pan troglodytes]","4;1//3"]
[91689,1585,5.61,6.78,0.273284502527551,0.243056543839733,"*",0.1367136,"SMDT1","GO:0005759//mitochondrial matrix;GO:0005634//nucleus;GO:1990246//uniplex complex;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0031305//integral component of mitochondrial inner membrane","NA","GO:0006851//mitochondrial calcium ion transmembrane transport;GO:0051560//mitochondrial calcium ion homeostasis;GO:0036444//mitochondrial calcium uptake","NA","NP_201575.3//essential MCU regulator, mitochondrial precursor [Homo sapiens]",4]
[257144,3355,0.24,0.29,0.273018494406416,0.772196926937693,"*",0.67421,"GCSAM","GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0003779//actin binding;GO:0045159//myosin II binding;GO:0019901//protein kinase binding","GO:0050855//regulation of B cell receptor signaling pathway;GO:2000402//negative regulation of lymphocyte migration","NA","NP_001177188.1//germinal center-associated signaling and motility protein isoform 3 [Homo sapiens];NP_001177189.1//germinal center-associated signaling and motility protein isoform 4 [Homo sapiens];NP_689998.1//germinal center-associated signaling and motility protein isoform 1 [Homo sapiens]","4;1//3"]
[387707,1851,37.53,45.32,0.272103570933539,1.01236961304348E-4,"*",{"v":2.33224e-05,"d":"2.33E-05"},"CC2D2B","NA","NA","NA","K01510//apyrase [EC:3.6.1.5];K19352//coiled-coil and C2 domain-containing protein 2A","NP_001335937.1//protein CC2D2B isoform 3 [Homo sapiens];NP_001001732.2//protein CC2D2B isoform 2 [Homo sapiens];XP_011538093.1//PREDICTED: protein CC2D2B isoform X3 [Homo sapiens];NP_001123918.2//protein CC2D2B isoform 4 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[51372,580,114.9,138.62,0.270756625574845,3.41118009350394E-4,"*",{"v":8.6785e-05,"d":"8.68E-05"},"TMA7","NA","NA","NA","K06562//lysosomal-associated membrane protein 3","EDL06269.1//mCG52157, partial [Mus musculus]","1//3;5"]
[10300,2661,16.46,19.85,0.270174671608695,3.31475436476976E-3,"*",0.001031944,"KATNB1","GO:0016020//membrane;GO:0008352//katanin complex;GO:0030424//axon;GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005874//microtubule;GO:0015630//microtubule cytoskeleton;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0043025//neuronal cell body;GO:0030496//midbody;GO:0030426//growth cone;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0070840//dynein complex binding;GO:0008568//microtubule-severing ATPase activity;GO:0046982//protein heterodimerization activity;GO:0008017//microtubule binding","GO:0006605//protein targeting;GO:0031117//positive regulation of microtubule depolymerization;GO:0010976//positive regulation of neuron projection development;GO:0007079//mitotic chromosome movement towards spindle pole;GO:0051301//cell division;GO:0007026//negative regulation of microtubule depolymerization;GO:0051013//microtubule severing;GO:0007049//cell cycle;GO:0010942//positive regulation of cell death","K18643//katanin p80 WD40 repeat-containing subunit B1","NP_005877.2//katanin p80 WD40 repeat-containing subunit B1 [Homo sapiens]","2//1"]
[7627,2276,3.9,4.7,0.269186632815389,0.711700792362769,"*",0.597376,"ZNF75A","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein;K09229//KRAB and SCAN domains-containing zinc finger protein","XP_012503228.1//PREDICTED: zinc finger protein 75A isoform X2 [Propithecus coquereli];XP_012661173.1//PREDICTED: zinc finger protein 75A [Otolemur garnettii];XP_006054991.1//PREDICTED: uncharacterized protein LOC102394770 [Bubalus bubalis]","1//3;3//A2MP1"]
[6152,579,501.54,603.82,0.267753776601909,{"v":7.67492945679012e-15,"d":"7.67E-15"},"*",{"v":5.44846E-16,"d":"5.45E-16"},"RPL24","GO:0005840//ribosome;GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0022625//cytosolic large ribosomal subunit;GO:0005737//cytoplasm;GO:0022626//cytosolic ribosome","GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0045296//cadherin binding","GO:0031290//retinal ganglion cell axon guidance;GO:0060041//retina development in camera-type eye;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0000027//ribosomal large subunit assembly;GO:0006364//rRNA processing;GO:0006413//translational initiation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0007093//mitotic cell cycle checkpoint;GO:1902626//assembly of large subunit precursor of preribosome;GO:0010458//exit from mitosis;GO:0019083//viral transcription;GO:0006412//translation;GO:0021554//optic nerve development","K02896//large subunit ribosomal protein L24e","AAH02110.2//Rpl24 protein, partial [Mus musculus]","3//A2MP1"]
[56964,1980,0.54,0.65,0.267480310864986,0.796344158759253,"*",0.707158,"WDR93","NA","GO:0016651//oxidoreductase activity, acting on NAD(P)H","GO:0022900//electron transport chain","K17985//activating molecule in BECN1-regulated autophagy protein 1;K15696//RING finger protein 113B;K01064//wingless-type MMTV integration site family, member 9","NP_064597.1//WD repeat-containing protein 93 isoform 1 [Homo sapiens];NP_001271324.1//WD repeat-containing protein 93 isoform 2 [Homo sapiens];NP_001271325.1//WD repeat-containing protein 93 isoform 3 [Homo sapiens]","1//3"]
[5900,3683,8.62,10.37,0.266656119724128,0.0146092665903175,"*",5.27064E-3,"RALGDS","GO:0005634//nucleus;GO:0005903//brush border;GO:0005829//cytosol;GO:0005622//intracellular","GO:0005085//guanyl-nucleotide exchange factor activity;GO:0030695//GTPase regulator activity","GO:0007264//small GTPase mediated signal transduction;GO:0007265//Ras protein signal transduction","K08732//ral guanine nucleotide dissociation stimulator","NP_001258703.1//ral guanine nucleotide dissociation stimulator isoform 3 [Homo sapiens];NP_006257.1//ral guanine nucleotide dissociation stimulator isoform 1 [Homo sapiens];NP_001035827.1//ral guanine nucleotide dissociation stimulator isoform 2 [Homo sapiens];XP_016817454.1//PREDICTED: ral guanine nucleotide dissociation stimulator isoform X8 [Pan troglodytes];NP_001258705.1//ral guanine nucleotide dissociation stimulator isoform 5 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[10150,4755,4.6,5.53,0.265645619290332,0.084448464930412,"*",0.038365,"MBNL2","GO:0005654//nucleoplasm;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0046872//metal ion binding","GO:0043484//regulation of RNA splicing;GO:0006397//mRNA processing;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0008380//RNA splicing","K14943//muscleblind","NP_997187.1//muscleblind-like protein 2 isoform 3 [Homo sapiens];NP_659002.1//muscleblind-like protein 2 isoform 1 [Homo sapiens];NP_001292999.1//muscleblind-like protein 2 isoform 4 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[8751,2926,29.35,35.26,0.264671971322767,{"v":2.22938017259192e-05,"d":"2.23E-05"},"*",{"v":4.59302e-06,"d":"4.59E-06"},"ADAM15","GO:0070062//extracellular exosome;GO:0009986//cell surface;GO:0042995//cell projection;GO:0016021//integral component of membrane;GO:0001669//acrosomal vesicle;GO:0005886//plasma membrane;GO:0005912//adherens junction","GO:0046872//metal ion binding;GO:0008237//metallopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0005178//integrin binding;GO:0017124//SH3 domain binding","GO:1900121//negative regulation of receptor binding;GO:0030308//negative regulation of cell growth;GO:0060317//cardiac epithelial to mesenchymal transition;GO:0001525//angiogenesis;GO:0070528//protein kinase C signaling;GO:0030336//negative regulation of cell migration;GO:0042246//tissue regeneration;GO:0008584//male gonad development;GO:0007160//cell-matrix adhesion;GO:0022617//extracellular matrix disassembly;GO:0030198//extracellular matrix organization;GO:0001953//negative regulation of cell-matrix adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0045087//innate immune response;GO:0030574//collagen catabolic process","K06836//disintegrin and metalloproteinase domain-containing protein 15 [EC:3.4.24.-]","BAG59477.1//unnamed protein product [Homo sapiens];XP_007975128.1//PREDICTED: disintegrin and metalloproteinase domain-containing protein 15 isoform X12 [Chlorocebus sabaeus];XP_007975121.1//PREDICTED: disintegrin and metalloproteinase domain-containing protein 15 isoform X7 [Chlorocebus sabaeus];XP_007975117.1//PREDICTED: disintegrin and metalloproteinase domain-containing protein 15 isoform X3 [Chlorocebus sabaeus];AAS48591.1//ADAM15 isoform 3a [Homo sapiens];XP_007975130.1//PREDICTED: disintegrin and metalloproteinase domain-containing protein 15 isoform X14 [Chlorocebus sabaeus];XP_007975114.1//PREDICTED: disintegrin and metalloproteinase domain-containing protein 15 isoform X1 [Chlorocebus sabaeus];XP_007975125.1//PREDICTED: disintegrin and metalloproteinase domain-containing protein 15 isoform X10 [Chlorocebus sabaeus];NP_997078.1//disintegrin and metalloproteinase domain-containing protein 15 isoform 4 preproprotein [Homo sapiens]","4;1//3;2//1"]
[51011,1313,19.06,22.88,0.263538932868447,0.038954959017094,"*",0.01597802,"FAHD2A","NA","GO:0046872//metal ion binding;GO:0016787//hydrolase activity","GO:0008152//metabolic process","K01557//acylpyruvate hydrolase [EC:3.7.1.5]","NP_057128.2//fumarylacetoacetate hydrolase domain-containing protein 2A [Homo sapiens]","2//1"]
[1370,3025,0.15,0.18,0.263034405833794,0.695635420185143,"*",0.578622,"CPN2","GO:0070062//extracellular exosome;GO:0072562//blood microparticle;GO:0005576//extracellular region","GO:0004181//metallocarboxypeptidase activity;GO:0030234//enzyme regulator activity","GO:0030449//regulation of complement activation;GO:0050821//protein stabilization","K13023//carboxypeptidase N regulatory subunit","EAW78055.1//hCG2040284, partial [Homo sapiens]","1//3;3//A2MP1"]
[55697,3125,21.26,25.51,0.262921302071368,4.52881108903288E-4,"*",1.181392E-4,"VAC14","GO:0010008//endosome membrane;GO:0005783//endoplasmic reticulum;GO:0031901//early endosome membrane;GO:0070772//PAS complex;GO:0031902//late endosome membrane;GO:0000139//Golgi membrane","GO:0004872//receptor activity","GO:0007165//signal transduction;GO:0006661//phosphatidylinositol biosynthetic process;GO:0016032//viral process;GO:0043550//regulation of lipid kinase activity","K15305//vacuole morphology and inheritance protein 14","NP_060522.3//protein VAC14 homolog isoform 1 [Homo sapiens]","4;1//3"]
[27243,942,69.14,82.91,0.262025515977615,0.000523998655802937,"*",0.0001384952,"CHMP2A","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0000785//chromatin;GO:0005635//nuclear envelope;GO:0005622//intracellular;GO:0031902//late endosome membrane;GO:0030117//membrane coat;GO:0005829//cytosol;GO:0000815//ESCRT III complex","GO:0031210//phosphatidylcholine binding;GO:0019904//protein domain specific binding","GO:1903543//positive regulation of exosomal secretion;GO:0006997//nucleus organization;GO:1901673//regulation of mitotic spindle assembly;GO:0051260//protein homooligomerization;GO:0019058//viral life cycle;GO:0039702//viral budding via host ESCRT complex;GO:0050792//regulation of viral process;GO:0010324//membrane invagination;GO:1903723//negative regulation of centriole elongation;GO:1902188//positive regulation of viral release from host cell;GO:0000920//cell separation after cytokinesis;GO:0007080//mitotic metaphase plate congression;GO:0015031//protein transport;GO:0016197//endosomal transport;GO:0045184//establishment of protein localization;GO:0051291//protein heterooligomerization;GO:0007034//vacuolar transport;GO:0010824//regulation of centrosome duplication;GO:0051258//protein polymerization;GO:1904903//ESCRT III complex disassembly;GO:0036258//multivesicular body assembly;GO:0010458//exit from mitosis;GO:0060548//negative regulation of cell death;GO:0016236//macroautophagy;GO:0031468//nuclear envelope reassembly","K12191//charged multivesicular body protein 2A","XP_007175446.1//PREDICTED: charged multivesicular body protein 2a isoform X1 [Balaenoptera acutorostrata scammoni];XP_007955188.1//PREDICTED: charged multivesicular body protein 2a isoform X1 [Orycteropus afer afer]","3//A2MP1;2//1"]
[79767,2548,1.41,1.69,0.261328083883391,0.5187870507201,"*",0.36306,"ELMO3","NA","NA","GO:0016477//cell migration","K19241//engulfment and cell motility protein 3","EAW83097.1//engulfment and cell motility 3, isoform CRA_a [Homo sapiens]","3//A2MP1"]
[10598,1391,141.43,169.49,0.261111980360861,{"v":9.43514614532872e-09,"d":"9.44E-09"},"*",{"v":1.194898e-09,"d":"1.19E-09"},"AHSA1","GO:0070062//extracellular exosome;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol","GO:0001671//ATPase activator activity;GO:0051087//chaperone binding;GO:0045296//cadherin binding","GO:0006950//response to stress","K04131//muscarinic acetylcholine receptor M3","NP_036243.1//activator of 90 kDa heat shock protein ATPase homolog 1 isoform 1 [Homo sapiens]","1//3;2//1"]
[92822,4613,8.29,9.93,0.260421616032624,0.00931566814679569,"*",0.00319406,"ZNF276","GO:0005634//nucleus;GO:0000776//kinetochore;GO:0000777//condensed chromosome kinetochore","GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","NP_001106997.1//zinc finger protein 276 isoform a [Homo sapiens]","1//3;3//A2MP1"]
[7226,5774,3.76,4.5,0.2591923395394,0.284865294641314,"*",0.1650628,"TRPM2","GO:0005765//lysosomal membrane;GO:0042995//cell projection;GO:0101003//ficolin-1-rich granule membrane;GO:0005764//lysosome;GO:0043204//perikaryon;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane;GO:0005886//plasma membrane;GO:0070821//tertiary granule membrane;GO:0030659//cytoplasmic vesicle membrane","GO:0047631//ADP-ribose diphosphatase activity;GO:0005509//calcium ion binding;GO:0005272//sodium channel activity;GO:0099604//ligand-gated calcium channel activity;GO:0005262//calcium channel activity;GO:0005261//cation channel activity;GO:0015278//calcium-release channel activity","GO:0001659//temperature homeostasis;GO:0070588//calcium ion transmembrane transport;GO:0097553//calcium ion transmembrane import into cytosol;GO:0002407//dendritic cell chemotaxis;GO:0035584//calcium-mediated signaling using intracellular calcium source;GO:0071277//cellular response to calcium ion;GO:0071502//cellular response to temperature stimulus;GO:0098703//calcium ion import across plasma membrane;GO:0071415//cellular response to purine-containing compound;GO:0043312//neutrophil degranulation;GO:0071577//zinc II ion transmembrane transport;GO:0051489//regulation of filopodium assembly;GO:0070301//cellular response to hydrogen peroxide;GO:0006816//calcium ion transport;GO:0014074//response to purine-containing compound;GO:2000249//regulation of actin cytoskeleton reorganization;GO:0006979//response to oxidative stress;GO:0097028//dendritic cell differentiation;GO:0051209//release of sequestered calcium ion into cytosol","K04977//transient receptor potential cation channel subfamily M member 2 [EC:3.6.1.13]","NP_003298.1//transient receptor potential cation channel subfamily M member 2 isoform 1 [Homo sapiens];BAB64300.1//EREG1 [Homo sapiens];NP_001307279.1//transient receptor potential cation channel subfamily M member 2 isoform 2 [Homo sapiens];NP_001307280.1//transient receptor potential cation channel subfamily M member 2 isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[51524,1785,38.14,45.64,0.258993947975926,0.000201468183897436,"*",{"v":4.91878e-05,"d":"4.92E-05"},"TMEM138","GO:0005929//cilium;GO:0016021//integral component of membrane","NA","GO:0060271//cilium assembly","NA","XP_003419415.1//PREDICTED: transmembrane protein 138 isoform X1 [Loxodonta africana]","1//3;4"]
[4267,3377,122.74,146.8,0.258246479593065,{"v":5.96576602048998e-08,"d":"5.97E-08"},"*",{"v":8.38434E-9,"d":"8.38E-09"},"CD99","GO:0005887//integral component of plasma membrane;GO:0005925//focal adhesion;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm","NA","GO:0007155//cell adhesion;GO:0050776//regulation of immune response","K06520//CD99 antigen","NP_002405.1//CD99 antigen isoform a precursor [Homo sapiens];NP_001308299.1//CD99 antigen isoform f precursor [Homo sapiens];XP_007991428.1//PREDICTED: collagen alpha-1(I) chain-like [Chlorocebus sabaeus];NP_001116370.1//CD99 antigen isoform b precursor [Homo sapiens];NP_001308298.1//CD99 antigen isoform e precursor [Homo sapiens];NP_001308297.1//CD99 antigen isoform d precursor [Homo sapiens]","4;1//3;2//1"]
[5708,2823,80.42,96.15,0.257732521426899,{"v":4.16959551817238e-09,"d":"4.17E-09"},"*",{"v":5.02732E-10,"d":"5.03E-10"},"PSMD2","GO:0034774//secretory granule lumen;GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000502//proteasome complex;GO:0022624//proteasome accessory complex;GO:0005838//proteasome regulatory particle;GO:0034515//proteasome storage granule;GO:0005829//cytosol;GO:0005576//extracellular region;GO:1904813//ficolin-1-rich granule lumen;GO:0008540//proteasome regulatory particle, base subcomplex","GO:0030234//enzyme regulator activity","GO:0043687//post-translational protein modification;GO:0038061//NIK/NF-kappaB signaling;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0006521//regulation of cellular amino acid metabolic process;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0016579//protein deubiquitination;GO:0043312//neutrophil degranulation;GO:0043488//regulation of mRNA stability;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0000209//protein polyubiquitination;GO:0055085//transmembrane transport;GO:0000165//MAPK cascade;GO:0050852//T cell receptor signaling pathway;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0042176//regulation of protein catabolic process;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:1902036//regulation of hematopoietic stem cell differentiation","K03028//26S proteasome regulatory subunit N1","XP_015355414.1//PREDICTED: 26S proteasome non-ATPase regulatory subunit 2 [Marmota marmota marmota];NP_001265638.1//26S proteasome non-ATPase regulatory subunit 2 isoform 3 [Homo sapiens];XP_017393834.1//PREDICTED: 26S proteasome non-ATPase regulatory subunit 2 [Cebus capucinus imitator]","1//3;4"]
[4708,509,101.13,120.86,0.257125813994305,0.00370002152092467,"*",0.001162308,"NDUFB2","GO:0005747//mitochondrial respiratory chain complex I;GO:0005743//mitochondrial inner membrane","GO:0008137//NADH dehydrogenase (ubiquinone) activity","GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0055114//oxidation-reduction process","K03958//NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2","NP_004537.1//NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial precursor [Homo sapiens]","2//1"]
[130752,2527,0.72,0.86,0.256339753259786,0.688429737398129,"*",0.57112,"MDH1B","GO:0005737//cytoplasm","GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0016615//malate dehydrogenase activity;GO:0030060//L-malate dehydrogenase activity","GO:0006099//tricarboxylic acid cycle;GO:0006107//oxaloacetate metabolic process;GO:0005975//carbohydrate metabolic process;GO:0006734//NADH metabolic process;GO:0006108//malate metabolic process","K00025//malate dehydrogenase [EC:1.1.1.37]","NP_001269869.1//putative malate dehydrogenase 1B isoform b [Homo sapiens];NP_001034934.1//putative malate dehydrogenase 1B isoform a [Homo sapiens];NP_001317155.1//putative malate dehydrogenase 1B isoform f [Homo sapiens]","1//3;2//1"]
[11018,1739,14.09,16.82,0.255506093945508,0.0495556023700193,"*",0.0209434,"TMED1","GO:0043231//intracellular membrane-bounded organelle;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane","GO:0005102//receptor binding","GO:0006810//transport;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0015031//protein transport","K20348//p24 family protein gamma-1","NP_006849.1//transmembrane emp24 domain-containing protein 1 precursor [Homo sapiens]","3//A2MP1"]
[535,4188,24.21,28.9,0.255466413389104,{"v":1.1364724769821E-5,"d":"1.14E-05"},"*",{"v":2.22542E-6,"d":"2.23E-06"},"ATP6V0A1","GO:0005765//lysosomal membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0010008//endosome membrane;GO:0000220//vacuolar proton-transporting V-type ATPase, V0 domain;GO:0030667//secretory granule membrane;GO:0101003//ficolin-1-rich granule membrane;GO:0016607//nuclear speck;GO:0030670//phagocytic vesicle membrane;GO:0042470//melanosome;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0016471//vacuolar proton-transporting V-type ATPase complex;GO:0005886//plasma membrane","GO:0015078//hydrogen ion transmembrane transporter activity;GO:0051117//ATPase binding;GO:0046961//proton-transporting ATPase activity, rotational mechanism","GO:0016241//regulation of macroautophagy;GO:0008286//insulin receptor signaling pathway;GO:0034220//ion transmembrane transport;GO:0070072//vacuolar proton-transporting V-type ATPase complex assembly;GO:0090383//phagosome acidification;GO:0007035//vacuolar acidification;GO:0015986//ATP synthesis coupled proton transport;GO:0015991//ATP hydrolysis coupled proton transport;GO:1901998//toxin transport;GO:0033572//transferrin transport;GO:0043312//neutrophil degranulation","K02154//V-type H+-transporting ATPase subunit a","NP_001123492.1//V-type proton ATPase 116 kDa subunit a isoform 1 isoform a [Homo sapiens];NP_001123493.1//V-type proton ATPase 116 kDa subunit a isoform 1 isoform b [Homo sapiens];NP_005168.2//V-type proton ATPase 116 kDa subunit a isoform 1 isoform c [Homo sapiens]","1//3;3//A2MP1"]
[153830,3569,27.02,32.24,0.254824069202283,{"v":1.24906931087095e-05,"d":"1.25E-05"},"*",{"v":2.45998E-6,"d":"2.46E-06"},"RNF145","GO:0016021//integral component of membrane","GO:0061630//ubiquitin protein ligase activity;GO:0008270//zinc ion binding","GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0000209//protein polyubiquitination","K15703//E3 ubiquitin-protein ligase RNF139 [EC:2.3.2.27]","NP_001186311.1//RING finger protein 145 isoform 4 [Homo sapiens];NP_001186310.1//RING finger protein 145 isoform 3 [Homo sapiens];XP_021527876.1//LOW QUALITY PROTEIN: RING finger protein 145 [Aotus nancymaae];NP_653327.1//RING finger protein 145 isoform 2 [Homo sapiens]","1//3;2//1"]
[55957,1179,16.15,19.26,0.254073538262172,0.0953391044228695,"*",0.0442616,"LIN37","NA","NA","NA","K21774//protein lin-37","XP_004060585.1//PREDICTED: protein lin-37 homolog [Gorilla gorilla gorilla]","2//1"]
[55016,5389,0.26,0.31,0.253756592245783,0.733999604133314,"*",0.63144,"2019-03-01","GO:0005765//lysosomal membrane;GO:0031902//late endosome membrane;GO:0005764//lysosome;GO:0005768//endosome;GO:0032588//trans-Golgi network membrane;GO:0031901//early endosome membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0030659//cytoplasmic vesicle membrane","GO:0042287//MHC protein binding;GO:0061630//ubiquitin protein ligase activity;GO:0008270//zinc ion binding;GO:0004842//ubiquitin-protein transferase activity","GO:0006955//immune response;GO:0002495//antigen processing and presentation of peptide antigen via MHC class II;GO:0000209//protein polyubiquitination","K10656//E3 ubiquitin-protein ligase MARCH1/8 [EC:2.3.2.27]","XP_019296632.1//PREDICTED: E3 ubiquitin-protein ligase MARCH1 isoform X8 [Panthera pardus];XP_019296631.1//PREDICTED: E3 ubiquitin-protein ligase MARCH1 isoform X7 [Panthera pardus]","1//3;3//A2MP1"]
[4189,2538,2.77,3.3,0.252580048196627,0.355611510664479,"*",0.217098,"DNAJB9","GO:0070062//extracellular exosome;GO:0005788//endoplasmic reticulum lumen;GO:0005783//endoplasmic reticulum;GO:0005730//nucleolus;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005737//cytoplasm","GO:0051787//misfolded protein binding","GO:0036498//IRE1-mediated unfolded protein response;GO:0030433//ubiquitin-dependent ERAD pathway","K09515//DnaJ homolog subfamily B member 9","NP_036460.1//dnaJ homolog subfamily B member 9 precursor [Homo sapiens]","2//1"]
[51667,3149,15.97,19.02,0.252152933449331,0.00324367375201288,"*",1.0088E-3,"NUB1","GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005829//cytosol","NA","GO:0043687//post-translational protein modification;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0034612//response to tumor necrosis factor;GO:0034341//response to interferon-gamma;GO:0016567//protein ubiquitination;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process","NA","NP_057202.3//NEDD8 ultimate buster 1 isoform 2 [Homo sapiens];NP_001230280.1//NEDD8 ultimate buster 1 isoform 1 [Homo sapiens]","1//3;4"]
[7366,2264,0.21,0.25,0.251538766995964,0.858348326079542,"*",0.787688,"UGT2B15","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0015020//glucuronosyltransferase activity","GO:0008202//steroid metabolic process;GO:0008152//metabolic process;GO:0052695//cellular glucuronidation","K00699//glucuronosyltransferase [EC:2.4.1.17]","XP_003268480.1//PREDICTED: UDP-glucuronosyltransferase 2B15 isoform X1 [Nomascus leucogenys]","3//A2MP1"]
[123228,1569,1.21,1.44,0.251061764167718,0.695436021079575,"*",0.578282,"SENP8","GO:0005634//nucleus;GO:0005829//cytosol","GO:0004175//endopeptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0019784//NEDD8-specific protease activity","GO:0043687//post-translational protein modification;GO:0016579//protein deubiquitination;GO:0016926//protein desumoylation","K08597//sentrin-specific protease 8 [EC:3.4.22.68]","XP_011519517.1//PREDICTED: sentrin-specific protease 8 isoform X1 [Homo sapiens]","1//3;3//A2MP1"]
[90627,5723,0.58,0.69,0.250543461650597,0.562308590180968,"*",0.406542,"STARD13","GO:0005811//lipid droplet;GO:0005829//cytosol;GO:0031966//mitochondrial membrane","GO:0008289//lipid binding;GO:0005096//GTPase activator activity","GO:0090051//negative regulation of cell migration involved in sprouting angiogenesis;GO:0007165//signal transduction;GO:0097498//endothelial tube lumen extension;GO:0043542//endothelial cell migration;GO:0051056//regulation of small GTPase mediated signal transduction","K20632//deleted in liver cancer protein","NP_821074.1//stAR-related lipid transfer protein 13 isoform 1 [Homo sapiens];XP_007958277.1//PREDICTED: stAR-related lipid transfer protein 13 isoform X1 [Chlorocebus sabaeus];NP_821075.1//stAR-related lipid transfer protein 13 isoform 2 [Homo sapiens];XP_014202906.1//PREDICTED: stAR-related lipid transfer protein 13 isoform X4 [Pan paniscus];NP_001230395.1//stAR-related lipid transfer protein 13 isoform 5 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[10445,1815,43.94,52.24,0.249620027123154,0.000322825431152802,"*",{"v":8.18684e-05,"d":"8.19E-05"},"MCRS1","GO:0030425//dendrite;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005783//endoplasmic reticulum;GO:0031011//Ino80 complex;GO:0005737//cytoplasm;GO:0043204//perikaryon;GO:0071339//MLL1 complex;GO:0005730//nucleolus;GO:0000123//histone acetyltransferase complex;GO:0005844//polysome","GO:0046972//histone acetyltransferase activity (H4-K16 specific);GO:0002151//G-quadruplex RNA binding;GO:0008266//poly(U) RNA binding;GO:0043995//histone acetyltransferase activity (H4-K5 specific);GO:0034046//poly(G) binding;GO:0043996//histone acetyltransferase activity (H4-K8 specific);GO:0010521//telomerase inhibitor activity","GO:0043984//histone H4-K16 acetylation;GO:1904357//negative regulation of telomere maintenance via telomere lengthening;GO:0006281//DNA repair;GO:0006355//regulation of transcription, DNA-templated;GO:0043981//histone H4-K5 acetylation;GO:0006351//transcription, DNA-templated;GO:1904751//positive regulation of protein localization to nucleolus;GO:0051974//negative regulation of telomerase activity;GO:0006464//cellular protein modification process;GO:0043982//histone H4-K8 acetylation;GO:0016579//protein deubiquitination;GO:0006310//DNA recombination","K11674//microspherule protein 1","AAC68599.1//cell cycle-regulated factor p78 [Homo sapiens];ERE81194.1//Forkhead-associated (FHA) domain containing protein [Cricetulus griseus];NP_001012300.1//microspherule protein 1 isoform 2 [Homo sapiens]","4;1//3"]
[10227,1787,56.76,67.46,0.249157728957575,{"v":2.1606962435312e-05,"d":"2.16E-05"},"*",{"v":4.4434e-06,"d":"4.44E-06"},"MFSD10","GO:0031526//brush border membrane;GO:0016021//integral component of membrane;GO:0030659//cytoplasmic vesicle membrane","GO:0008493//tetracycline transmembrane transporter activity;GO:0008514//organic anion transmembrane transporter activity","GO:0006810//transport;GO:0043252//sodium-independent organic anion transport;GO:0006915//apoptotic process","K05202//glutamate receptor, ionotropic kainate 2;K19721//collagen, type V/XI/XXIV/XXVII, alpha;K13506//glycerol-3-phosphate O-acyltransferase 3/4 [EC:2.3.1.15];K03348//anaphase-promoting complex subunit 1;K08155//MFS transporter, DHA1 family, solute carrier family 18 (vesicular amine transporter), member 1/2","XP_002814566.2//PREDICTED: major facilitator superfamily domain-containing protein 10 [Pongo abelii];EAW82497.1//tetracycline transporter-like protein, isoform CRA_b [Homo sapiens]","1//3;4"]
[54939,805,100.15,119,0.248799152382598,0.000417291397388781,"*",1.080454E-4,"COMMD4","GO:0005634//nucleus;GO:0005737//cytoplasm","NA","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K20358//golgin subfamily A member 2","NP_001308777.1//COMM domain-containing protein 4 isoform 9 [Homo sapiens];XP_017403463.1//PREDICTED: COMM domain-containing protein 4 isoform X1 [Cebus capucinus imitator];XP_011520041.1//PREDICTED: COMM domain-containing protein 4 isoform X1 [Homo sapiens];XP_012362740.1//PREDICTED: COMM domain-containing protein 4 isoform X2 [Nomascus leucogenys];XP_017403464.1//PREDICTED: COMM domain-containing protein 4 isoform X2 [Cebus capucinus imitator]","1//3;4"]
[58500,6377,1.28,1.52,0.247927513443586,0.30467947526836,"*",0.1794622,"ZNF250","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_010628738.2//PREDICTED: zinc finger protein 250 [Fukomys damarensis]","4;3//A2MP1"]
[11092,2027,5.88,6.98,0.247410881373288,0.506956751124708,"*",0.352718,"SPACA9","GO:0005881//cytoplasmic microtubule;GO:0001669//acrosomal vesicle","GO:0048306//calcium-dependent protein binding","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K17985//activating molecule in BECN1-regulated autophagy protein 1","NP_001303826.1//sperm acrosome-associated protein 9 isoform a [Homo sapiens];NP_001303829.1//sperm acrosome-associated protein 9 isoform c [Homo sapiens];NP_061829.3//sperm acrosome-associated protein 9 isoform b [Homo sapiens]","4;1//3"]
[6303,1085,159.96,189.79,0.246692792765998,{"v":3.12334322041763e-08,"d":"3.12E-08"},"*",{"v":4.2136e-09,"d":"4.21E-09"},"SAT1","GO:0005829//cytosol;GO:0005622//intracellular","GO:0019809//spermidine binding;GO:0042802//identical protein binding;GO:0004145//diamine N-acetyltransferase activity","GO:0009447//putrescine catabolic process;GO:0001525//angiogenesis;GO:0032918//spermidine acetylation;GO:0042127//regulation of cell proliferation;GO:0046208//spermine catabolic process;GO:0006596//polyamine biosynthetic process","K00657//diamine N-acetyltransferase [EC:2.3.1.57]","AAP92609.1//Ab2-402 [Rattus norvegicus]","3//A2MP1"]
[10307,2154,4.14,4.91,0.246092256815368,0.355813915423902,"*",0.218068,"APBB3","NA","NA","NA","K04530//amyloid beta A4 precursor protein-binding family B member 2","XP_517974.4//PREDICTED: amyloid beta A4 precursor protein-binding family B member 3 isoform X4 [Pan troglodytes];XP_016809434.1//PREDICTED: amyloid beta A4 precursor protein-binding family B member 3 isoform X2 [Pan troglodytes];XP_001139279.3//PREDICTED: amyloid beta A4 precursor protein-binding family B member 3 isoform X3 [Pan troglodytes];XP_001139203.3//PREDICTED: amyloid beta A4 precursor protein-binding family B member 3 isoform X1 [Pan troglodytes]","3//A2MP1;2//1"]
[23647,3754,19.89,23.58,0.245520442146018,1.018998575E-3,"*",0.000285784,"ARFIP2","GO:0001726//ruffle;GO:0032588//trans-Golgi network membrane;GO:0005938//cell cortex;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0019904//protein domain specific binding;GO:0048365//Rac GTPase binding;GO:0070273//phosphatidylinositol-4-phosphate binding;GO:0042802//identical protein binding;GO:0030742//GTP-dependent protein binding;GO:0005525//GTP binding;GO:0045296//cadherin binding","GO:0030032//lamellipodium assembly;GO:0031529//ruffle organization;GO:0034315//regulation of Arp2/3 complex-mediated actin nucleation;GO:0006928//movement of cell or subcellular component;GO:0030036//actin cytoskeleton organization;GO:0007264//small GTPase mediated signal transduction","K20314//arfaptin","XP_004413367.1//PREDICTED: arfaptin-2 isoform X1 [Odobenus rosmarus divergens];XP_010335315.1//PREDICTED: arfaptin-2 isoform X1 [Saimiri boliviensis boliviensis];NP_001229783.1//arfaptin-2 isoform 1 [Homo sapiens];NP_001229785.1//arfaptin-2 isoform 4 [Homo sapiens]","1//3;3//A2MP1"]
[4117,3882,1.46,1.73,0.244803668756707,0.364256415526503,"*",0.224998,"MAK","GO:0072686//mitotic spindle;GO:0005929//cilium;GO:0005634//nucleus;GO:0001917//photoreceptor inner segment;GO:0005813//centrosome;GO:0001750//photoreceptor outer segment;GO:0005737//cytoplasm;GO:0030496//midbody","GO:0046872//metal ion binding;GO:0003713//transcription coactivator activity;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0004672//protein kinase activity","GO:0010468//regulation of gene expression;GO:0030154//cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006468//protein phosphorylation;GO:0006351//transcription, DNA-templated;GO:0035556//intracellular signal transduction;GO:0007283//spermatogenesis;GO:0045494//photoreceptor cell maintenance;GO:0046777//protein autophosphorylation;GO:0060271//cilium assembly;GO:0042073//intraciliary transport;GO:0007275//multicellular organism development","K08829//male germ cell-associated kinase [EC:2.7.11.22]","NP_005897.1//serine/threonine-protein kinase MAK isoform 1 [Homo sapiens];NP_001229886.1//serine/threonine-protein kinase MAK isoform 3 [Homo sapiens];NP_001229314.1//serine/threonine-protein kinase MAK isoform 2 [Homo sapiens]","1//3;2//1;5"]
[1716,1009,74.49,88.21,0.243895455141176,1.26658406491228E-3,"*",0.000361564,"DGUOK","GO:0005759//mitochondrial matrix;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005739//mitochondrion","GO:0004138//deoxyguanosine kinase activity;GO:0005524//ATP binding;GO:0019206//nucleoside kinase activity","GO:0046122//purine deoxyribonucleoside metabolic process;GO:0010977//negative regulation of neuron projection development;GO:0006468//protein phosphorylation;GO:0008617//guanosine metabolic process;GO:0046070//dGTP metabolic process;GO:0043101//purine-containing compound salvage","K00904//deoxyguanosine kinase [EC:2.7.1.113]","XP_003268725.1//PREDICTED: deoxyguanosine kinase, mitochondrial isoform X1 [Nomascus leucogenys];AAC50624.1//deoxyguanosine kinase [Homo sapiens];NP_550438.1//deoxyguanosine kinase, mitochondrial isoform a precursor [Homo sapiens];NP_550440.1//deoxyguanosine kinase, mitochondrial isoform b precursor [Homo sapiens];NP_001305788.1//deoxyguanosine kinase, mitochondrial isoform c precursor [Homo sapiens];XP_011530949.1//PREDICTED: deoxyguanosine kinase, mitochondrial isoform X1 [Homo sapiens]","1//3;2//1"]
[51659,1196,49.09,58.1,0.243108996925843,0.00248175106666667,"*",0.000750398,"GINS2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031298//replication fork protection complex;GO:0000811//GINS complex","NA","GO:0000727//double-strand break repair via break-induced replication;GO:0006260//DNA replication;GO:1902975//mitotic DNA replication initiation;GO:0006271//DNA strand elongation involved in DNA replication;GO:0032508//DNA duplex unwinding","K10733//GINS complex subunit 2","NP_057179.1//DNA replication complex GINS protein PSF2 [Homo sapiens]","2//1"]
[51367,801,27.29,32.28,0.24226818400364,0.0918375130081301,"*",0.042429,"POP5","GO:0000172//ribonuclease MRP complex;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0030681//multimeric ribonuclease P complex;GO:0005655//nucleolar ribonuclease P complex","GO:0004526//ribonuclease P activity","GO:0001682//tRNA 5'-leader removal;GO:0009249//protein lipoylation;GO:0008033//tRNA processing","K03537//ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]","NP_937845.1//ribonuclease P/MRP protein subunit POP5 isoform c [Homo sapiens];XP_017365737.1//PREDICTED: ribonuclease P/MRP protein subunit POP5 isoform X2 [Cebus capucinus imitator]","1//3;3//A2MP1"]
[107282092,1334,25.88,30.6,0.241694035587507,0.0485545116058178,"*",0.0204808,"BOLA2-SMG1P6","NA","GO:0016301//kinase activity","NA","K08873//serine/threonine-protein kinase SMG1 [EC:2.7.11.1]","NP_001307554.1//BOLA2-SMG1P6 protein isoform d [Homo sapiens];NP_001307551.1//BOLA2-SMG1P6 protein isoform a [Homo sapiens];NP_001307552.1//BOLA2-SMG1P6 protein isoform b [Homo sapiens];NP_001307553.1//BOLA2-SMG1P6 protein isoform c [Homo sapiens]","1//3"]
[7016,2463,42.04,49.69,0.241192872587931,{"v":6.00766148031496e-05,"d":"6.01E-05"},"*",{"v":1.337376e-05,"d":"1.34E-05"},"TESK1","GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0004713//protein tyrosine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0046872//metal ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0004871//signal transducer activity","GO:0035556//intracellular signal transduction;GO:0007283//spermatogenesis","K08841//testis-specific kinase 1 [EC:2.7.12.1]","NP_001305159.1//dual specificity testis-specific protein kinase 1 isoform 2 [Homo sapiens];NP_006276.2//dual specificity testis-specific protein kinase 1 isoform 1 [Homo sapiens]","1//3;2//1"]
[23203,2158,38.47,45.45,0.240546464784855,2.88133214855434E-4,"*",{"v":7.2367e-05,"d":"7.24E-05"},"PMPCA","GO:0005759//mitochondrial matrix;GO:0005615//extracellular space;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0046872//metal ion binding;GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding","GO:0006627//protein processing involved in protein targeting to mitochondrion;GO:0006851//mitochondrial calcium ion transmembrane transport;GO:0006508//proteolysis","K01412//mitochondrial-processing peptidase subunit alpha [EC:3.4.24.64]","BAA09472.2//KIAA0123, partial [Homo sapiens];NP_001269873.1//mitochondrial-processing peptidase subunit alpha isoform 2 [Homo sapiens];NP_001269875.1//mitochondrial-processing peptidase subunit alpha isoform 3 [Homo sapiens]","1//3;2//1"]
[2197,579,297.91,351.77,0.239755899087457,{"v":1.70562705018979E-7,"d":"1.71E-07"},"*",{"v":2.53164e-08,"d":"2.53E-08"},"FAU","NA","NA","NA","K02983//small subunit ribosomal protein S30e","XP_012352516.1//PREDICTED: putative ubiquitin-like protein FUBI-like protein ENSP00000310146 [Nomascus leucogenys]",4]
[3455,2178,7.95,9.38,0.238633062343659,0.0150888443491789,"*",0.00546444,"IFNAR2","GO:0005615//extracellular space;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005622//intracellular;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0019962//type I interferon binding;GO:0004905//type I interferon receptor activity;GO:0019901//protein kinase binding","GO:0035456//response to interferon-beta;GO:0060337//type I interferon signaling pathway;GO:0007259//JAK-STAT cascade;GO:0051607//defense response to virus;GO:0007166//cell surface receptor signaling pathway;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0035455//response to interferon-alpha;GO:0008283//cell proliferation;GO:0060338//regulation of type I interferon-mediated signaling pathway;GO:0009615//response to virus","K05131//interferon receptor 2","XP_009452600.1//PREDICTED: interferon alpha/beta receptor 2 isoform X3 [Pan troglodytes];XP_009452503.1//PREDICTED: interferon alpha/beta receptor 2 isoform X1 [Pan troglodytes];XP_018873344.1//PREDICTED: interferon alpha/beta receptor 2 isoform X2 [Gorilla gorilla gorilla]","4;1//3;2//1"]
[84926,2949,25.39,29.94,0.237813826410911,5.91497397701149E-4,"*",1.578536E-4,"SPRYD3","NA","NA","NA","K04967//transient receptor potential cation channel subfamily C member 4","XP_008001558.1//PREDICTED: SPRY domain-containing protein 3 [Chlorocebus sabaeus]","2//1"]
[2023,1802,1559,1838.14,0.237625724126524,{"v":8.51291026987952e-113,"d":"8.51E-113"},"*",{"v":4.42326e-115,"d":"4.42E-115"},"ENO1","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0099738//cell cortex region;GO:0005737//cytoplasm;GO:0009986//cell surface;GO:0031430//M band;GO:0005829//cytosol;GO:0000015//phosphopyruvate hydratase complex;GO:0005886//plasma membrane","GO:0000287//magnesium ion binding;GO:0003723//RNA binding;GO:0004634//phosphopyruvate hydratase activity;GO:0042803//protein homodimerization activity;GO:0001227//transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0045296//cadherin binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0051020//GTPase binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0030308//negative regulation of cell growth;GO:0061621//canonical glycolysis;GO:2001171//positive regulation of ATP biosynthetic process;GO:0006094//gluconeogenesis;GO:0006096//glycolytic process;GO:0006351//transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045933//positive regulation of muscle contraction;GO:1903298//negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway;GO:0010756//positive regulation of plasminogen activation;GO:0009615//response to virus","K01689//enolase [EC:4.2.1.11]","CAH56247.1//hypothetical protein, partial [Homo sapiens];XP_012353756.1//PREDICTED: alpha-enolase isoform X1 [Nomascus leucogenys];NP_001340275.1//alpha-enolase isoform 3 [Homo sapiens]","4;3//A2MP1;2//1"]
[29924,2484,212.92,250.83,0.236398437620636,{"v":4.74777792134831E-21,"d":"4.75E-21"},"*",{"v":2.1162e-22,"d":"2.12E-22"},"EPN1","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005905//clathrin-coated pit;GO:0005886//plasma membrane","GO:0008289//lipid binding","GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0007565//female pregnancy;GO:0006897//endocytosis;GO:0007219//Notch signaling pathway;GO:0001701//in utero embryonic development;GO:0048568//embryonic organ development;GO:0061024//membrane organization","K12471//epsin","NP_001123543.1//epsin-1 isoform a [Homo sapiens];XP_011852369.1//PREDICTED: epsin-1 isoform X1 [Mandrillus leucophaeus]","1//3;3//A2MP1"]
[6100,1184,15.11,17.8,0.236373580688931,0.141780237618809,"*",0.07097,"RP9","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005785//signal recognition particle receptor complex","GO:0003723//RNA binding;GO:0046872//metal ion binding","GO:0050890//cognition;GO:0008380//RNA splicing","K19604//retinitis pigmentosa 9 protein","EAL24464.1//similar to RP9 protein [Homo sapiens]","1//3"]
[1936,1343,319.96,376.6,0.235141442991609,{"v":1.71757021073559E-16,"d":"1.72E-16"},"*",{"v":1.08168e-17,"d":"1.08E-17"},"EEF1D","GO:0005634//nucleus;GO:0005829//cytosol;GO:0001650//fibrillar center;GO:0005853//eukaryotic translation elongation factor 1 complex;GO:0005737//cytoplasm","GO:0008135//translation factor activity, RNA binding;GO:0003677//DNA binding;GO:0031072//heat shock protein binding;GO:0003746//translation elongation factor activity;GO:0004871//signal transducer activity;GO:0033613//activating transcription factor binding;GO:0045296//cadherin binding","GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0010941//regulation of cell death;GO:0006355//regulation of transcription, DNA-templated;GO:0071479//cellular response to ionizing radiation;GO:0009299//mRNA transcription;GO:0006414//translational elongation;GO:0006351//transcription, DNA-templated","K15410//elongation factor 1-delta","BAG36963.1//unnamed protein product [Homo sapiens];XP_011732883.1//PREDICTED: LOW QUALITY PROTEIN: elongation factor 1-delta-like [Macaca nemestrina];XP_016868661.1//PREDICTED: elongation factor 1-delta isoform X6 [Homo sapiens];NP_001182132.1//elongation factor 1-delta isoform 5 [Homo sapiens];NP_115754.3//elongation factor 1-delta isoform 1 [Homo sapiens];XP_016868660.1//PREDICTED: elongation factor 1-delta isoform X5 [Homo sapiens]","1//3;3//A2MP1;2//1;5"]
[56521,1013,7.83,9.21,0.234188848800295,0.37867418258427,"*",0.236298,"DNAJC12","GO:0005737//cytoplasm","NA","NA","K09532//DnaJ homolog subfamily C member 12","NP_068572.1//dnaJ homolog subfamily C member 12 isoform a [Homo sapiens];NP_957714.1//dnaJ homolog subfamily C member 12 isoform b [Homo sapiens]","1//3;2//1"]
[728294,2653,6.15,7.23,0.233409236724516,0.192905568342951,"*",0.1025392,"D2HGDH","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0016614//oxidoreductase activity, acting on CH-OH group of donors;GO:0004458//D-lactate dehydrogenase (cytochrome) activity;GO:0050660//flavin adenine dinucleotide binding;GO:0051990//(R)-2-hydroxyglutarate dehydrogenase activity;GO:0071949//FAD binding","GO:0044267//cellular protein metabolic process;GO:0010042//response to manganese ion;GO:0032025//response to cobalt ion;GO:0022904//respiratory electron transport chain;GO:0019516//lactate oxidation;GO:0006103//2-oxoglutarate metabolic process;GO:0010043//response to zinc ion","K18204//D-2-hydroxyglutarate dehydrogenase [EC:1.1.99.39]","NP_689996.4//D-2-hydroxyglutarate dehydrogenase, mitochondrial isoform 1 precursor [Homo sapiens]","4;1//3"]
[341,588,72.37,85.02,0.232410487369321,0.0202821909926716,"*",0.00762328,"APOC1","GO:0070062//extracellular exosome;GO:0005783//endoplasmic reticulum;GO:0042627//chylomicron;GO:0034364//high-density lipoprotein particle;GO:0005576//extracellular region;GO:0034361//very-low-density lipoprotein particle","GO:0004859//phospholipase inhibitor activity;GO:0060228//phosphatidylcholine-sterol O-acyltransferase activator activity;GO:0031210//phosphatidylcholine binding;GO:0055102//lipase inhibitor activity;GO:0005504//fatty acid binding","GO:0045833//negative regulation of lipid metabolic process;GO:0010916//negative regulation of very-low-density lipoprotein particle clearance;GO:0051005//negative regulation of lipoprotein lipase activity;GO:0008203//cholesterol metabolic process;GO:0033344//cholesterol efflux;GO:0034379//very-low-density lipoprotein particle assembly;GO:0050995//negative regulation of lipid catabolic process;GO:0034382//chylomicron remnant clearance;GO:0032374//regulation of cholesterol transport;GO:0042157//lipoprotein metabolic process;GO:0010900//negative regulation of phosphatidylcholine catabolic process;GO:0032375//negative regulation of cholesterol transport;GO:0006641//triglyceride metabolic process;GO:0048261//negative regulation of receptor-mediated endocytosis;GO:0034369//plasma lipoprotein particle remodeling;GO:0045717//negative regulation of fatty acid biosynthetic process;GO:0033700//phospholipid efflux;GO:0034375//high-density lipoprotein particle remodeling;GO:0034447//very-low-density lipoprotein particle clearance;GO:0010873//positive regulation of cholesterol esterification;GO:0006629//lipid metabolic process","K22286//apolipoprotein C-I","NP_001636.1//apolipoprotein C-I precursor [Homo sapiens]","1//3;4"]
[388135,5663,0.92,1.08,0.231325546106456,0.507744692037787,"*",0.353298,"C15orf59","NA","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K01064//wingless-type MMTV integration site family, member 9","NP_001034703.1//UPF0583 protein C15orf59 isoform 1 [Homo sapiens];XP_012584239.1//PREDICTED: UPF0583 protein C15orf59 homolog isoform X1 [Condylura cristata]","1//3;2//1"]
[10555,1542,66.37,77.91,0.231277240506743,{"v":9.62937999454297e-05,"d":"9.63E-05"},"*",{"v":2.20932e-05,"d":"2.21E-05"},"AGPAT2","GO:0005783//endoplasmic reticulum;GO:0035579//specific granule membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane","GO:0016746//transferase activity, transferring acyl groups;GO:0003841//1-acylglycerol-3-phosphate O-acyltransferase activity","GO:0042493//response to drug;GO:0008152//metabolic process;GO:0001819//positive regulation of cytokine production;GO:0016024//CDP-diacylglycerol biosynthetic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0008654//phospholipid biosynthetic process;GO:0001961//positive regulation of cytokine-mediated signaling pathway;GO:0008544//epidermis development;GO:0006644//phospholipid metabolic process;GO:0043312//neutrophil degranulation","K13509//lysophosphatidate acyltransferase [EC:2.3.1.51]","NP_001012745.1//1-acyl-sn-glycerol-3-phosphate acyltransferase beta isoform b precursor [Homo sapiens];NP_006403.2//1-acyl-sn-glycerol-3-phosphate acyltransferase beta isoform a precursor [Homo sapiens]","1//3;3//A2MP1"]
[90952,1869,6.71,7.87,0.230050869307303,0.245061162966252,"*",0.138194,"ESAM","GO:0070062//extracellular exosome;GO:0016021//integral component of membrane;GO:0005923//bicellular tight junction;GO:0005886//plasma membrane;GO:0005912//adherens junction","NA","GO:0050900//leukocyte migration;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules","K06787//endothelial cell adhesion molecule","NP_620411.2//endothelial cell-selective adhesion molecule precursor [Homo sapiens]","2//1"]
[3763,2790,0.29,0.34,0.229481846122767,0.77214156438199,"*",0.67421,"KCNJ6","GO:0005887//integral component of plasma membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex","GO:0005242//inward rectifier potassium channel activity;GO:0015467//G-protein activated inward rectifier potassium channel activity","GO:0006813//potassium ion transport;GO:0010107//potassium ion import","K05000//potassium inwardly-rectifying channel subfamily J member 6","XP_007966108.1//PREDICTED: G protein-activated inward rectifier potassium channel 2 isoform X1 [Chlorocebus sabaeus]",4]
[25873,465,335.19,392.88,0.229109619078799,{"v":1.63920690749543e-06,"d":"1.64E-06"},"*",{"v":2.80658e-07,"d":"2.81E-07"},"RPL36","GO:0005840//ribosome;GO:0016020//membrane;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0022625//cytosolic large ribosomal subunit;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome","GO:0006413//translational initiation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0019083//viral transcription;GO:0006412//translation;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0002181//cytoplasmic translation;GO:0006364//rRNA processing","K02920//large subunit ribosomal protein L36e;K01530//phospholipid-translocating ATPase [EC:3.6.3.1]","XP_014996838.1//PREDICTED: probable phospholipid-transporting ATPase VB [Macaca mulatta];XP_021526953.1//rabankyrin-5 [Aotus nancymaae]","3//A2MP1;2//1"]
[29882,2733,18.7,21.91,0.228551214215223,0.00836329216011806,"*",0.0028382,"ANAPC2","GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005680//anaphase-promoting complex","GO:0031625//ubiquitin protein ligase binding","GO:0050775//positive regulation of dendrite morphogenesis;GO:0070979//protein K11-linked ubiquitination;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0045773//positive regulation of axon extension;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0051301//cell division;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0031915//positive regulation of synaptic plasticity;GO:0090129//positive regulation of synapse maturation","K03349//anaphase-promoting complex subunit 2","NP_037498.1//anaphase-promoting complex subunit 2 [Homo sapiens]","3//A2MP1"]
[10960,1853,102.93,120.54,0.227848438175637,{"v":7.06016992592593e-08,"d":"7.06E-08"},"*",{"v":1.002408E-8,"d":"1.00E-08"},"LMAN2","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0005794//Golgi apparatus;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005789//endoplasmic reticulum membrane;GO:0000139//Golgi membrane","GO:0046872//metal ion binding;GO:0030246//carbohydrate binding;GO:0031072//heat shock protein binding;GO:0005537//mannose binding","GO:0050766//positive regulation of phagocytosis;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0015031//protein transport","K10082//lectin, mannose-binding 2","NP_006807.1//vesicular integral-membrane protein VIP36 precursor [Homo sapiens]","2//1"]
[8986,3118,42.42,49.67,0.227630125906683,{"v":2.5742615904048E-5,"d":"2.57E-05"},"*",{"v":5.37446e-06,"d":"5.37E-06"},"RPS6KA4","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005737//cytoplasm","GO:0000287//magnesium ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004711//ribosomal protein S6 kinase activity","GO:0006355//regulation of transcription, DNA-templated;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction;GO:0070498//interleukin-1-mediated signaling pathway;GO:0033129//positive regulation of histone phosphorylation;GO:0006954//inflammatory response;GO:0032793//positive regulation of CREB transcription factor activity;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0043987//histone H3-S10 phosphorylation;GO:0001818//negative regulation of cytokine production;GO:0035066//positive regulation of histone acetylation;GO:0043988//histone H3-S28 phosphorylation;GO:0016572//histone phosphorylation","K16510//ribosomal protein S6 kinase alpha-4 [EC:2.7.11.1]","NP_001006945.1//ribosomal protein S6 kinase alpha-4 isoform b [Homo sapiens];NP_003933.1//ribosomal protein S6 kinase alpha-4 isoform a [Homo sapiens];NP_001287731.1//ribosomal protein S6 kinase alpha-4 isoform c [Homo sapiens]","1//3;2//1"]
[57452,3148,1.06,1.24,0.226275855823676,0.896469456644295,"*",0.836196,"GALNT16","GO:0070062//extracellular exosome;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0004653//polypeptide N-acetylgalactosaminyltransferase activity;GO:0046872//metal ion binding;GO:0030246//carbohydrate binding;GO:0016757//transferase activity, transferring glycosyl groups","GO:0006486//protein glycosylation;GO:0018242//protein O-linked glycosylation via serine;GO:0018243//protein O-linked glycosylation via threonine","K00710//polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41]","EDL02668.1//mCG7620, isoform CRA_b [Mus musculus]","1//3;2//1"]
[10715,2564,3.72,4.35,0.225712779628059,0.373342451729686,"*",0.23241,"CERS1","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0000139//Golgi membrane;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005789//endoplasmic reticulum membrane","GO:0008083//growth factor activity;GO:0005125//cytokine activity;GO:0050291//sphingosine N-acyltransferase activity;GO:0005160//transforming growth factor beta receptor binding","GO:0035690//cellular response to drug;GO:0030148//sphingolipid biosynthetic process;GO:0043408//regulation of MAPK cascade;GO:0030509//BMP signaling pathway;GO:0036146//cellular response to mycotoxin;GO:0051974//negative regulation of telomerase activity;GO:0060395//SMAD protein signal transduction;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0072721//cellular response to dithiothreitol;GO:0042981//regulation of apoptotic process;GO:0048468//cell development;GO:0071492//cellular response to UV-A;GO:0046513//ceramide biosynthetic process","K05495//growth differentiation factor 1/3;K04710//ceramide synthetase [EC:2.3.1.24]","NP_001483.3//embryonic growth/differentiation factor 1 precursor [Homo sapiens];NP_067090.1//ceramide synthase 1 isoform 1 [Homo sapiens]","4;1//3;2//1"]
[64763,3167,25.95,30.34,0.22548654700179,0.000671720764226135,"*",1.814916E-4,"ZNF574","NA","GO:0003676//nucleic acid binding","NA","K09228//KRAB domain-containing zinc finger protein","XP_021526078.1//zinc finger protein 574 isoform X2 [Aotus nancymaae]","1//3;5"]
[57060,2047,15.26,17.83,0.224551740790464,0.12847453101775,"*",0.0629826,"PCBP4","NA","NA","NA","K21444//poly(rC)-binding protein 3/4","XP_005265389.1//PREDICTED: poly(rC)-binding protein 4 isoform X3 [Homo sapiens];XP_012352205.1//PREDICTED: poly(rC)-binding protein 4 isoform X1 [Nomascus leucogenys];XP_005265387.1//PREDICTED: poly(rC)-binding protein 4 isoform X1 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[112812,864,16.62,19.41,0.223879735943319,0.232588390669508,"*",0.1298354,"FDX1L","GO:0005759//mitochondrial matrix","GO:0009055//electron transfer activity;GO:0046872//metal ion binding;GO:0051537//2 iron, 2 sulfur cluster binding","GO:0006700//C21-steroid hormone biosynthetic process;GO:0016125//sterol metabolic process;GO:0055114//oxidation-reduction process;GO:0044281//small molecule metabolic process","K22071//ferredoxin-2, mitochondrial","NP_001026904.2//ferredoxin-2, mitochondrial precursor [Homo sapiens]","3//A2MP1"]
[11015,1699,8.72,10.18,0.223337521298769,0.213436576066597,"*",0.1155636,"KDELR3","GO:0005783//endoplasmic reticulum;GO:0030133//transport vesicle;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0000139//Golgi membrane","GO:0046923//ER retention sequence binding","GO:0036498//IRE1-mediated unfolded protein response;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0015031//protein transport;GO:0006621//protein retention in ER lumen","K10949//ER lumen protein retaining receptor","NP_006846.1//ER lumen protein-retaining receptor 3 isoform a [Homo sapiens];NP_057839.1//ER lumen protein-retaining receptor 3 isoform b [Homo sapiens]","3//A2MP1;2//1"]
[25988,2323,5.51,6.43,0.22276641875679,0.186458836251483,"*",0.0984004,"HINFP","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0030054//cell junction;GO:0015030//Cajal body","GO:0042393//histone binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0003713//transcription coactivator activity;GO:0003682//chromatin binding;GO:0019899//enzyme binding;GO:0003700//DNA binding transcription factor activity","GO:0045892//negative regulation of transcription, DNA-templated;GO:0045184//establishment of protein localization;GO:0010468//regulation of gene expression;GO:0006281//DNA repair;GO:0006355//regulation of transcription, DNA-templated;GO:0000077//DNA damage checkpoint;GO:0006351//transcription, DNA-templated;GO:0010629//negative regulation of gene expression;GO:0001701//in utero embryonic development;GO:0010628//positive regulation of gene expression;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045445//myoblast differentiation;GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0000082//G1/S transition of mitotic cell cycle","K09228//KRAB domain-containing zinc finger protein","XP_003820055.1//PREDICTED: histone H4 transcription factor isoform X2 [Pan paniscus];XP_003253310.1//PREDICTED: histone H4 transcription factor isoform X1 [Nomascus leucogenys];XP_008971677.1//PREDICTED: histone H4 transcription factor isoform X1 [Pan paniscus];XP_011541046.1//PREDICTED: histone H4 transcription factor isoform X1 [Homo sapiens];NP_001230188.1//histone H4 transcription factor isoform 2 [Homo sapiens];XP_009422583.1//PREDICTED: histone H4 transcription factor isoform X1 [Pan troglodytes];NP_001338886.1//histone H4 transcription factor isoform 3 [Homo sapiens];XP_016872988.1//PREDICTED: histone H4 transcription factor isoform X3 [Homo sapiens]","4;1//3;2//1"]
[6167,1586,235.31,274.55,0.222506279016386,{"v":7.62521896563012e-14,"d":"7.63E-14"},"*",{"v":5.83324e-15,"d":"5.83E-15"},"RPL37","GO:0005840//ribosome;GO:0005829//cytosol;GO:0022625//cytosolic large ribosomal subunit","GO:0003723//RNA binding;GO:0046872//metal ion binding;GO:0019838//growth factor binding;GO:0003735//structural constituent of ribosome;GO:0019843//rRNA binding","GO:0006413//translational initiation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0019083//viral transcription;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006412//translation;GO:0006364//rRNA processing","K02922//large subunit ribosomal protein L37e","AFA34383.1//ribosomal protein L37 [Ostrea edulis]",4]
[643802,1286,0.06,0.07,0.222392421336448,1.00623301488771,"*",0.998548,"LOC643802","NA","NA","NA","K14559//U3 small nucleolar RNA-associated protein MPP10","XP_007991369.1//PREDICTED: LOW QUALITY PROTEIN: U3 small nucleolar ribonucleoprotein protein MPP10 [Chlorocebus sabaeus]","1//3"]
[79661,1724,2.77,3.23,0.221648188644736,0.526009041662949,"*",0.369102,"NEIL1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005815//microtubule organizing center;GO:0005694//chromosome;GO:0005737//cytoplasm","GO:0003906//DNA-(apurinic or apyrimidinic site) lyase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0003684//damaged DNA binding;GO:0008022//protein C-terminus binding;GO:0140078//class I DNA-(apurinic or apyrimidinic site) lyase activity;GO:0019104//DNA N-glycosylase activity;GO:0008270//zinc ion binding;GO:0140080//class III/IV DNA-(apurinic or apyrimidinic site) lyase activity","GO:0006979//response to oxidative stress;GO:0006284//base-excision repair;GO:0045008//depyrimidination;GO:0006289//nucleotide-excision repair;GO:0032074//negative regulation of nuclease activity","K10567//endonuclease VIII-like 1 [EC:3.2.2.- 4.2.99.18]","NP_001243481.1//endonuclease 8-like 1 isoform 1 [Homo sapiens];NP_001339448.1//endonuclease 8-like 1 isoform 4 [Homo sapiens];NP_001339449.1//endonuclease 8-like 1 isoform 5 [Homo sapiens];XP_011520303.2//PREDICTED: endonuclease 8-like 1 isoform X2 [Homo sapiens]","1//3;3//A2MP1"]
[9404,1926,1.75,2.04,0.221214230139167,0.557136944077805,"*",0.401652,"LPXN","GO:0016020//membrane;GO:0005634//nucleus;GO:0042995//cell projection;GO:0005925//focal adhesion;GO:0016607//nuclear speck;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0002102//podosome;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0046872//metal ion binding;GO:0003712//transcription cofactor activity","GO:0033628//regulation of cell adhesion mediated by integrin;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0006355//regulation of transcription, DNA-templated;GO:0007162//negative regulation of cell adhesion;GO:0050859//negative regulation of B cell receptor signaling pathway;GO:0006351//transcription, DNA-templated;GO:0006461//protein complex assembly","K05760//paxillin","NP_001137467.1//leupaxin isoform 1 [Homo sapiens];NP_001294880.1//leupaxin isoform 3 [Homo sapiens];NP_004802.1//leupaxin isoform 2 [Homo sapiens]","1//3;2//1"]
[25855,1430,52.75,61.46,0.220476673111052,0.00201326309301835,"*",0.000597526,"BRMS1","NA","NA","GO:0009987//cellular process","K19196//breast cancer metastasis-suppressor 1 and related proteins","XP_011842310.1//PREDICTED: breast cancer metastasis-suppressor 1 isoform X2 [Mandrillus leucophaeus];NP_001020128.1//breast cancer metastasis-suppressor 1 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[284339,1779,3.89,4.53,0.219740895060043,0.447185460489445,"*",0.29971,"TMEM145","GO:0016021//integral component of membrane","NA","GO:0007186//G-protein coupled receptor signaling pathway;GO:0019236//response to pheromone","K07188//hormone-sensitive lipase [EC:3.1.1.79]","NP_775904.2//transmembrane protein 145 precursor [Homo sapiens]","2//1"]
[4055,2222,135.86,158.16,0.219264016880844,{"v":2.14237767180174E-11,"d":"2.14E-11"},"*",{"v":2.00236E-12,"d":"2.00E-12"},"LTBR","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0042802//identical protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0005031//tumor necrosis factor-activated receptor activity","GO:0046330//positive regulation of JNK cascade;GO:0007165//signal transduction;GO:0071260//cellular response to mechanical stimulus;GO:0042127//regulation of cell proliferation;GO:0032496//response to lipopolysaccharide;GO:0016032//viral process;GO:0006954//inflammatory response;GO:0006915//apoptotic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0007275//multicellular organism development;GO:0006955//immune response;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0043011//myeloid dendritic cell differentiation","K03159//lymphotoxin beta receptor TNFR superfamily member 3","NP_001257916.1//tumor necrosis factor receptor superfamily member 3 isoform 2 [Homo sapiens];NP_002333.1//tumor necrosis factor receptor superfamily member 3 isoform 1 precursor [Homo sapiens]","1//3;2//1"]
[5524,2573,113.06,131.59,0.218961255519063,{"v":2.08520131397459e-10,"d":"2.09E-10"},"*",{"v":2.15778e-11,"d":"2.16E-11"},"PTPA","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0034704//calcium channel complex;GO:0000159//protein phosphatase type 2A complex;GO:0005737//cytoplasm","GO:0008160//protein tyrosine phosphatase activator activity;GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005524//ATP binding;GO:0046982//protein heterodimerization activity;GO:0005102//receptor binding;GO:0019888//protein phosphatase regulator activity;GO:0051721//protein phosphatase 2A binding;GO:0042803//protein homodimerization activity;GO:0016887//ATPase activity","GO:0030472//mitotic spindle organization in nucleus;GO:0043065//positive regulation of apoptotic process;GO:0035308//negative regulation of protein dephosphorylation;GO:0043666//regulation of phosphoprotein phosphatase activity;GO:0032515//negative regulation of phosphoprotein phosphatase activity;GO:0035307//positive regulation of protein dephosphorylation;GO:0032516//positive regulation of phosphoprotein phosphatase activity","K17605//serine/threonine-protein phosphatase 2A activator","EAW87881.1//protein phosphatase 2A, regulatory subunit B' (PR 53), isoform CRA_f [Homo sapiens];NP_066954.2//serine/threonine-protein phosphatase 2A activator isoform b [Homo sapiens];EAW87885.1//protein phosphatase 2A, regulatory subunit B' (PR 53), isoform CRA_j [Homo sapiens];XP_001163459.2//PREDICTED: serine/threonine-protein phosphatase 2A activator isoform X3 [Pan troglodytes];EAW87877.1//protein phosphatase 2A, regulatory subunit B' (PR 53), isoform CRA_b [Homo sapiens];XP_011517140.1//PREDICTED: serine/threonine-protein phosphatase 2A activator isoform X5 [Homo sapiens]","4;1//3;2//1"]
[27341,5455,21.72,25.27,0.218401561140414,{"v":5.8959196108291e-05,"d":"5.90E-05"},"*",{"v":1.30881e-05,"d":"1.31E-05"},"RRP7A","GO:0005654//nucleoplasm;GO:0032545//CURI complex;GO:0005737//cytoplasm;GO:0034456//UTP-C complex","GO:0003723//RNA binding","GO:0000028//ribosomal small subunit assembly;GO:0001825//blastocyst formation;GO:0006364//rRNA processing","K14545//ribosomal RNA-processing protein 7","XP_016794803.1//PREDICTED: ribosomal RNA-processing protein 7 homolog A [Pan troglodytes]",4]
[51147,1439,6.08,7.07,0.217638891365813,0.398804501112509,"*",0.258072,"ING4","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000123//histone acetyltransferase complex","GO:0046872//metal ion binding;GO:0003713//transcription coactivator activity;GO:0035064//methylated histone binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0045926//negative regulation of growth;GO:0006260//DNA replication;GO:0043981//histone H4-K5 acetylation;GO:0016573//histone acetylation;GO:0006473//protein acetylation;GO:0007050//cell cycle arrest;GO:0006915//apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0043966//histone H3 acetylation;GO:0043982//histone H4-K8 acetylation;GO:0043983//histone H4-K12 acetylation;GO:0008285//negative regulation of cell proliferation;GO:0006978//DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator","K11346//inhibitor of growth protein 4","NP_001121055.1//inhibitor of growth protein 4 isoform 3 [Homo sapiens];NP_001121056.1//inhibitor of growth protein 4 isoform 4 [Homo sapiens];NP_001121058.1//inhibitor of growth protein 4 isoform 6 [Homo sapiens];NP_057246.2//inhibitor of growth protein 4 isoform 1 [Homo sapiens];NP_001121054.1//inhibitor of growth protein 4 isoform 9 [Homo sapiens];NP_001121057.1//inhibitor of growth protein 4 isoform 5 [Homo sapiens]","1//3;3//A2MP1"]
[6139,753,547.52,636.46,0.217158182077484,{"v":1.79305928140556e-12,"d":"1.79E-12"},"*",{"v":1.533316E-13,"d":"1.53E-13"},"RPL17","NA","NA","NA","K02880//large subunit ribosomal protein L17e","XP_005983921.1//PREDICTED: 60S ribosomal protein L17-like [Pantholops hodgsonii];XP_017173407.1//PREDICTED: 60S ribosomal protein L17 isoform X1 [Mus musculus];XP_011929989.1//PREDICTED: 60S ribosomal protein L17 isoform X1 [Cercocebus atys]","4;1//3;2//1"]
[1647,1313,8.38,9.74,0.21697152838299,0.524732067845028,"*",0.367976,"GADD45A","GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0016607//nuclear speck;GO:0005737//cytoplasm","GO:0047485//protein N-terminus binding;GO:0046982//protein heterodimerization activity;GO:0019900//kinase binding;GO:0042803//protein homodimerization activity;GO:0001047//core promoter binding","GO:0046330//positive regulation of JNK cascade;GO:0007098//centrosome cycle;GO:0071260//cellular response to mechanical stimulus;GO:0006950//response to stress;GO:0007050//cell cycle arrest;GO:0000185//activation of MAPKKK activity;GO:0043065//positive regulation of apoptotic process;GO:0071850//mitotic cell cycle arrest;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0006281//DNA repair;GO:0006915//apoptotic process;GO:1900745//positive regulation of p38MAPK cascade;GO:0006469//negative regulation of protein kinase activity;GO:0042770//signal transduction in response to DNA damage;GO:0071479//cellular response to ionizing radiation;GO:0051726//regulation of cell cycle;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity","K04402//growth arrest and DNA-damage-inducible protein","NP_001186670.1//growth arrest and DNA damage-inducible protein GADD45 alpha isoform 2 [Homo sapiens];NP_001915.1//growth arrest and DNA damage-inducible protein GADD45 alpha isoform 1 [Homo sapiens];NP_001186671.1//growth arrest and DNA damage-inducible protein GADD45 alpha isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[56901,1275,1.98,2.3,0.216133430864766,0.659332779427522,"*",0.539304,"NDUFA4L2","NA","NA","NA","K03948//NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4","XP_011536875.1//PREDICTED: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 isoform X1 [Homo sapiens]","3//A2MP1"]
[8859,1622,3.78,4.39,0.215834705314285,0.497568611287254,"*",0.34385,"STK19","GO:0005634//nucleus;GO:0016607//nuclear speck","GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding","GO:0006468//protein phosphorylation","K08880//serine/threonine kinase 19 [EC:2.7.11.1]","XP_009449215.2//PREDICTED: serine/threonine-protein kinase 19 isoform X2 [Pan troglodytes]","1//3"]
[6277,683,774.05,898.51,0.215107799638313,{"v":2.59428928262712e-17,"d":"2.59E-17"},"*",{"v":1.533122E-18,"d":"1.53E-18"},"S100A6","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0001726//ruffle;GO:0005829//cytosol;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0005576//extracellular region","GO:0005523//tropomyosin binding;GO:0044548//S100 protein binding;GO:0005509//calcium ion binding;GO:0008270//zinc ion binding;GO:0015075//ion transmembrane transporter activity;GO:0048306//calcium-dependent protein binding;GO:0042803//protein homodimerization activity","GO:0007165//signal transduction;GO:0048146//positive regulation of fibroblast proliferation;GO:0007409//axonogenesis","K21128//protein S100-A9;K17274//calpactin-1 light chain","XP_008853760.1//PREDICTED: protein S100-A6 [Nannospalax galili]","3//A2MP1"]
[2297,2272,5.73,6.65,0.214819201631647,0.276820594681428,"*",0.1596562,"FOXD1","GO:0005634//nucleus","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:0043565//sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0008301//DNA binding, bending","GO:0090184//positive regulation of kidney development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0009653//anatomical structure morphogenesis;GO:0030154//cell differentiation;GO:0030513//positive regulation of BMP signaling pathway;GO:0010628//positive regulation of gene expression;GO:0072210//metanephric nephron development;GO:0072267//metanephric capsule specification;GO:0072076//nephrogenic mesenchyme development;GO:0032275//luteinizing hormone secretion;GO:0060678//dichotomous subdivision of terminal units involved in ureteric bud branching;GO:0007411//axon guidance;GO:0072213//metanephric capsule development","K09397//forkhead box protein D","NP_004463.1//forkhead box protein D1 [Homo sapiens]","2//1"]
[4350,1079,54.35,63.04,0.213987499541705,0.0129258033947045,"*",4.61474E-3,"MPG","GO:0005654//nucleoplasm;GO:0042645//mitochondrial nucleoid","GO:0003905//alkylbase DNA N-glycosylase activity;GO:0003677//DNA binding;GO:0052821//DNA-7-methyladenine glycosylase activity;GO:0008725//DNA-3-methyladenine glycosylase activity;GO:0003684//damaged DNA binding;GO:0019104//DNA N-glycosylase activity;GO:0043916//DNA-7-methylguanine glycosylase activity;GO:0052822//DNA-3-methylguanine glycosylase activity","GO:0006307//DNA dealkylation involved in DNA repair;GO:0045007//depurination;GO:0006284//base-excision repair","K03652//DNA-3-methyladenine glycosylase [EC:3.2.2.21]","NP_001015052.1//DNA-3-methyladenine glycosylase isoform b [Homo sapiens];NP_002425.2//DNA-3-methyladenine glycosylase isoform a [Homo sapiens];XP_016784459.1//PREDICTED: DNA-3-methyladenine glycosylase isoform X1 [Pan troglodytes]","3//A2MP1;2//1"]
[10067,1586,106.78,123.79,0.213253321397439,{"v":3.49264173587522e-06,"d":"3.49E-06"},"*",{"v":6.30792e-07,"d":"6.31E-07"},"SCAMP3","GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0016021//integral component of membrane","GO:0031625//ubiquitin protein ligase binding","GO:0006892//post-Golgi vesicle-mediated transport;GO:0015031//protein transport","K19995//secretory carrier-associated membrane protein","NP_005689.2//secretory carrier-associated membrane protein 3 isoform 1 [Homo sapiens];NP_443069.1//secretory carrier-associated membrane protein 3 isoform 2 [Homo sapiens]","3//A2MP1;2//1"]
[8448,2091,11.74,13.6,0.21217424302765,0.10325152173913,"*",0.048465,"DOC2A","NA","NA","NA","K19916//double C2-like domain-containing protein alpha","XP_004057516.2//PREDICTED: double C2-like domain-containing protein alpha isoform X1 [Gorilla gorilla gorilla]","1//3;2//1"]
[23327,8367,3.48,4.03,0.211692532679239,0.0773073928651059,"*",0.0347288,"NEDD4L","GO:0070062//extracellular exosome;GO:0005654//nucleoplasm;GO:0005622//intracellular;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0005771//multivesicular body;GO:0005886//plasma membrane","GO:0061630//ubiquitin protein ligase activity;GO:0015459//potassium channel regulator activity;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0019871//sodium channel inhibitor activity;GO:0044325//ion channel binding;GO:0019870//potassium channel inhibitor activity;GO:0017080//sodium channel regulator activity","GO:0070936//protein K48-linked ubiquitination;GO:0034220//ion transmembrane transport;GO:0016567//protein ubiquitination;GO:1901380//negative regulation of potassium ion transmembrane transport;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0045807//positive regulation of endocytosis;GO:0019058//viral life cycle;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:1901017//negative regulation of potassium ion transmembrane transporter activity;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0003254//regulation of membrane depolarization;GO:1902306//negative regulation of sodium ion transmembrane transport;GO:0006883//cellular sodium ion homeostasis;GO:2000650//negative regulation of sodium ion transmembrane transporter activity;GO:0006814//sodium ion transport;GO:0010038//response to metal ion;GO:0042391//regulation of membrane potential;GO:0000209//protein polyubiquitination;GO:0086005//ventricular cardiac muscle cell action potential;GO:2000009//negative regulation of protein localization to cell surface;GO:0006513//protein monoubiquitination;GO:0030104//water homeostasis;GO:0034765//regulation of ion transmembrane transport;GO:0007588//excretion;GO:2001288//positive regulation of caveolin-mediated endocytosis;GO:1901016//regulation of potassium ion transmembrane transporter activity;GO:1903861//positive regulation of dendrite extension;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0042176//regulation of protein catabolic process;GO:0060306//regulation of membrane repolarization;GO:0045732//positive regulation of protein catabolic process","K13305//E3 ubiquitin-protein ligase NEDD4-like [EC:2.3.2.26]","NP_001138441.1//E3 ubiquitin-protein ligase NEDD4-like isoform 5 [Homo sapiens];NP_056092.2//E3 ubiquitin-protein ligase NEDD4-like isoform 3 [Homo sapiens];NP_001138439.1//E3 ubiquitin-protein ligase NEDD4-like isoform 1 [Homo sapiens];NP_001138440.1//E3 ubiquitin-protein ligase NEDD4-like isoform 4 [Homo sapiens];XP_011524189.1//PREDICTED: E3 ubiquitin-protein ligase NEDD4-like isoform X10 [Homo sapiens];NP_001230889.1//E3 ubiquitin-protein ligase NEDD4-like isoform 7 [Homo sapiens];EHH29321.1//hypothetical protein EGK_09715, partial [Macaca mulatta]","1//3;2//1;5"]
[171024,5617,0.95,1.1,0.211504105193712,0.890241861303558,"*",0.828548,"SYNPO2","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005925//focal adhesion;GO:0001725//stress fiber;GO:0030018//Z disc;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0099023//tethering complex","GO:0003779//actin binding;GO:0071889//14-3-3 protein binding;GO:0051393//alpha-actinin binding;GO:0031005//filamin binding;GO:0051371//muscle alpha-actinin binding","GO:2000298//regulation of Rho-dependent protein serine/threonine kinase activity;GO:0030335//positive regulation of cell migration;GO:0032233//positive regulation of actin filament bundle assembly;GO:0000045//autophagosome assembly","K12581//CCR4-NOT transcription complex subunit 7/8;K06245//laminin, beta 4;K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K02927//large subunit ribosomal protein L40e;K21112//synaptopodin;K12025//tripartite motif-containing protein 52","AAI50630.1//Synaptopodin 2 [Homo sapiens];NP_001122406.1//synaptopodin-2 isoform c [Homo sapiens];NP_001273683.1//synaptopodin-2 isoform d [Homo sapiens];NP_597734.2//synaptopodin-2 isoform a [Homo sapiens];NP_001122405.1//synaptopodin-2 isoform b [Homo sapiens]","1//3;2//1"]
[55831,2660,22.18,25.67,0.210823930413709,0.00878094653196179,"*",0.00299258,"EMC3","GO:0072546//ER membrane protein complex;GO:0016021//integral component of membrane","NA","GO:0034975//protein folding in endoplasmic reticulum","K12581//CCR4-NOT transcription complex subunit 7/8;K01064//wingless-type MMTV integration site family, member 9;K12025//tripartite motif-containing protein 52","EDK99483.1//mCG132973, isoform CRA_a, partial [Mus musculus]","3//A2MP1"]
[51763,3133,16.58,19.18,0.21015871352238,0.0202530522138931,"*",0.00761106,"INPP5K","GO:0016020//membrane;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0032587//ruffle membrane;GO:0005802//trans-Golgi network;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0043005//neuron projection;GO:0001726//ruffle;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0005000//vasopressin receptor activity;GO:0004445//inositol-polyphosphate 5-phosphatase activity;GO:0034485//phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity;GO:0046030//inositol trisphosphate phosphatase activity;GO:0042577//lipid phosphatase activity;GO:0052659//inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity;GO:0016787//hydrolase activity;GO:0004439//phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity;GO:0034595//phosphatidylinositol phosphate 5-phosphatase activity;GO:0034594//phosphatidylinositol trisphosphate phosphatase activity;GO:0016312//inositol bisphosphate phosphatase activity;GO:0052658//inositol-1,4,5-trisphosphate 5-phosphatase activity","GO:0043407//negative regulation of MAP kinase activity;GO:0006661//phosphatidylinositol biosynthetic process;GO:0071356//cellular response to tumor necrosis factor;GO:0042593//glucose homeostasis;GO:0097178//ruffle assembly;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0043922//negative regulation by host of viral transcription;GO:0051898//negative regulation of protein kinase B signaling;GO:0045892//negative regulation of transcription, DNA-templated;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0030036//actin cytoskeleton organization;GO:0001933//negative regulation of protein phosphorylation;GO:0046855//inositol phosphate dephosphorylation;GO:0045719//negative regulation of glycogen biosynthetic process;GO:0010801//negative regulation of peptidyl-threonine phosphorylation;GO:0035305//negative regulation of dephosphorylation;GO:0071320//cellular response to cAMP;GO:0051926//negative regulation of calcium ion transport;GO:0045869//negative regulation of single stranded viral RNA replication via double stranded DNA intermediate;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051497//negative regulation of stress fiber assembly;GO:0016311//dephosphorylation;GO:0007186//G-protein coupled receptor signaling pathway;GO:0072659//protein localization to plasma membrane;GO:0090315//negative regulation of protein targeting to membrane;GO:2000466//negative regulation of glycogen (starch) synthase activity;GO:0001701//in utero embryonic development;GO:0032870//cellular response to hormone stimulus;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0032869//cellular response to insulin stimulus;GO:0006469//negative regulation of protein kinase activity;GO:2001153//positive regulation of renal water transport;GO:0005979//regulation of glycogen biosynthetic process;GO:0010829//negative regulation of glucose transport;GO:0035810//positive regulation of urine volume;GO:0046856//phosphatidylinositol dephosphorylation","K01106//inositol-1,4,5-trisphosphate 5-phosphatase [EC:3.1.3.56]","NP_057616.2//inositol polyphosphate 5-phosphatase K isoform 1 [Homo sapiens];EAW90617.1//skeletal muscle and kidney enriched inositol phosphatase, isoform CRA_d [Homo sapiens]","1//3;3//A2MP1;2//1"]
[7051,2777,0.32,0.37,0.20945336562895,0.780496302939711,"*",0.68644,"TGM1","GO:0031224//intrinsic component of membrane;GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0001533//cornified envelope;GO:0005886//plasma membrane","GO:0046872//metal ion binding;GO:0003810//protein-glutamine gamma-glutamyltransferase activity","GO:0018149//peptide cross-linking;GO:0043163//cell envelope organization;GO:0006464//cellular protein modification process;GO:0030216//keratinocyte differentiation;GO:0010838//positive regulation of keratinocyte proliferation;GO:0045787//positive regulation of cell cycle;GO:0070268//cornification","K05619//transglutaminase 1 [EC:2.3.2.13]","NP_000350.1//protein-glutamine gamma-glutamyltransferase K [Homo sapiens]","2//1"]
[11199,1447,10.08,11.65,0.208834316041726,0.262499539054291,"*",0.1501312,"ANXA10","GO:0005739//mitochondrion","GO:0005544//calcium-dependent phospholipid binding;GO:0005509//calcium ion binding","NA","K17097//annexin A10","NP_009124.2//annexin A10 [Homo sapiens]",4]
[114787,4208,7.55,8.72,0.207851490564485,0.0730601378071038,"*",0.0325784,"GPRIN1","GO:0030426//growth cone;GO:0005886//plasma membrane","GO:0051219//phosphoprotein binding","GO:0031175//neuron projection development","K22020//mucin-19;K03626//nascent polypeptide-associated complex subunit alpha","NP_443131.2//G protein-regulated inducer of neurite outgrowth 1 [Homo sapiens]","2//1"]
[410,4187,10.47,12.08,0.20635901239427,0.0392570611987189,"*",0.01611422,"ARSA","GO:0070062//extracellular exosome;GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0031232//extrinsic component of external side of plasma membrane;GO:0001669//acrosomal vesicle;GO:0005764//lysosome;GO:0005768//endosome;GO:0035578//azurophil granule lumen;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0043202//lysosomal lumen","GO:0008484//sulfuric ester hydrolase activity;GO:0004098//cerebroside-sulfatase activity;GO:0005509//calcium ion binding;GO:0004065//arylsulfatase activity","GO:0043687//post-translational protein modification;GO:0008152//metabolic process;GO:0009268//response to pH;GO:0043627//response to estrogen;GO:0007417//central nervous system development;GO:0045471//response to ethanol;GO:0007339//binding of sperm to zona pellucida;GO:0006687//glycosphingolipid metabolic process;GO:0051597//response to methylmercury;GO:0007584//response to nutrient;GO:0043312//neutrophil degranulation;GO:0006914//autophagy","K01134//arylsulfatase A [EC:3.1.6.8]","NP_000478.3//arylsulfatase A isoform a precursor [Homo sapiens]","2//1;5"]
[120227,1633,5.74,6.62,0.20578048013153,0.391976538605292,"*",0.249482,"CYP2R1","GO:0031090//organelle membrane;GO:0005789//endoplasmic reticulum membrane","GO:0008395//steroid hydroxylase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0020037//heme binding;GO:0005506//iron ion binding;GO:0004497//monooxygenase activity;GO:0030343//vitamin D3 25-hydroxylase activity","GO:0006766//vitamin metabolic process;GO:0010212//response to ionizing radiation;GO:0010164//response to cesium ion;GO:0042359//vitamin D metabolic process","K07419//vitamin D 25-hydroxylase [EC:1.14.14.24]","NP_078790.2//vitamin D 25-hydroxylase [Homo sapiens]",4]
[10005,1188,10.25,11.82,0.205606125784724,0.323805108345534,"*",0.193829,"ACOT8","GO:0005782//peroxisomal matrix;GO:0005739//mitochondrion","GO:0033882//choloyl-CoA hydrolase activity;GO:0047617//acyl-CoA hydrolase activity;GO:0016289//CoA hydrolase activity;GO:0052815//medium-chain acyl-CoA hydrolase activity;GO:0052689//carboxylic ester hydrolase activity;GO:0016290//palmitoyl-CoA hydrolase activity;GO:0005102//receptor binding;GO:0003986//acetyl-CoA hydrolase activity","GO:0045225//negative regulation of CD4 biosynthetic process;GO:0033540//fatty acid beta-oxidation using acyl-CoA oxidase;GO:0043649//dicarboxylic acid catabolic process;GO:0016032//viral process;GO:0036109//alpha-linolenic acid metabolic process;GO:0009062//fatty acid catabolic process;GO:0006637//acyl-CoA metabolic process;GO:0006699//bile acid biosynthetic process;GO:0016559//peroxisome fission","K11992//acyl-CoA thioesterase 8 [EC:3.1.2.27]","NP_005460.2//acyl-coenzyme A thioesterase 8 [Homo sapiens]","3//A2MP1"]
[2950,986,504.43,581.3,0.204628828850972,{"v":3.65707744072398e-15,"d":"3.66E-15"},"*",{"v":2.52978e-16,"d":"2.53E-16"},"GSTP1","GO:0097057//TRAF2-GSTP1 complex;GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0005622//intracellular;GO:0031982//vesicle;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005576//extracellular region;GO:1904813//ficolin-1-rich granule lumen;GO:0005739//mitochondrion;GO:0005886//plasma membrane","GO:0004364//glutathione transferase activity;GO:0035730//S-nitrosoglutathione binding;GO:0008432//JUN kinase binding;GO:0004602//glutathione peroxidase activity;GO:0070026//nitric oxide binding;GO:0019901//protein kinase binding;GO:0008144//drug binding;GO:0043295//glutathione binding;GO:0019207//kinase regulator activity;GO:0035731//dinitrosyl-iron complex binding","GO:0032930//positive regulation of superoxide anion generation;GO:0031100//animal organ regeneration;GO:0032872//regulation of stress-activated MAPK cascade;GO:0010804//negative regulation of tumor necrosis factor-mediated signaling pathway;GO:0043407//negative regulation of MAP kinase activity;GO:0071222//cellular response to lipopolysaccharide;GO:0032691//negative regulation of interleukin-1 beta production;GO:0071672//negative regulation of smooth muscle cell chemotaxis;GO:0045471//response to ethanol;GO:0032355//response to estradiol;GO:0014003//oligodendrocyte development;GO:0002674//negative regulation of acute inflammatory response;GO:0033591//response to L-ascorbic acid;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0035732//nitric oxide storage;GO:0006805//xenobiotic metabolic process;GO:0070664//negative regulation of leukocyte proliferation;GO:0043066//negative regulation of apoptotic process;GO:0048147//negative regulation of fibroblast proliferation;GO:0032873//negative regulation of stress-activated MAPK cascade;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0035726//common myeloid progenitor cell proliferation;GO:0006749//glutathione metabolic process;GO:0034599//cellular response to oxidative stress;GO:0071460//cellular response to cell-matrix adhesion;GO:0043200//response to amino acid;GO:0071385//cellular response to glucocorticoid stimulus;GO:0032720//negative regulation of tumor necrosis factor production;GO:0051771//negative regulation of nitric-oxide synthase biosynthetic process;GO:0009636//response to toxic substance;GO:0000302//response to reactive oxygen species;GO:0043651//linoleic acid metabolic process;GO:0043508//negative regulation of JUN kinase activity;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:0043312//neutrophil degranulation;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:1901687//glutathione derivative biosynthetic process;GO:1904706//negative regulation of vascular smooth muscle cell proliferation;GO:0009890//negative regulation of biosynthetic process;GO:0071638//negative regulation of monocyte chemotactic protein-1 production;GO:0007417//central nervous system development;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0032869//cellular response to insulin stimulus;GO:0043409//negative regulation of MAPK cascade;GO:0006469//negative regulation of protein kinase activity","K00799//glutathione S-transferase [EC:2.5.1.18]","NP_000843.1//glutathione S-transferase P [Homo sapiens]","3//A2MP1"]
[6222,549,634.23,730.88,0.204628435187177,{"v":1.86174249367397E-10,"d":"1.86E-10"},"*",{"v":1.916054E-11,"d":"1.92E-11"},"RPS18","GO:0016020//membrane;GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005925//focal adhesion;GO:0022627//cytosolic small ribosomal subunit","GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome","GO:0006412//translation","K02964//small subunit ribosomal protein S18e","XP_003271942.1//PREDICTED: 40S ribosomal protein S18 [Nomascus leucogenys]","2//1"]
[10446,3207,4.61,5.31,0.203945110374815,0.271556956970291,"*",0.1562124,"LRRN2","GO:0005615//extracellular space;GO:0016021//integral component of membrane;GO:0005578//proteinaceous extracellular matrix","GO:0004872//receptor activity","GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007409//axonogenesis","K19511//peroxidase [EC:1.11.1.7];K12655//OTU domain-containing protein 5 [EC:3.4.19.12];K16351//netrin-G2 ligand","NP_006329.2//leucine-rich repeat neuronal protein 2 precursor [Homo sapiens]","1//3;2//1"]
[79149,2029,2.78,3.2,0.202987022163855,0.600625109754029,"*",0.443306,"ZSCAN5A","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein;K09229//KRAB and SCAN domains-containing zinc finger protein;K09230//SCAN domain-containing zinc finger protein","XP_010385348.1//PREDICTED: zinc finger and SCAN domain-containing protein 5A isoform X3 [Rhinopithecus roxellana];XP_010385345.1//PREDICTED: zinc finger and SCAN domain-containing protein 5A isoform X1 [Rhinopithecus roxellana];XP_010385347.1//PREDICTED: zinc finger and SCAN domain-containing protein 5A isoform X2 [Rhinopithecus roxellana];XP_011750249.1//PREDICTED: zinc finger and SCAN domain-containing protein 5A isoform X3 [Macaca nemestrina]","1//3;2//1"]
[85455,5048,0.53,0.61,0.202816882999687,0.673781283242259,"*",0.555762,"DISP2","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","NA","GO:0007224//smoothened signaling pathway","K10649//tripartite motif-containing protein 9/67;K21245//transcription factor SPT20 homolog;K04490//transcription factor 7-like 1","EAW92408.1//dispatched homolog 2 (Drosophila), isoform CRA_b, partial [Homo sapiens]","2//1"]
[342850,4748,0.2,0.23,0.20163386116965,0.788021286078099,"*",0.69735,"ANKRD62","NA","NA","NA","K17299//POTE ankyrin domain family protein","NP_001264262.1//ankyrin repeat domain-containing protein 62 [Homo sapiens]","1//3"]
[100271849,1472,8.43,9.69,0.200964034472999,0.331354527931681,"*",0.1991778,"MEF2B","NA","NA","NA","K09261//MADS-box transcription enhancer factor 2B","XP_011846106.1//PREDICTED: myocyte-specific enhancer factor 2B-like isoform X1 [Mandrillus leucophaeus]","1//3"]
[6650,4759,27.79,31.94,0.200798478210671,1.01259797881011E-4,"*",{"v":2.3334e-05,"d":"2.33E-05"},"CAPN15","GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0004198//calcium-dependent cysteine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0003700//DNA binding transcription factor activity","NA","K08582//calpain-15 [EC:3.4.22.-]","XP_011520928.1//PREDICTED: calpain-15 isoform X2 [Homo sapiens]","2//1"]
[2171,751,101.3,116.34,0.199713035139448,0.00592070767501434,"*",1.938852E-3,"FABP5","GO:0070062//extracellular exosome;GO:0030667//secretory granule membrane;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0035578//azurophil granule lumen;GO:0005829//cytosol;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0008289//lipid binding;GO:0005504//fatty acid binding;GO:0005215//transporter activity","GO:0019433//triglyceride catabolic process;GO:0006006//glucose metabolic process;GO:0015758//glucose transport;GO:0008544//epidermis development;GO:0043312//neutrophil degranulation;GO:0006656//phosphatidylcholine biosynthetic process;GO:0006629//lipid metabolic process","K08754//fatty acid-binding protein 5, epidermal","XP_011910842.1//PREDICTED: fatty acid-binding protein, epidermal [Cercocebus atys]","2//1"]
[9513,3016,40.94,47,0.199149654428951,0.000216676569635111,"*",{"v":5.31586e-05,"d":"5.32E-05"},"FXR2","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005844//polysome","GO:0003729//mRNA binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity","GO:0017148//negative regulation of translation","K15516//fragile X mental retardation protein","XP_006151848.2//PREDICTED: fragile X mental retardation syndrome-related protein 2 [Tupaia chinensis]","3//A2MP1"]
[1209,2502,163.71,187.91,0.198899395108898,{"v":3.02748185147801E-12,"d":"3.03E-12"},"*",{"v":2.62872e-13,"d":"2.63E-13"},"CLPTM1","GO:0016020//membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016021//integral component of membrane","NA","GO:0033081//regulation of T cell differentiation in thymus;GO:0030154//cell differentiation;GO:0007275//multicellular organism development","K22016//mucin-3/17","NP_001285.1//cleft lip and palate transmembrane protein 1 isoform 2 [Homo sapiens];XP_007995351.1//PREDICTED: cleft lip and palate transmembrane protein 1 isoform X1 [Chlorocebus sabaeus];NP_001269104.1//cleft lip and palate transmembrane protein 1 isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[55101,1605,97.27,111.57,0.197882330867935,{"v":1.7088905826087E-5,"d":"1.71E-05"},"*",{"v":3.44474e-06,"d":"3.44E-06"},"DMAC2","GO:0005739//mitochondrion","NA","GO:0032981//mitochondrial respiratory chain complex I assembly","K18490//homeobox protein OTX2;K07554//ATP synthase, H+ transporting, mitochondrial F0 complex, subunit s;K14816//pre-60S factor REI1","NP_060505.2//distal membrane-arm assembly complex protein 2 isoform 4 [Homo sapiens];NP_001307769.1//distal membrane-arm assembly complex protein 2 isoform 9 [Homo sapiens];NP_001307767.1//distal membrane-arm assembly complex protein 2 isoform 7 [Homo sapiens];NP_001161342.1//distal membrane-arm assembly complex protein 2 isoform 6 [Homo sapiens];NP_001161339.1//distal membrane-arm assembly complex protein 2 isoform 1 [Homo sapiens];NP_001307768.1//distal membrane-arm assembly complex protein 2 isoform 8 [Homo sapiens];NP_001161340.1//distal membrane-arm assembly complex protein 2 isoform 2 [Homo sapiens];NP_001307770.1//distal membrane-arm assembly complex protein 2 isoform 10 [Homo sapiens];NP_001161341.1//distal membrane-arm assembly complex protein 2 isoform 3 [Homo sapiens];NP_001307773.1//distal membrane-arm assembly complex protein 2 isoform 11 [Homo sapiens];NP_001161343.1//distal membrane-arm assembly complex protein 2 isoform 5 [Homo sapiens]","1//3;2//1"]
[23582,3669,5.47,6.27,0.196924610009482,0.200175638490389,"*",0.1069174,"CCNDBP1","GO:0005654//nucleoplasm","NA","GO:0051726//regulation of cell cycle","K21626//cyclin-D1-binding protein 1","XP_011796513.1//PREDICTED: cyclin-D1-binding protein 1 isoform X2 [Colobus angolensis palliatus]",4]
[26284,1923,66.84,76.59,0.196444305067087,0.000207922298847041,"*",{"v":5.08026E-5,"d":"5.08E-05"},"ERAL1","GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0003723//RNA binding;GO:0043024//ribosomal small subunit binding;GO:0005525//GTP binding;GO:0019843//rRNA binding","GO:0000028//ribosomal small subunit assembly;GO:0070126//mitochondrial translational termination;GO:0070125//mitochondrial translational elongation","K03595//GTPase","AAG12978.1//ERA-W, partial [Homo sapiens];NP_001304915.1//GTPase Era, mitochondrial isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[2946,1478,5.09,5.83,0.195830227124801,0.587965762659847,"*",0.431754,"GSTM2","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0016529//sarcoplasmic reticulum","GO:0004364//glutathione transferase activity;GO:0043295//glutathione binding;GO:0004602//glutathione peroxidase activity;GO:0005102//receptor binding;GO:0042803//protein homodimerization activity;GO:0019899//enzyme binding","GO:0042178//xenobiotic catabolic process;GO:0014809//regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion;GO:0008152//metabolic process;GO:0043651//linoleic acid metabolic process;GO:0070458//cellular detoxification of nitrogen compound;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0006749//glutathione metabolic process;GO:0071313//cellular response to caffeine;GO:0055119//relaxation of cardiac muscle;GO:0060316//positive regulation of ryanodine-sensitive calcium-release channel activity;GO:0010881//regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion;GO:0060315//negative regulation of ryanodine-sensitive calcium-release channel activity;GO:0018916//nitrobenzene metabolic process;GO:1901687//glutathione derivative biosynthetic process","K00799//glutathione S-transferase [EC:2.5.1.18]","NP_000839.1//glutathione S-transferase Mu 2 isoform 1 [Homo sapiens];NP_001135840.1//glutathione S-transferase Mu 2 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[51371,1477,45.96,52.59,0.194409698834581,0.0108458702762827,"*",0.00378458,"POMP","GO:0000502//proteasome complex","NA","GO:0043248//proteasome assembly","K11599//proteasome maturation protein","XP_004854854.2//proteasome maturation protein [Heterocephalus glaber]",5]
[54923,1452,10.37,11.86,0.193688115732778,0.22707950356653,"*",0.1243578,"LIME1","GO:0019815//B cell receptor complex;GO:0005615//extracellular space;GO:0071008//U2-type post-mRNA release spliceosomal complex;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0019901//protein kinase binding","GO:0050853//B cell receptor signaling pathway;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0014066//regulation of phosphatidylinositol 3-kinase signaling;GO:0050852//T cell receptor signaling pathway;GO:0051279//regulation of release of sequestered calcium ion into cytosol;GO:0042345//regulation of NF-kappaB import into nucleus;GO:0043405//regulation of MAP kinase activity;GO:0000390//spliceosomal complex disassembly;GO:0002250//adaptive immune response","K16628//collagen, type VII, alpha;K06237//collagen, type IV, alpha;K19721//collagen, type V/XI/XXIV/XXVII, alpha;K19720//collagen, type III, alpha","XP_014198608.1//PREDICTED: lck-interacting transmembrane adapter 1 isoform X4 [Pan paniscus];NP_060276.2//lck-interacting transmembrane adapter 1 isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[57130,3887,20.61,23.56,0.192995034291204,0.00487302061143524,"*",0.001568616,"ATP13A1","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0046872//metal ion binding;GO:0005524//ATP binding;GO:0005388//calcium-transporting ATPase activity;GO:0016887//ATPase activity;GO:0015410//manganese-transporting ATPase activity","GO:0034220//ion transmembrane transport;GO:0006812//cation transport;GO:0006874//cellular calcium ion homeostasis","K14950//manganese-transporting P-type ATPase [EC:3.6.3.-]","NP_065143.2//manganese-transporting ATPase 13A1 [Homo sapiens]","2//1"]
[57463,5174,0.35,0.4,0.192645077942396,0.765521287911456,"*",0.6668,"AMIGO1","GO:0030425//dendrite;GO:0030424//axon;GO:0005887//integral component of plasma membrane;GO:0032809//neuronal cell body membrane;GO:0008076//voltage-gated potassium channel complex;GO:0043204//perikaryon","GO:0015459//potassium channel regulator activity","GO:0042552//myelination;GO:0007413//axonal fasciculation;GO:1901381//positive regulation of potassium ion transmembrane transport;GO:0050772//positive regulation of axonogenesis;GO:0051965//positive regulation of synapse assembly;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007409//axonogenesis;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules","K19511//peroxidase [EC:1.11.1.7]","OWK04833.1//AMIGO1 [Cervus elaphus hippelaphus]","3//A2MP1"]
[506,1857,432.36,494.03,0.192365594610411,{"v":1.01299377142857E-21,"d":"1.01E-21"},"*",{"v":4.35028e-23,"d":"4.35E-23"},"ATP5F1B","GO:0005759//mitochondrial matrix;GO:0016020//membrane;GO:0042645//mitochondrial nucleoid;GO:0005754//mitochondrial proton-transporting ATP synthase, catalytic core;GO:0045259//proton-transporting ATP synthase complex;GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0070062//extracellular exosome;GO:0031012//extracellular matrix;GO:0045261//proton-transporting ATP synthase complex, catalytic core F(1);GO:0005634//nucleus;GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0043209//myelin sheath;GO:0009986//cell surface;GO:0005743//mitochondrial inner membrane;GO:0031966//mitochondrial membrane","GO:0005524//ATP binding;GO:0043532//angiostatin binding;GO:0042288//MHC class I protein binding;GO:0005215//transporter activity;GO:0022857//transmembrane transporter activity;GO:0046961//proton-transporting ATPase activity, rotational mechanism;GO:0046933//proton-transporting ATP synthase activity, rotational mechanism","GO:0001649//osteoblast differentiation;GO:0042407//cristae formation;GO:0001525//angiogenesis;GO:0042776//mitochondrial ATP synthesis coupled proton transport;GO:0006091//generation of precursor metabolites and energy;GO:0051453//regulation of intracellular pH;GO:0006933//negative regulation of cell adhesion involved in substrate-bound cell migration;GO:0007005//mitochondrion organization;GO:0015986//ATP synthesis coupled proton transport;GO:0006754//ATP biosynthetic process;GO:0015992//proton transport;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0006629//lipid metabolic process","K02133//F-type H+-transporting ATPase subunit beta [EC:3.6.3.14]","NP_001677.2//ATP synthase subunit beta, mitochondrial precursor [Homo sapiens]","3//A2MP1"]
[5947,1418,1.41,1.61,0.191365525715823,0.681429970176368,"*",0.563564,"RBP1","GO:0044297//cell body;GO:0005654//nucleoplasm;GO:0005829//cytosol","GO:0008289//lipid binding;GO:0016918//retinal binding;GO:0005215//transporter activity;GO:0019841//retinol binding;GO:0005501//retinoid binding","GO:0001523//retinoid metabolic process;GO:0042572//retinol metabolic process;GO:0002138//retinoic acid biosynthetic process;GO:0006776//vitamin A metabolic process;GO:0033189//response to vitamin A;GO:0030852//regulation of granulocyte differentiation","K11447//histone demethylase [EC:1.14.11.-];K06210//nicotinamide mononucleotide adenylyltransferase [EC:2.7.7.1 2.7.7.18];K14622//retinol binding protein 2","NP_002890.2//retinol-binding protein 1 isoform a [Homo sapiens];NP_001124465.1//retinol-binding protein 1 isoform c [Homo sapiens];NP_001124464.1//retinol-binding protein 1 isoform b [Homo sapiens]","1//3;3//A2MP1"]
[286257,828,39.26,44.81,0.190760553686334,0.112776020734908,"*",0.053797,"PAXX","GO:0043564//Ku70:Ku80 complex;GO:0035861//site of double-strand break;GO:0070419//nonhomologous end joining complex;GO:0070062//extracellular exosome;GO:0005634//nucleus","GO:0032947//protein complex scaffold activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity","GO:0051103//DNA ligation involved in DNA repair;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0006974//cellular response to DNA damage stimulus","NA","NP_001316607.1//protein PAXX isoform 1 [Homo sapiens];NP_899064.1//protein PAXX isoform 2 [Homo sapiens]","1//3;2//1"]
[6560,4692,8.72,9.95,0.190368390654084,0.0737280137911703,"*",0.0329316,"SLC12A4","GO:0016021//integral component of membrane","GO:0015379//potassium:chloride symporter activity","NA","K14427//solute carrier family 12 (potassium/chloride transporter), member 4/5/6","XP_012516013.1//PREDICTED: solute carrier family 12 member 4 isoform X1 [Propithecus coquereli];XP_012323591.1//solute carrier family 12 member 4 isoform X3 [Aotus nancymaae];XP_008063936.1//solute carrier family 12 member 4 isoform X1 [Carlito syrichta];XP_012323590.1//solute carrier family 12 member 4 isoform X2 [Aotus nancymaae]","4;1//3"]
[2116,1087,1.21,1.38,0.189661219503575,0.652897259045578,"*",0.495906,"ETV2","GO:0005634//nucleus","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:2000382//positive regulation of mesoderm development;GO:0030154//cell differentiation;GO:0001890//placenta development;GO:0045603//positive regulation of endothelial cell differentiation;GO:0030218//erythrocyte differentiation;GO:0060803//BMP signaling pathway involved in mesodermal cell fate specification;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0001824//blastocyst development;GO:0048514//blood vessel morphogenesis;GO:0016055//Wnt signaling pathway;GO:0007219//Notch signaling pathway","K09432//ETS translocation variant 2","NP_001291478.1//ETS translocation variant 2 isoform 3 [Homo sapiens];XP_005258709.1//PREDICTED: ETS translocation variant 2 isoform X1 [Homo sapiens];NP_055024.2//ETS translocation variant 2 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[5937,4300,14.67,16.73,0.189568574364963,0.0150876169305219,"*",0.00546494,"RBMS1","NA","NA","NA","K03344//Dvl-binding protein IDAX;K20638//Rho GTPase-activating protein 17","XP_016289148.1//PREDICTED: RNA-binding motif, single-stranded-interacting protein 1 isoform X3 [Monodelphis domestica];XP_006766541.1//PREDICTED: RNA-binding motif, single-stranded-interacting protein 1 [Myotis davidii]","4;3//A2MP1"]
[83549,2196,11.43,13.03,0.189011680353656,0.162772398637967,"*",0.083791,"UCK1","GO:0005829//cytosol","GO:0004849//uridine kinase activity;GO:0005524//ATP binding;GO:0019206//nucleoside kinase activity","GO:0043097//pyrimidine nucleoside salvage;GO:0006206//pyrimidine nucleobase metabolic process;GO:0044206//UMP salvage;GO:0044211//CTP salvage","K00876//uridine kinase [EC:2.7.1.48]","XP_017354538.1//PREDICTED: uridine-cytidine kinase 1 isoform X2 [Cebus capucinus imitator];NP_001305448.1//uridine-cytidine kinase 1 isoform e [Homo sapiens];NP_001248379.1//uridine-cytidine kinase 1 isoform c [Homo sapiens];NP_001248380.1//uridine-cytidine kinase 1 isoform d [Homo sapiens];XP_017354537.1//PREDICTED: uridine-cytidine kinase 1 isoform X1 [Cebus capucinus imitator]","1//3;3//A2MP1;2//1"]
[2013,5220,15.31,17.45,0.188752753597227,0.00592362449770642,"*",0.001940178,"EMP2","GO:0005634//nucleus;GO:0016324//apical plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0005737//cytoplasm;GO:0000139//Golgi membrane;GO:0009986//cell surface;GO:0045121//membrane raft;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0045177//apical part of cell;GO:0005886//plasma membrane","GO:0005178//integrin binding;GO:0019900//kinase binding;GO:0019901//protein kinase binding","GO:0045022//early endosome to late endosome transport;GO:0001954//positive regulation of cell-matrix adhesion;GO:0016477//cell migration;GO:0070252//actin-mediated cell contraction;GO:0003093//regulation of glomerular filtration;GO:0043534//blood vessel endothelial cell migration;GO:0007566//embryo implantation;GO:0007015//actin filament organization;GO:0008283//cell proliferation;GO:0001765//membrane raft assembly;GO:0010594//regulation of endothelial cell migration;GO:2001046//positive regulation of integrin-mediated signaling pathway;GO:0001913//T cell mediated cytotoxicity;GO:0032060//bleb assembly;GO:0072659//protein localization to plasma membrane;GO:0032147//activation of protein kinase activity;GO:0008219//cell death;GO:0007160//cell-matrix adhesion;GO:0007155//cell adhesion;GO:0045765//regulation of angiogenesis;GO:2001212//regulation of vasculogenesis;GO:0043549//regulation of kinase activity;GO:0034394//protein localization to cell surface;GO:0008284//positive regulation of cell proliferation","K19289//peripheral myelin protein 22","NP_001415.1//epithelial membrane protein 2 precursor [Homo sapiens]",5]
[2621,2551,3.16,3.6,0.188072348152572,0.487246301804265,"*",0.334734,"GAS6","GO:0070062//extracellular exosome;GO:0005788//endoplasmic reticulum lumen;GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process;GO:0005245//voltage-gated calcium channel activity;GO:0048018//receptor ligand activity;GO:0030971//receptor tyrosine kinase binding;GO:0030296//protein tyrosine kinase activator activity;GO:0060090//molecular adaptor activity;GO:0005509//calcium ion binding;GO:0001786//phosphatidylserine binding","GO:0031100//animal organ regeneration;GO:0019079//viral genome replication;GO:0010804//negative regulation of tumor necrosis factor-mediated signaling pathway;GO:0009267//cellular response to starvation;GO:0035690//cellular response to drug;GO:0007596//blood coagulation;GO:0043433//negative regulation of DNA binding transcription factor activity;GO:0043491//protein kinase B signaling;GO:0032825//positive regulation of natural killer cell differentiation;GO:0050711//negative regulation of interleukin-1 secretion;GO:0071363//cellular response to growth factor stimulus;GO:0035457//cellular response to interferon-alpha;GO:0045892//negative regulation of transcription, DNA-templated;GO:0033159//negative regulation of protein import into nucleus, translocation;GO:2000510//positive regulation of dendritic cell chemotaxis;GO:0010934//macrophage cytokine production;GO:0048146//positive regulation of fibroblast proliferation;GO:1900165//negative regulation of interleukin-6 secretion;GO:0010628//positive regulation of gene expression;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:0043277//apoptotic cell clearance;GO:0018105//peptidyl-serine phosphorylation;GO:0001764//neuron migration;GO:0035754//B cell chemotaxis;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0032148//activation of protein kinase B activity;GO:0051897//positive regulation of protein kinase B signaling;GO:0032720//negative regulation of tumor necrosis factor production;GO:0097241//hematopoietic stem cell migration to bone marrow;GO:0050766//positive regulation of phagocytosis;GO:0001961//positive regulation of cytokine-mediated signaling pathway;GO:0070168//negative regulation of biomineral tissue development;GO:0071307//cellular response to vitamin K;GO:0046827//positive regulation of protein export from nucleus;GO:2000270//negative regulation of fibroblast apoptotic process;GO:0072659//protein localization to plasma membrane;GO:0031589//cell-substrate adhesion;GO:1900142//negative regulation of oligodendrocyte apoptotic process;GO:0019064//fusion of virus membrane with host plasma membrane;GO:2000669//negative regulation of dendritic cell apoptotic process;GO:0097028//dendritic cell differentiation;GO:0046813//receptor-mediated virion attachment to host cell;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0032689//negative regulation of interferon-gamma production","K05464//growth arrest-specific 6","NP_000811.1//growth arrest-specific protein 6 precursor [Homo sapiens]","3//A2MP1"]
[79042,2270,52.03,59.26,0.18771491898459,0.000875820347432708,"*",2.42394E-4,"TSEN34","GO:0000214//tRNA-intron endonuclease complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus","GO:0016829//lyase activity;GO:0000213//tRNA-intron endonuclease activity","GO:0006397//mRNA processing;GO:0006388//tRNA splicing, via endonucleolytic cleavage and ligation;GO:0000379//tRNA-type intron splice site recognition and cleavage","K15323//tRNA-splicing endonuclease subunit Sen34 [EC:3.1.27.9]","NP_001269262.1//tRNA-splicing endonuclease subunit Sen34 isoform 2 [Homo sapiens];BAB15284.1//unnamed protein product [Homo sapiens]","1//3;4;3//A2MP1"]
[91120,3164,0.36,0.41,0.187627003175771,0.804076696801406,"*",0.716038,"ZNF682","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_012364882.1//PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 726 [Nomascus leucogenys]","1//3;2//1"]
[280636,1447,19.68,22.4,0.186768511605727,0.139721284577739,"*",0.0697032,"SELENOH","NA","NA","NA","K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K02927//large subunit ribosomal protein L40e;K15696//RING finger protein 113B;K17985//activating molecule in BECN1-regulated autophagy protein 1;K01064//wingless-type MMTV integration site family, member 9","XP_018891860.1//PREDICTED: selenoprotein H [Gorilla gorilla gorilla]","1//3;3//A2MP1"]
[1102,2892,0.29,0.33,0.186413124230881,0.890199570717266,"*",0.82823,"RCBTB2","GO:0001669//acrosomal vesicle","GO:0005087//Ran guanyl-nucleotide exchange factor activity","NA","K11494//RCC1 and BTB domain-containing protein","NP_001273761.1//RCC1 and BTB domain-containing protein 2 isoform 4 [Homo sapiens];NP_001339358.1//RCC1 and BTB domain-containing protein 2 isoform 5 precursor [Homo sapiens];NP_001259.1//RCC1 and BTB domain-containing protein 2 isoform 2 [Homo sapiens];BAG60659.1//unnamed protein product [Homo sapiens];NP_001339359.1//RCC1 and BTB domain-containing protein 2 isoform 6 [Homo sapiens];BAD92780.1//RCC1-like G exchanging factor RLG variant, partial [Homo sapiens];NP_001339360.1//RCC1 and BTB domain-containing protein 2 isoform 7 [Homo sapiens];NP_001273759.1//RCC1 and BTB domain-containing protein 2 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[4817,1760,24.19,27.52,0.186069700722173,0.26571824171123,"*",0.1524212,"NIT1","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005739//mitochondrion","GO:0016810//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds;GO:0000257//nitrilase activity","GO:0006807//nitrogen compound metabolic process","K13566//omega-amidase [EC:3.5.1.3];K20649//Rho GTPase-activating protein 39","NP_001172021.1//nitrilase homolog 1 isoform 2 [Homo sapiens];XP_005245272.1//PREDICTED: nitrilase homolog 1 isoform X1 [Homo sapiens];NP_001172022.1//nitrilase homolog 1 isoform 3 [Homo sapiens];XP_005245271.1//PREDICTED: nitrilase homolog 1 isoform X2 [Homo sapiens]","1//3;2//1"]
[1059,2856,102.65,116.72,0.185318160921926,{"v":5.28609454202247e-08,"d":"5.29E-08"},"*",{"v":7.36294e-09,"d":"7.36E-09"},"CENPB","GO:0016604//nuclear body;GO:0000780//condensed nuclear chromosome, centromeric region;GO:0031618//nuclear pericentric heterochromatin","GO:0003696//satellite DNA binding;GO:0003682//chromatin binding","NA","K11496//centromere protein B;K19607//X-linked retinitis pigmentosa GTPase regulator","XP_020732714.1//major centromere autoantigen B [Odocoileus virginianus texanus]",5]
[100507436,1613,20.4,23.19,0.184933667787146,0.15435325905019,"*",0.078742,"MICA","GO:0016021//integral component of membrane","NA","NA","K07985//MHC class I-related protein","NP_001170990.1//MHC class I polypeptide-related sequence A isoform 2 (MICA*00801) precursor [Homo sapiens];NP_001276083.1//MHC class I polypeptide-related sequence A isoform 4 (MICA*00801) [Homo sapiens];ARR96089.1//MHC class I chain-related protein A [Homo sapiens]","1//3;2//1"]
[4157,3115,9.89,11.24,0.184599609461815,0.126446842709943,"*",0.0614582,"MC1R","NA","NA","NA","K04199//melanocortin 1 receptor","Q864K8.1//RecName: Full=Melanocyte-stimulating hormone receptor; Short=MSH-R; AltName: Full=Melanocortin receptor 1; Short=MC1-R","3//A2MP1"]
[6419,1403,10.46,11.88,0.183651984553824,0.216157029197417,"*",0.1173478,"SETMAR","GO:0035861//site of double-strand break;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005694//chromosome","GO:0044547//DNA topoisomerase binding;GO:0003677//DNA binding;GO:0042800//histone methyltransferase activity (H3-K4 specific);GO:0000014//single-stranded DNA endodeoxyribonuclease activity;GO:0042803//protein homodimerization activity;GO:0003690//double-stranded DNA binding;GO:0003676//nucleic acid binding;GO:0003697//single-stranded DNA binding;GO:0046975//histone methyltransferase activity (H3-K36 specific);GO:0008270//zinc ion binding;GO:0004519//endonuclease activity;GO:0018024//histone-lysine N-methyltransferase activity","GO:0015074//DNA integration;GO:0010452//histone H3-K36 methylation;GO:2001251//negative regulation of chromosome organization;GO:0044774//mitotic DNA integrity checkpoint;GO:0051568//histone H3-K4 methylation;GO:2001034//positive regulation of double-strand break repair via nonhomologous end joining;GO:0000729//DNA double-strand break processing;GO:0008283//cell proliferation;GO:0031297//replication fork processing;GO:2000373//positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0071157//negative regulation of cell cycle arrest;GO:0000737//DNA catabolic process, endonucleolytic;GO:0097676//histone H3-K36 dimethylation;GO:0006303//double-strand break repair via nonhomologous end joining","K11433//histone-lysine N-methyltransferase SETMAR [EC:2.1.1.43]","AAH08931.2//SETMAR protein, partial [Homo sapiens];NP_006506.3//histone-lysine N-methyltransferase SETMAR isoform 1 [Homo sapiens];NP_001263254.1//histone-lysine N-methyltransferase SETMAR isoform 3 [Homo sapiens];NP_001307606.1//histone-lysine N-methyltransferase SETMAR isoform 6 [Homo sapiens];NP_001307607.1//histone-lysine N-methyltransferase SETMAR isoform 7 [Homo sapiens];NP_001230652.1//histone-lysine N-methyltransferase SETMAR isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[9277,2363,19.7,22.37,0.18336962671538,0.0536139065573771,"*",0.0229304,"WDR46","GO:0005654//nucleoplasm;GO:0030686//90S preribosome;GO:0032040//small-subunit processome;GO:0005730//nucleolus","GO:0003723//RNA binding","GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:1903955//positive regulation of protein targeting to mitochondrion;GO:0006364//rRNA processing","K14768//U3 small nucleolar RNA-associated protein 7","NP_001157739.1//WD repeat-containing protein 46 isoform 2 [Homo sapiens];NP_005443.3//WD repeat-containing protein 46 isoform 1 [Homo sapiens]","1//3;5"]
[55210,2495,20.14,22.86,0.182761720207694,0.113284884563934,"*",0.0540752,"ATAD3A","GO:0042645//mitochondrial nucleoid;GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion","GO:0005524//ATP binding","GO:0043066//negative regulation of apoptotic process;GO:0016049//cell growth","K17681//ATPase family AAA domain-containing protein 3A/B","XP_011540546.1//PREDICTED: ATPase family AAA domain-containing protein 3B isoform X4 [Homo sapiens];NP_114127.3//ATPase family AAA domain-containing protein 3B isoform AAA-TOB3l [Homo sapiens]","4;2//1"]
[311,2491,136.99,155.45,0.182380033544018,{"v":1.64331475585284E-8,"d":"1.64E-08"},"*",{"v":2.15316E-9,"d":"2.15E-09"},"ANXA11","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005654//nucleoplasm;GO:0005635//nuclear envelope;GO:0042581//specific granule;GO:0042470//melanosome;GO:0005737//cytoplasm;GO:0030496//midbody;GO:0045335//phagocytic vesicle;GO:0005829//cytosol;GO:0005819//spindle;GO:0042582//azurophil granule","GO:0003723//RNA binding;GO:0005544//calcium-dependent phospholipid binding;GO:0044548//S100 protein binding;GO:0008429//phosphatidylethanolamine binding;GO:0005509//calcium ion binding;GO:0048306//calcium-dependent protein binding;GO:0023026//MHC class II protein complex binding","GO:0051592//response to calcium ion;GO:0032506//cytokinetic process;GO:0006909//phagocytosis","K17095//annexin A7/11","NP_001148.1//annexin A11 isoform 1 [Homo sapiens];BAD93007.1//annexin A11 variant, partial [Homo sapiens]","1//3;2//1"]
[147184,2067,8.42,9.55,0.181680499856715,0.29374793605661,"*",0.1715154,"TMEM99","GO:0016021//integral component of membrane","NA","NA","K07604//type I keratin, acidic","NP_660317.2//transmembrane protein 99 precursor [Homo sapiens]","1//3;3//A2MP1"]
[5437,1322,22.31,25.29,0.180876523419098,0.228460205538046,"*",0.127059,"POLR2H","GO:0005665//DNA-directed RNA polymerase II, core complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0032993//protein-DNA complex;GO:0005666//DNA-directed RNA polymerase III complex;GO:0005736//DNA-directed RNA polymerase I complex","GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0003697//single-stranded DNA binding","GO:0032481//positive regulation of type I interferon production;GO:0045815//positive regulation of gene expression, epigenetic;GO:0006361//transcription initiation from RNA polymerase I promoter;GO:0042795//snRNA transcription from RNA polymerase II promoter;GO:0006370//7-methylguanosine mRNA capping;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0035019//somatic stem cell population maintenance;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0006362//transcription elongation from RNA polymerase I promoter;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0016070//RNA metabolic process;GO:0006363//termination of RNA polymerase I transcription;GO:0000398//mRNA splicing, via spliceosome;GO:0060964//regulation of gene silencing by miRNA;GO:0050434//positive regulation of viral transcription;GO:0006351//transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006383//transcription from RNA polymerase III promoter","K03016//DNA-directed RNA polymerases I, II, and III subunit RPABC3","XP_016797908.1//PREDICTED: DNA-directed RNA polymerases I, II, and III subunit RPABC3 isoform X1 [Pan troglodytes];XP_526411.3//PREDICTED: DNA-directed RNA polymerases I, II, and III subunit RPABC3 isoform X2 [Pan troglodytes];NP_001265627.1//DNA-directed RNA polymerases I, II, and III subunit RPABC3 isoform 1 [Homo sapiens];KFO04228.1//DNA-directed RNA polymerases I, II, and III subunit RPABC3, partial [Balearica regulorum gibbericeps]","1//3;4;2//1"]
[6636,806,99.94,113.27,0.180631685171711,0.0111475577706324,"*",0.0039066,"SNRPF","NA","NA","NA","K11098//small nuclear ribonucleoprotein F","ELK10363.1//Small nuclear ribonucleoprotein F [Pteropus alecto]","2//1"]
[84962,4042,21.34,24.18,0.180254068424699,0.015006166779661,"*",0.00543168,"AJUBA","GO:0005634//nucleus;GO:0005815//microtubule organizing center;GO:0005925//focal adhesion;GO:0000932//P-body;GO:0030027//lamellipodium;GO:0005912//adherens junction;GO:0005667//transcription factor complex;GO:0005911//cell-cell junction;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane","GO:0051015//actin filament binding;GO:0046872//metal ion binding;GO:0003714//transcription corepressor activity;GO:0003682//chromatin binding;GO:0045294//alpha-catenin binding","GO:0030032//lamellipodium assembly;GO:0006355//regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0030334//regulation of cell migration;GO:0048041//focal adhesion assembly;GO:1900037//regulation of cellular response to hypoxia;GO:0043406//positive regulation of MAP kinase activity;GO:0006351//transcription, DNA-templated;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0035331//negative regulation of hippo signaling;GO:0033673//negative regulation of kinase activity;GO:0001666//response to hypoxia;GO:0046474//glycerophospholipid biosynthetic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043087//regulation of GTPase activity;GO:0031334//positive regulation of protein complex assembly;GO:0035313//wound healing, spreading of epidermal cells;GO:0007010//cytoskeleton organization;GO:0034613//cellular protein localization;GO:0031328//positive regulation of cellular biosynthetic process;GO:0035195//gene silencing by miRNA;GO:0000086//G2/M transition of mitotic cell cycle;GO:2000637//positive regulation of gene silencing by miRNA","K16682//LIM domain-containing protein","XP_020018451.1//LIM domain-containing protein ajuba-like, partial [Castor canadensis];NP_001276026.1//LIM domain-containing protein ajuba isoform 3 [Homo sapiens];NP_116265.1//LIM domain-containing protein ajuba isoform 1 [Homo sapiens]","1//3;2//1;5"]
[3705,3282,45.88,51.96,0.179536039432056,0.00031550133102253,"*",{"v":7.9774e-05,"d":"7.98E-05"},"ITPK1","GO:0016324//apical plasma membrane;GO:0005829//cytosol;GO:0005622//intracellular","GO:0000287//magnesium ion binding;GO:0052825//inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity;GO:0052830//inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity;GO:0052725//inositol-1,3,4-trisphosphate 6-kinase activity;GO:0005524//ATP binding;GO:0016853//isomerase activity;GO:0047325//inositol tetrakisphosphate 1-kinase activity;GO:0003824//catalytic activity;GO:0052831//inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity;GO:0052659//inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity;GO:0052835//inositol-3,4,6-trisphosphate 1-kinase activity;GO:0052726//inositol-1,3,4-trisphosphate 5-kinase activity","GO:0007165//signal transduction;GO:0043647//inositol phosphate metabolic process;GO:0007596//blood coagulation;GO:0021915//neural tube development;GO:0032957//inositol trisphosphate metabolic process","K00913//inositol-1,3,4-trisphosphate 5/6-kinase / inositol-tetrakisphosphate 1-kinase [EC:2.7.1.159 2.7.1.134]","XP_008956466.1//PREDICTED: inositol-tetrakisphosphate 1-kinase isoform X2 [Pan paniscus];NP_055031.2//inositol-tetrakisphosphate 1-kinase isoform a [Homo sapiens]","2//1;5"]
[84418,926,104.04,117.77,0.178833778380039,0.00524304029835749,"*",0.001698556,"CYSTM1","NA","NA","NA","NA","XP_008984227.2//PREDICTED: cysteine-rich and transmembrane domain-containing protein 1 isoform X1 [Callithrix jacchus]","3//A2MP1"]
[4715,735,128.48,145.36,0.178086526716802,0.00652519009271523,"*",0.00215886,"NDUFB9","GO:0070062//extracellular exosome;GO:0005747//mitochondrial respiratory chain complex I;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0008137//NADH dehydrogenase (ubiquinone) activity","GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0007605//sensory perception of sound","K03965//NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 9","XP_004090853.2//PREDICTED: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 isoform X1 [Nomascus leucogenys]","1//3;2//1"]
[9212,1262,119.34,134.93,0.177133467165769,0.0201738763072821,"*",0.00757878,"AURKB","GO:0010369//chromocenter;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0051233//spindle midzone;GO:1990023//mitotic spindle midzone;GO:0000780//condensed nuclear chromosome, centromeric region;GO:0000779//condensed chromosome, centromeric region;GO:0032133//chromosome passenger complex;GO:0030496//midbody;GO:0005829//cytosol;GO:0005819//spindle;GO:0031616//spindle pole centrosome;GO:0005876//spindle microtubule","GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0046872//metal ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0019900//kinase binding;GO:0035174//histone serine kinase activity","GO:0051983//regulation of chromosome segregation;GO:0016925//protein sumoylation;GO:0051973//positive regulation of telomerase activity;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0051256//mitotic spindle midzone assembly;GO:0016570//histone modification;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0034644//cellular response to UV;GO:0007051//spindle organization;GO:0034501//protein localization to kinetochore;GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0002903//negative regulation of B cell apoptotic process;GO:0008283//cell proliferation;GO:0032091//negative regulation of protein binding;GO:0043988//histone H3-S28 phosphorylation;GO:0032467//positive regulation of cytokinesis;GO:1904355//positive regulation of telomere capping;GO:0036089//cleavage furrow formation;GO:0044878//mitotic cytokinesis checkpoint;GO:0031577//spindle checkpoint;GO:0009838//abscission;GO:0006468//protein phosphorylation;GO:0046777//protein autophosphorylation;GO:0007568//aging;GO:0008608//attachment of spindle microtubules to kinetochore;GO:1901796//regulation of signal transduction by p53 class mediator;GO:0007062//sister chromatid cohesion;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0032466//negative regulation of cytokinesis","K11479//aurora kinase B [EC:2.7.11.1]","EAW90079.1//aurora kinase B, isoform CRA_e [Homo sapiens];XP_020031087.1//aurora kinase B isoform X4 [Castor canadensis];AAH13300.2//AURKB protein, partial [Homo sapiens];XP_016802256.1//PREDICTED: aurora kinase B isoform X1 [Pan troglodytes];NP_001300882.1//aurora kinase B isoform 5 [Homo sapiens];NP_004208.2//aurora kinase B isoform 1 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[79759,2700,11.95,13.51,0.177017056457574,0.285344631533477,"*",0.165412,"ZNF668","GO:0005634//nucleus","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0003700//DNA binding transcription factor activity;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","XP_003124524.1//zinc finger protein 668 [Sus scrofa]","4;1//3"]
[64425,1884,22.87,25.85,0.176707914790624,0.0783281578742348,"*",0.0352462,"POLR1E","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0001650//fibrillar center;GO:0005736//DNA-directed RNA polymerase I complex","GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0003677//DNA binding;GO:0001179//RNA polymerase I transcription factor binding","GO:0006363//termination of RNA polymerase I transcription;GO:0006362//transcription elongation from RNA polymerase I promoter;GO:0001189//RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript;GO:0045815//positive regulation of gene expression, epigenetic;GO:0006361//transcription initiation from RNA polymerase I promoter;GO:0006351//transcription, DNA-templated;GO:0009303//rRNA transcription","K03005//DNA-directed RNA polymerase I subunit RPA49","NP_001269695.1//DNA-directed RNA polymerase I subunit RPA49 isoform 2 [Homo sapiens];NP_071935.1//DNA-directed RNA polymerase I subunit RPA49 isoform 1 [Homo sapiens]","1//3;2//1"]
[284338,1532,16.74,18.9,0.175086706558091,0.203583944940407,"*",0.1090692,"PRR19","NA","NA","NA","K16795//platelet-activating factor acetylhydrolase IB subunit beta/gamma [EC:3.1.1.47]","XP_005258836.2//PREDICTED: proline-rich protein 19 isoform X1 [Homo sapiens]","2//1"]
[11156,2764,3.18,3.59,0.174957078538696,0.579967060135541,"*",0.42323,"PTP4A3","GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0005769//early endosome;GO:0005737//cytoplasm","GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0004727//prenylated protein tyrosine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0016791//phosphatase activity","GO:0043542//endothelial cell migration;GO:0006355//regulation of transcription, DNA-templated;GO:1904951//positive regulation of establishment of protein localization;GO:1990830//cellular response to leukemia inhibitory factor;GO:0007219//Notch signaling pathway;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:1900746//regulation of vascular endothelial growth factor signaling pathway;GO:0043117//positive regulation of vascular permeability","K18041//protein tyrosine phosphatase type IVA [EC:3.1.3.48]","NP_009010.2//protein tyrosine phosphatase type IVA 3 isoform 2 [Homo sapiens];NP_116000.1//protein tyrosine phosphatase type IVA 3 isoform 1 [Homo sapiens]","3//A2MP1;2//1"]
[55869,2169,7.49,8.45,0.173985622710796,0.382156464081755,"*",0.238782,"HDAC8","GO:0005634//nucleus;GO:0005886//plasma membrane","GO:0004407//histone deacetylase activity;GO:0051879//Hsp90 protein binding;GO:0046872//metal ion binding;GO:0032041//NAD-dependent histone deacetylase activity (H3-K14 specific);GO:0030544//Hsp70 protein binding","GO:0031397//negative regulation of protein ubiquitination;GO:0071922//regulation of cohesin loading;GO:0007062//sister chromatid cohesion;GO:0031647//regulation of protein stability;GO:0006355//regulation of transcription, DNA-templated;GO:0032204//regulation of telomere maintenance;GO:0006351//transcription, DNA-templated","K11405//histone deacetylase 8 [EC:3.5.1.98]","XP_003317568.1//PREDICTED: histone deacetylase 8 isoform X12 [Pan troglodytes];EAW71821.1//histone deacetylase 8, isoform CRA_a [Homo sapiens];XP_011853603.1//PREDICTED: histone deacetylase 8 isoform X4 [Mandrillus leucophaeus];XP_016798636.1//PREDICTED: histone deacetylase 8 isoform X10 [Pan troglodytes];XP_009196076.1//histone deacetylase 8 isoform X3 [Papio anubis];EAW71824.1//histone deacetylase 8, isoform CRA_d [Homo sapiens]","1//3;2//1"]
[10312,2607,66.92,75.46,0.173274654771757,0.000468652408321377,"*",1.226934E-4,"TCIRG1","GO:0005765//lysosomal membrane;GO:0010008//endosome membrane;GO:0000220//vacuolar proton-transporting V-type ATPase, V0 domain;GO:0016324//apical plasma membrane;GO:0101003//ficolin-1-rich granule membrane;GO:0030670//phagocytic vesicle membrane;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0016471//vacuolar proton-transporting V-type ATPase complex","GO:0015078//hydrogen ion transmembrane transporter activity;GO:0051117//ATPase binding;GO:0005215//transporter activity;GO:0046961//proton-transporting ATPase activity, rotational mechanism","GO:0008286//insulin receptor signaling pathway;GO:0034220//ion transmembrane transport;GO:0070072//vacuolar proton-transporting V-type ATPase complex assembly;GO:0090383//phagosome acidification;GO:0007035//vacuolar acidification;GO:0006968//cellular defense response;GO:0015986//ATP synthesis coupled proton transport;GO:0015991//ATP hydrolysis coupled proton transport;GO:0007039//protein catabolic process in the vacuole;GO:0033572//transferrin transport;GO:0043312//neutrophil degranulation;GO:0015992//proton transport;GO:0016236//macroautophagy;GO:0008284//positive regulation of cell proliferation","K02154//V-type H+-transporting ATPase subunit a","NP_006010.2//V-type proton ATPase 116 kDa subunit a isoform 3 isoform a [Homo sapiens];NP_006044.1//V-type proton ATPase 116 kDa subunit a isoform 3 isoform b [Homo sapiens]","1//3;3//A2MP1"]
[23180,3033,1.02,1.15,0.17306470897288,0.696060444210526,"*",0.579542,"RFTN1","GO:0070062//extracellular exosome;GO:0005768//endosome;GO:0045121//membrane raft;GO:0043234//protein complex;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0003725//double-stranded RNA binding","GO:0050853//B cell receptor signaling pathway;GO:0050852//T cell receptor signaling pathway;GO:0002457//T cell antigen processing and presentation;GO:0032620//interleukin-17 production;GO:0043330//response to exogenous dsRNA;GO:0033227//dsRNA transport;GO:0032596//protein transport into membrane raft;GO:1903044//protein localization to membrane raft;GO:0001765//membrane raft assembly;GO:0040007//growth;GO:0034138//toll-like receptor 3 signaling pathway","K08379//prokineticin receptor 1","AAH51336.1//Raftlin, lipid raft linker 1, partial [Homo sapiens]","1//3"]
[146429,1860,1.34,1.51,0.172315548867307,0.732659632650041,"*",0.619784,"SLC22A31","NA","NA","NA","K08213//MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 17","A6NKX4.3//RecName: Full=Putative solute carrier family 22 member 31","1//3"]
[5025,2054,9.61,10.82,0.171092163053065,0.308159994366197,"*",0.1821682,"P2RX4","GO:0016020//membrane;GO:0005765//lysosomal membrane;GO:0070062//extracellular exosome;GO:0098794//postsynapse;GO:0030054//cell junction;GO:0005639//integral component of nuclear inner membrane;GO:0043195//terminal bouton;GO:0014069//postsynaptic density;GO:0048471//perinuclear region of cytoplasm;GO:0043025//neuronal cell body;GO:0005887//integral component of plasma membrane;GO:0043197//dendritic spine;GO:0005886//plasma membrane","GO:0004931//extracellularly ATP-gated cation channel activity;GO:0005524//ATP binding;GO:0005102//receptor binding;GO:0042803//protein homodimerization activity;GO:0045296//cadherin binding;GO:0005507//copper ion binding;GO:0008144//drug binding;GO:0008270//zinc ion binding;GO:0001614//purinergic nucleotide receptor activity","GO:0033198//response to ATP;GO:0008217//regulation of blood pressure;GO:2001028//positive regulation of endothelial cell chemotaxis;GO:0050850//positive regulation of calcium-mediated signaling;GO:0002028//regulation of sodium ion transport;GO:0007596//blood coagulation;GO:0034220//ion transmembrane transport;GO:0097190//apoptotic signaling pathway;GO:0051260//protein homooligomerization;GO:0032308//positive regulation of prostaglandin secretion;GO:0019228//neuronal action potential;GO:0071318//cellular response to ATP;GO:0019233//sensory perception of pain;GO:0055119//relaxation of cardiac muscle;GO:0035590//purinergic nucleotide receptor signaling pathway;GO:0006810//transport;GO:0007165//signal transduction;GO:0055117//regulation of cardiac muscle contraction;GO:0001894//tissue homeostasis;GO:0010614//negative regulation of cardiac muscle hypertrophy;GO:0034405//response to fluid shear stress;GO:0051899//membrane depolarization;GO:0042118//endothelial cell activation;GO:0010524//positive regulation of calcium ion transport into cytosol;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0051928//positive regulation of calcium ion transport","K05218//P2X purinoceptor 4","XP_017399747.1//PREDICTED: P2X purinoceptor 4 [Cebus capucinus imitator]","1//3;2//1"]
[7419,1554,92,103.58,0.171039697299111,0.000795214233280073,"*",2.18094E-4,"VDAC3","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005743//mitochondrial inner membrane;GO:0046930//pore complex;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane","GO:0015288//porin activity;GO:0008308//voltage-gated anion channel activity;GO:0000166//nucleotide binding","GO:1902017//regulation of cilium assembly;GO:0015853//adenine transport;GO:0007612//learning;GO:0007270//neuron-neuron synaptic transmission;GO:0001662//behavioral fear response","K15041//voltage-dependent anion channel protein 3","NP_005653.3//voltage-dependent anion-selective channel protein 3 isoform 1 [Homo sapiens];NP_001129166.1//voltage-dependent anion-selective channel protein 3 isoform 2 [Homo sapiens]","6;2//1"]
[112970,1712,7.91,8.9,0.170127641380968,0.400244049879169,"*",0.259204,"KTI12","NA","GO:0005524//ATP binding","NA","K15456//protein KTI12","XP_004089847.1//PREDICTED: protein KTI12 homolog isoform X1 [Nomascus leucogenys]","2//1"]
[84074,5411,0.48,0.54,0.169925001442313,0.732843485751767,"*",0.629482,"QRICH2","NA","NA","NA","K19926//zona pellucida sperm-binding protein 1","XP_016880695.1//PREDICTED: glutamine-rich protein 2 isoform X2 [Homo sapiens]","2//1"]
[4858,7673,0.16,0.18,0.169925001442312,0.814267720995053,"*",0.731536,"NOVA2","GO:0005634//nucleus","GO:0003723//RNA binding","GO:0000398//mRNA splicing, via spliceosome;GO:0051252//regulation of RNA metabolic process","K14944//RNA-binding protein Nova","EAW57397.1//neuro-oncological ventral antigen 2 [Homo sapiens]","3//A2MP1"]
[112770,1602,57.32,64.46,0.169365578797399,0.0196252152591107,"*",0.00734932,"GLMP","GO:0005765//lysosomal membrane;GO:0005634//nucleus;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005764//lysosome","GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0044212//transcription regulatory region DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0004879//nuclear receptor activity","GO:0045944//positive regulation of transcription from RNA polymerase II promoter","NA","AAH11575.1//C1orf85 protein, partial [Homo sapiens];XP_007974957.1//PREDICTED: lysosomal protein NCU-G1 isoform X4 [Chlorocebus sabaeus];NP_001243534.1//glycosylated lysosomal membrane protein isoform 3 [Homo sapiens];NP_001243533.1//glycosylated lysosomal membrane protein isoform 2 precursor [Homo sapiens];NP_653181.1//glycosylated lysosomal membrane protein isoform 1 precursor [Homo sapiens]","1//3;2//1"]
[100462977,1555,426.31,479.24,0.168845431243319,{"v":5.12063391708126e-14,"d":"5.12E-14"},"*",{"v":3.86596e-15,"d":"3.87E-15"},"MTRNR2L1","NA","NA","NA","K22237//Rab effector MyRIP","XP_012365851.1//PREDICTED: rab effector MyRIP [Nomascus leucogenys]","1//3"]
[11072,1508,29.85,33.54,0.168151757412179,0.0896707462605385,"*",0.041282,"DUSP14","NA","GO:0017017//MAP kinase tyrosine/serine/threonine phosphatase activity;GO:0003723//RNA binding;GO:0004725//protein tyrosine phosphatase activity","GO:0035335//peptidyl-tyrosine dephosphorylation","K14165//atypical dual specificity phosphatase [EC:3.1.3.16 3.1.3.48]","KFO32189.1//Dual specificity protein phosphatase 14 [Fukomys damarensis]","3//A2MP1"]
[51154,2273,38.67,43.42,0.167144961532337,0.0125707701003698,"*",0.0044691,"MRTO4","GO:0005730//nucleolus;GO:0005737//cytoplasm","GO:0003723//RNA binding","GO:0000027//ribosomal large subunit assembly;GO:0006364//rRNA processing;GO:0000956//nuclear-transcribed mRNA catabolic process","K14815//mRNA turnover protein 4","NP_057267.2//mRNA turnover protein 4 homolog [Homo sapiens]","3//A2MP1"]
[79034,2195,20.29,22.77,0.166365426379964,0.0952223697746593,"*",0.0441776,"C7orf26","NA","NA","NA","K04594//latrophilin 3","NP_001289968.1//uncharacterized protein C7orf26 isoform 2 [Homo sapiens];NP_076972.2//uncharacterized protein C7orf26 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[90410,1101,15.59,17.48,0.165084256802814,0.645775080634501,"*",0.489324,"IFT20","GO:0030992//intraciliary transport particle B;GO:0005929//cilium;GO:0005801//cis-Golgi network;GO:0000139//Golgi membrane;GO:0097542//ciliary tip;GO:0031514//motile cilium;GO:0032420//stereocilium;GO:1902636//kinociliary basal body;GO:0070062//extracellular exosome;GO:0032391//photoreceptor connecting cilium;GO:0005813//centrosome;GO:0005902//microvillus;GO:0001750//photoreceptor outer segment;GO:0005814//centriole;GO:0005794//Golgi apparatus;GO:0044292//dendrite terminus;GO:0097546//ciliary base","GO:0002046//opsin binding;GO:0017137//Rab GTPase binding","GO:0008542//visual learning;GO:0034067//protein localization to Golgi apparatus;GO:0001822//kidney development;GO:1902017//regulation of cilium assembly;GO:0061512//protein localization to cilium;GO:0060828//regulation of canonical Wnt signaling pathway;GO:0051642//centrosome localization;GO:0060271//cilium assembly;GO:0042073//intraciliary transport;GO:0035735//intraciliary transport involved in cilium assembly;GO:0007224//smoothened signaling pathway;GO:0055007//cardiac muscle cell differentiation;GO:0061351//neural precursor cell proliferation;GO:2000785//regulation of autophagosome assembly;GO:0035845//photoreceptor cell outer segment organization;GO:0072659//protein localization to plasma membrane;GO:0060122//inner ear receptor cell stereocilium organization;GO:0036372//opsin transport;GO:0001736//establishment of planar polarity;GO:0090102//cochlea development","K16473//intraflagellar transport protein 20","XP_021572576.1//intraflagellar transport protein 20 homolog isoform X2 [Carlito syrichta];XP_017744399.1//PREDICTED: intraflagellar transport protein 20 homolog isoform X2 [Rhinopithecus bieti];NP_001254703.1//intraflagellar transport protein 20 homolog isoform 1 [Homo sapiens];XP_021068636.1//intraflagellar transport protein 20 homolog isoform X1 [Mus pahari];NP_777547.1//intraflagellar transport protein 20 homolog isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[8525,3676,23.05,25.84,0.164839319377224,0.0106864194213836,"*",0.00372292,"DGKZ","GO:0005634//nucleus;GO:0005622//intracellular;GO:0016607//nuclear speck;GO:0005886//plasma membrane;GO:0030027//lamellipodium;GO:0005737//cytoplasm","GO:0004143//diacylglycerol kinase activity;GO:0003951//NAD+ kinase activity;GO:0046872//metal ion binding;GO:0008022//protein C-terminus binding;GO:0001727//lipid kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity","GO:0031571//mitotic G1 DNA damage checkpoint;GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0016477//cell migration;GO:0045930//negative regulation of mitotic cell cycle;GO:0046486//glycerolipid metabolic process;GO:0030168//platelet activation;GO:0035556//intracellular signal transduction;GO:0046339//diacylglycerol metabolic process;GO:0046834//lipid phosphorylation","K00901//diacylglycerol kinase (ATP) [EC:2.7.1.107]","XP_016776258.1//PREDICTED: diacylglycerol kinase zeta isoform X15 [Pan troglodytes];NP_001186195.1//diacylglycerol kinase zeta isoform 5 [Homo sapiens];NP_003637.2//diacylglycerol kinase zeta isoform 2 [Homo sapiens];XP_016873945.1//PREDICTED: diacylglycerol kinase zeta isoform X2 [Homo sapiens];NP_963290.1//diacylglycerol kinase zeta isoform 1 [Homo sapiens];NP_001186196.1//diacylglycerol kinase zeta isoform 6 [Homo sapiens];NP_001186197.1//diacylglycerol kinase zeta isoform 7 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[7263,1111,25.59,28.68,0.164464876662458,0.226147989092149,"*",0.124598,"TST","GO:0005759//mitochondrial matrix;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0004792//thiosulfate sulfurtransferase activity;GO:0008097//5S rRNA binding","GO:0009440//cyanate catabolic process;GO:0035928//rRNA import into mitochondrion;GO:0051029//rRNA transport;GO:0030855//epithelial cell differentiation","K01011//thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]","XP_012642573.1//thiosulfate sulfurtransferase isoform X1 [Microcebus murinus];NP_003303.2//thiosulfate sulfurtransferase [Homo sapiens]","1//3;5"]
[8663,3100,127.95,143.29,0.163357782154206,{"v":3.08997666449511e-08,"d":"3.09E-08"},"*",{"v":4.15698e-09,"d":"4.16E-09"},"EIF3C","GO:0071541//eukaryotic translation initiation factor 3 complex, eIF3m;GO:0016282//eukaryotic 43S preinitiation complex;GO:0005829//cytosol;GO:0033290//eukaryotic 48S preinitiation complex;GO:0005852//eukaryotic translation initiation factor 3 complex","GO:0003743//translation initiation factor activity;GO:0003723//RNA binding;GO:0031369//translation initiation factor binding","GO:0006413//translational initiation;GO:0006446//regulation of translational initiation;GO:0045727//positive regulation of translation;GO:1902416//positive regulation of mRNA binding;GO:0001731//formation of translation preinitiation complex","K03252//translation initiation factor 3 subunit C","NP_001273407.1//eukaryotic translation initiation factor 3 subunit C isoform b [Homo sapiens];NP_003743.1//eukaryotic translation initiation factor 3 subunit C isoform a [Homo sapiens]","4;1//3;2//1"]
[4718,2490,49.75,55.69,0.162721766978638,0.00330456823893805,"*",0.001028566,"NDUFC2","GO:0005737//cytoplasm;GO:0035577//azurophil granule membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0070469//respiratory chain;GO:0005886//plasma membrane","GO:0008137//NADH dehydrogenase (ubiquinone) activity","GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0043312//neutrophil degranulation","K03968//NADH dehydrogenase (ubiquinone) 1 subunit C2","NP_001190983.1//NADH dehydrogenase [ubiquinone] 1 subunit C2 isoform 2 [Homo sapiens];NP_004540.1//NADH dehydrogenase [ubiquinone] 1 subunit C2 isoform 1 [Homo sapiens];NP_001190984.1//NADH dehydrogenase [ubiquinone] 1 subunit C2 isoform 3 [Homo sapiens]","1//3;5"]
[388789,551,64.24,71.87,0.161917793204006,0.176049102775442,"*",0.0917276,"SMIM26","NA","NA","NA","K07560//D-tyrosyl-tRNA(Tyr) deacylase [EC:3.1.-.-]","EAX10230.1//hCG21678 [Homo sapiens]","1//3"]
[823,3104,75.08,83.94,0.160929813055035,{"v":5.04744693812375e-05,"d":"5.05E-05"},"*",{"v":1.108138e-05,"d":"1.11E-05"},"CAPN1","GO:0070062//extracellular exosome;GO:0005925//focal adhesion;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005739//mitochondrion;GO:0005764//lysosome;GO:0005886//plasma membrane","GO:0004198//calcium-dependent cysteine-type endopeptidase activity;GO:0005509//calcium ion binding","GO:0060056//mammary gland involution;GO:0032801//receptor catabolic process;GO:0097264//self proteolysis;GO:0050790//regulation of catalytic activity","K01367//calpain-1 [EC:3.4.22.52]","XP_012666158.1//PREDICTED: calpain-1 catalytic subunit [Otolemur garnettii]","1//3;3//A2MP1"]
[10461,3632,0.68,0.76,0.160464672193246,0.732822325388601,"*",0.619784,"MERTK","GO:0005615//extracellular space;GO:0016028//rhabdomere;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0001750//photoreceptor outer segment;GO:0005737//cytoplasm","GO:0005524//ATP binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity","GO:0060041//retina development in camera-type eye;GO:0060068//vagina development;GO:0051250//negative regulation of lymphocyte activation;GO:0043491//protein kinase B signaling;GO:0030168//platelet activation;GO:0007166//cell surface receptor signaling pathway;GO:0007283//spermatogenesis;GO:0050766//positive regulation of phagocytosis;GO:0001818//negative regulation of cytokine production;GO:0006909//phagocytosis;GO:0034446//substrate adhesion-dependent cell spreading;GO:0050900//leukocyte migration;GO:0007267//cell-cell signaling;GO:0001779//natural killer cell differentiation;GO:0006468//protein phosphorylation;GO:0043277//apoptotic cell clearance;GO:0032940//secretion by cell;GO:0097350//neutrophil clearance;GO:2000107//negative regulation of leukocyte apoptotic process","K05117//c-mer proto-oncogene tyrosine kinase [EC:2.7.10.1]","NP_006334.2//tyrosine-protein kinase Mer precursor [Homo sapiens]","2//1"]
[10591,712,47.56,53.12,0.159506431601269,0.14675283099814,"*",0.074093,"DNPH1","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0070694//deoxyribonucleoside 5'-monophosphate N-glycosidase activity;GO:0042802//identical protein binding;GO:0050144//nucleoside deoxyribosyltransferase activity;GO:0042803//protein homodimerization activity","GO:0009159//deoxyribonucleoside monophosphate catabolic process;GO:0009116//nucleoside metabolic process;GO:0008283//cell proliferation;GO:0006195//purine nucleotide catabolic process;GO:0030307//positive regulation of cell growth;GO:0009117//nucleotide metabolic process;GO:0030855//epithelial cell differentiation","NA","EAX04165.1//chromosome 6 open reading frame 108, isoform CRA_a [Homo sapiens];NP_006434.1//2'-deoxynucleoside 5'-phosphate N-hydrolase 1 isoform 1 [Homo sapiens]","1//3;2//1"]
[63908,3767,1.63,1.82,0.159066485967619,0.631245661948376,"*",0.4746,"NAPB","GO:0005774//vacuolar membrane;GO:0070062//extracellular exosome;GO:0005622//intracellular;GO:0043209//myelin sheath;GO:0031201//SNARE complex;GO:0045202//synapse;GO:0070044//synaptobrevin 2-SNAP-25-syntaxin-1a complex","GO:0005483//soluble NSF attachment protein activity;GO:0019905//syntaxin binding","GO:0006886//intracellular protein transport;GO:0048488//synaptic vesicle endocytosis;GO:0061025//membrane fusion;GO:0035249//synaptic transmission, glutamatergic;GO:0010807//regulation of synaptic vesicle priming;GO:0035494//SNARE complex disassembly","K15296//alpha-soluble NSF attachment protein;K05858//phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]","NP_062606.1//beta-soluble NSF attachment protein [Mus musculus];NP_001269949.1//beta-soluble NSF attachment protein isoform c [Homo sapiens];NP_001269947.1//beta-soluble NSF attachment protein isoform a [Homo sapiens];XP_012666003.1//PREDICTED: beta-soluble NSF attachment protein isoform X3 [Otolemur garnettii]","1//3;2//1"]
[6227,418,235.38,262.71,0.158479376146328,0.0181535911103611,"*",0.00673458,"RPS21","GO:0005840//ribosome;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0022627//cytosolic small ribosomal subunit;GO:0015935//small ribosomal subunit","GO:0043022//ribosome binding;GO:0003723//RNA binding;GO:0047485//protein N-terminus binding;GO:0003735//structural constituent of ribosome","GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0000461//endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000447//endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006364//rRNA processing;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006413//translational initiation;GO:0006412//translation;GO:0019083//viral transcription","K02971//small subunit ribosomal protein S21e","XP_011964398.1//PREDICTED: 40S ribosomal protein S21 isoform X3 [Ovis aries musimon]","3//A2MP1"]
[79701,4403,9.44,10.53,0.157646671663876,0.119090887795993,"*",0.0573014,"OGFOD3","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0016021//integral component of membrane","GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0005506//iron ion binding;GO:0031418//L-ascorbic acid binding;GO:0051213//dioxygenase activity","NA","K22069//LYR motif-containing protein 4;K12581//CCR4-NOT transcription complex subunit 7/8","NP_078924.1//2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3 isoform 1 [Homo sapiens];NP_787098.3//2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3 isoform 2 [Homo sapiens]","4;2//1"]
[51082,1181,60.05,66.97,0.157350722119159,0.148631859315119,"*",0.075265,"POLR1D","GO:0005666//DNA-directed RNA polymerase III complex;GO:0005736//DNA-directed RNA polymerase I complex","GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0003677//DNA binding;GO:0046983//protein dimerization activity","GO:0006360//transcription from RNA polymerase I promoter;GO:0006351//transcription, DNA-templated;GO:0006383//transcription from RNA polymerase III promoter","K03020//DNA-directed RNA polymerases I and III subunit RPAC2","NP_057056.1//DNA-directed RNA polymerases I and III subunit RPAC2 isoform 1 [Homo sapiens];XP_008969889.1//PREDICTED: uncharacterized protein LOC100990631 [Pan paniscus];NP_689918.1//DNA-directed RNA polymerases I and III subunit RPAC2 isoform 2 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[284361,2126,133.69,149.06,0.15700160876454,{"v":1.0563796244373e-05,"d":"1.06E-05"},"*",{"v":2.05668E-6,"d":"2.06E-06"},"EMC10","GO:0072546//ER membrane protein complex;GO:0016021//integral component of membrane;GO:0005576//extracellular region","NA","NA","K19475//WAS/WASL-interacting protein;K11448//lysine-specific demethylase 6B [EC:1.14.11.-]","NP_996261.1//ER membrane protein complex subunit 10 isoform 2 precursor [Homo sapiens]","3//A2MP1;5"]
[83877,3359,16.72,18.63,0.156052826860755,0.10638379088017,"*",0.0502416,"TM2D2","GO:0016021//integral component of membrane","NA","NA","K15696//RING finger protein 113B;K17985//activating molecule in BECN1-regulated autophagy protein 1;K09488//TNF receptor-associated protein 1","XP_002757017.2//PREDICTED: TM2 domain-containing protein 2 [Callithrix jacchus];NP_114146.3//TM2 domain-containing protein 2 isoform b [Homo sapiens]","1//3;3//A2MP1;2//1"]
[100287932,1239,99.95,111.33,0.155563934786692,0.005749268,"*",0.001877312,"TIMM23","GO:0005744//mitochondrial inner membrane presequence translocase complex;GO:0016021//integral component of membrane;GO:0005758//mitochondrial intermembrane space;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0031305//integral component of mitochondrial inner membrane","GO:0015266//protein channel activity;GO:0015450//P-P-bond-hydrolysis-driven protein transmembrane transporter activity","GO:0006886//intracellular protein transport;GO:0006626//protein targeting to mitochondrion;GO:0030150//protein import into mitochondrial matrix","K17794//mitochondrial import inner membrane translocase subunit TIM23","NP_006318.1//mitochondrial import inner membrane translocase subunit Tim23 [Homo sapiens]","3//A2MP1"]
[3030,3048,67.09,74.7,0.155010499324512,0.000222804521335712,"*",{"v":5.47178E-5,"d":"5.47E-05"},"HADHA","GO:0031012//extracellular matrix;GO:0042645//mitochondrial nucleoid;GO:0016507//mitochondrial fatty acid beta-oxidation multienzyme complex;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0051287//NAD binding;GO:0000062//fatty-acyl-CoA binding;GO:0003988//acetyl-CoA C-acyltransferase activity;GO:0016509//long-chain-3-hydroxyacyl-CoA dehydrogenase activity;GO:0003985//acetyl-CoA C-acetyltransferase activity;GO:0003857//3-hydroxyacyl-CoA dehydrogenase activity;GO:0016508//long-chain-enoyl-CoA hydratase activity;GO:0004300//enoyl-CoA hydratase activity;GO:0032403//protein complex binding","GO:0042493//response to drug;GO:0006635//fatty acid beta-oxidation;GO:0032868//response to insulin;GO:0035965//cardiolipin acyl-chain remodeling","K07515//enoyl-CoA hydratase / long-chain 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.211]","NP_000173.2//trifunctional enzyme subunit alpha, mitochondrial precursor [Homo sapiens]",4]
[10695,1787,27.49,30.6,0.154624746067061,0.0362845182965592,"*",0.01472142,"CNPY3","GO:0005788//endoplasmic reticulum lumen","GO:0005102//receptor binding","GO:0002224//toll-like receptor signaling pathway;GO:0045087//innate immune response","NA","NP_001305771.1//protein canopy homolog 3 isoform 3 precursor [Homo sapiens];NP_001305774.1//protein canopy homolog 3 isoform 2 [Homo sapiens];NP_001305776.1//protein canopy homolog 3 isoform 5 precursor [Homo sapiens];NP_001305777.1//protein canopy homolog 3 isoform 6 precursor [Homo sapiens];NP_006577.2//protein canopy homolog 3 isoform 1 precursor [Homo sapiens]","1//3;4"]
[27351,3804,21.71,24.16,0.154260728709935,0.0282851163351455,"*",0.01107394,"DESI1","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0008233//peptidase activity;GO:0042802//identical protein binding","NA","K11447//histone demethylase [EC:1.14.11.-];K17985//activating molecule in BECN1-regulated autophagy protein 1","XP_007974111.1//PREDICTED: desumoylating isopeptidase 1 [Chlorocebus sabaeus]","2//1"]
[374,1290,42.66,47.45,0.1535241215679,0.0883558204003813,"*",0.0406158,"AREG","GO:0005634//nucleus;GO:0005615//extracellular space;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0005737//cytoplasm;GO:0000139//Golgi membrane;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0012507//ER to Golgi transport vesicle membrane","GO:0008083//growth factor activity;GO:0005125//cytokine activity;GO:0005154//epidermal growth factor receptor binding","GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0048208//COPII vesicle coating;GO:0060598//dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis;GO:0032355//response to estradiol;GO:0008283//cell proliferation;GO:0045668//negative regulation of osteoblast differentiation;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0031175//neuron projection development;GO:0051384//response to glucocorticoid;GO:0007186//G-protein coupled receptor signaling pathway;GO:0043434//response to peptide hormone;GO:0051591//response to cAMP;GO:0007267//cell-cell signaling;GO:0060744//mammary gland branching involved in thelarche;GO:0042542//response to hydrogen peroxide;GO:0045740//positive regulation of DNA replication;GO:0060749//mammary gland alveolus development;GO:0060750//epithelial cell proliferation involved in mammary gland duct elongation;GO:0014009//glial cell proliferation;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0008284//positive regulation of cell proliferation","K09782//amphiregulin","NP_001648.1//amphiregulin preproprotein [Homo sapiens]","3//A2MP1"]
[355,3942,2.94,3.27,0.153474480661718,0.473777420564183,"*",0.322782,"FAS","GO:0016020//membrane;GO:0031264//death-inducing signaling complex;GO:0009986//cell surface;GO:0031265//CD95 death-inducing signaling complex;GO:0005829//cytosol","GO:0004872//receptor activity;GO:0042802//identical protein binding;GO:0004888//transmembrane signaling receptor activity;GO:0019900//kinase binding;GO:0005516//calmodulin binding","GO:0097296//activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway;GO:0006955//immune response;GO:0006924//activation-induced cell death of T cells;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006915//apoptotic process","K04390//tumor necrosis factor receptor superfamily member 6","NP_690611.1//tumor necrosis factor receptor superfamily member 6 isoform 3 precursor [Homo sapiens];NP_001307548.1//tumor necrosis factor receptor superfamily member 6 isoform 4 precursor [Homo sapiens];NP_690610.1//tumor necrosis factor receptor superfamily member 6 isoform 2 precursor [Homo sapiens];NP_000034.1//tumor necrosis factor receptor superfamily member 6 isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1;5"]
[9114,1688,62.74,69.75,0.152807687760309,0.0125802700035199,"*",0.00447484,"ATP6V0D1","GO:0016020//membrane;GO:0010008//endosome membrane;GO:0033179//proton-transporting V-type ATPase, V0 domain;GO:0005765//lysosomal membrane;GO:0070062//extracellular exosome;GO:0016324//apical plasma membrane;GO:0008021//synaptic vesicle;GO:0005813//centrosome;GO:0030670//phagocytic vesicle membrane;GO:0043005//neuron projection;GO:0043234//protein complex;GO:0005623//cell;GO:0043679//axon terminus;GO:0005769//early endosome;GO:0016471//vacuolar proton-transporting V-type ATPase complex","GO:0015078//hydrogen ion transmembrane transporter activity;GO:0008553//hydrogen-exporting ATPase activity, phosphorylative mechanism;GO:0032403//protein complex binding;GO:0046961//proton-transporting ATPase activity, rotational mechanism","GO:0016241//regulation of macroautophagy;GO:0006879//cellular iron ion homeostasis;GO:0008286//insulin receptor signaling pathway;GO:0034220//ion transmembrane transport;GO:0036295//cellular response to increased oxygen levels;GO:0090383//phagosome acidification;GO:0007420//brain development;GO:0007034//vacuolar transport;GO:0007035//vacuolar acidification;GO:0015991//ATP hydrolysis coupled proton transport;GO:0060271//cilium assembly;GO:0036498//IRE1-mediated unfolded protein response;GO:0033572//transferrin transport;GO:0015992//proton transport","K02146//V-type H+-transporting ATPase subunit d","NP_004682.2//V-type proton ATPase subunit d 1 [Homo sapiens]",4]
[6230,514,449.03,498.95,0.152083414074014,0.000225205332620321,"*",{"v":5.53638E-5,"d":"5.54E-05"},"RPS25","NA","NA","NA","K02975//small subunit ribosomal protein S25e","XP_012363578.1//PREDICTED: LOW QUALITY PROTEIN: 40S ribosomal protein S25-like [Nomascus leucogenys]","2//1"]
[25759,2509,0.54,0.6,0.15200309344505,0.819513260700389,"*",0.738352,"SHC2","GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0030971//receptor tyrosine kinase binding","GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0000165//MAPK cascade;GO:0000187//activation of MAPK activity;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0007265//Ras protein signal transduction","K17447//SHC-transforming protein 2","NP_036567.2//SHC-transforming protein 2 [Homo sapiens]","2//1"]
[5339,14712,51.23,56.9,0.151439760739381,{"v":9.46245887767796e-12,"d":"9.46E-12"},"*",{"v":8.57154e-13,"d":"8.57E-13"},"PLEC","GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0005925//focal adhesion;GO:0005903//brush border;GO:0045111//intermediate filament cytoskeleton;GO:0043034//costamere;GO:0016528//sarcoplasm;GO:0005829//cytosol;GO:0030056//hemidesmosome;GO:0042383//sarcolemma;GO:0005886//plasma membrane","GO:0003779//actin binding;GO:0003723//RNA binding;GO:0008307//structural constituent of muscle;GO:0030506//ankyrin binding;GO:0045296//cadherin binding","GO:0031581//hemidesmosome assembly","K10388//plectin","NP_958784.1//plectin isoform 1b [Homo sapiens];NP_958781.1//plectin isoform 1e [Homo sapiens];NP_958780.1//plectin isoform 1f [Homo sapiens];NP_958783.1//plectin isoform 1d [Homo sapiens];NP_958785.1//plectin isoform 1g [Homo sapiens];NP_000436.2//plectin isoform 1c [Homo sapiens];NP_958786.1//plectin isoform 1a [Homo sapiens];NP_958782.1//plectin isoform 1 [Homo sapiens]","4;3//A2MP1;2//1"]
[283951,994,15.75,17.48,0.150353356225957,0.432213649262202,"*",0.28605,"C16orf91","GO:0016021//integral component of membrane","NA","NA","NA","AAK61280.1//unknown [Homo sapiens]","1//3"]
[57176,3580,8.67,9.62,0.150004900548207,0.446109982982702,"*",0.298682,"VARS2","GO:0005739//mitochondrion","GO:0004832//valine-tRNA ligase activity;GO:0005524//ATP binding;GO:0002161//aminoacyl-tRNA editing activity;GO:0004812//aminoacyl-tRNA ligase activity","GO:0006418//tRNA aminoacylation for protein translation;GO:0006438//valyl-tRNA aminoacylation","K01873//valyl-tRNA synthetase [EC:6.1.1.9]","NP_065175.4//valine--tRNA ligase, mitochondrial isoform 2 precursor [Homo sapiens];NP_001161206.1//valine--tRNA ligase, mitochondrial isoform 1 [Homo sapiens]","1//3;2//1;5"]
[51329,1343,49.25,54.6,0.148777226576114,0.074970085002798,"*",0.0335474,"ARL6IP4","NA","NA","NA","K13170//splicing factor, arginine/serine-rich 18;K13114//pinin;K13165//splicing factor, arginine/serine-rich 12;K17498//transcription factor SPN1","XP_018893876.1//PREDICTED: ADP-ribosylation factor-like protein 6-interacting protein 4 isoform X3 [Gorilla gorilla gorilla];XP_009424768.1//PREDICTED: ADP-ribosylation factor-like protein 6-interacting protein 4 isoform X1 [Pan troglodytes];XP_009424771.1//PREDICTED: ADP-ribosylation factor-like protein 6-interacting protein 4 isoform X4 [Pan troglodytes];XP_018893877.1//PREDICTED: ADP-ribosylation factor-like protein 6-interacting protein 4 isoform X4 [Gorilla gorilla gorilla];XP_009424769.1//PREDICTED: ADP-ribosylation factor-like protein 6-interacting protein 4 isoform X2 [Pan troglodytes]","1//3;3//A2MP1;2//1"]
[252839,1603,55.99,62.06,0.148494516815727,0.0262992657696031,"*",0.01020426,"TMEM9","GO:0005765//lysosomal membrane;GO:0005770//late endosome;GO:0031902//late endosome membrane;GO:0016021//integral component of membrane;GO:0005764//lysosome","NA","GO:0006810//transport","K09067//achaete-scute complex protein;K06013//STE24 endopeptidase [EC:3.4.24.84]","XP_012357475.1//PREDICTED: transmembrane protein 9 isoform X1 [Nomascus leucogenys];XP_003264578.1//PREDICTED: transmembrane protein 9 isoform X2 [Nomascus leucogenys]","4;1//3"]
[102724231,772,0.74,0.82,0.148098638989134,0.858465450774374,"*",0.787688,"LINC00694","NA","NA","NA","K10798//poly [ADP-ribose] polymerase [EC:2.4.2.30];K16882//protein piccolo","NP_001338409.1//putative uncharacterized protein LINC00694 [Homo sapiens]","1//3"]
[3835,2161,48.88,54.14,0.147450602396234,0.0164700462380301,"*",0.0060296,"KIF22","GO:0072686//mitotic spindle;GO:0005634//nucleus;GO:0005874//microtubule;GO:0005829//cytosol;GO:0000785//chromatin;GO:0016607//nuclear speck;GO:0000776//kinetochore;GO:0005871//kinesin complex","GO:0003677//DNA binding;GO:0005524//ATP binding;GO:0003777//microtubule motor activity;GO:0008017//microtubule binding;GO:0016887//ATPase activity","GO:0000278//mitotic cell cycle;GO:0007018//microtubule-based movement;GO:0006281//DNA repair;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0007080//mitotic metaphase plate congression;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0007062//sister chromatid cohesion;GO:0051310//metaphase plate congression","K10403//kinesin family member 22","NP_015556.1//kinesin-like protein KIF22 isoform 1 [Homo sapiens]","1//3;2//1"]
[5031,2441,7.66,8.48,0.146719872638242,0.457794720416125,"*",0.30854,"P2RY6","GO:0016323//basolateral plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016324//apical plasma membrane;GO:0005886//plasma membrane","GO:0045028//G-protein coupled purinergic nucleotide receptor activity;GO:0045029//UDP-activated nucleotide receptor activity;GO:0004930//G-protein coupled receptor activity","GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0030321//transepithelial chloride transport;GO:0071407//cellular response to organic cyclic compound;GO:0071380//cellular response to prostaglandin E stimulus;GO:0014911//positive regulation of smooth muscle cell migration","K04272//purinergic receptor P2Y, G protein-coupled, 6","XP_012312354.2//P2Y purinoceptor 6 isoform X1 [Aotus nancymaae];XP_017833296.1//PREDICTED: P2Y purinoceptor 6 isoform X1 [Callithrix jacchus];NP_001264137.1//P2Y purinoceptor 6 isoform 2 [Homo sapiens]","1//3;2//1"]
[28989,1461,35.83,39.65,0.146152822380605,0.098502474879227,"*",0.0459522,"NTMT1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0008168//methyltransferase activity;GO:0071885//N-terminal protein N-methyltransferase activity;GO:0008276//protein methyltransferase activity;GO:0042054//histone methyltransferase activity","GO:0016571//histone methylation;GO:0007059//chromosome segregation;GO:0018016//N-terminal peptidyl-proline dimethylation;GO:0035570//N-terminal peptidyl-serine methylation;GO:0018011//N-terminal peptidyl-alanine methylation;GO:0018013//N-terminal peptidyl-glycine methylation;GO:0035573//N-terminal peptidyl-serine trimethylation;GO:0007051//spindle organization;GO:0006480//N-terminal protein amino acid methylation;GO:0035568//N-terminal peptidyl-proline methylation;GO:0035572//N-terminal peptidyl-serine dimethylation;GO:0018012//N-terminal peptidyl-alanine trimethylation","K16219//protein N-terminal methyltransferase [EC:2.1.1.244]","NP_054783.2//N-terminal Xaa-Pro-Lys N-methyltransferase 1 isoform a [Homo sapiens];EAW87894.1//chromosome 9 open reading frame 32, isoform CRA_b, partial [Homo sapiens]","1//3;3//A2MP1"]
[1196,2140,13.94,15.42,0.145572204046611,0.242438714342984,"*",0.1362902,"CLK2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0016607//nuclear speck","GO:0004713//protein tyrosine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0042802//identical protein binding","GO:0043484//regulation of RNA splicing;GO:0010212//response to ionizing radiation;GO:0006468//protein phosphorylation;GO:0032526//response to retinoic acid;GO:0045721//negative regulation of gluconeogenesis;GO:0046777//protein autophosphorylation","K08823//CDC-like kinase [EC:2.7.12.1]","ERE92257.1//dual specificity protein kinase CLK2 [Cricetulus griseus];EDL15234.1//CDC-like kinase 2, isoform CRA_b, partial [Mus musculus];XP_017375283.1//PREDICTED: dual specificity protein kinase CLK2 isoform X1 [Cebus capucinus imitator]","1//3;3//A2MP1"]
[284254,1914,0.38,0.42,0.144389909335175,1.01995750333162,"*",0.996588,"DYNAP","GO:0016021//integral component of membrane","NA","NA","K10955//mucin-2","XP_006143512.2//PREDICTED: LOW QUALITY PROTEIN: dynactin-associated protein [Tupaia chinensis];XP_017496475.1//PREDICTED: LOW QUALITY PROTEIN: mucin-22-like [Manis javanica]","1//3;2//1"]
[81853,1004,77.92,86.09,0.143851990070903,0.0642238945891783,"*",0.0280874,"TMEM14B","GO:0016021//integral component of membrane","NA","NA","K22069//LYR motif-containing protein 4;K12581//CCR4-NOT transcription complex subunit 7/8;K04487//cysteine desulfurase [EC:2.8.1.7]","NP_001273417.1//transmembrane protein 14B isoform d [Homo sapiens];NP_001121183.1//transmembrane protein 14B isoform b [Homo sapiens];EAW55278.1//transmembrane protein 14B, isoform CRA_c, partial [Homo sapiens];NP_001273418.1//transmembrane protein 14B isoform e [Homo sapiens];NP_001273413.1//transmembrane protein 14B isoform c [Homo sapiens]","1//3;4;2//1"]
[28973,1536,49.79,55,0.143575603233335,0.0551029596498906,"*",0.0236466,"MRPS18B","GO:0005840//ribosome;GO:0005654//nucleoplasm;GO:0005763//mitochondrial small ribosomal subunit;GO:0005743//mitochondrial inner membrane;GO:0030054//cell junction;GO:0005739//mitochondrion","GO:0003735//structural constituent of ribosome","GO:0032543//mitochondrial translation;GO:0006412//translation;GO:0070126//mitochondrial translational termination;GO:0070125//mitochondrial translational elongation","K16174//small subunit ribosomal protein S18b, mitochondrial","XP_004065427.1//PREDICTED: LOW QUALITY PROTEIN: 28S ribosomal protein S18b, mitochondrial [Gorilla gorilla gorilla]","3//A2MP1"]
[114790,3629,10.06,11.11,0.143228511583565,0.213944146601942,"*",0.1158786,"STK11IP","GO:0005765//lysosomal membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0035578//azurophil granule lumen;GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0019901//protein kinase binding","GO:0008104//protein localization;GO:0043312//neutrophil degranulation","K19475//WAS/WASL-interacting protein;K02184//formin 2;K05748//WAS protein family, member 2","Q8N1F8.3//RecName: Full=Serine/threonine-protein kinase 11-interacting protein; AltName: Full=LKB1-interacting protein 1","3//A2MP1"]
[5552,1529,46.13,50.94,0.143093667208539,0.0967629401856585,"*",0.0450256,"SRGN","GO:0031093//platelet alpha granule lumen;GO:0005615//extracellular space;GO:0005794//Golgi apparatus;GO:0042588//zymogen granule;GO:0005576//extracellular region;GO:0042629//mast cell granule;GO:0000139//Golgi membrane","GO:0005518//collagen binding","GO:0033373//maintenance of protease location in mast cell secretory granule;GO:0030502//negative regulation of bone mineralization;GO:0033382//maintenance of granzyme B location in T cell secretory granule;GO:0033368//protease localization to mast cell secretory granule;GO:0008626//granzyme-mediated apoptotic signaling pathway;GO:0033364//mast cell secretory granule organization;GO:0002576//platelet degranulation;GO:0016485//protein processing;GO:0031214//biomineral tissue development;GO:0050710//negative regulation of cytokine secretion;GO:0033371//T cell secretory granule organization","K06849//proteoglycan peptide core protein","NP_002718.2//serglycin isoform 1 precursor [Homo sapiens];NP_001307983.1//serglycin isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[9266,4623,22.02,24.3,0.142141844928774,0.02378303008,"*",0.00911926,"CYTH2","NA","GO:0005086//ARF guanyl-nucleotide exchange factor activity","GO:0032012//regulation of ARF protein signal transduction","K18441//cytohesin","XP_003269786.1//PREDICTED: cytohesin-2 isoform X1 [Nomascus leucogenys];XP_003269785.1//PREDICTED: cytohesin-2 isoform X2 [Nomascus leucogenys]","6;5"]
[54494,2019,3.5,3.86,0.141245925435751,0.624706852459016,"*",0.50097,"C11orf71","NA","NA","NA","NA","NP_001258491.1//uncharacterized protein C11orf71 isoform 1 [Homo sapiens];NP_061894.2//uncharacterized protein C11orf71 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[57116,1381,1.46,1.61,0.1410923192346,1.02150639516647,"*",0.994904,"ZNF695","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","XP_021565913.1//zinc finger protein 208-like [Carlito syrichta];NP_001191150.1//zinc finger protein 695 isoform 2 [Homo sapiens]","4;1//3"]
[54543,796,71.4,78.72,0.140806146422778,0.122574295314522,"*",0.0592844,"TOMM7","GO:0005742//mitochondrial outer membrane translocase complex;GO:0031307//integral component of mitochondrial outer membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane","GO:0008320//protein transmembrane transporter activity","GO:0098779//positive regulation of mitophagy in response to mitochondrial depolarization;GO:0006626//protein targeting to mitochondrion;GO:0045040//protein import into mitochondrial outer membrane;GO:0031647//regulation of protein stability;GO:1903955//positive regulation of protein targeting to mitochondrion;GO:0030150//protein import into mitochondrial matrix;GO:0016236//macroautophagy","K17771//mitochondrial import receptor subunit TOM7","XP_012925743.2//mitochondrial import receptor subunit TOM7 homolog [Heterocephalus glaber]","3//A2MP1"]
[10607,2618,20.36,22.43,0.139692059010577,0.130422581665607,"*",0.0642152,"TBL3","GO:0034388//Pwp2p-containing subcomplex of 90S preribosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0032040//small-subunit processome;GO:0005730//nucleolus","GO:0030515//snoRNA binding;GO:0003723//RNA binding","GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006364//rRNA processing","K14555//U3 small nucleolar RNA-associated protein 13","BAD92410.1//transducin beta-like 3 variant, partial [Homo sapiens]","2//1"]
[84836,2130,26.53,29.22,0.139331502574802,0.0687922747480483,"*",0.0303394,"ABHD14B","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005829//cytosol","GO:0016787//hydrolase activity","GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0050427//3'-phosphoadenosine 5'-phosphosulfate metabolic process","K13706//abhydrolase domain-containing protein 14","XP_004034308.1//PREDICTED: protein ABHD14B isoform X1 [Gorilla gorilla gorilla];AAH50650.1//ABHD14B protein, partial [Homo sapiens];NP_001241682.1//protein ABHD14B isoform 3 [Homo sapiens]","1//3;2//1"]
[116840,3529,21.98,24.2,0.138815661212726,0.0873556326419214,"*",0.040074,"CNTROB","GO:0005814//centriole;GO:0005829//cytosol;GO:0005813//centrosome","GO:0019904//protein domain specific binding","GO:1902410//mitotic cytokinetic process;GO:0051299//centrosome separation;GO:0007099//centriole replication","K16468//centrobin","BAF85765.1//unnamed protein product [Homo sapiens];NP_001340131.1//centrobin isoform delta [Homo sapiens];NP_444279.2//centrobin isoform alpha [Homo sapiens];NP_001340134.1//centrobin isoform epsilon [Homo sapiens];NP_001032221.1//centrobin isoform beta [Homo sapiens];NP_001317053.1//centrobin isoform gamma [Homo sapiens]","6;4;1//3;2//1"]
[63905,1279,96.69,106.44,0.138601821241519,0.0276759802888318,"*",0.01079734,"MANBAL","GO:0016021//integral component of membrane","NA","NA","K09291//nucleoprotein TPR","XP_011784469.1//PREDICTED: protein MANBAL isoform X1 [Colobus angolensis palliatus]","1//3;3//A2MP1"]
[340562,2167,0.3,0.33,0.137503523749935,0.877313447874357,"*",0.811298,"SATL1","GO:0005829//cytosol","GO:0019809//spermidine binding;GO:0004145//diamine N-acetyltransferase activity","GO:0032918//spermidine acetylation;GO:0046208//spermine catabolic process","K19017//interphotoreceptor matrix proteoglycan 2","NP_001012998.2//spermidine/spermine N(1)-acetyltransferase-like protein 1 [Homo sapiens]","2//1"]
[8233,1512,5.42,5.96,0.13701947910829,0.640324101613571,"*",0.484432,"ZRSR2","GO:0005654//nucleoplasm;GO:0089701//U2AF;GO:0005689//U12-type spliceosomal complex","GO:0046872//metal ion binding;GO:0030628//pre-mRNA 3'-splice site binding","GO:0000398//mRNA splicing, via spliceosome;GO:0000245//spliceosomal complex assembly;GO:0008380//RNA splicing","K13169//splicing factor, arginine/serine-rich 17","NP_005080.1//U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2 [Homo sapiens]","3//A2MP1"]
[57128,1193,32.49,35.71,0.136332390256582,0.0158206539907232,"*",0.00576512,"LYRM4","GO:0005759//mitochondrial matrix;GO:0016604//nuclear body;GO:0005739//mitochondrion","NA","GO:0044281//small molecule metabolic process","K22069//LYR motif-containing protein 4","EAW55178.1//chromosome 6 open reading frame 149, isoform CRA_c, partial [Homo sapiens];EAW55176.1//chromosome 6 open reading frame 149, isoform CRA_a, partial [Homo sapiens]","1//3;2//1;5"]
[1291,4246,9.24,10.15,0.135514970656481,0.221507842696629,"*",0.120946,"COL6A1","NA","NA","NA","K19720//collagen, type III, alpha","ETE70123.1//Collagen alpha-2(VI) chain, partial [Ophiophagus hannah]","2//1"]
[22818,1893,160.12,175.74,0.134289078212984,1.11678571767241E-4,"*",{"v":2.59516e-05,"d":"2.60E-05"},"COPZ1","GO:0030117//membrane coat;GO:0030126//COPI vesicle coat;GO:0030133//transport vesicle;GO:0005829//cytosol;GO:0005789//endoplasmic reticulum membrane;GO:0000139//Golgi membrane","NA","GO:0006886//intracellular protein transport;GO:1901998//toxin transport;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0016192//vesicle-mediated transport","K20472//coatomer subunit zeta","NP_001258665.1//coatomer subunit zeta-1 isoform 4 [Homo sapiens];NP_001258664.1//coatomer subunit zeta-1 isoform 3 [Homo sapiens];XP_013204176.1//PREDICTED: coatomer subunit zeta-1 [Microtus ochrogaster];NP_001258663.1//coatomer subunit zeta-1 isoform 2 [Homo sapiens]","1//3;2//1"]
[1512,1514,9.36,10.27,0.133855746734791,0.463907400369686,"*",0.314228,"CTSH","GO:1904724//tertiary granule lumen;GO:0034774//secretory granule lumen;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005764//lysosome;GO:0097486//multivesicular body lumen;GO:0097208//alveolar lamellar body;GO:0005829//cytosol;GO:0005576//extracellular region;GO:1904813//ficolin-1-rich granule lumen;GO:0036464//cytoplasmic ribonucleoprotein granule","GO:0004252//serine-type endopeptidase activity;GO:0004175//endopeptidase activity;GO:0030108//HLA-A specific activating MHC class I receptor activity;GO:0008233//peptidase activity;GO:0008656//cysteine-type endopeptidase activator activity involved in apoptotic process;GO:0070324//thyroid hormone binding;GO:0004177//aminopeptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0004197//cysteine-type endopeptidase activity","GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0030335//positive regulation of cell migration;GO:0010813//neuropeptide catabolic process;GO:0070371//ERK1 and ERK2 cascade;GO:0044267//cellular protein metabolic process;GO:0010634//positive regulation of epithelial cell migration;GO:0043312//neutrophil degranulation;GO:0033619//membrane protein proteolysis;GO:0002764//immune response-regulating signaling pathway;GO:0045766//positive regulation of angiogenesis;GO:0031648//protein destabilization;GO:0010815//bradykinin catabolic process;GO:0001656//metanephros development;GO:0001913//T cell mediated cytotoxicity;GO:0019882//antigen processing and presentation;GO:0060448//dichotomous subdivision of terminal units involved in lung branching;GO:0043066//negative regulation of apoptotic process;GO:0032526//response to retinoic acid;GO:0010628//positive regulation of gene expression;GO:0002250//adaptive immune response;GO:2001235//positive regulation of apoptotic signaling pathway;GO:0006508//proteolysis;GO:0006955//immune response;GO:0031638//zymogen activation;GO:0010952//positive regulation of peptidase activity;GO:0097067//cellular response to thyroid hormone stimulus;GO:0043129//surfactant homeostasis;GO:0008284//positive regulation of cell proliferation","K01366//cathepsin H [EC:3.4.22.16]","XP_018866236.1//PREDICTED: pro-cathepsin H isoform X3 [Gorilla gorilla gorilla];NP_004381.2//pro-cathepsin H isoform a preproprotein [Homo sapiens]","1//3;4"]
[9127,2759,0.62,0.68,0.133266530863464,0.837333357762777,"*",0.761012,"P2RX6","GO:0098794//postsynapse;GO:0005887//integral component of plasma membrane;GO:0030054//cell junction;GO:0005639//integral component of nuclear inner membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0004931//extracellularly ATP-gated cation channel activity;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0004888//transmembrane signaling receptor activity;GO:0001614//purinergic nucleotide receptor activity;GO:0015267//channel activity","GO:0006810//transport;GO:0033198//response to ATP;GO:0007165//signal transduction;GO:0007596//blood coagulation;GO:0006936//muscle contraction;GO:0051260//protein homooligomerization","K05221//P2X purinoceptor 6","NP_001336805.1//P2X purinoceptor 6 isoform 4 [Homo sapiens];NP_005437.2//P2X purinoceptor 6 isoform 1 [Homo sapiens];NP_001153026.1//P2X purinoceptor 6 isoform 2 [Homo sapiens];NP_001336803.1//P2X purinoceptor 6 isoform 3 [Homo sapiens]","4;1//3"]
[90378,2396,40.78,44.71,0.132735770526045,0.0417874527407407,"*",0.01730462,"SAMD1","GO:0005576//extracellular region;GO:0005737//cytoplasm","NA","NA","K16628//collagen, type VII, alpha","NP_612361.1//atherin [Homo sapiens]","2//1"]
[8318,1981,23.12,25.34,0.132275126640131,0.167898122346098,"*",0.0867344,"CDC45","GO:0031261//DNA replication preinitiation complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031298//replication fork protection complex;GO:0005656//nuclear pre-replicative complex;GO:0005813//centrosome;GO:0005737//cytoplasm","GO:0003688//DNA replication origin binding;GO:0003697//single-stranded DNA binding;GO:0003682//chromatin binding;GO:0043138//3'-5' DNA helicase activity","GO:1900087//positive regulation of G1/S transition of mitotic cell cycle;GO:1902977//mitotic DNA replication preinitiation complex assembly;GO:0000727//double-strand break repair via break-induced replication;GO:0006260//DNA replication;GO:0006270//DNA replication initiation;GO:0000076//DNA replication checkpoint;GO:0031938//regulation of chromatin silencing at telomere;GO:0006267//pre-replicative complex assembly involved in nuclear cell cycle DNA replication;GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0000082//G1/S transition of mitotic cell cycle","K06628//cell division control protein 45","NP_001171481.1//cell division control protein 45 homolog isoform 1 [Homo sapiens];NP_003495.1//cell division control protein 45 homolog isoform 2 [Homo sapiens];NP_001171482.1//cell division control protein 45 homolog isoform 3 [Homo sapiens]","4;2//1"]
[8878,2917,597.5,654.6,0.13167488928929,{"v":8.46509901754386e-22,"d":"8.47E-22"},"*",{"v":3.62472e-23,"d":"3.62E-23"},"SQSTM1","GO:0005783//endoplasmic reticulum;GO:0005770//late endosome;GO:0000932//P-body;GO:0016234//inclusion body;GO:0005737//cytoplasm;GO:0044754//autolysosome;GO:0005829//cytosol;GO:0005776//autophagosome;GO:0070062//extracellular exosome;GO:0043231//intracellular membrane-bounded organelle;GO:0005654//nucleoplasm;GO:0016605//PML body;GO:0016235//aggresome;GO:0044753//amphisome;GO:0097413//Lewy body;GO:0000407//phagophore assembly site;GO:0097225//sperm midpiece","GO:0042802//identical protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0030971//receptor tyrosine kinase binding;GO:0042803//protein homodimerization activity;GO:0042169//SH2 domain binding;GO:0019901//protein kinase binding;GO:0070530//K63-linked polyubiquitin modification-dependent protein binding;GO:0043130//ubiquitin binding;GO:0005080//protein kinase C binding;GO:0004674//protein serine/threonine kinase activity;GO:0008270//zinc ion binding;GO:0035255//ionotropic glutamate receptor binding;GO:0019899//enzyme binding","GO:0006950//response to stress;GO:0035556//intracellular signal transduction;GO:0035973//aggrephagy;GO:0000422//autophagy of mitochondrion;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0043065//positive regulation of apoptotic process;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0046578//regulation of Ras protein signal transduction;GO:0002376//immune system process;GO:0001934//positive regulation of protein phosphorylation;GO:1903078//positive regulation of protein localization to plasma membrane;GO:0006914//autophagy;GO:0010821//regulation of mitochondrion organization;GO:1905719//protein localization to perinuclear region of cytoplasm;GO:0061635//regulation of protein complex stability;GO:0002931//response to ischemia;GO:0051291//protein heterooligomerization;GO:0016197//endosomal transport;GO:1900273//positive regulation of long-term synaptic potentiation;GO:0030154//cell differentiation;GO:0043066//negative regulation of apoptotic process;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0006915//apoptotic process;GO:0000423//mitophagy;GO:0044130//negative regulation of growth of symbiont in host;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0008104//protein localization;GO:0098780//response to mitochondrial depolarisation;GO:0007032//endosome organization;GO:0016236//macroautophagy","K14381//sequestosome 1","NP_003891.1//sequestosome-1 isoform 1 [Homo sapiens];XP_001153075.1//PREDICTED: sequestosome-1 isoform X1 [Pan troglodytes]","4;1//3"]
[8563,2565,15.89,17.4,0.130968181387571,0.387122771134844,"*",0.242806,"THOC5","GO:0000784//nuclear chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000347//THO complex;GO:0000445//THO complex part of transcription export complex;GO:0005737//cytoplasm;GO:0000346//transcription export complex","GO:0003729//mRNA binding","GO:0006406//mRNA export from nucleus;GO:0060215//primitive hemopoiesis;GO:0046784//viral mRNA export from host cell nucleus;GO:0006369//termination of RNA polymerase II transcription;GO:0031124//mRNA 3'-end processing;GO:2000002//negative regulation of DNA damage checkpoint;GO:0006405//RNA export from nucleus;GO:0032786//positive regulation of DNA-templated transcription, elongation;GO:0008380//RNA splicing;GO:0030224//monocyte differentiation","K13174//THO complex subunit 5","EAW59807.1//hCG2011153, isoform CRA_a [Homo sapiens]","1//3;4"]
[51654,1996,15.94,17.45,0.130575407106543,0.271800599042646,"*",0.1564036,"CDK5RAP1","GO:0005739//mitochondrion;GO:0005737//cytoplasm","GO:0035597//N6-isopentenyladenosine methylthiotransferase activity;GO:0046872//metal ion binding;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0032403//protein complex binding","GO:0006400//tRNA modification;GO:0070131//positive regulation of mitochondrial translation;GO:0045664//regulation of neuron differentiation;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0070900//mitochondrial tRNA modification;GO:0007420//brain development;GO:0045903//positive regulation of translational fidelity","K15865//threonylcarbamoyladenosine tRNA methylthiotransferase CDKAL1 [EC:2.8.4.5]","XP_003273580.1//PREDICTED: CDK5 regulatory subunit-associated protein 1 isoform X1 [Nomascus leucogenys];NP_057166.4//CDK5 regulatory subunit-associated protein 1 isoform b [Homo sapiens];XP_003273581.1//PREDICTED: CDK5 regulatory subunit-associated protein 1 isoform X5 [Nomascus leucogenys];NP_001265098.1//CDK5 regulatory subunit-associated protein 1 isoform e [Homo sapiens];XP_012367331.1//PREDICTED: CDK5 regulatory subunit-associated protein 1 isoform X2 [Nomascus leucogenys]","4;1//3;3//A2MP1"]
[5732,2494,0.32,0.35,0.129283016944966,0.890079791442411,"*",0.82823,"PTGER2","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005622//intracellular;GO:0005886//plasma membrane","GO:0004957//prostaglandin E receptor activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0071380//cellular response to prostaglandin E stimulus;GO:0042127//regulation of cell proliferation;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0032496//response to lipopolysaccharide;GO:0032570//response to progesterone","K04259//prostaglandin E receptor 2","NP_000947.2//prostaglandin E2 receptor EP2 subtype [Homo sapiens]","3//A2MP1"]
[116224,3874,4.81,5.26,0.12902590552226,0.460807130998703,"*",0.311378,"FAM122A","NA","NA","NA","NA","NP_612206.4//protein FAM122A [Homo sapiens]",4]
[6595,3634,5.68,6.21,0.1287023387158,{"v":1.35749459041096E-7,"d":"1.36E-07"},"*",{"v":1.985168e-08,"d":"1.99E-08"},"SMARCA2","GO:0005654//nucleoplasm;GO:0045111//intermediate filament cytoskeleton;GO:0016514//SWI/SNF complex","GO:0042393//histone binding;GO:0005524//ATP binding;GO:0001105//RNA polymerase II transcription coactivator activity;GO:0044212//transcription regulatory region DNA binding;GO:0016887//ATPase activity","GO:0030308//negative regulation of cell growth;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0008285//negative regulation of cell proliferation","K11647//SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:3.6.4.-]","XP_014973296.1//PREDICTED: probable global transcription activator SNF2L2 isoform X1 [Macaca mulatta];XP_011811864.1//PREDICTED: probable global transcription activator SNF2L2 isoform X3 [Colobus angolensis palliatus];NP_001276329.1//probable global transcription activator SNF2L2 isoform f precursor [Homo sapiens];NP_001276327.1//probable global transcription activator SNF2L2 isoform d [Homo sapiens];BAA05142.1//transcriptional activator hSNF2a [Homo sapiens]","1//3;4;3//A2MP1"]
[387787,2330,1.61,1.76,0.12851474052268,0.778059630822065,"*",0.68079,"LIPT2","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0033819//lipoyl(octanoyl) transferase activity;GO:0016874//ligase activity","GO:0006464//cellular protein modification process;GO:0034641//cellular nitrogen compound metabolic process;GO:0009249//protein lipoylation;GO:0009107//lipoate biosynthetic process","K03801//lipoyl(octanoyl) transferase [EC:2.3.1.181]","XP_008965688.2//PREDICTED: putative lipoyltransferase 2, mitochondrial isoform X2 [Pan paniscus];NP_001316871.1//putative lipoyltransferase 2, mitochondrial isoform 3 precursor [Homo sapiens];EAW74939.1//hCG27406, isoform CRA_a [Homo sapiens]","1//3;2//1"]
[51668,614,34.36,37.55,0.12808287126317,0.449611039358329,"*",0.301786,"HSPB11","GO:0030992//intraciliary transport particle B;GO:0070062//extracellular exosome;GO:0005929//cilium;GO:0097542//ciliary tip;GO:0005813//centrosome","GO:0046872//metal ion binding","GO:0030324//lung development;GO:0042073//intraciliary transport;GO:0070986//left/right axis specification;GO:0007507//heart development;GO:0035735//intraciliary transport involved in cilium assembly;GO:0007224//smoothened signaling pathway;GO:0001501//skeletal system development","K19369//heat shock protein beta-11","XP_008966123.1//PREDICTED: intraflagellar transport protein 25 homolog isoform X1 [Pan paniscus]","1//3;3//A2MP1"]
[79096,1690,20.54,22.44,0.127636494290598,0.397374329491525,"*",0.256848,"C11orf49","NA","NA","NA","NA","NP_001265151.1//UPF0705 protein C11orf49 isoform 5 [Homo sapiens];NP_001003677.1//UPF0705 protein C11orf49 isoform 2 [Homo sapiens];NP_077018.1//UPF0705 protein C11orf49 isoform 3 [Homo sapiens];XP_008541417.1//PREDICTED: UPF0705 protein C11orf49 homolog isoform X2 [Equus przewalskii];NP_001003678.1//UPF0705 protein C11orf49 isoform 4 [Homo sapiens]","1//3;4;2//1"]
[27349,2086,11.1,12.12,0.126830022235483,0.462551221173422,"*",0.312904,"MCAT","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0003723//RNA binding;GO:0016740//transferase activity;GO:0004314//[acyl-carrier-protein] S-malonyltransferase activity","GO:0006635//fatty acid beta-oxidation;GO:0008152//metabolic process;GO:0006633//fatty acid biosynthetic process","K00645//[acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]","XP_006934209.1//PREDICTED: malonyl-CoA-acyl carrier protein transacylase, mitochondrial isoform X2 [Felis catus];NP_775738.3//malonyl-CoA-acyl carrier protein transacylase, mitochondrial isoform a precursor [Homo sapiens]","4;3//A2MP1"]
[81544,3235,2.07,2.26,0.126692004915862,0.661405455296367,"*",0.541372,"GDPD5","GO:0030424//axon;GO:0030426//growth cone;GO:0097038//perinuclear endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0043025//neuronal cell body","GO:0047389//glycerophosphocholine phosphodiesterase activity;GO:0008889//glycerophosphodiester phosphodiesterase activity","GO:0045666//positive regulation of neuron differentiation;GO:0021895//cerebral cortex neuron differentiation;GO:0048505//regulation of timing of cell differentiation;GO:0045746//negative regulation of Notch signaling pathway;GO:0031175//neuron projection development;GO:0021522//spinal cord motor neuron differentiation;GO:0006629//lipid metabolic process;GO:0045787//positive regulation of cell cycle","K01124//glycerophosphoinositol inositolphosphodiesterase [EC:3.1.4.43]","NP_110419.5//glycerophosphodiester phosphodiesterase domain-containing protein 5 isoform 1 [Homo sapiens];XP_010365096.1//PREDICTED: glycerophosphodiester phosphodiesterase domain-containing protein 5 isoform X3 [Rhinopithecus roxellana];XP_010810998.1//PREDICTED: glycerophosphodiester phosphodiesterase domain-containing protein 5 isoform X3 [Bos taurus]","1//3;7"]
[4034,3255,16.07,17.54,0.126278818769639,0.18635057283189,"*",0.0983316,"LRCH4","GO:0016323//basolateral plasma membrane;GO:0016605//PML body;GO:0016021//integral component of membrane;GO:0005737//cytoplasm","NA","GO:0007399//nervous system development;GO:0007165//signal transduction;GO:0045199//maintenance of epithelial cell apical/basal polarity","K10130//leucine-rich repeats and death domain-containing protein","EAW76519.1//leucine-rich repeats and calponin homology (CH) domain containing 4, isoform CRA_a [Homo sapiens];NP_001276863.1//leucine-rich repeat and calponin homology domain-containing protein 4 isoform 2 [Homo sapiens]","1//3;4"]
[84957,3458,5.7,6.22,0.125952661078498,0.428834167330677,"*",0.283008,"RELT","GO:0070062//extracellular exosome;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005737//cytoplasm","GO:0005031//tumor necrosis factor-activated receptor activity","GO:0007275//multicellular organism development;GO:0097190//apoptotic signaling pathway;GO:0042127//regulation of cell proliferation;GO:0006955//immune response;GO:0032496//response to lipopolysaccharide;GO:0042981//regulation of apoptotic process;GO:0006954//inflammatory response","K05156//tumor necrosis factor receptor superfamily member 19-like","EAW74895.1//tumor necrosis factor receptor superfamily, member 19-like, isoform CRA_c [Homo sapiens]","1//3;3//A2MP1"]
[23378,1762,12.16,13.26,0.124937546669002,0.445793202543482,"*",0.298442,"RRP8","GO:0033553//rDNA heterochromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005677//chromatin silencing complex;GO:0005886//plasma membrane","GO:0008757//S-adenosylmethionine-dependent methyltransferase activity;GO:0003723//RNA binding;GO:0008168//methyltransferase activity;GO:0035064//methylated histone binding","GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:0006351//transcription, DNA-templated;GO:0046015//regulation of transcription by glucose;GO:0006364//rRNA processing;GO:0042149//cellular response to glucose starvation;GO:0071158//positive regulation of cell cycle arrest;GO:0016569//covalent chromatin modification;GO:0000183//chromatin silencing at rDNA","K14850//ribosomal RNA-processing protein 8 [EC:2.1.1.287]","NP_056139.1//ribosomal RNA-processing protein 8 [Homo sapiens]","3//A2MP1"]
[4802,2134,27.34,29.81,0.124783132385109,0.10821434669487,"*",0.0512416,"NFYC","GO:0090575//RNA polymerase II transcription factor complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016602//CCAAT-binding factor complex;GO:0032993//protein-DNA complex","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003713//transcription coactivator activity;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0008134//transcription factor binding","GO:0006457//protein folding;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006355//regulation of transcription, DNA-templated;GO:0045540//regulation of cholesterol biosynthetic process","K08066//nuclear transcription factor Y, gamma","BAD92212.1//nuclear transcription factor Y, gamma variant, partial [Homo sapiens];NP_001136062.1//nuclear transcription factor Y subunit gamma isoform 5 [Homo sapiens];XP_016815513.1//PREDICTED: nuclear transcription factor Y subunit gamma isoform X1 [Pan troglodytes];XP_009453310.2//PREDICTED: nuclear transcription factor Y subunit gamma isoform X2 [Pan troglodytes]","4;1//3"]
[7137,866,2.11,2.3,0.12439086223719,0.841407210895584,"*",0.765768,"TNNI3","GO:0005829//cytosol;GO:0097512//cardiac myofibril;GO:0005861//troponin complex;GO:0030017//sarcomere;GO:1990584//cardiac Troponin complex","GO:0051015//actin filament binding;GO:0019855//calcium channel inhibitor activity;GO:0030172//troponin C binding;GO:0019901//protein kinase binding;GO:0003779//actin binding;GO:0046872//metal ion binding;GO:0019904//protein domain specific binding;GO:0048306//calcium-dependent protein binding;GO:0031014//troponin T binding","GO:0010882//regulation of cardiac muscle contraction by calcium ion signaling;GO:1903779//regulation of cardiac conduction;GO:0032780//negative regulation of ATPase activity;GO:0030049//muscle filament sliding;GO:0007507//heart development;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0006940//regulation of smooth muscle contraction;GO:0001980//regulation of systemic arterial blood pressure by ischemic conditions;GO:0060048//cardiac muscle contraction;GO:0060047//heart contraction;GO:0001570//vasculogenesis;GO:0003009//skeletal muscle contraction;GO:0006874//cellular calcium ion homeostasis","K12044//troponin I, cardiac muscle","NP_000354.4//troponin I, cardiac muscle [Homo sapiens]",4]
[55070,2312,4.36,4.75,0.123599378441384,0.723391965527489,"*",0.609544,"DET1","GO:0080008//Cul4-RING E3 ubiquitin ligase complex;GO:0005634//nucleus;GO:0031464//Cul4A-RING E3 ubiquitin ligase complex","GO:1990756//protein binding, bridging involved in substrate recognition for ubiquitination;GO:0031625//ubiquitin protein ligase binding;GO:0032403//protein complex binding","GO:0016567//protein ubiquitination;GO:0006461//protein complex assembly;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process","K10571//de-etiolated-1","XP_003986864.1//PREDICTED: DET1 homolog isoform X2 [Felis catus];XP_012499152.1//PREDICTED: DET1 homolog isoform X1 [Propithecus coquereli];NP_001308523.1//DET1 homolog isoform 3 [Homo sapiens];NP_060466.2//DET1 homolog isoform 1 [Homo sapiens]","4;1//3;2//1"]
[2029,1309,76.68,83.51,0.123098628084681,0.0251868381850591,"*",0.00973006,"ENSA","GO:0005654//nucleoplasm;GO:0005737//cytoplasm","GO:0004864//protein phosphatase inhibitor activity;GO:0019870//potassium channel inhibitor activity;GO:0008200//ion channel inhibitor activity;GO:0005102//receptor binding;GO:0019888//protein phosphatase regulator activity;GO:0051721//protein phosphatase 2A binding;GO:0019212//phosphatase inhibitor activity","GO:0006810//transport;GO:0035308//negative regulation of protein dephosphorylation;GO:0000278//mitotic cell cycle;GO:0051301//cell division;GO:0007584//response to nutrient;GO:0009749//response to glucose;GO:0000086//G2/M transition of mitotic cell cycle;GO:0007049//cell cycle;GO:0050796//regulation of insulin secretion","K02539//myeloid leukemia cell differntiation protein MCL-1","NP_996925.1//alpha-endosulfine isoform 1 [Homo sapiens];XP_003817346.2//PREDICTED: alpha-endosulfine isoform X1 [Pan paniscus];NP_004427.1//alpha-endosulfine isoform 3 [Homo sapiens];EAW53534.1//hCG1999134 [Homo sapiens];NP_996928.1//alpha-endosulfine isoform 5 [Homo sapiens];NP_997051.1//alpha-endosulfine isoform 8 [Homo sapiens]","1//3;2//1"]
[79089,2230,27.66,30.12,0.122920613521434,0.348969197242515,"*",0.212322,"TMUB2","GO:0016021//integral component of membrane","NA","NA","K08290//Fas-activated serine/threonine kinase [EC:2.7.11.8]","XP_011523502.1//PREDICTED: transmembrane and ubiquitin-like domain-containing protein 2 isoform X1 [Homo sapiens];AAL55748.1//unknown [Homo sapiens];XP_008974295.2//PREDICTED: transmembrane and ubiquitin-like domain-containing protein 2 isoform X2 [Pan paniscus];XP_020020264.1//LOW QUALITY PROTEIN: transmembrane and ubiquitin-like domain-containing protein 2 [Castor canadensis];XP_011841287.1//PREDICTED: transmembrane and ubiquitin-like domain-containing protein 2 isoform X2 [Mandrillus leucophaeus];XP_008974310.2//PREDICTED: transmembrane and ubiquitin-like domain-containing protein 2 isoform X1 [Pan paniscus];XP_003270795.1//PREDICTED: transmembrane and ubiquitin-like domain-containing protein 2 isoform X1 [Nomascus leucogenys]","1//3;3//A2MP1;2//1"]
[4864,4827,19,20.67,0.121538970207137,0.0757522577777778,"*",0.0339306,"NPC1","GO:0016020//membrane;GO:0005765//lysosomal membrane;GO:0070062//extracellular exosome;GO:0005783//endoplasmic reticulum;GO:0005635//nuclear envelope;GO:0031902//late endosome membrane;GO:0005764//lysosome;GO:0048471//perinuclear region of cytoplasm;GO:0045121//membrane raft;GO:0005887//integral component of plasma membrane;GO:0005794//Golgi apparatus;GO:0005576//extracellular region;GO:0016021//integral component of membrane","GO:0015248//sterol transporter activity;GO:0004872//receptor activity;GO:0015485//cholesterol binding;GO:0004888//transmembrane signaling receptor activity;GO:0001618//virus receptor activity","GO:0007041//lysosomal transport;GO:0006486//protein glycosylation;GO:0071404//cellular response to low-density lipoprotein particle stimulus;GO:0008203//cholesterol metabolic process;GO:0030301//cholesterol transport;GO:0033344//cholesterol efflux;GO:2000189//positive regulation of cholesterol homeostasis;GO:0006897//endocytosis;GO:0006914//autophagy;GO:0042632//cholesterol homeostasis;GO:0071383//cellular response to steroid hormone stimulus;GO:0034383//low-density lipoprotein particle clearance;GO:0042493//response to drug;GO:0046686//response to cadmium ion;GO:0007628//adult walking behavior;GO:0031579//membrane raft organization;GO:0090150//establishment of protein localization to membrane;GO:0060548//negative regulation of cell death;GO:0008206//bile acid metabolic process;GO:0046718//viral entry into host cell;GO:0016242//negative regulation of macroautophagy","K12385//Niemann-Pick C1 protein","BAD92285.1//Niemann-Pick disease, type C1 variant, partial [Homo sapiens]",4]
[6921,1967,26.42,28.74,0.121429595210509,0.200048931285898,"*",0.1068372,"ELOC","NA","NA","NA","K03872//transcription elongation factor B, polypeptide 1","XP_021544320.1//elongin-C isoform X1 [Neomonachus schauinslandi];XP_021574588.1//elongin-C isoform X1 [Carlito syrichta];XP_007116506.1//PREDICTED: transcription elongation factor B polypeptide 1 isoform X1 [Physeter catodon];XP_007116508.1//PREDICTED: transcription elongation factor B polypeptide 1 isoform X3 [Physeter catodon]","1//3;3//A2MP1"]
[11336,2774,15.15,16.47,0.120522761366041,0.271327415153495,"*",0.1560294,"EXOC3","GO:0000145//exocyst","GO:0000149//SNARE binding;GO:0045296//cadherin binding","GO:0051601//exocyst localization;GO:0006887//exocytosis","K06110//exocyst complex component 3","O60645.2//RecName: Full=Exocyst complex component 3; AltName: Full=Exocyst complex component Sec6",4]
[637,2147,16.11,17.51,0.120222589726989,0.343291455467053,"*",0.20775,"BID","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005737//cytoplasm;GO:0032592//integral component of mitochondrial membrane","GO:0005123//death receptor binding;GO:0031625//ubiquitin protein ligase binding;GO:0046982//protein heterodimerization activity","GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:0097284//hepatocyte apoptotic process;GO:0034349//glial cell apoptotic process;GO:0097191//extrinsic apoptotic signaling pathway;GO:0051402//neuron apoptotic process;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0042127//regulation of cell proliferation;GO:0008637//apoptotic mitochondrial changes;GO:0051260//protein homooligomerization;GO:0007420//brain development;GO:0010918//positive regulation of mitochondrial membrane potential;GO:1902230//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage;GO:0043065//positive regulation of apoptotic process;GO:0032355//response to estradiol;GO:0097345//mitochondrial outer membrane permeabilization;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:0001836//release of cytochrome c from mitochondria;GO:1900740//positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway;GO:0032464//positive regulation of protein homooligomerization;GO:0032461//positive regulation of protein oligomerization;GO:0006626//protein targeting to mitochondrion;GO:0042770//signal transduction in response to DNA damage;GO:1901030//positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0042775//mitochondrial ATP synthesis coupled electron transport;GO:0090150//establishment of protein localization to membrane;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0042981//regulation of apoptotic process;GO:2000271//positive regulation of fibroblast apoptotic process","K04726//BH3 interacting domain death agonist","ACA61804.1//Bid precursor, partial [Homo sapiens];NP_932070.1//BH3-interacting domain death agonist isoform 1 [Homo sapiens];AAH22072.2//BID protein, partial [Homo sapiens];XP_011840009.1//PREDICTED: BH3-interacting domain death agonist isoform X2 [Mandrillus leucophaeus]","1//3;3//A2MP1;2//1"]
[5510,1434,31.57,34.31,0.120074865244669,0.105250298593045,"*",0.0496404,"PPP1R7","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005694//chromosome;GO:0005737//cytoplasm","GO:0030234//enzyme regulator activity;GO:0019888//protein phosphatase regulator activity","GO:0007059//chromosome segregation;GO:0035307//positive regulation of protein dephosphorylation","K17550//protein phosphatase 1 regulatory subunit 7","NP_001269343.1//protein phosphatase 1 regulatory subunit 7 isoform 7 [Homo sapiens];XP_010375308.1//PREDICTED: protein phosphatase 1 regulatory subunit 7 isoform X4 [Rhinopithecus roxellana];NP_001269341.1//protein phosphatase 1 regulatory subunit 7 isoform 5 [Homo sapiens];NP_001269342.1//protein phosphatase 1 regulatory subunit 7 isoform 6 [Homo sapiens];XP_005574921.1//PREDICTED: protein phosphatase 1 regulatory subunit 7 isoform X3 [Macaca fascicularis];NP_001271924.1//protein phosphatase 1 regulatory subunit 7 [Macaca fascicularis];XP_010375307.1//PREDICTED: protein phosphatase 1 regulatory subunit 7 isoform X3 [Rhinopithecus roxellana]","1//3;2//1"]
[143244,3849,6.97,7.57,0.119134644117309,0.406103673634525,"*",0.263914,"EIF5AL1","NA","NA","NA","K03263//translation initiation factor 5A","AAH70048.1//EIF5AL1 protein, partial [Homo sapiens]","1//3"]
[4351,2986,19.55,21.22,0.11825604872005,0.361988678984772,"*",0.223212,"MPI","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0008270//zinc ion binding;GO:0004476//mannose-6-phosphate isomerase activity","GO:0000032//cell wall mannoprotein biosynthetic process;GO:0006486//protein glycosylation;GO:0005975//carbohydrate metabolic process;GO:0061611//mannose to fructose-6-phosphate metabolic process;GO:0009298//GDP-mannose biosynthetic process","K01809//mannose-6-phosphate isomerase [EC:5.3.1.8]","NP_002426.1//mannose-6-phosphate isomerase isoform 1 [Homo sapiens];NP_001276084.1//mannose-6-phosphate isomerase isoform 2 [Homo sapiens];NP_001276086.1//mannose-6-phosphate isomerase isoform 4 [Homo sapiens];XP_011519894.1//PREDICTED: mannose-6-phosphate isomerase isoform X1 [Homo sapiens]","1//3;2//1"]
[114049,1257,83,90.09,0.118255639156656,0.0667123425801853,"*",0.0292968,"BUD23","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0048471//perinuclear region of cytoplasm","GO:0003723//RNA binding;GO:0016435//rRNA (guanine) methyltransferase activity;GO:0008168//methyltransferase activity;GO:0046982//protein heterodimerization activity","GO:0031167//rRNA methylation;GO:0006355//regulation of transcription, DNA-templated;GO:0016569//covalent chromatin modification;GO:0006351//transcription, DNA-templated;GO:0070476//rRNA (guanine-N7)-methylation;GO:2000234//positive regulation of rRNA processing","K19306//18S rRNA (guanine1575-N7)-methyltransferase [EC:2.1.1.309]","NP_001189489.1//probable 18S rRNA (guanine-N(7))-methyltransferase isoform 1 [Homo sapiens];NP_059998.2//probable 18S rRNA (guanine-N(7))-methyltransferase isoform 2 [Homo sapiens]","4;2//1"]
[1663,3775,43.3,46.96,0.117065383495965,0.0224676057443658,"*",0.00855018,"DDX11","GO:0070062//extracellular exosome;GO:0031390//Ctf18 RFC-like complex;GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005813//centrosome;GO:0000790//nuclear chromatin;GO:0005737//cytoplasm;GO:0030496//midbody;GO:0005730//nucleolus;GO:0001650//fibrillar center","GO:0003688//DNA replication origin binding;GO:0003677//DNA binding;GO:0005524//ATP binding;GO:0004386//helicase activity;GO:0003690//double-stranded DNA binding;GO:0008186//RNA-dependent ATPase activity;GO:0008026//ATP-dependent helicase activity;GO:0003697//single-stranded DNA binding;GO:0003682//chromatin binding;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0051880//G-quadruplex DNA binding;GO:0003727//single-stranded RNA binding;GO:0045142//triplex DNA binding;GO:0004003//ATP-dependent DNA helicase activity;GO:0046872//metal ion binding;GO:0008094//DNA-dependent ATPase activity","GO:0035563//positive regulation of chromatin binding;GO:0032508//DNA duplex unwinding;GO:1901838//positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter;GO:0072711//cellular response to hydroxyurea;GO:1990700//nucleolar chromatin organization;GO:0036498//IRE1-mediated unfolded protein response;GO:0032091//negative regulation of protein binding;GO:1904976//cellular response to bleomycin;GO:0006974//cellular response to DNA damage stimulus;GO:0006281//DNA repair;GO:0006139//nucleobase-containing compound metabolic process;GO:0006351//transcription, DNA-templated;GO:0016032//viral process;GO:0044806//G-quadruplex DNA unwinding;GO:0007062//sister chromatid cohesion;GO:0072719//cellular response to cisplatin;GO:0007275//multicellular organism development;GO:0031297//replication fork processing;GO:2000781//positive regulation of double-strand break repair;GO:0032079//positive regulation of endodeoxyribonuclease activity;GO:0045876//positive regulation of sister chromatid cohesion","K11273//chromosome transmission fidelity protein 1 [EC:3.6.4.13]","Q92771.3//PUTATIVE PSEUDOGENE: RecName: Full=Putative ATP-dependent RNA helicase DDX12; AltName: Full=CHL1-related protein 2; Short=hCHLR2; AltName: Full=DEAD/H box protein 12;XP_005253388.1//PREDICTED: probable ATP-dependent DNA helicase DDX11 isoform X10 [Homo sapiens];XP_011518897.1//PREDICTED: probable ATP-dependent DNA helicase DDX11 isoform X16 [Homo sapiens];XP_005253390.1//PREDICTED: probable ATP-dependent DNA helicase DDX11 isoform X13 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[83856,7651,0.71,0.77,0.117039421190219,0.199606786297513,"*",0.1065136,"FSD1L","GO:0005622//intracellular","NA","NA","K08285//midline 1 [EC:2.3.2.27];K10647//midline 2 [EC:2.3.2.27];K10655//tripartite motif-containing protein 63 [EC:2.3.2.27]","NP_001274120.1//FSD1-like protein isoform 4 [Homo sapiens];NP_001138785.1//FSD1-like protein isoform 3 [Homo sapiens];NP_001317668.1//FSD1-like protein isoform 6 [Homo sapiens];NP_114125.1//FSD1-like protein isoform 2 [Homo sapiens];NP_001274121.1//FSD1-like protein isoform 5 [Homo sapiens]","4;1//3;2//1"]
[6144,582,411.14,445.73,0.116540326073599,0.00483083724849192,"*",0.00155413,"RPL21","GO:0016020//membrane;GO:0005840//ribosome;GO:0005829//cytosol;GO:0022625//cytosolic large ribosomal subunit","GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome","GO:0006413//translational initiation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0019083//viral transcription;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006412//translation;GO:0006364//rRNA processing","K02889//large subunit ribosomal protein L21e","NP_000973.2//60S ribosomal protein L21 [Homo sapiens]","3//A2MP1"]
[10241,3682,20.13,21.81,0.115642597719411,0.140306068045631,"*",0.0700652,"CALCOCO2","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0031410//cytoplasmic vesicle;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0005829//cytosol;GO:0005776//autophagosome;GO:0000421//autophagosome membrane","GO:0042803//protein homodimerization activity","GO:0098792//xenophagy;GO:1901098//positive regulation of autophagosome maturation;GO:0034341//response to interferon-gamma;GO:0016032//viral process","K21348//calcium-binding and coiled-coil domain-containing protein 2","NP_001248322.1//calcium-binding and coiled-coil domain-containing protein 2 isoform 4 [Homo sapiens];NP_001248319.1//calcium-binding and coiled-coil domain-containing protein 2 isoform 1 [Homo sapiens];NP_005822.1//calcium-binding and coiled-coil domain-containing protein 2 isoform 3 [Homo sapiens];NP_001248320.1//calcium-binding and coiled-coil domain-containing protein 2 isoform 2 [Homo sapiens]","4;1//3"]
[54867,2998,61.49,66.61,0.115386975093947,0.00941863372334609,"*",0.00323526,"TMEM214","GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005881//cytoplasmic microtubule;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","NA","GO:0006915//apoptotic process","NA","NP_060197.4//transmembrane protein 214 isoform 1 [Homo sapiens];NP_001077059.1//transmembrane protein 214 isoform 2 [Homo sapiens]","4;1//3"]
[51172,2209,7.83,8.48,0.115051957272159,0.539938014736842,"*",0.385332,"NAGPA","GO:0005887//integral component of plasma membrane;GO:0032580//Golgi cisterna membrane;GO:0016021//integral component of membrane","GO:0003944//N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase activity","GO:0006622//protein targeting to lysosome;GO:0006486//protein glycosylation;GO:0006464//cellular protein modification process;GO:0005975//carbohydrate metabolic process;GO:0033299//secretion of lysosomal enzymes;GO:0007040//lysosome organization","K01125//N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase [EC:3.1.4.45]","NP_057340.2//N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor [Homo sapiens]","3//A2MP1"]
[51227,850,12.02,13.01,0.11418406600661,0.865105346480789,"*",0.79638,"PIGP","GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0000506//glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex","GO:0017176//phosphatidylinositol N-acetylglucosaminyltransferase activity","GO:0006506//GPI anchor biosynthetic process;GO:0016254//preassembly of GPI anchor in ER membrane","K03861//phosphatidylinositol glycan, class P","BAA96872.1//DSCR5b [Homo sapiens];NP_710148.1//phosphatidylinositol N-acetylglucosaminyltransferase subunit P isoform 1 [Homo sapiens];XP_009200524.2//phosphatidylinositol N-acetylglucosaminyltransferase subunit P isoform X1 [Papio anubis];NP_057514.2//phosphatidylinositol N-acetylglucosaminyltransferase subunit P isoform 3 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[8312,3576,19.54,21.14,0.113544909414298,0.179848402105011,"*",0.094135,"AXIN1","NA","NA","NA","K02157//axin 1","XP_016879233.1//PREDICTED: axin-1 isoform X4 [Homo sapiens];XP_016879232.1//PREDICTED: axin-1 isoform X2 [Homo sapiens]","3//A2MP1;2//1"]
[5833,4067,9.8,10.6,0.113210610447991,0.266361394936709,"*",0.1528068,"PCYT2","GO:0005789//endoplasmic reticulum membrane","GO:0004306//ethanolamine-phosphate cytidylyltransferase activity;GO:0016779//nucleotidyltransferase activity;GO:0003824//catalytic activity","GO:0008654//phospholipid biosynthetic process;GO:0006646//phosphatidylethanolamine biosynthetic process;GO:0009058//biosynthetic process","K00967//ethanolamine-phosphate cytidylyltransferase [EC:2.7.7.14]","XP_017380312.1//PREDICTED: ethanolamine-phosphate cytidylyltransferase isoform X6 [Cebus capucinus imitator];XP_017380309.1//PREDICTED: ethanolamine-phosphate cytidylyltransferase isoform X3 [Cebus capucinus imitator];XP_017380310.1//PREDICTED: ethanolamine-phosphate cytidylyltransferase isoform X4 [Cebus capucinus imitator];NP_002852.1//ethanolamine-phosphate cytidylyltransferase isoform 2 [Homo sapiens];NP_001243363.1//ethanolamine-phosphate cytidylyltransferase isoform 3 [Homo sapiens]","4;1//3;2//1"]
[26099,3694,58.12,62.86,0.11310756916591,0.00756606753633992,"*",0.0025416,"SZRD1","NA","NA","NA","K20069//adaptin ear-binding coat-associated protein 1/2","XP_012669158.1//PREDICTED: SUZ domain-containing protein 1-like [Otolemur garnettii]","1//3;2//1"]
[10907,1484,31.13,33.64,0.111872128785965,0.205622655146716,"*",0.1105476,"TXNL4A","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0005681//spliceosomal complex;GO:0005829//cytosol;GO:0005682//U5 snRNP;GO:0046540//U4/U6 x U5 tri-snRNP complex","NA","GO:0000398//mRNA splicing, via spliceosome;GO:0051301//cell division;GO:0000245//spliceosomal complex assembly;GO:0007049//cell cycle;GO:0000375//RNA splicing, via transesterification reactions","K12859//U5 snRNP protein, DIM1 family","XP_016287227.1//PREDICTED: thioredoxin-like protein 4A isoform X3 [Monodelphis domestica];XP_021006483.1//thioredoxin-like protein 4A isoform X2 [Mus caroli];XP_004861963.2//thioredoxin-like protein 4A isoform X1 [Heterocephalus glaber];NP_001292486.1//thioredoxin-like protein 4A isoform 3 [Homo sapiens];XP_008011890.1//PREDICTED: thioredoxin-like protein 4A isoform X1 [Chlorocebus sabaeus]","4;1//3;2//1"]
[9670,4041,12.6,13.61,0.111243333116716,0.255245536456841,"*",0.1449438,"IPO13","GO:0005634//nucleus;GO:0031965//nuclear membrane;GO:0005737//cytoplasm","GO:0008536//Ran GTPase binding;GO:0008565//protein transporter activity;GO:0008139//nuclear localization sequence binding","GO:0006886//intracellular protein transport;GO:0006606//protein import into nucleus","K15436//transportin-3","BAC98010.2//mKIAA0724 protein, partial [Mus musculus]","3//A2MP1"]
[686,3282,7.28,7.86,0.11059086205991,0.97788886700917,"*",0.941342,"BTD","GO:0005759//mitochondrial matrix;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005576//extracellular region","GO:0047708//biotinidase activity;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0016810//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds","GO:0006807//nitrogen compound metabolic process;GO:0006768//biotin metabolic process;GO:0007417//central nervous system development","K01435//biotinidase [EC:3.5.1.12]","NP_001268653.1//biotinidase isoform 2 [Homo sapiens];NP_000051.1//biotinidase isoform 3 [Homo sapiens];NP_001268655.1//biotinidase isoform 5 [Homo sapiens];XP_005545767.1//PREDICTED: biotinidase isoform X1 [Macaca fascicularis];NP_001268652.1//biotinidase isoform 1 [Homo sapiens]","1//3;4;2//1"]
[10629,2176,11.6,12.52,0.110109756917684,0.46708878102796,"*",0.31688,"TAF6L","NA","NA","NA","K03131//transcription initiation factor TFIID subunit 6","XP_021781330.1//TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L [Papio anubis]","3//A2MP1"]
[8131,2826,35.64,38.45,0.109486261327267,0.127916169368907,"*",0.0624286,"NPRL3","GO:0005765//lysosomal membrane;GO:1990130//GATOR1 complex","GO:0005096//GTPase activator activity","GO:0032007//negative regulation of TOR signaling;GO:0034198//cellular response to amino acid starvation;GO:2000785//regulation of autophagosome assembly;GO:0038202//TORC1 signaling;GO:0048738//cardiac muscle tissue development;GO:0035909//aorta morphogenesis;GO:0060021//palate development;GO:0003281//ventricular septum development","K20406//nitrogen permease regulator 3-like protein","NP_001070818.1//GATOR complex protein NPRL3 isoform 1 [Homo sapiens];XP_007978103.1//PREDICTED: nitrogen permease regulator 3-like protein isoform X4 [Chlorocebus sabaeus];NP_001230177.1//GATOR complex protein NPRL3 isoform 4 [Homo sapiens]","1//3;2//1"]
[344167,2698,1.02,1.1,0.108934371553164,0.805577585329867,"*",0.717778,"FOXI3","GO:0005634//nucleus","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0009653//anatomical structure morphogenesis;GO:0030154//cell differentiation;GO:0006351//transcription, DNA-templated","K09401//forkhead box protein I","NP_001129121.1//forkhead box protein I3 [Homo sapiens]","2//1"]
[64866,5991,7.42,8,0.108580813153921,0.288377480017227,"*",0.1676756,"CDCP1","GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane","NA","NA","K06732//CUB domain-containing protein 1","NP_835488.1//CUB domain-containing protein 1 isoform 2 precursor [Homo sapiens];NP_073753.3//CUB domain-containing protein 1 isoform 1 precursor [Homo sapiens]","4;2//1"]
[4729,937,79.02,85.18,0.108296883572667,0.183151774725799,"*",0.0961736,"NDUFV2","GO:0005747//mitochondrial respiratory chain complex I;GO:0043209//myelin sheath;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0009055//electron transfer activity;GO:0046872//metal ion binding;GO:0051537//2 iron, 2 sulfur cluster binding;GO:0008137//NADH dehydrogenase (ubiquinone) activity;GO:0016491//oxidoreductase activity","GO:0007399//nervous system development;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0048738//cardiac muscle tissue development","K03943//NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:1.6.5.3 1.6.99.3]","NP_066552.2//NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial precursor [Homo sapiens]",4]
[139562,1689,1.55,1.67,0.107579887199815,0.868926589705283,"*",0.80104,"OTUD6A","NA","GO:0004843//thiol-dependent ubiquitin-specific protease activity","GO:1990167//protein K27-linked deubiquitination;GO:0035523//protein K29-linked deubiquitination;GO:1990168//protein K33-linked deubiquitination;GO:0035871//protein K11-linked deubiquitination","K18342//OTU domain-containing protein 6 [EC:3.4.19.12]","NP_997203.1//OTU domain-containing protein 6A [Homo sapiens]","2//1"]
[23038,4819,7.91,8.52,0.107175735753046,0.370935671708006,"*",0.230308,"WDTC1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol","GO:0042393//histone binding;GO:0042826//histone deacetylase binding;GO:0004857//enzyme inhibitor activity","GO:0043687//post-translational protein modification;GO:0006006//glucose metabolic process;GO:0008361//regulation of cell size;GO:0016567//protein ubiquitination;GO:0001701//in utero embryonic development;GO:0035264//multicellular organism growth;GO:0032869//cellular response to insulin stimulus;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045717//negative regulation of fatty acid biosynthetic process;GO:0055082//cellular chemical homeostasis","K11807//WD and tetratricopeptide repeats protein 1","NP_055838.2//WD and tetratricopeptide repeats protein 1 isoform b [Homo sapiens];NP_001263181.1//WD and tetratricopeptide repeats protein 1 isoform a [Homo sapiens]","4;1//3"]
[2147,2009,0.52,0.56,0.106915203916512,0.904545782059001,"*",0.846504,"F2","GO:0070062//extracellular exosome;GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0072562//blood microparticle;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005796//Golgi lumen","GO:0004252//serine-type endopeptidase activity;GO:0001530//lipopolysaccharide binding;GO:0008083//growth factor activity;GO:0005509//calcium ion binding;GO:0008201//heparin binding;GO:0070053//thrombospondin receptor activity;GO:0005102//receptor binding","GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0030449//regulation of complement activation;GO:0048712//negative regulation of astrocyte differentiation;GO:0007596//blood coagulation;GO:2000366//positive regulation of STAT protein import into nucleus;GO:0007166//cell surface receptor signaling pathway;GO:0032967//positive regulation of collagen biosynthetic process;GO:0006465//signal peptide processing;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0051918//negative regulation of fibrinolysis;GO:0030193//regulation of blood coagulation;GO:0070945//neutrophil mediated killing of gram-negative bacterium;GO:0044267//cellular protein metabolic process;GO:1900738//positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0009611//response to wounding;GO:0042730//fibrinolysis;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:1900016//negative regulation of cytokine production involved in inflammatory response;GO:0008360//regulation of cell shape;GO:0006508//proteolysis;GO:0051838//cytolysis by host of symbiont cells;GO:0007275//multicellular organism development;GO:0030194//positive regulation of blood coagulation;GO:0017187//peptidyl-glutamic acid carboxylation;GO:0045861//negative regulation of proteolysis;GO:0007597//blood coagulation, intrinsic pathway;GO:0030168//platelet activation;GO:0030307//positive regulation of cell growth;GO:0010544//negative regulation of platelet activation;GO:0001934//positive regulation of protein phosphorylation;GO:1900182//positive regulation of protein localization to nucleus;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0050900//leukocyte migration;GO:0006953//acute-phase response;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0090218//positive regulation of lipid kinase activity;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0008284//positive regulation of cell proliferation","K01313//coagulation factor II (thrombin) [EC:3.4.21.5]","NP_001298186.1//prothrombin isoform 2 [Homo sapiens];NP_000497.1//prothrombin isoform 1 preproprotein [Homo sapiens]","1//3;4"]
[50,2744,36.7,39.51,0.106437783247095,0.1094096900369,"*",0.051972,"ACO2","GO:0005759//mitochondrial matrix;GO:0043209//myelin sheath;GO:0005739//mitochondrion","GO:0003994//aconitate hydratase activity;GO:0046872//metal ion binding;GO:0005506//iron ion binding;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0051538//3 iron, 4 sulfur cluster binding","GO:0006099//tricarboxylic acid cycle;GO:0035900//response to isolation stress;GO:0006101//citrate metabolic process;GO:0001889//liver development;GO:0006102//isocitrate metabolic process;GO:0006091//generation of precursor metabolites and energy","K01681//aconitate hydratase [EC:4.2.1.3]","NP_001089.1//aconitate hydratase, mitochondrial precursor [Homo sapiens]","2//1"]
[57704,3707,18.7,20.12,0.105592035030528,0.249123632473142,"*",0.1408124,"GBA2","GO:0005790//smooth endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0000139//Golgi membrane","GO:0008422//beta-glucosidase activity;GO:0004348//glucosylceramidase activity","GO:0016139//glycoside catabolic process;GO:0021954//central nervous system neuron development;GO:0006680//glucosylceramide catabolic process;GO:0008206//bile acid metabolic process;GO:0006687//glycosphingolipid metabolic process","K17108//non-lysosomal glucosylceramidase [EC:3.2.1.45]","BAB13431.1//KIAA1605 protein, partial [Homo sapiens];NP_065995.1//non-lysosomal glucosylceramidase isoform 1 [Homo sapiens]","1//3;2//1"]
[11315,921,113.08,121.59,0.104680792936822,0.117676593288941,"*",0.056422,"PARK7","GO:0070062//extracellular exosome;GO:0005759//mitochondrial matrix;GO:0030424//axon;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0000785//chromatin;GO:0098793//presynapse;GO:0005758//mitochondrial intermembrane space;GO:0043005//neuron projection;GO:0044297//cell body;GO:0005913//cell-cell adherens junction;GO:0005829//cytosol","GO:0050681//androgen receptor binding;GO:1903135//cupric ion binding;GO:0005507//copper ion binding;GO:1903136//cuprous ion binding;GO:0051920//peroxiredoxin activity;GO:0045296//cadherin binding","GO:0031397//negative regulation of protein ubiquitination;GO:0032148//activation of protein kinase B activity;GO:1902958//positive regulation of mitochondrial electron transport, NADH to ubiquinone;GO:1903428//positive regulation of reactive oxygen species biosynthetic process;GO:0042177//negative regulation of protein catabolic process;GO:0008344//adult locomotory behavior;GO:0033864//positive regulation of NAD(P)H oxidase activity;GO:0010273//detoxification of copper ion;GO:0030073//insulin secretion;GO:0042593//glucose homeostasis;GO:0051583//dopamine uptake involved in synaptic transmission;GO:0002866//positive regulation of acute inflammatory response to antigenic stimulus;GO:1902177//positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:0018323//enzyme active site formation via L-cysteine sulfinic acid;GO:0006914//autophagy;GO:0070301//cellular response to hydrogen peroxide;GO:1903427//negative regulation of reactive oxygen species biosynthetic process;GO:1903189//glyoxal metabolic process;GO:0042743//hydrogen peroxide metabolic process;GO:0007005//mitochondrion organization;GO:0060081//membrane hyperpolarization;GO:0050787//detoxification of mercury ion;GO:2000277//positive regulation of oxidative phosphorylation uncoupler activity;GO:1903384//negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0036471//cellular response to glyoxal;GO:0051899//membrane depolarization;GO:0050821//protein stabilization;GO:1902236//negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway;GO:0046295//glycolate biosynthetic process","K05687//protein DJ-1 [EC:3.5.1.124]","XP_011904884.1//PREDICTED: protein deglycase DJ-1 isoform X1 [Cercocebus atys]","4;1//3"]
[152007,1862,3.21,3.45,0.104023064543228,0.916421411655012,"*",0.861404,"GLIPR2","GO:0070062//extracellular exosome;GO:0005576//extracellular region;GO:0000139//Golgi membrane","GO:0042803//protein homodimerization activity","GO:0010634//positive regulation of epithelial cell migration;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0010718//positive regulation of epithelial to mesenchymal transition","K19919//cysteine-rich secretory protein;K20674//modular serine protease [EC:3.4.21.-];K19867//LIM domain-binding protein 3;K21596//calmodulin-binding transcription activator","NP_001273943.1//Golgi-associated plant pathogenesis-related protein 1 isoform f [Homo sapiens];NP_001273942.1//Golgi-associated plant pathogenesis-related protein 1 isoform e [Homo sapiens];EAW58315.1//chromosome 9 open reading frame 19, isoform CRA_a, partial [Homo sapiens]","1//3;3//A2MP1"]
[27173,2231,90.5,97.23,0.103483729181067,0.0298484078666667,"*",0.01177194,"SLC39A1","GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane","GO:0022890//inorganic cation transmembrane transporter activity;GO:0005102//receptor binding;GO:0005385//zinc ion transmembrane transporter activity","GO:0048701//embryonic cranial skeleton morphogenesis;GO:0060173//limb development;GO:0001701//in utero embryonic development;GO:0006812//cation transport;GO:0071577//zinc II ion transmembrane transport","K14709//solute carrier family 39 (zinc transporter), member 1/2/3","BAG56898.1//unnamed protein product [Homo sapiens];XP_003259388.1//PREDICTED: zinc transporter ZIP1 isoform X1 [Nomascus leucogenys]","4;1//3"]
[2051,3449,0.54,0.58,0.103093492964103,0.933112579978814,"*",0.882292,"EPHB6","GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0005829//cytosol;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0005524//ATP binding;GO:0004872//receptor activity;GO:0005003//ephrin receptor activity","GO:0001806//type IV hypersensitivity;GO:2000525//positive regulation of T cell costimulation;GO:0050663//cytokine secretion;GO:0050798//activated T cell proliferation;GO:0048013//ephrin receptor signaling pathway;GO:0032092//positive regulation of protein binding","K05114//Eph receptor B6 [EC:2.7.10.1]","NP_004436.4//ephrin type-B receptor 6 isoform a precursor [Homo sapiens]","2//1;5"]
[6697,1466,85.28,91.57,0.102667584458207,0.0846058884604792,"*",0.038463,"SPR","GO:0070062//extracellular exosome;GO:0005654//nucleoplasm;GO:0005829//cytosol","GO:0050661//NADP binding;GO:0004033//aldo-keto reductase (NADP) activity;GO:0004757//sepiapterin reductase activity","GO:0050999//regulation of nitric-oxide synthase activity;GO:0006729//tetrahydrobiopterin biosynthetic process;GO:0055114//oxidation-reduction process;GO:0006809//nitric oxide biosynthetic process","K00072//sepiapterin reductase [EC:1.1.1.153]","NP_003115.1//sepiapterin reductase [Homo sapiens]",4]
[57787,5165,5.99,6.43,0.102262734539162,0.462262870893105,"*",0.31268,"MARK4","GO:0036064//ciliary basal body;GO:0005815//microtubule organizing center;GO:0015630//microtubule cytoskeleton;GO:0005829//cytosol;GO:0005813//centrosome;GO:0043005//neuron projection","GO:0043130//ubiquitin binding;GO:0050321//tau-protein kinase activity;GO:0043015//gamma-tubulin binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0008017//microtubule binding","GO:0007399//nervous system development;GO:0000226//microtubule cytoskeleton organization;GO:0006468//protein phosphorylation;GO:0030010//establishment of cell polarity;GO:0097711//ciliary basal body-plasma membrane docking;GO:0051301//cell division;GO:0007049//cell cycle;GO:0001578//microtubule bundle formation;GO:0043068//positive regulation of programmed cell death","K08798//MAP/microtubule affinity-regulating kinase [EC:2.7.11.1]","NP_113605.2//MAP/microtubule affinity-regulating kinase 4 isoform 2 [Homo sapiens];NP_001186796.1//MAP/microtubule affinity-regulating kinase 4 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[9894,3334,15.24,16.35,0.101427732892123,0.310683589948263,"*",0.1842046,"TELO2","GO:0016020//membrane;GO:0005634//nucleus;GO:0000781//chromosome, telomeric region;GO:0005622//intracellular;GO:0005737//cytoplasm;GO:0031931//TORC1 complex;GO:0031932//TORC2 complex;GO:0034399//nuclear periphery;GO:0005829//cytosol;GO:0016604//nuclear body","GO:0032947//protein complex scaffold activity;GO:0051879//Hsp90 protein binding;GO:0019901//protein kinase binding;GO:0032403//protein complex binding","GO:1904263//positive regulation of TORC1 signaling;GO:0032006//regulation of TOR signaling;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0050821//protein stabilization;GO:1904515//positive regulation of TORC2 signaling","K11137//telomere length regulation protein","NP_057195.2//telomere length regulation protein TEL2 homolog [Homo sapiens]","1//3;3//A2MP1"]
[90441,1710,11.74,12.59,0.100845874608964,0.57247600275767,"*",0.415864,"ZNF622","GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0022625//cytosolic large ribosomal subunit;GO:0030687//preribosome, large subunit precursor","GO:0003723//RNA binding;GO:0008270//zinc ion binding;GO:0003676//nucleic acid binding","GO:0046330//positive regulation of JNK cascade;GO:0043065//positive regulation of apoptotic process;GO:0008631//intrinsic apoptotic signaling pathway in response to oxidative stress;GO:0033674//positive regulation of kinase activity;GO:0042273//ribosomal large subunit biogenesis","K14816//pre-60S factor REI1","XP_006165305.1//PREDICTED: zinc finger protein 622 [Tupaia chinensis]","2//1"]
[100528021,2282,5.56,5.96,0.100227447738654,0.653981506506342,"*",0.497098,"ST20-MTHFS","GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005737//cytoplasm","GO:0005542//folic acid binding;GO:0046872//metal ion binding;GO:0005524//ATP binding;GO:0030272//5-formyltetrahydrofolate cyclo-ligase activity","GO:0006536//glutamate metabolic process;GO:0015942//formate metabolic process;GO:0046657//folic acid catabolic process;GO:0046653//tetrahydrofolate metabolic process;GO:0035999//tetrahydrofolate interconversion;GO:0009396//folic acid-containing compound biosynthetic process;GO:0046655//folic acid metabolic process","K01934//5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2]","NP_001186689.1//ST20-MTHFS protein [Homo sapiens]","1//3"]
[6647,981,157.9,169.21,0.0998036604044963,0.0602921659930716,"*",0.026149,"SOD1","GO:0005615//extracellular space;GO:0031410//cytoplasmic vesicle;GO:0005777//peroxisome;GO:0005737//cytoplasm;GO:0043025//neuronal cell body;GO:0005829//cytosol;GO:0031045//dense core granule;GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0070062//extracellular exosome;GO:0031012//extracellular matrix;GO:1904115//axon cytoplasm;GO:0032839//dendrite cytoplasm;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005758//mitochondrial intermembrane space;GO:0043209//myelin sheath;GO:0005764//lysosome;GO:0043234//protein complex","GO:0004784//superoxide dismutase activity;GO:0048365//Rac GTPase binding;GO:0030346//protein phosphatase 2B binding;GO:0042802//identical protein binding;GO:0005507//copper ion binding;GO:0008270//zinc ion binding;GO:0051087//chaperone binding;GO:0042803//protein homodimerization activity","GO:0006801//superoxide metabolic process;GO:0045859//regulation of protein kinase activity;GO:0008217//regulation of blood pressure;GO:0032930//positive regulation of superoxide anion generation;GO:0006879//cellular iron ion homeostasis;GO:0000303//response to superoxide;GO:0060087//relaxation of vascular smooth muscle;GO:0001819//positive regulation of cytokine production;GO:0002262//myeloid cell homeostasis;GO:0097332//response to antipsychotic drug;GO:0045471//response to ethanol;GO:0007566//embryo implantation;GO:0046677//response to antibiotic;GO:0006302//double-strand break repair;GO:0008090//retrograde axonal transport;GO:0035865//cellular response to potassium ion;GO:0071276//cellular response to cadmium ion;GO:0006309//apoptotic DNA fragmentation;GO:0019430//removal of superoxide radicals;GO:0042493//response to drug;GO:0043524//negative regulation of neuron apoptotic process;GO:0072593//reactive oxygen species metabolic process;GO:0009408//response to heat;GO:0001541//ovarian follicle development;GO:0001975//response to amphetamine;GO:0006749//glutathione metabolic process;GO:0060047//heart contraction;GO:0008089//anterograde axonal transport;GO:0060052//neurofilament cytoskeleton organization;GO:0060088//auditory receptor cell stereocilium organization;GO:0019226//transmission of nerve impulse;GO:0040014//regulation of multicellular organism growth;GO:0034465//response to carbon monoxide;GO:0007283//spermatogenesis;GO:0032287//peripheral nervous system myelin maintenance;GO:1902177//positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:0071318//cellular response to ATP;GO:0010033//response to organic substance;GO:0042554//superoxide anion generation;GO:0043085//positive regulation of catalytic activity;GO:0000187//activation of MAPK activity;GO:0007569//cell aging;GO:0048678//response to axon injury;GO:0001895//retina homeostasis;GO:0046688//response to copper ion;GO:0042542//response to hydrogen peroxide;GO:0007568//aging;GO:0046716//muscle cell cellular homeostasis;GO:0045541//negative regulation of cholesterol biosynthetic process;GO:0007626//locomotory behavior;GO:0043087//regulation of GTPase activity;GO:0031667//response to nutrient levels;GO:0007605//sensory perception of sound;GO:0050665//hydrogen peroxide biosynthetic process;GO:0051881//regulation of mitochondrial membrane potential","K04565//superoxide dismutase, Cu-Zn family [EC:1.15.1.1]","NP_000445.1//superoxide dismutase [Cu-Zn] [Homo sapiens]",4]
[284434,8420,0.42,0.45,0.0995356735509144,0.827634539053295,"*",0.747586,"NWD1","GO:0005829//cytosol;GO:0005682//U5 snRNP;GO:0071011//precatalytic spliceosome;GO:0071013//catalytic step 2 spliceosome","GO:0003723//RNA binding;GO:0005524//ATP binding","GO:0008380//RNA splicing","K11127//telomerase protein component 1;K01064//wingless-type MMTV integration site family, member 9","XP_011526231.1//PREDICTED: NACHT domain- and WD repeat-containing protein 1 isoform X1 [Homo sapiens];NP_001007526.3//NACHT domain- and WD repeat-containing protein 1 isoform 1 [Homo sapiens]","4;1//3;2//1"]
[5700,1586,78.62,84.21,0.0990952008095865,0.101361824719101,"*",0.0474384,"PSMC1","GO:0016020//membrane;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005838//proteasome regulatory particle","GO:0003723//RNA binding;GO:0005524//ATP binding;GO:0036402//proteasome-activating ATPase activity","GO:1901215//negative regulation of neuron death;GO:0030163//protein catabolic process","K03062//26S proteasome regulatory subunit T2","XP_021100874.1//26S protease regulatory subunit 4 [Heterocephalus glaber];EHB02601.1//26S protease regulatory subunit 4, partial [Heterocephalus glaber]","1//3;2//1"]
[100288687,1710,2.69,2.88,0.0984626388856881,0.795538772550956,"*",0.706144,"DUX4","NA","NA","NA","K06237//collagen, type IV, alpha;K16628//collagen, type VII, alpha","SBT59247.1//hypothetical protein POVWA2_093830 [Plasmodium ovale wallikeri];ACN62210.1//DUX4 [Homo sapiens]","2//1"]
[60681,2888,66.24,70.91,0.0982864233594171,0.032921039086072,"*",0.01316924,"FKBP10","GO:0005788//endoplasmic reticulum lumen;GO:0005730//nucleolus;GO:0005737//cytoplasm","GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005509//calcium ion binding;GO:0005528//FK506 binding","GO:0000412//histone peptidyl-prolyl isomerization;GO:0061077//chaperone-mediated protein folding","K09575//FK506-binding protein 9/10 [EC:5.2.1.8]","CAD97695.1//hypothetical protein, partial [Homo sapiens]","3//A2MP1"]
[5917,2154,57.15,61.15,0.0975990003129085,0.103943277316294,"*",0.0488808,"RARS","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0017101//aminoacyl-tRNA synthetase multienzyme complex","GO:0034618//arginine binding;GO:0004814//arginine-tRNA ligase activity;GO:0005524//ATP binding;GO:0000049//tRNA binding;GO:0045296//cadherin binding","GO:0006418//tRNA aminoacylation for protein translation;GO:0006420//arginyl-tRNA aminoacylation","K01887//arginyl-tRNA synthetase [EC:6.1.1.19]","NP_002878.2//arginine--tRNA ligase, cytoplasmic [Homo sapiens]","3//A2MP1"]
[4711,1068,25.59,27.37,0.09701528732551,0.439259501596244,"*",0.292858,"NDUFB5","GO:0005654//nucleoplasm;GO:0005747//mitochondrial respiratory chain complex I;GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion","GO:0008137//NADH dehydrogenase (ubiquinone) activity","GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0055114//oxidation-reduction process","K03961//NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 5","NP_002483.1//NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial isoform 1 precursor [Homo sapiens];NP_001186887.1//NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial isoform 3 precursor [Homo sapiens];NP_001186886.1//NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[126353,2891,44.84,47.94,0.0964436308437061,0.0969069291571448,"*",0.045129,"MISP","GO:0043231//intracellular membrane-bounded organelle;GO:0005856//cytoskeleton;GO:0005925//focal adhesion;GO:0005938//cell cortex;GO:0005886//plasma membrane","GO:0003779//actin binding","GO:0051301//cell division;GO:0007049//cell cycle","K16519//A-kinase anchor protein 2;K06236//collagen, type I, alpha","NP_775752.1//mitotic interactor and substrate of PLK1 [Homo sapiens]","3//A2MP1"]
[51406,1287,26.56,28.39,0.0961277023774669,0.778235454935622,"*",0.68109,"NOL7","GO:0005730//nucleolus;GO:0005739//mitochondrion","GO:0003723//RNA binding","NA","NA","XP_004432243.2//PREDICTED: nucleolar protein 7 [Ceratotherium simum simum]","4;1//3"]
[5201,1324,61.61,65.84,0.0957998001069448,0.218996975342466,"*",0.1190952,"PFDN1","GO:0016272//prefoldin complex;GO:0005737//cytoplasm","GO:0051082//unfolded protein binding;GO:0003700//DNA binding transcription factor activity;GO:0044183//protein binding involved in protein folding","GO:0007010//cytoskeleton organization;GO:0007049//cell cycle","K09548//prefoldin subunit 1","XP_003477193.2//PREDICTED: prefoldin subunit 1 [Cavia porcellus]",4]
[5001,1955,23.88,25.5,0.0946944104814154,0.379309599598796,"*",0.236742,"ORC5","GO:0000808//origin recognition complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000784//nuclear chromosome, telomeric region;GO:0005664//nuclear origin of replication recognition complex;GO:0005829//cytosol","GO:0003688//DNA replication origin binding;GO:0005524//ATP binding;GO:0000166//nucleotide binding","GO:0006260//DNA replication;GO:0000082//G1/S transition of mitotic cell cycle;GO:0006270//DNA replication initiation","K02607//origin recognition complex subunit 5","NP_859531.1//origin recognition complex subunit 5 isoform 2 [Homo sapiens];NP_002544.1//origin recognition complex subunit 5 isoform 1 [Homo sapiens]","3//A2MP1"]
[114822,3795,9.03,9.64,0.0943071587491036,0.468150427438687,"*",0.317864,"RHPN1","GO:0005829//cytosol","NA","GO:0007165//signal transduction","K18040//tyrosine-protein phosphatase non-receptor type 23 [EC:3.1.3.48]","NP_443156.2//rhophilin-1 [Homo sapiens]","2//1"]
[221491,972,37.05,39.54,0.0938393285360119,0.5859995324631,"*",0.42998,"SMIM29","GO:0005576//extracellular region","NA","NA","NA","NP_001008703.1//uncharacterized protein SMIM29 isoform 1 precursor [Homo sapiens]","1//3;4;2//1"]
[51205,1862,8.04,8.57,0.0920997029335713,0.712207912317328,"*",0.59798,"ACP6","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion;GO:0005737//cytoplasm","GO:0052642//lysophosphatidic acid phosphatase activity;GO:0003993//acid phosphatase activity","GO:0002244//hematopoietic progenitor cell differentiation;GO:2001311//lysobisphosphatidic acid metabolic process;GO:0006644//phospholipid metabolic process;GO:0006654//phosphatidic acid biosynthetic process","K14395//lysophosphatidic acid phosphatase type 6 [EC:3.1.3.2]","NP_057445.4//lysophosphatidic acid phosphatase type 6 isoform 1 [Homo sapiens];NP_001310554.1//lysophosphatidic acid phosphatase type 6 isoform 2 [Homo sapiens]","4;1//3"]
[4257,923,692.07,737.69,0.0920967110185441,0.000265728595119497,"*",{"v":6.61244e-05,"d":"6.61E-05"},"MGST1","GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005741//mitochondrial outer membrane;GO:0035577//azurophil granule membrane;GO:0016021//integral component of membrane;GO:0045177//apical part of cell;GO:0005789//endoplasmic reticulum membrane;GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0005778//peroxisomal membrane","GO:0004364//glutathione transferase activity;GO:0043295//glutathione binding;GO:0004602//glutathione peroxidase activity;GO:0016740//transferase activity;GO:0042803//protein homodimerization activity","GO:0042493//response to drug;GO:0010243//response to organonitrogen compound;GO:0006805//xenobiotic metabolic process;GO:0032496//response to lipopolysaccharide;GO:0055114//oxidation-reduction process;GO:0071449//cellular response to lipid hydroperoxide;GO:0033327//Leydig cell differentiation;GO:0043312//neutrophil degranulation;GO:1901687//glutathione derivative biosynthetic process;GO:0070207//protein homotrimerization","K00799//glutathione S-transferase [EC:2.5.1.18]","NP_001254527.1//microsomal glutathione S-transferase 1 isoform c [Homo sapiens];EAW96364.1//microsomal glutathione S-transferase 1, isoform CRA_c [Homo sapiens];XP_009001524.1//PREDICTED: microsomal glutathione S-transferase 1 isoform X1 [Callithrix jacchus]","1//3;4;2//1"]
[28512,2013,5.18,5.52,0.091716169091615,0.689110621896929,"*",0.571728,"NKIRAS1","GO:0016020//membrane;GO:0005737//cytoplasm","GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0007165//signal transduction;GO:0007249//I-kappaB kinase/NF-kappaB signaling","K17197//NF-kappa-B inhibitor-interacting Ras-like protein","XP_015316384.1//PREDICTED: NF-kappa-B inhibitor-interacting Ras-like protein 1 isoform X1 [Bos taurus]","3//A2MP1"]
[79885,2833,3.25,3.46,0.0903323197209076,0.857402977188909,"*",0.785908,"HDAC11","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0000118//histone deacetylase complex;GO:0005886//plasma membrane","GO:0004407//histone deacetylase activity;GO:0016787//hydrolase activity;GO:0032041//NAD-dependent histone deacetylase activity (H3-K14 specific);GO:0008134//transcription factor binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006325//chromatin organization;GO:0014003//oligodendrocyte development;GO:0006351//transcription, DNA-templated;GO:0016575//histone deacetylation","K11418//histone deacetylase 11 [EC:3.5.1.98]","XP_018880133.1//PREDICTED: histone deacetylase 11 isoform X1 [Gorilla gorilla gorilla];XP_017820599.1//PREDICTED: histone deacetylase 11 isoform X2 [Callithrix jacchus];XP_009236662.1//PREDICTED: histone deacetylase 11 isoform X1 [Pongo abelii]","1//3;3//A2MP1;2//1"]
[55696,2352,28.84,30.7,0.0901674910167192,0.299855824850299,"*",0.175551,"RBM22","GO:0071007//U2-type catalytic step 2 spliceosome;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0071006//U2-type catalytic step 1 spliceosome;GO:0000974//Prp19 complex;GO:0005737//cytoplasm;GO:0071013//catalytic step 2 spliceosome;GO:0005681//spliceosomal complex","GO:0003723//RNA binding;GO:0036002//pre-mRNA binding;GO:0046872//metal ion binding;GO:0005487//nucleocytoplasmic transporter activity;GO:0048306//calcium-dependent protein binding;GO:0017070//U6 snRNA binding","GO:0033120//positive regulation of RNA splicing;GO:0000398//mRNA splicing, via spliceosome;GO:0035690//cellular response to drug;GO:0090316//positive regulation of intracellular protein transport;GO:0000060//protein import into nucleus, translocation;GO:0045292//mRNA cis splicing, via spliceosome;GO:0000387//spliceosomal snRNP assembly","K12872//pre-mRNA-splicing factor RBM22/SLT11","XP_005380625.1//PREDICTED: pre-mRNA-splicing factor RBM22 [Chinchilla lanigera]","2//1"]
[30850,3546,35.7,37.98,0.0893158312330351,0.134467454770318,"*",0.0667034,"CDR2L","NA","NA","NA","K16628//collagen, type VII, alpha","NP_055418.2//cerebellar degeneration-related protein 2-like [Homo sapiens]","2//1"]
[116988,3032,27.8,29.56,0.0885613865352811,0.540235029942217,"*",0.386288,"AGAP3","GO:0016020//membrane;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0005096//GTPase activator activity","GO:0007165//signal transduction","K12491//Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1/3","NP_001337033.1//arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 isoform h [Homo sapiens];NP_001036000.1//arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 isoform b [Homo sapiens];NP_001295234.1//arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 isoform e [Homo sapiens];NP_114152.3//arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 isoform a [Homo sapiens];NP_001337032.1//arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 isoform g [Homo sapiens];XP_016801398.1//PREDICTED: arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 isoform X3 [Pan troglodytes];NP_001337031.1//arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 isoform f [Homo sapiens];NP_001295233.1//arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 isoform d [Homo sapiens]","6;1//3;3//A2MP1"]
[1948,4404,0.95,1.01,0.0883558744208469,0.842884479504814,"*",0.767218,"EFNB2","GO:0005887//integral component of plasma membrane;GO:0005925//focal adhesion;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0046875//ephrin receptor binding;GO:0001618//virus receptor activity","GO:0010839//negative regulation of keratinocyte proliferation;GO:0016477//cell migration;GO:0031295//T cell costimulation;GO:0002042//cell migration involved in sprouting angiogenesis;GO:0010977//negative regulation of neuron projection development;GO:0050920//regulation of chemotaxis;GO:0007411//axon guidance;GO:0009653//anatomical structure morphogenesis;GO:0001945//lymph vessel development;GO:0007267//cell-cell signaling;GO:0048013//ephrin receptor signaling pathway;GO:1901216//positive regulation of neuron death;GO:0007155//cell adhesion;GO:0009887//animal organ morphogenesis;GO:1903849//positive regulation of aorta morphogenesis;GO:0048514//blood vessel morphogenesis;GO:2000727//positive regulation of cardiac muscle cell differentiation;GO:0048845//venous blood vessel morphogenesis;GO:0072178//nephric duct morphogenesis;GO:0008284//positive regulation of cell proliferation","K05463//ephrin-B","NP_004084.1//ephrin-B2 precursor [Homo sapiens]","3//A2MP1"]
[2580,4519,15.05,15.99,0.0874064518332675,0.333282599271971,"*",0.200608,"GAK","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005925//focal adhesion;GO:0031982//vesicle;GO:0048471//perinuclear region of cytoplasm;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0045202//synapse","GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0051087//chaperone binding;GO:0030332//cyclin binding","GO:0016191//synaptic vesicle uncoating;GO:0072659//protein localization to plasma membrane;GO:1905224//clathrin-coated pit assembly;GO:0090160//Golgi to lysosome transport;GO:0072583//clathrin-dependent endocytosis;GO:0051085//chaperone cofactor-dependent protein refolding;GO:0007030//Golgi organization;GO:0061024//membrane organization;GO:0072600//establishment of protein localization to Golgi;GO:0010977//negative regulation of neuron projection development;GO:0006898//receptor-mediated endocytosis;GO:0072318//clathrin coat disassembly;GO:0007049//cell cycle;GO:0007029//endoplasmic reticulum organization","K08855//cyclin G-associated kinase [EC:2.7.11.1]","NP_005246.2//cyclin-G-associated kinase isoform 1 [Homo sapiens];NP_001305063.1//cyclin-G-associated kinase isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[26959,2764,8.06,8.56,0.0868309578731796,0.646414621293467,"*",0.48993,"HBP1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016607//nuclear speck","GO:0003723//RNA binding;GO:0003677//DNA binding","GO:0006355//regulation of transcription, DNA-templated;GO:0016055//Wnt signaling pathway;GO:0006351//transcription, DNA-templated;GO:0007050//cell cycle arrest","K21644//HMG box transcription factor 1","XP_004635043.1//PREDICTED: HMG box-containing protein 1 isoform X1 [Octodon degus];XP_009452138.1//PREDICTED: HMG box-containing protein 1 isoform X1 [Pan troglodytes]","1//3;3//A2MP1"]
[2990,2319,15.58,16.54,0.0862640011096054,0.516433493099122,"*",0.360734,"GUSB","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005764//lysosome;GO:0035578//azurophil granule lumen;GO:0005576//extracellular region;GO:1904813//ficolin-1-rich granule lumen;GO:0043202//lysosomal lumen","GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0019904//protein domain specific binding;GO:0005102//receptor binding;GO:0004566//beta-glucuronidase activity","GO:0043312//neutrophil degranulation;GO:0030214//hyaluronan catabolic process;GO:0005975//carbohydrate metabolic process;GO:0006027//glycosaminoglycan catabolic process","K01195//beta-glucuronidase [EC:3.2.1.31]","NP_001280033.1//beta-glucuronidase isoform 3 [Homo sapiens];NP_001271219.1//beta-glucuronidase isoform 2 precursor [Homo sapiens];NP_000172.2//beta-glucuronidase isoform 1 precursor [Homo sapiens];NP_001280034.1//beta-glucuronidase isoform 4 [Homo sapiens]","1//3;3//A2MP1"]
[79629,1166,8.06,8.55,0.0851445812452928,0.741016046724226,"*",0.639378,"OCEL1","NA","NA","NA","K04942//potassium intermediate/small conductance calcium-activated channel subfamily N member 1;K17291//MARVEL domain-containing protein 2","XP_014198046.1//PREDICTED: occludin/ELL domain-containing protein 1 isoform X1 [Pan paniscus]","2//1"]
[8669,2523,28.47,30.19,0.0846282637713598,0.395431264332137,"*",0.255196,"EIF3J","GO:0016282//eukaryotic 43S preinitiation complex;GO:0005829//cytosol;GO:0033290//eukaryotic 48S preinitiation complex;GO:0005852//eukaryotic translation initiation factor 3 complex","GO:0003743//translation initiation factor activity","GO:0006413//translational initiation;GO:0006446//regulation of translational initiation;GO:0001731//formation of translation preinitiation complex","K03245//translation initiation factor 3 subunit J","XP_006883010.1//PREDICTED: eukaryotic translation initiation factor 3 subunit J-A-like [Elephantulus edwardii];NP_001271265.1//eukaryotic translation initiation factor 3 subunit J isoform 3 [Homo sapiens];XP_007962947.1//PREDICTED: eukaryotic translation initiation factor 3 subunit J [Chlorocebus sabaeus]","1//3;3//A2MP1"]
[23508,5217,0.83,0.88,0.0843921872903726,0.846275120945574,"*",0.77094,"TTC9","NA","NA","NA","K19475//WAS/WASL-interacting protein;K05746//enabled;K20638//Rho GTPase-activating protein 17","XP_012359753.1//PREDICTED: tetratricopeptide repeat protein 9A [Nomascus leucogenys]","1//3"]
[91368,1270,38.36,40.65,0.0836526319442592,0.450465012865933,"*",0.302472,"CDKN2AIPNL","GO:0005654//nucleoplasm;GO:0005730//nucleolus","NA","GO:0007165//signal transduction","K12581//CCR4-NOT transcription complex subunit 7/8;K17985//activating molecule in BECN1-regulated autophagy protein 1","XP_022349178.1//LOW QUALITY PROTEIN: CDKN2AIP N-terminal-like protein [Enhydra lutris kenyoni]","2//1"]
[10775,2612,25.15,26.64,0.0830356823783728,0.356822792445125,"*",0.218798,"POP4","GO:0000172//ribonuclease MRP complex;GO:0005654//nucleoplasm;GO:0030681//multimeric ribonuclease P complex;GO:0030677//ribonuclease P complex;GO:0005655//nucleolar ribonuclease P complex","GO:0033204//ribonuclease P RNA binding;GO:0003723//RNA binding;GO:0004526//ribonuclease P activity","GO:0006379//mRNA cleavage;GO:0001682//tRNA 5'-leader removal;GO:0006364//rRNA processing;GO:0008033//tRNA processing","K03538//ribonuclease P protein subunit POP4 [EC:3.1.26.5]","NP_006618.1//ribonuclease P protein subunit p29 [Homo sapiens]","2//1"]
[55735,3316,28.29,29.96,0.0827454470624984,0.251275507277151,"*",0.1422332,"DNAJC11","GO:0070062//extracellular exosome;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0001401//mitochondrial sorting and assembly machinery complex;GO:0061617//MICOS complex","NA","GO:0042407//cristae formation","K09531//DnaJ homolog subfamily C member 11","NP_060668.2//dnaJ homolog subfamily C member 11 [Homo sapiens]","3//A2MP1"]
[4953,2147,78.81,83.44,0.0823604566649776,0.207060722065837,"*",0.1114374,"ODC1","GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm","GO:0004586//ornithine decarboxylase activity;GO:0003824//catalytic activity;GO:0042803//protein homodimerization activity","GO:0006595//polyamine metabolic process;GO:0001822//kidney development;GO:0006521//regulation of cellular amino acid metabolic process;GO:0006596//polyamine biosynthetic process;GO:0042176//regulation of protein catabolic process;GO:0009615//response to virus;GO:0008284//positive regulation of cell proliferation;GO:0033387//putrescine biosynthetic process from ornithine","K01581//ornithine decarboxylase [EC:4.1.1.17]","XP_017506692.1//PREDICTED: ornithine decarboxylase [Manis javanica];NP_002530.1//ornithine decarboxylase isoform 1 [Homo sapiens]","1//3;2//1"]
[5423,1351,7.16,7.58,0.0822382609068354,0.745519650687907,"*",0.644524,"POLB","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005874//microtubule;GO:0043234//protein complex;GO:0005737//cytoplasm;GO:0005876//spindle microtubule","GO:0003677//DNA binding;GO:0003906//DNA-(apurinic or apyrimidinic site) lyase activity;GO:0008017//microtubule binding;GO:0003887//DNA-directed DNA polymerase activity;GO:0016829//lyase activity;GO:0046872//metal ion binding;GO:0003684//damaged DNA binding;GO:0019899//enzyme binding","GO:0051402//neuron apoptotic process;GO:0006284//base-excision repair;GO:0016446//somatic hypermutation of immunoglobulin genes;GO:0010332//response to gamma radiation;GO:0045471//response to ethanol;GO:0048536//spleen development;GO:0006288//base-excision repair, DNA ligation;GO:0016579//protein deubiquitination;GO:0006974//cellular response to DNA damage stimulus;GO:0048872//homeostasis of number of cells;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0006281//DNA repair;GO:0071707//immunoglobulin heavy chain V-D-J recombination;GO:0048535//lymph node development;GO:0006287//base-excision repair, gap-filling;GO:0007568//aging;GO:0006954//inflammatory response;GO:0007435//salivary gland morphogenesis;GO:0055093//response to hyperoxia;GO:0006261//DNA-dependent DNA replication;GO:0006286//base-excision repair, base-free sugar-phosphate removal;GO:0006290//pyrimidine dimer repair","K02330//DNA polymerase beta [EC:2.7.7.7 4.2.99.-]","NP_002681.1//DNA polymerase beta [Homo sapiens]","2//1"]
[9156,3218,9.78,10.35,0.081724397434454,0.656549155691836,"*",0.536164,"EXO1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body","GO:0003677//DNA binding;GO:0004523//RNA-DNA hybrid ribonuclease activity;GO:0045145//single-stranded DNA 5'-3' exodeoxyribonuclease activity;GO:0008409//5'-3' exonuclease activity;GO:0051908//double-stranded DNA 5'-3' exodeoxyribonuclease activity;GO:0004527//exonuclease activity;GO:0046872//metal ion binding;GO:0048256//flap endonuclease activity;GO:0003682//chromatin binding;GO:0035312//5'-3' exodeoxyribonuclease activity","GO:0045190//isotype switching;GO:0000732//strand displacement;GO:0006281//DNA repair;GO:0016446//somatic hypermutation of immunoglobulin genes;GO:0006298//mismatch repair;GO:0006260//DNA replication;GO:0090656//t-circle formation;GO:1901796//regulation of signal transduction by p53 class mediator;GO:0000731//DNA synthesis involved in DNA repair;GO:0051321//meiotic cell cycle;GO:0006310//DNA recombination;GO:0002455//humoral immune response mediated by circulating immunoglobulin","K10746//exonuclease 1 [EC:3.1.-.-]","NP_001306153.1//exonuclease 1 isoform c [Homo sapiens];NP_006018.4//exonuclease 1 isoform b [Homo sapiens];NP_003677.4//exonuclease 1 isoform a [Homo sapiens]","4;1//3;3//A2MP1"]
[150159,1755,1.56,1.65,0.0809199953835675,0.873622415954416,"*",0.806244,"SLC9B1","GO:0097228//sperm principal piece;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005886//plasma membrane","GO:0015385//sodium:proton antiporter activity;GO:0015299//solute:proton antiporter activity","GO:0030317//flagellated sperm motility;GO:0034220//ion transmembrane transport;GO:0007338//single fertilization;GO:0051453//regulation of intracellular pH;GO:0006814//sodium ion transport","K16816//patatin-like phospholipase domain-containing protein 2 [EC:3.1.1.3]","XP_016806465.1//PREDICTED: sodium/hydrogen exchanger 9B1 isoform X1 [Pan troglodytes]","3//A2MP1;2//1"]
[57099,1551,11,11.63,0.0803475730611966,0.66985375486618,"*",0.551516,"AVEN","GO:0016020//membrane;GO:0012505//endomembrane system;GO:0005622//intracellular","NA","GO:0043066//negative regulation of apoptotic process;GO:0006915//apoptotic process","K19475//WAS/WASL-interacting protein;K13199//plasminogen activator inhibitor 1 RNA-binding protein;K14958//kinase suppressor of Ras 1","NP_065104.1//cell death regulator Aven [Homo sapiens]","2//1"]
[81621,2677,2.46,2.6,0.0798533076892146,0.78859118846317,"*",0.698348,"KAZALD1","GO:0005614//interstitial matrix","GO:0005520//insulin-like growth factor binding","GO:0001558//regulation of cell growth;GO:0030154//cell differentiation;GO:0007275//multicellular organism development;GO:0030198//extracellular matrix organization;GO:0001503//ossification","K08784//HtrA serine peptidase 1 [EC:3.4.21.-]","NP_112191.2//kazal-type serine protease inhibitor domain-containing protein 1 isoform a precursor [Homo sapiens];AAG50291.1//FKSG40 [Homo sapiens]","4;1//3"]
[23207,4167,19.49,20.59,0.0792097393743644,0.319941519488416,"*",0.1910556,"PLEKHM2","GO:0010008//endosome membrane","GO:0019894//kinesin binding","GO:0032880//regulation of protein localization;GO:1903527//positive regulation of membrane tubulation;GO:0007030//Golgi organization;GO:0032418//lysosome localization","K15348//pleckstrin homology domain-containing family M member 2","AAH40441.1//PLEKHM2 protein, partial [Homo sapiens]","3//A2MP1"]
[493753,1767,7.34,7.75,0.0784162473183871,0.72280005943978,"*",0.609,"COA5","GO:0005739//mitochondrion","NA","GO:0033617//mitochondrial respiratory chain complex IV assembly","K18178//cytochrome c oxidase assembly factor 5","NP_001008216.1//cytochrome c oxidase assembly factor 5 [Homo sapiens]","2//1"]
[9401,3840,24.69,26.05,0.0773565360230885,0.28843860919367,"*",0.1677292,"RECQL4","GO:0016020//membrane;GO:0005634//nucleus;GO:0000781//chromosome, telomeric region;GO:0005737//cytoplasm","GO:0000405//bubble DNA binding;GO:0061821//telomeric D-loop binding;GO:0005524//ATP binding;GO:0004386//helicase activity;GO:0036310//annealing helicase activity;GO:0009378//four-way junction helicase activity;GO:0043140//ATP-dependent 3'-5' DNA helicase activity;GO:0032357//oxidized purine DNA binding","GO:0061820//telomeric D-loop disassembly;GO:0006281//DNA repair;GO:0006284//base-excision repair;GO:0007275//multicellular organism development;GO:0000733//DNA strand renaturation;GO:0006260//DNA replication;GO:0000724//double-strand break repair via homologous recombination;GO:0032508//DNA duplex unwinding;GO:0000723//telomere maintenance","K10730//ATP-dependent DNA helicase Q4 [EC:3.6.4.12]","NP_004251.3//ATP-dependent DNA helicase Q4 [Homo sapiens]","3//A2MP1"]
[84916,2215,72.24,76.21,0.0771824225355402,0.152987657901204,"*",0.07794,"UTP4","GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0001650//fibrillar center;GO:0005694//chromosome;GO:0034455//t-UTP complex","GO:0003723//RNA binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006364//rRNA processing;GO:0030490//maturation of SSU-rRNA","K14548//U3 small nucleolar RNA-associated protein 4","XP_017706262.1//PREDICTED: U3 small nucleolar RNA-associated protein 4 homolog [Rhinopithecus bieti]","1//3;2//1"]
[84243,3165,17.42,18.37,0.0766070025124849,0.44391928440367,"*",0.296854,"ZDHHC18","GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane","GO:0016409//palmitoyltransferase activity;GO:0019706//protein-cysteine S-palmitoyltransferase activity","GO:0018345//protein palmitoylation;GO:0034613//cellular protein localization","K16675//palmitoyltransferase ZDHHC9/14/18 [EC:2.3.1.225]","NP_115659.1//palmitoyltransferase ZDHHC18 [Homo sapiens]","2//1"]
[11345,1031,33.74,35.56,0.0757953505422043,0.576023787552724,"*",0.41891,"GABARAPL2","GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0031410//cytoplasmic vesicle;GO:0005622//intracellular;GO:0005737//cytoplasm;GO:0005776//autophagosome;GO:0000139//Golgi membrane;GO:0000421//autophagosome membrane","GO:0000149//SNARE binding;GO:0050811//GABA receptor binding;GO:0048487//beta-tubulin binding;GO:0031625//ubiquitin protein ligase binding;GO:0051117//ATPase binding;GO:0008017//microtubule binding","GO:0006891//intra-Golgi vesicle-mediated transport;GO:0061024//membrane organization;GO:0000422//autophagy of mitochondrion;GO:0097352//autophagosome maturation;GO:0006995//cellular response to nitrogen starvation;GO:0032781//positive regulation of ATPase activity;GO:0006914//autophagy;GO:1901799//negative regulation of proteasomal protein catabolic process;GO:0000045//autophagosome assembly;GO:0015031//protein transport;GO:0016236//macroautophagy","K08341//GABA(A) receptor-associated protein","XP_010382367.1//PREDICTED: uncharacterized protein LOC104678726 [Rhinopithecus roxellana]",6]
[143884,3285,1.86,1.96,0.0755510330071768,0.822855642574464,"*",0.74193,"CWF19L2","NA","NA","NA","K21436//ankyrin repeat domain-containing protein 11/12;K13172//serine/arginine repetitive matrix protein 2;K00476//aspartate beta-hydroxylase [EC:1.14.11.16]","NP_689647.2//CWF19-like protein 2 [Homo sapiens]","2//1"]
[23617,1832,0.75,0.79,0.0749620576812222,0.91817318322237,"*",0.863338,"TSSK2","NA","NA","NA","K08811//testis-specific serine kinase [EC:2.7.11.1]","XP_008964883.1//PREDICTED: testis-specific serine/threonine-protein kinase 2 isoform X1 [Pan paniscus]",4]
[7517,2596,24.14,25.42,0.0745383542499374,0.390551963328351,"*",0.245348,"XRCC3","GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0033063//Rad51B-Rad51C-Rad51D-XRCC2 complex;GO:0005657//replication fork;GO:0033065//Rad51C-XRCC3 complex;GO:0048471//perinuclear region of cytoplasm","GO:0003697//single-stranded DNA binding;GO:0000150//recombinase activity;GO:0005524//ATP binding;GO:0008094//DNA-dependent ATPase activity;GO:0003690//double-stranded DNA binding;GO:0000400//four-way junction DNA binding;GO:0008821//crossover junction endodeoxyribonuclease activity","GO:0000722//telomere maintenance via recombination;GO:0010212//response to ionizing radiation;GO:0071140//resolution of mitotic recombination intermediates;GO:0090267//positive regulation of mitotic cell cycle spindle assembly checkpoint;GO:0010824//regulation of centrosome duplication;GO:0090656//t-circle formation;GO:0042148//strand invasion;GO:0007131//reciprocal meiotic recombination;GO:0000707//meiotic DNA recombinase assembly;GO:0006312//mitotic recombination;GO:0036297//interstrand cross-link repair","K10880//DNA-repair protein XRCC3","XP_011806812.1//PREDICTED: DNA repair protein XRCC3 [Colobus angolensis palliatus]","1//3;3//A2MP1"]
[29941,3404,16.95,17.84,0.0738303418965986,0.483910337657592,"*",0.331594,"PKN3","NA","NA","NA","K06071//protein kinase N [EC:2.7.11.13]","XP_017354656.1//PREDICTED: serine/threonine-protein kinase N3 isoform X4 [Cebus capucinus imitator];XP_008974290.1//PREDICTED: serine/threonine-protein kinase N3 [Pan paniscus]","1//3;4"]
[5794,3394,1.53,1.61,0.073529035421965,0.81771412687813,"*",0.735912,"PTPRH","NA","NA","NA","K18034//receptor-type tyrosine-protein phosphatase H [EC:3.1.3.48]","NP_001154912.2//receptor-type tyrosine-protein phosphatase H isoform 2 precursor [Homo sapiens];NP_002833.4//receptor-type tyrosine-protein phosphatase H isoform 1 precursor [Homo sapiens]","4;2//1"]
[4664,3994,5.78,6.08,0.0730018309429066,0.763134811681772,"*",0.664148,"NAB1","GO:0005634//nucleus","GO:0008134//transcription factor binding","GO:0014037//Schwann cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0042552//myelination;GO:0001958//endochondral ossification;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0045682//regulation of epidermis development","NA","XP_017708399.1//PREDICTED: NGFI-A-binding protein 1 isoform X2 [Rhinopithecus bieti];XP_017708398.1//PREDICTED: NGFI-A-binding protein 1 isoform X1 [Rhinopithecus bieti];XP_011791828.1//PREDICTED: NGFI-A-binding protein 1 isoform X5 [Colobus angolensis palliatus]","1//3;3//A2MP1"]
[317662,3149,2.91,3.06,0.072512499784368,0.780113148187709,"*",0.68581,"FAM149B1","NA","NA","NA","NA","BAA76818.1//KIAA0974 protein, partial [Homo sapiens]","1//3"]
[322,2671,10.24,10.76,0.0714623625566241,0.642384982049797,"*",0.486152,"APBB1","GO:0005737//cytoplasm;GO:0043025//neuronal cell body;GO:0030426//growth cone;GO:0042734//presynaptic membrane;GO:0043197//dendritic spine;GO:0045202//synapse;GO:0005886//plasma membrane;GO:0045211//postsynaptic membrane;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:1990761//growth cone lamellipodium;GO:0044304//main axon;GO:0016607//nuclear speck;GO:0030027//lamellipodium;GO:0048471//perinuclear region of cytoplasm;GO:1990812//growth cone filopodium;GO:0043234//protein complex","GO:0042393//histone binding;GO:0001540//amyloid-beta binding;GO:0003682//chromatin binding;GO:0008134//transcription factor binding;GO:0070064//proline-rich region binding;GO:0048156//tau protein binding;GO:0032403//protein complex binding","GO:0006355//regulation of transcription, DNA-templated;GO:0007050//cell cycle arrest;GO:0045893//positive regulation of transcription, DNA-templated;GO:0050760//negative regulation of thymidylate synthase biosynthetic process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006302//double-strand break repair;GO:0043065//positive regulation of apoptotic process;GO:0043967//histone H4 acetylation;GO:0045739//positive regulation of DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0030308//negative regulation of cell growth;GO:0007165//signal transduction;GO:0006351//transcription, DNA-templated;GO:0010976//positive regulation of neuron projection development;GO:0010039//response to iron ion;GO:0006915//apoptotic process;GO:0007409//axonogenesis;GO:0050714//positive regulation of protein secretion;GO:0045944//positive regulation of transcription from RNA polymerase II promoter","K04529//amyloid beta A4 precursor protein-binding family B member 1","XP_011827902.1//PREDICTED: amyloid beta A4 precursor protein-binding family B member 1 isoform X6 [Mandrillus leucophaeus];XP_011809696.1//PREDICTED: amyloid beta A4 precursor protein-binding family B member 1 isoform X2 [Colobus angolensis palliatus];XP_006718278.3//PREDICTED: amyloid beta A4 precursor protein-binding family B member 1 isoform X5 [Homo sapiens];XP_011809697.1//PREDICTED: amyloid beta A4 precursor protein-binding family B member 1 isoform X3 [Colobus angolensis palliatus];CAD98057.1//hypothetical protein, partial [Homo sapiens];XP_004279296.1//PREDICTED: amyloid beta A4 precursor protein-binding family B member 1 isoform X4 [Orcinus orca]","4;2//1"]
[55585,3223,34,35.72,0.0711973340961587,0.293524734692126,"*",0.1712932,"UBE2Q1","GO:0005634//nucleus;GO:0005829//cytosol;GO:0030175//filopodium","GO:0005524//ATP binding;GO:0061631//ubiquitin conjugating enzyme activity","GO:0007617//mating behavior;GO:0009566//fertilization;GO:0001967//suckling behavior;GO:0061458//reproductive system development;GO:0070459//prolactin secretion;GO:0007566//embryo implantation","K10582//ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]","XP_014445213.1//PREDICTED: ubiquitin-conjugating enzyme E2 Q1 [Tupaia chinensis]",6]
[84304,1021,22.59,23.72,0.0704197391529191,0.443888742696629,"*",0.296778,"NUDT22","GO:0005654//nucleoplasm","GO:0016787//hydrolase activity","NA","NA","EAW74208.1//nudix (nucleoside diphosphate linked moiety X)-type motif 22, isoform CRA_e [Homo sapiens];XP_012351909.1//PREDICTED: nucleoside diphosphate-linked moiety X motif 22 isoform X3 [Nomascus leucogenys];EAW74209.1//nudix (nucleoside diphosphate linked moiety X)-type motif 22, isoform CRA_f [Homo sapiens];XP_018891721.1//PREDICTED: nucleoside diphosphate-linked moiety X motif 22 isoform X1 [Gorilla gorilla gorilla]","1//3;3//A2MP1;2//1"]
[219287,9953,0.4,0.42,0.0703893278913977,0.83746885399449,"*",0.76124,"AMER2","GO:0005886//plasma membrane","GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0008013//beta-catenin binding","GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0060828//regulation of canonical Wnt signaling pathway;GO:0016055//Wnt signaling pathway;GO:0048856//anatomical structure development;GO:0007398//ectoderm development","K19407//APC membrane recruitment protein 1","NP_954589.1//APC membrane recruitment protein 2 isoform 2 [Homo sapiens];NP_689917.2//APC membrane recruitment protein 2 isoform 1 [Homo sapiens]","3//A2MP1;2//1"]
[84936,2035,7.68,8.06,0.0696735278068113,0.718351338240761,"*",0.604802,"ZFYVE19","GO:0032154//cleavage furrow;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0030496//midbody","GO:0046872//metal ion binding;GO:0032266//phosphatidylinositol-3-phosphate binding","GO:0044878//mitotic cytokinesis checkpoint;GO:0051301//cell division;GO:0009838//abscission;GO:0032466//negative regulation of cytokinesis","K09537//DnaJ homolog subfamily C member 17;K12182//hepatocyte growth factor-regulated tyrosine kinase substrate","NP_116239.3//abscission/NoCut checkpoint regulator isoform 3 [Homo sapiens];NP_001245349.1//abscission/NoCut checkpoint regulator isoform 2 [Homo sapiens];NP_001070736.1//abscission/NoCut checkpoint regulator isoform 1 [Homo sapiens]","4;1//3"]
[8804,2048,71.46,74.97,0.06917748822259,0.226451169875986,"*",0.1257432,"CREG1","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0035578//azurophil granule lumen;GO:0005667//transcription factor complex;GO:0005576//extracellular region","GO:0003714//transcription corepressor activity;GO:0048037//cofactor binding;GO:0008134//transcription factor binding","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0006355//regulation of transcription, DNA-templated;GO:0040008//regulation of growth;GO:0007275//multicellular organism development;GO:0043312//neutrophil degranulation","NA","NP_003842.1//protein CREG1 precursor [Homo sapiens]","2//1"]
[79177,1863,15.56,16.32,0.0687989969853036,0.636354724023211,"*",0.514892,"ZNF576","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","NP_077303.1//zinc finger protein 576 [Homo sapiens]","1//3;2//1"]
[50486,978,1.85,1.94,0.0685313816708155,0.929824506896552,"*",0.877786,"G0S2","GO:0005811//lipid droplet;GO:0016021//integral component of membrane;GO:0005739//mitochondrion","NA","GO:0097191//extrinsic apoptotic signaling pathway;GO:0019216//regulation of lipid metabolic process;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway","K10262//F-box and WD-40 domain protein 4;K13221//methylosome protein 50;K17776//metaxin","NP_056529.1//G0/G1 switch protein 2 [Homo sapiens]","3//A2MP1"]
[1939,2115,23.69,24.83,0.0678060629366095,0.536788108165057,"*",0.382748,"EIF2D","GO:0016604//nuclear body;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0003743//translation initiation factor activity;GO:0004872//receptor activity","GO:0006886//intracellular protein transport;GO:0075522//IRES-dependent viral translational initiation;GO:0032790//ribosome disassembly;GO:0001731//formation of translation preinitiation complex","K15027//translation initiation factor 2D","NP_008824.2//eukaryotic translation initiation factor 2D isoform 1 [Homo sapiens];NP_001188407.1//eukaryotic translation initiation factor 2D isoform 2 [Homo sapiens]","1//3;2//1"]
[143241,787,8.75,9.17,0.0676387168753633,0.828857123337029,"*",0.748846,"DYDC1","GO:0048188//Set1C/COMPASS complex;GO:0000781//chromosome, telomeric region","NA","GO:0051568//histone H3-K4 methylation;GO:0006348//chromatin silencing at telomere","K18626//trichohyalin;K03681//exosome complex component RRP40","NP_620167.1//DPY30 domain-containing protein 1 [Homo sapiens]","1//3;3//A2MP1"]
[4605,2756,88.84,93.07,0.0671068143620178,0.134728980570275,"*",0.06685,"MYBL2","GO:0031523//Myb complex;GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0003677//DNA binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0001135//transcription factor activity, RNA polymerase II transcription factor recruiting","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0043525//positive regulation of neuron apoptotic process;GO:1990830//cellular response to leukemia inhibitory factor;GO:0090307//mitotic spindle assembly;GO:0030154//cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0051726//regulation of cell cycle","K21769//myb-related protein B","NP_002457.1//myb-related protein B isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[23403,3084,13.6,14.24,0.0663424948286961,0.802782581662093,"*",0.714182,"FBXO46","NA","NA","NA","K10320//F-box protein 46","XP_010375767.1//PREDICTED: LOW QUALITY PROTEIN: F-box only protein 46 [Rhinopithecus roxellana]","1//3"]
[51497,2320,34.62,36.24,0.0659772306795965,0.425476837297812,"*",0.27994,"NELFCD","GO:0016020//membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0032021//NELF complex","GO:0003723//RNA binding","GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0045892//negative regulation of transcription, DNA-templated;GO:0050434//positive regulation of viral transcription;GO:0006366//transcription from RNA polymerase II promoter","K15181//negative elongation factor C/D","NP_945327.2//negative elongation factor C/D [Homo sapiens]","2//1"]
[84236,5052,3.89,4.07,0.0652586392800551,0.769527595666834,"*",0.671494,"RHBDD1","GO:0005783//endoplasmic reticulum;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005739//mitochondrion;GO:0005789//endoplasmic reticulum membrane;GO:0044322//endoplasmic reticulum quality control compartment","GO:0004252//serine-type endopeptidase activity;GO:0004175//endopeptidase activity","GO:0043687//post-translational protein modification;GO:0010954//positive regulation of protein processing;GO:0034620//cellular response to unfolded protein;GO:0043066//negative regulation of apoptotic process;GO:0006915//apoptotic process;GO:0034644//cellular response to UV;GO:0048515//spermatid differentiation;GO:0036503//ERAD pathway;GO:0045732//positive regulation of protein catabolic process;GO:0033619//membrane protein proteolysis;GO:0031293//membrane protein intracellular domain proteolysis;GO:1904211//membrane protein proteolysis involved in retrograde protein transport, ER to cytosol;GO:0051047//positive regulation of secretion","K09651//rhomboid domain-containing protein 1 [EC:3.4.21.-]","NP_115652.2//rhomboid-related protein 4 [Homo sapiens]","1//3;4;2//1"]
[91782,2807,24.35,25.46,0.0643106469316534,0.64869889354679,"*",0.492108,"CHMP7","GO:0005634//nucleus;GO:0000785//chromatin;GO:0005635//nuclear envelope;GO:0005829//cytosol;GO:0005622//intracellular;GO:0000815//ESCRT III complex","GO:0008565//protein transporter activity","GO:0016197//endosomal transport;GO:0006997//nucleus organization;GO:0071168//protein localization to chromatin;GO:0007034//vacuolar transport;GO:0045324//late endosome to vacuole transport;GO:0019058//viral life cycle;GO:0039702//viral budding via host ESCRT complex;GO:1904903//ESCRT III complex disassembly;GO:0036258//multivesicular body assembly;GO:0000920//cell separation after cytokinesis;GO:0007080//mitotic metaphase plate congression;GO:0010458//exit from mitosis;GO:0031468//nuclear envelope reassembly","K15053//charged multivesicular body protein 7","XP_017405228.1//PREDICTED: charged multivesicular body protein 7 [Cebus capucinus imitator];XP_021570945.1//charged multivesicular body protein 7 isoform X2 [Carlito syrichta]","4;1//3"]
[6352,1237,30.15,31.52,0.0641095326689292,0.677191502312533,"*",0.559126,"CCL5","GO:0005615//extracellular space;GO:0005622//intracellular;GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0004435//phosphatidylinositol phospholipase C activity;GO:0046817//chemokine receptor antagonist activity;GO:0043621//protein self-association;GO:0031726//CCR1 chemokine receptor binding;GO:0042803//protein homodimerization activity;GO:0031729//CCR4 chemokine receptor binding;GO:0004672//protein kinase activity;GO:0031730//CCR5 chemokine receptor binding;GO:0016004//phospholipase activator activity;GO:0008009//chemokine activity;GO:0030298//receptor signaling protein tyrosine kinase activator activity;GO:0042056//chemoattractant activity","GO:0010820//positive regulation of T cell chemotaxis;GO:0007159//leukocyte cell-cell adhesion;GO:0042102//positive regulation of T cell proliferation;GO:0043491//protein kinase B signaling;GO:0071356//cellular response to tumor necrosis factor;GO:0050796//regulation of insulin secretion;GO:0033634//positive regulation of cell-cell adhesion mediated by integrin;GO:0071346//cellular response to interferon-gamma;GO:0071347//cellular response to interleukin-1;GO:0043922//negative regulation by host of viral transcription;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0070234//positive regulation of T cell apoptotic process;GO:0048245//eosinophil chemotaxis;GO:0090026//positive regulation of monocyte chemotaxis;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0070098//chemokine-mediated signaling pathway;GO:0051262//protein tetramerization;GO:0031584//activation of phospholipase D activity;GO:0006816//calcium ion transport;GO:0034612//response to tumor necrosis factor;GO:1901214//regulation of neuron death;GO:0051928//positive regulation of calcium ion transport;GO:0043623//cellular protein complex assembly;GO:0010759//positive regulation of macrophage chemotaxis;GO:0045744//negative regulation of G-protein coupled receptor protein signaling pathway;GO:2000110//negative regulation of macrophage apoptotic process;GO:0009636//response to toxic substance;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0071407//cellular response to organic cyclic compound;GO:0045071//negative regulation of viral genome replication;GO:0070233//negative regulation of T cell apoptotic process;GO:0006874//cellular calcium ion homeostasis;GO:0014911//positive regulation of smooth muscle cell migration;GO:0007186//G-protein coupled receptor signaling pathway;GO:2000503//positive regulation of natural killer cell chemotaxis;GO:0000165//MAPK cascade;GO:0034112//positive regulation of homotypic cell-cell adhesion;GO:0042119//neutrophil activation;GO:0007267//cell-cell signaling;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0006954//inflammatory response;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0006955//immune response;GO:0031328//positive regulation of cellular biosynthetic process;GO:0009615//response to virus;GO:0050679//positive regulation of epithelial cell proliferation;GO:0006887//exocytosis","K12499//C-C motif chemokine 5","NP_001265665.1//C-C motif chemokine 5 isoform 2 precursor [Homo sapiens];XP_008009272.1//PREDICTED: C-C motif chemokine 5 [Chlorocebus sabaeus]","1//3;2//1"]
[64785,2235,14.4,15.05,0.0636946753173896,0.562238887369059,"*",0.406562,"GINS3","GO:0005634//nucleus;GO:0005654//nucleoplasm","NA","GO:0006260//DNA replication;GO:0006271//DNA strand elongation involved in DNA replication","K10734//GINS complex subunit 3","EPY84737.1//DNA replication complex GINS protein PSF3 isoform c [Camelus ferus];XP_008538624.1//PREDICTED: DNA replication complex GINS protein PSF3 [Equus przewalskii];NP_001119601.1//DNA replication complex GINS protein PSF3 isoform a [Homo sapiens]","1//3;3//A2MP1"]
[57794,2116,12.84,13.41,0.0626640347821708,0.670157625114017,"*",0.551934,"SUGP1","GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex","GO:0003723//RNA binding","GO:0006396//RNA processing;GO:0000398//mRNA splicing, via spliceosome","K13096//splicing factor 4","NP_757386.2//SURP and G-patch domain-containing protein 1 [Homo sapiens]","3//A2MP1"]
[6941,3219,11.27,11.77,0.0626268048662231,0.884211495648654,"*",0.8205,"TCF19","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003700//DNA binding transcription factor activity","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0006351//transcription, DNA-templated","K11446//histone demethylase JARID1 [EC:1.14.11.-]","NP_001070979.1//transcription factor 19 [Homo sapiens]","1//3;2//1"]
[79917,2654,1.16,1.21,0.0608822421470224,0.95002688672799,"*",0.905184,"MAGIX","NA","NA","NA","K06237//collagen, type IV, alpha;K05631//atrophin-1 interacting protein 3 (BAI1-associated protein 1);K22020//mucin-19;K05629//atrophin-1 interacting protein 1","NP_001093152.2//PDZ domain-containing protein MAGIX isoform d [Homo sapiens];NP_001093151.2//PDZ domain-containing protein MAGIX isoform c [Homo sapiens];NP_079135.3//PDZ domain-containing protein MAGIX isoform a [Homo sapiens]","3//A2MP1;2//1"]
[64285,3091,10.07,10.5,0.0603256445467004,0.650532799507995,"*",0.529744,"RHBDF1","GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0000139//Golgi membrane","GO:0004252//serine-type endopeptidase activity;GO:0019838//growth factor binding","GO:0016477//cell migration;GO:0006508//proteolysis;GO:0050709//negative regulation of protein secretion;GO:0008283//cell proliferation;GO:0042058//regulation of epidermal growth factor receptor signaling pathway;GO:0050708//regulation of protein secretion;GO:0015031//protein transport;GO:0061136//regulation of proteasomal protein catabolic process","K21125//mucin-5AC","NP_071895.3//inactive rhomboid protein 1 [Homo sapiens]","3//A2MP1"]
[149840,1418,9.46,9.86,0.0597474630385161,0.638666097463948,"*",0.482418,"C20orf196","NA","NA","NA","K19991//chromogranin-B","XP_004061828.1//PREDICTED: uncharacterized protein C20orf196 isoform X1 [Gorilla gorilla gorilla];XP_012365710.1//PREDICTED: uncharacterized protein C20orf196 homolog isoform X3 [Nomascus leucogenys];XP_011527479.1//PREDICTED: uncharacterized protein C20orf196 isoform X1 [Homo sapiens];XP_011527482.1//PREDICTED: uncharacterized protein C20orf196 isoform X6 [Homo sapiens]","1//3;3//A2MP1"]
[85463,8807,0.96,1,0.0588936890535686,0.810731637814009,"*",0.725314,"ZC3H12C","NA","GO:0046872//metal ion binding","NA","K18668//ribonuclease ZC3H12 [EC:3.1.-.-]","XP_009422404.1//PREDICTED: probable ribonuclease ZC3H12C isoform X3 [Pan troglodytes]","1//3"]
[9138,3236,44.95,46.81,0.0584956493101446,0.367448731161102,"*",0.228028,"ARHGEF1","GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity","GO:0007266//Rho protein signal transduction;GO:0043065//positive regulation of apoptotic process;GO:0008283//cell proliferation;GO:0050771//negative regulation of axonogenesis;GO:0035023//regulation of Rho protein signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction","K12330//Rho guanine nucleotide exchange factor 1","NP_945353.1//rho guanine nucleotide exchange factor 1 isoform 1 [Homo sapiens];XP_008963082.1//PREDICTED: rho guanine nucleotide exchange factor 1 isoform X5 [Pan paniscus]","1//3;3//A2MP1"]
[51634,1861,12.66,13.18,0.0580729655797105,0.720970551616499,"*",0.607278,"RBMX2","GO:0005686//U2 snRNP;GO:0071011//precatalytic spliceosome;GO:0070274//RES complex;GO:0071013//catalytic step 2 spliceosome","GO:0003723//RNA binding","GO:0006406//mRNA export from nucleus;GO:0000398//mRNA splicing, via spliceosome","K13107//RNA-binding motif protein, X-linked 2","NP_057108.2//RNA-binding motif protein, X-linked 2 [Homo sapiens]","3//A2MP1"]
[7059,3251,3.92,4.08,0.0577154978562874,0.650100422042567,"*",0.493334,"THBS3","GO:0005576//extracellular region;GO:0048471//perinuclear region of cytoplasm","GO:0005509//calcium ion binding;GO:0008201//heparin binding","GO:0007160//cell-matrix adhesion;GO:0007155//cell adhesion;GO:0003417//growth plate cartilage development;GO:0060346//bone trabecula formation;GO:0043931//ossification involved in bone maturation","K04659//thrombospondin 2/3/4/5","NP_001239537.1//thrombospondin-3 isoform 3 precursor [Homo sapiens];NP_001239536.1//thrombospondin-3 isoform 2 precursor [Homo sapiens];NP_009043.1//thrombospondin-3 isoform 1 precursor [Homo sapiens]","4;1//3"]
[56945,1155,29.53,30.73,0.0574664104590079,0.661430614561028,"*",0.541434,"MRPS22","GO:0005840//ribosome;GO:0005761//mitochondrial ribosome;GO:0005763//mitochondrial small ribosomal subunit;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0003735//structural constituent of ribosome","GO:0070126//mitochondrial translational termination;GO:0070125//mitochondrial translational elongation","K17401//small subunit ribosomal protein S22","NP_064576.1//28S ribosomal protein S22, mitochondrial [Homo sapiens]","2//1"]
[4795,1473,8.93,9.29,0.05701842126143,0.749347251049052,"*",0.648396,"NFKBIL1","GO:0005634//nucleus;GO:0005829//cytosol","NA","GO:0042994//cytoplasmic sequestering of transcription factor;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0031665//negative regulation of lipopolysaccharide-mediated signaling pathway;GO:0071222//cellular response to lipopolysaccharide;GO:0032720//negative regulation of tumor necrosis factor production;GO:0034122//negative regulation of toll-like receptor signaling pathway;GO:0032088//negative regulation of NF-kappaB transcription factor activity","K09256//NF-kappa-B inhibitor-like protein 1","XP_011855843.1//PREDICTED: NF-kappa-B inhibitor-like protein 1 isoform X1 [Mandrillus leucophaeus];XP_011855844.1//PREDICTED: NF-kappa-B inhibitor-like protein 1 isoform X2 [Mandrillus leucophaeus];NP_001138433.1//NF-kappa-B inhibitor-like protein 1 isoform 2 [Homo sapiens];NP_004998.3//NF-kappa-B inhibitor-like protein 1 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[1759,3890,127.86,132.98,0.0566442838359529,0.0134688010975184,"*",4.82462E-3,"DNM1","GO:0070062//extracellular exosome;GO:0001917//photoreceptor inner segment;GO:0005874//microtubule;GO:0008021//synaptic vesicle;GO:0043209//myelin sheath;GO:0043196//varicosity;GO:0030117//membrane coat;GO:0005794//Golgi apparatus;GO:0031966//mitochondrial membrane;GO:0045202//synapse;GO:0005886//plasma membrane","GO:0003723//RNA binding;GO:0042802//identical protein binding;GO:0008017//microtubule binding;GO:0019901//protein kinase binding;GO:0046983//protein dimerization activity;GO:0003924//GTPase activity;GO:0050998//nitric-oxide synthase binding;GO:0031749//D2 dopamine receptor binding;GO:0008022//protein C-terminus binding;GO:0005525//GTP binding;GO:0032403//protein complex binding","GO:0072583//clathrin-dependent endocytosis;GO:0048013//ephrin receptor signaling pathway;GO:0008344//adult locomotory behavior;GO:0051262//protein tetramerization;GO:0016185//synaptic vesicle budding from presynaptic endocytic zone membrane;GO:0003374//dynamin family protein polymerization involved in mitochondrial fission;GO:0051932//synaptic transmission, GABAergic;GO:0061025//membrane fusion;GO:1901998//toxin transport;GO:0007605//sensory perception of sound;GO:0006898//receptor-mediated endocytosis;GO:0006897//endocytosis;GO:0007032//endosome organization;GO:0002031//G-protein coupled receptor internalization;GO:0000266//mitochondrial fission;GO:1903423//positive regulation of synaptic vesicle recycling","K01528//dynamin GTPase [EC:3.6.5.5]","NP_004399.2//dynamin-1 isoform 1 [Homo sapiens];NP_001005336.1//dynamin-1 isoform 2 [Homo sapiens];BAD90284.1//mKIAA4093 protein, partial [Mus musculus];NP_001275668.1//dynamin-1 isoform 4 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[55324,2570,15.03,15.63,0.0564727690833001,0.665608903422517,"*",0.546646,"ABCF3","NA","NA","NA","K06158//ATP-binding cassette, subfamily F, member 3","NP_001338228.1//ATP-binding cassette sub-family F member 3 isoform 3 [Homo sapiens];XP_007195384.1//PREDICTED: ATP-binding cassette sub-family F member 3 [Balaenoptera acutorostrata scammoni]","1//3;2//1"]
[51434,2728,27.54,28.63,0.0559991108643888,0.358839623931624,"*",0.220776,"ANAPC7","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005680//anaphase-promoting complex","GO:0019903//protein phosphatase binding","GO:0070979//protein K11-linked ubiquitination;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0051301//cell division;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle","K03354//anaphase-promoting complex subunit 7","NP_057322.2//anaphase-promoting complex subunit 7 isoform a [Homo sapiens];NP_001131136.1//anaphase-promoting complex subunit 7 isoform b [Homo sapiens]","1//3;2//1"]
[8216,4332,10.94,11.37,0.0556195160996913,0.627246443407234,"*",0.471122,"LZTR1","GO:0005794//Golgi apparatus","GO:0003700//DNA binding transcription factor activity","GO:0009653//anatomical structure morphogenesis","K14966//host cell factor;K20285//Rab9 effector protein with kelch motifs","NP_006758.2//leucine-zipper-like transcriptional regulator 1 [Homo sapiens]","3//A2MP1"]
[202243,3511,4.64,4.82,0.0549083411023897,0.805215784384004,"*",0.717254,"CCDC125","GO:0005737//cytoplasm","NA","GO:0090630//activation of GTPase activity;GO:2000146//negative regulation of cell motility;GO:2000145//regulation of cell motility;GO:0035024//negative regulation of Rho protein signal transduction","K05765//cofilin;K17985//activating molecule in BECN1-regulated autophagy protein 1;K06662//cell cycle checkpoint protein","NP_001284625.1//coiled-coil domain-containing protein 125 isoform 2 [Homo sapiens];XP_005248516.1//PREDICTED: coiled-coil domain-containing protein 125 isoform X2 [Homo sapiens];EAW51298.1//Kenae, isoform CRA_a, partial [Homo sapiens]","4;1//3"]
[1892,1350,74.71,77.58,0.0543834139145738,0.465929962333826,"*",0.315948,"ECHS1","GO:0005759//mitochondrial matrix;GO:0070062//extracellular exosome;GO:0005739//mitochondrion","GO:0003824//catalytic activity;GO:0004300//enoyl-CoA hydratase activity","GO:0006635//fatty acid beta-oxidation;GO:0008152//metabolic process","K07511//enoyl-CoA hydratase [EC:4.2.1.17]","NP_004083.3//enoyl-CoA hydratase, mitochondrial [Homo sapiens]","3//A2MP1"]
[93323,1468,8.63,8.96,0.054138172878649,0.81143705697446,"*",0.723964,"HAUS8","GO:0000922//spindle pole;GO:0005874//microtubule;GO:0070652//HAUS complex;GO:0005829//cytosol;GO:0005813//centrosome","NA","GO:0010389//regulation of G2/M transition of mitotic cell cycle;GO:0097711//ciliary basal body-plasma membrane docking;GO:0007098//centrosome cycle;GO:0051225//spindle assembly;GO:0051301//cell division;GO:0000086//G2/M transition of mitotic cell cycle","K16591//HAUS augmin-like complex subunit 8","NP_219485.1//HAUS augmin-like complex subunit 8 isoform a [Homo sapiens];NP_001011699.1//HAUS augmin-like complex subunit 8 isoform b [Homo sapiens]","1//3"]
[5641,2185,33.22,34.48,0.0537077011267218,0.560776936325045,"*",0.405224,"LGMN","GO:0070062//extracellular exosome;GO:0005770//late endosome;GO:0043202//lysosomal lumen;GO:0005764//lysosome;GO:0045177//apical part of cell;GO:0036021//endolysosome lumen","GO:0008233//peptidase activity;GO:0004197//cysteine-type endopeptidase activity","GO:0032801//receptor catabolic process;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0043524//negative regulation of neuron apoptotic process;GO:0002224//toll-like receptor signaling pathway;GO:1901185//negative regulation of ERBB signaling pathway;GO:0003014//renal system process;GO:0006508//proteolysis;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0010447//response to acidic pH;GO:0006624//vacuolar protein processing;GO:0040015//negative regulation of multicellular organism growth;GO:0042359//vitamin D metabolic process","K01369//legumain [EC:3.4.22.34]","NP_005597.3//legumain preproprotein [Homo sapiens]","6;2//1"]
[57509,4085,57.81,59.99,0.0534029591532266,0.000550504539585297,"*",0.000146259,"MTUS1","GO:0005815//microtubule organizing center;GO:0005615//extracellular space;GO:0005730//nucleolus;GO:0005874//microtubule;GO:0015630//microtubule cytoskeleton;GO:0005794//Golgi apparatus;GO:0005819//spindle;GO:0005739//mitochondrion;GO:0005886//plasma membrane","NA","NA","K10352//myosin heavy chain;K21954//FYVE and coiled-coil domain-containing protein 1;K20283//golgin subfamily A member 4;K18626//trichohyalin;K20478//golgin subfamily B member 1","NP_001001924.1//microtubule-associated tumor suppressor 1 isoform 1 [Homo sapiens];NP_001001925.1//microtubule-associated tumor suppressor 1 isoform 2 [Homo sapiens];NP_001317399.1//microtubule-associated tumor suppressor 1 isoform 7 [Homo sapiens];NP_001001931.1//microtubule-associated tumor suppressor 1 isoform 4 [Homo sapiens];NP_065800.1//microtubule-associated tumor suppressor 1 isoform 5 [Homo sapiens]","1//3;4;2//1"]
[50813,2003,44.24,45.89,0.0528284211775653,0.695511881033055,"*",0.578258,"COPS7A","NA","NA","NA","K12180//COP9 signalosome complex subunit 7","XP_019609974.1//PREDICTED: COP9 signalosome complex subunit 7a isoform X1 [Rhinolophus sinicus];XP_011364134.1//PREDICTED: COP9 signalosome complex subunit 7a isoform X1 [Pteropus vampyrus]","1//3;3//A2MP1;2//1"]
[2671,2447,17.54,18.19,0.0524967952067534,0.645437708651105,"*",0.524504,"GFER","GO:0005829//cytosol;GO:0005758//mitochondrial intermembrane space;GO:0005576//extracellular region;GO:0005739//mitochondrion","GO:0015035//protein disulfide oxidoreductase activity;GO:0008083//growth factor activity;GO:0016971//flavin-linked sulfhydryl oxidase activity;GO:0050660//flavin adenine dinucleotide binding;GO:0016972//thiol oxidase activity","GO:0001889//liver development","K17783//mitochondrial FAD-linked sulfhydryl oxidase [EC:1.8.3.2]","EAW85579.1//growth factor, augmenter of liver regeneration (ERV1 homolog, S. cerevisiae), isoform CRA_b, partial [Homo sapiens]","2//1"]
[117177,9287,1.92,1.99,0.0516621198224926,0.813493545454546,"*",0.730484,"RAB3IP","GO:0005856//cytoskeleton;GO:0036064//ciliary basal body;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005813//centrosome;GO:0030027//lamellipodium","GO:0042802//identical protein binding;GO:0017112//Rab guanyl-nucleotide exchange factor activity","GO:0006612//protein targeting to membrane;GO:0060271//cilium assembly;GO:0097711//ciliary basal body-plasma membrane docking;GO:0033365//protein localization to organelle;GO:0061024//membrane organization;GO:0006893//Golgi to plasma membrane transport","K16779//Rab-3A-interacting protein","NP_783322.1//rab-3A-interacting protein isoform alpha 2 [Homo sapiens];XP_006719290.3//PREDICTED: rab-3A-interacting protein isoform X3 [Homo sapiens];XP_018894075.1//PREDICTED: rab-3A-interacting protein isoform X1 [Gorilla gorilla gorilla];NP_783324.1//rab-3A-interacting protein isoform beta 2 [Homo sapiens]","1//3;4;3//A2MP1"]
[54978,3912,41.99,43.51,0.0513012287055122,0.362153006192265,"*",0.223336,"SLC35F6","GO:0005765//lysosomal membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005739//mitochondrion","NA","GO:1901029//negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway;GO:0008284//positive regulation of cell proliferation","K15696//RING finger protein 113B;K00772//5'-methylthioadenosine phosphorylase [EC:2.4.2.28]","XP_012643642.1//solute carrier family 35 member F6 [Microcebus murinus]","3//A2MP1"]
[26088,3184,15.39,15.94,0.0506583976622613,0.633083650756694,"*",0.476616,"GGA1","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0010008//endosome membrane;GO:0005654//nucleoplasm;GO:0030131//clathrin adaptor complex;GO:0031901//early endosome membrane;GO:0005794//Golgi apparatus;GO:0043234//protein complex","GO:0030306//ADP-ribosylation factor binding;GO:0046982//protein heterodimerization activity","GO:0006886//intracellular protein transport;GO:0044267//cellular protein metabolic process;GO:1901998//toxin transport;GO:0045732//positive regulation of protein catabolic process;GO:0016192//vesicle-mediated transport;GO:0061024//membrane organization","K12404//ADP-ribosylation factor-binding protein GGA","NP_037497.1//ADP-ribosylation factor-binding protein GGA1 isoform 1 [Homo sapiens];NP_001166158.1//ADP-ribosylation factor-binding protein GGA1 isoform 4 [Homo sapiens];NP_001001560.1//ADP-ribosylation factor-binding protein GGA1 isoform 2 [Homo sapiens]","1//3;4;2//1"]
[10551,996,23.4,24.23,0.0502858749805797,0.759892847262248,"*",0.66028,"AGR2","GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005739//mitochondrion","GO:0005154//epidermal growth factor receptor binding;GO:0002162//dystroglycan binding;GO:0042803//protein homodimerization activity","GO:1903899//positive regulation of PERK-mediated unfolded protein response;GO:0030154//cell differentiation;GO:0048639//positive regulation of developmental growth;GO:0010628//positive regulation of gene expression;GO:0048546//digestive tract morphogenesis;GO:0060480//lung goblet cell differentiation;GO:0070254//mucus secretion;GO:1903078//positive regulation of protein localization to plasma membrane;GO:0060548//negative regulation of cell death;GO:0045742//positive regulation of epidermal growth factor receptor signaling pathway;GO:0010811//positive regulation of cell-substrate adhesion;GO:1903896//positive regulation of IRE1-mediated unfolded protein response","K20356//anterior gradient protein 2","AAY84773.1//AGR2 [Homo sapiens]","3//A2MP1"]
[7307,978,64.35,66.6,0.0495820288505604,0.639599009344351,"*",0.518478,"U2AF1","GO:0005654//nucleoplasm;GO:0089701//U2AF;GO:0005681//spliceosomal complex;GO:0016607//nuclear speck;GO:0015030//Cajal body;GO:0071013//catalytic step 2 spliceosome","GO:0050733//RS domain binding;GO:0003723//RNA binding;GO:0046872//metal ion binding;GO:0030628//pre-mRNA 3'-splice site binding","GO:0006397//mRNA processing;GO:0006406//mRNA export from nucleus;GO:0000398//mRNA splicing, via spliceosome;GO:1903955//positive regulation of protein targeting to mitochondrion;GO:0006369//termination of RNA polymerase II transcription;GO:1903146//regulation of autophagy of mitochondrion;GO:0031124//mRNA 3'-end processing;GO:0006405//RNA export from nucleus;GO:0008380//RNA splicing","K12836//splicing factor U2AF 35 kDa subunit","NP_006749.1//splicing factor U2AF 35 kDa subunit isoform a [Homo sapiens];XP_004092375.1//PREDICTED: splicing factor U2AF 35 kDa subunit isoform X2 [Nomascus leucogenys];NP_001020374.1//splicing factor U2AF 35 kDa subunit isoform b [Homo sapiens]","1//3;2//1"]
[124454,3965,14.77,15.28,0.0489747172709595,0.63596330040674,"*",0.47962,"EARS2","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0050561//glutamate-tRNA(Gln) ligase activity;GO:0005524//ATP binding;GO:0008270//zinc ion binding;GO:0000049//tRNA binding;GO:0004818//glutamate-tRNA ligase activity","GO:0070127//tRNA aminoacylation for mitochondrial protein translation;GO:0006424//glutamyl-tRNA aminoacylation","K01885//glutamyl-tRNA synthetase [EC:6.1.1.17]","NP_001295140.1//probable glutamate--tRNA ligase, mitochondrial isoform 2 [Homo sapiens];NP_001077083.1//probable glutamate--tRNA ligase, mitochondrial isoform 1 [Homo sapiens]","1//3"]
[8607,1906,50.97,52.72,0.0487020171026752,0.765045258268622,"*",0.666098,"RUVBL1","GO:0000812//Swr1 complex;GO:0035267//NuA4 histone acetyltransferase complex;GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005815//microtubule organizing center;GO:0031011//Ino80 complex;GO:0016363//nuclear matrix;GO:0071339//MLL1 complex;GO:0043234//protein complex;GO:0005829//cytosol;GO:0030529//intracellular ribonucleoprotein complex;GO:0097255//R2TP complex","GO:0005524//ATP binding;GO:0051117//ATPase binding;GO:0045296//cadherin binding;GO:0004003//ATP-dependent DNA helicase activity;GO:0043531//ADP binding;GO:0043140//ATP-dependent 3'-5' DNA helicase activity;GO:0043141//ATP-dependent 5'-3' DNA helicase activity;GO:0003678//DNA helicase activity;GO:0016887//ATPase activity;GO:0001094//TFIID-class transcription factor binding","GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0040008//regulation of growth;GO:1903955//positive regulation of protein targeting to mitochondrion;GO:0043968//histone H2A acetylation;GO:0007283//spermatogenesis;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0043967//histone H4 acetylation;GO:0016579//protein deubiquitination;GO:0006281//DNA repair;GO:0016573//histone acetylation;GO:0006351//transcription, DNA-templated;GO:1903146//regulation of autophagy of mitochondrion;GO:2000269//regulation of fibroblast apoptotic process;GO:0000492//box C/D snoRNP assembly;GO:1904837//beta-catenin-TCF complex assembly;GO:1904874//positive regulation of telomerase RNA localization to Cajal body;GO:0051301//cell division;GO:0034080//CENP-A containing nucleosome assembly;GO:0010756//positive regulation of plasminogen activation;GO:0006310//DNA recombination;GO:0007049//cell cycle","K04499//RuvB-like protein 1 (pontin 52)","OBS67033.1//hypothetical protein A6R68_04429, partial [Neotoma lepida];XP_011511551.1//PREDICTED: ruvB-like 1 isoform X5 [Homo sapiens];XP_022377181.1//ruvB-like 1 isoform X2 [Enhydra lutris kenyoni]","1//3;2//1"]
[6839,2752,25.24,26.1,0.048337896474698,0.609247523028818,"*",0.45131,"SUV39H1","GO:0005652//nuclear lamina;GO:0033553//rDNA heterochromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0000775//chromosome, centromeric region;GO:0000794//condensed nuclear chromosome;GO:0005677//chromatin silencing complex;GO:0000792//heterochromatin","GO:0008757//S-adenosylmethionine-dependent methyltransferase activity;GO:0046974//histone methyltransferase activity (H3-K9 specific);GO:0047485//protein N-terminus binding;GO:0003682//chromatin binding;GO:0008270//zinc ion binding;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0042054//histone methyltransferase activity;GO:0018024//histone-lysine N-methyltransferase activity","GO:0045892//negative regulation of transcription, DNA-templated;GO:0071456//cellular response to hypoxia;GO:0042754//negative regulation of circadian rhythm;GO:0036124//histone H3-K9 trimethylation;GO:0030154//cell differentiation;GO:0006351//transcription, DNA-templated;GO:0016032//viral process;GO:0006364//rRNA processing;GO:0048511//rhythmic process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006325//chromatin organization;GO:0000183//chromatin silencing at rDNA;GO:0036123//histone H3-K9 dimethylation;GO:0007049//cell cycle;GO:0006974//cellular response to DNA damage stimulus","K11419//histone-lysine N-methyltransferase SUV39H [EC:2.1.1.43]","XP_012327085.1//histone-lysine N-methyltransferase SUV39H1 isoform X2 [Aotus nancymaae];NP_001125697.1//histone-lysine N-methyltransferase SUV39H1 [Pongo abelii]","1//3;3//A2MP1"]
[2189,2649,29.49,30.48,0.0476370804315853,0.590388915921288,"*",0.433866,"FANCG","GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0043240//Fanconi anaemia nuclear complex;GO:0005886//plasma membrane","GO:0003684//damaged DNA binding;GO:0004871//signal transducer activity","GO:0006281//DNA repair;GO:0007286//spermatid development;GO:0001541//ovarian follicle development;GO:0007005//mitochondrion organization;GO:0000075//cell cycle checkpoint;GO:0000160//phosphorelay signal transduction system;GO:0009314//response to radiation;GO:0036297//interstrand cross-link repair;GO:0006974//cellular response to DNA damage stimulus","K10894//fanconi anemia group G protein","NP_004620.1//Fanconi anemia group G protein [Homo sapiens]","1//3"]
[388969,4283,11.12,11.49,0.047222009922606,0.664440329285987,"*",0.544688,"C2orf68","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein;K12581//CCR4-NOT transcription complex subunit 7/8;K12900//FUS-interacting serine-arginine-rich protein 1;K01064//wingless-type MMTV integration site family, member 9","NP_001013671.2//UPF0561 protein C2orf68 [Homo sapiens]","3//A2MP1"]
[388886,1240,7.96,8.22,0.0463699631380342,0.858637667007987,"*",0.787416,"LRRC75B","NA","NA","NA","K19719//collagen, type II, alpha;K06236//collagen, type I, alpha;K17446//insulin receptor substrate 4","NP_997527.2//leucine-rich repeat-containing protein 75B [Homo sapiens]","2//1"]
[51247,1498,40.16,41.45,0.0456128324323409,0.63366748413067,"*",0.51244,"PAIP2","GO:0005737//cytoplasm","GO:0003729//mRNA binding;GO:0030371//translation repressor activity","GO:1900271//regulation of long-term synaptic potentiation;GO:0045947//negative regulation of translational initiation;GO:0007613//memory;GO:0007283//spermatogenesis","NA","NP_057564.3//polyadenylate-binding protein-interacting protein 2 [Homo sapiens]","4;2//1"]
[55256,1863,41.69,43.02,0.0453061526146722,1.01831185933504,"*",0.99702,"ADI1","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0010309//acireductone dioxygenase [iron(II)-requiring] activity;GO:0016491//oxidoreductase activity","GO:0019509//L-methionine salvage from methylthioadenosine","K08967//1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase [EC:1.13.11.53 1.13.11.54]","XP_018877019.1//PREDICTED: 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase isoform X1 [Gorilla gorilla gorilla];NP_001293006.1//1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[85416,4657,3.18,3.28,0.0446690493337283,0.824904364973633,"*",0.744242,"ZIC5","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003676//nucleic acid binding","GO:0007399//nervous system development;GO:0030154//cell differentiation","K09226//zinc finger protein ZIC 5","NP_149123.2//zinc finger protein ZIC 5 [Homo sapiens]",4]
[56052,3859,30.01,30.94,0.0440298778507472,0.653505450832886,"*",0.532942,"ALG1","GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0004578//chitobiosyldiphosphodolichol beta-mannosyltransferase activity;GO:0000030//mannosyltransferase activity","GO:0006486//protein glycosylation;GO:0006488//dolichol-linked oligosaccharide biosynthetic process","K03842//beta-1,4-mannosyltransferase [EC:2.4.1.142]","NP_061982.3//chitobiosyldiphosphodolichol beta-mannosyltransferase isoform 1 [Homo sapiens]","1//3;4"]
[954,2156,0.65,0.67,0.0437213774293181,0.918112057253179,"*",0.863338,"ENTPD2","GO:0070062//extracellular exosome;GO:0005605//basal lamina;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane","GO:0005524//ATP binding;GO:0017111//nucleoside-triphosphatase activity;GO:0017110//nucleoside-diphosphatase activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0009181//purine ribonucleoside diphosphate catabolic process;GO:0034656//nucleobase-containing small molecule catabolic process;GO:0030168//platelet activation","K01509//adenosinetriphosphatase [EC:3.6.1.3]","NP_982293.1//ectonucleoside triphosphate diphosphohydrolase 2 isoform 1 [Homo sapiens];NP_001237.1//ectonucleoside triphosphate diphosphohydrolase 2 isoform 2 [Homo sapiens]","3//A2MP1;2//1"]
[8813,1121,34.23,35.27,0.0431802834164143,0.718693429484797,"*",0.60518,"DPM1","GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0033185//dolichol-phosphate-mannose synthase complex;GO:0005789//endoplasmic reticulum membrane","GO:0016757//transferase activity, transferring glycosyl groups;GO:0004582//dolichyl-phosphate beta-D-mannosyltransferase activity;GO:0043178//alcohol binding;GO:0005537//mannose binding;GO:0004169//dolichyl-phosphate-mannose-protein mannosyltransferase activity","GO:0006506//GPI anchor biosynthetic process;GO:0035269//protein O-linked mannosylation;GO:0018279//protein N-linked glycosylation via asparagine;GO:0019348//dolichol metabolic process;GO:0019673//GDP-mannose metabolic process;GO:0035268//protein mannosylation","K00721//dolichol-phosphate mannosyltransferase [EC:2.4.1.83]","NP_001303964.1//dolichol-phosphate mannosyltransferase subunit 1 isoform 2 [Homo sapiens];NP_001303963.1//dolichol-phosphate mannosyltransferase subunit 1 isoform 1 [Homo sapiens];NP_001303965.1//dolichol-phosphate mannosyltransferase subunit 1 isoform 4 [Homo sapiens];XP_018872616.1//PREDICTED: dolichol-phosphate mannosyltransferase subunit 1 [Gorilla gorilla gorilla]","1//3;2//1"]
[91942,719,34.6,35.65,0.0431300388071634,0.787099402604757,"*",0.69614,"NDUFAF2","GO:0016020//membrane;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0009055//electron transfer activity;GO:0008137//NADH dehydrogenase (ubiquinone) activity","GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0061179//negative regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0022904//respiratory electron transport chain;GO:0072593//reactive oxygen species metabolic process;GO:0045333//cellular respiration","K18160//NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2","NP_777549.1//NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 [Homo sapiens]",4]
[124995,1852,63.78,65.7,0.042789272957431,0.544714655488604,"*",0.39048,"MRPL10","GO:0005840//ribosome;GO:0005654//nucleoplasm;GO:0005762//mitochondrial large ribosomal subunit;GO:0030529//intracellular ribonucleoprotein complex;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome","GO:0042254//ribosome biogenesis;GO:0032543//mitochondrial translation;GO:0006412//translation;GO:0070126//mitochondrial translational termination;GO:0070125//mitochondrial translational elongation","K02864//large subunit ribosomal protein L10","NP_683685.1//39S ribosomal protein L10, mitochondrial isoform b [Homo sapiens];XP_003826816.1//PREDICTED: 39S ribosomal protein L10, mitochondrial-like [Pan paniscus]","3//A2MP1;2//1"]
[25851,5752,4.41,4.54,0.0419136417333943,0.795491229228382,"*",0.706052,"TECPR1","GO:0005765//lysosomal membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005654//nucleoplasm;GO:0031410//cytoplasmic vesicle;GO:0016021//integral component of membrane;GO:0000421//autophagosome membrane","GO:0032266//phosphatidylinositol-3-phosphate binding","GO:0097352//autophagosome maturation;GO:0006914//autophagy","K17988//tectonin beta-propeller repeat-containing protein 1","NP_056210.1//tectonin beta-propeller repeat-containing protein 1 [Homo sapiens]","2//1"]
[55501,2131,9.85,10.14,0.0418620226596019,0.80037993495706,"*",0.711794,"CHST12","GO:0016020//membrane;GO:0030173//integral component of Golgi membrane;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0047756//chondroitin 4-sulfotransferase activity;GO:0050656//3'-phosphoadenosine 5'-phosphosulfate binding;GO:0008146//sulfotransferase activity","GO:0016051//carbohydrate biosynthetic process;GO:0030208//dermatan sulfate biosynthetic process;GO:0030206//chondroitin sulfate biosynthetic process","K04742//chondroitin 4-sulfotransferase 12 [EC:2.8.2.5]","XP_021791295.1//carbohydrate sulfotransferase 12 isoform X1 [Papio anubis];XP_008017044.1//PREDICTED: carbohydrate sulfotransferase 12 isoform X2 [Chlorocebus sabaeus]","4;1//3"]
[51575,3205,10.03,10.32,0.0411213648110735,0.755430117647059,"*",0.65522,"ESF1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005615//extracellular space;GO:0005730//nucleolus","GO:0003723//RNA binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K22023//mucin-6","NP_057733.2//ESF1 homolog [Homo sapiens]","1//3;3//A2MP1"]
[84826,2824,5.98,6.15,0.0404409260284973,0.834130953247828,"*",0.757266,"SFT2D3","GO:0016020//membrane;GO:0016021//integral component of membrane","NA","GO:0015031//protein transport;GO:0016192//vesicle-mediated transport","K22022//mucin-21","XP_002812413.1//PREDICTED: vesicle transport protein SFT2C [Pongo abelii]","3//A2MP1"]
[10809,1988,8.52,8.76,0.0400774393753351,0.833664123853527,"*",0.75679,"STARD10","NA","NA","NA","K20632//deleted in liver cancer protein","XP_008563271.1//PREDICTED: PCTP-like protein [Galeopterus variegatus]","2//1"]
[79073,2412,70.46,72.37,0.0385872967748899,0.49735030186628,"*",0.343668,"TMEM109","GO:0070062//extracellular exosome;GO:0005622//intracellular;GO:0016021//integral component of membrane;GO:0033017//sarcoplasmic reticulum membrane;GO:0005640//nuclear outer membrane","GO:0005244//voltage-gated ion channel activity","GO:0060548//negative regulation of cell death;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0071480//cellular response to gamma radiation","K10599//pre-mRNA-processing factor 19 [EC:2.3.2.27];K17599//transmembrane protein 132","NP_076997.1//transmembrane protein 109 precursor [Homo sapiens]","2//1"]
[113230,1329,2.26,2.32,0.0378020327123845,0.947314593649333,"*",0.902066,"MISP3","NA","NA","NA","K16628//collagen, type VII, alpha;K16519//A-kinase anchor protein 2","NP_001278220.1//uncharacterized protein MISP3 [Homo sapiens]","1//3"]
[55298,2623,13.6,13.96,0.0376922900719507,0.767105193969849,"*",0.668948,"RNF121","GO:0016021//integral component of membrane","NA","NA","K15698//RING finger protein 121","XP_015481775.1//PREDICTED: RING finger protein 121 isoform X4 [Parus major];XP_003254826.1//PREDICTED: RING finger protein 121 isoform X1 [Nomascus leucogenys]","4;1//3"]
[9093,2678,40.45,41.49,0.0366239545543105,0.700079370045703,"*",0.584948,"DNAJA3","GO:0005759//mitochondrial matrix;GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0042645//mitochondrial nucleoid;GO:0031594//neuromuscular junction;GO:0030054//cell junction;GO:0005737//cytoplasm;GO:0019897//extrinsic component of plasma membrane;GO:0005884//actin filament;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0045211//postsynaptic membrane","GO:0005524//ATP binding;GO:0031072//heat shock protein binding;GO:0019901//protein kinase binding;GO:0030695//GTPase regulator activity;GO:0046872//metal ion binding;GO:0051059//NF-kappaB binding;GO:0051082//unfolded protein binding;GO:0030544//Hsp70 protein binding;GO:0005133//interferon-gamma receptor binding;GO:0008134//transcription factor binding","GO:0007528//neuromuscular junction development;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043069//negative regulation of programmed cell death;GO:0042102//positive regulation of T cell proliferation;GO:0033077//T cell differentiation in thymus;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0043065//positive regulation of apoptotic process;GO:0007264//small GTPase mediated signal transduction;GO:0034341//response to interferon-gamma;GO:0006924//activation-induced cell death of T cells;GO:0071340//skeletal muscle acetylcholine-gated channel clustering;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0008285//negative regulation of cell proliferation;GO:0006457//protein folding;GO:0007569//cell aging;GO:0031398//positive regulation of protein ubiquitination;GO:0060336//negative regulation of interferon-gamma-mediated signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0009408//response to heat;GO:0007005//mitochondrion organization;GO:0006264//mitochondrial DNA replication;GO:0006469//negative regulation of protein kinase activity;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0050821//protein stabilization","K09504//DnaJ homolog subfamily A member 3","NP_001128582.1//dnaJ homolog subfamily A member 3, mitochondrial isoform 2 [Homo sapiens];NP_001273445.1//dnaJ homolog subfamily A member 3, mitochondrial isoform 3 [Homo sapiens];NP_005138.3//dnaJ homolog subfamily A member 3, mitochondrial isoform 1 [Homo sapiens]","1//3;2//1;5"]
[9092,3601,18.96,19.44,0.0360692547075217,0.687874720833648,"*",0.570272,"SART1","GO:0005654//nucleoplasm;GO:0016607//nuclear speck;GO:0005737//cytoplasm;GO:0046540//U4/U6 x U5 tri-snRNP complex;GO:0071013//catalytic step 2 spliceosome;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0015030//Cajal body","GO:0003723//RNA binding","GO:0000481//maturation of 5S rRNA;GO:0045585//positive regulation of cytotoxic T cell differentiation;GO:0000398//mRNA splicing, via spliceosome;GO:0045292//mRNA cis splicing, via spliceosome;GO:0097193//intrinsic apoptotic signaling pathway;GO:0007050//cell cycle arrest;GO:0000387//spliceosomal snRNP assembly","K11984//U4/U6.U5 tri-snRNP-associated protein 1","NP_005137.1//U4/U6.U5 tri-snRNP-associated protein 1 [Homo sapiens]",4]
[1666,1374,15.51,15.9,0.0358280791356269,1.01420085361598,"*",0.982392,"DECR1","GO:0005759//mitochondrial matrix;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005739//mitochondrion","GO:0016651//oxidoreductase activity, acting on NAD(P)H;GO:0008670//2,4-dienoyl-CoA reductase (NADPH) activity;GO:0070402//NADPH binding","GO:0006635//fatty acid beta-oxidation;GO:0051289//protein homotetramerization","K13236//2,4-dienoyl-CoA reductase, mitochondrial [EC:1.3.1.34]","NP_001317504.1//2,4-dienoyl-CoA reductase, mitochondrial isoform 2 [Homo sapiens];NP_001350.1//2,4-dienoyl-CoA reductase, mitochondrial isoform 1 precursor [Homo sapiens]","1//3"]
[79716,2181,18.68,19.14,0.0350963747763636,0.764104985040276,"*",0.665088,"NPEPL1","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0004177//aminopeptidase activity;GO:0008235//metalloexopeptidase activity;GO:0030145//manganese ion binding","NA","K09611//probable aminopeptidase NPEPL1 [EC:3.4.11.-]","NP_001191801.1//probable aminopeptidase NPEPL1 isoform 2 [Homo sapiens];NP_078939.3//probable aminopeptidase NPEPL1 isoform 1 [Homo sapiens];NP_001191802.1//probable aminopeptidase NPEPL1 isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[5754,4167,2.07,2.12,0.0344334970638741,0.973089164375529,"*",0.935016,"PTK7","GO:0005887//integral component of plasma membrane;GO:0005925//focal adhesion;GO:0005911//cell-cell junction","GO:1904929//coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway;GO:0005524//ATP binding;GO:0004672//protein kinase activity","GO:0016477//cell migration;GO:0060026//convergent extension;GO:0090103//cochlea morphogenesis;GO:0060484//lung-associated mesenchyme development;GO:0003281//ventricular septum development;GO:0060976//coronary vasculature development;GO:0031532//actin cytoskeleton reorganization;GO:0045198//establishment of epithelial cell apical/basal polarity;GO:0007165//signal transduction;GO:0090179//planar cell polarity pathway involved in neural tube closure;GO:0042060//wound healing;GO:0010976//positive regulation of neuron projection development;GO:0071300//cellular response to retinoic acid;GO:0007155//cell adhesion;GO:0060070//canonical Wnt signaling pathway;GO:0003401//axis elongation;GO:0001736//establishment of planar polarity","K05127//PTK7 protein tyrosine kinase 7 [EC:2.7.10.1]","NP_001257327.1//inactive tyrosine-protein kinase 7 isoform e [Homo sapiens];NP_690619.1//inactive tyrosine-protein kinase 7 isoform b precursor [Homo sapiens];XP_011927673.1//PREDICTED: inactive tyrosine-protein kinase 7 isoform X2 [Cercocebus atys];NP_690621.1//inactive tyrosine-protein kinase 7 isoform d precursor [Homo sapiens];NP_690620.1//inactive tyrosine-protein kinase 7 isoform c precursor [Homo sapiens]","4;1//3;3//A2MP1"]
[7448,1678,5.87,6.01,0.0340044876011333,0.897114159151906,"*",0.837022,"VTN","GO:0043231//intracellular membrane-bounded organelle;GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0072562//blood microparticle;GO:0005578//proteinaceous extracellular matrix;GO:0005796//Golgi lumen;GO:0005576//extracellular region;GO:0048237//rough endoplasmic reticulum lumen;GO:0071062//alphav-beta3 integrin-vitronectin complex;GO:0005604//basement membrane","GO:0005044//scavenger receptor activity;GO:0005178//integrin binding;GO:0005518//collagen binding;GO:0030247//polysaccharide binding;GO:0042802//identical protein binding;GO:0008201//heparin binding;GO:0050840//extracellular matrix binding","GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0030449//regulation of complement activation;GO:0010951//negative regulation of endopeptidase activity;GO:0097421//liver regeneration;GO:0035987//endodermal cell differentiation;GO:0033627//cell adhesion mediated by integrin;GO:0032092//positive regulation of protein binding;GO:0010811//positive regulation of cell-substrate adhesion;GO:0014911//positive regulation of smooth muscle cell migration;GO:0030195//negative regulation of blood coagulation;GO:0048709//oligodendrocyte differentiation;GO:0030949//positive regulation of vascular endothelial growth factor receptor signaling pathway;GO:0051258//protein polymerization;GO:0007160//cell-matrix adhesion;GO:0090303//positive regulation of wound healing;GO:0007155//cell adhesion;GO:0061302//smooth muscle cell-matrix adhesion;GO:0030198//extracellular matrix organization;GO:0006955//immune response;GO:0048260//positive regulation of receptor-mediated endocytosis","K06251//vitronectin","NP_000629.3//vitronectin precursor [Homo sapiens]","3//A2MP1"]
[7319,1869,70.27,71.92,0.0334841222906068,0.724544141543027,"*",0.611422,"UBE2A","NA","NA","NA","K10573//ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]","XP_008017611.1//PREDICTED: ubiquitin-conjugating enzyme E2 A isoform X2 [Chlorocebus sabaeus];XP_003931121.2//PREDICTED: ubiquitin-conjugating enzyme E2 A [Saimiri boliviensis boliviensis];ACQ58139.1//Ubiquitin-conjugating enzyme E2 A [Anoplopoma fimbria]","1//3;3//A2MP1;2//1"]
[57016,1610,1750.18,1791.12,0.0333586911535569,0.00261140688797364,"*",0.000793852,"AKR1B10","NA","NA","NA","K00011//aldehyde reductase [EC:1.1.1.21]","XP_007981173.1//PREDICTED: aldo-keto reductase family 1 member B10-like isoform X2 [Chlorocebus sabaeus]",4]
[81691,2796,2.2,2.25,0.0324214776923774,0.965724519490695,"*",0.925884,"REXO5","GO:0070062//extracellular exosome;GO:0005730//nucleolus","GO:0003723//RNA binding;GO:0004527//exonuclease activity","NA","K14570//RNA exonuclease 1 [EC:3.1.-.-]","NP_112203.2//RNA exonuclease 5 isoform 1 [Homo sapiens];NP_001138396.1//RNA exonuclease 5 isoform 2 [Homo sapiens]","1//3;2//1"]
[84433,4432,0.89,0.91,0.0320612092322986,0.955834349164756,"*",0.91341,"CARD11","GO:0042101//T cell receptor complex;GO:0070062//extracellular exosome;GO:0045121//membrane raft;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0001772//immunological synapse;GO:0005737//cytoplasm","GO:0050700//CARD domain binding;GO:0004385//guanylate kinase activity","GO:0042102//positive regulation of T cell proliferation;GO:0045580//regulation of T cell differentiation;GO:0031295//T cell costimulation;GO:0001819//positive regulation of cytokine production;GO:0030890//positive regulation of B cell proliferation;GO:0030183//B cell differentiation;GO:0050776//regulation of immune response;GO:0048872//homeostasis of number of cells;GO:0045061//thymic T cell selection;GO:0007165//signal transduction;GO:0045577//regulation of B cell differentiation;GO:0050852//T cell receptor signaling pathway;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0002377//immunoglobulin production;GO:0070970//interleukin-2 secretion;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0045086//positive regulation of interleukin-2 biosynthetic process;GO:0042100//B cell proliferation;GO:0042981//regulation of apoptotic process","K07367//caspase recruitment domain-containing protein 11","NP_115791.3//caspase recruitment domain-containing protein 11 [Homo sapiens]","1//3;5"]
[8428,4634,22.37,22.87,0.0318911093525536,0.659829987602357,"*",0.539752,"STK24","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005794//Golgi apparatus","GO:0046872//metal ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0008349//MAP kinase kinase kinase kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0045296//cadherin binding","GO:0007165//signal transduction;GO:0007346//regulation of mitotic cell cycle;GO:0009267//cellular response to starvation;GO:0008631//intrinsic apoptotic signaling pathway in response to oxidative stress;GO:0006468//protein phosphorylation;GO:0030336//negative regulation of cell migration;GO:0042542//response to hydrogen peroxide;GO:0046777//protein autophosphorylation;GO:0097194//execution phase of apoptosis;GO:0048812//neuron projection morphogenesis;GO:0048679//regulation of axon regeneration;GO:0031098//stress-activated protein kinase signaling cascade;GO:0042981//regulation of apoptotic process","K08838//serine/threonine-protein kinase 24/25/MST4 [EC:2.7.11.1]","NP_003567.2//serine/threonine-protein kinase 24 isoform a precursor [Homo sapiens];XP_020145852.1//serine/threonine-protein kinase 24 isoform X1 [Microcebus murinus]","4;1//3;3//A2MP1"]
[64838,1697,2.28,2.33,0.0312961304895385,0.954840431801796,"*",0.911982,"FNDC4","GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","NA","GO:0071559//response to transforming growth factor beta;GO:0050728//negative regulation of inflammatory response","K19719//collagen, type II, alpha;K16628//collagen, type VII, alpha;K05120//tyrosine kinase receptor 1 [EC:2.7.10.1]","XP_017380232.1//PREDICTED: LOW QUALITY PROTEIN: fibronectin type III domain-containing protein 4, partial [Cebus capucinus imitator]","2//1"]
[84667,1699,1.39,1.42,0.0308060467811744,0.939764134890781,"*",0.891464,"HES7","GO:0005634//nucleus","GO:0003677//DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0008134//transcription factor binding;GO:0046983//protein dimerization activity","GO:0007498//mesoderm development;GO:0006351//transcription, DNA-templated;GO:0048511//rhythmic process;GO:0036342//post-anal tail morphogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0014807//regulation of somitogenesis;GO:0001756//somitogenesis;GO:0007219//Notch signaling pathway;GO:0001501//skeletal system development","K09087//hairy and enhancer of split 2/6/7","XP_016880721.1//PREDICTED: transcription factor HES-7 isoform X1 [Homo sapiens];NP_115969.2//transcription factor HES-7 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[55829,1267,31.29,31.96,0.0305657496870551,0.81293585006993,"*",0.727744,"SELENOS","GO:0005783//endoplasmic reticulum;GO:0005881//cytoplasmic microtubule;GO:0034362//low-density lipoprotein particle;GO:0036502//Derlin-1-VIMP complex;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0034361//very-low-density lipoprotein particle;GO:0036513//Derlin-1 retrotranslocation complex;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane","GO:0016209//antioxidant activity;GO:0004872//receptor activity;GO:0051117//ATPase binding;GO:1990381//ubiquitin-specific protease binding;GO:0019899//enzyme binding","GO:0030970//retrograde protein transport, ER to cytosol;GO:0006111//regulation of gluconeogenesis;GO:0016567//protein ubiquitination;GO:0032715//negative regulation of interleukin-6 production;GO:0071222//cellular response to lipopolysaccharide;GO:0032720//negative regulation of tumor necrosis factor production;GO:0051771//negative regulation of nitric-oxide synthase biosynthetic process;GO:2000110//negative regulation of macrophage apoptotic process;GO:0050728//negative regulation of inflammatory response;GO:0045454//cell redox homeostasis;GO:0002865//negative regulation of acute inflammatory response to antigenic stimulus;GO:0009749//response to glucose;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0045184//establishment of protein localization;GO:0046325//negative regulation of glucose import;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0006886//intracellular protein transport;GO:0051775//response to redox state;GO:0032869//cellular response to insulin stimulus;GO:0045719//negative regulation of glycogen biosynthetic process;GO:0034599//cellular response to oxidative stress;GO:0080164//regulation of nitric oxide metabolic process;GO:0006983//ER overload response;GO:1902236//negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway","K14025//selenoprotein S","NP_060915.2//selenoprotein S isoform 1 [Homo sapiens]","2//1;5"]
[10131,2275,104.87,107.03,0.0294132064902876,0.746351442015347,"*",0.64543,"TRAP1","GO:0005759//mitochondrial matrix;GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005654//nucleoplasm;GO:0005811//lipid droplet;GO:0005758//mitochondrial intermembrane space;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0005164//tumor necrosis factor receptor binding;GO:0003723//RNA binding;GO:0005524//ATP binding;GO:0051082//unfolded protein binding;GO:0019901//protein kinase binding","GO:0006457//protein folding;GO:1901856//negative regulation of cellular respiration;GO:1903427//negative regulation of reactive oxygen species biosynthetic process;GO:1903751//negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide;GO:0006950//response to stress;GO:0009386//translational attenuation;GO:0061077//chaperone-mediated protein folding","K09488//TNF receptor-associated protein 1","NP_001258978.1//heat shock protein 75 kDa, mitochondrial isoform 2 [Homo sapiens];XP_004057143.1//PREDICTED: heat shock protein 75 kDa, mitochondrial [Gorilla gorilla gorilla]","1//3;2//1"]
[55190,2413,1.49,1.52,0.028758992981424,0.889562883351293,"*",0.826858,"NUDT11","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005737//cytoplasm","GO:0052841//inositol bisdiphosphate tetrakisphosphate diphosphatase activity;GO:0050072//m7G(5')pppN diphosphatase activity;GO:0052844//inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity;GO:0034431//bis(5'-adenosyl)-hexaphosphatase activity;GO:0016787//hydrolase activity;GO:0008486//diphosphoinositol-polyphosphate diphosphatase activity;GO:0052842//inositol diphosphate pentakisphosphate diphosphatase activity;GO:0052843//inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity;GO:0052845//inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity;GO:0052848//inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity;GO:0052846//inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity;GO:0046872//metal ion binding;GO:0000298//endopolyphosphatase activity;GO:0034432//bis(5'-adenosyl)-pentaphosphatase activity;GO:0052847//inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity;GO:0052840//inositol diphosphate tetrakisphosphate diphosphatase activity","GO:0071543//diphosphoinositol polyphosphate metabolic process;GO:0043647//inositol phosphate metabolic process;GO:1901907//diadenosine pentaphosphate catabolic process;GO:1901911//adenosine 5'-(hexahydrogen pentaphosphate) catabolic process;GO:1901909//diadenosine hexaphosphate catabolic process","K07766//diphosphoinositol-polyphosphate diphosphatase [EC:3.6.1.52]","NP_060629.2//diphosphoinositol polyphosphate phosphohydrolase 3-beta [Homo sapiens]","3//A2MP1"]
[339983,5894,8.01,8.17,0.0285338357369734,0.794536006209865,"*",0.704856,"NAT8L","GO:0005759//mitochondrial matrix;GO:0030867//rough endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0031966//mitochondrial membrane;GO:0005737//cytoplasm","GO:0017188//aspartate N-acetyltransferase activity","GO:0008652//cellular amino acid biosynthetic process","K18309//aspartate N-acetyltransferase [EC:2.3.1.17]","NP_848652.2//N-acetylaspartate synthetase [Homo sapiens]","3//A2MP1"]
[4836,4916,44.35,45.21,0.027707813130554,0.58286493764988,"*",0.426038,"NMT1","GO:0019898//extrinsic component of membrane;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0019107//myristoyltransferase activity;GO:0004379//glycylpeptide N-tetradecanoyltransferase activity","GO:1900740//positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway;GO:0018008//N-terminal peptidyl-glycine N-myristoylation;GO:0006499//N-terminal protein myristoylation;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0001701//in utero embryonic development;GO:0042180//cellular ketone metabolic process","K00671//glycylpeptide N-tetradecanoyltransferase [EC:2.3.1.97]","XP_008010555.1//PREDICTED: glycylpeptide N-tetradecanoyltransferase 1 [Chlorocebus sabaeus]",4]
[22928,2351,38.31,39.05,0.0276015226054614,0.72484572026105,"*",0.611858,"SEPHS2","GO:0005829//cytosol","GO:0005524//ATP binding;GO:0004756//selenide, water dikinase activity","GO:0016260//selenocysteine biosynthetic process;GO:0001887//selenium compound metabolic process;GO:0016259//selenocysteine metabolic process","K01008//selenide, water dikinase [EC:2.7.9.3]","NP_036380.2//selenide, water dikinase 2 [Homo sapiens]","3//A2MP1"]
[84932,2889,15.31,15.6,0.0270717462498229,0.875740109748662,"*",0.80924,"RAB2B","GO:0070062//extracellular exosome;GO:0098793//presynapse;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0000139//Golgi membrane","GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0045921//positive regulation of exocytosis;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport","K07878//Ras-related protein Rab-2B","XP_014998743.1//PREDICTED: ras-related protein Rab-2B isoform X2 [Macaca mulatta];NP_116235.2//ras-related protein Rab-2B isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[100507607,1491,8.59,8.75,0.0266248855812277,0.90996768727467,"*",0.85323,"NPIPB9","GO:0005654//nucleoplasm","NA","NA","K01896//medium-chain acyl-CoA synthetase [EC:6.2.1.2]","NP_001274180.1//nuclear pore complex-interacting protein family member B9 isoform 2 [Homo sapiens];NP_001274179.1//nuclear pore complex-interacting protein family member B9 isoform 1 [Homo sapiens]","1//3"]
[1445,2754,46.35,47.2,0.0262175207363105,0.678339119332828,"*",0.560116,"CSK","GO:0070062//extracellular exosome;GO:0045121//membrane raft;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0005829//cytosol;GO:0005911//cell-cell junction;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0042802//identical protein binding;GO:0019903//protein phosphatase binding;GO:0005102//receptor binding;GO:0046872//metal ion binding;GO:0004713//protein tyrosine kinase activity;GO:0008022//protein C-terminus binding;GO:0034236//protein kinase A catalytic subunit binding;GO:0070064//proline-rich region binding","GO:0038083//peptidyl-tyrosine autophosphorylation;GO:0042127//regulation of cell proliferation;GO:0032715//negative regulation of interleukin-6 production;GO:0031295//T cell costimulation;GO:0007420//brain development;GO:0045779//negative regulation of bone resorption;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0050765//negative regulation of phagocytosis;GO:0045087//innate immune response;GO:0008285//negative regulation of cell proliferation;GO:0010989//negative regulation of low-density lipoprotein particle clearance;GO:0030154//cell differentiation;GO:0050852//T cell receptor signaling pathway;GO:0043406//positive regulation of MAP kinase activity;GO:0006468//protein phosphorylation;GO:0042997//negative regulation of Golgi to plasma membrane protein transport;GO:0048709//oligodendrocyte differentiation;GO:0007417//central nervous system development;GO:0033673//negative regulation of kinase activity;GO:0046777//protein autophosphorylation;GO:0002250//adaptive immune response;GO:0071375//cellular response to peptide hormone stimulus;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0001817//regulation of cytokine production;GO:0034332//adherens junction organization;GO:0060368//regulation of Fc receptor mediated stimulatory signaling pathway","K05728//c-src tyrosine kinase [EC:2.7.10.2]","EDL25918.1//c-src tyrosine kinase, isoform CRA_a, partial [Mus musculus]","1//3;2//1"]
[10671,1126,33.16,33.74,0.0250159667918157,0.845082363811357,"*",0.769536,"DCTN6","GO:0005869//dynactin complex;GO:0005829//cytosol;GO:0005813//centrosome;GO:0000777//condensed chromosome kinetochore","NA","GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0006888//ER to Golgi vesicle-mediated transport","K10428//dynactin 6","NP_006562.1//dynactin subunit 6 [Homo sapiens]","3//A2MP1"]
[54499,4490,21.31,21.68,0.0248341635711681,0.751088499747092,"*",0.650702,"TMCO1","GO:0005783//endoplasmic reticulum;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0000139//Golgi membrane","GO:0005262//calcium channel activity","GO:0070588//calcium ion transmembrane transport;GO:0032469//endoplasmic reticulum calcium ion homeostasis;GO:0006983//ER overload response","K21891//calcium load-activated calcium channel","NP_061899.2//calcium load-activated calcium channel isoform a [Homo sapiens];NP_001243093.1//calcium load-activated calcium channel isoform b [Homo sapiens];NP_001243094.1//calcium load-activated calcium channel isoform c [Homo sapiens]","4;1//3"]
[51593,3029,61.34,62.37,0.0240240923125063,0.637369392191728,"*",0.516112,"SRRT","NA","NA","NA","K19607//X-linked retinitis pigmentosa GTPase regulator","XP_005250464.1//PREDICTED: serrate RNA effector molecule homolog isoform X3 [Homo sapiens];XP_005250463.1//PREDICTED: serrate RNA effector molecule homolog isoform X2 [Homo sapiens];XP_005250462.1//PREDICTED: serrate RNA effector molecule homolog isoform X1 [Homo sapiens];XP_005250465.1//PREDICTED: serrate RNA effector molecule homolog isoform X4 [Homo sapiens]","1//3;5"]
[102723553,870,14.43,14.66,0.0228138036426139,0.942347081625931,"*",0.895448,"SMIM11B","NA","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K06245//laminin, beta 4;K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K01064//wingless-type MMTV integration site family, member 9","BAG64432.1//unnamed protein product [Homo sapiens]","1//3"]
[131870,3310,3.81,3.87,0.0225425686510882,3.23378248106366E-3,"*",1.004914E-3,"NUDT16","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm","GO:0030515//snoRNA binding;GO:0000287//magnesium ion binding;GO:0035870//dITP diphosphatase activity;GO:0003729//mRNA binding;GO:0050072//m7G(5')pppN diphosphatase activity;GO:0042802//identical protein binding;GO:1990003//IDP phosphatase activity;GO:0042803//protein homodimerization activity;GO:0098519//nucleotide phosphatase activity, acting on free nucleotides;GO:1901641//ITP binding;GO:0008235//metalloexopeptidase activity;GO:0050897//cobalt ion binding;GO:0016787//hydrolase activity;GO:0097383//dIDP diphosphatase activity;GO:0005525//GTP binding;GO:1901640//XTP binding;GO:0030145//manganese ion binding","GO:0006402//mRNA catabolic process;GO:0035863//dITP catabolic process;GO:2000233//negative regulation of rRNA processing;GO:0016077//snoRNA catabolic process;GO:0006382//adenosine to inosine editing;GO:0046709//IDP catabolic process;GO:0034656//nucleobase-containing small molecule catabolic process;GO:2000781//positive regulation of double-strand break repair;GO:0090068//positive regulation of cell cycle process;GO:1901639//XDP catabolic process;GO:0008284//positive regulation of cell proliferation","K16855//U8 snoRNA-decapping enzyme [EC:3.6.1.62 3.6.1.64]","NP_001165377.1//U8 snoRNA-decapping enzyme isoform 1 [Homo sapiens];NP_001165376.1//U8 snoRNA-decapping enzyme isoform 3 [Homo sapiens];NP_689608.2//U8 snoRNA-decapping enzyme isoform 2 [Homo sapiens]","1//3;2//1"]
[83596,1867,44,44.67,0.0218027308912343,0.758919260305564,"*",0.659244,"BCL2L12","GO:0016020//membrane;GO:0005634//nucleus","GO:0002039//p53 binding","GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:1902166//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:1990001//inhibition of cysteine-type endopeptidase activity involved in apoptotic process;GO:0042981//regulation of apoptotic process;GO:2000773//negative regulation of cellular senescence;GO:0006915//apoptotic process","K19720//collagen, type III, alpha","NP_001035758.1//bcl-2-like protein 12 isoform 3 [Homo sapiens];NP_001269448.1//bcl-2-like protein 12 isoform 5 [Homo sapiens];NP_001269449.1//bcl-2-like protein 12 isoform 6 [Homo sapiens];NP_001269446.1//bcl-2-like protein 12 isoform 2 [Homo sapiens];NP_001269450.1//bcl-2-like protein 12 isoform 7 [Homo sapiens];NP_001269445.1//bcl-2-like protein 12 isoform 4 [Homo sapiens];NP_619580.1//bcl-2-like protein 12 isoform 1 [Homo sapiens]","1//3"]
[4968,1832,20.84,21.15,0.0213023857288039,0.650643082314964,"*",0.529956,"OGG1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0043234//protein complex;GO:0016607//nuclear speck;GO:0016363//nuclear matrix;GO:0005739//mitochondrion","GO:0008017//microtubule binding;GO:0016829//lyase activity;GO:0003684//damaged DNA binding;GO:0034039//8-oxo-7,8-dihydroguanine DNA N-glycosylase activity;GO:0140078//class I DNA-(apurinic or apyrimidinic site) lyase activity;GO:0019104//DNA N-glycosylase activity;GO:0032357//oxidized purine DNA binding;GO:0140080//class III/IV DNA-(apurinic or apyrimidinic site) lyase activity;GO:0004519//endonuclease activity;GO:0008534//oxidized purine nucleobase lesion DNA N-glycosylase activity","GO:0006284//base-excision repair;GO:0006355//regulation of transcription, DNA-templated;GO:0009416//response to light stimulus;GO:1901291//negative regulation of double-strand break repair via single-strand annealing;GO:0006289//nucleotide-excision repair;GO:0045471//response to ethanol;GO:0033158//regulation of protein import into nucleus, translocation;GO:0045007//depurination;GO:0032355//response to estradiol;GO:0045008//depyrimidination;GO:0051593//response to folic acid;GO:0033683//nucleotide-excision repair, DNA incision;GO:0071276//cellular response to cadmium ion;GO:0006974//cellular response to DNA damage stimulus;GO:0042493//response to drug;GO:0043066//negative regulation of apoptotic process;GO:0002526//acute inflammatory response;GO:0007568//aging;GO:0006979//response to oxidative stress;GO:0009314//response to radiation","K03660//N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]","NP_058438.1//N-glycosylase/DNA lyase isoform 2e [Homo sapiens];NP_058213.1//N-glycosylase/DNA lyase isoform 1c [Homo sapiens];NP_001341578.1//N-glycosylase/DNA lyase isoform 1e [Homo sapiens];NP_002533.1//N-glycosylase/DNA lyase isoform 1a [Homo sapiens];NP_001341577.1//N-glycosylase/DNA lyase isoform 1d [Homo sapiens];NP_058436.1//N-glycosylase/DNA lyase isoform 2c [Homo sapiens];NP_058437.1//N-glycosylase/DNA lyase isoform 2d [Homo sapiens];NP_058214.1//N-glycosylase/DNA lyase isoform 2a [Homo sapiens];NP_001341580.1//N-glycosylase/DNA lyase isoform 2g [Homo sapiens];NP_058434.1//N-glycosylase/DNA lyase isoform 2b [Homo sapiens];NP_001341581.1//N-glycosylase/DNA lyase isoform 2h [Homo sapiens];XP_009198515.1//N-glycosylase/DNA lyase isoform X1 [Papio anubis];NP_001341579.1//N-glycosylase/DNA lyase isoform 2f [Homo sapiens]","1//3;3//A2MP1;2//1;5"]
[439921,2315,49.22,49.93,0.0206622488719328,0.818878736081184,"*",0.737524,"MXRA7","NA","NA","NA","K16628//collagen, type VII, alpha;K01064//wingless-type MMTV integration site family, member 9","XP_011897738.1//PREDICTED: matrix-remodeling-associated protein 7 isoform X4 [Cercocebus atys];XP_011897735.1//PREDICTED: matrix-remodeling-associated protein 7 isoform X2 [Cercocebus atys];XP_011897737.1//PREDICTED: matrix-remodeling-associated protein 7 isoform X3 [Cercocebus atys]","3//A2MP1;2//1"]
[158067,2197,0.72,0.73,0.0198995574377048,0.923237545617649,"*",0.869776,"AK8","GO:0036126//sperm flagellum;GO:0005829//cytosol;GO:0005930//axoneme","GO:0005524//ATP binding;GO:0019206//nucleoside kinase activity;GO:0004550//nucleoside diphosphate kinase activity;GO:0004127//cytidylate kinase activity;GO:0004017//adenylate kinase activity","GO:0006165//nucleoside diphosphate phosphorylation;GO:0021591//ventricular system development;GO:0015949//nucleobase-containing small molecule interconversion;GO:0009142//nucleoside triphosphate biosynthetic process","K00939//adenylate kinase [EC:2.7.4.3]","NP_689785.1//adenylate kinase 8 isoform 1 [Homo sapiens];NP_001304888.1//adenylate kinase 8 isoform 3 [Homo sapiens]","1//3;2//1"]
[11282,2528,108.45,109.93,0.0195550998374388,0.697301390912505,"*",0.58123,"MGAT4B","GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0008375//acetylglucosaminyltransferase activity;GO:0046872//metal ion binding;GO:0016758//transferase activity, transferring hexosyl groups;GO:0008454//alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity","GO:0006487//protein N-linked glycosylation;GO:0005975//carbohydrate metabolic process;GO:0006491//N-glycan processing","K00738//alpha-1,3-mannosylglycoprotein beta-1,4-N-acetylglucosaminyltransferase A/B [EC:2.4.1.145]","EAW53789.1//mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B, isoform CRA_b [Homo sapiens];NP_463459.1//alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B isoform 2 [Homo sapiens]","4;3//A2MP1"]
[4289,11201,5.32,5.39,0.0188590272513158,0.858979409710857,"*",0.788536,"MKLN1","GO:0001726//ruffle;GO:0005938//cell cortex;GO:0005829//cytosol","GO:0042802//identical protein binding","GO:0007160//cell-matrix adhesion;GO:0031532//actin cytoskeleton reorganization;GO:0007165//signal transduction;GO:0008360//regulation of cell shape","K17985//activating molecule in BECN1-regulated autophagy protein 1;K15696//RING finger protein 113B","XP_003791660.2//PREDICTED: muskelin [Otolemur garnettii];XP_004608311.1//PREDICTED: muskelin [Sorex araneus]","4;1//3"]
[64925,1851,10.6,10.73,0.0175858113059605,0.927922887134231,"*",0.875468,"CCDC71","NA","NA","NA","K06243//laminin, beta 2;K11275//histone H1/5","NP_075054.3//coiled-coil domain-containing protein 71 [Homo sapiens]","3//A2MP1"]
[377,3556,100.09,101.3,0.0173363325434042,0.625768583820891,"*",0.502174,"ARF3","NA","NA","NA","K07938//ADP-ribosylation factor 3","ELK08405.1//Protein Wnt-10b [Pteropus alecto]","2//1"]
[79180,2424,106.28,107.51,0.0166007248218602,0.698516790449733,"*",0.582418,"EFHD2","GO:0045121//membrane raft","GO:0005509//calcium ion binding;GO:0045296//cadherin binding","NA","K17336//plastin-3;K19475//WAS/WASL-interacting protein;K01311//chymotrypsin C [EC:3.4.21.2]","NP_077305.2//EF-hand domain-containing protein D2 [Homo sapiens]",5]
[11273,3987,118.75,120.04,0.0155877106052535,0.60859171261939,"*",0.450748,"ATXN2L","GO:0016020//membrane;GO:0010494//cytoplasmic stress granule;GO:0005829//cytosol;GO:0016607//nuclear speck","GO:0003723//RNA binding;GO:0045296//cadherin binding","GO:0034063//stress granule assembly;GO:0010603//regulation of cytoplasmic mRNA processing body assembly","K11653//AT-rich interactive domain-containing protein 1;K21125//mucin-5AC;K09188//histone-lysine N-methyltransferase MLL3 [EC:2.1.1.43]","XP_012360621.1//PREDICTED: ataxin-2-like protein [Nomascus leucogenys];NP_009176.2//ataxin-2-like protein isoform A [Homo sapiens];NP_059867.3//ataxin-2-like protein isoform F [Homo sapiens];NP_001295159.1//ataxin-2-like protein isoform G [Homo sapiens];NP_663760.1//ataxin-2-like protein isoform B [Homo sapiens];NP_680780.1//ataxin-2-like protein isoform C [Homo sapiens]","1//3;3//A2MP1;2//1"]
[128272,3357,1.92,1.94,0.0149503414659716,0.967401787234042,"*",0.927916,"ARHGEF19","GO:0005829//cytosol","GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity","GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0043065//positive regulation of apoptotic process;GO:0042060//wound healing;GO:0043547//positive regulation of GTPase activity;GO:0035023//regulation of Rho protein signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0032956//regulation of actin cytoskeleton organization","K20691//Rho guanine nucleotide exchange factor 19","XP_009447334.2//PREDICTED: rho guanine nucleotide exchange factor 19 isoform X1 [Pan troglodytes]",4]
[7323,4124,53.49,54.03,0.014491478281281,0.860082673120185,"*",0.789818,"UBE2D3","GO:0070062//extracellular exosome;GO:0010008//endosome membrane;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0005524//ATP binding;GO:0061631//ubiquitin conjugating enzyme activity;GO:0004842//ubiquitin-protein transferase activity","GO:0070936//protein K48-linked ubiquitination;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:1903955//positive regulation of protein targeting to mitochondrion;GO:0016567//protein ubiquitination;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0051865//protein autoubiquitination;GO:0000209//protein polyubiquitination;GO:0006281//DNA repair;GO:0006513//protein monoubiquitination;GO:0030509//BMP signaling pathway;GO:0070979//protein K11-linked ubiquitination;GO:0006915//apoptotic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0006464//cellular protein modification process","K06689//ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]","NP_871622.1//ubiquitin-conjugating enzyme E2 D3 isoform 3 [Homo sapiens];XP_021251741.1//ubiquitin-conjugating enzyme E2 D3 isoform X1 [Numida meleagris];XP_021565848.1//ubiquitin-conjugating enzyme E2 D3 isoform X4 [Carlito syrichta]","6;1//3;3//A2MP1;2//1"]
[221002,3243,1.07,1.08,0.0134205157623218,1.02205801224621,"*",0.99269,"RASGEF1A","GO:0005829//cytosol;GO:0005622//intracellular","GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005085//guanyl-nucleotide exchange factor activity","GO:0000165//MAPK cascade;GO:0016477//cell migration;GO:0046579//positive regulation of Ras protein signal transduction;GO:0007264//small GTPase mediated signal transduction","K08020//Rap guanine nucleotide exchange factor 6;K03781//catalase [EC:1.11.1.6];K08018//Rap guanine nucleotide exchange factor 2;K03099//son of sevenless","NP_001269791.1//ras-GEF domain-containing family member 1A isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[1140,2437,4.3,4.34,0.013358382855019,0.975407697553358,"*",0.938404,"CHRNB1","GO:0005887//integral component of plasma membrane;GO:0005892//acetylcholine-gated channel complex;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0045202//synapse;GO:0045211//postsynaptic membrane","GO:0015276//ligand-gated ion channel activity;GO:0042166//acetylcholine binding;GO:0015267//channel activity;GO:0022848//acetylcholine-gated cation-selective channel activity","GO:0035095//behavioral response to nicotine;GO:0007165//signal transduction;GO:0006936//muscle contraction;GO:0098655//cation transmembrane transport;GO:0048747//muscle fiber development;GO:0006812//cation transport;GO:0007274//neuromuscular synaptic transmission;GO:0007271//synaptic transmission, cholinergic;GO:0001941//postsynaptic membrane organization;GO:0003009//skeletal muscle contraction;GO:0050877//nervous system process;GO:0042391//regulation of membrane potential","K04812//nicotinic acetylcholine receptor beta-1","NP_000738.2//acetylcholine receptor subunit beta precursor [Homo sapiens]","2//1"]
[26524,5558,3.41,3.44,0.0126368256779255,0.953895753688766,"*",0.910602,"LATS2","GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005815//microtubule organizing center;GO:0005829//cytosol","GO:0046872//metal ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding","GO:0046620//regulation of organ growth;GO:0035329//hippo signaling;GO:0006468//protein phosphorylation;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0035556//intracellular signal transduction;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0018105//peptidyl-serine phosphorylation;GO:0051301//cell division;GO:0000082//G1/S transition of mitotic cell cycle;GO:0009755//hormone-mediated signaling pathway","K08791//serine/threonine-protein kinase LATS1/2 [EC:2.7.11.1]","NP_055387.2//serine/threonine-protein kinase LATS2 [Homo sapiens]","2//1"]
[728642,3212,7,7.06,0.0123132614388513,0.95667254812099,"*",0.91475,"CDK11A","NA","NA","NA","K08818//cell division cycle 2-like [EC:2.7.11.22]","XP_016807764.1//PREDICTED: cyclin-dependent kinase 11B isoform X8 [Pan troglodytes];XP_016807743.1//PREDICTED: cyclin-dependent kinase 11B isoform X5 [Pan troglodytes];EDL15018.1//cell division cycle 2-like 1, isoform CRA_b, partial [Mus musculus];AAC72077.1//PITSLRE protein kinase alpha SV1 isoform [Homo sapiens]","1//3;3//A2MP1"]
[7088,4150,25.69,25.91,0.0123021252792775,0.862772183823529,"*",0.793314,"TLE1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol","GO:0001106//RNA polymerase II transcription corepressor activity;GO:0042802//identical protein binding;GO:0008134//transcription factor binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0007165//signal transduction;GO:0006355//regulation of transcription, DNA-templated;GO:0030178//negative regulation of Wnt signaling pathway;GO:0006351//transcription, DNA-templated;GO:0010628//positive regulation of gene expression;GO:1904837//beta-catenin-TCF complex assembly;GO:2000811//negative regulation of anoikis;GO:0009887//animal organ morphogenesis;GO:0007275//multicellular organism development;GO:0016055//Wnt signaling pathway;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling","K04497//groucho","XP_020822580.1//transducin-like enhancer protein 1 isoform X4 [Phascolarctos cinereus];XP_020822577.1//transducin-like enhancer protein 1 isoform X1 [Phascolarctos cinereus];XP_020822582.1//transducin-like enhancer protein 1 isoform X6 [Phascolarctos cinereus]","4;1//3"]
[11266,1283,22.66,22.84,0.0114147895423272,0.939113822768093,"*",0.890318,"DUSP12","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0008270//zinc ion binding;GO:0019900//kinase binding;GO:0004725//protein tyrosine phosphatase activity;GO:0016791//phosphatase activity;GO:0003676//nucleic acid binding","GO:0006464//cellular protein modification process;GO:0016311//dephosphorylation;GO:0033133//positive regulation of glucokinase activity","K14819//dual specificity phosphatase 12 [EC:3.1.3.16 3.1.3.48]","XP_514446.3//PREDICTED: dual specificity protein phosphatase 12 [Pan troglodytes]","2//1"]
[10001,2386,15.26,15.37,0.0103622028562407,0.924705559835303,"*",0.87168,"MED6","GO:0016020//membrane;GO:0070847//core mediator complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000151//ubiquitin ligase complex;GO:0016592//mediator complex","GO:0061630//ubiquitin protein ligase activity;GO:0003677//DNA binding;GO:0003713//transcription coactivator activity;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0001128//RNA polymerase II transcription coactivator activity involved in preinitiation complex assembly;GO:0008134//transcription factor binding","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0019827//stem cell population maintenance;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0051123//RNA polymerase II transcriptional preinitiation complex assembly","K15128//mediator of RNA polymerase II transcription subunit 6","XP_005321246.1//mediator of RNA polymerase II transcription subunit 6 isoform X2 [Ictidomys tridecemlineatus];NP_005457.2//mediator of RNA polymerase II transcription subunit 6 isoform 2 [Homo sapiens];NP_001271140.1//mediator of RNA polymerase II transcription subunit 6 isoform 4 [Homo sapiens];NP_001271138.1//mediator of RNA polymerase II transcription subunit 6 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[5877,3227,10.11,10.18,0.00995456417268062,0.962711145321485,"*",0.922332,"RABIF","NA","NA","NA","K19952//guanine nucleotide exchange factor","XP_017752084.1//PREDICTED: guanine nucleotide exchange factor MSS4 [Rhinopithecus bieti]",4]
[100144595,2362,1.63,1.64,0.00882385038700641,1.02205792263056,"*",0.99237,"LOC100144595","NA","NA","NA","K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K01064//wingless-type MMTV integration site family, member 9;K12025//tripartite motif-containing protein 52","EAX11463.1//hCG2038403, partial [Homo sapiens]","1//3"]
[10424,3790,20.14,20.26,0.00857049079435359,0.91332654518795,"*",0.857866,"PGRMC2","GO:0012505//endomembrane system;GO:0016020//membrane;GO:0005635//nuclear envelope;GO:0016021//integral component of membrane","GO:0003707//steroid hormone receptor activity;GO:0020037//heme binding;GO:0005496//steroid binding","NA","K17278//membrane-associated progesterone receptor component","XP_005631865.2//membrane-associated progesterone receptor component 2, partial [Canis lupus familiaris]",4]
[441518,2038,6.83,6.87,0.00842452052800982,0.978960645823854,"*",0.942864,"RTL8B","NA","NA","NA","K19720//collagen, type III, alpha","EAX11737.1//hCG14613, isoform CRA_a, partial [Homo sapiens]","1//3"]
[56731,2296,108.71,109.21,0.00662030824394461,0.860267955555556,"*",0.790042,"SLC2A4RG","GO:0005634//nucleus;GO:0016607//nuclear speck;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0001158//enhancer sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K22020//mucin-19","NP_064446.2//SLC2A4 regulator [Homo sapiens]","3//A2MP1"]
[84513,1329,22.59,22.68,0.00573636954914447,0.375624997788945,"*",0.233972,"PLPP5","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0008195//phosphatidate phosphatase activity","GO:0007165//signal transduction;GO:0046839//phospholipid dephosphorylation;GO:0006644//phospholipid metabolic process","K18693//diacylglycerol diphosphate phosphatase / phosphatidate phosphatase [EC:3.1.3.81 3.1.3.4]","XP_011542974.1//PREDICTED: phospholipid phosphatase 5 isoform X5 [Homo sapiens];XP_519712.3//PREDICTED: phospholipid phosphatase 5 isoform X1 [Pan troglodytes];NP_001096030.1//phospholipid phosphatase 5 isoform 3 [Homo sapiens];NP_001341386.1//phospholipid phosphatase 5 isoform 7 [Homo sapiens];NP_001341381.1//phospholipid phosphatase 5 isoform 4 [Homo sapiens];XP_001170536.2//PREDICTED: phospholipid phosphatase 5 isoform X2 [Pan troglodytes];XP_010383591.1//PREDICTED: phosphatidate phosphatase PPAPDC1B isoform X4 [Rhinopithecus roxellana];NP_001341383.1//phospholipid phosphatase 5 isoform 5 [Homo sapiens]","1//3;3//A2MP1"]
[25861,3870,2.72,2.73,0.00529429966951302,0.975391193804503,"*",0.938266,"WHRN","GO:0001917//photoreceptor inner segment;GO:0032391//photoreceptor connecting cilium;GO:0032426//stereocilium tip;GO:0005737//cytoplasm;GO:0005884//actin filament;GO:0036064//ciliary basal body;GO:1990075//periciliary membrane compartment;GO:0030426//growth cone;GO:0002142//stereocilia ankle link complex;GO:0032420//stereocilium;GO:1990696//USH2 complex","GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity","GO:0045184//establishment of protein localization;GO:0060088//auditory receptor cell stereocilium organization;GO:0001895//retina homeostasis;GO:1990227//paranodal junction maintenance;GO:0010628//positive regulation of gene expression;GO:0021694//cerebellar Purkinje cell layer formation;GO:0060122//inner ear receptor cell stereocilium organization;GO:0050953//sensory perception of light stimulus;GO:0007605//sensory perception of sound","K21879//whirlin","NP_001166896.1//whirlin isoform 3 [Homo sapiens];XP_011516786.1//PREDICTED: whirlin isoform X1 [Homo sapiens];NP_056219.3//whirlin isoform 1 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[5250,1691,215.15,215.86,0.00475308881719779,0.902274320835565,"*",0.843644,"SLC25A3","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0043209//myelin sheath;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0015114//phosphate ion transmembrane transporter activity;GO:0015293//symporter activity;GO:0032403//protein complex binding","GO:0006810//transport;GO:0006839//mitochondrial transport","K15102//solute carrier family 25 (mitochondrial phosphate transporter), member 3","NP_005879.1//phosphate carrier protein, mitochondrial isoform a precursor [Homo sapiens];NP_002626.1//phosphate carrier protein, mitochondrial isoform b precursor [Homo sapiens]","3//A2MP1;2//1"]
[28985,9797,7.05,7.07,0.00408695752324295,0.953950520393443,"*",0.910714,"MCTS1","GO:0005829//cytosol;GO:0022627//cytosolic small ribosomal subunit;GO:0005737//cytoplasm;GO:0005886//plasma membrane","GO:0003723//RNA binding;GO:0003743//translation initiation factor activity","GO:0075522//IRES-dependent viral translational initiation;GO:0002188//translation reinitiation;GO:0006355//regulation of transcription, DNA-templated;GO:0040008//regulation of growth;GO:0006351//transcription, DNA-templated;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0032790//ribosome disassembly;GO:0001731//formation of translation preinitiation complex","K07575//PUA domain protein","XP_019573218.1//PREDICTED: LOW QUALITY PROTEIN: malignant T-cell-amplified sequence 1-like [Rhinolophus sinicus];XP_019488830.1//PREDICTED: malignant T-cell-amplified sequence 1 [Hipposideros armiger]","1//3;2//1"]
[8480,1815,32.55,32.63,0.00354144403886669,0.968061711228551,"*",0.928852,"RAE1","NA","NA","NA","K14298//mRNA export factor","XP_017392061.1//PREDICTED: mRNA export factor [Cebus capucinus imitator];XP_005260640.1//PREDICTED: mRNA export factor isoform X3 [Homo sapiens]","1//3;3//A2MP1"]
[332,2626,80.03,80.19,2.88142907595624E-3,0.889530945922284,"*",0.826884,"BIRC5","GO:0005874//microtubule;GO:0005881//cytoplasmic microtubule;GO:0005737//cytoplasm;GO:0032133//chromosome passenger complex;GO:0030496//midbody;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005819//spindle;GO:0000777//condensed chromosome kinetochore;GO:0005876//spindle microtubule;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0000775//chromosome, centromeric region;GO:0005814//centriole;GO:0000228//nuclear chromosome;GO:0031021//interphase microtubule organizing center","GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process;GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity;GO:0051087//chaperone binding;GO:0042803//protein homodimerization activity;GO:0008017//microtubule binding;GO:0004842//ubiquitin-protein transferase activity;GO:0050897//cobalt ion binding;GO:0015631//tubulin binding;GO:0046872//metal ion binding;GO:0008536//Ran GTPase binding;GO:0008270//zinc ion binding;GO:0048037//cofactor binding;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0019899//enzyme binding","GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0016925//protein sumoylation;GO:0000278//mitotic cell cycle;GO:0007059//chromosome segregation;GO:0007346//regulation of mitotic cell cycle;GO:0016567//protein ubiquitination;GO:0051303//establishment of chromosome localization;GO:1990001//inhibition of cysteine-type endopeptidase activity involved in apoptotic process;GO:0031536//positive regulation of exit from mitosis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0031577//spindle checkpoint;GO:0000910//cytokinesis;GO:0045931//positive regulation of mitotic cell cycle;GO:0006468//protein phosphorylation;GO:0006351//transcription, DNA-templated;GO:0043066//negative regulation of apoptotic process;GO:0006915//apoptotic process;GO:0090307//mitotic spindle assembly;GO:0007062//sister chromatid cohesion;GO:0007605//sensory perception of sound;GO:0051301//cell division;GO:0009966//regulation of signal transduction;GO:0000086//G2/M transition of mitotic cell cycle;GO:0042981//regulation of apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0031503//protein complex localization","K08731//baculoviral IAP repeat-containing protein 5","AAA19687.1//effector cell protease receptor 1, partial [Homo sapiens];XP_008011275.1//PREDICTED: baculoviral IAP repeat-containing protein 5 isoform X2 [Chlorocebus sabaeus]","1//3;2//1"]
[64968,1017,24.06,24.09,0.00179775106239416,1.01350608846353,"*",0.981148,"MRPS6","NA","NA","NA","K02990//small subunit ribosomal protein S6;K14383//solute carrier family 5 (sodium/myo-inositol cotransporter), member 3","XP_531445.5//PREDICTED: 28S ribosomal protein S6, mitochondrial [Pan troglodytes]","3//A2MP1"]
[64342,2403,26.82,26.84,0.00107543429570972,0.983803946531698,"*",0.94913,"HS1BP3","GO:0005783//endoplasmic reticulum;GO:0005739//mitochondrion","GO:0035091//phosphatidylinositol binding","GO:0042981//regulation of apoptotic process","K03006//DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]","NP_071905.3//HCLS1-binding protein 3 [Homo sapiens]","3//A2MP1"]
[5223,1863,290.94,291.06,5.94925798487971E-4,0.938920558938123,"*",0.890076,"PGAM1","GO:0034774//secretory granule lumen;GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0043209//myelin sheath;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005576//extracellular region;GO:1904813//ficolin-1-rich granule lumen","GO:0004619//phosphoglycerate mutase activity;GO:0016787//hydrolase activity;GO:0004082//bisphosphoglycerate mutase activity;GO:0046538//2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity;GO:0019901//protein kinase binding","GO:0061621//canonical glycolysis;GO:0006094//gluconeogenesis;GO:0043312//neutrophil degranulation;GO:0006096//glycolytic process;GO:0043456//regulation of pentose-phosphate shunt;GO:0006110//regulation of glycolytic process;GO:0045730//respiratory burst","K01834//2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]","NP_001304008.1//phosphoglycerate mutase 1 isoform 2 [Homo sapiens];XP_017358259.1//PREDICTED: phosphoglycerate mutase 1 [Cebus capucinus imitator]","1//3;3//A2MP1"]
[286499,3292,0.1,0.1,0,1.01748933622781,"*",0.997616,"FAM133A","NA","NA","NA","K10779//transcriptional regulator ATRX [EC:3.6.4.12]","XP_007990408.1//PREDICTED: protein FAM133A [Chlorocebus sabaeus]","1//3;2//1"]
[11251,2910,0.38,0.38,0,1.02111780048787,"*",0.995804,"PTGDR2","GO:0005887//integral component of plasma membrane;GO:0005622//intracellular;GO:0005886//plasma membrane;GO:0043005//neuron projection","GO:0001785//prostaglandin J receptor activity;GO:0004958//prostaglandin F receptor activity;GO:0042923//neuropeptide binding;GO:0004956//prostaglandin D receptor activity;GO:0004930//G-protein coupled receptor activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0019722//calcium-mediated signaling;GO:0045745//positive regulation of G-protein coupled receptor protein signaling pathway;GO:2000255//negative regulation of male germ cell proliferation;GO:0007268//chemical synaptic transmission;GO:0006955//immune response;GO:0006935//chemotaxis;GO:0007218//neuropeptide signaling pathway;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger","K06715//G protein-coupled receptor 44","NP_004769.2//prostaglandin D2 receptor 2 [Homo sapiens]","2//1"]
[6660,5926,0.01,0.01,0,0.655284600739827,"*",0.499032,"SOX5","GO:0005634//nucleus","GO:0003677//DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0071560//cellular response to transforming growth factor beta stimulus;GO:2000741//positive regulation of mesenchymal stem cell differentiation;GO:0061036//positive regulation of cartilage development;GO:0006366//transcription from RNA polymerase II promoter;GO:0032332//positive regulation of chondrocyte differentiation;GO:0055059//asymmetric neuroblast division","K09269//transcription factor SOX5/6/13 (SOX group D)","XP_006727807.1//PREDICTED: transcription factor SOX-5 isoform X1 [Leptonychotes weddellii];XP_021584484.1//transcription factor SOX-5 isoform X1 [Ictidomys tridecemlineatus];NP_001248343.1//transcription factor SOX-5 isoform d [Homo sapiens];XP_007966099.1//PREDICTED: transcription factor SOX-5 isoform X2 [Chlorocebus sabaeus];NP_821078.1//transcription factor SOX-5 isoform c [Homo sapiens];XP_016875378.1//PREDICTED: transcription factor SOX-5 isoform X2 [Homo sapiens]","4;1//3;3//A2MP1;2//1;5"]
[57121,2716,0.03,0.03,0,1.01005608865248,"*",0.998548,"LPAR5","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004930//G-protein coupled receptor activity","NA","K08390//lysophosphatidic acid receptor 5","NP_065133.1//lysophosphatidic acid receptor 5 [Homo sapiens]","1//3;5"]
[83729,2480,0.87,0.87,0,1.02168244811837,"*",0.994244,"INHBE","GO:0005615//extracellular space;GO:0005576//extracellular region","GO:0008083//growth factor activity;GO:0005125//cytokine activity;GO:0005160//transforming growth factor beta receptor binding;GO:0005179//hormone activity","GO:0060395//SMAD protein signal transduction;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0043408//regulation of MAPK cascade;GO:0042981//regulation of apoptotic process;GO:0048468//cell development","K04667//inhibin, beta","NP_113667.1//inhibin beta E chain preproprotein [Homo sapiens]",4]
[146862,5354,0.01,0.01,0,1.0096085671245,"*",0.998548,"UNC45B","GO:0005829//cytosol","GO:0051879//Hsp90 protein binding","GO:0030154//cell differentiation;GO:0007517//muscle organ development;GO:0002088//lens development in camera-type eye;GO:0061077//chaperone-mediated protein folding","K21991//protein unc-45","XP_537726.2//protein unc-45 homolog B [Canis lupus familiaris];NP_775259.1//protein unc-45 homolog B isoform 1 [Homo sapiens];NP_001295210.1//protein unc-45 homolog B isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[6507,3834,0.02,0.02,0,1.00941689355778,"*",0.998548,"SLC1A3","GO:0016020//membrane;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0043025//neuronal cell body;GO:0043005//neuron projection","GO:0005313//L-glutamate transmembrane transporter activity;GO:0016595//glutamate binding;GO:0046872//metal ion binding;GO:0015293//symporter activity;GO:0005314//high-affinity glutamate transmembrane transporter activity;GO:0015501//glutamate:sodium symporter activity;GO:0015171//amino acid transmembrane transporter activity","GO:0070779//D-aspartate import;GO:0009416//response to light stimulus;GO:0006537//glutamate biosynthetic process;GO:0046677//response to antibiotic;GO:0140009//L-aspartate import across plasma membrane;GO:0001504//neurotransmitter uptake;GO:1902476//chloride transmembrane transport;GO:0009611//response to wounding;GO:0042493//response to drug;GO:0089711//L-glutamate transmembrane transport;GO:0050806//positive regulation of synaptic transmission;GO:0009449//gamma-aminobutyric acid biosynthetic process;GO:0140016//D-aspartate import across plasma membrane;GO:0098712//L-glutamate import across plasma membrane;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0006811//ion transport;GO:0051938//L-glutamate import;GO:0031223//auditory behavior;GO:0007605//sensory perception of sound;GO:0021545//cranial nerve development;GO:0007268//chemical synaptic transmission;GO:0071805//potassium ion transmembrane transport;GO:0050885//neuromuscular process controlling balance;GO:0014047//glutamate secretion","K05614//solute carrier family 1 (glial high affinity glutamate transporter), member 3","NP_001276869.1//excitatory amino acid transporter 1 isoform 5 [Homo sapiens];NP_001160168.1//excitatory amino acid transporter 1 isoform 3 [Homo sapiens];NP_001160167.1//excitatory amino acid transporter 1 isoform 2 [Homo sapiens];NP_001276868.1//excitatory amino acid transporter 1 isoform 4 [Homo sapiens];NP_004163.3//excitatory amino acid transporter 1 isoform 1 [Homo sapiens]","1//3;4;2//1"]
[284467,1144,0.08,0.08,0,1.00922529275546,"*",0.998548,"FAM19A3","GO:0005615//extracellular space","NA","GO:1903979//negative regulation of microglial cell activation;GO:1903980//positive regulation of microglial cell activation","NA","XP_004026418.2//PREDICTED: protein FAM19A3 [Gorilla gorilla gorilla];NP_001004440.1//protein FAM19A3 isoform 2 precursor [Homo sapiens]","1//3;2//1"]
[10966,1776,5.08,5.08,0,1.01921565115228,"*",0.988398,"RAB40B","GO:0005635//nuclear envelope;GO:0005622//intracellular;GO:0048471//perinuclear region of cytoplasm","GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0016567//protein ubiquitination;GO:1990967//multi-organism toxin transport;GO:0035556//intracellular signal transduction","K07928//Ras-related protein Rab-40","BAD92948.1//RAB40B, member RAS oncogene family variant, partial [Homo sapiens]","2//1"]
[22917,1972,0.08,0.08,0,1.01334548560534,"*",0.998184,"ZP1","GO:0031012//extracellular matrix;GO:0030141//secretory granule;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005578//proteinaceous extracellular matrix","NA","GO:0007339//binding of sperm to zona pellucida","K19926//zona pellucida sperm-binding protein 1","NP_997224.2//zona pellucida sperm-binding protein 1 precursor [Homo sapiens]","3//A2MP1"]
[3263,1635,0.1,0.1,0,1.01328108896797,"*",0.998184,"HPX","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0072562//blood microparticle;GO:0005623//cell;GO:0005576//extracellular region;GO:0071682//endocytic vesicle lumen","GO:0015232//heme transporter activity;GO:0046872//metal ion binding","GO:0020027//hemoglobin metabolic process;GO:0006879//cellular iron ion homeostasis;GO:0060335//positive regulation of interferon-gamma-mediated signaling pathway;GO:0015886//heme transport;GO:0016032//viral process;GO:0002639//positive regulation of immunoglobulin production;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0006898//receptor-mediated endocytosis;GO:0042168//heme metabolic process;GO:0002925//positive regulation of humoral immune response mediated by circulating immunoglobulin","K18977//hemopexin","NP_000604.1//hemopexin precursor [Homo sapiens]","2//1"]
[1768,12795,0.01,0.01,0,0.652655736695595,"*",0.499032,"DNAH6","GO:0005929//cilium;GO:0005874//microtubule;GO:0030286//dynein complex;GO:0005737//cytoplasm;GO:0005858//axonemal dynein complex","GO:0051959//dynein light intermediate chain binding;GO:0045505//dynein intermediate chain binding;GO:0005524//ATP binding;GO:0045503//dynein light chain binding;GO:0008569//ATP-dependent microtubule motor activity, minus-end-directed","GO:0001539//cilium or flagellum-dependent cell motility;GO:0007018//microtubule-based movement;GO:0060271//cilium assembly","K10408//dynein heavy chain, axonemal","NP_001361.1//dynein heavy chain 6, axonemal [Homo sapiens]","1//3"]
[64753,3241,0.37,0.37,0,0.915152865787018,"*",0.859696,"CCDC136","NA","NA","NA","K20282//GRIP and coiled-coil domain-containing protein 2;K04437//filamin","XP_010377047.1//PREDICTED: coiled-coil domain-containing protein 136 isoform X1 [Rhinopithecus roxellana];XP_013974613.1//coiled-coil domain-containing protein 136 isoform X5 [Canis lupus familiaris]","1//3;4"]
[3662,5329,0.01,0.01,0,0.652281905572375,"*",0.499032,"IRF4","GO:0016020//membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0000788//nuclear nucleosome","GO:0016279//protein-lysine N-methyltransferase activity;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0008134//transcription factor binding;GO:0003700//DNA binding transcription factor activity","GO:0072540//T-helper 17 cell lineage commitment;GO:0060337//type I interferon signaling pathway;GO:0034122//negative regulation of toll-like receptor signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0043967//histone H4 acetylation;GO:0045622//regulation of T-helper cell differentiation;GO:0043388//positive regulation of DNA binding;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0042110//T cell activation;GO:0042832//defense response to protozoan;GO:0045404//positive regulation of interleukin-4 biosynthetic process;GO:0045082//positive regulation of interleukin-10 biosynthetic process;GO:0045368//positive regulation of interleukin-13 biosynthetic process;GO:0045086//positive regulation of interleukin-2 biosynthetic process;GO:0043966//histone H3 acetylation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0043011//myeloid dendritic cell differentiation","K09445//interferon regulatory factor 4","NP_001182215.1//interferon regulatory factor 4 isoform 2 [Homo sapiens];NP_002451.2//interferon regulatory factor 4 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[343,1315,0.06,0.06,0,1.0083958624352,"*",0.998548,"AQP8","GO:0005887//integral component of plasma membrane;GO:0045177//apical part of cell;GO:0005886//plasma membrane","GO:0015250//water channel activity","GO:0006833//water transport;GO:0006810//transport;GO:0034220//ion transmembrane transport;GO:0071320//cellular response to cAMP","K09869//aquaporin-8","NP_001160.2//aquaporin-8 [Homo sapiens]","2//1"]
[162333,3476,0.05,0.05,0,1.01289488095541,"*",0.998184,"2019-03-10","NA","GO:0008270//zinc ion binding","NA","K10665//E3 ubiquitin-protein ligase MARCH10 [EC:2.3.2.27]","XP_016788190.1//PREDICTED: probable E3 ubiquitin-protein ligase MARCH10 isoform X6 [Pan troglodytes];XP_003811371.1//PREDICTED: probable E3 ubiquitin-protein ligase MARCH10 isoform X1 [Pan paniscus];XP_001145535.2//PREDICTED: probable E3 ubiquitin-protein ligase MARCH10 isoform X1 [Pan troglodytes]","1//3;3//A2MP1;2//1"]
[9077,1984,0.04,0.04,0,1.00814092731639,"*",0.998548,"DIRAS3","GO:0016020//membrane;GO:0005622//intracellular;GO:0005886//plasma membrane","GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0007165//signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0006349//regulation of gene expression by genetic imprinting;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity","K07842//DIRAS family, GTP-binding Ras-like 3","NP_004666.1//GTP-binding protein Di-Ras3 precursor [Homo sapiens]","3//A2MP1"]
[401027,2259,0.11,0.11,0,1.01587961685042,"*",0.997882,"C2orf66","GO:0005576//extracellular region","NA","NA","NA","NP_998773.1//uncharacterized protein C2orf66 precursor [Homo sapiens]","2//1"]
[26018,4812,0.58,0.58,0,1.02193482413549,"*",0.993466,"LRIG1","GO:0016021//integral component of membrane","NA","GO:0060384//innervation;GO:0007605//sensory perception of sound;GO:0032474//otolith morphogenesis;GO:0022405//hair cycle process","K19511//peroxidase [EC:1.11.1.7]","XP_007983103.1//PREDICTED: leucine-rich repeats and immunoglobulin-like domains protein 1 isoform X1 [Chlorocebus sabaeus]","2//1"]
[8294,370,0.49,0.49,0,1.01263757246285,"*",0.998184,"HIST1H4I","GO:0005634//nucleus;GO:0000786//nucleosome","GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity","GO:0006334//nucleosome assembly;GO:0006352//DNA-templated transcription, initiation","K11253//histone H3;K11254//histone H4","XP_014590042.1//PREDICTED: histone H4 [Equus caballus]","2//1"]
[4284,2608,0.03,0.03,0,1.00756779432759,"*",0.998548,"MIP","GO:0005921//gap junction;GO:0005783//endoplasmic reticulum;GO:0005887//integral component of plasma membrane;GO:0016324//apical plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0015250//water channel activity;GO:0005212//structural constituent of eye lens;GO:0005516//calmodulin binding","GO:0006833//water transport;GO:1990349//gap junction-mediated intercellular transport;GO:0051289//protein homotetramerization;GO:0034220//ion transmembrane transport;GO:0050896//response to stimulus;GO:0045785//positive regulation of cell adhesion;GO:0007601//visual perception;GO:0002088//lens development in camera-type eye","K09863//aquaporin-0","NP_036196.1//lens fiber major intrinsic protein [Homo sapiens]","3//A2MP1"]
[55083,13593,0.01,0.01,0,1.00731327767603,"*",0.998548,"KIF26B","GO:0005874//microtubule;GO:0005737//cytoplasm;GO:0005871//kinesin complex","GO:0005524//ATP binding;GO:0003777//microtubule motor activity;GO:0008017//microtubule binding","GO:0030010//establishment of cell polarity;GO:0022409//positive regulation of cell-cell adhesion;GO:0072092//ureteric bud invasion","K10404//kinesin family member 26","NP_060482.2//kinesin-like protein KIF26B [Homo sapiens]",4]
[10396,8225,0.01,0.01,0,1.00693174370305,"*",0.998548,"ATP8A1","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0005783//endoplasmic reticulum;GO:0005802//trans-Golgi network;GO:0000139//Golgi membrane;GO:0035577//azurophil granule membrane;GO:0005794//Golgi apparatus;GO:0035579//specific granule membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0042584//chromaffin granule membrane","GO:0000287//magnesium ion binding;GO:0005524//ATP binding;GO:0019829//cation-transporting ATPase activity;GO:0004012//phospholipid-translocating ATPase activity","GO:0061092//positive regulation of phospholipid translocation;GO:0030335//positive regulation of cell migration;GO:0045332//phospholipid translocation;GO:0048194//Golgi vesicle budding;GO:0034220//ion transmembrane transport;GO:0043312//neutrophil degranulation;GO:0007612//learning","K14802//phospholipid-transporting ATPase [EC:3.6.3.1]","XP_016863134.1//PREDICTED: phospholipid-transporting ATPase IA isoform X5 [Homo sapiens];XP_005248100.1//PREDICTED: phospholipid-transporting ATPase IA isoform X3 [Homo sapiens]","1//3;2//1"]
[8787,2531,0.15,0.15,0,1.01562071156419,"*",0.997882,"RGS9","GO:0097381//photoreceptor disc membrane;GO:0005634//nucleus;GO:0001917//photoreceptor inner segment;GO:0005834//heterotrimeric G-protein complex;GO:0001750//photoreceptor outer segment;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0004871//signal transducer activity;GO:0032403//protein complex binding;GO:0005096//GTPase activator activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0006457//protein folding;GO:0007399//nervous system development;GO:0009968//negative regulation of signal transduction;GO:0007601//visual perception;GO:0035556//intracellular signal transduction;GO:0043627//response to estrogen;GO:0007212//dopamine receptor signaling pathway;GO:0008277//regulation of G-protein coupled receptor protein signaling pathway","K13765//regulator of G-protein signaling 9","NP_001075424.1//regulator of G-protein signaling 9 isoform 2 [Homo sapiens];NP_003826.2//regulator of G-protein signaling 9 isoform 1 [Homo sapiens];NP_001159405.1//regulator of G-protein signaling 9 isoform 3 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[79831,2481,1.26,1.26,0,1.02209722878681,"*",0.993112,"KDM8","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol","GO:0046872//metal ion binding;GO:0051864//histone demethylase activity (H3-K36 specific);GO:0003682//chromatin binding;GO:0032452//histone demethylase activity","GO:0006351//transcription, DNA-templated;GO:0070544//histone H3-K36 demethylation;GO:0000086//G2/M transition of mitotic cell cycle;GO:0045893//positive regulation of transcription, DNA-templated","K10277//lysine-specific demethylase 8 [EC:1.14.11.27]","NP_001138820.1//lysine-specific demethylase 8 isoform 1 [Homo sapiens]","1//3;2//1"]
[5455,4525,0.02,0.02,0,1.00642348110291,"*",0.998548,"POU3F3","GO:0005634//nucleus","GO:0071837//HMG box domain binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0021799//cerebral cortex radially oriented cell migration;GO:0072218//metanephric ascending thin limb development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0072236//metanephric loop of Henle development;GO:0072227//metanephric macula densa development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0021869//forebrain ventricular zone progenitor cell division;GO:0007588//excretion;GO:0006351//transcription, DNA-templated;GO:0043066//negative regulation of apoptotic process;GO:0007417//central nervous system development;GO:0010628//positive regulation of gene expression;GO:0072240//metanephric DCT cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0072233//metanephric thick ascending limb development;GO:0048878//chemical homeostasis;GO:0008284//positive regulation of cell proliferation","K09365//POU domain transcription factor, class 3","NP_006227.1//POU domain, class 3, transcription factor 3 [Homo sapiens]","2//1"]
[240,2420,0.1,0.1,0,1.01542661918716,"*",0.997882,"ALOX5","GO:0034774//secretory granule lumen;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0005615//extracellular space;GO:0005635//nuclear envelope;GO:0016363//nuclear matrix;GO:0005829//cytosol;GO:0005576//extracellular region;GO:1904813//ficolin-1-rich granule lumen;GO:0005641//nuclear envelope lumen","GO:0004051//arachidonate 5-lipoxygenase activity;GO:0005506//iron ion binding","GO:0002540//leukotriene production involved in inflammatory response;GO:0006691//leukotriene metabolic process;GO:2001300//lipoxin metabolic process;GO:0019372//lipoxygenase pathway;GO:0043312//neutrophil degranulation;GO:0019370//leukotriene biosynthetic process","K00461//arachidonate 5-lipoxygenase [EC:1.13.11.34]","NP_001243082.1//arachidonate 5-lipoxygenase isoform 2 [Homo sapiens];NP_000689.1//arachidonate 5-lipoxygenase isoform 1 [Homo sapiens];NP_001243083.1//arachidonate 5-lipoxygenase isoform 3 [Homo sapiens];NP_001307790.1//arachidonate 5-lipoxygenase isoform 4 [Homo sapiens]","4;1//3;2//1"]
[338645,5185,0.13,0.13,0,1.01961911065574,"*",0.996768,"LUZP2","NA","NA","NA","K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K02927//large subunit ribosomal protein L40e;K15696//RING finger protein 113B;K17985//activating molecule in BECN1-regulated autophagy protein 1;K12025//tripartite motif-containing protein 52","CAD90000.1//hypothetical protein, partial [Homo sapiens];XP_009458391.2//PREDICTED: leucine zipper protein 2 isoform X1 [Pan troglodytes];XP_011849319.1//PREDICTED: leucine zipper protein 2 isoform X2 [Mandrillus leucophaeus]","1//3;3//A2MP1"]
[140831,2831,0.56,0.56,0,1.02116809688403,"*",0.995022,"ZSWIM3","NA","GO:0008270//zinc ion binding","NA","K17604//zinc finger SWIM domain-containing protein 3","NP_542790.2//zinc finger SWIM domain-containing protein 3 [Homo sapiens]","3//A2MP1"]
[84303,1020,9.59,9.59,0,1.0189163883796,"*",0.988044,"CHCHD6","GO:0005829//cytosol;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0061617//MICOS complex","NA","GO:0042407//cristae formation;GO:0006974//cellular response to DNA damage stimulus","K17564//coiled-coil-helix-coiled-coil-helix domain-containing protein 6, mitochondrial","NP_115719.1//MICOS complex subunit MIC25 isoform 2 [Homo sapiens];NP_001307539.1//MICOS complex subunit MIC25 isoform 1 [Homo sapiens]","1//3;2//1"]
[1045,3513,0.18,0.18,0,1.01948854091433,"*",0.996768,"CDX2","GO:0017053//transcriptional repressor complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0043234//protein complex;GO:0000794//condensed nuclear chromosome","GO:0003714//transcription corepressor activity;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0001227//transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding","GO:0009952//anterior/posterior pattern specification;GO:0001829//trophectodermal cell differentiation;GO:0035019//somatic stem cell population maintenance;GO:0001568//blood vessel development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0060711//labyrinthine layer development;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0008333//endosome to lysosome transport;GO:0045597//positive regulation of cell differentiation;GO:0030154//cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0060575//intestinal epithelial cell differentiation;GO:0009887//animal organ morphogenesis;GO:0014807//regulation of somitogenesis;GO:0009948//anterior/posterior axis specification;GO:0045197//establishment or maintenance of epithelial cell apical/basal polarity;GO:0008284//positive regulation of cell proliferation","K22234//homeobox protein CDX2","NP_001256.3//homeobox protein CDX-2 isoform 1 [Homo sapiens];NP_001341629.1//homeobox protein CDX-2 isoform 2 [Homo sapiens]","1//3;5"]
[2049,4234,0.13,0.13,0,0.862596,"*",0.793368,"EPHB3","NA","NA","NA","K05112//Eph receptor B3 [EC:2.7.10.1]","XP_013369041.1//PREDICTED: ephrin type-B receptor 3 [Chinchilla lanigera]","3//A2MP1"]
[2705,1623,0.05,0.05,0,1.00566204854675,"*",0.998548,"GJB1","GO:0005922//connexin complex;GO:0016021//integral component of membrane;GO:0016328//lateral plasma membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005737//cytoplasm","GO:0005243//gap junction channel activity;GO:0042803//protein homodimerization activity","GO:0006810//transport;GO:0007399//nervous system development;GO:0007154//cell communication;GO:0007267//cell-cell signaling;GO:1905867//epididymis development;GO:0016264//gap junction assembly;GO:0015868//purine ribonucleotide transport;GO:0051259//protein oligomerization","K07620//gap junction beta-1 protein","OBS83720.1//hypothetical protein A6R68_22323 [Neotoma lepida];NP_000157.1//gap junction beta-1 protein [Homo sapiens]","2//1;5"]
[5324,6874,0.01,0.01,0,0.632705790006325,"*",0.500968,"PLAG1","GO:0005634//nucleus;GO:0016607//nuclear speck","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0060252//positive regulation of glial cell proliferation;GO:0006351//transcription, DNA-templated;GO:0010629//negative regulation of gene expression;GO:0010628//positive regulation of gene expression;GO:0035264//multicellular organism growth;GO:0006915//apoptotic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0060736//prostate gland growth;GO:0022612//gland morphogenesis","K19484//zinc finger protein PLAG1","BAD92368.1//Pleiomorphic adenoma gene 1 variant, partial [Homo sapiens];NP_002646.2//zinc finger protein PLAG1 isoform a [Homo sapiens]","1//3;2//1"]
[26531,2229,0.18,0.18,0,0.830727588125389,"*",0.751524,"OR11A1","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity","NA","K04257//olfactory receptor","NP_039225.1//olfactory receptor 11A1 [Homo sapiens]","3//A2MP1"]
[8547,1046,0.08,0.08,0,1.005218411394,"*",0.998548,"FCN3","NA","NA","NA","K10104//ficolin","XP_017390181.1//PREDICTED: ficolin-3 [Cebus capucinus imitator];XP_012606027.1//ficolin-3 isoform X2 [Microcebus murinus]","3//A2MP1;2//1"]
[763,1084,0.08,0.08,0,1.00515506660785,"*",0.998548,"CA5A","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0008270//zinc ion binding;GO:0004089//carbonate dehydratase activity","GO:0015701//bicarbonate transport;GO:0006730//one-carbon metabolic process","K01672//carbonic anhydrase [EC:4.2.1.1]","NP_001730.1//carbonic anhydrase 5A, mitochondrial precursor [Homo sapiens]","1//3"]
[1606,2648,3.82,3.82,0,0.954993518940883,"*",0.912188,"DGKA","GO:0016020//membrane;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0004143//diacylglycerol kinase activity;GO:0003951//NAD+ kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0005509//calcium ion binding;GO:0005543//phospholipid binding","GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0046486//glycerolipid metabolic process;GO:0030168//platelet activation;GO:0035556//intracellular signal transduction;GO:0046834//lipid phosphorylation;GO:0046339//diacylglycerol metabolic process;GO:0006654//phosphatidic acid biosynthetic process","K00901//diacylglycerol kinase (ATP) [EC:2.7.1.107]","XP_016778734.1//PREDICTED: diacylglycerol kinase alpha isoform X1 [Pan troglodytes];NP_001337964.1//diacylglycerol kinase alpha isoform b [Homo sapiens];XP_018893847.1//PREDICTED: diacylglycerol kinase alpha isoform X3 [Gorilla gorilla gorilla]","4;1//3;2//1"]
[4892,5424,0.01,0.01,0,1.00464859557851,"*",0.998548,"NRAP","NA","GO:0003779//actin binding;GO:0046872//metal ion binding","NA","K18267//nebulin","XP_008049334.1//nebulin-related-anchoring protein isoform X2 [Carlito syrichta];XP_006183562.1//PREDICTED: nebulin-related-anchoring protein isoform X1 [Camelus ferus];XP_014413711.1//PREDICTED: nebulin-related-anchoring protein isoform X2 [Camelus ferus];XP_010968128.1//PREDICTED: LOW QUALITY PROTEIN: nebulin-related-anchoring protein [Camelus bactrianus]","4;1//3;3//A2MP1"]
[221303,1050,0.23,0.23,0,1.01478018003565,"*",0.997882,"FAM162B","NA","NA","NA","K04622//G protein-coupled receptor family C group 6 member A","XP_003827624.1//PREDICTED: protein FAM162B isoform X2 [Pan paniscus]","2//1"]
[8747,2666,0.03,0.03,0,1.00420585192647,"*",0.998548,"ADAM21","GO:0030424//axon;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0043025//neuronal cell body","GO:0046872//metal ion binding;GO:0008237//metallopeptidase activity;GO:0004222//metalloendopeptidase activity","GO:0007338//single fertilization;GO:0007339//binding of sperm to zona pellucida","K08610//disintegrin and metalloproteinase domain-containing protein 21 [EC:3.4.24.-]","NP_003804.2//disintegrin and metalloproteinase domain-containing protein 21 preproprotein [Homo sapiens]","3//A2MP1"]
[1087,2379,0.03,0.03,0,1.00388984530178,"*",0.998548,"CEACAM7","GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0031225//anchored component of membrane","NA","GO:0006501//C-terminal protein lipidation","K06499//carcinoembryonic antigen-related cell adhesion molecule","NP_001278414.1//carcinoembryonic antigen-related cell adhesion molecule 7 preproprotein [Homo sapiens]","4;1//3"]
[6622,3214,0.13,0.13,0,1.01737651162197,"*",0.997378,"SNCA","GO:0016020//membrane;GO:0030424//axon;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0005938//cell cortex;GO:0030054//cell junction;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0045202//synapse","GO:0048487//beta-tubulin binding;GO:0042802//identical protein binding;GO:0005507//copper ion binding;GO:0005509//calcium ion binding;GO:0043014//alpha-tubulin binding;GO:1903136//cuprous ion binding;GO:0050544//arachidonic acid binding","GO:0048148//behavioral response to cocaine;GO:0034599//cellular response to oxidative stress;GO:0008344//adult locomotory behavior;GO:0014059//regulation of dopamine secretion;GO:0071280//cellular response to copper ion;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007568//aging","K04528//alpha-synuclein","NP_000336.1//alpha-synuclein isoform NACP140 [Homo sapiens];NP_009292.1//alpha-synuclein isoform NACP112 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[23768,8117,0.2,0.2,0,1.02130945928925,"*",0.994904,"FLRT2","GO:0070062//extracellular exosome;GO:0005925//focal adhesion;GO:0031090//organelle membrane;GO:0005737//cytoplasm;GO:0005578//proteinaceous extracellular matrix;GO:0043005//neuron projection;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0005789//endoplasmic reticulum membrane;GO:0045202//synapse;GO:0005886//plasma membrane","GO:0005057//signal transducer activity, downstream of receptor;GO:0004860//protein kinase inhibitor activity;GO:0030674//protein binding, bridging;GO:0045499//chemorepellent activity;GO:0005104//fibroblast growth factor receptor binding","GO:0071711//basement membrane organization;GO:0061343//cell adhesion involved in heart morphogenesis;GO:0046426//negative regulation of JAK-STAT cascade;GO:0051965//positive regulation of synapse assembly;GO:0003007//heart morphogenesis;GO:0006469//negative regulation of protein kinase activity;GO:2001222//regulation of neuron migration;GO:0019221//cytokine-mediated signaling pathway;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0007411//axon guidance","K16362//leucine-rich repeat transmembrane protein FLRT","NP_037363.1//leucine-rich repeat transmembrane protein FLRT2 precursor [Homo sapiens]","1//3;5"]
[4838,1876,0.09,0.09,0,1.01148130017762,"*",0.998184,"NODAL","GO:0005615//extracellular space","GO:0070698//type I activin receptor binding;GO:0008083//growth factor activity;GO:0005125//cytokine activity;GO:0005160//transforming growth factor beta receptor binding;GO:0016015//morphogen activity","GO:0002085//inhibition of neuroepithelial cell differentiation;GO:0001890//placenta development;GO:0060460//left lung morphogenesis;GO:1901383//negative regulation of chorionic trophoblast cell proliferation;GO:0007420//brain development;GO:0001842//neural fold formation;GO:0001892//embryonic placenta development;GO:2000036//regulation of stem cell population maintenance;GO:1901164//negative regulation of trophoblast cell migration;GO:0060766//negative regulation of androgen receptor signaling pathway;GO:0060802//epiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification;GO:0045766//positive regulation of angiogenesis;GO:0048468//cell development;GO:0042074//cell migration involved in gastrulation;GO:0001893//maternal placenta development;GO:1900164//nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry;GO:0010470//regulation of gastrulation;GO:0030509//BMP signaling pathway;GO:0019827//stem cell population maintenance;GO:0033505//floor plate morphogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0048327//axial mesodermal cell fate specification;GO:0060137//maternal process involved in parturition;GO:0010575//positive regulation of vascular endothelial growth factor production;GO:0048382//mesendoderm development;GO:1900224//positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry;GO:0022409//positive regulation of cell-cell adhesion;GO:0035987//endodermal cell differentiation;GO:0048546//digestive tract morphogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0001944//vasculature development;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0060136//embryonic process involved in female pregnancy;GO:0009880//embryonic pattern specification;GO:0001831//trophectodermal cellular morphogenesis;GO:0048859//formation of anatomical boundary;GO:0032927//positive regulation of activin receptor signaling pathway;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0001889//liver development;GO:0090010//transforming growth factor beta receptor signaling pathway involved in primitive streak formation;GO:0060391//positive regulation of SMAD protein import into nucleus;GO:0060395//SMAD protein signal transduction;GO:0001947//heart looping;GO:0010085//polarity specification of proximal/distal axis;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0010721//negative regulation of cell development;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0050679//positive regulation of epithelial cell proliferation","K04666//nodal","NP_060525.3//nodal homolog isoform 1 preproprotein [Homo sapiens]","1//3;4"]
[4318,2387,0.1,0.1,0,1.01458640875819,"*",0.997882,"MMP9","GO:1904724//tertiary granule lumen;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:1904813//ficolin-1-rich granule lumen;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix","GO:0004252//serine-type endopeptidase activity;GO:0004175//endopeptidase activity;GO:0008237//metallopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0005518//collagen binding;GO:0042802//identical protein binding;GO:0008270//zinc ion binding","GO:0030335//positive regulation of cell migration;GO:0034614//cellular response to reactive oxygen species;GO:0035987//endodermal cell differentiation;GO:0001503//ossification;GO:1904707//positive regulation of vascular smooth muscle cell proliferation;GO:0007566//embryo implantation;GO:0001934//positive regulation of protein phosphorylation;GO:0051549//positive regulation of keratinocyte migration;GO:0043312//neutrophil degranulation;GO:0030225//macrophage differentiation;GO:0045742//positive regulation of epidermal growth factor receptor signaling pathway;GO:0071276//cellular response to cadmium ion;GO:0043388//positive regulation of DNA binding;GO:0050900//leukocyte migration;GO:0048013//ephrin receptor signaling pathway;GO:2001268//negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:1900122//positive regulation of receptor binding;GO:0022617//extracellular matrix disassembly;GO:0006508//proteolysis;GO:2001258//negative regulation of cation channel activity;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0001501//skeletal system development;GO:0030574//collagen catabolic process","K01403//matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]","NP_004985.2//matrix metalloproteinase-9 preproprotein [Homo sapiens]","2//1"]
[79698,2482,0.39,0.39,0,1.02056760002566,"*",0.996098,"ZMAT4","GO:0005634//nucleus;GO:0005622//intracellular","GO:0003723//RNA binding;GO:0003677//DNA binding;GO:0002039//p53 binding;GO:0008270//zinc ion binding;GO:0003676//nucleic acid binding","GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator","K10137//zinc finger, matrin type 3","XP_017817459.1//zinc finger matrin-type protein 4 isoform X1 [Papio anubis];NP_001129203.1//zinc finger matrin-type protein 4 isoform b [Homo sapiens]","1//3;2//1"]
[2196,14565,0.02,0.02,0,1.01452183477597,"*",0.997882,"FAT2","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005913//cell-cell adherens junction;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005509//calcium ion binding","GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0010631//epithelial cell migration","K16506//protocadherin Fat 1/2/3","NP_001438.1//protocadherin Fat 2 precursor [Homo sapiens]","2//1"]
[57633,5976,0.01,0.01,0,0.628729009428033,"*",0.500968,"LRRN1","GO:0005615//extracellular space;GO:0016021//integral component of membrane;GO:0005578//proteinaceous extracellular matrix","NA","GO:0051965//positive regulation of synapse assembly","K12655//OTU domain-containing protein 5 [EC:3.4.19.12];K16351//netrin-G2 ligand","NP_065924.3//leucine-rich repeat neuronal protein 1 precursor [Homo sapiens]","6;1//3"]
[126432,3050,1.72,1.72,0,1.02098860901528,"*",0.99114,"RINL","GO:0001726//ruffle;GO:0031410//cytoplasmic vesicle;GO:0015629//actin cytoskeleton","GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity","GO:0006897//endocytosis;GO:0015031//protein transport","K17638//Ras and Rab interactor 1;K17985//activating molecule in BECN1-regulated autophagy protein 1","NP_001182762.1//ras and Rab interactor-like protein isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[55026,3276,0.05,0.05,0,1.01090415368034,"*",0.998184,"TMEM255A","GO:0016021//integral component of membrane","NA","NA","NA","EAX11888.1//family with sequence similarity 70, member A, isoform CRA_b [Homo sapiens];NP_001098015.1//transmembrane protein 255A isoform 3 [Homo sapiens];EAX11890.1//family with sequence similarity 70, member A, isoform CRA_d [Homo sapiens]","1//3;3//A2MP1"]
[56920,4975,0.05,0.05,0,1.01426362102316,"*",0.997882,"SEMA3G","GO:0070062//extracellular exosome;GO:0005615//extracellular space","GO:0005102//receptor binding;GO:0038191//neuropilin binding","GO:0030517//negative regulation of axon extension;GO:0050919//negative chemotaxis","K06840//semaphorin 3","XP_001172139.2//PREDICTED: semaphorin-3G isoform X2 [Pan troglodytes]","2//1"]
[10170,1589,0.71,0.71,0,1.02093777526792,"*",0.995948,"DHRS9","GO:0031090//organelle membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005789//endoplasmic reticulum membrane","GO:0004022//alcohol dehydrogenase (NAD) activity;GO:0004745//retinol dehydrogenase activity;GO:0047035//testosterone dehydrogenase (NAD+) activity;GO:0016854//racemase and epimerase activity","GO:0042904//9-cis-retinoic acid biosynthetic process;GO:0042448//progesterone metabolic process;GO:0008209//androgen metabolic process;GO:0042572//retinol metabolic process;GO:0030855//epithelial cell differentiation","K11149//dehydrogenase/reductase SDR family member 9 [EC:1.1.-.-]","NP_001276692.1//dehydrogenase/reductase SDR family member 9 isoform 2 [Homo sapiens]","1//3"]
[728586,928,0.09,0.09,0,1.00187210300861,"*",0.998548,"CCDC192","NA","NA","NA","K14000//ribosome-binding protein 1;K16307//serine/threonine-protein kinase MRCK [EC:2.7.11.1]","NP_001304867.1//coiled-coil domain-containing protein 192 [Homo sapiens]","1//3"]
[9901,8977,0.08,0.08,0,1.01969617678709,"*",0.996588,"SRGAP3","GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0048365//Rac GTPase binding;GO:0005096//GTPase activator activity","GO:0007165//signal transduction;GO:0030336//negative regulation of cell migration;GO:0051056//regulation of small GTPase mediated signal transduction","K07526//SLIT-ROBO Rho GTPase activating protein","NP_055665.1//SLIT-ROBO Rho GTPase-activating protein 3 isoform a [Homo sapiens];NP_001028289.1//SLIT-ROBO Rho GTPase-activating protein 3 isoform b [Homo sapiens]","3//A2MP1;2//1"]
[10817,2198,3.1,3.1,0,1.02008741810206,"*",0.989882,"FRS3","NA","NA","NA","K12461//fibroblast growth factor receptor substrate 2","XP_011842079.1//PREDICTED: fibroblast growth factor receptor substrate 3 isoform X1 [Mandrillus leucophaeus]",4]
[128864,586,0.15,0.15,0,1.00149467897281,"*",0.998548,"C20orf144","NA","NA","NA","NA","NP_543015.1//uncharacterized protein C20orf144 [Homo sapiens]","3//A2MP1"]
[92292,2099,0.04,0.04,0,1.00130607357188,"*",0.998548,"GLYATL1","GO:0005739//mitochondrion","GO:0047946//glutamine N-acyltransferase activity;GO:0047961//glycine N-acyltransferase activity","GO:0006541//glutamine metabolic process","K00628//glycine N-acyltransferase / glycine N-benzoyltransferase [EC:2.3.1.13 2.3.1.71]","NP_001207423.1//glycine N-acyltransferase-like protein 1 isoform 2 [Homo sapiens];NP_542392.2//glycine N-acyltransferase-like protein 1 isoform 1 [Homo sapiens]","4;1//3;2//1"]
[58529,1583,0.05,0.05,0,1.00105471017949,"*",0.998548,"MYOZ1","GO:0005634//nucleus;GO:0030018//Z disc;GO:0015629//actin cytoskeleton;GO:0031143//pseudopodium","GO:0003779//actin binding;GO:0051373//FATZ binding;GO:0031433//telethonin binding","GO:0030239//myofibril assembly","K07597//desmoglein 2;K13098//RNA-binding protein FUS","NP_067068.1//myozenin-1 [Homo sapiens]","3//A2MP1"]
[63976,8674,0.04,0.04,0,1.01658063179382,"*",0.997616,"PRDM16","GO:0017053//transcriptional repressor complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016235//aggresome","GO:0046872//metal ion binding;GO:0003713//transcription coactivator activity;GO:0043565//sequence-specific DNA binding;GO:0046332//SMAD binding;GO:0033613//activating transcription factor binding;GO:0018024//histone-lysine N-methyltransferase activity","GO:0045892//negative regulation of transcription, DNA-templated;GO:0050872//white fat cell differentiation;GO:0006351//transcription, DNA-templated;GO:0035019//somatic stem cell population maintenance;GO:0045893//positive regulation of transcription, DNA-templated;GO:0043586//tongue development;GO:0030853//negative regulation of granulocyte differentiation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0022008//neurogenesis;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0043457//regulation of cellular respiration;GO:0050873//brown fat cell differentiation;GO:0060021//palate development;GO:0090336//positive regulation of brown fat cell differentiation","K09228//KRAB domain-containing zinc finger protein;K20688//Rho guanine nucleotide exchange factor 16","NP_955533.2//PR domain zinc finger protein 16 isoform 2 [Homo sapiens];NP_071397.3//PR domain zinc finger protein 16 isoform 1 [Homo sapiens]","3//A2MP1;2//1"]
[10964,5910,0.01,0.01,0,0.625485605127403,"*",0.500968,"IFI44L","GO:0005737//cytoplasm","GO:0005525//GTP binding","GO:0051607//defense response to virus","NA","NP_006811.2//interferon-induced protein 44-like [Homo sapiens]","3//A2MP1"]
[79668,7125,0.15,0.15,0,1.02087226334702,"*",0.995948,"PARP8","GO:0005622//intracellular","GO:0003950//NAD+ ADP-ribosyltransferase activity","NA","K15258//poly [ADP-ribose] polymerase 6/8 [EC:2.4.2.30]","XP_004380507.1//PREDICTED: poly [ADP-ribose] polymerase 8 isoform X3 [Trichechus manatus latirostris];NP_001317957.1//poly [ADP-ribose] polymerase 8 isoform 3 [Homo sapiens];XP_004380505.1//PREDICTED: poly [ADP-ribose] polymerase 8 isoform X1 [Trichechus manatus latirostris];XP_016808811.1//PREDICTED: poly [ADP-ribose] polymerase 8 isoform X2 [Pan troglodytes]","1//3;3//A2MP1"]
[1369,1756,0.05,0.05,0,1.00067790163112,"*",0.998548,"CPN1","GO:0030141//secretory granule;GO:0005615//extracellular space;GO:0005794//Golgi apparatus;GO:0005576//extracellular region;GO:0097060//synaptic membrane;GO:0043025//neuronal cell body","GO:0004185//serine-type carboxypeptidase activity;GO:0008270//zinc ion binding;GO:0004181//metallocarboxypeptidase activity","GO:0010815//bradykinin catabolic process;GO:0030449//regulation of complement activation;GO:0051384//response to glucocorticoid;GO:0030070//insulin processing","K01292//carboxypeptidase N catalytic subunit [EC:3.4.17.3]","NP_001299.1//carboxypeptidase N catalytic chain precursor [Homo sapiens]","2//1"]
[100528064,787,1.95,0.01,-7.60733031374961,{"v":1.91034093567251e-05,"d":"1.91E-05"},"Down",{"v":3.8855e-06,"d":"3.89E-06"},"NEDD8-MDP1","GO:0070062//extracellular exosome","GO:0046872//metal ion binding;GO:0004725//protein tyrosine phosphatase activity","NA","K17619//magnesium-dependent phosphatase 1 [EC:3.1.3.48 3.1.3.-]","NP_001186752.1//NEDD8-MDP1 protein [Homo sapiens]","2//1"]
[333932,507,0.67,0.01,-6.06608919045777,0.227473240490241,"*",0.1254848,"HIST2H3A","NA","NA","NA","K11253//histone H3;K11254//histone H4","XP_008958403.1//PREDICTED: uncharacterized protein LOC100972611 [Pan paniscus]","2//1"]
[8367,377,0.48,0.01,-5.58496250072116,0.390246236383124,"*",0.250726,"HIST1H4E","NA","NA","NA","K11253//histone H3;K11254//histone H4","XP_003804484.2//PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein LOC100980546 [Pan paniscus]","3//A2MP1"]
[8332,470,0.37,0.01,-5.20945336562895,0.390970043342444,"*",0.250726,"HIST1H2AL","NA","NA","NA","K11251//histone H2A;K11254//histone H4","XP_011931511.1//PREDICTED: uncharacterized protein LOC105593202 [Cercocebus atys]","2//1"]
[54979,785,0.32,0.01,-5,0.226701447093418,"*",0.1254848,"HRASLS2","GO:0005829//cytosol;GO:0016021//integral component of membrane","GO:0016746//transferase activity, transferring acyl groups;GO:0016787//hydrolase activity","GO:0036152//phosphatidylethanolamine acyl-chain remodeling;GO:0016042//lipid catabolic process","K16817//HRAS-like suppressor 3 [EC:3.1.1.32 3.1.1.4]","NP_060348.1//HRAS-like suppressor 2 [Homo sapiens]","1//3"]
[727837,1347,0.26,0.01,-4.70043971814109,0.128568283583237,"*",0.0628032,"SSX2B","GO:0005634//nucleus","GO:0003714//transcription corepressor activity;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:1903507//negative regulation of nucleic acid-templated transcription","K15625//protein SSX2;K15624//protein SSX1","XP_011925496.1//PREDICTED: protein SSX2 isoform X2 [Cercocebus atys];NP_003138.3//protein SSX2 isoform a [Homo sapiens];XP_009437384.2//PREDICTED: protein SSX2 isoform X2 [Pan troglodytes]","1//3;2//1"]
[100129216,213,0.24,0.01,-4.58496250072116,1.00084899140797,"*",0.999032,"DEFB131B","GO:0005615//extracellular space;GO:0009986//cell surface;GO:0005576//extracellular region","NA","GO:0002741//positive regulation of cytokine secretion involved in immune response;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0090026//positive regulation of monocyte chemotaxis;GO:0071223//cellular response to lipoteichoic acid;GO:0042742//defense response to bacterium;GO:0032722//positive regulation of chemokine production;GO:0045087//innate immune response","NA","NP_001229782.1//beta-defensin 131B precursor [Homo sapiens]","1//3"]
[65982,2605,0.21,0.01,-4.39231742277876,0.0208810918611987,"*",0.00787322,"ZSCAN18","GO:0005634//nucleus","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0006351//transcription, DNA-templated","K09230//SCAN domain-containing zinc finger protein","NP_001139014.1//zinc finger and SCAN domain-containing protein 18 isoform 1 [Homo sapiens];XP_016882658.1//PREDICTED: zinc finger and SCAN domain-containing protein 18 isoform X3 [Homo sapiens]","4;1//3"]
[1160,1486,0.2,0.01,-4.32192809488736,0.128469498885901,"*",0.0628032,"CKMT2","GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0004111//creatine kinase activity","GO:0006936//muscle contraction;GO:0006600//creatine metabolic process","K00933//creatine kinase [EC:2.7.3.2]","NP_001816.2//creatine kinase S-type, mitochondrial precursor [Homo sapiens]","1//3;2//1"]
[392138,933,0.18,0.01,-4.16992500144231,0.390741182829268,"*",0.250726,"OR2A25","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity","NA","K04257//olfactory receptor","XP_020145275.1//olfactory receptor 2A25 [Microcebus murinus]","1//3"]
[168002,2469,0.49,0.03,-4.02974734339405,0.000553788903790911,"Down",1.472356E-4,"DACT2","GO:0005739//mitochondrion;GO:0005737//cytoplasm","GO:0005080//protein kinase C binding;GO:0051018//protein kinase A binding;GO:0008134//transcription factor binding;GO:0070097//delta-catenin binding;GO:0008013//beta-catenin binding","GO:1900108//negative regulation of nodal signaling pathway;GO:0002244//hematopoietic progenitor cell differentiation;GO:0043588//skin development;GO:0007162//negative regulation of cell adhesion;GO:0003382//epithelial cell morphogenesis;GO:0030111//regulation of Wnt signaling pathway;GO:0072061//inner medullary collecting duct development","K22154//dapper","NP_999627.2//dapper homolog 2 isoform a [Homo sapiens];NP_001273280.1//dapper homolog 2 isoform c [Homo sapiens];XP_011533809.1//PREDICTED: dapper homolog 2 isoform X1 [Homo sapiens]","4;1//3"]
[3957,543,0.16,0.01,-4,0.641325759897419,"*",0.500968,"LGALS2","NA","GO:0030246//carbohydrate binding;GO:0016936//galactoside binding","NA","K10090//galectin-2","NP_006489.1//galectin-2 [Homo sapiens]","2//1"]
[101059918,5172,0.15,0.01,-3.90689059560852,0.00600851514018692,"*",0.00197212,"GOLGA8R","GO:0005794//Golgi apparatus","NA","NA","K20358//golgin subfamily A member 2","NP_001269413.1//golgin subfamily A member 8R [Homo sapiens]","1//3"]
[404203,610,0.14,0.01,-3.8073549220576,0.63968527833733,"*",0.500968,"SPINK6","GO:0005576//extracellular region","GO:0004867//serine-type endopeptidase inhibitor activity","GO:1900004//negative regulation of serine-type endopeptidase activity;GO:0070268//cornification","NA","NP_995313.2//serine protease inhibitor Kazal-type 6 precursor [Homo sapiens]","1//3;3//A2MP1"]
[100129396,1759,0.14,0.01,-3.8073549220576,0.391658236260512,"*",0.250726,"FAM106CP","NA","NA","NA","NA","NP_001335091.1//putative protein FAM106C [Homo sapiens]","1//3"]
[170685,1955,0.13,0.01,-3.70043971814109,0.227344243529545,"*",0.1254848,"NUDT10","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0052841//inositol bisdiphosphate tetrakisphosphate diphosphatase activity;GO:0050072//m7G(5')pppN diphosphatase activity;GO:0052844//inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity;GO:0034431//bis(5'-adenosyl)-hexaphosphatase activity;GO:0016787//hydrolase activity;GO:0008486//diphosphoinositol-polyphosphate diphosphatase activity;GO:0052842//inositol diphosphate pentakisphosphate diphosphatase activity;GO:0052843//inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity;GO:0052845//inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity;GO:0052848//inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity;GO:0052846//inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity;GO:0046872//metal ion binding;GO:0000298//endopolyphosphatase activity;GO:0034432//bis(5'-adenosyl)-pentaphosphatase activity;GO:0052847//inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity;GO:0052840//inositol diphosphate tetrakisphosphate diphosphatase activity","GO:0071543//diphosphoinositol polyphosphate metabolic process;GO:0043647//inositol phosphate metabolic process;GO:1901907//diadenosine pentaphosphate catabolic process;GO:1901911//adenosine 5'-(hexahydrogen pentaphosphate) catabolic process;GO:1901909//diadenosine hexaphosphate catabolic process","K07766//diphosphoinositol-polyphosphate diphosphatase [EC:3.6.1.52]","NP_694853.1//diphosphoinositol polyphosphate phosphohydrolase 3-alpha [Homo sapiens]","1//3;3//A2MP1"]
[26083,685,0.12,0.01,-3.58496250072116,0.640504468704978,"*",0.500968,"TBC1D29","NA","NA","NA","K20134//TBC1 domain family member 3","EAW51237.1//DKFZP434O047 protein, isoform CRA_a [Homo sapiens]","2//1"]
[8712,680,0.12,0.01,-3.58496250072116,0.631607169060773,"*",0.500968,"PAGE1","NA","NA","GO:0006968//cellular defense response","NA","NP_003776.2//P antigen family member 1 [Homo sapiens]","3//A2MP1"]
[2709,1376,0.12,0.01,-3.58496250072116,0.390056206077133,"*",0.250726,"GJB5","GO:0005922//connexin complex;GO:0016021//integral component of membrane","NA","GO:1905867//epididymis development;GO:0008544//epidermis development;GO:0060713//labyrinthine layer morphogenesis;GO:0007154//cell communication;GO:0060708//spongiotrophoblast differentiation;GO:0060707//trophoblast giant cell differentiation","K07624//gap junction beta-5 protein","NP_005259.1//gap junction beta-5 protein [Homo sapiens]","3//A2MP1"]
[4049,1423,0.11,0.01,-3.4594316186373,0.390931881307955,"*",0.250726,"LTA","GO:0016020//membrane;GO:0005615//extracellular space;GO:0005886//plasma membrane","GO:0005164//tumor necrosis factor receptor binding;GO:0005125//cytokine activity;GO:0005102//receptor binding","GO:0060252//positive regulation of glial cell proliferation;GO:0032496//response to lipopolysaccharide;GO:0043065//positive regulation of apoptotic process;GO:0006959//humoral immune response;GO:0007584//response to nutrient;GO:0050830//defense response to Gram-positive bacterium;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0032729//positive regulation of interferon-gamma production;GO:0042493//response to drug;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0048535//lymph node development;GO:0048147//negative regulation of fibroblast proliferation;GO:0006915//apoptotic process;GO:0001666//response to hypoxia;GO:0002876//positive regulation of chronic inflammatory response to antigenic stimulus;GO:0044130//negative regulation of growth of symbiont in host;GO:0002925//positive regulation of humoral immune response mediated by circulating immunoglobulin","K05468//lymphotoxin alpha (TNF superfamily, member 1)","NP_000586.2//lymphotoxin-alpha precursor [Homo sapiens]","3//A2MP1;2//1"]
[1117,1456,0.11,0.01,-3.4594316186373,0.390855579584269,"*",0.250726,"CHI3L2","GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0030246//carbohydrate binding;GO:0016787//hydrolase activity;GO:0008061//chitin binding","GO:0005975//carbohydrate metabolic process","K17523//chitinase-3-like protein 1/2","AAB04534.1//chitinase, partial [Homo sapiens];EAW56480.1//chitinase 3-like 2, isoform CRA_a [Homo sapiens]","1//3;2//1"]
[54511,2385,0.1,0.01,-3.32192809488736,0.227421624143408,"*",0.1254848,"HMGCLL1","GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005789//endoplasmic reticulum membrane;GO:0048471//perinuclear region of cytoplasm","GO:0046872//metal ion binding;GO:0004419//hydroxymethylglutaryl-CoA lyase activity","GO:0046951//ketone body biosynthetic process","K01640//hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4]","XP_016811172.1//PREDICTED: 3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic isoform X2 [Pan troglodytes];NP_001274682.1//3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic isoform e [Homo sapiens];NP_061909.2//3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic isoform a [Homo sapiens];NP_001274670.1//3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic isoform c [Homo sapiens];XP_004416094.2//PREDICTED: LOW QUALITY PROTEIN: 3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic [Odobenus rosmarus divergens]","1//3;2//1"]
[6123,1547,0.1,0.01,-3.32192809488736,0.390664955520874,"*",0.250726,"RPL3L","GO:0005840//ribosome;GO:0016020//membrane;GO:0022625//cytosolic large ribosomal subunit","GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome","GO:0006412//translation;GO:0000027//ribosomal large subunit assembly","K02925//large subunit ribosomal protein L3e","NP_005052.1//60S ribosomal protein L3-like [Homo sapiens]","2//1"]
[51237,845,0.1,0.01,-3.32192809488736,0.628087499568323,"*",0.500968,"MZB1","GO:0005788//endoplasmic reticulum lumen;GO:0034663//endoplasmic reticulum chaperone complex;GO:0005576//extracellular region;GO:0005737//cytoplasm","NA","GO:0030888//regulation of B cell proliferation;GO:0042127//regulation of cell proliferation;GO:0002642//positive regulation of immunoglobulin biosynthetic process;GO:2001274//negative regulation of glucose import in response to insulin stimulus;GO:0033622//integrin activation;GO:0008284//positive regulation of cell proliferation;GO:0006915//apoptotic process","K14611//solute carrier family 23 (nucleobase transporter), member 1/2;K15410//elongation factor 1-delta","XP_001172512.2//PREDICTED: marginal zone B- and B1-cell-specific protein [Pan troglodytes]","3//A2MP1"]
[55753,3292,0.19,0.02,-3.24792751344359,0.0299403102916931,"*",0.01182318,"OGDHL","NA","GO:0004591//oxoglutarate dehydrogenase (succinyl-transferring) activity;GO:0030976//thiamine pyrophosphate binding","GO:0006099//tricarboxylic acid cycle","K00164//2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]","XP_012891653.1//PREDICTED: 2-oxoglutarate dehydrogenase-like, mitochondrial isoform X3 [Dipodomys ordii];XP_005900672.1//PREDICTED: 2-oxoglutarate dehydrogenase-like, mitochondrial [Bos mutus];XP_014199185.1//PREDICTED: 2-oxoglutarate dehydrogenase-like, mitochondrial isoform X1 [Pan paniscus];NP_001334752.1//2-oxoglutarate dehydrogenase-like, mitochondrial isoform d [Homo sapiens]","1//3;2//1"]
[728591,1115,0.09,0.01,-3.16992500144231,0.632305849557522,"*",0.500968,"CCDC169","NA","NA","NA","K14000//ribosome-binding protein 1","XP_004054424.2//PREDICTED: coiled-coil domain-containing protein 169 isoform X1 [Gorilla gorilla gorilla];NP_001138456.1//coiled-coil domain-containing protein 169 isoform c [Homo sapiens];XP_004054425.1//PREDICTED: coiled-coil domain-containing protein 169 isoform X2 [Gorilla gorilla gorilla];NP_001185837.1//coiled-coil domain-containing protein 169 isoform e [Homo sapiens];NP_001138453.1//coiled-coil domain-containing protein 169 isoform a [Homo sapiens]","1//3;2//1"]
[441669,942,0.09,0.01,-3.16992500144231,0.63026406489722,"*",0.500968,"OR4Q3","NA","NA","NA","K04257//olfactory receptor","XP_009247105.1//PREDICTED: LOW QUALITY PROTEIN: olfactory receptor 4Q3 [Pongo abelii]","1//3"]
[441531,1678,0.09,0.01,-3.16992500144231,0.627348920664785,"*",0.500968,"PGAM4","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0097228//sperm principal piece","GO:0004619//phosphoglycerate mutase activity;GO:0016787//hydrolase activity;GO:0004082//bisphosphoglycerate mutase activity;GO:0046538//2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity","GO:0006094//gluconeogenesis;GO:1902093//positive regulation of flagellated sperm motility;GO:0006096//glycolytic process;GO:0043456//regulation of pentose-phosphate shunt","K01834//2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]","NP_001025062.1//phosphoglycerate mutase 4 [Homo sapiens]","2//1"]
[64919,7828,0.35,0.04,-3.12928301694497,{"v":6.57936267340591e-07,"d":"6.58E-07"},"Down",{"v":1.059354E-7,"d":"1.06E-07"},"BCL11B","GO:0005634//nucleus;GO:0043005//neuron projection","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0043565//sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0003676//nucleic acid binding","GO:0021773//striatal medium spiny neuron differentiation;GO:0010837//regulation of keratinocyte proliferation;GO:0033077//T cell differentiation in thymus;GO:0035701//hematopoietic stem cell migration;GO:0003334//keratinocyte development;GO:0022008//neurogenesis;GO:0021902//commitment of neuronal cell to specific neuron type in forebrain;GO:0019216//regulation of lipid metabolic process;GO:0008285//negative regulation of cell proliferation;GO:0097535//lymphoid lineage cell migration into thymus;GO:0046632//alpha-beta T cell differentiation;GO:0007165//signal transduction;GO:0003382//epithelial cell morphogenesis;GO:0048538//thymus development;GO:0043066//negative regulation of apoptotic process;GO:0045664//regulation of neuron differentiation;GO:0043368//positive T cell selection;GO:0042475//odontogenesis of dentin-containing tooth;GO:0071678//olfactory bulb axon guidance;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0031077//post-embryonic camera-type eye development;GO:0033153//T cell receptor V(D)J recombination","K22046//B-cell lymphoma/leukemia 11B","NP_612808.1//B-cell lymphoma/leukemia 11B isoform 1 [Homo sapiens];NP_001269166.1//B-cell lymphoma/leukemia 11B isoform 3 [Homo sapiens];NP_075049.1//B-cell lymphoma/leukemia 11B isoform 2 [Homo sapiens];NP_001269167.1//B-cell lymphoma/leukemia 11B isoform 4 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[56751,1907,0.08,0.01,-3,0.393350729129837,"*",0.250726,"BARHL1","GO:0005634//nucleus","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0001764//neuron migration;GO:0030901//midbrain development;GO:0006355//regulation of transcription, DNA-templated;GO:0007605//sensory perception of sound;GO:0043524//negative regulation of neuron apoptotic process","K09360//BarH-like","EDL08401.1//BarH-like 1 (Drosophila), isoform CRA_b, partial [Mus musculus]","3//A2MP1"]
[390882,1038,0.08,0.01,-3,0.635418678100683,"*",0.500968,"OR7G2","NA","NA","NA","K04257//olfactory receptor","XP_012364869.1//PREDICTED: LOW QUALITY PROTEIN: olfactory receptor 7G2-like [Nomascus leucogenys]","1//3"]
[359787,1079,0.08,0.01,-3,0.633306650205761,"*",0.500968,"DPPA3","GO:0005634//nucleus;GO:0001939//female pronucleus;GO:0001940//male pronucleus;GO:0005737//cytoplasm","GO:0035064//methylated histone binding","GO:1901536//negative regulation of DNA demethylation;GO:0040016//embryonic cleavage;GO:0044726//protection of DNA demethylation of female pronucleus;GO:0016569//covalent chromatin modification;GO:2000653//regulation of genetic imprinting","NA","NP_954980.1//developmental pluripotency-associated protein 3 [Homo sapiens]","3//A2MP1"]
[51127,1932,0.08,0.01,-3,0.391046389767624,"*",0.250726,"TRIM17","GO:0005622//intracellular","GO:0030674//protein binding, bridging;GO:0008270//zinc ion binding;GO:0004842//ubiquitin-protein transferase activity","GO:0032880//regulation of protein localization;GO:0051865//protein autoubiquitination;GO:0006914//autophagy","K12007//tripartite motif-containing protein 17 [EC:2.3.2.27]","NP_057186.1//E3 ubiquitin-protein ligase TRIM17 isoform 1 [Homo sapiens];NP_001128327.1//E3 ubiquitin-protein ligase TRIM17 isoform 3 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[106821730,3816,0.15,0.02,-2.90689059560852,0.141492115301778,"*",0.0707372,"BUB1B-PAK6","GO:0005634//nucleus;GO:0001650//fibrillar center;GO:0030054//cell junction;GO:0005737//cytoplasm","GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0048365//Rac GTPase binding;GO:0045296//cadherin binding","GO:0023014//signal transduction by protein phosphorylation;GO:0016477//cell migration;GO:0007346//regulation of mitotic cell cycle;GO:0030036//actin cytoskeleton organization;GO:0006355//regulation of transcription, DNA-templated;GO:0032147//activation of protein kinase activity;GO:0007612//learning;GO:0043408//regulation of MAPK cascade;GO:0006915//apoptotic process;GO:0007613//memory;GO:0007626//locomotory behavior;GO:0007266//Rho protein signal transduction;GO:0007010//cytoskeleton organization;GO:0031098//stress-activated protein kinase signaling cascade;GO:0042981//regulation of apoptotic process","K05735//p21-activated kinase 6 [EC:2.7.11.1]","NP_064553.1//serine/threonine-protein kinase PAK 6 isoform 1 [Homo sapiens]","2//1"]
[100131539,3441,0.07,0.01,-2.8073549220576,0.227524880272418,"*",0.1254848,"ZNF705E","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_004452775.1//PREDICTED: zinc finger protein 596-like isoform X1 [Dasypus novemcinctus]","1//3"]
[80217,5395,0.07,0.01,-2.8073549220576,0.0709073249541025,"*",0.031432,"CFAP43","GO:0042995//cell projection","NA","NA","K10388//plectin;K20478//golgin subfamily B member 1","NP_079421.5//cilia- and flagella-associated protein 43 [Homo sapiens]",6]
[7007,6468,0.07,0.01,-2.8073549220576,0.0384060076845484,"*",0.01573122,"TECTA","GO:0070062//extracellular exosome;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0031225//anchored component of membrane;GO:0005578//proteinaceous extracellular matrix","GO:0005201//extracellular matrix structural constituent","GO:0007160//cell-matrix adhesion;GO:0006501//C-terminal protein lipidation;GO:0007605//sensory perception of sound","K18273//alpha-tectorin","NP_005413.2//alpha-tectorin precursor [Homo sapiens]","2//1"]
[1823,4271,0.21,0.03,-2.8073549220576,0.00999284618504436,"*",0.00345502,"DSC1","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005921//gap junction;GO:0101003//ficolin-1-rich granule membrane;GO:0001533//cornified envelope;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0030057//desmosome","GO:0005509//calcium ion binding","GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0043312//neutrophil degranulation;GO:0031424//keratinization;GO:0070268//cornification","K07600//desmocollin 1","NP_077739.1//desmocollin-1 isoform Dsc1a preproprotein [Homo sapiens];NP_004939.1//desmocollin-1 isoform Dsc1b precursor [Homo sapiens]","3//A2MP1;2//1"]
[6662,3963,3.9,0.6,-2.70043971814109,{"v":1.94174356681614e-29,"d":"1.94E-29"},"Down",{"v":5.42142E-31,"d":"5.42E-31"},"SOX9","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0043234//protein complex;GO:0044798//nuclear transcription factor complex","GO:0001046//core promoter sequence-specific DNA binding;GO:0043425//bHLH transcription factor binding;GO:0003682//chromatin binding;GO:0001158//enhancer sequence-specific DNA binding;GO:0035326//enhancer binding;GO:0008013//beta-catenin binding","GO:0060532//bronchus cartilage development;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0001708//cell fate specification;GO:0001502//cartilage condensation;GO:0051216//cartilage development;GO:0060018//astrocyte fate commitment;GO:0019933//cAMP-mediated signaling","K18435//transcription factor SOX9 (SOX group E)","BAD90382.1//mKIAA4243 protein, partial [Mus musculus]","3//A2MP1"]
[56130,3061,0.37,0.06,-2.62449086490779,0.0071280456167979,"*",2.38018E-3,"PCDHB6","GO:0005887//integral component of plasma membrane","GO:0042802//identical protein binding;GO:0005509//calcium ion binding","GO:0007416//synapse assembly;GO:0009988//cell-cell recognition;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007268//chemical synaptic transmission","K16494//protocadherin beta","NP_001013027.1//protocadherin beta-6 precursor [Pan troglodytes];XP_012360027.1//PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein LOC100585730 [Nomascus leucogenys]","1//3;3//A2MP1"]
[33,2565,0.06,0.01,-2.58496250072116,0.393119073812328,"*",0.250726,"ACADL","GO:0005759//mitochondrial matrix;GO:0031966//mitochondrial membrane","GO:0004466//long-chain-acyl-CoA dehydrogenase activity;GO:0016401//palmitoyl-CoA oxidase activity;GO:0050660//flavin adenine dinucleotide binding;GO:0000062//fatty-acyl-CoA binding;GO:0003995//acyl-CoA dehydrogenase activity","GO:0001659//temperature homeostasis;GO:0033539//fatty acid beta-oxidation using acyl-CoA dehydrogenase;GO:0051289//protein homotetramerization;GO:0055114//oxidation-reduction process;GO:0046322//negative regulation of fatty acid oxidation;GO:0042758//long-chain fatty acid catabolic process;GO:0044242//cellular lipid catabolic process;GO:0006635//fatty acid beta-oxidation;GO:0090181//regulation of cholesterol metabolic process;GO:0045717//negative regulation of fatty acid biosynthetic process;GO:0042413//carnitine catabolic process;GO:0019254//carnitine metabolic process, CoA-linked","K00255//long-chain-acyl-CoA dehydrogenase [EC:1.3.8.8]","XP_516063.3//PREDICTED: long-chain specific acyl-CoA dehydrogenase, mitochondrial isoform X1 [Pan troglodytes]","3//A2MP1"]
[862,7284,0.06,0.01,-2.58496250072116,0.226668425931782,"*",0.1256368,"RUNX1T1","GO:0005654//nucleoplasm;GO:0016363//nuclear matrix","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0003700//DNA binding transcription factor activity","GO:0045892//negative regulation of transcription, DNA-templated;GO:0006091//generation of precursor metabolites and energy;GO:0006351//transcription, DNA-templated;GO:0045599//negative regulation of fat cell differentiation","K10053//runt-related transcription factor 1; translocated to, 1","XP_012605070.1//protein CBFA2T1 isoform X4 [Microcebus murinus];XP_011792448.1//PREDICTED: LOW QUALITY PROTEIN: protein CBFA2T1 [Colobus angolensis palliatus];XP_014315183.1//PREDICTED: protein CBFA2T1 isoform X1 [Myotis lucifugus];XP_008253946.1//PREDICTED: LOW QUALITY PROTEIN: protein CBFA2T1 [Oryctolagus cuniculus];XP_012373560.1//PREDICTED: protein CBFA2T1 isoform X1 [Dasypus novemcinctus];XP_016869419.1//PREDICTED: protein CBFA2T1 isoform X1 [Homo sapiens];XP_012373561.1//PREDICTED: protein CBFA2T1 isoform X3 [Dasypus novemcinctus]","1//3;3//A2MP1;2//1"]
[793,2551,0.06,0.01,-2.58496250072116,0.391849831131983,"*",0.250726,"CALB1","GO:0070062//extracellular exosome;GO:0030425//dendrite;GO:0030424//axon;GO:0005634//nucleus;GO:0043195//terminal bouton;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0005829//cytosol;GO:0043197//dendritic spine;GO:0045202//synapse","GO:0005499//vitamin D binding;GO:0005509//calcium ion binding;GO:0008270//zinc ion binding","GO:0099509//regulation of presynaptic cytosolic calcium ion concentration;GO:1900271//regulation of long-term synaptic potentiation;GO:0055074//calcium ion homeostasis;GO:0010842//retina layer formation;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0007616//long-term memory;GO:0071310//cellular response to organic substance;GO:0044267//cellular protein metabolic process;GO:0035502//metanephric part of ureteric bud development;GO:0007626//locomotory behavior;GO:0072205//metanephric collecting duct development;GO:0072221//metanephric distal convoluted tubule development;GO:0007614//short-term memory;GO:0072286//metanephric connecting tubule development","K14757//calbindin D28","NP_004920.1//calbindin [Homo sapiens]","3//A2MP1"]
[7078,5496,0.06,0.01,-2.58496250072116,0.357462188264059,"*",0.21966,"TIMP3","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix;GO:0005604//basement membrane","GO:0002020//protease binding;GO:0008191//metalloendopeptidase inhibitor activity;GO:0008270//zinc ion binding","GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:1903984//positive regulation of TRAIL-activated apoptotic signaling pathway;GO:0010033//response to organic substance;GO:0043086//negative regulation of catalytic activity;GO:0051045//negative regulation of membrane protein ectodomain proteolysis;GO:1904684//negative regulation of metalloendopeptidase activity;GO:0071310//cellular response to organic substance","K16866//metalloproteinase inhibitor 3","XP_003258172.1//PREDICTED: metalloproteinase inhibitor 3 isoform X1 [Nomascus leucogenys]",4]
[728747,3517,0.06,0.01,-2.58496250072116,0.390284264665757,"*",0.250726,"ANKRD20A4","GO:0005886//plasma membrane","NA","NA","K17299//POTE ankyrin domain family protein","NP_001092275.1//ankyrin repeat domain-containing protein 20A4 [Homo sapiens]","1//3"]
[786,1327,0.06,0.01,-2.58496250072116,0.625094737697235,"*",0.500968,"CACNG1","GO:0005886//plasma membrane;GO:0005891//voltage-gated calcium channel complex","GO:0005245//voltage-gated calcium channel activity","GO:0006810//transport;GO:0070296//sarcoplasmic reticulum calcium ion transport;GO:0061337//cardiac conduction;GO:0006936//muscle contraction","K04866//voltage-dependent calcium channel gamma-1","NP_000718.1//voltage-dependent calcium channel gamma-1 subunit [Homo sapiens]","3//A2MP1"]
[100533178,878,0.55,0.1,-2.4594316186373,0.226591649904031,"*",0.1256368,"PRORY","NA","NA","NA","NA","NP_001269400.1//proline-rich protein, Y-linked [Homo sapiens]","1//3"]
[374403,1752,0.26,0.05,-2.37851162325373,0.226847772487849,"*",0.1256368,"TBC1D10C","GO:0016020//membrane;GO:0012505//endomembrane system;GO:0101003//ficolin-1-rich granule membrane;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005886//plasma membrane;GO:0031527//filopodium membrane","GO:0017137//Rab GTPase binding;GO:0005096//GTPase activator activity","GO:0051534//negative regulation of NFAT protein import into nucleus;GO:0090630//activation of GTPase activity;GO:0042147//retrograde transport, endosome to Golgi;GO:0006886//intracellular protein transport;GO:0050869//negative regulation of B cell activation;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0043312//neutrophil degranulation;GO:0031338//regulation of vesicle fusion","K19944//TBC1 domain family member 10","NP_940919.1//carabin isoform 1 [Homo sapiens];XP_012351390.1//PREDICTED: carabin isoform X2 [Nomascus leucogenys]","1//3;3//A2MP1"]
[729747,1762,0.05,0.01,-2.32192809488736,0.64096618598318,"*",0.500968,"ZNF878","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_007993536.1//PREDICTED: zinc finger protein 433-like isoform X2 [Chlorocebus sabaeus]","2//1"]
[345630,1572,0.05,0.01,-2.32192809488736,0.637595636363636,"*",0.500968,"FBLL1","NA","NA","NA","K14563//rRNA 2'-O-methyltransferase fibrillarin [EC:2.1.1.-]","NP_001342203.1//rRNA/tRNA 2'-O-methyltransferase fibrillarin-like protein 1 [Homo sapiens]","1//3"]
[84660,3228,0.05,0.01,-2.32192809488736,0.392425742112483,"*",0.250726,"CCDC62","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0030331//estrogen receptor binding;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity","GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0071392//cellular response to estradiol stimulus","K16464//centrosomal protein CEP250;K20040//huntingtin-interacting protein 1-related protein;K12478//early endosome antigen 1","NP_958843.2//coiled-coil domain-containing protein 62 [Homo sapiens]",4]
[2900,3057,0.05,0.01,-2.32192809488736,0.392041613547377,"*",0.250726,"GRIK4","GO:0032983//kainate selective glutamate receptor complex;GO:0042734//presynaptic membrane;GO:0030054//cell junction;GO:0045211//postsynaptic membrane","GO:0004970//ionotropic glutamate receptor activity;GO:0005234//extracellularly glutamate-gated ion channel activity","NA","K05204//glutamate receptor, ionotropic kainate 4","XP_011782368.1//PREDICTED: glutamate receptor ionotropic, kainate 4 [Colobus angolensis palliatus];XP_853030.3//glutamate receptor ionotropic, kainate 4 [Canis lupus familiaris]","4;2//1"]
[6097,3084,0.05,0.01,-2.32192809488736,0.391581650762612,"*",0.250726,"RORC","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body","GO:0003707//steroid hormone receptor activity;GO:0098531//transcription factor activity, direct ligand regulated sequence-specific DNA binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:0004879//nuclear receptor activity;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0008270//zinc ion binding;GO:0008142//oxysterol binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0036315//cellular response to sterol;GO:0045893//positive regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0019218//regulation of steroid metabolic process;GO:0048541//Peyer's patch development;GO:0010906//regulation of glucose metabolic process;GO:0032922//circadian regulation of gene expression;GO:0007623//circadian rhythm;GO:0045598//regulation of fat cell differentiation;GO:0072539//T-helper 17 cell differentiation;GO:0006805//xenobiotic metabolic process;GO:0006351//transcription, DNA-templated;GO:0048535//lymph node development;GO:0060612//adipose tissue development;GO:0042093//T-helper cell differentiation;GO:0070244//negative regulation of thymocyte apoptotic process;GO:0042753//positive regulation of circadian rhythm;GO:0060850//regulation of transcription involved in cell fate commitment;GO:0006367//transcription initiation from RNA polymerase II promoter","K08534//RAR-related orphan receptor gamma","NP_001001523.1//nuclear receptor ROR-gamma isoform b [Homo sapiens];EAW53405.1//RAR-related orphan receptor C, isoform CRA_a [Homo sapiens]","1//3;3//A2MP1"]
[2047,4691,0.05,0.01,-2.32192809488736,0.227138152430595,"*",0.1254848,"EPHB1","GO:0070062//extracellular exosome;GO:0030424//axon;GO:0005783//endoplasmic reticulum;GO:0032433//filopodium tip;GO:0031901//early endosome membrane;GO:0005887//integral component of plasma membrane;GO:0045121//membrane raft;GO:0005829//cytosol","GO:0005524//ATP binding;GO:0008046//axon guidance receptor activity;GO:0005005//transmembrane-ephrin receptor activity;GO:0032403//protein complex binding","GO:0031290//retinal ganglion cell axon guidance;GO:0051965//positive regulation of synapse assembly;GO:0048593//camera-type eye morphogenesis;GO:0060997//dendritic spine morphogenesis;GO:0014719//skeletal muscle satellite cell activation;GO:0060326//cell chemotaxis;GO:0050965//detection of temperature stimulus involved in sensory perception of pain;GO:0021631//optic nerve morphogenesis;GO:0061351//neural precursor cell proliferation;GO:0001525//angiogenesis;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0031589//cell-substrate adhesion;GO:1902723//negative regulation of skeletal muscle satellite cell proliferation;GO:0046777//protein autophosphorylation;GO:0030010//establishment of cell polarity;GO:0021952//central nervous system projection neuron axonogenesis;GO:1902725//negative regulation of satellite cell differentiation;GO:1901214//regulation of neuron death;GO:0046328//regulation of JNK cascade","K05110//Eph receptor B1 [EC:2.7.10.1]","NP_001179758.2//ephrin type-B receptor 1 precursor [Bos taurus]",4]
[23566,1738,0.05,0.01,-2.32192809488736,0.628976093059813,"*",0.500968,"LPAR3","GO:0030424//axon;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0070915//lysophosphatidic acid receptor activity;GO:0008289//lipid binding;GO:0001965//G-protein alpha-subunit binding;GO:0005543//phospholipid binding;GO:0004930//G-protein coupled receptor activity","GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway;GO:0032060//bleb assembly;GO:0000187//activation of MAPK activity;GO:0007268//chemical synaptic transmission;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0048672//positive regulation of collateral sprouting;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0051928//positive regulation of calcium ion transport","K04294//lysophosphatidic acid receptor 3","NP_036284.1//lysophosphatidic acid receptor 3 [Homo sapiens]","2//1"]
[2078,4256,0.05,0.01,-2.32192809488736,0.390170202045787,"*",0.250726,"ERG","GO:0005634//nucleus;GO:0030529//intracellular ribonucleoprotein complex;GO:0005737//cytoplasm","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0043565//sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0004871//signal transducer activity;GO:0003700//DNA binding transcription factor activity","GO:0003197//endocardial cushion development;GO:0016477//cell migration;GO:0007165//signal transduction;GO:0030154//cell differentiation;GO:2000504//positive regulation of blood vessel remodeling;GO:0006468//protein phosphorylation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0007275//multicellular organism development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0003199//endocardial cushion to mesenchymal transition involved in heart valve formation","K09435//transcriptional regulator ERG","XP_017381745.1//PREDICTED: transcriptional regulator ERG isoform X2 [Cebus capucinus imitator];NP_001278320.1//transcriptional regulator ERG isoform 7 [Homo sapiens];NP_891548.1//transcriptional regulator ERG isoform 1 [Homo sapiens];NP_001129626.1//transcriptional regulator ERG isoform 3 [Homo sapiens];NP_004440.1//transcriptional regulator ERG isoform 2 [Homo sapiens];NP_001230361.1//transcriptional regulator ERG isoform 6 [Homo sapiens];NP_001317954.1//transcriptional regulator ERG isoform 8 [Homo sapiens]","4;1//3;3//A2MP1;2//1"]
[56141,5221,0.05,0.01,-2.32192809488736,0.226752737013575,"*",0.1254848,"PCDHA7","NA","NA","NA","K16493//protocadherin alpha","XP_012360377.1//PREDICTED: protocadherin alpha-7 isoform X13 [Nomascus leucogenys]","1//3;2//1"]
[148418,1418,0.29,0.06,-2.27301849440642,0.226438253774117,"*",0.1256368,"SAMD13","NA","NA","NA","K11458//polyhomeotic-like protein 3;K11457//polyhomeotic-like protein 2","XP_005542946.1//PREDICTED: sterile alpha motif domain-containing protein 13 isoform X3 [Macaca fascicularis];XP_005542945.1//PREDICTED: sterile alpha motif domain-containing protein 13 isoform X2 [Macaca fascicularis];XP_019269720.1//PREDICTED: sterile alpha motif domain-containing protein 13 [Panthera pardus]","1//3;2//1"]
[3975,3428,2.06,0.44,-2.22706890854592,{"v":3.49183858064516e-11,"d":"3.49E-11"},"Down",{"v":3.32046e-12,"d":"3.32E-12"},"LHX1","GO:0005634//nucleus;GO:0043234//protein complex;GO:0005622//intracellular","GO:0046872//metal ion binding;GO:0003714//transcription corepressor activity;GO:0001158//enhancer sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0072050//S-shaped body morphogenesis;GO:0060065//uterus development;GO:0001705//ectoderm formation;GO:0010842//retina layer formation;GO:0021937//cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation;GO:0060067//cervix development;GO:0072049//comma-shaped body morphogenesis;GO:0048793//pronephros development;GO:0035847//uterine epithelium development;GO:0021537//telencephalon development;GO:0009953//dorsal/ventral pattern formation;GO:0048703//embryonic viscerocranium morphogenesis;GO:0060322//head development;GO:2000768//positive regulation of nephron tubule epithelial cell differentiation;GO:0061205//paramesonephric duct development;GO:0010468//regulation of gene expression;GO:0060429//epithelium development;GO:0032525//somite rostral/caudal axis specification;GO:0097477//lateral motor column neuron migration;GO:0060068//vagina development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0035502//metanephric part of ureteric bud development;GO:0090009//primitive streak formation;GO:0060066//oviduct development;GO:0021549//cerebellum development;GO:0001655//urogenital system development;GO:0007267//cell-cell signaling;GO:0021871//forebrain regionalization;GO:0009887//animal organ morphogenesis;GO:0040019//positive regulation of embryonic development;GO:0035852//horizontal cell localization;GO:0021527//spinal cord association neuron differentiation;GO:0035849//nephric duct elongation;GO:0007389//pattern specification process;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0009791//post-embryonic development;GO:0072177//mesonephric duct development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0009653//anatomical structure morphogenesis;GO:0001702//gastrulation with mouth forming second;GO:0008045//motor neuron axon guidance;GO:0072278//metanephric comma-shaped body morphogenesis;GO:0090190//positive regulation of branching involved in ureteric bud morphogenesis;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0072283//metanephric renal vesicle morphogenesis;GO:0072178//nephric duct morphogenesis;GO:0009952//anterior/posterior pattern specification;GO:0001822//kidney development;GO:0006355//regulation of transcription, DNA-templated;GO:0001706//endoderm formation;GO:2000744//positive regulation of anterior head development;GO:0009880//embryonic pattern specification;GO:0072077//renal vesicle morphogenesis;GO:0035846//oviduct epithelium development;GO:0072224//metanephric glomerulus development;GO:2000543//positive regulation of gastrulation;GO:0072284//metanephric S-shaped body morphogenesis;GO:0021517//ventral spinal cord development;GO:0060059//embryonic retina morphogenesis in camera-type eye;GO:0006366//transcription from RNA polymerase II promoter;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0021702//cerebellar Purkinje cell differentiation;GO:0009948//anterior/posterior axis specification;GO:0001657//ureteric bud development","K09372//LIM homeobox protein 1","NP_005559.2//LIM/homeobox protein Lhx1 [Homo sapiens]",4]
[25790,1836,0.18,0.04,-2.16992500144231,0.35786321672616,"*",0.21966,"CFAP45","GO:0005929//cilium;GO:0005634//nucleus;GO:0005654//nucleoplasm","NA","NA","K12484//Rab11 family-interacting protein 1/2/5;K12875//apoptotic chromatin condensation inducer in the nucleus;K18626//trichohyalin","NP_036469.2//cilia- and flagella-associated protein 45 [Homo sapiens]","2//1"]
[286436,1893,0.17,0.04,-2.08746284125034,0.357680819571865,"*",0.21966,"H2BFM","GO:0005634//nucleus;GO:0000786//nucleosome","GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity","GO:0006334//nucleosome assembly","K11252//histone H2B","NP_001157888.1//histone H2B type F-M [Homo sapiens]","1//3"]
[116969,1484,0.21,0.05,-2.0703893278914,0.357535035663338,"*",0.21966,"ART5","GO:0016020//membrane;GO:0005576//extracellular region","GO:0003953//NAD+ nucleosidase activity;GO:0003950//NAD+ ADP-ribosyltransferase activity;GO:0003956//NAD(P)+-protein-arginine ADP-ribosyltransferase activity","GO:0006471//protein ADP-ribosylation","K19977//ADP-ribosyltransferase 5 [EC:2.4.2.31]","XP_015290901.1//PREDICTED: ecto-ADP-ribosyltransferase 5 isoform X18 [Macaca fascicularis];XP_001157391.2//PREDICTED: ecto-ADP-ribosyltransferase 5 isoform X3 [Pan troglodytes];XP_008018169.1//PREDICTED: ecto-ADP-ribosyltransferase 5 isoform X2 [Chlorocebus sabaeus]","4;1//3"]
[646960,2158,0.04,0.01,-2,0.641017528997116,"*",0.500968,"PRSS56","GO:0005783//endoplasmic reticulum","GO:0004252//serine-type endopeptidase activity","GO:0006508//proteolysis;GO:0043010//camera-type eye development","K09640//transmembrane protease serine 9 [EC:3.4.21.-]","NP_001182058.1//serine protease 56 precursor [Homo sapiens]","1//3"]
[27283,1804,0.04,0.01,-2,0.639378621923937,"*",0.500968,"TINAG","GO:0043231//intracellular membrane-bounded organelle;GO:0005615//extracellular space;GO:0005604//basement membrane","GO:0008234//cysteine-type peptidase activity;GO:0005044//scavenger receptor activity;GO:0030247//polysaccharide binding;GO:0000166//nucleotide binding;GO:0004197//cysteine-type endopeptidase activity","GO:0007155//cell adhesion;GO:0006955//immune response","K01363//cathepsin B [EC:3.4.22.1]","NP_055279.3//tubulointerstitial nephritis antigen [Homo sapiens]","3//A2MP1"]
[100505679,498,1.4,0.35,-2,0.133131885772101,"*",0.0658992,"UBE2Q2L","NA","NA","NA","K10582//ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]","NP_001230460.1//putative ubiquitin-conjugating enzyme E2Q2-like protein [Homo sapiens]","1//3"]
[3766,5323,0.04,0.01,-2,0.392618088814822,"*",0.250726,"KCNJ10","NA","NA","NA","K05003//potassium inwardly-rectifying channel subfamily J member 10","XP_007974716.1//PREDICTED: ATP-sensitive inward rectifier potassium channel 10 isoform X1 [Chlorocebus sabaeus]",4]
[54346,2006,0.04,0.01,-2,0.635317785963798,"*",0.500968,"UNC93A","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","NA","NA","K16600//tubulin polyglutamylase TTLL2 [EC:6.-.-.-]","NP_061847.2//protein unc-93 homolog A isoform 1 [Homo sapiens];NP_001137419.1//protein unc-93 homolog A isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[5652,1889,0.04,0.01,-2,0.634612437113402,"*",0.500968,"PRSS8","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0046658//anchored component of plasma membrane;GO:0005886//plasma membrane;GO:0019897//extrinsic component of plasma membrane","GO:0004252//serine-type endopeptidase activity;GO:0004175//endopeptidase activity;GO:0017080//sodium channel regulator activity;GO:0008236//serine-type peptidase activity","GO:0010765//positive regulation of sodium ion transport;GO:0070268//cornification","K08664//prostasin [EC:3.4.21.-];K09630//polyserase 2 [EC:3.4.21.-]","NP_002764.1//prostasin preproprotein [Homo sapiens]",4]
[93979,1884,0.04,0.01,-2,0.632255892549577,"*",0.500968,"CPA5","NA","NA","NA","K08781//carboxypeptidase A5 [EC:3.4.17.1]","XP_018886130.1//PREDICTED: carboxypeptidase A5 [Gorilla gorilla gorilla];XP_009452329.1//PREDICTED: carboxypeptidase A5 isoform X2 [Pan troglodytes]","4;1//3"]
[1549,2128,0.04,0.01,-2,0.630661425801876,"*",0.500968,"CYP2A7","NA","GO:0020037//heme binding;GO:0005506//iron ion binding;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen","NA","K17684//cytochrome P450 family 2 subfamily A polypeptide 7 [EC:1.14.14.1];K17685//cytochrome P450 family 2 subfamily A polypeptide 13 [EC:1.14.14.1]","XP_016802409.1//PREDICTED: cytochrome P450 2A7 [Pan troglodytes];XP_011807890.1//PREDICTED: cytochrome P450 2A13-like isoform X2 [Colobus angolensis palliatus]","2//1"]
[259236,1861,0.04,0.01,-2,0.629867204407713,"*",0.500968,"TMIE","GO:0016021//integral component of membrane","NA","GO:0042472//inner ear morphogenesis;GO:0007605//sensory perception of sound","NA","XP_009237377.1//PREDICTED: LOW QUALITY PROTEIN: transmembrane inner ear expressed protein [Pongo abelii]","2//1"]
[7166,1815,0.04,0.01,-2,0.628482119846069,"*",0.500968,"TPH1","NA","NA","NA","K00502//tryptophan 5-monooxygenase [EC:1.14.16.4]","XP_008969740.1//PREDICTED: tryptophan 5-hydroxylase 1 [Pan paniscus]","2//1"]
[10655,2503,0.04,0.01,-2,0.627103113549095,"*",0.500968,"DMRT2","GO:0005634//nucleus;GO:0016021//integral component of membrane","GO:0046872//metal ion binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0042803//protein homodimerization activity","GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:2000287//positive regulation of myotome development;GO:0014807//regulation of somitogenesis;GO:0048706//embryonic skeletal system development;GO:0006351//transcription, DNA-templated","K19489//doublesex- and mab-3-related transcription factor 2","NP_870987.2//doublesex- and mab-3-related transcription factor 2 isoform 2 [Homo sapiens];AAF86295.1//DMRT2/terra-like protein [Homo sapiens]","6;4;2//1"]
[122618,1998,0.04,0.01,-2,0.625290110329739,"*",0.500968,"PLD4","GO:0045335//phagocytic vesicle;GO:0032588//trans-Golgi network membrane;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0004630//phospholipase D activity;GO:0004435//phosphatidylinositol phospholipase C activity;GO:0003824//catalytic activity;GO:0070290//N-acylphosphatidylethanolamine-specific phospholipase D activity","GO:0002244//hematopoietic progenitor cell differentiation;GO:0016042//lipid catabolic process;GO:0043647//inositol phosphate metabolic process;GO:0006909//phagocytosis","K16860//phospholipase D3/4 [EC:3.1.4.4]","NP_001295103.1//phospholipase D4 isoform 1 [Homo sapiens];XP_003807044.1//PREDICTED: phospholipase D4 [Pan paniscus]","1//3;3//A2MP1"]
[284071,4688,2.36,0.62,-1.92844673897497,{"v":2.5223598e-14,"d":"2.52E-14"},"Down",{"v":1.856952E-15,"d":"1.86E-15"},"MEIOC","GO:0005634//nucleus;GO:0005737//cytoplasm","NA","GO:0048599//oocyte development;GO:0007141//male meiosis I;GO:0007286//spermatid development;GO:0007144//female meiosis I;GO:0007130//synaptonemal complex assembly;GO:0006302//double-strand break repair;GO:0070192//chromosome organization involved in meiotic cell cycle;GO:0051729//germline cell cycle switching, mitotic to meiotic cell cycle;GO:0051310//metaphase plate congression;GO:0048255//mRNA stabilization","NA","NP_001138552.2//meiosis-specific coiled-coil domain-containing protein MEIOC [Homo sapiens]","2//1"]
[347517,1077,0.3,0.08,-1.90689059560852,0.35797274433789,"*",0.21966,"RAB41","GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0000139//Golgi membrane","GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0042147//retrograde transport, endosome to Golgi;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0006891//intra-Golgi vesicle-mediated transport","K07896//Ras-related protein Rab-41","NP_001027898.2//ras-related protein Rab-41 [Homo sapiens]","2//1"]
[29841,3610,0.26,0.07,-1.89308479608349,0.0506537991735537,"*",0.0214868,"GRHL1","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0031490//chromatin DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0044212//transcription regulatory region DNA binding","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0045616//regulation of keratinocyte differentiation;GO:0008544//epidermis development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0061436//establishment of skin barrier;GO:0019216//regulation of lipid metabolic process;GO:0002934//desmosome organization","K09275//transcription factor CP2 and related proteins","NP_937825.2//grainyhead-like protein 1 homolog [Homo sapiens]","2//1"]
[1945,1257,7.37,2.04,-1.85309546712357,{"v":2.53817388407728e-11,"d":"2.54E-11"},"Down",{"v":2.385E-12,"d":"2.39E-12"},"EFNA4","GO:0005887//integral component of plasma membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0031225//anchored component of membrane","GO:0046875//ephrin receptor binding;GO:0005005//transmembrane-ephrin receptor activity","GO:0030316//osteoclast differentiation;GO:0048013//ephrin receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0046849//bone remodeling;GO:0007411//axon guidance","K05462//ephrin-A","XP_009180736.1//ephrin-A4 isoform X1 [Papio anubis];NP_872631.1//ephrin-A4 isoform b precursor [Homo sapiens];XP_017723265.1//PREDICTED: ephrin-A4 isoform X2 [Rhinopithecus bieti]","1//3;2//1"]
[196993,1842,0.61,0.17,-1.84327449631255,0.0463234554231975,"*",0.01942662,"CT62","NA","NA","NA","NA","NP_001096128.1//cancer/testis antigen 62 [Homo sapiens]","1//3"]
[554250,1773,0.42,0.12,-1.8073549220576,0.0852927814911438,"*",0.0388874,"GDF5OS","GO:0005615//extracellular space;GO:0005622//intracellular;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0008083//growth factor activity;GO:0005125//cytokine activity;GO:0042802//identical protein binding;GO:0005160//transforming growth factor beta receptor binding;GO:0036122//BMP binding","GO:0045666//positive regulation of neuron differentiation;GO:0040014//regulation of multicellular organism growth;GO:0035137//hindlimb morphogenesis;GO:0007184//SMAD protein import into nucleus;GO:0030513//positive regulation of BMP signaling pathway;GO:0032332//positive regulation of chondrocyte differentiation;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:2001054//negative regulation of mesenchymal cell apoptotic process;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0048468//cell development;GO:0009612//response to mechanical stimulus;GO:0007267//cell-cell signaling;GO:0043524//negative regulation of neuron apoptotic process;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0043408//regulation of MAPK cascade;GO:0030326//embryonic limb morphogenesis;GO:0060395//SMAD protein signal transduction;GO:0035136//forelimb morphogenesis;GO:0032331//negative regulation of chondrocyte differentiation;GO:0002062//chondrocyte differentiation;GO:0043932//ossification involved in bone remodeling;GO:0050680//negative regulation of epithelial cell proliferation;GO:0042981//regulation of apoptotic process;GO:0060591//chondroblast differentiation","K04664//growth differentiation factor 5","XP_018872428.1//PREDICTED: growth/differentiation factor 5 [Gorilla gorilla gorilla]","1//3"]
[51666,3824,1.02,0.3,-1.76553474636298,{"v":3.68437523837209e-05,"d":"3.68E-05"},"Down",{"v":7.9343e-06,"d":"7.93E-06"},"ASB4","GO:0005634//nucleus;GO:0031462//Cul2-RING ubiquitin ligase complex;GO:0000151//ubiquitin ligase complex;GO:0005829//cytosol;GO:0031466//Cul5-RING ubiquitin ligase complex;GO:0005737//cytoplasm","GO:0061630//ubiquitin protein ligase activity;GO:0031625//ubiquitin protein ligase binding;GO:0004842//ubiquitin-protein transferase activity","GO:0043687//post-translational protein modification;GO:2001214//positive regulation of vasculogenesis;GO:0016567//protein ubiquitination;GO:0051865//protein autoubiquitination;GO:0035556//intracellular signal transduction","K10326//ankyrin repeat and SOCS box protein 4","NP_665879.1//ankyrin repeat and SOCS box protein 4 isoform b [Homo sapiens];NP_057200.1//ankyrin repeat and SOCS box protein 4 isoform a [Homo sapiens]","2//1"]
[7539,2906,0.47,0.14,-1.74723392962003,0.0275959952359551,"*",0.01076268,"ZFP37","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_015986052.1//PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 37 homolog [Rousettus aegyptiacus]","1//3;2//1"]
[1562,2385,0.1,0.03,-1.73696559416621,0.530884318727915,"*",0.376212,"CYP2C18","GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0005789//endoplasmic reticulum membrane","GO:0008395//steroid hydroxylase activity;GO:0020037//heme binding;GO:0005506//iron ion binding;GO:0019825//oxygen binding;GO:0008392//arachidonic acid epoxygenase activity;GO:0034875//caffeine oxidase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0008144//drug binding;GO:0070330//aromatase activity;GO:0004497//monooxygenase activity","GO:0008202//steroid metabolic process;GO:0042738//exogenous drug catabolic process;GO:0019627//urea metabolic process;GO:0070989//oxidative demethylation;GO:0016098//monoterpenoid metabolic process;GO:0006805//xenobiotic metabolic process;GO:0019373//epoxygenase P450 pathway","K07413//cytochrome P450 family 2 subfamily C [EC:1.14.14.1];K17721//cytochrome P450 family 2 subfamily C polypeptide 19 [EC:1.14.14.51 1.14.14.52 1.14.14.53 1.14.14.-];K17720//cytochrome P450 family 2 subfamily C polypeptide 18 [EC:1.14.14.1];K17719//cytochrome P450 family 2 subfamily C polypeptide 9 [EC:1.14.14.51 1.14.14.52 1.14.14.53 1.14.14.-]","NP_001122397.1//cytochrome P450 2C18 isoform 2 precursor [Homo sapiens];XP_003783775.1//PREDICTED: cytochrome P450 2C19 [Otolemur garnettii]","1//3;2//1"]
[9848,6356,1.03,0.31,-1.73230421679634,{"v":1.93862471204189e-08,"d":"1.94E-08"},"Down",{"v":2.5498E-9,"d":"2.55E-09"},"MFAP3L","GO:0005634//nucleus;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm","NA","NA","K17341//hemicentin","XP_005263423.1//PREDICTED: microfi brillar-associated protein 3-like isoform X1 [Homo sapiens];XP_016864353.1//PREDICTED: microfi brillar-associated protein 3-like isoform X2 [Homo sapiens]","1//3;3//A2MP1;7"]
[912,3795,0.13,0.04,-1.70043971814109,0.141403583131022,"*",0.0707372,"CD1D","GO:0005765//lysosomal membrane;GO:0010008//endosome membrane;GO:0016323//basolateral plasma membrane;GO:0005783//endoplasmic reticulum;GO:0005737//cytoplasm;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane","GO:0042393//histone binding;GO:0030884//exogenous lipid antigen binding;GO:0050839//cell adhesion molecule binding;GO:0071723//lipopeptide binding;GO:0030883//endogenous lipid antigen binding;GO:0030881//beta-2-microglobulin binding;GO:0004872//receptor activity;GO:0030882//lipid antigen binding","GO:0045089//positive regulation of innate immune response;GO:0042102//positive regulation of T cell proliferation;GO:0016032//viral process;GO:0048007//antigen processing and presentation, exogenous lipid antigen via MHC class Ib;GO:0045058//T cell selection;GO:0016045//detection of bacterium;GO:0048006//antigen processing and presentation, endogenous lipid antigen via MHC class Ib;GO:0034113//heterotypic cell-cell adhesion;GO:0045087//innate immune response;GO:0050776//regulation of immune response","K06448//T-cell surface glycoprotein CD1","NP_001757.1//antigen-presenting glycoprotein CD1d isoform 1 precursor [Homo sapiens];NP_001306074.1//antigen-presenting glycoprotein CD1d isoform 2 precursor [Homo sapiens]","1//3;3//A2MP1"]
[53826,1804,0.13,0.04,-1.70043971814109,0.530368942546995,"*",0.376212,"FXYD6","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005216//ion channel activity;GO:0017080//sodium channel regulator activity","GO:1903779//regulation of cardiac conduction;GO:2000649//regulation of sodium ion transmembrane transporter activity;GO:0034220//ion transmembrane transport","K13363//FXYD domain-containing ion transport regulator 6","XP_011782242.1//PREDICTED: FXYD domain-containing ion transport regulator 6 isoform X2 [Colobus angolensis palliatus];XP_012351380.1//PREDICTED: FXYD domain-containing ion transport regulator 6 isoform X1 [Nomascus leucogenys];XP_014202520.1//PREDICTED: FXYD domain-containing ion transport regulator 6 isoform X1 [Pan paniscus]","3//A2MP1;2//1"]
[2567,1512,0.16,0.05,-1.67807190511264,0.531259767326733,"*",0.376212,"GABRG3","GO:0030054//cell junction;GO:0034707//chloride channel complex;GO:0005886//plasma membrane;GO:0045211//postsynaptic membrane","GO:0005230//extracellular ligand-gated ion channel activity;GO:0004890//GABA-A receptor activity;GO:0005254//chloride channel activity","GO:0042493//response to drug;GO:0034220//ion transmembrane transport;GO:0007214//gamma-aminobutyric acid signaling pathway","K05186//gamma-aminobutyric acid receptor subunit gamma","XP_008015527.1//PREDICTED: gamma-aminobutyric acid receptor subunit gamma-3 [Chlorocebus sabaeus]","1//3;4"]
[149420,4270,1.13,0.36,-1.65025396097288,{"v":9.57519657420609e-06,"d":"9.58E-06"},"Down",{"v":1.849822E-6,"d":"1.85E-06"},"PDIK1L","NA","GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding","NA","K17539//serine/threonine-protein kinase PDIK1L [EC:2.7.11.1]","EDL30020.1//PDLIM1 interacting kinase 1 like, isoform CRA_b, partial [Mus musculus];XP_004425820.2//PREDICTED: serine/threonine-protein kinase PDIK1L isoform X1 [Ceratotherium simum simum];XP_012295636.1//serine/threonine-protein kinase PDIK1L isoform X1 [Aotus nancymaae]","1//3;4"]
[23643,642,0.4,0.13,-1.62148837674627,0.529948014814815,"*",0.376212,"LY96","GO:0010008//endosome membrane;GO:0031226//intrinsic component of plasma membrane;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0046696//lipopolysaccharide receptor complex","GO:0015026//coreceptor activity;GO:0001875//lipopolysaccharide receptor activity","GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0097190//apoptotic signaling pathway;GO:0032496//response to lipopolysaccharide;GO:0007166//cell surface receptor signaling pathway;GO:0031666//positive regulation of lipopolysaccharide-mediated signaling pathway;GO:0032760//positive regulation of tumor necrosis factor production;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0045087//innate immune response;GO:0034142//toll-like receptor 4 signaling pathway;GO:0032497//detection of lipopolysaccharide;GO:0006968//cellular defense response;GO:0002224//toll-like receptor signaling pathway;GO:0006954//inflammatory response;GO:0034128//negative regulation of MyD88-independent toll-like receptor signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0070266//necroptotic process;GO:0002755//MyD88-dependent toll-like receptor signaling pathway","K05400//lymphocyte antigen 96","NP_001182726.1//lymphocyte antigen 96 isoform 2 precursor [Homo sapiens];NP_001123946.1//lymphocyte antigen 96 precursor [Pan troglodytes]","1//3;4"]
[80823,4000,0.73,0.24,-1.60486205815886,0.000827990507272727,"Down",2.28068E-4,"BHLHB9","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005829//cytosol","GO:0042803//protein homodimerization activity","GO:0050769//positive regulation of neurogenesis;GO:0043524//negative regulation of neuron apoptotic process;GO:0051965//positive regulation of synapse assembly;GO:0061003//positive regulation of dendritic spine morphogenesis;GO:0007611//learning or memory","NA","NP_085142.1//protein BHLHb9 [Homo sapiens]","1//3;2//1"]
[8863,6309,1.35,0.45,-1.58496250072116,{"v":8.47373717647059e-09,"d":"8.47E-09"},"Down",{"v":1.064124e-09,"d":"1.06E-09"},"PER3","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0031625//ubiquitin protein ligase binding;GO:0019900//kinase binding","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0032922//circadian regulation of gene expression;GO:0050821//protein stabilization;GO:0045187//regulation of circadian sleep/wake cycle, sleep","K21945//period circadian protein 3","NP_001276790.1//period circadian protein homolog 3 isoform 2 [Homo sapiens];NP_001276791.1//period circadian protein homolog 3 isoform 1 [Homo sapiens];NP_001276792.1//period circadian protein homolog 3 isoform 3 [Homo sapiens];XP_016858224.1//PREDICTED: period circadian protein homolog 3 isoform X15 [Homo sapiens];NP_058515.1//period circadian protein homolog 3 isoform 4 [Homo sapiens]","1//3;2//1"]
[257240,3039,0.03,0.01,-1.58496250072116,0.640145814894808,"*",0.500968,"KLHL34","GO:0005615//extracellular space;GO:0031463//Cul3-RING ubiquitin ligase complex","NA","GO:0016567//protein ubiquitination","K10469//kelch-like protein 34","NP_695002.1//kelch-like protein 34 [Homo sapiens]","2//1"]
[7730,2381,0.21,0.07,-1.58496250072116,0.306520596175908,"*",0.1806426,"ZNF177","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_004378617.1//PREDICTED: zinc finger protein 560 [Trichechus manatus latirostris];XP_017171168.1//PREDICTED: zinc finger protein 431-like isoform X1 [Mus musculus]","1//3;2//1"]
[29906,2627,0.03,0.01,-1.58496250072116,0.637646440796813,"*",0.500968,"ST8SIA5","GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0008373//sialyltransferase activity;GO:0003828//alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity","GO:0006486//protein glycosylation;GO:0006688//glycosphingolipid biosynthetic process;GO:0005975//carbohydrate metabolic process","K03369//alpha-N-acetyl-neuraminate alpha-2,8-sialyltransferase (sialyltransferase 8E) [EC:2.4.99.-]","NP_001294916.1//alpha-2,8-sialyltransferase 8E isoform 3 [Homo sapiens];NP_037437.2//alpha-2,8-sialyltransferase 8E isoform 2 [Homo sapiens];NP_001294915.1//alpha-2,8-sialyltransferase 8E isoform 1 [Homo sapiens]","1//3;5"]
[401498,5399,0.03,0.01,-1.58496250072116,0.733165520990549,"*",0.626454,"TMEM215","GO:0016021//integral component of membrane","NA","NA","NA","NP_997723.2//transmembrane protein 215 [Homo sapiens]","2//1"]
[6975,2810,0.03,0.01,-1.58496250072116,0.636125821303657,"*",0.500968,"TECTB","GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0031225//anchored component of membrane;GO:0005578//proteinaceous extracellular matrix","GO:0005201//extracellular matrix structural constituent","GO:0006501//C-terminal protein lipidation","K18274//uromodulin;K19899//pancreatic secretory granule membrane major glycoprotein GP2;K18273//alpha-tectorin","NP_478129.1//beta-tectorin precursor [Homo sapiens]","2//1"]
[55289,2373,0.03,0.01,-1.58496250072116,0.634562114978987,"*",0.500968,"ACOXL","NA","NA","NA","K00232//acyl-CoA oxidase [EC:1.3.3.6]","XP_018876900.1//PREDICTED: acyl-coenzyme A oxidase-like protein [Gorilla gorilla gorilla]","1//3"]
[64446,2292,0.03,0.01,-1.58496250072116,0.632655769784173,"*",0.500968,"DNAI2","GO:0036126//sperm flagellum;GO:0036157//outer dynein arm;GO:0005874//microtubule;GO:0009897//external side of plasma membrane;GO:0005737//cytoplasm;GO:0005930//axoneme;GO:0005858//axonemal dynein complex","GO:0003777//microtubule motor activity;GO:0045503//dynein light chain binding;GO:0045504//dynein heavy chain binding","GO:0003341//cilium movement;GO:0060271//cilium assembly;GO:0007368//determination of left/right symmetry;GO:0036158//outer dynein arm assembly","K11143//dynein intermediate chain 2, axonemal","NP_001166281.1//dynein intermediate chain 2, axonemal isoform 2 [Homo sapiens];NP_001340096.1//dynein intermediate chain 2, axonemal isoform 3 [Homo sapiens];EAW89148.1//dynein, axonemal, intermediate polypeptide 2, isoform CRA_e [Homo sapiens]","1//3;2//1;5"]
[151531,2410,0.03,0.01,-1.58496250072116,0.631557322389709,"*",0.500968,"UPP2","GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0045098//type III intermediate filament","GO:0004850//uridine phosphorylase activity","GO:0046135//pyrimidine nucleoside catabolic process;GO:0009116//nucleoside metabolic process;GO:0043097//pyrimidine nucleoside salvage;GO:0046108//uridine metabolic process;GO:0044206//UMP salvage;GO:0009166//nucleotide catabolic process","K00757//uridine phosphorylase [EC:2.4.2.3]","NP_001128570.1//uridine phosphorylase 2 isoform b [Homo sapiens]","1//3;3//A2MP1"]
[56100,4599,0.03,0.01,-1.58496250072116,0.391237386343655,"*",0.250726,"PCDHGB6","NA","NA","NA","K16496//protocadherin gamma subfamily B;K16495//protocadherin gamma subfamily A","XP_012501267.1//PREDICTED: protocadherin gamma-B6 isoform X9 [Propithecus coquereli];XP_015340968.1//PREDICTED: protocadherin gamma-B6 [Marmota marmota marmota]","1//3;2//1"]
[158248,2860,0.03,0.01,-1.58496250072116,0.628827819581958,"*",0.500968,"TTC16","NA","NA","NA","K22020//mucin-19","NP_659402.1//tetratricopeptide repeat protein 16 isoform 1 [Homo sapiens];NP_001303966.1//tetratricopeptide repeat protein 16 isoform 2 [Homo sapiens]","1//3;2//1"]
[1755,7656,0.03,0.01,-1.58496250072116,0.226906746117274,"*",0.1254848,"DMBT1","GO:0042589//zymogen granule membrane;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0019898//extrinsic component of membrane;GO:0005576//extracellular region;GO:0030670//phagocytic vesicle membrane;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0035375//zymogen binding;GO:1904399//heparan sulfate binding;GO:0001530//lipopolysaccharide binding;GO:0005044//scavenger receptor activity;GO:0038187//pattern recognition receptor activity;GO:0048306//calcium-dependent protein binding;GO:0070891//lipoteichoic acid binding;GO:0008329//signaling pattern recognition receptor activity","GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0050829//defense response to Gram-negative bacterium;GO:0051607//defense response to virus;GO:0016032//viral process;GO:0044267//cellular protein metabolic process;GO:0006898//receptor-mediated endocytosis;GO:0007275//multicellular organism development;GO:0050830//defense response to Gram-positive bacterium;GO:0043152//induction of bacterial agglutination;GO:0045087//innate immune response;GO:0015031//protein transport;GO:0030855//epithelial cell differentiation","K13912//deleted in malignant brain tumors 1 protein","NP_060049.2//deleted in malignant brain tumors 1 protein isoform c precursor [Homo sapiens];NP_015568.2//deleted in malignant brain tumors 1 protein isoform b precursor [Homo sapiens];NP_004397.2//deleted in malignant brain tumors 1 protein isoform a precursor [Homo sapiens];NP_001307573.1//deleted in malignant brain tumors 1 protein isoform d precursor [Homo sapiens]","1//3;2//1"]
[54514,2379,0.03,0.01,-1.58496250072116,0.62602384667136,"*",0.500968,"DDX4","GO:0005730//nucleolus;GO:0071547//piP-body;GO:0071546//pi-body;GO:0043186//P granule;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm","GO:0004004//ATP-dependent RNA helicase activity;GO:0005524//ATP binding;GO:0004386//helicase activity;GO:0003676//nucleic acid binding;GO:0016887//ATPase activity","GO:0030317//flagellated sperm motility;GO:1990511//piRNA biosynthetic process;GO:0007141//male meiosis I;GO:0030154//cell differentiation;GO:0031047//gene silencing by RNA;GO:0007283//spermatogenesis;GO:0034587//piRNA metabolic process;GO:0007140//male meiotic nuclear division;GO:0010529//negative regulation of transposition;GO:0043046//DNA methylation involved in gamete generation;GO:0007275//multicellular organism development;GO:0010501//RNA secondary structure unwinding","K13982//probable ATP-dependent RNA helicase DDX4 [EC:3.6.4.13]","NP_001160006.1//probable ATP-dependent RNA helicase DDX4 isoform 4 [Homo sapiens];NP_077726.1//probable ATP-dependent RNA helicase DDX4 isoform 1 [Homo sapiens];NP_001136021.1//probable ATP-dependent RNA helicase DDX4 isoform 2 [Homo sapiens];NP_001160005.1//probable ATP-dependent RNA helicase DDX4 isoform 3 [Homo sapiens]","1//3;2//1"]
[110599588,671,2.35,0.8,-1.55458885167764,0.0365206129139686,"*",0.01482864,"ASDURF","NA","GO:0042803//protein homodimerization activity;GO:0004066//asparagine synthase (glutamine-hydrolyzing) activity","GO:0006541//glutamine metabolic process;GO:0006529//asparagine biosynthetic process","NA","XP_004484986.2//PREDICTED: asparagine synthetase domain-containing protein 1 [Dasypus novemcinctus]","1//3"]
[58480,4386,1.99,0.69,-1.52810016376548,{"v":1.43858359324324E-8,"d":"1.44E-08"},"Down",{"v":1.865998e-09,"d":"1.87E-09"},"RHOU","GO:0016020//membrane;GO:0042995//cell projection;GO:0005925//focal adhesion;GO:0002102//podosome;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005886//plasma membrane;GO:0000139//Golgi membrane","GO:0046872//metal ion binding;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0030036//actin cytoskeleton organization;GO:1903955//positive regulation of protein targeting to mitochondrion;GO:0008360//regulation of cell shape;GO:0016601//Rac protein signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0007010//cytoskeleton organization;GO:0000082//G1/S transition of mitotic cell cycle;GO:0051056//regulation of small GTPase mediated signal transduction","K07865//Ras homolog gene family, member U","BAD92748.1//ras homolog gene family, member U variant, partial [Homo sapiens]",5]
[284194,1243,0.2,0.07,-1.51457317282976,0.732736047155305,"*",0.626454,"LGALS9B","GO:0005829//cytosol","GO:0030246//carbohydrate binding","NA","K10093//galectin-9","NP_001036150.1//galectin-9B [Homo sapiens]","1//3"]
[25822,2465,4.12,1.46,-1.4966759683032,{"v":1.30483781462342e-09,"d":"1.30E-09"},"Down",{"v":1.485852E-10,"d":"1.49E-10"},"DNAJB5","GO:0005634//nucleus;GO:0005829//cytosol","GO:0051082//unfolded protein binding;GO:0051087//chaperone binding","GO:0006457//protein folding;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006986//response to unfolded protein","K09511//DnaJ homolog subfamily B member 5","XP_017721088.1//PREDICTED: dnaJ homolog subfamily B member 5 isoform X1 [Rhinopithecus bieti];NP_001128477.1//dnaJ homolog subfamily B member 5 isoform 1 [Homo sapiens];EFB22142.1//hypothetical protein PANDA_021017, partial [Ailuropoda melanoleuca];NP_001128476.2//dnaJ homolog subfamily B member 5 isoform 2 [Homo sapiens];NP_001336654.1//dnaJ homolog subfamily B member 5 isoform 4 [Homo sapiens]","1//3;2//1;5"]
[8911,9902,0.11,0.04,-1.4594316186373,0.0906561893336952,"*",0.0418208,"CACNA1I","GO:0005886//plasma membrane;GO:0005891//voltage-gated calcium channel complex","GO:0008332//low voltage-gated calcium channel activity;GO:0005245//voltage-gated calcium channel activity;GO:0005248//voltage-gated sodium channel activity","GO:0006810//transport;GO:0030317//flagellated sperm motility;GO:0007165//signal transduction;GO:0019228//neuronal action potential;GO:0086010//membrane depolarization during action potential;GO:0070509//calcium ion import;GO:0030431//sleep;GO:0045956//positive regulation of calcium ion-dependent exocytosis","K04856//voltage-dependent calcium channel T type alpha-1I","NP_001003406.1//voltage-dependent T-type calcium channel subunit alpha-1I isoform b [Homo sapiens];NP_066919.2//voltage-dependent T-type calcium channel subunit alpha-1I isoform a [Homo sapiens]","1//3;3//A2MP1"]
[56137,5404,0.63,0.23,-1.4537179674429,1.11777631212591E-3,"*",0.000315656,"PCDHA12","NA","NA","NA","K16493//protocadherin alpha","XP_003266535.1//PREDICTED: protocadherin alpha-12 isoform X2 [Nomascus leucogenys]","3//A2MP1;2//1"]
[4851,9322,4.03,1.48,-1.44518266289902,{"v":1.07732884411765E-31,"d":"1.08E-31"},"Down",{"v":2.75166e-33,"d":"2.75E-33"},"NOTCH1","GO:0009986//cell surface;GO:0016324//apical plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0001669//acrosomal vesicle;GO:0005912//adherens junction","GO:0005509//calcium ion binding;GO:0031490//chromatin DNA binding;GO:0019899//enzyme binding;GO:0001047//core promoter binding","GO:0031100//animal organ regeneration;GO:0003180//aortic valve morphogenesis;GO:1902263//apoptotic process involved in embryonic digit morphogenesis;GO:0060842//arterial endothelial cell differentiation;GO:0003162//atrioventricular node development","K02599//Notch 1","NP_060087.3//neurogenic locus notch homolog protein 1 preproprotein [Homo sapiens]",4]
[644943,2698,3.87,1.45,-1.41628066612948,{"v":4.87949823868313e-09,"d":"4.88E-09"},"Down",{"v":5.93824e-10,"d":"5.94E-10"},"RASSF10","NA","NA","NA","K09856//Ras association domain-containing protein 9/10","XP_003910253.2//ras association domain-containing protein 10 [Papio anubis]","2//1"]
[200373,2854,0.08,0.03,-1.41503749927884,0.531871005221701,"*",0.376212,"CFAP221","GO:0005929//cilium;GO:0005737//cytoplasm;GO:0005930//axoneme","GO:0005516//calmodulin binding","GO:0003341//cilium movement;GO:0060271//cilium assembly;GO:0044458//motile cilium assembly","K17570//hydrocephalus-inducing protein","NP_001257978.1//cilia- and flagella-associated protein 221 [Homo sapiens]","1//3"]
[253017,2843,0.08,0.03,-1.41503749927884,0.730329601226098,"*",0.626454,"TECRL","GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane","GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors;GO:0016491//oxidoreductase activity","GO:0042761//very long-chain fatty acid biosynthetic process","K10258//very-long-chain enoyl-CoA reductase [EC:1.3.1.93]","EAX05533.1//hCG2038358, partial [Homo sapiens]",4]
[100288413,2889,0.58,0.22,-1.39854937649027,0.027763867370109,"*",0.01083858,"ERVMER34-1","GO:0019031//viral envelope;GO:0016021//integral component of membrane","NA","NA","NA","NP_078810.1//endogenous retrovirus group MER34 member 1 Env polyprotein precursor [Homo sapiens]","1//3;5"]
[83538,3099,1.08,0.41,-1.39733549754539,0.00202086919174041,"*",0.000600416,"TTC25","GO:0005856//cytoskeleton;GO:0042995//cell projection;GO:0005737//cytoplasm","NA","NA","K15837//G-protein signaling modulator 2;K02145//V-type H+-transporting ATPase subunit A [EC:3.6.3.14];K09553//stress-induced-phosphoprotein 1","NP_001337248.1//tetratricopeptide repeat protein 25 isoform 2 [Homo sapiens];NP_113609.1//tetratricopeptide repeat protein 25 isoform 1 [Homo sapiens]","1//3;4"]
[5028,6802,0.13,0.05,-1.37851162325373,0.152252052368648,"*",0.0774604,"P2RY1","GO:0030425//dendrite;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0014069//postsynaptic density;GO:0044297//cell body;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0045211//postsynaptic membrane","GO:0045028//G-protein coupled purinergic nucleotide receptor activity;GO:0005524//ATP binding;GO:0004872//receptor activity;GO:0046982//protein heterodimerization activity;GO:0045032//ADP-activated adenosine receptor activity;GO:0031686//A1 adenosine receptor binding;GO:0097110//scaffold protein binding;GO:0043531//ADP binding;GO:0045031//ATP-activated adenosine receptor activity","GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0030168//platelet activation;GO:0007166//cell surface receptor signaling pathway;GO:0023019//signal transduction involved in regulation of gene expression;GO:0010700//negative regulation of norepinephrine secretion;GO:0071407//cellular response to organic cyclic compound;GO:0008347//glial cell migration;GO:0019233//sensory perception of pain;GO:0001934//positive regulation of protein phosphorylation;GO:0010469//regulation of receptor activity;GO:0060406//positive regulation of penile erection;GO:0090075//relaxation of muscle;GO:0097746//regulation of blood vessel diameter;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway;GO:0009612//response to mechanical stimulus;GO:0043270//positive regulation of ion transport;GO:0072659//protein localization to plasma membrane;GO:0042755//eating behavior;GO:0051100//negative regulation of binding;GO:0007568//aging;GO:0046887//positive regulation of hormone secretion;GO:0070848//response to growth factor;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0032962//positive regulation of inositol trisphosphate biosynthetic process;GO:0070374//positive regulation of ERK1 and ERK2 cascade","K04270//purinergic receptor P2Y, G protein-coupled, 1","NP_002554.1//P2Y purinoceptor 1 [Homo sapiens]",4]
[7026,4695,10.94,4.26,-1.36068740256672,{"v":3.148667088e-47,"d":"3.15E-47"},"Down",{"v":4.9278e-49,"d":"4.93E-49"},"NR2F2","GO:0005634//nucleus","GO:0003707//steroid hormone receptor activity;GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0042803//protein homodimerization activity;GO:0004879//nuclear receptor activity;GO:0043565//sequence-specific DNA binding;GO:0008270//zinc ion binding;GO:0001972//retinoic acid binding;GO:0003700//DNA binding transcription factor activity","GO:0009952//anterior/posterior pattern specification;GO:0045893//positive regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0032355//response to estradiol;GO:0060674//placenta blood vessel development;GO:0001893//maternal placenta development;GO:0001937//negative regulation of endothelial cell proliferation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0007165//signal transduction;GO:0009566//fertilization;GO:0001945//lymph vessel development;GO:0010596//negative regulation of endothelial cell migration;GO:0006351//transcription, DNA-templated;GO:0009956//radial pattern formation;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0060707//trophoblast giant cell differentiation;GO:0003084//positive regulation of systemic arterial blood pressure;GO:0060173//limb development;GO:0030900//forebrain development;GO:0001764//neuron migration;GO:0048514//blood vessel morphogenesis;GO:0007519//skeletal muscle tissue development;GO:0060849//regulation of transcription involved in lymphatic endothelial cell fate commitment;GO:0006629//lipid metabolic process","K08548//COUP transcription factor 2","XP_004468158.1//PREDICTED: LOW QUALITY PROTEIN: COUP transcription factor 2 [Dasypus novemcinctus];XP_004271711.1//PREDICTED: COUP transcription factor 2 isoform X3 [Orcinus orca];NP_899084.2//COUP transcription factor 2 isoform 2 [Mus musculus];XP_015273866.1//PREDICTED: COUP transcription factor 2 isoform X1 [Gekko japonicus]","1//3;3//A2MP1"]
[79819,1965,0.23,0.09,-1.3536369546147,0.631624178108758,"*",0.50972,"WDR78","GO:0005858//axonemal dynein complex","GO:0045503//dynein light chain binding;GO:0045504//dynein heavy chain binding","GO:0003341//cilium movement;GO:0002244//hematopoietic progenitor cell differentiation","K22001//insulin-like 5;K10409//dynein intermediate chain 1, axonemal","NP_079039.4//WD repeat-containing protein 78 isoform 1 [Homo sapiens];NP_996897.2//WD repeat-containing protein 78 isoform 2 [Homo sapiens]","4;2//1"]
[4297,16599,2.54,1.01,-1.33047320402037,{"v":2.1593444338983e-31,"d":"2.16E-31"},"Down",{"v":5.58288e-33,"d":"5.58E-33"},"KMT2A","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0071339//MLL1 complex;GO:0035097//histone methyltransferase complex;GO:0005829//cytosol","GO:0001046//core promoter sequence-specific DNA binding;GO:0042802//identical protein binding;GO:0042800//histone methyltransferase activity (H3-K4 specific);GO:0003680//AT DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0042803//protein homodimerization activity;GO:0070577//lysine-acetylated histone binding;GO:0045322//unmethylated CpG binding;GO:0003682//chromatin binding;GO:0008270//zinc ion binding;GO:0003700//DNA binding transcription factor activity;GO:0018024//histone-lysine N-methyltransferase activity","GO:2001040//positive regulation of cellular response to drug;GO:0032411//positive regulation of transporter activity;GO:0009791//post-embryonic development;GO:0048172//regulation of short-term neuronal synaptic plasticity;GO:0008285//negative regulation of cell proliferation;GO:0044648//histone H3-K4 dimethylation;GO:0006915//apoptotic process;GO:0035864//response to potassium ion;GO:0018026//peptidyl-lysine monomethylation;GO:0071440//regulation of histone H3-K14 acetylation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:1902036//regulation of hematopoietic stem cell differentiation;GO:0006461//protein complex assembly;GO:0009952//anterior/posterior pattern specification;GO:0008542//visual learning;GO:0051568//histone H3-K4 methylation;GO:0048873//homeostasis of number of cells within a tissue;GO:0045893//positive regulation of transcription, DNA-templated;GO:0035162//embryonic hemopoiesis;GO:0060216//definitive hemopoiesis;GO:1901674//regulation of histone H3-K27 acetylation;GO:0048536//spleen development;GO:0032922//circadian regulation of gene expression;GO:0051571//positive regulation of histone H3-K4 methylation;GO:0043984//histone H4-K16 acetylation;GO:0006351//transcription, DNA-templated;GO:0006306//DNA methylation;GO:0045652//regulation of megakaryocyte differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0035640//exploration behavior;GO:0051899//membrane depolarization;GO:0080182//histone H3-K4 trimethylation;GO:2000615//regulation of histone H3-K9 acetylation","K09186//histone-lysine N-methyltransferase MLL1 [EC:2.1.1.43]","NP_005924.2//histone-lysine N-methyltransferase 2A isoform 2 precursor [Homo sapiens];NP_001184033.1//histone-lysine N-methyltransferase 2A isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[1995,4661,0.05,0.02,-1.32192809488736,0.531165855400389,"*",0.376212,"ELAVL3","NA","GO:0003723//RNA binding;GO:0017091//AU-rich element binding","GO:0007399//nervous system development;GO:0030154//cell differentiation","K13208//ELAV like protein 2/3/4","XP_017450979.1//PREDICTED: ELAV-like protein 3 isoform X1 [Rattus norvegicus];XP_006242678.2//PREDICTED: ELAV-like protein 3 isoform X2 [Rattus norvegicus]","3//A2MP1;2//1"]
[219736,1037,0.75,0.3,-1.32192809488736,0.012955992,"*",0.00462714,"STOX1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005938//cell cortex;GO:0005829//cytosol;GO:0001650//fibrillar center;GO:0005813//centrosome;GO:0005737//cytoplasm","GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding","GO:0010468//regulation of gene expression;GO:0051897//positive regulation of protein kinase B signaling;GO:1904031//positive regulation of cyclin-dependent protein kinase activity;GO:0010629//negative regulation of gene expression;GO:0071500//cellular response to nitrosative stress;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0048839//inner ear development;GO:0010821//regulation of mitochondrion organization;GO:1904120//positive regulation of otic vesicle morphogenesis;GO:0006351//transcription, DNA-templated;GO:0010628//positive regulation of gene expression;GO:1901858//regulation of mitochondrial DNA metabolic process;GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:1902882//regulation of response to oxidative stress;GO:0051301//cell division;GO:0010971//positive regulation of G2/M transition of mitotic cell cycle;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0051881//regulation of mitochondrial membrane potential;GO:0007049//cell cycle;GO:0050679//positive regulation of epithelial cell proliferation;GO:0008284//positive regulation of cell proliferation","K04632//guanine nucleotide-binding protein G(s) subunit alpha;K09228//KRAB domain-containing zinc finger protein","NP_001123631.1//storkhead-box protein 1 isoform b [Homo sapiens];XP_019479904.1//PREDICTED: storkhead-box protein 1 isoform X3 [Hipposideros armiger];NP_689922.3//storkhead-box protein 1 isoform a [Homo sapiens]","4;2//1"]
[255394,2055,0.45,0.18,-1.32192809488736,0.184434724881066,"*",0.0970782,"TCP11L2","NA","NA","NA","K13999//cytoskeleton-associated protein 4","NP_001273191.1//T-complex protein 11-like protein 2 isoform 2 [Homo sapiens];NP_689985.1//T-complex protein 11-like protein 2 isoform 1 [Homo sapiens]","1//3;2//1"]
[8341,449,0.92,0.37,-1.31410859042806,0.357389370543899,"*",0.21966,"HIST1H2BN","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0000786//nucleosome","GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity","GO:0016567//protein ubiquitination;GO:0006334//nucleosome assembly","K11252//histone H2B","XP_003502246.1//PREDICTED: histone H2B type 1 isoform X1 [Cricetulus griseus]","3//A2MP1"]
[3172,4707,10.34,4.18,-1.30666133823405,{"v":5.07263337127937e-33,"d":"5.07E-33"},"Down",{"v":1.216238e-34,"d":"1.22E-34"},"HNF4A","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm","GO:0003707//steroid hormone receptor activity;GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0005102//receptor binding;GO:0044212//transcription regulatory region DNA binding;GO:0003705//transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding;GO:0042803//protein homodimerization activity;GO:0004879//nuclear receptor activity;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0008270//zinc ion binding;GO:0005504//fatty acid binding;GO:0003700//DNA binding transcription factor activity;GO:0001102//RNA polymerase II activating transcription factor binding","GO:0007596//blood coagulation;GO:0060398//regulation of growth hormone receptor signaling pathway;GO:0023019//signal transduction involved in regulation of gene expression;GO:0050796//regulation of insulin secretion;GO:0045893//positive regulation of transcription, DNA-templated;GO:0042593//glucose homeostasis;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0070328//triglyceride homeostasis;GO:0009749//response to glucose;GO:0019216//regulation of lipid metabolic process;GO:2000189//positive regulation of cholesterol homeostasis;GO:0006591//ornithine metabolic process;GO:0008285//negative regulation of cell proliferation;GO:0030308//negative regulation of cell growth;GO:0055091//phospholipid homeostasis;GO:0006805//xenobiotic metabolic process;GO:0010470//regulation of gastrulation;GO:0006351//transcription, DNA-templated;GO:0060395//SMAD protein signal transduction;GO:0007548//sex differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0055088//lipid homeostasis;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006629//lipid metabolic process","K07292//hepatocyte nuclear factor 4-alpha","NP_001025175.1//hepatocyte nuclear factor 4-alpha isoform 6 [Homo sapiens];NP_849181.1//hepatocyte nuclear factor 4-alpha isoform 3 [Homo sapiens];NP_001274113.1//hepatocyte nuclear factor 4-alpha isoform 10 [Homo sapiens];XP_008578997.1//PREDICTED: hepatocyte nuclear factor 4-alpha isoform X3 [Galeopterus variegatus];NP_000448.3//hepatocyte nuclear factor 4-alpha 2 [Homo sapiens];AAB48082.1//hepatocyte nuclear factor 4-alpha [Homo sapiens];NP_849180.1//hepatocyte nuclear factor 4-alpha isoform 1 [Homo sapiens];NP_001025174.1//hepatocyte nuclear factor 4-alpha isoform 4 [Homo sapiens];XP_008578995.1//PREDICTED: hepatocyte nuclear factor 4-alpha isoform X1 [Galeopterus variegatus];NP_787110.2//hepatocyte nuclear factor 4-alpha isoform 5 [Homo sapiens]","4;1//3;2//1"]
[6239,8076,3.96,1.61,-1.29843974196499,{"v":1.36005998947368e-23,"d":"1.36E-23"},"Down",{"v":5.17664E-25,"d":"5.18E-25"},"RREB1","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0016604//nuclear body;GO:0016607//nuclear speck;GO:0001650//fibrillar center;GO:0005737//cytoplasm","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0003676//nucleic acid binding;GO:0046872//metal ion binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0007165//signal transduction;GO:0006355//regulation of transcription, DNA-templated;GO:2000394//positive regulation of lamellipodium morphogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0033601//positive regulation of mammary gland epithelial cell proliferation;GO:0010634//positive regulation of epithelial cell migration;GO:0007275//multicellular organism development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:1903691//positive regulation of wound healing, spreading of epidermal cells;GO:0007265//Ras protein signal transduction","K20210//ras-responsive element-binding protein 1","NP_001003700.1//ras-responsive element-binding protein 1 isoform 3 [Homo sapiens];NP_001003698.1//ras-responsive element-binding protein 1 isoform 2 [Homo sapiens];NP_001003699.1//ras-responsive element-binding protein 1 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[126364,2430,1.39,0.57,-1.28605105855877,3.49955346896276E-3,"*",1.094076E-3,"LRRC25","GO:0016021//integral component of membrane","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K11447//histone demethylase [EC:1.14.11.-];K01064//wingless-type MMTV integration site family, member 9","NP_660299.2//leucine-rich repeat-containing protein 25 precursor [Homo sapiens]","2//1"]
[153478,12628,0.17,0.07,-1.28010791919274,0.0144204305894627,"*",0.00519168,"PLEKHG4B","NA","NA","NA","K08810//triple functional domain protein [EC:2.7.11.1];K18655//ATP-dependent RNA helicase DDX19/DBP5 [EC:3.6.4.13]","NP_443141.4//pleckstrin homology domain-containing family G member 4B [Homo sapiens]",4]
[55252,12894,4.01,1.66,-1.272418995108,{"v":1.0922956E-35,"d":"1.09E-35"},"Down",{"v":2.34542e-37,"d":"2.35E-37"},"ASXL2","NA","NA","NA","K11471//additional sex combs-like protein","XP_005576426.1//PREDICTED: putative Polycomb group protein ASXL2 isoform X3 [Macaca fascicularis]",5]
[84162,15592,0.84,0.35,-1.26303440583379,{"v":2.38198225373134e-09,"d":"2.38E-09"},"Down",{"v":2.79742e-10,"d":"2.80E-10"},"KIAA1109","GO:0016020//membrane;GO:0005634//nucleus;GO:0016021//integral component of membrane","NA","GO:0001558//regulation of cell growth;GO:0030856//regulation of epithelial cell differentiation","K05741//diaphanous 2","NP_056127.2//uncharacterized protein KIAA1109 [Homo sapiens]","3//A2MP1"]
[27244,3019,2.9,1.21,-1.26104585274034,{"v":1.31400523636364e-06,"d":"1.31E-06"},"Down",{"v":2.21688e-07,"d":"2.22E-07"},"SESN1","GO:0005634//nucleus;GO:0005829//cytosol;GO:0061700//GATOR2 complex;GO:0001650//fibrillar center;GO:0005737//cytoplasm","GO:0070728//leucine binding;GO:0051920//peroxiredoxin activity","GO:0034198//cellular response to amino acid starvation;GO:0098869//cellular oxidant detoxification;GO:1901031//regulation of response to reactive oxygen species;GO:0072593//reactive oxygen species metabolic process;GO:0042149//cellular response to glucose starvation;GO:1904262//negative regulation of TORC1 signaling","K10141//sestrin 1/3","NP_055269.1//sestrin-1 isoform 1 [Homo sapiens];NP_001186862.1//sestrin-1 isoform 2 [Homo sapiens]","1//3;2//1"]
[56125,3271,0.19,0.08,-1.24792751344359,0.367326217422025,"*",0.227814,"PCDHB11","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005509//calcium ion binding","GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules","K16494//protocadherin beta","XP_003846023.1//PREDICTED: LOW QUALITY PROTEIN: protocadherin beta-11 [Pan paniscus]","2//1"]
[9658,8626,1.42,0.6,-1.24285652389616,{"v":1.18634299542133E-8,"d":"1.19E-08"},"Down",{"v":1.524704e-09,"d":"1.52E-09"},"ZNF516","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0043565//sequence-specific DNA binding;GO:0000987//proximal promoter sequence-specific DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0033613//activating transcription factor binding;GO:0003676//nucleic acid binding","GO:0007165//signal transduction;GO:0009409//response to cold;GO:0007275//multicellular organism development;GO:0050873//brown fat cell differentiation;GO:0060612//adipose tissue development;GO:0006366//transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","NP_055458.1//zinc finger protein 516 [Homo sapiens]","3//A2MP1"]
[2257,5408,0.47,0.2,-1.23266075679027,0.0111969753,"*",0.00392532,"FGF12","GO:0005634//nucleus;GO:0005615//extracellular space;GO:0005622//intracellular","GO:0044325//ion channel binding;GO:0008083//growth factor activity;GO:0017080//sodium channel regulator activity;GO:0008201//heparin binding","GO:0007399//nervous system development;GO:0008344//adult locomotory behavior;GO:1905150//regulation of voltage-gated sodium channel activity;GO:2000649//regulation of sodium ion transmembrane transporter activity;GO:0003254//regulation of membrane depolarization;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0007165//signal transduction;GO:0007507//heart development;GO:0007267//cell-cell signaling;GO:0086002//cardiac muscle cell action potential involved in contraction;GO:0010765//positive regulation of sodium ion transport;GO:0098908//regulation of neuronal action potential;GO:0007254//JNK cascade;GO:2001258//negative regulation of cation channel activity;GO:1902305//regulation of sodium ion transmembrane transport;GO:0007268//chemical synaptic transmission;GO:0050905//neuromuscular process","K04358//fibroblast growth factor","NP_004104.3//fibroblast growth factor 12 isoform 2 [Homo sapiens];NP_066360.1//fibroblast growth factor 12 isoform 1 [Homo sapiens]","4;5"]
[3764,2406,0.07,0.03,-1.22239242133645,0.734079826584507,"*",0.626454,"KCNJ8","GO:0008282//inward rectifying potassium channel;GO:0030016//myofibril;GO:0005887//integral component of plasma membrane;GO:0042383//sarcolemma;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex","GO:0005524//ATP binding;GO:0017098//sulfonylurea receptor binding;GO:0005242//inward rectifier potassium channel activity;GO:1902282//voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization;GO:0015272//ATP-activated inward rectifier potassium channel activity","GO:0006813//potassium ion transport;GO:0009268//response to pH;GO:0001822//kidney development;GO:0007507//heart development;GO:0051607//defense response to virus;GO:0032496//response to lipopolysaccharide;GO:0043330//response to exogenous dsRNA;GO:0010107//potassium ion import;GO:0098915//membrane repolarization during ventricular cardiac muscle cell action potential;GO:1990573//potassium ion import across plasma membrane;GO:0042311//vasodilation","K05001//potassium inwardly-rectifying channel subfamily J member 8","NP_004973.1//ATP-sensitive inward rectifier potassium channel 8 [Homo sapiens]","3//A2MP1"]
[123591,2414,0.07,0.03,-1.22239242133645,0.730809625063901,"*",0.626454,"TMEM266","GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","NA","NA","K17382//serine beta-lactamase-like protein LACTB, mitochondrial;K13171//serine/arginine repetitive matrix protein 1","NP_689548.2//transmembrane protein 266 [Homo sapiens]","2//1"]
[26751,1806,1.9,0.82,-1.21230360371286,6.87215856900772E-3,"*",0.00228484,"SH3YL1","GO:0032587//ruffle membrane","GO:0019902//phosphatase binding;GO:0035091//phosphatidylinositol binding","GO:1900027//regulation of ruffle assembly;GO:0006661//phosphatidylinositol biosynthetic process","K20523//SH3 domain-containing YSC84-like protein 1","EAX01105.1//hCG1990170, isoform CRA_b, partial [Homo sapiens];XP_009440146.2//PREDICTED: SH3 domain-containing YSC84-like protein 1 isoform X1 [Pan troglodytes]","1//3;3//A2MP1;2//1"]
[6469,2210,0.67,0.29,-1.2081081953302,0.203233057687361,"*",0.1088176,"SHH","GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0009986//cell surface;GO:0005829//cytosol;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0043237//laminin-1 binding;GO:0005113//patched binding;GO:0008233//peptidase activity;GO:0005509//calcium ion binding;GO:0008270//zinc ion binding;GO:0005539//glycosaminoglycan binding;GO:0016015//morphogen activity","GO:0002320//lymphoid progenitor cell differentiation;GO:0043369//CD4-positive or CD8-positive, alpha-beta T cell lineage commitment;GO:0008209//androgen metabolic process;GO:0097190//apoptotic signaling pathway;GO:0051781//positive regulation of cell division;GO:0060840//artery development;GO:0045893//positive regulation of transcription, DNA-templated;GO:1900180//regulation of protein localization to nucleus;GO:0061189//positive regulation of sclerotome development;GO:0060738//epithelial-mesenchymal signaling involved in prostate gland development;GO:0072001//renal system development;GO:0048645//animal organ formation;GO:0016539//intein-mediated protein splicing;GO:0045880//positive regulation of smoothened signaling pathway;GO:0007224//smoothened signaling pathway;GO:0008284//positive regulation of cell proliferation","K11988//sonic hedgehog","NP_001297391.1//sonic hedgehog protein isoform 2 [Homo sapiens];EAX04543.1//sonic hedgehog homolog (Drosophila) [Homo sapiens]","1//3;3//A2MP1"]
[55552,2351,0.85,0.37,-1.19993757050875,0.0483660648648649,"*",0.0203892,"ZNF823","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_016790613.1//PREDICTED: zinc finger protein 823 isoform X3 [Pan troglodytes];XP_014197980.1//PREDICTED: zinc finger protein 823 isoform X1 [Pan paniscus]","1//3;3//A2MP1"]
[94241,5628,1.39,0.61,-1.18820373516062,{"v":1.8254248960396e-05,"d":"1.83E-05"},"Down",{"v":3.69336e-06,"d":"3.69E-06"},"TP53INP1","GO:0016605//PML body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0031410//cytoplasmic vesicle;GO:0005776//autophagosome","GO:0016209//antioxidant activity","GO:0071447//cellular response to hydroperoxide;GO:0006355//regulation of transcription, DNA-templated;GO:0010629//negative regulation of gene expression;GO:0007050//cell cycle arrest;GO:0045893//positive regulation of transcription, DNA-templated;GO:0034644//cellular response to UV;GO:0010506//regulation of autophagy;GO:0048102//autophagic cell death;GO:1904761//negative regulation of myofibroblast differentiation;GO:0008285//negative regulation of cell proliferation;GO:0071361//cellular response to ethanol;GO:0072703//cellular response to methyl methanesulfonate;GO:0006351//transcription, DNA-templated;GO:0030336//negative regulation of cell migration;GO:0010628//positive regulation of gene expression;GO:0009408//response to heat;GO:0048147//negative regulation of fibroblast proliferation;GO:0010508//positive regulation of autophagy;GO:0006915//apoptotic process;GO:1901796//regulation of signal transduction by p53 class mediator;GO:2001235//positive regulation of apoptotic signaling pathway;GO:0042981//regulation of apoptotic process;GO:0000045//autophagosome assembly","K15310//tumor protein p53-inducible nuclear protein 1","NP_001129205.1//tumor protein p53-inducible nuclear protein 1 isoform b [Homo sapiens];NP_150601.1//tumor protein p53-inducible nuclear protein 1 isoform a [Homo sapiens]","1//3;3//A2MP1"]
[54790,9753,0.66,0.29,-1.18641312423088,{"v":8.9891804162103e-05,"d":"8.99E-05"},"Down",{"v":2.05512e-05,"d":"2.06E-05"},"TET2","NA","GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0070579//methylcytosine dioxygenase activity;GO:0008198//ferrous iron binding","GO:0006211//5-methylcytosine catabolic process;GO:0014070//response to organic cyclic compound;GO:0006493//protein O-linked glycosylation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0030099//myeloid cell differentiation;GO:0080182//histone H3-K4 trimethylation;GO:0080111//DNA demethylation;GO:0007049//cell cycle","K11293//protein HIRA/HIR1;K14972//PAX-interacting protein 1;K13097//methylcytosine dioxygenase [EC:1.14.11.-]","NP_001120680.1//methylcytosine dioxygenase TET2 isoform a [Homo sapiens];NP_060098.3//methylcytosine dioxygenase TET2 isoform b [Homo sapiens]","4;2//1"]
[84456,4236,1.42,0.63,-1.17246719600477,0.000199252689425051,"Down",{"v":4.8597e-05,"d":"4.86E-05"},"L3MBTL3","GO:0005634//nucleus;GO:0005730//nucleolus","GO:0008270//zinc ion binding;GO:0003700//DNA binding transcription factor activity","GO:0043249//erythrocyte maturation;GO:0016569//covalent chromatin modification;GO:0030225//macrophage differentiation;GO:0006351//transcription, DNA-templated;GO:0030851//granulocyte differentiation","K11461//polycomb protein SCMH1","NP_115814.1//lethal(3)malignant brain tumor-like protein 3 isoform a [Homo sapiens];NP_001007103.1//lethal(3)malignant brain tumor-like protein 3 isoform b [Homo sapiens]","1//3;3//A2MP1"]
[84765,2943,0.27,0.12,-1.16992500144231,0.306120235199322,"*",0.1807516,"ZNF577","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","XP_014649658.1//PREDICTED: zinc finger protein 613-like [Ceratotherium simum simum];XP_014587901.1//PREDICTED: zinc finger protein 613 [Equus caballus]","1//3;2//1"]
[114792,3138,0.09,0.04,-1.16992500144231,0.529901286306322,"*",0.376212,"KLHL32","GO:0005737//cytoplasm;GO:0031463//Cul3-RING ubiquitin ligase complex","NA","GO:0009566//fertilization;GO:0016567//protein ubiquitination;GO:0007286//spermatid development;GO:0008584//male gonad development","K10468//kelch-like protein 32","XP_012299691.1//kelch-like protein 32 isoform X3 [Aotus nancymaae];NP_001310193.1//kelch-like protein 32 isoform o [Homo sapiens];NP_001310183.1//kelch-like protein 32 isoform g [Homo sapiens];XP_012299692.1//kelch-like protein 32 isoform X4 [Aotus nancymaae];NP_001310184.1//kelch-like protein 32 isoform h [Homo sapiens];XP_009449960.1//PREDICTED: kelch-like protein 32 isoform X1 [Pan troglodytes];NP_001310185.1//kelch-like protein 32 isoform i [Homo sapiens];XP_004580423.1//PREDICTED: kelch-like protein 32 isoform X1 [Ochotona princeps];NP_001310182.1//kelch-like protein 32 isoform f [Homo sapiens];NP_001273181.1//kelch-like protein 32 isoform d [Homo sapiens];XP_012299689.1//kelch-like protein 32 isoform X1 [Aotus nancymaae];NP_001273180.1//kelch-like protein 32 isoform c [Homo sapiens];XP_016865718.1//PREDICTED: kelch-like protein 32 isoform X3 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[55789,2516,8.73,3.9,-1.16250752987983,{"v":1.93748543929712e-13,"d":"1.94E-13"},"Down",{"v":1.51855e-14,"d":"1.52E-14"},"DEPDC1B","GO:0005829//cytosol;GO:0005622//intracellular","GO:0005096//GTPase activator activity","GO:0030177//positive regulation of Wnt signaling pathway;GO:0016477//cell migration;GO:0007165//signal transduction;GO:0035556//intracellular signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction","K20640//Rho GTPase-activating protein 19","XP_517749.3//PREDICTED: DEP domain-containing protein 1B isoform X1 [Pan troglodytes];XP_016808771.1//PREDICTED: DEP domain-containing protein 1B isoform X2 [Pan troglodytes]","1//3;2//1"]
[79827,2955,4.78,2.14,-1.1593998215796,{"v":5.44623474718526e-09,"d":"5.45E-09"},"Down",{"v":6.66204e-10,"d":"6.66E-10"},"CLMP","GO:0070062//extracellular exosome;GO:0009986//cell surface;GO:0005881//cytoplasmic microtubule;GO:0005923//bicellular tight junction;GO:0016021//integral component of membrane","NA","GO:0048565//digestive tract development","K06789//adipocyte-specific adhesion molecule","XP_012500334.1//PREDICTED: CXADR-like membrane protein [Propithecus coquereli]","3//A2MP1"]
[91461,2517,10.76,4.85,-1.14962142548213,{"v":4.2017235859375e-16,"d":"4.20E-16"},"Down",{"v":2.69348e-17,"d":"2.69E-17"},"PKDCC","GO:0005794//Golgi apparatus;GO:0005576//extracellular region","GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity","GO:0030282//bone mineralization;GO:0030154//cell differentiation;GO:0042997//negative regulation of Golgi to plasma membrane protein transport;GO:0035108//limb morphogenesis;GO:0032332//positive regulation of chondrocyte differentiation;GO:0035264//multicellular organism growth;GO:0030501//positive regulation of bone mineralization;GO:0048566//embryonic digestive tract development;GO:0048286//lung alveolus development;GO:0060021//palate development;GO:0001501//skeletal system development;GO:0015031//protein transport;GO:0018108//peptidyl-tyrosine phosphorylation","K17548//protein kinase domain-containing protein, cytoplasmic","NP_612379.2//extracellular tyrosine-protein kinase PKDCC precursor [Homo sapiens]","2//1"]
[2277,2084,0.42,0.19,-1.14438990933517,0.254688314370795,"*",0.1445636,"VEGFD","GO:0031093//platelet alpha granule lumen;GO:0016020//membrane;GO:0005615//extracellular space;GO:0005576//extracellular region","GO:0043185//vascular endothelial growth factor receptor 3 binding;GO:0005161//platelet-derived growth factor receptor binding;GO:0008083//growth factor activity;GO:0005172//vascular endothelial growth factor receptor binding;GO:0042803//protein homodimerization activity;GO:0042056//chemoattractant activity","GO:0050930//induction of positive chemotaxis;GO:0001525//angiogenesis;GO:0051781//positive regulation of cell division;GO:0071542//dopaminergic neuron differentiation;GO:0001666//response to hypoxia;GO:0002576//platelet degranulation;GO:0008283//cell proliferation;GO:0060754//positive regulation of mast cell chemotaxis;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0045766//positive regulation of angiogenesis;GO:0001938//positive regulation of endothelial cell proliferation;GO:0008284//positive regulation of cell proliferation","K05449//vascular endothelial growth factor C/D","NP_004460.1//vascular endothelial growth factor D preproprotein [Homo sapiens]",4]
[8794,1494,1.08,0.49,-1.14017765804826,0.0935732942799189,"*",0.0433188,"TNFRSF10C","GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0031225//anchored component of membrane","GO:0045569//TRAIL binding;GO:0004888//transmembrane signaling receptor activity;GO:0005031//tumor necrosis factor-activated receptor activity","GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007165//signal transduction;GO:0007275//multicellular organism development;GO:0097190//apoptotic signaling pathway;GO:0042127//regulation of cell proliferation;GO:0006955//immune response;GO:0032496//response to lipopolysaccharide;GO:0042981//regulation of apoptotic process;GO:0006954//inflammatory response","K04722//tumor necrosis factor receptor superfamily member 10","AAB71413.1//cytotoxic TRAIL receptor-3 [Homo sapiens]",4]
[10349,6348,0.11,0.05,-1.13750352374993,0.306217632665182,"*",0.1807516,"ABCA10","GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane","GO:0005524//ATP binding;GO:0042626//ATPase activity, coupled to transmembrane movement of substances","GO:0006869//lipid transport","K05652//ATP-binding cassette, subfamily A (ABC1), member 10","NP_525021.3//ATP-binding cassette sub-family A member 10 [Homo sapiens]","3//A2MP1"]
[133522,10602,1.01,0.46,-1.13464952669478,{"v":7.38291810558767e-07,"d":"7.38E-07"},"Down",{"v":1.199366E-7,"d":"1.20E-07"},"PPARGC1B","GO:0005634//nucleus;GO:0016592//mediator complex;GO:0005739//mitochondrion","GO:0030546//receptor activator activity;GO:0003723//RNA binding;GO:0030331//estrogen receptor binding;GO:0050682//AF-2 domain binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0003712//transcription cofactor activity;GO:0008134//transcription factor binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0034614//cellular response to reactive oxygen species;GO:0006355//regulation of transcription, DNA-templated;GO:0051591//response to cAMP;GO:0045672//positive regulation of osteoclast differentiation;GO:0001503//ossification;GO:0045780//positive regulation of bone resorption;GO:0006390//transcription from mitochondrial promoter;GO:0007015//actin filament organization;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0042327//positive regulation of phosphorylation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0060346//bone trabecula formation;GO:0010694//positive regulation of alkaline phosphatase activity;GO:0051384//response to glucocorticoid","K17962//peroxisome proliferator-activated receptor gamma coactivator 1-beta","NP_573570.3//peroxisome proliferator-activated receptor gamma coactivator 1-beta isoform 1 [Homo sapiens];NP_001166169.1//peroxisome proliferator-activated receptor gamma coactivator 1-beta isoform 2 [Homo sapiens];NP_001166170.1//peroxisome proliferator-activated receptor gamma coactivator 1-beta isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[54874,4382,5.61,2.57,-1.12623241141491,{"v":1.33505811471415e-15,"d":"1.34E-15"},"Down",{"v":8.91766e-17,"d":"8.92E-17"},"FNBP1L","GO:0070062//extracellular exosome;GO:0005856//cytoskeleton;GO:0005938//cell cortex;GO:0005829//cytosol;GO:0031410//cytoplasmic vesicle;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0008289//lipid binding;GO:0051020//GTPase binding;GO:0045296//cadherin binding","GO:0051491//positive regulation of filopodium assembly;GO:0072583//clathrin-dependent endocytosis;GO:0006900//vesicle budding from membrane;GO:0061024//membrane organization;GO:0010324//membrane invagination;GO:0016050//vesicle organization;GO:0060271//cilium assembly;GO:0006897//endocytosis;GO:0006914//autophagy;GO:0097320//plasma membrane tubulation;GO:0030050//vesicle transport along actin filament","K20121//formin-binding protein 1","NP_060207.2//formin-binding protein 1-like isoform 2 [Homo sapiens];NP_001020119.1//formin-binding protein 1-like isoform 1 [Homo sapiens];NP_001157945.1//formin-binding protein 1-like isoform 3 [Homo sapiens]","4;2//1"]
[57519,15584,0.78,0.36,-1.11547721741994,{"v":1.26833971877954E-7,"d":"1.27E-07"},"Down",{"v":1.847644e-08,"d":"1.85E-08"},"STARD9","GO:0005814//centriole;GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0005524//ATP binding;GO:0015485//cholesterol binding;GO:0003777//microtubule motor activity;GO:0008017//microtubule binding","GO:0007018//microtubule-based movement;GO:0008152//metabolic process;GO:0051225//spindle assembly","K16491//StAR-related lipid transfer protein 9","NP_065810.2//stAR-related lipid transfer protein 9 [Homo sapiens]","2//1"]
[8497,6461,0.26,0.12,-1.11547721741994,0.107309161927456,"*",0.0507458,"PPFIA4","GO:0048786//presynaptic active zone;GO:0009986//cell surface;GO:0005829//cytosol;GO:0005622//intracellular;GO:0045202//synapse","NA","GO:0007269//neurotransmitter secretion;GO:0014047//glutamate secretion","K07762//pappalysin-1 [EC:3.4.24.79];K06236//collagen, type I, alpha","NP_001291261.1//liprin-alpha-4 isoform 2 [Homo sapiens];NP_001291260.1//liprin-alpha-4 isoform 1 [Homo sapiens]","1//3"]
[54492,5833,2,0.93,-1.10469737866669,{"v":5.87715207227023e-07,"d":"5.88E-07"},"Down",{"v":9.36724e-08,"d":"9.37E-08"},"NEURL1B","GO:0005769//early endosome","GO:0046872//metal ion binding;GO:0016740//transferase activity;GO:0016874//ligase activity","GO:0016567//protein ubiquitination;GO:0007219//Notch signaling pathway;GO:0070086//ubiquitin-dependent endocytosis","K01931//protein neuralized [EC:2.3.2.27]","NP_001295107.1//E3 ubiquitin-protein ligase NEURL1B isoform hNEUR2-deltaNHR2 [Homo sapiens];NP_001136123.1//E3 ubiquitin-protein ligase NEURL1B isoform hNEUR2 [Homo sapiens];NP_001295106.1//E3 ubiquitin-protein ligase NEURL1B isoform hNEUR2-deltaNHR1 [Homo sapiens]","1//3;2//1"]
[23439,4773,0.94,0.44,-1.09515723304034,2.93996275203252E-3,"*",9.0551E-4,"ATP1B4","GO:0005890//sodium:potassium-exchanging ATPase complex;GO:0005637//nuclear inner membrane","NA","GO:0006813//potassium ion transport;GO:0006355//regulation of transcription, DNA-templated;GO:0006814//sodium ion transport","K01540//sodium/potassium-transporting ATPase subunit beta","XP_012594504.1//protein ATP1B4 isoform X1 [Microcebus murinus];XP_012594514.1//protein ATP1B4 isoform X2 [Microcebus murinus]","4;2//1"]
[4137,5660,0.79,0.37,-1.09432738254815,0.00159055350850743,"*",0.00046231,"MAPT","GO:0030424//axon;GO:1904115//axon cytoplasm;GO:0005874//microtubule;GO:0016607//nuclear speck;GO:0030673//axolemma;GO:0005737//cytoplasm;GO:0043005//neuron projection;GO:0044297//cell body;GO:0005875//microtubule associated complex;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0003779//actin binding;GO:0034452//dynactin binding;GO:0003677//DNA binding;GO:0034185//apolipoprotein binding;GO:0008017//microtubule binding","GO:0000226//microtubule cytoskeleton organization;GO:1990000//amyloid fibril formation;GO:0031175//neuron projection development;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0098930//axonal transport;GO:0048143//astrocyte activation","K04380//microtubule-associated protein tau","NP_001116539.1//microtubule-associated protein tau isoform 5 [Homo sapiens];NP_058518.1//microtubule-associated protein tau isoform 3 [Homo sapiens];NP_058519.3//microtubule-associated protein tau isoform 1 [Homo sapiens];NP_058525.1//microtubule-associated protein tau isoform 4 [Homo sapiens];NP_005901.2//microtubule-associated protein tau isoform 2 [Homo sapiens];NP_001190180.1//microtubule-associated protein tau isoform 7 [Homo sapiens];NP_001116538.2//microtubule-associated protein tau isoform 6 [Homo sapiens];NP_001190181.1//microtubule-associated protein tau isoform 8 [Homo sapiens]","1//3;4;3//A2MP1;5"]
[79925,3364,0.66,0.31,-1.09019780897158,0.0346578953908314,"*",0.01396166,"SPEF2","NA","NA","NA","K20045//intersectin;K18626//trichohyalin;K11515//inner centromere protein;K20478//golgin subfamily B member 1","NP_079143.3//sperm flagellar protein 2 isoform 1 [Homo sapiens];NP_653323.1//sperm flagellar protein 2 isoform 2 [Homo sapiens]","3//A2MP1"]
[5080,6732,1.1,0.52,-1.08091999538357,0.282329642736523,"*",0.1632754,"PAX6","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0000790//nuclear chromatin;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0070410//co-SMAD binding;GO:0003682//chromatin binding;GO:0043565//sequence-specific DNA binding;GO:0035035//histone acetyltransferase binding","GO:0048708//astrocyte differentiation;GO:0009887//animal organ morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0007275//multicellular organism development;GO:0006351//transcription, DNA-templated;GO:0001568//blood vessel development;GO:0007411//axon guidance","K08031//paired box protein 6","XP_014313762.1//PREDICTED: paired box protein Pax-6 isoform X1 [Myotis lucifugus];XP_013358393.1//PREDICTED: paired box protein Pax-6 isoform X3 [Chinchilla lanigera];XP_008001416.1//PREDICTED: paired box protein Pax-6 isoform X1 [Chlorocebus sabaeus];XP_013358392.1//PREDICTED: paired box protein Pax-6 isoform X1 [Chinchilla lanigera];XP_020934291.1//paired box protein Pax-6 isoform X1 [Sus scrofa]","4;1//3;5"]
[221191,1632,0.74,0.35,-1.08017034868398,0.179726705491087,"*",0.0940488,"PRSS54","GO:0005576//extracellular region","GO:0004252//serine-type endopeptidase activity","NA","K01317//acrosin [EC:3.4.21.10];K01324//plasma kallikrein [EC:3.4.21.34]","XP_016783984.1//PREDICTED: inactive serine protease 54 isoform X1 [Pan troglodytes];NP_001073961.1//inactive serine protease 54 isoform 1 precursor [Homo sapiens]","1//3"]
[10896,884,0.19,0.09,-1.07800251200127,0.730702898576123,"*",0.626454,"OCLM","GO:0016021//integral component of membrane","NA","GO:0007601//visual perception","NA","NP_071770.1//oculomedin [Homo sapiens]","3//A2MP1"]
[57600,6883,1.01,0.48,-1.07324898203064,0.000210418954743032,"Down",{"v":5.1518e-05,"d":"5.15E-05"},"FNIP2","NA","NA","NA","K20401//folliculin-interacting protein 2","XP_004040620.2//PREDICTED: folliculin-interacting protein 2 isoform X3 [Gorilla gorilla gorilla];XP_018881229.1//PREDICTED: folliculin-interacting protein 2 isoform X2 [Gorilla gorilla gorilla];XP_011530456.1//PREDICTED: folliculin-interacting protein 2 isoform X4 [Homo sapiens]","1//3;2//1"]
[22837,9406,0.61,0.29,-1.07275634243531,0.000890943717253839,"Down",2.4697E-4,"COBLL1","GO:0070062//extracellular exosome","GO:0003779//actin binding;GO:0003785//actin monomer binding;GO:0045296//cadherin binding","GO:0051639//actin filament network formation;GO:0030041//actin filament polymerization","K18623//protein cordon-bleu","NP_001265389.1//cordon-bleu protein-like 1 isoform 3 [Homo sapiens];Q53SF7.2//RecName: Full=Cordon-bleu protein-like 1;NP_001265387.1//cordon-bleu protein-like 1 isoform 1 [Homo sapiens]","4;1//3"]
[199786,2166,0.23,0.11,-1.06413033741972,0.499591840970839,"*",0.345342,"FAM129C","NA","NA","NA","K16145//mucin-16;K16628//collagen, type VII, alpha;K06236//collagen, type I, alpha","NP_775815.2//niban-like protein 2 isoform a [Homo sapiens];NP_001091994.1//niban-like protein 2 isoform b [Homo sapiens];NP_001308755.1//niban-like protein 2 isoform c [Homo sapiens]","1//3;4"]
[3199,1791,2.25,1.08,-1.05889368905357,0.00749054787607316,"*",0.00251248,"HOXA2","NA","NA","NA","K09302//homeobox protein HoxA/B2","XP_017501981.1//PREDICTED: homeobox protein Hox-A2 [Manis javanica]","3//A2MP1"]
[10484,4188,19.93,9.57,-1.05835088035303,{"v":1.59515095306859E-42,"d":"1.60E-42"},"Down",{"v":2.7661e-44,"d":"2.77E-44"},"SEC23A","GO:0070971//endoplasmic reticulum exit site;GO:0019898//extrinsic component of membrane;GO:0048471//perinuclear region of cytoplasm;GO:0000139//Golgi membrane;GO:0030127//COPII vesicle coat;GO:0005829//cytosol;GO:0005789//endoplasmic reticulum membrane;GO:0012507//ER to Golgi transport vesicle membrane","GO:0008270//zinc ion binding","GO:0006886//intracellular protein transport;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0048208//COPII vesicle coating;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0090110//cargo loading into COPII-coated vesicle;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I","K14006//protein transport protein SEC23","NP_006355.2//protein transport protein Sec23A [Homo sapiens]","3//A2MP1"]
[349149,1131,0.29,0.14,-1.05062607306997,0.61105690115252,"*",0.454716,"GJC3","GO:0005922//connexin complex;GO:0043209//myelin sheath;GO:0016021//integral component of membrane","GO:0042803//protein homodimerization activity","GO:0042552//myelination;GO:0007605//sensory perception of sound;GO:0007154//cell communication","K07628//gap junction gamma-3 protein","NP_853516.1//gap junction gamma-3 protein [Homo sapiens]","2//1"]
[346606,1207,0.31,0.15,-1.04730571477836,0.611211156512959,"*",0.454716,"MOGAT3","GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0003846//2-acylglycerol O-acyltransferase activity;GO:0004144//diacylglycerol O-acyltransferase activity;GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups","GO:0006071//glycerol metabolic process;GO:0019432//triglyceride biosynthetic process","K14456//2-acylglycerol O-acyltransferase 3 [EC:2.3.1.20 2.3.1.22]","NP_001274076.1//2-acylglycerol O-acyltransferase 3 isoform b [Homo sapiens];NP_835470.1//2-acylglycerol O-acyltransferase 3 isoform a [Homo sapiens]","1//3;3//A2MP1"]
[64168,5140,0.31,0.15,-1.04730571477836,0.142627760369123,"*",0.0715996,"NECAB1","NA","NA","NA","NA","XP_009453893.2//PREDICTED: N-terminal EF-hand calcium-binding protein 1 [Pan troglodytes]",4]
[901,5489,1.15,0.56,-1.03813512888677,0.000615240102897196,"Down",1.648446E-4,"CCNG2","GO:0005737//cytoplasm","NA","GO:0000075//cell cycle checkpoint;GO:0051301//cell division;GO:0051726//regulation of cell cycle;GO:0007049//cell cycle","K10146//cyclin G2","NP_004345.1//cyclin-G2 [Homo sapiens]","2//1"]
[3384,1153,0.43,0.21,-1.03394733192334,0.499365719923961,"*",0.345342,"ICAM2","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005887//integral component of plasma membrane;GO:0032154//cleavage furrow;GO:0001931//uropod;GO:0005886//plasma membrane","GO:0005178//integrin binding","GO:0007155//cell adhesion;GO:0030198//extracellular matrix organization;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0050776//regulation of immune response","K06523//intercellular adhesion molecule 2","XP_012357006.1//PREDICTED: intercellular adhesion molecule 2 isoform X1 [Nomascus leucogenys];BAD93115.1//intercellular adhesion molecule 2 precursor variant, partial [Homo sapiens]","1//3;3//A2MP1"]
[3156,4534,10.8,5.29,-1.02969168493681,{"v":1.91341294747826E-24,"d":"1.91E-24"},"Down",{"v":6.88752e-26,"d":"6.89E-26"},"HMGCR","GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005778//peroxisomal membrane","GO:0050661//NADP binding;GO:0004420//hydroxymethylglutaryl-CoA reductase (NADPH) activity;GO:0051721//protein phosphatase 2A binding;GO:0042803//protein homodimerization activity;GO:0070402//NADPH binding;GO:0042282//hydroxymethylglutaryl-CoA reductase activity;GO:0050662//coenzyme binding","GO:0008542//visual learning;GO:0043407//negative regulation of MAP kinase activity;GO:0015936//coenzyme A metabolic process;GO:0045471//response to ethanol;GO:0045540//regulation of cholesterol biosynthetic process;GO:0097756//negative regulation of blood vessel diameter;GO:0010664//negative regulation of striated muscle cell apoptotic process;GO:0045445//myoblast differentiation;GO:0007584//response to nutrient;GO:0019216//regulation of lipid metabolic process;GO:0010666//positive regulation of cardiac muscle cell apoptotic process;GO:0061045//negative regulation of wound healing;GO:0008299//isoprenoid biosynthetic process;GO:0061179//negative regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0006695//cholesterol biosynthetic process;GO:0032874//positive regulation of stress-activated MAPK cascade;GO:0051262//protein tetramerization;GO:0007568//aging;GO:0048643//positive regulation of skeletal muscle tissue development;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0006743//ubiquinone metabolic process","K00021//hydroxymethylglutaryl-CoA reductase (NADPH) [EC:1.1.1.34]","XP_011541659.1//PREDICTED: 3-hydroxy-3-methylglutaryl-Coenzyme A reductase isoform X1 [Homo sapiens];XP_011541661.1//PREDICTED: 3-hydroxy-3-methylglutaryl-Coenzyme A reductase isoform X3 [Homo sapiens]","1//3;2//1"]
[54454,8099,1.2,0.59,-1.02424754624668,{"v":1.64991017071651e-05,"d":"1.65E-05"},"Down",{"v":3.31552E-6,"d":"3.32E-06"},"ATAD2B","GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0042393//histone binding;GO:0005524//ATP binding;GO:0003682//chromatin binding;GO:0070577//lysine-acetylated histone binding;GO:0016887//ATPase activity","GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0031936//negative regulation of chromatin silencing","K14575//AAA family ATPase;K13525//transitional endoplasmic reticulum ATPase","NP_001341036.1//ATPase family AAA domain-containing protein 2B isoform 3 [Homo sapiens];NP_001229267.2//ATPase family AAA domain-containing protein 2B isoform 2 [Homo sapiens];NP_060022.2//ATPase family AAA domain-containing protein 2B isoform 1 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[389649,2077,1.56,0.77,-1.01861567816735,0.0172454121745035,"*",6.35988E-3,"C8orf86","NA","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K04487//cysteine desulfurase [EC:2.8.1.7];K01064//wingless-type MMTV integration site family, member 9","XP_001171412.2//PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein C8orf86 homolog [Pan troglodytes];NP_001290460.1//uncharacterized protein C8orf86 isoform 2 [Homo sapiens]","1//3;2//1"]
[23348,7493,3.2,1.58,-1.01814734671026,{"v":1.18912772339261E-11,"d":"1.19E-11"},"Down",{"v":1.088334E-12,"d":"1.09E-12"},"DOCK9","GO:0016020//membrane;GO:0012505//endomembrane system;GO:0005829//cytosol;GO:0005622//intracellular","GO:0005085//guanyl-nucleotide exchange factor activity;GO:0045296//cadherin binding","GO:0007596//blood coagulation;GO:0007264//small GTPase mediated signal transduction;GO:0043547//positive regulation of GTPase activity","K21853//dedicator of cytokinesis protein 9/10/11","EAX08996.1//dedicator of cytokinesis 9, isoform CRA_c [Homo sapiens];NP_001123521.1//dedicator of cytokinesis protein 9 isoform c [Homo sapiens];NP_001123522.1//dedicator of cytokinesis protein 9 isoform d [Homo sapiens];NP_001123520.1//dedicator of cytokinesis protein 9 isoform b [Homo sapiens];EAX09003.1//dedicator of cytokinesis 9, isoform CRA_j [Homo sapiens]","1//3;2//1"]
[1184,9839,1.25,0.62,-1.01158797427521,{"v":2.45735163623446e-06,"d":"2.46E-06"},"Down",{"v":4.33044e-07,"d":"4.33E-07"},"CLCN5","GO:0005765//lysosomal membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0045177//apical part of cell;GO:0005886//plasma membrane","GO:0042802//identical protein binding;GO:0005247//voltage-gated chloride channel activity","NA","K05012//chloride channel 3/4/5","NP_001259031.1//H(+)/Cl(-) exchange transporter 5 isoform c [Homo sapiens];XP_012666732.1//PREDICTED: H(+)/Cl(-) exchange transporter 5 isoform X1 [Otolemur garnettii]","4;1//3;3//A2MP1"]
[4293,11120,3.18,1.58,-1.00910220710725,{"v":1.90237868320856e-17,"d":"1.90E-17"},"Down",{"v":1.113512E-18,"d":"1.11E-18"},"MAP3K9","GO:0016021//integral component of membrane;GO:0005737//cytoplasm","GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0004706//JUN kinase kinase kinase activity;GO:0042803//protein homodimerization activity;GO:0004713//protein tyrosine kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004708//MAP kinase kinase activity;GO:0004672//protein kinase activity","GO:0043065//positive regulation of apoptotic process;GO:0006355//regulation of transcription, DNA-templated;GO:0006468//protein phosphorylation;GO:0006351//transcription, DNA-templated;GO:0046777//protein autophosphorylation;GO:0006915//apoptotic process;GO:0007257//activation of JUN kinase activity","K04417//mitogen-activated protein kinase kinase kinase 9 [EC:2.7.11.25]","NP_001271159.1//mitogen-activated protein kinase kinase kinase 9 isoform 2 [Homo sapiens];NP_149132.2//mitogen-activated protein kinase kinase kinase 9 isoform 1 [Homo sapiens];NP_001271160.1//mitogen-activated protein kinase kinase kinase 9 isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[57763,2198,4.01,2,-1.0036022366802,{"v":7.72465334919756e-05,"d":"7.72E-05"},"Down",{"v":1.747646e-05,"d":"1.75E-05"},"ANKRA2","GO:0016020//membrane;GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0043234//protein complex;GO:0005829//cytosol;GO:1990393//3M complex;GO:0005737//cytoplasm","GO:0042826//histone deacetylase binding;GO:0031625//ubiquitin protein ligase binding;GO:0003712//transcription cofactor activity;GO:0050750//low-density lipoprotein particle receptor binding;GO:0019901//protein kinase binding","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0043254//regulation of protein complex assembly","K21486//ankyrin repeat family A protein 2","XP_008539463.1//PREDICTED: ankyrin repeat family A protein 2 isoform X1 [Equus przewalskii]",4]
[56903,4271,0.02,0.01,-1,0.641171607403253,"*",0.500968,"PAPOLB","GO:0005634//nucleus","GO:0003723//RNA binding;GO:0004652//polynucleotide adenylyltransferase activity","GO:0031123//RNA 3'-end processing;GO:0043631//RNA polyadenylation","K14376//poly(A) polymerase [EC:2.7.7.19]","XP_003934837.1//PREDICTED: poly(A) polymerase beta [Saimiri boliviensis boliviensis]",4]
[2706,2347,0.14,0.07,-1,0.611159729406815,"*",0.454716,"GJB2","GO:0005922//connexin complex;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0048471//perinuclear region of cytoplasm;GO:0044297//cell body;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0016328//lateral plasma membrane;GO:0097449//astrocyte projection;GO:0005886//plasma membrane","GO:0005243//gap junction channel activity;GO:0042802//identical protein binding","GO:0032496//response to lipopolysaccharide;GO:0032570//response to progesterone;GO:0046677//response to antibiotic;GO:1905867//epididymis development;GO:0016264//gap junction assembly;GO:0032355//response to estradiol;GO:0048839//inner ear development;GO:0044752//response to human chorionic gonadotropin;GO:0006810//transport;GO:0002931//response to ischemia;GO:0071377//cellular response to glucagon stimulus;GO:0046697//decidualization;GO:0007267//cell-cell signaling;GO:0032526//response to retinoic acid;GO:0007568//aging;GO:0071549//cellular response to dexamethasone stimulus;GO:0034599//cellular response to oxidative stress;GO:0007605//sensory perception of sound","K07621//gap junction beta-2 protein","NP_003995.2//gap junction beta-2 protein [Homo sapiens]",5]
[2615,4222,0.04,0.02,-1,0.73413368028758,"*",0.626454,"LRRC32","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane","NA","GO:0046007//negative regulation of activated T cell proliferation;GO:0010628//positive regulation of gene expression;GO:0050710//negative regulation of cytokine secretion","K17256//insulin-like growth factor-binding protein complex acid labile subunit;K07620//gap junction beta-1 protein","NP_005503.1//leucine-rich repeat-containing protein 32 precursor [Homo sapiens]","1//3;2//1"]
[389857,1620,0.02,0.01,-1,1.00078622651449,"*",0.999032,"CENPVL1","NA","NA","NA","K22020//mucin-19;K16630//collagen, type XXII, alpha","EAW62899.1//hCG1793638, partial [Homo sapiens]","1//3"]
[729159,2115,1.18,0.59,-1,0.0453602738346315,"*",0.01895738,"LOC729159","NA","NA","NA","K06236//collagen, type I, alpha","NP_001269230.1//putative UPF0607 protein ENSP00000381418 [Homo sapiens]","2//1"]
[8706,3342,0.02,0.01,-1,1.00072346949269,"*",0.999032,"B3GALNT1","NA","NA","NA","K00719//galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase [EC:2.4.1.79]","NP_001336091.1//UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1 isoform a [Homo sapiens]","1//3;3//A2MP1;2//1"]
[168620,706,0.24,0.12,-1,0.733595498570486,"*",0.626454,"BHLHA15","GO:0005634//nucleus","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0042803//protein homodimerization activity;GO:0046983//protein dimerization activity","GO:0006851//mitochondrial calcium ion transmembrane transport;GO:0007186//G-protein coupled receptor signaling pathway;GO:0010832//negative regulation of myotube differentiation;GO:0007267//cell-cell signaling;GO:0019722//calcium-mediated signaling;GO:0007030//Golgi organization;GO:0042149//cellular response to glucose starvation;GO:0042593//glucose homeostasis;GO:0048469//cell maturation;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0048312//intracellular distribution of mitochondria","K08040//class B basic helix-loop-helix protein 8","NP_803238.1//class A basic helix-loop-helix protein 15 [Homo sapiens]","3//A2MP1"]
[441495,1620,0.02,0.01,-1,1.00015901027827,"*",0.999032,"CENPVL2","NA","NA","NA","K22020//mucin-19;K16630//collagen, type XXII, alpha","EAW62899.1//hCG1793638, partial [Homo sapiens]","1//3"]
[388553,2754,0.06,0.03,-1,0.732789703866432,"*",0.626454,"BHMG1","GO:0005634//nucleus","GO:0003677//DNA binding;GO:0046983//protein dimerization activity","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K08871//bromodomain-containing protein 2;K14562//Treacher Collins syndrome protein","XP_011525873.1//PREDICTED: basic helix-loop-helix and HMG box domain-containing protein 1 isoform X1 [Homo sapiens]","1//3"]
[9358,3317,0.08,0.04,-1,0.531353712466843,"*",0.376212,"ITGBL1","GO:0005615//extracellular space","NA","GO:0007155//cell adhesion;GO:0007229//integrin-mediated signaling pathway","K06589//integrin beta 6;K06493//integrin beta 3;K06252//tenascin","NP_001258685.1//integrin beta-like protein 1 isoform 3 [Homo sapiens];NP_004782.1//integrin beta-like protein 1 isoform 1 precursor [Homo sapiens];NP_001258684.1//integrin beta-like protein 1 isoform 2 precursor [Homo sapiens];XP_001150034.1//PREDICTED: integrin beta-like protein 1 isoform X1 [Pan troglodytes]","1//3;2//1"]
[83715,3531,0.04,0.02,-1,0.732575124158126,"*",0.626454,"ESPN","GO:0005903//brush border;GO:0032426//stereocilium tip;GO:0005902//microvillus;GO:0005737//cytoplasm;GO:0031941//filamentous actin","GO:0051015//actin filament binding;GO:0017124//SH3 domain binding","GO:0007626//locomotory behavior;GO:0051491//positive regulation of filopodium assembly;GO:0007605//sensory perception of sound;GO:0051017//actin filament bundle assembly;GO:0030046//parallel actin filament bundle assembly;GO:0051494//negative regulation of cytoskeleton organization","K18441//cytohesin","NP_113663.2//espin [Homo sapiens]","2//1"]
[10343,7660,0.02,0.01,-1,0.39188817260274,"*",0.250726,"PKDREJ","GO:0016020//membrane;GO:0016021//integral component of membrane","GO:0005509//calcium ion binding;GO:0005262//calcium channel activity","GO:0007340//acrosome reaction;GO:0050982//detection of mechanical stimulus","K19921//polycystic kidney disease and receptor for egg jelly-related protein","NP_006062.1//polycystic kidney disease and receptor for egg jelly-related protein precursor [Homo sapiens]","1//3"]
[3071,3780,0.02,0.01,-1,0.633256534937089,"*",0.500968,"NCKAP1L","GO:0031209//SCAR complex;GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005829//cytosol","GO:0030295//protein kinase activator activity;GO:0032403//protein complex binding;GO:0005096//GTPase activator activity","GO:0060100//positive regulation of phagocytosis, engulfment;GO:0042102//positive regulation of T cell proliferation;GO:0032715//negative regulation of interleukin-6 production;GO:0030866//cortical actin cytoskeleton organization;GO:0030890//positive regulation of B cell proliferation;GO:0048821//erythrocyte development;GO:0030838//positive regulation of actin filament polymerization;GO:0043372//positive regulation of CD4-positive, alpha-beta T cell differentiation;GO:0035509//negative regulation of myosin-light-chain-phosphatase activity;GO:0050853//B cell receptor signaling pathway;GO:0042493//response to drug;GO:0090023//positive regulation of neutrophil chemotaxis;GO:0030593//neutrophil chemotaxis;GO:0070358//actin polymerization-dependent cell motility;GO:0043066//negative regulation of apoptotic process;GO:0045579//positive regulation of B cell differentiation;GO:0043029//T cell homeostasis;GO:0032700//negative regulation of interleukin-17 production;GO:0045588//positive regulation of gamma-delta T cell differentiation;GO:0045648//positive regulation of erythrocyte differentiation;GO:0043378//positive regulation of CD8-positive, alpha-beta T cell differentiation;GO:0001782//B cell homeostasis;GO:0006461//protein complex assembly;GO:0033630//positive regulation of cell adhesion mediated by integrin;GO:0030011//maintenance of cell polarity","K05750//NCK-associated protein 1","XP_010372155.1//PREDICTED: nck-associated protein 1-like [Rhinopithecus roxellana]","1//3;4"]
[401145,3927,0.02,0.01,-1,0.99984569688616,"*",0.999032,"CCSER1","NA","NA","NA","NA","NP_997374.1//serine-rich coiled-coil domain-containing protein 1 isoform 2 [Homo sapiens];NP_001138537.1//serine-rich coiled-coil domain-containing protein 1 isoform 1 [Homo sapiens]","1//3;2//1"]
[2525,2342,0.06,0.03,-1,0.731985677419355,"*",0.626454,"FUT3","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0032580//Golgi cisterna membrane;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0046920//alpha-(1->3)-fucosyltransferase activity;GO:0008417//fucosyltransferase activity;GO:0017060//3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity","GO:0006486//protein glycosylation;GO:0043413//macromolecule glycosylation;GO:0009988//cell-cell recognition;GO:0009312//oligosaccharide biosynthetic process;GO:0006672//ceramide metabolic process","K00716//galactoside 3(4)-fucosyltransferase 3 [EC:2.4.1.65]","NP_000140.1//galactoside 3(4)-L-fucosyltransferase [Homo sapiens]","1//3;3//A2MP1"]
[286530,4240,0.02,0.01,-1,0.631358014358974,"*",0.500968,"P2RY8","GO:0005887//integral component of plasma membrane","GO:0045028//G-protein coupled purinergic nucleotide receptor activity;GO:0004930//G-protein coupled receptor activity","GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway;GO:0035025//positive regulation of Rho protein signal transduction","K08386//purinergic receptor P2Y, G protein-coupled, 8","XP_006724506.2//PREDICTED: P2Y purinoceptor 8 isoform X1 [Homo sapiens]",4]
[1620,3196,0.02,0.01,-1,0.631208615870011,"*",0.500968,"BRINP1","GO:0030425//dendrite;GO:0005783//endoplasmic reticulum;GO:0005737//cytoplasm;GO:0043025//neuronal cell body","NA","GO:0050768//negative regulation of neurogenesis;GO:0035176//social behavior;GO:0045666//positive regulation of neuron differentiation;GO:0045930//negative regulation of mitotic cell cycle;GO:0045786//negative regulation of cell cycle;GO:0008219//cell death;GO:0007050//cell cycle arrest;GO:0001662//behavioral fear response;GO:0071300//cellular response to retinoic acid;GO:0035640//exploration behavior;GO:0071625//vocalization behavior;GO:0007614//short-term memory;GO:0042711//maternal behavior","K15164//mediator of RNA polymerase II transcription subunit 13;K21125//mucin-5AC","NP_055433.2//BMP/retinoic acid-inducible neural-specific protein 1 precursor [Homo sapiens]","2//1"]
[100652824,4147,0.02,0.01,-1,0.63076084432884,"*",0.500968,"KIAA2012","NA","NA","NA","K12484//Rab11 family-interacting protein 1/2/5;K18626//trichohyalin","XP_006712235.1//PREDICTED: uncharacterized protein KIAA2012 isoform X3 [Homo sapiens]","2//1"]
[55567,12528,0.02,0.01,-1,0.530415753574581,"*",0.376212,"DNAH3","NA","NA","NA","K10408//dynein heavy chain, axonemal","XP_018868309.1//PREDICTED: dynein heavy chain 3, axonemal [Gorilla gorilla gorilla]","1//3;2//1"]
[8483,4484,0.04,0.02,-1,0.731129991670929,"*",0.626454,"CILP","GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005578//proteinaceous extracellular matrix","NA","GO:0043569//negative regulation of insulin-like growth factor receptor signaling pathway","K19031//cell migration-inducing and hyaluronan-binding protein [EC:3.2.1.35]","NP_003604.3//cartilage intermediate layer protein 1 preproprotein [Homo sapiens]","3//A2MP1"]
[57619,11023,0.96,0.48,-1,{"v":1.07702490629012E-5,"d":"1.08E-05"},"Down",{"v":2.10092e-06,"d":"2.10E-06"},"SHROOM3","GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0016324//apical plasma membrane;GO:0043296//apical junction complex;GO:0005737//cytoplasm;GO:0005912//adherens junction","GO:0051015//actin filament binding","GO:0007389//pattern specification process;GO:0000902//cell morphogenesis;GO:0002064//epithelial cell development;GO:0001843//neural tube closure;GO:0008360//regulation of cell shape;GO:0043482//cellular pigment accumulation;GO:0045176//apical protein localization","K18625//protein Shroom","NP_065910.3//protein Shroom3 [Homo sapiens]","3//A2MP1"]
[54887,9658,2.48,1.24,-1,{"v":9.14757807345807e-12,"d":"9.15E-12"},"Down",{"v":8.2634e-13,"d":"8.26E-13"},"UHRF1BP1","NA","GO:0042802//identical protein binding;GO:0042826//histone deacetylase binding","NA","K06245//laminin, beta 4;K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K04613//vomeronasal 2 receptor;K12025//tripartite motif-containing protein 52","NP_060224.3//UHRF1-binding protein 1 [Homo sapiens]","3//A2MP1"]
[84688,1095,0.6,0.3,-1,1.01671034732678,"*",0.997616,"C9orf24","GO:0005634//nucleus;GO:0002177//manchette;GO:0048471//perinuclear region of cytoplasm","GO:0043014//alpha-tubulin binding","GO:0030154//cell differentiation;GO:0007283//spermatogenesis;GO:0043623//cellular protein complex assembly","K18634//spermatid-specific manchette-related protein 1","XP_003829848.1//PREDICTED: spermatid-specific manchette-related protein 1 isoform X3 [Pan paniscus];NP_115985.2//spermatid-specific manchette-related protein 1 isoform 1 [Homo sapiens];XP_008953425.1//PREDICTED: spermatid-specific manchette-related protein 1 isoform X2 [Pan paniscus];EAW58459.1//chromosome 9 open reading frame 24, isoform CRA_d [Homo sapiens]","1//3;3//A2MP1;2//1"]
[55613,2675,0.18,0.09,-1,0.498688583258,"*",0.345342,"MTMR8","GO:0005635//nuclear envelope;GO:0005829//cytosol","GO:0004725//protein tyrosine phosphatase activity;GO:0004438//phosphatidylinositol-3-phosphatase activity;GO:0052629//phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity","GO:0010506//regulation of autophagy;GO:0006661//phosphatidylinositol biosynthetic process;GO:0046856//phosphatidylinositol dephosphorylation","K18083//myotubularin-related protein 6/7/8 [EC:3.1.3.64 3.1.3.95]","NP_060147.2//myotubularin-related protein 8 [Homo sapiens]","3//A2MP1"]
[440854,3841,0.02,0.01,-1,0.626170800625978,"*",0.500968,"CAPN14","GO:0005622//intracellular;GO:0005737//cytoplasm","GO:0004198//calcium-dependent cysteine-type endopeptidase activity;GO:0005509//calcium ion binding","GO:0006508//proteolysis","K13442//calpain-14 [EC:3.4.22.-]","NP_001308199.1//calpain-14 isoform 2 [Homo sapiens];NP_001138594.1//calpain-14 isoform 1 [Homo sapiens]","1//3"]
[324,10448,2.32,1.16,-1,{"v":3.47541069727403E-12,"d":"3.48E-12"},"Down",{"v":3.03288e-13,"d":"3.03E-13"},"APC","GO:0005874//microtubule;GO:0030877//beta-catenin destruction complex;GO:0032587//ruffle membrane;GO:0005737//cytoplasm;GO:0005913//cell-cell adherens junction;GO:0005829//cytosol;GO:0005923//bicellular tight junction;GO:0016328//lateral plasma membrane;GO:0005886//plasma membrane;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005813//centrosome;GO:0005912//adherens junction;GO:0030027//lamellipodium;GO:0048471//perinuclear region of cytoplasm;GO:0016342//catenin complex;GO:1990909//Wnt signalosome;GO:0000776//kinetochore","GO:0045295//gamma-catenin binding;GO:0070840//dynein complex binding;GO:0042802//identical protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0008017//microtubule binding;GO:0019901//protein kinase binding;GO:0019887//protein kinase regulator activity;GO:0051010//microtubule plus-end binding;GO:0008013//beta-catenin binding","GO:1904781//positive regulation of protein localization to centrosome;GO:0016477//cell migration;GO:0030335//positive regulation of cell migration;GO:0008286//insulin receptor signaling pathway;GO:0030178//negative regulation of Wnt signaling pathway;GO:1904886//beta-catenin destruction complex disassembly;GO:0051260//protein homooligomerization;GO:0007094//mitotic spindle assembly checkpoint;GO:0007050//cell cycle arrest;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0000281//mitotic cytokinesis;GO:0051988//regulation of attachment of spindle microtubules to kinetochore;GO:0016579//protein deubiquitination;GO:0007026//negative regulation of microtubule depolymerization;GO:0006974//cellular response to DNA damage stimulus;GO:0010942//positive regulation of cell death;GO:0008285//negative regulation of cell proliferation;GO:0032886//regulation of microtubule-based process;GO:0031274//positive regulation of pseudopodium assembly;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0007155//cell adhesion;GO:0060070//canonical Wnt signaling pathway;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0070830//bicellular tight junction assembly;GO:0097194//execution phase of apoptosis;GO:0045732//positive regulation of protein catabolic process;GO:0016055//Wnt signaling pathway;GO:0006461//protein complex assembly;GO:1904885//beta-catenin destruction complex assembly","K02085//adenomatosis polyposis coli protein","NP_001341826.1//adenomatous polyposis coli protein isoform d [Homo sapiens];NP_001341831.1//adenomatous polyposis coli protein isoform i [Homo sapiens];XP_016809115.1//PREDICTED: adenomatous polyposis coli protein isoform X4 [Pan troglodytes];NP_001120983.2//adenomatous polyposis coli protein isoform a [Homo sapiens];NP_001341828.1//adenomatous polyposis coli protein isoform f [Homo sapiens];XP_016809114.1//PREDICTED: adenomatous polyposis coli protein isoform X2 [Pan troglodytes];NP_001341832.1//adenomatous polyposis coli protein isoform j [Homo sapiens];NP_001341825.1//adenomatous polyposis coli protein isoform c [Homo sapiens];NP_000029.2//adenomatous polyposis coli protein isoform b [Homo sapiens];XP_016809117.1//PREDICTED: adenomatous polyposis coli protein isoform X7 [Pan troglodytes]","1//3;2//1;5"]
[5602,6718,0.2,0.1,-1,0.203161797849462,"*",0.1088176,"MAPK10","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0043005//neuron projection","GO:0004705//JUN kinase activity;GO:0005524//ATP binding;GO:0004708//MAP kinase kinase activity;GO:0004707//MAP kinase activity","GO:0010468//regulation of gene expression;GO:0007165//signal transduction;GO:0009416//response to light stimulus;GO:0006468//protein phosphorylation;GO:0048511//rhythmic process;GO:0051090//regulation of DNA binding transcription factor activity;GO:0048666//neuron development;GO:0007254//JNK cascade;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0042752//regulation of circadian rhythm","K04440//c-Jun N-terminal kinase [EC:2.7.11.24]","XP_006143356.1//PREDICTED: mitogen-activated protein kinase 10 [Tupaia chinensis];XP_021162857.1//mitogen-activated protein kinase 10 isoform X1 [Fundulus heteroclitus];NP_001304998.1//mitogen-activated protein kinase 10 isoform 1x [Homo sapiens]","4;1//3;3//A2MP1"]
[50650,3629,3.27,1.64,-0.995594820879999,{"v":1.95399877456647e-06,"d":"1.95E-06"},"*",{"v":3.38592e-07,"d":"3.39E-07"},"ARHGEF3","GO:0005829//cytosol;GO:0005622//intracellular","GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005089//Rho guanyl-nucleotide exchange factor activity","GO:0007266//Rho protein signal transduction;GO:0043065//positive regulation of apoptotic process;GO:0035556//intracellular signal transduction;GO:0035023//regulation of Rho protein signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction","K20683//Rho guanine nucleotide exchange factor 3/8","XP_011229573.2//PREDICTED: rho guanine nucleotide exchange factor 3 isoform X1 [Ailuropoda melanoleuca];BAD92898.1//Rho guanine nucleotide exchange factor 3 variant, partial [Homo sapiens];XP_007982868.1//PREDICTED: rho guanine nucleotide exchange factor 3 isoform X1 [Chlorocebus sabaeus];NP_001122087.1//rho guanine nucleotide exchange factor 3 isoform 1 [Homo sapiens]","1//3;2//1"]
[196528,8619,3.98,2,-0.992768430768924,{"v":2.36874985756677e-16,"d":"2.37E-16"},"*",{"v":1.49919e-17,"d":"1.50E-17"},"ARID2","GO:0005654//nucleoplasm;GO:0005886//plasma membrane","GO:0046872//metal ion binding;GO:0003677//DNA binding","GO:0042592//homeostatic process;GO:0060982//coronary artery morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0030336//negative regulation of cell migration;GO:0048568//embryonic organ development;GO:0006337//nucleosome disassembly;GO:0003007//heart morphogenesis;GO:0060038//cardiac muscle cell proliferation;GO:0016569//covalent chromatin modification;GO:0008285//negative regulation of cell proliferation","K11765//AT-rich interactive domain-containing protein 2","NP_001334768.1//AT-rich interactive domain-containing protein 2 isoform 2 [Homo sapiens];NP_689854.2//AT-rich interactive domain-containing protein 2 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[8458,4860,7.72,3.9,-0.98512672351847,{"v":1.49824759181034e-17,"d":"1.50E-17"},"*",{"v":8.70398e-19,"d":"8.70E-19"},"TTF2","GO:0008023//transcription elongation factor complex;GO:0005681//spliceosomal complex;GO:0005829//cytosol","GO:0003677//DNA binding;GO:0005524//ATP binding;GO:0008270//zinc ion binding;GO:0004386//helicase activity;GO:0008094//DNA-dependent ATPase activity","GO:0006397//mRNA processing;GO:0006353//DNA-templated transcription, termination;GO:0006355//regulation of transcription, DNA-templated;GO:0006369//termination of RNA polymerase II transcription;GO:0008380//RNA splicing","K15173//transcription termination factor 2 [EC:3.6.4.-]","NP_003585.3//transcription termination factor 2 [Homo sapiens]","3//A2MP1"]
[9619,2946,0.81,0.41,-0.982297998266541,0.0606091441002737,"*",0.0263358,"ABCG1","GO:0009897//external side of plasma membrane;GO:0000139//Golgi membrane;GO:0005768//endosome;GO:0005887//integral component of plasma membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005739//mitochondrion;GO:0055037//recycling endosome;GO:0005886//plasma membrane","GO:0005524//ATP binding;GO:0015485//cholesterol binding;GO:0046982//protein heterodimerization activity;GO:0017127//cholesterol transporter activity;GO:0042803//protein homodimerization activity;GO:0046983//protein dimerization activity;GO:0005543//phospholipid binding;GO:0043531//ADP binding;GO:0019534//toxin transmembrane transporter activity;GO:0034041//sterol-transporting ATPase activity;GO:0034437//glycoprotein transporter activity;GO:0005548//phospholipid transporter activity","GO:0010875//positive regulation of cholesterol efflux;GO:0034436//glycoprotein transport;GO:0042987//amyloid precursor protein catabolic process;GO:0008203//cholesterol metabolic process;GO:0006355//regulation of transcription, DNA-templated;GO:0009720//detection of hormone stimulus;GO:0034374//low-density lipoprotein particle remodeling;GO:0010872//regulation of cholesterol esterification;GO:0033344//cholesterol efflux;GO:0010033//response to organic substance;GO:0042632//cholesterol homeostasis;GO:0055091//phospholipid homeostasis;GO:0055085//transmembrane transport;GO:0033993//response to lipid;GO:0010887//negative regulation of cholesterol storage;GO:0032367//intracellular cholesterol transport;GO:0010745//negative regulation of macrophage derived foam cell differentiation;GO:0034375//high-density lipoprotein particle remodeling;GO:0033700//phospholipid efflux;GO:0045542//positive regulation of cholesterol biosynthetic process;GO:0043691//reverse cholesterol transport","K05679//ATP-binding cassette, subfamily G (WHITE), member 1","NP_997512.1//ATP-binding cassette sub-family G member 1 isoform 7 [Homo sapiens];NP_997510.1//ATP-binding cassette sub-family G member 1 isoform 5 [Homo sapiens];NP_058198.2//ATP-binding cassette sub-family G member 1 isoform 2 [Homo sapiens];NP_997057.1//ATP-binding cassette sub-family G member 1 isoform 3 [Homo sapiens];NP_004906.3//ATP-binding cassette sub-family G member 1 isoform 4 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[54801,6279,12.33,6.25,-0.98024470485339,{"v":3.74542468248588e-35,"d":"3.75E-35"},"*",{"v":8.30024e-37,"d":"8.30E-37"},"HAUS6","GO:0005815//microtubule organizing center;GO:0005874//microtubule;GO:0070652//HAUS complex;GO:0005829//cytosol;GO:0005819//spindle;GO:0016607//nuclear speck;GO:0005813//centrosome","NA","GO:0010389//regulation of G2/M transition of mitotic cell cycle;GO:0097711//ciliary basal body-plasma membrane docking;GO:0007098//centrosome cycle;GO:0051225//spindle assembly;GO:0051301//cell division;GO:0000086//G2/M transition of mitotic cell cycle","K16589//HAUS augmin-like complex subunit 6","NP_001257819.1//HAUS augmin-like complex subunit 6 isoform 2 [Homo sapiens];NP_060115.3//HAUS augmin-like complex subunit 6 isoform 1 [Homo sapiens]","1//3;4"]
[9754,4962,1.04,0.53,-0.972519263577893,3.88547023774558E-3,"*",0.001225672,"STARD8","GO:0005925//focal adhesion;GO:0005829//cytosol","GO:0008289//lipid binding;GO:0005096//GTPase activator activity","GO:0007165//signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction","K20632//deleted in liver cancer protein","CAH18253.1//hypothetical protein [Homo sapiens];XP_005593880.2//PREDICTED: stAR-related lipid transfer protein 8 isoform X2 [Macaca fascicularis];NP_001135975.1//stAR-related lipid transfer protein 8 isoform a [Homo sapiens]","4;2//1"]
[8705,1704,0.47,0.24,-0.969626350956481,0.347927930807249,"*",0.211536,"B3GALT4","GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0008499//UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity;GO:0047915//ganglioside galactosyltransferase activity;GO:0008378//galactosyltransferase activity","GO:0006486//protein glycosylation;GO:0001574//ganglioside biosynthetic process","K00715//ganglioside galactosyltransferase [EC:2.4.1.62]","NP_003773.1//beta-1,3-galactosyltransferase 4 [Homo sapiens]","3//A2MP1"]
[1591,3134,191.48,97.78,-0.969582400711629,{"v":2.14276917473684e-266,"d":"2.14E-266"},"*",{"v":2.54868e-269,"d":"2.55E-269"},"CYP24A1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005886//plasma membrane","GO:0008403//25-hydroxycholecalciferol-24-hydroxylase activity;GO:0020037//heme binding;GO:0030342//1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity;GO:0005506//iron ion binding;GO:0016491//oxidoreductase activity","GO:0070561//vitamin D receptor signaling pathway;GO:0001649//osteoblast differentiation;GO:0006766//vitamin metabolic process;GO:0042369//vitamin D catabolic process;GO:0042359//vitamin D metabolic process;GO:0033280//response to vitamin D;GO:0055114//oxidation-reduction process","K07436//vitamin D3 24-hydroxylase [EC:1.14.15.16]","XP_009214176.2//1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial [Papio anubis];NP_001122387.1//1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial isoform 2 precursor [Homo sapiens]","4;1//3"]
[23683,5915,5.62,2.88,-0.964501318778614,{"v":4.67248812197309e-15,"d":"4.67E-15"},"*",{"v":3.26144e-16,"d":"3.26E-16"},"PRKD3","GO:0016020//membrane;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0004697//protein kinase C activity","GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0089700//protein kinase D signaling;GO:0030148//sphingolipid biosynthetic process;GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction","K06070//protein kinase D [EC:2.7.11.13]","NP_005804.1//serine/threonine-protein kinase D3 [Homo sapiens]",4]
[5016,2258,0.35,0.18,-0.959358015502654,0.347963759036145,"*",0.211536,"OVGP1","GO:0035805//egg coat;GO:0030133//transport vesicle;GO:0005829//cytosol;GO:0098595//perivitelline space;GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0008061//chitin binding;GO:0004568//chitinase activity","GO:0007565//female pregnancy;GO:0006032//chitin catabolic process;GO:2000360//negative regulation of binding of sperm to zona pellucida;GO:0005975//carbohydrate metabolic process;GO:0007339//binding of sperm to zona pellucida","K17526//oviduct-specific glycoprotein","NP_002548.3//oviduct-specific glycoprotein precursor [Homo sapiens]","3//A2MP1"]
[146227,2824,1.38,0.71,-0.958777337273487,0.0112326043333928,"*",0.00393992,"BEAN1","GO:0016021//integral component of membrane","NA","NA","K17595//spermatogenesis-associated protein 2;K19324//protein BEAN1","XP_017715720.1//PREDICTED: protein BEAN1 isoform X1 [Rhinopithecus bieti];NP_001171491.1//protein BEAN1 isoform 1 [Homo sapiens];XP_016785459.1//PREDICTED: protein BEAN1 isoform X2 [Pan troglodytes]","4;3//A2MP1;2//1"]
[253461,8295,11.38,5.87,-0.95506814919653,{"v":3.15559205581395e-40,"d":"3.16E-40"},"*",{"v":5.94612e-42,"d":"5.95E-42"},"ZBTB38","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0072562//blood microparticle;GO:0005694//chromosome","GO:0046872//metal ion binding;GO:0003700//DNA binding transcription factor activity;GO:0042803//protein homodimerization activity;GO:0008327//methyl-CpG binding;GO:0003676//nucleic acid binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006275//regulation of DNA replication;GO:0006351//transcription, DNA-templated;GO:0006974//cellular response to DNA damage stimulus","K10510//zinc finger and BTB domain-containing protein 38","XP_011813485.1//PREDICTED: zinc finger and BTB domain-containing protein 38 isoform X1 [Colobus angolensis palliatus];XP_011510909.1//PREDICTED: zinc finger and BTB domain-containing protein 38 isoform X1 [Homo sapiens]","1//3;2//1"]
[23767,3830,1.8,0.93,-0.952694285221643,0.000909519850214302,"*",0.000252404,"FLRT3","GO:0005615//extracellular space;GO:0044295//axonal growth cone;GO:0005925//focal adhesion;GO:0005737//cytoplasm;GO:0097060//synaptic membrane;GO:0005578//proteinaceous extracellular matrix;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0016021//integral component of membrane;GO:0043679//axon terminus;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane","GO:0005057//signal transducer activity, downstream of receptor;GO:0004860//protein kinase inhibitor activity;GO:0030674//protein binding, bridging;GO:0045499//chemorepellent activity;GO:0042803//protein homodimerization activity;GO:0005104//fibroblast growth factor receptor binding","GO:0048678//response to axon injury;GO:0007507//heart development;GO:0046426//negative regulation of JAK-STAT cascade;GO:0003345//proepicardium cell migration involved in pericardium morphogenesis;GO:0051965//positive regulation of synapse assembly;GO:0007416//synapse assembly;GO:0006469//negative regulation of protein kinase activity;GO:1990138//neuron projection extension;GO:0060322//head development;GO:0098742//cell-cell adhesion via plasma-membrane adhesion molecules;GO:0031175//neuron projection development;GO:0019221//cytokine-mediated signaling pathway;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0007411//axon guidance;GO:0048598//embryonic morphogenesis","K16362//leucine-rich repeat transmembrane protein FLRT","NP_037413.1//leucine-rich repeat transmembrane protein FLRT3 precursor [Homo sapiens]","3//A2MP1;2//1"]
[117583,7871,0.56,0.29,-0.949373926930032,0.011032446104245,"*",0.0038559,"PARD3B","GO:0016020//membrane;GO:0012505//endomembrane system;GO:0043234//protein complex;GO:0030054//cell junction;GO:0005923//bicellular tight junction","NA","GO:0051301//cell division;GO:0007049//cell cycle","K04237//partitioning defective protein 3","NP_689739.4//partitioning defective 3 homolog B isoform Par3Lb [Homo sapiens];NP_995585.2//partitioning defective 3 homolog B isoform 4 [Homo sapiens];NP_476518.4//partitioning defective 3 homolog B isoform Par3Lc [Homo sapiens];NP_001289698.1//partitioning defective 3 homolog B isoform Par3La [Homo sapiens]","6;1//3;3//A2MP1;5"]
[170691,6358,0.25,0.13,-0.943416471633632,0.188734445401823,"*",0.0998258,"ADAMTS17","GO:0005578//proteinaceous extracellular matrix","GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding;GO:0003676//nucleic acid binding","NA","K08631//a disintegrin and metalloproteinase with thrombospondin motifs 17 [EC:3.4.24.-]","NP_620688.2//A disintegrin and metalloproteinase with thrombospondin motifs 17 preproprotein [Homo sapiens]","3//A2MP1"]
[2033,8761,10.11,5.26,-0.942648292610712,{"v":1.49527453169231e-37,"d":"1.50E-37"},"*",{"v":3.04222e-39,"d":"3.04E-39"},"EP300","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription factor complex;GO:0005829//cytosol;GO:0000123//histone acetyltransferase complex;GO:0005694//chromosome","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0140068//histone crotonyltransferase activity;GO:0097157//pre-mRNA intronic binding;GO:0031490//chromatin DNA binding;GO:0061920//protein propionyltransferase activity;GO:0004468//lysine N-acetyltransferase activity, acting on acetyl phosphate as donor;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0050681//androgen receptor binding;GO:0003712//transcription cofactor activity;GO:0008270//zinc ion binding;GO:0001102//RNA polymerase II activating transcription factor binding;GO:0016407//acetyltransferase activity;GO:0033613//activating transcription factor binding;GO:0097677//STAT family protein binding;GO:0004402//histone acetyltransferase activity;GO:0002039//p53 binding;GO:0140069//histone butyryltransferase activity;GO:0003713//transcription coactivator activity;GO:0003684//damaged DNA binding;GO:0008022//protein C-terminus binding;GO:0008013//beta-catenin binding","GO:0043969//histone H2B acetylation;GO:0140066//peptidyl-lysine crotonylation;GO:0043627//response to estrogen;GO:0090043//regulation of tubulin deacetylation;GO:0032092//positive regulation of protein binding;GO:0043923//positive regulation by host of viral transcription;GO:0140067//peptidyl-lysine butyrylation;GO:0034644//cellular response to UV;GO:0001756//somitogenesis;GO:0007507//heart development;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0001666//response to hypoxia;GO:0006915//apoptotic process;GO:1904837//beta-catenin-TCF complex assembly;GO:0010742//macrophage derived foam cell differentiation;GO:0007519//skeletal muscle tissue development;GO:0030324//lung development;GO:0045815//positive regulation of gene expression, epigenetic;GO:0006355//regulation of transcription, DNA-templated;GO:0018076//N-terminal peptidyl-lysine acetylation;GO:0060765//regulation of androgen receptor signaling pathway;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0043967//histone H4 acetylation;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0030220//platelet formation;GO:0030183//B cell differentiation;GO:0031648//protein destabilization;GO:0007623//circadian rhythm;GO:0035855//megakaryocyte development;GO:0006990//positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response;GO:0009887//animal organ morphogenesis;GO:0045444//fat cell differentiation;GO:0061921//peptidyl-lysine propionylation;GO:0050821//protein stabilization","K04498//E1A/CREB-binding protein [EC:2.3.1.48]","NP_001420.2//histone acetyltransferase p300 [Homo sapiens]","3//A2MP1"]
[440672,3650,5.46,2.85,-0.937939031867748,{"v":5.79397588985212e-09,"d":"5.79E-09"},"*",{"v":7.1128e-10,"d":"7.11E-10"},"NUDT4B","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005737//cytoplasm","GO:0052841//inositol bisdiphosphate tetrakisphosphate diphosphatase activity;GO:0050072//m7G(5')pppN diphosphatase activity;GO:0052844//inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity;GO:0034431//bis(5'-adenosyl)-hexaphosphatase activity;GO:0016787//hydrolase activity;GO:0008486//diphosphoinositol-polyphosphate diphosphatase activity;GO:0052842//inositol diphosphate pentakisphosphate diphosphatase activity;GO:0052843//inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity;GO:0030515//snoRNA binding;GO:0052845//inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity;GO:0052848//inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity;GO:0052846//inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity;GO:0046872//metal ion binding;GO:0000298//endopolyphosphatase activity;GO:0034432//bis(5'-adenosyl)-pentaphosphatase activity;GO:0052847//inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity;GO:0052840//inositol diphosphate tetrakisphosphate diphosphatase activity","GO:0019935//cyclic-nucleotide-mediated signaling;GO:0046907//intracellular transport;GO:0071543//diphosphoinositol polyphosphate metabolic process;GO:0009187//cyclic nucleotide metabolic process;GO:1901907//diadenosine pentaphosphate catabolic process;GO:0019722//calcium-mediated signaling;GO:0035556//intracellular signal transduction;GO:0046831//regulation of RNA export from nucleus;GO:1901911//adenosine 5'-(hexahydrogen pentaphosphate) catabolic process;GO:1901909//diadenosine hexaphosphate catabolic process;GO:0043647//inositol phosphate metabolic process","K07766//diphosphoinositol-polyphosphate diphosphatase [EC:3.6.1.52]","XP_011743007.1//PREDICTED: LOW QUALITY PROTEIN: diphosphoinositol polyphosphate phosphohydrolase 2 [Macaca nemestrina]","1//3"]
[11107,5170,0.44,0.23,-0.935869662580284,0.0606178774063401,"*",0.0263358,"PRDM5","NA","GO:0046872//metal ion binding;GO:0000976//transcription regulatory region sequence-specific DNA binding","NA","K09228//KRAB domain-containing zinc finger protein","NP_001179836.2//PR domain zinc finger protein 5 [Bos taurus];XP_003221822.2//PREDICTED: PR domain zinc finger protein 5 isoform X2 [Anolis carolinensis];XP_006866344.1//PREDICTED: PR domain zinc finger protein 5-like isoform X3 [Chrysochloris asiatica]","1//3;3//A2MP1"]
[388335,2698,2.12,1.11,-0.933504588213093,2.46466970244509E-3,"*",0.000744616,"TMEM220","NA","NA","NA","K07560//D-tyrosyl-tRNA(Tyr) deacylase [EC:3.1.-.-];K17985//activating molecule in BECN1-regulated autophagy protein 1;K04613//vomeronasal 2 receptor;K01064//wingless-type MMTV integration site family, member 9","XP_011828567.1//PREDICTED: transmembrane protein 220 isoform X3 [Mandrillus leucophaeus];XP_011828566.1//PREDICTED: transmembrane protein 220 isoform X2 [Mandrillus leucophaeus];XP_016880106.1//PREDICTED: transmembrane protein 220 isoform X2 [Homo sapiens];XP_011828568.1//PREDICTED: transmembrane protein 220 isoform X4 [Mandrillus leucophaeus]","1//3;2//1"]
[55284,8426,3.47,1.82,-0.930997212379565,0.0273391738216868,"*",0.01065396,"UBE2W","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm","GO:0061630//ubiquitin protein ligase activity;GO:0005524//ATP binding;GO:0031625//ubiquitin protein ligase binding;GO:0004842//ubiquitin-protein transferase activity","GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0006281//DNA repair;GO:0006513//protein monoubiquitination;GO:0016567//protein ubiquitination;GO:0006515//protein quality control for misfolded or incompletely synthesized proteins;GO:0070979//protein K11-linked ubiquitination;GO:0071218//cellular response to misfolded protein","K10688//ubiquitin-conjugating enzyme E2 W [EC:2.3.2.25]","NP_001257944.1//ubiquitin-conjugating enzyme E2 W isoform 3 [Homo sapiens];NP_060769.4//ubiquitin-conjugating enzyme E2 W isoform 2 [Homo sapiens];NP_001001481.2//ubiquitin-conjugating enzyme E2 W isoform 1 [Homo sapiens]","4;1//3;2//1"]
[6653,10973,0.38,0.2,-0.925999418556223,0.0153838050569162,"*",5.58378E-3,"SORL1","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0010008//endosome membrane;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0034362//low-density lipoprotein particle;GO:0005802//trans-Golgi network;GO:0000139//Golgi membrane;GO:0005768//endosome;GO:0005887//integral component of plasma membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0031985//Golgi cisterna;GO:0055037//recycling endosome;GO:0005641//nuclear envelope lumen;GO:0005769//early endosome","GO:0005041//low-density lipoprotein receptor activity;GO:0001540//amyloid-beta binding;GO:0030169//low-density lipoprotein particle binding;GO:0030306//ADP-ribosylation factor binding;GO:0004888//transmembrane signaling receptor activity","GO:1902955//positive regulation of early endosome to recycling endosome transport;GO:1901215//negative regulation of neuron death;GO:1902430//negative regulation of amyloid-beta formation;GO:1902771//positive regulation of choline O-acetyltransferase activity;GO:0008203//cholesterol metabolic process;GO:1902966//positive regulation of protein localization to early endosome;GO:1902948//negative regulation of tau-protein kinase activity;GO:0043407//negative regulation of MAP kinase activity;GO:0006869//lipid transport;GO:0032460//negative regulation of protein oligomerization;GO:0044267//cellular protein metabolic process;GO:0045053//protein retention in Golgi apparatus;GO:0032091//negative regulation of protein binding;GO:1902997//negative regulation of neurofibrillary tangle assembly;GO:0006810//transport;GO:0006605//protein targeting;GO:0050768//negative regulation of neurogenesis;GO:0006622//protein targeting to lysosome;GO:1902953//positive regulation of ER to Golgi vesicle-mediated transport;GO:2001137//positive regulation of endocytic recycling;GO:0070863//positive regulation of protein exit from endoplasmic reticulum;GO:1902960//negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process;GO:0006898//receptor-mediated endocytosis;GO:0045732//positive regulation of protein catabolic process;GO:0000042//protein targeting to Golgi;GO:0051604//protein maturation;GO:0006892//post-Golgi vesicle-mediated transport;GO:1902963//negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process;GO:0014910//regulation of smooth muscle cell migration","K04550//low-density lipoprotein receptor-related protein 1 (alpha-2-macroglobulin receptor)","NP_003096.1//sortilin-related receptor preproprotein [Homo sapiens]",5]
[148014,859,0.19,0.1,-0.925999418556223,0.729690549511448,"*",0.626454,"TTC9B","NA","NA","NA","K09572//FK506-binding protein 6 [EC:5.2.1.8];K05864//peptidyl-prolyl isomerase D [EC:5.2.1.8];K20097//FK506-binding protein-like","NP_689692.2//tetratricopeptide repeat protein 9B [Homo sapiens]",5]
[51655,1740,0.53,0.28,-0.920565532505595,0.289269245515165,"*",0.1683752,"RASD1","GO:0016020//membrane;GO:0016529//sarcoplasmic reticulum","GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0007165//signal transduction","K07843//RAS, dexamethasone-induced Ras-related protein 1","XP_020035893.1//dexamethasone-induced Ras-related protein 1 [Castor canadensis];XP_006042902.1//PREDICTED: glutenin, high molecular weight subunit DX5 isoform X1 [Bubalus bubalis]","4;1//3"]
[342908,1868,0.17,0.09,-0.917537839808027,0.610799981836529,"*",0.454716,"ZNF404","GO:0005634//nucleus;GO:0005622//intracellular","GO:0046872//metal ion binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","XP_004401072.1//PREDICTED: zinc finger protein 404 [Odobenus rosmarus divergens]","2//1"]
[6884,577,4.75,2.52,-0.914503779718394,0.0746664907360761,"*",0.0334022,"TAF13","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005669//transcription factor TFIID complex","GO:0003743//translation initiation factor activity;GO:0003677//DNA binding;GO:0008022//protein C-terminus binding;GO:0003712//transcription cofactor activity;GO:0046982//protein heterodimerization activity;GO:0003700//DNA binding transcription factor activity","GO:0006368//transcription elongation from RNA polymerase II promoter;GO:1901796//regulation of signal transduction by p53 class mediator;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0042795//snRNA transcription from RNA polymerase II promoter;GO:0006355//regulation of transcription, DNA-templated;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006352//DNA-templated transcription, initiation;GO:0006366//transcription from RNA polymerase II promoter","K03127//transcription initiation factor TFIID subunit 13","XP_020734151.1//transcription initiation factor TFIID subunit 13 [Odocoileus virginianus texanus]","3//A2MP1"]
[140735,1522,28.71,15.26,-0.911798368372651,{"v":1.72340757894737E-17,"d":"1.72E-17"},"*",{"v":1.00444e-18,"d":"1.00E-18"},"DYNLL2","NA","NA","NA","K10418//dynein light chain LC8-type","EAW94483.1//dynein, light chain, LC8-type 2, isoform CRA_a, partial [Homo sapiens]","2//1"]
[90075,2601,2.42,1.29,-0.90763598185134,0.00254056224333815,"*",0.00076993,"ZNF30","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","NP_001092907.1//zinc finger protein 30 isoform a [Homo sapiens];NP_919306.2//zinc finger protein 30 isoform b [Homo sapiens]","1//3;2//1"]
[1188,2174,0.15,0.08,-0.906890595608519,0.436583569989645,"*",0.290336,"CLCNKB","GO:0005887//integral component of plasma membrane;GO:0034707//chloride channel complex;GO:0005886//plasma membrane","GO:0046872//metal ion binding;GO:0005247//voltage-gated chloride channel activity","GO:0006810//transport;GO:0034220//ion transmembrane transport;GO:0007588//excretion;GO:1902476//chloride transmembrane transport","K05017//chloride channel Ka;K05018//chloride channel Kb","XP_016810262.1//PREDICTED: chloride channel protein ClC-Kb isoform X1 [Pan troglodytes];NP_001159417.2//chloride channel protein ClC-Kb isoform 2 [Homo sapiens]","4;2//1"]
[8671,7693,0.75,0.4,-0.906890595608519,0.00416746708965517,"*",1.32402E-3,"SLC4A4","GO:0070062//extracellular exosome;GO:0016323//basolateral plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0008510//sodium:bicarbonate symporter activity;GO:0005452//inorganic anion exchanger activity;GO:0042802//identical protein binding","GO:0006810//transport;GO:0015701//bicarbonate transport;GO:0051453//regulation of intracellular pH;GO:0006814//sodium ion transport","K13575//solute carrier family 4 (sodium bicarbonate cotransporter), member 4","XP_018881269.1//PREDICTED: electrogenic sodium bicarbonate cotransporter 1 isoform X1 [Gorilla gorilla gorilla];NP_003750.1//electrogenic sodium bicarbonate cotransporter 1 isoform 2 [Homo sapiens];NP_001128214.1//electrogenic sodium bicarbonate cotransporter 1 isoform 3 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[4488,2224,5.26,2.81,-0.904492669071376,{"v":2.53777993275293e-05,"d":"2.54E-05"},"*",{"v":5.29194e-06,"d":"5.29E-06"},"MSX2","GO:0005634//nucleus;GO:0005829//cytosol;GO:0016607//nuclear speck","GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003712//transcription cofactor activity;GO:0044212//transcription regulatory region DNA binding;GO:0008134//transcription factor binding;GO:0001227//transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding","GO:0003148//outflow tract septum morphogenesis;GO:0001649//osteoblast differentiation;GO:0060364//frontal suture morphogenesis;GO:0090427//activation of meiosis;GO:0030513//positive regulation of BMP signaling pathway;GO:0070166//enamel mineralization;GO:0060444//branching involved in mammary gland duct morphogenesis;GO:0035880//embryonic nail plate morphogenesis;GO:0061312//BMP signaling pathway involved in heart development;GO:0045617//negative regulation of keratinocyte differentiation;GO:0008285//negative regulation of cell proliferation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0032792//negative regulation of CREB transcription factor activity;GO:0035116//embryonic hindlimb morphogenesis;GO:0045599//negative regulation of fat cell differentiation;GO:0043066//negative regulation of apoptotic process;GO:0060363//cranial suture morphogenesis;GO:0007275//multicellular organism development;GO:0009952//anterior/posterior pattern specification;GO:2000678//negative regulation of transcription regulatory region DNA binding;GO:0003198//epithelial to mesenchymal transition involved in endocardial cushion formation;GO:0006355//regulation of transcription, DNA-templated;GO:0002063//chondrocyte development;GO:0023019//signal transduction involved in regulation of gene expression;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0060346//bone trabecula formation;GO:0003416//endochondral bone growth;GO:2001055//positive regulation of mesenchymal cell apoptotic process;GO:0006351//transcription, DNA-templated;GO:0045669//positive regulation of osteoblast differentiation;GO:0035115//embryonic forelimb morphogenesis;GO:0048863//stem cell differentiation;GO:0035313//wound healing, spreading of epidermal cells;GO:0051795//positive regulation of timing of catagen;GO:0071392//cellular response to estradiol stimulus;GO:0002076//osteoblast development","K09341//homeobox protein MSX","NP_002440.2//homeobox protein MSX-2 [Homo sapiens]",4]
[79983,3949,1.83,0.98,-0.900989994168835,1.34060975731122E-3,"*",0.000384542,"POF1B","GO:0005884//actin filament;GO:0005923//bicellular tight junction;GO:0005912//adherens junction;GO:0030057//desmosome","GO:0051015//actin filament binding","GO:0007015//actin filament organization;GO:0070830//bicellular tight junction assembly;GO:0030036//actin cytoskeleton organization;GO:0003382//epithelial cell morphogenesis","K17388//Rho-associated protein kinase 2 [EC:2.7.11.1]","XP_007990383.1//PREDICTED: protein POF1B isoform X2 [Chlorocebus sabaeus];XP_007990382.1//PREDICTED: protein POF1B isoform X1 [Chlorocebus sabaeus]","1//3;3//A2MP1"]
[84254,3488,15.27,8.19,-0.898764705155843,{"v":6.31495141828255e-21,"d":"6.31E-21"},"*",{"v":2.85426e-22,"d":"2.85E-22"},"CAMKK1","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0004683//calmodulin-dependent protein kinase activity;GO:0005516//calmodulin binding","GO:0018107//peptidyl-threonine phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0045860//positive regulation of protein kinase activity;GO:0035556//intracellular signal transduction","K00908//calcium/calmodulin-dependent protein kinase kinase 1 [EC:2.7.11.17]","XP_011522333.2//PREDICTED: calcium/calmodulin-dependent protein kinase kinase 1 isoform X1 [Homo sapiens];NP_757343.2//calcium/calmodulin-dependent protein kinase kinase 1 isoform c [Homo sapiens]","1//3;2//1"]
[1836,8082,4.86,2.61,-0.896906507035897,{"v":7.77347528312679e-16,"d":"7.77E-16"},"*",{"v":5.10478E-17,"d":"5.10E-17"},"SLC26A2","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005887//integral component of plasma membrane;GO:0016324//apical plasma membrane;GO:0031528//microvillus membrane;GO:0005886//plasma membrane","GO:0019531//oxalate transmembrane transporter activity;GO:0015301//anion:anion antiporter activity;GO:0015116//sulfate transmembrane transporter activity;GO:0005254//chloride channel activity;GO:0008271//secondary active sulfate transmembrane transporter activity;GO:0015106//bicarbonate transmembrane transporter activity","GO:0051453//regulation of intracellular pH;GO:0001503//ossification;GO:0006811//ion transport;GO:0015701//bicarbonate transport;GO:0050428//3'-phosphoadenosine 5'-phosphosulfate biosynthetic process;GO:1902358//sulfate transmembrane transport;GO:1902476//chloride transmembrane transport;GO:0042391//regulation of membrane potential","K14701//solute carrier family 26 (sulfate anion transporter), member 2","XP_016809512.1//PREDICTED: sulfate transporter isoform X1 [Pan troglodytes]","3//A2MP1"]
[342371,7886,6.77,3.64,-0.8952173833763,{"v":4.58780489703808e-21,"d":"4.59E-21"},"*",{"v":2.03628E-22,"d":"2.04E-22"},"ATXN1L","GO:0030425//dendrite;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus","GO:0003723//RNA binding;GO:0003677//DNA binding","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:1902035//positive regulation of hematopoietic stem cell proliferation;GO:0030198//extracellular matrix organization;GO:0006351//transcription, DNA-templated;GO:0048286//lung alveolus development","K21644//HMG box transcription factor 1;K14718//solute carrier family 39 (zinc transporter), member 12","NP_001131147.1//ataxin-1-like [Homo sapiens]","3//A2MP1"]
[9712,4676,4.68,2.52,-0.893084796083488,{"v":4.81837069551778E-9,"d":"4.82E-09"},"*",{"v":5.8548e-10,"d":"5.85E-10"},"USP6NL","GO:0012505//endomembrane system;GO:0032588//trans-Golgi network membrane;GO:0005829//cytosol;GO:0031410//cytoplasmic vesicle;GO:0005886//plasma membrane","GO:0017137//Rab GTPase binding;GO:0005096//GTPase activator activity","GO:0035526//retrograde transport, plasma membrane to Golgi;GO:1903358//regulation of Golgi organization;GO:0090630//activation of GTPase activity;GO:0019068//virion assembly;GO:0043547//positive regulation of GTPase activity;GO:0007030//Golgi organization;GO:0006886//intracellular protein transport;GO:0031338//regulation of vesicle fusion;GO:0048227//plasma membrane to endosome transport","K20133//USP6 N-terminal-like protein","NP_055503.1//USP6 N-terminal-like protein isoform 1 [Homo sapiens];NP_001073960.1//USP6 N-terminal-like protein isoform 2 [Homo sapiens]","3//A2MP1"]
[677,3217,140.18,75.56,-0.891585922544806,{"v":1.05404439E-170,"d":"1.05E-170"},"*",{"v":2.6394e-173,"d":"2.64E-173"},"ZFP36L1","GO:0005634//nucleus;GO:0030529//intracellular ribonucleoprotein complex;GO:0005829//cytosol;GO:0000932//P-body;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0071889//14-3-3 protein binding;GO:0035925//mRNA 3'-UTR AU-rich region binding;GO:0003700//DNA binding transcription factor activity","GO:0072091//regulation of stem cell proliferation;GO:0038066//p38MAPK cascade;GO:0010837//regulation of keratinocyte proliferation;GO:0043491//protein kinase B signaling;GO:0071356//cellular response to tumor necrosis factor;GO:1900153//positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0070371//ERK1 and ERK2 cascade;GO:0051028//mRNA transport;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:1902172//regulation of keratinocyte apoptotic process;GO:0060712//spongiotrophoblast layer development;GO:0021915//neural tube development;GO:0001570//vasculogenesis;GO:0031086//nuclear-transcribed mRNA catabolic process, deadenylation-independent decay;GO:0045647//negative regulation of erythrocyte differentiation;GO:0097403//cellular response to raffinose;GO:0009611//response to wounding;GO:0045577//regulation of B cell differentiation;GO:0007507//heart development;GO:0045600//positive regulation of fat cell differentiation;GO:0045661//regulation of myoblast differentiation;GO:1901991//negative regulation of mitotic cell cycle phase transition;GO:0031440//regulation of mRNA 3'-end processing;GO:0035264//multicellular organism growth;GO:0006915//apoptotic process;GO:0071375//cellular response to peptide hormone stimulus;GO:1904582//positive regulation of intracellular mRNA localization;GO:0071472//cellular response to salt stress;GO:0071456//cellular response to hypoxia;GO:0010468//regulation of gene expression;GO:0048382//mesendoderm development;GO:0071385//cellular response to glucocorticoid stimulus;GO:0033077//T cell differentiation in thymus;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0071320//cellular response to cAMP;GO:0060710//chorio-allantoic fusion;GO:0008283//cell proliferation;GO:0043488//regulation of mRNA stability;GO:0006397//mRNA processing;GO:0000165//MAPK cascade;GO:1904628//cellular response to phorbol 13-acetate 12-myristate;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0032869//cellular response to insulin stimulus;GO:0061158//3'-UTR-mediated mRNA destabilization;GO:0045616//regulation of keratinocyte differentiation;GO:0003342//proepicardium development;GO:0045657//positive regulation of monocyte differentiation","K18753//butyrate response factor","NP_001231630.1//mRNA decay activator protein ZFP36L1 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[285331,3180,2.37,1.28,-0.888743248898259,0.000965021746858169,"*",0.000269196,"CCDC66","NA","NA","NA","K16771//centrosome and spindle pole-associated protein 1;K18730//PERQ amino acid-rich with GYF domain-containing protein;K18626//trichohyalin","NP_001340076.1//coiled-coil domain-containing protein 66 isoform 3 [Homo sapiens];NP_001340083.1//coiled-coil domain-containing protein 66 isoform 8 [Homo sapiens];NP_001340084.1//coiled-coil domain-containing protein 66 isoform 9 [Homo sapiens];NP_001340078.1//coiled-coil domain-containing protein 66 isoform 5 [Homo sapiens];NP_001135419.1//coiled-coil domain-containing protein 66 isoform 1 [Homo sapiens];NP_001340077.1//coiled-coil domain-containing protein 66 isoform 4 [Homo sapiens];XP_016796836.1//PREDICTED: coiled-coil domain-containing protein 66 isoform X5 [Pan troglodytes];NP_001340080.1//coiled-coil domain-containing protein 66 isoform 7 [Homo sapiens];NP_001340079.1//coiled-coil domain-containing protein 66 isoform 6 [Homo sapiens];NP_001012524.4//coiled-coil domain-containing protein 66 isoform 2 [Homo sapiens]","1//3;2//1;5"]
[22866,5717,1.35,0.73,-0.886991038170814,0.00115475456201636,"*",0.000326966,"CNKSR2","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0014069//postsynaptic density;GO:0005737//cytoplasm;GO:0045211//postsynaptic membrane;GO:0043025//neuronal cell body;GO:0043005//neuron projection","GO:0016301//kinase activity;GO:0042802//identical protein binding","GO:0009966//regulation of signal transduction","K17536//connector enhancer of kinase suppressor of Ras 2","XP_016884847.1//PREDICTED: connector enhancer of kinase suppressor of ras 2 isoform X3 [Homo sapiens];NP_055742.2//connector enhancer of kinase suppressor of ras 2 isoform 1 [Homo sapiens];NP_001317699.1//connector enhancer of kinase suppressor of ras 2 isoform 5 [Homo sapiens];NP_001317701.1//connector enhancer of kinase suppressor of ras 2 isoform 7 [Homo sapiens];XP_011543773.1//PREDICTED: connector enhancer of kinase suppressor of ras 2 isoform X1 [Homo sapiens];NP_001162118.1//connector enhancer of kinase suppressor of ras 2 isoform 2 [Homo sapiens];XP_011543774.1//PREDICTED: connector enhancer of kinase suppressor of ras 2 isoform X2 [Homo sapiens]","1//3;4;2//1"]
[126393,1480,1.31,0.71,-0.883675882032768,0.146536121980886,"*",0.0739102,"HSPB6","GO:0005634//nucleus;GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0005212//structural constituent of eye lens;GO:0051082//unfolded protein binding;GO:0051087//chaperone binding;GO:0042803//protein homodimerization activity","GO:0006937//regulation of muscle contraction;GO:0010667//negative regulation of cardiac muscle cell apoptotic process;GO:0045766//positive regulation of angiogenesis;GO:0061077//chaperone-mediated protein folding","K09545//heat shock protein beta-6","XP_018871137.1//PREDICTED: heat shock protein beta-6 [Gorilla gorilla gorilla]","2//1"]
[102,5030,20.91,11.35,-0.881500764411302,{"v":3.81031677793103e-41,"d":"3.81E-41"},"*",{"v":6.91744e-43,"d":"6.92E-43"},"ADAM10","GO:0016020//membrane;GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0097038//perinuclear endoplasmic reticulum;GO:0097197//tetraspanin-enriched microdomain;GO:0005737//cytoplasm;GO:0000139//Golgi membrane;GO:0005798//Golgi-associated vesicle;GO:0016021//integral component of membrane;GO:0070821//tertiary granule membrane;GO:0005886//plasma membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005925//focal adhesion;GO:0014069//postsynaptic density;GO:0009986//cell surface;GO:0005794//Golgi apparatus;GO:0035579//specific granule membrane","GO:0004175//endopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0005102//receptor binding;GO:0042803//protein homodimerization activity;GO:0019901//protein kinase binding;GO:0046872//metal ion binding;GO:0005178//integrin binding;GO:0008237//metallopeptidase activity;GO:0017124//SH3 domain binding","GO:0043687//post-translational protein modification;GO:0010820//positive regulation of T cell chemotaxis;GO:0006509//membrane protein ectodomain proteolysis;GO:0051089//constitutive protein ectodomain proteolysis;GO:0030335//positive regulation of cell migration;GO:0007162//negative regulation of cell adhesion;GO:0030307//positive regulation of cell growth;GO:0044267//cellular protein metabolic process;GO:0016485//protein processing;GO:0043312//neutrophil degranulation;GO:0007229//integrin-mediated signaling pathway;GO:0006468//protein phosphorylation;GO:0007267//cell-cell signaling;GO:0048013//ephrin receptor signaling pathway;GO:0001701//in utero embryonic development;GO:0022617//extracellular matrix disassembly;GO:0034612//response to tumor necrosis factor;GO:0007220//Notch receptor processing;GO:0007219//Notch signaling pathway;GO:0051088//PMA-inducible membrane protein ectodomain proteolysis;GO:0042117//monocyte activation;GO:0008284//positive regulation of cell proliferation","K06704//disintegrin and metalloproteinase domain-containing protein 10 [EC:3.4.24.81]","NP_001307499.1//disintegrin and metalloproteinase domain-containing protein 10 isoform 2 precursor [Homo sapiens];NP_001101.1//disintegrin and metalloproteinase domain-containing protein 10 isoform 1 preproprotein [Homo sapiens]","1//3;3//A2MP1"]
[11215,9926,2.48,1.35,-0.877380713336044,{"v":4.37920457142857e-10,"d":"4.38E-10"},"*",{"v":4.7016e-11,"d":"4.70E-11"},"AKAP11","GO:0005815//microtubule organizing center;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005777//peroxisome;GO:0005886//plasma membrane","GO:0051018//protein kinase A binding;GO:0016301//kinase activity;GO:0008157//protein phosphatase 1 binding","GO:0010738//regulation of protein kinase A signaling;GO:0035556//intracellular signal transduction","K16527//A-kinase anchor protein 11","NP_057332.1//A-kinase anchor protein 11 [Homo sapiens]","3//A2MP1"]
[29104,995,4.4,2.4,-0.874469117916141,0.0168875156775183,"*",0.00620252,"N6AMT1","GO:0043234//protein complex;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0008757//S-adenosylmethionine-dependent methyltransferase activity;GO:0008168//methyltransferase activity;GO:0008276//protein methyltransferase activity;GO:0003676//nucleic acid binding","GO:0006415//translational termination;GO:0030307//positive regulation of cell growth;GO:0032259//methylation","K19589//release factor glutamine methyltransferase [EC:2.1.1.297]","NP_037372.4//hemK methyltransferase family member 2 isoform 1 [Homo sapiens];NP_877426.4//hemK methyltransferase family member 2 isoform 2 [Homo sapiens]","4;5"]
[154881,5051,3.06,1.67,-0.8736835502186,{"v":1.59612348533724E-6,"d":"1.60E-06"},"*",{"v":2.72582e-07,"d":"2.73E-07"},"KCTD7","GO:0005829//cytosol;GO:0005886//plasma membrane","NA","GO:0043687//post-translational protein modification;GO:0051260//protein homooligomerization","K21917//BTB/POZ domain-containing protein KCTD7/14","NP_694578.1//BTB/POZ domain-containing protein KCTD7 isoform 1 [Homo sapiens];XP_011787657.1//PREDICTED: BTB/POZ domain-containing protein KCTD7 isoform X1 [Colobus angolensis palliatus]","4;2//1"]
[3221,1867,9.5,5.2,-0.869415890189856,{"v":3.10115430806846e-06,"d":"3.10E-06"},"*",{"v":5.55816e-07,"d":"5.56E-07"},"HOXC4","GO:0005634//nucleus","GO:0071837//HMG box domain binding;GO:0001205//transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0009952//anterior/posterior pattern specification;GO:0007275//multicellular organism development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0048562//embryonic organ morphogenesis;GO:0051216//cartilage development","K09304//homeobox protein HoxA/B/C/D4","XP_017801399.2//homeobox protein Hox-C4 isoform X1 [Papio anubis];XP_016778776.1//PREDICTED: homeobox protein Hox-C4 isoform X1 [Pan troglodytes]","2//1;5"]
[1789,4224,4.52,2.48,-0.865982652028312,{"v":5.14613203243243e-08,"d":"5.15E-08"},"*",{"v":7.15188e-09,"d":"7.15E-09"},"DNMT3B","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0042826//histone deacetylase binding;GO:0003682//chromatin binding;GO:0003886//DNA (cytosine-5-)-methyltransferase activity;GO:0009008//DNA-methyltransferase activity","GO:0010468//regulation of gene expression;GO:0045666//positive regulation of neuron differentiation;GO:0009636//response to toxic substance;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0032355//response to estradiol;GO:0031000//response to caffeine;GO:0051573//negative regulation of histone H3-K9 methylation;GO:0033189//response to vitamin A;GO:0051571//positive regulation of histone H3-K4 methylation;GO:0042493//response to drug;GO:0010212//response to ionizing radiation;GO:0014823//response to activity;GO:0006306//DNA methylation;GO:0010628//positive regulation of gene expression;GO:0071549//cellular response to dexamethasone stimulus;GO:0001666//response to hypoxia;GO:0045814//negative regulation of gene expression, epigenetic;GO:0071455//cellular response to hyperoxia;GO:0042220//response to cocaine","K17399//DNA (cytosine-5)-methyltransferase 3B [EC:2.1.1.37]","XP_008965737.1//PREDICTED: DNA (cytosine-5)-methyltransferase 3B isoform X5 [Pan paniscus];XP_011526956.1//PREDICTED: DNA (cytosine-5)-methyltransferase 3B isoform X2 [Homo sapiens];NP_001193985.1//DNA (cytosine-5)-methyltransferase 3B isoform 8 [Homo sapiens];NP_787046.1//DNA (cytosine-5)-methyltransferase 3B isoform 6 [Homo sapiens];XP_008965732.1//PREDICTED: DNA (cytosine-5)-methyltransferase 3B isoform X1 [Pan paniscus]","1//3;3//A2MP1;2//1"]
[56605,5070,1.82,1,-0.863938450423971,0.000318534591940668,"*",{"v":8.06606e-05,"d":"8.07E-05"},"ERO1B","NA","NA","NA","K10976//ERO1-like protein beta [EC:1.8.4.-]","AAF97547.1//endoplasmic reticulum oxidoreductin 1-Lbeta [Homo sapiens]","3//A2MP1"]
[51136,2031,6.6,3.63,-0.862496476250065,{"v":1.52663367774295e-05,"d":"1.53E-05"},"*",{"v":3.04868E-6,"d":"3.05E-06"},"RNFT1","GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0046872//metal ion binding;GO:0016740//transferase activity","GO:0016567//protein ubiquitination","K10264//F-box and WD-40 domain protein 8;K11981//E3 ubiquitin-protein ligase NRDP1 [EC:2.3.2.27];K14555//U3 small nucleolar RNA-associated protein 13","NP_057209.3//RING finger and transmembrane domain-containing protein 1 [Homo sapiens]","3//A2MP1"]
[5108,8213,8.72,4.81,-0.858291241006884,{"v":5.81446845665962e-28,"d":"5.81E-28"},"*",{"v":1.7217e-29,"d":"1.72E-29"},"PCM1","GO:0016020//membrane;GO:0031965//nuclear membrane;GO:0035869//ciliary transition zone;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0034451//centriolar satellite;GO:0005814//centriole;GO:0036064//ciliary basal body;GO:0000242//pericentriolar material;GO:0043234//protein complex;GO:0005829//cytosol;GO:0045177//apical part of cell","GO:0042802//identical protein binding","GO:0007098//centrosome cycle;GO:0090316//positive regulation of intracellular protein transport;GO:0034453//microtubule anchoring;GO:0060271//cilium assembly;GO:0097711//ciliary basal body-plasma membrane docking;GO:0035735//intraciliary transport involved in cilium assembly;GO:0031122//cytoplasmic microtubule organization;GO:0050768//negative regulation of neurogenesis;GO:0035176//social behavior;GO:1905515//non-motile cilium assembly;GO:0034454//microtubule anchoring at centrosome;GO:0001764//neuron migration;GO:0010389//regulation of G2/M transition of mitotic cell cycle;GO:0071539//protein localization to centrosome;GO:0000086//G2/M transition of mitotic cell cycle;GO:0022027//interkinetic nuclear migration;GO:0097150//neuronal stem cell population maintenance","K16537//pericentriolar material 1 protein","NP_001339563.1//pericentriolar material 1 protein isoform 6 [Homo sapiens];NP_001339579.1//pericentriolar material 1 protein isoform 19 [Homo sapiens];NP_001339585.1//pericentriolar material 1 protein isoform 21 [Homo sapiens];NP_001339571.1//pericentriolar material 1 protein isoform 14 [Homo sapiens];NP_001339570.1//pericentriolar material 1 protein isoform 13 [Homo sapiens];NP_001339578.1//pericentriolar material 1 protein isoform 18 [Homo sapiens];NP_001339576.1//pericentriolar material 1 protein isoform 17 [Homo sapiens];NP_001339572.1//pericentriolar material 1 protein isoform 15 [Homo sapiens];NP_001339574.1//pericentriolar material 1 protein isoform 16 [Homo sapiens];NP_006188.3//pericentriolar material 1 protein isoform 1 [Homo sapiens];NP_001339569.1//pericentriolar material 1 protein isoform 12 [Homo sapiens];NP_001339586.1//pericentriolar material 1 protein isoform 22 [Homo sapiens];NP_001339562.1//pericentriolar material 1 protein isoform 5 [Homo sapiens];NP_001339565.1//pericentriolar material 1 protein isoform 8 [Homo sapiens];NP_001339566.1//pericentriolar material 1 protein isoform 9 [Homo sapiens];NP_001302436.1//pericentriolar material 1 protein isoform 2 [Homo sapiens];NP_001302437.1//pericentriolar material 1 protein isoform 3 [Homo sapiens];NP_001339564.1//pericentriolar material 1 protein isoform 7 [Homo sapiens];NP_001339568.1//pericentriolar material 1 protein isoform 11 [Homo sapiens];NP_001339561.1//pericentriolar material 1 protein isoform 4 [Homo sapiens];NP_001339567.1//pericentriolar material 1 protein isoform 10 [Homo sapiens]","1//3;3//A2MP1"]
[23271,7363,6.67,3.68,-0.857980995127572,{"v":2.07307513540946e-18,"d":"2.07E-18"},"*",{"v":1.125176e-19,"d":"1.13E-19"},"CAMSAP2","GO:1990752//microtubule end;GO:0005874//microtubule;GO:0005829//cytosol","GO:0005516//calmodulin binding;GO:0008017//microtubule binding;GO:0051011//microtubule minus-end binding;GO:0030507//spectrin binding","GO:0033043//regulation of organelle organization;GO:0000226//microtubule cytoskeleton organization;GO:0031175//neuron projection development","K17493//calmodulin-regulated spectrin-associated protein","NP_001284637.1//calmodulin-regulated spectrin-associated protein 2 isoform 3 [Homo sapiens];NP_001284636.1//calmodulin-regulated spectrin-associated protein 2 isoform 1 [Homo sapiens];NP_982284.1//calmodulin-regulated spectrin-associated protein 2 isoform 2 [Homo sapiens]","1//3;2//1"]
[57670,12427,3.56,1.97,-0.853681611510022,{"v":2.49232245607108e-16,"d":"2.49E-16"},"*",{"v":1.58052E-17,"d":"1.58E-17"},"KIAA1549","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","NA","NA","K10955//mucin-2;K22023//mucin-6","NP_001158137.1//UPF0606 protein KIAA1549 isoform 2 [Homo sapiens];NP_065961.2//UPF0606 protein KIAA1549 isoform 1 [Homo sapiens]","1//3;2//1"]
[4035,14905,3.23,1.79,-0.851574577429669,{"v":1.16709710163934e-17,"d":"1.17E-17"},"*",{"v":6.6852e-19,"d":"6.69E-19"},"LRP1","GO:0016020//membrane;GO:0030425//dendrite;GO:0016323//basolateral plasma membrane;GO:0030666//endocytic vesicle membrane;GO:0098797//plasma membrane protein complex;GO:0043235//receptor complex;GO:0043025//neuronal cell body;GO:0005730//nucleolus;GO:0005887//integral component of plasma membrane;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005769//early endosome;GO:0005765//lysosomal membrane;GO:0005925//focal adhesion;GO:0030136//clathrin-coated vesicle;GO:0005905//clathrin-coated pit","GO:0002020//protease binding;GO:0003723//RNA binding;GO:0070325//lipoprotein particle receptor binding;GO:0004872//receptor activity;GO:0034185//apolipoprotein binding;GO:0016964//alpha-2 macroglobulin receptor activity;GO:0030226//apolipoprotein receptor activity;GO:0032050//clathrin heavy chain binding;GO:0043395//heparan sulfate proteoglycan binding;GO:0005041//low-density lipoprotein receptor activity;GO:0005044//scavenger receptor activity;GO:0042954//lipoprotein transporter activity;GO:0005509//calcium ion binding;GO:0032403//protein complex binding","GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0031623//receptor internalization;GO:0032956//regulation of actin cytoskeleton organization;GO:0045807//positive regulation of endocytosis;GO:0032092//positive regulation of protein binding;GO:0021987//cerebral cortex development;GO:1903078//positive regulation of protein localization to plasma membrane;GO:0032429//regulation of phospholipase A2 activity;GO:0042157//lipoprotein metabolic process;GO:0006909//phagocytosis;GO:0010715//regulation of extracellular matrix disassembly;GO:0043524//negative regulation of neuron apoptotic process;GO:0043277//apoptotic cell clearance;GO:0001523//retinoid metabolic process;GO:0006898//receptor-mediated endocytosis;GO:0006629//lipid metabolic process;GO:0010875//positive regulation of cholesterol efflux;GO:0097242//amyloid-beta clearance;GO:0030178//negative regulation of Wnt signaling pathway;GO:0035909//aorta morphogenesis;GO:1900223//positive regulation of amyloid-beta clearance;GO:2000587//negative regulation of platelet-derived growth factor receptor-beta signaling pathway;GO:0008283//cell proliferation;GO:0010977//negative regulation of neuron projection development;GO:0042953//lipoprotein transport;GO:0032374//regulation of cholesterol transport;GO:0010942//positive regulation of cell death;GO:0002265//astrocyte activation involved in immune response;GO:0051246//regulation of protein metabolic process;GO:1904646//cellular response to amyloid-beta;GO:0007568//aging;GO:0032370//positive regulation of lipid transport;GO:0014912//negative regulation of smooth muscle cell migration;GO:0045732//positive regulation of protein catabolic process;GO:1905167//positive regulation of lysosomal protein catabolic process;GO:0051222//positive regulation of protein transport;GO:0045056//transcytosis","K04550//low-density lipoprotein receptor-related protein 1 (alpha-2-macroglobulin receptor)","NP_002323.2//prolow-density lipoprotein receptor-related protein 1 preproprotein [Homo sapiens]","2//1"]
[201562,4169,24.73,13.71,-0.851033668610712,{"v":1.34225338333333e-36,"d":"1.34E-36"},"*",{"v":2.82332e-38,"d":"2.82E-38"},"HACD2","GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0102158//very-long-chain 3-hydroxyacyl-CoA dehydratase activity;GO:0018812//3-hydroxyacyl-CoA dehydratase activity;GO:0102345//3-hydroxy-lignoceroyl-CoA dehydratase activity;GO:0019899//enzyme binding;GO:0102344//3-hydroxy-behenoyl-CoA dehydratase activity;GO:0102343//3-hydroxy-arachidoyl-CoA dehydratase activity","GO:0030497//fatty acid elongation;GO:0030148//sphingolipid biosynthetic process;GO:0006633//fatty acid biosynthetic process;GO:0042761//very long-chain fatty acid biosynthetic process","K10703//very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:4.2.1.134]","NP_001316713.1//very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 isoform a [Homo sapiens];NP_001316712.1//very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 isoform a [Homo sapiens];XP_011827005.1//PREDICTED: very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 [Mandrillus leucophaeus];XP_007983767.1//PREDICTED: very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase 2 isoform X1 [Chlorocebus sabaeus]","1//3;4"]
[1519,2943,1.08,0.6,-0.84799690655495,0.0537903431578947,"*",0.0230328,"CTSO","GO:0005615//extracellular space;GO:0005764//lysosome","GO:0008234//cysteine-type peptidase activity;GO:0004197//cysteine-type endopeptidase activity","GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0006508//proteolysis","K01374//cathepsin O [EC:3.4.22.42]","EAX04883.1//cathepsin O [Homo sapiens]","2//1"]
[10153,3341,18.49,10.28,-0.846904960210318,{"v":5.7658825465288E-22,"d":"5.77E-22"},"*",{"v":2.44366E-23,"d":"2.44E-23"},"CEBPZ","GO:0005634//nucleus","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003723//RNA binding;GO:0003677//DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter","K14832//ribosome biogenesis protein MAK21","NP_005751.2//CCAAT/enhancer-binding protein zeta [Homo sapiens]","2//1"]
[253430,6133,1.94,1.08,-0.845025340023659,{"v":5.49791917867272e-05,"d":"5.50E-05"},"*",{"v":1.213576e-05,"d":"1.21E-05"},"IPMK","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus","GO:0005524//ATP binding;GO:0000823//inositol-1,4,5-trisphosphate 6-kinase activity;GO:0000825//inositol tetrakisphosphate 6-kinase activity;GO:0008440//inositol-1,4,5-trisphosphate 3-kinase activity;GO:0047326//inositol tetrakisphosphate 5-kinase activity;GO:0000824//inositol tetrakisphosphate 3-kinase activity","GO:0043647//inositol phosphate metabolic process","K00915//inositol-polyphosphate multikinase [EC:2.7.1.140 2.7.1.151]","NP_689416.1//inositol polyphosphate multikinase [Homo sapiens]",4]
[158055,2587,0.77,0.43,-0.840521785992804,0.159309376189314,"*",0.081759,"C9orf163","NA","NA","NA","K16628//collagen, type VII, alpha;K10361//myosin XV","EAW88240.1//hypothetical protein FLJ36779, partial [Homo sapiens]","2//1"]
[5966,7842,1.52,0.85,-0.838536577305884,{"v":7.00426954738015e-05,"d":"7.00E-05"},"*",{"v":1.573264e-05,"d":"1.57E-05"},"REL","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription factor complex;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0033256//I-kappaB/NF-kappaB complex","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0003677//DNA binding;GO:0001205//transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0038061//NIK/NF-kappaB signaling;GO:1901215//negative regulation of neuron death;GO:0034097//response to cytokine;GO:0010629//negative regulation of gene expression;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006954//inflammatory response;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045087//innate immune response;GO:0032688//negative regulation of interferon-beta production","K09254//c-Rel proto-oncogene protein","NP_001278675.1//proto-oncogene c-Rel isoform 2 [Homo sapiens];NP_002899.1//proto-oncogene c-Rel isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[6319,5473,299.73,167.69,-0.83786683253167,0,"*",0,"SCD","GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0005730//nucleolus;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0005506//iron ion binding;GO:0004768//stearoyl-CoA 9-desaturase activity;GO:0016491//oxidoreductase activity","GO:0006636//unsaturated fatty acid biosynthetic process;GO:0046949//fatty-acyl-CoA biosynthetic process;GO:1903966//monounsaturated fatty acid biosynthetic process;GO:0045540//regulation of cholesterol biosynthetic process","K00507//stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]","BAD92219.1//stearoyl-CoA desaturase variant, partial [Homo sapiens]",4]
[7434,3793,0.66,0.37,-0.834940753729504,0.096893609521248,"*",0.0451046,"VIPR2","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004999//vasoactive intestinal polypeptide receptor activity;GO:0004930//G-protein coupled receptor activity","GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0007190//activation of adenylate cyclase activity;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0007166//cell surface receptor signaling pathway","K04590//vasoactive intestinal peptide receptor 2","NP_001291451.1//vasoactive intestinal polypeptide receptor 2 isoform 2 precursor [Homo sapiens];NP_003373.2//vasoactive intestinal polypeptide receptor 2 isoform 1 precursor [Homo sapiens];NP_001295188.1//vasoactive intestinal polypeptide receptor 2 isoform 3 [Homo sapiens]","4;1//3"]
[399967,1640,0.73,0.41,-0.832272554261934,0.348159208234689,"*",0.211742,"PATE2","GO:0005615//extracellular space","NA","NA","NA","NP_997720.1//prostate and testis expressed protein 2 precursor [Homo sapiens]","2//1"]
[23380,6306,9.52,5.35,-0.831422682019434,{"v":5.07172129970326e-22,"d":"5.07E-22"},"*",{"v":2.13994e-23,"d":"2.14E-23"},"SRGAP2","GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0030054//cell junction;GO:0014069//postsynaptic density;GO:0030027//lamellipodium;GO:0005737//cytoplasm;GO:0044327//dendritic spine head;GO:0045335//phagocytic vesicle;GO:0005829//cytosol;GO:0005743//mitochondrial inner membrane;GO:0005886//plasma membrane;GO:0045211//postsynaptic membrane","GO:0048365//Rac GTPase binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0005096//GTPase activator activity","GO:0034446//substrate adhesion-dependent cell spreading;GO:0007165//signal transduction;GO:0046847//filopodium assembly;GO:0060996//dendritic spine development;GO:0043547//positive regulation of GTPase activity;GO:2001223//negative regulation of neuron migration;GO:0048812//neuron projection morphogenesis;GO:0021816//extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration;GO:0003363//lamellipodium assembly involved in ameboidal cell migration;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0051014//actin filament severing","K07526//SLIT-ROBO Rho GTPase activating protein","NP_001164108.1//SLIT-ROBO Rho GTPase-activating protein 2 isoform c [Homo sapiens];NP_001287881.1//SLIT-ROBO Rho GTPase-activating protein 2 isoform d [Homo sapiens];NP_056141.2//SLIT-ROBO Rho GTPase-activating protein 2 isoform a [Homo sapiens]","1//3;4;3//A2MP1"]
[57337,4708,0.8,0.45,-0.830074998557688,0.0214159943093466,"*",0.0081044,"SENP7","GO:0005634//nucleus;GO:0005622//intracellular;GO:0005886//plasma membrane","GO:0008234//cysteine-type peptidase activity;GO:0004930//G-protein coupled receptor activity","GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway","K08596//sentrin-specific protease 7 [EC:3.4.22.68]","NP_065705.3//sentrin-specific protease 7 isoform 1 [Homo sapiens];XP_016862418.1//PREDICTED: sentrin-specific protease 7 isoform X12 [Homo sapiens];NP_001070671.1//sentrin-specific protease 7 isoform 2 [Homo sapiens];XP_005247719.1//PREDICTED: sentrin-specific protease 7 isoform X9 [Homo sapiens];NP_001269730.1//sentrin-specific protease 7 isoform 3 [Homo sapiens]","4;1//3;2//1"]
[5412,4355,3.62,2.04,-0.82742054511171,{"v":4.26727448803828e-06,"d":"4.27E-06"},"*",{"v":7.81648e-07,"d":"7.82E-07"},"UBL3","GO:0070062//extracellular exosome;GO:0005622//intracellular;GO:0005886//plasma membrane","NA","NA","K14802//phospholipid-transporting ATPase [EC:3.6.3.1]","XP_008515626.1//PREDICTED: ubiquitin-like protein 3 [Equus przewalskii]","3//A2MP1"]
[7840,12928,1.33,0.75,-0.826463745005309,{"v":1.19015220699926e-06,"d":"1.19E-06"},"*",{"v":2.00122E-7,"d":"2.00E-07"},"ALMS1","GO:0005929//cilium;GO:0000922//spindle pole;GO:0005829//cytosol;GO:0005813//centrosome","GO:0051393//alpha-actinin binding","GO:0016197//endosomal transport;GO:0010389//regulation of G2/M transition of mitotic cell cycle;GO:0097711//ciliary basal body-plasma membrane docking;GO:0000086//G2/M transition of mitotic cell cycle;GO:0051492//regulation of stress fiber assembly","K16741//alstrom syndrome protein 1","NP_055935.4//Alstrom syndrome protein 1 [Homo sapiens]",4]
[4303,3365,1.17,0.66,-0.825970600224951,0.0527776837072885,"*",0.0225298,"FOXO4","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0005737//cytoplasm","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0003677//DNA binding;GO:0042802//identical protein binding;GO:1990841//promoter-specific chromatin binding;GO:0043565//sequence-specific DNA binding;GO:0008134//transcription factor binding;GO:0019899//enzyme binding;GO:0003700//DNA binding transcription factor activity;GO:0008013//beta-catenin binding","GO:0007095//mitotic G2 DNA damage checkpoint;GO:0008286//insulin receptor signaling pathway;GO:0006355//regulation of transcription, DNA-templated;GO:1990785//response to water-immersion restraint stress;GO:0051151//negative regulation of smooth muscle cell differentiation;GO:0007050//cell cycle arrest;GO:0016579//protein deubiquitination;GO:0070317//negative regulation of G0 to G1 transition;GO:0014911//positive regulation of smooth muscle cell migration;GO:0008285//negative regulation of cell proliferation;GO:0016525//negative regulation of angiogenesis;GO:0006351//transcription, DNA-templated;GO:0007517//muscle organ development;GO:0006366//transcription from RNA polymerase II promoter;GO:0007568//aging;GO:0048863//stem cell differentiation;GO:0071158//positive regulation of cell cycle arrest;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0031667//response to nutrient levels","K12358//forkhead box protein O4","NP_001164402.1//forkhead box protein O4 isoform 2 [Homo sapiens];NP_005929.2//forkhead box protein O4 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[4038,8244,3.24,1.83,-0.824150164600582,{"v":1.04131728682171e-09,"d":"1.04E-09"},"*",{"v":1.1773e-10,"d":"1.18E-10"},"LRP4","GO:0030425//dendrite;GO:0031594//neuromuscular junction;GO:0014069//postsynaptic density;GO:0097060//synaptic membrane;GO:0043235//receptor complex;GO:0043025//neuronal cell body;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0016600//flotillin complex;GO:0005886//plasma membrane","GO:0097110//scaffold protein binding;GO:0005509//calcium ion binding;GO:0042813//Wnt-activated receptor activity;GO:0030971//receptor tyrosine kinase binding;GO:0034185//apolipoprotein binding;GO:0017147//Wnt-protein binding;GO:0042803//protein homodimerization activity","GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0001822//kidney development;GO:0044332//Wnt signaling pathway involved in dorsal/ventral axis specification;GO:0042733//embryonic digit morphogenesis;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0006897//endocytosis;GO:0051124//synaptic growth at neuromuscular junction;GO:0050808//synapse organization;GO:0071340//skeletal muscle acetylcholine-gated channel clustering;GO:0097105//presynaptic membrane assembly;GO:0097104//postsynaptic membrane assembly;GO:0030509//BMP signaling pathway;GO:0051290//protein heterotetramerization;GO:0048813//dendrite morphogenesis;GO:0042475//odontogenesis of dentin-containing tooth;GO:1901631//positive regulation of presynaptic membrane organization;GO:0060173//limb development;GO:0030279//negative regulation of ossification;GO:1904395//positive regulation of skeletal muscle acetylcholine-gated channel clustering;GO:0050771//negative regulation of axonogenesis;GO:0009954//proximal/distal pattern formation;GO:0001942//hair follicle development","K20051//low-density lipoprotein receptor-related protein 4","XP_019268022.1//PREDICTED: low-density lipoprotein receptor-related protein 4 [Panthera pardus]","3//A2MP1"]
[83478,4644,0.92,0.52,-0.823122237915921,0.0168903945584726,"*",0.00620252,"ARHGAP24","GO:0005856//cytoskeleton;GO:0042995//cell projection;GO:0005925//focal adhesion;GO:0005829//cytosol","GO:0005096//GTPase activator activity","GO:0007165//signal transduction;GO:0030154//cell differentiation;GO:0001525//angiogenesis;GO:0051056//regulation of small GTPase mediated signal transduction","K20642//Rho GTPase-activating protein 22/24/25","NP_112595.2//rho GTPase-activating protein 24 isoform 2 [Homo sapiens];NP_001274734.1//rho GTPase-activating protein 24 isoform 4 [Homo sapiens];NP_001333022.1//rho GTPase-activating protein 24 isoform 5 [Homo sapiens];XP_011807167.1//PREDICTED: rho GTPase-activating protein 24 isoform X2 [Colobus angolensis palliatus]","1//3;2//1"]
[22893,4615,6.09,3.45,-0.819845866240801,{"v":5.48388703788748e-10,"d":"5.48E-10"},"*",{"v":5.9803e-11,"d":"5.98E-11"},"BAHD1","GO:0005654//nucleoplasm;GO:0000785//chromatin;GO:0005677//chromatin silencing complex","GO:0003682//chromatin binding;GO:0000976//transcription regulatory region sequence-specific DNA binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0006342//chromatin silencing;GO:0016569//covalent chromatin modification;GO:0031507//heterochromatin assembly;GO:0006351//transcription, DNA-templated","K04533//huntingtin","XP_016783426.1//PREDICTED: bromo adjacent homology domain-containing 1 protein isoform X1 [Pan troglodytes];XP_016783427.1//PREDICTED: bromo adjacent homology domain-containing 1 protein isoform X2 [Pan troglodytes]","4;1//3"]
[94134,4964,9.21,5.22,-0.819151349521451,{"v":1.90700516363636e-15,"d":"1.91E-15"},"*",{"v":1.286936e-16,"d":"1.29E-16"},"ARHGAP12","GO:0005829//cytosol;GO:0001891//phagocytic cup","GO:0005096//GTPase activator activity","GO:0002011//morphogenesis of an epithelial sheet;GO:0006911//phagocytosis, engulfment;GO:0007015//actin filament organization;GO:0007165//signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0051058//negative regulation of small GTPase mediated signal transduction","K20636//Rho GTPase-activating protein 12/27","NP_001257627.1//rho GTPase-activating protein 12 isoform 5 [Homo sapiens];NP_001257625.1//rho GTPase-activating protein 12 isoform 3 [Homo sapiens];NP_001257628.1//rho GTPase-activating protein 12 isoform 6 [Homo sapiens];NP_001257626.1//rho GTPase-activating protein 12 isoform 4 [Homo sapiens];NP_001257624.1//rho GTPase-activating protein 12 isoform 2 [Homo sapiens];NP_060757.4//rho GTPase-activating protein 12 isoform 1 [Homo sapiens]","6;1//3"]
[135228,9170,11.74,6.67,-0.815673741925467,{"v":1.17798474865672E-36,"d":"1.18E-36"},"*",{"v":2.47042e-38,"d":"2.47E-38"},"CD109","GO:0005615//extracellular space;GO:0009986//cell surface;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0031225//anchored component of membrane;GO:0031092//platelet alpha granule membrane","GO:0004867//serine-type endopeptidase inhibitor activity;GO:0050431//transforming growth factor beta binding","GO:0010839//negative regulation of keratinocyte proliferation;GO:0006501//C-terminal protein lipidation;GO:0072675//osteoclast fusion;GO:0045616//regulation of keratinocyte differentiation;GO:0002576//platelet degranulation;GO:0001933//negative regulation of protein phosphorylation;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0061045//negative regulation of wound healing;GO:0001942//hair follicle development","K06530//CD109 antigen","XP_018884366.1//PREDICTED: CD109 antigen, partial [Gorilla gorilla gorilla];CAE46045.1//hypothetical protein, partial [Homo sapiens]","4;2//1"]
[6782,4001,5.15,2.93,-0.813671767648333,{"v":1.88239814687369e-07,"d":"1.88E-07"},"*",{"v":2.80816e-08,"d":"2.81E-08"},"HSPA13","GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0005783//endoplasmic reticulum","GO:0005524//ATP binding","NA","K09491//stress 70 protein chaperone microsome-associated 60kDa protein","NP_008879.3//heat shock 70 kDa protein 13 precursor [Homo sapiens]",4]
[9936,3821,2.23,1.27,-0.812215213148139,0.000842574092643052,"*",2.32296E-4,"CD302","GO:0016020//membrane;GO:0005887//integral component of plasma membrane;GO:0005938//cell cortex;GO:0016021//integral component of membrane;GO:0005902//microvillus;GO:0030175//filopodium","GO:0030246//carbohydrate binding;GO:0004888//transmembrane signaling receptor activity","GO:0006909//phagocytosis","K06722//CD302 antigen;K06559//lymphocyte antigen 75","NP_001185693.1//CD302 antigen isoform 3 precursor [Homo sapiens];NP_001185692.1//CD302 antigen isoform 2 precursor [Homo sapiens];NP_055695.2//CD302 antigen isoform 1 precursor [Homo sapiens]","1//3;4"]
[151195,3676,13.74,7.84,-0.809456444702892,{"v":7.90584098467824e-17,"d":"7.91E-17"},"*",{"v":4.84526e-18,"d":"4.85E-18"},"CCNYL1","GO:0005886//plasma membrane","GO:0019901//protein kinase binding","GO:0030317//flagellated sperm motility;GO:0007283//spermatogenesis;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity","K12491//Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1/3;K04613//vomeronasal 2 receptor;K18468//vacuolar protein sorting-associated protein 35","NP_001317147.1//cyclin-Y-like protein 1 isoform 3 [Homo sapiens];NP_001135772.1//cyclin-Y-like protein 1 isoform 1 [Homo sapiens];XP_018878136.1//PREDICTED: cyclin-Y-like protein 1 isoform X1 [Gorilla gorilla gorilla]","1//3;2//1"]
[161436,7171,0.21,0.12,-0.807354922057604,0.263840695443121,"*",0.151146,"EML5","NA","NA","NA","K18597//echinoderm microtubule-associated protein-like 5","XP_014701358.1//PREDICTED: echinoderm microtubule-associated protein-like 5 isoform X2 [Equus asinus]","2//1"]
[3800,6958,0.07,0.04,-0.807354922057604,0.499184970409918,"*",0.345342,"KIF5C","GO:0005874//microtubule;GO:0035253//ciliary rootlet;GO:0005737//cytoplasm;GO:0043005//neuron projection;GO:0005871//kinesin complex","GO:0005524//ATP binding;GO:0003777//microtubule motor activity;GO:0008017//microtubule binding;GO:0008574//ATP-dependent microtubule motor activity, plus-end-directed","GO:0007018//microtubule-based movement;GO:0008045//motor neuron axon guidance;GO:0008104//protein localization;GO:0006996//organelle organization;GO:0030705//cytoskeleton-dependent intracellular transport;GO:0007411//axon guidance;GO:0051028//mRNA transport","K10396//kinesin family member 5","NP_004513.1//kinesin heavy chain isoform 5C [Homo sapiens]","2//1"]
[2740,6698,0.07,0.04,-0.807354922057604,0.49855337623136,"*",0.345342,"GLP1R","GO:0005887//integral component of plasma membrane;GO:0005622//intracellular;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004967//glucagon receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0044508//glucagon-like peptide 1 receptor activity","GO:0045777//positive regulation of blood pressure;GO:0006950//response to stress;GO:0007166//cell surface receptor signaling pathway;GO:0050796//regulation of insulin secretion;GO:0019933//cAMP-mediated signaling;GO:0007190//activation of adenylate cyclase activity;GO:0008016//regulation of heart contraction;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007611//learning or memory","K04581//glucagon-like peptide 1 receptor","NP_002053.3//glucagon-like peptide 1 receptor precursor [Homo sapiens]",4]
[83540,1900,14.36,8.21,-0.806601622045247,{"v":6.99009236856981e-10,"d":"6.99E-10"},"*",{"v":7.741e-11,"d":"7.74E-11"},"NUF2","GO:0016020//membrane;GO:0005634//nucleus;GO:0005829//cytosol;GO:0000777//condensed chromosome kinetochore;GO:0031262//Ndc80 complex;GO:0000775//chromosome, centromeric region","NA","GO:0000278//mitotic cell cycle;GO:0007059//chromosome segregation;GO:0007062//sister chromatid cohesion;GO:0051301//cell division","K11548//kinetochore protein Nuf2","NP_113611.2//kinetochore protein Nuf2 [Homo sapiens]","3//A2MP1;2//1"]
[1870,5201,6.31,3.61,-0.805641168095378,{"v":3.82075888073395e-11,"d":"3.82E-11"},"*",{"v":3.64998e-12,"d":"3.65E-12"},"E2F2","GO:0090575//RNA polymerase II transcription factor complex;GO:0005654//nucleoplasm","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0008134//transcription factor binding;GO:0003700//DNA binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0001047//core promoter binding","GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0051726//regulation of cell cycle;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:1990086//lens fiber cell apoptotic process;GO:0007049//cell cycle","K09389//transcription factor E2F2","NP_004082.1//transcription factor E2F2 [Homo sapiens]","3//A2MP1"]
[5287,7606,5.22,2.99,-0.803904322371779,{"v":3.19762261454261e-13,"d":"3.20E-13"},"*",{"v":2.56026e-14,"d":"2.56E-14"},"PIK3C2B","GO:0005654//nucleoplasm;GO:0005783//endoplasmic reticulum;GO:0030139//endocytic vesicle;GO:0005942//phosphatidylinositol 3-kinase complex;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0001727//lipid kinase activity;GO:0005524//ATP binding;GO:0016303//1-phosphatidylinositol-3-kinase activity;GO:0016301//kinase activity;GO:0035005//1-phosphatidylinositol-4-phosphate 3-kinase activity;GO:0035091//phosphatidylinositol binding","GO:0016477//cell migration;GO:1905037//autophagosome organization;GO:0009267//cellular response to starvation;GO:0036092//phosphatidylinositol-3-phosphate biosynthetic process;GO:0043491//protein kinase B signaling;GO:0006661//phosphatidylinositol biosynthetic process;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0046854//phosphatidylinositol phosphorylation;GO:0048015//phosphatidylinositol-mediated signaling","K00923//phosphatidylinositol-4-phosphate 3-kinase [EC:2.7.1.154]","NP_002637.3//phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta [Homo sapiens]","3//A2MP1"]
[2187,2994,1.9,1.09,-0.801671283554021,0.0104254670774775,"*",0.00362222,"FANCB","GO:0005654//nucleoplasm;GO:0043240//Fanconi anaemia nuclear complex","NA","GO:0036297//interstrand cross-link repair","K10889//fanconi anemia group B protein","NP_689846.1//Fanconi anemia group B protein [Homo sapiens]","1//3;3//A2MP1;2//1"]
[57669,6052,1.95,1.12,-0.799975391692006,0.000148650389926548,"*",{"v":3.54736e-05,"d":"3.55E-05"},"EPB41L5","GO:0005856//cytoskeleton;GO:0005925//focal adhesion;GO:0005829//cytosol;GO:0032587//ruffle membrane;GO:0005912//adherens junction;GO:0005886//plasma membrane","GO:0019904//protein domain specific binding;GO:0008092//cytoskeletal protein binding;GO:0005200//structural constituent of cytoskeleton","GO:0048617//embryonic foregut morphogenesis;GO:0031032//actomyosin structure organization;GO:0032525//somite rostral/caudal axis specification;GO:0010608//posttranscriptional regulation of gene expression;GO:0032092//positive regulation of protein binding;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0022408//negative regulation of cell-cell adhesion;GO:0010634//positive regulation of epithelial cell migration;GO:0070986//left/right axis specification;GO:0032091//negative regulation of protein binding;GO:0007509//mesoderm migration involved in gastrulation;GO:0001837//epithelial to mesenchymal transition;GO:0070201//regulation of establishment of protein localization;GO:0048339//paraxial mesoderm development;GO:0007492//endoderm development;GO:0009826//unidimensional cell growth;GO:0051894//positive regulation of focal adhesion assembly;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0001701//in utero embryonic development;GO:0007398//ectoderm development;GO:0006931//substrate-dependent cell migration, cell attachment to substrate;GO:0048319//axial mesoderm morphogenesis;GO:0003383//apical constriction;GO:0001839//neural plate morphogenesis","K21111//band 4.1-like protein 4B","NP_001317239.1//band 4.1-like protein 5 isoform 5 [Homo sapiens];NP_065960.2//band 4.1-like protein 5 isoform 1 [Homo sapiens];NP_001171866.1//band 4.1-like protein 5 isoform 2 [Homo sapiens];XP_016805099.1//PREDICTED: band 4.1-like protein 5 isoform X12 [Pan troglodytes];NP_001171867.1//band 4.1-like protein 5 isoform 3 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[4811,5903,3.6,2.07,-0.79836613883035,{"v":1.98928120217664e-07,"d":"1.99E-07"},"*",{"v":2.97508e-08,"d":"2.98E-08"},"NID1","GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0005605//basal lamina;GO:0005576//extracellular region;GO:0071944//cell periphery;GO:0005604//basement membrane","GO:0043237//laminin-1 binding;GO:0005518//collagen binding;GO:0005509//calcium ion binding;GO:0043236//laminin binding;GO:0043394//proteoglycan binding","GO:0022617//extracellular matrix disassembly;GO:0007160//cell-matrix adhesion;GO:0071711//basement membrane organization;GO:0032836//glomerular basement membrane development;GO:0030198//extracellular matrix organization;GO:0010811//positive regulation of cell-substrate adhesion","K06826//nidogen (entactin)","NP_002499.2//nidogen-1 precursor [Homo sapiens]","2//1"]
[8661,6726,28.22,16.25,-0.796278269794085,{"v":5.84917053636364e-60,"d":"5.85E-60"},"*",{"v":6.44456e-62,"d":"6.44E-62"},"EIF3A","GO:0016020//membrane;GO:0005634//nucleus;GO:0005874//microtubule;GO:0005737//cytoplasm;GO:0016282//eukaryotic 43S preinitiation complex;GO:0071541//eukaryotic translation initiation factor 3 complex, eIF3m;GO:0043614//multi-eIF complex;GO:0005730//nucleolus;GO:0071540//eukaryotic translation initiation factor 3 complex, eIF3e;GO:0005829//cytosol;GO:0033290//eukaryotic 48S preinitiation complex;GO:0005852//eukaryotic translation initiation factor 3 complex","GO:0003743//translation initiation factor activity;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0030971//receptor tyrosine kinase binding;GO:0005198//structural molecule activity","GO:0075522//IRES-dependent viral translational initiation;GO:0075525//viral translational termination-reinitiation;GO:0001731//formation of translation preinitiation complex;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0006413//translational initiation;GO:0006446//regulation of translational initiation;GO:0001732//formation of cytoplasmic translation initiation complex;GO:0002188//translation reinitiation","K03254//translation initiation factor 3 subunit A","NP_003741.1//eukaryotic translation initiation factor 3 subunit A [Homo sapiens]","3//A2MP1"]
[9444,9826,7.27,4.19,-0.795005120220243,{"v":1.56867152755418e-22,"d":"1.57E-22"},"*",{"v":6.34382e-24,"d":"6.34E-24"},"QKI","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0003729//mRNA binding;GO:0003723//RNA binding;GO:0017124//SH3 domain binding","GO:0042552//myelination;GO:0006397//mRNA processing;GO:0030154//cell differentiation;GO:0042759//long-chain fatty acid biosynthetic process;GO:0007286//spermatid development;GO:0010628//positive regulation of gene expression;GO:0006417//regulation of translation;GO:0008366//axon ensheathment;GO:0051028//mRNA transport;GO:0061158//3'-UTR-mediated mRNA destabilization;GO:0042692//muscle cell differentiation;GO:0007275//multicellular organism development;GO:0008380//RNA splicing;GO:0001570//vasculogenesis","K14945//protein quaking","AAF63414.1//QUAKING isoform 6 [Homo sapiens];AAF63413.1//QUAKING isoform 2 [Homo sapiens];AAF63417.1//QUAKING isoform 3 [Homo sapiens];NP_996737.1//protein quaking isoform 4 [Homo sapiens]","1//3;2//1"]
[26149,4135,1.3,0.75,-0.793549122532574,0.0104799679006122,"*",0.00364378,"ZNF658","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0042254//ribosome biogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0071294//cellular response to zinc ion;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","NP_149350.3//zinc finger protein 658 [Homo sapiens]","6;1//3"]
[54905,2354,0.64,0.37,-0.79054663437105,0.244129689813167,"*",0.1374242,"CYP2W1","GO:0005788//endoplasmic reticulum lumen;GO:0009986//cell surface;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane","GO:0008395//steroid hydroxylase activity;GO:0020037//heme binding;GO:0005506//iron ion binding;GO:0004497//monooxygenase activity;GO:0008392//arachidonic acid epoxygenase activity","GO:0006805//xenobiotic metabolic process;GO:0043390//aflatoxin B1 metabolic process;GO:0019373//epoxygenase P450 pathway","K07423//cytochrome P450 family 2 subfamily W polypeptide 1","NP_060251.2//cytochrome P450 2W1 precursor [Homo sapiens]","2//1"]
[57551,11779,8.03,4.65,-0.788169271521921,{"v":4.62654501552106e-29,"d":"4.63E-29"},"*",{"v":1.30623E-30,"d":"1.31E-30"},"TAOK1","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0004709//MAP kinase kinase kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0016301//kinase activity;GO:0016740//transferase activity","GO:0046330//positive regulation of JNK cascade;GO:0007399//nervous system development;GO:0007346//regulation of mitotic cell cycle;GO:0006281//DNA repair;GO:0006468//protein phosphorylation;GO:0032874//positive regulation of stress-activated MAPK cascade;GO:0097194//execution phase of apoptosis;GO:0007062//sister chromatid cohesion;GO:0051493//regulation of cytoskeleton organization;GO:0031098//stress-activated protein kinase signaling cascade;GO:0006974//cellular response to DNA damage stimulus;GO:0031572//G2 DNA damage checkpoint;GO:0042981//regulation of apoptotic process","K04429//thousand and one amino acid protein kinase [EC:2.7.11.1]","NP_065842.1//serine/threonine-protein kinase TAO1 isoform 1 [Homo sapiens];NP_079418.1//serine/threonine-protein kinase TAO1 isoform 2 [Homo sapiens]","1//3;2//1"]
[10194,4897,3,1.74,-0.785875194647153,{"v":1.75143570737756e-05,"d":"1.75E-05"},"*",{"v":3.53708e-06,"d":"3.54E-06"},"TSHZ1","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0009952//anterior/posterior pattern specification;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0042474//middle ear morphogenesis;GO:0007275//multicellular organism development;GO:0006351//transcription, DNA-templated;GO:0060023//soft palate development","K09236//teashirt","XP_001137580.2//PREDICTED: teashirt homolog 1 isoform X1 [Pan troglodytes];NP_001295139.1//teashirt homolog 1 isoform 1 [Homo sapiens]","1//3;5"]
[23089,6628,27.57,16,-0.785027362235466,{"v":2.04256443560209e-56,"d":"2.04E-56"},"*",{"v":2.44228E-58,"d":"2.44E-58"},"PEG10","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0003676//nucleic acid binding","GO:0030154//cell differentiation;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0001890//placenta development;GO:0006915//apoptotic process","K05748//WAS protein family, member 2","XP_021545272.1//retrotransposon-derived protein PEG10 isoform X1 [Neomonachus schauinslandi]","1//3;3//A2MP1;2//1"]
[4437,4472,6.2,3.6,-0.784271308944563,{"v":4.07455664e-09,"d":"4.07E-09"},"*",{"v":4.91018e-10,"d":"4.91E-10"},"MSH3","GO:0016020//membrane;GO:0005654//nucleoplasm;GO:0032302//MutSbeta complex","GO:0000406//double-strand/single-strand DNA junction binding;GO:0003684//damaged DNA binding;GO:0005524//ATP binding;GO:0000404//heteroduplex DNA loop binding;GO:0000403//Y-form DNA binding;GO:0008094//DNA-dependent ATPase activity;GO:0019899//enzyme binding","GO:0045910//negative regulation of DNA recombination;GO:0006281//DNA repair;GO:0006298//mismatch repair;GO:0016447//somatic recombination of immunoglobulin gene segments;GO:0043570//maintenance of DNA repeat elements;GO:0051096//positive regulation of helicase activity","K08736//DNA mismatch repair protein MSH3","NP_002430.3//DNA mismatch repair protein Msh3 [Homo sapiens]",4]
[83543,3440,1.41,0.82,-0.78199934778071,0.0216149606677686,"*",0.00818646,"AIF1L","GO:0005856//cytoskeleton;GO:0070062//extracellular exosome;GO:0005925//focal adhesion;GO:0032587//ruffle membrane;GO:0005737//cytoplasm;GO:0005884//actin filament;GO:0043234//protein complex;GO:0015629//actin cytoskeleton","GO:0051015//actin filament binding;GO:0005509//calcium ion binding","NA","K18617//allograft inflammatory factor 1","NP_001172024.1//allograft inflammatory factor 1-like isoform 3 [Homo sapiens];NP_001172025.1//allograft inflammatory factor 1-like isoform 4 [Homo sapiens];NP_113614.1//allograft inflammatory factor 1-like isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[22828,5112,7.66,4.46,-0.780300682004652,{"v":1.90294300448e-13,"d":"1.90E-13"},"*",{"v":1.489094e-14,"d":"1.49E-14"},"SCAF8","GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0016363//nuclear matrix","GO:0043175//RNA polymerase core enzyme binding;GO:0003723//RNA binding","GO:0006397//mRNA processing;GO:0008380//RNA splicing","K13191//RNA-binding protein 16;K16847//T-lymphoma invasion and metastasis-inducing protein 2","XP_008005850.1//PREDICTED: protein SCAF8 isoform X4 [Chlorocebus sabaeus];NP_001273117.1//protein SCAF8 isoform a [Homo sapiens]","1//3;4"]
[23181,6014,4.36,2.54,-0.779499638004761,{"v":1.4373614695082E-9,"d":"1.44E-09"},"*",{"v":1.646658e-10,"d":"1.65E-10"},"DIP2A","NA","GO:0003824//catalytic activity","GO:0008152//metabolic process","K05637//laminin, alpha 1/2;K09291//nucleoprotein TPR","XP_020140384.1//disco-interacting protein 2 homolog A isoform X4 [Microcebus murinus];EAX09272.1//DIP2 disco-interacting protein 2 homolog A (Drosophila), isoform CRA_b, partial [Homo sapiens];XP_008062757.1//disco-interacting protein 2 homolog A isoform X2 [Carlito syrichta];XP_012969374.1//disco-interacting protein 2 homolog A isoform X5 [Mesocricetus auratus];XP_008062756.1//disco-interacting protein 2 homolog A isoform X1 [Carlito syrichta];XP_004416258.1//PREDICTED: disco-interacting protein 2 homolog A isoform X3 [Odobenus rosmarus divergens]","1//3;3//A2MP1;2//1"]
[54331,3899,1.44,0.84,-0.777607578663552,0.0165784747122118,"*",0.00607656,"GNG2","NA","NA","NA","K07826//guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2","XP_010630857.1//PREDICTED: guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 isoform X1 [Fukomys damarensis];EAW65665.1//guanine nucleotide binding protein (G protein), gamma 2, isoform CRA_c [Homo sapiens]","1//3;4"]
[221035,5205,11.81,6.91,-0.773251349008899,{"v":7.5784099497006e-19,"d":"7.58E-19"},"*",{"v":3.96142e-20,"d":"3.96E-20"},"REEP3","GO:0005874//microtubule;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","NA","GO:0007084//mitotic nuclear envelope reassembly;GO:0051301//cell division;GO:0006998//nuclear envelope organization","K17338//receptor expression-enhancing protein 1/2/3/4","NP_001001330.1//receptor expression-enhancing protein 3 [Homo sapiens]","2//1"]
[55669,3527,6.49,3.8,-0.772219059668191,{"v":1.70644342664418e-07,"d":"1.71E-07"},"*",{"v":2.53392E-8,"d":"2.53E-08"},"MFN1","GO:0016021//integral component of membrane;GO:0005741//mitochondrial outer membrane","GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0008053//mitochondrial fusion","K21356//mitofusin 1 [EC:3.6.5.-]","XP_017361786.1//PREDICTED: mitofusin-1 isoform X1 [Cebus capucinus imitator]","2//1"]
[3652,3207,1.81,1.06,-0.771925432520006,0.00887716001467621,"*",0.00302926,"IPP","GO:0015629//actin cytoskeleton;GO:0005737//cytoplasm;GO:0031463//Cul3-RING ubiquitin ligase complex","GO:0003779//actin binding","GO:0016567//protein ubiquitination","K13956//actin-binding protein IPP","NP_001138821.1//actin-binding protein IPP isoform 2 [Homo sapiens];NP_005888.1//actin-binding protein IPP isoform 1 [Homo sapiens]","1//3;2//1"]
[5775,11381,1.55,0.91,-0.768329765075541,{"v":5.74851155942417e-06,"d":"5.75E-06"},"*",{"v":1.074922E-6,"d":"1.07E-06"},"PTPN4","GO:0005856//cytoskeleton;GO:0009898//cytoplasmic side of plasma membrane;GO:0005737//cytoplasm","GO:0004726//non-membrane spanning protein tyrosine phosphatase activity;GO:0008092//cytoskeletal protein binding","GO:0006470//protein dephosphorylation","K18037//tyrosine-protein phosphatase non-receptor type 4 [EC:3.1.3.48]","XP_005572994.2//PREDICTED: tyrosine-protein phosphatase non-receptor type 4 isoform X2 [Macaca fascicularis]","3//A2MP1"]
[9873,4507,4.36,2.56,-0.768184324776927,{"v":1.5983599618908e-06,"d":"1.60E-06"},"*",{"v":2.73064e-07,"d":"2.73E-07"},"FCHSD2","GO:0031594//neuromuscular junction;GO:0055037//recycling endosome","NA","GO:0030833//regulation of actin filament polymerization;GO:0007274//neuromuscular synaptic transmission","K20125//F-BAR and double SH3 domains protein","NP_055639.2//F-BAR and double SH3 domains protein 2 [Homo sapiens]","2//1"]
[25903,3796,0.17,0.1,-0.765534746362977,0.582828036992636,"*",0.426084,"OLFML2B","GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix","GO:0050840//extracellular matrix binding","GO:0030198//extracellular matrix organization","K04592//latrophilin 1","NP_001284642.1//olfactomedin-like protein 2B isoform 1 precursor [Homo sapiens];NP_056256.1//olfactomedin-like protein 2B isoform 2 precursor [Homo sapiens];NP_001334629.1//olfactomedin-like protein 2B isoform 3 precursor [Homo sapiens]","1//3;2//1"]
[134637,7147,1.58,0.93,-0.764621937069072,0.000620359595423768,"*",0.0001663328,"ADAT2","NA","GO:0008270//zinc ion binding;GO:0008251//tRNA-specific adenosine deaminase activity","GO:0002100//tRNA wobble adenosine to inosine editing","K15441//tRNA-specific adenosine deaminase 2 [EC:3.5.4.-]","XP_001924271.1//tRNA-specific adenosine deaminase 2 [Sus scrofa];XP_008577084.1//PREDICTED: tRNA-specific adenosine deaminase 2 [Galeopterus variegatus]","1//3;2//1"]
[26115,11747,4.74,2.79,-0.764621937069072,{"v":6.01865551129363E-17,"d":"6.02E-17"},"*",{"v":3.66982e-18,"d":"3.67E-18"},"TANC2","NA","NA","GO:0001701//in utero embryonic development","K21440//ankyrin repeat domain-containing protein 50","NP_079461.2//protein TANC2 [Homo sapiens]","3//A2MP1"]
[65986,9242,1.12,0.66,-0.762960802699151,0.00115558563624309,"*",0.000327346,"ZBTB10","GO:0005654//nucleoplasm","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K10497//zinc finger and BTB domain-containing protein 10","NP_001099009.1//zinc finger and BTB domain-containing protein 10 isoform a [Homo sapiens];NP_076418.3//zinc finger and BTB domain-containing protein 10 isoform b [Homo sapiens];XP_021521595.1//LOW QUALITY PROTEIN: zinc finger and BTB domain-containing protein 10 [Aotus nancymaae]","1//3;4;2//1"]
[7011,10554,2.15,1.27,-0.759508162817294,{"v":6.86320369964664e-08,"d":"6.86E-08"},"*",{"v":9.72724e-09,"d":"9.73E-09"},"TEP1","GO:0000781//chromosome, telomeric region;GO:0016363//nuclear matrix;GO:0005737//cytoplasm;GO:0071013//catalytic step 2 spliceosome;GO:0030529//intracellular ribonucleoprotein complex;GO:0005697//telomerase holoenzyme complex;GO:0005682//U5 snRNP;GO:0071011//precatalytic spliceosome","GO:0003723//RNA binding;GO:0005524//ATP binding;GO:0002039//p53 binding;GO:0003720//telomerase activity;GO:0019899//enzyme binding;GO:0070034//telomerase RNA binding","GO:0000722//telomere maintenance via recombination;GO:0008380//RNA splicing","K11127//telomerase protein component 1","NP_009041.2//telomerase protein component 1 isoform 1 [Homo sapiens];NP_001305964.1//telomerase protein component 1 isoform 2 [Homo sapiens]","4;1//3"]
[7248,8572,4.13,2.44,-0.759260633856559,{"v":5.09749459459459e-11,"d":"5.10E-11"},"*",{"v":4.959e-12,"d":"4.96E-12"},"TSC1","GO:0016020//membrane;GO:0005856//cytoskeleton;GO:0033596//TSC1-TSC2 complex;GO:0005634//nucleus;GO:0005938//cell cortex;GO:0030027//lamellipodium;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0005884//actin filament;GO:0030426//growth cone;GO:0043234//protein complex;GO:0005829//cytosol;GO:0005811//lipid droplet;GO:0005886//plasma membrane","GO:0047485//protein N-terminus binding;GO:0051087//chaperone binding;GO:0032794//GTPase activating protein binding","GO:0045859//regulation of protein kinase activity;GO:0001952//regulation of cell-matrix adhesion;GO:0043666//regulation of phosphoprotein phosphatase activity;GO:0021766//hippocampus development;GO:0008344//adult locomotory behavior;GO:0032956//regulation of actin cytoskeleton organization;GO:0051893//regulation of focal adhesion assembly;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0017148//negative regulation of translation;GO:0021987//cerebral cortex development;GO:0008285//negative regulation of cell proliferation;GO:0006813//potassium ion transport;GO:0090630//activation of GTPase activity;GO:0055007//cardiac muscle cell differentiation;GO:0090650//cellular response to oxygen-glucose deprivation;GO:1903204//negative regulation of oxidative stress-induced neuron death;GO:0051894//positive regulation of focal adhesion assembly;GO:0002250//adaptive immune response;GO:0045792//negative regulation of cell size;GO:0007160//cell-matrix adhesion;GO:0046323//glucose import;GO:0051726//regulation of cell cycle;GO:0001843//neural tube closure;GO:0034260//negative regulation of GTPase activity;GO:1901214//regulation of neuron death;GO:0032007//negative regulation of TOR signaling;GO:0001822//kidney development;GO:0007050//cell cycle arrest;GO:0010977//negative regulation of neuron projection development;GO:0050808//synapse organization;GO:0051492//regulation of stress fiber assembly;GO:0043379//memory T cell differentiation;GO:0042552//myelination;GO:0051291//protein heterooligomerization;GO:0006407//rRNA export from nucleus;GO:0032868//response to insulin;GO:0030030//cell projection organization;GO:0006417//regulation of translation;GO:0061024//membrane organization;GO:0043087//regulation of GTPase activity;GO:0016239//positive regulation of macroautophagy;GO:0051496//positive regulation of stress fiber assembly;GO:0050821//protein stabilization;GO:0016242//negative regulation of macroautophagy","K07206//tuberous sclerosis 1","NP_001155899.1//hamartin isoform 4 [Homo sapiens];NP_001155898.1//hamartin isoform 3 [Homo sapiens];NP_000359.1//hamartin isoform 1 [Homo sapiens]","4;1//3"]
[79955,2870,1.3,0.77,-0.755581272333553,0.205705096658517,"*",0.1106048,"PDZD7","GO:0005929//cilium;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0002141//stereocilia ankle link;GO:1990696//USH2 complex","GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity","GO:0045184//establishment of protein localization;GO:0060088//auditory receptor cell stereocilium organization;GO:0050910//detection of mechanical stimulus involved in sensory perception of sound","K21882//PDZ domain-containing protein 7","NP_079171.1//PDZ domain-containing protein 7 isoform 2 [Homo sapiens];NP_001182192.1//PDZ domain-containing protein 7 isoform 1 [Homo sapiens];NP_001337973.1//PDZ domain-containing protein 7 isoform 3 [Homo sapiens]","1//3;4"]
[54578,1871,3.93,2.33,-0.754199357604326,0.0096021327388535,"*",0.0033031,"UGT1A6","GO:0070062//extracellular exosome;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0046982//protein heterodimerization activity;GO:0015020//glucuronosyltransferase activity;GO:0042803//protein homodimerization activity;GO:0019899//enzyme binding","GO:2001030//negative regulation of cellular glucuronidation;GO:0008152//metabolic process;GO:0052697//xenobiotic glucuronidation;GO:0006805//xenobiotic metabolic process;GO:0052695//cellular glucuronidation;GO:0045922//negative regulation of fatty acid metabolic process;GO:1904224//negative regulation of glucuronosyltransferase activity;GO:0052696//flavonoid glucuronidation","K00699//glucuronosyltransferase [EC:2.4.1.17]","NP_001063.2//UDP-glucuronosyltransferase 1-6 isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[114335,732,0.64,0.38,-0.752072486556414,0.631085667338397,"*",0.50972,"CGB1","GO:0005576//extracellular region","GO:0005179//hormone activity","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0016486//peptide hormone processing;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0007292//female gamete generation;GO:0006915//apoptotic process","K10045//chorionic gonadotropin, beta polypeptide","EAW52435.1//chorionic gonadotropin, beta polypeptide 2 [Homo sapiens]","1//3"]
[348093,2023,14.96,8.89,-0.750854851057867,{"v":3.52374916675379e-09,"d":"3.52E-09"},"*",{"v":4.21994e-10,"d":"4.22E-10"},"RBPMS2","GO:0005737//cytoplasm","GO:0003729//mRNA binding;GO:0042803//protein homodimerization activity","GO:0030514//negative regulation of BMP signaling pathway;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0051151//negative regulation of smooth muscle cell differentiation;GO:0048557//embryonic digestive tract morphogenesis","K02728//20S proteasome subunit alpha 3 [EC:3.4.25.1];K21245//transcription factor SPT20 homolog","NP_919248.1//RNA-binding protein with multiple splicing 2 [Homo sapiens]","2//1"]
[6873,5049,7.8,4.64,-0.749349318622039,{"v":8.00547863414634e-12,"d":"8.01E-12"},"*",{"v":7.1916e-13,"d":"7.19E-13"},"TAF2","GO:0033276//transcription factor TFTC complex;GO:0005654//nucleoplasm;GO:0005669//transcription factor TFIID complex","GO:0003682//chromatin binding;GO:0043565//sequence-specific DNA binding;GO:0001129//RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly;GO:0044212//transcription regulatory region DNA binding","GO:0006368//transcription elongation from RNA polymerase II promoter;GO:1901796//regulation of signal transduction by p53 class mediator;GO:0014070//response to organic cyclic compound;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0000086//G2/M transition of mitotic cell cycle;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter","K03128//transcription initiation factor TFIID subunit 2","NP_003175.1//transcription initiation factor TFIID subunit 2 [Homo sapiens]","3//A2MP1"]
[7508,3654,12.08,7.19,-0.748556778885781,{"v":2.05057615306285E-13,"d":"2.05E-13"},"*",{"v":1.613606e-14,"d":"1.61E-14"},"XPC","GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000111//nucleotide-excision repair factor 2 complex;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0071942//XPC complex","GO:0003697//single-stranded DNA binding;GO:0000405//bubble DNA binding;GO:0003684//damaged DNA binding;GO:0000404//heteroduplex DNA loop binding","GO:0042493//response to drug;GO:0010996//response to auditory stimulus;GO:0000715//nucleotide-excision repair, DNA damage recognition;GO:0006281//DNA repair;GO:0006298//mismatch repair;GO:0000717//nucleotide-excision repair, DNA duplex unwinding;GO:0010224//response to UV-B;GO:0070911//global genome nucleotide-excision repair;GO:0006289//nucleotide-excision repair;GO:0006294//nucleotide-excision repair, preincision complex assembly;GO:1901990//regulation of mitotic cell cycle phase transition;GO:0031573//intra-S DNA damage checkpoint;GO:0070914//UV-damage excision repair","K10838//xeroderma pigmentosum group C-complementing protein","NP_001341658.1//DNA repair protein complementing XP-C cells isoform 5 [Homo sapiens];NP_001341659.1//DNA repair protein complementing XP-C cells isoform 6 [Homo sapiens];NP_004619.3//DNA repair protein complementing XP-C cells [Homo sapiens];NP_001341656.1//DNA repair protein complementing XP-C cells isoform 4 [Homo sapiens]","4;1//3"]
[10743,7668,21.56,12.85,-0.746588818671265,{"v":7.14302765555555e-47,"d":"7.14E-47"},"*",{"v":1.126858e-48,"d":"1.13E-48"},"RAI1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion","GO:0046872//metal ion binding;GO:0035326//enhancer binding;GO:0044212//transcription regulatory region DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0040015//negative regulation of multicellular organism growth;GO:0032922//circadian regulation of gene expression;GO:0001501//skeletal system development;GO:0045893//positive regulation of transcription, DNA-templated","K19749//retinoic acid-induced protein 1","NP_109590.3//retinoic acid-induced protein 1 [Homo sapiens]","3//A2MP1"]
[9282,6768,13.04,7.78,-0.745101809244885,{"v":3.57257638690909e-25,"d":"3.57E-25"},"*",{"v":1.230072E-26,"d":"1.23E-26"},"MED14","GO:0016020//membrane;GO:0070847//core mediator complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016592//mediator complex","GO:0042809//vitamin D receptor binding;GO:0003713//transcription coactivator activity;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0004872//receptor activity;GO:0003712//transcription cofactor activity;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0019827//stem cell population maintenance;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0030521//androgen receptor signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated","K15156//mediator of RNA polymerase II transcription subunit 14","NP_004220.2//mediator of RNA polymerase II transcription subunit 14 [Homo sapiens]","3//A2MP1"]
[158880,4410,0.72,0.43,-0.743660246740214,0.100979890159325,"*",0.0472154,"USP51","GO:0005694//chromosome","GO:0042393//histone binding;GO:0004843//thiol-dependent ubiquitin-specific protease activity;GO:0003682//chromatin binding;GO:0008270//zinc ion binding","GO:0016578//histone deubiquitination;GO:0006281//DNA repair;GO:2001032//regulation of double-strand break repair via nonhomologous end joining;GO:2001020//regulation of response to DNA damage stimulus;GO:0010569//regulation of double-strand break repair via homologous recombination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination;GO:0010564//regulation of cell cycle process","K11366//ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12]","NP_958443.1//ubiquitin carboxyl-terminal hydrolase 51 [Homo sapiens]","3//A2MP1"]
[201164,2591,8.75,5.24,-0.739716205182241,{"v":5.4892301142182e-07,"d":"5.49E-07"},"*",{"v":8.7249e-08,"d":"8.72E-08"},"PLD6","GO:0016021//integral component of membrane;GO:0005741//mitochondrial outer membrane","GO:0046872//metal ion binding;GO:0035755//cardiolipin hydrolase activity;GO:0042803//protein homodimerization activity;GO:0004519//endonuclease activity","GO:0008053//mitochondrial fusion;GO:0016042//lipid catabolic process;GO:0010636//positive regulation of mitochondrial fusion;GO:0051321//meiotic cell cycle;GO:0043046//DNA methylation involved in gamete generation;GO:0030719//P granule organization;GO:0007286//spermatid development;GO:0034587//piRNA metabolic process;GO:0006654//phosphatidic acid biosynthetic process","K16862//mitochondrial cardiolipin hydrolase [EC:3.1.4.-]","XP_003808818.1//PREDICTED: mitochondrial cardiolipin hydrolase [Pan paniscus]","3//A2MP1"]
[79807,4098,5.82,3.49,-0.737792116698632,{"v":1.28272454042918E-7,"d":"1.28E-07"},"*",{"v":1.871008e-08,"d":"1.87E-08"},"GSTCD","GO:0070062//extracellular exosome;GO:0005737//cytoplasm","GO:0016740//transferase activity","NA","K15696//RING finger protein 113B;K17985//activating molecule in BECN1-regulated autophagy protein 1;K06824//nephronectin","NP_001026890.2//glutathione S-transferase C-terminal domain-containing protein isoform 1 [Homo sapiens];NP_079027.2//glutathione S-transferase C-terminal domain-containing protein isoform 2 [Homo sapiens]","3//A2MP1"]
[8174,1285,0.1,0.06,-0.736965594166206,0.733487956900975,"*",0.626454,"MADCAM1","GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0098640//integrin binding involved in cell-matrix adhesion","GO:0043113//receptor clustering;GO:0007165//signal transduction;GO:0050901//leukocyte tethering or rolling;GO:0007568//aging;GO:0007160//cell-matrix adhesion;GO:0007155//cell adhesion;GO:0030198//extracellular matrix organization;GO:0034113//heterotypic cell-cell adhesion;GO:0006955//immune response;GO:0007229//integrin-mediated signaling pathway;GO:0002687//positive regulation of leukocyte migration;GO:0050776//regulation of immune response","K06779//mucosal vascular addressin cell adhesion molecule 1","NP_570116.2//mucosal addressin cell adhesion molecule 1 isoform a precursor [Homo sapiens];NP_570118.1//mucosal addressin cell adhesion molecule 1 isoform b precursor [Homo sapiens]","2//1"]
[55521,4240,0.15,0.09,-0.736965594166206,0.582628472521828,"*",0.426084,"TRIM36","GO:0070062//extracellular exosome;GO:0005856//cytoskeleton;GO:0005829//cytosol;GO:0001669//acrosomal vesicle","GO:0008270//zinc ion binding;GO:0004842//ubiquitin-protein transferase activity","GO:0007340//acrosome reaction;GO:0051726//regulation of cell cycle;GO:0000209//protein polyubiquitination","K12013//tripartite motif-containing protein 36 [EC:2.3.2.27];K09291//nucleoprotein TPR","NP_001287688.1//E3 ubiquitin-protein ligase TRIM36 isoform 5 [Homo sapiens];NP_001017398.1//E3 ubiquitin-protein ligase TRIM36 isoform 3 [Homo sapiens];NP_061170.2//E3 ubiquitin-protein ligase TRIM36 isoform 1 [Homo sapiens];KFD45978.1//hypothetical protein M513_13134 [Trichuris suis]","1//3;3//A2MP1"]
[56999,7251,0.85,0.51,-0.736965594166206,0.0157218772622528,"*",0.00572322,"ADAMTS9","GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0009986//cell surface;GO:0005578//proteinaceous extracellular matrix","GO:0008237//metallopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding","GO:0006508//proteolysis;GO:0007275//multicellular organism development;GO:0006516//glycoprotein catabolic process;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0045636//positive regulation of melanocyte differentiation","K08624//a disintegrin and metalloproteinase with thrombospondin motifs 9 [EC:3.4.24.-]","NP_891550.1//A disintegrin and metalloproteinase with thrombospondin motifs 9 isoform 1 preproprotein [Homo sapiens];NP_001305710.1//A disintegrin and metalloproteinase with thrombospondin motifs 9 isoform 4 precursor [Homo sapiens]","1//3"]
[2650,5528,0.4,0.24,-0.736965594166206,0.145816370339088,"*",0.0734924,"GCNT1","GO:0016020//membrane;GO:0005615//extracellular space;GO:0016021//integral component of membrane;GO:0031985//Golgi cisterna;GO:0005802//trans-Golgi network;GO:0000139//Golgi membrane","GO:0008375//acetylglucosaminyltransferase activity;GO:0003829//beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity","GO:0048729//tissue morphogenesis;GO:0009101//glycoprotein biosynthetic process;GO:0060352//cell adhesion molecule production;GO:0032868//response to insulin;GO:0060993//kidney morphogenesis;GO:0050901//leukocyte tethering or rolling;GO:0016266//O-glycan processing","K00727//beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase [EC:2.4.1.102]","NP_001481.2//beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase [Homo sapiens]","4;1//3"]
[51761,9355,0.05,0.03,-0.736965594166206,0.498508323513465,"*",0.345342,"ATP8A2","GO:0005768//endosome;GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0000287//magnesium ion binding;GO:0005524//ATP binding;GO:0004012//phospholipid-translocating ATPase activity","GO:0061092//positive regulation of phospholipid translocation;GO:0043588//skin development;GO:0010996//response to auditory stimulus;GO:0050908//detection of light stimulus involved in visual perception;GO:0050884//neuromuscular process controlling posture;GO:0042755//eating behavior;GO:0010976//positive regulation of neuron projection development;GO:0003011//involuntary skeletal muscle contraction;GO:0010842//retina layer formation;GO:0048666//neuron development;GO:0007409//axonogenesis;GO:0007568//aging;GO:0042472//inner ear morphogenesis;GO:0040018//positive regulation of multicellular organism growth;GO:0060052//neurofilament cytoskeleton organization","K14802//phospholipid-transporting ATPase [EC:3.6.3.1]","XP_006159595.1//PREDICTED: phospholipid-transporting ATPase IB isoform X1 [Tupaia chinensis];XP_012664962.1//PREDICTED: phospholipid-transporting ATPase IB isoform X1 [Otolemur garnettii]","1//3;5"]
[23291,4510,12.74,7.65,-0.735833624676286,{"v":1.30490723015075e-16,"d":"1.30E-16"},"*",{"v":8.1281e-18,"d":"8.13E-18"},"FBXW11","NA","NA","NA","K03362//F-box and WD-40 domain protein 1/11","XP_006978940.2//PREDICTED: F-box/WD repeat-containing protein 11 isoform X3 [Peromyscus maniculatus bairdii];XP_015853092.1//PREDICTED: F-box/WD repeat-containing protein 11 isoform X2 [Peromyscus maniculatus bairdii];XP_006978941.2//PREDICTED: F-box/WD repeat-containing protein 11 isoform X4 [Peromyscus maniculatus bairdii]","2//1"]
[134147,4047,8.13,4.89,-0.733420887122794,{"v":1.26779434675468e-09,"d":"1.27E-09"},"*",{"v":1.442876e-10,"d":"1.44E-10"},"CMBL","GO:0070062//extracellular exosome;GO:0005829//cytosol","GO:0016787//hydrolase activity","GO:0006805//xenobiotic metabolic process","K01061//carboxymethylenebutenolidase [EC:3.1.1.45]","NP_620164.1//carboxymethylenebutenolidase homolog [Homo sapiens]","3//A2MP1"]
[11196,7306,8.92,5.37,-0.732121621934892,{"v":2.53193762018349e-18,"d":"2.53E-18"},"*",{"v":1.382152e-19,"d":"1.38E-19"},"SEC23IP","GO:0043231//intracellular membrane-bounded organelle;GO:0005783//endoplasmic reticulum;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005737//cytoplasm;GO:0000139//Golgi membrane;GO:0030134//COPII-coated ER to Golgi transport vesicle;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0012507//ER to Golgi transport vesicle membrane","GO:0004620//phospholipase activity;GO:0003723//RNA binding;GO:0046872//metal ion binding","GO:0006886//intracellular protein transport;GO:0048208//COPII vesicle coating;GO:0007030//Golgi organization;GO:0006888//ER to Golgi vesicle-mediated transport","K16545//phospholipase DDHD2 [EC:3.1.1.-]","NP_009121.1//SEC23-interacting protein [Homo sapiens]","3//A2MP1"]
[1831,2087,6.7,4.04,-0.72980580259334,2.1514971052094E-4,"*",{"v":5.27436e-05,"d":"5.27E-05"},"TSC22D3","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0003700//DNA binding transcription factor activity;GO:0043426//MRF binding","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006970//response to osmotic stress;GO:0006355//regulation of transcription, DNA-templated;GO:0034220//ion transmembrane transport;GO:0070236//negative regulation of activation-induced cell death of T cells;GO:0048642//negative regulation of skeletal muscle tissue development","K15033//peptidyl-tRNA hydrolase ICT1 [EC:3.1.1.29]","NP_004080.2//TSC22 domain family protein 3 isoform 2 [Homo sapiens];EAX02707.1//TSC22 domain family, member 3, isoform CRA_b, partial [Homo sapiens];XP_007990698.1//PREDICTED: TSC22 domain family protein 3 isoform X1 [Chlorocebus sabaeus]","1//3;3//A2MP1;2//1"]
[1032,1175,3.73,2.25,-0.729250629038201,0.0438582701037126,"*",0.0182665,"CDKN2D","GO:0097129//cyclin D2-CDK4 complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0004861//cyclin-dependent protein serine/threonine kinase inhibitor activity;GO:0016301//kinase activity;GO:0019901//protein kinase binding","GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0030308//negative regulation of cell growth;GO:1902807//negative regulation of cell cycle G1/S phase transition;GO:0009411//response to UV;GO:0033280//response to vitamin D;GO:0032526//response to retinoic acid;GO:0042326//negative regulation of phosphorylation;GO:0007050//cell cycle arrest;GO:1902230//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage;GO:0000731//DNA synthesis involved in DNA repair;GO:0007605//sensory perception of sound;GO:0000082//G1/S transition of mitotic cell cycle;GO:0048102//autophagic cell death;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0008285//negative regulation of cell proliferation","K06623//cyclin-dependent kinase inhibitor 2D","NP_001791.1//cyclin-dependent kinase 4 inhibitor D [Homo sapiens]","3//A2MP1;2//1"]
[399687,7183,11.59,7,-0.727453739174143,{"v":6.38721764435946e-26,"d":"6.39E-26"},"*",{"v":2.09122e-27,"d":"2.09E-27"},"MYO18A","GO:0016020//membrane;GO:0009986//cell surface;GO:0016459//myosin complex;GO:0042641//actomyosin;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005802//trans-Golgi network;GO:0000139//Golgi membrane","GO:0043531//ADP binding;GO:0051015//actin filament binding;GO:0003723//RNA binding;GO:0003677//DNA binding;GO:0005524//ATP binding;GO:0003774//motor activity;GO:0008094//DNA-dependent ATPase activity","GO:1903028//positive regulation of opsonization;GO:0016477//cell migration;GO:0031032//actomyosin structure organization;GO:0043030//regulation of macrophage activation;GO:0043066//negative regulation of apoptotic process;GO:0007030//Golgi organization;GO:0006259//DNA metabolic process;GO:0050714//positive regulation of protein secretion;GO:0048194//Golgi vesicle budding;GO:0090164//asymmetric Golgi ribbon formation;GO:0090161//Golgi ribbon formation","K10362//myosin XVIII","NP_001333696.1//unconventional myosin-XVIIIa isoform e [Homo sapiens];NP_001333695.1//unconventional myosin-XVIIIa isoform d [Homo sapiens];BAD66838.1//KIAA0216 splice variant 2, partial [Homo sapiens];NP_001333694.1//unconventional myosin-XVIIIa isoform c [Homo sapiens];NP_510880.2//unconventional myosin-XVIIIa isoform a [Homo sapiens];NP_976063.1//unconventional myosin-XVIIIa isoform b [Homo sapiens]","1//3;3//A2MP1"]
[6197,7723,12.72,7.69,-0.726043167322529,{"v":9.97829855555555e-27,"d":"9.98E-27"},"*",{"v":3.14828E-28,"d":"3.15E-28"},"RPS6KA3","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005737//cytoplasm","GO:0000287//magnesium ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process;GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0016301//kinase activity;GO:0019901//protein kinase binding","GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007165//signal transduction;GO:0032496//response to lipopolysaccharide;GO:0030307//positive regulation of cell growth;GO:0043066//negative regulation of apoptotic process;GO:0035556//intracellular signal transduction;GO:0002224//toll-like receptor signaling pathway;GO:0007417//central nervous system development;GO:0043620//regulation of DNA-templated transcription in response to stress;GO:0043555//regulation of translation in response to stress;GO:0018105//peptidyl-serine phosphorylation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0001501//skeletal system development;GO:0007049//cell cycle;GO:0045597//positive regulation of cell differentiation","K04373//ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]","NP_004577.1//ribosomal protein S6 kinase alpha-3 [Homo sapiens]","2//1"]
[7832,2718,5.52,3.34,-0.724820164304117,{"v":9.14420813132695e-05,"d":"9.14E-05"},"*",{"v":2.09228e-05,"d":"2.09E-05"},"BTG2","GO:0070062//extracellular exosome;GO:0005829//cytosol","GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0009952//anterior/posterior pattern specification;GO:0014070//response to organic cyclic compound;GO:0051602//response to electrical stimulus;GO:0017148//negative regulation of translation;GO:0031175//neuron projection development;GO:0006974//cellular response to DNA damage stimulus;GO:0008285//negative regulation of cell proliferation;GO:0009612//response to mechanical stimulus;GO:0006281//DNA repair;GO:0043434//response to peptide hormone;GO:0021954//central nervous system neuron development;GO:0043524//negative regulation of neuron apoptotic process;GO:0006479//protein methylation;GO:0006351//transcription, DNA-templated;GO:0021542//dentate gyrus development;GO:2000178//negative regulation of neural precursor cell proliferation;GO:0035914//skeletal muscle cell differentiation;GO:0008306//associative learning;GO:0060213//positive regulation of nuclear-transcribed mRNA poly(A) tail shortening;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest","K14443//protein Tob/BTG","NP_006754.1//protein BTG2 [Homo sapiens]","2//1"]
[55342,6419,4.97,3.01,-0.723482364802584,{"v":3.58308081044386e-09,"d":"3.58E-09"},"*",{"v":4.29548e-10,"d":"4.30E-10"},"STRBP","GO:0005634//nucleus;GO:0015630//microtubule cytoskeleton;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0003677//DNA binding;GO:0003725//double-stranded RNA binding;GO:0003727//single-stranded RNA binding","GO:0007275//multicellular organism development;GO:0007286//spermatid development;GO:0007283//spermatogenesis;GO:0007638//mechanosensory behavior","K13200//spermatid perinuclear RNA-binding protein","NP_060857.2//spermatid perinuclear RNA-binding protein isoform 1 [Homo sapiens];EPQ16850.1//Spermatid perinuclear RNA-binding protein [Myotis brandtii]","1//3;4"]
[84441,7115,0.94,0.57,-0.721698837512896,0.0104930434413247,"*",3.64964E-3,"MAML2","NA","NA","NA","K06061//mastermind","XP_003910630.2//mastermind-like protein 2 isoform X1 [Papio anubis]","3//A2MP1"]
[6821,2564,9.62,5.84,-0.720068524890025,{"v":8.67938363506028e-06,"d":"8.68E-06"},"*",{"v":1.667524e-06,"d":"1.67E-06"},"SUOX","GO:0005759//mitochondrial matrix;GO:0005758//mitochondrial intermembrane space;GO:0005739//mitochondrion","GO:0043546//molybdopterin cofactor binding;GO:0020037//heme binding;GO:0008482//sulfite oxidase activity;GO:0030151//molybdenum ion binding;GO:0016491//oxidoreductase activity","GO:0042128//nitrate assimilation;GO:0070221//sulfide oxidation, using sulfide:quinone oxidoreductase","K00387//sulfite oxidase [EC:1.8.3.1]","XP_005269169.1//PREDICTED: sulfite oxidase, mitochondrial isoform X1 [Homo sapiens];XP_017801428.1//sulfite oxidase, mitochondrial isoform X1 [Papio anubis]","1//3;2//1"]
[5796,6104,4.94,3,-0.719548541088797,{"v":1.10245801509064E-8,"d":"1.10E-08"},"*",{"v":1.408612E-9,"d":"1.41E-09"},"PTPRK","GO:0043231//intracellular membrane-bounded organelle;GO:0030425//dendrite;GO:0030424//axon;GO:0031256//leading edge membrane;GO:0030054//cell junction;GO:0001750//photoreceptor outer segment;GO:0005912//adherens junction;GO:0043025//neuronal cell body;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0045295//gamma-catenin binding;GO:0005001//transmembrane receptor protein tyrosine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0019901//protein kinase binding;GO:0008013//beta-catenin binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0010839//negative regulation of keratinocyte proliferation;GO:0016477//cell migration;GO:0007165//signal transduction;GO:0045786//negative regulation of cell cycle;GO:0034614//cellular response to reactive oxygen species;GO:0030336//negative regulation of cell migration;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0034644//cellular response to UV;GO:0007155//cell adhesion;GO:0006470//protein dephosphorylation;GO:0031175//neuron projection development;GO:0034394//protein localization to cell surface;GO:0048041//focal adhesion assembly;GO:0008285//negative regulation of cell proliferation","K06776//receptor-type tyrosine-protein phosphatase kappa [EC:3.1.3.48]","NP_001278910.1//receptor-type tyrosine-protein phosphatase kappa isoform c precursor [Homo sapiens];XP_010341284.1//PREDICTED: receptor-type tyrosine-protein phosphatase kappa isoform X7 [Saimiri boliviensis boliviensis];NP_001278911.1//receptor-type tyrosine-protein phosphatase kappa isoform d precursor [Homo sapiens];NP_001129120.1//receptor-type tyrosine-protein phosphatase kappa isoform a precursor [Homo sapiens];XP_003353263.1//receptor-type tyrosine-protein phosphatase kappa isoform X15 [Sus scrofa];NP_001278912.1//receptor-type tyrosine-protein phosphatase kappa isoform e [Homo sapiens]","1//3;3//A2MP1;2//1"]
[54558,4976,0.51,0.31,-0.718229031584621,0.142487920539057,"*",0.0714848,"SPATA6","GO:0005576//extracellular region;GO:0097224//sperm connecting piece","GO:0032027//myosin light chain binding","GO:0030154//cell differentiation;GO:0007275//multicellular organism development;GO:0007283//spermatogenesis;GO:0044458//motile cilium assembly","NA","NP_001273167.1//spermatogenesis-associated protein 6 isoform 2 [Homo sapiens];NP_001273168.1//spermatogenesis-associated protein 6 isoform 3 [Homo sapiens];NP_061946.1//spermatogenesis-associated protein 6 isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[23035,8380,2.22,1.35,-0.717600269299275,{"v":1.14843309172259E-5,"d":"1.15E-05"},"*",{"v":2.24956e-06,"d":"2.25E-06"},"PHLPP2","GO:0005634//nucleus;GO:0001917//photoreceptor inner segment;GO:0005829//cytosol;GO:0042622//photoreceptor outer segment membrane;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0004722//protein serine/threonine phosphatase activity","GO:0007165//signal transduction;GO:0021766//hippocampus development;GO:0006470//protein dephosphorylation","K16340//PH domain and leucine-rich repeat-containing protein phosphatase [EC:3.1.3.16]","NP_001275932.1//PH domain leucine-rich repeat-containing protein phosphatase 2 isoform 2 [Homo sapiens];NP_055835.2//PH domain leucine-rich repeat-containing protein phosphatase 2 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[54361,3905,0.23,0.14,-0.716207033999409,0.382669878587859,"*",0.239534,"WNT4","GO:0005578//proteinaceous extracellular matrix","GO:0005102//receptor binding","GO:0007275//multicellular organism development;GO:0016055//Wnt signaling pathway","K00408//wingless-type MMTV integration site family, member 4","XP_524597.4//PREDICTED: protein Wnt-4 [Pan troglodytes]",4]
[5962,4433,25.73,15.67,-0.71544627726122,{"v":4.54472756788991e-30,"d":"4.54E-30"},"*",{"v":1.240454E-31,"d":"1.24E-31"},"RDX","GO:0005615//extracellular space;GO:0016324//apical plasma membrane;GO:0071944//cell periphery;GO:0030496//midbody;GO:0030864//cortical actin cytoskeleton;GO:0005913//cell-cell adherens junction;GO:0032420//stereocilium;GO:0005886//plasma membrane;GO:0005856//cytoskeleton;GO:0070062//extracellular exosome;GO:0030315//T-tubule;GO:0051286//cell tip;GO:0005925//focal adhesion;GO:0043209//myelin sheath;GO:0030027//lamellipodium;GO:0005902//microvillus;GO:0030175//filopodium;GO:0001726//ruffle;GO:0032154//cleavage furrow","GO:0003779//actin binding;GO:0003723//RNA binding;GO:0051018//protein kinase A binding;GO:0019904//protein domain specific binding;GO:0051117//ATPase binding;GO:0042803//protein homodimerization activity;GO:0045296//cadherin binding","GO:2000643//positive regulation of early endosome to late endosome transport;GO:0030335//positive regulation of cell migration;GO:1902966//positive regulation of protein localization to early endosome;GO:0032231//regulation of actin filament bundle assembly;GO:0045176//apical protein localization;GO:1900027//regulation of ruffle assembly;GO:1903392//negative regulation of adherens junction organization;GO:1902115//regulation of organelle assembly;GO:0036120//cellular response to platelet-derived growth factor stimulus;GO:0045184//establishment of protein localization;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle;GO:1903364//positive regulation of cellular protein catabolic process;GO:0032487//regulation of Rap protein signal transduction;GO:0072659//protein localization to plasma membrane;GO:0010737//protein kinase A signaling;GO:0008361//regulation of cell size;GO:0051016//barbed-end actin filament capping;GO:0008360//regulation of cell shape;GO:0010628//positive regulation of gene expression;GO:0030033//microvillus assembly;GO:0045792//negative regulation of cell size;GO:0034111//negative regulation of homotypic cell-cell adhesion;GO:0043087//regulation of GTPase activity;GO:0061028//establishment of endothelial barrier;GO:0034260//negative regulation of GTPase activity;GO:0097067//cellular response to thyroid hormone stimulus","K05762//radixin","XP_021526788.1//LOW QUALITY PROTEIN: radixin [Aotus nancymaae];NP_001247425.1//radixin isoform 5 [Homo sapiens];BAE40352.1//unnamed protein product, partial [Mus musculus];XP_003992383.1//PREDICTED: radixin isoform X1 [Felis catus];NP_001247423.1//radixin isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[84188,5292,11.37,6.93,-0.714304996755034,{"v":3.23711460766962E-16,"d":"3.24E-16"},"*",{"v":2.06094e-17,"d":"2.06E-17"},"FAR1","GO:0005779//integral component of peroxisomal membrane;GO:0005777//peroxisome","GO:0080019//fatty-acyl-CoA reductase (alcohol-forming) activity;GO:0102965//alcohol-forming fatty acyl-CoA reductase activity","GO:0008611//ether lipid biosynthetic process;GO:0035336//long-chain fatty-acyl-CoA metabolic process;GO:0010025//wax biosynthetic process;GO:0046474//glycerophospholipid biosynthetic process","K13356//alcohol-forming fatty acyl-CoA reductase [EC:1.2.1.84]","XP_012636183.1//fatty acyl-CoA reductase 1 isoform X4 [Microcebus murinus]",5]
[8916,4823,1,0.61,-0.713118852211838,0.013363162043387,"*",0.00478176,"HERC3","GO:0005829//cytosol;GO:0031410//cytoplasmic vesicle;GO:0005737//cytoplasm","GO:0061630//ubiquitin protein ligase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0016874//ligase activity","NA","K10614//E3 ubiquitin-protein ligase HERC3 [EC:2.3.2.26]","NP_001305434.1//probable E3 ubiquitin-protein ligase HERC3 isoform 3 [Homo sapiens];XP_004665475.1//PREDICTED: probable E3 ubiquitin-protein ligase HERC3 [Jaculus jaculus];XP_007184167.1//PREDICTED: probable E3 ubiquitin-protein ligase HERC3 isoform X4 [Balaenoptera acutorostrata scammoni]","1//3;2//1"]
[4090,6949,5.7,3.48,-0.711874613203376,{"v":4.41482723276983e-11,"d":"4.41E-11"},"*",{"v":4.25066e-12,"d":"4.25E-12"},"SMAD5","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005622//intracellular;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043234//protein complex;GO:0005667//transcription factor complex;GO:0016021//integral component of membrane;GO:0071141//SMAD protein complex","GO:0003677//DNA binding;GO:0005057//signal transducer activity, downstream of receptor;GO:0031625//ubiquitin protein ligase binding;GO:0017151//DEAD/H-box RNA helicase binding;GO:0046872//metal ion binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0030618//transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity;GO:0003700//DNA binding transcription factor activity","GO:0051216//cartilage development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0071407//cellular response to organic cyclic compound;GO:0009880//embryonic pattern specification;GO:0060048//cardiac muscle contraction;GO:0060348//bone development;GO:0007165//signal transduction;GO:0006468//protein phosphorylation;GO:0006351//transcription, DNA-templated;GO:0030509//BMP signaling pathway;GO:0045669//positive regulation of osteoblast differentiation;GO:0030218//erythrocyte differentiation;GO:1901522//positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus;GO:0060395//SMAD protein signal transduction;GO:0007281//germ cell development;GO:0002051//osteoblast fate commitment;GO:0001880//Mullerian duct regression;GO:0001657//ureteric bud development","K16790//mothers against decapentaplegic homolog 5","ELR59268.1//Mothers against decapentaplegic-like protein 5, partial [Bos mutus]","6;2//1"]
[55125,7995,2.52,1.54,-0.710493382805015,{"v":4.59055065487929e-06,"d":"4.59E-06"},"*",{"v":8.45174e-07,"d":"8.45E-07"},"CEP192","GO:0005814//centriole;GO:0000242//pericentriolar material;GO:0005829//cytosol;GO:0005813//centrosome","GO:0019902//phosphatase binding","GO:0010389//regulation of G2/M transition of mitotic cell cycle;GO:0097711//ciliary basal body-plasma membrane docking;GO:0051225//spindle assembly;GO:0051298//centrosome duplication;GO:0010923//negative regulation of phosphatase activity;GO:0000086//G2/M transition of mitotic cell cycle","K16725//centrosomal protein CEP192","NP_115518.3//centrosomal protein of 192 kDa [Homo sapiens]","3//A2MP1"]
[9805,5191,24.2,14.8,-0.709409871645645,{"v":2.96605956033994e-35,"d":"2.97E-35"},"*",{"v":6.55452e-37,"d":"6.55E-37"},"SCRN1","GO:0005634//nucleus;GO:0031965//nuclear membrane;GO:0005737//cytoplasm","GO:0016805//dipeptidase activity","GO:0006887//exocytosis","K14358//secernin","NP_055581.3//secernin-1 isoform a [Homo sapiens];NP_001138986.1//secernin-1 isoform b [Homo sapiens]","4;1//3"]
[56101,2457,0.67,0.41,-0.708537185839689,0.000746696408088235,"*",2.03432E-4,"PCDHGB5","GO:0070062//extracellular exosome;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005509//calcium ion binding","GO:0007399//nervous system development;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007267//cell-cell signaling","K16496//protocadherin gamma subfamily B","NP_061748.1//protocadherin gamma-B5 isoform 1 precursor [Homo sapiens];NP_115270.1//protocadherin gamma-B5 isoform 2 precursor [Homo sapiens]","1//3;2//1"]
[80329,2958,0.93,0.57,-0.70626879694329,0.0404534939650721,"*",0.01667624,"ULBP1","GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0015629//actin cytoskeleton;GO:0046658//anchored component of plasma membrane;GO:0005886//plasma membrane","GO:0046703//natural killer cell lectin-like receptor binding","GO:0030101//natural killer cell activation;GO:0042267//natural killer cell mediated cytotoxicity;GO:0016032//viral process;GO:0050776//regulation of immune response","K07986//UL16 binding protein","NP_079494.1//NKG2D ligand 1 isoform 1 precursor [Homo sapiens];KRX57831.1//LINE-1 reverse transcriptase -like protein [Trichinella sp. T6]","1//3;3//A2MP1"]
[83891,3331,2.72,1.67,-0.703758548776287,0.00384788083829956,"*",1.21261E-3,"SNX25","NA","NA","NA","K17887//sorting nexin-25","XP_005263324.1//PREDICTED: sorting nexin-25 isoform X6 [Homo sapiens]","1//3"]
[9779,6653,9.69,5.95,-0.703606997219775,{"v":1.39224797248255e-16,"d":"1.39E-16"},"*",{"v":8.74186e-18,"d":"8.74E-18"},"TBC1D5","GO:0043231//intracellular membrane-bounded organelle;GO:0010008//endosome membrane;GO:0030904//retromer complex;GO:1990316//Atg1/ULK1 kinase complex;GO:0030122//AP-2 adaptor complex;GO:0005622//intracellular;GO:0012505//endomembrane system;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0005776//autophagosome","GO:0035612//AP-2 adaptor complex binding;GO:1905394//retromer complex binding;GO:0017137//Rab GTPase binding;GO:0005096//GTPase activator activity","GO:0090630//activation of GTPase activity;GO:0042147//retrograde transport, endosome to Golgi;GO:0002092//positive regulation of receptor internalization;GO:0006886//intracellular protein transport;GO:0042594//response to starvation;GO:0006914//autophagy;GO:0031338//regulation of vesicle fusion;GO:0016236//macroautophagy","K18469//TBC1 domain family member 5","NP_001336010.1//TBC1 domain family member 5 isoform c [Homo sapiens];NP_001127853.1//TBC1 domain family member 5 isoform a [Homo sapiens];XP_009443270.1//PREDICTED: TBC1 domain family member 5 isoform X1 [Pan troglodytes];NP_055559.1//TBC1 domain family member 5 isoform b [Homo sapiens]","1//3;2//1"]
[659,12086,3.19,1.96,-0.702702769649661,{"v":1.76592472478632E-10,"d":"1.77E-10"},"*",{"v":1.810808e-11,"d":"1.81E-11"},"BMPR2","GO:0005654//nucleoplasm;GO:0005615//extracellular space;GO:0016324//apical plasma membrane;GO:0009925//basal plasma membrane;GO:0005901//caveola;GO:0009986//cell surface;GO:0005913//cell-cell adherens junction;GO:0005887//integral component of plasma membrane","GO:0098821//BMP receptor activity;GO:0005524//ATP binding;GO:0016362//activin receptor activity, type II;GO:0004702//signal transducer, downstream of receptor, with serine/threonine kinase activity;GO:0004675//transmembrane receptor protein serine/threonine kinase activity;GO:0036122//BMP binding","GO:0009952//anterior/posterior pattern specification;GO:0009267//cellular response to starvation;GO:0014916//regulation of lung blood pressure;GO:0002063//chondrocyte development;GO:0010595//positive regulation of endothelial cell migration;GO:0030513//positive regulation of BMP signaling pathway;GO:0060350//endochondral bone morphogenesis;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0001938//positive regulation of endothelial cell proliferation;GO:0001935//endothelial cell proliferation;GO:0030166//proteoglycan biosynthetic process;GO:0030308//negative regulation of cell growth;GO:0061036//positive regulation of cartilage development;GO:0003085//negative regulation of systemic arterial blood pressure;GO:0030509//BMP signaling pathway;GO:0045669//positive regulation of osteoblast differentiation;GO:0060840//artery development;GO:0006366//transcription from RNA polymerase II promoter;GO:2000279//negative regulation of DNA biosynthetic process;GO:0001974//blood vessel remodeling;GO:1902731//negative regulation of chondrocyte proliferation;GO:0030501//positive regulation of bone mineralization;GO:0060413//atrial septum morphogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0072577//endothelial cell apoptotic process","K04671//bone morphogenetic protein receptor type-2 [EC:2.7.11.30]","XP_003254004.1//PREDICTED: bone morphogenetic protein receptor type-2 [Nomascus leucogenys]",6]
[9695,6162,8.11,4.99,-0.700662098880012,{"v":3.50925391277259e-13,"d":"3.51E-13"},"*",{"v":2.82076E-14,"d":"2.82E-14"},"EDEM1","GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0044322//endoplasmic reticulum quality control compartment;GO:0000139//Golgi membrane","GO:0051787//misfolded protein binding;GO:0004571//mannosyl-oligosaccharide 1,2-alpha-mannosidase activity;GO:0005509//calcium ion binding","GO:0008152//metabolic process;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0006491//N-glycan processing;GO:0097466//ubiquitin-dependent glycoprotein ERAD pathway;GO:1904382//mannose trimming involved in glycoprotein ERAD pathway;GO:0036498//IRE1-mediated unfolded protein response;GO:1904154//positive regulation of retrograde protein transport, ER to cytosol;GO:0036510//trimming of terminal mannose on C branch","K10084//ER degradation enhancer, mannosidase alpha-like 1","NP_055489.1//ER degradation-enhancing alpha-mannosidase-like protein 1 [Homo sapiens]","2//1"]
[59341,3012,0.13,0.08,-0.700439718141092,0.63142824970919,"*",0.50972,"TRPV4","GO:0005929//cilium;GO:0009986//cell surface;GO:0016324//apical plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005912//adherens junction","GO:0051015//actin filament binding;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0015275//stretch-activated, cation-selective, calcium channel activity;GO:0042169//SH2 domain binding;GO:0019901//protein kinase binding;GO:0003779//actin binding;GO:0043014//alpha-tubulin binding;GO:0005034//osmosensor activity;GO:0005516//calmodulin binding","GO:0030103//vasopressin secretion;GO:0046330//positive regulation of JNK cascade;GO:0071642//positive regulation of macrophage inflammatory protein 1 alpha production;GO:0042593//glucose homeostasis;GO:0007015//actin filament organization;GO:0043117//positive regulation of vascular permeability;GO:2000778//positive regulation of interleukin-6 secretion;GO:0002024//diet induced thermogenesis;GO:0071651//positive regulation of chemokine (C-C motif) ligand 5 production;GO:0010628//positive regulation of gene expression;GO:0047484//regulation of response to osmotic stress;GO:0097497//blood vessel endothelial cell delamination;GO:1903759//signal transduction involved in regulation of aerobic respiration;GO:0007043//cell-cell junction assembly;GO:0071477//cellular hypotonic salinity response;GO:0010759//positive regulation of macrophage chemotaxis;GO:0050729//positive regulation of inflammatory response;GO:0071639//positive regulation of monocyte chemotactic protein-1 production;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0060351//cartilage development involved in endochondral bone morphogenesis;GO:2000340//positive regulation of chemokine (C-X-C motif) ligand 1 production;GO:0031532//actin cytoskeleton reorganization;GO:0032868//response to insulin;GO:0042538//hyperosmotic salinity response;GO:0050891//multicellular organismal water homeostasis;GO:0034605//cellular response to heat;GO:0007231//osmosensory signaling pathway;GO:0070509//calcium ion import;GO:2000507//positive regulation of energy homeostasis;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:1903444//negative regulation of brown fat cell differentiation;GO:0070374//positive regulation of ERK1 and ERK2 cascade","K04973//transient receptor potential cation channel subfamily V member 4","NP_001170902.1//transient receptor potential cation channel subfamily V member 4 isoform d [Homo sapiens];XP_011536935.2//PREDICTED: transient receptor potential cation channel subfamily V member 4 isoform X5 [Homo sapiens];XP_011536933.2//PREDICTED: transient receptor potential cation channel subfamily V member 4 isoform X2 [Homo sapiens];XP_011536934.2//PREDICTED: transient receptor potential cation channel subfamily V member 4 isoform X4 [Homo sapiens];XP_011536932.2//PREDICTED: transient receptor potential cation channel subfamily V member 4 isoform X1 [Homo sapiens]","1//3;4;2//1"]
[55251,3897,3.15,1.94,-0.699295176200151,0.000434174473357401,"*",1.129332E-4,"PCMTD2","NA","GO:0004719//protein-L-isoaspartate (D-aspartate) O-methyltransferase activity","NA","K00573//protein-L-isoaspartate(D-aspartate) O-methyltransferase [EC:2.1.1.77]","XP_008008332.1//PREDICTED: protein-L-isoaspartate O-methyltransferase domain-containing protein 2 [Chlorocebus sabaeus]","1//3;2//1"]
[5194,4524,8.53,5.26,-0.697482942025988,{"v":2.51895632095808e-10,"d":"2.52E-10"},"*",{"v":2.63344e-11,"d":"2.63E-11"},"PEX13","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005779//integral component of peroxisomal membrane;GO:0005777//peroxisome;GO:0005778//peroxisomal membrane","NA","GO:0021795//cerebral cortex cell migration;GO:0007626//locomotory behavior;GO:0001561//fatty acid alpha-oxidation;GO:0001764//neuron migration;GO:0016560//protein import into peroxisome matrix, docking;GO:0001967//suckling behavior;GO:0060152//microtubule-based peroxisome localization","K13344//peroxin-13","XP_012332678.1//peroxisome biogenesis factor 13 isoform X1 [Aotus nancymaae]","3//A2MP1"]
[80852,7721,0.6,0.37,-0.697437229979569,0.0452636563764424,"*",0.0189085,"GRIP2","GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0030159//receptor signaling complex scaffold activity","NA","K20251//glutamate receptor-interacting protein","NP_001073892.3//glutamate receptor-interacting protein 2 [Homo sapiens]","3//A2MP1"]
[22878,6283,3.82,2.36,-0.694785778673907,{"v":1.03492332012012E-6,"d":"1.03E-06"},"*",{"v":1.725952E-7,"d":"1.73E-07"},"TRAPPC8","GO:1990072//TRAPPIII protein complex;GO:0005829//cytosol;GO:0031410//cytoplasmic vesicle;GO:0000407//phagophore assembly site;GO:0030008//TRAPP complex","GO:0017112//Rab guanyl-nucleotide exchange factor activity","GO:0034497//protein localization to phagophore assembly site;GO:0030242//autophagy of peroxisome;GO:0044804//autophagy of nucleus;GO:0007030//Golgi organization;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0061024//membrane organization","K20305//trafficking protein particle complex subunit 8","NP_055754.2//trafficking protein particle complex subunit 8 [Homo sapiens]","3//A2MP1"]
[84775,4295,1.94,1.2,-0.693022246578609,0.00617402530472755,"*",2.03572E-3,"ZNF607","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","NP_001166148.1//zinc finger protein 607 isoform 2 [Homo sapiens];NP_116078.4//zinc finger protein 607 isoform 1 [Homo sapiens]","4;1//3"]
[113,5879,4.51,2.79,-0.692862311426193,{"v":2.45754656553998e-07,"d":"2.46E-07"},"*",{"v":3.73232E-8,"d":"3.73E-08"},"ADCY7","GO:0005622//intracellular;GO:0016021//integral component of membrane;GO:0008074//guanylate cyclase complex, soluble;GO:0005886//plasma membrane","GO:0016849//phosphorus-oxygen lyase activity;GO:0046872//metal ion binding;GO:0005524//ATP binding;GO:0000166//nucleotide binding;GO:0004016//adenylate cyclase activity;GO:0004383//guanylate cyclase activity","GO:0071361//cellular response to ethanol;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0071377//cellular response to glucagon stimulus;GO:0007165//signal transduction;GO:0060135//maternal process involved in female pregnancy;GO:0009190//cyclic nucleotide biosynthetic process;GO:0035556//intracellular signal transduction;GO:0006182//cGMP biosynthetic process;GO:0007190//activation of adenylate cyclase activity;GO:0034199//activation of protein kinase A activity;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0030819//positive regulation of cAMP biosynthetic process;GO:0003091//renal water homeostasis","K08047//adenylate cyclase 7 [EC:4.6.1.1]","NP_001105.1//adenylate cyclase type 7 isoform 1 [Homo sapiens];NP_001272986.1//adenylate cyclase type 7 isoform 2 [Homo sapiens]","1//3;4"]
[7112,3956,59.58,36.9,-0.691207307301772,{"v":7.59559850843373e-62,"d":"7.60E-62"},"*",{"v":7.89326E-64,"d":"7.89E-64"},"TMPO","GO:0016020//membrane;GO:0031965//nuclear membrane;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0000785//chromatin;GO:0005737//cytoplasm;GO:0016021//integral component of membrane;GO:0005637//nuclear inner membrane","GO:0003677//DNA binding;GO:0005521//lamin binding;GO:0045296//cadherin binding","GO:0006355//regulation of transcription, DNA-templated","K15710//E3 ubiquitin-protein ligase SHPRH [EC:3.6.4.- 2.3.2.27];K10592//E3 ubiquitin-protein ligase HUWE1 [EC:2.3.2.26];K12569//emerin;K10858//DNA mismatch repair protein PMS2;K04613//vomeronasal 2 receptor;K18624//macrophage erythroblast attacher;K15696//RING finger protein 113B;K17985//activating molecule in BECN1-regulated autophagy protein 1","BAD92534.1//Lamina-associated polypeptide 2, isoforms beta/gamma variant, partial [Homo sapiens];NP_001027454.1//thymopoietin isoform beta [Homo sapiens];NP_003267.1//thymopoietin isoform alpha [Homo sapiens];NP_001294904.1//thymopoietin isoform delta [Homo sapiens]","1//3;2//1"]
[6713,2989,54.48,33.75,-0.690839201186516,{"v":5.89534872786885e-40,"d":"5.90E-40"},"*",{"v":1.12563E-41,"d":"1.13E-41"},"SQLE","GO:0043231//intracellular membrane-bounded organelle;GO:0005783//endoplasmic reticulum;GO:0031090//organelle membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0050660//flavin adenine dinucleotide binding;GO:0004506//squalene monooxygenase activity","GO:0016126//sterol biosynthetic process;GO:0008203//cholesterol metabolic process;GO:0010033//response to organic substance;GO:0006725//cellular aromatic compound metabolic process;GO:0006695//cholesterol biosynthetic process;GO:0045540//regulation of cholesterol biosynthetic process","K00511//squalene monooxygenase [EC:1.14.14.17]","NP_003120.2//squalene monooxygenase [Homo sapiens]","3//A2MP1"]
[57561,4334,8.45,5.24,-0.689384529632096,{"v":9.09995927272727e-10,"d":"9.10E-10"},"*",{"v":1.021424E-10,"d":"1.02E-10"},"ARRDC3","GO:0005768//endosome;GO:0005764//lysosome;GO:0005886//plasma membrane;GO:0005769//early endosome","GO:0031699//beta-3 adrenergic receptor binding","GO:0001659//temperature homeostasis;GO:0090327//negative regulation of locomotion involved in locomotory behavior;GO:0043588//skin development;GO:0031651//negative regulation of heat generation;GO:0071879//positive regulation of adrenergic receptor signaling pathway;GO:0051443//positive regulation of ubiquitin-protein transferase activity;GO:0044252//negative regulation of multicellular organismal metabolic process;GO:0060613//fat pad development","K20910//thioredoxin-interacting protein","BAF84442.1//unnamed protein product [Homo sapiens];NP_065852.1//arrestin domain-containing protein 3 isoform a [Homo sapiens];BAC65781.1//mKIAA1376 protein, partial [Mus musculus];XP_003261654.1//PREDICTED: arrestin domain-containing protein 3 [Nomascus leucogenys]","1//3;3//A2MP1"]
[55388,4559,12.23,7.59,-0.68825261311192,{"v":3.61463809924306E-14,"d":"3.61E-14"},"*",{"v":2.6905e-15,"d":"2.69E-15"},"MCM10","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031298//replication fork protection complex;GO:0005730//nucleolus","GO:0003688//DNA replication origin binding;GO:0003697//single-stranded DNA binding;GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0019899//enzyme binding","GO:0008283//cell proliferation;GO:0006260//DNA replication;GO:0000082//G1/S transition of mitotic cell cycle;GO:0006270//DNA replication initiation;GO:0006974//cellular response to DNA damage stimulus","K10736//minichromosome maintenance protein 10","NP_877428.1//protein MCM10 homolog isoform 1 [Homo sapiens];NP_060988.3//protein MCM10 homolog isoform 2 [Homo sapiens]","4;2//1"]
[143279,3541,1.24,0.77,-0.687409769691974,0.0352026560855416,"*",0.01422078,"HECTD2","GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0061630//ubiquitin protein ligase activity;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity","GO:0000209//protein polyubiquitination","K12232//E3 ubiquitin-protein ligase HECTD2 [EC:2.3.2.26]","NP_775768.3//probable E3 ubiquitin-protein ligase HECTD2 isoform b [Homo sapiens];NP_001271203.1//probable E3 ubiquitin-protein ligase HECTD2 isoform c [Homo sapiens];NP_877497.3//probable E3 ubiquitin-protein ligase HECTD2 isoform a [Homo sapiens]","1//3;3//A2MP1;2//1;5"]
[66008,6527,5.28,3.28,-0.68684211474037,{"v":3.7153243189161e-09,"d":"3.72E-09"},"*",{"v":4.46332e-10,"d":"4.46E-10"},"TRAK2","GO:0005634//nucleus;GO:0032839//dendrite cytoplasm;GO:0044295//axonal growth cone;GO:0005737//cytoplasm;GO:0043025//neuronal cell body;GO:0005739//mitochondrion;GO:0005769//early endosome;GO:0005886//plasma membrane","GO:0030911//TPR domain binding;GO:0050811//GABA receptor binding;GO:0005102//receptor binding;GO:0019894//kinesin binding;GO:0019899//enzyme binding","GO:0006605//protein targeting;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006493//protein O-linked glycosylation;GO:0050771//negative regulation of axonogenesis;GO:0008333//endosome to lysosome transport;GO:0098972//anterograde dendritic transport of mitochondrion;GO:0048813//dendrite morphogenesis","K15374//trafficking kinesin-binding protein 2","NP_055864.2//trafficking kinesin-binding protein 2 [Homo sapiens]","2//1"]
[79666,2977,2.67,1.66,-0.685656500340629,0.00857751474420317,"*",0.00291788,"PLEKHF2","GO:0005783//endoplasmic reticulum;GO:0031901//early endosome membrane;GO:0030133//transport vesicle","GO:0046872//metal ion binding","GO:0015031//protein transport","K05724//FYVE, RhoGEF and PH domain containing 5/6","NP_078889.1//pleckstrin homology domain-containing family F member 2 [Homo sapiens]","3//A2MP1"]
[9819,4806,5.32,3.31,-0.684595028693972,{"v":5.94235307692308e-07,"d":"5.94E-07"},"*",{"v":9.4786e-08,"d":"9.48E-08"},"TSC22D2","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0003700//DNA binding transcription factor activity","GO:0006970//response to osmotic stress","K22023//mucin-6;K15033//peptidyl-tRNA hydrolase ICT1 [EC:3.1.1.29]","NP_001290193.1//TSC22 domain family protein 2 isoform 2 [Homo sapiens];NP_055594.1//TSC22 domain family protein 2 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[63926,3829,4.64,2.89,-0.683055312626893,{"v":3.14822327797409e-05,"d":"3.15E-05"},"*",{"v":6.69298e-06,"d":"6.69E-06"},"ANKEF1","NA","GO:0005509//calcium ion binding","NA","K10380//ankyrin;K15503//serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B","NP_071379.3//ankyrin repeat and EF-hand domain-containing protein 1 isoform 1 [Homo sapiens]","1//3;2//1;5"]
[5128,4379,3.88,2.42,-0.681049604912533,{"v":5.34068304604889E-5,"d":"5.34E-05"},"*",{"v":1.176194e-05,"d":"1.18E-05"},"CDK17","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity","GO:0006468//protein phosphorylation","K15595//cyclin-dependent kinase 17 [EC:2.7.11.22]","DAA29629.1//TPA: PCTAIRE protein kinase 2-like [Bos taurus]","4;2//1"]
[5578,8787,18.51,11.55,-0.680412043567154,{"v":2.32303050675241E-39,"d":"2.32E-39"},"*",{"v":4.52274e-41,"d":"4.52E-41"},"PRKCA","GO:0070062//extracellular exosome;GO:0005654//nucleoplasm;GO:0005783//endoplasmic reticulum;GO:0005622//intracellular;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0005829//cytosol;GO:0031966//mitochondrial membrane;GO:0005739//mitochondrion;GO:0005886//plasma membrane","GO:0046872//metal ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0035403//histone kinase activity (H3-T6 specific);GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0008270//zinc ion binding;GO:0004697//protein kinase C activity;GO:0019899//enzyme binding;GO:0004698//calcium-dependent protein kinase C activity","GO:0007077//mitotic nuclear envelope disassembly;GO:0030335//positive regulation of cell migration;GO:0097190//apoptotic signaling pathway;GO:0045785//positive regulation of cell adhesion;GO:0010595//positive regulation of endothelial cell migration;GO:0030168//platelet activation;GO:0035556//intracellular signal transduction;GO:0031666//positive regulation of lipopolysaccharide-mediated signaling pathway;GO:2000707//positive regulation of dense core granule biogenesis;GO:0090330//regulation of platelet aggregation;GO:0050796//regulation of insulin secretion;GO:0035408//histone H3-T6 phosphorylation;GO:0002159//desmosome assembly;GO:0070555//response to interleukin-1;GO:0007194//negative regulation of adenylate cyclase activity;GO:0043488//regulation of mRNA stability;GO:0045651//positive regulation of macrophage differentiation;GO:0001938//positive regulation of endothelial cell proliferation;GO:0045766//positive regulation of angiogenesis;GO:0007411//axon guidance;GO:0001525//angiogenesis;GO:0038128//ERBB2 signaling pathway;GO:0006468//protein phosphorylation;GO:0045931//positive regulation of mitotic cell cycle;GO:0034351//negative regulation of glial cell apoptotic process;GO:0010613//positive regulation of cardiac muscle hypertrophy;GO:0007155//cell adhesion;GO:0007190//activation of adenylate cyclase activity;GO:0018105//peptidyl-serine phosphorylation;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0043536//positive regulation of blood vessel endothelial cell migration","K02677//classical protein kinase C alpha type [EC:2.7.11.13]","NP_002728.1//protein kinase C alpha type [Homo sapiens]","2//1"]
[196,6247,5.62,3.51,-0.679099099916366,{"v":4.43768132436627E-9,"d":"4.44E-09"},"*",{"v":5.37e-10,"d":"5.37E-10"},"AHR","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0034753//nuclear aryl hydrocarbon receptor complex;GO:0034752//cytosolic aryl hydrocarbon receptor complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043234//protein complex;GO:0005667//transcription factor complex;GO:0034751//aryl hydrocarbon receptor complex","GO:0001223//transcription coactivator binding;GO:0003677//DNA binding;GO:0070888//E-box binding;GO:0046982//protein heterodimerization activity;GO:0044212//transcription regulatory region DNA binding;GO:0004879//nuclear receptor activity;GO:0046983//protein dimerization activity;GO:0051879//Hsp90 protein binding;GO:0017025//TBP-class protein binding;GO:0004874//aryl hydrocarbon receptor activity;GO:0035326//enhancer binding;GO:0008134//transcription factor binding;GO:0003700//DNA binding transcription factor activity;GO:0001094//TFIID-class transcription factor binding","GO:0010468//regulation of gene expression;GO:0006355//regulation of transcription, DNA-templated;GO:0001568//blood vessel development;GO:0009636//response to toxic substance;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0032922//circadian regulation of gene expression;GO:0045892//negative regulation of transcription, DNA-templated;GO:0030888//regulation of B cell proliferation;GO:0009410//response to xenobiotic stimulus;GO:0006805//xenobiotic metabolic process;GO:0006351//transcription, DNA-templated;GO:0006915//apoptotic process;GO:0006366//transcription from RNA polymerase II promoter;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007049//cell cycle","K09093//aryl hydrocarbon receptor","NP_001612.1//aryl hydrocarbon receptor [Homo sapiens]",4]
[11223,4668,0.32,0.2,-0.678071905112638,0.355984045519787,"*",0.21737,"MST1L","GO:0005615//extracellular space","GO:0004252//serine-type endopeptidase activity","NA","K05460//hepatocyte growth factor","NP_001258662.1//putative macrophage stimulating 1-like protein [Homo sapiens]","1//3"]
[83872,18212,0.08,0.05,-0.678071905112638,0.355911068060681,"*",0.21737,"HMCN1","GO:0070062//extracellular exosome;GO:0032154//cleavage furrow;GO:0005938//cell cortex;GO:0030054//cell junction;GO:0005604//basement membrane","GO:0005509//calcium ion binding","GO:0051301//cell division;GO:0050896//response to stimulus;GO:0007601//visual perception;GO:0007049//cell cycle","K17341//hemicentin","NP_114141.2//hemicentin-1 precursor [Homo sapiens]","2//1"]
[57335,5519,6.64,4.15,-0.678071905112637,{"v":2.48031417988292e-09,"d":"2.48E-09"},"*",{"v":2.91756E-10,"d":"2.92E-10"},"ZNF286A","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_019612967.1//PREDICTED: zinc finger protein 850 isoform X5 [Rhinolophus sinicus]","1//3;2//1"]
[10983,1724,41.19,25.77,-0.676601589008637,{"v":7.27167648780488e-18,"d":"7.27E-18"},"*",{"v":4.10608E-19,"d":"4.11E-19"},"CCNI","NA","NA","GO:0051726//regulation of cell cycle;GO:0007283//spermatogenesis","K10146//cyclin G2;K16939//septin 6/8/11","NP_001335064.1//cyclin-I isoform c [Homo sapiens];BAD93003.1//CCNI protein variant, partial [Homo sapiens];XP_021116662.1//cyclin-I isoform X3 [Heterocephalus glaber];NP_001335063.1//cyclin-I isoform b [Homo sapiens];NP_001335067.1//cyclin-I isoform f [Homo sapiens];NP_001335068.1//cyclin-I isoform g [Homo sapiens];NP_001335066.1//cyclin-I isoform e [Homo sapiens];NP_001335065.1//cyclin-I isoform d [Homo sapiens]","1//3;2//1"]
[221786,2548,2.38,1.49,-0.675649242845782,0.0239991647392438,"*",9.21866E-3,"FAM200A","GO:0005654//nucleoplasm;GO:0016021//integral component of membrane;GO:0005737//cytoplasm","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0003677//DNA binding","NA","K09228//KRAB domain-containing zinc finger protein;K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K02927//large subunit ribosomal protein L40e;K01064//wingless-type MMTV integration site family, member 9","NP_659802.1//protein FAM200A [Homo sapiens]","3//A2MP1"]
[157983,2786,0.75,0.47,-0.674229838818244,0.229640571826869,"*",0.1278736,"C9orf66","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein;K11447//histone demethylase [EC:1.14.11.-]","NP_689782.2//uncharacterized protein C9orf66 [Homo sapiens]","2//1"]
[81624,4768,5.04,3.16,-0.673499175322814,{"v":7.55421633205227E-7,"d":"7.55E-07"},"*",{"v":1.230504E-7,"d":"1.23E-07"},"DIAPH3","GO:0005634//nucleus;GO:0005829//cytosol","GO:0003779//actin binding;GO:0017048//Rho GTPase binding;GO:0045296//cadherin binding","GO:0030036//actin cytoskeleton organization;GO:0007283//spermatogenesis","K05745//diaphanous 3","NP_001245295.1//protein diaphanous homolog 3 isoform c [Homo sapiens];NP_001245298.1//protein diaphanous homolog 3 isoform f [Homo sapiens];EAW52069.1//diaphanous homolog 3 (Drosophila), isoform CRA_a [Homo sapiens];NP_001035982.1//protein diaphanous homolog 3 isoform a [Homo sapiens];NP_001245297.1//protein diaphanous homolog 3 isoform e [Homo sapiens];NP_001245296.1//protein diaphanous homolog 3 isoform d [Homo sapiens]","1//3;3//A2MP1"]
[26271,2143,11.24,7.05,-0.67294687293477,{"v":3.45434422083333e-06,"d":"3.45E-06"},"*",{"v":6.22794e-07,"d":"6.23E-07"},"FBXO5","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005819//spindle;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:1990948//ubiquitin ligase inhibitor activity;GO:0019901//protein kinase binding","GO:0007346//regulation of mitotic cell cycle;GO:0001556//oocyte maturation;GO:0007088//regulation of mitotic nuclear division;GO:0016050//vesicle organization;GO:0007057//spindle assembly involved in female meiosis I;GO:0045835//negative regulation of meiotic nuclear division;GO:1904668//positive regulation of ubiquitin protein ligase activity;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition;GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0051301//cell division;GO:0046785//microtubule polymerization;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle","K10292//F-box protein 5","NP_036309.1//F-box only protein 5 isoform a [Homo sapiens]","4;2//1"]
[7465,3359,8.97,5.63,-0.671973062839032,{"v":1.26170003475269E-7,"d":"1.26E-07"},"*",{"v":1.836392e-08,"d":"1.84E-08"},"WEE1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm","GO:0000287//magnesium ion binding;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity","GO:0000278//mitotic cell cycle;GO:0000226//microtubule cytoskeleton organization;GO:0030010//establishment of cell polarity;GO:0048812//neuron projection morphogenesis;GO:0051301//cell division;GO:0000082//G1/S transition of mitotic cell cycle;GO:0000086//G2/M transition of mitotic cell cycle;GO:0051726//regulation of cell cycle","K06632//wee1-like protein kinase [EC:2.7.11.1]","NP_003381.1//wee1-like protein kinase isoform 1 [Homo sapiens];XP_003254976.1//PREDICTED: wee1-like protein kinase isoform X3 [Nomascus leucogenys]","1//3;3//A2MP1"]
[5332,5425,2.74,1.72,-0.671767328258429,0.000260724020967742,"*",{"v":6.47648e-05,"d":"6.48E-05"},"PLCB4","GO:0005790//smooth endoplasmic reticulum;GO:0030425//dendrite;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005622//intracellular;GO:0014069//postsynaptic density","GO:0004435//phosphatidylinositol phospholipase C activity;GO:0005509//calcium ion binding;GO:0004871//signal transducer activity;GO:0004629//phospholipase C activity","GO:0016042//lipid catabolic process;GO:0043647//inositol phosphate metabolic process;GO:0035556//intracellular signal transduction","K05858//phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]","XP_016792922.1//PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X4 [Pan troglodytes];XP_009435053.2//PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X5 [Pan troglodytes];XP_016792923.1//PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X6 [Pan troglodytes]","1//3;3//A2MP1;2//1"]
[9581,6057,11.11,6.98,-0.67055987517944,{"v":3.72455713868613E-17,"d":"3.72E-17"},"*",{"v":2.23604E-18,"d":"2.24E-18"},"PREPL","GO:0005856//cytoskeleton;GO:0005794//Golgi apparatus;GO:0005829//cytosol","GO:0004252//serine-type endopeptidase activity;GO:0070008//serine-type exopeptidase activity","GO:2000300//regulation of synaptic vesicle exocytosis","K14210//solute carrier family 3 (neutral and basic amino acid transporter), member 1","NP_001035844.1//prolyl endopeptidase-like isoform 2 [Homo sapiens];NP_006027.2//prolyl endopeptidase-like isoform 1 [Homo sapiens];NP_001035845.1//prolyl endopeptidase-like isoform 3 [Homo sapiens]","4;1//3;2//1"]
[405,4875,8.91,5.6,-0.669998604576956,{"v":6.4731296464582e-11,"d":"6.47E-11"},"*",{"v":6.34994e-12,"d":"6.35E-12"},"ARNT","GO:0090575//RNA polymerase II transcription factor complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription factor complex;GO:0016604//nuclear body;GO:0005737//cytoplasm","GO:0003713//transcription coactivator activity;GO:0046982//protein heterodimerization activity;GO:0035326//enhancer binding;GO:0004874//aryl hydrocarbon receptor activity;GO:0008134//transcription factor binding;GO:0003700//DNA binding transcription factor activity;GO:0017162//aryl hydrocarbon receptor binding;GO:0046983//protein dimerization activity","GO:0046886//positive regulation of hormone biosynthetic process;GO:0010575//positive regulation of vascular endothelial growth factor production;GO:0033235//positive regulation of protein sumoylation;GO:0042789//mRNA transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0001892//embryonic placenta development;GO:0045821//positive regulation of glycolytic process;GO:0043619//regulation of transcription from RNA polymerase II promoter in response to oxidative stress;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0001938//positive regulation of endothelial cell proliferation;GO:0030154//cell differentiation;GO:0030949//positive regulation of vascular endothelial growth factor receptor signaling pathway;GO:0006805//xenobiotic metabolic process;GO:0006351//transcription, DNA-templated;GO:0001666//response to hypoxia;GO:0045648//positive regulation of erythrocyte differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter","K09097//aryl hydrocarbon receptor nuclear translocator","XP_008017478.1//PREDICTED: aryl hydrocarbon receptor nuclear translocator isoform X4 [Chlorocebus sabaeus];XP_008017477.1//PREDICTED: aryl hydrocarbon receptor nuclear translocator isoform X3 [Chlorocebus sabaeus];CAD38953.1//hypothetical protein, partial [Homo sapiens];NP_001337155.1//aryl hydrocarbon receptor nuclear translocator isoform 9 [Homo sapiens];NP_001337154.1//aryl hydrocarbon receptor nuclear translocator isoform 8 [Homo sapiens];XP_008017475.1//PREDICTED: aryl hydrocarbon receptor nuclear translocator isoform X1 [Chlorocebus sabaeus];XP_011793190.1//PREDICTED: aryl hydrocarbon receptor nuclear translocator isoform X2 [Colobus angolensis palliatus]","1//3;3//A2MP1;2//1"]
[130507,7969,3.21,2.02,-0.668218004370508,{"v":8.94936962833206e-07,"d":"8.95E-07"},"*",{"v":1.471206e-07,"d":"1.47E-07"},"UBR3","GO:0000151//ubiquitin ligase complex;GO:0016021//integral component of membrane;GO:0005737//cytoplasm","GO:0061630//ubiquitin protein ligase activity;GO:0008270//zinc ion binding;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity","GO:0007608//sensory perception of smell;GO:0071596//ubiquitin-dependent protein catabolic process via the N-end rule pathway;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0001967//suckling behavior;GO:0042048//olfactory behavior;GO:0009790//embryo development;GO:0001701//in utero embryonic development","K11978//E3 ubiquitin-protein ligase UBR3 [EC:2.3.2.27]","NP_742067.3//E3 ubiquitin-protein ligase UBR3 [Homo sapiens]","3//A2MP1"]
[253512,3691,2.92,1.84,-0.666262602823005,0.00342475003648026,"*",1.069618E-3,"SLC25A30","GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0005739//mitochondrion","GO:0022857//transmembrane transporter activity","GO:0006839//mitochondrial transport","K15106//solute carrier family 25 (mitochondrial carrier), member 14/30","NP_001010875.1//kidney mitochondrial carrier protein 1 isoform 1 [Homo sapiens];XP_011919750.1//PREDICTED: kidney mitochondrial carrier protein 1 isoform X1 [Cercocebus atys];NP_001273735.1//kidney mitochondrial carrier protein 1 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[9923,8521,4.14,2.61,-0.665580960929441,{"v":9.4248021490545e-10,"d":"9.42E-10"},"*",{"v":1.060836e-10,"d":"1.06E-10"},"ZBTB40","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003676//nucleic acid binding","GO:0030282//bone mineralization;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006974//cellular response to DNA damage stimulus","K10512//zinc finger and BTB domain-containing protein 40","NP_055685.3//zinc finger and BTB domain-containing protein 40 isoform a [Homo sapiens];NP_001317327.1//zinc finger and BTB domain-containing protein 40 isoform b [Homo sapiens]","1//3;3//A2MP1"]
[64375,4894,1.76,1.11,-0.665015752287191,0.00641906160954365,"*",0.00212214,"IKZF4","NA","GO:0003676//nucleic acid binding","NA","K09220//IKAROS family zinc finger protein","XP_020947441.1//zinc finger protein Eos isoform X1 [Sus scrofa];XP_009246156.1//PREDICTED: zinc finger protein Eos isoform X1 [Pongo abelii];XP_008976879.1//PREDICTED: zinc finger protein Eos isoform X5 [Pan paniscus]","1//3;3//A2MP1"]
[57462,6452,5.18,3.27,-0.663661462188471,{"v":1.73112128053435e-08,"d":"1.73E-08"},"*",{"v":2.27146e-09,"d":"2.27E-09"},"MYORG","GO:0031965//nuclear membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds","GO:0051897//positive regulation of protein kinase B signaling;GO:0005975//carbohydrate metabolic process;GO:0048741//skeletal muscle fiber development;GO:0043568//positive regulation of insulin-like growth factor receptor signaling pathway","K10955//mucin-2;K01187//alpha-glucosidase [EC:3.2.1.20];K05546//alpha 1,3-glucosidase [EC:3.2.1.84];K12316//lysosomal alpha-glucosidase [EC:3.2.1.20]","NP_065753.2//uncharacterized family 31 glucosidase KIAA1161 [Homo sapiens]",4]
[4146,3830,0.19,0.12,-0.662965012722429,0.612300480912828,"*",0.456868,"MATN1","GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix","GO:0005201//extracellular matrix structural constituent;GO:0005509//calcium ion binding","GO:0003429//growth plate cartilage chondrocyte morphogenesis;GO:0030500//regulation of bone mineralization;GO:0030198//extracellular matrix organization;GO:0006461//protein complex assembly","K19467//matrilin-3","NP_002370.1//cartilage matrix protein precursor [Homo sapiens]","3//A2MP1"]
[9748,7770,7.83,4.95,-0.661583782324069,{"v":1.65841403570191e-14,"d":"1.66E-14"},"*",{"v":1.198078e-15,"d":"1.20E-15"},"SLK","GO:0070062//extracellular exosome;GO:0031252//cell leading edge;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm","GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0045296//cadherin binding","GO:0023014//signal transduction by protein phosphorylation;GO:0007346//regulation of mitotic cell cycle;GO:0032147//activation of protein kinase activity;GO:0046777//protein autophosphorylation;GO:0006915//apoptotic process;GO:0051893//regulation of focal adhesion assembly;GO:0030334//regulation of cell migration;GO:0031098//stress-activated protein kinase signaling cascade;GO:0042981//regulation of apoptotic process;GO:0031122//cytoplasmic microtubule organization","K08836//STE20-like kinase [EC:2.7.11.1]","NP_055535.2//STE20-like serine/threonine-protein kinase isoform 1 [Homo sapiens];NP_001291672.1//STE20-like serine/threonine-protein kinase isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[92999,5524,3.46,2.19,-0.659841168035551,{"v":3.61944100204141e-05,"d":"3.62E-05"},"*",{"v":7.76954e-06,"d":"7.77E-06"},"ZBTB47","NA","NA","NA","K10518//zinc finger and BTB domain-containing protein 47","XP_008959737.2//PREDICTED: zinc finger and BTB domain-containing protein 47 [Pan paniscus]","3//A2MP1"]
[5774,6753,5.37,3.4,-0.659387341847711,{"v":7.10582134274194e-09,"d":"7.11E-09"},"*",{"v":8.82556e-10,"d":"8.83E-10"},"PTPN3","GO:0005856//cytoskeleton;GO:0009898//cytoplasmic side of plasma membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0001784//phosphotyrosine residue binding;GO:0017080//sodium channel regulator activity;GO:0008092//cytoskeletal protein binding;GO:0004725//protein tyrosine phosphatase activity;GO:0051117//ATPase binding","GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:2000649//regulation of sodium ion transmembrane transporter activity;GO:0045930//negative regulation of mitotic cell cycle;GO:0097421//liver regeneration;GO:0006470//protein dephosphorylation;GO:0051045//negative regulation of membrane protein ectodomain proteolysis;GO:0098902//regulation of membrane depolarization during action potential","K18027//tyrosine-protein phosphatase non-receptor type 3 [EC:3.1.3.48]","XP_007966658.1//PREDICTED: tyrosine-protein phosphatase non-receptor type 3 isoform X1 [Chlorocebus sabaeus];XP_011517190.1//PREDICTED: tyrosine-protein phosphatase non-receptor type 3 isoform X1 [Homo sapiens];XP_007966660.1//PREDICTED: tyrosine-protein phosphatase non-receptor type 3 isoform X2 [Chlorocebus sabaeus];XP_016870445.1//PREDICTED: tyrosine-protein phosphatase non-receptor type 3 isoform X7 [Homo sapiens];XP_006717265.1//PREDICTED: tyrosine-protein phosphatase non-receptor type 3 isoform X5 [Homo sapiens]","1//3;3//A2MP1"]
[647135,6810,4.72,2.99,-0.658641375163736,{"v":5.8722250415364e-08,"d":"5.87E-08"},"*",{"v":8.23082e-09,"d":"8.23E-09"},"SRGAP2B","GO:0005737//cytoplasm","GO:0048365//Rac GTPase binding;GO:0005096//GTPase activator activity","GO:0007399//nervous system development;GO:0007165//signal transduction;GO:0030336//negative regulation of cell migration","K07526//SLIT-ROBO Rho GTPase activating protein","NP_001258799.2//SLIT-ROBO Rho GTPase-activating protein 2B isoform 1 [Homo sapiens];XP_016857574.1//PREDICTED: SLIT-ROBO Rho GTPase-activating protein 2B isoform X1 [Homo sapiens]","1//3;2//1"]
[4082,4322,12.23,7.75,-0.658156188365787,{"v":1.77215532560528E-12,"d":"1.77E-12"},"*",{"v":1.512112E-13,"d":"1.51E-13"},"MARCKS","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005925//focal adhesion;GO:0005938//cell cortex;GO:0005813//centrosome;GO:0042585//germinal vesicle;GO:0015629//actin cytoskeleton;GO:0032432//actin filament bundle;GO:0005886//plasma membrane","GO:0051015//actin filament binding;GO:0005080//protein kinase C binding;GO:0016301//kinase activity;GO:0042802//identical protein binding;GO:0005516//calmodulin binding","GO:0051017//actin filament bundle assembly;GO:0051764//actin crosslink formation;GO:0051260//protein homooligomerization;GO:0050796//regulation of insulin secretion","K12561//myristoylated alanine-rich C-kinase substrate","NP_002347.5//myristoylated alanine-rich C-kinase substrate [Homo sapiens]",6]
[200424,11405,3.17,2.01,-0.657287338960479,{"v":9.06075752011923e-09,"d":"9.06E-09"},"*",{"v":1.141812E-9,"d":"1.14E-09"},"TET3","GO:0001940//male pronucleus;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0070579//methylcytosine dioxygenase activity","GO:0006493//protein O-linked glycosylation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0080182//histone H3-K4 trimethylation;GO:0080111//DNA demethylation;GO:0044727//DNA demethylation of male pronucleus","K13097//methylcytosine dioxygenase [EC:1.14.11.-]","NP_001274420.1//methylcytosine dioxygenase TET3 [Homo sapiens]","1//3"]
[55612,5167,6.99,4.44,-0.65473277902533,{"v":8.20030550898204e-09,"d":"8.20E-09"},"*",{"v":1.02876e-09,"d":"1.03E-09"},"FERMT1","GO:0005925//focal adhesion;GO:0005829//cytosol;GO:0030054//cell junction;GO:0032587//ruffle membrane;GO:0031941//filamentous actin","NA","GO:2001203//positive regulation of transforming growth factor-beta secretion;GO:0071711//basement membrane organization;GO:0001954//positive regulation of cell-matrix adhesion;GO:0043616//keratinocyte proliferation;GO:0010629//negative regulation of gene expression;GO:0090162//establishment of epithelial cell polarity;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0007155//cell adhesion;GO:2000647//negative regulation of stem cell proliferation;GO:0051886//negative regulation of timing of anagen;GO:0035414//negative regulation of catenin import into nucleus;GO:0051546//keratinocyte migration;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0033630//positive regulation of cell adhesion mediated by integrin","K17082//kindlin 1","NP_060141.3//fermitin family homolog 1 [Homo sapiens]",4]
[196415,1516,1.59,1.01,-0.654671472532561,0.209279601485091,"*",0.1129198,"C12orf77","NA","NA","NA","K01064//wingless-type MMTV integration site family, member 9","NP_001094809.2//putative uncharacterized protein C12orf77 [Homo sapiens]","2//1"]
[5922,5648,2.2,1.4,-0.652076696579693,1.3582356564952E-3,"*",0.000390108,"RASA2","GO:0005829//cytosol;GO:0005622//intracellular;GO:0031235//intrinsic component of the cytoplasmic side of the plasma membrane;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm","GO:0046872//metal ion binding;GO:0005096//GTPase activator activity","GO:0046580//negative regulation of Ras protein signal transduction;GO:0000165//MAPK cascade;GO:0007165//signal transduction;GO:0035556//intracellular signal transduction","K08053//Ras GTPase-activating protein 2","NP_001290174.1//ras GTPase-activating protein 2 isoform 2 [Homo sapiens];NP_001290175.1//ras GTPase-activating protein 2 isoform 1 [Homo sapiens];NP_006497.2//ras GTPase-activating protein 2 isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[339883,1836,0.22,0.14,-0.652076696579693,0.63128138316018,"*",0.50972,"C3orf35","GO:0016021//integral component of membrane","NA","NA","NA","XP_003945335.1//PREDICTED: LOW QUALITY PROTEIN: AP20 region protein 1 [Saimiri boliviensis boliviensis];XP_017363931.1//PREDICTED: LOW QUALITY PROTEIN: AP20 region protein 1 [Cebus capucinus imitator];NP_848029.2//AP20 region protein 1 isoform B [Homo sapiens]","1//3;2//1"]
[2646,2197,0.11,0.07,-0.652076696579693,0.781374807266534,"*",0.689316,"GCKR","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005737//cytoplasm","GO:0030246//carbohydrate binding;GO:0019904//protein domain specific binding;GO:0097367//carbohydrate derivative binding;GO:0016301//kinase activity;GO:0004857//enzyme inhibitor activity;GO:0019899//enzyme binding;GO:0070095//fructose-6-phosphate binding","GO:0000060//protein import into nucleus, translocation;GO:0009750//response to fructose;GO:0006110//regulation of glycolytic process;GO:1901135//carbohydrate derivative metabolic process;GO:0001678//cellular glucose homeostasis;GO:0070328//triglyceride homeostasis;GO:0005975//carbohydrate metabolic process;GO:0033132//negative regulation of glucokinase activity;GO:0033133//positive regulation of glucokinase activity;GO:0046415//urate metabolic process","NA","NP_001477.2//glucokinase regulatory protein [Homo sapiens]","3//A2MP1"]
[4249,8163,5.76,3.67,-0.6502887485991,{"v":3.96815041045752e-11,"d":"3.97E-11"},"*",{"v":3.80072e-12,"d":"3.80E-12"},"MGAT5","GO:0070062//extracellular exosome;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0030144//alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity","GO:0006487//protein N-linked glycosylation","K00744//alpha-1,3(6)-mannosylglycoprotein beta-1,6-N-acetyl-glucosaminyltransferase [EC:2.4.1.155]","NP_002401.1//alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A [Homo sapiens]",4]
[23118,4175,15.09,9.63,-0.647985102683224,{"v":3.20138387837838E-14,"d":"3.20E-14"},"*",{"v":2.37288E-15,"d":"2.37E-15"},"TAB2","GO:0010008//endosome membrane;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0070530//K63-linked polyubiquitin modification-dependent protein binding;GO:0046872//metal ion binding;GO:0016301//kinase activity","GO:0070423//nucleotide-binding oligomerization domain containing signaling pathway;GO:0000187//activation of MAPK activity;GO:0050852//T cell receptor signaling pathway;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0007507//heart development;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0007254//JNK cascade;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0010507//negative regulation of autophagy;GO:0045860//positive regulation of protein kinase activity;GO:0002755//MyD88-dependent toll-like receptor signaling pathway","K04404//TAK1-binding protein 2","NP_001278964.1//TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform b [Homo sapiens];NP_055908.1//TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform a [Homo sapiens]","2//1;5"]
[284371,3760,1.41,0.9,-0.647698256069119,0.0535548753037623,"*",0.0229018,"ZNF841","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","XP_016882144.1//PREDICTED: zinc finger protein 841 isoform X3 [Homo sapiens];XP_016789777.1//PREDICTED: zinc finger protein 841 isoform X2 [Pan troglodytes]","1//3"]
[6785,3085,0.72,0.46,-0.646363045385299,0.256205093879348,"*",0.1456972,"ELOVL4","GO:0005783//endoplasmic reticulum;GO:0030176//integral component of endoplasmic reticulum membrane","GO:0009922//fatty acid elongase activity;GO:0008020//G-protein coupled photoreceptor activity;GO:0102336//3-oxo-arachidoyl-CoA synthase activity;GO:0102756//very-long-chain 3-ketoacyl-CoA synthase activity;GO:0102337//3-oxo-cerotoyl-CoA synthase activity;GO:0102338//3-oxo-lignoceronyl-CoA synthase activity","GO:0019367//fatty acid elongation, saturated fatty acid;GO:0006636//unsaturated fatty acid biosynthetic process;GO:0034626//fatty acid elongation, polyunsaturated fatty acid;GO:0030148//sphingolipid biosynthetic process;GO:0035338//long-chain fatty-acyl-CoA biosynthetic process;GO:0006633//fatty acid biosynthetic process;GO:0042761//very long-chain fatty acid biosynthetic process;GO:0034625//fatty acid elongation, monounsaturated fatty acid","K10249//elongation of very long chain fatty acids protein 4 [EC:2.3.1.199]","NP_073563.1//elongation of very long chain fatty acids protein 4 [Homo sapiens]","3//A2MP1"]
[245972,2370,0.86,0.55,-0.644905041177438,0.286129816718801,"*",0.1660642,"ATP6V0D2","GO:0033179//proton-transporting V-type ATPase, V0 domain;GO:0016020//membrane;GO:0005765//lysosomal membrane;GO:0070062//extracellular exosome;GO:0010008//endosome membrane;GO:0016324//apical plasma membrane;GO:0030670//phagocytic vesicle membrane;GO:0016471//vacuolar proton-transporting V-type ATPase complex;GO:0005769//early endosome","GO:0015078//hydrogen ion transmembrane transporter activity;GO:0008553//hydrogen-exporting ATPase activity, phosphorylative mechanism;GO:0046961//proton-transporting ATPase activity, rotational mechanism","GO:0016241//regulation of macroautophagy;GO:0008286//insulin receptor signaling pathway;GO:0034220//ion transmembrane transport;GO:0090383//phagosome acidification;GO:0007034//vacuolar transport;GO:0007035//vacuolar acidification;GO:0015991//ATP hydrolysis coupled proton transport;GO:0033572//transferrin transport","K02146//V-type H+-transporting ATPase subunit d","CAH92343.1//hypothetical protein [Pongo abelii]","1//3"]
[9724,5537,3.08,1.97,-0.644734721238525,0.00014718977883959,"*",{"v":3.50974E-5,"d":"3.51E-05"},"UTP14C","GO:0032040//small-subunit processome;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0019013//viral nucleocapsid","NA","GO:0030154//cell differentiation;GO:0007275//multicellular organism development;GO:0051321//meiotic cell cycle;GO:0006364//rRNA processing;GO:0007283//spermatogenesis;GO:0030490//maturation of SSU-rRNA","K14567//U3 small nucleolar RNA-associated protein 14","NP_067677.4//U3 small nucleolar RNA-associated protein 14 homolog C [Homo sapiens]",5]
[5340,1200,0.75,0.48,-0.643856189774725,0.156398330602763,"*",0.080079,"PLG","GO:0044218//other organism cell membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0072562//blood microparticle;GO:0031232//extrinsic component of external side of plasma membrane;GO:0031093//platelet alpha granule lumen;GO:0009986//cell surface;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0004252//serine-type endopeptidase activity;GO:0004175//endopeptidase activity;GO:0034185//apolipoprotein binding;GO:0005102//receptor binding;GO:1904854//proteasome core complex binding;GO:0051087//chaperone binding;GO:0008236//serine-type peptidase activity;GO:1990405//protein antigen binding;GO:0019904//protein domain specific binding;GO:0019900//kinase binding;GO:0019899//enzyme binding","GO:0048771//tissue remodeling;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0007596//blood coagulation;GO:0042246//tissue regeneration;GO:0051918//negative regulation of fibrinolysis;GO:0044267//cellular protein metabolic process;GO:0002576//platelet degranulation;GO:0045445//myoblast differentiation;GO:0008285//negative regulation of cell proliferation;GO:0042730//fibrinolysis;GO:0071674//mononuclear cell migration;GO:0060716//labyrinthine layer blood vessel development;GO:0060707//trophoblast giant cell differentiation;GO:0052213//interaction with symbiont via secreted substance involved in symbiotic interaction;GO:0046716//muscle cell cellular homeostasis;GO:0022617//extracellular matrix disassembly;GO:0006508//proteolysis;GO:0051702//interaction with symbiont;GO:0051919//positive regulation of fibrinolysis;GO:0010812//negative regulation of cell-substrate adhesion;GO:2000048//negative regulation of cell-cell adhesion mediated by cadherin;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0052182//modification by host of symbiont morphology or physiology via secreted substance","K01315//plasminogen [EC:3.4.21.7]","AAA36451.1//plasminogen [Homo sapiens];NP_000292.1//plasminogen isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[389177,1902,22.81,14.62,-0.6417231353597,{"v":6.44561791363636e-10,"d":"6.45E-10"},"*",{"v":7.10172e-11,"d":"7.10E-11"},"TMEM212","NA","NA","NA","K22196//transmembrane protein 212","KRX57831.1//LINE-1 reverse transcriptase -like protein [Trichinella sp. T6]","1//3"]
[23245,3516,16.96,10.88,-0.64045761331286,{"v":1.79798394756703E-16,"d":"1.80E-16"},"*",{"v":1.133448E-17,"d":"1.13E-17"},"ASTN2","GO:0060187//cell pole;GO:0005770//late endosome;GO:0005938//cell cortex;GO:0030136//clathrin-coated vesicle;GO:0016021//integral component of membrane;GO:0005769//early endosome;GO:0043204//perikaryon","GO:0005509//calcium ion binding;GO:0043533//inositol 1,3,4,5 tetrakisphosphate binding","GO:2000009//negative regulation of protein localization to cell surface;GO:0048105//establishment of body hair planar orientation;GO:0015031//protein transport","K19475//WAS/WASL-interacting protein;K10408//dynein heavy chain, axonemal;K04534//guanine nucleotide-binding protein G(o) subunit alpha;K19901//disabled homolog 2-interacting protein;K05030//calcium-activated chloride channel regulator 3/4;K14480//apolipoprotein L","NP_937829.3//astrotactin-2 isoform b [Homo sapiens];XP_011748720.1//PREDICTED: astrotactin-2 isoform X2 [Macaca nemestrina];XP_008697065.1//PREDICTED: astrotactin-2 isoform X3 [Ursus maritimus];XP_008697064.1//PREDICTED: astrotactin-2 isoform X2 [Ursus maritimus];KRX57831.1//LINE-1 reverse transcriptase -like protein [Trichinella sp. T6];XP_007966444.1//PREDICTED: astrotactin-2 isoform X4 [Chlorocebus sabaeus]","4;1//3;3//A2MP1;2//1"]
[140883,5765,2.01,1.29,-0.639824435755674,0.00268058402708248,"*",0.000817902,"ZNF280B","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","EAW59515.1//suppressor of hairy wing homolog 2 (Drosophila), isoform CRA_a, partial [Homo sapiens]","3//A2MP1"]
[84248,3682,8.9,5.72,-0.637790189075371,{"v":1.0560224492388E-7,"d":"1.06E-07"},"*",{"v":1.519842E-8,"d":"1.52E-08"},"FYTTD1","GO:0005654//nucleoplasm;GO:0016607//nuclear speck","GO:0003723//RNA binding;GO:0003729//mRNA binding","GO:0006406//mRNA export from nucleus","K15696//RING finger protein 113B;K17985//activating molecule in BECN1-regulated autophagy protein 1;K20858//calcium uniporter protein, mitochondrial;K01064//wingless-type MMTV integration site family, member 9","XP_002759822.2//PREDICTED: UAP56-interacting factor isoform X1 [Callithrix jacchus];NP_001011537.2//UAP56-interacting factor isoform 2 [Homo sapiens]","6;2//1"]
[285025,7421,0.28,0.18,-0.637429920615292,0.363629213670013,"*",0.224474,"CCDC141","GO:0005815//microtubule organizing center;GO:0005737//cytoplasm","NA","NA","K12567//titin [EC:2.7.11.1]","NP_775919.3//coiled-coil domain-containing protein 141 isoform 1 [Homo sapiens];NP_001303674.1//coiled-coil domain-containing protein 141 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[10658,5800,17.51,11.26,-0.636972256353328,{"v":1.41763610574713E-23,"d":"1.42E-23"},"*",{"v":5.40466e-25,"d":"5.40E-25"},"CELF1","GO:0016020//membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0030529//intracellular ribonucleoprotein complex;GO:0005737//cytoplasm","GO:0000900//translation repressor activity, nucleic acid binding;GO:0003723//RNA binding;GO:0036002//pre-mRNA binding;GO:0003729//mRNA binding;GO:0042835//BRE binding","GO:0043484//regulation of RNA splicing;GO:0006397//mRNA processing;GO:0016246//RNA interference;GO:0006376//mRNA splice site selection;GO:0007281//germ cell development;GO:0009790//embryo development","K13207//CUG-BP- and ETR3-like factor","EDL27515.1//CUG triplet repeat, RNA binding protein 1, isoform CRA_d, partial [Mus musculus];NP_001166110.1//CUGBP Elav-like family member 1 isoform 4 [Homo sapiens];XP_017384673.1//PREDICTED: CUGBP Elav-like family member 1 isoform X3 [Cebus capucinus imitator];XP_007113017.1//PREDICTED: CUGBP Elav-like family member 1 isoform X4 [Physeter catodon];XP_007113014.1//PREDICTED: CUGBP Elav-like family member 1 isoform X1 [Physeter catodon];XP_020034686.1//CUGBP Elav-like family member 1 isoform X2 [Castor canadensis]","1//3;3//A2MP1;2//1"]
[160287,1990,0.73,0.47,-0.63523570720238,0.335819082069395,"*",0.202366,"LDHAL6A","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0004459//L-lactate dehydrogenase activity","GO:0019752//carboxylic acid metabolic process;GO:0005975//carbohydrate metabolic process","K00016//L-lactate dehydrogenase [EC:1.1.1.27]","XP_012509723.1//PREDICTED: LOW QUALITY PROTEIN: L-lactate dehydrogenase A-like 6A [Propithecus coquereli];XP_009458321.2//PREDICTED: L-lactate dehydrogenase A-like 6A [Pan troglodytes]","1//3;4"]
[3216,1686,9.28,5.98,-0.633979320929467,0.000445974880480769,"*",1.161422E-4,"HOXB6","NA","NA","NA","K09306//homeobox protein HoxA/B/C6","XP_008951104.1//PREDICTED: homeobox protein Hox-B6 isoform X1 [Pan paniscus]",4]
[201299,964,2.9,1.87,-0.633014630127298,0.252138585924207,"*",0.1428638,"RDM1","GO:0016605//PML body;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0015030//Cajal body","GO:0003723//RNA binding;GO:0003677//DNA binding","GO:0006281//DNA repair;GO:0006310//DNA recombination","K10874//RAD52 motif-containing protein 1","NP_001156592.1//RAD52 motif-containing protein 1 isoform 3 [Homo sapiens];NP_001156593.1//RAD52 motif-containing protein 1 isoform 4 [Homo sapiens];NP_001156596.1//RAD52 motif-containing protein 1 isoform 6 [Homo sapiens];NP_001317123.1//RAD52 motif-containing protein 1 isoform 9 [Homo sapiens];NP_001030008.1//RAD52 motif-containing protein 1 isoform 2 [Homo sapiens];NP_001156594.1//RAD52 motif-containing protein 1 isoform 5 [Homo sapiens];NP_663629.1//RAD52 motif-containing protein 1 isoform 1 [Homo sapiens];NP_001156597.1//RAD52 motif-containing protein 1 isoform 7 [Homo sapiens];NP_001156602.1//RAD52 motif-containing protein 1 isoform 8 [Homo sapiens]","1//3;3//A2MP1"]
[80817,4488,2.03,1.31,-0.631912915647726,0.0126683794969217,"*",4.50856E-3,"CEP44","GO:0000922//spindle pole;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0030496//midbody","NA","NA","K16761//centrosomal protein CEP44","NP_001035247.1//centrosomal protein of 44 kDa isoform a [Homo sapiens];NP_001138786.1//centrosomal protein of 44 kDa isoform b [Homo sapiens]","1//3;2//1"]
[26996,2021,1.47,0.95,-0.629816736505417,0.188229898543517,"*",0.0995118,"GPR160","GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0043235//receptor complex","GO:0004930//G-protein coupled receptor activity","NA","K08438//G protein-coupled receptor 160","NP_055188.1//probable G-protein coupled receptor 160 [Homo sapiens]","2//1"]
[90649,3897,1.16,0.75,-0.629162304631691,0.0844650009920088,"*",0.0383778,"ZNF486","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_009192262.2//LOW QUALITY PROTEIN: putative zinc finger protein 66 [Papio anubis]","3//A2MP1"]
[1840,3317,0.34,0.22,-0.628031222613042,0.458957618181818,"*",0.309726,"DTX1","GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0003713//transcription coactivator activity;GO:0008270//zinc ion binding;GO:0031625//ubiquitin protein ligase binding;GO:0005112//Notch binding;GO:0016740//transferase activity;GO:0017124//SH3 domain binding","GO:0008593//regulation of Notch signaling pathway;GO:0010001//glial cell differentiation;GO:0016567//protein ubiquitination;GO:0006351//transcription, DNA-templated;GO:0007166//cell surface receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0045665//negative regulation of neuron differentiation;GO:1990830//cellular response to leukemia inhibitory factor;GO:0045581//negative regulation of T cell differentiation;GO:0007219//Notch signaling pathway","K06058//deltex [EC:2.3.2.27]","NP_004407.2//E3 ubiquitin-protein ligase DTX1 [Homo sapiens]","2//1"]
[151011,3683,15.01,9.72,-0.626895758014908,{"v":6.94961157692308e-19,"d":"6.95E-19"},"*",{"v":3.61968e-20,"d":"3.62E-20"},"2019-09-10","GO:0005856//cytoskeleton;GO:0005737//cytoplasm","GO:0005525//GTP binding","GO:0051301//cell division;GO:0007049//cell cycle","K16940//septin 10","AAH50345.2//SEPT10 protein [Homo sapiens];NP_001039641.1//septin-10 [Bos taurus];XP_012578710.1//PREDICTED: LOW QUALITY PROTEIN: septin-10 [Condylura cristata];XP_005415300.2//PREDICTED: septin-10 isoform X1 [Chinchilla lanigera];EPQ19193.1//Septin-10 [Myotis brandtii];XP_011509003.1//PREDICTED: septin-10 isoform X6 [Homo sapiens];NP_001308435.1//septin-10 isoform 12 [Homo sapiens];XP_011509005.1//PREDICTED: septin-10 isoform X1 [Homo sapiens];XP_019682488.1//PREDICTED: septin-10 isoform X1 [Felis catus];XP_006215508.2//PREDICTED: septin-10 [Vicugna pacos];XP_011509004.1//PREDICTED: septin-10 isoform X7 [Homo sapiens];NP_001308440.1//septin-10 isoform 17 [Homo sapiens];NP_001308431.1//septin-10 isoform 8 [Homo sapiens];NP_001308432.1//septin-10 isoform 9 [Homo sapiens];NP_001308439.1//septin-10 isoform 16 [Homo sapiens]","4;1//3;3//A2MP1"]
[5570,2012,0.88,0.57,-0.626541604472556,0.318052750173156,"*",0.1897286,"PKIB","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0004862//cAMP-dependent protein kinase inhibitor activity","GO:1904355//positive regulation of telomere capping;GO:2000480//negative regulation of cAMP-dependent protein kinase activity;GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0051973//positive regulation of telomerase activity","K09228//KRAB domain-containing zinc finger protein;K15985//cAMP-dependent protein kinase inhibitor alpha","XP_008005377.1//PREDICTED: cAMP-dependent protein kinase inhibitor beta isoform X2 [Chlorocebus sabaeus];XP_016811732.1//PREDICTED: cAMP-dependent protein kinase inhibitor beta isoform X1 [Pan troglodytes];EAW48170.1//protein kinase (cAMP-dependent, catalytic) inhibitor beta, isoform CRA_c, partial [Homo sapiens]","1//3;2//1;5"]
[2180,3781,5.97,3.87,-0.625397365120395,{"v":1.94195746236559E-5,"d":"1.94E-05"},"*",{"v":3.9571e-06,"d":"3.96E-06"},"ACSL1","GO:0016021//integral component of membrane;GO:0005739//mitochondrion","GO:0004467//long-chain fatty acid-CoA ligase activity;GO:0003824//catalytic activity","GO:0033211//adiponectin-activated signaling pathway;GO:0008152//metabolic process;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0044539//long-chain fatty acid import;GO:0008610//lipid biosynthetic process","K01897//long-chain acyl-CoA synthetase [EC:6.2.1.3]","XP_007998596.1//PREDICTED: long-chain-fatty-acid--CoA ligase 1 isoform X2 [Chlorocebus sabaeus];XP_021567574.1//long-chain-fatty-acid--CoA ligase 1 isoform X2 [Carlito syrichta]","1//3;3//A2MP1"]
[23142,4284,6.32,4.1,-0.624300648671657,{"v":2.2362459e-06,"d":"2.24E-06"},"*",{"v":3.9198e-07,"d":"3.92E-07"},"DCUN1D4","GO:0005634//nucleus;GO:0000151//ubiquitin ligase complex","GO:0032182//ubiquitin-like protein binding;GO:0097602//cullin family protein binding;GO:0031624//ubiquitin conjugating enzyme binding","GO:0045116//protein neddylation;GO:0051443//positive regulation of ubiquitin-protein transferase activity","K17824//DCN1-like protein 4/5","NP_001274684.1//DCN1-like protein 4 isoform 3 [Homo sapiens];XP_011928981.1//PREDICTED: DCN1-like protein 4 isoform X4 [Cercocebus atys];XP_012416428.1//PREDICTED: LOW QUALITY PROTEIN: DCN1-like protein 4 [Odobenus rosmarus divergens]","1//3;3//A2MP1;2//1"]
[8567,5831,10.57,6.86,-0.623694895209871,{"v":4.25049238051044e-13,"d":"4.25E-13"},"*",{"v":3.44052e-14,"d":"3.44E-14"},"MADD","GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0016301//kinase activity;GO:0005123//death receptor binding;GO:0030295//protein kinase activator activity;GO:0017112//Rab guanyl-nucleotide exchange factor activity","GO:0032483//regulation of Rab protein signal transduction;GO:0000187//activation of MAPK activity;GO:0007166//cell surface receptor signaling pathway;GO:0010803//regulation of tumor necrosis factor-mediated signaling pathway;GO:0061024//membrane organization;GO:2001236//regulation of extrinsic apoptotic signaling pathway;GO:1902041//regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0097194//execution phase of apoptosis;GO:0051726//regulation of cell cycle;GO:0042981//regulation of apoptotic process","K18061//myotubularin-related protein 5/13;K20163//DENN domain-containing protein 4","NP_569830.2//MAP kinase-activating death domain protein isoform f [Homo sapiens];NP_003673.3//MAP kinase-activating death domain protein isoform d [Homo sapiens];NP_001129415.1//MAP kinase-activating death domain protein isoform i [Homo sapiens];NP_001129416.1//MAP kinase-activating death domain protein isoform j [Homo sapiens];NP_569831.1//MAP kinase-activating death domain protein isoform g [Homo sapiens];NP_569829.2//MAP kinase-activating death domain protein isoform e [Homo sapiens];NP_569826.2//MAP kinase-activating death domain protein isoform a [Homo sapiens];NP_569828.2//MAP kinase-activating death domain protein isoform c [Homo sapiens];NP_569832.2//MAP kinase-activating death domain protein isoform h [Homo sapiens];NP_569827.2//MAP kinase-activating death domain protein isoform b [Homo sapiens]","1//3;3//A2MP1;2//1"]
[8897,9008,2.91,1.89,-0.622632918687211,{"v":2.7275999280677e-06,"d":"2.73E-06"},"*",{"v":4.84254e-07,"d":"4.84E-07"},"MTMR3","GO:0016020//membrane;GO:0019898//extrinsic component of membrane;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0004725//protein tyrosine phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0004438//phosphatidylinositol-3-phosphatase activity;GO:0052629//phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity","GO:2000785//regulation of autophagosome assembly;GO:0006470//protein dephosphorylation;GO:0006661//phosphatidylinositol biosynthetic process;GO:0046856//phosphatidylinositol dephosphorylation;GO:1904562//phosphatidylinositol 5-phosphate metabolic process;GO:0042149//cellular response to glucose starvation;GO:0016236//macroautophagy","K18082//myotubularin-related protein 3/4 [EC:3.1.3.48 3.1.3.64 3.1.3.95]","XP_016884520.1//PREDICTED: myotubularin-related protein 3 isoform X7 [Homo sapiens];XP_016884519.1//PREDICTED: myotubularin-related protein 3 isoform X4 [Homo sapiens];XP_016884518.1//PREDICTED: myotubularin-related protein 3 isoform X2 [Homo sapiens]","3//A2MP1;2//1"]
[9877,4914,18.09,11.76,-0.621304347784877,{"v":1.86169745577889e-19,"d":"1.86E-19"},"*",{"v":9.27702e-21,"d":"9.28E-21"},"ZC3H11A","GO:0005654//nucleoplasm","GO:0003723//RNA binding;GO:0046872//metal ion binding","GO:0016973//poly(A)+ mRNA export from nucleus;GO:0006406//mRNA export from nucleus;GO:0006369//termination of RNA polymerase II transcription;GO:0031124//mRNA 3'-end processing;GO:0006405//RNA export from nucleus","K03243//translation initiation factor 5B","NP_001337194.1//zinc finger CCCH domain-containing protein 11A isoform 2 [Homo sapiens];NP_055642.3//zinc finger CCCH domain-containing protein 11A isoform 1 [Homo sapiens]","1//3;5"]
[2803,7881,6.18,4.02,-0.620411336725446,{"v":1.41850304721879E-10,"d":"1.42E-10"},"*",{"v":1.436796E-11,"d":"1.44E-11"},"GOLGA4","GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005802//trans-Golgi network;GO:0005737//cytoplasm;GO:0000139//Golgi membrane","GO:0051020//GTPase binding","GO:0045773//positive regulation of axon extension;GO:0043001//Golgi to plasma membrane protein transport;GO:0016192//vesicle-mediated transport","K20283//golgin subfamily A member 4","NP_002069.2//golgin subfamily A member 4 isoform 2 [Homo sapiens];NP_001166184.1//golgin subfamily A member 4 isoform 1 [Homo sapiens]","1//3;4"]
[10724,5187,13.69,8.91,-0.619625109735977,{"v":4.49159695238095e-16,"d":"4.49E-16"},"*",{"v":2.89336e-17,"d":"2.89E-17"},"MGEA5","GO:0016020//membrane;GO:0005829//cytosol","GO:0016231//beta-N-acetylglucosaminidase activity","GO:0006044//N-acetylglucosamine metabolic process;GO:0006517//protein deglycosylation","K15719//protein O-GlcNAcase / histone acetyltransferase [EC:3.2.1.169 2.3.1.48]","XP_007962118.1//PREDICTED: bifunctional protein NCOAT isoform X1 [Chlorocebus sabaeus];XP_011906972.1//PREDICTED: protein O-GlcNAcase isoform X1 [Cercocebus atys]","1//3;3//A2MP1"]
[5756,3062,34.49,22.45,-0.619462683832344,{"v":1.16504169681159e-21,"d":"1.17E-21"},"*",{"v":5.03242e-23,"d":"5.03E-23"},"TWF1","GO:0005925//focal adhesion;GO:0032587//ruffle membrane;GO:0030016//myofibril;GO:0048471//perinuclear region of cytoplasm;GO:0030175//filopodium;GO:0005911//cell-cell junction;GO:0005829//cytosol;GO:0015629//actin cytoskeleton","GO:0004713//protein tyrosine kinase activity;GO:0005524//ATP binding;GO:0003785//actin monomer binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0032403//protein complex binding;GO:0045296//cadherin binding","GO:0042989//sequestering of actin monomers;GO:0043538//regulation of actin phosphorylation;GO:0051016//barbed-end actin filament capping;GO:0010613//positive regulation of cardiac muscle hypertrophy","K08870//twinfilin","AAH43148.2//Twinfilin, actin-binding protein, homolog 1 (Drosophila) [Homo sapiens];XP_003825794.1//PREDICTED: twinfilin-1 isoform X2 [Pan paniscus]","4;1//3"]
[134266,4105,5.48,3.57,-0.618251818931427,{"v":2.43783153387534E-5,"d":"2.44E-05"},"*",{"v":5.06826E-6,"d":"5.07E-06"},"GRPEL2","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion;GO:0001405//presequence translocase-associated import motor","GO:0051082//unfolded protein binding;GO:0051087//chaperone binding;GO:0000774//adenyl-nucleotide exchange factor activity;GO:0042803//protein homodimerization activity","GO:0006457//protein folding;GO:0030150//protein import into mitochondrial matrix","K03687//molecular chaperone GrpE","CAD38619.1//hypothetical protein, partial [Homo sapiens]","3//A2MP1"]
[84247,5355,10.91,7.11,-0.617729636704192,{"v":2.38398899346405e-12,"d":"2.38E-12"},"*",{"v":2.05506e-13,"d":"2.06E-13"},"RTL6","NA","NA","NA","K12012//tripartite motif-containing protein 35","NP_115663.2//retrotransposon Gag-like protein 6 [Homo sapiens]","2//1"]
[26512,5535,3.16,2.06,-0.617280220993884,{"v":1.8465252698609E-5,"d":"1.85E-05"},"*",{"v":3.73952e-06,"d":"3.74E-06"},"INTS6","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0015629//actin cytoskeleton;GO:0032039//integrator complex","GO:0004888//transmembrane signaling receptor activity","GO:0042795//snRNA transcription from RNA polymerase II promoter;GO:0016180//snRNA processing","K13143//integrator complex subunit 6","NP_036273.1//integrator complex subunit 6 isoform a [Homo sapiens];AAQ96237.1//LRRGT00024 [Rattus norvegicus]","1//3;2//1"]
[54843,3416,3.22,2.1,-0.616671360448494,0.0174632458111544,"*",0.00644896,"SYTL2","GO:0016020//membrane;GO:0070382//exocytic vesicle;GO:0005622//intracellular;GO:0042470//melanosome;GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0019897//extrinsic component of plasma membrane","GO:0005544//calcium-dependent phospholipid binding;GO:0042043//neurexin family protein binding;GO:0030276//clathrin binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0005509//calcium ion binding;GO:0019902//phosphatase binding;GO:0019905//syntaxin binding;GO:0001786//phosphatidylserine binding;GO:0017137//Rab GTPase binding","GO:0072659//protein localization to plasma membrane;GO:0070257//positive regulation of mucus secretion;GO:0006904//vesicle docking involved in exocytosis;GO:0016192//vesicle-mediated transport;GO:0006886//intracellular protein transport;GO:0006906//vesicle fusion;GO:0010923//negative regulation of phosphatase activity;GO:0006887//exocytosis","K17598//synaptotagmin-like protein","NP_116561.1//synaptotagmin-like protein 2 isoform a [Homo sapiens];XP_012360328.1//PREDICTED: synaptotagmin-like protein 2 isoform X10 [Nomascus leucogenys];NP_996813.1//synaptotagmin-like protein 2 isoform f [Homo sapiens];XP_016873427.1//PREDICTED: synaptotagmin-like protein 2 isoform X19 [Homo sapiens];XP_005274118.1//PREDICTED: synaptotagmin-like protein 2 isoform X14 [Homo sapiens];XP_016873428.1//PREDICTED: synaptotagmin-like protein 2 isoform X20 [Homo sapiens];NP_001156425.1//synaptotagmin-like protein 2 isoform i [Homo sapiens];NP_001156423.1//synaptotagmin-like protein 2 isoform g [Homo sapiens]","4;1//3;3//A2MP1;2//1"]
[134553,4424,12.35,8.06,-0.615659297944073,{"v":4.28579757666667E-14,"d":"4.29E-14"},"*",{"v":3.21958e-15,"d":"3.22E-15"},"C5orf24","NA","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K02927//large subunit ribosomal protein L40e;K15696//RING finger protein 113B;K17985//activating molecule in BECN1-regulated autophagy protein 1;K01064//wingless-type MMTV integration site family, member 9","XP_012360486.1//PREDICTED: UPF0461 protein C5orf24 homolog isoform X3 [Nomascus leucogenys];XP_012360484.1//PREDICTED: UPF0461 protein C5orf24 homolog isoform X1 [Nomascus leucogenys];EDL41223.1//RIKEN cDNA B230219D22, partial [Mus musculus]","1//3;3//A2MP1"]
[26054,6483,5.45,3.56,-0.614378988697891,{"v":5.16403962179199e-08,"d":"5.16E-08"},"*",{"v":7.18e-09,"d":"7.18E-09"},"SENP6","GO:0005654//nucleoplasm;GO:0005829//cytosol","GO:0008234//cysteine-type peptidase activity;GO:0016929//SUMO-specific protease activity","GO:0016925//protein sumoylation;GO:0070646//protein modification by small protein removal;GO:0090169//regulation of spindle assembly;GO:0090234//regulation of kinetochore assembly;GO:0016926//protein desumoylation","K08595//sentrin-specific protease 6 [EC:3.4.22.68]","NP_001291721.1//sentrin-specific protease 6 isoform 3 [Homo sapiens];NP_001093879.1//sentrin-specific protease 6 isoform 2 [Homo sapiens];NP_056386.2//sentrin-specific protease 6 isoform 1 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[5933,5916,7.11,4.65,-0.612618843624022,{"v":4.85999289963973e-09,"d":"4.86E-09"},"*",{"v":5.91146e-10,"d":"5.91E-10"},"RBL1","GO:0005654//nucleoplasm;GO:0005667//transcription factor complex","GO:1990841//promoter-specific chromatin binding;GO:0008134//transcription factor binding","GO:0006351//transcription, DNA-templated;GO:0010629//negative regulation of gene expression;GO:0016032//viral process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0016569//covalent chromatin modification;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0051726//regulation of cell cycle;GO:0007049//cell cycle;GO:0043550//regulation of lipid kinase activity","K04681//retinoblastoma-like protein 1","XP_006723905.1//PREDICTED: retinoblastoma-like protein 1 isoform X3 [Homo sapiens];XP_021776761.1//retinoblastoma-like protein 1 isoform X4 [Papio anubis];NP_002886.2//retinoblastoma-like protein 1 isoform a [Homo sapiens]","4;1//3;3//A2MP1"]
[254887,5323,1.85,1.21,-0.612518223241718,0.000232996146490336,"*",{"v":5.7352e-05,"d":"5.74E-05"},"ZDHHC23","GO:0016021//integral component of membrane","GO:0019706//protein-cysteine S-palmitoyltransferase activity","GO:0018345//protein palmitoylation;GO:0072659//protein localization to plasma membrane","K18932//palmitoyltransferase [EC:2.3.1.225]","NP_775841.2//palmitoyltransferase ZDHHC23 isoform c [Homo sapiens];NP_001307397.1//palmitoyltransferase ZDHHC23 isoform b [Homo sapiens];NP_001307396.1//palmitoyltransferase ZDHHC23 isoform a [Homo sapiens]","4;1//3"]
[4552,3291,15.49,10.14,-0.611279491786228,{"v":1.24142532445551E-10,"d":"1.24E-10"},"*",{"v":1.248886E-11,"d":"1.25E-11"},"MTRR","GO:0005829//cytosol","GO:0003958//NADPH-hemoprotein reductase activity;GO:0050660//flavin adenine dinucleotide binding;GO:0070402//NADPH binding;GO:0050444//aquacobalamin reductase (NADPH) activity;GO:0050661//NADP binding;GO:0010181//FMN binding;GO:0016723//oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor;GO:0030586//[methionine synthase] reductase activity;GO:0071949//FAD binding","GO:0043418//homocysteine catabolic process;GO:0055114//oxidation-reduction process;GO:0006306//DNA methylation;GO:0033353//S-adenosylmethionine cycle;GO:0006555//methionine metabolic process;GO:1904042//negative regulation of cystathionine beta-synthase activity;GO:0000096//sulfur amino acid metabolic process;GO:0032259//methylation;GO:0009235//cobalamin metabolic process;GO:0046655//folic acid metabolic process;GO:0009086//methionine biosynthetic process","K00597//methionine synthase reductase [EC:1.16.1.8]","NP_076915.2//methionine synthase reductase isoform 2 [Homo sapiens]","2//1"]
[84056,7521,3.13,2.05,-0.610538747427172,{"v":1.89418658243451e-05,"d":"1.89E-05"},"*",{"v":3.8479E-6,"d":"3.85E-06"},"KATNAL1","GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005874//microtubule;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0030496//midbody","GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0008568//microtubule-severing ATPase activity;GO:0008017//microtubule binding","GO:0051301//cell division;GO:0051013//microtubule severing;GO:0007049//cell cycle","K07767//katanin p60 ATPase-containing subunit A1 [EC:3.6.4.3]","NP_115492.1//katanin p60 ATPase-containing subunit A-like 1 [Homo sapiens]","4;2//1"]
[50507,4062,0.29,0.19,-0.610053481683986,0.458872484140234,"*",0.309726,"NOX4","GO:0005634//nucleus;GO:0005925//focal adhesion;GO:0016324//apical plasma membrane;GO:0071944//cell periphery;GO:0048471//perinuclear region of cytoplasm;GO:0001725//stress fiber;GO:0005730//nucleolus;GO:0043020//NADPH oxidase complex;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005739//mitochondrion;GO:0005886//plasma membrane","GO:0016174//NAD(P)H oxidase activity;GO:0009055//electron transfer activity;GO:0020037//heme binding;GO:0000166//nucleotide binding;GO:0072341//modified amino acid binding;GO:0019826//oxygen sensor activity;GO:0050660//flavin adenine dinucleotide binding;GO:0016175//superoxide-generating NADPH oxidase activity;GO:0016491//oxidoreductase activity","GO:0006801//superoxide metabolic process;GO:0051897//positive regulation of protein kinase B signaling;GO:0055114//oxidation-reduction process;GO:0071320//cellular response to cAMP;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0043065//positive regulation of apoptotic process;GO:0042554//superoxide anion generation;GO:0014911//positive regulation of smooth muscle cell migration;GO:0008285//negative regulation of cell proliferation;GO:0045453//bone resorption;GO:0000902//cell morphogenesis;GO:0055007//cardiac muscle cell differentiation;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0043406//positive regulation of MAP kinase activity;GO:0007569//cell aging;GO:0072593//reactive oxygen species metabolic process;GO:0071480//cellular response to gamma radiation;GO:0001666//response to hypoxia;GO:0006954//inflammatory response;GO:0071333//cellular response to glucose stimulus;GO:0051496//positive regulation of stress fiber assembly;GO:0010467//gene expression;GO:0034599//cellular response to oxidative stress;GO:0050667//homocysteine metabolic process;GO:2000573//positive regulation of DNA biosynthetic process;GO:0070374//positive regulation of ERK1 and ERK2 cascade","K21423//NADPH oxidase 4 [EC:1.6.3.-]","XP_006718912.1//PREDICTED: NADPH oxidase 4 isoform X2 [Homo sapiens];NP_001278858.1//NADPH oxidase 4 isoform f [Homo sapiens];NP_001137309.1//NADPH oxidase 4 isoform c [Homo sapiens];NP_001137308.1//NADPH oxidase 4 isoform b [Homo sapiens];NP_001278856.1//NADPH oxidase 4 isoform e [Homo sapiens];NP_058627.1//NADPH oxidase 4 isoform a [Homo sapiens]","4;1//3;2//1"]
[8690,3565,1.8,1.18,-0.609210046967833,0.0310863721212121,"*",0.01233024,"JRKL","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein;K09229//KRAB and SCAN domains-containing zinc finger protein;K19326//nesprin-1;K05164//interleukin 17 receptor A","XP_017360779.1//PREDICTED: jerky protein homolog-like [Cebus capucinus imitator]","1//3;3//A2MP1"]
[122809,6922,3.64,2.39,-0.606927832217948,{"v":6.37317445693382e-06,"d":"6.37E-06"},"*",{"v":1.199708e-06,"d":"1.20E-06"},"SOCS4","GO:0005622//intracellular;GO:0005737//cytoplasm","GO:0004860//protein kinase inhibitor activity","GO:0040008//regulation of growth;GO:0016567//protein ubiquitination;GO:0046426//negative regulation of JAK-STAT cascade;GO:0035556//intracellular signal transduction;GO:0019221//cytokine-mediated signaling pathway;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0007175//negative regulation of epidermal growth factor-activated receptor activity","K04697//suppressor of cytokine signaling 4","NP_543143.1//suppressor of cytokine signaling 4 [Homo sapiens]","1//3;2//1"]
[9633,3491,2.65,1.74,-0.606905053601833,0.0108793971372197,"*",0.00379696,"TESMIN","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0046872//metal ion binding","GO:0006875//cellular metal ion homeostasis;GO:0030154//cell differentiation;GO:0007275//multicellular organism development;GO:0007283//spermatogenesis;GO:0010038//response to metal ion","K16628//collagen, type VII, alpha;K21776//protein lin-54","EAW74718.1//metallothionein-like 5, testis-specific (tesmin), isoform CRA_a [Homo sapiens]","1//3;3//A2MP1"]
[23215,10394,23.61,15.52,-0.605269484041515,{"v":5.70853519833333e-48,"d":"5.71E-48"},"*",{"v":8.57674e-50,"d":"8.58E-50"},"PRRC2C","GO:0016020//membrane","GO:0003723//RNA binding;GO:0008022//protein C-terminus binding","GO:0002244//hematopoietic progenitor cell differentiation","K22016//mucin-3/17","NP_055987.2//protein PRRC2C [Homo sapiens]","3//A2MP1"]
[1737,4352,14.85,9.77,-0.604032463719743,{"v":4.48634851313756e-13,"d":"4.49E-13"},"*",{"v":3.63424e-14,"d":"3.63E-14"},"DLAT","GO:0005759//mitochondrial matrix;GO:0045254//pyruvate dehydrogenase complex;GO:0043209//myelin sheath;GO:0005739//mitochondrion;GO:0005967//mitochondrial pyruvate dehydrogenase complex","GO:0004742//dihydrolipoyllysine-residue acetyltransferase activity;GO:0034604//pyruvate dehydrogenase (NAD+) activity;GO:0042802//identical protein binding","GO:0006099//tricarboxylic acid cycle;GO:0006006//glucose metabolic process;GO:0006090//pyruvate metabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0030431//sleep;GO:0010510//regulation of acetyl-CoA biosynthetic process from pyruvate;GO:0006086//acetyl-CoA biosynthetic process from pyruvate","K00627//pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase) [EC:2.3.1.12]","NP_001922.2//dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial precursor [Homo sapiens]",4]
[3667,8743,13.69,9.01,-0.603523435444361,{"v":1.15924923294893E-23,"d":"1.16E-23"},"*",{"v":4.40506e-25,"d":"4.41E-25"},"IRS1","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005901//caveola;GO:0005899//insulin receptor complex;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0043548//phosphatidylinositol 3-kinase binding;GO:0005068//transmembrane receptor protein tyrosine kinase adaptor activity;GO:0042169//SH2 domain binding;GO:0046934//phosphatidylinositol-4,5-bisphosphate 3-kinase activity;GO:0005080//protein kinase C binding;GO:0016303//1-phosphatidylinositol-3-kinase activity;GO:0001784//phosphotyrosine residue binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0004871//signal transducer activity;GO:0005159//insulin-like growth factor receptor binding;GO:0005158//insulin receptor binding","GO:2001275//positive regulation of glucose import in response to insulin stimulus;GO:0008286//insulin receptor signaling pathway;GO:0046628//positive regulation of insulin receptor signaling pathway;GO:0048009//insulin-like growth factor receptor signaling pathway;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0042593//glucose homeostasis;GO:0046326//positive regulation of glucose import;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0019216//regulation of lipid metabolic process;GO:0010907//positive regulation of glucose metabolic process;GO:0000165//MAPK cascade;GO:0032000//positive regulation of fatty acid beta-oxidation;GO:0007165//signal transduction;GO:0032868//response to insulin;GO:0014066//regulation of phosphatidylinositol 3-kinase signaling;GO:0043434//response to peptide hormone;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0038111//interleukin-7-mediated signaling pathway;GO:0032869//cellular response to insulin stimulus;GO:0046676//negative regulation of insulin secretion;GO:0045725//positive regulation of glycogen biosynthetic process;GO:0048015//phosphatidylinositol-mediated signaling;GO:0008284//positive regulation of cell proliferation","K16172//insulin receptor substrate 1","NP_005535.1//insulin receptor substrate 1 [Homo sapiens]","2//1"]
[57460,6201,5.51,3.63,-0.602082770575407,{"v":2.33501944228382E-7,"d":"2.34E-07"},"*",{"v":3.53308e-08,"d":"3.53E-08"},"PPM1H","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm","GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity","NA","K17503//protein phosphatase 1H [EC:3.1.3.16]","XP_003906758.1//LOW QUALITY PROTEIN: protein phosphatase 1H [Papio anubis]","1//3"]
[79677,5188,10.85,7.16,-0.599663550067585,{"v":1.87798912264151e-11,"d":"1.88E-11"},"*",{"v":1.74467e-12,"d":"1.74E-12"},"SMC6","GO:0030915//Smc5-Smc6 complex;GO:0016605//PML body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000781//chromosome, telomeric region;GO:0016607//nuclear speck;GO:0005622//intracellular;GO:0000803//sex chromosome;GO:0035861//site of double-strand break;GO:0035061//interchromatin granule","GO:0005524//ATP binding;GO:0031625//ubiquitin protein ligase binding","GO:0000722//telomere maintenance via recombination;GO:0090398//cellular senescence;GO:0051984//positive regulation of chromosome segregation;GO:0000724//double-strand break repair via homologous recombination;GO:0006974//cellular response to DNA damage stimulus","K20283//golgin subfamily A member 4;K20478//golgin subfamily B member 1","NP_078900.1//structural maintenance of chromosomes protein 6 [Homo sapiens]","1//3;5"]
[6787,5871,6.44,4.25,-0.599597847089553,{"v":2.75202138959212E-8,"d":"2.75E-08"},"*",{"v":3.67476e-09,"d":"3.67E-09"},"NEK4","GO:0036064//ciliary basal body;GO:0035869//ciliary transition zone;GO:0035253//ciliary rootlet;GO:0005737//cytoplasm;GO:0097014//ciliary plasm","GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0030145//manganese ion binding","GO:0023014//signal transduction by protein phosphorylation;GO:0000278//mitotic cell cycle;GO:0007346//regulation of mitotic cell cycle;GO:0006468//protein phosphorylation;GO:0032147//activation of protein kinase activity;GO:2001020//regulation of response to DNA damage stimulus;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051301//cell division;GO:2000772//regulation of cellular senescence;GO:0031098//stress-activated protein kinase signaling cascade;GO:0006974//cellular response to DNA damage stimulus;GO:0042981//regulation of apoptotic process;GO:1900062//regulation of replicative cell aging","K08857//NIMA (never in mitosis gene a)-related kinase 1/4/5 [EC:2.7.11.1]","NP_001180462.1//serine/threonine-protein kinase Nek4 isoform 2 [Homo sapiens];NP_003148.2//serine/threonine-protein kinase Nek4 isoform 1 [Homo sapiens];XP_007982729.1//PREDICTED: serine/threonine-protein kinase Nek4 isoform X2 [Chlorocebus sabaeus]","1//3;2//1;5"]
[343035,4288,0.53,0.35,-0.598637437618233,0.256176892988442,"*",0.1456972,"RD3","NA","NA","GO:0060041//retina development in camera-type eye;GO:0050896//response to stimulus;GO:0007601//visual perception","K05727//dedicator of cytokinesis protein 3;K06238//collagen, type VI, alpha","XP_016856640.1//PREDICTED: protein RD3 isoform X1 [Homo sapiens]","1//3;2//1"]
[255308,2096,0.56,0.37,-0.597901556428654,0.459085378491231,"*",0.309726,"EIF2S3B","NA","NA","NA","K03242//translation initiation factor 2 subunit 3","AAH87847.1//Unknown (protein for IMAGE:30389268), partial [Homo sapiens];Q2VIR3.2//PUTATIVE PSEUDOGENE: RecName: Full=Putative eukaryotic translation initiation factor 2 subunit 3-like protein; AltName: Full=Eukaryotic translation initiation factor 2 subunit gamma A; Short=eIF-2-gamma A; Short=eIF-2gA","1//3"]
[8317,3201,5.02,3.32,-0.596504122603847,0.000718772555463347,"*",0.0001951944,"CDC7","GO:0072686//mitotic spindle;GO:0045171//intercellular bridge;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0016301//kinase activity","GO:0000727//double-strand break repair via break-induced replication;GO:0006260//DNA replication;GO:0006270//DNA replication initiation;GO:0008360//regulation of cell shape;GO:0010571//positive regulation of nuclear cell cycle DNA replication;GO:0044770//cell cycle phase transition;GO:0018105//peptidyl-serine phosphorylation;GO:0051301//cell division;GO:0010971//positive regulation of G2/M transition of mitotic cell cycle;GO:0000082//G1/S transition of mitotic cell cycle;GO:0006909//phagocytosis;GO:0008284//positive regulation of cell proliferation","K02214//cell division control protein 7 [EC:2.7.11.1]","XP_018884451.1//PREDICTED: cell division cycle 7-related protein kinase isoform X1 [Gorilla gorilla gorilla]","1//3;3//A2MP1"]
[348801,2233,1.51,1,-0.594548549550354,0.185113975151443,"*",0.0975632,"LNP1","NA","NA","NA","NA","XP_018879099.1//PREDICTED: leukemia NUP98 fusion partner 1 isoform X2 [Gorilla gorilla gorilla]","1//3"]
[5069,10995,8.74,5.79,-0.594069931511362,{"v":1.28311482719812e-18,"d":"1.28E-18"},"*",{"v":6.85174e-20,"d":"6.85E-20"},"PAPPA","GO:0005615//extracellular space;GO:0016021//integral component of membrane;GO:0005576//extracellular region","GO:0008237//metallopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding","GO:0044267//cellular protein metabolic process;GO:0007565//female pregnancy;GO:0051384//response to glucocorticoid;GO:0032354//response to follicle-stimulating hormone","K07762//pappalysin-1 [EC:3.4.24.79]","NP_002572.2//pappalysin-1 preproprotein [Homo sapiens]",4]
[120526,3000,6.17,4.09,-0.593169646207669,2.99345053071375E-4,"*",{"v":7.53516e-05,"d":"7.54E-05"},"DNAJC24","GO:0005856//cytoskeleton;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0001671//ATPase activator activity;GO:0008270//zinc ion binding;GO:0008198//ferrous iron binding","GO:0017183//peptidyl-diphthamide biosynthetic process from peptidyl-histidine;GO:0032781//positive regulation of ATPase activity;GO:0055114//oxidation-reduction process;GO:0061077//chaperone-mediated protein folding","K17867//diphthamide biosynthesis protein 4","NP_859057.4//dnaJ homolog subfamily C member 24 [Homo sapiens]",4]
[1290,6930,14.65,9.72,-0.591872445703829,{"v":1.87611322961104E-19,"d":"1.88E-19"},"*",{"v":9.3606e-21,"d":"9.36E-21"},"COL5A2","GO:0031012//extracellular matrix;GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0005588//collagen type V trimer;GO:0005576//extracellular region","GO:0046872//metal ion binding;GO:0005201//extracellular matrix structural constituent;GO:0046332//SMAD binding","GO:0043588//skin development;GO:0030199//collagen fibril organization;GO:0001503//ossification;GO:0048592//eye morphogenesis;GO:1903225//negative regulation of endodermal cell differentiation;GO:0071230//cellular response to amino acid stimulus;GO:0030198//extracellular matrix organization;GO:0001501//skeletal system development;GO:0030574//collagen catabolic process","K19721//collagen, type V/XI/XXIV/XXVII, alpha","BAD92282.1//alpha 2 type V collagen preproprotein variant, partial [Homo sapiens]",4]
[84912,6816,12.32,8.18,-0.590829507753152,{"v":3.87286660273973e-16,"d":"3.87E-16"},"*",{"v":2.47782E-17,"d":"2.48E-17"},"SLC35B4","GO:0005783//endoplasmic reticulum;GO:0030173//integral component of Golgi membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0005462//UDP-N-acetylglucosamine transmembrane transporter activity;GO:0005457//GDP-fucose transmembrane transporter activity;GO:0005464//UDP-xylose transmembrane transporter activity","GO:0015790//UDP-xylose transmembrane transport;GO:0015783//GDP-fucose transmembrane transport;GO:0008643//carbohydrate transport;GO:1990569//UDP-N-acetylglucosamine transmembrane transport;GO:0006111//regulation of gluconeogenesis","K15278//solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4","NP_116215.1//UDP-xylose and UDP-N-acetylglucosamine transporter [Homo sapiens]",4]
[10827,4553,3.13,2.08,-0.589579128791526,0.00173686032123024,"*",0.000509076,"FAM114A2","NA","GO:0017076//purine nucleotide binding","NA","NA","NP_061161.2//protein FAM114A2 isoform 1 [Homo sapiens];XP_011740774.1//PREDICTED: protein FAM114A2 isoform X1 [Macaca nemestrina];NP_001304924.1//protein FAM114A2 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[219654,4933,1.88,1.25,-0.58880456701555,0.0150062756824079,"*",0.00543078,"ZCCHC24","NA","GO:0003723//RNA binding;GO:0008270//zinc ion binding;GO:0003676//nucleic acid binding","NA","K10955//mucin-2","XP_017720713.1//PREDICTED: zinc finger CCHC domain-containing protein 24 [Rhinopithecus bieti]","3//A2MP1"]
[55175,7410,2.81,1.87,-0.587531860333289,1.17927143731544E-4,"*",{"v":2.74996E-5,"d":"2.75E-05"},"KLHL11","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0019005//SCF ubiquitin ligase complex","GO:0031625//ubiquitin protein ligase binding","GO:0043687//post-translational protein modification;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0030162//regulation of proteolysis;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process","K10449//kelch-like protein 11","XP_004434534.2//PREDICTED: kelch-like protein 11 [Ceratotherium simum simum]","2//1"]
[27125,9580,5.48,3.65,-0.586279429193147,{"v":2.33389254294294e-10,"d":"2.33E-10"},"*",{"v":2.43266E-11,"d":"2.43E-11"},"AFF4","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0008023//transcription elongation factor complex;GO:0035327//transcriptionally active chromatin;GO:0001650//fibrillar center","GO:0003700//DNA binding transcription factor activity","GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0007286//spermatid development;GO:0006366//transcription from RNA polymerase II promoter","K15185//AF4/FMR2 family member 4","NP_055238.1//AF4/FMR2 family member 4 [Homo sapiens]","3//A2MP1"]
[340578,2612,0.09,0.06,-0.584962500721156,0.782986118466899,"*",0.689316,"DCAF12L2","NA","NA","NA","K11803//WD repeat-containing protein 40A","XP_012331827.1//DDB1- and CUL4-associated factor 12-like protein 2 [Aotus nancymaae]","2//1"]
[1124,3150,0.09,0.06,-0.584962500721156,0.782318563694494,"*",0.689316,"CHN2","GO:0016020//membrane;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005737//cytoplasm","GO:0005070//SH3/SH2 adaptor activity;GO:0046872//metal ion binding;GO:0005096//GTPase activator activity","GO:0043087//regulation of GTPase activity;GO:0035556//intracellular signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction","K20630//chimaerin","NP_001280010.1//beta-chimaerin isoform 14 [Homo sapiens];NP_001280004.1//beta-chimaerin isoform 8 [Homo sapiens];NP_001280000.1//beta-chimaerin isoform 5 [Homo sapiens];NP_001279998.1//beta-chimaerin isoform 3 [Homo sapiens];NP_001280002.1//beta-chimaerin isoform 7 [Homo sapiens];EHH17412.1//hypothetical protein EGK_13814 [Macaca mulatta];XP_011937965.1//PREDICTED: LOW QUALITY PROTEIN: beta-chimaerin-like [Cercocebus atys];NP_004058.1//beta-chimaerin isoform 2 [Homo sapiens];XP_014335491.1//PREDICTED: beta-chimaerin isoform X6 [Bos mutus];NP_001279999.1//beta-chimaerin isoform 4 [Homo sapiens];XP_005901472.2//PREDICTED: beta-chimaerin isoform X3 [Bos mutus];XP_011729588.1//PREDICTED: beta-chimaerin isoform X9 [Macaca nemestrina]","1//3;3//A2MP1;2//1"]
[154214,11324,1.44,0.96,-0.584962500721156,0.000778453841226264,"*",2.1301E-4,"RNF217","GO:0000151//ubiquitin ligase complex;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005737//cytoplasm","GO:0061630//ubiquitin protein ligase activity;GO:0046872//metal ion binding;GO:0004842//ubiquitin-protein transferase activity;GO:0031624//ubiquitin conjugating enzyme binding","GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0000209//protein polyubiquitination","K11977//E3 ubiquitin-protein ligase RNF217 [EC:2.3.2.27]","NP_689766.1//probable E3 ubiquitin-protein ligase RNF217 isoform b [Homo sapiens];NP_001273327.1//probable E3 ubiquitin-protein ligase RNF217 isoform a [Homo sapiens]","4;2//1"]
[85442,3278,1.11,0.74,-0.584962500721156,0.103315283817649,"*",0.0485208,"KNDC1","GO:0030425//dendrite;GO:0043204//perikaryon;GO:0043025//neuronal cell body;GO:0032045//guanyl-nucleotide exchange factor complex","GO:0005088//Ras guanyl-nucleotide exchange factor activity","GO:0050773//regulation of dendrite development;GO:0007264//small GTPase mediated signal transduction;GO:0001934//positive regulation of protein phosphorylation;GO:0048814//regulation of dendrite morphogenesis;GO:0021707//cerebellar granule cell differentiation","K06689//ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23];K12581//CCR4-NOT transcription complex subunit 7/8;K16628//collagen, type VII, alpha;K04957//hyperpolarization activated cyclic nucleotide-gated potassium channel 4;K11447//histone demethylase [EC:1.14.11.-];K14317//nuclear pore complex protein Nup214;K01064//wingless-type MMTV integration site family, member 9","NP_689856.6//protein very KIND isoform 1 [Homo sapiens];NP_001334793.1//protein very KIND isoform 2 [Homo sapiens];NP_001334795.1//protein very KIND isoform 4 [Homo sapiens];NP_001334794.1//protein very KIND isoform 3 [Homo sapiens]","1//3;7"]
[23220,5478,2.67,1.78,-0.584962500721156,0.00280872361780318,"*",8.6122E-4,"DTX4","GO:0005829//cytosol","GO:0008270//zinc ion binding;GO:0004842//ubiquitin-protein transferase activity","GO:0032479//regulation of type I interferon production;GO:0007219//Notch signaling pathway","K06058//deltex [EC:2.3.2.27]","XP_003275396.1//PREDICTED: E3 ubiquitin-protein ligase DTX4 [Nomascus leucogenys];NP_055992.1//E3 ubiquitin-protein ligase DTX4 isoform 1 [Homo sapiens]","1//3"]
[51168,11876,0.03,0.02,-0.584962500721156,0.813017131242579,"*",0.728682,"MYO15A","GO:0070062//extracellular exosome;GO:0016459//myosin complex;GO:0032420//stereocilium;GO:0005737//cytoplasm","GO:0003779//actin binding;GO:0005524//ATP binding;GO:0003774//motor activity;GO:0005516//calmodulin binding","GO:0007626//locomotory behavior;GO:0042472//inner ear morphogenesis;GO:0007605//sensory perception of sound","K10361//myosin XV","NP_057323.3//unconventional myosin-XV [Homo sapiens]","3//A2MP1"]
[8820,1182,0.21,0.14,-0.584962500721156,0.781707637654409,"*",0.689316,"HESX1","GO:0005634//nucleus","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:0008022//protein C-terminus binding;GO:0047485//protein N-terminus binding;GO:0003682//chromatin binding;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0006355//regulation of transcription, DNA-templated;GO:0021983//pituitary gland development;GO:0006351//transcription, DNA-templated;GO:0048853//forebrain morphogenesis;GO:0007420//brain development;GO:0030916//otic vesicle formation;GO:0043584//nose development","K09354//homeobox protein expressed in ES cells 1","XP_003257267.1//PREDICTED: homeobox expressed in ES cells 1 [Nomascus leucogenys]","2//1"]
[2301,2000,0.12,0.08,-0.584962500721156,0.781153077752554,"*",0.689316,"FOXE3","GO:0005634//nucleus;GO:0005667//transcription factor complex","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0003677//DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0009653//anatomical structure morphogenesis;GO:0001654//eye development;GO:0030154//cell differentiation;GO:0002930//trabecular meshwork development;GO:0043066//negative regulation of apoptotic process;GO:0061303//cornea development in camera-type eye;GO:0042789//mRNA transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:1902747//negative regulation of lens fiber cell differentiation;GO:0061072//iris morphogenesis;GO:2001111//positive regulation of lens epithelial cell proliferation;GO:0071157//negative regulation of cell cycle arrest;GO:0061073//ciliary body morphogenesis;GO:0048468//cell development;GO:0002088//lens development in camera-type eye","K09398//forkhead box protein E","NP_036318.1//forkhead box protein E3 [Homo sapiens]","2//1"]
[90381,6688,9.37,6.26,-0.581886390726568,{"v":6.23313326877193e-12,"d":"6.23E-12"},"*",{"v":5.56042e-13,"d":"5.56E-13"},"TICRR","GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0003682//chromatin binding","GO:0033314//mitotic DNA replication checkpoint;GO:0000075//cell cycle checkpoint;GO:0030174//regulation of DNA-dependent DNA replication initiation;GO:0010212//response to ionizing radiation;GO:0006281//DNA repair;GO:0006260//DNA replication;GO:0001731//formation of translation preinitiation complex","K10955//mucin-2","NP_689472.3//treslin isoform 2 [Homo sapiens];NP_001294954.1//treslin isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[7110,6895,1.81,1.21,-0.580982649808611,0.00534743973004242,"*",1.73606E-3,"TMF1","GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0000139//Golgi membrane","GO:0003677//DNA binding;GO:0003712//transcription cofactor activity","GO:0030317//flagellated sperm motility;GO:0006355//regulation of transcription, DNA-templated;GO:0007289//spermatid nucleus differentiation;GO:0010629//negative regulation of gene expression;GO:0043066//negative regulation of apoptotic process;GO:0042742//defense response to bacterium;GO:0001819//positive regulation of cytokine production;GO:0006366//transcription from RNA polymerase II promoter;GO:0061136//regulation of proteasomal protein catabolic process;GO:0001675//acrosome assembly;GO:0071407//cellular response to organic cyclic compound;GO:0033327//Leydig cell differentiation;GO:0032275//luteinizing hormone secretion;GO:2000845//positive regulation of testosterone secretion","K20286//TATA element modulatory factor","BAD92346.1//TATA element modulatory factor 1 variant, partial [Homo sapiens]","2//1"]
[5089,3231,16.07,10.75,-0.580033269198271,{"v":6.04083129760547e-10,"d":"6.04E-10"},"*",{"v":6.63304e-11,"d":"6.63E-11"},"PBX2","GO:0005634//nucleus;GO:0005667//transcription factor complex","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0008134//transcription factor binding","GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0009954//proximal/distal pattern formation;GO:0030326//embryonic limb morphogenesis","K15609//pre-B-cell leukemia transcription factor 2","NP_002577.2//pre-B-cell leukemia transcription factor 2 [Homo sapiens]",4]
[57464,4757,5.57,3.73,-0.578501697084794,{"v":2.55933820411056e-06,"d":"2.56E-06"},"*",{"v":4.52138e-07,"d":"4.52E-07"},"STRIP2","GO:0005829//cytosol;GO:0005737//cytoplasm","NA","GO:0016477//cell migration;GO:0007010//cytoskeleton organization;GO:0008360//regulation of cell shape","K12581//CCR4-NOT transcription complex subunit 7/8","EAL24101.1//family with sequence similarity 40, member B [Homo sapiens]","1//3;2//1"]
[201895,5395,9.62,6.45,-0.576737733459425,{"v":3.10240302105263e-09,"d":"3.10E-09"},"*",{"v":3.6901E-10,"d":"3.69E-10"},"SMIM14","GO:0016021//integral component of membrane","NA","NA","K11447//histone demethylase [EC:1.14.11.-]","XP_012864548.1//PREDICTED: small integral membrane protein 14 isoform X1 [Dipodomys ordii]","1//3;2//1"]
[54585,4075,2.49,1.67,-0.576297639594029,0.0120476264423588,"*",0.00425898,"LZTFL1","GO:0005829//cytosol","GO:0042802//identical protein binding;GO:0032403//protein complex binding","GO:1903565//negative regulation of protein localization to cilium;GO:1903568//negative regulation of protein localization to ciliary membrane","K19400//leucine zipper transcription factor-like protein 1","NP_001263308.1//leucine zipper transcription factor-like protein 1 isoform 3 [Homo sapiens];XP_003257022.1//PREDICTED: leucine zipper transcription factor-like protein 1 isoform X1 [Nomascus leucogenys];XP_516411.4//PREDICTED: leucine zipper transcription factor-like protein 1 isoform X1 [Pan troglodytes]","1//3;3//A2MP1"]
[64411,5281,4.01,2.69,-0.575996063898296,0.000142789390521327,"*",{"v":3.39498e-05,"d":"3.39E-05"},"ARAP3","GO:0001726//ruffle;GO:0005856//cytoskeleton;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0030027//lamellipodium;GO:0005737//cytoplasm","GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0046872//metal ion binding;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding;GO:0005096//GTPase activator activity","GO:0007165//signal transduction;GO:0035021//negative regulation of Rac protein signal transduction;GO:0007010//cytoskeleton organization;GO:0030336//negative regulation of cell migration;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0008360//regulation of cell shape;GO:0035024//negative regulation of Rho protein signal transduction;GO:0016192//vesicle-mediated transport","K12490//Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3","NP_071926.4//arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 [Homo sapiens]",5]
[115209,1953,5.51,3.7,-0.574527048054845,0.00990272183433025,"*",0.00342014,"OMA1","GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane","GO:0046872//metal ion binding;GO:0004222//metalloendopeptidase activity","GO:0006006//glucose metabolic process;GO:0042407//cristae formation;GO:0002024//diet induced thermogenesis;GO:0006950//response to stress;GO:0010637//negative regulation of mitochondrial fusion;GO:0097009//energy homeostasis;GO:0006515//protein quality control for misfolded or incompletely synthesized proteins;GO:0034982//mitochondrial protein processing;GO:0042981//regulation of apoptotic process;GO:0006629//lipid metabolic process","K11865//protein MYSM1","NP_660286.1//metalloendopeptidase OMA1, mitochondrial precursor [Homo sapiens]",4]
[51141,2659,2.56,1.72,-0.573735245297902,0.0325802989496786,"*",0.0130105,"INSIG2","GO:0032937//SREBP-SCAP-Insig complex;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0008134//transcription factor binding","GO:0008203//cholesterol metabolic process;GO:0006641//triglyceride metabolic process;GO:0032868//response to insulin;GO:0010894//negative regulation of steroid biosynthetic process;GO:0006695//cholesterol biosynthetic process;GO:0032933//SREBP signaling pathway;GO:0060363//cranial suture morphogenesis;GO:0006991//response to sterol depletion;GO:0042472//inner ear morphogenesis;GO:0042474//middle ear morphogenesis;GO:0045717//negative regulation of fatty acid biosynthetic process;GO:0060021//palate development;GO:0070542//response to fatty acid","NA","NP_057217.2//insulin-induced gene 2 protein isoform a [Homo sapiens];AAD43048.1//insulin induced protein 2 [Homo sapiens];XP_017355724.1//PREDICTED: insulin-induced gene 2 protein isoform X5 [Cebus capucinus imitator];XP_004004796.2//PREDICTED: LOW QUALITY PROTEIN: insulin-induced gene 2 protein isoform X1 [Ovis aries]","1//3;3//A2MP1"]
[57546,7117,4.42,2.97,-0.573583438590666,{"v":3.49470396536197e-06,"d":"3.49E-06"},"*",{"v":6.31602e-07,"d":"6.32E-07"},"PDP2","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0046872//metal ion binding;GO:0004741//[pyruvate dehydrogenase (lipoamide)] phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity","GO:0010510//regulation of acetyl-CoA biosynthetic process from pyruvate","K01102//pyruvate dehydrogenase phosphatase [EC:3.1.3.43]","NP_065837.1//[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial precursor [Homo sapiens];XP_007991796.1//PREDICTED: [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial isoform X1 [Chlorocebus sabaeus]","1//3;3//A2MP1"]
[10721,8787,2.29,1.54,-0.572417247402043,0.000251239846301439,"*",{"v":6.22988e-05,"d":"6.23E-05"},"POLQ","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0005524//ATP binding;GO:0051575//5'-deoxyribose-5-phosphate lyase activity;GO:0042802//identical protein binding;GO:0043142//single-stranded DNA-dependent ATPase activity;GO:0003887//DNA-directed DNA polymerase activity;GO:0003684//damaged DNA binding;GO:0003682//chromatin binding","GO:0006281//DNA repair;GO:0006284//base-excision repair;GO:0016446//somatic hypermutation of immunoglobulin genes;GO:0051260//protein homooligomerization;GO:0006302//double-strand break repair;GO:2000042//negative regulation of double-strand break repair via homologous recombination;GO:0006261//DNA-dependent DNA replication;GO:0097681//double-strand break repair via alternative nonhomologous end joining;GO:0000724//double-strand break repair via homologous recombination;GO:0006974//cellular response to DNA damage stimulus","K02349//DNA polymerase theta [EC:2.7.7.7]","EAW79510.1//polymerase (DNA directed), theta, isoform CRA_a [Homo sapiens]","3//A2MP1"]
[5738,6319,6.18,4.16,-0.571023309763282,{"v":1.33595772550364e-07,"d":"1.34E-07"},"*",{"v":1.951164e-08,"d":"1.95E-08"},"PTGFRN","GO:0009986//cell surface;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane","NA","GO:0034389//lipid particle organization","K06729//prostaglandin F2 receptor negative regulator","NP_065173.2//prostaglandin F2 receptor negative regulator precursor [Homo sapiens]","3//A2MP1"]
[210,3238,8.55,5.76,-0.569855608330948,{"v":1.4788825768262E-5,"d":"1.48E-05"},"*",{"v":2.94036E-6,"d":"2.94E-06"},"ALAD","GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005829//cytosol;GO:1904813//ficolin-1-rich granule lumen;GO:0005576//extracellular region;GO:0005839//proteasome core complex","GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0008270//zinc ion binding;GO:1904854//proteasome core complex binding;GO:0003824//catalytic activity;GO:0004655//porphobilinogen synthase activity","GO:0010044//response to aluminum ion;GO:0043200//response to amino acid;GO:0032496//response to lipopolysaccharide;GO:0051260//protein homooligomerization;GO:0006779//porphyrin-containing compound biosynthetic process;GO:0045471//response to ethanol;GO:0006783//heme biosynthetic process;GO:0033197//response to vitamin E;GO:0010269//response to selenium ion;GO:0043312//neutrophil degranulation;GO:0046685//response to arsenic-containing substance;GO:0071353//cellular response to interleukin-4;GO:0051384//response to glucocorticoid;GO:1901799//negative regulation of proteasomal protein catabolic process;GO:0010266//response to vitamin B1;GO:0042493//response to drug;GO:0010212//response to ionizing radiation;GO:0014823//response to activity;GO:0006782//protoporphyrinogen IX biosynthetic process;GO:0010043//response to zinc ion;GO:0010039//response to iron ion;GO:0009635//response to herbicide;GO:0001666//response to hypoxia;GO:0071284//cellular response to lead ion;GO:0006979//response to oxidative stress;GO:0046686//response to cadmium ion;GO:0032025//response to cobalt ion;GO:0046689//response to mercury ion;GO:0051597//response to methylmercury;GO:0070542//response to fatty acid;GO:0070541//response to platinum ion","K01698//porphobilinogen synthase [EC:4.2.1.24]","XP_007966544.1//PREDICTED: delta-aminolevulinic acid dehydratase isoform X1 [Chlorocebus sabaeus];XP_003911382.1//delta-aminolevulinic acid dehydratase isoform X1 [Papio anubis]","1//3;2//1;5"]
[249,2332,0.46,0.31,-0.569365645670138,0.372419825105783,"*",0.231416,"ALPL","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0031225//anchored component of membrane;GO:0005578//proteinaceous extracellular matrix;GO:0065010//extracellular membrane-bounded organelle;GO:0005576//extracellular region;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0046872//metal ion binding;GO:0016462//pyrophosphatase activity;GO:0004035//alkaline phosphatase activity","GO:0001958//endochondral ossification;GO:0001649//osteoblast differentiation;GO:0006501//C-terminal protein lipidation;GO:0003006//developmental process involved in reproduction;GO:0032496//response to lipopolysaccharide;GO:0071529//cementum mineralization;GO:0033280//response to vitamin D;GO:0046677//response to antibiotic;GO:0071407//cellular response to organic cyclic compound;GO:0001501//skeletal system development;GO:0051384//response to glucocorticoid","K01077//alkaline phosphatase [EC:3.1.3.1]","NP_001170991.1//alkaline phosphatase, tissue-nonspecific isozyme isoform 3 [Homo sapiens];BAD93051.1//ALPL protein variant, partial [Homo sapiens]","3//A2MP1;2//1;5"]
[80267,6670,2.7,1.82,-0.569020956852135,0.000602274779583236,"*",0.0001610314,"EDEM3","GO:0016020//membrane;GO:0005788//endoplasmic reticulum lumen;GO:0005783//endoplasmic reticulum;GO:0044322//endoplasmic reticulum quality control compartment","GO:0004571//mannosyl-oligosaccharide 1,2-alpha-mannosidase activity;GO:0005509//calcium ion binding","GO:0006486//protein glycosylation;GO:1904382//mannose trimming involved in glycoprotein ERAD pathway;GO:0006491//N-glycan processing;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0097466//ubiquitin-dependent glycoprotein ERAD pathway","K10086//ER degradation enhancer, mannosidase alpha-like 3","NP_079467.3//ER degradation-enhancing alpha-mannosidase-like protein 3 isoform 2 precursor [Homo sapiens];NP_001306889.1//ER degradation-enhancing alpha-mannosidase-like protein 3 isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[55793,3518,3.41,2.3,-0.568137878079797,0.0154976943614458,"*",0.00563676,"MINDY1","GO:0070062//extracellular exosome","GO:0036435//K48-linked polyubiquitin modification-dependent protein binding;GO:0004843//thiol-dependent ubiquitin-specific protease activity;GO:0016807//cysteine-type carboxypeptidase activity;GO:1990380//Lys48-specific deubiquitinase activity","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K01064//wingless-type MMTV integration site family, member 9;K12025//tripartite motif-containing protein 52","NP_001156730.1//ubiquitin carboxyl-terminal hydrolase MINDY-1 isoform 3 [Homo sapiens];NP_060849.2//ubiquitin carboxyl-terminal hydrolase MINDY-1 isoform 1 [Homo sapiens]","4;1//3;2//1"]
[10184,5061,13.84,9.34,-0.567349487927063,{"v":1.03602083141361E-12,"d":"1.04E-12"},"*",{"v":8.67134e-14,"d":"8.67E-14"},"LHFPL2","GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0031092//platelet alpha granule membrane","NA","GO:0046545//development of primary female sexual characteristics;GO:0002576//platelet degranulation;GO:1905516//positive regulation of fertilization;GO:0046546//development of primary male sexual characteristics;GO:0007338//single fertilization","NA","NP_005770.1//lipoma HMGIC fusion partner-like 2 protein [Homo sapiens]","2//1"]
[23221,5053,13.05,8.81,-0.566835882536833,{"v":8.9751265870923e-12,"d":"8.98E-12"},"*",{"v":8.09638e-13,"d":"8.10E-13"},"RHOBTB2","GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0007264//small GTPase mediated signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction","K07868//Rho-related BTB domain-containing protein 1/2","NP_001153509.1//rho-related BTB domain-containing protein 2 isoform 2 [Homo sapiens];XP_002756887.2//PREDICTED: rho-related BTB domain-containing protein 2 isoform X1 [Callithrix jacchus];NP_001153508.1//rho-related BTB domain-containing protein 2 isoform 1 [Homo sapiens]","1//3;2//1"]
[84656,3684,27.78,18.77,-0.565617949150518,{"v":1.5140933625498e-16,"d":"1.51E-16"},"*",{"v":9.5164e-18,"d":"9.52E-18"},"GLYR1","NA","NA","NA","K00020//3-hydroxyisobutyrate dehydrogenase [EC:1.1.1.31];K15195//AF4/FMR2 family member 3;K18121//glyoxylate/succinic semialdehyde reductase [EC:1.1.1.79 1.1.1.-]","XP_003815153.2//PREDICTED: putative oxidoreductase GLYR1 isoform X1 [Pan paniscus];XP_007982801.1//PREDICTED: LOW QUALITY PROTEIN: putative oxidoreductase GLYR1 [Chlorocebus sabaeus];XP_017361512.1//PREDICTED: putative oxidoreductase GLYR1 isoform X6 [Cebus capucinus imitator];XP_017361511.1//PREDICTED: putative oxidoreductase GLYR1 isoform X5 [Cebus capucinus imitator];XP_003815154.1//PREDICTED: putative oxidoreductase GLYR1 isoform X3 [Pan paniscus]","1//3;3//A2MP1"]
[91828,2591,1.05,0.71,-0.564498398161441,0.26250705779043,"*",0.1500862,"EXOC3L4","GO:0000145//exocyst","GO:0000149//SNARE binding","GO:0051601//exocyst localization;GO:0006887//exocytosis","K19988//exocyst complex component 3-like protein 2;K06110//exocyst complex component 3","XP_011535635.1//PREDICTED: exocyst complex component 3-like protein 4 isoform X3 [Homo sapiens]","1//3"]
[23252,6523,2.07,1.4,-0.564203940554359,0.00313331833663366,"*",0.000970752,"OTUD3","NA","NA","NA","K13717//OTU domain-containing protein 3 [EC:3.4.19.12]","XP_513073.6//PREDICTED: OTU domain-containing protein 3 isoform X1 [Pan troglodytes]","1//3"]
[90993,2741,0.99,0.67,-0.563267429621837,0.262478318239545,"*",0.1500862,"CREB3L1","GO:0016020//membrane;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0003682//chromatin binding;GO:0035497//cAMP response element binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0046332//SMAD binding;GO:0003700//DNA binding transcription factor activity;GO:0044212//transcription regulatory region DNA binding","GO:0001649//osteoblast differentiation;GO:0032967//positive regulation of collagen biosynthetic process;GO:1990440//positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress;GO:0070278//extracellular matrix constituent secretion;GO:0007275//multicellular organism development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0030968//endoplasmic reticulum unfolded protein response;GO:1902236//negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway","K09048//cyclic AMP-responsive element-binding protein 3","NP_443086.1//cyclic AMP-responsive element-binding protein 3-like protein 1 [Homo sapiens]","3//A2MP1"]
[85460,6936,1.18,0.8,-0.560714954474479,0.026604700860319,"*",0.01033776,"ZNF518B","GO:0005634//nucleus","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003676//nucleic acid binding","GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","NP_444270.2//zinc finger protein 518B [Homo sapiens]","2//1"]
[57489,4323,7.05,4.78,-0.560612639305407,{"v":6.10467969836503e-06,"d":"6.10E-06"},"*",{"v":1.145344E-6,"d":"1.15E-06"},"ODF2L","GO:0005813//centrosome","NA","NA","K16479//outer dense fiber protein 2","NP_001171694.1//outer dense fiber protein 2-like isoform c [Homo sapiens];NP_001171695.1//outer dense fiber protein 2-like isoform d [Homo sapiens];NP_001007023.2//outer dense fiber protein 2-like isoform b [Homo sapiens];NP_065780.2//outer dense fiber protein 2-like isoform a [Homo sapiens]","1//3;2//1"]
[2009,4479,11.16,7.57,-0.559971821843456,{"v":4.06300848648649e-09,"d":"4.06E-09"},"*",{"v":4.89372e-10,"d":"4.89E-10"},"EML1","NA","NA","NA","K18595//echinoderm microtubule-associated protein-like 1/2","XP_001367603.1//PREDICTED: echinoderm microtubule-associated protein-like 1 isoform X4 [Monodelphis domestica];XP_001367643.1//PREDICTED: echinoderm microtubule-associated protein-like 1 isoform X7 [Monodelphis domestica]","1//3;2//1"]
[3087,1772,14.86,10.09,-0.558507941432239,{"v":3.67539570672098e-05,"d":"3.68E-05"},"*",{"v":7.90806e-06,"d":"7.91E-06"},"HHEX","GO:0005634//nucleus;GO:0032993//protein-DNA complex;GO:0005737//cytoplasm","GO:0071837//HMG box domain binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0070491//repressing transcription factor binding;GO:0044212//transcription regulatory region DNA binding;GO:0042803//protein homodimerization activity;GO:0001227//transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0008190//eukaryotic initiation factor 4E binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0017025//TBP-class protein binding;GO:0043565//sequence-specific DNA binding;GO:0008134//transcription factor binding;GO:0008301//DNA binding, bending","GO:0042127//regulation of cell proliferation;GO:0048853//forebrain morphogenesis;GO:0030878//thyroid gland development;GO:0016973//poly(A)+ mRNA export from nucleus;GO:0001570//vasculogenesis;GO:0009611//response to wounding;GO:0045892//negative regulation of transcription, DNA-templated;GO:0007492//endoderm development;GO:0030154//cell differentiation;GO:0060431//primary lung bud formation;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0035264//multicellular organism growth;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0016055//Wnt signaling pathway;GO:0007219//Notch signaling pathway;GO:0071103//DNA conformation change;GO:0009952//anterior/posterior pattern specification;GO:0006406//mRNA export from nucleus;GO:0010944//negative regulation of transcription by competitive promoter binding;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0090009//primitive streak formation;GO:0008283//cell proliferation;GO:0061017//hepatoblast differentiation;GO:0030948//negative regulation of vascular endothelial growth factor receptor signaling pathway;GO:0030183//B cell differentiation;GO:0070365//hepatocyte differentiation;GO:0016525//negative regulation of angiogenesis;GO:0043434//response to peptide hormone;GO:0006351//transcription, DNA-templated;GO:0001701//in utero embryonic development;GO:0035050//embryonic heart tube development;GO:0002573//myeloid leukocyte differentiation;GO:0031016//pancreas development;GO:0030177//positive regulation of Wnt signaling pathway;GO:0061010//gall bladder development;GO:0010621//negative regulation of transcription by transcription factor localization;GO:0061011//hepatic duct development;GO:0034504//protein localization to nucleus;GO:0022027//interkinetic nuclear migration","K08024//homeobox protein HEX","XP_003783831.1//PREDICTED: hematopoietically-expressed homeobox protein HHEX [Otolemur garnettii]",4]
[586,9303,1.62,1.1,-0.558490289359965,0.00202064538108279,"*",0.000600476,"BCAT1","GO:0005829//cytosol;GO:0005739//mitochondrion","GO:0052654//L-leucine transaminase activity;GO:0004084//branched-chain-amino-acid transaminase activity;GO:0052656//L-isoleucine transaminase activity;GO:0042802//identical protein binding;GO:0052655//L-valine transaminase activity","GO:0009099//valine biosynthetic process;GO:0009098//leucine biosynthetic process;GO:0009083//branched-chain amino acid catabolic process;GO:0008283//cell proliferation;GO:0000082//G1/S transition of mitotic cell cycle;GO:0009082//branched-chain amino acid biosynthetic process","K00826//branched-chain amino acid aminotransferase [EC:2.6.1.42]","NP_001171565.1//branched-chain-amino-acid aminotransferase, cytosolic isoform 5 [Homo sapiens];XP_016875257.1//PREDICTED: branched-chain-amino-acid aminotransferase, cytosolic isoform X1 [Homo sapiens];XP_001143074.3//PREDICTED: branched-chain-amino-acid aminotransferase, cytosolic isoform X1 [Pan troglodytes]","6;1//3"]
[643853,3714,0.5,0.34,-0.556393348524385,0.399180063829787,"*",0.25839,"TMPPE","GO:0016021//integral component of membrane","GO:0046872//metal ion binding;GO:0016787//hydrolase activity","NA","K10457//kelch-like protein 20;K12309//beta-galactosidase [EC:3.2.1.23]","NP_001034859.2//transmembrane protein with metallophosphoesterase domain isoform 1 [Homo sapiens]","1//3;2//1"]
[5066,5130,3.1,2.11,-0.555025216567053,0.00167849560908701,"*",0.000490288,"PAM","GO:0000793//condensed chromosome;GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0030667//secretory granule membrane;GO:0000790//nuclear chromatin;GO:0005802//trans-Golgi network;GO:0048471//perinuclear region of cytoplasm;GO:0043204//perikaryon;GO:0043005//neuron projection;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004504//peptidylglycine monooxygenase activity;GO:0031418//L-ascorbic acid binding;GO:0019901//protein kinase binding;GO:0004598//peptidylamidoglycolate lyase activity;GO:0005509//calcium ion binding;GO:0005507//copper ion binding;GO:0003682//chromatin binding;GO:0008270//zinc ion binding","GO:0018032//protein amidation;GO:0007595//lactation;GO:0060135//maternal process involved in female pregnancy;GO:0009404//toxin metabolic process;GO:0051260//protein homooligomerization;GO:0032956//regulation of actin cytoskeleton organization;GO:0007076//mitotic chromosome condensation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0032355//response to estradiol;GO:0051384//response to glucocorticoid;GO:0001519//peptide amidation;GO:0042476//odontogenesis;GO:0022602//ovulation cycle process;GO:0042493//response to drug;GO:0009268//response to pH;GO:0007507//heart development;GO:0007417//central nervous system development;GO:0001676//long-chain fatty acid metabolic process;GO:0046688//response to copper ion;GO:0001666//response to hypoxia;GO:0060173//limb development;GO:0050708//regulation of protein secretion","K00504//peptidylglycine monooxygenase [EC:1.14.17.3];K18200//peptidylamidoglycolate lyase [EC:4.3.2.5]","NP_620121.1//peptidyl-glycine alpha-amidating monooxygenase isoform b precursor [Homo sapiens];NP_620177.1//peptidyl-glycine alpha-amidating monooxygenase isoform d precursor [Homo sapiens];NP_000910.2//peptidyl-glycine alpha-amidating monooxygenase isoform a precursor [Homo sapiens];NP_001170777.1//peptidyl-glycine alpha-amidating monooxygenase isoform e preproprotein [Homo sapiens];NP_620176.1//peptidyl-glycine alpha-amidating monooxygenase isoform c precursor [Homo sapiens];NP_001306872.1//peptidyl-glycine alpha-amidating monooxygenase isoform f precursor [Homo sapiens]","1//3;3//A2MP1;2//1"]
[54813,6577,1.19,0.81,-0.554967760423319,0.0336923418397626,"*",0.0135052,"KLHL28","GO:0031463//Cul3-RING ubiquitin ligase complex","NA","GO:0016567//protein ubiquitination","K10464//kelch-like protein 28","NP_001295041.1//kelch-like protein 28 isoform 1 [Homo sapiens]","4;1//3"]
[221322,5134,0.69,0.47,-0.553935605100532,0.200602963412633,"*",0.1071582,"TBC1D32","GO:0005929//cilium;GO:0005737//cytoplasm","NA","GO:0060831//smoothened signaling pathway involved in dorsal/ventral neural tube patterning;GO:0003406//retinal pigment epithelium development;GO:0007368//determination of left/right symmetry;GO:0007507//heart development;GO:1905515//non-motile cilium assembly;GO:0061512//protein localization to cilium;GO:0002088//lens development in camera-type eye;GO:0042733//embryonic digit morphogenesis","K12581//CCR4-NOT transcription complex subunit 7/8;K01368//cathepsin S [EC:3.4.22.27];K04135//adrenergic receptor alpha-1A;K20636//Rho GTPase-activating protein 12/27;K10477//BTB/POZ domain-containing protein 1/2","NP_689943.4//protein broad-minded [Homo sapiens]",5]
[57609,8715,5.43,3.7,-0.553426927288049,{"v":1.3049425542192E-8,"d":"1.30E-08"},"*",{"v":1.684482E-9,"d":"1.68E-09"},"DIP2B","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0003824//catalytic activity","GO:0008152//metabolic process","K05637//laminin, alpha 1/2;K05747//Wiskott-Aldrich syndrome protein;K06274//vasodilator-stimulated phosphoprotein","XP_004429071.1//PREDICTED: disco-interacting protein 2 homolog B isoform X2 [Ceratotherium simum simum]","2//1"]
[84340,3258,14.04,9.57,-0.552952105818535,{"v":2.5610166895902e-08,"d":"2.56E-08"},"*",{"v":3.40368E-9,"d":"3.40E-09"},"GFM2","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0003746//translation elongation factor activity;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0032543//mitochondrial translation;GO:0070126//mitochondrial translational termination;GO:0032790//ribosome disassembly","K02355//elongation factor G","NP_001268231.1//ribosome-releasing factor 2, mitochondrial isoform 4 [Homo sapiens];NP_733781.1//ribosome-releasing factor 2, mitochondrial isoform 3 [Homo sapiens];NP_733792.1//ribosome-releasing factor 2, mitochondrial isoform 2 [Homo sapiens]","4;1//3;2//1"]
[10746,10870,3.59,2.45,-0.551202094820481,{"v":3.87084891011236E-7,"d":"3.87E-07"},"*",{"v":6.03866e-08,"d":"6.04E-08"},"MAP3K2","GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0004709//MAP kinase kinase kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0019901//protein kinase binding","GO:0007346//regulation of mitotic cell cycle;GO:0071260//cellular response to mechanical stimulus;GO:0000187//activation of MAPK activity;GO:0006468//protein phosphorylation;GO:0042981//regulation of apoptotic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0007257//activation of JUN kinase activity","K04420//mitogen-activated protein kinase kinase kinase 2 [EC:2.7.11.25]","XP_007122724.1//PREDICTED: LOW QUALITY PROTEIN: mitogen-activated protein kinase kinase kinase 2 [Physeter catodon]",4]
[10905,8606,2.08,1.42,-0.55069259863641,0.000875606497737557,"*",0.00024228,"MAN1A2","GO:0070062//extracellular exosome;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0004571//mannosyl-oligosaccharide 1,2-alpha-mannosidase activity;GO:0005509//calcium ion binding","GO:0007585//respiratory gaseous exchange;GO:0009100//glycoprotein metabolic process;GO:0008152//metabolic process;GO:0048286//lung alveolus development","K01230//mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]","XP_003933576.1//PREDICTED: mannosyl-oligosaccharide 1,2-alpha-mannosidase IB [Saimiri boliviensis boliviensis]",4]
[6646,6933,8.87,6.06,-0.549616310828113,{"v":8.00697761012658e-11,"d":"8.01E-11"},"*",{"v":7.91976e-12,"d":"7.92E-12"},"SOAT1","GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0004772//sterol O-acyltransferase activity;GO:0015485//cholesterol binding;GO:0000062//fatty-acyl-CoA binding;GO:0034736//cholesterol O-acyltransferase activity","GO:0034383//low-density lipoprotein particle clearance;GO:0042986//positive regulation of amyloid precursor protein biosynthetic process;GO:0010878//cholesterol storage;GO:0008203//cholesterol metabolic process;GO:0034435//cholesterol esterification;GO:0033344//cholesterol efflux;GO:0034379//very-low-density lipoprotein particle assembly;GO:0010742//macrophage derived foam cell differentiation;GO:0042632//cholesterol homeostasis","K00637//sterol O-acyltransferase [EC:2.3.1.26]","NP_001239440.1//sterol O-acyltransferase 1 isoform 2 [Homo sapiens];NP_003092.4//sterol O-acyltransferase 1 isoform 1 [Homo sapiens]","1//3;5"]
[3720,5981,3.35,2.29,-0.548813497248191,{"v":9.32441299425759e-05,"d":"9.32E-05"},"*",{"v":2.13468E-5,"d":"2.13E-05"},"JARID2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0035097//histone methyltransferase complex;GO:0005739//mitochondrion;GO:0035098//ESC/E(Z) complex","GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0008134//transcription factor binding;GO:0001227//transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0060044//negative regulation of cardiac muscle cell proliferation;GO:0001889//liver development;GO:0048538//thymus development;GO:0006351//transcription, DNA-templated;GO:0051574//positive regulation of histone H3-K9 methylation;GO:0007417//central nervous system development;GO:0048863//stem cell differentiation;GO:0010614//negative regulation of cardiac muscle hypertrophy;GO:1990830//cellular response to leukemia inhibitory factor;GO:0048536//spleen development;GO:0016569//covalent chromatin modification;GO:0045814//negative regulation of gene expression, epigenetic;GO:0031061//negative regulation of histone methylation;GO:0008285//negative regulation of cell proliferation","K11478//protein Jumonji","NP_004964.2//protein Jumonji isoform 1 [Homo sapiens];XP_016866322.1//PREDICTED: protein Jumonji isoform X2 [Homo sapiens]","1//3;3//A2MP1"]
[146198,4655,3.48,2.38,-0.548125732540785,0.000551408180541814,"*",1.465336E-4,"ZFP90","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0043392//negative regulation of DNA binding;GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein;K09230//SCAN domain-containing zinc finger protein","XP_012926981.1//zinc finger protein 90 homolog isoform X2 [Heterocephalus glaber];NP_001292133.1//zinc finger protein 90 homolog isoform 2 [Homo sapiens];XP_003998236.1//PREDICTED: zinc finger protein 90 homolog isoform X2 [Felis catus]","1//3;3//A2MP1"]
[100506012,1257,0.19,0.13,-0.547487795302493,0.782151852820003,"*",0.689316,"PPP5D1","NA","NA","NA","K04460//serine/threonine-protein phosphatase 5 [EC:3.1.3.16]","NP_001192210.1//protein PPP5D1 [Homo sapiens]","1//3"]
[81846,7447,3.96,2.71,-0.547207578725738,{"v":1.4027947892575E-5,"d":"1.40E-05"},"*",{"v":2.77942e-06,"d":"2.78E-06"},"SBF2","GO:0005774//vacuolar membrane;GO:0016020//membrane;GO:0005829//cytosol","GO:0019902//phosphatase binding;GO:0017112//Rab guanyl-nucleotide exchange factor activity;GO:0042803//protein homodimerization activity;GO:0019208//phosphatase regulator activity;GO:0035091//phosphatidylinositol binding","GO:0042552//myelination;GO:0043087//regulation of GTPase activity;GO:0051262//protein tetramerization;GO:0061024//membrane organization","K18061//myotubularin-related protein 5/13","XP_003818195.1//PREDICTED: myotubularin-related protein 13 isoform X3 [Pan paniscus]","3//A2MP1"]
[23483,1980,2.98,2.04,-0.546743178490666,0.0862596,"*",0.0394686,"TGDS","NA","GO:0008460//dTDP-glucose 4,6-dehydratase activity","NA","K01710//dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]","XP_006211070.1//PREDICTED: dTDP-D-glucose 4,6-dehydratase [Vicugna pacos];NP_055120.1//dTDP-D-glucose 4,6-dehydratase isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[284353,4687,0.54,0.37,-0.545434136534519,0.241301762683905,"*",0.1355302,"NKPD1","NA","NA","NA","K12460//ankyrin repeat-rich membrane spanning protein;K18167//succinate dehydrogenase assembly factor 1","XP_011525101.1//PREDICTED: NTPase KAP family P-loop domain-containing protein 1 isoform X1 [Homo sapiens]","3//A2MP1"]
[79879,1343,1.94,1.33,-0.544630406685938,0.304600263164611,"*",0.1793202,"CCDC134","GO:0016020//membrane;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005576//extracellular region","NA","NA","K19501//anoctamin-7","XP_011710499.1//PREDICTED: coiled-coil domain-containing protein 134 isoform X3 [Macaca nemestrina];XP_005567186.1//PREDICTED: coiled-coil domain-containing protein 134 isoform X1 [Macaca fascicularis]","1//3;3//A2MP1"]
[7046,6449,6.18,4.24,-0.543542573341175,{"v":1.66902992648923E-7,"d":"1.67E-07"},"*",{"v":2.47314E-8,"d":"2.47E-08"},"TGFBR1","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005622//intracellular;GO:0043235//receptor complex;GO:0005768//endosome;GO:0009986//cell surface;GO:0045121//membrane raft;GO:0005623//cell;GO:0005923//bicellular tight junction;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005025//transforming growth factor beta receptor activity, type I;GO:0005057//signal transducer activity, downstream of receptor;GO:0005524//ATP binding;GO:0005114//type II transforming growth factor beta receptor binding;GO:0046872//metal ion binding;GO:0004672//protein kinase activity;GO:0070411//I-SMAD binding;GO:0004702//signal transducer, downstream of receptor, with serine/threonine kinase activity;GO:0004675//transmembrane receptor protein serine/threonine kinase activity;GO:0050431//transforming growth factor beta binding","GO:1905075//positive regulation of occluding junction disassembly;GO:0060412//ventricular septum morphogenesis;GO:0030335//positive regulation of cell migration;GO:0060317//cardiac epithelial to mesenchymal transition;GO:0010717//regulation of epithelial to mesenchymal transition;GO:0030199//collagen fibril organization;GO:0008354//germ cell migration;GO:0008584//male gonad development;GO:0060978//angiogenesis involved in coronary vascular morphogenesis;GO:0009791//post-embryonic development;GO:0003223//ventricular compact myocardium morphogenesis;GO:0001837//epithelial to mesenchymal transition;GO:0002088//lens development in camera-type eye;GO:0000186//activation of MAPKK activity;GO:0031396//regulation of protein ubiquitination;GO:0001937//negative regulation of endothelial cell proliferation;GO:0043393//regulation of protein binding;GO:0043542//endothelial cell migration;GO:0060017//parathyroid gland development;GO:0007507//heart development;GO:0060037//pharyngeal system development;GO:0032924//activin receptor signaling pathway;GO:0010628//positive regulation of gene expression;GO:2001235//positive regulation of apoptotic signaling pathway;GO:0018107//peptidyl-threonine phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0048663//neuron fate commitment;GO:1905223//epicardium morphogenesis;GO:0003222//ventricular trabecula myocardium morphogenesis;GO:0009952//anterior/posterior pattern specification;GO:0051897//positive regulation of protein kinase B signaling;GO:0010468//regulation of gene expression;GO:0001822//kidney development;GO:0030307//positive regulation of cell growth;GO:0035556//intracellular signal transduction;GO:0045893//positive regulation of transcription, DNA-templated;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0001824//blastocyst development;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:1905007//positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation;GO:0001938//positive regulation of endothelial cell proliferation;GO:0060021//palate development;GO:0060043//regulation of cardiac muscle cell proliferation;GO:0070723//response to cholesterol;GO:0051491//positive regulation of filopodium assembly;GO:0060982//coronary artery morphogenesis;GO:0060391//positive regulation of SMAD protein import into nucleus;GO:0048538//thymus development;GO:0051496//positive regulation of stress fiber assembly;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0032331//negative regulation of chondrocyte differentiation;GO:0060389//pathway-restricted SMAD protein phosphorylation;GO:0042118//endothelial cell activation;GO:0008284//positive regulation of cell proliferation;GO:0048762//mesenchymal cell differentiation","K04674//TGF-beta receptor type-1 [EC:2.7.11.30]","NP_001293139.1//TGF-beta receptor type-1 isoform 3 precursor [Homo sapiens];XP_007966794.1//PREDICTED: TGF-beta receptor type-1 isoform X3 [Chlorocebus sabaeus];NP_004603.1//TGF-beta receptor type-1 isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1;2//1"]
[25942,6674,15.94,10.95,-0.541720759501936,{"v":1.36255447939262E-17,"d":"1.36E-17"},"*",{"v":7.8645e-19,"d":"7.86E-19"},"SIN3A","GO:0017053//transcriptional repressor complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005667//transcription factor complex;GO:0016580//Sin3 complex;GO:0000776//kinetochore","GO:0003723//RNA binding;GO:0001103//RNA polymerase II repressing transcription factor binding;GO:0033558//protein deacetylase activity;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0001106//RNA polymerase II transcription corepressor activity;GO:0003682//chromatin binding;GO:0001102//RNA polymerase II activating transcription factor binding;GO:0003700//DNA binding transcription factor activity;GO:0032403//protein complex binding","GO:2000678//negative regulation of transcription regulatory region DNA binding;GO:0042754//negative regulation of circadian rhythm;GO:0002244//hematopoietic progenitor cell differentiation;GO:0006260//DNA replication;GO:0002218//activation of innate immune response;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0031937//positive regulation of chromatin silencing;GO:0043619//regulation of transcription from RNA polymerase II promoter in response to oxidative stress;GO:0019216//regulation of lipid metabolic process;GO:1901675//negative regulation of histone H3-K27 acetylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0001701//in utero embryonic development;GO:0043066//negative regulation of apoptotic process;GO:0048511//rhythmic process;GO:0051595//response to methylglyoxal;GO:0045652//regulation of megakaryocyte differentiation;GO:0007568//aging;GO:0071333//cellular response to glucose stimulus;GO:1903351//cellular response to dopamine;GO:0010817//regulation of hormone levels;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0010971//positive regulation of G2/M transition of mitotic cell cycle;GO:0034613//cellular protein localization;GO:1900181//negative regulation of protein localization to nucleus;GO:0016575//histone deacetylation;GO:0002230//positive regulation of defense response to virus by host;GO:0006476//protein deacetylation","K11644//paired amphipathic helix protein Sin3a","XP_016782697.1//PREDICTED: paired amphipathic helix protein Sin3a isoform X1 [Pan troglodytes]","1//3;2//1"]
[56833,2973,0.16,0.11,-0.540568381362703,0.670110212105063,"*",0.551014,"SLAMF8","GO:0016021//integral component of membrane","NA","NA","K16853//SLAM family member 8","NP_064510.1//SLAM family member 8 isoform 1 precursor [Homo sapiens];NP_001317670.1//SLAM family member 8 isoform 2 [Homo sapiens]","1//3;2//1"]
[286006,1480,0.16,0.11,-0.540568381362703,0.781541187025339,"*",0.689316,"LSMEM1","GO:0005829//cytosol;GO:0016021//integral component of membrane","NA","NA","NA","NP_872403.1//leucine-rich single-pass membrane protein 1 [Homo sapiens];XP_011811322.1//PREDICTED: leucine-rich single-pass membrane protein 1 isoform X1 [Colobus angolensis palliatus]","1//3;2//1"]
[64770,4211,8.94,6.15,-0.539688420956715,{"v":8.97332763774734e-07,"d":"8.97E-07"},"*",{"v":1.476268e-07,"d":"1.48E-07"},"CCDC14","GO:0005813//centrosome;GO:0034451//centriolar satellite","NA","GO:0021762//substantia nigra development;GO:0071539//protein localization to centrosome","K16541//coiled-coil domain-containing protein 14","XP_005247767.1//PREDICTED: coiled-coil domain-containing protein 14 isoform X1 [Homo sapiens];XP_009444589.2//PREDICTED: coiled-coil domain-containing protein 14 isoform X2 [Pan troglodytes]","4;1//3"]
[631,2073,2.95,2.03,-0.539235227064028,0.0756867906053404,"*",0.0338918,"BFSP1","GO:0005938//cell cortex;GO:0005882//intermediate filament;GO:0005737//cytoplasm;GO:0005886//plasma membrane","GO:0005212//structural constituent of eye lens;GO:0005200//structural constituent of cytoskeleton","GO:0048469//cell maturation;GO:0070307//lens fiber cell development","K10378//filensin","NP_001265536.1//filensin isoform 4 [Homo sapiens];NP_001186.1//filensin isoform 1 [Homo sapiens]","4;1//3"]
[10052,7643,6.13,4.22,-0.538644074983596,{"v":3.42479029834254E-8,"d":"3.42E-08"},"*",{"v":4.65672E-9,"d":"4.66E-09"},"GJC1","GO:0005921//gap junction;GO:0005922//connexin complex;GO:0016021//integral component of membrane;GO:0014704//intercalated disc;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane","GO:0005216//ion channel activity;GO:0086020//gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling;GO:0086077//gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling","GO:0006810//transport;GO:0007043//cell-cell junction assembly;GO:0086053//AV node cell to bundle of His cell communication by electrical coupling;GO:0006936//muscle contraction;GO:0048738//cardiac muscle tissue development;GO:0007154//cell communication;GO:0007601//visual perception;GO:0016264//gap junction assembly;GO:0086014//atrial cardiac muscle cell action potential;GO:0007268//chemical synaptic transmission;GO:0001570//vasculogenesis;GO:0086021//SA node cell to atrial cardiac muscle cell communication by electrical coupling;GO:0048468//cell development","K07616//gap junction gamma-1 protein","NP_005488.2//gap junction gamma-1 protein [Homo sapiens]","1//3;3//A2MP1"]
[25898,4447,1.51,1.04,-0.537965021183987,0.0685483877806195,"*",0.0302018,"RCHY1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000151//ubiquitin ligase complex;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0005737//cytoplasm","GO:0002039//p53 binding;GO:0008270//zinc ion binding;GO:0005102//receptor binding;GO:0042803//protein homodimerization activity;GO:0004842//ubiquitin-protein transferase activity","GO:0070987//error-free translesion synthesis;GO:0016567//protein ubiquitination;GO:0051865//protein autoubiquitination;GO:0031398//positive regulation of protein ubiquitination;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process","K10144//RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27]","NP_001265465.1//RING finger and CHY zinc finger domain-containing protein 1 isoform 4 [Homo sapiens];XP_017732079.1//PREDICTED: RING finger and CHY zinc finger domain-containing protein 1 isoform X1 [Rhinopithecus bieti];NP_001009922.1//RING finger and CHY zinc finger domain-containing protein 1 isoform 3 [Homo sapiens];NP_001265467.1//RING finger and CHY zinc finger domain-containing protein 1 isoform 6 [Homo sapiens];NP_001265466.1//RING finger and CHY zinc finger domain-containing protein 1 isoform 5 [Homo sapiens];BAD92309.1//RING finger and CHY zinc finger domain containing protein 1 variant, partial [Homo sapiens]","1//3;3//A2MP1;2//1"]
[5205,6169,3.41,2.35,-0.537110982459173,4.51623524705882E-4,"*",1.177546E-4,"ATP8B1","GO:0005783//endoplasmic reticulum;GO:0016324//apical plasma membrane;GO:0031526//brush border membrane;GO:0005887//integral component of plasma membrane;GO:0005794//Golgi apparatus;GO:0032420//stereocilium;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0000287//magnesium ion binding;GO:1901612//cardiolipin binding;GO:0005524//ATP binding;GO:0004012//phospholipid-translocating ATPase activity;GO:0015247//aminophospholipid transmembrane transporter activity","GO:0045892//negative regulation of transcription, DNA-templated;GO:0034220//ion transmembrane transport;GO:0007030//Golgi organization;GO:0015721//bile acid and bile salt transport;GO:0021650//vestibulocochlear nerve formation;GO:0045332//phospholipid translocation;GO:0032534//regulation of microvillus assembly;GO:0007605//sensory perception of sound;GO:0060119//inner ear receptor cell development;GO:0008206//bile acid metabolic process;GO:0006855//drug transmembrane transport","K01530//phospholipid-translocating ATPase [EC:3.6.3.1]","NP_005594.1//phospholipid-transporting ATPase IC [Homo sapiens]",5]
[22834,11434,2.48,1.71,-0.536343795500977,{"v":3.79645178403483e-05,"d":"3.80E-05"},"*",{"v":8.18754e-06,"d":"8.19E-06"},"ZNF652","NA","GO:0003676//nucleic acid binding","NA","K09228//KRAB domain-containing zinc finger protein","XP_003996761.1//PREDICTED: zinc finger protein 652 [Felis catus]","1//3;2//1"]
[8793,3569,13.35,9.21,-0.535566680483581,{"v":4.1882112866242E-8,"d":"4.19E-08"},"*",{"v":5.76292e-09,"d":"5.76E-09"},"TNFRSF10D","GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane","GO:0045569//TRAIL binding;GO:0004888//transmembrane signaling receptor activity;GO:0005031//tumor necrosis factor-activated receptor activity","GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007165//signal transduction;GO:0050900//leukocyte migration;GO:0097190//apoptotic signaling pathway;GO:0042127//regulation of cell proliferation;GO:0032496//response to lipopolysaccharide;GO:0043066//negative regulation of apoptotic process;GO:0006954//inflammatory response;GO:0007275//multicellular organism development;GO:0006955//immune response;GO:0042981//regulation of apoptotic process","K04722//tumor necrosis factor receptor superfamily member 10","NP_003831.2//tumor necrosis factor receptor superfamily member 10D precursor [Homo sapiens]",4]
[4361,5150,3.97,2.74,-0.534963114182431,0.000512717614529915,"*",1.351926E-4,"MRE11","GO:0035861//site of double-strand break;GO:0016605//PML body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000784//nuclear chromosome, telomeric region;GO:0030870//Mre11 complex;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0042802//identical protein binding;GO:0000014//single-stranded DNA endodeoxyribonuclease activity;GO:0003690//double-stranded DNA binding;GO:0004518//nuclease activity;GO:0045296//cadherin binding;GO:0004520//endodeoxyribonuclease activity;GO:0008408//3'-5' exonuclease activity;GO:0008022//protein C-terminus binding;GO:0004519//endonuclease activity;GO:0030145//manganese ion binding","GO:0032481//positive regulation of type I interferon production;GO:0007095//mitotic G2 DNA damage checkpoint;GO:0031860//telomeric 3' overhang formation;GO:0006260//DNA replication;GO:0031954//positive regulation of protein autophosphorylation;GO:0032508//DNA duplex unwinding;GO:0006302//double-strand break repair;GO:0031573//intra-S DNA damage checkpoint;GO:0007131//reciprocal meiotic recombination;GO:0008283//cell proliferation;GO:0000731//DNA synthesis involved in DNA repair;GO:0051321//meiotic cell cycle;GO:0007004//telomere maintenance via telomerase;GO:0006974//cellular response to DNA damage stimulus;GO:0007129//synapsis;GO:0000732//strand displacement;GO:0006281//DNA repair;GO:0043066//negative regulation of apoptotic process;GO:0016032//viral process;GO:0032206//positive regulation of telomere maintenance;GO:1901796//regulation of signal transduction by p53 class mediator;GO:0000729//DNA double-strand break processing;GO:0000019//regulation of mitotic recombination;GO:0007062//sister chromatid cohesion;GO:0032876//negative regulation of DNA endoreduplication;GO:0033674//positive regulation of kinase activity;GO:0000724//double-strand break repair via homologous recombination;GO:0006310//DNA recombination;GO:0006303//double-strand break repair via nonhomologous end joining","K10865//double-strand break repair protein MRE11","XP_016777317.1//PREDICTED: double-strand break repair protein MRE11A isoform X1 [Pan troglodytes];NP_005581.2//double-strand break repair protein MRE11 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[200539,2591,1.97,1.36,-0.534588978206037,0.11733321610247,"*",0.0561986,"ANKRD23","GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0030016//myofibril;GO:0014704//intercalated disc","GO:0031432//titin binding","GO:0009612//response to mechanical stimulus","K21438//ankyrin repeat domain-containing protein 23","NP_659431.5//ankyrin repeat domain-containing protein 23 [Homo sapiens]",7]
[6654,8331,6.53,4.51,-0.53395555829105,{"v":3.57695750261233e-09,"d":"3.58E-09"},"*",{"v":4.2859e-10,"d":"4.29E-10"},"SOS1","NA","NA","NA","K03099//son of sevenless","DAA24733.1//TPA: son of sevenless homolog 1 [Bos taurus]","3//A2MP1"]
[255967,5643,2.59,1.79,-0.532992510422297,0.0042089775916519,"*",1.338262E-3,"PAN3","NA","NA","NA","K12572//PAB-dependent poly(A)-specific ribonuclease subunit 3","XP_003913764.2//PAB-dependent poly(A)-specific ribonuclease subunit PAN3 isoform X1 [Papio anubis]",7]
[54877,5559,2.53,1.75,-0.531782462861982,0.00495619849359721,"*",1.599114E-3,"ZCCHC2","GO:0005737//cytoplasm","GO:0008270//zinc ion binding;GO:0035091//phosphatidylinositol binding;GO:0003676//nucleic acid binding","NA","K16628//collagen, type VII, alpha;K03129//transcription initiation factor TFIID subunit 4","NP_060212.4//zinc finger CCHC domain-containing protein 2 [Homo sapiens]",5]
[51701,3555,4.42,3.06,-0.53051471669878,0.00293872888879854,"*",0.000904946,"NLK","GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005737//cytoplasm","GO:0000287//magnesium ion binding;GO:0005524//ATP binding;GO:0031625//ubiquitin protein ligase binding;GO:0042169//SH2 domain binding;GO:0004674//protein serine/threonine kinase activity;GO:0004672//protein kinase activity;GO:0004707//MAP kinase activity;GO:0008134//transcription factor binding","GO:0010468//regulation of gene expression;GO:0006355//regulation of transcription, DNA-templated;GO:0030178//negative regulation of Wnt signaling pathway;GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction;GO:0006351//transcription, DNA-templated;GO:0046777//protein autophosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0042501//serine phosphorylation of STAT protein;GO:0007223//Wnt signaling pathway, calcium modulating pathway;GO:0016055//Wnt signaling pathway;GO:0050821//protein stabilization","K04468//nemo like kinase [EC:2.7.11.24]","NP_057315.3//serine/threonine-protein kinase NLK [Homo sapiens]",4]
[3631,6427,4.81,3.33,-0.53051471669878,{"v":3.63114952725153e-05,"d":"3.63E-05"},"*",{"v":7.79922e-06,"d":"7.80E-06"},"INPP4A","GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0017161//inositol-1,3,4-trisphosphate 4-phosphatase activity;GO:0034597//phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity;GO:0052828//inositol-3,4-bisphosphate 4-phosphatase activity;GO:0016316//phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity","GO:0007165//signal transduction;GO:0043647//inositol phosphate metabolic process;GO:0006661//phosphatidylinositol biosynthetic process","K01109//inositol polyphosphate-4-phosphatase [EC:3.1.3.66]","NP_001557.1//type I inositol 3,4-bisphosphate 4-phosphatase isoform b [Homo sapiens];NP_001127696.1//type I inositol 3,4-bisphosphate 4-phosphatase isoform d [Homo sapiens];NP_004018.1//type I inositol 3,4-bisphosphate 4-phosphatase isoform a [Homo sapiens];NP_001338357.1//type I inositol 3,4-bisphosphate 4-phosphatase isoform g [Homo sapiens];NP_001127697.1//type I inositol 3,4-bisphosphate 4-phosphatase isoform c [Homo sapiens];NP_001338353.1//type I inositol 3,4-bisphosphate 4-phosphatase isoform e [Homo sapiens];NP_001338355.1//type I inositol 3,4-bisphosphate 4-phosphatase isoform f [Homo sapiens];NP_001338358.1//type I inositol 3,4-bisphosphate 4-phosphatase isoform h [Homo sapiens]","1//3;2//1"]
[5151,3876,25.61,17.73,-0.53051471669878,{"v":5.873868e-17,"d":"5.87E-17"},"*",{"v":3.57786e-18,"d":"3.58E-18"},"PDE8A","GO:0070062//extracellular exosome;GO:0005829//cytosol","GO:0046872//metal ion binding;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0019900//kinase binding;GO:0004115//3',5'-cyclic-AMP phosphodiesterase activity","GO:1903206//negative regulation of hydrogen peroxide-induced cell death;GO:0009187//cyclic nucleotide metabolic process;GO:0006198//cAMP catabolic process;GO:0007165//signal transduction;GO:0006355//regulation of transcription, DNA-templated;GO:0001934//positive regulation of protein phosphorylation;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0060548//negative regulation of cell death;GO:0071364//cellular response to epidermal growth factor stimulus","K18437//high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:3.1.4.53]","NP_002596.1//high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform 1 [Homo sapiens];NP_775656.1//high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform 2 [Homo sapiens]","1//3;2//1"]
[8505,3645,8.04,5.57,-0.529518173838897,{"v":2.4794504953868E-6,"d":"2.48E-06"},"*",{"v":4.37404e-07,"d":"4.37E-07"},"PARG","GO:0005759//mitochondrial matrix;GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0004649//poly(ADP-ribose) glycohydrolase activity","GO:1990966//ATP generation from poly-ADP-D-ribose;GO:0005975//carbohydrate metabolic process","K07759//poly(ADP-ribose) glycohydrolase [EC:3.2.1.143]","NP_001290415.1//poly(ADP-ribose) glycohydrolase isoform b [Homo sapiens];NP_003622.2//poly(ADP-ribose) glycohydrolase isoform a [Homo sapiens];NP_001290418.1//poly(ADP-ribose) glycohydrolase isoform d [Homo sapiens]","4;2//1"]
[83744,4783,0.75,0.52,-0.528378972354789,0.207860723171724,"*",0.11192,"ZNF484","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","NP_001248387.1//zinc finger protein 484 isoform c [Homo sapiens];NP_001341466.1//zinc finger protein 484 isoform d [Homo sapiens]","1//3;3//A2MP1;2//1"]
[10767,6524,6.11,4.24,-0.52710811525553,{"v":2.20896947300679e-06,"d":"2.21E-06"},"*",{"v":3.86784e-07,"d":"3.87E-07"},"HBS1L","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0005622//intracellular","GO:0003746//translation elongation factor activity;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0043928//exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay;GO:0007165//signal transduction;GO:0006412//translation","K14416//elongation factor 1 alpha-like protein","NP_006611.1//HBS1-like protein isoform 1 [Homo sapiens];NP_001138679.1//HBS1-like protein isoform 3 [Homo sapiens];NP_001138630.1//HBS1-like protein isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[5074,7554,7.82,5.43,-0.526216409502991,{"v":8.54777626106001e-08,"d":"8.55E-08"},"*",{"v":1.221646e-08,"d":"1.22E-08"},"PAWR","GO:0005884//actin filament;GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0005737//cytoplasm","GO:0003779//actin binding;GO:0003714//transcription corepressor activity;GO:0043522//leucine zipper domain binding;GO:0019899//enzyme binding","GO:1901300//positive regulation of hydrogen peroxide-mediated programmed cell death;GO:0042986//positive regulation of amyloid precursor protein biosynthetic process;GO:0097190//apoptotic signaling pathway;GO:0006351//transcription, DNA-templated;GO:0010628//positive regulation of gene expression;GO:0048147//negative regulation of fibroblast proliferation;GO:0006915//apoptotic process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0042094//interleukin-2 biosynthetic process;GO:0050860//negative regulation of T cell receptor signaling pathway;GO:2000774//positive regulation of cellular senescence;GO:0043065//positive regulation of apoptotic process;GO:0042130//negative regulation of T cell proliferation;GO:0051017//actin filament bundle assembly;GO:0030889//negative regulation of B cell proliferation","K12581//CCR4-NOT transcription complex subunit 7/8;K13172//serine/arginine repetitive matrix protein 2;K01064//wingless-type MMTV integration site family, member 9","NP_001341662.1//PRKC apoptosis WT1 regulator protein isoform 2 [Homo sapiens];NP_002574.2//PRKC apoptosis WT1 regulator protein isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[10269,3165,24.56,17.06,-0.525692914051889,{"v":3.27742413793103e-12,"d":"3.28E-12"},"*",{"v":2.856e-13,"d":"2.86E-13"},"ZMPSTE24","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005637//nuclear inner membrane","GO:0046872//metal ion binding;GO:0004222//metalloendopeptidase activity;GO:0008235//metalloexopeptidase activity","GO:0006508//proteolysis;GO:0030327//prenylated protein catabolic process;GO:0006998//nuclear envelope organization;GO:0071586//CAAX-box protein processing","K06013//STE24 endopeptidase [EC:3.4.24.84]","NP_005848.2//CAAX prenyl protease 1 homolog [Homo sapiens]",4]
[26508,4131,2.49,1.73,-0.525373704431356,0.0195166093290949,"*",0.00730254,"HEYL","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm","GO:0003714//transcription corepressor activity;GO:0046982//protein heterodimerization activity;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0050683//AF-1 domain binding;GO:0000983//transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding;GO:0042803//protein homodimerization activity;GO:0001106//RNA polymerase II transcription corepressor activity;GO:0035939//microsatellite binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0000988//transcription factor activity, protein binding;GO:0008134//transcription factor binding;GO:0003700//DNA binding transcription factor activity","GO:0060412//ventricular septum morphogenesis;GO:0045666//positive regulation of neuron differentiation;GO:0003198//epithelial to mesenchymal transition involved in endocardial cushion formation;GO:0060317//cardiac epithelial to mesenchymal transition;GO:0014031//mesenchymal cell development;GO:2000824//negative regulation of androgen receptor activity;GO:0003184//pulmonary valve morphogenesis;GO:0060766//negative regulation of androgen receptor signaling pathway;GO:0003203//endocardial cushion morphogenesis;GO:0003181//atrioventricular valve morphogenesis;GO:0072014//proximal tubule development;GO:0032835//glomerulus development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0003151//outflow tract morphogenesis;GO:0003208//cardiac ventricle morphogenesis;GO:0035914//skeletal muscle cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0071773//cellular response to BMP stimulus;GO:0007219//Notch signaling pathway","K09091//hairy and enhancer of split related with YRPW motif","NP_055386.1//hairy/enhancer-of-split related with YRPW motif-like protein [Homo sapiens]","3//A2MP1"]
[10457,2764,1.05,0.73,-0.524420958786106,0.283747183382019,"*",0.164184,"GPNMB","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0042470//melanosome;GO:0005886//plasma membrane","GO:0045545//syndecan binding;GO:0005178//integrin binding;GO:0048018//receptor ligand activity;GO:0008201//heparin binding;GO:0042056//chemoattractant activity","GO:1901215//negative regulation of neuron death;GO:0001649//osteoblast differentiation;GO:0030335//positive regulation of cell migration;GO:0032720//negative regulation of tumor necrosis factor production;GO:0031954//positive regulation of protein autophosphorylation;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle;GO:0042130//negative regulation of T cell proliferation;GO:0034103//regulation of tissue remodeling;GO:0001934//positive regulation of protein phosphorylation;GO:0001818//negative regulation of cytokine production;GO:0008285//negative regulation of cell proliferation;GO:0030282//bone mineralization;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0007155//cell adhesion;GO:0045765//regulation of angiogenesis;GO:0050868//negative regulation of T cell activation;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0050918//positive chemotaxis","K20732//transmembrane glycoprotein NMB","BAG65446.1//unnamed protein product [Homo sapiens];NP_002501.1//transmembrane glycoprotein NMB isoform b precursor [Homo sapiens]","1//3;2//1"]
[84733,4161,12.64,8.79,-0.524061393033699,{"v":5.39041527258383e-07,"d":"5.39E-07"},"*",{"v":8.55434e-08,"d":"8.55E-08"},"CBX2","GO:0035102//PRC1 complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031519//PcG protein complex;GO:0000791//euchromatin;GO:0000792//heterochromatin","GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0035064//methylated histone binding","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0030154//cell differentiation;GO:0016569//covalent chromatin modification;GO:0006351//transcription, DNA-templated;GO:0045137//development of primary sexual characteristics","K11451//chromobox protein 2","NP_005180.1//chromobox protein homolog 2 isoform 1 [Homo sapiens];NP_116036.1//chromobox protein homolog 2 isoform 2 [Homo sapiens]","3//A2MP1;2//1"]
[83903,2797,10.68,7.43,-0.523477531148958,{"v":3.04684425340438E-5,"d":"3.05E-05"},"*",{"v":6.44312e-06,"d":"6.44E-06"},"HASPIN","GO:0005634//nucleus;GO:0005819//spindle;GO:0005813//centrosome;GO:0005694//chromosome;GO:0005737//cytoplasm","GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0072354//histone kinase activity (H3-T3 specific)","GO:2000751//histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore;GO:0071459//protein localization to chromosome, centromeric region;GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction;GO:0007064//mitotic sister chromatid cohesion","K16315//serine/threonine-protein kinase haspin [EC:2.7.11.1]","NP_114171.2//serine/threonine-protein kinase haspin [Homo sapiens]","2//1"]
[11127,6277,5.3,3.69,-0.522371543390165,{"v":9.39153988181818e-06,"d":"9.39E-06"},"*",{"v":1.810814e-06,"d":"1.81E-06"},"KIF3A","NA","NA","NA","K10394//kinesin family member 3A","XP_008989605.1//PREDICTED: kinesin-like protein KIF3A isoform X5 [Callithrix jacchus];XP_002744651.2//PREDICTED: kinesin-like protein KIF3A isoform X1 [Callithrix jacchus];XP_008989602.1//PREDICTED: kinesin-like protein KIF3A isoform X4 [Callithrix jacchus]","6;1//3"]
[83648,4093,4.09,2.85,-0.521138923889645,0.00250494663107801,"*",0.000757882,"FAM167A","NA","NA","NA","NA","XP_017739197.1//PREDICTED: protein FAM167A isoform X2 [Rhinopithecus bieti]","2//1"]
[25966,6349,2.18,1.52,-0.520256811333341,0.00666115498205177,"*",2.20718E-3,"C2CD2","GO:0005634//nucleus;GO:0005829//cytosol;GO:0016021//integral component of membrane","NA","NA","K22069//LYR motif-containing protein 4;K01368//cathepsin S [EC:3.4.22.27];K03129//transcription initiation factor TFIID subunit 4;K17985//activating molecule in BECN1-regulated autophagy protein 1;K02184//formin 2","NP_056315.1//C2 domain-containing protein 2 isoform 1 [Homo sapiens]","1//3;2//1"]
[23509,5160,23.27,16.23,-0.519808210857377,{"v":1.28653132075472E-20,"d":"1.29E-20"},"*",{"v":5.976e-22,"d":"5.98E-22"},"POFUT1","GO:0016020//membrane;GO:0005783//endoplasmic reticulum","GO:0008417//fucosyltransferase activity;GO:0046922//peptide-O-fucosyltransferase activity","GO:0008593//regulation of Notch signaling pathway;GO:0007399//nervous system development;GO:0001525//angiogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0007507//heart development;GO:0016266//O-glycan processing;GO:0006493//protein O-linked glycosylation;GO:0001756//somitogenesis;GO:0009790//embryo development;GO:0006004//fucose metabolic process;GO:0007219//Notch signaling pathway;GO:0036066//protein O-linked fucosylation","K03691//peptide-O-fucosyltransferase [EC:2.4.1.221]","NP_758436.1//GDP-fucose protein O-fucosyltransferase 1 isoform 2 precursor [Homo sapiens];NP_056167.1//GDP-fucose protein O-fucosyltransferase 1 isoform 1 precursor [Homo sapiens]","1//3"]
[138639,4527,1.59,1.11,-0.518467088934249,0.0578395488324873,"*",0.0249658,"PTPDC1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm","GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity","GO:0060271//cilium assembly;GO:0007224//smoothened signaling pathway","K18078//protein tyrosine phosphatase domain-containing protein 1 [EC:3.1.3.-]","NP_001240758.1//protein tyrosine phosphatase domain-containing protein 1 isoform 3 [Homo sapiens];NP_818931.1//protein tyrosine phosphatase domain-containing protein 1 isoform 2 [Homo sapiens];NP_001240759.1//protein tyrosine phosphatase domain-containing protein 1 isoform 4 [Homo sapiens];NP_689635.3//protein tyrosine phosphatase domain-containing protein 1 isoform 1 [Homo sapiens]","4;1//3;2//1"]
[84940,2386,6,4.19,-0.518012256796529,0.00621916623553954,"*",0.00205294,"CORO6","GO:0015629//actin cytoskeleton","GO:0051015//actin filament binding","GO:0030036//actin cytoskeleton organization","K13886//coronin-1B/1C/6","XP_001137500.1//PREDICTED: coronin-6 isoform X1 [Pan troglodytes];NP_001338231.1//coronin-6 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[23705,4332,7.68,5.37,-0.516184222735744,{"v":1.55261280375587e-05,"d":"1.55E-05"},"*",{"v":3.10542e-06,"d":"3.11E-06"},"CADM1","GO:0070062//extracellular exosome;GO:0016323//basolateral plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005913//cell-cell adherens junction;GO:0005911//cell-cell junction;GO:0016021//integral component of membrane;GO:0045202//synapse;GO:0005886//plasma membrane","GO:0050839//cell adhesion molecule binding;GO:0004872//receptor activity;GO:0005102//receptor binding;GO:0030165//PDZ domain binding;GO:0042803//protein homodimerization activity","GO:0030154//cell differentiation;GO:0007283//spermatogenesis;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0042271//susceptibility to natural killer cell mediated cytotoxicity;GO:0051606//detection of stimulus;GO:0006915//apoptotic process;GO:0034332//adherens junction organization;GO:0002376//immune system process;GO:0007275//multicellular organism development;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0050715//positive regulation of cytokine secretion;GO:0008037//cell recognition","K06781//cell adhesion molecule 1","NP_055148.3//cell adhesion molecule 1 isoform D precursor [Homo sapiens];NP_001287973.1//cell adhesion molecule 1 isoform B precursor [Homo sapiens];XP_003952094.1//PREDICTED: cell adhesion molecule 1 isoform X1 [Pan troglodytes];NP_001091987.1//cell adhesion molecule 1 isoform E precursor [Homo sapiens];NP_001287974.1//cell adhesion molecule 1 isoform C precursor [Homo sapiens]","1//3;3//A2MP1"]
[23443,5803,3.23,2.26,-0.515211392278737,0.00153629617522659,"*",0.000445674,"SLC35A3","NA","NA","NA","K15272//solute carrier family 35 (UDP-sugar transporter), member A1/2/3","XP_003784169.2//PREDICTED: UDP-N-acetylglucosamine transporter [Otolemur garnettii];XP_005542670.1//PREDICTED: UDP-N-acetylglucosamine transporter isoform X1 [Macaca fascicularis];XP_017720626.1//PREDICTED: UDP-N-acetylglucosamine transporter [Rhinopithecus bieti]","1//3;2//1"]
[51304,9463,8.16,5.71,-0.515078406608653,{"v":2.4875843991584E-5,"d":"2.49E-05"},"*",{"v":5.18104e-06,"d":"5.18E-06"},"ZDHHC3","GO:0016020//membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0016409//palmitoyltransferase activity;GO:0019706//protein-cysteine S-palmitoyltransferase activity","GO:0006605//protein targeting;GO:0018345//protein palmitoylation","K20029//palmitoyltransferase ZDHHC3/7/25 [EC:2.3.1.225]","XP_007982106.1//PREDICTED: palmitoyltransferase ZDHHC3 isoform X7 [Chlorocebus sabaeus];NP_001336306.1//palmitoyltransferase ZDHHC3 isoform 6 [Homo sapiens];NP_057682.1//palmitoyltransferase ZDHHC3 isoform 2 [Homo sapiens];NP_001336305.1//palmitoyltransferase ZDHHC3 isoform 5 [Homo sapiens];XP_011532099.1//PREDICTED: palmitoyltransferase ZDHHC3 isoform X2 [Homo sapiens];NP_001128651.1//palmitoyltransferase ZDHHC3 isoform 1 [Homo sapiens];NP_001317690.1//palmitoyltransferase ZDHHC3 isoform 4 [Homo sapiens]","1//3;2//1"]
[11213,8168,0.2,0.14,-0.514573172829758,0.463031673174794,"*",0.313258,"IRAK3","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0000287//magnesium ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity","GO:0032494//response to peptidoglycan;GO:0043407//negative regulation of MAP kinase activity;GO:0010933//positive regulation of macrophage tolerance induction;GO:0042177//negative regulation of protein catabolic process;GO:0032715//negative regulation of interleukin-6 production;GO:0032695//negative regulation of interleukin-12 production;GO:0032496//response to lipopolysaccharide;GO:0043330//response to exogenous dsRNA;GO:0032720//negative regulation of tumor necrosis factor production;GO:0070498//interleukin-1-mediated signaling pathway;GO:0034122//negative regulation of toll-like receptor signaling pathway;GO:0010936//negative regulation of macrophage cytokine production;GO:0070555//response to interleukin-1;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0001960//negative regulation of cytokine-mediated signaling pathway;GO:0045824//negative regulation of innate immune response;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0006468//protein phosphorylation;GO:0043242//negative regulation of protein complex disassembly;GO:0046777//protein autophosphorylation;GO:0043244//regulation of protein complex disassembly;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0019221//cytokine-mediated signaling pathway;GO:0009615//response to virus","K04732//interleukin-1 receptor-associated kinase 3 [EC:2.7.11.1]","NP_009130.2//interleukin-1 receptor-associated kinase 3 isoform a [Homo sapiens];NP_001135995.1//interleukin-1 receptor-associated kinase 3 isoform b [Homo sapiens]","1//3;2//1"]
[378708,1243,9.28,6.5,-0.513685087211755,0.0188104048454301,"*",0.00700886,"CENPS","GO:0000776//kinetochore;GO:0043240//Fanconi anaemia nuclear complex;GO:0071821//FANCM-MHF complex","GO:0003682//chromatin binding;GO:0046982//protein heterodimerization activity;GO:0003690//double-stranded DNA binding","GO:0000712//resolution of meiotic recombination intermediates;GO:0006281//DNA repair;GO:0031297//replication fork processing;GO:0051382//kinetochore assembly","K11511//centromere protein S","XP_003274282.1//PREDICTED: centromere protein S [Nomascus leucogenys]","2//1"]
[79647,2719,23.95,16.78,-0.513282940183719,{"v":5.37508575172414e-10,"d":"5.38E-10"},"*",{"v":5.85492e-11,"d":"5.85E-11"},"AKIRIN1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K17776//metaxin;K11447//histone demethylase [EC:1.14.11.-];K01064//wingless-type MMTV integration site family, member 9","NP_078871.1//akirin-1 isoform 1 [Homo sapiens];NP_001129747.1//akirin-1 isoform 2 [Homo sapiens]","1//3;2//1"]
[1954,11167,9.4,6.59,-0.512382291556948,{"v":1.20752920903104E-15,"d":"1.21E-15"},"*",{"v":8.03558e-17,"d":"8.04E-17"},"MEGF8","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0016021//integral component of membrane","GO:0005509//calcium ion binding","GO:0010468//regulation of gene expression;GO:0055113//epiboly involved in gastrulation with mouth forming second;GO:0003143//embryonic heart tube morphogenesis;GO:0071907//determination of digestive tract left/right asymmetry;GO:0097155//fasciculation of sensory neuron axon;GO:0030509//BMP signaling pathway;GO:0035108//limb morphogenesis;GO:0030326//embryonic limb morphogenesis;GO:0061371//determination of heart left/right asymmetry;GO:0048704//embryonic skeletal system morphogenesis;GO:0060971//embryonic heart tube left/right pattern formation;GO:0048842//positive regulation of axon extension involved in axon guidance;GO:0097094//craniofacial suture morphogenesis;GO:0060972//left/right pattern formation;GO:0042074//cell migration involved in gastrulation;GO:0060976//coronary vasculature development","K16628//collagen, type VII, alpha;K22020//mucin-19","BAA32469.2//MEGF8, partial [Homo sapiens];NP_001258867.1//multiple epidermal growth factor-like domains protein 8 isoform 1 precursor [Homo sapiens]","1//3;2//1"]
[23729,3838,9.81,6.88,-0.511844571517141,{"v":4.15885795141977e-06,"d":"4.16E-06"},"*",{"v":7.61008e-07,"d":"7.61E-07"},"SHPK","GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0005524//ATP binding;GO:0016773//phosphotransferase activity, alcohol group as acceptor;GO:0050277//sedoheptulokinase activity","GO:0016310//phosphorylation;GO:0071222//cellular response to lipopolysaccharide;GO:0043030//regulation of macrophage activation;GO:0050727//regulation of inflammatory response;GO:0006098//pentose-phosphate shunt;GO:0009052//pentose-phosphate shunt, non-oxidative branch;GO:0005975//carbohydrate metabolic process;GO:0071353//cellular response to interleukin-4;GO:0035963//cellular response to interleukin-13","K11214//sedoheptulokinase [EC:2.7.1.14]","NP_037408.2//sedoheptulokinase [Homo sapiens]","2//1"]
[56261,5478,4.96,3.48,-0.511252814538147,{"v":9.65455313693399e-05,"d":"9.65E-05"},"*",{"v":2.2157e-05,"d":"2.22E-05"},"GPCPD1","GO:0005829//cytosol;GO:0005737//cytoplasm","GO:2001070//starch binding;GO:0047389//glycerophosphocholine phosphodiesterase activity;GO:0008889//glycerophosphodiester phosphodiesterase activity","GO:0030643//cellular phosphate ion homeostasis;GO:0007519//skeletal muscle tissue development;GO:0046475//glycerophospholipid catabolic process","K18695//glycerophosphocholine phosphodiesterase GPCPD1 [EC:3.1.4.2]","NP_062539.1//glycerophosphocholine phosphodiesterase GPCPD1 [Homo sapiens]","3//A2MP1"]
[388531,2894,0.47,0.33,-0.510194732319184,0.520343732904264,"*",0.36441,"RGS9BP","GO:0016021//integral component of membrane;GO:0001750//photoreceptor outer segment","NA","GO:0050908//detection of light stimulus involved in visual perception;GO:0009968//negative regulation of signal transduction","K03129//transcription initiation factor TFIID subunit 4;K13172//serine/arginine repetitive matrix protein 2;K06568//mucin-1","NP_997274.2//regulator of G-protein signaling 9-binding protein [Homo sapiens]","2//1"]
[8888,6198,11.49,8.07,-0.509738219368333,{"v":9.4511862778127E-11,"d":"9.45E-11"},"*",{"v":9.41332e-12,"d":"9.41E-12"},"MCM3AP","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005643//nuclear pore;GO:0031965//nuclear membrane;GO:0005829//cytosol","GO:0003677//DNA binding;GO:0016746//transferase activity, transferring acyl groups;GO:0003676//nucleic acid binding","GO:0002376//immune system process;GO:0006606//protein import into nucleus;GO:0051028//mRNA transport","K16734//SAC3 domain-containing protein 1;K07945//ADP-ribosylation factor-like protein 4","NP_003897.2//germinal-center associated nuclear protein [Homo sapiens]",4]
[80856,7548,3.7,2.6,-0.509013647487857,{"v":5.59686989807475e-05,"d":"5.60E-05"},"*",{"v":1.23752E-5,"d":"1.24E-05"},"LNPK","GO:0005654//nucleoplasm;GO:0005783//endoplasmic reticulum;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0098826//endoplasmic reticulum tubular network membrane;GO:0005789//endoplasmic reticulum membrane","GO:0046872//metal ion binding;GO:0042802//identical protein binding","GO:1903373//positive regulation of endoplasmic reticulum tubular network organization;GO:0060173//limb development;GO:0007596//blood coagulation;GO:0071788//endoplasmic reticulum tubular network maintenance;GO:0032330//regulation of chondrocyte differentiation;GO:0035115//embryonic forelimb morphogenesis;GO:0042733//embryonic digit morphogenesis","K17776//metaxin;K11447//histone demethylase [EC:1.14.11.-];K01064//wingless-type MMTV integration site family, member 9","NP_001291938.1//protein lunapark isoform 2 [Homo sapiens];NP_001291937.1//protein lunapark isoform 1 precursor [Homo sapiens];CAH56306.1//hypothetical protein, partial [Homo sapiens];NP_001291939.1//protein lunapark isoform 3 precursor [Homo sapiens];NP_085153.1//protein lunapark isoform 4 [Homo sapiens]","1//3;2//1"]
[25833,3013,0.64,0.45,-0.508146903670325,0.413793209257842,"*",0.270854,"POU2F3","GO:0005634//nucleus","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0008544//epidermis development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0043922//negative regulation by host of viral transcription","K09364//POU domain transcription factor, class 2","XP_008019405.1//PREDICTED: POU domain, class 2, transcription factor 3 [Chlorocebus sabaeus];NP_001231611.1//POU domain, class 2, transcription factor 3 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[4076,5328,67.62,47.56,-0.507701301147721,{"v":2.2623142159292e-50,"d":"2.26E-50"},"*",{"v":3.20072e-52,"d":"3.20E-52"},"CAPRIN1","GO:0016020//membrane;GO:0030425//dendrite;GO:0010494//cytoplasmic stress granule;GO:0005887//integral component of plasma membrane;GO:0005829//cytosol;GO:0000932//P-body","GO:0003723//RNA binding","GO:0050775//positive regulation of dendrite morphogenesis;GO:0017148//negative regulation of translation;GO:0061003//positive regulation of dendritic spine morphogenesis","K18743//caprin-1","XP_014970037.1//PREDICTED: caprin-1 isoform X1 [Macaca mulatta]","4;2//1"]
[399473,5075,2.77,1.95,-0.506411852299578,0.00855633652862139,"*",0.00291014,"SPRED3","GO:0016020//membrane","NA","GO:0007275//multicellular organism development;GO:0009966//regulation of signal transduction","K04703//sprouty-related, EVH1 domain-containing protein","XP_021786753.1//LOW QUALITY PROTEIN: sprouty-related, EVH1 domain-containing protein 3 [Papio anubis]","2//1"]
[11254,4579,0.44,0.31,-0.505235308250422,0.363739873808075,"*",0.224474,"SLC6A14","GO:0070062//extracellular exosome;GO:0005887//integral component of plasma membrane;GO:0031526//brush border membrane;GO:0016021//integral component of membrane;GO:0031982//vesicle;GO:0005886//plasma membrane","GO:0005328//neurotransmitter:sodium symporter activity;GO:0005215//transporter activity;GO:0015171//amino acid transmembrane transporter activity","GO:0006810//transport;GO:0006865//amino acid transport;GO:0006520//cellular amino acid metabolic process;GO:0009636//response to toxic substance","K05038//solute carrier family 6 (neurotransmitter transporter, amino acid) member 5/7/9/14","NP_009162.1//sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) [Homo sapiens]",4]
[114907,6763,1.49,1.05,-0.504923002796039,0.0426835689968321,"*",0.01771312,"FBXO32","GO:0005654//nucleoplasm;GO:0030018//Z disc;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0019005//SCF ubiquitin ligase complex","GO:0004842//ubiquitin-protein transferase activity","GO:0043687//post-translational protein modification;GO:0014894//response to denervation involved in regulation of muscle adaptation;GO:0016567//protein ubiquitination;GO:0000209//protein polyubiquitination;GO:0071549//cellular response to dexamethasone stimulus","K10305//F-box protein 25/32","XP_007999672.1//PREDICTED: F-box only protein 32 [Chlorocebus sabaeus];NP_001229392.1//F-box only protein 32 isoform 3 [Homo sapiens];AAI00021.1//FBXO32 protein, partial [Homo sapiens]","1//3;3//A2MP1;2//1"]
[54821,4380,5.5,3.88,-0.503374966224894,0.000278366014196451,"*",{"v":6.97222e-05,"d":"6.97E-05"},"ERCC6L","GO:0016020//membrane;GO:0005829//cytosol;GO:0000777//condensed chromosome kinetochore","GO:0003677//DNA binding;GO:0005524//ATP binding;GO:0004386//helicase activity","GO:0007062//sister chromatid cohesion;GO:0051301//cell division","K20093//DNA excision repair protein ERCC-6-like [EC:3.6.4.12]","NP_060139.2//DNA excision repair protein ERCC-6-like isoform a [Homo sapiens]","3//A2MP1;2//1"]
[345557,7739,0.17,0.12,-0.502500340529183,0.520436776039338,"*",0.36441,"PLCXD3","NA","NA","NA","K13749//solute carrier family 24 (sodium/potassium/calcium exchanger), member 1;K01027//3-oxoacid CoA-transferase [EC:2.8.3.5]","XP_019604115.1//PREDICTED: PI-PLC X domain-containing protein 3 [Rhinolophus sinicus]","2//1"]
[9697,7065,13.43,9.48,-0.502500340529183,{"v":1.03459614232331E-13,"d":"1.03E-13"},"*",{"v":7.97288e-15,"d":"7.97E-15"},"TRAM2","GO:0016021//integral component of membrane","NA","GO:0015031//protein transport;GO:0045048//protein insertion into ER membrane;GO:0032964//collagen biosynthetic process","K14010//translocating chain-associated membrane protein 1","NP_036420.1//translocating chain-associated membrane protein 2 [Homo sapiens]","3//A2MP1"]
[23307,4336,10.45,7.38,-0.501810220907849,{"v":5.32290018957346e-07,"d":"5.32E-07"},"*",{"v":8.4372e-08,"d":"8.44E-08"},"FKBP15","GO:0016020//membrane;GO:0030424//axon;GO:0005884//actin filament;GO:0030426//growth cone;GO:0005769//early endosome","GO:0003779//actin binding","GO:0010923//negative regulation of phosphatase activity;GO:0006897//endocytosis","K17478//FK506-binding protein 15","NP_056073.1//FK506-binding protein 15 [Homo sapiens]","1//3"]
[79923,2055,2.59,1.83,-0.501108449402511,0.125338930942861,"*",0.0608334,"NANOG","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0010468//regulation of gene expression;GO:0001714//endodermal cell fate specification;GO:0030154//cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0035019//somatic stem cell population maintenance;GO:0008283//cell proliferation;GO:0019827//stem cell population maintenance;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045595//regulation of cell differentiation","K10164//homeobox protein Nanog","NP_001284627.1//homeobox protein NANOG isoform 2 [Homo sapiens];NP_079141.2//homeobox protein NANOG isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[84529,2738,5.6,3.96,-0.499926396865357,0.0052292940947226,"*",1.693448E-3,"C15orf41","NA","NA","NA","NA","NP_001308687.1//uncharacterized protein C15orf41 isoform 5 [Homo sapiens];EAW92338.1//chromosome 15 open reading frame 41, isoform CRA_c [Homo sapiens];XP_016783402.1//PREDICTED: uncharacterized protein C15orf41 homolog isoform X4 [Pan troglodytes];XP_016783404.1//PREDICTED: uncharacterized protein C15orf41 homolog isoform X6 [Pan troglodytes];XP_016783401.1//PREDICTED: uncharacterized protein C15orf41 homolog isoform X3 [Pan troglodytes];XP_017395001.1//PREDICTED: uncharacterized protein C15orf41 homolog isoform X2 [Cebus capucinus imitator];NP_001123482.1//uncharacterized protein C15orf41 isoform 1 [Homo sapiens]","1//3;2//1;5"]
[63979,10412,3.59,2.54,-0.499155347050885,{"v":1.84047857371097e-06,"d":"1.84E-06"},"*",{"v":3.17308e-07,"d":"3.17E-07"},"FIGNL1","GO:0000228//nuclear chromosome;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm","GO:0000287//magnesium ion binding;GO:0016787//hydrolase activity;GO:0005524//ATP binding","GO:0046034//ATP metabolic process;GO:0001649//osteoblast differentiation;GO:0033687//osteoblast proliferation;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0010569//regulation of double-strand break repair via homologous recombination;GO:0007140//male meiotic nuclear division;GO:0071479//cellular response to ionizing radiation;GO:0051726//regulation of cell cycle","K13254//spastin [EC:3.6.4.3]","NP_071399.2//fidgetin-like protein 1 isoform 1 [Homo sapiens]","1//3;3//A2MP1;2//1;5"]
[22909,4659,6.44,4.56,-0.498026863949875,{"v":3.12275928440908e-05,"d":"3.12E-05"},"*",{"v":6.63298e-06,"d":"6.63E-06"},"FAN1","GO:0045171//intercellular bridge;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol","GO:0000287//magnesium ion binding;GO:0008409//5'-3' exonuclease activity;GO:0070336//flap-structured DNA binding;GO:0140036//ubiquitin-dependent protein binding;GO:0004528//phosphodiesterase I activity;GO:0017108//5'-flap endonuclease activity","GO:0006281//DNA repair;GO:0036297//interstrand cross-link repair;GO:0000724//double-strand break repair via homologous recombination;GO:0033683//nucleotide-excision repair, DNA incision;GO:0006289//nucleotide-excision repair","K15363//fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]","NP_001139566.1//fanconi-associated nuclease 1 isoform b [Homo sapiens];NP_055782.3//fanconi-associated nuclease 1 isoform a [Homo sapiens]","1//3;4"]
[91754,6252,9.02,6.39,-0.497311502308387,{"v":9.01078096421471e-09,"d":"9.01E-09"},"*",{"v":1.13495e-09,"d":"1.13E-09"},"NEK9","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005813//centrosome","GO:0046872//metal ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0019901//protein kinase binding","GO:0007077//mitotic nuclear envelope disassembly;GO:0051301//cell division","K20878//NIMA (never in mitosis gene a)-related kinase 9 [EC:2.7.11.1]","NP_149107.4//serine/threonine-protein kinase Nek9 isoform 2 [Homo sapiens];NP_001316166.1//serine/threonine-protein kinase Nek9 isoform 1 [Homo sapiens]","1//3;5"]
[7565,2746,1.89,1.34,-0.4961532337633,0.142014888677831,"*",0.0711408,"ZNF17","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","NP_008890.2//zinc finger protein 17 isoform 2 [Homo sapiens];NP_001317546.1//zinc finger protein 17 isoform 1 [Homo sapiens]","1//3;2//1"]
[9927,4653,24.17,17.14,-0.495850363653083,{"v":8.37432770313987e-16,"d":"8.37E-16"},"*",{"v":5.50984e-17,"d":"5.51E-17"},"MFN2","GO:0015630//microtubule cytoskeleton;GO:0016021//integral component of membrane;GO:0005741//mitochondrial outer membrane;GO:0031306//intrinsic component of mitochondrial outer membrane","GO:0031625//ubiquitin protein ligase binding;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0061734//parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0046580//negative regulation of Ras protein signal transduction;GO:0051646//mitochondrion localization;GO:0007006//mitochondrial membrane organization;GO:0048593//camera-type eye morphogenesis;GO:0006626//protein targeting to mitochondrion;GO:0008053//mitochondrial fusion;GO:0034497//protein localization to phagophore assembly site;GO:0001825//blastocyst formation","K06030//mitofusin 2 [EC:3.6.5.-]","XP_011725122.1//PREDICTED: mitofusin-2 [Macaca nemestrina]","1//3;3//A2MP1"]
[92017,8183,1.24,0.88,-0.494764691749578,0.0277966540490306,"*",0.01086008,"SNX29","GO:0070062//extracellular exosome","GO:0035091//phosphatidylinositol binding","NA","K17935//sorting nexin-29","EAW85124.1//hCG2042874, isoform CRA_a, partial [Homo sapiens]",4]
[3622,2465,3.79,2.69,-0.494591675614468,0.0409069111724556,"*",0.01688364,"ING2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016602//CCAAT-binding factor complex;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016580//Sin3 complex;GO:0005886//plasma membrane","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0035064//methylated histone binding;GO:0032403//protein complex binding;GO:0035091//phosphatidylinositol binding","GO:0007141//male meiosis I;GO:0006355//regulation of transcription, DNA-templated;GO:0040008//regulation of growth;GO:2001020//regulation of response to DNA damage stimulus;GO:0007283//spermatogenesis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0031065//positive regulation of histone deacetylation;GO:2001234//negative regulation of apoptotic signaling pathway;GO:0008285//negative regulation of cell proliferation;GO:0030317//flagellated sperm motility;GO:0007165//signal transduction;GO:0006351//transcription, DNA-templated;GO:0007286//spermatid development;GO:0048133//male germ-line stem cell asymmetric division;GO:1902166//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0016569//covalent chromatin modification;GO:0072520//seminiferous tubule development;GO:2000772//regulation of cellular senescence;GO:0042981//regulation of apoptotic process;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway","K19198//inhibitor of growth protein 2","NP_001555.1//inhibitor of growth protein 2 isoform 1 [Homo sapiens];NP_001278888.1//inhibitor of growth protein 2 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[54892,4114,18.62,13.22,-0.494130896051102,{"v":2.474628184E-11,"d":"2.47E-11"},"*",{"v":2.32374E-12,"d":"2.32E-12"},"NCAPG2","GO:0016020//membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000796//condensin complex;GO:0016607//nuclear speck","GO:0035064//methylated histone binding","GO:0030261//chromosome condensation;GO:0001833//inner cell mass cell proliferation;GO:0051301//cell division;GO:0007049//cell cycle","K11492//condensin-2 complex subunit G2","NP_001268862.1//condensin-2 complex subunit G2 isoform b [Homo sapiens];NP_060230.5//condensin-2 complex subunit G2 isoform a [Homo sapiens]","6;1//3"]
[255738,3731,3.32,2.36,-0.492396381985084,0.0168115041214603,"*",0.00616934,"PCSK9","GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005770//late endosome;GO:1990667//PCSK9-AnxA2 complex;GO:0005764//lysosome;GO:0048471//perinuclear region of cytoplasm;GO:0030134//COPII-coated ER to Golgi transport vesicle;GO:0009986//cell surface;GO:1990666//PCSK9-LDLR complex;GO:0005886//plasma membrane;GO:0005769//early endosome","GO:0004252//serine-type endopeptidase activity;GO:0003723//RNA binding;GO:0030169//low-density lipoprotein particle binding;GO:0034185//apolipoprotein binding;GO:0070326//very-low-density lipoprotein particle receptor binding;GO:0043621//protein self-association;GO:0034190//apolipoprotein receptor binding;GO:0019871//sodium channel inhibitor activity;GO:0030547//receptor inhibitor activity;GO:0050750//low-density lipoprotein particle receptor binding;GO:0034189//very-low-density lipoprotein particle binding","GO:0007041//lysosomal transport;GO:0001822//kidney development;GO:0008203//cholesterol metabolic process;GO:0009267//cellular response to starvation;GO:0002092//positive regulation of receptor internalization;GO:1905598//negative regulation of low-density lipoprotein receptor activity;GO:0042632//cholesterol homeostasis;GO:2000650//negative regulation of sodium ion transmembrane transporter activity;GO:0042157//lipoprotein metabolic process;GO:0032802//low-density lipoprotein particle receptor catabolic process;GO:1905601//negative regulation of receptor-mediated endocytosis involved in cholesterol transport;GO:0016540//protein autoprocessing;GO:0043525//positive regulation of neuron apoptotic process;GO:0010989//negative regulation of low-density lipoprotein particle clearance;GO:0030182//neuron differentiation;GO:0001889//liver development;GO:0006641//triglyceride metabolic process;GO:0001920//negative regulation of receptor recycling;GO:0032805//positive regulation of low-density lipoprotein particle receptor catabolic process;GO:0032869//cellular response to insulin stimulus;GO:0006644//phospholipid metabolic process;GO:1905596//negative regulation of low-density lipoprotein particle receptor binding","K13050//proprotein convertase subtilisin/kexin type 9 [EC:3.4.21.-]","XP_003815030.1//PREDICTED: proprotein convertase subtilisin/kexin type 9 isoform X2 [Pan paniscus]","3//A2MP1"]
[57379,2815,0.9,0.64,-0.491853096329675,0.36172376119403,"*",0.223026,"AICDA","GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0000178//exosome (RNase complex)","GO:0016814//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines;GO:0042802//identical protein binding;GO:0004126//cytidine deaminase activity;GO:0008270//zinc ion binding;GO:0031625//ubiquitin protein ligase binding","GO:0006397//mRNA processing;GO:0045190//isotype switching;GO:0016446//somatic hypermutation of immunoglobulin genes;GO:0080111//DNA demethylation;GO:0071222//cellular response to lipopolysaccharide;GO:0042742//defense response to bacterium;GO:0016445//somatic diversification of immunoglobulins;GO:0090310//negative regulation of methylation-dependent chromatin silencing;GO:0097752//regulation of DNA stability;GO:0030183//B cell differentiation","K10989//activation-induced cytidine deaminase [EC:3.5.4.38]","NP_001317272.1//single-stranded DNA cytosine deaminase isoform 2 [Homo sapiens];NP_065712.1//single-stranded DNA cytosine deaminase isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[7410,4750,9.67,6.88,-0.491107324774743,{"v":6.86136175609756e-07,"d":"6.86E-07"},"*",{"v":1.109484E-7,"d":"1.11E-07"},"VAV2","GO:0005829//cytosol;GO:0005622//intracellular;GO:0005737//cytoplasm;GO:0005886//plasma membrane","GO:0046872//metal ion binding;GO:0001784//phosphotyrosine residue binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005154//epidermal growth factor receptor binding;GO:0005089//Rho guanyl-nucleotide exchange factor activity","GO:0030032//lamellipodium assembly;GO:0010468//regulation of gene expression;GO:0016477//cell migration;GO:0035556//intracellular signal transduction;GO:0030168//platelet activation;GO:0030193//regulation of blood coagulation;GO:0043065//positive regulation of apoptotic process;GO:0007264//small GTPase mediated signal transduction;GO:0001525//angiogenesis;GO:0007165//signal transduction;GO:0008361//regulation of cell size;GO:0048013//ephrin receptor signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0043087//regulation of GTPase activity;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0035023//regulation of Rho protein signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction","K05730//guanine nucleotide exchange factor VAV","NP_003362.2//guanine nucleotide exchange factor VAV2 isoform 2 [Homo sapiens];NP_001127870.1//guanine nucleotide exchange factor VAV2 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[160335,4346,0.66,0.47,-0.489805267680816,0.161566933852898,"*",0.0830592,"TMTC2","GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","NA","GO:0055074//calcium ion homeostasis","K09667//protein O-GlcNAc transferase [EC:2.4.1.255]","NP_001307251.1//transmembrane and TPR repeat-containing protein 2 isoform 3 precursor [Homo sapiens];XP_012604984.1//transmembrane and TPR repeat-containing protein 2 isoform X3 [Microcebus murinus];NP_689801.1//transmembrane and TPR repeat-containing protein 2 isoform 1 precursor [Homo sapiens]","1//3;2//1"]
[51569,2687,14.57,10.38,-0.489194433706632,{"v":8.00183075246224e-06,"d":"8.00E-06"},"*",{"v":1.525828E-6,"d":"1.53E-06"},"UFM1","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005737//cytoplasm","NA","GO:1990592//protein K69-linked ufmylation;GO:0034976//response to endoplasmic reticulum stress;GO:0033146//regulation of intracellular estrogen receptor signaling pathway;GO:0071569//protein ufmylation;GO:0043066//negative regulation of apoptotic process","K12162//ubiquitin-fold modifier 1","NP_001273633.1//ubiquitin-fold modifier 1 isoform 3 [Homo sapiens];AAK55530.1//PRO3033 [Homo sapiens]","1//3;3//A2MP1"]
[23595,2586,13.65,9.73,-0.488389241026103,{"v":2.92837361783061e-05,"d":"2.93E-05"},"*",{"v":6.16876e-06,"d":"6.17E-06"},"ORC3","GO:0031261//DNA replication preinitiation complex;GO:0000808//origin recognition complex;GO:0005654//nucleoplasm;GO:0000784//nuclear chromosome, telomeric region;GO:0005656//nuclear pre-replicative complex;GO:0005664//nuclear origin of replication recognition complex;GO:0016604//nuclear body","GO:0003688//DNA replication origin binding","GO:0006267//pre-replicative complex assembly involved in nuclear cell cycle DNA replication;GO:0061351//neural precursor cell proliferation;GO:0006260//DNA replication;GO:0000082//G1/S transition of mitotic cell cycle;GO:0006270//DNA replication initiation","K02605//origin recognition complex subunit 3","NP_862820.1//origin recognition complex subunit 3 isoform 1 [Homo sapiens];XP_016866125.1//PREDICTED: origin recognition complex subunit 3 isoform X8 [Homo sapiens];NP_036513.2//origin recognition complex subunit 3 isoform 2 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[79794,5254,11.87,8.47,-0.486886060309708,{"v":5.481581e-09,"d":"5.48E-09"},"*",{"v":6.71214e-10,"d":"6.71E-10"},"C12orf49","GO:0005576//extracellular region","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K04487//cysteine desulfurase [EC:2.8.1.7]","BAC04924.1//unnamed protein product [Homo sapiens];NP_079014.1//UPF0454 protein C12orf49 isoform 1 precursor [Homo sapiens];NP_001340552.1//UPF0454 protein C12orf49 isoform 2 [Homo sapiens];NP_001340553.1//UPF0454 protein C12orf49 isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[10447,2538,12.43,8.87,-0.486820286751421,{"v":8.95637809915092e-05,"d":"8.96E-05"},"*",{"v":2.04706E-5,"d":"2.05E-05"},"FAM3C","GO:0070062//extracellular exosome;GO:0031089//platelet dense granule lumen;GO:0005576//extracellular region","GO:0005125//cytokine activity","GO:0002576//platelet degranulation;GO:0007275//multicellular organism development","K07747//beta-site APP-cleaving enzyme 2 (memapsin 1) [EC:3.4.23.45];K09666//beta-1,2-N-acetylglucosaminyltransferase [EC:2.4.1.-]","NP_055703.1//protein FAM3C precursor [Homo sapiens]","1//3;2//1"]
[100288142,18450,0.42,0.3,-0.485426827170242,0.0838598660416379,"*",0.0380766,"NBPF20","NA","NA","NA","K22244//regenerating islet-derived protein 4","NP_001265196.1//neuroblastoma breakpoint family member 20 [Homo sapiens]","1//3"]
[56853,4181,0.07,0.05,-0.485426827170242,0.782262985507246,"*",0.689316,"CELF4","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0000900//translation repressor activity, nucleic acid binding;GO:0036002//pre-mRNA binding;GO:0003729//mRNA binding;GO:0042835//BRE binding","GO:0006397//mRNA processing;GO:0006376//mRNA splice site selection;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0048026//positive regulation of mRNA splicing, via spliceosome;GO:0007281//germ cell development;GO:0090394//negative regulation of excitatory postsynaptic potential;GO:1902866//regulation of retina development in camera-type eye;GO:0009790//embryo development;GO:0008380//RNA splicing;GO:0048025//negative regulation of mRNA splicing, via spliceosome","K13207//CUG-BP- and ETR3-like factor;K12822//RNA-binding protein 25","XP_010817008.1//PREDICTED: CUGBP Elav-like family member 4 isoform X21 [Bos taurus];XP_022351209.1//CUGBP Elav-like family member 4 isoform X8 [Enhydra lutris kenyoni];XP_022351210.1//CUGBP Elav-like family member 4 isoform X9 [Enhydra lutris kenyoni];XP_020331806.1//octapeptide-repeat protein T2-like, partial [Oncorhynchus kisutch];NP_001340671.1//CUGBP Elav-like family member 4 isoform 18 [Homo sapiens];NP_001340636.1//CUGBP Elav-like family member 4 isoform 21 [Homo sapiens];NP_001340677.1//CUGBP Elav-like family member 4 isoform 33 [Homo sapiens];NP_001340646.1//CUGBP Elav-like family member 4 isoform 20 [Homo sapiens];XP_022351212.1//CUGBP Elav-like family member 4 isoform X11 [Enhydra lutris kenyoni];XP_022351205.1//CUGBP Elav-like family member 4 isoform X5 [Enhydra lutris kenyoni];BAD93011.1//bruno-like 4, RNA binding protein variant, partial [Homo sapiens];NP_001340626.1//CUGBP Elav-like family member 4 isoform 55 [Homo sapiens];XP_022351204.1//CUGBP Elav-like family member 4 isoform X4 [Enhydra lutris kenyoni];XP_022351206.1//CUGBP Elav-like family member 4 isoform X6 [Enhydra lutris kenyoni];XP_022351213.1//CUGBP Elav-like family member 4 isoform X12 [Enhydra lutris kenyoni];XP_022351202.1//CUGBP Elav-like family member 4 isoform X2 [Enhydra lutris kenyoni];XP_022351211.1//CUGBP Elav-like family member 4 isoform X10 [Enhydra lutris kenyoni];XP_022351208.1//CUGBP Elav-like family member 4 isoform X7 [Enhydra lutris kenyoni];XP_022351215.1//CUGBP Elav-like family member 4 isoform X14 [Enhydra lutris kenyoni];XP_021092374.1//CUGBP Elav-like family member 4 isoform X15 [Heterocephalus glaber];XP_022351203.1//CUGBP Elav-like family member 4 isoform X3 [Enhydra lutris kenyoni];XP_010817007.1//PREDICTED: CUGBP Elav-like family member 4 isoform X20 [Bos taurus];XP_022351221.1//CUGBP Elav-like family member 4 isoform X19 [Enhydra lutris kenyoni];XP_013365777.1//PREDICTED: CUGBP Elav-like family member 4 isoform X3 [Chinchilla lanigera]","1//3;3//A2MP1"]
[64844,3489,17.38,12.42,-0.484762908593919,{"v":3.01991964575646E-9,"d":"3.02E-09"},"*",{"v":3.58632E-10,"d":"3.59E-10"},"2019-03-07","NA","GO:0008270//zinc ion binding;GO:0016740//transferase activity","GO:0042130//negative regulation of T cell proliferation;GO:0016567//protein ubiquitination;GO:0002643//regulation of tolerance induction","K10662//E3 ubiquitin-protein ligase MARCH7 [EC:2.3.2.27]","NP_001269736.1//E3 ubiquitin-protein ligase MARCH7 isoform c [Homo sapiens];NP_073737.1//E3 ubiquitin-protein ligase MARCH7 isoform a [Homo sapiens];XP_008997084.1//PREDICTED: E3 ubiquitin-protein ligase MARCH7 isoform X4 [Callithrix jacchus]","1//3;3//A2MP1"]
[338376,1501,1.51,1.08,-0.48351723716161,0.39590808839779,"*",0.255702,"IFNE","GO:0005615//extracellular space","GO:0005132//type I interferon receptor binding;GO:0005125//cytokine activity;GO:0005126//cytokine receptor binding","GO:0051607//defense response to virus;GO:0043330//response to exogenous dsRNA;GO:0042742//defense response to bacterium;GO:0002250//adaptive immune response;GO:0042100//B cell proliferation;GO:0006959//humoral immune response;GO:0002286//T cell activation involved in immune response;GO:0002323//natural killer cell activation involved in immune response;GO:0033141//positive regulation of peptidyl-serine phosphorylation of STAT protein;GO:0030183//B cell differentiation;GO:0019221//cytokine-mediated signaling pathway;GO:0045087//innate immune response","K05442//interferon epsilon","NP_795372.1//interferon epsilon precursor [Homo sapiens]",4]
[6695,4841,6.85,4.9,-0.483322238845318,{"v":4.5505972583883e-05,"d":"4.55E-05"},"*",{"v":9.9336e-06,"d":"9.93E-06"},"SPOCK1","GO:0005615//extracellular space;GO:0016528//sarcoplasm;GO:0031594//neuromuscular junction;GO:0033268//node of Ranvier;GO:0014069//postsynaptic density;GO:0005737//cytoplasm;GO:0005578//proteinaceous extracellular matrix","GO:0004867//serine-type endopeptidase inhibitor activity;GO:0008191//metalloendopeptidase inhibitor activity;GO:0005509//calcium ion binding;GO:0004869//cysteine-type endopeptidase inhibitor activity","GO:0001558//regulation of cell growth;GO:0007399//nervous system development;GO:0007165//signal transduction;GO:0010951//negative regulation of endopeptidase activity;GO:0007155//cell adhesion;GO:0022008//neurogenesis;GO:0010977//negative regulation of neuron projection development;GO:0001764//neuron migration;GO:0010812//negative regulation of cell-substrate adhesion;GO:0021953//central nervous system neuron differentiation","K08136//sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican)","BAD92938.1//sparc/osteonectin, cwcv and kazal-like domains proteoglycan precursor variant, partial [Homo sapiens]","3//A2MP1"]
[2936,3189,137.41,98.35,-0.482490042357883,{"v":5.88496225157233e-64,"d":"5.88E-64"},"*",{"v":5.8577e-66,"d":"5.86E-66"},"GSR","GO:0005759//mitochondrial matrix;GO:0070062//extracellular exosome;GO:0009897//external side of plasma membrane;GO:0005829//cytosol;GO:0005739//mitochondrion","GO:0050661//NADP binding;GO:0009055//electron transfer activity;GO:0050660//flavin adenine dinucleotide binding;GO:0004362//glutathione-disulfide reductase activity","GO:0006749//glutathione metabolic process;GO:0034599//cellular response to oxidative stress;GO:0015949//nucleobase-containing small molecule interconversion;GO:0045454//cell redox homeostasis","K00383//glutathione reductase (NADPH) [EC:1.8.1.7]","NP_000628.2//glutathione reductase, mitochondrial isoform 1 precursor [Homo sapiens];NP_001182031.1//glutathione reductase, mitochondrial isoform 2 [Homo sapiens];NP_001182033.1//glutathione reductase, mitochondrial isoform 4 [Homo sapiens];NP_001182032.1//glutathione reductase, mitochondrial isoform 3 [Homo sapiens]","4;2//1"]
[57472,6347,5.43,3.89,-0.48118204281817,{"v":3.08510085553914e-05,"d":"3.09E-05"},"*",{"v":6.53754e-06,"d":"6.54E-06"},"CNOT6","GO:0016020//membrane;GO:0005634//nucleus;GO:0030014//CCR4-NOT complex;GO:0005829//cytosol","GO:0004535//poly(A)-specific ribonuclease activity;GO:0003723//RNA binding;GO:0046872//metal ion binding;GO:0004532//exoribonuclease activity","GO:2000327//positive regulation of ligand-dependent nuclear receptor transcription coactivator activity;GO:0070966//nuclear-transcribed mRNA catabolic process, no-go decay;GO:0043928//exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0010606//positive regulation of cytoplasmic mRNA processing body assembly;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0035195//gene silencing by miRNA;GO:0008284//positive regulation of cell proliferation","K12603//CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]","NP_001290170.1//CCR4-NOT transcription complex subunit 6 [Homo sapiens]","1//3"]
[57594,3741,5.89,4.22,-0.481024635123276,0.00109668022395023,"*",3.09012E-4,"HOMEZ","GO:0005730//nucleolus;GO:0005829//cytosol","GO:0003677//DNA binding","GO:0006355//regulation of transcription, DNA-templated","K15187//YEATS domain-containing protein 1/3;K19721//collagen, type V/XI/XXIV/XXVII, alpha","XP_020765451.1//homeobox and leucine zipper protein Homez isoform X2 [Odocoileus virginianus texanus]","2//1"]
[10247,1011,12.94,9.28,-0.479640906864935,0.0182377778587085,"*",0.00677152,"RIDA","GO:0005759//mitochondrial matrix;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005777//peroxisome;GO:0005737//cytoplasm","GO:1904013//xenon atom binding;GO:0003723//RNA binding;GO:0036041//long-chain fatty acid binding;GO:0019239//deaminase activity;GO:0046914//transition metal ion binding;GO:1904012//platinum binding;GO:0042803//protein homodimerization activity;GO:0016892//endoribonuclease activity, producing 3'-phosphomonoesters","GO:0030324//lung development;GO:0033993//response to lipid;GO:0001822//kidney development;GO:1901565//organonitrogen compound catabolic process;GO:0070314//G1 to G0 transition;GO:0007420//brain development;GO:0017148//negative regulation of translation;GO:1902074//response to salt;GO:0050680//negative regulation of epithelial cell proliferation","K09022//2-iminobutanoate/2-iminopropanoate deaminase [EC:3.5.99.10]","NP_005827.1//2-iminobutanoate/2-iminopropanoate deaminase [Homo sapiens]","2//1"]
[286207,1722,1.31,0.94,-0.478834149859813,0.395946466459868,"*",0.255702,"CFAP157","GO:0043231//intracellular membrane-bounded organelle;GO:0036064//ciliary basal body;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0008017//microtubule binding","GO:0007288//sperm axoneme assembly","K16628//collagen, type VII, alpha","EAW87684.1//chromosome 9 open reading frame 117, isoform CRA_b [Homo sapiens]","2//1"]
[222236,5271,2.87,2.06,-0.478406399492469,0.014419193631149,"*",0.00519304,"NAPEPLD","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0042622//photoreceptor outer segment membrane","GO:0042802//identical protein binding;GO:0008270//zinc ion binding;GO:0070290//N-acylphosphatidylethanolamine-specific phospholipase D activity;GO:0102200//N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity","GO:0035900//response to isolation stress;GO:0009395//phospholipid catabolic process;GO:0001523//retinoid metabolic process;GO:1903999//negative regulation of eating behavior;GO:0070291//N-acylethanolamine metabolic process;GO:0007568//aging","K13985//N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D [EC:3.1.4.54]","BAG65422.1//unnamed protein product [Homo sapiens]","4;1//3"]
[22908,3670,6.21,4.46,-0.477549558300177,0.00100928420370784,"*",0.00028287,"SACM1L","GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0032281//AMPA glutamate receptor complex;GO:0000139//Golgi membrane","GO:0043812//phosphatidylinositol-4-phosphate phosphatase activity;GO:0034596//phosphatidylinositol phosphate 4-phosphatase activity;GO:0042578//phosphoric ester hydrolase activity;GO:0004438//phosphatidylinositol-3-phosphatase activity;GO:0016791//phosphatase activity;GO:0034593//phosphatidylinositol bisphosphate phosphatase activity","GO:0006661//phosphatidylinositol biosynthetic process;GO:0046856//phosphatidylinositol dephosphorylation","K21797//phosphatidylinositol 4-phosphatase [EC:3.1.3.-]","NP_001306001.1//phosphatidylinositide phosphatase SAC1 isoform 2 [Homo sapiens];NP_054735.3//phosphatidylinositide phosphatase SAC1 isoform 1 [Homo sapiens]","1//3;4"]
[10786,1574,1.28,0.92,-0.476438043942987,0.44073377677734,"*",0.294172,"SLC17A3","GO:0005887//integral component of plasma membrane;GO:0016324//apical plasma membrane;GO:0031526//brush border membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm","GO:0015143//urate transmembrane transporter activity;GO:0019534//toxin transmembrane transporter activity;GO:0008308//voltage-gated anion channel activity;GO:0015562//efflux transmembrane transporter activity;GO:0008514//organic anion transmembrane transporter activity;GO:0015238//drug transmembrane transporter activity;GO:0005436//sodium:phosphate symporter activity","GO:0055085//transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0015711//organic anion transport;GO:0015747//urate transport;GO:0034220//ion transmembrane transport;GO:0015893//drug transport;GO:0006817//phosphate ion transport;GO:0015760//glucose-6-phosphate transport;GO:0006814//sodium ion transport;GO:0046415//urate metabolic process","K12300//MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 1/2/3/4","NP_001091956.1//sodium-dependent phosphate transport protein 4 isoform a [Homo sapiens];NP_006623.2//sodium-dependent phosphate transport protein 4 isoform b [Homo sapiens]","1//3;3//A2MP1"]
[10959,2127,140.99,101.38,-0.475819771158318,{"v":3.20457861276596e-37,"d":"3.20E-37"},"*",{"v":6.60014e-39,"d":"6.60E-39"},"TMED2","GO:0043231//intracellular membrane-bounded organelle;GO:0005783//endoplasmic reticulum;GO:0032580//Golgi cisterna membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0030137//COPI-coated vesicle;GO:0000139//Golgi membrane;GO:0042589//zymogen granule membrane;GO:0030133//transport vesicle;GO:0030663//COPI-coated vesicle membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0012507//ER to Golgi transport vesicle membrane","NA","GO:0032525//somite rostral/caudal axis specification;GO:0048208//COPII vesicle coating;GO:0035459//cargo loading into vesicle;GO:0036342//post-anal tail morphogenesis;GO:0001892//embryonic placenta development;GO:0006903//vesicle targeting;GO:0001756//somitogenesis;GO:0048205//COPI coating of Golgi vesicle;GO:0001893//maternal placenta development;GO:0006810//transport;GO:0060716//labyrinthine layer blood vessel development;GO:0072659//protein localization to plasma membrane;GO:0001701//in utero embryonic development;GO:0007030//Golgi organization;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0010628//positive regulation of gene expression;GO:0035264//multicellular organism growth;GO:0006886//intracellular protein transport;GO:0001947//heart looping;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0034260//negative regulation of GTPase activity;GO:0001843//neural tube closure;GO:0048598//embryonic morphogenesis","K20347//p24 family protein beta-1","XP_012637627.1//transmembrane emp24 domain-containing protein 2 isoform X2 [Microcebus murinus];XP_012637626.1//transmembrane emp24 domain-containing protein 2 isoform X1 [Microcebus murinus]","1//3;3//A2MP1"]
[199745,1611,8.09,5.82,-0.475120549521694,0.0170554884862932,"*",0.00627062,"THAP8","NA","GO:0046872//metal ion binding;GO:0003677//DNA binding","NA","K04632//guanine nucleotide-binding protein G(s) subunit alpha;K09228//KRAB domain-containing zinc finger protein;K22020//mucin-19;K04678//E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26];K04460//serine/threonine-protein phosphatase 5 [EC:3.1.3.16]","NP_001318031.1//THAP domain-containing protein 8 isoform b [Homo sapiens];NP_689871.1//THAP domain-containing protein 8 isoform a [Homo sapiens]","1//3;2//1"]
[23341,5946,3.21,2.31,-0.474680445706245,3.42388131782635E-3,"*",0.001068918,"DNAJC16","GO:0005623//cell;GO:0005829//cytosol;GO:0016021//integral component of membrane","NA","GO:0045454//cell redox homeostasis","K09536//DnaJ homolog subfamily C member 16","NP_056106.1//dnaJ homolog subfamily C member 16 isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[9364,1741,8.03,5.78,-0.474330495016635,0.0102747811764706,"*",3.56472E-3,"RAB28","NA","NA","NA","K07915//Ras-related protein Rab-28","XP_005554549.2//PREDICTED: ras-related protein Rab-28 isoform X2 [Macaca fascicularis];XP_014993487.1//PREDICTED: ras-related protein Rab-28 isoform X1 [Macaca mulatta]","1//3;3//A2MP1;2//1"]
[200942,1999,5.18,3.73,-0.473776467431316,0.0398018671193666,"*",0.01636526,"KLHDC8B","GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0031463//Cul3-RING ubiquitin ligase complex;GO:0030496//midbody","NA","GO:0051301//cell division;GO:0016567//protein ubiquitination;GO:0007049//cell cycle","K15046//influenza virus NS1A-binding protein;K10446//kelch-like protein 8","NP_775817.1//kelch domain-containing protein 8B [Homo sapiens]","2//1"]
[57187,5625,9.26,6.67,-0.473325432075651,{"v":3.44034838636364e-07,"d":"3.44E-07"},"*",{"v":5.30676e-08,"d":"5.31E-08"},"THOC2","GO:0000784//nuclear chromosome, telomeric region;GO:0005654//nucleoplasm;GO:0000347//THO complex;GO:0000445//THO complex part of transcription export complex;GO:0016607//nuclear speck;GO:0000346//transcription export complex","GO:0003729//mRNA binding","GO:0006406//mRNA export from nucleus;GO:0000902//cell morphogenesis;GO:0046784//viral mRNA export from host cell nucleus;GO:0006369//termination of RNA polymerase II transcription;GO:0031124//mRNA 3'-end processing;GO:0048699//generation of neurons;GO:0006405//RNA export from nucleus;GO:0048666//neuron development;GO:0010793//regulation of mRNA export from nucleus;GO:0016973//poly(A)+ mRNA export from nucleus;GO:0001824//blastocyst development;GO:0010977//negative regulation of neuron projection development;GO:0017145//stem cell division;GO:0008380//RNA splicing","K12879//THO complex subunit 2","NP_001075019.1//THO complex subunit 2 [Homo sapiens]","1//3"]
[79739,7837,0.68,0.49,-0.472752997135131,0.154776230308975,"*",0.0790256,"TTLL7","GO:0030425//dendrite;GO:0005929//cilium;GO:0005874//microtubule;GO:0005829//cytosol;GO:0043204//perikaryon","GO:0070740//tubulin-glutamic acid ligase activity;GO:0048487//beta-tubulin binding;GO:0005524//ATP binding;GO:0043014//alpha-tubulin binding","GO:0007399//nervous system development;GO:0018095//protein polyglutamylation;GO:0030154//cell differentiation","K16583//tubulin polyglutamylase TTLL7 [EC:6.-.-.-]","NP_078962.4//tubulin polyglutamylase TTLL7 isoform 1 [Homo sapiens]","1//3;5"]
[421,4056,0.43,0.31,-0.472068444315223,0.49334168956743,"*",0.339848,"ARVCF","GO:0005634//nucleus;GO:0005622//intracellular;GO:0005886//plasma membrane;GO:0005737//cytoplasm","NA","GO:0007155//cell adhesion;GO:0007275//multicellular organism development;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules","K05690//catenin (cadherin-associated protein), delta 1","NP_001661.1//armadillo repeat protein deleted in velo-cardio-facial syndrome [Homo sapiens]","2//1"]
[26286,2809,5.31,3.83,-0.471367468879196,0.010267237329002,"*",0.00356146,"ARFGAP3","GO:0016020//membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0000139//Golgi membrane","GO:0046872//metal ion binding;GO:0008565//protein transporter activity;GO:0005096//GTPase activator activity","GO:0006886//intracellular protein transport;GO:0009306//protein secretion;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0016192//vesicle-mediated transport","K12493//ADP-ribosylation factor GTPase-activating protein 2/3","NP_001135765.1//ADP-ribosylation factor GTPase-activating protein 3 isoform 2 [Homo sapiens];NP_055385.3//ADP-ribosylation factor GTPase-activating protein 3 isoform 1 [Homo sapiens]","4;1//3"]
[2125,6631,7.84,5.66,-0.470051601283326,{"v":2.56061247901235e-07,"d":"2.56E-07"},"*",{"v":3.89526e-08,"d":"3.90E-08"},"EVPL","GO:0005856//cytoskeleton;GO:0070062//extracellular exosome;GO:0045111//intermediate filament cytoskeleton;GO:0005829//cytosol;GO:0001533//cornified envelope;GO:0030057//desmosome","GO:0030674//protein binding, bridging;GO:0005198//structural molecule activity;GO:0019215//intermediate filament binding;GO:0045296//cadherin binding","GO:0018149//peptide cross-linking;GO:0008544//epidermis development;GO:0030216//keratinocyte differentiation;GO:0070268//cornification","K10383//envoplakin","NP_001979.2//envoplakin isoform 2 [Homo sapiens];NP_001307676.1//envoplakin isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[55293,2589,12.79,9.24,-0.469051507465579,{"v":1.72621619817851e-06,"d":"1.73E-06"},"*",{"v":2.96636e-07,"d":"2.97E-07"},"UEVLD","GO:0070062//extracellular exosome","GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor","GO:0019752//carboxylic acid metabolic process;GO:0006464//cellular protein modification process;GO:0005975//carbohydrate metabolic process;GO:0015031//protein transport","K00016//L-lactate dehydrogenase [EC:1.1.1.27];K01064//wingless-type MMTV integration site family, member 9;K12183//ESCRT-I complex subunit TSG101","XP_010349043.1//PREDICTED: ubiquitin-conjugating enzyme E2 variant 3 isoform X4 [Saimiri boliviensis boliviensis];NP_060784.3//ubiquitin-conjugating enzyme E2 variant 3 isoform b [Homo sapiens];NP_001248315.1//ubiquitin-conjugating enzyme E2 variant 3 isoform g [Homo sapiens];XP_008002998.1//PREDICTED: ubiquitin-conjugating enzyme E2 variant 3 isoform X10 [Chlorocebus sabaeus];NP_001248311.1//ubiquitin-conjugating enzyme E2 variant 3 isoform c [Homo sapiens];XP_008002941.1//PREDICTED: ubiquitin-conjugating enzyme E2 variant 3 isoform X3 [Chlorocebus sabaeus];XP_008002931.1//PREDICTED: ubiquitin-conjugating enzyme E2 variant 3 isoform X2 [Chlorocebus sabaeus];XP_008002973.1//PREDICTED: ubiquitin-conjugating enzyme E2 variant 3 isoform X7 [Chlorocebus sabaeus]","3//A2MP1;2//1;5"]
[678,3702,23.58,17.04,-0.468638382753924,{"v":3.17431780568407e-11,"d":"3.17E-11"},"*",{"v":3.0066e-12,"d":"3.01E-12"},"ZFP36L2","GO:0005634//nucleus;GO:0030529//intracellular ribonucleoprotein complex;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0017091//AU-rich element binding;GO:0035925//mRNA 3'-UTR AU-rich region binding;GO:0003700//DNA binding transcription factor activity","GO:0048103//somatic stem cell division;GO:0071385//cellular response to glucocorticoid stimulus;GO:0033077//T cell differentiation in thymus;GO:0035019//somatic stem cell population maintenance;GO:0071356//cellular response to tumor necrosis factor;GO:1900153//positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0070371//ERK1 and ERK2 cascade;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0008283//cell proliferation;GO:0060216//definitive hemopoiesis;GO:0043488//regulation of mRNA stability;GO:0030097//hemopoiesis;GO:0009611//response to wounding;GO:0045577//regulation of B cell differentiation;GO:1904628//cellular response to phorbol 13-acetate 12-myristate;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0045599//negative regulation of fat cell differentiation;GO:1901991//negative regulation of mitotic cell cycle phase transition;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0006402//mRNA catabolic process;GO:2000737//negative regulation of stem cell differentiation;GO:0061158//3'-UTR-mediated mRNA destabilization;GO:0097011//cellular response to granulocyte macrophage colony-stimulating factor stimulus","K18753//butyrate response factor","NP_008818.3//mRNA decay activator protein ZFP36L2 [Homo sapiens]",4]
[2035,5734,5.31,3.84,-0.467605550082997,0.000269727010351759,"*",{"v":6.72038e-05,"d":"6.72E-05"},"EPB41","GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0099738//cell cortex region;GO:0030054//cell junction;GO:0014069//postsynaptic density;GO:0030863//cortical cytoskeleton;GO:0014731//spectrin-associated cytoskeleton;GO:0043234//protein complex;GO:0005829//cytosol;GO:0009898//cytoplasmic side of plasma membrane;GO:0005886//plasma membrane","GO:0047485//protein N-terminus binding;GO:0005545//1-phosphatidylinositol binding;GO:0005200//structural constituent of cytoskeleton;GO:0003779//actin binding;GO:0008022//protein C-terminus binding;GO:0005198//structural molecule activity;GO:0005516//calmodulin binding;GO:0051219//phosphoprotein binding;GO:0030507//spectrin binding","GO:0006810//transport;GO:0031032//actomyosin structure organization;GO:0030036//actin cytoskeleton organization;GO:0030866//cortical actin cytoskeleton organization;GO:0008360//regulation of cell shape;GO:0032092//positive regulation of protein binding;GO:1904778//positive regulation of protein localization to cell cortex;GO:0051301//cell division;GO:0007049//cell cycle;GO:0006461//protein complex assembly","K06107//erythrocyte membrane protein band 4.1","XP_007977938.1//PREDICTED: protein 4.1 isoform X25 [Chlorocebus sabaeus];XP_009450495.1//PREDICTED: protein 4.1 isoform X21 [Pan troglodytes];XP_003271766.1//PREDICTED: protein 4.1 isoform X2 [Nomascus leucogenys];NP_001159477.1//protein 4.1 isoform 1 [Homo sapiens];NP_976218.1//protein 4.1 isoform 2 [Homo sapiens];BAD92886.1//Protein 4.1 variant, partial [Homo sapiens]","1//3;3//A2MP1;2//1"]
[256987,5178,4.13,2.99,-0.46599629722134,{"v":2.60383376100629e-05,"d":"2.60E-05"},"*",{"v":5.44272e-06,"d":"5.44E-06"},"SERINC5","GO:0070062//extracellular exosome;GO:0005794//Golgi apparatus;GO:0043209//myelin sheath;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0048471//perinuclear region of cytoplasm","GO:0015194//L-serine transmembrane transporter activity","GO:0042552//myelination;GO:0006658//phosphatidylserine metabolic process;GO:0009597//detection of virus;GO:0051607//defense response to virus;GO:0016032//viral process;GO:1904222//positive regulation of serine C-palmitoyltransferase activity;GO:0008654//phospholipid biosynthetic process;GO:1904219//positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity;GO:0006665//sphingolipid metabolic process;GO:0006564//L-serine biosynthetic process;GO:0045087//innate immune response","K16316//serine/threonine-protein kinase 31 [EC:2.7.11.1];K04175//C-X-C chemokine receptor type 1;K12025//tripartite motif-containing protein 52","NP_840060.1//serine incorporator 5 isoform 2 [Homo sapiens];NP_001167543.1//serine incorporator 5 isoform 1 [Homo sapiens];NP_001167542.1//serine incorporator 5 isoform 3 [Homo sapiens]","6;2//1"]
[116064,7683,11.24,8.14,-0.465541335954679,{"v":4.64469187540558e-11,"d":"4.64E-11"},"*",{"v":4.4807e-12,"d":"4.48E-12"},"LRRC58","NA","NA","NA","K17985//activating molecule in BECN1-regulated autophagy protein 1","AAH13757.1//LRRC58 protein, partial [Homo sapiens]","1//3"]
[201475,2138,16.65,12.07,-0.464096501203603,{"v":5.21890087105039e-05,"d":"5.22E-05"},"*",{"v":1.14774E-5,"d":"1.15E-05"},"RAB12","GO:0055038//recycling endosome membrane;GO:0005764//lysosome;GO:0005776//autophagosome","GO:0019003//GDP binding;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0016239//positive regulation of macroautophagy;GO:0044257//cellular protein catabolic process;GO:0008333//endosome to lysosome transport","K07907//Ras-related protein Rab-12","XP_007972827.1//PREDICTED: ras-related protein Rab-12 [Chlorocebus sabaeus]","2//1"]
[253260,9518,4.66,3.38,-0.463306708372096,{"v":3.68144616949153e-06,"d":"3.68E-06"},"*",{"v":6.66274E-7,"d":"6.66E-07"},"RICTOR","GO:0031932//TORC2 complex;GO:0005829//cytosol","GO:0043022//ribosome binding;GO:0008047//enzyme activator activity;GO:0019901//protein kinase binding","GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0042325//regulation of phosphorylation;GO:0010468//regulation of gene expression;GO:0051897//positive regulation of protein kinase B signaling;GO:0051896//regulation of protein kinase B signaling;GO:0031295//T cell costimulation;GO:0033135//regulation of peptidyl-serine phosphorylation;GO:0032956//regulation of actin cytoskeleton organization;GO:0032008//positive regulation of TOR signaling;GO:0030950//establishment or maintenance of actin cytoskeleton polarity;GO:0001938//positive regulation of endothelial cell proliferation;GO:0030838//positive regulation of actin filament polymerization;GO:0031929//TOR signaling;GO:0031532//actin cytoskeleton reorganization;GO:0050727//regulation of inflammatory response;GO:0038111//interleukin-7-mediated signaling pathway;GO:0030010//establishment of cell polarity;GO:2000114//regulation of establishment of cell polarity;GO:0043087//regulation of GTPase activity;GO:0018105//peptidyl-serine phosphorylation;GO:0009790//embryo development;GO:0048015//phosphatidylinositol-mediated signaling","K08267//rapamycin-insensitive companion of mTOR","NP_689969.2//rapamycin-insensitive companion of mTOR isoform 1 [Homo sapiens];XP_006714526.1//PREDICTED: rapamycin-insensitive companion of mTOR isoform X5 [Homo sapiens];NP_001272368.1//rapamycin-insensitive companion of mTOR isoform 2 [Homo sapiens]","4;1//3"]
[57179,2675,45.35,32.91,-0.462576524291536,{"v":7.93783050666667e-16,"d":"7.94E-16"},"*",{"v":5.21768e-17,"d":"5.22E-17"},"KIAA1191","GO:0005737//cytoplasm","GO:0016491//oxidoreductase activity","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K04613//vomeronasal 2 receptor;K01064//wingless-type MMTV integration site family, member 9","BAB14957.1//unnamed protein product [Homo sapiens];NP_065177.2//putative monooxygenase p33MONOX isoform a [Homo sapiens]","4;1//3;2//1"]
[84945,5316,2.41,1.75,-0.461678224397633,0.0234372785735318,"*",0.00896908,"ABHD13","NA","NA","NA","K06889//uncharacterized protein","XP_021785455.1//protein ABHD13 isoform X1 [Papio anubis]","2//1"]
[6309,6976,4.79,3.48,-0.460938349887452,{"v":7.15281505869263e-05,"d":"7.15E-05"},"*",{"v":1.609764e-05,"d":"1.61E-05"},"SC5D","GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0005506//iron ion binding;GO:0000248//C-5 sterol desaturase activity;GO:0050046//lathosterol oxidase activity;GO:0016491//oxidoreductase activity","GO:0033490//cholesterol biosynthetic process via lathosterol;GO:0033489//cholesterol biosynthetic process via desmosterol;GO:0008610//lipid biosynthetic process;GO:0045540//regulation of cholesterol biosynthetic process;GO:0006629//lipid metabolic process","K00227//Delta7-sterol 5-desaturase [EC:1.14.19.20]","NP_008849.2//lathosterol oxidase [Homo sapiens]","4;2//1"]
[81566,4603,6.48,4.71,-0.460266753271842,2.38861763410302E-4,"*",{"v":5.89304e-05,"d":"5.89E-05"},"CSRNP2","GO:0005634//nucleus","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0019902//phosphatase binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0010923//negative regulation of phosphatase activity;GO:0006915//apoptotic process","K17494//cysteine/serine-rich nuclear protein","NP_110436.1//cysteine/serine-rich nuclear protein 2 [Homo sapiens]","2//1"]
[128553,11671,0.22,0.16,-0.459431618637297,0.314920515957895,"*",0.1872884,"TSHZ2","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007275//multicellular organism development;GO:0006351//transcription, DNA-templated","K09236//teashirt","NP_001180350.1//teashirt homolog 2 isoform 2 [Homo sapiens];NP_775756.3//teashirt homolog 2 isoform 1 [Homo sapiens]","1//3;5"]
[117247,2918,0.11,0.08,-0.459431618637297,0.812279572086532,"*",0.728682,"SLC16A10","GO:0016323//basolateral plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0015349//thyroid hormone transmembrane transporter activity;GO:0008028//monocarboxylic acid transmembrane transporter activity;GO:0015173//aromatic amino acid transmembrane transporter activity;GO:0015171//amino acid transmembrane transporter activity","GO:0006865//amino acid transport;GO:0015801//aromatic amino acid transport","K08187//MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 10","NP_061063.2//monocarboxylate transporter 10 [Homo sapiens]",4]
[64965,1473,17.54,12.76,-0.459020418679864,0.000822802652114598,"*",2.26536E-4,"MRPS9","GO:0005840//ribosome;GO:0005730//nucleolus;GO:0005763//mitochondrial small ribosomal subunit;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome","GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006412//translation;GO:0070126//mitochondrial translational termination;GO:0042769//DNA damage response, detection of DNA damage;GO:0070125//mitochondrial translational elongation","K02996//small subunit ribosomal protein S9","NP_872578.1//28S ribosomal protein S9, mitochondrial [Homo sapiens]","2//1"]
[54870,3164,33.08,24.08,-0.458123842411573,{"v":5.88756e-13,"d":"5.89E-13"},"*",{"v":4.8246e-14,"d":"4.82E-14"},"QRICH1","GO:0005654//nucleoplasm;GO:0005737//cytoplasm","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0003677//DNA binding","GO:0007275//multicellular organism development;GO:0007010//cytoskeleton organization;GO:0022604//regulation of cell morphogenesis","K09187//histone-lysine N-methyltransferase MLL2 [EC:2.1.1.43];K17335//nuclear factor of activated T-cells 5","NP_060200.2//glutamine-rich protein 1 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[1786,5373,28.71,20.91,-0.457360268617602,{"v":1.57269602325581e-18,"d":"1.57E-18"},"*",{"v":8.467e-20,"d":"8.47E-20"},"DNMT1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005721//pericentric heterochromatin;GO:0005657//replication fork","GO:0003723//RNA binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0008270//zinc ion binding;GO:1990841//promoter-specific chromatin binding;GO:0003886//DNA (cytosine-5-)-methyltransferase activity;GO:0009008//DNA-methyltransferase activity;GO:0008327//methyl-CpG binding","GO:0051571//positive regulation of histone H3-K4 methylation;GO:0010216//maintenance of DNA methylation;GO:0016458//gene silencing;GO:0042127//regulation of cell proliferation;GO:0006351//transcription, DNA-templated;GO:0090309//positive regulation of methylation-dependent chromatin silencing;GO:0010628//positive regulation of gene expression;GO:0006306//DNA methylation;GO:0043045//DNA methylation involved in embryo development;GO:0071230//cellular response to amino acid stimulus;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0016569//covalent chromatin modification;GO:0045814//negative regulation of gene expression, epigenetic;GO:0051573//negative regulation of histone H3-K9 methylation;GO:0007265//Ras protein signal transduction","K00558//DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]","NP_001124295.1//DNA (cytosine-5)-methyltransferase 1 isoform a [Homo sapiens];XP_512361.4//PREDICTED: DNA (cytosine-5)-methyltransferase 1 isoform X2 [Pan troglodytes];XP_016790461.1//PREDICTED: DNA (cytosine-5)-methyltransferase 1 isoform X6 [Pan troglodytes];EAW84079.1//DNA (cytosine-5-)-methyltransferase 1, isoform CRA_a [Homo sapiens]","1//3;3//A2MP1;2//1"]
[5868,2533,18.24,13.29,-0.456764624888567,{"v":2.80510412108413e-06,"d":"2.81E-06"},"*",{"v":4.98892e-07,"d":"4.99E-07"},"RAB5A","GO:0010008//endosome membrane;GO:0030425//dendrite;GO:0042470//melanosome;GO:0005737//cytoplasm;GO:0043025//neuronal cell body;GO:0045335//phagocytic vesicle;GO:0097443//sorting endosome;GO:0098559//cytoplasmic side of early endosome membrane;GO:0005829//cytosol;GO:0030665//clathrin-coated vesicle membrane;GO:0015629//actin cytoskeleton;GO:0043679//axon terminus;GO:0005886//plasma membrane;GO:0005769//early endosome;GO:0070382//exocytic vesicle;GO:0070062//extracellular exosome;GO:0030424//axon;GO:0036477//somatodendritic compartment;GO:0008021//synaptic vesicle;GO:0030670//phagocytic vesicle membrane;GO:0043195//terminal bouton;GO:0005768//endosome;GO:0001726//ruffle;GO:0031901//early endosome membrane;GO:0030139//endocytic vesicle;GO:0045121//membrane raft;GO:0005811//lipid droplet","GO:0019003//GDP binding;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0043687//post-translational protein modification;GO:0036465//synaptic vesicle recycling;GO:0045022//early endosome to late endosome transport;GO:0007596//blood coagulation;GO:0030100//regulation of endocytosis;GO:0006661//phosphatidylinositol biosynthetic process;GO:0045921//positive regulation of exocytosis;GO:2000286//receptor internalization involved in canonical Wnt signaling pathway;GO:0006897//endocytosis;GO:0015031//protein transport;GO:0051489//regulation of filopodium assembly;GO:0006909//phagocytosis;GO:2000785//regulation of autophagosome assembly;GO:2000300//regulation of synaptic vesicle exocytosis;GO:0051036//regulation of endosome size;GO:0061024//membrane organization;GO:0039694//viral RNA genome replication;GO:0045056//transcytosis","K07887//Ras-related protein Rab-5A","NP_001278977.1//ras-related protein Rab-5A isoform 2 [Homo sapiens];NP_004153.2//ras-related protein Rab-5A isoform 1 [Homo sapiens]","1//3;4"]
[55208,3046,5.31,3.87,-0.456378294659743,0.0101446876892502,"*",0.00351514,"DCUN1D2","GO:0000151//ubiquitin ligase complex","GO:0032182//ubiquitin-like protein binding;GO:0097602//cullin family protein binding;GO:0031624//ubiquitin conjugating enzyme binding","GO:0045116//protein neddylation;GO:0051443//positive regulation of ubiquitin-protein transferase activity","K17822//DCN1-like protein 1/2","NP_001014305.1//DCN1-like protein 2 [Homo sapiens]","1//3"]
[9725,4469,3.47,2.53,-0.455798277883951,0.0119424990526876,"*",0.00421434,"TMEM63A","GO:0005765//lysosomal membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0005815//microtubule organizing center;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane;GO:0005886//plasma membrane;GO:0070821//tertiary granule membrane","GO:0003676//nucleic acid binding","GO:0043312//neutrophil degranulation;GO:0006811//ion transport","K21989//calcium permeable stress-gated cation channel","BAD96654.1//Hypothetical protein KIAA0792 (Novel protein) variant, partial [Homo sapiens]","2//1"]
[26056,4362,19.19,14,-0.454927884363051,{"v":2.61967877970149e-10,"d":"2.62E-10"},"*",{"v":2.74694e-11,"d":"2.75E-11"},"RAB11FIP5","GO:0030658//transport vesicle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005815//microtubule organizing center;GO:0005741//mitochondrial outer membrane;GO:0000139//Golgi membrane;GO:0030141//secretory granule;GO:0055038//recycling endosome membrane;GO:0031901//early endosome membrane;GO:0005794//Golgi apparatus;GO:0005769//early endosome;GO:0055037//recycling endosome","GO:0043015//gamma-tubulin binding;GO:0017137//Rab GTPase binding","GO:2000008//regulation of protein localization to cell surface;GO:0035773//insulin secretion involved in cellular response to glucose stimulus;GO:0045055//regulated exocytosis;GO:0070164//negative regulation of adiponectin secretion;GO:0071468//cellular response to acidic pH","K12484//Rab11 family-interacting protein 1/2/5","NP_056285.1//rab11 family-interacting protein 5 [Homo sapiens]","2//1"]
[10845,4788,13.35,9.75,-0.453365617937943,{"v":5.38825676122083E-8,"d":"5.39E-08"},"*",{"v":7.51536e-09,"d":"7.52E-09"},"CLPX","GO:0005759//mitochondrial matrix;GO:0005654//nucleoplasm;GO:0042645//mitochondrial nucleoid;GO:0009841//mitochondrial endopeptidase Clp complex;GO:0005829//cytosol;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0009368//endopeptidase Clp complex","GO:0016504//peptidase activator activity;GO:0046872//metal ion binding;GO:0005524//ATP binding;GO:0051082//unfolded protein binding;GO:0004176//ATP-dependent peptidase activity;GO:0016887//ATPase activity","GO:0006457//protein folding;GO:0046034//ATP metabolic process;GO:0006508//proteolysis;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0030163//protein catabolic process","K03544//ATP-dependent Clp protease ATP-binding subunit ClpX","NP_006651.2//ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial precursor [Homo sapiens]",4]
[23251,6742,0.26,0.19,-0.452512204697507,0.493386526583659,"*",0.339848,"KIAA1024","GO:0016021//integral component of membrane","NA","NA","K08631//a disintegrin and metalloproteinase with thrombospondin motifs 17 [EC:3.4.24.-]","NP_056021.1//UPF0258 protein KIAA1024 [Homo sapiens]","2//1"]
[60592,1882,14.64,10.7,-0.452304756995533,0.000629056716044776,"*",0.0001688616,"SCOC","GO:0005768//endosome;GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005802//trans-Golgi network;GO:0000139//Golgi membrane","NA","GO:0016239//positive regulation of macroautophagy;GO:0061635//regulation of protein complex stability","K20316//short coiled-coil protein","NP_001147135.1//short coiled-coil protein isoform 2 [Homo sapiens];NP_001147024.1//short coiled-coil protein isoform 3 [Homo sapiens];NP_001147107.1//short coiled-coil protein isoform 5 [Homo sapiens];NP_115936.2//short coiled-coil protein isoform 4 [Homo sapiens];NP_001146956.1//short coiled-coil protein isoform 1 [Homo sapiens];NP_001147162.1//short coiled-coil protein isoform 6 [Homo sapiens]","1//3;2//1"]
[144608,1139,1.08,0.79,-0.451106753986366,0.602420930011862,"*",0.445084,"C12orf60","NA","NA","NA","NA","XP_003265586.2//PREDICTED: uncharacterized protein C12orf60 homolog [Nomascus leucogenys]","3//A2MP1"]
[1185,5647,4.85,3.55,-0.450165722682445,0.000601593559344262,"*",1.608116E-4,"CLCN6","GO:0005765//lysosomal membrane;GO:0010008//endosome membrane;GO:0016021//integral component of membrane","GO:0005524//ATP binding;GO:0005247//voltage-gated chloride channel activity;GO:0015297//antiporter activity","GO:0009612//response to mechanical stimulus;GO:0006884//cell volume homeostasis;GO:0007165//signal transduction;GO:0006821//chloride transport;GO:0034220//ion transmembrane transport;GO:1902476//chloride transmembrane transport","K05015//chloride channel 6","NP_001243888.1//chloride transport protein 6 isoform 2 [Homo sapiens];NP_001277.1//chloride transport protein 6 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[55676,4969,13.61,9.97,-0.449001657105799,{"v":1.75042132188841e-08,"d":"1.75E-08"},"*",{"v":2.29788e-09,"d":"2.30E-09"},"SLC30A6","GO:0016020//membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0008324//cation transmembrane transporter activity;GO:0005385//zinc ion transmembrane transporter activity","GO:0010043//response to zinc ion;GO:0061088//regulation of sequestering of zinc ion","K14693//solute carrier family 30 (zinc transporter), member 6","NP_001180442.1//zinc transporter 6 isoform 1 [Homo sapiens];XP_016803799.1//PREDICTED: zinc transporter 6 isoform X9 [Pan troglodytes];NP_001180443.1//zinc transporter 6 isoform 3 [Homo sapiens];NP_001180444.1//zinc transporter 6 isoform 4 [Homo sapiens];NP_060434.2//zinc transporter 6 isoform 2 [Homo sapiens]","4;1//3;2//1"]
[55023,11987,2.17,1.59,-0.448668277160124,0.000791225759195796,"*",0.000216802,"PHIP","GO:0070062//extracellular exosome;GO:0005634//nucleus","GO:0070577//lysine-acetylated histone binding;GO:0005158//insulin receptor binding","GO:0008286//insulin receptor signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0008360//regulation of cell shape;GO:0045893//positive regulation of transcription, DNA-templated;GO:0043568//positive regulation of insulin-like growth factor receptor signaling pathway;GO:0001932//regulation of protein phosphorylation;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007010//cytoskeleton organization;GO:0022604//regulation of cell morphogenesis;GO:0045840//positive regulation of mitotic nuclear division;GO:0008284//positive regulation of cell proliferation","K11797//PH-interacting protein","NP_060404.4//PH-interacting protein [Homo sapiens]",6]
[65267,11356,0.15,0.11,-0.447458976971221,0.478575887096774,"*",0.32692,"WNK3","GO:0005829//cytosol;GO:0005923//bicellular tight junction;GO:0005737//cytoplasm;GO:0005912//adherens junction","GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0019869//chloride channel inhibitor activity","GO:2000021//regulation of ion homeostasis;GO:0035556//intracellular signal transduction;GO:0090279//regulation of calcium ion import;GO:1903078//positive regulation of protein localization to plasma membrane;GO:0072659//protein localization to plasma membrane;GO:0006468//protein phosphorylation;GO:0043066//negative regulation of apoptotic process;GO:2000651//positive regulation of sodium ion transmembrane transporter activity;GO:0010765//positive regulation of sodium ion transport;GO:0046777//protein autophosphorylation;GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:0032414//positive regulation of ion transmembrane transporter activity;GO:2000682//positive regulation of rubidium ion transport;GO:0090188//negative regulation of pancreatic juice secretion;GO:2000688//positive regulation of rubidium ion transmembrane transporter activity;GO:0051928//positive regulation of calcium ion transport","K08867//WNK lysine deficient protein kinase [EC:2.7.11.1]","NP_065973.2//serine/threonine-protein kinase WNK3 isoform 1 [Homo sapiens];NP_001002838.1//serine/threonine-protein kinase WNK3 isoform 2 [Homo sapiens]","4;3//A2MP1"]
[22916,2249,15.16,11.12,-0.447112965447584,{"v":3.15719973388284e-05,"d":"3.16E-05"},"*",{"v":6.71404e-06,"d":"6.71E-06"},"NCBP2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005845//mRNA cap binding complex;GO:0034518//RNA cap binding complex;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005846//nuclear cap binding complex","GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0000339//RNA cap binding;GO:0000340//RNA 7-methylguanosine cap binding;GO:0017069//snRNA binding","GO:0006406//mRNA export from nucleus;GO:0008334//histone mRNA metabolic process;GO:0042795//snRNA transcription from RNA polymerase II promoter;GO:0006408//snRNA export from nucleus;GO:0006370//7-methylguanosine mRNA capping;GO:0006369//termination of RNA polymerase II transcription;GO:0045292//mRNA cis splicing, via spliceosome;GO:0031124//mRNA 3'-end processing;GO:0006405//RNA export from nucleus;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0098789//pre-mRNA cleavage required for polyadenylation;GO:0051168//nuclear export;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0016070//RNA metabolic process;GO:0000398//mRNA splicing, via spliceosome;GO:0046833//positive regulation of RNA export from nucleus;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0031047//gene silencing by RNA;GO:0006366//transcription from RNA polymerase II promoter;GO:0006446//regulation of translational initiation;GO:0031442//positive regulation of mRNA 3'-end processing;GO:0008380//RNA splicing","K12883//nuclear cap-binding protein subunit 2","NP_001036005.1//nuclear cap-binding protein subunit 2 isoform 2 [Homo sapiens];XP_008007826.1//PREDICTED: nuclear cap-binding protein subunit 2 isoform X2 [Chlorocebus sabaeus];NP_001294965.1//nuclear cap-binding protein subunit 2 isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[55691,5972,1.09,0.8,-0.446256229889564,0.256552280968097,"*",0.145991,"FRMD4A","GO:0005856//cytoskeleton;GO:0005923//bicellular tight junction;GO:0005737//cytoplasm;GO:0005912//adherens junction","GO:0030674//protein binding, bridging","GO:0090162//establishment of epithelial cell polarity","K10955//mucin-2;K12817//pre-mRNA-splicing factor 18;K05762//radixin;K16684//merlin;K21125//mucin-5AC;K05763//moesin","XP_015311068.1//PREDICTED: FERM domain-containing protein 4A isoform X11 [Macaca fascicularis];XP_008000516.1//PREDICTED: FERM domain-containing protein 4A isoform X3 [Chlorocebus sabaeus];XP_005252546.1//PREDICTED: FERM domain-containing protein 4A isoform X9 [Homo sapiens];XP_016871883.1//PREDICTED: FERM domain-containing protein 4A isoform X12 [Homo sapiens]","4;1//3"]
[54882,7501,6.64,4.88,-0.444302093784038,{"v":6.89336496247582e-07,"d":"6.89E-07"},"*",{"v":1.115522E-7,"d":"1.12E-07"},"ANKHD1","NA","NA","NA","K16726//ankyrin repeat domain-containing protein 17","NP_060217.1//ankyrin repeat and KH domain-containing protein 1 isoform 1 [Homo sapiens];EHH54586.1//hypothetical protein EGM_15457 [Macaca fascicularis]","1//3;3//A2MP1;2//1"]
[55055,3181,20.26,14.89,-0.444290420219038,{"v":5.91612266012489e-08,"d":"5.92E-08"},"*",{"v":8.30346e-09,"d":"8.30E-09"},"ZWILCH","GO:1990423//RZZ complex;GO:0005829//cytosol;GO:0000776//kinetochore;GO:0000777//condensed chromosome kinetochore","NA","GO:0007093//mitotic cell cycle checkpoint;GO:0007062//sister chromatid cohesion;GO:0051301//cell division","K11579//protein zwilch","NP_060445.3//protein zwilch homolog isoform 1 [Homo sapiens];XP_009248219.1//PREDICTED: protein zwilch homolog isoform X2 [Pongo abelii]","4;1//3"]
[23099,5903,2.42,1.78,-0.443129806308197,0.0213957495349992,"*",0.00809406,"ZBTB43","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K10514//zinc finger and BTB domain-containing protein 43","XP_012627394.1//zinc finger and BTB domain-containing protein 43 isoform X1 [Microcebus murinus];ELK07206.1//Zinc finger and BTB domain-containing protein 43 [Pteropus alecto]","1//3;3//A2MP1"]
[2618,3012,30.74,22.62,-0.442518235700951,{"v":1.4559162815546e-10,"d":"1.46E-10"},"*",{"v":1.477426e-11,"d":"1.48E-11"},"GART","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0005524//ATP binding;GO:0004641//phosphoribosylformylglycinamidine cyclo-ligase activity;GO:0004637//phosphoribosylamine-glycine ligase activity;GO:0004644//phosphoribosylglycinamide formyltransferase activity","GO:0021549//cerebellum development;GO:0009113//purine nucleobase biosynthetic process;GO:0006189//'de novo' IMP biosynthetic process;GO:0021987//cerebral cortex development;GO:0046654//tetrahydrofolate biosynthetic process;GO:0010035//response to inorganic substance;GO:0010033//response to organic substance;GO:0006544//glycine metabolic process;GO:0003360//brainstem development;GO:0009168//purine ribonucleoside monophosphate biosynthetic process","K11787//phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.4.13 2.1.2.2 6.3.3.1]","XP_003927696.1//PREDICTED: trifunctional purine biosynthetic protein adenosine-3 isoform X1 [Saimiri boliviensis boliviensis];BAD92022.1//phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase isoform 1 variant, partial [Homo sapiens]","4;1//3;2//1"]
[1629,10831,1.78,1.31,-0.442310429428947,0.0052994107134864,"*",0.001719472,"DBT","GO:0042645//mitochondrial nucleoid","GO:0016746//transferase activity, transferring acyl groups;GO:0031625//ubiquitin protein ligase binding","GO:0008152//metabolic process","K09699//2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase) [EC:2.3.1.168]","AAA35589.1//branched chain acyltransferase precursor [Homo sapiens]","3//A2MP1"]
[9373,4908,11.05,8.14,-0.440945670012547,{"v":1.12668912364587E-6,"d":"1.13E-06"},"*",{"v":1.88816e-07,"d":"1.89E-07"},"PLAA","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0043130//ubiquitin binding;GO:0016005//phospholipase A2 activator activity","GO:0007165//signal transduction;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0006644//phospholipid metabolic process;GO:0010992//ubiquitin recycling;GO:0016236//macroautophagy;GO:0006954//inflammatory response","K14018//phospholipase A-2-activating protein","NP_001308475.1//phospholipase A-2-activating protein isoform 2 [Homo sapiens];XP_002819776.1//PREDICTED: phospholipase A-2-activating protein [Pongo abelii]","1//3;2//1"]
[9883,6087,38.04,28.04,-0.44003089684994,{"v":1.5934896017341E-21,"d":"1.59E-21"},"*",{"v":6.90306e-23,"d":"6.90E-23"},"POM121","NA","NA","NA","K14316//nuclear pore complex protein Nup121","XP_009441437.2//PREDICTED: nuclear envelope pore membrane protein POM 121C isoform X1 [Pan troglodytes]","4;2//1"]
[11179,2687,3.12,2.3,-0.439912167917873,0.0995219390803057,"*",0.0464714,"ZNF277","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:2000772//regulation of cellular senescence;GO:0070301//cellular response to hydrogen peroxide","K06245//laminin, beta 4;K12581//CCR4-NOT transcription complex subunit 7/8;K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K07575//PUA domain protein","XP_017734154.1//PREDICTED: zinc finger protein 277 isoform X1 [Rhinopithecus bieti]","2//1"]
[3161,2959,15.16,11.19,-0.438059717194698,{"v":7.47034917491749e-06,"d":"7.47E-06"},"*",{"v":1.417e-06,"d":"1.42E-06"},"HMMR","GO:0016020//membrane;GO:0009986//cell surface;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0005540//hyaluronic acid binding","GO:0010389//regulation of G2/M transition of mitotic cell cycle;GO:0030214//hyaluronan catabolic process","K06267//hyaluronan-mediated motility receptor","XP_003810951.1//PREDICTED: hyaluronan mediated motility receptor isoform X1 [Pan paniscus];XP_008961538.1//PREDICTED: hyaluronan mediated motility receptor isoform X2 [Pan paniscus];NP_001136029.1//hyaluronan mediated motility receptor isoform d [Homo sapiens]","1//3;2//1"]
[55922,3277,7.65,5.65,-0.437208880277464,1.44439756910393E-3,"*",0.000416754,"NKRF","GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005730//nucleolus","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003723//RNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0007165//signal transduction;GO:0045944//positive regulation of transcription from RNA polymerase II promoter","K13096//splicing factor 4;K13094//RNA-binding protein 5/10;K13166//splicing factor, arginine/serine-rich 14","NP_001166958.1//NF-kappa-B-repressing factor isoform 1 [Homo sapiens];XP_008017613.1//PREDICTED: NF-kappa-B-repressing factor [Chlorocebus sabaeus]","1//3;3//A2MP1"]
[29083,1364,6.85,5.06,-0.436966603153579,0.0783425931840312,"*",0.0352576,"GTPBP8","GO:0005739//mitochondrion","GO:0046872//metal ion binding;GO:0005525//GTP binding","NA","NA","NP_054889.2//GTP-binding protein 8 isoform 1 [Homo sapiens];NP_612494.1//GTP-binding protein 8 isoform 2 [Homo sapiens]","1//3;2//1"]
[51534,3371,14.57,10.77,-0.435982627520305,{"v":5.53551631946309e-06,"d":"5.54E-06"},"*",{"v":1.032668E-6,"d":"1.03E-06"},"VTA1","GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0010008//endosome membrane;GO:0005654//nucleoplasm;GO:0005829//cytosol","GO:0008022//protein C-terminus binding","GO:0016197//endosomal transport;GO:0046755//viral budding;GO:0071985//multivesicular body sorting pathway;GO:0019058//viral life cycle;GO:1904903//ESCRT III complex disassembly;GO:0036258//multivesicular body assembly;GO:0015031//protein transport;GO:0016236//macroautophagy","K12199//vacuolar protein sorting-associated protein VTA1","NP_001273300.1//vacuolar protein sorting-associated protein VTA1 homolog isoform b [Homo sapiens];NP_057569.2//vacuolar protein sorting-associated protein VTA1 homolog isoform a [Homo sapiens];NP_001273301.1//vacuolar protein sorting-associated protein VTA1 homolog isoform c [Homo sapiens]","4;1//3"]
[3305,2550,0.73,0.54,-0.434937056716549,0.506344737846597,"*",0.352102,"HSPA1L","NA","NA","NA","K03283//heat shock 70kDa protein 1/2/6/8","EAX03527.1//heat shock 70kDa protein 1-like [Homo sapiens]","3//A2MP1"]
[339263,7912,4.46,3.3,-0.434577685674489,1.29348680297398E-4,"*",{"v":3.0495e-05,"d":"3.05E-05"},"C17orf51","NA","NA","NA","K08798//MAP/microtubule affinity-regulating kinase [EC:2.7.11.1]","NP_001106905.1//uncharacterized protein C17orf51 [Homo sapiens]",4]
[205428,3604,3.77,2.79,-0.434299401439477,0.00805651648148148,"*",0.0027235,"C3orf58","GO:0005615//extracellular space;GO:0030126//COPI vesicle coat;GO:0000139//Golgi membrane","NA","GO:0060038//cardiac muscle cell proliferation;GO:0014066//regulation of phosphatidylinositol 3-kinase signaling","K17046//protein DEK;K16628//collagen, type VII, alpha;K02599//Notch 1","NP_775823.1//deleted in autism protein 1 isoform a precursor [Homo sapiens];NP_001127942.1//deleted in autism protein 1 isoform b [Homo sapiens]","1//3;3//A2MP1"]
[196294,777,9.55,7.07,-0.433790518113712,0.112170133105623,"*",0.0534518,"IMMP1L","NA","NA","NA","K09647//mitochondrial inner membrane protease subunit 1 [EC:3.4.21.-]","XP_008954127.1//PREDICTED: mitochondrial inner membrane protease subunit 1 isoform X2 [Pan paniscus];XP_008954126.1//PREDICTED: mitochondrial inner membrane protease subunit 1 isoform X1 [Pan paniscus]","1//3;2//1"]
[3775,2161,5.71,4.23,-0.432833082242893,0.0374120165903151,"*",0.01523508,"KCNK1","GO:0043231//intracellular membrane-bounded organelle;GO:0030425//dendrite;GO:0016324//apical plasma membrane;GO:1902937//inward rectifier potassium channel complex;GO:0031526//brush border membrane;GO:0030054//cell junction;GO:0043204//perikaryon;GO:0005768//endosome;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0045202//synapse;GO:0055037//recycling endosome;GO:0034705//potassium channel complex;GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex","GO:0005267//potassium channel activity;GO:0005242//inward rectifier potassium channel activity;GO:0042802//identical protein binding;GO:0005272//sodium channel activity;GO:0022841//potassium ion leak channel activity","GO:0035094//response to nicotine;GO:0006813//potassium ion transport;GO:0061337//cardiac conduction;GO:0035725//sodium ion transmembrane transport;GO:0030322//stabilization of membrane potential;GO:0071805//potassium ion transmembrane transport;GO:0060075//regulation of resting membrane potential","K04912//potassium channel subfamily K member 1","NP_002236.1//potassium channel subfamily K member 1 [Homo sapiens]","3//A2MP1"]
[2631,2017,29.98,22.23,-0.431492434920869,{"v":1.27861851941581e-07,"d":"1.28E-07"},"*",{"v":1.863418e-08,"d":"1.86E-08"},"NIPSNAP2","GO:0016020//membrane;GO:0005887//integral component of plasma membrane;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane","NA","GO:0006119//oxidative phosphorylation;GO:2000984//negative regulation of ATP citrate synthase activity;GO:0006754//ATP biosynthetic process;GO:1901843//positive regulation of high voltage-gated calcium channel activity","K13174//THO complex subunit 5;K19269//phosphoglycolate phosphatase [EC:3.1.3.18 3.1.3.48]","NP_001474.1//protein NipSnap homolog 2 isoform 1 [Homo sapiens];NP_001189398.1//protein NipSnap homolog 2 isoform 2 [Homo sapiens]","1//3;2//1"]
[83988,3586,0.89,0.66,-0.431339311607944,0.381480888176353,"*",0.238336,"NCALD","GO:0070062//extracellular exosome;GO:0030130//clathrin coat of trans-Golgi network vesicle;GO:0005829//cytosol;GO:0005622//intracellular","GO:0015276//ligand-gated ion channel activity;GO:0015631//tubulin binding;GO:0003779//actin binding;GO:0030276//clathrin binding;GO:0043014//alpha-tubulin binding;GO:0005509//calcium ion binding","GO:0003073//regulation of systemic arterial blood pressure;GO:0019722//calcium-mediated signaling;GO:0016192//vesicle-mediated transport","K19695//neurocalcin delta","NP_776823.1//neurocalcin-delta [Bos taurus]","1//3;2//1"]
[129450,5384,3.8,2.82,-0.430304255932154,6.04100060243717E-3,"*",1.986186E-3,"TYW5","GO:0005737//cytoplasm","GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;GO:0005506//iron ion binding;GO:0102524//tRNAPhe (7-(3-amino-3-carboxypropyl)wyosine37-C2)-hydroxylase activity;GO:0000049//tRNA binding;GO:0042803//protein homodimerization activity","GO:0006400//tRNA modification;GO:0031591//wybutosine biosynthetic process","K18066//tRNA wybutosine-synthesizing protein 5 [EC:1.14.11.42]","NP_001034782.1//tRNA wybutosine-synthesizing protein 5 [Homo sapiens]","2//1"]
[8645,3800,1.32,0.98,-0.429684275243245,0.234519506530749,"*",0.1310602,"KCNK5","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane","GO:0005249//voltage-gated potassium channel activity;GO:0005267//potassium channel activity;GO:0022841//potassium ion leak channel activity","GO:0006813//potassium ion transport;GO:0007588//excretion;GO:0071805//potassium ion transmembrane transport;GO:0030322//stabilization of membrane potential","K04916//potassium channel subfamily K member 5","NP_003731.1//potassium channel subfamily K member 5 [Homo sapiens]","3//A2MP1"]
[55568,5966,41.26,30.64,-0.429327523961527,{"v":7.60732899619772e-26,"d":"7.61E-26"},"*",{"v":2.50498E-27,"d":"2.50E-27"},"GALNT10","GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0004653//polypeptide N-acetylgalactosaminyltransferase activity;GO:0030246//carbohydrate binding","GO:0016266//O-glycan processing","K00710//polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41]","BAD21405.1//mFLJ00205 protein, partial [Mus musculus]","3//A2MP1"]
[23390,4609,3.31,2.46,-0.428172901467978,0.0158224940206186,"*",0.0057648,"ZDHHC17","GO:0043231//intracellular membrane-bounded organelle;GO:0030054//cell junction;GO:0030660//Golgi-associated vesicle membrane;GO:0000139//Golgi membrane;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0042734//presynaptic membrane;GO:0030659//cytoplasmic vesicle membrane","GO:0016409//palmitoyltransferase activity;GO:0042802//identical protein binding;GO:0004871//signal transducer activity;GO:0015095//magnesium ion transmembrane transporter activity;GO:0019706//protein-cysteine S-palmitoyltransferase activity","GO:0018345//protein palmitoylation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0042953//lipoprotein transport","K20032//palmitoyltransferase ZDHHC13/17 [EC:2.3.1.225]","XP_012297503.1//palmitoyltransferase ZDHHC17 [Aotus nancymaae];NP_056151.2//palmitoyltransferase ZDHHC17 [Homo sapiens]","1//3;3//A2MP1"]
[51068,2769,9.66,7.18,-0.428039345012722,0.00140072577535916,"*",0.000402838,"NMD3","GO:0016020//membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0030674//protein binding, bridging;GO:0043023//ribosomal large subunit binding","GO:0000055//ribosomal large subunit export from nucleus;GO:1902680//positive regulation of RNA biosynthetic process;GO:1904751//positive regulation of protein localization to nucleolus;GO:0015031//protein transport;GO:0032092//positive regulation of protein binding","K07562//nonsense-mediated mRNA decay protein 3","NP_057022.2//60S ribosomal export protein NMD3 isoform 2 [Homo sapiens];NP_001307156.1//60S ribosomal export protein NMD3 isoform 1 [Homo sapiens]","1//3;4"]
[79896,3787,2.93,2.18,-0.426572529645322,0.0508157859628428,"*",0.0215746,"THNSL1","NA","NA","NA","K06245//laminin, beta 4;K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K02927//large subunit ribosomal protein L40e;K15696//RING finger protein 113B;K17985//activating molecule in BECN1-regulated autophagy protein 1","NP_079114.3//threonine synthase-like 1 [Homo sapiens]",4]
[23299,5446,8.85,6.59,-0.425398989962308,{"v":3.74633150786607E-7,"d":"3.75E-07"},"*",{"v":5.81392E-8,"d":"5.81E-08"},"BICD2","GO:0005856//cytoskeleton;GO:0005643//nuclear pore;GO:0005635//nuclear envelope;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0031410//cytoplasmic vesicle;GO:0005642//annulate lamellae;GO:0005886//plasma membrane","GO:0051959//dynein light intermediate chain binding;GO:0070840//dynein complex binding;GO:0034452//dynactin binding;GO:0017137//Rab GTPase binding","GO:0051642//centrosome localization;GO:0000042//protein targeting to Golgi;GO:0072393//microtubule anchoring at microtubule organizing center;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0072385//minus-end-directed organelle transport along microtubule;GO:0051028//mRNA transport","K18739//protein bicaudal D","NP_001003800.1//protein bicaudal D homolog 2 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[5411,3606,26.99,20.1,-0.42522947540056,{"v":1.6229192720147e-10,"d":"1.62E-10"},"*",{"v":1.659088e-11,"d":"1.66E-11"},"PNN","NA","NA","NA","K13114//pinin","XP_019569216.1//PREDICTED: pinin [Rhinolophus sinicus]","3//A2MP1"]
[643338,2503,0.51,0.38,-0.42449782852791,0.617247559202814,"*",0.461448,"C15orf62","GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0017049//GTP-Rho binding;GO:0005096//GTPase activator activity","GO:0007266//Rho protein signal transduction;GO:0031274//positive regulation of pseudopodium assembly;GO:0030838//positive regulation of actin filament polymerization;GO:0008360//regulation of cell shape","NA","XP_003935755.1//PREDICTED: uncharacterized protein C15orf62 homolog, mitochondrial [Saimiri boliviensis boliviensis]","2//1"]
[11138,4232,18.81,14.02,-0.424013499512572,{"v":1.22311139659699e-08,"d":"1.22E-08"},"*",{"v":1.575022E-9,"d":"1.58E-09"},"TBC1D8","GO:0016020//membrane;GO:0012505//endomembrane system;GO:0005622//intracellular","GO:0017137//Rab GTPase binding;GO:0005096//GTPase activator activity","GO:0006886//intracellular protein transport;GO:0008015//blood circulation;GO:0090630//activation of GTPase activity;GO:0031338//regulation of vesicle fusion;GO:0008284//positive regulation of cell proliferation","K19951//TBC1 domain family member 8/9","NP_001317277.1//TBC1 domain family member 8 isoform 1 [Homo sapiens];NP_001095896.1//TBC1 domain family member 8 isoform 2 [Homo sapiens]","1//3;2//1"]
[146723,2525,0.59,0.44,-0.423211430724544,0.64677355594088,"*",0.490364,"C17orf77","GO:0005576//extracellular region","NA","NA","K16506//protocadherin Fat 1/2/3;K01368//cathepsin S [EC:3.4.22.27];K08857//NIMA (never in mitosis gene a)-related kinase 1/4/5 [EC:2.7.11.1]","NP_689673.2//uncharacterized protein C17orf77 [Homo sapiens]","1//3;2//1"]
[25853,3688,27.29,20.36,-0.422634833198445,{"v":9.90638533249686e-11,"d":"9.91E-11"},"*",{"v":9.8853e-12,"d":"9.89E-12"},"DCAF12","GO:0080008//Cul4-RING E3 ubiquitin ligase complex;GO:0005813//centrosome;GO:0005737//cytoplasm","NA","GO:0016567//protein ubiquitination","K11803//WD repeat-containing protein 40A","ELR51095.1//DDB1- and CUL4-associated factor 12, partial [Bos mutus]","3//A2MP1"]
[687,5208,0.67,0.5,-0.422233000683048,0.353884025043621,"*",0.215844,"KLF9","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0010839//negative regulation of keratinocyte proliferation;GO:0007623//circadian rhythm;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0071387//cellular response to cortisol stimulus;GO:0006351//transcription, DNA-templated;GO:0097067//cellular response to thyroid hormone stimulus","K09208//krueppel-like factor 9/13/14/16","NP_001197.1//Krueppel-like factor 9 [Homo sapiens]","2//1"]
[79786,7571,3.99,2.98,-0.421076415760184,0.000608976077606358,"*",0.00016309,"KLHL36","GO:0031463//Cul3-RING ubiquitin ligase complex","NA","GO:0016567//protein ubiquitination","K13958//kelch-like protein 36","NP_001290380.1//kelch-like protein 36 isoform 2 [Homo sapiens];XP_016785783.1//PREDICTED: kelch-like protein 36 isoform X3 [Pan troglodytes]","1//3;3//A2MP1"]
[24137,4504,13.33,9.97,-0.419011370690777,{"v":1.2285004375e-06,"d":"1.23E-06"},"*",{"v":2.06724e-07,"d":"2.07E-07"},"KIF4A","GO:0016020//membrane;GO:0045171//intercellular bridge;GO:0005654//nucleoplasm;GO:0030496//midbody;GO:0005871//kinesin complex","GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0008574//ATP-dependent microtubule motor activity, plus-end-directed","GO:0000281//mitotic cytokinesis;GO:0007018//microtubule-based movement;GO:0051256//mitotic spindle midzone assembly","K10395//kinesin family member 4/21/27","XP_007990177.1//PREDICTED: chromosome-associated kinesin KIF4A [Chlorocebus sabaeus]",4]
[91351,6667,2.46,1.84,-0.418952549282227,0.0190112034417981,"*",0.00709558,"DDX60L","NA","GO:0003723//RNA binding;GO:0005524//ATP binding;GO:0004386//helicase activity;GO:0003676//nucleic acid binding","NA","K20103//ATP-dependent RNA helicase DDX60 [EC:3.6.4.13]","NP_001278439.1//probable ATP-dependent RNA helicase DDX60-like isoform 2 [Homo sapiens];Q5H9U9.2//RecName: Full=Probable ATP-dependent RNA helicase DDX60-like; AltName: Full=DEAD box protein 60-like","1//3;2//1"]
[286075,2452,4.45,3.33,-0.418283158782498,0.0836733543172414,"*",0.0379762,"ZNF707","GO:0005622//intracellular","GO:0046872//metal ion binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","EGW13772.1//Zinc finger protein 623 [Cricetulus griseus]","1//3;3//A2MP1"]
[10057,4524,5.13,3.84,-0.417852514885898,0.000307474336293724,"*",{"v":7.75904e-05,"d":"7.76E-05"},"ABCC5","GO:0016020//membrane;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane","GO:0043225//ATPase-coupled anion transmembrane transporter activity;GO:0005524//ATP binding;GO:0042626//ATPase activity, coupled to transmembrane movement of substances;GO:0008514//organic anion transmembrane transporter activity","GO:0006810//transport;GO:0055085//transmembrane transport;GO:0030213//hyaluronan biosynthetic process","K05668//ATP-binding cassette, subfamily C (CFTR/MRP), member 5","XP_005546569.1//PREDICTED: multidrug resistance-associated protein 5 isoform X1 [Macaca fascicularis];NP_005679.2//multidrug resistance-associated protein 5 isoform 1 [Homo sapiens];XP_017721361.1//PREDICTED: multidrug resistance-associated protein 5-like isoform X2 [Rhinopithecus bieti]","1//3;3//A2MP1;2//1"]
[7039,4339,2.27,1.7,-0.417157551153213,0.0813594914728682,"*",0.0367936,"TGFA","GO:0016323//basolateral plasma membrane;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0031410//cytoplasmic vesicle;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0048471//perinuclear region of cytoplasm;GO:0000139//Golgi membrane;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0012507//ER to Golgi transport vesicle membrane","GO:0008083//growth factor activity;GO:0005154//epidermal growth factor receptor binding","GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0048208//COPII vesicle coating;GO:0051781//positive regulation of cell division;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0045840//positive regulation of mitotic nuclear division;GO:0042493//response to drug;GO:0000187//activation of MAPK activity;GO:0001525//angiogenesis;GO:0045741//positive regulation of epidermal growth factor-activated receptor activity;GO:0042060//wound healing;GO:0072574//hepatocyte proliferation;GO:0043066//negative regulation of apoptotic process;GO:0060749//mammary gland alveolus development;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0050679//positive regulation of epithelial cell proliferation;GO:0008284//positive regulation of cell proliferation","K08774//transforming growth factor, alpha","NP_001295088.1//protransforming growth factor alpha isoform 4 precursor [Homo sapiens];XP_007938333.1//PREDICTED: protransforming growth factor alpha [Orycteropus afer afer];NP_001295087.1//protransforming growth factor alpha isoform 3 precursor [Homo sapiens]","1//3;3//A2MP1;2//1"]
[4528,2665,16.11,12.07,-0.416530817951547,{"v":7.82003482333425e-05,"d":"7.82E-05"},"*",{"v":1.770694e-05,"d":"1.77E-05"},"MTIF2","GO:0005654//nucleoplasm;GO:0005739//mitochondrion","GO:0003743//translation initiation factor activity;GO:0008135//translation factor activity, RNA binding;GO:0003723//RNA binding;GO:0043024//ribosomal small subunit binding;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0006446//regulation of translational initiation;GO:0070124//mitochondrial translational initiation;GO:0032790//ribosome disassembly","K02519//translation initiation factor IF-2","XP_011812837.1//PREDICTED: translation initiation factor IF-2, mitochondrial [Colobus angolensis palliatus];NP_002444.2//translation initiation factor IF-2, mitochondrial isoform a precursor [Homo sapiens]","1//3;2//1"]
[8801,2363,14.81,11.1,-0.41601196405138,3.98408938222438E-4,"*",0.0001027074,"SUCLG2","GO:0005759//mitochondrial matrix;GO:0045244//succinate-CoA ligase complex (GDP-forming);GO:0005739//mitochondrion;GO:0005886//plasma membrane","GO:0004775//succinate-CoA ligase (ADP-forming) activity;GO:0000287//magnesium ion binding;GO:0005524//ATP binding;GO:0019003//GDP binding;GO:0046982//protein heterodimerization activity;GO:0046872//metal ion binding;GO:0005525//GTP binding;GO:0004776//succinate-CoA ligase (GDP-forming) activity","GO:0006099//tricarboxylic acid cycle;GO:0006104//succinyl-CoA metabolic process;GO:0006105//succinate metabolic process","K01900//succinyl-CoA synthetase beta subunit [EC:6.2.1.4 6.2.1.5]","NP_003839.2//succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial isoform 2 precursor [Homo sapiens];NP_001171070.1//succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[9254,5461,0.28,0.21,-0.415037499278844,0.56395981877918,"*",0.408336,"CACNA2D2","GO:0005886//plasma membrane;GO:0005891//voltage-gated calcium channel complex","GO:0046872//metal ion binding;GO:0005245//voltage-gated calcium channel activity","GO:0007528//neuromuscular junction development;GO:0046622//positive regulation of organ growth;GO:0061337//cardiac conduction;GO:0060024//rhythmic synaptic transmission;GO:0040014//regulation of multicellular organism growth;GO:0048747//muscle fiber development;GO:0050796//regulation of insulin secretion","K04859//voltage-dependent calcium channel alpha-2/delta-2","NP_001005505.1//voltage-dependent calcium channel subunit alpha-2/delta-2 isoform a precursor [Homo sapiens];XP_011737764.1//PREDICTED: voltage-dependent calcium channel subunit alpha-2/delta-2 isoform X1 [Macaca nemestrina];XP_011737765.1//PREDICTED: voltage-dependent calcium channel subunit alpha-2/delta-2 isoform X2 [Macaca nemestrina]","1//3;3//A2MP1;2//1"]
[4855,6762,0.04,0.03,-0.415037499278844,1.01600911900057,"*",0.997882,"NOTCH4","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000139//Golgi membrane;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane","GO:0004872//receptor activity;GO:0005509//calcium ion binding;GO:0046982//protein heterodimerization activity","GO:0006355//regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0001763//morphogenesis of a branching structure;GO:0030097//hemopoiesis;GO:0045602//negative regulation of endothelial cell differentiation;GO:0030879//mammary gland development;GO:0001709//cell fate determination;GO:0001886//endothelial cell morphogenesis;GO:0030154//cell differentiation;GO:0007221//positive regulation of transcription of Notch receptor target;GO:0007220//Notch receptor processing;GO:0007275//multicellular organism development;GO:0009790//embryo development;GO:0045596//negative regulation of cell differentiation;GO:0050793//regulation of developmental process;GO:0001569//branching involved in blood vessel morphogenesis;GO:0007219//Notch signaling pathway;GO:0006367//transcription initiation from RNA polymerase II promoter","K20996//Notch 4","NP_004548.3//neurogenic locus notch homolog protein 4 preproprotein [Homo sapiens]","3//A2MP1"]
[9940,5635,0.04,0.03,-0.415037499278844,0.782819122991611,"*",0.689316,"DLEC1","GO:0005829//cytosol;GO:0005737//cytoplasm","NA","GO:0008285//negative regulation of cell proliferation","K17570//hydrocephalus-inducing protein","NP_031361.2//deleted in lung and esophageal cancer protein 1 isoform DLEC1-N1 [Homo sapiens];NP_031363.2//deleted in lung and esophageal cancer protein 1 isoform DLEC1-S3 [Homo sapiens];NP_001308082.1//deleted in lung and esophageal cancer protein 1 isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[5669,1895,0.32,0.24,-0.415037499278844,0.582329381930185,"*",0.426084,"PSG1","GO:0005576//extracellular region","NA","GO:0007565//female pregnancy;GO:0050900//leukocyte migration","K06500//pregnancy specific beta-1-glycoprotein","NP_001284702.1//pregnancy-specific beta-1-glycoprotein 1 isoform 4 precursor [Homo sapiens];NP_001317453.1//pregnancy-specific beta-1-glycoprotein 1 isoform 5 precursor [Homo sapiens];NP_008836.2//pregnancy-specific beta-1-glycoprotein 1 isoform 1 precursor [Homo sapiens];NP_001171755.1//pregnancy-specific beta-1-glycoprotein 1 isoform 3 precursor [Homo sapiens];NP_001171754.1//pregnancy-specific beta-1-glycoprotein 1 isoform 2 precursor [Homo sapiens]","1//3;2//1"]
[124872,1806,0.36,0.27,-0.415037499278844,0.612608866952069,"*",0.456868,"B4GALNT2","GO:0030173//integral component of Golgi membrane;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0008376//acetylgalactosaminyltransferase activity","GO:0006047//UDP-N-acetylglucosamine metabolic process;GO:0022408//negative regulation of cell-cell adhesion;GO:0018279//protein N-linked glycosylation via asparagine;GO:0030259//lipid glycosylation;GO:0019276//UDP-N-acetylgalactosamine metabolic process","K09655//beta-1,4-N-acetylgalactosaminyltransferase 2 [EC:2.4.1.-]","NP_001152859.1//beta-1,4 N-acetylgalactosaminyltransferase 2 isoform b [Homo sapiens];NP_703147.2//beta-1,4 N-acetylgalactosaminyltransferase 2 isoform a [Homo sapiens];AAM34756.1//beta-4-N-acetylgalactosaminyltransferase [Homo sapiens]","1//3;2//1"]
[222658,5476,5.92,4.44,-0.415037499278844,{"v":4.942017864E-5,"d":"4.94E-05"},"*",{"v":1.082826E-5,"d":"1.08E-05"},"KCTD20","GO:0005737//cytoplasm","NA","GO:0042327//positive regulation of phosphorylation","K10482//BTB/POZ domain-containing protein 10","NP_001273508.1//BTB/POZ domain-containing protein KCTD20 isoform b [Homo sapiens];NP_775833.2//BTB/POZ domain-containing protein KCTD20 isoform a [Homo sapiens];XP_527371.1//PREDICTED: BTB/POZ domain-containing protein KCTD20 isoform X1 [Pan troglodytes]","4;1//3"]
[51193,2999,5.77,4.33,-0.414204293918757,0.0162204903921904,"*",0.0059291,"ZNF639","GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0043621//protein self-association;GO:0044212//transcription regulatory region DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0043922//negative regulation by host of viral transcription;GO:0030307//positive regulation of cell growth;GO:0046718//viral entry into host cell;GO:0043923//positive regulation by host of viral transcription","K09228//KRAB domain-containing zinc finger protein","NP_057415.1//zinc finger protein 639 [Homo sapiens]","1//3;2//1"]
[1491,2140,1.25,0.94,-0.41119543298445,0.448666874895046,"*",0.301068,"CTH","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0004123//cystathionine gamma-lyase activity;GO:0044540//L-cystine L-cysteine-lyase (deaminating);GO:0042802//identical protein binding;GO:0016846//carbon-sulfur lyase activity;GO:0080146//L-cysteine desulfhydrase activity;GO:0005516//calmodulin binding;GO:0030170//pyridoxal phosphate binding;GO:0047982//homocysteine desulfhydrase activity;GO:0003962//cystathionine gamma-synthase activity","GO:0019346//transsulfuration;GO:0051289//protein homotetramerization;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0000098//sulfur amino acid catabolic process;GO:0071266//'de novo' L-methionine biosynthetic process;GO:1904831//positive regulation of aortic smooth muscle cell differentiation;GO:0044524//protein sulfhydration;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:1990830//cellular response to leukemia inhibitory factor;GO:0019343//cysteine biosynthetic process via cystathionine;GO:0006534//cysteine metabolic process;GO:0018272//protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine;GO:0070814//hydrogen sulfide biosynthetic process;GO:0019344//cysteine biosynthetic process;GO:0030968//endoplasmic reticulum unfolded protein response;GO:2001234//negative regulation of apoptotic signaling pathway","K01758//cystathionine gamma-lyase [EC:4.4.1.1]","NP_714964.2//cystathionine gamma-lyase isoform 2 [Homo sapiens];NP_001177392.1//cystathionine gamma-lyase isoform 3 [Homo sapiens];NP_001893.2//cystathionine gamma-lyase isoform 1 [Homo sapiens]","1//3;4;5"]
[10110,1913,9.16,6.89,-0.410843615392653,0.00844121465930018,"*",0.0028694,"SGK2","GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005622//intracellular","GO:0004674//protein serine/threonine kinase activity;GO:0015459//potassium channel regulator activity;GO:0005524//ATP binding;GO:0017080//sodium channel regulator activity;GO:0005246//calcium channel regulator activity;GO:0017081//chloride channel regulator activity","GO:0001558//regulation of cell growth;GO:0034220//ion transmembrane transport;GO:0042127//regulation of cell proliferation;GO:0006468//protein phosphorylation;GO:0032411//positive regulation of transporter activity;GO:0035556//intracellular signal transduction;GO:0006979//response to oxidative stress;GO:0018105//peptidyl-serine phosphorylation;GO:0042981//regulation of apoptotic process","K13303//serum/glucocorticoid-regulated kinase 2 [EC:2.7.11.1]","NP_057360.2//serine/threonine-protein kinase Sgk2 isoform beta [Homo sapiens]","1//3;3//A2MP1;2//1"]
[66036,7421,2.99,2.25,-0.410220482981068,0.00528119370777842,"*",0.0017129,"MTMR9","GO:0005829//cytosol","GO:0030234//enzyme regulator activity;GO:0004438//phosphatidylinositol-3-phosphatase activity;GO:0052629//phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity","GO:0006661//phosphatidylinositol biosynthetic process","K18084//myotubularin-related protein 9","NP_056273.2//myotubularin-related protein 9 [Homo sapiens]","3//A2MP1"]
[6483,4450,12.01,9.04,-0.409841473290446,{"v":7.14270831227258e-06,"d":"7.14E-06"},"*",{"v":1.351722e-06,"d":"1.35E-06"},"ST3GAL2","GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane","GO:0008373//sialyltransferase activity","GO:0006486//protein glycosylation","K03368//beta-galactoside alpha-2,3-sialyltransferase (sialyltransferase 4B) [EC:2.4.99.4]","XP_006974157.1//PREDICTED: CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 [Peromyscus maniculatus bairdii]","3//A2MP1"]
[114804,4851,10.8,8.13,-0.409704054975803,{"v":7.36122237594979e-06,"d":"7.36E-06"},"*",{"v":1.394918e-06,"d":"1.39E-06"},"RNF157","NA","GO:0046872//metal ion binding","NA","K10604//E3 ubiquitin-protein ligase MGRN1 [EC:2.3.2.27]","NP_443148.1//RING finger protein 157 isoform 1 [Homo sapiens];NP_001317430.1//RING finger protein 157 isoform 2 [Homo sapiens]","1//3;2//1"]
[23300,4860,13.95,10.51,-0.408502452754371,{"v":2.97758229971417E-7,"d":"2.98E-07"},"*",{"v":4.56498e-08,"d":"4.56E-08"},"ATMIN","GO:0016604//nuclear body","GO:0070840//dynein complex binding;GO:0046872//metal ion binding;GO:0044212//transcription regulatory region DNA binding;GO:0003676//nucleic acid binding","GO:1902857//positive regulation of non-motile cilium assembly;GO:0006351//transcription, DNA-templated;GO:0044458//motile cilium assembly;GO:0006974//cellular response to DNA damage stimulus;GO:0045893//positive regulation of transcription, DNA-templated","K12581//CCR4-NOT transcription complex subunit 7/8;K11447//histone demethylase [EC:1.14.11.-];K17985//activating molecule in BECN1-regulated autophagy protein 1;K15696//RING finger protein 113B","NP_056066.2//ATM interactor isoform 1 [Homo sapiens];AAH02701.2//ATMIN protein, partial [Homo sapiens]","1//3;2//1"]
[9086,1413,1.26,0.95,-0.407424315168969,0.493296860699682,"*",0.339848,"EIF1AY","NA","GO:0003743//translation initiation factor activity;GO:0043023//ribosomal large subunit binding","NA","K03236//translation initiation factor 1A","XP_011832202.1//PREDICTED: eukaryotic translation initiation factor 1A, Y-chromosomal-like [Mandrillus leucophaeus];OBS60797.1//hypothetical protein A6R68_08078, partial [Neotoma lepida]","1//3;3//A2MP1"]
[387893,2682,27.56,20.78,-0.407380233800079,{"v":2.40372892307692e-08,"d":"2.40E-08"},"*",{"v":3.18862e-09,"d":"3.19E-09"},"KMT5A","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005694//chromosome","GO:0016279//protein-lysine N-methyltransferase activity;GO:0016278//lysine N-methyltransferase activity;GO:0003714//transcription corepressor activity;GO:0002039//p53 binding;GO:0042799//histone methyltransferase activity (H4-K20 specific);GO:0018024//histone-lysine N-methyltransferase activity","GO:1901796//regulation of signal transduction by p53 class mediator;GO:0043516//regulation of DNA damage response, signal transduction by p53 class mediator;GO:0018026//peptidyl-lysine monomethylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0051301//cell division;GO:0006351//transcription, DNA-templated;GO:0007049//cell cycle","K11428//histone-lysine N-methyltransferase SETD8 [EC:2.1.1.43]","NP_065115.3//N-lysine methyltransferase KMT5A isoform 1 [Homo sapiens];NP_001311433.1//N-lysine methyltransferase KMT5A isoform 2 [Homo sapiens];Q9NQR1.3//RecName: Full=N-lysine methyltransferase KMT5A; AltName: Full=H4-K20-HMTase KMT5A; AltName: Full=Histone-lysine N-methyltransferase KMT5A; AltName: Full=Lysine N-methyltransferase 5A; AltName: Full=Lysine-specific methylase 5A; AltName: Full=PR/SET domain-containing protein 07; Short=PR-Set7; Short=PR/SET07; AltName: Full=SET domain-containing protein 8;EAW98406.1//SET domain containing (lysine methyltransferase) 8, isoform CRA_a, partial [Homo sapiens]","1//3;4"]
[64781,4445,10.8,8.15,-0.406159347932391,{"v":2.642123477429e-05,"d":"2.64E-05"},"*",{"v":5.53268e-06,"d":"5.53E-06"},"CERK","GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005886//plasma membrane","GO:0000287//magnesium ion binding;GO:0003951//NAD+ kinase activity;GO:0102773//dihydroceramide kinase activity;GO:0005524//ATP binding;GO:0001729//ceramide kinase activity","GO:0006687//glycosphingolipid metabolic process;GO:0006672//ceramide metabolic process","K04715//ceramide kinase [EC:2.7.1.138]","NP_073603.2//ceramide kinase [Homo sapiens]",5]
[6041,4258,1.06,0.8,-0.405992359675837,0.28630919245283,"*",0.16624,"RNASEL","GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0016363//nuclear matrix","GO:0003723//RNA binding;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0004521//endoribonuclease activity;GO:0046872//metal ion binding;GO:0004672//protein kinase activity;GO:0043021//ribonucleoprotein complex binding;GO:0004540//ribonuclease activity;GO:0019843//rRNA binding","GO:2001275//positive regulation of glucose import in response to insulin stimulus;GO:0006397//mRNA processing;GO:0060337//type I interferon signaling pathway;GO:0006468//protein phosphorylation;GO:0051607//defense response to virus;GO:0006364//rRNA processing;GO:0045444//fat cell differentiation;GO:0045071//negative regulation of viral genome replication;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0060338//regulation of type I interferon-mediated signaling pathway;GO:0043488//regulation of mRNA stability","K01165//ribonuclease L","NP_066956.1//2-5A-dependent ribonuclease [Homo sapiens]","3//A2MP1"]
[441549,1330,0.49,0.37,-0.405256478486259,0.723442971411599,"*",0.609904,"CDNF","GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum","GO:0008083//growth factor activity","GO:0031175//neuron projection development;GO:0071542//dopaminergic neuron differentiation","K13190//RNA-binding protein 15","NP_001025125.2//cerebral dopamine neurotrophic factor precursor [Homo sapiens]","2//1"]
[23524,9379,100.25,75.73,-0.404665402857668,{"v":2.35756166477876e-87,"d":"2.36E-87"},"*",{"v":1.667738e-89,"d":"1.67E-89"},"SRRM2","GO:0005654//nucleoplasm;GO:0016607//nuclear speck;GO:0015030//Cajal body;GO:0071013//catalytic step 2 spliceosome","GO:0003723//RNA binding;GO:0070742//C2H2 zinc finger domain binding;GO:0047485//protein N-terminus binding","GO:0000398//mRNA splicing, via spliceosome","K13172//serine/arginine repetitive matrix protein 2","NP_057417.3//serine/arginine repetitive matrix protein 2 [Homo sapiens]","3//A2MP1"]
[83932,3663,3.98,3.01,-0.403004943783947,0.0313552480731054,"*",0.01245848,"SPRTN","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016607//nuclear speck;GO:0005694//chromosome","GO:0070530//K63-linked polyubiquitin modification-dependent protein binding;GO:0043130//ubiquitin binding;GO:0046872//metal ion binding;GO:0003677//DNA binding","GO:0019985//translesion synthesis;GO:0070987//error-free translesion synthesis;GO:0006281//DNA repair;GO:0009411//response to UV;GO:0031398//positive regulation of protein ubiquitination;GO:0006974//cellular response to DNA damage stimulus","K08049//adenylate cyclase 9 [EC:4.6.1.1]","NP_001010984.1//sprT-like domain-containing protein Spartan isoform b [Homo sapiens];NP_114407.3//sprT-like domain-containing protein Spartan isoform a [Homo sapiens];XP_011542591.1//PREDICTED: sprT-like domain-containing protein Spartan isoform X2 [Homo sapiens]","6;3//A2MP1;2//1"]
[224,3718,64.6,48.87,-0.402585060334613,{"v":2.93903689757576e-22,"d":"2.94E-22"},"*",{"v":1.214326e-23,"d":"1.21E-23"},"ALDH3A2","GO:0016021//integral component of membrane","GO:0004030//aldehyde dehydrogenase [NAD(P)+] activity","GO:0006081//cellular aldehyde metabolic process","K00128//aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]","XP_011932581.1//PREDICTED: fatty aldehyde dehydrogenase isoform X2 [Cercocebus atys];XP_011932579.1//PREDICTED: fatty aldehyde dehydrogenase isoform X1 [Cercocebus atys]","1//3;2//1"]
[7798,8425,6.42,4.86,-0.401616983516522,{"v":1.03749200772947E-5,"d":"1.04E-05"},"*",{"v":2.01666e-06,"d":"2.02E-06"},"LUZP1","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus","NA","GO:0021503//neural fold bending;GO:0060840//artery development;GO:0003281//ventricular septum development","K10352//myosin heavy chain;K12875//apoptotic chromatin condensation inducer in the nucleus","NP_361013.3//leucine zipper protein 1 [Homo sapiens]","1//3;3//A2MP1"]
[9172,5018,0.33,0.25,-0.400537929583729,0.578702636731183,"*",0.421148,"MYOM2","NA","NA","NA","K12567//titin [EC:2.7.11.1]","XP_007959780.1//PREDICTED: myomesin-2 isoform X2 [Chlorocebus sabaeus]","3//A2MP1"]
[23029,2228,21.96,16.64,-0.400222620864106,{"v":3.3528526056338e-05,"d":"3.35E-05"},"*",{"v":7.1532e-06,"d":"7.15E-06"},"RBM34","NA","NA","NA","K14837//nucleolar protein 12;K19195//AT-rich interactive domain-containing protein 4B","XP_018887532.1//PREDICTED: RNA-binding protein 34 isoform X2 [Gorilla gorilla gorilla]","1//3;3//A2MP1"]
[83860,3298,5.79,4.39,-0.399342408453878,0.0140416496220171,"*",0.00504652,"TAF3","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0005669//transcription factor TFIID complex","GO:0046872//metal ion binding;GO:0002039//p53 binding","GO:0006368//transcription elongation from RNA polymerase II promoter;GO:1901796//regulation of signal transduction by p53 class mediator;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0043433//negative regulation of DNA binding transcription factor activity;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0051457//maintenance of protein location in nucleus","K14650//transcription initiation factor TFIID subunit 3","XP_011518043.1//PREDICTED: transcription initiation factor TFIID subunit 3 isoform X1 [Homo sapiens]","3//A2MP1"]
[7803,5093,65.18,49.46,-0.398167112348627,{"v":4.09460732258064e-30,"d":"4.09E-30"},"*",{"v":1.11247e-31,"d":"1.11E-31"},"PTP4A1","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0009898//cytoplasmic side of plasma membrane;GO:0005819//spindle;GO:0005769//early endosome;GO:0005886//plasma membrane","GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0004727//prenylated protein tyrosine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity","GO:0030335//positive regulation of cell migration;GO:0007275//multicellular organism development;GO:0007049//cell cycle","K18041//protein tyrosine phosphatase type IVA [EC:3.1.3.48]","EDL14423.1//protein tyrosine phosphatase 4a1, isoform CRA_b, partial [Mus musculus]",4]
[953,12513,3.53,2.68,-0.397435182813408,1.03744373101952E-4,"*",{"v":2.3952E-5,"d":"2.40E-05"},"ENTPD1","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0102491//dGTP phosphohydrolase activity;GO:0005524//ATP binding;GO:0102485//dATP phosphohydrolase activity;GO:0102490//8-oxo-dGTP phosphohydrolase activity;GO:0102486//dCTP phosphohydrolase activity;GO:0102488//dTTP phosphohydrolase activity;GO:0016787//hydrolase activity;GO:0102487//dUTP phosphohydrolase activity;GO:0017111//nucleoside-triphosphatase activity;GO:0102489//GTP phosphohydrolase activity;GO:0017110//nucleoside-diphosphatase activity","GO:0007155//cell adhesion;GO:0007596//blood coagulation;GO:0034656//nucleobase-containing small molecule catabolic process","K01510//apyrase [EC:3.6.1.5]","NP_001157651.1//ectonucleoside triphosphate diphosphohydrolase 1 isoform 4 [Homo sapiens];XP_011806626.1//PREDICTED: ectonucleoside triphosphate diphosphohydrolase 1 isoform X1 [Colobus angolensis palliatus];NP_001307845.1//ectonucleoside triphosphate diphosphohydrolase 1 isoform 7 [Homo sapiens];NP_001091645.1//ectonucleoside triphosphate diphosphohydrolase 1 isoform 2 [Homo sapiens];XP_002821065.1//PREDICTED: ectonucleoside triphosphate diphosphohydrolase 1 isoform X1 [Pongo abelii];NP_001157650.1//ectonucleoside triphosphate diphosphohydrolase 1 isoform 3 [Homo sapiens]","1//3;5"]
[131544,10767,2.62,1.99,-0.396798380993801,0.00195315478385802,"*",0.000578708,"CRYBG3","GO:0043234//protein complex","GO:0051018//protein kinase A binding;GO:0030246//carbohydrate binding","NA","K13596//activin receptor type-2B [EC:2.7.11.30];K16810//TBCC domain-containing protein 1","NP_705833.3//very large A-kinase anchor protein [Homo sapiens]","3//A2MP1"]
[57563,5275,2.75,2.09,-0.395928676331139,0.0169604149097104,"*",0.00623248,"KLHL8","GO:0005654//nucleoplasm;GO:0031463//Cul3-RING ubiquitin ligase complex","NA","GO:0016567//protein ubiquitination;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process","K10446//kelch-like protein 8","NP_065854.3//kelch-like protein 8 isoform 1 [Homo sapiens];NP_001278936.1//kelch-like protein 8 isoform 3 [Homo sapiens];NP_001278935.1//kelch-like protein 8 isoform 2 [Homo sapiens]","4;1//3"]
[81608,2342,17.48,13.29,-0.395364080224424,0.000156789218205598,"*",{"v":3.75238e-05,"d":"3.75E-05"},"FIP1L1","GO:0005654//nucleoplasm;GO:0005847//mRNA cleavage and polyadenylation specificity factor complex","GO:0003723//RNA binding","GO:0006406//mRNA export from nucleus;GO:0098789//pre-mRNA cleavage required for polyadenylation;GO:0000398//mRNA splicing, via spliceosome;GO:0006369//termination of RNA polymerase II transcription;GO:0031124//mRNA 3'-end processing;GO:0006378//mRNA polyadenylation","K14405//pre-mRNA 3'-end-processing factor FIP1","XP_020017369.1//pre-mRNA 3'-end-processing factor FIP1 [Castor canadensis];NP_001128410.1//pre-mRNA 3'-end-processing factor FIP1 isoform 3 [Homo sapiens];NP_001128409.1//pre-mRNA 3'-end-processing factor FIP1 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[54602,4666,4.26,3.24,-0.394859617341213,0.0128758286877193,"*",0.00459448,"NDFIP2","GO:0043231//intracellular membrane-bounded organelle;GO:0005783//endoplasmic reticulum;GO:0032585//multivesicular body membrane;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005739//mitochondrion","GO:0050699//WW domain binding;GO:0004871//signal transducer activity","GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0031398//positive regulation of protein ubiquitination;GO:0051224//negative regulation of protein transport;GO:0010629//negative regulation of gene expression;GO:0032410//negative regulation of transporter activity","NA","XP_009246988.1//PREDICTED: NEDD4 family-interacting protein 2 isoform X1 [Pongo abelii]","1//3;2//1"]
[84861,2637,7.99,6.08,-0.394124179484391,0.0106627311286844,"*",0.003714,"KLHL22","GO:0005827//polar microtubule;GO:0072686//mitotic spindle;GO:0005829//cytosol;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0031463//Cul3-RING ubiquitin ligase complex","NA","GO:0043687//post-translational protein modification;GO:0000070//mitotic sister chromatid segregation;GO:0006513//protein monoubiquitination;GO:0051301//cell division;GO:0007094//mitotic spindle assembly checkpoint","K10459//kelch-like protein 22","XP_016884509.1//PREDICTED: kelch-like protein 22 isoform X3 [Homo sapiens]","3//A2MP1"]
[25926,2638,36.7,27.94,-0.393448042321112,{"v":2.44121506709265e-09,"d":"2.44E-09"},"*",{"v":2.87004e-10,"d":"2.87E-10"},"NOL11","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0034455//t-UTP complex","GO:0003723//RNA binding","GO:0006351//transcription, DNA-templated;GO:0006364//rRNA processing;GO:0030490//maturation of SSU-rRNA;GO:1901838//positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter","K20478//golgin subfamily B member 1","NP_056277.2//nucleolar protein 11 isoform 1 [Homo sapiens];EAW89036.1//nucleolar protein 11, isoform CRA_d [Homo sapiens]","4;1//3"]
[84517,2017,1.51,1.15,-0.392914688380704,0.423687494143415,"*",0.278524,"ACTRT3","GO:0001673//male germ cell nucleus","NA","NA","K12314//actin, alpha cardiac muscle;K10354//actin, alpha skeletal muscle;K05692//actin beta/gamma 1","XP_011916028.1//PREDICTED: actin-related protein T3 [Cercocebus atys]",4]
[540,6418,1.05,0.8,-0.39231742277876,0.154623303631011,"*",0.0789088,"ATP7B","GO:0016020//membrane;GO:0032588//trans-Golgi network membrane;GO:0005770//late endosome;GO:0005887//integral component of plasma membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005802//trans-Golgi network;GO:0000139//Golgi membrane","GO:0004008//copper-exporting ATPase activity;GO:0005524//ATP binding;GO:0019829//cation-transporting ATPase activity;GO:0000166//nucleotide binding;GO:0005507//copper ion binding;GO:0043682//copper-transporting ATPase activity;GO:0005375//copper ion transmembrane transporter activity","GO:0007595//lactation;GO:0006878//cellular copper ion homeostasis;GO:0051208//sequestering of calcium ion;GO:0034220//ion transmembrane transport;GO:0015680//intracellular copper ion transport;GO:0006882//cellular zinc ion homeostasis;GO:0030001//metal ion transport;GO:0046688//response to copper ion;GO:0006825//copper ion transport;GO:0015677//copper ion import","K17686//Cu+-exporting ATPase [EC:3.6.3.54]","NP_000044.2//copper-transporting ATPase 2 isoform a [Homo sapiens];NP_001317507.1//copper-transporting ATPase 2 isoform d [Homo sapiens];NP_001005918.1//copper-transporting ATPase 2 isoform b [Homo sapiens];NP_001317508.1//copper-transporting ATPase 2 isoform e [Homo sapiens];XP_011794355.1//PREDICTED: copper-transporting ATPase 2 isoform X5 [Colobus angolensis palliatus]","1//3;3//A2MP1;2//1"]
[5563,9369,1.47,1.12,-0.39231742277876,0.0480683629927116,"*",0.0202306,"PRKAA2","GO:0031588//nucleotide-activated protein kinase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0005737//cytoplasm","GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005524//ATP binding;GO:0050405//[acetyl-CoA carboxylase] kinase activity;GO:0035174//histone serine kinase activity;GO:0046872//metal ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0047322//[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity;GO:0004679//AMP-activated protein kinase activity;GO:0003682//chromatin binding;GO:0004672//protein kinase activity","GO:0032007//negative regulation of TOR signaling;GO:0010468//regulation of gene expression;GO:0035690//cellular response to drug;GO:0006355//regulation of transcription, DNA-templated;GO:0006950//response to stress;GO:0035404//histone-serine phosphorylation;GO:0035556//intracellular signal transduction;GO:0042149//cellular response to glucose starvation;GO:0007050//cell cycle arrest;GO:0042593//glucose homeostasis;GO:0014850//response to muscle activity;GO:0045821//positive regulation of glycolytic process;GO:0055089//fatty acid homeostasis;GO:0006914//autophagy;GO:0006633//fatty acid biosynthetic process;GO:0031669//cellular response to nutrient levels;GO:0008610//lipid biosynthetic process;GO:0016241//regulation of macroautophagy;GO:0007165//signal transduction;GO:0006468//protein phosphorylation;GO:0006351//transcription, DNA-templated;GO:0006695//cholesterol biosynthetic process;GO:0043066//negative regulation of apoptotic process;GO:0048511//rhythmic process;GO:0010508//positive regulation of autophagy;GO:1901796//regulation of signal transduction by p53 class mediator;GO:0042752//regulation of circadian rhythm;GO:0042304//regulation of fatty acid biosynthetic process;GO:0016239//positive regulation of macroautophagy;GO:0071380//cellular response to prostaglandin E stimulus;GO:0016055//Wnt signaling pathway;GO:2000505//regulation of energy homeostasis;GO:0006853//carnitine shuttle;GO:0016236//macroautophagy","K07198//5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]","NP_006243.2//5'-AMP-activated protein kinase catalytic subunit alpha-2 [Homo sapiens]","3//A2MP1"]
[84899,3924,2.9,2.21,-0.392006530623503,0.101350477602355,"*",0.0474204,"TMTC4","GO:0016021//integral component of membrane","NA","NA","K09667//protein O-GlcNAc transferase [EC:2.4.1.255]","NP_001273382.1//transmembrane and TPR repeat-containing protein 4 isoform 3 [Homo sapiens];NP_001337505.1//transmembrane and TPR repeat-containing protein 4 isoform 6 [Homo sapiens];NP_001337500.1//transmembrane and TPR repeat-containing protein 4 isoform 4 [Homo sapiens];XP_007958982.1//PREDICTED: transmembrane and TPR repeat-containing protein 4 isoform X1 [Chlorocebus sabaeus];NP_116202.2//transmembrane and TPR repeat-containing protein 4 isoform 1 [Homo sapiens]","1//3;4;3//A2MP1;2//1"]
[9262,5324,3.79,2.89,-0.391128355670413,0.0120259379100248,"*",0.00425056,"STK17B","GO:0005634//nucleus;GO:0015629//actin cytoskeleton;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005886//plasma membrane","GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity","GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction;GO:0046777//protein autophosphorylation;GO:2000271//positive regulation of fibroblast apoptotic process;GO:0006915//apoptotic process","K08804//serine/threonine kinase 17 [EC:2.7.11.1]","NP_004217.1//serine/threonine-protein kinase 17B [Homo sapiens]","3//A2MP1"]
[84804,5313,3.33,2.54,-0.390693680299096,0.0241921397267404,"*",0.00931096,"MFSD9","GO:0016021//integral component of membrane","GO:0005215//transporter activity","GO:0055085//transmembrane transport","K08214//MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 18","NP_116107.3//major facilitator superfamily domain-containing protein 9 isoform 1 [Homo sapiens];XP_011812004.1//PREDICTED: major facilitator superfamily domain-containing protein 9 isoform X1 [Colobus angolensis palliatus]","4;1//3"]
[127428,6031,1.9,1.45,-0.389946518316013,0.0880612477099237,"*",0.0404418,"TCEANC2","GO:0005634//nucleus","NA","GO:0006351//transcription, DNA-templated","K01064//wingless-type MMTV integration site family, member 9","XP_012362198.1//PREDICTED: transcription elongation factor A N-terminal and central domain-containing protein 2 isoform X1 [Nomascus leucogenys]","2//1"]
[257407,3595,3.38,2.58,-0.38965218085893,0.0676172804895403,"*",0.029745,"C2orf72","NA","NA","NA","K19475//WAS/WASL-interacting protein","NP_001138466.1//uncharacterized protein C2orf72 [Homo sapiens]","1//3"]
[177,1439,2.79,2.13,-0.389411691603349,0.333971328552126,"*",0.201148,"AGER","GO:0098794//postsynapse;GO:0016324//apical plasma membrane;GO:0030054//cell junction;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0001650//fibrillar center;GO:0005886//plasma membrane","GO:0038023//signaling receptor activity;GO:0001540//amyloid-beta binding;GO:0050785//advanced glycation end-product receptor activity;GO:1904599//advanced glycation end-product binding;GO:0004872//receptor activity;GO:0042802//identical protein binding;GO:0044548//S100 protein binding;GO:0005044//scavenger receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0008201//heparin binding","GO:0046330//positive regulation of JNK cascade;GO:0050930//induction of positive chemotaxis;GO:1904604//negative regulation of advanced glycation end-product receptor activity;GO:0007166//cell surface receptor signaling pathway;GO:0014002//astrocyte development;GO:1904645//response to amyloid-beta;GO:0051101//regulation of DNA binding;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:1900453//negative regulation of long term synaptic depression;GO:0045087//innate immune response;GO:0042104//positive regulation of activated T cell proliferation;GO:0009611//response to wounding;GO:0001914//regulation of T cell mediated cytotoxicity;GO:0001666//response to hypoxia;GO:2000514//regulation of CD4-positive, alpha-beta T cell activation;GO:1904597//negative regulation of connective tissue replacement involved in inflammatory response wound healing;GO:0048167//regulation of synaptic plasticity;GO:0010255//glucose mediated signaling pathway;GO:1900744//regulation of p38MAPK cascade;GO:0032693//negative regulation of interleukin-10 production;GO:0072657//protein localization to membrane;GO:1901222//regulation of NIK/NF-kappaB signaling;GO:0071639//positive regulation of monocyte chemotactic protein-1 production;GO:0032735//positive regulation of interleukin-12 production;GO:0090647//modulation of age-related behavioral decline;GO:1900272//negative regulation of long-term synaptic potentiation;GO:0031175//neuron projection development;GO:0001934//positive regulation of protein phosphorylation;GO:0007611//learning or memory;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:1903980//positive regulation of microglial cell activation;GO:0043507//positive regulation of JUN kinase activity;GO:0061890//positive regulation of astrocyte activation;GO:0006954//inflammatory response;GO:0042346//positive regulation of NF-kappaB import into nucleus;GO:1900745//positive regulation of p38MAPK cascade;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:2001200//positive regulation of dendritic cell differentiation","K19722//receptor for advanced glycosylation end products","XP_008953385.1//PREDICTED: advanced glycosylation end product-specific receptor isoform X4 [Pan paniscus];XP_003829814.1//PREDICTED: advanced glycosylation end product-specific receptor isoform X1 [Pan paniscus];XP_004043792.1//PREDICTED: advanced glycosylation end product-specific receptor isoform X3 [Gorilla gorilla gorilla];BAG60385.1//unnamed protein product [Homo sapiens];XP_009449255.1//PREDICTED: advanced glycosylation end product-specific receptor isoform X8 [Pan troglodytes];XP_008953386.1//PREDICTED: advanced glycosylation end product-specific receptor isoform X6 [Pan paniscus]","4;1//3;2//1"]
[51776,5604,19.28,14.73,-0.388347621194112,{"v":1.46080045824095e-12,"d":"1.46E-12"},"*",{"v":1.2373e-13,"d":"1.24E-13"},"MAP3K20","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0000287//magnesium ion binding;GO:0003723//RNA binding;GO:0004709//MAP kinase kinase kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding","GO:0006950//response to stress;GO:0035556//intracellular signal transduction;GO:0007050//cell cycle arrest;GO:0042733//embryonic digit morphogenesis;GO:0043065//positive regulation of apoptotic process;GO:0008283//cell proliferation;GO:0000186//activation of MAPKK activity;GO:0030154//cell differentiation;GO:0000077//DNA damage checkpoint;GO:0006468//protein phosphorylation;GO:0008219//cell death;GO:0007257//activation of JUN kinase activity;GO:0000075//cell cycle checkpoint;GO:0060173//limb development;GO:0009314//response to radiation;GO:0007010//cytoskeleton organization","K04424//sterile alpha motif and leucine zipper containing kinase AZK [EC:2.7.11.25]","BAD92211.1//Plaucible mixed-lineage kinase protein variant, partial [Homo sapiens];XP_011801357.1//PREDICTED: mitogen-activated protein kinase kinase kinase MLT isoform X2 [Colobus angolensis palliatus]","2//1"]
[3915,7889,25.11,19.2,-0.387155717662981,{"v":1.70190087741936E-17,"d":"1.70E-17"},"*",{"v":9.9084e-19,"d":"9.91E-19"},"LAMC1","GO:0043260//laminin-11 complex;GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0005606//laminin-1 complex;GO:0043259//laminin-10 complex;GO:0005576//extracellular region;GO:0005604//basement membrane","GO:0005201//extracellular matrix structural constituent","GO:0043687//post-translational protein modification;GO:0007492//endoderm development;GO:0016477//cell migration;GO:0034446//substrate adhesion-dependent cell spreading;GO:0031581//hemidesmosome assembly;GO:0044267//cellular protein metabolic process;GO:0022617//extracellular matrix disassembly;GO:0007155//cell adhesion;GO:0030198//extracellular matrix organization;GO:0006461//protein complex assembly;GO:0050679//positive regulation of epithelial cell proliferation","K05635//laminin, gamma 1","NP_002284.3//laminin subunit gamma-1 precursor [Homo sapiens]","3//A2MP1"]
[113791,2399,0.17,0.13,-0.387023123109247,0.833573204995515,"*",0.75629,"PIK3IP1","GO:0070062//extracellular exosome;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0016301//kinase activity;GO:0036313//phosphatidylinositol 3-kinase catalytic subunit binding","GO:0014067//negative regulation of phosphatidylinositol 3-kinase signaling;GO:0043553//negative regulation of phosphatidylinositol 3-kinase activity","K01343//tissue plasminogen activator [EC:3.4.21.68];K13912//deleted in malignant brain tumors 1 protein","NP_001129383.1//phosphoinositide-3-kinase-interacting protein 1 isoform 2 precursor [Homo sapiens];NP_443112.2//phosphoinositide-3-kinase-interacting protein 1 isoform 1 precursor [Homo sapiens]","1//3;4"]
[272,4168,2.34,1.79,-0.386548942319148,0.0473992448398152,"*",0.01991338,"AMPD3","NA","GO:0046872//metal ion binding;GO:0003876//AMP deaminase activity","GO:0046034//ATP metabolic process;GO:0034101//erythrocyte homeostasis;GO:0032264//IMP salvage;GO:0046031//ADP metabolic process;GO:0046033//AMP metabolic process;GO:0046039//GTP metabolic process;GO:0097009//energy homeostasis","K01490//AMP deaminase [EC:3.5.4.6]","XP_017200847.1//PREDICTED: LOW QUALITY PROTEIN: AMP deaminase 3 [Oryctolagus cuniculus];XP_011994561.1//PREDICTED: AMP deaminase 3 isoform X5 [Ovis aries musimon]","1//3;2//1"]
[7637,7056,1.79,1.37,-0.38578369430373,0.0651788505287225,"*",0.028554,"ZNF84","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0003676//nucleic acid binding","GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0001822//kidney development;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0048745//smooth muscle tissue development;GO:0014909//smooth muscle cell migration;GO:0035264//multicellular organism growth;GO:0006807//nitrogen compound metabolic process;GO:0009791//post-embryonic development;GO:0060325//face morphogenesis;GO:0060021//palate development;GO:0001570//vasculogenesis;GO:0030097//hemopoiesis;GO:0048705//skeletal system morphogenesis","K09228//KRAB domain-containing zinc finger protein","NP_001127531.1//zinc finger protein 84 [Pongo abelii]","1//3;2//1;5"]
[4199,3519,30.56,23.4,-0.385136013564982,{"v":1.03272750736842e-09,"d":"1.03E-09"},"*",{"v":1.166942e-10,"d":"1.17E-10"},"ME1","NA","NA","NA","K00029//malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40]","XP_017738116.1//PREDICTED: LOW QUALITY PROTEIN: NADP-dependent malic enzyme [Rhinopithecus bieti]",5]
[146909,4257,43.32,33.19,-0.384284613530027,{"v":9.03474298767773e-16,"d":"9.03E-16"},"*",{"v":5.96698e-17,"d":"5.97E-17"},"KIF18B","GO:0005634//nucleus;GO:0035371//microtubule plus-end;GO:0005737//cytoplasm;GO:1990752//microtubule end;GO:0000235//astral microtubule;GO:0005829//cytosol;GO:0016604//nuclear body;GO:0005871//kinesin complex","GO:0005524//ATP binding;GO:0003774//motor activity;GO:0003777//microtubule motor activity;GO:0019894//kinesin binding;GO:0008017//microtubule binding;GO:0016887//ATPase activity","GO:0000070//mitotic sister chromatid segregation;GO:0000278//mitotic cell cycle;GO:0007018//microtubule-based movement;GO:0051302//regulation of cell division;GO:0051301//cell division;GO:0007019//microtubule depolymerization","K10401//kinesin family member 18/19","XP_011522690.1//PREDICTED: kinesin-like protein KIF18B isoform X4 [Homo sapiens];ADE43428.1//KIF18B [Homo sapiens]","1//3"]
[285349,5948,0.9,0.69,-0.383328639551506,0.297463133083592,"*",0.1739826,"ZNF660","NA","NA","NA","K09229//KRAB and SCAN domains-containing zinc finger protein","XP_012789520.1//PREDICTED: zinc finger protein 197 isoform X2 [Sorex araneus]","3//A2MP1"]
[4238,4732,6.05,4.64,-0.382810337034385,1.21568290605061E-3,"*",0.000345892,"MFAP3","GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K17985//activating molecule in BECN1-regulated autophagy protein 1;K04006//decay accelerating factor","XP_018883219.1//PREDICTED: microfibril-associated glycoprotein 3 isoform X1 [Gorilla gorilla gorilla]","1//3;4"]
[1399,5336,10.36,7.95,-0.381997237514836,{"v":2.27051732484076e-05,"d":"2.27E-05"},"*",{"v":4.6863e-06,"d":"4.69E-06"},"CRKL","GO:0070062//extracellular exosome;GO:0005768//endosome;GO:0005829//cytosol","GO:0005070//SH3/SH2 adaptor activity;GO:0003723//RNA binding;GO:0001784//phosphotyrosine residue binding;GO:0042802//identical protein binding;GO:0004871//signal transducer activity;GO:0045296//cadherin binding","GO:0009952//anterior/posterior pattern specification;GO:0060017//parathyroid gland development;GO:0007507//heart development;GO:0048538//thymus development;GO:0035556//intracellular signal transduction;GO:0001568//blood vessel development;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:0007254//JNK cascade;GO:0009887//animal organ morphogenesis;GO:0007265//Ras protein signal transduction;GO:0008284//positive regulation of cell proliferation;GO:0000186//activation of MAPKK activity","K04438//proto-oncogene C-crk","XP_006140254.2//PREDICTED: crk-like protein [Tupaia chinensis]","3//A2MP1"]
[22877,8439,11.14,8.55,-0.381752907566772,{"v":1.56674034949592E-8,"d":"1.57E-08"},"*",{"v":2.04302e-09,"d":"2.04E-09"},"MLXIP","GO:0005634//nucleus;GO:0005741//mitochondrial outer membrane","GO:0000989//transcription factor activity, transcription factor binding;GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0046983//protein dimerization activity","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:1900402//regulation of carbohydrate metabolic process by regulation of transcription from RNA polymerase II promoter;GO:0045944//positive regulation of transcription from RNA polymerase II promoter","K09113//MAX-like protein X","NP_055753.3//MLX-interacting protein [Homo sapiens]",5]
[319,1720,0.56,0.43,-0.381090167355506,0.765507690140845,"*",0.666884,"APOF","GO:0034364//high-density lipoprotein particle;GO:0034362//low-density lipoprotein particle;GO:0005576//extracellular region","GO:0005319//lipid transporter activity;GO:0015485//cholesterol binding;GO:0005102//receptor binding","GO:0008203//cholesterol metabolic process;GO:0006869//lipid transport;GO:0006629//lipid metabolic process","K01368//cathepsin S [EC:3.4.22.27];K17985//activating molecule in BECN1-regulated autophagy protein 1;K00731//glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase [EC:2.4.1.122];K03155//timeless","XP_009246176.1//PREDICTED: apolipoprotein F isoform X1 [Pongo abelii]","2//1"]
[100131211,3637,1.9,1.46,-0.380031049450931,0.205642136345639,"*",0.1105452,"NEMP2","GO:0005635//nuclear envelope;GO:0016021//integral component of membrane","NA","NA","NA","BAH12468.1//unnamed protein product [Homo sapiens]","1//3"]
[8799,1642,15.73,12.09,-0.379704426166563,6.10735925461114E-3,"*",0.00201068,"PEX11B","GO:0016020//membrane;GO:0005779//integral component of peroxisomal membrane;GO:0070062//extracellular exosome;GO:0043234//protein complex;GO:0005777//peroxisome;GO:0005778//peroxisomal membrane","GO:0042803//protein homodimerization activity","GO:0007031//peroxisome organization;GO:0007165//signal transduction;GO:0044375//regulation of peroxisome size;GO:0051260//protein homooligomerization;GO:0016559//peroxisome fission","K13352//peroxin-11B","NP_001171724.1//peroxisomal membrane protein 11B isoform 2 [Homo sapiens];NP_003837.1//peroxisomal membrane protein 11B isoform 1 [Homo sapiens]","1//3;2//1"]
[84168,4836,39.95,30.72,-0.379017287094183,{"v":8.38482866666667e-31,"d":"8.38E-31"},"*",{"v":2.2046e-32,"d":"2.20E-32"},"ANTXR1","GO:0070062//extracellular exosome;GO:0010008//endosome membrane;GO:0009897//external side of plasma membrane;GO:0031258//lamellipodium membrane;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0031527//filopodium membrane;GO:0005886//plasma membrane","GO:0051015//actin filament binding;GO:0046872//metal ion binding;GO:0005518//collagen binding;GO:0004872//receptor activity;GO:0004888//transmembrane signaling receptor activity","GO:1901202//negative regulation of extracellular matrix assembly;GO:1905050//positive regulation of metallopeptidase activity;GO:0031532//actin cytoskeleton reorganization;GO:0034446//substrate adhesion-dependent cell spreading;GO:0022414//reproductive process;GO:0001568//blood vessel development","K20909//anthrax toxin receptor","XP_011800651.1//PREDICTED: anthrax toxin receptor 1 isoform X2 [Colobus angolensis palliatus];NP_060623.2//anthrax toxin receptor 1 isoform 3 precursor [Homo sapiens];NP_115584.1//anthrax toxin receptor 1 isoform 1 precursor [Homo sapiens]","3//A2MP1;2//1"]
[254251,5587,3.38,2.6,-0.37851162325373,0.0266961069222097,"*",0.01037662,"LCORL","GO:0005634//nucleus","GO:0003677//DNA binding","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter","K20015//ecdysone-induced protein 93F, isoform B;K06678//condensin complex subunit 3","NP_710153.2//ligand-dependent nuclear receptor corepressor-like protein isoform 2 [Homo sapiens];NP_001159611.1//ligand-dependent nuclear receptor corepressor-like protein isoform 1 [Homo sapiens]","8;2//1"]
[64800,4933,0.13,0.1,-0.37851162325373,0.723335547999109,"*",0.609904,"EFCAB6","GO:0005654//nucleoplasm","GO:0005509//calcium ion binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K02183//calmodulin","XP_016884400.1//PREDICTED: EF-hand calcium-binding domain-containing protein 6 isoform X4 [Homo sapiens]","3//A2MP1;2//1"]
[6519,2353,2.52,1.94,-0.377367081312789,0.250428690261177,"*",0.1416598,"SLC3A1","GO:0005774//vacuolar membrane;GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005887//integral component of plasma membrane;GO:0031526//brush border membrane;GO:0005743//mitochondrial inner membrane;GO:0005886//plasma membrane","GO:0015174//basic amino acid transmembrane transporter activity;GO:0046982//protein heterodimerization activity;GO:0003824//catalytic activity;GO:0015184//L-cystine transmembrane transporter activity;GO:0015171//amino acid transmembrane transporter activity","GO:0015802//basic amino acid transport;GO:0006865//amino acid transport;GO:0006520//cellular amino acid metabolic process;GO:0005975//carbohydrate metabolic process;GO:0015811//L-cystine transport","K14210//solute carrier family 3 (neutral and basic amino acid transporter), member 1","NP_000332.2//neutral and basic amino acid transport protein rBAT [Homo sapiens]","3//A2MP1"]
[29090,1562,16.25,12.52,-0.376205155870561,0.00727397328838951,"*",0.00243164,"TIMM21","GO:0005744//mitochondrial inner membrane presequence translocase complex;GO:0016021//integral component of membrane","NA","GO:0033617//mitochondrial respiratory chain complex IV assembly;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0030150//protein import into mitochondrial matrix","K17796//mitochondrial import inner membrane translocase subunit TIM21","NP_054896.2//mitochondrial import inner membrane translocase subunit Tim21 precursor [Homo sapiens]","2//1"]
[6294,3119,20.39,15.71,-0.3761785947224,{"v":7.47586887726048e-07,"d":"7.48E-07"},"*",{"v":1.216338E-7,"d":"1.22E-07"},"SAFB","GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0003723//RNA binding;GO:0003682//chromatin binding;GO:0043565//sequence-specific DNA binding;GO:0003690//double-stranded DNA binding;GO:0001047//core promoter binding","GO:0030520//intracellular estrogen receptor signaling pathway;GO:0042445//hormone metabolic process;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0050684//regulation of mRNA processing;GO:0006325//chromatin organization;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0040007//growth","K00753//glycoprotein 3-alpha-L-fucosyltransferase [EC:2.4.1.214];K12875//apoptotic chromatin condensation inducer in the nucleus;K18626//trichohyalin;K20780//mediator of DNA damage checkpoint protein 1","NP_002958.2//scaffold attachment factor B1 isoform 3 [Homo sapiens];NP_001188268.1//scaffold attachment factor B1 isoform 2 [Homo sapiens];NP_001188269.1//scaffold attachment factor B1 isoform 4 [Homo sapiens];NP_001188267.1//scaffold attachment factor B1 isoform 1 [Homo sapiens];NP_001307501.1//scaffold attachment factor B1 isoform 6 [Homo sapiens];NP_001307500.1//scaffold attachment factor B1 isoform 5 [Homo sapiens]","1//3;3//A2MP1"]
[54716,5344,0.96,0.74,-0.375509135092206,0.244958318711827,"*",0.13809,"SLC6A20","GO:0005887//integral component of plasma membrane;GO:0016324//apical plasma membrane;GO:0005886//plasma membrane","GO:0005328//neurotransmitter:sodium symporter activity;GO:0015171//amino acid transmembrane transporter activity","GO:0006865//amino acid transport;GO:0015816//glycine transport;GO:0015824//proline transport","K05048//solute carrier family 6 (neurotransmitter transporter, amino acid/orphan) member 15/16/17/18/20","AAL75944.1//neurotransmitter transporter RB21A [Homo sapiens]","3//A2MP1"]
[29945,2701,4.9,3.78,-0.374395514781498,0.0639092716229767,"*",0.0279298,"ANAPC4","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005680//anaphase-promoting complex","GO:0019903//protein phosphatase binding;GO:0004842//ubiquitin-protein transferase activity","GO:0070979//protein K11-linked ubiquitination;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0051301//cell division;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0030071//regulation of mitotic metaphase/anaphase transition;GO:0007049//cell cycle","K03351//anaphase-promoting complex subunit 4","NP_001273685.1//anaphase-promoting complex subunit 4 isoform 1 [Homo sapiens];NP_001125674.1//anaphase-promoting complex subunit 4 [Pongo abelii]","1//3;2//1"]
[8826,7219,29.93,23.1,-0.373699427194681,{"v":8.69112545695364e-18,"d":"8.69E-18"},"*",{"v":4.92936e-19,"d":"4.93E-19"},"IQGAP1","GO:0031252//cell leading edge;GO:0005874//microtubule;GO:0036057//slit diaphragm;GO:0005737//cytoplasm;GO:0030496//midbody;GO:0030426//growth cone;GO:0005911//cell-cell junction;GO:0005829//cytosol;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0015629//actin cytoskeleton;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0016328//lateral plasma membrane;GO:0005886//plasma membrane;GO:0030424//axon;GO:0070062//extracellular exosome;GO:0030667//secretory granule membrane;GO:0005634//nucleus;GO:0005925//focal adhesion;GO:0015630//microtubule cytoskeleton;GO:0043005//neuron projection;GO:0001726//ruffle;GO:0005884//actin filament;GO:0045121//membrane raft;GO:0030529//intracellular ribonucleoprotein complex;GO:0043234//protein complex","GO:0048365//Rac GTPase binding;GO:0043539//protein serine/threonine kinase activator activity;GO:0019903//protein phosphatase binding;GO:0019901//protein kinase binding;GO:0045296//cadherin binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0044548//S100 protein binding;GO:0019904//protein domain specific binding;GO:0051019//mitogen-activated protein kinase binding;GO:0005509//calcium ion binding;GO:0005095//GTPase inhibitor activity;GO:0005516//calmodulin binding;GO:0005096//GTPase activator activity;GO:0032403//protein complex binding","GO:1900086//positive regulation of peptidyl-tyrosine autophosphorylation;GO:0035305//negative regulation of dephosphorylation;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:1903829//positive regulation of cellular protein localization;GO:0071277//cellular response to calcium ion;GO:1990138//neuron projection extension;GO:1990776//response to angiotensin;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0045860//positive regulation of protein kinase activity;GO:0043312//neutrophil degranulation;GO:0036120//cellular response to platelet-derived growth factor stimulus;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:1904754//positive regulation of vascular associated smooth muscle cell migration;GO:1900006//positive regulation of dendrite development;GO:0007165//signal transduction;GO:0051894//positive regulation of focal adhesion assembly;GO:0043406//positive regulation of MAP kinase activity;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0043087//regulation of GTPase activity;GO:0001817//regulation of cytokine production;GO:0072015//glomerular visceral epithelial cell development","K16848//Ras GTPase-activating-like protein IQGAP1","XP_003901440.1//ras GTPase-activating-like protein IQGAP1 isoform X1 [Papio anubis]","3//A2MP1"]
[5256,5325,7.69,5.94,-0.372520667161061,0.00042290760057943,"*",1.096584E-4,"PHKA2","NA","GO:0016301//kinase activity;GO:0005516//calmodulin binding","GO:0005977//glycogen metabolic process","K07190//phosphorylase kinase alpha/beta subunit","XP_008063658.1//phosphorylase b kinase regulatory subunit alpha, liver isoform isoform X1 [Carlito syrichta]","2//1"]
[5198,5400,22.62,17.48,-0.371893744489222,{"v":2.54592905439331e-10,"d":"2.55E-10"},"*",{"v":2.66642e-11,"d":"2.67E-11"},"PFAS","NA","NA","NA","K01952//phosphoribosylformylglycinamidine synthase [EC:6.3.5.3]","XP_018869183.1//PREDICTED: phosphoribosylformylglycinamidine synthase isoform X1 [Gorilla gorilla gorilla]","2//1"]
[84890,3739,12.84,9.93,-0.370779579593929,0.000137833885231176,"*",{"v":3.26594e-05,"d":"3.27E-05"},"ADO","GO:0005829//cytosol;GO:0005739//mitochondrion","GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0046872//metal ion binding;GO:0047800//cysteamine dioxygenase activity","GO:0000098//sulfur amino acid catabolic process;GO:0055114//oxidation-reduction process","K10712//cysteamine dioxygenase [EC:1.13.11.19]","NP_116193.2//2-aminoethanethiol dioxygenase [Homo sapiens]",5]
[1277,5927,7.38,5.71,-0.370130070697553,0.000298443128340383,"*",{"v":7.50872e-05,"d":"7.51E-05"},"COL1A1","GO:0031012//extracellular matrix;GO:0005788//endoplasmic reticulum lumen;GO:0005584//collagen type I trimer;GO:0030141//secretory granule;GO:0005615//extracellular space;GO:0005794//Golgi apparatus;GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0002020//protease binding;GO:0048407//platelet-derived growth factor binding;GO:0046872//metal ion binding;GO:0005201//extracellular matrix structural constituent;GO:0042802//identical protein binding","GO:0043589//skin morphogenesis;GO:0001649//osteoblast differentiation;GO:0030335//positive regulation of cell migration;GO:0071260//cellular response to mechanical stimulus;GO:0007596//blood coagulation;GO:0030199//collagen fibril organization;GO:0007601//visual perception;GO:0071356//cellular response to tumor necrosis factor;GO:0001568//blood vessel development;GO:0071306//cellular response to vitamin E;GO:0032964//collagen biosynthetic process;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0032355//response to estradiol;GO:0015031//protein transport;GO:0042493//response to drug;GO:0044691//tooth eruption;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0031960//response to corticosteroid;GO:0071300//cellular response to retinoic acid;GO:0030198//extracellular matrix organization;GO:0055093//response to hyperoxia;GO:0048706//embryonic skeletal system development;GO:0030574//collagen catabolic process;GO:0030168//platelet activation;GO:0045893//positive regulation of transcription, DNA-templated;GO:1902618//cellular response to fluoride;GO:0060351//cartilage development involved in endochondral bone morphogenesis;GO:0060346//bone trabecula formation;GO:0070208//protein heterotrimerization;GO:0050776//regulation of immune response;GO:0034505//tooth mineralization;GO:0001958//endochondral ossification;GO:0050900//leukocyte migration;GO:0043434//response to peptide hormone;GO:0051591//response to cAMP;GO:0001957//intramembranous ossification;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0042542//response to hydrogen peroxide;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0071230//cellular response to amino acid stimulus;GO:0038063//collagen-activated tyrosine kinase receptor signaling pathway;GO:0007605//sensory perception of sound;GO:0010812//negative regulation of cell-substrate adhesion;GO:0060325//face morphogenesis;GO:0034504//protein localization to nucleus;GO:0001501//skeletal system development","K06236//collagen, type I, alpha","BAD92834.1//Collagen alpha 1 chain precursor variant, partial [Homo sapiens]","3//A2MP1"]
[10939,3223,19.32,14.95,-0.369949609750306,{"v":1.21510353076187E-5,"d":"1.22E-05"},"*",{"v":2.38624E-6,"d":"2.39E-06"},"AFG3L2","GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0005745//m-AAA complex","GO:0008237//metallopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0005524//ATP binding;GO:0051082//unfolded protein binding;GO:0008270//zinc ion binding","GO:0007528//neuromuscular junction development;GO:0042552//myelination;GO:0006851//mitochondrial calcium ion transmembrane transport;GO:0016540//protein autoprocessing;GO:0042407//cristae formation;GO:0036444//mitochondrial calcium uptake;GO:0040014//regulation of multicellular organism growth;GO:0048747//muscle fiber development;GO:0007409//axonogenesis;GO:0021675//nerve development;GO:0051560//mitochondrial calcium ion homeostasis;GO:0008053//mitochondrial fusion;GO:0006508//proteolysis;GO:0016485//protein processing;GO:0060013//righting reflex;GO:0034982//mitochondrial protein processing","K08956//AFG3 family protein [EC:3.4.24.-]","NP_006787.2//AFG3-like protein 2 [Homo sapiens]","2//1"]
[57473,5938,12.14,9.4,-0.369035759690682,{"v":2.11614790954774e-06,"d":"2.12E-06"},"*",{"v":3.69074e-07,"d":"3.69E-07"},"ZNF512B","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K11728//nucleosome-remodeling factor subunit BPTF;K00876//uridine kinase [EC:2.7.1.48]","XP_005260283.1//PREDICTED: zinc finger protein 512B isoform X1 [Homo sapiens]","2//1"]
[55331,7338,11.58,8.97,-0.368455363069975,{"v":1.54446109137272e-07,"d":"1.54E-07"},"*",{"v":2.27502e-08,"d":"2.28E-08"},"ACER3","GO:0030173//integral component of Golgi membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0070774//phytoceramidase activity","GO:0046512//sphingosine biosynthetic process;GO:0030148//sphingolipid biosynthetic process;GO:0071602//phytosphingosine biosynthetic process;GO:0008284//positive regulation of cell proliferation;GO:0006672//ceramide metabolic process","K04711//dihydroceramidase [EC:3.5.1.-]","NP_001287882.1//alkaline ceramidase 3 isoform b [Homo sapiens];NP_060837.3//alkaline ceramidase 3 isoform a [Homo sapiens]","6;1//3"]
[64172,2047,4.44,3.44,-0.368151111648008,0.154904743396226,"*",0.0791494,"OSGEPL1","GO:0000408//EKC/KEOPS complex;GO:0005739//mitochondrion","GO:0046872//metal ion binding;GO:0004222//metalloendopeptidase activity;GO:0061711//N(6)-L-threonylcarbamoyladenine synthase","GO:0002949//tRNA threonylcarbamoyladenosine modification","K01409//N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]","NP_001341276.1//probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial isoform 2 [Homo sapiens]","1//3;2//1"]
[11231,6500,7.07,5.48,-0.367534321848872,0.000210975216666667,"*",{"v":5.16674e-05,"d":"5.17E-05"},"SEC63","GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005622//intracellular;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0003723//RNA binding;GO:0004872//receptor activity;GO:0008565//protein transporter activity","GO:0010259//multicellular organism aging;GO:0006612//protein targeting to membrane;GO:0001889//liver development;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006807//nitrogen compound metabolic process;GO:0036498//IRE1-mediated unfolded protein response;GO:0072001//renal system development;GO:0006620//posttranslational protein targeting to endoplasmic reticulum membrane;GO:0031204//posttranslational protein targeting to membrane, translocation","K09540//translocation protein SEC63","NP_009145.1//translocation protein SEC63 homolog [Homo sapiens]",4]
[5318,4439,0.98,0.76,-0.366782330671623,0.365874052173913,"*",0.226524,"PKP2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0001533//cornified envelope;GO:0030054//cell junction;GO:0005882//intermediate filament;GO:0005912//adherens junction;GO:0005911//cell-cell junction;GO:0016021//integral component of membrane;GO:0014704//intercalated disc;GO:0005886//plasma membrane;GO:0030057//desmosome","GO:0005080//protein kinase C binding;GO:0032947//protein complex scaffold activity;GO:0044325//ion channel binding;GO:0086083//cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication;GO:0017080//sodium channel regulator activity;GO:0045294//alpha-catenin binding;GO:0019215//intermediate filament binding;GO:0045296//cadherin binding","GO:0098911//regulation of ventricular cardiac muscle cell action potential;GO:2000810//regulation of bicellular tight junction assembly;GO:0031424//keratinization;GO:0070268//cornification;GO:0098609//cell-cell adhesion;GO:0016264//gap junction assembly;GO:0002159//desmosome assembly;GO:0086064//cell communication by electrical coupling involved in cardiac conduction;GO:0008285//negative regulation of cell proliferation;GO:0086019//cell-cell signaling involved in cardiac conduction;GO:0086005//ventricular cardiac muscle cell action potential;GO:0045110//intermediate filament bundle assembly;GO:0086073//bundle of His cell-Purkinje myocyte adhesion involved in cell communication;GO:0072659//protein localization to plasma membrane;GO:0086001//cardiac muscle cell action potential;GO:0007507//heart development;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0086091//regulation of heart rate by cardiac conduction;GO:0030336//negative regulation of cell migration;GO:0010765//positive regulation of sodium ion transport;GO:0086002//cardiac muscle cell action potential involved in contraction;GO:0048496//maintenance of animal organ identity;GO:0034334//adherens junction maintenance;GO:0055088//lipid homeostasis","K12642//plakophilin 2","NP_001005242.2//plakophilin-2 isoform 2a [Homo sapiens];NP_004563.2//plakophilin-2 isoform 2b [Homo sapiens]","3//A2MP1;2//1"]
[51768,4346,24.13,18.72,-0.366247480632347,{"v":9.21091379692917e-09,"d":"9.21E-09"},"*",{"v":1.164194e-09,"d":"1.16E-09"},"TM7SF3","GO:0070062//extracellular exosome;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","NA","GO:0032024//positive regulation of insulin secretion;GO:0043069//negative regulation of programmed cell death;GO:0034620//cellular response to unfolded protein","K12581//CCR4-NOT transcription complex subunit 7/8;K12025//tripartite motif-containing protein 52","XP_004052943.2//PREDICTED: transmembrane 7 superfamily member 3 isoform X1 [Gorilla gorilla gorilla]","2//1"]
[9520,4364,36.99,28.73,-0.364577307591472,{"v":1.64932320450161e-13,"d":"1.65E-13"},"*",{"v":1.284436E-14,"d":"1.28E-14"},"NPEPPS","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0008237//metallopeptidase activity;GO:0004177//aminopeptidase activity;GO:0008270//zinc ion binding;GO:0042277//peptide binding;GO:0070006//metalloaminopeptidase activity","GO:0071456//cellular response to hypoxia;GO:0006508//proteolysis;GO:1903955//positive regulation of protein targeting to mitochondrion;GO:0043171//peptide catabolic process;GO:0000209//protein polyubiquitination","K08776//puromycin-sensitive aminopeptidase [EC:3.4.11.-]","XP_011901743.1//PREDICTED: puromycin-sensitive aminopeptidase isoform X1 [Cercocebus atys];NP_006301.3//puromycin-sensitive aminopeptidase isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[10772,7648,12.69,9.86,-0.364032517463194,{"v":3.41105240454915e-07,"d":"3.41E-07"},"*",{"v":5.2573e-08,"d":"5.26E-08"},"SRSF10","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0005737//cytoplasm","GO:0050733//RS domain binding;GO:0003723//RNA binding;GO:0051082//unfolded protein binding","GO:0043484//regulation of RNA splicing;GO:0006406//mRNA export from nucleus;GO:0000244//spliceosomal tri-snRNP complex assembly;GO:0006376//mRNA splice site selection;GO:0000398//mRNA splicing, via spliceosome;GO:0006355//regulation of transcription, DNA-templated;GO:0000375//RNA splicing, via transesterification reactions;GO:0016482//cytosolic transport;GO:0048025//negative regulation of mRNA splicing, via spliceosome;GO:0048024//regulation of mRNA splicing, via spliceosome","K12900//FUS-interacting serine-arginine-rich protein 1;K12891//splicing factor, arginine/serine-rich 2","BAE22485.1//unnamed protein product [Mus musculus];XP_019836877.1//PREDICTED: serine/arginine-rich splicing factor 10 isoform X1 [Bos indicus];XP_010624250.1//PREDICTED: serine/arginine-rich splicing factor 10 isoform X1 [Fukomys damarensis];NP_001177936.1//serine/arginine-rich splicing factor 10 isoform 5 [Homo sapiens];NP_006616.1//serine/arginine-rich splicing factor 10 isoform 1 [Homo sapiens];NP_001177938.1//serine/arginine-rich splicing factor 10 isoform 6 [Homo sapiens];XP_020949038.1//serine/arginine-rich splicing factor 10 isoform X3 [Sus scrofa];XP_020949037.1//serine/arginine-rich splicing factor 10 isoform X2 [Sus scrofa]","1//3;3//A2MP1;2//1;5"]
[9797,4909,17.57,13.66,-0.363156707718286,{"v":3.09397590883191e-07,"d":"3.09E-07"},"*",{"v":4.75892e-08,"d":"4.76E-08"},"TATDN2","GO:0005654//nucleoplasm","GO:0046872//metal ion binding;GO:0004536//deoxyribonuclease activity;GO:0016888//endodeoxyribonuclease activity, producing 5'-phosphomonoesters","GO:0036498//IRE1-mediated unfolded protein response;GO:0006308//DNA catabolic process","K03424//TatD DNase family protein [EC:3.1.21.-]","NP_055575.3//putative deoxyribonuclease TATDN2 [Homo sapiens]","3//A2MP1"]
[80129,5283,0.09,0.07,-0.362570079384708,0.833400693984547,"*",0.75629,"CCDC170","NA","NA","NA","K10352//myosin heavy chain","NP_079335.2//coiled-coil domain-containing protein 170 [Homo sapiens]","3//A2MP1"]
[10038,1865,16.3,12.68,-0.362317218979033,0.00408902237583893,"*",1.296794E-3,"PARP2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:1990404//protein ADP-ribosylase activity;GO:0003910//DNA ligase (ATP) activity;GO:0003950//NAD+ ADP-ribosyltransferase activity","GO:0006273//lagging strand elongation;GO:0097191//extrinsic apoptotic signaling pathway;GO:0006281//DNA repair;GO:0006284//base-excision repair;GO:0018312//peptidyl-serine ADP-ribosylation;GO:0051103//DNA ligation involved in DNA repair;GO:0006471//protein ADP-ribosylation","K10798//poly [ADP-ribose] polymerase [EC:2.4.2.30]","NP_005475.2//poly [ADP-ribose] polymerase 2 isoform 1 [Homo sapiens];NP_001036083.1//poly [ADP-ribose] polymerase 2 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[23168,5038,12.27,9.55,-0.361562610739794,{"v":1.9739944e-05,"d":"1.97E-05"},"*",{"v":4.02856e-06,"d":"4.03E-06"},"RTF1","NA","NA","NA","K15178//RNA polymerase-associated protein RTF1","XP_012621920.1//RNA polymerase-associated protein RTF1 homolog [Microcebus murinus]",4]
[92285,6210,1.49,1.16,-0.36118752533459,0.146761917361111,"*",0.0740884,"ZNF585B","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","NP_689492.3//zinc finger protein 585B [Homo sapiens]","3//A2MP1"]
[389114,5524,0.77,0.6,-0.359895945086383,0.407602568133769,"*",0.265526,"ZNF662","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","XP_015091703.1//PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein LOC102544301 [Vicugna pacos];XP_006195790.2//PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 850 [Camelus ferus]","1//3;3//A2MP1"]
[5610,4119,12.21,9.52,-0.35902972167946,0.00179220587428084,"*",0.000526532,"EIF2AK2","GO:0005840//ribosome;GO:0016020//membrane;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm","GO:0003723//RNA binding;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0004694//eukaryotic translation initiation factor 2alpha kinase activity;GO:0019888//protein phosphatase regulator activity;GO:0003725//double-stranded RNA binding;GO:0003743//translation initiation factor activity;GO:0004674//protein serine/threonine kinase activity;GO:0004672//protein kinase activity","GO:0034198//cellular response to amino acid starvation;GO:0001819//positive regulation of cytokine production;GO:0009636//response to toxic substance;GO:0017148//negative regulation of translation;GO:0045071//negative regulation of viral genome replication;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0045087//innate immune response;GO:0000186//activation of MAPKK activity;GO:0008285//negative regulation of cell proliferation;GO:1900225//regulation of NLRP3 inflammasome complex assembly;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0006468//protein phosphorylation;GO:0051607//defense response to virus;GO:0006351//transcription, DNA-templated;GO:0043066//negative regulation of apoptotic process;GO:0032874//positive regulation of stress-activated MAPK cascade;GO:0046777//protein autophosphorylation;GO:1902033//regulation of hematopoietic stem cell proliferation;GO:0033689//negative regulation of osteoblast proliferation;GO:0035455//response to interferon-alpha;GO:1901532//regulation of hematopoietic progenitor cell differentiation;GO:0010998//regulation of translational initiation by eIF2 alpha phosphorylation;GO:0006412//translation;GO:1902036//regulation of hematopoietic stem cell differentiation;GO:0030683//evasion or tolerance by virus of host immune response;GO:0042981//regulation of apoptotic process;GO:0009615//response to virus;GO:0032722//positive regulation of chemokine production","K16195//eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]","XP_014199275.1//PREDICTED: interferon-induced, double-stranded RNA-activated protein kinase isoform X1 [Pan paniscus];NP_001129124.1//interferon-induced, double-stranded RNA-activated protein kinase isoform b [Homo sapiens]","3//A2MP1;2//1"]
[153,2862,0.5,0.39,-0.358453970912476,0.64672015653897,"*",0.490364,"ADRB1","GO:0005887//integral component of plasma membrane;GO:0005622//intracellular;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005769//early endosome","GO:0005057//signal transducer activity, downstream of receptor;GO:0046982//protein heterodimerization activity;GO:0051379//epinephrine binding;GO:0051380//norepinephrine binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0031694//alpha-2A adrenergic receptor binding;GO:0004939//beta-adrenergic receptor activity;GO:0030165//PDZ domain binding;GO:0004940//beta1-adrenergic receptor activity","GO:0001659//temperature homeostasis;GO:0031649//heat generation;GO:0043547//positive regulation of GTPase activity;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0040015//negative regulation of multicellular organism growth;GO:0030819//positive regulation of cAMP biosynthetic process;GO:0043950//positive regulation of cAMP-mediated signaling;GO:0001996//positive regulation of heart rate by epinephrine-norepinephrine;GO:0002024//diet induced thermogenesis;GO:0009409//response to cold;GO:0007267//cell-cell signaling;GO:0045823//positive regulation of heart contraction;GO:0001997//positive regulation of the force of heart contraction by epinephrine-norepinephrine;GO:0071880//adenylate cyclase-activating adrenergic receptor signaling pathway;GO:0007190//activation of adenylate cyclase activity;GO:0050873//brown fat cell differentiation;GO:0002025//norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure;GO:0042596//fear response","K04141//adrenergic receptor beta-1","NP_000675.1//beta-1 adrenergic receptor [Homo sapiens]","2//1"]
[54901,3272,4.73,3.69,-0.358219367278999,0.0509925473187979,"*",0.0216688,"CDKAL1","GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0005791//rough endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0061712//tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase;GO:0046872//metal ion binding;GO:0035598//N6-threonylcarbomyladenosine methylthiotransferase activity;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0016740//transferase activity","GO:1990145//maintenance of translational fidelity;GO:0006400//tRNA modification","K15865//threonylcarbamoyladenosine tRNA methylthiotransferase CDKAL1 [EC:2.8.4.5]","NP_060244.2//threonylcarbamoyladenosine tRNA methylthiotransferase [Homo sapiens]","3//A2MP1"]
[9612,8764,59.8,46.69,-0.357031895843278,{"v":7.79570258683385e-38,"d":"7.80E-38"},"*",{"v":1.556798E-39,"d":"1.56E-39"},"NCOR2","GO:0016020//membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000785//chromatin;GO:0016363//nuclear matrix;GO:0000790//nuclear chromatin;GO:0017053//transcriptional repressor complex;GO:0016604//nuclear body;GO:0000118//histone deacetylase complex","GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0047485//protein N-terminus binding;GO:0042826//histone deacetylase binding;GO:0035259//glucocorticoid receptor binding;GO:0001012//RNA polymerase II regulatory region DNA binding;GO:0016922//ligand-dependent nuclear receptor binding;GO:0046965//retinoid X receptor binding;GO:0003682//chromatin binding;GO:0005112//Notch binding;GO:0008134//transcription factor binding;GO:0032403//protein complex binding","GO:0007595//lactation;GO:0010243//response to organonitrogen compound;GO:0006351//transcription, DNA-templated;GO:0044849//estrous cycle;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0032355//response to estradiol;GO:0019216//regulation of lipid metabolic process;GO:1903799//negative regulation of production of miRNAs involved in gene silencing by miRNA;GO:0072365//regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter","K06065//nuclear receptor co-repressor 2","NP_001193583.1//nuclear receptor corepressor 2 isoform 3 [Homo sapiens];NP_006303.4//nuclear receptor corepressor 2 isoform 1 [Homo sapiens];NP_001070729.2//nuclear receptor corepressor 2 isoform 2 [Homo sapiens]","1//3;3//A2MP1;5"]
[10308,3268,2.74,2.14,-0.35656509655938,0.157455825339035,"*",0.0806796,"ZNF267","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_012669229.1//PREDICTED: zinc finger protein 267 [Otolemur garnettii]","1//3;5"]
[25994,2785,26.05,20.36,-0.355545811090175,{"v":4.88359718378378e-06,"d":"4.88E-06"},"*",{"v":9.04936e-07,"d":"9.05E-07"},"HIGD1A","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0043234//protein complex;GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0070469//respiratory chain;GO:0005739//mitochondrion","NA","GO:0071456//cellular response to hypoxia;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0043066//negative regulation of apoptotic process;GO:0042149//cellular response to glucose starvation;GO:0055114//oxidation-reduction process;GO:0090201//negative regulation of release of cytochrome c from mitochondria","K12581//CCR4-NOT transcription complex subunit 7/8;K17985//activating molecule in BECN1-regulated autophagy protein 1","NP_001093138.1//HIG1 domain family member 1A, mitochondrial isoform a [Homo sapiens]","1//3;3//A2MP1"]
[101929372,1838,4.59,3.59,-0.354510309590757,0.205296322236459,"*",0.1103336,"LOC101929372","NA","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K15107//solute carrier family 25 (mitochondrial glutamate transporter), member 18/22","NP_001275636.1//uncharacterized protein LOC101929372 [Homo sapiens]","1//3"]
[1109,1192,0.23,0.18,-0.353636954614701,0.782707832243389,"*",0.689316,"AKR1C4","NA","NA","NA","K00037//3alpha-hydroxysteroid 3-dehydrogenase / chlordecone reductase [EC:1.1.1.50 1.1.1.357 1.1.1.225];K04119//aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]","XP_017716094.1//PREDICTED: aldo-keto reductase family 1 member C4 [Rhinopithecus bieti]","3//A2MP1"]
[8120,3982,0.6,0.47,-0.352301743930881,0.852857781151689,"*",0.780674,"AP3B2","GO:1904115//axon cytoplasm;GO:0030131//clathrin adaptor complex;GO:0030123//AP-3 adaptor complex","NA","GO:0006886//intracellular protein transport;GO:0048490//anterograde synaptic vesicle transport;GO:0016192//vesicle-mediated transport","K12397//AP-3 complex subunit beta","XP_021796519.1//AP-3 complex subunit beta-2 isoform X4 [Papio anubis];XP_011809281.1//PREDICTED: AP-3 complex subunit beta-2 isoform X3 [Colobus angolensis palliatus];XP_001082801.1//PREDICTED: AP-3 complex subunit beta-2 [Macaca mulatta];XP_011809278.1//PREDICTED: AP-3 complex subunit beta-2 isoform X1 [Colobus angolensis palliatus];XP_004056719.1//PREDICTED: AP-3 complex subunit beta-2 isoform X2 [Gorilla gorilla gorilla]","4;1//3"]
[91862,2428,3.14,2.46,-0.352106243552387,0.24933836408326,"*",0.1409806,"MARVELD3","GO:0031410//cytoplasmic vesicle;GO:0016021//integral component of membrane;GO:0005923//bicellular tight junction","GO:0031435//mitogen-activated protein kinase kinase kinase binding","GO:0045216//cell-cell junction organization;GO:1902414//protein localization to cell junction;GO:0070830//bicellular tight junction assembly;GO:0006970//response to osmotic stress;GO:0046329//negative regulation of JNK cascade;GO:0050680//negative regulation of epithelial cell proliferation;GO:0010633//negative regulation of epithelial cell migration","K21099//MARVEL domain-containing protein 3","XP_016785621.1//PREDICTED: MARVEL domain-containing protein 3 isoform X1 [Pan troglodytes];XP_016785622.1//PREDICTED: MARVEL domain-containing protein 3 isoform X2 [Pan troglodytes];NP_001017967.2//MARVEL domain-containing protein 3 isoform 1 [Homo sapiens]","1//3;3//A2MP1;5"]
[2151,3446,11.07,8.68,-0.350888274337073,0.000914488082995038,"*",0.00025384,"F2RL2","GO:0005887//integral component of plasma membrane;GO:0016324//apical plasma membrane;GO:0043234//protein complex;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0004435//phosphatidylinositol phospholipase C activity;GO:0015057//thrombin-activated receptor activity;GO:0004930//G-protein coupled receptor activity","GO:0009611//response to wounding;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway;GO:0035025//positive regulation of Rho protein signal transduction;GO:0007596//blood coagulation;GO:0030168//platelet activation","K04235//coagulation factor II (thrombin) receptor-like 2","NP_004092.1//proteinase-activated receptor 3 isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[89932,5849,2.09,1.64,-0.349807127462799,0.103448943637575,"*",0.048603,"PAPLN","GO:0005576//extracellular region","GO:0008233//peptidase activity;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding","NA","K08621//a disintegrin and metalloproteinase with thrombospondin motifs 6 [EC:3.4.24.-]","NP_775733.3//papilin precursor [Homo sapiens]","3//A2MP1"]
[51099,4062,3.58,2.81,-0.34938945704333,0.291994632241435,"*",0.1701992,"ABHD5","GO:0005811//lipid droplet;GO:0005829//cytosol","GO:0016787//hydrolase activity;GO:0003841//1-acylglycerol-3-phosphate O-acyltransferase activity;GO:0042171//lysophosphatidic acid acyltransferase activity","GO:0010891//negative regulation of sequestering of triglyceride;GO:0010898//positive regulation of triglyceride catabolic process;GO:0030154//cell differentiation;GO:0006631//fatty acid metabolic process;GO:0051006//positive regulation of lipoprotein lipase activity;GO:0006629//lipid metabolic process;GO:0006654//phosphatidic acid biosynthetic process","K13699//abhydrolase domain-containing protein 5 [EC:2.3.1.51]","NP_057090.2//1-acylglycerol-3-phosphate O-acyltransferase ABHD5 [Homo sapiens]","1//3;5"]
[23741,2096,36.88,28.96,-0.348777053346133,{"v":3.99156774982818e-06,"d":"3.99E-06"},"*",{"v":7.27148e-07,"d":"7.27E-07"},"EID1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0036464//cytoplasmic ribonucleoprotein granule","GO:0003714//transcription corepressor activity;GO:0035034//histone acetyltransferase regulator activity;GO:0035035//histone acetyltransferase binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0035065//regulation of histone acetylation;GO:0030154//cell differentiation;GO:0006351//transcription, DNA-templated;GO:0007049//cell cycle;GO:0045595//regulation of cell differentiation","K17449//SHC-transforming protein 4","NP_055150.1//EP300-interacting inhibitor of differentiation 1 [Homo sapiens]","2//1"]
[2799,5144,27.02,21.23,-0.347923303420307,{"v":2.53402511789348e-10,"d":"2.53E-10"},"*",{"v":2.65078e-11,"d":"2.65E-11"},"GNS","GO:0070062//extracellular exosome;GO:0035578//azurophil granule lumen;GO:0043202//lysosomal lumen;GO:1904813//ficolin-1-rich granule lumen;GO:0005576//extracellular region;GO:0005764//lysosome","GO:0046872//metal ion binding;GO:0008484//sulfuric ester hydrolase activity;GO:0008449//N-acetylglucosamine-6-sulfatase activity","GO:0042340//keratan sulfate catabolic process;GO:0043312//neutrophil degranulation;GO:0006027//glycosaminoglycan catabolic process;GO:0030203//glycosaminoglycan metabolic process","K01137//N-acetylglucosamine-6-sulfatase [EC:3.1.6.14]","NP_002067.1//N-acetylglucosamine-6-sulfatase precursor [Homo sapiens]","3//A2MP1"]
[130497,1911,10.43,8.2,-0.34704334301432,0.0314715974614173,"*",0.01251062,"OSR1","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","XP_020386293.1//zinc finger protein 208-like [Rhincodon typus]","2//1"]
[84445,2806,29.03,22.84,-0.345981921263819,{"v":2.06323358099352e-06,"d":"2.06E-06"},"*",{"v":3.58812e-07,"d":"3.59E-07"},"LZTS2","GO:0005815//microtubule organizing center;GO:0005874//microtubule;GO:0005829//cytosol;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0031982//vesicle;GO:0005886//plasma membrane;GO:0030496//midbody","NA","GO:0001822//kidney development;GO:0030178//negative regulation of Wnt signaling pathway;GO:0000910//cytokinesis;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0051168//nuclear export;GO:0051301//cell division;GO:1900181//negative regulation of protein localization to nucleus;GO:0016055//Wnt signaling pathway;GO:0051255//spindle midzone assembly;GO:0051013//microtubule severing;GO:0007049//cell cycle;GO:0008285//negative regulation of cell proliferation","K03006//DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6];K21882//PDZ domain-containing protein 7","NP_115805.1//leucine zipper putative tumor suppressor 2 isoform a [Homo sapiens];NP_001305030.1//leucine zipper putative tumor suppressor 2 isoform b [Homo sapiens]","1//3;3//A2MP1"]
[54888,3338,33.54,26.4,-0.345344759318531,{"v":9.95210131558185e-09,"d":"9.95E-09"},"*",{"v":1.263482e-09,"d":"1.26E-09"},"NSUN2","GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0033391//chromatoid body;GO:0005819//spindle;GO:0005737//cytoplasm","GO:0016428//tRNA (cytosine-5-)-methyltransferase activity;GO:0003723//RNA binding;GO:0000049//tRNA binding","GO:0048820//hair follicle maturation;GO:0051301//cell division;GO:0006400//tRNA modification;GO:0030488//tRNA methylation;GO:0033313//meiotic cell cycle checkpoint;GO:0007286//spermatid development","K15335//tRNA (cytosine34-C5)-methyltransferase [EC:2.1.1.203]","NP_060225.4//tRNA (cytosine(34)-C(5))-methyltransferase isoform 1 [Homo sapiens];NP_001180384.1//tRNA (cytosine(34)-C(5))-methyltransferase isoform 2 [Homo sapiens]","1//3;5"]
[56889,6140,31.76,25,-0.345282817593508,{"v":5.69972369942197e-14,"d":"5.70E-14"},"*",{"v":4.321e-15,"d":"4.32E-15"},"TM9SF3","GO:0016021//integral component of membrane","NA","NA","K17087//transmembrane 9 superfamily member 3","BAD90204.1//mKIAA4036 protein, partial [Mus musculus]","3//A2MP1"]
[420,5167,0.33,0.26,-0.343954401217361,0.578802215606986,"*",0.421148,"ART4","GO:0016020//membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0031225//anchored component of membrane","GO:0003956//NAD(P)+-protein-arginine ADP-ribosyltransferase activity","GO:0006525//arginine metabolic process;GO:0006501//C-terminal protein lipidation;GO:0006471//protein ADP-ribosylation","K06717//ADP-ribosyltransferase 4 [EC:2.4.2.31]","NP_066549.2//ecto-ADP-ribosyltransferase 4 isoform 1 precursor [Homo sapiens];NP_001341575.1//ecto-ADP-ribosyltransferase 4 isoform 2 precursor [Homo sapiens]","1//3;3//A2MP1"]
[23064,11163,3.35,2.64,-0.343623165986681,0.00178554654615221,"*",0.000524352,"SETX","GO:0030424//axon;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000781//chromosome, telomeric region;GO:0005737//cytoplasm;GO:0045171//intercellular bridge;GO:0000228//nuclear chromosome;GO:0030426//growth cone;GO:0005730//nucleolus;GO:0016604//nuclear body","GO:0003677//DNA binding;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0001147//transcription termination site sequence-specific DNA binding;GO:0003678//DNA helicase activity","GO:0006396//RNA processing;GO:0033120//positive regulation of RNA splicing;GO:0006376//mRNA splice site selection;GO:0006369//termination of RNA polymerase II transcription;GO:0043491//protein kinase B signaling;GO:0007283//spermatogenesis;GO:0006302//double-strand break repair;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0006974//cellular response to DNA damage stimulus;GO:0070301//cellular response to hydrogen peroxide;GO:2000806//positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled;GO:0007623//circadian rhythm;GO:0006353//DNA-templated transcription, termination;GO:0000165//MAPK cascade;GO:0043066//negative regulation of apoptotic process;GO:2000144//positive regulation of DNA-templated transcription, initiation;GO:0010976//positive regulation of neuron projection development;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0060566//positive regulation of DNA-templated transcription, termination;GO:0071300//cellular response to retinoic acid;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0034599//cellular response to oxidative stress;GO:0006310//DNA recombination","K10706//senataxin [EC:3.6.4.-]","NP_001338457.1//probable helicase senataxin isoform 2 [Homo sapiens];NP_055861.3//probable helicase senataxin isoform 1 [Homo sapiens]","6;1//3"]
[2054,3282,16.77,13.22,-0.343160512056654,{"v":6.35363721626929e-05,"d":"6.35E-05"},"*",{"v":1.417974E-5,"d":"1.42E-05"},"STX2","GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0016323//basolateral plasma membrane;GO:0005615//extracellular space;GO:0008021//synaptic vesicle;GO:0005622//intracellular;GO:0030027//lamellipodium;GO:0016021//integral component of membrane;GO:0031201//SNARE complex;GO:0005886//plasma membrane","GO:0000149//SNARE binding;GO:0005484//SNAP receptor activity;GO:0048306//calcium-dependent protein binding;GO:0046983//protein dimerization activity","GO:0031629//synaptic vesicle fusion to presynaptic active zone membrane;GO:0007165//signal transduction;GO:0030154//cell differentiation;GO:0033194//response to hydroperoxide;GO:1903575//cornified envelope assembly;GO:0016192//vesicle-mediated transport;GO:0007398//ectoderm development;GO:0006886//intracellular protein transport;GO:0030193//regulation of blood coagulation;GO:0007340//acrosome reaction;GO:0009887//animal organ morphogenesis;GO:0048278//vesicle docking;GO:0051259//protein oligomerization","K08486//syntaxin 1B/2/3","NP_001337980.1//syntaxin-2 isoform 5 [Homo sapiens];NP_001337978.1//syntaxin-2 isoform 3 [Homo sapiens];NP_001337979.1//syntaxin-2 isoform 4 [Homo sapiens];NP_001971.2//syntaxin-2 isoform 1 [Homo sapiens];NP_919337.1//syntaxin-2 isoform 2 [Homo sapiens]","4;1//3;3//A2MP1"]
[56667,2899,2.23,1.76,-0.341468281283007,0.281600332871073,"*",0.1627126,"MUC13","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0016324//apical plasma membrane;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005796//Golgi lumen","GO:0042803//protein homodimerization activity","GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0016266//O-glycan processing;GO:0030277//maintenance of gastrointestinal epithelium","K17298//mucin-13","NP_149038.3//mucin-13 precursor [Homo sapiens]","3//A2MP1"]
[84133,6575,6.93,5.47,-0.341314519344657,0.000612142793549895,"*",1.639764E-4,"ZNRF3","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0061630//ubiquitin protein ligase activity;GO:0046872//metal ion binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005109//frizzled binding","GO:0030178//negative regulation of Wnt signaling pathway;GO:0016567//protein ubiquitination;GO:2000051//negative regulation of non-canonical Wnt signaling pathway;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0060070//canonical Wnt signaling pathway;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0072089//stem cell proliferation;GO:0038018//Wnt receptor catabolic process","K16273//E3 ubiquitin-protein ligase ZNRF3 [EC:2.3.2.27]","NP_001193927.1//E3 ubiquitin-protein ligase ZNRF3 isoform 1 precursor [Homo sapiens];XP_011528737.1//PREDICTED: E3 ubiquitin-protein ligase ZNRF3 isoform X1 [Homo sapiens]","1//3;3//A2MP1"]
[26064,4967,21.56,17.02,-0.341126141066543,{"v":5.84862720214669e-08,"d":"5.85E-08"},"*",{"v":8.18676e-09,"d":"8.19E-09"},"RAI14","GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0005938//cell cortex;GO:0005829//cytosol;GO:0001650//fibrillar center;GO:0030054//cell junction;GO:0005739//mitochondrion","NA","GO:0030154//cell differentiation;GO:0007283//spermatogenesis","K15503//serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B;K21440//ankyrin repeat domain-containing protein 50","NP_001138994.1//ankycorbin isoform b [Homo sapiens];NP_056392.2//ankycorbin isoform a [Homo sapiens];NP_001138997.1//ankycorbin isoform d [Homo sapiens];NP_001138995.1//ankycorbin isoform c [Homo sapiens]","1//3;2//1"]
[285343,2236,6.14,4.85,-0.340253908295689,0.0792002371214226,"*",0.0356882,"TCAIM","GO:0005739//mitochondrion","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K09228//KRAB domain-containing zinc finger protein","NP_776187.2//T-cell activation inhibitor, mitochondrial isoform 1 [Homo sapiens];NP_001025011.1//T-cell activation inhibitor, mitochondrial isoform 2 [Homo sapiens];XP_011889429.1//PREDICTED: T-cell activation inhibitor, mitochondrial isoform X1 [Cercocebus atys]","1//3;3//A2MP1;2//1"]
[7175,9727,12.01,9.49,-0.339756158684525,{"v":1.61449914518448e-08,"d":"1.61E-08"},"*",{"v":2.10934e-09,"d":"2.11E-09"},"TPR","NA","NA","NA","K09291//nucleoprotein TPR","XP_003815642.1//PREDICTED: nucleoprotein TPR [Pan paniscus]","2//1"]
[6619,3095,9.41,7.44,-0.338892101620505,0.00836428337144965,"*",2.83906E-3,"SNAPC3","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0016604//nuclear body","GO:0003677//DNA binding","GO:0042795//snRNA transcription from RNA polymerase II promoter;GO:0009301//snRNA transcription;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006383//transcription from RNA polymerase III promoter;GO:0006366//transcription from RNA polymerase II promoter","K15210//snRNA-activating protein complex subunit 3","NP_001034786.1//snRNA-activating protein complex subunit 3 [Homo sapiens]","1//3"]
[55218,4894,6.6,5.22,-0.338416217675931,2.98756937908629E-3,"*",0.000921108,"EXD2","GO:0005634//nucleus;GO:0016021//integral component of membrane;GO:0005737//cytoplasm","GO:0008408//3'-5' exonuclease activity;GO:0008310//single-stranded DNA 3'-5' exodeoxyribonuclease activity;GO:0008852//exodeoxyribonuclease I activity;GO:0003676//nucleic acid binding","GO:0006302//double-strand break repair;GO:0000729//DNA double-strand break processing;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0000724//double-strand break repair via homologous recombination","K20777//exonuclease 3'-5' domain-containing protein 2 [EC:3.1.11.1]","NP_001180289.1//exonuclease 3'-5' domain-containing protein 2 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[23627,4038,1.39,1.1,-0.337581359198848,0.355808283612587,"*",0.21802,"PRND","GO:0031362//anchored component of external side of plasma membrane;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0005507//copper ion binding","GO:0006501//C-terminal protein lipidation;GO:0007340//acrosome reaction;GO:0006878//cellular copper ion homeostasis;GO:0051260//protein homooligomerization","K12581//CCR4-NOT transcription complex subunit 7/8;K11447//histone demethylase [EC:1.14.11.-]","XP_003779349.1//PREDICTED: LOW QUALITY PROTEIN: prion-like protein doppel [Pongo abelii]","3//A2MP1"]
[64682,7753,15.79,12.5,-0.337083076310787,{"v":9.63561772161895e-09,"d":"9.64E-09"},"*",{"v":1.222096e-09,"d":"1.22E-09"},"ANAPC1","GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005680//anaphase-promoting complex","NA","GO:0070979//protein K11-linked ubiquitination;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0051301//cell division;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle","K03348//anaphase-promoting complex subunit 1","NP_073153.1//anaphase-promoting complex subunit 1 [Homo sapiens]","3//A2MP1"]
[23150,6514,0.24,0.19,-0.337034987277571,0.626495524277141,"*",0.503228,"FRMD4B","GO:0001726//ruffle;GO:0005856//cytoskeleton;GO:0005615//extracellular space;GO:0005923//bicellular tight junction;GO:0005737//cytoplasm;GO:0005912//adherens junction","NA","GO:0090162//establishment of epithelial cell polarity","K05762//radixin;K05763//moesin","NP_055938.1//FERM domain-containing protein 4B [Homo sapiens]","2//1"]
[2000,4112,21,16.64,-0.335733894412393,{"v":3.04339912106368E-6,"d":"3.04E-06"},"*",{"v":5.44512e-07,"d":"5.45E-07"},"ELF4","GO:0005634//nucleus;GO:0016605//PML body;GO:0005654//nucleoplasm;GO:0016604//nuclear body","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0001787//natural killer cell proliferation;GO:0030154//cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0001866//NK T cell proliferation;GO:0045087//innate immune response;GO:0045893//positive regulation of transcription, DNA-templated","K09428//E74-like factor 1/2/4","NP_001412.1//ETS-related transcription factor Elf-4 [Homo sapiens]","1//3;3//A2MP1"]
[23197,4515,22.17,17.57,-0.335494578858931,{"v":3.05447094865526e-07,"d":"3.05E-07"},"*",{"v":4.69242e-08,"d":"4.69E-08"},"FAF2","GO:0034098//VCP-NPL4-UFD1 AAA ATPase complex;GO:0005783//endoplasmic reticulum;GO:0035578//azurophil granule lumen;GO:0005811//lipid droplet;GO:0005576//extracellular region","GO:0035473//lipase binding;GO:0043130//ubiquitin binding;GO:0055102//lipase inhibitor activity;GO:0031625//ubiquitin protein ligase binding","GO:0030970//retrograde protein transport, ER to cytosol;GO:0006986//response to unfolded protein;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0043312//neutrophil degranulation;GO:0034389//lipid particle organization","K18726//FAS-associated factor 2","XP_008845544.1//PREDICTED: FAS-associated factor 2 [Nannospalax galili]","2//1"]
[10206,6947,3.38,2.68,-0.334790245824412,0.0236339009081999,"*",0.00905764,"TRIM13","GO:0097038//perinuclear endoplasmic reticulum;GO:0005622//intracellular;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0044322//endoplasmic reticulum quality control compartment;GO:0005737//cytoplasm","GO:0008270//zinc ion binding;GO:0004871//signal transducer activity;GO:1904264//ubiquitin protein ligase activity involved in ERAD pathway;GO:0004842//ubiquitin-protein transferase activity","GO:0009653//anatomical structure morphogenesis;GO:1904380//endoplasmic reticulum mannose trimming;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0051260//protein homooligomerization;GO:1902187//negative regulation of viral release from host cell;GO:0010332//response to gamma radiation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0016239//positive regulation of macroautophagy;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0051865//protein autoubiquitination;GO:0032897//negative regulation of viral transcription;GO:0045087//innate immune response;GO:0010942//positive regulation of cell death","K12003//tripartite motif-containing protein 13 [EC:2.3.2.27]","NP_001007279.1//E3 ubiquitin-protein ligase TRIM13 isoform 2 [Homo sapiens]","4;3//A2MP1;2//1"]
[100528020,1561,1.5,1.19,-0.334000927187937,0.570687410628019,"*",0.414136,"FAM187A","NA","NA","NA","NA","NP_001245329.1//Ig-like V-type domain-containing protein FAM187A precursor [Homo sapiens]","1//3"]
[1314,5640,35.19,27.93,-0.333349940469715,{"v":2.62691674132492e-13,"d":"2.63E-13"},"*",{"v":2.08522e-14,"d":"2.09E-14"},"COPA","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0030126//COPI vesicle coat;GO:0005737//cytoplasm;GO:0000139//Golgi membrane;GO:0030133//transport vesicle;GO:0005829//cytosol;GO:0005789//endoplasmic reticulum membrane","GO:0005198//structural molecule activity;GO:0005179//hormone activity","GO:0006886//intracellular protein transport;GO:0030157//pancreatic juice secretion;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0016192//vesicle-mediated transport","K05236//coatomer subunit alpha","NP_001091868.1//coatomer subunit alpha isoform 1 [Homo sapiens];NP_004362.2//coatomer subunit alpha isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[83943,1256,6.75,5.36,-0.332654501480421,0.101868418983957,"*",0.047701,"IMMP2L","GO:0042720//mitochondrial inner membrane peptidase complex;GO:0016021//integral component of membrane","GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity","GO:0006801//superoxide metabolic process;GO:0006627//protein processing involved in protein targeting to mitochondrion;GO:0007283//spermatogenesis;GO:0030728//ovulation;GO:0001541//ovarian follicle development;GO:0007420//brain development;GO:0006465//signal peptide processing;GO:0008015//blood circulation;GO:0022904//respiratory electron transport chain;GO:0061300//cerebellum vasculature development;GO:0006974//cellular response to DNA damage stimulus;GO:0033108//mitochondrial respiratory chain complex assembly","K09648//mitochondrial inner membrane protease subunit 2 [EC:3.4.21.-]","XP_006071827.1//PREDICTED: mitochondrial inner membrane protease subunit 2-like isoform X1 [Bubalus bubalis];XP_009000957.1//PREDICTED: mitochondrial inner membrane protease subunit 2 isoform X1 [Callithrix jacchus];NP_115938.1//mitochondrial inner membrane protease subunit 2 isoform a [Homo sapiens];XP_006071829.1//PREDICTED: mitochondrial inner membrane protease subunit 2-like isoform X3 [Bubalus bubalis];NP_001337890.1//mitochondrial inner membrane protease subunit 2 isoform b [Homo sapiens]","1//3;3//A2MP1"]
[2048,11054,13.07,10.38,-0.332452697437552,{"v":6.37548766571916e-10,"d":"6.38E-10"},"*",{"v":7.02046e-11,"d":"7.02E-11"},"EPHB2","GO:0030425//dendrite;GO:0030424//axon;GO:0005634//nucleus;GO:0098794//postsynapse;GO:0043025//neuronal cell body;GO:0005887//integral component of plasma membrane;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0001540//amyloid-beta binding;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0005102//receptor binding;GO:0008046//axon guidance receptor activity;GO:0044877//macromolecular complex binding;GO:0004713//protein tyrosine kinase activity;GO:0005003//ephrin receptor activity;GO:0005005//transmembrane-ephrin receptor activity","GO:0031290//retinal ganglion cell axon guidance;GO:0016310//phosphorylation;GO:1904782//negative regulation of NMDA glutamate receptor activity;GO:0051965//positive regulation of synapse assembly;GO:0060997//dendritic spine morphogenesis;GO:0042472//inner ear morphogenesis;GO:1903078//positive regulation of protein localization to plasma membrane;GO:0031915//positive regulation of synaptic plasticity;GO:0007411//axon guidance;GO:0021631//optic nerve morphogenesis;GO:0022038//corpus callosum development;GO:0001525//angiogenesis;GO:0048013//ephrin receptor signaling pathway;GO:0010628//positive regulation of gene expression;GO:0048170//positive regulation of long-term neuronal synaptic plasticity;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0001933//negative regulation of protein phosphorylation;GO:0050771//negative regulation of axonogenesis;GO:0106028//neuron projection retraction;GO:0007399//nervous system development;GO:0046580//negative regulation of Ras protein signal transduction;GO:0050878//regulation of body fluid levels;GO:0048593//camera-type eye morphogenesis;GO:0051389//inactivation of MAPKK activity;GO:0048168//regulation of neuronal synaptic plasticity;GO:0071679//commissural neuron axon guidance;GO:0060021//palate development;GO:0007611//learning or memory;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0007413//axonal fasciculation;GO:1900273//positive regulation of long-term synaptic potentiation;GO:1904783//positive regulation of NMDA glutamate receptor activity;GO:0001655//urogenital system development;GO:0099557//trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission;GO:0060996//dendritic spine development;GO:0007612//learning;GO:0021952//central nervous system projection neuron axonogenesis","K05111//Eph receptor B2 [EC:2.7.10.1]","EAW95024.1//EPH receptor B2, isoform CRA_c [Homo sapiens];NP_001296121.1//ephrin type-B receptor 2 isoform 3 precursor [Homo sapiens];XP_003415418.1//PREDICTED: ephrin type-B receptor 2 isoform X1 [Loxodonta africana]","1//3;4;7"]
[10163,5721,23.64,18.78,-0.332032972523758,{"v":2.48059226382979e-09,"d":"2.48E-09"},"*",{"v":2.91944e-10,"d":"2.92E-10"},"WASF2","GO:0005856//cytoskeleton;GO:0031209//SCAR complex;GO:0070062//extracellular exosome;GO:0005622//intracellular;GO:0030027//lamellipodium;GO:0001726//ruffle;GO:0005911//cell-cell junction;GO:0005829//cytosol;GO:0043234//protein complex;GO:0015629//actin cytoskeleton;GO:0005769//early endosome","GO:0003779//actin binding;GO:0051018//protein kinase A binding;GO:0017124//SH3 domain binding;GO:0032403//protein complex binding;GO:0045296//cadherin binding","GO:0030032//lamellipodium assembly;GO:0030048//actin filament-based movement;GO:0035855//megakaryocyte development;GO:0001525//angiogenesis;GO:0030036//actin cytoskeleton organization;GO:0016032//viral process;GO:0001667//ameboidal-type cell migration;GO:0016601//Rac protein signal transduction;GO:0051497//negative regulation of stress fiber assembly;GO:0010592//positive regulation of lamellipodium assembly;GO:0006897//endocytosis;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0072673//lamellipodium morphogenesis;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway","K05748//WAS protein family, member 2","NP_001188333.1//wiskott-Aldrich syndrome protein family member 2 isoform 2 [Homo sapiens];NP_008921.1//wiskott-Aldrich syndrome protein family member 2 isoform 1 [Homo sapiens]","4;2//1"]
[113235,6480,10.73,8.53,-0.331032429438232,{"v":2.78278983129657E-5,"d":"2.78E-05"},"*",{"v":5.84466e-06,"d":"5.84E-06"},"SLC46A1","GO:0009986//cell surface;GO:0016324//apical plasma membrane;GO:0031526//brush border membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0015232//heme transporter activity;GO:0005542//folic acid binding;GO:0015350//methotrexate transmembrane transporter activity;GO:0008517//folic acid transmembrane transporter activity;GO:0015078//hydrogen ion transmembrane transporter activity;GO:0005215//transporter activity","GO:0006879//cellular iron ion homeostasis;GO:0055085//transmembrane transport;GO:0015884//folic acid transport;GO:1902600//hydrogen ion transmembrane transport;GO:1904447//folic acid import across plasma membrane;GO:0051958//methotrexate transport;GO:0046655//folic acid metabolic process;GO:0098829//intestinal folate absorption","K14613//MFS transporter, PCFT/HCP family, solute carrier family 46 (folate transporter), member 1","XP_011927771.1//PREDICTED: proton-coupled folate transporter isoform X1 [Cercocebus atys]","2//1;5"]
[727897,17916,0.44,0.35,-0.330148601692331,0.22403118772191,"*",0.12245,"MUC5B","GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005796//Golgi lumen","NA","GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0016266//O-glycan processing","K13908//mucin-5B","NP_002449.2//mucin-5B precursor [Homo sapiens]","2//1"]
[51175,2314,2.35,1.87,-0.329622486677363,0.346679106483868,"*",0.210538,"TUBE1","GO:0005874//microtubule","GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0007017//microtubule-based process","K10391//tubulin epsilon","XP_003822260.2//PREDICTED: tubulin epsilon chain isoform X1 [Pan paniscus]",4]
[9221,3950,56.07,44.64,-0.328892042637127,{"v":2.15987385763293e-14,"d":"2.16E-14"},"*",{"v":1.57657e-15,"d":"1.58E-15"},"NOLC1","GO:0005730//nucleolus;GO:0015030//Cajal body;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0005524//ATP binding;GO:0001042//RNA polymerase I core binding;GO:0046982//protein heterodimerization activity;GO:0005525//GTP binding","GO:0014032//neural crest cell development;GO:0000278//mitotic cell cycle;GO:0006364//rRNA processing;GO:0006417//regulation of translation;GO:0007409//axonogenesis;GO:0007000//nucleolus organization;GO:0014029//neural crest formation;GO:0007049//cell cycle;GO:0048167//regulation of synaptic plasticity","K11294//nucleolin","NP_001271318.1//nucleolar and coiled-body phosphoprotein 1 isoform 3 [Homo sapiens];NP_004732.2//nucleolar and coiled-body phosphoprotein 1 isoform 2 [Homo sapiens];NP_001271317.1//nucleolar and coiled-body phosphoprotein 1 isoform 1 [Homo sapiens]","1//3;4"]
[4735,3356,121.57,96.83,-0.328261257241867,{"v":6.96161665230769e-29,"d":"6.96E-29"},"*",{"v":1.982932E-30,"d":"1.98E-30"},"2019-09-02","GO:0060170//ciliary membrane;GO:0097227//sperm annulus;GO:0005737//cytoplasm;GO:0097730//non-motile cilium;GO:0030496//midbody;GO:0005730//nucleolus;GO:0000145//exocyst;GO:0005829//cytosol;GO:0005819//spindle;GO:0015629//actin cytoskeleton;GO:0000777//condensed chromosome kinetochore;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0032391//photoreceptor connecting cilium;GO:0048471//perinuclear region of cytoplasm;GO:0031105//septin complex;GO:0032154//cleavage furrow;GO:0005930//axoneme","GO:0042802//identical protein binding;GO:0005525//GTP binding;GO:0045296//cadherin binding","GO:0060271//cilium assembly;GO:0051301//cell division;GO:0031175//neuron projection development;GO:0007224//smoothened signaling pathway;GO:0007283//spermatogenesis;GO:0007049//cell cycle","K16942//septin 2","XP_011851768.1//PREDICTED: septin-2 isoform X2 [Mandrillus leucophaeus];XP_012354745.1//PREDICTED: septin-2 isoform X1 [Nomascus leucogenys];EHH21840.1//hypothetical protein EGK_04994 [Macaca mulatta];NP_001336216.1//septin-2 isoform e [Homo sapiens];XP_020930254.1//septin-2 isoform X1 [Sus scrofa];XP_008136700.1//PREDICTED: septin-2 isoform X1 [Eptesicus fuscus];XP_016859680.1//PREDICTED: septin-2 isoform X3 [Homo sapiens];NP_001269901.1//septin-2 isoform b [Homo sapiens];XP_011851766.1//PREDICTED: septin-2 isoform X1 [Mandrillus leucophaeus];NP_001307958.1//septin-2 isoform d [Homo sapiens];NP_001269902.1//septin-2 isoform c [Homo sapiens]","4;1//3;2//1"]
[27069,2449,98.19,78.24,-0.327669732813686,{"v":2.40898520258065e-15,"d":"2.41E-15"},"*",{"v":1.636252e-16,"d":"1.64E-16"},"GHITM","GO:0070062//extracellular exosome;GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion","NA","GO:0006915//apoptotic process","K21890//growth hormone-inducible transmembrane protein","NP_055209.2//growth hormone-inducible transmembrane protein [Homo sapiens]","2//1"]
[2796,2166,0.69,0.55,-0.327164743253509,0.815051180887372,"*",0.732546,"GNRH1","GO:0030425//dendrite;GO:0005615//extracellular space;GO:0043204//perikaryon;GO:1990008//neurosecretory vesicle;GO:0005576//extracellular region;GO:0005798//Golgi-associated vesicle;GO:0043679//axon terminus;GO:0005739//mitochondrion;GO:0098556//cytoplasmic side of rough endoplasmic reticulum membrane","GO:0005183//gonadotropin hormone-releasing hormone activity;GO:0005179//hormone activity","GO:0010468//regulation of gene expression;GO:1990637//response to prolactin;GO:0030238//male sex determination;GO:0034695//response to prostaglandin E;GO:0032496//response to lipopolysaccharide;GO:0044849//estrous cycle;GO:0045471//response to ethanol;GO:2000354//regulation of ovarian follicle development;GO:0033574//response to testosterone;GO:0033087//negative regulation of immature T cell proliferation;GO:0008285//negative regulation of cell proliferation;GO:0007565//female pregnancy;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0043066//negative regulation of apoptotic process;GO:0007568//aging;GO:0048545//response to steroid hormone;GO:0031960//response to corticosteroid;GO:0035864//response to potassium ion;GO:2001223//negative regulation of neuron migration;GO:0007275//multicellular organism development","K05252//gonadotropin-releasing hormone","NP_000816.4//progonadoliberin-1 isoform 1 precursor [Homo sapiens];XP_017741013.1//PREDICTED: progonadoliberin-1 isoform X1 [Rhinopithecus bieti]","1//3;3//A2MP1"]
[144100,5165,5.67,4.52,-0.327025962527041,0.0089382416046895,"*",0.00305458,"PLEKHA7","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005813//centrosome;GO:0030054//cell junction;GO:0005915//zonula adherens","GO:0070097//delta-catenin binding","GO:0045218//zonula adherens maintenance;GO:0090136//epithelial cell-cell adhesion","K05633//atrophin-1 interacting protein 5 (WW domain containing E3 ubiquitin protein ligase 1) [EC:2.3.2.26];K06245//laminin, beta 4;K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K02927//large subunit ribosomal protein L40e;K17985//activating molecule in BECN1-regulated autophagy protein 1;K15696//RING finger protein 113B","NP_778228.3//pleckstrin homology domain-containing family A member 7 isoform 2 [Homo sapiens];NP_001316560.1//pleckstrin homology domain-containing family A member 7 isoform 3 [Homo sapiens];NP_001316559.1//pleckstrin homology domain-containing family A member 7 isoform 1 [Homo sapiens]","4;1//3"]
[10009,5225,4.89,3.9,-0.326360341202623,0.0200096602736069,"*",0.00750832,"ZBTB33","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0046872//metal ion binding;GO:0043565//sequence-specific DNA binding;GO:0008327//methyl-CpG binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0016055//Wnt signaling pathway;GO:0006351//transcription, DNA-templated;GO:0035556//intracellular signal transduction","K10507//zinc finger and BTB domain-containing protein 33","NP_006768.1//transcriptional regulator Kaiso [Homo sapiens]","1//3;3//A2MP1"]
[58499,10402,1.09,0.87,-0.325240828928198,0.132266096022295,"*",0.065363,"ZNF462","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003676//nucleic acid binding","GO:0043392//negative regulation of DNA binding;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006325//chromatin organization;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","XP_021570276.1//zinc finger protein 462 isoform X3 [Carlito syrichta];NP_067047.4//zinc finger protein 462 isoform 1 [Homo sapiens]","1//3;5"]
[55610,3878,1.54,1.23,-0.324272035355662,0.529452312655087,"*",0.374004,"VPS50","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:1990745//EARP complex;GO:0055037//recycling endosome","GO:0000149//SNARE binding","GO:0032456//endocytic recycling;GO:0015031//protein transport","NA","NP_060137.2//syndetin isoform a [Homo sapiens];BAB47490.2//KIAA1861 protein, partial [Homo sapiens];NP_078829.1//syndetin isoform b [Homo sapiens]","1//3;3//A2MP1;2//1"]
[2077,2610,202.1,161.44,-0.32407124216074,{"v":3.1824875465995e-32,"d":"3.18E-32"},"*",{"v":7.9094e-34,"d":"7.91E-34"},"ERF","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0003714//transcription corepressor activity;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0001227//transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0030154//cell differentiation;GO:0006351//transcription, DNA-templated;GO:0007049//cell cycle","K09434//ETS domain-containing transcription factor ERF","XP_018870279.1//PREDICTED: ETS domain-containing transcription factor ERF isoform X1 [Gorilla gorilla gorilla];NP_006485.2//ETS domain-containing transcription factor ERF isoform 1 [Homo sapiens];ELR46668.1//ETS domain-containing transcription factor ERF, partial [Bos mutus]","1//3;3//A2MP1"]
[3621,2562,4.93,3.94,-0.323392016921535,0.132282853414418,"*",0.065363,"ING1","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0035064//methylated histone binding","GO:0030308//negative regulation of cell growth;GO:0010941//regulation of cell death;GO:0016569//covalent chromatin modification;GO:0006606//protein import into nucleus;GO:0007049//cell cycle;GO:0045893//positive regulation of transcription, DNA-templated;GO:0008285//negative regulation of cell proliferation","K19197//inhibitor of growth protein 1","NP_001254657.1//inhibitor of growth protein 1 isoform E [Homo sapiens];NP_937862.1//inhibitor of growth protein 1 isoform A [Homo sapiens];XP_009000789.1//PREDICTED: inhibitor of growth protein 1 isoform X3 [Callithrix jacchus];NP_005528.4//inhibitor of growth protein 1 isoform D [Homo sapiens]","1//3;2//1;5"]
[171546,2538,30.23,24.17,-0.322763505862124,{"v":2.23575867152398E-5,"d":"2.24E-05"},"*",{"v":4.61036e-06,"d":"4.61E-06"},"SPTSSA","NA","NA","NA","K22069//LYR motif-containing protein 4;K12581//CCR4-NOT transcription complex subunit 7/8;K12022//tripartite motif-containing protein 46;K11447//histone demethylase [EC:1.14.11.-];K08857//NIMA (never in mitosis gene a)-related kinase 1/4/5 [EC:2.7.11.1]","XP_021793619.1//serine palmitoyltransferase small subunit A [Papio anubis]","3//A2MP1"]
[57720,6915,12.14,9.71,-0.32222522083649,{"v":4.06741396435915e-06,"d":"4.07E-06"},"*",{"v":7.43002e-07,"d":"7.43E-07"},"GPR107","GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0030136//clathrin-coated vesicle;GO:0016021//integral component of membrane;GO:0005769//early endosome","GO:0032050//clathrin heavy chain binding","GO:0072583//clathrin-dependent endocytosis","K13096//splicing factor 4;K18667//activating signal cointegrator complex subunit 2","NP_001130030.1//protein GPR107 isoform 2 [Homo sapiens];NP_001130029.1//protein GPR107 isoform 1 precursor [Homo sapiens];CAI46205.1//hypothetical protein [Homo sapiens];NP_066011.2//protein GPR107 isoform 3 [Homo sapiens]","4;1//3"]
[51290,1781,18.54,14.83,-0.3221226461709,0.00816147659826216,"*",0.00276358,"ERGIC2","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005737//cytoplasm","NA","GO:0006890//retrograde vesicle-mediated transport, Golgi to ER","K20366//endoplasmic reticulum-Golgi intermediate compartment protein 2","NP_057654.2//endoplasmic reticulum-Golgi intermediate compartment protein 2 [Homo sapiens]","2//1"]
[54084,3980,0.1,0.08,-0.321928094887363,0.833860882109332,"*",0.75629,"TSPEAR","GO:0060170//ciliary membrane;GO:0009986//cell surface;GO:0032420//stereocilium;GO:0005576//extracellular region","NA","GO:0007605//sensory perception of sound","K18263//G-protein coupled receptor 98","NP_659428.2//thrombospondin-type laminin G domain and EAR repeat-containing protein isoform 1 precursor [Homo sapiens]","1//3;2//1"]
[170575,4430,0.2,0.16,-0.321928094887363,0.889590704995288,"*",0.827218,"GIMAP1","GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0000139//Golgi membrane","GO:0005525//GTP binding","NA","K09228//KRAB domain-containing zinc finger protein;K15696//RING finger protein 113B;K17985//activating molecule in BECN1-regulated autophagy protein 1;K01064//wingless-type MMTV integration site family, member 9","NP_570115.1//GTPase IMAP family member 1 [Homo sapiens]","3//A2MP1"]
[284349,2559,1.25,1,-0.321928094887362,0.507760596402878,"*",0.353468,"ZNF283","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","NP_862828.1//zinc finger protein 283 isoform 1 [Homo sapiens];XP_016882125.1//PREDICTED: zinc finger protein 283 isoform X4 [Homo sapiens]","1//3"]
[11189,5368,0.15,0.12,-0.321928094887362,0.734202172085243,"*",0.631936,"CELF3","GO:0005634//nucleus;GO:0016604//nuclear body;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0036002//pre-mRNA binding;GO:0097322//7SK snRNA binding","GO:0006397//mRNA processing;GO:0030317//flagellated sperm motility;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0030575//nuclear body organization;GO:0007283//spermatogenesis;GO:0098781//ncRNA transcription;GO:0048026//positive regulation of mRNA splicing, via spliceosome;GO:0008380//RNA splicing","K13207//CUG-BP- and ETR3-like factor","NP_001166120.1//CUGBP Elav-like family member 3 isoform 3 [Homo sapiens];BAD92501.1//trinucleotide repeat containing 4 variant, partial [Homo sapiens];EDL38738.1//trinucleotide repeat containing 4, isoform CRA_d, partial [Mus musculus]","6;1//3;3//A2MP1"]
[3607,5262,30.06,24.06,-0.321208366740288,{"v":3.98230790626831e-10,"d":"3.98E-10"},"*",{"v":4.25554E-11,"d":"4.26E-11"},"FOXK2","GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0000287//magnesium ion binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0009653//anatomical structure morphogenesis;GO:0030154//cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0016579//protein deubiquitination","K09404//forkhead box protein K","NP_004505.2//forkhead box protein K2 [Homo sapiens]","3//A2MP1"]
[54916,4278,2.31,1.85,-0.320367580899745,0.187457918246446,"*",0.099045,"TMEM260","GO:0016021//integral component of membrane","NA","NA","NA","NP_060269.3//transmembrane protein 260 [Homo sapiens]","3//A2MP1"]
[57719,4162,4.07,3.26,-0.32015683003517,0.0679194853242321,"*",0.0298992,"ANO8","GO:0005788//endoplasmic reticulum lumen;GO:0005622//intracellular;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005229//intracellular calcium activated chloride channel activity","GO:0043687//post-translational protein modification;GO:0044267//cellular protein metabolic process;GO:0006821//chloride transport;GO:0034220//ion transmembrane transport","K19502//anoctamin-8","NP_066010.1//anoctamin-8 [Homo sapiens]","2//1"]
[64110,1700,16.51,13.23,-0.319527058634581,0.0171157214890362,"*",0.00630348,"MAGEF1","GO:0070062//extracellular exosome","NA","NA","K12464//melanoma-associated antigen D1","XP_017393867.1//PREDICTED: melanoma-associated antigen F1 [Cebus capucinus imitator]",4]
[576,5356,4.71,3.78,-0.31734082539171,0.0242514458071858,"*",0.00933834,"ADGRB2","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004930//G-protein coupled receptor activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0016525//negative regulation of angiogenesis;GO:0007422//peripheral nervous system development;GO:0007166//cell surface receptor signaling pathway;GO:0051965//positive regulation of synapse assembly","K04597//brain-specific angiogenesis inhibitor 2","NP_001281264.1//adhesion G protein-coupled receptor B2 isoform 1 preproprotein [Homo sapiens];NP_001281265.1//adhesion G protein-coupled receptor B2 isoform 2 preproprotein [Homo sapiens]","1//3"]
[4200,4630,17.97,14.43,-0.316519109018744,{"v":1.23704894394904E-5,"d":"1.24E-05"},"*",{"v":2.43166e-06,"d":"2.43E-06"},"ME2","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0008948//oxaloacetate decarboxylase activity;GO:0004473//malate dehydrogenase (decarboxylating) (NADP+) activity;GO:0004471//malate dehydrogenase (decarboxylating) (NAD+) activity;GO:0009055//electron transfer activity;GO:0046872//metal ion binding;GO:0004470//malic enzyme activity;GO:0051287//NAD binding","GO:1902031//regulation of NADP metabolic process;GO:0006090//pyruvate metabolic process;GO:0006108//malate metabolic process","K00027//malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38]","NP_002387.1//NAD-dependent malic enzyme, mitochondrial isoform 1 precursor [Homo sapiens];NP_001161807.1//NAD-dependent malic enzyme, mitochondrial isoform 2 precursor [Homo sapiens]","1//3;4"]
[2733,3339,24.09,19.35,-0.316100827206698,{"v":1.88929481257707e-05,"d":"1.89E-05"},"*",{"v":3.83678e-06,"d":"3.84E-06"},"GLE1","GO:0016020//membrane;GO:0005643//nuclear pore;GO:0031965//nuclear membrane;GO:0005615//extracellular space;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0044614//nuclear pore cytoplasmic filaments;GO:0005737//cytoplasm","GO:0042802//identical protein binding;GO:0000822//inositol hexakisphosphate binding;GO:0031369//translation initiation factor binding;GO:0005543//phospholipid binding","GO:0006449//regulation of translational termination;GO:0016973//poly(A)+ mRNA export from nucleus;GO:0006406//mRNA export from nucleus;GO:0006446//regulation of translational initiation","K18723//nucleoporin GLE1","NP_001490.1//nucleoporin GLE1 isoform 2 [Homo sapiens];NP_001003722.1//nucleoporin GLE1 isoform 1 [Homo sapiens]","1//3;2//1"]
[199223,4125,0.56,0.45,-0.31550182572793,0.579583753946465,"*",0.422914,"TTC21A","NA","NA","NA","K19673//tetratricopeptide repeat protein 21B","XP_008949787.2//PREDICTED: tetratricopeptide repeat protein 21A isoform X4 [Pan paniscus]","2//1"]
[7620,1744,1.12,0.9,-0.31550182572793,0.610822361162439,"*",0.455268,"ZNF69","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","XP_001108345.3//PREDICTED: zinc finger protein 700 [Macaca mulatta]","1//3;3//A2MP1"]
[4891,3944,16.44,13.22,-0.314488122173991,{"v":9.73024388328334e-05,"d":"9.73E-05"},"*",{"v":2.23368e-05,"d":"2.23E-05"},"SLC11A2","GO:0016020//membrane;GO:0005770//late endosome;GO:0016324//apical plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0031526//brush border membrane;GO:0005741//mitochondrial outer membrane;GO:0005737//cytoplasm;GO:0070826//paraferritin complex;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0055037//recycling endosome;GO:0005886//plasma membrane;GO:0005769//early endosome;GO:0005765//lysosomal membrane;GO:0005634//nucleus;GO:0031902//late endosome membrane;GO:0005764//lysosome;GO:0005802//trans-Golgi network;GO:1903561//extracellular vesicle;GO:0005773//vacuole;GO:0048471//perinuclear region of cytoplasm;GO:0009986//cell surface;GO:0045177//apical part of cell;GO:0045178//basal part of cell","GO:0015087//cobalt ion transmembrane transporter activity;GO:0005384//manganese ion transmembrane transporter activity;GO:0046870//cadmium ion binding;GO:0015099//nickel cation transmembrane transporter activity;GO:0005375//copper ion transmembrane transporter activity;GO:0005385//zinc ion transmembrane transporter activity;GO:0005381//iron ion transmembrane transporter activity;GO:0046915//transition metal ion transmembrane transporter activity;GO:0015094//lead ion transmembrane transporter activity;GO:0015093//ferrous iron transmembrane transporter activity;GO:0015086//cadmium ion transmembrane transporter activity;GO:0022890//inorganic cation transmembrane transporter activity;GO:0015295//solute:proton symporter activity;GO:0015078//hydrogen ion transmembrane transporter activity;GO:0015100//vanadium ion transmembrane transporter activity;GO:0005215//transporter activity","GO:0006879//cellular iron ion homeostasis;GO:0015684//ferrous iron transport;GO:0015676//vanadium ion transport;GO:0006783//heme biosynthetic process;GO:0006825//copper ion transport;GO:0048821//erythrocyte development;GO:0006824//cobalt ion transport;GO:0003032//detection of oxygen;GO:0006828//manganese ion transport;GO:0007611//learning or memory;GO:0070574//cadmium ion transmembrane transport;GO:0015675//nickel cation transport;GO:0070627//ferrous iron import;GO:0060586//multicellular organismal iron ion homeostasis;GO:0010039//response to iron ion;GO:0001666//response to hypoxia;GO:0048813//dendrite morphogenesis;GO:0034599//cellular response to oxidative stress;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0015692//lead ion transport","K21398//natural resistance-associated macrophage protein 2","XP_005268968.1//PREDICTED: natural resistance-associated macrophage protein 2 isoform X1 [Homo sapiens];NP_001167596.1//natural resistance-associated macrophage protein 2 isoform 1 [Homo sapiens];NP_001167601.1//natural resistance-associated macrophage protein 2 isoform 4 [Homo sapiens]","1//3;2//1"]
[149428,2209,3.17,2.55,-0.313985593280549,0.297907066852129,"*",0.1742982,"BNIPL","GO:0005634//nucleus;GO:0005829//cytosol","GO:0042802//identical protein binding","GO:0040009//regulation of growth rate;GO:0008285//negative regulation of cell proliferation;GO:0006915//apoptotic process","K18448//BCL2/adenovirus E1B 19 kDa protein-interacting protein 2","NP_612122.2//bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein isoform a [Homo sapiens];XP_010385529.1//PREDICTED: bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein [Rhinopithecus roxellana]","1//3;3//A2MP1"]
[2960,3033,8.59,6.91,-0.313972420750205,0.0235436923006536,"*",0.00902012,"GTF2E1","GO:0097550//transcriptional preinitiation complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005669//transcription factor TFIID complex","GO:0046872//metal ion binding;GO:0043565//sequence-specific DNA binding","GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0042795//snRNA transcription from RNA polymerase II promoter;GO:0006355//regulation of transcription, DNA-templated;GO:0016032//viral process;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter","K03136//transcription initiation factor TFIIE subunit alpha","NP_005504.2//general transcription factor IIE subunit 1 [Homo sapiens]","2//1"]
[2637,1795,3.23,2.6,-0.31302254166547,0.404355258559167,"*",0.262474,"GBX2","GO:0005634//nucleus","GO:0001190//transcriptional activator activity, RNA polymerase II transcription factor binding;GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0007399//nervous system development;GO:0021549//cerebellum development;GO:0001755//neural crest cell migration;GO:0048483//autonomic nervous system development;GO:0006355//regulation of transcription, DNA-templated;GO:0021930//cerebellar granule cell precursor proliferation;GO:0042472//inner ear morphogenesis;GO:0021794//thalamus development;GO:0021568//rhombomere 2 development;GO:0001569//branching involved in blood vessel morphogenesis;GO:0021884//forebrain neuron development;GO:0021555//midbrain-hindbrain boundary morphogenesis;GO:0007411//axon guidance","K09321//homeobox protein GBX","NP_001476.2//homeobox protein GBX-2 isoform 1 [Homo sapiens];AAC03241.1//homeobox protein [Homo sapiens]","1//3;3//A2MP1"]
[51605,2353,22.06,17.77,-0.311989109562704,0.000537993446655637,"*",0.0001424972,"TRMT6","GO:0005654//nucleoplasm;GO:0031515//tRNA (m1A) methyltransferase complex","GO:0003723//RNA binding;GO:0008168//methyltransferase activity","GO:0006400//tRNA modification;GO:0030488//tRNA methylation","K03256//tRNA (adenine-N(1)-)-methyltransferase non-catalytic subunit","NP_057023.2//tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 isoform 1 [Homo sapiens]","1//3;4"]
[284716,10583,0.36,0.29,-0.31194400631474,0.43436295463138,"*",0.28769,"RIMKLA","GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0072590//N-acetyl-L-aspartate-L-glutamate ligase activity;GO:0046872//metal ion binding;GO:0005524//ATP binding;GO:0003824//catalytic activity","GO:0008652//cellular amino acid biosynthetic process;GO:0006464//cellular protein modification process","K18311//N-acetylaspartylglutamate/N-acetylaspartylglutamylglutamate synthase [EC:6.3.2.41 6.3.2.42]","XP_007977373.1//PREDICTED: N-acetylaspartylglutamate synthase A [Chlorocebus sabaeus]","3//A2MP1"]
[9166,2495,9.09,7.33,-0.310467096060295,0.0351248694945736,"*",0.01418276,"EBAG9","NA","NA","NA","NA","XP_021544046.1//receptor-binding cancer antigen expressed on SiSo cells isoform X1 [Neomonachus schauinslandi];XP_010361399.1//PREDICTED: receptor-binding cancer antigen expressed on SiSo cells isoform X1 [Rhinopithecus roxellana];XP_017747026.1//PREDICTED: receptor-binding cancer antigen expressed on SiSo cells isoform X1 [Rhinopithecus bieti]","4;1//3;2//1"]
[79188,3343,23.51,18.97,-0.309554860241546,{"v":3.48747585245902e-05,"d":"3.49E-05"},"*",{"v":7.45788e-06,"d":"7.46E-06"},"TMEM43","GO:0005788//endoplasmic reticulum lumen;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005639//integral component of nuclear inner membrane","GO:0043621//protein self-association","GO:0071763//nuclear membrane organization","NA","NP_077310.1//transmembrane protein 43 [Homo sapiens]","2//1"]
[79157,2439,28.35,22.88,-0.309261683051202,1.11489136189706E-4,"*",{"v":2.59006e-05,"d":"2.59E-05"},"MFSD11","GO:0016021//integral component of membrane","NA","NA","K16600//tubulin polyglutamylase TTLL2 [EC:6.-.-.-];K12891//splicing factor, arginine/serine-rich 2","NP_001229465.1//UNC93-like protein MFSD11 isoform 2 [Homo sapiens];NP_077287.1//UNC93-like protein MFSD11 isoform 1 [Homo sapiens]","1//3;4;2//1"]
[51326,3994,13.3,10.74,-0.308432252403139,0.00292076770445756,"*",0.000898318,"ARL17A","GO:0005794//Golgi apparatus;GO:0005622//intracellular","GO:0005525//GTP binding","GO:0007264//small GTPase mediated signal transduction;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport","K06883//uncharacterized protein","NP_001317173.1//ADP-ribosylation factor-like 17-like isoform e [Homo sapiens];BAD92581.1//ADP-ribosylation factor 7 variant, partial [Homo sapiens];NP_001275740.1//ADP-ribosylation factor-like 17-like isoform c [Homo sapiens];NP_001096624.1//ADP-ribosylation factor-like protein 17 isoform b [Homo sapiens]","1//3;2//1"]
[84901,3877,15.42,12.46,-0.307498696891032,4.22864900120686E-4,"*",0.0001096738,"NFATC2IP","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0031386//protein tag","GO:0016925//protein sumoylation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0001816//cytokine production","K12581//CCR4-NOT transcription complex subunit 7/8;K17985//activating molecule in BECN1-regulated autophagy protein 1","NP_116204.3//NFATC2-interacting protein [Homo sapiens]","3//A2MP1"]
[161829,3114,1.2,0.97,-0.306977753421391,0.475819093328439,"*",0.32459,"EXD1","GO:0043186//P granule;GO:1990923//PET complex","GO:0003723//RNA binding;GO:0042803//protein homodimerization activity","GO:0051321//meiotic cell cycle;GO:0031047//gene silencing by RNA;GO:0034587//piRNA metabolic process","K18740//exonuclease 3'-5' domain-containing protein 1","NP_001273370.1//piRNA biogenesis protein EXD1 isoform 1 [Homo sapiens];XP_017750933.1//PREDICTED: piRNA biogenesis protein EXD1 isoform X1 [Rhinopithecus bieti]","1//3;3//A2MP1"]
[4026,17872,3.98,3.22,-0.305707742429032,{"v":4.45416244297616E-5,"d":"4.45E-05"},"*",{"v":9.70636e-06,"d":"9.71E-06"},"LPP","GO:0005634//nucleus;GO:0005925//focal adhesion;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0046872//metal ion binding","GO:0007155//cell adhesion","K16676//lipoma-prefererred partner","XP_021789580.1//lipoma-preferred partner isoform X2 [Papio anubis];XP_011511125.1//PREDICTED: lipoma-preferred partner isoform X1 [Homo sapiens];NP_001161144.1//lipoma-preferred partner isoform b [Homo sapiens]","4;2//1"]
[27297,2705,17.21,13.93,-0.305051839438951,1.75743316346564E-3,"*",0.000515546,"CRCP","GO:0005654//nucleoplasm;GO:0009360//DNA polymerase III complex;GO:0005829//cytosol;GO:0001669//acrosomal vesicle;GO:0005666//DNA-directed RNA polymerase III complex;GO:0005886//plasma membrane","GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0001635//calcitonin gene-related peptide receptor activity;GO:0000166//nucleotide binding","GO:0032481//positive regulation of type I interferon production;GO:0051607//defense response to virus;GO:0006384//transcription initiation from RNA polymerase III promoter;GO:0007218//neuropeptide signaling pathway;GO:0045087//innate immune response;GO:0006383//transcription from RNA polymerase III promoter","K01368//cathepsin S [EC:3.4.22.27];K08857//NIMA (never in mitosis gene a)-related kinase 1/4/5 [EC:2.7.11.1]","NP_001135886.1//DNA-directed RNA polymerase III subunit RPC9 isoform d [Homo sapiens];XP_011959811.1//PREDICTED: DNA-directed RNA polymerase III subunit RPC9 isoform X3 [Ovis aries];XP_009451439.1//PREDICTED: DNA-directed RNA polymerase III subunit RPC9 isoform X2 [Pan troglodytes]","4;1//3"]
[120224,1946,0.21,0.17,-0.304854581528421,0.833630724537676,"*",0.75629,"TMEM45B","GO:0016021//integral component of membrane","NA","NA","K01312//trypsin [EC:3.4.21.4]","NP_620143.1//transmembrane protein 45B [Homo sapiens]","4;1//3"]
[84317,1865,10.19,8.25,-0.304688027032636,0.0983530972885906,"*",0.0458702,"CCDC115","GO:0016020//membrane;GO:0005768//endosome;GO:0042406//extrinsic component of endoplasmic reticulum membrane;GO:0005783//endoplasmic reticulum;GO:0005764//lysosome;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0030137//COPI-coated vesicle;GO:0016471//vacuolar proton-transporting V-type ATPase complex","GO:0051082//unfolded protein binding","GO:1905146//lysosomal protein catabolic process;GO:0006879//cellular iron ion homeostasis;GO:0007042//lysosomal lumen acidification;GO:0036295//cellular response to increased oxygen levels","K22020//mucin-19;K18772//C->U-editing enzyme APOBEC2 [EC:3.5.4.-];K07297//adiponectin receptor","NP_115733.2//coiled-coil domain-containing protein 115 isoform a [Homo sapiens];NP_001308047.1//coiled-coil domain-containing protein 115 isoform b [Homo sapiens];XP_003909333.1//coiled-coil domain-containing protein 115 [Papio anubis]","1//3;3//A2MP1"]
[54861,4888,1.79,1.45,-0.303906687249322,0.243318967011456,"*",0.1369526,"SNRK","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0000287//magnesium ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding","GO:0006468//protein phosphorylation;GO:0030099//myeloid cell differentiation;GO:0035556//intracellular signal transduction","K08802//SNF related kinase [EC:2.7.11.1]","AAF86944.1//HSNFRK [Homo sapiens];CAH18415.1//hypothetical protein [Homo sapiens]","1//3;4"]
[6528,3594,2.32,1.88,-0.303392143449935,0.294597541607717,"*",0.1720668,"SLC5A5","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:1903561//extracellular vesicle","GO:0015111//iodide transmembrane transporter activity;GO:0008507//sodium:iodide symporter activity","GO:0006810//transport;GO:0015705//iodide transport;GO:0071371//cellular response to gonadotropin stimulus;GO:0006590//thyroid hormone generation;GO:0006811//ion transport;GO:0071320//cellular response to cAMP","K14385//solute carrier family 5 (sodium/iodide cotransporter), member 5","NP_000444.1//sodium/iodide cotransporter [Homo sapiens]","2//1"]
[4131,11749,23.03,18.67,-0.302792483566644,{"v":2.78529698422018e-15,"d":"2.79E-15"},"*",{"v":1.900572e-16,"d":"1.90E-16"},"MAP1B","GO:0005874//microtubule;GO:0030054//cell junction;GO:0014069//postsynaptic density;GO:0001750//photoreceptor outer segment;GO:0005875//microtubule associated complex;GO:0005829//cytosol;GO:0043197//dendritic spine;GO:0005886//plasma membrane","GO:0005198//structural molecule activity;GO:0008017//microtubule binding","GO:0007399//nervous system development;GO:0000226//microtubule cytoskeleton organization;GO:0048675//axon extension;GO:0016358//dendrite development;GO:0047497//mitochondrion transport along microtubule;GO:0061162//establishment of monopolar cell polarity;GO:0045773//positive regulation of axon extension;GO:0032387//negative regulation of intracellular transport;GO:0009987//cellular process;GO:0001578//microtubule bundle formation","K10429//microtubule-associated protein 1","NP_005900.2//microtubule-associated protein 1B isoform 1 [Homo sapiens];XP_011728513.1//PREDICTED: microtubule-associated protein 1B isoform X1 [Macaca nemestrina]","1//3;4"]
[54962,1295,11,8.92,-0.302387908491717,0.134297774545455,"*",0.0665856,"TIPIN","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031298//replication fork protection complex;GO:0000790//nuclear chromatin;GO:0005737//cytoplasm","GO:0003677//DNA binding","GO:0009411//response to UV;GO:0033262//regulation of nuclear cell cycle DNA replication;GO:0006260//DNA replication;GO:0048478//replication fork protection;GO:0000076//DNA replication checkpoint;GO:0031573//intra-S DNA damage checkpoint;GO:0044770//cell cycle phase transition;GO:0051301//cell division;GO:0043111//replication fork arrest;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0008284//positive regulation of cell proliferation","K10904//TIMELESS-interacting protein","NP_060328.2//TIMELESS-interacting protein isoform 1 [Homo sapiens];XP_005254578.1//PREDICTED: TIMELESS-interacting protein isoform X1 [Homo sapiens]","1//3;2//1"]
[340371,3723,13.26,10.76,-0.301402697555964,1.87285401485884E-3,"*",0.000552336,"NRBP2","GO:0012505//endomembrane system;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity","GO:0030182//neuron differentiation;GO:0006468//protein phosphorylation;GO:0043524//negative regulation of neuron apoptotic process;GO:0035556//intracellular signal transduction;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0016242//negative regulation of macroautophagy","K08875//nuclear receptor-binding protein","XP_012328731.1//nuclear receptor-binding protein 2 isoform X1 [Aotus nancymaae]","3//A2MP1"]
[220134,2919,19.71,16,-0.300855871268761,0.000691210462549156,"*",0.0001870604,"SKA1","GO:0015630//microtubule cytoskeleton;GO:0005829//cytosol;GO:0000940//condensed chromosome outer kinetochore;GO:0005876//spindle microtubule","GO:0008017//microtubule binding","GO:0000278//mitotic cell cycle;GO:0007059//chromosome segregation;GO:0007062//sister chromatid cohesion;GO:0031110//regulation of microtubule polymerization or depolymerization;GO:0051301//cell division","K17985//activating molecule in BECN1-regulated autophagy protein 1","NP_659497.1//spindle and kinetochore-associated protein 1 [Homo sapiens]","3//A2MP1;2//1"]
[11004,2877,19.9,16.16,-0.300341232679216,{"v":2.90073966091612e-05,"d":"2.90E-05"},"*",{"v":6.1051e-06,"d":"6.11E-06"},"KIF2C","GO:0016020//membrane;GO:0005654//nucleoplasm;GO:0005874//microtubule;GO:0035371//microtubule plus-end;GO:0015630//microtubule cytoskeleton;GO:0005813//centrosome;GO:0000775//chromosome, centromeric region;GO:0005829//cytosol;GO:0000777//condensed chromosome kinetochore;GO:0000776//kinetochore;GO:0005871//kinesin complex","GO:0019237//centromeric DNA binding;GO:0005524//ATP binding;GO:0051010//microtubule plus-end binding;GO:0003777//microtubule motor activity;GO:0008017//microtubule binding;GO:0016887//ATPase activity","GO:0051983//regulation of chromosome segregation;GO:0000278//mitotic cell cycle;GO:0007018//microtubule-based movement;GO:0051315//attachment of mitotic spindle microtubules to kinetochore;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0007019//microtubule depolymerization;GO:0007080//mitotic metaphase plate congression;GO:0008283//cell proliferation;GO:0007062//sister chromatid cohesion;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0051301//cell division;GO:0030951//establishment or maintenance of microtubule cytoskeleton polarity;GO:0051310//metaphase plate congression","K10393//kinesin family member 2/24","NP_001284584.1//kinesin-like protein KIF2C isoform 2 [Homo sapiens];NP_001284585.1//kinesin-like protein KIF2C isoform 3 [Homo sapiens];NP_006836.2//kinesin-like protein KIF2C isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[6666,4658,58.57,47.57,-0.300109869147063,{"v":6.81460178210806E-15,"d":"6.81E-15"},"*",{"v":4.81638e-16,"d":"4.82E-16"},"SOX12","GO:0005654//nucleoplasm;GO:0032993//protein-DNA complex","GO:0001105//RNA polymerase II transcription coactivator activity;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0000976//transcription regulatory region sequence-specific DNA binding","GO:0065004//protein-DNA complex assembly;GO:0045165//cell fate commitment;GO:0021510//spinal cord development","K09268//transcription factor SOX4/11/12 (SOX group C)","XP_017370646.1//PREDICTED: transcription factor SOX-12 [Cebus capucinus imitator]","3//A2MP1"]
[55763,3514,4.43,3.6,-0.299309792225343,0.0988304993828817,"*",0.0461176,"EXOC1","GO:0016020//membrane;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0030496//midbody;GO:0000145//exocyst;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0098592//cytoplasmic side of apical plasma membrane","GO:0017049//GTP-Rho binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding","GO:0016241//regulation of macroautophagy;GO:0051601//exocyst localization;GO:0051607//defense response to virus;GO:0016032//viral process;GO:0006893//Golgi to plasma membrane transport;GO:0050714//positive regulation of protein secretion;GO:0048015//phosphatidylinositol-mediated signaling;GO:0015031//protein transport;GO:0006887//exocytosis","K19983//exocyst complex component 1","NP_060731.2//exocyst complex component 1 isoform 1 [Homo sapiens];NP_839955.1//exocyst complex component 1 isoform 2 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[23279,5197,9.62,7.82,-0.298868286462689,{"v":2.06815571583786e-07,"d":"2.07E-07"},"*",{"v":3.09822e-08,"d":"3.10E-08"},"NUP160","GO:0043657//host cell;GO:0005643//nuclear pore;GO:0005635//nuclear envelope;GO:0005829//cytosol;GO:0031080//nuclear pore outer ring","GO:0005487//nucleocytoplasmic transporter activity","GO:0006406//mRNA export from nucleus;GO:0007077//mitotic nuclear envelope disassembly;GO:0016925//protein sumoylation;GO:0060964//regulation of gene silencing by miRNA;GO:0006409//tRNA export from nucleus;GO:0016032//viral process;GO:0006110//regulation of glycolytic process;GO:1900034//regulation of cellular response to heat;GO:0007062//sister chromatid cohesion;GO:0019083//viral transcription;GO:0075733//intracellular transport of virus","K14303//nuclear pore complex protein Nup160","NP_001305328.1//nuclear pore complex protein Nup160 isoform 2 [Homo sapiens];NP_056046.1//nuclear pore complex protein Nup160 isoform 1 [Homo sapiens]","1//3;2//1"]
[23438,2509,14.58,11.86,-0.297886709780933,0.00915605149542962,"*",3.13532E-3,"HARS2","NA","NA","NA","K01892//histidyl-tRNA synthetase [EC:6.1.1.21]","XP_011795050.1//PREDICTED: probable histidine--tRNA ligase, mitochondrial isoform X4 [Colobus angolensis palliatus];XP_010386476.1//PREDICTED: probable histidine--tRNA ligase, mitochondrial isoform X3 [Rhinopithecus roxellana];XP_010342742.1//PREDICTED: probable histidine--tRNA ligase, mitochondrial isoform X2 [Saimiri boliviensis boliviensis]","1//3;3//A2MP1"]
[5792,7716,29.49,24,-0.297191416565856,{"v":2.05961826957787e-12,"d":"2.06E-12"},"*",{"v":1.771576E-13,"d":"1.77E-13"},"PTPRF","NA","NA","NA","K05695//receptor-type tyrosine-protein phosphatase F [EC:3.1.3.48]","NP_001316066.1//receptor-type tyrosine-protein phosphatase F isoform 3 precursor [Homo sapiens];NP_001316067.1//receptor-type tyrosine-protein phosphatase F isoform 4 precursor [Homo sapiens];NP_001316069.1//receptor-type tyrosine-protein phosphatase F isoform 6 precursor [Homo sapiens];XP_011934472.1//PREDICTED: receptor-type tyrosine-protein phosphatase F isoform X8 [Cercocebus atys];NP_001316068.1//receptor-type tyrosine-protein phosphatase F isoform 5 precursor [Homo sapiens];XP_011934473.1//PREDICTED: receptor-type tyrosine-protein phosphatase F isoform X9 [Cercocebus atys]","4;1//3;3//A2MP1"]
[3416,5513,12.16,9.9,-0.296642798476613,{"v":1.38496353373185e-07,"d":"1.38E-07"},"*",{"v":2.03054e-08,"d":"2.03E-08"},"IDE","GO:0005634//nucleus;GO:0005615//extracellular space;GO:0005782//peroxisomal matrix;GO:0031597//cytosolic proteasome complex;GO:0005777//peroxisome;GO:0005737//cytoplasm;GO:0009986//cell surface;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005886//plasma membrane","GO:0031626//beta-endorphin binding;GO:0001540//amyloid-beta binding;GO:0004222//metalloendopeptidase activity;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0005102//receptor binding;GO:0042277//peptide binding;GO:0042803//protein homodimerization activity;GO:0043559//insulin binding;GO:0140036//ubiquitin-dependent protein binding;GO:0008270//zinc ion binding;GO:0001618//virus receptor activity;GO:0016887//ATPase activity","GO:1901143//insulin catabolic process;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0045861//negative regulation of proteolysis;GO:0008286//insulin receptor signaling pathway;GO:0097242//amyloid-beta clearance;GO:0051260//protein homooligomerization;GO:0050435//amyloid-beta metabolic process;GO:0042447//hormone catabolic process;GO:1901142//insulin metabolic process;GO:0010815//bradykinin catabolic process;GO:0051291//protein heterooligomerization;GO:0051289//protein homotetramerization;GO:0032461//positive regulation of protein oligomerization;GO:0008340//determination of adult lifespan;GO:0006508//proteolysis;GO:0045732//positive regulation of protein catabolic process;GO:0010992//ubiquitin recycling","K01408//insulysin [EC:3.4.24.56]","XP_014387048.1//PREDICTED: insulin-degrading enzyme isoform X1 [Myotis brandtii];XP_016774359.1//PREDICTED: insulin-degrading enzyme isoform X4 [Pan troglodytes];XP_003922440.2//PREDICTED: insulin-degrading enzyme isoform X1 [Saimiri boliviensis boliviensis];XP_016871679.1//PREDICTED: insulin-degrading enzyme isoform X2 [Homo sapiens];NP_001309723.1//insulin-degrading enzyme isoform 4 [Homo sapiens];NP_004960.2//insulin-degrading enzyme isoform 1 [Homo sapiens];NP_001309722.1//insulin-degrading enzyme isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[2776,6343,7.43,6.05,-0.296427068376639,0.00272052277459016,"*",0.00083111,"GNAQ","GO:0016020//membrane;GO:0005765//lysosomal membrane;GO:0070062//extracellular exosome;GO:0030425//dendrite;GO:0031965//nuclear membrane;GO:0005834//heterotrimeric G-protein complex;GO:0001750//photoreceptor outer segment;GO:0044297//cell body;GO:0005901//caveola;GO:0043234//protein complex;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0003924//GTPase activity;GO:0031683//G-protein beta/gamma-subunit complex binding;GO:0046872//metal ion binding;GO:0001664//G-protein coupled receptor binding;GO:0031826//type 2A serotonin receptor binding;GO:0047391//alkylglycerophosphoethanolamine phosphodiesterase activity;GO:0005525//GTP binding;GO:0004871//signal transducer activity;GO:0005096//GTPase activator activity;GO:0032403//protein complex binding","GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0043267//negative regulation of potassium ion transport;GO:0050796//regulation of insulin secretion;GO:0042733//embryonic digit morphogenesis;GO:0045634//regulation of melanocyte differentiation;GO:0043065//positive regulation of apoptotic process;GO:0048066//developmental pigmentation;GO:0009791//post-embryonic development;GO:0070208//protein heterotrimerization;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0021884//forebrain neuron development;GO:0007215//glutamate receptor signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007213//G-protein coupled acetylcholine receptor signaling pathway;GO:0035412//regulation of catenin import into nucleus;GO:0007507//heart development;GO:0009649//entrainment of circadian clock;GO:0043066//negative regulation of apoptotic process;GO:0060158//phospholipase C-activating dopamine receptor signaling pathway;GO:0006469//negative regulation of protein kinase activity;GO:0007603//phototransduction, visible light;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0007202//activation of phospholipase C activity;GO:0001508//action potential;GO:0001501//skeletal system development;GO:0050821//protein stabilization;GO:0042711//maternal behavior;GO:0016322//neuron remodeling","K04634//guanine nucleotide-binding protein G(q) subunit alpha","XP_020040613.1//guanine nucleotide-binding protein G(q) subunit alpha [Castor canadensis]",4]
[8569,2680,8.69,7.08,-0.295606816731403,0.0793865442176871,"*",0.035797,"MKNK1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004683//calmodulin-dependent protein kinase activity;GO:0009931//calcium-dependent protein serine/threonine kinase activity;GO:0005516//calmodulin binding","GO:0018105//peptidyl-serine phosphorylation;GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction;GO:0006417//regulation of translation;GO:0046777//protein autophosphorylation","K04372//MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]","NP_003675.2//MAP kinase-interacting serine/threonine-protein kinase 1 isoform 1 [Homo sapiens];XP_018873451.1//PREDICTED: MAP kinase-interacting serine/threonine-protein kinase 1 isoform X2 [Gorilla gorilla gorilla];XP_018873478.1//PREDICTED: MAP kinase-interacting serine/threonine-protein kinase 1 isoform X6 [Gorilla gorilla gorilla]","3//A2MP1;2//1;5"]
[22889,3009,13.02,10.61,-0.295304792250871,0.00759766164276402,"*",0.00255364,"KHDC4","GO:0005634//nucleus;GO:0005681//spliceosomal complex;GO:0030529//intracellular ribonucleoprotein complex;GO:0019013//viral nucleocapsid;GO:0005737//cytoplasm","GO:0003723//RNA binding","GO:0006376//mRNA splice site selection","K13095//splicing factor 1;K16882//protein piccolo","NP_055764.2//UPF0469 protein KIAA0907 [Homo sapiens]","3//A2MP1"]
[908,2681,108.56,88.5,-0.294743265561132,{"v":3.59406318478261e-15,"d":"3.59E-15"},"*",{"v":2.48394E-16,"d":"2.48E-16"},"CCT6A","GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0005874//microtubule;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005832//chaperonin-containing T-complex","GO:0003723//RNA binding;GO:0005524//ATP binding;GO:0071987//WD40-repeat domain binding;GO:0051082//unfolded protein binding;GO:0044183//protein binding involved in protein folding","GO:0006457//protein folding;GO:1904874//positive regulation of telomerase RNA localization to Cajal body;GO:1904851//positive regulation of establishment of protein localization to telomere;GO:1904871//positive regulation of protein localization to Cajal body;GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0006458//'de novo' protein folding;GO:0050821//protein stabilization;GO:0061077//chaperone-mediated protein folding","K09498//T-complex protein 1 subunit zeta","NP_001009186.1//T-complex protein 1 subunit zeta isoform b [Homo sapiens];XP_012304540.1//T-complex protein 1 subunit zeta [Aotus nancymaae]","1//3;3//A2MP1"]
[153090,5196,11.17,9.11,-0.294106226681264,0.00276713601963993,"*",0.000846736,"DAB2IP","GO:0044301//climbing fiber;GO:0030424//axon;GO:0044300//cerebellar mossy fiber;GO:1990597//AIP1-IRE1 complex","GO:0071889//14-3-3 protein binding;GO:0005123//death receptor binding;GO:0005096//GTPase activator activity;GO:0045296//cadherin binding","GO:0001525//angiogenesis;GO:0016525//negative regulation of angiogenesis;GO:0007257//activation of JUN kinase activity;GO:0000185//activation of MAPKKK activity;GO:0043065//positive regulation of apoptotic process;GO:0030948//negative regulation of vascular endothelial growth factor receptor signaling pathway;GO:0038026//reelin-mediated signaling pathway;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0008285//negative regulation of cell proliferation","K19901//disabled homolog 2-interacting protein","NP_115941.2//disabled homolog 2-interacting protein isoform 1 [Homo sapiens];XP_016817061.1//PREDICTED: disabled homolog 2-interacting protein isoform X2 [Pan troglodytes]","3//A2MP1;2//1"]
[54969,1233,15.41,12.57,-0.293882212094278,0.0846298693102024,"*",0.0384792,"HPF1","GO:0005634//nucleus","GO:0042393//histone binding","GO:0018312//peptidyl-serine ADP-ribosylation;GO:0010835//regulation of protein ADP-ribosylation;GO:0006974//cellular response to DNA damage stimulus","K10380//ankyrin","NP_060337.2//histone PARylation factor 1 [Homo sapiens]","2//1"]
[842,2720,3.75,3.06,-0.293358942690591,0.328563065232825,"*",0.1970062,"CASP9","GO:0005634//nucleus;GO:0043293//apoptosome;GO:0043234//protein complex;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005737//cytoplasm","GO:0008233//peptidase activity;GO:0042802//identical protein binding;GO:0004197//cysteine-type endopeptidase activity;GO:0017124//SH3 domain binding;GO:0008047//enzyme activator activity;GO:0019901//protein kinase binding;GO:0097200//cysteine-type endopeptidase activity involved in execution phase of apoptosis","GO:0034349//glial cell apoptotic process;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0032496//response to lipopolysaccharide;GO:2001020//regulation of response to DNA damage stimulus;GO:0046677//response to antibiotic;GO:0034644//cellular response to UV;GO:0043065//positive regulation of apoptotic process;GO:0032355//response to estradiol;GO:0030220//platelet formation;GO:0006974//cellular response to DNA damage stimulus;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0043525//positive regulation of neuron apoptotic process;GO:0007568//aging;GO:0006915//apoptotic process;GO:0071549//cellular response to dexamethasone stimulus;GO:0032025//response to cobalt ion;GO:0042770//signal transduction in response to DNA damage;GO:0097194//execution phase of apoptosis;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0008635//activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c","K04399//caspase 9 [EC:3.4.22.62]","BAD92384.1//caspase 9 isoform alpha preproprotein variant, partial [Homo sapiens];NP_001220.2//caspase-9 isoform alpha precursor [Homo sapiens];NP_001264983.1//caspase-9 isoform beta [Homo sapiens]","1//3;4;3//A2MP1"]
[11279,8397,0.49,0.4,-0.292781749227846,0.446172816753927,"*",0.298752,"KLF8","GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016235//aggresome","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated","K09205//krueppel-like factor 8/12","XP_016798882.1//PREDICTED: Krueppel-like factor 8 isoform X1 [Pan troglodytes];NP_001311028.1//Krueppel-like factor 8 isoform 3 [Homo sapiens];NP_001311029.1//Krueppel-like factor 8 isoform 4 [Homo sapiens];XP_008957781.1//PREDICTED: Krueppel-like factor 8 isoform X1 [Pan paniscus];XP_016798883.1//PREDICTED: Krueppel-like factor 8 isoform X2 [Pan troglodytes]","1//3;2//1;5"]
[90843,1164,20.76,16.95,-0.292521170334175,0.0444193252476734,"*",0.0185252,"TCEAL8","GO:0005634//nucleus","GO:0050699//WW domain binding;GO:0003746//translation elongation factor activity","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated","NA","NP_699164.1//transcription elongation factor A protein-like 8 [Homo sapiens]","1//3;2//1"]
[26225,3102,13,10.62,-0.291727857111663,0.00904100944231121,"*",0.00309536,"ARL5A","GO:0005622//intracellular","GO:0005525//GTP binding","GO:1903292//protein localization to Golgi membrane;GO:0007264//small GTPase mediated signal transduction","K07949//ADP-ribosylation factor-like protein 5A","XP_004842625.1//ADP-ribosylation factor-like protein 5A [Heterocephalus glaber];EDL26907.1//ADP-ribosylation factor-like 5A, partial [Mus musculus];NP_036229.1//ADP-ribosylation factor-like protein 5A isoform 1 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[1810,3222,11.21,9.16,-0.291366774708483,0.0119214902980837,"*",0.00420618,"DR1","GO:0005634//nucleus;GO:0005671//Ada2/Gcn5/Ada3 transcription activator complex","GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0017025//TBP-class protein binding;GO:0046982//protein heterodimerization activity;GO:0008134//transcription factor binding","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0043966//histone H3 acetylation;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K21751//down-regulator of transcription 1","XP_011746186.1//PREDICTED: uncharacterized protein LOC105485493 [Macaca nemestrina]","2//1"]
[64225,4035,21.07,17.22,-0.291105171420462,{"v":4.78970913898305e-06,"d":"4.79E-06"},"*",{"v":8.8454E-7,"d":"8.85E-07"},"ATL2","GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0098826//endoplasmic reticulum tubular network membrane","GO:0042802//identical protein binding;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:1990809//endoplasmic reticulum tubular network membrane organization;GO:0051260//protein homooligomerization;GO:0007030//Golgi organization;GO:0007029//endoplasmic reticulum organization","K17339//atlastin [EC:3.6.5.-]","NP_001317392.1//atlastin-2 isoform 8 [Homo sapiens];NP_001317391.1//atlastin-2 isoform 7 [Homo sapiens];NP_001317388.1//atlastin-2 isoform 5 [Homo sapiens];NP_071769.2//atlastin-2 isoform 1 [Homo sapiens];XP_012330934.1//atlastin-2 isoform X1 [Aotus nancymaae];XP_012509310.1//PREDICTED: atlastin-2 isoform X1 [Propithecus coquereli];XP_012330936.1//atlastin-2 isoform X3 [Aotus nancymaae];NP_001129145.1//atlastin-2 isoform 2 [Homo sapiens];NP_001295005.1//atlastin-2 isoform 3 [Homo sapiens]","4;1//3;3//A2MP1"]
[51001,1470,18.46,15.1,-0.289854003433333,0.0355407288256228,"*",0.0143796,"MTERF3","GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane","GO:0044212//transcription regulatory region DNA binding;GO:0003690//double-stranded DNA binding;GO:0003727//single-stranded RNA binding;GO:0019843//rRNA binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0032502//developmental process;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0008380//RNA splicing;GO:0042255//ribosome assembly;GO:0016236//macroautophagy","K15032//mTERF domain-containing protein, mitochondrial","NP_001273572.1//transcription termination factor 3, mitochondrial isoform 2 precursor [Homo sapiens];NP_057026.3//transcription termination factor 3, mitochondrial isoform 1 precursor [Homo sapiens]","1//3;4"]
[202,7562,0.33,0.27,-0.289506617194985,0.587483076739427,"*",0.431326,"CRYBG1","NA","NA","NA","K04257//olfactory receptor;K16810//TBCC domain-containing protein 1","XP_005266896.1//PREDICTED: absent in melanoma 1 protein isoform X1 [Homo sapiens]","3//A2MP1"]
[145447,1477,0.33,0.27,-0.289506617194985,0.66970232336605,"*",0.551014,"ABHD12B","NA","GO:0016787//hydrolase activity","NA","K13705//abhydrolase domain-containing protein 12B","XP_007984854.1//PREDICTED: abhydrolase domain-containing protein 12B isoform X2 [Chlorocebus sabaeus];NP_001193602.1//protein ABHD12B isoform a [Homo sapiens];NP_861535.1//protein ABHD12B isoform c [Homo sapiens]","1//3;3//A2MP1"]
[51808,3641,12.73,10.42,-0.28887714162285,0.00397847085182987,"*",1.258994E-3,"PHAX","NA","NA","NA","K14291//phosphorylated adapter RNA export protein","EAW48850.1//RNA U, small nuclear RNA export adaptor (phosphorylation regulated), partial [Homo sapiens]","3//A2MP1"]
[6804,2138,36.14,29.61,-0.287512015687046,0.000160684259425587,"*",{"v":3.85264e-05,"d":"3.85E-05"},"STX1A","GO:0030054//cell junction;GO:0048787//presynaptic active zone membrane;GO:0070044//synaptobrevin 2-SNAP-25-syntaxin-1a complex;GO:0005887//integral component of plasma membrane;GO:0030672//synaptic vesicle membrane;GO:0005829//cytosol;GO:0005576//extracellular region;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0030424//axon;GO:0031965//nuclear membrane;GO:0008021//synaptic vesicle;GO:0014069//postsynaptic density;GO:0043005//neuron projection;GO:0070032//synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex;GO:0030141//secretory granule;GO:0042641//actomyosin;GO:0031201//SNARE complex;GO:0070033//synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex","GO:0000149//SNARE binding;GO:0005484//SNAP receptor activity;GO:0019855//calcium channel inhibitor activity;GO:0047485//protein N-terminus binding;GO:0030674//protein binding, bridging;GO:0046982//protein heterodimerization activity;GO:0043008//ATP-dependent protein binding;GO:0044325//ion channel binding;GO:0019904//protein domain specific binding;GO:0019869//chloride channel inhibitor activity;GO:0019900//kinase binding;GO:0017022//myosin binding;GO:0048306//calcium-dependent protein binding;GO:0032028//myosin head/neck binding","GO:0010701//positive regulation of norepinephrine secretion;GO:0072657//protein localization to membrane;GO:0009629//response to gravity;GO:0050796//regulation of insulin secretion;GO:0007269//neurotransmitter secretion;GO:0001956//positive regulation of neurotransmitter secretion;GO:0010807//regulation of synaptic vesicle priming;GO:0048278//vesicle docking;GO:0035493//SNARE complex assembly;GO:0031629//synaptic vesicle fusion to presynaptic active zone membrane;GO:0045956//positive regulation of calcium ion-dependent exocytosis;GO:0032940//secretion by cell;GO:0033605//positive regulation of catecholamine secretion;GO:2000463//positive regulation of excitatory postsynaptic potential;GO:0006886//intracellular protein transport;GO:0016081//synaptic vesicle docking;GO:0014047//glutamate secretion","K04560//syntaxin 1A","NP_001159375.1//syntaxin-1A isoform 2 [Homo sapiens];XP_002743976.1//PREDICTED: syntaxin-1A isoform X1 [Callithrix jacchus]","1//3;3//A2MP1"]
[23355,5052,3.49,2.86,-0.287211889431263,0.0847734726321586,"*",0.0385498,"VPS8","GO:0005769//early endosome;GO:0033263//CORVET complex","GO:0046872//metal ion binding","GO:0034058//endosomal vesicle fusion;GO:0015031//protein transport","K20178//vacuolar protein sorting-associated protein 8","NP_056118.2//vacuolar protein sorting-associated protein 8 homolog isoform b [Homo sapiens];NP_001336225.1//vacuolar protein sorting-associated protein 8 homolog isoform c [Homo sapiens];NP_001009921.1//vacuolar protein sorting-associated protein 8 homolog isoform a [Homo sapiens];XP_016015197.1//PREDICTED: vacuolar protein sorting-associated protein 8 homolog isoform X4 [Rousettus aegyptiacus]","1//3;3//A2MP1;2//1"]
[5213,3443,17.64,14.46,-0.286783008606403,1.447380894383E-3,"*",0.000417796,"PFKM","GO:0070062//extracellular exosome;GO:0016324//apical plasma membrane;GO:0005829//cytosol;GO:0097228//sperm principal piece;GO:0005945//6-phosphofructokinase complex;GO:0005737//cytoplasm","GO:0070061//fructose binding;GO:0046872//metal ion binding;GO:0003872//6-phosphofructokinase activity;GO:0008022//protein C-terminus binding;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0019900//kinase binding;GO:0042803//protein homodimerization activity","GO:0061621//canonical glycolysis;GO:0032024//positive regulation of insulin secretion;GO:0005980//glycogen catabolic process;GO:0093001//glycolysis from storage polysaccharide through glucose-1-phosphate;GO:0006096//glycolytic process;GO:0046716//muscle cell cellular homeostasis;GO:0042593//glucose homeostasis;GO:0006002//fructose 6-phosphate metabolic process;GO:0051259//protein oligomerization","K00850//6-phosphofructokinase 1 [EC:2.7.1.11]","NP_001341664.1//ATP-dependent 6-phosphofructokinase, muscle type isoform 3 [Homo sapiens];NP_001341675.1//ATP-dependent 6-phosphofructokinase, muscle type isoform 7 [Homo sapiens];NP_001160158.1//ATP-dependent 6-phosphofructokinase, muscle type isoform 1 [Homo sapiens];XP_016779021.1//PREDICTED: ATP-dependent 6-phosphofructokinase, muscle type isoform X4 [Pan troglodytes];NP_001341669.1//ATP-dependent 6-phosphofructokinase, muscle type isoform 4 [Homo sapiens];NP_001341676.1//ATP-dependent 6-phosphofructokinase, muscle type isoform 8 [Homo sapiens]","1//3;5"]
[1977,10386,7.34,6.02,-0.286016576083511,1.22317398929336E-4,"*",{"v":2.86076E-5,"d":"2.86E-05"},"EIF4E","GO:0070062//extracellular exosome;GO:0010494//cytoplasmic stress granule;GO:0000932//P-body;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0005845//mRNA cap binding complex;GO:0033391//chromatoid body;GO:0005829//cytosol;GO:0016442//RISC complex;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0016281//eukaryotic translation initiation factor 4F complex","GO:0003743//translation initiation factor activity;GO:0003723//RNA binding;GO:0000339//RNA cap binding;GO:0000340//RNA 7-methylguanosine cap binding;GO:0070491//repressing transcription factor binding;GO:0019899//enzyme binding;GO:0031370//eukaryotic initiation factor 4G binding","GO:0006406//mRNA export from nucleus;GO:0030324//lung development;GO:0045931//positive regulation of mitotic cell cycle;GO:0016032//viral process;GO:0006417//regulation of translation;GO:0006405//RNA export from nucleus;GO:0071549//cellular response to dexamethasone stimulus;GO:0001662//behavioral fear response;GO:0006413//translational initiation;GO:0045665//negative regulation of neuron differentiation;GO:0019827//stem cell population maintenance;GO:0017148//negative regulation of translation;GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0000082//G1/S transition of mitotic cell cycle","K03259//translation initiation factor 4E","NP_001124151.1//eukaryotic translation initiation factor 4E isoform 2 [Homo sapiens];NP_001317946.1//eukaryotic translation initiation factor 4E isoform 4 [Homo sapiens];XP_005964407.1//PREDICTED: eukaryotic translation initiation factor 4E [Pantholops hodgsonii];NP_001124150.1//eukaryotic translation initiation factor 4E isoform 3 [Homo sapiens]","1//3;4;2//1"]
[80196,1982,17.69,14.51,-0.285886528623714,0.00258539173542139,"*",0.000785458,"RNF34","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016607//nuclear speck;GO:0005737//cytoplasm;GO:0012505//endomembrane system;GO:0005829//cytosol;GO:0016604//nuclear body;GO:0005886//plasma membrane","GO:0061630//ubiquitin protein ligase activity;GO:1901981//phosphatidylinositol phosphate binding;GO:0046872//metal ion binding;GO:0002039//p53 binding;GO:0031625//ubiquitin protein ligase binding;GO:0016874//ligase activity","GO:0070936//protein K48-linked ubiquitination;GO:1901797//negative regulation of signal transduction by p53 class mediator;GO:2000374//regulation of oxygen metabolic process;GO:0016567//protein ubiquitination;GO:0070417//cellular response to cold;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0006915//apoptotic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:2001271//negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis","K20804//E3 ubiquitin-protein ligase RNF34 [EC:2.3.2.27]","XP_021569924.1//E3 ubiquitin-protein ligase RNF34 isoform X3 [Carlito syrichta];NP_919247.1//E3 ubiquitin-protein ligase RNF34 isoform 1 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[10664,3665,20.54,16.86,-0.284831645376113,{"v":8.75004488645418e-09,"d":"8.75E-09"},"*",{"v":1.099918E-9,"d":"1.10E-09"},"CTCF","GO:0000793//condensed chromosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0000775//chromosome, centromeric region","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003714//transcription corepressor activity;GO:0043035//chromatin insulator sequence binding;GO:0044212//transcription regulatory region DNA binding;GO:0003676//nucleic acid binding;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0008270//zinc ion binding;GO:0003700//DNA binding transcription factor activity","GO:0045892//negative regulation of transcription, DNA-templated;GO:0010216//maintenance of DNA methylation;GO:0040029//regulation of gene expression, epigenetic;GO:0035065//regulation of histone acetylation;GO:0071459//protein localization to chromosome, centromeric region;GO:0007059//chromosome segregation;GO:0006349//regulation of gene expression by genetic imprinting;GO:0070602//regulation of centromeric sister chromatid cohesion;GO:0010628//positive regulation of gene expression;GO:0006306//DNA methylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0016584//nucleosome positioning;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0031060//regulation of histone methylation;GO:0016569//covalent chromatin modification;GO:0040030//regulation of molecular function, epigenetic","K09228//KRAB domain-containing zinc finger protein","XP_013969561.1//transcriptional repressor CTCF isoform X1 [Canis lupus familiaris];NP_006556.1//transcriptional repressor CTCF isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[54069,1587,13.95,11.46,-0.283658077959645,0.0679666103796389,"*",0.0299242,"MIS18A","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0000785//chromatin;GO:0000775//chromosome, centromeric region","GO:0046872//metal ion binding","GO:0007059//chromosome segregation;GO:1903955//positive regulation of protein targeting to mitochondrion;GO:0051301//cell division;GO:0044030//regulation of DNA methylation;GO:0034080//CENP-A containing nucleosome assembly;GO:0007049//cell cycle","K11564//kinetochore protein Mis18","NP_061817.1//protein Mis18-alpha [Homo sapiens]","2//1"]
[1459,1719,15.24,12.52,-0.283628340560704,0.0438923274710744,"*",0.01828618,"CSNK2A2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031519//PcG protein complex;GO:0005829//cytosol;GO:0000785//chromatin;GO:0001669//acrosomal vesicle;GO:0005886//plasma membrane","GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0047485//protein N-terminus binding","GO:0006457//protein folding;GO:0097421//liver regeneration;GO:0006355//regulation of transcription, DNA-templated;GO:1903955//positive regulation of protein targeting to mitochondrion;GO:0006351//transcription, DNA-templated;GO:1905818//regulation of chromosome separation;GO:1903146//regulation of autophagy of mitochondrion;GO:0007283//spermatogenesis;GO:0006915//apoptotic process;GO:1901796//regulation of signal transduction by p53 class mediator;GO:0021987//cerebral cortex development;GO:0016055//Wnt signaling pathway;GO:0007049//cell cycle;GO:0006656//phosphatidylcholine biosynthetic process;GO:0016236//macroautophagy","K03097//casein kinase II subunit alpha [EC:2.7.11.1]","NP_001887.1//casein kinase II subunit alpha' [Homo sapiens]","3//A2MP1"]
[57167,4006,1.18,0.97,-0.282730207174714,0.311458955391433,"*",0.1848008,"SALL4","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0043234//protein complex;GO:0000792//heterochromatin;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0043565//sequence-specific DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0008134//transcription factor binding;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0007165//signal transduction;GO:0006355//regulation of transcription, DNA-templated;GO:0035019//somatic stem cell population maintenance;GO:0030326//embryonic limb morphogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0022008//neurogenesis;GO:0001833//inner cell mass cell proliferation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0001843//neural tube closure;GO:0003281//ventricular septum development","K19871//sal-like protein","NP_001304960.1//sal-like protein 4 isoform 2 [Homo sapiens];NP_065169.1//sal-like protein 4 isoform 1 [Homo sapiens]","4;1//3"]
[56648,5537,4.4,3.62,-0.281513826441454,0.0507275235875498,"*",0.0215276,"EIF5A2","NA","NA","NA","K03263//translation initiation factor 5A","ELK13603.1//Eukaryotic translation initiation factor 5A-2 [Pteropus alecto]",5]
[8629,9124,3.73,3.07,-0.280936974885058,1.45199628706625E-4,"*",{"v":3.45774e-05,"d":"3.46E-05"},"JRK","GO:0005634//nucleus;GO:0030529//intracellular ribonucleoprotein complex;GO:0005737//cytoplasm","GO:0003729//mRNA binding;GO:0003677//DNA binding","NA","K09228//KRAB domain-containing zinc finger protein;K09229//KRAB and SCAN domains-containing zinc finger protein;K19326//nesprin-1;K05164//interleukin 17 receptor A","NP_003715.3//jerky protein homolog isoform a [Homo sapiens];NP_001070995.2//jerky protein homolog isoform b [Homo sapiens]","1//3;3//A2MP1;2//1"]
[6288,579,0.51,0.42,-0.280107919192735,0.782763473661762,"*",0.689316,"SAA1","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0034364//high-density lipoprotein particle;GO:0005881//cytoplasmic microtubule;GO:0005576//extracellular region;GO:0071682//endocytic vesicle lumen","GO:0001664//G-protein coupled receptor binding;GO:0008201//heparin binding;GO:0042056//chemoattractant activity","GO:0048247//lymphocyte chemotaxis;GO:0030593//neutrophil chemotaxis;GO:0000187//activation of MAPK activity;GO:0045785//positive regulation of cell adhesion;GO:0006953//acute-phase response;GO:0030168//platelet activation;GO:0050716//positive regulation of interleukin-1 secretion;GO:0050728//negative regulation of inflammatory response;GO:0044267//cellular protein metabolic process;GO:0006898//receptor-mediated endocytosis;GO:0050708//regulation of protein secretion;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0048246//macrophage chemotaxis;GO:0050715//positive regulation of cytokine secretion;GO:0045087//innate immune response","K17310//serum amyloid A protein","XP_002822026.1//PREDICTED: serum amyloid A-1 protein [Pongo abelii];NP_954630.1//serum amyloid A-1 protein preproprotein [Homo sapiens]","4;2//1;5"]
[1054,3725,17.7,14.58,-0.279758640643423,1.01911339433162E-3,"*",0.00028588,"CEBPG","NA","NA","NA","K10049//CCAAT/enhancer binding protein (C/EBP), gamma","XP_012303880.1//CCAAT/enhancer-binding protein gamma isoform X1 [Aotus nancymaae];XP_004999640.1//PREDICTED: LOW QUALITY PROTEIN: CCAAT/enhancer-binding protein gamma-like [Cavia porcellus]","1//3;3//A2MP1"]
[28231,2796,7.27,5.99,-0.279399361130809,0.085360582841455,"*",0.038929,"SLCO4A1","NA","NA","NA","K14354//solute carrier organic anion transporter family, member 4A","XP_003904570.1//solute carrier organic anion transporter family member 4A1 [Papio anubis]","3//A2MP1"]
[79627,8875,3.64,3,-0.278975949702815,0.0238781969577281,"*",0.00915874,"OGFRL1","GO:0016020//membrane","GO:0004872//receptor activity","NA","K06245//laminin, beta 4;K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K01064//wingless-type MMTV integration site family, member 9;K12025//tripartite motif-containing protein 52","NP_078852.3//opioid growth factor receptor-like protein 1 isoform b [Homo sapiens];NP_001311195.1//opioid growth factor receptor-like protein 1 isoform a [Homo sapiens]","1//3;4"]
[4298,4530,22.25,18.35,-0.278025273010547,{"v":2.22895528432564E-5,"d":"2.23E-05"},"*",{"v":4.59354e-06,"d":"4.59E-06"},"MLLT1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0008023//transcription elongation factor complex;GO:0005829//cytosol;GO:0001650//fibrillar center","GO:0003677//DNA binding","GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0006469//negative regulation of protein kinase activity;GO:0006355//regulation of transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter","K15187//YEATS domain-containing protein 1/3","NP_005925.2//protein ENL [Homo sapiens]","3//A2MP1"]
[29109,3865,23.68,19.53,-0.277977131742158,{"v":5.87682738826185e-05,"d":"5.88E-05"},"*",{"v":1.303836e-05,"d":"1.30E-05"},"FHOD1","GO:0016020//membrane;GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0001725//stress fiber;GO:0032059//bleb;GO:0005829//cytosol;GO:0014704//intercalated disc","GO:0003779//actin binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0043621//protein self-association","GO:0051496//positive regulation of stress fiber assembly;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0051660//establishment of centrosome localization;GO:0051492//regulation of stress fiber assembly;GO:0007097//nuclear migration","K05740//diaphanous 1;K05741//diaphanous 2","NP_001305131.1//FH1/FH2 domain-containing protein 1 isoform 1 [Homo sapiens];NP_037373.2//FH1/FH2 domain-containing protein 1 isoform 2 [Homo sapiens]","1//3;2//1"]
[5780,3963,21.47,17.73,-0.276129654960085,0.000122351951310861,"*",{"v":2.8631e-05,"d":"2.86E-05"},"PTPN9","GO:0005737//cytoplasm","GO:0004726//non-membrane spanning protein tyrosine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity","GO:0006470//protein dephosphorylation","K18038//tyrosine-protein phosphatase non-receptor type 9 [EC:3.1.3.48]","XP_003901277.2//tyrosine-protein phosphatase non-receptor type 9 [Papio anubis]","3//A2MP1"]
[1592,2119,0.23,0.19,-0.275634442613427,0.849755121790922,"*",0.777036,"CYP26A1","GO:0031090//organelle membrane;GO:0005789//endoplasmic reticulum membrane","GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen;GO:0020037//heme binding;GO:0008401//retinoic acid 4-hydroxylase activity;GO:0005506//iron ion binding;GO:0004497//monooxygenase activity;GO:0001972//retinoic acid binding;GO:0019825//oxygen binding","GO:0042573//retinoic acid metabolic process;GO:0006766//vitamin metabolic process;GO:0034653//retinoic acid catabolic process;GO:0048387//negative regulation of retinoic acid receptor signaling pathway;GO:0006805//xenobiotic metabolic process;GO:0016125//sterol metabolic process","K07437//cytochrome P450 family 26 subfamily A","NP_000774.2//cytochrome P450 26A1 isoform 1 [Homo sapiens]","3//A2MP1;2//1"]
[59283,8751,3.92,3.24,-0.274859841230583,0.0201917534555148,"*",0.00758676,"CACNG8","NA","NA","NA","K04873//voltage-dependent calcium channel gamma-8","XP_012355367.1//PREDICTED: voltage-dependent calcium channel gamma-8 subunit [Nomascus leucogenys]",5]
[10283,2073,8.09,6.69,-0.274133491788517,0.118450537916667,"*",0.0569488,"CWC27","GO:0005654//nucleoplasm;GO:0071013//catalytic step 2 spliceosome","GO:0003755//peptidyl-prolyl cis-trans isomerase activity","GO:0006457//protein folding;GO:0000398//mRNA splicing, via spliceosome","K12737//peptidyl-prolyl cis-trans isomerase SDCCAG10 [EC:5.2.1.8]","NP_001284574.1//peptidyl-prolyl cis-trans isomerase CWC27 homolog isoform 3 [Homo sapiens];NP_005860.2//peptidyl-prolyl cis-trans isomerase CWC27 homolog isoform 1 [Homo sapiens];NP_001284573.1//peptidyl-prolyl cis-trans isomerase CWC27 homolog isoform 2 [Homo sapiens];NP_001304929.1//peptidyl-prolyl cis-trans isomerase CWC27 homolog isoform 4 [Homo sapiens]","1//3;3//A2MP1"]
[84128,2716,26.84,22.2,-0.273824994962715,0.000491202022783603,"*",0.0001290274,"WDR75","GO:0005654//nucleoplasm;GO:0005730//nucleolus","GO:0003723//RNA binding","GO:1903955//positive regulation of protein targeting to mitochondrion;GO:0006351//transcription, DNA-templated;GO:1903146//regulation of autophagy of mitochondrion;GO:0045943//positive regulation of transcription from RNA polymerase I promoter;GO:0006364//rRNA processing;GO:2000234//positive regulation of rRNA processing","K14552//NET1-associated nuclear protein 1 (U3 small nucleolar RNA-associated protein 17)","NP_115544.1//WD repeat-containing protein 75 isoform 1 [Homo sapiens];NP_001290025.1//WD repeat-containing protein 75 isoform 2 [Homo sapiens]","1//3;2//1"]
[374786,3762,0.29,0.24,-0.273018494406416,0.678654070335001,"*",0.560546,"EFCAB5","NA","GO:0005509//calcium ion binding","NA","K12022//tripartite motif-containing protein 46;K14000//ribosome-binding protein 1;K04739//cAMP-dependent protein kinase regulator","XP_016880081.1//PREDICTED: EF-hand calcium-binding domain-containing protein 5 isoform X7 [Homo sapiens];NP_940931.2//EF-hand calcium-binding domain-containing protein 5 isoform a [Homo sapiens]","1//3;3//A2MP1"]
[57030,2993,0.93,0.77,-0.27237227041313,0.617528495269987,"*",0.461774,"SLC17A7","GO:0048786//presynaptic active zone;GO:0098794//postsynapse;GO:0060076//excitatory synapse;GO:0030054//cell junction;GO:0044300//cerebellar mossy fiber;GO:0030672//synaptic vesicle membrane;GO:0060203//clathrin-sculpted glutamate transport vesicle membrane;GO:0016021//integral component of membrane;GO:0030285//integral component of synaptic vesicle membrane;GO:0005886//plasma membrane","GO:0005313//L-glutamate transmembrane transporter activity;GO:0015319//sodium:inorganic phosphate symporter activity;GO:0005315//inorganic phosphate transmembrane transporter activity;GO:0015321//sodium-dependent phosphate transmembrane transporter activity;GO:0008068//extracellularly glutamate-gated chloride channel activity","GO:0055085//transmembrane transport;GO:0006811//ion transport;GO:0007420//brain development;GO:0007616//long-term memory;GO:0051938//L-glutamate import;GO:0003407//neural retina development;GO:0098700//neurotransmitter loading into synaptic vesicle;GO:0006817//phosphate ion transport;GO:0042137//sequestering of neurotransmitter;GO:0035249//synaptic transmission, glutamatergic;GO:0097401//synaptic vesicle lumen acidification;GO:0014047//glutamate secretion","K12302//MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6/7/8","NP_064705.1//vesicular glutamate transporter 1 [Homo sapiens]","3//A2MP1"]
[284406,5974,1.92,1.59,-0.272079545436801,0.615672279872633,"*",0.459962,"ZFP82","GO:0005634//nucleus;GO:0005622//intracellular","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","NP_001308848.1//zinc finger protein 82 homolog isoform 4 [Homo sapiens];NP_001308847.1//zinc finger protein 82 homolog isoform 3 [Homo sapiens];XP_014927523.1//PREDICTED: uncharacterized protein LOC106974738 [Acinonyx jubatus]","1//3;3//A2MP1"]
[338707,3463,9.22,7.64,-0.271194112393589,0.0298571347000952,"*",0.01177912,"B4GALNT4","GO:0032580//Golgi cisterna membrane;GO:0016021//integral component of membrane","GO:0033842//N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity;GO:0008376//acetylgalactosaminyltransferase activity","NA","K09657//beta-1,4-N-acetylgalactosaminyltransferase 4 [EC:2.4.1.244]","NP_848632.2//N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 [Homo sapiens]",4]
[11022,2794,4.15,3.44,-0.270702771532189,0.22930685984252,"*",0.127616,"TDRKH","GO:0071547//piP-body;GO:0071546//pi-body;GO:0005739//mitochondrion","GO:0003723//RNA binding","GO:0007140//male meiotic nuclear division;GO:0009566//fertilization;GO:0030154//cell differentiation;GO:0043046//DNA methylation involved in gamete generation;GO:0031047//gene silencing by RNA;GO:0007283//spermatogenesis;GO:0034587//piRNA metabolic process","K18406//tudor domain-containing protein 2","NP_001077433.1//tudor and KH domain-containing protein isoform b [Homo sapiens];AAD30971.1//putative RNA binding protein [Homo sapiens]","1//3;3//A2MP1"]
[10888,4178,0.41,0.34,-0.270089163367744,0.647372546966431,"*",0.52636,"GPR83","GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0097730//non-motile cilium","GO:0004983//neuropeptide Y receptor activity;GO:0004930//G-protein coupled receptor activity","GO:0051384//response to glucocorticoid","K04210//G protein-coupled receptor 83","NP_057624.3//probable G-protein coupled receptor 83 isoform 1 precursor [Homo sapiens];NP_001317274.1//probable G-protein coupled receptor 83 isoform 2 precursor [Homo sapiens]","1//3;3//A2MP1"]
[51144,2556,36.96,30.67,-0.269136590149038,{"v":8.3364763059989e-05,"d":"8.34E-05"},"*",{"v":1.896504e-05,"d":"1.90E-05"},"HSD17B12","GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005578//proteinaceous extracellular matrix","GO:0102341//3-oxo-lignoceroyl-CoA reductase activity;GO:0001968//fibronectin binding;GO:0102340//3-oxo-behenoyl-CoA reductase activity;GO:0102339//3-oxo-arachidoyl-CoA reductase activity;GO:0005518//collagen binding;GO:0102342//3-oxo-cerotoyl-CoA reductase activity;GO:0004303//estradiol 17-beta-dehydrogenase activity;GO:0016509//long-chain-3-hydroxyacyl-CoA dehydrogenase activity;GO:0008201//heparin binding;GO:0016491//oxidoreductase activity","GO:0030198//extracellular matrix organization;GO:0035338//long-chain fatty-acyl-CoA biosynthetic process;GO:0006633//fatty acid biosynthetic process;GO:0006703//estrogen biosynthetic process;GO:0010811//positive regulation of cell-substrate adhesion","K10251//17beta-estradiol 17-dehydrogenase / very-long-chain 3-oxoacyl-CoA reductase [EC:1.1.1.62 1.1.1.330]","NP_057226.1//very-long-chain 3-oxoacyl-CoA reductase [Homo sapiens]","2//1"]
[4173,4803,59.27,49.2,-0.26864374194101,{"v":1.03965907473842E-12,"d":"1.04E-12"},"*",{"v":8.7083e-14,"d":"8.71E-14"},"MCM4","GO:0016020//membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000784//nuclear chromosome, telomeric region;GO:0042555//MCM complex","GO:0003677//DNA binding;GO:0003697//single-stranded DNA binding;GO:0005524//ATP binding;GO:0003678//DNA helicase activity;GO:0004003//ATP-dependent DNA helicase activity","GO:0006260//DNA replication;GO:0000082//G1/S transition of mitotic cell cycle;GO:0006268//DNA unwinding involved in DNA replication;GO:0006270//DNA replication initiation","K02212//DNA replication licensing factor MCM4 [EC:3.6.4.12]","CAA52801.1//P1 Cdc21 protein, partial [Homo sapiens]","3//A2MP1;2//1"]
[93109,2419,4.72,3.92,-0.267933205246633,0.229281068946125,"*",0.127616,"TMEM44","GO:0016020//membrane","NA","NA","NA","NP_001159777.1//transmembrane protein 44 isoform c [Homo sapiens];NP_001011655.1//transmembrane protein 44 isoform b [Homo sapiens];NP_001159778.1//transmembrane protein 44 isoform d [Homo sapiens];NP_612408.3//transmembrane protein 44 isoform a [Homo sapiens]","1//3;4;2//1"]
[1540,8614,1.36,1.13,-0.267283878835152,0.218994498113208,"*",0.1191624,"CYLD","GO:0005874//microtubule;GO:0005813//centrosome;GO:0048471//perinuclear region of cytoplasm;GO:0036064//ciliary basal body;GO:0097542//ciliary tip;GO:0005829//cytosol;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0005819//spindle;GO:0005886//plasma membrane","GO:0061578//Lys63-specific deubiquitinase activity;GO:0004843//thiol-dependent ubiquitin-specific protease activity;GO:0008270//zinc ion binding;GO:0036459//thiol-dependent ubiquitinyl hydrolase activity;GO:1990380//Lys48-specific deubiquitinase activity;GO:0070064//proline-rich region binding;GO:0019901//protein kinase binding","GO:0070507//regulation of microtubule cytoskeleton organization;GO:0007346//regulation of mitotic cell cycle;GO:1902017//regulation of cilium assembly;GO:0010803//regulation of tumor necrosis factor-mediated signaling pathway;GO:1903829//positive regulation of cellular protein localization;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0045581//negative regulation of T cell differentiation;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination;GO:0045582//positive regulation of T cell differentiation;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:0045087//innate immune response;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0070536//protein K63-linked deubiquitination;GO:0043369//CD4-positive or CD8-positive, alpha-beta T cell lineage commitment;GO:0048872//homeostasis of number of cells;GO:0043393//regulation of protein binding;GO:0045577//regulation of B cell differentiation;GO:0070423//nucleotide-binding oligomerization domain containing signaling pathway;GO:1901026//ripoptosome assembly involved in necroptotic process;GO:1990108//protein linear deubiquitination;GO:2001242//regulation of intrinsic apoptotic signaling pathway;GO:0042347//negative regulation of NF-kappaB import into nucleus;GO:0016055//Wnt signaling pathway;GO:0070266//necroptotic process;GO:0032480//negative regulation of type I interferon production;GO:0007049//cell cycle;GO:0050862//positive regulation of T cell receptor signaling pathway","K08601//ubiquitin thioesterase [EC:3.4.19.12]","NP_056062.1//ubiquitin carboxyl-terminal hydrolase CYLD isoform 1 [Homo sapiens];NP_001035814.1//ubiquitin carboxyl-terminal hydrolase CYLD isoform 2 [Homo sapiens]","1//3;2//1"]
[2295,2187,16.3,13.55,-0.266579112877206,0.0242520644617886,"*",0.00933706,"FOXF2","GO:0005634//nucleus;GO:0005667//transcription factor complex","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0008134//transcription factor binding;GO:0003700//DNA binding transcription factor activity;GO:0003705//transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0009653//anatomical structure morphogenesis;GO:0030154//cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0042249//establishment of planar polarity of embryonic epithelium;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0030198//extracellular matrix organization;GO:0048806//genitalia development;GO:0048566//embryonic digestive tract development;GO:0001837//epithelial to mesenchymal transition;GO:0060021//palate development;GO:0048596//embryonic camera-type eye morphogenesis","K09399//forkhead box protein F","NP_001443.1//forkhead box protein F2 [Homo sapiens]","1//3"]
[23032,4440,7.12,5.92,-0.266280065337448,0.033148299155194,"*",0.0132643,"USP33","GO:0005654//nucleoplasm;GO:0005925//focal adhesion;GO:0030891//VCB complex;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0044297//cell body;GO:0005829//cytosol;GO:0005794//Golgi apparatus","GO:0004843//thiol-dependent ubiquitin-specific protease activity;GO:0001664//G-protein coupled receptor binding;GO:0004197//cysteine-type endopeptidase activity;GO:0008270//zinc ion binding;GO:0036459//thiol-dependent ubiquitinyl hydrolase activity;GO:0017160//Ral GTPase binding","GO:0071108//protein K48-linked deubiquitination;GO:0016477//cell migration;GO:0009267//cellular response to starvation;GO:0051298//centrosome duplication;GO:0032092//positive regulation of protein binding;GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0032091//negative regulation of protein binding;GO:0006897//endocytosis;GO:0016579//protein deubiquitination;GO:0010506//regulation of autophagy;GO:0050821//protein stabilization;GO:0007411//axon guidance;GO:0070536//protein K63-linked deubiquitination","K11848//ubiquitin carboxyl-terminal hydrolase 20/33 [EC:3.4.19.12]","NP_963920.1//ubiquitin carboxyl-terminal hydrolase 33 isoform 3 [Homo sapiens];NP_055832.3//ubiquitin carboxyl-terminal hydrolase 33 isoform 1 [Homo sapiens]","4;2//1"]
[10058,3045,14.11,11.74,-0.265285579487212,0.0196162642969403,"*",0.00734474,"ABCB6","NA","NA","NA","K05661//ATP-binding cassette, subfamily B (MDR/TAP), member 6","AAG33617.1//ATP-binding cassette half-transporter [Homo sapiens];NP_001336757.1//ATP-binding cassette sub-family B member 6, mitochondrial isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[8562,2731,33.71,28.06,-0.264661618364311,0.000137916461278394,"*",{"v":3.26876e-05,"d":"3.27E-05"},"DENR","NA","GO:0003743//translation initiation factor activity","NA","K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K02927//large subunit ribosomal protein L40e;K01064//wingless-type MMTV integration site family, member 9","XP_021018633.1//density-regulated protein isoform X1 [Mus caroli]",4]
[9909,5688,19.85,16.53,-0.264052282738006,{"v":1.86758654478073e-05,"d":"1.87E-05"},"*",{"v":3.78568e-06,"d":"3.79E-06"},"DENND4B","GO:0005634//nucleus;GO:0005794//Golgi apparatus;GO:0005829//cytosol","GO:0017112//Rab guanyl-nucleotide exchange factor activity","GO:0032483//regulation of Rab protein signal transduction;GO:0061024//membrane organization","K20163//DENN domain-containing protein 4","XP_005245735.1//PREDICTED: DENN domain-containing protein 4B isoform X3 [Homo sapiens]","2//1"]
[9122,2006,16.07,13.39,-0.263213968350783,0.0124331952194606,"*",4.41552E-3,"SLC16A4","GO:0016020//membrane;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane","GO:0008028//monocarboxylic acid transmembrane transporter activity;GO:0015293//symporter activity","GO:0055085//transmembrane transport;GO:0015718//monocarboxylic acid transport","K08181//MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 4","NP_001188477.1//monocarboxylate transporter 5 isoform 4 [Homo sapiens];NP_001306149.1//monocarboxylate transporter 5 isoform 6 [Homo sapiens];NP_001188478.1//monocarboxylate transporter 5 isoform 5 [Homo sapiens];NP_001188475.1//monocarboxylate transporter 5 isoform 2 [Homo sapiens];NP_004687.1//monocarboxylate transporter 5 isoform 1 [Homo sapiens];NP_001188476.1//monocarboxylate transporter 5 isoform 3 [Homo sapiens]","1//3;2//1"]
[165055,2262,3.3,2.75,-0.263034405833794,0.33139061375,"*",0.199158,"CCDC138","NA","NA","NA","K21110//cingulin-like protein 1;K11167//dehydrogenase/reductase SDR family member 7C [EC:1.1.-.-];K10421//CAP-Gly domain-containing linker protein 1;K16461//centrosomal protein CEP135;K20478//golgin subfamily B member 1","NP_001338490.1//coiled-coil domain-containing protein 138 isoform 14 [Homo sapiens];NP_001338480.1//coiled-coil domain-containing protein 138 isoform 8 [Homo sapiens];NP_001338486.1//coiled-coil domain-containing protein 138 isoform 12 [Homo sapiens];NP_001338473.1//coiled-coil domain-containing protein 138 isoform 4 [Homo sapiens];NP_001338482.1//coiled-coil domain-containing protein 138 isoform 9 [Homo sapiens];NP_001338477.1//coiled-coil domain-containing protein 138 isoform 6 [Homo sapiens];NP_001338483.1//coiled-coil domain-containing protein 138 isoform 10 [Homo sapiens];NP_001338474.1//coiled-coil domain-containing protein 138 isoform 5 [Homo sapiens];NP_001338484.1//coiled-coil domain-containing protein 138 isoform 11 [Homo sapiens];NP_001338488.1//coiled-coil domain-containing protein 138 isoform 13 [Homo sapiens];NP_001290034.1//coiled-coil domain-containing protein 138 isoform 2 [Homo sapiens];NP_659415.1//coiled-coil domain-containing protein 138 isoform 1 [Homo sapiens];NP_001338478.1//coiled-coil domain-containing protein 138 isoform 7 [Homo sapiens]","1//3;2//1"]
[23543,6800,13.21,11.01,-0.262815997682459,0.000307467393449132,"*",{"v":7.75694e-05,"d":"7.76E-05"},"RBFOX2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003714//transcription corepressor activity;GO:0008134//transcription factor binding","GO:0043484//regulation of RNA splicing;GO:0016070//RNA metabolic process;GO:0007399//nervous system development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006397//mRNA processing;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0010724//regulation of definitive erythrocyte differentiation;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0042127//regulation of cell proliferation;GO:0021942//radial glia guided migration of Purkinje cell;GO:0048813//dendrite morphogenesis;GO:0008380//RNA splicing;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0050885//neuromuscular process controlling balance","K14946//RNA binding protein fox-1","NP_001076048.1//RNA binding protein fox-1 homolog 2 isoform 6 [Homo sapiens];NP_001076047.1//RNA binding protein fox-1 homolog 2 isoform 5 [Homo sapiens];NP_001336912.1//RNA binding protein fox-1 homolog 2 isoform 7 [Homo sapiens];NP_001026865.1//RNA binding protein fox-1 homolog 2 isoform 1 [Homo sapiens];NP_001336923.1//RNA binding protein fox-1 homolog 2 isoform 13 [Homo sapiens];NP_001336928.1//RNA binding protein fox-1 homolog 2 isoform 18 [Homo sapiens];NP_001336911.1//RNA binding protein fox-1 homolog 2 isoform 8 [Homo sapiens];NP_055124.1//RNA binding protein fox-1 homolog 2 isoform 2 [Homo sapiens];NP_001336927.1//RNA binding protein fox-1 homolog 2 isoform 17 [Homo sapiens];NP_001336920.1//RNA binding protein fox-1 homolog 2 isoform 11 [Homo sapiens];NP_001336925.1//RNA binding protein fox-1 homolog 2 isoform 15 [Homo sapiens];NP_001336926.1//RNA binding protein fox-1 homolog 2 isoform 16 [Homo sapiens];NP_001336924.1//RNA binding protein fox-1 homolog 2 isoform 14 [Homo sapiens];NP_001336921.1//RNA binding protein fox-1 homolog 2 isoform 12 [Homo sapiens];NP_001076046.1//RNA binding protein fox-1 homolog 2 isoform 4 [Homo sapiens];NP_001076045.1//RNA binding protein fox-1 homolog 2 isoform 3 [Homo sapiens];AAI49448.1//RBM9 protein, partial [Bos taurus];NP_001336918.1//RNA binding protein fox-1 homolog 2 isoform 9 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[1315,3419,35.18,29.33,-0.262378411715005,{"v":1.10024571739827e-05,"d":"1.10E-05"},"*",{"v":2.14966e-06,"d":"2.15E-06"},"COPB1","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0030667//secretory granule membrane;GO:0030126//COPI vesicle coat;GO:0019028//viral capsid;GO:0101003//ficolin-1-rich granule membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0000139//Golgi membrane;GO:0030133//transport vesicle;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0005798//Golgi-associated vesicle;GO:0005789//endoplasmic reticulum membrane;GO:0070821//tertiary granule membrane;GO:0005886//plasma membrane","GO:0005198//structural molecule activity","GO:0006886//intracellular protein transport;GO:0043312//neutrophil degranulation;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0016032//viral process;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0016192//vesicle-mediated transport","K17301//coatomer subunit beta","NP_057535.1//coatomer subunit beta [Homo sapiens]","4;1//3"]
[5480,1241,7.56,6.31,-0.260746229238524,0.328024488596491,"*",0.1966422,"PPIC","GO:0070062//extracellular exosome;GO:0005737//cytoplasm","GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0016018//cyclosporin A binding","GO:0006457//protein folding","K09563//peptidyl-prolyl isomerase C (cyclophilin C) [EC:5.2.1.8]","NP_000934.1//peptidyl-prolyl cis-trans isomerase C precursor [Homo sapiens]",4]
[88455,3917,4.54,3.79,-0.260494449119823,0.142104751886085,"*",0.0712214,"ANKRD13A","NA","NA","NA","K21437//ankyrin repeat domain-containing protein 13","XP_008002866.1//PREDICTED: ankyrin repeat domain-containing protein 13A isoform X2 [Chlorocebus sabaeus]","1//3"]
[5255,6138,8.49,7.09,-0.259978926313522,0.00592433626371106,"*",0.001940782,"PHKA1","NA","NA","NA","K07190//phosphorylase kinase alpha/beta subunit","XP_003944502.1//PREDICTED: phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform isoform X1 [Saimiri boliviensis boliviensis];XP_003944500.1//PREDICTED: phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform isoform X2 [Saimiri boliviensis boliviensis];XP_003944501.1//PREDICTED: phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform isoform X4 [Saimiri boliviensis boliviensis]","1//3;3//A2MP1"]
[26273,2162,4.93,4.12,-0.258943309194693,0.463655135275081,"*",0.313912,"FBXO3","GO:0005654//nucleoplasm;GO:0005829//cytosol","GO:0004842//ubiquitin-protein transferase activity","GO:0006508//proteolysis","K10290//F-box protein 3","XP_021541023.1//F-box only protein 3 isoform X1 [Neomonachus schauinslandi];NP_208385.1//F-box only protein 3 isoform 2 [Homo sapiens]","3//A2MP1;2//1"]
[283742,4392,4.33,3.62,-0.25837732764352,0.133992389089531,"*",0.0664258,"FAM98B","NA","NA","NA","K15434//protein FAM98B","XP_008015284.1//PREDICTED: protein FAM98B [Chlorocebus sabaeus]","3//A2MP1"]
[6767,3597,53.13,44.43,-0.257992571463067,{"v":3.30676536162362e-08,"d":"3.31E-08"},"*",{"v":4.48796e-09,"d":"4.49E-09"},"ST13","GO:0070062//extracellular exosome;GO:0043234//protein complex;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0030674//protein binding, bridging;GO:0042802//identical protein binding;GO:0051087//chaperone binding;GO:0046983//protein dimerization activity;GO:0019904//protein domain specific binding;GO:0051082//unfolded protein binding;GO:0030544//Hsp70 protein binding;GO:0032564//dATP binding;GO:0032403//protein complex binding","GO:0006457//protein folding;GO:0051260//protein homooligomerization;GO:0061084//negative regulation of protein refolding","K09560//suppressor of tumorigenicity protein 13","NP_003923.2//hsc70-interacting protein isoform 1 [Homo sapiens];NP_001265518.1//hsc70-interacting protein isoform 2 [Homo sapiens]","4;1//3"]
[9798,3915,26.11,21.85,-0.256969177924881,{"v":2.41451841992883E-6,"d":"2.41E-06"},"*",{"v":4.2474e-07,"d":"4.25E-07"},"IST1","GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0005635//nuclear envelope;GO:0005813//centrosome;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0030496//midbody;GO:0090543//Flemming body;GO:0035578//azurophil granule lumen;GO:0005829//cytosol;GO:0005576//extracellular region","GO:0090541//MIT domain binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0032403//protein complex binding;GO:0045296//cadherin binding","GO:0045184//establishment of protein localization;GO:0019076//viral release from host cell;GO:0045862//positive regulation of proteolysis;GO:0009838//abscission;GO:0000910//cytokinesis;GO:1904903//ESCRT III complex disassembly;GO:0036258//multivesicular body assembly;GO:0046745//viral capsid secondary envelopment;GO:0051301//cell division;GO:0008104//protein localization;GO:0043312//neutrophil degranulation;GO:0048672//positive regulation of collateral sprouting;GO:0015031//protein transport","K19476//vacuolar protein sorting-associated protein IST1","NP_001257904.1//IST1 homolog isoform a [Homo sapiens];NP_055576.2//IST1 homolog isoform b [Homo sapiens];NP_001257905.1//IST1 homolog isoform c [Homo sapiens];EAW59209.1//KIAA0174, isoform CRA_e [Homo sapiens]","1//3;3//A2MP1"]
[25862,7468,1.78,1.49,-0.256564910504236,0.309451314678511,"*",0.1831834,"USP49","GO:0005654//nucleoplasm","GO:0042393//histone binding;GO:0004843//thiol-dependent ubiquitin-specific protease activity;GO:0004197//cysteine-type endopeptidase activity;GO:0008270//zinc ion binding;GO:0036459//thiol-dependent ubiquitinyl hydrolase activity","GO:0006511//ubiquitin-dependent protein catabolic process;GO:0000398//mRNA splicing, via spliceosome;GO:0016579//protein deubiquitination;GO:0035616//histone H2B conserved C-terminal lysine deubiquitination","K11834//ubiquitin carboxyl-terminal hydrolase 44/49 [EC:3.4.19.12]","NP_001273483.1//ubiquitin carboxyl-terminal hydrolase 49 isoform a [Homo sapiens];NP_061031.2//ubiquitin carboxyl-terminal hydrolase 49 isoform b [Homo sapiens]","1//3;4"]
[92906,3038,7.5,6.28,-0.256126036491616,0.110905019770962,"*",0.0527448,"HNRNPLL","GO:0016020//membrane;GO:0005634//nucleus;GO:0030529//intracellular ribonucleoprotein complex;GO:0019013//viral nucleocapsid","GO:0003723//RNA binding;GO:0003729//mRNA binding","GO:0033120//positive regulation of RNA splicing;GO:0006397//mRNA processing","K13159//heterogeneous nuclear ribonucleoprotein L","NP_001136122.1//heterogeneous nuclear ribonucleoprotein L-like isoform 2 [Homo sapiens];NP_612403.2//heterogeneous nuclear ribonucleoprotein L-like isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[4594,3886,2.53,2.12,-0.255073120131111,0.319947450036684,"*",0.1910992,"MUT","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0046872//metal ion binding;GO:0004494//methylmalonyl-CoA mutase activity;GO:0031419//cobalamin binding;GO:0072341//modified amino acid binding","GO:0019626//short-chain fatty acid catabolic process;GO:0008152//metabolic process;GO:0009791//post-embryonic development;GO:0050667//homocysteine metabolic process;GO:0009235//cobalamin metabolic process","K01847//methylmalonyl-CoA mutase [EC:5.4.99.2]","NP_000246.2//methylmalonyl-CoA mutase, mitochondrial precursor [Homo sapiens]","3//A2MP1"]
[51094,2052,76.09,63.77,-0.254828981225258,{"v":1.31823420474777e-06,"d":"1.32E-06"},"*",{"v":2.22484E-7,"d":"2.22E-07"},"ADIPOR1","GO:0016020//membrane;GO:0031226//intrinsic component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0097003//adipokinetic hormone receptor activity;GO:0004872//receptor activity;GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity;GO:0042562//hormone binding;GO:0019901//protein kinase binding;GO:0055100//adiponectin binding;GO:0046872//metal ion binding","GO:0030308//negative regulation of cell growth;GO:0019395//fatty acid oxidation;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0046628//positive regulation of insulin receptor signaling pathway;GO:0046426//negative regulation of JAK-STAT cascade;GO:0010633//negative regulation of epithelial cell migration;GO:0042593//glucose homeostasis;GO:0046427//positive regulation of JAK-STAT cascade;GO:0033211//adiponectin-activated signaling pathway;GO:0042304//regulation of fatty acid biosynthetic process;GO:1901223//negative regulation of NIK/NF-kappaB signaling;GO:0019216//regulation of lipid metabolic process;GO:0010906//regulation of glucose metabolic process;GO:0033210//leptin-mediated signaling pathway;GO:0009755//hormone-mediated signaling pathway","K07297//adiponectin receptor","OWK08412.1//hypothetical protein Celaphus_00011293 [Cervus elaphus hippelaphus]","1//3;5"]
[1353,2468,27.16,22.78,-0.25371573253662,0.000520433677061611,"*",1.374878E-4,"COX11","GO:0043234//protein complex;GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion","GO:0009055//electron transfer activity;GO:0004129//cytochrome-c oxidase activity;GO:0005507//copper ion binding","GO:0055065//metal ion homeostasis;GO:0007585//respiratory gaseous exchange;GO:0008535//respiratory chain complex IV assembly;GO:0033132//negative regulation of glucokinase activity","K02258//cytochrome c oxidase assembly protein subunit 11","NP_001156333.1//cytochrome c oxidase assembly protein COX11, mitochondrial isoform 2 [Homo sapiens];NP_004366.1//cytochrome c oxidase assembly protein COX11, mitochondrial isoform 1 [Homo sapiens];NP_001308447.1//cytochrome c oxidase assembly protein COX11, mitochondrial isoform 4 [Homo sapiens];NP_001156334.1//cytochrome c oxidase assembly protein COX11, mitochondrial isoform 3 [Homo sapiens]","1//3;4;2//1"]
[79009,2575,9.46,7.94,-0.252701176196438,0.0888165704409363,"*",0.0408554,"DDX50","GO:0016020//membrane;GO:0005730//nucleolus;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0004004//ATP-dependent RNA helicase activity;GO:0005524//ATP binding;GO:0004386//helicase activity","GO:0010501//RNA secondary structure unwinding","K13183//ATP-dependent RNA helicase DDX50 [EC:3.6.4.13]","NP_076950.1//ATP-dependent RNA helicase DDX50 [Homo sapiens]","1//3"]
[9672,5121,8.66,7.27,-0.252411660807131,0.0154100756544232,"*",0.00559428,"SDC3","NA","NA","NA","K16337//syndecan 3","XP_017381434.1//PREDICTED: syndecan-3 isoform X2 [Cebus capucinus imitator]","3//A2MP1"]
[55260,2546,6.43,5.4,-0.251859330277116,0.158701319599707,"*",0.0814072,"TMEM143","GO:0016021//integral component of membrane;GO:0005739//mitochondrion","NA","NA","K19719//collagen, type II, alpha;K16628//collagen, type VII, alpha;K06236//collagen, type I, alpha;K22020//mucin-19;K19720//collagen, type III, alpha","NP_001290468.1//transmembrane protein 143 isoform c [Homo sapiens];NP_001290469.1//transmembrane protein 143 isoform d [Homo sapiens];NP_001290467.1//transmembrane protein 143 isoform b [Homo sapiens];NP_060743.2//transmembrane protein 143 isoform a [Homo sapiens]","1//3;3//A2MP1"]
[7481,1927,0.25,0.21,-0.251538766995965,0.850104312307376,"*",0.777036,"WNT11","GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005578//proteinaceous extracellular matrix","GO:0030295//protein kinase activator activity;GO:0005102//receptor binding;GO:0044212//transcription regulatory region DNA binding;GO:0005096//GTPase activator activity;GO:0005109//frizzled binding","GO:0001649//osteoblast differentiation;GO:0060412//ventricular septum morphogenesis;GO:0030335//positive regulation of cell migration;GO:0071260//cellular response to mechanical stimulus;GO:0061053//somite development;GO:0061101//neuroendocrine cell differentiation;GO:0032915//positive regulation of transforming growth factor beta2 production;GO:0003402//planar cell polarity pathway involved in axis elongation;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0060675//ureteric bud morphogenesis;GO:0043065//positive regulation of apoptotic process;GO:0072177//mesonephric duct development;GO:0001837//epithelial to mesenchymal transition;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006468//protein phosphorylation;GO:0072201//negative regulation of mesenchymal cell proliferation;GO:0043066//negative regulation of apoptotic process;GO:0010628//positive regulation of gene expression;GO:0003151//outflow tract morphogenesis;GO:0071300//cellular response to retinoic acid;GO:0060070//canonical Wnt signaling pathway;GO:0070830//bicellular tight junction assembly;GO:0061037//negative regulation of cartilage development;GO:0030325//adrenal gland development;GO:0016055//Wnt signaling pathway;GO:0048706//embryonic skeletal system development;GO:0060197//cloacal septation;GO:0034394//protein localization to cell surface;GO:0060775//planar cell polarity pathway involved in gastrula mediolateral intercalation;GO:0043547//positive regulation of GTPase activity;GO:0045893//positive regulation of transcription, DNA-templated;GO:0007223//Wnt signaling pathway, calcium modulating pathway;GO:0060484//lung-associated mesenchyme development;GO:0048341//paraxial mesoderm formation;GO:0060021//palate development;GO:0090037//positive regulation of protein kinase C signaling;GO:0060028//convergent extension involved in axis elongation;GO:0045165//cell fate commitment;GO:0030308//negative regulation of cell growth;GO:0030282//bone mineralization;GO:0030182//neuron differentiation;GO:0030336//negative regulation of cell migration;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0051496//positive regulation of stress fiber assembly;GO:0048844//artery morphogenesis;GO:0090272//negative regulation of fibroblast growth factor production;GO:0031667//response to nutrient levels;GO:0048570//notochord morphogenesis;GO:0060548//negative regulation of cell death;GO:0045199//maintenance of epithelial cell apical/basal polarity","K01384//wingless-type MMTV integration site family, member 11","XP_020747150.1//protein Wnt-11 [Odocoileus virginianus texanus]","2//1"]
[111,5123,0.25,0.21,-0.251538766995965,0.922338165381547,"*",0.86864,"ADCY5","GO:0005929//cilium;GO:0045111//intermediate filament cytoskeleton;GO:0005622//intracellular;GO:0016021//integral component of membrane;GO:0008074//guanylate cyclase complex, soluble;GO:0005886//plasma membrane","GO:0005524//ATP binding;GO:0046982//protein heterodimerization activity;GO:0008179//adenylate cyclase binding;GO:0097110//scaffold protein binding;GO:0046872//metal ion binding;GO:0004016//adenylate cyclase activity;GO:0000166//nucleotide binding;GO:0004383//guanylate cyclase activity","GO:1904322//cellular response to forskolin;GO:0035556//intracellular signal transduction;GO:0001973//adenosine receptor signaling pathway;GO:0007195//adenylate cyclase-inhibiting dopamine receptor signaling pathway;GO:0061178//regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0007191//adenylate cyclase-activating dopamine receptor signaling pathway;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0071377//cellular response to glucagon stimulus;GO:0006171//cAMP biosynthetic process;GO:0006182//cGMP biosynthetic process;GO:0007190//activation of adenylate cyclase activity;GO:0007626//locomotory behavior;GO:0034199//activation of protein kinase A activity;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0050885//neuromuscular process controlling balance;GO:0003091//renal water homeostasis","K08045//adenylate cyclase 5 [EC:4.6.1.1]","NP_899200.1//adenylate cyclase type 5 isoform 1 [Homo sapiens];NP_001186571.1//adenylate cyclase type 5 isoform 2 [Homo sapiens]","1//3;2//1"]
[9289,3797,48.95,41.14,-0.250767065966124,{"v":9.77219020479303e-08,"d":"9.77E-08"},"*",{"v":1.40398e-08,"d":"1.40E-08"},"ADGRG1","GO:0070062//extracellular exosome;GO:0045121//membrane raft;GO:0005887//integral component of plasma membrane;GO:0097451//glial limiting end-foot;GO:0005622//intracellular;GO:0016021//integral component of membrane","GO:0005518//collagen binding;GO:0008201//heparin binding;GO:0050840//extracellular matrix binding;GO:0004930//G-protein coupled receptor activity","GO:0016477//cell migration;GO:0045785//positive regulation of cell adhesion;GO:0021801//cerebral cortex radial glia guided migration;GO:0007166//cell surface receptor signaling pathway;GO:0007420//brain development;GO:0010573//vascular endothelial growth factor production;GO:0021819//layer formation in cerebral cortex;GO:0008285//negative regulation of cell proliferation;GO:0007186//G-protein coupled receptor signaling pathway;GO:0001525//angiogenesis;GO:0021796//cerebral cortex regionalization;GO:0070528//protein kinase C signaling;GO:0007267//cell-cell signaling;GO:2000179//positive regulation of neural precursor cell proliferation;GO:0007266//Rho protein signal transduction;GO:0007155//cell adhesion;GO:2001223//negative regulation of neuron migration;GO:0035025//positive regulation of Rho protein signal transduction;GO:0072520//seminiferous tubule development","K08450//G protein-coupled receptor 56","NP_005673.3//adhesion G-protein coupled receptor G1 isoform a precursor [Homo sapiens];NP_958933.1//adhesion G-protein coupled receptor G1 isoform b precursor [Homo sapiens];NP_001277071.1//adhesion G-protein coupled receptor G1 isoform d precursor [Homo sapiens];NP_001139245.1//adhesion G-protein coupled receptor G1 isoform c precursor [Homo sapiens]","6;1//3;3//A2MP1;2//1"]
[23212,1724,43.2,36.32,-0.250267109759916,0.00146387037175043,"*",0.000423014,"RRS1","GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005730//nucleolus;GO:0000794//condensed nuclear chromosome;GO:0001650//fibrillar center;GO:0030687//preribosome, large subunit precursor","GO:0003723//RNA binding;GO:0008097//5S rRNA binding","GO:0002244//hematopoietic progenitor cell differentiation;GO:0000027//ribosomal large subunit assembly;GO:0000447//endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:1901796//regulation of signal transduction by p53 class mediator;GO:0000055//ribosomal large subunit export from nucleus;GO:0042254//ribosome biogenesis;GO:0007080//mitotic metaphase plate congression;GO:0042273//ribosomal large subunit biogenesis;GO:1902570//protein localization to nucleolus","K14852//regulator of ribosome biosynthesis","NP_055984.1//ribosome biogenesis regulatory protein homolog [Homo sapiens]","3//A2MP1"]
[285237,2782,7.36,6.19,-0.249766356842748,0.127964891202873,"*",0.0624684,"C3orf38","GO:0005634//nucleus","NA","GO:0043065//positive regulation of apoptotic process;GO:0006915//apoptotic process","K09291//nucleoprotein TPR;K12396//AP-3 complex subunit delta","NP_776185.2//uncharacterized protein C3orf38 [Homo sapiens]","3//A2MP1"]
[50624,2279,0.63,0.53,-0.249359468936717,0.724668135004822,"*",0.611572,"CUZD1","GO:0042589//zymogen granule membrane;GO:0030658//transport vesicle membrane;GO:0016021//integral component of membrane","NA","GO:0006931//substrate-dependent cell migration, cell attachment to substrate;GO:0008283//cell proliferation;GO:0051301//cell division;GO:0032023//trypsinogen activation;GO:0007049//cell cycle","K13912//deleted in malignant brain tumors 1 protein","NP_071317.2//CUB and zona pellucida-like domain-containing protein 1 precursor [Homo sapiens]",5]
[148156,3577,1.83,1.54,-0.248913297589141,0.491066475306958,"*",0.338004,"ZNF558","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","XP_020834727.1//LOW QUALITY PROTEIN: zinc finger protein 420-like [Phascolarctos cinereus]","1//3;2//1"]
[342926,3615,2.91,2.45,-0.248237403905713,0.33886860594757,"*",0.204734,"ZNF677","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","XP_019663848.1//PREDICTED: zinc finger protein 677-like isoform X1 [Ailuropoda melanoleuca]","1//3;3//A2MP1"]
[83698,9500,0.19,0.16,-0.247927513443586,0.666494147622319,"*",0.546622,"CALN1","GO:0032588//trans-Golgi network membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0048471//perinuclear region of cytoplasm","GO:0005509//calcium ion binding","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K02183//calmodulin","EDL19465.1//calneuron 1, isoform CRA_c, partial [Mus musculus];NP_113656.2//calcium-binding protein 8 isoform 1 [Homo sapiens]","3//A2MP1;2//1"]
[27154,6054,7.49,6.31,-0.247325713476202,0.0169483350690066,"*",6.22698E-3,"BRPF3","GO:0005829//cytosol;GO:0005576//extracellular region;GO:0070776//MOZ/MORF histone acetyltransferase complex","GO:0046872//metal ion binding","GO:0002576//platelet degranulation;GO:0043966//histone H3 acetylation","K11350//bromodomain and PHD finger-containing protein 3","NP_056510.2//bromodomain and PHD finger-containing protein 3 [Homo sapiens]","2//1"]
[9942,3083,4.84,4.08,-0.246437895303099,0.24729608164985,"*",0.1396246,"XYLB","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0004856//xylulokinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016773//phosphotransferase activity, alcohol group as acceptor","GO:0019640//glucuronate catabolic process to xylulose 5-phosphate;GO:0005997//xylulose metabolic process;GO:0006091//generation of precursor metabolites and energy;GO:0005975//carbohydrate metabolic process;GO:0042732//D-xylose metabolic process;GO:0005998//xylulose catabolic process","K00854//xylulokinase [EC:2.7.1.17]","EAW64532.1//xylulokinase homolog (H. influenzae), isoform CRA_b [Homo sapiens];NP_005099.2//xylulose kinase isoform 2 [Homo sapiens];XP_011532627.1//PREDICTED: xylulose kinase isoform X1 [Homo sapiens];NP_001336109.1//xylulose kinase isoform 4 [Homo sapiens]","1//3;3//A2MP1"]
[284656,2095,3.51,2.96,-0.245873854675611,0.377957280610197,"*",0.235756,"EPHA10","GO:0070062//extracellular exosome;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005524//ATP binding;GO:0005003//ephrin receptor activity;GO:0005005//transmembrane-ephrin receptor activity","GO:0048013//ephrin receptor signaling pathway","K08897//Eph receptor A10 [EC:2.7.10.1]","NP_775912.2//ephrin type-A receptor 10 isoform 2 precursor [Homo sapiens];NP_001092909.1//ephrin type-A receptor 10 isoform 3 precursor [Homo sapiens]","1//3;2//1"]
[23395,4203,5.56,4.69,-0.245496960208131,0.108377446153846,"*",0.0513324,"LARS2","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0004823//leucine-tRNA ligase activity;GO:0005524//ATP binding;GO:0002161//aminoacyl-tRNA editing activity","GO:0006418//tRNA aminoacylation for protein translation;GO:0032543//mitochondrial translation;GO:0006429//leucyl-tRNA aminoacylation","K01869//leucyl-tRNA synthetase [EC:6.1.1.4]","NP_056155.1//probable leucine--tRNA ligase, mitochondrial [Homo sapiens]","3//A2MP1"]
[84959,6917,16.07,13.56,-0.24501275053875,{"v":8.6318636254805e-05,"d":"8.63E-05"},"*",{"v":1.968026e-05,"d":"1.97E-05"},"UBASH3B","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0042802//identical protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0004725//protein tyrosine phosphatase activity;GO:0051219//phosphoprotein binding","GO:0045671//negative regulation of osteoclast differentiation;GO:0043393//regulation of protein binding;GO:0051279//regulation of release of sequestered calcium ion into cytosol;GO:0009968//negative regulation of signal transduction;GO:0045779//negative regulation of bone resorption;GO:0038063//collagen-activated tyrosine kinase receptor signaling pathway;GO:0006469//negative regulation of protein kinase activity;GO:0070527//platelet aggregation;GO:0090331//negative regulation of platelet aggregation","K18993//ubiquitin-associated and SH3 domain-containing protein [EC:3.1.3.48]","NP_116262.2//ubiquitin-associated and SH3 domain-containing protein B [Homo sapiens]",4]
[4175,3791,28.36,23.94,-0.244434380296014,1.27200464804469E-4,"*",{"v":2.99328e-05,"d":"2.99E-05"},"MCM6","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000784//nuclear chromosome, telomeric region;GO:0042555//MCM complex","GO:0003677//DNA binding;GO:0003697//single-stranded DNA binding;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0003678//DNA helicase activity;GO:0004003//ATP-dependent DNA helicase activity","GO:0006260//DNA replication;GO:0000082//G1/S transition of mitotic cell cycle;GO:0006268//DNA unwinding involved in DNA replication;GO:0006270//DNA replication initiation","K02542//DNA replication licensing factor MCM6 [EC:3.6.4.12]","NP_005906.2//DNA replication licensing factor MCM6 [Homo sapiens]",5]
[6924,4959,8.93,7.54,-0.244095651852559,0.0198829223509768,"*",7.45454E-3,"ELOA","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005615//extracellular space;GO:0016021//integral component of membrane;GO:0070449//elongin complex","GO:0003746//translation elongation factor activity","GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006355//regulation of transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter","K15076//transcription elongation factor B, polypeptide 3","NP_003189.2//elongin-A [Homo sapiens]","2//1"]
[54600,2395,53.34,45.08,-0.242730309378705,{"v":3.20322367901235E-5,"d":"3.20E-05"},"*",{"v":6.82194e-06,"d":"6.82E-06"},"UGT1A9","GO:0070062//extracellular exosome;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0046982//protein heterodimerization activity;GO:0015020//glucuronosyltransferase activity;GO:0042803//protein homodimerization activity;GO:0008144//drug binding;GO:0004857//enzyme inhibitor activity;GO:0005504//fatty acid binding;GO:0005496//steroid binding;GO:0019899//enzyme binding;GO:0001972//retinoic acid binding","GO:0045939//negative regulation of steroid metabolic process;GO:2001030//negative regulation of cellular glucuronidation;GO:0008152//metabolic process;GO:0052697//xenobiotic glucuronidation;GO:0006805//xenobiotic metabolic process;GO:0017144//drug metabolic process;GO:0008202//steroid metabolic process;GO:0042573//retinoic acid metabolic process;GO:0052695//cellular glucuronidation;GO:0009804//coumarin metabolic process;GO:0006631//fatty acid metabolic process;GO:0045922//negative regulation of fatty acid metabolic process;GO:0019216//regulation of lipid metabolic process;GO:1904224//negative regulation of glucuronosyltransferase activity;GO:0051552//flavone metabolic process;GO:0052696//flavonoid glucuronidation","K00699//glucuronosyltransferase [EC:2.4.1.17]","NP_066307.1//UDP-glucuronosyltransferase 1-9 precursor [Homo sapiens]","2//1"]
[9869,4095,8.21,6.94,-0.242446559199544,0.0920562077225308,"*",0.0425358,"SETDB1","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005694//chromosome;GO:0005886//plasma membrane","GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0008270//zinc ion binding;GO:1990841//promoter-specific chromatin binding;GO:0018024//histone-lysine N-methyltransferase activity","GO:0006351//transcription, DNA-templated;GO:0090309//positive regulation of methylation-dependent chromatin silencing;GO:0033273//response to vitamin;GO:0007265//Ras protein signal transduction;GO:0045471//response to ethanol","K11421//histone-lysine N-methyltransferase SETDB1 [EC:2.1.1.43]","NP_036564.3//histone-lysine N-methyltransferase SETDB1 isoform 2 [Homo sapiens];XP_008968703.1//PREDICTED: histone-lysine N-methyltransferase SETDB1 isoform X2 [Pan paniscus];NP_001230420.1//histone-lysine N-methyltransferase SETDB1 isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[148252,3412,2.59,2.19,-0.242021228085381,0.385641589292849,"*",0.241708,"DIRAS1","NA","NA","NA","K07840//DIRAS family, GTP-binding Ras-like 1","XP_010347728.1//PREDICTED: GTP-binding protein Di-Ras1 [Saimiri boliviensis boliviensis]","3//A2MP1"]
[5154,2762,6.5,5.5,-0.241008099503795,0.172735241803279,"*",0.089709,"PDGFA","NA","NA","NA","K04359//platelet-derived growth factor subunit A","XP_011513718.1//PREDICTED: platelet-derived growth factor subunit A isoform X2 [Homo sapiens];XP_011513720.1//PREDICTED: platelet-derived growth factor subunit A isoform X4 [Homo sapiens]","4;5"]
[11011,5592,8,6.77,-0.240844166199728,3.37446662733293E-3,"*",1.052646E-3,"TLK2","GO:0005634//nucleus;GO:0005882//intermediate filament;GO:0048471//perinuclear region of cytoplasm","GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding","GO:0007059//chromosome segregation;GO:0006468//protein phosphorylation;GO:0001672//regulation of chromatin assembly or disassembly;GO:0035556//intracellular signal transduction;GO:0071480//cellular response to gamma radiation;GO:0018105//peptidyl-serine phosphorylation;GO:0016569//covalent chromatin modification;GO:0010507//negative regulation of autophagy;GO:0007049//cell cycle;GO:0006974//cellular response to DNA damage stimulus;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process","K08864//tousled-like kinase [EC:2.7.11.1]","AAH44925.2//TLK2 protein, partial [Homo sapiens];XP_016879534.1//PREDICTED: serine/threonine-protein kinase tousled-like 2 isoform X5 [Homo sapiens]","1//3;3//A2MP1"]
[147670,2542,2.61,2.21,-0.240003437178453,0.491111142077497,"*",0.338004,"SMIM17","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein;K12581//CCR4-NOT transcription complex subunit 7/8;K01064//wingless-type MMTV integration site family, member 9","XP_007996458.1//PREDICTED: small integral membrane protein 17 isoform X1 [Chlorocebus sabaeus]","1//3"]
[23155,4402,11.84,10.03,-0.239347475016769,0.0143223067385632,"*",0.00515456,"CLCC1","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0034707//chloride channel complex","GO:0005254//chloride channel activity","NA","K22188//chloride channel CLIC-like protein 1","NP_001265131.1//chloride channel CLIC-like protein 1 isoform 3 precursor [Homo sapiens];NP_001265132.1//chloride channel CLIC-like protein 1 isoform 4 precursor [Homo sapiens];NP_055942.1//chloride channel CLIC-like protein 1 isoform 2 precursor [Homo sapiens];NP_001041675.1//chloride channel CLIC-like protein 1 isoform 1 precursor [Homo sapiens]","1//3;4;2//1"]
[64081,2386,1.44,1.22,-0.239187663879426,0.345667803610108,"*",0.209794,"PBLD","GO:0070062//extracellular exosome;GO:0005737//cytoplasm","GO:0016853//isomerase activity;GO:0042802//identical protein binding;GO:0003824//catalytic activity","GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0010633//negative regulation of epithelial cell migration;GO:0060392//negative regulation of SMAD protein import into nucleus;GO:0009058//biosynthetic process;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0050680//negative regulation of epithelial cell proliferation;GO:0060394//negative regulation of pathway-restricted SMAD protein phosphorylation;GO:0030277//maintenance of gastrointestinal epithelium","K01368//cathepsin S [EC:3.4.22.27];K17985//activating molecule in BECN1-regulated autophagy protein 1","XP_007961461.1//PREDICTED: phenazine biosynthesis-like domain-containing protein isoform X2 [Chlorocebus sabaeus];NP_001028255.1//phenazine biosynthesis-like domain-containing protein isoform b [Homo sapiens]","1//3;3//A2MP1"]
[84946,1928,19.03,16.13,-0.238529123118379,0.0414086117753897,"*",0.017127,"LTV1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0034448//EGO complex;GO:0005829//cytosol;GO:0030688//preribosome, small subunit precursor;GO:0031902//late endosome membrane","NA","GO:0000056//ribosomal small subunit export from nucleus;GO:0042274//ribosomal small subunit biogenesis;GO:0006364//rRNA processing","K14798//protein LTV1","NP_116249.2//protein LTV1 homolog isoform 1 [Homo sapiens];NP_001316882.1//protein LTV1 homolog isoform 2 [Homo sapiens]","1//3;4"]
[79658,3073,3.88,3.29,-0.237969068451886,0.295537656016286,"*",0.1726714,"ARHGAP10","GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0048471//perinuclear region of cytoplasm","GO:0005096//GTPase activator activity","GO:0007165//signal transduction;GO:0007010//cytoskeleton organization;GO:0043066//negative regulation of apoptotic process;GO:0051056//regulation of small GTPase mediated signal transduction","K13736//Rho GTPase-activating protein 10","NP_078881.3//rho GTPase-activating protein 10 [Homo sapiens]","3//A2MP1"]
[23119,6812,1.45,1.23,-0.237394584675695,0.356051837345078,"*",0.217612,"HIC2","NA","GO:0003676//nucleic acid binding","NA","K09228//KRAB domain-containing zinc finger protein","XP_004063137.2//PREDICTED: hypermethylated in cancer 2 protein [Gorilla gorilla gorilla]","2//1"]
[9687,7622,2.71,2.3,-0.236658990409496,0.00972413257225959,"*",0.00334872,"GREB1","GO:0070062//extracellular exosome;GO:0016021//integral component of membrane","NA","NA","K10955//mucin-2","NP_149081.1//protein GREB1 isoform b [Homo sapiens];NP_055483.2//protein GREB1 isoform a [Homo sapiens];XP_016802839.1//PREDICTED: protein GREB1 isoform X8 [Pan troglodytes]","3//A2MP1;2//1"]
[83445,2391,1.92,1.63,-0.236234346490079,0.497068950602737,"*",0.343318,"GSG1","GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0070063//RNA polymerase binding","NA","K11167//dehydrogenase/reductase SDR family member 7C [EC:1.1.-.-];K11290//template-activating factor I","EAW96301.1//germ cell associated 1, isoform CRA_c [Homo sapiens];NP_001193774.1//germ cell-specific gene 1 protein isoform 7 [Homo sapiens];NP_001193772.1//germ cell-specific gene 1 protein isoform 6 [Homo sapiens];NP_722545.2//germ cell-specific gene 1 protein isoform 2 [Homo sapiens];NP_001193771.1//germ cell-specific gene 1 protein isoform 5 [Homo sapiens];NP_112579.2//germ cell-specific gene 1 protein isoform 1 [Homo sapiens];NP_001074024.1//germ cell-specific gene 1 protein isoform 4 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[9429,4292,16.16,13.73,-0.235095572604694,0.00223560663522538,"*",0.000670654,"ABCG2","GO:0005634//nucleus;GO:0016324//apical plasma membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0005886//plasma membrane;GO:0043235//receptor complex","GO:0015232//heme transporter activity;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0042626//ATPase activity, coupled to transmembrane movement of substances;GO:0008559//xenobiotic transmembrane transporting ATPase activity;GO:0042803//protein homodimerization activity;GO:0005215//transporter activity","GO:0006810//transport;GO:0006879//cellular iron ion homeostasis;GO:0042493//response to drug;GO:0033344//cholesterol efflux;GO:0046415//urate metabolic process","K05681//ATP-binding cassette, subfamily G (WHITE), member 2","NP_001335916.1//ATP-binding cassette sub-family G member 2 isoform 3 [Homo sapiens];NP_001244315.1//ATP-binding cassette sub-family G member 2 isoform 2 [Homo sapiens];NP_004818.2//ATP-binding cassette sub-family G member 2 isoform 1 [Homo sapiens]","1//3;2//1"]
[23463,4815,29.2,24.81,-0.235046633874949,{"v":2.18870512374582e-05,"d":"2.19E-05"},"*",{"v":4.50648e-06,"d":"4.51E-06"},"ICMT","GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0004671//protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity;GO:0003880//protein C-terminal carboxyl O-methyltransferase activity","GO:0043687//post-translational protein modification;GO:0006612//protein targeting to membrane;GO:0006464//cellular protein modification process;GO:0006481//C-terminal protein methylation","K00587//protein-S-isoprenylcysteine O-methyltransferase [EC:2.1.1.100]","NP_036537.1//protein-S-isoprenylcysteine O-methyltransferase [Homo sapiens]","3//A2MP1"]
[26577,2047,10.19,8.66,-0.234715121439089,0.154869309937508,"*",0.0791216,"PCOLCE2","GO:0070062//extracellular exosome","GO:0016504//peptidase activator activity;GO:0005518//collagen binding;GO:0008201//heparin binding","GO:1990830//cellular response to leukemia inhibitory factor","K14616//cubilin","NP_037495.1//procollagen C-endopeptidase enhancer 2 precursor [Homo sapiens]","3//A2MP1"]
[56658,3481,2.4,2.04,-0.234465253637023,0.428240891209417,"*",0.282402,"TRIM39","GO:0005829//cytosol;GO:0005622//intracellular;GO:0005739//mitochondrion","GO:0042802//identical protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0016874//ligase activity","GO:2001235//positive regulation of apoptotic signaling pathway;GO:0016567//protein ubiquitination;GO:2000059//negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0006915//apoptotic process","K12015//tripartite motif-containing protein 39 [EC:2.3.2.27]","NP_742013.1//E3 ubiquitin-protein ligase TRIM39 isoform 2 [Homo sapiens];NP_067076.2//E3 ubiquitin-protein ligase TRIM39 isoform 1 [Homo sapiens]","3//A2MP1;2//1"]
[9070,2874,14.11,12,-0.233683582101383,0.0305802136283186,"*",0.01211416,"ASH2L","GO:0048188//Set1C/COMPASS complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0071339//MLL1 complex;GO:0035097//histone methyltransferase complex;GO:0005719//nuclear euchromatin;GO:0044666//MLL3/4 complex","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0008168//methyltransferase activity;GO:0042800//histone methyltransferase activity (H3-K4 specific);GO:0044212//transcription regulatory region DNA binding;GO:1990188//euchromatin binding;GO:0018024//histone-lysine N-methyltransferase activity;GO:0008013//beta-catenin binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0051568//histone H3-K4 methylation;GO:0043627//response to estrogen;GO:0045652//regulation of megakaryocyte differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:1904837//beta-catenin-TCF complex assembly;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006974//cellular response to DNA damage stimulus;GO:0030097//hemopoiesis;GO:0008284//positive regulation of cell proliferation","K14964//Set1/Ash2 histone methyltransferase complex subunit ASH2","NP_004665.2//set1/Ash2 histone methyltransferase complex subunit ASH2 isoform a [Homo sapiens];XP_008954402.1//PREDICTED: set1/Ash2 histone methyltransferase complex subunit ASH2 isoform X2 [Pan paniscus];NP_001098684.1//set1/Ash2 histone methyltransferase complex subunit ASH2 isoform b [Homo sapiens];XP_003269625.1//PREDICTED: set1/Ash2 histone methyltransferase complex subunit ASH2 isoform X1 [Nomascus leucogenys]","4;1//3;2//1"]
[201780,2118,4.09,3.48,-0.23301353709302,0.407426983533943,"*",0.264876,"SLC10A4","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0008508//bile acid:sodium symporter activity","GO:0015721//bile acid and bile salt transport","K14344//solute carrier family 10 (sodium/bile acid cotransporter), member 4","NP_689892.1//sodium/bile acid cotransporter 4 [Homo sapiens]","3//A2MP1"]
[162239,3342,3.63,3.09,-0.232362710091376,0.226262762962963,"*",0.1246754,"ZFP1","GO:0005654//nucleoplasm;GO:0005813//centrosome","GO:0046872//metal ion binding;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","XP_013846339.1//zinc finger protein 182 isoform X3 [Sus scrofa];XP_008690954.1//PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 28 homolog [Ursus maritimus]","1//3;3//A2MP1"]
[51101,3352,2.56,2.18,-0.231815675223074,0.407387755054882,"*",0.264876,"ZC2HC1A","NA","GO:0046872//metal ion binding","NA","K00234//succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1]","NP_057094.2//zinc finger C2HC domain-containing protein 1A [Homo sapiens]","2//1"]
[26112,3416,3.17,2.7,-0.231523433088576,0.351657888980263,"*",0.214156,"CCDC69","GO:0051233//spindle midzone;GO:0005737//cytoplasm;GO:0030496//midbody","NA","GO:0051255//spindle midzone assembly","K17985//activating molecule in BECN1-regulated autophagy protein 1;K01064//wingless-type MMTV integration site family, member 9","NP_056436.2//coiled-coil domain-containing protein 69 [Homo sapiens]","2//1"]
[146664,4195,53.18,45.31,-0.231054286344278,{"v":1.56762256475584E-7,"d":"1.57E-07"},"*",{"v":2.3111e-08,"d":"2.31E-08"},"MGAT5B","GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0046872//metal ion binding;GO:0030144//alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity","GO:0006487//protein N-linked glycosylation","K09661//mannosyl alpha-1,6-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B [EC:2.4.1.-]","NP_653278.2//alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B isoform 1 [Homo sapiens];NP_001186101.1//alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B isoform 3 [Homo sapiens];NP_945193.1//alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B isoform 2 [Homo sapiens]","1//3;2//1"]
[5451,13905,1.96,1.67,-0.231005551641156,0.10786750448472,"*",0.0510436,"POU2F1","GO:0090575//RNA polymerase II transcription factor complex;GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005783//endoplasmic reticulum","GO:0003677//DNA binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0000983//transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0042795//snRNA transcription from RNA polymerase II promoter;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated","K09364//POU domain transcription factor, class 2","XP_011946498.1//PREDICTED: POU domain, class 2, transcription factor 1 isoform X1 [Cercocebus atys];XP_004425133.2//PREDICTED: POU domain, class 2, transcription factor 1 isoform X1 [Ceratotherium simum simum];XP_012513230.1//PREDICTED: POU domain, class 2, transcription factor 1 isoform X3 [Propithecus coquereli]","1//3;3//A2MP1"]
[7430,3138,82.53,70.34,-0.23057330541206,{"v":7.49911504771472e-09,"d":"7.50E-09"},"*",{"v":9.3469e-10,"d":"9.35E-10"},"EZR","GO:0005884//actin filament;GO:0016324//apical plasma membrane;GO:0015629//actin cytoskeleton;GO:0045177//apical part of cell","GO:0051015//actin filament binding;GO:0003779//actin binding;GO:0051117//ATPase binding;GO:0045296//cadherin binding","GO:0031532//actin cytoskeleton reorganization;GO:0051017//actin filament bundle assembly;GO:0030953//astral microtubule organization;GO:0007411//axon guidance","K08007//villin 2 (ezrin)","NP_003370.2//ezrin [Homo sapiens]","1//3;4"]
[57478,10698,2.66,2.27,-0.228733948210275,0.0936487628988643,"*",0.0433596,"USP31","GO:0005634//nucleus","GO:0004843//thiol-dependent ubiquitin-specific protease activity","GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination","K11852//ubiquitin carboxyl-terminal hydrolase 31 [EC:3.4.19.12]","NP_065769.3//ubiquitin carboxyl-terminal hydrolase 31 [Homo sapiens]","3//A2MP1"]
[2653,1538,36.29,30.97,-0.228700673804671,0.0146213646911867,"*",0.00527592,"GCSH","GO:0005759//mitochondrial matrix;GO:0005960//glycine cleavage complex;GO:0005739//mitochondrion","GO:0004047//aminomethyltransferase activity","GO:0019464//glycine decarboxylation via glycine cleavage system;GO:0006546//glycine catabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0009249//protein lipoylation","K02437//glycine cleavage system H protein","NP_004474.2//glycine cleavage system H protein, mitochondrial precursor [Homo sapiens]",4]
[23765,8592,3.01,2.57,-0.227995127565824,0.124173126121236,"*",0.0601432,"IL17RA","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0030368//interleukin-17 receptor activity;GO:0005102//receptor binding","GO:0050832//defense response to fungus;GO:0072537//fibroblast activation;GO:0032747//positive regulation of interleukin-23 production;GO:2000667//positive regulation of interleukin-13 secretion;GO:0071621//granulocyte chemotaxis;GO:0007166//cell surface receptor signaling pathway;GO:0097398//cellular response to interleukin-17;GO:2000664//positive regulation of interleukin-5 secretion;GO:1900017//positive regulation of cytokine production involved in inflammatory response","K05164//interleukin 17 receptor A","NP_055154.3//interleukin-17 receptor A isoform 1 precursor [Homo sapiens];NP_001276834.1//interleukin-17 receptor A isoform 2 precursor [Homo sapiens]","6;1//3"]
[65082,4069,13.97,11.93,-0.227737977714235,0.0522678848920863,"*",0.022286,"VPS33A","GO:0005765//lysosomal membrane;GO:0005770//late endosome;GO:0030136//clathrin-coated vesicle;GO:0031902//late endosome membrane;GO:0005764//lysosome;GO:0048471//perinuclear region of cytoplasm;GO:0030897//HOPS complex;GO:0005776//autophagosome;GO:0005769//early endosome;GO:0033263//CORVET complex","NA","GO:0035751//regulation of lysosomal lumen pH;GO:0006904//vesicle docking involved in exocytosis;GO:0016192//vesicle-mediated transport;GO:0032400//melanosome localization;GO:0048070//regulation of developmental pigmentation;GO:0043473//pigmentation;GO:0097352//autophagosome maturation;GO:0030220//platelet formation;GO:0008333//endosome to lysosome transport;GO:0032418//lysosome localization;GO:0015031//protein transport","K20182//vacuolar protein sorting-associated protein 33","XP_018894523.1//PREDICTED: vacuolar protein sorting-associated protein 33A isoform X2 [Gorilla gorilla gorilla];NP_001337950.1//vacuolar protein sorting-associated protein 33A isoform 5 [Homo sapiens];NP_001337947.1//vacuolar protein sorting-associated protein 33A isoform 2 [Homo sapiens];NP_075067.2//vacuolar protein sorting-associated protein 33A isoform 1 [Homo sapiens];NP_001337949.1//vacuolar protein sorting-associated protein 33A isoform 4 [Homo sapiens]","1//3;5"]
[153769,3043,3.43,2.93,-0.227307911750565,0.369891140695915,"*",0.22959,"SH3RF2","GO:0005654//nucleoplasm","GO:0004864//protein phosphatase inhibitor activity;GO:0046872//metal ion binding;GO:0019902//phosphatase binding;GO:0016740//transferase activity;GO:0008157//protein phosphatase 1 binding","GO:0016567//protein ubiquitination;GO:0010923//negative regulation of phosphatase activity","K12171//E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27]","NP_689763.3//putative E3 ubiquitin-protein ligase SH3RF2 [Homo sapiens]","3//A2MP1"]
[1389,3823,9.44,8.07,-0.226218186084061,0.0576746937744885,"*",0.0248802,"CREBL2","GO:0005634//nucleus","GO:0003677//DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0007165//signal transduction;GO:0030154//cell differentiation;GO:0045600//positive regulation of fat cell differentiation;GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046326//positive regulation of glucose import;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0007049//cell cycle;GO:0050821//protein stabilization;GO:0046889//positive regulation of lipid biosynthetic process","NA","XP_011239631.1//PREDICTED: cAMP-responsive element-binding protein-like 2 isoform X1 [Mus musculus]","3//A2MP1"]
[790,7013,30.45,26.04,-0.225712779628059,{"v":2.32273596688742e-07,"d":"2.32E-07"},"*",{"v":3.51304e-08,"d":"3.51E-08"},"CAD","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0042995//cell projection;GO:0016363//nuclear matrix;GO:0005737//cytoplasm;GO:0043195//terminal bouton;GO:0043025//neuronal cell body;GO:0005829//cytosol","GO:0004087//carbamoyl-phosphate synthase (ammonia) activity;GO:0016597//amino acid binding;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0004070//aspartate carbamoyltransferase activity;GO:0004088//carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity;GO:0070335//aspartate binding;GO:0046872//metal ion binding;GO:0016812//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides;GO:0004672//protein kinase activity;GO:0008270//zinc ion binding;GO:0004151//dihydroorotase activity;GO:0019899//enzyme binding","GO:0046134//pyrimidine nucleoside biosynthetic process;GO:0006526//arginine biosynthetic process;GO:0017144//drug metabolic process;GO:0046777//protein autophosphorylation;GO:0006541//glutamine metabolic process;GO:0018107//peptidyl-threonine phosphorylation;GO:0044205//'de novo' UMP biosynthetic process;GO:0000050//urea cycle;GO:0006207//'de novo' pyrimidine nucleobase biosynthetic process","K11540//carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:6.3.5.5 2.1.3.2 3.5.2.3]","NP_001293008.1//CAD protein isoform 2 [Homo sapiens];NP_004332.2//CAD protein isoform 1 [Homo sapiens]","4;1//3"]
[27072,4894,6.01,5.14,-0.225596631517307,0.0972265098777046,"*",0.04529,"VPS41","GO:0016020//membrane;GO:0005765//lysosomal membrane;GO:0010008//endosome membrane;GO:0005770//late endosome;GO:0015630//microtubule cytoskeleton;GO:0030136//clathrin-coated vesicle;GO:0031902//late endosome membrane;GO:0030897//HOPS complex;GO:0005829//cytosol;GO:0005798//Golgi-associated vesicle;GO:0030123//AP-3 adaptor complex;GO:0071439//clathrin complex;GO:0005769//early endosome;GO:0033263//CORVET complex","GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0051020//GTPase binding;GO:0043621//protein self-association;GO:0008017//microtubule binding","GO:0045055//regulated exocytosis;GO:0042144//vacuole fusion, non-autophagic;GO:0006886//intracellular protein transport;GO:0048193//Golgi vesicle transport;GO:0006623//protein targeting to vacuole;GO:0006914//autophagy;GO:0008333//endosome to lysosome transport;GO:1902774//late endosome to lysosome transport;GO:0034058//endosomal vesicle fusion;GO:0035542//regulation of SNARE complex assembly","K20184//vacuolar protein sorting-associated protein 41","NP_055211.2//vacuolar protein sorting-associated protein 41 homolog isoform 1 [Homo sapiens];NP_542198.2//vacuolar protein sorting-associated protein 41 homolog isoform 2 [Homo sapiens]","3//A2MP1"]
[125965,1679,7.34,6.28,-0.225015503951586,0.327767325882599,"*",0.196447,"COX6B2","GO:0005758//mitochondrial intermembrane space;GO:0030061//mitochondrial crista","NA","NA","K02267//cytochrome c oxidase subunit 6b","EAW72367.1//cytochrome c oxidase subunit VIb polypeptide 2 (testis), isoform CRA_a, partial [Homo sapiens]",4]
[79707,6728,9.65,8.26,-0.224387160735997,0.00781119991079725,"*",0.00263128,"NOL9","GO:0016020//membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0045111//intermediate filament cytoskeleton","GO:0003723//RNA binding;GO:0005524//ATP binding;GO:0051731//polynucleotide 5'-hydroxyl-kinase activity","GO:0000448//cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000460//maturation of 5.8S rRNA;GO:0006364//rRNA processing","K06947//polynucleotide 5'-hydroxyl-kinase GRC3/NOL9 [EC:2.7.1.-]","NP_078930.3//polynucleotide 5'-hydroxyl-kinase NOL9 [Homo sapiens]",4]
[9276,3142,29.3,25.09,-0.223788193900438,1.40311222802437E-3,"*",4.037E-4,"COPB2","GO:0030126//COPI vesicle coat;GO:0000139//Golgi membrane","GO:0005198//structural molecule activity","GO:0006886//intracellular protein transport;GO:1901998//toxin transport;GO:0006891//intra-Golgi vesicle-mediated transport","K17302//coatomer subunit beta'","EHH16722.1//hypothetical protein EGK_12054 [Macaca mulatta]","2//1"]
[54811,5607,3.91,3.35,-0.223007511962218,0.136459980969163,"*",0.0678712,"ZNF562","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","EHB03705.1//Zinc finger protein 26 [Heterocephalus glaber];XP_015296267.1//PREDICTED: zinc finger protein 266 [Macaca fascicularis]","1//3;3//A2MP1"]
[130951,2555,0.28,0.24,-0.222392421336448,0.873899676907426,"*",0.806664,"M1AP","GO:0016021//integral component of membrane;GO:0005737//cytoplasm","GO:0042802//identical protein binding","GO:0006396//RNA processing;GO:0007127//meiosis I;GO:0030154//cell differentiation;GO:0051308//male meiosis chromosome separation;GO:0031497//chromatin assembly;GO:0007283//spermatogenesis;GO:0007292//female gamete generation","K17985//activating molecule in BECN1-regulated autophagy protein 1","XP_009440876.2//PREDICTED: meiosis 1 arrest protein isoform X2 [Pan troglodytes];XP_016799370.1//PREDICTED: meiosis 1 arrest protein isoform X1 [Pan troglodytes];XP_006712009.1//PREDICTED: meiosis 1 arrest protein isoform X1 [Homo sapiens]","4;1//3"]
[139105,4017,0.84,0.72,-0.222392421336448,1.02216308556701,"*",0.993112,"BEND2","NA","NA","NA","K22069//LYR motif-containing protein 4;K12581//CCR4-NOT transcription complex subunit 7/8;K11447//histone demethylase [EC:1.14.11.-];K08857//NIMA (never in mitosis gene a)-related kinase 1/4/5 [EC:2.7.11.1];K01064//wingless-type MMTV integration site family, member 9;K04460//serine/threonine-protein phosphatase 5 [EC:3.1.3.16]","NP_001171696.1//BEN domain-containing protein 2 isoform 2 [Homo sapiens];NP_699177.2//BEN domain-containing protein 2 isoform 1 [Homo sapiens]","1//3;4"]
[3683,4974,0.35,0.3,-0.222392421336448,0.749413224336251,"*",0.6485,"ITGAL","GO:0016020//membrane;GO:0008305//integrin complex;GO:0070062//extracellular exosome;GO:0034687//integrin alphaL-beta2 complex;GO:0009986//cell surface;GO:0035579//specific granule membrane;GO:0005886//plasma membrane","GO:0046872//metal ion binding;GO:0050839//cell adhesion molecule binding;GO:0046982//protein heterodimerization activity;GO:0032403//protein complex binding;GO:0030369//ICAM-3 receptor activity","GO:0043113//receptor clustering;GO:0007165//signal transduction;GO:0007159//leukocyte cell-cell adhesion;GO:0050900//leukocyte migration;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0006954//inflammatory response;GO:0002291//T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell;GO:0007160//cell-matrix adhesion;GO:0006928//movement of cell or subcellular component;GO:0007155//cell adhesion;GO:0030198//extracellular matrix organization;GO:0043312//neutrophil degranulation;GO:0007229//integrin-mediated signaling pathway;GO:0050776//regulation of immune response;GO:0006909//phagocytosis","K05718//integrin alpha L","NP_002200.2//integrin alpha-L isoform a precursor [Homo sapiens]","1//3;2//1"]
[4862,4004,54.95,47.14,-0.221167722586426,{"v":3.83958392112676e-07,"d":"3.84E-07"},"*",{"v":5.97306e-08,"d":"5.97E-08"},"NPAS2","NA","NA","NA","K09026//neuronal PAS domain-containing protein 2","XP_008006376.1//PREDICTED: neuronal PAS domain-containing protein 2 isoform X1 [Chlorocebus sabaeus]","3//A2MP1"]
[55646,1584,14.93,12.81,-0.220943689792895,0.0527666813141684,"*",0.0225218,"LYAR","GO:0005634//nucleus;GO:0005730//nucleolus","GO:0003723//RNA binding;GO:0046872//metal ion binding","NA","K15263//cell growth-regulating nucleolar protein","NP_060286.1//cell growth-regulating nucleolar protein [Homo sapiens]","1//3;2//1"]
[81609,6405,9.53,8.18,-0.220375370968193,0.00775547208333333,"*",0.00261008,"SNX27","GO:0005768//endosome;GO:0030904//retromer complex;GO:0005654//nucleoplasm;GO:0031901//early endosome membrane;GO:0005829//cytosol;GO:0005622//intracellular;GO:0071203//WASH complex;GO:0001772//immunological synapse;GO:0005769//early endosome","GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0035091//phosphatidylinositol binding","GO:0006886//intracellular protein transport;GO:0016197//endosomal transport;GO:0007165//signal transduction;GO:1990126//retrograde transport, endosome to plasma membrane;GO:0001770//establishment of natural killer cell polarity;GO:0008333//endosome to lysosome transport","K17936//sorting nexin-27","NP_001317652.1//sorting nexin-27 isoform 1 [Homo sapiens];NP_112180.4//sorting nexin-27 isoform 2 [Homo sapiens]","1//3;5"]
[819,2255,11.4,9.79,-0.219653059448409,0.128422144506898,"*",0.0629328,"CAMLG","GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane","GO:0050839//cell adhesion molecule binding","GO:0001881//receptor recycling;GO:0007165//signal transduction;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0006952//defense response;GO:0016032//viral process","K09228//KRAB domain-containing zinc finger protein;K01368//cathepsin S [EC:3.4.22.27];K01064//wingless-type MMTV integration site family, member 9;K09488//TNF receptor-associated protein 1","XP_007107121.1//PREDICTED: calcium signal-modulating cyclophilin ligand isoform X1 [Physeter catodon]","3//A2MP1"]
[90226,1546,5.6,4.81,-0.219389933174924,0.441828053613272,"*",0.295096,"UCN2","NA","NA","NA","K05257//urocortin 2/3","XP_007982322.1//PREDICTED: urocortin-2 [Chlorocebus sabaeus]","3//A2MP1"]
[64769,4784,7.83,6.73,-0.218405802680723,0.0642663188322839,"*",0.028114,"MEAF6","GO:0035267//NuA4 histone acetyltransferase complex;GO:0005654//nucleoplasm;GO:0070776//MOZ/MORF histone acetyltransferase complex;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0016604//nuclear body;GO:0000777//condensed chromosome kinetochore;GO:0000776//kinetochore;GO:0000123//histone acetyltransferase complex","NA","GO:0006355//regulation of transcription, DNA-templated;GO:0043981//histone H4-K5 acetylation;GO:0043968//histone H2A acetylation;GO:0016573//histone acetylation;GO:0006351//transcription, DNA-templated;GO:0044154//histone H3-K14 acetylation;GO:1901796//regulation of signal transduction by p53 class mediator;GO:0043982//histone H4-K8 acetylation;GO:0043983//histone H4-K12 acetylation","K11344//chromatin modification-related protein EAF6","NP_001230385.1//chromatin modification-related protein MEAF6 [Sus scrofa];NP_073593.2//chromatin modification-related protein MEAF6 isoform 1 [Homo sapiens];XP_005204892.1//PREDICTED: chromatin modification-related protein MEAF6 isoform X2 [Bos taurus]","1//3;5"]
[81887,2434,36.13,31.06,-0.218139425045142,0.0025417163848854,"*",0.000770598,"LAS1L","GO:0016020//membrane;GO:0005654//nucleoplasm;GO:0071339//MLL1 complex;GO:0005730//nucleolus;GO:0030687//preribosome, large subunit precursor;GO:0005737//cytoplasm","GO:0003723//RNA binding","GO:0000470//maturation of LSU-rRNA;GO:0000460//maturation of 5.8S rRNA;GO:0006325//chromatin organization;GO:0006364//rRNA processing;GO:0000478//endonucleolytic cleavage involved in rRNA processing","K16912//ribosomal biogenesis protein LAS1","NP_001164120.1//ribosomal biogenesis protein LAS1L isoform 2 [Homo sapiens];XP_011529347.1//PREDICTED: ribosomal biogenesis protein LAS1L isoform X3 [Homo sapiens];NP_112483.1//ribosomal biogenesis protein LAS1L isoform 1 [Homo sapiens]","4;1//3"]
[286205,12187,2.57,2.21,-0.217721989802446,0.0984286536572272,"*",0.0459116,"SCAI","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0016021//integral component of membrane;GO:0005737//cytoplasm","GO:0003714//transcription corepressor activity","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0030336//negative regulation of cell migration;GO:0035024//negative regulation of Rho protein signal transduction","K11447//histone demethylase [EC:1.14.11.-]","NP_775961.2//protein SCAI isoform 1 [Homo sapiens];XP_017911250.1//PREDICTED: protein SCAI isoform X1 [Capra hircus]","4;2//1"]
[9991,6564,26.28,22.61,-0.217004283570801,{"v":4.18702699322799e-18,"d":"4.19E-18"},"*",{"v":2.32234e-19,"d":"2.32E-19"},"PTBP3","GO:0005634//nucleus","GO:0003723//RNA binding","GO:0006397//mRNA processing;GO:0033119//negative regulation of RNA splicing;GO:0009653//anatomical structure morphogenesis;GO:0043249//erythrocyte maturation;GO:0008380//RNA splicing;GO:0045595//regulation of cell differentiation","K17844//polypyrimidine tract-binding protein 3","XP_019309725.1//PREDICTED: polypyrimidine tract-binding protein 3 isoform X2 [Panthera pardus];NP_001231827.1//polypyrimidine tract-binding protein 3 isoform 6 [Homo sapiens];NP_001231825.1//polypyrimidine tract-binding protein 3 isoform 4 [Homo sapiens];AAH39896.1//Similar to ROD1 regulator of differentiation 1 (S. pombe), partial [Homo sapiens];XP_019309724.1//PREDICTED: polypyrimidine tract-binding protein 3 isoform X1 [Panthera pardus]","6;1//3;2//1"]
[57107,3568,5.39,4.64,-0.216160467624933,0.210880127816412,"*",0.1139022,"PDSS2","GO:0005759//mitochondrial matrix;GO:1990234//transferase complex;GO:0005829//cytosol;GO:0005739//mitochondrion","GO:0046982//protein heterodimerization activity;GO:0050347//trans-octaprenyltranstransferase activity;GO:0000010//trans-hexaprenyltranstransferase activity","GO:0008299//isoprenoid biosynthetic process;GO:0050878//regulation of body fluid levels;GO:0006744//ubiquinone biosynthetic process;GO:0051290//protein heterotetramerization","K12505//decaprenyl-diphosphate synthase subunit 2 [EC:2.5.1.91]","NP_065114.3//decaprenyl-diphosphate synthase subunit 2 [Homo sapiens]","3//A2MP1"]
[388759,2258,2.16,1.86,-0.215728691055437,0.560829824798544,"*",0.405192,"C1orf229","NA","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K16506//protocadherin Fat 1/2/3;K07560//D-tyrosyl-tRNA(Tyr) deacylase [EC:3.1.-.-];K04487//cysteine desulfurase [EC:2.8.1.7]","NP_997284.1//putative uncharacterized protein C1orf229 [Homo sapiens]","2//1"]
[10795,5700,1.37,1.18,-0.215389033598686,0.386045775958466,"*",0.242058,"ZNF268","GO:0005634//nucleus;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0007346//regulation of mitotic cell cycle;GO:0046022//positive regulation of transcription from RNA polymerase II promoter during mitotic cell cycle;GO:0030335//positive regulation of cell migration;GO:0006355//regulation of transcription, DNA-templated;GO:0008588//release of cytoplasmic sequestered NF-kappaB;GO:0071356//cellular response to tumor necrosis factor;GO:0043497//regulation of protein heterodimerization activity;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0043065//positive regulation of apoptotic process;GO:0090073//positive regulation of protein homodimerization activity;GO:0001934//positive regulation of protein phosphorylation;GO:0071157//negative regulation of cell cycle arrest;GO:0045597//positive regulation of cell differentiation;GO:0008285//negative regulation of cell proliferation;GO:0030154//cell differentiation;GO:0006351//transcription, DNA-templated;GO:0043066//negative regulation of apoptotic process;GO:0045732//positive regulation of protein catabolic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0008284//positive regulation of cell proliferation","K09228//KRAB domain-containing zinc finger protein","NP_003406.1//zinc finger protein 268 isoform a [Homo sapiens]","1//3;2//1"]
[6386,2170,74.63,64.29,-0.215161335387994,{"v":3.02397233165532e-05,"d":"3.02E-05"},"*",{"v":6.39286E-6,"d":"6.39E-06"},"SDCBP","GO:0016020//membrane;GO:0005615//extracellular space;GO:0042470//melanosome;GO:0005737//cytoplasm;GO:0005895//interleukin-5 receptor complex;GO:0035578//azurophil granule lumen;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005856//cytoskeleton;GO:0070062//extracellular exosome;GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0072562//blood microparticle;GO:0005925//focal adhesion;GO:0005622//intracellular;GO:0005912//adherens junction;GO:1903561//extracellular vesicle;GO:0045121//membrane raft;GO:0005789//endoplasmic reticulum membrane","GO:0050839//cell adhesion molecule binding;GO:0005137//interleukin-5 receptor binding;GO:0042043//neurexin family protein binding;GO:0045545//syndecan binding;GO:0047485//protein N-terminus binding;GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity;GO:0019838//growth factor binding;GO:0042803//protein homodimerization activity;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0008093//cytoskeletal adaptor activity;GO:0005109//frizzled binding;GO:0045296//cadherin binding;GO:0008022//protein C-terminus binding;GO:0046875//ephrin receptor binding","GO:0046330//positive regulation of JNK cascade;GO:1903543//positive regulation of exosomal secretion;GO:0007346//regulation of mitotic cell cycle;GO:0030335//positive regulation of cell migration;GO:0030307//positive regulation of cell growth;GO:0035556//intracellular signal transduction;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0043312//neutrophil degranulation;GO:0006612//protein targeting to membrane;GO:0030036//actin cytoskeleton organization;GO:0048013//ephrin receptor signaling pathway;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0042327//positive regulation of phosphorylation;GO:0007268//chemical synaptic transmission;GO:0007265//Ras protein signal transduction;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0002091//negative regulation of receptor internalization;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0006930//substrate-dependent cell migration, cell extension;GO:0008284//positive regulation of cell proliferation;GO:1903553//positive regulation of extracellular exosome assembly","K17254//syntenin-1","NP_001335269.1//syntenin-1 isoform 6 [Homo sapiens];NP_001335270.1//syntenin-1 isoform 7 [Homo sapiens];NP_001335268.1//syntenin-1 isoform 5 [Homo sapiens];NP_001317466.1//syntenin-1 isoform 4 [Homo sapiens]","1//3;3//A2MP1"]
[10794,3602,0.29,0.25,-0.214124805352847,0.794388124453224,"*",0.704874,"ZNF460","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_012414047.1//PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 91-like [Trichechus manatus latirostris]","1//3;3//A2MP1"]
[404636,2473,23.37,20.15,-0.213877895367496,0.0206263976333721,"*",0.00776944,"FAM45A","NA","NA","NA","NA","NP_996892.1//protein FAM45A isoform 1 [Homo sapiens];NP_001290040.1//protein FAM45A isoform 2 [Homo sapiens];NP_001290041.1//protein FAM45A isoform 3 [Homo sapiens];XP_012594603.1//protein FAM45A isoform X4 [Microcebus murinus]","1//3;3//A2MP1"]
[401207,5680,1.82,1.57,-0.213173891307069,0.486791002827693,"*",0.334086,"C5orf63","NA","NA","GO:0055114//oxidation-reduction process","K00626//acetyl-CoA C-acetyltransferase [EC:2.3.1.9]","XP_011945500.1//PREDICTED: glutaredoxin-like protein C5orf63 homolog isoform X1 [Cercocebus atys];XP_008950280.1//PREDICTED: glutaredoxin-like protein C5orf63 homolog isoform X1 [Pan paniscus]","1//3"]
[119385,3155,0.73,0.63,-0.212544635380101,0.624836251014674,"*",0.501152,"AGAP11","NA","NA","NA","K12491//Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1/3","XP_009234323.1//PREDICTED: LOW QUALITY PROTEIN: arf-GAP with GTPase, ANK repeat and PH domain-containing protein 11-like [Pongo abelii]","1//3"]
[9213,8096,9.54,8.24,-0.211344928822293,0.000799479397172823,"*",2.19514E-4,"XPR1","GO:0031226//intrinsic component of plasma membrane;GO:0016021//integral component of membrane;GO:0005737//cytoplasm","GO:0015114//phosphate ion transmembrane transporter activity;GO:0015562//efflux transmembrane transporter activity;GO:0004872//receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0000822//inositol hexakisphosphate binding;GO:0001618//virus receptor activity;GO:0004930//G-protein coupled receptor activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0030643//cellular phosphate ion homeostasis;GO:0035435//phosphate ion transmembrane transport;GO:0009615//response to virus","K10352//myosin heavy chain;K06245//laminin, beta 4;K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K02927//large subunit ribosomal protein L40e;K01064//wingless-type MMTV integration site family, member 9;K12025//tripartite motif-containing protein 52","NP_001129141.1//xenotropic and polytropic retrovirus receptor 1 isoform 2 [Homo sapiens];XP_009238733.1//PREDICTED: xenotropic and polytropic retrovirus receptor 1 [Pongo abelii]","1//3;3//A2MP1"]
[152002,2505,11.34,9.8,-0.210566985939658,0.182716958931553,"*",0.0959224,"XXYLT1","GO:0030176//integral component of endoplasmic reticulum membrane","GO:0035252//UDP-xylosyltransferase activity;GO:0000287//magnesium ion binding;GO:0016757//transferase activity, transferring glycosyl groups;GO:0030145//manganese ion binding","GO:0016266//O-glycan processing","K17455//fascin 1/2;K12489//Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein;K21125//mucin-5AC;K09291//nucleoprotein TPR;K09668//glycosyltransferase-like protein LARGE [EC:2.4.2.- 2.4.1.-]","NP_689744.3//xyloside xylosyltransferase 1 isoform 1 [Homo sapiens];NP_001294998.1//xyloside xylosyltransferase 1 isoform 2 [Homo sapiens]","4;1//3"]
[6509,4189,7.01,6.06,-0.210096650537672,0.092203122156013,"*",0.042621,"SLC1A4","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0030425//dendrite;GO:0042470//melanosome;GO:0005882//intermediate filament;GO:0043025//neuronal cell body;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0015193//L-proline transmembrane transporter activity;GO:0034590//L-hydroxyproline transmembrane transporter activity;GO:0015293//symporter activity;GO:0015186//L-glutamine transmembrane transporter activity;GO:0015195//L-threonine transmembrane transporter activity;GO:0005254//chloride channel activity;GO:0015180//L-alanine transmembrane transporter activity;GO:0015194//L-serine transmembrane transporter activity;GO:0015184//L-cystine transmembrane transporter activity;GO:0015171//amino acid transmembrane transporter activity","GO:0015826//threonine transport;GO:0006868//glutamine transport;GO:0015808//L-alanine transport;GO:0015824//proline transport;GO:0050890//cognition;GO:0015825//L-serine transport;GO:0006865//amino acid transport;GO:0035249//synaptic transmission, glutamatergic;GO:0034589//hydroxyproline transport;GO:0015811//L-cystine transport","K05615//solute carrier family 1 (glutamate/neutral amino acid transporter), member 4","AAA19438.1//neutral amino acid transporter [Homo sapiens];NP_003029.2//neutral amino acid transporter A isoform 1 [Homo sapiens];XP_004369325.1//PREDICTED: neutral amino acid transporter A isoform X2 [Trichechus manatus latirostris]","1//3;4"]
[54557,5453,4.44,3.84,-0.20945336562895,0.161089729010239,"*",0.0827332,"SGTB","NA","NA","NA","K16365//small glutamine-rich tetratricopeptide repeat-containing protein alpha","NP_061945.1//small glutamine-rich tetratricopeptide repeat-containing protein beta [Homo sapiens]","2//1"]
[23093,4773,8.24,7.13,-0.20874226073933,0.0680332523741825,"*",0.0299578,"TTLL5","GO:0005929//cilium;GO:0005634//nucleus;GO:0005874//microtubule;GO:0005829//cytosol;GO:0005813//centrosome;GO:0005886//plasma membrane","GO:0070740//tubulin-glutamic acid ligase activity;GO:0005524//ATP binding","GO:0060041//retina development in camera-type eye;GO:0018095//protein polyglutamylation;GO:0009566//fertilization;GO:0007288//sperm axoneme assembly;GO:0006351//transcription, DNA-templated","K16602//tubulin polyglutamylase TTLL5 [EC:6.-.-.-]","NP_055887.3//tubulin polyglutamylase TTLL5 [Homo sapiens]",4]
[6310,10596,1.04,0.9,-0.208586621811417,0.392314571513885,"*",0.24675,"ATXN1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0016363//nuclear matrix;GO:0042405//nuclear inclusion body;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0008022//protein C-terminus binding;GO:0008266//poly(U) RNA binding;GO:0042802//identical protein binding;GO:0034046//poly(G) binding;GO:0043621//protein self-association","GO:0006396//RNA processing;GO:0045892//negative regulation of transcription, DNA-templated;GO:0051168//nuclear export;GO:0006351//transcription, DNA-templated","K11432//histone-lysine N-methyltransferase PRDM2 [EC:2.1.1.43];K21125//mucin-5AC","NP_000323.2//ataxin-1 [Homo sapiens]","1//3;3//A2MP1"]
[5414,1814,0.67,0.58,-0.208108195330201,0.91107235664709,"*",0.854608,"2019-09-04","GO:0097227//sperm annulus;GO:0031105//septin complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0043209//myelin sheath;GO:0005739//mitochondrion","GO:0000287//magnesium ion binding;GO:0005198//structural molecule activity;GO:0005525//GTP binding;GO:0042803//protein homodimerization activity;GO:0003924//GTPase activity","GO:0030382//sperm mitochondrion organization;GO:0031398//positive regulation of protein ubiquitination;GO:0051260//protein homooligomerization;GO:0007420//brain development;GO:0006915//apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway;GO:0051301//cell division;GO:0048240//sperm capacitation;GO:0007049//cell cycle;GO:0042981//regulation of apoptotic process","K16943//septin 4","NP_001185642.1//septin-4 isoform 4 [Homo sapiens];NP_536340.1//septin-4 isoform 2 [Homo sapiens];NP_001243711.1//septin-4 isoform 5 [Homo sapiens];NP_004565.1//septin-4 isoform 1 [Homo sapiens];XP_006722012.1//PREDICTED: septin-4 isoform X1 [Homo sapiens];XP_011731354.1//PREDICTED: uncharacterized protein LOC105476826 isoform X1 [Macaca nemestrina]","4;1//3;3//A2MP1"]
[55171,2725,9.62,8.33,-0.207720398404494,0.145084684392488,"*",0.0730328,"TBCCD1","GO:0031616//spindle pole centrosome;GO:0005737//cytoplasm","NA","GO:0051661//maintenance of centrosome location;GO:0030334//regulation of cell migration;GO:0051684//maintenance of Golgi location;GO:0008360//regulation of cell shape","K16810//TBCC domain-containing protein 1","NP_001273678.1//TBCC domain-containing protein 1 isoform b [Homo sapiens];NP_060608.1//TBCC domain-containing protein 1 isoform a [Homo sapiens]","4;1//3"]
[93487,6469,25.41,22.01,-0.207237230161797,{"v":4.93155135067162e-05,"d":"4.93E-05"},"*",{"v":1.080224e-05,"d":"1.08E-05"},"MAPK1IP1L","NA","GO:0016301//kinase activity","NA","K10955//mucin-2;K06831//galectin-3","XP_011535664.2//PREDICTED: MAPK-interacting and spindle-stabilizing protein-like isoform X1 [Homo sapiens]","3//A2MP1"]
[3987,4398,18.14,15.72,-0.206573238269916,0.00611925675285171,"*",2.01498E-3,"LIMS1","GO:0005925//focal adhesion;GO:0043234//protein complex;GO:0005829//cytosol;GO:0005911//cell-cell junction;GO:0005886//plasma membrane;GO:0048471//perinuclear region of cytoplasm","GO:0046872//metal ion binding;GO:0008270//zinc ion binding;GO:0019901//protein kinase binding","GO:0051291//protein heterooligomerization;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045184//establishment of protein localization;GO:0034329//cell junction assembly;GO:0051894//positive regulation of focal adhesion assembly;GO:0007569//cell aging;GO:0043547//positive regulation of GTPase activity;GO:0010628//positive regulation of gene expression;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:0045216//cell-cell junction organization;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0010811//positive regulation of cell-substrate adhesion","K05760//paxillin","XP_005340991.1//LIM and senescent cell antigen-like-containing domain protein 1 isoform X4 [Ictidomys tridecemlineatus];NP_001180412.1//LIM and senescent cell antigen-like-containing domain protein 1 isoform d [Homo sapiens];XP_012593079.1//LIM and senescent cell antigen-like-containing domain protein 1 isoform X4 [Microcebus murinus];NP_001180414.1//LIM and senescent cell antigen-like-containing domain protein 1 isoform a [Homo sapiens];NP_001180411.1//LIM and senescent cell antigen-like-containing domain protein 1 isoform c [Homo sapiens]","1//3;2//1;5"]
[375323,4895,0.15,0.13,-0.206450877467426,0.882274897744158,"*",0.817764,"LHFPL4","GO:0016021//integral component of membrane","NA","NA","K03006//DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6];K18631//tektin-4","XP_019839659.1//PREDICTED: lipoma HMGIC fusion partner-like 4 protein [Bos indicus]","2//1"]
[91893,3081,1.73,1.5,-0.205809537140844,0.63751046814864,"*",0.481146,"FDXACB1","GO:0009328//phenylalanine-tRNA ligase complex","GO:0004826//phenylalanine-tRNA ligase activity","GO:0006432//phenylalanyl-tRNA aminoacylation","K03846//alpha-1,2-mannosyltransferase [EC:2.4.1.259 2.4.1.261]","NP_612387.1//ferredoxin-fold anticodon-binding domain-containing protein 1 [Homo sapiens]","2//1"]
[54733,3184,14.51,12.59,-0.204769236347728,0.0534272748681898,"*",0.0228372,"SLC35F2","GO:0016021//integral component of membrane","NA","GO:0006810//transport","K15287//solute carrier family 35, member F1/2","NP_059985.2//solute carrier family 35 member F2 [Homo sapiens]",4]
[3609,4984,77.24,67.02,-0.204756477746179,{"v":4.25758854640981e-10,"d":"4.26E-10"},"*",{"v":4.5657e-11,"d":"4.57E-11"},"ILF3","GO:0016020//membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0030529//intracellular ribonucleoprotein complex;GO:0005576//extracellular region;GO:0005739//mitochondrion","GO:0003723//RNA binding;GO:0003677//DNA binding;GO:0003725//double-stranded RNA binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0017148//negative regulation of translation;GO:0045071//negative regulation of viral genome replication;GO:0006468//protein phosphorylation;GO:0051607//defense response to virus;GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated","K13090//interleukin enhancer-binding factor 3","NP_060090.2//interleukin enhancer-binding factor 3 isoform d [Homo sapiens];NP_036350.2//interleukin enhancer-binding factor 3 isoform a [Homo sapiens];NP_001131145.1//interleukin enhancer-binding factor 3 isoform e [Homo sapiens];XP_011728190.1//PREDICTED: interleukin enhancer-binding factor 3 isoform X3 [Macaca nemestrina];NP_004507.2//interleukin enhancer-binding factor 3 isoform b [Homo sapiens]","1//3;3//A2MP1;2//1"]
[10291,5159,32.8,28.47,-0.20425332176318,{"v":4.94114466038275e-05,"d":"4.94E-05"},"*",{"v":1.082944e-05,"d":"1.08E-05"},"SF3A1","GO:0005684//U2-type spliceosomal complex;GO:0071004//U2-type prespliceosome;GO:0005654//nucleoplasm;GO:0005686//U2 snRNP;GO:0005681//spliceosomal complex;GO:0016607//nuclear speck;GO:0071013//catalytic step 2 spliceosome","GO:0003723//RNA binding","GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0000398//mRNA splicing, via spliceosome;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0000389//mRNA 3'-splice site recognition","K12825//splicing factor 3A subunit 1","NP_005868.1//splicing factor 3A subunit 1 [Homo sapiens]",5]
[26015,4709,6.69,5.81,-0.203468047236932,0.124275614627213,"*",0.0602084,"RPAP1","GO:0005634//nucleus","GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0003677//DNA binding","GO:0006366//transcription from RNA polymerase II promoter","K20826//RNA polymerase II-associated protein 1","NP_056355.2//RNA polymerase II-associated protein 1 [Homo sapiens]","3//A2MP1"]
[1718,4286,31.94,27.74,-0.20339652508763,0.000320628328557312,"*",{"v":8.1251e-05,"d":"8.13E-05"},"DHCR24","GO:0016020//membrane;GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0000139//Golgi membrane;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0016614//oxidoreductase activity, acting on CH-OH group of donors;GO:0050614//delta24-sterol reductase activity;GO:0000246//delta24(24-1) sterol reductase activity;GO:0042605//peptide antigen binding;GO:0016628//oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;GO:0050660//flavin adenine dinucleotide binding;GO:0019899//enzyme binding","GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0042987//amyloid precursor protein catabolic process;GO:0043588//skin development;GO:0009888//tissue development;GO:0055114//oxidation-reduction process;GO:0007050//cell cycle arrest;GO:0008202//steroid metabolic process;GO:0030539//male genitalia development;GO:0008285//negative regulation of cell proliferation;GO:0033489//cholesterol biosynthetic process via desmosterol;GO:0006695//cholesterol biosynthetic process;GO:0043066//negative regulation of apoptotic process;GO:0006915//apoptotic process;GO:0061024//membrane organization;GO:0031639//plasminogen activation;GO:0006979//response to oxidative stress;GO:0033490//cholesterol biosynthetic process via lathosterol;GO:0009725//response to hormone;GO:0008104//protein localization;GO:0007265//Ras protein signal transduction;GO:1901214//regulation of neuron death","K09828//Delta24-sterol reductase [EC:1.3.1.72 1.3.1.-]","XP_007976807.1//PREDICTED: delta(24)-sterol reductase [Chlorocebus sabaeus]","3//A2MP1"]
[8915,3114,6.66,5.79,-0.201958829082026,0.230645475858971,"*",0.128592,"BCL10","GO:0042101//T cell receptor complex;GO:0005634//nucleus;GO:0005881//cytoplasmic microtubule;GO:0005764//lysosome;GO:0046696//lipopolysaccharide receptor complex;GO:0001772//immunological synapse;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0045121//membrane raft;GO:0043234//protein complex;GO:0005829//cytosol;GO:0032449//CBM complex;GO:0005886//plasma membrane","GO:0043422//protein kinase B binding;GO:0002020//protease binding;GO:0019209//kinase activator activity;GO:0042802//identical protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0043621//protein self-association;GO:0019901//protein kinase binding;GO:0051059//NF-kappaB binding;GO:0008022//protein C-terminus binding;GO:0003713//transcription coactivator activity;GO:0019900//kinase binding;GO:0008134//transcription factor binding;GO:0019899//enzyme binding","GO:0016064//immunoglobulin mediated immune response;GO:0071260//cellular response to mechanical stimulus;GO:0051260//protein homooligomerization;GO:0042109//lymphotoxin A biosynthetic process;GO:0043065//positive regulation of apoptotic process;GO:0070231//T cell apoptotic process;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:0002906//negative regulation of mature B cell apoptotic process;GO:0045087//innate immune response;GO:0051259//protein oligomerization;GO:0001783//B cell apoptotic process;GO:0006915//apoptotic process;GO:0002250//adaptive immune response;GO:0042226//interleukin-6 biosynthetic process;GO:0042327//positive regulation of phosphorylation;GO:0001843//neural tube closure;GO:0009620//response to fungus;GO:0016567//protein ubiquitination;GO:0032094//response to food;GO:0002237//response to molecule of bacterial origin;GO:0045893//positive regulation of transcription, DNA-templated;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0051291//protein heterooligomerization;GO:0050852//T cell receptor signaling pathway;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0031398//positive regulation of protein ubiquitination;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0008219//cell death;GO:0002224//toll-like receptor signaling pathway;GO:0006968//cellular defense response;GO:0050870//positive regulation of T cell activation;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0050856//regulation of T cell receptor signaling pathway;GO:0032765//positive regulation of mast cell cytokine production;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0042981//regulation of apoptotic process;GO:0045416//positive regulation of interleukin-8 biosynthetic process","K07368//B-cell CLL/lymphoma 10","XP_003892185.1//B-cell lymphoma/leukemia 10 [Papio anubis]","4;1//3"]
[9832,8995,0.23,0.2,-0.201633861169651,0.690087883852478,"*",0.572798,"JAKMIP2","GO:0005794//Golgi apparatus","GO:0016301//kinase activity;GO:0019900//kinase binding;GO:0008017//microtubule binding","NA","K20478//golgin subfamily B member 1","NP_001257863.1//janus kinase and microtubule-interacting protein 2 isoform 2 [Homo sapiens];NP_001269211.1//janus kinase and microtubule-interacting protein 2 isoform 4 [Homo sapiens];XP_012880965.1//PREDICTED: janus kinase and microtubule-interacting protein 2 isoform X1 [Dipodomys ordii];NP_001257870.1//janus kinase and microtubule-interacting protein 2 isoform 1 [Homo sapiens]","1//3;4"]
[145748,2670,2.76,2.4,-0.20163386116965,0.355801209836066,"*",0.217392,"LYSMD4","GO:0016021//integral component of membrane","NA","NA","NA","NP_001271348.1//lysM and putative peptidoglycan-binding domain-containing protein 4 isoform c [Homo sapiens];NP_689662.2//lysM and putative peptidoglycan-binding domain-containing protein 4 isoform a [Homo sapiens];NP_001271347.1//lysM and putative peptidoglycan-binding domain-containing protein 4 isoform b [Homo sapiens];NP_001271349.1//lysM and putative peptidoglycan-binding domain-containing protein 4 isoform d [Homo sapiens];XP_016877416.1//PREDICTED: lysM and putative peptidoglycan-binding domain-containing protein 4 isoform X5 [Homo sapiens]","1//3;3//A2MP1"]
[2774,5661,8.18,7.12,-0.200223601975351,0.0388045998534127,"*",0.01590906,"GNAL","GO:0070062//extracellular exosome;GO:0005834//heterotrimeric G-protein complex;GO:0005886//plasma membrane","GO:0031683//G-protein beta/gamma-subunit complex binding;GO:0046872//metal ion binding;GO:0001664//G-protein coupled receptor binding;GO:0004871//signal transducer activity;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0007165//signal transduction;GO:0007190//activation of adenylate cyclase activity;GO:0001975//response to amphetamine;GO:0031000//response to caffeine;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0007191//adenylate cyclase-activating dopamine receptor signaling pathway","K04633//guanine nucleotide-binding protein G(olf) subunit alpha","NP_001135811.1//guanine nucleotide-binding protein G(olf) subunit alpha isoform 2 [Homo sapiens];XP_013369712.1//PREDICTED: guanine nucleotide-binding protein G(olf) subunit alpha isoform X1 [Chinchilla lanigera];NP_892023.1//guanine nucleotide-binding protein G(olf) subunit alpha isoform 1 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[54952,1884,5.34,4.65,-0.19960902569216,0.45165573581742,"*",0.303526,"TRNAU1AP","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0003723//RNA binding","GO:0001514//selenocysteine incorporation","K13201//nucleolysin TIA-1/TIAR;K13126//polyadenylate-binding protein;K15174//RNA polymerase II-associated factor 1","XP_017390246.1//PREDICTED: tRNA selenocysteine 1-associated protein 1 isoform X1 [Cebus capucinus imitator]",4]
[93621,2127,67.13,58.46,-0.199507813269682,0.000166925182513661,"*",{"v":4.01586e-05,"d":"4.02E-05"},"MRFAP1","GO:0005634//nucleus;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm","NA","NA","K07190//phosphorylase kinase alpha/beta subunit;K01064//wingless-type MMTV integration site family, member 9","XP_011770269.1//PREDICTED: MORF4 family-associated protein 1-like [Macaca nemestrina]","1//3;2//1"]
[1143,2267,0.7,0.61,-0.19854567938208,0.563911062851215,"*",0.408336,"CHRNB4","GO:0005892//acetylcholine-gated channel complex;GO:0030054//cell junction;GO:0043005//neuron projection;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane;GO:0070821//tertiary granule membrane;GO:0005886//plasma membrane;GO:0045211//postsynaptic membrane","GO:0015276//ligand-gated ion channel activity;GO:0042166//acetylcholine binding;GO:0008144//drug binding;GO:0046982//protein heterodimerization activity;GO:0022848//acetylcholine-gated cation-selective channel activity;GO:0015464//acetylcholine receptor activity","GO:0051291//protein heterooligomerization;GO:0035094//response to nicotine;GO:0051971//positive regulation of transmission of nerve impulse;GO:0035095//behavioral response to nicotine;GO:0007165//signal transduction;GO:0006939//smooth muscle contraction;GO:0006811//ion transport;GO:0006940//regulation of smooth muscle contraction;GO:0007271//synaptic transmission, cholinergic;GO:0007626//locomotory behavior;GO:0001508//action potential;GO:0043312//neutrophil degranulation;GO:0046928//regulation of neurotransmitter secretion;GO:0060084//synaptic transmission involved in micturition","K04815//nicotinic acetylcholine receptor beta-4","NP_000741.1//neuronal acetylcholine receptor subunit beta-4 isoform 1 precursor [Homo sapiens];NP_001243496.1//neuronal acetylcholine receptor subunit beta-4 isoform 2 precursor [Homo sapiens]","4;2//1"]
[80221,2135,7.16,6.24,-0.198413558402008,0.292708632245599,"*",0.170707,"ACSF2","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0005524//ATP binding;GO:0003824//catalytic activity;GO:0016874//ligase activity;GO:0003996//acyl-CoA ligase activity","GO:0008152//metabolic process;GO:0006631//fatty acid metabolic process;GO:0006637//acyl-CoA metabolic process","K00666//fatty-acyl-CoA synthase [EC:6.2.1.-]","NP_001275899.1//acyl-CoA synthetase family member 2, mitochondrial isoform 4 [Homo sapiens];AAH14123.1//Acyl-CoA synthetase family member 2 [Homo sapiens];NP_001275898.1//acyl-CoA synthetase family member 2, mitochondrial isoform 3 [Homo sapiens];NP_079425.3//acyl-CoA synthetase family member 2, mitochondrial isoform 2 precursor [Homo sapiens];NP_001275897.1//acyl-CoA synthetase family member 2, mitochondrial isoform 1 [Homo sapiens]","1//3;5"]
[5475,2687,0.39,0.34,-0.197939377611909,0.906705003209414,"*",0.848922,"PPEF1","GO:0005829//cytosol","GO:0004721//phosphoprotein phosphatase activity;GO:0005506//iron ion binding;GO:0005509//calcium ion binding;GO:0004722//protein serine/threonine phosphatase activity;GO:0030145//manganese ion binding","GO:0006470//protein dephosphorylation;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0050906//detection of stimulus involved in sensory perception","K13807//serine/threonine-protein phosphatase with EF-hands [EC:3.1.3.16]","NP_689410.1//serine/threonine-protein phosphatase with EF-hands 1 isoform 1b [Homo sapiens];NP_006231.2//serine/threonine-protein phosphatase with EF-hands 1 isoform 1 [Homo sapiens];NP_689412.1//serine/threonine-protein phosphatase with EF-hands 1 isoform 3 [Homo sapiens]","1//3;2//1"]
[3224,2290,4.93,4.3,-0.197250986788451,0.420028598187887,"*",0.275698,"HOXC8","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0015630//microtubule cytoskeleton","GO:0003677//DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0009952//anterior/posterior pattern specification;GO:0030182//neuron differentiation;GO:0007275//multicellular organism development;GO:0006351//transcription, DNA-templated;GO:0048705//skeletal system morphogenesis","K09308//homeobox protein HoxB/C/D8","XP_022267180.1//uncharacterized protein LOC607625 [Canis lupus familiaris]","3//A2MP1"]
[10892,5046,5.58,4.87,-0.196343349746845,0.154716857682403,"*",0.0789856,"MALT1","GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0005730//nucleolus;GO:0043234//protein complex;GO:0005829//cytosol;GO:0032449//CBM complex;GO:0001650//fibrillar center;GO:0005886//plasma membrane","GO:0002020//protease binding;GO:0019209//kinase activator activity;GO:0008233//peptidase activity;GO:0042802//identical protein binding;GO:0004197//cysteine-type endopeptidase activity;GO:0004871//signal transducer activity;GO:0043621//protein self-association;GO:0004842//ubiquitin-protein transferase activity","GO:0009620//response to fungus;GO:0002237//response to molecule of bacterial origin;GO:0032743//positive regulation of interleukin-2 production;GO:0051168//nuclear export;GO:0045087//innate immune response;GO:0051259//protein oligomerization;GO:0050852//T cell receptor signaling pathway;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0007250//activation of NF-kappaB-inducing kinase activity;GO:0031398//positive regulation of protein ubiquitination;GO:0043066//negative regulation of apoptotic process;GO:0050870//positive regulation of T cell activation;GO:0050856//regulation of T cell receptor signaling pathway;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0042098//T cell proliferation;GO:0006508//proteolysis;GO:0006952//defense response;GO:0002726//positive regulation of T cell cytokine production;GO:0001923//B-1 B cell differentiation;GO:0042981//regulation of apoptotic process","K07369//mucosa-associated lymphoid tissue lymphoma translocation protein 1 [EC:3.4.22.-]","NP_006776.1//mucosa-associated lymphoid tissue lymphoma translocation protein 1 isoform a [Homo sapiens];NP_776216.1//mucosa-associated lymphoid tissue lymphoma translocation protein 1 isoform b [Homo sapiens]","3//A2MP1;2//1"]
[1947,3344,4.49,3.92,-0.195861790625939,0.344964531791908,"*",0.209216,"EFNB1","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0045121//membrane raft;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0045202//synapse;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0046875//ephrin receptor binding","GO:0001755//neural crest cell migration;GO:0042102//positive regulation of T cell proliferation;GO:0048013//ephrin receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0031295//T cell costimulation;GO:0007155//cell adhesion;GO:0009880//embryonic pattern specification;GO:0007411//axon guidance","K05463//ephrin-B","XP_009233224.1//PREDICTED: LOW QUALITY PROTEIN: ephrin-B1 [Pongo abelii]",4]
[9351,2050,25.12,21.95,-0.194615524468907,0.23411273822013,"*",0.1307596,"SLC9A3R2","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0012505//endomembrane system;GO:0005634//nucleus;GO:0005925//focal adhesion;GO:0016324//apical plasma membrane;GO:0005886//plasma membrane","GO:0032947//protein complex scaffold activity;GO:0008022//protein C-terminus binding;GO:0019902//phosphatase binding;GO:0005102//receptor binding;GO:0045296//cadherin binding;GO:0008013//beta-catenin binding","GO:0006461//protein complex assembly","K13358//Na(+)/H(+) exchange regulatory cofactor NHE-RF2","AAH14513.2//SLC9A3R2 protein, partial [Homo sapiens];XP_016879383.1//PREDICTED: Na(+)/H(+) exchange regulatory cofactor NHE-RF2 isoform X1 [Homo sapiens];XP_005590983.1//PREDICTED: Na(+)/H(+) exchange regulatory cofactor NHE-RF2 [Macaca fascicularis]","1//3;2//1;5"]
[9987,4155,47.98,41.94,-0.194106296196842,{"v":2.55583041464146e-05,"d":"2.56E-05"},"*",{"v":5.33278e-06,"d":"5.33E-06"},"HNRNPDL","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0030529//intracellular ribonucleoprotein complex;GO:0005829//cytosol;GO:0019013//viral nucleocapsid","GO:0008143//poly(A) binding;GO:0003697//single-stranded DNA binding;GO:0003723//RNA binding;GO:0003677//DNA binding;GO:0034046//poly(G) binding;GO:0003690//double-stranded DNA binding","GO:0006396//RNA processing;GO:0010468//regulation of gene expression;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0035722//interleukin-12-mediated signaling pathway","K13044//heterogeneous nuclear ribonucleoprotein A/B/D","NP_001193929.1//heterogeneous nuclear ribonucleoprotein D-like isoform b [Homo sapiens];NP_112740.1//heterogeneous nuclear ribonucleoprotein D-like isoform a [Homo sapiens]","1//3;3//A2MP1"]
[387263,4116,6.29,5.5,-0.193628398467267,0.166410205992964,"*",0.085872,"C6orf120","GO:0070062//extracellular exosome;GO:0035578//azurophil granule lumen;GO:0005576//extracellular region","NA","GO:0043312//neutrophil degranulation;GO:0006915//apoptotic process","K22197//BRG1-associated factor 45A","NP_001304271.1//UPF0669 protein C6orf120 isoform 2 precursor [Homo sapiens];XP_008971840.1//PREDICTED: LOW QUALITY PROTEIN: UPF0669 protein C6orf120 homolog [Pan paniscus]","1//3;2//1"]
[92667,2330,17.95,15.7,-0.193219284931424,0.0453098740853933,"*",0.01893348,"MGME1","GO:0005739//mitochondrion","GO:0008297//single-stranded DNA exodeoxyribonuclease activity;GO:0003677//DNA binding","GO:0006264//mitochondrial DNA replication;GO:0000002//mitochondrial genome maintenance;GO:0043504//mitochondrial DNA repair","K19465//mitochondrial genome maintenance exonuclease 1 [EC:3.1.-.-]","NP_001297267.1//mitochondrial genome maintenance exonuclease 1 isoform 1 precursor [Homo sapiens];NP_001297268.1//mitochondrial genome maintenance exonuclease 1 isoform 3 precursor [Homo sapiens];NP_443097.1//mitochondrial genome maintenance exonuclease 1 isoform 2 precursor [Homo sapiens]","1//3;3//A2MP1"]
[51702,3189,4.64,4.06,-0.192645077942396,0.364779258270106,"*",0.225732,"PADI3","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0042802//identical protein binding;GO:0005509//calcium ion binding;GO:0004668//protein-arginine deiminase activity","GO:0018101//protein citrullination;GO:0006325//chromatin organization;GO:0036414//histone citrullination","K01481//protein-arginine deiminase [EC:3.5.3.15]","NP_057317.2//protein-arginine deiminase type-3 [Homo sapiens]","2//1"]
[145389,1727,19.69,17.23,-0.192540409676605,0.154391552,"*",0.0787712,"SLC38A6","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0015171//amino acid transmembrane transporter activity","GO:0003333//amino acid transmembrane transport;GO:0006814//sodium ion transport","K14993//solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 6","NP_001166173.1//probable sodium-coupled neutral amino acid transporter 6 isoform 1 [Homo sapiens];NP_722518.2//probable sodium-coupled neutral amino acid transporter 6 isoform 2 [Homo sapiens]","1//3;2//1"]
[353116,2795,7.95,6.96,-0.191867554322989,0.106586181635087,"*",0.0503572,"RILPL1","GO:0005929//cilium;GO:0036064//ciliary basal body;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005813//centrosome;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0031267//small GTPase binding;GO:0051959//dynein light intermediate chain binding;GO:0046983//protein dimerization activity","GO:1903445//protein transport from ciliary membrane to plasma membrane;GO:0060271//cilium assembly;GO:0003382//epithelial cell morphogenesis;GO:1901214//regulation of neuron death","K20173//RILP-like protein 1","NP_847884.2//RILP-like protein 1 isoform 1 [Homo sapiens];NP_001306172.1//RILP-like protein 1 isoform 2 [Homo sapiens];NP_001306173.1//RILP-like protein 1 isoform 3 [Homo sapiens]","4;1//3"]
[339448,1705,22.77,19.94,-0.191468881738426,0.104253941192123,"*",0.049053,"C1orf174","GO:0005634//nucleus","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K12022//tripartite motif-containing protein 46;K11447//histone demethylase [EC:1.14.11.-];K01064//wingless-type MMTV integration site family, member 9","AAH35643.1//C1orf174 protein, partial [Homo sapiens]","2//1"]
[29902,1529,13.23,11.59,-0.190932495272205,0.275418542339016,"*",0.1587786,"FAM216A","NA","NA","NA","K06883//uncharacterized protein","XP_509366.3//PREDICTED: protein FAM216A, partial [Pan troglodytes]","2//1"]
[4901,3535,0.97,0.85,-0.190521906049426,0.762462227531122,"*",0.663324,"NRL","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:1990841//promoter-specific chromatin binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0043522//leucine zipper domain binding","GO:0007399//nervous system development;GO:0046548//retinal rod cell development;GO:0007601//visual perception;GO:0006366//transcription from RNA polymerase II promoter;GO:0045872//positive regulation of rhodopsin gene expression;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0050896//response to stimulus;GO:0007468//regulation of rhodopsin gene expression","K09038//neural retina-specific leucine zipper protein","XP_011535103.2//PREDICTED: neural retina-specific leucine zipper protein isoform X1 [Homo sapiens];XP_012322914.1//neural retina-specific leucine zipper protein isoform X1 [Aotus nancymaae];XP_017400145.1//PREDICTED: neural retina-specific leucine zipper protein [Cebus capucinus imitator];XP_011535108.2//PREDICTED: neural retina-specific leucine zipper protein isoform X3 [Homo sapiens]","4;1//3"]
[200205,7661,2.84,2.49,-0.189745187436601,0.236786098378257,"*",0.1325344,"IBA57","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0003723//RNA binding;GO:0016740//transferase activity","GO:0016226//iron-sulfur cluster assembly;GO:0006783//heme biosynthetic process","K22073//transferase CAF17, mitochondrial [EC:2.1.-.-]","NP_001010867.1//putative transferase CAF17, mitochondrial isoform 1 precursor [Homo sapiens];XP_011941595.1//PREDICTED: putative transferase CAF17, mitochondrial isoform X11 [Cercocebus atys]","1//3;3//A2MP1"]
[3178,1817,402.32,352.79,-0.189533790930036,{"v":3.75816120666014e-16,"d":"3.76E-16"},"*",{"v":2.40208e-17,"d":"2.40E-17"},"HNRNPA1","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0071013//catalytic step 2 spliceosome;GO:0005681//spliceosomal complex;GO:0005829//cytosol;GO:0030529//intracellular ribonucleoprotein complex;GO:1990826//nucleoplasmic periphery of the nuclear pore complex;GO:0019013//viral nucleocapsid","GO:0061752//telomeric repeat-containing RNA binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0098505//G-rich strand telomeric DNA binding;GO:0036310//annealing helicase activity;GO:0003697//single-stranded DNA binding;GO:1990825//sequence-specific mRNA binding;GO:0036002//pre-mRNA binding;GO:0019904//protein domain specific binding;GO:0035198//miRNA binding;GO:0033592//RNA strand annealing activity;GO:0008134//transcription factor binding;GO:0003727//single-stranded RNA binding","GO:0030324//lung development;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0042149//cellular response to glucose starvation;GO:0051028//mRNA transport;GO:0008584//male gonad development;GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0051168//nuclear export;GO:0032211//negative regulation of telomere maintenance via telomerase;GO:0035865//cellular response to potassium ion;GO:0016070//RNA metabolic process;GO:1903936//cellular response to sodium arsenite;GO:1904579//cellular response to thapsigargin;GO:0051170//nuclear import;GO:1904577//cellular response to tunicamycin;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0045760//positive regulation of action potential;GO:0010628//positive regulation of gene expression;GO:0019087//transformation of host cell by virus;GO:0008380//RNA splicing","K12741//heterogeneous nuclear ribonucleoprotein A1/A3","BAE40987.1//unnamed protein product [Mus musculus];ERE84424.1//heterogeneous nuclear ribonucleoprotein A1 [Cricetulus griseus]","3//A2MP1"]
[388121,2020,2.44,2.14,-0.189270351161739,0.61784137730164,"*",0.462124,"TNFAIP8L3","GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0008526//phosphatidylinositol transporter activity;GO:0035091//phosphatidylinositol binding","GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0048017//inositol lipid-mediated signaling;GO:0051897//positive regulation of protein kinase B signaling;GO:0015914//phospholipid transport;GO:0006644//phospholipid metabolic process;GO:0019216//regulation of lipid metabolic process;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0042981//regulation of apoptotic process","K12471//epsin;K15696//RING finger protein 113B;K17985//activating molecule in BECN1-regulated autophagy protein 1;K01064//wingless-type MMTV integration site family, member 9","NP_997264.2//tumor necrosis factor alpha-induced protein 8-like protein 3 isoform 1 [Homo sapiens];XP_003266971.2//PREDICTED: LOW QUALITY PROTEIN: tumor necrosis factor alpha-induced protein 8-like protein 3 [Nomascus leucogenys]","1//3;3//A2MP1"]
[25880,1465,4.98,4.37,-0.188512462567483,0.561794995236033,"*",0.40603,"TMEM186","GO:0016021//integral component of membrane;GO:0005739//mitochondrion","NA","NA","NA","NP_056236.2//transmembrane protein 186 [Homo sapiens]","3//A2MP1"]
[9330,4338,9.82,8.62,-0.188035155225595,0.0996036714745308,"*",0.0465158,"GTF3C3","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0005730//nucleolus;GO:0000127//transcription factor TFIIIC complex","GO:0003677//DNA binding","GO:0006359//regulation of transcription from RNA polymerase III promoter;GO:0042791//5S class rRNA transcription from RNA polymerase III type 1 promoter;GO:0042797//tRNA transcription from RNA polymerase III promoter;GO:0006351//transcription, DNA-templated;GO:0006383//transcription from RNA polymerase III promoter","K15201//general transcription factor 3C polypeptide 3 (transcription factor C subunit 4)","NP_001193703.1//general transcription factor 3C polypeptide 3 isoform 2 [Homo sapiens];NP_036218.1//general transcription factor 3C polypeptide 3 isoform 1 [Homo sapiens]","4;1//3"]
[51299,1574,0.41,0.36,-0.187627003175771,0.882334490780142,"*",0.817764,"NRN1","GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0030054//cell junction;GO:0046658//anchored component of plasma membrane;GO:0032281//AMPA glutamate receptor complex;GO:0045202//synapse;GO:0005886//plasma membrane;GO:0031225//anchored component of membrane","GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity","GO:0007399//nervous system development;GO:0006501//C-terminal protein lipidation;GO:1990138//neuron projection extension","K05726//breast cancer anti-estrogen resistance 1","NP_057672.1//neuritin isoform 1 precursor [Homo sapiens];NP_001265640.1//neuritin isoform 2 [Homo sapiens]","1//3;2//1"]
[7681,2744,0.99,0.87,-0.186413124230881,0.734254791066706,"*",0.625684,"MKRN3","GO:0030529//intracellular ribonucleoprotein complex","GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0016740//transferase activity","GO:0016567//protein ubiquitination","K15687//E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]","NP_005655.1//probable E3 ubiquitin-protein ligase makorin-3 [Homo sapiens]","3//A2MP1"]
[51606,2179,15.7,13.8,-0.186096292113458,0.150064872255834,"*",0.0760846,"ATP6V1H","GO:0005765//lysosomal membrane;GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0000221//vacuolar proton-transporting V-type ATPase, V1 domain;GO:0005886//plasma membrane","GO:0030234//enzyme regulator activity;GO:0046961//proton-transporting ATPase activity, rotational mechanism","GO:0016241//regulation of macroautophagy;GO:0008286//insulin receptor signaling pathway;GO:0034220//ion transmembrane transport;GO:0050690//regulation of defense response to virus by virus;GO:0090383//phagosome acidification;GO:0007035//vacuolar acidification;GO:0015991//ATP hydrolysis coupled proton transport;GO:0006897//endocytosis;GO:0033572//transferrin transport","K02144//V-type H+-transporting ATPase subunit H","NP_998784.1//V-type proton ATPase subunit H isoform 2 [Homo sapiens];NP_998785.1//V-type proton ATPase subunit H isoform 1 [Homo sapiens]","3//A2MP1;2//1"]
[253769,3063,2.66,2.34,-0.184917715917785,0.284373119913514,"*",0.1646708,"WDR27","GO:0005654//nucleoplasm","NA","NA","K22069//LYR motif-containing protein 4;K14963//COMPASS component SWD3","NP_001337552.1//WD repeat-containing protein 27 isoform 3 [Homo sapiens];NP_872358.4//WD repeat-containing protein 27 isoform 1 [Homo sapiens];NP_001189479.1//WD repeat-containing protein 27 isoform 2 [Homo sapiens];NP_001337553.1//WD repeat-containing protein 27 isoform 4 [Homo sapiens]","4;1//3"]
[11157,789,9.74,8.57,-0.184626567969842,0.567748674840269,"*",0.411648,"LSM6","NA","NA","NA","K12625//U6 snRNA-associated Sm-like protein LSm6","XP_008587467.1//PREDICTED: U6 snRNA-associated Sm-like protein LSm6 isoform X1 [Galeopterus variegatus]","2//1"]
[114884,4231,2.92,2.57,-0.184200009686139,0.419244710754843,"*",0.275026,"OSBPL10","GO:0005856//cytoskeleton;GO:0005829//cytosol","GO:0015485//cholesterol binding;GO:0001786//phosphatidylserine binding;GO:0005548//phospholipid transporter activity","GO:0036150//phosphatidylserine acyl-chain remodeling;GO:0006869//lipid transport","K20465//oxysterol-binding protein-related protein 9/10/11","NP_001167531.1//oxysterol-binding protein-related protein 10 isoform 2 [Homo sapiens];NP_060254.2//oxysterol-binding protein-related protein 10 isoform 1 [Homo sapiens]","1//3;4"]
[57591,4374,27.73,24.42,-0.183384416052075,1.39846247560976E-3,"*",0.000402012,"MKL1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0003779//actin binding;GO:0003713//transcription coactivator activity;GO:0001105//RNA polymerase II transcription coactivator activity;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0003785//actin monomer binding;GO:0003700//DNA binding transcription factor activity;GO:0043522//leucine zipper domain binding","GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0030036//actin cytoskeleton organization;GO:0051145//smooth muscle cell differentiation;GO:0010735//positive regulation of transcription via serum response element binding;GO:0030900//forebrain development;GO:0001764//neuron migration;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0031175//neuron projection development;GO:2001234//negative regulation of apoptotic signaling pathway","K03006//DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6];K17582//antigen KI-67;K13172//serine/arginine repetitive matrix protein 2","XP_016794708.1//PREDICTED: MKL/myocardin-like protein 1 isoform X2 [Pan troglodytes];NP_001305068.1//MKL/myocardin-like protein 1 isoform 4 [Homo sapiens];XP_016794707.1//PREDICTED: MKL/myocardin-like protein 1 isoform X1 [Pan troglodytes]","4;1//3"]
[79892,4277,29.13,25.66,-0.182984531050666,0.00240611731230546,"*",0.000725872,"MCMBP","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0042555//MCM complex;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0000790//nuclear chromatin","GO:0003682//chromatin binding","GO:0007062//sister chromatid cohesion;GO:0051301//cell division;GO:0006261//DNA-dependent DNA replication","K05700//vinculin","NP_079110.1//mini-chromosome maintenance complex-binding protein isoform 1 [Homo sapiens];XP_016872153.1//PREDICTED: mini-chromosome maintenance complex-binding protein isoform X4 [Homo sapiens];NP_001243307.1//mini-chromosome maintenance complex-binding protein isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[64801,1559,21.81,19.22,-0.182381433867,0.190190626228733,"*",0.1007746,"ARV1","GO:0005794//Golgi apparatus;GO:0032541//cortical endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0015248//sterol transporter activity","GO:0006665//sphingolipid metabolic process;GO:0032383//regulation of intracellular cholesterol transport;GO:0090181//regulation of cholesterol metabolic process;GO:0097036//regulation of plasma membrane sterol distribution;GO:0006695//cholesterol biosynthetic process;GO:0030301//cholesterol transport;GO:0008206//bile acid metabolic process","K21848//lipid intermediate transporter","NP_073623.1//protein ARV1 isoform 2 [Homo sapiens];NP_001333921.1//protein ARV1 isoform 1 [Homo sapiens]","1//3;2//1"]
[10477,1593,37.27,32.85,-0.182121448519158,0.0535195665544003,"*",0.02288,"UBE2E3","NA","NA","NA","K20217//ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]","XP_008136725.1//PREDICTED: ubiquitin-conjugating enzyme E2 E3 [Eptesicus fuscus];XP_021498997.1//ubiquitin-conjugating enzyme E2 E3 isoform X1 [Meriones unguiculatus]","1//3;3//A2MP1;2//1"]
[283337,4256,7.26,6.4,-0.181897643108388,0.180768522345635,"*",0.0947524,"ZNF740","NA","GO:0003676//nucleic acid binding","NA","K09228//KRAB domain-containing zinc finger protein","XP_013988087.1//PREDICTED: gastrula zinc finger protein XlCGF58.1-like isoform X2 [Salmo salar]","3//A2MP1"]
[83606,3518,27.27,24.06,-0.180678057739187,0.0102769524242424,"*",3.56676E-3,"GUCD1","NA","NA","NA","K01368//cathepsin S [EC:3.4.22.27];K11088//small nuclear ribonucleoprotein D3;K11447//histone demethylase [EC:1.14.11.-];K21125//mucin-5AC;K01064//wingless-type MMTV integration site family, member 9","AAH53529.1//C22orf13 protein, partial [Homo sapiens];NP_001271181.1//protein GUCD1 isoform b [Homo sapiens];NP_001271180.1//protein GUCD1 isoform a [Homo sapiens];NP_001271182.1//protein GUCD1 isoform c [Homo sapiens];BAG58044.1//unnamed protein product [Homo sapiens]","1//3;3//A2MP1"]
[8139,4544,0.85,0.75,-0.180572245641821,0.66026762938026,"*",0.540234,"GAN","GO:0005737//cytoplasm;GO:0031463//Cul3-RING ubiquitin ligase complex","NA","GO:0016567//protein ubiquitination;GO:0007010//cytoskeleton organization","K10453//kelch-like protein 16 (gigaxonin)","XP_016785723.1//PREDICTED: gigaxonin [Pan troglodytes]","3//A2MP1"]
[58516,3075,19.13,16.88,-0.180521969638927,0.0363267436989048,"*",0.0147431,"SINHCAF","NA","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K07560//D-tyrosyl-tRNA(Tyr) deacylase [EC:3.1.-.-];K11447//histone demethylase [EC:1.14.11.-];K09488//TNF receptor-associated protein 1;K20164//DENN domain-containing protein 5","XP_021777849.1//protein FAM60A isoform X1 [Papio anubis];XP_019592493.1//PREDICTED: protein FAM60A isoform X1 [Rhinolophus sinicus];XP_006986736.2//PREDICTED: protein FAM60A isoform X1 [Peromyscus maniculatus bairdii]","1//3;2//1"]
[84645,1777,1.54,1.36,-0.179323699444562,0.734308736757035,"*",0.625684,"C22orf23","NA","NA","NA","NA","XP_003264785.1//PREDICTED: UPF0193 protein EVG1 isoform X3 [Nomascus leucogenys];XP_012363215.1//PREDICTED: UPF0193 protein EVG1 isoform X1 [Nomascus leucogenys]","1//3;4"]
[10928,4368,17.5,15.46,-0.178814602794844,0.0251776129789303,"*",0.00972492,"RALBP1","GO:0016020//membrane;GO:0005829//cytosol;GO:0005622//intracellular","GO:0048365//Rac GTPase binding;GO:0017160//Ral GTPase binding;GO:0043492//ATPase activity, coupled to movement of substances;GO:0022857//transmembrane transporter activity;GO:0005096//GTPase activator activity;GO:0016887//ATPase activity","GO:0006810//transport;GO:0055085//transmembrane transport;GO:0007165//signal transduction;GO:0043547//positive regulation of GTPase activity;GO:0043087//regulation of GTPase activity;GO:0007264//small GTPase mediated signal transduction;GO:0006897//endocytosis;GO:0006935//chemotaxis;GO:0051056//regulation of small GTPase mediated signal transduction","K08773//RalA-binding protein 1","NP_006779.1//ralA-binding protein 1 [Homo sapiens]","3//A2MP1"]
[5337,6025,1.46,1.29,-0.178597303456763,0.610737518228509,"*",0.454096,"PLD1","GO:0016020//membrane;GO:0005765//lysosomal membrane;GO:0016324//apical plasma membrane;GO:0005622//intracellular;GO:0031902//late endosome membrane;GO:0048471//perinuclear region of cytoplasm;GO:0000139//Golgi membrane;GO:0005768//endosome;GO:0030139//endocytic vesicle;GO:0005794//Golgi apparatus;GO:0035579//specific granule membrane;GO:0005789//endoplasmic reticulum membrane;GO:0070821//tertiary granule membrane;GO:0005886//plasma membrane","GO:0004630//phospholipase D activity;GO:0070290//N-acylphosphatidylethanolamine-specific phospholipase D activity;GO:0035091//phosphatidylinositol binding","GO:0048017//inositol lipid-mediated signaling;GO:0016042//lipid catabolic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0032534//regulation of microvillus assembly;GO:0048870//cell motility;GO:0007264//small GTPase mediated signal transduction;GO:0043312//neutrophil degranulation;GO:0006935//chemotaxis;GO:0007265//Ras protein signal transduction","K01115//phospholipase D1/2 [EC:3.1.4.4]","NP_002653.1//phospholipase D1 isoform a [Homo sapiens];BAD93144.1//phospholipase D1 variant, partial [Homo sapiens]","4;2//1"]
[4215,4806,10.16,8.98,-0.178113052031019,0.0826698627071823,"*",0.037469,"MAP3K3","GO:0005829//cytosol;GO:0005622//intracellular;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0004709//MAP kinase kinase kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity","GO:0000165//MAPK cascade;GO:0007346//regulation of mitotic cell cycle;GO:0032147//activation of protein kinase activity;GO:0035556//intracellular signal transduction;GO:0001568//blood vessel development;GO:0046777//protein autophosphorylation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:1900745//positive regulation of p38MAPK cascade;GO:0042981//regulation of apoptotic process;GO:0031098//stress-activated protein kinase signaling cascade","K04421//mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]","NP_002392.2//mitogen-activated protein kinase kinase kinase 3 isoform 2 [Homo sapiens];NP_976226.1//mitogen-activated protein kinase kinase kinase 3 isoform 1 [Homo sapiens];NP_001317360.1//mitogen-activated protein kinase kinase kinase 3 isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[126295,1917,1.64,1.45,-0.177642914603149,0.650788005938144,"*",0.493978,"ZNF57","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_012291640.1//zinc finger protein 57 [Aotus nancymaae]","1//3;2//1"]
[10124,2990,8.91,7.88,-0.177229802065546,0.228837480949702,"*",0.1273118,"ARL4A","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0005525//GTP binding","GO:0007264//small GTPase mediated signal transduction;GO:0050873//brown fat cell differentiation","K07945//ADP-ribosylation factor-like protein 4","XP_003255929.2//PREDICTED: ADP-ribosylation factor-like protein 4A [Nomascus leucogenys]","4;1//3;3//A2MP1;2//1"]
[158038,13799,0.26,0.23,-0.176877762084079,0.647255753580779,"*",0.526184,"LINGO2","NA","NA","NA","K07523//netrin-G1 ligand;K16351//netrin-G2 ligand","XP_001505252.1//PREDICTED: leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 [Ornithorhynchus anatinus]","1//3;3//A2MP1;2//1"]
[57684,2008,1.4,1.24,-0.175086706558091,0.73418737800437,"*",0.63105,"ZBTB26","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0042802//identical protein binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein;K10505//zinc finger and BTB domain-containing protein 26","XP_014384383.1//PREDICTED: zinc finger and BTB domain-containing protein 26 isoform X1 [Myotis brandtii];XP_009186400.1//zinc finger and BTB domain-containing protein 26 isoform X1 [Papio anubis]","1//3;3//A2MP1"]
[653121,7273,5,4.43,-0.174621396107069,0.192218332280123,"*",0.1020656,"ZBTB8A","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K10495//zinc finger and BTB domain-containing protein 8","NP_001035531.2//zinc finger and BTB domain-containing protein 8A isoform 1 [Homo sapiens];NP_001278425.1//zinc finger and BTB domain-containing protein 8A isoform 2 [Homo sapiens]","1//3;2//1"]
[29964,1646,2.99,2.65,-0.174153124747544,0.643597175980883,"*",0.522686,"PRICKLE4","NA","NA","NA","K04511//prickle","XP_011928777.1//PREDICTED: prickle-like protein 4 isoform X2 [Cercocebus atys]",5]
[267,3475,28.59,25.35,-0.173524872740395,1.12530865854199E-3,"*",0.000317924,"AMFR","GO:0016020//membrane;GO:0030425//dendrite;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0044322//endoplasmic reticulum quality control compartment;GO:0048471//perinuclear region of cytoplasm;GO:0043025//neuronal cell body;GO:0030426//growth cone;GO:0043234//protein complex;GO:0005794//Golgi apparatus;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0036513//Derlin-1 retrotranslocation complex;GO:0005789//endoplasmic reticulum membrane","GO:0061630//ubiquitin protein ligase activity;GO:0004872//receptor activity;GO:0030674//protein binding, bridging;GO:0042802//identical protein binding;GO:0051087//chaperone binding;GO:1990381//ubiquitin-specific protease binding;GO:1904264//ubiquitin protein ligase activity involved in ERAD pathway;GO:0004842//ubiquitin-protein transferase activity;GO:0034450//ubiquitin-ubiquitin ligase activity;GO:1904288//BAT3 complex binding;GO:0046872//metal ion binding","GO:0070936//protein K48-linked ubiquitination;GO:1904380//endoplasmic reticulum mannose trimming;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0032092//positive regulation of protein binding;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0036503//ERAD pathway;GO:0051865//protein autoubiquitination;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0007611//learning or memory;GO:0000209//protein polyubiquitination;GO:0051259//protein oligomerization;GO:0006457//protein folding;GO:0007165//signal transduction;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0007568//aging;GO:0006928//movement of cell or subcellular component","K10636//autocrine motility factor receptor [EC:2.3.2.27]","NP_001135.3//E3 ubiquitin-protein ligase AMFR isoform c [Homo sapiens];XP_007991537.1//PREDICTED: E3 ubiquitin-protein ligase AMFR [Chlorocebus sabaeus]","1//3;5"]
[23247,6640,5.03,4.46,-0.173514689885222,0.180723168558117,"*",0.094706,"KIAA0556","GO:0005856//cytoskeleton;GO:0005615//extracellular space;GO:0042995//cell projection;GO:0005737//cytoplasm","NA","NA","K21125//mucin-5AC","EAW55743.1//KIAA0556 protein [Homo sapiens]","3//A2MP1"]
[51088,7350,11.5,10.2,-0.17306470897288,0.0117253818136558,"*",0.00412818,"KLHL5","GO:0005856//cytoskeleton;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0031463//Cul3-RING ubiquitin ligase complex","GO:0003779//actin binding","GO:0043687//post-translational protein modification;GO:0016567//protein ubiquitination","K10442//kelch-like protein 1/4/5","NP_057074.3//kelch-like protein 5 isoform 1 [Homo sapiens];XP_005262712.1//PREDICTED: kelch-like protein 5 isoform X2 [Homo sapiens];BAD92057.1//kelch-like 5 isoform 2 variant, partial [Homo sapiens];NP_950240.2//kelch-like protein 5 isoform 2 [Homo sapiens]","4;1//3;3//A2MP1;2//1"]
[84552,3847,3.29,2.92,-0.172119214855224,0.456342737918216,"*",0.30739,"PARD6G","GO:0043234//protein complex;GO:0005829//cytosol;GO:0005923//bicellular tight junction;GO:0005886//plasma membrane","NA","GO:0070830//bicellular tight junction assembly;GO:0007163//establishment or maintenance of cell polarity;GO:0051301//cell division;GO:0007049//cell cycle","K06093//partitioning defective protein 6","NP_115899.1//partitioning defective 6 homolog gamma [Homo sapiens]","3//A2MP1"]
[10732,2657,5.78,5.13,-0.172110666893625,0.429009075011854,"*",0.283204,"TCFL5","GO:0005634//nucleus;GO:0001673//male germ cell nucleus","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0046983//protein dimerization activity","GO:0030154//cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0042127//regulation of cell proliferation;GO:0007283//spermatogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007275//multicellular organism development;GO:0045595//regulation of cell differentiation","K09092//transcription factor-like 5","NP_001288655.1//transcription factor-like 5 protein isoform 2 [Homo sapiens];NP_006593.2//transcription factor-like 5 protein isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[54784,2138,7.69,6.83,-0.171098019671736,0.393422718538167,"*",0.250698,"ALKBH4","GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0030496//midbody;GO:0070938//contractile ring","GO:0003779//actin binding;GO:0046872//metal ion binding;GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;GO:0032451//demethylase activity","GO:0036090//cleavage furrow ingression;GO:0031032//actomyosin structure organization;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0070988//demethylation;GO:0006482//protein demethylation","K10766//alkylated DNA repair protein alkB homolog 4 [EC:1.14.11.-]","XP_017713105.1//PREDICTED: alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 [Rhinopithecus bieti]","3//A2MP1"]
[8635,1250,8.8,7.82,-0.170334916217307,0.511819707045291,"*",0.35655,"RNASET2","GO:0070062//extracellular exosome;GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0035578//azurophil granule lumen;GO:0043202//lysosomal lumen;GO:0005576//extracellular region;GO:0005764//lysosome","GO:0003723//RNA binding;GO:0033897//ribonuclease T2 activity;GO:0004540//ribonuclease activity","GO:0006401//RNA catabolic process;GO:0043312//neutrophil degranulation","K01166//ribonuclease T2 [EC:3.1.27.1]","NP_003721.2//ribonuclease T2 precursor [Homo sapiens]",4]
[5264,1620,17.8,15.82,-0.170127641380968,0.233585366502242,"*",0.1304358,"PHYH","GO:0005782//peroxisomal matrix;GO:0005777//peroxisome;GO:0005739//mitochondrion","GO:0031406//carboxylic acid binding;GO:0048244//phytanoyl-CoA dioxygenase activity;GO:0048037//cofactor binding;GO:0031418//L-ascorbic acid binding;GO:0008198//ferrous iron binding","GO:0001561//fatty acid alpha-oxidation;GO:0006720//isoprenoid metabolic process;GO:0006103//2-oxoglutarate metabolic process;GO:0097089//methyl-branched fatty acid metabolic process","K00477//phytanoyl-CoA hydroxylase [EC:1.14.11.18]","NP_006205.1//phytanoyl-CoA dioxygenase, peroxisomal isoform a precursor [Homo sapiens];EAW86295.1//phytanoyl-CoA 2-hydroxylase, isoform CRA_b [Homo sapiens];EAW86294.1//phytanoyl-CoA 2-hydroxylase, isoform CRA_a [Homo sapiens];NP_001310012.1//phytanoyl-CoA dioxygenase, peroxisomal isoform d precursor [Homo sapiens];NP_001310011.1//phytanoyl-CoA dioxygenase, peroxisomal isoform c precursor [Homo sapiens];EHH18893.1//hypothetical protein EGK_19462, partial [Macaca mulatta]","1//3;3//A2MP1"]
[6489,9737,0.27,0.24,-0.169925001442312,0.732964755956785,"*",0.620088,"ST8SIA1","GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0008373//sialyltransferase activity;GO:0003828//alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity","GO:0006486//protein glycosylation;GO:0006665//sphingolipid metabolic process;GO:0034605//cellular response to heat;GO:0008284//positive regulation of cell proliferation","K03371//alpha-N-acetyl-neuraminate alpha-2,8-sialyltransferase (sialyltransferase 8A) [EC:2.4.99.8]","XP_016778110.1//PREDICTED: alpha-N-acetylneuraminide alpha-2,8-sialyltransferase isoform X1 [Pan troglodytes];XP_001099511.1//PREDICTED: alpha-N-acetylneuraminide alpha-2,8-sialyltransferase isoform X1 [Macaca mulatta]","1//3;3//A2MP1"]
[4045,9508,0.18,0.16,-0.169925001442312,0.749359013310185,"*",0.6485,"LSAMP","GO:0005886//plasma membrane;GO:0031225//anchored component of membrane","NA","GO:0007155//cell adhesion;GO:0035641//locomotory exploration behavior","K06772//limbic system-associated membrane protein","XP_006905544.1//PREDICTED: limbic system-associated membrane protein isoform X1 [Pteropus alecto];XP_008841101.1//PREDICTED: limbic system-associated membrane protein isoform X4 [Nannospalax galili]","1//3;4"]
[7515,2102,28.92,25.71,-0.169737942117462,0.0662001395348837,"*",0.029047,"XRCC1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000784//nuclear chromosome, telomeric region;GO:0005730//nucleolus;GO:0070522//ERCC4-ERCC1 complex;GO:0000790//nuclear chromatin","GO:1990599//3' overhang single-stranded DNA endodeoxyribonuclease activity;GO:0003684//damaged DNA binding;GO:0003909//DNA ligase activity;GO:0032356//oxidized DNA binding;GO:0019899//enzyme binding","GO:0006284//base-excision repair;GO:0021766//hippocampus development;GO:0006283//transcription-coupled nucleotide-excision repair;GO:1903518//positive regulation of single strand break repair;GO:0010836//negative regulation of protein ADP-ribosylation;GO:1904877//positive regulation of DNA ligase activity;GO:0010033//response to organic substance;GO:0006288//base-excision repair, DNA ligation;GO:1905765//negative regulation of protection from non-homologous end joining at telomere;GO:0000012//single strand break repair;GO:0042493//response to drug;GO:0061819//telomeric DNA-containing double minutes formation;GO:0001666//response to hypoxia;GO:0006297//nucleotide-excision repair, DNA gap filling;GO:0000724//double-strand break repair via homologous recombination;GO:0006303//double-strand break repair via nonhomologous end joining","K10803//DNA-repair protein XRCC1","BAD92018.1//X-ray repair cross complementing protein 1 variant, partial [Homo sapiens]","2//1"]
[55589,2879,3.35,2.98,-0.168848764882973,0.183985109,"*",0.0967494,"BMP2K","GO:0016607//nuclear speck;GO:0005737//cytoplasm","GO:0035612//AP-2 adaptor complex binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0019208//phosphatase regulator activity","GO:0030500//regulation of bone mineralization;GO:0045747//positive regulation of Notch signaling pathway;GO:2000369//regulation of clathrin-dependent endocytosis;GO:0006468//protein phosphorylation","K08854//BMP2 inducible kinase [EC:2.7.11.1]","XP_011797184.1//PREDICTED: BMP-2-inducible protein kinase [Colobus angolensis palliatus];NP_942595.1//BMP-2-inducible protein kinase isoform a [Homo sapiens]","1//3;3//A2MP1"]
[9757,8490,26.25,23.36,-0.16827714856083,0.000122823449772788,"*",{"v":2.87644e-05,"d":"2.88E-05"},"KMT2B","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0035097//histone methyltransferase complex","GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0042800//histone methyltransferase activity (H3-K4 specific);GO:0003700//DNA binding transcription factor activity;GO:0018024//histone-lysine N-methyltransferase activity","GO:0016458//gene silencing;GO:0051569//regulation of histone H3-K4 methylation;GO:0009994//oocyte differentiation;GO:0048096//chromatin-mediated maintenance of transcription;GO:0006351//transcription, DNA-templated;GO:0051568//histone H3-K4 methylation;GO:0045652//regulation of megakaryocyte differentiation;GO:0030728//ovulation;GO:0001541//ovarian follicle development;GO:0007613//memory;GO:0080182//histone H3-K4 trimethylation","K14959//histone-lysine N-methyltransferase MLL4 [EC:2.1.1.43]","NP_055542.1//histone-lysine N-methyltransferase 2B [Homo sapiens]","2//1"]
[221060,1785,88.84,79.07,-0.168078968234821,0.00170096453892216,"*",0.000497916,"C10orf111","GO:0016021//integral component of membrane","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K11447//histone demethylase [EC:1.14.11.-];K00134//glyceraldehyde 3-phosphate dehydrogenase [EC:1.2.1.12];K01064//wingless-type MMTV integration site family, member 9","EAW86242.1//hCG2017590 [Homo sapiens]","1//3"]
[55164,2861,8.22,7.32,-0.167294745397641,0.309482910190275,"*",0.1832796,"SHQ1","GO:0005654//nucleoplasm;GO:0005829//cytosol","NA","GO:1904874//positive regulation of telomerase RNA localization to Cajal body;GO:2000233//negative regulation of rRNA processing;GO:0043065//positive regulation of apoptotic process;GO:0022618//ribonucleoprotein complex assembly","K14764//protein SHQ1","AAH47879.1//SHQ1 homolog (S. cerevisiae) [Homo sapiens]","2//1"]
[1773,3108,1.92,1.71,-0.167109985835258,0.630008110869565,"*",0.507982,"DNASE1","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005576//extracellular region","GO:0003779//actin binding;GO:0004530//deoxyribonuclease I activity","GO:0006308//DNA catabolic process;GO:0006915//apoptotic process","K11994//deoxyribonuclease-1 [EC:3.1.21.1]","NP_005214.2//deoxyribonuclease-1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[11060,3905,13.21,11.77,-0.166516146208384,0.0132860963388169,"*",0.00475252,"WWP2","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0000151//ubiquitin ligase complex;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0001190//transcriptional activator activity, RNA polymerase II transcription factor binding;GO:0061630//ubiquitin protein ligase activity;GO:0008134//transcription factor binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity","GO:0070534//protein K63-linked ubiquitination;GO:0016567//protein ubiquitination;GO:0043433//negative regulation of DNA binding transcription factor activity;GO:0051224//negative regulation of protein transport;GO:0010629//negative regulation of gene expression;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0051865//protein autoubiquitination;GO:0042391//regulation of membrane potential;GO:0045892//negative regulation of transcription, DNA-templated;GO:0034765//regulation of ion transmembrane transport;GO:0006858//extracellular transport;GO:0032410//negative regulation of transporter activity;GO:1901016//regulation of potassium ion transmembrane transporter activity;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0006464//cellular protein modification process;GO:0046718//viral entry into host cell","K05630//atrophin-1 interacting protein 2 (WW domain containing E3 ubiquitin protein ligase 2) [EC:2.3.2.26]","NP_008945.2//NEDD4-like E3 ubiquitin-protein ligase WWP2 isoform WWP2-FL [Homo sapiens]","4;1//3;2//1"]
[84259,12741,3.03,2.7,-0.16635838642212,0.168559257198208,"*",0.0871498,"DCUN1D5","GO:0000151//ubiquitin ligase complex","GO:0032182//ubiquitin-like protein binding;GO:0097602//cullin family protein binding;GO:0031624//ubiquitin conjugating enzyme binding","GO:0045116//protein neddylation;GO:0051443//positive regulation of ubiquitin-protein transferase activity","K17824//DCN1-like protein 4/5","XP_019467790.1//PREDICTED: DCN1-like protein 5 isoform X2 [Meleagris gallopavo];XP_008147432.1//PREDICTED: DCN1-like protein 5 isoform X1 [Eptesicus fuscus];NP_115675.1//DCN1-like protein 5 isoform a [Homo sapiens]","1//3;3//A2MP1"]
[259,1450,1.57,1.4,-0.165337731946661,0.782893094428236,"*",0.688744,"AMBP","GO:0043231//intracellular membrane-bounded organelle;GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0009986//cell surface;GO:0072562//blood microparticle;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0020037//heme binding;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0019855//calcium channel inhibitor activity;GO:0019862//IgA binding;GO:0042803//protein homodimerization activity;GO:0036094//small molecule binding;GO:0046904//calcium oxalate binding","GO:0007565//female pregnancy;GO:0016032//viral process;GO:0018298//protein-chromophore linkage;GO:0030163//protein catabolic process;GO:0042167//heme catabolic process;GO:0007155//cell adhesion;GO:0050777//negative regulation of immune response;GO:0046329//negative regulation of JNK cascade;GO:0006898//receptor-mediated endocytosis","K03909//tissue factor pathway inhibitor","NP_001624.1//protein AMBP preproprotein [Homo sapiens]","3//A2MP1"]
[8622,4260,1.02,0.91,-0.164630701772799,0.536938395857105,"*",0.382956,"PDE8B","GO:0005829//cytosol","GO:0046872//metal ion binding;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0004115//3',5'-cyclic-AMP phosphodiesterase activity","GO:0009187//cyclic nucleotide metabolic process;GO:0006198//cAMP catabolic process;GO:0007165//signal transduction;GO:0046676//negative regulation of insulin secretion","K18437//high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:3.1.4.53]","NP_001025025.1//high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform 2 [Homo sapiens];NP_001336680.1//high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform 9 [Homo sapiens];NP_001025024.1//high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform 4 [Homo sapiens];NP_001336681.1//high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform 10 [Homo sapiens];NP_001025022.1//high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform 3 [Homo sapiens];NP_001336677.1//high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform 6 [Homo sapiens];NP_001336679.1//high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform 8 [Homo sapiens];NP_001025023.1//high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform 5 [Homo sapiens];NP_003710.1//high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform 1 [Homo sapiens];NP_001336678.1//high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform 7 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[79709,3724,48.71,43.48,-0.163866042813139,0.000901408025276461,"*",0.00025004,"COLGALT1","NA","GO:0016740//transferase activity","NA","K11703//collagen beta-1,O-galactosyltransferase [EC:2.4.1.50]","XP_003123541.1//procollagen galactosyltransferase 1 [Sus scrofa]","3//A2MP1"]
[51643,1878,11.86,10.59,-0.163401420553667,0.308897140499365,"*",0.182778,"TMBIM4","GO:0005795//Golgi stack;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","NA","GO:0050848//regulation of calcium-mediated signaling;GO:0043066//negative regulation of apoptotic process;GO:0006915//apoptotic process","K06890//uncharacterized protein","XP_011784644.1//PREDICTED: protein lifeguard 4 isoform X1 [Colobus angolensis palliatus];NP_001269539.1//protein lifeguard 4 isoform d [Homo sapiens];NP_001269535.1//protein lifeguard 4 isoform a [Homo sapiens]","1//3;3//A2MP1"]
[9026,4314,5.25,4.69,-0.162729500038109,0.444797912457912,"*",0.29772,"HIP1R","GO:0005938//cell cortex;GO:0016324//apical plasma membrane;GO:0032587//ruffle membrane;GO:0043025//neuronal cell body;GO:0005829//cytosol;GO:0030665//clathrin-coated vesicle membrane;GO:0005739//mitochondrion;GO:0043197//dendritic spine;GO:0005856//cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0032839//dendrite cytoplasm;GO:0030136//clathrin-coated vesicle;GO:0014069//postsynaptic density;GO:0048471//perinuclear region of cytoplasm;GO:0097060//synaptic membrane;GO:0005905//clathrin-coated pit","GO:0051015//actin filament binding;GO:0030276//clathrin binding;GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0035091//phosphatidylinositol binding;GO:0003779//actin binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0080025//phosphatidylinositol-3,5-bisphosphate binding;GO:0035615//clathrin adaptor activity;GO:0017124//SH3 domain binding;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding;GO:0032051//clathrin light chain binding","GO:0030100//regulation of endocytosis;GO:0032956//regulation of actin cytoskeleton organization;GO:0032092//positive regulation of protein binding;GO:0043065//positive regulation of apoptotic process;GO:0055123//digestive system development;GO:0048268//clathrin coat assembly;GO:0045742//positive regulation of epidermal growth factor receptor signaling pathway;GO:0060453//regulation of gastric acid secretion;GO:0034316//negative regulation of Arp2/3 complex-mediated actin nucleation;GO:0072583//clathrin-dependent endocytosis;GO:2000588//positive regulation of platelet-derived growth factor receptor-beta signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0006915//apoptotic process;GO:0061024//membrane organization;GO:0030837//negative regulation of actin filament polymerization;GO:1901030//positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway;GO:0006898//receptor-mediated endocytosis;GO:2000369//regulation of clathrin-dependent endocytosis;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0050821//protein stabilization;GO:1905445//positive regulation of clathrin coat assembly","K20040//huntingtin-interacting protein 1-related protein","NP_003950.1//huntingtin-interacting protein 1-related protein isoform 1 [Homo sapiens];NP_001290028.1//huntingtin-interacting protein 1-related protein isoform 3 [Homo sapiens];NP_001290026.1//huntingtin-interacting protein 1-related protein isoform 2 [Homo sapiens]","1//3;2//1"]
[314,2696,1.6,1.43,-0.162056758108973,0.679264152144264,"*",0.56122,"AOC2","GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0009055//electron transfer activity;GO:0052594//aminoacetone:oxygen oxidoreductase(deaminating) activity;GO:0008131//primary amine oxidase activity;GO:0005507//copper ion binding;GO:0048038//quinone binding;GO:0052596//phenethylamine:oxygen oxidoreductase (deaminating) activity;GO:0052595//aliphatic-amine oxidase activity;GO:0052593//tryptamine:oxygen oxidoreductase (deaminating) activity","GO:0006805//xenobiotic metabolic process;GO:0007601//visual perception;GO:0009308//amine metabolic process;GO:0006584//catecholamine metabolic process","K00276//primary-amine oxidase [EC:1.4.3.21]","NP_033720.2//retina-specific copper amine oxidase isoform b precursor [Homo sapiens];NP_001149.2//retina-specific copper amine oxidase isoform a precursor [Homo sapiens]","4;3//A2MP1"]
[7710,6914,0.85,0.76,-0.161463422694116,0.629959200993712,"*",0.507982,"ZNF154","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","ELK17771.1//Zinc finger protein 551 [Pteropus alecto]","2//1"]
[4645,9520,1.42,1.27,-0.161062432732516,0.480133050838142,"*",0.328134,"MYO5B","GO:0070062//extracellular exosome;GO:0045179//apical cortex;GO:0043234//protein complex;GO:0016459//myosin complex;GO:0030659//cytoplasmic vesicle membrane","GO:0003779//actin binding;GO:0005524//ATP binding;GO:0003774//motor activity;GO:0000146//microfilament motor activity;GO:0005516//calmodulin binding;GO:0017137//Rab GTPase binding","GO:0032439//endosome localization;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0003091//renal water homeostasis","K10357//myosin V","NP_001073936.1//unconventional myosin-Vb [Homo sapiens]","2//1"]
[30846,3601,95.41,85.35,-0.160749330947713,{"v":4.0702452470024e-06,"d":"4.07E-06"},"*",{"v":7.43774E-7,"d":"7.44E-07"},"EHD2","GO:0070062//extracellular exosome;GO:0010008//endosome membrane;GO:0005634//nucleus;GO:0015630//microtubule cytoskeleton;GO:0019898//extrinsic component of membrane;GO:0048471//perinuclear region of cytoplasm;GO:0045171//intercellular bridge;GO:0055038//recycling endosome membrane;GO:0005901//caveola;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0019904//protein domain specific binding;GO:0016787//hydrolase activity;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0005509//calcium ion binding;GO:0005525//GTP binding;GO:0003676//nucleic acid binding","GO:0072659//protein localization to plasma membrane;GO:0007596//blood coagulation;GO:2001137//positive regulation of endocytic recycling;GO:0030866//cortical actin cytoskeleton organization;GO:0006897//endocytosis;GO:0032456//endocytic recycling;GO:0097320//plasma membrane tubulation;GO:1901741//positive regulation of myoblast fusion","K12469//EH domain-containing protein 2","NP_055416.2//EH domain-containing protein 2 [Homo sapiens]","3//A2MP1"]
[117584,4137,21.3,19.06,-0.160305311203259,0.0308360763992419,"*",0.01222324,"RFFL","NA","NA","NA","K20804//E3 ubiquitin-protein ligase RNF34 [EC:2.3.2.27]","XP_004441925.2//PREDICTED: E3 ubiquitin-protein ligase rififylin isoform X1 [Ceratotherium simum simum]","1//3"]
[10090,4396,2.48,2.22,-0.159780444036769,0.549709416768346,"*",0.394852,"UST","GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0008146//sulfotransferase activity","GO:0030010//establishment of cell polarity;GO:0030208//dermatan sulfate biosynthetic process;GO:0006477//protein sulfation;GO:0050770//regulation of axonogenesis","K03193//dermatan/chondrotin sulfate uronyl 2-O-sulfotransferase UST [EC:2.8.2.-]","NP_005706.1//uronyl 2-sulfotransferase [Homo sapiens]","2//1"]
[8526,7784,1.82,1.63,-0.159066485967619,0.491859184215312,"*",0.338642,"DGKE","GO:0016020//membrane;GO:0005634//nucleus;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0004143//diacylglycerol kinase activity;GO:0003951//NAD+ kinase activity;GO:0046872//metal ion binding;GO:0005524//ATP binding;GO:0016301//kinase activity","GO:0008654//phospholipid biosynthetic process;GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0030168//platelet activation;GO:0035556//intracellular signal transduction;GO:0046834//lipid phosphorylation","K00901//diacylglycerol kinase (ATP) [EC:2.7.1.107]","XP_011523696.1//PREDICTED: diacylglycerol kinase epsilon isoform X2 [Homo sapiens]","2//1"]
[22832,5119,0.48,0.43,-0.158697746019058,0.794152426534933,"*",0.704466,"CEP162","GO:0005814//centriole;GO:0005879//axonemal microtubule;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005819//spindle;GO:0005813//centrosome","NA","GO:0060271//cilium assembly;GO:0097711//ciliary basal body-plasma membrane docking","K16809//protein QN1","NP_055710.2//centrosomal protein of 162 kDa isoform a [Homo sapiens]","1//3;3//A2MP1"]
[10536,2690,12.51,11.21,-0.158295511360393,0.227810106936937,"*",0.1266404,"P3H3","GO:0005783//endoplasmic reticulum;GO:1902494//catalytic complex","GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0019797//procollagen-proline 3-dioxygenase activity;GO:0005506//iron ion binding;GO:0031418//L-ascorbic acid binding","GO:0032963//collagen metabolic process;GO:0017185//peptidyl-lysine hydroxylation;GO:0008285//negative regulation of cell proliferation;GO:0032964//collagen biosynthetic process","K08440//G protein-coupled receptor 162;K08134//leucine proline-enriched proteoglycan (leprecan)","XP_015006419.1//PREDICTED: prolyl 3-hydroxylase 3 [Macaca mulatta]",4]
[55139,2521,6.97,6.25,-0.157302466318974,0.36753430989899,"*",0.227782,"ANKZF1","GO:0016020//membrane;GO:0036266//Cdc48p-Npl4p-Vms1p AAA ATPase complex;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0003676//nucleic acid binding","GO:0072671//mitochondria-associated ubiquitin-dependent protein catabolic process;GO:0071630//nuclear protein quality control by the ubiquitin-proteasome system;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0070301//cellular response to hydrogen peroxide","NA","NP_060559.2//ankyrin repeat and zinc finger domain-containing protein 1 isoform 1 [Homo sapiens];XP_005246720.1//PREDICTED: ankyrin repeat and zinc finger domain-containing protein 1 isoform X2 [Homo sapiens]","1//3;2//1"]
[442213,3268,3.78,3.39,-0.157100961084729,0.515887883818915,"*",0.360256,"PTCHD4","GO:0016021//integral component of membrane","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K12385//Niemann-Pick C1 protein;K07560//D-tyrosyl-tRNA(Tyr) deacylase [EC:3.1.-.-];K16506//protocadherin Fat 1/2/3;K14461//Niemann-Pick C1-like protein 1;K04487//cysteine desulfurase [EC:2.8.1.7]","NP_001013754.3//patched domain-containing protein 4 isoform 1 [Homo sapiens];NP_997382.2//patched domain-containing protein 4 isoform 2 [Homo sapiens]","3//A2MP1;2//1"]
[54884,3328,14.9,13.37,-0.156312865256171,0.136385062890232,"*",0.0678254,"RETSAT","GO:0016020//membrane;GO:0031965//nuclear membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005640//nuclear outer membrane","GO:0051786//all-trans-retinol 13,14-reductase activity;GO:0016491//oxidoreductase activity","GO:0042572//retinol metabolic process;GO:0055114//oxidation-reduction process","K09516//all-trans-retinol 13,14-reductase [EC:1.3.99.23]","NP_060220.3//all-trans-retinol 13,14-reductase precursor [Homo sapiens]","3//A2MP1"]
[10552,1623,63.29,56.81,-0.155832664760925,0.0243124020471162,"*",0.0093679,"ARPC1A","GO:0070062//extracellular exosome;GO:0005885//Arp2/3 protein complex;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0036195//muscle cell projection membrane","GO:0051015//actin filament binding;GO:0003779//actin binding","GO:0034314//Arp2/3 complex-mediated actin nucleation;GO:0030036//actin cytoskeleton organization;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0048013//ephrin receptor signaling pathway;GO:0061024//membrane organization","K05757//actin related protein 2/3 complex, subunit 1A/1B","NP_001177925.1//actin-related protein 2/3 complex subunit 1A isoform 2 [Homo sapiens];BAD92296.1//actin related protein 2/3 complex subunit 1A variant, partial [Homo sapiens]","1//3;3//A2MP1"]
[81575,4752,0.59,0.53,-0.154722594798642,0.733973547400612,"*",0.63105,"APOLD1","GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0008289//lipid binding","GO:0030154//cell differentiation;GO:0001525//angiogenesis;GO:0006869//lipid transport;GO:0042118//endothelial cell activation;GO:0045601//regulation of endothelial cell differentiation;GO:0042157//lipoprotein metabolic process;GO:0001666//response to hypoxia","K14777//ATP-dependent RNA helicase DDX47/RRP3 [EC:3.6.4.13];K14480//apolipoprotein L","AAH42478.1//APOLD1 protein, partial [Homo sapiens];NP_110444.3//apolipoprotein L domain-containing protein 1 isoform 2 [Homo sapiens]","1//3;2//1"]
[54584,1537,7.09,6.37,-0.154492254983216,0.582489055788842,"*",0.425508,"GNB1L","GO:0009898//cytoplasmic side of plasma membrane;GO:0005737//cytoplasm","NA","GO:0007186//G-protein coupled receptor signaling pathway;GO:0035176//social behavior;GO:0035556//intracellular signal transduction","K19760//dynein assembly factor with WDR repeat domains 1;K18643//katanin p80 WD40 repeat-containing subunit B1","NP_443730.1//guanine nucleotide-binding protein subunit beta-like protein 1 [Homo sapiens]","2//1"]
[79912,4245,8.82,7.93,-0.153457789853542,0.259216621505376,"*",0.1478966,"PYROXD1","GO:0005634//nucleus;GO:0030017//sarcomere","GO:0016491//oxidoreductase activity","GO:0034599//cellular response to oxidative stress","K10899//ATP-dependent DNA helicase Q1 [EC:3.6.4.12];K16174//small subunit ribosomal protein S18b, mitochondrial","NP_079130.2//pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 isoform 1 [Homo sapiens]","1//3;4"]
[81614,3111,42.26,38.01,-0.152913742072975,0.00288626225509372,"*",0.000886802,"NIPA2","GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005769//early endosome","GO:0015095//magnesium ion transmembrane transporter activity","GO:0015693//magnesium ion transport","K19364//magnesium transporter NIPA1","NP_001008894.1//magnesium transporter NIPA2 isoform b [Homo sapiens];NP_001008860.1//magnesium transporter NIPA2 isoform a [Homo sapiens]","6;1//3;2//1"]
[131076,734,26.45,23.8,-0.152306148806082,0.426182858283433,"*",0.280698,"CCDC58","GO:0005739//mitochondrion","NA","NA","K16741//alstrom syndrome protein 1","NP_001295255.1//coiled-coil domain-containing protein 58 isoform 2 [Homo sapiens];XP_004873654.2//coiled-coil domain-containing protein 58 isoform X1 [Heterocephalus glaber]","1//3;3//A2MP1"]
[7718,2411,0.7,0.63,-0.15200309344505,0.836479341004617,"*",0.759974,"ZNF165","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","XP_006215316.1//PREDICTED: zinc finger protein 165 [Vicugna pacos]","3//A2MP1"]
[246330,2634,6.7,6.03,-0.15200309344505,0.51640819360043,"*",0.360684,"PELI3","GO:0005829//cytosol","GO:0061630//ubiquitin protein ligase activity;GO:0004674//protein serine/threonine kinase activity;GO:0016874//ligase activity","GO:0070534//protein K63-linked ubiquitination;GO:0010804//negative regulation of tumor necrosis factor-mediated signaling pathway;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:0008063//Toll signaling pathway;GO:0006955//immune response","K11964//pellino [EC:2.3.2.27]","NP_001091980.1//E3 ubiquitin-protein ligase pellino homolog 3 isoform 2 [Homo sapiens];OWK17375.1//hypothetical protein Celaphus_00013231, partial [Cervus elaphus hippelaphus];NP_659502.2//E3 ubiquitin-protein ligase pellino homolog 3 isoform 1 [Homo sapiens];NP_001230064.1//E3 ubiquitin-protein ligase pellino homolog 3 isoform 3 [Homo sapiens]","1//3;2//1"]
[1500,5804,47.28,42.58,-0.151054085725239,{"v":6.80345100038745e-07,"d":"6.80E-07"},"*",{"v":1.099268E-7,"d":"1.10E-07"},"CTNND1","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005915//zonula adherens;GO:0030027//lamellipodium;GO:0005737//cytoplasm;GO:0030496//midbody;GO:0030426//growth cone;GO:0005911//cell-cell junction;GO:0005829//cytosol;GO:0043197//dendritic spine;GO:0005886//plasma membrane","GO:0005102//receptor binding;GO:0019901//protein kinase binding;GO:0045296//cadherin binding","GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0007155//cell adhesion;GO:0034332//adherens junction organization;GO:0006355//regulation of transcription, DNA-templated;GO:0035635//entry of bacterium into host cell;GO:0016055//Wnt signaling pathway;GO:0006351//transcription, DNA-templated;GO:0007420//brain development","K05690//catenin (cadherin-associated protein), delta 1","NP_001078927.1//catenin delta-1 isoform 1ABC [Homo sapiens];NP_001078928.1//catenin delta-1 isoform 1AB [Homo sapiens];NP_001193814.1//catenin delta-1 isoform 1AC [Homo sapiens];NP_001193812.1//catenin delta-1 isoform 2ABC [Homo sapiens];XP_007996293.1//PREDICTED: catenin delta-1 isoform X8 [Chlorocebus sabaeus];NP_001078929.1//catenin delta-1 isoform 1A [Homo sapiens];NP_001193817.1//catenin delta-1 isoform 2A [Homo sapiens];NP_001322.1//catenin delta-1 isoform 1B [Homo sapiens];NP_001193813.1//catenin delta-1 isoform 2AC [Homo sapiens]","1//3;2//1"]
[60412,4203,13.97,12.59,-0.150053737690447,0.117648843834901,"*",0.0563866,"EXOC4","GO:0016020//membrane;GO:0005902//microvillus;GO:0005737//cytoplasm;GO:0030496//midbody;GO:0032584//growth cone membrane;GO:0035748//myelin sheath abaxonal region;GO:0000145//exocyst;GO:0005829//cytosol;GO:0045202//synapse;GO:0005886//plasma membrane","GO:0047485//protein N-terminus binding;GO:0017160//Ral GTPase binding;GO:0030165//PDZ domain binding","GO:0016241//regulation of macroautophagy;GO:0006612//protein targeting to membrane;GO:0006903//vesicle targeting;GO:0006904//vesicle docking involved in exocytosis;GO:0048341//paraxial mesoderm formation;GO:0007268//chemical synaptic transmission;GO:0006893//Golgi to plasma membrane transport;GO:0006887//exocytosis","K06111//exocyst complex component 4","XP_011851219.1//PREDICTED: exocyst complex component 4 isoform X3 [Mandrillus leucophaeus];NP_068579.3//exocyst complex component 4 isoform a [Homo sapiens]","1//3;3//A2MP1"]
[2135,3174,4.05,3.65,-0.150025444004607,0.529408946692815,"*",0.371786,"EXTL2","GO:0070062//extracellular exosome;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0047237//glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity;GO:0035248//alpha-1,4-N-acetylgalactosaminyltransferase activity;GO:0016757//transferase activity, transferring glycosyl groups;GO:0005539//glycosaminoglycan binding;GO:0001888//glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity;GO:0030145//manganese ion binding","GO:0006044//N-acetylglucosamine metabolic process;GO:0036498//IRE1-mediated unfolded protein response;GO:0015012//heparan sulfate proteoglycan biosynthetic process;GO:0019276//UDP-N-acetylgalactosamine metabolic process","K02369//alpha-1,4-N-acetylglucosaminyltransferase EXTL2 [EC:2.4.1.223]","NP_001430.1//exostosin-like 2 isoform 1 [Homo sapiens];NP_001248369.1//exostosin-like 2 isoform 2 [Homo sapiens];NP_001248370.1//exostosin-like 2 isoform 3 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[56172,8231,3.46,3.12,-0.149226008774476,0.302574651904,"*",0.1775784,"ANKH","GO:0005887//integral component of plasma membrane","GO:0015114//phosphate ion transmembrane transporter activity;GO:0005315//inorganic phosphate transmembrane transporter activity;GO:0030504//inorganic diphosphate transmembrane transporter activity","GO:0030500//regulation of bone mineralization","K01368//cathepsin S [EC:3.4.22.27];K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9]","XP_011757635.1//PREDICTED: progressive ankylosis protein homolog [Macaca nemestrina]",5]
[221785,4285,4.49,4.05,-0.14879353696916,0.494925614748888,"*",0.341156,"ZSCAN25","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein;K09229//KRAB and SCAN domains-containing zinc finger protein","XP_012614902.1//zinc finger and SCAN domain-containing protein 25 isoform X1 [Microcebus murinus];XP_006942015.1//PREDICTED: zinc finger and SCAN domain-containing protein 25 isoform X1 [Felis catus];NP_001337914.1//zinc finger and SCAN domain-containing protein 25 isoform c [Homo sapiens];XP_012310967.1//zinc finger and SCAN domain-containing protein 25 isoform X1 [Aotus nancymaae]","1//3;2//1"]
[3581,2171,0.41,0.37,-0.148098638989134,0.895972586544917,"*",0.835396,"IL9R","GO:0005615//extracellular space;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004919//interleukin-9 receptor activity;GO:0004896//cytokine receptor activity;GO:0019983//interleukin-9 binding","GO:0007165//signal transduction;GO:0008283//cell proliferation;GO:1903955//positive regulation of protein targeting to mitochondrion;GO:0030307//positive regulation of cell growth","K05073//interleukin 9 receptor","NP_002177.2//interleukin-9 receptor isoform 1 precursor [Homo sapiens];NP_789743.2//interleukin-9 receptor isoform 2 [Homo sapiens]","1//3;2//1"]
[51103,1488,4.52,4.08,-0.147753620443692,0.654470665745856,"*",0.533934,"NDUFAF1","GO:0005747//mitochondrial respiratory chain complex I;GO:0005829//cytosol;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0051082//unfolded protein binding","GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0006461//protein complex assembly","K18159//NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1","NP_057097.2//complex I intermediate-associated protein 30, mitochondrial precursor [Homo sapiens]","3//A2MP1"]
[54996,2158,4.23,3.82,-0.147085025084201,0.471975395545739,"*",0.321052,"2019-03-02","GO:0070062//extracellular exosome;GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane;GO:0005777//peroxisome;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane","GO:0043546//molybdopterin cofactor binding;GO:0008940//nitrate reductase activity;GO:0030151//molybdenum ion binding;GO:0003824//catalytic activity;GO:0030170//pyridoxal phosphate binding","GO:0006805//xenobiotic metabolic process;GO:0042126//nitrate metabolic process;GO:0055114//oxidation-reduction process;GO:0051410//detoxification of nitrogen compound","K15631//molybdenum cofactor sulfurtransferase [EC:2.8.1.9]","NP_001317971.1//mitochondrial amidoxime reducing component 2 isoform b precursor [Homo sapiens];NP_060368.2//mitochondrial amidoxime reducing component 2 isoform a precursor [Homo sapiens]","4;1//3"]
[7458,2495,171.57,154.99,-0.14662217597751,{"v":2.64139604383174e-06,"d":"2.64E-06"},"*",{"v":4.67792e-07,"d":"4.68E-07"},"EIF4H","GO:0016020//membrane;GO:0005829//cytosol;GO:0005844//polysome;GO:0048471//perinuclear region of cytoplasm;GO:0016281//eukaryotic translation initiation factor 4F complex","GO:0008135//translation factor activity, RNA binding;GO:0003723//RNA binding;GO:0043024//ribosomal small subunit binding;GO:0004386//helicase activity;GO:0045296//cadherin binding;GO:0034057//RNA strand-exchange activity;GO:0003743//translation initiation factor activity;GO:0033592//RNA strand annealing activity","GO:0006413//translational initiation;GO:0019953//sexual reproduction;GO:0006446//regulation of translational initiation;GO:0097010//eukaryotic translation initiation factor 4F complex assembly;GO:0048589//developmental growth;GO:0016032//viral process;GO:0001731//formation of translation preinitiation complex","K03258//translation initiation factor 4B","XP_527788.4//PREDICTED: eukaryotic translation initiation factor 4H [Pan troglodytes];NP_071496.1//eukaryotic translation initiation factor 4H isoform 1 [Homo sapiens]","1//3"]
[80314,4093,4.57,4.13,-0.146052383638624,0.458952996755354,"*",0.309924,"EPC1","GO:0035267//NuA4 histone acetyltransferase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0032777//Piccolo NuA4 histone acetyltransferase complex","GO:0004402//histone acetyltransferase activity","GO:0045892//negative regulation of transcription, DNA-templated;GO:0040008//regulation of growth;GO:0043968//histone H2A acetylation;GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0043967//histone H4 acetylation;GO:0045814//negative regulation of gene expression, epigenetic;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0035886//vascular smooth muscle cell differentiation","K11322//enhancer of polycomb-like protein","XP_008064686.1//enhancer of polycomb homolog 1 isoform X3 [Carlito syrichta];NP_001258933.1//enhancer of polycomb homolog 1 isoform b [Homo sapiens];NP_001269320.1//enhancer of polycomb homolog 1 isoform d [Homo sapiens];XP_021798854.1//LOW QUALITY PROTEIN: enhancer of polycomb homolog 1 [Papio anubis]","1//3;3//A2MP1;2//1"]
[85315,4758,0.73,0.66,-0.145430439521564,0.765499317199282,"*",0.667308,"PAQR8","GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0003707//steroid hormone receptor activity;GO:0005496//steroid binding","GO:0048545//response to steroid hormone;GO:0048477//oogenesis;GO:0007275//multicellular organism development","K02927//large subunit ribosomal protein L40e;K15696//RING finger protein 113B;K17985//activating molecule in BECN1-regulated autophagy protein 1;K07297//adiponectin receptor","XP_003254205.2//PREDICTED: membrane progestin receptor beta [Nomascus leucogenys]",4]
[6832,2483,15.57,14.08,-0.14512161044174,0.244215993465941,"*",0.1375798,"SUPV3L1","GO:0005759//mitochondrial matrix;GO:0045025//mitochondrial degradosome;GO:0005634//nucleus;GO:0042645//mitochondrial nucleoid;GO:0005739//mitochondrion","GO:0003723//RNA binding;GO:0003677//DNA binding;GO:0005524//ATP binding;GO:0034458//3'-5' RNA helicase activity;GO:0004386//helicase activity;GO:0042803//protein homodimerization activity;GO:0003725//double-stranded RNA binding;GO:0016817//hydrolase activity, acting on acid anhydrides;GO:0004004//ATP-dependent RNA helicase activity;GO:0003678//DNA helicase activity","GO:0006401//RNA catabolic process;GO:2000827//mitochondrial RNA surveillance;GO:0035945//mitochondrial ncRNA surveillance;GO:0000962//positive regulation of mitochondrial RNA catabolic process;GO:0030307//positive regulation of cell growth;GO:0043066//negative regulation of apoptotic process;GO:0070827//chromatin maintenance;GO:0035946//mitochondrial mRNA surveillance;GO:0032508//DNA duplex unwinding;GO:0070584//mitochondrion morphogenesis;GO:0000965//mitochondrial RNA 3'-end processing;GO:0006310//DNA recombination;GO:0000958//mitochondrial mRNA catabolic process","K17675//ATP-dependent RNA helicase SUPV3L1/SUV3 [EC:3.6.4.13]","NP_001310515.1//ATP-dependent RNA helicase SUPV3L1, mitochondrial isoform 3 [Homo sapiens];NP_003162.2//ATP-dependent RNA helicase SUPV3L1, mitochondrial isoform 1 [Homo sapiens]","1//3;4"]
[3032,2196,37.65,34.05,-0.144995066659857,0.0685915391477273,"*",0.0302294,"HADHB","GO:0005740//mitochondrial envelope;GO:0070062//extracellular exosome;GO:0005783//endoplasmic reticulum;GO:0042645//mitochondrial nucleoid;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane","GO:0003723//RNA binding;GO:0003988//acetyl-CoA C-acyltransferase activity;GO:0016509//long-chain-3-hydroxyacyl-CoA dehydrogenase activity;GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups;GO:0003857//3-hydroxyacyl-CoA dehydrogenase activity;GO:0004300//enoyl-CoA hydratase activity","GO:0006635//fatty acid beta-oxidation;GO:0008152//metabolic process;GO:0035965//cardiolipin acyl-chain remodeling","K07509//acetyl-CoA acyltransferase [EC:2.3.1.16]","NP_001268442.1//trifunctional enzyme subunit beta, mitochondrial isoform 3 [Homo sapiens];NP_001268441.1//trifunctional enzyme subunit beta, mitochondrial isoform 2 precursor [Homo sapiens];NP_000174.1//trifunctional enzyme subunit beta, mitochondrial isoform 1 precursor [Homo sapiens]","1//3;2//1"]
[8857,16407,0.42,0.38,-0.144389909335175,0.712159577723104,"*",0.597984,"FCGBP","GO:0070062//extracellular exosome","NA","NA","K18273//alpha-tectorin","NP_003881.2//IgGFc-binding protein precursor [Homo sapiens]","2//1"]
[55005,2013,4.95,4.48,-0.143929792909368,0.319980987505241,"*",0.1910992,"RMND1","GO:0005739//mitochondrion","NA","GO:0006412//translation;GO:0070131//positive regulation of mitochondrial translation","K21456//glutathione synthase [EC:6.3.2.3]","NP_060379.2//required for meiotic nuclear division protein 1 homolog isoform 1 [Homo sapiens];XP_003811549.1//PREDICTED: required for meiotic nuclear division protein 1 homolog isoform X1 [Pan paniscus]","1//3;3//A2MP1"]
[8417,3966,5.19,4.7,-0.143073781792881,0.0891609600762008,"*",0.0410194,"STX7","GO:0005770//late endosome;GO:0031982//vesicle;GO:0070820//tertiary granule;GO:0012505//endomembrane system;GO:0016021//integral component of membrane;GO:0055037//recycling endosome;GO:0005886//plasma membrane;GO:0005769//early endosome;GO:0042582//azurophil granule;GO:0070062//extracellular exosome;GO:0005765//lysosomal membrane;GO:0005764//lysosome;GO:0001772//immunological synapse;GO:0048471//perinuclear region of cytoplasm;GO:0005768//endosome;GO:0031901//early endosome membrane;GO:0030139//endocytic vesicle;GO:0031201//SNARE complex","GO:0000149//SNARE binding;GO:0005484//SNAP receptor activity;GO:0019869//chloride channel inhibitor activity;GO:0019905//syntaxin binding","GO:0051640//organelle localization;GO:0070925//organelle assembly;GO:0016192//vesicle-mediated transport;GO:1903076//regulation of protein localization to plasma membrane;GO:0006886//intracellular protein transport;GO:0006906//vesicle fusion;GO:1902685//positive regulation of receptor localization to synapse;GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0048278//vesicle docking","K08488//syntaxin 7","NP_001313509.1//syntaxin-7 isoform b [Homo sapiens];NP_003560.2//syntaxin-7 isoform a [Homo sapiens]","1//3;2//1"]
[65985,3309,10.55,9.56,-0.142160475613799,0.181998034021233,"*",0.0955108,"AACS","GO:0005829//cytosol","GO:0030729//acetoacetate-CoA ligase activity;GO:0047760//butyrate-CoA ligase activity;GO:0005524//ATP binding","GO:0032024//positive regulation of insulin secretion;GO:0050872//white fat cell differentiation;GO:0045471//response to ethanol;GO:0006631//fatty acid metabolic process;GO:0007584//response to nutrient;GO:0034201//response to oleic acid;GO:0046951//ketone body biosynthetic process;GO:0042493//response to drug;GO:0071394//cellular response to testosterone stimulus;GO:0001889//liver development;GO:0060612//adipose tissue development;GO:0014074//response to purine-containing compound;GO:0071333//cellular response to glucose stimulus;GO:0071397//cellular response to cholesterol;GO:0042594//response to starvation;GO:0006629//lipid metabolic process","K01907//acetoacetyl-CoA synthetase [EC:6.2.1.16]","NP_076417.2//acetoacetyl-CoA synthetase isoform 1 [Homo sapiens];NP_001306769.1//acetoacetyl-CoA synthetase isoform 3 [Homo sapiens];NP_001306768.1//acetoacetyl-CoA synthetase isoform 2 [Homo sapiens]","4;1//3"]
[9370,4629,0.96,0.87,-0.142019004872428,0.736096304720407,"*",0.634534,"ADIPOQ","NA","NA","NA","K06237//collagen, type IV, alpha","XP_006123490.1//PREDICTED: otolin-1 isoform X2 [Pelodiscus sinensis];XP_006123489.1//PREDICTED: otolin-1 isoform X1 [Pelodiscus sinensis]","1//3;3//A2MP1"]
[132884,4426,1.07,0.97,-0.141554144214019,0.699268115606936,"*",0.583132,"EVC2","GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0060170//ciliary membrane;GO:0005634//nucleus;GO:0016021//integral component of membrane;GO:0098797//plasma membrane protein complex;GO:0005737//cytoplasm","NA","GO:0007224//smoothened signaling pathway","K19608//ellis van creveld syndrome protein 2","NP_001159608.1//limbin isoform 2 [Homo sapiens];XP_001155684.1//PREDICTED: limbin isoform X1 [Pan troglodytes]","1//3;4"]
[5660,2908,249.39,226.18,-0.140932252929329,{"v":2.72181375609756e-09,"d":"2.72E-09"},"*",{"v":3.21356e-10,"d":"3.21E-10"},"PSAP","GO:0005765//lysosomal membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005764//lysosome;GO:0035577//azurophil granule membrane;GO:0005576//extracellular region;GO:0016021//integral component of membrane;GO:0043202//lysosomal lumen;GO:0005739//mitochondrion;GO:0005886//plasma membrane","GO:1905573//ganglioside GM1 binding;GO:0042802//identical protein binding;GO:1905574//ganglioside GM2 binding;GO:0042803//protein homodimerization activity;GO:0005543//phospholipid binding;GO:0008289//lipid binding;GO:1905577//ganglioside GP1c binding;GO:1905576//ganglioside GT1b binding;GO:0004565//beta-galactosidase activity;GO:0001664//G-protein coupled receptor binding;GO:1905575//ganglioside GM3 binding;GO:0008047//enzyme activator activity","GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0006869//lipid transport;GO:0006687//glycosphingolipid metabolic process;GO:0071310//cellular response to organic substance;GO:0060742//epithelial cell differentiation involved in prostate gland development;GO:1903206//negative regulation of hydrogen peroxide-induced cell death;GO:0002576//platelet degranulation;GO:0006665//sphingolipid metabolic process;GO:1905572//ganglioside GM1 transport to membrane;GO:0019216//regulation of lipid metabolic process;GO:0043410//positive regulation of MAPK cascade;GO:0043312//neutrophil degranulation;GO:0010506//regulation of autophagy;GO:0060736//prostate gland growth","K12382//saposin","BAD93013.1//prosaposin variant, partial [Homo sapiens]","3//A2MP1;2//1"]
[5598,2859,18.39,16.68,-0.140802190967274,0.168178342400388,"*",0.0869318,"MAPK7","GO:0016605//PML body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0004674//protein serine/threonine kinase activity;GO:0051019//mitogen-activated protein kinase binding;GO:0005524//ATP binding;GO:0004707//MAP kinase activity","GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0051534//negative regulation of NFAT protein import into nucleus;GO:0043407//negative regulation of MAP kinase activity;GO:0050728//negative regulation of inflammatory response;GO:0071499//cellular response to laminar fluid shear stress;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0030821//negative regulation of cAMP catabolic process;GO:0070377//negative regulation of ERK5 cascade;GO:0071363//cellular response to growth factor stimulus;GO:0007411//axon guidance;GO:0070301//cellular response to hydrogen peroxide;GO:1902176//negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:0060761//negative regulation of response to cytokine stimulus;GO:0007165//signal transduction;GO:0051247//positive regulation of protein metabolic process;GO:0043066//negative regulation of apoptotic process;GO:0036003//positive regulation of transcription from RNA polymerase II promoter in response to stress;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:0019933//cAMP-mediated signaling;GO:0034115//negative regulation of heterotypic cell-cell adhesion;GO:0045765//regulation of angiogenesis;GO:0018105//peptidyl-serine phosphorylation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0051344//negative regulation of cyclic-nucleotide phosphodiesterase activity;GO:0007049//cell cycle","K04464//mitogen-activated protein kinase 7 [EC:2.7.11.24]","XP_008957611.1//PREDICTED: mitogen-activated protein kinase 7 isoform X3 [Pan paniscus];NP_002740.2//mitogen-activated protein kinase 7 isoform 1 [Homo sapiens]","3//A2MP1;2//1"]
[4670,2508,71.23,64.64,-0.140057792197896,0.00362375404112597,"*",0.001136308,"HNRNPM","GO:0016020//membrane;GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0005654//nucleoplasm;GO:0016363//nuclear matrix;GO:0042382//paraspeckles;GO:0071013//catalytic step 2 spliceosome;GO:0005681//spliceosomal complex;GO:0005887//integral component of plasma membrane;GO:0005730//nucleolus;GO:0019013//viral nucleocapsid","GO:0003723//RNA binding;GO:0019904//protein domain specific binding","GO:0016070//RNA metabolic process;GO:0000398//mRNA splicing, via spliceosome;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0000380//alternative mRNA splicing, via spliceosome","K12887//heterogeneous nuclear ribonucleoprotein M","XP_002761735.2//PREDICTED: heterogeneous nuclear ribonucleoprotein M isoform X5 [Callithrix jacchus];XP_008985392.1//PREDICTED: heterogeneous nuclear ribonucleoprotein M isoform X1 [Callithrix jacchus];BAD92970.1//heterogeneous nuclear ribonucleoprotein M isoform a variant, partial [Homo sapiens]","1//3;4;3//A2MP1"]
[26135,6725,34.97,31.74,-0.139815667862534,0.00117609367710631,"*",0.000333818,"SERBP1","NA","NA","NA","K13199//plasminogen activator inhibitor 1 RNA-binding protein","EAX06490.1//SERPINE1 mRNA binding protein 1, isoform CRA_b [Homo sapiens];EAX06492.1//SERPINE1 mRNA binding protein 1, isoform CRA_d [Homo sapiens];EAX06495.1//SERPINE1 mRNA binding protein 1, isoform CRA_f [Homo sapiens];EAX06491.1//SERPINE1 mRNA binding protein 1, isoform CRA_c [Homo sapiens]","1//3;3//A2MP1"]
[5757,1220,1343.03,1219.46,-0.139249094910679,{"v":5.18764869501823e-19,"d":"5.19E-19"},"*",{"v":2.67274E-20,"d":"2.67E-20"},"PTMA","GO:0016021//integral component of membrane","NA","GO:0007275//multicellular organism development","K19607//X-linked retinitis pigmentosa GTPase regulator","XP_020930232.1//prothymosin alpha isoform X1 [Sus scrofa];ELW63422.1//hypothetical protein TREES_T100016057 [Tupaia chinensis]","4;1//3"]
[51501,1187,17.86,16.22,-0.13895826090395,0.415027874247492,"*",0.271896,"HIKESHI","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005622//intracellular","GO:0008565//protein transporter activity;GO:0030544//Hsp70 protein binding","GO:0030324//lung development;GO:1900034//regulation of cellular response to heat;GO:0006606//protein import into nucleus;GO:0007030//Golgi organization;GO:0015031//protein transport;GO:0034605//cellular response to heat","NA","ELW68942.1//hypothetical protein TREES_T100012980 [Tupaia chinensis];EPQ13581.1//Hypothetical protein D623_10014362 [Myotis brandtii];NP_057485.2//protein Hikeshi isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[140894,2560,3.28,2.98,-0.138383484155922,0.648129819712729,"*",0.491514,"CNBD2","GO:0005829//cytosol","GO:0030552//cAMP binding","GO:0007283//spermatogenesis","K12581//CCR4-NOT transcription complex subunit 7/8;K07376//cGMP-dependent protein kinase 1 [EC:2.7.11.12];K04351//Rap guanine nucleotide exchange factor 4;K17532//STE20-related kinase adapter protein beta;K01064//wingless-type MMTV integration site family, member 9;K19477//cGMP-dependent protein kinase 2 [EC:2.7.11.12]","NP_001291296.1//cyclic nucleotide-binding domain-containing protein 2 isoform 3 [Homo sapiens];NP_543024.2//cyclic nucleotide-binding domain-containing protein 2 isoform 1 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[961,5309,6.37,5.79,-0.137730024267064,0.292634076736447,"*",0.1706452,"CD47","GO:0070062//extracellular exosome;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane;GO:0070821//tertiary granule membrane;GO:0005886//plasma membrane","GO:0070053//thrombospondin receptor activity","GO:0050900//leukocyte migration;GO:0050729//positive regulation of inflammatory response;GO:0022409//positive regulation of cell-cell adhesion;GO:0050870//positive regulation of T cell activation;GO:0050766//positive regulation of phagocytosis;GO:0007155//cell adhesion;GO:0030198//extracellular matrix organization;GO:0007229//integrin-mediated signaling pathway;GO:0043312//neutrophil degranulation;GO:0009617//response to bacterium;GO:0008228//opsonization;GO:0008284//positive regulation of cell proliferation","K06266//CD47 antigen (Rh-related antigen, integrin-associated signal transducer)","NP_001768.1//leukocyte surface antigen CD47 isoform 1 precursor [Homo sapiens];NP_942088.1//leukocyte surface antigen CD47 isoform 2 precursor [Homo sapiens]","3//A2MP1;2//1"]
[6462,1232,0.55,0.5,-0.137503523749935,0.723389255717256,"*",0.609904,"SHBG","GO:0070062//extracellular exosome;GO:0005576//extracellular region","GO:0005497//androgen binding;GO:0005496//steroid binding","NA","K03908//protein S;K05464//growth arrest-specific 6","NP_001276045.1//sex hormone-binding globulin isoform 7 [Homo sapiens];NP_001031.2//sex hormone-binding globulin isoform 1 precursor [Homo sapiens];XP_011907937.1//PREDICTED: sex hormone-binding globulin isoform X5 [Cercocebus atys];XP_011907928.1//PREDICTED: sex hormone-binding globulin isoform X4 [Cercocebus atys];XP_017705956.1//PREDICTED: sex hormone-binding globulin isoform X2 [Rhinopithecus bieti];NP_001270513.1//sex hormone-binding globulin [Macaca fascicularis];CAA34400.1//SHBG related protein (288 AA), partial [Homo sapiens]","1//3;4;2//1"]
[7070,2096,5.17,4.7,-0.137503523749935,0.58522976852168,"*",0.429232,"THY1","GO:0070062//extracellular exosome;GO:0030425//dendrite;GO:0005783//endoplasmic reticulum;GO:0031362//anchored component of external side of plasma membrane;GO:0005925//focal adhesion;GO:0009897//external side of plasma membrane;GO:0016324//apical plasma membrane;GO:0043209//myelin sheath;GO:0030673//axolemma;GO:0030426//growth cone;GO:0009986//cell surface;GO:0045121//membrane raft;GO:0005887//integral component of plasma membrane;GO:0032590//dendrite membrane;GO:0005829//cytosol;GO:0005576//extracellular region;GO:0032809//neuronal cell body membrane;GO:0005886//plasma membrane","GO:0005178//integrin binding;GO:0019901//protein kinase binding;GO:0005096//GTPase activator activity;GO:0034235//GPI anchor binding","GO:0001952//regulation of cell-matrix adhesion;GO:0006501//C-terminal protein lipidation;GO:2000298//regulation of Rho-dependent protein serine/threonine kinase activity;GO:0043547//positive regulation of GTPase activity;GO:0050860//negative regulation of T cell receptor signaling pathway;GO:0098609//cell-cell adhesion;GO:0030334//regulation of cell migration;GO:0002693//positive regulation of cellular extravasation;GO:0007229//integrin-mediated signaling pathway;GO:0048041//focal adhesion assembly;GO:0034116//positive regulation of heterotypic cell-cell adhesion;GO:0043113//receptor clustering;GO:0070571//negative regulation of neuron projection regeneration;GO:0001525//angiogenesis;GO:0050852//T cell receptor signaling pathway;GO:0051894//positive regulation of focal adhesion assembly;GO:0007267//cell-cell signaling;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0030336//negative regulation of cell migration;GO:0050870//positive regulation of T cell activation;GO:0046777//protein autophosphorylation;GO:0061099//negative regulation of protein tyrosine kinase activity;GO:0007155//cell adhesion;GO:0006469//negative regulation of protein kinase activity;GO:0050771//negative regulation of axonogenesis;GO:0007010//cytoskeleton organization;GO:0046549//retinal cone cell development","K06514//Thy-1 cell surface antigen","NP_006279.2//thy-1 membrane glycoprotein preproprotein [Homo sapiens]","4;1//3"]
[883,2280,11.09,10.09,-0.136333191055353,0.406471607049986,"*",0.264204,"KYAT1","GO:0005654//nucleoplasm;GO:0005829//cytosol","GO:0047312//L-phenylalanine:pyruvate aminotransferase activity;GO:0047945//L-glutamine:pyruvate aminotransferase activity;GO:0070548//L-glutamine aminotransferase activity;GO:0008483//transaminase activity;GO:0016212//kynurenine-oxoglutarate transaminase activity;GO:0030170//pyridoxal phosphate binding;GO:0042803//protein homodimerization activity;GO:0047316//glutamine-phenylpyruvate transaminase activity;GO:0047804//cysteine-S-conjugate beta-lyase activity","GO:0008652//cellular amino acid biosynthetic process;GO:0009058//biosynthetic process;GO:0006575//cellular modified amino acid metabolic process;GO:0006569//tryptophan catabolic process;GO:0070189//kynurenine metabolic process;GO:0097053//L-kynurenine catabolic process;GO:0006559//L-phenylalanine catabolic process","K00816//kynurenine---oxoglutarate transaminase / cysteine-S-conjugate beta-lyase / glutamine---phenylpyruvate transaminase [EC:2.6.1.7 4.4.1.13 2.6.1.64]","XP_011786635.1//PREDICTED: kynurenine--oxoglutarate transaminase 1 isoform X1 [Colobus angolensis palliatus];XP_011786637.1//PREDICTED: kynurenine--oxoglutarate transaminase 1 isoform X3 [Colobus angolensis palliatus];NP_001339924.1//kynurenine--oxoglutarate transaminase 1 isoform d [Homo sapiens];NP_001339927.1//kynurenine--oxoglutarate transaminase 1 isoform e [Homo sapiens];NP_001274319.1//kynurenine--oxoglutarate transaminase 1 isoform c [Homo sapiens];XP_011786636.1//PREDICTED: kynurenine--oxoglutarate transaminase 1 isoform X2 [Colobus angolensis palliatus];XP_011894302.1//PREDICTED: kynurenine--oxoglutarate transaminase 1 isoform X1 [Cercocebus atys]","4;1//3;2//1"]
[3916,2560,64.56,58.75,-0.136051726938056,0.0107979651418312,"*",3.76516E-3,"LAMP1","GO:0016020//membrane;GO:0010008//endosome membrane;GO:0030425//dendrite;GO:0005770//late endosome;GO:0009897//external side of plasma membrane;GO:0044194//cytolytic granule;GO:0042470//melanosome;GO:0005737//cytoplasm;GO:0043025//neuronal cell body;GO:0035577//azurophil granule membrane;GO:0044754//autolysosome;GO:0005887//integral component of plasma membrane;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0070062//extracellular exosome;GO:0005765//lysosomal membrane;GO:0008021//synaptic vesicle;GO:0101003//ficolin-1-rich granule membrane;GO:0061474//phagolysosome membrane;GO:0005764//lysosome;GO:0048471//perinuclear region of cytoplasm;GO:0097208//alveolar lamellar body;GO:0042383//sarcolemma;GO:0005771//multivesicular body","GO:0019904//protein domain specific binding;GO:0001618//virus receptor activity;GO:0019899//enzyme binding","GO:0090160//Golgi to lysosome transport;GO:0072594//establishment of protein localization to organelle;GO:0008626//granzyme-mediated apoptotic signaling pathway;GO:0043323//positive regulation of natural killer cell degranulation;GO:0043312//neutrophil degranulation;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0048102//autophagic cell death;GO:0050821//protein stabilization;GO:1902513//regulation of organelle transport along microtubule","K06528//lysosomal-associated membrane protein 1/2","NP_005552.3//lysosome-associated membrane glycoprotein 1 precursor [Homo sapiens]","3//A2MP1"]
[9683,7121,5.91,5.38,-0.135551957620908,0.249662673574671,"*",0.1411796,"N4BP1","GO:0016605//PML body;GO:0005730//nucleolus","NA","GO:0031397//negative regulation of protein ubiquitination;GO:0034644//cellular response to UV;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process","K18668//ribonuclease ZC3H12 [EC:3.1.-.-]","NP_694574.3//NEDD4-binding protein 1 [Homo sapiens]","3//A2MP1"]
[6645,9771,4.7,4.28,-0.135049960163853,0.219732589983919,"*",0.1197566,"SNTB2","GO:0030658//transport vesicle membrane;GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005874//microtubule;GO:0005925//focal adhesion;GO:0005737//cytoplasm;GO:0043234//protein complex;GO:0016010//dystrophin-associated glycoprotein complex;GO:0045202//synapse","GO:0003779//actin binding;GO:0003723//RNA binding;GO:0005198//structural molecule activity;GO:0005516//calmodulin binding","NA","K01368//cathepsin S [EC:3.4.22.27];K14548//U3 small nucleolar RNA-associated protein 4;K12196//vacuolar protein-sorting-associated protein 4","XP_001147485.4//PREDICTED: beta-2-syntrophin [Pan troglodytes]","3//A2MP1"]
[79411,2403,5.39,4.91,-0.134562248437812,0.332713273124545,"*",0.200182,"GLB1L","GO:0005615//extracellular space;GO:0005773//vacuole","GO:0004565//beta-galactosidase activity","GO:0005975//carbohydrate metabolic process","K12309//beta-galactosidase [EC:3.2.1.23]","NP_078782.3//beta-galactosidase-1-like protein isoform 1 precursor [Homo sapiens];NP_001273356.1//beta-galactosidase-1-like protein isoform 2 precursor [Homo sapiens]","1//3;4"]
[9394,3966,11.72,10.68,-0.134060922734694,0.230275081573034,"*",0.128299,"HS6ST1","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0008146//sulfotransferase activity;GO:0017095//heparan sulfate 6-O-sulfotransferase activity","GO:0060716//labyrinthine layer blood vessel development;GO:0001525//angiogenesis;GO:0048286//lung alveolus development;GO:0006024//glycosaminoglycan biosynthetic process;GO:0048666//neuron development;GO:0015015//heparan sulfate proteoglycan biosynthetic process, enzymatic modification","K02514//heparan sulfate 6-O-sulfotransferase HS6ST1 [EC:2.8.2.-]","NP_004798.3//heparan-sulfate 6-O-sulfotransferase 1 [Homo sapiens]","2//1"]
[80724,4055,3.84,3.5,-0.133751388888827,0.490985420669578,"*",0.337856,"ACAD10","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors;GO:0016787//hydrolase activity;GO:0050660//flavin adenine dinucleotide binding;GO:0003995//acyl-CoA dehydrogenase activity","GO:0033539//fatty acid beta-oxidation using acyl-CoA dehydrogenase;GO:0006635//fatty acid beta-oxidation","K11729//acyl-CoA dehydrogenase family member 10","NP_079523.3//acyl-CoA dehydrogenase family member 10 isoform b [Homo sapiens];NP_001130010.1//acyl-CoA dehydrogenase family member 10 isoform a [Homo sapiens]","1//3;5"]
[140701,1776,3.63,3.31,-0.133138331188533,0.697259340144231,"*",0.581064,"ABHD16B","NA","GO:0016787//hydrolase activity","NA","K08869//aarF domain-containing kinase;K13172//serine/arginine repetitive matrix protein 2;K19720//collagen, type III, alpha","EAW75202.1//hCG1647005 [Homo sapiens]","3//A2MP1"]
[80110,4676,0.91,0.83,-0.132755208851772,0.73405269282854,"*",0.631164,"ZNF614","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","ELW48892.1//Zinc finger protein 614 [Tupaia chinensis]","3//A2MP1"]
[93,11373,0.57,0.52,-0.132450296023649,0.701142919194189,"*",0.5861,"ACVR2B","NA","NA","NA","K13596//activin receptor type-2B [EC:2.7.11.30]","XP_003894716.3//activin receptor type-2B isoform X1 [Papio anubis]","3//A2MP1"]
[1525,5079,3.78,3.45,-0.131789872555541,0.653599763097199,"*",0.496726,"CXADR","GO:0016323//basolateral plasma membrane;GO:0005615//extracellular space;GO:0031594//neuromuscular junction;GO:0030054//cell junction;GO:0005737//cytoplasm;GO:0030426//growth cone;GO:0005887//integral component of plasma membrane;GO:0005913//cell-cell adherens junction;GO:0005911//cell-cell junction;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005923//bicellular tight junction;GO:0014704//intercalated disc;GO:0005886//plasma membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016327//apicolateral plasma membrane;GO:0001669//acrosomal vesicle;GO:0005912//adherens junction;GO:0043005//neuron projection;GO:0030175//filopodium;GO:0044297//cell body;GO:0045121//membrane raft;GO:0043234//protein complex","GO:0050839//cell adhesion molecule binding;GO:0042802//identical protein binding;GO:0005102//receptor binding;GO:0086082//cell adhesive protein binding involved in AV node cell-bundle of His cell communication;GO:0071253//connexin binding;GO:0005178//integrin binding;GO:0030165//PDZ domain binding;GO:0001618//virus receptor activity;GO:0008013//beta-catenin binding","GO:0048739//cardiac muscle fiber development;GO:0098904//regulation of AV node cell action potential;GO:0008354//germ cell migration;GO:0045216//cell-cell junction organization;GO:0034109//homotypic cell-cell adhesion;GO:0050776//regulation of immune response;GO:0046629//gamma-delta T cell activation;GO:0031532//actin cytoskeleton reorganization;GO:0086072//AV node cell-bundle of His cell adhesion involved in cell communication;GO:0030593//neutrophil chemotaxis;GO:0007507//heart development;GO:0050900//leukocyte migration;GO:0051607//defense response to virus;GO:0070633//transepithelial transport;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007005//mitochondrion organization;GO:0086067//AV node cell to bundle of His cell communication;GO:0010669//epithelial structure maintenance","K06788//coxsackievirus and adenovirus receptor","NP_001193995.1//coxsackievirus and adenovirus receptor isoform 5 precursor [Homo sapiens];NP_001329.1//coxsackievirus and adenovirus receptor isoform 1 precursor [Homo sapiens];NP_001193993.1//coxsackievirus and adenovirus receptor isoform 3 precursor [Homo sapiens];NP_001193992.1//coxsackievirus and adenovirus receptor isoform 2 precursor [Homo sapiens];NP_001193994.1//coxsackievirus and adenovirus receptor isoform 4 precursor [Homo sapiens]","4;1//3"]
[114788,12643,0.23,0.21,-0.131244533278253,0.813164917520742,"*",0.730138,"CSMD3","NA","NA","NA","K17495//CUB and sushi domain-containing protein","XP_004011825.1//PREDICTED: CUB and sushi domain-containing protein 3 isoform X1 [Ovis aries];XP_004679689.1//PREDICTED: CUB and sushi domain-containing protein 3 [Condylura cristata];XP_003408490.1//PREDICTED: CUB and sushi domain-containing protein 3 isoform X2 [Loxodonta africana]","1//3;2//1"]
[27316,2090,113.34,103.53,-0.130608227952854,3.07493353665452E-3,"*",0.000950546,"RBMX","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005615//extracellular space;GO:0071013//catalytic step 2 spliceosome;GO:0030529//intracellular ribonucleoprotein complex;GO:0044530//supraspliceosomal complex;GO:0005719//nuclear euchromatin","GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0003682//chromatin binding;GO:0003727//single-stranded RNA binding;GO:0001047//core promoter binding","GO:0006397//mRNA processing;GO:0016070//RNA metabolic process;GO:0006509//membrane protein ectodomain proteolysis;GO:0001649//osteoblast differentiation;GO:0006376//mRNA splice site selection;GO:0000398//mRNA splicing, via spliceosome;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0051260//protein homooligomerization;GO:0006366//transcription from RNA polymerase II promoter;GO:0048026//positive regulation of mRNA splicing, via spliceosome;GO:0071347//cellular response to interleukin-1;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0008380//RNA splicing;GO:0048025//negative regulation of mRNA splicing, via spliceosome;GO:0051259//protein oligomerization","K12885//heterogeneous nuclear ribonucleoprotein G","KFO37284.1//Heterogeneous nuclear ribonucleoprotein G [Fukomys damarensis];NP_001158275.1//RNA-binding motif protein, X chromosome isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[8467,7926,18.48,16.89,-0.129795428614672,0.0226951417859488,"*",0.00865524,"SMARCA5","NA","NA","NA","K11654//SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:3.6.4.-]","XP_012309409.1//SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 isoform X1 [Aotus nancymaae]","3//A2MP1"]
[26022,1732,16.71,15.28,-0.129067190025439,0.382233514174096,"*",0.238878,"TMEM98","GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane","NA","NA","K21626//cyclin-D1-binding protein 1","NP_056359.2//transmembrane protein 98 [Homo sapiens]","1//3;2//1"]
[1616,2591,26.57,24.3,-0.128841913997363,0.063718333037122,"*",0.0278304,"DAXX","GO:0016605//PML body;GO:0070603//SWI/SNF superfamily-type complex;GO:0000775//chromosome, centromeric region","GO:0042393//histone binding;GO:0003714//transcription corepressor activity;GO:0047485//protein N-terminus binding;GO:0002039//p53 binding;GO:0031625//ubiquitin protein ligase binding;GO:0030295//protein kinase activator activity;GO:0046982//protein heterodimerization activity;GO:0019901//protein kinase binding;GO:0050681//androgen receptor binding;GO:0003713//transcription coactivator activity;GO:0032183//SUMO binding","GO:0031396//regulation of protein ubiquitination;GO:0045892//negative regulation of transcription, DNA-templated;GO:1903936//cellular response to sodium arsenite;GO:0006338//chromatin remodeling;GO:0006334//nucleosome assembly;GO:0034620//cellular response to unfolded protein;GO:1901216//positive regulation of neuron death;GO:0071280//cellular response to copper ion;GO:0034605//cellular response to heat;GO:0030521//androgen receptor signaling pathway;GO:0072738//cellular response to diamide;GO:0071276//cellular response to cadmium ion","K02308//death-associated protein 6","XP_007971134.1//PREDICTED: death domain-associated protein 6 isoform X3 [Chlorocebus sabaeus]","4;1//3"]
[9196,2458,1.53,1.4,-0.128104825747685,0.779056914759725,"*",0.682004,"KCNAB3","GO:0016021//integral component of membrane;GO:0005737//cytoplasm","GO:0005249//voltage-gated potassium channel activity","NA","K04884//potassium voltage-gated channel Shaker-related subfamily A, beta member 3","XP_004684688.1//PREDICTED: voltage-gated potassium channel subunit beta-3 isoform X1 [Condylura cristata]","3//A2MP1"]
[79913,2479,6.24,5.71,-0.128055283499406,0.573588799448656,"*",0.416816,"ACTR5","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031011//Ino80 complex;GO:0005737//cytoplasm","NA","GO:0006302//double-strand break repair;GO:0006355//regulation of transcription, DNA-templated;GO:0016579//protein deubiquitination;GO:0006351//transcription, DNA-templated;GO:0006310//DNA recombination;GO:0070914//UV-damage excision repair","K11672//actin-related protein 5","XP_003253623.2//PREDICTED: actin-related protein 5 [Nomascus leucogenys]","3//A2MP1"]
[51115,2219,9.95,9.11,-0.12724547162896,0.0833148623412479,"*",0.0377822,"RMDN1","GO:0000922//spindle pole;GO:0005874//microtubule;GO:0005813//centrosome;GO:0005739//mitochondrion","NA","NA","K15376//gephyrin [EC:2.10.1.1 2.7.7.75];K15696//RING finger protein 113B;K17985//activating molecule in BECN1-regulated autophagy protein 1;K01064//wingless-type MMTV integration site family, member 9","NP_001273648.1//regulator of microtubule dynamics protein 1 isoform 3 [Homo sapiens];NP_001273636.1//regulator of microtubule dynamics protein 1 isoform 2 [Homo sapiens];NP_057117.2//regulator of microtubule dynamics protein 1 isoform 1 [Homo sapiens];XP_016869008.1//PREDICTED: regulator of microtubule dynamics protein 1 isoform X12 [Homo sapiens]","1//3;2//1"]
[51704,2941,12.62,11.56,-0.12657051248187,0.335510433499584,"*",0.202138,"GPRC5B","GO:0016021//integral component of membrane","GO:0004930//G-protein coupled receptor activity","NA","K04619//G protein-coupled receptor family C group 5 member B","NP_001291700.1//G-protein coupled receptor family C group 5 member B isoform 2 [Homo sapiens];NP_001306363.1//G-protein coupled receptor family C group 5 member B [Macaca fascicularis]","1//3;2//1"]
[4668,3726,4.77,4.37,-0.126355986504913,0.527351415678231,"*",0.370176,"NAGA","GO:0070062//extracellular exosome;GO:0005764//lysosome;GO:0005737//cytoplasm","GO:0008456//alpha-N-acetylgalactosaminidase activity;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0042803//protein homodimerization activity;GO:0004557//alpha-galactosidase activity","GO:0046477//glycosylceramide catabolic process;GO:0016139//glycoside catabolic process;GO:0009311//oligosaccharide metabolic process;GO:0005975//carbohydrate metabolic process;GO:0019377//glycolipid catabolic process;GO:0016052//carbohydrate catabolic process","K01204//alpha-N-acetylgalactosaminidase [EC:3.2.1.49]","NP_000253.1//alpha-N-acetylgalactosaminidase precursor [Homo sapiens]","2//1"]
[129831,1831,3.12,2.86,-0.125530882083859,0.729304210962963,"*",0.616352,"RBM45","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0003723//RNA binding","GO:0007399//nervous system development;GO:0030154//cell differentiation","K13207//CUG-BP- and ETR3-like factor","NP_694453.2//RNA-binding protein 45 [Homo sapiens]","3//A2MP1"]
[5824,3667,17.92,16.43,-0.12523815710753,0.19029626572171,"*",0.1008544,"PEX19","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031526//brush border membrane;GO:0005777//peroxisome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043234//protein complex;GO:0016021//integral component of membrane;GO:0005778//peroxisomal membrane","GO:0047485//protein N-terminus binding;GO:0051117//ATPase binding;GO:0033328//peroxisome membrane targeting sequence binding;GO:0036105//peroxisome membrane class-1 targeting sequence binding","GO:0007031//peroxisome organization;GO:0055085//transmembrane transport;GO:0016557//peroxisome membrane biogenesis;GO:1900131//negative regulation of lipid binding;GO:0061077//chaperone-mediated protein folding;GO:0072663//establishment of protein localization to peroxisome;GO:0045046//protein import into peroxisome membrane;GO:0006625//protein targeting to peroxisome;GO:0072321//chaperone-mediated protein transport;GO:0050821//protein stabilization;GO:0016559//peroxisome fission","K13337//peroxin-19","XP_007974687.1//PREDICTED: peroxisomal biogenesis factor 19 isoform X1 [Chlorocebus sabaeus]","1//3;3//A2MP1"]
[26520,1101,29.23,26.8,-0.125216828460918,0.947344727583487,"*",0.902154,"TIMM9","GO:0005758//mitochondrial intermembrane space;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0042721//mitochondrial inner membrane protein insertion complex;GO:0042719//mitochondrial intermembrane space protein transporter complex","GO:0046872//metal ion binding;GO:0008565//protein transporter activity;GO:0008270//zinc ion binding;GO:0051087//chaperone binding;GO:0042803//protein homodimerization activity;GO:0005215//transporter activity","GO:0006626//protein targeting to mitochondrion;GO:0007605//sensory perception of sound;GO:0015031//protein transport;GO:0072321//chaperone-mediated protein transport;GO:0045039//protein import into mitochondrial inner membrane","K17777//mitochondrial import inner membrane translocase subunit TIM9","NP_001291417.1//mitochondrial import inner membrane translocase subunit Tim9 isoform b [Homo sapiens];NP_001291418.1//mitochondrial import inner membrane translocase subunit Tim9 isoform c [Homo sapiens];NP_001291419.1//mitochondrial import inner membrane translocase subunit Tim9 isoform d [Homo sapiens];EDL36554.1//translocase of inner mitochondrial membrane 9 homolog (yeast), isoform CRA_a, partial [Mus musculus]","1//3;3//A2MP1"]
[8824,3945,17.7,16.24,-0.124197727785184,0.175750103774946,"*",0.0915168,"CES2","GO:0005788//endoplasmic reticulum lumen;GO:0005783//endoplasmic reticulum","GO:0016787//hydrolase activity;GO:0047374//methylumbelliferyl-acetate deacetylase activity;GO:0052689//carboxylic ester hydrolase activity","GO:0006693//prostaglandin metabolic process;GO:0006805//xenobiotic metabolic process;GO:0009056//catabolic process","K03927//carboxylesterase 2 [EC:3.1.1.1 3.1.1.84 3.1.1.56]","NP_932327.1//cocaine esterase isoform 2 [Homo sapiens];NP_003860.2//cocaine esterase isoform 1 [Homo sapiens]","2//1;5"]
[84461,5217,12.55,11.52,-0.123546647395822,0.189629019768267,"*",0.1004058,"NEURL4","GO:0005814//centriole","NA","NA","K16777//neuralized-like protein 4","NP_001005408.1//neuralized-like protein 4 isoform 2 [Homo sapiens];NP_115818.2//neuralized-like protein 4 isoform 1 [Homo sapiens]","1//3;2//1"]
[84910,5224,3.78,3.47,-0.123450571642812,0.502145354733995,"*",0.348616,"TMEM87B","GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","NA","GO:0042147//retrograde transport, endosome to Golgi","NA","NP_116213.1//transmembrane protein 87B isoform 1 precursor [Homo sapiens];NP_001316843.1//transmembrane protein 87B isoform 2 precursor [Homo sapiens]","1//3;2//1"]
[1111,2885,14.39,13.22,-0.122344415232606,0.0290140093543759,"*",0.01139382,"CHEK1","GO:0043231//intracellular membrane-bounded organelle;GO:0005654//nucleoplasm;GO:0000785//chromatin;GO:0005657//replication fork","GO:0035402//histone kinase activity (H3-T11 specific);GO:0005524//ATP binding","GO:0006997//nucleus organization;GO:0006281//DNA repair;GO:0000077//DNA damage checkpoint;GO:0042127//regulation of cell proliferation;GO:0048096//chromatin-mediated maintenance of transcription;GO:1902742//apoptotic process involved in development;GO:0007093//mitotic cell cycle checkpoint;GO:0010767//regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage;GO:0001833//inner cell mass cell proliferation;GO:2000615//regulation of histone H3-K9 acetylation;GO:0000086//G2/M transition of mitotic cell cycle","K02216//serine/threonine-protein kinase Chk1 [EC:2.7.11.1]","XP_017747798.1//PREDICTED: serine/threonine-protein kinase Chk1 isoform X3 [Rhinopithecus bieti];XP_004052424.1//PREDICTED: serine/threonine-protein kinase Chk1 isoform X1 [Gorilla gorilla gorilla];NP_001317356.1//serine/threonine-protein kinase Chk1 isoform 3 [Homo sapiens]","1//3;2//1;5"]
[3326,2650,597.76,549.38,-0.121761969633629,{"v":2.08922450750695e-15,"d":"2.09E-15"},"*",{"v":1.411214e-16,"d":"1.41E-16"},"HSP90AB1","GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0031526//brush border membrane;GO:1990917//ooplasm;GO:0042470//melanosome;GO:0016234//inclusion body;GO:0005737//cytoplasm;GO:0008180//COP9 signalosome;GO:0005829//cytosol;GO:0005576//extracellular region;GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0070062//extracellular exosome;GO:0005765//lysosomal membrane;GO:0005634//nucleus;GO:0009986//cell surface;GO:1990913//sperm head plasma membrane;GO:0034751//aryl hydrocarbon receptor complex","GO:0030235//nitric-oxide synthase regulator activity;GO:0005524//ATP binding;GO:0031072//heat shock protein binding;GO:0070182//DNA polymerase binding;GO:0043008//ATP-dependent protein binding;GO:0003725//double-stranded RNA binding;GO:0019901//protein kinase binding;GO:0046983//protein dimerization activity;GO:0008144//drug binding;GO:0019887//protein kinase regulator activity;GO:0019900//kinase binding;GO:0032564//dATP binding;GO:0002134//UTP binding;GO:0017098//sulfonylurea receptor binding;GO:0042826//histone deacetylase binding;GO:0002135//CTP binding;GO:0042277//peptide binding;GO:0042803//protein homodimerization activity;GO:0045296//cadherin binding;GO:0023026//MHC class II protein complex binding;GO:0030911//TPR domain binding;GO:0044325//ion channel binding;GO:1990226//histone methyltransferase binding;GO:0051082//unfolded protein binding;GO:0005525//GTP binding;GO:0097718//disordered domain specific binding","GO:0035690//cellular response to drug;GO:0051973//positive regulation of telomerase activity;GO:0001890//placenta development;GO:0032092//positive regulation of protein binding;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0060334//regulation of interferon-gamma-mediated signaling pathway;GO:0019062//virion attachment to host cell;GO:0071157//negative regulation of cell cycle arrest;GO:0045597//positive regulation of cell differentiation;GO:1903660//negative regulation of complement-dependent cytotoxicity;GO:1901389//negative regulation of transforming growth factor beta activation;GO:1905323//telomerase holoenzyme complex assembly;GO:0006457//protein folding;GO:0031396//regulation of protein ubiquitination;GO:0043524//negative regulation of neuron apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0045793//positive regulation of cell size;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:2000010//positive regulation of protein localization to cell surface;GO:0006950//response to stress;GO:0071407//cellular response to organic cyclic compound;GO:0007004//telomere maintenance via telomerase;GO:0009651//response to salt stress;GO:0071353//cellular response to interleukin-4;GO:0033160//positive regulation of protein import into nucleus, translocation;GO:0032516//positive regulation of phosphoprotein phosphatase activity;GO:0051131//chaperone-mediated protein complex assembly;GO:0060338//regulation of type I interferon-mediated signaling pathway;GO:0097435//supramolecular fiber organization;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0042220//response to cocaine","K04079//molecular chaperone HtpG","NP_001258901.1//heat shock protein HSP 90-beta isoform c [Homo sapiens];NP_031381.2//heat shock protein HSP 90-beta isoform a [Homo sapiens];NP_001258900.1//heat shock protein HSP 90-beta isoform b [Homo sapiens]","1//3;3//A2MP1"]
[79085,3475,31.14,28.62,-0.121745272352369,0.0789589758754864,"*",0.0355696,"SLC25A23","NA","NA","NA","K14684//solute carrier family 25 (mitochondrial phosphate transporter), member 23/24/25/41","XP_022381519.1//calcium-binding mitochondrial carrier protein SCaMC-3 isoform X1 [Enhydra lutris kenyoni]","2//1"]
[57727,3154,20.14,18.52,-0.120979584746548,0.180507536097503,"*",0.0945704,"NCOA5","GO:0005634//nucleus;GO:0005615//extracellular space;GO:0015629//actin cytoskeleton","GO:0003723//RNA binding;GO:0003682//chromatin binding","GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0042593//glucose homeostasis","K10624//E3 ubiquitin-protein ligase RBBP6 [EC:2.3.2.27];K17585//phosphatase and actin regulator 4;K19756//radial spoke head protein 4A;K20102//YTH domain-containing family protein","NP_001335078.1//nuclear receptor coactivator 5 isoform 3 [Homo sapiens];NP_001335079.1//nuclear receptor coactivator 5 isoform 4 [Homo sapiens];AAG36793.1//nuclear receptor coactivator CIA, partial [Homo sapiens]","1//3;2//1"]
[64895,7386,3,2.76,-0.120294233717712,0.486042259536412,"*",0.33342,"PAPOLG","GO:0016020//membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0005829//cytosol","GO:0003723//RNA binding;GO:0004652//polynucleotide adenylyltransferase activity;GO:0046872//metal ion binding;GO:0005524//ATP binding","GO:0031123//RNA 3'-end processing;GO:0043631//RNA polyadenylation;GO:0006378//mRNA polyadenylation","K14376//poly(A) polymerase [EC:2.7.7.19]","NP_075045.2//poly(A) polymerase gamma [Homo sapiens]","3//A2MP1"]
[1659,4264,15.15,13.94,-0.12008723249189,0.169109015879932,"*",0.0874658,"DHX8","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0016604//nuclear body;GO:0005737//cytoplasm;GO:0071013//catalytic step 2 spliceosome","GO:0003723//RNA binding;GO:0004004//ATP-dependent RNA helicase activity;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0004386//helicase activity;GO:0003676//nucleic acid binding","GO:0006396//RNA processing;GO:0000398//mRNA splicing, via spliceosome;GO:0008380//RNA splicing","K12818//ATP-dependent RNA helicase DHX8/PRP22 [EC:3.6.4.13]","NP_001309150.1//ATP-dependent RNA helicase DHX8 isoform 8 [Homo sapiens];XP_016787218.1//PREDICTED: ATP-dependent RNA helicase DHX8 isoform X6 [Pan troglodytes];NP_001309147.1//ATP-dependent RNA helicase DHX8 isoform 5 [Homo sapiens];NP_001289552.1//ATP-dependent RNA helicase DHX8 isoform 2 [Homo sapiens];NP_004932.1//ATP-dependent RNA helicase DHX8 isoform 1 [Homo sapiens];NP_001309149.1//ATP-dependent RNA helicase DHX8 isoform 7 [Homo sapiens];NP_001309148.1//ATP-dependent RNA helicase DHX8 isoform 6 [Homo sapiens];XP_009249960.1//PREDICTED: ATP-dependent RNA helicase DHX8 isoform X1 [Pongo abelii]","1//3;2//1"]
[64431,2491,6.16,5.67,-0.119581615752673,0.602509080128748,"*",0.4453,"ACTR6","GO:0005634//nucleus","NA","GO:0006338//chromatin remodeling","K11662//actin-related protein 6","XP_005572035.1//PREDICTED: actin-related protein 6 isoform X1 [Macaca fascicularis]",4]
[56940,2087,7.31,6.73,-0.11926490134212,0.591600924412666,"*",0.43509,"DUSP22","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity","GO:0046330//positive regulation of JNK cascade;GO:0002710//negative regulation of T cell mediated immunity;GO:0042127//regulation of cell proliferation;GO:0000188//inactivation of MAPK activity;GO:0006915//apoptotic process;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0050860//negative regulation of T cell receptor signaling pathway;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0007275//multicellular organism development;GO:0006470//protein dephosphorylation;GO:0050868//negative regulation of T cell activation","K14165//atypical dual specificity phosphatase [EC:3.1.3.16 3.1.3.48]","NP_001273484.1//dual specificity protein phosphatase 22 isoform a [Homo sapiens];NP_064570.1//dual specificity protein phosphatase 22 isoform b [Homo sapiens]","4;1//3"]
[23256,2111,16.77,15.45,-0.118275850772609,0.118033073116037,"*",0.0566742,"SCFD1","GO:0032580//Golgi cisterna membrane;GO:0017119//Golgi transport complex;GO:0005829//cytosol;GO:0005798//Golgi-associated vesicle;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005801//cis-Golgi network","GO:0047485//protein N-terminus binding;GO:0019905//syntaxin binding","GO:0000902//cell morphogenesis;GO:1902902//negative regulation of autophagosome assembly;GO:0006904//vesicle docking involved in exocytosis;GO:0048208//COPII vesicle coating;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0009636//response to toxic substance;GO:0001666//response to hypoxia;GO:0060628//regulation of ER to Golgi vesicle-mediated transport;GO:0051223//regulation of protein transport;GO:1901998//toxin transport;GO:0006892//post-Golgi vesicle-mediated transport;GO:0015031//protein transport;GO:0006909//phagocytosis","K19998//sec1 family domain-containing protein 1","NP_001269961.1//sec1 family domain-containing protein 1 isoform e [Homo sapiens];XP_017751375.1//PREDICTED: sec1 family domain-containing protein 1 isoform X1 [Rhinopithecus bieti];XP_022277586.1//sec1 family domain-containing protein 1 isoform X3 [Canis lupus familiaris]","1//3;3//A2MP1;2//1"]
[51538,1514,14.93,13.76,-0.117733695432443,0.656121301177052,"*",0.499012,"ZCCHC17","GO:0005730//nucleolus;GO:0030529//intracellular ribonucleoprotein complex;GO:0022625//cytosolic large ribosomal subunit","GO:0003723//RNA binding;GO:0008270//zinc ion binding;GO:0003676//nucleic acid binding","NA","K10624//E3 ubiquitin-protein ligase RBBP6 [EC:2.3.2.27];K13171//serine/arginine repetitive matrix protein 1","XP_019692111.1//PREDICTED: nucleolar protein of 40 kDa isoform X1 [Felis catus];NP_001269502.1//nucleolar protein of 40 kDa isoform h [Homo sapiens];NP_001269496.1//nucleolar protein of 40 kDa isoform b [Homo sapiens];NP_001269500.1//nucleolar protein of 40 kDa isoform f [Homo sapiens];NP_001269495.1//nucleolar protein of 40 kDa isoform a [Homo sapiens];NP_001269501.1//nucleolar protein of 40 kDa isoform g [Homo sapiens];NP_001269498.1//nucleolar protein of 40 kDa isoform d [Homo sapiens]","1//3;3//A2MP1"]
[23603,3858,57,52.54,-0.117545718805835,0.0110644610059066,"*",0.00386986,"CORO1C","GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0016328//lateral plasma membrane;GO:0016600//flotillin complex;GO:0031982//vesicle;GO:0030027//lamellipodium;GO:0005737//cytoplasm","GO:0051015//actin filament binding;GO:0048365//Rac GTPase binding","GO:0010632//regulation of epithelial cell migration;GO:2000394//positive regulation of lamellipodium morphogenesis;GO:0010762//regulation of fibroblast migration;GO:0010633//negative regulation of epithelial cell migration;GO:0001932//regulation of protein phosphorylation;GO:0051893//regulation of focal adhesion assembly;GO:1900027//regulation of ruffle assembly;GO:0006909//phagocytosis;GO:0045184//establishment of protein localization;GO:0090630//activation of GTPase activity;GO:0007165//signal transduction;GO:0030036//actin cytoskeleton organization;GO:1900025//negative regulation of substrate adhesion-dependent cell spreading;GO:0001755//neural crest cell migration;GO:0051895//negative regulation of focal adhesion assembly;GO:1900024//regulation of substrate adhesion-dependent cell spreading;GO:0001933//negative regulation of protein phosphorylation;GO:0044387//negative regulation of protein kinase activity by regulation of protein phosphorylation","K13886//coronin-1B/1C/6","XP_008002778.1//PREDICTED: coronin-1C isoform X1 [Chlorocebus sabaeus];NP_001098707.1//coronin-1C isoform a [Homo sapiens]","1//3;3//A2MP1;2//1"]
[8908,3182,3.98,3.67,-0.116988367700436,0.533430445382586,"*",0.379686,"GYG2","GO:0005829//cytosol;GO:0043202//lysosomal lumen","GO:0102751//UDP-alpha-D-glucose:glucosyl-glycogenin alpha-D-glucosyltransferase activity;GO:0016757//transferase activity, transferring glycosyl groups;GO:0008466//glycogenin glucosyltransferase activity","GO:0005980//glycogen catabolic process;GO:0005978//glycogen biosynthetic process","K00750//glycogenin [EC:2.4.1.186]","NP_003909.2//glycogenin-2 isoform b [Homo sapiens];NP_001171631.1//glycogenin-2 isoform c [Homo sapiens];NP_001171632.1//glycogenin-2 isoform d [Homo sapiens];NP_001073324.1//glycogenin-2 isoform a [Homo sapiens]","1//3;2//1"]
[29889,2428,15.93,14.7,-0.115930111801583,0.285412021507234,"*",0.1654868,"GNL2","GO:0016020//membrane;GO:0005634//nucleus;GO:0005730//nucleolus","GO:0003723//RNA binding;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0042254//ribosome biogenesis","K14537//nuclear GTP-binding protein","NP_037417.1//nucleolar GTP-binding protein 2 isoform 1 [Homo sapiens];NP_001310553.1//nucleolar GTP-binding protein 2 isoform 3 [Homo sapiens];NP_001310552.1//nucleolar GTP-binding protein 2 isoform 2 [Homo sapiens]","1//3;2//1"]
[55211,2527,0.91,0.84,-0.115477217419936,0.862774371076462,"*",0.793262,"DPPA4","GO:0005654//nucleoplasm","NA","GO:0006355//regulation of transcription, DNA-templated;GO:0060484//lung-associated mesenchyme development;GO:0006351//transcription, DNA-templated;GO:0035019//somatic stem cell population maintenance","K09228//KRAB domain-containing zinc finger protein;K12022//tripartite motif-containing protein 46;K01368//cathepsin S [EC:3.4.22.27];K11447//histone demethylase [EC:1.14.11.-]","NP_001335858.1//developmental pluripotency-associated protein 4 isoform 3 [Homo sapiens];NP_060659.3//developmental pluripotency-associated protein 4 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[84126,2526,7.58,7,-0.114842926338763,0.378381019167085,"*",0.236044,"ATRIP","GO:0005654//nucleoplasm","GO:0070530//K63-linked polyubiquitin modification-dependent protein binding;GO:0004527//exonuclease activity","GO:1901796//regulation of signal transduction by p53 class mediator;GO:0006260//DNA replication;GO:0000077//DNA damage checkpoint;GO:0036297//interstrand cross-link repair","K10905//ATR interacting protein","NP_569055.1//ATR-interacting protein isoform 1 [Homo sapiens];NP_115542.2//ATR-interacting protein isoform 2 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[9949,5335,3.68,3.4,-0.114171019919311,0.477731866495507,"*",0.326164,"AMMECR1","GO:0005634//nucleus","NA","NA","K10385//loricrin;K02184//formin 2","XP_007990756.1//PREDICTED: AMME syndrome candidate gene 1 protein isoform X2 [Chlorocebus sabaeus];XP_007990755.1//PREDICTED: AMME syndrome candidate gene 1 protein isoform X1 [Chlorocebus sabaeus];NP_001128965.1//AMME syndrome candidate gene 1 protein homolog [Pongo abelii]","1//3;2//1"]
[140825,1440,0.79,0.73,-0.113956189297086,0.911133163718881,"*",0.854608,"NEURL2","GO:0005829//cytosol;GO:0005622//intracellular","NA","GO:0043687//post-translational protein modification;GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction","K16782//neuralized-like protein 2","NP_001265464.1//neuralized-like protein 2 isoform 2 [Homo sapiens];NP_542787.1//neuralized-like protein 2 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[9921,3864,40.93,37.84,-0.11324657810369,0.0438207739567048,"*",0.01824814,"RNF10","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0044212//transcription regulatory region DNA binding;GO:0004842//ubiquitin-protein transferase activity","GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0051865//protein autoubiquitination;GO:0006351//transcription, DNA-templated;GO:0031643//positive regulation of myelination;GO:0010626//negative regulation of Schwann cell proliferation;GO:0045893//positive regulation of transcription, DNA-templated","K15177//RNA polymerase-associated protein LEO1","NP_001317403.1//RING finger protein 10 isoform 2 [Homo sapiens];BAG63094.1//unnamed protein product [Homo sapiens]","1//3;4"]
[9341,2225,37.25,34.44,-0.113155282840042,0.170425336875151,"*",0.08836,"VAMP3","GO:0016324//apical plasma membrane;GO:0030054//cell junction;GO:0032588//trans-Golgi network membrane;GO:0055038//recycling endosome membrane;GO:0005829//cytosol;GO:0030665//clathrin-coated vesicle membrane;GO:0016021//integral component of membrane;GO:0045202//synapse;GO:0055037//recycling endosome;GO:0005886//plasma membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0030136//clathrin-coated vesicle;GO:0005622//intracellular;GO:0030670//phagocytic vesicle membrane;GO:0043005//neuron projection;GO:0048471//perinuclear region of cytoplasm;GO:0009986//cell surface;GO:0030141//secretory granule;GO:0030133//transport vesicle;GO:0031201//SNARE complex","GO:0017075//syntaxin-1 binding;GO:0000149//SNARE binding;GO:0005484//SNAP receptor activity","GO:0035493//SNARE complex assembly;GO:0034446//substrate adhesion-dependent cell spreading;GO:0001921//positive regulation of receptor recycling;GO:0006904//vesicle docking involved in exocytosis;GO:0042147//retrograde transport, endosome to Golgi;GO:0017156//calcium ion regulated exocytosis;GO:0016192//vesicle-mediated transport;GO:0061024//membrane organization;GO:1903531//negative regulation of secretion by cell;GO:0006906//vesicle fusion;GO:0061025//membrane fusion;GO:0043001//Golgi to plasma membrane protein transport;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0006461//protein complex assembly;GO:0006887//exocytosis","K13505//vesicle-associated membrane protein 3","XP_009233879.1//PREDICTED: vesicle-associated membrane protein 3 isoform X1 [Pongo abelii]","3//A2MP1"]
[50865,1221,29.4,27.19,-0.112740003698967,0.411444010335917,"*",0.269136,"HEBP1","GO:0070062//extracellular exosome","NA","NA","K01942//biotin---protein ligase [EC:6.3.4.9 6.3.4.10 6.3.4.11 6.3.4.15]","XP_003778029.2//PREDICTED: LOW QUALITY PROTEIN: heme-binding protein 1 [Pongo abelii]",4]
[51588,3225,11.24,10.4,-0.112058507192472,0.40565370338248,"*",0.26352,"PIAS4","GO:0016605//PML body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:1990234//transferase complex;GO:0016363//nuclear matrix;GO:0005737//cytoplasm","GO:0061665//SUMO ligase activity;GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0008022//protein C-terminus binding;GO:0008270//zinc ion binding;GO:0031625//ubiquitin protein ligase binding;GO:0019789//SUMO transferase activity","GO:0045892//negative regulation of transcription, DNA-templated;GO:0016925//protein sumoylation;GO:0010804//negative regulation of tumor necrosis factor-mediated signaling pathway;GO:1902231//positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage;GO:0006351//transcription, DNA-templated;GO:0033235//positive regulation of protein sumoylation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0016055//Wnt signaling pathway;GO:1902174//positive regulation of keratinocyte apoptotic process;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0032088//negative regulation of NF-kappaB transcription factor activity","K16065//E3 SUMO-protein ligase PIAS4","NP_056981.2//E3 SUMO-protein ligase PIAS4 [Homo sapiens]","3//A2MP1"]
[400709,3910,2.68,2.48,-0.111892880070897,0.661399579414239,"*",0.54145,"SIGLEC16","NA","NA","NA","K06750//sialic acid binding Ig-like lectin 11","XP_009434343.2//PREDICTED: sialic acid-binding Ig-like lectin 16 isoform X1 [Pan troglodytes]","1//3"]
[126308,3347,13.34,12.35,-0.111247624712545,0.363607304471256,"*",0.224506,"MOB3A","GO:0005622//intracellular","GO:0046872//metal ion binding;GO:0016301//kinase activity","NA","K06685//MOB kinase activator 1","NP_570719.1//MOB kinase activator 3A [Homo sapiens]","2//1"]
[57154,5700,11.36,10.52,-0.11082813021238,0.240031598035056,"*",0.1345914,"SMURF1","GO:0070062//extracellular exosome;GO:0030424//axon;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0043025//neuronal cell body","GO:0061630//ubiquitin protein ligase activity;GO:0048185//activin binding;GO:0070412//R-SMAD binding;GO:0070411//I-SMAD binding;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0005543//phospholipid binding","GO:0061734//parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization;GO:0030514//negative regulation of BMP signaling pathway;GO:0016567//protein ubiquitination;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0061736//engulfment of target by autophagosome;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0006511//ubiquitin-dependent protein catabolic process;GO:2000060//positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0006611//protein export from nucleus;GO:0071211//protein targeting to vacuole involved in autophagy;GO:0000209//protein polyubiquitination;GO:0061753//substrate localization to autophagosome;GO:0032801//receptor catabolic process;GO:0030154//cell differentiation;GO:0072659//protein localization to plasma membrane;GO:0030509//BMP signaling pathway;GO:0007398//ectoderm development;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0030579//ubiquitin-dependent SMAD protein catabolic process;GO:0030279//negative regulation of ossification;GO:1903861//positive regulation of dendrite extension;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0034394//protein localization to cell surface","K04678//E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]","NP_065162.1//E3 ubiquitin-protein ligase SMURF1 isoform 1 [Homo sapiens];NP_001186776.1//E3 ubiquitin-protein ligase SMURF1 isoform 3 [Homo sapiens];NP_851994.1//E3 ubiquitin-protein ligase SMURF1 isoform 2 [Homo sapiens]","1//3;2//1"]
[7335,2266,143.75,133.2,-0.109967873647838,0.00313271871356378,"*",0.000970174,"UBE2V1","GO:0035370//UBC13-UEV1A complex;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0031371//ubiquitin conjugating enzyme complex;GO:0000151//ubiquitin ligase complex;GO:0005829//cytosol;GO:0043234//protein complex","GO:0061630//ubiquitin protein ligase activity;GO:0031625//ubiquitin protein ligase binding","GO:0070534//protein K63-linked ubiquitination;GO:0070423//nucleotide-binding oligomerization domain containing signaling pathway;GO:0030154//cell differentiation;GO:0000187//activation of MAPK activity;GO:0050852//T cell receptor signaling pathway;GO:0006355//regulation of transcription, DNA-templated;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0007254//JNK cascade;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0006282//regulation of DNA repair;GO:0000209//protein polyubiquitination;GO:0006301//postreplication repair","K20656//transmembrane protein 189;K10704//ubiquitin-conjugating enzyme E2 variant","NP_071887.1//ubiquitin-conjugating enzyme E2 variant 1 isoform c [Homo sapiens];XP_015747055.1//PREDICTED: ubiquitin-conjugating enzyme E2 variant 1 isoform X1 [Python bivittatus];AAC02755.1//UEV1Bs, partial [Homo sapiens];XP_017827131.1//PREDICTED: ubiquitin-conjugating enzyme E2 variant 1 isoform X1 [Callithrix jacchus];XP_018872625.1//PREDICTED: ubiquitin-conjugating enzyme E2 variant 1 isoform X2 [Gorilla gorilla gorilla];XP_018872626.1//PREDICTED: ubiquitin-conjugating enzyme E2 variant 1 isoform X3 [Gorilla gorilla gorilla];XP_007423105.1//PREDICTED: ubiquitin-conjugating enzyme E2 variant 1 isoform X2 [Python bivittatus];XP_020839863.1//ubiquitin-conjugating enzyme E2 variant 1 isoform X2 [Phascolarctos cinereus];XP_014420422.1//PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein LOC102516405 [Camelus ferus];XP_008012503.1//PREDICTED: ubiquitin-conjugating enzyme E2 variant 1 isoform X1 [Chlorocebus sabaeus]","1//3;2//1;5"]
[54529,2487,14.15,13.12,-0.109034333101161,0.430514426893939,"*",0.284602,"ASNSD1","NA","GO:0042803//protein homodimerization activity;GO:0004066//asparagine synthase (glutamine-hydrolyzing) activity","GO:0006541//glutamine metabolic process;GO:0006529//asparagine biosynthetic process","K06825//fibrillin 1","NP_001340427.1//asparagine synthetase domain-containing protein 1 [Homo sapiens]","1//3;3//A2MP1"]
[252969,2238,9.5,8.81,-0.108785494297897,0.81736152657946,"*",0.73539,"NEIL2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005876//spindle microtubule","GO:0003906//DNA-(apurinic or apyrimidinic site) lyase activity;GO:0016799//hydrolase activity, hydrolyzing N-glycosyl compounds;GO:0008017//microtubule binding;GO:0003684//damaged DNA binding;GO:0140078//class I DNA-(apurinic or apyrimidinic site) lyase activity;GO:0019104//DNA N-glycosylase activity;GO:0008270//zinc ion binding;GO:0140080//class III/IV DNA-(apurinic or apyrimidinic site) lyase activity","GO:0006284//base-excision repair;GO:0045008//depyrimidination;GO:0006289//nucleotide-excision repair","K10568//endonuclease VIII-like 2 [EC:3.2.2.- 4.2.99.18]","NP_001129220.1//endonuclease 8-like 2 isoform c [Homo sapiens];XP_001142056.1//PREDICTED: endonuclease 8-like 2 isoform X1 [Pan troglodytes]","1//3;3//A2MP1;2//1"]
[10193,5205,10.94,10.15,-0.108133010720018,0.298570601326487,"*",0.1747238,"RNF41","GO:0071782//endoplasmic reticulum tubular network;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm","GO:0005135//interleukin-3 receptor binding;GO:0061630//ubiquitin protein ligase activity;GO:0005128//erythropoietin receptor binding;GO:0030971//receptor tyrosine kinase binding;GO:0004842//ubiquitin-protein transferase activity;GO:0031386//protein tag;GO:0046872//metal ion binding;GO:0019904//protein domain specific binding;GO:0016881//acid-amino acid ligase activity;GO:0008270//zinc ion binding;GO:0017160//Ral GTPase binding","GO:0097191//extrinsic apoptotic signaling pathway;GO:0016567//protein ubiquitination;GO:0051896//regulation of protein kinase B signaling;GO:0045637//regulation of myeloid cell differentiation;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0051865//protein autoubiquitination;GO:0006914//autophagy;GO:0010498//proteasomal protein catabolic process;GO:0045619//regulation of lymphocyte differentiation;GO:0000209//protein polyubiquitination;GO:0008285//negative regulation of cell proliferation;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0030336//negative regulation of cell migration;GO:0043408//regulation of MAPK cascade;GO:2000114//regulation of establishment of cell polarity;GO:0045732//positive regulation of protein catabolic process;GO:1901525//negative regulation of mitophagy;GO:2000377//regulation of reactive oxygen species metabolic process","K11981//E3 ubiquitin-protein ligase NRDP1 [EC:2.3.2.27]","XP_003906635.1//E3 ubiquitin-protein ligase NRDP1 isoform X2 [Papio anubis];NP_005776.1//E3 ubiquitin-protein ligase NRDP1 isoform 1 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[4720,2062,47.06,43.68,-0.107528464304445,0.16135977254902,"*",0.0829426,"NDUFS2","GO:0005759//mitochondrial matrix;GO:0005654//nucleoplasm;GO:0005747//mitochondrial respiratory chain complex I;GO:0005739//mitochondrion","GO:0009055//electron transfer activity;GO:0046872//metal ion binding;GO:0003954//NADH dehydrogenase activity;GO:0031625//ubiquitin protein ligase binding;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0048038//quinone binding;GO:0051287//NAD binding;GO:0008137//NADH dehydrogenase (ubiquinone) activity","GO:0006979//response to oxidative stress;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0042775//mitochondrial ATP synthesis coupled electron transport","K03935//NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:1.6.5.3 1.6.99.3]","ELV13286.1//NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial [Tupaia chinensis]","1//3;4"]
[8927,15964,0.14,0.13,-0.106915203916512,0.862833119161106,"*",0.793262,"BSN","GO:0030425//dendrite;GO:0030424//axon;GO:0048786//presynaptic active zone;GO:0005634//nucleus;GO:0060076//excitatory synapse;GO:0030054//cell junction;GO:0014069//postsynaptic density;GO:0048788//cytoskeleton of presynaptic active zone;GO:0009986//cell surface;GO:0044306//neuron projection terminus","GO:0046872//metal ion binding","GO:0007416//synapse assembly;GO:0035418//protein localization to synapse;GO:0099526//presynapse to nucleus signaling pathway;GO:0007268//chemical synaptic transmission","K16882//protein piccolo","NP_003449.2//protein bassoon [Homo sapiens]","3//A2MP1"]
[6185,2532,124.79,115.89,-0.106746245600669,0.00252001491172214,"*",0.000763072,"RPN2","GO:0016020//membrane;GO:0008250//oligosaccharyltransferase complex;GO:0005791//rough endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0000421//autophagosome membrane","GO:0043022//ribosome binding","GO:0042493//response to drug;GO:0018279//protein N-linked glycosylation via asparagine;GO:0006464//cellular protein modification process;GO:0006487//protein N-linked glycosylation;GO:0007568//aging","K12667//oligosaccharyltransferase complex subunit delta (ribophorin II)","NP_001311233.1//dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 isoform 7 precursor [Homo sapiens];EFB14847.1//hypothetical protein PANDA_003175, partial [Ailuropoda melanoleuca];NP_001311235.1//dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 isoform 9 [Homo sapiens];NP_001129243.1//dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 isoform 2 precursor [Homo sapiens];NP_001311234.1//dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 isoform 8 precursor [Homo sapiens];NP_001311232.1//dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 isoform 6 precursor [Homo sapiens];NP_001311228.1//dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 isoform 3 precursor [Homo sapiens];NP_001311231.1//dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 isoform 5 precursor [Homo sapiens];NP_001311230.1//dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 isoform 4 precursor [Homo sapiens]","4;1//3;2//1"]
[2145,4677,7.87,7.31,-0.106492229555049,0.425095685572897,"*",0.279636,"EZH1","GO:0005654//nucleoplasm;GO:0035098//ESC/E(Z) complex","GO:0003682//chromatin binding;GO:0018024//histone-lysine N-methyltransferase activity","GO:0070734//histone H3-K27 methylation;GO:0009653//anatomical structure morphogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0021766//hippocampus development;GO:0006351//transcription, DNA-templated","K17451//histone-lysine N-methyltransferase EZH1 [EC:2.1.1.43]","XP_005257202.1//PREDICTED: histone-lysine N-methyltransferase EZH1 isoform X2 [Homo sapiens];XP_011522819.1//PREDICTED: histone-lysine N-methyltransferase EZH1 isoform X1 [Homo sapiens];NP_001308008.1//histone-lysine N-methyltransferase EZH1 isoform 2 [Homo sapiens]","1//3;4"]
[1431,2997,129.59,120.43,-0.105759572037377,0.00188477615609756,"*",0.000556324,"CS","GO:0005759//mitochondrial matrix;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005739//mitochondrion","GO:0003723//RNA binding;GO:0004108//citrate (Si)-synthase activity","GO:0006099//tricarboxylic acid cycle;GO:0005975//carbohydrate metabolic process","K01647//citrate synthase [EC:2.3.3.1]","XP_011822625.1//PREDICTED: citrate synthase, mitochondrial isoform X1 [Mandrillus leucophaeus]","2//1"]
[55633,3545,4.7,4.37,-0.105027477064401,0.624910562244302,"*",0.468546,"TBC1D22B","GO:0012505//endomembrane system;GO:0005622//intracellular","GO:0071889//14-3-3 protein binding;GO:0017137//Rab GTPase binding;GO:0005096//GTPase activator activity","GO:0006886//intracellular protein transport;GO:0090630//activation of GTPase activity;GO:0031338//regulation of vesicle fusion","K20360//TBC1 domain family member 2","XP_003128420.3//TBC1 domain family member 22B [Sus scrofa]","3//A2MP1"]
[221710,4710,3.43,3.19,-0.104652152407943,0.650096069631219,"*",0.49329,"SMIM13","GO:0016021//integral component of membrane","NA","NA","K17399//DNA (cytosine-5)-methyltransferase 3B [EC:2.1.1.37];K20478//golgin subfamily B member 1","EAW55298.1//hCG2040263, isoform CRA_b [Homo sapiens]","1//3"]
[51090,1514,1.44,1.34,-0.10383581098454,0.859629259971364,"*",0.789294,"PLLP","GO:0070062//extracellular exosome;GO:0043218//compact myelin;GO:0045121//membrane raft;GO:0016021//integral component of membrane","GO:0019911//structural constituent of myelin sheath","GO:0009611//response to wounding;GO:0042552//myelination;GO:0001766//membrane raft polarization;GO:0008104//protein localization;GO:0006811//ion transport","NA","NP_057077.1//plasmolipin [Homo sapiens]","2//1"]
[27152,3275,0.29,0.27,-0.103093492964103,0.901666860856167,"*",0.842568,"INTU","GO:0036064//ciliary basal body;GO:0009986//cell surface;GO:0031514//motile cilium;GO:0005737//cytoplasm","NA","GO:0007399//nervous system development;GO:0010839//negative regulation of keratinocyte proliferation;GO:0051782//negative regulation of cell division;GO:0008589//regulation of smoothened signaling pathway;GO:0030216//keratinocyte differentiation;GO:1905515//non-motile cilium assembly;GO:0044458//motile cilium assembly;GO:0030278//regulation of ossification;GO:0042733//embryonic digit morphogenesis;GO:0060271//cilium assembly;GO:0021513//spinal cord dorsal/ventral patterning;GO:0031069//hair follicle morphogenesis;GO:0060173//limb development;GO:0045880//positive regulation of smoothened signaling pathway;GO:0021915//neural tube development","K07820//beta-1,3-galactosyltransferase 2 [EC:2.4.1.86]","NP_056508.2//protein inturned [Homo sapiens]","3//A2MP1"]
[57701,4918,6.82,6.35,-0.103015147364644,0.475831131583777,"*",0.324628,"NCKAP5L","GO:0035371//microtubule plus-end;GO:0005813//centrosome;GO:0005737//cytoplasm","NA","GO:0007019//microtubule depolymerization;GO:0001578//microtubule bundle formation","K06237//collagen, type IV, alpha;K18401//KAT8 regulatory NSL complex subunit 2;K06236//collagen, type I, alpha;K19720//collagen, type III, alpha","NP_001032895.2//nck-associated protein 5-like [Homo sapiens]","3//A2MP1"]
[6451,2090,16.88,15.73,-0.101796233291498,0.46736656423499,"*",0.317244,"SH3BGRL","GO:0070062//extracellular exosome;GO:0005737//cytoplasm","NA","NA","K13912//deleted in malignant brain tumors 1 protein","XP_004407393.1//PREDICTED: SH3 domain-binding glutamic acid-rich-like protein [Odobenus rosmarus divergens]","2//1"]
[286128,4620,9.66,9.01,-0.100496083022235,0.661576907408823,"*",0.541678,"ZFP41","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_021570783.1//LOW QUALITY PROTEIN: uncharacterized protein LOC103266035, partial [Carlito syrichta]","2//1;5"]
[55341,3589,12.35,11.52,-0.100370325029728,0.402036248816768,"*",0.260566,"LSG1","GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0015030//Cajal body","GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0051168//nuclear export","K14539//large subunit GTPase 1 [EC:3.6.1.-]","XP_003895355.1//large subunit GTPase 1 homolog [Papio anubis]","2//1"]
[203100,2130,1.94,1.81,-0.100066955103922,0.84695122506183,"*",0.771768,"HTRA4","GO:0005576//extracellular region","GO:0004252//serine-type endopeptidase activity;GO:0005520//insulin-like growth factor binding;GO:0004175//endopeptidase activity","GO:0001558//regulation of cell growth;GO:0006508//proteolysis;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway","K08786//HtrA serine peptidase 4 [EC:3.4.21.-]","NP_710159.1//serine protease HTRA4 precursor [Homo sapiens]","3//A2MP1"]
[6949,4911,44.74,41.76,-0.0994435444892345,0.0166126326639344,"*",0.00609012,"TCOF1","GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0001650//fibrillar center","GO:0003723//RNA binding;GO:0001042//RNA polymerase I core binding;GO:0046982//protein heterodimerization activity;GO:0005215//transporter activity","GO:0014032//neural crest cell development;GO:0014029//neural crest formation;GO:0001501//skeletal system development;GO:0006417//regulation of translation","K14562//Treacher Collins syndrome protein","NP_001128717.1//treacle protein isoform f [Homo sapiens];NP_001128716.1//treacle protein isoform e [Homo sapiens];NP_000347.2//treacle protein isoform b [Homo sapiens];NP_001008657.1//treacle protein isoform c [Homo sapiens];NP_001128715.1//treacle protein isoform d [Homo sapiens];NP_001182070.1//treacle protein isoform g [Homo sapiens]","1//3;3//A2MP1;2//1"]
[22800,2350,12.78,11.93,-0.0992937932517663,0.525475457742079,"*",0.368596,"RRAS2","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005783//endoplasmic reticulum;GO:0005925//focal adhesion;GO:0005622//intracellular;GO:0005886//plasma membrane","GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0001649//osteoblast differentiation;GO:0007165//signal transduction;GO:0030335//positive regulation of cell migration;GO:0009987//cellular process;GO:1901214//regulation of neuron death;GO:0007265//Ras protein signal transduction","K07830//Ras-related protein R-Ras2","XP_004752081.2//PREDICTED: ras-related protein R-Ras2 isoform X1 [Mustela putorius furo];XP_009244868.1//PREDICTED: ras-related protein R-Ras2 [Pongo abelii];XP_003781167.1//PREDICTED: ras-related protein R-Ras2 isoform X1 [Otolemur garnettii];NP_036382.2//ras-related protein R-Ras2 isoform a [Homo sapiens]","1//3;2//1;5"]
[4784,5579,4.72,4.41,-0.0980082038043206,0.555279395150778,"*",0.4,"NFIX","GO:0005634//nucleus","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0003705//transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding","GO:0021549//cerebellum development;GO:0021680//cerebellar Purkinje cell layer development;GO:0006260//DNA replication;GO:0006351//transcription, DNA-templated;GO:0021707//cerebellar granule cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0048708//astrocyte differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter","K09171//nuclear factor I/X","XP_019519733.1//PREDICTED: nuclear factor 1 X-type isoform X1 [Hipposideros armiger];XP_004635598.1//PREDICTED: nuclear factor 1 X-type isoform X1 [Octodon degus]","3//A2MP1;2//1"]
[4355,4275,3.69,3.45,-0.0970244543948645,0.641308356652526,"*",0.520506,"MPP2","GO:0016020//membrane;GO:0005856//cytoskeleton;GO:0014069//postsynaptic density;GO:0005737//cytoplasm;GO:0043198//dendritic shaft;GO:0032590//dendrite membrane;GO:0005887//integral component of plasma membrane;GO:0043197//dendritic spine;GO:0032591//dendritic spine membrane","GO:0044325//ion channel binding;GO:0030165//PDZ domain binding;GO:0004385//guanylate kinase activity","GO:0007165//signal transduction;GO:0060291//long-term synaptic potentiation;GO:0051260//protein homooligomerization;GO:0060079//excitatory postsynaptic potential","K06103//calcium/calmodulin-dependent serine protein kinase [EC:2.7.11.1]","XP_012299369.1//MAGUK p55 subfamily member 2 isoform X4 [Aotus nancymaae];XP_011523129.2//PREDICTED: MAGUK p55 subfamily member 2 isoform X1 [Homo sapiens];XP_010361386.1//PREDICTED: MAGUK p55 subfamily member 2 isoform X1 [Rhinopithecus roxellana];NP_001265305.2//MAGUK p55 subfamily member 2 isoform 8 [Homo sapiens];NP_001265299.1//MAGUK p55 subfamily member 2 isoform 1 [Homo sapiens];XP_008010683.1//PREDICTED: MAGUK p55 subfamily member 2 isoform X1 [Chlorocebus sabaeus]","4;1//3;2//1"]
[132299,794,47.88,44.77,-0.0968908340399577,0.650657226327945,"*",0.493838,"OCIAD2","GO:0005768//endosome;GO:0005743//mitochondrial inner membrane","NA","NA","NA","NP_689611.1//OCIA domain-containing protein 2 isoform 2 [Homo sapiens];NP_001014446.1//OCIA domain-containing protein 2 isoform 1 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[11078,3951,17.23,16.12,-0.0960709576969808,0.696924583884546,"*",0.580436,"TRIOBP","GO:0005634//nucleus;GO:0005815//microtubule organizing center;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0005737//cytoplasm;GO:0030496//midbody","GO:0051015//actin filament binding;GO:0045159//myosin II binding;GO:0031625//ubiquitin protein ligase binding;GO:0017049//GTP-Rho binding","GO:0051301//cell division;GO:0051016//barbed-end actin filament capping;GO:0007049//cell cycle;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:0030047//actin modification","K10955//mucin-2;K16628//collagen, type VII, alpha;K03129//transcription initiation factor TFIID subunit 4;K22020//mucin-19;K20478//golgin subfamily B member 1","NP_001034230.1//TRIO and F-actin-binding protein isoform 6 [Homo sapiens];XP_016794638.1//PREDICTED: TRIO and F-actin-binding protein isoform X6 [Pan troglodytes];NP_619538.2//TRIO and F-actin-binding protein isoform 2 [Homo sapiens]","2//1;5"]
[114659,3191,3.9,3.65,-0.0955776599822311,0.613800615255658,"*",0.45841,"LRRC37B","GO:0016021//integral component of membrane","NA","NA","K20636//Rho GTPase-activating protein 12/27;K06839//slit 2;K10874//RAD52 motif-containing protein 1","BAG63955.1//unnamed protein product [Homo sapiens]","1//3;2//1"]
[25960,6050,1.25,1.17,-0.0954195650786826,0.768760500645902,"*",0.670584,"ADGRA2","GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0030175//filopodium","GO:0004930//G-protein coupled receptor activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0045765//regulation of angiogenesis;GO:1900747//negative regulation of vascular endothelial growth factor signaling pathway;GO:0043542//endothelial cell migration;GO:0090210//regulation of establishment of blood-brain barrier;GO:0050920//regulation of chemotaxis;GO:0010595//positive regulation of endothelial cell migration;GO:0007166//cell surface receptor signaling pathway;GO:0007417//central nervous system development;GO:0002040//sprouting angiogenesis","K08461//G protein-coupled receptor 124","NP_116166.9//adhesion G protein-coupled receptor A2 precursor [Homo sapiens]","9//1"]
[2204,2302,6.2,5.81,-0.0937300518697086,0.684435335602451,"*",0.566478,"FCAR","GO:0005887//integral component of plasma membrane;GO:0101003//ficolin-1-rich granule membrane;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane;GO:0005576//extracellular region;GO:0070821//tertiary granule membrane;GO:0005886//plasma membrane","GO:0019766//IgA receptor activity;GO:0019862//IgA binding","GO:0042119//neutrophil activation;GO:0071222//cellular response to lipopolysaccharide;GO:0071356//cellular response to tumor necrosis factor;GO:0033031//positive regulation of neutrophil apoptotic process;GO:0002446//neutrophil mediated immunity;GO:0071346//cellular response to interferon-gamma;GO:0071354//cellular response to interleukin-6;GO:0043312//neutrophil degranulation;GO:0038093//Fc receptor signaling pathway;GO:0006955//immune response;GO:1903209//positive regulation of oxidative stress-induced cell death;GO:0035457//cellular response to interferon-alpha;GO:0097011//cellular response to granulocyte macrophage colony-stimulating factor stimulus","K06513//CD89 antigen","NP_579807.1//immunoglobulin alpha Fc receptor isoform e [Homo sapiens];NP_579808.1//immunoglobulin alpha Fc receptor isoform f [Homo sapiens];NP_579806.1//immunoglobulin alpha Fc receptor isoform d [Homo sapiens];NP_579812.1//immunoglobulin alpha Fc receptor isoform h [Homo sapiens];NP_579803.1//immunoglobulin alpha Fc receptor isoform b precursor [Homo sapiens];NP_001991.1//immunoglobulin alpha Fc receptor isoform a precursor [Homo sapiens];NP_579805.1//immunoglobulin alpha Fc receptor isoform c precursor [Homo sapiens];NP_579811.1//immunoglobulin alpha Fc receptor isoform g [Homo sapiens]","3//A2MP1"]
[84294,3693,7.01,6.57,-0.0935210736882935,0.574186337926283,"*",0.417394,"UTP23","GO:0032040//small-subunit processome;GO:0005730//nucleolus","GO:0003723//RNA binding;GO:0070181//small ribosomal subunit rRNA binding;GO:0048027//mRNA 5'-UTR binding;GO:0003730//mRNA 3'-UTR binding","GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000480//endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)","K14773//U3 small nucleolar RNA-associated protein 23","NP_115710.2//rRNA-processing protein UTP23 homolog [Homo sapiens]","2//1"]
[6490,1973,0.32,0.3,-0.0931094043914815,0.873721910496339,"*",0.806664,"PMEL","GO:0032585//multivesicular body membrane;GO:0042470//melanosome;GO:0005887//integral component of plasma membrane;GO:0005794//Golgi apparatus;GO:0005576//extracellular region;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane","GO:0042802//identical protein binding","GO:0042438//melanin biosynthetic process;GO:0048066//developmental pigmentation;GO:0032438//melanosome organization","K17304//melanocyte protein PMEL","NP_008859.1//melanocyte protein PMEL isoform 3 preproprotein [Homo sapiens];NP_001307051.1//melanocyte protein PMEL isoform 5 preproprotein [Homo sapiens];NP_001186982.1//melanocyte protein PMEL isoform 2 precursor [Homo sapiens];NP_001307050.1//melanocyte protein PMEL isoform 4 preproprotein [Homo sapiens];NP_001186983.1//melanocyte protein PMEL isoform 1 preproprotein [Homo sapiens]","1//3;4"]
[54797,1833,15.26,14.31,-0.0927312901078626,0.637381012687619,"*",0.481168,"MED18","NA","NA","NA","K15135//mediator of RNA polymerase II transcription subunit 18","XP_009201399.1//mediator of RNA polymerase II transcription subunit 18 isoform X1 [Papio anubis];XP_011761389.1//PREDICTED: mediator of RNA polymerase II transcription subunit 18 isoform X2 [Macaca nemestrina]","1//3;2//1"]
[374354,6409,3.56,3.34,-0.0920291384923456,0.617044924442955,"*",0.461142,"NHLRC2","GO:0031093//platelet alpha granule lumen;GO:0005623//cell;GO:0005576//extracellular region","NA","GO:0002576//platelet degranulation;GO:0045454//cell redox homeostasis","K12581//CCR4-NOT transcription complex subunit 7/8;K11447//histone demethylase [EC:1.14.11.-]","XP_002756652.2//PREDICTED: NHL repeat-containing protein 2 isoform X1 [Callithrix jacchus]","3//A2MP1"]
[3234,2596,2.43,2.28,-0.0919224894410391,0.787026213916614,"*",0.696026,"HOXD8","GO:0005634//nucleus","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0009952//anterior/posterior pattern specification;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007275//multicellular organism development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0008595//anterior/posterior axis specification, embryo;GO:0048705//skeletal system morphogenesis","K09308//homeobox protein HoxB/C/D8","NP_062458.1//homeobox protein Hox-D8 isoform 1 [Homo sapiens];NP_001186675.1//homeobox protein Hox-D8 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[51283,3035,29.67,27.85,-0.091327599252873,0.218867339857242,"*",0.119011,"BFAR","GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0005887//integral component of plasma membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0089720//caspase binding;GO:0061630//ubiquitin protein ligase activity;GO:0046872//metal ion binding;GO:0030674//protein binding, bridging","GO:0070534//protein K63-linked ubiquitination;GO:0070936//protein K48-linked ubiquitination;GO:0043066//negative regulation of apoptotic process;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0006915//apoptotic process;GO:1903895//negative regulation of IRE1-mediated unfolded protein response;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0051865//protein autoubiquitination;GO:0000209//protein polyubiquitination","K15684//bifunctional apoptosis regulator","NP_057645.1//bifunctional apoptosis regulator isoform 1 [Homo sapiens];NP_001317429.1//bifunctional apoptosis regulator isoform 2 [Homo sapiens]","1//3;2//1"]
[8932,5175,13.63,12.8,-0.0906417519178472,0.308775103947508,"*",0.1826478,"MBD2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0043234//protein complex;GO:0005829//cytosol;GO:0000118//histone deacetylase complex;GO:0000792//heterochromatin;GO:0000790//nuclear chromatin","GO:0035197//siRNA binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003729//mRNA binding;GO:0003696//satellite DNA binding;GO:0008327//methyl-CpG binding;GO:0070742//C2H2 zinc finger domain binding;GO:0019904//protein domain specific binding;GO:0003682//chromatin binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0031492//nucleosomal DNA binding","GO:0042127//regulation of cell proliferation;GO:0035563//positive regulation of chromatin binding;GO:0048568//embryonic organ development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0032355//response to estradiol;GO:0071407//cellular response to organic cyclic compound;GO:0043044//ATP-dependent chromatin remodeling;GO:0000183//chromatin silencing at rDNA;GO:0044030//regulation of DNA methylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0009612//response to mechanical stimulus;GO:0007507//heart development;GO:0006351//transcription, DNA-templated;GO:0007568//aging;GO:0030177//positive regulation of Wnt signaling pathway;GO:0006346//methylation-dependent chromatin silencing;GO:0031667//response to nutrient levels;GO:0042711//maternal behavior;GO:0043623//cellular protein complex assembly","K11590//methyl-CpG-binding domain protein 2","NP_056647.1//methyl-CpG-binding domain protein 2 testis-specific isoform [Homo sapiens];NP_003918.1//methyl-CpG-binding domain protein 2 isoform 1 [Homo sapiens]",4]
[128239,6069,12.42,11.67,-0.0898606125131334,0.320785304956513,"*",0.1916398,"IQGAP3","GO:0005829//cytosol;GO:0005911//cell-cell junction;GO:0016328//lateral plasma membrane","GO:0017048//Rho GTPase binding;GO:0070856//myosin VI light chain binding;GO:0005516//calmodulin binding","GO:0000187//activation of MAPK activity;GO:0008361//regulation of cell size;GO:0010629//negative regulation of gene expression;GO:0010628//positive regulation of gene expression;GO:0070371//ERK1 and ERK2 cascade;GO:0071310//cellular response to organic substance;GO:0043087//regulation of GTPase activity;GO:0033601//positive regulation of mammary gland epithelial cell proliferation;GO:0000082//G1/S transition of mitotic cell cycle;GO:0007265//Ras protein signal transduction","K05767//Ras GTPase-activating-like protein IQGAP2/3","NP_839943.2//ras GTPase-activating-like protein IQGAP3 [Homo sapiens]",4]
[91833,2381,11.84,11.13,-0.0892154882869902,0.0238833717819843,"*",0.00916222,"WDR20","GO:0005654//nucleoplasm","GO:0036459//thiol-dependent ubiquitinyl hydrolase activity","GO:0016579//protein deubiquitination","K06100//symplekin;K04799//flap endonuclease-1 [EC:3.-.-.-]","AAH28387.1//WD repeat domain 20 [Homo sapiens];NP_851808.1//WD repeat-containing protein 20 isoform 1 [Homo sapiens];NP_001340587.1//WD repeat-containing protein 20 isoform 14 [Homo sapiens];NP_001229343.1//WD repeat-containing protein 20 isoform 4 [Homo sapiens];NP_851825.1//WD repeat-containing protein 20 isoform 3 [Homo sapiens];NP_001317157.1//WD repeat-containing protein 20 isoform 11 [Homo sapiens];NP_001340589.1//WD repeat-containing protein 20 isoform 16 [Homo sapiens];XP_014203186.1//PREDICTED: WD repeat-containing protein 20 isoform X5 [Pan paniscus];XP_018865436.1//PREDICTED: WD repeat-containing protein 20 isoform X2 [Gorilla gorilla gorilla];NP_653175.2//WD repeat-containing protein 20 isoform 2 [Homo sapiens];XP_007986076.1//PREDICTED: WD repeat-containing protein 20 isoform X3 [Chlorocebus sabaeus];NP_001307059.1//WD repeat-containing protein 20 isoform 10 [Homo sapiens];NP_001340586.1//WD repeat-containing protein 20 isoform 13 [Homo sapiens];NP_001229344.1//WD repeat-containing protein 20 isoform 5 [Homo sapiens];NP_001340608.1//WD repeat-containing protein 20 isoform 23 [Homo sapiens];NP_001340588.1//WD repeat-containing protein 20 isoform 15 [Homo sapiens];BAG52255.1//unnamed protein product [Homo sapiens];NP_001229345.1//WD repeat-containing protein 20 isoform 6 [Homo sapiens];NP_001229347.1//WD repeat-containing protein 20 isoform 8 [Homo sapiens];NP_001340590.1//WD repeat-containing protein 20 isoform 17 [Homo sapiens];XP_011535639.1//PREDICTED: WD repeat-containing protein 20 isoform X3 [Homo sapiens];NP_001229346.1//WD repeat-containing protein 20 isoform 7 [Homo sapiens];NP_001340585.1//WD repeat-containing protein 20 isoform 12 [Homo sapiens];NP_001340609.1//WD repeat-containing protein 20 isoform 24 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[158586,5651,3.18,2.99,-0.0888812810862503,0.639399334363412,"*",0.518116,"ZXDB","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K20828//zinc finger protein 143/76;K10485//BTB/POZ domain-containing protein 13 (germ cell-less protein-like 1)","XP_011829054.1//PREDICTED: zinc finger X-linked protein ZXDB [Mandrillus leucophaeus]","3//A2MP1"]
[223,2500,18.31,17.22,-0.0885466484004931,0.474904130039489,"*",0.323728,"ALDH9A1","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0004028//3-chloroallyl aldehyde dehydrogenase activity;GO:0033737//1-pyrroline dehydrogenase activity;GO:0047105//4-trimethylammoniobutyraldehyde dehydrogenase activity;GO:0016491//oxidoreductase activity;GO:0019145//aminobutyraldehyde dehydrogenase activity;GO:0004029//aldehyde dehydrogenase (NAD) activity","GO:0042136//neurotransmitter biosynthetic process;GO:0006081//cellular aldehyde metabolic process;GO:0042445//hormone metabolic process;GO:0045329//carnitine biosynthetic process;GO:0055114//oxidation-reduction process","K00149//aldehyde dehydrogenase family 9 member A1 [EC:1.2.1.47 1.2.1.3]","NP_000687.3//4-trimethylaminobutyraldehyde dehydrogenase [Homo sapiens]","3//A2MP1"]
[7360,2153,35.89,33.77,-0.0878397438086007,0.34564743552713,"*",0.20976,"UGP2","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0032557//pyrimidine ribonucleotide binding;GO:0042802//identical protein binding;GO:0003983//UTP:glucose-1-phosphate uridylyltransferase activity;GO:0005536//glucose binding","GO:0005977//glycogen metabolic process;GO:0005978//glycogen biosynthetic process;GO:0006011//UDP-glucose metabolic process;GO:0006065//UDP-glucuronate biosynthetic process;GO:0019255//glucose 1-phosphate metabolic process","K00963//UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]","NP_006750.3//UTP--glucose-1-phosphate uridylyltransferase isoform a [Homo sapiens];XP_012877992.1//PREDICTED: UTP--glucose-1-phosphate uridylyltransferase isoform X1 [Dipodomys ordii]","1//3;3//A2MP1"]
[54596,4005,0.51,0.48,-0.0874628412503394,0.940935285629493,"*",0.893164,"L1TD1","GO:0030529//intracellular ribonucleoprotein complex","GO:0003727//single-stranded RNA binding","GO:0032197//transposition, RNA-mediated","K19475//WAS/WASL-interacting protein;K19607//X-linked retinitis pigmentosa GTPase regulator;K18626//trichohyalin","NP_061952.3//LINE-1 type transposase domain-containing protein 1 [Homo sapiens]","4;1//3"]
[4678,2562,31.83,29.96,-0.0873495331771698,0.0174310281702561,"*",0.00643488,"NASP","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0043234//protein complex;GO:0000790//nuclear chromatin;GO:0005737//cytoplasm","GO:0042393//histone binding;GO:0051879//Hsp90 protein binding;GO:0032403//protein complex binding","GO:0006260//DNA replication;GO:0006334//nucleosome assembly;GO:0043486//histone exchange;GO:0008584//male gonad development;GO:0006335//DNA replication-dependent nucleosome assembly;GO:0001824//blastocyst development;GO:0033574//response to testosterone;GO:0008283//cell proliferation;GO:0006336//DNA replication-independent nucleosome assembly;GO:0015031//protein transport;GO:0007049//cell cycle","K11291//nuclear autoantigenic sperm protein","NP_001182122.1//nuclear autoantigenic sperm protein isoform 4 [Homo sapiens];NP_689511.2//nuclear autoantigenic sperm protein isoform 3 [Homo sapiens];NP_002473.2//nuclear autoantigenic sperm protein isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[122622,1796,3.08,2.9,-0.086877450679967,0.818887972743707,"*",0.737276,"ADSSL1","GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0000287//magnesium ion binding;GO:0051015//actin filament binding;GO:0042803//protein homodimerization activity;GO:0003924//GTPase activity;GO:0046872//metal ion binding;GO:0042301//phosphate ion binding;GO:0005525//GTP binding;GO:0004019//adenylosuccinate synthase activity","GO:0071257//cellular response to electrical stimulus;GO:0035690//cellular response to drug;GO:0006531//aspartate metabolic process;GO:0044208//'de novo' AMP biosynthetic process;GO:0006167//AMP biosynthetic process;GO:0006541//glutamine metabolic process;GO:0014850//response to muscle activity;GO:0042594//response to starvation;GO:0002376//immune system process;GO:0046040//IMP metabolic process;GO:0009168//purine ribonucleoside monophosphate biosynthetic process","K01939//adenylosuccinate synthase [EC:6.3.4.4]","CAD62614.1//unnamed protein product, partial [Homo sapiens];XP_007986184.1//PREDICTED: adenylosuccinate synthetase isozyme 1 isoform X2 [Chlorocebus sabaeus];XP_007942776.1//PREDICTED: adenylosuccinate synthetase isozyme 1 isoform X1 [Orycteropus afer afer]","4;1//3;2//1"]
[340156,5865,0.86,0.81,-0.086414751817473,0.811851509513151,"*",0.72657,"MYLK4","GO:0070062//extracellular exosome;GO:0005622//intracellular","GO:0005524//ATP binding;GO:0004687//myosin light chain kinase activity","GO:0018107//peptidyl-threonine phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0035556//intracellular signal transduction","K00907//myosin-light-chain kinase [EC:2.7.11.18]","NP_001334801.1//myosin light chain kinase family member 4 isoform 2 [Homo sapiens];XP_007972049.1//PREDICTED: myosin light chain kinase family member 4 isoform X3 [Chlorocebus sabaeus]","4;1//3"]
[22880,5216,7.95,7.49,-0.0859891417129666,0.448672966598246,"*",0.301044,"MORC2","GO:0005634//nucleus;GO:0005829//cytosol","GO:0008270//zinc ion binding","GO:0006631//fatty acid metabolic process","K04574//neurofilament heavy polypeptide","NP_001290185.1//MORC family CW-type zinc finger protein 2 isoform 1 [Homo sapiens];NP_001290186.1//MORC family CW-type zinc finger protein 2 isoform 2 [Homo sapiens]","3//A2MP1;2//1"]
[190,1591,44.39,41.84,-0.0853518570781518,0.384285881083242,"*",0.240738,"NR0B1","GO:0016020//membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0042788//polysomal ribosome;GO:0005737//cytoplasm","GO:0003707//steroid hormone receptor activity;GO:0003723//RNA binding;GO:0003677//DNA binding;GO:0050682//AF-2 domain binding;GO:0003714//transcription corepressor activity;GO:0042803//protein homodimerization activity;GO:0004879//nuclear receptor activity;GO:0035258//steroid hormone receptor binding;GO:0032448//DNA hairpin binding;GO:0019904//protein domain specific binding;GO:0043565//sequence-specific DNA binding;GO:0008134//transcription factor binding","GO:0030238//male sex determination;GO:0043433//negative regulation of DNA binding transcription factor activity;GO:0021854//hypothalamus development;GO:0007283//spermatogenesis;GO:0008584//male gonad development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0008406//gonad development;GO:0060008//Sertoli cell differentiation;GO:0021983//pituitary gland development;GO:0033144//negative regulation of intracellular steroid hormone receptor signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006694//steroid biosynthetic process;GO:0006351//transcription, DNA-templated;GO:0035902//response to immobilization stress;GO:0033327//Leydig cell differentiation;GO:0030325//adrenal gland development;GO:0045596//negative regulation of cell differentiation;GO:0008104//protein localization;GO:0006367//transcription initiation from RNA polymerase II promoter","K08562//nuclear receptor subfamily 0 group B member 1","NP_000466.2//nuclear receptor subfamily 0 group B member 1 [Homo sapiens]",4]
[51805,1265,5.6,5.28,-0.0848888975865129,0.799631376100275,"*",0.710878,"COQ3","GO:0005759//mitochondrial matrix;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0044596//3-demethylubiquinone-10 3-O-methyltransferase activity;GO:0008425//2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity;GO:0008171//O-methyltransferase activity;GO:0004395//hexaprenyldihydroxybenzoate methyltransferase activity;GO:0044595//decaprenyldihydroxybenzoate methyltransferase activity;GO:0008689//3-demethylubiquinone-9 3-O-methyltransferase activity","GO:0006071//glycerol metabolic process;GO:0010795//regulation of ubiquinone biosynthetic process;GO:0006744//ubiquinone biosynthetic process","K00591//polyprenyldihydroxybenzoate methyltransferase / 3-demethylubiquinol 3-O-methyltransferase [EC:2.1.1.114 2.1.1.64]","NP_059117.3//ubiquinone biosynthesis O-methyltransferase, mitochondrial [Homo sapiens]","3//A2MP1"]
[58533,3337,35.6,33.58,-0.0842750109167302,0.228275330150867,"*",0.1269276,"SNX6","GO:0097422//tubular endosome;GO:0030904//retromer complex;GO:0005634//nucleus;GO:0019898//extrinsic component of membrane;GO:0005622//intracellular;GO:0005764//lysosome;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0031901//early endosome membrane;GO:0030905//retromer, tubulation complex;GO:0005829//cytosol","GO:0034452//dynactin binding;GO:0046982//protein heterodimerization activity;GO:0034713//type I transforming growth factor beta receptor binding;GO:0042803//protein homodimerization activity;GO:0035091//phosphatidylinositol binding","GO:0016241//regulation of macroautophagy;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006886//intracellular protein transport;GO:0016050//vesicle organization;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0042147//retrograde transport, endosome to Golgi;GO:0006897//endocytosis;GO:0007175//negative regulation of epidermal growth factor-activated receptor activity","K17920//sorting nexin-5/6/32","XP_011375534.1//PREDICTED: sorting nexin-6 [Pteropus vampyrus];XP_012901678.1//PREDICTED: sorting nexin-6 [Mustela putorius furo]","4;3//A2MP1"]
[153768,4970,2.66,2.51,-0.0837388815504177,0.731673943723575,"*",0.62834,"PRELID2","GO:0005758//mitochondrial intermembrane space;GO:0005739//mitochondrion","GO:1990050//phosphatidic acid transporter activity","NA","K11447//histone demethylase [EC:1.14.11.-];K15696//RING finger protein 113B","NP_995318.1//PRELI domain-containing protein 2 isoform b [Homo sapiens];NP_892005.1//PRELI domain-containing protein 2 isoform a [Homo sapiens]","3//A2MP1;2//1;5"]
[25987,2720,220.22,207.85,-0.083402749961556,0.000634660567381174,"*",1.705248E-4,"TSKU","GO:0005615//extracellular space;GO:0005886//plasma membrane","GO:0004930//G-protein coupled receptor activity","GO:0021540//corpus callosum morphogenesis;GO:0010468//regulation of gene expression;GO:0030178//negative regulation of Wnt signaling pathway;GO:0021670//lateral ventricle development;GO:0021960//anterior commissure morphogenesis;GO:0061073//ciliary body morphogenesis;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway","K08130//tsukushi (leucine-rich repeat-containing protein 54)","XP_021560357.1//tsukushin [Neomonachus schauinslandi];NP_001305406.1//tsukushin isoform a precursor [Homo sapiens];XP_003254731.1//PREDICTED: tsukushin isoform X1 [Nomascus leucogenys]","1//3;3//A2MP1"]
[29907,1768,27.38,25.85,-0.0829581660556025,0.414786648318043,"*",0.271712,"SNX15","GO:0016020//membrane;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0030659//cytoplasmic vesicle membrane","GO:0035091//phosphatidylinositol binding","GO:0006886//intracellular protein transport;GO:0007165//signal transduction","K17927//sorting nexin-15","EAW74337.1//hCG23393, isoform CRA_b [Homo sapiens];EAW74336.1//hCG23393, isoform CRA_a [Homo sapiens]","4;3//A2MP1"]
[147949,2590,0.72,0.68,-0.0824621601919728,0.937695230982751,"*",0.88821,"ZNF583","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_012415365.1//PREDICTED: zinc finger protein 850 isoform X1 [Trichechus manatus latirostris]","1//3;2//1"]
[1717,2652,79.95,75.53,-0.0820482468220734,0.0936443087197513,"*",0.0433634,"DHCR7","GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005640//nuclear outer membrane","GO:0050661//NADP binding;GO:0047598//7-dehydrocholesterol reductase activity;GO:0009918//sterol delta7 reductase activity","GO:0030324//lung development;GO:0033489//cholesterol biosynthetic process via desmosterol;GO:0030154//cell differentiation;GO:0016132//brassinosteroid biosynthetic process;GO:0042127//regulation of cell proliferation;GO:0006695//cholesterol biosynthetic process;GO:0001568//blood vessel development;GO:0045540//regulation of cholesterol biosynthetic process;GO:0035264//multicellular organism growth;GO:0033490//cholesterol biosynthetic process via lathosterol;GO:0009791//post-embryonic development","K00213//7-dehydrocholesterol reductase [EC:1.3.1.21]","NP_001351.2//7-dehydrocholesterol reductase [Homo sapiens]","1//3;2//1"]
[9688,2922,27.4,25.89,-0.0817809279477777,0.370243683743445,"*",0.229832,"NUP93","GO:0016020//membrane;GO:0043657//host cell;GO:0005643//nuclear pore;GO:0031965//nuclear membrane;GO:0034399//nuclear periphery;GO:0005635//nuclear envelope","GO:0017056//structural constituent of nuclear pore","GO:0006406//mRNA export from nucleus;GO:0007077//mitotic nuclear envelope disassembly;GO:0016925//protein sumoylation;GO:0006110//regulation of glycolytic process;GO:0051028//mRNA transport;GO:0016973//poly(A)+ mRNA export from nucleus;GO:0072001//renal system development;GO:0015031//protein transport;GO:0090521//glomerular visceral epithelial cell migration;GO:0006998//nuclear envelope organization;GO:0051292//nuclear pore complex assembly;GO:0060391//positive regulation of SMAD protein import into nucleus;GO:0060964//regulation of gene silencing by miRNA;GO:0006409//tRNA export from nucleus;GO:0016032//viral process;GO:0060395//SMAD protein signal transduction;GO:1903206//negative regulation of hydrogen peroxide-induced cell death;GO:1900034//regulation of cellular response to heat;GO:0072015//glomerular visceral epithelial cell development;GO:0006606//protein import into nucleus;GO:0019083//viral transcription;GO:0075733//intracellular transport of virus","K14309//nuclear pore complex protein Nup93","NP_055484.3//nuclear pore complex protein Nup93 isoform 1 [Homo sapiens];XP_005977697.1//PREDICTED: nuclear pore complex protein Nup93 isoform X3 [Pantholops hodgsonii]","4;1//3;2//1"]
[5095,2531,3.85,3.64,-0.0809199953835675,0.759127025149528,"*",0.659472,"PCCA","GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0005739//mitochondrion","GO:0046872//metal ion binding;GO:0004075//biotin carboxylase activity;GO:0004658//propionyl-CoA carboxylase activity;GO:0005524//ATP binding;GO:0009374//biotin binding;GO:0019899//enzyme binding","GO:0019626//short-chain fatty acid catabolic process;GO:0006768//biotin metabolic process","K01965//propionyl-CoA carboxylase alpha chain [EC:6.4.1.3]","NP_001339538.1//propionyl-CoA carboxylase alpha chain, mitochondrial isoform h precursor [Homo sapiens];NP_000273.2//propionyl-CoA carboxylase alpha chain, mitochondrial isoform a precursor [Homo sapiens];NP_001171475.1//propionyl-CoA carboxylase alpha chain, mitochondrial isoform c precursor [Homo sapiens];CAA32763.1//propionyl-CoA carboxylase [Homo sapiens];NP_001339536.1//propionyl-CoA carboxylase alpha chain, mitochondrial isoform f [Homo sapiens];NP_001121164.1//propionyl-CoA carboxylase alpha chain, mitochondrial isoform b [Homo sapiens];NP_001339537.1//propionyl-CoA carboxylase alpha chain, mitochondrial isoform g [Homo sapiens];NP_001339534.1//propionyl-CoA carboxylase alpha chain, mitochondrial isoform d precursor [Homo sapiens];NP_001339535.1//propionyl-CoA carboxylase alpha chain, mitochondrial isoform e precursor [Homo sapiens]","1//3;3//A2MP1;2//1"]
[727957,4544,6.26,5.92,-0.0805654813036684,0.346850828282828,"*",0.210664,"MROH1","NA","NA","NA","K16628//collagen, type VII, alpha","XP_011515576.1//PREDICTED: maestro heat-like repeat-containing protein family member 1 isoform X6 [Homo sapiens];AAH92486.1//HEATR7A protein, partial [Homo sapiens];AAH57824.1//HEATR7A protein, partial [Homo sapiens];XP_011515575.1//PREDICTED: maestro heat-like repeat-containing protein family member 1 isoform X5 [Homo sapiens]","1//3;2//1"]
[121551,4198,9.63,9.11,-0.0800847440414089,0.00428636714004721,"*",1.36421E-3,"BTBD11","GO:0016021//integral component of membrane;GO:0005737//cytoplasm;GO:0019005//SCF ubiquitin ligase complex","GO:0031625//ubiquitin protein ligase binding;GO:0046982//protein heterodimerization activity","GO:0060395//SMAD protein signal transduction;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0030162//regulation of proteolysis;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process","K10483//BTB/POZ domain-containing protein 11","NP_001334872.1//ankyrin repeat and BTB/POZ domain-containing protein BTBD11 isoform c [Homo sapiens];NP_001334873.1//ankyrin repeat and BTB/POZ domain-containing protein BTBD11 isoform d [Homo sapiens];NP_001017523.1//ankyrin repeat and BTB/POZ domain-containing protein BTBD11 isoform b [Homo sapiens];NP_001018082.1//ankyrin repeat and BTB/POZ domain-containing protein BTBD11 isoform a [Homo sapiens]","1//3"]
[51661,2901,2.61,2.47,-0.0795387649852068,0.811422258087152,"*",0.7239,"FKBP7","NA","GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005509//calcium ion binding","NA","K09573//FK506-binding protein 7 [EC:5.2.1.8]","EAX11032.1//FK506 binding protein 7, isoform CRA_e [Homo sapiens]","1//3;2//1"]
[26585,3928,5.82,5.51,-0.0789668343371263,0.630974995585908,"*",0.474278,"GREM1","GO:0005615//extracellular space;GO:0009986//cell surface","GO:0030297//transmembrane receptor protein tyrosine kinase activator activity;GO:0005125//cytokine activity;GO:0048018//receptor ligand activity;GO:0043184//vascular endothelial growth factor receptor 2 binding;GO:0042803//protein homodimerization activity;GO:0036122//BMP binding;GO:0016015//morphogen activity","GO:2000273//positive regulation of receptor activity;GO:0010717//regulation of epithelial to mesenchymal transition;GO:0003257//positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation;GO:0030199//collagen fibril organization;GO:0051973//positive regulation of telomerase activity;GO:0002092//positive regulation of receptor internalization;GO:0090291//negative regulation of osteoclast proliferation;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0051893//regulation of focal adhesion assembly;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0045668//negative regulation of osteoblast differentiation;GO:1900158//negative regulation of bone mineralization involved in bone maturation;GO:0045766//positive regulation of angiogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0090191//negative regulation of branching involved in ureteric bud morphogenesis;GO:0007165//signal transduction;GO:0043066//negative regulation of apoptotic process;GO:0006915//apoptotic process;GO:0090190//positive regulation of branching involved in ureteric bud morphogenesis;GO:0060173//limb development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0009954//proximal/distal pattern formation;GO:2000727//positive regulation of cardiac muscle cell differentiation;GO:0060394//negative regulation of pathway-restricted SMAD protein phosphorylation;GO:0030514//negative regulation of BMP signaling pathway;GO:1900086//positive regulation of peptidyl-tyrosine autophosphorylation;GO:0030502//negative regulation of bone mineralization;GO:1900155//negative regulation of bone trabecula formation;GO:0002042//cell migration involved in sprouting angiogenesis;GO:0046851//negative regulation of bone remodeling;GO:0090027//negative regulation of monocyte chemotaxis;GO:0003337//mesenchymal to epithelial transition involved in metanephros morphogenesis;GO:0000902//cell morphogenesis;GO:0030308//negative regulation of cell growth;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0007267//cell-cell signaling;GO:0030326//embryonic limb morphogenesis;GO:0042346//positive regulation of NF-kappaB import into nucleus;GO:0033689//negative regulation of osteoblast proliferation;GO:0060676//ureteric bud formation;GO:0048263//determination of dorsal identity;GO:0032331//negative regulation of chondrocyte differentiation;GO:0008284//positive regulation of cell proliferation","K19558//neuroblastoma suppressor of tumorigenicity 1;K01645//cerberus 1","XP_003805004.1//PREDICTED: gremlin-1 [Pan paniscus];XP_022348550.1//gremlin-1 isoform X2 [Enhydra lutris kenyoni];XP_022348551.1//gremlin-1 isoform X3 [Enhydra lutris kenyoni]","6;1//3"]
[55502,1455,4.91,4.65,-0.0784923083192993,0.802847485223755,"*",0.71429,"HES6","GO:0005634//nucleus;GO:0005667//transcription factor complex","GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003712//transcription cofactor activity;GO:0008134//transcription factor binding;GO:0003700//DNA binding transcription factor activity;GO:0001227//transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0046983//protein dimerization activity","GO:0007399//nervous system development;GO:0030154//cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09087//hairy and enhancer of split 2/6/7","XP_011898349.1//PREDICTED: transcription cofactor HES-6 isoform X1 [Cercocebus atys];XP_005574844.1//PREDICTED: transcription cofactor HES-6 isoform X1 [Macaca fascicularis]","1//3;2//1;5"]
[9519,1338,13.7,12.98,-0.0778855098487504,0.669114453686776,"*",0.549902,"TBPL1","NA","NA","NA","K03120//transcription initiation factor TFIID TATA-box-binding protein","XP_006144394.1//PREDICTED: TATA box-binding protein-like protein 1 isoform X1 [Tupaia chinensis];XP_014706054.1//PREDICTED: TATA box-binding protein-like protein 1 isoform X2 [Equus asinus]","1//3;3//A2MP1"]
[23070,4137,8.81,8.35,-0.0773658215589991,0.596717132037021,"*",0.439936,"CMTR1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol","GO:0004483//mRNA (nucleoside-2'-O-)-methyltransferase activity;GO:0003676//nucleic acid binding","GO:0006370//7-methylguanosine mRNA capping;GO:0097309//cap1 mRNA methylation;GO:0080009//mRNA methylation","K14589//cap1 methyltransferase [EC:2.1.1.57]","NP_055865.1//cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 [Homo sapiens]","2//1"]
[125061,1760,20.67,19.6,-0.0766847344228769,0.591455469822082,"*",0.434946,"AFMID","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0016787//hydrolase activity;GO:0004061//arylformamidase activity","GO:0034354//'de novo' NAD biosynthetic process from tryptophan;GO:0019441//tryptophan catabolic process to kynurenine","K01432//arylformamidase [EC:3.5.1.9]","NP_001138998.1//kynurenine formamidase isoform 1 [Homo sapiens];NP_001010982.2//kynurenine formamidase isoform 2 [Homo sapiens]","4;2//1"]
[53340,955,11.93,11.32,-0.0757200848633457,0.778964992418824,"*",0.681826,"SPA17","GO:0016020//membrane;GO:0005929//cilium;GO:0009897//external side of plasma membrane;GO:0031514//motile cilium;GO:0097228//sperm principal piece;GO:0005737//cytoplasm;GO:0035686//sperm fibrous sheath","NA","GO:0007338//single fertilization;GO:0007283//spermatogenesis;GO:0003351//epithelial cilium movement;GO:0007339//binding of sperm to zona pellucida","K05970//sialate O-acetylesterase [EC:3.1.1.53];K20041//neuromodulin","NP_059121.1//sperm surface protein Sp17 [Homo sapiens]","3//A2MP1"]
[9489,2343,13.59,12.9,-0.0751743904567747,0.646436349248307,"*",0.489906,"PGS1","GO:0005783//endoplasmic reticulum;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0005524//ATP binding;GO:0005509//calcium ion binding;GO:0008444//CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity;GO:0017169//CDP-alcohol phosphatidyltransferase activity","GO:0032049//cardiolipin biosynthetic process;GO:0006655//phosphatidylglycerol biosynthetic process;GO:0046339//diacylglycerol metabolic process","K00995//CDP-diacylglycerol---glycerol-3-phosphate 3-phosphatidyltransferase [EC:2.7.8.5]","NP_077733.3//CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial precursor [Homo sapiens]",4]
[23107,2777,34.84,33.08,-0.0747853894275901,0.365900198544278,"*",0.226586,"MRPS27","GO:0005840//ribosome;GO:0005763//mitochondrial small ribosomal subunit;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0005737//cytoplasm","GO:0097177//mitochondrial ribosome binding;GO:0000049//tRNA binding;GO:0019843//rRNA binding","GO:0008283//cell proliferation;GO:0070131//positive regulation of mitochondrial translation;GO:0070126//mitochondrial translational termination;GO:0070125//mitochondrial translational elongation","K17406//small subunit ribosomal protein S27","NP_001273677.1//28S ribosomal protein S27, mitochondrial isoform 1 [Homo sapiens];NP_055899.2//28S ribosomal protein S27, mitochondrial isoform 2 [Homo sapiens]","1//3;2//1"]
[8330,460,0.2,0.19,-0.0740005814437769,1.00986424514087,"*",0.998548,"HIST1H2AK","NA","NA","NA","K11251//histone H2A","XP_019687248.1//PREDICTED: histone H2A type 1-E isoform X1 [Felis catus]","2//1"]
[2822,5858,1.4,1.33,-0.0740005814437767,0.817364673763306,"*",0.735444,"GPLD1","GO:0005765//lysosomal membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005622//intracellular;GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005578//proteinaceous extracellular matrix","GO:0004630//phospholipase D activity;GO:0017080//sodium channel regulator activity;GO:0004621//glycosylphosphatidylinositol phospholipase D activity","GO:0010867//positive regulation of triglyceride biosynthetic process;GO:0046470//phosphatidylcholine metabolic process;GO:0006501//C-terminal protein lipidation;GO:0008286//insulin receptor signaling pathway;GO:0035690//cellular response to drug;GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0010595//positive regulation of endothelial cell migration;GO:0010897//negative regulation of triglyceride catabolic process;GO:0071467//cellular response to pH;GO:0001503//ossification;GO:0097241//hematopoietic stem cell migration to bone marrow;GO:0010983//positive regulation of high-density lipoprotein particle clearance;GO:0035701//hematopoietic stem cell migration;GO:0043065//positive regulation of apoptotic process;GO:0002042//cell migration involved in sprouting angiogenesis;GO:0071277//cellular response to calcium ion;GO:1900076//regulation of cellular response to insulin stimulus;GO:0009749//response to glucose;GO:0008285//negative regulation of cell proliferation;GO:0010907//positive regulation of glucose metabolic process;GO:0045919//positive regulation of cytolysis;GO:0051044//positive regulation of membrane protein ectodomain proteolysis;GO:0070633//transepithelial transport;GO:0032869//cellular response to insulin stimulus;GO:0071397//cellular response to cholesterol;GO:0002062//chondrocyte differentiation;GO:0002430//complement receptor mediated signaling pathway;GO:0010694//positive regulation of alkaline phosphatase activity;GO:0071401//cellular response to triglyceride;GO:0006507//GPI anchor release;GO:0051047//positive regulation of secretion","K01127//glycosylphosphatidylinositol phospholipase D [EC:3.1.4.50]","NP_001494.2//phosphatidylinositol-glycan-specific phospholipase D precursor [Homo sapiens]","3//A2MP1"]
[112495,957,31.31,29.75,-0.0737338400560016,0.637012825121819,"*",0.515584,"GTF3C6","GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0000127//transcription factor TFIIIC complex","GO:0003677//DNA binding","GO:0042791//5S class rRNA transcription from RNA polymerase III type 1 promoter;GO:0042797//tRNA transcription from RNA polymerase III promoter;GO:0006351//transcription, DNA-templated;GO:0006383//transcription from RNA polymerase III promoter","K15203//general transcription factor 3C polypeptide 6","NP_612417.1//general transcription factor 3C polypeptide 6 [Homo sapiens]","3//A2MP1"]
[10884,1686,18.42,17.51,-0.0730939776577778,0.628716331853237,"*",0.505248,"MRPS30","GO:0005840//ribosome;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome","GO:0006412//translation;GO:0070126//mitochondrial translational termination;GO:0070125//mitochondrial translational elongation;GO:0006915//apoptotic process","K17409//small subunit ribosomal protein S30","NP_057724.2//39S ribosomal protein S30, mitochondrial [Homo sapiens]","3//A2MP1"]
[2720,2694,29.01,27.58,-0.0729278386840172,0.0653430376803314,"*",0.0286382,"GLB1","GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0005737//cytoplasm;GO:0005773//vacuole;GO:0048471//perinuclear region of cytoplasm;GO:0035578//azurophil granule lumen;GO:0005794//Golgi apparatus;GO:0005576//extracellular region;GO:1904813//ficolin-1-rich granule lumen;GO:0043202//lysosomal lumen","GO:0004308//exo-alpha-sialidase activity;GO:0004565//beta-galactosidase activity;GO:0016936//galactoside binding","GO:1904016//response to Thyroglobulin triiodothyronine;GO:0044262//cellular carbohydrate metabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0019388//galactose catabolic process;GO:0042340//keratan sulfate catabolic process;GO:0005975//carbohydrate metabolic process;GO:0043312//neutrophil degranulation;GO:0006027//glycosaminoglycan catabolic process;GO:0051413//response to cortisone","K12309//beta-galactosidase [EC:3.2.1.23]","NP_001129074.1//beta-galactosidase isoform c precursor [Homo sapiens];NP_000395.2//beta-galactosidase isoform a preproprotein [Homo sapiens];NP_001303969.1//beta-galactosidase isoform d precursor [Homo sapiens]","1//3;3//A2MP1;2//1"]
[64220,2772,22.43,21.33,-0.072545654745701,0.494583131256245,"*",0.340858,"STRA6","GO:0005887//integral component of plasma membrane;GO:0043234//protein complex;GO:0005886//plasma membrane","GO:0004872//receptor activity;GO:0034632//retinol transmembrane transporter activity","GO:0030540//female genitalia development;GO:0060539//diaphragm development;GO:0043010//camera-type eye development;GO:0001568//blood vessel development;GO:0048520//positive regulation of behavior;GO:0060900//embryonic camera-type eye formation;GO:0034633//retinol transport;GO:0003281//ventricular septum development;GO:0061038//uterus morphogenesis;GO:0007507//heart development;GO:0060323//head morphogenesis;GO:0050890//cognition;GO:0001523//retinoid metabolic process;GO:0043585//nose morphogenesis;GO:0060322//head development;GO:0030325//adrenal gland development;GO:0007631//feeding behavior;GO:0048566//embryonic digestive tract development;GO:0061205//paramesonephric duct development;GO:0030324//lung development;GO:0001822//kidney development;GO:0048745//smooth muscle tissue development;GO:0048546//digestive tract morphogenesis;GO:0061156//pulmonary artery morphogenesis;GO:0003184//pulmonary valve morphogenesis;GO:0097070//ductus arteriosus closure;GO:0043583//ear development;GO:0061143//alveolar primary septum development;GO:0061029//eyelid development in camera-type eye;GO:0060426//lung vasculature development;GO:0007612//learning;GO:0042297//vocal learning;GO:0048844//artery morphogenesis;GO:0048589//developmental growth;GO:0060325//face morphogenesis;GO:0048286//lung alveolus development;GO:0050905//neuromuscular process","K06236//collagen, type I, alpha;K19720//collagen, type III, alpha","BAH13848.1//unnamed protein product [Homo sapiens];NP_001136092.1//stimulated by retinoic acid gene 6 protein homolog isoform c [Homo sapiens];CAD97655.1//hypothetical protein, partial [Homo sapiens];NP_001185969.1//stimulated by retinoic acid gene 6 protein homolog isoform d [Homo sapiens]","1//3;3//A2MP1"]
[6591,2112,1.44,1.37,-0.0718929184817856,0.887308540307361,"*",0.824096,"SNAI2","NA","NA","NA","K05706//snail 2","XP_004679945.1//PREDICTED: zinc finger protein SNAI2 [Condylura cristata]",4]
[65988,3529,3.94,3.75,-0.071305034073133,0.683196993871529,"*",0.565282,"ZNF747","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_004057554.2//PREDICTED: zinc finger protein 768 isoform X3 [Gorilla gorilla gorilla];XP_018868176.1//PREDICTED: zinc finger protein 768 isoform X2 [Gorilla gorilla gorilla];XP_010339158.1//PREDICTED: zinc finger protein 768 [Saimiri boliviensis boliviensis]","1//3;3//A2MP1"]
[7818,2075,46.55,44.33,-0.0704978052808913,0.444527706559371,"*",0.2974,"DAP3","GO:0005654//nucleoplasm;GO:0005761//mitochondrial ribosome;GO:0005763//mitochondrial small ribosomal subunit;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0015935//small ribosomal subunit","GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005525//GTP binding","GO:0097190//apoptotic signaling pathway;GO:0070126//mitochondrial translational termination;GO:0006915//apoptotic process;GO:0070125//mitochondrial translational elongation","K17408//small subunit ribosomal protein S29","NP_001186780.1//28S ribosomal protein S29, mitochondrial isoform 3 [Homo sapiens];NP_004623.1//28S ribosomal protein S29, mitochondrial isoform 1 [Homo sapiens];NP_001186779.1//28S ribosomal protein S29, mitochondrial isoform 2 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[124512,1002,31.63,30.13,-0.0700928829229304,0.642471901736973,"*",0.486258,"METTL23","GO:0005634//nucleus;GO:0043234//protein complex;GO:0016021//integral component of membrane;GO:0005737//cytoplasm","GO:0008168//methyltransferase activity;GO:0031072//heat shock protein binding;GO:0008134//transcription factor binding","GO:0050890//cognition;GO:0045944//positive regulation of transcription from RNA polymerase II promoter","K21804//protein N-lysine methyltransferase METTL21A [EC:2.1.1.-];K00884//N-acetylglucosamine kinase [EC:2.7.1.59];K11323//histone arginine demethylase JMJD6 [EC:1.14.11.-];K21806//protein N-lysine methyltransferase METTL21D [EC:2.1.1.-]","XP_011897729.1//PREDICTED: methyltransferase-like protein 23 isoform X3 [Cercocebus atys];AAH33998.2//C17orf95 protein, partial [Homo sapiens];XP_016788457.1//PREDICTED: methyltransferase-like protein 23 isoform X1 [Pan troglodytes];XP_016879635.1//PREDICTED: methyltransferase-like protein 23 isoform X2 [Homo sapiens];XP_016788459.1//PREDICTED: methyltransferase-like protein 23 isoform X2 [Pan troglodytes]","4;1//3;2//1"]
[6118,1664,29.75,28.35,-0.0695409332530769,0.509289381765869,"*",0.354596,"RPA2","GO:0035861//site of double-strand break;GO:0016605//PML body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000784//nuclear chromosome, telomeric region;GO:0016604//nuclear body;GO:0000785//chromatin;GO:0005662//DNA replication factor A complex","GO:0003697//single-stranded DNA binding;GO:0003684//damaged DNA binding;GO:0047485//protein N-terminus binding;GO:0031625//ubiquitin protein ligase binding;GO:0019903//protein phosphatase binding;GO:0098505//G-rich strand telomeric DNA binding;GO:0019899//enzyme binding","GO:0034502//protein localization to chromosome;GO:0031571//mitotic G1 DNA damage checkpoint;GO:0006284//base-excision repair;GO:0006260//DNA replication;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0006296//nucleotide-excision repair, DNA incision, 5'-to lesion;GO:0006295//nucleotide-excision repair, DNA incision, 3'-to lesion;GO:0010569//regulation of double-strand break repair via homologous recombination;GO:0006289//nucleotide-excision repair;GO:0042769//DNA damage response, detection of DNA damage;GO:0036297//interstrand cross-link repair;GO:0006293//nucleotide-excision repair, preincision complex stabilization;GO:0033683//nucleotide-excision repair, DNA incision;GO:0006298//mismatch repair;GO:2000001//regulation of DNA damage checkpoint;GO:1901796//regulation of signal transduction by p53 class mediator;GO:0006294//nucleotide-excision repair, preincision complex assembly;GO:0019985//translesion synthesis;GO:1900034//regulation of cellular response to heat;GO:0042276//error-prone translesion synthesis;GO:0070987//error-free translesion synthesis;GO:0000082//G1/S transition of mitotic cell cycle;GO:0006297//nucleotide-excision repair, DNA gap filling;GO:0032201//telomere maintenance via semi-conservative replication;GO:0000724//double-strand break repair via homologous recombination;GO:0000723//telomere maintenance","K10739//replication factor A2","NP_001284487.1//replication protein A 32 kDa subunit isoform 3 [Homo sapiens];NP_001342058.1//replication protein A 32 kDa subunit isoform 4 [Homo sapiens];XP_004025327.2//PREDICTED: LOW QUALITY PROTEIN: replication protein A 32 kDa subunit [Gorilla gorilla gorilla];NP_001125362.2//replication protein A 32 kDa subunit [Pongo abelii]","4;1//3"]
[25972,1197,26.38,25.15,-0.0688861645586552,0.650980088219473,"*",0.530312,"UNC50","GO:0030173//integral component of Golgi membrane;GO:0016021//integral component of membrane;GO:0005637//nuclear inner membrane;GO:0000139//Golgi membrane","GO:0003723//RNA binding","GO:0006810//transport;GO:0007166//cell surface receptor signaling pathway;GO:0015031//protein transport","NA","NP_001317283.1//protein unc-50 homolog isoform 1 [Homo sapiens];XP_006712466.1//PREDICTED: protein unc-50 homolog isoform X1 [Homo sapiens]","6;1//3"]
[7480,2370,2.16,2.06,-0.0683869749802501,0.866405694200829,"*",0.797794,"WNT10B","NA","NA","NA","K01357//wingless-type MMTV integration site family, member 10","XP_005324955.1//protein Wnt-10b [Ictidomys tridecemlineatus]","3//A2MP1"]
[56262,4310,14.86,14.18,-0.0675765832990801,0.57068778814802,"*",0.414172,"LRRC8A","GO:0034702//ion channel complex;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0042802//identical protein binding;GO:0005225//volume-sensitive anion channel activity","GO:0006884//cell volume homeostasis;GO:0007165//signal transduction;GO:0006970//response to osmotic stress;GO:0098656//anion transmembrane transport","K22038//volume-regulated anion channel","XP_015989254.1//PREDICTED: LOW QUALITY PROTEIN: volume-regulated anion channel subunit LRRC8A [Rousettus aegyptiacus]","1//3;3//A2MP1"]
[84720,4044,32.39,30.93,-0.0665416347059221,0.584944937238494,"*",0.42884,"PIGO","GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0051377//mannose-ethanolamine phosphotransferase activity;GO:0003824//catalytic activity","GO:0006506//GPI anchor biosynthetic process;GO:0008152//metabolic process","K05288//phosphatidylinositol glycan, class O","XP_009186845.1//GPI ethanolamine phosphate transferase 3 isoform X3 [Papio anubis];NP_690577.2//GPI ethanolamine phosphate transferase 3 isoform 2 [Homo sapiens];NP_116023.2//GPI ethanolamine phosphate transferase 3 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[9514,1650,13.25,12.66,-0.0657149549095826,0.703907471314234,"*",0.589116,"GAL3ST1","GO:0016020//membrane;GO:0005887//integral component of plasma membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0008146//sulfotransferase activity;GO:0001733//galactosylceramide sulfotransferase activity","GO:0042552//myelination;GO:0009247//glycolipid biosynthetic process;GO:0006487//protein N-linked glycosylation;GO:0007283//spermatogenesis;GO:0006682//galactosylceramide biosynthetic process","K01019//galactosylceramide sulfotransferase [EC:2.8.2.11]","NP_001305038.1//galactosylceramide sulfotransferase isoform 3 [Homo sapiens];XP_011528820.1//PREDICTED: galactosylceramide sulfotransferase isoform X1 [Homo sapiens]","1//3;2//1"]
[55861,1016,9.24,8.83,-0.0654794137675916,0.751457253109633,"*",0.650504,"DBNDD2","GO:0030672//synaptic vesicle membrane","NA","GO:0006469//negative regulation of protein kinase activity;GO:0031175//neuron projection development","K20189//dysbindin","EAW75852.1//chromosome 20 open reading frame 35, isoform CRA_f, partial [Homo sapiens];NP_060948.3//dysbindin domain-containing protein 2 isoform e [Homo sapiens];NP_001041691.2//dysbindin domain-containing protein 2 isoform d [Homo sapiens];NP_001041690.2//dysbindin domain-containing protein 2 isoform c [Homo sapiens]","1//3;3//A2MP1;2//1"]
[57150,2416,1.59,1.52,-0.0649554418407697,0.903435551807229,"*",0.844956,"SMIM8","NA","NA","NA","K05673//ATP-binding cassette, subfamily C (CFTR/MRP), member 4","XP_008992989.1//PREDICTED: small integral membrane protein 8 isoform X5 [Callithrix jacchus];XP_009240335.1//PREDICTED: small integral membrane protein 8 isoform X2 [Pongo abelii]","1//3;2//1;5"]
[10576,1962,147.47,141.01,-0.0646240173371619,0.131057759512629,"*",0.0646428,"CCT2","NA","NA","NA","K09494//T-complex protein 1 subunit beta","XP_010357039.1//PREDICTED: T-complex protein 1 subunit beta [Rhinopithecus roxellana];XP_011905050.1//PREDICTED: T-complex protein 1 subunit beta [Cercocebus atys]","1//3;2//1"]
[6505,3757,0.46,0.44,-0.0641303374197157,0.935879393674739,"*",0.885494,"SLC1A1","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005887//integral component of plasma membrane;GO:0016324//apical plasma membrane;GO:0005886//plasma membrane","GO:0005313//L-glutamate transmembrane transporter activity;GO:0016595//glutamate binding;GO:0015108//chloride transmembrane transporter activity;GO:0046872//metal ion binding;GO:0033229//cysteine transmembrane transporter activity;GO:0005314//high-affinity glutamate transmembrane transporter activity;GO:0015501//glutamate:sodium symporter activity;GO:0015171//amino acid transmembrane transporter activity","GO:0070779//D-aspartate import;GO:0010460//positive regulation of heart rate;GO:0089711//L-glutamate transmembrane transport;GO:0140016//D-aspartate import across plasma membrane;GO:0098712//L-glutamate import across plasma membrane;GO:0051260//protein homooligomerization;GO:0006811//ion transport;GO:0051938//L-glutamate import;GO:0042883//cysteine transport;GO:0140009//L-aspartate import across plasma membrane;GO:0007268//chemical synaptic transmission;GO:1902476//chloride transmembrane transport;GO:0014047//glutamate secretion","K05612//solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter), member 1","NP_004161.4//excitatory amino acid transporter 3 [Homo sapiens]",5]
[192111,2826,50.02,47.85,-0.0639861328075821,0.308200772808132,"*",0.1822116,"PGAM5","GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane","GO:0009400//signal transducer, downstream of receptor, with serine/threonine phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0016791//phosphatase activity;GO:0032403//protein complex binding;GO:0005096//GTPase activator activity","GO:0070266//necroptotic process;GO:0043547//positive regulation of GTPase activity;GO:0016311//dephosphorylation;GO:0016236//macroautophagy","K15637//serine/threonine-protein phosphatase PGAM5 [EC:3.1.3.16]","NP_001164014.1//serine/threonine-protein phosphatase PGAM5, mitochondrial isoform 1 [Homo sapiens];NP_001164015.1//serine/threonine-protein phosphatase PGAM5, mitochondrial isoform 2 [Homo sapiens];NP_612642.2//serine/threonine-protein phosphatase PGAM5, mitochondrial isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[28232,3992,11.61,11.11,-0.0635091554764746,0.720111197205084,"*",0.606464,"SLCO3A1","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005215//transporter activity;GO:0015347//sodium-independent organic anion transmembrane transporter activity","GO:0043252//sodium-independent organic anion transport;GO:0006811//ion transport;GO:0015732//prostaglandin transport","K14353//solute carrier organic anion transporter family, member 3A","NP_037404.2//solute carrier organic anion transporter family member 3A1 isoform 1 [Homo sapiens];NP_001138516.1//solute carrier organic anion transporter family member 3A1 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[388282,1298,13.42,12.85,-0.0626163121189431,0.772881930905963,"*",0.67505,"LOC388282","NA","NA","NA","NA","AAP13354.1//unknown [Homo sapiens]","1//3"]
[54458,1262,292.49,280.16,-0.062136312061407,0.11327989222499,"*",0.054087,"PRR13","GO:0005654//nucleoplasm;GO:0005829//cytosol","NA","NA","K05740//diaphanous 1;K09291//nucleoprotein TPR;K02184//formin 2;K05748//WAS protein family, member 2","XP_011785898.1//PREDICTED: proline-rich protein 13 isoform X3 [Colobus angolensis palliatus];EAW96702.1//proline rich 13, isoform CRA_a [Homo sapiens]","3//A2MP1;2//1"]
[51649,1498,31.3,29.99,-0.0616811349512405,0.653590441716781,"*",0.496678,"MRPS23","GO:0005840//ribosome;GO:0031965//nuclear membrane;GO:0045111//intermediate filament cytoskeleton;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome","GO:0006412//translation;GO:0070126//mitochondrial translational termination;GO:0070125//mitochondrial translational elongation","K17402//small subunit ribosomal protein S23","NP_057154.2//28S ribosomal protein S23, mitochondrial [Homo sapiens]","3//A2MP1"]
[112936,3744,12.51,11.99,-0.0612501307515961,0.624844833528448,"*",0.501198,"VPS26B","GO:0005768//endosome;GO:0030904//retromer complex;GO:0005770//late endosome;GO:0005829//cytosol;GO:0030906//retromer, cargo-selective complex;GO:0005769//early endosome","GO:0008565//protein transporter activity","GO:0016241//regulation of macroautophagy;GO:0006886//intracellular protein transport;GO:0042147//retrograde transport, endosome to Golgi","K18466//vacuolar protein sorting-associated protein 26","NP_443107.1//vacuolar protein sorting-associated protein 26B [Homo sapiens]",4]
[6747,4313,46.04,44.14,-0.0608012038526164,0.134895494779319,"*",0.0669664,"SSR3","GO:0005784//Sec61 translocon complex;GO:0005622//intracellular;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","NA","GO:0006614//SRP-dependent cotranslational protein targeting to membrane","K13251//translocon-associated protein subunit gamma","NP_001295126.1//translocon-associated protein subunit gamma isoform 1 [Homo sapiens];XP_012366145.1//PREDICTED: translocon-associated protein subunit gamma isoform X1 [Nomascus leucogenys];XP_010138580.1//PREDICTED: translocon-associated protein subunit gamma, partial [Buceros rhinoceros silvestris];NP_009038.1//translocon-associated protein subunit gamma isoform 2 [Homo sapiens]","1//3;4"]
[342945,4627,6.11,5.86,-0.0602717153964816,0.680819476298652,"*",0.562846,"ZSCAN22","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_022347978.1//zinc finger and SCAN domain-containing protein 22-like isoform X1 [Enhydra lutris kenyoni];XP_014721031.1//PREDICTED: LOW QUALITY PROTEIN: zinc finger and SCAN domain-containing protein 22 [Equus asinus]","1//3;2//1"]
[1953,7450,2.21,2.12,-0.0599821048282323,0.769062653942742,"*",0.670992,"MEGF6","NA","NA","NA","K02258//cytochrome c oxidase assembly protein subunit 11","BAE19678.1//hypothetical protein, partial [Homo sapiens]","3//A2MP1"]
[5599,5850,3.45,3.31,-0.0597651448583137,0.567703904671445,"*",0.41158,"MAPK8","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0002102//podosome;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005739//mitochondrion;GO:0005737//cytoplasm;GO:0043005//neuron projection","GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0042826//histone deacetylase binding;GO:0035033//histone deacetylase regulator activity;GO:0004705//JUN kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004672//protein kinase activity;GO:0004707//MAP kinase activity;GO:0019899//enzyme binding","GO:0034198//cellular response to amino acid starvation;GO:0007258//JUN phosphorylation;GO:0071260//cellular response to mechanical stimulus;GO:0071222//cellular response to lipopolysaccharide;GO:2000017//positive regulation of determination of dorsal identity;GO:0071310//cellular response to organic substance;GO:0048666//neuron development;GO:0043065//positive regulation of apoptotic process;GO:0032091//negative regulation of protein binding;GO:1902595//regulation of DNA replication origin binding;GO:0071276//cellular response to cadmium ion;GO:0070301//cellular response to hydrogen peroxide;GO:0009612//response to mechanical stimulus;GO:1900740//positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway;GO:0006468//protein phosphorylation;GO:0043066//negative regulation of apoptotic process;GO:0010628//positive regulation of gene expression;GO:2001235//positive regulation of apoptotic signaling pathway;GO:0042752//regulation of circadian rhythm;GO:0018107//peptidyl-threonine phosphorylation;GO:0046686//response to cadmium ion;GO:0001764//neuron migration;GO:0018105//peptidyl-serine phosphorylation;GO:0032880//regulation of protein localization;GO:0090045//positive regulation of deacetylase activity;GO:0097150//neuronal stem cell population maintenance;GO:0051403//stress-activated MAPK cascade;GO:0010468//regulation of gene expression;GO:0071803//positive regulation of podosome assembly;GO:0034614//cellular response to reactive oxygen species;GO:0006950//response to stress;GO:0001503//ossification;GO:0061833//protein localization to tricellular tight junction;GO:0097300//programmed necrotic cell death;GO:0016241//regulation of macroautophagy;GO:0071732//cellular response to nitric oxide;GO:0051247//positive regulation of protein metabolic process;GO:0009411//response to UV;GO:0051090//regulation of DNA binding transcription factor activity;GO:0048511//rhythmic process;GO:0048813//dendrite morphogenesis;GO:0031281//positive regulation of cyclase activity;GO:0007254//JNK cascade;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0048263//determination of dorsal identity","K04440//c-Jun N-terminal kinase [EC:2.7.11.24]","XP_006897773.1//PREDICTED: mitogen-activated protein kinase 8-like isoform X5 [Elephantulus edwardii];XP_006897772.1//PREDICTED: mitogen-activated protein kinase 8-like isoform X4 [Elephantulus edwardii];NP_001265476.1//mitogen-activated protein kinase 8 isoform beta2 [Homo sapiens];XP_006897771.1//PREDICTED: mitogen-activated protein kinase 8-like isoform X3 [Elephantulus edwardii];EDL24854.1//mitogen activated protein kinase 8, isoform CRA_c, partial [Mus musculus];NP_001310249.1//mitogen-activated protein kinase 8 isoform 6 [Homo sapiens]","1//3;3//A2MP1"]
[5444,2567,0.25,0.24,-0.0588936890535686,1.01903040005119,"*",0.996958,"PON1","GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0072562//blood microparticle;GO:0034364//high-density lipoprotein particle;GO:0005576//extracellular region;GO:0034366//spherical high-density lipoprotein particle","GO:0004063//aryldialkylphosphatase activity;GO:0005509//calcium ion binding;GO:0004064//arylesterase activity;GO:0102007//acyl-L-homoserine-lactone lactonohydrolase activity;GO:0042803//protein homodimerization activity;GO:0005543//phospholipid binding","GO:0010875//positive regulation of cholesterol efflux;GO:0046395//carboxylic acid catabolic process;GO:0009605//response to external stimulus;GO:0046470//phosphatidylcholine metabolic process;GO:0019439//aromatic compound catabolic process;GO:0008203//cholesterol metabolic process;GO:0032411//positive regulation of transporter activity;GO:0046434//organophosphate catabolic process;GO:0009636//response to toxic substance;GO:0019372//lipoxygenase pathway;GO:0031667//response to nutrient levels;GO:0070542//response to fatty acid;GO:0051099//positive regulation of binding;GO:1902617//response to fluoride","K01045//arylesterase / paraoxonase [EC:3.1.1.2 3.1.8.1]","NP_000437.3//serum paraoxonase/arylesterase 1 precursor [Homo sapiens]",6]
[83696,6901,4.79,4.6,-0.0583917947918052,0.689880137598069,"*",0.572496,"TRAPPC9","GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0030008//TRAPP complex;GO:0005802//trans-Golgi network;GO:0000139//Golgi membrane","GO:0017112//Rab guanyl-nucleotide exchange factor activity","GO:0030182//neuron differentiation;GO:0021987//cerebral cortex development;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0048208//COPII vesicle coating;GO:0061024//membrane organization","K20306//trafficking protein particle complex subunit 9","XP_011515628.1//PREDICTED: trafficking protein particle complex subunit 9 isoform X1 [Homo sapiens];NP_113654.4//trafficking protein particle complex subunit 9 isoform a [Homo sapiens]","1//3;3//A2MP1;7"]
[55748,5089,16.81,16.15,-0.0577855596548802,0.552514759220598,"*",0.397628,"CNDP2","GO:0070062//extracellular exosome;GO:0005654//nucleoplasm;GO:0005829//cytosol","GO:0004180//carboxypeptidase activity;GO:0103046//alanylglutamate dipeptidase activity;GO:0046872//metal ion binding;GO:0008237//metallopeptidase activity;GO:0102008//cytosolic dipeptidase activity;GO:0016805//dipeptidase activity","GO:0006750//glutathione biosynthetic process","K08660//cytosolic nonspecific dipeptidase [EC:3.4.13.18]","NP_001161971.1//cytosolic non-specific dipeptidase isoform 2 [Homo sapiens];XP_012636662.1//cytosolic non-specific dipeptidase [Microcebus murinus]","1//3;2//1"]
[1846,5646,64.14,61.64,-0.0573574919268614,0.149112907612457,"*",0.0755366,"DUSP4","GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0008330//protein tyrosine/threonine phosphatase activity;GO:0017017//MAP kinase tyrosine/serine/threonine phosphatase activity;GO:1990439//MAP kinase serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0016791//phosphatase activity","GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0035970//peptidyl-threonine dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0001706//endoderm formation;GO:0016311//dephosphorylation;GO:0000188//inactivation of MAPK activity","K04459//dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48]","NP_476499.1//dual specificity protein phosphatase 4 isoform 2 [Homo sapiens];AAB35870.1//threonine, tyrosine phosphatase, partial [Homo sapiens]","6;3//A2MP1"]
[10602,5164,11.93,11.47,-0.0567286516794029,0.452094227433464,"*",0.304132,"CDC42EP3","GO:0012505//endomembrane system;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0005519//cytoskeletal regulatory protein binding;GO:0017049//GTP-Rho binding;GO:0005096//GTPase activator activity","GO:0007266//Rho protein signal transduction;GO:0007165//signal transduction;GO:0031274//positive regulation of pseudopodium assembly;GO:0030838//positive regulation of actin filament polymerization;GO:0008360//regulation of cell shape","K19720//collagen, type III, alpha","NP_006440.2//cdc42 effector protein 3 [Homo sapiens]","4;1//3"]
[476,3754,56.25,54.09,-0.0564911988382639,0.112152969176192,"*",0.0534366,"ATP1A1","GO:0016021//integral component of membrane","GO:0005391//sodium:potassium-exchanging ATPase activity;GO:0046872//metal ion binding;GO:0005524//ATP binding","NA","K01539//sodium/potassium-transporting ATPase subunit alpha [EC:3.6.3.9]","P30714.2//RecName: Full=Sodium/potassium-transporting ATPase subunit alpha-1; Short=Na(+)/K(+) ATPase alpha-1 subunit; AltName: Full=Sodium pump subunit alpha-1; Flags: Precursor","1//3;7"]
[57761,2147,58.48,56.24,-0.056346716879902,0.487705914769623,"*",0.335294,"TRIB3","GO:0031965//nuclear membrane;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0031434//mitogen-activated protein kinase kinase binding;GO:0003714//transcription corepressor activity;GO:0004860//protein kinase inhibitor activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0031625//ubiquitin protein ligase binding;GO:0055106//ubiquitin-protein transferase regulator activity;GO:0019901//protein kinase binding","GO:0034976//response to endoplasmic reticulum stress;GO:0043405//regulation of MAP kinase activity;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0051443//positive regulation of ubiquitin-protein transferase activity;GO:0032092//positive regulation of protein binding;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0019216//regulation of lipid metabolic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006468//protein phosphorylation;GO:0045599//negative regulation of fat cell differentiation;GO:0006351//transcription, DNA-templated;GO:0032869//cellular response to insulin stimulus;GO:0006469//negative regulation of protein kinase activity;GO:0045717//negative regulation of fatty acid biosynthetic process;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0010827//regulation of glucose transport","K19518//tribbles homolog 3","XP_003273513.1//PREDICTED: tribbles homolog 3 isoform X1 [Nomascus leucogenys];NP_066981.2//tribbles homolog 3 isoform 1 [Homo sapiens];NP_001288130.1//tribbles homolog 3 isoform 2 [Homo sapiens]","4;1//3"]
[317762,5671,10.55,10.15,-0.055763271522009,0.647484389994221,"*",0.490984,"CCDC85C","GO:0005923//bicellular tight junction;GO:0043296//apical junction complex","NA","GO:0021987//cerebral cortex development","K13864//solute carrier family 7 (cationic amino acid transporter), member 2;K16758//coiled-coil domain-containing protein 85B","NP_001138467.1//coiled-coil domain-containing protein 85C [Homo sapiens]","1//3"]
[80381,2964,36.38,35.01,-0.0553784812229823,0.259370377709522,"*",0.1480168,"CD276","GO:0070062//extracellular exosome;GO:0009897//external side of plasma membrane;GO:0016021//integral component of membrane","GO:0005102//receptor binding","GO:0042110//T cell activation;GO:0008283//cell proliferation;GO:0045078//positive regulation of interferon-gamma biosynthetic process;GO:0042102//positive regulation of T cell proliferation;GO:0006955//immune response;GO:0050776//regulation of immune response","K06746//immune costimulatory protein B7-H3","NP_079516.1//CD276 antigen isoform b precursor [Homo sapiens];XP_015308533.1//PREDICTED: CD276 antigen isoform X1 [Macaca fascicularis];NP_001019907.1//CD276 antigen isoform a precursor [Homo sapiens]","1//3;2//1"]
[339745,5741,1.87,1.8,-0.055041363557962,0.846286651207464,"*",0.772222,"SPOPL","GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0031463//Cul3-RING ubiquitin ligase complex;GO:0019005//SCF ubiquitin ligase complex","GO:0031625//ubiquitin protein ligase binding","GO:0031397//negative regulation of protein ubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0030162//regulation of proteolysis;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process","K10523//speckle-type POZ protein","XP_020746107.1//speckle-type POZ protein-like isoform X1 [Odocoileus virginianus texanus]","2//1"]
[10395,5870,8.08,7.78,-0.0545851377656029,0.429253933649289,"*",0.2835,"DLC1","GO:0005634//nucleus;GO:0030864//cortical actin cytoskeleton;GO:0005901//caveola;GO:0005925//focal adhesion;GO:0005829//cytosol;GO:0032587//ruffle membrane;GO:0005737//cytoplasm","GO:0008289//lipid binding;GO:0042169//SH2 domain binding;GO:0005096//GTPase activator activity","GO:0035307//positive regulation of protein dephosphorylation;GO:0021575//hindbrain morphogenesis;GO:0032956//regulation of actin cytoskeleton organization;GO:0003007//heart morphogenesis;GO:0051497//negative regulation of stress fiber assembly;GO:1900119//positive regulation of execution phase of apoptosis;GO:0008285//negative regulation of cell proliferation;GO:0048041//focal adhesion assembly;GO:0007165//signal transduction;GO:0030036//actin cytoskeleton organization;GO:0030336//negative regulation of cell migration;GO:0008360//regulation of cell shape;GO:0051895//negative regulation of focal adhesion assembly;GO:0006915//apoptotic process;GO:0030900//forebrain development;GO:0035023//regulation of Rho protein signal transduction;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0001843//neural tube closure;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0035024//negative regulation of Rho protein signal transduction","K20632//deleted in liver cancer protein","NP_079043.3//rho GTPase-activating protein 7 isoform 3 [Homo sapiens];NP_006085.2//rho GTPase-activating protein 7 isoform 2 [Homo sapiens];AAH54511.1//Deleted in liver cancer 1 [Homo sapiens];NP_872584.2//rho GTPase-activating protein 7 isoform 1 [Homo sapiens];NP_001303597.1//rho GTPase-activating protein 7 isoform 5 [Homo sapiens]","4;1//3;3//A2MP1;2//1"]
[1641,9150,0.27,0.26,-0.0544477840223765,1.02176443529185,"*",0.99394,"DCX","GO:0005856//cytoskeleton;GO:0005875//microtubule associated complex;GO:0005874//microtubule;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005737//cytoplasm;GO:0043005//neuron projection","GO:0008017//microtubule binding;GO:0019901//protein kinase binding","GO:0007399//nervous system development;GO:0048675//axon extension;GO:0021860//pyramidal neuron development;GO:0021766//hippocampus development;GO:0035556//intracellular signal transduction;GO:0007417//central nervous system development;GO:0048813//dendrite morphogenesis;GO:0001764//neuron migration;GO:0021952//central nervous system projection neuron axonogenesis;GO:0021819//layer formation in cerebral cortex","K16579//neuronal migration protein doublecortin","XP_022271525.1//neuronal migration protein doublecortin isoform X1 [Canis lupus familiaris];NP_000546.2//neuronal migration protein doublecortin isoform a [Homo sapiens];XP_022271528.1//neuronal migration protein doublecortin isoform X4 [Canis lupus familiaris];XP_016799488.1//PREDICTED: neuronal migration protein doublecortin isoform X3 [Pan troglodytes];XP_002832043.2//PREDICTED: neuronal migration protein doublecortin isoform X2 [Pongo abelii]","1//3;3//A2MP1;2//1"]
[27315,1817,22.58,21.75,-0.0540300851495477,0.70435173315384,"*",0.589576,"PGAP2","GO:0005634//nucleus;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0000139//Golgi membrane","GO:0008565//protein transporter activity","GO:1902230//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage;GO:0006506//GPI anchor biosynthetic process;GO:0042770//signal transduction in response to DNA damage;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator","K03006//DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6];K15263//cell growth-regulating nucleolar protein;K21125//mucin-5AC","XP_022263440.1//post-GPI attachment to proteins factor 2 isoform X1 [Canis lupus familiaris];XP_011518295.2//PREDICTED: post-GPI attachment to proteins factor 2 isoform X4 [Homo sapiens];NP_001269967.1//post-GPI attachment to proteins factor 2 isoform 9 [Homo sapiens];NP_001333326.1//post-GPI attachment to proteins factor 2 isoform 12 [Homo sapiens];NP_001269969.1//post-GPI attachment to proteins factor 2 isoform 11 [Homo sapiens];OWK17835.1//PGAP2 [Cervus elaphus hippelaphus];NP_001243166.1//post-GPI attachment to proteins factor 2 isoform 5 [Homo sapiens];NP_001243165.1//post-GPI attachment to proteins factor 2 isoform 4 [Homo sapiens];NP_001269968.1//post-GPI attachment to proteins factor 2 isoform 10 [Homo sapiens];NP_001138910.1//post-GPI attachment to proteins factor 2 isoform 2 [Homo sapiens];NP_001333331.1//post-GPI attachment to proteins factor 2 isoform 15 [Homo sapiens];ELK32341.1//Post-GPI attachment to proteins factor 2, partial [Myotis davidii]","1//3;3//A2MP1;2//1"]
[219844,1892,12.33,11.88,-0.0536379636020732,0.758389601787774,"*",0.658594,"HYLS1","GO:0005929//cilium;GO:0005814//centriole;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005813//centrosome;GO:0005886//plasma membrane;GO:0005737//cytoplasm","NA","GO:0060271//cilium assembly","K16472//hydrolethalus syndrome protein 1","XP_015291404.1//PREDICTED: hydrolethalus syndrome protein 1 homolog isoform X2 [Macaca fascicularis];XP_008019603.1//PREDICTED: hydrolethalus syndrome protein 1 isoform X1 [Chlorocebus sabaeus]","1//3;2//1"]
[8226,2149,13.72,13.23,-0.0524674198941355,0.901148541982175,"*",0.841858,"PUDP","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:1990738//pseudouridine 5'-phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity","GO:0008152//metabolic process;GO:0043097//pyrimidine nucleoside salvage;GO:0009117//nucleotide metabolic process","K17623//pseudouridine 5'-phosphatase [EC:3.1.3.96]","NP_001171607.1//pseudouridine-5'-phosphatase isoform d [Homo sapiens];NP_001129037.1//pseudouridine-5'-phosphatase isoform a [Homo sapiens];NP_001171606.1//pseudouridine-5'-phosphatase isoform c [Homo sapiens];NP_036212.3//pseudouridine-5'-phosphatase isoform b [Homo sapiens]","1//3;4"]
[23086,9875,1.68,1.62,-0.0524674198941355,0.915684494205408,"*",0.860654,"EXPH5","GO:0005768//endosome;GO:0005622//intracellular","GO:0017137//Rab GTPase binding","GO:0050714//positive regulation of protein secretion;GO:0003334//keratinocyte development;GO:0006886//intracellular protein transport;GO:0045921//positive regulation of exocytosis;GO:0071985//multivesicular body sorting pathway","K22236//exophilin-5","NP_001294948.1//exophilin-5 isoform 2 [Homo sapiens];NP_055880.2//exophilin-5 isoform 1 [Homo sapiens]","1//3;2//1"]
[80028,6245,14.48,13.97,-0.0517295816737423,0.0644224496638535,"*",0.0281944,"FBXL18","NA","NA","NA","K10284//F-box and leucine-rich repeat protein 18","NP_001308142.1//F-box/LRR-repeat protein 18 isoform 1 [Homo sapiens];XP_003895742.3//F-box/LRR-repeat protein 18 isoform X1 [Papio anubis]","1//3;5"]
[1723,2438,10.88,10.5,-0.0512892286968546,0.781725912521441,"*",0.684732,"DHODH","GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0043025//neuronal cell body","GO:0004152//dihydroorotate dehydrogenase activity;GO:0010181//FMN binding;GO:0008144//drug binding;GO:0048039//ubiquinone binding","GO:0007595//lactation;GO:0042493//response to drug;GO:0007565//female pregnancy;GO:0046134//pyrimidine nucleoside biosynthetic process;GO:1903576//response to L-arginine;GO:0044205//'de novo' UMP biosynthetic process;GO:0043065//positive regulation of apoptotic process;GO:0042594//response to starvation;GO:0031000//response to caffeine;GO:0090140//regulation of mitochondrial fission;GO:0006207//'de novo' pyrimidine nucleobase biosynthetic process","K00254//dihydroorotate dehydrogenase [EC:1.3.5.2]","NP_001352.2//dihydroorotate dehydrogenase (quinone), mitochondrial [Homo sapiens]",4]
[23132,9916,2.58,2.49,-0.0512253233551731,0.710398979777628,"*",0.595972,"RAD54L2","NA","GO:0005524//ATP binding","NA","K10876//RAD54-like protein 2 [EC:3.6.4.12]","XP_021583201.1//helicase ARIP4 isoform X3 [Ictidomys tridecemlineatus];XP_001169759.1//PREDICTED: helicase ARIP4 isoform X1 [Pan troglodytes]","1//3;3//A2MP1"]
[54857,2374,0.29,0.28,-0.0506260730699678,1.01922750172833,"*",0.996768,"GDPD2","GO:0005884//actin filament;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0030027//lamellipodium;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0047394//glycerophosphoinositol inositolphosphodiesterase activity;GO:0008889//glycerophosphodiester phosphodiesterase activity","GO:0090527//actin filament reorganization;GO:0045669//positive regulation of osteoblast differentiation;GO:0006629//lipid metabolic process","K01124//glycerophosphoinositol inositolphosphodiesterase [EC:3.1.4.43]","NP_001164663.1//glycerophosphoinositol inositolphosphodiesterase GDPD2 isoform 1 [Homo sapiens];NP_060181.2//glycerophosphoinositol inositolphosphodiesterase GDPD2 isoform 2 [Homo sapiens];XP_009437508.1//PREDICTED: glycerophosphoinositol inositolphosphodiesterase GDPD2 isoform X2 [Pan troglodytes]","1//3;3//A2MP1"]
[109703458,3266,4.71,4.55,-0.0498605145267246,0.699779011542497,"*",0.584478,"HTD2","GO:0005759//mitochondrial matrix;GO:0005730//nucleolus;GO:0005739//mitochondrion","GO:0018812//3-hydroxyacyl-CoA dehydratase activity","GO:0046949//fatty-acyl-CoA biosynthetic process;GO:0006631//fatty acid metabolic process","K12581//CCR4-NOT transcription complex subunit 7/8;K14529//ribonuclease P protein subunit RPP14 [EC:3.1.26.5]","NP_001335643.1//hydroxyacyl-thioester dehydratase type 2, mitochondrial [Homo sapiens]","1//3"]
[51226,939,8.01,7.74,-0.0494686762642998,0.894481739936832,"*",0.833278,"COPZ2","GO:0030126//COPI vesicle coat;GO:0030133//transport vesicle;GO:0005829//cytosol;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005801//cis-Golgi network;GO:0000139//Golgi membrane","NA","GO:0006886//intracellular protein transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0015031//protein transport","K20472//coatomer subunit zeta","NP_057513.1//coatomer subunit zeta-2 [Homo sapiens]","3//A2MP1"]
[9441,3184,3.9,3.77,-0.0489096004809464,0.859247614319809,"*",0.788836,"MED26","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016592//mediator complex","GO:0003713//transcription coactivator activity;GO:0001104//RNA polymerase II transcription cofactor activity","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006367//transcription initiation from RNA polymerase II promoter","K15169//mediator of RNA polymerase II transcription subunit 26","NP_004822.2//mediator of RNA polymerase II transcription subunit 26 [Homo sapiens]","3//A2MP1"]
[2098,1208,45.55,44.05,-0.0483090348816371,0.687179981874481,"*",0.56961,"ESD","GO:0070062//extracellular exosome;GO:0005788//endoplasmic reticulum lumen;GO:0031410//cytoplasmic vesicle;GO:0005737//cytoplasm","GO:0047374//methylumbelliferyl-acetate deacetylase activity;GO:0042802//identical protein binding;GO:0052689//carboxylic ester hydrolase activity;GO:0018738//S-formylglutathione hydrolase activity;GO:0016788//hydrolase activity, acting on ester bonds","GO:0046294//formaldehyde catabolic process;GO:1901687//glutathione derivative biosynthetic process","K01070//S-formylglutathione hydrolase [EC:3.1.2.12]","XP_009190178.1//S-formylglutathione hydrolase isoform X1 [Papio anubis]","1//3"]
[23396,4955,10.11,9.78,-0.0478766269507809,0.676869785562633,"*",0.558818,"PIP5K1C","GO:0010008//endosome membrane;GO:0005654//nucleoplasm;GO:0005925//focal adhesion;GO:0098793//presynapse;GO:0001931//uropod;GO:0032587//ruffle membrane;GO:0001891//phagocytic cup;GO:0005829//cytosol","GO:0016307//phosphatidylinositol phosphate kinase activity;GO:0052812//phosphatidylinositol-3,4-bisphosphate 5-kinase activity;GO:0005524//ATP binding;GO:0016308//1-phosphatidylinositol-4-phosphate 5-kinase activity;GO:0052811//1-phosphatidylinositol-3-phosphate 4-kinase activity","GO:0048488//synaptic vesicle endocytosis;GO:0030593//neutrophil chemotaxis;GO:0030036//actin cytoskeleton organization;GO:0014066//regulation of phosphatidylinositol 3-kinase signaling;GO:0072583//clathrin-dependent endocytosis;GO:0006661//phosphatidylinositol biosynthetic process;GO:0061024//membrane organization;GO:0098609//cell-cell adhesion;GO:0016079//synaptic vesicle exocytosis;GO:0034333//adherens junction assembly;GO:0006909//phagocytosis","K00889//1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]","XP_007992983.1//PREDICTED: phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X1 [Chlorocebus sabaeus];XP_010365580.1//PREDICTED: phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X1 [Rhinopithecus roxellana]","1//3;2//1"]
[84282,2086,20.2,19.55,-0.0471866854444423,0.657951678076422,"*",0.537886,"RNF135","GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0043021//ribonucleoprotein complex binding;GO:0004842//ubiquitin-protein transferase activity","GO:0032728//positive regulation of interferon-beta production;GO:0016567//protein ubiquitination;GO:0016579//protein deubiquitination;GO:0045088//regulation of innate immune response;GO:0032480//negative regulation of type I interferon production;GO:0045087//innate immune response","K16272//E3 ubiquitin-protein ligase RNF135 [EC:2.3.2.27]","XP_002827271.2//PREDICTED: E3 ubiquitin-protein ligase RNF135 isoform X1 [Pongo abelii];XP_003778828.2//PREDICTED: E3 ubiquitin-protein ligase RNF135 isoform X3 [Pongo abelii];XP_009249753.1//PREDICTED: E3 ubiquitin-protein ligase RNF135 isoform X2 [Pongo abelii]","1//3;3//A2MP1"]
[2395,7170,4.76,4.61,-0.0461948228786054,0.774637681358848,"*",0.676632,"FXN","GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0005739//mitochondrion","GO:0034986//iron chaperone activity;GO:0051537//2 iron, 2 sulfur cluster binding;GO:0004322//ferroxidase activity;GO:0008199//ferric iron binding;GO:0051536//iron-sulfur cluster binding;GO:0008198//ferrous iron binding","GO:0006879//cellular iron ion homeostasis;GO:0051349//positive regulation of lyase activity;GO:0030307//positive regulation of cell growth;GO:0044281//small molecule metabolic process;GO:0090201//negative regulation of release of cytochrome c from mitochondria;GO:0006783//heme biosynthetic process;GO:0009792//embryo development ending in birth or egg hatching;GO:0006119//oxidative phosphorylation;GO:0046621//negative regulation of organ growth;GO:0040015//negative regulation of multicellular organism growth;GO:0018283//iron incorporation into metallo-sulfur cluster;GO:0043085//positive regulation of catalytic activity;GO:0070301//cellular response to hydrogen peroxide;GO:0016540//protein autoprocessing;GO:0010039//response to iron ion;GO:0043066//negative regulation of apoptotic process;GO:1904234//positive regulation of aconitate hydratase activity;GO:0009060//aerobic respiration;GO:0006811//ion transport;GO:0007005//mitochondrion organization;GO:0010722//regulation of ferrochelatase activity;GO:0016226//iron-sulfur cluster assembly;GO:0007628//adult walking behavior;GO:0019230//proprioception;GO:1904231//positive regulation of succinate dehydrogenase activity;GO:0008284//positive regulation of cell proliferation","K19054//frataxin [EC:1.16.3.1]","NP_000135.2//frataxin, mitochondrial isoform 1 preproprotein [Homo sapiens];NP_852090.1//frataxin, mitochondrial isoform 2 preproprotein [Homo sapiens]","4;2//1"]
[79583,2925,4.15,4.02,-0.0459158350553588,0.892237145623235,"*",0.830796,"TMEM231","GO:0060170//ciliary membrane;GO:0035869//ciliary transition zone;GO:0016021//integral component of membrane;GO:0036038//MKS complex","NA","GO:0043010//camera-type eye development;GO:0001701//in utero embryonic development;GO:0042733//embryonic digit morphogenesis;GO:0060271//cilium assembly;GO:0001944//vasculature development;GO:0032880//regulation of protein localization;GO:0007224//smoothened signaling pathway;GO:0060563//neuroepithelial cell differentiation","K19362//transmembrane protein 231","XP_008953160.1//PREDICTED: transmembrane protein 231 isoform X1 [Pan paniscus];NP_001070886.1//transmembrane protein 231 isoform 2 [Homo sapiens]","2//1"]
[22938,2155,34.92,33.83,-0.045750381835452,0.632551595415118,"*",0.5113,"SNW1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000785//chromatin;GO:0016607//nuclear speck;GO:0016363//nuclear matrix;GO:0005737//cytoplasm;GO:0071013//catalytic step 2 spliceosome;GO:0005681//spliceosomal complex;GO:0016604//nuclear body;GO:0071014//post-mRNA release spliceosomal complex;GO:0071141//SMAD protein complex","GO:0042809//vitamin D receptor binding;GO:0003723//RNA binding;GO:0003714//transcription corepressor activity;GO:0042974//retinoic acid receptor binding;GO:0035257//nuclear hormone receptor binding;GO:0050681//androgen receptor binding;GO:0003713//transcription coactivator activity;GO:0005112//Notch binding;GO:0046332//SMAD binding;GO:0019899//enzyme binding","GO:0048385//regulation of retinoic acid receptor signaling pathway;GO:0043923//positive regulation by host of viral transcription;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0000350//generation of catalytic spliceosome for second transesterification step;GO:0070564//positive regulation of vitamin D receptor signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0051571//positive regulation of histone H3-K4 methylation;GO:0000398//mRNA splicing, via spliceosome;GO:0048384//retinoic acid receptor signaling pathway;GO:0006351//transcription, DNA-templated;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0016032//viral process;GO:0071300//cellular response to retinoic acid;GO:0048026//positive regulation of mRNA splicing, via spliceosome;GO:0050769//positive regulation of neurogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0070562//regulation of vitamin D receptor signaling pathway;GO:0007219//Notch signaling pathway;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0014010//Schwann cell proliferation","K06063//SNW domain-containing protein 1","XP_006157174.1//PREDICTED: SNW domain-containing protein 1 [Tupaia chinensis];XP_008061519.1//SNW domain-containing protein 1 isoform X1 [Carlito syrichta]","1//3;2//1"]
[80019,1711,14.09,13.66,-0.0447141280195461,0.813697960011186,"*",0.72863,"UBTD1","NA","GO:0043130//ubiquitin binding","NA","NA","NP_079230.1//ubiquitin domain-containing protein 1 [Homo sapiens]",4]
[5516,1987,42.8,41.5,-0.0444994601668597,0.63293356914976,"*",0.511688,"PPP2CB","GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0000775//chromosome, centromeric region","GO:0046872//metal ion binding;GO:0004721//phosphoprotein phosphatase activity","NA","K04382//serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]","XP_021092390.1//serine/threonine-protein phosphatase 2A catalytic subunit beta isoform [Heterocephalus glaber]","1//3"]
[27352,2930,6.35,6.16,-0.0438262409646267,0.760172846774194,"*",0.660904,"SGSM3","GO:0012505//endomembrane system;GO:0005921//gap junction;GO:0005829//cytosol","GO:0017137//Rab GTPase binding;GO:0005096//GTPase activator activity","GO:0006886//intracellular protein transport;GO:0090630//activation of GTPase activity;GO:0032483//regulation of Rab protein signal transduction;GO:0045732//positive regulation of protein catabolic process;GO:0031338//regulation of vesicle fusion;GO:0043547//positive regulation of GTPase activity;GO:0007050//cell cycle arrest;GO:0032486//Rap protein signal transduction;GO:0048227//plasma membrane to endosome transport","K20176//small G protein signaling modulator 3","NP_056520.2//small G protein signaling modulator 3 isoform 1 [Homo sapiens];NP_001336969.1//small G protein signaling modulator 3 isoform 4 [Homo sapiens];NP_001336973.1//small G protein signaling modulator 3 isoform 8 [Homo sapiens];NP_001336968.1//small G protein signaling modulator 3 isoform 3 [Homo sapiens];NP_001336971.1//small G protein signaling modulator 3 isoform 6 [Homo sapiens];NP_001288778.1//small G protein signaling modulator 3 isoform 2 [Homo sapiens];NP_001336970.1//small G protein signaling modulator 3 isoform 5 [Homo sapiens]","1//3;5"]
[79644,4089,5.02,4.87,-0.0437655918684296,0.847253071604938,"*",0.773316,"SRD5A3","GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0102389//polyprenol reductase activity;GO:0016628//oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;GO:0047751//cholestenone 5-alpha-reductase activity;GO:0003865//3-oxo-5-alpha-steroid 4-dehydrogenase activity","GO:0016095//polyprenol catabolic process;GO:0006486//protein glycosylation;GO:0006489//dolichyl diphosphate biosynthetic process;GO:0019348//dolichol metabolic process;GO:0006488//dolichol-linked oligosaccharide biosynthetic process;GO:0006702//androgen biosynthetic process","K12345//3-oxo-5-alpha-steroid 4-dehydrogenase 3 [EC:1.3.1.22 1.3.1.94]","NP_078868.1//polyprenol reductase [Homo sapiens]",4]
[131474,1494,19.81,19.22,-0.043620544115736,0.902290395501406,"*",0.843772,"CHCHD4","GO:0005758//mitochondrial intermembrane space;GO:0005739//mitochondrion","GO:0015035//protein disulfide oxidoreductase activity","GO:0051084//'de novo' posttranslational protein folding;GO:0022417//protein maturation by protein folding;GO:0045041//protein import into mitochondrial intermembrane space","K17782//mitochondrial intermembrane space import and assembly protein 40","NP_001091972.1//mitochondrial intermembrane space import and assembly protein 40 isoform 1 [Homo sapiens];NP_653237.1//mitochondrial intermembrane space import and assembly protein 40 isoform 2 [Homo sapiens]","1//3;2//1"]
[54883,3112,16.55,16.06,-0.0433593241772658,0.732050800029614,"*",0.618994,"CWC25","GO:0005654//nucleoplasm;GO:0016607//nuclear speck","NA","GO:0000398//mRNA splicing, via spliceosome","K12182//hepatocyte growth factor-regulated tyrosine kinase substrate;K01064//wingless-type MMTV integration site family, member 9","NP_060218.1//pre-mRNA-splicing factor CWC25 homolog [Homo sapiens]",4]
[101928991,4432,1.69,1.64,-0.0433274316641005,0.89650148768539,"*",0.836282,"CCDC92B","NA","NA","NA","K16452//coiled-coil domain-containing protein 92","XP_011727190.1//PREDICTED: coiled-coil domain-containing protein 92 [Macaca nemestrina]","1//3"]
[54758,1934,12.89,12.51,-0.0431704741958312,0.745972963440237,"*",0.645056,"KLHDC4","NA","NA","NA","K03006//DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6];K13172//serine/arginine repetitive matrix protein 2","NP_001171783.1//kelch domain-containing protein 4 isoform 3 [Homo sapiens];NP_060036.2//kelch domain-containing protein 4 isoform 1 [Homo sapiens];NP_001171785.1//kelch domain-containing protein 4 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[80737,2914,0.68,0.66,-0.043068721891886,0.941307761166458,"*",0.893164,"VWA7","GO:0005576//extracellular region","NA","NA","K17341//hemicentin","NP_079534.2//von Willebrand factor A domain-containing protein 7 precursor [Homo sapiens]","2//1"]
[285,5114,0.34,0.33,-0.043068721891886,1.02144074143582,"*",0.994904,"ANGPT2","GO:0005634//nucleus;GO:0005615//extracellular space;GO:0042995//cell projection;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0046872//metal ion binding;GO:0030971//receptor tyrosine kinase binding;GO:0005102//receptor binding","GO:0031100//animal organ regeneration;GO:0014070//response to organic cyclic compound;GO:0060135//maternal process involved in female pregnancy;GO:0050928//negative regulation of positive chemotaxis;GO:0071363//cellular response to growth factor stimulus;GO:0009749//response to glucose;GO:0045766//positive regulation of angiogenesis;GO:0072012//glomerulus vasculature development;GO:0009612//response to mechanical stimulus;GO:0007165//signal transduction;GO:0001525//angiogenesis;GO:0050900//leukocyte migration;GO:0016525//negative regulation of angiogenesis;GO:0014823//response to activity;GO:0048014//Tie signaling pathway;GO:0001666//response to hypoxia;GO:0007281//germ cell development;GO:0009314//response to radiation;GO:0010812//negative regulation of cell-substrate adhesion;GO:0043537//negative regulation of blood vessel endothelial cell migration","K05466//angiopoietin 2","XP_010379683.1//PREDICTED: angiopoietin-2 isoform X2 [Rhinopithecus roxellana];XP_010379682.1//PREDICTED: angiopoietin-2 isoform X1 [Rhinopithecus roxellana];XP_010379684.1//PREDICTED: angiopoietin-2 isoform X3 [Rhinopithecus roxellana]","1//3;2//1"]
[55347,2785,11.23,10.9,-0.0430297927363124,0.782323025512756,"*",0.685304,"ABHD10","GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0005739//mitochondrion","GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0016787//hydrolase activity;GO:0102390//mycophenolic acid acyl-glucuronide esterase activity","GO:0052695//cellular glucuronidation;GO:0019391//glucuronoside catabolic process","K13702//abhydrolase domain-containing protein 10 [EC:3.1.1.93]","NP_001258998.1//mycophenolic acid acyl-glucuronide esterase, mitochondrial isoform 2 [Homo sapiens];NP_060864.1//mycophenolic acid acyl-glucuronide esterase, mitochondrial isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[219854,4003,4.43,4.3,-0.042970038965558,0.861459432426906,"*",0.791298,"TMEM218","GO:0005929//cilium;GO:0016021//integral component of membrane","NA","NA","NA","NP_001245168.1//transmembrane protein 218 isoform 1 [Homo sapiens]","1//3;2//1"]
[81559,2715,17.04,16.54,-0.0429661010545636,0.740187790986283,"*",0.638478,"TRIM11","GO:0005622//intracellular","GO:0008270//zinc ion binding","NA","K10650//tripartite motif-containing protein 11 [EC:2.3.2.27]","XP_011941598.1//PREDICTED: E3 ubiquitin-protein ligase TRIM11 isoform X1 [Cercocebus atys]","2//1"]
[5550,2943,16.7,16.21,-0.0429640118438729,0.732927718449432,"*",0.629692,"PREP","NA","NA","NA","K01322//prolyl oligopeptidase [EC:3.4.21.26]","XP_003898012.3//prolyl endopeptidase isoform X1 [Papio anubis]",4]
[123207,847,42.08,40.85,-0.0427986262592565,0.785650211458112,"*",0.694514,"C15orf40","NA","NA","NA","K09131//uncharacterized protein","NP_653198.2//UPF0235 protein C15orf40 isoform a [Homo sapiens];NP_001153585.1//UPF0235 protein C15orf40 isoform b [Homo sapiens];NP_001153588.1//UPF0235 protein C15orf40 isoform e [Homo sapiens];NP_001153587.1//UPF0235 protein C15orf40 isoform d [Homo sapiens];NP_001153586.1//UPF0235 protein C15orf40 isoform c [Homo sapiens]","1//3;2//1"]
[80304,3897,7.53,7.31,-0.042778458719491,0.710315382249757,"*",0.595724,"WDCP","NA","GO:0019900//kinase binding","GO:0051259//protein oligomerization","NA","NP_079479.1//WD repeat and coiled-coil-containing protein isoform 1 [Homo sapiens];NP_001135791.1//WD repeat and coiled-coil-containing protein isoform 2 [Homo sapiens]","1//3;2//1"]
[51184,1580,12.36,12,-0.0426443374084937,0.685764278676137,"*",0.568136,"GPN3","GO:0043234//protein complex;GO:0005622//intracellular","GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:1990022//RNA polymerase III complex localization to nucleus;GO:0044376//RNA polymerase II complex import to nucleus","K06883//uncharacterized protein","XP_005253953.3//PREDICTED: GPN-loop GTPase 3 isoform X1 [Homo sapiens];NP_001157844.1//GPN-loop GTPase 3 isoform 2 [Homo sapiens];XP_009424519.2//PREDICTED: GPN-loop GTPase 3 isoform X1 [Pan troglodytes]","1//3;3//A2MP1"]
[26020,6930,38.18,37.07,-0.0425649875847818,0.407427639161377,"*",0.265208,"LRP10","GO:0016020//membrane;GO:0005905//clathrin-coated pit;GO:0016021//integral component of membrane","GO:0005041//low-density lipoprotein receptor activity","GO:0006869//lipid transport;GO:0048839//inner ear development;GO:0006629//lipid metabolic process","K20050//low-density lipoprotein receptor-related protein 3/10/12","XP_004054968.1//PREDICTED: low-density lipoprotein receptor-related protein 10 [Gorilla gorilla gorilla]","1//3;4"]
[3320,3376,552.5,536.51,-0.0423694029053918,0.00989321907870874,"*",0.003415,"HSP90AA1","GO:0034774//secretory granule lumen;GO:0016020//membrane;GO:0032587//ruffle membrane;GO:0042470//melanosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005576//extracellular region;GO:1904813//ficolin-1-rich granule lumen;GO:0043202//lysosomal lumen;GO:0005886//plasma membrane;GO:0070062//extracellular exosome;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0043209//myelin sheath;GO:0043234//protein complex;GO:0071682//endocytic vesicle lumen","GO:0030235//nitric-oxide synthase regulator activity;GO:0003723//RNA binding;GO:0005524//ATP binding;GO:1990782//protein tyrosine kinase binding;GO:0070182//DNA polymerase binding;GO:0004713//protein tyrosine kinase activity;GO:0000166//nucleotide binding;GO:0016887//ATPase activity;GO:0042826//histone deacetylase binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0023026//MHC class II protein complex binding;GO:0030911//TPR domain binding;GO:0051082//unfolded protein binding;GO:0051020//GTPase binding;GO:0097718//disordered domain specific binding","GO:0006986//response to unfolded protein;GO:0006950//response to stress;GO:0051973//positive regulation of telomerase activity;GO:0043335//protein unfolding;GO:0006839//mitochondrial transport;GO:0046677//response to antibiotic;GO:0097711//ciliary basal body-plasma membrane docking;GO:0007004//telomere maintenance via telomerase;GO:0043312//neutrophil degranulation;GO:0006457//protein folding;GO:1905323//telomerase holoenzyme complex assembly;GO:0031396//regulation of protein ubiquitination;GO:0045040//protein import into mitochondrial outer membrane;GO:0007165//signal transduction;GO:0009409//response to cold;GO:0043254//regulation of protein complex assembly;GO:0038128//ERBB2 signaling pathway;GO:0009408//response to heat;GO:1900034//regulation of cellular response to heat;GO:0051131//chaperone-mediated protein complex assembly;GO:0010389//regulation of G2/M transition of mitotic cell cycle;GO:0006898//receptor-mediated endocytosis;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0050999//regulation of nitric-oxide synthase activity;GO:0000086//G2/M transition of mitotic cell cycle;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0061684//chaperone-mediated autophagy;GO:0042026//protein refolding;GO:0050821//protein stabilization","K04079//molecular chaperone HtpG","NP_001017963.2//heat shock protein HSP 90-alpha isoform 1 [Homo sapiens];XP_010967090.1//PREDICTED: heat shock protein HSP 90-alpha [Camelus bactrianus]","3//A2MP1;2//1"]
[5777,2283,10.03,9.74,-0.0423279285298384,0.810010852249596,"*",0.722438,"PTPN6","GO:1904724//tertiary granule lumen;GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0035580//specific granule lumen;GO:0042105//alpha-beta T cell receptor complex;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0005911//cell-cell junction;GO:0005829//cytosol;GO:0043234//protein complex;GO:0005576//extracellular region","GO:0050839//cell adhesion molecule binding;GO:0001784//phosphotyrosine residue binding;GO:0005001//transmembrane receptor protein tyrosine phosphatase activity;GO:0017124//SH3 domain binding;GO:0004725//protein tyrosine phosphatase activity;GO:0042169//SH2 domain binding;GO:0019901//protein kinase binding","GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:0043407//negative regulation of MAP kinase activity;GO:0050860//negative regulation of T cell receptor signaling pathway;GO:0042130//negative regulation of T cell proliferation;GO:0033277//abortive mitotic cell cycle;GO:0008285//negative regulation of cell proliferation;GO:0045577//regulation of B cell differentiation;GO:0030154//cell differentiation;GO:0042267//natural killer cell mediated cytotoxicity;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0006915//apoptotic process;GO:0050859//negative regulation of B cell receptor signaling pathway;GO:0002244//hematopoietic progenitor cell differentiation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0051279//regulation of release of sequestered calcium ion into cytosol;GO:0035556//intracellular signal transduction;GO:0030168//platelet activation;GO:0031295//T cell costimulation;GO:0008283//cell proliferation;GO:0030220//platelet formation;GO:0043312//neutrophil degranulation;GO:0006470//protein dephosphorylation;GO:0050732//negative regulation of peptidyl-tyrosine phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0007186//G-protein coupled receptor signaling pathway;GO:0050853//B cell receptor signaling pathway;GO:0035855//megakaryocyte development;GO:0002924//negative regulation of humoral immune response mediated by circulating immunoglobulin;GO:0050900//leukocyte migration;GO:0060338//regulation of type I interferon-mediated signaling pathway;GO:0070527//platelet aggregation;GO:0033630//positive regulation of cell adhesion mediated by integrin;GO:0008284//positive regulation of cell proliferation","K05697//tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]","NP_536859.1//tyrosine-protein phosphatase non-receptor type 6 isoform 3 [Homo sapiens];NP_536858.1//tyrosine-protein phosphatase non-receptor type 6 isoform 2 [Homo sapiens];XP_011838424.1//PREDICTED: tyrosine-protein phosphatase non-receptor type 6 isoform X1 [Mandrillus leucophaeus]","4;3//A2MP1;5"]
[51752,4935,4.87,4.73,-0.0420815887429469,0.79450366986456,"*",0.705076,"ERAP1","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005576//extracellular region;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane","GO:0004175//endopeptidase activity;GO:0005151//interleukin-1, Type II receptor binding;GO:0042277//peptide binding;GO:0008235//metalloexopeptidase activity;GO:0070006//metalloaminopeptidase activity;GO:0005138//interleukin-6 receptor binding;GO:0004177//aminopeptidase activity;GO:0008270//zinc ion binding","GO:0008217//regulation of blood pressure;GO:0006509//membrane protein ectodomain proteolysis;GO:0007165//signal transduction;GO:0001525//angiogenesis;GO:0007267//cell-cell signaling;GO:0045088//regulation of innate immune response;GO:0043171//peptide catabolic process;GO:0019885//antigen processing and presentation of endogenous peptide antigen via MHC class I;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0002250//adaptive immune response;GO:0045444//fat cell differentiation;GO:0045766//positive regulation of angiogenesis;GO:0009617//response to bacterium","K09604//adipocyte-derived leucine aminopeptidase [EC:3.4.11.-]","NP_001035548.1//endoplasmic reticulum aminopeptidase 1 isoform b precursor [Homo sapiens];NP_057526.3//endoplasmic reticulum aminopeptidase 1 isoform a precursor [Homo sapiens]","4;1//3;2//1"]
[7444,1804,21.62,21,-0.0419771951811654,0.612658560873216,"*",0.45679,"VRK2","GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0043234//protein complex;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005737//cytoplasm","GO:0004674//protein serine/threonine kinase activity;GO:0019904//protein domain specific binding;GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0019901//protein kinase binding","GO:0006468//protein phosphorylation;GO:0043408//regulation of MAPK cascade;GO:0016032//viral process;GO:0008360//regulation of cell shape;GO:2000659//regulation of interleukin-1-mediated signaling pathway;GO:0046777//protein autophosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0034599//cellular response to oxidative stress","K08816//vaccinia related kinase [EC:2.7.11.1]","NP_001123955.1//serine/threonine-protein kinase VRK2 isoform 3 [Homo sapiens];AAO73047.1//vaccinia related kinase 2 isoform 1 [Homo sapiens];NP_006287.2//serine/threonine-protein kinase VRK2 isoform 1 [Homo sapiens]","6;1//3;2//1"]
[140699,2043,2.1,2.04,-0.0418201756946271,1.02135751653878,"*",0.991626,"MROH8","NA","NA","NA","K04257//olfactory receptor;K14793//ribosomal RNA-processing protein 9","NP_998797.2//protein MROH8 isoform 3 [Homo sapiens];NP_998796.1//protein MROH8 isoform 2 [Homo sapiens];NP_689716.4//protein MROH8 isoform 1 [Homo sapiens]","2//1;5"]
[8533,1797,77.3,75.1,-0.0416555064105757,0.365849981599434,"*",0.226532,"COPS3","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0008180//COP9 signalosome;GO:0005737//cytoplasm","NA","GO:0043687//post-translational protein modification;GO:0000338//protein deneddylation;GO:0007165//signal transduction;GO:0000715//nucleotide-excision repair, DNA damage recognition;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0009416//response to light stimulus;GO:0001701//in utero embryonic development;GO:0006511//ubiquitin-dependent protein catabolic process","K12177//COP9 signalosome complex subunit 3","NP_001303286.1//COP9 signalosome complex subunit 3 isoform 6 [Homo sapiens];XP_010635702.1//PREDICTED: COP9 signalosome complex subunit 3 [Fukomys damarensis];NP_003644.2//COP9 signalosome complex subunit 3 isoform 1 [Homo sapiens];NP_001303284.1//COP9 signalosome complex subunit 3 isoform 4 [Homo sapiens];XP_014398312.1//PREDICTED: COP9 signalosome complex subunit 3 isoform X1 [Myotis brandtii]","1//3;3//A2MP1"]
[7693,4940,2.47,2.4,-0.041476635976159,0.89341872259192,"*",0.832064,"ZNF134","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_012509047.1//PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 134-like [Propithecus coquereli]",4]
[137682,2004,7.77,7.55,-0.0414379541952688,0.880812192292089,"*",0.815526,"NDUFAF6","GO:0005634//nucleus;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0005737//cytoplasm","GO:0016740//transferase activity","GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0009058//biosynthetic process","K18163//NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 6","NP_689629.2//NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 isoform 1 precursor [Homo sapiens];XP_022358167.1//NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 isoform X2 [Enhydra lutris kenyoni];NP_001341450.1//NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 isoform 5 [Homo sapiens];XP_020033822.1//NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 isoform X2 [Castor canadensis];NP_001341445.1//NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 isoform 3 [Homo sapiens];NP_001317511.1//NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 isoform 2 [Homo sapiens];XP_018887877.1//PREDICTED: NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 isoform X2 [Gorilla gorilla gorilla]","1//3;3//A2MP1"]
[440574,3755,8.83,8.58,-0.0414357901489203,0.767662375825438,"*",0.66953,"MINOS1","GO:0005739//mitochondrion;GO:0061617//MICOS complex","NA","NA","K17784//mitochondrial inner membrane organizing system protein 1","XP_021798671.1//MICOS complex subunit MIC10-like [Papio anubis];NP_001191012.1//MICOS complex subunit MIC10 isoform c [Homo sapiens]","1//3;3//A2MP1"]
[65056,4410,9.55,9.28,-0.0413759277955391,0.0862128105666575,"*",0.039431,"GPBP1","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0003677//DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated","NA","NP_001317966.1//vasculin isoform 5 [Homo sapiens];NP_001120708.1//vasculin isoform 2 [Homo sapiens];NP_001120707.2//vasculin isoform 3 [Homo sapiens];NP_075064.1//vasculin isoform 1 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[51112,2516,21.62,21.01,-0.0412903610616043,0.724569452630017,"*",0.611398,"TRAPPC12","GO:0005634//nucleus;GO:0005829//cytosol;GO:0000776//kinetochore;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0030008//TRAPP complex","GO:0004175//endopeptidase activity;GO:0017112//Rab guanyl-nucleotide exchange factor activity","GO:0090234//regulation of kinetochore assembly;GO:0051310//metaphase plate congression;GO:1905342//positive regulation of protein localization to kinetochore;GO:0007030//Golgi organization;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0051259//protein oligomerization;GO:0061024//membrane organization","K20309//trafficking protein particle complex subunit 12","NP_057114.5//trafficking protein particle complex subunit 12 [Homo sapiens];XP_018877022.1//PREDICTED: trafficking protein particle complex subunit 12 isoform X1 [Gorilla gorilla gorilla]","1//3;5"]
[4000,2759,187.15,181.87,-0.0412874624814786,0.740743393077425,"*",0.63905,"LMNA","GO:0005652//nuclear lamina;GO:0031012//extracellular matrix;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0005635//nuclear envelope;GO:0016607//nuclear speck;GO:0005882//intermediate filament;GO:0048471//perinuclear region of cytoplasm;GO:0005638//lamin filament;GO:0005829//cytosol","GO:0042802//identical protein binding;GO:0005198//structural molecule activity","GO:0007077//mitotic nuclear envelope disassembly;GO:0071456//cellular response to hypoxia;GO:0055015//ventricular cardiac muscle cell development;GO:1903243//negative regulation of cardiac muscle hypertrophy in response to stress;GO:0090201//negative regulation of release of cytochrome c from mitochondria;GO:0035105//sterol regulatory element binding protein import into nucleus;GO:0030334//regulation of cell migration;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:0036498//IRE1-mediated unfolded protein response;GO:0030951//establishment or maintenance of microtubule cytoskeleton polarity;GO:0032204//regulation of telomere maintenance;GO:0006998//nuclear envelope organization;GO:0008285//negative regulation of cell proliferation;GO:0072201//negative regulation of mesenchymal cell proliferation;GO:0007517//muscle organ development;GO:1900180//regulation of protein localization to nucleus;GO:0007084//mitotic nuclear envelope reassembly;GO:0034613//cellular protein localization;GO:0090343//positive regulation of cell aging;GO:0034504//protein localization to nucleus","K12641//lamin A/C","EAW52998.1//lamin A/C, isoform CRA_c [Homo sapiens];EAW52996.1//lamin A/C, isoform CRA_a [Homo sapiens];NP_001269553.1//lamin isoform E [Homo sapiens];NP_001244303.1//lamin isoform D [Homo sapiens];EAW53000.1//lamin A/C, isoform CRA_d [Homo sapiens]","1//3;3//A2MP1;2//1"]
[22820,3114,38.99,37.89,-0.0412870148889275,0.621021469107934,"*",0.465008,"COPG1","GO:0070382//exocytic vesicle;GO:0030126//COPI vesicle coat;GO:0030133//transport vesicle;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005789//endoplasmic reticulum membrane;GO:0000139//Golgi membrane","GO:0005198//structural molecule activity","GO:0072384//organelle transport along microtubule;GO:0006886//intracellular protein transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0051683//establishment of Golgi localization;GO:0016192//vesicle-mediated transport","K17267//coatomer subunit gamma","NP_057212.1//coatomer subunit gamma-1 [Homo sapiens]","3//A2MP1"]
[100130771,1181,4.97,4.83,-0.041222662726513,0.930015894471696,"*",0.878316,"EFCAB10","NA","GO:0005509//calcium ion binding","NA","K20474//RAD50-interacting protein 1","EAW83369.1//hCG1779729, isoform CRA_b [Homo sapiens];XP_007980695.1//PREDICTED: EF-hand calcium-binding domain-containing protein 10 [Chlorocebus sabaeus];NP_001342459.1//eF-hand calcium-binding domain-containing protein 10 isoform 4 [Homo sapiens]","1//3"]
[8560,2102,61.2,59.49,-0.0408844746300101,0.612294634531407,"*",0.456442,"DEGS1","GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0005887//integral component of plasma membrane;GO:0035579//specific granule membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005739//mitochondrion;GO:0005886//plasma membrane","GO:0042284//sphingolipid delta-4 desaturase activity;GO:0009055//electron transfer activity","GO:0006636//unsaturated fatty acid biosynthetic process;GO:0030148//sphingolipid biosynthetic process;GO:0043312//neutrophil degranulation;GO:0006633//fatty acid biosynthetic process;GO:0046513//ceramide biosynthetic process","K04712//sphingolipid 4-desaturase/C4-monooxygenase [EC:1.14.19.17 1.14.18.5]","NP_001308470.1//sphingolipid delta(4)-desaturase DES1 isoform 2 [Homo sapiens];NP_003667.1//sphingolipid delta(4)-desaturase DES1 isoform 1 [Homo sapiens];XP_017804685.1//sphingolipid delta(4)-desaturase DES1 isoform X1 [Papio anubis]","1//3;3//A2MP1"]
[10213,1734,48.76,47.4,-0.0408110668345906,0.671306196686427,"*",0.552964,"PSMD14","GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0008541//proteasome regulatory particle, lid subcomplex;GO:0000502//proteasome complex;GO:0022624//proteasome accessory complex;GO:0031597//cytosolic proteasome complex;GO:0005829//cytosol;GO:0005576//extracellular region;GO:1904813//ficolin-1-rich granule lumen","GO:0004175//endopeptidase activity;GO:0061578//Lys63-specific deubiquitinase activity;GO:0046872//metal ion binding;GO:0008237//metallopeptidase activity;GO:0061133//endopeptidase activator activity;GO:0036459//thiol-dependent ubiquitinyl hydrolase activity;GO:0070628//proteasome binding","GO:0043687//post-translational protein modification;GO:0038061//NIK/NF-kappaB signaling;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0006521//regulation of cellular amino acid metabolic process;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle;GO:0045471//response to ethanol;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0016579//protein deubiquitination;GO:0043312//neutrophil degranulation;GO:0043488//regulation of mRNA stability;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0000209//protein polyubiquitination;GO:0070536//protein K63-linked deubiquitination;GO:0055085//transmembrane transport;GO:0000165//MAPK cascade;GO:0050852//T cell receptor signaling pathway;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0061136//regulation of proteasomal protein catabolic process;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:1902036//regulation of hematopoietic stem cell differentiation;GO:0000724//double-strand break repair via homologous recombination;GO:0006303//double-strand break repair via nonhomologous end joining","K03030//26S proteasome regulatory subunit N11","XP_020860546.1//26S proteasome non-ATPase regulatory subunit 14 isoform X1 [Phascolarctos cinereus]",5]
[23231,4438,11.49,11.17,-0.0407496121627985,0.628961786431965,"*",0.505524,"SEL1L3","GO:0016021//integral component of membrane","NA","NA","K11653//AT-rich interactive domain-containing protein 1;K05746//enabled;K14026//SEL1 protein;K12891//splicing factor, arginine/serine-rich 2;K07432//beta-1,4-N-acetylglucosaminyltransferase [EC:2.4.1.141]","NP_001284521.1//protein sel-1 homolog 3 isoform 2 [Homo sapiens];XP_016806909.1//PREDICTED: protein sel-1 homolog 3 isoform X1 [Pan troglodytes];NP_056002.2//protein sel-1 homolog 3 isoform 1 [Homo sapiens]","4;1//3"]
[112939,4518,53.89,52.39,-0.0407261247206872,0.459069781160093,"*",0.309658,"NACC1","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0030054//cell junction;GO:0005737//cytoplasm","NA","GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0051260//protein homooligomerization;GO:0008284//positive regulation of cell proliferation","K10486//BTB/POZ domain-containing protein 14","XP_002828800.2//PREDICTED: nucleus accumbens-associated protein 1 [Pongo abelii]","3//A2MP1"]
[976,3290,18.33,17.82,-0.0407094490179636,0.706753087674714,"*",0.59194,"ADGRE5","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0030667//secretory granule membrane;GO:0005887//integral component of plasma membrane;GO:0005925//focal adhesion;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005509//calcium ion binding;GO:0004888//transmembrane signaling receptor activity;GO:0004930//G-protein coupled receptor activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0007166//cell surface receptor signaling pathway;GO:0006954//inflammatory response;GO:0007155//cell adhesion;GO:0006928//movement of cell or subcellular component;GO:0006955//immune response;GO:0043312//neutrophil degranulation","K08446//CD97 antigen","XP_011949537.1//PREDICTED: CD97 antigen isoform X1 [Cercocebus atys];XP_011949539.1//PREDICTED: CD97 antigen isoform X3 [Cercocebus atys];XP_011949542.1//PREDICTED: CD97 antigen isoform X5 [Cercocebus atys]","4;3//A2MP1;2//1"]
[651,5828,0.36,0.35,-0.0406419844973459,1.02139508404604,"*",0.994348,"BMP3","GO:0070062//extracellular exosome;GO:0005615//extracellular space","GO:0008083//growth factor activity;GO:0005125//cytokine activity;GO:0005102//receptor binding;GO:0005160//transforming growth factor beta receptor binding;GO:0070700//BMP receptor binding","GO:0001649//osteoblast differentiation;GO:0007267//cell-cell signaling;GO:0043408//regulation of MAPK cascade;GO:0051216//cartilage development;GO:0030509//BMP signaling pathway;GO:0060395//SMAD protein signal transduction;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0001501//skeletal system development;GO:0048468//cell development;GO:0042981//regulation of apoptotic process","K05496//bone morphogenetic protein 3/3B","NP_001192.3//bone morphogenetic protein 3 preproprotein [Homo sapiens]","3//A2MP1"]
[11146,2041,2.52,2.45,-0.0406419844973458,0.921532977198697,"*",0.867824,"GLMN","GO:0031462//Cul2-RING ubiquitin ligase complex;GO:0031464//Cul4A-RING E3 ubiquitin ligase complex;GO:0005622//intracellular;GO:0005737//cytoplasm;GO:0031463//Cul3-RING ubiquitin ligase complex;GO:0031461//cullin-RING ubiquitin ligase complex","GO:0055105//ubiquitin-protein transferase inhibitor activity;GO:0005171//hepatocyte growth factor receptor binding;GO:0031625//ubiquitin protein ligase binding","GO:0032434//regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0040029//regulation of gene expression, epigenetic;GO:0045086//positive regulation of interleukin-2 biosynthetic process;GO:0042692//muscle cell differentiation;GO:0042130//negative regulation of T cell proliferation;GO:0042327//positive regulation of phosphorylation;GO:0001843//neural tube closure;GO:0050715//positive regulation of cytokine secretion;GO:0001570//vasculogenesis","K18587//ubiquinone biosynthesis protein COQ9","XP_016855626.1//PREDICTED: glomulin isoform X1 [Homo sapiens];XP_016855627.1//PREDICTED: glomulin isoform X2 [Homo sapiens]","1//3;2//1"]
[51324,1708,107.8,104.82,-0.0404431640019522,0.231216431480858,"*",0.1289248,"SPG21","GO:0043231//intracellular membrane-bounded organelle;GO:0010008//endosome membrane;GO:0030140//trans-Golgi network transport vesicle;GO:0005829//cytosol","GO:0042609//CD4 receptor binding","GO:0050851//antigen receptor-mediated signaling pathway","K19367//maspardin","NP_057714.1//maspardin isoform a [Homo sapiens];XP_014997952.1//PREDICTED: maspardin isoform X1 [Macaca mulatta]","6;4"]
[6687,3050,22.46,21.84,-0.0403850714807488,0.702528266866342,"*",0.587346,"SPG7","GO:0005757//mitochondrial permeability transition pore complex;GO:1904115//axon cytoplasm;GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0005745//m-AAA complex","GO:0008233//peptidase activity;GO:0004222//metalloendopeptidase activity;GO:0005524//ATP binding;GO:0051082//unfolded protein binding;GO:0008270//zinc ion binding","GO:0007399//nervous system development;GO:0006851//mitochondrial calcium ion transmembrane transport;GO:0006508//proteolysis;GO:0046902//regulation of mitochondrial membrane permeability;GO:0008089//anterograde axonal transport;GO:1902686//mitochondrial outer membrane permeabilization involved in programmed cell death","K09552//spastic paraplegia 7 [EC:3.4.24.-]","NP_003110.1//paraplegin isoform 1 precursor [Homo sapiens];NP_955399.1//paraplegin isoform 2 precursor [Homo sapiens]","3//A2MP1;2//1"]
[3615,1712,112.23,109.14,-0.04027842289934,0.531723079334331,"*",0.378038,"IMPDH2","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0000166//nucleotide binding;GO:0003938//IMP dehydrogenase activity","GO:0006177//GMP biosynthetic process","K00088//IMP dehydrogenase [EC:1.1.1.205]","XP_020651049.1//inosine-5'-monophosphate dehydrogenase 2 isoform X2 [Pogona vitticeps]","2//1"]
[57035,1525,4,3.89,-0.0402298447885327,0.78841663866497,"*",0.697996,"RSRP1","NA","NA","NA","K15176//RNA polymerase-associated protein CTR9;K15174//RNA polymerase II-associated factor 1","NP_064713.3//arginine/serine-rich protein 1 [Homo sapiens];BAX25201.1//arginine/serine-rich protein 1 [Pan troglodytes]","4;1//3"]
[8772,1855,27.28,26.53,-0.0402189687954766,0.754397758232236,"*",0.653994,"FADD","NA","NA","NA","K02373//FAS-associated death domain protein","XP_011896682.1//PREDICTED: FAS-associated death domain protein [Cercocebus atys]","3//A2MP1"]
[51187,1487,73.85,71.82,-0.0402122679874935,0.628424935230542,"*",0.505958,"RSL24D1","GO:0005840//ribosome;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0022625//cytosolic large ribosomal subunit","GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome","GO:0042254//ribosome biogenesis;GO:1902626//assembly of large subunit precursor of preribosome;GO:0006412//translation;GO:0000027//ribosomal large subunit assembly","K02896//large subunit ribosomal protein L24e","XP_019824362.1//PREDICTED: probable ribosome biogenesis protein RLP24 [Bos indicus]","2//1"]
[493856,5892,10.92,10.62,-0.0401890901156989,0.723278155558854,"*",0.610082,"CISD2","NA","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K16603//tubulin polyglutamylase TTLL9 [EC:6.-.-.-];K04460//serine/threonine-protein phosphatase 5 [EC:3.1.3.16]","XP_003257613.1//PREDICTED: CDGSH iron-sulfur domain-containing protein 2 [Nomascus leucogenys]",4]
[54475,2627,12.49,12.15,-0.0398171631148141,0.785370042637581,"*",0.694168,"NLE1","GO:0005840//ribosome;GO:0005634//nucleus;GO:0005730//nucleolus","NA","GO:0045930//negative regulation of mitotic cell cycle;GO:0001822//kidney development;GO:0000027//ribosomal large subunit assembly;GO:2001268//negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0001826//inner cell mass cell differentiation;GO:0061484//hematopoietic stem cell homeostasis;GO:0001756//somitogenesis;GO:0007219//Notch signaling pathway;GO:0048705//skeletal system morphogenesis","K14855//ribosome assembly protein 4","XP_017746378.1//PREDICTED: notchless protein homolog 1 isoform X1 [Rhinopithecus bieti];EAW80167.1//notchless homolog 1 (Drosophila), isoform CRA_c, partial [Homo sapiens]","4;2//1"]
[54470,1796,21.68,21.09,-0.0398056615601801,0.640597473716712,"*",0.519528,"ARMCX6","GO:0016021//integral component of membrane;GO:0005741//mitochondrial outer membrane","NA","NA","NA","XP_011529278.1//PREDICTED: protein ARMCX6 isoform X1 [Homo sapiens]","1//3;3//A2MP1"]
[10139,2504,9.57,9.31,-0.0397377569272318,0.911952547904991,"*",0.855662,"ARFRP1","GO:0016020//membrane;GO:0032588//trans-Golgi network membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005802//trans-Golgi network","GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0007369//gastrulation;GO:0007165//signal transduction;GO:0034067//protein localization to Golgi apparatus;GO:0043001//Golgi to plasma membrane protein transport;GO:0007264//small GTPase mediated signal transduction;GO:0042147//retrograde transport, endosome to Golgi","K07952//ADP-ribosylation factor related protein 1","XP_008008901.1//PREDICTED: ADP-ribosylation factor-related protein 1 isoform X1 [Chlorocebus sabaeus];EAW75230.1//ADP-ribosylation factor related protein 1, isoform CRA_a [Homo sapiens];XP_009435924.1//PREDICTED: ADP-ribosylation factor-related protein 1 isoform X1 [Pan troglodytes];XP_020016627.1//ADP-ribosylation factor-related protein 1 isoform X1 [Castor canadensis];NP_003215.1//ADP-ribosylation factor-related protein 1 isoform a [Homo sapiens];XP_017827664.1//PREDICTED: ADP-ribosylation factor-related protein 1 isoform X4 [Callithrix jacchus]","3//A2MP1;2//1;5"]
[51097,2482,22.86,22.24,-0.0396686154909709,0.739310349473684,"*",0.637536,"SCCPDH","NA","NA","NA","K17581//consortin;K13171//serine/arginine repetitive matrix protein 1;K02184//formin 2","XP_011727835.1//PREDICTED: saccharopine dehydrogenase-like oxidoreductase [Macaca nemestrina]","2//1"]
[399979,5028,6.64,6.46,-0.0396490766529999,0.093694700243309,"*",0.0433926,"SNX19","GO:0031901//early endosome membrane;GO:0005737//cytoplasm;GO:0030659//cytoplasmic vesicle membrane","GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0035091//phosphatidylinositol binding","GO:0002062//chondrocyte differentiation;GO:1990502//dense core granule maturation;GO:0030073//insulin secretion;GO:0006887//exocytosis","K17930//sorting nexin-19","NP_001334854.1//sorting nexin-19 isoform 10 [Homo sapiens];NP_055573.2//sorting nexin-19 isoform 1 [Homo sapiens];XP_011825428.1//PREDICTED: sorting nexin-19 isoform X3 [Mandrillus leucophaeus];NP_001334847.1//sorting nexin-19 isoform 3 [Homo sapiens];NP_001334850.1//sorting nexin-19 isoform 6 [Homo sapiens];NP_001334851.1//sorting nexin-19 isoform 7 [Homo sapiens];NP_001334848.1//sorting nexin-19 isoform 4 [Homo sapiens];NP_001334852.1//sorting nexin-19 isoform 8 [Homo sapiens];NP_001334849.1//sorting nexin-19 isoform 5 [Homo sapiens]","1//3;2//1"]
[3065,2091,42.53,41.38,-0.0395472097657541,0.669586449395483,"*",0.551254,"HDAC1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000785//chromatin;GO:0016580//Sin3 complex;GO:0000790//nuclear chromatin;GO:0005737//cytoplasm;GO:0016581//NuRD complex;GO:0043234//protein complex;GO:0005829//cytosol;GO:0000118//histone deacetylase complex","GO:0047485//protein N-terminus binding;GO:0001103//RNA polymerase II repressing transcription factor binding;GO:0032041//NAD-dependent histone deacetylase activity (H3-K14 specific);GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0033613//activating transcription factor binding;GO:0001047//core promoter binding;GO:0004407//histone deacetylase activity;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0001046//core promoter sequence-specific DNA binding;GO:0042826//histone deacetylase binding;GO:0002039//p53 binding;GO:0033558//protein deacetylase activity;GO:0070491//repressing transcription factor binding;GO:0044212//transcription regulatory region DNA binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0001106//RNA polymerase II transcription corepressor activity;GO:0046872//metal ion binding;GO:0051059//NF-kappaB binding;GO:0019213//deacetylase activity;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0008134//transcription factor binding;GO:0019899//enzyme binding;GO:0031492//nucleosomal DNA binding","GO:0006338//chromatin remodeling;GO:0007596//blood coagulation;GO:0061198//fungiform papilla formation;GO:0060789//hair follicle placode formation;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0060766//negative regulation of androgen receptor signaling pathway;GO:0043922//negative regulation by host of viral transcription;GO:0045892//negative regulation of transcription, DNA-templated;GO:0009913//epidermal cell differentiation;GO:0070933//histone H4 deacetylation;GO:0043066//negative regulation of apoptotic process;GO:0016032//viral process;GO:0042475//odontogenesis of dentin-containing tooth;GO:1901796//regulation of signal transduction by p53 class mediator;GO:1904837//beta-catenin-TCF complex assembly;GO:0006346//methylation-dependent chromatin silencing;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0010870//positive regulation of receptor biosynthetic process;GO:0016575//histone deacetylation;GO:0006476//protein deacetylation;GO:0006355//regulation of transcription, DNA-templated;GO:0010629//negative regulation of gene expression;GO:0042733//embryonic digit morphogenesis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0043044//ATP-dependent chromatin remodeling;GO:0032922//circadian regulation of gene expression;GO:0061029//eyelid development in camera-type eye;GO:0006351//transcription, DNA-templated;GO:0045652//regulation of megakaryocyte differentiation;GO:0006325//chromatin organization;GO:0070932//histone H3 deacetylation;GO:0008284//positive regulation of cell proliferation","K06067//histone deacetylase 1/2 [EC:3.5.1.98]","NP_004955.2//histone deacetylase 1 [Homo sapiens]","2//1"]
[3183,3226,256.41,249.48,-0.0395283641866377,0.141312864294663,"*",0.0706122,"HNRNPC","GO:0030529//intracellular ribonucleoprotein complex;GO:0019013//viral nucleocapsid","GO:0003723//RNA binding","NA","K12884//heterogeneous nuclear ribonucleoprotein C1/C2","BAD92764.1//Heterogeneous nuclear ribonucleoproteins C1/C2 variant, partial [Homo sapiens];XP_863431.2//heterogeneous nuclear ribonucleoproteins C1/C2 isoform X4 [Canis lupus familiaris]","1//3;3//A2MP1;2//1"]
[440138,2595,1.11,1.08,-0.0395283641866375,1.02186902021893,"*",0.993466,"ALG11","GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0004377//GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity","GO:0006490//oligosaccharide-lipid intermediate biosynthetic process;GO:0033577//protein glycosylation in endoplasmic reticulum","K03844//alpha-1,2-mannosyltransferase [EC:2.4.1.131]","NP_001004127.2//GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase [Homo sapiens]","2//1"]
[144453,2258,0.74,0.72,-0.0395283641866375,0.833926641436464,"*",0.755932,"BEST3","GO:0034707//chloride channel complex;GO:0005886//plasma membrane","GO:0005254//chloride channel activity","GO:0043271//negative regulation of ion transport","K13880//bestrophin-3","NP_116124.2//bestrophin-3 isoform 1 [Homo sapiens];NP_001269543.1//bestrophin-3 isoform 4 [Homo sapiens];NP_689652.2//bestrophin-3 isoform 2 [Homo sapiens];XP_016874354.1//PREDICTED: bestrophin-3 isoform X5 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[26354,2013,48.91,47.59,-0.0394710101772974,0.6536895752552,"*",0.533174,"GNL3","GO:0016020//membrane;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0005730//nucleolus;GO:0016604//nuclear body","GO:0003723//RNA binding;GO:0048027//mRNA 5'-UTR binding;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:1902895//positive regulation of pri-miRNA transcription from RNA polymerase II promoter;GO:0042127//regulation of cell proliferation;GO:0033235//positive regulation of protein sumoylation;GO:0032206//positive regulation of telomere maintenance;GO:0042254//ribosome biogenesis;GO:0008283//cell proliferation;GO:0019827//stem cell population maintenance;GO:0017145//stem cell division;GO:1904816//positive regulation of protein localization to chromosome, telomeric region","K14538//nuclear GTP-binding protein","EAW65249.1//guanine nucleotide binding protein-like 3 (nucleolar), isoform CRA_a [Homo sapiens];NP_055181.3//guanine nucleotide-binding protein-like 3 isoform 1 [Homo sapiens]","1//3;4"]
[100129361,4840,5.56,5.41,-0.0394562888966923,0.827516971998891,"*",0.747428,"SMIM10L1","NA","NA","NA","NA","DAA29354.1//TPA: hypothetical protein BOS_5846 [Bos taurus]","1//3"]
[84950,2780,7.43,7.23,-0.0393665635874783,0.847622086539121,"*",0.773812,"PRPF38A","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0005681//spliceosomal complex;GO:0071011//precatalytic spliceosome","GO:0003723//RNA binding","GO:0006397//mRNA processing;GO:0000398//mRNA splicing, via spliceosome;GO:0008380//RNA splicing","K12849//pre-mRNA-splicing factor 38A","NP_116253.2//pre-mRNA-splicing factor 38A [Homo sapiens]","3//A2MP1"]
[9654,4997,11.16,10.86,-0.0393129240248262,0.737803256806796,"*",0.636144,"TTLL4","GO:0005929//cilium;GO:0005874//microtubule;GO:0005829//cytosol","GO:0015631//tubulin binding;GO:0070739//protein-glutamic acid ligase activity;GO:0070740//tubulin-glutamic acid ligase activity;GO:0005524//ATP binding","GO:0018200//peptidyl-glutamic acid modification;GO:0018095//protein polyglutamylation","K16601//tubulin polyglutamylase TTLL4 [EC:6.-.-.-]","NP_055455.3//tubulin polyglutamylase TTLL4 [Homo sapiens]",4]
[8614,5361,20.46,19.91,-0.0393129240248262,0.632936509485095,"*",0.51173,"STC2","GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005576//extracellular region;GO:0048471//perinuclear region of cytoplasm","GO:0020037//heme binding;GO:0042803//protein homodimerization activity;GO:0019899//enzyme binding;GO:0005179//hormone activity","GO:0043687//post-translational protein modification;GO:0071456//cellular response to hypoxia;GO:0046697//decidualization;GO:0046885//regulation of hormone biosynthetic process;GO:0043434//response to peptide hormone;GO:0010629//negative regulation of gene expression;GO:0033280//response to vitamin D;GO:0007566//embryo implantation;GO:0006979//response to oxidative stress;GO:0044267//cellular protein metabolic process;GO:2001256//regulation of store-operated calcium entry;GO:0040015//negative regulation of multicellular organism growth;GO:0006874//cellular calcium ion homeostasis;GO:0030968//endoplasmic reticulum unfolded protein response","NA","NP_003705.1//stanniocalcin-2 precursor [Homo sapiens]","2//1"]
[84680,2196,6.71,6.53,-0.0392297746537527,0.874138670822605,"*",0.807596,"ACCS","NA","GO:0042802//identical protein binding;GO:0003824//catalytic activity;GO:0030170//pyridoxal phosphate binding;GO:0042803//protein homodimerization activity","GO:0009058//biosynthetic process","K00816//kynurenine---oxoglutarate transaminase / cysteine-S-conjugate beta-lyase / glutamine---phenylpyruvate transaminase [EC:2.6.1.7 4.4.1.13 2.6.1.64];K00815//tyrosine aminotransferase [EC:2.6.1.5];K00814//alanine transaminase [EC:2.6.1.2]","XP_005253227.2//PREDICTED: 1-aminocyclopropane-1-carboxylate synthase-like protein 1 isoform X1 [Homo sapiens]","1//3;3//A2MP1"]
[3336,965,228.54,222.43,-0.0390953106539907,0.520377616595136,"*",0.364336,"HSPE1","NA","NA","NA","K04078//chaperonin GroES","XP_019694695.1//PREDICTED: 10 kDa heat shock protein, mitochondrial [Felis catus]","2//1"]
[64780,3478,5.62,5.47,-0.0390292974283697,0.765510877782565,"*",0.667366,"MICAL1","GO:0005829//cytosol;GO:0005882//intermediate filament;GO:1990026//hippocampal mossy fiber expansion;GO:0005737//cytoplasm;GO:0030496//midbody","GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen;GO:0019901//protein kinase binding;GO:0003779//actin binding;GO:0046872//metal ion binding;GO:0004497//monooxygenase activity;GO:0017124//SH3 domain binding;GO:0017137//Rab GTPase binding;GO:0071949//FAD binding","GO:0019417//sulfur oxidation;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007165//signal transduction;GO:0007596//blood coagulation;GO:0055114//oxidation-reduction process;GO:0001933//negative regulation of protein phosphorylation;GO:0007010//cytoskeleton organization;GO:1903305//regulation of regulated secretory pathway;GO:0030042//actin filament depolymerization","K19947//F-actin monooxygenase [EC:1.14.13.225]","NP_001273542.1//[F-actin]-methionine sulfoxide oxidase MICAL1 isoform 3 [Homo sapiens];NP_001152763.1//[F-actin]-methionine sulfoxide oxidase MICAL1 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[116028,1451,23.24,22.62,-0.0390111394147082,0.809682054904163,"*",0.721942,"RMI2","GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck","GO:0003677//DNA binding","GO:1901796//regulation of signal transduction by p53 class mediator;GO:0000732//strand displacement;GO:0033045//regulation of sister chromatid segregation;GO:0000731//DNA synthesis involved in DNA repair;GO:0006260//DNA replication","K15365//RecQ-mediated genome instability protein 2","NP_689521.1//recQ-mediated genome instability protein 2 [Homo sapiens]","2//1"]
[26528,2221,113.43,110.41,-0.038931410062299,0.487274680273349,"*",0.334784,"DAZAP1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:1990904//ribonucleoprotein complex;GO:0043234//protein complex;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0035613//RNA stem-loop binding;GO:0008266//poly(U) RNA binding;GO:0034046//poly(G) binding","GO:0048026//positive regulation of mRNA splicing, via spliceosome;GO:0008283//cell proliferation;GO:0030154//cell differentiation;GO:0007283//spermatogenesis;GO:0001893//maternal placenta development","K14411//RNA-binding protein Musashi","NP_001338962.1//DAZ-associated protein 1 isoform c [Homo sapiens];NP_001338964.1//DAZ-associated protein 1 isoform e [Homo sapiens];NP_061832.2//DAZ-associated protein 1 isoform b [Homo sapiens];XP_014322693.1//PREDICTED: DAZ-associated protein 1 isoform X3 [Myotis lucifugus];NP_733829.1//DAZ-associated protein 1 isoform a [Homo sapiens]","1//3;3//A2MP1;2//1"]
[9812,4627,14.7,14.31,-0.0387924829970588,0.655438932330827,"*",0.534806,"KIAA0141","GO:0005739//mitochondrion","NA","GO:0043281//regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors","K14026//SEL1 protein","NP_055588.3//death ligand signal enhancer precursor [Homo sapiens]","4;2//1"]
[144404,7510,22.26,21.67,-0.0387544392482859,0.578549186507596,"*",0.421978,"TMEM120B","GO:0005637//nuclear inner membrane;GO:0016021//integral component of membrane","NA","GO:0051291//protein heterooligomerization;GO:0045444//fat cell differentiation","K14574//ribosome maturation protein SDO1;K12025//tripartite motif-containing protein 52","NP_001074294.2//transmembrane protein 120B [Homo sapiens]","2//1"]
[6727,1140,102.7,99.98,-0.0387247495220344,0.651955662710188,"*",0.49515,"SRP14","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005786//signal recognition particle, endoplasmic reticulum targeting","GO:0050825//ice binding;GO:0030942//endoplasmic reticulum signal peptide binding;GO:0008312//7S RNA binding","GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0042493//response to drug","K03104//signal recognition particle subunit SRP14","NP_001125409.1//signal recognition particle 14 kDa protein [Pongo abelii];NP_001296363.1//signal recognition particle 14 kDa protein isoform 2 [Homo sapiens]","1//3;5"]
[51493,2081,32.18,31.33,-0.0386195563523926,0.728306462769504,"*",0.615372,"RTCB","GO:0043231//intracellular membrane-bounded organelle;GO:0072669//tRNA-splicing ligase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005789//endoplasmic reticulum membrane","GO:0003723//RNA binding;GO:0046872//metal ion binding;GO:0005524//ATP binding;GO:0017166//vinculin binding;GO:0003972//RNA ligase (ATP) activity","GO:0006388//tRNA splicing, via endonucleolytic cleavage and ligation","K14415//tRNA-splicing ligase RtcB [EC:6.5.1.3]","EPY77446.1//tRNA-splicing ligase RtcB-like protein [Camelus ferus]",4]
[399909,6584,25.38,24.71,-0.0385970585123215,0.578844064959615,"*",0.421722,"PCNX3","GO:0016021//integral component of membrane","NA","NA","K22016//mucin-3/17","NP_115599.2//pecanex-like protein 3 [Homo sapiens]","3//A2MP1"]
[63943,1357,4.55,4.43,-0.0385598465310403,0.931363773714891,"*",0.880172,"FKBPL","GO:0005829//cytosol","NA","GO:0009314//response to radiation;GO:0050821//protein stabilization","K20097//FK506-binding protein-like","XP_007971213.1//PREDICTED: FK506-binding protein-like isoform X1 [Chlorocebus sabaeus]","3//A2MP1"]
[79037,1587,15.58,15.17,-0.0384741478146357,0.839139170097061,"*",0.763126,"PVRIG","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004872//receptor activity;GO:0019902//phosphatase binding","GO:0050860//negative regulation of T cell receptor signaling pathway","K13055//cohesin complex subunit SA-3","NP_076975.2//transmembrane protein PVRIG [Homo sapiens]","3//A2MP1"]
[55379,2933,120.95,117.78,-0.0383161906799601,0.391133778772254,"*",0.251688,"LRRC59","NA","NA","NA","K19613//leucine-rich repeat protein SHOC2","XP_017827410.1//PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein LOC100387424 [Callithrix jacchus]","3//A2MP1"]
[4595,1821,7.25,7.06,-0.0383128116311165,0.795906436781609,"*",0.70657,"MUTYH","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion","GO:0032407//MutSalpha complex binding;GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0016787//hydrolase activity;GO:0019104//DNA N-glycosylase activity;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0000701//purine-specific mismatch base pair DNA N-glycosylase activity","GO:0045007//depurination;GO:0006284//base-excision repair;GO:0006281//DNA repair;GO:0006298//mismatch repair","K03575//A/G-specific adenine glycosylase [EC:3.2.2.-]","NP_001337579.1//adenine DNA glycosylase isoform 9 [Homo sapiens];NP_001121897.1//adenine DNA glycosylase isoform 5 [Homo sapiens];NP_036354.1//adenine DNA glycosylase isoform 1 [Homo sapiens];NP_001041638.1//adenine DNA glycosylase isoform 4 [Homo sapiens];NP_001041636.1//adenine DNA glycosylase isoform 2 [Homo sapiens];XP_018873066.1//PREDICTED: adenine DNA glycosylase isoform X8 [Gorilla gorilla gorilla];NP_001280119.1//adenine DNA glycosylase isoform 6 [Homo sapiens]","1//3;2//1"]
[573,3885,13.37,13.02,-0.0382700169277173,0.760521104967603,"*",0.661302,"BAG1","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0005057//signal transducer activity, downstream of receptor;GO:0051087//chaperone binding;GO:0000774//adenyl-nucleotide exchange factor activity","GO:1900034//regulation of cellular response to heat;GO:0043066//negative regulation of apoptotic process;GO:0007166//cell surface receptor signaling pathway;GO:0006915//apoptotic process","K09555//BCL2-associated athanogene 1","BAD96469.1//BCL2-associated athanogene isoform 1L variant, partial [Homo sapiens]","1//3;5"]
[1627,2942,49.32,48.03,-0.0382369911654259,0.634676039521754,"*",0.47853,"DBN1","GO:0030425//dendrite;GO:0005921//gap junction;GO:0005622//intracellular;GO:0005737//cytoplasm;GO:0030863//cortical cytoskeleton;GO:0030426//growth cone;GO:0015629//actin cytoskeleton;GO:0042641//actomyosin;GO:0005886//plasma membrane","GO:0003779//actin binding;GO:0005522//profilin binding;GO:0045296//cadherin binding","GO:0050773//regulation of dendrite development;GO:0061351//neural precursor cell proliferation;GO:0010644//cell communication by electrical coupling;GO:0007015//actin filament organization;GO:0048168//regulation of neuronal synaptic plasticity;GO:0032507//maintenance of protein location in cell;GO:0010643//cell communication by chemical coupling","K20520//drebrin-like protein","NP_004386.2//drebrin isoform a [Homo sapiens];NP_543157.1//drebrin isoform b [Homo sapiens]","3//A2MP1;2//1"]
[57062,2967,50.59,49.27,-0.0381427674950869,0.612603972800537,"*",0.456826,"DDX24","GO:0016020//membrane;GO:0005730//nucleolus;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0004004//ATP-dependent RNA helicase activity;GO:0005524//ATP binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity","GO:0016070//RNA metabolic process;GO:0010501//RNA secondary structure unwinding","K14805//ATP-dependent RNA helicase DDX24/MAK5 [EC:3.6.4.13]","NP_065147.1//ATP-dependent RNA helicase DDX24 [Homo sapiens]","3//A2MP1"]
[114987,4868,3.86,3.76,-0.037868185590443,0.866435580178098,"*",0.79793,"WDR31","NA","NA","NA","K12025//tripartite motif-containing protein 52","NP_660284.1//WD repeat-containing protein 31 isoform 3 [Homo sapiens];NP_001012361.1//WD repeat-containing protein 31 isoform 1 [Homo sapiens];XP_015981769.1//PREDICTED: WD repeat-containing protein 31 isoform X3 [Rousettus aegyptiacus]","4;3//A2MP1;2//1"]
[91869,5112,9.67,9.42,-0.0377888298640581,0.753278589323124,"*",0.652788,"RFT1","GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0005319//lipid transporter activity","GO:0034203//glycolipid translocation;GO:0008643//carbohydrate transport","K06316//oligosaccharide translocation protein RFT1","NP_443091.1//protein RFT1 homolog [Homo sapiens]","3//A2MP1"]
[54537,3598,12,11.69,-0.0377594759642246,0.626287916101364,"*",0.502826,"FAM35A","NA","NA","NA","NA","NP_001317041.1//protein FAM35A isoform 1 [Homo sapiens];NP_061927.2//protein FAM35A isoform 2 [Homo sapiens]","1//3;2//1"]
[165631,4180,15.49,15.09,-0.0377443382628853,0.747173877090119,"*",0.646188,"PARP15","GO:0005634//nucleus","GO:0070403//NAD+ binding;GO:0001191//transcriptional repressor activity, RNA polymerase II transcription factor binding;GO:0003950//NAD+ ADP-ribosyltransferase activity","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0070212//protein poly-ADP-ribosylation","K15261//poly [ADP-ribose] polymerase 10/14/15 [EC:2.4.2.30]","NP_001295250.1//poly [ADP-ribose] polymerase 15 isoform 4 precursor [Homo sapiens];NP_001106995.1//poly [ADP-ribose] polymerase 15 isoform 1 [Homo sapiens];NP_001295249.1//poly [ADP-ribose] polymerase 15 isoform 3 [Homo sapiens];NP_689828.1//poly [ADP-ribose] polymerase 15 isoform 2 precursor [Homo sapiens]","1//3;2//1"]
[339210,2074,1.55,1.51,-0.0377196659491588,0.959468490217889,"*",0.917964,"C17orf67","GO:0005576//extracellular region","NA","NA","NA","Q0P5P2.2//RecName: Full=Uncharacterized protein C17orf67; Flags: Precursor","3//A2MP1"]
[10541,1617,176.42,171.89,-0.0375285065280672,0.469217121223287,"*",0.318882,"ANP32B","NA","NA","NA","K18647//acidic leucine-rich nuclear phosphoprotein 32 family member B","XP_016376038.1//PREDICTED: acidic leucine-rich nuclear phosphoprotein 32 family member B isoform X1 [Sinocyclocheilus rhinocerous]","2//1"]
[643699,5329,0.39,0.38,-0.0374747054186629,0.942578633805601,"*",0.895432,"GOLGA8N","GO:0005794//Golgi apparatus","NA","NA","K20358//golgin subfamily A member 2","NP_001269423.1//golgin subfamily A member 8N [Homo sapiens]","1//3"]
[245711,1756,2.73,2.66,-0.0374747054186627,0.972969763939552,"*",0.935084,"SPDYA","GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0019901//protein kinase binding","GO:0007140//male meiotic nuclear division;GO:0007275//multicellular organism development;GO:0000082//G1/S transition of mitotic cell cycle;GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0006974//cellular response to DNA damage stimulus;GO:0008284//positive regulation of cell proliferation","K08694//speedy","NP_877433.2//speedy protein A isoform 1 [Homo sapiens];NP_001008779.1//speedy protein A isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[4522,3466,64.22,62.58,-0.037321006484848,0.531114400140895,"*",0.377572,"MTHFD1","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005739//mitochondrion","GO:0004488//methylenetetrahydrofolate dehydrogenase (NADP+) activity;GO:0016787//hydrolase activity;GO:0005524//ATP binding;GO:0004329//formate-tetrahydrofolate ligase activity;GO:0004487//methylenetetrahydrofolate dehydrogenase (NAD+) activity","GO:0019346//transsulfuration;GO:0061053//somite development;GO:0007507//heart development;GO:0001780//neutrophil homeostasis;GO:0006164//purine nucleotide biosynthetic process;GO:0035999//tetrahydrofolate interconversion;GO:0009257//10-formyltetrahydrofolate biosynthetic process;GO:0001843//neural tube closure;GO:0009070//serine family amino acid biosynthetic process;GO:0009086//methionine biosynthetic process","K00288//methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3]","XP_016781707.1//PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Pan troglodytes]","3//A2MP1"]
[64326,2695,9.01,8.78,-0.0373061662781805,0.700040860782257,"*",0.584872,"COP1","GO:0005654//nucleoplasm;GO:0031464//Cul4A-RING E3 ubiquitin ligase complex;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0000139//Golgi membrane","GO:0061630//ubiquitin protein ligase activity;GO:0046872//metal ion binding;GO:0004842//ubiquitin-protein transferase activity","GO:0043687//post-translational protein modification;GO:0010212//response to ionizing radiation;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process","K10143//E3 ubiquitin-protein ligase RFWD2 [EC:2.3.2.27]","NP_001001740.1//E3 ubiquitin-protein ligase RFWD2 isoform b [Homo sapiens];NP_071902.2//E3 ubiquitin-protein ligase RFWD2 isoform a [Homo sapiens];NP_001273573.1//E3 ubiquitin-protein ligase RFWD2 isoform c precursor [Homo sapiens]","6;1//3;3//A2MP1"]
[7485,1485,13.33,12.99,-0.0372753496410921,0.790271127534798,"*",0.700182,"WRB","NA","NA","NA","NA","XP_017381756.1//PREDICTED: tail-anchored protein insertion receptor WRB isoform X5 [Cebus capucinus imitator];NP_001337222.1//tail-anchored protein insertion receptor WRB isoform 3 [Homo sapiens];XP_017381755.1//PREDICTED: tail-anchored protein insertion receptor WRB isoform X4 [Cebus capucinus imitator];AAI11394.1//WRB protein, partial [Homo sapiens];XP_008984946.1//PREDICTED: tail-anchored protein insertion receptor WRB isoform X2 [Callithrix jacchus];XP_016793878.1//PREDICTED: tail-anchored protein insertion receptor WRB isoform X1 [Pan troglodytes]","1//3;2//1;5"]
[6903,1675,8.24,8.03,-0.0372443496659041,0.867887373929591,"*",0.79943,"TBCC","GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0032391//photoreceptor connecting cilium;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0015631//tubulin binding;GO:0051087//chaperone binding;GO:0003924//GTPase activity","GO:0006457//protein folding;GO:0007021//tubulin complex assembly;GO:0007023//post-chaperonin tubulin folding pathway","K21766//tubulin-specific chaperone C","EAX04100.1//tubulin-specific chaperone c [Homo sapiens]","2//1"]
[318,925,11.94,11.64,-0.036711778356521,0.921513201249917,"*",0.86769,"NUDT2","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0004081//bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity;GO:0008803//bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity;GO:0005525//GTP binding;GO:0008796//bis(5'-nucleosyl)-tetraphosphatase activity","GO:0034599//cellular response to oxidative stress;GO:0006139//nucleobase-containing compound metabolic process;GO:0006915//apoptotic process","K01518//bis(5'-nucleosidyl)-tetraphosphatase [EC:3.6.1.17]","XP_007967165.1//PREDICTED: bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] isoform X2 [Chlorocebus sabaeus];NP_001152.1//NUDT2 gene product [Homo sapiens];XP_005581528.2//PREDICTED: bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] isoform X1 [Macaca fascicularis]","4;1//3;2//1"]
[22926,7563,6.77,6.6,-0.0366898093291809,0.777788498676018,"*",0.680358,"ATF6","GO:0016020//membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005783//endoplasmic reticulum;GO:0005635//nuclear envelope;GO:0000139//Golgi membrane;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005789//endoplasmic reticulum membrane","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0042802//identical protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0046982//protein heterodimerization activity;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0003713//transcription coactivator activity;GO:0035497//cAMP response element binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0006457//protein folding;GO:0007165//signal transduction;GO:0006990//positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response;GO:0001654//eye development;GO:0006950//response to stress;GO:0007601//visual perception;GO:1990440//positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0043065//positive regulation of apoptotic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0036500//ATF6-mediated unfolded protein response","K09054//cyclic AMP-dependent transcription factor ATF-6 alpha","NP_031374.2//cyclic AMP-dependent transcription factor ATF-6 alpha [Homo sapiens]","3//A2MP1"]
[3678,4267,16.36,15.95,-0.036616324289517,0.734475678778536,"*",0.626378,"ITGA5","NA","NA","NA","K06484//integrin alpha 5","EAW96781.1//integrin, alpha 5 (fibronectin receptor, alpha polypeptide), isoform CRA_b [Homo sapiens]",4]
[140803,8250,0.8,0.78,-0.036525876025114,0.98306563287031,"*",0.94811,"TRPM6","GO:0016324//apical plasma membrane;GO:0031526//brush border membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0046872//metal ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0005262//calcium channel activity;GO:0005261//cation channel activity","GO:0070588//calcium ion transmembrane transport;GO:0051262//protein tetramerization;GO:0030001//metal ion transport;GO:0009636//response to toxic substance","K04981//transient receptor potential cation channel subfamily M member 6 [EC:2.7.11.1]","NP_001170781.1//transient receptor potential cation channel subfamily M member 6 isoform b [Homo sapiens];NP_060132.3//transient receptor potential cation channel subfamily M member 6 isoform a [Homo sapiens];NP_001170782.1//transient receptor potential cation channel subfamily M member 6 isoform c [Homo sapiens]","4;1//3"]
[51696,5621,1.2,1.17,-0.036525876025114,0.937508843051699,"*",0.88774,"HECA","GO:0016020//membrane;GO:0005634//nucleus;GO:0005737//cytoplasm","NA","GO:0045930//negative regulation of mitotic cell cycle;GO:0030323//respiratory tube development","K03129//transcription initiation factor TFIID subunit 4;K11305//histone acetyltransferase MYST3 [EC:2.3.1.48]","NP_057301.1//headcase protein homolog [Homo sapiens]","2//1"]
[6642,8332,11.22,10.94,-0.0364599378162364,0.684626577024881,"*",0.566722,"SNX1","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0010008//endosome membrane;GO:0030904//retromer complex;GO:0019898//extrinsic component of membrane;GO:0005764//lysosome;GO:0031982//vesicle;GO:0030027//lamellipodium;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0030905//retromer, tubulation complex;GO:0031901//early endosome membrane;GO:0043234//protein complex;GO:0005829//cytosol;GO:0005794//Golgi apparatus","GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity;GO:0005154//epidermal growth factor receptor binding;GO:0042803//protein homodimerization activity;GO:0035091//phosphatidylinositol binding;GO:0045296//cadherin binding;GO:1990460//leptin receptor binding;GO:1990459//transferrin receptor binding;GO:0005158//insulin receptor binding","GO:0031623//receptor internalization;GO:0042147//retrograde transport, endosome to Golgi;GO:0034498//early endosome to Golgi transport;GO:0006886//intracellular protein transport;GO:0016050//vesicle organization;GO:0045732//positive regulation of protein catabolic process;GO:0006897//endocytosis;GO:0072673//lamellipodium morphogenesis","K17917//sorting nexin-1/2","NP_001229862.1//sorting nexin-1 isoform d [Homo sapiens];XP_021569415.1//sorting nexin-1 isoform X3 [Carlito syrichta];NP_003090.2//sorting nexin-1 isoform a [Homo sapiens]","1//3;4;3//A2MP1"]
[5356,3374,10.84,10.57,-0.0363893799711885,0.818884347910728,"*",0.737324,"PLRG1","GO:0080008//Cul4-RING E3 ubiquitin ligase complex;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0000974//Prp19 complex;GO:0016607//nuclear speck;GO:0071013//catalytic step 2 spliceosome;GO:0001650//fibrillar center;GO:0071011//precatalytic spliceosome;GO:0005662//DNA replication factor A complex","NA","GO:1900087//positive regulation of G1/S transition of mitotic cell cycle;GO:0000398//mRNA splicing, via spliceosome;GO:0034504//protein localization to nucleus","K12862//pleiotropic regulator 1","NP_002660.1//pleiotropic regulator 1 isoform 1 [Homo sapiens];NP_001188493.1//pleiotropic regulator 1 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[79697,2502,16.89,16.47,-0.036328773075031,0.799638059146599,"*",0.710934,"RIOX1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus","GO:0032453//histone demethylase activity (H3-K4 specific);GO:0051864//histone demethylase activity (H3-K36 specific);GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;GO:0005506//iron ion binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0030961//peptidyl-arginine hydroxylation;GO:0006338//chromatin remodeling;GO:0045668//negative regulation of osteoblast differentiation;GO:0006351//transcription, DNA-templated;GO:0070544//histone H3-K36 demethylation;GO:0034720//histone H3-K4 demethylation","K16914//bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66 [EC:1.14.11.- 1.14.11.27]","XP_012359781.1//PREDICTED: LOW QUALITY PROTEIN: bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66 [Nomascus leucogenys]",4]
[4190,1482,87.75,85.57,-0.0362940348335387,0.64305488133631,"*",0.48682,"MDH1","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0043209//myelin sheath;GO:0005739//mitochondrion","GO:0047860//diiodophenylpyruvate reductase activity;GO:0004470//malic enzyme activity;GO:0051287//NAD binding;GO:0030060//L-malate dehydrogenase activity","GO:0006099//tricarboxylic acid cycle;GO:0006107//oxaloacetate metabolic process;GO:0006094//gluconeogenesis;GO:0005975//carbohydrate metabolic process;GO:0006734//NADH metabolic process;GO:0006108//malate metabolic process","K00025//malate dehydrogenase [EC:1.1.1.37]","NP_001186040.1//malate dehydrogenase, cytoplasmic isoform 2 [Homo sapiens];NP_001303303.1//malate dehydrogenase, peroxisomal isoform MDH1x [Homo sapiens]","1//3;3//A2MP1"]
[122961,1088,24.65,24.04,-0.0361507505540884,0.846095890489914,"*",0.771942,"ISCA2","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0051537//2 iron, 2 sulfur cluster binding;GO:0005506//iron ion binding;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0005198//structural molecule activity","GO:0097428//protein maturation by iron-sulfur cluster transfer;GO:0016226//iron-sulfur cluster assembly;GO:0051604//protein maturation;GO:0044281//small molecule metabolic process","K22072//iron-sulfur cluster assembly 2","CAD62580.1//unnamed protein product, partial [Homo sapiens]","1//3;3//A2MP1"]
[115353,1789,13.74,13.4,-0.0361490034729654,0.91301387095054,"*",0.857458,"LRRC42","NA","NA","NA","NA","XP_017359914.1//PREDICTED: leucine-rich repeat-containing protein 42 isoform X1 [Cebus capucinus imitator];NP_443172.1//leucine-rich repeat-containing protein 42 [Homo sapiens]","1//3;4"]
[80213,1374,14.55,14.19,-0.036144563735095,0.734197789312977,"*",0.632208,"TM2D3","GO:0016021//integral component of membrane","NA","NA","K01868//threonyl-tRNA synthetase [EC:6.1.1.3];K09488//TNF receptor-associated protein 1;K03511//DNA polymerase kappa [EC:2.7.7.7]","NP_001294889.1//TM2 domain-containing protein 3 isoform c precursor [Homo sapiens];NP_510883.2//TM2 domain-containing protein 3 isoform a precursor [Homo sapiens];EAX02314.1//TM2 domain containing 3, isoform CRA_b [Homo sapiens];NP_001294955.1//TM2 domain-containing protein 3 isoform d precursor [Homo sapiens]","1//3;3//A2MP1;2//1"]
[56983,3552,3.64,3.55,-0.0361194258066521,0.897443687663514,"*",0.837498,"POGLUT1","GO:0070062//extracellular exosome;GO:0005788//endoplasmic reticulum lumen","GO:0035252//UDP-xylosyltransferase activity;GO:0046527//glucosyltransferase activity;GO:0030158//protein xylosyltransferase activity;GO:0035251//UDP-glucosyltransferase activity","GO:0007369//gastrulation;GO:0045747//positive regulation of Notch signaling pathway;GO:0018242//protein O-linked glycosylation via serine;GO:0010470//regulation of gastrulation;GO:0060537//muscle tissue development;GO:0006664//glycolipid metabolic process;GO:0072358//cardiovascular system development;GO:0006493//protein O-linked glycosylation;GO:0001756//somitogenesis;GO:0048318//axial mesoderm development;GO:0048339//paraxial mesoderm development","K13667//protein glucosyltransferase [EC:2.4.1.-]","NP_689518.1//protein O-glucosyltransferase 1 precursor [Homo sapiens]","2//1"]
[51540,2544,17.89,17.45,-0.0359263509548938,0.790593386832439,"*",0.700616,"SCLY","GO:1902494//catalytic complex;GO:0005829//cytosol","GO:0070279//vitamin B6 binding;GO:0016829//lyase activity;GO:0009000//selenocysteine lyase activity;GO:0016597//amino acid binding;GO:0016740//transferase activity;GO:0042803//protein homodimerization activity","GO:0016261//selenocysteine catabolic process;GO:0006520//cellular amino acid metabolic process;GO:0001887//selenium compound metabolic process","K01763//selenocysteine lyase [EC:4.4.1.16]","NP_057594.4//selenocysteine lyase [Homo sapiens]",5]
[119504,3535,24,23.41,-0.0359094713838681,0.787991135295783,"*",0.697126,"ANAPC16","GO:0005829//cytosol;GO:0000776//kinetochore;GO:0000777//condensed chromosome kinetochore;GO:0005680//anaphase-promoting complex","NA","GO:0051301//cell division;GO:0016567//protein ubiquitination;GO:0007049//cell cycle","K01064//wingless-type MMTV integration site family, member 9","EHH20263.1//hypothetical protein EGK_03078, partial [Macaca mulatta];XP_006027950.1//PREDICTED: anaphase-promoting complex subunit 16 isoform X1 [Alligator sinensis];XP_011586098.1//PREDICTED: anaphase-promoting complex subunit 16 [Aquila chrysaetos canadensis]","1//3;3//A2MP1"]
[10969,1402,69.63,67.93,-0.0356601692172749,0.729933537182852,"*",0.626754,"EBNA1BP2","GO:0005634//nucleus;GO:0005730//nucleolus;GO:0034399//nuclear periphery;GO:0030687//preribosome, large subunit precursor","GO:0003723//RNA binding","GO:0006364//rRNA processing;GO:0042273//ribosomal large subunit biogenesis","K14823//rRNA-processing protein EBP2","XP_010370159.1//PREDICTED: probable rRNA-processing protein EBP2 [Rhinopithecus roxellana];XP_003812904.1//PREDICTED: probable rRNA-processing protein EBP2 [Pan paniscus]","1//3;2//1"]
[26097,2133,31.72,30.95,-0.0354533616023514,0.738406094090315,"*",0.63671,"CHTOP","GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0016607//nuclear speck;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0000346//transcription export complex","GO:0003723//RNA binding;GO:0008327//methyl-CpG binding","GO:0006406//mRNA export from nucleus;GO:0031062//positive regulation of histone methylation;GO:0006355//regulation of transcription, DNA-templated;GO:0006369//termination of RNA polymerase II transcription;GO:0031124//mRNA 3'-end processing;GO:0051096//positive regulation of helicase activity;GO:0006405//RNA export from nucleus;GO:0032781//positive regulation of ATPase activity;GO:0008284//positive regulation of cell proliferation","K08580//calpain-11 [EC:3.4.22.-];K12881//THO complex subunit 4;K13098//RNA-binding protein FUS;K12323//atrial natriuretic peptide receptor A [EC:4.6.1.2];K14859//ribosome biogenesis protein SSF1/2","OWK04629.1//hypothetical protein Celaphus_00001983, partial [Cervus elaphus hippelaphus]","1//3;3//A2MP1"]
[10325,2143,4.12,4.02,-0.0354488360042899,0.583479411001025,"*",0.427656,"RRAGB","GO:0005765//lysosomal membrane;GO:0005634//nucleus;GO:1990131//Gtr1-Gtr2 GTPase complex;GO:0034448//EGO complex;GO:0005829//cytosol;GO:0005764//lysosome;GO:0005737//cytoplasm","GO:0032561//guanyl ribonucleotide binding;GO:0046982//protein heterodimerization activity;GO:0051020//GTPase binding;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0016241//regulation of macroautophagy;GO:1904263//positive regulation of TORC1 signaling;GO:0034198//cellular response to amino acid starvation;GO:0032006//regulation of TOR signaling;GO:1990253//cellular response to leucine starvation;GO:0009267//cellular response to starvation;GO:0032008//positive regulation of TOR signaling;GO:0007050//cell cycle arrest;GO:0071230//cellular response to amino acid stimulus;GO:0034613//cellular protein localization;GO:0010506//regulation of autophagy","K16185//Ras-related GTP-binding protein A/B","NP_057740.2//ras-related GTP-binding protein B long isoform [Homo sapiens];XP_012891202.1//PREDICTED: ras-related GTP-binding protein B isoform X2 [Dipodomys ordii];NP_006055.3//ras-related GTP-binding protein B short isoform [Homo sapiens];XP_019524808.1//PREDICTED: ras-related GTP-binding protein B isoform X2 [Hipposideros armiger]","1//3;4;3//A2MP1"]
[29785,2660,52.34,51.07,-0.0354378653356189,0.631584338394794,"*",0.51036,"CYP2S1","GO:0005783//endoplasmic reticulum;GO:0031090//organelle membrane;GO:0005789//endoplasmic reticulum membrane","GO:0008395//steroid hydroxylase activity;GO:0020037//heme binding;GO:0008401//retinoic acid 4-hydroxylase activity;GO:0005506//iron ion binding;GO:0070330//aromatase activity;GO:0008392//arachidonic acid epoxygenase activity","GO:0019373//epoxygenase P450 pathway","K07420//cytochrome P450 family 2 subfamily S polypeptide 1 [EC:1.14.14.1]","BAB55227.1//unnamed protein product [Homo sapiens]",7]
[23478,1429,152.2,148.51,-0.0354082799051493,0.582829290952707,"*",0.425866,"SEC11A","GO:0070062//extracellular exosome;GO:0031090//organelle membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005787//signal peptidase complex","GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity","GO:0006465//signal peptide processing","K13280//signal peptidase I [EC:3.4.21.89]","XP_014444976.1//PREDICTED: signal peptidase complex catalytic subunit SEC11A [Tupaia chinensis];NP_001258848.1//signal peptidase complex catalytic subunit SEC11A isoform 6 [Homo sapiens];NP_001258850.1//signal peptidase complex catalytic subunit SEC11A isoform 1 [Homo sapiens];NP_001258851.1//signal peptidase complex catalytic subunit SEC11A isoform 3 [Homo sapiens];AAP97204.1//signal peptidase complex SPC-18 [Homo sapiens]","1//3;3//A2MP1"]
[55813,2065,19.42,18.95,-0.0353453523607383,0.810848420905338,"*",0.72552,"UTP6","GO:0034388//Pwp2p-containing subcomplex of 90S preribosome;GO:0005654//nucleoplasm;GO:0032040//small-subunit processome;GO:0005730//nucleolus","GO:0030515//snoRNA binding","GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006364//rRNA processing","K14557//U3 small nucleolar RNA-associated protein 6","NP_060898.2//U3 small nucleolar RNA-associated protein 6 homolog [Homo sapiens]","2//1"]
[83742,3250,51.41,50.17,-0.03522407398603,0.632317241218578,"*",0.475564,"MARVELD1","GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0045121//membrane raft;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0019911//structural constituent of myelin sheath","GO:0042552//myelination;GO:0001766//membrane raft polarization;GO:0008104//protein localization;GO:0007049//cell cycle","K22022//mucin-21;K14316//nuclear pore complex protein Nup121","NP_113672.1//MARVEL domain-containing protein 1 [Homo sapiens]","3//A2MP1"]
[50485,3150,10.03,9.79,-0.0349408410084857,0.885632336861978,"*",0.822262,"SMARCAL1","GO:0035861//site of double-strand break;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005662//DNA replication factor A complex","GO:0036310//annealing helicase activity;GO:0005524//ATP binding;GO:0004386//helicase activity;GO:0008094//DNA-dependent ATPase activity","GO:0090656//t-circle formation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006281//DNA repair;GO:0031297//replication fork processing;GO:0006259//DNA metabolic process;GO:0006974//cellular response to DNA damage stimulus","K14440//SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 [EC:3.6.4.12]","NP_054859.2//SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 [Homo sapiens]","1//3;3//A2MP1"]
[51626,1432,8.36,8.16,-0.034933790109387,0.925060067729084,"*",0.87213,"DYNC2LI1","GO:0005929//cilium;GO:0005874//microtubule;GO:0035869//ciliary transition zone;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0036064//ciliary basal body;GO:0097542//ciliary tip;GO:0031514//motile cilium;GO:0030990//intraciliary transport particle;GO:0005868//cytoplasmic dynein complex;GO:0045177//apical part of cell;GO:0005930//axoneme","GO:0003774//motor activity;GO:0008569//ATP-dependent microtubule motor activity, minus-end-directed;GO:0045504//dynein heavy chain binding","GO:0007368//determination of left/right symmetry;GO:1902017//regulation of cilium assembly;GO:0035735//intraciliary transport involved in cilium assembly;GO:0035721//intraciliary retrograde transport","K10417//dynein light intermediate chain 2, cytosolic","NP_056337.1//cytoplasmic dynein 2 light intermediate chain 1 isoform 2 [Homo sapiens];NP_001335842.1//cytoplasmic dynein 2 light intermediate chain 1 isoform 6 [Homo sapiens];NP_057092.2//cytoplasmic dynein 2 light intermediate chain 1 isoform 1 [Homo sapiens];NP_001335841.1//cytoplasmic dynein 2 light intermediate chain 1 isoform 5 [Homo sapiens];NP_001180393.1//cytoplasmic dynein 2 light intermediate chain 1 isoform 4 [Homo sapiens]","1//3;3//A2MP1"]
[2997,3502,26.38,25.75,-0.0348721322936016,0.750112512946622,"*",0.649246,"GYS1","GO:0016020//membrane;GO:0005829//cytosol;GO:0016234//inclusion body","GO:0004373//glycogen (starch) synthase activity;GO:0061547//glycogen synthase activity, transferring glucose-1-phosphate;GO:0005536//glucose binding;GO:0019901//protein kinase binding","GO:0005978//glycogen biosynthetic process;GO:0007507//heart development","K00693//glycogen synthase [EC:2.4.1.11]","NP_001155059.1//glycogen [starch] synthase, muscle isoform 2 [Homo sapiens];NP_002094.2//glycogen [starch] synthase, muscle isoform 1 [Homo sapiens]","1//3;4"]
[8999,4963,0.42,0.41,-0.0347654181606766,1.02146076861736,"*",0.994348,"CDKL2","GO:0005634//nucleus;GO:0005813//centrosome;GO:0005737//cytoplasm","GO:0004674//protein serine/threonine kinase activity;GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity","GO:0007548//sex differentiation;GO:0007165//signal transduction;GO:1903955//positive regulation of protein targeting to mitochondrion","K08824//cyclin-dependent kinase-like [EC:2.7.11.22]","NP_003939.1//cyclin-dependent kinase-like 2 isoform 1 [Homo sapiens];NP_001317653.1//cyclin-dependent kinase-like 2 isoform 2 [Homo sapiens]","1//3;4"]
[284427,1669,0.42,0.41,-0.0347654181606766,1.01909703225806,"*",0.996768,"SLC25A41","GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion","GO:0005347//ATP transmembrane transporter activity;GO:0015217//ADP transmembrane transporter activity","GO:0055085//transmembrane transport;GO:0006839//mitochondrial transport","K14684//solute carrier family 25 (mitochondrial phosphate transporter), member 23/24/25/41","NP_775908.2//solute carrier family 25 member 41 isoform a [Homo sapiens];EAW69094.1//hypothetical protein MGC34725, isoform CRA_b [Homo sapiens]","1//3;3//A2MP1"]
[4796,4519,19.36,18.9,-0.0346927181661596,0.709210759784882,"*",0.594398,"TONSL","GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0043596//nuclear replication fork;GO:0005737//cytoplasm","GO:0042393//histone binding;GO:0003714//transcription corepressor activity","GO:0042994//cytoplasmic sequestering of transcription factor;GO:0031297//replication fork processing;GO:0000724//double-strand break repair via homologous recombination","K09257//NF-kappa-B inhibitor-like protein 2","NP_038460.4//tonsoku-like protein [Homo sapiens]",4]
[28969,1872,35.19,34.36,-0.0344354776112011,0.732654728571429,"*",0.629274,"BZW2","GO:0016020//membrane;GO:0005737//cytoplasm","GO:0045296//cadherin binding","NA","K03260//translation initiation factor 4G;K03240//translation initiation factor eIF-2B subunit epsilon","XP_004431470.1//PREDICTED: basic leucine zipper and W2 domain-containing protein 2 isoform X1 [Ceratotherium simum simum];XP_518982.5//PREDICTED: basic leucine zipper and W2 domain-containing protein 2 isoform X1 [Pan troglodytes]","1//3;2//1"]
[57570,5419,4.68,4.57,-0.0343143645253347,0.636117349269588,"*",0.479776,"TRMT5","GO:0005759//mitochondrial matrix;GO:0005634//nucleus","GO:0052906//tRNA (guanine(37)-N(1))-methyltransferase activity","GO:0070901//mitochondrial tRNA methylation","K15429//tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]","NP_001337183.1//tRNA (guanine(37)-N1)-methyltransferase isoform 2 [Homo sapiens];XP_007985084.1//PREDICTED: tRNA (guanine(37)-N1)-methyltransferase [Chlorocebus sabaeus];NP_001337182.1//tRNA (guanine(37)-N1)-methyltransferase isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[22907,4114,24.71,24.13,-0.0342670951130332,0.689068271012524,"*",0.571736,"DHX30","GO:0042645//mitochondrial nucleoid;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0035770//ribonucleoprotein granule","GO:0003723//RNA binding;GO:0004004//ATP-dependent RNA helicase activity;GO:0005524//ATP binding;GO:0003682//chromatin binding;GO:0004386//helicase activity;GO:0003725//double-stranded RNA binding;GO:0003676//nucleic acid binding","GO:0006396//RNA processing;GO:1902775//mitochondrial large ribosomal subunit assembly","K13185//ATP-dependent RNA helicase DHX30 [EC:3.6.4.13]","NP_619520.1//putative ATP-dependent RNA helicase DHX30 isoform 1 [Homo sapiens];XP_016861403.1//PREDICTED: putative ATP-dependent RNA helicase DHX30 isoform X2 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[27077,1800,26.46,25.84,-0.0342069915847519,0.815368038156246,"*",0.733086,"B9D1","GO:0016020//membrane;GO:0036064//ciliary basal body;GO:0005829//cytosol;GO:0035869//ciliary transition zone;GO:0005813//centrosome;GO:0036038//MKS complex","GO:0008158//hedgehog receptor activity","GO:0043010//camera-type eye development;GO:0001701//in utero embryonic development;GO:0042733//embryonic digit morphogenesis;GO:0001944//vasculature development;GO:0060271//cilium assembly;GO:0097711//ciliary basal body-plasma membrane docking;GO:0032880//regulation of protein localization;GO:0007224//smoothened signaling pathway;GO:0060563//neuroepithelial cell differentiation","K16744//B9 domain-containing protein 1","NP_001230402.1//B9 domain-containing protein 1 isoform a [Homo sapiens];EAW50880.1//B9 protein, isoform CRA_c [Homo sapiens];EAW50878.1//B9 protein, isoform CRA_a [Homo sapiens];EAW50879.1//B9 protein, isoform CRA_b [Homo sapiens]","4;1//3;2//1"]
[3684,4742,0.43,0.42,-0.0339473319233377,0.942640751812311,"*",0.895432,"ITGAM","GO:0070062//extracellular exosome;GO:0034688//integrin alphaM-beta2 complex;GO:0005615//extracellular space;GO:0009897//external side of plasma membrane;GO:0044853//plasma membrane raft;GO:0008305//integrin complex;GO:0009986//cell surface;GO:0035579//specific granule membrane;GO:0070821//tertiary granule membrane;GO:0005886//plasma membrane","GO:0046872//metal ion binding;GO:0031072//heat shock protein binding;GO:0001851//complement component C3b binding;GO:0046982//protein heterodimerization activity","GO:0032930//positive regulation of superoxide anion generation;GO:0006911//phagocytosis, engulfment;GO:0097242//amyloid-beta clearance;GO:2000363//positive regulation of prostaglandin-E synthase activity;GO:0043312//neutrophil degranulation;GO:0007229//integrin-mediated signaling pathway;GO:0001774//microglial cell activation;GO:0034142//toll-like receptor 4 signaling pathway;GO:0050900//leukocyte migration;GO:1903980//positive regulation of microglial cell activation;GO:1901216//positive regulation of neuron death;GO:0010668//ectodermal cell differentiation;GO:0043315//positive regulation of neutrophil degranulation;GO:0007155//cell adhesion;GO:0045963//negative regulation of dopamine metabolic process;GO:0030198//extracellular matrix organization;GO:0098742//cell-cell adhesion via plasma-membrane adhesion molecules;GO:0090314//positive regulation of protein targeting to membrane","K06461//integrin alpha M","NP_001139280.1//integrin alpha-M isoform 1 precursor [Homo sapiens];XP_008957894.1//PREDICTED: integrin alpha-M isoform X2 [Pan paniscus]","1//3;3//A2MP1"]
[5707,3329,74.07,72.36,-0.0336969292426969,0.561906825220856,"*",0.406146,"PSMD1","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000502//proteasome complex;GO:0022624//proteasome accessory complex;GO:0005838//proteasome regulatory particle;GO:0034515//proteasome storage granule;GO:0035578//azurophil granule lumen;GO:0005829//cytosol;GO:0005576//extracellular region;GO:0008540//proteasome regulatory particle, base subcomplex","GO:0030234//enzyme regulator activity","GO:0043687//post-translational protein modification;GO:0038061//NIK/NF-kappaB signaling;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0006521//regulation of cellular amino acid metabolic process;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0016579//protein deubiquitination;GO:0043312//neutrophil degranulation;GO:0043488//regulation of mRNA stability;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0000209//protein polyubiquitination;GO:0055085//transmembrane transport;GO:0000165//MAPK cascade;GO:0050852//T cell receptor signaling pathway;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0042176//regulation of protein catabolic process;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:1902036//regulation of hematopoietic stem cell differentiation","K03032//26S proteasome regulatory subunit N2","XP_008528275.1//PREDICTED: 26S proteasome non-ATPase regulatory subunit 1 isoform X2 [Equus przewalskii];NP_001177966.1//26S proteasome non-ATPase regulatory subunit 1 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[5164,2444,14.75,14.41,-0.0336446189618184,0.782014634803574,"*",0.69037,"PDK2","GO:0005759//mitochondrial matrix;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005967//mitochondrial pyruvate dehydrogenase complex","GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0004672//protein kinase activity;GO:0004740//pyruvate dehydrogenase (acetyl-transferring) kinase activity;GO:0042803//protein homodimerization activity","GO:0010565//regulation of cellular ketone metabolic process;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:0006006//glucose metabolic process;GO:0008286//insulin receptor signaling pathway;GO:0034614//cellular response to reactive oxygen species;GO:0006885//regulation of pH;GO:0006111//regulation of gluconeogenesis;GO:0010510//regulation of acetyl-CoA biosynthetic process from pyruvate;GO:0031670//cellular response to nutrient;GO:0042593//glucose homeostasis;GO:0010906//regulation of glucose metabolic process","K00898//pyruvate dehydrogenase kinase 2/3/4 [EC:2.7.11.2]","XP_523791.4//PREDICTED: pyruvate dehydrogenase kinase, isozyme 2 isoform X1 [Pan troglodytes];XP_003281289.2//PREDICTED: pyruvate dehydrogenase kinase, isozyme 2 isoform X1 [Nomascus leucogenys]","4;1//3"]
[60682,3253,9.12,8.91,-0.0336083926428195,0.775875750161163,"*",0.678102,"SMAP1","GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0030276//clathrin binding;GO:0005096//GTPase activator activity","GO:0045648//positive regulation of erythrocyte differentiation;GO:2000369//regulation of clathrin-dependent endocytosis","K12486//stromal membrane-associated protein","NP_001037770.1//stromal membrane-associated protein 1 isoform A [Homo sapiens];NP_068759.2//stromal membrane-associated protein 1 isoform B [Homo sapiens];NP_001268368.1//stromal membrane-associated protein 1 isoform C [Homo sapiens];NP_001268369.1//stromal membrane-associated protein 1 isoform D [Homo sapiens]","4;1//3;2//1"]
[284370,3835,0.87,0.85,-0.0335525597110265,0.831783006358861,"*",0.753364,"ZNF615","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","NP_940882.3//zinc finger protein 615 isoform 2 [Homo sapiens];NP_001308252.1//zinc finger protein 615 isoform 5 [Homo sapiens];NP_001308246.1//zinc finger protein 615 isoform 3 [Homo sapiens];NP_001186253.1//zinc finger protein 615 isoform 1 [Homo sapiens];NP_001308251.1//zinc finger protein 615 isoform 4 [Homo sapiens];NP_001308247.1//zinc finger protein 615 isoform 4 [Homo sapiens]","1//3;3//A2MP1"]
[89848,4333,4.81,4.7,-0.0333761372050423,0.87620360170697,"*",0.809778,"FCHSD1","GO:0031594//neuromuscular junction;GO:0055037//recycling endosome","NA","GO:0030833//regulation of actin filament polymerization;GO:0007274//neuromuscular synaptic transmission","K20125//F-BAR and double SH3 domains protein","NP_258260.1//F-BAR and double SH3 domains protein 1 [Homo sapiens]","2//1"]
[389333,3251,0.88,0.86,-0.0331668639351993,0.95541517625475,"*",0.91283,"PROB1","NA","NA","NA","K16628//collagen, type VII, alpha;K22020//mucin-19","NP_001155018.1//proline-rich basic protein 1 [Homo sapiens]","1//3"]
[80832,3251,1.76,1.72,-0.0331668639351993,0.978560407202756,"*",0.942356,"APOL4","GO:0043231//intracellular membrane-bounded organelle;GO:0005615//extracellular space","GO:0008289//lipid binding","GO:0006869//lipid transport;GO:0042157//lipoprotein metabolic process;GO:0006629//lipid metabolic process","K14480//apolipoprotein L","NP_663693.1//apolipoprotein L4 isoform 2 precursor [Homo sapiens];NP_085146.2//apolipoprotein L4 isoform 1 [Homo sapiens]","4;2//1"]
[79623,2732,26.45,25.85,-0.0331034417990909,0.780490987631372,"*",0.683406,"GALNT14","GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0004653//polypeptide N-acetylgalactosaminyltransferase activity;GO:0046872//metal ion binding;GO:0030246//carbohydrate binding;GO:0016757//transferase activity, transferring glycosyl groups","GO:0006486//protein glycosylation;GO:0016266//O-glycan processing","K00710//polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41]","NP_001240756.1//polypeptide N-acetylgalactosaminyltransferase 14 isoform 3 [Homo sapiens];XP_016860395.1//PREDICTED: polypeptide N-acetylgalactosaminyltransferase 14 isoform X1 [Homo sapiens];NP_001240755.1//polypeptide N-acetylgalactosaminyltransferase 14 isoform 2 [Homo sapiens];NP_078848.2//polypeptide N-acetylgalactosaminyltransferase 14 isoform 1 [Homo sapiens];NP_001316026.1//polypeptide N-acetylgalactosaminyltransferase 14 isoform 6 [Homo sapiens]","1//3;3//A2MP1"]
[55108,3361,11.06,10.81,-0.0329848625000567,0.550253289535593,"*",0.395346,"BSDC1","NA","NA","NA","K20858//calcium uniporter protein, mitochondrial","NP_001137361.1//BSD domain-containing protein 1 isoform c [Homo sapiens];NP_001137362.1//BSD domain-containing protein 1 isoform d [Homo sapiens];NP_001137360.1//BSD domain-containing protein 1 isoform a [Homo sapiens];NP_060515.3//BSD domain-containing protein 1 isoform b [Homo sapiens];NP_001287887.1//BSD domain-containing protein 1 isoform e [Homo sapiens]","1//3;7;2//1"]
[389084,2786,6.21,6.07,-0.0328967519647993,0.889563554208754,"*",0.82697,"SNORC","NA","NA","NA","K16628//collagen, type VII, alpha;K06236//collagen, type I, alpha;K22020//mucin-19","XP_008963975.1//PREDICTED: uncharacterized protein LOC100977774 [Pan paniscus];XP_016859569.1//PREDICTED: uncharacterized protein C2orf82 isoform X1 [Homo sapiens]","1//3;2//1"]
[11149,5589,2.22,2.17,-0.0328646339056268,0.7914603183391,"*",0.701632,"BVES","GO:0005901//caveola;GO:0042383//sarcolemma;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0005923//bicellular tight junction;GO:0016328//lateral plasma membrane;GO:0005886//plasma membrane","GO:0030552//cAMP binding;GO:0005198//structural molecule activity","GO:0002931//response to ischemia;GO:0090136//epithelial cell-cell adhesion;GO:0034446//substrate adhesion-dependent cell spreading;GO:0001921//positive regulation of receptor recycling;GO:0007507//heart development;GO:0007517//muscle organ development;GO:0008360//regulation of cell shape;GO:0040017//positive regulation of locomotion;GO:0016192//vesicle-mediated transport;GO:0043087//regulation of GTPase activity;GO:0007519//skeletal muscle tissue development","K21108//blood vessel epicardial substance","XP_011808261.1//PREDICTED: blood vessel epicardial substance isoform X1 [Colobus angolensis palliatus];NP_671488.1//blood vessel epicardial substance [Homo sapiens]","1//3;4;3//A2MP1"]
[93010,3641,0.89,0.87,-0.0327899351176695,0.960379282051282,"*",0.919136,"B3GNT7","GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0008499//UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity;GO:0008532//N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity","GO:0018146//keratan sulfate biosynthetic process;GO:0016266//O-glycan processing","K09664//beta-1,3-N-acetylglucosaminyltransferase 7 [EC:2.4.1.-]","NP_660279.1//UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7 [Homo sapiens]","2//1"]
[182,5988,12.53,12.25,-0.0326046654319276,0.758111989329488,"*",0.658258,"JAG1","GO:0016020//membrane;GO:0005887//integral component of plasma membrane;GO:0016324//apical plasma membrane;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005912//adherens junction","GO:0008083//growth factor activity;GO:0005509//calcium ion binding;GO:0005112//Notch binding;GO:0005198//structural molecule activity;GO:0005543//phospholipid binding","GO:0072070//loop of Henle development;GO:0045747//positive regulation of Notch signaling pathway;GO:0061309//cardiac neural crest cell development involved in outflow tract morphogenesis;GO:0042127//regulation of cell proliferation;GO:0045445//myoblast differentiation;GO:0045446//endothelial cell differentiation;GO:0061073//ciliary body morphogenesis;GO:0003215//cardiac right ventricle morphogenesis;GO:0060411//cardiac septum morphogenesis;GO:0001525//angiogenesis;GO:0045599//negative regulation of fat cell differentiation;GO:0001974//blood vessel remodeling;GO:0072006//nephron development;GO:0042491//inner ear auditory receptor cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007220//Notch receptor processing;GO:0072015//glomerular visceral epithelial cell development;GO:0007219//Notch signaling pathway;GO:0097150//neuronal stem cell population maintenance;GO:0007399//nervous system development;GO:0030216//keratinocyte differentiation;GO:0002456//T cell mediated immunity;GO:0061156//pulmonary artery morphogenesis;GO:0035909//aorta morphogenesis;GO:0003184//pulmonary valve morphogenesis;GO:0061444//endocardial cushion cell development;GO:0002011//morphogenesis of an epithelial sheet;GO:0072017//distal tubule development;GO:0030334//regulation of cell migration;GO:0030097//hemopoiesis;GO:0061314//Notch signaling involved in heart development;GO:0045602//negative regulation of endothelial cell differentiation;GO:0001709//cell fate determination;GO:0032495//response to muramyl dipeptide;GO:0045639//positive regulation of myeloid cell differentiation;GO:0045669//positive regulation of osteoblast differentiation;GO:2000737//negative regulation of stem cell differentiation;GO:0045665//negative regulation of neuron differentiation","K06052//jagged-1","NP_000205.1//protein jagged-1 precursor [Homo sapiens]","2//1"]
[11161,1576,48.78,47.69,-0.0326029754018265,0.758289960348929,"*",0.65846,"ERG28","GO:0016021//integral component of membrane","NA","NA","NA","AAF28966.1//HSPC288, partial [Homo sapiens]","3//A2MP1"]
[55063,2372,0.9,0.88,-0.0324214776923775,0.94415323139734,"*",0.897578,"ZCWPW1","NA","GO:0008270//zinc ion binding","NA","K11424//histone-lysine N-methyltransferase NSD2 [EC:2.1.1.43]","NP_001244937.1//zinc finger CW-type PWWP domain protein 1 isoform 2 [Homo sapiens];NP_060454.3//zinc finger CW-type PWWP domain protein 1 isoform 1 [Homo sapiens]","4;1//3"]
[80818,4353,1.8,1.76,-0.0324214776923775,0.944534658766212,"*",0.898118,"ZNF436","GO:0005654//nucleoplasm;GO:0005829//cytosol","GO:0046872//metal ion binding;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated","K09230//SCAN domain-containing zinc finger protein","XP_013966140.1//zinc finger protein 436 isoform X2 [Canis lupus familiaris]","1//3;2//1"]
[10421,3448,27.22,26.62,-0.0321564955921028,0.72243266701345,"*",0.6086,"CD2BP2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005682//U5 snRNP;GO:0016607//nuclear speck;GO:0001650//fibrillar center;GO:0005737//cytoplasm","GO:0043021//ribonucleoprotein complex binding","GO:0000244//spliceosomal tri-snRNP complex assembly;GO:0000398//mRNA splicing, via spliceosome;GO:0010923//negative regulation of phosphatase activity","K13099//CD2 antigen cytoplasmic tail-binding protein 2","NP_006101.1//CD2 antigen cytoplasmic tail-binding protein 2 [Homo sapiens]","1//3;2//1"]
[3949,5177,24.51,23.97,-0.0321405752177068,0.438018759139179,"*",0.291784,"LDLR","GO:0016020//membrane;GO:0010008//endosome membrane;GO:0016323//basolateral plasma membrane;GO:0005615//extracellular space;GO:0005770//late endosome;GO:0009897//external side of plasma membrane;GO:0034362//low-density lipoprotein particle;GO:0036020//endolysosome membrane;GO:0043235//receptor complex;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0097443//sorting endosome;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005769//early endosome;GO:0036477//somatodendritic compartment;GO:0005622//intracellular;GO:0005764//lysosome;GO:0009986//cell surface;GO:1990666//PCSK9-LDLR complex;GO:0005905//clathrin-coated pit;GO:0005794//Golgi apparatus;GO:0045177//apical part of cell","GO:0002020//protease binding;GO:0032050//clathrin heavy chain binding;GO:0005041//low-density lipoprotein receptor activity;GO:0001540//amyloid-beta binding;GO:0030229//very-low-density lipoprotein particle receptor activity;GO:0030169//low-density lipoprotein particle binding;GO:0042802//identical protein binding;GO:0005509//calcium ion binding;GO:0001618//virus receptor activity","GO:0010867//positive regulation of triglyceride biosynthetic process;GO:0045807//positive regulation of endocytosis;GO:0030301//cholesterol transport;GO:0034382//chylomicron remnant clearance;GO:0061889//negative regulation of astrocyte activation;GO:1903979//negative regulation of microglial cell activation;GO:0010628//positive regulation of gene expression;GO:0090181//regulation of cholesterol metabolic process;GO:0006898//receptor-mediated endocytosis;GO:0030299//intestinal cholesterol absorption;GO:0042159//lipoprotein catabolic process;GO:2000188//regulation of cholesterol homeostasis;GO:0006629//lipid metabolic process;GO:0071404//cellular response to low-density lipoprotein particle stimulus;GO:0008203//cholesterol metabolic process;GO:0097242//amyloid-beta clearance;GO:0010899//regulation of phosphatidylcholine catabolic process;GO:0010629//negative regulation of gene expression;GO:0050729//positive regulation of inflammatory response;GO:0071398//cellular response to fatty acid;GO:0007616//long-term memory;GO:0010986//positive regulation of lipoprotein particle clearance;GO:1900223//positive regulation of amyloid-beta clearance;GO:0015914//phospholipid transport;GO:0034381//plasma lipoprotein particle clearance;GO:0090118//receptor-mediated endocytosis involved in cholesterol transport;GO:0006897//endocytosis;GO:0070508//cholesterol import;GO:0042632//cholesterol homeostasis;GO:0061771//response to caloric restriction;GO:1905907//negative regulation of amyloid fibril formation;GO:0034383//low-density lipoprotein particle clearance;GO:0051246//regulation of protein metabolic process;GO:0061024//membrane organization;GO:0051248//negative regulation of protein metabolic process;GO:1905167//positive regulation of lysosomal protein catabolic process","K12473//low-density lipoprotein receptor","BAD92646.1//low density lipoprotein receptor precursor variant, partial [Homo sapiens];NP_001182732.1//low-density lipoprotein receptor isoform 6 precursor [Homo sapiens];NP_001182729.1//low-density lipoprotein receptor isoform 4 precursor [Homo sapiens];NP_001182728.1//low-density lipoprotein receptor isoform 3 precursor [Homo sapiens]","4;1//3"]
[201163,3740,23.22,22.71,-0.0320402661586785,0.409412132834245,"*",0.267038,"FLCN","GO:0005929//cilium;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005764//lysosome;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0005085//guanyl-nucleotide exchange factor activity;GO:0032403//protein complex binding","GO:0032007//negative regulation of TOR signaling;GO:0007043//cell-cell junction assembly;GO:0010823//negative regulation of mitochondrion organization;GO:0045785//positive regulation of cell adhesion;GO:0010629//negative regulation of gene expression;GO:1901723//negative regulation of cell proliferation involved in kidney development;GO:0032008//positive regulation of TOR signaling;GO:0001932//regulation of protein phosphorylation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0043065//positive regulation of apoptotic process;GO:2001170//negative regulation of ATP biosynthetic process;GO:0001934//positive regulation of protein phosphorylation;GO:0032465//regulation of cytokinesis;GO:0051898//negative regulation of protein kinase B signaling;GO:0030097//hemopoiesis;GO:0030308//negative regulation of cell growth;GO:0031929//TOR signaling;GO:0032006//regulation of TOR signaling;GO:0035065//regulation of histone acetylation;GO:0001701//in utero embryonic development;GO:0030336//negative regulation of cell migration;GO:2000973//regulation of pro-B cell differentiation;GO:0010508//positive regulation of autophagy;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:1900181//negative regulation of protein localization to nucleus;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:2000506//negative regulation of energy homeostasis;GO:0035024//negative regulation of Rho protein signal transduction","K09594//folliculin","NP_001340158.1//folliculin isoform 3 [Homo sapiens];NP_653207.1//folliculin isoform 2 [Homo sapiens];XP_018882612.1//PREDICTED: folliculin isoform X1 [Gorilla gorilla gorilla]","6;1//3"]
[7553,2286,10.49,10.26,-0.0319839469702135,0.528680152639087,"*",0.371208,"ZNF7","GO:0005634//nucleus;GO:0005622//intracellular","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0007275//multicellular organism development;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","XP_017739070.1//PREDICTED: zinc finger protein 7 isoform X12 [Rhinopithecus bieti];XP_017739063.1//PREDICTED: zinc finger protein 7 isoform X7 [Rhinopithecus bieti];NP_001317552.1//zinc finger protein 7 isoform 5 [Homo sapiens];XP_017739068.1//PREDICTED: zinc finger protein 7 isoform X10 [Rhinopithecus bieti];XP_017739062.1//PREDICTED: zinc finger protein 7 isoform X6 [Rhinopithecus bieti];XP_017739069.1//PREDICTED: zinc finger protein 7 isoform X11 [Rhinopithecus bieti];XP_017739058.1//PREDICTED: zinc finger protein 7 isoform X2 [Rhinopithecus bieti]","1//3;3//A2MP1"]
[143282,2564,1.37,1.34,-0.0319428925027542,0.962738002744201,"*",0.922418,"FGFBP3","GO:0031012//extracellular matrix;GO:0005576//extracellular region","GO:0008201//heparin binding;GO:0017134//fibroblast growth factor binding","GO:0045743//positive regulation of fibroblast growth factor receptor signaling pathway;GO:0043117//positive regulation of vascular permeability","K13172//serine/arginine repetitive matrix protein 2","XP_007961726.1//PREDICTED: fibroblast growth factor-binding protein 3 isoform X1 [Chlorocebus sabaeus]",4]
[91010,11141,1.37,1.34,-0.0319428925027542,0.941249545196809,"*",0.893698,"FMNL3","GO:0043231//intracellular membrane-bounded organelle;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0003779//actin binding;GO:0017048//Rho GTPase binding;GO:0032794//GTPase activating protein binding","GO:0016477//cell migration;GO:0001525//angiogenesis;GO:0030036//actin cytoskeleton organization;GO:0007010//cytoskeleton organization;GO:0008360//regulation of cell shape","K05745//diaphanous 3;K04512//dishevelled associated activator of morphogenesis","NP_783863.4//formin-like protein 3 isoform 1 [Homo sapiens];NP_944489.2//formin-like protein 3 isoform 2 [Homo sapiens]","4;2//1"]
[7296,3889,281.87,275.7,-0.0319306697500869,0.0883056296377009,"*",0.0405872,"TXNRD1","GO:0070062//extracellular exosome;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005623//cell;GO:0001650//fibrillar center;GO:0005739//mitochondrion","GO:0015035//protein disulfide oxidoreductase activity;GO:0009055//electron transfer activity;GO:0050660//flavin adenine dinucleotide binding;GO:0004791//thioredoxin-disulfide reductase activity","GO:0001707//mesoderm formation;GO:0008283//cell proliferation;GO:0045454//cell redox homeostasis","K22182//thioredoxin reductase (NADPH) [EC:1.8.1.9]","XP_004373834.1//PREDICTED: thioredoxin reductase 1, cytoplasmic [Trichechus manatus latirostris];NP_001243891.1//thioredoxin reductase 1, cytoplasmic [Oryctolagus cuniculus];XP_007950590.1//PREDICTED: LOW QUALITY PROTEIN: thioredoxin reductase 1, cytoplasmic [Orycteropus afer afer]","1//3;3//A2MP1;2//1"]
[10626,2520,112.49,110.04,-0.0317687114164872,0.0301823381731835,"*",0.01193576,"TRIM16","GO:0016605//PML body;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0032089//NACHT domain binding;GO:0008270//zinc ion binding;GO:0019966//interleukin-1 binding","GO:0048386//positive regulation of retinoic acid receptor signaling pathway;GO:0050718//positive regulation of interleukin-1 beta secretion;GO:0045618//positive regulation of keratinocyte differentiation;GO:0032526//response to retinoic acid;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046683//response to organophosphorus;GO:0043966//histone H3 acetylation;GO:0043967//histone H4 acetylation;GO:0060416//response to growth hormone","K10266//F-box and WD-40 domain protein 10;K12006//tripartite motif-containing protein 16","NP_001340150.1//tripartite motif-containing protein 16-like protein isoform 3 [Homo sapiens];NP_006461.3//tripartite motif-containing protein 16 isoform a [Homo sapiens];NP_001335050.1//tripartite motif-containing protein 16 isoform b [Homo sapiens]","1//3;4"]
[153222,6359,0.46,0.45,-0.0317088597273381,1.02203968981064,"*",0.993376,"CREBRF","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0005737//cytoplasm","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding","GO:0006810//transport;GO:0034976//response to endoplasmic reticulum stress;GO:0032388//positive regulation of intracellular transport;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:1900102//negative regulation of endoplasmic reticulum unfolded protein response;GO:0045732//positive regulation of protein catabolic process;GO:1902213//positive regulation of prolactin signaling pathway;GO:0051222//positive regulation of protein transport;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0042711//maternal behavior;GO:1900170//negative regulation of glucocorticoid mediated signaling pathway","K21554//CREB3 regulatory factor","XP_017403141.1//PREDICTED: CREB3 regulatory factor-like isoform X1 [Cebus capucinus imitator];XP_004043054.2//PREDICTED: CREB3 regulatory factor isoform X1 [Gorilla gorilla gorilla]","1//3;2//1"]
[125111,4042,10.14,9.92,-0.0316456266164655,0.83273401257514,"*",0.754486,"GJD3","GO:0005922//connexin complex;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane","GO:0005216//ion channel activity;GO:0005243//gap junction channel activity","GO:0016264//gap junction assembly;GO:0009749//response to glucose;GO:0007154//cell communication","K07627//gap junction delta-3 protein","NP_689343.3//gap junction delta-3 protein [Homo sapiens]","3//A2MP1"]
[3838,2126,359.43,351.65,-0.0315706118117834,0.309643352288342,"*",0.183394,"KPNA2","GO:0016020//membrane;GO:0043657//host cell;GO:0005654//nucleoplasm;GO:0005643//nuclear pore;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0008565//protein transporter activity;GO:0042826//histone deacetylase binding;GO:0008139//nuclear localization sequence binding","GO:0019054//modulation by virus of host process;GO:0006607//NLS-bearing protein import into nucleus;GO:0075733//intracellular transport of virus;GO:0000018//regulation of DNA recombination;GO:0006259//DNA metabolic process","K15043//importin subunit alpha-2","NP_002257.1//importin subunit alpha-1 [Homo sapiens]","1//3;3//A2MP1"]
[81617,3512,0.94,0.92,-0.0310268956206244,0.959531274440518,"*",0.917964,"CAB39L","GO:0070062//extracellular exosome;GO:0005829//cytosol","NA","GO:0007050//cell cycle arrest","K08272//calcium binding protein 39","XP_011919654.1//PREDICTED: calcium-binding protein 39-like isoform X1 [Cercocebus atys]","1//3;3//A2MP1;2//1"]
[27042,8505,5.66,5.54,-0.030916076782694,0.815988302380621,"*",0.733848,"DIEXF","GO:0005654//nucleoplasm;GO:0032040//small-subunit processome;GO:0005730//nucleolus","GO:0034511//U3 snoRNA binding;GO:0003723//RNA binding;GO:0019843//rRNA binding","GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0007275//multicellular organism development;GO:0006364//rRNA processing","K14774//U3 small nucleolar RNA-associated protein 25","NP_055203.4//digestive organ expansion factor homolog [Homo sapiens]",6]
[222183,3673,3.8,3.72,-0.0306967972229166,0.936474429572808,"*",0.886526,"SRRM3","NA","NA","NA","K13172//serine/arginine repetitive matrix protein 2","NP_001103669.1//serine/arginine repetitive matrix protein 3 isoform b [Homo sapiens];NP_001278760.1//serine/arginine repetitive matrix protein 3 isoform a [Homo sapiens]","1//3;2//1"]
[283234,4932,0.95,0.93,-0.0306967972229164,0.9730965352443,"*",0.935084,"CCDC88B","GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005737//cytoplasm","GO:0051959//dynein light intermediate chain binding;GO:0008017//microtubule binding","GO:0042832//defense response to protozoan;GO:0042102//positive regulation of T cell proliferation;GO:0050870//positive regulation of T cell activation;GO:0001819//positive regulation of cytokine production;GO:0030705//cytoskeleton-dependent intracellular transport;GO:0031122//cytoplasmic microtubule organization","K16628//collagen, type VII, alpha","NP_115627.6//coiled-coil domain-containing protein 88B precursor [Homo sapiens]",5]
[254042,3129,2.86,2.8,-0.0305883198334231,0.909789144231412,"*",0.85255,"METAP1D","GO:0005739//mitochondrion","GO:0046872//metal ion binding;GO:0004177//aminopeptidase activity;GO:0008235//metalloexopeptidase activity","GO:0031365//N-terminal protein amino acid modification;GO:0018206//peptidyl-methionine modification","K01265//methionyl aminopeptidase [EC:3.4.11.18]","NP_954697.1//methionine aminopeptidase 1D, mitochondrial isoform 1 precursor [Homo sapiens];XP_003309462.1//PREDICTED: methionine aminopeptidase 1D, mitochondrial isoform X1 [Pan troglodytes];AAY55948.1//mitochondrial methionine aminopeptidase 3 [Homo sapiens]","1//3;2//1"]
[51016,931,31.48,30.82,-0.030568678992701,0.788486040458339,"*",0.69786,"EMC9","GO:0072546//ER membrane protein complex;GO:0005737//cytoplasm","NA","NA","K06697//proteasome activator subunit 2 (PA28 beta);K09291//nucleoprotein TPR","NP_057133.2//ER membrane protein complex subunit 9 isoform a [Homo sapiens];XP_007984475.1//PREDICTED: ER membrane protein complex subunit 9 isoform X1 [Chlorocebus sabaeus];XP_009209541.1//ER membrane protein complex subunit 9 isoform X1 [Papio anubis]","1//3;3//A2MP1"]
[119032,2436,7.66,7.5,-0.0304537965417138,0.835936339604438,"*",0.759376,"BORCS7","NA","NA","NA","K20821//BLOC-1 related complex subunit 7","XP_003825579.2//PREDICTED: UPF0693 protein C10orf32 homolog [Pan paniscus]","1//3;3//A2MP1"]
[84553,11498,0.96,0.94,-0.0303736490435189,0.885990500269687,"*",0.82265,"FAXC","GO:0016021//integral component of membrane","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K09239//human immunodeficiency virus type I enhancer-binding protein;K05746//enabled;K11447//histone demethylase [EC:1.14.11.-];K01064//wingless-type MMTV integration site family, member 9;K10367//formin 1","XP_015328316.1//PREDICTED: failed axon connections homolog isoform X1 [Bos taurus];XP_004862550.1//failed axon connections homolog isoform X2 [Heterocephalus glaber];EAW48486.1//chromosome 6 open reading frame 168, isoform CRA_d [Homo sapiens];XP_006055901.1//PREDICTED: failed axon connections homolog, partial [Bubalus bubalis];XP_017363172.1//PREDICTED: failed axon connections homolog isoform X1 [Cebus capucinus imitator]","1//3;3//A2MP1"]
[3728,3494,53.3,52.19,-0.0303621310260194,0.692690508438819,"*",0.575522,"JUP","NA","NA","NA","K10056//junction plakoglobin","XP_016787309.1//PREDICTED: junction plakoglobin isoform X1 [Pan troglodytes];XP_016787311.1//PREDICTED: junction plakoglobin isoform X3 [Pan troglodytes];XP_016787310.1//PREDICTED: junction plakoglobin isoform X2 [Pan troglodytes];AAH00441.2//JUP protein, partial [Homo sapiens]","1//3;3//A2MP1"]
[54751,2893,29.89,29.27,-0.030240151269344,0.633720315544472,"*",0.477254,"FBLIM1","GO:0001725//stress fiber;GO:0005925//focal adhesion;GO:0005938//cell cortex;GO:0005829//cytosol;GO:0001650//fibrillar center;GO:0030054//cell junction","GO:0046872//metal ion binding;GO:0031005//filamin binding","GO:0098609//cell-cell adhesion;GO:0033623//regulation of integrin activation;GO:0034329//cell junction assembly;GO:0008360//regulation of cell shape","K10447//kelch-like protein 9/13;K06273//zyxin","NP_060026.2//filamin-binding LIM protein 1 isoform a [Homo sapiens];NP_001019386.1//filamin-binding LIM protein 1 isoform b [Homo sapiens];NP_001019387.1//filamin-binding LIM protein 1 isoform c [Homo sapiens]","1//3;3//A2MP1;2//1"]
[84572,1255,18.83,18.44,-0.03019434418489,0.884228042099582,"*",0.82046,"GNPTG","GO:0070062//extracellular exosome;GO:0005794//Golgi apparatus;GO:0000139//Golgi membrane","GO:0003976//UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity;GO:0042803//protein homodimerization activity","GO:0016256//N-glycan processing to lysosome;GO:0046835//carbohydrate phosphorylation","K10087//N-acetylglucosamine-1-phosphate transferase, gamma subunit","NP_115909.1//N-acetylglucosamine-1-phosphotransferase subunit gamma precursor [Homo sapiens]",4]
[51271,2814,38.63,37.83,-0.0301909011825554,0.799048777292576,"*",0.71021,"UBAP1","GO:0043657//host cell;GO:0010008//endosome membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0000813//ESCRT I complex;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0043130//ubiquitin binding","GO:0016197//endosomal transport;GO:0075733//intracellular transport of virus;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0015031//protein transport;GO:0019058//viral life cycle","K22069//LYR motif-containing protein 4;K09228//KRAB domain-containing zinc finger protein;K05632//atrophin-1 interacting protein 4 [EC:2.3.2.26];K02159//apoptosis regulator BAX;K10477//BTB/POZ domain-containing protein 1/2","NP_001164672.1//ubiquitin-associated protein 1 isoform 2 [Homo sapiens];NP_057609.2//ubiquitin-associated protein 1 isoform 1 [Homo sapiens];NP_001164673.1//ubiquitin-associated protein 1 isoform 3 [Homo sapiens]","4;1//3;2//1"]
[63827,2998,2.92,2.86,-0.0299532221016278,0.822909415440156,"*",0.74203,"BCAN","GO:0043202//lysosomal lumen;GO:0005576//extracellular region;GO:0031225//anchored component of membrane;GO:0005578//proteinaceous extracellular matrix;GO:0005796//Golgi lumen","GO:0005201//extracellular matrix structural constituent;GO:0030246//carbohydrate binding;GO:0005540//hyaluronic acid binding","GO:0021766//hippocampus development;GO:0030208//dermatan sulfate biosynthetic process;GO:0030206//chondroitin sulfate biosynthetic process;GO:0007417//central nervous system development;GO:0022617//extracellular matrix disassembly;GO:0007155//cell adhesion;GO:0030198//extracellular matrix organization;GO:0030207//chondroitin sulfate catabolic process;GO:0001501//skeletal system development;GO:0030203//glycosaminoglycan metabolic process","K06795//brevican","NP_940819.1//brevican core protein isoform 2 precursor [Homo sapiens];XP_016857536.1//PREDICTED: brevican core protein isoform X1 [Homo sapiens]","4;1//3"]
[501,4953,9.8,9.6,-0.0297473433940522,0.834155859954423,"*",0.756192,"ALDH7A1","GO:0005759//mitochondrial matrix;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005739//mitochondrion","GO:0016491//oxidoreductase activity;GO:0004043//L-aminoadipate-semialdehyde dehydrogenase activity;GO:0008802//betaine-aldehyde dehydrogenase activity;GO:0004029//aldehyde dehydrogenase (NAD) activity","GO:0006081//cellular aldehyde metabolic process;GO:0019285//glycine betaine biosynthetic process from choline;GO:0007605//sensory perception of sound;GO:0006554//lysine catabolic process;GO:0042426//choline catabolic process","K14085//aldehyde dehydrogenase family 7 member A1 [EC:1.2.1.31 1.2.1.8 1.2.1.3]","XP_001157473.3//PREDICTED: alpha-aminoadipic semialdehyde dehydrogenase [Pan troglodytes];XP_011945494.1//PREDICTED: alpha-aminoadipic semialdehyde dehydrogenase [Cercocebus atys]","4;1//3"]
[92745,1993,0.49,0.48,-0.0297473433940521,1.0206330629891,"*",0.996098,"SLC38A5","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0015187//glycine transmembrane transporter activity;GO:0015171//amino acid transmembrane transporter activity","GO:0006865//amino acid transport","K14992//solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 5","XP_005272752.3//PREDICTED: sodium-coupled neutral amino acid transporter 5 isoform X2 [Homo sapiens]","3//A2MP1"]
[55096,1679,0.49,0.48,-0.0297473433940521,1.02010826020637,"*",0.996416,"EBLN2","NA","NA","NA","NA","NP_060499.3//endogenous Bornavirus-like nucleoprotein 2 [Homo sapiens]",4]
[266747,2988,0.98,0.96,-0.0297473433940521,1.02197386642623,"*",0.993376,"RGL4","GO:0031410//cytoplasmic vesicle;GO:0005622//intracellular","GO:0005085//guanyl-nucleotide exchange factor activity","GO:0007264//small GTPase mediated signal transduction","K08732//ral guanine nucleotide dissociation stimulator","EAW59595.1//Ral-GDS related protein Rgr, isoform CRA_b [Homo sapiens];NP_705843.1//ral-GDS-related protein isoform 2 precursor [Homo sapiens];NP_001316353.1//ral-GDS-related protein isoform 1 precursor [Homo sapiens]","1//3"]
[57147,2990,2.46,2.41,-0.0296251691092782,1.01999200593663,"*",0.989534,"SCYL3","GO:0005794//Golgi apparatus;GO:0030027//lamellipodium;GO:0005737//cytoplasm","GO:0005524//ATP binding;GO:0004672//protein kinase activity","GO:0016477//cell migration;GO:0006468//protein phosphorylation","K17542//SCY1-like protein 3","XP_003893591.2//protein-associating with the carboxyl-terminal domain of ezrin isoform X1 [Papio anubis];XP_003893590.2//protein-associating with the carboxyl-terminal domain of ezrin isoform X2 [Papio anubis]","6;3//A2MP1"]
[57617,3922,13.79,13.51,-0.0295947821882958,0.813172189984656,"*",0.72989,"VPS18","GO:0005765//lysosomal membrane;GO:0005770//late endosome;GO:0030136//clathrin-coated vesicle;GO:0031902//late endosome membrane;GO:0005764//lysosome;GO:0005768//endosome;GO:0005884//actin filament;GO:0030897//HOPS complex;GO:0030123//AP-3 adaptor complex;GO:0005776//autophagosome;GO:0005769//early endosome;GO:0033263//CORVET complex","GO:0003779//actin binding;GO:0046872//metal ion binding;GO:0030674//protein binding, bridging;GO:0019905//syntaxin binding","GO:0006904//vesicle docking involved in exocytosis;GO:0016192//vesicle-mediated transport;GO:0006886//intracellular protein transport;GO:0006914//autophagy;GO:0008333//endosome to lysosome transport;GO:0007032//endosome organization;GO:0035542//regulation of SNARE complex assembly;GO:0007040//lysosome organization;GO:0046718//viral entry into host cell","K20181//vacuolar protein sorting-associated protein 18","NP_065908.1//vacuolar protein sorting-associated protein 18 homolog [Homo sapiens]","2//1"]
[10130,2349,146.8,143.84,-0.0293870422161279,0.555478221411192,"*",0.400178,"PDIA6","GO:0070062//extracellular exosome;GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0042470//melanosome;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0034663//endoplasmic reticulum chaperone complex;GO:0005829//cytosol;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane","GO:0003756//protein disulfide isomerase activity;GO:0015037//peptide disulfide oxidoreductase activity","GO:0006457//protein folding;GO:0043687//post-translational protein modification;GO:0034976//response to endoplasmic reticulum stress;GO:0030168//platelet activation;GO:0043277//apoptotic cell clearance;GO:0045454//cell redox homeostasis;GO:0044267//cellular protein metabolic process;GO:0036498//IRE1-mediated unfolded protein response;GO:0070527//platelet aggregation","K09584//protein disulfide-isomerase A6 [EC:5.3.4.1]","NP_001269634.1//protein disulfide-isomerase A6 isoform b [Homo sapiens];NP_005733.1//protein disulfide-isomerase A6 isoform d precursor [Homo sapiens];NP_001269633.1//protein disulfide-isomerase A6 isoform a [Homo sapiens];NP_001269636.1//protein disulfide-isomerase A6 isoform e precursor [Homo sapiens]","1//3;3//A2MP1"]
[79654,3628,10.92,10.7,-0.0293620596313432,0.847592577698532,"*",0.773732,"HECTD3","GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm","GO:0061630//ubiquitin protein ligase activity;GO:0019905//syntaxin binding;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity","GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process","K12233//E3 ubiquitin-protein ligase HECTD3 [EC:2.3.2.26]","XP_017737303.1//PREDICTED: E3 ubiquitin-protein ligase HECTD3 [Rhinopithecus bieti]",5]
[752,3973,17.94,17.58,-0.0292448197758575,0.789859668739401,"*",0.699768,"FMNL1","GO:0045335//phagocytic vesicle;GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005938//cell cortex;GO:0032059//bleb;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0051015//actin filament binding;GO:0005522//profilin binding;GO:0048365//Rac GTPase binding;GO:0032794//GTPase activating protein binding","GO:0006929//substrate-dependent cell migration;GO:0030866//cortical actin cytoskeleton organization;GO:0008360//regulation of cell shape;GO:0051014//actin filament severing","K04512//dishevelled associated activator of morphogenesis;K05741//diaphanous 2","NP_005883.2//formin-like protein 1 [Homo sapiens]","3//A2MP1"]
[374868,4467,5.49,5.38,-0.0291999764485746,0.889731479033452,"*",0.827516,"ATP9B","GO:0005768//endosome;GO:0016021//integral component of membrane;GO:0005802//trans-Golgi network;GO:0005886//plasma membrane;GO:0048471//perinuclear region of cytoplasm","GO:0000287//magnesium ion binding;GO:0005524//ATP binding;GO:0004012//phospholipid-translocating ATPase activity","GO:0045332//phospholipid translocation;GO:0006897//endocytosis;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER","K01530//phospholipid-translocating ATPase [EC:3.6.3.1]","XP_009250766.1//PREDICTED: probable phospholipid-transporting ATPase IIB isoform X1 [Pongo abelii]","4;1//3"]
[84627,13203,6.99,6.85,-0.0291884675275474,0.765333924585219,"*",0.667068,"ZNF469","NA","GO:0046872//metal ion binding;GO:0003676//nucleic acid binding","NA","K22020//mucin-19","NP_001120936.2//zinc finger protein 469 [Homo sapiens]","2//1"]
[146434,5516,0.5,0.49,-0.0291463456595165,0.954437598793759,"*",0.911418,"ZNF597","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","XP_004438190.1//PREDICTED: zinc finger protein 597 isoform X1 [Ceratotherium simum simum]","2//1"]
[5924,8171,0.5,0.49,-0.0291463456595165,0.968066708330615,"*",0.928978,"RASGRF2","GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane","GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005516//calmodulin binding;GO:0005089//Rho guanyl-nucleotide exchange factor activity","GO:0043065//positive regulation of apoptotic process;GO:0000165//MAPK cascade;GO:0007264//small GTPase mediated signal transduction;GO:0034976//response to endoplasmic reticulum stress;GO:0035023//regulation of Rho protein signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction","K12326//Ras-specific guanine nucleotide-releasing factor 2","NP_008840.1//ras-specific guanine nucleotide-releasing factor 2 [Homo sapiens]","2//1"]
[199953,3873,11.55,11.32,-0.0290188934715377,0.860483699543317,"*",0.790294,"TMEM201","GO:0000922//spindle pole;GO:0005635//nuclear envelope;GO:0005639//integral component of nuclear inner membrane;GO:0005737//cytoplasm","GO:0051015//actin filament binding;GO:0005521//lamin binding","GO:0051642//centrosome localization;GO:0090435//protein localization to nuclear envelope;GO:0007097//nuclear migration;GO:0006998//nuclear envelope organization;GO:0010761//fibroblast migration","K10955//mucin-2;K22020//mucin-19;K13908//mucin-5B","NP_001124396.2//transmembrane protein 201 isoform 1 [Homo sapiens];NP_001010866.1//transmembrane protein 201 isoform 2 [Homo sapiens]","3//A2MP1;2//1"]
[81794,3434,10.05,9.85,-0.0289998717225525,0.755216311268317,"*",0.65494,"ADAMTS10","GO:0031012//extracellular matrix;GO:0001527//microfibril;GO:0005578//proteinaceous extracellular matrix","GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding","GO:0007229//integrin-mediated signaling pathway","K08625//a disintegrin and metalloproteinase with thrombospondin motifs 10 [EC:3.4.24.-]","XP_014197944.1//PREDICTED: A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X1 [Pan paniscus];NP_001269281.1//A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[10868,4538,2.02,1.98,-0.0288548626721851,0.870849811787072,"*",0.802922,"USP20","GO:0005829//cytosol;GO:0005813//centrosome;GO:0048471//perinuclear region of cytoplasm","GO:0004843//thiol-dependent ubiquitin-specific protease activity;GO:0001664//G-protein coupled receptor binding;GO:0004197//cysteine-type endopeptidase activity;GO:0008270//zinc ion binding;GO:0036459//thiol-dependent ubiquitinyl hydrolase activity","GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0071108//protein K48-linked deubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination;GO:0006897//endocytosis;GO:0070536//protein K63-linked deubiquitination","K11848//ubiquitin carboxyl-terminal hydrolase 20/33 [EC:3.4.19.12]","NP_001103773.2//ubiquitin carboxyl-terminal hydrolase 20 [Homo sapiens]","4;3//A2MP1;7"]
[4324,4268,9.6,9.41,-0.0288396828799817,0.850796923371648,"*",0.778468,"MMP15","GO:0031012//extracellular matrix;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane","GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding;GO:0008047//enzyme activator activity;GO:0070006//metalloaminopeptidase activity","GO:0022617//extracellular matrix disassembly;GO:0032355//response to estradiol;GO:0006508//proteolysis;GO:0006464//cellular protein modification process;GO:0035987//endodermal cell differentiation;GO:0030574//collagen catabolic process","K07995//matrix metalloproteinase-15 (membrane-inserted) [EC:3.4.24.-]","NP_002419.1//matrix metalloproteinase-15 preproprotein [Homo sapiens]","3//A2MP1"]
[112942,1324,25.43,24.93,-0.0286485791986055,0.869353521559041,"*",0.801488,"CFAP36","GO:0005634//nucleus;GO:0042995//cell projection;GO:0005737//cytoplasm","NA","NA","K16742//ADP-ribosylation factor-like protein 2-binding protein","NP_001269690.1//cilia- and flagella-associated protein 36 isoform a [Homo sapiens];NP_542398.3//cilia- and flagella-associated protein 36 isoform b [Homo sapiens]","6;1//3"]
[28511,2352,55.11,54.03,-0.0285534452050735,0.647349116859122,"*",0.526422,"NKIRAS2","GO:0016020//membrane;GO:0005622//intracellular;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0002039//p53 binding;GO:0008270//zinc ion binding;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:0007165//signal transduction;GO:0007249//I-kappaB kinase/NF-kappaB signaling","K17197//NF-kappa-B inhibitor-interacting Ras-like protein","OWK15227.1//NKIRAS2 [Cervus elaphus hippelaphus];NP_001138400.1//NF-kappa-B inhibitor-interacting Ras-like protein 2 isoform b [Homo sapiens];NP_060065.2//NF-kappa-B inhibitor-interacting Ras-like protein 2 isoform a [Homo sapiens]","1//3;2//1;5"]
[51421,5003,24.08,23.61,-0.0284373505310595,0.736766675767918,"*",0.635158,"AMOTL2","GO:0016324//apical plasma membrane;GO:0005829//cytosol;GO:0005923//bicellular tight junction;GO:0055037//recycling endosome","GO:0042802//identical protein binding","GO:0035329//hippo signaling;GO:0016055//Wnt signaling pathway","K06104//angiomotin like","NP_001265612.1//angiomotin-like protein 2 isoform 1 [Homo sapiens];BAD97318.1//Angiomotin like 2 (Fragment) variant, partial [Homo sapiens]","1//3;3//A2MP1"]
[378,1758,80.84,79.27,-0.0282943453228974,0.718865672175078,"*",0.60456,"ARF4","NA","NA","NA","K07939//ADP-ribosylation factor 4","ELK07801.1//ADP-ribosylation factor 4 [Pteropus alecto]","3//A2MP1"]
[25841,4919,8.8,8.63,-0.0281429643457046,0.857430989686497,"*",0.78588,"ABTB2","NA","NA","NA","K10521//ankyrin repeat and BTB/POZ domain-containing protein 2","EAW68173.1//ankyrin repeat and BTB (POZ) domain containing 2, isoform CRA_b [Homo sapiens]","2//1"]
[2760,3675,17.2,16.87,-0.0279485913018944,0.612417594088504,"*",0.456572,"GM2A","GO:0070062//extracellular exosome;GO:0045179//apical cortex;GO:0035578//azurophil granule lumen;GO:0043202//lysosomal lumen;GO:0005576//extracellular region;GO:0009898//cytoplasmic side of plasma membrane;GO:0005739//mitochondrion;GO:0005889//hydrogen:potassium-exchanging ATPase complex","GO:0005319//lipid transporter activity;GO:0004563//beta-N-acetylhexosaminidase activity;GO:0016004//phospholipase activator activity;GO:0030290//sphingolipid activator protein activity;GO:0008047//enzyme activator activity;GO:0032428//beta-N-acetylgalactosaminidase activity","GO:0051345//positive regulation of hydrolase activity;GO:0006687//glycosphingolipid metabolic process;GO:0009313//oligosaccharide catabolic process;GO:0019915//lipid storage;GO:0043312//neutrophil degranulation;GO:0050885//neuromuscular process controlling balance;GO:0006689//ganglioside catabolic process;GO:0007611//learning or memory","K12383//ganglioside GM2 activator","CAA43408.1//GM2-activator protein, partial [Homo sapiens];NP_001161079.1//ganglioside GM2 activator isoform 2 precursor [Homo sapiens]","4;1//3"]
[2055,7185,4.17,4.09,-0.0279465405029148,0.883441687124435,"*",0.819122,"CLN8","GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005789//endoplasmic reticulum membrane","NA","GO:0007399//nervous system development;GO:0045861//negative regulation of proteolysis;GO:0008203//cholesterol metabolic process;GO:0006869//lipid transport;GO:0030163//protein catabolic process;GO:0006672//ceramide metabolic process;GO:0006644//phospholipid metabolic process;GO:0046513//ceramide biosynthetic process;GO:0008610//lipid biosynthetic process","K12360//ceroid-lipofuscinosis neuronal protein 8","AAI36826.1//Ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) [Homo sapiens]","3//A2MP1"]
[55819,2272,20.36,19.97,-0.0279032286317228,0.845740229050663,"*",0.770188,"RNF130","NA","NA","NA","K15701//E3 ubiquitin-protein ligase RNF130 [EC:2.3.2.27]","XP_008013728.1//PREDICTED: E3 ubiquitin-protein ligase RNF130 isoform X3 [Chlorocebus sabaeus];XP_008013726.1//PREDICTED: E3 ubiquitin-protein ligase RNF130 isoform X1 [Chlorocebus sabaeus]","1//3;5"]
[56905,4443,28.23,27.69,-0.0278640750827626,0.73362160279761,"*",0.63038,"C15orf39","GO:0005829//cytosol","NA","NA","K10955//mucin-2;K09993//cyclin-dependent kinase inhibitor 1C","NP_056307.2//uncharacterized protein C15orf39 [Homo sapiens]",4]
[9662,5760,1.57,1.54,-0.0278342081967255,0.950691723313407,"*",0.905996,"CEP135","GO:0005814//centriole;GO:0005829//cytosol;GO:0005813//centrosome","GO:0008022//protein C-terminus binding","GO:0010389//regulation of G2/M transition of mitotic cell cycle;GO:1902857//positive regulation of non-motile cilium assembly;GO:0097711//ciliary basal body-plasma membrane docking;GO:0007099//centriole replication;GO:0000086//G2/M transition of mitotic cell cycle;GO:0010457//centriole-centriole cohesion","K16461//centrosomal protein CEP135","NP_079285.2//centrosomal protein of 135 kDa [Homo sapiens]",4]
[78987,2546,5.25,5.15,-0.0277449904829042,0.733780025641026,"*",0.630608,"CRELD1","GO:0016021//integral component of membrane","GO:0005509//calcium ion binding","GO:0003197//endocardial cushion development;GO:0003279//cardiac septum development","K08023//latent transforming growth factor beta binding protein 2/3/4;K17675//ATP-dependent RNA helicase SUPV3L1/SUV3 [EC:3.6.4.13]","NP_001026887.1//cysteine-rich with EGF-like domain protein 1 isoform 1 precursor [Homo sapiens];XP_001150237.2//PREDICTED: cysteine-rich with EGF-like domain protein 1 isoform X1 [Pan troglodytes]","4;3//A2MP1;2//1"]
[2107,3714,55.75,54.69,-0.0276947429347391,0.501231632951367,"*",0.347762,"ETF1","GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0008079//translation termination factor activity;GO:0043022//ribosome binding;GO:0003723//RNA binding;GO:1990825//sequence-specific mRNA binding;GO:0003747//translation release factor activity","GO:0006449//regulation of translational termination;GO:0006415//translational termination;GO:0006479//protein methylation;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0016032//viral process","K03265//peptide chain release factor subunit 1","XP_003215303.2//PREDICTED: eukaryotic peptide chain release factor subunit 1 [Anolis carolinensis];XP_014440263.1//PREDICTED: eukaryotic peptide chain release factor subunit 1 isoform X1 [Tupaia chinensis];NP_001269114.1//eukaryotic peptide chain release factor subunit 1 isoform 3 [Homo sapiens];XP_013204962.1//PREDICTED: eukaryotic peptide chain release factor subunit 1 isoform X1 [Microtus ochrogaster];XP_006204645.1//PREDICTED: eukaryotic peptide chain release factor subunit 1 [Vicugna pacos]","1//3;3//A2MP1"]
[41,3873,5.82,5.71,-0.0275284075454411,0.883106413182954,"*",0.81859,"ASIC1","GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0045202//synapse;GO:0005886//plasma membrane","GO:0022839//ion gated channel activity;GO:0044736//acid-sensing ion channel activity;GO:0015280//ligand-gated sodium channel activity","GO:0006810//transport;GO:0070588//calcium ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0007165//signal transduction;GO:0009268//response to pH;GO:0034220//ion transmembrane transport;GO:0071467//cellular response to pH;GO:0007613//memory;GO:0010447//response to acidic pH;GO:0008306//associative learning;GO:0006814//sodium ion transport;GO:0050915//sensory perception of sour taste;GO:0046929//negative regulation of neurotransmitter secretion;GO:0070207//protein homotrimerization;GO:0042391//regulation of membrane potential","K04829//acid-sensing ion channel 1","NP_001243759.1//acid-sensing ion channel 1 isoform c [Homo sapiens];NP_064423.2//acid-sensing ion channel 1 isoform a [Homo sapiens];XP_004778896.1//PREDICTED: acid-sensing ion channel 1 isoform X3 [Mustela putorius furo]","1//3;3//A2MP1"]
[79863,5679,6.92,6.79,-0.0273604633919929,0.866364169952413,"*",0.79781,"RBFA","GO:0005739//mitochondrion","NA","GO:0006364//rRNA processing","NA","NP_001165438.1//putative ribosome-binding factor A, mitochondrial isoform 2 precursor [Homo sapiens];NP_079081.2//putative ribosome-binding factor A, mitochondrial isoform 1 precursor [Homo sapiens]","1//3;2//1"]
[11253,2787,22.94,22.51,-0.0272993345616693,0.817544319443478,"*",0.735708,"MAN1B1","GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:1903561//extracellular vesicle;GO:0044322//endoplasmic reticulum quality control compartment;GO:0000139//Golgi membrane","GO:0004571//mannosyl-oligosaccharide 1,2-alpha-mannosidase activity;GO:0005509//calcium ion binding","GO:0006486//protein glycosylation;GO:0036508//protein alpha-1,2-demannosylation;GO:1904380//endoplasmic reticulum mannose trimming;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0036511//trimming of first mannose on A branch;GO:0006491//N-glycan processing;GO:1904382//mannose trimming involved in glycoprotein ERAD pathway;GO:0036512//trimming of second mannose on A branch;GO:0009311//oligosaccharide metabolic process;GO:0036510//trimming of terminal mannose on C branch;GO:0036509//trimming of terminal mannose on B branch","K01230//mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]","NP_057303.2//endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase [Homo sapiens]",4]
[5094,3163,176.82,173.51,-0.0272626534364785,0.469193406022654,"*",0.318954,"PCBP2","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005925//focal adhesion;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030529//intracellular ribonucleoprotein complex","GO:0003723//RNA binding;GO:0003677//DNA binding;GO:1990829//C-rich single-stranded DNA binding;GO:0031625//ubiquitin protein ligase binding;GO:0019899//enzyme binding","GO:0016070//RNA metabolic process;GO:0075522//IRES-dependent viral translational initiation;GO:0000398//mRNA splicing, via spliceosome;GO:0051607//defense response to virus;GO:0050687//negative regulation of defense response to virus;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0039694//viral RNA genome replication;GO:0016071//mRNA metabolic process;GO:0032480//negative regulation of type I interferon production;GO:0045087//innate immune response","K13162//poly(rC)-binding protein 2","NP_001122385.1//poly(rC)-binding protein 2 isoform f [Homo sapiens];BAD92062.1//poly(rC)-binding protein 2 isoform b variant, partial [Homo sapiens];NP_001122386.1//poly(rC)-binding protein 2 isoform g [Homo sapiens]","4;1//3;2//1;5"]
[10910,1810,12.87,12.63,-0.0271574144331494,0.884287702584171,"*",0.82046,"SUGT1","GO:0005634//nucleus;GO:0000151//ubiquitin ligase complex;GO:0043234//protein complex;GO:0005829//cytosol;GO:0000776//kinetochore","NA","GO:0000278//mitotic cell cycle;GO:0043947//positive regulation by host of symbiont catalytic activity;GO:0031647//regulation of protein stability","K12795//suppressor of G2 allele of SKP1","NP_001307760.1//protein SGT1 homolog isoform C [Homo sapiens];NP_006695.1//protein SGT1 homolog isoform A [Homo sapiens];NP_001124384.1//protein SGT1 homolog isoform B [Homo sapiens]","1//3;4;2//1"]
[1462,4193,5.37,5.27,-0.0271191263481981,{"v":6.74860867106796e-07,"d":"6.75E-07"},"*",{"v":1.087872E-7,"d":"1.09E-07"},"VCAN","GO:0016020//membrane;GO:0031012//extracellular matrix;GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0005578//proteinaceous extracellular matrix;GO:0005796//Golgi lumen;GO:0005576//extracellular region;GO:0043202//lysosomal lumen","GO:0005201//extracellular matrix structural constituent;GO:0030246//carbohydrate binding;GO:0005509//calcium ion binding;GO:0005539//glycosaminoglycan binding;GO:0005540//hyaluronic acid binding","GO:0043687//post-translational protein modification;GO:0001649//osteoblast differentiation;GO:0030208//dermatan sulfate biosynthetic process;GO:0030206//chondroitin sulfate biosynthetic process;GO:0007417//central nervous system development;GO:0044267//cellular protein metabolic process;GO:0007155//cell adhesion;GO:0008347//glial cell migration;GO:0030198//extracellular matrix organization;GO:0007275//multicellular organism development;GO:0030207//chondroitin sulfate catabolic process;GO:0008037//cell recognition;GO:0001501//skeletal system development;GO:0030203//glycosaminoglycan metabolic process","K06793//versican core protein","NP_001157569.1//versican core protein isoform 3 precursor [Homo sapiens];NP_001157570.1//versican core protein isoform 4 precursor [Homo sapiens];NP_001119808.1//versican core protein isoform 2 precursor [Homo sapiens];BAD92728.1//chondroitin sulfate proteoglycan 2 (versican) variant, partial [Homo sapiens]","4;1//3;2//1"]
[10956,2771,50.68,49.74,-0.0270100169239029,0.458892148010758,"*",0.309768,"OS9","GO:0005788//endoplasmic reticulum lumen;GO:0000836//Hrd1p ubiquitin ligase complex;GO:0005789//endoplasmic reticulum membrane;GO:0044322//endoplasmic reticulum quality control compartment","GO:0002020//protease binding;GO:0030246//carbohydrate binding","GO:0006605//protein targeting;GO:0030970//retrograde protein transport, ER to cytosol;GO:0055085//transmembrane transport;GO:1904380//endoplasmic reticulum mannose trimming;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0034976//response to endoplasmic reticulum stress;GO:0016567//protein ubiquitination;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0006621//protein retention in ER lumen;GO:1904153//negative regulation of retrograde protein transport, ER to cytosol","K10088//protein OS-9","NP_001017957.1//protein OS-9 isoform 3 precursor [Homo sapiens];NP_001248351.1//protein OS-9 isoform 7 precursor [Homo sapiens];NP_001248352.1//protein OS-9 isoform 8 precursor [Homo sapiens];NP_001248349.1//protein OS-9 isoform 5 precursor [Homo sapiens];NP_001248350.1//protein OS-9 isoform 6 precursor [Homo sapiens];NP_006803.1//protein OS-9 isoform 1 precursor [Homo sapiens];NP_001017956.1//protein OS-9 isoform 2 precursor [Homo sapiens];NP_001017958.1//protein OS-9 isoform 4 precursor [Homo sapiens]","1//3;3//A2MP1;2//1"]
[7170,3170,183.74,180.35,-0.0268663106711749,0.121210910949663,"*",0.0584884,"TPM3","GO:0005856//cytoskeleton;GO:0070062//extracellular exosome;GO:0005884//actin filament;GO:0001725//stress fiber;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0005862//muscle thin filament tropomyosin","GO:0051015//actin filament binding;GO:0008307//structural constituent of muscle","GO:0006928//movement of cell or subcellular component;GO:0007015//actin filament organization;GO:0030049//muscle filament sliding;GO:0006936//muscle contraction","K09290//tropomyosin 3","XP_007186605.1//PREDICTED: tropomyosin alpha-3 chain-like isoform X2 [Balaenoptera acutorostrata scammoni];NP_001036817.1//tropomyosin alpha-3 chain isoform Tpm3.7cy [Homo sapiens];NP_001036818.1//tropomyosin alpha-3 chain isoform Tpm3.4cy [Homo sapiens];XP_007186604.1//PREDICTED: tropomyosin alpha-3 chain-like isoform X1 [Balaenoptera acutorostrata scammoni];XP_021052495.1//tropomyosin alpha-3 chain isoform X9 [Mus pahari];XP_008853322.1//PREDICTED: tropomyosin alpha-3 chain isoform X11 [Nannospalax galili];NP_001036816.1//tropomyosin alpha-3 chain isoform Tpm3.2cy [Homo sapiens];XP_017650578.1//PREDICTED: tropomyosin alpha-3 chain isoform X2 [Nannospalax galili];XP_008853313.1//PREDICTED: tropomyosin alpha-3 chain isoform X12 [Nannospalax galili]","1//3;3//A2MP1"]
[9647,5199,11.97,11.75,-0.0267623954911399,0.830455834900443,"*",0.751954,"PPM1F","GO:0043234//protein complex;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm","GO:0046872//metal ion binding;GO:0004722//protein serine/threonine phosphatase activity;GO:0016791//phosphatase activity;GO:0033192//calmodulin-dependent protein phosphatase activity","GO:0035690//cellular response to drug;GO:0016576//histone dephosphorylation;GO:0010634//positive regulation of epithelial cell migration;GO:0035970//peptidyl-threonine dephosphorylation;GO:0097193//intrinsic apoptotic signaling pathway;GO:0010811//positive regulation of cell-substrate adhesion;GO:0045927//positive regulation of growth;GO:0045892//negative regulation of transcription, DNA-templated;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0051894//positive regulation of focal adhesion assembly;GO:0010628//positive regulation of gene expression;GO:0006469//negative regulation of protein kinase activity;GO:0051496//positive regulation of stress fiber assembly;GO:0050921//positive regulation of chemotaxis;GO:0044387//negative regulation of protein kinase activity by regulation of protein phosphorylation","K17502//protein phosphatase 1F [EC:3.1.3.16]","NP_055449.1//protein phosphatase 1F [Homo sapiens]","3//A2MP1"]
[84811,2216,10.34,10.15,-0.0267564582423959,0.909171180919294,"*",0.851914,"BUD13","GO:0005634//nucleus;GO:0070274//RES complex","GO:0003723//RNA binding","GO:0006406//mRNA export from nucleus;GO:0000398//mRNA splicing, via spliceosome","K13106//pre-mRNA-splicing factor CWC26","NP_116114.1//BUD13 homolog isoform 1 [Homo sapiens];NP_001153208.1//BUD13 homolog isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[1856,3046,28.35,27.83,-0.026707826497984,0.789413630812721,"*",0.699274,"DVL2","NA","NA","NA","K02353//segment polarity protein dishevelled","XP_003810156.1//PREDICTED: segment polarity protein dishevelled homolog DVL-2 isoform X1 [Pan paniscus]","2//1"]
[57019,2184,33.92,33.3,-0.0266139926045749,0.891469515265635,"*",0.829858,"CIAPIN1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005758//mitochondrial intermembrane space;GO:0005739//mitochondrion;GO:0005737//cytoplasm","GO:0009055//electron transfer activity;GO:0046872//metal ion binding;GO:0051537//2 iron, 2 sulfur cluster binding;GO:0008168//methyltransferase activity;GO:0051536//iron-sulfur cluster binding","GO:0016226//iron-sulfur cluster assembly;GO:0043066//negative regulation of apoptotic process;GO:0030097//hemopoiesis;GO:0006915//apoptotic process","NA","NP_001295287.1//anamorsin isoform 3 [Homo sapiens];NP_001295276.1//anamorsin isoform 2 [Homo sapiens];NP_064709.2//anamorsin isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[3654,3444,150.99,148.25,-0.0264208988973299,0.586587301825627,"*",0.430448,"IRAK1","GO:0010008//endosome membrane;GO:0005634//nucleus;GO:0005811//lipid droplet;GO:0045323//interleukin-1 receptor complex;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0031072//heat shock protein binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0004704//NF-kappaB-inducing kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004672//protein kinase activity","GO:0060337//type I interferon signaling pathway;GO:0032481//positive regulation of type I interferon production;GO:0070498//interleukin-1-mediated signaling pathway;GO:0034134//toll-like receptor 2 signaling pathway;GO:0001959//regulation of cytokine-mediated signaling pathway;GO:0070555//response to interleukin-1;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0051259//protein oligomerization;GO:0007165//signal transduction;GO:0070423//nucleotide-binding oligomerization domain containing signaling pathway;GO:0006468//protein phosphorylation;GO:0007250//activation of NF-kappaB-inducing kinase activity;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0046777//protein autophosphorylation;GO:0071456//cellular response to hypoxia;GO:0032496//response to lipopolysaccharide;GO:0035556//intracellular signal transduction;GO:0045893//positive regulation of transcription, DNA-templated;GO:0034162//toll-like receptor 9 signaling pathway;GO:0034142//toll-like receptor 4 signaling pathway;GO:0000187//activation of MAPK activity;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0043406//positive regulation of MAP kinase activity;GO:0034605//cellular response to heat;GO:0002224//toll-like receptor signaling pathway;GO:0007254//JNK cascade;GO:0007568//aging;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0002755//MyD88-dependent toll-like receptor signaling pathway","K04730//interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]","NP_001020414.1//interleukin-1 receptor-associated kinase 1 isoform 3 [Homo sapiens];NP_001560.2//interleukin-1 receptor-associated kinase 1 isoform 1 [Homo sapiens];NP_001020413.1//interleukin-1 receptor-associated kinase 1 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[4125,3231,13.81,13.56,-0.026356141121707,0.859533209327697,"*",0.789152,"MAN2B1","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0035578//azurophil granule lumen;GO:0043202//lysosomal lumen;GO:0005576//extracellular region","GO:0046872//metal ion binding;GO:0030246//carbohydrate binding;GO:0004559//alpha-mannosidase activity","GO:0009313//oligosaccharide catabolic process;GO:0006013//mannose metabolic process;GO:0006464//cellular protein modification process;GO:0043312//neutrophil degranulation;GO:0006517//protein deglycosylation","K12311//lysosomal alpha-mannosidase [EC:3.2.1.24]","NP_000519.2//lysosomal alpha-mannosidase isoform 1 precursor [Homo sapiens];NP_001166969.1//lysosomal alpha-mannosidase isoform 2 precursor [Homo sapiens]","1//3;3//A2MP1"]
[7023,2147,15.47,15.19,-0.0263513269469523,0.89035388700565,"*",0.828708,"TFAP4","NA","GO:0046983//protein dimerization activity","NA","K09108//transcription factor AP-4","CAG46527.1//TFAP4 [Homo sapiens]","2//1"]
[84440,8277,1.12,1.1,-0.0259952085329446,0.794715795725471,"*",0.705314,"RAB11FIP4","GO:0043231//intracellular membrane-bounded organelle;GO:0005815//microtubule organizing center;GO:0005615//extracellular space;GO:0048471//perinuclear region of cytoplasm;GO:0030496//midbody;GO:0005768//endosome;GO:0055038//recycling endosome membrane;GO:0032154//cleavage furrow;GO:0030139//endocytic vesicle;GO:0005819//spindle","GO:0005509//calcium ion binding;GO:0030306//ADP-ribosylation factor binding;GO:0017137//Rab GTPase binding;GO:0042803//protein homodimerization activity","GO:0006810//transport;GO:0003407//neural retina development;GO:0000910//cytokinesis;GO:0016032//viral process;GO:1903452//positive regulation of G1 to G0 transition","K12485//Rab11 family-interacting protein 3/4","XP_014197570.1//PREDICTED: rab11 family-interacting protein 4 isoform X3 [Pan paniscus];XP_018883627.1//PREDICTED: rab11 family-interacting protein 4 isoform X1 [Gorilla gorilla gorilla];XP_003953123.2//PREDICTED: rab11 family-interacting protein 4 isoform X2 [Pan troglodytes];XP_003812026.1//PREDICTED: rab11 family-interacting protein 4 isoform X1 [Pan paniscus];NP_116321.2//rab11 family-interacting protein 4 isoform 1 [Homo sapiens]","1//3;2//1;5"]
[219931,5026,3.92,3.85,-0.0259952085329444,0.926867285107513,"*",0.874298,"TPCN2","GO:0005765//lysosomal membrane;GO:0010008//endosome membrane;GO:0016021//integral component of membrane;GO:0005764//lysosome;GO:0005886//plasma membrane","GO:0072345//NAADP-sensitive calcium-release channel activity;GO:0005245//voltage-gated calcium channel activity;GO:0042802//identical protein binding;GO:0019901//protein kinase binding","GO:0034220//ion transmembrane transport;GO:0006939//smooth muscle contraction;GO:0019722//calcium-mediated signaling;GO:0033280//response to vitamin D;GO:0086010//membrane depolarization during action potential;GO:0010506//regulation of autophagy;GO:0006874//cellular calcium ion homeostasis;GO:0007040//lysosome organization","K14077//two pore calcium channel protein 2","NP_620714.2//two pore calcium channel protein 2 [Homo sapiens]","3//A2MP1"]
[64708,2501,30.34,29.8,-0.0259087548975095,0.693615936732696,"*",0.576508,"COPS7B","GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0008180//COP9 signalosome","NA","GO:0043687//post-translational protein modification;GO:0000338//protein deneddylation;GO:0000715//nucleotide-excision repair, DNA damage recognition;GO:0006283//transcription-coupled nucleotide-excision repair","K12180//COP9 signalosome complex subunit 7","XP_017198683.1//PREDICTED: COP9 signalosome complex subunit 7b [Oryctolagus cuniculus];XP_012414900.1//PREDICTED: COP9 signalosome complex subunit 7b isoform X4 [Trichechus manatus latirostris];XP_009442824.1//PREDICTED: COP9 signalosome complex subunit 7b isoform X4 [Pan troglodytes];XP_021779815.1//COP9 signalosome complex subunit 7b isoform X1 [Papio anubis];XP_021513817.1//COP9 signalosome complex subunit 7b isoform X1 [Meriones unguiculatus]","1//3;3//A2MP1;2//1"]
[83787,2492,18.66,18.33,-0.0257422003118731,0.760179274717361,"*",0.660862,"ARMC10","GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005789//endoplasmic reticulum membrane","GO:0050692//DBD domain binding;GO:0002039//p53 binding","GO:0040010//positive regulation of growth rate;GO:1902254//negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator;GO:0040008//regulation of growth;GO:0043066//negative regulation of apoptotic process","K11447//histone demethylase [EC:1.14.11.-];K15696//RING finger protein 113B;K17985//activating molecule in BECN1-regulated autophagy protein 1;K10279//F-box and leucine-rich repeat protein 13","NP_001154481.1//armadillo repeat-containing protein 10 isoform b [Homo sapiens];NP_001154484.1//armadillo repeat-containing protein 10 isoform d [Homo sapiens];NP_001154485.1//armadillo repeat-containing protein 10 isoform f [Homo sapiens];NP_001154483.1//armadillo repeat-containing protein 10 isoform e [Homo sapiens];XP_008962092.1//PREDICTED: armadillo repeat-containing protein 10 [Pan paniscus];NP_001154482.1//armadillo repeat-containing protein 10 isoform c [Homo sapiens]","4;2//1"]
[5433,2338,23.86,23.44,-0.02562147327298,0.848134519300651,"*",0.774386,"POLR2D","GO:0005665//DNA-directed RNA polymerase II, core complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0000932//P-body","GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0000166//nucleotide binding;GO:0031369//translation initiation factor binding","GO:0042795//snRNA transcription from RNA polymerase II promoter;GO:0006370//7-methylguanosine mRNA capping;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0035019//somatic stem cell population maintenance;GO:0045948//positive regulation of translational initiation;GO:0031990//mRNA export from nucleus in response to heat stress;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0016070//RNA metabolic process;GO:0000398//mRNA splicing, via spliceosome;GO:0060964//regulation of gene silencing by miRNA;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0050434//positive regulation of viral transcription;GO:0006351//transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter;GO:0034402//recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex;GO:0006367//transcription initiation from RNA polymerase II promoter","K03012//DNA-directed RNA polymerase II subunit RPB4","NP_004796.1//DNA-directed RNA polymerase II subunit RPB4 [Homo sapiens]","3//A2MP1"]
[84978,4951,1.15,1.13,-0.0253110885291875,0.930077546171694,"*",0.878316,"FRMD5","GO:0005856//cytoskeleton;GO:0016021//integral component of membrane;GO:0005912//adherens junction","GO:0005178//integrin binding;GO:0008092//cytoskeletal protein binding;GO:0005200//structural constituent of cytoskeleton;GO:0019901//protein kinase binding","GO:0031032//actomyosin structure organization;GO:0030334//regulation of cell migration;GO:0045785//positive regulation of cell adhesion;GO:2000146//negative regulation of cell motility","K18037//tyrosine-protein phosphatase non-receptor type 4 [EC:3.1.3.48];K06107//erythrocyte membrane protein band 4.1","XP_019500572.1//PREDICTED: FERM domain-containing protein 5 isoform X2 [Hipposideros armiger];NP_001309880.1//FERM domain-containing protein 5 isoform 8 [Homo sapiens];NP_001273420.1//FERM domain-containing protein 5 isoform 4 [Homo sapiens];XP_011920534.1//PREDICTED: FERM domain-containing protein 5 isoform X13 [Cercocebus atys];NP_001309878.1//FERM domain-containing protein 5 isoform 6 [Homo sapiens];NP_116281.2//FERM domain-containing protein 5 isoform 2 [Homo sapiens]","4;1//3"]
[80759,1388,2.31,2.27,-0.0252005541251425,0.890465897639384,"*",0.828868,"KHDC1","GO:0016021//integral component of membrane","GO:0003723//RNA binding","NA","K00658//2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]","NP_001238803.1//KH homology domain-containing protein 1 isoform 1 [Homo sapiens]","1//3;4"]
[8729,6440,17.93,17.62,-0.025161563947961,0.777796853871476,"*",0.680414,"GBF1","GO:0016020//membrane;GO:0005788//endoplasmic reticulum lumen;GO:0031252//cell leading edge;GO:0005777//peroxisome;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005802//trans-Golgi network;GO:0005801//cis-Golgi network;GO:0000139//Golgi membrane;GO:0005795//Golgi stack;GO:0005811//lipid droplet;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0005739//mitochondrion","GO:0080025//phosphatidylinositol-3,5-bisphosphate binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005086//ARF guanyl-nucleotide exchange factor activity","GO:1903409//reactive oxygen species biosynthetic process;GO:0007346//regulation of mitotic cell cycle;GO:0034067//protein localization to Golgi apparatus;GO:0006895//Golgi to endosome transport;GO:0061162//establishment of monopolar cell polarity;GO:2000008//regulation of protein localization to cell surface;GO:0097111//endoplasmic reticulum-Golgi intermediate compartment organization;GO:0048205//COPI coating of Golgi vesicle;GO:0002263//cell activation involved in immune response;GO:0015031//protein transport;GO:0090166//Golgi disassembly;GO:0030593//neutrophil chemotaxis;GO:0042147//retrograde transport, endosome to Golgi;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0007030//Golgi organization;GO:0016032//viral process;GO:1903420//protein localization to endoplasmic reticulum tubular network;GO:0032012//regulation of ARF protein signal transduction;GO:0006892//post-Golgi vesicle-mediated transport;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0098586//cellular response to virus;GO:0070973//protein localization to endoplasmic reticulum exit site","K18443//golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1","NP_004184.1//Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 isoform 1 [Homo sapiens];NP_001186308.1//Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 isoform 3 [Homo sapiens];NP_001186307.1//Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 isoform 2 [Homo sapiens]","1//3;2//1"]
[84842,1803,2.32,2.28,-0.0250909809628302,0.968619857049693,"*",0.929812,"HPDL","NA","GO:0046872//metal ion binding;GO:0003868//4-hydroxyphenylpyruvate dioxygenase activity;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0051213//dioxygenase activity","GO:0009072//aromatic amino acid family metabolic process","K00457//4-hydroxyphenylpyruvate dioxygenase [EC:1.13.11.27]","NP_116145.1//4-hydroxyphenylpyruvate dioxygenase-like protein [Homo sapiens]","2//1"]
[286319,2477,5.81,5.71,-0.0250474180416862,0.937768261380905,"*",0.888514,"TUSC1","NA","NA","NA","K16628//collagen, type VII, alpha;K07604//type I keratin, acidic","NP_001004125.1//tumor suppressor candidate gene 1 protein [Homo sapiens]","2//1"]
[284565,4802,15.13,14.87,-0.0250073401643186,0.819822571249913,"*",0.738682,"NBPF15","GO:0005737//cytoplasm","NA","NA","K22244//regenerating islet-derived protein 4;K05759//profilin;K16549//myomegalin","NP_775909.2//neuroblastoma breakpoint family member 15 [Homo sapiens]","4;2//1"]
[8089,1467,22.14,21.76,-0.0249766655312127,0.656185012809695,"*",0.535538,"YEATS4","GO:0035267//NuA4 histone acetyltransferase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0016363//nuclear matrix","GO:0003677//DNA binding;GO:0008022//protein C-terminus binding;GO:0005200//structural constituent of cytoskeleton;GO:0003700//DNA binding transcription factor activity","GO:0000278//mitotic cell cycle;GO:0006355//regulation of transcription, DNA-templated;GO:0040008//regulation of growth;GO:0043968//histone H2A acetylation;GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0043967//histone H4 acetylation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter","K11341//YEATS domain-containing protein 4","NP_006521.1//YEATS domain-containing protein 4 isoform 1 [Homo sapiens];NP_001287879.1//YEATS domain-containing protein 4 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[9913,4609,18.07,17.76,-0.0249649245144936,0.774838594238211,"*",0.676856,"SUPT7L","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0030914//STAGA complex","GO:0003713//transcription coactivator activity;GO:0004402//histone acetyltransferase activity","GO:0043966//histone H3 acetylation;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0051457//maintenance of protein location in nucleus","K11316//STAGA complex 65 subunit gamma","NP_055675.1//STAGA complex 65 subunit gamma isoform a [Homo sapiens];NP_001269659.1//STAGA complex 65 subunit gamma isoform b [Homo sapiens];NP_001269661.1//STAGA complex 65 subunit gamma isoform c [Homo sapiens]","1//3;2//1"]
[403,3891,8.17,8.03,-0.0249360906283691,0.888228447379059,"*",0.825284,"ARL3","GO:0070062//extracellular exosome;GO:0005929//cilium;GO:0005634//nucleus;GO:0032391//photoreceptor connecting cilium;GO:0005881//cytoplasmic microtubule;GO:0005622//intracellular;GO:0005813//centrosome;GO:0030496//midbody;GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005876//spindle microtubule","GO:0046872//metal ion binding;GO:0019003//GDP binding;GO:0005525//GTP binding;GO:0008017//microtubule binding;GO:0003924//GTPase activity","GO:0000281//mitotic cytokinesis;GO:0060271//cilium assembly;GO:0042073//intraciliary transport;GO:0001822//kidney development;GO:0007264//small GTPase mediated signal transduction;GO:0042461//photoreceptor cell development;GO:0006892//post-Golgi vesicle-mediated transport;GO:0007224//smoothened signaling pathway;GO:0015031//protein transport","K07944//ADP-ribosylation factor-like protein 3","XP_012658993.1//PREDICTED: ADP-ribosylation factor-like protein 3 [Otolemur garnettii]","3//A2MP1"]
[7555,3380,76.47,75.16,-0.0249288073233024,0.678617080736866,"*",0.560388,"CNBP","GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol","GO:0003723//RNA binding;GO:0003676//nucleic acid binding;GO:0001227//transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0003697//single-stranded DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0008270//zinc ion binding;GO:0003700//DNA binding transcription factor activity;GO:0003727//single-stranded RNA binding","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006355//regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006695//cholesterol biosynthetic process;GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0008284//positive regulation of cell proliferation","K09250//cellular nucleic acid-binding protein","ELK15208.1//Cellular nucleic acid-binding protein [Pteropus alecto];NP_001120664.1//cellular nucleic acid-binding protein isoform 1 [Homo sapiens];EDK99231.1//cellular nucleic acid binding protein, isoform CRA_d, partial [Mus musculus]","4;1//3"]
[5871,3027,8.26,8.12,-0.0246620542342692,0.915415643508959,"*",0.860344,"MAP4K2","GO:0016323//basolateral plasma membrane;GO:0005622//intracellular;GO:0005737//cytoplasm;GO:0000139//Golgi membrane","GO:0004674//protein serine/threonine kinase activity;GO:0008349//MAP kinase kinase kinase kinase activity;GO:0005524//ATP binding;GO:0031435//mitogen-activated protein kinase kinase kinase binding","GO:0046330//positive regulation of JNK cascade;GO:0007346//regulation of mitotic cell cycle;GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction;GO:0007254//JNK cascade;GO:0007257//activation of JUN kinase activity;GO:0006903//vesicle targeting;GO:0006955//immune response;GO:0031098//stress-activated protein kinase signaling cascade;GO:0045087//innate immune response;GO:0042981//regulation of apoptotic process","K04414//mitogen-activated protein kinase kinase kinase kinase 2 [EC:2.7.11.1]","NP_004570.2//mitogen-activated protein kinase kinase kinase kinase 2 isoform 1 [Homo sapiens];NP_001294919.1//mitogen-activated protein kinase kinase kinase kinase 2 isoform 2 [Homo sapiens]","1//3;4"]
[26579,2473,87.12,85.65,-0.0245507077455455,0.625840413384291,"*",0.50231,"MYEOV","NA","NA","NA","NA","NP_620123.2//myeloma-overexpressed gene protein isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[3755,2237,4.19,4.12,-0.0243059065161332,0.95184272751149,"*",0.90751,"KCNG1","GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex","GO:0005249//voltage-gated potassium channel activity;GO:0005267//potassium channel activity;GO:0005251//delayed rectifier potassium channel activity","GO:0006813//potassium ion transport;GO:1902259//regulation of delayed rectifier potassium channel activity;GO:0051260//protein homooligomerization;GO:0071805//potassium ion transmembrane transport","K04900//potassium voltage-gated channel subfamily G member 1","NP_002228.2//potassium voltage-gated channel subfamily G member 1 [Homo sapiens]","3//A2MP1"]
[64976,1055,39.58,38.92,-0.0242599022664005,0.867880141886382,"*",0.799532,"MRPL40","GO:0005634//nucleus;GO:0005761//mitochondrial ribosome;GO:0005762//mitochondrial large ribosomal subunit;GO:0005743//mitochondrial inner membrane","GO:0003723//RNA binding","GO:0009653//anatomical structure morphogenesis;GO:0070126//mitochondrial translational termination;GO:0070125//mitochondrial translational elongation","K17421//large subunit ribosomal protein L40","NP_003767.2//39S ribosomal protein L40, mitochondrial isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[27074,3341,0.6,0.59,-0.0242475462466774,0.940997344413666,"*",0.893164,"LAMP3","GO:0005765//lysosomal membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0031982//vesicle;GO:0048471//perinuclear region of cytoplasm;GO:0097233//alveolar lamellar body membrane;GO:0016021//integral component of membrane;GO:0005769//early endosome;GO:0005886//plasma membrane","NA","GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0035455//response to interferon-alpha;GO:1903900//regulation of viral life cycle;GO:0010506//regulation of autophagy;GO:0010628//positive regulation of gene expression;GO:1901799//negative regulation of proteasomal protein catabolic process;GO:0002250//adaptive immune response","K06562//lysosomal-associated membrane protein 3","NP_055213.2//lysosome-associated membrane glycoprotein 3 precursor [Homo sapiens]","3//A2MP1"]
[57001,2068,7.22,7.1,-0.0241798124951267,0.93919022823576,"*",0.890802,"SDHAF3","GO:0005759//mitochondrial matrix;GO:0005758//mitochondrial intermembrane space;GO:0005739//mitochondrion","NA","GO:0006979//response to oxidative stress;GO:0006105//succinate metabolic process;GO:0006111//regulation of gluconeogenesis;GO:0034553//mitochondrial respiratory chain complex II assembly","NA","NP_064571.1//succinate dehydrogenase assembly factor 3, mitochondrial precursor [Homo sapiens]","2//1"]
[3373,2352,1.81,1.78,-0.0241124561168077,0.969339317683881,"*",0.930624,"HYAL1","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0036117//hyaluranon cable;GO:0031410//cytoplasmic vesicle;GO:0043202//lysosomal lumen;GO:0005764//lysosome;GO:0005737//cytoplasm","GO:0008134//transcription factor binding;GO:0004415//hyalurononglucosaminidase activity;GO:0050501//hyaluronan synthase activity","GO:0060272//embryonic skeletal joint morphogenesis;GO:0045785//positive regulation of cell adhesion;GO:0030214//hyaluronan catabolic process;GO:0030307//positive regulation of cell growth;GO:0071356//cellular response to tumor necrosis factor;GO:0071467//cellular response to pH;GO:0051216//cartilage development;GO:0000302//response to reactive oxygen species;GO:0046677//response to antibiotic;GO:0010634//positive regulation of epithelial cell migration;GO:0071347//cellular response to interleukin-1;GO:0030213//hyaluronan biosynthetic process;GO:0030207//chondroitin sulfate catabolic process;GO:0005975//carbohydrate metabolic process;GO:0045766//positive regulation of angiogenesis;GO:0036120//cellular response to platelet-derived growth factor stimulus;GO:0045927//positive regulation of growth;GO:0071493//cellular response to UV-B;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle;GO:0030308//negative regulation of cell growth;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0006954//inflammatory response;GO:1900106//positive regulation of hyaluranon cable assembly;GO:0009615//response to virus;GO:0030212//hyaluronan metabolic process;GO:0050679//positive regulation of epithelial cell proliferation","K01197//hyaluronoglucosaminidase [EC:3.2.1.35]","NP_695014.1//hyaluronidase-1 isoform 2 precursor [Homo sapiens];NP_149349.2//hyaluronidase-1 isoform 1 precursor [Homo sapiens];AAD53277.1//hyaluronoglucosaminidase 1 isoform 2 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[55531,3029,1.21,1.19,-0.0240454739666511,0.963554935528121,"*",0.923442,"ELMOD1","GO:0005654//nucleoplasm;GO:0005829//cytosol","GO:0005096//GTPase activator activity","GO:0031647//regulation of protein stability;GO:1903955//positive regulation of protein targeting to mitochondrion","K12581//CCR4-NOT transcription complex subunit 7/8;K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K11447//histone demethylase [EC:1.14.11.-];K20092//chromodomain-helicase-DNA-binding protein 1-like [EC:3.6.4.12]","BAE21051.1//unnamed protein product, partial [Mus musculus];NP_061182.3//ELMO domain-containing protein 1 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[6236,1467,0.61,0.6,-0.0238467419543678,1.02066196741919,"*",0.996254,"RRAD","GO:0016020//membrane;GO:0005622//intracellular;GO:0005886//plasma membrane","GO:0005525//GTP binding;GO:0005516//calmodulin binding;GO:0003924//GTPase activity","GO:1901842//negative regulation of high voltage-gated calcium channel activity;GO:0007165//signal transduction;GO:0007264//small GTPase mediated signal transduction","K07845//Ras-related associated with diabetes","NP_004156.1//GTP-binding protein RAD [Homo sapiens]","1//3;2//1"]
[5467,3424,9.2,9.05,-0.0237160689738073,1.01180242028986,"*",0.978992,"PPARD","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000790//nuclear chromatin","GO:0003707//steroid hormone receptor activity;GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity;GO:0004879//nuclear receptor activity;GO:0001227//transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0008289//lipid binding;GO:0003713//transcription coactivator activity;GO:0051059//NF-kappaB binding;GO:0008144//drug binding;GO:0070539//linoleic acid binding;GO:0008270//zinc ion binding;GO:0043565//sequence-specific DNA binding;GO:0005504//fatty acid binding;GO:0008134//transcription factor binding","GO:0045684//positive regulation of epidermis development;GO:0043616//keratinocyte proliferation;GO:0097190//apoptotic signaling pathway;GO:0071222//cellular response to lipopolysaccharide;GO:0001890//placenta development;GO:0050728//negative regulation of inflammatory response;GO:0007566//embryo implantation;GO:0008366//axon ensheathment;GO:0008654//phospholipid biosynthetic process;GO:0009749//response to glucose;GO:0051546//keratinocyte migration;GO:0006776//vitamin A metabolic process;GO:0033189//response to vitamin A;GO:0046697//decidualization;GO:0030154//cell differentiation;GO:0015908//fatty acid transport;GO:0007507//heart development;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0009299//mRNA transcription;GO:0043066//negative regulation of apoptotic process;GO:2000288//positive regulation of myoblast proliferation;GO:0010628//positive regulation of gene expression;GO:0006915//apoptotic process;GO:0045662//negative regulation of myoblast differentiation;GO:1902894//negative regulation of pri-miRNA transcription from RNA polymerase II promoter;GO:0014842//regulation of skeletal muscle satellite cell proliferation;GO:0071456//cellular response to hypoxia;GO:0032024//positive regulation of insulin secretion;GO:0097755//positive regulation of blood vessel diameter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006635//fatty acid beta-oxidation;GO:0043415//positive regulation of skeletal muscle tissue regeneration;GO:0030308//negative regulation of cell growth;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0045598//regulation of fat cell differentiation;GO:0032966//negative regulation of collagen biosynthetic process;GO:0014823//response to activity;GO:0042060//wound healing;GO:0006351//transcription, DNA-templated;GO:0006029//proteoglycan metabolic process;GO:0031589//cell-substrate adhesion;GO:0060612//adipose tissue development;GO:0014912//negative regulation of smooth muscle cell migration;GO:0050680//negative regulation of epithelial cell proliferation","K04504//peroxisome proliferator-activated receptor delta","NP_006229.1//peroxisome proliferator-activated receptor delta isoform 1 [Homo sapiens];NP_803184.1//peroxisome proliferator-activated receptor delta isoform 2 [Homo sapiens];NP_001165290.1//peroxisome proliferator-activated receptor delta isoform 3 [Homo sapiens];NP_001165291.1//peroxisome proliferator-activated receptor delta isoform 4 [Homo sapiens]","4;1//3;2//1"]
[5536,2213,73.42,72.23,-0.0235749440583918,0.632805417325456,"*",0.47605,"PPP5C","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:1990635//proximal dendrite;GO:0043234//protein complex;GO:0005829//cytosol;GO:0071944//cell periphery;GO:0005886//plasma membrane;GO:0043204//perikaryon","GO:0003723//RNA binding;GO:0005524//ATP binding;GO:0031072//heat shock protein binding;GO:0042802//identical protein binding;GO:0004722//protein serine/threonine phosphatase activity;GO:0008017//microtubule binding;GO:0043531//ADP binding;GO:0008289//lipid binding;GO:0051879//Hsp90 protein binding;GO:0046872//metal ion binding;GO:0001965//G-protein alpha-subunit binding;GO:0004721//phosphoprotein phosphatase activity;GO:0004871//signal transducer activity","GO:0051291//protein heterooligomerization;GO:1901215//negative regulation of neuron death;GO:0000278//mitotic cell cycle;GO:0000165//MAPK cascade;GO:0006281//DNA repair;GO:0016576//histone dephosphorylation;GO:0043278//response to morphine;GO:0006351//transcription, DNA-templated;GO:2000324//positive regulation of glucocorticoid receptor signaling pathway;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0010288//response to lead ion;GO:0001933//negative regulation of protein phosphorylation;GO:0006470//protein dephosphorylation;GO:0071276//cellular response to cadmium ion;GO:0070301//cellular response to hydrogen peroxide","K04460//serine/threonine-protein phosphatase 5 [EC:3.1.3.16]","NP_006238.1//serine/threonine-protein phosphatase 5 isoform 1 [Homo sapiens];NP_001191213.1//serine/threonine-protein phosphatase 5 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[84968,2278,4.32,4.25,-0.0235684711384045,0.953725742392445,"*",0.91038,"PNMA6A","NA","NA","NA","K06236//collagen, type I, alpha;K19720//collagen, type III, alpha","NP_116271.3//paraneoplastic antigen-like protein 6A [Homo sapiens]",5]
[665,3505,15.43,15.18,-0.0235662711552686,0.862199806486781,"*",0.79214,"BNIP3L","GO:0005740//mitochondrial envelope;GO:0005783//endoplasmic reticulum;GO:0005635//nuclear envelope;GO:0016607//nuclear speck;GO:0005741//mitochondrial outer membrane;GO:0031224//intrinsic component of membrane;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005739//mitochondrion","GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0005521//lamin binding","GO:0071456//cellular response to hypoxia;GO:0043069//negative regulation of programmed cell death;GO:0035694//mitochondrial protein catabolic process;GO:0051607//defense response to virus;GO:1903146//regulation of autophagy of mitochondrion;GO:0043066//negative regulation of apoptotic process;GO:0016032//viral process;GO:0043065//positive regulation of apoptotic process;GO:0016239//positive regulation of macroautophagy;GO:1903214//regulation of protein targeting to mitochondrion;GO:0097345//mitochondrial outer membrane permeabilization;GO:0010917//negative regulation of mitochondrial membrane potential;GO:0060548//negative regulation of cell death;GO:0042981//regulation of apoptotic process;GO:0035794//positive regulation of mitochondrial membrane permeability","K15465//BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like","ERE87539.1//serine/threonine-protein phosphatase 2A regulatory subunit B alpha isoform [Cricetulus griseus];XP_003272940.2//PREDICTED: BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like isoform X1 [Nomascus leucogenys]","1//3;2//1"]
[80775,1484,23.06,22.69,-0.0233359039794343,0.805650390555829,"*",0.717742,"TMEM177","GO:0016021//integral component of membrane","NA","NA","NA","XP_008970744.2//PREDICTED: transmembrane protein 177 isoform X1 [Pan paniscus]","1//3;2//1"]
[162968,3521,2.51,2.47,-0.0231763223660943,0.90972837007348,"*",0.85255,"ZNF497","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_007505752.1//PREDICTED: zinc finger protein 497 [Monodelphis domestica]","1//3;2//1"]
[4598,2068,19.48,19.17,-0.0231433404141915,0.944499169289524,"*",0.897966,"MVK","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0004496//mevalonate kinase activity","GO:0008299//isoprenoid biosynthetic process;GO:0019287//isopentenyl diphosphate biosynthetic process, mevalonate pathway;GO:0006695//cholesterol biosynthetic process;GO:0050728//negative regulation of inflammatory response;GO:0045540//regulation of cholesterol biosynthetic process","K00869//mevalonate kinase [EC:2.7.1.36]","NP_001288111.1//mevalonate kinase isoform b [Homo sapiens];BAD92959.1//mevalonate kinase variant, partial [Homo sapiens]","1//3;3//A2MP1;2//1"]
[84321,1617,63.58,62.57,-0.0231019124386378,0.812180366764582,"*",0.726966,"THOC3","GO:0000784//nuclear chromosome, telomeric region;GO:0005654//nucleoplasm;GO:0000445//THO complex part of transcription export complex;GO:0016607//nuclear speck;GO:0000346//transcription export complex","GO:0003723//RNA binding","GO:0006406//mRNA export from nucleus;GO:0046784//viral mRNA export from host cell nucleus;GO:0006369//termination of RNA polymerase II transcription;GO:0008380//RNA splicing;GO:0031124//mRNA 3'-end processing;GO:0006405//RNA export from nucleus","K12880//THO complex subunit 3","XP_019493024.1//PREDICTED: THO complex subunit 3 [Hipposideros armiger]","3//A2MP1"]
[54802,2146,5.68,5.59,-0.0230426466614919,0.857977458891013,"*",0.786542,"TRIT1","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0005524//ATP binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0052381//tRNA dimethylallyltransferase activity;GO:0003676//nucleic acid binding","GO:0006400//tRNA modification;GO:0070900//mitochondrial tRNA modification;GO:0008033//tRNA processing","K00791//tRNA dimethylallyltransferase [EC:2.5.1.75]","NP_060116.2//tRNA dimethylallyltransferase, mitochondrial isoform 1 precursor [Homo sapiens];NP_001299620.1//tRNA dimethylallyltransferase, mitochondrial isoform 2 [Homo sapiens];NP_001299621.1//tRNA dimethylallyltransferase, mitochondrial isoform 3 [Homo sapiens]","1//3;5"]
[10287,1571,20.28,19.96,-0.0229459316660799,0.92998459162026,"*",0.87817,"RGS19","GO:0016020//membrane;GO:0045121//membrane raft;GO:0005903//brush border;GO:0005794//Golgi apparatus;GO:0031410//cytoplasmic vesicle;GO:0030136//clathrin-coated vesicle","GO:0001965//G-protein alpha-subunit binding;GO:0005096//GTPase activator activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0007264//small GTPase mediated signal transduction;GO:0009968//negative regulation of signal transduction;GO:0006914//autophagy","K16449//regulator of G-protein signaling","NP_005864.1//regulator of G-protein signaling 19 [Homo sapiens];XP_005604926.1//PREDICTED: regulator of G-protein signaling 19 isoform X1 [Equus caballus]","1//3;2//1"]
[51071,1821,19.71,19.4,-0.022871123968996,0.896722175278486,"*",0.836544,"DERA","GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005829//cytosol;GO:1904813//ficolin-1-rich granule lumen;GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0004139//deoxyribose-phosphate aldolase activity","GO:0006098//pentose-phosphate shunt;GO:0043312//neutrophil degranulation;GO:0046386//deoxyribose phosphate catabolic process;GO:0009264//deoxyribonucleotide catabolic process;GO:0046121//deoxyribonucleoside catabolic process;GO:0016052//carbohydrate catabolic process","K01619//deoxyribose-phosphate aldolase [EC:4.1.2.4]","AAH56234.1//DERA protein, partial [Homo sapiens]","1//3;3//A2MP1"]
[54554,4183,2.55,2.51,-0.022809882908086,0.956984395915161,"*",0.915168,"WDR5B","GO:0036064//ciliary basal body","NA","GO:0060271//cilium assembly","K14963//COMPASS component SWD3","XP_021548341.1//WD repeat-containing protein 5B [Neomonachus schauinslandi]","3//A2MP1"]
[55041,4249,31.38,30.89,-0.0227054813404598,0.583504690527035,"*",0.427638,"PLEKHB2","GO:0055038//recycling endosome membrane;GO:0016021//integral component of membrane","GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding","GO:0045595//regulation of cell differentiation","K12581//CCR4-NOT transcription complex subunit 7/8;K07560//D-tyrosyl-tRNA(Tyr) deacylase [EC:3.1.-.-];K16506//protocadherin Fat 1/2/3;K08857//NIMA (never in mitosis gene a)-related kinase 1/4/5 [EC:2.7.11.1];K00968//choline-phosphate cytidylyltransferase [EC:2.7.7.15];K04487//cysteine desulfurase [EC:2.8.1.7]","NP_001094093.1//pleckstrin homology domain-containing family B member 2 isoform 3 [Homo sapiens];NP_060428.2//pleckstrin homology domain-containing family B member 2 isoform 2 [Homo sapiens];XP_016804803.1//PREDICTED: pleckstrin homology domain-containing family B member 2 isoform X3 [Pan troglodytes];XP_016804807.1//PREDICTED: pleckstrin homology domain-containing family B member 2 isoform X7 [Pan troglodytes];NP_001253997.1//pleckstrin homology domain-containing family B member 2 isoform 10 [Homo sapiens];NP_001253995.1//pleckstrin homology domain-containing family B member 2 isoform 8 [Homo sapiens];XP_016804806.1//PREDICTED: pleckstrin homology domain-containing family B member 2 isoform X6 [Pan troglodytes];NP_001296379.1//pleckstrin homology domain-containing family B member 2 isoform 12 [Homo sapiens];NP_001253996.1//pleckstrin homology domain-containing family B member 2 isoform 9 [Homo sapiens];XP_016804808.1//PREDICTED: pleckstrin homology domain-containing family B member 2 isoform X8 [Pan troglodytes];XP_016804805.1//PREDICTED: pleckstrin homology domain-containing family B member 2 isoform X5 [Pan troglodytes];XP_016804804.1//PREDICTED: pleckstrin homology domain-containing family B member 2 isoform X4 [Pan troglodytes]","1//3;2//1"]
[10197,3457,146.2,143.93,-0.0225759802246578,0.617093238087262,"*",0.461294,"PSME3","GO:0016020//membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000502//proteasome complex;GO:0005829//cytosol;GO:0008537//proteasome activator complex;GO:0005737//cytoplasm","GO:0008233//peptidase activity;GO:0061133//endopeptidase activator activity;GO:0002039//p53 binding;GO:0042802//identical protein binding;GO:0097371//MDM2/MDM4 family protein binding","GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:0043687//post-translational protein modification;GO:0038061//NIK/NF-kappaB signaling;GO:0010950//positive regulation of endopeptidase activity;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0006521//regulation of cellular amino acid metabolic process;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0016579//protein deubiquitination;GO:0043488//regulation of mRNA stability;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0000209//protein polyubiquitination;GO:0055085//transmembrane transport;GO:0000165//MAPK cascade;GO:0050852//T cell receptor signaling pathway;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0061136//regulation of proteasomal protein catabolic process;GO:0006915//apoptotic process;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:1902036//regulation of hematopoietic stem cell differentiation;GO:0007049//cell cycle","K06698//proteasome activator subunit 3 (PA28 gamma)","NP_035322.1//proteasome activator complex subunit 3 [Mus musculus];XP_011854159.1//PREDICTED: proteasome activator complex subunit 3 isoform X1 [Mandrillus leucophaeus];NP_789839.1//proteasome activator complex subunit 3 isoform 2 [Homo sapiens];XP_021579933.1//proteasome activator complex subunit 3 isoform X2 [Ictidomys tridecemlineatus]","1//3;3//A2MP1;2//1"]
[200030,5397,2.6,2.56,-0.0223678130284546,0.710440073731343,"*",0.595962,"NBPF11","GO:0005737//cytoplasm","NA","NA","K22244//regenerating islet-derived protein 4;K16549//myomegalin","NP_001265070.1//neuroblastoma breakpoint family member 12 [Homo sapiens]","4;5"]
[2281,868,4.6,4.53,-0.02212281089814,0.7937222918461,"*",0.703836,"FKBP1B","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0030018//Z disc;GO:0005829//cytosol;GO:0034704//calcium channel complex;GO:0033017//sarcoplasmic reticulum membrane;GO:0005737//cytoplasm;GO:0016529//sarcoplasmic reticulum","GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0044325//ion channel binding;GO:0030551//cyclic nucleotide binding;GO:0019855//calcium channel inhibitor activity;GO:0005528//FK506 binding;GO:0005102//receptor binding","GO:0034220//ion transmembrane transport;GO:0032515//negative regulation of phosphoprotein phosphatase activity;GO:0030073//insulin secretion;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0061077//chaperone-mediated protein folding;GO:0033197//response to vitamin E;GO:0009749//response to glucose;GO:0060314//regulation of ryanodine-sensitive calcium-release channel activity;GO:0061179//negative regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0006458//'de novo' protein folding;GO:0019227//neuronal action potential propagation;GO:0051775//response to redox state;GO:0051209//release of sequestered calcium ion into cytosol;GO:0060315//negative regulation of ryanodine-sensitive calcium-release channel activity;GO:0014808//release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0051284//positive regulation of sequestering of calcium ion;GO:0035584//calcium-mediated signaling using intracellular calcium source;GO:0022417//protein maturation by protein folding;GO:0010459//negative regulation of heart rate;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0010033//response to organic substance;GO:0086064//cell communication by electrical coupling involved in cardiac conduction;GO:0000413//protein peptidyl-prolyl isomerization;GO:0010881//regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion;GO:1903779//regulation of cardiac conduction;GO:0006939//smooth muscle contraction;GO:0048680//positive regulation of axon regeneration;GO:0042542//response to hydrogen peroxide;GO:0002027//regulation of heart rate;GO:0051280//negative regulation of release of sequestered calcium ion into cytosol;GO:0042098//T cell proliferation;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0042026//protein refolding","K09568//FK506-binding protein 1 [EC:5.2.1.8]","XP_004582689.1//PREDICTED: peptidyl-prolyl cis-trans isomerase FKBP1B isoform X1 [Ochotona princeps];XP_011806202.1//PREDICTED: peptidyl-prolyl cis-trans isomerase FKBP1B isoform X2 [Colobus angolensis palliatus];NP_004107.1//peptidyl-prolyl cis-trans isomerase FKBP1B isoform a [Homo sapiens]","4;1//3;3//A2MP1"]
[375061,1516,14.47,14.25,-0.0221030025922583,0.932116811816917,"*",0.880942,"FAM89A","NA","NA","NA","K19941//synapsin;K16608//tubulin monoglycylase TTLL3/8 [EC:6.3.2.-]","NP_940954.1//protein FAM89A [Homo sapiens]","2//1"]
[84623,3758,3.29,3.24,-0.0220937708506167,0.963461354063235,"*",0.923292,"KIRREL3","GO:0043198//dendritic shaft;GO:0030425//dendrite;GO:0030424//axon;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane","NA","GO:0021740//principal sensory nucleus of trigeminal nerve development;GO:0021766//hippocampus development;GO:0007416//synapse assembly;GO:0072102//glomerulus morphogenesis;GO:0002121//inter-male aggressive behavior;GO:0001764//neuron migration;GO:0048812//neuron projection morphogenesis;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0030097//hemopoiesis","K16680//echinoid;K18273//alpha-tectorin","NP_001155179.1//kin of IRRE-like protein 3 isoform 2 precursor [Homo sapiens];NP_115920.1//kin of IRRE-like protein 3 isoform 1 precursor [Homo sapiens];NP_001288026.1//kin of IRRE-like protein 3 isoform 3 precursor [Homo sapiens]","1//3;3//A2MP1"]
[2588,2304,28.37,27.94,-0.0220341298648957,0.926169657085961,"*",0.873466,"GALNS","GO:0070062//extracellular exosome;GO:0035578//azurophil granule lumen;GO:0043202//lysosomal lumen;GO:0005576//extracellular region","GO:0046872//metal ion binding;GO:0008484//sulfuric ester hydrolase activity;GO:0043890//N-acetylgalactosamine-6-sulfatase activity;GO:0003943//N-acetylgalactosamine-4-sulfatase activity","GO:0008152//metabolic process;GO:0042340//keratan sulfate catabolic process;GO:0043312//neutrophil degranulation","K01132//N-acetylgalactosamine-6-sulfatase [EC:3.1.6.4]","NP_001310473.1//N-acetylgalactosamine-6-sulfatase isoform 2 [Homo sapiens];XP_007992549.1//PREDICTED: LOW QUALITY PROTEIN: N-acetylgalactosamine-6-sulfatase [Chlorocebus sabaeus]","1//3;4"]
[7385,2226,77.24,76.07,-0.0220205592393431,0.767650974660828,"*",0.669472,"UQCRC2","GO:0070062//extracellular exosome;GO:0005654//nucleoplasm;GO:0043209//myelin sheath;GO:0005750//mitochondrial respiratory chain complex III;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0005751//mitochondrial respiratory chain complex IV","GO:0046872//metal ion binding;GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding;GO:0032403//protein complex binding","GO:0006627//protein processing involved in protein targeting to mitochondrion;GO:0006119//oxidative phosphorylation;GO:0009060//aerobic respiration;GO:0006122//mitochondrial electron transport, ubiquinol to cytochrome c","K00415//ubiquinol-cytochrome c reductase core subunit 2","NP_003357.2//cytochrome b-c1 complex subunit 2, mitochondrial precursor [Homo sapiens]","3//A2MP1"]
[84759,939,23.14,22.79,-0.0219879398421928,0.93021023223754,"*",0.878616,"PCGF1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031519//PcG protein complex","GO:0046872//metal ion binding;GO:0008022//protein C-terminus binding","GO:0035518//histone H2A monoubiquitination;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0036353//histone H2A-K119 monoubiquitination","K11487//polycomb group RING finger protein 1","NP_116062.2//polycomb group RING finger protein 1 [Homo sapiens]","2//1"]
[50515,5759,7.28,7.17,-0.0219653314967916,0.891461128639634,"*",0.829906,"CHST11","GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0001537//N-acetylgalactosamine 4-O-sulfotransferase activity;GO:0047756//chondroitin 4-sulfotransferase activity;GO:0008146//sulfotransferase activity;GO:0050659//N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity","GO:0007585//respiratory gaseous exchange;GO:0016051//carbohydrate biosynthetic process;GO:0042127//regulation of cell proliferation;GO:0048703//embryonic viscerocranium morphogenesis;GO:0030206//chondroitin sulfate biosynthetic process;GO:0002063//chondrocyte development;GO:0043066//negative regulation of apoptotic process;GO:0036342//post-anal tail morphogenesis;GO:0042733//embryonic digit morphogenesis;GO:0009791//post-embryonic development;GO:0033037//polysaccharide localization;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0048589//developmental growth","K01017//chondroitin 4-sulfotransferase 11 [EC:2.8.2.5]","NP_060883.1//carbohydrate sulfotransferase 11 isoform 1 [Homo sapiens];NP_001167453.1//carbohydrate sulfotransferase 11 isoform 2 [Homo sapiens]","1//3;5"]
[1018,1584,6.63,6.53,-0.0219258785661569,0.955732329578203,"*",0.913492,"CDK3","GO:0005634//nucleus;GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0005737//cytoplasm","GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0030332//cyclin binding","GO:0010468//regulation of gene expression;GO:0007165//signal transduction;GO:0006468//protein phosphorylation;GO:0010389//regulation of G2/M transition of mitotic cell cycle;GO:0008283//cell proliferation;GO:0045023//G0 to G1 transition;GO:0010033//response to organic substance;GO:0051301//cell division;GO:0007275//multicellular organism development;GO:0000082//G1/S transition of mitotic cell cycle;GO:0006974//cellular response to DNA damage stimulus;GO:0008284//positive regulation of cell proliferation","K02088//cyclin-dependent kinase 3 [EC:2.7.11.22]","XP_008964060.1//PREDICTED: cyclin-dependent kinase 3 isoform X1 [Pan paniscus]","2//1"]
[8220,5405,4.01,3.95,-0.021749583390455,0.932830821721854,"*",0.881792,"ESS2","GO:0005634//nucleus;GO:0071013//catalytic step 2 spliceosome","NA","GO:0007399//nervous system development;GO:0000398//mRNA splicing, via spliceosome","K13118//protein DGCR14","XP_017712197.1//PREDICTED: protein DGCR14 [Rhinopithecus bieti]","2//1"]
[2806,2441,130.84,128.91,-0.0214394815876836,0.590906050923955,"*",0.434394,"GOT2","GO:0005759//mitochondrial matrix;GO:0070062//extracellular exosome;GO:0009986//cell surface;GO:0043234//protein complex;GO:0043209//myelin sheath;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0043204//perikaryon","GO:0047578//4-hydroxyglutamate transaminase activity;GO:0003723//RNA binding;GO:0016597//amino acid binding;GO:0004069//L-aspartate:2-oxoglutarate aminotransferase activity;GO:0016212//kynurenine-oxoglutarate transaminase activity;GO:0042803//protein homodimerization activity;GO:0005543//phospholipid binding;GO:0080130//L-phenylalanine:2-oxoglutarate aminotransferase activity;GO:0030170//pyridoxal phosphate binding;GO:0019899//enzyme binding","GO:0019550//glutamate catabolic process to aspartate;GO:0008652//cellular amino acid biosynthetic process;GO:0015908//fatty acid transport;GO:0006531//aspartate metabolic process;GO:0006532//aspartate biosynthetic process;GO:0006094//gluconeogenesis;GO:0019470//4-hydroxyproline catabolic process;GO:0019551//glutamate catabolic process to 2-oxoglutarate;GO:0045471//response to ethanol;GO:0006533//aspartate catabolic process;GO:0006536//glutamate metabolic process;GO:0006107//oxaloacetate metabolic process;GO:0006103//2-oxoglutarate metabolic process;GO:0046487//glyoxylate metabolic process","K14455//aspartate aminotransferase, mitochondrial [EC:2.6.1.1]","NP_001273149.1//aspartate aminotransferase, mitochondrial isoform 2 precursor [Homo sapiens];NP_002071.2//aspartate aminotransferase, mitochondrial isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[5581,5537,2.04,2.01,-0.0213736507925672,0.960110032842656,"*",0.918698,"PRKCE","GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0071944//cell periphery;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0005739//mitochondrion;GO:0005886//plasma membrane","GO:0030546//receptor activator activity;GO:0005524//ATP binding;GO:0004697//protein kinase C activity;GO:0003785//actin monomer binding;GO:0035276//ethanol binding;GO:0071889//14-3-3 protein binding;GO:0046872//metal ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0004699//calcium-independent protein kinase C activity;GO:0004871//signal transducer activity;GO:0008047//enzyme activator activity;GO:0019899//enzyme binding","GO:0010763//positive regulation of fibroblast migration;GO:2001031//positive regulation of cellular glucuronidation;GO:0050730//regulation of peptidyl-tyrosine phosphorylation;GO:0035669//TRAM-dependent toll-like receptor 4 signaling pathway;GO:1903078//positive regulation of protein localization to plasma membrane;GO:2000650//negative regulation of sodium ion transmembrane transporter activity;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0032467//positive regulation of cytokinesis;GO:0071361//cellular response to ethanol;GO:0007165//signal transduction;GO:0006468//protein phosphorylation;GO:0035641//locomotory exploration behavior;GO:0050996//positive regulation of lipid catabolic process;GO:0006915//apoptotic process;GO:0090303//positive regulation of wound healing;GO:0007155//cell adhesion;GO:0032230//positive regulation of synaptic transmission, GABAergic;GO:0018105//peptidyl-serine phosphorylation;GO:0071380//cellular response to prostaglandin E stimulus;GO:0007202//activation of phospholipase C activity;GO:0051209//release of sequestered calcium ion into cytosol;GO:0071456//cellular response to hypoxia;GO:0031397//negative regulation of protein ubiquitination;GO:0032024//positive regulation of insulin secretion;GO:0070257//positive regulation of mucus secretion;GO:0043278//response to morphine;GO:0051279//regulation of release of sequestered calcium ion into cytosol;GO:0035556//intracellular signal transduction;GO:0030168//platelet activation;GO:0010634//positive regulation of epithelial cell migration;GO:0061178//regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0002281//macrophage activation involved in immune response;GO:0030838//positive regulation of actin filament polymerization;GO:0010811//positive regulation of cell-substrate adhesion;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0051301//cell division;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0043410//positive regulation of MAPK cascade;GO:0007049//cell cycle","K18050//novel protein kinase C epsilon type [EC:2.7.11.13]","NP_005391.1//protein kinase C epsilon type [Homo sapiens]","2//1"]
[55884,2819,37.12,36.58,-0.0211416353788556,0.543724799300699,"*",0.389396,"WSB2","GO:0005829//cytosol;GO:0005622//intracellular","NA","GO:0043687//post-translational protein modification;GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction","K10342//WD repeat and SOCS box-containing protein 2","XP_012805499.1//PREDICTED: WD repeat and SOCS box-containing protein 2 isoform X2 [Jaculus jaculus];NP_001265486.1//WD repeat and SOCS box-containing protein 2 isoform 1 [Homo sapiens];XP_021531172.1//WD repeat and SOCS box-containing protein 2 [Aotus nancymaae]","1//3;4"]
[8559,1711,6.88,6.78,-0.0211232915657539,0.960892877640442,"*",0.919808,"PRPF18","GO:0005634//nucleus;GO:0071021//U2-type post-spliceosomal complex;GO:0005681//spliceosomal complex;GO:0005682//U5 snRNP;GO:0016607//nuclear speck;GO:0046540//U4/U6 x U5 tri-snRNP complex","NA","GO:0071048//nuclear retention of unspliced pre-mRNA at the site of transcription;GO:0006397//mRNA processing;GO:0000350//generation of catalytic spliceosome for second transesterification step;GO:0008380//RNA splicing","K12817//pre-mRNA-splicing factor 18","XP_002717659.3//PREDICTED: pre-mRNA-splicing factor 18 [Oryctolagus cuniculus]","3//A2MP1"]
[84320,1617,27.52,27.12,-0.0211232915657539,0.89503772035208,"*",0.833908,"ACBD6","GO:0005829//cytosol","GO:0008289//lipid binding;GO:0000062//fatty-acyl-CoA binding","GO:0006637//acyl-CoA metabolic process","K10799//tankyrase [EC:2.4.2.30]","NP_115736.1//acyl-CoA-binding domain-containing protein 6 [Homo sapiens]","3//A2MP1"]
[152137,8604,3.46,3.41,-0.021000298612552,0.926854587641866,"*",0.874228,"CCDC50","GO:0005829//cytosol","GO:0031625//ubiquitin protein ligase binding","GO:0007605//sensory perception of sound","K12581//CCR4-NOT transcription complex subunit 7/8;K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K17985//activating molecule in BECN1-regulated autophagy protein 1;K01064//wingless-type MMTV integration site family, member 9","XP_011379793.1//PREDICTED: coiled-coil domain-containing protein 50 [Pteropus vampyrus];NP_848018.1//coiled-coil domain-containing protein 50 long isoform [Homo sapiens]","3//A2MP1;2//1"]
[57109,2349,19.45,19.17,-0.0209198182054035,0.536755007637609,"*",0.382758,"REXO4","GO:0005634//nucleus;GO:0005730//nucleolus;GO:0016607//nuclear speck","GO:0003723//RNA binding;GO:0004527//exonuclease activity;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated","K18327//RNA exonuclease 4 [EC:3.1.-.-]","NP_001266278.1//RNA exonuclease 4 isoform 2 [Homo sapiens];NP_065118.2//RNA exonuclease 4 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[9861,1395,37.09,36.56,-0.02076419744494,0.45156685410844,"*",0.303438,"PSMD6","GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome;GO:0005654//nucleoplasm;GO:0000502//proteasome complex;GO:0022624//proteasome accessory complex;GO:0005838//proteasome regulatory particle;GO:0005829//cytosol;GO:0005576//extracellular region;GO:1904813//ficolin-1-rich granule lumen","GO:0030234//enzyme regulator activity;GO:0016887//ATPase activity","GO:0043687//post-translational protein modification;GO:0038061//NIK/NF-kappaB signaling;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0006521//regulation of cellular amino acid metabolic process;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0016579//protein deubiquitination;GO:0043312//neutrophil degranulation;GO:0043488//regulation of mRNA stability;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0000209//protein polyubiquitination;GO:0055085//transmembrane transport;GO:0000165//MAPK cascade;GO:0050852//T cell receptor signaling pathway;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0006508//proteolysis;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:1902036//regulation of hematopoietic stem cell differentiation","K03037//26S proteasome regulatory subunit N7","NP_001258709.1//26S proteasome non-ATPase regulatory subunit 6 isoform 3 [Homo sapiens];XP_017382846.1//PREDICTED: 26S proteasome non-ATPase regulatory subunit 6 [Cebus capucinus imitator];NP_001258710.1//26S proteasome non-ATPase regulatory subunit 6 isoform 4 [Homo sapiens];NP_001258708.1//26S proteasome non-ATPase regulatory subunit 6 isoform 1 [Homo sapiens]","1//3;2//1"]
[1949,3236,1.4,1.38,-0.0207585601667975,0.971878312263782,"*",0.93367,"EFNB3","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0046875//ephrin receptor binding;GO:0016301//kinase activity;GO:0001618//virus receptor activity;GO:0005005//transmembrane-ephrin receptor activity","GO:0007399//nervous system development;GO:0016198//axon choice point recognition;GO:0048013//ephrin receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0031295//T cell costimulation;GO:0007628//adult walking behavior;GO:0050771//negative regulation of axonogenesis;GO:0007411//axon guidance","K05463//ephrin-B","NP_001397.1//ephrin-B3 precursor [Homo sapiens]","3//A2MP1"]
[57226,5371,5.63,5.55,-0.0206471508427613,0.929159453544665,"*",0.8771,"LYRM2","GO:0005739//mitochondrion","NA","NA","K12824//transcription elongation regulator 1","XP_004310756.2//PREDICTED: LYR motif-containing protein 2 [Tursiops truncatus]",4]
[53947,2156,7.84,7.73,-0.0203852401903607,0.945131135789474,"*",0.899336,"A4GALT","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0030173//integral component of Golgi membrane;GO:0016021//integral component of membrane","GO:0016757//transferase activity, transferring glycosyl groups;GO:0015643//toxic substance binding;GO:0050512//lactosylceramide 4-alpha-galactosyltransferase activity;GO:0008378//galactosyltransferase activity","GO:0006486//protein glycosylation;GO:0006688//glycosphingolipid biosynthetic process;GO:0001576//globoside biosynthetic process;GO:0007009//plasma membrane organization","K01988//lactosylceramide 4-alpha-galactosyltransferase [EC:2.4.1.228]","NP_059132.1//lactosylceramide 4-alpha-galactosyltransferase [Homo sapiens]","6;2//1"]
[5018,1737,151.91,149.79,-0.0202755308440995,0.734171366336634,"*",0.631312,"OXA1L","GO:0043234//protein complex;GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0031966//mitochondrial membrane;GO:0005746//mitochondrial respiratory chain;GO:0032592//integral component of mitochondrial membrane","GO:0097177//mitochondrial ribosome binding;GO:0042803//protein homodimerization activity","GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0032780//negative regulation of ATPase activity;GO:0097031//mitochondrial respiratory chain complex I biogenesis;GO:0051262//protein tetramerization;GO:0051354//negative regulation of oxidoreductase activity;GO:0055114//oxidation-reduction process;GO:0009060//aerobic respiration;GO:0033615//mitochondrial proton-transporting ATP synthase complex assembly;GO:0051205//protein insertion into membrane;GO:0006461//protein complex assembly","K03217//YidC/Oxa1 family membrane protein insertase","NP_005006.3//mitochondrial inner membrane protein OXA1L [Homo sapiens]","3//A2MP1"]
[5954,2529,78.48,77.39,-0.0201778819376304,0.775383315947843,"*",0.677526,"RCN1","GO:0005783//endoplasmic reticulum","GO:0005509//calcium ion binding","GO:0043010//camera-type eye development;GO:0001701//in utero embryonic development","K19934//calcium-binding protein;K12804//proline-serine-threonine phosphatase interacting protein 1;K17286//erythrocyte band 7 integral membrane protein","XP_003353965.2//reticulocalbin-1 [Sus scrofa]","2//1"]
[8314,3717,18.83,18.57,-0.0200591846788074,0.873211372235039,"*",0.805646,"BAP1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0035517//PR-DUB complex;GO:0005737//cytoplasm","GO:0004843//thiol-dependent ubiquitin-specific protease activity;GO:0008233//peptidase activity;GO:0003682//chromatin binding;GO:0036459//thiol-dependent ubiquitinyl hydrolase activity","GO:0001558//regulation of cell growth;GO:0071108//protein K48-linked deubiquitination;GO:1900015//regulation of cytokine production involved in inflammatory response;GO:1903955//positive regulation of protein targeting to mitochondrion;GO:0035522//monoubiquitinated histone H2A deubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006464//cellular protein modification process;GO:0010035//response to inorganic substance;GO:0061519//macrophage homeostasis;GO:0035520//monoubiquitinated protein deubiquitination;GO:0016579//protein deubiquitination;GO:0051726//regulation of cell cycle;GO:0008285//negative regulation of cell proliferation","K08588//ubiquitin carboxyl-terminal hydrolase BAP1 [EC:3.4.19.12]","NP_004647.1//ubiquitin carboxyl-terminal hydrolase BAP1 [Homo sapiens]","3//A2MP1"]
[112937,2959,0.73,0.72,-0.0198995574377049,0.944215408100099,"*",0.897578,"GLB1L3","GO:0005773//vacuole","GO:0004565//beta-galactosidase activity","GO:0005975//carbohydrate metabolic process","K12309//beta-galactosidase [EC:3.2.1.23]","NP_001073876.2//beta-galactosidase-1-like protein 3 [Homo sapiens]","2//1"]
[90141,2626,6.58,6.49,-0.0198691057361029,0.831215542406857,"*",0.752798,"EFCAB11","NA","GO:0005509//calcium ion binding","NA","K16465//centrin-1;K07560//D-tyrosyl-tRNA(Tyr) deacylase [EC:3.1.-.-];K17985//activating molecule in BECN1-regulated autophagy protein 1;K02183//calmodulin;K12755//myosin regulatory light chain 9","NP_660274.1//EF-hand calcium-binding domain-containing protein 11 isoform 1 [Homo sapiens];NP_001271195.1//EF-hand calcium-binding domain-containing protein 11 isoform 2 [Homo sapiens];NP_001271198.1//EF-hand calcium-binding domain-containing protein 11 isoform 5 [Homo sapiens];NP_001271197.1//EF-hand calcium-binding domain-containing protein 11 isoform 4 [Homo sapiens]","1//3;3//A2MP1"]
[54552,8592,13.9,13.71,-0.0198563118316438,0.813171655408713,"*",0.728006,"GNL3L","GO:0016020//membrane;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005697//telomerase holoenzyme complex","GO:0003723//RNA binding;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0031397//negative regulation of protein ubiquitination;GO:0042254//ribosome biogenesis;GO:0090073//positive regulation of protein homodimerization activity;GO:0031647//regulation of protein stability;GO:0032091//negative regulation of protein binding;GO:1904816//positive regulation of protein localization to chromosome, telomeric region;GO:0032211//negative regulation of telomere maintenance via telomerase;GO:0033234//negative regulation of protein sumoylation","K14538//nuclear GTP-binding protein","NP_061940.1//guanine nucleotide-binding protein-like 3-like protein [Homo sapiens]","1//3;5"]
[339366,2867,3.66,3.61,-0.0198448113968717,0.956115405855,"*",0.913918,"ADAMTSL5","GO:0001527//microfibril;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix","GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding;GO:0008201//heparin binding","NA","K15686//RNA-binding protein MEX3 [EC:2.3.2.27];K08621//a disintegrin and metalloproteinase with thrombospondin motifs 6 [EC:3.4.24.-]","NP_998769.2//ADAMTS-like protein 5 precursor [Homo sapiens]","2//1"]
[10799,1105,16.89,16.66,-0.0197809274358381,0.920837862940785,"*",0.86642,"RPP40","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005655//nucleolar ribonuclease P complex","GO:0004526//ribonuclease P activity","GO:0001682//tRNA 5'-leader removal;GO:0006364//rRNA processing","K14530//ribonucleases P/MRP protein subunit RPP40 [EC:3.1.26.5]","NP_001273061.1//ribonuclease P protein subunit p40 isoform b [Homo sapiens];NP_001273062.1//ribonuclease P protein subunit p40 isoform c [Homo sapiens];NP_006629.2//ribonuclease P protein subunit p40 isoform a [Homo sapiens]","1//3;3//A2MP1"]
[29896,1931,31.59,31.16,-0.0197727036852038,0.628552320795773,"*",0.506336,"TRA2A","GO:0005730//nucleolus","GO:0003723//RNA binding","GO:0000398//mRNA splicing, via spliceosome","K12897//transformer-2 protein","XP_012369101.1//PREDICTED: transformer-2 protein homolog alpha [Octodon degus];XP_010639422.1//PREDICTED: transformer-2 protein homolog alpha isoform X1 [Fukomys damarensis];XP_008564754.1//PREDICTED: transformer-2 protein homolog alpha isoform X2 [Galeopterus variegatus]","4;1//3"]
[55217,2470,4.41,4.35,-0.0197632548214301,0.974982754670312,"*",0.93769,"TMLHE","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0050353//trimethyllysine dioxygenase activity;GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0005506//iron ion binding","GO:0045329//carnitine biosynthetic process;GO:0051354//negative regulation of oxidoreductase activity","K00474//trimethyllysine dioxygenase [EC:1.14.11.8]","NP_060666.1//trimethyllysine dioxygenase, mitochondrial isoform 1 precursor [Homo sapiens];NP_001171726.1//trimethyllysine dioxygenase, mitochondrial isoform 2 precursor [Homo sapiens]","1//3;3//A2MP1"]
[80039,2281,1.48,1.46,-0.0196288067489325,0.96118275689813,"*",0.920266,"FAM106A","NA","NA","NA","K02927//large subunit ribosomal protein L40e;K15696//RING finger protein 113B;K17985//activating molecule in BECN1-regulated autophagy protein 1","NP_079250.1//protein FAM106A [Homo sapiens]","2//1"]
[284613,4850,4.46,4.4,-0.019540186395645,0.956159793085385,"*",0.91414,"CYB561D1","GO:0016021//integral component of membrane","GO:0046872//metal ion binding","GO:0055114//oxidation-reduction process","K11318//ataxin-7;K08371//cytochrome b-561 domain containing protein 2","XP_017714281.1//PREDICTED: cytochrome b561 domain-containing protein 1 isoform X1 [Rhinopithecus bieti];XP_011539589.2//PREDICTED: cytochrome b561 domain-containing protein 1 isoform X1 [Homo sapiens];XP_017830488.1//PREDICTED: LOW QUALITY PROTEIN: cytochrome b561 domain-containing protein 1 [Callithrix jacchus];EAW56387.1//hCG2043250, isoform CRA_b [Homo sapiens];NP_001127874.1//cytochrome b561 domain-containing protein 1 isoform 3 [Homo sapiens]","1//3;2//1"]
[55374,1866,9.7,9.57,-0.0194658225884644,0.755454666955392,"*",0.655194,"TMCO6","GO:0005634//nucleus;GO:0016021//integral component of membrane;GO:0005737//cytoplasm","GO:0008565//protein transporter activity","GO:0006606//protein import into nucleus","K15043//importin subunit alpha-2","NP_060972.3//transmembrane and coiled-coil domain-containing protein 6 isoform 2 [Homo sapiens];NP_001287909.1//transmembrane and coiled-coil domain-containing protein 6 isoform 1 [Homo sapiens];XP_004042703.2//PREDICTED: transmembrane and coiled-coil domain-containing protein 6 isoform X3 [Gorilla gorilla gorilla]","4;1//3"]
[122616,1908,5.98,5.9,-0.0194305299489014,0.959779876210416,"*",0.918322,"CLBA1","NA","NA","NA","NA","NP_777551.2//uncharacterized protein C14orf79 [Homo sapiens]","3//A2MP1"]
[9946,1726,3.74,3.69,-0.0194174538272407,0.982007380559704,"*",0.946782,"CRYZL1","NA","NA","NA","K10133//tumor protein p53-inducible protein 3 [EC:1.-.-.-]","XP_012602486.1//quinone oxidoreductase-like protein 1 isoform X1 [Microcebus murinus]","2//1"]
[8536,1500,12.74,12.57,-0.0193806278357926,0.951119195323788,"*",0.906582,"CAMK1","NA","NA","NA","K08794//calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]","XP_017820551.1//PREDICTED: LOW QUALITY PROTEIN: calcium/calmodulin-dependent protein kinase type 1 [Callithrix jacchus]",4]
[8602,3672,23.24,22.93,-0.0193737138237354,0.851788612817181,"*",0.779642,"NOP14","GO:0016020//membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0030686//90S preribosome;GO:0030692//Noc4p-Nop14p complex;GO:0005730//nucleolus;GO:0032040//small-subunit processome;GO:0005739//mitochondrion","GO:0030515//snoRNA binding;GO:0003723//RNA binding;GO:0019899//enzyme binding","GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000472//endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0042274//ribosomal small subunit biogenesis;GO:0000447//endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006364//rRNA processing;GO:0030490//maturation of SSU-rRNA;GO:0000480//endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)","K14766//nucleolar protein 14","NP_001278908.1//nucleolar protein 14 isoform 2 [Homo sapiens];AAB97011.1//unknown protein IT12, partial [Homo sapiens]","1//3;2//1"]
[5298,4035,16.5,16.28,-0.0193653248669311,0.212164150167805,"*",0.1147684,"PI4KB","GO:0016020//membrane;GO:0005768//endosome;GO:0030867//rough endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005741//mitochondrial outer membrane;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0000139//Golgi membrane","GO:0071889//14-3-3 protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0004430//1-phosphatidylinositol 4-kinase activity","GO:0007165//signal transduction;GO:0006898//receptor-mediated endocytosis;GO:0048015//phosphatidylinositol-mediated signaling;GO:0006661//phosphatidylinositol biosynthetic process;GO:0046854//phosphatidylinositol phosphorylation","K19801//phosphatidylinositol 4-kinase B [EC:2.7.1.67]","NP_002642.1//phosphatidylinositol 4-kinase beta isoform 1 [Homo sapiens];EDL38764.1//phosphatidylinositol 4-kinase, catalytic, beta polypeptide, isoform CRA_c, partial [Mus musculus];ERE90758.1//phosphatidylinositol 4-kinase beta isoform 2 [Cricetulus griseus];XP_005245321.1//PREDICTED: phosphatidylinositol 4-kinase beta isoform X6 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[51074,1285,19.52,19.26,-0.0193453497194269,0.939342922152526,"*",0.890594,"APIP","GO:0005737//cytoplasm","GO:0042802//identical protein binding;GO:0008270//zinc ion binding;GO:0046570//methylthioribulose 1-phosphate dehydratase activity","GO:0070269//pyroptosis;GO:0051289//protein homotetramerization;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0019284//L-methionine salvage from S-adenosylmethionine;GO:0043066//negative regulation of apoptotic process;GO:0019509//L-methionine salvage from methylthioadenosine;GO:0006915//apoptotic process","K08964//methylthioribulose-1-phosphate dehydratase [EC:4.2.1.109]","NP_057041.2//methylthioribulose-1-phosphate dehydratase [Homo sapiens]","3//A2MP1"]
[5440,971,58.44,57.67,-0.019135155746378,0.896034492045378,"*",0.835622,"POLR2K","NA","NA","NA","K03009//DNA-directed RNA polymerases I, II, and III subunit RPABC4","XP_004011861.2//PREDICTED: DNA-directed RNA polymerases I, II, and III subunit RPABC4 [Ovis aries]","3//A2MP1"]
[26010,6206,17.58,17.35,-0.0189994076777805,0.833710841828982,"*",0.755632,"SPATS2L","GO:0005634//nucleus;GO:0005730//nucleolus;GO:0043234//protein complex;GO:0005829//cytosol","GO:0003723//RNA binding","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K03211//ETS translocation variant 6/7;K04487//cysteine desulfurase [EC:2.8.1.7]","XP_016859273.1//PREDICTED: SPATS2-like protein isoform X3 [Homo sapiens];XP_011829931.1//PREDICTED: SPATS2-like protein isoform X2 [Mandrillus leucophaeus];NP_001269673.1//SPATS2-like protein isoform d [Homo sapiens]","1//3;2//1"]
[3783,2240,13.8,13.62,-0.0189415636534605,0.929883377005702,"*",0.877958,"KCNN4","GO:0031982//vesicle;GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0043025//neuronal cell body","GO:0015269//calcium-activated potassium channel activity;GO:0005267//potassium channel activity;GO:0019903//protein phosphatase binding;GO:0005516//calmodulin binding;GO:0016286//small conductance calcium-activated potassium channel activity","GO:0006813//potassium ion transport;GO:0006884//cell volume homeostasis;GO:0046541//saliva secretion;GO:0030322//stabilization of membrane potential;GO:0006816//calcium ion transport;GO:0050714//positive regulation of protein secretion;GO:0002376//immune system process;GO:0045332//phospholipid translocation;GO:0006952//defense response;GO:0050862//positive regulation of T cell receptor signaling pathway","K04945//potassium intermediate/small conductance calcium-activated channel subfamily N member 4","XP_012302172.1//intermediate conductance calcium-activated potassium channel protein 4 isoform X1 [Aotus nancymaae]","2//1"]
[54472,3633,19.17,18.92,-0.0189382483287554,0.90184584986272,"*",0.843074,"TOLLIP","GO:0070062//extracellular exosome;GO:0035580//specific granule lumen;GO:0045092//interleukin-18 receptor complex;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0035578//azurophil granule lumen;GO:0005829//cytosol;GO:0045323//interleukin-1 receptor complex;GO:0016604//nuclear body;GO:0005576//extracellular region","GO:0031625//ubiquitin protein ligase binding;GO:0031624//ubiquitin conjugating enzyme binding;GO:0035325//Toll-like receptor binding;GO:0005150//interleukin-1, Type I receptor binding;GO:0043130//ubiquitin binding;GO:0019900//kinase binding;GO:0004871//signal transducer activity;GO:0032183//SUMO binding","GO:0036010//protein localization to endosome;GO:0016310//phosphorylation;GO:0007165//signal transduction;GO:0045321//leukocyte activation;GO:0007267//cell-cell signaling;GO:0035556//intracellular signal transduction;GO:0033235//positive regulation of protein sumoylation;GO:0006954//inflammatory response;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006914//autophagy;GO:0043312//neutrophil degranulation;GO:0045087//innate immune response;GO:0030855//epithelial cell differentiation","K05402//toll-interacting protein","NP_001305441.1//toll-interacting protein isoform 2 [Homo sapiens];NP_061882.2//toll-interacting protein isoform 1 [Homo sapiens];NP_001305445.1//toll-interacting protein isoform 4 [Homo sapiens];BAD92778.1//toll interacting protein variant, partial [Homo sapiens]","1//3;3//A2MP1"]
[285381,4046,5.39,5.32,-0.0188590272513157,0.932769048937157,"*",0.881792,"DPH3","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0046872//metal ion binding","GO:0017183//peptidyl-diphthamide biosynthetic process from peptidyl-histidine;GO:0050709//negative regulation of protein secretion;GO:0051099//positive regulation of binding","K15455//diphthamide biosynthesis protein 3","XP_011929659.1//PREDICTED: LOW QUALITY PROTEIN: putative DPH3 homolog B, partial [Cercocebus atys]","2//1"]
[27090,1710,24.67,24.35,-0.0188359433304186,0.909793606358111,"*",0.852782,"ST6GALNAC4","GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0047290//(alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity;GO:0008373//sialyltransferase activity;GO:0001665//alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity","GO:0006664//glycolipid metabolic process;GO:0006486//protein glycosylation;GO:0018279//protein N-linked glycosylation via asparagine;GO:0009311//oligosaccharide metabolic process;GO:0016266//O-glycan processing","K03374//N-acetylgalactosaminide alpha-2,6-sialyltransferase (sialyltransferase 7D) [EC:2.4.99.7]","XP_011516829.1//PREDICTED: alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase isoform X1 [Homo sapiens];NP_778204.1//alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase isoform a [Homo sapiens]","3//A2MP1"]
[58496,774,17.07,16.85,-0.0187144669585172,0.96402411809275,"*",0.923952,"LY6G5B","GO:0043234//protein complex;GO:0005576//extracellular region","GO:0042802//identical protein binding","GO:0051260//protein homooligomerization","K20005//lymphocyte antigen 6 complex locus protein G5","NP_067044.2//lymphocyte antigen 6 complex locus protein G5b precursor [Homo sapiens]","2//1"]
[10432,5415,49.78,49.14,-0.018668372618871,0.758125625270446,"*",0.65808,"RBM14","GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005667//transcription factor complex;GO:0016592//mediator complex;GO:0030529//intracellular ribonucleoprotein complex;GO:0016607//nuclear speck;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0030674//protein binding, bridging;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity","GO:0030520//intracellular estrogen receptor signaling pathway;GO:0006281//DNA repair;GO:0006260//DNA replication;GO:0002218//activation of innate immune response;GO:0006351//transcription, DNA-templated;GO:0042921//glucocorticoid receptor signaling pathway;GO:0060395//SMAD protein signal transduction;GO:0098534//centriole assembly;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0009725//response to hormone;GO:0046600//negative regulation of centriole replication;GO:0006310//DNA recombination;GO:0016575//histone deacetylation;GO:0045087//innate immune response","K13187//RNA-binding protein 4;K13189//RNA-binding protein 14","NP_001185766.1//RNA-binding protein 14 isoform 3 [Homo sapiens];NP_001185765.1//RNA-binding protein 14 isoform 2 [Homo sapiens];NP_006319.1//RNA-binding protein 14 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[100129924,3354,3.12,3.08,-0.0186156781673471,0.997020630855958,"*",0.963254,"TMEM269","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein;K10858//DNA mismatch repair protein PMS2;K01064//wingless-type MMTV integration site family, member 9","NP_001341531.1//transmembrane protein 269 [Homo sapiens]","1//3"]
[51021,2651,54.05,53.36,-0.0185359514374275,0.834175472172352,"*",0.756262,"MRPS16","GO:0005840//ribosome;GO:0005829//cytosol;GO:0005763//mitochondrial small ribosomal subunit;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0003735//structural constituent of ribosome","GO:0032543//mitochondrial translation;GO:0006412//translation;GO:0070126//mitochondrial translational termination;GO:0070125//mitochondrial translational elongation","K02959//small subunit ribosomal protein S16","NP_057149.1//28S ribosomal protein S16, mitochondrial [Homo sapiens]","3//A2MP1"]
[9741,1783,126.29,124.68,-0.0185103468913739,0.782863052683826,"*",0.691168,"LAPTM4A","GO:0016021//integral component of membrane","NA","NA","K12387//lysosomal-associated transmembrane protein","EDM03082.1//lysosomal-associated protein transmembrane 4A [Rattus norvegicus]",4]
[10569,3570,11.01,10.87,-0.0184625285370599,0.92509391699316,"*",0.872104,"SLU7","NA","NA","NA","K12819//pre-mRNA-processing factor SLU7","XP_004404827.1//PREDICTED: pre-mRNA-splicing factor SLU7 [Odobenus rosmarus divergens]",4]
[7150,3750,27.64,27.29,-0.018385221114118,0.861418143382854,"*",0.791314,"TOP1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0000932//P-body;GO:0009330//DNA topoisomerase complex (ATP-hydrolyzing);GO:0043204//perikaryon;GO:0005730//nucleolus;GO:0031298//replication fork protection complex;GO:0001650//fibrillar center;GO:0032993//protein-DNA complex","GO:0003723//RNA binding;GO:0003677//DNA binding;GO:0003917//DNA topoisomerase type I activity;GO:0001046//core promoter sequence-specific DNA binding;GO:0005524//ATP binding;GO:0003690//double-stranded DNA binding;GO:0003697//single-stranded DNA binding;GO:0019904//protein domain specific binding;GO:0004674//protein serine/threonine kinase activity;GO:0097100//supercoiled DNA binding;GO:0003682//chromatin binding","GO:0007623//circadian rhythm;GO:0042493//response to drug;GO:0016925//protein sumoylation;GO:0016310//phosphorylation;GO:0007059//chromosome segregation;GO:0006338//chromatin remodeling;GO:0006260//DNA replication;GO:0016032//viral process;GO:0040016//embryonic cleavage;GO:0018105//peptidyl-serine phosphorylation;GO:0012501//programmed cell death;GO:0032922//circadian regulation of gene expression;GO:0006265//DNA topological change","K03163//DNA topoisomerase I [EC:5.99.1.2]","NP_003277.1//DNA topoisomerase 1 [Homo sapiens]","3//A2MP1"]
[10365,2814,7.17,7.08,-0.0182237586189073,0.954120494656088,"*",0.910936,"KLF2","GO:0000790//nuclear chromatin","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0071409//cellular response to cycloheximide;GO:0071498//cellular response to fluid shear stress;GO:0032715//negative regulation of interleukin-6 production;GO:0071356//cellular response to tumor necrosis factor;GO:0045893//positive regulation of transcription, DNA-templated;GO:0071499//cellular response to laminar fluid shear stress;GO:0071347//cellular response to interleukin-1;GO:0070301//cellular response to hydrogen peroxide;GO:0000902//cell morphogenesis;GO:0040029//regulation of gene expression, epigenetic;GO:0043249//erythrocyte maturation;GO:0051247//positive regulation of protein metabolic process;GO:1901653//cellular response to peptide;GO:0006351//transcription, DNA-templated;GO:0001701//in utero embryonic development;GO:0036003//positive regulation of transcription from RNA polymerase II promoter in response to stress;GO:0035264//multicellular organism growth;GO:0060509//Type I pneumocyte differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045429//positive regulation of nitric oxide biosynthetic process","K17845//krueppel-like factor 2","NP_057354.1//Krueppel-like factor 2 [Homo sapiens]","3//A2MP1"]
[64114,2330,70.23,69.35,-0.0181915526222041,0.831782927914852,"*",0.753416,"TMBIM1","GO:0005765//lysosomal membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0010008//endosome membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane;GO:0005886//plasma membrane","GO:0005123//death receptor binding","GO:1903077//negative regulation of protein localization to plasma membrane;GO:2000504//positive regulation of blood vessel remodeling;GO:0043312//neutrophil degranulation;GO:0043086//negative regulation of catalytic activity;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:1902045//negative regulation of Fas signaling pathway","K06890//uncharacterized protein","BAG62294.1//unnamed protein product [Homo sapiens];NP_071435.2//protein lifeguard 3 isoform 1 [Homo sapiens]","1//3;5"]
[2558,2820,38.84,38.36,-0.0179404804010615,0.742991166739099,"*",0.642152,"GABRA5","GO:0030425//dendrite;GO:0044297//cell body;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0045202//synapse;GO:0005886//plasma membrane","GO:0005230//extracellular ligand-gated ion channel activity;GO:0004890//GABA-A receptor activity","GO:0060384//innervation;GO:0007214//gamma-aminobutyric acid signaling pathway;GO:0043524//negative regulation of neuron apoptotic process;GO:0001662//behavioral fear response;GO:0006821//chloride transport;GO:0008306//associative learning;GO:0060119//inner ear receptor cell development;GO:0007605//sensory perception of sound;GO:0090102//cochlea development","K05175//gamma-aminobutyric acid receptor subunit alpha","XP_012419323.1//PREDICTED: gamma-aminobutyric acid receptor subunit alpha-5 isoform X1 [Odobenus rosmarus divergens]","1//3;3//A2MP1"]
[51118,2067,38.08,37.61,-0.0179171722676371,0.883381939631305,"*",0.818956,"UTP11","GO:0005654//nucleoplasm;GO:0005615//extracellular space;GO:0032040//small-subunit processome;GO:0005730//nucleolus;GO:0019013//viral nucleocapsid;GO:0005737//cytoplasm","GO:0003723//RNA binding","GO:0007399//nervous system development;GO:0043065//positive regulation of apoptotic process;GO:0042274//ribosomal small subunit biogenesis;GO:0006364//rRNA processing","K14769//U3 small nucleolar RNA-associated protein 11","NP_057121.2//probable U3 small nucleolar RNA-associated protein 11 [Homo sapiens]","3//A2MP1"]
[116835,3072,2.44,2.41,-0.0178480013329246,0.942283843121746,"*",0.894916,"HSPA12B","NA","GO:0005524//ATP binding","NA","K10609//cullin 4;K22016//mucin-3/17","XP_018872826.1//PREDICTED: heat shock 70 kDa protein 12B isoform X1 [Gorilla gorilla gorilla];AAH90857.1//HSPA12B protein, partial [Homo sapiens]","4;1//3"]
[10953,2066,35.14,34.71,-0.0177628261797299,0.889554813139472,"*",0.827296,"TOMM34","GO:0016020//membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005741//mitochondrial outer membrane","GO:0031072//heat shock protein binding","GO:0006626//protein targeting to mitochondrion","K17766//mitochondrial import receptor subunit TOM34","NP_006800.2//mitochondrial import receptor subunit TOM34 [Homo sapiens]",4]
[22846,6030,3.27,3.23,-0.0177564708041576,0.953720623417514,"*",0.910196,"VASH1","GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0045177//apical part of cell;GO:0005737//cytoplasm","NA","GO:0009611//response to wounding;GO:0001937//negative regulation of endothelial cell proliferation;GO:0060716//labyrinthine layer blood vessel development;GO:0001525//angiogenesis;GO:0010596//negative regulation of endothelial cell migration;GO:0016525//negative regulation of angiogenesis;GO:0007050//cell cycle arrest;GO:0045765//regulation of angiogenesis;GO:1901491//negative regulation of lymphangiogenesis;GO:2000772//regulation of cellular senescence;GO:0043537//negative regulation of blood vessel endothelial cell migration","K16628//collagen, type VII, alpha","NP_055724.1//vasohibin-1 [Homo sapiens]",4]
[79084,2423,34.43,34.01,-0.0177071748620737,0.68633292014807,"*",0.568736,"WDR77","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0034709//methylosome;GO:0005737//cytoplasm","GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0016274//protein-arginine N-methyltransferase activity;GO:0008327//methyl-CpG binding","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0060770//negative regulation of epithelial cell proliferation involved in prostate gland development;GO:0060528//secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development;GO:0000387//spliceosomal snRNP assembly;GO:0008284//positive regulation of cell proliferation","K13221//methylosome protein 50","NP_001303993.1//methylosome protein 50 isoform 4 [Homo sapiens];NP_077007.1//methylosome protein 50 isoform 2 [Homo sapiens];NP_001303991.1//methylosome protein 50 isoform 1 [Homo sapiens];NP_001303992.1//methylosome protein 50 isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[5495,3231,11.5,11.36,-0.0176710263270555,0.299034305069519,"*",0.1750326,"PPM1B","GO:0016020//membrane;GO:0005730//nucleolus;GO:0005829//cytosol","GO:0000287//magnesium ion binding;GO:0004722//protein serine/threonine phosphatase activity;GO:0030145//manganese ion binding","GO:0035970//peptidyl-threonine dephosphorylation;GO:0042347//negative regulation of NF-kappaB import into nucleus;GO:0006499//N-terminal protein myristoylation;GO:0006470//protein dephosphorylation;GO:0032688//negative regulation of interferon-beta production;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0050687//negative regulation of defense response to virus","K04461//protein phosphatase 1B [EC:3.1.3.16]","NP_001028729.1//protein phosphatase 1B isoform 5 [Homo sapiens];NP_808907.1//protein phosphatase 1B isoform 2 [Homo sapiens];NP_002697.1//protein phosphatase 1B isoform 1 [Homo sapiens]","3//A2MP1;2//1;5"]
[5284,4295,0.83,0.82,-0.0174874267288411,1.02199214101573,"*",0.99269,"PIGR","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0043235//receptor complex;GO:0035577//azurophil granule membrane","GO:0001792//polymeric immunoglobulin receptor activity","GO:0043113//receptor clustering;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0001895//retina homeostasis;GO:0043312//neutrophil degranulation;GO:0002415//immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor;GO:0038093//Fc receptor signaling pathway;GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste","K13073//polymeric immunoglobulin receptor","NP_002635.2//polymeric immunoglobulin receptor precursor [Homo sapiens]","3//A2MP1"]
[152185,5280,2.52,2.49,-0.0172779914318355,0.966095924538155,"*",0.926482,"SPICE1","GO:0005814//centriole;GO:0005819//spindle;GO:0005813//centrosome","NA","GO:0090307//mitotic spindle assembly;GO:0051301//cell division;GO:0051310//metaphase plate congression;GO:0046599//regulation of centriole replication","K16490//spindle and centriole-associated protein 1","NP_001318008.1//spindle and centriole-associated protein 1 isoform b [Homo sapiens];XP_016861265.1//PREDICTED: spindle and centriole-associated protein 1 isoform X2 [Homo sapiens]","1//3;3//A2MP1"]
[51155,1612,152.95,151.14,-0.0171745789901674,0.781338089509894,"*",0.689626,"JPT1","GO:0005634//nucleus;GO:0031965//nuclear membrane;GO:0005730//nucleolus;GO:0005737//cytoplasm","NA","NA","NA","XP_009189479.2//jupiter microtubule associated homolog 1 isoform X1 [Papio anubis];XP_008511468.1//PREDICTED: hematological and neurological expressed 1 protein isoform X1 [Equus przewalskii];EAW89245.1//hematological and neurological expressed 1, isoform CRA_b [Homo sapiens];NP_001002032.1//jupiter microtubule associated homolog 1 isoform 2 [Homo sapiens];XP_014337755.1//PREDICTED: hematological and neurological expressed 1 protein isoform X1 [Bos mutus];XP_017740254.1//PREDICTED: hematological and neurological expressed 1 protein isoform X1 [Rhinopithecus bieti]","1//3;3//A2MP1;2//1"]
[113878,2662,39.83,39.36,-0.0171252590249461,0.94480055642561,"*",0.898844,"DTX2","GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0005737//cytoplasm","GO:0008270//zinc ion binding;GO:0016740//transferase activity","GO:0016567//protein ubiquitination;GO:0007219//Notch signaling pathway","K06058//deltex [EC:2.3.2.27]","NP_001096066.1//probable E3 ubiquitin-protein ligase DTX2 isoform b [Homo sapiens];XP_014988767.1//PREDICTED: probable E3 ubiquitin-protein ligase DTX2 isoform X1 [Macaca mulatta];XP_011785482.1//PREDICTED: probable E3 ubiquitin-protein ligase DTX2 isoform X1 [Colobus angolensis palliatus]","1//3;2//1"]
[2962,2551,32.3,31.92,-0.0170735133589412,0.901502991490787,"*",0.842302,"GTF2F1","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005674//transcription factor TFIIF complex;GO:0043234//protein complex;GO:0030054//cell junction;GO:0005669//transcription factor TFIID complex","GO:0003723//RNA binding;GO:0003677//DNA binding;GO:0003713//transcription coactivator activity;GO:0019904//protein domain specific binding;GO:0019211//phosphatase activator activity;GO:0019903//protein phosphatase binding;GO:0008134//transcription factor binding","GO:0016070//RNA metabolic process;GO:0042795//snRNA transcription from RNA polymerase II promoter;GO:0000398//mRNA splicing, via spliceosome;GO:0006370//7-methylguanosine mRNA capping;GO:0050434//positive regulation of viral transcription;GO:0006366//transcription from RNA polymerase II promoter;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0009615//response to virus","K03138//transcription initiation factor TFIIF subunit alpha","NP_002087.2//general transcription factor IIF subunit 1 [Homo sapiens]","2//1"]
[64423,4296,55.38,54.73,-0.0170331971594422,0.473637909191176,"*",0.322598,"INF2","GO:0048471//perinuclear region of cytoplasm","GO:0003779//actin binding;GO:0017048//Rho GTPase binding","GO:0030036//actin cytoskeleton organization;GO:0090140//regulation of mitochondrial fission","K01939//adenylosuccinate synthase [EC:6.3.4.4];K04512//dishevelled associated activator of morphogenesis;K05741//diaphanous 2","XP_005268061.1//PREDICTED: inverted formin-2 isoform X1 [Homo sapiens];XP_005268062.1//PREDICTED: inverted formin-2 isoform X2 [Homo sapiens]","3//A2MP1;2//1"]
[6627,1103,51.12,50.52,-0.0170331971594419,0.912563873324888,"*",0.856864,"SNRPA1","GO:0005654//nucleoplasm;GO:0005686//U2 snRNP;GO:0016607//nuclear speck;GO:0071013//catalytic step 2 spliceosome;GO:0005681//spliceosomal complex;GO:0030532//small nuclear ribonucleoprotein complex;GO:0030529//intracellular ribonucleoprotein complex;GO:0019013//viral nucleocapsid","GO:0030620//U2 snRNA binding;GO:0003723//RNA binding","GO:0006397//mRNA processing;GO:0000398//mRNA splicing, via spliceosome;GO:0008380//RNA splicing;GO:0035722//interleukin-12-mediated signaling pathway","K11092//U2 small nuclear ribonucleoprotein A'","XP_014998567.1//PREDICTED: U2 small nuclear ribonucleoprotein A' isoform X1 [Macaca mulatta]","3//A2MP1"]
[81929,2855,18.11,17.9,-0.0168269587985492,0.747902217655572,"*",0.647052,"SEH1L","GO:0005765//lysosomal membrane;GO:0043657//host cell;GO:0005635//nuclear envelope;GO:0061700//GATOR2 complex;GO:0005829//cytosol;GO:0031080//nuclear pore outer ring;GO:0000777//condensed chromosome kinetochore;GO:0000776//kinetochore","NA","GO:0006406//mRNA export from nucleus;GO:0007077//mitotic nuclear envelope disassembly;GO:0034198//cellular response to amino acid starvation;GO:0016925//protein sumoylation;GO:0006999//nuclear pore organization;GO:0006110//regulation of glycolytic process;GO:0032008//positive regulation of TOR signaling;GO:0051028//mRNA transport;GO:0007080//mitotic metaphase plate congression;GO:0050830//defense response to Gram-positive bacterium;GO:0015031//protein transport;GO:1904263//positive regulation of TORC1 signaling;GO:0051315//attachment of mitotic spindle microtubules to kinetochore;GO:0060964//regulation of gene silencing by miRNA;GO:0006409//tRNA export from nucleus;GO:0034629//cellular protein complex localization;GO:0016032//viral process;GO:0002534//cytokine production involved in inflammatory response;GO:1900034//regulation of cellular response to heat;GO:0007062//sister chromatid cohesion;GO:0051301//cell division;GO:0019083//viral transcription;GO:0075733//intracellular transport of virus","K14299//nucleoporin SEH1","NP_001013455.1//nucleoporin SEH1 isoform 1 [Homo sapiens];NP_112493.2//nucleoporin SEH1 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[118812,2367,6.05,5.98,-0.0167896579638516,1.00588007043895,"*",0.972632,"MORN4","GO:0032426//stereocilium tip;GO:0005737//cytoplasm;GO:0032433//filopodium tip","NA","GO:0048678//response to axon injury","K19755//radial spoke head protein 1;K12581//CCR4-NOT transcription complex subunit 7/8;K19530//junctophilin","EGV99291.1//MORN repeat-containing protein 4 [Cricetulus griseus]","1//3;3//A2MP1"]
[6793,6039,6.95,6.87,-0.0167028787927697,0.930002955392059,"*",0.878362,"STK10","GO:0070062//extracellular exosome;GO:0035579//specific granule membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity","GO:0023014//signal transduction by protein phosphorylation;GO:0071593//lymphocyte aggregation;GO:0007346//regulation of mitotic cell cycle;GO:0006468//protein phosphorylation;GO:0032147//activation of protein kinase activity;GO:2000401//regulation of lymphocyte migration;GO:0046777//protein autophosphorylation;GO:0043312//neutrophil degranulation;GO:0031098//stress-activated protein kinase signaling cascade;GO:0007049//cell cycle;GO:0042981//regulation of apoptotic process","K08837//serine/threonine kinase 10 [EC:2.7.11.1]","NP_005981.3//serine/threonine-protein kinase 10 [Homo sapiens]","3//A2MP1"]
[92856,3082,47.04,46.5,-0.0166573439536082,0.81591406196477,"*",0.733628,"IMP4","GO:0005654//nucleoplasm;GO:0032040//small-subunit processome;GO:0005730//nucleolus;GO:0034457//Mpp10 complex;GO:0001650//fibrillar center","GO:0030515//snoRNA binding;GO:0042134//rRNA primary transcript binding","GO:0006364//rRNA processing","K14561//U3 small nucleolar ribonucleoprotein protein IMP4","XP_003281794.1//PREDICTED: U3 small nucleolar ribonucleoprotein protein IMP4 [Nomascus leucogenys];XP_010371582.1//PREDICTED: U3 small nucleolar ribonucleoprotein protein IMP4 isoform X2 [Rhinopithecus roxellana];EAW55615.1//IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast), isoform CRA_c [Homo sapiens]","1//3;2//1"]
[79762,2990,2.64,2.61,-0.0164881227885691,0.988450941443486,"*",0.954232,"C1orf115","GO:0016021//integral component of membrane","NA","NA","K05740//diaphanous 1;K05747//Wiskott-Aldrich syndrome protein;K10367//formin 1","XP_001172852.3//PREDICTED: uncharacterized protein C1orf115 homolog [Pan troglodytes]",4]
[2298,2204,0.88,0.87,-0.0164881227885689,0.939334049907579,"*",0.890762,"FOXD4","GO:0005634//nucleus","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0008301//DNA binding, bending","GO:0009653//anatomical structure morphogenesis;GO:0030154//cell differentiation;GO:0006351//transcription, DNA-templated","K09397//forkhead box protein D","AAQ76878.1//FOXD4 [Homo sapiens]",4]
[149175,2674,22.89,22.63,-0.0164808782887942,0.758616474268416,"*",0.658886,"MANEAL","GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0016798//hydrolase activity, acting on glycosyl bonds","NA","K15538//glycoprotein endo-alpha-1,2-mannosidase [EC:3.2.1.130]","XP_011761821.1//PREDICTED: glycoprotein endo-alpha-1,2-mannosidase-like protein isoform X2 [Macaca nemestrina];NP_001026910.1//glycoprotein endo-alpha-1,2-mannosidase-like protein isoform 1 precursor [Homo sapiens];NP_001106954.1//glycoprotein endo-alpha-1,2-mannosidase-like protein isoform 3 precursor [Homo sapiens]","1//3;2//1"]
[6428,3144,63.59,62.87,-0.0164281457152403,0.823983020612117,"*",0.743256,"SRSF3","NA","NA","NA","K12892//splicing factor, arginine/serine-rich 3","OCT91642.1//hypothetical protein XELAEV_18014700mg [Xenopus laevis]",4]
[6487,2283,1.77,1.75,-0.0163944382506686,0.850852372443046,"*",0.778572,"ST3GAL3","GO:0032580//Golgi cisterna membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0000139//Golgi membrane","GO:0003836//beta-galactoside (CMP) alpha-2,3-sialyltransferase activity;GO:0008373//sialyltransferase activity;GO:0008118//N-acetyllactosaminide alpha-2,3-sialyltransferase activity","GO:0006486//protein glycosylation;GO:0018146//keratan sulfate biosynthetic process;GO:0018279//protein N-linked glycosylation via asparagine;GO:0009311//oligosaccharide metabolic process;GO:0016266//O-glycan processing","K00781//neolactotetraosylceramide alpha-2,3-sialyltransferase (sialyltransferase 6) [EC:2.4.99.6]","NP_001257390.1//CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform m [Homo sapiens];NP_777626.1//CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform d [Homo sapiens];XP_012577841.1//PREDICTED: CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X5 [Condylura cristata];NP_001257391.1//CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform n [Homo sapiens];NP_777629.1//CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform g [Homo sapiens];NP_777628.2//CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform f [Homo sapiens];NP_001337548.1//CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform s [Homo sapiens];NP_001257394.1//CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform q [Homo sapiens];NP_001257395.1//CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform r [Homo sapiens];XP_011540276.1//PREDICTED: CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X3 [Homo sapiens];NP_777631.2//CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform i [Homo sapiens];NP_001257388.1//CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform k [Homo sapiens];NP_777623.2//CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform a [Homo sapiens];NP_001257389.1//CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform l [Homo sapiens];XP_012577840.1//PREDICTED: CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X4 [Condylura cristata];NP_006270.1//CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform j [Homo sapiens];NP_777624.1//CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform b [Homo sapiens];NP_001257392.1//CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform o [Homo sapiens];NP_001257393.1//CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform p [Homo sapiens];NP_001337549.1//CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform t [Homo sapiens]","4;1//3;3//A2MP1;2//1"]
[55471,2068,11.51,11.38,-0.0163872758256483,0.983494165228114,"*",0.948708,"NDUFAF7","GO:0005759//mitochondrial matrix;GO:0005615//extracellular space;GO:0005739//mitochondrion","GO:0008168//methyltransferase activity;GO:0035243//protein-arginine omega-N symmetric methyltransferase activity;GO:0019899//enzyme binding","GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0046034//ATP metabolic process;GO:0019918//peptidyl-arginine methylation, to symmetrical-dimethyl arginine","K18164//NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 7","NP_001336956.1//protein arginine methyltransferase NDUFAF7, mitochondrial isoform 6 [Homo sapiens];NP_001336953.1//protein arginine methyltransferase NDUFAF7, mitochondrial isoform 4 [Homo sapiens];NP_001077415.1//protein arginine methyltransferase NDUFAF7, mitochondrial isoform 3 [Homo sapiens];NP_653337.1//protein arginine methyltransferase NDUFAF7, mitochondrial isoform 1 [Homo sapiens];NP_001336954.1//protein arginine methyltransferase NDUFAF7, mitochondrial isoform 5 [Homo sapiens]","4;1//3"]
[23383,4853,7.97,7.88,-0.0163840945340956,0.924452540188654,"*",0.87121,"MAU2","NA","NA","NA","K11266//MAternally affected uncoordination","XP_017356856.1//PREDICTED: MAU2 chromatid cohesion factor homolog isoform X1 [Cebus capucinus imitator]","3//A2MP1"]
[10055,2486,138.26,136.7,-0.0163705878137576,0.543364568231489,"*",0.389104,"SAE1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031510//SUMO activating enzyme complex;GO:0005737//cytoplasm","GO:0008022//protein C-terminus binding;GO:0046982//protein heterodimerization activity;GO:0043008//ATP-dependent protein binding;GO:0044388//small protein activating enzyme binding;GO:0008047//enzyme activator activity;GO:0004839//ubiquitin activating enzyme activity","GO:0016925//protein sumoylation;GO:1903955//positive regulation of protein targeting to mitochondrion;GO:0016567//protein ubiquitination","K10684//ubiquitin-like 1-activating enzyme E1 A [EC:6.2.1.45]","XP_016791806.1//PREDICTED: SUMO-activating enzyme subunit 1 isoform X1 [Pan troglodytes];XP_011825127.1//PREDICTED: SUMO-activating enzyme subunit 1 isoform X1 [Mandrillus leucophaeus];XP_016791809.1//PREDICTED: SUMO-activating enzyme subunit 1 isoform X4 [Pan troglodytes]","1//3;2//1"]
[5725,3335,180.17,178.14,-0.0163473096936379,0.713562485390579,"*",0.599296,"PTBP1","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus","GO:0003723//RNA binding;GO:0036002//pre-mRNA binding;GO:0008187//poly-pyrimidine tract binding","GO:0016070//RNA metabolic process;GO:0006397//mRNA processing;GO:0075522//IRES-dependent viral translational initiation;GO:0000398//mRNA splicing, via spliceosome;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0033119//negative regulation of RNA splicing;GO:0051148//negative regulation of muscle cell differentiation;GO:0008380//RNA splicing;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0048025//negative regulation of mRNA splicing, via spliceosome","K13218//polypyrimidine tract-binding protein 1","NP_114367.1//polypyrimidine tract-binding protein 1 isoform b [Homo sapiens];NP_002810.1//polypyrimidine tract-binding protein 1 isoform a [Homo sapiens];NP_114368.1//polypyrimidine tract-binding protein 1 isoform c [Homo sapiens]","4;3//A2MP1"]
[25970,3204,26.77,26.47,-0.0162589441453793,0.187855905140962,"*",0.0992788,"SH2B1","GO:0016020//membrane;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005622//intracellular","GO:0035591//signaling adaptor activity;GO:0004871//signal transducer activity","GO:0030032//lamellipodium assembly;GO:0007165//signal transduction;GO:0007596//blood coagulation;GO:2000278//regulation of DNA biosynthetic process;GO:0035556//intracellular signal transduction;GO:0045840//positive regulation of mitotic nuclear division","K12459//SH2B adaptor protein 1/3","XP_015297999.1//PREDICTED: SH2B adapter protein 1 isoform X1 [Macaca fascicularis];NP_001139284.1//SH2B adapter protein 1 isoform 2 [Homo sapiens];XP_012320016.1//SH2B adapter protein 1 isoform X2 [Aotus nancymaae];XP_012320020.1//SH2B adapter protein 1 isoform X4 [Aotus nancymaae];XP_012320015.1//SH2B adapter protein 1 isoform X1 [Aotus nancymaae]","1//3;2//1"]
[100506581,1094,3.57,3.53,-0.0162558907579192,0.840264719565068,"*",0.76436,"C16orf95","NA","NA","NA","NA","NP_001182053.1//uncharacterized protein C16orf95 isoform 1 [Homo sapiens];XP_007992480.1//PREDICTED: uncharacterized protein C16orf95 homolog isoform X7 [Chlorocebus sabaeus];NP_001182054.1//uncharacterized protein C16orf95 isoform 2 [Homo sapiens]","1//3"]
[9343,4096,74.21,73.38,-0.0162267024527462,0.700939263575762,"*",0.585842,"EFTUD2","GO:0016020//membrane;GO:0031012//extracellular matrix;GO:0005654//nucleoplasm;GO:0016607//nuclear speck;GO:0046540//U4/U6 x U5 tri-snRNP complex;GO:0071013//catalytic step 2 spliceosome;GO:0005681//spliceosomal complex;GO:0030529//intracellular ribonucleoprotein complex;GO:0005829//cytosol;GO:0015030//Cajal body;GO:0019013//viral nucleocapsid","GO:0003723//RNA binding;GO:0003746//translation elongation factor activity;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0006397//mRNA processing;GO:0000398//mRNA splicing, via spliceosome;GO:0035690//cellular response to drug;GO:0008380//RNA splicing;GO:0042220//response to cocaine","K12852//116 kDa U5 small nuclear ribonucleoprotein component","NP_001245283.1//116 kDa U5 small nuclear ribonucleoprotein component isoform c [Homo sapiens];XP_011795512.1//PREDICTED: 116 kDa U5 small nuclear ribonucleoprotein component isoform X1 [Colobus angolensis palliatus];NP_004238.3//116 kDa U5 small nuclear ribonucleoprotein component isoform a [Homo sapiens]","1//3;3//A2MP1"]
[2101,2287,24.33,24.06,-0.0160996777623527,0.930590828893307,"*",0.879092,"ESRRA","NA","NA","NA","K08552//estrogen-related receptor alpha","XP_007992093.1//PREDICTED: steroid hormone receptor ERR1 isoform X1 [Chlorocebus sabaeus]","1//3;4"]
[7982,2505,13.54,13.39,-0.016071778250686,1.01044567997412,"*",0.977616,"ST7","GO:0016021//integral component of membrane","NA","NA","K09291//nucleoprotein TPR","NP_068708.1//suppressor of tumorigenicity 7 protein isoform b [Homo sapiens];NP_060882.2//suppressor of tumorigenicity 7 protein isoform a [Homo sapiens]","3//A2MP1;2//1"]
[51603,3233,16.42,16.24,-0.0159024945926288,0.474125692293561,"*",0.323138,"METTL13","NA","GO:0008168//methyltransferase activity","NA","K01415//endothelin-converting enzyme [EC:3.4.24.71];K08513//vesicle-associated membrane protein 4","BAD97213.1//KIAA0859 protein (Fragment) variant, partial [Homo sapiens];NP_057019.3//methyltransferase-like protein 13 isoform 1 [Homo sapiens];NP_001007240.1//methyltransferase-like protein 13 isoform 3 [Homo sapiens]","4;1//3;2//1"]
[80013,2367,6.52,6.45,-0.015572803920461,0.972286631222309,"*",0.934184,"MINDY3","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane","GO:0016807//cysteine-type carboxypeptidase activity;GO:0036459//thiol-dependent ubiquitinyl hydrolase activity;GO:1990380//Lys48-specific deubiquitinase activity","GO:0006915//apoptotic process","K08742//E3 ubiquitin-protein ligase SIAH2 [EC:2.3.2.27];K20465//oxysterol-binding protein-related protein 9/10/11","NP_079224.1//ubiquitin carboxyl-terminal hydrolase MINDY-3 isoform a [Homo sapiens];CAG33596.1//FLJ13397 [Homo sapiens]","1//3;3//A2MP1"]
[80347,2574,81.45,80.58,-0.0154928932642816,0.862748288729997,"*",0.79313,"COASY","GO:0005759//mitochondrial matrix;GO:0070062//extracellular exosome;GO:0005741//mitochondrial outer membrane","GO:0005524//ATP binding;GO:0004140//dephospho-CoA kinase activity;GO:0004595//pantetheine-phosphate adenylyltransferase activity","GO:0009108//coenzyme biosynthetic process;GO:0015937//coenzyme A biosynthetic process","K02318//phosphopantetheine adenylyltransferase / dephospho-CoA kinase [EC:2.7.7.3 2.7.1.24]","NP_001035997.2//bifunctional coenzyme A synthase isoform c [Homo sapiens]","6;3//A2MP1;2//1"]
[65080,1772,27.29,27,-0.0154129873359473,0.937799177325581,"*",0.888602,"MRPL44","GO:0005840//ribosome;GO:0005634//nucleus;GO:0005762//mitochondrial large ribosomal subunit;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0005886//plasma membrane","GO:0003723//RNA binding;GO:0004525//ribonuclease III activity;GO:0003725//double-stranded RNA binding","GO:0006396//RNA processing;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic;GO:0070126//mitochondrial translational termination;GO:0070125//mitochondrial translational elongation","K17425//large subunit ribosomal protein L44 [EC:3.1.26.-]","NP_075066.1//39S ribosomal protein L44, mitochondrial [Homo sapiens]","3//A2MP1"]
[143903,2382,0.95,0.94,-0.0152667566533105,0.946890910382011,"*",0.901544,"LAYN","GO:0001726//ruffle;GO:0009986//cell surface;GO:0005925//focal adhesion;GO:0016021//integral component of membrane","GO:0030246//carbohydrate binding;GO:0005540//hyaluronic acid binding","NA","K10077//layilin","NP_849156.1//layilin isoform 2 precursor [Homo sapiens];NP_001245320.1//layilin isoform 3 [Homo sapiens];NP_001245319.1//layilin isoform 1 precursor [Homo sapiens]","1//3;4"]
[55325,2379,6.66,6.59,-0.0152437120632105,0.972860813285575,"*",0.935162,"UFSP2","GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005737//cytoplasm","GO:0071567//UFM1 hydrolase activity;GO:0016790//thiolester hydrolase activity","GO:0006508//proteolysis;GO:0033146//regulation of intracellular estrogen receptor signaling pathway","K01376//UFM1-specific protease 2 [EC:3.4.22.-]","XP_012640380.2//ufm1-specific protease 2 isoform X1 [Microcebus murinus]","3//A2MP1"]
[55245,2460,15.26,15.1,-0.0152064126220892,0.941181001978109,"*",0.893574,"UQCC1","GO:0031410//cytoplasmic vesicle;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","NA","GO:0034551//mitochondrial respiratory chain complex III assembly;GO:0070131//positive regulation of mitochondrial translation","K17662//cytochrome b pre-mRNA-processing protein 3","NP_955781.2//ubiquinol-cytochrome-c reductase complex assembly factor 1 isoform b [Homo sapiens];NP_001171906.1//ubiquinol-cytochrome-c reductase complex assembly factor 1 isoform c [Homo sapiens];NP_060714.3//ubiquinol-cytochrome-c reductase complex assembly factor 1 isoform a [Homo sapiens]","4;1//3;2//1"]
[7917,3662,65.03,64.35,-0.015165275332193,0.847260697071531,"*",0.773376,"BAG6","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0071818//BAT3 complex;GO:0005829//cytosol","GO:0043022//ribosome binding;GO:0031593//polyubiquitin modification-dependent protein binding;GO:0042802//identical protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0005102//receptor binding;GO:1990381//ubiquitin-specific protease binding;GO:0051787//misfolded protein binding;GO:0070628//proteasome binding;GO:0030544//Hsp70 protein binding","GO:0030324//lung development;GO:0018393//internal peptidyl-lysine acetylation;GO:1904378//maintenance of unfolded protein involved in ERAD pathway;GO:0045861//negative regulation of proteolysis;GO:0001822//kidney development;GO:0042127//regulation of cell proliferation;GO:1904379//protein localization to cytosolic proteasome complex involved in ERAD pathway;GO:0002429//immune response-activating cell surface receptor signaling pathway;GO:0007283//spermatogenesis;GO:0007420//brain development;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0010498//proteasomal protein catabolic process;GO:0006810//transport;GO:0030154//cell differentiation;GO:0061857//endoplasmic reticulum stress-induced pre-emptive quality control;GO:0071712//ER-associated misfolded protein catabolic process;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0043066//negative regulation of apoptotic process;GO:0006915//apoptotic process;GO:0007130//synaptonemal complex assembly;GO:0030101//natural killer cell activation;GO:0016569//covalent chromatin modification;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0071816//tail-anchored membrane protein insertion into ER membrane;GO:1904294//positive regulation of ERAD pathway;GO:0009790//embryo development;GO:0050821//protein stabilization;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process","K19475//WAS/WASL-interacting protein;K05746//enabled","AAD18085.1//BAT3 [Homo sapiens];XP_008573291.1//PREDICTED: large proline-rich protein BAG6 isoform X2 [Galeopterus variegatus];NP_001186626.1//large proline-rich protein BAG6 isoform c [Homo sapiens];XP_017715016.1//PREDICTED: LOW QUALITY PROTEIN: large proline-rich protein BAG6 [Rhinopithecus bieti]","1//3;3//A2MP1;2//1"]
[55191,2453,19.25,19.05,-0.0150674480889417,0.937229350171912,"*",0.887358,"NADSYN1","GO:0005829//cytosol","GO:0005524//ATP binding;GO:0003952//NAD+ synthase (glutamine-hydrolyzing) activity;GO:0016810//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds","GO:0009435//NAD biosynthetic process","K01950//NAD+ synthase (glutamine-hydrolysing) [EC:6.3.5.1]","XP_003278076.1//PREDICTED: glutamine-dependent NAD(+) synthetase [Nomascus leucogenys]",4]
[22838,4153,22.31,22.08,-0.0149503414659716,0.899461713059802,"*",0.839888,"RNF44","NA","GO:0061630//ubiquitin protein ligase activity;GO:0046872//metal ion binding","GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process","K19041//E3 ubiquitin-protein ligase RNF38/44 [EC:2.3.2.27]","NP_055716.1//RING finger protein 44 [Homo sapiens]",4]
[9167,1163,92.34,91.39,-0.014919419835739,0.87359573541384,"*",0.80611,"COX7A2L","GO:0005730//nucleolus;GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0005746//mitochondrial respiratory chain","GO:0004129//cytochrome-c oxidase activity","GO:0006123//mitochondrial electron transport, cytochrome c to oxygen","K02270//cytochrome c oxidase subunit 7a","NP_001305966.1//cytochrome c oxidase subunit 7A-related protein, mitochondrial isoform b [Homo sapiens];XP_004770979.1//PREDICTED: cytochrome c oxidase subunit 7A-related protein, mitochondrial [Mustela putorius furo];EPQ06834.1//Cytochrome c oxidase subunit 7A-related protein, mitochondrial [Myotis brandtii]","1//3;3//A2MP1"]
[3551,4075,9.76,9.66,-0.0148579587271131,0.926339321385902,"*",0.873684,"IKBKB","GO:0005634//nucleus;GO:0045121//membrane raft;GO:0005829//cytosol;GO:0005622//intracellular;GO:0009898//cytoplasmic side of plasma membrane;GO:0035631//CD40 receptor complex;GO:0008385//IkappaB kinase complex","GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0019901//protein kinase binding;GO:0097110//scaffold protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0008384//IkappaB kinase activity;GO:0004672//protein kinase activity","GO:0042325//regulation of phosphorylation;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0030866//cortical actin cytoskeleton organization;GO:0070498//interleukin-1-mediated signaling pathway;GO:0071356//cellular response to tumor necrosis factor;GO:0010803//regulation of tumor necrosis factor-mediated signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0035509//negative regulation of myosin-light-chain-phosphatase activity;GO:0045087//innate immune response;GO:0009653//anatomical structure morphogenesis;GO:0072659//protein localization to plasma membrane;GO:0070423//nucleotide-binding oligomerization domain containing signaling pathway;GO:0050852//T cell receptor signaling pathway;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0006468//protein phosphorylation;GO:0043066//negative regulation of apoptotic process;GO:0006954//inflammatory response;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0018105//peptidyl-serine phosphorylation;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:1903347//negative regulation of bicellular tight junction assembly;GO:1903140//regulation of establishment of endothelial barrier;GO:0009615//response to virus;GO:0051403//stress-activated MAPK cascade","K07209//inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]","NP_001229707.1//inhibitor of nuclear factor kappa-B kinase subunit beta isoform 5 [Homo sapiens];NP_001547.1//inhibitor of nuclear factor kappa-B kinase subunit beta isoform 1 [Homo sapiens];NP_001177649.1//inhibitor of nuclear factor kappa-B kinase subunit beta isoform 2 [Homo sapiens]","1//3;2//1"]
[10961,1470,63.92,63.27,-0.0147458124131292,0.911626565327639,"*",0.855242,"ERP29","GO:0005790//smooth endoplasmic reticulum;GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005788//endoplasmic reticulum lumen;GO:0005783//endoplasmic reticulum;GO:0009986//cell surface;GO:0030133//transport vesicle;GO:0042470//melanosome","GO:0051087//chaperone binding;GO:0042803//protein homodimerization activity","GO:0006457//protein folding;GO:0050709//negative regulation of protein secretion;GO:0000187//activation of MAPK activity;GO:0010629//negative regulation of gene expression;GO:0010628//positive regulation of gene expression;GO:0043335//protein unfolding;GO:0006886//intracellular protein transport;GO:0009306//protein secretion;GO:1902235//regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway;GO:0001934//positive regulation of protein phosphorylation","K09586//endoplasmic reticulum protein 29","XP_003832503.1//PREDICTED: endoplasmic reticulum resident protein 29 isoform X1 [Pan paniscus];NP_006808.1//endoplasmic reticulum resident protein 29 isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[1635,2173,28.74,28.45,-0.0146314092633921,0.952374640845533,"*",0.908196,"DCTD","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0004132//dCMP deaminase activity;GO:0042802//identical protein binding;GO:0008270//zinc ion binding","GO:0006231//dTMP biosynthetic process;GO:0006220//pyrimidine nucleotide metabolic process;GO:0006226//dUMP biosynthetic process;GO:0015949//nucleobase-containing small molecule interconversion","K01493//dCMP deaminase [EC:3.5.4.12]","XP_517546.1//PREDICTED: deoxycytidylate deaminase isoform X2 [Pan troglodytes];XP_017404812.1//PREDICTED: deoxycytidylate deaminase isoform X1 [Cebus capucinus imitator]","1//3;2//1"]
[10749,7935,42.64,42.21,-0.014622608801487,0.796393545403271,"*",0.707152,"KIF1C","GO:0005783//endoplasmic reticulum;GO:0005874//microtubule;GO:0005794//Golgi apparatus;GO:0005871//kinesin complex","GO:0003723//RNA binding;GO:0005524//ATP binding;GO:0003774//motor activity;GO:0003777//microtubule motor activity;GO:0008017//microtubule binding;GO:0016887//ATPase activity","GO:0007018//microtubule-based movement;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0030705//cytoskeleton-dependent intracellular transport","K10392//kinesin family member 1","NP_006603.2//kinesin-like protein KIF1C [Homo sapiens]",5]
[51573,2935,39.97,39.57,-0.014510507447746,0.703183585959135,"*",0.588158,"GDE1","GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0030659//cytoplasmic vesicle membrane","GO:0004622//lysophospholipase activity;GO:0046872//metal ion binding;GO:0047395//glycerophosphoinositol glycerophosphodiesterase activity;GO:0008889//glycerophosphodiester phosphodiesterase activity","GO:0006644//phospholipid metabolic process;GO:0046475//glycerophospholipid catabolic process;GO:0070291//N-acylethanolamine metabolic process;GO:0006629//lipid metabolic process","K19179//glycerophosphoinositol glycerophosphodiesterase [EC:3.1.4.44]","NP_001310996.1//glycerophosphodiester phosphodiesterase 1 isoform 3 [Homo sapiens];NP_057725.1//glycerophosphodiester phosphodiesterase 1 isoform 1 [Homo sapiens];XP_014708948.1//PREDICTED: glycerophosphodiester phosphodiesterase 1 isoform X3 [Equus asinus]","1//3;3//A2MP1"]
[54977,2156,19.18,18.99,-0.0143628148686334,0.946044839876373,"*",0.90062,"SLC25A38","GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane","GO:0015187//glycine transmembrane transporter activity;GO:0005215//transporter activity","GO:0036233//glycine import;GO:0006839//mitochondrial transport;GO:0006783//heme biosynthetic process;GO:0030218//erythrocyte differentiation","K15118//solute carrier family 25, member 38","NP_060345.2//solute carrier family 25 member 38 isoform 1 [Homo sapiens];NP_001341727.1//solute carrier family 25 member 38 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[55650,2474,5.07,5.02,-0.0142983830525687,0.963524296596328,"*",0.923292,"PIGV","GO:0031501//mannosyltransferase complex;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0004376//glycolipid mannosyltransferase activity;GO:0000030//mannosyltransferase activity;GO:0004584//dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity","GO:0006506//GPI anchor biosynthetic process;GO:0016254//preassembly of GPI anchor in ER membrane","K07542//phosphatidylinositol glycan, class V [EC:2.4.1.-]","NP_060307.2//GPI mannosyltransferase 2 [Homo sapiens]","1//3;3//A2MP1"]
[83608,1057,10.15,10.05,-0.0142842260062476,0.997309100803317,"*",0.96372,"C18orf21","NA","NA","NA","NA","NP_001188405.1//UPF0711 protein C18orf21 isoform c [Homo sapiens];NP_113634.3//UPF0711 protein C18orf21 isoform a [Homo sapiens];AAH25950.2//C18orf21 protein, partial [Homo sapiens]","4;1//3"]
[79796,6197,4.07,4.03,-0.0142489557382796,0.845831425350564,"*",0.770324,"ALG9","GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0052918//dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity;GO:0000026//alpha-1,2-mannosyltransferase activity;GO:0016757//transferase activity, transferring glycosyl groups;GO:0052926//dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity;GO:0000030//mannosyltransferase activity","GO:0006486//protein glycosylation;GO:0006488//dolichol-linked oligosaccharide biosynthetic process","K03846//alpha-1,2-mannosyltransferase [EC:2.4.1.259 2.4.1.261]","XP_021782218.1//alpha-1,2-mannosyltransferase ALG9 isoform X7 [Papio anubis];NP_001071158.1//alpha-1,2-mannosyltransferase ALG9 isoform b [Homo sapiens];XP_014971160.1//PREDICTED: alpha-1,2-mannosyltransferase ALG9 isoform X1 [Macaca mulatta];XP_012325977.2//alpha-1,2-mannosyltransferase ALG9 isoform X4 [Aotus nancymaae];XP_008019018.1//PREDICTED: alpha-1,2-mannosyltransferase ALG9 isoform X6 [Chlorocebus sabaeus];NP_001339346.1//alpha-1,2-mannosyltransferase ALG9 isoform f [Homo sapiens];XP_012325975.1//alpha-1,2-mannosyltransferase ALG9 isoform X3 [Aotus nancymaae];NP_079016.2//alpha-1,2-mannosyltransferase ALG9 isoform a [Homo sapiens];NP_001339347.1//alpha-1,2-mannosyltransferase ALG9 isoform g [Homo sapiens];XP_016873802.1//PREDICTED: alpha-1,2-mannosyltransferase ALG9 isoform X4 [Homo sapiens];XP_005579650.1//PREDICTED: alpha-1,2-mannosyltransferase ALG9 isoform X3 [Macaca fascicularis]","1//3;2//1"]
[51107,2196,82.34,81.54,-0.0140854918327218,0.640112617654133,"*",0.49982,"APH1A","GO:0016021//integral component of membrane","NA","GO:0016485//protein processing;GO:0043085//positive regulation of catalytic activity","K06172//gamma-secretase subunit APH-1A","XP_002919359.2//PREDICTED: gamma-secretase subunit APH-1A [Ailuropoda melanoleuca];XP_004632461.1//PREDICTED: gamma-secretase subunit APH-1A isoform X4 [Octodon degus];XP_017516511.1//PREDICTED: gamma-secretase subunit APH-1A isoform X1 [Manis javanica];XP_004632460.1//PREDICTED: gamma-secretase subunit APH-1A isoform X2 [Octodon degus]","1//3;3//A2MP1;2//1"]
[54868,4763,15.48,15.33,-0.0140477744856328,0.977448353369763,"*",0.940612,"TMEM104","GO:0016021//integral component of membrane","NA","NA","K21125//mucin-5AC;K01069//hydroxyacylglutathione hydrolase [EC:3.1.2.6]","NP_001308193.1//transmembrane protein 104 isoform 2 [Homo sapiens];NP_060198.3//transmembrane protein 104 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[7484,2654,2.07,2.05,-0.0140068579938793,0.97787350962539,"*",0.941266,"WNT9B","GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix","GO:0048018//receptor ligand activity;GO:0005102//receptor binding;GO:0039706//co-receptor binding;GO:0005109//frizzled binding","GO:0009786//regulation of asymmetric cell division;GO:0009267//cellular response to starvation;GO:0072003//kidney rudiment formation;GO:0003339//regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis;GO:0001932//regulation of protein phosphorylation;GO:0030539//male genitalia development;GO:0001658//branching involved in ureteric bud morphogenesis;GO:1902455//negative regulation of stem cell population maintenance;GO:0060021//palate development;GO:0043085//positive regulation of catalytic activity;GO:0072181//mesonephric duct formation;GO:0061038//uterus morphogenesis;GO:0045165//cell fate commitment;GO:0072174//metanephric tubule formation;GO:1905438//non-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation;GO:0030182//neuron differentiation;GO:1904948//midbrain dopaminergic neuron differentiation;GO:0007267//cell-cell signaling;GO:0061303//cornea development in camera-type eye;GO:0001701//in utero embryonic development;GO:0032526//response to retinoic acid;GO:0072046//establishment of planar polarity involved in nephron morphogenesis;GO:0071300//cellular response to retinoic acid;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0060070//canonical Wnt signaling pathway;GO:0007275//multicellular organism development;GO:0016055//Wnt signaling pathway;GO:0035150//regulation of tube size;GO:0072044//collecting duct development;GO:0072038//mesenchymal stem cell maintenance involved in nephron morphogenesis","K01064//wingless-type MMTV integration site family, member 9","NP_003387.1//protein Wnt-9b isoform 1 precursor [Homo sapiens];NP_001307387.1//protein Wnt-9b isoform 2 precursor [Homo sapiens]","1//3;2//1"]
[51195,3709,4.14,4.1,-0.0140068579938793,1.00692766181135,"*",0.973708,"RAPGEFL1","GO:0005622//intracellular","GO:0005085//guanyl-nucleotide exchange factor activity","GO:0007264//small GTPase mediated signal transduction","K04351//Rap guanine nucleotide exchange factor 4","XP_014197529.1//PREDICTED: rap guanine nucleotide exchange factor-like 1 isoform X1 [Pan paniscus];NP_057423.2//rap guanine nucleotide exchange factor-like 1 isoform 3 [Homo sapiens];NP_001290463.1//rap guanine nucleotide exchange factor-like 1 isoform 2 [Homo sapiens]","1//3;2//1;5"]
[90485,2774,1.04,1.03,-0.0139391909578737,0.955352579440477,"*",0.91283,"ZNF835","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","EHH30446.1//hypothetical protein EGK_11119 [Macaca mulatta]","2//1"]
[54532,6612,2.11,2.09,-0.0137400566263024,0.968633687451083,"*",0.929704,"USP53","GO:0005911//cell-cell junction;GO:0005923//bicellular tight junction","GO:0036459//thiol-dependent ubiquitinyl hydrolase activity","GO:0010996//response to auditory stimulus;GO:0051402//neuron apoptotic process;GO:0007605//sensory perception of sound;GO:0001508//action potential;GO:0016579//protein deubiquitination","K14206//solute carrier family 15 (oligopeptide transporter), member 1","NP_061923.2//inactive ubiquitin carboxyl-terminal hydrolase 53 [Homo sapiens]","2//1"]
[445329,1397,27.69,27.43,-0.0136104315186531,0.961142713912134,"*",0.920348,"SULT1A4","GO:0005829//cytosol","GO:0004062//aryl sulfotransferase activity;GO:0008146//sulfotransferase activity;GO:0043199//sulfate binding;GO:0047685//amine sulfotransferase activity","GO:1901215//negative regulation of neuron death;GO:0006805//xenobiotic metabolic process;GO:0097720//calcineurin-mediated signaling;GO:0070371//ERK1 and ERK2 cascade;GO:0007212//dopamine receptor signaling pathway;GO:0042420//dopamine catabolic process;GO:0008202//steroid metabolic process;GO:0098989//NMDA selective glutamate receptor signaling pathway;GO:1903351//cellular response to dopamine;GO:0036498//IRE1-mediated unfolded protein response;GO:0051923//sulfation;GO:0009812//flavonoid metabolic process;GO:0006068//ethanol catabolic process;GO:0006584//catecholamine metabolic process;GO:0050427//3'-phosphoadenosine 5'-phosphosulfate metabolic process","K01014//aryl sulfotransferase [EC:2.8.2.1]","XP_005591701.1//PREDICTED: sulfotransferase 1A3 isoform X2 [Macaca fascicularis]","2//1"]
[1487,2353,52.68,52.19,-0.0134819436359957,0.740530528301887,"*",0.63882,"CTBP1","GO:0017053//transcriptional repressor complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription factor complex;GO:0005829//cytosol","GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0003714//transcription corepressor activity;GO:0042802//identical protein binding;GO:0070491//repressing transcription factor binding;GO:0051287//NAD binding;GO:0042803//protein homodimerization activity;GO:0001106//RNA polymerase II transcription corepressor activity;GO:0008022//protein C-terminus binding;GO:0019904//protein domain specific binding;GO:0008134//transcription factor binding;GO:0030267//glyoxylate reductase (NADP) activity;GO:0016618//hydroxypyruvate reductase activity;GO:0003700//DNA binding transcription factor activity","GO:0045892//negative regulation of transcription, DNA-templated;GO:0019079//viral genome replication;GO:1903758//negative regulation of transcription from RNA polymerase II promoter by histone modification;GO:0090241//negative regulation of histone H4 acetylation;GO:0050872//white fat cell differentiation;GO:0006468//protein phosphorylation;GO:0006351//transcription, DNA-templated;GO:0035067//negative regulation of histone acetylation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0031065//positive regulation of histone deacetylation;GO:0051726//regulation of cell cycle;GO:0008285//negative regulation of cell proliferation","K04496//C-terminal binding protein","NP_001012632.1//C-terminal-binding protein 1 isoform 2 [Homo sapiens];XP_008991975.1//PREDICTED: C-terminal-binding protein 1 isoform X2 [Callithrix jacchus]","1//3;2//1"]
[374659,955,41.27,40.89,-0.013345375480669,0.786925041557522,"*",0.695838,"HDDC3","NA","GO:0046872//metal ion binding;GO:0008893//guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity","NA","K21138//guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [EC:3.1.7.2]","NP_940929.1//guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 isoform 2 [Homo sapiens];NP_001273380.1//guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 isoform 1 [Homo sapiens]","1//3;4"]
[9410,1638,33.02,32.72,-0.0131673719715094,0.944261930843707,"*",0.897504,"SNRNP40","GO:0005654//nucleoplasm;GO:0005732//small nucleolar ribonucleoprotein complex;GO:0016607//nuclear speck;GO:0071013//catalytic step 2 spliceosome;GO:0005829//cytosol;GO:0030529//intracellular ribonucleoprotein complex;GO:0005682//U5 snRNP;GO:0071011//precatalytic spliceosome;GO:0019013//viral nucleocapsid","GO:0003723//RNA binding","GO:0006396//RNA processing;GO:0000398//mRNA splicing, via spliceosome;GO:0008380//RNA splicing;GO:0000375//RNA splicing, via transesterification reactions","K12857//Prp8 binding protein","XP_007977858.1//PREDICTED: U5 small nuclear ribonucleoprotein 40 kDa protein [Chlorocebus sabaeus]","2//1"]
[5468,3798,33.11,32.81,-0.0131314168785794,0.732958115555555,"*",0.629764,"PPARG","GO:0090575//RNA polymerase II transcription factor complex;GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0003707//steroid hormone receptor activity;GO:0046982//protein heterodimerization activity;GO:0043621//protein self-association;GO:0003690//double-stranded DNA binding;GO:0050544//arachidonic acid binding;GO:0050693//LBD domain binding;GO:0050692//DBD domain binding;GO:0008144//drug binding;GO:0003682//chromatin binding;GO:0043565//sequence-specific DNA binding;GO:0008270//zinc ion binding;GO:0033613//activating transcription factor binding;GO:0042802//identical protein binding;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0042277//peptide binding;GO:0044212//transcription regulatory region DNA binding;GO:0004879//nuclear receptor activity;GO:0046965//retinoid X receptor binding;GO:0008022//protein C-terminus binding;GO:0051393//alpha-actinin binding;GO:0019899//enzyme binding","GO:0008217//regulation of blood pressure;GO:0010891//negative regulation of sequestering of triglyceride;GO:0031100//animal organ regeneration;GO:0042593//glucose homeostasis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0035357//peroxisome proliferator activated receptor signaling pathway;GO:0045713//low-density lipoprotein particle receptor biosynthetic process;GO:0042953//lipoprotein transport;GO:0043388//positive regulation of DNA binding;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0045165//cell fate commitment;GO:0060336//negative regulation of interferon-gamma-mediated signaling pathway;GO:0006351//transcription, DNA-templated;GO:0032526//response to retinoic acid;GO:0048511//rhythmic process;GO:0010887//negative regulation of cholesterol storage;GO:0032869//cellular response to insulin stimulus;GO:0048469//cell maturation;GO:0010745//negative regulation of macrophage derived foam cell differentiation;GO:0010871//negative regulation of receptor biosynthetic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0010742//macrophage derived foam cell differentiation;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0030224//monocyte differentiation","K08530//peroxisome proliferator-activated receptor gamma","NP_056953.2//peroxisome proliferator-activated receptor gamma isoform 2 [Homo sapiens];AAO66458.1//CREB3L2-PPARgamma [Homo sapiens];XP_011532145.1//PREDICTED: peroxisome proliferator-activated receptor gamma isoform X3 [Homo sapiens];NP_001341598.1//peroxisome proliferator-activated receptor gamma isoform 5 [Homo sapiens];NP_001341597.1//peroxisome proliferator-activated receptor gamma isoform 4 [Homo sapiens];XP_021550891.1//peroxisome proliferator-activated receptor gamma isoform X2 [Neomonachus schauinslandi]","4;1//3;3//A2MP1;5"]
[84256,4963,8.88,8.8,-0.0130561528254464,0.893178113471363,"*",0.831784,"FLYWCH1","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding","NA","K06237//collagen, type IV, alpha","NP_001294997.1//FLYWCH-type zinc finger-containing protein 1 isoform c [Homo sapiens];NP_115672.2//FLYWCH-type zinc finger-containing protein 1 isoform a [Homo sapiens]","1//3;2//1"]
[57567,4221,8.92,8.84,-0.0129973405288732,0.961191292486759,"*",0.920214,"ZNF319","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","NP_065858.1//zinc finger protein 319 [Homo sapiens]","2//1"]
[10491,6668,68.17,67.56,-0.012967654903874,0.798438942800789,"*",0.709568,"CRTAP","GO:0032991//macromolecular complex;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum","GO:0032403//protein complex binding","GO:0018400//peptidyl-proline hydroxylation to 3-hydroxy-L-proline;GO:1901874//negative regulation of post-translational protein modification;GO:0007283//spermatogenesis;GO:0050821//protein stabilization;GO:0061077//chaperone-mediated protein folding","K19606//cartilage-associated protein","XP_008007581.1//PREDICTED: LOW QUALITY PROTEIN: cartilage-associated protein [Chlorocebus sabaeus]",4]
[10603,2045,4.51,4.47,-0.0128526020720633,0.833234560928433,"*",0.755096,"SH2B2","GO:0001726//ruffle;GO:0005884//actin filament;GO:0001725//stress fiber;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0005070//SH3/SH2 adaptor activity;GO:0042802//identical protein binding;GO:0008269//JAK pathway signal transduction adaptor activity;GO:0005068//transmembrane receptor protein tyrosine kinase adaptor activity;GO:0004871//signal transducer activity","GO:0007399//nervous system development;GO:0030036//actin cytoskeleton organization;GO:0007165//signal transduction;GO:0008286//insulin receptor signaling pathway;GO:0007596//blood coagulation;GO:0035556//intracellular signal transduction;GO:0019222//regulation of metabolic process;GO:0001922//B-1 B cell homeostasis;GO:0046578//regulation of Ras protein signal transduction;GO:0050873//brown fat cell differentiation;GO:0019221//cytokine-mediated signaling pathway;GO:0050851//antigen receptor-mediated signaling pathway","K07193//SH2B adapter protein 2","XP_005277032.1//PREDICTED: SH2B adapter protein 2 isoform X1 [Homo sapiens];XP_011514042.1//PREDICTED: SH2B adapter protein 2 isoform X3 [Homo sapiens];NP_066189.3//SH2B adapter protein 2 [Homo sapiens]","1//3;4"]
[9878,4493,25.68,25.46,-0.0124127832209451,0.975150109867222,"*",0.937912,"TOX4","GO:0000784//nuclear chromosome, telomeric region;GO:0005634//nucleus;GO:0072357//PTW/PP1 phosphatase complex;GO:0000785//chromatin","GO:0003677//DNA binding","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K09272//structure-specific recognition protein 1;K18808//toll-like receptor 13","NP_055643.1//TOX high mobility group box family member 4 isoform 1 [Homo sapiens];NP_001290452.1//TOX high mobility group box family member 4 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[26156,5137,55.44,54.97,-0.0122827780994522,0.857159296351961,"*",0.78547,"RSL1D1","GO:0016020//membrane;GO:0030686//90S preribosome;GO:0005730//nucleolus","GO:0003723//RNA binding;GO:0048027//mRNA 5'-UTR binding;GO:0003730//mRNA 3'-UTR binding;GO:0045296//cadherin binding","GO:0000470//maturation of LSU-rRNA;GO:0001649//osteoblast differentiation;GO:0032880//regulation of protein localization;GO:2000772//regulation of cellular senescence;GO:0042981//regulation of apoptotic process","K14775//ribosome biogenesis protein UTP30","AAH19069.2//RSL1D1 protein, partial [Homo sapiens]","2//1"]
[283237,1130,15.36,15.23,-0.0122622742338639,0.884808328611898,"*",0.82122,"TTC9C","NA","NA","NA","K09571//FK506-binding protein 4/5 [EC:5.2.1.8];K09572//FK506-binding protein 6 [EC:5.2.1.8];K05864//peptidyl-prolyl isomerase D [EC:5.2.1.8]","EAW74086.1//tetratricopeptide repeat domain 9C, isoform CRA_a [Homo sapiens];AAL55789.1//unknown [Homo sapiens]","1//3;3//A2MP1"]
[84969,2464,7.13,7.07,-0.0121918616344892,0.94707440973044,"*",0.901778,"TOX2","GO:0005654//nucleoplasm","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0045944//positive regulation of transcription from RNA polymerase II promoter","K10955//mucin-2;K10802//high mobility group protein B1;K09272//structure-specific recognition protein 1;K18808//toll-like receptor 13","NP_001092267.1//TOX high mobility group box family member 2 isoform a [Homo sapiens];NP_001092268.1//TOX high mobility group box family member 2 isoform b [Homo sapiens]","1//3;2//1"]
[10482,2856,26.22,26,-0.0121560623059377,0.463547340484557,"*",0.31381,"NXF1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005643//nuclear pore;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0005737//cytoplasm;GO:0042405//nuclear inclusion body;GO:0000346//transcription export complex","GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005487//nucleocytoplasmic transporter activity;GO:0003727//single-stranded RNA binding","GO:0016973//poly(A)+ mRNA export from nucleus;GO:0006406//mRNA export from nucleus;GO:0016032//viral process;GO:0006405//RNA export from nucleus","K14284//nuclear RNA export factor","XP_020031017.1//nuclear RNA export factor 1 [Castor canadensis];Q5R752.1//RecName: Full=Nuclear RNA export factor 1","4;1//3"]
[30011,4187,28.67,28.43,-0.0121278055629963,0.580711069296741,"*",0.423882,"SH3KBP1","GO:0005856//cytoskeleton;GO:0005925//focal adhesion;GO:0005737//cytoplasm;GO:0043005//neuron projection;GO:0030139//endocytic vesicle;GO:0005911//cell-cell junction;GO:0005829//cytosol;GO:0045202//synapse;GO:0005886//plasma membrane;GO:0030659//cytoplasmic vesicle membrane","GO:0016301//kinase activity;GO:0017124//SH3 domain binding","GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0016477//cell migration;GO:0007267//cell-cell signaling;GO:0008360//regulation of cell shape;GO:0061024//membrane organization;GO:0006915//apoptotic process;GO:0007010//cytoskeleton organization;GO:0006897//endocytosis;GO:0007411//axon guidance","K12470//SH3 domain-containing kinase-binding protein 1","NP_001340820.1//SH3 domain-containing kinase-binding protein 1 isoform e [Homo sapiens];NP_001171889.1//SH3 domain-containing kinase-binding protein 1 isoform c [Homo sapiens];NP_001340826.1//SH3 domain-containing kinase-binding protein 1 isoform j [Homo sapiens];NP_001340819.1//SH3 domain-containing kinase-binding protein 1 isoform d [Homo sapiens];XP_011543802.1//PREDICTED: SH3 domain-containing kinase-binding protein 1 isoform X6 [Homo sapiens];NP_114098.1//SH3 domain-containing kinase-binding protein 1 isoform a [Homo sapiens];NP_001340821.1//SH3 domain-containing kinase-binding protein 1 isoform f [Homo sapiens];NP_001019837.1//SH3 domain-containing kinase-binding protein 1 isoform b [Homo sapiens]","1//3;2//1"]
[144363,1149,8.4,8.33,-0.0120728323005751,0.99388946270011,"*",0.95998,"ETFRF1","GO:0005739//mitochondrion","NA","GO:0022904//respiratory electron transport chain","K00560//thymidylate synthase [EC:2.1.1.45];K20301//trafficking protein particle complex subunit 2;K11846//ubiquitin carboxyl-terminal hydrolase 18/41 [EC:3.4.19.12]","NP_001001660.2//electron transfer flavoprotein regulatory factor 1 [Homo sapiens]","2//1"]
[902,1415,26.43,26.21,-0.0120590713131523,0.979829302234927,"*",0.94413,"CCNH","GO:0005675//holo TFIIH complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0070985//TFIIK complex;GO:0019907//cyclin-dependent protein kinase activating kinase holoenzyme complex","GO:0008353//RNA polymerase II carboxy-terminal domain kinase activity;GO:0016301//kinase activity;GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity;GO:0008094//DNA-dependent ATPase activity","GO:0006361//transcription initiation from RNA polymerase I promoter;GO:0006370//7-methylguanosine mRNA capping;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0006362//transcription elongation from RNA polymerase I promoter;GO:0006363//termination of RNA polymerase I transcription;GO:1901409//positive regulation of phosphorylation of RNA polymerase II C-terminal domain;GO:0006468//protein phosphorylation;GO:0006351//transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter;GO:0006294//nucleotide-excision repair, preincision complex assembly;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0000082//G1/S transition of mitotic cell cycle;GO:0000086//G2/M transition of mitotic cell cycle;GO:0050821//protein stabilization;GO:0006367//transcription initiation from RNA polymerase II promoter","K06634//cyclin H","NP_001230.1//cyclin-H isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[57666,4563,20.73,20.56,-0.0118798519155368,0.927185231320504,"*",0.874714,"FBRSL1","NA","GO:0003723//RNA binding","NA","K16628//collagen, type VII, alpha","NP_001136113.1//fibrosin-1-like protein [Homo sapiens]","1//3"]
[5713,1686,70.9,70.32,-0.0118505569834746,0.920787227729359,"*",0.86643,"PSMD7","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005654//nucleoplasm;GO:0005838//proteasome regulatory particle","GO:0042803//protein homodimerization activity","NA","K03038//26S proteasome regulatory subunit N8","XP_008516632.1//PREDICTED: 26S proteasome non-ATPase regulatory subunit 7 [Equus przewalskii]",4]
[56906,2119,4.96,4.92,-0.0116818050476353,0.996956031877673,"*",0.963254,"THAP10","NA","GO:0046872//metal ion binding;GO:0003677//DNA binding","NA","K09228//KRAB domain-containing zinc finger protein;K09291//nucleoprotein TPR","NP_064532.1//THAP domain-containing protein 10 [Homo sapiens]","3//A2MP1"]
[3892,2256,41.5,41.17,-0.0115178878003801,0.937927775942929,"*",0.8889,"KRT86","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0045095//keratin filament","GO:0005198//structural molecule activity","GO:0031424//keratinization;GO:0070268//cornification","K07605//type II keratin, basic","XP_005268923.1//PREDICTED: keratin, type II cuticular Hb6 isoform X1 [Homo sapiens]","1//3"]
[51559,7214,6.36,6.31,-0.0113867603018066,0.971004311542723,"*",0.932648,"NT5DC3","GO:0043235//receptor complex","GO:0046872//metal ion binding;GO:0008253//5'-nucleotidase activity","NA","K01081//5'-nucleotidase [EC:3.1.3.5]","NP_001026871.1//5'-nucleotidase domain-containing protein 3 [Homo sapiens]","2//1"]
[10641,1672,11.48,11.39,-0.0113548949675759,0.97949786302794,"*",0.943688,"NPRL2","GO:0005765//lysosomal membrane;GO:1990130//GATOR1 complex","GO:0004672//protein kinase activity;GO:0005096//GTPase activator activity","GO:0032007//negative regulation of TOR signaling;GO:0034198//cellular response to amino acid starvation;GO:0033673//negative regulation of kinase activity","K20405//nitrogen permease regulator 2-like protein","XP_002813758.1//PREDICTED: nitrogen permease regulator 2-like protein [Pongo abelii]",4]
[138716,936,35.81,35.53,-0.0113248299893024,0.94208692023731,"*",0.89467,"RPP25L","NA","NA","NA","K14525//ribonucleases P/MRP protein subunit RPP25 [EC:3.1.26.5]","XP_003911616.2//ribonuclease P protein subunit p25-like protein isoform X1 [Papio anubis];XP_017747535.1//PREDICTED: ribonuclease P protein subunit p25-like protein isoform X1 [Rhinopithecus bieti]","2//1"]
[51385,3399,2.57,2.55,-0.0112711123350201,0.99174246596655,"*",0.95772,"ZNF589","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_009443668.1//PREDICTED: zinc finger protein 589 isoform X2 [Pan troglodytes]","2//1"]
[25983,1161,28.31,28.09,-0.0112551247793487,0.953554747572815,"*",0.909978,"NGDN","GO:0030425//dendrite;GO:0030424//axon;GO:0005634//nucleus;GO:0000775//chromosome, centromeric region;GO:0030175//filopodium;GO:0005730//nucleolus;GO:0032040//small-subunit processome;GO:0005739//mitochondrion","GO:0003723//RNA binding","GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006417//regulation of translation","K14765//U3 small nucleolar ribonucleoprotein protein LCP5","NP_001036100.1//neuroguidin isoform 1 [Homo sapiens];NP_056329.1//neuroguidin isoform 2 [Homo sapiens]","1//3"]
[10201,3079,5.15,5.11,-0.0112491411329594,1.0077461445674,"*",0.974878,"NME6","GO:0005829//cytosol;GO:0005739//mitochondrion","GO:0046872//metal ion binding;GO:0005524//ATP binding;GO:0004550//nucleoside diphosphate kinase activity","GO:0006228//UTP biosynthetic process;GO:0030308//negative regulation of cell growth;GO:0006241//CTP biosynthetic process;GO:0045839//negative regulation of mitotic nuclear division;GO:0015949//nucleobase-containing small molecule interconversion;GO:0006183//GTP biosynthetic process;GO:0006915//apoptotic process","K00940//nucleoside-diphosphate kinase [EC:2.7.4.6]","NP_005784.1//nucleoside diphosphate kinase 6 isoform 1 [Homo sapiens];XP_016861001.1//PREDICTED: nucleoside diphosphate kinase 6 isoform X2 [Homo sapiens];XP_016796506.1//PREDICTED: nucleoside diphosphate kinase 6 isoform X2 [Pan troglodytes];NP_001295359.1//nucleoside diphosphate kinase 6 isoform 3 [Homo sapiens];XP_009199120.1//nucleoside diphosphate kinase 6 isoform X1 [Papio anubis];XP_016796505.1//PREDICTED: nucleoside diphosphate kinase 6 isoform X1 [Pan troglodytes]","1//3;4"]
[22806,9045,2.59,2.57,-0.0111837384926758,0.912307326576877,"*",0.856566,"IKZF3","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity;GO:0044212//transcription regulatory region DNA binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0030888//regulation of B cell proliferation;GO:0007498//mesoderm development;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0045577//regulation of B cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0042981//regulation of apoptotic process;GO:0042113//B cell activation;GO:0045619//regulation of lymphocyte differentiation","K09228//KRAB domain-containing zinc finger protein;K09220//IKAROS family zinc finger protein","XP_006155969.1//PREDICTED: zinc finger protein Aiolos isoform X2 [Tupaia chinensis];NP_001244342.1//zinc finger protein Aiolos isoform 12 [Homo sapiens];NP_001244340.1//zinc finger protein Aiolos isoform 10 [Homo sapiens];XP_004041875.2//PREDICTED: zinc finger protein Aiolos isoform X3 [Gorilla gorilla gorilla];XP_004434617.2//PREDICTED: LOW QUALITY PROTEIN: zinc finger protein Aiolos [Ceratotherium simum simum];NP_899051.1//zinc finger protein Aiolos isoform 2 [Homo sapiens];NP_899052.1//zinc finger protein Aiolos isoform 3 [Homo sapiens];NP_899054.1//zinc finger protein Aiolos isoform 5 [Homo sapiens];XP_011592380.1//PREDICTED: zinc finger protein Aiolos [Aquila chrysaetos canadensis];CAC80428.1//AIOLOS isoform three [Homo sapiens];NP_001244341.1//zinc finger protein Aiolos isoform 11 [Homo sapiens];XP_004591209.1//PREDICTED: zinc finger protein Aiolos isoform X2 [Ochotona princeps];NP_001244343.1//zinc finger protein Aiolos isoform 13 [Homo sapiens];ELK01560.1//Zinc finger protein Aiolos [Pteropus alecto]","4;1//3;2//1"]
[6522,4036,148.26,147.12,-0.0111360316380027,0.637280216500425,"*",0.51596,"SLC4A2","GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005925//focal adhesion;GO:0016324//apical plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0015301//anion:anion antiporter activity;GO:0008510//sodium:bicarbonate symporter activity;GO:0005452//inorganic anion exchanger activity;GO:0019899//enzyme binding;GO:0008509//anion transmembrane transporter activity","GO:0015701//bicarbonate transport;GO:0006820//anion transport;GO:0051453//regulation of intracellular pH;GO:0007283//spermatogenesis;GO:0048565//digestive tract development","K13855//solute carrier family 4 (anion exchanger), member 2","BAD92395.1//Anion exchanger 2 type a variant, partial [Homo sapiens];NP_001186622.1//anion exchange protein 2 isoform 2 [Homo sapiens];NP_001186623.1//anion exchange protein 2 isoform 3 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[51234,1031,78.27,77.67,-0.0111019789173408,0.939678562302006,"*",0.891324,"EMC4","GO:0072546//ER membrane protein complex;GO:0016021//integral component of membrane","NA","GO:0034975//protein folding in endoplasmic reticulum;GO:0006915//apoptotic process","K18203//[phosphatase 2A protein]-leucine-carboxy methyltransferase [EC:2.1.1.233]","NP_001273349.1//ER membrane protein complex subunit 4 isoform b [Homo sapiens];XP_006234766.1//PREDICTED: ER membrane protein complex subunit 4 isoform X2 [Rattus norvegicus];NP_057538.1//ER membrane protein complex subunit 4 isoform a [Homo sapiens]","1//3;3//A2MP1"]
[5859,2843,37.9,37.61,-0.0110815420181477,0.936708261852807,"*",0.886806,"QARS","GO:0005829//cytosol;GO:0017101//aminoacyl-tRNA synthetase multienzyme complex","GO:0004860//protein kinase inhibitor activity;GO:0005524//ATP binding;GO:0004819//glutamine-tRNA ligase activity;GO:0019901//protein kinase binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0007420//brain development;GO:0032873//negative regulation of stress-activated MAPK cascade;GO:2001234//negative regulation of apoptotic signaling pathway;GO:0006425//glutaminyl-tRNA aminoacylation","K01886//glutaminyl-tRNA synthetase [EC:6.1.1.18]","EAW64954.1//glutaminyl-tRNA synthetase, isoform CRA_b [Homo sapiens]","1//3;2//1"]
[1497,4431,13.22,13.12,-0.0109544568896081,0.98142720337772,"*",0.945854,"CTNS","NA","NA","NA","K12386//cystinosin","XP_008567055.1//PREDICTED: cystinosin isoform X2 [Galeopterus variegatus];XP_015361418.1//PREDICTED: cystinosin isoform X3 [Marmota marmota marmota]","2//1"]
[116113,5946,18.58,18.44,-0.0109118459533147,0.938841203803989,"*",0.889942,"FOXP4","GO:0005634//nucleus","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0009653//anatomical structure morphogenesis;GO:0030154//cell differentiation;GO:0006351//transcription, DNA-templated","K09409//forkhead box protein P","NP_001012426.1//forkhead box protein P4 isoform 1 [Homo sapiens];NP_612466.1//forkhead box protein P4 isoform 2 [Homo sapiens];NP_001012427.1//forkhead box protein P4 isoform 3 [Homo sapiens]","1//3;2//1"]
[29775,3912,8.01,7.95,-0.0108473822369923,0.974001103457256,"*",0.936502,"CARD10","GO:0032449//CBM complex;GO:0005737//cytoplasm","GO:0030159//receptor signaling complex scaffold activity","GO:0007250//activation of NF-kappaB-inducing kinase activity;GO:0042981//regulation of apoptotic process;GO:0006461//protein complex assembly","K20912//caspase recruitment domain-containing protein 10","NP_055365.2//caspase recruitment domain-containing protein 10 [Homo sapiens]","3//A2MP1"]
[149466,1429,1.34,1.33,-0.0108067549565829,0.939272043567232,"*",0.890762,"C1orf210","GO:0016021//integral component of membrane;GO:0055037//recycling endosome;GO:0005886//plasma membrane;GO:0005769//early endosome","NA","NA","K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K02927//large subunit ribosomal protein L40e;K17985//activating molecule in BECN1-regulated autophagy protein 1","NP_872323.1//type III endosome membrane protein TEMP [Homo sapiens]","1//3;2//1"]
[50488,5030,45.62,45.28,-0.010792488480255,0.899166756068124,"*",0.8395,"MINK1","GO:0070062//extracellular exosome;GO:0030425//dendrite;GO:0030424//axon;GO:0030054//cell junction;GO:0014069//postsynaptic density;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0045211//postsynaptic membrane","GO:0004674//protein serine/threonine kinase activity;GO:0008349//MAP kinase kinase kinase kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity","GO:0046330//positive regulation of JNK cascade;GO:0001952//regulation of cell-matrix adhesion;GO:0007346//regulation of mitotic cell cycle;GO:0006950//response to stress;GO:0035556//intracellular signal transduction;GO:0030334//regulation of cell migration;GO:0048812//neuron projection morphogenesis;GO:0031098//stress-activated protein kinase signaling cascade;GO:0022407//regulation of cell-cell adhesion;GO:0031532//actin cytoskeleton reorganization;GO:0006468//protein phosphorylation;GO:2000311//regulation of AMPA receptor activity;GO:0048813//dendrite morphogenesis;GO:0007254//JNK cascade;GO:0046777//protein autophosphorylation;GO:0007275//multicellular organism development;GO:0007268//chemical synaptic transmission;GO:0042981//regulation of apoptotic process","K04413//misshapen/NIK-related kinase [EC:2.7.11.1]","NP_001020108.1//misshapen-like kinase 1 isoform 4 [Homo sapiens];NP_733763.1//misshapen-like kinase 1 isoform 2 [Homo sapiens];NP_056531.1//misshapen-like kinase 1 isoform 1 [Homo sapiens];NP_722549.2//misshapen-like kinase 1 isoform 3 [Homo sapiens]","1//3;4;3//A2MP1"]
[23404,1976,29.72,29.5,-0.0107191614020302,0.950011085556578,"*",0.90505,"EXOSC2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000176//nuclear exosome (RNase complex);GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0000177//cytoplasmic exosome (RNase complex);GO:0005829//cytosol;GO:0000178//exosome (RNase complex)","GO:0003723//RNA binding;GO:0000175//3'-5'-exoribonuclease activity;GO:0008312//7S RNA binding","GO:0043928//exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay;GO:0034427//nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5';GO:0030307//positive regulation of cell growth;GO:0071034//CUT catabolic process;GO:0006364//rRNA processing;GO:0071049//nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription;GO:0000467//exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0071035//nuclear polyadenylation-dependent rRNA catabolic process;GO:0043488//regulation of mRNA stability;GO:0071051//polyadenylation-dependent snoRNA 3'-end processing;GO:0034475//U4 snRNA 3'-end processing;GO:0071038//nuclear polyadenylation-dependent tRNA catabolic process","K03679//exosome complex component RRP4","NP_001269638.1//exosome complex component RRP4 isoform 3 [Homo sapiens];NP_001269637.1//exosome complex component RRP4 isoform 2 [Homo sapiens];OWK10071.1//EXOSC2, partial [Cervus elaphus hippelaphus]","6;1//3"]
[84305,1170,20.54,20.39,-0.0105744063015984,0.883046776066991,"*",0.81859,"PYM1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0035145//exon-exon junction complex;GO:0030054//cell junction","GO:0043022//ribosome binding;GO:0003723//RNA binding","GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0045727//positive regulation of translation;GO:1903259//exon-exon junction complex disassembly","K14294//partner of Y14 and mago","NP_115721.1//partner of Y14 and mago isoform 1 [Homo sapiens];NP_001137325.1//partner of Y14 and mago isoform 2 [Homo sapiens]","1//3;2//1"]
[11154,3725,9.6,9.53,-0.0105581916985767,0.686324514881402,"*",0.568772,"AP4S1","GO:0032588//trans-Golgi network membrane;GO:0030124//AP-4 adaptor complex;GO:0005905//clathrin-coated pit;GO:0031904//endosome lumen","GO:0008565//protein transporter activity","GO:0006605//protein targeting","K12403//AP-4 complex subunit sigma-1","NP_001241655.1//AP-4 complex subunit sigma-1 isoform 3 [Homo sapiens];NP_001241656.1//AP-4 complex subunit sigma-1 isoform 4 [Homo sapiens];NP_009008.2//AP-4 complex subunit sigma-1 isoform 1 [Homo sapiens];XP_002718171.2//PREDICTED: AP-4 complex subunit sigma-1 isoform X2 [Oryctolagus cuniculus]","4;1//3;2//1"]
[10645,4491,12.5,12.41,-0.0104249794190927,0.778821904584794,"*",0.681652,"CAMKK2","GO:0005634//nucleus;GO:0042995//cell projection;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005737//cytoplasm","GO:0004713//protein tyrosine kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0004683//calmodulin-dependent protein kinase activity;GO:0005509//calcium ion binding;GO:0005516//calmodulin binding","GO:0045859//regulation of protein kinase activity;GO:0000165//MAPK cascade;GO:0034614//cellular response to reactive oxygen species;GO:0061762//CAMKK-AMPK signaling cascade;GO:0006468//protein phosphorylation;GO:1903599//positive regulation of autophagy of mitochondrion;GO:0019722//calcium-mediated signaling;GO:0046777//protein autophosphorylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0018107//peptidyl-threonine phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0001934//positive regulation of protein phosphorylation;GO:0045860//positive regulation of protein kinase activity","K07359//calcium/calmodulin-dependent protein kinase kinase 2 [EC:2.7.11.17]","NP_757365.1//calcium/calmodulin-dependent protein kinase kinase 2 isoform 3 [Homo sapiens];NP_705719.2//calcium/calmodulin-dependent protein kinase kinase 2 isoform 2 [Homo sapiens];NP_705720.1//calcium/calmodulin-dependent protein kinase kinase 2 isoform 4 [Homo sapiens];NP_757364.1//calcium/calmodulin-dependent protein kinase kinase 2 isoform 6 [Homo sapiens];XP_011803910.1//PREDICTED: calcium/calmodulin-dependent protein kinase kinase 2 isoform X1 [Colobus angolensis palliatus];NP_001257415.1//calcium/calmodulin-dependent protein kinase kinase 2 isoform 7 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[57026,2072,17,16.88,-0.010219842317879,0.978505396449704,"*",0.942058,"PDXP","GO:0070062//extracellular exosome;GO:0005856//cytoskeleton;GO:0032587//ruffle membrane;GO:0030027//lamellipodium;GO:0030496//midbody;GO:0031258//lamellipodium membrane;GO:0032154//cleavage furrow;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0070938//contractile ring","GO:0000287//magnesium ion binding;GO:0033883//pyridoxal phosphatase activity;GO:0004647//phosphoserine phosphatase activity;GO:0004721//phosphoprotein phosphatase activity;GO:0031072//heat shock protein binding;GO:0016791//phosphatase activity;GO:0098519//nucleotide phosphatase activity, acting on free nucleotides","GO:0032361//pyridoxal phosphate catabolic process;GO:0030836//positive regulation of actin filament depolymerization;GO:0071318//cellular response to ATP;GO:0006470//protein dephosphorylation;GO:0032465//regulation of cytokinesis;GO:0031247//actin rod assembly;GO:0007088//regulation of mitotic nuclear division","K07758//pyridoxal phosphatase [EC:3.1.3.74]","XP_003905563.2//pyridoxal phosphate phosphatase isoform X6 [Papio anubis]",4]
[29920,1630,59.63,59.21,-0.0101974830015464,1.02107637937456,"*",0.995444,"PYCR2","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0004735//pyrroline-5-carboxylate reductase activity","GO:0006561//proline biosynthetic process;GO:0055129//L-proline biosynthetic process;GO:0008652//cellular amino acid biosynthetic process;GO:0034599//cellular response to oxidative stress","K00286//pyrroline-5-carboxylate reductase [EC:1.5.1.2]","NP_037460.2//pyrroline-5-carboxylate reductase 2 isoform 1 [Homo sapiens];NP_001258610.1//pyrroline-5-carboxylate reductase 2 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[84650,978,37.09,36.83,-0.0101488706032719,0.978441774512354,"*",0.942058,"EBPL","GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0047750//cholestenol delta-isomerase activity","GO:0016125//sterol metabolic process","K11494//RCC1 and BTB domain-containing protein;K01824//cholestenol Delta-isomerase [EC:5.3.3.5]","NP_115954.1//emopamil-binding protein-like isoform 1 [Homo sapiens];NP_001265565.1//emopamil-binding protein-like isoform 2 [Homo sapiens]","1//3;4"]
[81618,2052,51.95,51.59,-0.0100323026389003,0.854030659282051,"*",0.781908,"ITM2C","GO:0005765//lysosomal membrane;GO:0070062//extracellular exosome;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005764//lysosome;GO:0005886//plasma membrane;GO:0048471//perinuclear region of cytoplasm","GO:0001540//amyloid-beta binding;GO:0005524//ATP binding","GO:0007399//nervous system development;GO:0030182//neuron differentiation;GO:0010977//negative regulation of neuron projection development;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:0042985//negative regulation of amyloid precursor protein biosynthetic process","K18265//integral membrane protein 2C","NP_001012532.1//integral membrane protein 2C isoform 3 [Homo sapiens];XP_001112946.2//PREDICTED: integral membrane protein 2C [Macaca mulatta]","1//3;2//1;5"]
[619208,2671,1.45,1.44,-0.00998408857262213,1.02192614620939,"*",0.99237,"FAM229B","NA","NA","NA","K01368//cathepsin S [EC:3.4.22.27];K10391//tubulin epsilon;K01064//wingless-type MMTV integration site family, member 9","NP_001028736.1//protein FAM229B [Homo sapiens]","2//1"]
[90139,4242,1.49,1.48,-0.00971515483321178,0.982071147272727,"*",0.946782,"TSPAN18","GO:0016021//integral component of membrane","NA","NA","K17353//tetraspanin-18","XP_009458554.1//PREDICTED: tetraspanin-18 isoform X1 [Pan troglodytes]",4]
[4291,2257,2.99,2.97,-0.00968255339733939,0.983381750519211,"*",0.948538,"MLF1","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0019904//protein domain specific binding","GO:0002318//myeloid progenitor cell differentiation;GO:0006351//transcription, DNA-templated;GO:0007050//cell cycle arrest","K15622//myeloid leukemia factor 1","NP_001182362.1//myeloid leukemia factor 1 isoform 4 [Homo sapiens];NP_071888.1//myeloid leukemia factor 1 isoform 1 [Homo sapiens];XP_005247536.1//PREDICTED: myeloid leukemia factor 1 isoform X1 [Homo sapiens];NP_001182361.1//myeloid leukemia factor 1 isoform 3 [Homo sapiens]","4;1//3;2//1"]
[64897,2793,13.58,13.49,-0.0095931312964642,0.961219812250768,"*",0.920482,"C12orf43","NA","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K04613//vomeronasal 2 receptor;K01064//wingless-type MMTV integration site family, member 9","NP_001273121.1//uncharacterized protein C12orf43 isoform b [Homo sapiens];NP_001273125.1//uncharacterized protein C12orf43 isoform e [Homo sapiens];NP_001273127.1//uncharacterized protein C12orf43 isoform g [Homo sapiens];NP_001273120.1//uncharacterized protein C12orf43 isoform a [Homo sapiens];NP_075046.1//uncharacterized protein C12orf43 isoform c [Homo sapiens];NP_001273124.1//uncharacterized protein C12orf43 isoform d [Homo sapiens];NP_001273126.1//uncharacterized protein C12orf43 isoform f [Homo sapiens]","1//3;2//1"]
[5828,4388,4.55,4.52,-0.00954377267087103,1.01389612620418,"*",0.981716,"PEX2","GO:0005779//integral component of peroxisomal membrane;GO:0016593//Cdc73/Paf1 complex","GO:0046872//metal ion binding","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0000038//very long-chain fatty acid metabolic process;GO:0006635//fatty acid beta-oxidation;GO:0016558//protein import into peroxisome matrix;GO:0050680//negative regulation of epithelial cell proliferation;GO:0031648//protein destabilization;GO:0048147//negative regulation of fibroblast proliferation","K06664//peroxin-2","XP_005563640.1//PREDICTED: peroxisome biogenesis factor 2 [Macaca fascicularis]","1//3;2//1"]
[112849,1877,17.17,17.06,-0.00927239268384427,0.814985600947471,"*",0.732334,"L3HYPDH","NA","GO:0016836//hydro-lyase activity;GO:0050346//trans-L-3-hydroxyproline dehydratase activity","GO:0008152//metabolic process","K18384//trans-L-3-hydroxyproline dehydratase [EC:4.2.1.77]","AAH12131.1//Chromosome 14 open reading frame 149 [Homo sapiens];NP_653182.1//trans-3-hydroxy-L-proline dehydratase isoform a [Homo sapiens];NP_001318093.1//trans-3-hydroxy-L-proline dehydratase isoform c [Homo sapiens];XP_004738925.1//PREDICTED: trans-3-hydroxy-L-proline dehydratase [Mustela putorius furo]","1//3"]
[55315,2277,10.93,10.86,-0.0092692978675432,0.989321271524896,"*",0.955258,"SLC29A3","GO:0005765//lysosomal membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005794//Golgi apparatus;GO:0031902//late endosome membrane;GO:0016021//integral component of membrane","GO:0005337//nucleoside transmembrane transporter activity","NA","K15014//solute carrier family 29 (equilibrative nucleoside transporter), member 1/2/3","NP_060814.4//equilibrative nucleoside transporter 3 isoform a [Homo sapiens]","1//3;5"]
[55766,3699,10.96,10.89,-0.00924384424361993,0.984178306993642,"*",0.949676,"H2AFJ","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0000786//nucleosome","GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity","GO:0006342//chromatin silencing","K11251//histone H2A","NP_808760.1//histone H2A.J [Homo sapiens]","3//A2MP1"]
[10162,2297,36.03,35.8,-0.00923906427517164,0.955020963103742,"*",0.912274,"LPCAT3","GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0047144//2-acylglycerol-3-phosphate O-acyltransferase activity;GO:0047184//1-acylglycerophosphocholine O-acyltransferase activity;GO:0003841//1-acylglycerol-3-phosphate O-acyltransferase activity","GO:0097006//regulation of plasma lipoprotein particle levels;GO:0008654//phospholipid biosynthetic process;GO:0036152//phosphatidylethanolamine acyl-chain remodeling;GO:0036150//phosphatidylserine acyl-chain remodeling;GO:0036151//phosphatidylcholine acyl-chain remodeling","K13515//lysophospholipid acyltransferase 5 [EC:2.3.1.23 2.3.1.-]","NP_005759.4//lysophospholipid acyltransferase 5 [Homo sapiens]",5]
[6794,3286,15.9,15.8,-0.00910220710725244,0.976897042878522,"*",0.939898,"STK11","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005737//cytoplasm;GO:0036398//TCR signalosome","GO:0000287//magnesium ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0002039//p53 binding;GO:0030295//protein kinase activator activity;GO:0030275//LRR domain binding","GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0051896//regulation of protein kinase B signaling;GO:1904262//negative regulation of TORC1 signaling;GO:0042593//glucose homeostasis;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0006914//autophagy;GO:0048814//regulation of dendrite morphogenesis;GO:0008285//negative regulation of cell proliferation;GO:0071493//cellular response to UV-B;GO:0001558//regulation of cell growth;GO:0097484//dendrite extension;GO:0030154//cell differentiation;GO:0006468//protein phosphorylation;GO:0032147//activation of protein kinase activity;GO:0050772//positive regulation of axonogenesis;GO:0046777//protein autophosphorylation;GO:0007409//axonogenesis;GO:1901796//regulation of signal transduction by p53 class mediator;GO:0018107//peptidyl-threonine phosphorylation;GO:0030010//establishment of cell polarity;GO:0060070//canonical Wnt signaling pathway;GO:0018105//peptidyl-serine phosphorylation;GO:0060770//negative regulation of epithelial cell proliferation involved in prostate gland development;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:0007399//nervous system development;GO:0051055//negative regulation of lipid biosynthetic process;GO:0043276//anoikis;GO:0007283//spermatogenesis;GO:0007050//cell cycle arrest;GO:0001944//vasculature development;GO:0006974//cellular response to DNA damage stimulus;GO:0030308//negative regulation of cell growth;GO:1900182//positive regulation of protein localization to nucleus;GO:0010212//response to ionizing radiation;GO:0050852//T cell receptor signaling pathway;GO:0030111//regulation of Wnt signaling pathway;GO:0010508//positive regulation of autophagy;GO:0001894//tissue homeostasis;GO:0036399//TCR signalosome assembly;GO:0051645//Golgi localization;GO:0045059//positive thymic T cell selection;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway","K07298//serine/threonine-protein kinase 11 [EC:2.7.11.1]","NP_000446.1//serine/threonine-protein kinase STK11 [Homo sapiens]",4]
[92002,1311,21.15,21.02,-8.89499404513369E-3,0.944518748387097,"*",0.898162,"CCNQ","GO:0005634//nucleus;GO:0000307//cyclin-dependent protein kinase holoenzyme complex","GO:0030295//protein kinase activator activity;GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity","GO:1901409//positive regulation of phosphorylation of RNA polymerase II C-terminal domain;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0043410//positive regulation of MAPK cascade;GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity","K15188//cyclin T;K16667//receptor-type tyrosine-protein phosphatase gamma [EC:3.1.3.48];K21768//tubulin-specific chaperone E;K02333//DNA polymerase gamma 2","XP_011845984.1//PREDICTED: cyclin-related protein FAM58A-like [Mandrillus leucophaeus];EHH50685.1//hypothetical protein EGM_01551 [Macaca fascicularis]","4;2//1"]
[4218,2194,49.11,48.81,-0.00884007080162558,0.958657461352183,"*",0.916948,"RAB8A","NA","NA","NA","K07901//Ras-related protein Rab-8A","XP_012613861.1//ras-related protein Rab-8A [Microcebus murinus]",4]
[89953,2403,3.34,3.32,-0.00866486112712754,0.988672837969267,"*",0.95457,"KLC4","GO:0005874//microtubule;GO:0005737//cytoplasm;GO:0005871//kinesin complex","GO:0003777//microtubule motor activity","NA","K10407//kinesin light chain","NP_612352.1//kinesin light chain 4 isoform c [Homo sapiens];NP_001275964.1//kinesin light chain 4 isoform d [Homo sapiens];NP_958931.1//kinesin light chain 4 isoform b [Homo sapiens]","1//3;3//A2MP1;2//1"]
[9844,5539,1.67,1.66,-0.00866486112712721,0.535875501054111,"*",0.381896,"ELMO1","GO:0016020//membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0032045//guanyl-nucleotide exchange factor complex","GO:0005085//guanyl-nucleotide exchange factor activity;GO:0017124//SH3 domain binding","GO:0006911//phagocytosis, engulfment;GO:0016477//cell migration;GO:0030036//actin cytoskeleton organization;GO:0050690//regulation of defense response to virus by virus;GO:0006915//apoptotic process;GO:0016601//Rac protein signal transduction;GO:0065009//regulation of molecular function;GO:0048870//cell motility;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0006909//phagocytosis","K12366//engulfment and cell motility protein 1","XP_006201961.2//PREDICTED: engulfment and cell motility protein 1 isoform X1 [Vicugna pacos];EDL32677.1//engulfment and cell motility 1, ced-12 homolog (C. elegans), isoform CRA_a, partial [Mus musculus];XP_015092799.1//PREDICTED: engulfment and cell motility protein 1 isoform X3 [Vicugna pacos];XP_007979785.1//PREDICTED: engulfment and cell motility protein 1 isoform X2 [Chlorocebus sabaeus]","1//3;3//A2MP1;10//2;2//1"]
[29893,1456,18.64,18.53,-0.00853897862701444,1.01259247994825,"*",0.98001,"PSMC3IP","GO:0005654//nucleoplasm","GO:0003677//DNA binding;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity","GO:0007131//reciprocal meiotic recombination","K06695//26S proteasome regulatory subunit, ATPase 3, interacting protein","EAW60849.1//PSMC3 interacting protein, isoform CRA_c [Homo sapiens];EAW60846.1//PSMC3 interacting protein, isoform CRA_a [Homo sapiens]","6;1//3;3//A2MP1"]
[5202,668,44.41,44.15,-0.00847113343128436,0.994069370317563,"*",0.960216,"PFDN2","GO:0016272//prefoldin complex;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005737//cytoplasm","GO:0051082//unfolded protein binding;GO:0044183//protein binding involved in protein folding","GO:0006457//protein folding;GO:0051495//positive regulation of cytoskeleton organization","K09549//prefoldin subunit 2","XP_010614926.1//PREDICTED: prefoldin subunit 2 [Fukomys damarensis]","3//A2MP1"]
[10286,1310,12.05,11.98,-0.00840523832853827,1.00766456536371,"*",0.974736,"BCAS2","GO:0005654//nucleoplasm;GO:0000974//Prp19 complex;GO:0016607//nuclear speck;GO:0005813//centrosome;GO:0071013//catalytic step 2 spliceosome;GO:0005730//nucleolus;GO:0005681//spliceosomal complex;GO:0071011//precatalytic spliceosome;GO:0005662//DNA replication factor A complex","NA","GO:0006397//mRNA processing;GO:0000398//mRNA splicing, via spliceosome;GO:0008380//RNA splicing;GO:0000375//RNA splicing, via transesterification reactions","K12861//pre-mRNA-splicing factor SPF27","XP_008063201.1//pre-mRNA-splicing factor SPF27 isoform X1 [Carlito syrichta]","2//1"]
[64429,2207,26.01,25.86,-0.00834412413273694,0.899482800563116,"*",0.839964,"ZDHHC6","GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0016409//palmitoyltransferase activity;GO:0019706//protein-cysteine S-palmitoyltransferase activity","GO:0018345//protein palmitoylation","K20031//palmitoyltransferase ZDHHC6 [EC:2.3.1.225]","NP_001338015.1//palmitoyltransferase ZDHHC6 isoform 4 [Homo sapiens];NP_071939.1//palmitoyltransferase ZDHHC6 isoform 1 [Homo sapiens];NP_001290063.1//palmitoyltransferase ZDHHC6 isoform 2 [Homo sapiens];NP_001338014.1//palmitoyltransferase ZDHHC6 isoform 3 [Homo sapiens]","1//3;2//1"]
[54993,2245,8.88,8.83,-0.00814623870164012,0.468840506035198,"*",0.318538,"ZSCAN2","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0030154//cell differentiation;GO:0007275//multicellular organism development;GO:0006351//transcription, DNA-templated;GO:0007283//spermatogenesis","K09228//KRAB domain-containing zinc finger protein;K09230//SCAN domain-containing zinc finger protein","NP_060364.4//zinc finger and SCAN domain-containing protein 2 isoform 2 [Homo sapiens];NP_001007073.1//zinc finger and SCAN domain-containing protein 2 isoform 3 [Homo sapiens];XP_001086522.3//PREDICTED: zinc finger and SCAN domain-containing protein 2 [Macaca mulatta]","1//3;3//A2MP1;5"]
[120863,3216,1.78,1.77,-0.00812788088340034,1.02084400799845,"*",0.990744,"DEPDC4","GO:0005622//intracellular","NA","GO:0007165//signal transduction;GO:0035556//intracellular signal transduction","K01368//cathepsin S [EC:3.4.22.27];K08014//Rap guanine nucleotide exchange factor 3;K17985//activating molecule in BECN1-regulated autophagy protein 1","NP_001306240.1//DEP domain-containing protein 4 isoform 3 [Homo sapiens];NP_689530.1//DEP domain-containing protein 4 isoform 1 [Homo sapiens];NP_001306239.1//DEP domain-containing protein 4 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[5931,2018,80.69,80.24,-0.00806828385598765,0.954341793654955,"*",0.911446,"RBBP7","GO:0016581//NuRD complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0035098//ESC/E(Z) complex","GO:0004407//histone deacetylase activity;GO:0003723//RNA binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0043687//post-translational protein modification;GO:0030308//negative regulation of cell growth;GO:0006355//regulation of transcription, DNA-templated;GO:0006260//DNA replication;GO:0006351//transcription, DNA-templated;GO:0048545//response to steroid hormone;GO:1901796//regulation of signal transduction by p53 class mediator;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0070370//cellular heat acclimation;GO:0016569//covalent chromatin modification;GO:0007275//multicellular organism development;GO:0045814//negative regulation of gene expression, epigenetic;GO:0034080//CENP-A containing nucleosome assembly","K11659//histone-binding protein RBBP7","NP_002884.1//histone-binding protein RBBP7 isoform 2 [Homo sapiens];NP_001185648.1//histone-binding protein RBBP7 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[84289,4383,10.8,10.74,-8.03731906541842E-3,0.621401018139263,"*",0.46537,"ING5","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0070776//MOZ/MORF histone acetyltransferase complex","GO:0046872//metal ion binding;GO:0003682//chromatin binding;GO:0035064//methylated histone binding","GO:0045926//negative regulation of growth;GO:0006260//DNA replication;GO:0016573//histone acetylation;GO:0006351//transcription, DNA-templated;GO:0006473//protein acetylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:2001235//positive regulation of apoptotic signaling pathway;GO:1901796//regulation of signal transduction by p53 class mediator;GO:0043065//positive regulation of apoptotic process;GO:0043966//histone H3 acetylation;GO:0008285//negative regulation of cell proliferation","K11345//inhibitor of growth protein 5","XP_002723766.2//PREDICTED: inhibitor of growth protein 5 isoform X3 [Oryctolagus cuniculus];NP_001317090.1//inhibitor of growth protein 5 isoform 2 [Homo sapiens]","1//3;5"]
[2665,2399,116.07,115.43,-0.00797690866930126,0.631509509568451,"*",0.51026,"GDI2","GO:0034774//secretory granule lumen;GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005925//focal adhesion;GO:0031982//vesicle;GO:0005737//cytoplasm;GO:0035578//azurophil granule lumen;GO:0005829//cytosol;GO:0005576//extracellular region","GO:0031267//small GTPase binding;GO:0003723//RNA binding;GO:0005093//Rab GDP-dissociation inhibitor activity;GO:0005096//GTPase activator activity","GO:0007165//signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0043312//neutrophil degranulation;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0061024//membrane organization","K17255//Rab GDP dissociation inhibitor","NP_001108628.1//rab GDP dissociation inhibitor beta isoform 2 [Homo sapiens];BAE25494.1//unnamed protein product, partial [Mus musculus]","1//3;3//A2MP1"]
[6836,2926,139.99,139.22,-0.00795729377670972,0.835889348314607,"*",0.759124,"SURF4","GO:0030133//transport vesicle;GO:0016021//integral component of membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0035577//azurophil granule membrane;GO:0000139//Golgi membrane","NA","GO:0043312//neutrophil degranulation;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0010638//positive regulation of organelle organization;GO:0007030//Golgi organization","K20369//ER-derived vesicles protein","NP_001267718.1//surfeit locus protein 4 isoform 3 [Homo sapiens];NP_001267717.1//surfeit locus protein 4 isoform 2 [Homo sapiens];XP_008068997.2//surfeit locus protein 4 isoform X1 [Carlito syrichta];NP_149351.1//surfeit locus protein 4 isoform 1 [Homo sapiens];XP_016817488.1//PREDICTED: surfeit locus protein 4 isoform X1 [Pan troglodytes];XP_011517247.1//PREDICTED: surfeit locus protein 4 isoform X2 [Homo sapiens];CAF99172.1//unnamed protein product [Tetraodon nigroviridis]","1//3;3//A2MP1"]
[84270,943,52.46,52.18,-0.00772086344753222,0.966764287970759,"*",0.927244,"CARD19","GO:0005634//nucleus;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0031966//mitochondrial membrane;GO:0005789//endoplasmic reticulum membrane","GO:0050700//CARD domain binding","GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling","K11647//SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:3.6.4.-];K06836//disintegrin and metalloproteinase domain-containing protein 15 [EC:3.4.24.-];K07604//type I keratin, acidic","NP_115686.3//caspase recruitment domain-containing protein 19 isoform 1 [Homo sapiens];NP_001304940.1//caspase recruitment domain-containing protein 19 isoform 3 [Homo sapiens];NP_001304939.1//caspase recruitment domain-containing protein 19 isoform 2 [Homo sapiens]","4;1//3"]
[6623,861,5.66,5.63,-0.0076671307516528,0.973033145462836,"*",0.935084,"SNCG","GO:0070062//extracellular exosome;GO:0030424//axon;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0043025//neuronal cell body","NA","GO:0009306//protein secretion;GO:0007268//chemical synaptic transmission;GO:0008344//adult locomotory behavior;GO:0050808//synapse organization;GO:0046928//regulation of neurotransmitter secretion;GO:0014059//regulation of dopamine secretion","K04528//alpha-synuclein","NP_001317049.1//gamma-synuclein isoform 2 [Homo sapiens];XP_007960887.1//PREDICTED: gamma-synuclein isoform X1 [Chlorocebus sabaeus]","1//3;2//1"]
[84752,2722,11.4,11.34,-0.00761318410987521,0.997859158903932,"*",0.964314,"B3GNT9","NA","NA","NA","K18705//beta-1,3-N-acetylglucosaminyltransferase 9 [EC:2.4.1.-]","XP_011756226.1//PREDICTED: UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 isoform X1 [Macaca nemestrina]","2//1"]
[10965,1794,28.64,28.49,-0.00757587094040535,0.975373583599089,"*",0.938188,"ACOT2","NA","GO:0016790//thiolester hydrolase activity","GO:0006637//acyl-CoA metabolic process","K01068//acyl-coenzyme A thioesterase 1/2/4 [EC:3.1.2.2]","XP_014999556.1//PREDICTED: acyl-coenzyme A thioesterase 2, mitochondrial isoform X1 [Macaca mulatta]",5]
[118424,2280,23.3,23.18,-0.00744938853517087,0.960082753369096,"*",0.918732,"UBE2J2","GO:0005783//endoplasmic reticulum;GO:0000151//ubiquitin ligase complex;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0061630//ubiquitin protein ligase activity;GO:0005524//ATP binding;GO:0031625//ubiquitin protein ligase binding;GO:0061631//ubiquitin conjugating enzyme activity","GO:0006986//response to unfolded protein;GO:1903955//positive regulation of protein targeting to mitochondrion;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0016567//protein ubiquitination;GO:0000209//protein polyubiquitination","K04554//ubiquitin-conjugating enzyme E2 J2 [EC:2.3.2.23]","NP_477515.2//ubiquitin-conjugating enzyme E2 J2 isoform 2 [Homo sapiens];XP_008959957.1//PREDICTED: ubiquitin-conjugating enzyme E2 J2 isoform X1 [Pan paniscus];NP_919296.1//ubiquitin-conjugating enzyme E2 J2 isoform 1 [Homo sapiens]","1//3;2//1"]
[79139,3332,29.43,29.28,-0.00737198865635244,0.978418404108699,"*",0.942158,"DERL1","GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0005770//late endosome;GO:0048500//signal recognition particle;GO:0036502//Derlin-1-VIMP complex;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0036513//Derlin-1 retrotranslocation complex;GO:0005789//endoplasmic reticulum membrane;GO:0005769//early endosome;GO:0005785//signal recognition particle receptor complex","GO:0002020//protease binding;GO:0004872//receptor activity;GO:0031625//ubiquitin protein ligase binding;GO:0042288//MHC class I protein binding;GO:0051117//ATPase binding;GO:1990381//ubiquitin-specific protease binding","GO:0030970//retrograde protein transport, ER to cytosol;GO:0006986//response to unfolded protein;GO:0034620//cellular response to unfolded protein;GO:0016567//protein ubiquitination;GO:0051260//protein homooligomerization;GO:0032092//positive regulation of protein binding;GO:0036503//ERAD pathway;GO:0015031//protein transport;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0031648//protein destabilization;GO:0045184//establishment of protein localization;GO:0006457//protein folding;GO:0055085//transmembrane transport;GO:0071712//ER-associated misfolded protein catabolic process;GO:0031398//positive regulation of protein ubiquitination;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0016032//viral process","K11519//Derlin-1","XP_007126133.1//PREDICTED: derlin-1 isoform X1 [Physeter catodon];NP_001128143.1//derlin-1 isoform b [Homo sapiens];NP_077271.1//derlin-1 isoform a [Homo sapiens]","1//3;2//1;5"]
[23654,6356,29.72,29.57,-0.00729987241827203,0.966057887989556,"*",0.926506,"PLXNB2","GO:0070062//extracellular exosome;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane","GO:0017154//semaphorin receptor activity","GO:0007162//negative regulation of cell adhesion;GO:0010976//positive regulation of neuron projection development;GO:0050772//positive regulation of axonogenesis;GO:0008360//regulation of cell shape;GO:0007420//brain development;GO:0001932//regulation of protein phosphorylation;GO:0007405//neuroblast proliferation;GO:0043087//regulation of GTPase activity;GO:2001222//regulation of neuron migration;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0001843//neural tube closure;GO:0071526//semaphorin-plexin signaling pathway","K06821//plexin B","XP_011528984.1//PREDICTED: plexin-B2 isoform X1 [Homo sapiens]","3//A2MP1"]
[10712,3066,45.58,45.35,-0.00729837384941226,0.911700549019608,"*",0.855768,"FAM189B","GO:0016021//integral component of membrane","GO:0050699//WW domain binding","NA","K01201//glucosylceramidase [EC:3.2.1.45];K07412//cytochrome P450 family 2 subfamily B [EC:1.14.14.1]","NP_937995.1//protein FAM189B isoform b [Homo sapiens];XP_008968457.1//PREDICTED: LOW QUALITY PROTEIN: protein FAM189B [Pan paniscus]","1//3;2//1"]
[55742,8719,8.09,8.05,-0.00715091942799804,0.991259968103728,"*",0.957192,"PARVA","GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0030018//Z disc;GO:0005925//focal adhesion;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0030027//lamellipodium;GO:0005886//plasma membrane","GO:0003779//actin binding;GO:0045296//cadherin binding","GO:0003148//outflow tract septum morphogenesis;GO:0031532//actin cytoskeleton reorganization;GO:0034446//substrate adhesion-dependent cell spreading;GO:0070252//actin-mediated cell contraction;GO:0071670//smooth muscle cell chemotaxis;GO:0008360//regulation of cell shape;GO:0007155//cell adhesion;GO:0060271//cilium assembly;GO:0007163//establishment or maintenance of cell polarity;GO:0034113//heterotypic cell-cell adhesion;GO:0002040//sprouting angiogenesis","K06275//parvin","XP_002755106.3//PREDICTED: alpha-parvin [Callithrix jacchus]",4]
[54808,4983,6.11,6.08,-0.00710105637514406,0.97295008949391,"*",0.935126,"DYM","GO:0016020//membrane;GO:0005794//Golgi apparatus;GO:0005737//cytoplasm","GO:0019899//enzyme binding","GO:0060348//bone development;GO:0007030//Golgi organization","K02927//large subunit ribosomal protein L40e;K15696//RING finger protein 113B;K17985//activating molecule in BECN1-regulated autophagy protein 1;K01064//wingless-type MMTV integration site family, member 9","NP_001340141.1//dymeclin isoform 4 [Homo sapiens];NP_001340139.1//dymeclin isoform 2 [Homo sapiens];NP_001340145.1//dymeclin isoform 8 [Homo sapiens];NP_001340142.1//dymeclin isoform 5 [Homo sapiens];NP_001340143.1//dymeclin isoform 6 [Homo sapiens];NP_001340140.1//dymeclin isoform 3 [Homo sapiens];NP_060123.3//dymeclin isoform 1 [Homo sapiens];NP_001340144.1//dymeclin isoform 7 [Homo sapiens]","4;1//3"]
[127281,2749,18.61,18.52,-0.0069939567989151,0.940998688295417,"*",0.893342,"FAM213B","GO:0070062//extracellular exosome;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0043209//myelin sheath;GO:0005737//cytoplasm","GO:0016209//antioxidant activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0047017//prostaglandin-F synthase activity","GO:0001516//prostaglandin biosynthetic process;GO:0055114//oxidation-reduction process","K15717//prostamide/prostaglandin F2alpha synthase [EC:1.11.1.20]","NP_689584.2//prostamide/prostaglandin F synthase isoform b [Homo sapiens];NP_001182665.1//prostamide/prostaglandin F synthase isoform a [Homo sapiens];XP_009445112.1//PREDICTED: prostamide/prostaglandin F synthase isoform X1 [Pan troglodytes]","1//3;3//A2MP1"]
[5906,5036,4.18,4.16,-0.00691941393979047,0.956195502913638,"*",0.914234,"RAP1A","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005770//late endosome;GO:0043209//myelin sheath;GO:0030054//cell junction;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0043005//neuron projection;GO:0045335//phagocytic vesicle;GO:0005829//cytosol;GO:0035579//specific granule membrane;GO:0005886//plasma membrane;GO:0005769//early endosome;GO:0032045//guanyl-nucleotide exchange factor complex","GO:0008565//protein transporter activity;GO:0017034//Rap guanyl-nucleotide exchange factor activity;GO:0017016//Ras GTPase binding;GO:0005525//GTP binding;GO:0032403//protein complex binding;GO:0003924//GTPase activity","GO:0097421//liver regeneration;GO:0035690//cellular response to drug;GO:2000301//negative regulation of synaptic vesicle exocytosis;GO:0043547//positive regulation of GTPase activity;GO:1905451//positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis;GO:1990090//cellular response to nerve growth factor stimulus;GO:0071320//cellular response to cAMP;GO:0050796//regulation of insulin secretion;GO:0046326//positive regulation of glucose import;GO:0071407//cellular response to organic cyclic compound;GO:0007264//small GTPase mediated signal transduction;GO:0043312//neutrophil degranulation;GO:1901888//regulation of cell junction assembly;GO:0045860//positive regulation of protein kinase activity;GO:0015031//protein transport;GO:0000186//activation of MAPKK activity;GO:0007165//signal transduction;GO:0032966//negative regulation of collagen biosynthetic process;GO:2001214//positive regulation of vasculogenesis;GO:0010976//positive regulation of neuron projection development;GO:0071333//cellular response to glucose stimulus;GO:0097327//response to antineoplastic agent;GO:0038180//nerve growth factor signaling pathway;GO:0009743//response to carbohydrate;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0061028//establishment of endothelial barrier;GO:0032486//Rap protein signal transduction","K04353//Ras-related protein Rap-1A;K06235//zinc finger protein ZIC 2;K09349//homeobox protein Nkx-5","XP_004279208.1//PREDICTED: ras-related protein R-Ras2 isoform X1 [Orcinus orca];NP_002875.1//ras-related protein Rap-1A precursor [Homo sapiens];OXB61440.1//hypothetical protein ASZ78_015546 [Callipepla squamata]","1//3;3//A2MP1;2//1"]
[81932,1551,19.12,19.03,-0.0068069617067266,0.896015091958652,"*",0.83566,"HDHD3","GO:0005739//mitochondrion","GO:0016787//hydrolase activity","GO:0008152//metabolic process","K01698//porphobilinogen synthase [EC:4.2.1.24]","NP_112496.1//haloacid dehalogenase-like hydrolase domain-containing protein 3 [Homo sapiens]","1//3;3//A2MP1"]
[4724,675,34.02,33.86,-6.80116776774341E-3,1.01401287374749,"*",0.981956,"NDUFS4","GO:0045271//respiratory chain complex I;GO:0005747//mitochondrial respiratory chain complex I;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0016651//oxidoreductase activity, acting on NAD(P)H;GO:0008137//NADH dehydrogenase (ubiquinone) activity","GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0051591//response to cAMP;GO:0048146//positive regulation of fibroblast proliferation;GO:0072593//reactive oxygen species metabolic process;GO:0007420//brain development;GO:0019933//cAMP-mediated signaling;GO:0001932//regulation of protein phosphorylation;GO:0022900//electron transport chain;GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0045333//cellular respiration","K03937//NADH dehydrogenase (ubiquinone) Fe-S protein 4","NP_002486.1//NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial isoform 1 precursor [Homo sapiens];NP_001304980.1//NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial isoform 2 precursor [Homo sapiens]","1//3;3//A2MP1"]
[23135,6652,6.41,6.38,-6.76793285387166E-3,0.967525114779772,"*",0.928216,"KDM6B","GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0046872//metal ion binding;GO:0003682//chromatin binding;GO:0043565//sequence-specific DNA binding;GO:0071558//histone demethylase activity (H3-K27 specific);GO:0032452//histone demethylase activity;GO:0051213//dioxygenase activity;GO:0008013//beta-catenin binding","GO:0045165//cell fate commitment;GO:0055007//cardiac muscle cell differentiation;GO:0006338//chromatin remodeling;GO:0014823//response to activity;GO:0021766//hippocampus development;GO:0071557//histone H3-K27 demethylation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045446//endothelial cell differentiation;GO:0048333//mesodermal cell differentiation;GO:0060992//response to fungicide;GO:0070301//cellular response to hydrogen peroxide;GO:0002437//inflammatory response to antigenic stimulus","K11448//lysine-specific demethylase 6B [EC:1.14.11.-]","NP_001073893.1//lysine-specific demethylase 6B isoform 1 [Homo sapiens];NP_001335645.1//lysine-specific demethylase 6B isoform 2 [Homo sapiens]","1//3;2//1"]
[79134,5938,15.04,14.97,-0.00673034561922056,0.987033449640054,"*",0.95274,"TMEM185B","GO:0016021//integral component of membrane","NA","NA","K11447//histone demethylase [EC:1.14.11.-];K17776//metaxin;K01064//wingless-type MMTV integration site family, member 9","NP_077026.2//transmembrane protein 185B [Homo sapiens]","2//1"]
[23564,1409,15.09,15.02,-0.00670799301241158,0.929885270304316,"*",0.878018,"DDAH2","GO:0070062//extracellular exosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005739//mitochondrion","GO:0016403//dimethylargininase activity;GO:0016597//amino acid binding;GO:0003824//catalytic activity","GO:0050999//regulation of nitric-oxide synthase activity;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0007263//nitric oxide mediated signal transduction;GO:0043066//negative regulation of apoptotic process;GO:0006809//nitric oxide biosynthetic process;GO:0000052//citrulline metabolic process;GO:0006527//arginine catabolic process","K01482//dimethylargininase [EC:3.5.3.18]","XP_012596449.1//N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 isoform X2 [Microcebus murinus]","1//3;2//1"]
[55692,1716,21.83,21.73,-0.00662395580950797,0.780312383651381,"*",0.686034,"LUC7L","GO:0005685//U1 snRNP;GO:0071004//U2-type prespliceosome","GO:0050733//RS domain binding;GO:0003729//mRNA binding;GO:0042802//identical protein binding","GO:0006376//mRNA splice site selection;GO:0045843//negative regulation of striated muscle tissue development","K13212//RNA-binding protein Luc7-like 2","XP_017366351.1//PREDICTED: putative RNA-binding protein Luc7-like 1 isoform X1 [Cebus capucinus imitator];NP_958815.1//putative RNA-binding protein Luc7-like 1 isoform b [Homo sapiens]","4;1//3;2//1"]
[25963,3096,8.79,8.75,-0.00658014842371274,0.920734646628541,"*",0.866784,"TMEM87A","GO:0032580//Golgi cisterna membrane;GO:0005829//cytosol;GO:0016021//integral component of membrane","NA","GO:0042147//retrograde transport, endosome to Golgi","K02927//large subunit ribosomal protein L40e;K15696//RING finger protein 113B;K17985//activating molecule in BECN1-regulated autophagy protein 1","BAC11598.1//unnamed protein product [Homo sapiens];NP_001103973.1//transmembrane protein 87A isoform 2 precursor [Homo sapiens];NP_001273416.1//transmembrane protein 87A isoform 3 [Homo sapiens]","4;1//3;2//1"]
[9403,1789,48.46,48.24,-0.0065644975512616,1.00005434978624,"*",0.966498,"SELENOF","GO:0070062//extracellular exosome;GO:0005788//endoplasmic reticulum lumen","NA","GO:0051084//'de novo' posttranslational protein folding","NA","XP_005885381.2//PREDICTED: 15 kDa selenoprotein [Myotis brandtii];NP_976086.1//selenoprotein F isoform 2 precursor [Homo sapiens]","4;2//1"]
[199870,3425,2.23,2.22,-0.00648403357019863,0.970254158399061,"*",0.931806,"FAM76A","GO:0005654//nucleoplasm","NA","NA","K20394//sestrin 2;K01064//wingless-type MMTV integration site family, member 9","NP_001137386.1//protein FAM76A isoform 4 [Homo sapiens];NP_001137385.1//protein FAM76A isoform 2 [Homo sapiens];NP_689873.1//protein FAM76A isoform 3 [Homo sapiens];NP_001137387.1//protein FAM76A isoform 5 [Homo sapiens];NP_001137384.1//protein FAM76A isoform 1 [Homo sapiens]","1//3;2//1"]
[726,4393,9.03,8.99,-0.00640487196641073,1.00718717167271,"*",0.974022,"CAPN5","NA","NA","NA","K08574//calpain-5 [EC:3.4.22.-]","BAD92324.1//Hypothetical protein FLJ46245 variant, partial [Homo sapiens]",4]
[286053,1225,13.8,13.74,-0.00628626284743141,0.97467293665777,"*",0.93727,"NSMCE2","GO:0030915//Smc5-Smc6 complex;GO:0016605//PML body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000781//chromosome, telomeric region;GO:0016604//nuclear body","GO:0008270//zinc ion binding;GO:0004842//ubiquitin-protein transferase activity;GO:0019789//SUMO transferase activity;GO:0016874//ligase activity","GO:0000722//telomere maintenance via recombination;GO:0045842//positive regulation of mitotic metaphase/anaphase transition;GO:0034184//positive regulation of maintenance of mitotic sister chromatid cohesion;GO:0090398//cellular senescence;GO:0051301//cell division;GO:0000724//double-strand break repair via homologous recombination;GO:0007049//cell cycle","NA","NP_001336416.1//E3 SUMO-protein ligase NSE2 isoform 2 [Homo sapiens];XP_001152705.2//PREDICTED: E3 SUMO-protein ligase NSE2 isoform X2 [Pan troglodytes]","1//3;3//A2MP1"]
[54902,3523,16.57,16.5,-6.10757808827379E-3,1.0005310761658,"*",0.967084,"TTC19","GO:0005743//mitochondrial inner membrane;GO:0005813//centrosome;GO:0070469//respiratory chain;GO:0005739//mitochondrion;GO:0030496//midbody","NA","GO:0034551//mitochondrial respiratory chain complex III assembly;GO:0000910//cytokinesis;GO:0055114//oxidation-reduction process","K18169//tetratricopeptide repeat protein 19, mitochondrial","XP_004042270.2//PREDICTED: tetratricopeptide repeat protein 19, mitochondrial isoform X1 [Gorilla gorilla gorilla];AAI05129.1//Tetratricopeptide repeat domain 19 [Homo sapiens]","1//3;3//A2MP1"]
[112611,3904,2.38,2.37,-0.00607451440968423,0.950210588096177,"*",0.905478,"RWDD2A","NA","NA","NA","K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K02927//large subunit ribosomal protein L40e;K17985//activating molecule in BECN1-regulated autophagy protein 1;K12025//tripartite motif-containing protein 52","XP_015354503.1//PREDICTED: RWD domain-containing protein 2A isoform X2 [Marmota marmota marmota];NP_219479.2//RWD domain-containing protein 2A isoform a [Homo sapiens];XP_018885074.1//PREDICTED: RWD domain-containing protein 2A isoform X2 [Gorilla gorilla gorilla]","4;1//3"]
[10179,3749,4.85,4.83,-0.00596155823871668,1.01202425955878,"*",0.97927,"RBM7","GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0003723//RNA binding;GO:0003727//single-stranded RNA binding","GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0051321//meiotic cell cycle","K13188//RNA-binding protein 7","NP_057174.1//RNA-binding protein 7 isoform b [Homo sapiens];NP_001272974.1//RNA-binding protein 7 isoform a [Homo sapiens]","1//3;3//A2MP1"]
[8846,2585,7.72,7.69,-0.00561724930625392,1.01385220095694,"*",0.98161,"ALKBH1","GO:0005719//nuclear euchromatin;GO:0005739//mitochondrion","GO:0003906//DNA-(apurinic or apyrimidinic site) lyase activity;GO:0000049//tRNA binding;GO:0070579//methylcytosine dioxygenase activity;GO:0043734//DNA-N1-methyladenine dioxygenase activity;GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;GO:0140078//class I DNA-(apurinic or apyrimidinic site) lyase activity;GO:0042056//chemoattractant activity;GO:0140080//class III/IV DNA-(apurinic or apyrimidinic site) lyase activity;GO:0016491//oxidoreductase activity;GO:1990984//tRNA demethylase activity;GO:0103053//1-ethyladenine demethylase activity;GO:0008198//ferrous iron binding","GO:1990983//tRNA demethylation;GO:0070989//oxidative demethylation;GO:0006448//regulation of translational elongation;GO:0080111//DNA demethylation;GO:0001890//placenta development;GO:0002101//tRNA wobble cytosine modification;GO:0006307//DNA dealkylation involved in DNA repair;GO:0031175//neuron projection development;GO:0006281//DNA repair;GO:0043524//negative regulation of neuron apoptotic process;GO:0035552//oxidative single-stranded DNA demethylation;GO:0001701//in utero embryonic development;GO:0042245//RNA repair;GO:0070129//regulation of mitochondrial translation;GO:0006446//regulation of translational initiation;GO:0001764//neuron migration;GO:0048589//developmental growth","K10765//alkylated DNA repair protein alkB homolog 1 [EC:1.14.11.- 4.2.99.18]","NP_006011.2//nucleic acid dioxygenase ALKBH1 [Homo sapiens]","2//1"]
[23413,4928,27.34,27.24,-0.00528653959398898,0.973133541967832,"*",0.935546,"NCS1","GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0030425//dendrite;GO:0030424//axon;GO:0031410//cytoplasmic vesicle;GO:0030054//cell junction;GO:0005737//cytoplasm;GO:0014069//postsynaptic density;GO:0048471//perinuclear region of cytoplasm;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0031045//dense core granule;GO:0005886//plasma membrane;GO:0045211//postsynaptic membrane","GO:0000287//magnesium ion binding;GO:0005245//voltage-gated calcium channel activity;GO:0005509//calcium ion binding;GO:0008427//calcium-dependent protein kinase inhibitor activity;GO:0019901//protein kinase binding","GO:0050806//positive regulation of synaptic transmission;GO:0045921//positive regulation of exocytosis;GO:0048015//phosphatidylinositol-mediated signaling;GO:0010975//regulation of neuron projection development","K19932//neuronal calcium sensor 1","EHA99921.1//Neuronal calcium sensor 1 [Heterocephalus glaber];NP_062655.1//neuronal calcium sensor 1 [Mus musculus]","1//3;3//A2MP1"]
[5316,5046,2.78,2.77,-0.00519890667431923,0.91480718667111,"*",0.859314,"PKNOX1","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005667//transcription factor complex;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0046982//protein heterodimerization activity;GO:0003700//DNA binding transcription factor activity;GO:0003705//transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding","GO:0043010//camera-type eye development;GO:0001525//angiogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0030217//T cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0030218//erythrocyte differentiation","K16672//homeobox protein homothorax;K16670//homeobox protein Meis2;K15613//homeobox protein Meis1;K16671//homeobox protein Meis3","NP_004562.2//homeobox protein PKNOX1 isoform 1 [Homo sapiens];XP_012300320.1//homeobox protein PKNOX1 isoform X3 [Aotus nancymaae];NP_001307623.1//homeobox protein PKNOX1 isoform 3 [Homo sapiens]","4;1//3"]
[79087,2387,11.19,11.15,-0.00516632616872677,1.01968655308164,"*",0.98911,"ALG12","GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0000009//alpha-1,6-mannosyltransferase activity;GO:0016757//transferase activity, transferring glycosyl groups;GO:0000030//mannosyltransferase activity;GO:0052917//dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity","GO:0006457//protein folding;GO:0006487//protein N-linked glycosylation;GO:0006488//dolichol-linked oligosaccharide biosynthetic process","K03847//alpha-1,6-mannosyltransferase [EC:2.4.1.260]","NP_077010.1//dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase [Homo sapiens]","3//A2MP1"]
[10013,4089,14.16,14.11,-5.10327748573337E-3,1.00387756928257,"*",0.97057,"HDAC6","GO:0030425//dendrite;GO:0031252//cell leading edge;GO:0030424//axon;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005881//cytoplasmic microtubule;GO:0016235//aggresome;GO:0043204//perikaryon;GO:0005901//caveola;GO:0043234//protein complex;GO:0005829//cytosol","GO:0032041//NAD-dependent histone deacetylase activity (H3-K14 specific);GO:0042903//tubulin deacetylase activity;GO:0008017//microtubule binding;GO:0003779//actin binding;GO:0043130//ubiquitin binding;GO:0048487//beta-tubulin binding;GO:0043014//alpha-tubulin binding;GO:0008270//zinc ion binding;GO:0008013//beta-catenin binding","GO:0006355//regulation of transcription, DNA-templated;GO:0060997//dendritic spine morphogenesis;GO:0048668//collateral sprouting;GO:0007026//negative regulation of microtubule depolymerization;GO:0006914//autophagy;GO:0071218//cellular response to misfolded protein;GO:0070201//regulation of establishment of protein localization;GO:0000209//protein polyubiquitination;GO:0043241//protein complex disassembly;GO:0070301//cellular response to hydrogen peroxide;GO:0098779//positive regulation of mitophagy in response to mitochondrial depolarization;GO:0045598//regulation of fat cell differentiation;GO:0070846//Hsp90 deacetylation;GO:0051646//mitochondrion localization;GO:0006351//transcription, DNA-templated;GO:0070842//aggresome assembly;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway","K11407//histone deacetylase 6 [EC:3.5.1.98]","EAW50744.1//histone deacetylase 6, isoform CRA_a [Homo sapiens];EHH30703.1//Histone deacetylase 6 [Macaca mulatta];XP_016799016.1//PREDICTED: histone deacetylase 6 [Pan troglodytes]","1//3;3//A2MP1"]
[84060,4703,2.85,2.84,-0.00507098954742214,1.01689338947368,"*",0.985764,"RBM48","GO:0005654//nucleoplasm","GO:0003723//RNA binding;GO:0003676//nucleic acid binding","NA","K17985//activating molecule in BECN1-regulated autophagy protein 1;K15696//RING finger protein 113B","AAH33561.1//C7orf64 protein, partial [Homo sapiens]","3//A2MP1"]
[9831,3979,5.79,5.77,-0.00499202934375419,0.911156533600267,"*",0.854744,"ZNF623","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_005215331.1//PREDICTED: zinc finger protein 623 [Bos taurus]","1//3;3//A2MP1;2//1"]
[7374,2081,41.46,41.32,-0.00487986224435524,1.00073337205947,"*",0.998666,"UNG","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion","GO:0003684//damaged DNA binding;GO:0004844//uracil DNA N-glycosylase activity;GO:0043024//ribosomal small subunit binding","GO:0006281//DNA repair;GO:0006284//base-excision repair;GO:0016446//somatic hypermutation of immunoglobulin genes;GO:0016447//somatic recombination of immunoglobulin gene segments;GO:0043066//negative regulation of apoptotic process;GO:0016032//viral process;GO:0045830//positive regulation of isotype switching;GO:0045008//depyrimidination;GO:0097510//base-excision repair, AP site formation via deaminated base removal","K03648//uracil-DNA glycosylase [EC:3.2.2.27]","XP_008002807.1//PREDICTED: uracil-DNA glycosylase isoform X1 [Chlorocebus sabaeus];NP_003353.1//uracil-DNA glycosylase isoform UNG1 precursor [Homo sapiens]","3//A2MP1;2//1"]
[221079,7277,2.98,2.97,-0.00484939966139585,1.01545152690395,"*",0.984112,"ARL5B","GO:0005622//intracellular","GO:0005525//GTP binding","GO:1903292//protein localization to Golgi membrane;GO:0007264//small GTPase mediated signal transduction","K07950//ADP-ribosylation factor-like protein 5B","NP_083742.2//ADP-ribosylation factor-like protein 5B [Mus musculus]",4]
[51005,1808,15.02,14.97,-0.00481059145585491,0.737754759221609,"*",0.636056,"AMDHD2","GO:0005634//nucleus;GO:0005829//cytosol","GO:0046872//metal ion binding;GO:0008448//N-acetylglucosamine-6-phosphate deacetylase activity","GO:0006044//N-acetylglucosamine metabolic process;GO:0006046//N-acetylglucosamine catabolic process;GO:0006048//UDP-N-acetylglucosamine biosynthetic process;GO:0005975//carbohydrate metabolic process;GO:0019262//N-acetylneuraminate catabolic process","K01443//N-acetylglucosamine-6-phosphate deacetylase [EC:3.5.1.25]","NP_001317378.1//N-acetylglucosamine-6-phosphate deacetylase isoform 3 [Homo sapiens];NP_057028.2//N-acetylglucosamine-6-phosphate deacetylase isoform 1 [Homo sapiens];NP_001139287.1//N-acetylglucosamine-6-phosphate deacetylase isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[10797,2208,69.47,69.24,-0.00478437262646308,1.00375638541734,"*",0.97039,"MTHFD2","GO:0005759//mitochondrial matrix;GO:0005615//extracellular space;GO:0005739//mitochondrion","GO:0004488//methylenetetrahydrofolate dehydrogenase (NADP+) activity;GO:0000287//magnesium ion binding;GO:0042301//phosphate ion binding;GO:0004477//methenyltetrahydrofolate cyclohydrolase activity;GO:0004487//methylenetetrahydrofolate dehydrogenase (NAD+) activity","GO:0046653//tetrahydrofolate metabolic process;GO:0006730//one-carbon metabolic process;GO:0046655//folic acid metabolic process","K13403//methylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.15 3.5.4.9]","XP_007968376.1//PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Chlorocebus sabaeus]","3//A2MP1"]
[7869,2687,3.17,3.16,-0.0045582819623043,0.850285239328537,"*",0.776882,"SEMA3B","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum","GO:0038191//neuropilin binding","GO:0007267//cell-cell signaling;GO:0050919//negative chemotaxis;GO:0007411//axon guidance","K06840//semaphorin 3","NP_004627.1//semaphorin-3B isoform 1 precursor [Homo sapiens];NP_001276990.1//semaphorin-3B isoform 3 precursor [Homo sapiens];NP_001005914.1//semaphorin-3B isoform 2 precursor [Homo sapiens];AAH44602.1//SEMA3B protein, partial [Homo sapiens]","1//3;3//A2MP1;2//1"]
[347240,6286,3.44,3.43,-0.00419998852928546,1.0154201248062,"*",0.984018,"KIF24","GO:0005814//centriole;GO:0005874//microtubule;GO:0043234//protein complex;GO:0005829//cytosol;GO:0005871//kinesin complex","GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0003777//microtubule motor activity;GO:0008017//microtubule binding;GO:0016887//ATPase activity","GO:0007018//microtubule-based movement;GO:0060271//cilium assembly;GO:0097711//ciliary basal body-plasma membrane docking;GO:0007019//microtubule depolymerization","K10393//kinesin family member 2/24","XP_011516163.1//PREDICTED: kinesin-like protein KIF24 isoform X1 [Homo sapiens]","3//A2MP1"]
[8504,2774,3.54,3.53,-4.08117681181703E-3,1.01884375025826,"*",0.987846,"PEX3","GO:0016020//membrane;GO:0005654//nucleoplasm;GO:0005783//endoplasmic reticulum;GO:0032994//protein-lipid complex;GO:0005777//peroxisome;GO:0005779//integral component of peroxisomal membrane;GO:0005829//cytosol;GO:0043234//protein complex;GO:0005778//peroxisomal membrane","GO:0008289//lipid binding;GO:0046983//protein dimerization activity","GO:0007031//peroxisome organization;GO:0055085//transmembrane transport;GO:0016557//peroxisome membrane biogenesis;GO:0045046//protein import into peroxisome membrane","K13336//peroxin-3","NP_003621.1//peroxisomal biogenesis factor 3 [Homo sapiens]","2//1"]
[1522,1517,81.52,81.29,-0.00407616338236538,1.01623612349826,"*",0.984936,"CTSZ","GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0031410//cytoplasmic vesicle;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0000139//Golgi membrane;GO:0030134//COPII-coated ER to Golgi transport vesicle;GO:0030426//growth cone;GO:1904813//ficolin-1-rich granule lumen;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0070062//extracellular exosome;GO:0043231//intracellular membrane-bounded organelle;GO:0099738//cell cortex region;GO:0035580//specific granule lumen;GO:0005764//lysosome;GO:0009986//cell surface","GO:0004180//carboxypeptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0004197//cysteine-type endopeptidase activity","GO:0043525//positive regulation of neuron apoptotic process;GO:0060441//epithelial tube branching involved in lung morphogenesis;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0010757//negative regulation of plasminogen activation;GO:0048208//COPII vesicle coating;GO:2000179//positive regulation of neural precursor cell proliferation;GO:0006508//proteolysis;GO:0010977//negative regulation of neuron projection development;GO:0002003//angiotensin maturation;GO:0032091//negative regulation of protein binding;GO:0043312//neutrophil degranulation;GO:0006888//ER to Golgi vesicle-mediated transport;GO:1901214//regulation of neuron death","K08568//cathepsin X [EC:3.4.18.1]","EAW75449.1//cathepsin Z, isoform CRA_b [Homo sapiens]","3//A2MP1"]
[3140,7761,3.63,3.62,-0.00397985091254521,0.994122961570864,"*",0.96033,"MR1","GO:0005783//endoplasmic reticulum;GO:0042612//MHC class I protein complex;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane","GO:0032393//MHC class I receptor activity","GO:0050829//defense response to Gram-negative bacterium;GO:0032620//interleukin-17 production;GO:0006955//immune response;GO:0045087//innate immune response;GO:0002367//cytokine production involved in immune response;GO:0032611//interleukin-1 beta production;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I","K06751//major histocompatibility complex, class I","XP_016773699.1//PREDICTED: major histocompatibility complex class I-related gene protein isoform X5 [Pan troglodytes];XP_007987490.1//PREDICTED: major histocompatibility complex class I-related gene protein isoform X1 [Chlorocebus sabaeus];NP_001181928.1//major histocompatibility complex class I-related gene protein isoform 2 precursor [Homo sapiens];XP_017807155.1//major histocompatibility complex class I-related gene protein isoform X4 [Papio anubis];XP_007987492.1//PREDICTED: major histocompatibility complex class I-related gene protein isoform X3 [Chlorocebus sabaeus]","1//3;2//1"]
[57799,2616,10.92,10.89,-0.00396890220294556,0.984030735612794,"*",0.949472,"RAB40C","GO:0005768//endosome;GO:0030667//secretory granule membrane;GO:0008021//synaptic vesicle;GO:0005622//intracellular;GO:0005886//plasma membrane;GO:0048471//perinuclear region of cytoplasm","GO:0019003//GDP binding;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0072659//protein localization to plasma membrane;GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction","K07928//Ras-related protein Rab-40","NP_001166137.1//ras-related protein Rab-40C isoform b [Homo sapiens];XP_005081763.2//ras-related protein Rab-40C [Mesocricetus auratus]","4;1//3"]
[162427,3818,15.3,15.26,-0.0037766907454838,1.01897185848021,"*",0.988034,"RETREG3","GO:0016021//integral component of membrane","NA","GO:0010976//positive regulation of neuron projection development","K12855//pre-mRNA-processing factor 6;K01064//wingless-type MMTV integration site family, member 9","XP_004041670.2//PREDICTED: protein FAM134C isoform X1 [Gorilla gorilla gorilla]","3//A2MP1"]
[23293,4146,15.55,15.51,-0.00371589398187411,0.0138670594975576,"*",0.00497596,"SMG6","GO:0005634//nucleus;GO:0000781//chromosome, telomeric region;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005697//telomerase holoenzyme complex;GO:0035145//exon-exon junction complex;GO:0000333//telomerase catalytic core complex","GO:0003723//RNA binding;GO:0070182//DNA polymerase binding;GO:0004521//endoribonuclease activity;GO:0046872//metal ion binding;GO:0042162//telomeric DNA binding;GO:0043021//ribonucleoprotein complex binding;GO:0004540//ribonuclease activity;GO:0070034//telomerase RNA binding","GO:0006406//mRNA export from nucleus;GO:0032210//regulation of telomere maintenance via telomerase;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:1904354//negative regulation of telomere capping;GO:0051972//regulation of telomerase activity;GO:0035303//regulation of dephosphorylation;GO:0007004//telomere maintenance via telomerase;GO:0032204//regulation of telomere maintenance;GO:0043487//regulation of RNA stability","K11124//protein SMG6 [EC:3.1.-.-]","NP_001269255.1//telomerase-binding protein EST1A isoform 4 [Homo sapiens];EAW90558.1//hCG1813980, isoform CRA_c, partial [Homo sapiens];XP_016786654.1//PREDICTED: telomerase-binding protein EST1A isoform X3 [Pan troglodytes]","1//3;4"]
[5547,3670,19.73,19.68,-0.00366073538431879,0.919533934788395,"*",0.865078,"PRCP","GO:0070062//extracellular exosome;GO:0101003//ficolin-1-rich granule membrane;GO:0005764//lysosome;GO:0005886//plasma membrane;GO:0045178//basal part of cell;GO:0035577//azurophil granule membrane","GO:0004180//carboxypeptidase activity;GO:0004185//serine-type carboxypeptidase activity;GO:0008236//serine-type peptidase activity;GO:0008239//dipeptidyl-peptidase activity","GO:0043535//regulation of blood vessel endothelial cell migration;GO:0003085//negative regulation of systemic arterial blood pressure;GO:0007597//blood coagulation, intrinsic pathway;GO:0060055//angiogenesis involved in wound healing;GO:0042593//glucose homeostasis;GO:0097009//energy homeostasis;GO:0006508//proteolysis;GO:0043312//neutrophil degranulation;GO:2000377//regulation of reactive oxygen species metabolic process;GO:0002155//regulation of thyroid hormone mediated signaling pathway;GO:0002353//plasma kallikrein-kinin cascade","K01285//lysosomal Pro-X carboxypeptidase [EC:3.4.16.2]","NP_955450.2//lysosomal Pro-X carboxypeptidase isoform 2 precursor [Homo sapiens];NP_005031.1//lysosomal Pro-X carboxypeptidase isoform 1 preproprotein [Homo sapiens]","1//3;3//A2MP1"]
[102288414,666,96.94,96.7,-0.0035761928021965,1.01983310428498,"*",0.989316,"C11orf98","NA","NA","NA","NA","NP_001273015.1//uncharacterized protein C11orf98 [Homo sapiens]","1//3"]
[26063,1599,20.46,20.41,-0.00352996271260948,1.02172335495495,"*",0.993964,"DECR2","GO:0005777//peroxisome;GO:0005778//peroxisomal membrane","GO:0019166//trans-2-enoyl-CoA reductase (NADPH) activity;GO:0005102//receptor binding;GO:0008670//2,4-dienoyl-CoA reductase (NADPH) activity","GO:0006636//unsaturated fatty acid biosynthetic process;GO:0006631//fatty acid metabolic process;GO:0033540//fatty acid beta-oxidation using acyl-CoA oxidase","K13237//peroxisomal 2,4-dienoyl-CoA reductase [EC:1.3.1.34]","NP_065715.1//peroxisomal 2,4-dienoyl-CoA reductase [Homo sapiens]","3//A2MP1"]
[291,4420,4.1,4.09,-3.52306656369722E-3,1.01505754500226,"*",0.983476,"SLC25A4","GO:0005634//nucleus;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0043209//myelin sheath;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0005471//ATP:ADP antiporter activity;GO:0015207//adenine transmembrane transporter activity;GO:0005215//transporter activity","GO:0006810//transport;GO:0055085//transmembrane transport;GO:0046902//regulation of mitochondrial membrane permeability;GO:0006091//generation of precursor metabolites and energy;GO:0008637//apoptotic mitochondrial changes;GO:0060546//negative regulation of necroptotic process;GO:0016032//viral process;GO:0050796//regulation of insulin secretion;GO:0000002//mitochondrial genome maintenance;GO:0015866//ADP transport","K05863//solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31","NP_001142.2//ADP/ATP translocase 1 [Homo sapiens]","3//A2MP1"]
[23125,4468,26.08,26.02,-3.32290751328206E-3,0.643671907407407,"*",0.487408,"CAMTA2","GO:0005634//nucleus","GO:0042826//histone deacetylase binding;GO:0003682//chromatin binding;GO:0043565//sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0008134//transcription factor binding","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0014898//cardiac muscle hypertrophy in response to stress","K21596//calmodulin-binding transcription activator","NP_001164639.1//calmodulin-binding transcription activator 2 isoform 3 [Homo sapiens];NP_001164638.1//calmodulin-binding transcription activator 2 isoform 4 [Homo sapiens];NP_001164637.1//calmodulin-binding transcription activator 2 isoform 2 [Homo sapiens];XP_011522049.1//PREDICTED: calmodulin-binding transcription activator 2 isoform X2 [Homo sapiens]","1//3;3//A2MP1"]
[9180,3994,27.14,27.08,-0.00319298184385746,0.921054042553191,"*",0.8672,"OSMR","GO:0016324//apical plasma membrane;GO:0005900//oncostatin-M receptor complex;GO:0005886//plasma membrane","GO:0004924//oncostatin-M receptor activity;GO:0004896//cytokine receptor activity;GO:0019838//growth factor binding","GO:0002675//positive regulation of acute inflammatory response;GO:0038165//oncostatin-M-mediated signaling pathway;GO:0034097//response to cytokine;GO:0008284//positive regulation of cell proliferation","K05057//oncostatin M receptor","NP_001161827.1//oncostatin-M-specific receptor subunit beta isoform 2 precursor [Homo sapiens];NP_001310436.1//oncostatin-M-specific receptor subunit beta isoform 4 precursor [Homo sapiens];NP_001310435.1//oncostatin-M-specific receptor subunit beta isoform 3 precursor [Homo sapiens];NP_003990.1//oncostatin-M-specific receptor subunit beta isoform 1 precursor [Homo sapiens]","1//3;2//1"]
[81554,2425,31.9,31.83,-0.00316926701631082,1.01648800204095,"*",0.997716,"RCC1L","GO:0005739//mitochondrion","GO:0003723//RNA binding","NA","K10615//E3 ubiquitin-protein ligase HERC4 [EC:2.3.2.26]","NP_683682.1//RCC1-like G exchanging factor-like protein isoform 2 [Homo sapiens];NP_110425.2//RCC1-like G exchanging factor-like protein isoform 1 [Homo sapiens];NP_001268370.1//RCC1-like G exchanging factor-like protein isoform 3 [Homo sapiens]","4;1//3;2//1"]
[129685,4323,9.22,9.2,-0.00313288948496302,0.999358,"*",0.999358,"TAF8","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005669//transcription factor TFIID complex;GO:0048471//perinuclear region of cytoplasm","GO:0003743//translation initiation factor activity;GO:0046982//protein heterodimerization activity","GO:0042795//snRNA transcription from RNA polymerase II promoter;GO:0045598//regulation of fat cell differentiation;GO:0030154//cell differentiation;GO:0001833//inner cell mass cell proliferation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051457//maintenance of protein location in nucleus","K14649//transcription initiation factor TFIID subunit 8","NP_612639.2//transcription initiation factor TFIID subunit 8 [Homo sapiens]","2//1"]
[163071,2527,4.61,4.6,-0.00313288948496302,1.01785923647165,"*",0.986764,"ZNF114","GO:0005622//intracellular","GO:0046872//metal ion binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","XP_011936105.1//PREDICTED: zinc finger protein 114 [Cercocebus atys]","1//3;3//A2MP1"]
[54819,2216,4.82,4.81,-0.00299625245991967,1.01850933634661,"*",0.987458,"ZCCHC10","NA","GO:0008270//zinc ion binding;GO:0003676//nucleic acid binding","NA","K14438//chromodomain-helicase-DNA-binding protein 9 [EC:3.6.4.12];K08337//ubiquitin-like modifier-activating enzyme ATG7;K19613//leucine-rich repeat protein SHOC2;K13172//serine/arginine repetitive matrix protein 2","XP_531905.2//zinc finger CCHC domain-containing protein 10 isoform X2 [Canis lupus familiaris];OXB54752.1//hypothetical protein ASZ78_005815 [Callipepla squamata];NP_001033634.1//zinc finger CCHC domain-containing protein 10 [Bos taurus]","1//3;3//A2MP1;2//1"]
[11238,6032,4.99,4.98,-0.0028940732691796,1.02192617262941,"*",0.992434,"CA5B","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0008270//zinc ion binding;GO:0004089//carbonate dehydratase activity","GO:0015701//bicarbonate transport;GO:0006730//one-carbon metabolic process","K01672//carbonic anhydrase [EC:4.2.1.1]","NP_009151.1//carbonic anhydrase 5B, mitochondrial precursor [Homo sapiens]","3//A2MP1"]
[382,3939,35.82,35.75,-0.00282209543284716,1.02169259992279,"*",0.994062,"ARF6","GO:0016020//membrane;GO:0005938//cell cortex;GO:0005737//cytoplasm;GO:0055038//recycling endosome membrane;GO:0005829//cytosol;GO:0042584//chromaffin granule membrane;GO:0055037//recycling endosome;GO:0005886//plasma membrane;GO:0005769//early endosome;GO:0031527//filopodium membrane;GO:0070382//exocytic vesicle;GO:0070062//extracellular exosome;GO:0005925//focal adhesion;GO:0005622//intracellular;GO:0043209//myelin sheath;GO:0090543//Flemming body;GO:0005768//endosome;GO:0001726//ruffle;GO:0030139//endocytic vesicle;GO:0032154//cleavage furrow;GO:0005794//Golgi apparatus","GO:0031681//G-protein beta-subunit binding;GO:0047485//protein N-terminus binding;GO:0031996//thioesterase binding;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0097284//hepatocyte apoptotic process;GO:0060998//regulation of dendritic spine development;GO:2000171//negative regulation of dendrite development;GO:0030866//cortical actin cytoskeleton organization;GO:0090162//establishment of epithelial cell polarity;GO:0016192//vesicle-mediated transport;GO:0034143//regulation of toll-like receptor 4 signaling pathway;GO:0007264//small GTPase mediated signal transduction;GO:1903078//positive regulation of protein localization to plasma membrane;GO:0030838//positive regulation of actin filament polymerization;GO:0033028//myeloid cell apoptotic process;GO:0015031//protein transport;GO:0050432//catecholamine secretion;GO:0051489//regulation of filopodium assembly;GO:0031529//ruffle organization;GO:0036010//protein localization to endosome;GO:0030036//actin cytoskeleton organization;GO:0001889//liver development;GO:0048261//negative regulation of receptor-mediated endocytosis;GO:0031584//activation of phospholipase D activity;GO:0061024//membrane organization;GO:0035020//regulation of Rac protein signal transduction;GO:0006928//movement of cell or subcellular component;GO:0007155//cell adhesion;GO:0051301//cell division;GO:0007049//cell cycle;GO:0034394//protein localization to cell surface","K07941//ADP-ribosylation factor 6","XP_005376889.2//PREDICTED: ADP-ribosylation factor 6 [Chinchilla lanigera]","3//A2MP1"]
[10670,1657,87.77,87.6,-0.00279703750668702,1.02178063301571,"*",0.993508,"RRAGA","GO:0005765//lysosomal membrane;GO:0005634//nucleus;GO:1990131//Gtr1-Gtr2 GTPase complex;GO:0034448//EGO complex;GO:0005829//cytosol;GO:1990130//GATOR1 complex;GO:0005764//lysosome;GO:0005737//cytoplasm","GO:0031625//ubiquitin protein ligase binding;GO:0046982//protein heterodimerization activity;GO:0005525//GTP binding;GO:0042803//protein homodimerization activity;GO:0051219//phosphoprotein binding;GO:0003924//GTPase activity","GO:0034198//cellular response to amino acid starvation;GO:0043200//response to amino acid;GO:0009267//cellular response to starvation;GO:0016567//protein ubiquitination;GO:0007050//cell cycle arrest;GO:0032008//positive regulation of TOR signaling;GO:0010506//regulation of autophagy;GO:1904263//positive regulation of TORC1 signaling;GO:0016241//regulation of macroautophagy;GO:0045919//positive regulation of cytolysis;GO:0042268//regulation of cytolysis;GO:0008219//cell death;GO:0006915//apoptotic process;GO:0071230//cellular response to amino acid stimulus;GO:1903432//regulation of TORC1 signaling;GO:0010507//negative regulation of autophagy;GO:0034613//cellular protein localization;GO:0019048//modulation by virus of host morphology or physiology","K16185//Ras-related GTP-binding protein A/B","AAH37615.1//Rraga protein, partial [Mus musculus]",4]
[1326,2951,5.28,5.27,-0.00273496772123906,1.00764612349515,"*",0.974592,"MAP3K8","GO:0005829//cytosol","GO:0005524//ATP binding;GO:0004672//protein kinase activity","NA","K04415//mitogen-activated protein kinase kinase kinase 8 [EC:2.7.11.25]","XP_018891147.1//PREDICTED: mitogen-activated protein kinase kinase kinase 8 isoform X1 [Gorilla gorilla gorilla];XP_019509950.1//PREDICTED: mitogen-activated protein kinase kinase kinase 8 isoform X1 [Hipposideros armiger]","1//3;3//A2MP1"]
[54788,3596,21.99,21.95,-0.00262666443224754,0.949216922915161,"*",0.904234,"DNAJB12","GO:0016020//membrane;GO:0031965//nuclear membrane;GO:0005783//endoplasmic reticulum;GO:0030176//integral component of endoplasmic reticulum membrane","GO:0030544//Hsp70 protein binding","GO:0036503//ERAD pathway;GO:0051085//chaperone cofactor-dependent protein refolding;GO:0071218//cellular response to misfolded protein;GO:0043623//cellular protein complex assembly","K09518//DnaJ homolog subfamily B member 12","NP_001002762.2//dnaJ homolog subfamily B member 12 [Homo sapiens]","4;2//1"]
[7536,3187,175.39,175.12,-0.00222263409366299,0.785678701133145,"*",0.69449,"SF1","GO:0005840//ribosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0016604//nuclear body","GO:0003723//RNA binding;GO:0003714//transcription corepressor activity;GO:0045131//pre-mRNA branch point binding;GO:0042802//identical protein binding;GO:0008270//zinc ion binding","GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0000398//mRNA splicing, via spliceosome;GO:0006355//regulation of transcription, DNA-templated;GO:0030575//nuclear body organization;GO:0030238//male sex determination;GO:0006351//transcription, DNA-templated;GO:0050810//regulation of steroid biosynthetic process;GO:0000389//mRNA 3'-splice site recognition;GO:0033327//Leydig cell differentiation;GO:0000245//spliceosomal complex assembly","K13095//splicing factor 1","NP_973726.2//splicing factor 1 isoform 4 [Homo sapiens];EDL33241.1//splicing factor 1, isoform CRA_a, partial [Mus musculus];NP_001171501.1//splicing factor 1 isoform 6 [Homo sapiens];XP_015333689.1//PREDICTED: splicing factor 1 isoform X4 [Marmota marmota marmota];NP_001333293.1//splicing factor 1 isoform 10 [Homo sapiens];NP_973724.1//splicing factor 1 isoform 2 [Homo sapiens];NP_001333292.1//splicing factor 1 isoform 9 [Homo sapiens];XP_015333691.1//PREDICTED: splicing factor 1 isoform X6 [Marmota marmota marmota];XP_012353274.1//PREDICTED: splicing factor 1 isoform X2 [Nomascus leucogenys];EDL33242.1//splicing factor 1, isoform CRA_b, partial [Mus musculus]","1//3;3//A2MP1;2//1"]
[153527,1644,77.14,77.03,-0.00205872065158588,1.01640984512045,"*",0.985168,"ZMAT2","NA","GO:0008270//zinc ion binding;GO:0003676//nucleic acid binding","NA","K12848//U4/U6.U5 tri-snRNP component SNU23","XP_004420129.2//PREDICTED: zinc finger matrin-type protein 2 [Ceratotherium simum simum]","2//1"]
[56850,3052,7.75,7.74,-1.86274401718951E-3,1.01357163241286,"*",0.981148,"GRIPAP1","GO:0043231//intracellular membrane-bounded organelle;GO:0030425//dendrite;GO:0030424//axon;GO:0005654//nucleoplasm;GO:0072562//blood microparticle;GO:0030054//cell junction;GO:0098837//postsynaptic recycling endosome;GO:0055038//recycling endosome membrane;GO:0031901//early endosome membrane;GO:0005829//cytosol","NA","GO:1905244//regulation of modification of synaptic structure;GO:0098887//neurotransmitter receptor transport, endosome to postsynaptic membrane","K18626//trichohyalin","NP_064522.3//GRIP1-associated protein 1 [Homo sapiens]",4]
[54433,1235,17.1,17.08,-0.00168835015277009,0.981878631421706,"*",0.946412,"GAR1","GO:0019013//viral nucleocapsid;GO:0031429//box H/ACA snoRNP complex","GO:0003723//RNA binding","GO:0006364//rRNA processing;GO:0001522//pseudouridine synthesis","K11128//H/ACA ribonucleoprotein complex subunit 1","XP_009446402.2//PREDICTED: H/ACA ribonucleoprotein complex subunit 1 [Pan troglodytes]","3//A2MP1;2//1"]
[9368,2032,38.9,38.86,-0.00148425428820965,1.0152025016152,"*",0.98368,"SLC9A3R1","GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0031526//brush border membrane;GO:0071944//cell periphery;GO:0031982//vesicle;GO:0005737//cytoplasm;GO:0012505//endomembrane system;GO:0015629//actin cytoskeleton;GO:0070062//extracellular exosome;GO:0032426//stereocilium tip;GO:0005902//microvillus;GO:0030175//filopodium;GO:0048471//perinuclear region of cytoplasm;GO:0001726//ruffle;GO:0045121//membrane raft;GO:0097225//sperm midpiece;GO:0031528//microvillus membrane","GO:0032947//protein complex scaffold activity;GO:0045159//myosin II binding;GO:0005102//receptor binding;GO:0043621//protein self-association;GO:0070851//growth factor receptor binding;GO:0031698//beta-2 adrenergic receptor binding;GO:0019902//phosphatase binding;GO:0030165//PDZ domain binding;GO:0008013//beta-catenin binding;GO:0017081//chloride channel regulator activity;GO:0050780//dopamine receptor binding;GO:0032403//protein complex binding","GO:0045859//regulation of protein kinase activity;GO:0030643//cellular phosphate ion homeostasis;GO:0070293//renal absorption;GO:0097291//renal phosphate ion absorption;GO:0034635//glutathione transport;GO:0051898//negative regulation of protein kinase B signaling;GO:0007097//nuclear migration;GO:0008285//negative regulation of cell proliferation;GO:0032782//bile acid secretion;GO:0030036//actin cytoskeleton organization;GO:0045930//negative regulation of mitotic cell cycle;GO:0008361//regulation of cell size;GO:0003096//renal sodium ion transport;GO:0008360//regulation of cell shape;GO:0030033//microvillus assembly;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0035414//negative regulation of catenin import into nucleus;GO:0016055//Wnt signaling pathway;GO:0014067//negative regulation of phosphatidylinositol 3-kinase signaling;GO:0006461//protein complex assembly;GO:0060088//auditory receptor cell stereocilium organization;GO:0044062//regulation of excretion;GO:0010642//negative regulation of platelet-derived growth factor receptor signaling pathway;GO:0007191//adenylate cyclase-activating dopamine receptor signaling pathway;GO:0051683//establishment of Golgi localization;GO:0045198//establishment of epithelial cell apical/basal polarity;GO:0072659//protein localization to plasma membrane;GO:0032415//regulation of sodium:proton antiporter activity;GO:0030336//negative regulation of cell migration;GO:0032416//negative regulation of sodium:proton antiporter activity;GO:0060158//phospholipase C-activating dopamine receptor signaling pathway;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway;GO:0007605//sensory perception of sound;GO:0022612//gland morphogenesis","K13365//Na(+)/H(+) exchange regulatory cofactor NHE-RF1","AAH49220.1//SLC9A3R1 protein, partial [Homo sapiens]",4]
[91949,2943,10.51,10.5,-1.37334140869342E-3,1.02206630106973,"*",0.99289,"COG7","GO:0032588//trans-Golgi network membrane;GO:0005730//nucleolus;GO:0017119//Golgi transport complex;GO:0005794//Golgi apparatus;GO:0000139//Golgi membrane","NA","GO:0006486//protein glycosylation;GO:0034067//protein localization to Golgi apparatus;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0007030//Golgi organization;GO:0006886//intracellular protein transport;GO:0033365//protein localization to organelle;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0050821//protein stabilization","K20294//conserved oligomeric Golgi complex subunit 7","NP_705831.1//conserved oligomeric Golgi complex subunit 7 [Homo sapiens]","3//A2MP1"]
[90557,1708,10.62,10.61,-0.00135910988938885,0.857857144847367,"*",0.786378,"CCDC74A","NA","NA","NA","K17776//metaxin;K13172//serine/arginine repetitive matrix protein 2","NP_001245235.1//coiled-coil domain-containing protein 74A isoform 4 [Homo sapiens];NP_001245233.1//coiled-coil domain-containing protein 74A isoform 2 [Homo sapiens];NP_001335976.1//coiled-coil domain-containing protein 74A isoform 11 [Homo sapiens];NP_001335975.1//coiled-coil domain-containing protein 74A isoform 10 [Homo sapiens];NP_001335972.1//coiled-coil domain-containing protein 74A isoform 7 [Homo sapiens];NP_001335971.1//coiled-coil domain-containing protein 74A isoform 6 [Homo sapiens];NP_001335974.1//coiled-coil domain-containing protein 74A isoform 9 [Homo sapiens];NP_620125.1//coiled-coil domain-containing protein 74A isoform 1 [Homo sapiens];NP_001335970.1//coiled-coil domain-containing protein 74A isoform 5 [Homo sapiens];NP_001335973.1//coiled-coil domain-containing protein 74A isoform 8 [Homo sapiens];NP_001245234.1//coiled-coil domain-containing protein 74A isoform 3 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[348235,2994,37.03,37,-0.00116927876795536,1.01283074160792,"*",0.980304,"SKA2","GO:0005829//cytosol;GO:0000940//condensed chromosome outer kinetochore;GO:0005737//cytoplasm;GO:0005876//spindle microtubule","GO:0008017//microtubule binding","GO:0000278//mitotic cell cycle;GO:0007059//chromosome segregation;GO:0007062//sister chromatid cohesion;GO:0031110//regulation of microtubule polymerization or depolymerization;GO:0051301//cell division","K12581//CCR4-NOT transcription complex subunit 7/8;K01064//wingless-type MMTV integration site family, member 9","NP_001094065.1//spindle and kinetochore-associated protein 2 isoform 2 [Homo sapiens];NP_001317328.1//spindle and kinetochore-associated protein 2 isoform 3 [Homo sapiens];NP_872426.1//spindle and kinetochore-associated protein 2 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[79017,1197,37.99,37.96,-0.00113971964391311,0.697317674481515,"*",0.580938,"GGCT","GO:0070062//extracellular exosome;GO:0005829//cytosol","GO:0003839//gamma-glutamylcyclotransferase activity;GO:0042803//protein homodimerization activity","GO:0006750//glutathione biosynthetic process;GO:0001836//release of cytochrome c from mitochondria","K00682//gamma-glutamylcyclotransferase [EC:4.3.2.9]","NP_001186744.1//gamma-glutamylcyclotransferase isoform 2 [Homo sapiens];NP_001186745.1//gamma-glutamylcyclotransferase isoform 3 [Homo sapiens];NP_001186746.1//gamma-glutamylcyclotransferase isoform 4 [Homo sapiens];NP_076956.1//gamma-glutamylcyclotransferase isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[55761,4184,16.65,16.64,-0.000866743817532217,0.986900616162926,"*",0.95255,"TTC17","GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0005886//plasma membrane;GO:0005737//cytoplasm","NA","GO:0044782//cilium organization;GO:0030041//actin filament polymerization","NA","NP_060729.2//tetratricopeptide repeat protein 17 isoform 1 [Homo sapiens];NP_001294872.1//tetratricopeptide repeat protein 17 isoform 2 [Homo sapiens]","1//3;5"]
[221545,1479,18.58,18.57,-0.000776686447231918,0.992986829401089,"*",0.959046,"C6orf136","GO:0005739//mitochondrion","NA","NA","K03006//DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6];K05853//Ca2+ transporting ATPase, sarcoplasmic/endoplasmic reticulum [EC:3.6.3.8];K21125//mucin-5AC","NP_001103408.1//uncharacterized protein C6orf136 isoform 1 [Homo sapiens];NP_659466.2//uncharacterized protein C6orf136 isoform 2 [Homo sapiens];XP_003897351.2//LOW QUALITY PROTEIN: uncharacterized protein C6orf136 homolog [Papio anubis]","1//3;3//A2MP1;2//1"]
[83637,5063,21.86,21.85,-0.000660121283943764,1.00757072587222,"*",0.974456,"ZMIZ2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0043596//nuclear replication fork","GO:0008270//zinc ion binding;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity","GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated","K00164//2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2];K16064//E3 SUMO-protein ligase PIAS3;K04706//E3 SUMO-protein ligase PIAS1;K06794//neurocan core protein","NP_113637.3//zinc finger MIZ domain-containing protein 2 isoform 1 [Homo sapiens];NP_777589.2//zinc finger MIZ domain-containing protein 2 isoform 2 [Homo sapiens];NP_001287888.1//zinc finger MIZ domain-containing protein 2 isoform 3 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[64841,3945,23.35,23.34,-0.000617988889676312,0.996584239243131,"*",0.96277,"GNPNAT1","NA","NA","NA","K00621//glucosamine-phosphate N-acetyltransferase [EC:2.3.1.4]","XP_017704960.1//PREDICTED: glucosamine 6-phosphate N-acetyltransferase isoform X1 [Rhinopithecus bieti]","3//A2MP1"]
[27044,3678,62.59,62.57,-0.000461072244540993,0.977936301287889,"*",0.941204,"SND1","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0042470//melanosome;GO:0005737//cytoplasm;GO:0097433//dense body;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0016442//RISC complex","GO:0003723//RNA binding;GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0004518//nuclease activity;GO:0045296//cadherin binding","GO:0006401//RNA catabolic process;GO:0001649//osteoblast differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0031047//gene silencing by RNA;GO:0016032//viral process","K15979//staphylococcal nuclease domain-containing protein 1","BAD92747.1//EBNA-2 co-activator variant, partial [Homo sapiens]","3//A2MP1"]
[79833,705,33.91,33.9,-4.25511001724551E-4,1.01387024481086,"*",0.981564,"GEMIN6","GO:0034719//SMN-Sm protein complex;GO:0032797//SMN complex;GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0097504//Gemini of coiled bodies;GO:0005829//cytosol;GO:0005737//cytoplasm","NA","GO:0000398//mRNA splicing, via spliceosome;GO:0051170//nuclear import;GO:0000245//spliceosomal complex assembly;GO:0000387//spliceosomal snRNP assembly","K13134//gem associated protein 6","NP_079051.9//gem-associated protein 6 [Homo sapiens]","9//1"]
[29098,936,42.7,42.69,-0.00033790726021438,0.792420472182999,"*",0.702632,"RANGRF","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005791//rough endoplasmic reticulum;GO:0005737//cytoplasm;GO:0005901//caveola;GO:0005829//cytosol;GO:0014704//intercalated disc;GO:0005886//plasma membrane","GO:0005087//Ran guanyl-nucleotide exchange factor activity;GO:0044325//ion channel binding;GO:0008536//Ran GTPase binding;GO:0017080//sodium channel regulator activity;GO:0008565//protein transporter activity;GO:0005085//guanyl-nucleotide exchange factor activity","GO:0032527//protein exit from endoplasmic reticulum;GO:0098909//regulation of cardiac muscle cell action potential involved in regulation of contraction;GO:2000010//positive regulation of protein localization to cell surface;GO:0043547//positive regulation of GTPase activity;GO:0002027//regulation of heart rate;GO:0098905//regulation of bundle of His cell action potential;GO:2000649//regulation of sodium ion transmembrane transporter activity;GO:1902305//regulation of sodium ion transmembrane transport;GO:0003254//regulation of membrane depolarization;GO:1903078//positive regulation of protein localization to plasma membrane;GO:0006888//ER to Golgi vesicle-mediated transport;GO:1900825//regulation of membrane depolarization during cardiac muscle cell action potential;GO:0042391//regulation of membrane potential","K17495//CUB and sushi domain-containing protein;K15117//solute carrier family 25, member 34/35","NP_001171273.1//ran guanine nucleotide release factor isoform C [Homo sapiens];NP_001317056.1//ran guanine nucleotide release factor isoform D [Homo sapiens];NP_057576.2//ran guanine nucleotide release factor isoform A [Homo sapiens]","4;1//3"]
[9550,1611,46.18,46.17,-0.000312440724748762,1.00033928777771,"*",0.966836,"ATP6V1G1","GO:0005765//lysosomal membrane;GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0016471//vacuolar proton-transporting V-type ATPase complex;GO:0005886//plasma membrane","GO:0008553//hydrogen-exporting ATPase activity, phosphorylative mechanism;GO:0051117//ATPase binding","GO:0016241//regulation of macroautophagy;GO:0006879//cellular iron ion homeostasis;GO:0008286//insulin receptor signaling pathway;GO:0034220//ion transmembrane transport;GO:0033572//transferrin transport;GO:0036295//cellular response to increased oxygen levels;GO:0090383//phagosome acidification;GO:0015992//proton transport","K02152//V-type H+-transporting ATPase subunit G","NP_004879.1//V-type proton ATPase subunit G 1 [Homo sapiens]","3//A2MP1"]
[6009,2092,66.93,66.92,-2.15568926944165E-4,0.988517357800545,"*",0.954358,"RHEB","GO:0030425//dendrite;GO:0016020//membrane;GO:0005765//lysosomal membrane;GO:0070062//extracellular exosome;GO:0043025//neuronal cell body;GO:0000139//Golgi membrane;GO:0005681//spliceosomal complex;GO:0005829//cytosol;GO:0005789//endoplasmic reticulum membrane","GO:0000287//magnesium ion binding;GO:0019003//GDP binding;GO:0005525//GTP binding;GO:0019901//protein kinase binding;GO:0003924//GTPase activity","GO:0016241//regulation of macroautophagy;GO:0032006//regulation of TOR signaling;GO:0007165//signal transduction;GO:0048714//positive regulation of oligodendrocyte differentiation;GO:0032008//positive regulation of TOR signaling;GO:0007050//cell cycle arrest;GO:2000074//regulation of type B pancreatic cell development;GO:0048168//regulation of neuronal synaptic plasticity;GO:0007264//small GTPase mediated signal transduction","K07208//Ras homolog enriched in brain","NP_005605.1//GTP-binding protein Rheb [Homo sapiens]","3//A2MP1"]

{"sheet":"A549-VS-A549_plus_INF_r.Pos (2","index":1,"n_rows":15975,"n_cols":15,"rows_kept":4500,"cut":true,"bounds":{"rows_first":2000,"rows_last":500,"rows_between":2000,"halvings":0}}
["GeneID","Length","A549-Expression","A549_plus_INF_r-Expression","log2FoldChange(A549_plus_INF_r/A549)","FDR","Up/Down-Regulation(A549_plus_INF_r/A549)","Pvalue","Symbol","Cellular Component","Molecular Function","Biological Process","Kegg Orthology","Nr Description","Desc"]
[875,2583,0.01,8.81,9.78299820892041,{"v":1.63674973411765E-84,"d":"1.64E-84"},"Up",{"v":1.219314E-86,"d":"1.22E-86"},"CBS","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0020037//heme binding;GO:0072341//modified amino acid binding;GO:0042802//identical protein binding;GO:0031625//ubiquitin protein ligase binding;GO:1904047//S-adenosyl-L-methionine binding;GO:0070026//nitric oxide binding;GO:0042803//protein homodimerization activity;GO:0019825//oxygen binding;GO:0050421//nitrite reductase (NO-forming) activity;GO:0046872//metal ion binding;GO:0004122//cystathionine beta-synthase activity;GO:0070025//carbon monoxide binding;GO:0030170//pyridoxal phosphate binding;GO:0019899//enzyme binding","GO:0043418//homocysteine catabolic process;GO:0019346//transsulfuration;GO:0042262//DNA protection;GO:0006565//L-serine catabolic process;GO:0006563//L-serine metabolic process;GO:0019343//cysteine biosynthetic process via cystathionine;GO:0006535//cysteine biosynthetic process from serine;GO:0050667//homocysteine metabolic process;GO:0070814//hydrogen sulfide biosynthetic process;GO:0019344//cysteine biosynthetic process;GO:0019448//L-cysteine catabolic process","K01697//cystathionine beta-synthase [EC:4.2.1.22]","XP_009200453.1//cystathionine beta-synthase isoform X2 [Papio anubis];NP_001308001.1//cystathionine beta-synthase isoform 2 [Homo sapiens]","1//3;2//1"]
[54065,917,0.01,2.12,7.7279204545632,{"v":7.18055652489386e-07,"d":"7.18E-07"},"Up",{"v":1.164694E-7,"d":"1.16E-07"},"SMIM11A","NA","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K06245//laminin, beta 4;K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K01064//wingless-type MMTV integration site family, member 9","BAG64432.1//unnamed protein product [Homo sapiens]",4]
[30009,2589,0.01,1.91,7.57742882803575,{"v":3.68634383257919e-18,"d":"3.69E-18"},"Up",{"v":2.04002e-19,"d":"2.04E-19"},"TBX21","GO:0005634//nucleus;GO:0043025//neuronal cell body","GO:0043565//sequence-specific DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0001227//transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding","GO:0006355//regulation of transcription, DNA-templated;GO:0045580//regulation of T cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0071310//cellular response to organic substance;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0032703//negative regulation of interleukin-2 production;GO:2000552//negative regulation of T-helper 2 cell cytokine production;GO:0072676//lymphocyte migration;GO:0045892//negative regulation of transcription, DNA-templated;GO:2000329//negative regulation of T-helper 17 cell lineage commitment;GO:0006351//transcription, DNA-templated;GO:2000320//negative regulation of T-helper 17 cell differentiation;GO:0048304//positive regulation of isotype switching to IgG isotypes;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0007275//multicellular organism development;GO:0030217//T cell differentiation;GO:0009615//response to virus","K10166//T-box protein 21","NP_037483.1//T-box transcription factor TBX21 [Homo sapiens]","1//3"]
[10537,1006,0.01,1.88,7.55458885167764,{"v":7.18332894054054e-07,"d":"7.18E-07"},"Up",{"v":1.164694E-7,"d":"1.16E-07"},"UBD","GO:0005634//nucleus;GO:0005829//cytosol;GO:0016235//aggresome;GO:0001650//fibrillar center;GO:0005737//cytoplasm","GO:0070628//proteasome binding","GO:0043687//post-translational protein modification;GO:0016567//protein ubiquitination;GO:0032446//protein modification by small protein conjugation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:1901990//regulation of mitotic cell cycle phase transition;GO:0043065//positive regulation of apoptotic process;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006508//proteolysis;GO:0034612//response to tumor necrosis factor;GO:0034341//response to interferon-gamma;GO:0070842//aggresome assembly;GO:0043011//myeloid dendritic cell differentiation","K12157//ubiquitin D","NP_006389.2//ubiquitin D [Homo sapiens]","3//A2MP1"]
[375593,1358,0.01,1.73,7.43462822763673,{"v":1.39959159864407E-8,"d":"1.40E-08"},"Up",{"v":1.809288E-9,"d":"1.81E-09"},"TRIM73","GO:0005829//cytosol;GO:0005622//intracellular","GO:0008270//zinc ion binding","NA","K12024//tripartite motif-containing protein 50/73/74","NP_944606.2//tripartite motif-containing protein 73 [Homo sapiens]","3//A2MP1"]
[128653,631,0.01,1.48,7.20945336562895,0.00087267341128484,"Up",2.41086E-4,"C20orf141","GO:0016021//integral component of membrane","NA","NA","NA","NP_542777.1//uncharacterized protein C20orf141 [Homo sapiens]","1//3;2//1"]
[2633,3050,0.05,6.79,7.08533966935737,{"v":4.31300366518519e-73,"d":"4.31E-73"},"Up",{"v":3.64502e-75,"d":"3.65E-75"},"GBP1","GO:0005829//cytosol;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0000139//Golgi membrane","GO:0019955//cytokine binding;GO:0042802//identical protein binding;GO:0019003//GDP binding;GO:0042803//protein homodimerization activity;GO:0003924//GTPase activity;GO:0003779//actin binding;GO:0051879//Hsp90 protein binding;GO:0005525//GTP binding;GO:0019899//enzyme binding;GO:0030507//spectrin binding","GO:0060333//interferon-gamma-mediated signaling pathway;GO:1903077//negative regulation of protein localization to plasma membrane;GO:1900025//negative regulation of substrate adhesion-dependent cell spreading;GO:0051607//defense response to virus;GO:0051260//protein homooligomerization;GO:1900041//negative regulation of interleukin-2 secretion;GO:1903076//regulation of protein localization to plasma membrane;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0050860//negative regulation of T cell receptor signaling pathway;GO:0050848//regulation of calcium-mediated signaling","K20899//guanylate-binding protein 1/3/4/7","NP_002044.2//guanylate-binding protein 1 [Homo sapiens]","2//1"]
[29126,3083,0.05,5.95,6.89481776330794,{"v":1.63225608717949e-64,"d":"1.63E-64"},"Up",{"v":1.59404e-66,"d":"1.59E-66"},"CD274","GO:0070062//extracellular exosome;GO:0012505//endomembrane system;GO:0009897//external side of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","NA","GO:0046007//negative regulation of activated T cell proliferation;GO:0007165//signal transduction;GO:0030335//positive regulation of cell migration;GO:0032693//negative regulation of interleukin-10 production;GO:0034097//response to cytokine;GO:0042102//positive regulation of T cell proliferation;GO:0007166//cell surface receptor signaling pathway;GO:0031295//T cell costimulation;GO:1903556//negative regulation of tumor necrosis factor superfamily cytokine production;GO:1901998//toxin transport;GO:1905404//positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process;GO:0006955//immune response;GO:0032689//negative regulation of interferon-gamma production;GO:2001181//positive regulation of interleukin-10 secretion","K06745//programmed cell death 1 ligand 1","NP_054862.1//programmed cell death 1 ligand 1 isoform a precursor [Homo sapiens];NP_001300958.1//programmed cell death 1 ligand 1 isoform c precursor [Homo sapiens];NP_001254635.1//programmed cell death 1 ligand 1 isoform b precursor [Homo sapiens]","1//3;3//A2MP1"]
[101060321,2090,0.01,0.86,6.4262647547021,{"v":1.37640862379897e-06,"d":"1.38E-06"},"Up",{"v":2.33164e-07,"d":"2.33E-07"},"TBC1D3G","GO:0012505//endomembrane system;GO:0005622//intracellular;GO:0005886//plasma membrane","GO:0017137//Rab GTPase binding;GO:0005096//GTPase activator activity","GO:0006886//intracellular protein transport;GO:0090630//activation of GTPase activity;GO:0031338//regulation of vesicle fusion","K20134//TBC1 domain family member 3","NP_001278391.1//TBC1 domain family member 3G [Homo sapiens]","1//3"]
[3702,4366,0.01,0.83,6.37503943134693,{"v":1.74216421461847e-13,"d":"1.74E-13"},"Up",{"v":1.357828e-14,"d":"1.36E-14"},"ITK","GO:0005634//nucleus;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0005829//cytosol;GO:0005911//cell-cell junction","GO:0046872//metal ion binding;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005524//ATP binding","GO:0042110//T cell activation;GO:0007165//signal transduction;GO:0038083//peptidyl-tyrosine autophosphorylation;GO:0050852//T cell receptor signaling pathway;GO:0042127//regulation of cell proliferation;GO:0035556//intracellular signal transduction;GO:0032609//interferon-gamma production;GO:0001816//cytokine production;GO:0006968//cellular defense response;GO:0002250//adaptive immune response;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0001865//NK T cell differentiation;GO:0007202//activation of phospholipase C activity;GO:0032633//interleukin-4 production;GO:0045087//innate immune response","K07363//IL2-inducible T-cell kinase [EC:2.7.10.2]","NP_005537.3//tyrosine-protein kinase ITK/TSK [Homo sapiens]","3//A2MP1"]
[3627,1227,0.01,0.8,6.32192809488736,0.0008720805625,"Up",2.41086E-4,"CXCL10","GO:0005615//extracellular space;GO:0009897//external side of plasma membrane;GO:0005623//cell;GO:0005576//extracellular region","GO:0048248//CXCR3 chemokine receptor binding;GO:0008603//cAMP-dependent protein kinase regulator activity;GO:0008201//heparin binding;GO:0005102//receptor binding;GO:0008009//chemokine activity","GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0042127//regulation of cell proliferation;GO:0071222//cellular response to lipopolysaccharide;GO:0007166//cell surface receptor signaling pathway;GO:0010332//response to gamma radiation;GO:2000406//positive regulation of T cell migration;GO:0043950//positive regulation of cAMP-mediated signaling;GO:0007165//signal transduction;GO:0010996//response to auditory stimulus;GO:0090026//positive regulation of monocyte chemotaxis;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0070098//chemokine-mediated signaling pathway;GO:0031640//killing of cells of other organism;GO:0033280//response to vitamin D;GO:0008015//blood circulation;GO:0045662//negative regulation of myoblast differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0010819//regulation of T cell chemotaxis;GO:1901740//negative regulation of myoblast fusion;GO:0032496//response to lipopolysaccharide;GO:0030816//positive regulation of cAMP metabolic process;GO:0010818//T cell chemotaxis;GO:0006935//chemotaxis;GO:0007186//G-protein coupled receptor signaling pathway;GO:0016525//negative regulation of angiogenesis;GO:0009409//response to cold;GO:0051607//defense response to virus;GO:0007267//cell-cell signaling;GO:0007517//muscle organ development;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0034605//cellular response to heat;GO:0006954//inflammatory response;GO:1901509//regulation of endothelial tube morphogenesis;GO:0006952//defense response;GO:0006955//immune response;GO:0042118//endothelial cell activation;GO:0008284//positive regulation of cell proliferation","K12671//C-X-C motif chemokine 10","NP_001556.2//C-X-C motif chemokine 10 precursor [Homo sapiens]","3//A2MP1"]
[729262,3292,0.01,0.75,6.22881869049588,{"v":7.26196681690141e-09,"d":"7.26E-09"},"Up",{"v":9.03768e-10,"d":"9.04E-10"},"NUTM2B","NA","NA","NA","K17602//YLP motif-containing protein 1;K13911//basic salivary proline-rich protein 1/2","NP_001265424.1//NUT family member 2B [Homo sapiens]","1//3"]
[2944,1266,0.01,0.73,6.18982455888002,0.00165514371232289,"*",0.000482638,"GSTM1","NA","NA","NA","K00799//glutathione S-transferase [EC:2.5.1.18]","XP_009244998.1//PREDICTED: glutathione S-transferase Mu 1 isoform X1 [Pongo abelii]","3//A2MP1;2//1"]
[684,1048,0.01,0.71,6.14974711950468,5.90904806961178E-3,"*",1.934294E-3,"BST2","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0016324//apical plasma membrane;GO:0031225//anchored component of membrane;GO:0035577//azurophil granule membrane;GO:0009986//cell surface;GO:0045121//membrane raft;GO:0005887//integral component of plasma membrane;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005771//multivesicular body;GO:0005886//plasma membrane","GO:0003723//RNA binding;GO:0008191//metalloendopeptidase inhibitor activity;GO:0042802//identical protein binding;GO:0004871//signal transducer activity;GO:0042803//protein homodimerization activity","GO:0035456//response to interferon-beta;GO:0060337//type I interferon signaling pathway;GO:0032956//regulation of actin cytoskeleton organization;GO:0008283//cell proliferation;GO:0006959//humoral immune response;GO:0034341//response to interferon-gamma;GO:0045071//negative regulation of viral genome replication;GO:1901253//negative regulation of intracellular transport of viral material;GO:0043312//neutrophil degranulation;GO:0045087//innate immune response;GO:0030308//negative regulation of cell growth;GO:0007267//cell-cell signaling;GO:0051607//defense response to virus;GO:0030336//negative regulation of cell migration;GO:0002737//negative regulation of plasmacytoid dendritic cell cytokine production;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0035455//response to interferon-alpha;GO:0007275//multicellular organism development;GO:0009615//response to virus;GO:0042113//B cell activation","K06731//bone marrow stromal cell antigen 2","NP_004326.1//bone marrow stromal antigen 2 precursor [Homo sapiens]","3//A2MP1"]
[121793,859,0.01,0.66,6.04439411935845,0.0379992175965665,"*",0.0155194,"TEX29","GO:0016021//integral component of membrane","NA","NA","NA","XP_016875876.1//PREDICTED: testis-expressed sequence 29 protein isoform X1 [Homo sapiens];NP_001290062.1//testis-expressed protein 29 isoform 1 [Homo sapiens]","1//3;2//1"]
[733,888,0.01,0.65,6.02236781302845,0.0205874186733167,"*",7.75218E-3,"C8G","NA","NA","NA","K03999//complement component 8 subunit gamma","XP_016817690.1//PREDICTED: complement component C8 gamma chain [Pan troglodytes]","2//1"]
[100293534,5427,0.01,0.61,5.93073733756289,{"v":4.96403703629893e-12,"d":"4.96E-12"},"Up",{"v":4.36614e-13,"d":"4.37E-13"},"C4B_2","GO:0070062//extracellular exosome;GO:0005788//endoplasmic reticulum lumen;GO:0030425//dendrite;GO:0030424//axon;GO:0005615//extracellular space;GO:0072562//blood microparticle;GO:0044216//other organism cell;GO:0030054//cell junction;GO:0043025//neuronal cell body;GO:0005576//extracellular region;GO:0045202//synapse;GO:0005886//plasma membrane","GO:0001848//complement binding;GO:0004252//serine-type endopeptidase activity;GO:0030246//carbohydrate binding;GO:0004866//endopeptidase inhibitor activity;GO:0001849//complement component C1q binding","GO:0043687//post-translational protein modification;GO:0030449//regulation of complement activation;GO:0006956//complement activation;GO:0032490//detection of molecule of bacterial origin;GO:0006954//inflammatory response;GO:0044267//cellular protein metabolic process;GO:0006958//complement activation, classical pathway;GO:2000427//positive regulation of apoptotic cell clearance;GO:0045087//innate immune response;GO:0008228//opsonization","K03989//complement component 4","NP_001229752.1//complement C4-B-like preproprotein [Homo sapiens]","2//1"]
[653604,457,0.01,0.58,5.85798099512757,0.226747397218422,"*",0.1245166,"HIST2H3D","NA","NA","NA","K11253//histone H3","XP_012669845.1//PREDICTED: uncharacterized protein LOC105888650 [Clupea harengus]","2//1"]
[5196,878,0.01,0.57,5.83289001416474,0.0380050430170167,"*",0.0155194,"PF4","GO:0031093//platelet alpha granule lumen;GO:0005615//extracellular space;GO:0020005//symbiont-containing vacuole membrane;GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0097679//other organism cytoplasm","GO:0048248//CXCR3 chemokine receptor binding;GO:0045236//CXCR chemokine receptor binding;GO:0008201//heparin binding;GO:0008009//chemokine activity","GO:0010744//positive regulation of macrophage derived foam cell differentiation;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0045347//negative regulation of MHC class II biosynthetic process;GO:0042127//regulation of cell proliferation;GO:0032496//response to lipopolysaccharide;GO:0030168//platelet activation;GO:0030816//positive regulation of cAMP metabolic process;GO:0051873//killing by host of symbiont cells;GO:0032760//positive regulation of tumor necrosis factor production;GO:0002576//platelet degranulation;GO:0045653//negative regulation of megakaryocyte differentiation;GO:0045651//positive regulation of macrophage differentiation;GO:0043950//positive regulation of cAMP-mediated signaling;GO:0007186//G-protein coupled receptor signaling pathway;GO:0090023//positive regulation of neutrophil chemotaxis;GO:0042832//defense response to protozoan;GO:0016525//negative regulation of angiogenesis;GO:0070098//chemokine-mediated signaling pathway;GO:0030595//leukocyte chemotaxis;GO:0031640//killing of cells of other organism;GO:0045652//regulation of megakaryocyte differentiation;GO:0010628//positive regulation of gene expression;GO:0006954//inflammatory response;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006955//immune response;GO:0019221//cytokine-mediated signaling pathway;GO:0045918//negative regulation of cytolysis","K05407//platelet factor 4","XP_003265787.1//PREDICTED: platelet factor 4 [Nomascus leucogenys]","3//A2MP1"]
[8968,466,0.01,0.56,5.8073549220576,0.226876715911943,"*",0.1245166,"HIST1H3F","GO:0005634//nucleus;GO:0000786//nucleosome","GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity","GO:0006334//nucleosome assembly;GO:0006352//DNA-templated transcription, initiation","K11253//histone H3","XP_012890639.1//PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein LOC106000001 [Dipodomys ordii]","2//1"]
[100529251,794,0.01,0.56,5.8073549220576,0.0702168946236559,"*",0.0310688,"CKLF-CMTM1","GO:0016021//integral component of membrane","NA","NA","NA","NP_001189438.1//CKLF-CMTM1 protein isoform 3 [Homo sapiens];NP_001191027.1//CKLF-CMTM1 protein isoform 2 [Homo sapiens];NP_001191028.1//CKLF-CMTM1 protein isoform 1 [Homo sapiens]","1//3"]
[84648,617,0.01,0.55,5.78135971352466,0.127558204134035,"*",0.062198,"LCE3D","GO:0005829//cytosol;GO:0001533//cornified envelope;GO:0005737//cytoplasm","GO:0005198//structural molecule activity","GO:0018149//peptide cross-linking;GO:0030216//keratinocyte differentiation;GO:0070268//cornification","NA","NP_115952.1//late cornified envelope protein 3D [Homo sapiens]","1//3"]
[3394,2678,0.06,3.22,5.74595437739346,{"v":1.48962552656587e-28,"d":"1.49E-28"},"Up",{"v":4.31762e-30,"d":"4.32E-30"},"IRF8","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003705//transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0060337//type I interferon signaling pathway;GO:0042832//defense response to protozoan;GO:0030099//myeloid cell differentiation;GO:0071222//cellular response to lipopolysaccharide;GO:0006351//transcription, DNA-templated;GO:0042742//defense response to bacterium;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0071346//cellular response to interferon-gamma;GO:0032735//positive regulation of interleukin-12 production;GO:0044130//negative regulation of growth of symbiont in host;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006955//immune response;GO:0032729//positive regulation of interferon-gamma production;GO:0006909//phagocytosis","K10155//interferon regulatory factor 8","XP_017716051.1//PREDICTED: interferon regulatory factor 8 [Rhinopithecus bieti]","2//1"]
[54567,3420,0.02,0.88,5.4594316186373,{"v":6.51646728490352e-10,"d":"6.52E-10"},"Up",{"v":7.18794e-11,"d":"7.19E-11"},"DLL4","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005509//calcium ion binding;GO:0005112//Notch binding","GO:0003222//ventricular trabecula myocardium morphogenesis;GO:0090051//negative regulation of cell migration involved in sprouting angiogenesis;GO:0003209//cardiac atrium morphogenesis;GO:0072554//blood vessel lumenization;GO:0045747//positive regulation of Notch signaling pathway;GO:0003344//pericardium morphogenesis;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0007601//visual perception;GO:0010629//negative regulation of gene expression;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0061074//regulation of neural retina development;GO:0060579//ventral spinal cord interneuron fate commitment;GO:0061314//Notch signaling involved in heart development;GO:0008285//negative regulation of cell proliferation;GO:1903588//negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis;GO:0007165//signal transduction;GO:0001525//angiogenesis;GO:0035912//dorsal aorta morphogenesis;GO:0010596//negative regulation of endothelial cell migration;GO:0010628//positive regulation of gene expression;GO:0003208//cardiac ventricle morphogenesis;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:2000179//positive regulation of neural precursor cell proliferation;GO:0001974//blood vessel remodeling;GO:0008015//blood circulation;GO:0007220//Notch receptor processing;GO:0045746//negative regulation of Notch signaling pathway;GO:0030217//T cell differentiation;GO:0007219//Notch signaling pathway;GO:0001569//branching involved in blood vessel morphogenesis;GO:0050767//regulation of neurogenesis","K06051//delta","EAW92466.1//delta-like 4 (Drosophila) [Homo sapiens]","3//A2MP1"]
[390940,938,0.01,0.43,5.4262647547021,0.226308814245079,"*",0.1245166,"PINLYP","GO:0005576//extracellular region","GO:0004859//phospholipase inhibitor activity","NA","K03985//plasminogen activator, urokinase receptor","NP_001180550.1//phospholipase A2 inhibitor and Ly6/PLAUR domain-containing protein isoform 1 [Homo sapiens];A6NC86.3//RecName: Full=phospholipase A2 inhibitor and Ly6/PLAUR domain-containing protein; Flags: Precursor;AAC99796.1//R28379_1, partial [Homo sapiens]","1//3"]
[51463,2217,0.01,0.42,5.39231742277876,0.00165549912218166,"*",0.000482638,"GPR89B","GO:0032580//Golgi cisterna membrane;GO:0016021//integral component of membrane;GO:0030660//Golgi-associated vesicle membrane","GO:0008308//voltage-gated anion channel activity;GO:0004871//signal transducer activity","GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043588//skin development;GO:0051452//intracellular pH reduction;GO:0015031//protein transport","K22193//golgi pH regulator","NP_057418.1//Golgi pH regulator B isoform 1 [Homo sapiens];XP_007975517.1//PREDICTED: Golgi pH regulator A isoform X2 [Chlorocebus sabaeus]","4;1//3"]
[6354,815,0.01,0.41,5.35755200461808,0.127672944230275,"*",0.062198,"CCL7","GO:0005615//extracellular space","GO:0031727//CCR2 chemokine receptor binding;GO:0008009//chemokine activity;GO:0031726//CCR1 chemokine receptor binding;GO:0048020//CCR chemokine receptor binding","GO:0043547//positive regulation of GTPase activity;GO:0071356//cellular response to tumor necrosis factor;GO:0071346//cellular response to interferon-gamma;GO:0071347//cellular response to interleukin-1;GO:0002548//monocyte chemotaxis;GO:0007186//G-protein coupled receptor signaling pathway;GO:0048247//lymphocyte chemotaxis;GO:0048245//eosinophil chemotaxis;GO:2000503//positive regulation of natural killer cell chemotaxis;GO:0030593//neutrophil chemotaxis;GO:0070098//chemokine-mediated signaling pathway;GO:0008360//regulation of cell shape;GO:0006954//inflammatory response;GO:0007010//cytoskeleton organization;GO:0006955//immune response;GO:0070374//positive regulation of ERK1 and ERK2 cascade","K05509//C-C motif chemokine 7","XP_003818055.1//PREDICTED: C-C motif chemokine 7 [Pan paniscus]","3//A2MP1"]
[6019,619,0.01,0.41,5.35755200461808,0.226644048359161,"*",0.1245166,"RLN2","GO:0005576//extracellular region","GO:0005179//hormone activity","GO:0007565//female pregnancy;GO:0045766//positive regulation of angiogenesis;GO:0050790//regulation of catalytic activity;GO:0010628//positive regulation of gene expression;GO:0030819//positive regulation of cAMP biosynthetic process","K21998//relaxin 1/2","NP_005050.2//prorelaxin H2 isoform 2 precursor [Homo sapiens];NP_604390.1//prorelaxin H2 isoform 1 preproprotein [Homo sapiens]","1//3;3//A2MP1;2//1"]
[3383,3249,1.06,42.59,5.32837855998714,0,"Up",0,"ICAM1","GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0005925//focal adhesion;GO:0009897//external side of plasma membrane;GO:0001772//immunological synapse;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0045121//membrane raft;GO:0016021//integral component of membrane","GO:0005178//integrin binding;GO:0004872//receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0001618//virus receptor activity","GO:0007159//leukocyte cell-cell adhesion;GO:0033627//cell adhesion mediated by integrin;GO:0002291//T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell;GO:1900027//regulation of ruffle assembly;GO:0002693//positive regulation of cellular extravasation;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0030155//regulation of cell adhesion;GO:0002457//T cell antigen processing and presentation;GO:0050900//leukocyte migration;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:0071333//cellular response to glucose stimulus;GO:1990830//cellular response to leukemia inhibitory factor;GO:0007155//cell adhesion;GO:0044406//adhesion of symbiont to host;GO:0022614//membrane to membrane docking;GO:0061028//establishment of endothelial barrier;GO:0002438//acute inflammatory response to antigenic stimulus;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0046813//receptor-mediated virion attachment to host cell","K06490//intercellular adhesion molecule 1","NP_000192.2//intercellular adhesion molecule 1 precursor [Homo sapiens]","2//1"]
[432355,593,0.01,0.4,5.32192809488736,0.392731322221126,"*",0.249274,"SLURP2","GO:0005615//extracellular space","GO:0033130//acetylcholine receptor binding;GO:0030548//acetylcholine receptor regulator activity","GO:0099601//regulation of neurotransmitter receptor activity;GO:0095500//acetylcholine receptor signaling pathway","K13909//mucin-7","NP_803253.1//ly-6/neurotoxin-like protein 1 isoform b precursor [Homo sapiens]","1//3;2//1"]
[116071,1991,0.78,30.44,5.2863504246413,{"v":1.65392916705882e-194,"d":"1.65E-194"},"Up",{"v":3.52032e-197,"d":"3.52E-197"},"BATF2","GO:0005634//nucleus","GO:0003677//DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0042832//defense response to protozoan;GO:0006351//transcription, DNA-templated;GO:0043011//myeloid dendritic cell differentiation","K09034//ATF-like basic leucine zipper transcriptional factor","NP_001287736.1//basic leucine zipper transcriptional factor ATF-like 2 isoform 2 [Homo sapiens];EAW74331.1//basic leucine zipper transcription factor, ATF-like 2, isoform CRA_b [Homo sapiens];NP_612465.3//basic leucine zipper transcriptional factor ATF-like 2 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[163688,1101,0.01,0.39,5.28540221886225,0.0702367692046419,"*",0.0310688,"CALML6","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0005509//calcium ion binding","NA","K02183//calmodulin","NP_619650.2//calmodulin-like protein 6 isoform 1 [Homo sapiens];XP_011282712.2//PREDICTED: calmodulin-like protein 6, partial [Felis catus]","1//3;3//A2MP1"]
[349334,1251,0.01,0.38,5.24792751344359,0.0702765521382045,"*",0.0310688,"FOXD4L4","GO:0005634//nucleus","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding","GO:0009653//anatomical structure morphogenesis;GO:0030154//cell differentiation;GO:0006351//transcription, DNA-templated","K09397//forkhead box protein D","NP_954714.2//forkhead box protein D4-like 4 [Homo sapiens]","3//A2MP1"]
[388394,1110,0.01,0.37,5.20945336562895,0.0702865049143181,"*",0.0310688,"RPRML","GO:0016021//integral component of membrane","NA","NA","K10128//reprimo, TP53-dependent G2 arrest mediator candidate","XP_021784073.1//reprimo-like protein [Papio anubis]",4]
[100131187,564,0.01,0.37,5.20945336562895,0.226180141960428,"*",0.1245166,"TSTD1","NA","NA","NA","K06089//junctional adhesion molecule 1;K01011//thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]","XP_003780801.1//PREDICTED: LOW QUALITY PROTEIN: thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 1 [Pongo abelii];XP_003308600.1//PREDICTED: thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 1 isoform X1 [Pan troglodytes];XP_003308601.1//PREDICTED: thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 1 isoform X2 [Pan troglodytes]","1//3"]
[51052,264,0.01,0.36,5.16992500144231,0.649465306175656,"*",0.499032,"PRLH","GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0005184//neuropeptide hormone activity;GO:0031861//prolactin-releasing peptide receptor binding;GO:0005179//hormone activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0048483//autonomic nervous system development;GO:0042755//eating behavior;GO:0032868//response to insulin;GO:0040014//regulation of multicellular organism growth;GO:0002021//response to dietary excess;GO:0001894//tissue homeostasis;GO:0006112//energy reserve metabolic process;GO:0045444//fat cell differentiation;GO:0009749//response to glucose;GO:0002023//reduction of food intake in response to dietary excess;GO:0006629//lipid metabolic process","K05269//Prolactin-releasing peptide","XP_003813153.2//PREDICTED: prolactin-releasing peptide [Pan paniscus]","1//3"]
[90019,1569,0.01,0.36,5.16992500144231,0.0205839965625,"*",7.75218E-3,"SYT8","GO:0030672//synaptic vesicle membrane;GO:0016021//integral component of membrane;GO:0001669//acrosomal vesicle;GO:0005886//plasma membrane","GO:0005544//calcium-dependent phospholipid binding;GO:0030276//clathrin binding;GO:0005509//calcium ion binding;GO:0019905//syntaxin binding;GO:0048306//calcium-dependent protein binding","GO:0006906//vesicle fusion;GO:0048488//synaptic vesicle endocytosis;GO:0007340//acrosome reaction;GO:0048791//calcium ion-regulated exocytosis of neurotransmitter;GO:0017158//regulation of calcium ion-dependent exocytosis","K19908//synaptotagmin-8","NP_612634.3//synaptotagmin-8 isoform 2 [Homo sapiens];NP_001277261.1//synaptotagmin-8 isoform 1 [Homo sapiens];NP_001277263.1//synaptotagmin-8 isoform 4 [Homo sapiens];NP_001277262.1//synaptotagmin-8 isoform 3 [Homo sapiens]","1//3;4"]
[4070,2080,0.01,0.35,5.12928301694497,0.00591130904074995,"*",1.934294E-3,"TACSTD2","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0009925//basal plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005829//cytosol;GO:0016328//lateral plasma membrane","GO:0004872//receptor activity","GO:0090191//negative regulation of branching involved in ureteric bud morphogenesis;GO:1900025//negative regulation of substrate adhesion-dependent cell spreading;GO:0007601//visual perception;GO:0007166//cell surface receptor signaling pathway;GO:0050678//regulation of epithelial cell proliferation;GO:0010633//negative regulation of epithelial cell migration;GO:0098609//cell-cell adhesion;GO:0060675//ureteric bud morphogenesis;GO:0051497//negative regulation of stress fiber assembly;GO:0008283//cell proliferation;GO:2000146//negative regulation of cell motility;GO:2000738//positive regulation of stem cell differentiation;GO:1900028//negative regulation of ruffle assembly","K17288//tumor-associated calcium signal transducer 2","XP_003265191.1//PREDICTED: tumor-associated calcium signal transducer 2 [Nomascus leucogenys]","2//1"]
[4493,519,0.01,0.34,5.08746284125034,0.392847560773481,"*",0.249274,"MT1E","NA","NA","NA","K14739//metallothionein 1/2","XP_009194736.1//metallothionein-1E isoform X2 [Papio anubis]","3//A2MP1"]
[165904,3067,0.01,0.34,5.08746284125034,4.60541472157051E-4,"Up",1.204258E-4,"XIRP1","GO:0001725//stress fiber;GO:0005925//focal adhesion;GO:0030054//cell junction;GO:0031941//filamentous actin","GO:0003779//actin binding;GO:0003723//RNA binding","GO:0030036//actin cytoskeleton organization;GO:0032091//negative regulation of protein binding;GO:0007507//heart development","K16628//collagen, type VII, alpha;K17582//antigen KI-67","NP_001185550.1//xin actin-binding repeat-containing protein 1 isoform 2 [Homo sapiens];NP_919269.2//xin actin-binding repeat-containing protein 1 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[101928917,1184,0.01,0.33,5.04439411935845,0.127722181771436,"*",0.062198,"HSFX3","GO:0005634//nucleus","GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0006351//transcription, DNA-templated","K09415//heat shock transcription factor 2;K07612//gap junction alpha-3 protein;K09414//heat shock transcription factor 1;K15694//RING finger protein 43 [EC:2.3.2.27];K16482//centriolar protein POC1","NP_001310008.1//heat shock transcription factor, X-linked member 3 [Homo sapiens]","1//3"]
[727832,4013,0.01,0.33,5.04439411935845,{"v":6.69914478792959e-05,"d":"6.70E-05"},"Up",{"v":1.500954E-5,"d":"1.50E-05"},"GOLGA6L6","NA","NA","NA","K18626//trichohyalin;K20358//golgin subfamily A member 2","NP_001138476.2//golgin subfamily A member 6-like protein 6 [Homo sapiens]","2//1"]
[6441,1299,0.01,0.31,4.95419631038688,0.0702069615504315,"*",0.0310688,"SFTPD","GO:0005581//collagen trimer","GO:0005201//extracellular matrix structural constituent","NA","K06236//collagen, type I, alpha","XP_020559369.1//collagen alpha-1(I) chain-like [Oryzias latipes]",4]
[3266,826,0.01,0.3,4.90689059560852,0.226283068077361,"*",0.1245166,"ERAS","GO:0016020//membrane;GO:0005886//plasma membrane","GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0007165//signal transduction","K17196//GTPase Eras","NP_853510.1//GTPase ERas precursor [Homo sapiens]","3//A2MP1"]
[57817,598,0.01,0.29,4.85798099512757,0.392112543180699,"*",0.249274,"HAMP","GO:0045179//apical cortex;GO:0005615//extracellular space;GO:0005623//cell;GO:0005576//extracellular region;GO:0014704//intercalated disc","GO:0097690//iron channel inhibitor activity;GO:0005102//receptor binding;GO:0005179//hormone activity","GO:0071481//cellular response to X-ray;GO:0006879//cellular iron ion homeostasis;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:1904255//negative regulation of iron channel activity;GO:0097421//liver regeneration;GO:0071222//cellular response to lipopolysaccharide;GO:0002092//positive regulation of receptor internalization;GO:0071356//cellular response to tumor necrosis factor;GO:0045471//response to ethanol;GO:1902916//positive regulation of protein polyubiquitination;GO:0071354//cellular response to interleukin-6;GO:0033189//response to vitamin A;GO:0010043//response to zinc ion;GO:0010039//response to iron ion;GO:0031640//killing of cells of other organism;GO:0032413//negative regulation of ion transmembrane transporter activity;GO:0061051//positive regulation of cell growth involved in cardiac muscle cell development;GO:0050829//defense response to Gram-negative bacterium;GO:0042742//defense response to bacterium;GO:2000646//positive regulation of receptor catabolic process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0050830//defense response to Gram-positive bacterium;GO:1904039//negative regulation of ferrous iron export;GO:0036017//response to erythropoietin;GO:0050832//defense response to fungus;GO:0060586//multicellular organismal iron ion homeostasis;GO:0006953//acute-phase response;GO:1904479//negative regulation of intestinal absorption;GO:0007568//aging;GO:1903413//cellular response to bile acid;GO:0034760//negative regulation of iron ion transmembrane transport;GO:1990641//response to iron ion starvation;GO:0006955//immune response","NA","NP_066998.1//hepcidin preproprotein [Homo sapiens]","3//A2MP1"]
[100996741,3409,0.01,0.28,4.8073549220576,0.000872278089241223,"Up",2.41086E-4,"LOC100996741","NA","NA","NA","NA","XP_011817615.1//PREDICTED: protein FAM231A/C-like [Colobus angolensis palliatus]","1//3"]
[2352,948,0.01,0.28,4.8073549220576,0.226721551168357,"*",0.1245166,"FOLR3","GO:1904724//tertiary granule lumen;GO:0016020//membrane;GO:0035580//specific granule lumen;GO:0019898//extrinsic component of membrane;GO:0005576//extracellular region","GO:0005542//folic acid binding","GO:0015884//folic acid transport;GO:0043312//neutrophil degranulation","K13649//folate receptor","XP_008018204.1//PREDICTED: folate receptor gamma isoform X1 [Chlorocebus sabaeus];P41439.1//RecName: Full=Folate receptor gamma; Short=FR-gamma; AltName: Full=Folate receptor 3; Flags: Precursor","1//3;3//A2MP1"]
[200931,1455,0.01,0.28,4.8073549220576,0.0702268305079949,"*",0.0310688,"SLC51A","GO:0043234//protein complex;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane","GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0005215//transporter activity","GO:0006810//transport;GO:0015721//bile acid and bile salt transport","K14360//organic solute transporter subunit alpha","NP_689885.4//organic solute transporter subunit alpha [Homo sapiens]",5]
[3659,3557,11.45,291.45,4.66982889820956,0,"Up",0,"IRF1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0000790//nuclear chromatin;GO:0005737//cytoplasm","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:0043565//sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0060337//type I interferon signaling pathway;GO:0034124//regulation of MyD88-dependent toll-like receptor signaling pathway;GO:0032481//positive regulation of type I interferon production;GO:0071260//cellular response to mechanical stimulus;GO:0007596//blood coagulation;GO:2000564//regulation of CD8-positive, alpha-beta T cell proliferation;GO:0007050//cell cycle arrest;GO:0045893//positive regulation of transcription, DNA-templated;GO:0043374//CD8-positive, alpha-beta T cell differentiation;GO:0035458//cellular response to interferon-beta;GO:0050776//regulation of immune response;GO:0008285//negative regulation of cell proliferation;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045084//positive regulation of interleukin-12 biosynthetic process;GO:0032728//positive regulation of interferon-beta production;GO:0051607//defense response to virus;GO:0006351//transcription, DNA-templated;GO:0045088//regulation of innate immune response;GO:0006366//transcription from RNA polymerase II promoter;GO:0002819//regulation of adaptive immune response;GO:0006915//apoptotic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0051726//regulation of cell cycle;GO:0045590//negative regulation of regulatory T cell differentiation","K09444//interferon regulatory factor 1","NP_001341853.1//interferon regulatory factor 1 isoform 2 [Homo sapiens];XP_003464582.2//PREDICTED: interferon regulatory factor 1 isoform X2 [Cavia porcellus];NP_001341854.1//interferon regulatory factor 1 isoform 3 [Homo sapiens]","1//3;2//1"]
[8651,1216,0.87,21.4,4.62045158543978,{"v":8.59047047751938e-76,"d":"8.59E-76"},"Up",{"v":6.93734e-78,"d":"6.94E-78"},"SOCS1","GO:0005654//nucleoplasm;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0005737//cytoplasm","GO:0004860//protein kinase inhibitor activity;GO:0005159//insulin-like growth factor receptor binding;GO:0019901//protein kinase binding","GO:0045591//positive regulation of regulatory T cell differentiation;GO:0007259//JAK-STAT cascade;GO:0016567//protein ubiquitination;GO:0046426//negative regulation of JAK-STAT cascade;GO:0042532//negative regulation of tyrosine phosphorylation of STAT protein;GO:0071230//cellular response to amino acid stimulus;GO:0050707//regulation of cytokine secretion;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0006469//negative regulation of protein kinase activity;GO:0010533//regulation of activation of Janus kinase activity;GO:0060334//regulation of interferon-gamma-mediated signaling pathway;GO:0045444//fat cell differentiation;GO:0019221//cytokine-mediated signaling pathway","K04694//suppressor of cytokine signaling 1","XP_019569617.1//PREDICTED: suppressor of cytokine signaling 1 [Rhinolophus sinicus]","1//3"]
[256710,1016,0.01,0.24,4.58496250072116,0.227083932914716,"*",0.1245166,"GLIPR1L1","GO:0045121//membrane raft;GO:0005576//extracellular region;GO:0001669//acrosomal vesicle;GO:0005886//plasma membrane;GO:0031225//anchored component of membrane","NA","GO:0007338//single fertilization","K20412//peptidase inhibitor 16;K19919//cysteine-rich secretory protein","XP_011536436.2//PREDICTED: GLIPR1-like protein 1 isoform X1 [Homo sapiens];NP_001291893.1//GLIPR1-like protein 1 isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[441161,689,0.01,0.24,4.58496250072116,0.395030047222222,"*",0.249274,"OOEP","GO:0005938//cell cortex;GO:0043234//protein complex;GO:0045177//apical part of cell","GO:0003723//RNA binding","GO:0009566//fertilization;GO:0009880//embryonic pattern specification;GO:0006468//protein phosphorylation;GO:0001701//in utero embryonic development;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0007566//embryo implantation;GO:0043623//cellular protein complex assembly","NA","NP_001073976.1//oocyte-expressed protein homolog [Homo sapiens]","2//1"]
[259283,1058,0.01,0.24,4.58496250072116,0.226954377955272,"*",0.1245166,"MDS2","GO:0005615//extracellular space","NA","NA","K09228//KRAB domain-containing zinc finger protein","NP_001335004.1//myelodysplastic syndrome 2 translocation-associated protein [Homo sapiens]","1//3"]
[143678,369,0.01,0.24,4.58496250072116,0.642606785006046,"*",0.499032,"C11orf94","GO:0005576//extracellular region","NA","NA","NA","NP_001073915.2//uncharacterized protein C11orf94 precursor [Homo sapiens]","2//1"]
[51513,1582,0.11,2.54,4.52925306813487,{"v":1.22866683333333e-11,"d":"1.23E-11"},"Up",{"v":1.12606e-12,"d":"1.13E-12"},"ETV7","GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0001227//transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0009887//animal organ morphogenesis;GO:0030154//cell differentiation;GO:0006366//transcription from RNA polymerase II promoter","K03211//ETS translocation variant 6/7","NP_001193968.1//transcription factor ETV7 isoform 6 [Homo sapiens];NP_001193964.1//transcription factor ETV7 isoform 2 [Homo sapiens];NP_001193965.1//transcription factor ETV7 isoform 3 [Homo sapiens];NP_001193966.1//transcription factor ETV7 isoform 4 [Homo sapiens];NP_057219.1//transcription factor ETV7 isoform 1 [Homo sapiens];NP_001193967.1//transcription factor ETV7 isoform 5 [Homo sapiens]","1//3;3//A2MP1"]
[10912,1087,0.01,0.23,4.52356195605701,0.226514994693087,"*",0.1245166,"GADD45G","GO:0005634//nucleus;GO:0005737//cytoplasm","NA","GO:0046330//positive regulation of JNK cascade;GO:1900745//positive regulation of p38MAPK cascade;GO:0043065//positive regulation of apoptotic process;GO:0000185//activation of MAPKKK activity;GO:0030154//cell differentiation;GO:0007275//multicellular organism development;GO:0006950//response to stress;GO:0051726//regulation of cell cycle;GO:0006915//apoptotic process","K04402//growth arrest and DNA-damage-inducible protein","XP_005408930.1//PREDICTED: growth arrest and DNA damage-inducible protein GADD45 gamma [Chinchilla lanigera]","3//A2MP1"]
[3814,731,0.01,0.23,4.52356195605701,0.392073934226073,"*",0.249274,"KISS1","NA","NA","GO:0007186//G-protein coupled receptor signaling pathway;GO:0046697//decidualization","NA","XP_003273200.2//PREDICTED: uncharacterized protein LOC100593139 [Nomascus leucogenys]","3//A2MP1"]
[107080644,1212,0.01,0.22,4.4594316186373,0.226902597353411,"*",0.1245166,"CNPY3-GNMT","GO:0005829//cytosol","GO:0005542//folic acid binding;GO:0017174//glycine N-methyltransferase activity;GO:0016594//glycine binding","GO:0051289//protein homotetramerization;GO:0046500//S-adenosylmethionine metabolic process;GO:0006111//regulation of gluconeogenesis;GO:0006730//one-carbon metabolic process;GO:0005977//glycogen metabolic process;GO:0006555//methionine metabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0006464//cellular protein modification process","K00552//glycine N-methyltransferase [EC:2.1.1.20]","NP_001305785.1//uncharacterized protein LOC107080644 isoform 2 [Homo sapiens];NP_001305786.1//uncharacterized protein LOC107080644 isoform 1 precursor [Homo sapiens];NP_001305787.1//uncharacterized protein LOC107080644 isoform 3 precursor [Homo sapiens]","1//3"]
[642778,1098,0.01,0.22,4.4594316186373,0.394169756087903,"*",0.249274,"NPIPA3","NA","NA","NA","NA","XP_011521050.1//PREDICTED: nuclear pore complex-interacting protein family member A1 isoform X1 [Homo sapiens]","1//3"]
[5047,764,0.01,0.22,4.4594316186373,0.393935781163435,"*",0.249274,"PAEP","GO:0005576//extracellular region","GO:0036094//small molecule binding","GO:0006810//transport;GO:1902491//negative regulation of sperm capacitation;GO:2000667//positive regulation of interleukin-13 secretion;GO:2000359//regulation of binding of sperm to zona pellucida;GO:0006915//apoptotic process;GO:0032725//positive regulation of granulocyte macrophage colony-stimulating factor production;GO:0007275//multicellular organism development;GO:2000778//positive regulation of interleukin-6 secretion","NA","CAB43305.1//hypothetical protein, partial [Homo sapiens]","1//3;3//A2MP1;2//1"]
[9651,5159,0.01,0.22,4.4594316186373,1.27622958468492E-4,"Up",{"v":3.00482e-05,"d":"3.00E-05"},"PLCH2","GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0004435//phosphatidylinositol phospholipase C activity;GO:0005509//calcium ion binding;GO:0004871//signal transducer activity","GO:0016042//lipid catabolic process;GO:0046488//phosphatidylinositol metabolic process;GO:0043647//inositol phosphate metabolic process;GO:0035556//intracellular signal transduction","K19006//phosphatidylinositol phospholipase C, eta [EC:3.1.4.11]","NP_001289941.1//1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 isoform 2 [Homo sapiens];NP_055453.2//1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 isoform 1 [Homo sapiens];XP_016858361.1//PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 isoform X3 [Homo sapiens]","1//3;3//A2MP1"]
[6317,1793,0.01,0.22,4.4594316186373,0.0702666021803766,"*",0.0310688,"SERPINB3","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0031410//cytoplasmic vesicle;GO:0031982//vesicle;GO:0005737//cytoplasm;GO:0035578//azurophil granule lumen;GO:0005576//extracellular region","GO:0002020//protease binding;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0001618//virus receptor activity;GO:0004869//cysteine-type endopeptidase inhibitor activity","GO:0010466//negative regulation of peptidase activity;GO:0030335//positive regulation of cell migration;GO:0045861//negative regulation of proteolysis;GO:0010951//negative regulation of endopeptidase activity;GO:0010950//positive regulation of endopeptidase activity;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0043508//negative regulation of JUN kinase activity;GO:0035425//autocrine signaling;GO:0038001//paracrine signaling;GO:0043086//negative regulation of catalytic activity;GO:0043312//neutrophil degranulation;GO:0008284//positive regulation of cell proliferation","K13963//serpin B","NP_008850.1//serpin B3 [Homo sapiens]","2//1"]
[84366,403,0.01,0.22,4.4594316186373,0.640644311500442,"*",0.499032,"PRAC1","GO:0005634//nucleus","NA","NA","NA","NP_115767.1//small nuclear protein PRAC1 [Homo sapiens]","2//1"]
[2619,2844,0.01,0.22,4.4594316186373,0.0110695703579098,"*",0.00387234,"GAS1","GO:0016021//integral component of membrane;GO:0046658//anchored component of plasma membrane;GO:0005886//plasma membrane","NA","GO:0045165//cell fate commitment;GO:0008589//regulation of smoothened signaling pathway;GO:0045930//negative regulation of mitotic cell cycle;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0007050//cell cycle arrest;GO:0060628//regulation of ER to Golgi vesicle-mediated transport;GO:0010955//negative regulation of protein processing;GO:0048589//developmental growth;GO:0042981//regulation of apoptotic process","K06232//growth arrest-specific 1","XP_019479621.1//PREDICTED: growth arrest-specific protein 1 [Hipposideros armiger]","2//1"]
[219537,1649,0.05,1.08,4.43295940727611,{"v":1.46860112953041E-5,"d":"1.47E-05"},"Up",{"v":2.91716E-6,"d":"2.92E-06"},"SMTNL1","GO:0005634//nucleus;GO:0031430//M band;GO:0031674//I band","GO:0005523//tropomyosin binding;GO:0043621//protein self-association;GO:0097718//disordered domain specific binding;GO:0005516//calmodulin binding;GO:0008157//protein phosphatase 1 binding;GO:0051401//CH domain binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0048644//muscle organ morphogenesis;GO:0042493//response to drug;GO:0045907//positive regulation of vasoconstriction;GO:0018105//peptidyl-serine phosphorylation;GO:0014823//response to activity;GO:0097756//negative regulation of blood vessel diameter","K19538//retinitis pigmentosa 1","NP_001099035.2//smoothelin-like protein 1 [Homo sapiens]","2//1"]
[347549,1898,0.01,0.21,4.39231742277876,0.0702467107147912,"*",0.0310688,"CENPVL3","NA","NA","NA","K06237//collagen, type IV, alpha;K17498//transcription factor SPN1;K16630//collagen, type XXII, alpha;K19720//collagen, type III, alpha","NP_001342205.1//centromere protein V like 3 [Homo sapiens]","1//3"]
[100529257,1856,0.01,0.21,4.39231742277876,0.127541829525032,"*",0.062198,"SYNJ2BP-COX16","GO:0031307//integral component of mitochondrial outer membrane","GO:0008022//protein C-terminus binding","GO:0048312//intracellular distribution of mitochondria","K20057//synaptojanin-2-binding protein","NP_001189477.1//SYNJ2BP-COX16 protein isoform 2 [Homo sapiens];NP_001189476.1//SYNJ2BP-COX16 protein isoform 1 [Homo sapiens];NP_001189478.1//SYNJ2BP-COX16 protein isoform 3 [Homo sapiens]","2//1"]
[135644,2092,0.01,0.21,4.39231742277876,0.0701970312871287,"*",0.0310688,"TRIM40","GO:0005622//intracellular;GO:0008385//IkappaB kinase complex","GO:0008270//zinc ion binding","GO:0030308//negative regulation of cell growth;GO:0045116//protein neddylation;GO:1901223//negative regulation of NIK/NF-kappaB signaling;GO:1900181//negative regulation of protein localization to nucleus;GO:0042177//negative regulation of protein catabolic process;GO:0032088//negative regulation of NF-kappaB transcription factor activity","K12016//tripartite motif-containing protein 40","NP_001273562.1//tripartite motif-containing protein 40 isoform a [Homo sapiens];NP_619645.1//tripartite motif-containing protein 40 isoform b [Homo sapiens]","1//3;4"]
[27290,420,0.01,0.21,4.39231742277876,0.640592829315333,"*",0.499032,"SPINK4","GO:0005576//extracellular region","GO:0004867//serine-type endopeptidase inhibitor activity","GO:0042493//response to drug","NA","NP_055286.1//serine protease inhibitor Kazal-type 4 precursor [Homo sapiens]","2//1"]
[11009,1621,0.01,0.2,4.32192809488736,0.127656540151612,"*",0.062198,"IL24","GO:0005615//extracellular space;GO:0005576//extracellular region","GO:0005125//cytokine activity","GO:0042060//wound healing;GO:0071222//cellular response to lipopolysaccharide;GO:0030336//negative regulation of cell migration;GO:0006915//apoptotic process;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0042501//serine phosphorylation of STAT protein;GO:0071353//cellular response to interleukin-4;GO:0008285//negative regulation of cell proliferation;GO:0008284//positive regulation of cell proliferation","K05444//interleukin 19/20/24","NP_006841.1//interleukin-24 isoform 1 precursor [Homo sapiens];NP_001172086.1//interleukin-24 isoform 4 precursor [Homo sapiens];NP_001172085.1//interleukin-24 isoform 3 precursor [Homo sapiens]","1//3;3//A2MP1"]
[54145,460,0.01,0.2,4.32192809488736,0.647355625142115,"*",0.499032,"H2BFS","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0000786//nucleosome","GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity","GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0021762//substantia nigra development;GO:0006334//nucleosome assembly;GO:0050830//defense response to Gram-positive bacterium;GO:0002227//innate immune response in mucosa;GO:0019731//antibacterial humoral response","K11252//histone H2B","NP_059141.1//histone H2B type F-S [Homo sapiens]","2//1"]
[645073,441,0.01,0.2,4.32192809488736,0.642658591422122,"*",0.499032,"GAGE12G","NA","NA","NA","NA","NP_001468.1//G antigen 12I [Homo sapiens];NP_001341351.1//G antigen 12G isoform 2 [Homo sapiens]","1//3;2//1"]
[51554,2356,0.01,0.2,4.32192809488736,0.0379875721115538,"*",0.0155194,"ACKR4","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0055037//recycling endosome;GO:0005886//plasma membrane;GO:0005769//early endosome","GO:0005044//scavenger receptor activity;GO:0019956//chemokine binding;GO:0004950//chemokine receptor activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0006955//immune response;GO:0006935//chemotaxis","K04186//C-C chemokine receptor-like 1","NP_057641.1//atypical chemokine receptor 4 [Homo sapiens]","3//A2MP1;2//1"]
[3018,431,0.01,0.2,4.32192809488736,0.639770238202247,"*",0.499032,"HIST1H2BB","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000784//nuclear chromosome, telomeric region;GO:0005829//cytosol;GO:0000786//nucleosome","GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity","GO:0016567//protein ubiquitination;GO:0006334//nucleosome assembly","K11252//histone H2B","XP_003502246.1//PREDICTED: histone H2B type 1 isoform X1 [Cricetulus griseus]","2//1"]
[11202,1038,0.01,0.19,4.24792751344359,0.651961819579619,"*",0.499032,"KLK8","GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0004252//serine-type endopeptidase activity","GO:0009611//response to wounding;GO:0048681//negative regulation of axon regeneration;GO:0043616//keratinocyte proliferation;GO:0008219//cell death;GO:0070268//cornification;GO:0007613//memory;GO:0048812//neuron projection morphogenesis;GO:0050808//synapse organization;GO:0031642//negative regulation of myelination;GO:0050807//regulation of synapse organization","K08650//kallikrein 8 [EC:3.4.21.118]","XP_021561667.1//kallikrein-8 isoform X2 [Carlito syrichta];SFW93206.1//TPA: kallikrein H [Homo sapiens];NP_653088.1//kallikrein-8 isoform 2 precursor [Homo sapiens];XP_012365451.1//PREDICTED: kallikrein-8 isoform X3 [Nomascus leucogenys];NP_009127.1//kallikrein-8 isoform 1 preproprotein [Homo sapiens]","1//3;3//A2MP1;2//1"]
[727684,453,0.01,0.19,4.24792751344359,0.6496240867085,"*",0.499032,"C1orf195","NA","NA","NA","NA","NP_001265431.1//putative uncharacterized protein C1orf195 isoform 2 [Homo sapiens];NP_001265430.1//putative uncharacterized protein C1orf195 isoform 1 [Homo sapiens]","1//3"]
[286380,2218,0.01,0.19,4.24792751344359,0.0702566550396376,"*",0.0310688,"FOXD4L3","GO:0005634//nucleus","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0008301//DNA binding, bending","GO:0009653//anatomical structure morphogenesis;GO:0030154//cell differentiation;GO:0006351//transcription, DNA-templated","K09397//forkhead box protein D","AAI03888.1//Forkhead box D4-like 6 [Homo sapiens]",4]
[7356,452,0.01,0.19,4.24792751344359,0.641779016826342,"*",0.499032,"SCGB1A1","GO:0070062//extracellular exosome;GO:0030141//secretory granule;GO:0005615//extracellular space;GO:0005791//rough endoplasmic reticulum;GO:0005635//nuclear envelope;GO:0005737//cytoplasm","GO:0019834//phospholipase A2 inhibitor activity;GO:0097160//polychlorinated biphenyl binding","GO:0032696//negative regulation of interleukin-13 production;GO:0034021//response to silicon dioxide;GO:0034097//response to cytokine;GO:0032496//response to lipopolysaccharide;GO:0010193//response to ozone;GO:0007566//embryo implantation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0042130//negative regulation of T cell proliferation;GO:0043488//regulation of mRNA stability;GO:0051384//response to glucocorticoid;GO:0007565//female pregnancy;GO:0042493//response to drug;GO:0007165//signal transduction;GO:0032713//negative regulation of interleukin-4 production;GO:0009410//response to xenobiotic stimulus;GO:0032714//negative regulation of interleukin-5 production;GO:0050727//regulation of inflammatory response;GO:0071774//response to fibroblast growth factor;GO:0032689//negative regulation of interferon-gamma production","NA","NP_003348.1//uteroglobin precursor [Homo sapiens]",4]
[100526772,1459,0.03,0.54,4.16992500144231,5.91017833894415E-3,"*",1.934294E-3,"TMEM110-MUSTN1","GO:0005634//nucleus;GO:0016021//integral component of membrane","NA","GO:0035988//chondrocyte proliferation;GO:0002062//chondrocyte differentiation;GO:0042246//tissue regeneration","K20179//vacuolar protein sorting-associated protein 11","NP_001185903.2//TMEM110-MUSTN1 fusion protein [Homo sapiens]","2//1"]
[5539,480,0.01,0.18,4.16992500144231,0.654155355982275,"*",0.499032,"PPY","GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0001664//G-protein coupled receptor binding;GO:0005102//receptor binding;GO:0005184//neuropeptide hormone activity;GO:0005179//hormone activity","GO:0009306//protein secretion;GO:0032098//regulation of appetite;GO:0007631//feeding behavior;GO:0007586//digestion;GO:0007267//cell-cell signaling;GO:0007218//neuropeptide signaling pathway","K05234//pancreatic polypeptide","NP_001306138.1//pancreatic prohormone isoform 2 precursor [Homo sapiens];XP_011523280.1//PREDICTED: pancreatic prohormone isoform X1 [Homo sapiens]","1//3;4"]
[1672,484,0.01,0.18,4.16992500144231,0.654101679494543,"*",0.499032,"DEFB1","GO:1990742//microvesicle;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0019898//extrinsic component of membrane;GO:0005576//extracellular region;GO:0097225//sperm midpiece;GO:0005622//intracellular;GO:0005796//Golgi lumen","GO:0042802//identical protein binding;GO:0031731//CCR6 chemokine receptor binding","GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0050829//defense response to Gram-negative bacterium;GO:0042742//defense response to bacterium;GO:0035584//calcium-mediated signaling using intracellular calcium source;GO:0019730//antimicrobial humoral response;GO:0060474//positive regulation of flagellated sperm motility involved in capacitation;GO:0033574//response to testosterone;GO:0006935//chemotaxis;GO:0050830//defense response to Gram-positive bacterium;GO:0045087//innate immune response;GO:0007186//G-protein coupled receptor signaling pathway;GO:0002526//acute inflammatory response;GO:0019933//cAMP-mediated signaling;GO:0006955//immune response;GO:0002227//innate immune response in mucosa;GO:0019731//antibacterial humoral response;GO:0009617//response to bacterium","NA","NP_005209.1//beta-defensin 1 preproprotein [Homo sapiens]","3//A2MP1"]
[8354,477,0.01,0.18,4.16992500144231,0.653029996559351,"*",0.499032,"HIST1H3I","NA","NA","NA","K11253//histone H3","XP_016810252.1//PREDICTED: uncharacterized protein LOC100608783 [Pan troglodytes]","2//1"]
[255426,2216,0.01,0.18,4.16992500144231,0.070296460509915,"*",0.0310688,"RASGEF1C","GO:0005622//intracellular","GO:0005085//guanyl-nucleotide exchange factor activity","GO:0007264//small GTPase mediated signal transduction","K03781//catalase [EC:1.11.1.6];K08018//Rap guanine nucleotide exchange factor 2;K03099//son of sevenless","AAH36802.1//RASGEF1C protein, partial [Homo sapiens]","3//A2MP1"]
[1417,896,0.01,0.18,4.16992500144231,0.393663161245675,"*",0.249274,"CRYBB3","NA","GO:0005212//structural constituent of eye lens","GO:0007601//visual perception","K13596//activin receptor type-2B [EC:2.7.11.30];K16810//TBCC domain-containing protein 1;K01886//glutaminyl-tRNA synthetase [EC:6.1.1.18]","XP_011528204.1//PREDICTED: beta-crystallin B3 isoform X1 [Homo sapiens]",4]
[131540,1370,0.01,0.18,4.16992500144231,0.226386087912588,"*",0.1245166,"ZDHHC19","GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane","GO:0019706//protein-cysteine S-palmitoyltransferase activity","NA","K18932//palmitoyltransferase [EC:2.3.1.225]","NP_001034706.1//probable palmitoyltransferase ZDHHC19 [Homo sapiens]","1//3"]
[85235,481,0.01,0.18,4.16992500144231,0.642969605420229,"*",0.499032,"HIST1H2AH","GO:0005634//nucleus;GO:0000786//nucleosome","GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity","GO:0006334//nucleosome assembly;GO:0006352//DNA-templated transcription, initiation","K11251//histone H2A;K11254//histone H4;K11253//histone H3","XP_019687249.1//PREDICTED: histone H2A type 1-E isoform X2 [Felis catus]","2//1"]
[6355,1351,0.01,0.18,4.16992500144231,0.226154425059693,"*",0.1245166,"CCL8","GO:0005615//extracellular space;GO:0005623//cell","GO:0004672//protein kinase activity;GO:0016004//phospholipase activator activity;GO:0008009//chemokine activity","GO:0006955//immune response;GO:0007267//cell-cell signaling;GO:0006816//calcium ion transport;GO:0006874//cellular calcium ion homeostasis;GO:0006887//exocytosis","K16596//C-C motif chemokine 8","XP_008009204.1//PREDICTED: C-C motif chemokine 8 [Chlorocebus sabaeus]","2//1"]
[3512,1413,0.01,0.17,4.08746284125034,0.226928484700513,"*",0.1245166,"JCHAIN","GO:0071756//pentameric IgM immunoglobulin complex;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0071750//dimeric IgA immunoglobulin complex;GO:0072562//blood microparticle;GO:0071751//secretory IgA immunoglobulin complex;GO:0005576//extracellular region;GO:0071748//monomeric IgA immunoglobulin complex;GO:0071752//secretory dimeric IgA immunoglobulin complex","GO:0034987//immunoglobulin receptor binding;GO:0030674//protein binding, bridging;GO:0019862//IgA binding;GO:0042803//protein homodimerization activity;GO:0003823//antigen binding","GO:0060267//positive regulation of respiratory burst;GO:0003094//glomerular filtration;GO:0050900//leukocyte migration;GO:0001895//retina homeostasis;GO:0002250//adaptive immune response;GO:0032461//positive regulation of protein oligomerization;GO:0006898//receptor-mediated endocytosis;GO:0006955//immune response;GO:0019731//antibacterial humoral response;GO:0045087//innate immune response","NA","XP_007997010.1//PREDICTED: immunoglobulin J chain isoform X1 [Chlorocebus sabaeus]","3//A2MP1"]
[56673,1942,0.01,0.17,4.08746284125034,0.12764014028777,"*",0.062198,"C11orf16","NA","NA","NA","NA","NP_065694.2//uncharacterized protein C11orf16 [Homo sapiens]","2//1"]
[10361,1118,0.01,0.17,4.08746284125034,0.391996739121874,"*",0.249274,"NPM2","NA","NA","NA","K11277//nucleophosmin 2;K11432//histone-lysine N-methyltransferase PRDM2 [EC:2.1.1.43]","XP_016814686.1//PREDICTED: nucleoplasmin-2 isoform X9 [Pan troglodytes];XP_003412535.1//PREDICTED: nucleoplasmin-2 [Loxodonta africana]","1//3"]
[100505724,510,0.01,0.17,4.08746284125034,0.639924313076985,"*",0.499032,"KRTAP9-7","GO:0005829//cytosol;GO:0045095//keratin filament","NA","GO:0031424//keratinization","K17582//antigen KI-67","NP_001264261.1//keratin-associated protein 9-7 [Homo sapiens]","1//3"]
[643246,809,0.01,0.17,4.08746284125034,0.639872946540376,"*",0.499032,"MAP1LC3B2","GO:0016020//membrane;GO:0005874//microtubule;GO:0031090//organelle membrane;GO:0031410//cytoplasmic vesicle;GO:0005622//intracellular;GO:0044754//autolysosome;GO:0012505//endomembrane system;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005776//autophagosome;GO:0005930//axoneme;GO:0000421//autophagosome membrane","GO:0031625//ubiquitin protein ligase binding","GO:0070257//positive regulation of mucus secretion;GO:0009267//cellular response to starvation;GO:0061024//membrane organization;GO:0000422//autophagy of mitochondrion;GO:0097352//autophagosome maturation;GO:0006995//cellular response to nitrogen starvation;GO:0006914//autophagy;GO:0000045//autophagosome assembly;GO:0016236//macroautophagy","K10435//microtubule-associated protein 1 light chain","XP_011536954.1//PREDICTED: microtubule-associated proteins 1A/1B light chain 3 beta 2 isoform X1 [Homo sapiens]","2//1"]
[149643,537,0.01,0.16,4,0.647776464163823,"*",0.499032,"SPATA45","NA","NA","NA","NA","EAW93375.1//hypothetical LOC149643, partial [Homo sapiens]","2//1"]
[84504,1019,0.01,0.16,4,0.392421688775007,"*",0.249274,"NKX6-2","GO:0005634//nucleus","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0010454//negative regulation of cell fate commitment;GO:0045687//positive regulation of glial cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0010455//positive regulation of cell fate commitment;GO:0031018//endocrine pancreas development;GO:0022010//central nervous system myelination;GO:0045686//negative regulation of glial cell differentiation;GO:0021913//regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification;GO:0050885//neuromuscular process controlling balance;GO:0021912//regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification","K09350//homeobox protein Nkx-6.2","NP_796374.1//homeobox protein Nkx-6.2 [Homo sapiens]","2//1"]
[2841,1484,0.01,0.16,4,0.226205864710565,"*",0.1245166,"GPR18","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0030659//cytoplasmic vesicle membrane","GO:0004930//G-protein coupled receptor activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway;GO:0032720//negative regulation of tumor necrosis factor production;GO:0002689//negative regulation of leukocyte chemotaxis;GO:0002300//CD8-positive, alpha-beta intraepithelial T cell differentiation;GO:0035025//positive regulation of Rho protein signal transduction;GO:0002305//CD8-positive, gamma-delta intraepithelial T cell differentiation;GO:0030217//T cell differentiation","K08410//G protein-coupled receptor 18","NP_005283.1//N-arachidonyl glycine receptor [Homo sapiens]","1//3;3//A2MP1"]
[3990,1614,0.01,0.15,3.90689059560852,0.227032093185709,"*",0.1245166,"LIPC","GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0034364//high-density lipoprotein particle;GO:0005576//extracellular region","GO:0004620//phospholipase activity;GO:0030169//low-density lipoprotein particle binding;GO:0004806//triglyceride lipase activity;GO:0008201//heparin binding;GO:0034185//apolipoprotein binding","GO:0019433//triglyceride catabolic process;GO:0008203//cholesterol metabolic process;GO:0034374//low-density lipoprotein particle remodeling;GO:0051004//regulation of lipoprotein lipase activity;GO:0034372//very-low-density lipoprotein particle remodeling;GO:0070328//triglyceride homeostasis;GO:0034375//high-density lipoprotein particle remodeling;GO:0034373//intermediate-density lipoprotein particle remodeling;GO:0034638//phosphatidylcholine catabolic process;GO:0042632//cholesterol homeostasis;GO:0043691//reverse cholesterol transport;GO:0034382//chylomicron remnant clearance;GO:0006633//fatty acid biosynthetic process;GO:0006629//lipid metabolic process","K22283//hepatic triacylglycerol lipase [EC:3.1.1.3]","NP_000227.2//hepatic triacylglycerol lipase precursor [Homo sapiens]","2//1"]
[10406,570,0.01,0.15,3.90689059560852,0.651642047576228,"*",0.499032,"WFDC2","GO:0070062//extracellular exosome;GO:0005615//extracellular space","GO:0004867//serine-type endopeptidase inhibitor activity;GO:0004866//endopeptidase inhibitor activity;GO:0019828//aspartic-type endopeptidase inhibitor activity;GO:0004869//cysteine-type endopeptidase inhibitor activity","GO:0006508//proteolysis;GO:0007283//spermatogenesis","K03910//alpha-2-macroglobulin","NP_006094.3//WAP four-disulfide core domain protein 2 precursor [Homo sapiens]","3//A2MP1"]
[11170,3190,0.01,0.15,3.90689059560852,0.0380166992179114,"*",0.0155194,"FAM107A","GO:0005634//nucleus;GO:0016607//nuclear speck;GO:0043005//neuron projection","NA","GO:0001558//regulation of cell growth","K08405//G protein-coupled receptor 25","XP_007192413.1//PREDICTED: protein FAM107A isoform X1 [Balaenoptera acutorostrata scammoni];BAG51416.1//unnamed protein product [Homo sapiens];XP_007982984.1//PREDICTED: protein FAM107A isoform X1 [Chlorocebus sabaeus];NP_001269643.1//protein FAM107A isoform c [Homo sapiens]","1//3;3//A2MP1;2//1"]
[84616,1099,0.01,0.15,3.90689059560852,0.393896812345435,"*",0.249274,"KRTAP4-4","NA","NA","NA","K00624//carnitine O-acetyltransferase [EC:2.3.1.7];K17582//antigen KI-67","XP_011901963.1//PREDICTED: keratin-associated protein 4-4 isoform X1 [Cercocebus atys]","1//3"]
[388381,566,0.01,0.15,3.90689059560852,0.649200844368434,"*",0.499032,"C17orf98","NA","NA","NA","NA","NP_001073934.1//uncharacterized protein C17orf98 [Homo sapiens]","2//1"]
[1842,3241,0.01,0.15,3.90689059560852,0.0379933939616858,"*",0.0155194,"ECM2","GO:0005615//extracellular space;GO:0005614//interstitial matrix;GO:0005578//proteinaceous extracellular matrix","GO:0070052//collagen V binding;GO:0005178//integrin binding;GO:0008201//heparin binding","GO:0007160//cell-matrix adhesion;GO:0030198//extracellular matrix organization;GO:0010811//positive regulation of cell-substrate adhesion","K08119//extracellular matrix protein 2","NP_001184224.1//extracellular matrix protein 2 isoform 2 precursor [Homo sapiens];NP_001384.1//extracellular matrix protein 2 isoform 1 precursor [Homo sapiens];CAD97940.1//hypothetical protein, partial [Homo sapiens]","1//3;3//A2MP1"]
[7932,1063,0.01,0.15,3.90689059560852,0.393624246342428,"*",0.249274,"OR2H2","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0007608//sensory perception of smell","K04257//olfactory receptor","XP_004043582.1//PREDICTED: olfactory receptor 2H2 [Gorilla gorilla gorilla]","3//A2MP1"]
[100132463,663,0.01,0.15,3.90689059560852,0.646882834374746,"*",0.499032,"CLDN24","GO:0016021//integral component of membrane;GO:0005923//bicellular tight junction;GO:0005886//plasma membrane","GO:0005198//structural molecule activity","NA","K06087//claudin","NP_001172078.1//putative claudin-24 [Homo sapiens]","1//3"]
[100505741,2155,0.01,0.15,3.90689059560852,0.127607353198048,"*",0.062198,"SPATA1","NA","NA","NA","K12478//early endosome antigen 1","NP_001297085.1//spermatogenesis-associated protein 1 [Homo sapiens]","1//3"]
[6359,1073,0.01,0.15,3.90689059560852,0.393196689641552,"*",0.249274,"CCL15","GO:0005615//extracellular space;GO:0005623//cell","GO:0008201//heparin binding;GO:0005102//receptor binding;GO:0008009//chemokine activity;GO:0048020//CCR chemokine receptor binding;GO:0042056//chemoattractant activity","GO:0048247//lymphocyte chemotaxis;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007165//signal transduction;GO:0030593//neutrophil chemotaxis;GO:0070098//chemokine-mediated signaling pathway;GO:0007267//cell-cell signaling;GO:0043547//positive regulation of GTPase activity;GO:0071356//cellular response to tumor necrosis factor;GO:0006954//inflammatory response;GO:0071346//cellular response to interferon-gamma;GO:0071347//cellular response to interleukin-1;GO:0006955//immune response;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0002548//monocyte chemotaxis;GO:0006935//chemotaxis;GO:0006874//cellular calcium ion homeostasis","K05511//C-C motif chemokine 15/23","NP_116741.2//C-C motif chemokine 15 preproprotein [Homo sapiens]",5]
[10871,1602,0.01,0.15,3.90689059560852,0.22641185752988,"*",0.1245166,"CD300C","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004888//transmembrane signaling receptor activity","GO:0002376//immune system process;GO:0006968//cellular defense response;GO:0050776//regulation of immune response","K06719//CD300 antigen","NP_006669.1//CMRF35-like molecule 6 precursor [Homo sapiens]",4]
[100507650,1629,0.01,0.15,3.90689059560852,0.226257327767034,"*",0.1245166,"RNF212B","GO:0000795//synaptonemal complex","GO:0046872//metal ion binding;GO:0019789//SUMO transferase activity","GO:0007129//synapsis;GO:0016925//protein sumoylation","K09379//zinc finger homeobox protein 2;K10330//ankyrin repeat and SOCS box protein 8","NP_001269251.1//RING finger protein 212B [Homo sapiens]","2//1"]
[644591,738,0.01,0.15,3.90689059560852,0.64395647208983,"*",0.499032,"PPIAL4G","GO:0005737//cytoplasm","GO:0003755//peptidyl-prolyl cis-trans isomerase activity","GO:0006457//protein folding","K12738//peptidylprolyl cis-trans isomerase A-like 4 [EC:5.2.1.8]","NP_001116540.1//peptidyl-prolyl cis-trans isomerase A-like 4G [Homo sapiens]","1//3"]
[434,584,0.01,0.15,3.90689059560852,0.6406958019611,"*",0.499032,"ASIP","GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005622//intracellular","GO:0031782//type 4 melanocortin receptor binding;GO:0005102//receptor binding;GO:0031781//type 3 melanocortin receptor binding","GO:0071514//genetic imprinting;GO:0007165//signal transduction;GO:0048023//positive regulation of melanin biosynthetic process;GO:0006091//generation of precursor metabolites and energy;GO:0007267//cell-cell signaling;GO:0042438//melanin biosynthetic process;GO:0032402//melanosome transport;GO:0008343//adult feeding behavior;GO:0009755//hormone-mediated signaling pathway;GO:0040030//regulation of molecular function, epigenetic;GO:0032438//melanosome organization","K08725//agouti signaling protein","XP_005260469.1//PREDICTED: agouti-signaling protein isoform X1 [Homo sapiens]","2//1"]
[26581,594,0.01,0.14,3.8073549220576,0.655823707774578,"*",0.499032,"DUX5","GO:0005634//nucleus","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding","GO:0006355//regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter","K09381//paired box protein 3/7;K09332//retina and anterior neural fold homeobox protein","NP_036281.2//double homeobox protein 5 [Homo sapiens]","2//1"]
[83896,614,0.01,0.14,3.8073549220576,0.653672584501845,"*",0.499032,"KRTAP3-1","GO:0005829//cytosol;GO:0045095//keratin filament","GO:0005198//structural molecule activity","GO:0031424//keratinization","NA","NP_114164.1//keratin-associated protein 3-1 [Homo sapiens]","1//3"]
[440021,1149,0.01,0.14,3.8073549220576,0.395265324200913,"*",0.249274,"KRTAP5-2","GO:0005829//cytosol;GO:0045095//keratin filament","NA","GO:0031424//keratinization","K03006//DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]","BAB70862.1//unnamed protein product [Homo sapiens]","1//3"]
[84221,1185,0.01,0.14,3.8073549220576,0.394990861620871,"*",0.249274,"SPATC1L","GO:0005813//centrosome","NA","NA","K17095//annexin A7/11;K20133//USP6 N-terminal-like protein;K21125//mucin-5AC","NP_001136326.1//speriolin-like protein isoform 1 [Homo sapiens]","4;1//3"]
[8646,3527,0.01,0.14,3.8073549220576,0.0380108702238577,"*",0.0155194,"CHRD","GO:0005615//extracellular space","GO:0019955//cytokine binding;GO:0045545//syndecan binding;GO:0008201//heparin binding","GO:0030514//negative regulation of BMP signaling pathway;GO:0001649//osteoblast differentiation;GO:0001702//gastrulation with mouth forming second;GO:0021919//BMP signaling pathway involved in spinal cord dorsal/ventral patterning;GO:0045785//positive regulation of cell adhesion;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0030336//negative regulation of cell migration;GO:0001707//mesoderm formation;GO:0030900//forebrain development;GO:0007275//multicellular organism development;GO:0045668//negative regulation of osteoblast differentiation;GO:0001501//skeletal system development;GO:0033504//floor plate development","K04657//chordin","XP_016862883.1//PREDICTED: chordin isoform X8 [Homo sapiens];NP_003732.2//chordin isoform 1 precursor [Homo sapiens];NP_001291401.1//chordin isoform 2 precursor [Homo sapiens]","1//3;3//A2MP1"]
[219539,1731,0.01,0.14,3.8073549220576,0.226850840374088,"*",0.1245166,"YPEL4","GO:0005730//nucleolus","GO:0046872//metal ion binding","NA","K14697//solute carrier family 30 (zinc transporter), member 10","XP_003464269.2//PREDICTED: protein yippee-like 4 [Cavia porcellus]","2//1"]
[2981,597,0.01,0.14,3.8073549220576,0.649677030806846,"*",0.499032,"GUCA2B","GO:0070062//extracellular exosome;GO:0005576//extracellular region;GO:0001750//photoreceptor outer segment","GO:0030250//guanylate cyclase activator activity;GO:0008048//calcium sensitive guanylate cyclase activator activity","GO:0045776//negative regulation of blood pressure;GO:0006182//cGMP biosynthetic process;GO:0007589//body fluid secretion;GO:0007586//digestion;GO:0007588//excretion","NA","NP_009033.1//guanylate cyclase activator 2B preproprotein [Homo sapiens]","2//1"]
[1576,2789,0.01,0.14,3.8073549220576,0.0703064189261935,"*",0.0310688,"CYP3A4","GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005737//cytoplasm","GO:0050591//quinine 3-monooxygenase activity;GO:0005506//iron ion binding;GO:0047638//albendazole monooxygenase activity;GO:0019825//oxygen binding;GO:0101020//estrogen 16-alpha-hydroxylase activity;GO:0070576//vitamin D 24-hydroxylase activity;GO:0034875//caffeine oxidase activity;GO:0033780//taurochenodeoxycholate 6alpha-hydroxylase activity;GO:0005496//steroid binding;GO:0016491//oxidoreductase activity;GO:0008395//steroid hydroxylase activity;GO:0020037//heme binding;GO:0070330//aromatase activity;GO:0102320//1,8-cineole 2-exo-monooxygenase activity;GO:0004497//monooxygenase activity;GO:0050649//testosterone 6-beta-hydroxylase activity;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0030343//vitamin D3 25-hydroxylase activity;GO:0019899//enzyme binding","GO:0008209//androgen metabolic process;GO:0070989//oxidative demethylation;GO:0016098//monoterpenoid metabolic process;GO:0006805//xenobiotic metabolic process;GO:0046483//heterocycle metabolic process;GO:0055114//oxidation-reduction process;GO:0017144//drug metabolic process;GO:0008202//steroid metabolic process;GO:0006706//steroid catabolic process;GO:0042738//exogenous drug catabolic process;GO:0042737//drug catabolic process;GO:0042359//vitamin D metabolic process;GO:0009822//alkaloid catabolic process;GO:0002933//lipid hydroxylation;GO:0006629//lipid metabolic process","K17691//cytochrome P450 family 3 subfamily A polypeptide 7 [EC:1.14.14.1];K17689//cytochrome P450 family 3 subfamily A polypeptide 4 [EC:1.14.13.32 1.14.13.67 1.14.13.97 1.14.13.157 1.14.13.-]","NP_001189784.1//cytochrome P450 3A4 isoform 2 [Homo sapiens];XP_002817781.1//PREDICTED: cytochrome P450 3A8 isoform X1 [Pongo abelii]","2//1;5"]
[352999,1201,0.01,0.14,3.8073549220576,0.393468663636364,"*",0.249274,"C6orf58","GO:0070062//extracellular exosome;GO:0005615//extracellular space","NA","GO:0007275//multicellular organism development","NA","NP_001010905.1//protein LEG1 homolog precursor [Homo sapiens]","2//1"]
[94086,616,0.01,0.14,3.8073549220576,0.646935332575881,"*",0.499032,"HSPB9","GO:0005634//nucleus;GO:0005737//cytoplasm","NA","NA","K09547//heat shock protein beta-9","NP_149971.1//heat shock protein beta-9 [Homo sapiens]","2//1"]
[346,622,0.01,0.14,3.8073549220576,0.646672926746167,"*",0.499032,"APOC4","GO:0034364//high-density lipoprotein particle;GO:0034361//very-low-density lipoprotein particle;GO:0005576//extracellular region","GO:0005319//lipid transporter activity","GO:0034379//very-low-density lipoprotein particle assembly;GO:0070328//triglyceride homeostasis;GO:0010890//positive regulation of sequestering of triglyceride;GO:0034447//very-low-density lipoprotein particle clearance;GO:0006629//lipid metabolic process","NA","NP_001637.1//apolipoprotein C-IV precursor [Homo sapiens]","2//1"]
[1474,618,0.01,0.14,3.8073549220576,0.645416336167112,"*",0.499032,"CST6","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0001533//cornified envelope","GO:0002020//protease binding;GO:0004869//cysteine-type endopeptidase inhibitor activity","GO:2000117//negative regulation of cysteine-type endopeptidase activity;GO:0008544//epidermis development;GO:0009653//anatomical structure morphogenesis","K13902//cystatin-M","XP_011820624.1//PREDICTED: cystatin-M [Mandrillus leucophaeus]","3//A2MP1"]
[6690,623,0.01,0.14,3.8073549220576,0.639718896396758,"*",0.499032,"SPINK1","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0001669//acrosomal vesicle","GO:0004867//serine-type endopeptidase inhibitor activity;GO:0004866//endopeptidase inhibitor activity","GO:0060046//regulation of acrosome reaction;GO:0010751//negative regulation of nitric oxide mediated signal transduction;GO:0090281//negative regulation of calcium ion import;GO:2001256//regulation of store-operated calcium entry;GO:1900004//negative regulation of serine-type endopeptidase activity;GO:0050732//negative regulation of peptidyl-tyrosine phosphorylation","K06254//agrin","NP_003113.2//serine protease inhibitor Kazal-type 1 precursor [Homo sapiens]","1//3;4"]
[84210,3511,0.02,0.27,3.75488750216347,0.000872475705482555,"Up",2.41086E-4,"ANKRD20A1","GO:0005886//plasma membrane","NA","NA","K17299//POTE ankyrin domain family protein","NP_115626.2//ankyrin repeat domain-containing protein 20A1 [Homo sapiens]","3//A2MP1"]
[3853,2450,0.1,1.34,3.74416109557041,{"v":6.72951186046512e-09,"d":"6.73E-09"},"Up",{"v":8.3329e-10,"d":"8.33E-10"},"KRT6A","GO:0045095//keratin filament","GO:0005198//structural molecule activity","NA","K07605//type II keratin, basic","AAH69269.1//Keratin 6A [Homo sapiens]","3//A2MP1"]
[347168,969,0.01,0.13,3.70043971814109,0.656039599045346,"*",0.499032,"OR1J1","NA","NA","NA","K04257//olfactory receptor","XP_009455506.2//PREDICTED: LOW QUALITY PROTEIN: olfactory receptor 1J1 [Pan troglodytes]","1//3"]
[132851,1233,0.01,0.13,3.70043971814109,0.395658075914149,"*",0.249274,"SPATA4","GO:0005737//cytoplasm","NA","NA","NA","NP_653245.2//spermatogenesis-associated protein 4 [Homo sapiens]","3//A2MP1"]
[2571,2205,0.01,0.13,3.70043971814109,0.227109861657913,"*",0.1245166,"GAD1","NA","NA","NA","K01580//glutamate decarboxylase [EC:4.1.1.15]","XP_012998052.1//PREDICTED: glutamate decarboxylase 1 isoform X1 [Cavia porcellus];XP_008565872.1//PREDICTED: glutamate decarboxylase 1 isoform X1 [Galeopterus variegatus]","3//A2MP1;2//1"]
[57172,2507,0.01,0.13,3.70043971814109,0.127689352525382,"*",0.062198,"CAMK1G","GO:0012505//endomembrane system;GO:0005954//calcium- and calmodulin-dependent protein kinase complex;GO:0005622//intracellular;GO:0005886//plasma membrane;GO:0043005//neuron projection;GO:0000139//Golgi membrane","GO:0005524//ATP binding;GO:0004683//calmodulin-dependent protein kinase activity;GO:0005516//calmodulin binding","GO:0018107//peptidyl-threonine phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0035556//intracellular signal transduction","K08794//calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]","XP_008954847.1//PREDICTED: calcium/calmodulin-dependent protein kinase type 1G isoform X1 [Pan paniscus]","2//1"]
[26740,942,0.01,0.13,3.70043971814109,0.651109790737564,"*",0.499032,"OR1J2","NA","NA","NA","K04257//olfactory receptor","XP_008697025.1//PREDICTED: olfactory receptor 1J2 [Ursus maritimus]","1//3"]
[6698,668,0.01,0.13,3.70043971814109,0.650897131379113,"*",0.499032,"SPRR1A","GO:0005829//cytosol;GO:0001533//cornified envelope;GO:0005737//cytoplasm","GO:0030280//structural constituent of epidermis;GO:0030674//protein binding, bridging;GO:0005198//structural molecule activity","GO:0018149//peptide cross-linking;GO:0008544//epidermis development;GO:0030216//keratinocyte differentiation;GO:0070268//cornification","K08648//hyaluronan binding protein 2 [EC:3.4.21.-];K06826//nidogen (entactin)","NP_005978.2//cornifin-A [Homo sapiens]","1//3;3//A2MP1"]
[644100,642,0.01,0.13,3.70043971814109,0.649571151238592,"*",0.499032,"ARL14EPL","NA","NA","NA","K08343//ubiquitin-like-conjugating enzyme ATG3;K10366//dystrophin","NP_001182510.1//ARL14 effector protein-like [Homo sapiens]","1//3"]
[391123,1818,0.01,0.13,3.70043971814109,0.226695711009802,"*",0.1245166,"VSIG8","GO:0016021//integral component of membrane","NA","NA","K06788//coxsackievirus and adenovirus receptor","NP_001013683.1//V-set and immunoglobulin domain-containing protein 8 precursor [Homo sapiens]","1//3"]
[440955,662,0.01,0.13,3.70043971814109,0.648936597850863,"*",0.499032,"TMEM89","GO:0005634//nucleus;GO:0016021//integral component of membrane","NA","NA","K10447//kelch-like protein 9/13","NP_001008270.1//transmembrane protein 89 precursor [Homo sapiens]","2//1"]
[11012,1206,0.01,0.13,3.70043971814109,0.393041444674761,"*",0.249274,"KLK11","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005794//Golgi apparatus","GO:0004252//serine-type endopeptidase activity;GO:0008236//serine-type peptidase activity","NA","K09620//kallikrein 11 [EC:3.4.21.-]","XP_011524671.1//PREDICTED: kallikrein-11 isoform X1 [Homo sapiens];NP_659196.1//kallikrein-11 isoform 2 [Homo sapiens]","1//3;2//1"]
[7066,1887,0.01,0.13,3.70043971814109,0.226360324160692,"*",0.1245166,"THPO","GO:0005615//extracellular space","GO:0008083//growth factor activity;GO:0005125//cytokine activity;GO:0005179//hormone activity","GO:0051897//positive regulation of protein kinase B signaling;GO:0030099//myeloid cell differentiation;GO:0045654//positive regulation of megakaryocyte differentiation;GO:0038163//thrombopoietin-mediated signaling pathway;GO:1902035//positive regulation of hematopoietic stem cell proliferation;GO:0008283//cell proliferation;GO:0007275//multicellular organism development;GO:0001934//positive regulation of protein phosphorylation;GO:0070374//positive regulation of ERK1 and ERK2 cascade","K06854//thrombopoietin","XP_016797915.1//PREDICTED: thrombopoietin isoform X2 [Pan troglodytes];EAW78244.1//thrombopoietin (myeloproliferative leukemia virus oncogene ligand, megakaryocyte growth and development factor), isoform CRA_b [Homo sapiens];XP_003806645.3//PREDICTED: thrombopoietin isoform X1 [Pan paniscus];XP_008953683.2//PREDICTED: thrombopoietin isoform X2 [Pan paniscus];XP_008953684.2//PREDICTED: thrombopoietin isoform X3 [Pan paniscus];NP_001276932.1//thrombopoietin isoform 5 [Homo sapiens];XP_016797919.1//PREDICTED: thrombopoietin isoform X5 [Pan troglodytes]","1//3;3//A2MP1;2//1"]
[341346,1272,0.01,0.13,3.70043971814109,0.392770060761491,"*",0.249274,"SMCO2","GO:0016021//integral component of membrane","NA","NA","NA","NP_001138482.1//single-pass membrane and coiled-coil domain-containing protein 2 [Homo sapiens]","1//3"]
[3596,1272,0.01,0.13,3.70043971814109,0.392344356685388,"*",0.249274,"IL13","GO:0005615//extracellular space;GO:0009897//external side of plasma membrane;GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0005125//cytokine activity;GO:0005144//interleukin-13 receptor binding","GO:1901215//negative regulation of neuron death;GO:0035094//response to nicotine;GO:0071260//cellular response to mechanical stimulus;GO:0032496//response to lipopolysaccharide;GO:0002639//positive regulation of immunoglobulin production;GO:0045471//response to ethanol;GO:0030890//positive regulation of B cell proliferation;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0071345//cellular response to cytokine stimulus;GO:0001774//microglial cell activation;GO:1901251//positive regulation of lung goblet cell differentiation;GO:0010155//regulation of proton transport;GO:1903660//negative regulation of complement-dependent cytotoxicity;GO:0033861//negative regulation of NAD(P)H oxidase activity;GO:0007165//signal transduction;GO:0043032//positive regulation of macrophage activation;GO:0043306//positive regulation of mast cell degranulation;GO:0007267//cell-cell signaling;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:0006954//inflammatory response;GO:1901247//negative regulation of lung ciliated cell differentiation;GO:0050714//positive regulation of protein secretion;GO:0071635//negative regulation of transforming growth factor beta production;GO:0006928//movement of cell or subcellular component;GO:0032723//positive regulation of connective tissue growth factor production;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0006955//immune response;GO:2000231//positive regulation of pancreatic stellate cell proliferation","K05435//interleukin 13","XP_016800435.1//PREDICTED: interleukin-13 isoform X1 [Pan troglodytes];XP_016809256.1//PREDICTED: interleukin-13 isoform X1 [Pan troglodytes];AAH96141.2//Interleukin 13 [Homo sapiens]","1//3;2//1"]
[6699,641,0.01,0.13,3.70043971814109,0.642140902851619,"*",0.499032,"SPRR1B","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0001533//cornified envelope;GO:0005737//cytoplasm","GO:0030674//protein binding, bridging;GO:0005198//structural molecule activity","GO:0018149//peptide cross-linking;GO:0008544//epidermis development;GO:0030216//keratinocyte differentiation;GO:0070268//cornification","K17602//YLP motif-containing protein 1;K02133//F-type H+-transporting ATPase subunit beta [EC:3.6.3.14]","NP_003116.2//cornifin-B [Homo sapiens]","2//1"]
[3822,1223,0.01,0.13,3.70043971814109,0.391919574409449,"*",0.249274,"KLRC2","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0043235//receptor complex","GO:0030246//carbohydrate binding;GO:1990405//protein antigen binding;GO:0004888//transmembrane signaling receptor activity;GO:0023024//MHC class I protein complex binding","GO:0002228//natural killer cell mediated immunity;GO:0007165//signal transduction;GO:0045087//innate immune response;GO:0006968//cellular defense response","K06541//killer cell lectin-like receptor subfamily C","NP_002251.2//NKG2-C type II integral membrane protein [Homo sapiens]","3//A2MP1"]
[922,1736,0.01,0.13,3.70043971814109,0.391881003444543,"*",0.249274,"CD5L","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0072562//blood microparticle;GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0005044//scavenger receptor activity","GO:0002376//immune system process;GO:0006968//cellular defense response;GO:0006954//inflammatory response;GO:0006915//apoptotic process","K13912//deleted in malignant brain tumors 1 protein","NP_005885.1//CD5 antigen-like isoform 1 precursor [Homo sapiens];NP_001334627.1//CD5 antigen-like isoform 2 precursor [Homo sapiens]","1//3;2//1"]
[344805,2509,0.01,0.13,3.70043971814109,0.127525459119497,"*",0.062198,"TMPRSS7","NA","NA","NA","K09638//transmembrane protease serine 7 [EC:3.4.21.-]","XP_009444420.2//PREDICTED: transmembrane protease serine 7 isoform X1 [Pan troglodytes]","2//1"]
[123346,1210,0.01,0.13,3.70043971814109,0.639205931200385,"*",0.499032,"HIGD2B","GO:0016021//integral component of membrane;GO:0005739//mitochondrion","NA","GO:0097250//mitochondrial respiratory chain supercomplex assembly","K18402//PHD finger protein 20;K09291//nucleoprotein TPR","XP_009248269.1//PREDICTED: LOW QUALITY PROTEIN: putative HIG1 domain family member 2B [Pongo abelii]","1//3"]
[8519,733,0.15,1.92,3.67807190511264,0.000538049712249233,"Up",0.0001427142,"IFITM1","GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005057//signal transducer activity, downstream of receptor","GO:0035456//response to interferon-beta;GO:0060337//type I interferon signaling pathway;GO:0051607//defense response to virus;GO:0046597//negative regulation of viral entry into host cell;GO:0030336//negative regulation of cell migration;GO:0007166//cell surface receptor signaling pathway;GO:0045669//positive regulation of osteoblast differentiation;GO:0001503//ossification;GO:0035455//response to interferon-alpha;GO:0034341//response to interferon-gamma;GO:0045071//negative regulation of viral genome replication;GO:0009615//response to virus;GO:0009607//response to biotic stimulus;GO:0050776//regulation of immune response;GO:0008285//negative regulation of cell proliferation","K19831//interferon induced transmembrane protein 1","NP_003632.3//interferon-induced transmembrane protein 1 [Homo sapiens]","3//A2MP1"]
[84225,2424,0.07,0.89,3.66837850890879,{"v":4.59503892318151e-06,"d":"4.60E-06"},"Up",{"v":8.46288e-07,"d":"8.46E-07"},"ZMYND15","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0042826//histone deacetylase binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0007286//spermatid development","K03006//DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6];K10518//zinc finger and BTB domain-containing protein 47","XP_003315366.2//PREDICTED: zinc finger MYND domain-containing protein 15 isoform X1 [Pan troglodytes];NP_115641.1//zinc finger MYND domain-containing protein 15 isoform 2 [Homo sapiens]","1//3;2//1"]
[145864,2025,5.87,72.96,3.63567332105469,0,"Up",0,"HAPLN3","GO:0005615//extracellular space;GO:0005578//proteinaceous extracellular matrix","GO:0005201//extracellular matrix structural constituent;GO:0005540//hyaluronic acid binding","GO:0007155//cell adhesion;GO:0001501//skeletal system development;GO:0007417//central nervous system development","K06852//hyaluronan and proteoglycan link protein 3","XP_011519563.1//PREDICTED: hyaluronan and proteoglycan link protein 3 isoform X1 [Homo sapiens];NP_001294881.1//hyaluronan and proteoglycan link protein 3 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[389493,682,0.01,0.12,3.58496250072116,0.6540480118149,"*",0.499032,"NUPR2","NA","NA","NA","K09291//nucleoprotein TPR","XP_003896002.2//nuclear protein 2 [Papio anubis]","1//3"]
[972,1322,0.01,0.12,3.58496250072116,0.39522609191067,"*",0.249274,"CD74","GO:0005783//endoplasmic reticulum;GO:0009897//external side of plasma membrane;GO:0030666//endocytic vesicle membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular exosome;GO:0042613//MHC class II protein complex;GO:0005622//intracellular;GO:0005764//lysosome;GO:0005773//vacuole;GO:0009986//cell surface;GO:0035692//macrophage migration inhibitory factor receptor complex;GO:0035693//NOS2-CD74 complex;GO:0005794//Golgi apparatus;GO:0005771//multivesicular body;GO:0012507//ER to Golgi transport vesicle membrane","GO:0035718//macrophage migration inhibitory factor binding;GO:0019955//cytokine binding;GO:0001540//amyloid-beta binding;GO:0004896//cytokine receptor activity;GO:0042658//MHC class II protein binding, via antigen binding groove;GO:0042609//CD4 receptor binding;GO:0042289//MHC class II protein binding;GO:0050998//nitric-oxide synthase binding;GO:0044183//protein binding involved in protein folding","GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0016064//immunoglobulin mediated immune response;GO:0002606//positive regulation of dendritic cell antigen processing and presentation;GO:0045060//negative thymic T cell selection;GO:0030890//positive regulation of B cell proliferation;GO:0045581//negative regulation of T cell differentiation;GO:0001516//prostaglandin biosynthetic process;GO:0002906//negative regulation of mature B cell apoptotic process;GO:0019883//antigen processing and presentation of endogenous antigen;GO:0048146//positive regulation of fibroblast proliferation;GO:0051290//protein heterotetramerization;GO:0046598//positive regulation of viral entry into host cell;GO:0006886//intracellular protein transport;GO:1902166//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0033674//positive regulation of kinase activity;GO:0070206//protein trimerization;GO:0051085//chaperone cofactor-dependent protein refolding;GO:0045893//positive regulation of transcription, DNA-templated;GO:0001961//positive regulation of cytokine-mediated signaling pathway;GO:0043518//negative regulation of DNA damage response, signal transduction by p53 class mediator;GO:0008283//cell proliferation;GO:0045582//positive regulation of T cell differentiation;GO:0060907//positive regulation of macrophage cytokine production;GO:0002792//negative regulation of peptide secretion;GO:0019882//antigen processing and presentation;GO:0000187//activation of MAPK activity;GO:0090023//positive regulation of neutrophil chemotaxis;GO:0035691//macrophage migration inhibitory factor signaling pathway;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0006952//defense response;GO:0002830//positive regulation of type 2 immune response;GO:0006955//immune response;GO:0045657//positive regulation of monocyte differentiation;GO:0045059//positive thymic T cell selection;GO:2000343//positive regulation of chemokine (C-X-C motif) ligand 2 production;GO:0070374//positive regulation of ERK1 and ERK2 cascade","K06505//CD74 antigen","NP_001020329.1//HLA class II histocompatibility antigen gamma chain isoform c [Homo sapiens];NP_004346.1//HLA class II histocompatibility antigen gamma chain isoform b [Homo sapiens];NP_001020330.1//HLA class II histocompatibility antigen gamma chain isoform a [Homo sapiens]","3//A2MP1;2//1"]
[9737,5826,0.01,0.12,3.58496250072116,0.0295116791601718,"*",0.01161512,"GPRASP1","GO:0005829//cytosol","NA","GO:1990172//G-protein coupled receptor catabolic process;GO:0008333//endosome to lysosome transport","K22016//mucin-3/17","NP_055525.3//G-protein coupled receptor-associated sorting protein 1 [Homo sapiens]","4;1//3"]
[165545,2650,0.01,0.12,3.58496250072116,0.12770576503856,"*",0.062198,"DQX1","GO:0005681//spliceosomal complex;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0004004//ATP-dependent RNA helicase activity;GO:0005524//ATP binding","GO:0000398//mRNA splicing, via spliceosome","K14433//ATP-dependent RNA helicase DQX1 [EC:3.6.4.13]","XP_009440984.1//PREDICTED: ATP-dependent RNA helicase DQX1 [Pan troglodytes]","2//1"]
[5653,1486,0.01,0.12,3.58496250072116,0.392576444444444,"*",0.249274,"KLK6","GO:0030141//secretory granule;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005730//nucleolus;GO:0005576//extracellular region;GO:0005739//mitochondrion;GO:0005737//cytoplasm","GO:0004252//serine-type endopeptidase activity","GO:0009611//response to wounding;GO:0042552//myelination;GO:0016540//protein autoprocessing;GO:0042445//hormone metabolic process;GO:0070997//neuron death;GO:0042246//tissue regeneration;GO:0007417//central nervous system development;GO:0045745//positive regulation of G-protein coupled receptor protein signaling pathway;GO:0042982//amyloid precursor protein metabolic process;GO:0010975//regulation of neuron projection development;GO:0045595//regulation of cell differentiation;GO:0030574//collagen catabolic process","K08667//kallikrein 6 [EC:3.4.21.-]","SFW93207.1//TPA: kallikrein I [Homo sapiens];XP_011801672.1//PREDICTED: kallikrein-6 isoform X1 [Colobus angolensis palliatus];XP_010367876.1//PREDICTED: kallikrein-6 isoform X2 [Rhinopithecus roxellana]","1//3;3//A2MP1;2//1"]
[114769,726,0.01,0.12,3.58496250072116,0.642451415860735,"*",0.499032,"CARD16","GO:0097179//protease inhibitor complex;GO:0043234//protein complex","GO:0089720//caspase binding;GO:0050700//CARD domain binding;GO:0042802//identical protein binding;GO:0019900//kinase binding;GO:0004869//cysteine-type endopeptidase inhibitor activity","GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0071456//cellular response to hypoxia;GO:0010804//negative regulation of tumor necrosis factor-mediated signaling pathway;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0031665//negative regulation of lipopolysaccharide-mediated signaling pathway;GO:0050713//negative regulation of interleukin-1 beta secretion;GO:0071222//cellular response to lipopolysaccharide;GO:0071494//cellular response to UV-C;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0032091//negative regulation of protein binding;GO:0097340//inhibition of cysteine-type endopeptidase activity","K12806//caspase recruitment domain-containing protein 16/17/18;K01370//caspase 1 [EC:3.4.22.36]","NP_001017534.1//caspase recruitment domain-containing protein 16 isoform 1 [Homo sapiens]","1//3;2//1"]
[399949,719,0.01,0.12,3.58496250072116,0.641159588836162,"*",0.499032,"C11orf88","NA","NA","NA","K10077//layilin","NP_997313.2//UPF0722 protein C11orf88 isoform 1 [Homo sapiens];NP_001093858.1//UPF0722 protein C11orf88 isoform 2 [Homo sapiens]","1//3;2//1"]
[133060,1946,0.01,0.12,3.58496250072116,0.226077309433962,"*",0.1245166,"OTOP1","GO:0005615//extracellular space;GO:0016021//integral component of membrane","NA","GO:0031214//biomineral tissue development","K21882//PDZ domain-containing protein 7","NP_819056.1//otopetrin-1 [Homo sapiens]","2//1"]
[8637,728,0.51,5.76,3.49749965947082,{"v":3.42318019328226e-10,"d":"3.42E-10"},"Up",{"v":3.63662e-11,"d":"3.64E-11"},"EIF4EBP3","GO:0016020//membrane;GO:0005737//cytoplasm;GO:0016281//eukaryotic translation initiation factor 4F complex","GO:0008190//eukaryotic initiation factor 4E binding;GO:0003743//translation initiation factor activity;GO:0030371//translation repressor activity","GO:0045947//negative regulation of translational initiation","K18645//eukaryotic translation initiation factor 4E binding protein 3","XP_019595811.1//PREDICTED: eukaryotic translation initiation factor 4E-binding protein 3 [Rhinolophus sinicus]","2//1"]
[181,783,0.01,0.11,3.4594316186373,0.655500137159773,"*",0.499032,"AGRP","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0043025//neuronal cell body;GO:0005796//Golgi lumen","GO:0005102//receptor binding;GO:0005184//neuropeptide hormone activity","GO:0007623//circadian rhythm;GO:0060135//maternal process involved in female pregnancy;GO:0032868//response to insulin;GO:0042755//eating behavior;GO:0060259//regulation of feeding behavior;GO:2000253//positive regulation of feeding behavior;GO:0008343//adult feeding behavior;GO:0007631//feeding behavior;GO:0048571//long-day photoperiodism;GO:0007218//neuropeptide signaling pathway;GO:0009755//hormone-mediated signaling pathway","K05231//agouti related protein","NP_001129.1//agouti-related protein precursor [Homo sapiens]","1//3"]
[1071,1537,0.01,0.11,3.4594316186373,0.395304564280751,"*",0.249274,"CETP","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0034364//high-density lipoprotein particle;GO:0005576//extracellular region;GO:0031982//vesicle","GO:0005319//lipid transporter activity;GO:0008289//lipid binding;GO:0031210//phosphatidylcholine binding;GO:0015485//cholesterol binding;GO:0017129//triglyceride binding;GO:0017127//cholesterol transporter activity;GO:0005548//phospholipid transporter activity","GO:0046470//phosphatidylcholine metabolic process;GO:0008203//cholesterol metabolic process;GO:0006869//lipid transport;GO:0034374//low-density lipoprotein particle remodeling;GO:0030301//cholesterol transport;GO:0034372//very-low-density lipoprotein particle remodeling;GO:0070328//triglyceride homeostasis;GO:0015914//phospholipid transport;GO:0042632//cholesterol homeostasis;GO:0055091//phospholipid homeostasis;GO:0010874//regulation of cholesterol efflux;GO:0006641//triglyceride metabolic process;GO:0034197//triglyceride transport;GO:0010745//negative regulation of macrophage derived foam cell differentiation;GO:0034375//high-density lipoprotein particle remodeling;GO:0055088//lipid homeostasis;GO:0043691//reverse cholesterol transport","K16835//cholesteryl ester transfer protein","NP_000069.2//cholesteryl ester transfer protein isoform 1 precursor [Homo sapiens];NP_001273014.1//cholesteryl ester transfer protein isoform 2 precursor [Homo sapiens]","1//3;2//1"]
[3009,790,0.01,0.11,3.4594316186373,0.652869546928747,"*",0.499032,"HIST1H1B","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0000786//nucleosome;GO:0005720//nuclear heterochromatin","GO:0003723//RNA binding;GO:0042826//histone deacetylase binding;GO:0031490//chromatin DNA binding","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006325//chromatin organization;GO:0006334//nucleosome assembly;GO:0030307//positive regulation of cell growth;GO:0050821//protein stabilization;GO:0051574//positive regulation of histone H3-K9 methylation;GO:0071169//establishment of protein localization to chromatin","K11275//histone H1/5","XP_011931511.1//PREDICTED: uncharacterized protein LOC105593202 [Cercocebus atys]","2//1"]
[100653515,2167,0.01,0.11,3.4594316186373,0.227006182195846,"*",0.1245166,"CEP295NL","GO:0031514//motile cilium","NA","NA","K18626//trichohyalin;K13172//serine/arginine repetitive matrix protein 2;K10388//plectin","NP_001230469.1//protein DDC8 homolog isoform 2 [Homo sapiens]","1//3"]
[1504,748,0.01,0.11,3.4594316186373,0.650684610888907,"*",0.499032,"CTRB1","GO:0005615//extracellular space;GO:0005576//extracellular region","GO:0004252//serine-type endopeptidase activity;GO:0008236//serine-type peptidase activity","GO:0022617//extracellular matrix disassembly;GO:0007586//digestion;GO:0009235//cobalamin metabolic process","K01310//chymotrypsin [EC:3.4.21.1]","NP_001897.4//chymotrypsinogen B isoform 1 precursor [Homo sapiens];NP_001316119.1//chymotrypsinogen B isoform 2 precursor [Homo sapiens]","1//3;5"]
[266675,2096,0.01,0.11,3.4594316186373,0.226592409250399,"*",0.1245166,"BEST4","GO:0034707//chloride channel complex;GO:0005886//plasma membrane","GO:0005254//chloride channel activity","NA","K13881//bestrophin-4","XP_021796530.1//bestrophin-4 isoform X1 [Papio anubis]","2//1"]
[5672,1829,0.01,0.11,3.4594316186373,0.226463414368667,"*",0.1245166,"PSG4","GO:0070062//extracellular exosome","NA","GO:0007565//female pregnancy","K06500//pregnancy specific beta-1-glycoprotein","NP_001263424.1//pregnancy-specific beta-1-glycoprotein 4 isoform 3 precursor [Homo sapiens];NP_001303268.1//pregnancy-specific beta-1-glycoprotein 4 isoform 4 [Homo sapiens];NP_002771.2//pregnancy-specific beta-1-glycoprotein 4 isoform 1 precursor [Homo sapiens];XP_009230948.1//PREDICTED: pregnancy-specific beta-1-glycoprotein 2-like isoform X2 [Pongo abelii]","1//3;4;2//1"]
[29986,1413,0.01,0.11,3.4594316186373,0.393119051831375,"*",0.249274,"SLC39A2","GO:0005887//integral component of plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005385//zinc ion transmembrane transporter activity","GO:0006829//zinc II ion transport;GO:0071577//zinc II ion transmembrane transport","K14709//solute carrier family 39 (zinc transporter), member 1/2/3","NP_055394.2//zinc transporter ZIP2 isoform a [Homo sapiens]","1//3;3//A2MP1"]
[56660,1449,0.01,0.11,3.4594316186373,0.393002652585867,"*",0.249274,"KCNK12","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane","GO:0005244//voltage-gated ion channel activity;GO:0005267//potassium channel activity;GO:0022841//potassium ion leak channel activity","GO:0030322//stabilization of membrane potential;GO:0071805//potassium ion transmembrane transport","K04921//potassium channel subfamily K member 12","NP_071338.1//potassium channel subfamily K member 12 [Homo sapiens]","1//3"]
[389812,762,0.01,0.11,3.4594316186373,0.645939321610891,"*",0.499032,"LCN15","GO:0005576//extracellular region","GO:0005215//transporter activity;GO:0036094//small molecule binding","GO:0006629//lipid metabolic process","K01830//prostaglandin-H2 D-isomerase [EC:5.3.99.2]","NP_976222.1//lipocalin-15 precursor [Homo sapiens]","1//3"]
[89886,761,0.01,0.11,3.4594316186373,0.645259605633803,"*",0.499032,"SLAMF9","GO:0016021//integral component of membrane","NA","NA","K06570//lymphocyte antigen 9;K06511//CD84 antigen","NP_001139645.1//SLAM family member 9 isoform 3 precursor [Homo sapiens];NP_001139644.1//SLAM family member 9 isoform 2 precursor [Homo sapiens];NP_254273.2//SLAM family member 9 isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[3007,777,0.01,0.11,3.4594316186373,0.643021470355731,"*",0.499032,"HIST1H1D","GO:0005719//nuclear euchromatin;GO:0000790//nuclear chromatin;GO:0000786//nucleosome","GO:0003723//RNA binding;GO:0031490//chromatin DNA binding","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0098532//histone H3-K27 trimethylation;GO:0006334//nucleosome assembly;GO:0080182//histone H3-K4 trimethylation;GO:0016584//nucleosome positioning","K11275//histone H1/5","NP_005311.1//histone H1.3 [Homo sapiens]","2//1"]
[6866,787,0.01,0.11,3.4594316186373,0.641934060879369,"*",0.499032,"TAC3","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005576//extracellular region","GO:0031837//substance K receptor binding;GO:0031836//neuromedin K receptor binding;GO:0005102//receptor binding","GO:0007565//female pregnancy;GO:0007217//tachykinin receptor signaling pathway;GO:1902093//positive regulation of flagellated sperm motility;GO:0007218//neuropeptide signaling pathway","K05240//tachykinin 2/3","NP_037383.1//tachykinin-3 isoform 1 preproprotein [Homo sapiens];NP_001171525.1//tachykinin-3 isoform 2 precursor [Homo sapiens]","1//3;3//A2MP1"]
[79413,2226,0.01,0.11,3.4594316186373,0.226103008798454,"*",0.1245166,"ZBED2","NA","GO:0046872//metal ion binding;GO:0003677//DNA binding","NA","K06517//CD96 antigen","NP_078784.2//zinc finger BED domain-containing protein 2 [Homo sapiens]",4]
[405753,1451,0.01,0.11,3.4594316186373,0.391958152967812,"*",0.249274,"DUOXA2","GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","NA","GO:0050727//regulation of inflammatory response;GO:2000609//regulation of thyroid hormone generation;GO:0042743//hydrogen peroxide metabolic process;GO:0015031//protein transport","K17232//dual oxidase maturation factor 2","NP_997464.2//dual oxidase maturation factor 2 [Homo sapiens]","3//A2MP1"]
[6890,2656,8.92,96.68,3.43810185784528,0,"Up",0,"TAP1","GO:0005815//microtubule organizing center;GO:0042825//TAP complex;GO:0005739//mitochondrion","GO:0043531//ADP binding;GO:0015440//peptide-transporting ATPase activity;GO:0005524//ATP binding;GO:0046979//TAP2 binding;GO:0023029//MHC class Ib protein binding;GO:0042288//MHC class I protein binding","GO:0046967//cytosol to ER transport;GO:0006952//defense response;GO:0019885//antigen processing and presentation of endogenous peptide antigen via MHC class I","K05653//ATP-binding cassette, subfamily B (MDR/TAP), member 2","XP_012358659.1//PREDICTED: antigen peptide transporter 1 isoform X2 [Nomascus leucogenys];BAG36500.1//unnamed protein product [Homo sapiens]","1//3;5"]
[5698,1048,2.82,29.55,3.3893910626661,{"v":3.88023187801418e-71,"d":"3.88E-71"},"Up",{"v":3.42502e-73,"d":"3.43E-73"},"PSMB9","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000502//proteasome complex;GO:1990111//spermatoproteasome complex;GO:0005737//cytoplasm;GO:0005839//proteasome core complex;GO:0005829//cytosol;GO:0019774//proteasome core complex, beta-subunit complex","GO:0004298//threonine-type endopeptidase activity","GO:0043687//post-translational protein modification;GO:0038061//NIK/NF-kappaB signaling;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0006521//regulation of cellular amino acid metabolic process;GO:2000116//regulation of cysteine-type endopeptidase activity;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0016579//protein deubiquitination;GO:0043488//regulation of mRNA stability;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0000209//protein polyubiquitination;GO:0055085//transmembrane transport;GO:0000165//MAPK cascade;GO:0050852//T cell receptor signaling pathway;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0016032//viral process;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:1902036//regulation of hematopoietic stem cell differentiation","K02741//20S proteasome subunit beta 9 [EC:3.4.25.1]","NP_002791.1//proteasome subunit beta type-9 precursor [Homo sapiens]",4]
[23764,2269,3.8,39.79,3.38833457536279,{"v":5.10230491448276e-214,"d":"5.10E-214"},"Up",{"v":9.26297999999999e-217,"d":"9.26E-217"},"MAFF","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion","GO:0003677//DNA binding;GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0007596//blood coagulation;GO:0006351//transcription, DNA-templated;GO:0001701//in utero embryonic development;GO:0006366//transcription from RNA polymerase II promoter;GO:0035914//skeletal muscle cell differentiation;GO:0007567//parturition;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045604//regulation of epidermal cell differentiation","K09037//transcription factor MAFF/G/K","NP_036455.1//transcription factor MafF isoform a [Homo sapiens];XP_011834265.1//PREDICTED: transcription factor MafF isoform X1 [Mandrillus leucophaeus];XP_011819623.1//PREDICTED: transcription factor MafF isoform X1 [Colobus angolensis palliatus]","1//3;3//A2MP1"]
[29802,602,0.14,1.42,3.34239219744708,0.0170814726913916,"*",0.00628552,"VPREB3","GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005576//extracellular region","NA","GO:0050900//leukocyte migration;GO:0002377//immunoglobulin production;GO:0006955//immune response","K06553//pre-B lymphocyte gene","NP_037510.1//pre-B lymphocyte protein 3 precursor [Homo sapiens]","2//1"]
[554235,865,0.01,0.1,3.32192809488736,0.65576975715696,"*",0.499032,"ASPDH","NA","GO:0050661//NADP binding;GO:0033735//aspartate dehydrogenase activity","GO:0006742//NADP catabolic process;GO:0009435//NAD biosynthetic process","K16360//netrin-G3 ligand;K15235//josephin [EC:3.4.19.12]","XP_524347.3//PREDICTED: putative L-aspartate dehydrogenase isoform X1 [Pan troglodytes];NP_001019827.2//putative L-aspartate dehydrogenase isoform 2 [Homo sapiens]","1//3;2//1"]
[4102,1753,0.01,0.1,3.32192809488736,0.394560332540626,"*",0.249274,"MAGEA3","GO:0005783//endoplasmic reticulum","GO:0089720//caspase binding","GO:0010955//negative regulation of protein processing;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:1902236//negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway","K12464//melanoma-associated antigen D1","NP_005353.1//melanoma-associated antigen 3 [Homo sapiens]","3//A2MP1"]
[132946,836,0.01,0.1,3.32192809488736,0.651216172534924,"*",0.499032,"ARL9","NA","NA","NA","K07957//ADP-ribosylation factor-like protein 9","Q6T311.1//RecName: Full=ADP-ribosylation factor-like protein 9","1//3"]
[388125,1576,0.01,0.1,3.32192809488736,0.394482155339806,"*",0.249274,"C2CD4B","GO:0005634//nucleus;GO:0005886//plasma membrane","GO:0005544//calcium-dependent phospholipid binding;GO:0005509//calcium ion binding","NA","K16628//collagen, type VII, alpha","NP_001007596.2//C2 calcium-dependent domain-containing protein 4B [Homo sapiens]","2//1"]
[388551,1692,0.01,0.1,3.32192809488736,0.39440400911252,"*",0.249274,"CEACAM16","GO:0005615//extracellular space;GO:0032426//stereocilium tip","GO:0042802//identical protein binding","GO:0007605//sensory perception of sound","K06499//carcinoembryonic antigen-related cell adhesion molecule","AAQ05841.1//carcinoembryonic antigen like-2 protein [Homo sapiens]","3//A2MP1"]
[148545,2499,0.01,0.1,3.32192809488736,0.22679910700114,"*",0.1245166,"NBPF4","GO:0005737//cytoplasm","NA","NA","K22244//regenerating islet-derived protein 4;K16549//myomegalin","XP_005271201.1//PREDICTED: neuroblastoma breakpoint family member 6 isoform X1 [Homo sapiens]","2//1"]
[3046,816,0.01,0.1,3.32192809488736,0.650153916320039,"*",0.499032,"HBE1","GO:0072562//blood microparticle;GO:0005829//cytosol;GO:0005833//hemoglobin complex","GO:0020037//heme binding;GO:0005506//iron ion binding;GO:0005344//oxygen carrier activity;GO:0019825//oxygen binding;GO:0031721//hemoglobin alpha binding","GO:0051291//protein heterooligomerization;GO:0014070//response to organic cyclic compound;GO:0007596//blood coagulation","K13825//hemoglobin subunit epsilon","XP_002822172.1//PREDICTED: hemoglobin subunit epsilon [Pongo abelii]","3//A2MP1"]
[7062,6995,0.01,0.1,3.32192809488736,0.029506985826972,"*",0.01161512,"TCHH","GO:0005856//cytoskeleton;GO:0005829//cytosol;GO:0001533//cornified envelope","GO:0005509//calcium ion binding;GO:0046914//transition metal ion binding","GO:0070268//cornification","K18626//trichohyalin","NP_009044.2//trichohyalin [Homo sapiens]","3//A2MP1"]
[4689,1551,0.01,0.1,3.32192809488736,0.393818897834042,"*",0.249274,"NCF4","GO:0032010//phagolysosome;GO:0016020//membrane;GO:0010008//endosome membrane;GO:0043020//NADPH oxidase complex;GO:0005829//cytosol;GO:0005802//trans-Golgi network","GO:0016176//superoxide-generating NADPH oxidase activator activity;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0005086//ARF guanyl-nucleotide exchange factor activity;GO:0046983//protein dimerization activity","GO:0055114//oxidation-reduction process;GO:0016192//vesicle-mediated transport;GO:0045730//respiratory burst;GO:0045454//cell redox homeostasis;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0034599//cellular response to oxidative stress;GO:0006955//immune response;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0006909//phagocytosis","K08012//neutrophil cytosolic factor 4","NP_038202.2//neutrophil cytosol factor 4 isoform 2 [Homo sapiens];NP_000622.2//neutrophil cytosol factor 4 isoform 1 [Homo sapiens]","4;3//A2MP1"]
[56287,820,0.01,0.1,3.32192809488736,0.646725390881064,"*",0.499032,"GKN1","GO:0005615//extracellular space","NA","GO:0007586//digestion;GO:0042127//regulation of cell proliferation;GO:0051781//positive regulation of cell division","K20909//anthrax toxin receptor","NP_062563.3//gastrokine-1 [Homo sapiens]","3//A2MP1"]
[169355,2294,0.01,0.1,3.32192809488736,0.226437633014572,"*",0.1245166,"IDO2","GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0020037//heme binding;GO:0033754//indoleamine 2,3-dioxygenase activity;GO:0004833//tryptophan 2,3-dioxygenase activity","GO:0002376//immune system process;GO:0006569//tryptophan catabolic process;GO:0019441//tryptophan catabolic process to kynurenine","K00463//indoleamine 2,3-dioxygenase [EC:1.13.11.52]","NP_919270.2//indoleamine 2,3-dioxygenase 2 [Homo sapiens]","2//1"]
[4635,855,0.01,0.1,3.32192809488736,0.646620471122648,"*",0.499032,"MYL4","NA","NA","NA","K12750//myosin light chain 4","XP_004374303.1//PREDICTED: myosin light chain 4 [Trichechus manatus latirostris];XP_017738431.1//PREDICTED: myosin light chain 4 isoform X1 [Rhinopithecus bieti]","1//3;2//1"]
[10278,3082,0.01,0.1,3.32192809488736,0.127574582948125,"*",0.062198,"EFS","GO:0005737//cytoplasm","GO:0019904//protein domain specific binding;GO:0017124//SH3 domain binding","GO:0007155//cell adhesion;GO:0035556//intracellular signal transduction","K05726//breast cancer anti-estrogen resistance 1","NP_005855.1//embryonal Fyn-associated substrate isoform 1 [Homo sapiens];NP_001264103.1//embryonal Fyn-associated substrate isoform 3 [Homo sapiens];NP_115835.1//embryonal Fyn-associated substrate isoform 2 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[9992,809,0.01,0.1,3.32192809488736,0.64385244875212,"*",0.499032,"KCNE2","GO:0005783//endoplasmic reticulum;GO:0009986//cell surface;GO:0005794//Golgi apparatus;GO:0005764//lysosome;GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex","GO:0044325//ion channel binding;GO:0015459//potassium channel regulator activity;GO:0005242//inward rectifier potassium channel activity;GO:1902282//voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization;GO:0005251//delayed rectifier potassium channel activity;GO:0042803//protein homodimerization activity","GO:1902260//negative regulation of delayed rectifier potassium channel activity;GO:0086009//membrane repolarization;GO:0035690//cellular response to drug;GO:1901379//regulation of potassium ion transmembrane transport;GO:1901800//positive regulation of proteasomal protein catabolic process;GO:1902259//regulation of delayed rectifier potassium channel activity;GO:0071435//potassium ion export;GO:1901979//regulation of inward rectifier potassium channel activity;GO:0060307//regulation of ventricular cardiac muscle cell membrane repolarization;GO:0086005//ventricular cardiac muscle cell action potential;GO:0061337//cardiac conduction;GO:1901387//positive regulation of voltage-gated calcium channel activity;GO:1902159//regulation of cyclic nucleotide-gated ion channel activity;GO:0086091//regulation of heart rate by cardiac conduction;GO:0086002//cardiac muscle cell action potential involved in contraction;GO:0007568//aging;GO:0010107//potassium ion import;GO:0043586//tongue development;GO:0098915//membrane repolarization during ventricular cardiac muscle cell action potential;GO:0060306//regulation of membrane repolarization;GO:0086011//membrane repolarization during action potential;GO:0071805//potassium ion transmembrane transport","K04896//potassium voltage-gated channel Isk-related subfamily E member 2","XP_018873175.1//PREDICTED: potassium voltage-gated channel subfamily E member 2 isoform X1 [Gorilla gorilla gorilla]","1//3"]
[474354,1642,0.01,0.1,3.32192809488736,0.392228415681639,"*",0.249274,"LRRC18","GO:0005737//cytoplasm","NA","GO:0007165//signal transduction","K10130//leucine-rich repeats and death domain-containing protein","NP_001006940.3//leucine-rich repeat-containing protein 18 [Homo sapiens]","3//A2MP1"]
[646951,819,0.01,0.1,3.32192809488736,0.641830689855072,"*",0.499032,"MINDY4B","NA","NA","NA","K08742//E3 ubiquitin-protein ligase SIAH2 [EC:2.3.2.27]","XP_016863110.1//PREDICTED: protein FAM188B2 [Homo sapiens]","1//3"]
[4118,859,0.01,0.1,3.32192809488736,0.640232685567424,"*",0.499032,"MAL","GO:0005783//endoplasmic reticulum;GO:0045121//membrane raft;GO:0016324//apical plasma membrane;GO:0019898//extrinsic component of membrane;GO:0016021//integral component of membrane","GO:0008289//lipid binding;GO:0016505//peptidase activator activity involved in apoptotic process;GO:0019911//structural constituent of myelin sheath","GO:0042552//myelination;GO:1902043//positive regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0001766//membrane raft polarization;GO:0030154//cell differentiation;GO:0008104//protein localization;GO:0007417//central nervous system development;GO:0006915//apoptotic process;GO:0045176//apical protein localization","NA","EAX10707.1//mal, T-cell differentiation protein, isoform CRA_b [Homo sapiens];NP_002362.1//myelin and lymphocyte protein isoform a [Homo sapiens]","3//A2MP1;2//1"]
[3567,816,0.01,0.1,3.32192809488736,0.639154679923028,"*",0.499032,"IL5","GO:0005615//extracellular space;GO:0005622//intracellular;GO:0005576//extracellular region","GO:0004713//protein tyrosine kinase activity;GO:0005137//interleukin-5 receptor binding;GO:0008083//growth factor activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005125//cytokine activity","GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0000165//MAPK cascade;GO:0071803//positive regulation of podosome assembly;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006954//inflammatory response;GO:0030890//positive regulation of B cell proliferation;GO:0046427//positive regulation of JAK-STAT cascade;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0051024//positive regulation of immunoglobulin secretion;GO:0045645//positive regulation of eosinophil differentiation;GO:0006955//immune response;GO:0019221//cytokine-mediated signaling pathway","K05428//interleukin 5","XP_005272045.1//PREDICTED: interleukin-5 isoform X1 [Homo sapiens]","2//1"]
[710,1832,0.31,3.07,3.3078985349833,{"v":2.29756963610451e-13,"d":"2.30E-13"},"Up",{"v":1.816596e-14,"d":"1.82E-14"},"SERPING1","GO:0031093//platelet alpha granule lumen;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0072562//blood microparticle;GO:0005576//extracellular region","GO:0004867//serine-type endopeptidase inhibitor activity","GO:0042730//fibrinolysis;GO:0030449//regulation of complement activation;GO:0007597//blood coagulation, intrinsic pathway;GO:0007568//aging;GO:0030193//regulation of blood coagulation;GO:0008015//blood circulation;GO:0006958//complement activation, classical pathway;GO:0001869//negative regulation of complement activation, lectin pathway;GO:0045916//negative regulation of complement activation;GO:0002576//platelet degranulation;GO:0045087//innate immune response","K04001//C1 inhibitor","BAD93063.1//Plasma protease C1 inhibitor precursor variant, partial [Homo sapiens]","1//3;2//1"]
[22977,1301,0.07,0.68,3.28010791919274,0.0170756626666667,"*",0.00628552,"AKR7A3","GO:0070062//extracellular exosome;GO:0005829//cytosol","GO:0009055//electron transfer activity;GO:0042802//identical protein binding;GO:0004033//aldo-keto reductase (NADP) activity","GO:0006081//cellular aldehyde metabolic process;GO:0006805//xenobiotic metabolic process","K15303//aflatoxin B1 aldehyde reductase","NP_036199.2//aflatoxin B1 aldehyde reductase member 3 [Homo sapiens]","2//1"]
[647219,1420,0.06,0.57,3.24792751344359,0.0170785671848954,"*",0.00628552,"ASCL5","NA","GO:0003677//DNA binding;GO:0046983//protein dimerization activity","NA","K09067//achaete-scute complex protein","Q7RTU5.2//RecName: Full=Achaete-scute homolog 5; Short=ASH-5; Short=hASH5; AltName: Full=Class A basic helix-loop-helix protein 47; Short=bHLHa47","1//3"]
[6398,2282,0.28,2.56,3.1926450779424,{"v":1.96763757607656e-13,"d":"1.97E-13"},"Up",{"v":1.544646E-14,"d":"1.54E-14"},"SECTM1","NA","NA","NA","K06457//T-cell surface glycoprotein CD7;K22020//mucin-19","XP_012358039.1//PREDICTED: LOW QUALITY PROTEIN: secreted and transmembrane protein 1 [Nomascus leucogenys]","2//1"]
[29970,1848,0.47,4.27,3.18350340794285,{"v":2.83145216075949e-17,"d":"2.83E-17"},"Up",{"v":1.680366E-18,"d":"1.68E-18"},"SCHIP1","NA","GO:0042802//identical protein binding","NA","K19475//WAS/WASL-interacting protein;K05747//Wiskott-Aldrich syndrome protein;K21125//mucin-5AC;K16882//protein piccolo","NP_001184036.1//schwannomin-interacting protein 1 isoform 2 [Homo sapiens];NP_055390.1//schwannomin-interacting protein 1 isoform 1 [Homo sapiens];NP_001184037.1//schwannomin-interacting protein 1 isoform 3 [Homo sapiens];EDL15509.1//schwannomin interacting protein 1, partial [Mus musculus]","1//3;3//A2MP1"]
[401409,952,0.01,0.09,3.16992500144231,0.656093594074074,"*",0.499032,"RAB19","GO:0070062//extracellular exosome;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane","GO:0005525//GTP binding;GO:0003924//GTPase activity","NA","K17047//Ras-related protein Rab-19","NP_001008749.2//ras-related protein Rab-19 [Homo sapiens]","2//1"]
[926,944,0.01,0.09,3.16992500144231,0.654800161655988,"*",0.499032,"CD8B","GO:0042101//T cell receptor complex;GO:0031901//early endosome membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0042288//MHC class I protein binding;GO:0015026//coreceptor activity","GO:0042110//T cell activation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0050690//regulation of defense response to virus by virus;GO:0006955//immune response;GO:0050776//regulation of immune response;GO:0002250//adaptive immune response","K06459//T-cell surface glycoprotein CD8 beta chain","NP_757362.1//T-cell surface glycoprotein CD8 beta chain isoform 2 precursor [Homo sapiens];NP_742100.1//T-cell surface glycoprotein CD8 beta chain isoform 4 precursor [Homo sapiens];NP_001171571.1//T-cell surface glycoprotein CD8 beta chain isoform 6 precursor [Homo sapiens];NP_004922.1//T-cell surface glycoprotein CD8 beta chain isoform 5 precursor [Homo sapiens]","4;1//3;3//A2MP1"]
[9087,1702,0.01,0.09,3.16992500144231,0.395422331281033,"*",0.249274,"TMSB4Y","GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0005829//cytosol","GO:0003785//actin monomer binding","GO:0008064//regulation of actin polymerization or depolymerization;GO:0007015//actin filament organization;GO:0030334//regulation of cell migration;GO:0042989//sequestering of actin monomers","K05764//thymosin, beta 4","EAW91614.1//thymosin, beta 4, Y-linked, partial [Homo sapiens]","2//1"]
[23428,3448,0.03,0.27,3.16992500144231,0.00555591868998655,"*",1.809656E-3,"SLC7A8","GO:0070062//extracellular exosome;GO:0016323//basolateral plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0019534//toxin transmembrane transporter activity;GO:0015175//neutral amino acid transmembrane transporter activity;GO:0042605//peptide antigen binding;GO:0015101//organic cation transmembrane transporter activity;GO:0015179//L-amino acid transmembrane transporter activity;GO:0015297//antiporter activity;GO:0015171//amino acid transmembrane transporter activity","GO:0006810//transport;GO:0055065//metal ion homeostasis;GO:0006865//amino acid transport;GO:0050900//leukocyte migration;GO:0006520//cellular amino acid metabolic process;GO:0015804//neutral amino acid transport;GO:0009636//response to toxic substance","K13781//solute carrier family 7 (L-type amino acid transporter), member 8","CAD62616.1//unnamed protein product, partial [Homo sapiens];NP_001253966.1//large neutral amino acids transporter small subunit 2 isoform d [Homo sapiens];XP_010376698.1//PREDICTED: large neutral amino acids transporter small subunit 2 isoform X1 [Rhinopithecus roxellana];NP_001253965.1//large neutral amino acids transporter small subunit 2 isoform c [Homo sapiens]","1//3;3//A2MP1;2//1"]
[26693,948,0.01,0.09,3.16992500144231,0.651695321124918,"*",0.499032,"OR2V1","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity","NA","K04257//olfactory receptor","XP_003900702.1//olfactory receptor 2V1-like [Papio anubis]","1//3"]
[8843,2152,0.01,0.09,3.16992500144231,0.394638540733399,"*",0.249274,"HCAR3","GO:0005887//integral component of plasma membrane;GO:0030054//cell junction;GO:0005886//plasma membrane","GO:0004930//G-protein coupled receptor activity","GO:0007186//G-protein coupled receptor signaling pathway","K08402//G protein-coupled receptor 109","NP_006009.2//hydroxycarboxylic acid receptor 3 [Homo sapiens]","2//1"]
[285051,891,0.01,0.09,3.16992500144231,0.650737728,"*",0.499032,"STPG4","GO:0005634//nucleus;GO:0001939//female pronucleus;GO:0042585//germinal vesicle;GO:0001940//male pronucleus;GO:0005737//cytoplasm","GO:0003682//chromatin binding","GO:0016569//covalent chromatin modification;GO:1901537//positive regulation of DNA demethylation;GO:0044727//DNA demethylation of male pronucleus","NA","NP_775920.1//protein STPG4 isoform 2 [Homo sapiens];NP_001157033.1//protein STPG4 isoform 1 [Homo sapiens]","1//3;2//1"]
[2348,962,0.01,0.09,3.16992500144231,0.650206946818923,"*",0.499032,"FOLR1","GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0031526//brush border membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0000139//Golgi membrane;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0046658//anchored component of plasma membrane;GO:0005886//plasma membrane;GO:0070062//extracellular exosome;GO:0031362//anchored component of external side of plasma membrane;GO:0005634//nucleus;GO:0030136//clathrin-coated vesicle;GO:0005768//endosome;GO:0009986//cell surface;GO:0030133//transport vesicle;GO:0005789//endoplasmic reticulum membrane;GO:0012507//ER to Golgi transport vesicle membrane","GO:0005542//folic acid binding;GO:0051870//methotrexate binding;GO:0004872//receptor activity;GO:0008517//folic acid transmembrane transporter activity;GO:0008144//drug binding;GO:0061714//folic acid receptor activity","GO:0031103//axon regeneration;GO:0071231//cellular response to folic acid;GO:0061626//pharyngeal arch artery morphogenesis;GO:0015884//folic acid transport;GO:0061713//anterior neural tube closure;GO:0048208//COPII vesicle coating;GO:0017015//regulation of transforming growth factor beta receptor signaling pathway;GO:0001947//heart looping;GO:0060828//regulation of canonical Wnt signaling pathway;GO:0006898//receptor-mediated endocytosis;GO:0003147//neural crest cell migration involved in heart formation;GO:0003253//cardiac neural crest cell migration involved in outflow tract morphogenesis;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0046655//folic acid metabolic process","K13649//folate receptor","NP_000793.1//folate receptor alpha precursor [Homo sapiens]","3//A2MP1;2//1"]
[1193,2694,0.01,0.09,3.16992500144231,0.226540793667426,"*",0.1245166,"CLIC2","GO:0005634//nucleus;GO:0005622//intracellular;GO:0034707//chloride channel complex;GO:0005737//cytoplasm","GO:0005244//voltage-gated ion channel activity;GO:0004602//glutathione peroxidase activity;GO:0005254//chloride channel activity","GO:0006810//transport;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0007165//signal transduction;GO:0010881//regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion;GO:0051099//positive regulation of binding;GO:0060315//negative regulation of ryanodine-sensitive calcium-release channel activity;GO:1902476//chloride transmembrane transport","K05022//chloride intracellular channel protein 2","NP_001280.3//chloride intracellular channel protein 2 [Homo sapiens]",5]
[29949,1848,0.01,0.09,3.16992500144231,0.393390918395574,"*",0.249274,"IL19","GO:0005615//extracellular space;GO:0005576//extracellular region","GO:0005125//cytokine activity","GO:0007165//signal transduction;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:0006955//immune response;GO:0072593//reactive oxygen species metabolic process;GO:0042226//interleukin-6 biosynthetic process;GO:0006915//apoptotic process","K05444//interleukin 19/20/24","NP_715639.1//interleukin-19 isoform 1 [Homo sapiens]","3//A2MP1;2//1"]
[137735,2831,0.01,0.09,3.16992500144231,0.22648920159417,"*",0.1245166,"ABRA","GO:0015629//actin cytoskeleton;GO:0030016//myofibril;GO:0030017//sarcomere;GO:0005886//plasma membrane","GO:0003779//actin binding","GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0035025//positive regulation of Rho protein signal transduction;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0000060//protein import into nucleus, translocation","K09291//nucleoprotein TPR","NP_631905.1//actin-binding Rho-activating protein [Homo sapiens]",4]
[3816,886,0.01,0.09,3.16992500144231,0.645102951201748,"*",0.499032,"KLK1","GO:0070062//extracellular exosome;GO:0005634//nucleus","GO:0004252//serine-type endopeptidase activity","NA","K01325//tissue kallikrein [EC:3.4.21.35]","NP_002248.1//kallikrein-1 preproprotein [Homo sapiens]","3//A2MP1"]
[338382,2955,0.06,0.54,3.16992500144231,0.000455418969621466,"Up",0.0001190008,"RAB7B","GO:0045335//phagocytic vesicle;GO:0005770//late endosome;GO:0005794//Golgi apparatus;GO:0031902//late endosome membrane;GO:0030670//phagocytic vesicle membrane;GO:0005764//lysosome;GO:0005802//trans-Golgi network","GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0032755//positive regulation of interleukin-6 production;GO:0034499//late endosome to Golgi transport;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0034144//negative regulation of toll-like receptor 4 signaling pathway;GO:0045654//positive regulation of megakaryocyte differentiation;GO:0034164//negative regulation of toll-like receptor 9 signaling pathway;GO:0015031//protein transport;GO:0061024//membrane organization","K07898//Ras-related protein Rab-7B","XP_014925443.1//PREDICTED: ras-related protein Rab-7b [Acinonyx jubatus];NP_001291768.1//ras-related protein Rab-7b isoform b [Homo sapiens]","1//3;2//1;5"]
[79541,1758,0.01,0.09,3.16992500144231,0.392537744085174,"*",0.249274,"OR2A4","NA","NA","NA","K04257//olfactory receptor","XP_012367550.1//PREDICTED: LOW QUALITY PROTEIN: olfactory receptor 2A7 [Nomascus leucogenys]","2//1"]
[29118,1967,0.01,0.09,3.16992500144231,0.392267055068466,"*",0.249274,"DDX25","GO:0005634//nucleus;GO:0033391//chromatoid body","GO:0004004//ATP-dependent RNA helicase activity;GO:0005524//ATP binding;GO:0003676//nucleic acid binding","GO:0006406//mRNA export from nucleus;GO:0007286//spermatid development;GO:0006417//regulation of translation","K18656//ATP-dependent RNA helicase DDX25 [EC:3.6.4.13]","XP_003923580.1//PREDICTED: ATP-dependent RNA helicase DDX25 [Saimiri boliviensis boliviensis]","1//3;4"]
[4935,1711,0.01,0.09,3.16992500144231,0.392189783906235,"*",0.249274,"GPR143","GO:0016020//membrane;GO:0005765//lysosomal membrane;GO:0016324//apical plasma membrane;GO:0033162//melanosome membrane;GO:0042470//melanosome;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0072544//L-DOPA binding;GO:0035643//L-DOPA receptor activity;GO:0072545//tyrosine binding;GO:0035240//dopamine binding;GO:0004930//G-protein coupled receptor activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0007165//signal transduction;GO:0007601//visual perception;GO:0035584//calcium-mediated signaling using intracellular calcium source;GO:0032400//melanosome localization;GO:1903056//regulation of melanosome organization;GO:0032402//melanosome transport;GO:1902908//regulation of melanosome transport;GO:0050848//regulation of calcium-mediated signaling;GO:0006726//eye pigment biosynthetic process;GO:0048015//phosphatidylinositol-mediated signaling;GO:0032438//melanosome organization","K08470//Ocular albinism type 1 protein","CAA88742.1//OA1 [Homo sapiens]","2//1"]
[255798,1812,0.01,0.09,3.16992500144231,0.392151159740004,"*",0.249274,"SMCO1","GO:0016021//integral component of membrane","NA","NA","NA","NP_001307402.1//single-pass membrane and coiled-coil domain-containing protein 1 isoform 2 [Homo sapiens];NP_001071125.1//single-pass membrane and coiled-coil domain-containing protein 1 isoform 1 [Homo sapiens]","1//3;2//1"]
[254773,880,0.01,0.09,3.16992500144231,0.641417538461538,"*",0.499032,"LYG2","NA","NA","NA","K01446//peptidoglycan recognition protein","XP_008006348.1//PREDICTED: lysozyme g-like protein 2 isoform X3 [Chlorocebus sabaeus]","3//A2MP1"]
[390883,939,0.01,0.09,3.16992500144231,0.640027070895223,"*",0.499032,"OR7G3","NA","NA","NA","K04257//olfactory receptor","XP_004059995.2//PREDICTED: olfactory receptor 7G3 [Gorilla gorilla gorilla]","1//3"]
[54855,5720,0.03,0.26,3.11547721741994,0.000455309887233533,"Up",0.0001190008,"FAM46C","NA","NA","NA","K05742//solute carrier family 9 (sodium/hydrogen exchanger), member 1","XP_011945349.1//PREDICTED: protein FAM46C isoform X1 [Cercocebus atys]","3//A2MP1"]
[3433,3505,0.16,1.38,3.10852445677817,{"v":4.05235267579909e-11,"d":"4.05E-11"},"Up",{"v":3.88898e-12,"d":"3.89E-12"},"IFIT2","GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0003723//RNA binding","GO:0060337//type I interferon signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0032091//negative regulation of protein binding;GO:0051607//defense response to virus;GO:0008637//apoptotic mitochondrial changes;GO:0009615//response to virus;GO:0035457//cellular response to interferon-alpha","K14217//interferon-induced protein with tetratricopeptide repeats 1","AAH32839.2//Interferon-induced protein with tetratricopeptide repeats 2 [Homo sapiens]",4]
[441108,805,0.41,3.52,3.10187961401921,{"v":1.88216649040203e-06,"d":"1.88E-06"},"Up",{"v":3.2532E-7,"d":"3.25E-07"},"C5orf56","NA","NA","NA","NA","XP_005557781.1//PREDICTED: uncharacterized protein LOC102122672 isoform X2 [Macaca fascicularis]","2//1"]
[27063,1994,0.89,7.49,3.07308847749235,{"v":2.95588382020202e-32,"d":"2.96E-32"},"Up",{"v":7.32772e-34,"d":"7.33E-34"},"ANKRD1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription factor complex;GO:0005829//cytosol;GO:0031674//I band;GO:0001650//fibrillar center;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0001105//RNA polymerase II transcription coactivator activity;GO:0002039//p53 binding;GO:0042826//histone deacetylase binding;GO:0061629//RNA polymerase II sequence-specific DNA binding transcription factor binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0070412//R-SMAD binding;GO:0031432//titin binding","GO:0071456//cellular response to hypoxia;GO:0071260//cellular response to mechanical stimulus;GO:0035690//cellular response to drug;GO:0071222//cellular response to lipopolysaccharide;GO:0071356//cellular response to tumor necrosis factor;GO:0055008//cardiac muscle tissue morphogenesis;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0043065//positive regulation of apoptotic process;GO:0045445//myoblast differentiation;GO:0071347//cellular response to interleukin-1;GO:0071407//cellular response to organic cyclic compound;GO:0019216//regulation of lipid metabolic process;GO:0043517//positive regulation of DNA damage response, signal transduction by p53 class mediator;GO:0035994//response to muscle stretch;GO:0045214//sarcomere organization;GO:0010976//positive regulation of neuron projection development;GO:2000279//negative regulation of DNA biosynthetic process;GO:0050714//positive regulation of protein secretion;GO:0035914//skeletal muscle cell differentiation","K21433//ankyrin repeat domain-containing protein 1","NP_055206.2//ankyrin repeat domain-containing protein 1 [Homo sapiens]","2//1"]
[3426,2196,0.04,0.33,3.04439411935845,0.0294976036375199,"*",0.01161512,"CFI","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005576//extracellular region","GO:0004252//serine-type endopeptidase activity;GO:0046872//metal ion binding;GO:0005044//scavenger receptor activity","GO:0006958//complement activation, classical pathway;GO:0030449//regulation of complement activation;GO:0045087//innate immune response","K01333//complement factor I [EC:3.4.21.45]","NP_000195.2//complement factor I isoform 2 preproprotein [Homo sapiens];NP_001317964.1//complement factor I isoform 3 preproprotein [Homo sapiens];NP_001304986.1//complement factor I isoform 1 preproprotein [Homo sapiens]","1//3;4"]
[388436,1915,0.31,2.54,3.03448837638529,{"v":7.10884583111111e-11,"d":"7.11E-11"},"Up",{"v":7.00916E-12,"d":"7.01E-12"},"LOC388436","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein;K12581//CCR4-NOT transcription complex subunit 7/8","NP_001278833.2//uncharacterized protein ENSP00000382033 [Homo sapiens]","2//1"]
[100141515,1090,0.01,0.08,3,0.655985612903226,"*",0.499032,"C17orf99","GO:0005576//extracellular region","NA","NA","K21988//transmembrane channel-like protein","NP_001156547.1//uncharacterized protein C17orf99 precursor [Homo sapiens]","1//3"]
[3761,1913,0.01,0.08,3,0.395618765623448,"*",0.249274,"KCNJ4","GO:0016323//basolateral plasma membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0045211//postsynaptic membrane;GO:0030659//cytoplasmic vesicle membrane","GO:0005242//inward rectifier potassium channel activity;GO:0015467//G-protein activated inward rectifier potassium channel activity;GO:0030165//PDZ domain binding","GO:0006813//potassium ion transport;GO:0061337//cardiac conduction;GO:0010107//potassium ion import","K04998//potassium inwardly-rectifying channel subfamily J member 4","NP_004972.1//inward rectifier potassium channel 4 [Homo sapiens]","1//3;2//1"]
[3823,1042,0.01,0.08,3,0.654692605781866,"*",0.499032,"KLRC3","GO:0016021//integral component of membrane","GO:0030246//carbohydrate binding;GO:0004888//transmembrane signaling receptor activity","GO:0006968//cellular defense response","K06541//killer cell lectin-like receptor subfamily C","NP_031359.2//NKG2-E type II integral membrane protein isoform H [Homo sapiens];NP_002252.2//NKG2-E type II integral membrane protein isoform E [Homo sapiens]","2//1"]
[400757,2177,0.01,0.08,3,0.395461602542457,"*",0.249274,"C1orf141","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein;K04948//cyclic nucleotide gated channel alpha 1","NP_001263281.1//uncharacterized protein C1orf141 isoform 2 [Homo sapiens];NP_001263280.1//uncharacterized protein C1orf141 isoform 1 [Homo sapiens]","1//3"]
[64108,1027,0.01,0.08,3,0.652015145427777,"*",0.499032,"RTP4","GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0005737//cytoplasm","GO:0031849//olfactory receptor binding","GO:0006612//protein targeting to membrane;GO:0051607//defense response to virus;GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0051205//protein insertion into membrane","NA","NP_071430.2//receptor-transporting protein 4 [Homo sapiens]","2//1"]
[339834,2696,0.01,0.08,3,0.226824970737826,"*",0.1245166,"CCDC36","GO:0000794//condensed nuclear chromosome","NA","GO:0007129//synapsis;GO:0042138//meiotic DNA double-strand break formation;GO:0060629//regulation of homologous chromosome segregation;GO:0048477//oogenesis;GO:0007283//spermatogenesis;GO:0006310//DNA recombination","NA","NP_835467.2//interactor of HORMAD1 protein 1 [Homo sapiens]","1//3;3//A2MP1"]
[171169,978,0.01,0.08,3,0.649835914893617,"*",0.499032,"SPACA4","GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0001669//acrosomal vesicle;GO:0005886//plasma membrane;GO:0031225//anchored component of membrane","GO:0003796//lysozyme activity","GO:0007155//cell adhesion;GO:0006501//C-terminal protein lipidation;GO:0050829//defense response to Gram-negative bacterium;GO:0016998//cell wall macromolecule catabolic process;GO:0050830//defense response to Gram-positive bacterium","K19894//sperm acrosome membrane-associated protein 4","NP_598005.1//sperm acrosome membrane-associated protein 4 precursor [Homo sapiens]","2//1"]
[387778,991,0.01,0.08,3,0.649147977850163,"*",0.499032,"SPDYC","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0019901//protein kinase binding","GO:0007049//cell cycle","K08694//speedy","XP_003828661.2//PREDICTED: speedy protein C [Pan paniscus]","2//1"]
[400668,1075,0.01,0.08,3,0.648989429943825,"*",0.499032,"PRSS57","GO:0005615//extracellular space;GO:0035578//azurophil granule lumen","GO:0004252//serine-type endopeptidase activity;GO:0008201//heparin binding;GO:0008236//serine-type peptidase activity","GO:0006508//proteolysis","K01334//component factor D [EC:3.4.21.46]","NP_001295138.1//serine protease 57 isoform 2 precursor [Homo sapiens];NP_999875.1//serine protease 57 isoform 1 precursor [Homo sapiens]","1//3;4"]
[84970,2136,0.01,0.08,3,0.393702083844176,"*",0.249274,"C1orf94","NA","NA","NA","K17495//CUB and sushi domain-containing protein","NP_001128206.1//uncharacterized protein C1orf94 isoform a [Homo sapiens];XP_004025462.2//PREDICTED: uncharacterized protein C1orf94 homolog [Gorilla gorilla gorilla]","4;1//3"]
[285852,2088,0.01,0.08,3,0.393507547781401,"*",0.249274,"TREML4","GO:0005576//extracellular region;GO:0005886//plasma membrane","NA","GO:0034157//positive regulation of toll-like receptor 7 signaling pathway;GO:0045087//innate immune response;GO:0050776//regulation of immune response","K06742//natural cytotoxicity triggering receptor 2;K14364//trem-like transcript 2 protein","NP_937796.1//trem-like transcript 4 protein precursor [Homo sapiens]","2//1"]
[259289,1027,0.01,0.08,3,0.64562542868713,"*",0.499032,"TAS2R43","GO:0060170//ciliary membrane;GO:0031514//motile cilium;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0008527//taste receptor activity;GO:0033038//bitter taste receptor activity;GO:0004930//G-protein coupled receptor activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste","K08474//taste receptor type 2","NP_795365.2//taste receptor type 2 member 43 [Homo sapiens]","2//1"]
[440087,2104,0.01,0.08,3,0.392615152435417,"*",0.249274,"SMCO3","GO:0016021//integral component of membrane","NA","NA","NA","XP_011913868.1//PREDICTED: single-pass membrane and coiled-coil domain-containing protein 3 isoform X1 [Cercocebus atys]","2//1"]
[256223,1051,0.01,0.08,3,0.64167569572567,"*",0.499032,"CDRT15L2","GO:0016021//integral component of membrane","NA","NA","NA","NP_001177719.1//CMT1A duplicated region transcript 15 protein-like protein [Homo sapiens]","1//3"]
[1581,2875,0.01,0.08,3,0.226051615910899,"*",0.1245166,"CYP7A1","GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0020037//heme binding;GO:0008123//cholesterol 7-alpha-monooxygenase activity;GO:0005506//iron ion binding","GO:0071333//cellular response to glucose stimulus;GO:0071397//cellular response to cholesterol;GO:0006707//cholesterol catabolic process;GO:0019216//regulation of lipid metabolic process;GO:0070857//regulation of bile acid biosynthetic process;GO:0042632//cholesterol homeostasis;GO:0016125//sterol metabolic process;GO:0006699//bile acid biosynthetic process","K00489//cholesterol 7alpha-monooxygenase [EC:1.14.14.23]","NP_000771.2//cholesterol 7-alpha-monooxygenase [Homo sapiens]","3//A2MP1"]
[3753,3151,0.01,0.08,3,0.226025928227273,"*",0.1245166,"KCNE1","NA","NA","NA","K04894//potassium voltage-gated channel Isk-related subfamily E member 1","XP_011724448.1//PREDICTED: potassium voltage-gated channel subfamily E member 1 isoform X1 [Macaca nemestrina];XP_016883831.1//PREDICTED: potassium voltage-gated channel subfamily E member 1 isoform X1 [Homo sapiens]","3//A2MP1;2//1;5"]
[2636,1092,0.01,0.08,3,0.639308458416874,"*",0.499032,"GBX1","GO:0005634//nucleus","GO:0043565//sequence-specific DNA binding","GO:0097374//sensory neuron axon guidance;GO:0006355//regulation of transcription, DNA-templated;GO:0007628//adult walking behavior;GO:0021522//spinal cord motor neuron differentiation;GO:0019230//proprioception;GO:0048663//neuron fate commitment;GO:0006351//transcription, DNA-templated","K09321//homeobox protein GBX","NP_001092304.1//homeobox protein GBX-1 [Homo sapiens]","2//1"]
[7134,705,0.12,0.95,2.98489310760979,0.0503225857522909,"*",0.0213148,"TNNC1","GO:0005829//cytosol;GO:0043292//contractile fiber;GO:0005861//troponin complex;GO:1990584//cardiac Troponin complex","GO:0051015//actin filament binding;GO:0005509//calcium ion binding;GO:0048306//calcium-dependent protein binding;GO:0042803//protein homodimerization activity;GO:0031014//troponin T binding;GO:0031013//troponin I binding","GO:0032972//regulation of muscle filament sliding speed;GO:0030049//muscle filament sliding;GO:0014883//transition between fast and slow fiber;GO:0002086//diaphragm contraction;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0043462//regulation of ATPase activity;GO:0006937//regulation of muscle contraction;GO:0060048//cardiac muscle contraction;GO:0010038//response to metal ion;GO:0003009//skeletal muscle contraction","K05865//troponin C, slow skeletal and cardiac muscles","EDL24796.1//troponin C, cardiac/slow skeletal, partial [Mus musculus]","2//1"]
[1475,838,0.1,0.79,2.98185265328974,0.0503151492832865,"*",0.0213148,"CSTA","GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0001533//cornified envelope;GO:0005737//cytoplasm","GO:0002020//protease binding;GO:0030674//protein binding, bridging;GO:0005198//structural molecule activity;GO:0004869//cysteine-type endopeptidase inhibitor activity","GO:0018149//peptide cross-linking;GO:0098609//cell-cell adhesion;GO:0010466//negative regulation of peptidase activity;GO:0045861//negative regulation of proteolysis;GO:0030216//keratinocyte differentiation;GO:0070268//cornification","K13907//cystatin-A/B","XP_008706392.1//PREDICTED: cystatin-A isoform X1 [Ursus maritimus]","3//A2MP1"]
[6347,760,100.35,791.62,2.97976744532654,0,"Up",0,"CCL2","GO:0030425//dendrite;GO:0044299//C-fiber;GO:0005615//extracellular space;GO:0030139//endocytic vesicle;GO:0005622//intracellular;GO:0043679//axon terminus","GO:0004672//protein kinase activity;GO:0008201//heparin binding;GO:0031727//CCR2 chemokine receptor binding;GO:0048020//CCR chemokine receptor binding;GO:0008009//chemokine activity","GO:0031100//animal organ regeneration;GO:0043491//protein kinase B signaling;GO:0071356//cellular response to tumor necrosis factor;GO:0071346//cellular response to interferon-gamma;GO:0071347//cellular response to interleukin-1;GO:2000427//positive regulation of apoptotic cell clearance;GO:0010574//regulation of vascular endothelial growth factor production;GO:2000502//negative regulation of natural killer cell chemotaxis;GO:0048246//macrophage chemotaxis;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0009611//response to wounding;GO:0048247//lymphocyte chemotaxis;GO:0035684//helper T cell extravasation;GO:0001525//angiogenesis;GO:0090026//positive regulation of monocyte chemotaxis;GO:0043524//negative regulation of neuron apoptotic process;GO:0070098//chemokine-mediated signaling pathway;GO:0008360//regulation of cell shape;GO:0043615//astrocyte cell migration;GO:0007010//cytoskeleton organization;GO:0019221//cytokine-mediated signaling pathway;GO:0010759//positive regulation of macrophage chemotaxis;GO:0043547//positive regulation of GTPase activity;GO:0090280//positive regulation of calcium ion import;GO:0051770//positive regulation of nitric-oxide synthase biosynthetic process;GO:0071407//cellular response to organic cyclic compound;GO:0002548//monocyte chemotaxis;GO:0090265//positive regulation of immune complex clearance by monocytes and macrophages;GO:0007186//G-protein coupled receptor signaling pathway;GO:0000165//MAPK cascade;GO:0030593//neutrophil chemotaxis;GO:0016525//negative regulation of angiogenesis;GO:0050870//positive regulation of T cell activation;GO:0034351//negative regulation of glial cell apoptotic process;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0006954//inflammatory response;GO:0007568//aging;GO:0009887//animal organ morphogenesis;GO:0006955//immune response;GO:0070374//positive regulation of ERK1 and ERK2 cascade","K14624//C-C motif chemokine 2","XP_008009200.1//PREDICTED: C-C motif chemokine 2 [Chlorocebus sabaeus]","3//A2MP1"]
[100527963,794,0.8,6.29,2.97498811199193,{"v":1.25294175024876e-10,"d":"1.25E-10"},"Up",{"v":1.261256E-11,"d":"1.26E-11"},"PMF1-BGLAP","GO:0043231//intracellular membrane-bounded organelle;GO:0005654//nucleoplasm;GO:0005667//transcription factor complex;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0000777//condensed chromosome kinetochore;GO:0000444//MIS12/MIND type complex","GO:0003713//transcription coactivator activity;GO:0043522//leucine zipper domain binding","GO:0007059//chromosome segregation;GO:0007062//sister chromatid cohesion;GO:0006355//regulation of transcription, DNA-templated;GO:0051301//cell division;GO:0006366//transcription from RNA polymerase II promoter","K11546//polyamine-modulated factor 1","NP_001186592.1//PMF1-BGLAP protein isoform 3 [Homo sapiens];NP_001186591.1//PMF1-BGLAP protein isoform 2 [Homo sapiens];NP_001186593.1//PMF1-BGLAP protein isoform 4 [Homo sapiens];NP_001186590.1//PMF1-BGLAP protein isoform 1 [Homo sapiens]","1//3"]
[389898,1185,0.12,0.94,2.96962635095648,0.00311601906291726,"*",0.000964222,"UBE2NL","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0061630//ubiquitin protein ligase activity;GO:0031625//ubiquitin protein ligase binding","GO:0070534//protein K63-linked ubiquitination;GO:0006301//postreplication repair","K10580//ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]","NP_001013007.1//putative ubiquitin-conjugating enzyme E2 N-like [Homo sapiens]","2//1"]
[810,1417,0.11,0.86,2.9668331360648,0.00408352609441043,"*",0.001294284,"CALML3","GO:0070062//extracellular exosome","GO:0005509//calcium ion binding","NA","K02183//calmodulin","NP_005176.1//calmodulin-like protein 3 [Homo sapiens]","3//A2MP1"]
[84166,6742,0.99,7.7,2.95935801550265,{"v":4.4593703e-109,"d":"4.46E-109"},"Up",{"v":2.34498e-111,"d":"2.34E-111"},"NLRC5","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005813//centrosome;GO:0005737//cytoplasm","GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0005524//ATP binding","GO:0051607//defense response to virus;GO:0045345//positive regulation of MHC class I biosynthetic process;GO:0060335//positive regulation of interferon-gamma-mediated signaling pathway;GO:0060340//positive regulation of type I interferon-mediated signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0032480//negative regulation of type I interferon production;GO:0045087//innate immune response;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0060339//negative regulation of type I interferon-mediated signaling pathway;GO:0043549//regulation of kinase activity","K08060//class II, major histocompatibility complex, transactivator","NP_115582.4//protein NLRC5 isoform 1 [Homo sapiens];NP_001317481.1//protein NLRC5 isoform 2 [Homo sapiens]","4;1//3"]
[110384692,5427,0.04,0.31,2.95419631038687,1.47528484934383E-4,"Up",{"v":3.51874e-05,"d":"3.52E-05"},"LOC110384692","NA","NA","NA","K03989//complement component 4","NP_001338929.1//complement C4A (Rodgers blood group)-like preproprotein [Homo sapiens]","1//3"]
[56165,4510,0.02,0.15,2.90689059560852,0.0503077150118203,"*",0.0213148,"TDRD1","GO:0071546//pi-body;GO:0033391//chromatoid body;GO:0043186//P granule;GO:0005737//cytoplasm","GO:0046872//metal ion binding","GO:0007281//germ cell development;GO:0007275//multicellular organism development;GO:0051321//meiotic cell cycle;GO:0043046//DNA methylation involved in gamete generation;GO:0031047//gene silencing by RNA;GO:0007283//spermatogenesis;GO:0034587//piRNA metabolic process","K18405//tudor domain-containing protein 1/4/6/7","NP_942090.1//tudor domain-containing protein 1 [Homo sapiens]","1//3"]
[9235,917,6.97,49.21,2.81972095526172,{"v":2.89351895e-88,"d":"2.89E-88"},"Up",{"v":2.02876e-90,"d":"2.03E-90"},"IL32","GO:0016020//membrane;GO:0005615//extracellular space;GO:0005829//cytosol","GO:0005125//cytokine activity","GO:0007155//cell adhesion;GO:0006952//defense response;GO:0006955//immune response","NA","NP_001012649.1//interleukin-32 isoform B [Homo sapiens];NP_001295007.1//interleukin-32 isoform E precursor [Homo sapiens];XP_016784733.1//PREDICTED: interleukin-32 isoform X3 [Pan troglodytes];NP_001012652.1//interleukin-32 isoform C [Homo sapiens];NP_001012654.1//interleukin-32 isoform D [Homo sapiens]","4;1//3"]
[3123,1280,0.01,0.07,2.8073549220576,0.654907752875452,"*",0.499032,"HLA-DRB1","NA","NA","NA","K06752//major histocompatibility complex, class II","AAU87993.1//MHC class II antigen [Homo sapiens];Q9TQE0.1//RecName: Full=HLA class II histocompatibility antigen, DRB1-9 beta chain; AltName: Full=MHC class II antigen DRB1*9; Short=DR-9; Short=DR9; Flags: Precursor;AAB63307.1//MHC class II DRB [Macaca mulatta];CDR98297.1//MHC class II antigen [Homo sapiens]","1//3;3//A2MP1"]
[6540,2226,0.01,0.07,2.8073549220576,0.395540168471243,"*",0.249274,"SLC6A13","GO:0070062//extracellular exosome;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane","GO:0005332//gamma-aminobutyric acid:sodium symporter activity;GO:0005328//neurotransmitter:sodium symporter activity;GO:0005215//transporter activity","GO:0006810//transport","K05039//solute carrier family 6 (neurotransmitter transporter, GABA) member 6/8/11/12/13","XP_016778176.1//PREDICTED: sodium- and chloride-dependent GABA transporter 2 isoform X1 [Pan troglodytes];XP_011822522.1//PREDICTED: sodium- and chloride-dependent GABA transporter 2 [Mandrillus leucophaeus];NP_001230321.1//sodium- and chloride-dependent GABA transporter 2 isoform 3 [Homo sapiens]","1//3;4;2//1"]
[353132,1197,0.01,0.07,2.8073549220576,0.654370150057462,"*",0.499032,"LCE1B","GO:0001533//cornified envelope;GO:0005737//cytoplasm","GO:0005198//structural molecule activity","GO:0018149//peptide cross-linking;GO:0030216//keratinocyte differentiation;GO:0031424//keratinization","K10385//loricrin","NP_848126.1//late cornified envelope protein 1B [Homo sapiens]","1//3"]
[3593,2347,0.01,0.07,2.8073549220576,0.395500881605085,"*",0.249274,"IL12B","GO:0016020//membrane;GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0043514//interleukin-12 complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005576//extracellular region;GO:0070743//interleukin-23 complex","GO:0008083//growth factor activity;GO:0045519//interleukin-23 receptor binding;GO:0005125//cytokine activity;GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity;GO:0004896//cytokine receptor activity;GO:0042803//protein homodimerization activity;GO:0042164//interleukin-12 alpha subunit binding","GO:0016477//cell migration;GO:0071222//cellular response to lipopolysaccharide;GO:0032740//positive regulation of interleukin-17 production;GO:0045672//positive regulation of osteoclast differentiation;GO:0071346//cellular response to interferon-gamma;GO:0032760//positive regulation of tumor necrosis factor production;GO:0035744//T-helper 1 cell cytokine production;GO:0002827//positive regulation of T-helper 1 type immune response;GO:0032729//positive regulation of interferon-gamma production;GO:0042104//positive regulation of activated T cell proliferation;GO:0002860//positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target;GO:0010536//positive regulation of activation of Janus kinase activity;GO:0034393//positive regulation of smooth muscle cell apoptotic process;GO:0032609//interferon-gamma production;GO:0042093//T-helper cell differentiation;GO:0032725//positive regulation of granulocyte macrophage colony-stimulating factor production;GO:0030101//natural killer cell activation;GO:0044130//negative regulation of growth of symbiont in host;GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0032733//positive regulation of interleukin-10 production;GO:0050829//defense response to Gram-negative bacterium;GO:0032693//negative regulation of interleukin-10 production;GO:0032819//positive regulation of natural killer cell proliferation;GO:0007050//cell cycle arrest;GO:0008283//cell proliferation;GO:0032735//positive regulation of interleukin-12 production;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0042832//defense response to protozoan;GO:0051607//defense response to virus;GO:0010224//response to UV-B;GO:0051142//positive regulation of NK T cell proliferation;GO:0002862//negative regulation of inflammatory response to antigenic stimulus;GO:0032700//negative regulation of interleukin-17 production;GO:0002230//positive regulation of defense response to virus by host","K05425//interleukin 12B","NP_002178.2//interleukin-12 subunit beta precursor [Homo sapiens]","2//1"]
[8838,1252,0.01,0.07,2.8073549220576,0.653083497296412,"*",0.499032,"WISP3","GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix","GO:0005520//insulin-like growth factor binding;GO:0008083//growth factor activity;GO:0005178//integrin binding;GO:0008201//heparin binding","GO:0001558//regulation of cell growth;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0060548//negative regulation of cell death","K06827//connective tissue growth factor","XP_012293878.2//WNT1-inducible-signaling pathway protein 3 [Aotus nancymaae];NP_937882.1//WNT1-inducible-signaling pathway protein 3 isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[283129,1121,0.01,0.07,2.8073549220576,0.652709176123803,"*",0.499032,"MAJIN","GO:0000784//nuclear chromosome, telomeric region;GO:0005639//integral component of nuclear inner membrane","GO:0003677//DNA binding","GO:0007129//synapsis;GO:0045141//meiotic telomere clustering;GO:0070197//meiotic attachment of telomere to nuclear envelope","NA","NP_001032302.1//membrane-anchored junction protein isoform 1 [Homo sapiens];XP_005273975.1//PREDICTED: membrane-anchored junction protein isoform X3 [Homo sapiens];NP_001287732.1//membrane-anchored junction protein isoform 2 [Homo sapiens]","1//3;2//1"]
[284359,1505,0.01,0.07,2.8073549220576,0.652335283797054,"*",0.499032,"IZUMO1","GO:0016021//integral component of membrane;GO:0002080//acrosomal membrane;GO:0005886//plasma membrane","GO:0086080//protein binding involved in heterotypic cell-cell adhesion;GO:0042802//identical protein binding;GO:0005102//receptor binding;GO:0042803//protein homodimerization activity","GO:0007155//cell adhesion;GO:0035036//sperm-egg recognition;GO:0007338//single fertilization;GO:0034113//heterotypic cell-cell adhesion;GO:0007342//fusion of sperm to egg plasma membrane involved in single fertilization","NA","EAW52397.1//izumo sperm-egg fusion 1, isoform CRA_c [Homo sapiens];XP_016882135.1//PREDICTED: izumo sperm-egg fusion protein 1 isoform X1 [Homo sapiens]","1//3;2//1"]
[9389,2176,0.01,0.07,2.8073549220576,0.394834196926128,"*",0.249274,"SLC22A14","GO:0005887//integral component of plasma membrane","GO:0015101//organic cation transmembrane transporter activity;GO:0005452//inorganic anion exchanger activity;GO:0015347//sodium-independent organic anion transmembrane transporter activity","GO:0043252//sodium-independent organic anion transport;GO:0015695//organic cation transport","K08210//MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 14","XP_006713479.2//PREDICTED: solute carrier family 22 member 14 isoform X1 [Homo sapiens]","1//3;4"]
[27240,1238,0.01,0.07,2.8073549220576,0.651535526604005,"*",0.499032,"SIT1","GO:0070062//extracellular exosome;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0019900//kinase binding;GO:0042169//SH2 domain binding","GO:0050863//regulation of T cell activation;GO:0043029//T cell homeostasis;GO:0007165//signal transduction;GO:0002250//adaptive immune response","NA","NP_055265.1//signaling threshold-regulating transmembrane adapter 1 precursor [Homo sapiens]","2//1"]
[1029,1164,0.01,0.07,2.8073549220576,0.650843988242978,"*",0.499032,"CDKN2A","GO:0005654//nucleoplasm;GO:0001652//granular component;GO:0005634//nucleus;GO:0035985//senescence-associated heterochromatin focus;GO:0043234//protein complex;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0055105//ubiquitin-protein transferase inhibitor activity;GO:0047485//protein N-terminus binding;GO:0016301//kinase activity;GO:0019901//protein kinase binding;GO:0004861//cyclin-dependent protein serine/threonine kinase inhibitor activity;GO:0051059//NF-kappaB binding;GO:0003700//DNA binding transcription factor activity;GO:0097371//MDM2/MDM4 family protein binding","GO:0051444//negative regulation of ubiquitin-protein transferase activity;GO:0048103//somatic stem cell division;GO:0035019//somatic stem cell population maintenance;GO:0042593//glucose homeostasis;GO:0032091//negative regulation of protein binding;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0070301//cellular response to hydrogen peroxide;GO:0008285//negative regulation of cell proliferation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0035986//senescence-associated heterochromatin focus assembly;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0090399//replicative senescence;GO:0042326//negative regulation of phosphorylation;GO:0034393//positive regulation of smooth muscle cell apoptotic process;GO:0006915//apoptotic process;GO:0008544//epidermis development;GO:2000059//negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0030889//negative regulation of B cell proliferation;GO:0001953//negative regulation of cell-matrix adhesion;GO:0000082//G1/S transition of mitotic cell cycle;GO:0009303//rRNA transcription;GO:0060058//positive regulation of apoptotic process involved in mammary gland involution;GO:0007050//cell cycle arrest;GO:0045893//positive regulation of transcription, DNA-templated;GO:0033088//negative regulation of immature T cell proliferation in thymus;GO:0090398//cellular senescence;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0030308//negative regulation of cell growth;GO:2000111//positive regulation of macrophage apoptotic process;GO:0046822//regulation of nucleocytoplasmic transport;GO:2000774//positive regulation of cellular senescence;GO:0031647//regulation of protein stability;GO:0007265//Ras protein signal transduction;GO:0033600//negative regulation of mammary gland epithelial cell proliferation","K06621//cyclin-dependent kinase inhibitor 2A","NP_000068.1//cyclin-dependent kinase inhibitor 2A isoform p16INK4a [Homo sapiens];NP_478104.2//cyclin-dependent kinase inhibitor 2A isoform p12 [Homo sapiens];NP_001182061.1//cyclin-dependent kinase inhibitor 2A isoform p16gamma [Homo sapiens];AAC60649.1//tumor supressor, partial [Homo sapiens]","4;1//3;3//A2MP1"]
[388646,2454,0.01,0.07,2.8073549220576,0.3943649476082,"*",0.249274,"GBP7","NA","NA","NA","K20899//guanylate-binding protein 1/3/4/7","XP_011741466.1//PREDICTED: guanylate-binding protein 7 [Macaca nemestrina]","2//1"]
[26584,1227,0.01,0.07,2.8073549220576,0.649359495601173,"*",0.499032,"DUX1","NA","NA","NA","K18490//homeobox protein OTX2;K09381//paired box protein 3/7;K09332//retina and anterior neural fold homeobox protein","BAA07227.1//facioscapulohumeral muscular dystrophy [Homo sapiens]","1//3"]
[83888,1188,0.01,0.07,2.8073549220576,0.649306603241834,"*",0.499032,"FGFBP2","GO:0005615//extracellular space","GO:0019838//growth factor binding","NA","NA","NP_114156.1//fibroblast growth factor-binding protein 2 precursor [Homo sapiens]","3//A2MP1"]
[1036,1220,0.01,0.07,2.8073549220576,0.649095119941373,"*",0.499032,"CDO1","GO:0005829//cytosol","GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0005506//iron ion binding;GO:0017172//cysteine dioxygenase activity;GO:0008198//ferrous iron binding","GO:0007595//lactation;GO:0042412//taurine biosynthetic process;GO:0043200//response to amino acid;GO:0000097//sulfur amino acid biosynthetic process;GO:0051591//response to cAMP;GO:0055114//oxidation-reduction process;GO:0045471//response to ethanol;GO:0006954//inflammatory response;GO:0006534//cysteine metabolic process;GO:0033762//response to glucagon;GO:0019448//L-cysteine catabolic process;GO:0051384//response to glucocorticoid","K00456//cysteine dioxygenase [EC:1.13.11.20]","NP_001792.2//cysteine dioxygenase type 1 isoform 2 [Homo sapiens];NP_001310494.1//cysteine dioxygenase type 1 isoform 1 [Homo sapiens];NP_001310495.1//cysteine dioxygenase type 1 isoform 3 [Homo sapiens]","1//3;2//1"]
[195814,3403,0.01,0.07,2.8073549220576,0.226566598519194,"*",0.1245166,"SDR16C5","GO:0017053//transcriptional repressor complex;GO:0005634//nucleus;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0004745//retinol dehydrogenase activity;GO:0001191//transcriptional repressor activity, RNA polymerase II transcription factor binding;GO:0008134//transcription factor binding;GO:0033613//activating transcription factor binding","GO:0031065//positive regulation of histone deacetylation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0043616//keratinocyte proliferation;GO:0042572//retinol metabolic process;GO:0042574//retinal metabolic process;GO:0035067//negative regulation of histone acetylation","K15734//all-trans-retinol dehydrogenase (NAD+) [EC:1.1.1.105]","NP_620419.2//epidermal retinol dehydrogenase 2 isoform 2 [Homo sapiens];NP_001304978.1//epidermal retinol dehydrogenase 2 isoform 1 [Homo sapiens];NP_001304979.1//epidermal retinol dehydrogenase 2 isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[4063,2280,0.01,0.07,2.8073549220576,0.393313203871987,"*",0.249274,"LY9","GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","NA","GO:0072540//T-helper 17 cell lineage commitment;GO:0007155//cell adhesion;GO:0032740//positive regulation of interleukin-17 production;GO:0045087//innate immune response","K06570//lymphocyte antigen 9","XP_007974657.1//PREDICTED: LOW QUALITY PROTEIN: T-lymphocyte surface antigen Ly-9-like [Chlorocebus sabaeus];NP_001248385.1//T-lymphocyte surface antigen Ly-9 isoform c [Homo sapiens];NP_002339.2//T-lymphocyte surface antigen Ly-9 isoform a precursor [Homo sapiens];NP_001248386.1//T-lymphocyte surface antigen Ly-9 isoform d precursor [Homo sapiens]","1//3;3//A2MP1;2//1"]
[5104,2352,0.01,0.07,2.8073549220576,0.393235520047403,"*",0.249274,"SERPINA5","GO:0036029//protein C inhibitor-KLK3 complex;GO:0016020//membrane;GO:0097181//protein C inhibitor-coagulation factor V complex;GO:0005615//extracellular space;GO:0097183//protein C inhibitor-coagulation factor XI complex;GO:0009897//external side of plasma membrane;GO:0097182//protein C inhibitor-coagulation factor Xa complex;GO:0036027//protein C inhibitor-PLAU complex;GO:0005576//extracellular region;GO:0036024//protein C inhibitor-TMPRSS7 complex;GO:0002080//acrosomal membrane;GO:0036025//protein C inhibitor-TMPRSS11E complex;GO:0070062//extracellular exosome;GO:0036026//protein C inhibitor-PLAT complex;GO:0036030//protein C inhibitor-plasma kallikrein complex;GO:0031091//platelet alpha granule;GO:0043234//protein complex;GO:0036028//protein C inhibitor-thrombin complex;GO:0031094//platelet dense tubular network","GO:0002020//protease binding;GO:0032190//acrosin binding;GO:0031210//phosphatidylcholine binding;GO:0008233//peptidase activity;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005539//glycosaminoglycan binding;GO:0008201//heparin binding;GO:0001972//retinoic acid binding","GO:0061107//seminal vesicle development;GO:0007596//blood coagulation;GO:0006869//lipid transport;GO:0007342//fusion of sperm to egg plasma membrane involved in single fertilization;GO:0007283//spermatogenesis;GO:0051346//negative regulation of hydrolase activity","K03913//protein C inhibitor","NP_000615.3//plasma serine protease inhibitor preproprotein [Homo sapiens]",5]
[283385,1172,0.01,0.07,2.8073549220576,0.646358320603259,"*",0.499032,"MORN3","GO:0005634//nucleus","NA","NA","K19755//radial spoke head protein 1;K04575//amyotrophic lateral sclerosis 2 protein","XP_008003191.1//PREDICTED: MORN repeat-containing protein 3 isoform X1 [Chlorocebus sabaeus]",4]
[140700,2196,0.01,0.07,2.8073549220576,0.392925091375567,"*",0.249274,"SAMD10","NA","NA","NA","K03129//transcription initiation factor TFIID subunit 4;K19720//collagen, type III, alpha","XP_019492756.1//PREDICTED: zinc finger protein 512B isoform X9 [Hipposideros armiger]",4]
[401124,3210,0.01,0.07,2.8073549220576,0.226334566272189,"*",0.1245166,"DTHD1","NA","NA","GO:0007165//signal transduction","K10130//leucine-rich repeats and death domain-containing protein","XP_006714077.1//PREDICTED: death domain-containing protein 1 isoform X2 [Homo sapiens];NP_001130008.2//death domain-containing protein 1 isoform 2 [Homo sapiens]","4;2//1"]
[79626,1199,0.01,0.07,2.8073549220576,0.644060529045811,"*",0.499032,"TNFAIP8L2","GO:0005737//cytoplasm","NA","GO:0050868//negative regulation of T cell activation;GO:0042981//regulation of apoptotic process;GO:0050728//negative regulation of inflammatory response;GO:0045087//innate immune response","K12471//epsin","XP_008982578.1//PREDICTED: tumor necrosis factor alpha-induced protein 8-like protein 2 isoform X1 [Callithrix jacchus]",4]
[8433,1157,0.01,0.07,2.8073549220576,0.643748459016393,"*",0.499032,"UTF1","GO:0005634//nucleus","GO:0071837//HMG box domain binding;GO:0003713//transcription coactivator activity","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0008584//male gonad development","K16628//collagen, type VII, alpha","AAT38949.1//ES protein, partial [Homo sapiens]","2//1"]
[149628,2038,0.01,0.07,2.8073549220576,0.643540580285783,"*",0.499032,"PYHIN1","GO:0043234//protein complex;GO:0016607//nuclear speck","GO:0031625//ubiquitin protein ligase binding","GO:1902164//positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator;GO:1900182//positive regulation of protein localization to nucleus;GO:0045893//positive regulation of transcription, DNA-templated;GO:2000060//positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0050821//protein stabilization;GO:0007049//cell cycle;GO:0035457//cellular response to interferon-alpha;GO:0031648//protein destabilization;GO:0043388//positive regulation of DNA binding","K20914//gamma-interferon-inducible protein 16","XP_011834051.1//PREDICTED: pyrin and HIN domain-containing protein 1 isoform X3 [Mandrillus leucophaeus];XP_002810006.1//PREDICTED: pyrin and HIN domain-containing protein 1 isoform X1 [Pongo abelii];XP_525227.5//PREDICTED: pyrin and HIN domain-containing protein 1 isoform X3 [Pan troglodytes];NP_945147.1//pyrin and HIN domain-containing protein 1 isoform beta 1 [Homo sapiens]","4;3//A2MP1"]
[27295,2709,0.01,0.07,2.8073549220576,0.392305702068966,"*",0.249274,"PDLIM3","GO:0030018//Z disc;GO:0005829//cytosol;GO:0015629//actin cytoskeleton","GO:0046872//metal ion binding;GO:0008092//cytoskeletal protein binding;GO:0008307//structural constituent of muscle","GO:0007015//actin filament organization;GO:0007507//heart development","K19867//LIM domain-binding protein 3","NP_001107579.1//PDZ and LIM domain protein 3 isoform b [Homo sapiens];NP_001244891.1//PDZ and LIM domain protein 3 isoform c [Homo sapiens];NP_055291.2//PDZ and LIM domain protein 3 isoform a [Homo sapiens];NP_001244892.1//PDZ and LIM domain protein 3 isoform d [Homo sapiens]","4;1//3;5"]
[653689,1108,0.01,0.07,2.8073549220576,0.643280920593932,"*",0.499032,"GSTT2B","GO:0070062//extracellular exosome;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0004364//glutathione transferase activity;GO:0016740//transferase activity","GO:0006749//glutathione metabolic process;GO:1901687//glutathione derivative biosynthetic process","K00799//glutathione S-transferase [EC:2.5.1.18]","NP_001074312.1//glutathione S-transferase theta-2B [Homo sapiens]","3//A2MP1"]
[153328,2217,0.01,0.07,2.8073549220576,0.641262743785697,"*",0.499032,"SLC25A48","GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion","GO:0022857//transmembrane transporter activity","GO:0055085//transmembrane transport;GO:0006839//mitochondrial transport","K15124//solute carrier family 25, member 48","EAW62206.1//similar to CG4995 gene product, isoform CRA_b, partial [Homo sapiens];NP_001336265.1//solute carrier family 25 member 48 isoform 1 [Homo sapiens];XP_016864580.1//PREDICTED: solute carrier family 25 member 48 isoform X9 [Homo sapiens]","4;1//3"]
[339977,3409,0.01,0.07,2.8073549220576,0.226128714006367,"*",0.1245166,"LRRC66","GO:0016021//integral component of membrane;GO:0005737//cytoplasm","GO:0004860//protein kinase inhibitor activity","GO:0006469//negative regulation of protein kinase activity;GO:0046426//negative regulation of JAK-STAT cascade;GO:0019221//cytokine-mediated signaling pathway","K16358//leucine-rich repeat and fibronectin type-III domain-containing protein 5;K13023//carboxypeptidase N regulatory subunit","NP_001019782.1//leucine-rich repeat-containing protein 66 [Homo sapiens]","2//1"]
[27231,1142,0.01,0.07,2.8073549220576,0.639359734359962,"*",0.499032,"NMRK2","GO:0043231//intracellular membrane-bounded organelle;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0046872//metal ion binding;GO:0061769//ribosylnicotinate kinase activity;GO:0005524//ATP binding;GO:0050262//ribosylnicotinamide kinase activity","GO:0045662//negative regulation of myoblast differentiation;GO:0019674//NAD metabolic process;GO:0009435//NAD biosynthetic process","K10524//nicotinamide/nicotinate riboside kinase [EC:2.7.1.22 2.7.1.173]","NP_001276046.1//nicotinamide riboside kinase 2 isoform 1 [Homo sapiens];NP_733778.1//nicotinamide riboside kinase 2 isoform 2 [Homo sapiens]","1//3;2//1"]
[729665,2610,0.03,0.21,2.8073549220576,0.0851514956712931,"*",0.038791,"CCDC175","NA","NA","NA","K20721//reticulon-1;K20478//golgin subfamily B member 1","NP_001157871.1//coiled-coil domain-containing protein 175 [Homo sapiens]","1//3"]
[23780,2560,10.58,73,2.78655683654072,0,"Up",0,"APOL2","GO:0016021//integral component of membrane;GO:0005576//extracellular region","GO:0008289//lipid binding","GO:0006869//lipid transport;GO:0042157//lipoprotein metabolic process","K14480//apolipoprotein L","BAD92227.1//apolipoprotein L2 variant, partial [Homo sapiens]","3//A2MP1;2//1"]
[51676,2781,0.06,0.4,2.73696559416621,0.00696574494736842,"*",0.00231988,"ASB2","GO:0000151//ubiquitin ligase complex;GO:0005829//cytosol;GO:0031466//Cul5-RING ubiquitin ligase complex","GO:0061630//ubiquitin protein ligase activity","GO:0043687//post-translational protein modification;GO:0007165//signal transduction;GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0045445//myoblast differentiation;GO:0035914//skeletal muscle cell differentiation;GO:0000209//protein polyubiquitination","K10324//ankyrin repeat and SOCS box protein 2","XP_012353411.1//PREDICTED: ankyrin repeat and SOCS box protein 2 isoform X2 [Nomascus leucogenys];NP_001189358.1//ankyrin repeat and SOCS box protein 2 isoform 1 [Homo sapiens]","1//3;4"]
[80231,1927,0.06,0.4,2.73696559416621,0.0295022939863253,"*",0.01161512,"CXorf21","NA","NA","NA","K06689//ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23];K22069//LYR motif-containing protein 4;K12581//CCR4-NOT transcription complex subunit 7/8;K01368//cathepsin S [EC:3.4.22.27]","NP_079435.1//uncharacterized protein CXorf21 [Homo sapiens]","2//1"]
[6737,1946,11.97,77.97,2.70349598224985,{"v":1.13469899529412e-284,"d":"1.13E-284"},"Up",{"v":1.20758E-287,"d":"1.21E-287"},"TRIM21","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031410//cytoplasmic vesicle;GO:0000932//P-body;GO:0005737//cytoplasm;GO:0019005//SCF ubiquitin ligase complex;GO:0005829//cytosol;GO:0030529//intracellular ribonucleoprotein complex;GO:0005776//autophagosome","GO:0003723//RNA binding;GO:0003677//DNA binding;GO:0042802//identical protein binding;GO:0008270//zinc ion binding;GO:0004842//ubiquitin-protein transferase activity","GO:0032479//regulation of type I interferon production;GO:0070206//protein trimerization;GO:0016567//protein ubiquitination;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0034341//response to interferon-gamma;GO:0051865//protein autoubiquitination;GO:0032897//negative regulation of viral transcription;GO:0031648//protein destabilization;GO:0045087//innate immune response;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0000209//protein polyubiquitination;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0090086//negative regulation of protein deubiquitination;GO:0006513//protein monoubiquitination;GO:1902187//negative regulation of viral release from host cell;GO:0010508//positive regulation of autophagy;GO:0046598//positive regulation of viral entry into host cell;GO:0007049//cell cycle;GO:0045787//positive regulation of cell cycle","K10651//tripartite motif-containing protein 21 [EC:2.3.2.27]","NP_003132.2//E3 ubiquitin-protein ligase TRIM21 [Homo sapiens]","3//A2MP1"]
[80830,10156,1.59,10.34,2.70113751503058,{"v":1.8403046375e-201,"d":"1.84E-201"},"Up",{"v":3.6866e-204,"d":"3.69E-204"},"APOL6","GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0008289//lipid binding","GO:0006869//lipid transport;GO:0042157//lipoprotein metabolic process","K14480//apolipoprotein L","NP_085144.1//apolipoprotein L6 [Homo sapiens]","3//A2MP1"]
[3437,2498,2.46,15.6,2.66481580841037,{"v":2.65049469489051e-72,"d":"2.65E-72"},"Up",{"v":2.27318e-74,"d":"2.27E-74"},"IFIT3","GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005737//cytoplasm","GO:0042802//identical protein binding","GO:0060337//type I interferon signaling pathway;GO:0051607//defense response to virus;GO:0043066//negative regulation of apoptotic process;GO:0045087//innate immune response;GO:0009615//response to virus;GO:0035457//cellular response to interferon-alpha;GO:0008285//negative regulation of cell proliferation","K14217//interferon-induced protein with tetratricopeptide repeats 1","NP_001540.2//interferon-induced protein with tetratricopeptide repeats 3 isoform a [Homo sapiens]","1//3;3//A2MP1;5"]
[3852,2320,0.38,2.4,2.65896308216493,{"v":1.11281480873362e-10,"d":"1.11E-10"},"Up",{"v":1.116716e-11,"d":"1.12E-11"},"KRT5","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005882//intermediate filament;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0045095//keratin filament;GO:0005739//mitochondrion;GO:0005886//plasma membrane","GO:0097110//scaffold protein binding;GO:0005198//structural molecule activity;GO:0005200//structural constituent of cytoskeleton","GO:0008544//epidermis development;GO:0031424//keratinization;GO:0031581//hemidesmosome assembly;GO:0070268//cornification","K07605//type II keratin, basic","NP_000415.2//keratin, type II cytoskeletal 5 [Homo sapiens]","3//A2MP1"]
[89870,2241,0.04,0.25,2.64385618977472,0.0851749050171821,"*",0.038791,"TRIM15","GO:0005622//intracellular","GO:0008270//zinc ion binding","GO:0032481//positive regulation of type I interferon production;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:1901253//negative regulation of intracellular transport of viral material;GO:1900246//positive regulation of RIG-I signaling pathway;GO:1902187//negative regulation of viral release from host cell;GO:0007500//mesodermal cell fate determination;GO:0045087//innate immune response","K12005//tripartite motif-containing protein 15","NP_150232.2//tripartite motif-containing protein 15 [Homo sapiens]","2//1"]
[644538,1552,0.05,0.31,2.63226821549951,0.140042607275464,"*",0.0698898,"SMIM10","NA","NA","NA","NA","AAH08642.1//LOC644538 protein, partial [Homo sapiens]","1//3"]
[25818,1398,0.01,0.06,2.58496250072116,0.655554043421053,"*",0.499032,"KLK5","GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005576//extracellular region;GO:0097209//epidermal lamellar body","GO:0004252//serine-type endopeptidase activity;GO:0004175//endopeptidase activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity","GO:0045745//positive regulation of G-protein coupled receptor protein signaling pathway;GO:0008544//epidermis development;GO:0002803//positive regulation of antibacterial peptide production;GO:0070268//cornification","K09617//kallikrein 5 [EC:3.4.21.-]","NP_036559.1//kallikrein-5 preproprotein [Homo sapiens]","1//3;4"]
[2837,1310,0.01,0.06,2.58496250072116,0.655069206015285,"*",0.499032,"UTS2R","GO:0016020//membrane;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0055037//recycling endosome;GO:0005886//plasma membrane;GO:0005769//early endosome","GO:0001604//urotensin II receptor activity;GO:0004930//G-protein coupled receptor activity","GO:0008217//regulation of blood pressure;GO:0010841//positive regulation of circadian sleep/wake cycle, wakefulness;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0045777//positive regulation of blood pressure;GO:0030307//positive regulation of cell growth;GO:0045776//negative regulation of blood pressure;GO:0045907//positive regulation of vasoconstriction;GO:0046005//positive regulation of circadian sleep/wake cycle, REM sleep;GO:0007218//neuropeptide signaling pathway;GO:0045766//positive regulation of angiogenesis;GO:0097746//regulation of blood vessel diameter;GO:0042493//response to drug;GO:0003105//negative regulation of glomerular filtration;GO:0035814//negative regulation of renal sodium excretion;GO:0007165//signal transduction;GO:0048146//positive regulation of fibroblast proliferation;GO:0008015//blood circulation;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0035811//negative regulation of urine volume","K04241//urotensin 2 receptor","NP_061822.1//urotensin-2 receptor [Homo sapiens]","2//1"]
[2532,1258,0.01,0.06,2.58496250072116,0.655015379457683,"*",0.499032,"ACKR1","GO:0016021//integral component of membrane;GO:0055037//recycling endosome;GO:0005886//plasma membrane;GO:0005769//early endosome","GO:0004872//receptor activity;GO:0019956//chemokine binding;GO:0004888//transmembrane signaling receptor activity;GO:0019957//C-C chemokine binding;GO:0004930//G-protein coupled receptor activity","GO:0006952//defense response;GO:0070098//chemokine-mediated signaling pathway;GO:0032642//regulation of chemokine production;GO:0006954//inflammatory response","K06574//Duffy blood group glycoprotein","NP_001116423.1//atypical chemokine receptor 1 isoform a [Homo sapiens];NP_002027.2//atypical chemokine receptor 1 isoform b [Homo sapiens]","3//A2MP1;2//1"]
[680,1413,0.01,0.06,2.58496250072116,0.654262735390676,"*",0.499032,"BRS3","GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0043025//neuronal cell body;GO:0043005//neuron projection","GO:0004946//bombesin receptor activity","GO:0008217//regulation of blood pressure;GO:0006006//glucose metabolic process;GO:0008343//adult feeding behavior","K04170//bombesin-like receptor 3","NP_001718.1//bombesin receptor subtype-3 [Homo sapiens]","1//3"]
[26291,1333,0.01,0.06,2.58496250072116,0.653833429133858,"*",0.499032,"FGF21","GO:0005615//extracellular space;GO:0005623//cell;GO:0005576//extracellular region","GO:0008083//growth factor activity;GO:0005104//fibroblast growth factor receptor binding","GO:0090080//positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway;GO:1901215//negative regulation of neuron death;GO:0010898//positive regulation of triglyceride catabolic process;GO:0071404//cellular response to low-density lipoprotein particle stimulus;GO:0035690//cellular response to drug;GO:0010988//regulation of low-density lipoprotein particle clearance;GO:0046326//positive regulation of glucose import;GO:0045716//positive regulation of low-density lipoprotein particle receptor biosynthetic process;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0030968//endoplasmic reticulum unfolded protein response;GO:1904640//response to methionine;GO:0071377//cellular response to glucagon stimulus;GO:0007165//signal transduction;GO:0014823//response to activity;GO:0007267//cell-cell signaling;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:0071333//cellular response to glucose stimulus;GO:0031667//response to nutrient levels;GO:0072577//endothelial cell apoptotic process;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0008284//positive regulation of cell proliferation","K04358//fibroblast growth factor","NP_061986.1//fibroblast growth factor 21 precursor [Homo sapiens]","3//A2MP1"]
[3595,3782,0.01,0.06,2.58496250072116,0.395186867407701,"*",0.249274,"IL12RB2","GO:0016020//membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004896//cytokine receptor activity;GO:0019901//protein kinase binding","GO:0032496//response to lipopolysaccharide;GO:0007166//cell surface receptor signaling pathway;GO:0032609//interferon-gamma production;GO:0032729//positive regulation of interferon-gamma production;GO:0008284//positive regulation of cell proliferation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0035722//interleukin-12-mediated signaling pathway","K05064//interleukin 12 receptor beta-2","NP_001245144.1//interleukin-12 receptor subunit beta-2 isoform c precursor [Homo sapiens];NP_001245145.1//interleukin-12 receptor subunit beta-2 isoform d precursor [Homo sapiens];NP_001245143.1//interleukin-12 receptor subunit beta-2 isoform b precursor [Homo sapiens];AAI04773.1//Interleukin 12 receptor, beta 2, precursor [Homo sapiens]","1//3;2//1"]
[1959,2855,0.03,0.18,2.58496250072116,0.140060176289048,"*",0.0698898,"EGR2","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm","GO:0071837//HMG box domain binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0031625//ubiquitin protein ligase binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0016874//ligase activity;GO:0046872//metal ion binding;GO:0003682//chromatin binding;GO:0001102//RNA polymerase II activating transcription factor binding;GO:0003700//DNA binding transcription factor activity","GO:0021612//facial nerve structural organization;GO:0016925//protein sumoylation;GO:0021666//rhombomere 5 formation;GO:0007420//brain development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0071310//cellular response to organic substance;GO:0014037//Schwann cell differentiation;GO:0048168//regulation of neuronal synaptic plasticity;GO:0006611//protein export from nucleus;GO:0007611//learning or memory;GO:0007622//rhythmic behavior;GO:0042552//myelination;GO:0008045//motor neuron axon guidance;GO:0032868//response to insulin;GO:0035284//brain segmentation;GO:0021660//rhombomere 3 formation;GO:0006366//transcription from RNA polymerase II promoter;GO:0030278//regulation of ossification;GO:0035914//skeletal muscle cell differentiation;GO:0045444//fat cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007422//peripheral nervous system development","K12496//early growth response protein 2","NP_000390.2//E3 SUMO-protein ligase EGR2 isoform a [Homo sapiens];XP_011537729.1//PREDICTED: E3 SUMO-protein ligase EGR2 isoform X1 [Homo sapiens]","4;1//3;2//1"]
[125972,1295,0.01,0.06,2.58496250072116,0.65335113253012,"*",0.499032,"CALR3","GO:0005788//endoplasmic reticulum lumen;GO:0005783//endoplasmic reticulum","GO:0030246//carbohydrate binding;GO:0051082//unfolded protein binding;GO:0005509//calcium ion binding;GO:0044183//protein binding involved in protein folding","GO:0030154//cell differentiation;GO:0007283//spermatogenesis","K10098//calreticulin 3","NP_659483.2//calreticulin-3 precursor [Homo sapiens]",4]
[7018,3511,0.01,0.06,2.58496250072116,0.395147650689689,"*",0.249274,"TF","GO:0034774//secretory granule lumen;GO:1990712//HFE-transferrin receptor complex;GO:0010008//endosome membrane;GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0005770//late endosome;GO:0016324//apical plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0031232//extrinsic component of external side of plasma membrane;GO:0031982//vesicle;GO:0097433//dense body;GO:0030120//vesicle coat;GO:0005623//cell;GO:0005576//extracellular region;GO:0030665//clathrin-coated vesicle membrane;GO:0055037//recycling endosome;GO:0005769//early endosome;GO:0070062//extracellular exosome;GO:0072562//blood microparticle;GO:0048471//perinuclear region of cytoplasm;GO:0009925//basal plasma membrane;GO:0009986//cell surface;GO:0030139//endocytic vesicle;GO:0005905//clathrin-coated pit;GO:0045178//basal part of cell","GO:0015091//ferric iron transmembrane transporter activity;GO:0008199//ferric iron binding;GO:1990459//transferrin receptor binding;GO:0008198//ferrous iron binding","GO:0043687//post-translational protein modification;GO:0006879//cellular iron ion homeostasis;GO:0001895//retina homeostasis;GO:0098707//ferrous iron import across plasma membrane;GO:0061024//membrane organization;GO:0071281//cellular response to iron ion;GO:0044267//cellular protein metabolic process;GO:0055072//iron ion homeostasis;GO:0002576//platelet degranulation;GO:0031647//regulation of protein stability;GO:0033572//transferrin transport;GO:0048260//positive regulation of receptor-mediated endocytosis","K14736//transferrin","NP_001341632.1//serotransferrin isoform 2 [Homo sapiens];NP_001054.1//serotransferrin isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[196374,2572,0.01,0.06,2.58496250072116,0.395069240599266,"*",0.249274,"KRT78","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0045095//keratin filament","GO:0005198//structural molecule activity","GO:0031424//keratinization;GO:0070268//cornification","K07605//type II keratin, basic","NP_001287743.1//keratin, type II cytoskeletal 78 isoform 2 [Homo sapiens];NP_775487.2//keratin, type II cytoskeletal 78 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[284348,2519,0.01,0.06,2.58496250072116,0.394599432761867,"*",0.249274,"LYPD5","GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0031225//anchored component of membrane","GO:0043236//laminin binding","GO:0007160//cell-matrix adhesion;GO:0006501//C-terminal protein lipidation","K06824//nephronectin","NP_001026919.2//ly6/PLAUR domain-containing protein 5 isoform A precursor [Homo sapiens];XP_016791582.1//PREDICTED: ly6/PLAUR domain-containing protein 5 isoform X1 [Pan troglodytes]","1//3;2//1"]
[6754,1258,0.01,0.06,2.58496250072116,0.651162977291292,"*",0.499032,"SSTR4","GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0043005//neuron projection","GO:0042923//neuropeptide binding;GO:0004994//somatostatin receptor activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0016477//cell migration;GO:0019369//arachidonic acid metabolic process;GO:0030815//negative regulation of cAMP metabolic process;GO:0071385//cellular response to glucocorticoid stimulus;GO:0030900//forebrain development;GO:0043410//positive regulation of MAPK cascade;GO:0007268//chemical synaptic transmission;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0008285//negative regulation of cell proliferation","K04220//somatostatin receptor 4","NP_001043.2//somatostatin receptor type 4 [Homo sapiens]","2//1"]
[29103,2792,0.01,0.06,2.58496250072116,0.394443078355622,"*",0.249274,"DNAJC15","GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane","NA","GO:0009267//cellular response to starvation;GO:0019216//regulation of lipid metabolic process;GO:1902957//negative regulation of mitochondrial electron transport, NADH to ubiquinone;GO:0015031//protein transport;GO:0031333//negative regulation of protein complex assembly","K09535//DnaJ homolog subfamily C member 15","NP_037370.2//dnaJ homolog subfamily C member 15 [Homo sapiens]","2//1"]
[5676,1680,0.01,0.06,2.58496250072116,0.650790853783982,"*",0.499032,"PSG7","GO:0005576//extracellular region","NA","GO:0007565//female pregnancy","K06500//pregnancy specific beta-1-glycoprotein","NP_001193579.1//putative pregnancy-specific beta-1-glycoprotein 7 isoform 2 [Homo sapiens];XP_016789756.1//PREDICTED: putative pregnancy-specific beta-1-glycoprotein 7 [Pan troglodytes]","1//3;2//1"]
[10205,2791,0.01,0.06,2.58496250072116,0.65063150244858,"*",0.499032,"MPZL2","GO:0005856//cytoskeleton;GO:0016021//integral component of membrane","NA","GO:0009653//anatomical structure morphogenesis;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules","K06770//myelin protein zero","NP_005788.1//myelin protein zero-like protein 2 precursor [Homo sapiens]","3//A2MP1;2//1"]
[23493,2672,0.01,0.06,2.58496250072116,0.394208778932779,"*",0.249274,"HEY2","GO:0017053//transcriptional repressor complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016580//Sin3 complex;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0042826//histone deacetylase binding;GO:0046982//protein heterodimerization activity;GO:0000983//transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding;GO:0042803//protein homodimerization activity;GO:0046983//protein dimerization activity;GO:0035939//microsatellite binding;GO:0000988//transcription factor activity, protein binding;GO:0003700//DNA binding transcription factor activity;GO:0001102//RNA polymerase II activating transcription factor binding","GO:0003195//tricuspid valve formation;GO:0010667//negative regulation of cardiac muscle cell apoptotic process;GO:0014031//mesenchymal cell development;GO:0060948//cardiac vascular smooth muscle cell development;GO:0060977//coronary vasculature morphogenesis;GO:0001570//vasculogenesis;GO:0036304//umbilical cord morphogenesis;GO:0003215//cardiac right ventricle morphogenesis;GO:0060842//arterial endothelial cell differentiation;GO:0035912//dorsal aorta morphogenesis;GO:0003151//outflow tract morphogenesis;GO:0003150//muscular septum morphogenesis;GO:2001212//regulation of vasculogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045607//regulation of inner ear auditory receptor cell differentiation;GO:0007219//Notch signaling pathway;GO:0003222//ventricular trabecula myocardium morphogenesis;GO:0097084//vascular smooth muscle cell development;GO:0055015//ventricular cardiac muscle cell development;GO:2000678//negative regulation of transcription regulatory region DNA binding;GO:0006355//regulation of transcription, DNA-templated;GO:0014898//cardiac muscle hypertrophy in response to stress;GO:0060633//negative regulation of transcription initiation from RNA polymerase II promoter;GO:0061156//pulmonary artery morphogenesis;GO:0003184//pulmonary valve morphogenesis;GO:0003199//endocardial cushion to mesenchymal transition involved in heart valve formation;GO:0003214//cardiac left ventricle morphogenesis;GO:0035910//ascending aorta morphogenesis;GO:0045165//cell fate commitment;GO:0065004//protein-DNA complex assembly;GO:0010460//positive regulation of heart rate;GO:0060716//labyrinthine layer blood vessel development;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0006351//transcription, DNA-templated;GO:0060413//atrial septum morphogenesis;GO:0060347//heart trabecula formation;GO:0045746//negative regulation of Notch signaling pathway;GO:2000820//negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation;GO:0090102//cochlea development;GO:0009948//anterior/posterior axis specification","K09091//hairy and enhancer of split related with YRPW motif","NP_036391.1//hairy/enhancer-of-split related with YRPW motif protein 2 [Homo sapiens]","2//1"]
[728957,3683,0.01,0.06,2.58496250072116,0.226773249162011,"*",0.1245166,"ZNF705D","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_004452775.1//PREDICTED: zinc finger protein 596-like isoform X1 [Dasypus novemcinctus]","3//A2MP1"]
[3240,1301,0.01,0.06,2.58496250072116,0.650100894470723,"*",0.499032,"HP","GO:1904724//tertiary granule lumen;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0072562//blood microparticle;GO:0035580//specific granule lumen;GO:0031838//haptoglobin-hemoglobin complex;GO:0005576//extracellular region;GO:0071682//endocytic vesicle lumen","GO:0004252//serine-type endopeptidase activity;GO:0016209//antioxidant activity;GO:0030492//hemoglobin binding","GO:0006953//acute-phase response;GO:0051354//negative regulation of oxidoreductase activity;GO:0042742//defense response to bacterium;GO:0042542//response to hydrogen peroxide;GO:0006952//defense response;GO:0006898//receptor-mediated endocytosis;GO:0043312//neutrophil degranulation;GO:2000296//negative regulation of hydrogen peroxide catabolic process;GO:0010942//positive regulation of cell death","K16142//haptoglobin","EAW59197.1//haptoglobin, isoform CRA_d [Homo sapiens];EAW59194.1//haptoglobin, isoform CRA_a [Homo sapiens]","4;1//3;2//1"]
[28999,2539,0.01,0.06,2.58496250072116,0.394091733570863,"*",0.249274,"KLF15","NA","NA","NA","K09210//krueppel-like factor 15","XP_011511045.1//PREDICTED: Krueppel-like factor 15 isoform X1 [Homo sapiens]","3//A2MP1"]
[10017,1255,0.01,0.06,2.58496250072116,0.649941880799022,"*",0.499032,"BCL2L10","GO:0016020//membrane;GO:0031965//nuclear membrane;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane","GO:0089720//caspase binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity","GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0007283//spermatogenesis;GO:0007292//female gamete generation;GO:0043065//positive regulation of apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process","K18451//Bcl-2-like protein 10","NP_065129.1//bcl-2-like protein 10 isoform 2 [Homo sapiens];NP_001293097.1//bcl-2-like protein 10 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[9413,2138,0.01,0.06,2.58496250072116,0.394013741935484,"*",0.249274,"FAM189A2","NA","NA","NA","K02893//large subunit ribosomal protein L23Ae;K01201//glucosylceramidase [EC:3.2.1.45];K13751//solute carrier family 24 (sodium/potassium/calcium exchanger), member 3","NP_001334924.1//protein FAM189A2 isoform a [Homo sapiens]","1//3;4;2//1"]
[9823,2853,0.01,0.06,2.58496250072116,0.393779952136076,"*",0.249274,"ARMCX2","GO:0016021//integral component of membrane","NA","NA","K20493//leucine-rich repeat-containing protein 16","XP_007990504.1//PREDICTED: LOW QUALITY PROTEIN: armadillo repeat-containing X-linked protein 2 [Chlorocebus sabaeus]","6;1//3;3//A2MP1"]
[11314,1456,0.01,0.06,2.58496250072116,0.648197850707432,"*",0.499032,"CD300A","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0101003//ficolin-1-rich granule membrane;GO:0016021//integral component of membrane;GO:0070821//tertiary granule membrane;GO:0005886//plasma membrane","GO:0038023//signaling receptor activity;GO:0008429//phosphatidylethanolamine binding;GO:0001786//phosphatidylserine binding","GO:1902567//negative regulation of eosinophil activation;GO:0043407//negative regulation of MAP kinase activity;GO:0060101//negative regulation of phagocytosis, engulfment;GO:0043305//negative regulation of mast cell degranulation;GO:0051134//negative regulation of NK T cell activation;GO:0043312//neutrophil degranulation;GO:0050776//regulation of immune response;GO:0033007//negative regulation of mast cell activation involved in immune response;GO:2000417//negative regulation of eosinophil migration;GO:0032516//positive regulation of phosphoprotein phosphatase activity;GO:0048147//negative regulation of fibroblast proliferation;GO:0050856//regulation of T cell receptor signaling pathway;GO:1902564//negative regulation of neutrophil activation;GO:1902569//negative regulation of activation of Janus kinase activity;GO:0007155//cell adhesion;GO:0050859//negative regulation of B cell receptor signaling pathway;GO:0030889//negative regulation of B cell proliferation;GO:0034125//negative regulation of MyD88-dependent toll-like receptor signaling pathway","K06719//CD300 antigen","NP_001317386.1//CMRF35-like molecule 8 isoform 4 precursor [Homo sapiens];NP_009192.2//CMRF35-like molecule 8 isoform 1 precursor [Homo sapiens];NP_001243770.1//CMRF35-like molecule 8 isoform 2 precursor [Homo sapiens]","1//3;3//A2MP1"]
[29015,2650,0.01,0.06,2.58496250072116,0.392963868153558,"*",0.249274,"SLC43A3","GO:0016021//integral component of membrane","NA","GO:0055085//transmembrane transport","K08230//MFS transporter, LAT3 family, solute carrier family 43, member 3","NP_060081.1//solute carrier family 43 member 3 isoform 1 [Homo sapiens];XP_008950090.1//PREDICTED: solute carrier family 43 member 3 isoform X1 [Pan paniscus];XP_008950091.1//PREDICTED: solute carrier family 43 member 3 isoform X2 [Pan paniscus]","1//3;3//A2MP1;2//1"]
[7148,6237,0.05,0.3,2.58496250072116,0.0185247834046136,"*",0.00688736,"TNXB","GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005622//intracellular;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix","GO:0005201//extracellular matrix structural constituent;GO:0005178//integrin binding;GO:0008201//heparin binding","GO:0032963//collagen metabolic process;GO:0007155//cell adhesion;GO:0030036//actin cytoskeleton organization;GO:0030199//collagen fibril organization;GO:0048251//elastic fiber assembly","K06252//tenascin","NP_061978.6//tenascin-X isoform 1 precursor [Homo sapiens]","6;3//A2MP1"]
[121506,1388,0.01,0.06,2.58496250072116,0.645207379036827,"*",0.499032,"ERP27","GO:0005788//endoplasmic reticulum lumen","NA","NA","K20355//endoplasmic reticulum protein 27","XP_012357838.1//PREDICTED: endoplasmic reticulum resident protein 27 isoform X2 [Nomascus leucogenys];NP_689534.1//endoplasmic reticulum resident protein 27 isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[5449,1262,0.01,0.06,2.58496250072116,0.64473771983177,"*",0.499032,"POU1F1","GO:0005634//nucleus;GO:0005667//transcription factor complex","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003714//transcription corepressor activity;GO:0001105//RNA polymerase II transcription coactivator activity;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0003682//chromatin binding;GO:0043565//sequence-specific DNA binding;GO:0001102//RNA polymerase II activating transcription factor binding;GO:0003700//DNA binding transcription factor activity","GO:0006355//regulation of transcription, DNA-templated;GO:0043567//regulation of insulin-like growth factor receptor signaling pathway;GO:0006351//transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0060133//somatotropin secreting cell development;GO:0008340//determination of adult lifespan;GO:0051169//nuclear transport;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0001708//cell fate specification;GO:0032962//positive regulation of inositol trisphosphate biosynthetic process;GO:0040018//positive regulation of multicellular organism growth;GO:0030183//B cell differentiation;GO:0008285//negative regulation of cell proliferation;GO:0008284//positive regulation of cell proliferation","K09363//POU domain transcription factor, class 1","NP_000297.1//pituitary-specific positive transcription factor 1 isoform alpha [Homo sapiens];NP_001116229.1//pituitary-specific positive transcription factor 1 isoform beta [Homo sapiens]","3//A2MP1;2//1"]
[257062,2528,0.01,0.06,2.58496250072116,0.392499051355347,"*",0.249274,"CATSPERD","GO:0097228//sperm principal piece;GO:0005886//plasma membrane;GO:0036128//CatSper complex","NA","GO:0030317//flagellated sperm motility;GO:0035036//sperm-egg recognition;GO:0007275//multicellular organism development;GO:0048240//sperm capacitation;GO:0007283//spermatogenesis;GO:0032570//response to progesterone","K16895//cation channel sperm-associated protein subunit delta","NP_689997.3//cation channel sperm-associated protein subunit delta precursor [Homo sapiens]","3//A2MP1"]
[1187,2555,0.01,0.06,2.58496250072116,0.643800449685027,"*",0.499032,"CLCNKA","GO:0005887//integral component of plasma membrane;GO:0034707//chloride channel complex;GO:0005886//plasma membrane","GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0005247//voltage-gated chloride channel activity","GO:0006810//transport;GO:0034220//ion transmembrane transport;GO:0007588//excretion;GO:1902476//chloride transmembrane transport","K05018//chloride channel Kb","NP_001036169.1//chloride channel protein ClC-Ka isoform 2 [Homo sapiens];NP_001244068.1//chloride channel protein ClC-Ka isoform 3 [Homo sapiens];NP_004061.3//chloride channel protein ClC-Ka isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[9023,1378,0.01,0.06,2.58496250072116,0.643592537380914,"*",0.499032,"CH25H","GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0008395//steroid hydroxylase activity;GO:0005506//iron ion binding;GO:0001567//cholesterol 25-hydroxylase activity;GO:0016491//oxidoreductase activity","GO:0016126//sterol biosynthetic process;GO:0008203//cholesterol metabolic process;GO:0035754//B cell chemotaxis;GO:0008610//lipid biosynthetic process;GO:0006629//lipid metabolic process;GO:0006699//bile acid biosynthetic process","K10223//cholesterol 25-hydroxylase [EC:1.14.99.38]","NP_003947.1//cholesterol 25-hydroxylase [Homo sapiens]","3//A2MP1"]
[3467,1270,0.01,0.06,2.58496250072116,0.643488631578947,"*",0.499032,"IFNW1","GO:0005615//extracellular space","GO:0005132//type I interferon receptor binding;GO:0005125//cytokine activity;GO:0005126//cytokine receptor binding","GO:0051607//defense response to virus;GO:0043330//response to exogenous dsRNA;GO:0007050//cell cycle arrest;GO:0002250//adaptive immune response;GO:0042100//B cell proliferation;GO:0006959//humoral immune response;GO:0002286//T cell activation involved in immune response;GO:0033141//positive regulation of peptidyl-serine phosphorylation of STAT protein;GO:0002323//natural killer cell activation involved in immune response;GO:0030183//B cell differentiation;GO:0019221//cytokine-mediated signaling pathway;GO:0009615//response to virus;GO:0045087//innate immune response","K05440//interferon omega","XP_016816170.1//PREDICTED: interferon omega-1 [Pan troglodytes]","2//1"]
[282890,2517,0.03,0.18,2.58496250072116,0.140007482468021,"*",0.0698898,"ZNF311","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","XP_021571051.1//zinc finger protein 311 [Carlito syrichta];XP_004447449.1//PREDICTED: zinc finger protein 311 isoform X1 [Dasypus novemcinctus]","1//3;3//A2MP1"]
[11126,1633,0.05,0.3,2.58496250072116,0.139989926670846,"*",0.0698898,"CD160","GO:0016021//integral component of membrane;GO:0046658//anchored component of plasma membrane;GO:0005886//plasma membrane","GO:0004872//receptor activity;GO:0032393//MHC class I receptor activity;GO:0005102//receptor binding","GO:0050829//defense response to Gram-negative bacterium;GO:0008283//cell proliferation;GO:0007166//cell surface receptor signaling pathway;GO:0006968//cellular defense response;GO:0050776//regulation of immune response","K06542//CD160 antigen","NP_008984.1//CD160 antigen precursor [Homo sapiens]","3//A2MP1"]
[284366,1438,0.01,0.06,2.58496250072116,0.640284109879518,"*",0.499032,"KLK9","GO:0005576//extracellular region","GO:0004252//serine-type endopeptidase activity","NA","K09618//kallikrein 9 [EC:3.4.21.-]","XP_011936429.1//PREDICTED: kallikrein-9 [Cercocebus atys]","1//3"]
[6364,851,0.49,2.93,2.58004701030704,{"v":5.68831654653465E-5,"d":"5.69E-05"},"Up",{"v":1.258808e-05,"d":"1.26E-05"},"CCL20","GO:0005615//extracellular space;GO:0005622//intracellular;GO:0005576//extracellular region","GO:0048020//CCR chemokine receptor binding;GO:0008009//chemokine activity;GO:0031731//CCR6 chemokine receptor binding","GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0072678//T cell migration;GO:0071222//cellular response to lipopolysaccharide;GO:0043547//positive regulation of GTPase activity;GO:0042742//defense response to bacterium;GO:0071356//cellular response to tumor necrosis factor;GO:0035584//calcium-mediated signaling using intracellular calcium source;GO:0071346//cellular response to interferon-gamma;GO:0051770//positive regulation of nitric-oxide synthase biosynthetic process;GO:0071347//cellular response to interleukin-1;GO:0060326//cell chemotaxis;GO:0002548//monocyte chemotaxis;GO:0006935//chemotaxis;GO:2000406//positive regulation of T cell migration;GO:0050726//positive regulation of interleukin-1 alpha biosynthetic process;GO:0048247//lymphocyte chemotaxis;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007165//signal transduction;GO:0030593//neutrophil chemotaxis;GO:0042060//wound healing;GO:0007267//cell-cell signaling;GO:0071223//cellular response to lipoteichoic acid;GO:0070098//chemokine-mediated signaling pathway;GO:0031640//killing of cells of other organism;GO:0006954//inflammatory response;GO:0072679//thymocyte migration;GO:0006955//immune response;GO:0070374//positive regulation of ERK1 and ERK2 cascade","K14625//C-C motif chemokine 20","NP_001123518.1//C-C motif chemokine 20 isoform 2 precursor [Homo sapiens];NP_004582.1//C-C motif chemokine 20 isoform 1 precursor [Homo sapiens]","1//3;2//1"]
[2634,4148,0.29,1.72,2.56828375957453,{"v":2.23850927511886E-13,"d":"2.24E-13"},"Up",{"v":1.768498E-14,"d":"1.77E-14"},"GBP2","GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0015629//actin cytoskeleton","GO:0005525//GTP binding;GO:0003924//GTPase activity","NA","K20897//guanylate-binding protein 2","XP_007976231.1//PREDICTED: interferon-induced guanylate-binding protein 2 [Chlorocebus sabaeus]",4]
[10379,1699,9.78,57.66,2.55966446654267,{"v":2.94495025641025e-172,"d":"2.94E-172"},"Up",{"v":7.19e-175,"d":"7.19E-175"},"IRF9","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0003700//DNA binding transcription factor activity;GO:0001047//core promoter binding","GO:0060333//interferon-gamma-mediated signaling pathway;GO:0060337//type I interferon signaling pathway;GO:0051607//defense response to virus;GO:0006351//transcription, DNA-templated;GO:0007166//cell surface receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter","K04693//interferon regulatory factor 9","NP_006075.3//interferon regulatory factor 9 [Homo sapiens]",4]
[7098,3057,0.05,0.29,2.53605290024021,0.0321612377117712,"*",0.01281094,"TLR3","GO:0016020//membrane;GO:0005765//lysosomal membrane;GO:0010008//endosome membrane;GO:0005622//intracellular;GO:0036020//endolysosome membrane;GO:0005737//cytoplasm;GO:0000139//Golgi membrane;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005769//early endosome","GO:0004872//receptor activity;GO:0042802//identical protein binding;GO:0004888//transmembrane signaling receptor activity;GO:0003725//double-stranded RNA binding","GO:0046330//positive regulation of JNK cascade;GO:0097191//extrinsic apoptotic signaling pathway;GO:0071260//cellular response to mechanical stimulus;GO:0035690//cellular response to drug;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0097190//apoptotic signaling pathway;GO:0034123//positive regulation of toll-like receptor signaling pathway;GO:0008584//male gonad development;GO:0071346//cellular response to interferon-gamma;GO:0032760//positive regulation of tumor necrosis factor production;GO:0043065//positive regulation of apoptotic process;GO:0035458//cellular response to interferon-beta;GO:0045087//innate immune response;GO:0007165//signal transduction;GO:0032757//positive regulation of interleukin-8 production;GO:0007250//activation of NF-kappaB-inducing kinase activity;GO:0010628//positive regulation of gene expression;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045671//negative regulation of osteoclast differentiation;GO:0032755//positive regulation of interleukin-6 production;GO:0007252//I-kappaB phosphorylation;GO:0043330//response to exogenous dsRNA;GO:0042742//defense response to bacterium;GO:0050729//positive regulation of inflammatory response;GO:0006972//hyperosmotic response;GO:0043331//response to dsRNA;GO:0032735//positive regulation of interleukin-12 production;GO:0045078//positive regulation of interferon-gamma biosynthetic process;GO:0034346//positive regulation of type III interferon production;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0034138//toll-like receptor 3 signaling pathway;GO:0032728//positive regulation of interferon-beta production;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0009597//detection of virus;GO:0051607//defense response to virus;GO:0071360//cellular response to exogenous dsRNA;GO:0097527//necroptotic signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:0042346//positive regulation of NF-kappaB import into nucleus;GO:0006954//inflammatory response;GO:0034128//negative regulation of MyD88-independent toll-like receptor signaling pathway;GO:0045359//positive regulation of interferon-beta biosynthetic process;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0045080//positive regulation of chemokine biosynthetic process;GO:0070266//necroptotic process;GO:0002730//regulation of dendritic cell cytokine production;GO:0002282//microglial cell activation involved in immune response;GO:0032722//positive regulation of chemokine production;GO:0045356//positive regulation of interferon-alpha biosynthetic process","K05401//toll-like receptor 3","NP_003256.1//toll-like receptor 3 precursor [Homo sapiens]","2//1"]
[80380,2418,0.03,0.17,2.50250034052918,0.226938461183459,"*",0.1243658,"PDCD1LG2","NA","NA","NA","K06708//programmed cell death 1 ligand 2","XP_010363386.1//PREDICTED: programmed cell death 1 ligand 2 isoform X1 [Rhinopithecus roxellana]","3//A2MP1"]
[3601,1689,1.08,5.82,2.42998784074482,{"v":9.81377108722109e-17,"d":"9.81E-17"},"Up",{"v":6.05758e-18,"d":"6.06E-18"},"IL15RA","GO:0031965//nuclear membrane;GO:0005615//extracellular space;GO:0031410//cytoplasmic vesicle;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0000139//Golgi membrane;GO:0030659//cytoplasmic vesicle membrane","GO:0004896//cytokine receptor activity;GO:0004871//signal transducer activity","GO:0010977//negative regulation of neuron projection development;GO:0007259//JAK-STAT cascade;GO:0007165//signal transduction;GO:0008283//cell proliferation;GO:0031667//response to nutrient levels;GO:0032825//positive regulation of natural killer cell differentiation","K05074//interleukin 15 receptor alpha","XP_001146125.2//PREDICTED: interleukin-15 receptor subunit alpha isoform X1 [Pan troglodytes];XP_011517771.1//PREDICTED: interleukin-15 receptor subunit alpha isoform X9 [Homo sapiens];XP_003312489.1//PREDICTED: interleukin-15 receptor subunit alpha isoform X3 [Pan troglodytes];NP_001338024.1//interleukin-15 receptor subunit alpha isoform 5 [Homo sapiens];NP_001243694.1//interleukin-15 receptor subunit alpha isoform 4 [Homo sapiens];XP_016871684.1//PREDICTED: interleukin-15 receptor subunit alpha isoform X11 [Homo sapiens];XP_011517768.1//PREDICTED: interleukin-15 receptor subunit alpha isoform X6 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[64386,3565,0.71,3.72,2.38941169160335,{"v":3.82628464842105E-22,"d":"3.83E-22"},"Up",{"v":1.592888e-23,"d":"1.59E-23"},"MMP25","GO:0031012//extracellular matrix;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding","GO:0060022//hard palate development;GO:0006954//inflammatory response","K08003//matrix metalloproteinase-25 (membrane-inserted) [EC:3.4.24.-]","XP_017719384.1//PREDICTED: matrix metalloproteinase-25 [Rhinopithecus bieti]",4]
[80271,3398,4.91,25.56,2.3800929066323,{"v":2.10853804875e-142,"d":"2.11E-142"},"Up",{"v":8.44788e-145,"d":"8.45E-145"},"ITPKC","GO:0005829//cytosol;GO:0016607//nuclear speck","GO:0005524//ATP binding;GO:0008440//inositol-1,4,5-trisphosphate 3-kinase activity;GO:0005516//calmodulin binding","GO:0043647//inositol phosphate metabolic process","K00911//1D-myo-inositol-triphosphate 3-kinase [EC:2.7.1.127]","NP_079470.1//inositol-trisphosphate 3-kinase C [Homo sapiens]","2//1"]
[5880,1538,0.05,0.26,2.37851162325373,0.226990320978062,"*",0.1243658,"RAC2","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005925//focal adhesion;GO:0005635//nuclear envelope;GO:0005622//intracellular;GO:0030670//phagocytic vesicle membrane;GO:0005737//cytoplasm;GO:0030027//lamellipodium;GO:0005884//actin filament;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0019887//protein kinase regulator activity;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:1902622//regulation of neutrophil migration;GO:0071593//lymphocyte aggregation;GO:1903955//positive regulation of protein targeting to mitochondrion;GO:0030168//platelet activation;GO:0060263//regulation of respiratory burst;GO:0007015//actin filament organization;GO:0042129//regulation of T cell proliferation;GO:0007264//small GTPase mediated signal transduction;GO:0010310//regulation of hydrogen peroxide metabolic process;GO:0043304//regulation of mast cell degranulation;GO:0060753//regulation of mast cell chemotaxis;GO:0006935//chemotaxis;GO:0030031//cell projection assembly;GO:0045453//bone resorption;GO:0007186//G-protein coupled receptor signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0007165//signal transduction;GO:0090023//positive regulation of neutrophil chemotaxis;GO:0010592//positive regulation of lamellipodium assembly;GO:0010810//regulation of cell-substrate adhesion;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0008284//positive regulation of cell proliferation","K07860//Ras-related C3 botulinum toxin substrate 2","AAD27003.1//HSPC022 [Homo sapiens]",4]
[3872,1574,0.05,0.26,2.37851162325373,0.226912540171331,"*",0.1243658,"KRT17","GO:0070062//extracellular exosome;GO:0045111//intermediate filament cytoskeleton;GO:0005829//cytosol;GO:0071944//cell periphery;GO:0005882//intermediate filament;GO:0005737//cytoplasm","GO:0042289//MHC class II protein binding;GO:0005198//structural molecule activity;GO:0005200//structural constituent of cytoskeleton;GO:0032395//MHC class II receptor activity","GO:0007165//signal transduction;GO:0045109//intermediate filament organization;GO:0045727//positive regulation of translation;GO:0030307//positive regulation of cell growth;GO:0031424//keratinization;GO:0070268//cornification;GO:0008544//epidermis development;GO:0031069//hair follicle morphogenesis;GO:0051798//positive regulation of hair follicle development","K07604//type I keratin, acidic","XP_008010900.1//PREDICTED: keratin, type I cytoskeletal 17 [Chlorocebus sabaeus]","2//1"]
[3936,3808,0.06,0.31,2.36923380966572,0.012319214230226,"*",0.0043681,"LCP1","NA","NA","NA","K17276//plastin-2","XP_010356391.1//PREDICTED: plastin-2 [Rhinopithecus roxellana]",4]
[112476,2915,1.08,5.57,2.36664601517656,{"v":2.59790361967213E-30,"d":"2.60E-30"},"Up",{"v":6.94444e-32,"d":"6.94E-32"},"PRRT2","GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0045202//synapse;GO:0005886//plasma membrane;GO:0043005//neuron projection","GO:0017124//SH3 domain binding","GO:0050884//neuromuscular process controlling posture;GO:0009607//response to biotic stimulus","K00901//diacylglycerol kinase (ATP) [EC:2.7.1.107]","NP_001243371.1//proline-rich transmembrane protein 2 isoform 2 [Homo sapiens];XP_012360791.1//PREDICTED: proline-rich transmembrane protein 2 isoform X1 [Nomascus leucogenys];NP_660282.2//proline-rich transmembrane protein 2 isoform 1 [Homo sapiens]","1//3;2//1"]
[83666,4724,2.89,14.84,2.36034969412012,{"v":5.8524172e-99,"d":"5.85E-99"},"Up",{"v":3.59044e-101,"d":"3.59E-101"},"PARP9","GO:0016020//membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043234//protein complex;GO:0005739//mitochondrion;GO:0090734//site of DNA damage","GO:0042393//histone binding;GO:0097677//STAT family protein binding;GO:0003950//NAD+ ADP-ribosyltransferase activity;GO:0072570//ADP-D-ribose binding;GO:0004857//enzyme inhibitor activity;GO:0044389//ubiquitin-like protein ligase binding;GO:0001191//transcriptional repressor activity, RNA polymerase II transcription factor binding;GO:0019899//enzyme binding","GO:1900182//positive regulation of protein localization to nucleus;GO:0034356//NAD biosynthesis via nicotinamide riboside salvage pathway;GO:0016477//cell migration;GO:0060335//positive regulation of interferon-gamma-mediated signaling pathway;GO:0035563//positive regulation of chromatin binding;GO:0010629//negative regulation of gene expression;GO:0010608//posttranscriptional regulation of gene expression;GO:2001034//positive regulation of double-strand break repair via nonhomologous end joining;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006302//double-strand break repair;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0060330//regulation of response to interferon-gamma;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0043086//negative regulation of catalytic activity;GO:0002230//positive regulation of defense response to virus by host;GO:0006471//protein ADP-ribosylation","K15260//poly [ADP-ribose] polymerase 9 [EC:2.4.2.30]","NP_113646.2//poly [ADP-ribose] polymerase 9 isoform a [Homo sapiens];NP_001139575.1//poly [ADP-ribose] polymerase 9 isoform b [Homo sapiens];NP_001139578.1//poly [ADP-ribose] polymerase 9 isoform c [Homo sapiens]","1//3;2//1"]
[467,2134,1.27,6.49,2.35338998122697,{"v":9.09561891970803e-22,"d":"9.10E-22"},"Up",{"v":3.9004e-23,"d":"3.90E-23"},"ATF3","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:1990622//CHOP-ATF3 complex","GO:0003677//DNA binding;GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003714//transcription corepressor activity;GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0042803//protein homodimerization activity;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0034198//cellular response to amino acid starvation;GO:1903984//positive regulation of TRAIL-activated apoptotic signaling pathway;GO:0006094//gluconeogenesis;GO:1990440//positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0035914//skeletal muscle cell differentiation;GO:0061394//regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0036499//PERK-mediated unfolded protein response;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0008284//positive regulation of cell proliferation","K09032//activating transcription factor 3","OBS69098.1//hypothetical protein A6R68_02380 [Neotoma lepida];XP_007986692.1//PREDICTED: cyclic AMP-dependent transcription factor ATF-3 [Chlorocebus sabaeus];NP_001035709.1//cyclic AMP-dependent transcription factor ATF-3 isoform 2 [Homo sapiens];NP_001193415.1//cyclic AMP-dependent transcription factor ATF-3 isoform 5 [Homo sapiens]","3//A2MP1;2//1"]
[5745,2007,0.04,0.2,2.32192809488736,0.2270681551263,"*",0.1243658,"PTH1R","GO:0070062//extracellular exosome;GO:0016323//basolateral plasma membrane;GO:0005634//nucleus;GO:0016324//apical plasma membrane;GO:0031526//brush border membrane;GO:0005622//intracellular;GO:0005737//cytoplasm;GO:0043235//receptor complex;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004991//parathyroid hormone receptor activity;GO:0017046//peptide hormone binding;GO:0043621//protein self-association","GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0007166//cell surface receptor signaling pathway;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0006874//cellular calcium ion homeostasis;GO:0008285//negative regulation of cell proliferation;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0045453//bone resorption;GO:0007186//G-protein coupled receptor signaling pathway;GO:0030282//bone mineralization;GO:0007568//aging;GO:0060732//positive regulation of inositol phosphate biosynthetic process;GO:0048469//cell maturation;GO:0002062//chondrocyte differentiation;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0001501//skeletal system development;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0002076//osteoblast development;GO:0008284//positive regulation of cell proliferation","K04585//parathyroid hormone receptor 1","NP_000307.1//parathyroid hormone/parathyroid hormone-related peptide receptor precursor [Homo sapiens]","1//3;2//1"]
[8528,1733,0.01,0.05,2.32192809488736,0.655661882546471,"*",0.499032,"DDO","GO:0005782//peroxisomal matrix;GO:0005777//peroxisome","GO:0008445//D-aspartate oxidase activity;GO:0005102//receptor binding;GO:0048037//cofactor binding;GO:0071949//FAD binding","GO:0019478//D-amino acid catabolic process;GO:0007320//insemination;GO:0042445//hormone metabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0006531//aspartate metabolic process;GO:0007625//grooming behavior;GO:0006533//aspartate catabolic process","K00272//D-aspartate oxidase [EC:1.4.3.1]","NP_003640.2//D-aspartate oxidase isoform a [Homo sapiens];NP_004023.2//D-aspartate oxidase isoform b [Homo sapiens]","2//1"]
[92369,2945,0.01,0.05,2.32192809488736,0.395579463143255,"*",0.249274,"SPSB4","GO:0005829//cytosol;GO:0005622//intracellular","NA","GO:0043687//post-translational protein modification;GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction","K10343//SPRY domain-containing SOCS box protein 1/4","NP_543138.1//SPRY domain-containing SOCS box protein 4 [Homo sapiens]","2//1"]
[3167,1628,0.01,0.05,2.32192809488736,0.653726190585534,"*",0.499032,"HMX2","GO:0005634//nucleus","GO:0043565//sequence-specific DNA binding","GO:0048026//positive regulation of mRNA splicing, via spliceosome;GO:0042472//inner ear morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0007420//brain development;GO:0008284//positive regulation of cell proliferation","K09349//homeobox protein Nkx-5","XP_007962514.1//PREDICTED: homeobox protein HMX2 [Chlorocebus sabaeus]","1//3"]
[1361,1655,0.01,0.05,2.32192809488736,0.653244052118332,"*",0.499032,"CPB2","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005623//cell;GO:0005576//extracellular region","GO:0008270//zinc ion binding;GO:0004181//metallocarboxypeptidase activity","GO:0042730//fibrinolysis;GO:0042493//response to drug;GO:0030449//regulation of complement activation;GO:0097421//liver regeneration;GO:0007596//blood coagulation;GO:2000346//negative regulation of hepatocyte proliferation;GO:0010757//negative regulation of plasminogen activation;GO:0003331//positive regulation of extracellular matrix constituent secretion;GO:0009408//response to heat;GO:0051918//negative regulation of fibrinolysis;GO:0071333//cellular response to glucose stimulus;GO:0006508//proteolysis","K01300//carboxypeptidase B2 [EC:3.4.17.20]","NP_001265470.1//carboxypeptidase B2 isoform 2 preproprotein [Homo sapiens];NP_001863.3//carboxypeptidase B2 isoform 1 preproprotein [Homo sapiens]","4;1//3"]
[55350,1723,0.01,0.05,2.32192809488736,0.653137006800492,"*",0.499032,"VNN3","NA","NA","NA","K08069//pantetheine hydrolase [EC:3.5.1.92]","CAB76824.1//VNN3 protein [Homo sapiens]","1//3"]
[139728,1522,0.01,0.05,2.32192809488736,0.652602306017192,"*",0.499032,"PNCK","GO:0005634//nucleus;GO:0005622//intracellular;GO:0005737//cytoplasm","GO:0005524//ATP binding;GO:0004683//calmodulin-dependent protein kinase activity;GO:0005516//calmodulin binding","GO:0018107//peptidyl-threonine phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0035556//intracellular signal transduction","K08795//pregnancy upregulated non-ubiquitously expressed CaM kinase [EC:2.7.11.17]","NP_001129212.1//calcium/calmodulin-dependent protein kinase type 1B isoform b [Homo sapiens];NP_001034671.3//calcium/calmodulin-dependent protein kinase type 1B isoform a [Homo sapiens]","1//3;3//A2MP1"]
[3854,2331,0.01,0.05,2.32192809488736,0.652548884086444,"*",0.499032,"KRT6B","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0045095//keratin filament","GO:0005198//structural molecule activity;GO:0005200//structural constituent of cytoskeleton","GO:0031424//keratinization;GO:0007398//ectoderm development;GO:0070268//cornification","K07605//type II keratin, basic","NP_005546.2//keratin, type II cytoskeletal 6B [Homo sapiens]","3//A2MP1"]
[921,3180,0.01,0.05,2.32192809488736,0.39479505016855,"*",0.249274,"CD5","GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005044//scavenger receptor activity;GO:0004872//receptor activity;GO:0004888//transmembrane signaling receptor activity","GO:0008283//cell proliferation;GO:0097190//apoptotic signaling pathway;GO:0008037//cell recognition;GO:0031295//T cell costimulation","K06455//T-cell surface glycoprotein CD5","NP_055022.2//T-cell surface glycoprotein CD5 isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[221188,3310,0.01,0.05,2.32192809488736,0.394755911172797,"*",0.249274,"ADGRG5","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004930//G-protein coupled receptor activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0007166//cell surface receptor signaling pathway","K08459//G protein-coupled receptor 114","NP_001305410.1//adhesion G-protein coupled receptor G5 isoform 2 precursor [Homo sapiens];NP_722579.1//adhesion G-protein coupled receptor G5 isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1;2//1"]
[2128,3049,0.01,0.05,2.32192809488736,0.394677656457528,"*",0.249274,"EVX1","GO:0005654//nucleoplasm","GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0006355//regulation of transcription, DNA-templated;GO:0021913//regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0009792//embryo development ending in birth or egg hatching","K09320//homeobox even-skipped homolog protein","NP_001980.1//homeobox even-skipped homolog protein 1 isoform 1 [Homo sapiens]","4;1//3"]
[9104,1637,0.01,0.05,2.32192809488736,0.651801894358136,"*",0.499032,"RGN","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0004341//gluconolactonase activity;GO:0005509//calcium ion binding;GO:0008270//zinc ion binding;GO:0030234//enzyme regulator activity","GO:0010867//positive regulation of triglyceride biosynthetic process;GO:0097421//liver regeneration;GO:0001822//kidney development;GO:0032515//negative regulation of phosphoprotein phosphatase activity;GO:1901671//positive regulation of superoxide dismutase activity;GO:0043547//positive regulation of GTPase activity;GO:0007283//spermatogenesis;GO:1903634//negative regulation of leucine-tRNA ligase activity;GO:1903611//negative regulation of calcium-dependent ATPase activity;GO:0019853//L-ascorbic acid biosynthetic process;GO:1903629//positive regulation of dUTP diphosphatase activity;GO:1901318//negative regulation of flagellated sperm motility;GO:0006874//cellular calcium ion homeostasis;GO:0010922//positive regulation of phosphatase activity;GO:0010907//positive regulation of glucose metabolic process;GO:0043066//negative regulation of apoptotic process;GO:1903011//negative regulation of bone development;GO:0045019//negative regulation of nitric oxide biosynthetic process;GO:1902679//negative regulation of RNA biosynthetic process;GO:0007568//aging;GO:2000279//negative regulation of DNA biosynthetic process;GO:0006469//negative regulation of protein kinase activity;GO:0045723//positive regulation of fatty acid biosynthetic process;GO:1901896//positive regulation of calcium-transporting ATPase activity;GO:0032781//positive regulation of ATPase activity;GO:0050848//regulation of calcium-mediated signaling;GO:1903625//negative regulation of DNA catabolic process;GO:0050680//negative regulation of epithelial cell proliferation;GO:0034260//negative regulation of GTPase activity;GO:0051344//negative regulation of cyclic-nucleotide phosphodiesterase activity;GO:1903052//positive regulation of proteolysis involved in cellular protein catabolic process","K01053//gluconolactonase [EC:3.1.1.17]","NP_001269778.1//regucalcin isoform 3 [Homo sapiens];NP_004674.1//regucalcin isoform 1 [Homo sapiens]","1//3;3//A2MP1;5"]
[56159,3151,0.04,0.2,2.32192809488736,0.085163198735569,"*",0.038791,"TEX11","GO:0000801//central element","NA","GO:0006311//meiotic gene conversion;GO:0000712//resolution of meiotic recombination intermediates;GO:0009566//fertilization;GO:0043066//negative regulation of apoptotic process;GO:0008584//male gonad development;GO:0007130//synaptonemal complex assembly;GO:0007131//reciprocal meiotic recombination;GO:0051026//chiasma assembly;GO:0007060//male meiosis chromosome segregation","K22069//LYR motif-containing protein 4;K12581//CCR4-NOT transcription complex subunit 7/8;K16506//protocadherin Fat 1/2/3;K18674//N-acetylgalactosamine kinase [EC:2.7.1.157];K07994//matrix metalloproteinase-13 (collagenase 3) [EC:3.4.24.-]","NP_001003811.1//testis-expressed protein 11 isoform 1 [Homo sapiens];NP_112566.2//testis-expressed protein 11 isoform 2 [Homo sapiens]","1//3;2//1"]
[7712,1695,0.01,0.05,2.32192809488736,0.65137581042654,"*",0.499032,"ZNF157","GO:0005622//intracellular","GO:0046872//metal ion binding;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","XP_012786440.1//PREDICTED: zinc finger protein 260-like [Ochotona princeps]","3//A2MP1"]
[3355,3242,0.01,0.05,2.32192809488736,0.394325893840364,"*",0.249274,"HTR1F","GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane","GO:0051378//serotonin binding;GO:0004993//G-protein coupled serotonin receptor activity;GO:0030594//neurotransmitter receptor activity","GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0007268//chemical synaptic transmission;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger","K04153//5-hydroxytryptamine receptor 1","NP_000857.1//5-hydroxytryptamine receptor 1F [Homo sapiens]","1//3;4"]
[7568,3073,0.01,0.05,2.32192809488736,0.394286847806714,"*",0.249274,"ZNF20","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_021532378.1//zinc finger protein 433 isoform X5 [Aotus nancymaae]","1//3;3//A2MP1"]
[79652,1647,0.01,0.05,2.32192809488736,0.650578402676895,"*",0.499032,"TMEM204","GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005912//adherens junction","NA","GO:0001945//lymph vessel development;GO:0051145//smooth muscle cell differentiation;GO:0030947//regulation of vascular endothelial growth factor receptor signaling pathway","NA","NP_078876.2//transmembrane protein 204 precursor [Homo sapiens]","1//3;5"]
[9421,1749,0.01,0.05,2.32192809488736,0.649782944897294,"*",0.499032,"HAND1","GO:0090575//RNA polymerase II transcription factor complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003714//transcription corepressor activity;GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0043425//bHLH transcription factor binding;GO:0003713//transcription coactivator activity;GO:0008134//transcription factor binding;GO:0019899//enzyme binding","GO:0003219//cardiac right ventricle formation;GO:0001829//trophectodermal cell differentiation;GO:0043433//negative regulation of DNA binding transcription factor activity;GO:0060485//mesenchyme development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0001707//mesoderm formation;GO:0001824//blastocyst development;GO:0060536//cartilage morphogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0060411//cardiac septum morphogenesis;GO:0001525//angiogenesis;GO:0007507//heart development;GO:1903026//negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003218//cardiac left ventricle formation;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0035050//embryonic heart tube development;GO:0060707//trophoblast giant cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0042475//odontogenesis of dentin-containing tooth;GO:0001947//heart looping;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0003144//embryonic heart tube formation","K09071//heart-and neural crest derivatives-expressed protein 1","NP_004812.1//heart- and neural crest derivatives-expressed protein 1 [Homo sapiens]","2//1"]
[56123,3503,0.01,0.05,2.32192809488736,0.394052733894112,"*",0.249274,"PCDHB13","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane","GO:0005509//calcium ion binding","GO:0007416//synapse assembly;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007268//chemical synaptic transmission;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules","K16494//protocadherin beta","NP_061756.1//protocadherin beta-13 precursor [Homo sapiens]","3//A2MP1"]
[100506736,1767,0.01,0.05,2.32192809488736,0.649412396578411,"*",0.499032,"SLFN12L","GO:0016021//integral component of membrane","GO:0005524//ATP binding","NA","NA","NP_001182719.1//schlafen family member 12-like [Homo sapiens]","1//3"]
[136259,1480,0.01,0.05,2.32192809488736,0.64925371949829,"*",0.499032,"KLF14","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003676//nucleic acid binding","GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:1902070//positive regulation of sphingolipid mediated signaling pathway","K09208//krueppel-like factor 9/13/14/16","NP_619638.2//Krueppel-like factor 14 [Homo sapiens]","3//A2MP1"]
[340654,1484,0.01,0.05,2.32192809488736,0.649042270639961,"*",0.499032,"LIPM","NA","GO:0016788//hydrolase activity, acting on ester bonds","GO:0016042//lipid catabolic process","K19406//lipase-like abhydrolase domain-containing protein 3 [EC:3.1.1.-]","XP_004049794.1//PREDICTED: lipase member M isoform X1 [Gorilla gorilla gorilla]","1//3"]
[3791,6055,0.01,0.05,2.32192809488736,0.226618225863051,"*",0.1245166,"KDR","GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0030054//cell junction;GO:0005768//endosome;GO:0097443//sorting endosome;GO:0005887//integral component of plasma membrane;GO:0045121//membrane raft;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005769//early endosome","GO:0038085//vascular endothelial growth factor binding;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0019838//growth factor binding;GO:0004716//signal transducer, downstream of receptor, with protein tyrosine kinase activity;GO:0005021//vascular endothelial growth factor-activated receptor activity;GO:0051879//Hsp90 protein binding;GO:0004713//protein tyrosine kinase activity;GO:0005178//integrin binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity","GO:0030335//positive regulation of cell migration;GO:0043491//protein kinase B signaling;GO:0010595//positive regulation of endothelial cell migration;GO:0070371//ERK1 and ERK2 cascade;GO:0051901//positive regulation of mitochondrial depolarization;GO:0045766//positive regulation of angiogenesis;GO:0001570//vasculogenesis;GO:0001525//angiogenesis;GO:0051894//positive regulation of focal adhesion assembly;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0043066//negative regulation of apoptotic process;GO:0016032//viral process;GO:0008360//regulation of cell shape;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:0046777//protein autophosphorylation;GO:0030198//extracellular matrix organization;GO:0038083//peptidyl-tyrosine autophosphorylation;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0035584//calcium-mediated signaling using intracellular calcium source;GO:0038033//positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0002042//cell migration involved in sprouting angiogenesis;GO:0050927//positive regulation of positive chemotaxis;GO:0035162//embryonic hemopoiesis;GO:0051770//positive regulation of nitric-oxide synthase biosynthetic process;GO:0001934//positive regulation of protein phosphorylation;GO:0001938//positive regulation of endothelial cell proliferation;GO:0003158//endothelium development;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0090141//positive regulation of mitochondrial fission;GO:2001214//positive regulation of vasculogenesis;GO:0016239//positive regulation of macroautophagy;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0043410//positive regulation of MAPK cascade;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0008284//positive regulation of cell proliferation","K05098//kinase insert domain protein receptor [EC:2.7.10.1]","BAD93138.1//kinase insert domain receptor (a type III receptor tyrosine kinase) variant, partial [Homo sapiens]","2//1"]
[348303,1629,0.01,0.05,2.32192809488736,0.648567013912619,"*",0.499032,"SELENOV","NA","NA","NA","K11661//helicase SRCAP [EC:3.6.4.-];K06051//delta","XP_016802414.1//PREDICTED: selenoprotein V-like isoform X1 [Pan troglodytes]","1//3"]
[121214,1765,0.01,0.05,2.32192809488736,0.648303283018868,"*",0.499032,"SDR9C7","GO:0005730//nucleolus;GO:0005829//cytosol","GO:0004745//retinol dehydrogenase activity","GO:0055114//oxidation-reduction process","K11154//retinol dehydrogenase 16 [EC:1.1.1.-];K13369//17beta-estradiol 17-dehydrogenase / all-trans-retinol dehydrogenase (NAD+) / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:1.1.1.62 1.1.1.105 1.1.1.239]","NP_683695.1//short-chain dehydrogenase/reductase family 9C member 7 [Homo sapiens]","2//1"]
[3351,3175,0.01,0.05,2.32192809488736,0.393585339132154,"*",0.249274,"HTR1B","GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0051378//serotonin binding;GO:0004993//G-protein coupled serotonin receptor activity;GO:0008144//drug binding;GO:0030594//neurotransmitter receptor activity","GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0007198//adenylate cyclase-inhibiting serotonin receptor signaling pathway;GO:0050795//regulation of behavior;GO:0035690//cellular response to drug;GO:0042310//vasoconstriction;GO:0014059//regulation of dopamine secretion;GO:0045471//response to ethanol;GO:1904707//positive regulation of vascular smooth muscle cell proliferation;GO:0014063//negative regulation of serotonin secretion;GO:0032229//negative regulation of synaptic transmission, GABAergic;GO:0071502//cellular response to temperature stimulus;GO:0042756//drinking behavior;GO:0051967//negative regulation of synaptic transmission, glutamatergic;GO:0030818//negative regulation of cAMP biosynthetic process;GO:0051385//response to mineralocorticoid;GO:0042493//response to drug;GO:0007631//feeding behavior;GO:0007268//chemical synaptic transmission;GO:0002031//G-protein coupled receptor internalization;GO:0046849//bone remodeling;GO:0042220//response to cocaine;GO:0071312//cellular response to alkaloid;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger","K04153//5-hydroxytryptamine receptor 1","NP_000854.1//5-hydroxytryptamine receptor 1B [Homo sapiens]","2//1"]
[100133251,1587,0.01,0.05,2.32192809488736,0.999970998684128,"*",0.999032,"PRR23D2","NA","NA","NA","NA","NP_001269407.1//proline-rich protein 23D2 [Homo sapiens]","1//3"]
[55843,1774,0.01,0.05,2.32192809488736,0.647145410618607,"*",0.499032,"ARHGAP15","GO:0016020//membrane;GO:0005829//cytosol","GO:0005096//GTPase activator activity","GO:0007165//signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0008360//regulation of cell shape","K20637//Rho GTPase-activating protein 15","NP_060930.3//rho GTPase-activating protein 15 [Homo sapiens]","3//A2MP1"]
[4208,6446,0.01,0.05,2.32192809488736,0.355993867621483,"*",0.217844,"MEF2C","GO:0043231//intracellular membrane-bounded organelle;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0098794//postsynapse;GO:0043234//protein complex;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0001046//core promoter sequence-specific DNA binding;GO:0046982//protein heterodimerization activity;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003680//AT DNA binding;GO:0000983//transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding;GO:0046983//protein dimerization activity;GO:0003682//chromatin binding;GO:0035198//miRNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0033613//activating transcription factor binding","GO:0014902//myotube differentiation;GO:0071374//cellular response to parathyroid hormone stimulus;GO:0001568//blood vessel development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0050853//B cell receptor signaling pathway;GO:0000165//MAPK cascade;GO:0030182//neuron differentiation;GO:0007507//heart development;GO:0006351//transcription, DNA-templated;GO:0006915//apoptotic process;GO:0042100//B cell proliferation;GO:0030279//negative regulation of ossification;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:2001016//positive regulation of skeletal muscle cell differentiation;GO:2000727//positive regulation of cardiac muscle cell differentiation;GO:0045663//positive regulation of myoblast differentiation;GO:0001782//B cell homeostasis;GO:0009615//response to virus","K04454//MADS-box transcription enhancer factor 2C","NP_001180276.1//myocyte-specific enhancer factor 2C isoform 3 [Homo sapiens];NP_001180278.1//myocyte-specific enhancer factor 2C isoform 5 [Homo sapiens];NP_001180277.1//myocyte-specific enhancer factor 2C isoform 4 [Homo sapiens];EAW95965.1//MADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C), isoform CRA_d [Homo sapiens];EAW95967.1//MADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C), isoform CRA_f [Homo sapiens]","4;1//3;2//1"]
[286187,799,0.01,0.05,2.32192809488736,0.646253519902716,"*",0.499032,"PPP1R42","GO:0005815//microtubule organizing center;GO:0015630//microtubule cytoskeleton;GO:0002177//manchette;GO:0005813//centrosome;GO:0005737//cytoplasm","GO:0015631//tubulin binding;GO:0070840//dynein complex binding;GO:0003779//actin binding;GO:0008092//cytoskeletal protein binding","GO:0010921//regulation of phosphatase activity","K17579//protein phosphatase 1 regulatory subunit 42","NP_001013648.1//protein phosphatase 1 regulatory subunit 42 isoform 1 [Homo sapiens];NP_001335492.1//protein phosphatase 1 regulatory subunit 42 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[1180,3093,0.01,0.05,2.32192809488736,0.39288632224963,"*",0.249274,"CLCN1","GO:0005887//integral component of plasma membrane;GO:0042383//sarcolemma;GO:0034707//chloride channel complex;GO:0005886//plasma membrane","GO:0005247//voltage-gated chloride channel activity;GO:0042803//protein homodimerization activity","GO:0006936//muscle contraction;GO:0034220//ion transmembrane transport;GO:0019227//neuronal action potential propagation;GO:1902476//chloride transmembrane transport","K05010//chloride channel 1, skeletal muscle","XP_527935.3//PREDICTED: chloride channel protein 1 isoform X1 [Pan troglodytes]","2//1"]
[57047,1598,0.01,0.05,2.32192809488736,0.644946372815534,"*",0.499032,"PLSCR2","GO:0005634//nucleus;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0017128//phospholipid scramblase activity;GO:0005509//calcium ion binding","GO:0017121//phospholipid scrambling","NA","XP_011511315.2//PREDICTED: phospholipid scramblase 2 isoform X1 [Homo sapiens];EHH16696.1//hypothetical protein EGK_12025 [Macaca mulatta];NP_001186907.1//phospholipid scramblase 2 isoform 1 [Homo sapiens]","1//3;2//1"]
[254187,1726,0.01,0.05,2.32192809488736,0.644581318670656,"*",0.499032,"TSGA10IP","NA","NA","NA","K16772//protein FAM161A","NP_689975.2//testis-specific protein 10-interacting protein [Homo sapiens]","2//1"]
[285641,2983,0.01,0.05,2.32192809488736,0.644320818622696,"*",0.499032,"SLC36A3","GO:0005774//vacuolar membrane;GO:0016021//integral component of membrane","GO:0015193//L-proline transmembrane transporter activity;GO:0015187//glycine transmembrane transporter activity;GO:0015180//L-alanine transmembrane transporter activity;GO:0005280//hydrogen:amino acid symporter activity;GO:0015078//hydrogen ion transmembrane transporter activity","GO:0015816//glycine transport","K14209//solute carrier family 36 (proton-coupled amino acid transporter)","XP_010371987.1//PREDICTED: proton-coupled amino acid transporter 3 isoform X2 [Rhinopithecus roxellana];NP_001138489.1//proton-coupled amino acid transporter 3 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[254158,1547,0.01,0.05,2.32192809488736,0.644268743877798,"*",0.499032,"CXorf58","NA","NA","NA","NA","NP_689974.2//putative uncharacterized protein CXorf58 isoform 1 [Homo sapiens];NP_001163045.1//putative uncharacterized protein CXorf58 isoform 2 [Homo sapiens]","1//3;2//1"]
[1010,3709,0.02,0.1,2.32192809488736,0.35588464471262,"*",0.217844,"CDH12","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005509//calcium ion binding","GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules","K06804//cadherin 12, type 2, N-cadherin 2","XP_005386198.1//PREDICTED: cadherin-12 [Chinchilla lanigera];XP_020932697.1//cadherin-12 isoform X2 [Sus scrofa]","4;1//3"]
[388960,2990,0.01,0.05,2.32192809488736,0.392383018919984,"*",0.249274,"C2orf78","NA","NA","NA","K10431//microtubule-associated protein 4;K22016//mucin-3/17","NP_001073943.1//uncharacterized protein C2orf78 [Homo sapiens]","1//3"]
[160419,1705,0.01,0.05,2.32192809488736,0.643436691258374,"*",0.499032,"C12orf50","NA","NA","NA","NA","XP_016874376.1//PREDICTED: uncharacterized protein C12orf50 isoform X2 [Homo sapiens]","1//3"]
[91646,1617,0.01,0.05,2.32192809488736,0.643384759322034,"*",0.499032,"TDRD12","NA","NA","NA","K18409//ATP-dependent RNA helicase TDRD12 [EC:3.6.4.13]","XP_007994405.1//PREDICTED: putative ATP-dependent RNA helicase TDRD12 isoform X1 [Chlorocebus sabaeus]","1//3"]
[84824,2227,0.01,0.05,2.32192809488736,0.643073343659245,"*",0.499032,"FCRLA","GO:0016021//integral component of membrane;GO:0005737//cytoplasm","NA","GO:0030154//cell differentiation","K17273//Fc receptor-like protein 6","NP_001171802.1//Fc receptor-like A isoform 6 precursor [Homo sapiens];NP_001171799.1//Fc receptor-like A isoform 4 precursor [Homo sapiens];NP_116127.3//Fc receptor-like A isoform 2 precursor [Homo sapiens];NP_001171796.1//Fc receptor-like A isoform 3 precursor [Homo sapiens];NP_001171800.1//Fc receptor-like A isoform 7 precursor [Homo sapiens];NP_001171801.1//Fc receptor-like A isoform 5 precursor [Homo sapiens];NP_001171795.1//Fc receptor-like A isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[3624,6105,0.01,0.05,2.32192809488736,0.355811866666667,"*",0.217844,"INHBA","GO:0005615//extracellular space;GO:0043512//inhibin A complex;GO:0043509//activin A complex;GO:0005576//extracellular region;GO:0048471//perinuclear region of cytoplasm","GO:0008083//growth factor activity;GO:0005125//cytokine activity;GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity;GO:0034711//inhibin binding;GO:0005160//transforming growth factor beta receptor binding;GO:0005179//hormone activity;GO:0017046//peptide hormone binding;GO:0070699//type II activin receptor binding","GO:0045786//negative regulation of cell cycle;GO:0097191//extrinsic apoptotic signaling pathway;GO:0032270//positive regulation of cellular protein metabolic process;GO:0007166//cell surface receptor signaling pathway;GO:0008584//male gonad development;GO:0051799//negative regulation of hair follicle development;GO:0048468//cell development;GO:0008285//negative regulation of cell proliferation;GO:0060279//positive regulation of ovulation;GO:0042493//response to drug;GO:0030154//cell differentiation;GO:0043408//regulation of MAPK cascade;GO:0010628//positive regulation of gene expression;GO:0001541//ovarian follicle development;GO:0042326//negative regulation of phosphorylation;GO:0032924//activin receptor signaling pathway;GO:0046882//negative regulation of follicle-stimulating hormone secretion;GO:0071397//cellular response to cholesterol;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:2001241//positive regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0045648//positive regulation of erythrocyte differentiation;GO:0000082//G1/S transition of mitotic cell cycle;GO:0045077//negative regulation of interferon-gamma biosynthetic process;GO:0021773//striatal medium spiny neuron differentiation;GO:0007399//nervous system development;GO:0002244//hematopoietic progenitor cell differentiation;GO:0035987//endodermal cell differentiation;GO:0042541//hemoglobin biosynthetic process;GO:0007050//cell cycle arrest;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046881//positive regulation of follicle-stimulating hormone secretion;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0045650//negative regulation of macrophage differentiation;GO:0048333//mesodermal cell differentiation;GO:0060021//palate development;GO:0071372//cellular response to follicle-stimulating hormone stimulus;GO:0042476//odontogenesis;GO:0030308//negative regulation of cell growth;GO:0042701//progesterone secretion;GO:0061029//eyelid development in camera-type eye;GO:0007267//cell-cell signaling;GO:0030218//erythrocyte differentiation;GO:0060395//SMAD protein signal transduction;GO:0045578//negative regulation of B cell differentiation;GO:0006952//defense response;GO:0097154//GABAergic neuron differentiation;GO:0042981//regulation of apoptotic process;GO:0001942//hair follicle development;GO:0046880//regulation of follicle-stimulating hormone secretion","K04667//inhibin, beta","XP_016867663.1//PREDICTED: inhibin beta A chain isoform X1 [Homo sapiens]","3//A2MP1"]
[155184,1539,0.01,0.05,2.32192809488736,0.642244373831776,"*",0.499032,"SLC2A7","NA","NA","NA","K12201//MFS transporter, SP family, solute carrier family 2 (facilitated glucose/fructose transporter), member 7","XP_017358768.1//PREDICTED: solute carrier family 2, facilitated glucose transporter member 7 [Cebus capucinus imitator]","2//1"]
[10590,1492,0.01,0.05,2.32192809488736,0.642089179863069,"*",0.499032,"SCGN","GO:0030658//transport vesicle membrane;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005576//extracellular region;GO:0045202//synapse;GO:0005737//cytoplasm;GO:0043005//neuron projection","GO:0005509//calcium ion binding","GO:0051480//regulation of cytosolic calcium ion concentration","K14757//calbindin D28","NP_008929.2//secretagogin [Homo sapiens]","3//A2MP1"]
[53836,1521,0.01,0.05,2.32192809488736,0.641520776436504,"*",0.499032,"GPR87","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane","GO:0045028//G-protein coupled purinergic nucleotide receptor activity","GO:0007194//negative regulation of adenylate cyclase activity","K08389//G protein-coupled receptor 87","NP_076404.3//G-protein coupled receptor 87 [Homo sapiens]","3//A2MP1"]
[1158,1666,0.01,0.05,2.32192809488736,0.641469153295244,"*",0.499032,"CKM","NA","GO:0005524//ATP binding;GO:0004111//creatine kinase activity","GO:0046314//phosphocreatine biosynthetic process","K00933//creatine kinase [EC:2.7.3.2]","XP_010612927.2//PREDICTED: creatine kinase M-type [Fukomys damarensis]",4]
[27285,1536,0.01,0.05,2.32192809488736,0.641004918623352,"*",0.499032,"TEKT2","GO:0036126//sperm flagellum;GO:0005634//nucleus;GO:0005815//microtubule organizing center;GO:0005874//microtubule;GO:0005737//cytoplasm","NA","GO:0060294//cilium movement involved in cell motility;GO:0030317//flagellated sperm motility;GO:0060271//cilium assembly;GO:0036159//inner dynein arm assembly","K18629//tektin-2","NP_055281.2//tektin-2 [Homo sapiens]","2//1"]
[4100,1755,0.01,0.05,2.32192809488736,0.640129861720067,"*",0.499032,"MAGEA1","GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0042826//histone deacetylase binding","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045746//negative regulation of Notch signaling pathway;GO:0006351//transcription, DNA-templated","K12464//melanoma-associated antigen D1","NP_004979.3//melanoma-associated antigen 1 [Homo sapiens]",4]
[3860,1718,0.01,0.05,2.32192809488736,0.639975687861272,"*",0.499032,"KRT13","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0045111//intermediate filament cytoskeleton;GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0045095//keratin filament","GO:0005198//structural molecule activity","GO:0071300//cellular response to retinoic acid;GO:0009314//response to radiation;GO:0007010//cytoskeleton organization;GO:0043587//tongue morphogenesis;GO:0031424//keratinization;GO:0070268//cornification","K07604//type I keratin, acidic","NP_705694.2//keratin, type I cytoskeletal 13 isoform a [Homo sapiens];NP_002265.2//keratin, type I cytoskeletal 13 isoform b [Homo sapiens]","3//A2MP1;2//1"]
[5673,1601,0.01,0.05,2.32192809488736,0.639667562831006,"*",0.499032,"PSG5","NA","NA","NA","K06500//pregnancy specific beta-1-glycoprotein","XP_009230959.1//PREDICTED: pregnancy-specific beta-1-glycoprotein 5 isoform X4 [Pongo abelii]","1//3;3//A2MP1"]
[11250,1725,0.01,0.05,2.32192809488736,0.639616237503009,"*",0.499032,"GPR45","NA","NA","NA","K08409//G protein-coupled receptor 45","XP_515672.3//PREDICTED: probable G-protein coupled receptor 45 [Pan troglodytes]","3//A2MP1"]
[160762,1745,0.01,0.05,2.32192809488736,0.639513611552347,"*",0.499032,"CCDC63","GO:0005930//axoneme","NA","GO:0003341//cilium movement;GO:0007286//spermatid development;GO:0036158//outer dynein arm assembly","K10352//myosin heavy chain;K20282//GRIP and coiled-coil domain-containing protein 2;K06102//cingulin;K18626//trichohyalin;K16469//rootletin","AAH64580.1//CCDC63 protein, partial [Homo sapiens];NP_689804.1//coiled-coil domain-containing protein 63 isoform 1 [Homo sapiens]","1//3;2//1"]
[22914,1606,0.01,0.05,2.32192809488736,0.639462310925718,"*",0.499032,"KLRK1","GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0030246//carbohydrate binding;GO:0004872//receptor activity;GO:0032394//MHC class Ib receptor activity;GO:0042288//MHC class I protein binding;GO:0042803//protein homodimerization activity","GO:0007165//signal transduction;GO:0042267//natural killer cell mediated cytotoxicity;GO:0030154//cell differentiation;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0071222//cellular response to lipopolysaccharide;GO:0031295//T cell costimulation;GO:0002250//adaptive immune response;GO:0030101//natural killer cell activation;GO:2000502//negative regulation of natural killer cell chemotaxis;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0050830//defense response to Gram-positive bacterium;GO:0034260//negative regulation of GTPase activity;GO:0050776//regulation of immune response;GO:0032729//positive regulation of interferon-gamma production","K06728//killer cell lectin-like receptor subfamily K member 1","NP_031386.2//NKG2-D type II integral membrane protein [Homo sapiens]","3//A2MP1"]
[5920,779,0.54,2.68,2.3112016882943,6.95121570873786E-4,"Up",0.0001882494,"RARRES3","GO:0005829//cytosol;GO:0016021//integral component of membrane","GO:0016746//transferase activity, transferring acyl groups;GO:0004623//phospholipase A2 activity","GO:0036152//phosphatidylethanolamine acyl-chain remodeling;GO:0016042//lipid catabolic process;GO:0006644//phospholipid metabolic process;GO:0008285//negative regulation of cell proliferation","K16817//HRAS-like suppressor 3 [EC:3.1.1.32 3.1.1.4]","NP_004576.2//retinoic acid receptor responder protein 3 [Homo sapiens]",4]
[3133,2679,23.73,116.58,2.29653630111255,0,"Up",0,"HLA-E","NA","NA","NA","K06751//major histocompatibility complex, class I","XP_010366495.1//PREDICTED: LOW QUALITY PROTEIN: patr class I histocompatibility antigen, alpha chain E [Rhinopithecus roxellana]",5]
[129607,3014,0.11,0.53,2.2684888359259,0.00291156719136808,"*",0.000895306,"CMPK2","GO:0005739//mitochondrion;GO:0005737//cytoplasm","GO:0004798//thymidylate kinase activity;GO:0009041//uridylate kinase activity;GO:0005524//ATP binding;GO:0033862//UMP kinase activity;GO:0004550//nucleoside diphosphate kinase activity;GO:0004127//cytidylate kinase activity","GO:0006165//nucleoside diphosphate phosphorylation;GO:0006233//dTDP biosynthetic process;GO:0006235//dTTP biosynthetic process;GO:0071222//cellular response to lipopolysaccharide;GO:0006227//dUDP biosynthetic process;GO:0009142//nucleoside triphosphate biosynthetic process","K13809//UMP-CMP kinase 2, mitochondrial [EC:2.7.4.14]","NP_997198.2//UMP-CMP kinase 2, mitochondrial isoform 1 precursor [Homo sapiens];NP_001243407.1//UMP-CMP kinase 2, mitochondrial isoform 3 precursor [Homo sapiens];NP_001243406.1//UMP-CMP kinase 2, mitochondrial isoform 2 precursor [Homo sapiens]","1//3;3//A2MP1"]
[400629,1951,0.25,1.19,2.25096157353322,0.000272403588058204,"Up",{"v":6.7973e-05,"d":"6.80E-05"},"TEX19","NA","NA","NA","NA","XP_012511813.1//PREDICTED: testis-expressed protein 19.2-like [Propithecus coquereli]","3//A2MP1"]
[100288797,3114,0.43,2.03,2.23907116248308,{"v":4.04117270588235e-07,"d":"4.04E-07"},"Up",{"v":6.32208e-08,"d":"6.32E-08"},"TMEM239","GO:0016021//integral component of membrane","NA","NA","K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K15696//RING finger protein 113B;K17985//activating molecule in BECN1-regulated autophagy protein 1;K01064//wingless-type MMTV integration site family, member 9","BAC85208.1//unnamed protein product [Homo sapiens];NP_001305136.1//transmembrane protein 239 isoform 1 [Homo sapiens]","1//3;2//1"]
[440093,1071,0.26,1.22,2.23029761942179,0.0123170396116505,"*",0.0043681,"H3F3C","GO:0005719//nuclear euchromatin;GO:0000786//nucleosome","GO:0046982//protein heterodimerization activity;GO:0031492//nucleosomal DNA binding","GO:0006334//nucleosome assembly;GO:0030307//positive regulation of cell growth","K11253//histone H3","XP_007451114.1//PREDICTED: histone H3.3-like [Lipotes vexillifer]","2//1"]
[3569,1197,0.68,3.14,2.20715790764129,{"v":3.97976719394773e-06,"d":"3.98E-06"},"Up",{"v":7.245e-07,"d":"7.25E-07"},"IL6","GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0009897//external side of plasma membrane;GO:0005896//interleukin-6 receptor complex;GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0005138//interleukin-6 receptor binding;GO:0008083//growth factor activity;GO:0005125//cytokine activity","GO:0045079//negative regulation of chemokine biosynthetic process;GO:0002675//positive regulation of acute inflammatory response;GO:0045630//positive regulation of T-helper 2 cell differentiation;GO:0042102//positive regulation of T cell proliferation;GO:0071222//cellular response to lipopolysaccharide;GO:0071356//cellular response to tumor necrosis factor;GO:0042593//glucose homeostasis;GO:0045779//negative regulation of bone resorption;GO:0043065//positive regulation of apoptotic process;GO:0001781//neutrophil apoptotic process;GO:0071347//cellular response to interleukin-1;GO:0070102//interleukin-6-mediated signaling pathway;GO:0010574//regulation of vascular endothelial growth factor production;GO:0070091//glucagon secretion;GO:0070301//cellular response to hydrogen peroxide;GO:0009611//response to wounding;GO:0035729//cellular response to hepatocyte growth factor stimulus;GO:0050871//positive regulation of B cell activation;GO:2000660//negative regulation of interleukin-1-mediated signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0031018//endocrine pancreas development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0002384//hepatic immune response;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0072540//T-helper 17 cell lineage commitment;GO:0060445//branching involved in salivary gland morphogenesis;GO:0032755//positive regulation of interleukin-6 production;GO:0045727//positive regulation of translation;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0051024//positive regulation of immunoglobulin secretion;GO:0031175//neuron projection development;GO:0051384//response to glucocorticoid;GO:0071864//positive regulation of cell proliferation in bone marrow;GO:0060664//epithelial cell proliferation involved in salivary gland morphogenesis;GO:0042832//defense response to protozoan;GO:0032966//negative regulation of collagen biosynthetic process;GO:2000553//positive regulation of T-helper 2 cell cytokine production;GO:0046888//negative regulation of hormone secretion;GO:0051607//defense response to virus;GO:0006953//acute-phase response;GO:0002526//acute inflammatory response;GO:0007568//aging;GO:0006954//inflammatory response;GO:0046716//muscle cell cellular homeostasis;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0043410//positive regulation of MAPK cascade;GO:0006955//immune response;GO:0046849//bone remodeling;GO:0032722//positive regulation of chemokine production;GO:0050679//positive regulation of epithelial cell proliferation","K05405//interleukin 6","XP_011729449.1//PREDICTED: interleukin-6 isoform X3 [Macaca nemestrina];XP_017830595.1//PREDICTED: interleukin-6 isoform X1 [Callithrix jacchus]","1//3;4"]
[11067,2060,0.12,0.55,2.1963972128035,0.019868529492318,"*",0.0074479,"DEPP1","GO:0005739//mitochondrion;GO:0005737//cytoplasm","NA","NA","NA","NP_008952.1//protein DEPP [Homo sapiens]","3//A2MP1"]
[1154,2163,1.62,7.42,2.19542537373618,{"v":8.1548991907131e-24,"d":"8.15E-24"},"Up",{"v":3.07838e-25,"d":"3.08E-25"},"CISH","GO:0005829//cytosol;GO:0005622//intracellular;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0004860//protein kinase inhibitor activity","GO:0001558//regulation of cell growth;GO:0043687//post-translational protein modification;GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0016567//protein ubiquitination;GO:0046426//negative regulation of JAK-STAT cascade;GO:0035556//intracellular signal transduction;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0006469//negative regulation of protein kinase activity;GO:0019221//cytokine-mediated signaling pathway","K04701//cytokine inducible SH2-containing protein","NP_037456.5//cytokine-inducible SH2-containing protein isoform 1 [Homo sapiens];NP_659508.1//cytokine-inducible SH2-containing protein isoform 2 [Homo sapiens]","2//1;5"]
[84159,7226,0.37,1.67,2.1742509268451,{"v":3.04226467425968e-18,"d":"3.04E-18"},"Up",{"v":1.67216E-19,"d":"1.67E-19"},"ARID5B","GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0003677//DNA binding;GO:0003713//transcription coactivator activity;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0032452//histone demethylase activity;GO:0001227//transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding","GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0001822//kidney development;GO:0006355//regulation of transcription, DNA-templated;GO:0008584//male gonad development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0009791//post-embryonic development;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0060021//palate development;GO:0048468//cell development;GO:0060613//fat pad development;GO:0048705//skeletal system morphogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0001889//liver development;GO:0006351//transcription, DNA-templated;GO:0060612//adipose tissue development;GO:0010761//fibroblast migration;GO:0035264//multicellular organism growth;GO:0008585//female gonad development;GO:0048644//muscle organ morphogenesis;GO:1990830//cellular response to leukemia inhibitory factor;GO:0045444//fat cell differentiation;GO:0030325//adrenal gland development;GO:0060325//face morphogenesis","K07874//Ras-related protein Rab-1A;K00844//hexokinase [EC:2.7.1.1];K19195//AT-rich interactive domain-containing protein 4B","NP_115575.1//AT-rich interactive domain-containing protein 5B isoform 1 [Homo sapiens];NP_001231567.1//AT-rich interactive domain-containing protein 5B isoform 2 [Homo sapiens]","1//3;2//1"]
[23584,1299,0.06,0.27,2.16992500144231,0.356394925850061,"*",0.217844,"VSIG2","GO:0016020//membrane;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane","NA","NA","K06791//immunoglobulin superfamily, member 11","XP_010382927.1//PREDICTED: V-set and immunoglobulin domain-containing protein 2 [Rhinopithecus roxellana]","4;1//3"]
[285195,3647,0.02,0.09,2.16992500144231,0.356321938971943,"*",0.217844,"SLC9A9","GO:0031902//late endosome membrane;GO:0016021//integral component of membrane;GO:0055037//recycling endosome;GO:0005886//plasma membrane","GO:0015386//potassium:proton antiporter activity;GO:0015385//sodium:proton antiporter activity","GO:0098719//sodium ion import across plasma membrane;GO:0006885//regulation of pH;GO:0051453//regulation of intracellular pH;GO:0071805//potassium ion transmembrane transport;GO:0006811//ion transport","K14725//solute carrier family 9 (sodium/hydrogen exchanger), member 9","NP_775924.1//sodium/hydrogen exchanger 9 [Homo sapiens]","3//A2MP1"]
[339768,3631,0.02,0.09,2.16992500144231,0.227016259764598,"*",0.1243658,"ESPNL","GO:0032426//stereocilium tip;GO:0005737//cytoplasm","GO:0051015//actin filament binding","GO:0007605//sensory perception of sound;GO:0051017//actin filament bundle assembly","K15503//serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B;K19721//collagen, type V/XI/XXIV/XXVII, alpha;K10466//kelch-like protein 30;K14211//elastin;K19720//collagen, type III, alpha","NP_919288.2//espin-like protein isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[645426,1325,0.48,2.16,2.16992500144231,{"v":4.01936662160601e-05,"d":"4.02E-05"},"Up",{"v":8.71106e-06,"d":"8.71E-06"},"TMEM191C","GO:0016021//integral component of membrane","NA","NA","K06236//collagen, type I, alpha","NP_001193981.1//transmembrane protein 191C [Homo sapiens]","1//3"]
[146183,2718,0.02,0.09,2.16992500144231,0.530230126986946,"*",0.37379,"OTOA","GO:0009986//cell surface;GO:0016324//apical plasma membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0031225//anchored component of membrane;GO:0005578//proteinaceous extracellular matrix","NA","GO:0007160//cell-matrix adhesion;GO:0006501//C-terminal protein lipidation;GO:0019226//transmission of nerve impulse;GO:0007605//sensory perception of sound","K20733//mesothelin","NP_733764.1//otoancorin isoform 2 [Homo sapiens];NP_001155155.1//otoancorin isoform 3 [Homo sapiens];NP_653273.3//otoancorin isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1;2//1"]
[3090,3071,0.13,0.58,2.15754127698648,0.00182144384680851,"*",0.00053592,"HIC1","GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0000785//chromatin","GO:0046872//metal ion binding;GO:0042826//histone deacetylase binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0001227//transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0006355//regulation of transcription, DNA-templated;GO:0030178//negative regulation of Wnt signaling pathway;GO:0007275//multicellular organism development;GO:0016055//Wnt signaling pathway;GO:0006351//transcription, DNA-templated;GO:0043517//positive regulation of DNA damage response, signal transduction by p53 class mediator","K09228//KRAB domain-containing zinc finger protein","NP_001091672.1//hypermethylated in cancer 1 protein isoform 2 [Homo sapiens];XP_014973701.1//PREDICTED: hypermethylated in cancer 1 protein isoform X1 [Macaca mulatta]","1//3;3//A2MP1"]
[10420,2973,0.11,0.49,2.15527822547791,7.61784294227188E-3,"*",0.0025609,"TESK2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0005737//cytoplasm","GO:0004713//protein tyrosine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0046872//metal ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0004871//signal transducer activity","GO:0030036//actin cytoskeleton organization;GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction;GO:0007283//spermatogenesis;GO:0048041//focal adhesion assembly","K08842//testis-specific kinase 2 [EC:2.7.12.1]","NP_009101.2//dual specificity testis-specific protein kinase 2 isoform 1 [Homo sapiens]","1//3;2//1"]
[283710,1044,0.16,0.71,2.14974711950468,0.0842359918412348,"*",0.0382632,"LOC283710","NA","NA","NA","NA","NP_001230467.1//uncharacterized protein LOC283710 [Homo sapiens]","2//1"]
[1907,1168,0.71,3.15,2.1494608988826,{"v":2.50259711103228e-06,"d":"2.50E-06"},"Up",{"v":4.41644e-07,"d":"4.42E-07"},"EDN2","GO:0005615//extracellular space;GO:0005622//intracellular;GO:0005576//extracellular region","GO:0031708//endothelin B receptor binding;GO:0005179//hormone activity","GO:0001659//temperature homeostasis;GO:0019229//regulation of vasoconstriction;GO:0042310//vasoconstriction;GO:0007166//cell surface receptor signaling pathway;GO:0097009//energy homeostasis;GO:0014826//vein smooth muscle contraction;GO:0048016//inositol phosphate-mediated signaling;GO:0048246//macrophage chemotaxis;GO:0003058//hormonal regulation of the force of heart contraction;GO:0001516//prostaglandin biosynthetic process;GO:0060585//positive regulation of prostaglandin-endoperoxide synthase activity;GO:0010460//positive regulation of heart rate;GO:0030593//neutrophil chemotaxis;GO:0003100//regulation of systemic arterial blood pressure by endothelin;GO:0042116//macrophage activation;GO:0019722//calcium-mediated signaling;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0045987//positive regulation of smooth muscle contraction;GO:0003099//positive regulation of the force of heart contraction by chemical signal;GO:0014824//artery smooth muscle contraction;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0048286//lung alveolus development;GO:0019221//cytokine-mediated signaling pathway;GO:0008284//positive regulation of cell proliferation","K16367//endothelin-2","XP_524683.3//PREDICTED: endothelin-2 isoform X1 [Pan troglodytes]","4;1//3"]
[286256,694,0.36,1.58,2.13385574673479,0.0316458693782465,"*",0.01258584,"LCN12","GO:0005576//extracellular region","GO:0001972//retinoic acid binding;GO:0005215//transporter activity","GO:0015909//long-chain fatty acid transport;GO:0006629//lipid metabolic process","K21129//lipocalin 2;K03999//complement component 8 subunit gamma;K11454//chromobox protein 7","NP_848631.2//epididymal-specific lipocalin-12 precursor [Homo sapiens]","3//A2MP1"]
[375607,2953,0.03,0.13,2.11547721741994,0.22704220448,"*",0.1243658,"NAT16","NA","NA","NA","K10798//poly [ADP-ribose] polymerase [EC:2.4.2.30];K03129//transcription initiation factor TFIID subunit 4;K14456//2-acylglycerol O-acyltransferase 3 [EC:2.3.1.20 2.3.1.22]","EAW50202.1//FLJ39237 protein [Homo sapiens]","2//1"]
[130940,1226,0.03,0.13,2.11547721741994,0.355739118380699,"*",0.217844,"CCDC148","NA","NA","NA","K12875//apoptotic chromatin condensation inducer in the nucleus","XP_009441804.2//PREDICTED: coiled-coil domain-containing protein 148 isoform X6 [Pan troglodytes];AAM49716.1//unknown [Homo sapiens];NP_620158.3//coiled-coil domain-containing protein 148 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[100128908,2590,0.03,0.13,2.11547721741994,0.355593711015737,"*",0.217844,"LMLN2","NA","NA","NA","K13539//leishmanolysin-like peptidase [EC:3.4.24.-]","NP_001341569.1//leishmanolysin like peptidase 2 precursor [Homo sapiens]","1//3"]
[91319,3115,0.07,0.3,2.09953567355091,0.255285180434064,"*",0.1450622,"DERL3","GO:0030176//integral component of endoplasmic reticulum membrane;GO:0048500//signal recognition particle;GO:0005785//signal recognition particle receptor complex","NA","GO:0018279//protein N-linked glycosylation via asparagine;GO:0030433//ubiquitin-dependent ERAD pathway;GO:1904153//negative regulation of retrograde protein transport, ER to cytosol;GO:0030968//endoplasmic reticulum unfolded protein response","K13989//Derlin-2/3","XP_019292971.1//PREDICTED: derlin-3 isoform X2 [Panthera pardus];XP_012309533.1//derlin-3 isoform X1 [Aotus nancymaae];XP_015102581.1//PREDICTED: derlin-3 isoform X5 [Vicugna pacos]","1//3;3//A2MP1;2//1"]
[80833,2266,0.07,0.3,2.09953567355091,0.131606716804058,"*",0.064963,"APOL3","GO:0016020//membrane;GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0005319//lipid transporter activity;GO:0008289//lipid binding;GO:0004871//signal transducer activity","GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0006869//lipid transport;GO:0042157//lipoprotein metabolic process;GO:0006954//inflammatory response","K14480//apolipoprotein L","NP_055164.1//apolipoprotein L3 isoform 2 [Homo sapiens];NP_663615.1//apolipoprotein L3 isoform 1 [Homo sapiens]","1//3;2//1"]
[84519,1886,0.04,0.17,2.08746284125034,0.355666399836468,"*",0.217844,"ACRBP","GO:0005634//nucleus;GO:0005576//extracellular region;GO:0001669//acrosomal vesicle;GO:0002080//acrosomal membrane","NA","GO:0048240//sperm capacitation","K04574//neurofilament heavy polypeptide;K16751//C2 domain-containing protein 3","NP_115878.2//acrosin-binding protein precursor [Homo sapiens]","2//1"]
[4665,2690,10.56,44.5,2.07519550138267,{"v":1.14878922666667E-167,"d":"1.15E-167"},"Up",{"v":3.02048E-170,"d":"3.02E-170"},"NAB2","GO:0005634//nucleus","GO:0003714//transcription corepressor activity;GO:0042802//identical protein binding;GO:0008134//transcription factor binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0007399//nervous system development;GO:0042552//myelination;GO:0001958//endochondral ossification;GO:0006351//transcription, DNA-templated;GO:0045682//regulation of epidermis development;GO:0016480//negative regulation of transcription from RNA polymerase III promoter;GO:0014037//Schwann cell differentiation;GO:0008283//cell proliferation;GO:1902949//positive regulation of tau-protein kinase activity","NA","XP_020018846.1//NGFI-A-binding protein 2 [Castor canadensis]","1//3;3//A2MP1"]
[2819,3083,0.05,0.21,2.0703893278914,0.131623409690512,"*",0.064963,"GPD1","GO:0070062//extracellular exosome;GO:0009331//glycerol-3-phosphate dehydrogenase complex;GO:0005829//cytosol;GO:0005739//mitochondrion","GO:0051287//NAD binding;GO:0042803//protein homodimerization activity;GO:0004368//glycerol-3-phosphate dehydrogenase activity;GO:0004367//glycerol-3-phosphate dehydrogenase [NAD+] activity","GO:0006127//glycerophosphate shuttle;GO:0046486//glycerolipid metabolic process;GO:0046168//glycerol-3-phosphate catabolic process;GO:0006094//gluconeogenesis;GO:0071356//cellular response to tumor necrosis factor;GO:0071320//cellular response to cAMP;GO:0006654//phosphatidic acid biosynthetic process;GO:0045821//positive regulation of glycolytic process","K00006//glycerol-3-phosphate dehydrogenase (NAD+) [EC:1.1.1.8]","XP_007179402.1//PREDICTED: glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic [Balaenoptera acutorostrata scammoni]","1//3;3//A2MP1"]
[3274,3095,0.12,0.5,2.05889368905357,0.0121094229026549,"*",0.0042831,"HRH2","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004969//histamine receptor activity","GO:0008542//visual learning;GO:0001697//histamine-induced gastric acid secretion;GO:0048732//gland development;GO:0003382//epithelial cell morphogenesis;GO:0001698//gastrin-induced gastric acid secretion;GO:0048565//digestive tract development;GO:0007613//memory;GO:0045907//positive regulation of vasoconstriction;GO:1901998//toxin transport;GO:0006955//immune response;GO:0001696//gastric acid secretion;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0048167//regulation of synaptic plasticity","K04150//histamine receptor H2","NP_001124527.1//histamine H2 receptor isoform 1 [Homo sapiens];XP_018884165.1//PREDICTED: histamine H2 receptor isoform X3 [Gorilla gorilla gorilla]","1//3;2//1"]
[84875,3548,0.2,0.83,2.05311133645956,1.04737679219724E-4,"Up",{"v":2.4201e-05,"d":"2.42E-05"},"PARP10","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0070530//K63-linked polyubiquitin modification-dependent protein binding;GO:0003950//NAD+ ADP-ribosyltransferase activity","GO:0010847//regulation of chromatin assembly;GO:0033159//negative regulation of protein import into nucleus, translocation;GO:0034356//NAD biosynthesis via nicotinamide riboside salvage pathway;GO:0070212//protein poly-ADP-ribosylation;GO:0010629//negative regulation of gene expression;GO:0048147//negative regulation of fibroblast proliferation;GO:0045071//negative regulation of viral genome replication;GO:0070213//protein auto-ADP-ribosylation;GO:1900045//negative regulation of protein K63-linked ubiquitination;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0006471//protein ADP-ribosylation","K15261//poly [ADP-ribose] polymerase 10/14/15 [EC:2.4.2.30]","NP_001304824.1//poly [ADP-ribose] polymerase 10 isoform 2 [Homo sapiens]","4;1//3"]
[183,2587,0.09,0.37,2.03952836418664,0.049771844983723,"*",0.0210566,"AGT","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0072562//blood microparticle;GO:0005829//cytosol;GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0031702//type 1 angiotensin receptor binding;GO:0008083//growth factor activity;GO:0031703//type 2 angiotensin receptor binding;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0048018//receptor ligand activity;GO:0005179//hormone activity","GO:0032930//positive regulation of superoxide anion generation;GO:1905010//positive regulation of L-lysine import across plasma membrane;GO:0045777//positive regulation of blood pressure;GO:0071260//cellular response to mechanical stimulus;GO:1905589//positive regulation of L-arginine import across plasma membrane;GO:0003331//positive regulation of extracellular matrix constituent secretion;GO:0007166//cell surface receptor signaling pathway;GO:0070371//ERK1 and ERK2 cascade;GO:1904707//positive regulation of vascular smooth muscle cell proliferation;GO:0014873//response to muscle activity involved in regulation of muscle adaptation;GO:1904754//positive regulation of vascular associated smooth muscle cell migration;GO:0007565//female pregnancy;GO:0035411//catenin import into nucleus;GO:0048144//fibroblast proliferation;GO:0048146//positive regulation of fibroblast proliferation;GO:0070471//uterine smooth muscle contraction;GO:0003051//angiotensin-mediated drinking behavior;GO:0007202//activation of phospholipase C activity;GO:0014824//artery smooth muscle contraction;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0051403//stress-activated MAPK cascade;GO:0002018//renin-angiotensin regulation of aldosterone production;GO:2001275//positive regulation of glucose import in response to insulin stimulus;GO:0050663//cytokine secretion;GO:0034104//negative regulation of tissue remodeling;GO:0051924//regulation of calcium ion transport;GO:0038166//angiotensin-activated signaling pathway;GO:0002003//angiotensin maturation;GO:0006883//cellular sodium ion homeostasis;GO:0010666//positive regulation of cardiac muscle cell apoptotic process;GO:0042311//vasodilation;GO:0048659//smooth muscle cell proliferation;GO:0051969//regulation of transmission of nerve impulse;GO:0030308//negative regulation of cell growth;GO:0007186//G-protein coupled receptor signaling pathway;GO:0016525//negative regulation of angiogenesis;GO:0002027//regulation of heart rate;GO:0007568//aging;GO:0010613//positive regulation of cardiac muscle hypertrophy;GO:0061049//cell growth involved in cardiac muscle cell development;GO:0035815//positive regulation of renal sodium excretion;GO:0003081//regulation of systemic arterial blood pressure by renin-angiotensin;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0014061//regulation of norepinephrine secretion","K09821//angiotensinogen","BAD93006.1//angiotensinogen precursor variant, partial [Homo sapiens]","3//A2MP1"]
[8542,2884,4.09,16.57,2.0184008542797,{"v":1.01858211e-63,"d":"1.02E-63"},"Up",{"v":1.02024e-65,"d":"1.02E-65"},"APOL1","NA","NA","NA","K14480//apolipoprotein L","NP_663318.1//apolipoprotein L1 isoform b precursor [Homo sapiens];AAI42721.1//APOL1 protein, partial [Homo sapiens]","1//3;3//A2MP1;2//1"]
[144347,2160,0.01,0.04,2,0.65593163564552,"*",0.499032,"RFLNA","GO:0032432//actin filament bundle","GO:0031005//filamin binding","GO:1900158//negative regulation of bone mineralization involved in bone maturation;GO:0061182//negative regulation of chondrocyte development;GO:0048705//skeletal system morphogenesis;GO:0061572//actin filament bundle organization","NA","Q6ZTI6.3//RecName: Full=Refilin-A; AltName: Full=Regulator of filamin protein A; Short=RefilinA",4]
[266629,2230,0.01,0.04,2,0.655877667270034,"*",0.499032,"SEC14L3","GO:0070062//extracellular exosome;GO:0005622//intracellular;GO:0016021//integral component of membrane","GO:0005215//transporter activity","NA","K21954//FYVE and coiled-coil domain-containing protein 1;K01019//galactosylceramide sulfotransferase [EC:2.8.2.11];K19625//retinaldehyde-binding protein 1;K17981//mitochondrial fission process protein 1","XP_002915610.1//PREDICTED: SEC14-like protein 3 [Ailuropoda melanoleuca]","1//3;4"]
[55784,4358,0.01,0.04,2,0.227135796322942,"*",0.1245166,"MCTP2","GO:0016020//membrane;GO:0005654//nucleoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0016021//integral component of membrane","GO:0005509//calcium ion binding","GO:0007275//multicellular organism development;GO:0019722//calcium-mediated signaling","K20045//intersectin","NP_001153115.1//multiple C2 and transmembrane domain-containing protein 2 isoform 2 [Homo sapiens];XP_003268576.2//PREDICTED: multiple C2 and transmembrane domain-containing protein 2 isoform X1 [Nomascus leucogenys];XP_011520075.1//PREDICTED: multiple C2 and transmembrane domain-containing protein 2 isoform X4 [Homo sapiens]","1//3;3//A2MP1"]
[84203,1972,0.01,0.04,2,0.655176885674365,"*",0.499032,"TXNDC2","GO:0005623//cell;GO:0005737//cytoplasm","GO:0047134//protein-disulfide reductase activity;GO:0015035//protein disulfide oxidoreductase activity;GO:0016671//oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor;GO:0004791//thioredoxin-disulfide reductase activity","GO:0006662//glycerol ether metabolic process;GO:0030154//cell differentiation;GO:0007275//multicellular organism development;GO:0034599//cellular response to oxidative stress;GO:0007283//spermatogenesis;GO:0045454//cell redox homeostasis","K03006//DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]","NP_001091999.1//thioredoxin domain-containing protein 2 isoform 2 [Homo sapiens]","1//3;5"]
[10990,1972,0.01,0.04,2,0.654746379301848,"*",0.499032,"LILRB5","GO:0016021//integral component of membrane","GO:0004888//transmembrane signaling receptor activity","GO:0006952//defense response;GO:0007166//cell surface receptor signaling pathway;GO:0002250//adaptive immune response","K06512//leukocyte immunoglobulin-like receptor","NP_001074911.1//leukocyte immunoglobulin-like receptor subfamily B member 5 isoform 1 precursor [Homo sapiens];NP_001074912.1//leukocyte immunoglobulin-like receptor subfamily B member 5 isoform 3 precursor [Homo sapiens];NP_001291386.1//leukocyte immunoglobulin-like receptor subfamily B member 5 isoform 4 precursor [Homo sapiens];NP_006831.1//leukocyte immunoglobulin-like receptor subfamily B member 5 isoform 2 precursor [Homo sapiens]","1//3;4;2//1"]
[120935,1972,0.01,0.04,2,0.654423870618176,"*",0.499032,"CCDC38","GO:0005813//centrosome;GO:0005737//cytoplasm","NA","NA","K17455//fascin 1/2;K01468//imidazolonepropionase [EC:3.5.2.7];K20478//golgin subfamily B member 1;K04345//protein kinase A [EC:2.7.11.11]","NP_872302.2//coiled-coil domain-containing protein 38 [Homo sapiens]","2//1"]
[2912,3364,0.01,0.04,2,0.654316438315686,"*",0.499032,"GRM2","GO:0030425//dendrite;GO:0030424//axon;GO:0005622//intracellular;GO:0030054//cell junction;GO:0043005//neuron projection;GO:0005887//integral component of plasma membrane;GO:0042734//presynaptic membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0008066//glutamate receptor activity;GO:0005246//calcium channel regulator activity;GO:0001641//group II metabotropic glutamate receptor activity;GO:0004930//G-protein coupled receptor activity","GO:0051966//regulation of synaptic transmission, glutamatergic;GO:0007194//negative regulation of adenylate cyclase activity;GO:0007216//G-protein coupled glutamate receptor signaling pathway;GO:0007268//chemical synaptic transmission;GO:0014047//glutamate secretion","K04605//metabotropic glutamate receptor 2/3","XP_017810909.1//metabotropic glutamate receptor 2 isoform X1 [Papio anubis];BAD92401.1//glutamate receptor homolog, partial [Homo sapiens];XP_016796687.1//PREDICTED: metabotropic glutamate receptor 2 isoform X2 [Pan troglodytes]","1//3;4"]
[4110,1892,0.01,0.04,2,0.653994352941176,"*",0.499032,"MAGEA11","GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0005829//cytosol","NA","NA","K12464//melanoma-associated antigen D1","NP_001011544.1//melanoma-associated antigen 11 isoform b [Homo sapiens];NP_005357.2//melanoma-associated antigen 11 isoform a [Homo sapiens]","1//3;4"]
[1041,2583,0.03,0.12,2,0.356285456742091,"*",0.217844,"CDSN","GO:0070062//extracellular exosome;GO:0001533//cornified envelope;GO:0005911//cell-cell junction;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0030057//desmosome","GO:0042803//protein homodimerization activity","GO:0043589//skin morphogenesis;GO:0030216//keratinocyte differentiation;GO:0003336//corneocyte desquamation;GO:0070268//cornification;GO:0098609//cell-cell adhesion;GO:0007155//cell adhesion;GO:0008544//epidermis development;GO:1905716//negative regulation of cornification","K22022//mucin-21;K22020//mucin-19;K12374//arylsulfatase D/F/H [EC:3.1.6.-]","NP_001255.3//corneodesmosin precursor [Homo sapiens]",4]
[3882,2005,0.01,0.04,2,0.65377980546215,"*",0.499032,"KRT32","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0005882//intermediate filament","GO:0005198//structural molecule activity","GO:0008544//epidermis development;GO:0031424//keratinization;GO:0070268//cornification","K07604//type I keratin, acidic","NP_002269.3//keratin, type I cuticular Ha2 [Homo sapiens]","3//A2MP1"]
[286204,5645,0.01,0.04,2,0.227058010091324,"*",0.1245166,"CRB2","GO:0070062//extracellular exosome;GO:0045121//membrane raft;GO:0016324//apical plasma membrane;GO:0043234//protein complex;GO:0016021//integral component of membrane","GO:0005509//calcium ion binding;GO:0019899//enzyme binding","GO:0010951//negative regulation of endopeptidase activity;GO:0010470//regulation of gastrulation;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0030513//positive regulation of BMP signaling pathway;GO:0014028//notochord formation;GO:0001707//mesoderm formation;GO:0072358//cardiovascular system development;GO:0055111//ingression involved in gastrulation with mouth forming second;GO:0001756//somitogenesis;GO:0045199//maintenance of epithelial cell apical/basal polarity","K16681//protein crumbs","NP_775960.4//protein crumbs homolog 2 precursor [Homo sapiens]",6]
[24141,1927,0.01,0.04,2,0.653190525073746,"*",0.499032,"LAMP5","GO:0010008//endosome membrane;GO:0030054//cell junction;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0032584//growth cone membrane;GO:0055038//recycling endosome membrane;GO:0031901//early endosome membrane;GO:0032590//dendrite membrane;GO:0030672//synaptic vesicle membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0030659//cytoplasmic vesicle membrane","NA","NA","K09228//KRAB domain-containing zinc finger protein;K06528//lysosomal-associated membrane protein 1/2","NP_036393.1//lysosome-associated membrane glycoprotein 5 isoform 1 precursor [Homo sapiens];NP_001186826.1//lysosome-associated membrane glycoprotein 5 isoform 2 precursor [Homo sapiens]","1//3;3//A2MP1"]
[5008,1876,0.01,0.04,2,0.652923021377672,"*",0.499032,"OSM","GO:0005615//extracellular space;GO:0005622//intracellular;GO:0005576//extracellular region","GO:0008083//growth factor activity;GO:0005125//cytokine activity;GO:0005147//oncostatin-M receptor binding","GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0002675//positive regulation of acute inflammatory response;GO:0040008//regulation of growth;GO:0051781//positive regulation of cell division;GO:0045835//negative regulation of meiotic nuclear division;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0008283//cell proliferation;GO:0008285//negative regulation of cell proliferation;GO:0007260//tyrosine phosphorylation of STAT protein;GO:0038165//oncostatin-M-mediated signaling pathway;GO:0046888//negative regulation of hormone secretion;GO:0009408//response to heat;GO:2001235//positive regulation of apoptotic signaling pathway;GO:0048266//behavioral response to pain;GO:0007275//multicellular organism development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006955//immune response;GO:0043410//positive regulation of MAPK cascade;GO:0007422//peripheral nervous system development;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0008284//positive regulation of cell proliferation","K05418//oncostatin M","NP_065391.1//oncostatin-M isoform 1 preproprotein [Homo sapiens]","1//3;5"]
[7471,2284,0.01,0.04,2,0.652816081238228,"*",0.499032,"WNT1","GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0009986//cell surface;GO:0030666//endocytic vesicle membrane;GO:0005737//cytoplasm;GO:0005578//proteinaceous extracellular matrix","GO:0019904//protein domain specific binding;GO:0005125//cytokine activity;GO:0005102//receptor binding;GO:0044212//transcription regulatory region DNA binding;GO:0016015//morphogen activity;GO:0005109//frizzled binding","GO:0031100//animal organ regeneration;GO:0045747//positive regulation of Notch signaling pathway;GO:0022004//midbrain-hindbrain boundary maturation during brain development;GO:0021527//spinal cord association neuron differentiation;GO:0043568//positive regulation of insulin-like growth factor receptor signaling pathway;GO:0022408//negative regulation of cell-cell adhesion;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0042472//inner ear morphogenesis;GO:1990403//embryonic brain development;GO:0009611//response to wounding;GO:0000578//embryonic axis specification;GO:1903204//negative regulation of oxidative stress-induced neuron death;GO:0048146//positive regulation of fibroblast proliferation;GO:0045599//negative regulation of fat cell differentiation;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0042770//signal transduction in response to DNA damage;GO:0010592//positive regulation of lamellipodium assembly;GO:0007275//multicellular organism development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0016055//Wnt signaling pathway;GO:2000059//negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0030514//negative regulation of BMP signaling pathway;GO:1904886//beta-catenin destruction complex disassembly;GO:0033278//cell proliferation in midbrain;GO:0033077//T cell differentiation in thymus;GO:0021797//forebrain anterior/posterior pattern specification;GO:0071425//hematopoietic stem cell proliferation;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0044336//canonical Wnt signaling pathway involved in negative regulation of apoptotic process;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:1904954//canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation;GO:0061184//positive regulation of dermatome development;GO:0001934//positive regulation of protein phosphorylation;GO:0060061//Spemann organizer formation;GO:0021588//cerebellum formation;GO:0045165//cell fate commitment;GO:0060348//bone development;GO:0030182//neuron differentiation;GO:0007520//myoblast fusion;GO:0021536//diencephalon development;GO:0090344//negative regulation of cell aging;GO:0048664//neuron fate determination;GO:0030579//ubiquitin-dependent SMAD protein catabolic process;GO:0010812//negative regulation of cell-substrate adhesion;GO:0021551//central nervous system morphogenesis;GO:0036520//astrocyte-dopaminergic neuron signaling","K03209//wingless-type MMTV integration site family, member 1","NP_005421.1//proto-oncogene Wnt-1 precursor [Homo sapiens]","3//A2MP1"]
[9547,1989,0.01,0.04,2,0.652762624303963,"*",0.499032,"CXCL14","NA","NA","NA","K10033//C-X-C motif chemokine 14","EAW62211.1//hCG39697, isoform CRA_a, partial [Homo sapiens]",4]
[4168,3867,0.01,0.04,2,0.394951683792898,"*",0.249274,"MCF2","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005856//cytoskeleton;GO:0005829//cytosol","GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005089//Rho guanyl-nucleotide exchange factor activity","GO:0043065//positive regulation of apoptotic process;GO:1990830//cellular response to leukemia inhibitory factor;GO:0016358//dendrite development;GO:0035023//regulation of Rho protein signal transduction;GO:0035556//intracellular signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction","K20685//guanine nucleotide exchange factor MCF2","XP_005262470.1//PREDICTED: proto-oncogene DBL isoform X2 [Homo sapiens];NP_001165348.1//proto-oncogene DBL isoform d [Homo sapiens];NP_005360.3//proto-oncogene DBL isoform b [Homo sapiens];NP_001165350.1//proto-oncogene DBL isoform f [Homo sapiens];NP_001165349.1//proto-oncogene DBL isoform e [Homo sapiens]","4;1//3"]
[9699,7097,0.01,0.04,2,0.226980277119708,"*",0.1245166,"RIMS2","GO:0070062//extracellular exosome;GO:0048786//presynaptic active zone;GO:0042734//presynaptic membrane;GO:0005622//intracellular;GO:0030054//cell junction","GO:0046872//metal ion binding;GO:0044325//ion channel binding;GO:0017137//Rab GTPase binding","GO:2000300//regulation of synaptic vesicle exocytosis;GO:0048791//calcium ion-regulated exocytosis of neurotransmitter;GO:0010628//positive regulation of gene expression;GO:0030073//insulin secretion;GO:0017156//calcium ion regulated exocytosis;GO:0097151//positive regulation of inhibitory postsynaptic potential;GO:2000463//positive regulation of excitatory postsynaptic potential;GO:0019933//cAMP-mediated signaling;GO:0006886//intracellular protein transport;GO:0017157//regulation of exocytosis;GO:1903861//positive regulation of dendrite extension;GO:0061669//spontaneous neurotransmitter secretion;GO:0042391//regulation of membrane potential","K15297//regulating synaptic membrane exocytosis protein 2","NP_001335432.1//regulating synaptic membrane exocytosis protein 2 isoform x [Homo sapiens];NP_001335417.1//regulating synaptic membrane exocytosis protein 2 isoform i [Homo sapiens];NP_001335436.1//regulating synaptic membrane exocytosis protein 2 isoform bb [Homo sapiens];NP_001335434.1//regulating synaptic membrane exocytosis protein 2 isoform z [Homo sapiens];NP_001335433.1//regulating synaptic membrane exocytosis protein 2 isoform y [Homo sapiens];NP_001335415.1//regulating synaptic membrane exocytosis protein 2 isoform g [Homo sapiens];NP_001335416.1//regulating synaptic membrane exocytosis protein 2 isoform h [Homo sapiens];NP_001335427.1//regulating synaptic membrane exocytosis protein 2 isoform s [Homo sapiens];NP_001335429.1//regulating synaptic membrane exocytosis protein 2 isoform u [Homo sapiens];NP_001335422.1//regulating synaptic membrane exocytosis protein 2 isoform n [Homo sapiens];XP_005613300.1//PREDICTED: regulating synaptic membrane exocytosis protein 2 isoform X6 [Equus caballus];NP_001335431.1//regulating synaptic membrane exocytosis protein 2 isoform w [Homo sapiens];NP_001335424.1//regulating synaptic membrane exocytosis protein 2 isoform p [Homo sapiens];NP_001335414.1//regulating synaptic membrane exocytosis protein 2 isoform f [Homo sapiens];NP_001335421.1//regulating synaptic membrane exocytosis protein 2 isoform m [Homo sapiens];NP_055492.3//regulating synaptic membrane exocytosis protein 2 isoform b [Homo sapiens];NP_001335418.1//regulating synaptic membrane exocytosis protein 2 isoform j [Homo sapiens];NP_001269810.1//regulating synaptic membrane exocytosis protein 2 isoform c [Homo sapiens];NP_001335430.1//regulating synaptic membrane exocytosis protein 2 isoform v [Homo sapiens];NP_001335413.1//regulating synaptic membrane exocytosis protein 2 isoform e [Homo sapiens];NP_001093587.1//regulating synaptic membrane exocytosis protein 2 isoform a [Homo sapiens];NP_001335423.1//regulating synaptic membrane exocytosis protein 2 isoform o [Homo sapiens];NP_001335426.1//regulating synaptic membrane exocytosis protein 2 isoform r [Homo sapiens];NP_001335435.1//regulating synaptic membrane exocytosis protein 2 isoform aa [Homo sapiens];NP_001335420.1//regulating synaptic membrane exocytosis protein 2 isoform l [Homo sapiens];NP_001335437.1//regulating synaptic membrane exocytosis protein 2 isoform cc [Homo sapiens];NP_001335438.1//regulating synaptic membrane exocytosis protein 2 isoform dd [Homo sapiens];NP_001335428.1//regulating synaptic membrane exocytosis protein 2 isoform t [Homo sapiens];NP_001335425.1//regulating synaptic membrane exocytosis protein 2 isoform q [Homo sapiens];NP_001335419.1//regulating synaptic membrane exocytosis protein 2 isoform k [Homo sapiens]","4;1//3;2//1"]
[442247,1900,0.01,0.04,2,0.65206848,"*",0.499032,"RFPL4B","NA","GO:0046872//metal ion binding","NA","K12009//tripartite motif-containing protein 27 [EC:2.3.2.27];K10651//tripartite motif-containing protein 21 [EC:2.3.2.27]","NP_001013756.2//ret finger protein-like 4B [Homo sapiens]","2//1"]
[56606,1874,0.01,0.04,2,0.651429040451091,"*",0.499032,"SLC2A9","GO:0016021//integral component of membrane","NA","GO:0008643//carbohydrate transport","K08146//MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 9","XP_008991848.2//PREDICTED: solute carrier family 2, facilitated glucose transporter member 9 isoform X2 [Callithrix jacchus];XP_016806815.1//PREDICTED: solute carrier family 2, facilitated glucose transporter member 9 isoform X4 [Pan troglodytes]","1//3;2//1"]
[65997,1979,0.01,0.04,2,0.650366090234152,"*",0.499032,"RASL11B","GO:0016020//membrane","GO:0005525//GTP binding;GO:0005160//transforming growth factor beta receptor binding;GO:0003924//GTPase activity","GO:0007165//signal transduction;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway","K07853//Ras-like protein family member 11B","NP_076429.1//ras-like protein family member 11B [Homo sapiens]","2//1"]
[220441,1805,0.01,0.04,2,0.650047881268857,"*",0.499032,"RNF152","GO:0005765//lysosomal membrane;GO:0031301//integral component of organelle membrane;GO:0016021//integral component of membrane;GO:0005764//lysosome","GO:0031267//small GTPase binding;GO:0061630//ubiquitin protein ligase activity;GO:0046872//metal ion binding;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity","GO:0070534//protein K63-linked ubiquitination;GO:0070936//protein K48-linked ubiquitination;GO:0034198//cellular response to amino acid starvation;GO:0016567//protein ubiquitination;GO:0010508//positive regulation of autophagy;GO:1904262//negative regulation of TORC1 signaling;GO:0006915//apoptotic process;GO:0000209//protein polyubiquitination","K15705//E3 ubiquitin-protein ligase RNF152 [EC:2.3.2.27]","XP_020040697.1//E3 ubiquitin-protein ligase RNF152 [Castor canadensis]","2//1"]
[89866,4347,0.01,0.04,2,0.393974757692688,"*",0.249274,"SEC16B","GO:0043231//intracellular membrane-bounded organelle;GO:0005829//cytosol;GO:0005789//endoplasmic reticulum membrane;GO:0000139//Golgi membrane","NA","GO:0007031//peroxisome organization;GO:0048208//COPII vesicle coating;GO:0015031//protein transport;GO:0010628//positive regulation of gene expression;GO:0070863//positive regulation of protein exit from endoplasmic reticulum;GO:0016559//peroxisome fission;GO:0007029//endoplasmic reticulum organization","K20353//COPII coat assembly protein SEC16","NP_149118.2//protein transport protein Sec16B [Homo sapiens];AAH09106.1//SEC16B protein [Homo sapiens]","1//3;3//A2MP1"]
[10164,2145,0.01,0.04,2,0.648830959466059,"*",0.499032,"CHST4","GO:0031228//intrinsic component of Golgi membrane;GO:0016021//integral component of membrane;GO:0005802//trans-Golgi network;GO:0000139//Golgi membrane","GO:0008146//sulfotransferase activity;GO:0001517//N-acetylglucosamine 6-O-sulfotransferase activity","GO:0006790//sulfur compound metabolic process;GO:0006044//N-acetylglucosamine metabolic process;GO:0007267//cell-cell signaling;GO:0006477//protein sulfation;GO:0016266//O-glycan processing;GO:0006954//inflammatory response;GO:0007155//cell adhesion;GO:0018146//keratan sulfate biosynthetic process;GO:0006928//movement of cell or subcellular component;GO:0005975//carbohydrate metabolic process;GO:0006955//immune response","K04746//carbohydrate 6-sulfotransferase 4 [EC:2.8.2.-]","NP_005760.1//carbohydrate sulfotransferase 4 [Homo sapiens]","1//3;2//1"]
[10841,1917,0.01,0.04,2,0.648778153170017,"*",0.499032,"FTCD","GO:0070062//extracellular exosome;GO:0005783//endoplasmic reticulum;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005737//cytoplasm;GO:0000139//Golgi membrane;GO:0005814//centriole;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0030868//smooth endoplasmic reticulum membrane","GO:0030412//formimidoyltetrahydrofolate cyclodeaminase activity;GO:0005542//folic acid binding;GO:0030409//glutamate formimidoyltransferase activity;GO:0008017//microtubule binding;GO:0030407//formimidoyltransferase activity","GO:0019557//histidine catabolic process to glutamate and formate;GO:0006760//folic acid-containing compound metabolic process;GO:0007010//cytoskeleton organization;GO:0035999//tetrahydrofolate interconversion;GO:0006548//histidine catabolic process;GO:0019556//histidine catabolic process to glutamate and formamide","K13990//glutamate formiminotransferase / formiminotetrahydrofolate cyclodeaminase [EC:2.1.2.5 4.3.1.4]","EAX09312.1//formiminotransferase cyclodeaminase, isoform CRA_d, partial [Homo sapiens];EAX09308.1//formiminotransferase cyclodeaminase, isoform CRA_a [Homo sapiens]","1//3;2//1"]
[255877,3544,0.01,0.04,2,0.393546439612572,"*",0.249274,"BCL6B","NA","GO:0003676//nucleic acid binding","NA","K09228//KRAB domain-containing zinc finger protein","KFV50562.1//B-cell lymphoma 6 protein, partial [Gavia stellata]","3//A2MP1"]
[29999,1911,0.01,0.04,2,0.648039766523047,"*",0.499032,"FSCN3","GO:0005856//cytoskeleton;GO:0005902//microvillus;GO:0030027//lamellipodium;GO:0005737//cytoplasm;GO:0030175//filopodium;GO:0001726//ruffle;GO:0031253//cell projection membrane;GO:0030426//growth cone;GO:0015629//actin cytoskeleton;GO:0031941//filamentous actin","GO:0051015//actin filament binding;GO:0030674//protein binding, bridging","GO:0007015//actin filament organization;GO:0016477//cell migration;GO:0009653//anatomical structure morphogenesis;GO:0007163//establishment or maintenance of cell polarity;GO:0051017//actin filament bundle assembly;GO:0007286//spermatid development","K17456//fascin 3","XP_011727897.1//PREDICTED: fascin-3 isoform X2 [Macaca nemestrina]","2//1"]
[55089,3807,0.01,0.04,2,0.39342978717518,"*",0.249274,"SLC38A4","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0015293//symporter activity;GO:0015171//amino acid transmembrane transporter activity","GO:0006865//amino acid transport;GO:0003333//amino acid transmembrane transport;GO:0006814//sodium ion transport","K14991//solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 4","NP_060488.2//sodium-coupled neutral amino acid transporter 4 [Homo sapiens]","1//3;4"]
[7054,1898,0.01,0.04,2,0.647565976279448,"*",0.499032,"TH","GO:0005790//smooth endoplasmic reticulum;GO:0030424//axon;GO:0005634//nucleus;GO:0031410//cytoplasmic vesicle;GO:0033162//melanosome membrane;GO:0005737//cytoplasm;GO:0043204//perikaryon;GO:0005829//cytosol;GO:0009898//cytoplasmic side of plasma membrane","GO:0016597//amino acid binding;GO:0005506//iron ion binding;GO:0004511//tyrosine 3-monooxygenase activity;GO:0008199//ferric iron binding;GO:0035240//dopamine binding;GO:0019899//enzyme binding","GO:0042423//catecholamine biosynthetic process;GO:0007617//mating behavior;GO:0007601//visual perception;GO:0042418//epinephrine biosynthetic process;GO:0045471//response to ethanol;GO:0015842//aminergic neurotransmitter loading into synaptic vesicle;GO:0008016//regulation of heart contraction;GO:0048596//embryonic camera-type eye morphogenesis;GO:0009653//anatomical structure morphogenesis;GO:0042755//eating behavior;GO:0007507//heart development;GO:0006585//dopamine biosynthetic process from tyrosine;GO:0007612//learning;GO:0001666//response to hypoxia;GO:0009887//animal organ morphogenesis;GO:0007626//locomotory behavior;GO:0007613//memory;GO:0042421//norepinephrine biosynthetic process;GO:0001963//synaptic transmission, dopaminergic;GO:0042462//eye photoreceptor cell development","K00501//tyrosine 3-monooxygenase [EC:1.14.16.2]","NP_000351.2//tyrosine 3-monooxygenase isoform b [Homo sapiens];NP_954987.2//tyrosine 3-monooxygenase isoform c [Homo sapiens];NP_954986.2//tyrosine 3-monooxygenase isoform a [Homo sapiens]","3//A2MP1;2//1"]
[154197,1859,0.01,0.04,2,0.647408200113701,"*",0.499032,"PNLDC1","GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0004535//poly(A)-specific ribonuclease activity;GO:0003723//RNA binding;GO:0046872//metal ion binding;GO:0003676//nucleic acid binding","GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","K01148//poly(A)-specific ribonuclease [EC:3.1.13.4]","NP_775787.1//poly(A)-specific ribonuclease PNLDC1 isoform 2 precursor [Homo sapiens];NP_001258791.1//poly(A)-specific ribonuclease PNLDC1 isoform 1 [Homo sapiens]","1//3;2//1"]
[57451,9458,0.01,0.04,2,0.226964388118359,"*",0.1243658,"TENM2","NA","NA","NA","K06252//tenascin","XP_022273430.1//teneurin-2 isoform X2 [Canis lupus familiaris]","1//3;2//1"]
[5579,8014,0.01,0.04,2,0.127590965968923,"*",0.062198,"PRKCB","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0042393//histone binding;GO:0035403//histone kinase activity (H3-T6 specific);GO:0005524//ATP binding;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0004697//protein kinase C activity;GO:0005080//protein kinase C binding;GO:0004674//protein serine/threonine kinase activity;GO:0050681//androgen receptor binding;GO:0003682//chromatin binding;GO:0008270//zinc ion binding;GO:0005246//calcium channel regulator activity;GO:0004698//calcium-dependent protein kinase C activity","GO:0007077//mitotic nuclear envelope disassembly;GO:0050861//positive regulation of B cell receptor signaling pathway;GO:0030168//platelet activation;GO:0035556//intracellular signal transduction;GO:0045637//regulation of myeloid cell differentiation;GO:0035408//histone H3-T6 phosphorylation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0045766//positive regulation of angiogenesis;GO:0042953//lipoprotein transport;GO:0006874//cellular calcium ion homeostasis;GO:0050853//B cell receptor signaling pathway;GO:0007165//signal transduction;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0006468//protein phosphorylation;GO:0030949//positive regulation of vascular endothelial growth factor receptor signaling pathway;GO:0006351//transcription, DNA-templated;GO:0006816//calcium ion transport;GO:0001666//response to hypoxia;GO:0002250//adaptive immune response;GO:0006915//apoptotic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0071322//cellular response to carbohydrate stimulus;GO:0010829//negative regulation of glucose transport;GO:0018105//peptidyl-serine phosphorylation;GO:0042113//B cell activation","K19662//classical protein kinase C beta type [EC:2.7.11.13]","XP_021082023.1//protein kinase C beta type [Mesocricetus auratus];NP_002729.2//protein kinase C beta type isoform 2 [Homo sapiens]","6;2//1"]
[2165,2217,0.01,0.04,2,0.64620113229572,"*",0.499032,"F13B","GO:0005576//extracellular region","NA","GO:0007596//blood coagulation","K03906//coagulation factor XIII B polypeptide","NP_001985.2//coagulation factor XIII B chain precursor [Homo sapiens]","2//1"]
[1393,1854,0.01,0.04,2,0.646096382557951,"*",0.499032,"CRHBP","GO:0030425//dendrite;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0005874//microtubule;GO:0005622//intracellular;GO:0043204//perikaryon;GO:0043196//varicosity;GO:0030141//secretory granule;GO:0005767//secondary lysosome;GO:0031045//dense core granule;GO:0005576//extracellular region;GO:0005771//multivesicular body;GO:0043679//axon terminus","GO:0042277//peptide binding;GO:0051424//corticotropin-releasing hormone binding","GO:0033554//cellular response to stress;GO:0035690//cellular response to drug;GO:0071356//cellular response to tumor necrosis factor;GO:0051459//regulation of corticotropin secretion;GO:0071320//cellular response to cAMP;GO:2000310//regulation of NMDA receptor activity;GO:0097211//cellular response to gonadotropin-releasing hormone;GO:0071277//cellular response to calcium ion;GO:0007611//learning or memory;GO:0009755//hormone-mediated signaling pathway;GO:0035865//cellular response to potassium ion;GO:0048149//behavioral response to ethanol;GO:0007565//female pregnancy;GO:0051460//negative regulation of corticotropin secretion;GO:0007165//signal transduction;GO:0045055//regulated exocytosis;GO:1900011//negative regulation of corticotropin-releasing hormone receptor activity;GO:0071314//cellular response to cocaine;GO:0006954//inflammatory response;GO:0071391//cellular response to estrogen stimulus;GO:0001963//synaptic transmission, dopaminergic;GO:0071392//cellular response to estradiol stimulus","NA","NP_001873.2//corticotropin-releasing factor-binding protein precursor [Homo sapiens]","3//A2MP1"]
[9248,2020,0.01,0.04,2,0.645886984929509,"*",0.499032,"GPR50","GO:0005654//nucleoplasm;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0042802//identical protein binding;GO:0008502//melatonin receptor activity;GO:0004930//G-protein coupled receptor activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0007267//cell-cell signaling","K04287//G protein-coupled receptor 50","NP_004215.2//melatonin-related receptor [Homo sapiens]","3//A2MP1"]
[286234,4471,0.01,0.04,2,0.392808806944855,"*",0.249274,"SPATA31E1","GO:0016021//integral component of membrane","NA","GO:0030154//cell differentiation;GO:0007283//spermatogenesis","NA","NP_849150.3//spermatogenesis-associated protein 31E1 [Homo sapiens]",4]
[7447,2014,0.01,0.04,2,0.645573142857143,"*",0.499032,"VSNL1","NA","GO:0005509//calcium ion binding","NA","K19936//visinin-like protein 1","XP_012975277.1//visinin-like protein 1 isoform X1 [Mesocricetus auratus]",4]
[653509,2075,0.01,0.04,2,0.645364084196891,"*",0.499032,"SFTPA1","NA","NA","NA","K10067//pulmonary surfactant-associated protein A;K06237//collagen, type IV, alpha","XP_019811710.1//PREDICTED: collagen alpha-5(IV) chain isoform X1 [Bos indicus];NP_001158117.1//pulmonary surfactant-associated protein A1 isoform 3 precursor [Homo sapiens]","4;1//3;2//1"]
[1551,2099,0.01,0.04,2,0.645311840686473,"*",0.499032,"CYP3A7","GO:0016021//integral component of membrane","GO:0020037//heme binding;GO:0005506//iron ion binding;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen","NA","K17691//cytochrome P450 family 3 subfamily A polypeptide 7 [EC:1.14.14.1]","XP_016812378.1//PREDICTED: cytochrome P450, family 3, subfamily A, polypeptide 67 isoform X1 [Pan troglodytes]",4]
[55340,1895,0.01,0.04,2,0.644894196909635,"*",0.499032,"GIMAP5","GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane","GO:0005525//GTP binding","NA","K15261//poly [ADP-ribose] polymerase 10/14/15 [EC:2.4.2.30];K18626//trichohyalin","NP_001186506.1//GIMAP1-GIMAP5 protein isoform a [Homo sapiens]",4]
[81551,2234,0.01,0.04,2,0.644842029445074,"*",0.499032,"STMN4","GO:0030424//axon;GO:0030426//growth cone;GO:0005794//Golgi apparatus;GO:0005737//cytoplasm;GO:0043005//neuron projection","GO:0015631//tubulin binding","GO:0031110//regulation of microtubule polymerization or depolymerization;GO:0051493//regulation of cytoskeleton organization;GO:0031175//neuron projection development;GO:0007019//microtubule depolymerization","K12012//tripartite motif-containing protein 35;K04381//stathmin","EDL35996.1//stathmin-like 4, isoform CRA_d [Mus musculus];NP_001069048.1//stathmin-4 [Bos taurus];NP_110422.2//stathmin-4 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[10742,2079,0.01,0.04,2,0.644424993371059,"*",0.499032,"RAI2","NA","NA","GO:0009790//embryo development","K13096//splicing factor 4;K02367//glucuronyl/N-acetylglucosaminyl transferase EXT2 [EC:2.4.1.224 2.4.1.225]","NP_001166203.1//retinoic acid-induced protein 2 isoform 2 [Homo sapiens];NP_068557.3//retinoic acid-induced protein 2 isoform 1 [Homo sapiens]","4;1//3"]
[129852,1921,0.01,0.04,2,0.644216677549701,"*",0.499032,"C2orf73","NA","NA","NA","NA","NP_001093866.1//uncharacterized protein C2orf73 [Homo sapiens]","1//3"]
[220136,1864,0.01,0.04,2,0.644112570135747,"*",0.499032,"CFAP53","NA","NA","GO:0003341//cilium movement;GO:0060271//cilium assembly;GO:0007368//determination of left/right symmetry","K11589//methyl-CpG-binding domain protein 1;K05058//leukemia inhibitory factor receptor;K16811//trichoplein keratin filament-binding protein","XP_003827259.2//PREDICTED: cilia- and flagella-associated protein 53 [Pan paniscus]",4]
[8876,3844,0.02,0.08,2,0.355848251968504,"*",0.217844,"VNN1","GO:0070062//extracellular exosome;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0031225//anchored component of membrane;GO:0035577//azurophil granule membrane","GO:0017159//pantetheine hydrolase activity","GO:1902176//negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:0006501//C-terminal protein lipidation;GO:0033089//positive regulation of T cell differentiation in thymus;GO:0002526//acute inflammatory response;GO:0006954//inflammatory response;GO:0006979//response to oxidative stress;GO:0098609//cell-cell adhesion;GO:0006928//movement of cell or subcellular component;GO:0002544//chronic inflammatory response;GO:0015939//pantothenate metabolic process;GO:0043312//neutrophil degranulation;GO:0045087//innate immune response","K08069//pantetheine hydrolase [EC:3.5.1.92]","NP_004657.2//pantetheinase precursor [Homo sapiens]","2//1"]
[8572,2292,0.01,0.04,2,0.642762229317852,"*",0.499032,"PDLIM4","GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0030027//lamellipodium;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0001725//stress fiber;GO:0034777//recycling endosome lumen;GO:0043197//dendritic spine;GO:0045211//postsynaptic membrane;GO:0031905//early endosome lumen;GO:0031941//filamentous actin","GO:0046872//metal ion binding;GO:0051393//alpha-actinin binding;GO:0019903//protein phosphatase binding;GO:0042803//protein homodimerization activity","GO:0031532//actin cytoskeleton reorganization;GO:0098976//excitatory chemical synaptic transmission","K19867//LIM domain-binding protein 3","NP_001124499.1//PDZ and LIM domain protein 4 isoform 2 [Homo sapiens];NP_003678.2//PDZ and LIM domain protein 4 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[140691,1433,0.01,0.04,2,0.642503197227372,"*",0.499032,"TRIM69","GO:0005634//nucleus;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0004842//ubiquitin-protein transferase activity","GO:0000209//protein polyubiquitination;GO:0006915//apoptotic process","K12034//tripartite motif-containing protein 69 [EC:2.3.2.27]","XP_017716518.1//PREDICTED: E3 ubiquitin-protein ligase TRIM69 isoform X4 [Rhinopithecus bieti];NP_892030.3//E3 ubiquitin-protein ligase TRIM69 isoform a [Homo sapiens];NP_542783.2//E3 ubiquitin-protein ligase TRIM69 isoform b [Homo sapiens];XP_017716517.1//PREDICTED: E3 ubiquitin-protein ligase TRIM69 isoform X3 [Rhinopithecus bieti];NP_001288075.1//E3 ubiquitin-protein ligase TRIM69 isoform e [Homo sapiens]","1//3;4"]
[6005,1953,0.01,0.04,2,0.640901846599132,"*",0.499032,"RHAG","GO:0016020//membrane;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0008519//ammonium transmembrane transporter activity;GO:0022840//leak channel activity;GO:0035379//carbon dioxide transmembrane transporter activity;GO:0030506//ankyrin binding","GO:0015695//organic cation transport;GO:0060586//multicellular organismal iron ion homeostasis;GO:0015670//carbon dioxide transport;GO:0006873//cellular ion homeostasis;GO:0015696//ammonium transport;GO:0015701//bicarbonate transport;GO:0048821//erythrocyte development;GO:0072488//ammonium transmembrane transport;GO:0015672//monovalent inorganic cation transport","K06580//ammonium transporter Rh","NP_000315.2//ammonium transporter Rh type A [Homo sapiens]","2//1"]
[254050,1934,0.01,0.04,2,0.640438432393348,"*",0.499032,"LRRC43","NA","NA","NA","NA","XP_016874613.1//PREDICTED: leucine-rich repeat-containing protein 43 isoform X1 [Homo sapiens];NP_001091989.1//leucine-rich repeat-containing protein 43 isoform 1 [Homo sapiens]","1//3;4"]
[85508,3594,0.01,0.04,2,0.391842440070852,"*",0.249274,"SCRT2","NA","NA","NA","K09219//scratch","XP_016792752.1//PREDICTED: transcriptional repressor scratch 2 [Pan troglodytes]","3//A2MP1"]
[5055,1924,0.01,0.04,2,0.640335542453209,"*",0.499032,"SERPINB2","GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0004867//serine-type endopeptidase inhibitor activity","GO:0042730//fibrinolysis;GO:0042060//wound healing;GO:0043066//negative regulation of apoptotic process;GO:0035722//interleukin-12-mediated signaling pathway","K19821//plasminogen activator inhibitor 2","NP_002566.1//plasminogen activator inhibitor 2 [Homo sapiens]","1//3;2//1"]
[645027,2015,0.01,0.04,2,0.640078462180825,"*",0.499032,"EVPLL","GO:0001533//cornified envelope","GO:0005198//structural molecule activity;GO:0019215//intermediate filament binding","GO:0008544//epidermis development","K10383//envoplakin","NP_001138599.1//envoplakin-like protein [Homo sapiens]","1//3"]
[24,7326,0.01,0.04,2,0.355630051711804,"*",0.217844,"ABCA4","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0097381//photoreceptor disc membrane;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane","GO:0005524//ATP binding;GO:0090555//phosphatidylethanolamine-translocating ATPase activity;GO:0042626//ATPase activity, coupled to transmembrane movement of substances;GO:0005395//eye pigment precursor transporter activity;GO:0005215//transporter activity;GO:0016887//ATPase activity","GO:0006810//transport;GO:0055085//transmembrane transport;GO:0001523//retinoid metabolic process;GO:0007603//phototransduction, visible light;GO:0045332//phospholipid translocation;GO:0006649//phospholipid transfer to membrane;GO:0007601//visual perception;GO:0045494//photoreceptor cell maintenance","K05644//ATP-binding cassette, subfamily A (ABC1), member 4","NP_000341.2//retinal-specific ATP-binding cassette transporter [Homo sapiens]","2//1"]
[719,3555,0.01,0.04,2,0.391803884286136,"*",0.249274,"C3AR1","GO:0005887//integral component of plasma membrane;GO:0005623//cell;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane;GO:0005886//plasma membrane;GO:0035577//azurophil granule membrane","GO:0004876//complement component C3a receptor activity;GO:0004930//G-protein coupled receptor activity","GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway;GO:0030449//regulation of complement activation;GO:0090023//positive regulation of neutrophil chemotaxis;GO:0010575//positive regulation of vascular endothelial growth factor production;GO:0050900//leukocyte migration;GO:0010759//positive regulation of macrophage chemotaxis;GO:0006954//inflammatory response;GO:0008015//blood circulation;GO:0060326//cell chemotaxis;GO:0043312//neutrophil degranulation;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0006935//chemotaxis;GO:0045766//positive regulation of angiogenesis","K04009//C3a anaphylatoxin chemotactic receptor","NP_004045.1//C3a anaphylatoxin chemotactic receptor [Homo sapiens]","1//3;3//A2MP1"]
[158809,1949,0.01,0.04,2,0.639564920410783,"*",0.499032,"MAGEB6","NA","NA","NA","K12464//melanoma-associated antigen D1","NP_775794.2//melanoma-associated antigen B6 [Homo sapiens]","2//1"]
[344787,3210,0.05,0.2,2,0.203124322554984,"*",0.1086958,"ZNF860","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_014987882.1//PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 860 [Macaca mulatta]","2//1"]
[8013,5635,0.45,1.79,1.99196268093458,{"v":6.26535485855263e-14,"d":"6.27E-14"},"Up",{"v":4.76942e-15,"d":"4.77E-15"},"NR4A3","NA","NA","NA","K08559//nuclear receptor subfamily 4 group A member 3","XP_017383295.1//PREDICTED: nuclear receptor subfamily 4 group A member 3 isoform X1 [Cebus capucinus imitator];AAB36006.1//steroid/thyroid orphan receptor homolog gene, partial [Homo sapiens]","3//A2MP1;2//1"]
[161247,1064,0.08,0.31,1.95419631038688,0.355957452536825,"*",0.217844,"FITM1","NA","NA","NA","K09291//nucleoprotein TPR;K11801//WD repeat-containing protein 23","XP_005560985.1//PREDICTED: fat storage-inducing transmembrane protein 1 [Macaca fascicularis]","2//1"]
[146556,1933,0.08,0.31,1.95419631038688,0.0851397958230283,"*",0.038791,"C16orf89","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005829//cytosol","GO:0042803//protein homodimerization activity","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K22069//LYR motif-containing protein 4;K11447//histone demethylase [EC:1.14.11.-];K01064//wingless-type MMTV integration site family, member 9","AAQ88847.1//SARG904 [Homo sapiens];EAW85242.1//hypothetical protein MGC45438, isoform CRA_a [Homo sapiens]","4;2//1"]
[23066,4248,0.28,1.08,1.94753258010586,{"v":5.66631287052342e-07,"d":"5.67E-07"},"Up",{"v":9.01346e-08,"d":"9.01E-08"},"CAND2","GO:0005634//nucleus;GO:0005622//intracellular","GO:0017025//TBP-class protein binding","GO:0010265//SCF complex assembly;GO:0016567//protein ubiquitination;GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated","K17263//cullin-associated NEDD8-dissociated protein 1","XP_011839000.1//PREDICTED: cullin-associated NEDD8-dissociated protein 2 isoform X1 [Mandrillus leucophaeus];NP_036430.1//cullin-associated NEDD8-dissociated protein 2 isoform 2 [Homo sapiens]","1//3;2//1"]
[3112,1388,0.06,0.23,1.93859945533586,0.356139602497186,"*",0.217844,"HLA-DOB","GO:0005765//lysosomal membrane;GO:0010008//endosome membrane;GO:0042613//MHC class II protein complex;GO:0005622//intracellular;GO:0016021//integral component of membrane;GO:0005764//lysosome","GO:0032395//MHC class II receptor activity;GO:0023026//MHC class II protein complex binding","GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0002504//antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;GO:0006955//immune response;GO:0002587//negative regulation of antigen processing and presentation of peptide antigen via MHC class II","K06752//major histocompatibility complex, class II","XP_004043832.1//PREDICTED: HLA class II histocompatibility antigen, DO beta chain [Gorilla gorilla gorilla]","3//A2MP1"]
[5349,1380,0.06,0.23,1.93859945533586,0.356066720147345,"*",0.217844,"FXYD3","GO:0070062//extracellular exosome;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005216//ion channel activity;GO:0017080//sodium channel regulator activity;GO:0005254//chloride channel activity","GO:1903779//regulation of cardiac conduction;GO:0006813//potassium ion transport;GO:2000649//regulation of sodium ion transmembrane transporter activity;GO:0006821//chloride transport;GO:0034220//ion transmembrane transport;GO:0006814//sodium ion transport","K13361//FXYD domain-containing ion transport regulator 3","NP_001129481.1//FXYD domain-containing ion transport regulator 3 isoform 5 precursor [Homo sapiens];NP_001129479.1//FXYD domain-containing ion transport regulator 3 isoform 3 [Homo sapiens];AQN67652.1//FXYD domain-containing ion transport regulator 3 [Homo sapiens];XP_011525334.1//PREDICTED: FXYD domain-containing ion transport regulator 3 isoform X1 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[51129,1905,4.59,17.58,1.9373690117296,{"v":1.62537699859155E-41,"d":"1.63E-41"},"Up",{"v":2.88974e-43,"d":"2.89E-43"},"ANGPTL4","GO:0005615//extracellular space;GO:0072562//blood microparticle;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix","GO:0042802//identical protein binding;GO:0004857//enzyme inhibitor activity","GO:0051005//negative regulation of lipoprotein lipase activity;GO:0030154//cell differentiation;GO:0001525//angiogenesis;GO:0051260//protein homooligomerization;GO:0043066//negative regulation of apoptotic process;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:0001666//response to hypoxia;GO:0070328//triglyceride homeostasis;GO:0019216//regulation of lipid metabolic process;GO:0045766//positive regulation of angiogenesis","K08767//angiopoietin-like 4","AAQ88642.1//NL2 [Homo sapiens]","2//1"]
[374918,771,0.54,2.06,1.93161302501975,0.0114302464991983,"*",0.0040164,"IGFL1","GO:0005615//extracellular space","NA","NA","NA","NP_940943.1//insulin growth factor-like family member 1 precursor [Homo sapiens]","1//3"]
[79689,4532,0.13,0.49,1.91427012597412,2.80891328760972E-3,"*",8.61454E-4,"STEAP4","GO:0070062//extracellular exosome;GO:0005768//endosome;GO:0031901//early endosome membrane;GO:0005887//integral component of plasma membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0000139//Golgi membrane","GO:0008823//cupric reductase activity;GO:0046872//metal ion binding;GO:0052851//ferric-chelate reductase (NADPH) activity","GO:0055072//iron ion homeostasis;GO:0098706//ferric iron import across plasma membrane;GO:0045444//fat cell differentiation;GO:0015677//copper ion import","K19876//metalloreductase STEAP4 [EC:1.16.1.-]","NP_001192245.1//metalloreductase STEAP4 isoform 2 [Homo sapiens];NP_078912.2//metalloreductase STEAP4 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[389289,1280,1.59,5.98,1.91111871891375,{"v":7.11608308022599e-10,"d":"7.12E-10"},"Up",{"v":7.88498e-11,"d":"7.88E-11"},"ANXA2R","NA","GO:0004872//receptor activity","NA","NA","XP_004058948.1//PREDICTED: annexin-2 receptor [Gorilla gorilla gorilla]","2//1"]
[6404,2573,0.19,0.71,1.9018196060611,0.00440197710509804,"*",1.405414E-3,"SELPLG","GO:0016020//membrane;GO:0005887//integral component of plasma membrane;GO:0044853//plasma membrane raft;GO:0016021//integral component of membrane;GO:0001931//uropod;GO:0005886//plasma membrane","GO:0005102//receptor binding;GO:0001618//virus receptor activity","GO:0007155//cell adhesion;GO:0071354//cellular response to interleukin-6;GO:0050900//leukocyte migration;GO:0050902//leukocyte adhesive activation;GO:0050901//leukocyte tethering or rolling","K06544//selectin P ligand","NP_001193538.1//P-selectin glycoprotein ligand 1 isoform 1 precursor [Homo sapiens]","4;1//3"]
[23308,3013,0.93,3.47,1.89963304147023,{"v":3.93209515731874E-8,"d":"3.93E-08"},"Up",{"v":5.3982e-09,"d":"5.40E-09"},"ICOSLG","GO:0070062//extracellular exosome;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005102//receptor binding","GO:0042110//T cell activation;GO:0007165//signal transduction;GO:0031295//T cell costimulation;GO:0002250//adaptive immune response;GO:0006972//hyperosmotic response;GO:0006952//defense response;GO:0042113//B cell activation;GO:0042104//positive regulation of activated T cell proliferation","K06710//inducible T-cell co-stimulator ligand","XP_016883799.1//PREDICTED: ICOS ligand isoform X4 [Homo sapiens];NP_001269980.1//ICOS ligand isoform c precursor [Homo sapiens];BAA31628.1//KIAA0653 protein, partial [Homo sapiens]","1//3;5"]
[8743,1943,0.11,0.41,1.89812038598079,0.0842476025913163,"*",0.0382632,"TNFSF10","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005576//extracellular region","GO:0005164//tumor necrosis factor receptor binding;GO:0005125//cytokine activity;GO:0042802//identical protein binding;GO:0008270//zinc ion binding;GO:0005102//receptor binding","GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007165//signal transduction;GO:0032868//response to insulin;GO:0097296//activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway;GO:0007267//cell-cell signaling;GO:0007166//cell surface receptor signaling pathway;GO:0008584//male gonad development;GO:0006915//apoptotic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:1902041//regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0043065//positive regulation of apoptotic process;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0006955//immune response;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors","K04721//tumor necrosis factor ligand superfamily member 10","NP_003801.1//tumor necrosis factor ligand superfamily member 10 isoform 1 [Homo sapiens];EAW78467.1//tumor necrosis factor (ligand) superfamily, member 10, isoform CRA_c, partial [Homo sapiens];NP_001177872.1//tumor necrosis factor ligand superfamily member 10 isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[445577,1154,0.2,0.74,1.88752527074159,0.052227096239718,"*",0.0222588,"C9orf129","GO:0005634//nucleus","NA","GO:0035357//peroxisome proliferator activated receptor signaling pathway;GO:0045444//fat cell differentiation","NA","NP_001092278.1//putative uncharacterized protein C9orf129 [Homo sapiens]","1//3"]
[3553,1498,0.16,0.59,1.88264304936184,0.0775109479314668,"*",0.0348348,"IL1B","GO:0070062//extracellular exosome;GO:0030141//secretory granule;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005576//extracellular region","GO:0019904//protein domain specific binding;GO:0005125//cytokine activity;GO:0005149//interleukin-1 receptor binding","GO:0071407//cellular response to organic cyclic compound;GO:0071260//cellular response to mechanical stimulus;GO:0035690//cellular response to drug;GO:0000187//activation of MAPK activity;GO:0007267//cell-cell signaling;GO:0006915//apoptotic process","K04519//interleukin 1 beta","EAW73607.1//interleukin 1, beta, isoform CRA_c [Homo sapiens]","2//1"]
[64090,1449,0.06,0.22,1.87446911791614,0.356248981981982,"*",0.217844,"GAL3ST2","GO:0016020//membrane;GO:0032580//Golgi cisterna membrane;GO:0016021//integral component of membrane","GO:0008146//sulfotransferase activity;GO:0001733//galactosylceramide sulfotransferase activity","GO:0009247//glycolipid biosynthetic process","K09675//galactose-3-O-sulfotransferase 2 [EC:2.8.2.-]","NP_071417.2//galactose-3-O-sulfotransferase 2 [Homo sapiens]","2//1"]
[1305,2816,0.03,0.11,1.87446911791614,0.356176054861822,"*",0.217844,"COL13A1","NA","NA","NA","K16617//collagen, type XIII, alpha","XP_005968572.1//PREDICTED: LOW QUALITY PROTEIN: collagen alpha-1(XIII) chain [Pantholops hodgsonii];XP_012618095.1//collagen alpha-1(XIII) chain isoform X7 [Microcebus murinus];XP_018891109.1//PREDICTED: collagen alpha-1(XIII) chain isoform X5 [Gorilla gorilla gorilla];XP_021799086.1//collagen alpha-1(XIII) chain isoform X2 [Papio anubis]","1//3;3//A2MP1"]
[7544,4989,0.03,0.11,1.87446911791614,0.20321941821161,"*",0.1086958,"ZFY","GO:0005654//nucleoplasm;GO:0005730//nucleolus","GO:0046872//metal ion binding;GO:0003677//DNA binding","GO:0006355//regulation of transcription, DNA-templated;GO:0007275//multicellular organism development;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","NP_003402.2//zinc finger Y-chromosomal protein isoform 1 [Homo sapiens];XP_011529777.1//PREDICTED: zinc finger Y-chromosomal protein isoform X3 [Homo sapiens];NP_001138748.1//zinc finger Y-chromosomal protein isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[3164,3040,31.54,115.21,1.8690113800485,0,"Up",0,"NR4A1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0005667//transcription factor complex;GO:0005829//cytosol","GO:0003707//steroid hormone receptor activity;GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity;GO:0035259//glucocorticoid receptor binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0042803//protein homodimerization activity;GO:0004879//nuclear receptor activity;GO:0043565//sequence-specific DNA binding;GO:0008270//zinc ion binding;GO:0008134//transcription factor binding","GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0071376//cellular response to corticotropin-releasing hormone stimulus;GO:0045786//negative regulation of cell cycle;GO:0035767//endothelial cell chemotaxis;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0061469//regulation of type B pancreatic cell proliferation;GO:0043065//positive regulation of apoptotic process;GO:0002042//cell migration involved in sprouting angiogenesis;GO:0001938//positive regulation of endothelial cell proliferation;GO:0007165//signal transduction;GO:0006351//transcription, DNA-templated;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0006915//apoptotic process;GO:0035914//skeletal muscle cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045444//fat cell differentiation;GO:0006367//transcription initiation from RNA polymerase II promoter","K04465//nuclear receptor subfamily 4 group A member 1","XP_016874736.1//PREDICTED: nuclear receptor subfamily 4 group A member 1 isoform X2 [Homo sapiens];NP_001189163.1//nuclear receptor subfamily 4 group A member 1 isoform 3 [Homo sapiens]","4;1//3;2//1"]
[3431,2112,2.01,7.31,1.86267590477351,{"v":4.52040766259169E-19,"d":"4.52E-19"},"Up",{"v":2.31482e-20,"d":"2.31E-20"},"SP110","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0004871//signal transducer activity","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0016032//viral process","K15413//nuclear autoantigen Sp-100","NP_004500.3//sp110 nuclear body protein isoform a [Homo sapiens];NP_001171944.1//sp110 nuclear body protein isoform d [Homo sapiens];NP_536349.2//sp110 nuclear body protein isoform c [Homo sapiens];NP_004501.3//sp110 nuclear body protein isoform b [Homo sapiens]","1//3;3//A2MP1;2//1"]
[4939,2807,0.08,0.29,1.85798099512757,0.255200835110132,"*",0.1450622,"OAS2","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005654//nucleoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm","GO:0046872//metal ion binding;GO:0005524//ATP binding;GO:0008270//zinc ion binding;GO:0001730//2'-5'-oligoadenylate synthetase activity;GO:0016740//transferase activity;GO:0003725//double-stranded RNA binding","GO:0006401//RNA catabolic process;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0060337//type I interferon signaling pathway;GO:0006486//protein glycosylation;GO:0051607//defense response to virus;GO:0006139//nucleobase-containing compound metabolic process;GO:0006955//immune response;GO:0006164//purine nucleotide biosynthetic process;GO:0009615//response to virus;GO:0018377//protein myristoylation","K14216//2'-5'-oligoadenylate synthetase [EC:2.7.7.84]","NP_001027903.1//2'-5'-oligoadenylate synthase 2 isoform 3 [Homo sapiens];NP_002526.2//2'-5'-oligoadenylate synthase 2 isoform 2 [Homo sapiens];EAW98026.1//2'-5'-oligoadenylate synthetase 2, 69/71kDa, isoform CRA_a [Homo sapiens]","1//3;2//1"]
[93659,880,0.62,2.23,1.84670358953343,0.00440111414154087,"*",1.405414E-3,"CGB5","GO:0005576//extracellular region","GO:0005179//hormone activity","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0016486//peptide hormone processing;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0007292//female gamete generation;GO:0006915//apoptotic process","K10045//chorionic gonadotropin, beta polypeptide","Q6NT52.4//RecName: Full=Choriogonadotropin subunit beta variant 2; Flags: Precursor","1//3"]
[9246,1285,24.63,88.46,1.84460861439969,{"v":1.021163052e-132,"d":"1.02E-132"},"Up",{"v":4.47486e-135,"d":"4.47E-135"},"UBE2L6","GO:0005654//nucleoplasm;GO:0005829//cytosol","GO:0043130//ubiquitin binding;GO:0005524//ATP binding;GO:0042296//ISG15 transferase activity;GO:0004842//ubiquitin-protein transferase activity","GO:0044267//cellular protein metabolic process;GO:0019985//translesion synthesis;GO:0032020//ISG15-protein conjugation;GO:0006464//cellular protein modification process;GO:0032480//negative regulation of type I interferon production;GO:0019941//modification-dependent protein catabolic process","K04553//ubiquitin-conjugating enzyme E2 L6 [EC:2.3.2.23]","EAW73755.1//ubiquitin-conjugating enzyme E2L 6, isoform CRA_a, partial [Homo sapiens];XP_017706859.1//PREDICTED: ubiquitin/ISG15-conjugating enzyme E2 L6 [Rhinopithecus bieti]","4;2//1"]
[57402,1075,0.15,0.53,1.82102985895468,0.203266999438071,"*",0.1086958,"S100A14","GO:0070062//extracellular exosome;GO:0016604//nuclear body;GO:0005829//cytosol;GO:0030054//cell junction;GO:0048471//perinuclear region of cytoplasm","GO:0005509//calcium ion binding;GO:0042379//chemokine receptor binding","GO:0071624//positive regulation of granulocyte chemotaxis;GO:0090026//positive regulation of monocyte chemotaxis;GO:0032496//response to lipopolysaccharide;GO:0042742//defense response to bacterium;GO:0055074//calcium ion homeostasis;GO:0034142//toll-like receptor 4 signaling pathway;GO:0006915//apoptotic process","NA","NP_065723.1//protein S100-A14 [Homo sapiens]","2//1"]
[4837,1579,46.38,163.67,1.8192151812141,{"v":7.57606885E-295,"d":"7.58E-295"},"Up",{"v":7.5884e-298,"d":"7.59E-298"},"NNMT","GO:0005829//cytosol","GO:0030760//pyridine N-methyltransferase activity;GO:0008112//nicotinamide N-methyltransferase activity","GO:0031100//animal organ regeneration;GO:0042493//response to drug;GO:0034356//NAD biosynthesis via nicotinamide riboside salvage pathway;GO:0010243//response to organonitrogen compound;GO:0032259//methylation","K00541//nicotinamide N-methyltransferase [EC:2.1.1.1]","NP_006160.1//nicotinamide N-methyltransferase [Homo sapiens]","2//1"]
[146325,2245,0.04,0.14,1.8073549220576,0.356358428673835,"*",0.217844,"PRR35","NA","NA","NA","K16628//collagen, type VII, alpha;K08582//calpain-15 [EC:3.4.22.-];K18808//toll-like receptor 13","NP_660313.1//proline-rich protein 35 [Homo sapiens]","2//1"]
[885,759,0.22,0.77,1.8073549220576,0.203195635950848,"*",0.1086958,"CCK","GO:0030425//dendrite;GO:0030424//axon;GO:0005615//extracellular space;GO:0043194//axon initial segment;GO:0043203//axon hillock;GO:0005576//extracellular region;GO:0043195//terminal bouton;GO:0043204//perikaryon","GO:0005184//neuropeptide hormone activity;GO:0005179//hormone activity","GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0007165//signal transduction;GO:0042755//eating behavior;GO:0014049//positive regulation of glutamate secretion;GO:0051901//positive regulation of mitochondrial depolarization;GO:0032099//negative regulation of appetite;GO:0001662//behavioral fear response;GO:0007409//axonogenesis;GO:0032461//positive regulation of protein oligomerization;GO:0001764//neuron migration;GO:0051930//regulation of sensory perception of pain;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0001836//release of cytochrome c from mitochondria;GO:0008284//positive regulation of cell proliferation","K05226//cholecystokinin","NP_000720.1//cholecystokinin preproprotein [Homo sapiens]","2//1;5"]
[5923,5382,0.02,0.07,1.8073549220576,0.356103157593123,"*",0.217844,"RASGRF1","GO:0030426//growth cone;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005886//plasma membrane;GO:0043005//neuron projection","GO:0035254//glutamate receptor binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005089//Rho guanyl-nucleotide exchange factor activity","GO:0034976//response to endoplasmic reticulum stress;GO:0035556//intracellular signal transduction;GO:0043547//positive regulation of GTPase activity;GO:0007616//long-term memory;GO:2000310//regulation of NMDA receptor activity;GO:0046578//regulation of Ras protein signal transduction;GO:0008283//cell proliferation;GO:0046579//positive regulation of Ras protein signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0048168//regulation of neuronal synaptic plasticity;GO:0031175//neuron projection development;GO:0090630//activation of GTPase activity;GO:0000165//MAPK cascade;GO:0007165//signal transduction;GO:0035020//regulation of Rac protein signal transduction;GO:0035023//regulation of Rho protein signal transduction;GO:0048167//regulation of synaptic plasticity","K04349//Ras-specific guanine nucleotide-releasing factor 1","NP_001139120.1//ras-specific guanine nucleotide-releasing factor 1 isoform 3 [Homo sapiens];AAA58417.1//CDC25 [Homo sapiens];NP_002882.3//ras-specific guanine nucleotide-releasing factor 1 isoform 1 [Homo sapiens]","1//3;4;2//1"]
[10568,4164,0.02,0.07,1.8073549220576,0.53046565920398,"*",0.37379,"SLC34A2","GO:0005903//brush border;GO:0016324//apical plasma membrane;GO:0031526//brush border membrane;GO:0031982//vesicle;GO:0005737//cytoplasm;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0042301//phosphate ion binding;GO:0005436//sodium:phosphate symporter activity;GO:0031402//sodium ion binding;GO:0015321//sodium-dependent phosphate transmembrane transporter activity","GO:0044267//cellular protein metabolic process;GO:0006817//phosphate ion transport;GO:0030643//cellular phosphate ion homeostasis;GO:0001701//in utero embryonic development;GO:0043627//response to estrogen","K14683//solute carrier family 34 (sodium-dependent phosphate cotransporter)","NP_001171469.1//sodium-dependent phosphate transport protein 2B isoform b [Homo sapiens];NP_006415.2//sodium-dependent phosphate transport protein 2B isoform a [Homo sapiens]","1//3;2//1"]
[4776,4630,0.02,0.07,1.8073549220576,0.356030290157561,"*",0.217844,"NFATC4","GO:0005634//nucleus;GO:0005667//transcription factor complex;GO:0005829//cytosol;GO:0016607//nuclear speck","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003713//transcription coactivator activity;GO:0008134//transcription factor binding;GO:0001227//transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0042975//peroxisome proliferator activated receptor binding","GO:0055001//muscle cell development;GO:0030178//negative regulation of Wnt signaling pathway;GO:0034644//cellular response to UV;GO:0032760//positive regulation of tumor necrosis factor production;GO:0032091//negative regulation of protein binding;GO:0033173//calcineurin-NFAT signaling cascade;GO:0045333//cellular respiration;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0007507//heart development;GO:0050774//negative regulation of dendrite morphogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0051145//smooth muscle cell differentiation;GO:0006954//inflammatory response;GO:2001235//positive regulation of apoptotic signaling pathway;GO:1904637//cellular response to ionomycin;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:2000297//negative regulation of synapse maturation;GO:0035562//negative regulation of chromatin binding;GO:0001569//branching involved in blood vessel morphogenesis;GO:1902894//negative regulation of pri-miRNA transcription from RNA polymerase II promoter;GO:0071285//cellular response to lithium ion;GO:0048167//regulation of synaptic plasticity","K17334//nuclear factor of activated T-cells, cytoplasmic 4","NP_004545.2//nuclear factor of activated T-cells, cytoplasmic 4 isoform 2 [Homo sapiens];NP_001185896.1//nuclear factor of activated T-cells, cytoplasmic 4 isoform 5 [Homo sapiens];NP_001275731.1//nuclear factor of activated T-cells, cytoplasmic 4 isoform 6 [Homo sapiens];NP_001129494.1//nuclear factor of activated T-cells, cytoplasmic 4 isoform 1 [Homo sapiens];NP_001306972.1//nuclear factor of activated T-cells, cytoplasmic 4 isoform 7 [Homo sapiens]","1//3;4;2//1"]
[9379,6149,0.02,0.07,1.8073549220576,0.530041851753218,"*",0.37379,"NRXN2","GO:0043234//protein complex;GO:0098793//presynapse;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0097109//neuroligin family protein binding;GO:0046872//metal ion binding;GO:0050839//cell adhesion molecule binding;GO:0004888//transmembrane signaling receptor activity;GO:0005246//calcium channel regulator activity","GO:0097116//gephyrin clustering involved in postsynaptic density assembly;GO:0035176//social behavior;GO:0007165//signal transduction;GO:0097104//postsynaptic membrane assembly;GO:0007416//synapse assembly;GO:0042297//vocal learning;GO:0007269//neurotransmitter secretion;GO:0097118//neuroligin clustering involved in postsynaptic membrane assembly;GO:0030534//adult behavior;GO:0007268//chemical synaptic transmission;GO:0071625//vocalization behavior;GO:0007158//neuron cell-cell adhesion;GO:0097119//postsynaptic density protein 95 clustering","K07377//neurexin","XP_004394041.1//PREDICTED: neurexin-2-beta isoform X1 [Odobenus rosmarus divergens];NP_620060.1//neurexin-2-beta isoform alpha-2 precursor [Homo sapiens];NP_620063.1//neurexin-2-beta isoform beta precursor [Homo sapiens]","3//A2MP1;2//1"]
[56122,3973,0.02,0.07,1.8073549220576,0.52966570212011,"*",0.37379,"PCDHB14","GO:0005887//integral component of plasma membrane","GO:0005509//calcium ion binding","GO:0007416//synapse assembly;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007268//chemical synaptic transmission","K16494//protocadherin beta","XP_002816041.3//PREDICTED: uncharacterized protein LOC100450339 [Pongo abelii]","3//A2MP1"]
[390205,2230,0.04,0.14,1.8073549220576,0.355775488804826,"*",0.217844,"LRRC10B","NA","NA","NA","K16175//protein scribble;K17277//epidermal growth factor receptor kinase substrate 8","NP_001138549.1//leucine-rich repeat-containing protein 10B [Homo sapiens]","1//3"]
[4973,2440,0.2,0.7,1.8073549220576,0.0105184680100756,"*",0.0036598,"OLR1","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0005654//nucleoplasm;GO:0043235//receptor complex;GO:0005887//integral component of plasma membrane;GO:0045121//membrane raft;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane;GO:0005886//plasma membrane;GO:0070821//tertiary granule membrane","GO:0005041//low-density lipoprotein receptor activity;GO:0030246//carbohydrate binding;GO:0042802//identical protein binding","GO:0008015//blood circulation;GO:0007155//cell adhesion;GO:0006508//proteolysis;GO:0050900//leukocyte migration;GO:0043312//neutrophil degranulation;GO:0006954//inflammatory response","K08763//oxidised low-density lipoprotein receptor 1","NP_001166103.1//oxidized low-density lipoprotein receptor 1 isoform 2 [Homo sapiens];NP_001166104.1//oxidized low-density lipoprotein receptor 1 isoform 3 [Homo sapiens];NP_002534.1//oxidized low-density lipoprotein receptor 1 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[85441,8889,1.98,6.81,1.78215436793246,{"v":6.04282407719298e-61,"d":"6.04E-61"},"Up",{"v":6.46878e-63,"d":"6.47E-63"},"HELZ2","GO:0016020//membrane;GO:0005654//nucleoplasm","GO:0003723//RNA binding;GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0005524//ATP binding;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0004386//helicase activity","GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0019216//regulation of lipid metabolic process;GO:0006351//transcription, DNA-templated","K16628//collagen, type VII, alpha","NP_208384.3//helicase with zinc finger domain 2 isoform 2 [Homo sapiens];XP_017736734.1//PREDICTED: helicase with zinc finger domain 2 isoform X2 [Rhinopithecus bieti]","3//A2MP1;2//1"]
[639,5017,0.68,2.33,1.77672330340394,{"v":5.66852571900827e-14,"d":"5.67E-14"},"Up",{"v":4.2938e-15,"d":"4.29E-15"},"PRDM1","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0042826//histone deacetylase binding;GO:1990841//promoter-specific chromatin binding;GO:0003676//nucleic acid binding;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:1990654//sebum secreting cell proliferation;GO:0031665//negative regulation of lipopolysaccharide-mediated signaling pathway;GO:0032823//regulation of natural killer cell differentiation;GO:0001763//morphogenesis of a branching structure;GO:0009791//post-embryonic development;GO:0003170//heart valve development;GO:0035904//aorta development;GO:0060576//intestinal epithelial cell development;GO:0003281//ventricular septum development;GO:0001893//maternal placenta development;GO:0060976//coronary vasculature development;GO:0051136//regulation of NK T cell differentiation;GO:0045165//cell fate commitment;GO:0033082//regulation of extrathymic T cell differentiation;GO:0045579//positive regulation of B cell differentiation;GO:0010628//positive regulation of gene expression;GO:0060707//trophoblast giant cell differentiation;GO:0007281//germ cell development;GO:0048844//artery morphogenesis;GO:0030889//negative regulation of B cell proliferation;GO:0042462//eye photoreceptor cell development","K09228//KRAB domain-containing zinc finger protein","XP_012293896.1//PR domain zinc finger protein 1 isoform X1 [Aotus nancymaae];XP_017399256.1//PREDICTED: PR domain zinc finger protein 1 isoform X3 [Cebus capucinus imitator]","3//A2MP1;2//1"]
[151636,5768,5.86,20.05,1.77462966692003,{"v":8.86296016338028e-131,"d":"8.86E-131"},"Up",{"v":3.93934e-133,"d":"3.94E-133"},"DTX3L","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0043234//protein complex;GO:0005829//cytosol;GO:0005764//lysosome;GO:0005737//cytoplasm","GO:0042393//histone binding;GO:0003723//RNA binding;GO:0097677//STAT family protein binding;GO:0004842//ubiquitin-protein transferase activity;GO:0046872//metal ion binding;GO:0004857//enzyme inhibitor activity;GO:0044389//ubiquitin-like protein ligase binding;GO:0008047//enzyme activator activity;GO:0019899//enzyme binding","GO:0070936//protein K48-linked ubiquitination;GO:0051444//negative regulation of ubiquitin-protein transferase activity;GO:0010390//histone monoubiquitination;GO:1902966//positive regulation of protein localization to early endosome;GO:1901666//positive regulation of NAD+ ADP-ribosyltransferase activity;GO:0035563//positive regulation of chromatin binding;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:2000646//positive regulation of receptor catabolic process;GO:2001034//positive regulation of double-strand break repair via nonhomologous end joining;GO:0045893//positive regulation of transcription, DNA-templated;GO:0032092//positive regulation of protein binding;GO:0006302//double-strand break repair;GO:0051865//protein autoubiquitination;GO:0008333//endosome to lysosome transport;GO:0006974//cellular response to DNA damage stimulus;GO:0000209//protein polyubiquitination;GO:1900182//positive regulation of protein localization to nucleus;GO:0033522//histone H2A ubiquitination;GO:0033523//histone H2B ubiquitination;GO:0002230//positive regulation of defense response to virus by host","K06058//deltex [EC:2.3.2.27]","NP_612144.1//E3 ubiquitin-protein ligase DTX3L [Homo sapiens]","3//A2MP1"]
[2243,2283,1.4,4.77,1.76856243906054,{"v":1.35023908545994E-12,"d":"1.35E-12"},"Up",{"v":1.139428e-13,"d":"1.14E-13"},"FGA","GO:0070062//extracellular exosome;GO:0005788//endoplasmic reticulum lumen;GO:0005577//fibrinogen complex;GO:0005615//extracellular space;GO:0072562//blood microparticle;GO:0009897//external side of plasma membrane;GO:0005938//cell cortex;GO:1903561//extracellular vesicle;GO:0031093//platelet alpha granule lumen;GO:0009986//cell surface;GO:0031091//platelet alpha granule;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0050839//cell adhesion molecule binding;GO:0046872//metal ion binding;GO:0030674//protein binding, bridging;GO:0005198//structural molecule activity;GO:0005102//receptor binding","GO:0043687//post-translational protein modification;GO:0007596//blood coagulation;GO:0030168//platelet activation;GO:0045921//positive regulation of exocytosis;GO:0072377//blood coagulation, common pathway;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:0044267//cellular protein metabolic process;GO:0002576//platelet degranulation;GO:0045907//positive regulation of vasoconstriction;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0043152//induction of bacterial agglutination;GO:0072378//blood coagulation, fibrin clot formation;GO:0090277//positive regulation of peptide hormone secretion;GO:0045087//innate immune response;GO:0034116//positive regulation of heterotypic cell-cell adhesion;GO:0042730//fibrinolysis;GO:0007165//signal transduction;GO:2000261//negative regulation of blood coagulation, common pathway;GO:0002224//toll-like receptor signaling pathway;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:0002250//adaptive immune response;GO:0031639//plasminogen activation;GO:0051258//protein polymerization;GO:0050714//positive regulation of protein secretion;GO:0007160//cell-matrix adhesion;GO:0051592//response to calcium ion;GO:0030198//extracellular matrix organization;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0006461//protein complex assembly;GO:0070527//platelet aggregation;GO:0043623//cellular protein complex assembly","K03903//fibrinogen alpha chain","NP_068657.1//fibrinogen alpha chain isoform alpha precursor [Homo sapiens];NP_000499.1//fibrinogen alpha chain isoform alpha-E preproprotein [Homo sapiens]","4;3//A2MP1"]
[5696,1390,6.64,22.62,1.7683437826429,{"v":1.7715166e-34,"d":"1.77E-34"},"Up",{"v":3.9924e-36,"d":"3.99E-36"},"PSMB8","NA","NA","NA","K02740//20S proteasome subunit beta 8 [EC:3.4.25.1]","XP_011727341.1//PREDICTED: proteasome subunit beta type-8 isoform X2 [Macaca nemestrina];XP_008992471.1//PREDICTED: LOW QUALITY PROTEIN: proteasome subunit beta type-8 [Callithrix jacchus]","4;3//A2MP1"]
[8858,1489,0.16,0.54,1.75488750216347,0.118413622146952,"*",0.0569014,"PROZ","GO:0070062//extracellular exosome;GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0005796//Golgi lumen","GO:0004252//serine-type endopeptidase activity;GO:0005509//calcium ion binding","GO:0030195//negative regulation of blood coagulation;GO:0007596//blood coagulation;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0006465//signal peptide processing;GO:0017187//peptidyl-glutamic acid carboxylation","K01314//coagulation factor X [EC:3.4.21.6]","NP_003882.1//vitamin K-dependent protein Z isoform 2 precursor [Homo sapiens];XP_016876301.1//PREDICTED: vitamin K-dependent protein Z isoform X1 [Homo sapiens]","1//3;2//1"]
[100288485,1494,0.16,0.54,1.75488750216347,0.118398197681386,"*",0.0569014,"MTRNR2L7","NA","NA","NA","NA","NA","1//3"]
[64816,1404,0.11,0.37,1.75002174699165,0.140025042669008,"*",0.0698898,"CYP3A43","GO:0031090//organelle membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0020037//heme binding;GO:0005506//iron ion binding;GO:0070330//aromatase activity;GO:0004497//monooxygenase activity;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen","NA","K17689//cytochrome P450 family 3 subfamily A polypeptide 4 [EC:1.14.13.32 1.14.13.67 1.14.13.97 1.14.13.157 1.14.13.-];K07424//cytochrome P450 family 3 subfamily A [EC:1.14.14.1];K17690//cytochrome P450 family 3 subfamily A polypeptide 5 [EC:1.14.14.1];K17692//cytochrome P450 family 3 subfamily A polypeptide 43 [EC:1.14.14.1]","NP_001265850.1//cytochrome P450 3A43 isoform 4 [Homo sapiens];CAD91343.1//cytochrome P450 [Homo sapiens];EHH52028.1//hypothetical protein EGM_12392 [Macaca fascicularis];XP_011799240.1//PREDICTED: cytochrome P450 3A43 isoform X3 [Colobus angolensis palliatus]","1//3;4;3//A2MP1;2//1"]
[27035,2382,0.03,0.1,1.73696559416621,0.531457183800623,"*",0.37379,"NOX1","GO:0071438//invadopodium membrane;GO:0043020//NADPH oxidase complex;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0005886//plasma membrane;GO:0005769//early endosome","GO:0050661//NADP binding;GO:0046872//metal ion binding;GO:0048365//Rac GTPase binding;GO:0030171//voltage-gated proton channel activity;GO:0016175//superoxide-generating NADPH oxidase activity","GO:0006801//superoxide metabolic process;GO:0008217//regulation of blood pressure;GO:0046330//positive regulation of JNK cascade;GO:0051454//intracellular pH elevation;GO:0006739//NADP metabolic process;GO:0016477//cell migration;GO:0010575//positive regulation of vascular endothelial growth factor production;GO:0055114//oxidation-reduction process;GO:1990451//cellular stress response to acidic pH;GO:0045726//positive regulation of integrin biosynthetic process;GO:1902177//positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:0042554//superoxide anion generation;GO:0015992//proton transport;GO:0007165//signal transduction;GO:0001525//angiogenesis;GO:0042743//hydrogen peroxide metabolic process;GO:0045730//respiratory burst;GO:0006954//inflammatory response;GO:0072592//oxygen metabolic process;GO:0030198//extracellular matrix organization;GO:0071455//cellular response to hyperoxia;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0003081//regulation of systemic arterial blood pressure by renin-angiotensin;GO:0008284//positive regulation of cell proliferation","K08008//NADPH oxidase 1","XP_010378484.1//PREDICTED: NADPH oxidase 1 isoform X1 [Rhinopithecus roxellana];XP_010378486.1//PREDICTED: NADPH oxidase 1 isoform X3 [Rhinopithecus roxellana];XP_010378485.1//PREDICTED: NADPH oxidase 1 isoform X2 [Rhinopithecus roxellana]","4;1//3;2//1"]
[254268,3063,0.03,0.1,1.73696559416621,0.356212514689323,"*",0.217844,"AKNAD1","NA","NA","NA","K21404//AT-hook-containing transcription factor","NP_689976.2//protein AKNAD1 [Homo sapiens]",4]
[6402,2442,0.03,0.1,1.73696559416621,0.53055993069131,"*",0.37379,"SELL","GO:0030667//secretory granule membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0002020//protease binding;GO:0050839//cell adhesion molecule binding;GO:0030246//carbohydrate binding;GO:0008201//heparin binding;GO:0043208//glycosphingolipid binding","GO:0033198//response to ATP;GO:0007155//cell adhesion;GO:0050900//leukocyte migration;GO:0043312//neutrophil degranulation;GO:0050776//regulation of immune response","K06495//selectin, lymphocyte","NP_000646.2//L-selectin precursor [Homo sapiens]",4]
[340393,1145,0.36,1.2,1.73696559416621,0.0452560753896882,"*",0.0189025,"TMEM249","GO:0016021//integral component of membrane","NA","NA","K10272//F-box and leucine-rich repeat protein 6","NP_001239331.1//transmembrane protein 249 isoform 1 [Homo sapiens];XP_008000253.1//PREDICTED: LOW QUALITY PROTEIN: transmembrane protein 249 [Chlorocebus sabaeus];NP_001239333.1//transmembrane protein 249 isoform 2 [Homo sapiens]","1//3;2//1"]
[27065,2418,0.03,0.1,1.73696559416621,0.530088908025568,"*",0.37379,"NSG1","GO:0030425//dendrite;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005770//late endosome;GO:0005737//cytoplasm;GO:0000139//Golgi membrane;GO:0005768//endosome;GO:0032588//trans-Golgi network membrane;GO:0098845//postsynaptic endosome;GO:0016021//integral component of membrane;GO:0016328//lateral plasma membrane;GO:0055037//recycling endosome;GO:0005769//early endosome;GO:0045211//postsynaptic membrane","GO:0005102//receptor binding;GO:0032051//clathrin light chain binding","GO:0099627//neurotransmitter receptor cycle;GO:0001881//receptor recycling;GO:0016197//endosomal transport;GO:0098814//spontaneous synaptic transmission;GO:1900271//regulation of long-term synaptic potentiation;GO:0001921//positive regulation of receptor recycling;GO:0007212//dopamine receptor signaling pathway;GO:0006915//apoptotic process;GO:0042982//amyloid precursor protein metabolic process;GO:0048268//clathrin coat assembly;GO:0099630//postsynaptic neurotransmitter receptor cycle;GO:0098887//neurotransmitter receptor transport, endosome to postsynaptic membrane","K10955//mucin-2;K15493//neuron-specific vesicular protein calcyon;K19582//lipid phosphate phosphatase-related protein type 3/4","EAW82430.1//DNA segment on chromosome 4 (unique) 234 expressed sequence, isoform CRA_a [Homo sapiens]","4;1//3"]
[134121,2460,0.03,0.1,1.73696559416621,0.529806695652174,"*",0.37379,"C5orf49","NA","NA","NA","K09291//nucleoprotein TPR","XP_003899537.1//uncharacterized protein C5orf49 homolog [Papio anubis]","2//1"]
[50619,2320,0.03,0.1,1.73696559416621,0.529712691625266,"*",0.37379,"DEF6","GO:0016020//membrane;GO:0005856//cytoskeleton;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0048471//perinuclear region of cytoplasm;GO:0030175//filopodium","NA","NA","K20072//switch-associated protein 70","XP_005553287.1//PREDICTED: differentially expressed in FDCP 6 homolog isoform X1 [Macaca fascicularis]","3//A2MP1"]
[391104,1014,0.16,0.53,1.7279204545632,0.303866758067263,"*",0.1787362,"VHLL","GO:0005929//cilium;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031462//Cul2-RING ubiquitin ligase complex;GO:0005730//nucleolus;GO:0030891//VCB complex","GO:0061630//ubiquitin protein ligase activity;GO:0032403//protein complex binding","GO:0006607//NLS-bearing protein import into nucleus;GO:0006582//melanin metabolic process;GO:0016567//protein ubiquitination;GO:0010629//negative regulation of gene expression;GO:0043534//blood vessel endothelial cell migration;GO:0003309//type B pancreatic cell differentiation;GO:0061073//ciliary body morphogenesis;GO:0010498//proteasomal protein catabolic process;GO:0045602//negative regulation of endothelial cell differentiation;GO:2001233//regulation of apoptotic signaling pathway;GO:0001525//angiogenesis;GO:0003310//pancreatic A cell differentiation;GO:1902072//negative regulation of hypoxia-inducible factor-1alpha signaling pathway;GO:0048877//homeostasis of number of retina cells;GO:0048069//eye pigmentation;GO:0061072//iris morphogenesis;GO:0030198//extracellular matrix organization;GO:0070244//negative regulation of thymocyte apoptotic process;GO:1903827//regulation of cellular protein localization;GO:0050679//positive regulation of epithelial cell proliferation","K03871//von Hippel-Lindau disease tumor supressor","NP_001004319.1//von Hippel-Lindau-like protein [Homo sapiens]","2//1"]
[10346,3099,0.1,0.33,1.72246602447109,0.0692726367428004,"*",0.0305686,"TRIM22","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0015030//Cajal body;GO:0005737//cytoplasm","GO:0003714//transcription corepressor activity;GO:0030674//protein binding, bridging;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0003700//DNA binding transcription factor activity;GO:0019901//protein kinase binding","GO:0060333//interferon-gamma-mediated signaling pathway;GO:0006355//regulation of transcription, DNA-templated;GO:0070206//protein trimerization;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0016567//protein ubiquitination;GO:0051607//defense response to virus;GO:0006351//transcription, DNA-templated;GO:0016032//viral process;GO:0010508//positive regulation of autophagy;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0032880//regulation of protein localization;GO:0006955//immune response;GO:0009615//response to virus","K11999//tripartite motif-containing protein 6/22/34","NP_001186502.1//E3 ubiquitin-protein ligase TRIM22 isoform 2 [Homo sapiens];NP_006065.2//E3 ubiquitin-protein ligase TRIM22 isoform 1 [Homo sapiens]","1//3;4"]
[6004,2432,0.07,0.23,1.71620703399941,0.203171859255792,"*",0.1086958,"RGS16","GO:0031224//intrinsic component of membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0005516//calmodulin binding;GO:0005096//GTPase activator activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0009968//negative regulation of signal transduction;GO:0007601//visual perception;GO:0043547//positive regulation of GTPase activity","K16449//regulator of G-protein signaling","NP_002919.3//regulator of G-protein signaling 16 [Homo sapiens]","3//A2MP1"]
[9021,2737,23.63,76.88,1.7019887067999,{"v":1.10460337792E-221,"d":"1.10E-221"},"Up",{"v":1.728752E-224,"d":"1.73E-224"},"SOCS3","GO:0005829//cytosol;GO:0005622//intracellular;GO:0005737//cytoplasm","GO:0004860//protein kinase inhibitor activity;GO:0001784//phosphotyrosine residue binding","GO:0043687//post-translational protein modification;GO:0007259//JAK-STAT cascade;GO:0040008//regulation of growth;GO:0016567//protein ubiquitination;GO:0060708//spongiotrophoblast differentiation;GO:0050728//negative regulation of inflammatory response;GO:0042532//negative regulation of tyrosine phosphorylation of STAT protein;GO:0001932//regulation of protein phosphorylation;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0060334//regulation of interferon-gamma-mediated signaling pathway;GO:0045597//positive regulation of cell differentiation;GO:0060674//placenta blood vessel development;GO:0046426//negative regulation of JAK-STAT cascade;GO:0043066//negative regulation of apoptotic process;GO:0060707//trophoblast giant cell differentiation;GO:0006469//negative regulation of protein kinase activity;GO:1990830//cellular response to leukemia inhibitory factor;GO:0060670//branching involved in labyrinthine layer morphogenesis;GO:0019221//cytokine-mediated signaling pathway","K04696//suppressor of cytokine signaling 3","OWK15009.1//SOCS3 [Cervus elaphus hippelaphus]",4]
[339145,1921,0.04,0.13,1.70043971814109,0.531315310553479,"*",0.37379,"FAM92B","GO:0005814//centriole;GO:0042995//cell projection","NA","GO:0030030//cell projection organization","K15421//secretion-regulating guanine nucleotide exchange factor;K02258//cytochrome c oxidase assembly protein subunit 11;K10837//O-phosphoseryl-tRNA(Sec) kinase [EC:2.7.1.164]","NP_940893.1//protein FAM92B [Homo sapiens]","2//1"]
[219285,6541,0.24,0.78,1.70043971814109,{"v":1.69130987600292E-6,"d":"1.69E-06"},"Up",{"v":2.9032e-07,"d":"2.90E-07"},"SAMD9L","GO:0005769//early endosome","NA","GO:0034058//endosomal vesicle fusion","NA","NP_689916.2//sterile alpha motif domain-containing protein 9-like [Homo sapiens]","4;1//3;2//1"]
[1470,694,0.12,0.39,1.70043971814109,0.530984567363273,"*",0.37379,"CST2","GO:0005615//extracellular space","GO:0002020//protease binding;GO:0004869//cysteine-type endopeptidase inhibitor activity","GO:2000117//negative regulation of cysteine-type endopeptidase activity;GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste","K13898//cystatin-SA","NP_001313.1//cystatin-SA precursor [Homo sapiens]","2//1"]
[6861,1823,0.27,0.87,1.68805599368526,0.0159973565265145,"*",0.00583552,"SYT5","GO:1990769//proximal neuron projection;GO:0030054//cell junction;GO:0048471//perinuclear region of cytoplasm;GO:0043025//neuronal cell body;GO:0055038//recycling endosome membrane;GO:0030672//synaptic vesicle membrane;GO:0031045//dense core granule;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005544//calcium-dependent phospholipid binding;GO:0030276//clathrin binding;GO:0005509//calcium ion binding;GO:0046982//protein heterodimerization activity;GO:0019905//syntaxin binding;GO:0001786//phosphatidylserine binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding","GO:0006906//vesicle fusion;GO:0048488//synaptic vesicle endocytosis;GO:0048791//calcium ion-regulated exocytosis of neurotransmitter;GO:0007268//chemical synaptic transmission;GO:0017158//regulation of calcium ion-dependent exocytosis","K19905//synaptotagmin-5","NP_003171.2//synaptotagmin-5 isoform 1 [Homo sapiens];XP_018871641.1//PREDICTED: synaptotagmin-5 isoform X3 [Gorilla gorilla gorilla]","1//3;2//1"]
[6543,5111,0.09,0.29,1.68805599368526,0.0239994062941847,"*",0.00922326,"SLC8A2","GO:0016323//basolateral plasma membrane;GO:0005887//integral component of plasma membrane;GO:0043197//dendritic spine;GO:0005886//plasma membrane;GO:0043204//perikaryon","GO:0046872//metal ion binding;GO:0005432//calcium:sodium antiporter activity;GO:0005516//calmodulin binding","GO:1903779//regulation of cardiac conduction;GO:0070588//calcium ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0007154//cell communication;GO:0007612//learning;GO:0006811//ion transport;GO:0007613//memory;GO:0060291//long-term synaptic potentiation;GO:0048172//regulation of short-term neuronal synaptic plasticity;GO:0006874//cellular calcium ion homeostasis","K05849//solute carrier family 8 (sodium/calcium exchanger)","XP_007995551.1//PREDICTED: sodium/calcium exchanger 2 isoform X1 [Chlorocebus sabaeus]","2//1"]
[1052,1269,24.11,77.66,1.68754005630595,{"v":1.02300214978723E-100,"d":"1.02E-100"},"Up",{"v":6.01992e-103,"d":"6.02E-103"},"CEBPD","GO:0005654//nucleoplasm","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0046982//protein heterodimerization activity;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0042803//protein homodimerization activity","GO:0045892//negative regulation of transcription, DNA-templated;GO:0002244//hematopoietic progenitor cell differentiation;GO:0045444//fat cell differentiation;GO:0048839//inner ear development;GO:0045669//positive regulation of osteoblast differentiation;GO:0006366//transcription from RNA polymerase II promoter","K10050//CCAAT/enhancer binding protein (C/EBP), delta","NP_005186.2//CCAAT/enhancer-binding protein delta [Homo sapiens]","3//A2MP1"]
[374897,1153,0.56,1.8,1.68449817427207,0.012579335201549,"*",0.00447372,"SBSN","GO:0031012//extracellular matrix;GO:0070062//extracellular exosome","NA","NA","K18626//trichohyalin","NP_001159506.1//suprabasin isoform 1 precursor [Homo sapiens];NP_001159507.1//suprabasin isoform 3 precursor [Homo sapiens];NP_940940.1//suprabasin isoform 2 precursor [Homo sapiens]","1//3;3//A2MP1"]
[10335,6280,0.05,0.16,1.67807190511264,0.0497644811954431,"*",0.0210566,"MRVI1","GO:0031095//platelet dense tubular network membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0016529//sarcoplasmic reticulum;GO:0048471//perinuclear region of cytoplasm","NA","NA","K12337//inositol 1,4,5-triphosphate receptor-associated cGMP kinase substrate","NP_569056.4//protein MRVI1 isoform d [Homo sapiens];BAH13268.1//unnamed protein product [Homo sapiens];NP_001193809.1//protein MRVI1 isoform e [Homo sapiens];NP_001092049.2//protein MRVI1 isoform a [Homo sapiens]","1//3;3//A2MP1;2//1"]
[401551,1275,0.06,0.19,1.66296501272243,0.52961872095086,"*",0.37379,"WDR38","NA","NA","NA","K19760//dynein assembly factor with WDR repeat domains 1;K18643//katanin p80 WD40 repeat-containing subunit B1;K16482//centriolar protein POC1","NP_001263305.1//WD repeat-containing protein 38 isoform 4 [Homo sapiens];XP_003918857.2//WD repeat-containing protein 38 isoform X4 [Papio anubis]","1//3;2//1"]
[51339,3766,0.12,0.38,1.66296501272243,0.0356518940958269,"*",0.0144402,"DACT1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0030877//beta-catenin destruction complex;GO:0030054//cell junction;GO:0045202//synapse;GO:0005737//cytoplasm","GO:0005080//protein kinase C binding;GO:0051018//protein kinase A binding;GO:0042826//histone deacetylase binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0070097//delta-catenin binding;GO:0008013//beta-catenin binding","GO:2000095//regulation of Wnt signaling pathway, planar cell polarity pathway;GO:0030178//negative regulation of Wnt signaling pathway;GO:0032092//positive regulation of protein binding;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0046329//negative regulation of JNK cascade;GO:0032091//negative regulation of protein binding;GO:0021915//neural tube development;GO:1903364//positive regulation of cellular protein catabolic process;GO:0035412//regulation of catenin import into nucleus;GO:0035413//positive regulation of catenin import into nucleus;GO:1904864//negative regulation of beta-catenin-TCF complex assembly;GO:0048619//embryonic hindgut morphogenesis;GO:0030177//positive regulation of Wnt signaling pathway;GO:0045732//positive regulation of protein catabolic process;GO:0031647//regulation of protein stability;GO:0016055//Wnt signaling pathway","K22154//dapper","XP_007985007.1//PREDICTED: dapper homolog 1 isoform X1 [Chlorocebus sabaeus];XP_007985008.1//PREDICTED: dapper homolog 1 isoform X2 [Chlorocebus sabaeus]","1//3;5"]
[924,1318,0.06,0.19,1.66296501272243,0.529243171423507,"*",0.37379,"CD7","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004872//receptor activity","GO:0042110//T cell activation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0006955//immune response;GO:0048873//homeostasis of number of cells within a tissue;GO:0002250//adaptive immune response","K06457//T-cell surface glycoprotein CD7","NP_006128.1//T-cell antigen CD7 precursor [Homo sapiens]",6]
[23034,6652,1.69,5.35,1.66251564500632,{"v":7.82957215255255e-37,"d":"7.83E-37"},"Up",{"v":1.632182e-38,"d":"1.63E-38"},"SAMD4A","GO:0030425//dendrite;GO:0005829//cytosol;GO:0001650//fibrillar center;GO:0030054//cell junction;GO:0045202//synapse;GO:0000932//P-body","GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0030371//translation repressor activity","GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0043488//regulation of mRNA stability;GO:0045727//positive regulation of translation","NA","NP_056404.4//protein Smaug homolog 1 isoform 1 [Homo sapiens];NP_001155048.2//protein Smaug homolog 1 isoform 2 [Homo sapiens];AAH21726.2//SAMD4A protein, partial [Homo sapiens]","1//3;2//1;5"]
[79713,1659,8.11,25.53,1.65441971818985,{"v":7.8405190051282e-43,"d":"7.84E-43"},"Up",{"v":1.339966e-44,"d":"1.34E-44"},"IGFLR1","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","NA","NA","NA","NP_078936.1//IGF-like family receptor 1 isoform a precursor [Homo sapiens];NP_001332935.1//IGF-like family receptor 1 isoform d precursor [Homo sapiens];XP_009230730.1//PREDICTED: IGF-like family receptor 1 isoform X1 [Pongo abelii];NP_001332932.1//IGF-like family receptor 1 isoform b precursor [Homo sapiens]","1//3;3//A2MP1"]
[3430,1255,19.74,62.11,1.65370357799031,{"v":1.10617668e-77,"d":"1.11E-77"},"Up",{"v":8.72532e-80,"d":"8.73E-80"},"IFI35","GO:0005634//nucleus;GO:0005829//cytosol","NA","GO:0060337//type I interferon signaling pathway","NA","NP_001317159.1//interferon-induced 35 kDa protein isoform 2 [Homo sapiens];NP_005524.2//interferon-induced 35 kDa protein isoform 1 [Homo sapiens]","1//3;4"]
[79025,1134,0.07,0.22,1.65207669657969,0.530654235691433,"*",0.37379,"FNDC11","GO:0070062//extracellular exosome","NA","NA","K19720//collagen, type III, alpha","XP_008960524.1//PREDICTED: uncharacterized protein C20orf195 homolog isoform X1 [Pan paniscus];XP_017736728.1//PREDICTED: uncharacterized protein C20orf195 homolog isoform X1 [Rhinopithecus bieti];XP_016883549.1//PREDICTED: uncharacterized protein C20orf195 isoform X1 [Homo sapiens]","1//3;3//A2MP1"]
[6795,1120,0.07,0.22,1.65207669657969,0.530135972653822,"*",0.37379,"AURKC","GO:0000793//condensed chromosome;GO:0051233//spindle midzone;GO:0000780//condensed nuclear chromosome, centromeric region;GO:0005737//cytoplasm;GO:0032133//chromosome passenger complex;GO:0030496//midbody;GO:0005819//spindle;GO:0031616//spindle pole centrosome;GO:0005876//spindle microtubule","GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0035174//histone serine kinase activity","GO:0032467//positive regulation of cytokinesis;GO:0048599//oocyte development;GO:0006468//protein phosphorylation;GO:0000910//cytokinesis;GO:0007283//spermatogenesis;GO:0051256//mitotic spindle midzone assembly;GO:0016570//histone modification;GO:0008608//attachment of spindle microtubules to kinetochore;GO:0051321//meiotic cell cycle;GO:0051255//spindle midzone assembly","K11480//aurora kinase C [EC:2.7.11.1]","XP_012355738.1//PREDICTED: aurora kinase C isoform X1 [Nomascus leucogenys];XP_005590555.1//PREDICTED: aurora kinase C [Macaca fascicularis];NP_001015879.1//aurora kinase C isoform 2 [Homo sapiens]","1//3;2//1"]
[2920,1234,15.52,48.53,1.64474830257707,{"v":4.04447636923077e-59,"d":"4.04E-59"},"Up",{"v":4.60808e-61,"d":"4.61E-61"},"CXCL2","GO:0005615//extracellular space;GO:0005576//extracellular region","GO:0045236//CXCR chemokine receptor binding;GO:0008009//chemokine activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0090023//positive regulation of neutrophil chemotaxis;GO:0042127//regulation of cell proliferation;GO:0070098//chemokine-mediated signaling pathway;GO:0032496//response to lipopolysaccharide;GO:0031640//killing of cells of other organism;GO:0002237//response to molecule of bacterial origin;GO:0006954//inflammatory response;GO:0006952//defense response;GO:0006955//immune response;GO:0006935//chemotaxis","K05505//C-X-C motif chemokine 1/2/3","XP_001092240.2//PREDICTED: uncharacterized protein LOC702067 [Macaca mulatta]","3//A2MP1"]
[56301,1962,0.08,0.25,1.64385618977472,0.303963809091877,"*",0.1787362,"SLC7A10","NA","NA","NA","K13782//solute carrier family 7 (L-type amino acid transporter), member 10","XP_019510086.1//PREDICTED: asc-type amino acid transporter 1 [Hipposideros armiger]","2//1"]
[1746,2308,0.69,2.15,1.63966839281129,{"v":1.18776606830514e-05,"d":"1.19E-05"},"Up",{"v":2.32958E-6,"d":"2.33E-06"},"DLX2","NA","NA","NA","K18488//homeobox protein DLX2","XP_003824309.1//PREDICTED: homeobox protein DLX-2 [Pan paniscus]","3//A2MP1"]
[9674,4531,0.3,0.93,1.63226821549951,{"v":3.64888608391608e-05,"d":"3.65E-05"},"Up",{"v":7.8396e-06,"d":"7.84E-06"},"KIAA0040","GO:0016021//integral component of membrane","NA","NA","NA","BAA05022.2//KIAA0040, partial [Homo sapiens]","1//3;2//1"]
[6991,805,0.1,0.31,1.63226821549951,0.529900733049343,"*",0.37379,"TCTE3","GO:0016020//membrane;GO:0005874//microtubule;GO:0030286//dynein complex;GO:0005737//cytoplasm","GO:0003774//motor activity","GO:0006810//transport","K22197//BRG1-associated factor 45A;K18631//tektin-4","XP_017750428.1//PREDICTED: tctex1 domain-containing protein 3 [Rhinopithecus bieti]","2//1"]
[50801,1694,0.1,0.31,1.63226821549951,0.203148088124488,"*",0.1086958,"KCNK4","NA","NA","NA","K04915//potassium channel subfamily K member 4","XP_012633391.1//potassium channel subfamily K member 4 isoform X1 [Microcebus murinus];AAI10328.1//KCNK4 protein, partial [Homo sapiens]","1//3;2//1"]
[10468,1959,0.66,2.04,1.62803122261304,1.02116558480326E-4,"Up",{"v":2.3557e-05,"d":"2.36E-05"},"FST","GO:0005576//extracellular region","GO:0043395//heparan sulfate proteoglycan binding;GO:0048185//activin binding;GO:0004871//signal transducer activity","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0002244//hematopoietic progenitor cell differentiation;GO:0051798//positive regulation of hair follicle development;GO:0032926//negative regulation of activin receptor signaling pathway","K04661//follistatin","EDL18378.1//follistatin, isoform CRA_a, partial [Mus musculus];NP_037541.1//follistatin isoform FST344 precursor [Homo sapiens]","3//A2MP1;2//1"]
[3078,1312,0.39,1.2,1.62148837674627,0.0240033162658847,"*",0.00922326,"CFHR1","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0072562//blood microparticle;GO:0043234//protein complex;GO:0005576//extracellular region","GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity","GO:0030449//regulation of complement activation;GO:0045919//positive regulation of cytolysis;GO:0006956//complement activation;GO:0032091//negative regulation of protein binding","K04004//complement factor H","NP_002104.2//complement factor H-related protein 1 precursor [Homo sapiens]","2//1"]
[200634,932,0.28,0.86,1.61890983264449,0.118382777233655,"*",0.0569014,"KRTCAP3","GO:0016021//integral component of membrane","NA","NA","NA","NP_776252.2//keratinocyte-associated protein 3 [Homo sapiens]","1//3;3//A2MP1"]
[30812,3049,0.29,0.89,1.61775243583883,0.00178090004776119,"*",0.000522876,"SOX8","GO:0005634//nucleus;GO:0044798//nuclear transcription factor complex;GO:0005737//cytoplasm","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0003677//DNA binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0046982//protein heterodimerization activity;GO:0008134//transcription factor binding","GO:0090184//positive regulation of kidney development;GO:0001649//osteoblast differentiation;GO:0046533//negative regulation of photoreceptor cell differentiation;GO:0060221//retinal rod cell differentiation;GO:0008584//male gonad development;GO:0072034//renal vesicle induction;GO:0045892//negative regulation of transcription, DNA-templated;GO:0007165//signal transduction;GO:0001755//neural crest cell migration;GO:0048709//oligodendrocyte differentiation;GO:0043066//negative regulation of apoptotic process;GO:0048469//cell maturation;GO:0035914//skeletal muscle cell differentiation;GO:0045662//negative regulation of myoblast differentiation;GO:0090190//positive regulation of branching involved in ureteric bud morphogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007422//peripheral nervous system development;GO:0033690//positive regulation of osteoblast proliferation;GO:0060041//retina development in camera-type eye;GO:0072197//ureter morphogenesis;GO:0060018//astrocyte fate commitment;GO:0007283//spermatogenesis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0072289//metanephric nephron tubule formation;GO:0045165//cell fate commitment;GO:0014015//positive regulation of gliogenesis;GO:0061138//morphogenesis of a branching epithelium;GO:0006351//transcription, DNA-templated;GO:0001701//in utero embryonic development;GO:0060612//adipose tissue development;GO:0060009//Sertoli cell development;GO:0048484//enteric nervous system development;GO:0010817//regulation of hormone levels;GO:0045444//fat cell differentiation","K09270//transcription factor SOX7/8/10/18 (SOX group E/F)","CAB75612.1//c394H11.1 (similar to SOX (SRY (sex determining region Y))) [Homo sapiens]",4]
[28951,4408,0.16,0.49,1.61470984411521,0.00749389215671642,"*",2.51454E-3,"TRIB2","GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0031434//mitogen-activated protein kinase kinase binding;GO:0005524//ATP binding;GO:0004860//protein kinase inhibitor activity;GO:0004672//protein kinase activity;GO:0031625//ubiquitin protein ligase binding;GO:0055106//ubiquitin-protein transferase regulator activity;GO:0008134//transcription factor binding","GO:0006469//negative regulation of protein kinase activity;GO:0045599//negative regulation of fat cell differentiation;GO:0045081//negative regulation of interleukin-10 biosynthetic process;GO:0043405//regulation of MAP kinase activity;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process","K08814//tribbles homolog 1/2","NP_067675.1//tribbles homolog 2 [Homo sapiens]","3//A2MP1"]
[3665,2009,2.15,6.57,1.61155671073287,{"v":2.72029816496465e-13,"d":"2.72E-13"},"Up",{"v":2.16786e-14,"d":"2.17E-14"},"IRF7","GO:0010008//endosome membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0000982//transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0060337//type I interferon signaling pathway;GO:0034124//regulation of MyD88-dependent toll-like receptor signaling pathway;GO:0032481//positive regulation of type I interferon production;GO:0016064//immunoglobulin mediated immune response;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0032479//regulation of type I interferon production;GO:0032607//interferon-alpha production;GO:0019043//establishment of viral latency;GO:2000110//negative regulation of macrophage apoptotic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006974//cellular response to DNA damage stimulus;GO:0045087//innate immune response;GO:0039530//MDA-5 signaling pathway;GO:0050776//regulation of immune response;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0032728//positive regulation of interferon-beta production;GO:0045351//type I interferon biosynthetic process;GO:0034127//regulation of MyD88-independent toll-like receptor signaling pathway;GO:0045655//regulation of monocyte differentiation;GO:0051607//defense response to virus;GO:0032727//positive regulation of interferon-alpha production;GO:0006351//transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter;GO:0002819//regulation of adaptive immune response;GO:0060340//positive regulation of type I interferon-mediated signaling pathway;GO:0032608//interferon-beta production;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0009615//response to virus","K09447//interferon regulatory factor 7","NP_004020.1//interferon regulatory factor 7 isoform b [Homo sapiens];NP_004022.2//interferon regulatory factor 7 isoform d [Homo sapiens];NP_001563.2//interferon regulatory factor 7 isoform a [Homo sapiens]","3//A2MP1;2//1"]
[100996693,815,0.2,0.61,1.60880924267552,0.303834421496222,"*",0.1787362,"LOC100996693","NA","NA","NA","K12567//titin [EC:2.7.11.1]","XP_010986680.1//PREDICTED: LOW QUALITY PROTEIN: CAVP-target protein [Camelus dromedarius]","1//3"]
[9241,1892,0.21,0.64,1.60768257722124,0.0605717868819374,"*",0.0263044,"NOG","GO:0005615//extracellular space;GO:0005576//extracellular region","GO:0019955//cytokine binding;GO:0042803//protein homodimerization activity","GO:0060044//negative regulation of cardiac muscle cell proliferation;GO:0060272//embryonic skeletal joint morphogenesis;GO:0001649//osteoblast differentiation;GO:0048712//negative regulation of astrocyte differentiation;GO:0060425//lung morphogenesis;GO:0060412//ventricular septum morphogenesis;GO:0061053//somite development;GO:0035019//somatic stem cell population maintenance;GO:0051216//cartilage development;GO:0003149//membranous septum morphogenesis;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0060825//fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation;GO:0061312//BMP signaling pathway involved in heart development;GO:0042474//middle ear morphogenesis;GO:0021533//cell differentiation in hindbrain;GO:0021983//pituitary gland development;GO:0045668//negative regulation of osteoblast differentiation;GO:0003203//endocardial cushion morphogenesis;GO:0003223//ventricular compact myocardium morphogenesis;GO:0048318//axial mesoderm development;GO:0001837//epithelial to mesenchymal transition;GO:0061384//heart trabecula morphogenesis;GO:0009953//dorsal/ventral pattern formation;GO:0030154//cell differentiation;GO:0008045//motor neuron axon guidance;GO:0030509//BMP signaling pathway;GO:0010628//positive regulation of gene expression;GO:0003151//outflow tract morphogenesis;GO:0055009//atrial cardiac muscle tissue morphogenesis;GO:0090190//positive regulation of branching involved in ureteric bud morphogenesis;GO:0060173//limb development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0061037//negative regulation of cartilage development;GO:0045596//negative regulation of cell differentiation;GO:0048706//embryonic skeletal system development;GO:0001843//neural tube closure;GO:0060394//negative regulation of pathway-restricted SMAD protein phosphorylation;GO:0001839//neural plate morphogenesis;GO:0060513//prostatic bud formation;GO:0007399//nervous system development;GO:0030514//negative regulation of BMP signaling pathway;GO:2000313//regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation;GO:0061626//pharyngeal arch artery morphogenesis;GO:0021510//spinal cord development;GO:0001706//endoderm formation;GO:0090193//positive regulation of glomerulus development;GO:0042733//embryonic digit morphogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0001707//mesoderm formation;GO:0060302//negative regulation of cytokine activity;GO:2001234//negative regulation of apoptotic signaling pathway;GO:0042060//wound healing;GO:0001701//in utero embryonic development;GO:0030336//negative regulation of cell migration;GO:0060676//ureteric bud formation;GO:1905006//negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation;GO:0048570//notochord morphogenesis;GO:0060325//face morphogenesis;GO:0001501//skeletal system development;GO:0050679//positive regulation of epithelial cell proliferation","K04658//noggin","XP_007176240.1//PREDICTED: noggin [Balaenoptera acutorostrata scammoni]",4]
[1381,782,0.21,0.64,1.60768257722124,0.304028544223192,"*",0.1787362,"CRABP1","GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0016918//retinal binding;GO:0001972//retinoic acid binding;GO:0005215//transporter activity;GO:0019841//retinol binding;GO:0005501//retinoid binding","GO:0007165//signal transduction;GO:0034653//retinoic acid catabolic process;GO:0007275//multicellular organism development","K17337//cellular retinoic acid-binding protein 1","OWK09030.1//hypothetical protein Celaphus_00015315 [Cervus elaphus hippelaphus]","2//1"]
[5148,1064,0.46,1.39,1.59537911666649,0.0356629181818182,"*",0.0144402,"PDE6G","GO:0097381//photoreceptor disc membrane;GO:0005886//plasma membrane","GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0004857//enzyme inhibitor activity;GO:0047555//3',5'-cyclic-GMP phosphodiesterase activity;GO:0030507//spectrin binding;GO:0030553//cGMP binding","GO:0016056//rhodopsin mediated signaling pathway;GO:0045745//positive regulation of G-protein coupled receptor protein signaling pathway;GO:0000187//activation of MAPK activity;GO:0007223//Wnt signaling pathway, calcium modulating pathway;GO:0007601//visual perception;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0045742//positive regulation of epidermal growth factor receptor signaling pathway","K13759//retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma","XP_006722005.1//PREDICTED: retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma isoform X3 [Homo sapiens]","3//A2MP1"]
[100125288,1997,0.48,1.45,1.59494658929378,0.00157657392330892,"*",0.000458148,"ZGLP1","GO:0005634//nucleus;GO:0005667//transcription factor complex","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0043565//sequence-specific DNA binding;GO:0008270//zinc ion binding;GO:0003700//DNA binding transcription factor activity;GO:0001085//RNA polymerase II transcription factor binding","GO:0048599//oocyte development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0030154//cell differentiation;GO:0007275//multicellular organism development;GO:0007283//spermatogenesis","K21630//GATA-type zinc finger protein 1","NP_001096637.1//GATA-type zinc finger protein 1 [Homo sapiens]","1//3"]
[8365,374,0.48,1.45,1.59494658929378,0.303931451862891,"*",0.1787362,"HIST1H4H","NA","NA","NA","K11254//histone H4","XP_003804484.2//PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein LOC100980546 [Pan paniscus]","3//A2MP1"]
[8789,1367,0.06,0.18,1.58496250072116,0.531599132834758,"*",0.37379,"FBP2","GO:0070062//extracellular exosome;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0042802//identical protein binding;GO:0042132//fructose 1,6-bisphosphate 1-phosphatase activity","GO:0005986//sucrose biosynthetic process;GO:0006002//fructose 6-phosphate metabolic process;GO:0006094//gluconeogenesis;GO:0006000//fructose metabolic process;GO:0005975//carbohydrate metabolic process;GO:0030388//fructose 1,6-bisphosphate metabolic process","K03841//fructose-1,6-bisphosphatase I [EC:3.1.3.11]","XP_012890385.1//PREDICTED: fructose-1,6-bisphosphatase isozyme 2 [Dipodomys ordii]","3//A2MP1"]
[319101,2323,0.01,0.03,1.58496250072116,0.655715815414987,"*",0.499032,"KRT73","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0045095//keratin filament","GO:0005198//structural molecule activity","NA","K07605//type II keratin, basic","XP_019275006.1//PREDICTED: keratin, type II cytoskeletal 73 isoform X1 [Panthera pardus]","2//1"]
[26266,2927,0.01,0.03,1.58496250072116,0.655607958549223,"*",0.499032,"SLC13A4","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0015382//sodium:sulfate symporter activity;GO:0005215//transporter activity","GO:0055085//transmembrane transport;GO:0008272//sulfate transport;GO:0006814//sodium ion transport;GO:0098656//anion transmembrane transport","K14444//solute carrier family 13 (sodium/sulfate cotransporter), member 1/4","NP_036582.2//solute carrier family 13 member 4 isoform 2 [Homo sapiens];NP_001305121.1//solute carrier family 13 member 4 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[2543,3014,0.01,0.03,1.58496250072116,0.655338471555409,"*",0.499032,"GAGE1","NA","NA","NA","K11447//histone demethylase [EC:1.14.11.-];K01064//wingless-type MMTV integration site family, member 9","NP_001035753.1//G antigen 1 [Homo sapiens]","2//1"]
[4481,2960,0.01,0.03,1.58496250072116,0.655230738780207,"*",0.499032,"MSR1","GO:0016021//integral component of membrane","GO:0005044//scavenger receptor activity","NA","K16628//collagen, type VII, alpha;K19721//collagen, type V/XI/XXIV/XXVII, alpha;K06558//macrophage scavenger receptor 1","XP_004940504.1//PREDICTED: collagen alpha-1(XIX) chain isoform X1 [Gallus gallus];XP_008061454.1//macrophage scavenger receptor types I and II isoform X1 [Carlito syrichta];XP_015714626.1//PREDICTED: collagen alpha-1(XIX) chain isoform X4 [Coturnix japonica]","3//A2MP1;2//1"]
[3270,2430,0.01,0.03,1.58496250072116,0.655123041420118,"*",0.499032,"HRC","GO:0005788//endoplasmic reticulum lumen;GO:0030018//Z disc;GO:0033018//sarcoplasmic reticulum lumen;GO:0033017//sarcoplasmic reticulum membrane","GO:0044325//ion channel binding;GO:0005509//calcium ion binding;GO:0051117//ATPase binding","GO:0043687//post-translational protein modification;GO:1901899//positive regulation of relaxation of cardiac muscle;GO:1901844//regulation of cell communication by electrical coupling involved in cardiac conduction;GO:0010460//positive regulation of heart rate;GO:0006936//muscle contraction;GO:0045823//positive regulation of heart contraction;GO:0033135//regulation of peptidyl-serine phosphorylation;GO:0002027//regulation of heart rate;GO:0051480//regulation of cytosolic calcium ion concentration;GO:1903169//regulation of calcium ion transmembrane transport;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0044267//cellular protein metabolic process;GO:0051481//negative regulation of cytosolic calcium ion concentration;GO:0060314//regulation of ryanodine-sensitive calcium-release channel activity;GO:0010881//regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion;GO:1902081//negative regulation of calcium ion import into sarcoplasmic reticulum","K19607//X-linked retinitis pigmentosa GTPase regulator","NP_002143.1//sarcoplasmic reticulum histidine-rich calcium-binding protein precursor [Homo sapiens]","2//1"]
[79781,3155,0.01,0.03,1.58496250072116,0.654961561745132,"*",0.499032,"IQCA1","NA","GO:0005524//ATP binding","NA","K13254//spastin [EC:3.6.4.3];K00665//fatty acid synthase, animal type [EC:2.3.1.85];K19607//X-linked retinitis pigmentosa GTPase regulator","NP_001257514.1//IQ and AAA domain-containing protein 1 isoform 3 [Homo sapiens];NP_079002.3//IQ and AAA domain-containing protein 1 isoform 1 [Homo sapiens];NP_001257513.1//IQ and AAA domain-containing protein 1 isoform 2 [Homo sapiens]","4;1//3"]
[51285,2606,0.01,0.03,1.58496250072116,0.654638841093865,"*",0.499032,"RASL12","GO:0016020//membrane","GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0007165//signal transduction","K07854//Ras-like protein family member 12","XP_011795786.1//PREDICTED: ras-like protein family member 12 isoform X1 [Colobus angolensis palliatus];XP_011795787.1//PREDICTED: ras-like protein family member 12 isoform X2 [Colobus angolensis palliatus]","1//3;3//A2MP1"]
[148345,2779,0.01,0.03,1.58496250072116,0.654585085235671,"*",0.499032,"C1orf127","NA","NA","NA","K10955//mucin-2;K22020//mucin-19","NP_001164225.1//uncharacterized protein C1orf127 precursor [Homo sapiens]","1//3"]
[5275,3124,0.01,0.03,1.58496250072116,0.654531338205107,"*",0.499032,"SERPINB13","GO:0070062//extracellular exosome;GO:0005654//nucleoplasm;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0043202//lysosomal lumen;GO:0005737//cytoplasm","GO:0002020//protease binding;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0004869//cysteine-type endopeptidase inhibitor activity","GO:0045616//regulation of keratinocyte differentiation;GO:0010951//negative regulation of endopeptidase activity;GO:0009411//response to UV;GO:0030162//regulation of proteolysis;GO:1902173//negative regulation of keratinocyte apoptotic process","K13963//serpin B","XP_004059557.2//PREDICTED: serpin B13 isoform X1 [Gorilla gorilla gorilla];NP_001335197.1//serpin B13 isoform 3 [Homo sapiens];XP_009432379.1//PREDICTED: serpin B13 isoform X1 [Pan troglodytes];XP_011524331.1//PREDICTED: serpin B13 isoform X1 [Homo sapiens]","1//3;3//A2MP1"]
[11174,7332,0.01,0.03,1.58496250072116,0.531362593218831,"*",0.37379,"ADAMTS6","GO:0005578//proteinaceous extracellular matrix","GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding","NA","K08621//a disintegrin and metalloproteinase with thrombospondin motifs 6 [EC:3.4.24.-]","NP_922932.2//A disintegrin and metalloproteinase with thrombospondin motifs 6 preproprotein [Homo sapiens]","3//A2MP1"]
[18,4814,0.01,0.03,1.58496250072116,0.395383067818489,"*",0.249274,"ABAT","NA","NA","NA","K13524//4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase [EC:2.6.1.19 2.6.1.22]","BAH11640.1//unnamed protein product [Homo sapiens];XP_007983271.1//PREDICTED: 4-aminobutyrate aminotransferase, mitochondrial isoform X1 [Chlorocebus sabaeus]","4;1//3;5"]
[11131,2754,0.01,0.03,1.58496250072116,0.653887061602822,"*",0.499032,"CAPN11","NA","NA","NA","K08580//calpain-11 [EC:3.4.22.-]","XP_016810152.1//PREDICTED: calpain-11 isoform X2 [Pan troglodytes]","3//A2MP1"]
[2793,930,0.09,0.27,1.58496250072116,0.531220770462633,"*",0.37379,"GNGT2","NA","NA","NA","K04549//guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2","XP_014422610.1//PREDICTED: guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 isoform X2 [Camelus ferus]","1//3;2//1"]
[399697,2695,0.01,0.03,1.58496250072116,0.653458248053119,"*",0.499032,"CTXN2","GO:0016021//integral component of membrane","NA","NA","NA","XP_005376763.1//PREDICTED: cortexin-2 [Chinchilla lanigera]","1//3"]
[83483,2319,0.01,0.03,1.58496250072116,0.652976504587156,"*",0.499032,"PLVAP","GO:0070062//extracellular exosome;GO:0009986//cell surface;GO:0005901//caveola;GO:0005622//intracellular;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm","GO:0042803//protein homodimerization activity","GO:0000165//MAPK cascade;GO:0002693//positive regulation of cellular extravasation;GO:0033209//tumor necrosis factor-mediated signaling pathway","K17309//plasmalemma vesicle-associated protein","NP_112600.1//plasmalemma vesicle-associated protein [Homo sapiens]","2//1"]
[644353,2951,0.01,0.03,1.58496250072116,0.652442066459322,"*",0.499032,"ZCCHC18","GO:0016607//nuclear speck","GO:0008270//zinc ion binding;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0003676//nucleic acid binding","GO:0030509//BMP signaling pathway","K12015//tripartite motif-containing protein 39 [EC:2.3.2.27]","NP_001137450.1//zinc finger CCHC domain-containing protein 18 [Homo sapiens]","2//1"]
[256006,6036,0.01,0.03,1.58496250072116,0.735367718863049,"*",0.623548,"ANKRD31","NA","NA","NA","K09663//beta-1,6-N-acetylglucosaminyltransferase 4 [EC:2.4.1.-];K21436//ankyrin repeat domain-containing protein 11/12","NP_001157915.1//putative ankyrin repeat domain-containing protein 31 [Homo sapiens]","1//3"]
[9535,668,0.15,0.45,1.58496250072116,0.531079023392333,"*",0.37379,"GMFG","GO:0034774//secretory granule lumen;GO:0005622//intracellular;GO:1904813//ficolin-1-rich granule lumen;GO:0005576//extracellular region","GO:0003779//actin binding;GO:0008083//growth factor activity;GO:0004860//protein kinase inhibitor activity;GO:0008047//enzyme activator activity;GO:0071933//Arp2/3 complex binding","GO:0034316//negative regulation of Arp2/3 complex-mediated actin nucleation;GO:0071846//actin filament debranching;GO:0006468//protein phosphorylation;GO:0043312//neutrophil degranulation;GO:2000249//regulation of actin cytoskeleton reorganization","K20368//protein cornichon","XP_012630098.1//glia maturation factor gamma [Microcebus murinus];XP_008580296.1//PREDICTED: glia maturation factor gamma isoform X3 [Galeopterus variegatus]","1//3;3//A2MP1"]
[5017,3039,0.01,0.03,1.58496250072116,0.651588782736636,"*",0.499032,"OVOL1","GO:0005634//nucleus","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0007498//mesoderm development;GO:0043588//skin development;GO:0001822//kidney development;GO:0006351//transcription, DNA-templated;GO:0007283//spermatogenesis;GO:1901994//negative regulation of meiotic cell cycle phase transition;GO:0008544//epidermis development;GO:2000647//negative regulation of stem cell proliferation;GO:0051729//germline cell cycle switching, mitotic to meiotic cell cycle","K09216//ovo","XP_002821563.3//PREDICTED: putative transcription factor Ovo-like 1 [Pongo abelii]","3//A2MP1"]
[4018,6489,0.01,0.03,1.58496250072116,0.735259153465712,"*",0.623548,"LPA","NA","NA","NA","K09644//apolipoprotein(a) [EC:3.4.21.-]","NP_005568.2//apolipoprotein(a) precursor [Homo sapiens]","2//1"]
[8796,3180,0.01,0.03,1.58496250072116,0.651269376470588,"*",0.499032,"SCEL","GO:0070062//extracellular exosome;GO:0001533//cornified envelope;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm","GO:0046872//metal ion binding","GO:0009612//response to mechanical stimulus;GO:0008544//epidermis development;GO:0030216//keratinocyte differentiation;GO:0009790//embryo development;GO:0090263//positive regulation of canonical Wnt signaling pathway","K06084//F-box protein 20;K16580//SLAIN motif-containing protein 1/2","NP_001154178.1//sciellin isoform 3 [Homo sapiens];NP_659001.2//sciellin isoform 1 [Homo sapiens];NP_003834.3//sciellin isoform 2 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[6196,5692,0.01,0.03,1.58496250072116,0.394521240067373,"*",0.249274,"RPS6KA2","GO:0005840//ribosome;GO:0005634//nucleus;GO:0005819//spindle;GO:0005737//cytoplasm","GO:0000287//magnesium ion binding;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0004711//ribosomal protein S6 kinase activity","GO:0002035//brain renin-angiotensin system;GO:0045786//negative regulation of cell cycle;GO:0010659//cardiac muscle cell apoptotic process;GO:0007507//heart development;GO:0006468//protein phosphorylation;GO:0001556//oocyte maturation;GO:0035556//intracellular signal transduction;GO:0010628//positive regulation of gene expression;GO:0070613//regulation of protein processing;GO:0043065//positive regulation of apoptotic process;GO:0071322//cellular response to carbohydrate stimulus;GO:0045835//negative regulation of meiotic nuclear division;GO:0018105//peptidyl-serine phosphorylation;GO:0060047//heart contraction;GO:0008285//negative regulation of cell proliferation","K04373//ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]","NP_001179407.1//ribosomal protein S6 kinase alpha-2 [Bos taurus];DAA25952.1//TPA: ribosomal protein S6 kinase, 90kDa, polypeptide 2 isoform 2 [Bos taurus];XP_017363792.1//PREDICTED: ribosomal protein S6 kinase alpha-2 isoform X1 [Cebus capucinus imitator]","1//3;2//1;5"]
[114569,2831,0.01,0.03,1.58496250072116,0.650525311571732,"*",0.499032,"MAL2","GO:0070062//extracellular exosome;GO:0012505//endomembrane system;GO:0045121//membrane raft;GO:0016324//apical plasma membrane;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm","GO:0019911//structural constituent of myelin sheath","GO:0042552//myelination;GO:0001766//membrane raft polarization;GO:0008104//protein localization;GO:0045056//transcytosis","NA","NP_443118.1//protein MAL2 [Homo sapiens]","2//1"]
[8404,2932,0.01,0.03,1.58496250072116,0.650472229130967,"*",0.499032,"SPARCL1","GO:0070062//extracellular exosome;GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix","GO:0005518//collagen binding;GO:0005509//calcium ion binding;GO:0050840//extracellular matrix binding","GO:0043687//post-translational protein modification;GO:0044267//cellular protein metabolic process;GO:0007165//signal transduction;GO:0048856//anatomical structure development","K10402//kinesin family member 20;K19607//X-linked retinitis pigmentosa GTPase regulator","NP_001121782.1//SPARC-like protein 1 isoform 1 precursor [Homo sapiens]","1//3;2//1;5"]
[4593,2466,0.01,0.03,1.58496250072116,0.65041915535248,"*",0.499032,"MUSK","GO:0005887//integral component of plasma membrane;GO:0031594//neuromuscular junction;GO:0030054//cell junction;GO:0043235//receptor complex;GO:0045211//postsynaptic membrane","GO:0004713//protein tyrosine kinase activity;GO:0046872//metal ion binding;GO:0005524//ATP binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity","GO:0007528//neuromuscular junction development;GO:0030154//cell differentiation;GO:2000541//positive regulation of protein geranylgeranylation;GO:0010628//positive regulation of gene expression;GO:0046777//protein autophosphorylation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007613//memory;GO:0007275//multicellular organism development;GO:0008582//regulation of synaptic growth at neuromuscular junction;GO:0001934//positive regulation of protein phosphorylation;GO:0071340//skeletal muscle acetylcholine-gated channel clustering","K05129//muscle, skeletal, receptor tyrosine kinase [EC:2.7.10.1]","NP_001159752.1//muscle, skeletal receptor tyrosine-protein kinase isoform 2 [Homo sapiens];NP_001159753.1//muscle, skeletal receptor tyrosine-protein kinase isoform 3 [Homo sapiens];NP_005583.1//muscle, skeletal receptor tyrosine-protein kinase isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[1006,4962,0.01,0.03,1.58496250072116,0.394130740968029,"*",0.249274,"CDH8","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005509//calcium ion binding","GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules","K06800//cadherin 8, type 2","XP_019610595.1//PREDICTED: cadherin-8 isoform X1 [Rhinolophus sinicus]",4]
[284898,2407,0.01,0.03,1.58496250072116,0.650259985969492,"*",0.499032,"LOC284898","NA","NA","NA","NA","NP_001305258.1//uncharacterized protein LOC284898 precursor [Homo sapiens]","1//3"]
[5317,5384,0.01,0.03,1.58496250072116,0.734987880165289,"*",0.623548,"PKP1","GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0101003//ficolin-1-rich granule membrane;GO:0001533//cornified envelope;GO:0005882//intermediate filament;GO:0005886//plasma membrane;GO:1990124//messenger ribonucleoprotein complex;GO:0030057//desmosome","GO:0030280//structural constituent of epidermis;GO:0004871//signal transducer activity;GO:0019215//intermediate filament binding;GO:0005521//lamin binding","GO:0045110//intermediate filament bundle assembly;GO:1902373//negative regulation of mRNA catabolic process;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0043312//neutrophil degranulation;GO:0031424//keratinization;GO:0010628//positive regulation of gene expression;GO:0070268//cornification","K10387//plakophilin 1","NP_000290.2//plakophilin-1 isoform 1b [Homo sapiens];NP_001005337.1//plakophilin-1 isoform 1a [Homo sapiens]","3//A2MP1;2//1"]
[93034,2898,0.01,0.03,1.58496250072116,0.649994876712329,"*",0.499032,"NT5C1B","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0000287//magnesium ion binding;GO:0008253//5'-nucleotidase activity;GO:0000166//nucleotide binding","GO:0006195//purine nucleotide catabolic process;GO:0009117//nucleotide metabolic process","K01081//5'-nucleotidase [EC:3.1.3.5]","AAK39108.1//autoimmune infertility-related protein, partial [Homo sapiens];NP_001186016.1//cytosolic 5'-nucleotidase 1B isoform 4 [Homo sapiens];NP_001186017.1//cytosolic 5'-nucleotidase 1B isoform 5 [Homo sapiens];NP_001186015.1//cytosolic 5'-nucleotidase 1B isoform 3 [Homo sapiens];NP_001002006.1//cytosolic 5'-nucleotidase 1B isoform 1 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[51209,3802,0.02,0.06,1.58496250072116,0.530937351947359,"*",0.37379,"RAB9B","NA","NA","NA","K07900//Ras-related protein Rab-9B","XP_008508240.1//PREDICTED: ras-related protein Rab-9B isoform X1 [Equus przewalskii]","3//A2MP1"]
[283777,3298,0.01,0.03,1.58496250072116,0.649888893526822,"*",0.499032,"FAM169B","NA","NA","NA","K19464//pleckstrin homology domain-containing family G member 5;K12869//crooked neck","XP_009428176.2//PREDICTED: protein FAM169B [Pan troglodytes]","2//1"]
[283685,3151,0.01,0.03,1.58496250072116,0.649518224395013,"*",0.499032,"GOLGA6L2","GO:0005794//Golgi apparatus","NA","NA","K20358//golgin subfamily A member 2","NP_001291317.1//golgin subfamily A member 6-like protein 2 [Homo sapiens]","1//3"]
[645121,2594,0.03,0.09,1.58496250072116,0.530842946301565,"*",0.37379,"CCNI2","NA","NA","NA","K16939//septin 6/8/11","NP_001034869.1//cyclin-I2 isoform 2 [Homo sapiens];NP_001274182.1//cyclin-I2 isoform 3 [Homo sapiens];NP_001274181.1//cyclin-I2 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[57556,6950,0.01,0.03,1.58496250072116,0.226669876740741,"*",0.1245166,"SEMA6A","GO:0030424//axon;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane","GO:0030215//semaphorin receptor binding;GO:0004888//transmembrane signaling receptor activity","GO:0007399//nervous system development;GO:0007166//cell surface receptor signaling pathway;GO:0006915//apoptotic process;GO:0009887//animal organ morphogenesis;GO:0051642//centrosome localization;GO:0001764//neuron migration;GO:0007010//cytoskeleton organization;GO:0071526//semaphorin-plexin signaling pathway;GO:0007411//axon guidance;GO:2001224//positive regulation of neuron migration","K06842//semaphorin 6","NP_065847.1//semaphorin-6A isoform 2 precursor [Homo sapiens];NP_001287709.1//semaphorin-6A isoform 1 precursor [Homo sapiens]","1//3;4"]
[115350,2989,0.01,0.03,1.58496250072116,0.648883774358974,"*",0.499032,"FCRL1","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","NA","NA","K06727//Fc receptor-like protein","NP_001152870.1//Fc receptor-like protein 1 isoform 3 precursor [Homo sapiens];NP_001152869.1//Fc receptor-like protein 1 isoform 2 precursor [Homo sapiens];NP_443170.1//Fc receptor-like protein 1 isoform 1 precursor [Homo sapiens]","1//3;4"]
[134111,6129,0.01,0.03,1.58496250072116,0.734716806963192,"*",0.623548,"UBE2QL1","GO:0005634//nucleus;GO:0005886//plasma membrane","GO:0005524//ATP binding;GO:0061631//ubiquitin conjugating enzyme activity","NA","K10582//ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]","XP_007959358.1//PREDICTED: ubiquitin-conjugating enzyme E2Q-like protein 1 [Chlorocebus sabaeus]","2//1"]
[151126,2645,0.01,0.03,1.58496250072116,0.64872535546875,"*",0.499032,"ZNF385B","GO:0001650//fibrillar center","GO:0002039//p53 binding;GO:0008270//zinc ion binding;GO:0003676//nucleic acid binding","GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator","K10137//zinc finger, matrin type 3","NP_001339738.1//zinc finger protein 385B isoform 4 [Homo sapiens];NP_001339745.1//zinc finger protein 385B isoform 8 [Homo sapiens];NP_001339740.1//zinc finger protein 385B isoform 6 [Homo sapiens];XP_012641285.1//zinc finger protein 385B isoform X4 [Microcebus murinus];XP_021570045.1//zinc finger protein 385B isoform X4 [Carlito syrichta];NP_001339741.1//zinc finger protein 385B isoform 7 [Homo sapiens];NP_689733.4//zinc finger protein 385B isoform 1 [Homo sapiens];NP_001339739.1//zinc finger protein 385B isoform 5 [Homo sapiens]","1//3;2//1;5"]
[140893,2853,0.01,0.03,1.58496250072116,0.648619785842148,"*",0.499032,"RBBP8NL","GO:0005615//extracellular space","NA","NA","K20773//DNA endonuclease RBBP8 [EC:3.1.-.-]","XP_016792691.1//PREDICTED: RBBP8 N-terminal-like protein isoform X1 [Pan troglodytes]","2//1"]
[84911,2819,0.01,0.03,1.58496250072116,0.648461495810624,"*",0.499032,"ZNF382","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_020727394.1//zinc finger protein 382 isoform X4 [Odocoileus virginianus texanus]","4;1//3"]
[60494,2518,0.01,0.03,1.58496250072116,0.648408749633968,"*",0.499032,"CCDC81","GO:0005813//centrosome;GO:0005737//cytoplasm","GO:0003677//DNA binding","NA","K14165//atypical dual specificity phosphatase [EC:3.1.3.16 3.1.3.48];K12875//apoptotic chromatin condensation inducer in the nucleus;K04257//olfactory receptor;K18626//trichohyalin","NP_001149946.1//coiled-coil domain-containing protein 81 isoform 1 [Homo sapiens];NP_068599.3//coiled-coil domain-containing protein 81 isoform 2 [Homo sapiens]","1//3;4"]
[1008,2950,0.01,0.03,1.58496250072116,0.648250562576238,"*",0.499032,"CDH10","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005509//calcium ion binding","GO:0098609//cell-cell adhesion;GO:0034332//adherens junction organization;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules","K06802//cadherin 10, type 2, T2-cadherin","NP_006718.2//cadherin-10 isoform 1 preproprotein [Homo sapiens];XP_007534593.1//PREDICTED: cadherin-10 isoform X1 [Erinaceus europaeus];XP_016048640.1//PREDICTED: cadherin-10 isoform X2 [Erinaceus europaeus]","1//3;4"]
[57540,5231,0.01,0.03,1.58496250072116,0.393741014140216,"*",0.249274,"DISP3","GO:0031965//nuclear membrane;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005737//cytoplasm;GO:0030659//cytoplasmic vesicle membrane","NA","GO:2000179//positive regulation of neural precursor cell proliferation;GO:0045665//negative regulation of neuron differentiation;GO:0008203//cholesterol metabolic process;GO:0042632//cholesterol homeostasis;GO:0007224//smoothened signaling pathway;GO:0045834//positive regulation of lipid metabolic process;GO:0032368//regulation of lipid transport","K10955//mucin-2;K18730//PERQ amino acid-rich with GYF domain-containing protein","NP_065831.1//protein dispatched homolog 3 [Homo sapiens]","1//3"]
[166979,2858,0.01,0.03,1.58496250072116,0.647723829365402,"*",0.499032,"CDC20B","NA","GO:0097027//ubiquitin-protein transferase activator activity;GO:0010997//anaphase-promoting complex binding","GO:1904668//positive regulation of ubiquitin protein ligase activity","K03363//cell division cycle 20, cofactor of APC complex","NP_689836.2//cell division cycle protein 20 homolog B isoform 1 [Homo sapiens];NP_001163873.1//cell division cycle protein 20 homolog B isoform 3 [Homo sapiens];NP_001139206.2//cell division cycle protein 20 homolog B isoform 2 [Homo sapiens]","1//3;2//1"]
[140689,3107,0.01,0.03,1.58496250072116,0.647671203119922,"*",0.499032,"CBLN4","GO:0005615//extracellular space;GO:0030054//cell junction;GO:0045202//synapse","NA","GO:0009306//protein secretion","K18744//caprin-2","XP_015335073.1//PREDICTED: cerebellin-4 [Marmota marmota marmota]",5]
[6716,2446,0.01,0.03,1.58496250072116,0.647513375680286,"*",0.499032,"SRD5A2","GO:0016021//integral component of membrane;GO:0005737//cytoplasm","GO:0030283//testosterone dehydrogenase [NAD(P)] activity;GO:0009917//sterol 5-alpha reductase activity;GO:0003865//3-oxo-5-alpha-steroid 4-dehydrogenase activity","GO:0061370//testosterone biosynthetic process;GO:0030539//male genitalia development;GO:0008584//male gonad development;GO:0006702//androgen biosynthetic process","K12344//3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:1.3.1.22]","XP_003262754.2//PREDICTED: 3-oxo-5-alpha-steroid 4-dehydrogenase 2 [Nomascus leucogenys]","3//A2MP1"]
[9081,1238,0.01,0.03,1.58496250072116,0.999783057762185,"*",0.999032,"PRY","NA","NA","NA","K07899//Ras-related protein Rab-9A","NP_004667.2//PTPN13-like protein, Y-linked [Homo sapiens]","2//1"]
[2769,2311,0.01,0.03,1.58496250072116,0.647303058708892,"*",0.499032,"GNA15","GO:0005834//heterotrimeric G-protein complex;GO:0005886//plasma membrane","GO:0031683//G-protein beta/gamma-subunit complex binding;GO:0046872//metal ion binding;GO:0001664//G-protein coupled receptor binding;GO:0004871//signal transducer activity;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0007202//activation of phospholipase C activity;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0030168//platelet activation;GO:0060158//phospholipase C-activating dopamine receptor signaling pathway;GO:0007207//phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway","K04637//guanine nucleotide-binding protein subunit alpha-15","NP_002059.3//guanine nucleotide-binding protein subunit alpha-15 [Homo sapiens]","3//A2MP1"]
[94240,3194,0.01,0.03,1.58496250072116,0.647250500811952,"*",0.499032,"EPSTI1","NA","NA","NA","K18730//PERQ amino acid-rich with GYF domain-containing protein;K20045//intersectin","NP_001317472.1//epithelial-stromal interaction protein 1 isoform 3 [Homo sapiens];NP_001002264.1//epithelial-stromal interaction protein 1 isoform 1 [Homo sapiens];NP_150280.1//epithelial-stromal interaction protein 1 isoform 2 [Homo sapiens]","4;1//3;3//A2MP1"]
[94026,3170,0.01,0.03,1.58496250072116,0.647092878318045,"*",0.499032,"POM121L2","GO:0005622//intracellular","GO:0005487//nucleocytoplasmic transporter activity;GO:0017056//structural constituent of nuclear pore;GO:0008139//nuclear localization sequence binding","GO:0006606//protein import into nucleus;GO:0006405//RNA export from nucleus","K14316//nuclear pore complex protein Nup121","NP_258443.2//POM121-like protein 2 [Homo sapiens]","3//A2MP1"]
[23349,5850,0.01,0.03,1.58496250072116,0.393274358123457,"*",0.249274,"PHF24","NA","GO:0005509//calcium ion binding","GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0007214//gamma-aminobutyric acid signaling pathway;GO:0050966//detection of mechanical stimulus involved in sensory perception of pain;GO:0032228//regulation of synaptic transmission, GABAergic","K09291//nucleoprotein TPR;K10367//formin 1;K20638//Rho GTPase-activating protein 17","XP_011516129.1//PREDICTED: PHD finger protein 24 isoform X1 [Homo sapiens];XP_004048026.2//PREDICTED: PHD finger protein 24 isoform X2 [Gorilla gorilla gorilla]","1//3;2//1"]
[3818,2234,0.01,0.03,1.58496250072116,0.646463155299651,"*",0.499032,"KLKB1","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0004252//serine-type endopeptidase activity","GO:0042730//fibrinolysis;GO:0002542//Factor XII activation;GO:0022617//extracellular matrix disassembly;GO:0006508//proteolysis;GO:0051919//positive regulation of fibrinolysis;GO:0007597//blood coagulation, intrinsic pathway;GO:0031638//zymogen activation;GO:0031639//plasminogen activation","K01324//plasma kallikrein [EC:3.4.21.34]","NP_000883.2//plasma kallikrein isoform 1 preproprotein [Homo sapiens];NP_001305325.1//plasma kallikrein isoform 3 precursor [Homo sapiens];XP_016863672.1//PREDICTED: plasma kallikrein isoform X3 [Homo sapiens]","4;1//3"]
[7173,2930,0.01,0.03,1.58496250072116,0.64630591600454,"*",0.499032,"TPO","GO:0005615//extracellular space;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005886//plasma membrane","GO:0020037//heme binding;GO:0004601//peroxidase activity;GO:0005509//calcium ion binding;GO:0004447//iodide peroxidase activity","GO:0006979//response to oxidative stress;GO:0042446//hormone biosynthetic process;GO:0035162//embryonic hemopoiesis;GO:0006590//thyroid hormone generation;GO:0042744//hydrogen peroxide catabolic process","K00431//thyroid peroxidase [EC:1.11.1.8]","NP_000538.3//thyroid peroxidase isoform a precursor [Homo sapiens];NP_783650.1//thyroid peroxidase isoform b precursor [Homo sapiens];NP_783653.1//thyroid peroxidase isoform e precursor [Homo sapiens];NP_783652.1//thyroid peroxidase isoform d precursor [Homo sapiens]","1//3;3//A2MP1;5"]
[55170,2665,0.01,0.03,1.58496250072116,0.646148753181487,"*",0.499032,"PRMT6","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol","GO:0042393//histone binding;GO:0035242//protein-arginine omega-N asymmetric methyltransferase activity;GO:0008469//histone-arginine N-methyltransferase activity;GO:0042054//histone methyltransferase activity;GO:0016274//protein-arginine N-methyltransferase activity;GO:0044020//histone methyltransferase activity (H4-R3 specific);GO:0070612//histone methyltransferase activity (H2A-R3 specific);GO:0003682//chromatin binding;GO:0035241//protein-arginine omega-N monomethyltransferase activity;GO:0070611//histone methyltransferase activity (H3-R2 specific)","GO:0045892//negative regulation of transcription, DNA-templated;GO:0016571//histone methylation;GO:0006284//base-excision repair;GO:0006355//regulation of transcription, DNA-templated;GO:0034970//histone H3-R2 methylation;GO:0006351//transcription, DNA-templated;GO:0016032//viral process;GO:0045652//regulation of megakaryocyte differentiation;GO:0016049//cell growth;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0090398//cellular senescence;GO:0019919//peptidyl-arginine methylation, to asymmetrical-dimethyl arginine","K11437//type I protein arginine methyltransferase [EC:2.1.1.319]","XP_017830473.1//PREDICTED: protein arginine N-methyltransferase 6 [Callithrix jacchus]","2//1"]
[78997,2585,0.01,0.03,1.58496250072116,0.646044020423049,"*",0.499032,"GDAP1L1","GO:0016021//integral component of membrane;GO:0005737//cytoplasm","GO:0004364//glutathione transferase activity","GO:0006749//glutathione metabolic process","K22077//ganglioside-induced differentiation-associated protein 1","NP_001243668.1//ganglioside-induced differentiation-associated protein 1-like 1 isoform 4 [Homo sapiens];NP_001243669.1//ganglioside-induced differentiation-associated protein 1-like 1 isoform 5 [Homo sapiens];NP_001243666.1//ganglioside-induced differentiation-associated protein 1-like 1 isoform 1 [Homo sapiens];NP_076939.3//ganglioside-induced differentiation-associated protein 1-like 1 isoform 2 [Homo sapiens]","4;1//3"]
[81492,2484,0.01,0.03,1.58496250072116,0.645991666774716,"*",0.499032,"RSPH6A","NA","NA","NA","K06100//symplekin;K19756//radial spoke head protein 4A","XP_011935961.1//PREDICTED: radial spoke head protein 6 homolog A isoform X1 [Cercocebus atys]","3//A2MP1"]
[695,2767,0.01,0.03,1.58496250072116,0.64583465672851,"*",0.499032,"BTK","GO:0005634//nucleus;GO:0031410//cytoplasmic vesicle;GO:0005622//intracellular;GO:0042629//mast cell granule;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0045121//membrane raft;GO:0005829//cytosol;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0005886//plasma membrane","GO:0004713//protein tyrosine kinase activity;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0046872//metal ion binding;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0005102//receptor binding","GO:0001812//positive regulation of type I hypersensitivity;GO:0038083//peptidyl-tyrosine autophosphorylation;GO:0034614//cellular response to reactive oxygen species;GO:0097190//apoptotic signaling pathway;GO:0042127//regulation of cell proliferation;GO:0035556//intracellular signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0071226//cellular response to molecule of fungal origin;GO:0001818//negative regulation of cytokine production;GO:0045087//innate immune response;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0050853//B cell receptor signaling pathway;GO:0098761//cellular response to interleukin-7;GO:0007498//mesoderm development;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0002553//histamine secretion by mast cell;GO:0006468//protein phosphorylation;GO:0019722//calcium-mediated signaling;GO:0006351//transcription, DNA-templated;GO:0045579//positive regulation of B cell differentiation;GO:0001805//positive regulation of type III hypersensitivity;GO:0002250//adaptive immune response;GO:0048469//cell maturation;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0002721//regulation of B cell cytokine production;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0002344//B cell affinity maturation;GO:0002902//regulation of B cell apoptotic process;GO:0030889//negative regulation of B cell proliferation;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0042113//B cell activation","K07370//Bruton agammaglobulinemia tyrosine kinase [EC:2.7.10.2]","NP_001274273.1//tyrosine-protein kinase BTK isoform 3 [Homo sapiens];NP_001274274.1//tyrosine-protein kinase BTK isoform 2 [Homo sapiens];XP_011820173.1//PREDICTED: tyrosine-protein kinase BTK isoform X1 [Mandrillus leucophaeus]","1//3;2//1"]
[11063,2177,0.01,0.03,1.58496250072116,0.645782337005833,"*",0.499032,"SOX30","GO:0005634//nucleus","GO:0003677//DNA binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding","GO:0031960//response to corticosteroid;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0007283//spermatogenesis","K09271//transcription factor SOX15/30","NP_848511.1//transcription factor SOX-30 isoform a [Homo sapiens];NP_001295094.1//transcription factor SOX-30 isoform c [Homo sapiens];NP_008948.1//transcription factor SOX-30 isoform b [Homo sapiens]","1//3;2//1"]
[163059,2343,0.01,0.03,1.58496250072116,0.645730025759417,"*",0.499032,"ZNF433","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","NP_001295277.1//zinc finger protein 433 isoform 3 [Homo sapiens];NP_001073880.1//zinc finger protein 433 isoform 1 [Homo sapiens]","1//3;2//1"]
[9718,3162,0.01,0.03,1.58496250072116,0.645155160893493,"*",0.499032,"ECE2","GO:0016021//integral component of membrane","GO:0004222//metalloendopeptidase activity","GO:0016486//peptide hormone processing","K01415//endothelin-converting enzyme [EC:3.4.24.71]","XP_021586018.1//endothelin-converting enzyme 2 isoform X1 [Ictidomys tridecemlineatus];XP_005331107.1//endothelin-converting enzyme 2 isoform X3 [Ictidomys tridecemlineatus];XP_005331106.1//endothelin-converting enzyme 2 isoform X2 [Ictidomys tridecemlineatus]","1//3;2//1"]
[4129,2611,0.03,0.09,1.58496250072116,0.529947764267329,"*",0.37379,"MAOB","GO:0016021//integral component of membrane","GO:0016491//oxidoreductase activity","NA","K00274//monoamine oxidase [EC:1.4.3.4]","XP_003808422.1//PREDICTED: amine oxidase [flavin-containing] B [Pan paniscus]",4]
[4684,5977,0.01,0.03,1.58496250072116,0.392653868060349,"*",0.249274,"NCAM1","GO:0016020//membrane;GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0009897//external side of plasma membrane;GO:0031225//anchored component of membrane;GO:0000139//Golgi membrane;GO:0009986//cell surface;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0042802//identical protein binding;GO:0001618//virus receptor activity","GO:0060333//interferon-gamma-mediated signaling pathway;GO:0000165//MAPK cascade;GO:0007155//cell adhesion;GO:0007411//axon guidance","K06491//neural cell adhesion molecule","NP_001070150.1//neural cell adhesion molecule 1 isoform 3 precursor [Homo sapiens];NP_001229536.1//neural cell adhesion molecule 1 isoform 5 precursor [Homo sapiens];NP_851996.2//neural cell adhesion molecule 1 isoform 2 precursor [Homo sapiens];BAD92680.1//Neural cell adhesion molecule 1, 120 kDa isoform precursor variant, partial [Homo sapiens];NP_000606.3//neural cell adhesion molecule 1 isoform 1 precursor [Homo sapiens]","6;4;1//3;3//A2MP1"]
[401387,2661,0.01,0.03,1.58496250072116,0.644789870419801,"*",0.499032,"LRRD1","GO:0016323//basolateral plasma membrane;GO:0005737//cytoplasm","NA","GO:0007165//signal transduction;GO:0045199//maintenance of epithelial cell apical/basal polarity","K05917//sterol 14-demethylase [EC:1.14.13.70];K19613//leucine-rich repeat protein SHOC2","NP_001155000.1//leucine-rich repeat and death domain-containing protein 1 [Homo sapiens]","1//3"]
[947,2621,0.01,0.03,1.58496250072116,0.644633443959243,"*",0.499032,"CD34","GO:0009897//external side of plasma membrane;GO:0016324//apical plasma membrane;GO:0005764//lysosome;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0009925//basal plasma membrane;GO:0045171//intercellular bridge;GO:0005887//integral component of plasma membrane;GO:0036053//glomerular endothelium fenestra;GO:0005886//plasma membrane","GO:0030246//carbohydrate binding;GO:0043199//sulfate binding;GO:0008134//transcription factor binding","GO:0008217//regulation of blood pressure;GO:0061042//vascular wound healing;GO:0071971//extracellular exosome assembly;GO:1900041//negative regulation of interleukin-2 secretion;GO:0038001//paracrine signaling;GO:0045766//positive regulation of angiogenesis;GO:0072011//glomerular endothelium development;GO:0072089//stem cell proliferation;GO:0035759//mesangial cell-matrix adhesion;GO:0001935//endothelial cell proliferation;GO:1900035//negative regulation of cellular response to heat;GO:0007165//signal transduction;GO:0042482//positive regulation of odontogenesis;GO:0045019//negative regulation of nitric oxide biosynthetic process;GO:0010628//positive regulation of gene expression;GO:0060290//transdifferentiation;GO:0007160//cell-matrix adhesion;GO:0072254//metanephric glomerular mesangial cell differentiation;GO:1901215//negative regulation of neuron death;GO:0032733//positive regulation of interleukin-10 production;GO:0003094//glomerular filtration;GO:0010629//negative regulation of gene expression;GO:0032720//negative regulation of tumor necrosis factor production;GO:1900168//positive regulation of glial cell-derived neurotrophic factor secretion;GO:0098609//cell-cell adhesion;GO:0071425//hematopoietic stem cell proliferation;GO:0008283//cell proliferation;GO:0048870//cell motility;GO:0071657//positive regulation of granulocyte colony-stimulating factor production;GO:0003158//endothelium development;GO:0030097//hemopoiesis;GO:0050776//regulation of immune response;GO:1900038//negative regulation of cellular response to hypoxia;GO:0030195//negative regulation of blood coagulation;GO:0050900//leukocyte migration;GO:2001214//positive regulation of vasculogenesis;GO:0001894//tissue homeostasis;GO:0071636//positive regulation of transforming growth factor beta production","K06474//CD34 antigen","NP_001020280.1//hematopoietic progenitor cell antigen CD34 isoform a precursor [Homo sapiens];NP_001764.1//hematopoietic progenitor cell antigen CD34 isoform b precursor [Homo sapiens]","1//3;2//1"]
[6326,8607,0.01,0.03,1.58496250072116,0.529853710178365,"*",0.37379,"SCN2A","GO:0030315//T-tubule;GO:0030424//axon;GO:0031226//intrinsic component of plasma membrane;GO:0034706//sodium channel complex;GO:0005622//intracellular;GO:0033270//paranode region of axon;GO:0005887//integral component of plasma membrane;GO:0001518//voltage-gated sodium channel complex;GO:0014704//intercalated disc;GO:0033268//node of Ranvier;GO:0005886//plasma membrane","GO:0005248//voltage-gated sodium channel activity","GO:0007399//nervous system development;GO:0042552//myelination;GO:0035725//sodium ion transmembrane transport;GO:0051402//neuron apoptotic process;GO:0008627//intrinsic apoptotic signaling pathway in response to osmotic stress;GO:0086010//membrane depolarization during action potential;GO:0019228//neuronal action potential;GO:0006814//sodium ion transport","K04834//voltage-gated sodium channel type II alpha","NP_001035233.1//sodium channel protein type 2 subunit alpha isoform 2 [Homo sapiens];NP_066287.2//sodium channel protein type 2 subunit alpha isoform 1 [Homo sapiens]","1//3;2//1"]
[9247,2379,0.01,0.03,1.58496250072116,0.644477093378608,"*",0.499032,"GCM2","GO:0005634//nucleus","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0043565//sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0060706//cell differentiation involved in embryonic placenta development;GO:0060017//parathyroid gland development;GO:0007275//multicellular organism development;GO:0042063//gliogenesis;GO:0030643//cellular phosphate ion homeostasis;GO:0006874//cellular calcium ion homeostasis;GO:0006366//transcription from RNA polymerase II promoter","K21598//chorion-specific transcription factor GCM","NP_004743.1//chorion-specific transcription factor GCMb [Homo sapiens]","3//A2MP1"]
[140766,5557,0.01,0.03,1.58496250072116,0.39246036625271,"*",0.249274,"ADAMTS14","NA","NA","NA","K08628//a disintegrin and metalloproteinase with thrombospondin motifs 14 [EC:3.4.24.-]","AAL40229.1//a disintegrin-like and metalloprotease with thrombospondin type 1 motif 14 precursor [Homo sapiens]","4;3//A2MP1"]
[442862,1238,0.01,0.03,1.58496250072116,0.999469979833406,"*",0.999032,"PRY2","NA","NA","NA","K07899//Ras-related protein Rab-9A","NP_004667.2//PTPN13-like protein, Y-linked [Homo sapiens]","1//3"]
[79843,2693,0.01,0.03,1.58496250072116,0.643644502866371,"*",0.499032,"FAM124B","GO:0005654//nucleoplasm;GO:0005739//mitochondrion","NA","NA","K09291//nucleoprotein TPR;K09491//stress 70 protein chaperone microsome-associated 60kDa protein","XP_011807312.1//PREDICTED: protein FAM124B isoform X2 [Colobus angolensis palliatus];NP_001116251.1//protein FAM124B isoform a [Homo sapiens]","1//3;2//1"]
[126410,2620,0.01,0.03,1.58496250072116,0.643177115378409,"*",0.499032,"CYP4F22","GO:0031090//organelle membrane;GO:0005789//endoplasmic reticulum membrane","GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0020037//heme binding;GO:0005506//iron ion binding;GO:0004497//monooxygenase activity","GO:0006690//icosanoid metabolic process","K17731//cytochrome P450 family 4 subfamily F polypeptide 22","NP_775754.2//cytochrome P450 4F22 [Homo sapiens]","3//A2MP1"]
[155,2660,0.01,0.03,1.58496250072116,0.643125225332795,"*",0.499032,"ADRB3","GO:0005634//nucleus;GO:0005887//integral component of plasma membrane;GO:0005622//intracellular;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0043235//receptor complex","GO:0051380//norepinephrine binding;GO:0031699//beta-3 adrenergic receptor binding;GO:0015052//beta3-adrenergic receptor activity;GO:0051379//epinephrine binding;GO:0004939//beta-adrenergic receptor activity;GO:0042803//protein homodimerization activity","GO:0001659//temperature homeostasis;GO:0031649//heat generation;GO:0046677//response to antibiotic;GO:0006112//energy reserve metabolic process;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0005975//carbohydrate metabolic process;GO:0040015//negative regulation of multicellular organism growth;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0002024//diet induced thermogenesis;GO:0009409//response to cold;GO:0042755//eating behavior;GO:0007267//cell-cell signaling;GO:0006091//generation of precursor metabolites and energy;GO:0007568//aging;GO:0071880//adenylate cyclase-activating adrenergic receptor signaling pathway;GO:0007190//activation of adenylate cyclase activity;GO:0050873//brown fat cell differentiation;GO:0043410//positive regulation of MAPK cascade;GO:0002025//norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger","K04143//adrenergic receptor beta-3","NP_000016.1//beta-3 adrenergic receptor [Homo sapiens]","2//1"]
[149647,2332,0.01,0.03,1.58496250072116,0.642917748850714,"*",0.499032,"FAM71A","GO:0005634//nucleus","NA","NA","K10772//AP endonuclease 2 [EC:4.2.99.18];K06568//mucin-1;K12374//arylsulfatase D/F/H [EC:3.1.6.-]","NP_705834.2//protein FAM71A [Homo sapiens]","3//A2MP1"]
[11255,2680,0.01,0.03,1.58496250072116,0.642814060801548,"*",0.499032,"HRH3","GO:0005887//integral component of plasma membrane;GO:0098793//presynapse;GO:0005886//plasma membrane","GO:0004969//histamine receptor activity","GO:0014050//negative regulation of glutamate secretion;GO:0050890//cognition;GO:0007269//neurotransmitter secretion;GO:0007194//negative regulation of adenylate cyclase activity;GO:0014061//regulation of norepinephrine secretion;GO:0014063//negative regulation of serotonin secretion;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger","K04151//histamine receptor H3","NP_009163.2//histamine H3 receptor [Homo sapiens]","2//1"]
[696,2859,0.01,0.03,1.58496250072116,0.64271040619205,"*",0.499032,"BTN1A1","GO:0005615//extracellular space;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004872//receptor activity","NA","K06712//butyrophilin","XP_005249397.2//PREDICTED: butyrophilin subfamily 1 member A1 isoform X1 [Homo sapiens]","2//1"]
[4283,2723,0.01,0.03,1.58496250072116,0.642554986941802,"*",0.499032,"CXCL9","GO:0005615//extracellular space;GO:0009897//external side of plasma membrane;GO:0005623//cell;GO:0005576//extracellular region","GO:0005125//cytokine activity;GO:0048248//CXCR3 chemokine receptor binding;GO:0008009//chemokine activity","GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0042127//regulation of cell proliferation;GO:0032496//response to lipopolysaccharide;GO:0030816//positive regulation of cAMP metabolic process;GO:0010818//T cell chemotaxis;GO:0006935//chemotaxis;GO:1901741//positive regulation of myoblast fusion;GO:0043950//positive regulation of cAMP-mediated signaling;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0070098//chemokine-mediated signaling pathway;GO:0051607//defense response to virus;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0031640//killing of cells of other organism;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0006968//cellular defense response;GO:0006954//inflammatory response;GO:0006952//defense response;GO:0006955//immune response;GO:0045663//positive regulation of myoblast differentiation","K05416//C-X-C motif chemokine 9","XP_007997133.1//PREDICTED: C-X-C motif chemokine 9 [Chlorocebus sabaeus]","2//1"]
[64063,1391,0.06,0.18,1.58496250072116,0.529571748115299,"*",0.37379,"PRSS22","GO:0005576//extracellular region;GO:0046658//anchored component of plasma membrane;GO:0019897//extrinsic component of plasma membrane","GO:0004252//serine-type endopeptidase activity;GO:0008236//serine-type peptidase activity","NA","K09626//brain-specific serine protease 4 [EC:3.4.21.-]","AAQ88762.1//PRSS22, partial [Homo sapiens]","3//A2MP1"]
[56097,4641,0.01,0.03,1.58496250072116,0.642296121827411,"*",0.499032,"PCDHGC5","GO:0070062//extracellular exosome;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005509//calcium ion binding","GO:0007399//nervous system development;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007267//cell-cell signaling;GO:0050808//synapse organization","K16497//protocadherin gamma subfamily C","NP_115783.1//protocadherin gamma-C5 isoform 2 precursor [Homo sapiens];NP_061752.1//protocadherin gamma-C5 isoform 1 precursor [Homo sapiens]","1//3;2//1"]
[64240,2740,0.01,0.03,1.58496250072116,0.642037465206186,"*",0.499032,"ABCG5","GO:0016324//apical plasma membrane;GO:0043190//ATP-binding cassette (ABC) transporter complex;GO:0005886//plasma membrane;GO:0043235//receptor complex","GO:0005524//ATP binding;GO:0046982//protein heterodimerization activity;GO:0042626//ATPase activity, coupled to transmembrane movement of substances;GO:0017127//cholesterol transporter activity;GO:0016887//ATPase activity","GO:0055085//transmembrane transport;GO:0010212//response to ionizing radiation;GO:0007588//excretion;GO:0033344//cholesterol efflux;GO:0045796//negative regulation of intestinal cholesterol absorption;GO:0030299//intestinal cholesterol absorption;GO:0007584//response to nutrient;GO:0042632//cholesterol homeostasis;GO:0010949//negative regulation of intestinal phytosterol absorption;GO:0006855//drug transmembrane transport","K05683//ATP-binding cassette, subfamily G (WHITE), member 5 (sterolin 1)","NP_071881.1//ATP-binding cassette sub-family G member 5 [Homo sapiens]","2//1"]
[339862,2344,0.01,0.03,1.58496250072116,0.641985758878956,"*",0.499032,"LOC339862","NA","NA","NA","NA","NP_001244106.1//uncharacterized protein LOC339862 [Homo sapiens]","1//3"]
[219681,2529,0.01,0.03,1.58496250072116,0.641882371205411,"*",0.499032,"ARMC3","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005737//cytoplasm","NA","NA","K12642//plakophilin 2;K08332//vacuolar protein 8","EAW86138.1//armadillo repeat containing 3, isoform CRA_b [Homo sapiens];NP_775104.2//armadillo repeat-containing protein 3 isoform 1 [Homo sapiens];NP_001269675.1//armadillo repeat-containing protein 3 isoform 3 [Homo sapiens];NP_001269674.1//armadillo repeat-containing protein 3 isoform 2 [Homo sapiens]","4;1//3"]
[1441,3419,0.01,0.03,1.58496250072116,0.64162404764971,"*",0.499032,"CSF3R","GO:0005887//integral component of plasma membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0004872//receptor activity;GO:0051916//granulocyte colony-stimulating factor binding;GO:0004896//cytokine receptor activity","GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0030593//neutrophil chemotaxis;GO:0006952//defense response;GO:0045637//regulation of myeloid cell differentiation;GO:0097186//amelogenesis","K05061//granulocyte colony-stimulating factor receptor","NP_000751.1//granulocyte colony-stimulating factor receptor isoform a precursor [Homo sapiens];NP_724781.1//granulocyte colony-stimulating factor receptor isoform c precursor [Homo sapiens];NP_758519.1//granulocyte colony-stimulating factor receptor isoform d precursor [Homo sapiens]","3//A2MP1;2//1"]
[401447,1593,0.01,0.03,1.58496250072116,0.999344803556891,"*",0.999032,"USP17L1","GO:0005783//endoplasmic reticulum;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005789//endoplasmic reticulum membrane","GO:0004843//thiol-dependent ubiquitin-specific protease activity;GO:0036459//thiol-dependent ubiquitinyl hydrolase activity","GO:0071108//protein K48-linked deubiquitination;GO:0042127//regulation of cell proliferation;GO:0043547//positive regulation of GTPase activity;GO:0071586//CAAX-box protein processing;GO:0010955//negative regulation of protein processing;GO:1900245//positive regulation of MDA-5 signaling pathway;GO:0006511//ubiquitin-dependent protein catabolic process;GO:1900027//regulation of ruffle assembly;GO:0030334//regulation of cell migration;GO:0016579//protein deubiquitination;GO:0031064//negative regulation of histone deacetylation;GO:0070536//protein K63-linked deubiquitination;GO:0090315//negative regulation of protein targeting to membrane;GO:0006915//apoptotic process;GO:0007093//mitotic cell cycle checkpoint;GO:1900246//positive regulation of RIG-I signaling pathway;GO:0034260//negative regulation of GTPase activity;GO:0050691//regulation of defense response to virus by host;GO:0042981//regulation of apoptotic process","K11845//ubiquitin carboxyl-terminal hydrolase 17 [EC:3.4.19.12]","NP_001243800.1//ubiquitin carboxyl-terminal hydrolase 17-like protein 3 [Homo sapiens]","1//3"]
[645836,1593,0.01,0.03,1.58496250072116,0.999219658631269,"*",0.999032,"USP17L3","GO:0005634//nucleus;GO:0005783//endoplasmic reticulum","GO:0036459//thiol-dependent ubiquitinyl hydrolase activity","GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination;GO:0006915//apoptotic process","K11845//ubiquitin carboxyl-terminal hydrolase 17 [EC:3.4.19.12]","NP_001243800.1//ubiquitin carboxyl-terminal hydrolase 17-like protein 3 [Homo sapiens]","1//3"]
[10840,3204,0.01,0.03,1.58496250072116,0.641108023805694,"*",0.499032,"ALDH1L1","NA","GO:0016742//hydroxymethyl-, formyl- and related transferase activity;GO:0016491//oxidoreductase activity","GO:0009058//biosynthetic process","K00289//formyltetrahydrofolate dehydrogenase [EC:1.5.1.6]","XP_011924019.1//PREDICTED: cytosolic 10-formyltetrahydrofolate dehydrogenase isoform X2 [Cercocebus atys];XP_011826910.1//PREDICTED: cytosolic 10-formyltetrahydrofolate dehydrogenase isoform X2 [Mandrillus leucophaeus];XP_010378871.1//PREDICTED: cytosolic 10-formyltetrahydrofolate dehydrogenase isoform X3 [Rhinopithecus roxellana]","1//3;3//A2MP1"]
[338809,2369,0.01,0.03,1.58496250072116,0.641056467068758,"*",0.499032,"C12orf74","NA","NA","NA","NA","EAW97470.1//hypothetical protein LOC338809, partial [Homo sapiens]","3//A2MP1;2//1"]
[6247,3040,0.01,0.03,1.58496250072116,0.640747300699301,"*",0.499032,"RS1","GO:0005615//extracellular space;GO:0019897//extrinsic component of plasma membrane","GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0010314//phosphatidylinositol-5-phosphate binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0070492//oligosaccharide binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0080025//phosphatidylinositol-3,5-bisphosphate binding;GO:0070273//phosphatidylinositol-4-phosphate binding;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding;GO:0001786//phosphatidylserine binding","GO:0016062//adaptation of rhodopsin mediated signaling;GO:0007155//cell adhesion;GO:0007275//multicellular organism development;GO:0007601//visual perception;GO:0051260//protein homooligomerization;GO:0010842//retina layer formation","K16669//protocadherin Fat 4;K03902//coagulation factor V (labile factor)","NP_000321.1//retinoschisin precursor [Homo sapiens]","3//A2MP1"]
[4322,2735,0.03,0.09,1.58496250072116,0.529337008865248,"*",0.37379,"MMP13","GO:0031012//extracellular matrix;GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix","GO:0004252//serine-type endopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0005518//collagen binding;GO:0005509//calcium ion binding;GO:0008270//zinc ion binding","GO:0022617//extracellular matrix disassembly;GO:0001958//endochondral ossification;GO:0044267//cellular protein metabolic process;GO:0030282//bone mineralization;GO:0006508//proteolysis;GO:0003417//growth plate cartilage development;GO:0060349//bone morphogenesis;GO:0030574//collagen catabolic process","K07994//matrix metalloproteinase-13 (collagenase 3) [EC:3.4.24.-]","NP_002418.1//collagenase 3 preproprotein [Homo sapiens]","3//A2MP1"]
[56111,4778,0.01,0.03,1.58496250072116,0.640386983290488,"*",0.499032,"PCDHGA4","NA","NA","NA","K16495//protocadherin gamma subfamily A","XP_010592269.1//PREDICTED: LOW QUALITY PROTEIN: protocadherin gamma-A4-like [Loxodonta africana]","3//A2MP1;2//1"]
[945,1108,0.04,0.12,1.58496250072116,0.640181269514937,"*",0.499032,"CD33","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0009897//external side of plasma membrane;GO:0005887//integral component of plasma membrane;GO:0035579//specific granule membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0070821//tertiary granule membrane","GO:0030246//carbohydrate binding;GO:0004872//receptor activity","GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0043312//neutrophil degranulation;GO:0007267//cell-cell signaling;GO:0050776//regulation of immune response;GO:0008285//negative regulation of cell proliferation","K06473//CD33 antigen","XP_011525833.1//PREDICTED: myeloid cell surface antigen CD33 isoform X1 [Homo sapiens];XP_016882999.1//PREDICTED: myeloid cell surface antigen CD33 isoform X4 [Homo sapiens]","1//3;3//A2MP1"]
[816,4097,0.02,0.06,1.58496250072116,0.529290085985285,"*",0.37379,"CAMK2B","GO:0005654//nucleoplasm;GO:0005815//microtubule organizing center;GO:0030666//endocytic vesicle membrane;GO:0005737//cytoplasm;GO:0043005//neuron projection;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0033017//sarcoplasmic reticulum membrane","GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0003779//actin binding;GO:0004674//protein serine/threonine kinase activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0004672//protein kinase activity;GO:0004683//calmodulin-dependent protein kinase activity;GO:0005516//calmodulin binding","GO:0014733//regulation of skeletal muscle adaptation;GO:0060998//regulation of dendritic spine development;GO:0035556//intracellular signal transduction;GO:0051823//regulation of synapse structural plasticity;GO:0051924//regulation of calcium ion transport;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0000165//MAPK cascade;GO:0007165//signal transduction;GO:0006468//protein phosphorylation;GO:0010976//positive regulation of neuron projection development;GO:0046777//protein autophosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:1900034//regulation of cellular response to heat;GO:0018105//peptidyl-serine phosphorylation;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0061003//positive regulation of dendritic spine morphogenesis;GO:0090129//positive regulation of synapse maturation","K04515//calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]","NP_742080.1//calcium/calmodulin-dependent protein kinase type II subunit beta isoform 7 [Homo sapiens];NP_001211.3//calcium/calmodulin-dependent protein kinase type II subunit beta isoform 1 [Homo sapiens];NP_742076.1//calcium/calmodulin-dependent protein kinase type II subunit beta isoform 3 [Homo sapiens];NP_742078.1//calcium/calmodulin-dependent protein kinase type II subunit beta isoform 5 [Homo sapiens];NP_742081.1//calcium/calmodulin-dependent protein kinase type II subunit beta isoform 8 [Homo sapiens];NP_742077.1//calcium/calmodulin-dependent protein kinase type II subunit beta isoform 4 [Homo sapiens];NP_742075.1//calcium/calmodulin-dependent protein kinase type II subunit beta isoform 2 [Homo sapiens];NP_742079.1//calcium/calmodulin-dependent protein kinase type II subunit beta isoform 6 [Homo sapiens]","1//3;4;2//1"]
[140706,2532,0.01,0.03,1.58496250072116,0.639411018528916,"*",0.499032,"CCM2L","NA","NA","GO:0003222//ventricular trabecula myocardium morphogenesis;GO:0034111//negative regulation of homotypic cell-cell adhesion;GO:0003209//cardiac atrium morphogenesis;GO:0090271//positive regulation of fibroblast growth factor production;GO:0032091//negative regulation of protein binding;GO:0042060//wound healing;GO:0055017//cardiac muscle tissue growth","K19475//WAS/WASL-interacting protein;K05747//Wiskott-Aldrich syndrome protein;K05748//WAS protein family, member 2","NP_542192.2//cerebral cavernous malformations 2 protein-like [Homo sapiens]","3//A2MP1"]
[25891,2818,0.01,0.03,1.58496250072116,0.639257190697674,"*",0.499032,"PAMR1","GO:0005615//extracellular space","GO:0004252//serine-type endopeptidase activity;GO:0005509//calcium ion binding","NA","K17495//CUB and sushi domain-containing protein;K05502//bone morphogenetic protein 1 [EC:3.4.24.19]","NP_001001991.1//inactive serine protease PAMR1 isoform b precursor [Homo sapiens];EAW68140.1//regeneration associated muscle protease [Homo sapiens];NP_001269605.1//inactive serine protease PAMR1 isoform d precursor [Homo sapiens]","1//3;3//A2MP1;2//1"]
[170680,1185,0.07,0.21,1.58496250072116,0.531173513032648,"*",0.37379,"PSORS1C2","GO:0005576//extracellular region","NA","NA","K16760//coiled-coil alpha-helical rod protein 1;K10572//inositol-pentakisphosphate 2-kinase [EC:2.7.1.158];K07604//type I keratin, acidic","XP_005553644.1//PREDICTED: psoriasis susceptibility 1 candidate gene 2 protein [Macaca fascicularis]","2//1"]
[387715,833,0.1,0.3,1.58496250072116,0.530795756067206,"*",0.37379,"ARMS2","GO:0001917//photoreceptor inner segment;GO:0005739//mitochondrion","NA","GO:0001895//retina homeostasis","NA","NP_001093137.1//age-related maculopathy susceptibility protein 2 [Homo sapiens]","2//1"]
[3861,1653,0.05,0.15,1.58496250072116,0.530748574222222,"*",0.37379,"KRT14","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005829//cytosol;GO:0071944//cell periphery;GO:0045095//keratin filament;GO:0005882//intermediate filament;GO:0005737//cytoplasm;GO:0045178//basal part of cell","GO:1990254//keratin filament binding;GO:0005200//structural constituent of cytoskeleton","GO:0045110//intermediate filament bundle assembly;GO:0010212//response to ionizing radiation;GO:0010043//response to zinc ion;GO:0031424//keratinization;GO:0031581//hemidesmosome assembly;GO:0070268//cornification;GO:0007568//aging;GO:0008544//epidermis development;GO:0042633//hair cycle","K07604//type I keratin, acidic","XP_003279474.2//PREDICTED: keratin, type I cytoskeletal 14 [Nomascus leucogenys]",4]
[284451,1607,0.05,0.15,1.58496250072116,0.530701400764377,"*",0.37379,"ODF3L2","GO:0005881//cytoplasmic microtubule","NA","NA","K19719//collagen, type II, alpha;K19475//WAS/WASL-interacting protein;K21125//mucin-5AC","NP_872383.1//outer dense fiber protein 3-like protein 2 [Homo sapiens]","2//1"]
[3483,2168,0.07,0.21,1.58496250072116,0.303802091806767,"*",0.1787362,"IGFALS","GO:0070062//extracellular exosome;GO:0005654//nucleoplasm;GO:0042567//insulin-like growth factor ternary complex;GO:0005615//extracellular space;GO:0005576//extracellular region","GO:0005520//insulin-like growth factor binding","GO:0044267//cellular protein metabolic process;GO:0007155//cell adhesion;GO:0007165//signal transduction","K17256//insulin-like growth factor-binding protein complex acid labile subunit","NP_004961.1//insulin-like growth factor-binding protein complex acid labile subunit isoform 2 precursor [Homo sapiens];NP_001139478.1//insulin-like growth factor-binding protein complex acid labile subunit isoform 1 precursor [Homo sapiens]","1//3;2//1"]
[57393,1580,0.05,0.15,1.58496250072116,0.529477827436375,"*",0.37379,"CLTRN","GO:0070062//extracellular exosome;GO:0031526//brush border membrane;GO:0016021//integral component of membrane;GO:0005737//cytoplasm","GO:0008241//peptidyl-dipeptidase activity;GO:0008237//metallopeptidase activity","GO:0051957//positive regulation of amino acid transport;GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0045956//positive regulation of calcium ion-dependent exocytosis;GO:0035543//positive regulation of SNARE complex assembly","K20004//collectrin","XP_016798474.1//PREDICTED: collectrin [Pan troglodytes]",5]
[3592,1329,1.28,3.82,1.57742882803575,{"v":7.12957361350099e-06,"d":"7.13E-06"},"Up",{"v":1.34879E-6,"d":"1.35E-06"},"IL12A","GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0043514//interleukin-12 complex;GO:0005576//extracellular region;GO:0031906//late endosome lumen;GO:0005737//cytoplasm","GO:0008083//growth factor activity;GO:0005125//cytokine activity;GO:0042163//interleukin-12 beta subunit binding;GO:0046982//protein heterodimerization activity;GO:0045513//interleukin-27 binding;GO:0005143//interleukin-12 receptor binding","GO:0016477//cell migration;GO:0097191//extrinsic apoptotic signaling pathway;GO:0042102//positive regulation of T cell proliferation;GO:0051135//positive regulation of NK T cell activation;GO:0045785//positive regulation of cell adhesion;GO:0071222//cellular response to lipopolysaccharide;GO:0032496//response to lipopolysaccharide;GO:0007050//cell cycle arrest;GO:0035744//T-helper 1 cell cytokine production;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0032816//positive regulation of natural killer cell activation;GO:0008283//cell proliferation;GO:0045582//positive regulation of T cell differentiation;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0050830//defense response to Gram-positive bacterium;GO:0032729//positive regulation of interferon-gamma production;GO:0035722//interleukin-12-mediated signaling pathway;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0002860//positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target;GO:0042832//defense response to protozoan;GO:2000510//positive regulation of dendritic cell chemotaxis;GO:0050671//positive regulation of lymphocyte proliferation;GO:0032946//positive regulation of mononuclear cell proliferation;GO:0010224//response to UV-B;GO:0034393//positive regulation of smooth muscle cell apoptotic process;GO:0032609//interferon-gamma production;GO:0032700//negative regulation of interleukin-17 production;GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0006955//immune response;GO:0098586//cellular response to virus;GO:0009615//response to virus","K05406//interleukin 12A","NP_001341512.1//interleukin-12 subunit alpha isoform 3 [Homo sapiens];XP_008981813.2//PREDICTED: interleukin-12 subunit alpha [Callithrix jacchus]","1//3;3//A2MP1"]
[23586,4759,1.3,3.86,1.57008922423963,{"v":5.07808630235162e-18,"d":"5.08E-18"},"Up",{"v":2.83882e-19,"d":"2.84E-19"},"DDX58","GO:0005829//cytosol;GO:0005923//bicellular tight junction;GO:0015629//actin cytoskeleton;GO:0032587//ruffle membrane;GO:0005737//cytoplasm","GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0004386//helicase activity;GO:0003725//double-stranded RNA binding;GO:0003690//double-stranded DNA binding;GO:0008270//zinc ion binding;GO:0003727//single-stranded RNA binding","GO:0032755//positive regulation of interleukin-6 production;GO:0060760//positive regulation of response to cytokine stimulus;GO:0030334//regulation of cell migration;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0035549//positive regulation of interferon-beta secretion;GO:0016579//protein deubiquitination;GO:0045087//innate immune response;GO:2000778//positive regulation of interleukin-6 secretion;GO:0039528//cytoplasmic pattern recognition receptor signaling pathway in response to virus;GO:0032728//positive regulation of interferon-beta production;GO:0009597//detection of virus;GO:0071360//cellular response to exogenous dsRNA;GO:0051607//defense response to virus;GO:0032727//positive regulation of interferon-alpha production;GO:0032757//positive regulation of interleukin-8 production;GO:0016032//viral process;GO:0034344//regulation of type III interferon production;GO:0010628//positive regulation of gene expression;GO:1904469//positive regulation of tumor necrosis factor secretion;GO:0032725//positive regulation of granulocyte macrophage colony-stimulating factor production;GO:0039529//RIG-I signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:1902741//positive regulation of interferon-alpha secretion;GO:0032480//negative regulation of type I interferon production;GO:0009615//response to virus;GO:0002230//positive regulation of defense response to virus by host;GO:0042993//positive regulation of transcription factor import into nucleus","K12646//ATP-dependent RNA helicase DDX58 [EC:3.6.3.14]","NP_055129.2//probable ATP-dependent RNA helicase DDX58 [Homo sapiens]","3//A2MP1"]
[121504,412,0.22,0.65,1.56293619439116,0.530324314770406,"*",0.37379,"HIST4H4","NA","NA","NA","K11254//histone H4","XP_009423180.2//PREDICTED: histone H4 [Pan troglodytes]","2//1"]
[2258,2450,0.2,0.59,1.56071495447448,0.0356574052867522,"*",0.0144402,"FGF13","GO:0030425//dendrite;GO:0030424//axon;GO:0005634//nucleus;GO:0005874//microtubule;GO:0005737//cytoplasm;GO:0043005//neuron projection;GO:0030175//filopodium;GO:0030426//growth cone;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005576//extracellular region;GO:0014704//intercalated disc;GO:0016328//lateral plasma membrane;GO:0005886//plasma membrane","GO:0044325//ion channel binding;GO:0008083//growth factor activity;GO:0048487//beta-tubulin binding;GO:0017080//sodium channel regulator activity;GO:0030295//protein kinase activator activity;GO:0008017//microtubule binding","GO:0007399//nervous system development;GO:0021766//hippocampus development;GO:1990834//response to odorant;GO:0021795//cerebral cortex cell migration;GO:0007026//negative regulation of microtubule depolymerization;GO:0006814//sodium ion transport;GO:0048671//negative regulation of collateral sprouting;GO:0000165//MAPK cascade;GO:0072659//protein localization to plasma membrane;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0098909//regulation of cardiac muscle cell action potential involved in regulation of contraction;GO:0045200//establishment of neuroblast polarity;GO:0007612//learning;GO:0007613//memory;GO:0001764//neuron migration;GO:0046785//microtubule polymerization","K04358//fibroblast growth factor","NP_001132970.1//fibroblast growth factor 13 isoform 4 [Homo sapiens];NP_001132972.1//fibroblast growth factor 13 isoform 2 [Homo sapiens];NP_378668.1//fibroblast growth factor 13 isoform 5 [Homo sapiens];NP_004105.1//fibroblast growth factor 13 isoform 1 [Homo sapiens];XP_011811213.1//PREDICTED: fibroblast growth factor 13 isoform X2 [Colobus angolensis palliatus]","1//3;3//A2MP1;2//1"]
[54659,2345,0.17,0.5,1.55639334852439,0.0454280472934132,"*",0.01899708,"UGT1A3","GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0046982//protein heterodimerization activity;GO:0015020//glucuronosyltransferase activity;GO:0001972//retinoic acid binding;GO:0042803//protein homodimerization activity;GO:0019899//enzyme binding","GO:2001030//negative regulation of cellular glucuronidation;GO:0008152//metabolic process;GO:0052697//xenobiotic glucuronidation;GO:0042573//retinoic acid metabolic process;GO:0052695//cellular glucuronidation;GO:0045922//negative regulation of fatty acid metabolic process;GO:1904224//negative regulation of glucuronosyltransferase activity;GO:0052696//flavonoid glucuronidation","K00699//glucuronosyltransferase [EC:2.4.1.17]","NP_061966.1//UDP-glucuronosyltransferase 1-3 precursor [Homo sapiens]","2//1"]
[3039,627,0.14,0.41,1.55019708256048,0.529994803834546,"*",0.37379,"HBA1","GO:0005833//hemoglobin complex","GO:0020037//heme binding;GO:0005506//iron ion binding;GO:0005344//oxygen carrier activity;GO:0019825//oxygen binding","NA","K13822//hemoglobin subunit alpha","SAI82135.1//TPA: globin C1 [Homo sapiens]",4]
[154,2058,0.31,0.9,1.5376567859428,0.0185310238571669,"*",0.00688736,"ADRB2","GO:0016020//membrane;GO:0010008//endosome membrane;GO:0005634//nucleus;GO:0016324//apical plasma membrane;GO:0005764//lysosome;GO:0043235//receptor complex;GO:0005768//endosome;GO:0005887//integral component of plasma membrane;GO:0030665//clathrin-coated vesicle membrane;GO:0005886//plasma membrane;GO:0005769//early endosome","GO:0001540//amyloid-beta binding;GO:0015459//potassium channel regulator activity;GO:0051379//epinephrine binding;GO:0042803//protein homodimerization activity;GO:0008179//adenylate cyclase binding;GO:0051380//norepinephrine binding;GO:0004941//beta2-adrenergic receptor activity;GO:0032403//protein complex binding","GO:0031649//heat generation;GO:0007171//activation of transmembrane receptor protein tyrosine kinase activity;GO:0002028//regulation of sodium ion transport;GO:0007166//cell surface receptor signaling pathway;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0016579//protein deubiquitination;GO:0071875//adrenergic receptor signaling pathway;GO:0040015//negative regulation of multicellular organism growth;GO:0002024//diet induced thermogenesis;GO:0010739//positive regulation of protein kinase A signaling;GO:1990911//response to psychosocial stress;GO:2000969//positive regulation of AMPA receptor activity;GO:0071880//adenylate cyclase-activating adrenergic receptor signaling pathway;GO:1901098//positive regulation of autophagosome maturation;GO:0006898//receptor-mediated endocytosis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0050873//brown fat cell differentiation;GO:2000481//positive regulation of cAMP-dependent protein kinase activity;GO:0002025//norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure;GO:0045986//negative regulation of smooth muscle contraction;GO:0061885//positive regulation of mini excitatory postsynaptic potential;GO:0002032//desensitization of G-protein coupled receptor protein signaling pathway by arrestin;GO:0008333//endosome to lysosome transport;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0045453//bone resorption;GO:1904504//positive regulation of lipophagy;GO:0009409//response to cold;GO:0007267//cell-cell signaling;GO:0031398//positive regulation of protein ubiquitination;GO:1904646//cellular response to amyloid-beta;GO:0061024//membrane organization;GO:0007190//activation of adenylate cyclase activity;GO:0030501//positive regulation of bone mineralization;GO:0043410//positive regulation of MAPK cascade","K04142//adrenergic receptor beta-2","BAD96745.1//Adrenergic, beta-2-, receptor, surface variant, partial [Homo sapiens]",5]
[7074,5594,0.1,0.29,1.53605290024021,0.0662016338373752,"*",0.0290518,"TIAM1","GO:0005634//nucleus;GO:0044295//axonal growth cone;GO:0005874//microtubule;GO:0044304//main axon;GO:0044291//cell-cell contact zone;GO:0032587//ruffle membrane;GO:0014069//postsynaptic density;GO:0043025//neuronal cell body;GO:0005911//cell-cell junction;GO:0005829//cytosol;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0043197//dendritic spine;GO:0005886//plasma membrane","GO:0008289//lipid binding;GO:0005057//signal transducer activity, downstream of receptor;GO:0030971//receptor tyrosine kinase binding;GO:0030676//Rac guanyl-nucleotide exchange factor activity;GO:0019900//kinase binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0008017//microtubule binding;GO:0005089//Rho guanyl-nucleotide exchange factor activity","GO:0016477//cell migration;GO:0030335//positive regulation of cell migration;GO:0010717//regulation of epithelial to mesenchymal transition;GO:1904338//regulation of dopaminergic neuron differentiation;GO:0072657//protein localization to membrane;GO:0032092//positive regulation of protein binding;GO:0098989//NMDA selective glutamate receptor signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:1990138//neuron projection extension;GO:2000050//regulation of non-canonical Wnt signaling pathway;GO:0061178//regulation of insulin secretion involved in cellular response to glucose stimulus;GO:1905274//regulation of modification of postsynaptic actin cytoskeleton;GO:0090630//activation of GTPase activity;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0048013//ephrin receptor signaling pathway;GO:0050772//positive regulation of axonogenesis;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:1904268//positive regulation of Schwann cell chemotaxis;GO:0043507//positive regulation of JUN kinase activity;GO:0006915//apoptotic process;GO:0003300//cardiac muscle hypertrophy;GO:0016601//Rac protein signal transduction;GO:0007160//cell-matrix adhesion;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0035023//regulation of Rho protein signal transduction;GO:0042220//response to cocaine;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0061003//positive regulation of dendritic spine morphogenesis;GO:0008284//positive regulation of cell proliferation","K05731//T-lymphoma invasion and metastasis-inducing protein 1","NP_003244.2//T-lymphoma invasion and metastasis-inducing protein 1 isoform 1 [Homo sapiens];NP_001340616.1//T-lymphoma invasion and metastasis-inducing protein 1 isoform 4 [Homo sapiens];NP_001340614.1//T-lymphoma invasion and metastasis-inducing protein 1 isoform 3 [Homo sapiens];NP_001340615.1//T-lymphoma invasion and metastasis-inducing protein 1 isoform 4 [Homo sapiens];XP_006155328.1//PREDICTED: T-lymphoma invasion and metastasis-inducing protein 1 isoform X2 [Tupaia chinensis]","1//3;3//A2MP1"]
[127670,2500,0.09,0.26,1.53051471669878,0.131590028151154,"*",0.064963,"TEDDM1","NA","NA","NA","K22069//LYR motif-containing protein 4;K12581//CCR4-NOT transcription complex subunit 7/8;K08857//NIMA (never in mitosis gene a)-related kinase 1/4/5 [EC:2.7.11.1];K06588//integrin beta 5;K01064//wingless-type MMTV integration site family, member 9","XP_003775525.1//PREDICTED: transmembrane epididymal protein 1 [Pongo abelii]","3//A2MP1"]
[118663,1877,0.09,0.26,1.53051471669878,0.303899101522086,"*",0.1787362,"BTBD16","GO:0005634//nucleus;GO:0000151//ubiquitin ligase complex","NA","NA","K10487//BTB/POZ domain-containing protein 16","NP_001305118.1//BTB/POZ domain-containing protein 16 isoform a [Homo sapiens];NP_653188.2//BTB/POZ domain-containing protein 16 isoform b [Homo sapiens]","1//3;3//A2MP1"]
[50617,3049,0.08,0.23,1.52356195605701,0.175888715625,"*",0.091611,"ATP6V0A4","GO:0005765//lysosomal membrane;GO:0070062//extracellular exosome;GO:0010008//endosome membrane;GO:0000220//vacuolar proton-transporting V-type ATPase, V0 domain;GO:0005903//brush border;GO:0016324//apical plasma membrane;GO:0031526//brush border membrane;GO:0030670//phagocytic vesicle membrane;GO:0005768//endosome;GO:0016021//integral component of membrane;GO:0045177//apical part of cell;GO:0016471//vacuolar proton-transporting V-type ATPase complex;GO:0005886//plasma membrane","GO:0015078//hydrogen ion transmembrane transporter activity;GO:0051117//ATPase binding;GO:0046961//proton-transporting ATPase activity, rotational mechanism","GO:0008286//insulin receptor signaling pathway;GO:0034220//ion transmembrane transport;GO:0006885//regulation of pH;GO:0007588//excretion;GO:0070072//vacuolar proton-transporting V-type ATPase complex assembly;GO:0090383//phagosome acidification;GO:0007035//vacuolar acidification;GO:0001503//ossification;GO:0015986//ATP synthesis coupled proton transport;GO:0015991//ATP hydrolysis coupled proton transport;GO:0007605//sensory perception of sound;GO:0033572//transferrin transport;GO:0015992//proton transport","K02154//V-type H+-transporting ATPase subunit a","NP_065683.2//V-type proton ATPase 116 kDa subunit a isoform 4 [Homo sapiens]","2//1"]
[9478,1196,0.08,0.23,1.52356195605701,0.355921044901299,"*",0.217844,"CABP1","GO:0005856//cytoskeleton;GO:0005615//extracellular space;GO:0005938//cell cortex;GO:0030054//cell junction;GO:0014069//postsynaptic density;GO:0048471//perinuclear region of cytoplasm;GO:0000139//Golgi membrane;GO:0005886//plasma membrane;GO:0045211//postsynaptic membrane","GO:0005509//calcium ion binding;GO:0004857//enzyme inhibitor activity;GO:0048306//calcium-dependent protein binding;GO:0008139//nuclear localization sequence binding","GO:0042308//negative regulation of protein import into nucleus","K02183//calmodulin","NP_001028849.1//calcium-binding protein 1 isoform 3 [Homo sapiens];XP_014956896.1//PREDICTED: calcium-binding protein 1 isoform X1 [Ovis aries];EDL19873.1//calcium binding protein 1, isoform CRA_a, partial [Mus musculus]","4;1//3;3//A2MP1"]
[8638,2093,0.28,0.8,1.51457317282976,0.0159946116129032,"*",0.00583552,"OASL","GO:0016020//membrane;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0003677//DNA binding;GO:0046966//thyroid hormone receptor binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0003725//double-stranded RNA binding","GO:0060333//interferon-gamma-mediated signaling pathway;GO:0060337//type I interferon signaling pathway;GO:0045071//negative regulation of viral genome replication;GO:0006955//immune response;GO:0051607//defense response to virus;GO:0009615//response to virus","K14608//2'-5'-oligoadenylate synthase-like protein","NP_003724.1//2'-5'-oligoadenylate synthase-like protein isoform a [Homo sapiens];NP_937856.1//2'-5'-oligoadenylate synthase-like protein isoform b [Homo sapiens];NP_001248754.1//2'-5'-oligoadenylate synthase-like protein isoform c [Homo sapiens]","1//3;3//A2MP1;2//1"]
[138715,1239,0.07,0.2,1.51457317282976,0.530512790759662,"*",0.37379,"ARID3C","GO:0005634//nucleus;GO:0045121//membrane raft;GO:0005737//cytoplasm","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003682//chromatin binding","NA","K11653//AT-rich interactive domain-containing protein 1;K20719//sigma non-opioid intracellular receptor","XP_016869772.1//PREDICTED: AT-rich interactive domain-containing protein 3C isoform X1 [Homo sapiens]","1//3"]
[49861,1209,0.07,0.2,1.51457317282976,0.529383940065609,"*",0.37379,"CLDN20","GO:0016021//integral component of membrane;GO:0005923//bicellular tight junction;GO:0005886//plasma membrane","GO:0042802//identical protein binding;GO:0005198//structural molecule activity","GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules","K06087//claudin","NP_001001346.1//claudin-20 precursor [Homo sapiens]","3//A2MP1"]
[6773,4573,6.41,18.27,1.51108037200875,{"v":8.74745848421053e-75,"d":"8.75E-75"},"Up",{"v":7.28316e-77,"d":"7.28E-77"},"STAT2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0003677//DNA binding;GO:0042802//identical protein binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0004871//signal transducer activity;GO:0003700//DNA binding transcription factor activity","GO:0060337//type I interferon signaling pathway;GO:0007259//JAK-STAT cascade;GO:0051607//defense response to virus;GO:0006351//transcription, DNA-templated;GO:0016032//viral process;GO:0001932//regulation of protein phosphorylation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0060338//regulation of type I interferon-mediated signaling pathway;GO:0090140//regulation of mitochondrial fission","K11221//signal transducer and activator of transcription 2","NP_938146.1//signal transducer and activator of transcription 2 isoform 2 [Homo sapiens];NP_005410.1//signal transducer and activator of transcription 2 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[4160,1438,0.06,0.17,1.50250034052918,0.530418536022031,"*",0.37379,"MC4R","GO:0005634//nucleus;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0031625//ubiquitin protein ligase binding;GO:0017046//peptide hormone binding;GO:0042923//neuropeptide binding;GO:0004977//melanocortin receptor activity;GO:0004980//melanocyte-stimulating hormone receptor activity","GO:2000821//regulation of grooming behavior;GO:2000252//negative regulation of feeding behavior;GO:0002024//diet induced thermogenesis;GO:0032868//response to insulin;GO:0030073//insulin secretion;GO:0045780//positive regulation of bone resorption;GO:0006112//energy reserve metabolic process;GO:0007631//feeding behavior;GO:0030819//positive regulation of cAMP biosynthetic process;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway","K04202//melanocortin 4 receptor","NP_005903.2//melanocortin receptor 4 [Homo sapiens]","2//1"]
[30014,418,0.3,0.85,1.50250034052918,0.355702755392007,"*",0.217844,"SPANXA1","GO:0005634//nucleus;GO:0005737//cytoplasm","NA","GO:0007283//spermatogenesis","NA","NP_038481.2//sperm protein associated with the nucleus on the X chromosome A [Homo sapiens]","3//A2MP1"]
[9985,2354,1.39,3.91,1.49208372458384,{"v":6.67934701821862e-09,"d":"6.68E-09"},"Up",{"v":8.26242e-10,"d":"8.26E-10"},"REC8","GO:0000228//nuclear chromosome;GO:0005634//nucleus;GO:0001673//male germ cell nucleus;GO:0030893//meiotic cohesin complex;GO:0000778//condensed nuclear chromosome kinetochore;GO:0000798//nuclear cohesin complex;GO:0000800//lateral element;GO:0034991//nuclear meiotic cohesin complex","GO:0003682//chromatin binding","GO:0007141//male meiosis I;GO:0009566//fertilization;GO:0007286//spermatid development;GO:0001556//oocyte maturation;GO:0007283//spermatogenesis;GO:0007130//synaptonemal complex assembly;GO:0006302//double-strand break repair;GO:0007131//reciprocal meiotic recombination;GO:0051321//meiotic cell cycle;GO:0007062//sister chromatid cohesion;GO:0072520//seminiferous tubule development;GO:0000724//double-strand break repair via homologous recombination","K13054//meiotic recombination protein REC8, animal type","NP_005123.2//meiotic recombination protein REC8 homolog [Homo sapiens]","1//3;2//1"]
[164781,1953,0.16,0.45,1.49185309632967,0.150139830997039,"*",0.0761696,"DAW1","GO:0005929//cilium;GO:0005737//cytoplasm","NA","GO:0007368//determination of left/right symmetry;GO:0007507//heart development","K19760//dynein assembly factor with WDR repeat domains 1","NP_849143.1//dynein assembly factor with WDR repeat domains 1 isoform 1 [Homo sapiens]","1//3;2//1"]
[5971,2297,11.01,30.72,1.48036374715679,{"v":1.04943824554913E-60,"d":"1.05E-60"},"Up",{"v":1.136552E-62,"d":"1.14E-62"},"RELB","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005815//microtubule organizing center;GO:0043234//protein complex;GO:0005829//cytosol;GO:0033256//I-kappaB/NF-kappaB complex","GO:0003677//DNA binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0003714//transcription corepressor activity;GO:0042802//identical protein binding;GO:0019901//protein kinase binding;GO:0003682//chromatin binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0001047//core promoter binding","GO:0038061//NIK/NF-kappaB signaling;GO:0034097//response to cytokine;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0032922//circadian regulation of gene expression;GO:0045087//innate immune response;GO:0019882//antigen processing and presentation;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0006351//transcription, DNA-templated;GO:0006954//inflammatory response;GO:0045063//T-helper 1 cell differentiation;GO:0071470//cellular response to osmotic stress;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0032688//negative regulation of interferon-beta production;GO:0043011//myeloid dendritic cell differentiation","K09253//transcription factor RelB","NP_006500.2//transcription factor RelB [Homo sapiens]","3//A2MP1"]
[64135,3617,0.18,0.5,1.47393118833241,0.0185279031054227,"*",0.00688736,"IFIH1","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0004386//helicase activity;GO:0003725//double-stranded RNA binding;GO:0016787//hydrolase activity;GO:0008270//zinc ion binding;GO:0043021//ribonucleoprotein complex binding;GO:0003727//single-stranded RNA binding","GO:0016925//protein sumoylation;GO:0060760//positive regulation of response to cytokine stimulus;GO:0035549//positive regulation of interferon-beta secretion;GO:0016579//protein deubiquitination;GO:0045087//innate immune response;GO:0039530//MDA-5 signaling pathway;GO:2000778//positive regulation of interleukin-6 secretion;GO:0039528//cytoplasmic pattern recognition receptor signaling pathway in response to virus;GO:0032728//positive regulation of interferon-beta production;GO:0009597//detection of virus;GO:0071360//cellular response to exogenous dsRNA;GO:0051607//defense response to virus;GO:0032727//positive regulation of interferon-alpha production;GO:0016032//viral process;GO:0034344//regulation of type III interferon production;GO:1904469//positive regulation of tumor necrosis factor secretion;GO:1902741//positive regulation of interferon-alpha secretion;GO:0032480//negative regulation of type I interferon production;GO:0009615//response to virus","K12647//interferon-induced helicase C domain-containing protein 1 [EC:3.6.4.13]","NP_071451.2//interferon-induced helicase C domain-containing protein 1 [Homo sapiens]","3//A2MP1"]
[29950,1213,17.96,49.65,1.46700636767459,{"v":3.66637480174672e-50,"d":"3.67E-50"},"Up",{"v":5.25604e-52,"d":"5.26E-52"},"SERTAD1","GO:0005634//nucleus;GO:0005737//cytoplasm","NA","GO:0030308//negative regulation of cell growth;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0008284//positive regulation of cell proliferation","NA","NP_037508.2//SERTA domain-containing protein 1 [Homo sapiens]","3//A2MP1"]
[100131378,903,0.83,2.29,1.46416435675002,0.0161148471991772,"*",0.00588544,"C11orf91","GO:0043231//intracellular membrane-bounded organelle","NA","NA","K00894//ethanolamine kinase [EC:2.7.1.82];K10367//formin 1","NP_001160164.1//uncharacterized protein C11orf91 [Homo sapiens]","1//3"]
[340061,1960,0.49,1.35,1.46210575293562,0.00118791928779198,"*",0.000337472,"TMEM173","GO:0030667//secretory granule membrane;GO:0005654//nucleoplasm;GO:0005777//peroxisome;GO:0005741//mitochondrial outer membrane;GO:0048471//perinuclear region of cytoplasm;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0030659//cytoplasmic vesicle membrane","GO:0042802//identical protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0035438//cyclic-di-GMP binding;GO:0008134//transcription factor binding;GO:0042803//protein homodimerization activity;GO:0061507//cyclic-GMP-AMP binding;GO:0019901//protein kinase binding","GO:0032481//positive regulation of type I interferon production;GO:0032479//regulation of type I interferon production;GO:0002218//activation of innate immune response;GO:0032092//positive regulation of protein binding;GO:0035458//cellular response to interferon-beta;GO:0071407//cellular response to organic cyclic compound;GO:0043312//neutrophil degranulation;GO:0045087//innate immune response;GO:0033160//positive regulation of protein import into nucleus, translocation;GO:0071360//cellular response to exogenous dsRNA;GO:0051607//defense response to virus;GO:0016032//viral process;GO:0006915//apoptotic process;GO:0032608//interferon-beta production;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0002230//positive regulation of defense response to virus by host;GO:0042993//positive regulation of transcription factor import into nucleus","K12654//transmembrane protein 173","NP_001288667.1//stimulator of interferon genes protein isoform 2 [Homo sapiens];NP_938023.1//stimulator of interferon genes protein isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[54625,7713,3.94,10.85,1.46142750787547,{"v":1.27924158992806E-71,"d":"1.28E-71"},"Up",{"v":1.11315E-73,"d":"1.11E-73"},"PARP14","GO:0016020//membrane;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0070403//NAD+ binding;GO:0003950//NAD+ ADP-ribosyltransferase activity;GO:0019899//enzyme binding","GO:0006355//regulation of transcription, DNA-templated;GO:0060336//negative regulation of interferon-gamma-mediated signaling pathway;GO:0006351//transcription, DNA-templated;GO:0070212//protein poly-ADP-ribosylation;GO:0010629//negative regulation of gene expression;GO:0042532//negative regulation of tyrosine phosphorylation of STAT protein;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:1902216//positive regulation of interleukin-4-mediated signaling pathway;GO:0006471//protein ADP-ribosylation","K15261//poly [ADP-ribose] polymerase 10/14/15 [EC:2.4.2.30]","NP_060024.2//poly [ADP-ribose] polymerase 14 [Homo sapiens]","2//1"]
[129881,2187,0.04,0.11,1.4594316186373,0.531268036302162,"*",0.37379,"CCDC173","NA","NA","NA","K00476//aspartate beta-hydroxylase [EC:1.14.11.16]","NP_001078916.1//coiled-coil domain-containing protein 173 [Homo sapiens]","1//3"]
[8817,1999,0.16,0.44,1.4594316186373,0.150176893409035,"*",0.0761696,"FGF18","GO:0005730//nucleolus;GO:0005576//extracellular region","GO:0008083//growth factor activity;GO:0005111//type 2 fibroblast growth factor receptor binding;GO:0005105//type 1 fibroblast growth factor receptor binding","GO:0030324//lung development;GO:0001958//endochondral ossification;GO:0001525//angiogenesis;GO:0043406//positive regulation of MAP kinase activity;GO:0030949//positive regulation of vascular endothelial growth factor receptor signaling pathway;GO:0002063//chondrocyte development;GO:0001957//intramembranous ossification;GO:0032332//positive regulation of chondrocyte differentiation;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:2000546//positive regulation of endothelial cell chemotaxis to fibroblast growth factor;GO:0008284//positive regulation of cell proliferation","K04358//fibroblast growth factor","XP_014956713.1//PREDICTED: fibroblast growth factor 18 isoform X2 [Ovis aries]","2//1"]
[51296,2134,0.04,0.11,1.4594316186373,0.531031791177517,"*",0.37379,"SLC15A3","GO:0005765//lysosomal membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane","GO:0015333//peptide:proton symporter activity;GO:0005215//transporter activity","GO:0015031//protein transport;GO:0006811//ion transport","K14638//solute carrier family 15 (peptide/histidine transporter), member 3/4","NP_057666.1//solute carrier family 15 member 3 [Homo sapiens]","2//1"]
[633,2470,0.04,0.11,1.4594316186373,0.530183045640206,"*",0.37379,"BGN","GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0005737//cytoplasm;GO:0005578//proteinaceous extracellular matrix;GO:0005796//Golgi lumen;GO:0009986//cell surface;GO:0030133//transport vesicle;GO:0042383//sarcolemma;GO:0005576//extracellular region;GO:0043202//lysosomal lumen","GO:0005201//extracellular matrix structural constituent;GO:0004860//protein kinase inhibitor activity;GO:0005539//glycosaminoglycan binding;GO:0050840//extracellular matrix binding","GO:0019800//peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan;GO:0046426//negative regulation of JAK-STAT cascade;GO:0030208//dermatan sulfate biosynthetic process;GO:0030206//chondroitin sulfate biosynthetic process;GO:0001974//blood vessel remodeling;GO:0006469//negative regulation of protein kinase activity;GO:0030198//extracellular matrix organization;GO:0030207//chondroitin sulfate catabolic process;GO:0019221//cytokine-mediated signaling pathway;GO:0030203//glycosaminoglycan metabolic process","K08118//biglycan","XP_011857624.1//PREDICTED: biglycan isoform X1 [Mandrillus leucophaeus]",5]
[149297,2252,0.04,0.11,1.4594316186373,0.52952478361121,"*",0.37379,"FAM78B","NA","NA","NA","K17943//pumilio RNA-binding family","XP_008683918.1//PREDICTED: protein FAM78B [Ursus maritimus];XP_017454519.1//PREDICTED: LOW QUALITY PROTEIN: protein FAM78B isoform X1 [Rattus norvegicus]","4;1//3"]
[1613,2329,9.34,25.62,1.45577602063198,{"v":3.93973012695652e-50,"d":"3.94E-50"},"Up",{"v":5.67258e-52,"d":"5.67E-52"},"DAPK3","GO:0005884//actin filament;GO:0016605//PML body;GO:0005634//nucleus;GO:0045121//membrane raft;GO:0005737//cytoplasm","GO:0017048//Rho GTPase binding;GO:0008140//cAMP response element binding protein binding;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0008022//protein C-terminus binding;GO:0004674//protein serine/threonine kinase activity;GO:0043522//leucine zipper domain binding","GO:0007346//regulation of mitotic cell cycle;GO:0030335//positive regulation of cell migration;GO:0006355//regulation of transcription, DNA-templated;GO:0097190//apoptotic signaling pathway;GO:0035556//intracellular signal transduction;GO:0007088//regulation of mitotic nuclear division;GO:0071346//cellular response to interferon-gamma;GO:0051893//regulation of focal adhesion assembly;GO:0043065//positive regulation of apoptotic process;GO:0017148//negative regulation of translation;GO:0010506//regulation of autophagy;GO:0030182//neuron differentiation;GO:0006468//protein phosphorylation;GO:0006351//transcription, DNA-templated;GO:0008360//regulation of cell shape;GO:2000145//regulation of cell motility;GO:0006940//regulation of smooth muscle contraction;GO:0006915//apoptotic process;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0046777//protein autophosphorylation;GO:2000249//regulation of actin cytoskeleton reorganization;GO:0018107//peptidyl-threonine phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0016569//covalent chromatin modification;GO:2001241//positive regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0043519//regulation of myosin II filament organization;GO:0042981//regulation of apoptotic process","K08803//death-associated protein kinase [EC:2.7.11.1]","XP_012291390.1//death-associated protein kinase 3 isoform X1 [Aotus nancymaae]","2//1"]
[64170,2032,0.15,0.41,1.45066140900957,0.150084271666461,"*",0.0761696,"CARD9","GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0050700//CARD domain binding;GO:0042803//protein homodimerization activity","GO:0032494//response to peptidoglycan;GO:0046330//positive regulation of JNK cascade;GO:0032755//positive regulation of interleukin-6 production;GO:0009620//response to fungus;GO:0042534//regulation of tumor necrosis factor biosynthetic process;GO:0043330//response to exogenous dsRNA;GO:0032760//positive regulation of tumor necrosis factor production;GO:0050830//defense response to Gram-positive bacterium;GO:0045087//innate immune response;GO:0045408//regulation of interleukin-6 biosynthetic process;GO:0045076//regulation of interleukin-2 biosynthetic process;GO:0042493//response to drug;GO:0032495//response to muramyl dipeptide;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0051607//defense response to virus;GO:0032874//positive regulation of stress-activated MAPK cascade;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0042981//regulation of apoptotic process","K12794//caspase recruitment domain-containing protein 9","XP_011723066.1//PREDICTED: caspase recruitment domain-containing protein 9 isoform X1 [Macaca nemestrina]","4;3//A2MP1"]
[6758,1308,0.26,0.71,1.44930740136359,0.150195431477595,"*",0.0761696,"SSX5","GO:0005634//nucleus","GO:0003714//transcription corepressor activity;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:1903507//negative regulation of nucleic acid-templated transcription","K15625//protein SSX2;K15624//protein SSX1","XP_015299131.1//PREDICTED: protein SSX3 isoform X2 [Macaca fascicularis];AAC05821.1//SSX5 [Homo sapiens]","1//3;3//A2MP1"]
[3759,5397,0.35,0.95,1.44057259138598,{"v":4.78065153863767e-05,"d":"4.78E-05"},"Up",{"v":1.045674E-5,"d":"1.05E-05"},"KCNJ2","NA","NA","NA","K04996//potassium inwardly-rectifying channel subfamily J member 2","ELK12419.1//Inward rectifier potassium channel 2 [Pteropus alecto]","2//1"]
[100526737,923,7.6,20.62,1.43997300903716,{"v":6.81241949230769e-16,"d":"6.81E-16"},"Up",{"v":4.43528e-17,"d":"4.44E-17"},"RBM14-RBM4","NA","GO:0003723//RNA binding;GO:0008270//zinc ion binding","NA","K13187//RNA-binding protein 4;K13189//RNA-binding protein 14","NP_001185774.1//RBM14-RBM4 protein isoform 1 [Homo sapiens];NP_001185775.1//RBM14-RBM4 protein isoform 2 [Homo sapiens]","1//3"]
[30008,2096,0.34,0.92,1.43609911480667,0.0232612613883432,"*",8.89444E-3,"EFEMP2","NA","NA","NA","K19866//EGF-containing fibulin-like extracellular matrix protein 2","XP_011897030.1//PREDICTED: EGF-containing fibulin-like extracellular matrix protein 2 isoform X1 [Cercocebus atys]",4]
[25876,1597,0.3,0.81,1.43295940727611,0.0764171738875715,"*",0.0342954,"SPEF1","GO:0031514//motile cilium;GO:0005737//cytoplasm;GO:0005930//axoneme","GO:0008017//microtubule binding","GO:0016477//cell migration;GO:0007026//negative regulation of microtubule depolymerization","K19720//collagen, type III, alpha","NP_056232.2//sperm flagellar protein 1 [Homo sapiens]",4]
[27289,1665,7.56,20.4,1.43211101263779,{"v":7.53035928270042e-28,"d":"7.53E-28"},"Up",{"v":2.2345e-29,"d":"2.23E-29"},"RND1","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005622//intracellular;GO:0005737//cytoplasm;GO:0005912//adherens junction;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0005886//plasma membrane","GO:0005102//receptor binding;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0007015//actin filament organization;GO:0007264//small GTPase mediated signal transduction;GO:0007162//negative regulation of cell adhesion;GO:0016322//neuron remodeling","K07531//Rho family GTPase 1","NP_055285.1//rho-related GTP-binding protein Rho6 precursor [Homo sapiens]","3//A2MP1"]
[59335,2492,0.13,0.35,1.42884329880387,0.150213974123457,"*",0.0761696,"PRDM12","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_007453202.1//PREDICTED: PR domain zinc finger protein 12 [Lipotes vexillifer]","2//1"]
[92797,3621,0.35,0.94,1.42530583473267,1.33684724159021E-3,"*",3.83128E-4,"HELB","GO:0035861//site of double-strand break;GO:0005634//nucleus;GO:0005658//alpha DNA polymerase:primase complex;GO:0005662//DNA replication factor A complex;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0004004//ATP-dependent RNA helicase activity;GO:0005524//ATP binding;GO:0017116//single-stranded DNA-dependent ATP-dependent DNA helicase activity;GO:0043141//ATP-dependent 5'-3' DNA helicase activity","GO:0006396//RNA processing;GO:1903775//regulation of DNA double-strand break processing;GO:2000042//negative regulation of double-strand break repair via homologous recombination;GO:0006269//DNA replication, synthesis of RNA primer;GO:0006281//DNA repair;GO:0006260//DNA replication;GO:0006974//cellular response to DNA damage stimulus","K15254//DNA helicase B [EC:3.6.4.12]","NP_387467.2//DNA helicase B [Homo sapiens]",4]
[1490,2358,8.24,22.08,1.42202392959495,{"v":2.71483301438849E-42,"d":"2.71E-42"},"Up",{"v":4.7247e-44,"d":"4.72E-44"},"CTGF","GO:0043231//intracellular membrane-bounded organelle;GO:0005615//extracellular space;GO:0005938//cell cortex;GO:0005801//cis-Golgi network;GO:0005578//proteinaceous extracellular matrix;GO:0048471//perinuclear region of cytoplasm;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0005520//insulin-like growth factor binding;GO:0008083//growth factor activity;GO:0008022//protein C-terminus binding;GO:0005178//integrin binding;GO:0001968//fibronectin binding;GO:0008201//heparin binding","GO:0046330//positive regulation of JNK cascade;GO:0016477//cell migration;GO:0034059//response to anoxia;GO:0032967//positive regulation of collagen biosynthetic process;GO:0032355//response to estradiol;GO:0009749//response to glucose;GO:0019216//regulation of lipid metabolic process;GO:0001502//cartilage condensation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0045597//positive regulation of cell differentiation;GO:0009611//response to wounding;GO:0051385//response to mineralocorticoid;GO:0001558//regulation of cell growth;GO:0050867//positive regulation of cell activation;GO:0001525//angiogenesis;GO:0030154//cell differentiation;GO:0072593//reactive oxygen species metabolic process;GO:0010628//positive regulation of gene expression;GO:0007160//cell-matrix adhesion;GO:0007155//cell adhesion;GO:0008544//epidermis development;GO:0071897//DNA biosynthetic process;GO:0032330//regulation of chondrocyte differentiation;GO:0070542//response to fatty acid;GO:0060401//cytosolic calcium ion transport;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0030324//lung development;GO:0043200//response to amino acid;GO:0035556//intracellular signal transduction;GO:0010629//negative regulation of gene expression;GO:0001503//ossification;GO:0007229//integrin-mediated signaling pathway;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0070318//positive regulation of G0 to G1 transition;GO:0043434//response to peptide hormone;GO:0007267//cell-cell signaling;GO:0060452//positive regulation of cardiac muscle contraction;GO:0001894//tissue homeostasis;GO:0007568//aging;GO:0035988//chondrocyte proliferation;GO:0051496//positive regulation of stress fiber assembly;GO:0070278//extracellular matrix constituent secretion;GO:0060548//negative regulation of cell death;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0008284//positive regulation of cell proliferation","K06827//connective tissue growth factor","NP_001892.1//connective tissue growth factor precursor [Homo sapiens]","2//1"]
[3552,2947,0.03,0.08,1.41503749927884,0.531551808065521,"*",0.37379,"IL1A","GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005576//extracellular region","GO:0005125//cytokine activity;GO:0005507//copper ion binding;GO:0005149//interleukin-1 receptor binding","GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0032755//positive regulation of interleukin-6 production;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0010575//positive regulation of vascular endothelial growth factor production;GO:0051781//positive regulation of cell division;GO:0070498//interleukin-1-mediated signaling pathway;GO:0071639//positive regulation of monocyte chemotactic protein-1 production;GO:0008283//cell proliferation;GO:0035234//ectopic germ cell programmed cell death;GO:0045766//positive regulation of angiogenesis;GO:0045840//positive regulation of mitotic nuclear division;GO:0008285//negative regulation of cell proliferation;GO:0001660//fever generation;GO:0046688//response to copper ion;GO:0010628//positive regulation of gene expression;GO:0034605//cellular response to heat;GO:0006915//apoptotic process;GO:0006954//inflammatory response;GO:0050714//positive regulation of protein secretion;GO:2000391//positive regulation of neutrophil extravasation;GO:0045086//positive regulation of interleukin-2 biosynthetic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006955//immune response;GO:0019221//cytokine-mediated signaling pathway;GO:0050715//positive regulation of cytokine secretion;GO:0002248//connective tissue replacement involved in inflammatory response wound healing","K04383//interleukin 1 alpha","NP_000566.3//interleukin-1 alpha precursor [Homo sapiens]",4]
[27111,1484,0.06,0.16,1.41503749927884,0.53150449172156,"*",0.37379,"SDCBP2","GO:0070062//extracellular exosome;GO:0005730//nucleolus;GO:0016607//nuclear speck;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0008022//protein C-terminus binding;GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding","GO:0007399//nervous system development;GO:0046907//intracellular transport;GO:0008283//cell proliferation;GO:0035556//intracellular signal transduction","K17254//syntenin-1","NP_536737.3//syntenin-2 isoform a [Homo sapiens]","4;1//3;5"]
[2001,2039,0.06,0.16,1.41503749927884,0.531409884300463,"*",0.37379,"ELF5","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0030154//cell differentiation;GO:0060644//mammary gland epithelial cell differentiation;GO:0045596//negative regulation of cell differentiation;GO:0001712//ectodermal cell fate commitment;GO:0035019//somatic stem cell population maintenance;GO:0006366//transcription from RNA polymerase II promoter","K17101//E74-like factor 5","NP_001230010.1//ETS-related transcription factor Elf-5 isoform 4 [Homo sapiens];EPQ06656.1//ETS-related transcription factor Elf-5 [Myotis brandtii];NP_938195.1//ETS-related transcription factor Elf-5 isoform 1 [Homo sapiens];NP_001230009.1//ETS-related transcription factor Elf-5 isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[63950,3083,0.03,0.08,1.41503749927884,0.531126264009963,"*",0.37379,"DMRTA2","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0043565//sequence-specific DNA binding;GO:0046982//protein heterodimerization activity;GO:0003700//DNA binding transcription factor activity;GO:0042803//protein homodimerization activity","GO:0035914//skeletal muscle cell differentiation;GO:0021796//cerebral cortex regionalization;GO:0048665//neuron fate specification;GO:0071542//dopaminergic neuron differentiation;GO:0002052//positive regulation of neuroblast proliferation;GO:0007420//brain development","K19491//doublesex- and mab-3-related transcription factor 4/5","NP_115486.1//doublesex- and mab-3-related transcription factor A2 [Homo sapiens]","2//1"]
[9381,6345,0.03,0.08,1.41503749927884,0.43423267743459,"*",0.287794,"OTOF","GO:0016323//basolateral plasma membrane;GO:0030672//synaptic vesicle membrane;GO:0005829//cytosol;GO:0098793//presynapse;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0005789//endoplasmic reticulum membrane","GO:0005509//calcium ion binding","GO:0016079//synaptic vesicle exocytosis;GO:0061025//membrane fusion;GO:0007605//sensory perception of sound","K19949//otoferlin","NP_919303.1//otoferlin isoform c [Homo sapiens];NP_919224.1//otoferlin isoform a [Homo sapiens];XP_016860827.1//PREDICTED: otoferlin isoform X1 [Homo sapiens];NP_001274418.1//otoferlin isoform e [Homo sapiens];XP_016803687.1//PREDICTED: otoferlin isoform X4 [Pan troglodytes]","1//3;3//A2MP1;2//1"]
[6757,1456,0.21,0.56,1.41503749927884,0.175867577694989,"*",0.091611,"SSX2","GO:0005634//nucleus","GO:0003714//transcription corepressor activity;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:1903507//negative regulation of nucleic acid-templated transcription","K15625//protein SSX2;K15624//protein SSX1","XP_011925496.1//PREDICTED: protein SSX2 isoform X2 [Cercocebus atys];NP_003138.3//protein SSX2 isoform a [Homo sapiens];XP_009437384.2//PREDICTED: protein SSX2 isoform X2 [Pan troglodytes]","1//3;2//1;5"]
[6853,3172,0.03,0.08,1.41503749927884,0.530607079001155,"*",0.37379,"SYN1","GO:0030425//dendrite;GO:0048786//presynaptic active zone;GO:0008021//synaptic vesicle;GO:0043209//myelin sheath;GO:0030054//cell junction;GO:0043195//terminal bouton;GO:0014069//postsynaptic density;GO:0098993//anchored component of synaptic vesicle membrane;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0000795//synaptonemal complex","GO:0003779//actin binding;GO:0005524//ATP binding;GO:0003824//catalytic activity;GO:0048306//calcium-dependent protein binding;GO:0005215//transporter activity;GO:0019901//protein kinase binding","GO:2000300//regulation of synaptic vesicle exocytosis;GO:0007269//neurotransmitter secretion;GO:0007268//chemical synaptic transmission;GO:0097091//synaptic vesicle clustering;GO:0046928//regulation of neurotransmitter secretion","K19941//synapsin","NP_008881.2//synapsin-1 isoform Ia [Homo sapiens];NP_598006.1//synapsin-1 isoform Ib [Homo sapiens]","3//A2MP1;2//1"]
[221692,2462,0.06,0.16,1.41503749927884,0.434068676801057,"*",0.287794,"PHACTR1","GO:0005634//nucleus;GO:0005829//cytosol;GO:0030054//cell junction;GO:0045202//synapse","GO:0003779//actin binding;GO:0004864//protein phosphatase inhibitor activity;GO:0008157//protein phosphatase 1 binding","GO:0031032//actomyosin structure organization;GO:0031532//actin cytoskeleton reorganization;GO:0048870//cell motility;GO:0043149//stress fiber assembly","K17594//phosphatase and actin regulator 3","NP_001309243.1//phosphatase and actin regulator 1 isoform e [Homo sapiens];EAW55321.1//phosphatase and actin regulator 1, isoform CRA_b [Homo sapiens];XP_021792295.1//phosphatase and actin regulator 1 isoform X8 [Papio anubis];XP_021792287.1//phosphatase and actin regulator 1 isoform X2 [Papio anubis]","1//3;3//A2MP1;2//1"]
[6503,2872,0.03,0.08,1.41503749927884,0.53027721669627,"*",0.37379,"SLA","GO:0005768//endosome;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane","GO:0005070//SH3/SH2 adaptor activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005102//receptor binding","GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0016477//cell migration;GO:0038083//peptidyl-tyrosine autophosphorylation;GO:0030154//cell differentiation;GO:0042127//regulation of cell proliferation;GO:0045087//innate immune response","K08890//B lymphoid tyrosine kinase [EC:2.7.10.2];K08893//hemopoietic cell kinase [EC:2.7.10.2]","NP_001039022.2//src-like-adapter isoform b [Homo sapiens];XP_008953704.1//PREDICTED: src-like-adapter isoform X1 [Pan paniscus];NP_006739.2//src-like-adapter isoform c [Homo sapiens];NP_001269893.1//src-like-adapter isoform d [Homo sapiens]","1//3;3//A2MP1;2//1"]
[728464,2780,0.12,0.32,1.41503749927884,0.150065761026147,"*",0.0761696,"METTL24","GO:0005576//extracellular region","GO:0008168//methyltransferase activity","NA","K12816//pre-mRNA-processing factor 17","NP_001116836.1//methyltransferase-like protein 24 isoform 1 precursor [Homo sapiens]","1//3;2//1"]
[4121,5044,0.03,0.08,1.41503749927884,0.433945757598641,"*",0.287794,"MAN1A1","GO:0070062//extracellular exosome;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0000139//Golgi membrane","GO:0004571//mannosyl-oligosaccharide 1,2-alpha-mannosidase activity;GO:0005509//calcium ion binding","GO:0006491//N-glycan processing","K01230//mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]","XP_005267043.1//PREDICTED: mannosyl-oligosaccharide 1,2-alpha-mannosidase IA isoform X1 [Homo sapiens]","3//A2MP1"]
[136332,3147,0.03,0.08,1.41503749927884,0.52943087958858,"*",0.37379,"LRGUK","GO:0042995//cell projection;GO:0002177//manchette;GO:0001669//acrosomal vesicle","GO:0005524//ATP binding;GO:0016301//kinase activity","GO:0030154//cell differentiation;GO:0035082//axoneme assembly;GO:0007283//spermatogenesis","K17550//protein phosphatase 1 regulatory subunit 7","NP_653249.1//leucine-rich repeat and guanylate kinase domain-containing protein [Homo sapiens]","2//1"]
[10870,524,0.5,1.33,1.41142624572647,0.25531330793301,"*",0.1450622,"HCST","GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0043548//phosphatidylinositol 3-kinase binding;GO:0005102//receptor binding","GO:0006468//protein phosphorylation;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0050776//regulation of immune response","K07988//hematopoietic cell signal transducer","NP_055081.1//hematopoietic cell signal transducer isoform 1 precursor [Homo sapiens];NP_001007470.1//hematopoietic cell signal transducer isoform 2 precursor [Homo sapiens]","1//3;3//A2MP1"]
[9244,1824,0.4,1.06,1.40599235967584,0.0232650703389553,"*",8.89444E-3,"CRLF1","GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005576//extracellular region;GO:0097058//CRLF-CLCF1 complex","GO:0019955//cytokine binding;GO:0046982//protein heterodimerization activity","GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0043524//negative regulation of neuron apoptotic process;GO:0001657//ureteric bud development;GO:0010469//regulation of receptor activity;GO:2000672//negative regulation of motor neuron apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0035722//interleukin-12-mediated signaling pathway","K05060//interleukin 6 signal transducer;K05081//prolactin receptor","NP_004741.1//cytokine receptor-like factor 1 precursor [Homo sapiens]",4]
[119391,879,0.57,1.51,1.40551472516034,0.0211761817019868,"*",0.00800702,"GSTO2","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0004364//glutathione transferase activity;GO:0050610//methylarsonate reductase activity;GO:0042802//identical protein binding;GO:0045174//glutathione dehydrogenase (ascorbate) activity;GO:0016491//oxidoreductase activity","GO:0019852//L-ascorbic acid metabolic process;GO:0006749//glutathione metabolic process;GO:0009407//toxin catabolic process;GO:0006805//xenobiotic metabolic process;GO:0071243//cellular response to arsenic-containing substance;GO:0055114//oxidation-reduction process;GO:1901687//glutathione derivative biosynthetic process","K00799//glutathione S-transferase [EC:2.5.1.18]","NP_001177942.1//glutathione S-transferase omega-2 isoform 2 [Homo sapiens];AAO23573.1//glutathione transferase omega 2, partial [Homo sapiens];NP_899062.1//glutathione S-transferase omega-2 isoform 1 [Homo sapiens]","1//3"]
[9022,813,0.62,1.64,1.40335569423121,0.076427834765625,"*",0.0342954,"CLIC3","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0016604//nuclear body;GO:0034707//chloride channel complex;GO:0005737//cytoplasm","GO:0005244//voltage-gated ion channel activity;GO:0005254//chloride channel activity","GO:0007165//signal transduction;GO:0006821//chloride transport;GO:1902476//chloride transmembrane transport","K05023//chloride intracellular channel protein 3","NP_004660.2//chloride intracellular channel protein 3 [Homo sapiens]","2//1"]
[90634,1309,0.14,0.37,1.40209844357135,0.496207692782569,"*",0.342164,"N4BP2L1","NA","NA","NA","K15720//NEDD4-binding protein 2 [EC:3.-.-.-]","XP_016780635.1//PREDICTED: NEDD4-binding protein 2-like 1 isoform X5 [Pan troglodytes];XP_016780631.1//PREDICTED: NEDD4-binding protein 2-like 1 isoform X2 [Pan troglodytes];XP_016780634.1//PREDICTED: NEDD4-binding protein 2-like 1 isoform X4 [Pan troglodytes];XP_016780636.1//PREDICTED: NEDD4-binding protein 2-like 1 isoform X6 [Pan troglodytes];XP_001143836.3//PREDICTED: NEDD4-binding protein 2-like 1 isoform X1 [Pan troglodytes];XP_016780633.1//PREDICTED: NEDD4-binding protein 2-like 1 isoform X3 [Pan troglodytes];NP_001340557.1//NEDD4-binding protein 2-like 1 isoform 6 [Homo sapiens];XP_015294621.1//PREDICTED: NEDD4-binding protein 2-like 1 isoform X5 [Macaca fascicularis];XP_018895199.1//PREDICTED: NEDD4-binding protein 2-like 1 isoform X2 [Gorilla gorilla gorilla];NP_001340556.1//NEDD4-binding protein 2-like 1 isoform 5 [Homo sapiens];NP_001340560.1//NEDD4-binding protein 2-like 1 isoform 9 [Homo sapiens]","1//3;2//1"]
[27010,2462,0.14,0.37,1.40209844357135,0.150121306650216,"*",0.0761696,"TPK1","GO:0005829//cytosol","GO:0030975//thiamine binding;GO:0004788//thiamine diphosphokinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity","GO:0042723//thiamine-containing compound metabolic process;GO:0006772//thiamine metabolic process;GO:0009229//thiamine diphosphate biosynthetic process","K00949//thiamine pyrophosphokinase [EC:2.7.6.2]","XP_015426472.1//PREDICTED: thiamin pyrophosphokinase 1 isoform X3 [Myotis davidii];NP_001035947.1//thiamin pyrophosphokinase 1 isoform b [Homo sapiens];NP_001337812.1//thiamin pyrophosphokinase 1 isoform d [Homo sapiens];NP_001337810.1//thiamin pyrophosphokinase 1 isoform c [Homo sapiens];XP_012302990.1//thiamin pyrophosphokinase 1 isoform X1 [Aotus nancymaae];XP_021520956.1//thiamin pyrophosphokinase 1 isoform X2 [Aotus nancymaae];XP_011514333.1//PREDICTED: thiamin pyrophosphokinase 1 isoform X1 [Homo sapiens]","1//3;3//A2MP1"]
[79094,1487,7.83,20.6,1.39556012477954,{"v":2.69215692786325e-24,"d":"2.69E-24"},"Up",{"v":9.85922e-26,"d":"9.86E-26"},"CHAC1","GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005802//trans-Golgi network","GO:0003839//gamma-glutamylcyclotransferase activity;GO:0016829//lyase activity;GO:0005112//Notch binding","GO:0006986//response to unfolded protein;GO:0010955//negative regulation of protein processing;GO:0022008//neurogenesis;GO:0006751//glutathione catabolic process;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0045746//negative regulation of Notch signaling pathway;GO:0007219//Notch signaling pathway;GO:0006750//glutathione biosynthetic process","K07232//cation transport protein ChaC","NP_077016.2//glutathione-specific gamma-glutamylcyclotransferase 1 isoform a [Homo sapiens];NP_001136248.1//glutathione-specific gamma-glutamylcyclotransferase 1 isoform b [Homo sapiens]","3//A2MP1;5"]
[5699,1019,12.76,33.5,1.39253276646763,{"v":2.25388186821705E-26,"d":"2.25E-26"},"Up",{"v":7.2806e-28,"d":"7.28E-28"},"PSMB10","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000502//proteasome complex;GO:1990111//spermatoproteasome complex;GO:0005737//cytoplasm;GO:0005839//proteasome core complex;GO:0005829//cytosol;GO:0019774//proteasome core complex, beta-subunit complex","GO:0004298//threonine-type endopeptidase activity","GO:0043687//post-translational protein modification;GO:0038061//NIK/NF-kappaB signaling;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0006521//regulation of cellular amino acid metabolic process;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition;GO:0006959//humoral immune response;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0016579//protein deubiquitination;GO:0043488//regulation of mRNA stability;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0000209//protein polyubiquitination;GO:0000902//cell morphogenesis;GO:0055085//transmembrane transport;GO:0000165//MAPK cascade;GO:0050852//T cell receptor signaling pathway;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0016032//viral process;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0042098//T cell proliferation;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:1902036//regulation of hematopoietic stem cell differentiation","K02733//20S proteasome subunit beta 10 [EC:3.4.25.1]","NP_002792.1//proteasome subunit beta type-10 precursor [Homo sapiens]","3//A2MP1"]
[100271927,2794,0.52,1.36,1.38702312310925,0.000994973427230047,"Up",0.00027861,"RASA4B","GO:0005829//cytosol;GO:0005622//intracellular;GO:0031235//intrinsic component of the cytoplasmic side of the plasma membrane","GO:0046872//metal ion binding;GO:0005096//GTPase activator activity","GO:0046580//negative regulation of Ras protein signal transduction;GO:0000165//MAPK cascade;GO:0071277//cellular response to calcium ion;GO:0035556//intracellular signal transduction;GO:0034260//negative regulation of GTPase activity","K17630//Ras GTPase-activating protein 4","NP_001264264.1//ras GTPase-activating protein 4B [Homo sapiens]","1//3"]
[255488,5036,0.05,0.13,1.37851162325373,0.255341441630854,"*",0.1450622,"RNF144B","NA","NA","NA","K11975//E3 ubiquitin-protein ligase RNF144 [EC:2.3.2.27]","CAD38622.1//hypothetical protein, partial [Homo sapiens]","3//A2MP1"]
[148103,3115,0.1,0.26,1.37851162325373,0.216492992807746,"*",0.1175844,"ZNF599","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_003997989.1//PREDICTED: zinc finger protein 599 isoform X1 [Felis catus]","2//1"]
[286527,1809,0.82,2.13,1.37715761560775,0.226319080358969,"*",0.1247206,"TMSB15B","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein;K01368//cathepsin S [EC:3.4.22.27];K11252//histone H2B;K05764//thymosin, beta 4","XP_009235141.1//PREDICTED: thymosin beta-15A isoform X1 [Pongo abelii];XP_002930139.2//PREDICTED: thymosin beta-15A [Ailuropoda melanoleuca];XP_011890510.1//PREDICTED: ras-related protein Rab-9B isoform X1 [Cercocebus atys]","1//3;3//A2MP1"]
[388555,662,0.64,1.66,1.37503943134692,0.128463193614304,"*",0.062969,"IGFL3","GO:0005615//extracellular space","GO:0005102//receptor binding","NA","NA","NP_997276.1//insulin growth factor-like family member 3 precursor [Homo sapiens]","1//3"]
[127544,2692,9.76,25.26,1.37190158622467,{"v":5.6279984953271e-52,"d":"5.63E-52"},"Up",{"v":7.5397e-54,"d":"7.54E-54"},"RNF19B","GO:0000151//ubiquitin ligase complex;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0044194//cytolytic granule;GO:0005789//endoplasmic reticulum membrane","GO:0061630//ubiquitin protein ligase activity;GO:0046872//metal ion binding;GO:0004842//ubiquitin-protein transferase activity;GO:0031624//ubiquitin conjugating enzyme binding","GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0000209//protein polyubiquitination;GO:0002250//adaptive immune response","K11973//E3 ubiquitin-protein ligase RNF19B [EC:2.3.2.27]","NP_001287755.1//E3 ubiquitin-protein ligase RNF19B isoform c [Homo sapiens];NP_699172.2//E3 ubiquitin-protein ligase RNF19B isoform a [Homo sapiens];NP_001120833.1//E3 ubiquitin-protein ligase RNF19B isoform b [Homo sapiens]","1//3;3//A2MP1;2//1"]
[597,899,2.75,7.08,1.36431774167098,{"v":1.63876613898411e-05,"d":"1.64E-05"},"Up",{"v":3.2921e-06,"d":"3.29E-06"},"BCL2A1","GO:0005741//mitochondrial outer membrane","GO:0046982//protein heterodimerization activity;GO:0051400//BH domain binding;GO:0042803//protein homodimerization activity;GO:0015267//channel activity","GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0043066//negative regulation of apoptotic process;GO:0007568//aging;GO:0008053//mitochondrial fusion;GO:0043065//positive regulation of apoptotic process;GO:0021987//cerebral cortex development;GO:0001836//release of cytochrome c from mitochondria","K02162//hematopoietic Bcl-2-related protein A1","NP_001108207.1//bcl-2-related protein A1 isoform 2 [Homo sapiens];NP_004040.1//bcl-2-related protein A1 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[9148,4315,0.07,0.18,1.36257007938471,0.216542910491123,"*",0.1175844,"NEURL1","GO:0043197//dendritic spine;GO:0097440//apical dendrite;GO:0014069//postsynaptic density;GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0043204//perikaryon","GO:0061630//ubiquitin protein ligase activity;GO:0045183//translation factor activity, non-nucleic acid binding","GO:0007595//lactation;GO:0051491//positive regulation of filopodium assembly;GO:0006513//protein monoubiquitination;GO:0045741//positive regulation of epidermal growth factor-activated receptor activity;GO:0071230//cellular response to amino acid stimulus;GO:0048170//positive regulation of long-term neuronal synaptic plasticity;GO:0043065//positive regulation of apoptotic process;GO:0060999//positive regulation of dendritic spine development;GO:0007288//sperm axoneme assembly;GO:0045746//negative regulation of Notch signaling pathway;GO:0090129//positive regulation of synapse maturation;GO:0008285//negative regulation of cell proliferation","K01931//protein neuralized [EC:2.3.2.27]","XP_017707228.1//PREDICTED: E3 ubiquitin-protein ligase NEURL1 isoform X1 [Rhinopithecus bieti]",4]
[1815,1378,0.53,1.36,1.35954238668714,0.0332759199186992,"*",0.0133237,"DRD4","GO:0016020//membrane;GO:0098794//postsynapse;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane","GO:0004952//dopamine neurotransmitter receptor activity;GO:0015459//potassium channel regulator activity;GO:0042802//identical protein binding;GO:0008144//drug binding;GO:0035240//dopamine binding;GO:0017124//SH3 domain binding;GO:0001591//dopamine neurotransmitter receptor activity, coupled via Gi/Go","GO:0050709//negative regulation of protein secretion;GO:0008344//adult locomotory behavior;GO:0007195//adenylate cyclase-inhibiting dopamine receptor signaling pathway;GO:0042053//regulation of dopamine metabolic process;GO:0007212//dopamine receptor signaling pathway;GO:0050482//arachidonic acid secretion;GO:0007194//negative regulation of adenylate cyclase activity;GO:0042417//dopamine metabolic process;GO:0030818//negative regulation of cAMP biosynthetic process;GO:0006874//cellular calcium ion homeostasis;GO:0034776//response to histamine;GO:0048149//behavioral response to ethanol;GO:0035176//social behavior;GO:0000187//activation of MAPK activity;GO:0048148//behavioral response to cocaine;GO:0060080//inhibitory postsynaptic potential;GO:0048511//rhythmic process;GO:0001662//behavioral fear response;GO:0042752//regulation of circadian rhythm;GO:0001975//response to amphetamine;GO:1901386//negative regulation of voltage-gated calcium channel activity;GO:0032417//positive regulation of sodium:proton antiporter activity;GO:0033674//positive regulation of kinase activity;GO:0051586//positive regulation of dopamine uptake involved in synaptic transmission;GO:0042596//fear response","K04147//dopamine receptor D4","NP_000788.2//D(4) dopamine receptor [Homo sapiens]","3//A2MP1"]
[2894,5849,0.09,0.23,1.3536369546147,0.0924896761569689,"*",0.0427882,"GRID1","GO:0070062//extracellular exosome;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0045211//postsynaptic membrane","GO:0004970//ionotropic glutamate receptor activity;GO:0005234//extracellularly glutamate-gated ion channel activity","GO:0035176//social behavior","K05206//glutamate receptor delta-1 subunit","NP_060021.1//glutamate receptor ionotropic, delta-1 precursor [Homo sapiens]","2//1"]
[348645,1719,0.09,0.23,1.3536369546147,0.434314724232404,"*",0.287794,"C22orf34","NA","NA","NA","K19721//collagen, type V/XI/XXIV/XXVII, alpha","NP_001276851.1//uncharacterized protein C22orf34 [Homo sapiens]","2//1"]
[130,1400,0.09,0.23,1.3536369546147,0.255257059131967,"*",0.1450622,"ADH6","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0004022//alcohol dehydrogenase (NAD) activity;GO:0008270//zinc ion binding;GO:0004024//alcohol dehydrogenase activity, zinc-dependent;GO:0016491//oxidoreductase activity","GO:0006069//ethanol oxidation;GO:0045471//response to ethanol","K13952//alcohol dehydrogenase 6 [EC:1.1.1.1]","NP_001095940.1//alcohol dehydrogenase 6 isoform 1 [Homo sapiens];NP_000663.1//alcohol dehydrogenase 6 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[79934,2181,25.05,63.8,1.34874582056966,{"v":9.02207970222222e-103,"d":"9.02E-103"},"Up",{"v":5.08318E-105,"d":"5.08E-105"},"COQ8B","GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0031966//mitochondrial membrane;GO:0005886//plasma membrane","GO:0005524//ATP binding;GO:0016301//kinase activity","GO:0006744//ubiquinone biosynthetic process;GO:0021692//cerebellar Purkinje cell layer morphogenesis","K08869//aarF domain-containing kinase","NP_001136027.1//atypical kinase COQ8B, mitochondrial isoform b [Homo sapiens];NP_079152.3//atypical kinase COQ8B, mitochondrial isoform a [Homo sapiens]","3//A2MP1;2//1"]
[8510,1246,0.13,0.33,1.34395440121736,0.434437852579853,"*",0.287794,"MMP23B","GO:0031012//extracellular matrix;GO:0005622//intracellular;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005578//proteinaceous extracellular matrix","GO:0008237//metallopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding","GO:0000003//reproduction;GO:0006508//proteolysis","K08001//matrix metalloproteinase-23 (CA-MMP) [EC:3.4.24.-]","XP_011786394.1//PREDICTED: matrix metalloproteinase-23 [Colobus angolensis palliatus]","1//3"]
[55647,1543,0.79,1.99,1.33284387236655,0.0045633830743349,"*",1.460374E-3,"RAB20","GO:0045335//phagocytic vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0005794//Golgi apparatus;GO:0030670//phagocytic vesicle membrane;GO:0005886//plasma membrane;GO:0005769//early endosome","GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0090385//phagosome-lysosome fusion;GO:0030100//regulation of endocytosis;GO:0090383//phagosome acidification;GO:0015031//protein transport","K07911//Ras-related protein Rab-20","NP_060287.1//ras-related protein Rab-20 [Homo sapiens]","2//1"]
[2172,596,0.29,0.73,1.33184356375245,0.434191665659237,"*",0.287794,"FABP6","GO:0016020//membrane;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0008289//lipid binding;GO:0032052//bile acid binding;GO:0005215//transporter activity","GO:0019433//triglyceride catabolic process;GO:0015721//bile acid and bile salt transport;GO:0008285//negative regulation of cell proliferation;GO:0006629//lipid metabolic process","K08755//fatty acid-binding protein 6, ileal (gastrotropin)","XP_008970657.1//PREDICTED: gastrotropin isoform X2 [Pan paniscus];NP_001035532.1//gastrotropin isoform 1 [Homo sapiens]","1//3;2//1"]
[92162,880,0.31,0.78,1.33120590847537,0.203243206040033,"*",0.1086958,"TMEM88","GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0030165//PDZ domain binding","GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0072659//protein localization to plasma membrane;GO:0007275//multicellular organism development;GO:0016055//Wnt signaling pathway;GO:0050821//protein stabilization","K16628//collagen, type VII, alpha","NP_981956.1//transmembrane protein 88 isoform 1 [Homo sapiens];XP_018868687.1//PREDICTED: transmembrane protein 88 isoform X2 [Gorilla gorilla gorilla]","1//3"]
[5366,1954,5.59,14.06,1.33067640622935,{"v":1.92953550280374E-20,"d":"1.93E-20"},"Up",{"v":9.04734e-22,"d":"9.05E-22"},"PMAIP1","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005739//mitochondrion","NA","GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:0071456//cellular response to hypoxia;GO:0042149//cellular response to glucose starvation;GO:0043331//response to dsRNA;GO:0010498//proteasomal protein catabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0043517//positive regulation of DNA damage response, signal transduction by p53 class mediator;GO:0001836//release of cytochrome c from mitochondria;GO:0010907//positive regulation of glucose metabolic process;GO:0051607//defense response to virus;GO:0046902//regulation of mitochondrial membrane permeability;GO:0072593//reactive oxygen species metabolic process;GO:0032461//positive regulation of protein oligomerization;GO:1902043//positive regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process","K10131//phorbol-12-myristate-13-acetate-induced protein 1","XP_004059533.1//PREDICTED: phorbol-12-myristate-13-acetate-induced protein 1 isoform X1 [Gorilla gorilla gorilla]","2//1"]
[6345,4241,0.37,0.93,1.32970544547908,0.000858559013611615,"Up",2.36918E-4,"SRL","GO:0033018//sarcoplasmic reticulum lumen","GO:0005525//GTP binding","NA","K12483//EH domain-containing protein 1;K06236//collagen, type I, alpha","NP_001092284.1//sarcalumenin isoform 1 precursor [Homo sapiens];XP_011715915.1//PREDICTED: sarcalumenin isoform X2 [Macaca nemestrina];XP_017741887.1//PREDICTED: sarcalumenin isoform X1 [Rhinopithecus bieti]","1//3"]
[11074,2065,0.93,2.33,1.32502733354625,0.000283996920728361,"Up",{"v":7.12748e-05,"d":"7.13E-05"},"TRIM31","NA","NA","NA","K12011//tripartite motif-containing protein 31 [EC:2.3.2.27]","XP_009449161.2//PREDICTED: E3 ubiquitin-protein ligase TRIM31 isoform X1 [Pan troglodytes]",4]
[27128,3223,0.1,0.25,1.32192809488736,0.216567877966102,"*",0.1175844,"CYTH4","GO:0005886//plasma membrane","GO:0005086//ARF guanyl-nucleotide exchange factor activity","GO:0032012//regulation of ARF protein signal transduction","K18441//cytohesin","ELV11714.1//Cytohesin-4 [Tupaia chinensis];XP_004279495.1//PREDICTED: cytohesin-4 isoform X1 [Orcinus orca]","4;1//3"]
[273,3300,0.02,0.05,1.32192809488736,0.735911027114887,"*",0.623548,"AMPH","GO:0030672//synaptic vesicle membrane;GO:0008021//synaptic vesicle;GO:0031256//leading edge membrane;GO:0005829//cytosol;GO:0030054//cell junction;GO:0015629//actin cytoskeleton","GO:0005543//phospholipid binding","GO:0006897//endocytosis;GO:0007268//chemical synaptic transmission;GO:0061024//membrane organization","K12562//amphiphysin","NP_647477.1//amphiphysin isoform 2 [Homo sapiens];NP_001626.1//amphiphysin isoform 1 [Homo sapiens]","3//A2MP1;2//1"]
[6340,3516,0.02,0.05,1.32192809488736,0.735584945868104,"*",0.623548,"SCNN1G","GO:0070062//extracellular exosome;GO:0005654//nucleoplasm;GO:0034706//sodium channel complex;GO:0005730//nucleolus;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane","GO:0050699//WW domain binding;GO:0015280//ligand-gated sodium channel activity","GO:0050891//multicellular organismal water homeostasis;GO:0055078//sodium ion homeostasis","K04827//amiloride-sensitive sodium channel subunit gamma","XP_005591514.1//PREDICTED: amiloride-sensitive sodium channel subunit gamma [Macaca fascicularis]","3//A2MP1"]
[343505,1611,0.2,0.5,1.32192809488736,0.216517948772334,"*",0.1175844,"NBPF7","GO:0005737//cytoplasm","NA","NA","K22244//regenerating islet-derived protein 4;K16549//myomegalin","NP_001041445.1//putative neuroblastoma breakpoint family member 7 [Homo sapiens]","2//1"]
[338321,3484,0.02,0.05,1.32192809488736,0.734825212246404,"*",0.623548,"NLRP9","GO:0061702//inflammasome complex","GO:0005524//ATP binding","GO:0032741//positive regulation of interleukin-18 production;GO:0070269//pyroptosis;GO:0051607//defense response to virus;GO:0045087//innate immune response;GO:0006954//inflammatory response","K22265//NACHT, LRR and PYD domains-containing protein 4","NP_789790.2//NACHT, LRR and PYD domains-containing protein 9 [Homo sapiens]","3//A2MP1"]
[201799,3233,0.02,0.05,1.32192809488736,0.734771005606374,"*",0.623548,"TMEM154","GO:0016021//integral component of membrane","NA","NA","NA","NP_689893.1//transmembrane protein 154 precursor [Homo sapiens]","2//1"]
[1427,919,0.18,0.45,1.32192809488736,0.434109665344665,"*",0.287794,"CRYGS","NA","GO:0005212//structural constituent of eye lens","GO:0002009//morphogenesis of an epithelium;GO:0002088//lens development in camera-type eye","K13596//activin receptor type-2B [EC:2.7.11.30];K16810//TBCC domain-containing protein 1","XP_020029684.1//beta-crystallin S isoform X1 [Castor canadensis]","3//A2MP1"]
[51332,11748,0.02,0.05,1.32192809488736,0.255228944024672,"*",0.1450622,"SPTBN5","NA","NA","NA","K06115//spectrin beta","EAW92523.1//spectrin, beta, non-erythrocytic 5 [Homo sapiens]","3//A2MP1"]
[84281,3978,0.04,0.1,1.32192809488736,0.434027695996979,"*",0.287794,"C2orf88","GO:0005886//plasma membrane","GO:0034237//protein kinase A regulatory subunit binding","NA","K17580//cancer susceptibility candidate protein 1","NP_115697.2//small membrane A-kinase anchor protein [Homo sapiens]","1//3;2//1"]
[79949,3263,0.02,0.05,1.32192809488736,0.733526456440091,"*",0.623548,"PLEKHS1","NA","NA","NA","K10955//mucin-2;K04397//caspase 7 [EC:3.4.22.60]","XP_011538473.1//PREDICTED: pleckstrin homology domain-containing family S member 1 isoform X1 [Homo sapiens];NP_872407.1//pleckstrin homology domain-containing family S member 1 isoform 1 [Homo sapiens];XP_005270220.1//PREDICTED: pleckstrin homology domain-containing family S member 1 isoform X4 [Homo sapiens]","4;1//3"]
[644090,2211,0.08,0.2,1.32192809488736,0.4339048,"*",0.287794,"LOC644090","NA","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K02927//large subunit ribosomal protein L40e;K17985//activating molecule in BECN1-regulated autophagy protein 1;K01064//wingless-type MMTV integration site family, member 9","EAW53985.1//hCG2038711, partial [Homo sapiens]","1//3"]
[91608,3213,0.1,0.25,1.32192809488736,0.216468042595367,"*",0.1175844,"RASL10B","GO:0016020//membrane","GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0007165//signal transduction","K07851//Ras-like protein family member 10B","XP_009430660.1//PREDICTED: ras-like protein family member 10B isoform X1 [Pan troglodytes]","3//A2MP1"]
[10221,3190,14.62,36.44,1.31757964784961,{"v":1.67061025147059e-72,"d":"1.67E-72"},"Up",{"v":1.42233E-74,"d":"1.42E-74"},"TRIB1","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0031434//mitogen-activated protein kinase kinase binding;GO:0005524//ATP binding;GO:0004860//protein kinase inhibitor activity;GO:0004672//protein kinase activity;GO:0031625//ubiquitin protein ligase binding;GO:0055106//ubiquitin-protein transferase regulator activity;GO:0008134//transcription factor binding","GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0043433//negative regulation of DNA binding transcription factor activity;GO:0031665//negative regulation of lipopolysaccharide-mediated signaling pathway;GO:0032496//response to lipopolysaccharide;GO:0043405//regulation of MAP kinase activity;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0007254//JNK cascade;GO:0006469//negative regulation of protein kinase activity;GO:0014912//negative regulation of smooth muscle cell migration;GO:0045645//positive regulation of eosinophil differentiation;GO:0045651//positive regulation of macrophage differentiation;GO:0045659//negative regulation of neutrophil differentiation","K08814//tribbles homolog 1/2","NP_079471.1//tribbles homolog 1 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[60680,3754,0.21,0.52,1.30812229536233,0.110445014193548,"*",0.0525122,"CELF5","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0036002//pre-mRNA binding","GO:0006397//mRNA processing;GO:0000381//regulation of alternative mRNA splicing, via spliceosome","K13207//CUG-BP- and ETR3-like factor","NP_068757.2//CUGBP Elav-like family member 5 isoform 1 [Homo sapiens];BAD92304.1//bruno-like 5, RNA binding protein variant, partial [Homo sapiens]","1//3;3//A2MP1"]
[2266,1753,0.28,0.69,1.30116953472056,0.109350094911679,"*",0.05193,"FGG","GO:0070062//extracellular exosome;GO:0005788//endoplasmic reticulum lumen;GO:0005577//fibrinogen complex;GO:0005615//extracellular space;GO:0072562//blood microparticle;GO:0009897//external side of plasma membrane;GO:0031093//platelet alpha granule lumen;GO:0009986//cell surface;GO:0031091//platelet alpha granule;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0046872//metal ion binding;GO:0050839//cell adhesion molecule binding;GO:0030674//protein binding, bridging;GO:0005198//structural molecule activity;GO:0005102//receptor binding;GO:0042803//protein homodimerization activity","GO:0043687//post-translational protein modification;GO:0007596//blood coagulation;GO:0045921//positive regulation of exocytosis;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:0036345//platelet maturation;GO:0044267//cellular protein metabolic process;GO:0002576//platelet degranulation;GO:0045907//positive regulation of vasoconstriction;GO:0071347//cellular response to interleukin-1;GO:0071354//cellular response to interleukin-6;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0072378//blood coagulation, fibrin clot formation;GO:0090277//positive regulation of peptide hormone secretion;GO:0090331//negative regulation of platelet aggregation;GO:0034116//positive regulation of heterotypic cell-cell adhesion;GO:0042730//fibrinolysis;GO:0002224//toll-like receptor signaling pathway;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:0031639//plasminogen activation;GO:0051258//protein polymerization;GO:0050714//positive regulation of protein secretion;GO:0007160//cell-matrix adhesion;GO:0051592//response to calcium ion;GO:0009306//protein secretion;GO:0030198//extracellular matrix organization;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070527//platelet aggregation;GO:0043623//cellular protein complex assembly","K03905//fibrinogen gamma chain","AAB59531.1//fibrinogen gamma chain [Homo sapiens];NP_068656.2//fibrinogen gamma chain isoform gamma-B precursor [Homo sapiens]","2//1;5"]
[114571,2327,0.11,0.27,1.29545588352617,0.36458648541329,"*",0.225316,"SLC22A9","GO:0016323//basolateral plasma membrane;GO:0005887//integral component of plasma membrane","GO:0015143//urate transmembrane transporter activity;GO:0015301//anion:anion antiporter activity;GO:0005452//inorganic anion exchanger activity;GO:0015347//sodium-independent organic anion transmembrane transporter activity;GO:0015636//short-chain fatty acid transmembrane transporter activity","GO:0043252//sodium-independent organic anion transport;GO:0009914//hormone transport;GO:0015747//urate transport;GO:0015913//short-chain fatty acid import","K08206//MFS transporter, OCT family, solute carrier family 22 (organic anion/cation transporter), member 9/10/19/24/25","NP_543142.2//solute carrier family 22 member 9 [Homo sapiens]","2//1"]
[100130958,734,1.5,3.68,1.29474326556113,0.0125019345877378,"*",0.00444228,"SYCE1L","GO:0045111//intermediate filament cytoskeleton;GO:0000795//synaptonemal complex","NA","GO:0007130//synaptonemal complex assembly","K19534//synaptonemal complex central element protein 1","NP_001123451.1//synaptonemal complex central element protein 1-like isoform 1 [Homo sapiens];NP_001335853.1//synaptonemal complex central element protein 1-like isoform 2 [Homo sapiens]","1//3;2//1"]
[148932,2804,1.99,4.88,1.29411271701924,{"v":2.63525251073986e-10,"d":"2.64E-10"},"Up",{"v":2.76492E-11,"d":"2.76E-11"},"MOB3C","NA","NA","NA","K06685//MOB kinase activator 1","XP_016817891.1//PREDICTED: MOB kinase activator 3C isoform X1 [Pan troglodytes];NP_660322.2//MOB kinase activator 3C isoform 1 [Homo sapiens]","4;2//1"]
[149483,2240,0.29,0.71,1.29176612437711,0.0554111514285714,"*",0.0237962,"CCDC17","NA","NA","NA","K06236//collagen, type I, alpha","XP_001158794.3//PREDICTED: coiled-coil domain-containing protein 17 [Pan troglodytes]","1//3;2//1"]
[9214,2773,1.21,2.96,1.29059012835436,{"v":1.64387406432749E-6,"d":"1.64E-06"},"Up",{"v":2.8156e-07,"d":"2.82E-07"},"FCMR","GO:0016021//integral component of membrane;GO:0005576//extracellular region","NA","GO:0002376//immune system process;GO:0043066//negative regulation of apoptotic process;GO:0006968//cellular defense response","K13073//polymeric immunoglobulin receptor;K16851//high affinity immunoglobulin alpha and immunoglobulin mu Fc receptor","NP_001135945.1//fas apoptotic inhibitory molecule 3 isoform b [Homo sapiens];NP_001180267.1//fas apoptotic inhibitory molecule 3 isoform c precursor [Homo sapiens];NP_005440.1//fas apoptotic inhibitory molecule 3 isoform a precursor [Homo sapiens]","1//3;4"]
[90317,4386,0.07,0.17,1.28010791919274,0.303592796718517,"*",0.178385,"ZNF616","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","NP_848618.2//zinc finger protein 616 [Homo sapiens]",4]
[4016,2371,0.07,0.17,1.28010791919274,0.434396802041009,"*",0.287794,"LOXL1","GO:0031012//extracellular matrix;GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0001669//acrosomal vesicle;GO:0005604//basement membrane","GO:0016641//oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor;GO:0005507//copper ion binding","GO:0018277//protein deamination;GO:0030198//extracellular matrix organization;GO:0032496//response to lipopolysaccharide;GO:0055114//oxidation-reduction process;GO:0035904//aorta development","K14678//lysyl oxidase-like protein 1 [EC:1.4.3.-]","NP_005567.2//lysyl oxidase homolog 1 preproprotein [Homo sapiens]","3//A2MP1"]
[10235,2239,0.07,0.17,1.28010791919274,0.434355759259259,"*",0.287794,"RASGRP2","NA","NA","NA","K12361//RAS guanyl-releasing protein 2","XP_015289997.1//PREDICTED: RAS guanyl-releasing protein 2 isoform X1 [Macaca fascicularis];XP_005273764.3//PREDICTED: RAS guanyl-releasing protein 2 isoform X4 [Homo sapiens];AAF07219.1//guanine exchange factor MCG7 isoform 1 [Homo sapiens];AAI10307.1//RASGRP2 protein, partial [Homo sapiens]","1//3"]
[5837,3369,0.07,0.17,1.28010791919274,0.364549557783855,"*",0.225316,"PYGM","NA","GO:0102250//linear malto-oligosaccharide phosphorylase activity;GO:0030170//pyridoxal phosphate binding;GO:0008184//glycogen phosphorylase activity;GO:0102499//SHG alpha-glucan phosphorylase activity","GO:0005975//carbohydrate metabolic process","K00688//glycogen phosphorylase [EC:2.4.1.1]","XP_007070426.1//PREDICTED: glycogen phosphorylase, muscle form isoform X3 [Chelonia mydas];XP_019501148.1//PREDICTED: glycogen phosphorylase, muscle form [Hipposideros armiger]","1//3;3//A2MP1"]
[221472,3045,0.07,0.17,1.28010791919274,0.303769768996702,"*",0.1787362,"FGD2","GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0032587//ruffle membrane;GO:0030027//lamellipodium;GO:0005737//cytoplasm;GO:0001726//ruffle;GO:0031901//early endosome membrane;GO:0005829//cytosol;GO:0005794//Golgi apparatus","GO:0031267//small GTPase binding;GO:1901981//phosphatidylinositol phosphate binding;GO:0046872//metal ion binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005089//Rho guanyl-nucleotide exchange factor activity","GO:0046847//filopodium assembly;GO:0030036//actin cytoskeleton organization;GO:0008360//regulation of cell shape;GO:0043507//positive regulation of JUN kinase activity;GO:0043065//positive regulation of apoptotic process;GO:0043087//regulation of GTPase activity;GO:0007010//cytoskeleton organization;GO:0035023//regulation of Rho protein signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction","K05721//FYVE, RhoGEF and PH domain containing 2","NP_775829.2//FYVE, RhoGEF and PH domain-containing protein 2 [Homo sapiens]","3//A2MP1"]
[4791,3212,18.93,45.84,1.2759326330532,{"v":1.49139587041667E-99,"d":"1.49E-99"},"Up",{"v":8.96294e-102,"d":"8.96E-102"},"NFKB2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0033257//Bcl3/NF-kappaB2 complex;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003713//transcription coactivator activity;GO:0003682//chromatin binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0038061//NIK/NF-kappaB signaling;GO:0032481//positive regulation of type I interferon production;GO:0006355//regulation of transcription, DNA-templated;GO:0034097//response to cytokine;GO:0032496//response to lipopolysaccharide;GO:0002268//follicular dendritic cell differentiation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0048536//spleen development;GO:0045087//innate immune response;GO:0007165//signal transduction;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0048511//rhythmic process;GO:0007568//aging;GO:0006954//inflammatory response;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0002467//germinal center formation;GO:0030198//extracellular matrix organization;GO:0045944//positive regulation of transcription from RNA polymerase II promoter","K04469//nuclear factor of kappa light polypeptide gene enhancer in B-cells 2","NP_002493.3//nuclear factor NF-kappa-B p100 subunit isoform b [Homo sapiens];XP_016871767.1//PREDICTED: nuclear factor NF-kappa-B p100 subunit isoform X1 [Homo sapiens];NP_001309864.1//nuclear factor NF-kappa-B p100 subunit isoform c [Homo sapiens];XP_017799765.1//nuclear factor NF-kappa-B p100 subunit isoform X2 [Papio anubis];NP_001070962.1//nuclear factor NF-kappa-B p100 subunit isoform a [Homo sapiens]","1//3;3//A2MP1;2//1;5"]
[3428,2750,2.15,5.16,1.26303440583379,{"v":2.79222101070155e-10,"d":"2.79E-10"},"Up",{"v":2.9401e-11,"d":"2.94E-11"},"IFI16","GO:0016020//membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0016607//nuclear speck","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003723//RNA binding;GO:0042802//identical protein binding;GO:0008134//transcription factor binding;GO:0003690//double-stranded DNA binding;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0001047//core promoter binding","GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:0032481//positive regulation of type I interferon production;GO:0002218//activation of innate immune response;GO:0030099//myeloid cell differentiation;GO:0097202//activation of cysteine-type endopeptidase activity;GO:0001819//positive regulation of cytokine production;GO:0042149//cellular response to glucose starvation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0045071//negative regulation of viral genome replication;GO:0006914//autophagy;GO:0010506//regulation of autophagy;GO:0045087//innate immune response;GO:0030097//hemopoiesis;GO:0032731//positive regulation of interleukin-1 beta production;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045824//negative regulation of innate immune response;GO:0040029//regulation of gene expression, epigenetic;GO:0051607//defense response to virus;GO:0006351//transcription, DNA-templated;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0006954//inflammatory response;GO:2000117//negative regulation of cysteine-type endopeptidase activity;GO:0043392//negative regulation of DNA binding;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0071479//cellular response to ionizing radiation;GO:0030224//monocyte differentiation","K20914//gamma-interferon-inducible protein 16","BAD92226.1//Interferon, gamma-inducible protein 16 variant, partial [Homo sapiens];NP_001193496.1//gamma-interferon-inducible protein 16 isoform 1 [Homo sapiens]","1//3;2//1"]
[4320,2306,0.1,0.24,1.26303440583379,0.364660363120567,"*",0.225316,"MMP11","GO:0031012//extracellular matrix;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix;GO:0005796//Golgi lumen","GO:0004252//serine-type endopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding","GO:0022617//extracellular matrix disassembly;GO:0071711//basement membrane organization;GO:0006508//proteolysis;GO:0007275//multicellular organism development;GO:0030199//collagen fibril organization;GO:0045599//negative regulation of fat cell differentiation;GO:0030574//collagen catabolic process","K07993//matrix metalloproteinase-11 (stromelysin 3) [EC:3.4.24.-]","NP_005931.2//stromelysin-3 preproprotein [Homo sapiens]",4]
[6376,3341,0.05,0.12,1.26303440583379,0.434150661629993,"*",0.287794,"CX3CL1","GO:0005615//extracellular space;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0031737//CX3C chemokine receptor binding;GO:0005178//integrin binding;GO:0005102//receptor binding;GO:0008009//chemokine activity;GO:0048020//CCR chemokine receptor binding","GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0051041//positive regulation of calcium-independent cell-cell adhesion;GO:0050902//leukocyte adhesive activation;GO:0060055//angiogenesis involved in wound healing;GO:0050729//positive regulation of inflammatory response;GO:0043547//positive regulation of GTPase activity;GO:0071356//cellular response to tumor necrosis factor;GO:0033622//integrin activation;GO:0002523//leukocyte migration involved in inflammatory response;GO:0071346//cellular response to interferon-gamma;GO:0071347//cellular response to interleukin-1;GO:0048246//macrophage chemotaxis;GO:0045766//positive regulation of angiogenesis;GO:0002548//monocyte chemotaxis;GO:0006935//chemotaxis;GO:0032914//positive regulation of transforming growth factor beta1 production;GO:0007186//G-protein coupled receptor signaling pathway;GO:0048247//lymphocyte chemotaxis;GO:0030593//neutrophil chemotaxis;GO:0070098//chemokine-mediated signaling pathway;GO:0030595//leukocyte chemotaxis;GO:0030336//negative regulation of cell migration;GO:0006954//inflammatory response;GO:0007155//cell adhesion;GO:0006952//defense response;GO:0006955//immune response;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0019221//cytokine-mediated signaling pathway","K05508//C-X3-C motif chemokine 1","NP_002987.1//fractalkine isoform 1 precursor [Homo sapiens]","2//1;5"]
[64109,1503,0.2,0.48,1.26303440583379,0.303560454884415,"*",0.178385,"CRLF2","GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane","NA","NA","K05078//thymic stromal-derived lymphopoietin receptor","NP_071431.2//cytokine receptor-like factor 2 isoform 1 precursor [Homo sapiens]","3//A2MP1;2//1"]
[9605,2767,7.58,18.15,1.25969979471202,{"v":3.90153850899183e-34,"d":"3.90E-34"},"Up",{"v":8.96372e-36,"d":"8.96E-36"},"VPS9D1","NA","GO:0005215//transporter activity;GO:0005096//GTPase activator activity","GO:0015986//ATP synthesis coupled proton transport","K16628//collagen, type VII, alpha;K06236//collagen, type I, alpha;K21952//CASK-interacting protein","NP_004904.2//VPS9 domain-containing protein 1 [Homo sapiens]","2//1"]
[7454,1844,0.13,0.31,1.25375659224578,0.364438819765087,"*",0.225316,"WAS","GO:0012506//vesicle membrane;GO:0070062//extracellular exosome;GO:0005884//actin filament;GO:0005829//cytosol;GO:0005911//cell-cell junction;GO:0005622//intracellular;GO:0015629//actin cytoskeleton","GO:0031267//small GTPase binding;GO:0048365//Rac GTPase binding;GO:0042802//identical protein binding;GO:0043274//phospholipase binding;GO:0019901//protein kinase binding;GO:0030695//GTPase regulator activity;GO:0003779//actin binding;GO:0017124//SH3 domain binding","GO:0030048//actin filament-based movement;GO:0007596//blood coagulation;GO:0010591//regulation of lamellipodium assembly;GO:0007015//actin filament organization;GO:0051497//negative regulation of stress fiber assembly;GO:0008154//actin polymerization or depolymerization;GO:2000601//positive regulation of Arp2/3 complex-mediated actin nucleation;GO:2000146//negative regulation of cell motility;GO:0030041//actin filament polymerization;GO:0051492//regulation of stress fiber assembly;GO:0032488//Cdc42 protein signal transduction;GO:0016197//endosomal transport;GO:0042110//T cell activation;GO:0008064//regulation of actin polymerization or depolymerization;GO:0050852//T cell receptor signaling pathway;GO:0002625//regulation of T cell antigen processing and presentation;GO:0008544//epidermis development;GO:0006952//defense response;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0006955//immune response;GO:0006461//protein complex assembly","K05747//Wiskott-Aldrich syndrome protein","AAH02961.1//WAS protein, partial [Homo sapiens]","2//1"]
[55061,2672,0.13,0.31,1.25375659224578,0.628460563962983,"*",0.505908,"SUSD4","GO:0016021//integral component of membrane;GO:0005576//extracellular region","NA","GO:0006958//complement activation, classical pathway;GO:0030449//regulation of complement activation;GO:0045959//negative regulation of complement activation, classical pathway;GO:0045957//negative regulation of complement activation, alternative pathway;GO:0045087//innate immune response","K17495//CUB and sushi domain-containing protein","NP_060452.3//sushi domain-containing protein 4 isoform a precursor [Homo sapiens];NP_001032252.1//sushi domain-containing protein 4 isoform b precursor [Homo sapiens]","3//A2MP1;2//1"]
[59344,3251,0.67,1.59,1.24679376482658,0.000665475876594758,"Up",0.000179596,"ALOXE3","NA","NA","NA","K18684//hydroperoxy icosatetraenoate dehydratase/isomerase [EC:4.2.1.152 5.4.4.7]","XP_016787958.1//PREDICTED: hydroperoxide isomerase ALOXE3 [Pan troglodytes]","1//3;2//1"]
[2635,3086,0.68,1.61,1.24345403686428,0.000244132057417722,"Up",{"v":6.03682e-05,"d":"6.04E-05"},"GBP3","GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm;GO:0000139//Golgi membrane","GO:0019955//cytokine binding;GO:0019003//GDP binding;GO:0042803//protein homodimerization activity;GO:0003924//GTPase activity;GO:0003779//actin binding;GO:0051879//Hsp90 protein binding;GO:0005525//GTP binding;GO:0019899//enzyme binding;GO:0030507//spectrin binding","GO:0050860//negative regulation of T cell receptor signaling pathway;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:1903077//negative regulation of protein localization to plasma membrane;GO:1900025//negative regulation of substrate adhesion-dependent cell spreading;GO:0050848//regulation of calcium-mediated signaling;GO:0051607//defense response to virus;GO:0051260//protein homooligomerization;GO:1900041//negative regulation of interleukin-2 secretion","K20899//guanylate-binding protein 1/3/4/7","XP_021522106.1//guanylate-binding protein 3 isoform X2 [Aotus nancymaae];NP_001306110.1//guanylate-binding protein 3 isoform 4 [Homo sapiens];XP_011811446.1//PREDICTED: guanylate-binding protein 3 isoform X1 [Colobus angolensis palliatus]","1//3;2//1"]
[375704,1093,1.65,3.9,1.2410080995038,0.0015049331232166,"*",0.000435822,"ENHO","NA","NA","NA","NA","XP_016816258.1//PREDICTED: adropin isoform X1 [Pan troglodytes]","2//1"]
[84866,1546,0.14,0.33,1.23703919730085,0.495892554527309,"*",0.342164,"TMEM25","GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K11447//histone demethylase [EC:1.14.11.-];K01064//wingless-type MMTV integration site family, member 9","XP_016775328.1//PREDICTED: transmembrane protein 25 isoform X7 [Pan troglodytes];XP_012351331.1//PREDICTED: transmembrane protein 25 isoform X5 [Nomascus leucogenys];XP_016775329.1//PREDICTED: transmembrane protein 25 isoform X10 [Pan troglodytes];XP_014640594.1//PREDICTED: transmembrane protein 25 isoform X8 [Ceratotherium simum simum];XP_008971702.1//PREDICTED: transmembrane protein 25 isoform X5 [Pan paniscus];XP_009422324.1//PREDICTED: transmembrane protein 25 isoform X5 [Pan troglodytes];NP_001305686.1//transmembrane protein 25 isoform 7 precursor [Homo sapiens]","1//3;3//A2MP1"]
[124402,1428,67.8,159.54,1.23456100455512,{"v":2.08771516135593e-146,"d":"2.09E-146"},"Up",{"v":7.71098e-149,"d":"7.71E-149"},"UBALD1","NA","NA","NA","K16628//collagen, type VII, alpha;K03129//transcription initiation factor TFIID subunit 4;K20630//chimaerin;K15297//regulating synaptic membrane exocytosis protein 2","NP_660296.1//UBA-like domain-containing protein 1 isoform 1 [Homo sapiens];NP_001317396.1//UBA-like domain-containing protein 1 isoform 2 [Homo sapiens]","1//3;2//1"]
[100529261,2894,4.12,9.65,1.22788460497222,{"v":1.2025166991755E-18,"d":"1.20E-18"},"Up",{"v":6.39124e-20,"d":"6.39E-20"},"CHURC1-FNTB","GO:0005875//microtubule associated complex;GO:0005965//protein farnesyltransferase complex;GO:0005829//cytosol","GO:0019840//isoprenoid binding;GO:0004311//farnesyltranstransferase activity;GO:0008144//drug binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0004660//protein farnesyltransferase activity;GO:0042277//peptide binding","GO:0014070//response to organic cyclic compound;GO:0042127//regulation of cell proliferation;GO:0042060//wound healing;GO:0034097//response to cytokine;GO:0048146//positive regulation of fibroblast proliferation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0018343//protein farnesylation;GO:0051770//positive regulation of nitric-oxide synthase biosynthetic process;GO:0007275//multicellular organism development;GO:0010035//response to inorganic substance;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0008285//negative regulation of cell proliferation;GO:0045787//positive regulation of cell cycle","K05954//protein farnesyltransferase subunit beta [EC:2.5.1.58]","NP_001189487.1//CHURC1-FNTB protein isoform 2 [Homo sapiens];NP_001189488.1//CHURC1-FNTB protein isoform 1 [Homo sapiens]","1//3"]
[2212,2426,0.03,0.07,1.22239242133645,0.73601978511786,"*",0.623548,"FCGR2A","GO:0070062//extracellular exosome;GO:0030667//secretory granule membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0019864//IgG binding","GO:0043312//neutrophil degranulation;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis","K06472//low affinity immunoglobulin gamma Fc receptor II-a","NP_067674.2//low affinity immunoglobulin gamma Fc region receptor II-a isoform 2 precursor [Homo sapiens];NP_001129691.1//low affinity immunoglobulin gamma Fc region receptor II-a isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[7122,2332,0.09,0.21,1.22239242133645,0.303996173211244,"*",0.1787362,"CLDN5","GO:0070062//extracellular exosome;GO:0016327//apicolateral plasma membrane;GO:0030054//cell junction;GO:0043220//Schmidt-Lanterman incisure;GO:0033270//paranode region of axon;GO:0005911//cell-cell junction;GO:0005923//bicellular tight junction;GO:0016021//integral component of membrane;GO:0016328//lateral plasma membrane;GO:0005886//plasma membrane","GO:0042802//identical protein binding;GO:0005198//structural molecule activity","GO:0042552//myelination;GO:0007043//cell-cell junction assembly;GO:2000810//regulation of bicellular tight junction assembly;GO:0007612//learning;GO:0003151//outflow tract morphogenesis;GO:0045471//response to ethanol;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;GO:0060325//face morphogenesis;GO:0060021//palate development;GO:1903142//positive regulation of establishment of endothelial barrier","K06087//claudin","NP_003268.2//claudin-5 [Homo sapiens]","1//3;3//A2MP1"]
[3239,2341,0.03,0.07,1.22239242133645,0.734391782938878,"*",0.623548,"HOXD13","GO:0005634//nucleus","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0001158//enhancer sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0060602//branch elongation of an epithelium;GO:0009952//anterior/posterior pattern specification;GO:0006355//regulation of transcription, DNA-templated;GO:0042127//regulation of cell proliferation;GO:0060527//prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0060687//regulation of branching involved in prostate gland morphogenesis;GO:0042733//embryonic digit morphogenesis;GO:0048619//embryonic hindgut morphogenesis;GO:0030539//male genitalia development;GO:0033574//response to testosterone;GO:0060571//morphogenesis of an epithelial fold;GO:0007275//multicellular organism development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0001501//skeletal system development","K09298//homeobox protein HoxA/C/D13","NP_000514.2//homeobox protein Hox-D13 [Homo sapiens]","3//A2MP1"]
[101060200,2303,0.21,0.49,1.22239242133645,0.152442875651746,"*",0.0776052,"ZNF891","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_005339407.2//uncharacterized protein LOC101958065 [Ictidomys tridecemlineatus]","1//3"]
[83875,2795,0.09,0.21,1.22239242133645,0.364328149002936,"*",0.225316,"BCO2","GO:0005759//mitochondrial matrix;GO:0005622//intracellular;GO:0005739//mitochondrion","GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0046872//metal ion binding;GO:0102076//beta,beta-carotene-9',10'-cleaving oxygenase activity","GO:0016116//carotenoid metabolic process;GO:0016122//xanthophyll metabolic process;GO:0042574//retinal metabolic process;GO:0016119//carotene metabolic process;GO:0055114//oxidation-reduction process;GO:0016121//carotene catabolic process;GO:0042573//retinoic acid metabolic process;GO:0001523//retinoid metabolic process;GO:2000377//regulation of reactive oxygen species metabolic process;GO:0051881//regulation of mitochondrial membrane potential","K10252//beta,beta-carotene 9',10'-dioxygenase [EC:1.13.11.71]","NP_001243327.1//beta,beta-carotene 9',10'-oxygenase isoform d [Homo sapiens];XP_014971178.1//PREDICTED: beta,beta-carotene 9',10'-oxygenase isoform X1 [Macaca mulatta];NP_001032367.2//beta,beta-carotene 9',10'-oxygenase isoform b [Homo sapiens];NP_114144.4//beta,beta-carotene 9',10'-oxygenase isoform a [Homo sapiens]","1//3;2//1;5"]
[55584,2292,0.03,0.07,1.22239242133645,0.733418433988661,"*",0.623548,"CHRNA9","GO:0005887//integral component of plasma membrane;GO:0005892//acetylcholine-gated channel complex;GO:0030054//cell junction;GO:0005886//plasma membrane;GO:0045211//postsynaptic membrane","GO:0015276//ligand-gated ion channel activity;GO:0005262//calcium channel activity;GO:0022848//acetylcholine-gated cation-selective channel activity","GO:0042472//inner ear morphogenesis;GO:0050910//detection of mechanical stimulus involved in sensory perception of sound;GO:0007204//positive regulation of cytosolic calcium ion concentration","K04810//nicotinic acetylcholine receptor alpha-9","NP_060051.2//neuronal acetylcholine receptor subunit alpha-9 precursor [Homo sapiens]","3//A2MP1"]
[7092,7284,0.03,0.07,1.22239242133645,1.01432816213808,"*",0.997882,"TLL1","NA","GO:0004222//metalloendopeptidase activity;GO:0005509//calcium ion binding;GO:0008270//zinc ion binding","NA","K09608//tolloid-like protein 1 [EC:3.4.24.-]","XP_004392728.1//PREDICTED: tolloid-like protein 1 [Odobenus rosmarus divergens];XP_011714130.1//PREDICTED: tolloid-like protein 1 isoform X1 [Macaca nemestrina]","1//3;4"]
[440738,1192,3.98,9.28,1.22135637458392,{"v":1.33637909100257E-7,"d":"1.34E-07"},"Up",{"v":1.952616E-8,"d":"1.95E-08"},"MAP1LC3C","GO:0005829//cytosol;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0005776//autophagosome;GO:0000421//autophagosome membrane","GO:0031625//ubiquitin protein ligase binding","GO:0097352//autophagosome maturation;GO:0006995//cellular response to nitrogen starvation;GO:0009267//cellular response to starvation;GO:0000045//autophagosome assembly;GO:0035973//aggrephagy;GO:0000422//autophagy of mitochondrion","K10435//microtubule-associated protein 1 light chain","XP_011811086.1//PREDICTED: microtubule-associated proteins 1A/1B light chain 3C [Colobus angolensis palliatus]","2//1"]
[5371,3348,7.36,17.16,1.22127188144253,{"v":2.48497512307692E-34,"d":"2.48E-34"},"Up",{"v":5.66252E-36,"d":"5.66E-36"},"PML","GO:0016605//PML body;GO:0005654//nucleoplasm;GO:0000784//nuclear chromosome, telomeric region;GO:0016363//nuclear matrix;GO:0005737//cytoplasm;GO:0031901//early endosome membrane;GO:0042406//extrinsic component of endoplasmic reticulum membrane;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0000792//heterochromatin","GO:0003677//DNA binding;GO:0031625//ubiquitin protein ligase binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0050897//cobalt ion binding;GO:0008270//zinc ion binding;GO:0046332//SMAD binding;GO:0032183//SUMO binding","GO:0097191//extrinsic apoptotic signaling pathway;GO:0050713//negative regulation of interleukin-1 beta secretion;GO:0060444//branching involved in mammary gland duct morphogenesis;GO:0010332//response to gamma radiation;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:0045087//innate immune response;GO:0008285//negative regulation of cell proliferation;GO:0051457//maintenance of protein location in nucleus;GO:0045892//negative regulation of transcription, DNA-templated;GO:0043153//entrainment of circadian clock by photoperiod;GO:0007182//common-partner SMAD protein phosphorylation;GO:0048146//positive regulation of fibroblast proliferation;GO:0045345//positive regulation of MHC class I biosynthetic process;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0001666//response to hypoxia;GO:0006915//apoptotic process;GO:0010761//fibroblast migration;GO:1990830//cellular response to leukemia inhibitory factor;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:2000059//negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006461//protein complex assembly;GO:0030099//myeloid cell differentiation;GO:0007184//SMAD protein import into nucleus;GO:0007050//cell cycle arrest;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0001932//regulation of protein phosphorylation;GO:0090398//cellular senescence;GO:2000779//regulation of double-strand break repair;GO:0032922//circadian regulation of gene expression;GO:0071353//cellular response to interleukin-4;GO:0030155//regulation of cell adhesion;GO:0045165//cell fate commitment;GO:0030308//negative regulation of cell growth;GO:0030578//PML body organization;GO:0009411//response to UV;GO:0008631//intrinsic apoptotic signaling pathway in response to oxidative stress;GO:0016525//negative regulation of angiogenesis;GO:0048384//retinoic acid receptor signaling pathway;GO:1902187//negative regulation of viral release from host cell;GO:0032206//positive regulation of telomere maintenance;GO:0010522//regulation of calcium ion transport into cytosol;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0032469//endoplasmic reticulum calcium ion homeostasis;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest","K10054//probable transcription factor PML","NP_150253.2//protein PML isoform 11 [Homo sapiens];AAG50184.1//tripartite motif protein TRIM19 epsilon [Homo sapiens];NP_150243.2//protein PML isoform 2 [Homo sapiens];NP_002666.1//protein PML isoform 6 [Homo sapiens];NP_150242.1//protein PML isoform 9 [Homo sapiens];BAD92648.1//promyelocytic leukemia protein isoform 1 variant, partial [Homo sapiens];NP_150241.2//protein PML isoform 1 [Homo sapiens]","3//A2MP1;2//1"]
[377677,3855,0.71,1.65,1.21657509474113,{"v":5.92738472583826E-5,"d":"5.93E-05"},"Up",{"v":1.316908e-05,"d":"1.32E-05"},"CA13","GO:0043231//intracellular membrane-bounded organelle;GO:0005829//cytosol;GO:0043209//myelin sheath","GO:0008270//zinc ion binding;GO:0004089//carbonate dehydratase activity","GO:0006730//one-carbon metabolic process","K01672//carbonic anhydrase [EC:4.2.1.1]","XP_017705363.1//PREDICTED: carbonic anhydrase 13 [Rhinopithecus bieti]","2//1"]
[9048,1951,0.25,0.58,1.21412480535285,0.21140751280389,"*",0.1143194,"ARTN","GO:0005615//extracellular space;GO:0005622//intracellular;GO:0005576//extracellular region","GO:0008083//growth factor activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005102//receptor binding","GO:0000165//MAPK cascade;GO:0007165//signal transduction;GO:0050930//induction of positive chemotaxis;GO:0007405//neuroblast proliferation;GO:0061146//Peyer's patch morphogenesis;GO:0007422//peripheral nervous system development;GO:0007411//axon guidance;GO:0097021//lymphocyte migration into lymphoid organs","K16628//collagen, type VII, alpha;K05452//glial cell derived neurotrophic factor","NP_476431.2//artemin isoform 3 [Homo sapiens];NP_476432.2//artemin isoform 1 preproprotein [Homo sapiens]","1//3;2//1"]
[146378,815,0.16,0.37,1.20945336562895,0.530371421211583,"*",0.37379,"C16orf92","GO:0016021//integral component of membrane","NA","NA","NA","XP_001147584.2//PREDICTED: uncharacterized protein C16orf92 homolog [Pan troglodytes];NP_001103130.1//uncharacterized protein C16orf92 isoform 2 [Homo sapiens];NP_001340308.1//uncharacterized protein C16orf92 isoform 3 precursor [Homo sapiens]","1//3"]
[4616,1393,19.87,45.91,1.2082165594627,{"v":6.88591113594771e-40,"d":"6.89E-40"},"Up",{"v":1.319074e-41,"d":"1.32E-41"},"GADD45B","GO:0005634//nucleus;GO:0005737//cytoplasm","NA","GO:0046330//positive regulation of JNK cascade;GO:1900745//positive regulation of p38MAPK cascade;GO:0043065//positive regulation of apoptotic process;GO:0006469//negative regulation of protein kinase activity;GO:0000185//activation of MAPKKK activity;GO:0006950//response to stress;GO:0051726//regulation of cell cycle;GO:0000186//activation of MAPKK activity","K04402//growth arrest and DNA-damage-inducible protein","EAW69377.1//growth arrest and DNA-damage-inducible, beta, isoform CRA_b, partial [Homo sapiens]","3//A2MP1"]
[135152,1925,0.29,0.67,1.2081081953302,0.128881117836183,"*",0.0632384,"B3GAT2","NA","NA","NA","K10157//galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2 [EC:2.4.1.135]","XP_009240275.1//PREDICTED: LOW QUALITY PROTEIN: galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2 [Pongo abelii]","2//1"]
[4170,3939,39.91,92.2,1.20801647180543,{"v":6.863005464e-213,"d":"6.86E-213"},"Up",{"v":1.288908e-215,"d":"1.29E-215"},"MCL1","GO:0005759//mitochondrial matrix;GO:0016020//membrane;GO:0097136//Bcl-2 family protein complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005741//mitochondrial outer membrane;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005739//mitochondrion","GO:0015266//protein channel activity;GO:0051434//BH3 domain binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity","GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0001709//cell fate determination;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:1903378//positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway;GO:0034097//response to cytokine;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway;GO:0008637//apoptotic mitochondrial changes;GO:2001020//regulation of response to DNA damage stimulus;GO:0043066//negative regulation of apoptotic process;GO:2000811//negative regulation of anoikis;GO:0019725//cellular homeostasis;GO:0007275//multicellular organism development;GO:0010507//negative regulation of autophagy;GO:0042981//regulation of apoptotic process","K02539//myeloid leukemia cell differntiation protein MCL-1","NP_068779.1//induced myeloid leukemia cell differentiation protein Mcl-1 isoform 1 [Homo sapiens];NP_001184249.1//induced myeloid leukemia cell differentiation protein Mcl-1 isoform 3 [Homo sapiens];NP_877495.1//induced myeloid leukemia cell differentiation protein Mcl-1 isoform 2 [Homo sapiens]","4;1//3;2//1"]
[2785,962,0.26,0.6,1.20645087746743,0.364254405829369,"*",0.225316,"GNG3","NA","NA","NA","K04540//guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3","XP_011798065.1//PREDICTED: guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 [Colobus angolensis palliatus]",4]
[51734,1414,28.46,65.63,1.20541977123669,{"v":1.75764980851064E-57,"d":"1.76E-57"},"Up",{"v":2.0686e-59,"d":"2.07E-59"},"MSRB1","GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0005737//cytoplasm","GO:0003779//actin binding;GO:0046872//metal ion binding;GO:0033743//peptide-methionine (R)-S-oxide reductase activity;GO:0033745//L-methionine-(R)-S-oxide reductase activity;GO:0008270//zinc ion binding;GO:0070191//methionine-R-sulfoxide reductase activity","GO:0006979//response to oxidative stress;GO:0030091//protein repair;GO:0045087//innate immune response;GO:0030041//actin filament polymerization","K07305//peptide-methionine (R)-S-oxide reductase [EC:1.8.4.12]","NP_057416.1//methionine-R-sulfoxide reductase B1 [Homo sapiens]","3//A2MP1"]
[837,1324,2.41,5.55,1.20345462500751,{"v":2.66319558888557e-05,"d":"2.66E-05"},"Up",{"v":5.58014e-06,"d":"5.58E-06"},"CASP4","GO:0005783//endoplasmic reticulum;GO:0072557//IPAF inflammasome complex;GO:0072559//NLRP3 inflammasome complex;GO:0043234//protein complex;GO:0005829//cytosol;GO:0005576//extracellular region;GO:0005789//endoplasmic reticulum membrane;GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0097169//AIM2 inflammasome complex","GO:0050700//CARD domain binding;GO:0097153//cysteine-type endopeptidase activity involved in apoptotic process;GO:0004197//cysteine-type endopeptidase activity","GO:1903265//positive regulation of tumor necrosis factor-mediated signaling pathway;GO:1904646//cellular response to amyloid-beta;GO:0006954//inflammatory response;GO:0006915//apoptotic process;GO:0050727//regulation of inflammatory response;GO:0006508//proteolysis;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0097193//intrinsic apoptotic signaling pathway;GO:0045087//innate immune response;GO:0042981//regulation of apoptotic process","K04394//caspase 4 [EC:3.4.22.57 3.4.22.64]","NP_001216.1//caspase-4 isoform alpha precursor [Homo sapiens]","3//A2MP1;2//1"]
[84226,6218,0.1,0.23,1.20163386116965,0.108839896648192,"*",0.0516332,"C2orf16","GO:0070062//extracellular exosome;GO:0005634//nucleus","NA","NA","K20093//DNA excision repair protein ERCC-6-like [EC:3.6.4.12];K13172//serine/arginine repetitive matrix protein 2","NP_115642.3//uncharacterized protein C2orf16 [Homo sapiens]","3//A2MP1"]
[397,1279,0.2,0.46,1.20163386116965,0.364401922041106,"*",0.225316,"ARHGDIB","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005856//cytoskeleton;GO:0005829//cytosol;GO:0031410//cytoplasmic vesicle;GO:0005737//cytoplasm","GO:0005094//Rho GDP-dissociation inhibitor activity;GO:0048365//Rac GTPase binding;GO:0003924//GTPase activity;GO:0005096//GTPase activator activity","GO:0007162//negative regulation of cell adhesion;GO:2000249//regulation of actin cytoskeleton reorganization;GO:0006928//movement of cell or subcellular component;GO:1901164//negative regulation of trophoblast cell migration;GO:0007275//multicellular organism development;GO:0035023//regulation of Rho protein signal transduction;GO:0071461//cellular response to redox state;GO:0051056//regulation of small GTPase mediated signal transduction","K12462//Rho GDP-dissociation inhibitor","NP_001166.3//rho GDP-dissociation inhibitor 2 [Homo sapiens]","6;1//3"]
[5155,3205,1,2.3,1.20163386116965,0.000711278922537486,"Up",0.0001930258,"PDGFB","GO:0016020//membrane;GO:0031012//extracellular matrix;GO:0005788//endoplasmic reticulum lumen;GO:0016323//basolateral plasma membrane;GO:0005615//extracellular space;GO:0005622//intracellular;GO:0005737//cytoplasm;GO:0009986//cell surface","GO:0005161//platelet-derived growth factor receptor binding;GO:0008083//growth factor activity;GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0048407//platelet-derived growth factor binding;GO:0016176//superoxide-generating NADPH oxidase activator activity;GO:0005518//collagen binding;GO:0042056//chemoattractant activity","GO:1902895//positive regulation of pri-miRNA transcription from RNA polymerase II promoter;GO:0030335//positive regulation of cell migration;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0007596//blood coagulation;GO:0031954//positive regulation of protein autophosphorylation;GO:1904707//positive regulation of vascular smooth muscle cell proliferation;GO:0032091//negative regulation of protein binding;GO:0060326//cell chemotaxis;GO:0071363//cellular response to growth factor stimulus;GO:1904754//positive regulation of vascular associated smooth muscle cell migration;GO:0009611//response to wounding;GO:1905176//positive regulation of vascular smooth muscle cell dedifferentiation;GO:0070528//protein kinase C signaling;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0048146//positive regulation of fibroblast proliferation;GO:0032147//activation of protein kinase activity;GO:0072593//reactive oxygen species metabolic process;GO:0045740//positive regulation of DNA replication;GO:0035655//interleukin-18-mediated signaling pathway;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0072126//positive regulation of glomerular mesangial cell proliferation;GO:0050921//positive regulation of chemotaxis;GO:0018105//peptidyl-serine phosphorylation;GO:1902894//negative regulation of pri-miRNA transcription from RNA polymerase II promoter;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0032148//activation of protein kinase B activity;GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0035793//positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway;GO:0010544//negative regulation of platelet activation;GO:0090280//positive regulation of calcium ion import;GO:0002548//monocyte chemotaxis;GO:0001938//positive regulation of endothelial cell proliferation;GO:0045840//positive regulation of mitotic nuclear division;GO:0018108//peptidyl-tyrosine phosphorylation;GO:1905064//negative regulation of vascular smooth muscle cell differentiation;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0043406//positive regulation of MAP kinase activity;GO:0010512//negative regulation of phosphatidylinositol biosynthetic process;GO:2000573//positive regulation of DNA biosynthetic process;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:1900127//positive regulation of hyaluronan biosynthetic process;GO:0008284//positive regulation of cell proliferation","K17386//platelet-derived growth factor subunit B","XP_019516155.1//PREDICTED: platelet-derived growth factor subunit B isoform X1 [Hipposideros armiger];NP_148937.1//platelet-derived growth factor subunit B isoform 2 [Homo sapiens]","3//A2MP1"]
[8877,1960,4.73,10.86,1.19911201446497,{"v":4.57398727160494E-13,"d":"4.57E-13"},"Up",{"v":3.71096e-14,"d":"3.71E-14"},"SPHK1","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0000287//magnesium ion binding;GO:0003951//NAD+ kinase activity;GO:0003677//DNA binding;GO:0005524//ATP binding;GO:0017050//D-erythro-sphingosine kinase activity;GO:0008481//sphinganine kinase activity;GO:0038036//sphingosine-1-phosphate receptor activity;GO:0005516//calmodulin binding;GO:0051721//protein phosphatase 2A binding","GO:0006670//sphingosine metabolic process;GO:0030335//positive regulation of cell migration;GO:0030307//positive regulation of cell growth;GO:0035556//intracellular signal transduction;GO:0001568//blood vessel development;GO:0010803//regulation of tumor necrosis factor-mediated signaling pathway;GO:0007420//brain development;GO:0032651//regulation of interleukin-1 beta production;GO:0045766//positive regulation of angiogenesis;GO:0006457//protein folding;GO:0007165//signal transduction;GO:0046512//sphingosine biosynthetic process;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0030148//sphingolipid biosynthetic process;GO:0019722//calcium-mediated signaling;GO:0048146//positive regulation of fibroblast proliferation;GO:0045931//positive regulation of mitotic cell cycle;GO:0031398//positive regulation of protein ubiquitination;GO:0043066//negative regulation of apoptotic process;GO:0006954//inflammatory response;GO:0042346//positive regulation of NF-kappaB import into nucleus;GO:0045987//positive regulation of smooth muscle contraction;GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:0046521//sphingoid catabolic process","K04718//sphingosine kinase [EC:2.7.1.91]","XP_008009822.1//PREDICTED: sphingosine kinase 1 isoform X1 [Chlorocebus sabaeus];NP_892010.2//sphingosine kinase 1 isoform 2 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[90853,2571,1.84,4.21,1.19411446700938,{"v":4.10460903798481E-7,"d":"4.10E-07"},"Up",{"v":6.42646e-08,"d":"6.43E-08"},"SPOCD1","NA","NA","GO:0010923//negative regulation of phosphatase activity;GO:0006351//transcription, DNA-templated","K17596//SPOC domain-containing protein 1","NP_001268916.1//SPOC domain-containing protein 1 isoform 2 [Homo sapiens];XP_016858271.1//PREDICTED: SPOC domain-containing protein 1 isoform X4 [Homo sapiens];NP_653170.3//SPOC domain-containing protein 1 isoform 1 [Homo sapiens]","1//3;5"]
[123099,1411,0.35,0.8,1.1926450779424,0.152461624006887,"*",0.0776052,"DEGS2","GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0042284//sphingolipid delta-4 desaturase activity;GO:0000170//sphingosine hydroxylase activity","GO:0006667//sphinganine metabolic process;GO:0030148//sphingolipid biosynthetic process;GO:0046513//ceramide biosynthetic process","K04712//sphingolipid 4-desaturase/C4-monooxygenase [EC:1.14.19.17 1.14.18.5]","XP_001157834.2//PREDICTED: sphingolipid delta(4)-desaturase/C4-monooxygenase DES2 [Pan troglodytes]","2//1"]
[5342,3016,0.28,0.64,1.1926450779424,0.0398970881789137,"*",0.0164169,"PLGLB2","NA","NA","NA","K01315//plasminogen [EC:3.4.21.7]","XP_003820290.1//PREDICTED: plasminogen isoform X1 [Pan paniscus]",4]
[283358,3438,0.07,0.16,1.1926450779424,0.364217545436147,"*",0.225316,"B4GALNT3","GO:0043231//intracellular membrane-bounded organelle;GO:0032580//Golgi cisterna membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane","GO:0033842//N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity;GO:0008376//acetylgalactosaminyltransferase activity","NA","K09656//beta-1,4-N-acetylgalactosaminyltransferase 3 [EC:2.4.1.244]","NP_775864.3//beta-1,4-N-acetylgalactosaminyltransferase 3 [Homo sapiens]","3//A2MP1"]
[25858,764,1.2,2.74,1.19114148735201,0.0470757067223382,"*",0.01976272,"CATSPERZ","GO:0097228//sperm principal piece;GO:0005737//cytoplasm;GO:0036128//CatSper complex","NA","GO:0030317//flagellated sperm motility;GO:0007140//male meiotic nuclear division;GO:0048240//sperm capacitation;GO:0007283//spermatogenesis","K04915//potassium channel subfamily K member 4","NP_001034585.1//cation channel sperm-associated protein subunit zeta [Homo sapiens]","1//3"]
[3269,4298,1.98,4.52,1.19082234233558,{"v":1.03241540269461E-12,"d":"1.03E-12"},"Up",{"v":8.6347e-14,"d":"8.63E-14"},"HRH1","GO:0005887//integral component of plasma membrane;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0004969//histamine receptor activity;GO:0004930//G-protein coupled receptor activity","GO:0008542//visual learning;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway;GO:0048245//eosinophil chemotaxis;GO:0019229//regulation of vasoconstriction;GO:0043114//regulation of vascular permeability;GO:0050804//modulation of chemical synaptic transmission;GO:0006954//inflammatory response;GO:0007613//memory;GO:0045907//positive regulation of vasoconstriction;GO:0048016//inositol phosphate-mediated signaling;GO:0032962//positive regulation of inositol trisphosphate biosynthetic process;GO:0071420//cellular response to histamine;GO:0048167//regulation of synaptic plasticity","K04149//histamine receptor H1","NP_000852.1//histamine H1 receptor [Homo sapiens]","1//3;3//A2MP1"]
[128344,2260,0.25,0.57,1.18903382439002,0.128864676821023,"*",0.0632384,"PIFO","GO:0036064//ciliary basal body;GO:0005634//nucleus;GO:0031410//cytoplasmic vesicle;GO:0005802//trans-Golgi network","GO:0043015//gamma-tubulin binding;GO:0048487//beta-tubulin binding;GO:0008092//cytoskeletal protein binding;GO:0019894//kinesin binding;GO:0017137//Rab GTPase binding;GO:0019901//protein kinase binding","GO:0031344//regulation of cell projection organization;GO:0033674//positive regulation of kinase activity;GO:0030030//cell projection organization","NA","NP_001287760.1//protein pitchfork isoform 2 [Homo sapiens];NP_857594.2//protein pitchfork isoform 1 [Homo sapiens]","1//3;5"]
[2707,1953,0.18,0.41,1.18762700317577,0.150102786873921,"*",0.0761696,"GJB3","GO:0043231//intracellular membrane-bounded organelle;GO:0005921//gap junction;GO:0005922//connexin complex;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0005737//cytoplasm","GO:0005243//gap junction channel activity","GO:0071300//cellular response to retinoic acid;GO:0043588//skin development;GO:0007154//cell communication;GO:0001890//placenta development;GO:0001701//in utero embryonic development;GO:0007283//spermatogenesis","K07622//gap junction beta-3 protein","NP_076872.1//gap junction beta-3 protein [Homo sapiens]","1//3;2//1"]
[6772,4117,41.1,93.57,1.18690765952626,{"v":5.98636708923077e-220,"d":"5.99E-220"},"Up",{"v":9.74368e-223,"d":"9.74E-223"},"STAT1","GO:0030425//dendrite;GO:0030424//axon;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0000983//transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding;GO:0003690//double-stranded DNA binding;GO:0045296//cadherin binding;GO:0004871//signal transducer activity;GO:0019899//enzyme binding;GO:0003700//DNA binding transcription factor activity;GO:0001047//core promoter binding","GO:0007259//JAK-STAT cascade;GO:0034097//response to cytokine;GO:0072308//negative regulation of metanephric nephron tubule epithelial cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0071346//cellular response to interferon-gamma;GO:0035458//cellular response to interferon-beta;GO:0007584//response to nutrient;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0072136//metanephric mesenchymal cell proliferation involved in metanephros development;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0001937//negative regulation of endothelial cell proliferation;GO:0016525//negative regulation of angiogenesis;GO:0043434//response to peptide hormone;GO:0051591//response to cAMP;GO:0006351//transcription, DNA-templated;GO:0006915//apoptotic process;GO:0032869//cellular response to insulin stimulus;GO:0008015//blood circulation;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0072162//metanephric mesenchymal cell differentiation;GO:0008284//positive regulation of cell proliferation","K11220//signal transducer and activator of transcription 1","CAH18430.1//hypothetical protein [Homo sapiens];NP_009330.1//signal transducer and activator of transcription 1-alpha/beta isoform alpha [Homo sapiens]","3//A2MP1;2//1"]
[348938,3240,4.08,9.28,1.18555565315608,{"v":5.57631840677966e-19,"d":"5.58E-19"},"Up",{"v":2.88346e-20,"d":"2.88E-20"},"NIPAL4","NA","NA","NA","K19364//magnesium transporter NIPA1","XP_014200623.1//PREDICTED: magnesium transporter NIPA4 [Pan paniscus]","1//3"]
[722,2256,0.11,0.25,1.18442457113743,0.364291273684211,"*",0.225316,"C4BPA","GO:0005615//extracellular space;GO:0072562//blood microparticle;GO:0044216//other organism cell;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0003723//RNA binding","GO:0006958//complement activation, classical pathway;GO:0030449//regulation of complement activation;GO:0045732//positive regulation of protein catabolic process;GO:0045959//negative regulation of complement activation, classical pathway;GO:1903027//regulation of opsonization;GO:0045087//innate immune response","K04002//complement component 4 binding protein, alpha","NP_000706.1//C4b-binding protein alpha chain precursor [Homo sapiens]","3//A2MP1"]
[100134938,1360,5.36,12.17,1.18302426225596,{"v":1.33403176594427E-10,"d":"1.33E-10"},"Up",{"v":1.34873E-11,"d":"1.35E-11"},"UPK3BL1","NA","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K06245//laminin, beta 4;K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K17630//Ras GTPase-activating protein 4;K12025//tripartite motif-containing protein 52","XP_016868384.1//PREDICTED: uroplakin-3b-like protein isoform X1 [Homo sapiens]","2//1"]
[163732,1312,30.45,69.13,1.18286969751349,{"v":2.102865282e-54,"d":"2.10E-54"},"Up",{"v":2.63286e-56,"d":"2.63E-56"},"CITED4","NA","NA","NA","K21361//Cbp/p300-interacting transactivator 2","XP_021527780.1//LOW QUALITY PROTEIN: cbp/p300-interacting transactivator 4 [Aotus nancymaae]","2//1"]
[5273,2128,0.19,0.43,1.17833724125851,0.15015835991608,"*",0.0761696,"SERPINB10","NA","NA","NA","K13963//serpin B","XP_009250730.1//PREDICTED: serpin B10 [Pongo abelii]","2//1"]
[241,921,0.99,2.24,1.17799830197799,0.0470686878306247,"*",0.01976272,"ALOX5AP","GO:0016020//membrane;GO:0031965//nuclear membrane;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005635//nuclear envelope;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0004051//arachidonate 5-lipoxygenase activity;GO:0047485//protein N-terminus binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0019899//enzyme binding;GO:0008047//enzyme activator activity;GO:0050544//arachidonic acid binding","GO:0002675//positive regulation of acute inflammatory response;GO:0019370//leukotriene biosynthetic process;GO:0006691//leukotriene metabolic process;GO:0002540//leukotriene production involved in inflammatory response;GO:0071277//cellular response to calcium ion;GO:2001300//lipoxin metabolic process;GO:0019372//lipoxygenase pathway;GO:0070207//protein homotrimerization","K20735//arachidonate 5-lipoxygenase-activating protein","NP_001191335.1//arachidonate 5-lipoxygenase-activating protein isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[162993,2054,0.23,0.52,1.17687776208408,0.44747188010085,"*",0.299986,"ZNF846","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","XP_017194262.1//PREDICTED: uncharacterized protein LOC100349966 [Oryctolagus cuniculus];XP_009191705.2//zinc finger protein 846 isoform X2 [Papio anubis];XP_010591673.1//PREDICTED: zinc finger protein 14-like [Loxodonta africana]","1//3;2//1"]
[11054,2445,22.49,50.79,1.17526081283898,{"v":6.77384730909091e-75,"d":"6.77E-75"},"Up",{"v":5.59752E-77,"d":"5.60E-77"},"OGFR","GO:0016020//membrane;GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0004985//opioid receptor activity","GO:0001558//regulation of cell growth","K06568//mucin-1","NP_031372.2//opioid growth factor receptor [Homo sapiens]","3//A2MP1"]
[51561,1049,0.31,0.7,1.17508670655809,0.303528119940349,"*",0.178385,"IL23A","GO:0005788//endoplasmic reticulum lumen;GO:0005576//extracellular region;GO:0070743//interleukin-23 complex","GO:0045519//interleukin-23 receptor binding;GO:0005125//cytokine activity","GO:0042102//positive regulation of T cell proliferation;GO:0032740//positive regulation of interleukin-17 production;GO:0042509//regulation of tyrosine phosphorylation of STAT protein;GO:0045672//positive regulation of osteoclast differentiation;GO:2000330//positive regulation of T-helper 17 cell lineage commitment;GO:0032760//positive regulation of tumor necrosis factor production;GO:0032816//positive regulation of natural killer cell activation;GO:0002827//positive regulation of T-helper 1 type immune response;GO:0045087//innate immune response;GO:0032729//positive regulation of interferon-gamma production;GO:0042104//positive regulation of activated T cell proliferation;GO:0010536//positive regulation of activation of Janus kinase activity;GO:2000318//positive regulation of T-helper 17 type immune response;GO:0032725//positive regulation of granulocyte macrophage colony-stimulating factor production;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0048771//tissue remodeling;GO:0032733//positive regulation of interleukin-10 production;GO:0050829//defense response to Gram-negative bacterium;GO:0032693//negative regulation of interleukin-10 production;GO:0051135//positive regulation of NK T cell activation;GO:0034105//positive regulation of tissue remodeling;GO:0050729//positive regulation of inflammatory response;GO:0032819//positive regulation of natural killer cell proliferation;GO:0043382//positive regulation of memory T cell differentiation;GO:0032735//positive regulation of interleukin-12 production;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0035722//interleukin-12-mediated signaling pathway;GO:0090023//positive regulation of neutrophil chemotaxis;GO:0051607//defense response to virus;GO:0006954//inflammatory response;GO:0042346//positive regulation of NF-kappaB import into nucleus;GO:0051142//positive regulation of NK T cell proliferation;GO:0042098//T cell proliferation;GO:0006955//immune response;GO:0002230//positive regulation of defense response to virus by host","K05426//interleukin 23, alpha subunit p19","NP_057668.1//interleukin-23 subunit alpha precursor [Homo sapiens]","2//1"]
[948,2800,0.04,0.09,1.16992500144231,0.434273696958247,"*",0.287794,"CD36","GO:0005615//extracellular space;GO:0009897//external side of plasma membrane;GO:0016324//apical plasma membrane;GO:0030666//endocytic vesicle membrane;GO:0031526//brush border membrane;GO:0009986//cell surface;GO:0045121//membrane raft;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0045177//apical part of cell;GO:0005581//collagen trimer","GO:0008289//lipid binding;GO:0005041//low-density lipoprotein receptor activity;GO:0001540//amyloid-beta binding;GO:0071813//lipoprotein particle binding;GO:0030169//low-density lipoprotein particle binding;GO:0070892//lipoteichoic acid receptor activity;GO:0008035//high-density lipoprotein particle binding","GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0010744//positive regulation of macrophage derived foam cell differentiation;GO:0060100//positive regulation of phagocytosis, engulfment;GO:0007596//blood coagulation;GO:0070543//response to linoleic acid;GO:0031623//receptor internalization;GO:0071222//cellular response to lipopolysaccharide;GO:2000334//positive regulation of blood microparticle formation;GO:0007166//cell surface receptor signaling pathway;GO:0032760//positive regulation of tumor necrosis factor production;GO:0071221//cellular response to bacterial lipopeptide;GO:0010886//positive regulation of cholesterol storage;GO:0050909//sensory perception of taste;GO:0034197//triglyceride transport;GO:0010628//positive regulation of gene expression;GO:0043277//apoptotic cell clearance;GO:2000121//regulation of removal of superoxide radicals;GO:0044130//negative regulation of growth of symbiont in host;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0030299//intestinal cholesterol absorption;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0030194//positive regulation of blood coagulation;GO:0050702//interleukin-1 beta secretion;GO:0032755//positive regulation of interleukin-6 production;GO:0071447//cellular response to hydroperoxide;GO:0006910//phagocytosis, recognition;GO:0042992//negative regulation of transcription factor import into nucleus;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0032735//positive regulation of interleukin-12 production;GO:1900227//positive regulation of NLRP3 inflammasome complex assembly;GO:1990000//amyloid fibril formation;GO:0070508//cholesterol import;GO:0050830//defense response to Gram-positive bacterium;GO:0042953//lipoprotein transport;GO:0060907//positive regulation of macrophage cytokine production;GO:0044539//long-chain fatty acid import;GO:0034383//low-density lipoprotein particle clearance;GO:0035634//response to stilbenoid;GO:0071223//cellular response to lipoteichoic acid;GO:0055096//low-density lipoprotein particle mediated signaling;GO:1904646//cellular response to amyloid-beta;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0019915//lipid storage;GO:0006955//immune response;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:2000505//regulation of energy homeostasis","K06259//CD36 antigen","NP_001276838.1//platelet glycoprotein 4 isoform 3 [Homo sapiens];NP_001001547.1//platelet glycoprotein 4 isoform 1 [Homo sapiens];NP_001276837.1//platelet glycoprotein 4 isoform 2 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[116449,5602,0.08,0.18,1.16992500144231,0.18187033614889,"*",0.0954324,"CLNK","GO:0005622//intracellular","GO:0005070//SH3/SH2 adaptor activity","GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0006955//immune response;GO:0035556//intracellular signal transduction","K07361//lymphocyte cytosolic protein 2","XP_011512077.1//PREDICTED: cytokine-dependent hematopoietic cell linker isoform X1 [Homo sapiens]","3//A2MP1"]
[7161,5140,0.08,0.18,1.16992500144231,0.251376765867138,"*",0.1423692,"TP73","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000785//chromatin;GO:0030054//cell junction;GO:0005737//cytoplasm;GO:0005667//transcription factor complex;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0005739//mitochondrion","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0002039//p53 binding;GO:0042802//identical protein binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0019901//protein kinase binding;GO:0046872//metal ion binding;GO:0003684//damaged DNA binding;GO:0003682//chromatin binding;GO:0043565//sequence-specific DNA binding;GO:0008134//transcription factor binding;GO:0003700//DNA binding transcription factor activity;GO:0097371//MDM2/MDM4 family protein binding","GO:0060044//negative regulation of cardiac muscle cell proliferation;GO:0007346//regulation of mitotic cell cycle;GO:0048714//positive regulation of oligodendrocyte differentiation;GO:0010332//response to gamma radiation;GO:0034644//cellular response to UV;GO:0043065//positive regulation of apoptotic process;GO:0008285//negative regulation of cell proliferation;GO:0042493//response to drug;GO:1900740//positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway;GO:0043524//negative regulation of neuron apoptotic process;GO:0051262//protein tetramerization;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0016032//viral process;GO:0006915//apoptotic process;GO:1901796//regulation of signal transduction by p53 class mediator;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:1902036//regulation of hematopoietic stem cell differentiation;GO:0031571//mitotic G1 DNA damage checkpoint;GO:0010468//regulation of gene expression;GO:0001822//kidney development;GO:0007050//cell cycle arrest;GO:0043508//negative regulation of JUN kinase activity;GO:0045893//positive regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006974//cellular response to DNA damage stimulus;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0000187//activation of MAPK activity;GO:0010243//response to organonitrogen compound;GO:0010165//response to X-ray;GO:0006298//mismatch repair;GO:0006351//transcription, DNA-templated;GO:0045665//negative regulation of neuron differentiation;GO:0071158//positive regulation of cell cycle arrest;GO:0042981//regulation of apoptotic process;GO:0006978//DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator","K10148//tumor protein p73","NP_005418.1//tumor protein p73 isoform a [Homo sapiens];NP_001191115.1//tumor protein p73 isoform j [Homo sapiens];NP_001191117.1//tumor protein p73 isoform l [Homo sapiens];NP_001119713.1//tumor protein p73 isoform c [Homo sapiens];NP_001191113.1//tumor protein p73 isoform h [Homo sapiens];XP_008572777.1//PREDICTED: tumor protein p73 isoform X1 [Galeopterus variegatus];NP_001191120.1//tumor protein p73 isoform g [Homo sapiens];NP_001191119.1//tumor protein p73 isoform f [Homo sapiens];XP_007979055.1//PREDICTED: tumor protein p73 isoform X7 [Chlorocebus sabaeus];NP_001191116.1//tumor protein p73 isoform k [Homo sapiens];NP_001119712.1//tumor protein p73 isoform b [Homo sapiens]","1//3;3//A2MP1;2//1"]
[80757,1551,6.26,14.08,1.16941277170468,{"v":2.01164718693227E-13,"d":"2.01E-13"},"Up",{"v":1.580454e-14,"d":"1.58E-14"},"TMEM121","GO:0016021//integral component of membrane","NA","NA","K16628//collagen, type VII, alpha;K11253//histone H3","NP_079544.1//transmembrane protein 121 [Homo sapiens]","1//3;3//A2MP1"]
[55509,992,9.63,21.51,1.1593998215796,{"v":8.58707829691032e-13,"d":"8.59E-13"},"Up",{"v":7.1335e-14,"d":"7.13E-14"},"BATF3","GO:0005634//nucleus","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003714//transcription corepressor activity;GO:0003700//DNA binding transcription factor activity;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0097028//dendritic cell differentiation;GO:0009615//response to virus;GO:0043011//myeloid dendritic cell differentiation;GO:0006366//transcription from RNA polymerase II promoter","K09034//ATF-like basic leucine zipper transcriptional factor","NP_061134.1//basic leucine zipper transcriptional factor ATF-like 3 [Homo sapiens]","2//1"]
[200879,2478,3.64,8.12,1.15754127698648,{"v":1.92427701138686e-12,"d":"1.92E-12"},"Up",{"v":1.650344e-13,"d":"1.65E-13"},"LIPH","GO:0005615//extracellular space;GO:0005886//plasma membrane","GO:0004620//phospholipase activity;GO:0052689//carboxylic ester hydrolase activity;GO:0008201//heparin binding","GO:0016042//lipid catabolic process;GO:0006654//phosphatidic acid biosynthetic process","K19404//phosphatidic acid-selective&#160;phospholipase A1 [EC:3.1.1.-]","NP_640341.1//lipase member H precursor [Homo sapiens]","2//1"]
[83854,1779,1.36,3.03,1.15571114222261,4.12433834849952E-4,"Up",1.066844E-4,"ANGPTL6","GO:0070062//extracellular exosome;GO:0030141//secretory granule","NA","NA","K05467//angiopoietin 4","XP_005260148.1//PREDICTED: angiopoietin-related protein 6 isoform X2 [Homo sapiens];XP_011526650.1//PREDICTED: angiopoietin-related protein 6 isoform X3 [Homo sapiens]","1//3;2//1"]
[834,1481,0.09,0.2,1.15200309344505,0.529759689468548,"*",0.37379,"CASP1","GO:0072557//IPAF inflammasome complex;GO:0072559//NLRP3 inflammasome complex;GO:0097179//protease inhibitor complex;GO:0043234//protein complex;GO:0005829//cytosol;GO:0072558//NLRP1 inflammasome complex;GO:0005576//extracellular region;GO:0005739//mitochondrion;GO:0097169//AIM2 inflammasome complex","GO:0004175//endopeptidase activity;GO:0050700//CARD domain binding;GO:0097153//cysteine-type endopeptidase activity involved in apoptotic process;GO:0042802//identical protein binding;GO:0004197//cysteine-type endopeptidase activity;GO:0008656//cysteine-type endopeptidase activator activity involved in apoptotic process;GO:0019900//kinase binding","GO:0033198//response to ATP;GO:0071260//cellular response to mechanical stimulus;GO:0051882//mitochondrial depolarization;GO:0071222//cellular response to lipopolysaccharide;GO:0032611//interleukin-1 beta production;GO:0071310//cellular response to organic substance;GO:0071346//cellular response to interferon-gamma;GO:1901998//toxin transport;GO:0097300//programmed necrotic cell death;GO:0010506//regulation of autophagy;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0016540//protein autoprocessing;GO:0070269//pyroptosis;GO:0007165//signal transduction;GO:0050718//positive regulation of interleukin-1 beta secretion;GO:0050717//positive regulation of interleukin-1 alpha secretion;GO:1903265//positive regulation of tumor necrosis factor-mediated signaling pathway;GO:0001666//response to hypoxia;GO:0006915//apoptotic process;GO:0060081//membrane hyperpolarization;GO:0050727//regulation of inflammatory response;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0006508//proteolysis;GO:0042981//regulation of apoptotic process","K01370//caspase 1 [EC:3.4.22.36]","XP_018893204.1//PREDICTED: caspase-1 isoform X1 [Gorilla gorilla gorilla];NP_150637.1//caspase-1 isoform epsilon [Homo sapiens];NP_150635.1//caspase-1 isoform gamma [Homo sapiens];NP_150636.1//caspase-1 isoform delta [Homo sapiens]","4;3//A2MP1;2//1"]
[285346,1970,0.09,0.2,1.15200309344505,0.433863850132125,"*",0.287794,"ZNF852","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_011737277.1//PREDICTED: zinc finger protein with KRAB and SCAN domains 7 isoform X3 [Macaca nemestrina]","1//3"]
[10485,802,0.33,0.73,1.14543043952156,0.364512637634191,"*",0.225316,"C1orf61","GO:0005634//nucleus","NA","GO:0045944//positive regulation of transcription from RNA polymerase II promoter","NA","NP_001307383.1//protein CROC-4 isoform 3 [Homo sapiens];NP_006356.1//protein CROC-4 isoform 1 [Homo sapiens];XP_017803429.1//uncharacterized protein LOC101005783 isoform X4 [Papio anubis];NP_001307384.1//protein CROC-4 isoform 4 [Homo sapiens]","1//3;2//1"]
[65249,4339,2.39,5.27,1.14079234365647,{"v":7.27083014930271e-14,"d":"7.27E-14"},"Up",{"v":5.54848e-15,"d":"5.55E-15"},"ZSWIM4","NA","GO:0008270//zinc ion binding","NA","K16628//collagen, type VII, alpha;K01231//alpha-mannosidase II [EC:3.2.1.114]","NP_075560.2//zinc finger SWIM domain-containing protein 4 [Homo sapiens]","2//1"]
[100287036,1443,0.79,1.74,1.13916274767163,0.0284454637110436,"*",0.01114206,"LOC100287036","NA","NA","NA","NA","XP_011916790.1//PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein LOC105586224, partial [Cercocebus atys]","2//1"]
[163175,2906,0.05,0.11,1.13750352374993,0.609503803616698,"*",0.451538,"LGI4","GO:0005615//extracellular space;GO:0005576//extracellular region","NA","GO:0031641//regulation of myelination;GO:0014009//glial cell proliferation;GO:0008344//adult locomotory behavior;GO:0042551//neuron maturation;GO:0022011//myelination in peripheral nervous system","K19999//leucine-rich repeat LGI family member 3","NP_644813.1//leucine-rich repeat LGI family member 4 precursor [Homo sapiens]","2//1"]
[23630,1487,0.05,0.11,1.13750352374993,0.73580230124843,"*",0.623548,"KCNE5","GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex","GO:0005249//voltage-gated potassium channel activity;GO:0044325//ion channel binding;GO:0015459//potassium channel regulator activity;GO:0086008//voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization","GO:0086005//ventricular cardiac muscle cell action potential;GO:0086013//membrane repolarization during cardiac muscle cell action potential;GO:1901381//positive regulation of potassium ion transmembrane transport;GO:1901380//negative regulation of potassium ion transmembrane transport;GO:0086091//regulation of heart rate by cardiac conduction;GO:1901379//regulation of potassium ion transmembrane transport;GO:2001257//regulation of cation channel activity;GO:0060306//regulation of membrane repolarization;GO:0008016//regulation of heart contraction;GO:0086014//atrial cardiac muscle cell action potential;GO:0060048//cardiac muscle contraction;GO:0060372//regulation of atrial cardiac muscle cell membrane repolarization;GO:0071435//potassium ion export;GO:0071805//potassium ion transmembrane transport;GO:0060307//regulation of ventricular cardiac muscle cell membrane repolarization","K04895//potassium voltage-gated channel Isk-related subfamily E member 1-like","NP_036414.1//potassium voltage-gated channel subfamily E regulatory beta subunit 5 [Homo sapiens]","3//A2MP1"]
[165186,3399,0.05,0.11,1.13750352374993,0.608989193853428,"*",0.451538,"TOGARAM2","NA","NA","NA","K22020//mucin-19","NP_001308468.1//TOG array regulator of axonemal microtubules protein 2 isoform 3 [Homo sapiens];XP_018877121.1//PREDICTED: protein FAM179A [Gorilla gorilla gorilla];NP_001308467.1//TOG array regulator of axonemal microtubules protein 2 isoform 2 [Homo sapiens]","1//3;2//1"]
[283514,4005,0.05,0.11,1.13750352374993,0.433986722930237,"*",0.287794,"SIAH3","NA","NA","NA","K02184//formin 2","XP_012638173.1//seven in absentia homolog 3 [Microcebus murinus]","2//1"]
[23414,4507,0.05,0.11,1.13750352374993,0.495712655178669,"*",0.342164,"ZFPM2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0001105//RNA polymerase II transcription coactivator activity;GO:0001085//RNA polymerase II transcription factor binding;GO:0003676//nucleic acid binding;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0008270//zinc ion binding;GO:0008134//transcription factor binding","GO:0003148//outflow tract septum morphogenesis;GO:0030324//lung development;GO:0060412//ventricular septum morphogenesis;GO:0007596//blood coagulation;GO:0006355//regulation of transcription, DNA-templated;GO:2000020//positive regulation of male gonad development;GO:0048568//embryonic organ development;GO:0001570//vasculogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0003221//right ventricular cardiac muscle tissue morphogenesis;GO:0006351//transcription, DNA-templated;GO:0001701//in utero embryonic development;GO:0045599//negative regulation of fat cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:2000195//negative regulation of female gonad development;GO:0060548//negative regulation of cell death;GO:0007506//gonadal mesoderm development","K17442//zinc finger protein ZFPM2","NP_036214.2//zinc finger protein ZFPM2 [Homo sapiens]","3//A2MP1"]
[168455,6827,3.87,8.5,1.13512927488065,{"v":7.8308562855615e-34,"d":"7.83E-34"},"Up",{"v":1.833442E-35,"d":"1.83E-35"},"CCDC71L","NA","NA","GO:0044255//cellular lipid metabolic process;GO:0045600//positive regulation of fat cell differentiation","K06237//collagen, type IV, alpha;K13172//serine/arginine repetitive matrix protein 2","NP_787080.2//coiled-coil domain-containing protein 71L [Homo sapiens]",5]
[10158,894,3.8,8.34,1.13404796511372,{"v":6.81022934747418e-05,"d":"6.81E-05"},"Up",{"v":1.527548e-05,"d":"1.53E-05"},"PDZK1IP1","NA","NA","NA","NA","XP_003921637.2//PREDICTED: PDZK1-interacting protein 1 [Saimiri boliviensis boliviensis]","3//A2MP1"]
[2537,844,6.67,14.63,1.1331711029539,{"v":1.53061075E-7,"d":"1.53E-07"},"Up",{"v":2.25366E-8,"d":"2.25E-08"},"IFI6","GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005886//plasma membrane","NA","GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0060337//type I interferon signaling pathway;GO:0051902//negative regulation of mitochondrial depolarization;GO:0006955//immune response;GO:0001836//release of cytochrome c from mitochondria","NA","XP_012353995.1//PREDICTED: interferon alpha-inducible protein 6 isoform X3 [Nomascus leucogenys];XP_012353994.1//PREDICTED: interferon alpha-inducible protein 6 isoform X2 [Nomascus leucogenys];XP_012353996.1//PREDICTED: interferon alpha-inducible protein 6 isoform X4 [Nomascus leucogenys]","3//A2MP1;2//1"]
[400581,1313,0.62,1.35,1.12261928666396,0.105005540093023,"*",0.0494658,"GRAPL","NA","NA","NA","K04364//growth factor receptor-binding protein 2","XP_002747899.2//PREDICTED: GRB2-related adapter protein [Callithrix jacchus]","1//3;2//1"]
[256126,946,0.52,1.13,1.1197392442741,0.211431989764965,"*",0.1143194,"SYCE2","GO:0005634//nucleus;GO:0000801//central element","NA","GO:0007130//synaptonemal complex assembly;GO:0051301//cell division","K19535//synaptonemal complex central element protein 2","NP_001099048.1//synaptonemal complex central element protein 2 [Homo sapiens]","1//3"]
[3356,4702,0.06,0.13,1.11547721741994,0.364475724962025,"*",0.225316,"HTR2A","GO:0043198//dendritic shaft;GO:0030424//axon;GO:0005901//caveola;GO:0005887//integral component of plasma membrane;GO:0005829//cytosol;GO:0031410//cytoplasmic vesicle;GO:0070852//cell body fiber;GO:0005622//intracellular;GO:0005886//plasma membrane;GO:0043025//neuronal cell body","GO:0051378//serotonin binding;GO:0004993//G-protein coupled serotonin receptor activity;GO:0001965//G-protein alpha-subunit binding;GO:0008144//drug binding;GO:0001618//virus receptor activity;GO:0032403//protein complex binding;GO:0030594//neurotransmitter receptor activity;GO:0071886//1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding","GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0043267//negative regulation of potassium ion transport;GO:0050795//regulation of behavior;GO:0014059//regulation of dopamine secretion;GO:0045821//positive regulation of glycolytic process;GO:0007208//phospholipase C-activating serotonin receptor signaling pathway;GO:0051967//negative regulation of synaptic transmission, glutamatergic;GO:0007610//behavior;GO:0042493//response to drug;GO:0045600//positive regulation of fat cell differentiation;GO:0014832//urinary bladder smooth muscle contraction;GO:0007202//activation of phospholipase C activity;GO:0033674//positive regulation of kinase activity;GO:0014824//artery smooth muscle contraction;GO:0051209//release of sequestered calcium ion into cytosol;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0001659//temperature homeostasis;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0007210//serotonin receptor signaling pathway;GO:0045907//positive regulation of vasoconstriction;GO:0006874//cellular calcium ion homeostasis;GO:0050965//detection of temperature stimulus involved in sensory perception of pain;GO:0048148//behavioral response to cocaine;GO:0043406//positive regulation of MAP kinase activity;GO:0010513//positive regulation of phosphatidylinositol biosynthetic process;GO:0044380//protein localization to cytoskeleton;GO:0046883//regulation of hormone secretion;GO:0006939//smooth muscle contraction;GO:0008219//cell death;GO:0007568//aging;GO:0007613//memory;GO:0007268//chemical synaptic transmission;GO:0050966//detection of mechanical stimulus involved in sensory perception of pain;GO:0030431//sleep;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0008284//positive regulation of cell proliferation","K04157//5-hydroxytryptamine receptor 2","NP_000612.1//5-hydroxytryptamine receptor 2A isoform 1 [Homo sapiens];XP_008050943.2//5-hydroxytryptamine receptor 2A isoform X2 [Carlito syrichta]","4;2//1"]
[339541,1698,0.24,0.52,1.11547721741994,0.251432349452736,"*",0.1423692,"C1orf228","NA","NA","NA","K03575//A/G-specific adenine glycosylase [EC:3.2.2.-]","NP_001139108.1//uncharacterized protein C1orf228 [Homo sapiens]","1//3"]
[9111,1501,8.25,17.85,1.11345804978328,{"v":3.55338875862069e-15,"d":"3.55E-15"},"Up",{"v":2.45138e-16,"d":"2.45E-16"},"NMI","GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0042802//identical protein binding;GO:0003712//transcription cofactor activity","GO:0045824//negative regulation of innate immune response;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0007259//JAK-STAT cascade;GO:0006366//transcription from RNA polymerase II promoter;GO:0006954//inflammatory response;GO:0045355//negative regulation of interferon-alpha biosynthetic process;GO:1902524//positive regulation of protein K48-linked ubiquitination;GO:0045358//negative regulation of interferon-beta biosynthetic process","K15261//poly [ADP-ribose] polymerase 10/14/15 [EC:2.4.2.30]","XP_526097.3//PREDICTED: N-myc-interactor isoform X1 [Pan troglodytes]","2//1"]
[80323,4033,1.24,2.68,1.1118928800709,{"v":7.40708718952234e-07,"d":"7.41E-07"},"Up",{"v":1.203756E-7,"d":"1.20E-07"},"CCDC68","NA","NA","NA","K22031//myocardial zonula adherens protein","NP_079490.1//coiled-coil domain-containing protein 68 [Homo sapiens]","1//3;2//1"]
[56829,5046,17.91,38.4,1.10034097362256,{"v":4.65204255278688E-144,"d":"4.65E-144"},"Up",{"v":1.776478e-146,"d":"1.78E-146"},"ZC3HAV1","NA","GO:0046872//metal ion binding;GO:0003950//NAD+ ADP-ribosyltransferase activity","NA","K15259//poly [ADP-ribose] polymerase 7/11/12/13 [EC:2.4.2.30]","CAE11868.1//hypothetical protein [Homo sapiens]","3//A2MP1"]
[160492,2504,0.21,0.45,1.09953567355091,0.15248037697417,"*",0.0776052,"LMNTD1","GO:0005635//nuclear envelope;GO:0005882//intermediate filament;GO:0005737//cytoplasm","GO:0005198//structural molecule activity","GO:0008283//cell proliferation","K12581//CCR4-NOT transcription complex subunit 7/8;K06245//laminin, beta 4;K07611//lamin B;K02927//large subunit ribosomal protein L40e;K17985//activating molecule in BECN1-regulated autophagy protein 1;K12641//lamin A/C","NP_001139201.1//lamin tail domain-containing protein 1 isoform 4 [Homo sapiens];NP_001139200.1//lamin tail domain-containing protein 1 isoform 1 [Homo sapiens];NP_001139199.1//lamin tail domain-containing protein 1 isoform 3 [Homo sapiens];NP_689803.2//lamin tail domain-containing protein 1 isoform 2 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[730,5964,0.21,0.45,1.09953567355091,0.0370074899123212,"*",0.01506108,"C7","GO:0070062//extracellular exosome;GO:0005579//membrane attack complex;GO:0005576//extracellular region","NA","GO:0006958//complement activation, classical pathway;GO:0030449//regulation of complement activation;GO:0006956//complement activation;GO:0019835//cytolysis;GO:0006955//immune response;GO:0006957//complement activation, alternative pathway;GO:0006883//cellular sodium ion homeostasis","K03996//complement component 7","NP_000578.2//complement component C7 precursor [Homo sapiens]","3//A2MP1"]
[5655,2997,0.14,0.3,1.09953567355091,0.251404554587663,"*",0.1423692,"KLK10","GO:0005576//extracellular region","GO:0004252//serine-type endopeptidase activity;GO:0008236//serine-type peptidase activity","GO:0007049//cell cycle","K09619//kallikrein 10 [EC:3.4.21.-]","NP_002767.2//kallikrein-10 preproprotein [Homo sapiens];XP_007995926.1//PREDICTED: kallikrein-10 isoform X4 [Chlorocebus sabaeus]","1//3;4;2//1"]
[650,3191,0.35,0.75,1.09953567355091,0.0385909874224599,"*",0.01581182,"BMP2","GO:0043231//intracellular membrane-bounded organelle;GO:0005615//extracellular space;GO:0009986//cell surface;GO:0005576//extracellular region;GO:0070724//BMP receptor complex","GO:0008083//growth factor activity;GO:0005125//cytokine activity;GO:0019211//phosphatase activator activity;GO:0004745//retinol dehydrogenase activity;GO:0039706//co-receptor binding;GO:0070700//BMP receptor binding","GO:0060129//thyroid-stimulating hormone-secreting cell differentiation;GO:1902895//positive regulation of pri-miRNA transcription from RNA polymerase II promoter;GO:0001649//osteoblast differentiation;GO:0045666//positive regulation of neuron differentiation;GO:0030335//positive regulation of cell migration;GO:0035054//embryonic heart tube anterior/posterior pattern specification;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0003203//endocardial cushion morphogenesis;GO:0008285//negative regulation of cell proliferation;GO:0055007//cardiac muscle cell differentiation;GO:0042482//positive regulation of odontogenesis;GO:0045600//positive regulation of fat cell differentiation;GO:0060804//positive regulation of Wnt signaling pathway by BMP signaling pathway;GO:0030509//BMP signaling pathway;GO:0001666//response to hypoxia;GO:0042475//odontogenesis of dentin-containing tooth;GO:0042487//regulation of odontogenesis of dentin-containing tooth;GO:0060128//corticotropin hormone secreting cell differentiation;GO:0007219//Notch signaling pathway;GO:0003130//BMP signaling pathway involved in heart induction;GO:0033690//positive regulation of osteoblast proliferation;GO:0021978//telencephalon regionalization;GO:0055008//cardiac muscle tissue morphogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0071407//cellular response to organic cyclic compound;GO:0048839//inner ear development;GO:0003181//atrioventricular valve morphogenesis;GO:0031648//protein destabilization;GO:0045165//cell fate commitment;GO:0030282//bone mineralization;GO:0061036//positive regulation of cartilage development;GO:0000187//activation of MAPK activity;GO:0006029//proteoglycan metabolic process;GO:0072138//mesenchymal cell proliferation involved in ureteric bud development;GO:0001701//in utero embryonic development;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0045669//positive regulation of osteoblast differentiation;GO:0006954//inflammatory response;GO:0009887//animal organ morphogenesis;GO:0048711//positive regulation of astrocyte differentiation;GO:0060039//pericardium development","K21283//bone morphogenetic protein 2","NP_001191.1//bone morphogenetic protein 2 preproprotein [Homo sapiens]","3//A2MP1"]
[9242,2075,28.95,61.95,1.09754093415137,{"v":2.92836243287671e-69,"d":"2.93E-69"},"Up",{"v":2.67648e-71,"d":"2.68E-71"},"MSC","GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0003714//transcription corepressor activity;GO:0001206//transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0046983//protein dimerization activity","GO:1990830//cellular response to leukemia inhibitory factor;GO:0060539//diaphragm development;GO:0014707//branchiomeric skeletal muscle development;GO:0060021//palate development;GO:0006366//transcription from RNA polymerase II promoter","K09072//musculin (activated B-cell factor-1)","NP_005089.2//musculin [Homo sapiens]","3//A2MP1"]
[81606,2956,20.1,42.88,1.09310940439148,{"v":2.24852153866667e-68,"d":"2.25E-68"},"Up",{"v":2.11142e-70,"d":"2.11E-70"},"LBH","GO:0005634//nucleus;GO:0005737//cytoplasm","NA","GO:2000103//positive regulation of mammary stem cell proliferation;GO:0010468//regulation of gene expression;GO:1904677//positive regulation of somatic stem cell division;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:2000737//negative regulation of stem cell differentiation;GO:0030193//regulation of blood coagulation;GO:0007275//multicellular organism development;GO:0060644//mammary gland epithelial cell differentiation;GO:1904674//positive regulation of somatic stem cell population maintenance;GO:0033147//negative regulation of intracellular estrogen receptor signaling pathway","NA","AAG23758.1//PP2281 [Homo sapiens]","3//A2MP1"]
[440689,495,0.68,1.45,1.0924462487646,0.255172732386301,"*",0.1450622,"HIST2H2BF","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0000786//nucleosome","GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity","GO:0006334//nucleosome assembly","K11252//histone H2B","XP_012998546.1//PREDICTED: histone H2B type 2-F isoform X1 [Cavia porcellus];XP_004026583.1//PREDICTED: histone H2B type 2-F-like [Gorilla gorilla gorilla]","4;1//3"]
[100505385,2384,5.58,11.89,1.09141168791647,{"v":1.0210111065033e-15,"d":"1.02E-15"},"Up",{"v":6.7816e-17,"d":"6.78E-17"},"IQCJ-SCHIP1","NA","NA","NA","K21125//mucin-5AC","XP_016795461.1//PREDICTED: schwannomin-interacting protein 1 isoform X3 [Pan troglodytes];XP_016795459.1//PREDICTED: schwannomin-interacting protein 1 isoform X1 [Pan troglodytes]","1//3"]
[158866,6030,0.08,0.17,1.08746284125034,0.285745159771231,"*",0.1657694,"ZDHHC15","GO:0070062//extracellular exosome;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane","GO:0016409//palmitoyltransferase activity;GO:0019706//protein-cysteine S-palmitoyltransferase activity","GO:0018345//protein palmitoylation;GO:0045184//establishment of protein localization;GO:0016188//synaptic vesicle maturation","K20028//palmitoyltransferase ZDHHC2/15/20 [EC:2.3.1.225]","XP_008247070.1//PREDICTED: LOW QUALITY PROTEIN: palmitoyltransferase ZDHHC15 [Oryctolagus cuniculus];NP_001139729.1//palmitoyltransferase ZDHHC15 isoform 3 [Homo sapiens]","1//3;2//1"]
[143162,4946,0.08,0.17,1.08746284125034,0.608732214701663,"*",0.451538,"FRMPD2","GO:0005856//cytoskeleton;GO:0016323//basolateral plasma membrane;GO:0005923//bicellular tight junction;GO:0005737//cytoplasm","GO:0005545//1-phosphatidylinositol binding","GO:0070830//bicellular tight junction assembly","K02374//tyrosine-protein phosphatase non-receptor type 13","NP_001018081.3//FERM and PDZ domain-containing protein 2 isoform 3 [Homo sapiens];NP_001305120.1//FERM and PDZ domain-containing protein 2 isoform 5 precursor [Homo sapiens];NP_001035977.2//FERM and PDZ domain-containing protein 2 isoform 4 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[285679,1208,0.42,0.89,1.08341600818764,0.211456472394627,"*",0.1143194,"C5orf60","GO:0016021//integral component of membrane","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K17985//activating molecule in BECN1-regulated autophagy protein 1;K12025//tripartite motif-containing protein 52","NP_001292317.1//putative uncharacterized protein FLJ35723 isoform a [Homo sapiens];NP_001135778.1//putative uncharacterized protein FLJ35723 isoform b [Homo sapiens]","1//3;2//1"]
[135,2555,0.36,0.76,1.07800251200127,0.088002733069685,"*",0.0403984,"ADORA2A","GO:0030425//dendrite;GO:0048786//presynaptic active zone;GO:0098794//postsynapse;GO:0005622//intracellular;GO:0005882//intermediate filament;GO:0030673//axolemma;GO:0014069//postsynaptic density;GO:0043025//neuronal cell body;GO:0012505//endomembrane system;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0099056//integral component of presynaptic membrane;GO:0005886//plasma membrane;GO:0099055//integral component of postsynaptic membrane","GO:0001609//G-protein coupled adenosine receptor activity;GO:0042802//identical protein binding;GO:0051393//alpha-actinin binding;GO:0046982//protein heterodimerization activity;GO:0031802//type 5 metabotropic glutamate receptor binding;GO:0019899//enzyme binding","GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0014049//positive regulation of glutamate secretion;GO:0050728//negative regulation of inflammatory response;GO:0014057//positive regulation of acetylcholine secretion, neurotransmission;GO:0031000//response to caffeine;GO:0043116//negative regulation of vascular permeability;GO:0051968//positive regulation of synaptic transmission, glutamatergic;GO:0030819//positive regulation of cAMP biosynthetic process;GO:0008285//negative regulation of cell proliferation;GO:0040013//negative regulation of locomotion;GO:0042493//response to drug;GO:0043524//negative regulation of neuron apoptotic process;GO:0045938//positive regulation of circadian sleep/wake cycle, sleep;GO:0006915//apoptotic process;GO:2001235//positive regulation of apoptotic signaling pathway;GO:0008015//blood circulation;GO:0007271//synaptic transmission, cholinergic;GO:0001975//response to amphetamine;GO:0032230//positive regulation of synaptic transmission, GABAergic;GO:0035249//synaptic transmission, glutamatergic;GO:0048167//regulation of synaptic plasticity;GO:0046636//negative regulation of alpha-beta T cell activation;GO:0006355//regulation of transcription, DNA-templated;GO:0051924//regulation of calcium ion transport;GO:0048812//neuron projection morphogenesis;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0060079//excitatory postsynaptic potential;GO:0042311//vasodilation;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0060080//inhibitory postsynaptic potential;GO:0042755//eating behavior;GO:0060134//prepulse inhibition;GO:0050714//positive regulation of protein secretion;GO:0006469//negative regulation of protein kinase activity;GO:0007626//locomotory behavior;GO:0035815//positive regulation of renal sodium excretion;GO:0051899//membrane depolarization;GO:0001963//synaptic transmission, dopaminergic;GO:0014061//regulation of norepinephrine secretion;GO:0035810//positive regulation of urine volume;GO:0051881//regulation of mitochondrial membrane potential;GO:0048143//astrocyte activation","K04266//adenosine receptor A2a","NP_000666.2//adenosine receptor A2a [Homo sapiens]","1//3;5"]
[6442,1089,0.68,1.43,1.07240849552805,0.125179909745708,"*",0.0607092,"SGCA","NA","NA","NA","K12565//alpha-sarcoglycan","XP_011523425.2//PREDICTED: alpha-sarcoglycan isoform X4 [Homo sapiens];XP_003817508.2//PREDICTED: alpha-sarcoglycan isoform X2 [Pan paniscus]","3//A2MP1;2//1"]
[2355,4015,40.01,84.03,1.07054385545006,{"v":2.90505686210526e-176,"d":"2.91E-176"},"Up",{"v":6.91074e-179,"d":"6.91E-179"},"FOSL2","GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0003677//DNA binding;GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA binding transcription factor activity","GO:0003334//keratinocyte development;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0048146//positive regulation of fibroblast proliferation;GO:0008219//cell death","K09030//fos-like antigen 2","NP_005244.1//fos-related antigen 2 [Homo sapiens]","3//A2MP1"]
[116729,805,0.1,0.21,1.0703893278914,0.732555398396705,"*",0.623548,"PPP1R27","NA","GO:0019902//phosphatase binding","GO:0010923//negative regulation of phosphatase activity","K17566//protein phosphatase 1 regulatory subunit 27","XP_008011466.1//PREDICTED: protein phosphatase 1 regulatory subunit 27 [Chlorocebus sabaeus]","3//A2MP1"]
[91694,3530,1.73,3.62,1.06521765944648,{"v":2.43351764521452e-07,"d":"2.43E-07"},"Up",{"v":3.69278e-08,"d":"3.69E-08"},"LONRF1","GO:0005829//cytosol;GO:0005622//intracellular","GO:0061630//ubiquitin protein ligase activity;GO:0046872//metal ion binding;GO:0004842//ubiquitin-protein transferase activity;GO:0031624//ubiquitin conjugating enzyme binding","GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0000209//protein polyubiquitination","K12009//tripartite motif-containing protein 27 [EC:2.3.2.27];K19720//collagen, type III, alpha","NP_001316905.1//LON peptidase N-terminal domain and RING finger protein 1 isoform 2 [Homo sapiens];NP_689484.3//LON peptidase N-terminal domain and RING finger protein 1 isoform 1 [Homo sapiens]","4;1//3"]
[7439,2421,0.22,0.46,1.06413033741972,0.176921640537944,"*",0.0922376,"BEST1","GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0034707//chloride channel complex;GO:0005886//plasma membrane","GO:0005229//intracellular calcium activated chloride channel activity;GO:0042802//identical protein binding;GO:0005254//chloride channel activity;GO:0015106//bicarbonate transmembrane transporter activity","GO:0030321//transepithelial chloride transport;GO:0051924//regulation of calcium ion transport;GO:0050908//detection of light stimulus involved in visual perception;GO:0006821//chloride transport;GO:0034220//ion transmembrane transport;GO:0007601//visual perception","K13878//bestrophin-1","XP_011543532.1//PREDICTED: bestrophin-1 isoform X2 [Homo sapiens];XP_018891909.1//PREDICTED: bestrophin-1 isoform X2 [Gorilla gorilla gorilla];XP_012367626.1//PREDICTED: bestrophin-1 [Nomascus leucogenys]","1//3;3//A2MP1"]
[7130,1439,0.11,0.23,1.06413033741972,0.608526787479963,"*",0.451538,"TNFAIP6","GO:1904724//tertiary granule lumen;GO:0005615//extracellular space;GO:1904813//ficolin-1-rich granule lumen;GO:0005576//extracellular region","GO:0005540//hyaluronic acid binding","GO:0007165//signal transduction;GO:0030335//positive regulation of cell migration;GO:0007267//cell-cell signaling;GO:0030728//ovulation;GO:0050728//negative regulation of inflammatory response;GO:0006954//inflammatory response;GO:0007155//cell adhesion;GO:0043312//neutrophil degranulation","K19018//tumor necrosis factor-inducible gene 6 protein","NP_009046.2//tumor necrosis factor-inducible gene 6 protein precursor [Homo sapiens]","3//A2MP1"]
[6850,5022,0.11,0.23,1.06413033741972,0.23681231799687,"*",0.1326232,"SYK","GO:0042101//T cell receptor complex;GO:0005634//nucleus;GO:0019815//B cell receptor complex;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0005829//cytosol;GO:0032009//early phagosome;GO:0005737//cytoplasm","GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005524//ATP binding;GO:0005102//receptor binding;GO:0004716//signal transducer, downstream of receptor, with protein tyrosine kinase activity;GO:0042169//SH2 domain binding;GO:0019901//protein kinase binding;GO:0035325//Toll-like receptor binding;GO:0004674//protein serine/threonine kinase activity;GO:0005178//integrin binding;GO:0001784//phosphotyrosine residue binding;GO:0019902//phosphatase binding","GO:0050850//positive regulation of calcium-mediated signaling;GO:0016477//cell migration;GO:0032481//positive regulation of type I interferon production;GO:0007159//leukocyte cell-cell adhesion;GO:0090237//regulation of arachidonic acid secretion;GO:0031623//receptor internalization;GO:0002283//neutrophil activation involved in immune response;GO:0002092//positive regulation of receptor internalization;GO:0019370//leukotriene biosynthetic process;GO:0010803//regulation of tumor necrosis factor-mediated signaling pathway;GO:0002554//serotonin secretion by platelet;GO:0090330//regulation of platelet aggregation;GO:0045087//innate immune response;GO:0030154//cell differentiation;GO:0001525//angiogenesis;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0045579//positive regulation of B cell differentiation;GO:0046777//protein autophosphorylation;GO:0007257//activation of JUN kinase activity;GO:0002250//adaptive immune response;GO:0018105//peptidyl-serine phosphorylation;GO:0048514//blood vessel morphogenesis;GO:0050764//regulation of phagocytosis;GO:0032928//regulation of superoxide anion generation;GO:1900086//positive regulation of peptidyl-tyrosine autophosphorylation;GO:0071404//cellular response to low-density lipoprotein particle stimulus;GO:0038083//peptidyl-tyrosine autophosphorylation;GO:0046641//positive regulation of alpha-beta T cell proliferation;GO:0035556//intracellular signal transduction;GO:0042742//defense response to bacterium;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0045401//positive regulation of interleukin-3 biosynthetic process;GO:0071226//cellular response to molecule of fungal origin;GO:0045425//positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process;GO:0007229//integrin-mediated signaling pathway;GO:0043366//beta selection;GO:0002281//macrophage activation involved in immune response;GO:0050853//B cell receptor signaling pathway;GO:0030593//neutrophil chemotaxis;GO:0001945//lymph vessel development;GO:0043306//positive regulation of mast cell degranulation;GO:0051090//regulation of DNA binding transcription factor activity;GO:0046638//positive regulation of alpha-beta T cell differentiation;GO:0042991//transcription factor import into nucleus;GO:0006954//inflammatory response;GO:0045780//positive regulation of bone resorption;GO:0038063//collagen-activated tyrosine kinase receptor signaling pathway;GO:0009887//animal organ morphogenesis;GO:0045588//positive regulation of gamma-delta T cell differentiation;GO:0043313//regulation of neutrophil degranulation;GO:0050715//positive regulation of cytokine secretion;GO:0033630//positive regulation of cell adhesion mediated by integrin","K05855//spleen tyrosine kinase [EC:2.7.10.2]","NP_001128524.1//tyrosine-protein kinase SYK isoform Syk(S) [Homo sapiens];NP_003168.2//tyrosine-protein kinase SYK isoform Syk(L) [Homo sapiens]","6;3//A2MP1;2//1"]
[375307,1414,0.11,0.23,1.06413033741972,0.60837280802969,"*",0.451538,"CATIP","GO:0005634//nucleus;GO:0015629//actin cytoskeleton;GO:0005886//plasma membrane;GO:0005737//cytoplasm","NA","GO:0044782//cilium organization;GO:0030041//actin filament polymerization","K12347//natural resistance-associated macrophage protein 1;K09291//nucleoprotein TPR","NP_001307794.1//ciliogenesis-associated TTC17-interacting protein isoform 1 [Homo sapiens];NP_940961.1//ciliogenesis-associated TTC17-interacting protein isoform 2 [Homo sapiens]","1//3"]
[729978,1412,0.24,0.5,1.05889368905357,0.407494420921065,"*",0.265328,"NPIPB2","GO:0005654//nucleoplasm;GO:0016021//integral component of membrane","NA","NA","K04574//neurofilament heavy polypeptide;K13171//serine/arginine repetitive matrix protein 1","AHY28916.1//nuclear pore complex-interacting protein B type [Homo sapiens]","1//3"]
[8509,4004,6.89,14.35,1.05847484885876,{"v":7.59048175454545e-30,"d":"7.59E-30"},"Up",{"v":2.09078e-31,"d":"2.09E-31"},"NDST2","GO:0016021//integral component of membrane","GO:0016787//hydrolase activity;GO:0015016//[heparan sulfate]-glucosamine N-sulfotransferase activity","NA","K02577//heparan sulfate N-deacetylase/N-sulfotransferase NDST2 [EC:3.1.1.- 2.8.2.-]","XP_015107197.1//PREDICTED: bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 isoform X2 [Vicugna pacos];XP_003409114.1//PREDICTED: bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 isoform X1 [Loxodonta africana]","1//3;3//A2MP1"]
[60484,1795,0.13,0.27,1.05444778402238,0.496027564751792,"*",0.342164,"HAPLN2","GO:0005578//proteinaceous extracellular matrix","GO:0005201//extracellular matrix structural constituent;GO:0005540//hyaluronic acid binding","GO:0007155//cell adhesion;GO:0008065//establishment of blood-nerve barrier;GO:0085029//extracellular matrix assembly;GO:0001501//skeletal system development;GO:0007417//central nervous system development","K06851//hyaluronan and proteoglycan link protein 2","NP_068589.1//hyaluronan and proteoglycan link protein 2 precursor [Homo sapiens]","2//1"]
[3293,1134,0.14,0.29,1.05062607306997,0.608321498861432,"*",0.451538,"HSD17B3","GO:0043231//intracellular membrane-bounded organelle;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0047035//testosterone dehydrogenase (NAD+) activity;GO:0047045//testosterone 17-beta-dehydrogenase (NADP+) activity","GO:0061370//testosterone biosynthetic process;GO:0030539//male genitalia development;GO:0006702//androgen biosynthetic process","K10207//testosterone 17beta-dehydrogenase (NADP+) [EC:1.1.1.64]","NP_000188.1//testosterone 17-beta-dehydrogenase 3 [Homo sapiens]","1//3"]
[100130311,3099,0.15,0.31,1.04730571477836,0.285806842482461,"*",0.1657694,"C17orf107","NA","NA","NA","K04817//nicotinic acetylcholine receptor epsilon","XP_011813756.1//PREDICTED: uncharacterized protein C17orf107 homolog isoform X2 [Colobus angolensis palliatus]","1//3"]
[10878,1484,0.61,1.26,1.04654258593703,0.0879907337878375,"*",0.0403984,"CFHR3","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0072562//blood microparticle","NA","NA","K04004//complement factor H","NP_066303.2//complement factor H-related protein 3 isoform 1 precursor [Homo sapiens];NP_001160096.1//complement factor H-related protein 3 isoform 2 precursor [Homo sapiens]","1//3;5"]
[53833,2171,0.18,0.37,1.03952836418664,0.34457280124031,"*",0.208698,"IL20RB","GO:0016021//integral component of membrane","GO:0042015//interleukin-20 binding","GO:0032733//positive regulation of interleukin-10 production;GO:0048873//homeostasis of number of cells within a tissue;GO:0002765//immune response-inhibiting signal transduction;GO:0001808//negative regulation of type IV hypersensitivity;GO:0032703//negative regulation of interleukin-2 production;GO:0042130//negative regulation of T cell proliferation;GO:0032753//positive regulation of interleukin-4 production;GO:0002437//inflammatory response to antigenic stimulus;GO:0032689//negative regulation of interferon-gamma production","K05137//interleukin 20 receptor beta","XP_010363116.1//PREDICTED: interleukin-20 receptor subunit beta [Rhinopithecus roxellana]","3//A2MP1"]
[10859,2782,0.37,0.76,1.03847414781464,0.0544282325934579,"*",0.0233332,"LILRB1","NA","NA","NA","K06512//leukocyte immunoglobulin-like receptor","XP_016881677.1//PREDICTED: leukocyte immunoglobulin-like receptor subfamily B member 1 isoform X8 [Homo sapiens];XP_016881679.1//PREDICTED: leukocyte immunoglobulin-like receptor subfamily B member 1 isoform X10 [Homo sapiens];XP_016881681.1//PREDICTED: leukocyte immunoglobulin-like receptor subfamily B member 1 isoform X14 [Homo sapiens];XP_016881678.1//PREDICTED: leukocyte immunoglobulin-like receptor subfamily B member 1 isoform X9 [Homo sapiens]","6;3//A2MP1;2//1"]
[8348,467,0.2,0.41,1.03562390973072,0.732286116159388,"*",0.623548,"HIST1H2BO","GO:0005634//nucleus;GO:0000786//nucleosome","GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity","NA","K11252//histone H2B","XP_003502246.1//PREDICTED: histone H2B type 1 isoform X1 [Cricetulus griseus]",4]
[1506,1197,2.8,5.73,1.03310831181194,0.000408118475793555,"Up",0.0001054404,"CTRL","GO:0005615//extracellular space","GO:0004252//serine-type endopeptidase activity","GO:0006508//proteolysis;GO:0007586//digestion","K09632//chymotrypsin-like protease [EC:3.4.21.-]","AAH39716.1//CTRL protein, partial [Homo sapiens]","2//1"]
[348013,1204,0.47,0.96,1.03037364904352,0.12884824,"*",0.0632384,"TMEM255B","GO:0016021//integral component of membrane","NA","NA","NA","NP_872420.1//transmembrane protein 255B isoform 1 [Homo sapiens];NP_001335592.1//transmembrane protein 255B isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[4582,1828,8.64,17.63,1.02892925715671,{"v":4.29868747368421e-16,"d":"4.30E-16"},"Up",{"v":2.76102e-17,"d":"2.76E-17"},"MUC1","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0016324//apical plasma membrane;GO:0005737//cytoplasm;GO:0031982//vesicle;GO:0000790//nuclear chromatin;GO:0005796//Golgi lumen;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0002039//p53 binding;GO:0003712//transcription cofactor activity","GO:0010944//negative regulation of transcription by competitive promoter binding;GO:0007565//female pregnancy;GO:0033629//negative regulation of cell adhesion mediated by integrin;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0001701//in utero embryonic development;GO:0036003//positive regulation of transcription from RNA polymerase II promoter in response to stress;GO:0001666//response to hypoxia;GO:0016266//O-glycan processing;GO:0071300//cellular response to retinoic acid;GO:1902166//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0043618//regulation of transcription from RNA polymerase II promoter in response to stress;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0090240//positive regulation of histone H4 acetylation;GO:0030855//epithelial cell differentiation;GO:0006978//DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator","K06568//mucin-1","NP_001018017.1//mucin-1 isoform 3 precursor [Homo sapiens];NP_001018016.1//mucin-1 isoform 2 precursor [Homo sapiens];NP_001191217.1//mucin-1 isoform 12 precursor [Homo sapiens];NP_001191220.1//mucin-1 isoform 15 precursor [Homo sapiens];NP_001037857.1//mucin-1 isoform 7 precursor [Homo sapiens];NP_001191214.1//mucin-1 isoform 9 precursor [Homo sapiens];NP_001191223.1//mucin-1 isoform 18 precursor [Homo sapiens];NP_001037856.1//mucin-1 isoform 6 precursor [Homo sapiens];NP_001191216.1//mucin-1 isoform 11 precursor [Homo sapiens];NP_001191222.1//mucin-1 isoform 17 precursor [Homo sapiens];NP_002447.4//mucin-1 isoform 1 precursor [Homo sapiens];NP_001191221.1//mucin-1 isoform 16 precursor [Homo sapiens];NP_001191215.1//mucin-1 isoform 10 precursor [Homo sapiens];NP_001037855.1//mucin-1 isoform 5 precursor [Homo sapiens];NP_001191224.1//mucin-1 isoform 19 precursor [Homo sapiens];NP_001191225.1//mucin-1 isoform 20 precursor [Homo sapiens];NP_001037858.1//mucin-1 isoform 8 precursor [Homo sapiens];NP_001191226.1//mucin-1 isoform 21 precursor [Homo sapiens];NP_001191219.1//mucin-1 isoform 14 precursor [Homo sapiens];NP_001191218.1//mucin-1 isoform 13 precursor [Homo sapiens]","1//3;2//1;5"]
[7004,1776,29.76,60.72,1.02879726430743,{"v":1.03116107776744E-51,"d":"1.03E-51"},"Up",{"v":1.387878e-53,"d":"1.39E-53"},"TEAD4","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription factor complex","GO:0043565//sequence-specific DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0001085//RNA polymerase II transcription factor binding","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0035329//hippo signaling;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007517//muscle organ development;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0001501//skeletal system development;GO:0048568//embryonic organ development","K09448//transcriptional enhancer factor","XP_008972017.1//PREDICTED: transcriptional enhancer factor TEF-3 isoform X2 [Pan paniscus];NP_003204.2//transcriptional enhancer factor TEF-3 isoform 1 [Homo sapiens];XP_014697124.1//PREDICTED: transcriptional enhancer factor TEF-3, partial [Equus asinus]","3//A2MP1;2//1"]
[100133093,335,0.27,0.55,1.02647221136119,0.733040605828672,"*",0.623548,"FAM25G","NA","NA","NA","NA","CAI12205.1//family with sequence similarity 25, member B, partial [Homo sapiens]","1//3"]
[1942,1584,7.54,15.35,1.02560222698888,{"v":2.40027317851959e-12,"d":"2.40E-12"},"Up",{"v":2.0706E-13,"d":"2.07E-13"},"EFNA1","GO:0070062//extracellular exosome;GO:0005887//integral component of plasma membrane;GO:0046658//anchored component of plasma membrane;GO:0005886//plasma membrane","GO:0046875//ephrin receptor binding;GO:0005102//receptor binding","GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0016477//cell migration;GO:0050730//regulation of peptidyl-tyrosine phosphorylation;GO:1903051//negative regulation of proteolysis involved in cellular protein catabolic process;GO:0014028//notochord formation;GO:0033628//regulation of cell adhesion mediated by integrin;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0001934//positive regulation of protein phosphorylation;GO:1902004//positive regulation of amyloid-beta formation;GO:0003199//endocardial cushion to mesenchymal transition involved in heart valve formation;GO:0050770//regulation of axonogenesis;GO:0007411//axon guidance;GO:0030182//neuron differentiation;GO:1902961//positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process;GO:0034446//substrate adhesion-dependent cell spreading;GO:0043535//regulation of blood vessel endothelial cell migration;GO:0001525//angiogenesis;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0007267//cell-cell signaling;GO:0048013//ephrin receptor signaling pathway;GO:0043409//negative regulation of MAPK cascade;GO:0045765//regulation of angiogenesis;GO:0003183//mitral valve morphogenesis;GO:0003180//aortic valve morphogenesis;GO:0070244//negative regulation of thymocyte apoptotic process;GO:0043410//positive regulation of MAPK cascade;GO:0050821//protein stabilization;GO:0061002//negative regulation of dendritic spine morphogenesis","K05462//ephrin-A","NP_004419.2//ephrin-A1 isoform a precursor [Homo sapiens];NP_872626.1//ephrin-A1 isoform b precursor [Homo sapiens]","1//3;2//1"]
[283991,1604,36.03,73.28,1.02422085167015,{"v":2.63947054583333e-56,"d":"2.64E-56"},"Up",{"v":3.17252e-58,"d":"3.17E-58"},"UBALD2","NA","NA","NA","K16628//collagen, type VII, alpha","NP_872371.1//UBA-like domain-containing protein 2 [Homo sapiens]","3//A2MP1"]
[170067,5179,0.31,0.63,1.02308361311304,0.0187701886665546,"*",0.006988,"SUPT20HL2","NA","NA","NA","K21245//transcription factor SPT20 homolog","NP_001129705.2//putative transcription factor SPT20 homolog-like 2 precursor [Homo sapiens]","2//1"]
[353376,3203,0.66,1.34,1.02169507109932,0.00507033007163601,"*",0.00163943,"TICAM2","GO:0010008//endosome membrane;GO:0030667//secretory granule membrane;GO:0005783//endoplasmic reticulum;GO:0005770//late endosome;GO:0031902//late endosome membrane;GO:0005768//endosome;GO:0031901//early endosome membrane;GO:0005794//Golgi apparatus;GO:0005769//early endosome;GO:0005886//plasma membrane","GO:0004871//signal transducer activity;GO:0005543//phospholipid binding","GO:0070671//response to interleukin-12;GO:0032755//positive regulation of interleukin-6 production;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0097190//apoptotic signaling pathway;GO:0071650//negative regulation of chemokine (C-C motif) ligand 5 production;GO:0071222//cellular response to lipopolysaccharide;GO:0035669//TRAM-dependent toll-like receptor 4 signaling pathway;GO:0043312//neutrophil degranulation;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0045087//innate immune response;GO:0032729//positive regulation of interferon-gamma production;GO:0034142//toll-like receptor 4 signaling pathway;GO:0007165//signal transduction;GO:0071651//positive regulation of chemokine (C-C motif) ligand 5 production;GO:0051607//defense response to virus;GO:0034144//negative regulation of toll-like receptor 4 signaling pathway;GO:0006954//inflammatory response;GO:0034128//negative regulation of MyD88-independent toll-like receptor signaling pathway;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0070266//necroptotic process;GO:2000494//positive regulation of interleukin-18-mediated signaling pathway;GO:0034145//positive regulation of toll-like receptor 4 signaling pathway","K05409//TRIF-related adaptor molecule","NP_067681.1//TIR domain-containing adapter molecule 2 [Homo sapiens]",7]
[50649,3722,0.35,0.71,1.02046410255972,0.0551359292298716,"*",0.0236642,"ARHGEF4","NA","NA","NA","K05769//Rho guanine nucleotide exchange factor 4/29","XP_005263738.1//PREDICTED: rho guanine nucleotide exchange factor 4 isoform X1 [Homo sapiens]","3//A2MP1;2//1"]
[283518,1639,0.4,0.81,1.01792190799726,0.199852946763602,"*",0.106695,"KCNRG","GO:0005783//endoplasmic reticulum","GO:0042802//identical protein binding","GO:1902260//negative regulation of delayed rectifier potassium channel activity;GO:0051260//protein homooligomerization","K21916//BTB/POZ domain-containing protein KCTD6","NP_775876.1//potassium channel regulatory protein isoform 1 [Homo sapiens];NP_955751.1//potassium channel regulatory protein isoform 2 [Homo sapiens]","1//3;2//1"]
[7755,2065,7.28,14.74,1.01772616889637,{"v":5.42021695729537E-15,"d":"5.42E-15"},"Up",{"v":3.8139e-16,"d":"3.81E-16"},"ZNF205","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_006163049.2//PREDICTED: zinc finger protein 205 isoform X2 [Tupaia chinensis]","1//3;2//1"]
[54897,4875,0.52,1.05,1.01380579952503,0.0097513375872093,"*",0.00335992,"CASZ1","NA","NA","NA","K10955//mucin-2","XP_007978782.1//PREDICTED: zinc finger protein castor homolog 1 isoform X1 [Chlorocebus sabaeus];XP_011539937.1//PREDICTED: zinc finger protein castor homolog 1 isoform X4 [Homo sapiens]","4;2//1"]
[8061,1591,118.05,237.95,1.01126041293185,{"v":5.09546081767442e-164,"d":"5.10E-164"},"Up",{"v":1.371634e-166,"d":"1.37E-166"},"FOSL1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0042734//presynaptic membrane;GO:0043005//neuron projection","GO:0003677//DNA binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0034097//response to cytokine;GO:0032570//response to progesterone;GO:0007296//vitellogenesis;GO:0009629//response to gravity;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0061614//pri-miRNA transcription from RNA polymerase II promoter;GO:0043065//positive regulation of apoptotic process;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0006935//chemotaxis;GO:0031668//cellular response to extracellular stimulus;GO:0008285//negative regulation of cell proliferation;GO:0060674//placenta blood vessel development;GO:0009612//response to mechanical stimulus;GO:0042493//response to drug;GO:0007565//female pregnancy;GO:0051591//response to cAMP;GO:0001701//in utero embryonic development;GO:0007612//learning;GO:2000144//positive regulation of DNA-templated transcription, initiation;GO:0042542//response to hydrogen peroxide;GO:0006968//cellular defense response;GO:0006366//transcription from RNA polymerase II promoter;GO:0009615//response to virus;GO:0045787//positive regulation of cell cycle;GO:0008284//positive regulation of cell proliferation;GO:0051412//response to corticosterone","K04502//fos-like antigen 1","NP_001287786.1//fos-related antigen 1 isoform 5 [Homo sapiens];NP_001287785.1//fos-related antigen 1 isoform 4 [Homo sapiens];NP_005429.1//fos-related antigen 1 isoform 1 [Homo sapiens];XP_021569600.1//fos-related antigen 1 isoform X3 [Carlito syrichta];NP_001287773.1//fos-related antigen 1 isoform 2 [Homo sapiens]","4;1//3"]
[170302,2885,0.66,1.33,1.01088831614274,0.012666432437566,"*",0.00450866,"ARX","NA","NA","NA","K09452//homeobox protein aristaless-related","XP_021520387.1//homeobox protein ARX [Meriones unguiculatus]","2//1"]
[2921,1166,6.09,12.21,1.00354906708107,{"v":2.31216208695652E-7,"d":"2.31E-07"},"Up",{"v":3.4956e-08,"d":"3.50E-08"},"CXCL3","GO:0005615//extracellular space;GO:0005576//extracellular region","GO:0045236//CXCR chemokine receptor binding;GO:0008009//chemokine activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0090023//positive regulation of neutrophil chemotaxis;GO:0030593//neutrophil chemotaxis;GO:0042127//regulation of cell proliferation;GO:0070098//chemokine-mediated signaling pathway;GO:0032496//response to lipopolysaccharide;GO:0031640//killing of cells of other organism;GO:0006954//inflammatory response;GO:0006952//defense response;GO:0006955//immune response","K05505//C-X-C motif chemokine 1/2/3","XP_007997073.1//PREDICTED: C-X-C motif chemokine 3 [Chlorocebus sabaeus]","2//1"]
[578,2203,12.91,25.88,1.00334861668532,{"v":6.31593815091278E-27,"d":"6.32E-27"},"Up",{"v":1.949266e-28,"d":"1.95E-28"},"BAK1","GO:0005783//endoplasmic reticulum;GO:0031307//integral component of mitochondrial outer membrane;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0097145//BAK complex;GO:0046930//pore complex;GO:0005741//mitochondrial outer membrane","GO:0044325//ion channel binding;GO:0042802//identical protein binding;GO:0031072//heat shock protein binding;GO:0046982//protein heterodimerization activity;GO:0051400//BH domain binding;GO:0051087//chaperone binding;GO:0042803//protein homodimerization activity","GO:0031100//animal organ regeneration;GO:0019835//cytolysis;GO:0071260//cellular response to mechanical stimulus;GO:0002352//B cell negative selection;GO:0002262//myeloid cell homeostasis;GO:0007420//brain development;GO:0010332//response to gamma radiation;GO:0045471//response to ethanol;GO:0034644//cellular response to UV;GO:0043065//positive regulation of apoptotic process;GO:1900103//positive regulation of endoplasmic reticulum unfolded protein response;GO:0044346//fibroblast apoptotic process;GO:0008285//negative regulation of cell proliferation;GO:0042493//response to drug;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0001783//B cell apoptotic process;GO:0046902//regulation of mitochondrial membrane permeability;GO:0031018//endocrine pancreas development;GO:0032471//negative regulation of endoplasmic reticulum calcium ion concentration;GO:0001974//blood vessel remodeling;GO:0008053//mitochondrial fusion;GO:0048597//post-embryonic camera-type eye morphogenesis;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0010524//positive regulation of calcium ion transport into cytosol;GO:0051726//regulation of cell cycle;GO:0001782//B cell homeostasis;GO:0010248//establishment or maintenance of transmembrane electrochemical gradient;GO:0014070//response to organic cyclic compound;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0009620//response to fungus;GO:0060068//vagina development;GO:0070242//thymocyte apoptotic process;GO:0097202//activation of cysteine-type endopeptidase activity;GO:0010629//negative regulation of gene expression;GO:0043497//regulation of protein heterodimerization activity;GO:0010225//response to UV-C;GO:0008283//cell proliferation;GO:0043496//regulation of protein homodimerization activity;GO:1902262//apoptotic process involved in blood vessel morphogenesis;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0010046//response to mycotoxin;GO:0001836//release of cytochrome c from mitochondria;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0042542//response to hydrogen peroxide;GO:0035108//limb morphogenesis;GO:0007568//aging;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0008635//activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c;GO:0051881//regulation of mitochondrial membrane potential","K14021//Bcl-2 homologous antagonist/killer","NP_001179.1//bcl-2 homologous antagonist/killer [Homo sapiens]","3//A2MP1"]
[54845,3736,0.02,0.04,1,0.736074176174993,"*",0.623548,"ESRP1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body","GO:0003723//RNA binding;GO:0003729//mRNA binding","GO:0043484//regulation of RNA splicing;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0008543//fibroblast growth factor receptor signaling pathway","K14947//epithelial splicing regulatory protein 1/2","AAH19932.1//ESRP1 protein, partial [Homo sapiens];NP_001030087.2//epithelial splicing regulatory protein 1 isoform 2 [Homo sapiens];NP_001116298.1//epithelial splicing regulatory protein 1 isoform 3 [Homo sapiens];NP_060167.2//epithelial splicing regulatory protein 1 isoform 1 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[9423,5954,0.04,0.08,1,0.496252745233339,"*",0.342164,"NTN1","GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005604//basement membrane","NA","GO:0033564//anterior/posterior axon guidance;GO:0045773//positive regulation of axon extension;GO:0098609//cell-cell adhesion;GO:0030334//regulation of cell migration;GO:0042472//inner ear morphogenesis;GO:2000147//positive regulation of cell motility;GO:0030517//negative regulation of axon extension;GO:0007411//axon guidance;GO:0007097//nuclear migration;GO:0032488//Cdc42 protein signal transduction;GO:0006915//apoptotic process;GO:0001764//neuron migration;GO:0060603//mammary gland duct morphogenesis;GO:0007265//Ras protein signal transduction;GO:0008284//positive regulation of cell proliferation;GO:0006930//substrate-dependent cell migration, cell extension","K06843//netrin 1","NP_004813.2//netrin-1 precursor [Homo sapiens]","2//1"]
[326,2299,0.08,0.16,1,0.609400812098682,"*",0.451538,"AIRE","GO:0005634//nucleus;GO:0016604//nuclear body;GO:0005737//cytoplasm","GO:0042393//histone binding;GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0042802//identical protein binding;GO:0044212//transcription regulatory region DNA binding;GO:0003682//chromatin binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0008270//zinc ion binding;GO:0003712//transcription cofactor activity;GO:0045182//translation regulator activity","GO:0097536//thymus epithelium morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0002509//central tolerance induction to self antigen;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045060//negative thymic T cell selection;GO:0032602//chemokine production;GO:0006959//humoral immune response;GO:2000410//regulation of thymocyte migration;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006955//immune response;GO:0002458//peripheral T cell tolerance induction","K10603//autoimmune regulator","NP_000374.1//autoimmune regulator [Homo sapiens]","3//A2MP1"]
[399693,3596,0.01,0.02,1,0.655392351229138,"*",0.499032,"CCDC187","GO:0005813//centrosome","GO:0008017//microtubule binding","GO:0034453//microtubule anchoring","K06237//collagen, type IV, alpha;K16768//centrosomal protein CEP350","AAH31926.1//MGC50722 protein, partial [Homo sapiens]","1//3"]
[144535,9799,0.03,0.06,1,0.5401564,"*",0.385826,"CFAP54","GO:0005737//cytoplasm;GO:0005930//axoneme","NA","GO:0060294//cilium movement involved in cell motility;GO:0060271//cilium assembly;GO:0030154//cell differentiation;GO:0007283//spermatogenesis","K16547//protein NEDD1","NP_001293013.1//cilia- and flagella-associated protein 54 [Homo sapiens]","1//3"]
[4969,3455,0.01,0.02,1,0.654853952846463,"*",0.499032,"OGN","GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0005783//endoplasmic reticulum;GO:0005615//extracellular space;GO:1903561//extracellular vesicle;GO:0005578//proteinaceous extracellular matrix;GO:0005796//Golgi lumen;GO:0005576//extracellular region;GO:0043202//lysosomal lumen","GO:0008083//growth factor activity","GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0018146//keratan sulfate biosynthetic process;GO:0042340//keratan sulfate catabolic process;GO:0007409//axonogenesis","K08126//osteoglycin (osteoinductive factor, mimecan)","NP_077727.3//mimecan isoform 1 [Homo sapiens];XP_012507285.1//PREDICTED: mimecan isoform X2 [Propithecus coquereli]","4;3//A2MP1"]
[400950,3721,0.23,0.46,1,0.105019496172249,"*",0.0494658,"C2orf91","NA","NA","NA","NA","XP_016859586.1//PREDICTED: uncharacterized protein C2orf91 isoform X1 [Homo sapiens]","1//3"]
[84059,19333,0.01,0.02,1,0.03802253,"*",0.0155194,"ADGRV1","NA","NA","NA","K18263//G-protein coupled receptor 98","XP_016865452.1//PREDICTED: G-protein coupled receptor 98 isoform X1 [Homo sapiens]","3//A2MP1"]
[8764,3519,0.01,0.02,1,0.6544776,"*",0.499032,"TNFRSF14","GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0031625//ubiquitin protein ligase binding;GO:0001618//virus receptor activity;GO:0005031//tumor necrosis factor-activated receptor activity","GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0002741//positive regulation of cytokine secretion involved in immune response;GO:0050829//defense response to Gram-negative bacterium;GO:0097190//apoptotic signaling pathway;GO:0042127//regulation of cell proliferation;GO:0032496//response to lipopolysaccharide;GO:0007166//cell surface receptor signaling pathway;GO:0031295//T cell costimulation;GO:0050830//defense response to Gram-positive bacterium;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:2000406//positive regulation of T cell migration;GO:0006954//inflammatory response;GO:0046642//negative regulation of alpha-beta T cell proliferation;GO:0007275//multicellular organism development;GO:0006955//immune response;GO:0042981//regulation of apoptotic process","K05152//tumor necrosis factor receptor superfamily member 14","XP_004024567.1//PREDICTED: tumor necrosis factor receptor superfamily member 14 isoform X1 [Gorilla gorilla gorilla];NP_003811.2//tumor necrosis factor receptor superfamily member 14 isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[285800,2704,0.03,0.06,1,0.735965402098419,"*",0.623548,"PRR18","NA","NA","NA","K16628//collagen, type VII, alpha;K19720//collagen, type III, alpha","NP_787118.2//proline-rich protein 18 [Homo sapiens]","3//A2MP1"]
[100996492,6943,0.02,0.04,1,0.78247950878697,"*",0.685686,"CTXND1","NA","NA","NA","K15696//RING finger protein 113B;K08857//NIMA (never in mitosis gene a)-related kinase 1/4/5 [EC:2.7.11.1];K04460//serine/threonine-protein phosphatase 5 [EC:3.1.3.16]","EAW99119.1//hCG1648316 [Homo sapiens]","1//3"]
[56649,3549,0.01,0.02,1,0.654209041280263,"*",0.499032,"TMPRSS4","GO:0016021//integral component of membrane","GO:0004252//serine-type endopeptidase activity;GO:0005044//scavenger receptor activity","GO:0006508//proteolysis","K09635//transmembrane protease serine 4 [EC:3.4.21.-]","NP_001167023.1//transmembrane protease serine 4 isoform 5 [Homo sapiens];NP_063947.1//transmembrane protease serine 4 isoform 1 [Homo sapiens];NP_001077416.1//transmembrane protease serine 4 isoform 3 [Homo sapiens];NP_001167022.1//transmembrane protease serine 4 isoform 4 [Homo sapiens]","1//3;3//A2MP1"]
[8856,4335,0.01,0.02,1,0.653940702871206,"*",0.499032,"NR1I2","GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0045111//intermediate filament cytoskeleton","GO:0003707//steroid hormone receptor activity;GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0004879//nuclear receptor activity;GO:0003713//transcription coactivator activity;GO:0008144//drug binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0008270//zinc ion binding;GO:0043565//sequence-specific DNA binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0007165//signal transduction;GO:0006805//xenobiotic metabolic process;GO:0006351//transcription, DNA-templated;GO:0010628//positive regulation of gene expression;GO:0045893//positive regulation of transcription, DNA-templated;GO:0008202//steroid metabolic process;GO:0046618//drug export;GO:0042738//exogenous drug catabolic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0042908//xenobiotic transport","K08540//pregnane X receptor","CAB55493.1//nuclear hormone receptor PRR2-C [Homo sapiens];CAB55490.1//nuclear hormone receptor PRR1-C [Homo sapiens];NP_071285.1//nuclear receptor subfamily 1 group I member 2 isoform 2 [Homo sapiens]","3//A2MP1;2//1"]
[2104,5336,0.01,0.02,1,0.653618987208921,"*",0.499032,"ESRRG","GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0003707//steroid hormone receptor activity;GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0050682//AF-2 domain binding;GO:0003708//retinoic acid receptor activity;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0008270//zinc ion binding;GO:0043565//sequence-specific DNA binding;GO:0005496//steroid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated","K08554//estrogen-related receptor gamma","XP_011896067.1//PREDICTED: estrogen-related receptor gamma isoform X4 [Cercocebus atys];XP_013375331.1//PREDICTED: estrogen-related receptor gamma isoform X2 [Chinchilla lanigera];NP_001230447.1//estrogen-related receptor gamma isoform 6 [Homo sapiens];XP_021022013.1//estrogen-related receptor gamma isoform X2 [Mus caroli];XP_004271081.1//PREDICTED: estrogen-related receptor gamma isoform X2 [Orcinus orca];XP_021125556.1//estrogen-related receptor gamma isoform X1 [Anas platyrhynchos];XP_007072888.1//PREDICTED: estrogen-related receptor gamma [Panthera tigris altaica];XP_019598762.1//PREDICTED: estrogen-related receptor gamma isoform X1 [Rhinolophus sinicus];XP_007165028.1//PREDICTED: estrogen-related receptor gamma-like isoform X2 [Balaenoptera acutorostrata scammoni];OXB65319.1//hypothetical protein ASZ78_002511 [Callipepla squamata]","1//3;3//A2MP1;2//1"]
[100130302,5160,0.06,0.12,1,0.36462342052477,"*",0.225316,"SUPT20HL1","NA","NA","NA","K21245//transcription factor SPT20 homolog","NP_001129706.2//transcription factor SPT20 homolog-like 1 precursor [Homo sapiens]","2//1"]
[80258,3269,0.01,0.02,1,0.653511818986719,"*",0.499032,"EFHC2","NA","GO:0005509//calcium ion binding","GO:1990830//cellular response to leukemia inhibitory factor","NA","NP_079460.2//EF-hand domain-containing family member C2 [Homo sapiens]","3//A2MP1"]
[91947,4074,0.08,0.16,1,0.407572792768535,"*",0.265328,"ARRDC4","GO:0005768//endosome;GO:0005886//plasma membrane;GO:1903561//extracellular vesicle;GO:0005769//early endosome","GO:1990756//protein binding, bridging involved in substrate recognition for ubiquitination","GO:0016567//protein ubiquitination;GO:0008104//protein localization;GO:0015031//protein transport;GO:0051443//positive regulation of ubiquitin-protein transferase activity","K20910//thioredoxin-interacting protein","XP_007988715.1//PREDICTED: arrestin domain-containing protein 4 [Chlorocebus sabaeus]","2//1"]
[284612,3779,0.02,0.04,1,0.735693607504247,"*",0.623548,"SYPL2","GO:0008021//synaptic vesicle;GO:0016021//integral component of membrane;GO:0030285//integral component of synaptic vesicle membrane","GO:0005215//transporter activity","GO:0021762//substantia nigra development;GO:0006874//cellular calcium ion homeostasis","K05456//neuregulin 2","XP_011539585.1//PREDICTED: synaptophysin-like protein 2 isoform X1 [Homo sapiens]","1//3"]
[64218,3230,0.01,0.02,1,0.653404685901639,"*",0.499032,"SEMA4A","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","NA","GO:0045063//T-helper 1 cell differentiation;GO:0001525//angiogenesis;GO:0016525//negative regulation of angiogenesis;GO:0050919//negative chemotaxis;GO:0071526//semaphorin-plexin signaling pathway;GO:0010594//regulation of endothelial cell migration;GO:0008360//regulation of cell shape;GO:0007409//axonogenesis","K06521//semaphorin 4","NP_071762.2//semaphorin-4A isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[222611,5135,0.1,0.2,1,0.211480960694847,"*",0.1143194,"ADGRF2","NA","NA","NA","K08454//G protein-coupled receptor 111","XP_012297067.1//adhesion G-protein coupled receptor F2 [Aotus nancymaae]",6]
[54329,4778,0.01,0.02,1,0.653297587936404,"*",0.499032,"GPR85","GO:0005783//endoplasmic reticulum;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005057//signal transducer activity, downstream of receptor;GO:0004930//G-protein coupled receptor activity","GO:0007165//signal transduction","K04302//G protein-coupled receptor 85","NP_071590.1//probable G-protein coupled receptor 85 [Rattus norvegicus]","6;1//3"]
[5079,8771,0.01,0.02,1,0.395108441754316,"*",0.249274,"PAX5","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0001650//fibrillar center","GO:0003677//DNA binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0006355//regulation of transcription, DNA-templated;GO:0021670//lateral ventricle development;GO:0006351//transcription, DNA-templated;GO:0007283//spermatogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0007568//aging;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0035914//skeletal muscle cell differentiation;GO:0009887//animal organ morphogenesis;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0021987//cerebral cortex development;GO:0006959//humoral immune response;GO:0051573//negative regulation of histone H3-K9 methylation;GO:0007275//multicellular organism development;GO:0030534//adult behavior;GO:0050855//regulation of B cell receptor signaling pathway","K09383//paired box protein 5","XP_011794818.1//PREDICTED: paired box protein Pax-5 isoform X5 [Colobus angolensis palliatus];NP_001267483.1//paired box protein Pax-5 isoform 9 [Homo sapiens];NP_001267482.1//paired box protein Pax-5 isoform 8 [Homo sapiens];NP_001267484.1//paired box protein Pax-5 isoform 10 [Homo sapiens];NP_001267479.1//paired box protein Pax-5 isoform 5 [Homo sapiens];NP_001267478.1//paired box protein Pax-5 isoform 4 [Homo sapiens];NP_001267481.1//paired box protein Pax-5 isoform 7 [Homo sapiens];NP_001267476.1//paired box protein Pax-5 isoform 2 [Homo sapiens];NP_001267477.1//paired box protein Pax-5 isoform 3 [Homo sapiens];NP_057953.1//paired box protein Pax-5 isoform 1 [Homo sapiens];XP_010368268.1//PREDICTED: paired box protein Pax-5 isoform X2 [Rhinopithecus roxellana]","1//3;2//1"]
[7852,1691,0.05,0.1,1,0.73563927267356,"*",0.623548,"CXCR4","GO:0070062//extracellular exosome;GO:0031252//cell leading edge;GO:0005770//late endosome;GO:0031410//cytoplasmic vesicle;GO:0030054//cell junction;GO:0005764//lysosome;GO:0005737//cytoplasm;GO:0009986//cell surface;GO:0043234//protein complex;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005769//early endosome","GO:0019955//cytokine binding;GO:0032027//myosin light chain binding;GO:0031625//ubiquitin protein ligase binding;GO:0019957//C-C chemokine binding;GO:0015026//coreceptor activity;GO:0004930//G-protein coupled receptor activity;GO:0016494//C-X-C chemokine receptor activity;GO:0003779//actin binding;GO:0043130//ubiquitin binding;GO:0004950//chemokine receptor activity;GO:0001618//virus receptor activity","GO:0048714//positive regulation of oligodendrocyte differentiation;GO:0002407//dendritic cell chemotaxis;GO:0050920//regulation of chemotaxis;GO:0006935//chemotaxis;GO:0071345//cellular response to cytokine stimulus;GO:0007186//G-protein coupled receptor signaling pathway;GO:0000187//activation of MAPK activity;GO:0030260//entry into host cell;GO:0019722//calcium-mediated signaling;GO:0006915//apoptotic process;GO:0006954//inflammatory response;GO:0001666//response to hypoxia;GO:0019064//fusion of virus membrane with host plasma membrane;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0043217//myelin maintenance;GO:0009615//response to virus","K04189//C-X-C chemokine receptor type 4","NP_003458.1//C-X-C chemokine receptor type 4 isoform b [Homo sapiens];NP_001334988.1//C-X-C chemokine receptor type 4 isoform d [Homo sapiens];NP_001334985.1//C-X-C chemokine receptor type 4 isoform c [Homo sapiens];NP_001008540.1//C-X-C chemokine receptor type 4 isoform a [Homo sapiens]","1//3;2//1"]
[81706,2211,0.18,0.36,1,0.344644045487439,"*",0.208698,"PPP1R14C","GO:0016020//membrane;GO:0005737//cytoplasm","GO:0004865//protein serine/threonine phosphatase inhibitor activity","GO:0042325//regulation of phosphorylation","K17556//protein phosphatase 1 regulatory subunit 14C","XP_008005744.1//PREDICTED: protein phosphatase 1 regulatory subunit 14C isoform X1 [Chlorocebus sabaeus]","2//1"]
[9173,3909,0.02,0.04,1,0.394912513735991,"*",0.249274,"IL1RL1","GO:0009897//external side of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005578//proteinaceous extracellular matrix","GO:0005057//signal transducer activity, downstream of receptor;GO:0002113//interleukin-33 binding;GO:0004896//cytokine receptor activity;GO:0002114//interleukin-33 receptor activity;GO:0004908//interleukin-1 receptor activity","GO:0002826//negative regulation of T-helper 1 type immune response;GO:0007165//signal transduction;GO:0043032//positive regulation of macrophage activation;GO:0090197//positive regulation of chemokine secretion;GO:0050729//positive regulation of inflammatory response;GO:0032754//positive regulation of interleukin-5 production;GO:0006955//immune response;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0032689//negative regulation of interferon-gamma production","K05171//interleukin 1 receptor-like 1","NP_003847.2//interleukin-1 receptor-like 1 isoform 2 precursor [Homo sapiens];NP_057316.3//interleukin-1 receptor-like 1 isoform 1 precursor [Homo sapiens];XP_009234974.1//PREDICTED: interleukin-1 receptor-like 1 isoform X2 [Pongo abelii]","1//3;4;3//A2MP1"]
[6330,4358,0.01,0.02,1,0.652495470901203,"*",0.499032,"SCN4B","GO:0031226//intrinsic component of plasma membrane;GO:0016021//integral component of membrane;GO:0001518//voltage-gated sodium channel complex;GO:0014704//intercalated disc;GO:0005886//plasma membrane","GO:0086006//voltage-gated sodium channel activity involved in cardiac muscle cell action potential;GO:0044325//ion channel binding;GO:0017080//sodium channel regulator activity;GO:0005248//voltage-gated sodium channel activity","GO:0086016//AV node cell action potential;GO:0035725//sodium ion transmembrane transport;GO:0086012//membrane depolarization during cardiac muscle cell action potential;GO:0086091//regulation of heart rate by cardiac conduction;GO:0010765//positive regulation of sodium ion transport;GO:0086002//cardiac muscle cell action potential involved in contraction;GO:2000649//regulation of sodium ion transmembrane transporter activity;GO:0060048//cardiac muscle contraction;GO:0006814//sodium ion transport;GO:0060307//regulation of ventricular cardiac muscle cell membrane repolarization","K04848//voltage-gated sodium channel type IV beta","XP_009245405.1//PREDICTED: sodium channel subunit beta-4 isoform X2 [Pongo abelii];NP_777594.1//sodium channel subunit beta-4 isoform 1 precursor [Homo sapiens];XP_017378896.1//PREDICTED: sodium channel subunit beta-4 [Cebus capucinus imitator]","1//3;3//A2MP1"]
[57111,1138,0.07,0.14,1,0.735422013585351,"*",0.623548,"RAB25","GO:0070062//extracellular exosome;GO:0031410//cytoplasmic vesicle;GO:0031143//pseudopodium;GO:0031260//pseudopodium membrane","GO:0031489//myosin V binding;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0060627//regulation of vesicle-mediated transport;GO:0010634//positive regulation of epithelial cell migration;GO:0031268//pseudopodium organization;GO:0003382//epithelial cell morphogenesis;GO:0015031//protein transport;GO:0008284//positive regulation of cell proliferation","K07906//Ras-related protein Rab-25","AAF98238.1//unknown [Homo sapiens]","3//A2MP1"]
[9229,5214,0.01,0.02,1,0.652228536082474,"*",0.499032,"DLGAP1","GO:0030054//cell junction;GO:0045202//synapse;GO:0014069//postsynaptic density;GO:0005886//plasma membrane;GO:0045211//postsynaptic membrane","GO:0019904//protein domain specific binding","GO:0007268//chemical synaptic transmission;GO:0006461//protein complex assembly","K15008//discs, large-associated protein 1","NP_001229694.1//disks large-associated protein 1 isoform 7 [Homo sapiens];NP_001003809.1//disks large-associated protein 1 isoform 2 [Homo sapiens];XP_012601395.1//disks large-associated protein 1 isoform X9 [Microcebus murinus];NP_001229695.1//disks large-associated protein 1 isoform 8 [Homo sapiens];XP_007972735.1//PREDICTED: disks large-associated protein 1 isoform X3 [Chlorocebus sabaeus];NP_001229693.1//disks large-associated protein 1 isoform 6 [Homo sapiens];NP_001295319.1//disks large-associated protein 1 isoform 9 [Homo sapiens];NP_001229690.1//disks large-associated protein 1 isoform 3 [Homo sapiens];NP_004737.2//disks large-associated protein 1 isoform 1 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[340024,5183,0.01,0.02,1,0.652175175325207,"*",0.499032,"SLC6A19","GO:0070062//extracellular exosome;GO:0005887//integral component of plasma membrane;GO:0031526//brush border membrane;GO:0005886//plasma membrane","GO:0015175//neutral amino acid transmembrane transporter activity;GO:0005328//neurotransmitter:sodium symporter activity;GO:0015171//amino acid transmembrane transporter activity","GO:0006865//amino acid transport;GO:0007584//response to nutrient","K05334//solute carrier family 6 (neurotransmitter transporter) member 19","NP_001003841.1//sodium-dependent neutral amino acid transporter B(0)AT1 [Homo sapiens]","2//1"]
[26683,939,0.01,0.02,1,1.00047252009278,"*",0.999032,"OR4F3","NA","NA","NA","K04257//olfactory receptor","XP_011933019.1//PREDICTED: olfactory receptor 4F3/4F16/4F29 [Cercocebus atys]","1//3"]
[23127,3943,0.01,0.02,1,0.652121823298429,"*",0.499032,"COLGALT2","NA","NA","NA","K11703//collagen beta-1,O-galactosyltransferase [EC:2.4.1.50]","XP_008983098.1//PREDICTED: procollagen galactosyltransferase 2 isoform X2 [Callithrix jacchus];XP_005319757.1//procollagen galactosyltransferase 2 [Ictidomys tridecemlineatus];XP_004372966.2//PREDICTED: procollagen galactosyltransferase 2 [Trichechus manatus latirostris]","1//3;3//A2MP1"]
[255631,6529,0.01,0.02,1,0.394716779936558,"*",0.249274,"COL24A1","GO:0005788//endoplasmic reticulum lumen;GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005578//proteinaceous extracellular matrix","GO:0005201//extracellular matrix structural constituent","GO:0002244//hematopoietic progenitor cell differentiation","K19721//collagen, type V/XI/XXIV/XXVII, alpha","NP_690850.2//collagen alpha-1(XXIV) chain isoform 1 precursor [Homo sapiens]","6;1//3"]
[50944,9615,0.02,0.04,1,0.629145534604905,"*",0.505908,"SHANK1","GO:0016020//membrane;GO:0030425//dendrite;GO:0060076//excitatory synapse;GO:0005622//intracellular;GO:0030054//cell junction;GO:0014069//postsynaptic density;GO:0043005//neuron projection;GO:0017146//NMDA selective glutamate receptor complex;GO:0005829//cytosol;GO:0043197//dendritic spine;GO:0005886//plasma membrane;GO:0045211//postsynaptic membrane","GO:0042802//identical protein binding;GO:0030160//GKAP/Homer scaffold activity;GO:0097110//scaffold protein binding;GO:0031877//somatostatin receptor binding;GO:0008022//protein C-terminus binding;GO:0035255//ionotropic glutamate receptor binding;GO:0071532//ankyrin repeat binding;GO:0017124//SH3 domain binding;GO:0032403//protein complex binding","GO:0050894//determination of affect;GO:0035418//protein localization to synapse;GO:0007016//cytoskeletal anchoring at plasma membrane;GO:0060074//synapse maturation;GO:0046959//habituation;GO:0007616//long-term memory;GO:0060997//dendritic spine morphogenesis;GO:0035176//social behavior;GO:2000311//regulation of AMPA receptor activity;GO:2000463//positive regulation of excitatory postsynaptic potential;GO:0060999//positive regulation of dendritic spine development;GO:0008306//associative learning;GO:0030534//adult behavior;GO:0042048//olfactory behavior;GO:0060013//righting reflex;GO:0032232//negative regulation of actin filament bundle assembly;GO:0050885//neuromuscular process controlling balance;GO:0071625//vocalization behavior;GO:0006461//protein complex assembly","K15009//SH3 and multiple ankyrin repeat domains protein","NP_057232.2//SH3 and multiple ankyrin repeat domains protein 1 [Homo sapiens]",4]
[1837,2153,0.01,0.02,1,0.651855194046938,"*",0.499032,"DTNA","GO:0030424//axon;GO:0030054//cell junction;GO:0005737//cytoplasm;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0043234//protein complex;GO:0042383//sarcolemma;GO:0016021//integral component of membrane;GO:0045202//synapse","GO:0008270//zinc ion binding;GO:0030165//PDZ domain binding","GO:0006941//striated muscle contraction;GO:0007165//signal transduction;GO:0007268//chemical synaptic transmission;GO:0007274//neuromuscular synaptic transmission","K10366//dystrophin","XP_003784795.1//PREDICTED: dystrobrevin alpha isoform X4 [Otolemur garnettii];XP_008953952.1//PREDICTED: dystrobrevin alpha isoform X6 [Pan paniscus];XP_010333749.1//PREDICTED: dystrobrevin alpha isoform X9 [Saimiri boliviensis boliviensis];XP_007521011.1//PREDICTED: dystrobrevin alpha isoform X9 [Erinaceus europaeus];XP_005258278.1//PREDICTED: dystrobrevin alpha isoform X4 [Homo sapiens];XP_007521009.1//PREDICTED: dystrobrevin alpha isoform X8 [Erinaceus europaeus];XP_018869593.1//PREDICTED: dystrobrevin alpha isoform X10 [Gorilla gorilla gorilla];XP_003784794.1//PREDICTED: dystrobrevin alpha isoform X7 [Otolemur garnettii];XP_010333747.1//PREDICTED: dystrobrevin alpha isoform X7 [Saimiri boliviensis boliviensis];EAX01333.1//dystrobrevin, alpha, isoform CRA_l [Homo sapiens];NP_001185874.1//dystrobrevin alpha isoform 17 [Homo sapiens];XP_010333746.1//PREDICTED: dystrobrevin alpha isoform X6 [Saimiri boliviensis boliviensis];XP_003784796.1//PREDICTED: dystrobrevin alpha isoform X6 [Otolemur garnettii];XP_003784793.1//PREDICTED: dystrobrevin alpha isoform X5 [Otolemur garnettii];NP_001381.2//dystrobrevin alpha isoform 1 [Homo sapiens];BAD92339.1//dystrobrevin alpha isoform 2 variant, partial [Homo sapiens]","6;1//3;4;3//A2MP1;5"]
[30062,3197,0.01,0.02,1,0.651748603384842,"*",0.499032,"RAX","GO:0005634//nucleus","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0007389//pattern specification process;GO:0060173//limb development;GO:0043010//camera-type eye development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007601//visual perception;GO:0021854//hypothalamus development","K09332//retina and anterior neural fold homeobox protein","NP_038463.2//retinal homeobox protein Rx [Homo sapiens]","2//1"]
[150365,4006,0.01,0.02,1,0.651482279176201,"*",0.499032,"MEI1","GO:0005623//cell","NA","GO:0045141//meiotic telomere clustering;GO:0007127//meiosis I;GO:0007141//male meiosis I;GO:0007286//spermatid development","NA","NP_689726.3//meiosis inhibitor protein 1 [Homo sapiens]","3//A2MP1"]
[115861,948,0.01,0.02,1,1.00040980240722,"*",0.999032,"NXNL1","GO:0005739//mitochondrion;GO:0005640//nuclear outer membrane;GO:0005737//cytoplasm","GO:0004791//thioredoxin-disulfide reductase activity","GO:0045494//photoreceptor cell maintenance;GO:0045454//cell redox homeostasis","K17609//nucleoredoxin [EC:1.8.1.8]","XP_017356741.1//PREDICTED: nucleoredoxin-like protein 1 [Cebus capucinus imitator]","1//3"]
[342372,5199,0.01,0.02,1,0.651322589100417,"*",0.499032,"PKD1L3","GO:0070062//extracellular exosome;GO:0009986//cell surface;GO:0005886//plasma membrane;GO:0043235//receptor complex;GO:0034703//cation channel complex","GO:0030246//carbohydrate binding;GO:0005262//calcium channel activity","GO:0001581//detection of chemical stimulus involved in sensory perception of sour taste;GO:0001822//kidney development;GO:0050982//detection of mechanical stimulus;GO:0006812//cation transport;GO:0050915//sensory perception of sour taste;GO:0071468//cellular response to acidic pH","K04989//polycystin 1L3","NP_853514.1//polycystic kidney disease protein 1-like 3 precursor [Homo sapiens]","1//3"]
[8785,2001,0.04,0.08,1,0.735204882787127,"*",0.623548,"MATN4","GO:0005576//extracellular region","GO:0005509//calcium ion binding","GO:0030198//extracellular matrix organization","K19467//matrilin-3","NP_003824.2//matrilin-4 isoform 1 precursor [Homo sapiens];NP_085080.1//matrilin-4 isoform 2 precursor [Homo sapiens];NP_085095.1//matrilin-4 isoform 3 precursor [Homo sapiens]","4;3//A2MP1"]
[92086,994,0.01,0.02,1,1.00034709258447,"*",0.999032,"GGTLC1","NA","GO:0036374//glutathione hydrolase activity","GO:0006751//glutathione catabolic process;GO:1901750//leukotriene D4 biosynthetic process","K18592//gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]","XP_016793052.1//PREDICTED: gamma-glutamyltransferase light chain 1 isoform X4 [Pan troglodytes]","2//1"]
[9635,4246,0.01,0.02,1,0.650950283194513,"*",0.499032,"CLCA2","GO:0005634//nucleus;GO:0005887//integral component of plasma membrane;GO:0005576//extracellular region;GO:0030054//cell junction;GO:0005886//plasma membrane;GO:0009925//basal plasma membrane","GO:0015276//ligand-gated ion channel activity;GO:0046872//metal ion binding;GO:0005229//intracellular calcium activated chloride channel activity;GO:0004222//metalloendopeptidase activity;GO:0005254//chloride channel activity","GO:0006810//transport;GO:0007155//cell adhesion;GO:0034220//ion transmembrane transport","K05028//calcium-activated chloride channel regulator 2","NP_006527.1//calcium-activated chloride channel regulator 2 preproprotein [Homo sapiens]",6]
[1589,2041,0.08,0.16,1,0.609246390066729,"*",0.451538,"CYP21A2","GO:0031090//organelle membrane;GO:0005789//endoplasmic reticulum membrane","GO:0008395//steroid hydroxylase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0020037//heme binding;GO:0004509//steroid 21-monooxygenase activity;GO:0005506//iron ion binding;GO:0004497//monooxygenase activity;GO:0005496//steroid binding","GO:0008202//steroid metabolic process;GO:0006694//steroid biosynthetic process;GO:0006704//glucocorticoid biosynthetic process;GO:0006705//mineralocorticoid biosynthetic process;GO:0016125//sterol metabolic process","K00513//steroid 21-monooxygenase [EC:1.14.14.16]","NP_000491.4//steroid 21-hydroxylase isoform a [Homo sapiens];NP_001122062.3//steroid 21-hydroxylase isoform b [Homo sapiens]","3//A2MP1;7"]
[223075,6843,0.01,0.02,1,0.394247809504951,"*",0.249274,"CCDC129","NA","GO:0005102//receptor binding","NA","NA","NP_001244896.1//coiled-coil domain-containing protein 129 isoform 1 [Homo sapiens];NP_001244897.1//coiled-coil domain-containing protein 129 isoform 3 [Homo sapiens]","4;2//1"]
[1296,4397,0.02,0.04,1,0.735150620119566,"*",0.623548,"COL8A2","GO:0031012//extracellular matrix;GO:0005788//endoplasmic reticulum lumen;GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005578//proteinaceous extracellular matrix;GO:0005604//basement membrane","GO:0005201//extracellular matrix structural constituent;GO:0030674//protein binding, bridging","GO:0050673//epithelial cell proliferation;GO:0098609//cell-cell adhesion;GO:0048593//camera-type eye morphogenesis;GO:0001525//angiogenesis;GO:0030198//extracellular matrix organization;GO:0030574//collagen catabolic process","K19479//collagen, type X, alpha","XP_001158595.3//PREDICTED: collagen alpha-2(VIII) chain [Pan troglodytes];AAH96297.1//COL8A2 protein, partial [Homo sapiens]","1//3;3//A2MP1"]
[23026,6892,0.01,0.02,1,0.735096365461255,"*",0.623548,"MYO16","GO:0016020//membrane;GO:0016459//myosin complex;GO:0005829//cytosol","GO:0003779//actin binding;GO:0005524//ATP binding;GO:0003774//motor activity;GO:0032403//protein complex binding","GO:0048812//neuron projection morphogenesis;GO:0014065//phosphatidylinositol 3-kinase signaling","K17481//myosin XVI","NP_001185879.1//unconventional myosin-XVI isoform 1 [Homo sapiens]","2//1"]
[51233,1336,0.12,0.24,1,0.609194933445946,"*",0.451538,"DRICH1","NA","NA","NA","K20030//palmitoyltransferase ZDHHC5/8 [EC:2.3.1.225];K09341//homeobox protein MSX","NP_057533.2//aspartate-rich protein 1 [Homo sapiens]","3//A2MP1"]
[83481,16018,0.01,0.02,1,0.811123600196257,"*",0.724446,"EPPK1","GO:0005856//cytoskeleton;GO:0016323//basolateral plasma membrane;GO:0042995//cell projection;GO:0016327//apicolateral plasma membrane;GO:0045111//intermediate filament cytoskeleton;GO:0071944//cell periphery;GO:0097356//perinucleolar compartment;GO:0005737//cytoplasm;GO:0030056//hemidesmosome;GO:0005923//bicellular tight junction;GO:0045095//keratin filament","GO:0003723//RNA binding;GO:0008092//cytoskeletal protein binding;GO:0019215//intermediate filament binding","GO:0010839//negative regulation of keratinocyte proliferation;GO:0045109//intermediate filament organization;GO:1905041//regulation of epithelium regeneration;GO:0042060//wound healing;GO:0030336//negative regulation of cell migration;GO:0051548//negative regulation of keratinocyte migration;GO:0050680//negative regulation of epithelial cell proliferation;GO:0061045//negative regulation of wound healing","K10388//plectin","XP_016869378.1//PREDICTED: epiplakin isoform X1 [Homo sapiens]","3//A2MP1"]
[83401,1455,0.11,0.22,1,0.609143485516426,"*",0.451538,"ELOVL3","GO:0005783//endoplasmic reticulum;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0009922//fatty acid elongase activity;GO:0102336//3-oxo-arachidoyl-CoA synthase activity;GO:0102756//very-long-chain 3-ketoacyl-CoA synthase activity;GO:0102337//3-oxo-cerotoyl-CoA synthase activity;GO:0102338//3-oxo-lignoceronyl-CoA synthase activity","GO:0030148//sphingolipid biosynthetic process;GO:0043651//linoleic acid metabolic process;GO:0019367//fatty acid elongation, saturated fatty acid;GO:0036109//alpha-linolenic acid metabolic process;GO:0006636//unsaturated fatty acid biosynthetic process;GO:0034626//fatty acid elongation, polyunsaturated fatty acid;GO:0035338//long-chain fatty-acyl-CoA biosynthetic process;GO:0034625//fatty acid elongation, monounsaturated fatty acid;GO:0042761//very long-chain fatty acid biosynthetic process","K10248//elongation of very long chain fatty acids protein 3 [EC:2.3.1.199]","NP_689523.1//elongation of very long chain fatty acids protein 3 [Homo sapiens]","2//1"]
[220296,3563,0.01,0.02,1,0.650313033773862,"*",0.499032,"HEPACAM","GO:0030424//axon;GO:0005911//cell-cell junction;GO:0016021//integral component of membrane","NA","GO:0034613//cellular protein localization","K06499//carcinoembryonic antigen-related cell adhesion molecule","XP_017379421.1//PREDICTED: hepatocyte cell adhesion molecule isoform X1 [Cebus capucinus imitator]",4]
[1013,2875,0.03,0.06,1,0.73504211881042,"*",0.623548,"CDH15","GO:0070062//extracellular exosome;GO:0005901//caveola;GO:0031594//neuromuscular junction;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005509//calcium ion binding","GO:0051149//positive regulation of muscle cell differentiation;GO:0007155//cell adhesion;GO:0034332//adherens junction organization;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules","K06809//cadherin 15, M-cadherin","NP_004924.1//cadherin-15 preproprotein [Homo sapiens]","2//1"]
[4435,1043,0.5,1,1,0.251460150464396,"*",0.1423692,"CITED1","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0001105//RNA polymerase II transcription coactivator activity;GO:0044212//transcription regulatory region DNA binding;GO:0042803//protein homodimerization activity;GO:0050693//LBD domain binding;GO:0070410//co-SMAD binding;GO:0008022//protein C-terminus binding;GO:0003713//transcription coactivator activity;GO:0003682//chromatin binding;GO:0003700//DNA binding transcription factor activity","GO:0001890//placenta development;GO:0043627//response to estrogen;GO:0007420//brain development;GO:0060711//labyrinthine layer development;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0060712//spongiotrophoblast layer development;GO:0070555//response to interleukin-1;GO:0045668//negative regulation of osteoblast differentiation;GO:0001570//vasculogenesis;GO:0000578//embryonic axis specification;GO:0045892//negative regulation of transcription, DNA-templated;GO:0071105//response to interleukin-11;GO:0071104//response to interleukin-9;GO:0043524//negative regulation of neuron apoptotic process;GO:0010628//positive regulation of gene expression;GO:0006915//apoptotic process;GO:0070670//response to interleukin-4;GO:0030178//negative regulation of Wnt signaling pathway;GO:0034097//response to cytokine;GO:0032496//response to lipopolysaccharide;GO:0070669//response to interleukin-2;GO:0045893//positive regulation of transcription, DNA-templated;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0042438//melanin biosynthetic process;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0034341//response to interferon-gamma;GO:0071559//response to transforming growth factor beta;GO:0030318//melanocyte differentiation;GO:0001656//metanephros development;GO:0071107//response to parathyroid hormone;GO:0032868//response to insulin;GO:0051591//response to cAMP;GO:0070741//response to interleukin-6;GO:0060395//SMAD protein signal transduction;GO:0043473//pigmentation;GO:0006913//nucleocytoplasmic transport;GO:0060231//mesenchymal to epithelial transition;GO:0003340//negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0042981//regulation of apoptotic process","K21361//Cbp/p300-interacting transactivator 2","XP_005657879.1//cbp/p300-interacting transactivator 1 isoform X1 [Sus scrofa];XP_003917925.2//cbp/p300-interacting transactivator 1 isoform X1 [Papio anubis];NP_001138357.1//cbp/p300-interacting transactivator 1 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[388015,4193,0.01,0.02,1,0.649729983535741,"*",0.499032,"RTL1","GO:0016021//integral component of membrane","NA","GO:0007275//multicellular organism development","K04612//calcium-sensing receptor;K21125//mucin-5AC;K17599//transmembrane protein 132","NP_001128360.1//retrotransposon-like protein 1 [Homo sapiens]","2//1"]
[1128,2863,0.03,0.06,1,0.734879426885052,"*",0.623548,"CHRM1","GO:0016020//membrane;GO:0030425//dendrite;GO:0030054//cell junction;GO:0014069//postsynaptic density;GO:0005887//integral component of plasma membrane;GO:0043679//axon terminus;GO:0005886//plasma membrane;GO:0045202//synapse;GO:0045211//postsynaptic membrane","GO:0016907//G-protein coupled acetylcholine receptor activity;GO:0004435//phosphatidylinositol phospholipase C activity;GO:0008144//drug binding","GO:0007399//nervous system development;GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0046541//saliva secretion;GO:0090316//positive regulation of intracellular protein transport;GO:0007274//neuromuscular synaptic transmission;GO:0008283//cell proliferation;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007197//adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway;GO:0007213//G-protein coupled acetylcholine receptor signaling pathway;GO:0043270//positive regulation of ion transport;GO:0007165//signal transduction;GO:0003056//regulation of vascular smooth muscle contraction;GO:0009649//entrainment of circadian clock;GO:0007207//phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway;GO:0050890//cognition;GO:0007271//synaptic transmission, cholinergic;GO:0007603//phototransduction, visible light;GO:0006464//cellular protein modification process;GO:0040012//regulation of locomotion;GO:0008284//positive regulation of cell proliferation","K04129//muscarinic acetylcholine receptor M1","OBS58793.1//hypothetical protein A6R68_10121 [Neotoma lepida]","2//1"]
[50506,6428,0.01,0.02,1,0.3938578512364,"*",0.249274,"DUOX2","GO:0070062//extracellular exosome;GO:0016324//apical plasma membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0005886//plasma membrane","GO:0016174//NAD(P)H oxidase activity;GO:0020037//heme binding;GO:0004601//peroxidase activity;GO:0005509//calcium ion binding","GO:0042446//hormone biosynthetic process;GO:0042335//cuticle development;GO:0055114//oxidation-reduction process;GO:0030878//thyroid gland development;GO:0048839//inner ear development;GO:0048855//adenohypophysis morphogenesis;GO:0030282//bone mineralization;GO:0009566//fertilization;GO:0051591//response to cAMP;GO:0035264//multicellular organism growth;GO:0006979//response to oxidative stress;GO:0006590//thyroid hormone generation;GO:0042744//hydrogen peroxide catabolic process;GO:0019221//cytokine-mediated signaling pathway;GO:0050665//hydrogen peroxide biosynthetic process;GO:0009615//response to virus","K13411//dual oxidase [EC:1.6.3.1 1.11.1.-]","NP_054799.4//dual oxidase 2 precursor [Homo sapiens]",4]
[3841,2172,0.26,0.52,1,0.236891758559767,"*",0.1326232,"KPNA5","GO:0005634//nucleus;GO:0005829//cytosol","GO:0008565//protein transporter activity","GO:0006606//protein import into nucleus","K15042//importin subunit alpha-1","XP_002817323.1//PREDICTED: LOW QUALITY PROTEIN: importin subunit alpha-6 [Pongo abelii]","2//1"]
[5657,1001,0.33,0.66,1,0.407533603076923,"*",0.265328,"PRTN3","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0035578//azurophil granule lumen;GO:0005829//cytosol;GO:0044853//plasma membrane raft;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0004252//serine-type endopeptidase activity;GO:0005102//receptor binding;GO:0019899//enzyme binding;GO:0008236//serine-type peptidase activity","GO:0006509//membrane protein ectodomain proteolysis;GO:0007596//blood coagulation;GO:0043547//positive regulation of GTPase activity;GO:0045217//cell-cell junction maintenance;GO:0019730//antimicrobial humoral response;GO:0072672//neutrophil extravasation;GO:0006508//proteolysis;GO:0097029//mature conventional dendritic cell differentiation;GO:0043312//neutrophil degranulation;GO:0050765//negative regulation of phagocytosis;GO:0008284//positive regulation of cell proliferation;GO:0030574//collagen catabolic process","K01350//myeloblastin [EC:3.4.21.76]","NP_002768.3//myeloblastin precursor [Homo sapiens]","3//A2MP1"]
[64284,2018,0.04,0.08,1,0.734662616315091,"*",0.623548,"RAB17","GO:0070062//extracellular exosome;GO:0030425//dendrite;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0005622//intracellular;GO:0042470//melanosome;GO:0043025//neuronal cell body;GO:0055038//recycling endosome membrane;GO:0030139//endocytic vesicle;GO:0055037//recycling endosome;GO:0005769//early endosome;GO:0005886//plasma membrane","GO:0019003//GDP binding;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0046847//filopodium assembly;GO:0030100//regulation of endocytosis;GO:0051963//regulation of synapse assembly;GO:0060271//cilium assembly;GO:0032401//establishment of melanosome localization;GO:0050773//regulation of dendrite development;GO:0032402//melanosome transport;GO:0002415//immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor;GO:0032456//endocytic recycling;GO:0015031//protein transport;GO:0045056//transcytosis;GO:0051489//regulation of filopodium assembly","K07909//Ras-related protein Rab-17","NP_071894.1//ras-related protein Rab-17 [Homo sapiens]","3//A2MP1"]
[339896,3655,0.01,0.02,1,0.648672566360159,"*",0.499032,"GADL1","NA","GO:0004068//aspartate 1-decarboxylase activity;GO:0004782//sulfinoalanine decarboxylase activity;GO:0030170//pyridoxal phosphate binding","GO:0019752//carboxylic acid metabolic process","K18966//sulfinoalanine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.29 4.1.1.11]","XP_021522121.1//acidic amino acid decarboxylase GADL1 [Aotus nancymaae]","2//1"]
[5244,3826,0.01,0.02,1,0.648514250569476,"*",0.499032,"ABCB4","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005654//nucleoplasm;GO:0005925//focal adhesion;GO:0016324//apical plasma membrane;GO:0030136//clathrin-coated vesicle;GO:0031526//brush border membrane;GO:0046581//intercellular canaliculus;GO:0005737//cytoplasm;GO:0045121//membrane raft;GO:0005887//integral component of plasma membrane;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0005886//plasma membrane","GO:0090554//phosphatidylcholine-translocating ATPase activity;GO:0005524//ATP binding;GO:0042626//ATPase activity, coupled to transmembrane movement of substances;GO:0008559//xenobiotic transmembrane transporting ATPase activity;GO:0008525//phosphatidylcholine transporter activity;GO:0005548//phospholipid transporter activity","GO:0009914//hormone transport;GO:0001890//placenta development;GO:0036146//cellular response to mycotoxin;GO:0035633//maintenance of permeability of blood-brain barrier;GO:0050892//intestinal absorption;GO:0007420//brain development;GO:1903416//response to glycoside;GO:0045332//phospholipid translocation;GO:0097068//response to thyroxine;GO:1904478//regulation of intestinal absorption;GO:0019216//regulation of lipid metabolic process;GO:2001140//positive regulation of phospholipid transport;GO:0033189//response to vitamin A;GO:0042493//response to drug;GO:0032782//bile acid secretion;GO:1901557//response to fenofibrate;GO:0032376//positive regulation of cholesterol transport;GO:0033280//response to vitamin D;GO:1905235//response to quercetin;GO:0001666//response to hypoxia;GO:0071549//cellular response to dexamethasone stimulus;GO:0046686//response to cadmium ion;GO:0046618//drug export;GO:0043215//daunorubicin transport;GO:0055088//lipid homeostasis;GO:0006629//lipid metabolic process;GO:1990963//establishment of blood-retinal barrier;GO:0007595//lactation;GO:0061092//positive regulation of phospholipid translocation;GO:0033231//carbohydrate export;GO:0043278//response to morphine;GO:0071475//cellular hyperosmotic salinity response;GO:2001025//positive regulation of response to drug;GO:1905231//cellular response to borneol;GO:1905233//response to codeine;GO:0006810//transport;GO:0007623//circadian rhythm;GO:0055085//transmembrane transport;GO:0071217//cellular response to external biotic stimulus;GO:0071236//cellular response to antibiotic;GO:1990962//drug transport across blood-brain barrier;GO:1905232//cellular response to L-glutamate;GO:0060856//establishment of blood-brain barrier;GO:1905237//response to cyclosporin A;GO:0097327//response to antineoplastic agent;GO:1903413//cellular response to bile acid;GO:0060548//negative regulation of cell death;GO:0071312//cellular response to alkaloid;GO:0071392//cellular response to estradiol stimulus","K05659//ATP-binding cassette, subfamily B (MDR/TAP), member 4 [EC:3.6.3.44]","NP_061338.1//phosphatidylcholine translocator ABCB4 isoform C [Homo sapiens];EAW76949.1//ATP-binding cassette, sub-family B (MDR/TAP), member 4, isoform CRA_e [Homo sapiens]","3//A2MP1;2//1"]
[9947,4337,0.01,0.02,1,0.648145147410359,"*",0.499032,"MAGEC1","NA","NA","NA","K12464//melanoma-associated antigen D1","NP_005453.2//melanoma-associated antigen C1 [Homo sapiens]",4]
[387357,3983,0.03,0.06,1,0.734608433660299,"*",0.623548,"THEMIS","GO:0005634//nucleus;GO:0008180//COP9 signalosome;GO:0005911//cell-cell junction;GO:0005737//cytoplasm","NA","GO:0050852//T cell receptor signaling pathway;GO:0043383//negative T cell selection;GO:0043368//positive T cell selection;GO:0002250//adaptive immune response","NA","NP_001010923.1//protein THEMIS isoform 2 [Homo sapiens];NP_001158157.1//protein THEMIS isoform 1 [Homo sapiens]","1//3;2//1"]
[494470,4852,0.01,0.02,1,0.648092452682927,"*",0.499032,"RNF165","NA","GO:0008270//zinc ion binding","NA","K17821//RING finger protein 165","XP_011930057.1//PREDICTED: RING finger protein 165 isoform X2 [Cercocebus atys];XP_017713340.1//PREDICTED: RING finger protein 165 isoform X1 [Rhinopithecus bieti]","1//3;2//1"]
[127534,2840,0.03,0.06,1,0.73455425899705,"*",0.623548,"GJB4","GO:0005634//nucleus;GO:0005922//connexin complex;GO:0005730//nucleolus;GO:0016021//integral component of membrane;GO:0030054//cell junction","NA","GO:0007608//sensory perception of smell;GO:0042048//olfactory behavior;GO:0007154//cell communication","K07623//gap junction beta-4 protein","NP_694944.1//gap junction beta-4 protein [Homo sapiens]","2//1"]
[10633,1504,0.11,0.22,1,0.609040615722368,"*",0.451538,"RASL10A","GO:0016020//membrane;GO:0005730//nucleolus;GO:0005886//plasma membrane","GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0007165//signal transduction;GO:0007264//small GTPase mediated signal transduction","K07850//Ras-like protein family member 10A","XP_017820280.1//PREDICTED: ras-like protein family member 10A [Callithrix jacchus]",4]
[495,3582,0.01,0.02,1,0.647934419897586,"*",0.499032,"ATP4A","NA","NA","NA","K01542//H+/K+-exchanging ATPase alpha polypeptide [EC:3.6.3.10]","XP_020832639.1//potassium-transporting ATPase alpha chain 1 [Phascolarctos cinereus]","2//1"]
[5067,4963,0.01,0.02,1,0.647829107517269,"*",0.499032,"CNTN3","NA","NA","NA","K06761//contactin 3","XP_015315007.1//PREDICTED: contactin-3 [Bos taurus]","2//1"]
[3574,1903,0.04,0.08,1,0.734445933638107,"*",0.623548,"IL7","GO:0005615//extracellular space;GO:0005576//extracellular region","GO:0008083//growth factor activity;GO:0005125//cytokine activity;GO:0005139//interleukin-7 receptor binding","GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0010468//regulation of gene expression;GO:0048873//homeostasis of number of cells within a tissue;GO:0030890//positive regulation of B cell proliferation;GO:0046622//positive regulation of organ growth;GO:0006959//humoral immune response;GO:0045582//positive regulation of T cell differentiation;GO:0043086//negative regulation of catalytic activity;GO:0045453//bone resorption;GO:0007267//cell-cell signaling;GO:0043066//negative regulation of apoptotic process;GO:0038111//interleukin-7-mediated signaling pathway;GO:0009887//animal organ morphogenesis;GO:0006955//immune response;GO:0002360//T cell lineage commitment;GO:0008284//positive regulation of cell proliferation","K05431//interleukin 7","NP_001186817.1//interleukin-7 isoform 4 precursor [Homo sapiens];NP_000871.1//interleukin-7 isoform 1 precursor [Homo sapiens];NP_001186815.1//interleukin-7 isoform 2 precursor [Homo sapiens];NP_001186816.1//interleukin-7 isoform 3 precursor [Homo sapiens]","1//3;3//A2MP1"]
[943,3616,0.02,0.04,1,0.734337640224123,"*",0.623548,"TNFRSF8","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0043005//neuron projection","GO:0004888//transmembrane signaling receptor activity;GO:0048406//nerve growth factor binding;GO:0005031//tumor necrosis factor-activated receptor activity","GO:0045556//positive regulation of TRAIL biosynthetic process;GO:0007165//signal transduction;GO:0071260//cellular response to mechanical stimulus;GO:0097190//apoptotic signaling pathway;GO:0032496//response to lipopolysaccharide;GO:0006954//inflammatory response;GO:0042535//positive regulation of tumor necrosis factor biosynthetic process;GO:0043065//positive regulation of apoptotic process;GO:0010977//negative regulation of neuron projection development;GO:0006955//immune response;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0007411//axon guidance;GO:0008285//negative regulation of cell proliferation","K05145//tumor necrosis factor receptor superfamily member 8","XP_011540743.1//PREDICTED: tumor necrosis factor receptor superfamily member 8 isoform X1 [Homo sapiens];NP_001234.3//tumor necrosis factor receptor superfamily member 8 isoform 1 precursor [Homo sapiens]","4;2//1"]
[100129543,2367,0.01,0.02,1,0.999908343859649,"*",0.999032,"ZNF730","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_012364882.1//PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 726 [Nomascus leucogenys]","1//3"]
[79132,2631,0.03,0.06,1,0.734283505492075,"*",0.623548,"DHX58","GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0016787//hydrolase activity;GO:0005524//ATP binding;GO:0008270//zinc ion binding;GO:0004386//helicase activity;GO:0003725//double-stranded RNA binding;GO:0003727//single-stranded RNA binding","GO:0039536//negative regulation of RIG-I signaling pathway;GO:0045824//negative regulation of innate immune response;GO:0032481//positive regulation of type I interferon production;GO:0039534//negative regulation of MDA-5 signaling pathway;GO:0051607//defense response to virus;GO:0045088//regulation of innate immune response;GO:0016032//viral process;GO:1900245//positive regulation of MDA-5 signaling pathway;GO:1900246//positive regulation of RIG-I signaling pathway;GO:0032480//negative regulation of type I interferon production;GO:0009615//response to virus;GO:0045087//innate immune response","K12649//ATP-dependent RNA helicase DHX58 [EC:3.6.3.14]","NP_077024.2//probable ATP-dependent RNA helicase DHX58 [Homo sapiens]","2//1"]
[728378,4337,0.02,0.04,1,0.73422937874097,"*",0.623548,"POTEF","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0072562//blood microparticle;GO:0005938//cell cortex","NA","GO:0021762//substantia nigra development;GO:0001895//retina homeostasis","K17299//POTE ankyrin domain family protein","NP_001093241.1//POTE ankyrin domain family member F [Homo sapiens]","2//1"]
[1001,3704,0.02,0.04,1,0.734121149174528,"*",0.623548,"CDH3","GO:0005913//cell-cell adherens junction;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0005509//calcium ion binding","GO:0048023//positive regulation of melanin biosynthetic process;GO:0051796//negative regulation of timing of catagen;GO:0060901//regulation of hair cycle by canonical Wnt signaling pathway;GO:0007601//visual perception;GO:0031424//keratinization;GO:0032912//negative regulation of transforming growth factor beta2 production;GO:0043568//positive regulation of insulin-like growth factor receptor signaling pathway;GO:1902910//positive regulation of melanosome transport;GO:0022405//hair cycle process;GO:0032773//positive regulation of monophenol monooxygenase activity;GO:0042493//response to drug;GO:0042060//wound healing;GO:0001895//retina homeostasis;GO:0010838//positive regulation of keratinocyte proliferation;GO:0010628//positive regulation of gene expression;GO:0007155//cell adhesion;GO:0060070//canonical Wnt signaling pathway;GO:0034332//adherens junction organization;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules","K06796//cadherin 3, type 1, P-cadherin","NP_001784.2//cadherin-3 isoform 1 preproprotein [Homo sapiens];NP_001304124.1//cadherin-3 isoform 2 precursor [Homo sapiens]","1//3;5"]
[101060211,820,0.1,0.2,1,0.734067046355664,"*",0.623548,"CT45A7","NA","NA","NA","K13180//ATP-dependent RNA helicase DDX26B [EC:3.6.4.-]","NP_001017438.2//cancer/testis antigen family 45 member A6 [Homo sapiens]","1//3"]
[131368,3639,0.01,0.02,1,0.647460783625731,"*",0.499032,"ZPLD1","GO:0016021//integral component of membrane;GO:0005578//proteinaceous extracellular matrix;GO:0030659//cytoplasmic vesicle membrane","NA","NA","K18274//uromodulin","NP_778226.1//zona pellucida-like domain-containing protein 1 isoform 1 precursor [Homo sapiens];XP_007984141.1//PREDICTED: zona pellucida-like domain-containing protein 1 isoform X1 [Chlorocebus sabaeus]","1//3"]
[1908,2630,0.03,0.06,1,0.734012951510685,"*",0.623548,"EDN3","GO:0005615//extracellular space;GO:0005622//intracellular;GO:0005576//extracellular region","GO:0031708//endothelin B receptor binding;GO:0005102//receptor binding;GO:0005179//hormone activity","GO:0010468//regulation of gene expression;GO:0010961//cellular magnesium ion homeostasis;GO:0019229//regulation of vasoconstriction;GO:1901381//positive regulation of potassium ion transmembrane transport;GO:0042310//vasoconstriction;GO:0007166//cell surface receptor signaling pathway;GO:0014826//vein smooth muscle contraction;GO:0048016//inositol phosphate-mediated signaling;GO:0045840//positive regulation of mitotic nuclear division;GO:0045597//positive regulation of cell differentiation;GO:0006874//cellular calcium ion homeostasis;GO:0030318//melanocyte differentiation;GO:0030182//neuron differentiation;GO:0030072//peptide hormone secretion;GO:0010460//positive regulation of heart rate;GO:0007165//signal transduction;GO:0001755//neural crest cell migration;GO:0030593//neutrophil chemotaxis;GO:0003100//regulation of systemic arterial blood pressure by endothelin;GO:0043406//positive regulation of MAP kinase activity;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0007267//cell-cell signaling;GO:0048070//regulation of developmental pigmentation;GO:0008015//blood circulation;GO:0046887//positive regulation of hormone secretion;GO:0007275//multicellular organism development;GO:0008284//positive regulation of cell proliferation","K05227//endothelin-3","XP_018872366.1//PREDICTED: endothelin-3 isoform X1 [Gorilla gorilla gorilla];NP_996917.1//endothelin-3 isoform 1 preproprotein [Homo sapiens];NP_996916.1//endothelin-3 isoform 3 preproprotein [Homo sapiens];NP_996915.1//endothelin-3 isoform 2 preproprotein [Homo sapiens];NP_001289385.1//endothelin-3 isoform 5 preproprotein [Homo sapiens]","1//3;2//1"]
[84734,969,1.36,2.72,1,0.0495004678518519,"*",0.020917,"FAM167B","NA","NA","NA","K03129//transcription initiation factor TFIID subunit 4;K09993//cyclin-dependent kinase inhibitor 1C","XP_012497726.1//PREDICTED: protein FAM167B [Propithecus coquereli]","2//1"]
[2911,6672,0.01,0.02,1,0.393352057295268,"*",0.249274,"GRM1","GO:0030425//dendrite;GO:0005634//nucleus;GO:0014069//postsynaptic density;GO:0005887//integral component of plasma membrane;GO:0042734//presynaptic membrane;GO:0038038//G-protein coupled receptor homodimeric complex;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0099583//neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration;GO:0008066//glutamate receptor activity;GO:0004930//G-protein coupled receptor activity","GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway;GO:0071257//cellular response to electrical stimulus;GO:0000187//activation of MAPK activity;GO:0051966//regulation of synaptic transmission, glutamatergic;GO:0007216//G-protein coupled glutamate receptor signaling pathway;GO:0038042//dimeric G-protein coupled receptor signaling pathway;GO:0007626//locomotory behavior;GO:0051930//regulation of sensory perception of pain;GO:0019233//sensory perception of pain;GO:0007196//adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway;GO:0000186//activation of MAPKK activity","K04603//metabotropic glutamate receptor 1","XP_005961848.1//PREDICTED: metabotropic glutamate receptor 1-like isoform X3 [Pantholops hodgsonii];XP_005659220.1//metabotropic glutamate receptor 1 isoform X2 [Sus scrofa];XP_018885733.1//PREDICTED: metabotropic glutamate receptor 1 isoform X1 [Gorilla gorilla gorilla]","1//3"]
[2,4684,0.01,0.02,1,0.647197951449217,"*",0.499032,"A2M","GO:0070062//extracellular exosome;GO:0072562//blood microparticle","GO:0043120//tumor necrosis factor binding;GO:0002020//protease binding;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005102//receptor binding;GO:0048306//calcium-dependent protein binding;GO:0019959//interleukin-8 binding;GO:0019966//interleukin-1 binding","GO:0048863//stem cell differentiation;GO:0001869//negative regulation of complement activation, lectin pathway","K03910//alpha-2-macroglobulin","XP_017749746.1//PREDICTED: alpha-2-macroglobulin isoform X2 [Rhinopithecus bieti];XP_007965730.1//PREDICTED: alpha-2-macroglobulin isoform X2 [Chlorocebus sabaeus];XP_011920110.1//PREDICTED: alpha-2-macroglobulin isoform X2 [Cercocebus atys]","1//3;5"]
[256158,15670,0.01,0.02,1,0.127623744637123,"*",0.062198,"HMCN2","NA","NA","NA","K17341//hemicentin","NP_001278744.1//hemicentin-2 precursor [Homo sapiens]","1//3"]
[2857,1938,0.04,0.08,1,0.733958864637831,"*",0.623548,"GPR34","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0045028//G-protein coupled purinergic nucleotide receptor activity;GO:0004930//G-protein coupled receptor activity","GO:0007186//G-protein coupled receptor signaling pathway","K08383//G protein-coupled receptor 34","NP_005291.1//probable G-protein coupled receptor 34 [Homo sapiens]","1//3;3//A2MP1"]
[80125,2039,0.1,0.2,1,0.496117612417174,"*",0.342164,"CCDC33","NA","NA","NA","K03006//DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6];K14000//ribosome-binding protein 1","NP_001274110.1//coiled-coil domain-containing protein 33 isoform 3 [Homo sapiens];NP_877592.2//coiled-coil domain-containing protein 33 isoform 2 [Homo sapiens];NP_079331.3//coiled-coil domain-containing protein 33 isoform 1 [Homo sapiens]","1//3;4;3//A2MP1"]
[7010,4343,0.01,0.02,1,0.647040354545454,"*",0.499032,"TEK","GO:0016323//basolateral plasma membrane;GO:0005815//microtubule organizing center;GO:0005925//focal adhesion;GO:0016324//apical plasma membrane;GO:0005902//microvillus;GO:0005737//cytoplasm;GO:0009925//basal plasma membrane;GO:0005884//actin filament;GO:0001725//stress fiber;GO:0009986//cell surface;GO:0045121//membrane raft;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0004713//protein tyrosine kinase activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005524//ATP binding;GO:0004872//receptor activity;GO:0004672//protein kinase activity;GO:0019838//growth factor binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity","GO:2000351//regulation of endothelial cell apoptotic process;GO:0010595//positive regulation of endothelial cell migration;GO:0043627//response to estrogen;GO:0050728//negative regulation of inflammatory response;GO:1902533//positive regulation of intracellular signal transduction;GO:0045766//positive regulation of angiogenesis;GO:0051259//protein oligomerization;GO:0001935//endothelial cell proliferation;GO:0034446//substrate adhesion-dependent cell spreading;GO:0007165//signal transduction;GO:0001525//angiogenesis;GO:0051894//positive regulation of focal adhesion assembly;GO:0007507//heart development;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0043066//negative regulation of apoptotic process;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:0048014//Tie signaling pathway;GO:0001666//response to hypoxia;GO:0046777//protein autophosphorylation;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0002040//sprouting angiogenesis;GO:0051897//positive regulation of protein kinase B signaling;GO:0032878//regulation of establishment or maintenance of cell polarity;GO:0043114//regulation of vascular permeability;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0060216//definitive hemopoiesis;GO:0001934//positive regulation of protein phosphorylation;GO:0001938//positive regulation of endothelial cell proliferation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:2000251//positive regulation of actin cytoskeleton reorganization;GO:0072012//glomerulus vasculature development;GO:0001958//endochondral ossification;GO:0000165//MAPK cascade;GO:0016525//negative regulation of angiogenesis;GO:0050900//leukocyte migration;GO:0043434//response to peptide hormone;GO:0007267//cell-cell signaling;GO:0051591//response to cAMP;GO:0060347//heart trabecula formation;GO:0070374//positive regulation of ERK1 and ERK2 cascade","K05121//endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]","NP_001277006.1//angiopoietin-1 receptor isoform 2 precursor [Homo sapiens];NP_001277007.1//angiopoietin-1 receptor isoform 3 precursor [Homo sapiens];BAD92033.1//TEK tyrosine kinase variant, partial [Homo sapiens]","1//3;4"]
[2313,3995,0.01,0.02,1,0.646830344693281,"*",0.499032,"FLI1","GO:0005634//nucleus;GO:0016604//nuclear body;GO:0005829//cytosol","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0043565//sequence-specific DNA binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0008015//blood circulation;GO:0009887//animal organ morphogenesis;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0035855//megakaryocyte development;GO:0030154//cell differentiation;GO:0006351//transcription, DNA-templated;GO:0007599//hemostasis;GO:0045893//positive regulation of transcription, DNA-templated","K09436//friend leukemia integration 1 transcription factor","XP_012627744.1//Friend leukemia integration 1 transcription factor isoform X2 [Microcebus murinus];NP_001257941.1//Friend leukemia integration 1 transcription factor isoform 4 [Homo sapiens];EFB27417.1//hypothetical protein PANDA_000485, partial [Ailuropoda melanoleuca]","1//3;4;2//1"]
[121601,3819,0.01,0.02,1,0.646777863529412,"*",0.499032,"ANO4","GO:0005622//intracellular;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005229//intracellular calcium activated chloride channel activity;GO:0017128//phospholipid scramblase activity;GO:0046983//protein dimerization activity","GO:0061591//calcium activated galactosylceramide scrambling;GO:0061589//calcium activated phosphatidylserine scrambling;GO:0061590//calcium activated phosphatidylcholine scrambling","K19499//anoctamin-4","XP_011536218.1//PREDICTED: anoctamin-4 isoform X5 [Homo sapiens];XP_009424372.1//PREDICTED: anoctamin-4 isoform X3 [Pan troglodytes];XP_011536213.1//PREDICTED: anoctamin-4 isoform X1 [Homo sapiens]","1//3;3//A2MP1"]
[1910,4490,0.02,0.04,1,0.733904785735337,"*",0.623548,"EDNRB","GO:0031965//nuclear membrane;GO:0045121//membrane raft;GO:0005887//integral component of plasma membrane;GO:0005622//intracellular;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0031702//type 1 angiotensin receptor binding;GO:0017046//peptide hormone binding;GO:0004962//endothelin receptor activity","GO:0008217//regulation of blood pressure;GO:0014043//negative regulation of neuron maturation;GO:0006885//regulation of pH;GO:0071222//cellular response to lipopolysaccharide;GO:0007166//cell surface receptor signaling pathway;GO:0019233//sensory perception of pain;GO:0048246//macrophage chemotaxis;GO:0060406//positive regulation of penile erection;GO:0001755//neural crest cell migration;GO:0019722//calcium-mediated signaling;GO:0086100//endothelin receptor signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0050678//regulation of epithelial cell proliferation;GO:0051930//regulation of sensory perception of pain;GO:0007422//peripheral nervous system development;GO:0007399//nervous system development;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0014070//response to organic cyclic compound;GO:0042310//vasoconstriction;GO:0035645//enteric smooth muscle cell differentiation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0014826//vein smooth muscle contraction;GO:0042045//epithelial fluid transport;GO:0019934//cGMP-mediated signaling;GO:0007194//negative regulation of adenylate cyclase activity;GO:0048265//response to pain;GO:0001934//positive regulation of protein phosphorylation;GO:0031620//regulation of fever generation;GO:0030318//melanocyte differentiation;GO:0042311//vasodilation;GO:0007497//posterior midgut development;GO:0032269//negative regulation of cellular protein metabolic process;GO:0007568//aging;GO:0048484//enteric nervous system development;GO:0035815//positive regulation of renal sodium excretion;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0035810//positive regulation of urine volume;GO:0008284//positive regulation of cell proliferation","K04198//endothelin receptor type B","NP_003982.1//endothelin receptor type B isoform 2 precursor [Homo sapiens];NP_001188326.1//endothelin receptor type B isoform 3 [Homo sapiens];XP_014976756.1//PREDICTED: endothelin B receptor isoform X1 [Macaca mulatta]","4;1//3;3//A2MP1;2//1"]
[25834,7772,0.01,0.02,1,0.733850714801444,"*",0.623548,"MGAT4C","NA","NA","NA","K13748//alpha-1,3-mannosylglycoprotein beta-1,4-N-acetylglucosaminyltransferase C [EC:2.4.1.201 2.4.1.145]","XP_008002375.1//PREDICTED: alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C isoform X3 [Chlorocebus sabaeus];XP_014202736.1//PREDICTED: alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C isoform X1 [Pan paniscus];XP_008002369.1//PREDICTED: alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C isoform X1 [Chlorocebus sabaeus];XP_010353828.1//PREDICTED: alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C isoform X1 [Rhinopithecus roxellana];NP_001338211.1//alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C isoform a precursor [Homo sapiens]","1//3;4"]
[23236,7103,0.01,0.02,1,0.393157866903634,"*",0.249274,"PLCB1","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0031965//nuclear membrane;GO:0016607//nuclear speck;GO:0043209//myelin sheath;GO:0000790//nuclear chromatin;GO:0005737//cytoplasm;GO:0005829//cytosol","GO:0004435//phosphatidylinositol phospholipase C activity;GO:0042803//protein homodimerization activity;GO:0004629//phospholipase C activity;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0005521//lamin binding;GO:0005509//calcium ion binding;GO:0004871//signal transducer activity;GO:0005516//calmodulin binding;GO:0019899//enzyme binding;GO:0005096//GTPase activator activity","GO:0046330//positive regulation of JNK cascade;GO:0040019//positive regulation of embryonic development;GO:0080154//regulation of fertilization;GO:0060466//activation of meiosis involved in egg activation;GO:0070498//interleukin-1-mediated signaling pathway;GO:0007420//brain development;GO:2000560//positive regulation of CD24 biosynthetic process;GO:0021987//cerebral cortex development;GO:0007215//glutamate receptor signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0007213//G-protein coupled acetylcholine receptor signaling pathway;GO:0007165//signal transduction;GO:0046488//phosphatidylinositol metabolic process;GO:0045663//positive regulation of myoblast differentiation;GO:0051726//regulation of cell cycle;GO:0016042//lipid catabolic process;GO:0048639//positive regulation of developmental growth;GO:0048009//insulin-like growth factor receptor signaling pathway;GO:0035556//intracellular signal transduction;GO:0045893//positive regulation of transcription, DNA-templated;GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0032735//positive regulation of interleukin-12 production;GO:0007223//Wnt signaling pathway, calcium modulating pathway;GO:0035722//interleukin-12-mediated signaling pathway;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle;GO:2000344//positive regulation of acrosome reaction;GO:2000438//negative regulation of monocyte extravasation;GO:0007613//memory;GO:0043647//inositol phosphate metabolic process;GO:0035723//interleukin-15-mediated signaling pathway;GO:0045444//fat cell differentiation;GO:0000086//G2/M transition of mitotic cell cycle","K05858//phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]","NP_877398.1//1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform b [Homo sapiens];NP_056007.1//1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform a [Homo sapiens]","3//A2MP1;2//1"]
[23148,4778,0.1,0.2,1,0.28568350367893,"*",0.1657694,"NACAD","GO:0005634//nucleus;GO:0005854//nascent polypeptide-associated complex","NA","GO:0015031//protein transport","K03626//nascent polypeptide-associated complex subunit alpha","NP_001139806.1//NAC-alpha domain-containing protein 1 [Homo sapiens]","1//3"]
[407,1331,0.06,0.12,1,0.733742596832412,"*",0.623548,"ARR3","GO:0001917//photoreceptor inner segment;GO:0045202//synapse;GO:0001750//photoreceptor outer segment;GO:0005737//cytoplasm","GO:0002046//opsin binding;GO:0051219//phosphoprotein binding","GO:0001932//regulation of protein phosphorylation;GO:0007165//signal transduction;GO:0006897//endocytosis;GO:0007601//visual perception","K13801//arrestin-C","XP_017722533.1//PREDICTED: arrestin-C isoform X2 [Rhinopithecus bieti]","2//1"]
[9353,8033,0.01,0.02,1,0.393080244422507,"*",0.249274,"SLIT2","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0009986//cell surface;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0043237//laminin-1 binding;GO:0042802//identical protein binding;GO:0005095//GTPase inhibitor activity;GO:0005509//calcium ion binding;GO:0008201//heparin binding;GO:0048495//Roundabout binding;GO:0042803//protein homodimerization activity;GO:0043394//proteoglycan binding","GO:0031290//retinal ganglion cell axon guidance;GO:0070100//negative regulation of chemokine-mediated signaling pathway;GO:0050929//induction of negative chemotaxis;GO:0071672//negative regulation of smooth muscle cell chemotaxis;GO:0090260//negative regulation of retinal ganglion cell axon guidance;GO:0043065//positive regulation of apoptotic process;GO:0043116//negative regulation of vascular permeability;GO:0007411//axon guidance;GO:0048754//branching morphogenesis of an epithelial tube;GO:0051414//response to cortisol;GO:0008045//motor neuron axon guidance;GO:0050772//positive regulation of axonogenesis;GO:0010593//negative regulation of lamellipodium assembly;GO:0071504//cellular response to heparin;GO:0090288//negative regulation of cellular response to growth factor stimulus;GO:0061364//apoptotic process involved in luteolysis;GO:0001933//negative regulation of protein phosphorylation;GO:0021972//corticospinal neuron axon guidance through spinal cord;GO:0021836//chemorepulsion involved in postnatal olfactory bulb interneuron migration;GO:0050919//negative chemotaxis;GO:0090024//negative regulation of neutrophil chemotaxis;GO:0002042//cell migration involved in sprouting angiogenesis;GO:0090027//negative regulation of monocyte chemotaxis;GO:0030308//negative regulation of cell growth;GO:0048846//axon extension involved in axon guidance;GO:0035385//Roundabout signaling pathway;GO:0010596//negative regulation of endothelial cell migration;GO:0030336//negative regulation of cell migration;GO:0002689//negative regulation of leukocyte chemotaxis;GO:0032870//cellular response to hormone stimulus;GO:0030837//negative regulation of actin filament polymerization;GO:0014912//negative regulation of smooth muscle cell migration;GO:0001657//ureteric bud development;GO:0051058//negative regulation of small GTPase mediated signal transduction;GO:0071676//negative regulation of mononuclear cell migration","K06839//slit 2","NP_001276064.1//slit homolog 2 protein isoform 2 precursor [Homo sapiens];NP_004778.1//slit homolog 2 protein isoform 1 precursor [Homo sapiens];NP_001276065.1//slit homolog 2 protein isoform 3 precursor [Homo sapiens]","3//A2MP1;2//1"]
[10874,834,0.22,0.44,1,0.608886376160729,"*",0.451538,"NMU","GO:0005576//extracellular region;GO:0043195//terminal bouton","GO:0042922//neuromedin U receptor binding;GO:0005102//receptor binding","GO:2000821//regulation of grooming behavior;GO:2000252//negative regulation of feeding behavior;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007165//signal transduction;GO:0050806//positive regulation of synaptic transmission;GO:0042755//eating behavior;GO:0007586//digestion;GO:0006940//regulation of smooth muscle contraction;GO:0045187//regulation of circadian sleep/wake cycle, sleep;GO:0045987//positive regulation of smooth muscle contraction;GO:0046887//positive regulation of hormone secretion;GO:0009648//photoperiodism;GO:0019233//sensory perception of pain;GO:0007218//neuropeptide signaling pathway;GO:0001696//gastric acid secretion","K05249//neuromedin U","NP_001278975.1//neuromedin-U isoform 3 precursor [Homo sapiens];NP_006672.1//neuromedin-U isoform 1 preproprotein [Homo sapiens];NP_001278974.1//neuromedin-U isoform 2 precursor [Homo sapiens]","1//3;3//A2MP1"]
[84229,2731,0.03,0.06,1,0.733688549793754,"*",0.623548,"DRC7","GO:0005856//cytoskeleton;GO:0031514//motile cilium;GO:0005737//cytoplasm","NA","NA","K03006//DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6];K18402//PHD finger protein 20;K09380//zinc finger homeobox protein 4","NP_115645.4//dynein regulatory complex subunit 7 isoform a [Homo sapiens];NP_001276092.1//dynein regulatory complex subunit 7 isoform b [Homo sapiens]","1//3;5"]
[729759,939,0.01,0.02,1,0.999657803056878,"*",0.999032,"OR4F29","NA","NA","NA","K04257//olfactory receptor","XP_011933019.1//PREDICTED: olfactory receptor 4F3/4F16/4F29 [Cercocebus atys]","2//1"]
[90342,6497,0.01,0.02,1,0.392692591321499,"*",0.249274,"FER1L5","NA","NA","NA","K22126//fer-1-like protein 5","XP_014968368.1//PREDICTED: fer-1-like protein 5 isoform X1 [Macaca mulatta]","1//3"]
[84066,897,0.09,0.18,1,0.733634510716653,"*",0.623548,"TEX35","GO:0005634//nucleus;GO:0015630//microtubule cytoskeleton","NA","NA","NA","NP_001164195.1//testis-expressed protein 35 isoform 4 [Homo sapiens];NP_001164193.1//testis-expressed protein 35 isoform 2 [Homo sapiens];NP_115502.2//testis-expressed protein 35 isoform 1 [Homo sapiens];NP_001164194.1//testis-expressed protein 35 isoform 3 [Homo sapiens]","1//3;4"]
[55867,3900,0.07,0.14,1,0.364365031787811,"*",0.225316,"SLC22A11","GO:0070062//extracellular exosome;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016324//apical plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0015143//urate transmembrane transporter activity;GO:0005452//inorganic anion exchanger activity;GO:0008514//organic anion transmembrane transporter activity;GO:0022857//transmembrane transporter activity;GO:0015347//sodium-independent organic anion transmembrane transporter activity","GO:0043252//sodium-independent organic anion transport;GO:0015711//organic anion transport;GO:0015747//urate transport;GO:0046415//urate metabolic process","K08207//MFS transporter, OCT family, solute carrier family 22 (organic anion/cation transporter), member 11","NP_001294914.1//solute carrier family 22 member 11 isoform 2 [Homo sapiens];NP_060954.1//solute carrier family 22 member 11 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[27439,5043,0.05,0.1,1,0.628705025050568,"*",0.505908,"TMEM121B","GO:0016021//integral component of membrane","NA","NA","K03006//DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6];K06236//collagen, type I, alpha","NP_114096.1//cat eye syndrome critical region protein 6 isoform a [Homo sapiens];XP_011544427.1//PREDICTED: cat eye syndrome critical region protein 6 isoform X2 [Homo sapiens]","1//3;3//A2MP1"]
[81399,939,0.01,0.02,1,0.99953257973193,"*",0.999032,"OR4F16","NA","NA","NA","K04257//olfactory receptor","XP_011933019.1//PREDICTED: olfactory receptor 4F3/4F16/4F29 [Cercocebus atys]","1//3"]
[375759,1624,0.05,0.1,1,0.733580479599352,"*",0.623548,"C9orf50","NA","NA","NA","K16628//collagen, type VII, alpha","NP_955382.3//uncharacterized protein C9orf50 [Homo sapiens]","3//A2MP1"]
[8788,4465,0.01,0.02,1,0.644685577678932,"*",0.499032,"DLK1","GO:0005615//extracellular space;GO:0016021//integral component of membrane","GO:0005509//calcium ion binding","GO:0030154//cell differentiation;GO:0045746//negative regulation of Notch signaling pathway","K06051//delta","NP_001304101.1//protein delta homolog 1 isoform 2 preproprotein [Homo sapiens];NP_003827.3//protein delta homolog 1 isoform 1 preproprotein [Homo sapiens]","6;1//3"]
[9843,4284,0.01,0.02,1,0.644529201811125,"*",0.499032,"HEPH","GO:0016323//basolateral plasma membrane;GO:0005622//intracellular;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0048471//perinuclear region of cytoplasm","GO:0004322//ferroxidase activity;GO:0005507//copper ion binding;GO:0016491//oxidoreductase activity;GO:0008198//ferrous iron binding","GO:0006879//cellular iron ion homeostasis;GO:0006826//iron ion transport;GO:0006825//copper ion transport","K14735//hephaestin [EC:1.16.3.1]","NP_001269070.1//hephaestin isoform d precursor [Homo sapiens];NP_620074.3//hephaestin isoform a [Homo sapiens];Q9BQS7.3//RecName: Full=Hephaestin; Flags: Precursor;XP_011529375.1//PREDICTED: hephaestin isoform X1 [Homo sapiens]","1//3;4;3//A2MP1"]
[8110,4077,0.01,0.02,1,0.644372901786436,"*",0.499032,"DPF3","GO:0005654//nucleoplasm;GO:0071565//nBAF complex","GO:0046872//metal ion binding;GO:0008270//zinc ion binding;GO:0003676//nucleic acid binding","GO:0007399//nervous system development;GO:0006355//regulation of transcription, DNA-templated;GO:0016569//covalent chromatin modification;GO:0006351//transcription, DNA-templated","K22198//BRG1-associated factor 45B/C","NP_001267472.1//zinc finger protein DPF3 isoform 3 [Homo sapiens];NP_001267473.1//zinc finger protein DPF3 isoform 4 [Homo sapiens];NP_036206.3//zinc finger protein DPF3 isoform 1 [Homo sapiens];NP_001267471.1//zinc finger protein DPF3 isoform 2 [Homo sapiens]","1//3;4"]
[2672,4512,0.02,0.04,1,0.733364434692976,"*",0.623548,"GFI1","NA","GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0051569//regulation of histone H3-K4 methylation;GO:0030097//hemopoiesis","K09228//KRAB domain-containing zinc finger protein","XP_017890293.1//PREDICTED: zinc finger protein Gfi-1b-like [Ceratina calcarata]","4;2//1"]
[113835,3671,0.01,0.02,1,0.644008496364518,"*",0.499032,"ZNF257","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_009433435.2//PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 257 [Pan troglodytes]","1//3;3//A2MP1"]
[253738,4412,0.01,0.02,1,0.643904456219709,"*",0.499032,"EBF3","GO:0005634//nucleus","GO:0003677//DNA binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0006355//regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007275//multicellular organism development;GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated","K09103//early B-cell factor","BAD90316.1//mKIAA4201 protein, partial [Mus musculus]","2//1"]
[64333,2355,0.03,0.06,1,0.733256459952886,"*",0.623548,"ARHGAP9","GO:0034774//secretory granule lumen;GO:0005829//cytosol;GO:0005576//extracellular region","GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0005096//GTPase activator activity","GO:0007165//signal transduction;GO:0043312//neutrophil degranulation;GO:0051056//regulation of small GTPase mediated signal transduction","K20634//Rho GTPase-activating protein 9","NP_001306779.1//rho GTPase-activating protein 9 isoform 4 [Homo sapiens];EAW97015.1//Rho GTPase activating protein 9, isoform CRA_b [Homo sapiens];NP_115885.2//rho GTPase-activating protein 9 isoform 1 [Homo sapiens];EAW97016.1//Rho GTPase activating protein 9, isoform CRA_c [Homo sapiens];XP_019598008.1//PREDICTED: rho GTPase-activating protein 9 isoform X1 [Rhinolophus sinicus];Q9BRR9.2//RecName: Full=Rho GTPase-activating protein 9; AltName: Full=Rho-type GTPase-activating protein 9","1//3;3//A2MP1;2//1"]
[196883,3415,0.01,0.02,1,0.643696476744186,"*",0.499032,"ADCY4","GO:0016020//membrane;GO:0030425//dendrite;GO:0005622//intracellular;GO:0016021//integral component of membrane;GO:0008074//guanylate cyclase complex, soluble;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0005524//ATP binding;GO:0000166//nucleotide binding;GO:0004016//adenylate cyclase activity;GO:0004383//guanylate cyclase activity","GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0071377//cellular response to glucagon stimulus;GO:0007165//signal transduction;GO:0035556//intracellular signal transduction;GO:0006171//cAMP biosynthetic process;GO:0006182//cGMP biosynthetic process;GO:0007190//activation of adenylate cyclase activity;GO:0034199//activation of protein kinase A activity;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0003091//renal water homeostasis;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway","K08044//adenylate cyclase 4 [EC:4.6.1.1]","CAD62613.1//unnamed protein product, partial [Homo sapiens]","1//3;3//A2MP1"]
[84106,2235,0.07,0.14,1,0.608783593180284,"*",0.451538,"PRAM1","GO:0043234//protein complex","GO:0008289//lipid binding;GO:0019901//protein kinase binding","GO:0007165//signal transduction;GO:0007229//integrin-mediated signaling pathway;GO:0043313//regulation of neutrophil degranulation","K19994//PML-RARA-regulated adapter molecule 1","NP_115528.4//PML-RARA-regulated adapter molecule 1 [Homo sapiens]",4]
[158376,1546,0.05,0.1,1,0.733094557444616,"*",0.623548,"SPAAR","GO:0031902//late endosome membrane;GO:1905103//integral component of lysosomal membrane","NA","GO:0043416//regulation of skeletal muscle tissue regeneration;GO:1904262//negative regulation of TORC1 signaling;GO:0071230//cellular response to amino acid stimulus","NA","EAW58322.1//hCG1652354 [Homo sapiens]","1//3"]
[79632,3821,0.01,0.02,1,0.643332835767896,"*",0.499032,"FAM184A","GO:0005615//extracellular space","NA","NA","K16464//centrosomal protein CEP250;K20283//golgin subfamily A member 4;K16469//rootletin;K20478//golgin subfamily B member 1","NP_078857.5//protein FAM184A isoform 1 [Homo sapiens];XP_009450182.2//PREDICTED: protein FAM184A isoform X4 [Pan troglodytes];XP_009450183.2//PREDICTED: protein FAM184A isoform X5 [Pan troglodytes]","1//3;2//1;5"]
[3784,3262,0.05,0.1,1,0.608680844894515,"*",0.451538,"KCNQ1","GO:0016323//basolateral plasma membrane;GO:0005783//endoplasmic reticulum;GO:0005770//late endosome;GO:0005764//lysosome;GO:0005737//cytoplasm;GO:0034702//ion channel complex;GO:0045121//membrane raft;GO:0005886//plasma membrane;GO:0005769//early endosome;GO:0008076//voltage-gated potassium channel complex;GO:0030659//cytoplasmic vesicle membrane","GO:0015271//outward rectifier potassium channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0086008//voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization;GO:0005251//delayed rectifier potassium channel activity;GO:0034237//protein kinase A regulatory subunit binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0097110//scaffold protein binding;GO:0086089//voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization;GO:0044325//ion channel binding;GO:1902282//voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization;GO:0005516//calmodulin binding;GO:0034236//protein kinase A catalytic subunit binding;GO:0008157//protein phosphatase 1 binding","GO:1902260//negative regulation of delayed rectifier potassium channel activity;GO:0086013//membrane repolarization during cardiac muscle cell action potential;GO:0035690//cellular response to drug;GO:0006349//regulation of gene expression by genetic imprinting;GO:1901381//positive regulation of potassium ion transmembrane transport;GO:0070293//renal absorption;GO:0050892//intestinal absorption;GO:0071320//cellular response to cAMP;GO:0072358//cardiovascular system development;GO:0008016//regulation of heart contraction;GO:0060048//cardiac muscle contraction;GO:0071435//potassium ion export;GO:0048839//inner ear development;GO:0060453//regulation of gastric acid secretion;GO:0060307//regulation of ventricular cardiac muscle cell membrane repolarization;GO:0086005//ventricular cardiac muscle cell action potential;GO:0010460//positive regulation of heart rate;GO:0061337//cardiac conduction;GO:1903817//negative regulation of voltage-gated potassium channel activity;GO:0016458//gene silencing;GO:0071872//cellular response to epinephrine stimulus;GO:0086091//regulation of heart rate by cardiac conduction;GO:0060452//positive regulation of cardiac muscle contraction;GO:0098914//membrane repolarization during atrial cardiac muscle cell action potential;GO:0097623//potassium ion export across plasma membrane;GO:0098915//membrane repolarization during ventricular cardiac muscle cell action potential;GO:0007605//sensory perception of sound;GO:0060306//regulation of membrane repolarization;GO:0060372//regulation of atrial cardiac muscle cell membrane repolarization;GO:0086014//atrial cardiac muscle cell action potential;GO:0071805//potassium ion transmembrane transport;GO:0086011//membrane repolarization during action potential","K04926//potassium voltage-gated channel KQT-like subfamily member 1","NP_861463.1//potassium voltage-gated channel subfamily KQT member 1 isoform 2 precursor [Homo sapiens];NP_000209.2//potassium voltage-gated channel subfamily KQT member 1 isoform 1 [Homo sapiens]","1//3;2//1"]
[56963,3058,0.05,0.1,1,0.608629483756645,"*",0.451538,"RGMA","GO:0070062//extracellular exosome;GO:0009986//cell surface;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0031225//anchored component of membrane;GO:0043005//neuron projection","GO:0005102//receptor binding;GO:1990459//transferrin receptor binding;GO:0015026//coreceptor activity","GO:0030510//regulation of BMP signaling pathway;GO:1900121//negative regulation of receptor binding;GO:0048671//negative regulation of collateral sprouting;GO:0048681//negative regulation of axon regeneration;GO:0051044//positive regulation of membrane protein ectodomain proteolysis;GO:0010976//positive regulation of neuron projection development;GO:0043547//positive regulation of GTPase activity;GO:0030509//BMP signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0031175//neuron projection development;GO:0001843//neural tube closure","K06847//RGM domain family","NP_064596.2//repulsive guidance molecule A isoform 3 [Homo sapiens];AAH15886.2//RGMA protein, partial [Homo sapiens];NP_001159755.1//repulsive guidance molecule A isoform 1 [Homo sapiens]","1//3;2//1"]
[2984,3850,0.01,0.02,1,0.642865900645161,"*",0.499032,"GUCY2C","GO:0016021//integral component of membrane;GO:0008074//guanylate cyclase complex, soluble;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane","GO:0005524//ATP binding;GO:0015643//toxic substance binding;GO:0004672//protein kinase activity;GO:0005525//GTP binding;GO:0004383//guanylate cyclase activity","GO:0006182//cGMP biosynthetic process;GO:0007165//signal transduction;GO:0007586//digestion;GO:0042127//regulation of cell proliferation;GO:0035556//intracellular signal transduction;GO:0007168//receptor guanylyl cyclase signaling pathway;GO:0009636//response to toxic substance","K12320//heat-stable enterotoxin receptor [EC:4.6.1.2]","NP_004954.2//heat-stable enterotoxin receptor precursor [Homo sapiens]","3//A2MP1"]
[6753,3764,0.01,0.02,1,0.642347878162772,"*",0.499032,"SSTR3","GO:0060170//ciliary membrane;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0097730//non-motile cilium;GO:0043005//neuron projection","GO:0005102//receptor binding;GO:0042923//neuropeptide binding;GO:0004994//somatostatin receptor activity;GO:0004930//G-protein coupled receptor activity","GO:0021549//cerebellum development;GO:0071385//cellular response to glucocorticoid stimulus;GO:0007267//cell-cell signaling;GO:0007283//spermatogenesis;GO:0042594//response to starvation;GO:0030900//forebrain development;GO:0007268//chemical synaptic transmission;GO:0008628//hormone-mediated apoptotic signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0008285//negative regulation of cell proliferation;GO:0071392//cellular response to estradiol stimulus;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger","K04219//somatostatin receptor 3","XP_003821603.1//PREDICTED: somatostatin receptor type 3 [Pan paniscus];NP_001042.1//somatostatin receptor type 3 [Homo sapiens]","4;2//1"]
[55799,3689,0.01,0.02,1,0.64219263417385,"*",0.499032,"CACNA2D3","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005244//voltage-gated ion channel activity;GO:0046872//metal ion binding;GO:0005262//calcium channel activity","GO:0061337//cardiac conduction","K04860//voltage-dependent calcium channel alpha-2/delta-3","NP_060868.2//voltage-dependent calcium channel subunit alpha-2/delta-3 precursor [Homo sapiens]","2//1"]
[353189,5334,0.03,0.06,1,0.608578131285859,"*",0.451538,"SLCO4C1","GO:0070062//extracellular exosome;GO:0016323//basolateral plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane;GO:0005886//plasma membrane;GO:0035577//azurophil granule membrane","GO:0005215//transporter activity;GO:0015347//sodium-independent organic anion transmembrane transporter activity","GO:0043252//sodium-independent organic anion transport;GO:0030154//cell differentiation;GO:0007275//multicellular organism development;GO:0043312//neutrophil degranulation;GO:0006811//ion transport;GO:0007283//spermatogenesis","K14355//solute carrier organic anion transporter family, member 4C","NP_851322.3//solute carrier organic anion transporter family member 4C1 [Homo sapiens]",4]
[24138,4034,3.89,7.78,1,{"v":3.03389188299817e-15,"d":"3.03E-15"},"Up",{"v":2.0778E-16,"d":"2.08E-16"},"IFIT5","GO:0043231//intracellular membrane-bounded organelle;GO:0015629//actin cytoskeleton;GO:0032587//ruffle membrane;GO:0045177//apical part of cell;GO:0005886//plasma membrane;GO:0008385//IkappaB kinase complex;GO:0042597//periplasmic space","GO:0003723//RNA binding;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0000339//RNA cap binding;GO:0008266//poly(U) RNA binding;GO:0000049//tRNA binding;GO:0003690//double-stranded DNA binding;GO:0003727//single-stranded RNA binding","GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045071//negative regulation of viral genome replication;GO:0051607//defense response to virus;GO:0045087//innate immune response","K14217//interferon-induced protein with tetratricopeptide repeats 1","NP_036552.1//interferon-induced protein with tetratricopeptide repeats 5 [Homo sapiens]","2//1"]
[392509,1132,0.07,0.14,1,0.732878798616732,"*",0.623548,"ARL13A","GO:0005622//intracellular","GO:0005525//GTP binding","GO:0007264//small GTPase mediated signal transduction","K07961//ADP-ribosylation factor-like protein 13","NP_001155963.1//ADP-ribosylation factor-like protein 13A [Homo sapiens]","1//3"]
[4744,3721,0.01,0.02,1,0.641727352117211,"*",0.499032,"NEFH","GO:0030424//axon;GO:0097418//neurofibrillary tangle;GO:0005883//neurofilament;GO:0043209//myelin sheath;GO:0005739//mitochondrion;GO:0014069//postsynaptic density;GO:0005737//cytoplasm","GO:0070840//dynein complex binding;GO:0030674//protein binding, bridging;GO:0005198//structural molecule activity;GO:0005200//structural constituent of cytoskeleton;GO:0019894//kinesin binding;GO:0008017//microtubule binding;GO:0019901//protein kinase binding","GO:0000226//microtubule cytoskeleton organization;GO:0061564//axon development;GO:0033693//neurofilament bundle assembly;GO:0007409//axonogenesis;GO:1990830//cellular response to leukemia inhibitory factor;GO:0048936//peripheral nervous system neuron axonogenesis;GO:0030031//cell projection assembly;GO:1902513//regulation of organelle transport along microtubule","K04574//neurofilament heavy polypeptide","NP_066554.2//neurofilament heavy polypeptide [Homo sapiens]","3//A2MP1"]
[169044,6365,0.01,0.02,1,0.39203533287388,"*",0.249274,"COL22A1","GO:0005788//endoplasmic reticulum lumen;GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005578//proteinaceous extracellular matrix","NA","NA","K16630//collagen, type XXII, alpha","NP_690848.1//collagen alpha-1(XXII) chain precursor [Homo sapiens]","2//1"]
[23533,4368,0.01,0.02,1,0.641211162162162,"*",0.499032,"PIK3R5","GO:0005944//phosphatidylinositol 3-kinase complex, class IB;GO:0016020//membrane;GO:0005634//nucleus;GO:0005815//microtubule organizing center;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005942//phosphatidylinositol 3-kinase complex;GO:0005886//plasma membrane","GO:0031683//G-protein beta/gamma-subunit complex binding;GO:0046935//1-phosphatidylinositol-3-kinase regulator activity;GO:0016301//kinase activity;GO:0046934//phosphatidylinositol-4,5-bisphosphate 3-kinase activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0051897//positive regulation of protein kinase B signaling;GO:0043406//positive regulation of MAP kinase activity;GO:0030168//platelet activation;GO:0006661//phosphatidylinositol biosynthetic process;GO:0014065//phosphatidylinositol 3-kinase signaling","K21290//phosphoinositide-3-kinase regulatory subunit 5/6","NP_055123.2//phosphoinositide 3-kinase regulatory subunit 5 isoform 1 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[54102,4102,0.01,0.02,1,0.640953378467476,"*",0.499032,"CLIC6","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0034707//chloride channel complex;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0005244//voltage-gated ion channel activity;GO:0005254//chloride channel activity","GO:1902476//chloride transmembrane transport","K05026//chloride intracellular channel protein 6","NP_444507.1//chloride intracellular channel protein 6 isoform 2 [Homo sapiens];NP_001303938.1//chloride intracellular channel protein 6 isoform 1 [Homo sapiens]","1//3;2//1"]
[2239,3714,0.01,0.02,1,0.64085032301632,"*",0.499032,"GPC4","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0009897//external side of plasma membrane;GO:0031225//anchored component of membrane;GO:0005578//proteinaceous extracellular matrix;GO:0005796//Golgi lumen;GO:0005887//integral component of plasma membrane;GO:0043202//lysosomal lumen;GO:0005886//plasma membrane","GO:0043395//heparan sulfate proteoglycan binding;GO:1904929//coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway","GO:0001523//retinoid metabolic process;GO:0009653//anatomical structure morphogenesis;GO:0008283//cell proliferation;GO:0006027//glycosaminoglycan catabolic process;GO:0006024//glycosaminoglycan biosynthetic process;GO:0030203//glycosaminoglycan metabolic process","K08110//glypican 4","NP_001439.2//glypican-4 precursor [Homo sapiens]","2//1"]
[3587,3672,0.01,0.02,1,0.640798807717042,"*",0.499032,"IL10RA","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004920//interleukin-10 receptor activity;GO:0004872//receptor activity;GO:0019969//interleukin-10 binding;GO:0004871//signal transducer activity","GO:0032496//response to lipopolysaccharide;GO:0050807//regulation of synapse organization","K05134//interleukin 10 receptor alpha","NP_001549.2//interleukin-10 receptor subunit alpha precursor [Homo sapiens]","3//A2MP1"]
[100507003,1557,0.05,0.1,1,0.732663166752483,"*",0.623548,"GFY","GO:0030173//integral component of Golgi membrane;GO:0016021//integral component of membrane","NA","GO:0007608//sensory perception of smell;GO:0097499//protein localization to non-motile cilium;GO:0050896//response to stimulus;GO:1905515//non-motile cilium assembly","K10955//mucin-2;K03006//DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6];K12567//titin [EC:2.7.11.1];K04574//neurofilament heavy polypeptide;K04006//decay accelerating factor","NP_001182185.1//Golgi-associated olfactory signaling regulator precursor [Homo sapiens]","1//3"]
[1003,4149,0.01,0.02,1,0.640541355403777,"*",0.499032,"CDH5","GO:0016020//membrane;GO:0009986//cell surface;GO:0009897//external side of plasma membrane;GO:0005913//cell-cell adherens junction;GO:0005911//cell-cell junction;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0005923//bicellular tight junction;GO:0005886//plasma membrane","GO:0044325//ion channel binding;GO:0005509//calcium ion binding;GO:0019903//protein phosphatase binding;GO:0005102//receptor binding;GO:0008013//beta-catenin binding","GO:0007179//transforming growth factor beta receptor signaling pathway;GO:2000114//regulation of establishment of cell polarity;GO:0007043//cell-cell junction assembly;GO:0034332//adherens junction organization;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:1903142//positive regulation of establishment of endothelial barrier;GO:0008285//negative regulation of cell proliferation;GO:0001955//blood vessel maturation","K06533//cadherin 5, type 2, VE-cadherin","BAD93145.1//cadherin 5, type 2 preproprotein variant, partial [Homo sapiens]",4]
[441308,939,0.01,0.02,1,0.999157097921362,"*",0.999032,"OR4F21","NA","NA","NA","K04257//olfactory receptor","XP_011933019.1//PREDICTED: olfactory receptor 4F3/4F16/4F29 [Cercocebus atys]","1//3"]
[3059,2050,0.04,0.08,1,0.732609278611356,"*",0.623548,"HCLS1","GO:0005634//nucleus;GO:0005667//transcription factor complex;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0003779//actin binding;GO:0017124//SH3 domain binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0019901//protein kinase binding;GO:0032403//protein complex binding","GO:0030833//regulation of actin filament polymerization;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0051897//positive regulation of protein kinase B signaling;GO:0006355//regulation of transcription, DNA-templated;GO:0035556//intracellular signal transduction;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0045651//positive regulation of macrophage differentiation;GO:0071345//cellular response to cytokine stimulus;GO:0030041//actin filament polymerization;GO:2000251//positive regulation of actin cytoskeleton reorganization;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0030854//positive regulation of granulocyte differentiation;GO:0030218//erythrocyte differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0009725//response to hormone;GO:2000107//negative regulation of leukocyte apoptotic process;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0008284//positive regulation of cell proliferation;GO:0042993//positive regulation of transcription factor import into nucleus","K06106//cortactin","NP_005326.2//hematopoietic lineage cell-specific protein isoform 1 [Homo sapiens];NP_001278970.1//hematopoietic lineage cell-specific protein isoform 2 [Homo sapiens]","1//3;5"]
[6096,3604,0.01,0.02,1,0.64048988976378,"*",0.499032,"RORB","GO:0005634//nucleus","GO:0003707//steroid hormone receptor activity;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0008270//zinc ion binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0008134//transcription factor binding;GO:0004879//nuclear receptor activity","GO:0046548//retinal rod cell development;GO:0042752//regulation of circadian rhythm;GO:0045668//negative regulation of osteoblast differentiation;GO:0006351//transcription, DNA-templated;GO:0046549//retinal cone cell development","K08533//RAR-related orphan receptor beta","AAA42095.1//transcription factor, partial [Rattus norvegicus]","3//A2MP1"]
[4917,1986,0.08,0.16,1,0.608475452336764,"*",0.451538,"NTN3","GO:0005794//Golgi apparatus;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix","GO:0005102//receptor binding","GO:0007411//axon guidance","K06844//netrin 3","NP_006172.1//netrin-3 precursor [Homo sapiens]","2//1"]
[1573,1927,0.04,0.08,1,0.73250152610678,"*",0.623548,"CYP2J2","GO:0070062//extracellular exosome","GO:0020037//heme binding;GO:0071614//linoleic acid epoxygenase activity;GO:0005506//iron ion binding;GO:0008405//arachidonic acid 11,12-epoxygenase activity;GO:0008404//arachidonic acid 14,15-epoxygenase activity;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen","GO:0043651//linoleic acid metabolic process;GO:0019373//epoxygenase P450 pathway","K07418//cytochrome P450 family 2 subfamily J [EC:1.14.14.1]","BAG37780.1//unnamed protein product [Homo sapiens]","3//A2MP1"]
[730755,880,0.19,0.38,1,0.60842412585407,"*",0.451538,"KRTAP2-3","GO:0005829//cytosol;GO:0045095//keratin filament","NA","GO:0031424//keratinization","K02893//large subunit ribosomal protein L23Ae;K00933//creatine kinase [EC:2.7.3.2]","NP_149440.1//keratin-associated protein 2-4 [Homo sapiens]","1//3"]
[137872,1907,0.17,0.34,1,0.407455246298789,"*",0.265328,"ADHFE1","GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0005739//mitochondrion","GO:0004022//alcohol dehydrogenase (NAD) activity;GO:0046872//metal ion binding;GO:0047988//hydroxyacid-oxoacid transhydrogenase activity","GO:0015993//molecular hydrogen transport;GO:0006103//2-oxoglutarate metabolic process","K11173//hydroxyacid-oxoacid transhydrogenase [EC:1.1.99.24]","NP_653251.2//hydroxyacid-oxoacid transhydrogenase, mitochondrial [Homo sapiens]","2//1"]
[145226,1934,0.04,0.08,1,0.732447661739834,"*",0.623548,"RDH12","GO:0060342//photoreceptor inner segment membrane;GO:0005622//intracellular","GO:0052650//NADP-retinol dehydrogenase activity;GO:0004745//retinol dehydrogenase activity;GO:0016491//oxidoreductase activity","GO:0001523//retinoid metabolic process;GO:0042572//retinol metabolic process;GO:0050896//response to stimulus;GO:0007601//visual perception;GO:0045494//photoreceptor cell maintenance","K11153//retinol dehydrogenase 12 [EC:1.1.1.300]","NP_689656.2//retinol dehydrogenase 12 precursor [Homo sapiens]","2//1"]
[139378,9931,0.01,0.02,1,0.732393805294118,"*",0.623548,"ADGRG4","GO:0016021//integral component of membrane","GO:0004930//G-protein coupled receptor activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0007166//cell surface receptor signaling pathway","K08455//G protein-coupled receptor 112","NP_722576.3//adhesion G-protein coupled receptor G4 [Homo sapiens]","3//A2MP1"]
[338872,1849,0.06,0.12,1,0.732232283466882,"*",0.623548,"C1QTNF9","NA","NA","NA","K06237//collagen, type IV, alpha","XP_017949521.1//PREDICTED: otolin-1 [Xenopus tropicalis]","4;1//3"]
[100128569,671,5.67,11.33,0.998727220878287,0.000368868721367521,"*",{"v":9.4561e-05,"d":"9.46E-05"},"C19orf71","NA","NA","NA","K10955//mucin-2","NP_001129052.1//uncharacterized protein C19orf71 [Homo sapiens]","1//3"]
[604,3286,3.15,6.29,0.99770818849201,{"v":2.83858834224599E-10,"d":"2.84E-10"},"*",{"v":2.9907e-11,"d":"2.99E-11"},"BCL6","GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0005657//replication fork","GO:0042802//identical protein binding;GO:0003682//chromatin binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0045591//positive regulation of regulatory T cell differentiation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0030308//negative regulation of cell growth;GO:0043065//positive regulation of apoptotic process;GO:0000060//protein import into nucleus, translocation;GO:0006974//cellular response to DNA damage stimulus","K15618//B-cell lymphoma 6 protein","XP_003256686.1//PREDICTED: B-cell lymphoma 6 protein [Nomascus leucogenys];XP_006156796.1//PREDICTED: B-cell lymphoma 6 protein isoform X2 [Tupaia chinensis]","4;1//3"]
[55150,765,2.3,4.59,0.996860292469433,0.0210742473161034,"*",0.0079632,"C19orf73","NA","NA","NA","NA","XP_010349484.1//PREDICTED: putative uncharacterized protein C19orf73 homolog [Saimiri boliviensis boliviensis]","2//1"]
[2323,1090,1.6,3.18,0.990954860396993,0.0210777393206297,"*",0.0079632,"FLT3LG","GO:0016020//membrane;GO:0005615//extracellular space;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0031233//intrinsic component of external side of plasma membrane","GO:0005125//cytokine activity;GO:0016301//kinase activity;GO:0030971//receptor tyrosine kinase binding;GO:0005102//receptor binding;GO:0042803//protein homodimerization activity","GO:0030098//lymphocyte differentiation;GO:0090290//positive regulation of osteoclast proliferation;GO:0007165//signal transduction;GO:0071866//negative regulation of apoptotic process in bone marrow;GO:0030885//regulation of myeloid dendritic cell activation;GO:0048873//homeostasis of number of cells within a tissue;GO:0035162//embryonic hemopoiesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0032825//positive regulation of natural killer cell differentiation;GO:0045663//positive regulation of myoblast differentiation;GO:0001934//positive regulation of protein phosphorylation;GO:1901741//positive regulation of myoblast fusion;GO:0045787//positive regulation of cell cycle;GO:0008284//positive regulation of cell proliferation;GO:0071864//positive regulation of cell proliferation in bone marrow","K05454//fms-related tyrosine kinase 3 ligand","XP_007995738.1//PREDICTED: fms-related tyrosine kinase 3 ligand isoform X1 [Chlorocebus sabaeus];NP_001450.2//fms-related tyrosine kinase 3 ligand isoform 1 precursor [Homo sapiens];EAW52488.1//fms-related tyrosine kinase 3 ligand, isoform CRA_a [Homo sapiens]","1//3;3//A2MP1"]
[6774,4955,35.33,70.19,0.990371754548179,{"v":1.19197308255319e-159,"d":"1.19E-159"},"*",{"v":3.50712E-162,"d":"3.51E-162"},"STAT3","NA","NA","NA","K04692//signal transducer and activator of transcription 3","XP_018883234.1//PREDICTED: signal transducer and activator of transcription 3 isoform X4 [Gorilla gorilla gorilla];XP_005369087.1//PREDICTED: signal transducer and activator of transcription 3 isoform X1 [Microtus ochrogaster];XP_006092427.1//PREDICTED: signal transducer and activator of transcription 3 isoform X1 [Myotis lucifugus]","1//3;3//A2MP1;2//1"]
[126374,2204,11.59,23,0.988753294825266,{"v":1.90208139643436E-23,"d":"1.90E-23"},"*",{"v":7.34684e-25,"d":"7.35E-25"},"WTIP","GO:0005634//nucleus;GO:0005667//transcription factor complex;GO:0005911//cell-cell junction;GO:0000932//P-body;GO:0005912//adherens junction","GO:0046872//metal ion binding;GO:0003714//transcription corepressor activity","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0035331//negative regulation of hippo signaling;GO:0030030//cell projection organization;GO:0001666//response to hypoxia;GO:0007010//cytoskeleton organization;GO:0035195//gene silencing by miRNA;GO:2000637//positive regulation of gene silencing by miRNA;GO:0022604//regulation of cell morphogenesis","K16682//LIM domain-containing protein","NP_001073905.1//Wilms tumor protein 1-interacting protein [Homo sapiens]","1//3"]
[440836,970,4.93,9.78,0.988246818574322,{"v":5.57194472953837e-05,"d":"5.57E-05"},"*",{"v":1.23166E-5,"d":"1.23E-05"},"ODF3B","NA","NA","NA","K10955//mucin-2;K13171//serine/arginine repetitive matrix protein 1","NP_001014440.2//outer dense fiber protein 3B [Homo sapiens]","3//A2MP1"]
[2113,5228,4.16,8.23,0.984308902280533,{"v":1.36707326500542E-17,"d":"1.37E-17"},"*",{"v":7.89914e-19,"d":"7.90E-19"},"ETS1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription factor complex;GO:0005737//cytoplasm","GO:0000982//transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0008134//transcription factor binding;GO:0003700//DNA binding transcription factor activity;GO:0035035//histone acetyltransferase binding","GO:0045786//negative regulation of cell cycle;GO:0060055//angiogenesis involved in wound healing;GO:0010595//positive regulation of endothelial cell migration;GO:0021854//hypothalamus development;GO:0050728//negative regulation of inflammatory response;GO:0044849//estrous cycle;GO:0046677//response to antibiotic;GO:0061614//pri-miRNA transcription from RNA polymerase II promoter;GO:0032355//response to estradiol;GO:0070555//response to interleukin-1;GO:0021983//pituitary gland development;GO:0045766//positive regulation of angiogenesis;GO:0070301//cellular response to hydrogen peroxide;GO:0008285//negative regulation of cell proliferation;GO:0009612//response to mechanical stimulus;GO:0007565//female pregnancy;GO:0010715//regulation of extracellular matrix disassembly;GO:0001666//response to hypoxia;GO:1904996//positive regulation of leukocyte adhesion to vascular endothelial cell;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045648//positive regulation of erythrocyte differentiation;GO:0050729//positive regulation of inflammatory response;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048870//cell motility;GO:0051272//positive regulation of cellular component movement;GO:0034616//response to laminar fluid shear stress;GO:0030578//PML body organization;GO:0006366//transcription from RNA polymerase II promoter;GO:0045765//regulation of angiogenesis;GO:0006955//immune response;GO:0042981//regulation of apoptotic process;GO:0008284//positive regulation of cell proliferation","K02678//C-ets-1","NP_005229.1//protein C-ets-1 isoform 2 [Homo sapiens];NP_001137292.1//protein C-ets-1 isoform 1 [Homo sapiens];XP_021782433.1//protein C-ets-1 isoform X6 [Papio anubis];XP_006072439.1//PREDICTED: transforming protein p68/c-ets-1 isoform X4 [Bubalus bubalis]","1//3;3//A2MP1"]
[28984,1126,0.44,0.87,0.983511877211431,0.285775997798403,"*",0.1657694,"RGCC","GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005813//centrosome;GO:0005737//cytoplasm","GO:0070412//R-SMAD binding;GO:0030295//protein kinase activator activity;GO:0019901//protein kinase binding","GO:0071456//cellular response to hypoxia;GO:0031659//positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle;GO:0003331//positive regulation of extracellular matrix constituent secretion;GO:0032967//positive regulation of collagen biosynthetic process;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:2000353//positive regulation of endothelial cell apoptotic process;GO:1901203//positive regulation of extracellular matrix assembly;GO:0045840//positive regulation of mitotic nuclear division;GO:0050710//negative regulation of cytokine secretion;GO:0008285//negative regulation of cell proliferation;GO:0001937//negative regulation of endothelial cell proliferation;GO:0006956//complement activation;GO:0072537//fibroblast activation;GO:0071850//mitotic cell cycle arrest;GO:0016525//negative regulation of angiogenesis;GO:0001100//negative regulation of exit from mitosis;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:1901991//negative regulation of mitotic cell cycle phase transition;GO:0010628//positive regulation of gene expression;GO:0051496//positive regulation of stress fiber assembly;GO:0071158//positive regulation of cell cycle arrest;GO:0090272//negative regulation of fibroblast growth factor production;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0051726//regulation of cell cycle;GO:2000573//positive regulation of DNA biosynthetic process;GO:0050715//positive regulation of cytokine secretion;GO:2000048//negative regulation of cell-cell adhesion mediated by cadherin;GO:0043537//negative regulation of blood vessel endothelial cell migration;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest","K05012//chloride channel 3/4/5;K04257//olfactory receptor","NP_054778.2//regulator of cell cycle RGCC [Homo sapiens]","2//1"]
[3903,2733,1.83,3.61,0.980155188603128,{"v":2.17338763359708E-5,"d":"2.17E-05"},"*",{"v":4.47086e-06,"d":"4.47E-06"},"LAIR1","GO:0070062//extracellular exosome;GO:0035579//specific granule membrane;GO:0016021//integral component of membrane;GO:0070821//tertiary granule membrane;GO:0005886//plasma membrane","NA","GO:0043312//neutrophil degranulation;GO:0050776//regulation of immune response;GO:0002250//adaptive immune response","K06725//leukocyte-associated Ig-like receptor","EAW72235.1//leukocyte-associated Ig-like receptor 1, isoform CRA_c, partial [Homo sapiens];NP_068352.2//leukocyte-associated immunoglobulin-like receptor 1 isoform b precursor [Homo sapiens];NP_001275952.2//leukocyte-associated immunoglobulin-like receptor 1 isoform c precursor [Homo sapiens];NP_002278.2//leukocyte-associated immunoglobulin-like receptor 1 isoform a precursor [Homo sapiens];NP_001275954.2//leukocyte-associated immunoglobulin-like receptor 1 isoform e precursor [Homo sapiens]","4;2//1;5"]
[8676,5509,0.34,0.67,0.978626349207433,0.0150432928307107,"*",5.44606E-3,"STX11","GO:0008021//synaptic vesicle;GO:0005794//Golgi apparatus;GO:0031201//SNARE complex;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0000149//SNARE binding;GO:0005484//SNAP receptor activity","GO:0006886//intracellular protein transport;GO:0061025//membrane fusion;GO:0031629//synaptic vesicle fusion to presynaptic active zone membrane;GO:0048278//vesicle docking","K08487//syntaxin 11","XP_011534515.1//PREDICTED: syntaxin-11 isoform X1 [Homo sapiens]","3//A2MP1"]
[330,6932,3.8,7.47,0.975108824458289,{"v":3.16875215529906e-17,"d":"3.17E-17"},"*",{"v":1.89046E-18,"d":"1.89E-18"},"BIRC3","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0045121//membrane raft;GO:0043234//protein complex;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process;GO:0016740//transferase activity;GO:0004842//ubiquitin-protein transferase activity","GO:0034121//regulation of toll-like receptor signaling pathway;GO:0038061//NIK/NF-kappaB signaling;GO:0060544//regulation of necroptotic process;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:2000116//regulation of cysteine-type endopeptidase activity;GO:0007166//cell surface receptor signaling pathway;GO:0007283//spermatogenesis;GO:0010803//regulation of tumor necrosis factor-mediated signaling pathway;GO:0070424//regulation of nucleotide-binding oligomerization domain containing signaling pathway;GO:0016579//protein deubiquitination;GO:1990001//inhibition of cysteine-type endopeptidase activity involved in apoptotic process;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0051291//protein heterooligomerization;GO:0031398//positive regulation of protein ubiquitination;GO:0043066//negative regulation of apoptotic process;GO:0060546//negative regulation of necroptotic process;GO:0045088//regulation of innate immune response;GO:0039535//regulation of RIG-I signaling pathway;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0050727//regulation of inflammatory response;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0042981//regulation of apoptotic process","K16060//baculoviral IAP repeat-containing protein 2/3","NP_001156.1//baculoviral IAP repeat-containing protein 3 [Homo sapiens]","4;2//1"]
[100130370,1200,0.21,0.41,0.965234581839323,0.496162648511256,"*",0.342164,"LOC100130370","NA","NA","NA","K17985//activating molecule in BECN1-regulated autophagy protein 1;K04948//cyclic nucleotide gated channel alpha 1;K01064//wingless-type MMTV integration site family, member 9","XP_011522444.1//PREDICTED: uncharacterized protein LOC100130370 isoform X4 [Homo sapiens]","1//3;2//1"]
[161835,2813,0.21,0.41,0.965234581839323,0.236865272450805,"*",0.1326232,"FSIP1","NA","NA","NA","K12327//caldesmon;K03104//signal recognition particle subunit SRP14;K20478//golgin subfamily B member 1","NP_689810.3//fibrous sheath-interacting protein 1 [Homo sapiens];XP_008015275.1//PREDICTED: fibrous sheath-interacting protein 1 isoform X1 [Chlorocebus sabaeus]","1//3;4"]
[84985,4461,0.21,0.41,0.965234581839323,0.130671499657056,"*",0.0644032,"FAM83A","GO:0005737//cytoplasm","GO:0036312//phosphatidylinositol 3-kinase regulatory subunit binding;GO:0019901//protein kinase binding","GO:0008283//cell proliferation;GO:0007173//epidermal growth factor receptor signaling pathway","K16805//protein FAM83D","NP_001275516.1//protein FAM83A isoform c [Homo sapiens];NP_001308559.1//protein FAM83A isoform d [Homo sapiens];NP_116288.2//protein FAM83A isoform a [Homo sapiens];NP_996889.1//protein FAM83A isoform b [Homo sapiens]","6;1//3;2//1"]
[388524,1578,0.19,0.37,0.961525852185364,0.495757617777778,"*",0.342164,"RPSAP58","GO:0030686//90S preribosome;GO:0005634//nucleus;GO:0022627//cytosolic small ribosomal subunit;GO:0005886//plasma membrane","GO:0005055//laminin receptor activity;GO:0003735//structural constituent of ribosome;GO:0043236//laminin binding","GO:0000028//ribosomal small subunit assembly;GO:0007155//cell adhesion;GO:0006407//rRNA export from nucleus;GO:0000461//endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006412//translation;GO:0000447//endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)","K02998//small subunit ribosomal protein SAe","XP_004835182.2//40S ribosomal protein SA [Heterocephalus glaber]","1//3"]
[7453,2555,65.35,127.04,0.959023676460162,{"v":2.45121767261538e-137,"d":"2.45E-137"},"*",{"v":9.97428e-140,"d":"9.97E-140"},"WARS","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0043234//protein complex;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0004830//tryptophan-tRNA ligase activity;GO:0019904//protein domain specific binding;GO:0005524//ATP binding;GO:0019210//kinase inhibitor activity;GO:0042803//protein homodimerization activity;GO:0019901//protein kinase binding","GO:0001525//angiogenesis;GO:0010835//regulation of protein ADP-ribosylation;GO:0010628//positive regulation of gene expression;GO:0006469//negative regulation of protein kinase activity;GO:0001933//negative regulation of protein phosphorylation;GO:0031334//positive regulation of protein complex assembly;GO:0045765//regulation of angiogenesis;GO:0006418//tRNA aminoacylation for protein translation;GO:0006436//tryptophanyl-tRNA aminoacylation;GO:0006412//translation;GO:0008285//negative regulation of cell proliferation","K01867//tryptophanyl-tRNA synthetase [EC:6.1.1.2]","NP_004175.2//tryptophan--tRNA ligase, cytoplasmic isoform a [Homo sapiens]","1//3;3//A2MP1"]
[3429,652,0.17,0.33,0.956931278108114,0.735476316325777,"*",0.623548,"IFI27","GO:0005637//nuclear inner membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane","GO:0001102//RNA polymerase II activating transcription factor binding;GO:0005521//lamin binding","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0060337//type I interferon signaling pathway;GO:0097190//apoptotic signaling pathway;GO:0046825//regulation of protein export from nucleus;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process","NA","XP_011806935.1//PREDICTED: interferon alpha-inducible protein 27, mitochondrial isoform X1 [Colobus angolensis palliatus]","4;1//3;2//1"]
[6692,2361,0.17,0.33,0.956931278108114,0.344465990080595,"*",0.208698,"SPINT1","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0004867//serine-type endopeptidase inhibitor activity","GO:0060670//branching involved in labyrinthine layer morphogenesis;GO:0045687//positive regulation of glial cell differentiation;GO:0030198//extracellular matrix organization;GO:0001843//neural tube closure;GO:2000178//negative regulation of neural precursor cell proliferation;GO:0071773//cellular response to BMP stimulus;GO:0060674//placenta blood vessel development","K15619//Kunitz-type protease inhibitor 1","NP_003701.1//kunitz-type protease inhibitor 1 isoform 2 precursor [Homo sapiens];NP_857593.1//kunitz-type protease inhibitor 1 isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1;2//1"]
[137075,1972,5.25,10.18,0.95534823352221,{"v":2.8824571392271e-09,"d":"2.88E-09"},"*",{"v":3.40864e-10,"d":"3.41E-10"},"CLDN23","GO:0016021//integral component of membrane;GO:0005923//bicellular tight junction;GO:0005886//plasma membrane","GO:0042802//identical protein binding;GO:0005198//structural molecule activity","GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules","K06087//claudin","NP_919260.2//claudin-23 [Homo sapiens]","2//1"]
[11219,1255,0.97,1.88,0.95467600949051,0.078118285467706,"*",0.0351322,"TREX2","NA","NA","NA","K10791//three prime repair exonuclease 2 [EC:3.1.11.2]","XP_011857628.1//PREDICTED: three prime repair exonuclease 2 [Mandrillus leucophaeus]","3//A2MP1"]
[4207,1978,0.32,0.62,0.954196310386875,0.176900398895426,"*",0.0922376,"BORCS8-MEF2B","GO:0005634//nucleus;GO:0005667//transcription factor complex","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0042826//histone deacetylase binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0046983//protein dimerization activity","GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0007517//muscle organ development","K09261//MADS-box transcription enhancer factor 2B","XP_011720253.1//PREDICTED: myocyte-specific enhancer factor 2B isoform X1 [Macaca nemestrina]","3//A2MP1"]
[3576,1585,9.39,18.18,0.953155136540332,{"v":3.78331275158085e-15,"d":"3.78E-15"},"*",{"v":2.62184e-16,"d":"2.62E-16"},"CXCL8","GO:0005615//extracellular space;GO:0005622//intracellular;GO:0005576//extracellular region","GO:0045236//CXCR chemokine receptor binding;GO:0005153//interleukin-8 receptor binding;GO:0008009//chemokine activity","GO:2000535//regulation of entry of bacterium into host cell;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0050930//induction of positive chemotaxis;GO:0031623//receptor internalization;GO:0042127//regulation of cell proliferation;GO:0034976//response to endoplasmic reticulum stress;GO:0071222//cellular response to lipopolysaccharide;GO:0071356//cellular response to tumor necrosis factor;GO:0071347//cellular response to interleukin-1;GO:0045766//positive regulation of angiogenesis;GO:0008285//negative regulation of cell proliferation;GO:0007165//signal transduction;GO:0001525//angiogenesis;GO:0019722//calcium-mediated signaling;GO:0070098//chemokine-mediated signaling pathway;GO:0031640//killing of cells of other organism;GO:0048566//embryonic digestive tract development;GO:0032496//response to lipopolysaccharide;GO:0035556//intracellular signal transduction;GO:0045744//negative regulation of G-protein coupled receptor protein signaling pathway;GO:0007050//cell cycle arrest;GO:0002237//response to molecule of bacterial origin;GO:0006935//chemotaxis;GO:0030155//regulation of cell adhesion;GO:0007186//G-protein coupled receptor signaling pathway;GO:0042119//neutrophil activation;GO:0030593//neutrophil chemotaxis;GO:0090023//positive regulation of neutrophil chemotaxis;GO:0006954//inflammatory response;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0045091//regulation of single stranded viral RNA replication via double stranded DNA intermediate;GO:0006928//movement of cell or subcellular component;GO:0006955//immune response;GO:0036499//PERK-mediated unfolded protein response","K10030//interleukin 8","NP_000575.1//interleukin-8 isoform 1 precursor [Homo sapiens];NP_001341769.1//interleukin-8 isoform 2 precursor [Homo sapiens]","1//3;3//A2MP1"]
[51265,1588,0.45,0.87,0.951090399519054,0.221462158109658,"*",0.1208656,"CDKL3","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity","GO:0050775//positive regulation of dendrite morphogenesis;GO:0097484//dendrite extension;GO:0006464//cellular protein modification process;GO:0030517//negative regulation of axon extension;GO:0006468//protein phosphorylation","K08824//cyclin-dependent kinase-like [EC:2.7.11.22]","XP_009447950.1//PREDICTED: cyclin-dependent kinase-like 3 isoform X11 [Pan troglodytes];XP_016865026.1//PREDICTED: cyclin-dependent kinase-like 3 isoform X11 [Homo sapiens];XP_016865021.1//PREDICTED: cyclin-dependent kinase-like 3 isoform X6 [Homo sapiens];XP_011541731.1//PREDICTED: cyclin-dependent kinase-like 3 isoform X3 [Homo sapiens];NP_001107047.1//cyclin-dependent kinase-like 3 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[9853,4853,27.74,53.58,0.949726793518776,{"v":4.68615608807339e-89,"d":"4.69E-89"},"*",{"v":3.19764e-91,"d":"3.20E-91"},"RUSC2","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0031410//cytoplasmic vesicle","GO:0017137//Rab GTPase binding","NA","K03006//DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6];K12384//lysosome membrane protein 2;K22016//mucin-3/17","AAH64843.1//RUSC2 protein, partial [Homo sapiens];NP_055621.1//iporin isoform 1 [Homo sapiens]","1//3;4"]
[11147,817,19.14,36.93,0.948202432719588,{"v":4.84267784e-13,"d":"4.84E-13"},"*",{"v":3.94108e-14,"d":"3.94E-14"},"HHLA3","NA","NA","NA","NA","NP_001026863.1//HERV-H LTR-associating protein 3 isoform 1 [Homo sapiens];XP_016804779.1//PREDICTED: HERV-H LTR-associating protein 3, partial [Pan troglodytes]","1//3;2//1"]
[2875,1896,0.42,0.81,0.947532580105865,0.185227842792686,"*",0.097658,"GPT","NA","NA","NA","K00814//alanine transaminase [EC:2.6.1.2]","XP_016815647.1//PREDICTED: alanine aminotransferase 1 isoform X4 [Pan troglodytes]","2//1"]
[333926,1762,0.14,0.27,0.947532580105864,0.496072584498094,"*",0.342164,"PPM1J","NA","GO:0004722//protein serine/threonine phosphatase activity","NA","K17504//protein phosphatase 1J [EC:3.1.3.16]","XP_017725223.1//PREDICTED: protein phosphatase 1J isoform X2 [Rhinopithecus bieti]",5]
[57664,3092,0.56,1.08,0.947532580105864,0.0308508815663982,"*",0.01223104,"PLEKHA4","GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0032266//phosphatidylinositol-3-phosphate binding","GO:0006661//phosphatidylinositol biosynthetic process","K12822//RNA-binding protein 25","NP_065955.2//pleckstrin homology domain-containing family A member 4 isoform 1 [Homo sapiens];NP_001154826.1//pleckstrin homology domain-containing family A member 4 isoform 2 [Homo sapiens]","1//3;2//1"]
[56147,2726,0.14,0.27,0.947532580105864,0.176857930908654,"*",0.0922376,"PCDHA1","NA","NA","NA","K16493//protocadherin alpha","XP_019518209.1//PREDICTED: protocadherin alpha-1 isoform X5 [Hipposideros armiger];XP_011715029.1//PREDICTED: protocadherin alpha-2 [Macaca nemestrina];XP_018882539.1//PREDICTED: protocadherin alpha-10 isoform X13 [Gorilla gorilla gorilla]","3//A2MP1;2//1"]
[197259,2779,7.89,15.21,0.946922947711038,{"v":1.0170178070922E-16,"d":"1.02E-16"},"*",{"v":6.28394e-18,"d":"6.28E-18"},"MLKL","GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0042802//identical protein binding;GO:0004871//signal transducer activity;GO:0019901//protein kinase binding;GO:0032403//protein complex binding","GO:0070266//necroptotic process;GO:0035556//intracellular signal transduction;GO:0070207//protein homotrimerization","K08849//mixed lineage kinase domain-like [EC:2.7.11.1]","NP_001135969.1//mixed lineage kinase domain-like protein isoform 2 [Homo sapiens];NP_689862.1//mixed lineage kinase domain-like protein isoform 1 [Homo sapiens]","3//A2MP1;2//1"]
[1775,1342,1.07,2.06,0.945033540782071,0.0610200358870968,"*",0.0265258,"DNASE1L2","GO:0005634//nucleus;GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0004536//deoxyribonuclease activity;GO:0005509//calcium ion binding;GO:0004519//endonuclease activity","GO:0003335//corneocyte development;GO:0006308//DNA catabolic process;GO:0001942//hair follicle development;GO:0006259//DNA metabolic process","K11995//deoxyribonuclease-1-like protein [EC:3.1.21.-]","XP_011520701.1//PREDICTED: deoxyribonuclease-1-like 2 isoform X1 [Homo sapiens]","1//3;2//1"]
[1435,3964,23.7,45.6,0.944146765266483,{"v":1.07351773495935E-82,"d":"1.07E-82"},"*",{"v":8.2661e-85,"d":"8.27E-85"},"CSF1","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0048471//perinuclear region of cytoplasm;GO:1990682//CSF1-CSF1R complex","GO:0008083//growth factor activity;GO:0005157//macrophage colony-stimulating factor receptor binding;GO:0005125//cytokine activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity","GO:0043687//post-translational protein modification;GO:0010744//positive regulation of macrophage derived foam cell differentiation;GO:0002158//osteoclast proliferation;GO:0030335//positive regulation of cell migration;GO:0032270//positive regulation of cellular protein metabolic process;GO:0030316//osteoclast differentiation;GO:1902228//positive regulation of macrophage colony-stimulating factor signaling pathway;GO:0045672//positive regulation of osteoclast differentiation;GO:1904141//positive regulation of microglial cell migration;GO:0060444//branching involved in mammary gland duct morphogenesis;GO:0044267//cellular protein metabolic process;GO:0060611//mammary gland fat development;GO:0042488//positive regulation of odontogenesis of dentin-containing tooth;GO:0045651//positive regulation of macrophage differentiation;GO:0038145//macrophage colony-stimulating factor signaling pathway;GO:0045087//innate immune response;GO:0030154//cell differentiation;GO:0032946//positive regulation of mononuclear cell proliferation;GO:0010628//positive regulation of gene expression;GO:0060763//mammary duct terminal end bud growth;GO:0001954//positive regulation of cell-matrix adhesion;GO:0003006//developmental process involved in reproduction;GO:0010759//positive regulation of macrophage chemotaxis;GO:0048873//homeostasis of number of cells within a tissue;GO:0010743//regulation of macrophage derived foam cell differentiation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0046579//positive regulation of Ras protein signal transduction;GO:0008283//cell proliferation;GO:0030225//macrophage differentiation;GO:0045860//positive regulation of protein kinase activity;GO:0030097//hemopoiesis;GO:0030278//regulation of ossification;GO:0006954//inflammatory response;GO:0045657//positive regulation of monocyte differentiation;GO:0040018//positive regulation of multicellular organism growth;GO:0042117//monocyte activation;GO:0008284//positive regulation of cell proliferation","K05453//macrophage colony-stimulating factor 1","EAW56418.1//colony stimulating factor 1 (macrophage), isoform CRA_c [Homo sapiens];EAW56417.1//colony stimulating factor 1 (macrophage), isoform CRA_b [Homo sapiens];EAW56421.1//colony stimulating factor 1 (macrophage), isoform CRA_e [Homo sapiens]","3//A2MP1;2//1;5"]
[388284,1287,0.13,0.25,0.943416471633632,0.609297855380976,"*",0.451538,"C16orf86","NA","NA","NA","K06236//collagen, type I, alpha","NP_001013002.2//uncharacterized protein C16orf86 [Homo sapiens]","2//1"]
[360200,3365,0.26,0.5,0.943416471633632,0.15496130246233,"*",0.079188,"TMPRSS9","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane","GO:0004252//serine-type endopeptidase activity","NA","K09640//transmembrane protease serine 9 [EC:3.4.21.-]","NP_892018.1//transmembrane protease serine 9 [Homo sapiens]","2//1"]
[134701,674,0.13,0.25,0.943416471633632,0.732717062821833,"*",0.623548,"RIPPLY2","GO:0005634//nucleus","NA","GO:0010468//regulation of gene expression;GO:0032525//somite rostral/caudal axis specification;GO:0007368//determination of left/right symmetry;GO:0060349//bone morphogenesis;GO:0001503//ossification;GO:0036342//post-anal tail morphogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0009880//embryonic pattern specification;GO:0001756//somitogenesis;GO:0007219//Notch signaling pathway","NA","XP_008967706.1//PREDICTED: protein ripply2 [Pan paniscus]","2//1"]
[9220,2110,7.57,14.53,0.940669497647109,{"v":2.13869547111111e-13,"d":"2.14E-13"},"*",{"v":1.686964E-14,"d":"1.69E-14"},"TIAF1","GO:0005634//nucleus","NA","GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0043066//negative regulation of apoptotic process;GO:0006915//apoptotic process","K10362//myosin XVIII","NP_004731.2//TGFB1-induced anti-apoptotic factor 1 [Homo sapiens]","3//A2MP1"]
[388701,720,0.12,0.23,0.938599455335857,0.735530627086103,"*",0.623548,"C1orf189","NA","NA","NA","NA","XP_001140210.3//PREDICTED: uncharacterized protein C1orf189 homolog [Pan troglodytes]","2//1"]
[3760,4523,0.12,0.23,0.938599455335857,0.285714328398792,"*",0.1657694,"KCNJ3","GO:0030315//T-tubule;GO:0009897//external side of plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex","GO:0086089//voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization;GO:0005242//inward rectifier potassium channel activity;GO:0015467//G-protein activated inward rectifier potassium channel activity;GO:1902282//voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization","GO:0051602//response to electrical stimulus;GO:0006813//potassium ion transport;GO:0099625//ventricular cardiac muscle cell membrane repolarization;GO:0086091//regulation of heart rate by cardiac conduction;GO:0098914//membrane repolarization during atrial cardiac muscle cell action potential;GO:1990573//potassium ion import across plasma membrane;GO:0010107//potassium ion import","K04997//potassium inwardly-rectifying channel subfamily J member 3","OWK00154.1//hypothetical protein Celaphus_00015869 [Cervus elaphus hippelaphus];XP_002918768.1//PREDICTED: G protein-activated inward rectifier potassium channel 1 isoform X1 [Ailuropoda melanoleuca];NP_002230.1//G protein-activated inward rectifier potassium channel 1 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[91977,3493,0.12,0.23,0.938599455335857,0.344537190161224,"*",0.208698,"MYOZ3","GO:0030018//Z disc;GO:0015629//actin cytoskeleton","GO:0003779//actin binding;GO:0051373//FATZ binding;GO:0031433//telethonin binding","GO:0030239//myofibril assembly","K02927//large subunit ribosomal protein L40e;K15696//RING finger protein 113B;K17985//activating molecule in BECN1-regulated autophagy protein 1","NP_588612.2//myozenin-3 [Homo sapiens]","4;2//1"]
[9074,1389,0.12,0.23,0.938599455335857,0.608937780666948,"*",0.451538,"CLDN6","GO:0016327//apicolateral plasma membrane;GO:0016021//integral component of membrane;GO:0005923//bicellular tight junction;GO:0005886//plasma membrane","GO:0042802//identical protein binding;GO:0005198//structural molecule activity;GO:0001618//virus receptor activity","GO:0045216//cell-cell junction organization;GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules","K06087//claudin","XP_021787371.1//claudin-6 [Papio anubis]",4]
[100130827,1270,1.54,2.95,0.937784603554302,0.0220021302968338,"*",0.00835238,"SBK3","NA","GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding","NA","K08858//serine/threonine-protein kinase SBK [EC:2.7.11.1]","NP_001186753.1//uncharacterized serine/threonine-protein kinase SBK3 [Homo sapiens]","2//1"]
[5359,2228,12.47,23.86,0.936132577865558,{"v":1.68366452265023e-22,"d":"1.68E-22"},"*",{"v":6.84048e-24,"d":"6.84E-24"},"PLSCR1","GO:0016020//membrane;GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005887//integral component of plasma membrane;GO:0045121//membrane raft;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane","GO:0003677//DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0005154//epidermal growth factor receptor binding;GO:0042609//CD4 receptor binding;GO:0005509//calcium ion binding;GO:0017128//phospholipid scramblase activity;GO:0017124//SH3 domain binding;GO:0019899//enzyme binding","GO:0035456//response to interferon-beta;GO:0017121//phospholipid scrambling;GO:0045089//positive regulation of innate immune response;GO:0051607//defense response to virus;GO:0006953//acute-phase response;GO:0030168//platelet activation;GO:0010628//positive regulation of gene expression;GO:0006915//apoptotic process;GO:0033003//regulation of mast cell activation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045071//negative regulation of viral genome replication;GO:0006659//phosphatidylserine biosynthetic process;GO:2000373//positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity;GO:0060368//regulation of Fc receptor mediated stimulatory signaling pathway","K06831//galectin-3","NP_066928.1//phospholipid scramblase 1 [Homo sapiens]","2//1"]
[57480,5899,0.34,0.65,0.934904971778115,0.0390650958889058,"*",0.01602564,"PLEKHG1","NA","NA","NA","K20685//guanine nucleotide exchange factor MCF2;K16463//centrosomal protein CEP170;K09610//endothelin-converting enzyme-like 1 [EC:3.4.24.-]","NP_001316727.1//pleckstrin homology domain-containing family G member 1 isoform a [Homo sapiens];XP_011534284.1//PREDICTED: pleckstrin homology domain-containing family G member 1 isoform X3 [Homo sapiens];NP_001316728.1//pleckstrin homology domain-containing family G member 1 isoform b [Homo sapiens];XP_011534283.1//PREDICTED: pleckstrin homology domain-containing family G member 1 isoform X1 [Homo sapiens]","1//3;2//1"]
[440498,766,13.44,25.66,0.932988032310922,{"v":1.72624422529833e-08,"d":"1.73E-08"},"*",{"v":2.26398e-09,"d":"2.26E-09"},"HSBP1L1","NA","GO:0003714//transcription corepressor activity","NA","K19765//heat shock factor-binding protein 1","NP_001129652.1//heat shock factor-binding protein 1-like protein 1 [Homo sapiens]","1//3"]
[1346,783,0.11,0.21,0.932885804141463,0.732932726416483,"*",0.623548,"COX7A1","NA","NA","NA","K02270//cytochrome c oxidase subunit 7a","XP_010367112.1//PREDICTED: uncharacterized protein LOC104666684 [Rhinopithecus roxellana]","3//A2MP1"]
[7805,2240,0.11,0.21,0.932885804141463,0.495802588534107,"*",0.342164,"LAPTM5","GO:0005765//lysosomal membrane;GO:0005887//integral component of plasma membrane;GO:0005764//lysosome","NA","GO:0006810//transport;GO:1990830//cellular response to leukemia inhibitory factor","K12387//lysosomal-associated transmembrane protein","NP_006753.1//lysosomal-associated transmembrane protein 5 [Homo sapiens]","2//1"]
[25907,1876,9.43,18,0.932667230541941,{"v":1.87138648904228e-14,"d":"1.87E-14"},"*",{"v":1.357792E-15,"d":"1.36E-15"},"TMEM158","GO:0016021//integral component of membrane","GO:0042277//peptide binding","NA","K05746//enabled","NP_056259.2//transmembrane protein 158 precursor [Homo sapiens]","2//1"]
[84125,5460,0.1,0.19,0.925999418556223,0.315428033950358,"*",0.1877482,"LRRIQ1","NA","NA","NA","K12484//Rab11 family-interacting protein 1/2/5;K18626//trichohyalin","NP_001073379.1//leucine-rich repeat and IQ domain-containing protein 1 [Homo sapiens]","1//3"]
[79722,2502,0.1,0.19,0.925999418556223,0.495982553176044,"*",0.342164,"ANKRD55","NA","NA","NA","K19626//inversin","NP_078945.2//ankyrin repeat domain-containing protein 55 [Homo sapiens]","2//1"]
[146310,855,0.1,0.19,0.925999418556223,0.732770966821158,"*",0.623548,"RNF151","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0008270//zinc ion binding","GO:0030154//cell differentiation;GO:0007283//spermatogenesis","K11981//E3 ubiquitin-protein ligase NRDP1 [EC:2.3.2.27];K14555//U3 small nucleolar RNA-associated protein 13","NP_777563.2//RING finger protein 151 isoform 1 [Homo sapiens]","1//3;5"]
[285498,2367,0.37,0.7,0.919829651316017,0.595989831407206,"*",0.439064,"RNF212","GO:0000795//synaptonemal complex","GO:0046872//metal ion binding;GO:0019789//SUMO transferase activity;GO:0016874//ligase activity","GO:0007129//synapsis;GO:0006311//meiotic gene conversion;GO:0016925//protein sumoylation;GO:0007131//reciprocal meiotic recombination;GO:0051026//chiasma assembly","NA","NP_001180247.1//probable E3 SUMO-protein ligase RNF212 isoform c [Homo sapiens];NP_919420.1//probable E3 SUMO-protein ligase RNF212 isoform b [Homo sapiens];NP_001124506.1//probable E3 SUMO-protein ligase RNF212 isoform a [Homo sapiens]","4;3//A2MP1;2//1"]
[90353,2107,6.66,12.59,0.918684200647754,{"v":2.61967223153693e-11,"d":"2.62E-11"},"*",{"v":2.46486e-12,"d":"2.46E-12"},"CTU1","GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005737//cytoplasm","GO:0016779//nucleotidyltransferase activity;GO:0000049//tRNA binding;GO:0016740//transferase activity","GO:0002098//tRNA wobble uridine modification;GO:0032447//protein urmylation;GO:0034227//tRNA thio-modification;GO:0006400//tRNA modification","K14168//cytoplasmic tRNA 2-thiolation protein 1 [EC:2.7.7.-]","XP_014979908.1//PREDICTED: cytoplasmic tRNA 2-thiolation protein 1 isoform X1 [Macaca mulatta]","3//A2MP1"]
[50939,8365,0.09,0.17,0.917537839808027,0.221436758160339,"*",0.1208656,"IMPG2","GO:0033165//interphotoreceptor matrix;GO:0016021//integral component of membrane;GO:0043235//receptor complex;GO:0005578//proteinaceous extracellular matrix","GO:0005201//extracellular matrix structural constituent;GO:0008201//heparin binding;GO:0005540//hyaluronic acid binding","GO:0007601//visual perception","K19017//interphotoreceptor matrix proteoglycan 2","NP_057331.2//interphotoreceptor matrix proteoglycan 2 precursor [Homo sapiens]","3//A2MP1"]
[26257,1890,0.72,1.36,0.917537839808027,0.0724817724244554,"*",0.0322842,"NKX2-8","GO:0005634//nucleus","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0003690//double-stranded DNA binding","GO:0030324//lung development;GO:0001889//liver development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0050680//negative regulation of epithelial cell proliferation;GO:0006351//transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter;GO:0007409//axonogenesis","K09347//homeobox protein Nkx-2.8","NP_055175.2//homeobox protein Nkx-2.8 [Homo sapiens]","3//A2MP1"]
[51660,977,2.28,4.3,0.915302835424718,0.01730617847981,"*",0.00638554,"MPC1","GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0031305//integral component of mitochondrial inner membrane","GO:0050833//pyruvate transmembrane transporter activity","GO:1990830//cellular response to leukemia inhibitory factor;GO:0061732//mitochondrial acetyl-CoA biosynthetic process from pyruvate","K22138//mitochondrial pyruvate carrier 1","NP_057182.1//mitochondrial pyruvate carrier 1 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[9080,2139,0.26,0.49,0.914270125974116,0.315461212453981,"*",0.1877482,"CLDN9","GO:0016021//integral component of membrane;GO:0005923//bicellular tight junction;GO:0005886//plasma membrane","GO:0005198//structural molecule activity","NA","K06087//claudin","XP_008694995.1//PREDICTED: claudin-9 [Ursus maritimus]","3//A2MP1"]
[861,6768,4.06,7.62,0.908311270308146,{"v":1.45498722333722E-18,"d":"1.45E-18"},"*",{"v":7.80596e-20,"d":"7.81E-20"},"RUNX1","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0005524//ATP binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0005509//calcium ion binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0008134//transcription factor binding;GO:0003700//DNA binding transcription factor activity;GO:0001047//core promoter binding","GO:2000810//regulation of bicellular tight junction assembly;GO:0030099//myeloid cell differentiation;GO:0048935//peripheral nervous system neuron development;GO:0001503//ossification;GO:0045637//regulation of myeloid cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0001959//regulation of cytokine-mediated signaling pathway;GO:0030853//negative regulation of granulocyte differentiation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0032743//positive regulation of interleukin-2 production;GO:0071425//hematopoietic stem cell proliferation;GO:0050855//regulation of B cell receptor signaling pathway;GO:0045766//positive regulation of angiogenesis;GO:0030097//hemopoiesis;GO:0030182//neuron differentiation;GO:0006351//transcription, DNA-templated;GO:0030111//regulation of Wnt signaling pathway;GO:0033146//regulation of intracellular estrogen receptor signaling pathway;GO:0030854//positive regulation of granulocyte differentiation;GO:0045652//regulation of megakaryocyte differentiation;GO:0045616//regulation of keratinocyte differentiation;GO:0002062//chondrocyte differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:1902036//regulation of hematopoietic stem cell differentiation;GO:0045595//regulation of cell differentiation;GO:0045589//regulation of regulatory T cell differentiation","K08367//runt-related transcription factor 1","NP_001745.2//runt-related transcription factor 1 isoform AML1c [Homo sapiens];CAA56092.1//acute myeloid leukemia gene no 1 [Homo sapiens];NP_001116079.1//runt-related transcription factor 1 isoform AML1a [Homo sapiens]","4;1//3;2//1"]
[6261,15376,0.16,0.3,0.906890595608518,0.0162300542255691,"*",0.00593666,"RYR1","GO:0030315//T-tubule;GO:0005790//smooth endoplasmic reticulum;GO:0070062//extracellular exosome;GO:0031301//integral component of organelle membrane;GO:0005938//cell cortex;GO:0014802//terminal cisterna;GO:1990425//ryanodine receptor complex;GO:0014701//junctional sarcoplasmic reticulum membrane;GO:0030314//junctional membrane complex;GO:0005737//cytoplasm;GO:0016529//sarcoplasmic reticulum;GO:0005887//integral component of plasma membrane;GO:0031674//I band;GO:0033017//sarcoplasmic reticulum membrane;GO:0005886//plasma membrane","GO:0002020//protease binding;GO:0048763//calcium-induced calcium release activity;GO:0005524//ATP binding;GO:0005245//voltage-gated calcium channel activity;GO:0015278//calcium-release channel activity;GO:0005219//ryanodine-sensitive calcium-release channel activity;GO:0005509//calcium ion binding;GO:0005262//calcium channel activity;GO:0005516//calmodulin binding","GO:0014808//release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0043588//skin development;GO:0034220//ion transmembrane transport;GO:0043931//ossification involved in bone maturation;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0071277//cellular response to calcium ion;GO:0031000//response to caffeine;GO:0071313//cellular response to caffeine;GO:1903779//regulation of cardiac conduction;GO:0051289//protein homotetramerization;GO:0006936//muscle contraction;GO:0006816//calcium ion transport;GO:0003151//outflow tract morphogenesis;GO:0048741//skeletal muscle fiber development;GO:0001666//response to hypoxia;GO:0051209//release of sequestered calcium ion into cytosol","K04961//ryanodine receptor 1","NP_001036188.1//ryanodine receptor 1 isoform 2 [Homo sapiens];NP_000531.2//ryanodine receptor 1 isoform 1 [Homo sapiens]","1//3;2//1"]
[56978,3150,0.08,0.15,0.906890595608518,0.666319969782526,"*",0.546646,"PRDM8","NA","NA","NA","K20797//PR domain zinc finger protein 8 [EC:2.1.1.-]","XP_016863957.1//PREDICTED: PR domain zinc finger protein 8 isoform X1 [Homo sapiens]","1//3;3//A2MP1"]
[60489,2529,0.31,0.58,0.903784684740697,0.166995415205529,"*",0.0862158,"APOBEC3G","GO:0030529//intracellular ribonucleoprotein complex;GO:0005829//cytosol;GO:0030895//apolipoprotein B mRNA editing enzyme complex;GO:0000932//P-body;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0047844//deoxycytidine deaminase activity;GO:0008829//dCTP deaminase activity;GO:0042802//identical protein binding;GO:0004126//cytidine deaminase activity;GO:0008270//zinc ion binding;GO:0042803//protein homodimerization activity","GO:0048525//negative regulation of viral process;GO:0051607//defense response to virus;GO:0016032//viral process;GO:0045869//negative regulation of single stranded viral RNA replication via double stranded DNA intermediate;GO:0070383//DNA cytosine deamination;GO:0009972//cytidine deamination;GO:0010529//negative regulation of transposition;GO:0045071//negative regulation of viral genome replication;GO:0045087//innate immune response;GO:0002230//positive regulation of defense response to virus by host;GO:0016553//base conversion or substitution editing","K18750//C->U-editing enzyme APOBEC3 [EC:3.5.4.-]","NP_001336365.1//DNA dC-;NP_001336367.1//DNA dC-;NP_068594.1//DNA dC-","1//3;3//A2MP1"]
[126231,2491,0.44,0.82,0.898120385980786,0.110430474302264,"*",0.0525122,"ZNF573","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","NP_001166161.1//zinc finger protein 573 isoform 3 [Homo sapiens];XP_016881766.1//PREDICTED: zinc finger protein 573 isoform X2 [Homo sapiens];NP_001166162.1//zinc finger protein 573 isoform 4 [Homo sapiens];NP_689573.3//zinc finger protein 573 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[56971,2263,14.85,27.64,0.896294684700131,{"v":1.41047331880492e-24,"d":"1.41E-24"},"*",{"v":5.02416e-26,"d":"5.02E-26"},"CEACAM19","GO:0016021//integral component of membrane","NA","NA","K16825//carcinoembryonic antigen-related cell adhesion molecule 19","NP_064604.2//carcinoembryonic antigen-related cell adhesion molecule 19 isoform 2 precursor [Homo sapiens];NP_001121365.1//carcinoembryonic antigen-related cell adhesion molecule 19 isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[6515,3938,5.49,10.2,0.893691097853659,{"v":3.68483654563297e-16,"d":"3.68E-16"},"*",{"v":2.3506e-17,"d":"2.35E-17"},"SLC2A3","GO:0016021//integral component of membrane","GO:0005355//glucose transmembrane transporter activity","NA","K08142//MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 3","XP_002752353.3//PREDICTED: solute carrier family 2, facilitated glucose transporter member 3 [Callithrix jacchus]","2//1"]
[80853,9178,0.21,0.39,0.893084796083488,0.0403349445055446,"*",0.01662232,"KDM7A","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus","GO:0035575//histone demethylase activity (H4-K20 specific);GO:0005506//iron ion binding;GO:0035064//methylated histone binding;GO:0032452//histone demethylase activity;GO:0051864//histone demethylase activity (H3-K36 specific);GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;GO:0008270//zinc ion binding;GO:0032454//histone demethylase activity (H3-K9 specific);GO:0071558//histone demethylase activity (H3-K27 specific)","GO:0030901//midbrain development;GO:0035574//histone H4-K20 demethylation;GO:0033169//histone H3-K9 demethylation;GO:0071557//histone H3-K27 demethylation;GO:0006351//transcription, DNA-templated;GO:0070544//histone H3-K36 demethylation;GO:0045893//positive regulation of transcription, DNA-templated","K11445//lysine-specific demethylase 7A [EC:1.14.11.-]","NP_085150.1//lysine-specific demethylase 7A [Homo sapiens]","1//3"]
[100820829,2355,0.28,0.52,0.893084796083488,0.262596199715505,"*",0.1502358,"MYZAP","GO:0005622//intracellular","NA","GO:0035556//intracellular signal transduction","K22031//myocardial zonula adherens protein","NP_689664.3//myocardial zonula adherens protein isoform 2 [Homo sapiens];XP_012298454.1//myocardial zonula adherens protein isoform X1 [Aotus nancymaae]","4;7"]
[100288695,1221,0.07,0.13,0.893084796083488,0.732986662153212,"*",0.623548,"LIMS4","GO:0005737//cytoplasm","GO:0046872//metal ion binding","NA","NA","NP_277049.1//LIM and senescent cell antigen-like-containing domain protein 3 [Homo sapiens]","1//3"]
[57576,4000,0.28,0.52,0.893084796083488,0.121596952474734,"*",0.0587508,"KIF17","GO:0030992//intraciliary transport particle B;GO:0005929//cilium;GO:0032839//dendrite cytoplasm;GO:0005874//microtubule;GO:0032391//photoreceptor connecting cilium;GO:0036064//ciliary basal body;GO:1990075//periciliary membrane compartment;GO:0005829//cytosol;GO:0005930//axoneme;GO:0005871//kinesin complex","GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0008574//ATP-dependent microtubule motor activity, plus-end-directed","GO:0022008//neurogenesis;GO:0007018//microtubule-based movement;GO:0035735//intraciliary transport involved in cilium assembly;GO:0098971//anterograde dendritic transport of neurotransmitter receptor complex;GO:0030030//cell projection organization;GO:0016192//vesicle-mediated transport","K20198//kinesin family member 17","NP_065867.2//kinesin-like protein KIF17 isoform a [Homo sapiens];NP_001116291.1//kinesin-like protein KIF17 isoform b [Homo sapiens]","1//3;3//A2MP1;2//1"]
[25819,1984,6.33,11.74,0.891155003681711,{"v":1.30972932461538E-9,"d":"1.31E-09"},"*",{"v":1.492242E-10,"d":"1.49E-10"},"NOCT","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000932//P-body;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm","GO:0004535//poly(A)-specific ribonuclease activity;GO:0003729//mRNA binding;GO:0046872//metal ion binding;GO:0003700//DNA binding transcription factor activity","GO:0006397//mRNA processing;GO:0007623//circadian rhythm;GO:0009991//response to extracellular stimulus;GO:0045995//regulation of embryonic development;GO:0045600//positive regulation of fat cell differentiation;GO:0032496//response to lipopolysaccharide;GO:0010629//negative regulation of gene expression;GO:0000290//deadenylation-dependent decapping of nuclear-transcribed mRNA;GO:0006366//transcription from RNA polymerase II promoter;GO:0042752//regulation of circadian rhythm;GO:0045668//negative regulation of osteoblast differentiation;GO:0033962//cytoplasmic mRNA processing body assembly;GO:0032922//circadian regulation of gene expression;GO:0048255//mRNA stabilization","K18764//nocturnin [EC:3.1.13.4]","NP_036250.2//nocturnin [Homo sapiens]","3//A2MP1"]
[80741,738,0.8,1.48,0.887525270741587,0.31536169787592,"*",0.1877482,"LY6G5C","GO:0009897//external side of plasma membrane;GO:0043234//protein complex;GO:0016021//integral component of membrane;GO:0005576//extracellular region","GO:0042802//identical protein binding","GO:0051260//protein homooligomerization","K20005//lymphocyte antigen 6 complex locus protein G5","NP_079538.3//lymphocyte antigen 6 complex locus protein G5c precursor [Homo sapiens]","3//A2MP1"]
[2826,1244,0.46,0.85,0.885828980080689,0.315394862425071,"*",0.1877482,"CCR10","GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0016493//C-C chemokine receptor activity;GO:0004930//G-protein coupled receptor activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0006955//immune response;GO:0006935//chemotaxis","K04185//C-C chemokine receptor type 10","NP_057686.2//C-C chemokine receptor type 10 [Homo sapiens]","2//1"]
[389692,2373,0.13,0.24,0.884522782580064,0.540203744762906,"*",0.385826,"MAFA","GO:0005634//nucleus","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0009749//response to glucose;GO:0007263//nitric oxide mediated signal transduction;GO:0030073//insulin secretion;GO:0045893//positive regulation of transcription, DNA-templated","K21125//mucin-5AC","NP_919331.1//transcription factor MafA [Mus musculus]","3//A2MP1"]
[147746,2501,0.26,0.48,0.884522782580064,0.262624936441234,"*",0.1502358,"HIPK4","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity","GO:1901796//regulation of signal transduction by p53 class mediator;GO:0018105//peptidyl-serine phosphorylation;GO:0016572//histone phosphorylation;GO:0046777//protein autophosphorylation","K08826//homeodomain interacting protein kinase [EC:2.7.11.1]","NP_653286.2//homeodomain-interacting protein kinase 4 [Homo sapiens]",4]
[196051,1354,0.13,0.24,0.884522782580064,0.608834980332574,"*",0.451538,"PLPP4","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0042802//identical protein binding;GO:0008195//phosphatidate phosphatase activity","GO:0007165//signal transduction;GO:0046839//phospholipid dephosphorylation;GO:0006644//phospholipid metabolic process;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis","K18693//diacylglycerol diphosphate phosphatase / phosphatidate phosphatase [EC:3.1.3.81 3.1.3.4]","NP_001305098.1//phospholipid phosphatase 4 isoform e [Homo sapiens];NP_001305095.1//phospholipid phosphatase 4 isoform b [Homo sapiens];XP_001496078.4//PREDICTED: phosphatidate phosphatase PPAPDC1A [Equus caballus];XP_010363972.1//PREDICTED: phosphatidate phosphatase PPAPDC1A [Rhinopithecus roxellana];NP_001305096.1//phospholipid phosphatase 4 isoform c [Homo sapiens]","1//3;2//1"]
[1890,1714,8.56,15.8,0.884241856663318,{"v":9.81489489265537e-11,"d":"9.81E-11"},"*",{"v":9.78786e-12,"d":"9.79E-12"},"TYMP","GO:0005829//cytosol","GO:0016763//transferase activity, transferring pentosyl groups;GO:0016154//pyrimidine-nucleoside phosphorylase activity;GO:0008083//growth factor activity;GO:0009032//thymidine phosphorylase activity;GO:0042803//protein homodimerization activity;GO:0004645//phosphorylase activity","GO:0051969//regulation of transmission of nerve impulse;GO:0046135//pyrimidine nucleoside catabolic process;GO:0030154//cell differentiation;GO:0001525//angiogenesis;GO:0031641//regulation of myelination;GO:0043097//pyrimidine nucleoside salvage;GO:0006213//pyrimidine nucleoside metabolic process;GO:1905333//regulation of gastric motility;GO:0000002//mitochondrial genome maintenance;GO:0006935//chemotaxis;GO:0006206//pyrimidine nucleobase metabolic process","K00758//thymidine phosphorylase [EC:2.4.2.4]","XP_017360425.1//PREDICTED: thymidine phosphorylase isoform X2 [Cebus capucinus imitator];NP_001944.1//thymidine phosphorylase isoform 1 precursor [Homo sapiens];NP_001244918.1//thymidine phosphorylase isoform 2 [Homo sapiens]","4;1//3;2//1"]
[5329,1554,19.23,35.45,0.882426864786981,{"v":2.17896830691489e-20,"d":"2.18E-20"},"*",{"v":1.025782e-21,"d":"1.03E-21"},"PLAUR","GO:0070062//extracellular exosome;GO:0005788//endoplasmic reticulum lumen;GO:0005925//focal adhesion;GO:0019898//extrinsic component of membrane;GO:0030054//cell junction;GO:0031225//anchored component of membrane;GO:0071438//invadopodium membrane;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0035579//specific granule membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane","GO:0019904//protein domain specific binding;GO:0004872//receptor activity;GO:0030377//urokinase plasminogen activator receptor activity;GO:0005102//receptor binding;GO:0019899//enzyme binding","GO:0042730//fibrinolysis;GO:0007165//signal transduction;GO:0007596//blood coagulation;GO:0038195//urokinase plasminogen activator signaling pathway;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway;GO:2001268//negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0016255//attachment of GPI anchor to protein;GO:0006928//movement of cell or subcellular component;GO:0030162//regulation of proteolysis;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0001934//positive regulation of protein phosphorylation;GO:0043312//neutrophil degranulation;GO:0045742//positive regulation of epidermal growth factor receptor signaling pathway;GO:0006935//chemotaxis;GO:0043388//positive regulation of DNA binding","K03985//plasminogen activator, urokinase receptor","NP_001005377.1//urokinase plasminogen activator surface receptor isoform 3 precursor [Homo sapiens];NP_001287966.1//urokinase plasminogen activator surface receptor isoform 4 precursor [Homo sapiens];NP_002650.1//urokinase plasminogen activator surface receptor isoform 1 precursor [Homo sapiens];NP_001005376.1//urokinase plasminogen activator surface receptor isoform 2 precursor [Homo sapiens]","1//3;3//A2MP1;2//1"]
[115361,6160,0.83,1.53,0.882348411345727,0.000244843879281558,"*",{"v":6.05902e-05,"d":"6.06E-05"},"GBP4","GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0000139//Golgi membrane","GO:0005525//GTP binding;GO:0003924//GTPase activity","NA","K20899//guanylate-binding protein 1/3/4/7","NP_443173.2//guanylate-binding protein 4 [Homo sapiens]",4]
[10906,2753,11.14,20.53,0.88198439476857,{"v":1.76706045244957e-21,"d":"1.77E-21"},"*",{"v":7.6771e-23,"d":"7.68E-23"},"TRAFD1","NA","GO:0046872//metal ion binding","GO:0045824//negative regulation of innate immune response;GO:0034097//response to cytokine","NA","NP_006691.1//TRAF-type zinc finger domain-containing protein 1 [Homo sapiens]","1//3;2//1"]
[161582,1811,9.69,17.85,0.881355503501381,{"v":1.43423598727811e-12,"d":"1.43E-12"},"*",{"v":1.213902e-13,"d":"1.21E-13"},"DNAAF4","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005813//centrosome;GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0097730//non-motile cilium","GO:0030331//estrogen receptor binding","GO:0003341//cilium movement;GO:0001764//neuron migration;GO:0007368//determination of left/right symmetry;GO:0036159//inner dynein arm assembly;GO:0033146//regulation of intracellular estrogen receptor signaling pathway;GO:0036158//outer dynein arm assembly;GO:0061136//regulation of proteasomal protein catabolic process","K19758//dyslexia susceptibility 1 candidate gene 1 protein","XP_011948424.1//PREDICTED: dyslexia susceptibility 1 candidate gene 1 protein isoform X1 [Cercocebus atys];XP_010370873.1//PREDICTED: dyslexia susceptibility 1 candidate gene 1 protein isoform X3 [Rhinopithecus roxellana];XP_010370872.1//PREDICTED: dyslexia susceptibility 1 candidate gene 1 protein isoform X2 [Rhinopithecus roxellana]","1//3;3//A2MP1;2//1"]
[163154,1407,6.17,11.36,0.880620440355264,{"v":1.14172853701493e-06,"d":"1.14E-06"},"*",{"v":1.915508e-07,"d":"1.92E-07"},"PRR22","NA","NA","NA","K19719//collagen, type II, alpha;K16483//centrosomal protein POC5;K05544//tRNA-dihydrouridine synthase 3 [EC:1.3.1.89];K19720//collagen, type III, alpha","XP_004059883.2//PREDICTED: proline-rich protein 22 [Gorilla gorilla gorilla]","1//3"]
[10437,1034,20.28,37.2,0.875244968992053,{"v":1.71814245427831E-14,"d":"1.72E-14"},"*",{"v":1.244454E-15,"d":"1.24E-15"},"IFI30","GO:0043231//intracellular membrane-bounded organelle;GO:0005829//cytosol;GO:0043202//lysosomal lumen;GO:0005576//extracellular region;GO:0030054//cell junction;GO:0005764//lysosome","GO:0016667//oxidoreductase activity, acting on a sulfur group of donors","GO:0060333//interferon-gamma-mediated signaling pathway;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II","K08059//interferon, gamma-inducible protein 30","AAF04618.1//gamma-interferon inducible lysosomal thiol reductase [Homo sapiens]",4]
[22987,7442,0.36,0.66,0.874469117916141,0.955412686238532,"*",0.912708,"SV2C","GO:0008021//synaptic vesicle;GO:0016021//integral component of membrane","GO:0022857//transmembrane transporter activity","NA","K06258//MFS transporter, VNT family, synaptic vesicle glycoprotein 2","XP_008961059.1//PREDICTED: synaptic vesicle glycoprotein 2C isoform X2 [Pan paniscus];XP_011944649.1//PREDICTED: synaptic vesicle glycoprotein 2C isoform X1 [Cercocebus atys]","1//3;3//A2MP1"]
[392255,3714,0.06,0.11,0.874469117916141,0.629341514835293,"*",0.505908,"GDF6","GO:0005615//extracellular space;GO:0005576//extracellular region","GO:0008083//growth factor activity;GO:0005125//cytokine activity;GO:0005160//transforming growth factor beta receptor binding;GO:0042803//protein homodimerization activity","GO:0045666//positive regulation of neuron differentiation;GO:0043408//regulation of MAPK cascade;GO:0030509//BMP signaling pathway;GO:0032924//activin receptor signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0032332//positive regulation of chondrocyte differentiation;GO:0006915//apoptotic process;GO:0060395//SMAD protein signal transduction;GO:1900745//positive regulation of p38MAPK cascade;GO:1990009//retinal cell apoptotic process;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0045444//fat cell differentiation;GO:0060389//pathway-restricted SMAD protein phosphorylation;GO:0042981//regulation of apoptotic process;GO:0048468//cell development","K20012//growth differentiation factor 6","NP_001001557.1//growth/differentiation factor 6 preproprotein [Homo sapiens]","3//A2MP1"]
[114900,1436,0.06,0.11,0.874469117916141,0.735747950361944,"*",0.623548,"C1QTNF4","NA","NA","NA","K06237//collagen, type IV, alpha;K13172//serine/arginine repetitive matrix protein 2","XP_007997484.1//PREDICTED: complement C1q tumor necrosis factor-related protein 4 [Chlorocebus sabaeus]","2//1"]
[57699,1818,0.06,0.11,0.874469117916141,0.732950721160185,"*",0.626454,"CPNE5","GO:0070062//extracellular exosome;GO:0043025//neuronal cell body;GO:0043204//perikaryon;GO:0043005//neuron projection","NA","GO:1903861//positive regulation of dendrite extension","K16280//E3 ubiquitin-protein ligase RGLG [EC:2.3.2.27];K11348//bromodomain and PHD finger-containing protein 1;K20493//leucine-rich repeat-containing protein 16","XP_018885026.1//PREDICTED: copine-5 isoform X3 [Gorilla gorilla gorilla];XP_016008139.1//PREDICTED: copine-5 isoform X13 [Rousettus aegyptiacus];NP_065990.1//copine-5 isoform a [Homo sapiens]","1//3"]
[326340,1467,0.06,0.11,0.874469117916141,0.734500092323575,"*",0.623548,"ZAR1","GO:0005737//cytoplasm","NA","GO:0007275//multicellular organism development","K18762//zygote arrest protein 1","NP_783318.1//zygote arrest protein 1 [Homo sapiens]","2//1"]
[9715,4285,0.06,0.11,0.874469117916141,0.495847567449878,"*",0.342164,"FAM131B","GO:0005654//nucleoplasm;GO:0005829//cytosol","NA","NA","K03260//translation initiation factor 4G;K05010//chloride channel 1, skeletal muscle","NP_001026860.2//protein FAM131B isoform a [Homo sapiens]","1//3;4;2//1"]
[55337,2147,8.15,14.94,0.874308183670797,{"v":1.69216810411765e-12,"d":"1.69E-12"},"*",{"v":1.440684E-13,"d":"1.44E-13"},"C19orf66","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0003723//RNA binding","GO:0034340//response to type I interferon;GO:0034341//response to interferon-gamma;GO:0045071//negative regulation of viral genome replication;GO:0034342//response to type III interferon;GO:0051607//defense response to virus","K07603//collagen, type XVII, alpha;K06274//vasodilator-stimulated phosphoprotein","NP_060851.2//repressor of yield of DENV protein isoform 1 [Homo sapiens];NP_001295206.1//repressor of yield of DENV protein isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[6339,3063,0.88,1.61,0.87148525947732,0.0116542848318804,"*",0.00410096,"SCNN1D","GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0015629//actin cytoskeleton;GO:0005886//plasma membrane","GO:0015280//ligand-gated sodium channel activity","GO:0050909//sensory perception of taste;GO:0034220//ion transmembrane transport;GO:0050896//response to stimulus;GO:0006814//sodium ion transport","K04826//amiloride-sensitive sodium channel subunit delta","NP_001123885.2//amiloride-sensitive sodium channel subunit delta [Homo sapiens]","3//A2MP1"]
[56114,4602,0.17,0.31,0.866733469136536,0.240106335,"*",0.1346784,"PCDHGA1","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005509//calcium ion binding","GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules","K16495//protocadherin gamma subfamily A","XP_010336467.1//PREDICTED: protocadherin gamma-A1 isoform X9 [Saimiri boliviensis boliviensis];XP_002816053.1//PREDICTED: protocadherin gamma-A1 [Pongo abelii]","1//3;2//1"]
[283869,1033,0.96,1.75,0.866248611111173,0.170587200338042,"*",0.0884546,"NPW","NA","NA","NA","K20655//Rho GTPase-activating protein SYDE;K19475//WAS/WASL-interacting protein;K05267//preproneuropeptide B","EAW85567.1//hCG1817523, isoform CRA_a, partial [Homo sapiens]","2//1"]
[83858,2530,1.87,3.4,0.862496476250065,0.000769019891000687,"*",0.000210236,"ATAD3B","GO:0030667//secretory granule membrane;GO:0101003//ficolin-1-rich granule membrane;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0005886//plasma membrane","GO:0005524//ATP binding","GO:0043312//neutrophil degranulation","K17681//ATPase family AAA domain-containing protein 3A/B","NP_114127.3//ATPase family AAA domain-containing protein 3B isoform AAA-TOB3l [Homo sapiens];BAA86587.1//KIAA1273 protein, partial [Homo sapiens]","1//3;5"]
[11148,2679,0.66,1.2,0.862496476250065,0.0519436728395062,"*",0.022125,"HHLA2","GO:0016021//integral component of membrane","NA","GO:0031295//T cell costimulation;GO:0001819//positive regulation of cytokine production;GO:0042104//positive regulation of activated T cell proliferation","K06747//immune costimulatory protein B7-H4;K06746//immune costimulatory protein B7-H3","NP_009003.1//HERV-H LTR-associating protein 2 isoform a precursor [Homo sapiens];NP_001269488.1//HERV-H LTR-associating protein 2 isoform c [Homo sapiens];NP_001269487.1//HERV-H LTR-associating protein 2 isoform b precursor [Homo sapiens]","1//3;3//A2MP1"]
[113802,1724,1.51,2.74,0.859627343635448,0.0162328323930161,"*",0.00593666,"HENMT1","GO:0043186//P granule","GO:0003723//RNA binding;GO:0046872//metal ion binding;GO:0008171//O-methyltransferase activity;GO:0008173//RNA methyltransferase activity","GO:0001510//RNA methylation;GO:0031047//gene silencing by RNA;GO:0034587//piRNA metabolic process","K20798//small RNA 2'-O-methyltransferase [EC:2.1.1.-]","XP_015001814.1//PREDICTED: small RNA 2'-O-methyltransferase isoform X1 [Macaca mulatta];NP_653185.2//small RNA 2'-O-methyltransferase [Homo sapiens]","1//3;2//1"]
[266727,8907,2.26,4.1,0.859301137090258,{"v":6.57192393103448e-14,"d":"6.57E-14"},"*",{"v":5.01102e-15,"d":"5.01E-15"},"MDGA1","GO:0016020//membrane;GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0046658//anchored component of plasma membrane;GO:0005886//plasma membrane","NA","GO:0006501//C-terminal protein lipidation;GO:0001764//neuron migration;GO:0007420//brain development;GO:0021527//spinal cord association neuron differentiation","K17341//hemicentin","NP_705691.1//MAM domain-containing glycosylphosphatidylinositol anchor protein 1 preproprotein [Homo sapiens]","3//A2MP1"]
[170961,4041,0.16,0.29,0.857980995127572,0.262653679457152,"*",0.1502358,"ANKRD24","NA","NA","NA","K16628//collagen, type VII, alpha","XP_011526059.1//PREDICTED: ankyrin repeat domain-containing protein 24 isoform X1 [Homo sapiens]","1//3"]
[113278,2716,0.21,0.38,0.855610090664825,0.315328540300704,"*",0.1877482,"SLC52A3","GO:0005887//integral component of plasma membrane;GO:0016324//apical plasma membrane;GO:0005886//plasma membrane","GO:0032217//riboflavin transmembrane transporter activity","GO:0006771//riboflavin metabolic process;GO:0007605//sensory perception of sound;GO:0032218//riboflavin transport;GO:0034605//cellular response to heat","K14620//riboflavin transporter 2","XP_007961150.1//PREDICTED: solute carrier family 52, riboflavin transporter, member 3 isoform X1 [Chlorocebus sabaeus]","3//A2MP1"]
[92840,1553,6.2,11.19,0.851869915702156,{"v":7.20011570844582e-07,"d":"7.20E-07"},"*",{"v":1.168768E-7,"d":"1.17E-07"},"REEP6","GO:0044317//rod spherule;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0001917//photoreceptor inner segment;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0045177//apical part of cell","NA","GO:0032386//regulation of intracellular transport;GO:0050908//detection of light stimulus involved in visual perception","K17279//receptor expression-enhancing protein 5/6","EHH29425.1//hypothetical protein EGK_09851, partial [Macaca mulatta]","3//A2MP1;2//1"]
[5098,2924,3.44,6.2,0.84985965057214,6.202398056926E-3,"*",2.04624E-3,"PCDHGC3","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005509//calcium ion binding","GO:0007399//nervous system development;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007267//cell-cell signaling;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules","K16493//protocadherin alpha;K16496//protocadherin gamma subfamily B;K16497//protocadherin gamma subfamily C;K16495//protocadherin gamma subfamily A","NP_002579.2//protocadherin gamma-C3 isoform 1 precursor [Homo sapiens];NP_115778.1//protocadherin gamma-C3 isoform 2 precursor [Homo sapiens];XP_012360269.1//PREDICTED: protocadherin gamma-B5 isoform X17 [Nomascus leucogenys]","1//3;3//A2MP1;2//1"]
[344658,2387,0.05,0.09,0.84799690655495,0.735856660165485,"*",0.623548,"SAMD7","GO:0005634//nucleus;GO:0005737//cytoplasm","NA","NA","K11457//polyhomeotic-like protein 2","NP_872416.1//sterile alpha motif domain-containing protein 7 [Homo sapiens]","1//3;3//A2MP1"]
[147948,3150,0.1,0.18,0.84799690655495,0.540014415491107,"*",0.385826,"ZNF582","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_012027239.2//PREDICTED: zinc finger protein 582 isoform X2 [Ovis aries musimon];XP_008526872.1//PREDICTED: zinc finger protein 582 isoform X1 [Equus przewalskii]","1//3;2//1"]
[8048,1464,0.05,0.09,0.84799690655495,0.647881759427828,"*",0.499032,"CSRP3","GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0030018//Z disc","GO:0003779//actin binding;GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0008307//structural constituent of muscle;GO:0031433//telethonin binding;GO:0042805//actinin binding","GO:1903919//negative regulation of actin filament severing;GO:0048738//cardiac muscle tissue development;GO:0006351//transcription, DNA-templated;GO:0003300//cardiac muscle hypertrophy;GO:0002026//regulation of the force of heart contraction;GO:0045662//negative regulation of myoblast differentiation;GO:0033365//protein localization to organelle;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0060048//cardiac muscle contraction;GO:0045663//positive regulation of myoblast differentiation;GO:1903920//positive regulation of actin filament severing;GO:0007519//skeletal muscle tissue development;GO:0006874//cellular calcium ion homeostasis;GO:0055003//cardiac myofibril assembly;GO:0035995//detection of muscle stretch","K09377//cysteine and glycine-rich protein","XP_010985770.1//PREDICTED: cysteine and glycine-rich protein 3 isoform X2 [Camelus dromedarius]",4]
[56171,12408,0.05,0.09,0.84799690655495,0.34416949369183,"*",0.208346,"DNAH7","NA","NA","NA","K10408//dynein heavy chain, axonemal","XP_005573852.1//PREDICTED: dynein heavy chain 7, axonemal isoform X1 [Macaca fascicularis]","2//1"]
[11181,1781,0.05,0.09,0.84799690655495,0.732339956767885,"*",0.623548,"TREH","GO:0070062//extracellular exosome;GO:0046658//anchored component of plasma membrane;GO:0005886//plasma membrane","GO:0004555//alpha,alpha-trehalase activity","GO:0009887//animal organ morphogenesis;GO:0005993//trehalose catabolic process;GO:0005991//trehalose metabolic process","K01194//alpha,alpha-trehalase [EC:3.2.1.28]","NP_001287994.1//trehalase isoform 2 precursor [Homo sapiens];NP_009111.2//trehalase isoform 1 precursor [Homo sapiens]","1//3;2//1"]
[3770,2851,0.84,1.51,0.846087316546319,0.0225949421557673,"*",0.00860854,"KCNJ14","GO:0030425//dendrite;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0043025//neuronal cell body","GO:0005242//inward rectifier potassium channel activity","GO:0061337//cardiac conduction;GO:0010107//potassium ion import","K05007//potassium inwardly-rectifying channel subfamily J member 14","NP_037480.1//ATP-sensitive inward rectifier potassium channel 14 [Homo sapiens]","3//A2MP1"]
[4092,2849,12.31,22.07,0.842255867795157,{"v":3.52808633820459e-17,"d":"3.53E-17"},"*",{"v":2.11588e-18,"d":"2.12E-18"},"SMAD7","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005622//intracellular;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0016342//catenin complex;GO:0005913//cell-cell adherens junction;GO:0005667//transcription factor complex;GO:0005829//cytosol;GO:0043234//protein complex;GO:0001650//fibrillar center;GO:0005886//plasma membrane","GO:0030617//transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity;GO:0003677//DNA binding;GO:0048185//activin binding;GO:0031625//ubiquitin protein ligase binding;GO:0044212//transcription regulatory region DNA binding;GO:0046872//metal ion binding;GO:0005518//collagen binding;GO:0070411//I-SMAD binding;GO:0003700//DNA binding transcription factor activity;GO:0034713//type I transforming growth factor beta receptor binding;GO:0008013//beta-catenin binding","GO:0051444//negative regulation of ubiquitin-protein transferase activity;GO:0060412//ventricular septum morphogenesis;GO:0010717//regulation of epithelial to mesenchymal transition;GO:0043433//negative regulation of DNA binding transcription factor activity;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0017015//regulation of transforming growth factor beta receptor signaling pathway;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0016579//protein deubiquitination;GO:0002725//negative regulation of T cell cytokine production;GO:0032925//regulation of activin receptor signaling pathway;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0034629//cellular protein complex localization;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0055117//regulation of cardiac muscle contraction;GO:0030509//BMP signaling pathway;GO:2000320//negative regulation of T-helper 17 cell differentiation;GO:1990830//cellular response to leukemia inhibitory factor;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0060394//negative regulation of pathway-restricted SMAD protein phosphorylation;GO:0010801//negative regulation of peptidyl-threonine phosphorylation;GO:0030514//negative regulation of BMP signaling pathway;GO:0031397//negative regulation of protein ubiquitination;GO:0010944//negative regulation of transcription by competitive promoter binding;GO:0006355//regulation of transcription, DNA-templated;GO:0022409//positive regulation of cell-cell adhesion;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:2000317//negative regulation of T-helper 17 type immune response;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0034616//response to laminar fluid shear stress;GO:0031398//positive regulation of protein ubiquitination;GO:0006351//transcription, DNA-templated;GO:0030336//negative regulation of cell migration;GO:0060373//regulation of ventricular cardiac muscle cell membrane depolarization;GO:0034333//adherens junction assembly;GO:0048844//artery morphogenesis;GO:0060389//pathway-restricted SMAD protein phosphorylation;GO:0001657//ureteric bud development;GO:0050821//protein stabilization","K19631//mothers against decapentaplegic homolog 7","EDL82858.1//MAD homolog 7 (Drosophila), isoform CRA_a [Rattus norvegicus];NP_001177752.1//mothers against decapentaplegic homolog 7 isoform 4 [Homo sapiens];XP_012657553.1//PREDICTED: mothers against decapentaplegic homolog 7 isoform X1 [Otolemur garnettii]","1//3;3//A2MP1"]
[4902,1139,0.72,1.29,0.841302253980942,0.240133135573167,"*",0.1346784,"NRTN","GO:0030424//axon;GO:0005622//intracellular;GO:0005576//extracellular region","GO:0008083//growth factor activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005102//receptor binding","GO:0007399//nervous system development;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0021675//nerve development;GO:0000165//MAPK cascade;GO:0001755//neural crest cell migration;GO:0031175//neuron projection development;GO:0007411//axon guidance","K05452//glial cell derived neurotrophic factor","NP_004549.1//neurturin preproprotein [Homo sapiens]",4]
[414235,2224,0.24,0.43,0.841302253980942,0.402966085529491,"*",0.26132,"PRR26","NA","NA","NA","NA","NP_001342319.1//proline-rich protein 26 isoform 4 [Homo sapiens];NP_001342318.1//proline-rich protein 26 isoform 3 [Homo sapiens];NP_001342317.1//proline-rich protein 26 isoform 2 [Homo sapiens];NP_001342316.1//proline-rich protein 26 isoform 1 [Homo sapiens]","1//3"]
[100462983,1383,4.59,8.22,0.840644240267875,0.000101015251427018,"*",{"v":2.3265e-05,"d":"2.33E-05"},"MTRNR2L3","NA","NA","NA","K22237//Rab effector MyRIP","XP_012365851.1//PREDICTED: rab effector MyRIP [Nomascus leucogenys]","1//3"]
[123264,940,1.67,2.99,0.840297381724053,0.0863985803556772,"*",0.0395376,"SLC51B","NA","NA","NA","K14361//organic solute transporter subunit beta","XP_018866857.1//PREDICTED: organic solute transporter subunit beta isoform X1 [Gorilla gorilla gorilla]","3//A2MP1"]
[4924,2585,83.41,149.29,0.839825268194443,{"v":9.11411617971014e-134,"d":"9.11E-134"},"*",{"v":3.93686E-136,"d":"3.94E-136"},"NUCB1","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005788//endoplasmic reticulum lumen;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0032580//Golgi cisterna membrane;GO:0005791//rough endoplasmic reticulum;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005802//trans-Golgi network;GO:0005801//cis-Golgi network;GO:0005798//Golgi-associated vesicle;GO:0005769//early endosome;GO:0090498//extrinsic component of Golgi membrane;GO:0098547//lumenal side of Golgi membrane","GO:0003677//DNA binding;GO:0001965//G-protein alpha-subunit binding;GO:0005509//calcium ion binding","GO:0043687//post-translational protein modification;GO:0044267//cellular protein metabolic process;GO:0072718//response to cisplatin;GO:1903533//regulation of protein targeting","K20371//nucleobindin","NP_006175.2//nucleobindin-1 precursor [Homo sapiens]",5]
[3959,2277,74.42,132.95,0.837121481619257,{"v":3.86725031724138E-104,"d":"3.87E-104"},"*",{"v":2.10624e-106,"d":"2.11E-106"},"LGALS3BP","GO:0016020//membrane;GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0072562//blood microparticle;GO:0031089//platelet dense granule lumen;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix","GO:0005044//scavenger receptor activity","GO:0002576//platelet degranulation;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0006968//cellular defense response","K17300//galectin-3-binding protein","NP_005558.1//galectin-3-binding protein precursor [Homo sapiens]","3//A2MP1"]
[54739,3487,0.28,0.5,0.836501267717121,0.220278323527385,"*",0.1200954,"XAF1","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005739//mitochondrion","GO:0008270//zinc ion binding","GO:0035456//response to interferon-beta;GO:0060337//type I interferon signaling pathway;GO:0034097//response to cytokine;GO:0031333//negative regulation of protein complex assembly;GO:0006915//apoptotic process","K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K15696//RING finger protein 113B;K01064//wingless-type MMTV integration site family, member 9","NP_001340069.1//XIAP-associated factor 1 isoform 7 [Homo sapiens];NP_001340068.1//XIAP-associated factor 1 isoform 6 [Homo sapiens];XP_005256765.1//PREDICTED: XIAP-associated factor 1 isoform X8 [Homo sapiens];XP_004058479.1//PREDICTED: XIAP-associated factor 1 isoform X5 [Gorilla gorilla gorilla];NP_001340067.1//XIAP-associated factor 1 isoform 5 [Homo sapiens];XP_005256763.1//PREDICTED: XIAP-associated factor 1 isoform X4 [Homo sapiens];XP_009249479.1//PREDICTED: XIAP-associated factor 1 isoform X2 [Pongo abelii];XP_009249478.1//PREDICTED: XIAP-associated factor 1 isoform X1 [Pongo abelii]","4;1//3;3//A2MP1"]
[81027,3496,0.23,0.41,0.833990048561071,0.240079540408437,"*",0.1346784,"TUBB1","GO:0070062//extracellular exosome;GO:0005874//microtubule;GO:0005737//cytoplasm","GO:0005200//structural constituent of cytoskeleton;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0051225//spindle assembly","K07375//tubulin beta","XP_004062495.1//PREDICTED: tubulin beta-1 chain isoform X1 [Gorilla gorilla gorilla]","3//A2MP1"]
[9314,2912,5.88,10.47,0.832373382094444,{"v":5.42771723925593e-11,"d":"5.43E-11"},"*",{"v":5.29724e-12,"d":"5.30E-12"},"KLF4","GO:0005654//nucleoplasm;GO:0044798//nuclear transcription factor complex;GO:0005719//nuclear euchromatin;GO:0000790//nuclear chromatin;GO:0005737//cytoplasm","GO:0001010//transcription factor activity, sequence-specific DNA binding transcription factor recruiting;GO:0042826//histone deacetylase binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0003676//nucleic acid binding;GO:0001190//transcriptional activator activity, RNA polymerase II transcription factor binding;GO:1990841//promoter-specific chromatin binding;GO:0000987//proximal promoter sequence-specific DNA binding;GO:0008013//beta-catenin binding;GO:0001047//core promoter binding","GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0090051//negative regulation of cell migration involved in sprouting angiogenesis;GO:0071409//cellular response to cycloheximide;GO:0032270//positive regulation of cellular protein metabolic process;GO:0051973//positive regulation of telomerase activity;GO:0071499//cellular response to laminar fluid shear stress;GO:0048730//epidermis morphogenesis;GO:1904998//negative regulation of leukocyte adhesion to arterial endothelial cell;GO:0071363//cellular response to growth factor stimulus;GO:0046985//positive regulation of hemoglobin biosynthetic process;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0008285//negative regulation of cell proliferation;GO:0070301//cellular response to hydrogen peroxide;GO:0060761//negative regulation of response to cytokine stimulus;GO:0009913//epidermal cell differentiation;GO:0032526//response to retinoic acid;GO:2000342//negative regulation of chemokine (C-X-C motif) ligand 2 production;GO:1904798//positive regulation of core promoter binding;GO:1990830//cellular response to leukemia inhibitory factor;GO:0060070//canonical Wnt signaling pathway;GO:0034115//negative regulation of heterotypic cell-cell adhesion;GO:0019827//stem cell population maintenance;GO:0031077//post-embryonic camera-type eye development;GO:0045444//fat cell differentiation;GO:0048679//regulation of axon regeneration;GO:0035166//post-embryonic hemopoiesis;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0045415//negative regulation of interleukin-8 biosynthetic process","K17846//krueppel-like factor 4","NP_004226.3//Krueppel-like factor 4 isoform 2 [Homo sapiens];NP_001300981.1//Krueppel-like factor 4 isoform 1 [Homo sapiens]","1//3;5"]
[9636,685,3.32,5.91,0.831974888830608,0.0370638565302984,"*",0.01508634,"ISG15","GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005576//extracellular region","GO:0031386//protein tag","GO:0032649//regulation of interferon-gamma production;GO:0031397//negative regulation of protein ubiquitination;GO:0060337//type I interferon signaling pathway;GO:0051607//defense response to virus;GO:0019941//modification-dependent protein catabolic process;GO:0042742//defense response to bacterium;GO:0016032//viral process;GO:0019985//translesion synthesis;GO:0034340//response to type I interferon;GO:0030501//positive regulation of bone mineralization;GO:0032020//ISG15-protein conjugation;GO:0045071//negative regulation of viral genome replication;GO:0045648//positive regulation of erythrocyte differentiation;GO:0032480//negative regulation of type I interferon production","K12159//ubiquitin cross-reactive protein","NP_005092.1//ubiquitin-like protein ISG15 [Homo sapiens]","3//A2MP1"]
[7101,2631,0.09,0.16,0.830074998557688,0.628607217797138,"*",0.505908,"NR2E1","GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0003707//steroid hormone receptor activity;GO:0042826//histone deacetylase binding;GO:0008270//zinc ion binding;GO:0043565//sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0060041//retina development in camera-type eye;GO:0007399//nervous system development;GO:0048712//negative regulation of astrocyte differentiation;GO:0060164//regulation of timing of neuron differentiation;GO:0007601//visual perception;GO:0035019//somatic stem cell population maintenance;GO:0002118//aggressive behavior;GO:0021772//olfactory bulb development;GO:2000648//positive regulation of stem cell proliferation;GO:0060291//long-term synaptic potentiation;GO:0021764//amygdala development;GO:0021819//layer formation in cerebral cortex;GO:0045766//positive regulation of angiogenesis;GO:0048814//regulation of dendrite morphogenesis;GO:0090049//regulation of cell migration involved in sprouting angiogenesis;GO:0045165//cell fate commitment;GO:0035176//social behavior;GO:0021960//anterior commissure morphogenesis;GO:0021895//cerebral cortex neuron differentiation;GO:0006351//transcription, DNA-templated;GO:0021542//dentate gyrus development;GO:0043066//negative regulation of apoptotic process;GO:2000178//negative regulation of neural precursor cell proliferation;GO:0001662//behavioral fear response;GO:2000179//positive regulation of neural precursor cell proliferation;GO:0045665//negative regulation of neuron differentiation;GO:0021872//forebrain generation of neurons;GO:0030198//extracellular matrix organization;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0045787//positive regulation of cell cycle","K08545//nuclear receptor subfamily 2 group E member 1","NP_003260.1//nuclear receptor subfamily 2 group E member 1 isoform b [Homo sapiens];XP_012361509.1//PREDICTED: nuclear receptor subfamily 2 group E member 1 isoform X1 [Nomascus leucogenys]","4;1//3"]
[146456,940,0.35,0.62,0.824913293441909,0.539872505606167,"*",0.385826,"TMED6","GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","NA","GO:0006810//transport","K20351//p24 family protein gamma-5","NP_653277.2//transmembrane emp24 domain-containing protein 6 precursor [Homo sapiens]","3//A2MP1"]
[124044,2388,5.39,9.54,0.823703993253006,{"v":2.3864265621162E-8,"d":"2.39E-08"},"*",{"v":3.16268e-09,"d":"3.16E-09"},"SPATA2L","NA","NA","NA","K17595//spermatogenesis-associated protein 2","NP_689552.2//spermatogenesis-associated protein 2-like protein [Homo sapiens]","3//A2MP1"]
[81693,1574,0.26,0.46,0.823122237915921,0.447388326393427,"*",0.299986,"AMN","GO:0070062//extracellular exosome;GO:0010008//endosome membrane;GO:0005615//extracellular space;GO:0016324//apical plasma membrane;GO:0031526//brush border membrane;GO:0030139//endocytic vesicle;GO:0005905//clathrin-coated pit;GO:0043234//protein complex;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005102//receptor binding","GO:0015889//cobalamin transport;GO:0043001//Golgi to plasma membrane protein transport;GO:0006898//receptor-mediated endocytosis;GO:0007275//multicellular organism development;GO:0007588//excretion;GO:0034384//high-density lipoprotein particle clearance;GO:0009235//cobalamin metabolic process","K18259//protein amnionless","NP_112205.2//protein amnionless precursor [Homo sapiens]","3//A2MP1"]
[139212,1678,0.13,0.23,0.823122237915921,0.609092046275967,"*",0.451538,"PIH1D3","GO:0005737//cytoplasm","GO:0051087//chaperone binding","GO:0003341//cilium movement;GO:0030317//flagellated sperm motility;GO:0070286//axonemal dynein complex assembly","K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K02927//large subunit ribosomal protein L40e;K17985//activating molecule in BECN1-regulated autophagy protein 1;K01064//wingless-type MMTV integration site family, member 9;K20164//DENN domain-containing protein 5","NP_775765.1//protein PIH1D3 [Homo sapiens]","1//3"]
[8320,3118,0.39,0.69,0.823122237915921,0.168756994237288,"*",0.0872626,"EOMES","GO:0005634//nucleus","GO:0003677//DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0043565//sequence-specific DNA binding;GO:0001191//transcriptional repressor activity, RNA polymerase II transcription factor binding;GO:0003700//DNA binding transcription factor activity;GO:0001102//RNA polymerase II activating transcription factor binding","GO:0060809//mesodermal to mesenchymal transition involved in gastrulation;GO:0001714//endodermal cell fate specification;GO:0001829//trophectodermal cell differentiation;GO:0001706//endoderm formation;GO:0021772//olfactory bulb development;GO:0007420//brain development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0001707//mesoderm formation;GO:0045597//positive regulation of cell differentiation;GO:0021796//cerebral cortex regionalization;GO:0021895//cerebral cortex neuron differentiation;GO:0006351//transcription, DNA-templated;GO:0045664//regulation of neuron differentiation;GO:0002302//CD8-positive, alpha-beta T cell differentiation involved in immune response;GO:0032609//interferon-gamma production;GO:0002250//adaptive immune response;GO:0035914//skeletal muscle cell differentiation;GO:0019827//stem cell population maintenance;GO:0060706//cell differentiation involved in embryonic placenta development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0010002//cardioblast differentiation","K10173//eomesodermin protein","BAH13105.1//unnamed protein product [Homo sapiens];NP_001265111.1//eomesodermin homolog isoform 1 [Homo sapiens];NP_005433.2//eomesodermin homolog isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[8338,437,1.6,2.83,0.82273014794452,0.236918250592709,"*",0.1326232,"HIST2H2AC","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0000786//nucleosome","GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity","GO:0006342//chromatin silencing","K11251//histone H2A","NP_003508.1//histone H2A type 2-C [Homo sapiens]","2//1"]
[54507,4145,1.25,2.21,0.822118274729345,0.000471035662891278,"*",0.0001234058,"ADAMTSL4","GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0005614//interstitial matrix","GO:0002020//protease binding;GO:0008233//peptidase activity","GO:0043065//positive regulation of apoptotic process;GO:0002064//epithelial cell development;GO:0030198//extracellular matrix organization;GO:0036066//protein O-linked fucosylation;GO:0006915//apoptotic process","K08630//a disintegrin and metalloproteinase with thrombospondin motifs 16 [EC:3.4.24.-];K08625//a disintegrin and metalloproteinase with thrombospondin motifs 10 [EC:3.4.24.-];K09609//a disintegrin and metalloproteinase with thrombospondin motifs 20 [EC:3.4.24.-];K08632//a disintegrin and metalloproteinase with thrombospondin motifs 18 [EC:3.4.24.-]","XP_011507946.1//PREDICTED: ADAMTS-like protein 4 isoform X1 [Homo sapiens];XP_011507947.1//PREDICTED: ADAMTS-like protein 4 isoform X2 [Homo sapiens];NP_001275536.1//ADAMTS-like protein 4 isoform 3 precursor [Homo sapiens]","4;1//3;5"]
[7052,5127,62.99,111.35,0.821906841789814,{"v":1.88272226333333E-181,"d":"1.88E-181"},"*",{"v":4.24302e-184,"d":"4.24E-184"},"TGM2","GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0031226//intrinsic component of plasma membrane;GO:0005783//endoplasmic reticulum;GO:0005925//focal adhesion;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005886//plasma membrane","GO:0046872//metal ion binding;GO:0019904//protein domain specific binding;GO:0005525//GTP binding;GO:0003810//protein-glutamine gamma-glutamyltransferase activity","GO:0060445//branching involved in salivary gland morphogenesis;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway;GO:0045785//positive regulation of cell adhesion;GO:0051260//protein homooligomerization;GO:0050729//positive regulation of inflammatory response;GO:0032471//negative regulation of endoplasmic reticulum calcium ion concentration;GO:0043277//apoptotic cell clearance;GO:0051561//positive regulation of mitochondrial calcium ion concentration;GO:0018149//peptide cross-linking;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0001974//blood vessel remodeling;GO:0018153//isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine;GO:0043065//positive regulation of apoptotic process;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0060662//salivary gland cavitation","K05625//transglutaminase 2 [EC:2.3.2.13]","NP_945189.1//protein-glutamine gamma-glutamyltransferase 2 isoform b [Homo sapiens];NP_001310246.1//protein-glutamine gamma-glutamyltransferase 2 isoform c [Homo sapiens];NP_004604.2//protein-glutamine gamma-glutamyltransferase 2 isoform a [Homo sapiens];NP_001310247.1//protein-glutamine gamma-glutamyltransferase 2 isoform d [Homo sapiens]","1//3;3//A2MP1;2//1"]
[10068,1313,8.46,14.95,0.821415915965518,{"v":3.90783936713996e-05,"d":"3.91E-05"},"*",{"v":8.44244e-06,"d":"8.44E-06"},"IL18BP","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005576//extracellular region","GO:0048019//receptor antagonist activity;GO:0042007//interleukin-18 binding","GO:0042088//T-helper 1 type immune response;GO:0032496//response to lipopolysaccharide;GO:0071356//cellular response to tumor necrosis factor;GO:0070301//cellular response to hydrogen peroxide","K15698//RING finger protein 121","XP_009245053.1//PREDICTED: interleukin-18-binding protein isoform X1 [Pongo abelii];NP_001138527.1//interleukin-18-binding protein isoform b precursor [Homo sapiens];XP_009245054.1//PREDICTED: interleukin-18-binding protein isoform X2 [Pongo abelii];NP_766632.2//interleukin-18-binding protein isoform d precursor [Homo sapiens]","1//3;3//A2MP1;2//1"]
[2073,4091,1.57,2.77,0.819121417157562,1.18408988948498E-4,"*",{"v":2.76342E-5,"d":"2.76E-05"},"ERCC5","GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0004520//endodeoxyribonuclease activity;GO:0003697//single-stranded DNA binding;GO:0046872//metal ion binding;GO:0000405//bubble DNA binding;GO:0047485//protein N-terminus binding;GO:0042803//protein homodimerization activity;GO:0003690//double-stranded DNA binding","GO:0009650//UV protection;GO:0009411//response to UV;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0006296//nucleotide-excision repair, DNA incision, 5'-to lesion;GO:0006295//nucleotide-excision repair, DNA incision, 3'-to lesion;GO:0043066//negative regulation of apoptotic process;GO:0006294//nucleotide-excision repair, preincision complex assembly;GO:0010225//response to UV-C;GO:0033683//nucleotide-excision repair, DNA incision;GO:0006293//nucleotide-excision repair, preincision complex stabilization","K10846//DNA excision repair protein ERCC-5","NP_000114.2//DNA repair protein complementing XP-G cells [Homo sapiens]","3//A2MP1"]
[221749,2211,7.68,13.55,0.819114635520078,{"v":1.4333982945679e-10,"d":"1.43E-10"},"*",{"v":1.453678E-11,"d":"1.45E-11"},"PXDC1","NA","GO:0035091//phosphatidylinositol binding","NA","K13172//serine/arginine repetitive matrix protein 2;K13171//serine/arginine repetitive matrix protein 1","NP_899229.2//PX domain-containing protein 1 [Homo sapiens]","3//A2MP1"]
[79446,1380,5.74,10.12,0.818086648018622,{"v":3.84864851306795E-7,"d":"3.85E-07"},"*",{"v":5.99198e-08,"d":"5.99E-08"},"WDR25","NA","NA","NA","K12816//pre-mRNA-processing factor 17","NP_001337879.1//WD repeat-containing protein 25 isoform c [Homo sapiens];NP_001337878.1//WD repeat-containing protein 25 isoform b [Homo sapiens];NP_001154948.1//WD repeat-containing protein 25 isoform a [Homo sapiens]","1//3;2//1;5"]
[4815,986,0.59,1.04,0.817796668779251,0.402927189189189,"*",0.26132,"NINJ2","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane","NA","GO:0007399//nervous system development;GO:0007155//cell adhesion;GO:0042246//tissue regeneration;GO:0007158//neuron cell-cell adhesion","NA","NP_057617.2//ninjurin-2 isoform 1 [Homo sapiens];NP_001281274.1//ninjurin-2 isoform 2 [Homo sapiens];AAH57766.2//NINJ2 protein, partial [Homo sapiens]","1//3;5"]
[56892,1841,17.13,30.19,0.817545605429626,{"v":8.8786846921241e-19,"d":"8.88E-19"},"*",{"v":4.65778e-20,"d":"4.66E-20"},"TCIM","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016607//nuclear speck;GO:0005622//intracellular;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0005112//Notch binding","GO:0010739//positive regulation of protein kinase A signaling;GO:0002264//endothelial cell activation involved in immune response;GO:0043066//negative regulation of apoptotic process;GO:0034605//cellular response to heat;GO:1902806//regulation of cell cycle G1/S phase transition;GO:0042346//positive regulation of NF-kappaB import into nucleus;GO:0006915//apoptotic process;GO:0043620//regulation of DNA-templated transcription in response to stress;GO:1900020//positive regulation of protein kinase C activity;GO:0045746//negative regulation of Notch signaling pathway;GO:1903706//regulation of hemopoiesis","NA","XP_003432158.2//protein C8orf4 homolog [Canis lupus familiaris]",4]
[90288,2169,0.63,1.11,0.81713594285019,0.121272769147005,"*",0.0585638,"EFCAB12","NA","GO:0005509//calcium ion binding","NA","NA","NP_997190.1//EF-hand calcium-binding domain-containing protein 12 [Homo sapiens]","2//1"]
[57091,1892,0.25,0.44,0.815575428862573,0.344501586442079,"*",0.208698,"CASS4","GO:0005856//cytoskeleton;GO:0005925//focal adhesion;GO:0005737//cytoplasm","NA","GO:0007155//cell adhesion","K16832//enhancer of filamentation 1","NP_001157586.1//cas scaffolding protein family member 4 isoform b [Homo sapiens];NP_065089.2//cas scaffolding protein family member 4 isoform a [Homo sapiens];NP_001157587.1//cas scaffolding protein family member 4 isoform c [Homo sapiens]","1//3;3//A2MP1"]
[7128,4721,2.41,4.24,0.815031118333237,{"v":1.6691076097973e-07,"d":"1.67E-07"},"*",{"v":2.4743e-08,"d":"2.47E-08"},"TNFAIP3","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0005764//lysosome;GO:0005737//cytoplasm","GO:0070530//K63-linked polyubiquitin modification-dependent protein binding;GO:0003677//DNA binding;GO:0042802//identical protein binding;GO:0019900//kinase binding","GO:0001922//B-1 B cell homeostasis;GO:0071222//cellular response to lipopolysaccharide;GO:0070301//cellular response to hydrogen peroxide;GO:0006915//apoptotic process","K11859//tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12]","XP_012361594.1//PREDICTED: tumor necrosis factor alpha-induced protein 3 isoform X1 [Nomascus leucogenys];XP_004087703.1//PREDICTED: tumor necrosis factor alpha-induced protein 3 isoform X2 [Nomascus leucogenys];XP_003255830.1//PREDICTED: tumor necrosis factor alpha-induced protein 3 isoform X3 [Nomascus leucogenys]","1//3;3//A2MP1"]
[144406,3578,1.74,3.06,0.814444346843923,2.85650971870324E-4,"*",{"v":7.17078e-05,"d":"7.17E-05"},"WDR66","GO:0031514//motile cilium;GO:0005737//cytoplasm;GO:0005930//axoneme","NA","GO:0003341//cilium movement","K19538//retinitis pigmentosa 1;K19607//X-linked retinitis pigmentosa GTPase regulator","NP_001171474.1//cilia- and flagella-associated protein 251 isoform 2 [Homo sapiens];NP_653269.3//cilia- and flagella-associated protein 251 isoform 1 [Homo sapiens]","1//3;5"]
[3620,1944,4.91,8.63,0.813637534864262,{"v":2.82129822362869e-06,"d":"2.82E-06"},"*",{"v":5.02302e-07,"d":"5.02E-07"},"IDO1","GO:0032421//stereocilium bundle;GO:0005829//cytosol;GO:0030485//smooth muscle contractile fiber","GO:0009055//electron transfer activity;GO:0046872//metal ion binding;GO:0020037//heme binding;GO:0033754//indoleamine 2,3-dioxygenase activity;GO:0004833//tryptophan 2,3-dioxygenase activity","GO:0034276//kynurenic acid biosynthetic process;GO:0032693//negative regulation of interleukin-10 production;GO:0032496//response to lipopolysaccharide;GO:0042130//negative regulation of T cell proliferation;GO:0032735//positive regulation of interleukin-12 production;GO:0002376//immune system process;GO:0033555//multicellular organismal response to stress;GO:0036269//swimming behavior;GO:0070233//negative regulation of T cell apoptotic process;GO:0007565//female pregnancy;GO:0070234//positive regulation of T cell apoptotic process;GO:0002678//positive regulation of chronic inflammatory response;GO:0006569//tryptophan catabolic process;GO:0002534//cytokine production involved in inflammatory response;GO:0002830//positive regulation of type 2 immune response;GO:0002666//positive regulation of T cell tolerance induction;GO:0019441//tryptophan catabolic process to kynurenine","K00463//indoleamine 2,3-dioxygenase [EC:1.13.11.52]","NP_002155.1//indoleamine 2,3-dioxygenase 1 [Homo sapiens]",5]
[129530,1015,0.97,1.7,0.809478093950574,0.220303619614148,"*",0.1200954,"LYG1","GO:0005576//extracellular region","GO:0003796//lysozyme activity","GO:0016998//cell wall macromolecule catabolic process;GO:0009253//peptidoglycan catabolic process","K01446//peptidoglycan recognition protein","NP_777558.1//lysozyme g-like protein 1 precursor [Homo sapiens]","2//1"]
[284207,1633,3.81,6.67,0.807895763691263,0.000243751347480375,"*",{"v":6.02588E-5,"d":"6.03E-05"},"METRNL","GO:0070062//extracellular exosome;GO:0005615//extracellular space","GO:0005179//hormone activity","GO:0014850//response to muscle activity;GO:2000507//positive regulation of energy homeostasis;GO:0009409//response to cold;GO:0045444//fat cell differentiation;GO:0050873//brown fat cell differentiation;GO:0090336//positive regulation of brown fat cell differentiation;GO:0050728//negative regulation of inflammatory response","K00901//diacylglycerol kinase (ATP) [EC:2.7.1.107]","NP_001004431.1//meteorin-like protein precursor [Homo sapiens]","2//1"]
[7087,3005,0.32,0.56,0.807354922057604,0.220328921511428,"*",0.1200954,"ICAM5","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005178//integrin binding","GO:0007155//cell adhesion;GO:0030198//extracellular matrix organization;GO:0050776//regulation of immune response;GO:0006909//phagocytosis","K06769//intercellular adhesion molecule 5","NP_003250.3//intercellular adhesion molecule 5 precursor [Homo sapiens]","3//A2MP1"]
[1830,5561,0.32,0.56,0.807354922057604,0.0670097807095028,"*",0.0294442,"DSG3","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0001533//cornified envelope;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0030057//desmosome","GO:0005509//calcium ion binding","GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0031424//keratinization;GO:0070268//cornification","K07598//desmoglein 3","NP_001935.2//desmoglein-3 preproprotein [Homo sapiens]","2//1"]
[339766,5324,0.16,0.28,0.807354922057604,0.259472636130306,"*",0.1480914,"MROH2A","NA","NA","NA","K19719//collagen, type II, alpha;K06236//collagen, type I, alpha","XP_011509381.1//PREDICTED: maestro heat-like repeat-containing protein family member 2A isoform X5 [Homo sapiens]","1//3"]
[100507050,2820,0.08,0.14,0.807354922057604,0.629194518218623,"*",0.505908,"TPBGL","GO:0016021//integral component of membrane","NA","NA","K16628//collagen, type VII, alpha;K06236//collagen, type I, alpha","NP_001182457.1//trophoblast glycoprotein-like precursor [Homo sapiens]","1//3"]
[26249,6806,0.08,0.14,0.807354922057604,0.402810545208916,"*",0.26132,"KLHL3","GO:0005856//cytoskeleton;GO:0005829//cytosol;GO:0031463//Cul3-RING ubiquitin ligase complex","GO:0003779//actin binding;GO:0005198//structural molecule activity","GO:0070294//renal sodium ion absorption;GO:0070936//protein K48-linked ubiquitination;GO:0043687//post-translational protein modification;GO:0016567//protein ubiquitination;GO:0050801//ion homeostasis;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0072156//distal tubule morphogenesis","K10443//kelch-like protein 2/3","DAA27455.1//TPA: KIAA1129 protein-like [Bos taurus];XP_021520606.1//kelch-like protein 3 isoform X3 [Aotus nancymaae];XP_011714779.1//PREDICTED: kelch-like protein 3 isoform X3 [Macaca nemestrina]","1//3;2//1"]
[2155,2892,0.08,0.14,0.807354922057604,0.628656117619603,"*",0.505908,"F7","NA","NA","NA","K01320//coagulation factor VII [EC:3.4.21.21]","XP_009425587.1//PREDICTED: LOW QUALITY PROTEIN: coagulation factor VII [Pan troglodytes];XP_009247078.1//PREDICTED: coagulation factor VII isoform X2 [Pongo abelii]","1//3;4;3//A2MP1"]
[283383,5405,0.04,0.07,0.807354922057604,0.628411694556765,"*",0.505908,"ADGRD1","GO:0005622//intracellular;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004930//G-protein coupled receptor activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0007166//cell surface receptor signaling pathway","K08465//G protein-coupled receptor 133","XP_016780139.1//PREDICTED: adhesion G-protein coupled receptor D1 isoform X1 [Pan troglodytes];NP_942122.2//adhesion G-protein coupled receptor D1 isoform 1 precursor [Homo sapiens]","1//3;4"]
[5630,1833,0.4,0.7,0.807354922057604,0.287590168627451,"*",0.1671098,"PRPH","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005882//intermediate filament;GO:0045098//type III intermediate filament","GO:0005198//structural molecule activity","NA","K07607//peripherin","XP_012296710.1//peripherin isoform X2 [Aotus nancymaae]","3//A2MP1"]
[4005,1605,0.2,0.35,0.807354922057604,0.540109063535185,"*",0.385826,"LMO2","GO:0005654//nucleoplasm;GO:0005667//transcription factor complex","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0070888//E-box binding;GO:0001190//transcriptional activator activity, RNA polymerase II transcription factor binding;GO:0046872//metal ion binding;GO:0043425//bHLH transcription factor binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0048037//cofactor binding;GO:0001102//RNA polymerase II activating transcription factor binding","GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007275//multicellular organism development;GO:1902036//regulation of hematopoietic stem cell differentiation;GO:0042789//mRNA transcription from RNA polymerase II promoter;GO:0097067//cellular response to thyroid hormone stimulus","K15612//rhombotin-2","XP_006864973.1//PREDICTED: Wilms tumor protein 1-interacting protein-like [Chrysochloris asiatica];XP_011722342.1//PREDICTED: rhombotin-2 isoform X1 [Macaca nemestrina];XP_008000602.1//PREDICTED: rhombotin-2 isoform X1 [Chlorocebus sabaeus]","1//3;3//A2MP1"]
[3075,2608,4.92,8.58,0.802319332160306,{"v":1.45126065807327e-11,"d":"1.45E-11"},"*",{"v":1.33915E-12,"d":"1.34E-12"},"CFH","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0072562//blood microparticle;GO:0005576//extracellular region","GO:0043395//heparan sulfate proteoglycan binding;GO:0008201//heparin binding","GO:0030449//regulation of complement activation;GO:0006956//complement activation;GO:0006957//complement activation, alternative pathway;GO:0016032//viral process","K04004//complement factor H","NP_000177.2//complement factor H isoform a precursor [Homo sapiens];NP_001014975.1//complement factor H isoform b precursor [Homo sapiens]","3//A2MP1;2//1"]
[716,2775,16.76,29.22,0.801934029104147,{"v":2.80948045393258e-23,"d":"2.81E-23"},"*",{"v":1.095722e-24,"d":"1.10E-24"},"C1S","GO:0070062//extracellular exosome;GO:0072562//blood microparticle;GO:0005576//extracellular region","GO:0004252//serine-type endopeptidase activity;GO:0042802//identical protein binding;GO:0005509//calcium ion binding","GO:0006958//complement activation, classical pathway;GO:0030449//regulation of complement activation;GO:0006956//complement activation;GO:0001867//complement activation, lectin pathway","K01331//complement component 1, s subcomponent [EC:3.4.21.42]","NP_001725.1//complement C1s subcomponent isoform 1 preproprotein [Homo sapiens]","1//3;4;3//A2MP1"]
[53842,2708,0.35,0.61,0.80145432061792,0.279111298709188,"*",0.1610822,"CLDN22","GO:0016021//integral component of membrane;GO:0005923//bicellular tight junction;GO:0005886//plasma membrane","GO:0042802//identical protein binding;GO:0005198//structural molecule activity","GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules","K06087//claudin","NP_001104789.1//claudin-22 [Homo sapiens]","1//3"]
[135112,4410,17.48,30.45,0.800737043293096,{"v":1.2211217257732E-32,"d":"1.22E-32"},"*",{"v":2.96604E-34,"d":"2.97E-34"},"NCOA7","GO:0005634//nucleus;GO:0005622//intracellular","GO:0035257//nuclear hormone receptor binding;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity","GO:1902083//negative regulation of peptidyl-cysteine S-nitrosylation;GO:1903204//negative regulation of oxidative stress-induced neuron death;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated","K12581//CCR4-NOT transcription complex subunit 7/8;K21841//TBC1 domain family member 24;K20634//Rho GTPase-activating protein 9;K12587//exosome complex component MTR3","NP_861447.3//nuclear receptor coactivator 7 isoform 1 [Homo sapiens];NP_001186551.1//nuclear receptor coactivator 7 isoform 4 [Homo sapiens];NP_001116314.1//nuclear receptor coactivator 7 isoform 2 [Homo sapiens]","1//3;4;2//1"]
[493861,1486,4.63,8.06,0.799767645267731,0.000136133977777778,"*",{"v":3.2214E-5,"d":"3.22E-05"},"EID3","NA","NA","NA","K22182//thioredoxin reductase (NADPH) [EC:1.8.1.9]","XP_008002676.1//PREDICTED: thioredoxin reductase 1, cytoplasmic isoform X8 [Chlorocebus sabaeus]","2//1"]
[192134,2560,0.23,0.4,0.798366138830349,0.402732820067535,"*",0.26132,"B3GNT6","GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0008499//UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity;GO:0047223//beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity;GO:0008378//galactosyltransferase activity;GO:0047224//acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity","GO:0006486//protein glycosylation;GO:0016269//O-glycan processing, core 3;GO:0009101//glycoprotein biosynthetic process;GO:0016266//O-glycan processing","K00739//acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase [EC:2.4.1.147]","NP_619651.3//acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase [Homo sapiens]",4]
[692312,3263,8.03,13.96,0.797827048692338,{"v":3.78191658483755e-15,"d":"3.78E-15"},"*",{"v":2.62324e-16,"d":"2.62E-16"},"PPAN-P2RY11","GO:0005634//nucleus;GO:0005730//nucleolus;GO:0016021//integral component of membrane;GO:0030687//preribosome, large subunit precursor","GO:0045028//G-protein coupled purinergic nucleotide receptor activity;GO:0003723//RNA binding;GO:0019843//rRNA binding","GO:0000027//ribosomal large subunit assembly","K14859//ribosome biogenesis protein SSF1/2","NP_001035754.1//PPAN-P2RY11 protein isoform 1 [Homo sapiens];NP_001185619.1//PPAN-P2RY11 protein isoform 2 [Homo sapiens]","1//3;2//1"]
[10326,1971,0.34,0.59,0.795180208111502,0.236838792263835,"*",0.1326232,"SIRPB1","GO:0070062//extracellular exosome;GO:0030667//secretory granule membrane;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","NA","GO:0007165//signal transduction;GO:0043312//neutrophil degranulation;GO:0007166//cell surface receptor signaling pathway;GO:0045087//innate immune response","K06551//signal-regulatory protein alpha/beta1/gamma","NP_006056.2//signal-regulatory protein beta-1 isoform 1 precursor [Homo sapiens];NP_001317568.1//signal-regulatory protein beta-1 isoform 4 precursor [Homo sapiens];NP_001077379.1//signal-regulatory protein beta-1 isoform 2 precursor [Homo sapiens];NP_001129316.1//signal-regulatory protein beta-1 isoform 3 precursor [Homo sapiens]","4;1//3;3//A2MP1"]
[255783,849,16.25,28.19,0.794743759767243,{"v":5.54174592466368E-8,"d":"5.54E-08"},"*",{"v":7.73638e-09,"d":"7.74E-09"},"INAFM1","GO:0016021//integral component of membrane","NA","NA","NA","EAW57469.1//hCG1820496 [Homo sapiens]",5]
[57732,3293,0.88,1.52,0.788495894806288,0.0244843371846079,"*",0.00944028,"ZFYVE28","GO:0031901//early endosome membrane;GO:0005829//cytosol","GO:0046872//metal ion binding;GO:0032266//phosphatidylinositol-3-phosphate binding","GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0007175//negative regulation of epidermal growth factor-activated receptor activity","K06236//collagen, type I, alpha;K18082//myotubularin-related protein 3/4 [EC:3.1.3.48 3.1.3.64 3.1.3.95];K17603//zinc finger FYVE domain-containing protein 1;K06831//galectin-3","NP_001166129.1//lateral signaling target protein 2 homolog isoform 5 [Homo sapiens];NP_001166127.1//lateral signaling target protein 2 homolog isoform 3 [Homo sapiens];NP_001166128.1//lateral signaling target protein 2 homolog isoform 4 [Homo sapiens];NP_066023.2//lateral signaling target protein 2 homolog isoform 2 [Homo sapiens];XP_017731740.1//PREDICTED: lateral signaling target protein 2 homolog isoform X7 [Rhinopithecus bieti]","1//3;2//1"]
[84527,2949,0.77,1.33,0.788495894806288,0.0896911001087548,"*",0.0413026,"ZNF559","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","XP_017171189.1//PREDICTED: zinc finger protein 431-like, partial [Mus musculus];XP_017169913.1//PREDICTED: predicted gene 14295 isoform X1 [Mus musculus]","1//3;2//1"]
[23217,4757,0.33,0.57,0.788495894806288,0.251487957624682,"*",0.1423692,"ZFR2","NA","GO:0008270//zinc ion binding;GO:0003676//nucleic acid binding","NA","K08888//megakaryocyte-associated tyrosine kinase [EC:2.7.10.2];K17602//YLP motif-containing protein 1;K13203//zinc finger RNA-binding protein;K12968//double-stranded RNA-specific adenosine deaminase [EC:3.5.4.37]","NP_001139112.1//zinc finger RNA-binding protein 2 isoform 2 [Homo sapiens];NP_055989.1//zinc finger RNA-binding protein 2 isoform 1 [Homo sapiens]","1//3"]
[92960,1061,1.39,2.4,0.787949522885011,0.130073534878981,"*",0.0639212,"PEX11G","GO:0005779//integral component of peroxisomal membrane;GO:0031231//intrinsic component of peroxisomal membrane;GO:0043234//protein complex;GO:0005777//peroxisome","NA","GO:0044375//regulation of peroxisome size;GO:0016559//peroxisome fission","K13353//peroxin-11C","NP_542393.1//peroxisomal membrane protein 11C isoform 1 [Homo sapiens];NP_001257468.1//peroxisomal membrane protein 11C isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[1465,1932,207.54,357.76,0.785602673749106,{"v":3.03948119096774e-212,"d":"3.04E-212"},"*",{"v":5.89858e-215,"d":"5.90E-215"},"CSRP1","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005925//focal adhesion","GO:0046872//metal ion binding;GO:0003723//RNA binding;GO:0008270//zinc ion binding","GO:0070527//platelet aggregation","K09377//cysteine and glycine-rich protein","XP_003767613.2//PREDICTED: cysteine and glycine-rich protein 1 [Sarcophilus harrisii];XP_011845940.1//PREDICTED: cysteine and glycine-rich protein 1 isoform X1 [Mandrillus leucophaeus];EDL39573.1//cysteine and glycine-rich protein 1, isoform CRA_a, partial [Mus musculus]","1//3;2//1"]
[641371,1603,2.46,4.24,0.785405949223959,0.00504564959643687,"*",1.631134E-3,"ACOT1","NA","NA","NA","K01068//acyl-coenzyme A thioesterase 1/2/4 [EC:3.1.2.2]","XP_012596914.2//acyl-coenzyme A thioesterase 1 isoform X2 [Microcebus murinus]","1//3"]
[15,1105,0.47,0.81,0.785261151206987,0.315494397938144,"*",0.1877482,"AANAT","GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm","GO:0004059//aralkylamine N-acetyltransferase activity;GO:0071889//14-3-3 protein binding;GO:0004060//arylamine N-acetyltransferase activity","GO:0007623//circadian rhythm;GO:0032868//response to insulin;GO:0046219//indolalkylamine biosynthetic process;GO:0034695//response to prostaglandin E;GO:0009416//response to light stimulus;GO:0034097//response to cytokine;GO:0010043//response to zinc ion;GO:0046688//response to copper ion;GO:0071320//cellular response to cAMP;GO:0030187//melatonin biosynthetic process;GO:0051592//response to calcium ion;GO:0006474//N-terminal protein amino acid acetylation;GO:0009648//photoperiodism;GO:0051412//response to corticosterone","K00669//arylalkylamine N-acetyltransferase [EC:2.3.1.87]","XP_016879748.1//PREDICTED: serotonin N-acetyltransferase isoform X1 [Homo sapiens];NP_001160051.1//serotonin N-acetyltransferase isoform 1 [Homo sapiens]","1//3;2//1"]
[151651,2857,0.36,0.62,0.784271308944563,0.330740895694777,"*",0.1986226,"EFHB","NA","GO:0005509//calcium ion binding","NA","K02183//calmodulin;K10869//RAD51-like protein 1;K04460//serine/threonine-protein phosphatase 5 [EC:3.1.3.16]","NP_001317617.1//EF-hand domain-containing family member B isoform 2 [Homo sapiens];NP_653316.3//EF-hand domain-containing family member B isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[51365,1801,0.18,0.31,0.784271308944563,0.539919800613228,"*",0.385826,"PLA1A","GO:0070062//extracellular exosome;GO:0005576//extracellular region;GO:0002080//acrosomal membrane","GO:0052739//phosphatidylserine 1-acylhydrolase activity;GO:0052689//carboxylic ester hydrolase activity;GO:0008970//phosphatidylcholine 1-acylhydrolase activity","GO:0006658//phosphatidylserine metabolic process;GO:0016042//lipid catabolic process;GO:0036150//phosphatidylserine acyl-chain remodeling;GO:0006629//lipid metabolic process","K13618//phospholipase A1 member A [EC:3.1.1.-]","NP_001193889.1//phospholipase A1 member A isoform 2 precursor [Homo sapiens];NP_001280154.1//phospholipase A1 member A isoform 4 [Homo sapiens];NP_056984.1//phospholipase A1 member A isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[23329,7659,0.25,0.43,0.782408564927373,0.0611081955376422,"*",0.0265756,"TBC1D30","GO:0012505//endomembrane system;GO:0005929//cilium;GO:0036064//ciliary basal body;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0017137//Rab GTPase binding;GO:0005096//GTPase activator activity","GO:0006886//intracellular protein transport;GO:0090630//activation of GTPase activity;GO:0031338//regulation of vesicle fusion;GO:0043547//positive regulation of GTPase activity;GO:1902018//negative regulation of cilium assembly","K20165//TBC1 domain family member 2A;K19953//TBC1 domain family member 6","NP_001317115.1//TBC1 domain family member 30 isoform 2 [Homo sapiens];NP_056094.1//TBC1 domain family member 30 isoform 1 [Homo sapiens];BAA76828.1//KIAA0984 protein, partial [Homo sapiens]","1//3"]
[285966,4867,1.07,1.84,0.782094969655866,0.00984390144023218,"*",0.00339736,"TCAF2","GO:0005886//plasma membrane","GO:0044325//ion channel binding","GO:0006810//transport;GO:0030335//positive regulation of cell migration;GO:0030336//negative regulation of cell migration;GO:0090314//positive regulation of protein targeting to membrane;GO:1901529//positive regulation of anion channel activity;GO:0010360//negative regulation of anion channel activity","K22069//LYR motif-containing protein 4;K12581//CCR4-NOT transcription complex subunit 7/8;K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K01587//phosphoribosylaminoimidazole carboxylase / phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:4.1.1.21 6.3.2.6];K15259//poly [ADP-ribose] polymerase 7/11/12/13 [EC:2.4.2.30]","EHH61538.1//hypothetical protein EGM_19442 [Macaca fascicularis];NP_001123498.2//TRPM8 channel-associated factor 2 isoform B [Homo sapiens]","1//3;2//1"]
[93349,2519,2.22,3.81,0.779231321143216,9.39609007874016E-4,"*",0.00026146,"SP140L","GO:0016604//nuclear body","GO:0046872//metal ion binding;GO:0003677//DNA binding","NA","K15413//nuclear autoantigen Sp-100","NP_612411.4//nuclear body protein SP140-like protein isoform 1 [Homo sapiens];NP_001339823.1//nuclear body protein SP140-like protein isoform 6 [Homo sapiens];NP_001339821.1//nuclear body protein SP140-like protein isoform 4 [Homo sapiens];NP_001295092.1//nuclear body protein SP140-like protein isoform 3 [Homo sapiens];NP_001339822.1//nuclear body protein SP140-like protein isoform 5 [Homo sapiens];NP_001295091.1//nuclear body protein SP140-like protein isoform 2 [Homo sapiens]","1//3;2//1;5"]
[654254,2341,0.07,0.12,0.777607578663552,0.782423613400957,"*",0.685686,"ZNF732","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_003310254.2//PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 732 [Pan troglodytes]","2//1"]
[1844,1708,0.14,0.24,0.777607578663552,0.629243509460407,"*",0.505908,"DUSP2","GO:0005634//nucleus;GO:0031965//nuclear membrane","GO:0008330//protein tyrosine/threonine phosphatase activity;GO:0017017//MAP kinase tyrosine/serine/threonine phosphatase activity;GO:0051019//mitogen-activated protein kinase binding;GO:0004725//protein tyrosine phosphatase activity","GO:0006470//protein dephosphorylation;GO:0001706//endoderm formation;GO:0000188//inactivation of MAPK activity","K04459//dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48]","XP_016804459.1//PREDICTED: dual specificity protein phosphatase 2 [Pan troglodytes]","3//A2MP1"]
[27334,3397,0.07,0.12,0.777607578663552,0.628900730894942,"*",0.505908,"P2RY10","NA","NA","NA","K04274//purinergic receptor P2Y, G protein-coupled, 10","NP_001311154.1//putative P2Y purinoceptor 10 isoform c [Homo sapiens];XP_004064490.1//PREDICTED: putative P2Y purinoceptor 10 isoform X1 [Gorilla gorilla gorilla];XP_002831884.1//PREDICTED: putative P2Y purinoceptor 10 isoform X2 [Pongo abelii]","1//3;3//A2MP1;2//1"]
[389602,4584,0.07,0.12,0.777607578663552,0.53982521888412,"*",0.385826,"LOC389602","NA","NA","NA","NA","EAL23914.1//hypothetical gene supported by AK124321 [Homo sapiens]","2//1"]
[919,1687,0.14,0.24,0.777607578663552,0.628802862745098,"*",0.505908,"CD247","GO:0042101//T cell receptor complex;GO:0042105//alpha-beta T cell receptor complex;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0042802//identical protein binding;GO:0004888//transmembrane signaling receptor activity;GO:1990782//protein tyrosine kinase binding;GO:0042803//protein homodimerization activity","GO:0051289//protein homotetramerization;GO:0050852//T cell receptor signaling pathway;GO:0050690//regulation of defense response to virus by virus;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0007166//cell surface receptor signaling pathway;GO:0031295//T cell costimulation;GO:0050776//regulation of immune response;GO:0070207//protein homotrimerization;GO:0002250//adaptive immune response","K06453//CD3Z antigen, zeta polypeptide","EAW90790.1//CD247 antigen, isoform CRA_a [Homo sapiens]","3//A2MP1;2//1"]
[64857,7642,24.84,42.56,0.776832977280708,{"v":6.52744721263158e-100,"d":"6.53E-100"},"*",{"v":3.88198e-102,"d":"3.88E-102"},"PLEKHG2","GO:0005829//cytosol","GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005089//Rho guanyl-nucleotide exchange factor activity","GO:0030833//regulation of actin filament polymerization;GO:0043065//positive regulation of apoptotic process;GO:0035023//regulation of Rho protein signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction","K20685//guanine nucleotide exchange factor MCF2;K16463//centrosomal protein CEP170;K05769//Rho guanine nucleotide exchange factor 4/29","NP_001338623.1//pleckstrin homology domain-containing family G member 2 isoform 3 [Homo sapiens];NP_001338622.1//pleckstrin homology domain-containing family G member 2 isoform 2 [Homo sapiens];NP_073746.2//pleckstrin homology domain-containing family G member 2 isoform 1 [Homo sapiens]","1//3;2//1"]
[4071,1712,276.87,474.29,0.776560710495204,{"v":1.70266105333333E-243,"d":"1.70E-243"},"*",{"v":2.23838E-246,"d":"2.24E-246"},"TM4SF1","GO:0005887//integral component of plasma membrane","NA","NA","K00681//gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13];K13624//ceruloplasmin [EC:1.16.3.1]","NP_055035.1//transmembrane 4 L6 family member 1 [Homo sapiens]","2//1"]
[7126,3822,27.05,46.32,0.776006659275059,{"v":3.80474056666667e-54,"d":"3.80E-54"},"*",{"v":4.85894e-56,"d":"4.86E-56"},"TNFAIP1","GO:0005768//endosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0031463//Cul3-RING ubiquitin ligase complex","GO:0019904//protein domain specific binding;GO:0017049//GTP-Rho binding;GO:0004842//ubiquitin-protein transferase activity","GO:0016477//cell migration;GO:0006260//DNA replication;GO:0016567//protein ubiquitination;GO:0051260//protein homooligomerization;GO:0045740//positive regulation of DNA replication;GO:0006915//apoptotic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0009790//embryo development;GO:0006955//immune response;GO:0035024//negative regulation of Rho protein signal transduction;GO:0043149//stress fiber assembly","K15074//BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein","OBS67400.1//hypothetical protein A6R68_04102 [Neotoma lepida]",4]
[389362,753,15.28,26.16,0.775717997462334,{"v":2.86384175501843e-07,"d":"2.86E-07"},"*",{"v":4.37626e-08,"d":"4.38E-08"},"PSMG4","GO:0000502//proteasome complex","NA","GO:0043248//proteasome assembly","K11878//proteasome assembly chaperone 4","NP_001122063.1//proteasome assembly chaperone 4 isoform b [Homo sapiens];NP_001122064.1//proteasome assembly chaperone 4 isoform a [Homo sapiens];NP_001129222.1//proteasome assembly chaperone 4 isoform c [Homo sapiens]","1//3"]
[12,1629,0.55,0.94,0.773229138152977,0.259415727996491,"*",0.1480914,"SERPINA3","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0072562//blood microparticle","GO:0004867//serine-type endopeptidase inhibitor activity","NA","K04525//serpin peptidase inhibitor, clade A","EAW81588.1//serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3, isoform CRA_b [Homo sapiens]",4]
[3866,1861,0.48,0.82,0.772589503896927,0.259444178942751,"*",0.1480914,"KRT15","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005882//intermediate filament","GO:0097110//scaffold protein binding;GO:0005198//structural molecule activity;GO:0005200//structural constituent of cytoskeleton","GO:0008544//epidermis development;GO:0031424//keratinization;GO:0070268//cornification","K07604//type I keratin, acidic","NP_002266.2//keratin, type I cytoskeletal 15 [Homo sapiens]","3//A2MP1"]
[114026,2627,0.48,0.82,0.772589503896927,0.131763628904665,"*",0.0650652,"ZIM3","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_012630316.1//zinc finger protein 568 isoform X1 [Microcebus murinus]","1//3"]
[124975,2254,1.81,3.09,0.771617140821169,0.0129979713054144,"*",0.00464376,"GGT6","GO:0070062//extracellular exosome;GO:0016021//integral component of membrane","GO:0102953//hypoglycin A gamma-glutamyl transpeptidase activity;GO:0036374//glutathione hydrolase activity","GO:0006751//glutathione catabolic process;GO:1901750//leukotriene D4 biosynthetic process;GO:0006750//glutathione biosynthetic process","K00681//gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]","NP_001275632.1//gamma-glutamyltransferase 6 isoform d [Homo sapiens];NP_001275633.1//gamma-glutamyltransferase 6 isoform e [Homo sapiens];NP_699169.2//gamma-glutamyltransferase 6 isoform b [Homo sapiens];NP_001116362.1//gamma-glutamyltransferase 6 isoform a [Homo sapiens];NP_001275631.1//gamma-glutamyltransferase 6 isoform c [Homo sapiens]","1//3;3//A2MP1;2//1"]
[353322,953,1.73,2.95,0.769942916612479,0.118745610307132,"*",0.0571204,"ANKRD37","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005739//mitochondrion","NA","NA","K15502//serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A","XP_016863665.1//PREDICTED: ankyrin repeat domain-containing protein 37 isoform X1 [Homo sapiens]","3//A2MP1"]
[118471,786,0.61,1.04,0.769702380578206,0.344608419681621,"*",0.208698,"PRAP1","GO:0005576//extracellular region","NA","NA","K21250//proline-rich acidic protein 1","NP_001138673.1//proline-rich acidic protein 1 isoform 2 precursor [Homo sapiens];NP_660203.3//proline-rich acidic protein 1 isoform 1 precursor [Homo sapiens]","1//3;4"]
[9590,8412,14.11,24.04,0.768718908113921,{"v":1.11221161385475E-59,"d":"1.11E-59"},"*",{"v":1.246312E-61,"d":"1.25E-61"},"AKAP12","GO:0005925//focal adhesion;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0051018//protein kinase A binding;GO:0008179//adenylate cyclase binding","GO:0006605//protein targeting;GO:0007165//signal transduction;GO:0090036//regulation of protein kinase C signaling;GO:0010739//positive regulation of protein kinase A signaling;GO:0030819//positive regulation of cAMP biosynthetic process","K16528//A-kinase anchor protein 12","XP_004044877.1//PREDICTED: A-kinase anchor protein 12 isoform X2 [Gorilla gorilla gorilla];XP_018885117.1//PREDICTED: A-kinase anchor protein 12 isoform X1 [Gorilla gorilla gorilla]","3//A2MP1;2//1"]
[389816,1212,1.82,3.1,0.768329765075542,0.0598990384281999,"*",0.025956,"LRRC26","GO:0070062//extracellular exosome;GO:0005856//cytoskeleton;GO:0005730//nucleolus;GO:0005887//integral component of plasma membrane;GO:0001650//fibrillar center;GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0008076//voltage-gated potassium channel complex","GO:0005249//voltage-gated potassium channel activity;GO:0044325//ion channel binding;GO:0015459//potassium channel regulator activity;GO:0099104//potassium channel activator activity","GO:0071805//potassium ion transmembrane transport;GO:1903818//positive regulation of voltage-gated potassium channel activity","K06838//slit 1","NP_001013675.1//leucine-rich repeat-containing protein 26 precursor [Homo sapiens]","2//1"]
[1847,2545,24.57,41.85,0.768329765075541,{"v":4.99700098507463e-32,"d":"5.00E-32"},"*",{"v":1.25754e-33,"d":"1.26E-33"},"DUSP5","NA","NA","NA","K04459//dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48]","EAW49559.1//dual specificity phosphatase 5, isoform CRA_a [Homo sapiens]","3//A2MP1"]
[152078,1124,0.3,0.51,0.765534746362977,0.539967103907482,"*",0.385826,"PQLC2L","GO:0016021//integral component of membrane","NA","NA","K05543//tRNA-dihydrouridine synthase 2 [EC:1.3.1.91]","NP_001230658.1//putative uncharacterized protein PQLC2L isoform 4 [Homo sapiens];NP_001123474.1//putative uncharacterized protein PQLC2L isoform 1 [Homo sapiens];NP_001093247.1//putative uncharacterized protein PQLC2L isoform 3 [Homo sapiens];NP_001123473.1//putative uncharacterized protein PQLC2L isoform 2 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[225689,1904,0.3,0.51,0.765534746362977,0.40277167888846,"*",0.26132,"MAPK15","GO:0005634//nucleus;GO:0005622//intracellular;GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0005524//ATP binding;GO:0017124//SH3 domain binding;GO:0004707//MAP kinase activity","GO:1904355//positive regulation of telomere capping;GO:0010468//regulation of gene expression;GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0051973//positive regulation of telomerase activity;GO:0046777//protein autophosphorylation","K19603//mitogen-activated protein kinase 15 [EC:2.7.11.24]","NP_620590.2//mitogen-activated protein kinase 15 [Homo sapiens]","2//1"]
[100507588,1256,1.3,2.21,0.765534746362977,0.118730158698764,"*",0.0571204,"TGFBR3L","GO:0016021//integral component of membrane","NA","NA","K05843//transforming growth factor, beta receptor III","NP_001182188.1//transforming growth factor-beta receptor type 3-like protein [Homo sapiens]","1//3"]
[27324,4711,0.1,0.17,0.765534746362977,0.482548038412292,"*",0.330298,"TOX3","GO:0005634//nucleus","GO:0003682//chromatin binding;GO:0042803//protein homodimerization activity;GO:0034056//estrogen response element binding;GO:0051219//phosphoprotein binding","GO:0043524//negative regulation of neuron apoptotic process;GO:0006351//transcription, DNA-templated;GO:0042981//regulation of apoptotic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006915//apoptotic process","K04650//nuclear receptor co-repressor 1","NP_001073899.2//TOX high mobility group box family member 3 isoform 1 [Homo sapiens];NP_001139660.1//TOX high mobility group box family member 3 isoform 2 [Homo sapiens]","3//A2MP1;2//1"]
[874,1128,5.29,8.98,0.763447722627121,0.000858914987525516,"*",0.00023707,"CBR3","GO:0005654//nucleoplasm;GO:0005615//extracellular space;GO:0005829//cytosol","GO:0070402//NADPH binding;GO:0004090//carbonyl reductase (NADPH) activity;GO:0000253//3-keto sterol reductase activity","GO:0042376//phylloquinone catabolic process;GO:0050890//cognition;GO:0006805//xenobiotic metabolic process","K00084//carbonyl reductase 3 [EC:1.1.1.184]","NP_001227.1//carbonyl reductase [NADPH] 3 [Homo sapiens]","3//A2MP1"]
[79078,1036,3.09,5.24,0.761959973633076,0.0215849434220532,"*",0.00817374,"C1orf50","NA","GO:0042802//identical protein binding","NA","NA","XP_003812918.1//PREDICTED: uncharacterized protein C1orf50 homolog [Pan paniscus]","3//A2MP1"]
[389161,2491,0.59,1,0.761213140412884,0.13005696711247,"*",0.0639212,"ANKUB1","NA","NA","NA","K04453//Max protein;K18492//insulin gene enhancer protein ISL-2","NP_001138432.1//protein ANKUB1 isoform 1 [Homo sapiens];XP_003826524.1//PREDICTED: protein ANKUB1 [Pan paniscus];NP_001302434.1//protein ANKUB1 isoform 2 [Homo sapiens]","1//3;2//1"]
[567,987,209.41,354.62,0.759943566985665,{"v":4.52304633402062e-99,"d":"4.52E-99"},"*",{"v":2.74656e-101,"d":"2.75E-101"},"B2M","GO:1990712//HFE-transferrin receptor complex;GO:0070062//extracellular exosome;GO:0042612//MHC class I protein complex;GO:0005925//focal adhesion;GO:0009897//external side of plasma membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol","GO:0042802//identical protein binding","GO:0033077//T cell differentiation in thymus;GO:0002237//response to molecule of bacterial origin;GO:0033216//ferric iron import;GO:1904440//positive regulation of ferrous iron import across plasma membrane;GO:0055072//iron ion homeostasis;GO:1904437//positive regulation of transferrin receptor binding;GO:0010977//negative regulation of neuron projection development;GO:0071283//cellular response to iron(III) ion;GO:1900121//negative regulation of receptor binding;GO:0045646//regulation of erythrocyte differentiation;GO:0001895//retina homeostasis;GO:0002481//antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent;GO:0019885//antigen processing and presentation of endogenous peptide antigen via MHC class I;GO:0071281//cellular response to iron ion;GO:1904434//positive regulation of ferrous iron binding;GO:0002726//positive regulation of T cell cytokine production;GO:0006955//immune response;GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0048260//positive regulation of receptor-mediated endocytosis;GO:0042026//protein refolding","K08055//beta-2-microglobulin","CAG33347.1//B2M [Homo sapiens]","2//1"]
[56956,2515,0.13,0.22,0.758991900496205,0.539777940444912,"*",0.385826,"LHX9","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003714//transcription corepressor activity;GO:0043565//sequence-specific DNA binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0035262//gonad morphogenesis;GO:0008585//female gonad development;GO:0008283//cell proliferation;GO:0006355//regulation of transcription, DNA-templated;GO:0008045//motor neuron axon guidance;GO:0008584//male gonad development","K09373//LIM homeobox protein 2/9","NP_001014434.1//LIM/homeobox protein Lhx9 isoform 2 [Homo sapiens];NP_064589.2//LIM/homeobox protein Lhx9 isoform 1 [Homo sapiens]","1//3;2//1"]
[7584,2664,1.44,2.43,0.754887502163469,0.0101355882293362,"*",0.00350818,"ZNF35","GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm","GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","NA","K09228//KRAB domain-containing zinc finger protein","XP_015996789.1//PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 35 [Rousettus aegyptiacus]","3//A2MP1"]
[4502,499,513.44,866.39,0.754820896512973,{"v":9.58607532195122e-115,"d":"9.59E-115"},"*",{"v":4.92086e-117,"d":"4.92E-117"},"MT2A","NA","NA","NA","K14739//metallothionein 1/2","XP_007981228.1//PREDICTED: metallothionein-2-like [Chlorocebus sabaeus]",4]
[7538,1752,121.87,205.39,0.75302291146953,{"v":1.59893069538462e-102,"d":"1.60E-102"},"*",{"v":9.10872e-105,"d":"9.11E-105"},"ZFP36","GO:0010494//cytoplasmic stress granule;GO:0005634//nucleus;GO:0000932//P-body;GO:0005737//cytoplasm;GO:0030014//CCR4-NOT complex;GO:1990904//ribonucleoprotein complex;GO:0005829//cytosol;GO:0030529//intracellular ribonucleoprotein complex","GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003677//DNA binding;GO:0017091//AU-rich element binding;GO:0031072//heat shock protein binding;GO:0019957//C-C chemokine binding;GO:0019901//protein kinase binding;GO:0071889//14-3-3 protein binding;GO:0046872//metal ion binding;GO:0070063//RNA polymerase binding;GO:0035925//mRNA 3'-UTR AU-rich region binding;GO:0019899//enzyme binding;GO:0003727//single-stranded RNA binding","GO:0038066//p38MAPK cascade;GO:0010837//regulation of keratinocyte proliferation;GO:0071222//cellular response to lipopolysaccharide;GO:0032680//regulation of tumor necrosis factor production;GO:0071356//cellular response to tumor necrosis factor;GO:0050728//negative regulation of inflammatory response;GO:1900153//positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0051028//mRNA transport;GO:1902172//regulation of keratinocyte apoptotic process;GO:0032897//negative regulation of viral transcription;GO:0031086//nuclear-transcribed mRNA catabolic process, deadenylation-independent decay;GO:0045647//negative regulation of erythrocyte differentiation;GO:0009611//response to wounding;GO:0045600//positive regulation of fat cell differentiation;GO:1904582//positive regulation of intracellular mRNA localization;GO:0070935//3'-UTR-mediated mRNA stabilization;GO:1904246//negative regulation of polynucleotide adenylyltransferase activity;GO:0071385//cellular response to glucocorticoid stimulus;GO:0045638//negative regulation of myeloid cell differentiation;GO:0045085//negative regulation of interleukin-2 biosynthetic process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0043488//regulation of mRNA stability;GO:1901835//positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA;GO:0000165//MAPK cascade;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0006402//mRNA catabolic process;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0061158//3'-UTR-mediated mRNA destabilization;GO:0045616//regulation of keratinocyte differentiation;GO:0042594//response to starvation;GO:0060213//positive regulation of nuclear-transcribed mRNA poly(A) tail shortening;GO:2000637//positive regulation of gene silencing by miRNA;GO:0035278//miRNA mediated inhibition of translation;GO:0097011//cellular response to granulocyte macrophage colony-stimulating factor stimulus","K15308//tristetraprolin","NP_003398.2//mRNA decay activator protein ZFP36 [Homo sapiens]","3//A2MP1"]
[7766,2419,0.63,1.06,0.750640531063283,0.139035176745354,"*",0.0693174,"ZNF223","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","AAF18684.1//ZNF155 [Homo sapiens]",5]
[107080638,2351,0.47,0.79,0.749191896499466,0.185211931054131,"*",0.0976728,"TBC1D7-LOC100130357","GO:0036064//ciliary basal body;GO:0031410//cytoplasmic vesicle","GO:0017137//Rab GTPase binding;GO:0005096//GTPase activator activity","GO:0032007//negative regulation of TOR signaling;GO:0090630//activation of GTPase activity;GO:0070848//response to growth factor;GO:0031398//positive regulation of protein ubiquitination;GO:1902018//negative regulation of cilium assembly","K20396//TBC1 domain family member 7","XP_003263567.1//PREDICTED: TBC1 domain family member 7 isoform X2 [Nomascus leucogenys]","1//3"]
[51330,1048,217.24,364.95,0.748409052622747,{"v":1.04964966070588E-105,"d":"1.05E-105"},"*",{"v":5.58534e-108,"d":"5.59E-108"},"TNFRSF12A","GO:0001726//ruffle;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","NA","GO:0097191//extrinsic apoptotic signaling pathway;GO:0001525//angiogenesis;GO:0061041//regulation of wound healing;GO:0045773//positive regulation of axon extension;GO:0006931//substrate-dependent cell migration, cell attachment to substrate;GO:0043065//positive regulation of apoptotic process;GO:0045765//regulation of angiogenesis;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:0033209//tumor necrosis factor-mediated signaling pathway","K05149//tumor necrosis factor receptor superfamily member 12A","XP_016784722.1//PREDICTED: tumor necrosis factor receptor superfamily member 12A [Pan troglodytes]","2//1"]
[79663,1972,1.87,3.14,0.747726289003991,0.0139071861527729,"*",0.0049921,"HSPBAP1","GO:0005737//cytoplasm","NA","NA","K19375//HSPB1-associated protein 1","EHH16122.1//hypothetical protein EGK_11362 [Macaca mulatta];NP_078886.2//HSPB1-associated protein 1 isoform 1 [Homo sapiens]","1//3;5"]
[3669,1584,2.18,3.66,0.747515513507116,0.0672317804982206,"*",0.029567,"ISG20","GO:0016605//PML body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0015030//Cajal body;GO:0005737//cytoplasm","GO:0034511//U3 snoRNA binding;GO:0008310//single-stranded DNA 3'-5' exodeoxyribonuclease activity;GO:0000175//3'-5'-exoribonuclease activity;GO:0003676//nucleic acid binding;GO:0004527//exonuclease activity;GO:0046872//metal ion binding;GO:0030620//U2 snRNA binding;GO:0030619//U1 snRNA binding;GO:0008859//exoribonuclease II activity","GO:0006401//RNA catabolic process;GO:0060337//type I interferon signaling pathway;GO:0008283//cell proliferation;GO:0045071//negative regulation of viral genome replication;GO:0000738//DNA catabolic process, exonucleolytic;GO:0051607//defense response to virus;GO:0006364//rRNA processing;GO:0009615//response to virus","K12579//interferon-stimulated gene 20 kDa protein [EC:3.1.13.1]","NP_001290166.1//interferon-stimulated gene 20 kDa protein isoform c [Homo sapiens];NP_002192.2//interferon-stimulated gene 20 kDa protein isoform a [Homo sapiens];BAD92876.1//interferon stimulated gene 20kDa variant, partial [Homo sapiens]","1//3;5"]
[23645,2399,43.73,73.37,0.746566936740675,{"v":5.20276637575758e-50,"d":"5.20E-50"},"*",{"v":7.52372e-52,"d":"7.52E-52"},"PPP1R15A","GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0005741//mitochondrial outer membrane;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0000164//protein phosphatase type 1 complex;GO:0005789//endoplasmic reticulum membrane;GO:0005739//mitochondrion","GO:0019888//protein phosphatase regulator activity;GO:0072542//protein phosphatase activator activity;GO:0008157//protein phosphatase 1 binding;GO:0019901//protein kinase binding","GO:1903898//negative regulation of PERK-mediated unfolded protein response;GO:0032515//negative regulation of phosphoprotein phosphatase activity;GO:0034976//response to endoplasmic reticulum stress;GO:0007050//cell cycle arrest;GO:1990441//negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress;GO:0006974//cellular response to DNA damage stimulus;GO:0030968//endoplasmic reticulum unfolded protein response;GO:1902310//positive regulation of peptidyl-serine dephosphorylation;GO:0032516//positive regulation of phosphoprotein phosphatase activity;GO:0070972//protein localization to endoplasmic reticulum;GO:1903917//positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation;GO:0036496//regulation of translational initiation by eIF2 alpha dephosphorylation;GO:1903912//negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation;GO:0032058//positive regulation of translational initiation in response to stress;GO:0006915//apoptotic process;GO:0070262//peptidyl-serine dephosphorylation;GO:0035308//negative regulation of protein dephosphorylation;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0045943//positive regulation of transcription from RNA polymerase I promoter;GO:0060734//regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation","K14019//protein phosphatase 1 regulatory subunit 15A","NP_055145.3//protein phosphatase 1 regulatory subunit 15A [Homo sapiens]","3//A2MP1"]
[64859,3855,3.55,5.94,0.742643906408721,{"v":6.60559976991838e-07,"d":"6.61E-07"},"*",{"v":1.063992E-7,"d":"1.06E-07"},"NABP1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000784//nuclear chromosome, telomeric region;GO:0005829//cytosol;GO:0070876//SOSS complex","GO:0003697//single-stranded DNA binding;GO:0003723//RNA binding","GO:0007093//mitotic cell cycle checkpoint;GO:0042795//snRNA transcription from RNA polymerase II promoter;GO:0010212//response to ionizing radiation;GO:0006281//DNA repair;GO:0000724//double-strand break repair via homologous recombination;GO:0006974//cellular response to DNA damage stimulus","K15280//solute carrier family 35, member C2","NP_001026886.1//SOSS complex subunit B2 isoform 1 [Homo sapiens]","1//3;2//1"]
[715,2625,20.22,33.82,0.742093662506969,{"v":6.85612052762923e-25,"d":"6.86E-25"},"*",{"v":2.40784e-26,"d":"2.41E-26"},"C1R","NA","NA","NA","K01330//complement component 1, r subcomponent [EC:3.4.21.41]","NP_001341275.1//complement C1r subcomponent isoform 2 preproprotein [Homo sapiens];NP_001724.4//complement C1r subcomponent isoform 1 preproprotein [Homo sapiens]","1//3;5"]
[373156,1113,82.21,137.46,0.741626065786125,{"v":7.83226055652174e-47,"d":"7.83E-47"},"*",{"v":1.240492E-48,"d":"1.24E-48"},"GSTK1","GO:0005759//mitochondrial matrix;GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005743//mitochondrial inner membrane;GO:0005622//intracellular;GO:0005777//peroxisome","GO:0015035//protein disulfide oxidoreductase activity;GO:0004364//glutathione transferase activity;GO:0004602//glutathione peroxidase activity;GO:0016740//transferase activity;GO:0005102//receptor binding","GO:0006749//glutathione metabolic process;GO:1901687//glutathione derivative biosynthetic process;GO:0030855//epithelial cell differentiation","K13299//glutathione S-transferase kappa 1 [EC:2.5.1.18]","NP_057001.1//glutathione S-transferase kappa 1 isoform a [Homo sapiens];NP_001137153.1//glutathione S-transferase kappa 1 isoform d [Homo sapiens];NP_001137151.1//glutathione S-transferase kappa 1 isoform b [Homo sapiens];NP_001137152.1//glutathione S-transferase kappa 1 isoform c [Homo sapiens]","1//3;2//1"]
[6722,3630,16.09,26.85,0.738757762149329,{"v":3.82665924721754e-24,"d":"3.83E-24"},"*",{"v":1.420564E-25,"d":"1.42E-25"},"SRF","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000790//nuclear chromatin;GO:0005737//cytoplasm","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0001076//transcription factor activity, RNA polymerase II transcription factor binding;GO:0070878//primary miRNA binding;GO:0042826//histone deacetylase binding;GO:0031490//chromatin DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0000983//transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding;GO:0003705//transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding;GO:0010736//serum response element binding;GO:0042803//protein homodimerization activity;GO:0046983//protein dimerization activity;GO:0000982//transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0000987//proximal promoter sequence-specific DNA binding;GO:0008134//transcription factor binding","GO:1902895//positive regulation of pri-miRNA transcription from RNA polymerase II promoter;GO:0021766//hippocampus development;GO:0060055//angiogenesis involved in wound healing;GO:0060534//trachea cartilage development;GO:0030878//thyroid gland development;GO:0060292//long term synaptic depression;GO:0008285//negative regulation of cell proliferation;GO:0022028//tangential migration from the subventricular zone to the olfactory bulb;GO:0007160//cell-matrix adhesion;GO:0071333//cellular response to glucose stimulus;GO:0001764//neuron migration;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0001569//branching involved in blood vessel morphogenesis;GO:0055003//cardiac myofibril assembly;GO:0034097//response to cytokine;GO:0030168//platelet activation;GO:0090009//primitive streak formation;GO:0045773//positive regulation of axon extension;GO:0001707//mesoderm formation;GO:0048821//erythrocyte development;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0090398//cellular senescence;GO:0030220//platelet formation;GO:1900222//negative regulation of amyloid-beta clearance;GO:0060218//hematopoietic stem cell differentiation;GO:0045214//sarcomere organization;GO:0060947//cardiac vascular smooth muscle cell differentiation;GO:0006351//transcription, DNA-templated;GO:0001701//in utero embryonic development;GO:0046716//muscle cell cellular homeostasis;GO:0045059//positive thymic T cell selection;GO:0043149//stress fiber assembly;GO:0043589//skin morphogenesis;GO:0060425//lung morphogenesis;GO:0001829//trophectodermal cell differentiation;GO:0060324//face development;GO:0003257//positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation;GO:0045597//positive regulation of cell differentiation;GO:0090136//epithelial cell-cell adhesion;GO:0035912//dorsal aorta morphogenesis;GO:0001666//response to hypoxia;GO:0045987//positive regulation of smooth muscle contraction;GO:0060532//bronchus cartilage development;GO:0010735//positive regulation of transcription via serum response element binding;GO:0070830//bicellular tight junction assembly;GO:0010669//epithelial structure maintenance;GO:1902894//negative regulation of pri-miRNA transcription from RNA polymerase II promoter;GO:0046016//positive regulation of transcription by glucose;GO:0042789//mRNA transcription from RNA polymerase II promoter;GO:0007616//long-term memory;GO:0002011//morphogenesis of an epithelial sheet;GO:0002042//cell migration involved in sprouting angiogenesis;GO:0031175//neuron projection development;GO:0030155//regulation of cell adhesion;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter;GO:0035855//megakaryocyte development;GO:0051491//positive regulation of filopodium assembly;GO:0061029//eyelid development in camera-type eye;GO:0048538//thymus development;GO:0030336//negative regulation of cell migration;GO:0061145//lung smooth muscle development;GO:0001947//heart looping;GO:0008306//associative learning;GO:0033561//regulation of water loss via skin;GO:0060347//heart trabecula formation;GO:0048589//developmental growth;GO:0009725//response to hormone","K04378//serum response factor","XP_017733675.1//PREDICTED: serum response factor isoform X2 [Rhinopithecus bieti];NP_003122.1//serum response factor isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[55080,1834,2.5,4.17,0.738119288782576,0.0059352121703916,"*",1.945088E-3,"TAPBPL","GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0000139//Golgi membrane","GO:0032403//protein complex binding","GO:0002376//immune system process;GO:0002590//negative regulation of antigen processing and presentation of peptide antigen via MHC class I","K08058//TAP binding protein (tapasin)","NP_060479.3//tapasin-related protein precursor [Homo sapiens]","4;1//3"]
[7975,3350,30.35,50.62,0.738010990967639,{"v":1.54782865203252e-47,"d":"1.55E-47"},"*",{"v":2.38366e-49,"d":"2.38E-49"},"MAFK","NA","NA","NA","K09037//transcription factor MAFF/G/K","XP_014201039.1//PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein LOC106634934 [Pan paniscus]","3//A2MP1"]
[2814,3493,0.06,0.1,0.736965594166206,0.609452303506548,"*",0.451538,"GP5","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005578//proteinaceous extracellular matrix","NA","GO:0007155//cell adhesion;GO:0007596//blood coagulation;GO:0007597//blood coagulation, intrinsic pathway;GO:0030168//platelet activation;GO:0007409//axonogenesis","K06260//platelet glycoprotein V","NP_004479.1//platelet glycoprotein V precursor [Homo sapiens]","2//1"]
[320,6603,0.06,0.1,0.736965594166206,0.57888458556701,"*",0.421824,"APBA1","GO:0016020//membrane;GO:0005634//nucleus;GO:0008021//synaptic vesicle;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm;GO:0043005//neuron projection","GO:0001540//amyloid-beta binding","GO:0007399//nervous system development;GO:0010468//regulation of gene expression;GO:0008088//axo-dendritic transport;GO:0001701//in utero embryonic development;GO:0014051//gamma-aminobutyric acid secretion;GO:0035264//multicellular organism growth;GO:0006886//intracellular protein transport;GO:0007269//neurotransmitter secretion;GO:0007155//cell adhesion;GO:0007626//locomotory behavior;GO:0007268//chemical synaptic transmission;GO:0006461//protein complex assembly;GO:0014047//glutamate secretion","K04531//amyloid beta A4 precursor protein-binding family A member 1","NP_001154.2//amyloid beta A4 precursor protein-binding family A member 1 [Homo sapiens]","3//A2MP1"]
[246176,3031,0.03,0.05,0.736965594166206,0.735313432157094,"*",0.623548,"GAS2L2","GO:0005856//cytoskeleton;GO:0005737//cytoplasm","GO:0051015//actin filament binding;GO:0008017//microtubule binding;GO:0008093//cytoskeletal adaptor activity","GO:0007026//negative regulation of microtubule depolymerization;GO:0001578//microtubule bundle formation","K17953//cytochrome P450 family 31 subfamily A;K10382//dystonin;K13209//RNA-binding protein EWS","NP_644814.1//GAS2-like protein 2 [Homo sapiens]","3//A2MP1"]
[100130742,1323,0.06,0.1,0.736965594166206,1.00655049864328,"*",0.998548,"LRRC69","NA","NA","NA","K18342//OTU domain-containing protein 6 [EC:3.4.19.12];K16175//protein scribble","NP_001123362.1//leucine-rich repeat-containing protein 69 isoform 1 [Homo sapiens];NP_001341399.1//leucine-rich repeat-containing protein 69 isoform 2 [Homo sapiens]","1//3"]
[89874,3947,0.3,0.5,0.736965594166206,0.717857193865396,"*",0.603622,"SLC25A21","GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane","GO:0005310//dicarboxylic acid transmembrane transporter activity;GO:0015139//alpha-ketoglutarate transmembrane transporter activity","GO:0055085//transmembrane transport;GO:0006835//dicarboxylic acid transport;GO:0006554//lysine catabolic process;GO:0006839//mitochondrial transport","K15110//solute carrier family 25 (mitochondrial 2-oxodicarboxylate transporter), member 21","NP_001164641.1//mitochondrial 2-oxodicarboxylate carrier isoform 2 [Homo sapiens];NP_085134.1//mitochondrial 2-oxodicarboxylate carrier isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[51294,6579,0.06,0.1,0.736965594166206,0.578685724493301,"*",0.421824,"PCDH12","GO:0070062//extracellular exosome;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0005886//plasma membrane","GO:0005509//calcium ion binding","GO:0060711//labyrinthine layer development;GO:0005977//glycogen metabolic process;GO:0007155//cell adhesion;GO:0008038//neuron recognition;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007267//cell-cell signaling;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules","K16499//protocadherin delta 2","NP_057664.1//protocadherin-12 precursor [Homo sapiens]","3//A2MP1"]
[51351,6404,0.12,0.2,0.736965594166206,0.28755918832274,"*",0.1671098,"ZNF117","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_018886338.1//PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 107-like [Gorilla gorilla gorilla]","3//A2MP1"]
[164312,2982,0.03,0.05,0.736965594166206,0.733472441237113,"*",0.623548,"LRRN4","GO:0070062//extracellular exosome;GO:0005887//integral component of plasma membrane","NA","GO:0008542//visual learning;GO:0007616//long-term memory","K16360//netrin-G3 ligand","NP_689824.2//leucine-rich repeat neuronal protein 4 precursor [Homo sapiens]",4]
[5156,4004,0.03,0.05,0.736965594166206,1.0111605819012,"*",0.998184,"PDGFRA","GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0030054//cell junction;GO:0005737//cytoplasm","GO:0048407//platelet-derived growth factor binding;GO:0005524//ATP binding;GO:0005018//platelet-derived growth factor alpha-receptor activity;GO:0046934//phosphatidylinositol-4,5-bisphosphate 3-kinase activity","GO:0001775//cell activation;GO:0060326//cell chemotaxis;GO:0030325//adrenal gland development;GO:0055003//cardiac myofibril assembly","K04363//platelet-derived growth factor receptor alpha [EC:2.7.10.1]","NP_001334759.1//platelet-derived growth factor receptor alpha isoform 4 [Homo sapiens];NP_001334757.1//platelet-derived growth factor receptor alpha isoform 3 [Homo sapiens];XP_006714104.1//PREDICTED: platelet-derived growth factor receptor alpha isoform X4 [Homo sapiens]","1//3;5"]
[10418,5154,0.03,0.05,0.736965594166206,0.780639167842634,"*",0.685686,"SPON1","NA","NA","NA","K13912//deleted in malignant brain tumors 1 protein;K16857//thrombospondin 1","XP_508295.3//PREDICTED: spondin-1 [Pan troglodytes]","3//A2MP1"]
[347688,1504,0.03,0.05,0.736965594166206,0.641572407887324,"*",0.499032,"TUBB8","GO:0005874//microtubule;GO:0005737//cytoplasm","GO:0005200//structural constituent of cytoskeleton;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0007017//microtubule-based process","K07375//tubulin beta","A6NNZ2.1//RecName: Full=Tubulin beta-8 chain-like protein LOC260334","2//1"]
[51440,4670,0.03,0.05,0.736965594166206,0.780305490061979,"*",0.685686,"HPCAL4","NA","GO:0005509//calcium ion binding;GO:0005246//calcium channel regulator activity","GO:0007165//signal transduction","K19936//visinin-like protein 1","XP_010624191.1//PREDICTED: hippocalcin-like protein 4 isoform X1 [Fukomys damarensis];OXB56417.1//hypothetical protein ASZ78_010671, partial [Callipepla squamata];NP_001269326.1//hippocalcin-like protein 4 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[23166,7965,0.03,0.05,0.736965594166206,0.628509440970602,"*",0.505908,"STAB1","NA","NA","NA","K19020//stabilin-1","XP_005265031.1//PREDICTED: stabilin-1 isoform X6 [Homo sapiens]","2//1"]
[27033,2108,0.27,0.45,0.736965594166206,1.018769645087,"*",0.996958,"ZBTB32","GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0008270//zinc ion binding;GO:0003676//nucleic acid binding","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0042769//DNA damage response, detection of DNA damage;GO:0036297//interstrand cross-link repair;GO:0006366//transcription from RNA polymerase II promoter","K10506//zinc finger and BTB domain-containing protein 32","XP_016882081.1//PREDICTED: zinc finger and BTB domain-containing protein 32 isoform X5 [Homo sapiens];NP_001303831.1//zinc finger and BTB domain-containing protein 32 isoform 2 [Homo sapiens];NP_055198.1//zinc finger and BTB domain-containing protein 32 isoform 1 [Homo sapiens]","1//3;2//1"]
[58512,3856,0.21,0.35,0.736965594166206,0.309439972005497,"*",0.1832348,"DLGAP3","GO:0030054//cell junction;GO:0045202//synapse;GO:0014069//postsynaptic density;GO:0005886//plasma membrane;GO:0045211//postsynaptic membrane","GO:0001540//amyloid-beta binding;GO:0019904//protein domain specific binding","GO:0023052//signaling;GO:0006461//protein complex assembly","K15008//discs, large-associated protein 1","NP_001073887.1//disks large-associated protein 3 [Homo sapiens]","2//1"]
[57593,2931,0.98,1.63,0.734018310115869,0.0347613091304348,"*",0.0140142,"EBF4","GO:0005634//nucleus","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0008134//transcription factor binding","GO:0007275//multicellular organism development","K09103//early B-cell factor","XP_017360238.1//PREDICTED: transcription factor COE4 isoform X1 [Cebus capucinus imitator]","1//3"]
[116986,4957,4.17,6.93,0.73280796869255,{"v":8.9426898647289e-10,"d":"8.94E-10"},"*",{"v":1.001532E-10,"d":"1.00E-10"},"AGAP2","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005739//mitochondrion","GO:0046872//metal ion binding;GO:0030295//protein kinase activator activity;GO:0005525//GTP binding;GO:0019901//protein kinase binding;GO:0003924//GTPase activity;GO:0005096//GTPase activator activity","GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0042177//negative regulation of protein catabolic process;GO:0043524//negative regulation of neuron apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0046427//positive regulation of JAK-STAT cascade;GO:0060749//mammary gland alveolus development;GO:0033601//positive regulation of mammary gland epithelial cell proliferation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0015031//protein transport","K17848//Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2","NP_055585.1//arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 isoform PIKE-A [Homo sapiens];NP_001116244.1//arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 isoform PIKE-L [Homo sapiens]","3//A2MP1;2//1"]
[83938,857,2.04,3.39,0.732716121164849,0.126870976576577,"*",0.061712,"LRMDA","NA","NA","GO:0030318//melanocyte differentiation","K11092//U2 small nuclear ribonucleoprotein A'","XP_015002715.1//PREDICTED: leucine-rich repeat-containing protein C10orf11 homolog [Macaca mulatta];NP_114413.1//leucine-rich melanocyte differentiation-associated protein isoform 2 [Homo sapiens]","1//3;4"]
[1482,1760,10.46,17.34,0.729221046974894,{"v":5.81545084205817e-08,"d":"5.82E-08"},"*",{"v":8.13668e-09,"d":"8.14E-09"},"NKX2-5","GO:0090575//RNA polymerase II transcription factor complex;GO:0032991//macromolecular complex;GO:0005634//nucleus;GO:0005667//transcription factor complex;GO:0032993//protein-DNA complex;GO:0005737//cytoplasm","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0046982//protein heterodimerization activity;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003705//transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding;GO:0010736//serum response element binding;GO:0042803//protein homodimerization activity;GO:0001190//transcriptional activator activity, RNA polymerase II transcription factor binding;GO:0003682//chromatin binding;GO:0043565//sequence-specific DNA binding;GO:0008134//transcription factor binding","GO:0003148//outflow tract septum morphogenesis;GO:0060412//ventricular septum morphogenesis;GO:0045666//positive regulation of neuron differentiation;GO:0010667//negative regulation of cardiac muscle cell apoptotic process;GO:0007512//adult heart development;GO:0051891//positive regulation of cardioblast differentiation;GO:0003211//cardiac ventricle formation;GO:0030878//thyroid gland development;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0060048//cardiac muscle contraction;GO:0001570//vasculogenesis;GO:0003166//bundle of His development;GO:0010832//negative regulation of myotube differentiation;GO:0003221//right ventricular cardiac muscle tissue morphogenesis;GO:0060037//pharyngeal system development;GO:0055014//atrial cardiac muscle cell development;GO:0060928//atrioventricular node cell development;GO:0055117//regulation of cardiac muscle contraction;GO:0030509//BMP signaling pathway;GO:0010765//positive regulation of sodium ion transport;GO:0003151//outflow tract morphogenesis;GO:0003285//septum secundum development;GO:0010735//positive regulation of transcription via serum response element binding;GO:0060070//canonical Wnt signaling pathway;GO:0003168//Purkinje myocyte differentiation;GO:0003222//ventricular trabecula myocardium morphogenesis;GO:0060038//cardiac muscle cell proliferation;GO:0048536//spleen development;GO:0060971//embryonic heart tube left/right pattern formation;GO:0030097//hemopoiesis;GO:0060043//regulation of cardiac muscle cell proliferation;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter;GO:1903779//regulation of cardiac conduction;GO:0003350//pulmonary myocardium development;GO:0045214//sarcomere organization;GO:0060929//atrioventricular node cell fate commitment;GO:0003278//apoptotic process involved in heart morphogenesis;GO:0045823//positive regulation of heart contraction;GO:0055005//ventricular cardiac myofibril assembly;GO:0001947//heart looping;GO:0060413//atrial septum morphogenesis;GO:0003342//proepicardium development;GO:0060347//heart trabecula formation;GO:0008284//positive regulation of cell proliferation","K09345//homeobox protein Nkx-2.5","XP_004697192.1//PREDICTED: homeobox protein Nkx-2.5 [Echinops telfairi];NP_004378.1//homeobox protein Nkx-2.5 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[9997,1030,19.16,31.76,0.729113351406778,{"v":3.11148660357518e-09,"d":"3.11E-09"},"*",{"v":3.7048E-10,"d":"3.70E-10"},"SCO2","GO:0005759//mitochondrial matrix;GO:0005743//mitochondrial inner membrane;GO:0030016//myofibril;GO:0005739//mitochondrion","GO:0005507//copper ion binding","GO:0003012//muscle system process;GO:0001654//eye development;GO:0006878//cellular copper ion homeostasis;GO:0014823//response to activity;GO:0001701//in utero embryonic development;GO:0008535//respiratory chain complex IV assembly;GO:0055114//oxidation-reduction process;GO:0006825//copper ion transport;GO:0045454//cell redox homeostasis;GO:0022904//respiratory electron transport chain","K07152//protein SCO1/2","XP_001116350.3//PREDICTED: protein SCO2 homolog, mitochondrial [Macaca mulatta];XP_011753064.1//PREDICTED: uncharacterized protein LOC105489744 isoform X1 [Macaca nemestrina];NP_005129.2//protein SCO2 homolog, mitochondrial precursor [Homo sapiens]","1//3;2//1"]
[51284,4992,0.49,0.81,0.725140158769417,0.0618302896333573,"*",0.0269206,"TLR7","GO:0016021//integral component of membrane","GO:0004888//transmembrane signaling receptor activity;GO:0003727//single-stranded RNA binding","GO:0034154//toll-like receptor 7 signaling pathway;GO:0051607//defense response to virus;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0045087//innate immune response","K05404//toll-like receptor 7","AAZ99026.1//TLR7 [Homo sapiens]","3//A2MP1"]
[7706,5744,15.62,25.78,0.722857810219672,{"v":2.55935534849498e-40,"d":"2.56E-40"},"*",{"v":4.79058e-42,"d":"4.79E-42"},"TRIM25","GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0005829//cytosol","GO:0003723//RNA binding;GO:0008270//zinc ion binding;GO:1904264//ubiquitin protein ligase activity involved in ERAD pathway;GO:0003700//DNA binding transcription factor activity;GO:0004842//ubiquitin-protein transferase activity;GO:0016874//ligase activity;GO:0045296//cadherin binding","GO:0046597//negative regulation of viral entry into host cell;GO:0043627//response to estrogen;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0036503//ERAD pathway;GO:0016579//protein deubiquitination;GO:0045087//innate immune response;GO:0060333//interferon-gamma-mediated signaling pathway;GO:1902186//regulation of viral release from host cell;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0006513//protein monoubiquitination;GO:0051607//defense response to virus;GO:1902187//negative regulation of viral release from host cell;GO:0016032//viral process;GO:0033280//response to vitamin D;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0019985//translesion synthesis;GO:1990830//cellular response to leukemia inhibitory factor;GO:0046596//regulation of viral entry into host cell;GO:0032480//negative regulation of type I interferon production","K10652//tripartite motif-containing protein 25 [EC:2.3.2.27]","BAD92231.1//tripartite motif-containing 25 variant, partial [Homo sapiens]",4]
[8416,1843,0.74,1.22,0.721283971933937,0.192719564000471,"*",0.1024162,"ANXA9","GO:0070062//extracellular exosome;GO:0009986//cell surface;GO:0005829//cytosol","GO:0005544//calcium-dependent phospholipid binding;GO:0005509//calcium ion binding;GO:0001786//phosphatidylserine binding;GO:0015464//acetylcholine receptor activity","GO:0098609//cell-cell adhesion","K17090//annexin A9","XP_017401806.1//PREDICTED: annexin A9 isoform X1 [Cebus capucinus imitator]","2//1"]
[150696,4719,0.91,1.5,0.721024050297185,0.0113627323252496,"*",0.00398912,"PROM2","GO:0071914//prominosome;GO:0070062//extracellular exosome;GO:0009986//cell surface;GO:0042995//cell projection;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","NA","GO:0043087//regulation of GTPase activity;GO:0001934//positive regulation of protein phosphorylation;GO:0031346//positive regulation of cell projection organization;GO:0048550//negative regulation of pinocytosis;GO:2001287//negative regulation of caveolin-mediated endocytosis","K15602//prominin 2","AAM10541.1//prominin-2 variant A [Homo sapiens]","1//3;3//A2MP1;2//1"]
[144110,3676,0.17,0.28,0.719892080807265,0.430093442970822,"*",0.284216,"TMEM86A","GO:0016021//integral component of membrane","NA","NA","K18575//alkenylglycerophosphocholine hydrolase [EC:3.3.2.2]","XP_004415708.2//PREDICTED: LOW QUALITY PROTEIN: lysoplasmalogenase-like protein TMEM86A [Odobenus rosmarus divergens]","2//1"]
[2859,1656,0.34,0.56,0.719892080807265,0.176879162352941,"*",0.0922376,"GPR35","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004930//G-protein coupled receptor activity;GO:0016494//C-X-C chemokine receptor activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway;GO:0070098//chemokine-mediated signaling pathway;GO:1901386//negative regulation of voltage-gated calcium channel activity;GO:0035025//positive regulation of Rho protein signal transduction;GO:0007010//cytoskeleton organization;GO:1904456//negative regulation of neuronal action potential;GO:0007204//positive regulation of cytosolic calcium ion concentration","K04276//G protein-coupled receptor 35","NP_001182310.1//G-protein coupled receptor 35 isoform b [Homo sapiens];XP_003813126.1//PREDICTED: G-protein coupled receptor 35 isoform X1 [Pan paniscus]","1//3;3//A2MP1"]
[9564,4132,44.68,73.51,0.718311335815838,{"v":3.22811351935484e-80,"d":"3.23E-80"},"*",{"v":2.50586e-82,"d":"2.51E-82"},"BCAR1","GO:0001726//ruffle;GO:0005925//focal adhesion;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0005886//plasma membrane;GO:0030027//lamellipodium;GO:0005737//cytoplasm","GO:0004871//signal transducer activity;GO:0017124//SH3 domain binding;GO:0019901//protein kinase binding","GO:0016477//cell migration;GO:0030335//positive regulation of cell migration;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0008286//insulin receptor signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0010595//positive regulation of endothelial cell migration;GO:0048012//hepatocyte growth factor receptor signaling pathway;GO:0007015//actin filament organization;GO:0008283//cell proliferation;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0060326//cell chemotaxis;GO:0007229//integrin-mediated signaling pathway;GO:0001558//regulation of cell growth;GO:0050853//B cell receptor signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway;GO:0035729//cellular response to hepatocyte growth factor stimulus;GO:0050852//T cell receptor signaling pathway;GO:0007155//cell adhesion;GO:0051301//cell division;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0042981//regulation of apoptotic process;GO:0050851//antigen receptor-mediated signaling pathway","K05726//breast cancer anti-estrogen resistance 1","NP_001164189.1//breast cancer anti-estrogen resistance protein 1 isoform 5 [Homo sapiens];NP_001164187.1//breast cancer anti-estrogen resistance protein 1 isoform 3 [Homo sapiens];NP_001164186.1//breast cancer anti-estrogen resistance protein 1 isoform 2 [Homo sapiens];NP_001164185.1//breast cancer anti-estrogen resistance protein 1 isoform 1 [Homo sapiens];XP_007992273.1//PREDICTED: breast cancer anti-estrogen resistance protein 1 isoform X1 [Chlorocebus sabaeus];NP_001164190.1//breast cancer anti-estrogen resistance protein 1 isoform 7 [Homo sapiens];NP_001164191.1//breast cancer anti-estrogen resistance protein 1 isoform 8 [Homo sapiens]","4;2//1"]
[100128071,716,2,3.29,0.718087583960517,0.192742268944392,"*",0.1024162,"FAM229A","NA","NA","NA","NA","NP_001161148.1//protein FAM229A [Homo sapiens]","1//3"]
[5348,575,0.45,0.74,0.717600269299275,0.62894967639505,"*",0.505908,"FXYD1","GO:0042383//sarcolemma;GO:0016021//integral component of membrane","GO:0005216//ion channel activity;GO:0017080//sodium channel regulator activity","GO:2000649//regulation of sodium ion transmembrane transporter activity;GO:1903278//positive regulation of sodium ion export across plasma membrane;GO:0086036//regulation of cardiac muscle cell membrane potential","K13363//FXYD domain-containing ion transport regulator 6;K13360//FXYD domain-containing ion transport regulator 1","XP_002920972.1//PREDICTED: phospholemman [Ailuropoda melanoleuca]","1//3;4;3//A2MP1"]
[6876,3882,4.56,7.49,0.715931894294009,{"v":3.17783502037037e-08,"d":"3.18E-08"},"*",{"v":4.29706e-09,"d":"4.30E-09"},"TAGLN","GO:0005737//cytoplasm","GO:0051015//actin filament binding","GO:0007517//muscle organ development;GO:0030855//epithelial cell differentiation","K20526//transgelin","EAW67300.1//transgelin, isoform CRA_c [Homo sapiens]","4;2//1"]
[26353,2056,7.49,12.29,0.714447291913911,{"v":2.42966979281882e-07,"d":"2.43E-07"},"*",{"v":3.68542e-08,"d":"3.69E-08"},"HSPB8","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005737//cytoplasm","GO:0042802//identical protein binding","GO:1900034//regulation of cellular response to heat","K08879//heat shock protein beta-8","NP_055180.1//heat shock protein beta-8 [Homo sapiens]","2//1"]
[9746,4029,13.6,22.31,0.714083862106439,{"v":3.57067469594595e-24,"d":"3.57E-24"},"*",{"v":1.3233e-25,"d":"1.32E-25"},"CLSTN3","GO:0070062//extracellular exosome;GO:0009986//cell surface;GO:0043234//protein complex;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0014069//postsynaptic density;GO:0045211//postsynaptic membrane;GO:0000139//Golgi membrane","GO:0005509//calcium ion binding","GO:0001558//regulation of cell growth;GO:0050806//positive regulation of synaptic transmission;GO:1902474//positive regulation of protein localization to synapse;GO:0051965//positive regulation of synapse assembly;GO:0007416//synapse assembly;GO:0051932//synaptic transmission, GABAergic;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0035249//synaptic transmission, glutamatergic","K04601//cadherin EGF LAG seven-pass G-type receptor 2;K16494//protocadherin beta","XP_017747257.1//PREDICTED: calsyntenin-3 isoform X1 [Rhinopithecus bieti]","3//A2MP1"]
[9744,2523,0.25,0.41,0.713695814843359,0.430052702851189,"*",0.284216,"ACAP1","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0055038//recycling endosome membrane","GO:0046872//metal ion binding;GO:0005096//GTPase activator activity","GO:0015031//protein transport","K12489//Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein","XP_008994854.2//PREDICTED: arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 isoform X1 [Callithrix jacchus]","3//A2MP1"]
[634,3393,0.75,1.23,0.713695814843359,0.0526038324776295,"*",0.022449,"CEACAM1","GO:0030658//transport vesicle membrane;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0030054//cell junction;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0016021//integral component of membrane;GO:0016328//lateral plasma membrane;GO:0070821//tertiary granule membrane;GO:0005886//plasma membrane;GO:0070062//extracellular exosome;GO:0005912//adherens junction;GO:0009925//basal plasma membrane;GO:0009986//cell surface;GO:0035579//specific granule membrane;GO:0031528//microvillus membrane","GO:1990782//protein tyrosine kinase binding;GO:0019903//protein phosphatase binding;GO:0042803//protein homodimerization activity;GO:0046983//protein dimerization activity;GO:0003779//actin binding;GO:0015125//bile acid transmembrane transporter activity;GO:0019900//kinase binding;GO:0005516//calmodulin binding;GO:0031005//filamin binding","GO:1903670//regulation of sprouting angiogenesis;GO:1901143//insulin catabolic process;GO:0016477//cell migration;GO:0001568//blood vessel development;GO:0015721//bile acid and bile salt transport;GO:0050860//negative regulation of T cell receptor signaling pathway;GO:0030853//negative regulation of granulocyte differentiation;GO:0043116//negative regulation of vascular permeability;GO:0001915//negative regulation of T cell mediated cytotoxicity;GO:1903385//regulation of homophilic cell adhesion;GO:0010594//regulation of endothelial cell migration;GO:0090331//negative regulation of platelet aggregation;GO:0001558//regulation of cell growth;GO:0038016//insulin receptor internalization;GO:0002859//negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target;GO:0001525//angiogenesis;GO:0014066//regulation of phosphatidylinositol 3-kinase signaling;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0035726//common myeloid progenitor cell proliferation;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0051055//negative regulation of lipid biosynthetic process;GO:2000346//negative regulation of hepatocyte proliferation;GO:0032692//negative regulation of interleukin-1 production;GO:0030334//regulation of cell migration;GO:0007229//integrin-mediated signaling pathway;GO:0043312//neutrophil degranulation;GO:0045601//regulation of endothelial cell differentiation;GO:0044319//wound healing, spreading of cells;GO:0038158//granulocyte colony-stimulating factor signaling pathway;GO:0043318//negative regulation of cytotoxic T cell degranulation;GO:0050900//leukocyte migration;GO:2001214//positive regulation of vasculogenesis;GO:0060312//regulation of blood vessel remodeling;GO:0032869//cellular response to insulin stimulus;GO:0006469//negative regulation of protein kinase activity;GO:0045717//negative regulation of fatty acid biosynthetic process;GO:0098742//cell-cell adhesion via plasma-membrane adhesion molecules;GO:0042058//regulation of epidermal growth factor receptor signaling pathway","K06499//carcinoembryonic antigen-related cell adhesion molecule","XP_004060901.2//PREDICTED: carcinoembryonic antigen-related cell adhesion molecule 1 isoform X2 [Gorilla gorilla gorilla];NP_001703.2//carcinoembryonic antigen-related cell adhesion molecule 1 isoform 1 precursor [Homo sapiens];NP_001171744.1//carcinoembryonic antigen-related cell adhesion molecule 1 isoform 3 precursor [Homo sapiens]","4;1//3;2//1"]
[283212,1952,0.25,0.41,0.713695814843359,0.482415676328061,"*",0.330298,"KLHL35","GO:0031463//Cul3-RING ubiquitin ligase complex","NA","GO:0016567//protein ubiquitination","K10461//kelch-like protein 24/35","XP_011543256.1//PREDICTED: kelch-like protein 35 isoform X1 [Homo sapiens]","2//1"]
[132158,3798,2.07,3.38,0.707392478782859,2.642074640625E-3,"*",0.000804498,"GLYCTK","GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005737//cytoplasm","GO:0005524//ATP binding;GO:0008887//glycerate kinase activity","GO:0061624//fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate;GO:0006468//protein phosphorylation","K11529//glycerate 2-kinase [EC:2.7.1.165]","NP_660305.2//glycerate kinase isoform 1 [Homo sapiens];XP_016861219.1//PREDICTED: glycerate kinase isoform X1 [Homo sapiens]","1//3;3//A2MP1"]
[10410,678,30.87,50.37,0.706359248043061,{"v":4.57552427671657e-09,"d":"4.58E-09"},"*",{"v":5.54826E-10,"d":"5.55E-10"},"IFITM3","GO:0005765//lysosomal membrane;GO:0070062//extracellular exosome;GO:0031902//late endosome membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","NA","GO:0035456//response to interferon-beta;GO:0060337//type I interferon signaling pathway;GO:0051607//defense response to virus;GO:0046597//negative regulation of viral entry into host cell;GO:0035455//response to interferon-alpha;GO:0045071//negative regulation of viral genome replication;GO:0034341//response to interferon-gamma;GO:0006955//immune response;GO:0032897//negative regulation of viral transcription;GO:0009615//response to virus","K06566//interferon induced transmembrane protein","XP_007984939.1//PREDICTED: interferon-induced transmembrane protein 3 [Chlorocebus sabaeus]","2//1"]
[79669,2188,2.11,3.44,0.705165565994913,0.00915840720160848,"*",0.0031367,"C3orf52","GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","NA","NA","NA","NP_001165218.1//TPA-induced transmembrane protein isoform 1 [Homo sapiens];NP_078892.2//TPA-induced transmembrane protein isoform 2 [Homo sapiens]","1//3;2//1"]
[10161,2561,0.59,0.96,0.702319451359315,0.163463190181067,"*",0.084208,"LPAR6","GO:0043231//intracellular membrane-bounded organelle;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0070915//lysophosphatidic acid receptor activity;GO:0004930//G-protein coupled receptor activity","GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway;GO:0035025//positive regulation of Rho protein signal transduction","K04273//lysophosphatidic acid receptor 6","NP_005758.2//lysophosphatidic acid receptor 6 [Homo sapiens]","1//3;5"]
[3038,3810,22.79,37.08,0.702240319360234,{"v":2.55455537762238E-41,"d":"2.55E-41"},"*",{"v":4.5737e-43,"d":"4.57E-43"},"HAS3","GO:0005887//integral component of plasma membrane;GO:0036117//hyaluranon cable;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0050501//hyaluronan synthase activity","GO:0045226//extracellular polysaccharide biosynthetic process;GO:1900106//positive regulation of hyaluranon cable assembly;GO:0007155//cell adhesion;GO:0030213//hyaluronan biosynthetic process;GO:0085029//extracellular matrix assembly;GO:0005975//carbohydrate metabolic process;GO:0045893//positive regulation of transcription, DNA-templated","K00752//hyaluronan synthase [EC:2.4.1.212]","NP_619515.1//hyaluronan synthase 3 isoform b [Homo sapiens];XP_012597862.1//hyaluronan synthase 3 isoform X3 [Microcebus murinus];NP_005320.2//hyaluronan synthase 3 isoform a [Homo sapiens]","1//3;2//1"]
[4314,1906,0.08,0.13,0.700439718141092,0.781865098436719,"*",0.685686,"MMP3","GO:0031012//extracellular matrix;GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix","GO:0004252//serine-type endopeptidase activity;GO:0004175//endopeptidase activity;GO:0008237//metallopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding","GO:0032461//positive regulation of protein oligomerization;GO:0022617//extracellular matrix disassembly;GO:0071732//cellular response to nitric oxide;GO:0006508//proteolysis;GO:1903209//positive regulation of oxidative stress-induced cell death;GO:0010727//negative regulation of hydrogen peroxide metabolic process;GO:0030574//collagen catabolic process","K01394//matrix metalloproteinase-3 (stromelysin 1, progelatinase) [EC:3.4.24.17]","NP_002413.1//stromelysin-1 preproprotein [Homo sapiens]",4]
[84898,12135,0.16,0.26,0.700439718141092,0.128381482647585,"*",0.0628968,"PLXDC2","GO:0070062//extracellular exosome;GO:0016021//integral component of membrane","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K11447//histone demethylase [EC:1.14.11.-];K01064//wingless-type MMTV integration site family, member 9","NP_001269665.1//plexin domain-containing protein 2 isoform 2 [Homo sapiens];NP_116201.7//plexin domain-containing protein 2 isoform 1 precursor [Homo sapiens]","8;1//3"]
[5787,11707,0.08,0.13,0.700439718141092,0.423727686595583,"*",0.27863,"PTPRB","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane;GO:0070821//tertiary granule membrane;GO:0005886//plasma membrane;GO:0043235//receptor complex","GO:0005001//transmembrane receptor protein tyrosine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity","GO:0001525//angiogenesis;GO:0006470//protein dephosphorylation;GO:0043312//neutrophil degranulation;GO:0016311//dephosphorylation;GO:0006796//phosphate-containing compound metabolic process","K05694//receptor-type tyrosine-protein phosphatase beta [EC:3.1.3.48]","NP_001193900.1//receptor-type tyrosine-protein phosphatase beta isoform c precursor [Homo sapiens];NP_002828.3//receptor-type tyrosine-protein phosphatase beta isoform b precursor [Homo sapiens];NP_001103224.1//receptor-type tyrosine-protein phosphatase beta isoform a [Homo sapiens];NP_001317133.1//receptor-type tyrosine-protein phosphatase beta isoform e [Homo sapiens];NP_001193901.1//receptor-type tyrosine-protein phosphatase beta isoform d precursor [Homo sapiens]","1//3;3//A2MP1;2//1;5"]
[90249,3749,0.08,0.13,0.700439718141092,0.665710391400473,"*",0.546646,"UNC5A","GO:0031226//intrinsic component of plasma membrane;GO:0045121//membrane raft;GO:0016021//integral component of membrane;GO:0032809//neuronal cell body membrane;GO:0005886//plasma membrane;GO:0032589//neuron projection membrane","NA","GO:0033564//anterior/posterior axon guidance;GO:0031175//neuron projection development;GO:0038007//netrin-activated signaling pathway;GO:0007411//axon guidance;GO:0006915//apoptotic process","K07521//netrin receptor unc-5","EDL41165.1//unc-5 homolog A (C. elegans), isoform CRA_b, partial [Mus musculus]","2//1"]
[132228,1583,2.45,3.98,0.699986681541078,0.0194671524928846,"*",0.00727916,"LSMEM2","NA","NA","NA","K09291//nucleoprotein TPR","XP_011794412.1//PREDICTED: leucine-rich single-pass membrane protein 2 isoform X2 [Colobus angolensis palliatus];XP_011794411.1//PREDICTED: leucine-rich single-pass membrane protein 2 isoform X1 [Colobus angolensis palliatus]","1//3;2//1"]
[3754,2304,8.96,14.55,0.699448515738042,{"v":3.71106502189781e-09,"d":"3.71E-09"},"*",{"v":4.45588e-10,"d":"4.46E-10"},"KCNF1","NA","NA","NA","K04899//potassium voltage-gated channel subfamily F member 1","XP_017708824.1//PREDICTED: potassium voltage-gated channel subfamily F member 1 [Rhinopithecus bieti]",4]
[140731,3412,0.82,1.33,0.697730430883106,0.0506701034696589,"*",0.0214842,"ANKRD60","NA","NA","NA","K10380//ankyrin;K01064//wingless-type MMTV integration site family, member 9","NP_001291298.1//ankyrin repeat domain-containing protein 60 [Homo sapiens]","1//3"]
[3563,1479,0.71,1.15,0.695742931439693,0.47202310076378,"*",0.321114,"IL3RA","GO:0005622//intracellular;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004713//protein tyrosine kinase activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0004912//interleukin-3 receptor activity","GO:0000165//MAPK cascade","K04737//interleukin 3 receptor alpha","BAA08393.1//interleukin 3 receptor alpha subunit, partial [Homo sapiens];NP_001254642.1//interleukin-3 receptor subunit alpha isoform 2 precursor [Homo sapiens]","1//3;3//A2MP1"]
[56063,1154,2.98,4.82,0.6937208157678,0.0322765147839749,"*",0.0128609,"TMEM234","GO:0016021//integral component of membrane","NA","NA","K03246//translation initiation factor 3 subunit I;K15683//NF-X1-type zinc finger protein NFXL1","NP_061991.3//transmembrane protein 234 precursor [Homo sapiens]",4]
[27294,1098,0.6,0.97,0.693022246578609,0.430011970448949,"*",0.284216,"DHDH","NA","GO:0009055//electron transfer activity;GO:0047115//trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity;GO:0047837//D-xylose 1-dehydrogenase (NADP+) activity;GO:0008746//NAD(P)+ transhydrogenase activity;GO:0016491//oxidoreductase activity","GO:0005975//carbohydrate metabolic process;GO:0042843//D-xylose catabolic process","K00078//dihydrodiol dehydrogenase / D-xylose 1-dehydrogenase (NADP) [EC:1.3.1.20 1.1.1.179]","XP_004061157.2//PREDICTED: trans-1,2-dihydrobenzene-1,2-diol dehydrogenase [Gorilla gorilla gorilla]","3//A2MP1"]
[8609,8375,4.4,7.11,0.692346036094756,{"v":1.48713817677419e-13,"d":"1.49E-13"},"*",{"v":1.154408E-14,"d":"1.15E-14"},"KLF7","GO:0005634//nucleus","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003713//transcription coactivator activity;GO:0008270//zinc ion binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007411//axon guidance;GO:0048813//dendrite morphogenesis","K09228//KRAB domain-containing zinc finger protein;K09207//krueppel-like factor 6/7","XP_003363357.2//PREDICTED: Krueppel-like factor 7 [Equus caballus];NP_001257871.1//Krueppel-like factor 7 isoform 2 [Homo sapiens];XP_011510376.1//PREDICTED: Krueppel-like factor 7 isoform X5 [Homo sapiens];XP_008972505.1//PREDICTED: Krueppel-like factor 7 isoform X3 [Pan paniscus]","1//3;3//A2MP1"]
[91543,3512,0.13,0.21,0.691877704637668,0.447513668658946,"*",0.299986,"RSAD2","GO:0005783//endoplasmic reticulum;GO:0005741//mitochondrial outer membrane;GO:0005794//Golgi apparatus;GO:0005811//lipid droplet;GO:0001650//fibrillar center;GO:0005743//mitochondrial inner membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005739//mitochondrion","GO:0046872//metal ion binding;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0043621//protein self-association;GO:0003824//catalytic activity;GO:0051536//iron-sulfur cluster binding","GO:0060337//type I interferon signaling pathway;GO:0050709//negative regulation of protein secretion;GO:2000553//positive regulation of T-helper 2 cell cytokine production;GO:0051607//defense response to virus;GO:0016032//viral process;GO:0034157//positive regulation of toll-like receptor 7 signaling pathway;GO:0043367//CD4-positive, alpha-beta T cell differentiation;GO:0034165//positive regulation of toll-like receptor 9 signaling pathway;GO:0045071//negative regulation of viral genome replication;GO:0035710//CD4-positive, alpha-beta T cell activation;GO:0009615//response to virus","K15045//radical S-adenosyl methionine domain-containing protein 2","NP_542388.2//radical S-adenosyl methionine domain-containing protein 2 [Homo sapiens]",4]
[80008,1961,14.46,23.35,0.691354997645906,{"v":5.15351396735273e-12,"d":"5.15E-12"},"*",{"v":4.5457E-13,"d":"4.55E-13"},"TMEM156","GO:0016021//integral component of membrane","NA","NA","K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K01064//wingless-type MMTV integration site family, member 9;K12025//tripartite motif-containing protein 52","NP_079219.1//transmembrane protein 156 isoform 1 [Homo sapiens];NP_001290157.1//transmembrane protein 156 isoform 2 [Homo sapiens]","1//3;2//1"]
[4234,1294,22.17,35.78,0.690544617184601,{"v":3.8199242519685e-11,"d":"3.82E-11"},"*",{"v":3.6444e-12,"d":"3.64E-12"},"METTL1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol","GO:0000049//tRNA binding;GO:0008176//tRNA (guanine-N7-)-methyltransferase activity","NA","K03439//tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]","EAW97066.1//hCG2044065 [Homo sapiens];EAW97070.1//hCG2014568, isoform CRA_c [Homo sapiens]","3//A2MP1;5"]
[26229,1714,38.08,61.39,0.688970191194394,{"v":8.92623721276596e-25,"d":"8.93E-25"},"*",{"v":3.15162e-26,"d":"3.15E-26"},"B3GAT3","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005801//cis-Golgi network;GO:0000139//Golgi membrane","GO:0046872//metal ion binding;GO:0015018//galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity;GO:0015020//glucuronosyltransferase activity;GO:0072542//protein phosphatase activator activity","GO:0006486//protein glycosylation;GO:0090316//positive regulation of intracellular protein transport;GO:0006024//glycosaminoglycan biosynthetic process;GO:0005975//carbohydrate metabolic process;GO:0050650//chondroitin sulfate proteoglycan biosynthetic process;GO:0015012//heparan sulfate proteoglycan biosynthetic process;GO:0050651//dermatan sulfate proteoglycan biosynthetic process;GO:0030204//chondroitin sulfate metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0043085//positive regulation of catalytic activity","K10158//galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 [EC:2.4.1.135]","NP_036332.2//galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 isoform 1 [Homo sapiens];NP_001275651.1//galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 isoform 3 [Homo sapiens];XP_007993671.1//PREDICTED: galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 isoform X3 [Chlorocebus sabaeus];XP_016801977.1//PREDICTED: galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 isoform X1 [Pan troglodytes]","1//3;3//A2MP1"]
[8613,3324,7.32,11.79,0.68764816469572,{"v":2.4710284028777e-10,"d":"2.47E-10"},"*",{"v":2.58024E-11,"d":"2.58E-11"},"PLPP3","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005887//integral component of plasma membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005912//adherens junction","GO:0042577//lipid phosphatase activity;GO:0005178//integrin binding;GO:0004721//phosphoprotein phosphatase activity;GO:0042392//sphingosine-1-phosphate phosphatase activity;GO:0008195//phosphatidate phosphatase activity","GO:1902068//regulation of sphingolipid mediated signaling pathway;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0001568//blood vessel development;GO:0008354//germ cell migration;GO:0098609//cell-cell adhesion;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0046839//phospholipid dephosphorylation;GO:0044329//canonical Wnt signaling pathway involved in positive regulation of cell-cell adhesion;GO:0060020//Bergmann glial cell differentiation;GO:0034109//homotypic cell-cell adhesion;GO:0044328//canonical Wnt signaling pathway involved in positive regulation of endothelial cell migration;GO:0001702//gastrulation with mouth forming second;GO:0030148//sphingolipid biosynthetic process;GO:0030111//regulation of Wnt signaling pathway;GO:0060070//canonical Wnt signaling pathway;GO:0001933//negative regulation of protein phosphorylation;GO:0044330//canonical Wnt signaling pathway involved in positive regulation of wound healing;GO:0006644//phospholipid metabolic process;GO:0050821//protein stabilization;GO:0006629//lipid metabolic process","K01080//phosphatidate phosphatase [EC:3.1.3.4]","NP_003704.3//phospholipid phosphatase 3 [Homo sapiens]",4]
[3142,2308,3.92,6.31,0.686786350867341,0.0002139300099106,"*",{"v":5.24312E-5,"d":"5.24E-05"},"HLX","GO:0005634//nucleus","GO:0043565//sequence-specific DNA binding","GO:0001889//liver development;GO:0030154//cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0045627//positive regulation of T-helper 1 cell differentiation;GO:0006351//transcription, DNA-templated;GO:0045629//negative regulation of T-helper 2 cell differentiation;GO:0048484//enteric nervous system development;GO:0046622//positive regulation of organ growth;GO:0007275//multicellular organism development;GO:0007519//skeletal muscle tissue development;GO:0048557//embryonic digestive tract morphogenesis;GO:0008284//positive regulation of cell proliferation","K09339//homeobox protein HLX1","NP_068777.1//H2.0-like homeobox protein [Homo sapiens]","3//A2MP1"]
[10693,1773,0.23,0.37,0.685891409571937,0.578636030571061,"*",0.421824,"CCT6B","GO:0005829//cytosol;GO:0005832//chaperonin-containing T-complex","GO:0005524//ATP binding;GO:0051082//unfolded protein binding;GO:0008565//protein transporter activity;GO:0044183//protein binding involved in protein folding","GO:0006457//protein folding;GO:0051131//chaperone-mediated protein complex assembly;GO:0006458//'de novo' protein folding;GO:1901998//toxin transport;GO:0007283//spermatogenesis;GO:0061077//chaperone-mediated protein folding","K09498//T-complex protein 1 subunit zeta","NP_001180458.1//T-complex protein 1 subunit zeta-2 isoform 2 [Homo sapiens];NP_001180459.1//T-complex protein 1 subunit zeta-2 isoform 3 [Homo sapiens];NP_006575.2//T-complex protein 1 subunit zeta-2 isoform 1 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[140606,741,29.43,47.3,0.684552641286363,{"v":7.6983624774323e-09,"d":"7.70E-09"},"*",{"v":9.6097e-10,"d":"9.61E-10"},"SELENOM","GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0048471//perinuclear region of cytoplasm","NA","GO:0042445//hormone metabolic process;GO:0035934//corticosterone secretion;GO:0010269//response to selenium ion;GO:0060612//adipose tissue development;GO:0035264//multicellular organism growth","NA","NP_536355.1//selenoprotein M precursor [Homo sapiens]","3//A2MP1"]
[55601,6099,0.28,0.45,0.68449817427207,0.204228158701996,"*",0.1095294,"DDX60","GO:0045111//intermediate filament cytoskeleton;GO:0005829//cytosol","GO:0005524//ATP binding;GO:0003725//double-stranded RNA binding;GO:0003690//double-stranded DNA binding;GO:0003727//single-stranded RNA binding","GO:1900245//positive regulation of MDA-5 signaling pathway;GO:1900246//positive regulation of RIG-I signaling pathway;GO:0051607//defense response to virus","K20103//ATP-dependent RNA helicase DDX60 [EC:3.6.4.13]","XP_003899396.1//probable ATP-dependent RNA helicase DDX60 isoform X2 [Papio anubis]",5]
[22798,2652,0.89,1.43,0.684137905811992,0.0850588049491339,"*",0.0387328,"LAMB4","GO:0005604//basement membrane","NA","GO:0007155//cell adhesion","K06245//laminin, beta 4","NP_001304976.1//laminin subunit beta-4 isoform 2 precursor [Homo sapiens];NP_001304977.1//laminin subunit beta-4 isoform 3 precursor [Homo sapiens];XP_008961826.1//PREDICTED: LOW QUALITY PROTEIN: laminin subunit beta-4 [Pan paniscus]","1//3;2//1"]
[8701,13896,0.66,1.06,0.683526335204746,0.000166874665278501,"*",{"v":4.0136e-05,"d":"4.01E-05"},"DNAH11","GO:0005874//microtubule;GO:0030286//dynein complex;GO:0031514//motile cilium;GO:0005737//cytoplasm;GO:0005930//axoneme","GO:0051959//dynein light intermediate chain binding;GO:0045505//dynein intermediate chain binding;GO:0005524//ATP binding;GO:0003777//microtubule motor activity;GO:0045503//dynein light chain binding;GO:0008569//ATP-dependent microtubule motor activity, minus-end-directed","GO:0003341//cilium movement;GO:0007018//microtubule-based movement;GO:0030317//flagellated sperm motility;GO:0007368//determination of left/right symmetry;GO:0007507//heart development;GO:0003356//regulation of cilium beat frequency","K10408//dynein heavy chain, axonemal","NP_001264044.1//dynein heavy chain 11, axonemal [Homo sapiens]","1//3"]
[146822,667,0.71,1.14,0.68314289466006,0.482459788953914,"*",0.330298,"CDRT15","GO:0016021//integral component of membrane","NA","NA","NA","AAI46860.1//CMT1A duplicated region transcript 15 [Homo sapiens];NP_001335710.1//CMT1A duplicated region transcript 15 protein isoform 2 [Homo sapiens]","1//3;2//1"]
[122509,708,5.42,8.7,0.682722549382219,0.0325425014559147,"*",0.01298522,"IFI27L1","GO:0016021//integral component of membrane","NA","NA","NA","EAW81553.1//family with sequence similarity 14, member B, isoform CRA_a, partial [Homo sapiens];XP_016876450.1//PREDICTED: interferon alpha-inducible protein 27-like protein 1 isoform X2 [Homo sapiens]","2//1"]
[6253,1669,5.33,8.55,0.681788887014084,0.0191598556311819,"*",0.00715466,"RTN2","GO:0030315//T-tubule;GO:0005783//endoplasmic reticulum;GO:0014802//terminal cisterna;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","NA","GO:0065002//intracellular protein transmembrane transport;GO:0046324//regulation of glucose import","K20722//reticulon-2","NP_005610.1//reticulon-2 isoform A [Homo sapiens];NP_996783.1//reticulon-2 isoform B [Homo sapiens]","4;2//1"]
[84261,1750,5.11,8.19,0.680540160703387,0.000288894722211155,"*",{"v":7.26306e-05,"d":"7.26E-05"},"FBXW9","GO:0005829//cytosol","GO:0004842//ubiquitin-protein transferase activity","GO:0043687//post-translational protein modification;GO:0000209//protein polyubiquitination","K10265//F-box and WD-40 domain protein 9","NP_115677.2//F-box/WD repeat-containing protein 9 [Homo sapiens]","2//1"]
[4489,468,9.06,14.51,0.679464564020509,0.023978447962178,"*",0.0092077,"MT1A","NA","NA","NA","K14739//metallothionein 1/2","XP_009194736.1//metallothionein-1E isoform X2 [Papio anubis]","2//1"]
[81844,4723,6.9,11.05,0.679378102613262,{"v":2.65835031496063e-13,"d":"2.66E-13"},"*",{"v":2.1135E-14,"d":"2.11E-14"},"TRIM56","GO:0005829//cytosol;GO:0005622//intracellular;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0008270//zinc ion binding;GO:0004842//ubiquitin-protein transferase activity","GO:0070534//protein K63-linked ubiquitination;GO:0034340//response to type I interferon;GO:0032479//regulation of type I interferon production;GO:0032608//interferon-beta production;GO:0051607//defense response to virus","K12026//tripartite motif-containing protein 56 [EC:2.3.2.27]","NP_112223.1//E3 ubiquitin-protein ligase TRIM56 [Homo sapiens]","2//1"]
[3691,5783,16.23,25.99,0.679293633924229,{"v":2.57622811715976E-36,"d":"2.58E-36"},"*",{"v":5.45114e-38,"d":"5.45E-38"},"ITGB4","GO:0008305//integrin complex;GO:0070062//extracellular exosome;GO:0031252//cell leading edge;GO:0005634//nucleus;GO:0009986//cell surface;GO:0030056//hemidesmosome;GO:0030054//cell junction;GO:0005886//plasma membrane;GO:0043235//receptor complex","GO:0001664//G-protein coupled receptor binding;GO:0004872//receptor activity","GO:0009611//response to wounding;GO:0043588//skin development;GO:0031581//hemidesmosome assembly;GO:0048565//digestive tract development;GO:0097186//amelogenesis;GO:0007160//cell-matrix adhesion;GO:0007155//cell adhesion;GO:0072001//renal system development;GO:0035878//nail development;GO:0048870//cell motility;GO:0030198//extracellular matrix organization;GO:0007229//integrin-mediated signaling pathway;GO:0006914//autophagy;GO:0048333//mesodermal cell differentiation","K06525//integrin beta 4","XP_006721931.1//PREDICTED: integrin beta-4 isoform X4 [Homo sapiens];XP_006721930.1//PREDICTED: integrin beta-4 isoform X3 [Homo sapiens];XP_006721933.1//PREDICTED: integrin beta-4 isoform X6 [Homo sapiens]","4;1//3;2//1"]
[9149,2510,20.47,32.76,0.678424254617598,{"v":3.2570829007371e-19,"d":"3.26E-19"},"*",{"v":1.659738e-20,"d":"1.66E-20"},"DYRK1B","NA","NA","NA","K08825//dual specificity tyrosine-phosphorylation-regulated kinase 1 [EC:2.7.12.1]","XP_018871474.1//PREDICTED: dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform X2 [Gorilla gorilla gorilla];XP_018871473.1//PREDICTED: dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform X1 [Gorilla gorilla gorilla];XP_512657.3//PREDICTED: dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform X1 [Pan troglodytes]","2//1"]
[81793,3501,0.7,1.12,0.678071905112638,0.121375486832556,"*",0.0586286,"TLR10","GO:0016020//membrane;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004888//transmembrane signaling receptor activity","GO:0050729//positive regulation of inflammatory response;GO:0002224//toll-like receptor signaling pathway;GO:0006954//inflammatory response;GO:0050707//regulation of cytokine secretion;GO:0006955//immune response;GO:0034166//toll-like receptor 10 signaling pathway;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0045087//innate immune response","K10171//toll-like receptor 10","NP_112218.2//toll-like receptor 10 isoform a [Homo sapiens]","1//3;3//A2MP1;2//1"]
[5199,1669,0.15,0.24,0.678071905112638,0.628851793012217,"*",0.505908,"CFP","GO:0031012//extracellular matrix;GO:1904724//tertiary granule lumen;GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0035580//specific granule lumen;GO:0005576//extracellular region","NA","GO:0030449//regulation of complement activation;GO:0006956//complement activation;GO:0043312//neutrophil degranulation;GO:0006955//immune response;GO:0036066//protein O-linked fucosylation;GO:0042742//defense response to bacterium;GO:0006957//complement activation, alternative pathway","K15412//complement factor properdin","NP_002612.1//properdin precursor [Homo sapiens]","1//3;2//1"]
[4094,6887,0.05,0.08,0.678071905112638,0.540251097826087,"*",0.385826,"MAF","GO:0005634//nucleus;GO:0000785//chromatin;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0070306//lens fiber cell differentiation;GO:0032330//regulation of chondrocyte differentiation;GO:0048839//inner ear development;GO:0006351//transcription, DNA-templated;GO:0001816//cytokine production;GO:0048468//cell development;GO:0006366//transcription from RNA polymerase II promoter","K09035//transcription factor Maf","XP_016878722.1//PREDICTED: transcription factor Maf isoform X1 [Homo sapiens];NP_005351.2//transcription factor Maf isoform a [Homo sapiens]","4;2//1"]
[84530,8494,0.1,0.16,0.678071905112638,0.309472689278917,"*",0.1832348,"SRRM4","GO:0005634//nucleus","GO:0003729//mRNA binding","GO:0043484//regulation of RNA splicing;GO:0007399//nervous system development;GO:0006397//mRNA processing;GO:0030154//cell differentiation;GO:0007605//sensory perception of sound;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0008380//RNA splicing","K13172//serine/arginine repetitive matrix protein 2","NP_919262.2//serine/arginine repetitive matrix protein 4 [Homo sapiens]","3//A2MP1"]
[57644,6602,0.05,0.08,0.678071905112638,0.540061735366281,"*",0.385826,"MYH7B","GO:0016459//myosin complex;GO:0097512//cardiac myofibril","GO:0051015//actin filament binding;GO:0005524//ATP binding;GO:0003774//motor activity","NA","K10352//myosin heavy chain","XP_022350077.1//myosin-7B [Enhydra lutris kenyoni]",4]
[57549,4029,0.1,0.16,0.678071905112638,0.57883485748647,"*",0.421824,"IGSF9","NA","NA","NA","K17341//hemicentin","AAH30141.1//Immunoglobulin superfamily, member 9 [Homo sapiens];EHH50426.1//hypothetical protein EGM_01256 [Macaca fascicularis]","1//3;3//A2MP1"]
[7294,2914,0.05,0.08,0.678071905112638,0.781195932101847,"*",0.685686,"TXK","GO:0005634//nucleus;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0005737//cytoplasm","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005524//ATP binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0001012//RNA polymerase II regulatory region DNA binding","GO:0038083//peptidyl-tyrosine autophosphorylation;GO:0042127//regulation of cell proliferation;GO:0060335//positive regulation of interferon-gamma-mediated signaling pathway;GO:0042246//tissue regeneration;GO:0010543//regulation of platelet activation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007229//integrin-mediated signaling pathway;GO:0045087//innate immune response;GO:0032729//positive regulation of interferon-gamma production;GO:0030154//cell differentiation;GO:0050852//T cell receptor signaling pathway;GO:0006468//protein phosphorylation;GO:0001816//cytokine production;GO:0002250//adaptive immune response;GO:0046777//protein autophosphorylation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007202//activation of phospholipase C activity","K08016//tyrosine-protein kinase TXK [EC:2.7.10.2]","NP_003319.2//tyrosine-protein kinase TXK [Homo sapiens]","2//1"]
[283849,2505,0.1,0.16,0.678071905112638,0.628753940091807,"*",0.505908,"EXOC3L1","GO:0030141//secretory granule;GO:0000145//exocyst;GO:0030133//transport vesicle","GO:0000149//SNARE binding","GO:0030072//peptide hormone secretion;GO:0051601//exocyst localization;GO:0006887//exocytosis","K19987//exocyst complex component 3-like protein","NP_848611.2//exocyst complex component 3-like protein [Homo sapiens]","3//A2MP1"]
[58472,1810,34.79,55.54,0.674854498198956,{"v":2.93792286666667e-24,"d":"2.94E-24"},"*",{"v":1.081444e-25,"d":"1.08E-25"},"SQOR","GO:0005743//mitochondrial inner membrane","GO:0070224//sulfide:quinone oxidoreductase activity;GO:0048038//quinone binding;GO:0016491//oxidoreductase activity","GO:0070221//sulfide oxidation, using sulfide:quinone oxidoreductase;GO:0070813//hydrogen sulfide metabolic process","K17218//sulfide:quinone oxidoreductase [EC:1.8.5.4]","NP_067022.1//sulfide:quinone oxidoreductase, mitochondrial [Homo sapiens]","1//3;3//A2MP1"]
[1316,4643,13.1,20.91,0.674626250164767,{"v":2.5732418130137e-24,"d":"2.57E-24"},"*",{"v":9.40762e-26,"d":"9.41E-26"},"KLF6","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0001650//fibrillar center","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003676//nucleic acid binding","GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0030183//B cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated","K09207//krueppel-like factor 6/7","NP_001153597.1//Krueppel-like factor 6 isoform C [Homo sapiens];NP_001153596.1//Krueppel-like factor 6 isoform B [Homo sapiens];AAC23699.1//DNA-binding protein CPBP, partial [Homo sapiens]","1//3;5"]
[339456,987,0.42,0.67,0.673771767679012,0.578437340200876,"*",0.421824,"TMEM52","GO:0016021//integral component of membrane","NA","NA","NA","NP_848640.1//transmembrane protein 52 precursor [Homo sapiens]","3//A2MP1"]
[929,1540,2.21,3.52,0.671529059245866,0.0340524289878543,"*",0.01369004,"CD14","GO:0070062//extracellular exosome;GO:0010008//endosome membrane;GO:0030667//secretory granule membrane;GO:0005615//extracellular space;GO:0031362//anchored component of external side of plasma membrane;GO:0046696//lipopolysaccharide receptor complex;GO:0045121//membrane raft;GO:0005794//Golgi apparatus;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0001530//lipopolysaccharide binding;GO:0071723//lipopeptide binding;GO:0001847//opsonin receptor activity;GO:0070891//lipoteichoic acid binding;GO:0016019//peptidoglycan receptor activity","GO:0032481//positive regulation of type I interferon production;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0097190//apoptotic signaling pathway;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0032026//response to magnesium ion;GO:0071222//cellular response to lipopolysaccharide;GO:0007166//cell surface receptor signaling pathway;GO:0045807//positive regulation of endocytosis;GO:0045471//response to ethanol;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0032760//positive regulation of tumor necrosis factor production;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0045087//innate immune response;GO:0032729//positive regulation of interferon-gamma production;GO:0006909//phagocytosis;GO:0009408//response to heat;GO:0006915//apoptotic process;GO:0071726//cellular response to diacyl bacterial lipopeptide;GO:0034612//response to tumor necrosis factor;GO:0006898//receptor-mediated endocytosis;GO:0051602//response to electrical stimulus;GO:0043312//neutrophil degranulation;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0034142//toll-like receptor 4 signaling pathway;GO:0071727//cellular response to triacyl bacterial lipopeptide;GO:0071223//cellular response to lipoteichoic acid;GO:0002224//toll-like receptor signaling pathway;GO:0034128//negative regulation of MyD88-independent toll-like receptor signaling pathway;GO:0006954//inflammatory response;GO:0071219//cellular response to molecule of bacterial origin;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:2000484//positive regulation of interleukin-8 secretion;GO:0070266//necroptotic process;GO:0002755//MyD88-dependent toll-like receptor signaling pathway","K04391//monocyte differentiation antigen CD14","NP_000582.1//monocyte differentiation antigen CD14 precursor [Homo sapiens]","1//3;3//A2MP1;2//1"]
[5720,1033,50.84,80.97,0.671423447183049,{"v":1.00692348392371E-20,"d":"1.01E-20"},"*",{"v":4.62678e-22,"d":"4.63E-22"},"PSME1","NA","NA","NA","K06696//proteasome activator subunit 1 (PA28 alpha)","XP_509864.3//PREDICTED: proteasome activator complex subunit 1 isoform X2 [Pan troglodytes];XP_009425837.1//PREDICTED: proteasome activator complex subunit 1 isoform X1 [Pan troglodytes]","1//3;3//A2MP1;2//1"]
[286183,1854,0.22,0.35,0.669851398307669,0.578785137948806,"*",0.421824,"NKAIN3","GO:0016021//integral component of membrane","NA","NA","NA","NP_001291462.1//sodium/potassium-transporting ATPase subunit beta-1-interacting protein 3 precursor [Homo sapiens]","1//3"]
[10417,1825,0.22,0.35,0.669851398307669,0.578536668326608,"*",0.421824,"SPON2","GO:0070062//extracellular exosome;GO:0005578//proteinaceous extracellular matrix","GO:0046872//metal ion binding;GO:0001530//lipopolysaccharide binding;GO:0003823//antigen binding","GO:0050832//defense response to fungus;GO:0032755//positive regulation of interleukin-6 production;GO:0051607//defense response to virus;GO:0071222//cellular response to lipopolysaccharide;GO:0002448//mast cell mediated immunity;GO:0032760//positive regulation of tumor necrosis factor production;GO:0007155//cell adhesion;GO:0060907//positive regulation of macrophage cytokine production;GO:0043152//induction of bacterial agglutination;GO:0007411//axon guidance;GO:0045087//innate immune response;GO:0008228//opsonization","K22020//mucin-19;K06532//prominin 1","XP_004091742.1//PREDICTED: LOW QUALITY PROTEIN: spondin-2 [Nomascus leucogenys]","1//3;3//A2MP1;2//1"]
[4008,7018,4.74,7.54,0.669677464370405,{"v":1.16341351875E-12,"d":"1.16E-12"},"*",{"v":9.78858e-14,"d":"9.79E-14"},"LMO7","GO:0005634//nucleus;GO:0005925//focal adhesion;GO:0000151//ubiquitin ligase complex;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0004842//ubiquitin-protein transferase activity","GO:0043687//post-translational protein modification;GO:0016567//protein ubiquitination;GO:0030155//regulation of cell adhesion;GO:0023051//regulation of signaling;GO:0000209//protein polyubiquitination","K06084//F-box protein 20","XP_016780876.1//PREDICTED: LIM domain only protein 7 isoform X11 [Pan troglodytes];NP_005349.3//LIM domain only protein 7 isoform 1 [Homo sapiens];Q8WWI1.3//RecName: Full=LIM domain only protein 7; Short=LMO-7; AltName: Full=F-box only protein 20; AltName: Full=LOMP;ACV60543.1//LIM domain only 7 protein [Homo sapiens]","1//3;2//1;5"]
[54704,4254,2.51,3.99,0.668701382271574,0.000110152460367171,"*",{"v":2.55418E-5,"d":"2.55E-05"},"PDP1","NA","NA","NA","K01102//pyruvate dehydrogenase phosphatase [EC:3.1.3.43]","AAH64978.1//PPM2C protein, partial [Homo sapiens];XP_003311895.1//PREDICTED: pyruvate dehyrogenase phosphatase catalytic subunit 1 isoform X2 [Pan troglodytes];XP_019780696.1//PREDICTED: pyruvate dehyrogenase phosphatase catalytic subunit 1 isoform X1 [Tursiops truncatus];XP_016869077.1//PREDICTED: pyruvate dehyrogenase phosphatase catalytic subunit 1 isoform X2 [Homo sapiens]","1//3;3//A2MP1"]
[56246,673,1.9,3.02,0.668549130994131,0.213878768373598,"*",0.1158298,"MRAP","GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane","GO:0031783//type 5 melanocortin receptor binding;GO:0031780//corticotropin hormone receptor binding;GO:0031782//type 4 melanocortin receptor binding;GO:0042802//identical protein binding;GO:0070996//type 1 melanocortin receptor binding;GO:0031781//type 3 melanocortin receptor binding","GO:0050873//brown fat cell differentiation;GO:0030819//positive regulation of cAMP biosynthetic process;GO:0034394//protein localization to cell surface","NA","EAX09880.1//melanocortin 2 receptor accessory protein, isoform CRA_c, partial [Homo sapiens];NP_848932.1//melanocortin-2 receptor accessory protein isoform alpha [Homo sapiens];NP_996781.1//melanocortin-2 receptor accessory protein isoform beta [Homo sapiens]","1//3;3//A2MP1"]
[3566,3627,9.86,15.65,0.666503105442069,{"v":2.67868018568057e-13,"d":"2.68E-13"},"*",{"v":2.13134E-14,"d":"2.13E-14"},"IL4R","NA","NA","NA","K05071//interleukin 4 receptor","XP_009428807.2//PREDICTED: interleukin-4 receptor subunit alpha isoform X1 [Pan troglodytes];XP_510892.4//PREDICTED: interleukin-4 receptor subunit alpha isoform X2 [Pan troglodytes];XP_011544130.1//PREDICTED: interleukin-4 receptor subunit alpha isoform X2 [Homo sapiens]","1//3;3//A2MP1"]
[432,1402,0.29,0.46,0.665580960929441,0.578586345182895,"*",0.421824,"ASGR1","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0004873//asialoglycoprotein receptor activity;GO:0046872//metal ion binding;GO:0030246//carbohydrate binding;GO:0042803//protein homodimerization activity","GO:0018279//protein N-linked glycosylation via asparagine;GO:0006898//receptor-mediated endocytosis;GO:0006897//endocytosis;GO:0031668//cellular response to extracellular stimulus","K10063//asialoglycoprotein receptor 1","NP_001184145.1//asialoglycoprotein receptor 1 isoform b [Homo sapiens];NP_001662.1//asialoglycoprotein receptor 1 isoform a [Homo sapiens]","4;2//1"]
[4335,4865,13.01,20.63,0.665122859168689,{"v":8.34858365562914e-24,"d":"8.35E-24"},"*",{"v":3.15672e-25,"d":"3.16E-25"},"MNT","GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0003714//transcription corepressor activity;GO:0003713//transcription coactivator activity;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0003700//DNA binding transcription factor activity;GO:0001227//transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0046983//protein dimerization activity","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007275//multicellular organism development;GO:0007569//cell aging;GO:0051726//regulation of cell cycle;GO:0006366//transcription from RNA polymerase II promoter;GO:0008285//negative regulation of cell proliferation;GO:2001234//negative regulation of apoptotic signaling pathway","K09115//MAX-binding protein","NP_064706.1//max-binding protein MNT [Homo sapiens]","2//1"]
[79929,2154,1.64,2.6,0.664815808410371,0.0358803576274328,"*",0.01454172,"MAP6D1","GO:0005874//microtubule;GO:0005798//Golgi-associated vesicle;GO:0005801//cis-Golgi network","GO:0005516//calmodulin binding;GO:0008017//microtubule binding","GO:0000226//microtubule cytoskeleton organization;GO:0018009//N-terminal peptidyl-L-cysteine N-palmitoylation;GO:0007026//negative regulation of microtubule depolymerization;GO:0032418//lysosome localization;GO:0048813//dendrite morphogenesis","K10432//microtubule-associated protein 6;K09650//rhomboid-like protein [EC:3.4.21.105]","NP_079147.1//MAP6 domain-containing protein 1 [Homo sapiens]","2//1"]
[23464,1606,2.17,3.44,0.664713522257619,0.0417410064781491,"*",0.01728016,"GCAT","GO:0005654//nucleoplasm;GO:0016607//nuclear speck;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0030170//pyridoxal phosphate binding;GO:0008890//glycine C-acetyltransferase activity;GO:0016874//ligase activity","GO:0009058//biosynthetic process;GO:0006520//cellular amino acid metabolic process;GO:0006567//threonine catabolic process;GO:0019518//L-threonine catabolic process to glycine","K00639//glycine C-acetyltransferase [EC:2.3.1.29]","NP_001165161.1//2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial isoform 1 precursor [Homo sapiens];NP_055106.1//2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial isoform 2 precursor [Homo sapiens]","1//3;3//A2MP1"]
[1827,2131,2.57,4.07,0.663260435072369,0.0219307391255568,"*",0.00832116,"RCAN1","GO:0005634//nucleus;GO:0005622//intracellular;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0042802//identical protein binding;GO:0008597//calcium-dependent protein serine/threonine phosphatase regulator activity;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0009612//response to mechanical stimulus;GO:0007165//signal transduction;GO:0051151//negative regulation of smooth muscle cell differentiation;GO:0043627//response to estrogen;GO:0007417//central nervous system development;GO:0008015//blood circulation;GO:0033173//calcineurin-NFAT signaling cascade;GO:0007519//skeletal muscle tissue development;GO:0070884//regulation of calcineurin-NFAT signaling cascade","K17901//calcipressin-1","NP_001272318.1//calcipressin-1 isoform d [Homo sapiens];XP_020018408.1//calcipressin-1 isoform X1 [Castor canadensis];NP_001272320.2//calcipressin-1 isoform e [Homo sapiens];EHH16988.1//Regulator of calcineurin 1, partial [Macaca mulatta];NP_004405.3//calcipressin-1 isoform a [Homo sapiens];NP_981963.1//calcipressin-1 isoform c [Homo sapiens];XP_003263947.1//PREDICTED: calcipressin-1 isoform X3 [Nomascus leucogenys];NP_001317945.1//calcipressin-1 isoform f [Homo sapiens]","6;1//3;2//1"]
[51555,8635,0.12,0.19,0.662965012722429,0.366817782178218,"*",0.227292,"PEX5L","GO:0005829//cytosol;GO:0043235//receptor complex;GO:0005778//peroxisomal membrane","GO:0031267//small GTPase binding;GO:0005052//peroxisome matrix targeting signal-1 binding;GO:0000268//peroxisome targeting sequence binding","GO:0043949//regulation of cAMP-mediated signaling;GO:0016560//protein import into peroxisome matrix, docking","K13342//peroxin-5","XP_018879929.1//PREDICTED: PEX5-related protein isoform X7 [Gorilla gorilla gorilla];NP_001243681.1//PEX5-related protein isoform 4 [Homo sapiens];NP_001336327.1//PEX5-related protein isoform 18 [Homo sapiens];NP_001243679.1//PEX5-related protein isoform 2 [Homo sapiens];XP_021790337.1//PEX5-related protein isoform X15 [Papio anubis];NP_001336325.1//PEX5-related protein isoform 16 [Homo sapiens];NP_001336319.1//PEX5-related protein isoform 12 [Homo sapiens];NP_001336322.1//PEX5-related protein isoform 14 [Homo sapiens];NP_001243682.1//PEX5-related protein isoform 5 [Homo sapiens];NP_001336318.1//PEX5-related protein isoform 11 [Homo sapiens];NP_001336315.1//PEX5-related protein isoform 9 [Homo sapiens];XP_018879928.1//PREDICTED: PEX5-related protein isoform X1 [Gorilla gorilla gorilla];NP_001336320.1//PEX5-related protein isoform 13 [Homo sapiens];BAH12041.1//unnamed protein product [Homo sapiens];NP_001336326.1//PEX5-related protein isoform 17 [Homo sapiens];NP_057643.1//PEX5-related protein isoform 1 [Homo sapiens];NP_001243680.1//PEX5-related protein isoform 3 [Homo sapiens]","1//3;2//1"]
[89765,1331,0.12,0.19,0.662965012722429,0.781641915649754,"*",0.685686,"RSPH1","GO:0005634//nucleus;GO:0072687//meiotic spindle;GO:0031514//motile cilium;GO:0005829//cytosol;GO:0000794//condensed nuclear chromosome;GO:0001520//outer dense fiber","NA","GO:0051321//meiotic cell cycle;GO:0035082//axoneme assembly;GO:0007286//spermatid development","K19755//radial spoke head protein 1","NP_543136.1//radial spoke head 1 homolog isoform 1 [Homo sapiens];NP_001273435.1//radial spoke head 1 homolog isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[55040,3944,0.24,0.38,0.662965012722429,0.350501208929123,"*",0.213298,"EPN3","GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0030136//clathrin-coated vesicle;GO:0048471//perinuclear region of cytoplasm;GO:0019897//extrinsic component of plasma membrane;GO:0005905//clathrin-coated pit","GO:0008289//lipid binding;GO:1990175//EH domain binding","NA","K12471//epsin","NP_060427.2//epsin-3 [Homo sapiens]","2//1"]
[206412,1304,0.12,0.19,0.662965012722429,0.781140219940094,"*",0.685686,"C6orf163","NA","NA","NA","K18730//PERQ amino acid-rich with GYF domain-containing protein;K20283//golgin subfamily A member 4","NP_001010868.2//uncharacterized protein C6orf163 [Homo sapiens]","2//1"]
[2170,1309,0.12,0.19,0.662965012722429,0.780416684289277,"*",0.685686,"FABP3","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0016528//sarcoplasm;GO:0005829//cytosol","GO:0008289//lipid binding;GO:0036041//long-chain fatty acid binding;GO:0008092//cytoskeletal protein binding;GO:0070538//oleic acid binding;GO:0005324//long-chain fatty acid transporter activity;GO:0005215//transporter activity;GO:0050543//icosatetraenoic acid binding","GO:0019433//triglyceride catabolic process;GO:2001245//regulation of phosphatidylcholine biosynthetic process;GO:0055091//phospholipid homeostasis;GO:0042493//response to drug;GO:0032868//response to insulin;GO:0071073//positive regulation of phospholipid biosynthetic process;GO:0046320//regulation of fatty acid oxidation;GO:0006631//fatty acid metabolic process;GO:0042632//cholesterol homeostasis;GO:0070542//response to fatty acid;GO:0044539//long-chain fatty acid import;GO:0008285//negative regulation of cell proliferation","K08752//fatty acid-binding protein 3, muscle and heart","NP_001307925.1//fatty acid-binding protein, heart isoform 1 [Homo sapiens];NP_004093.1//fatty acid-binding protein, heart isoform 2 [Homo sapiens]","1//3;4"]
[79095,723,59.15,93.64,0.662746765884862,{"v":2.20867665901943e-15,"d":"2.21E-15"},"*",{"v":1.494666e-16,"d":"1.49E-16"},"C9orf16","NA","NA","NA","K07603//collagen, type XVII, alpha;K14283//transforming acidic coiled-coil-containing protein 3","BAE01657.1//unnamed protein product [Macaca fascicularis]","3//A2MP1"]
[57168,3313,0.67,1.06,0.661831264105427,0.122530341429311,"*",0.0592478,"ASPHD2","NA","NA","NA","K00476//aspartate beta-hydroxylase [EC:1.14.11.16]","XP_021777112.1//aspartate beta-hydroxylase domain-containing protein 2 [Papio anubis]",4]
[89887,3867,6.48,10.25,0.661558191508184,{"v":7.62464668394366e-10,"d":"7.62E-10"},"*",{"v":8.47236e-11,"d":"8.47E-11"},"ZNF628","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","NP_149104.3//zinc finger protein 628 [Homo sapiens]","2//1"]
[90416,1723,4.52,7.14,0.659601301613912,0.00121608312098548,"*",3.46082E-4,"CCDC32","NA","NA","NA","K10392//kinesin family member 1;K17423//large subunit ribosomal protein L42","XP_008568451.1//PREDICTED: uncharacterized protein C15orf57 homolog isoform X3 [Galeopterus variegatus];NP_001074260.1//uncharacterized protein C15orf57 isoform 1 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[80176,3130,17.57,27.75,0.659373580116455,{"v":2.1675973539281e-20,"d":"2.17E-20"},"*",{"v":1.019072E-21,"d":"1.02E-21"},"SPSB1","NA","NA","NA","K10343//SPRY domain-containing SOCS box protein 1/4","BAD92796.1//SPRY domain-containing SOCS box protein SSB-1 variant, partial [Homo sapiens]","3//A2MP1"]
[400745,3753,4.54,7.17,0.65928082141099,{"v":1.49328406472968e-06,"d":"1.49E-06"},"*",{"v":2.54178e-07,"d":"2.54E-07"},"SH2D5","GO:0030054//cell junction;GO:0014069//postsynaptic density;GO:0045211//postsynaptic membrane","NA","NA","K18080//tensin;K22020//mucin-19","XP_008965308.1//PREDICTED: SH2 domain-containing protein 5 isoform X1 [Pan paniscus];XP_011935704.1//PREDICTED: SH2 domain-containing protein 5 isoform X1 [Cercocebus atys]","1//3"]
[717,1955,0.83,1.31,0.658383570190526,0.139052636895642,"*",0.0693174,"C2","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005576//extracellular region","GO:0004252//serine-type endopeptidase activity;GO:0046872//metal ion binding","GO:0006958//complement activation, classical pathway;GO:0030449//regulation of complement activation;GO:0006956//complement activation;GO:2000427//positive regulation of apoptotic cell clearance;GO:0007584//response to nutrient;GO:0045087//innate immune response","K01332//complement component 2 [EC:3.4.21.43]","NP_000054.2//complement C2 isoform 1 preproprotein [Homo sapiens];NP_001139375.1//complement C2 isoform 2 precursor [Homo sapiens];NP_001269388.1//complement C2 isoform 6 precursor [Homo sapiens];NP_001269387.1//complement C2 isoform 5 [Homo sapiens];NP_001171534.1//complement C2 isoform 3 [Homo sapiens];NP_001269386.1//complement C2 isoform 4 [Homo sapiens]","1//3;2//1;5"]
[29107,1176,33.5,52.87,0.658288231148445,{"v":2.05340060086133e-14,"d":"2.05E-14"},"*",{"v":1.492424E-15,"d":"1.49E-15"},"NXT1","NA","NA","NA","K14285//NTF2-related export protein 1/2","XP_012388659.1//PREDICTED: NTF2-related export protein 1 isoform X1 [Orcinus orca]","2//1"]
[2788,4264,0.52,0.82,0.657112286476991,0.0939109754897987,"*",0.0435104,"GNG7","NA","NA","NA","K04543//guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7","BAB15755.1//FLJ00058 protein, partial [Homo sapiens]","2//1"]
[770,1870,10.28,16.21,0.657043826323664,{"v":1.44020875255973E-7,"d":"1.44E-07"},"*",{"v":2.11334E-8,"d":"2.11E-08"},"CA11","GO:0005576//extracellular region","NA","NA","K01672//carbonic anhydrase [EC:4.2.1.1];K18245//carbonic anhydrase 2 [EC:4.2.1.1]","XP_005879554.1//PREDICTED: carbonic anhydrase-related protein 11 isoform X2 [Myotis brandtii]",4]
[3931,1354,3.28,5.17,0.656468465696851,0.0178288865031298,"*",0.00659738,"LCAT","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0034364//high-density lipoprotein particle;GO:0005576//extracellular region","GO:0004607//phosphatidylcholine-sterol O-acyltransferase activity;GO:0034186//apolipoprotein A-I binding","GO:0046470//phosphatidylcholine metabolic process;GO:0008203//cholesterol metabolic process;GO:0034435//cholesterol esterification;GO:0090107//regulation of high-density lipoprotein particle assembly;GO:0030301//cholesterol transport;GO:0034372//very-low-density lipoprotein particle remodeling;GO:0034375//high-density lipoprotein particle remodeling;GO:0006644//phospholipid metabolic process;GO:0042632//cholesterol homeostasis;GO:0043691//reverse cholesterol transport;GO:0042158//lipoprotein biosynthetic process;GO:0006656//phosphatidylcholine biosynthetic process","K00650//lecithin-cholesterol acyltransferase [EC:2.3.1.43]","NP_000220.1//phosphatidylcholine-sterol acyltransferase precursor [Homo sapiens]","1//3"]
[24142,1274,8.51,13.4,0.655001963659172,0.000240601238326996,"*",{"v":5.94198e-05,"d":"5.94E-05"},"NAT6","GO:0005737//cytoplasm","GO:0008080//N-acetyltransferase activity","NA","K00463//indoleamine 2,3-dioxygenase [EC:1.13.11.52];K11647//SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:3.6.4.-];K01197//hyaluronoglucosaminidase [EC:3.2.1.35];K06831//galectin-3","NP_036323.2//N-acetyltransferase 6 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[486,584,10.69,16.83,0.654773323609458,0.00627367872606635,"*",2.07172E-3,"FXYD2","GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0016323//basolateral plasma membrane;GO:0005890//sodium:potassium-exchanging ATPase complex;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane","GO:0005391//sodium:potassium-exchanging ATPase activity;GO:0005216//ion channel activity;GO:0017080//sodium channel regulator activity;GO:0005215//transporter activity","GO:0006810//transport;GO:0001558//regulation of cell growth;GO:1903779//regulation of cardiac conduction;GO:0034220//ion transmembrane transport;GO:0036376//sodium ion export across plasma membrane;GO:0042127//regulation of cell proliferation;GO:0090662//ATP hydrolysis coupled transmembrane transport;GO:2000649//regulation of sodium ion transmembrane transporter activity;GO:1990573//potassium ion import across plasma membrane","K01538//sodium/potassium-transporting ATPase subunit gamma (FXYD domain-containing ion transport regulator 2)","CAA60152.1//gamma subunit of sodium potassium ATPase like [Homo sapiens]","4;3//A2MP1"]
[57862,2652,15.95,25.09,0.653556046756941,{"v":6.12207022608696e-16,"d":"6.12E-16"},"*",{"v":3.96666e-17,"d":"3.97E-17"},"ZNF410","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","NP_001229855.1//zinc finger protein 410 isoform c [Homo sapiens];NP_067011.1//zinc finger protein 410 isoform b [Homo sapiens];NP_001229853.1//zinc finger protein 410 isoform a [Homo sapiens];XP_012914270.1//PREDICTED: zinc finger protein 410 isoform X3 [Mustela putorius furo];NP_001229856.1//zinc finger protein 410 isoform d [Homo sapiens]","1//3;2//1"]
[54936,1701,11.24,17.68,0.653476239170506,{"v":1.93246569656329e-07,"d":"1.93E-07"},"*",{"v":2.88648E-8,"d":"2.89E-08"},"ADPRHL2","GO:0005759//mitochondrial matrix;GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0005739//mitochondrion","GO:0004649//poly(ADP-ribose) glycohydrolase activity;GO:0046872//metal ion binding","GO:0071451//cellular response to superoxide","K11687//poly(ADP-ribose) glycohydrolase ARH3 [EC:3.2.1.143]","XP_007977605.1//PREDICTED: poly(ADP-ribose) glycohydrolase ARH3 isoform X2 [Chlorocebus sabaeus]","2//1"]
[26471,884,3.04,4.78,0.652939294537163,0.104551837637984,"*",0.0492128,"NUPR1","GO:0005634//nucleus;GO:0005829//cytosol;GO:0032993//protein-DNA complex","GO:0003677//DNA binding;GO:0003682//chromatin binding","GO:2000194//regulation of female gonad development;GO:0045786//negative regulation of cell cycle;GO:0006351//transcription, DNA-templated;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0006473//protein acetylation;GO:0048147//negative regulation of fibroblast proliferation;GO:0016049//cell growth;GO:0002526//acute inflammatory response;GO:0009636//response to toxic substance;GO:0008584//male gonad development;GO:0035914//skeletal muscle cell differentiation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0043065//positive regulation of apoptotic process;GO:0031401//positive regulation of protein modification process;GO:0006461//protein complex assembly","K15626//nuclear protein, 1","NP_036517.1//nuclear protein 1 isoform b [Homo sapiens];NP_001035948.1//nuclear protein 1 isoform a [Homo sapiens]","1//3;2//1"]
[80776,1049,7.52,11.82,0.652425468499895,0.00148569607530837,"*",0.000429786,"B9D2","GO:0016020//membrane;GO:0036064//ciliary basal body;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005813//centrosome;GO:0036038//MKS complex","GO:0043015//gamma-tubulin binding","GO:0060271//cilium assembly;GO:0097711//ciliary basal body-plasma membrane docking;GO:0007062//sister chromatid cohesion","K16745//B9 domain-containing protein 2","XP_006771929.1//PREDICTED: B9 domain-containing protein 2 isoform X1 [Myotis davidii]","3//A2MP1"]
[151516,2216,0.14,0.22,0.652076696579693,0.666421674730978,"*",0.546646,"ASPRV1","NA","NA","NA","NA","XP_005575723.1//PREDICTED: retroviral-like aspartic protease 1 [Macaca fascicularis]","2//1"]
[8532,2397,0.07,0.11,0.652076696579693,0.782311846582387,"*",0.685686,"CPZ","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005578//proteinaceous extracellular matrix","GO:0004185//serine-type carboxypeptidase activity;GO:0008270//zinc ion binding;GO:0004181//metallocarboxypeptidase activity","GO:0006508//proteolysis;GO:0016485//protein processing;GO:0006518//peptide metabolic process;GO:0016055//Wnt signaling pathway","K13022//carboxypeptidase Z [EC:3.4.17.-]","NP_003643.2//carboxypeptidase Z isoform 2 precursor [Homo sapiens];NP_001014447.1//carboxypeptidase Z isoform 1 precursor [Homo sapiens]","3//A2MP1;2//1"]
[729359,6353,0.07,0.11,0.652076696579693,0.608819056225238,"*",0.452136,"PLIN4","GO:0043231//intracellular membrane-bounded organelle;GO:0005811//lipid droplet;GO:0005829//cytosol;GO:0005886//plasma membrane","NA","NA","K20254//perilipin-4","NP_001073869.1//perilipin-4 [Homo sapiens]","1//3"]
[4685,4176,0.07,0.11,0.652076696579693,0.629096558617468,"*",0.505908,"NCAM2","GO:0030424//axon;GO:0016604//nuclear body;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0042802//identical protein binding","GO:0007413//axonal fasciculation;GO:0007608//sensory perception of smell;GO:0007158//neuron cell-cell adhesion","K06491//neural cell adhesion molecule","XP_020926518.1//neural cell adhesion molecule 2 isoform X2 [Sus scrofa];NP_001339526.1//neural cell adhesion molecule 2 isoform 8 [Homo sapiens];XP_020926517.1//neural cell adhesion molecule 2 isoform X1 [Sus scrofa];NP_001339521.1//neural cell adhesion molecule 2 isoform 3 [Homo sapiens];NP_001339524.1//neural cell adhesion molecule 2 isoform 6 precursor [Homo sapiens]","4;1//3"]
[56103,4602,0.07,0.11,0.652076696579693,0.666167470552334,"*",0.546646,"PCDHGB2","NA","NA","NA","K16496//protocadherin gamma subfamily B","NP_001076031.1//protocadherin gamma-B2 precursor [Pan troglodytes]","1//3;2//1"]
[392490,2269,0.07,0.11,0.652076696579693,0.781474612157534,"*",0.685686,"FLJ44635","GO:0070062//extracellular exosome;GO:0005737//cytoplasm","GO:0005509//calcium ion binding;GO:0008017//microtubule binding","GO:0030154//cell differentiation","K01115//phospholipase D1/2 [EC:3.1.4.4]","NP_997305.2//TPT1-like protein [Homo sapiens]","2//1"]
[5798,3570,0.07,0.11,0.652076696579693,0.628558325581395,"*",0.505908,"PTPRN","GO:0030658//transport vesicle membrane;GO:0030424//axon;GO:0005634//nucleus;GO:0030054//cell junction;GO:0043204//perikaryon;GO:0043025//neuronal cell body;GO:0005768//endosome;GO:0030141//secretory granule;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0043679//axon terminus;GO:0045202//synapse;GO:0005886//plasma membrane","GO:0044389//ubiquitin-like protein ligase binding;GO:0051020//GTPase binding;GO:0008134//transcription factor binding;GO:0030507//spectrin binding","GO:1904692//positive regulation of type B pancreatic cell proliferation;GO:0032868//response to insulin;GO:0051591//response to cAMP;GO:0006351//transcription, DNA-templated;GO:0043627//response to estrogen;GO:0030073//insulin secretion;GO:0000302//response to reactive oxygen species;GO:0035773//insulin secretion involved in cellular response to glucose stimulus;GO:0001553//luteinization;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0019221//cytokine-mediated signaling pathway;GO:1990502//dense core granule maturation","K07817//receptor-type tyrosine-protein phosphatase N [EC:3.1.3.48]","NP_001186692.1//receptor-type tyrosine-protein phosphatase-like N isoform 2 precursor [Homo sapiens];NP_002837.1//receptor-type tyrosine-protein phosphatase-like N isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[170958,6153,0.07,0.11,0.652076696579693,0.578487,"*",0.421824,"ZNF525","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0035556//intracellular signal transduction","K09228//KRAB domain-containing zinc finger protein","XP_011766061.1//PREDICTED: zinc finger protein 761 isoform X2 [Macaca nemestrina];XP_016789852.1//PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 813-like [Pan troglodytes]","1//3"]
[3484,1608,4.92,7.73,0.651810098585608,0.00134528754789439,"*",0.000385968,"IGFBP1","GO:0005615//extracellular space;GO:0005794//Golgi apparatus;GO:0005576//extracellular region","GO:0005520//insulin-like growth factor binding;GO:0031994//insulin-like growth factor I binding;GO:0031995//insulin-like growth factor II binding","GO:0001558//regulation of cell growth","K10138//insulin-like growth factor-binding protein 3","XP_519083.3//PREDICTED: insulin-like growth factor-binding protein 1 [Pan troglodytes]","3//A2MP1"]
[64761,3824,4.76,7.47,0.650146669481294,{"v":3.48099813538711e-07,"d":"3.48E-07"},"*",{"v":5.376E-8,"d":"5.38E-08"},"PARP12","GO:0005634//nucleus","GO:0003723//RNA binding;GO:0046872//metal ion binding;GO:0003950//NAD+ ADP-ribosyltransferase activity","NA","K15259//poly [ADP-ribose] polymerase 7/11/12/13 [EC:2.4.2.30]","NP_073587.1//poly [ADP-ribose] polymerase 12 [Homo sapiens]","3//A2MP1"]
[1662,3289,13.34,20.93,0.649813645071124,{"v":6.52962281581485e-16,"d":"6.53E-16"},"*",{"v":4.2389e-17,"d":"4.24E-17"},"DDX10","GO:0005730//nucleolus;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0004004//ATP-dependent RNA helicase activity;GO:0005524//ATP binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity","GO:0010501//RNA secondary structure unwinding","K14776//ATP-dependent RNA helicase DDX10/DBP4 [EC:3.6.4.13]","XP_008951975.1//PREDICTED: probable ATP-dependent RNA helicase DDX10 [Pan paniscus]","3//A2MP1"]
[10865,2114,5.1,8,0.649502752915867,0.000315721365247525,"*",{"v":7.98494e-05,"d":"7.98E-05"},"ARID5A","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus","GO:0003723//RNA binding;GO:0030331//estrogen receptor binding;GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0046966//thyroid hormone receptor binding;GO:0044212//transcription regulatory region DNA binding;GO:0001227//transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0046965//retinoid X receptor binding;GO:0050681//androgen receptor binding;GO:0043565//sequence-specific DNA binding;GO:0008134//transcription factor binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0071391//cellular response to estrogen stimulus;GO:0006351//transcription, DNA-templated;GO:0045087//innate immune response","K19479//collagen, type X, alpha;K16628//collagen, type VII, alpha;K06676//condensin complex subunit 2;K07874//Ras-related protein Rab-1A;K00844//hexokinase [EC:2.7.1.1];K19720//collagen, type III, alpha;K19195//AT-rich interactive domain-containing protein 4B","NP_001306016.1//AT-rich interactive domain-containing protein 5A isoform b [Homo sapiens];NP_001306014.1//AT-rich interactive domain-containing protein 5A isoform a [Homo sapiens];AAA36325.1//modulator recognition factor I, partial [Homo sapiens]","1//3;2//1"]
[124783,1297,0.44,0.69,0.649092838140872,0.512174981681034,"*",0.357054,"SPATA32","GO:0048471//perinuclear region of cytoplasm","GO:0003779//actin binding","GO:0007283//spermatogenesis","NA","NP_689556.2//spermatogenesis-associated protein 32 [Homo sapiens]","2//1"]
[5721,829,90.47,141.85,0.64885477403787,{"v":2.14277010888889e-25,"d":"2.14E-25"},"*",{"v":7.24362e-27,"d":"7.24E-27"},"PSME2","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005654//nucleoplasm;GO:0000502//proteasome complex;GO:0005829//cytosol;GO:0008537//proteasome activator complex;GO:0005737//cytoplasm","GO:0061133//endopeptidase activator activity;GO:0042802//identical protein binding","GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:0043687//post-translational protein modification;GO:0038061//NIK/NF-kappaB signaling;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0006521//regulation of cellular amino acid metabolic process;GO:0010950//positive regulation of endopeptidase activity;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0016579//protein deubiquitination;GO:0043488//regulation of mRNA stability;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0000209//protein polyubiquitination;GO:0035722//interleukin-12-mediated signaling pathway;GO:0055085//transmembrane transport;GO:0000165//MAPK cascade;GO:0050852//T cell receptor signaling pathway;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0061136//regulation of proteasomal protein catabolic process;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:1902036//regulation of hematopoietic stem cell differentiation","K06697//proteasome activator subunit 2 (PA28 beta)","NP_002809.2//proteasome activator complex subunit 2 [Homo sapiens]","2//1"]
[5873,3455,4.28,6.71,0.648701969799036,{"v":8.23628424722041e-06,"d":"8.24E-06"},"*",{"v":1.576722e-06,"d":"1.58E-06"},"RAB27A","GO:0030425//dendrite;GO:0005770//late endosome;GO:0016324//apical plasma membrane;GO:0033093//Weibel-Palade body;GO:0042470//melanosome;GO:0005829//cytosol;GO:0005576//extracellular region;GO:0045202//synapse;GO:0070382//exocytic vesicle;GO:0070062//extracellular exosome;GO:0030667//secretory granule membrane;GO:0035580//specific granule lumen;GO:0032585//multivesicular body membrane;GO:0005764//lysosome;GO:0033162//melanosome membrane;GO:0001750//photoreceptor outer segment;GO:0030141//secretory granule;GO:0005794//Golgi apparatus","GO:0019904//protein domain specific binding;GO:0019003//GDP binding;GO:0031489//myosin V binding;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0048489//synaptic vesicle transport;GO:0007596//blood coagulation;GO:1903428//positive regulation of reactive oxygen species biosynthetic process;GO:0045921//positive regulation of exocytosis;GO:0050766//positive regulation of phagocytosis;GO:0043320//natural killer cell degranulation;GO:0036257//multivesicular body organization;GO:0043312//neutrophil degranulation;GO:0030318//melanocyte differentiation;GO:0006605//protein targeting;GO:0019882//antigen processing and presentation;GO:1903307//positive regulation of regulated secretory pathway;GO:0071985//multivesicular body sorting pathway;GO:0010628//positive regulation of gene expression;GO:0032400//melanosome localization;GO:0061024//membrane organization;GO:0043316//cytotoxic T cell degranulation;GO:0032402//melanosome transport;GO:0097278//complement-dependent cytotoxicity;GO:1990182//exosomal secretion;GO:0006887//exocytosis;GO:1903435//positive regulation of constitutive secretory pathway","K07885//Ras-related protein Rab-27A","NP_004571.2//ras-related protein Rab-27A [Homo sapiens]","4;2//1"]
[199746,741,35.32,55.28,0.646272272739792,{"v":1.76261137547272e-09,"d":"1.76E-09"},"*",{"v":2.04244e-10,"d":"2.04E-10"},"U2AF1L4","GO:0005654//nucleoplasm;GO:0089701//U2AF;GO:0005681//spliceosomal complex;GO:0016607//nuclear speck;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0046872//metal ion binding;GO:0030628//pre-mRNA 3'-splice site binding","GO:0006406//mRNA export from nucleus;GO:0000398//mRNA splicing, via spliceosome;GO:0006369//termination of RNA polymerase II transcription;GO:0031124//mRNA 3'-end processing;GO:0006405//RNA export from nucleus","K12836//splicing factor U2AF 35 kDa subunit","NP_659424.2//splicing factor U2AF 26 kDa subunit isoform 2 [Homo sapiens];NP_001035515.1//splicing factor U2AF 26 kDa subunit isoform 1 [Homo sapiens]","3//A2MP1;2//1"]
[100534599,5068,2.5,3.91,0.645240512645265,{"v":3.54899147399182e-05,"d":"3.55E-05"},"*",{"v":7.60276E-6,"d":"7.60E-06"},"ISY1-RAB43","NA","NA","NA","K12870//pre-mRNA-splicing factor ISY1","XP_001094091.1//PREDICTED: pre-mRNA-splicing factor ISY1 homolog [Macaca mulatta]","1//3"]
[5606,2318,39.64,61.96,0.64438018160308,{"v":1.40371165225225e-29,"d":"1.40E-29"},"*",{"v":3.90164E-31,"d":"3.90E-31"},"MAP2K3","GO:0016020//membrane;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005737//cytoplasm","GO:0004713//protein tyrosine kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004708//MAP kinase kinase activity;GO:0019901//protein kinase binding","GO:0023014//signal transduction by protein phosphorylation;GO:0042035//regulation of cytokine biosynthetic process;GO:0007165//signal transduction;GO:0007346//regulation of mitotic cell cycle;GO:0000187//activation of MAPK activity;GO:0032147//activation of protein kinase activity;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006954//inflammatory response;GO:0060048//cardiac muscle contraction;GO:0035897//proteolysis in other organism;GO:0045860//positive regulation of protein kinase activity;GO:0031098//stress-activated protein kinase signaling cascade;GO:0042981//regulation of apoptotic process","K04432//mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]","NP_659731.1//dual specificity mitogen-activated protein kinase kinase 3 isoform B [Homo sapiens];XP_016880346.1//PREDICTED: dual specificity mitogen-activated protein kinase kinase 3 isoform X2 [Homo sapiens]","4;1//3;2//1"]
[2006,3468,0.32,0.5,0.643856189774725,0.3127624346543,"*",0.18577,"ELN","GO:0031012//extracellular matrix;GO:0071953//elastic fiber;GO:0005576//extracellular region;GO:0005739//mitochondrion;GO:0005578//proteinaceous extracellular matrix","GO:0005201//extracellular matrix structural constituent;GO:0050840//extracellular matrix binding","GO:0030833//regulation of actin filament polymerization;GO:0022617//extracellular matrix disassembly;GO:0008015//blood circulation;GO:0007585//respiratory gaseous exchange;GO:0009887//animal organ morphogenesis;GO:0008283//cell proliferation;GO:0030198//extracellular matrix organization;GO:0007519//skeletal muscle tissue development;GO:0043149//stress fiber assembly","K14211//elastin","NP_001265845.1//elastin isoform j precursor [Homo sapiens];NP_001265842.1//elastin isoform g precursor [Homo sapiens];CAD98065.1//hypothetical protein, partial [Homo sapiens];NP_001075222.1//elastin isoform c precursor [Homo sapiens];NP_001265844.1//elastin isoform i precursor [Homo sapiens];NP_001075224.1//elastin isoform e precursor [Homo sapiens];NP_001265846.1//elastin isoform k precursor [Homo sapiens];NP_000492.2//elastin isoform a precursor [Homo sapiens];NP_001265841.1//elastin isoform f precursor [Homo sapiens];NP_001265868.1//elastin isoform m precursor [Homo sapiens];NP_001265847.1//elastin isoform l precursor [Homo sapiens];NP_001265843.1//elastin isoform h precursor [Homo sapiens];NP_001075223.1//elastin isoform d precursor [Homo sapiens]","1//3;3//A2MP1;2//1"]
[7357,4028,8.84,13.8,0.6425499922741,{"v":8.28301291704374e-13,"d":"8.28E-13"},"*",{"v":6.87572e-14,"d":"6.88E-14"},"UGCG","GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0016757//transferase activity, transferring glycosyl groups;GO:0102769//dihydroceramide glucosyltransferase activity;GO:0008120//ceramide glucosyltransferase activity","GO:0006688//glycosphingolipid biosynthetic process;GO:0006679//glucosylceramide biosynthetic process;GO:0008544//epidermis development;GO:1903955//positive regulation of protein targeting to mitochondrion;GO:0006687//glycosphingolipid metabolic process","K00720//ceramide glucosyltransferase [EC:2.4.1.80]","XP_011738666.1//PREDICTED: ceramide glucosyltransferase [Macaca nemestrina]","2//1"]
[57559,2094,9.08,14.17,0.642075555627104,{"v":3.47485673803731e-07,"d":"3.47E-07"},"*",{"v":5.36434e-08,"d":"5.36E-08"},"STAMBPL1","GO:0016020//membrane;GO:0005829//cytosol","GO:0061578//Lys63-specific deubiquitinase activity;GO:0046872//metal ion binding;GO:0008237//metallopeptidase activity","GO:0016579//protein deubiquitination","K11867//AMSH-like protease [EC:3.4.19.12]","NP_065850.1//AMSH-like protease [Homo sapiens]","3//A2MP1"]
[8798,970,27.29,42.56,0.641125756227049,{"v":1.68086696690179E-9,"d":"1.68E-09"},"*",{"v":1.9393E-10,"d":"1.94E-10"},"DYRK4","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0004713//protein tyrosine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0046872//metal ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding","NA","K18669//dual specificity tyrosine-phosphorylation-regulated kinase 2/3/4 [EC:2.7.12.1]","AAF91393.1//protein kinase DYRK4, partial [Homo sapiens];BAF85011.1//unnamed protein product [Homo sapiens];EAW88842.1//dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4, isoform CRA_b [Homo sapiens]","1//3;2//1"]
[345275,2289,1.18,1.84,0.640918906695172,0.0854714207464325,"*",0.0389956,"HSD17B13","GO:0005811//lipid droplet;GO:0005829//cytosol;GO:0005576//extracellular region","GO:0016491//oxidoreductase activity","GO:0034389//lipid particle organization;GO:0046889//positive regulation of lipid biosynthetic process","K15734//all-trans-retinol dehydrogenase (NAD+) [EC:1.1.1.105]","NP_835236.2//17-beta-hydroxysteroid dehydrogenase 13 isoform A precursor [Homo sapiens];NP_001129702.1//17-beta-hydroxysteroid dehydrogenase 13 isoform B [Homo sapiens]","4;2//1"]
[2742,3190,0.18,0.28,0.637429920615292,0.402849419031075,"*",0.26132,"GLRA2","GO:0042995//cell projection;GO:0005887//integral component of plasma membrane;GO:0030054//cell junction;GO:0034707//chloride channel complex;GO:0005886//plasma membrane;GO:0045211//postsynaptic membrane","GO:0022824//transmitter-gated ion channel activity;GO:0046872//metal ion binding;GO:0022852//glycine-gated chloride ion channel activity;GO:0016594//glycine binding;GO:0016934//extracellularly glycine-gated chloride channel activity","GO:0071361//cellular response to ethanol;GO:0043200//response to amino acid;GO:0034220//ion transmembrane transport;GO:0071294//cellular response to zinc ion;GO:0007218//neuropeptide signaling pathway;GO:0060012//synaptic transmission, glycinergic;GO:1902476//chloride transmembrane transport;GO:0071230//cellular response to amino acid stimulus","K05194//glycine receptor alpha-2","ERE65914.1//glycine receptor subunit alpha-2-like isoform 2 [Cricetulus griseus]","1//3;3//A2MP1"]
[10561,1742,0.09,0.14,0.637429920615292,0.781530372029968,"*",0.685686,"IFI44","GO:0005737//cytoplasm","NA","GO:0009615//response to virus","NA","NP_006408.3//interferon-induced protein 44 [Homo sapiens]",4]
[2695,711,6.39,9.94,0.637429920615292,0.0265994126587174,"*",0.01033404,"GIP","GO:0034774//secretory granule lumen;GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0043025//neuronal cell body","GO:0005179//hormone activity","GO:0014070//response to organic cyclic compound;GO:0043200//response to amino acid;GO:0032024//positive regulation of insulin secretion;GO:0070094//positive regulation of glucagon secretion;GO:0008344//adult locomotory behavior;GO:0050796//regulation of insulin secretion;GO:0010828//positive regulation of glucose transport;GO:0055123//digestive system development;GO:0070328//triglyceride homeostasis;GO:0060291//long-term synaptic potentiation;GO:0019233//sensory perception of pain;GO:0010269//response to selenium ion;GO:0009749//response to glucose;GO:0043950//positive regulation of cAMP-mediated signaling;GO:0033993//response to lipid;GO:0007565//female pregnancy;GO:0042493//response to drug;GO:0007165//signal transduction;GO:0048678//response to axon injury;GO:0043434//response to peptide hormone;GO:0031018//endocrine pancreas development;GO:0007613//memory;GO:0042594//response to starvation;GO:0035640//exploration behavior;GO:0010447//response to acidic pH","K05258//gastric inhibitory polypeptide","NP_004114.1//gastric inhibitory polypeptide preproprotein [Homo sapiens]","2//1"]
[6580,1921,0.27,0.42,0.637429920615292,0.48250390964792,"*",0.330298,"SLC22A1","GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane","GO:0008513//secondary active organic cation transmembrane transporter activity;GO:0015101//organic cation transmembrane transporter activity;GO:0008514//organic anion transmembrane transporter activity;GO:0015651//quaternary ammonium group transmembrane transporter activity;GO:0042803//protein homodimerization activity;GO:0005333//norepinephrine transmembrane transporter activity;GO:0005329//dopamine transmembrane transporter activity;GO:0005277//acetylcholine transmembrane transporter activity","GO:0015695//organic cation transport;GO:0048241//epinephrine transport;GO:0051260//protein homooligomerization;GO:0015874//norepinephrine transport;GO:0015872//dopamine transport;GO:0006836//neurotransmitter transport;GO:0006855//drug transmembrane transport;GO:0010248//establishment or maintenance of transmembrane electrochemical gradient","K08198//MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 1","XP_011831306.1//PREDICTED: solute carrier family 22 member 1 isoform X1 [Mandrillus leucophaeus];NP_694857.1//solute carrier family 22 member 1 isoform b [Homo sapiens]","1//3;2//1"]
[121268,1291,2.38,3.7,0.636563697208369,0.103084296478122,"*",0.0483736,"RHEBL1","GO:0016020//membrane;GO:0012505//endomembrane system;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0031929//TOR signaling;GO:0007165//signal transduction;GO:0051092//positive regulation of NF-kappaB transcription factor activity","K07849//Ras homolog enriched in brain like 1","NP_001290055.1//GTPase RhebL1 isoform 2 [Homo sapiens];NP_653194.1//GTPase RhebL1 isoform 1 precursor [Homo sapiens]","1//3;2//1"]
[54453,4265,7.36,11.44,0.636309380721376,{"v":1.37886134575119e-11,"d":"1.38E-11"},"*",{"v":1.269754E-12,"d":"1.27E-12"},"RIN2","GO:0005829//cytosol","GO:0017112//Rab guanyl-nucleotide exchange factor activity;GO:0030695//GTPase regulator activity;GO:0005096//GTPase activator activity","GO:0007165//signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0006897//endocytosis;GO:0061024//membrane organization","K17638//Ras and Rab interactor 1","XP_011527557.2//PREDICTED: ras and Rab interactor 2 isoform X1 [Homo sapiens];NP_001229510.1//ras and Rab interactor 2 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[253982,1562,6.73,10.45,0.634824532357928,0.0002777447302,"*",{"v":6.95492e-05,"d":"6.95E-05"},"ASPHD1","GO:0016021//integral component of membrane","GO:0051213//dioxygenase activity","GO:0018193//peptidyl-amino acid modification","K00476//aspartate beta-hydroxylase [EC:1.14.11.16]","NP_859069.2//aspartate beta-hydroxylase domain-containing protein 1 [Homo sapiens]","3//A2MP1"]
[100289187,1549,0.67,1.04,0.63435052768332,0.366854845710821,"*",0.227292,"TMEM225B","GO:0016021//integral component of membrane","NA","GO:0010923//negative regulation of phosphatase activity","NA","XP_011513993.1//PREDICTED: transmembrane protein 225-like isoform X1 [Homo sapiens]","2//1"]
[2120,5989,3.72,5.77,0.633268697537451,{"v":3.28642751269036e-08,"d":"3.29E-08"},"*",{"v":4.4583e-09,"d":"4.46E-09"},"ETV6","GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005829//cytosol","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0019904//protein domain specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0001227//transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0022008//neurogenesis;GO:0071425//hematopoietic stem cell proliferation;GO:0030154//cell differentiation;GO:0007296//vitellogenesis;GO:0097152//mesenchymal cell apoptotic process","K03211//ETS translocation variant 6/7","NP_001978.1//transcription factor ETV6 [Homo sapiens]",4]
[2357,1334,0.98,1.52,0.633217669328377,0.280984461058109,"*",0.1622512,"FPR1","GO:0030667//secretory granule membrane;GO:0005887//integral component of plasma membrane;GO:0101003//ficolin-1-rich granule membrane;GO:0005622//intracellular;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0035577//azurophil granule membrane","GO:0050786//RAGE receptor binding;GO:0005124//scavenger receptor binding;GO:0004875//complement receptor activity;GO:0004982//N-formyl peptide receptor activity","GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007165//signal transduction;GO:0000187//activation of MAPK activity;GO:0050900//leukocyte migration;GO:0007263//nitric oxide mediated signal transduction;GO:0006954//inflammatory response;GO:0002430//complement receptor mediated signaling pathway;GO:0060326//cell chemotaxis;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0043312//neutrophil degranulation;GO:0006935//chemotaxis;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway","K04172//formyl peptide receptor 1","NP_002020.1//fMet-Leu-Phe receptor [Homo sapiens]","1//3;3//A2MP1"]
[642843,647,1.18,1.83,0.633056788922201,0.453425674479167,"*",0.305198,"CPSF4L","NA","NA","NA","K14404//cleavage and polyadenylation specificity factor subunit 4","XP_011523417.1//PREDICTED: putative cleavage and polyadenylation specificity factor subunit 4-like protein isoform X1 [Homo sapiens]","1//3"]
[126326,4317,0.2,0.31,0.632268215499513,0.404609975894321,"*",0.26269,"GIPC3","NA","NA","NA","K20056//PDZ domain-containing protein GIPC","XP_005259549.1//PREDICTED: PDZ domain-containing protein GIPC3 isoform X1 [Homo sapiens]","2//1"]
[79883,3137,0.4,0.62,0.632268215499513,0.32906739949927,"*",0.1974734,"PODNL1","GO:0005737//cytoplasm;GO:0005578//proteinaceous extracellular matrix","GO:0004860//protein kinase inhibitor activity","GO:0006469//negative regulation of protein kinase activity;GO:0046426//negative regulation of JAK-STAT cascade;GO:0019221//cytokine-mediated signaling pathway","K08119//extracellular matrix protein 2","NP_079101.3//podocan-like protein 1 isoform 1 precursor [Homo sapiens];NP_001139727.1//podocan-like protein 1 isoform 3 precursor [Homo sapiens];NP_001139726.1//podocan-like protein 1 isoform 2 precursor [Homo sapiens]","4;1//3"]
[1390,1613,12.05,18.67,0.631688781108878,{"v":8.97462155307263e-10,"d":"8.97E-10"},"*",{"v":1.00567E-10,"d":"1.01E-10"},"CREM","GO:0005634//nucleus;GO:0005667//transcription factor complex;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0008140//cAMP response element binding protein binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0001227//transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding","GO:0006006//glucose metabolic process;GO:0007165//signal transduction;GO:0030154//cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0048384//retinoic acid receptor signaling pathway;GO:0006351//transcription, DNA-templated;GO:0007283//spermatogenesis;GO:0048511//rhythmic process;GO:0006687//glycosphingolipid metabolic process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0042752//regulation of circadian rhythm;GO:0006631//fatty acid metabolic process;GO:0007275//multicellular organism development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter","K09052//cAMP response element modulator","NP_001254498.1//cAMP-responsive element modulator isoform 30 [Homo sapiens];NP_853549.1//cAMP-responsive element modulator isoform 1 [Homo sapiens];NP_898831.1//cAMP-responsive element modulator isoform 19 [Homo sapiens];XP_008998429.1//PREDICTED: cAMP-responsive element modulator isoform X22 [Callithrix jacchus];NP_898829.1//cAMP-responsive element modulator isoform 21 [Homo sapiens];XP_006717445.1//PREDICTED: cAMP-responsive element modulator isoform X13 [Homo sapiens];XP_017818215.1//cAMP-responsive element modulator isoform X35 [Papio anubis];XP_016818486.1//PREDICTED: cAMP-responsive element modulator isoform X2 [Pan troglodytes];NP_001254499.1//cAMP-responsive element modulator isoform 31 [Homo sapiens];XP_008998428.1//PREDICTED: cAMP-responsive element modulator isoform X21 [Callithrix jacchus];XP_003468673.3//PREDICTED: cAMP-responsive element modulator isoform X7 [Cavia porcellus];NP_877573.1//cAMP-responsive element modulator isoform 16 [Homo sapiens];XP_005003284.2//PREDICTED: cAMP-responsive element modulator isoform X10 [Cavia porcellus];NP_001254494.1//cAMP-responsive element modulator isoform 26 [Homo sapiens];NP_001254491.1//cAMP-responsive element modulator isoform 23 [Homo sapiens];NP_001254493.1//cAMP-responsive element modulator isoform 25 [Homo sapiens];EAW85916.1//cAMP responsive element modulator, isoform CRA_a [Homo sapiens];XP_008998430.1//PREDICTED: cAMP-responsive element modulator isoform X23 [Callithrix jacchus];XP_008965826.1//PREDICTED: cAMP-responsive element modulator isoform X5 [Pan paniscus];NP_877572.1//cAMP-responsive element modulator isoform 15 [Homo sapiens];NP_001254495.1//cAMP-responsive element modulator isoform 27 [Homo sapiens];NP_898830.1//cAMP-responsive element modulator isoform 20 [Homo sapiens];AAC60617.2//cyclic AMP-responsive element modulator beta isoform [Homo sapiens];NP_001254497.1//cAMP-responsive element modulator isoform 29 [Homo sapiens];NP_874393.1//cAMP-responsive element modulator isoform 11 [Homo sapiens];XP_005003283.2//PREDICTED: cAMP-responsive element modulator isoform X8 [Cavia porcellus];NP_874390.1//cAMP-responsive element modulator isoform 8 [Homo sapiens];XP_021568059.1//cAMP-responsive element modulator isoform X9 [Carlito syrichta];NP_898883.1//cAMP-responsive element modulator isoform 22 [Homo sapiens];XP_008998431.1//PREDICTED: cAMP-responsive element modulator isoform X24 [Callithrix jacchus]","1//3;3//A2MP1;2//1"]
[221481,1150,0.71,1.1,0.631612594019978,0.475806426289701,"*",0.324492,"ARMC12","GO:0005634//nucleus","NA","NA","NA","NP_659465.2//armadillo repeat-containing protein 12 isoform a [Homo sapiens];NP_001273505.1//armadillo repeat-containing protein 12 isoform c [Homo sapiens];NP_001273503.1//armadillo repeat-containing protein 12 isoform b [Homo sapiens]","4;1//3"]
[602,1864,113.75,176.11,0.630610286292771,{"v":9.31566982972973e-69,"d":"9.32E-69"},"*",{"v":8.63102e-71,"d":"8.63E-71"},"BCL3","NA","NA","NA","K09258//B-cell CLL/lymphoma protein 3","XP_011525499.2//PREDICTED: B-cell lymphoma 3 protein isoform X1 [Homo sapiens]",4]
[26024,5505,3.79,5.86,0.628702816251156,{"v":1.4859968207748e-07,"d":"1.49E-07"},"*",{"v":2.18518e-08,"d":"2.19E-08"},"PTCD1","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0003723//RNA binding;GO:0000049//tRNA binding","GO:0042780//tRNA 3'-end processing","K17710//pentatricopeptide repeat domain-containing protein 1","NP_001185808.1//ATP5J2-PTCD1 fusion protein [Homo sapiens]","3//A2MP1"]
[84696,1471,1.21,1.87,0.628031222613042,0.204252000420266,"*",0.1095294,"ABHD1","GO:0016021//integral component of membrane","GO:0016787//hydrolase activity;GO:0052689//carboxylic ester hydrolase activity;GO:0016298//lipase activity","GO:0044255//cellular lipid metabolic process","K13696//abhydrolase domain-containing protein 1/3","XP_011806780.1//PREDICTED: abhydrolase domain-containing protein 1 [Colobus angolensis palliatus]","3//A2MP1"]
[4163,8262,0.11,0.17,0.628031222613042,0.404570966062476,"*",0.26269,"MCC","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0030027//lamellipodium;GO:0005737//cytoplasm","GO:0004872//receptor activity","GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0045184//establishment of protein localization;GO:0007165//signal transduction;GO:0016055//Wnt signaling pathway;GO:0050680//negative regulation of epithelial cell proliferation;GO:0010633//negative regulation of epithelial cell migration","K21881//Usher syndrome type-1C protein-binding protein 1","NP_002378.1//colorectal mutant cancer protein isoform 2 [Homo sapiens];NP_001078846.1//colorectal mutant cancer protein isoform 1 [Homo sapiens]","1//3;2//1"]
[5979,4114,0.11,0.17,0.628031222613042,0.745427889661164,"*",0.644538,"RET","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0010008//endosome membrane;GO:0030425//dendrite;GO:0030424//axon;GO:0098797//plasma membrane protein complex;GO:0043235//receptor complex;GO:0043025//neuronal cell body;GO:0005887//integral component of plasma membrane;GO:0045121//membrane raft;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005769//early endosome","GO:0004713//protein tyrosine kinase activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005524//ATP binding;GO:0004872//receptor activity;GO:0005509//calcium ion binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity","GO:0030335//positive regulation of cell migration;GO:0061146//Peyer's patch morphogenesis;GO:0033619//membrane protein proteolysis;GO:0007411//axon guidance;GO:0007158//neuron cell-cell adhesion;GO:0035799//ureter maturation;GO:0042493//response to drug;GO:0007165//signal transduction;GO:0001755//neural crest cell migration;GO:0006468//protein phosphorylation;GO:0045793//positive regulation of cell size;GO:0071300//cellular response to retinoic acid;GO:0033141//positive regulation of peptidyl-serine phosphorylation of STAT protein;GO:2001241//positive regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0060041//retina development in camera-type eye;GO:0045893//positive regulation of transcription, DNA-templated;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0014042//positive regulation of neuron maturation;GO:0048265//response to pain;GO:0050770//regulation of axonogenesis;GO:0030155//regulation of cell adhesion;GO:0097021//lymphocyte migration into lymphoid organs;GO:0001838//embryonic epithelial tube formation;GO:0000165//MAPK cascade;GO:0060384//innervation;GO:0007497//posterior midgut development;GO:0010976//positive regulation of neuron projection development;GO:0048484//enteric nervous system development;GO:0001657//ureteric bud development;GO:0042551//neuron maturation;GO:0033630//positive regulation of cell adhesion mediated by integrin;GO:0072300//positive regulation of metanephric glomerulus development","K05126//proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]","NP_065681.1//proto-oncogene tyrosine-protein kinase receptor Ret isoform c precursor [Homo sapiens];NP_066124.1//proto-oncogene tyrosine-protein kinase receptor Ret isoform a precursor [Homo sapiens]","1//3;5"]
[266812,2338,0.44,0.68,0.628031222613042,0.366780726133953,"*",0.227292,"NAP1L5","GO:0005634//nucleus","NA","GO:0006334//nucleosome assembly","K19475//WAS/WASL-interacting protein","XP_011230419.1//PREDICTED: nucleosome assembly protein 1-like 5 [Ailuropoda melanoleuca]","3//A2MP1"]
[64167,5285,0.92,1.42,0.626185163447669,0.0146429441484565,"*",5.28554E-3,"ERAP2","GO:0005788//endoplasmic reticulum lumen;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005737//cytoplasm;GO:0005886//plasma membrane","GO:0004175//endopeptidase activity;GO:0008237//metallopeptidase activity;GO:0004177//aminopeptidase activity;GO:0008270//zinc ion binding;GO:0042277//peptide binding;GO:0070006//metalloaminopeptidase activity","GO:0008217//regulation of blood pressure;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0043171//peptide catabolic process;GO:0019885//antigen processing and presentation of endogenous peptide antigen via MHC class I;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0002250//adaptive immune response;GO:0006508//proteolysis","K13723//endoplasmic reticulum aminopeptidase 2 [EC:3.4.11.-]","NP_071745.1//endoplasmic reticulum aminopeptidase 2 isoform 1 [Homo sapiens];NP_001316162.1//endoplasmic reticulum aminopeptidase 2 isoform 3 [Homo sapiens];NP_001316158.1//endoplasmic reticulum aminopeptidase 2 isoform 2 [Homo sapiens]","4;1//3;2//1"]
[84436,3995,0.46,0.71,0.626185163447669,0.174873606976185,"*",0.0910166,"ZNF528","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_018871773.1//PREDICTED: zinc finger protein 528 isoform X1 [Gorilla gorilla gorilla]","2//1"]
[4824,3067,2.95,4.55,0.625151590836855,0.00205204047811448,"*",0.000610448,"NKX3-1","GO:0005634//nucleus;GO:0005622//intracellular","GO:0030331//estrogen receptor binding;GO:0030284//estrogen receptor activity;GO:0004882//androgen receptor activity;GO:0001047//core promoter binding","GO:0060442//branching involved in prostate gland morphogenesis;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0030521//androgen receptor signaling pathway;GO:0048754//branching morphogenesis of an epithelial tube","K09348//homeobox protein Nkx-3.1","NP_001243268.1//homeobox protein Nkx-3.1 isoform 2 [Homo sapiens];NP_006158.2//homeobox protein Nkx-3.1 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[147807,1144,15.59,24.03,0.624215720432082,{"v":2.50295586382979E-6,"d":"2.50E-06"},"*",{"v":4.41864e-07,"d":"4.42E-07"},"ZNF524","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_014712194.1//PREDICTED: zinc finger protein 865 [Equus asinus]","3//A2MP1"]
[55850,877,4.73,7.28,0.622098266859301,0.0393996274939024,"*",0.01618014,"USE1","NA","NA","NA","K08507//unconventional SNARE in the endoplasmic reticulum protein 1","XP_004060298.1//PREDICTED: vesicle transport protein USE1 [Gorilla gorilla gorilla]","3//A2MP1"]
[23179,4928,0.13,0.2,0.62148837674627,0.429971245761909,"*",0.284216,"RGL1","GO:0005829//cytosol;GO:0005622//intracellular","GO:0008321//Ral guanyl-nucleotide exchange factor activity","GO:0007264//small GTPase mediated signal transduction;GO:0019216//regulation of lipid metabolic process","K17635//ral guanine nucleotide dissociation stimulator-like 1","NP_001284599.1//ral guanine nucleotide dissociation stimulator-like 1 isoform 2 [Homo sapiens];XP_007987407.1//PREDICTED: ral guanine nucleotide dissociation stimulator-like 1 isoform X1 [Chlorocebus sabaeus];NP_055964.3//ral guanine nucleotide dissociation stimulator-like 1 isoform 1 [Homo sapiens]","4;1//3"]
[57731,8705,0.39,0.6,0.62148837674627,0.126887306989317,"*",0.061712,"SPTBN4","GO:0016020//membrane;GO:0043194//axon initial segment;GO:0005737//cytoplasm;GO:0043025//neuronal cell body;GO:0005829//cytosol;GO:0014704//intercalated disc;GO:0005886//plasma membrane;GO:0070062//extracellular exosome;GO:0016605//PML body;GO:0043203//axon hillock;GO:0070852//cell body fiber;GO:0016363//nuclear matrix;GO:0005912//adherens junction;GO:0033270//paranode region of axon;GO:0008091//spectrin;GO:0033268//node of Ranvier","GO:0003779//actin binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0019902//phosphatase binding;GO:0005200//structural constituent of cytoskeleton;GO:0030506//ankyrin binding;GO:0030507//spectrin binding;GO:0005543//phospholipid binding","GO:0002028//regulation of sodium ion transport;GO:0019226//transmission of nerve impulse;GO:0007016//cytoskeletal anchoring at plasma membrane;GO:0033135//regulation of peptidyl-serine phosphorylation;GO:0010459//negative regulation of heart rate;GO:0016192//vesicle-mediated transport;GO:0007411//axon guidance;GO:0051693//actin filament capping;GO:0061337//cardiac conduction;GO:0000165//MAPK cascade;GO:0009566//fertilization;GO:0072659//protein localization to plasma membrane;GO:0045162//clustering of voltage-gated sodium channels;GO:0007409//axonogenesis;GO:0007605//sensory perception of sound;GO:0007628//adult walking behavior;GO:0021952//central nervous system projection neuron axonogenesis;GO:0040018//positive regulation of multicellular organism growth;GO:0006888//ER to Golgi vesicle-mediated transport","K06115//spectrin beta","EAW56975.1//spectrin, beta, non-erythrocytic 4, isoform CRA_c [Homo sapiens];NP_066022.2//spectrin beta chain, non-erythrocytic 4 isoform sigma1 [Homo sapiens]","2//1"]
[4313,3152,1.84,2.83,0.621096286774869,0.0101940435549133,"*",3.53288E-3,"MMP2","GO:0031012//extracellular matrix;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0030017//sarcomere;GO:0005578//proteinaceous extracellular matrix;GO:0005576//extracellular region;GO:0005739//mitochondrion;GO:0005886//plasma membrane","GO:0004252//serine-type endopeptidase activity;GO:0008237//metallopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding","GO:0045089//positive regulation of innate immune response;GO:0035987//endodermal cell differentiation;GO:1904707//positive regulation of vascular smooth muscle cell proliferation;GO:0007566//embryo implantation;GO:0044267//cellular protein metabolic process;GO:0060346//bone trabecula formation;GO:0001525//angiogenesis;GO:0048013//ephrin receptor signaling pathway;GO:0001957//intramembranous ossification;GO:0001955//blood vessel maturation;GO:0071230//cellular response to amino acid stimulus;GO:0001666//response to hypoxia;GO:0022617//extracellular matrix disassembly;GO:0006508//proteolysis;GO:0060325//face morphogenesis;GO:0030574//collagen catabolic process","K01398//matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]","NP_001121363.1//72 kDa type IV collagenase isoform 2 [Homo sapiens];NP_004521.1//72 kDa type IV collagenase isoform 1 preproprotein [Homo sapiens]","1//3;2//1;5"]
[148327,1783,3.7,5.69,0.62090338179027,1.94385681014799E-3,"*",0.000575588,"CREB3L4","GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0005783//endoplasmic reticulum;GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005739//mitochondrion","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0035497//cAMP response element binding","GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007283//spermatogenesis;GO:0030968//endoplasmic reticulum unfolded protein response","K09048//cyclic AMP-responsive element-binding protein 3","NP_001242909.1//cyclic AMP-responsive element-binding protein 3-like protein 4 isoform 2 [Homo sapiens];NP_570968.1//cyclic AMP-responsive element-binding protein 3-like protein 4 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[84258,2493,0.67,1.03,0.620411336725446,0.37583767179178,"*",0.234128,"SYT3","GO:0030658//transport vesicle membrane;GO:0005768//endosome;GO:0098793//presynapse;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005544//calcium-dependent phospholipid binding;GO:0030276//clathrin binding;GO:0005509//calcium ion binding;GO:0019905//syntaxin binding","GO:0006906//vesicle fusion;GO:1903861//positive regulation of dendrite extension;GO:0048791//calcium ion-regulated exocytosis of neurotransmitter;GO:0017158//regulation of calcium ion-dependent exocytosis;GO:0017156//calcium ion regulated exocytosis","K19903//synaptotagmin-3","XP_018872170.1//PREDICTED: synaptotagmin-3 isoform X1 [Gorilla gorilla gorilla]","1//3;2//1"]
[27242,3646,23.16,35.6,0.620241987864524,{"v":4.0220240647541E-27,"d":"4.02E-27"},"*",{"v":1.228714E-28,"d":"1.23E-28"},"TNFRSF21","GO:0030424//axon;GO:0031226//intrinsic component of plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005031//tumor necrosis factor-activated receptor activity","GO:0048713//regulation of oligodendrocyte differentiation;GO:2001180//negative regulation of interleukin-10 secretion;GO:0051402//neuron apoptotic process;GO:0097190//apoptotic signaling pathway;GO:0042127//regulation of cell proliferation;GO:2000663//negative regulation of interleukin-5 secretion;GO:0032496//response to lipopolysaccharide;GO:0071356//cellular response to tumor necrosis factor;GO:0042130//negative regulation of T cell proliferation;GO:0006959//humoral immune response;GO:0019216//regulation of lipid metabolic process;GO:0097252//oligodendrocyte apoptotic process;GO:0031642//negative regulation of myelination;GO:0042552//myelination;GO:0001783//B cell apoptotic process;GO:0007165//signal transduction;GO:0050852//T cell receptor signaling pathway;GO:2000666//negative regulation of interleukin-13 secretion;GO:0002250//adaptive immune response;GO:0006915//apoptotic process;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0030889//negative regulation of B cell proliferation;GO:0042981//regulation of apoptotic process","K05157//tumor necrosis factor receptor superfamily member 21","XP_003128478.3//tumor necrosis factor receptor superfamily member 21 [Sus scrofa]",4]
[154467,637,19.45,29.83,0.616993822461658,0.000183895724380165,"*",{"v":4.45752E-5,"d":"4.46E-05"},"CCDC167","GO:0016021//integral component of membrane","NA","NA","NA","AAF28943.1//HSPC265, partial [Homo sapiens]","2//1"]
[56144,5170,0.6,0.92,0.616671360448494,0.116226464705113,"*",0.0556394,"PCDHA4","NA","NA","NA","K16493//protocadherin alpha","XP_017387687.1//PREDICTED: protocadherin alpha-4 [Cebus capucinus imitator];XP_012360376.1//PREDICTED: protocadherin alpha-4 isoform X12 [Nomascus leucogenys]","3//A2MP1;2//1"]
[6919,1273,6.68,10.24,0.616295707525948,0.0017872495601023,"*",0.000524964,"TCEA2","GO:0005634//nucleus;GO:0008023//transcription elongation factor complex","GO:0003677//DNA binding;GO:0003746//translation elongation factor activity;GO:0008270//zinc ion binding;GO:0003676//nucleic acid binding","GO:0032784//regulation of DNA-templated transcription, elongation;GO:0006355//regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006354//DNA-templated transcription, elongation;GO:0006351//transcription, DNA-templated","K03145//transcription elongation factor S-II","XP_008960554.1//PREDICTED: transcription elongation factor A protein 2 isoform X2 [Pan paniscus]","2//1;5"]
[116541,628,17.58,26.91,0.614207320497014,0.000490152706151645,"*",0.0001286904,"MRPL54","GO:0005762//mitochondrial large ribosomal subunit;GO:0005743//mitochondrial inner membrane","GO:0003723//RNA binding","GO:0070126//mitochondrial translational termination;GO:0070125//mitochondrial translational elongation","K17435//large subunit ribosomal protein L54","NP_758455.1//39S ribosomal protein L54, mitochondrial [Homo sapiens]","2//1"]
[63970,970,0.49,0.75,0.614108846380673,0.629047590254534,"*",0.505908,"TP53AIP1","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","NA","GO:0042981//regulation of apoptotic process;GO:0006915//apoptotic process","K13773//p53-regulated apoptosis-inducing protein 1","XP_011908764.1//PREDICTED: p53-regulated apoptosis-inducing protein 1 isoform X1 [Cercocebus atys];XP_016873606.1//PREDICTED: p53-regulated apoptosis-inducing protein 1 isoform X5 [Homo sapiens];XP_016873602.1//PREDICTED: p53-regulated apoptosis-inducing protein 1 isoform X1 [Homo sapiens];XP_016873603.1//PREDICTED: p53-regulated apoptosis-inducing protein 1 isoform X2 [Homo sapiens]","1//3;2//1"]
[56931,2127,12.14,18.58,0.613982080126971,{"v":1.23015471432734e-08,"d":"1.23E-08"},"*",{"v":1.585632e-09,"d":"1.59E-09"},"DUS3L","NA","GO:0003723//RNA binding;GO:0046872//metal ion binding;GO:0017150//tRNA dihydrouridine synthase activity;GO:0050660//flavin adenine dinucleotide binding","NA","K05544//tRNA-dihydrouridine synthase 3 [EC:1.3.1.89]","NP_064560.2//tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like isoform 1 [Homo sapiens];NP_001155091.1//tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like isoform 2 [Homo sapiens]","1//3;2//1"]
[161725,2411,0.17,0.26,0.612976876890753,0.718782444179815,"*",0.60458,"OTUD7A","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0070530//K63-linked polyubiquitin modification-dependent protein binding;GO:0004843//thiol-dependent ubiquitin-specific protease activity;GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0036459//thiol-dependent ubiquitinyl hydrolase activity","GO:0050727//regulation of inflammatory response;GO:0071108//protein K48-linked deubiquitination;GO:0071947//protein deubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination;GO:0006955//immune response;GO:0045088//regulation of innate immune response;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0070536//protein K63-linked deubiquitination;GO:0035871//protein K11-linked deubiquitination","K11860//OTU domain-containing protein 7 [EC:3.4.19.12]","NP_001316836.1//OTU domain-containing protein 7A isoform 2 [Homo sapiens];NP_570971.1//OTU domain-containing protein 7A isoform 1 [Homo sapiens]","1//3;2//1"]
[6273,970,2.89,4.42,0.612976876890753,0.109311861568886,"*",0.051905,"S100A2","NA","GO:0042802//identical protein binding;GO:0005509//calcium ion binding;GO:0046914//transition metal ion binding","GO:0043542//endothelial cell migration","K21128//protein S100-A9;K17274//calpactin-1 light chain","P29034.3//RecName: Full=Protein S100-A2; AltName: Full=CAN19; AltName: Full=Protein S-100L; AltName: Full=S100 calcium-binding protein A2","3//A2MP1"]
[4013,1874,0.17,0.26,0.612976876890753,0.666116652986498,"*",0.546646,"VWA5A","NA","NA","NA","K10798//poly [ADP-ribose] polymerase [EC:2.4.2.30]","XP_011541130.1//PREDICTED: von Willebrand factor A domain-containing protein 5A isoform X1 [Homo sapiens]","1//3;4;2//1"]
[27120,1018,0.17,0.26,0.612976876890753,0.780361083214591,"*",0.685686,"DKKL1","GO:0005615//extracellular space;GO:0001669//acrosomal vesicle","GO:0004871//signal transducer activity","GO:0043065//positive regulation of apoptotic process;GO:0009653//anatomical structure morphogenesis;GO:2000225//negative regulation of testosterone biosynthetic process;GO:0007341//penetration of zona pellucida;GO:0045600//positive regulation of fat cell differentiation","K13911//basic salivary proline-rich protein 1/2;K14398//cleavage and polyadenylation specificity factor subunit 6/7;K11448//lysine-specific demethylase 6B [EC:1.14.11.-]","XP_011525026.1//PREDICTED: dickkopf-like protein 1 isoform X1 [Homo sapiens];NP_001184230.1//dickkopf-like protein 1 isoform 2 precursor [Homo sapiens];NP_055234.1//dickkopf-like protein 1 isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[6909,3396,2.57,3.93,0.612760953064729,1.59876841411967E-3,"*",4.64998E-4,"TBX2","GO:0005634//nucleus;GO:0005667//transcription factor complex","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0003148//outflow tract septum morphogenesis;GO:0060596//mammary placode formation;GO:0048738//cardiac muscle tissue development;GO:0042733//embryonic digit morphogenesis;GO:0035909//aorta morphogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0060560//developmental growth involved in morphogenesis;GO:0007521//muscle cell fate determination;GO:0090398//cellular senescence;GO:0008016//regulation of heart contraction;GO:0003203//endocardial cushion morphogenesis;GO:0060021//palate development;GO:0048596//embryonic camera-type eye morphogenesis;GO:0003256//regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0007569//cell aging;GO:0006351//transcription, DNA-templated;GO:0035050//embryonic heart tube development;GO:1901211//negative regulation of cardiac chamber formation;GO:0003151//outflow tract morphogenesis;GO:0001947//heart looping;GO:0060465//pharynx development;GO:0007219//Notch signaling pathway;GO:1901208//negative regulation of heart looping;GO:0008284//positive regulation of cell proliferation;GO:0036302//atrioventricular canal development","K10176//T-box protein 2","NP_005985.3//T-box transcription factor TBX2 [Homo sapiens]","3//A2MP1"]
[3606,1160,26.54,40.58,0.612600494386466,{"v":5.91983120731011e-10,"d":"5.92E-10"},"*",{"v":6.48906e-11,"d":"6.49E-11"},"IL18","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005576//extracellular region","GO:0005125//cytokine activity","GO:0010744//positive regulation of macrophage derived foam cell differentiation;GO:0045630//positive regulation of T-helper 2 cell differentiation;GO:0042253//granulocyte macrophage colony-stimulating factor biosynthetic process;GO:0032740//positive regulation of interleukin-17 production;GO:0042231//interleukin-13 biosynthetic process;GO:0070328//triglyceride homeostasis;GO:0035744//T-helper 1 cell cytokine production;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0032729//positive regulation of interferon-gamma production;GO:0042104//positive regulation of activated T cell proliferation;GO:0001525//angiogenesis;GO:0042267//natural killer cell mediated cytotoxicity;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0035655//interleukin-18-mediated signaling pathway;GO:0032725//positive regulation of granulocyte macrophage colony-stimulating factor production;GO:0045662//negative regulation of myoblast differentiation;GO:0030101//natural killer cell activation;GO:0042033//chemokine biosynthetic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0032148//activation of protein kinase B activity;GO:0051897//positive regulation of protein kinase B signaling;GO:0042092//type 2 immune response;GO:0034105//positive regulation of tissue remodeling;GO:0050729//positive regulation of inflammatory response;GO:0032819//positive regulation of natural killer cell proliferation;GO:0042094//interleukin-2 biosynthetic process;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0071407//cellular response to organic cyclic compound;GO:0008283//cell proliferation;GO:0042088//T-helper 1 type immune response;GO:0042632//cholesterol homeostasis;GO:0030155//regulation of cell adhesion;GO:0000165//MAPK cascade;GO:0042119//neutrophil activation;GO:0007267//cell-cell signaling;GO:0032635//interleukin-6 production;GO:0006954//inflammatory response;GO:0042346//positive regulation of NF-kappaB import into nucleus;GO:0051142//positive regulation of NK T cell proliferation;GO:0042095//interferon-gamma biosynthetic process;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0030431//sleep;GO:0006955//immune response","K05482//interleukin 18","NP_001230140.1//interleukin-18 isoform 2 [Homo sapiens];NP_001553.1//interleukin-18 isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[3107,1586,29.73,45.44,0.612043371597038,{"v":8.68853304317181e-15,"d":"8.69E-15"},"*",{"v":6.17346e-16,"d":"6.17E-16"},"HLA-C","NA","NA","NA","K06751//major histocompatibility complex, class I","SBW38606.1//MHC class I antigen [Homo sapiens];ANJ45904.1//MHC class I antigen [Homo sapiens]","1//3;5"]
[137994,2495,3.37,5.15,0.611823840888722,0.00104804660106857,"*",0.000294718,"LETM2","GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion","GO:0043022//ribosome binding","GO:0006875//cellular metal ion homeostasis","K12581//CCR4-NOT transcription complex subunit 7/8;K11447//histone demethylase [EC:1.14.11.-];K17800//LETM1 and EF-hand domain-containing protein 1, mitochondrial","NP_001273750.1//LETM1 domain-containing protein LETM2, mitochondrial isoform 5 [Homo sapiens];EAW63318.1//leucine zipper-EF-hand containing transmembrane protein 2, isoform CRA_b, partial [Homo sapiens];NP_001273748.1//LETM1 domain-containing protein LETM2, mitochondrial isoform 4 [Homo sapiens];NP_001317444.1//LETM1 domain-containing protein LETM2, mitochondrial isoform 6 [Homo sapiens];XP_011542711.1//PREDICTED: LETM1 domain-containing protein LETM2, mitochondrial isoform X5 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[79058,1889,17.52,26.76,0.611075341040288,{"v":8.43568384343434e-11,"d":"8.44E-11"},"*",{"v":8.36492e-12,"d":"8.36E-12"},"ASPSCR1","GO:0043231//intracellular membrane-bounded organelle;GO:0005654//nucleoplasm;GO:0019898//extrinsic component of membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0048471//perinuclear region of cytoplasm;GO:0012505//endomembrane system;GO:0012506//vesicle membrane;GO:0005829//cytosol;GO:0009898//cytoplasmic side of plasma membrane;GO:0005886//plasma membrane","NA","GO:0006886//intracellular protein transport;GO:0031401//positive regulation of protein modification process;GO:0046324//regulation of glucose import;GO:0042593//glucose homeostasis","K15627//tether containing UBX domain for GLUT4","NP_076988.1//tether containing UBX domain for GLUT4 isoform 1 [Homo sapiens];NP_001238817.1//tether containing UBX domain for GLUT4 isoform 2 [Homo sapiens];XP_016880531.1//PREDICTED: tether containing UBX domain for GLUT4 isoform X6 [Homo sapiens]","1//3;3//A2MP1"]
[84174,2519,0.76,1.16,0.610053481683987,0.183461437569982,"*",0.0964166,"SLA2","GO:0043231//intracellular membrane-bounded organelle;GO:0010008//endosome membrane;GO:0005654//nucleoplasm;GO:0005770//late endosome;GO:0005737//cytoplasm;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane","GO:0005070//SH3/SH2 adaptor activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0047485//protein N-terminus binding;GO:0005102//receptor binding","GO:0042110//T cell activation;GO:0016477//cell migration;GO:0038083//peptidyl-tyrosine autophosphorylation;GO:0030154//cell differentiation;GO:0042127//regulation of cell proliferation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0030522//intracellular receptor signaling pathway;GO:0050869//negative regulation of B cell activation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0045087//innate immune response;GO:0050776//regulation of immune response;GO:0050851//antigen receptor-mediated signaling pathway;GO:0019724//B cell mediated immunity;GO:0050849//negative regulation of calcium-mediated signaling","K08890//B lymphoid tyrosine kinase [EC:2.7.10.2];K08893//hemopoietic cell kinase [EC:2.7.10.2]","NP_115590.1//src-like-adapter 2 isoform a [Homo sapiens];NP_778252.1//src-like-adapter 2 isoform b [Homo sapiens]","3//A2MP1;2//1"]
[5898,2828,11.16,17.02,0.608894009856775,{"v":3.20864854169131e-10,"d":"3.21E-10"},"*",{"v":3.39666e-11,"d":"3.40E-11"},"RALA","GO:0070062//extracellular exosome;GO:0005925//focal adhesion;GO:0005622//intracellular;GO:0043209//myelin sheath;GO:0030496//midbody;GO:0009986//cell surface;GO:0032154//cleavage furrow;GO:0030139//endocytic vesicle;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0030659//cytoplasmic vesicle membrane","GO:0004713//protein tyrosine kinase activity;GO:0019003//GDP binding;GO:0031625//ubiquitin protein ligase binding;GO:0017022//myosin binding;GO:0031755//Edg-2 lysophosphatidic acid receptor binding;GO:0005525//GTP binding;GO:0051117//ATPase binding;GO:0003924//GTPase activity","GO:0051665//membrane raft localization;GO:0031532//actin cytoskeleton reorganization;GO:0051491//positive regulation of filopodium assembly;GO:0061024//membrane organization;GO:0017157//regulation of exocytosis;GO:0051301//cell division;GO:0001843//neural tube closure;GO:0007049//cell cycle;GO:0007265//Ras protein signal transduction;GO:0006887//exocytosis","K07834//Ras-related protein Ral-A","XP_006143062.1//PREDICTED: ras-related protein Ral-A isoform X1 [Tupaia chinensis]","3//A2MP1"]
[6665,1394,1.22,1.86,0.608421473545145,0.235700079686626,"*",0.131838,"SOX15","GO:0005634//nucleus;GO:0044798//nuclear transcription factor complex;GO:0005737//cytoplasm","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0046982//protein heterodimerization activity;GO:0003700//DNA binding transcription factor activity","GO:0070318//positive regulation of G0 to G1 transition;GO:0043403//skeletal muscle tissue regeneration;GO:0030154//cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0045843//negative regulation of striated muscle tissue development;GO:2000288//positive regulation of myoblast proliferation;GO:0008584//male gonad development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0014718//positive regulation of satellite cell activation involved in skeletal muscle regeneration;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006325//chromatin organization;GO:0048627//myoblast development","K09271//transcription factor SOX15/30","NP_008873.1//protein SOX-15 [Homo sapiens]","1//3"]
[7076,931,189.14,288.36,0.608416552467734,{"v":1.92417183518519e-51,"d":"1.92E-51"},"*",{"v":2.60186E-53,"d":"2.60E-53"},"TIMP1","GO:0031093//platelet alpha granule lumen;GO:0070062//extracellular exosome;GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005578//proteinaceous extracellular matrix;GO:0005604//basement membrane","GO:0002020//protease binding;GO:0046872//metal ion binding;GO:0008083//growth factor activity;GO:0008191//metalloendopeptidase inhibitor activity;GO:0005125//cytokine activity;GO:0008270//zinc ion binding","GO:0043687//post-translational protein modification;GO:0010951//negative regulation of endopeptidase activity;GO:0034097//response to cytokine;GO:0051216//cartilage development;GO:0044267//cellular protein metabolic process;GO:0002576//platelet degranulation;GO:1905049//negative regulation of metallopeptidase activity;GO:1901164//negative regulation of trophoblast cell migration;GO:0043086//negative regulation of catalytic activity;GO:2001044//regulation of integrin-mediated signaling pathway;GO:0042060//wound healing;GO:0043434//response to peptide hormone;GO:0043066//negative regulation of apoptotic process;GO:0007568//aging;GO:0022617//extracellular matrix disassembly;GO:0001775//cell activation;GO:0009725//response to hormone;GO:0051045//negative regulation of membrane protein ectodomain proteolysis;GO:0008284//positive regulation of cell proliferation","K16451//metallopeptidase inhibitor 1","XP_012603832.1//metalloproteinase inhibitor 1 [Microcebus murinus]","2//1"]
[7286,3109,7,10.67,0.608133348992096,{"v":2.43927261690722e-07,"d":"2.44E-07"},"*",{"v":3.70304e-08,"d":"3.70E-08"},"TUFT1","GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0030345//structural constituent of tooth enamel","GO:0030282//bone mineralization;GO:0042476//odontogenesis","K22031//myocardial zonula adherens protein","NP_001288246.1//tuftelin isoform 3 [Homo sapiens];NP_001119809.1//tuftelin isoform 2 [Homo sapiens];NP_064512.1//tuftelin isoform 1 [Homo sapiens]","1//3;2//1"]
[94115,904,6.07,9.25,0.607756849147992,0.0175916956124005,"*",0.0065008,"CGB8","GO:0005576//extracellular region","GO:0005179//hormone activity","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0016486//peptide hormone processing;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0007292//female gamete generation;GO:0006915//apoptotic process","K10045//chorionic gonadotropin, beta polypeptide","Q6NT52.4//RecName: Full=Choriogonadotropin subunit beta variant 2; Flags: Precursor","2//1"]
[83638,1569,45.82,69.8,0.607249577792339,{"v":1.04068168558952e-21,"d":"1.04E-21"},"*",{"v":4.4757e-23,"d":"4.48E-23"},"C11orf68","NA","GO:0003723//RNA binding","NA","NA","NP_113638.2//UPF0696 protein C11orf68 isoform 2 [Homo sapiens];NP_001129107.1//UPF0696 protein C11orf68 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[4188,1728,0.23,0.35,0.605721060887954,0.695530726766499,"*",0.578622,"MDFI","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0042802//identical protein binding;GO:0008134//transcription factor binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0042994//cytoplasmic sequestering of transcription factor;GO:0030178//negative regulation of Wnt signaling pathway;GO:0060707//trophoblast giant cell differentiation;GO:0009950//dorsal/ventral axis specification;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0043392//negative regulation of DNA binding;GO:0048704//embryonic skeletal system morphogenesis;GO:0009790//embryo development","NA","NP_001287734.1//myoD family inhibitor isoform 2 [Homo sapiens];NP_005577.1//myoD family inhibitor isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[646915,2891,0.23,0.35,0.605721060887954,0.534720454209879,"*",0.380872,"ZNF806","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","NP_001342390.1//zinc finger protein 806 isoform 2 [Homo sapiens];XP_017715274.1//PREDICTED: zinc finger protein 285 isoform X1 [Rhinopithecus bieti]","1//3"]
[5691,809,190.75,290.13,0.605016423631182,{"v":3.11358867175573E-44,"d":"3.11E-44"},"*",{"v":5.1068e-46,"d":"5.11E-46"},"PSMB3","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0019774//proteasome core complex, beta-subunit complex;GO:0005737//cytoplasm","GO:0004298//threonine-type endopeptidase activity","GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process","K02735//20S proteasome subunit beta 3 [EC:3.4.25.1]","XP_004454988.1//PREDICTED: proteasome subunit beta type-3 [Dasypus novemcinctus]","3//A2MP1"]
[79012,3245,0.25,0.38,0.604071323668861,0.39095887689243,"*",0.245726,"CAMKV","GO:0005622//intracellular;GO:0005886//plasma membrane;GO:0030659//cytoplasmic vesicle membrane","GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0004683//calmodulin-dependent protein kinase activity;GO:0005516//calmodulin binding","GO:0018107//peptidyl-threonine phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0035556//intracellular signal transduction","K08812//CaM kinase-like vesicle-associated [EC:2.7.11.-]","NP_076951.2//caM kinase-like vesicle-associated protein isoform 1 [Homo sapiens];NP_001307076.1//caM kinase-like vesicle-associated protein isoform 2 [Homo sapiens]","1//3;4"]
[3929,1894,0.25,0.38,0.604071323668861,0.608665132647902,"*",0.452136,"LBP","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0009986//cell surface;GO:0005576//extracellular region","GO:0001530//lipopolysaccharide binding;GO:0071723//lipopeptide binding;GO:0005102//receptor binding;GO:0070891//lipoteichoic acid binding","GO:0002232//leukocyte chemotaxis involved in inflammatory response;GO:0032755//positive regulation of interleukin-6 production;GO:0050829//defense response to Gram-negative bacterium;GO:0071222//cellular response to lipopolysaccharide;GO:0032496//response to lipopolysaccharide;GO:0032720//negative regulation of tumor necrosis factor production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0002281//macrophage activation involved in immune response;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0050830//defense response to Gram-positive bacterium;GO:0045087//innate immune response;GO:0034142//toll-like receptor 4 signaling pathway;GO:0008228//opsonization;GO:0045919//positive regulation of cytolysis;GO:0090023//positive regulation of neutrophil chemotaxis;GO:0043032//positive regulation of macrophage activation;GO:0032490//detection of molecule of bacterial origin;GO:0032757//positive regulation of interleukin-8 production;GO:0006953//acute-phase response;GO:0071223//cellular response to lipoteichoic acid;GO:0002224//toll-like receptor signaling pathway;GO:0006968//cellular defense response;GO:0042535//positive regulation of tumor necrosis factor biosynthetic process;GO:0060265//positive regulation of respiratory burst involved in inflammatory response;GO:0044130//negative regulation of growth of symbiont in host;GO:0015920//lipopolysaccharide transport;GO:0033036//macromolecule localization;GO:0032722//positive regulation of chemokine production;GO:0034145//positive regulation of toll-like receptor 4 signaling pathway","K05399//lipopolysaccharide-binding protein","NP_004130.2//lipopolysaccharide-binding protein precursor [Homo sapiens]",4]
[26052,4505,0.27,0.41,0.602664502454615,0.639211267489031,"*",0.48335,"DNM3","GO:0070062//extracellular exosome;GO:0030424//axon;GO:0001917//photoreceptor inner segment;GO:0005874//microtubule;GO:0014069//postsynaptic density;GO:0048471//perinuclear region of cytoplasm;GO:0044327//dendritic spine head;GO:0098844//postsynaptic endocytic zone membrane;GO:0005794//Golgi apparatus;GO:0005739//mitochondrion;GO:0043197//dendritic spine;GO:0031966//mitochondrial membrane;GO:0045202//synapse;GO:0043083//synaptic cleft","GO:0050998//nitric-oxide synthase binding;GO:0031798//type 1 metabotropic glutamate receptor binding;GO:0042802//identical protein binding;GO:0031802//type 5 metabotropic glutamate receptor binding;GO:0005525//GTP binding;GO:0008017//microtubule binding;GO:0003924//GTPase activity","GO:0051491//positive regulation of filopodium assembly;GO:0046847//filopodium assembly;GO:0016185//synaptic vesicle budding from presynaptic endocytic zone membrane;GO:0007416//synapse assembly;GO:0003374//dynamin family protein polymerization involved in mitochondrial fission;GO:0061025//membrane fusion;GO:0006897//endocytosis;GO:0061002//negative regulation of dendritic spine morphogenesis;GO:0098884//postsynaptic neurotransmitter receptor internalization;GO:0000266//mitochondrial fission","K01528//dynamin GTPase [EC:3.6.5.5]","XP_010369589.1//PREDICTED: dynamin-3 isoform X1 [Rhinopithecus roxellana];NP_001337133.1//dynamin-3 isoform d [Homo sapiens];NP_001337134.1//dynamin-3 isoform e [Homo sapiens];NP_001337135.1//dynamin-3 isoform f [Homo sapiens];NP_056384.2//dynamin-3 isoform a [Homo sapiens];XP_018882231.1//PREDICTED: dynamin-3 isoform X6 [Gorilla gorilla gorilla]","4;1//3;2//1"]
[94032,1360,3.11,4.72,0.601872279231239,0.043049316263372,"*",0.01788646,"CAMK2N2","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005813//centrosome","GO:0004860//protein kinase inhibitor activity;GO:0016301//kinase activity;GO:0008427//calcium-dependent protein kinase inhibitor activity;GO:0019901//protein kinase binding","GO:0048167//regulation of synaptic plasticity","K00894//ethanolamine kinase [EC:2.7.1.82];K19475//WAS/WASL-interacting protein;K13171//serine/arginine repetitive matrix protein 1","XP_016284939.1//PREDICTED: calcium/calmodulin-dependent protein kinase II inhibitor 2 [Monodelphis domestica]","2//1"]
[147798,2477,0.87,1.32,0.601450623509725,0.172653231392405,"*",0.0896556,"TMC4","GO:0070062//extracellular exosome;GO:0016021//integral component of membrane","NA","GO:0006811//ion transport","K21988//transmembrane channel-like protein","NP_653287.2//transmembrane channel-like protein 4 isoform 2 [Homo sapiens];NP_001138775.2//transmembrane channel-like protein 4 isoform 1 [Homo sapiens]","3//A2MP1;2//1"]
[25900,2707,0.29,0.44,0.601450623509725,0.475850106306803,"*",0.324492,"IFFO1","GO:0005882//intermediate filament","GO:0005198//structural molecule activity","NA","K07605//type II keratin, basic;K07607//peripherin;K07608//internexin neuronal intermediate filament protein, alpha;K07606//vimentin","NP_001317254.1//intermediate filament family orphan 1 isoform 8 [Homo sapiens];NP_542768.2//intermediate filament family orphan 1 isoform 2 [Homo sapiens];NP_001180386.1//intermediate filament family orphan 1 isoform 5 [Homo sapiens];NP_001034759.1//intermediate filament family orphan 1 isoform 4 [Homo sapiens];NP_001317253.1//intermediate filament family orphan 1 isoform 7 [Homo sapiens]","4;1//3;2//1"]
[90187,3827,0.89,1.35,0.601082166084433,0.0754236426853147,"*",0.0337598,"EMILIN3","GO:0031012//extracellular matrix;GO:0005737//cytoplasm;GO:0005578//proteinaceous extracellular matrix","NA","NA","K16628//collagen, type VII, alpha","EAW75984.1//elastin microfibril interfacer 3, isoform CRA_b [Homo sapiens]","1//3"]
[730005,3394,0.62,0.94,0.600392541290762,0.156816184013689,"*",0.0803224,"SEC14L6","GO:0005622//intracellular;GO:0016021//integral component of membrane","GO:0005215//transporter activity","NA","K01019//galactosylceramide sulfotransferase [EC:2.8.2.11];K17985//activating molecule in BECN1-regulated autophagy protein 1;K17981//mitochondrial fission process protein 1","XP_015005508.1//PREDICTED: LOW QUALITY PROTEIN: putative SEC14-like protein 6 [Macaca mulatta];XP_016884422.1//PREDICTED: putative SEC14-like protein 6 isoform X6 [Homo sapiens]","1//3;3//A2MP1"]
[9976,2052,0.31,0.47,0.600392541290762,0.534673462342912,"*",0.380872,"CLEC2B","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0030246//carbohydrate binding;GO:0042802//identical protein binding","GO:0050776//regulation of immune response","K10071//C-type lectin domain family 2 member B","NP_005118.2//C-type lectin domain family 2 member B [Homo sapiens]","2//1"]
[4713,573,81.61,123.73,0.600377496174123,{"v":2.22404697224425e-13,"d":"2.22E-13"},"*",{"v":1.75568e-14,"d":"1.76E-14"},"NDUFB7","GO:0005747//mitochondrial respiratory chain complex I;GO:0005758//mitochondrial intermembrane space;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0008137//NADH dehydrogenase (ubiquinone) activity","GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0006120//mitochondrial electron transport, NADH to ubiquinone","K03963//NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 7","NP_004137.2//NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 [Homo sapiens]",5]
[91544,1598,9.03,13.69,0.600324553777042,{"v":7.04764339181287e-05,"d":"7.05E-05"},"*",{"v":1.58433e-05,"d":"1.58E-05"},"UBXN11","GO:0005856//cytoskeleton;GO:0005737//cytoplasm","GO:0043130//ubiquitin binding","GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process","K10592//E3 ubiquitin-protein ligase HUWE1 [EC:2.3.2.26]","NP_892120.2//UBX domain-containing protein 11 isoform 2 [Homo sapiens];NP_663320.2//UBX domain-containing protein 11 isoform 1 [Homo sapiens];NP_001070730.1//UBX domain-containing protein 11 isoform 3 [Homo sapiens]","1//3;2//1"]
[64773,1942,32.38,49.07,0.599738285765661,{"v":3.89166349378531e-18,"d":"3.89E-18"},"*",{"v":2.15608E-19,"d":"2.16E-19"},"PCED1A","NA","NA","NA","K05748//WAS protein family, member 2;K02184//formin 2","NP_073597.2//PC-esterase domain-containing protein 1A isoform 1 [Homo sapiens];NP_001258097.1//PC-esterase domain-containing protein 1A isoform 2 [Homo sapiens]","4;1//3"]
[375791,1314,0.99,1.5,0.599462070416271,0.344500432644628,"*",0.208762,"CYSRT1","GO:0070062//extracellular exosome","NA","NA","K13909//mucin-7;K21125//mucin-5AC","NP_945352.3//cysteine-rich tail protein 1 [Homo sapiens]","3//A2MP1"]
[11117,3959,0.66,1,0.599462070416271,0.126883428644962,"*",0.061726,"EMILIN1","NA","NA","NA","K16628//collagen, type VII, alpha","XP_003941621.1//PREDICTED: EMILIN-1 [Saimiri boliviensis boliviensis]","3//A2MP1"]
[6775,2827,4.49,6.8,0.598819301396555,1.40938728443272E-4,"*",{"v":3.34392e-05,"d":"3.34E-05"},"STAT4","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0042802//identical protein binding;GO:0004871//signal transducer activity;GO:0003700//DNA binding transcription factor activity","GO:0007259//JAK-STAT cascade;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0019221//cytokine-mediated signaling pathway;GO:0006351//transcription, DNA-templated;GO:0035722//interleukin-12-mediated signaling pathway","K11222//signal transducer and activator of transcription 4","XP_016805721.1//PREDICTED: signal transducer and activator of transcription 4 isoform X3 [Pan troglodytes];XP_008948871.1//PREDICTED: signal transducer and activator of transcription 4 isoform X1 [Pan paniscus]","1//3;3//A2MP1"]
[246329,1601,0.35,0.53,0.598637437618233,0.634211044676964,"*",0.4781,"STAC3","GO:0005654//nucleoplasm;GO:0005829//cytosol","GO:0046872//metal ion binding;GO:0042802//identical protein binding","GO:0035556//intracellular signal transduction;GO:0048741//skeletal muscle fiber development;GO:0003009//skeletal muscle contraction;GO:0007274//neuromuscular synaptic transmission","K04705//signal transducing adaptor molecule;K07366//GRB2-related adaptor protein 2","NP_001273185.1//SH3 and cysteine-rich domain-containing protein 3 isoform b [Homo sapiens];NP_659501.1//SH3 and cysteine-rich domain-containing protein 3 isoform a [Homo sapiens]","1//3;2//1"]
[10455,1418,24.97,37.8,0.598190413180223,{"v":8.50365055899054e-11,"d":"8.50E-11"},"*",{"v":8.43764E-12,"d":"8.44E-12"},"ECI2","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005654//nucleoplasm;GO:0005782//peroxisomal matrix;GO:0005777//peroxisome;GO:0005739//mitochondrion","GO:0005102//receptor binding;GO:0000062//fatty-acyl-CoA binding;GO:0004165//dodecenoyl-CoA delta-isomerase activity","GO:0033540//fatty acid beta-oxidation using acyl-CoA oxidase;GO:0009062//fatty acid catabolic process","K13239//peroxisomal 3,2-trans-enoyl-CoA isomerase [EC:5.3.3.8]","NP_996667.2//enoyl-CoA delta isomerase 2, mitochondrial isoform 2 [Homo sapiens]","1//3;2//1"]
[5549,5827,0.8,1.21,0.596935142387232,0.0331499104458001,"*",0.01326702,"PRELP","GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:1903561//extracellular vesicle;GO:0005578//proteinaceous extracellular matrix;GO:0005796//Golgi lumen;GO:0005576//extracellular region;GO:0043202//lysosomal lumen","GO:0005201//extracellular matrix structural constituent;GO:0008201//heparin binding","GO:0018146//keratan sulfate biosynthetic process;GO:0042340//keratan sulfate catabolic process;GO:0007569//cell aging;GO:0001501//skeletal system development","K08125//proline arginine-rich end leucine-rich repeat protein","NP_002716.1//prolargin precursor [Homo sapiens]","1//3;3//A2MP1"]
[4929,3546,1.23,1.86,0.596644305768792,0.040523372837407,"*",0.01671012,"NR4A2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016607//nuclear speck;GO:0005737//cytoplasm","GO:0003707//steroid hormone receptor activity;GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0035259//glucocorticoid receptor binding;GO:0042803//protein homodimerization activity;GO:0004879//nuclear receptor activity;GO:0046965//retinoid X receptor binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0008270//zinc ion binding;GO:0008013//beta-catenin binding","GO:0071376//cellular response to corticotropin-releasing hormone stimulus;GO:0008344//adult locomotory behavior;GO:0042053//regulation of dopamine metabolic process;GO:0042416//dopamine biosynthetic process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0009791//post-embryonic development;GO:0043085//positive regulation of catalytic activity;GO:2001234//negative regulation of apoptotic signaling pathway;GO:0031668//cellular response to extracellular stimulus;GO:0051866//general adaptation syndrome;GO:1904948//midbrain dopaminergic neuron differentiation;GO:0007165//signal transduction;GO:0043524//negative regulation of neuron apoptotic process;GO:0006351//transcription, DNA-templated;GO:0071542//dopaminergic neuron differentiation;GO:0021986//habenula development;GO:0001666//response to hypoxia;GO:0001975//response to amphetamine;GO:0060070//canonical Wnt signaling pathway;GO:0001764//neuron migration;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045444//fat cell differentiation;GO:0034599//cellular response to oxidative stress;GO:0021952//central nervous system projection neuron axonogenesis;GO:0043576//regulation of respiratory gaseous exchange;GO:0042551//neuron maturation;GO:0006367//transcription initiation from RNA polymerase II promoter","K08558//nuclear receptor subfamily 4 group A member 2","NP_006177.1//nuclear receptor subfamily 4 group A member 2 [Homo sapiens]","3//A2MP1"]
[131601,3817,21.86,33.04,0.595920285747541,{"v":1.49535103817863e-24,"d":"1.50E-24"},"*",{"v":5.34522e-26,"d":"5.35E-26"},"TPRA1","GO:0016021//integral component of membrane","GO:0004930//G-protein coupled receptor activity","GO:0040016//embryonic cleavage;GO:1901991//negative regulation of mitotic cell cycle phase transition;GO:0006629//lipid metabolic process;GO:0007568//aging","NA","NP_001339936.1//transmembrane protein adipocyte-associated 1 isoform 4 [Homo sapiens];EAW79340.1//G protein-coupled receptor 175, isoform CRA_a [Homo sapiens];NP_001339935.1//transmembrane protein adipocyte-associated 1 isoform 3 [Homo sapiens];EAW79341.1//G protein-coupled receptor 175, isoform CRA_b, partial [Homo sapiens]","1//3;3//A2MP1"]
[27,11776,3.5,5.29,0.595912800281697,{"v":7.89988667978804e-13,"d":"7.90E-13"},"*",{"v":6.53296e-14,"d":"6.53E-14"},"ABL2","GO:0005623//cell;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0005829//cytosol;GO:0015629//actin cytoskeleton","GO:0000287//magnesium ion binding;GO:0051015//actin filament binding;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005524//ATP binding;GO:0005102//receptor binding;GO:0003785//actin monomer binding;GO:0004713//protein tyrosine kinase activity;GO:0001784//phosphotyrosine residue binding;GO:0004672//protein kinase activity;GO:0030145//manganese ion binding","GO:0038083//peptidyl-tyrosine autophosphorylation;GO:0030100//regulation of endocytosis;GO:0042127//regulation of cell proliferation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0051353//positive regulation of oxidoreductase activity;GO:0010506//regulation of autophagy;GO:0030155//regulation of cell adhesion;GO:0045087//innate immune response;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030154//cell differentiation;GO:0007165//signal transduction;GO:0010976//positive regulation of neuron projection development;GO:2000145//regulation of cell motility;GO:0010863//positive regulation of phospholipase C activity;GO:2000249//regulation of actin cytoskeleton reorganization;GO:0071300//cellular response to retinoic acid;GO:0007155//cell adhesion;GO:0006464//cellular protein modification process;GO:0007204//positive regulation of cytosolic calcium ion concentration","K08887//abelson tyrosine-protein kinase 2 [EC:2.7.10.2]","NP_001161710.1//Abelson tyrosine-protein kinase 2 isoform h [Homo sapiens];NP_009298.1//Abelson tyrosine-protein kinase 2 isoform b [Homo sapiens];NP_001161709.1//Abelson tyrosine-protein kinase 2 isoform g [Homo sapiens];NP_001129473.1//Abelson tyrosine-protein kinase 2 isoform e [Homo sapiens];NP_005149.4//Abelson tyrosine-protein kinase 2 isoform c [Homo sapiens];CAD98092.1//hypothetical protein, partial [Homo sapiens];NP_001161708.1//Abelson tyrosine-protein kinase 2 isoform f [Homo sapiens]","4;1//3;3//A2MP1;2//1"]
[57169,7371,9.86,14.9,0.595652778971613,{"v":1.06254497267442E-21,"d":"1.06E-21"},"*",{"v":4.57638e-23,"d":"4.58E-23"},"ZNFX1","GO:0005634//nucleus","GO:0003723//RNA binding;GO:0008270//zinc ion binding;GO:0003700//DNA binding transcription factor activity","NA","K14326//regulator of nonsense transcripts 1 [EC:3.6.4.-]","NP_066363.1//NFX1-type zinc finger-containing protein 1 [Homo sapiens]","2//1"]
[151963,3388,1.88,2.84,0.595158267827045,0.0104825672655266,"*",3.64534E-3,"MB21D2","NA","GO:0032403//protein complex binding;GO:0045296//cadherin binding","NA","K04358//fibroblast growth factor","XP_021083798.1//protein MB21D2 [Mesocricetus auratus]","3//A2MP1"]
[147968,3129,27.77,41.95,0.59514363350834,{"v":1.9281956603352E-25,"d":"1.93E-25"},"*",{"v":6.48204e-27,"d":"6.48E-27"},"CAPN12","GO:0005737//cytoplasm","GO:0004198//calcium-dependent cysteine-type endopeptidase activity;GO:0005509//calcium ion binding","GO:0006508//proteolysis","K04740//calpain-12 [EC:3.4.22.-]","NP_653292.2//calpain-12 [Homo sapiens]",4]
[5271,3309,2.84,4.29,0.595086717994864,0.00285121076075872,"*",0.00087514,"SERPINB8","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0004867//serine-type endopeptidase inhibitor activity","GO:0090136//epithelial cell-cell adhesion;GO:0010951//negative regulation of endopeptidase activity","K13965//serpin B8","NP_001335296.1//serpin B8 isoform d [Homo sapiens];NP_001335297.1//serpin B8 isoform e [Homo sapiens];NP_001335299.1//serpin B8 isoform f [Homo sapiens];NP_942130.1//serpin B8 isoform a [Homo sapiens]","1//3;3//A2MP1"]
[84808,3089,0.96,1.45,0.594946589293778,0.0850239376323388,"*",0.0387116,"PERM1","GO:0005634//nucleus;GO:0005737//cytoplasm","NA","GO:0014850//response to muscle activity;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K14282//transforming acidic coiled-coil-containing protein 2;K16882//protein piccolo","NP_001278296.1//PGC-1 and ERR-induced regulator in muscle protein 1 isoform 2 [Homo sapiens];NP_001278295.1//PGC-1 and ERR-induced regulator in muscle protein 1 isoform 1 [Homo sapiens]","1//3"]
[124976,3459,0.96,1.45,0.594946589293778,0.087094316807871,"*",0.0398996,"SPNS2","GO:0005765//lysosomal membrane;GO:0016021//integral component of membrane;GO:0031982//vesicle","GO:0046624//sphingolipid transporter activity","GO:0003376//sphingosine-1-phosphate signaling pathway;GO:0060348//bone development;GO:0055085//transmembrane transport;GO:0048535//lymph node development;GO:0002920//regulation of humoral immune response;GO:0043029//T cell homeostasis;GO:0006665//sphingolipid metabolic process;GO:0040011//locomotion;GO:0001782//B cell homeostasis;GO:0072676//lymphocyte migration;GO:0048073//regulation of eye pigmentation","K20225//capicua transcriptional repressor;K14156//choline/ethanolamine kinase [EC:2.7.1.32 2.7.1.82];K19720//collagen, type III, alpha","AAH11467.1//Spns2 protein, partial [Mus musculus]","2//1"]
[7262,937,58.56,88.44,0.594783471532183,{"v":8.84783795066414e-16,"d":"8.85E-16"},"*",{"v":5.838e-17,"d":"5.84E-17"},"PHLDA2","GO:0016020//membrane;GO:0005737//cytoplasm","NA","GO:0010468//regulation of gene expression;GO:0001890//placenta development;GO:1903547//regulation of growth hormone activity;GO:0070873//regulation of glycogen metabolic process;GO:0060721//regulation of spongiotrophoblast cell proliferation;GO:0006915//apoptotic process;GO:0009887//animal organ morphogenesis;GO:0030334//regulation of cell migration","K03006//DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6];K17298//mucin-13","NP_003302.1//pleckstrin homology-like domain family A member 2 [Homo sapiens]","3//A2MP1"]
[4783,2102,6.49,9.8,0.594563271003432,1.21739415046854E-4,"*",{"v":2.84648e-05,"d":"2.85E-05"},"NFIL3","GO:0005634//nucleus","GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007623//circadian rhythm;GO:0006355//regulation of transcription, DNA-templated;GO:0006955//immune response;GO:0071353//cellular response to interleukin-4;GO:0010628//positive regulation of gene expression;GO:0006366//transcription from RNA polymerase II promoter","K09059//nuclear factor, interleukin 3 regulated","NP_005375.2//nuclear factor interleukin-3-regulated protein [Homo sapiens]","1//3;2//1"]
[4987,3331,0.61,0.92,0.592824618494127,0.239095377390527,"*",0.1339916,"OPRL1","GO:0005887//integral component of plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0043005//neuron projection","GO:0008022//protein C-terminus binding;GO:0042923//neuropeptide binding;GO:0001626//nociceptin receptor activity;GO:0004930//G-protein coupled receptor activity","GO:0007600//sensory perception;GO:0044849//estrous cycle;GO:0045776//negative regulation of blood pressure;GO:0032355//response to estradiol;GO:0019233//sensory perception of pain;GO:0001934//positive regulation of protein phosphorylation;GO:0007218//neuropeptide signaling pathway;GO:0060454//positive regulation of gastric acid secretion;GO:0030818//negative regulation of cAMP biosynthetic process;GO:1904059//regulation of locomotor rhythm;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:1904058//positive regulation of sensory perception of pain;GO:0042755//eating behavior;GO:1901386//negative regulation of voltage-gated calcium channel activity;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007268//chemical synaptic transmission;GO:0035810//positive regulation of urine volume","K04216//nociceptin receptor","NP_001305782.1//nociceptin receptor isoform 1x [Homo sapiens];NP_001305784.1//nociceptin receptor isoform 3 [Homo sapiens]","1//3;3//A2MP1;5"]
[6282,595,1037.94,1563.49,0.591046943382107,{"v":2.99577848181818e-163,"d":"3.00E-163"},"*",{"v":8.2518e-166,"d":"8.25E-166"},"S100A11","GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0001726//ruffle;GO:0005913//cell-cell adherens junction;GO:0005576//extracellular region","GO:0098641//cadherin binding involved in cell-cell adhesion;GO:0044548//S100 protein binding;GO:0005509//calcium ion binding;GO:0048306//calcium-dependent protein binding;GO:0042803//protein homodimerization activity","GO:0007165//signal transduction;GO:0042127//regulation of cell proliferation;GO:0043312//neutrophil degranulation;GO:0008156//negative regulation of DNA replication;GO:0008285//negative regulation of cell proliferation","K17274//calpactin-1 light chain","XP_010340417.1//PREDICTED: uncharacterized protein LOC101045489 [Saimiri boliviensis boliviensis]","1//3"]
[129303,1556,9.25,13.93,0.590669987197578,{"v":7.84897651837524e-05,"d":"7.85E-05"},"*",{"v":1.77823e-05,"d":"1.78E-05"},"TMEM150A","NA","NA","NA","K21846//transmembrane protein 150","XP_007120732.1//PREDICTED: transmembrane protein 150A [Physeter catodon]","2//1"]
[268,1883,10.12,15.24,0.590653612799012,{"v":3.89436432115782E-6,"d":"3.89E-06"},"*",{"v":7.0749e-07,"d":"7.07E-07"},"AMH","GO:0005615//extracellular space;GO:0005576//extracellular region","GO:0008083//growth factor activity;GO:0005102//receptor binding;GO:0005160//transforming growth factor beta receptor binding;GO:0005179//hormone activity","GO:0014070//response to organic cyclic compound;GO:0042493//response to drug;GO:0001655//urogenital system development;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0007267//cell-cell signaling;GO:0007530//sex determination;GO:0030509//BMP signaling pathway;GO:0010628//positive regulation of gene expression;GO:0007568//aging;GO:0008406//gonad development;GO:0007548//sex differentiation;GO:2000355//negative regulation of ovarian follicle development;GO:0001880//Mullerian duct regression;GO:0007506//gonadal mesoderm development;GO:0001546//preantral ovarian follicle growth","K04665//anti-mullerian hormone","NP_000470.2//muellerian-inhibiting factor preproprotein [Homo sapiens]",4]
[60490,2268,5.35,8.04,0.587656609890419,0.000376611778156997,"*",{"v":9.6711e-05,"d":"9.67E-05"},"PPCDC","GO:0005829//cytosol","GO:0042802//identical protein binding;GO:0003824//catalytic activity;GO:0004633//phosphopantothenoylcysteine decarboxylase activity","GO:0009108//coenzyme biosynthetic process;GO:0015937//coenzyme A biosynthetic process","K01598//phosphopantothenoylcysteine decarboxylase [EC:4.1.1.36]","XP_011946188.1//PREDICTED: phosphopantothenoylcysteine decarboxylase isoform X3 [Cercocebus atys];NP_068595.3//phosphopantothenoylcysteine decarboxylase isoform a [Homo sapiens];XP_011946186.1//PREDICTED: phosphopantothenoylcysteine decarboxylase isoform X1 [Cercocebus atys]","4;1//3"]
[718,5148,5.9,8.86,0.586591744305815,{"v":2.98261133087071E-9,"d":"2.98E-09"},"*",{"v":3.53828e-10,"d":"3.54E-10"},"C3","GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome;GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0072562//blood microparticle;GO:0035578//azurophil granule lumen;GO:0043234//protein complex;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0004252//serine-type endopeptidase activity;GO:0005102//receptor binding;GO:0004866//endopeptidase inhibitor activity;GO:0031715//C5L2 anaphylatoxin chemotactic receptor binding","GO:0043687//post-translational protein modification;GO:0030449//regulation of complement activation;GO:0006911//phagocytosis, engulfment;GO:0010575//positive regulation of vascular endothelial growth factor production;GO:0097242//amyloid-beta clearance;GO:0010884//positive regulation of lipid storage;GO:0010828//positive regulation of glucose transport;GO:0050766//positive regulation of phagocytosis;GO:0044267//cellular protein metabolic process;GO:0001970//positive regulation of activation of membrane attack complex;GO:2000427//positive regulation of apoptotic cell clearance;GO:0006631//fatty acid metabolic process;GO:0001934//positive regulation of protein phosphorylation;GO:0043312//neutrophil degranulation;GO:0045766//positive regulation of angiogenesis;GO:0050776//regulation of immune response;GO:0007186//G-protein coupled receptor signaling pathway;GO:0006956//complement activation;GO:0007165//signal transduction;GO:0006957//complement activation, alternative pathway;GO:0006954//inflammatory response;GO:0006958//complement activation, classical pathway;GO:0045745//positive regulation of G-protein coupled receptor protein signaling pathway;GO:0001798//positive regulation of type IIa hypersensitivity;GO:0010866//regulation of triglyceride biosynthetic process;GO:0006955//immune response","K03990//complement component 3","NP_000055.2//complement C3 preproprotein [Homo sapiens]","3//A2MP1"]
[102800317,2997,1.44,2.16,0.584962500721156,0.0468520303565568,"*",0.01966002,"LOC400927-CSNK1E","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0030426//growth cone;GO:0030529//intracellular ribonucleoprotein complex;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0043025//neuronal cell body","GO:0003723//RNA binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity","GO:0030178//negative regulation of Wnt signaling pathway;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:1990090//cellular response to nerve growth factor stimulus;GO:0097711//ciliary basal body-plasma membrane docking;GO:2000052//positive regulation of non-canonical Wnt signaling pathway;GO:0032091//negative regulation of protein binding;GO:1902004//positive regulation of amyloid-beta formation;GO:0006897//endocytosis;GO:0032922//circadian regulation of gene expression;GO:0007165//signal transduction;GO:0006281//DNA repair;GO:1905426//positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation;GO:0006468//protein phosphorylation;GO:0006364//rRNA processing;GO:0008360//regulation of cell shape;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0042752//regulation of circadian rhythm;GO:0010389//regulation of G2/M transition of mitotic cell cycle;GO:0018105//peptidyl-serine phosphorylation;GO:0034613//cellular protein localization;GO:0016055//Wnt signaling pathway;GO:0000086//G2/M transition of mitotic cell cycle;GO:0048512//circadian behavior;GO:1903827//regulation of cellular protein localization","K08960//casein kinase 1, epsilon [EC:2.7.11.1]","NP_001885.1//casein kinase I isoform epsilon [Homo sapiens]","1//3"]
[8399,924,0.18,0.27,0.584962500721156,0.78091745073435,"*",0.685686,"PLA2G10","GO:0005615//extracellular space;GO:0005576//extracellular region","GO:0004620//phospholipase activity;GO:0102567//phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine);GO:0005509//calcium ion binding;GO:0102568//phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine);GO:0004623//phospholipase A2 activity","GO:0010744//positive regulation of macrophage derived foam cell differentiation;GO:0016042//lipid catabolic process;GO:0019369//arachidonic acid metabolic process;GO:0032270//positive regulation of cellular protein metabolic process;GO:0043433//negative regulation of DNA binding transcription factor activity;GO:0043030//regulation of macrophage activation;GO:0032308//positive regulation of prostaglandin secretion;GO:0010884//positive regulation of lipid storage;GO:0006654//phosphatidic acid biosynthetic process;GO:0036152//phosphatidylethanolamine acyl-chain remodeling;GO:0050482//arachidonic acid secretion;GO:0051977//lysophospholipid transport;GO:0036151//phosphatidylcholine acyl-chain remodeling;GO:0042632//cholesterol homeostasis;GO:0007411//axon guidance;GO:0036150//phosphatidylserine acyl-chain remodeling;GO:0036149//phosphatidylinositol acyl-chain remodeling;GO:0090370//negative regulation of cholesterol efflux;GO:1990830//cellular response to leukemia inhibitory factor;GO:0006644//phospholipid metabolic process;GO:0036148//phosphatidylglycerol acyl-chain remodeling;GO:0090238//positive regulation of arachidonic acid secretion","K01047//secretory phospholipase A2 [EC:3.1.1.4]","NP_003552.1//group 10 secretory phospholipase A2 preproprotein [Homo sapiens]","2//1"]
[100129583,1627,0.06,0.09,0.584962500721156,1.01076013890121,"*",0.998548,"FAM47E","GO:0005737//cytoplasm","NA","NA","K00522//ferritin heavy chain [EC:1.16.3.2];K22267//starch-binding domain-containing protein 1","NP_001229865.1//protein FAM47E isoform b [Homo sapiens];NP_001130042.1//protein FAM47E isoform a [Homo sapiens]","1//3;2//1"]
[50859,1544,0.16,0.24,0.584962500721156,0.831302844401357,"*",0.751524,"SPOCK3","GO:0031012//extracellular matrix;GO:0005615//extracellular space;GO:0005578//proteinaceous extracellular matrix","GO:0008191//metalloendopeptidase inhibitor activity;GO:0005509//calcium ion binding;GO:0005539//glycosaminoglycan binding","GO:0019800//peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan;GO:0007165//signal transduction;GO:0010951//negative regulation of endopeptidase activity;GO:2000146//negative regulation of cell motility","K08136//sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican)","NP_001191287.1//testican-3 isoform 9 precursor [Homo sapiens];XP_011815041.1//PREDICTED: testican-3 isoform X4 [Colobus angolensis palliatus];XP_011815044.1//PREDICTED: testican-3 isoform X7 [Colobus angolensis palliatus];XP_021554515.1//testican-3 isoform X4 [Neomonachus schauinslandi];NP_058646.2//testican-3 isoform 2 precursor [Homo sapiens];XP_016863746.1//PREDICTED: testican-3 isoform X1 [Homo sapiens]","1//3;2//1"]
[43,2170,0.5,0.75,0.584962500721156,0.440210757390896,"*",0.29363,"ACHE","GO:0016020//membrane;GO:0005605//basal lamina;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0031594//neuromuscular junction;GO:0030054//cell junction;GO:0031225//anchored component of membrane;GO:0048471//perinuclear region of cytoplasm;GO:0009986//cell surface;GO:0005794//Golgi apparatus;GO:0005576//extracellular region;GO:0043083//synaptic cleft;GO:0045202//synapse;GO:0005886//plasma membrane","GO:0001540//amyloid-beta binding;GO:0017171//serine hydrolase activity;GO:0043621//protein self-association;GO:0043236//laminin binding;GO:0042803//protein homodimerization activity;GO:0004104//cholinesterase activity;GO:0042166//acetylcholine binding;GO:0005518//collagen binding;GO:0016787//hydrolase activity;GO:0003990//acetylcholinesterase activity","GO:0060041//retina development in camera-type eye;GO:0007399//nervous system development;GO:0031623//receptor internalization;GO:0045212//neurotransmitter receptor biosynthetic process;GO:0006260//DNA replication;GO:0007416//synapse assembly;GO:0008283//cell proliferation;GO:0042982//amyloid precursor protein metabolic process;GO:0001507//acetylcholine catabolic process in synaptic cleft;GO:0009611//response to wounding;GO:0042136//neurotransmitter biosynthetic process;GO:0007517//muscle organ development;GO:0032223//negative regulation of synaptic transmission, cholinergic;GO:0051262//protein tetramerization;GO:0006581//acetylcholine catabolic process;GO:0050714//positive regulation of protein secretion;GO:0007155//cell adhesion;GO:0006656//phosphatidylcholine biosynthetic process;GO:0001919//regulation of receptor recycling;GO:0002076//osteoblast development","K01049//acetylcholinesterase [EC:3.1.1.7]","XP_016867709.1//PREDICTED: acetylcholinesterase isoform X4 [Homo sapiens];XP_018886475.1//PREDICTED: acetylcholinesterase isoform X2 [Gorilla gorilla gorilla];XP_009200999.1//acetylcholinesterase isoform X1 [Papio anubis];XP_016813400.1//PREDICTED: acetylcholinesterase isoform X4 [Pan troglodytes]","4;1//3"]
[56121,2891,0.08,0.12,0.584962500721156,0.609349329390893,"*",0.451538,"PCDHB15","GO:0005887//integral component of plasma membrane","GO:0005509//calcium ion binding","GO:0007416//synapse assembly;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007268//chemical synaptic transmission","K16494//protocadherin beta","XP_003780466.1//PREDICTED: LOW QUALITY PROTEIN: protocadherin beta-15 [Pongo abelii]","3//A2MP1"]
[122060,1968,0.08,0.12,0.584962500721156,1.01613865417224,"*",0.997882,"SLAIN1","GO:0005856//cytoskeleton;GO:0005737//cytoplasm","NA","NA","K16580//SLAIN motif-containing protein 1/2","NP_001035243.2//SLAIN motif-containing protein 1 isoform A precursor [Homo sapiens];XP_015495887.1//PREDICTED: SLAIN motif-containing protein 1 isoform X2 [Parus major];NP_001229797.1//SLAIN motif-containing protein 1 isoform C [Homo sapiens];AAH45177.2//SLAIN1 protein, partial [Homo sapiens];XP_019776699.1//PREDICTED: SLAIN motif-containing protein 1 isoform X2 [Tursiops truncatus]","1//3;3//A2MP1"]
[144195,4368,0.02,0.03,0.584962500721156,1.00858714840341,"*",0.998548,"SLC2A14","GO:0016021//integral component of membrane","GO:0005355//glucose transmembrane transporter activity","NA","K08142//MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 3","XP_005570090.1//PREDICTED: solute carrier family 2, facilitated glucose transporter member 3 [Macaca fascicularis]","1//3;3//A2MP1"]
[163589,2501,0.02,0.03,0.584962500721156,1.00852337835104,"*",0.998548,"TDRD5","GO:0071546//pi-body;GO:0033391//chromatoid body","NA","GO:0043046//DNA methylation involved in gamete generation;GO:0030719//P granule organization;GO:0007286//spermatid development","K18407//tudor domain-containing protein 5","NP_775804.2//tudor domain-containing protein 5 isoform 2 [Homo sapiens];NP_001186014.1//tudor domain-containing protein 5 isoform 1 [Homo sapiens]","1//3;4;2//1"]
[91851,4101,0.04,0.06,0.584962500721156,0.782200111690352,"*",0.685686,"CHRDL1","GO:0005788//endoplasmic reticulum lumen;GO:0005576//extracellular region","NA","GO:0043687//post-translational protein modification;GO:0007399//nervous system development;GO:0030514//negative regulation of BMP signaling pathway;GO:0001654//eye development;GO:0030154//cell differentiation;GO:0048749//compound eye development;GO:0030509//BMP signaling pathway;GO:0001503//ossification;GO:0044267//cellular protein metabolic process","K17280//chordin-like protein 2","XP_012605477.1//chordin-like protein 1 isoform X1 [Microcebus murinus];XP_008064999.1//chordin-like protein 1 isoform X4 [Carlito syrichta];NP_660277.2//chordin-like protein 1 isoform 3 precursor [Homo sapiens];XP_012605485.1//chordin-like protein 1 isoform X2 [Microcebus murinus]","1//3;3//A2MP1;2//1"]
[2563,1942,0.08,0.12,0.584962500721156,0.782144256212511,"*",0.685686,"GABRD","GO:0030054//cell junction;GO:0034707//chloride channel complex;GO:1902711//GABA-A receptor complex;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0045202//synapse;GO:0045211//postsynaptic membrane","GO:0005230//extracellular ligand-gated ion channel activity;GO:0004890//GABA-A receptor activity;GO:0005254//chloride channel activity","GO:0006810//transport;GO:0007165//signal transduction;GO:0007268//chemical synaptic transmission","K05184//gamma-aminobutyric acid receptor subunit delta","NP_000806.2//gamma-aminobutyric acid receptor subunit delta precursor [Homo sapiens]",4]
[728116,4019,0.04,0.06,0.584962500721156,0.782088408711175,"*",0.685686,"ZBTB8B","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K10495//zinc finger and BTB domain-containing protein 8","EAX07524.1//hCG1788238, partial [Homo sapiens]","1//3"]
[2676,1980,0.08,0.12,0.584962500721156,0.781976737631184,"*",0.685686,"GFRA3","GO:0009897//external side of plasma membrane;GO:0019898//extrinsic component of membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0031225//anchored component of membrane","GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005102//receptor binding;GO:0008046//axon guidance receptor activity","GO:0007399//nervous system development;GO:0048485//sympathetic nervous system development;GO:0000165//MAPK cascade;GO:0007165//signal transduction;GO:0001764//neuron migration;GO:0007422//peripheral nervous system development;GO:0007411//axon guidance","K19895//GDNF family receptor alpha 1","NP_001487.2//GDNF family receptor alpha-3 preproprotein [Homo sapiens]","3//A2MP1"]
[345462,2644,0.12,0.18,0.584962500721156,0.666015041110518,"*",0.546646,"ZNF879","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_014922199.1//PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 879 [Acinonyx jubatus]","1//3;2//1"]
[441151,4637,0.02,0.03,0.584962500721156,0.734933649524091,"*",0.623548,"TMEM151B","GO:0016021//integral component of membrane","NA","NA","K22020//mucin-19","NP_001131032.1//transmembrane protein 151B [Homo sapiens]","1//3"]
[389170,1976,0.24,0.36,0.584962500721156,0.60876773971679,"*",0.452136,"LEKR1","NA","NA","NA","K20478//golgin subfamily B member 1","XP_011511118.1//PREDICTED: leucine-, glutamate- and lysine-rich protein 1 isoform X11 [Homo sapiens];XP_006713694.1//PREDICTED: leucine-, glutamate- and lysine-rich protein 1 isoform X1 [Homo sapiens]","1//3;2//1"]
[3357,1857,0.26,0.39,0.584962500721156,0.608716431858407,"*",0.452136,"HTR2B","GO:0005887//integral component of plasma membrane;GO:0030054//cell junction;GO:0045202//synapse;GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0043005//neuron projection","GO:0051378//serotonin binding;GO:0004993//G-protein coupled serotonin receptor activity;GO:0001965//G-protein alpha-subunit binding;GO:0008144//drug binding;GO:0030594//neurotransmitter receptor activity;GO:0005096//GTPase activator activity","GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0016310//phosphorylation;GO:0050795//regulation of behavior;GO:0001819//positive regulation of cytokine production;GO:0070371//ERK1 and ERK2 cascade;GO:0071502//cellular response to temperature stimulus;GO:0007610//behavior;GO:0042493//response to drug;GO:0001755//neural crest cell migration;GO:0070528//protein kinase C signaling;GO:0019722//calcium-mediated signaling;GO:0043066//negative regulation of apoptotic process;GO:0003300//cardiac muscle hypertrophy;GO:0006182//cGMP biosynthetic process;GO:0007202//activation of phospholipase C activity;GO:0051209//release of sequestered calcium ion into cytosol;GO:0048598//embryonic morphogenesis;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0051000//positive regulation of nitric-oxide synthase activity;GO:0042310//vasoconstriction;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0051781//positive regulation of cell division;GO:0007210//serotonin receptor signaling pathway;GO:0003007//heart morphogenesis;GO:0001938//positive regulation of endothelial cell proliferation;GO:0006874//cellular calcium ion homeostasis;GO:0007186//G-protein coupled receptor signaling pathway;GO:0043406//positive regulation of MAP kinase activity;GO:0010513//positive regulation of phosphatidylinositol biosynthetic process;GO:0014033//neural crest cell differentiation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0010507//negative regulation of autophagy;GO:0060548//negative regulation of cell death;GO:0014827//intestine smooth muscle contraction;GO:0002031//G-protein coupled receptor internalization;GO:0050715//positive regulation of cytokine secretion;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0008284//positive regulation of cell proliferation","K04157//5-hydroxytryptamine receptor 2","NP_000858.3//5-hydroxytryptamine receptor 2B isoform 1 [Homo sapiens]","1//3;4"]
[3851,2147,0.3,0.45,0.584962500721156,0.534861479384615,"*",0.380872,"KRT4","NA","NA","NA","K07605//type II keratin, basic","XP_017357230.1//PREDICTED: keratin, type II cytoskeletal 4 [Cebus capucinus imitator]","3//A2MP1"]
[57159,1947,0.08,0.12,0.584962500721156,0.781307380269634,"*",0.685686,"TRIM54","GO:0030018//Z disc;GO:0005875//microtubule associated complex;GO:0005874//microtubule","GO:0008270//zinc ion binding;GO:0004871//signal transducer activity;GO:0008017//microtubule binding","GO:0055001//muscle cell development;GO:0070507//regulation of microtubule cytoskeleton organization;GO:0007165//signal transduction;GO:0007275//multicellular organism development;GO:0007026//negative regulation of microtubule depolymerization;GO:0007017//microtubule-based process","K10653//tripartite motif-containing protein 54","NP_912730.2//tripartite motif-containing protein 54 isoform 2 [Homo sapiens];NP_115935.3//tripartite motif-containing protein 54 isoform 1 [Homo sapiens]","3//A2MP1;2//1"]
[93035,19969,0.06,0.09,0.584962500721156,0.384167835298821,"*",0.24064,"PKHD1L1","NA","NA","NA","K19865//fibrocystin","XP_016869458.1//PREDICTED: fibrocystin-L isoform X1 [Homo sapiens]",5]
[345051,3626,0.02,0.03,0.584962500721156,1.00439555141364,"*",0.998548,"REELD1","NA","NA","NA","K02599//Notch 1","NP_001341560.1//reeler domain containing 1 precursor [Homo sapiens]","1//3"]
[79400,2725,0.06,0.09,0.584962500721156,0.780973131122995,"*",0.685686,"NOX5","GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0050661//NADP binding;GO:0020037//heme binding;GO:0005509//calcium ion binding;GO:0050660//flavin adenine dinucleotide binding;GO:0016175//superoxide-generating NADPH oxidase activity;GO:0015252//proton channel activity","GO:0050663//cytokine secretion;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0001525//angiogenesis;GO:0000910//cytokinesis;GO:0055114//oxidation-reduction process;GO:0006915//apoptotic process;GO:0008283//cell proliferation;GO:0034599//cellular response to oxidative stress;GO:0042554//superoxide anion generation;GO:0043012//regulation of fusion of sperm to egg plasma membrane;GO:0010155//regulation of proton transport;GO:0001935//endothelial cell proliferation","K21424//NADPH oxidase 5 [EC:1.6.3.-]","NP_078781.3//NADPH oxidase 5 isoform 1 [Homo sapiens];NP_001171708.1//NADPH oxidase 5 isoform 2 [Homo sapiens];NP_001171709.1//NADPH oxidase 5 isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[64577,2405,0.32,0.48,0.584962500721156,0.453467849688401,"*",0.305198,"ALDH8A1","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0005622//intracellular","GO:0001758//retinal dehydrogenase activity","GO:0042573//retinoic acid metabolic process;GO:0042904//9-cis-retinoic acid biosynthetic process;GO:0042574//retinal metabolic process","K00129//aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5];K07249//retinal dehydrogenase [EC:1.2.1.36];K06564//insulin-like growth factor 2 receptor;K00149//aldehyde dehydrogenase family 9 member A1 [EC:1.2.1.47 1.2.1.3]","NP_072090.1//aldehyde dehydrogenase family 8 member A1 isoform 1 [Homo sapiens];NP_739577.1//aldehyde dehydrogenase family 8 member A1 isoform 2 [Homo sapiens];NP_001180409.1//aldehyde dehydrogenase family 8 member A1 isoform 3 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[145501,2660,0.12,0.18,0.584962500721156,0.665761146996035,"*",0.546646,"ISM2","GO:0005576//extracellular region","NA","NA","K10955//mucin-2","CAD62605.1//unnamed protein product, partial [Homo sapiens];NP_954993.1//isthmin-2 isoform 1 precursor [Homo sapiens]","3//A2MP1;2//1"]
[55259,2012,0.08,0.12,0.584962500721156,0.780583535062714,"*",0.685686,"CASC1","NA","NA","NA","K17580//cancer susceptibility candidate protein 1","NP_001338996.1//protein CASC1 isoform l [Homo sapiens];NP_001338991.1//protein CASC1 isoform g [Homo sapiens];NP_060742.3//protein CASC1 isoform a [Homo sapiens];NP_001076442.1//protein CASC1 isoform b [Homo sapiens];XP_016875054.1//PREDICTED: protein CASC1 isoform X9 [Homo sapiens];NP_001338992.1//protein CASC1 isoform h [Homo sapiens];NP_001191030.1//protein CASC1 isoform e [Homo sapiens];NP_001191031.1//protein CASC1 isoform d [Homo sapiens];NP_001076441.1//protein CASC1 isoform c [Homo sapiens];NP_001338993.1//protein CASC1 isoform i [Homo sapiens]","4;1//3;2//1"]
[23440,2702,0.06,0.09,0.584962500721156,0.780527910211644,"*",0.685686,"OTP","NA","NA","NA","K09452//homeobox protein aristaless-related","XP_004058722.2//PREDICTED: homeobox protein orthopedia [Gorilla gorilla gorilla]","2//1"]
[55885,3838,0.04,0.06,0.584962500721156,0.78047229328773,"*",0.685686,"LMO3","GO:0005737//cytoplasm","GO:0046872//metal ion binding","GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0006355//regulation of transcription, DNA-templated;GO:0045600//positive regulation of fat cell differentiation;GO:0006351//transcription, DNA-templated;GO:0035360//positive regulation of peroxisome proliferator activated receptor signaling pathway;GO:2000324//positive regulation of glucocorticoid receptor signaling pathway","K15612//rhombotin-2","XP_007942636.1//PREDICTED: LIM domain only protein 3 isoform X1 [Orycteropus afer afer];NP_001230541.1//LIM domain only protein 3 isoform 3 [Homo sapiens];XP_005664099.1//LIM domain only protein 3 isoform X1 [Sus scrofa];XP_020946522.1//LIM domain only protein 3 isoform X2 [Sus scrofa];XP_008967811.1//PREDICTED: LIM domain only protein 3 isoform X1 [Pan paniscus];XP_005570312.1//PREDICTED: LIM domain only protein 3 isoform X1 [Macaca fascicularis]","4;1//3;2//1"]
[83733,2089,0.08,0.12,0.584962500721156,0.780194327516205,"*",0.685686,"SLC25A18","NA","NA","NA","K15107//solute carrier family 25 (mitochondrial glutamate transporter), member 18/22","XP_011544451.1//PREDICTED: mitochondrial glutamate carrier 2 isoform X1 [Homo sapiens]","1//3;2//1"]
[55057,5245,0.06,0.09,0.584962500721156,0.665558171036585,"*",0.546646,"CRYBG2","NA","GO:0030246//carbohydrate binding","NA","K16810//TBCC domain-containing protein 1;K01886//glutaminyl-tRNA synthetase [EC:6.1.1.18]","XP_011539975.1//PREDICTED: absent in melanoma 1-like protein isoform X3 [Homo sapiens]","3//A2MP1"]
[169436,2794,0.06,0.09,0.584962500721156,0.780083196638416,"*",0.685686,"STKLD1","NA","GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding","NA","K17546//probable inactive protein kinase-like protein SgK071","NP_714921.4//serine/threonine kinase-like domain-containing protein STKLD1 [Homo sapiens]",4]
[8352,459,0.38,0.57,0.584962500721156,0.782703170215807,"*",0.685686,"HIST1H3C","NA","NA","NA","K11253//histone H3","XP_012669845.1//PREDICTED: uncharacterized protein LOC105888650 [Clupea harengus]","2//1"]
[2861,5614,0.1,0.15,0.584962500721156,0.512128993086109,"*",0.357054,"GPR37","GO:0005783//endoplasmic reticulum;GO:0005887//integral component of plasma membrane;GO:0000151//ubiquitin ligase complex;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0043235//receptor complex","GO:0008528//G-protein coupled peptide receptor activity;GO:0036505//prosaposin receptor activity;GO:0031072//heat shock protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0042277//peptide binding;GO:0030544//Hsp70 protein binding;GO:0004930//G-protein coupled receptor activity","GO:0045964//positive regulation of dopamine metabolic process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:1903206//negative regulation of hydrogen peroxide-induced cell death;GO:0043410//positive regulation of MAPK cascade;GO:0031987//locomotion involved in locomotory behavior;GO:0042416//dopamine biosynthetic process","K04243//G protein-coupled receptor 37 (endothelin receptor type B-like)","NP_005293.1//prosaposin receptor GPR37 precursor [Homo sapiens]",4]
[619373,1663,0.1,0.15,0.584962500721156,0.781809290792291,"*",0.685686,"MBOAT4","GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005789//endoplasmic reticulum membrane","GO:0016412//serine O-acyltransferase activity;GO:0008374//O-acyltransferase activity","GO:0018191//peptidyl-serine octanoylation","K13517//lysophospholipid acyltransferase 1/2 [EC:2.3.1.51 2.3.1.-]","NP_001094386.1//ghrelin O-acyltransferase [Homo sapiens]","1//3"]
[10677,3163,0.1,0.15,0.584962500721156,0.665862681409181,"*",0.546646,"AVIL","NA","GO:0051015//actin filament binding","GO:0060271//cilium assembly;GO:0007010//cytoskeleton organization;GO:0010976//positive regulation of neuron projection development","K08017//advillin","XP_012632595.1//advillin isoform X7 [Microcebus murinus]","3//A2MP1"]
[162417,2086,0.46,0.69,0.584962500721156,0.423768030086642,"*",0.27863,"NAGS","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0034618//arginine binding;GO:0004042//acetyl-CoA:L-glutamate N-acetyltransferase activity;GO:0103045//methione N-acyltransferase activity","GO:0006536//glutamate metabolic process;GO:0006526//arginine biosynthetic process;GO:0000050//urea cycle","K11067//N-acetylglutamate synthase [EC:2.3.1.1]","NP_694551.1//N-acetylglutamate synthase, mitochondrial [Homo sapiens]","2//1"]
[5207,1591,0.1,0.15,0.584962500721156,0.780806113772455,"*",0.685686,"PFKFB1","GO:0043540//6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex","GO:0004331//fructose-2,6-bisphosphate 2-phosphatase activity;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0003873//6-phosphofructo-2-kinase activity","GO:0006003//fructose 2,6-bisphosphate metabolic process;GO:0006000//fructose metabolic process","K19028//6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 1 [EC:2.7.1.105 3.1.3.46]","XP_016799129.1//PREDICTED: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X2 [Pan troglodytes];XP_008051654.1//6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X3 [Carlito syrichta];EAW93207.1//6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 [Homo sapiens]","1//3;3//A2MP1"]
[8970,481,0.38,0.57,0.584962500721156,0.780750457195809,"*",0.685686,"HIST1H2BJ","NA","NA","NA","K11252//histone H2B","XP_004019080.2//PREDICTED: histone H2B type 1 isoform X1 [Ovis aries]","3//A2MP1"]
[1912,2607,36,53.93,0.583091127293523,{"v":1.94544317472119e-25,"d":"1.95E-25"},"*",{"v":6.5522e-27,"d":"6.55E-27"},"PHC2","GO:0035102//PRC1 complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031519//PcG protein complex;GO:0000792//heterochromatin","GO:0003677//DNA binding;GO:0042802//identical protein binding;GO:0008270//zinc ion binding","GO:0007275//multicellular organism development;GO:0007283//spermatogenesis","K11457//polyhomeotic-like protein 2","NP_932157.1//polyhomeotic-like protein 2 isoform a [Homo sapiens];NP_001317417.1//polyhomeotic-like protein 2 isoform c [Homo sapiens];AAH68573.1//PHC2 protein, partial [Homo sapiens]","1//3;3//A2MP1;2//1"]
[10398,1115,1.87,2.8,0.58238855705733,0.128365080260636,"*",0.0628968,"MYL9","GO:0005859//muscle myosin complex;GO:0005829//cytosol","GO:0005509//calcium ion binding;GO:0008307//structural constituent of muscle","GO:0006937//regulation of muscle contraction;GO:0006936//muscle contraction;GO:0045652//regulation of megakaryocyte differentiation;GO:0070527//platelet aggregation","K12755//myosin regulatory light chain 9","NP_852667.1//myosin regulatory light polypeptide 9 isoform b [Homo sapiens];XP_017719010.1//PREDICTED: myosin regulatory light polypeptide 9 isoform X1 [Rhinopithecus bieti]","4;2//1"]
[10517,3293,1.39,2.08,0.581498645417585,0.0304467875268817,"*",0.01205368,"FBXW10","GO:0005829//cytosol","GO:0004842//ubiquitin-protein transferase activity","GO:0043687//post-translational protein modification;GO:0000209//protein polyubiquitination","K10266//F-box and WD-40 domain protein 10","NP_001254514.1//F-box/WD repeat-containing protein 10 isoform 1 [Homo sapiens];NP_001254515.1//F-box/WD repeat-containing protein 10 isoform 2 [Homo sapiens]","1//3"]
[404217,1290,19.69,29.4,0.578353043822173,{"v":1.78873884153005e-07,"d":"1.79E-07"},"*",{"v":2.66396e-08,"d":"2.66E-08"},"CTXN1","GO:0016021//integral component of membrane","NA","NA","K16628//collagen, type VII, alpha;K03129//transcription initiation factor TFIID subunit 4","EAW68956.1//cortexin 1, partial [Homo sapiens]","3//A2MP1"]
[4494,457,7.2,10.74,0.576925181655738,0.152146402756923,"*",0.0773876,"MT1F","NA","NA","NA","K14739//metallothionein 1/2","AAF23355.1//hqp0376 protein [Homo sapiens]","1//3;3//A2MP1"]
[84330,1377,12.13,18.06,0.574218342360348,{"v":7.36685431456311e-05,"d":"7.37E-05"},"*",{"v":1.662546e-05,"d":"1.66E-05"},"ZNF414","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K16628//collagen, type VII, alpha;K08559//nuclear receptor subfamily 4 group A member 3;K19994//PML-RARA-regulated adapter molecule 1","NP_115746.2//zinc finger protein 414 isoform 2 [Homo sapiens];NP_001139647.1//zinc finger protein 414 isoform 1 [Homo sapiens]","1//3;2//1"]
[10265,2075,2.17,3.23,0.573839122249446,0.0506698957060646,"*",0.0214968,"IRX5","GO:0005634//nucleus","GO:0005499//vitamin D binding;GO:0043565//sequence-specific DNA binding","GO:0006355//regulation of transcription, DNA-templated;GO:0060040//retinal bipolar neuron differentiation;GO:0007601//visual perception;GO:0006351//transcription, DNA-templated;GO:0002027//regulation of heart rate;GO:0008406//gonad development;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0050896//response to stimulus;GO:0042551//neuron maturation","K13046//tolkin [EC:3.4.24.-];K13172//serine/arginine repetitive matrix protein 2","NP_005844.4//iroquois-class homeodomain protein IRX-5 isoform 1 [Homo sapiens];NP_001239126.1//iroquois-class homeodomain protein IRX-5 isoform 2 [Homo sapiens]","1//3;5"]
[4255,1372,2.07,3.08,0.573299583195576,0.136613780697118,"*",0.0679648,"MGMT","GO:0016020//membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0003908//methylated-DNA-[protein]-cysteine S-methyltransferase activity;GO:0005509//calcium ion binding","GO:0042493//response to drug;GO:0043066//negative regulation of apoptotic process;GO:0009636//response to toxic substance;GO:0045471//response to ethanol;GO:0006307//DNA dealkylation involved in DNA repair;GO:0071407//cellular response to organic cyclic compound;GO:0071479//cellular response to ionizing radiation;GO:0034599//cellular response to oxidative stress;GO:0060644//mammary gland epithelial cell differentiation;GO:0043281//regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:2000781//positive regulation of double-strand break repair;GO:0045739//positive regulation of DNA repair;GO:0051593//response to folic acid;GO:0060548//negative regulation of cell death","K00567//methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]","NP_002403.2//methylated-DNA--protein-cysteine methyltransferase [Homo sapiens]",4]
[100132247,3827,7.9,11.75,0.572736198387897,{"v":8.79869525808056e-09,"d":"8.80E-09"},"*",{"v":1.107686e-09,"d":"1.11E-09"},"NPIPB5","GO:0005654//nucleoplasm;GO:0016021//integral component of membrane","NA","NA","K17582//antigen KI-67","NP_001129337.1//nuclear pore complex interacting protein family member [Homo sapiens]","1//3"]
[115708,3257,15.84,23.55,0.572154724420536,{"v":3.03533051651143e-14,"d":"3.04E-14"},"*",{"v":2.2441e-15,"d":"2.24E-15"},"TRMT61A","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031515//tRNA (m1A) methyltransferase complex","GO:0016429//tRNA (adenine-N1-)-methyltransferase activity","GO:0006400//tRNA modification","K07442//tRNA (adenine57-N1/adenine58-N1)-methyltransferase catalytic subunit [EC:2.1.1.219 2.1.1.220]","XP_007986137.1//PREDICTED: tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A [Chlorocebus sabaeus]","2//1"]
[113179,1751,7.15,10.63,0.572126449865353,0.00278892393705293,"*",0.000854276,"ADAT3","GO:0005654//nucleoplasm","GO:0046872//metal ion binding;GO:0003824//catalytic activity","GO:0006400//tRNA modification;GO:0009451//RNA modification","K15442//tRNA-specific adenosine deaminase 3","NP_612431.2//probable inactive tRNA-specific adenosine deaminase-like protein 3 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[51042,653,39.42,58.6,0.571972888266124,{"v":3.78263290249799e-07,"d":"3.78E-07"},"*",{"v":5.87736e-08,"d":"5.88E-08"},"ZNF593","GO:0005634//nucleus;GO:0005730//nucleolus;GO:0030687//preribosome, large subunit precursor","GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0043023//ribosomal large subunit binding;GO:0003676//nucleic acid binding","GO:0000055//ribosomal large subunit export from nucleus;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:1903026//negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding;GO:0006351//transcription, DNA-templated","K14821//bud site selection protein 20","NP_056955.2//zinc finger protein 593 [Homo sapiens]",4]
[83480,1687,3.38,5.02,0.570664117668587,0.040103965106383,"*",0.0165196,"PUS3","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0009982//pseudouridine synthase activity","GO:0031119//tRNA pseudouridine synthesis;GO:0006400//tRNA modification;GO:1990481//mRNA pseudouridine synthesis","K01855//tRNA pseudouridine38/39 synthase [EC:5.4.99.45]","NP_112597.3//tRNA pseudouridine(38/39) synthase isoform 1 [Homo sapiens];XP_005271744.1//PREDICTED: tRNA pseudouridine(38/39) synthase isoform X1 [Homo sapiens]","1//3;3//A2MP1"]
[158056,3669,2.81,4.17,0.569477253223738,1.45180909256449E-3,"*",0.000419256,"MAMDC4","GO:0016021//integral component of membrane","NA","GO:0015031//protein transport","K18762//zygote arrest protein 1","NP_996803.2//apical endosomal glycoprotein precursor [Homo sapiens]","2//1"]
[10435,2043,13.98,20.73,0.568355755733978,{"v":4.07398858314351e-08,"d":"4.07E-08"},"*",{"v":5.5981e-09,"d":"5.60E-09"},"CDC42EP2","GO:0016020//membrane;GO:0012505//endomembrane system;GO:0015630//microtubule cytoskeleton;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0001515//opioid peptide activity;GO:0017049//GTP-Rho binding;GO:0005096//GTPase activator activity","GO:0007266//Rho protein signal transduction;GO:0007015//actin filament organization;GO:0031334//positive regulation of protein complex assembly;GO:0030036//actin cytoskeleton organization;GO:0031274//positive regulation of pseudopodium assembly;GO:0030838//positive regulation of actin filament polymerization;GO:0008360//regulation of cell shape","NA","EAW74374.1//CDC42 effector protein (Rho GTPase binding) 2, partial [Homo sapiens]","3//A2MP1"]
[387496,1246,5.62,8.33,0.567746365144622,0.0113662884507042,"*",0.00399108,"RASL11A","GO:0016020//membrane;GO:0005730//nucleolus","GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0007165//signal transduction;GO:0006351//transcription, DNA-templated;GO:0045943//positive regulation of transcription from RNA polymerase I promoter","K07852//Ras-like protein family member 11A","NP_996563.1//ras-like protein family member 11A isoform 1 [Homo sapiens];XP_011753914.1//PREDICTED: ras-like protein family member 11A [Macaca nemestrina]","1//3"]
[55009,912,48.73,72.22,0.567588197756324,{"v":9.6622966763285e-12,"d":"9.66E-12"},"*",{"v":8.76466e-13,"d":"8.76E-13"},"C19orf24","GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005737//cytoplasm","NA","NA","K03129//transcription initiation factor TFIID subunit 4;K02891//large subunit ribosomal protein L22e","EAW69518.1//chromosome 19 open reading frame 24, isoform CRA_a [Homo sapiens]","3//A2MP1"]
[401399,2411,0.27,0.4,0.567040592723894,0.199876384425941,"*",0.106695,"PRRT4","GO:0016021//integral component of membrane","NA","NA","K16628//collagen, type VII, alpha","NP_001108198.2//proline-rich transmembrane protein 4 isoform 2 precursor [Homo sapiens];NP_001167635.1//proline-rich transmembrane protein 4 isoform 1 precursor [Homo sapiens]","1//3;2//1"]
[644890,638,0.27,0.4,0.567040592723894,0.781251652211127,"*",0.685686,"MEIG1","GO:0005634//nucleus","NA","GO:0030154//cell differentiation;GO:0007283//spermatogenesis","NA","EAW86246.1//hCG2039913, partial [Homo sapiens]","2//1"]
[140456,2748,0.75,1.11,0.565597175854225,0.191790122057089,"*",0.1017902,"ASB11","GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005622//intracellular","NA","GO:0043687//post-translational protein modification;GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction","K10333//ankyrin repeat and SOCS box protein 11","NP_543149.1//ankyrin repeat and SOCS box protein 11 isoform a [Homo sapiens];NP_001012428.1//ankyrin repeat and SOCS box protein 11 isoform b [Homo sapiens];NP_001188512.1//ankyrin repeat and SOCS box protein 11 isoform c [Homo sapiens]","1//3;2//1"]
[23305,6316,0.25,0.37,0.565597175854225,0.275350957602085,"*",0.1587224,"ACSL6","GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005741//mitochondrial outer membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005778//peroxisomal membrane","GO:0005524//ATP binding;GO:0004467//long-chain fatty acid-CoA ligase activity;GO:0003824//catalytic activity;GO:0102391//decanoate--CoA ligase activity;GO:0042803//protein homodimerization activity;GO:0019899//enzyme binding;GO:0016874//ligase activity","GO:0008152//metabolic process;GO:0035338//long-chain fatty-acyl-CoA biosynthetic process;GO:0001676//long-chain fatty acid metabolic process;GO:0006637//acyl-CoA metabolic process","K01897//long-chain acyl-CoA synthetase [EC:6.2.1.3]","XP_006872995.1//PREDICTED: long-chain-fatty-acid--CoA ligase 6 isoform X3 [Chrysochloris asiatica];XP_016808253.1//PREDICTED: long-chain-fatty-acid--CoA ligase 6 isoform X2 [Pan troglodytes];XP_016808252.1//PREDICTED: long-chain-fatty-acid--CoA ligase 6 isoform X1 [Pan troglodytes];NP_001192180.1//long-chain-fatty-acid--CoA ligase 6 isoform f [Homo sapiens]","1//3;3//A2MP1;2//1"]
[27113,1853,5.71,8.44,0.563752253344342,0.00150763771737252,"*",0.000436794,"BBC3","GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005741//mitochondrial outer membrane;GO:0005739//mitochondrion","GO:0051117//ATPase binding","GO:0071456//cellular response to hypoxia;GO:0001844//protein insertion into mitochondrial membrane involved in apoptotic signaling pathway;GO:0045926//negative regulation of growth;GO:0097190//apoptotic signaling pathway;GO:0034976//response to endoplasmic reticulum stress;GO:2001056//positive regulation of cysteine-type endopeptidase activity;GO:0097193//intrinsic apoptotic signaling pathway;GO:0006974//cellular response to DNA damage stimulus;GO:0001836//release of cytochrome c from mitochondria;GO:1900740//positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway;GO:1902237//positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway;GO:0043525//positive regulation of neuron apoptotic process;GO:0032464//positive regulation of protein homooligomerization;GO:0032471//negative regulation of endoplasmic reticulum calcium ion concentration;GO:0006915//apoptotic process;GO:0008340//determination of adult lifespan;GO:0070245//positive regulation of thymocyte apoptotic process;GO:0097194//execution phase of apoptosis;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0051209//release of sequestered calcium ion into cytosol;GO:0042981//regulation of apoptotic process;GO:1903896//positive regulation of IRE1-mediated unfolded protein response","K11653//AT-rich interactive domain-containing protein 1;K19475//WAS/WASL-interacting protein;K10132//Bcl-2-binding component 3;K20638//Rho GTPase-activating protein 17","XP_017355891.1//PREDICTED: bcl-2-binding component 3 isoform X2 [Cebus capucinus imitator];NP_001120712.1//bcl-2-binding component 3 isoform 1 [Homo sapiens];NP_001120714.1//bcl-2-binding component 3 isoform 3 [Homo sapiens]","4;2//1"]
[503542,3188,2.45,3.62,0.563207948080635,0.0072602563026784,"*",0.0024266,"SPRN","GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005576//extracellular region;GO:0031982//vesicle;GO:0005886//plasma membrane;GO:0031225//anchored component of membrane","GO:0003676//nucleic acid binding","GO:0006501//C-terminal protein lipidation;GO:0006606//protein import into nucleus","K03129//transcription initiation factor TFIID subunit 4","EAW61350.1//hCG2040575, partial [Homo sapiens]","3//A2MP1"]
[124739,4174,1.74,2.57,0.56268105334515,0.0116669573394985,"*",0.00410688,"USP43","GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0004843//thiol-dependent ubiquitin-specific protease activity;GO:0036459//thiol-dependent ubiquitinyl hydrolase activity;GO:0019785//ISG15-specific protease activity","GO:0019985//translesion synthesis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination","K11856//ubiquitin carboxyl-terminal hydrolase 43 [EC:3.4.19.12]","NP_694942.3//ubiquitin carboxyl-terminal hydrolase 43 isoform 1 [Homo sapiens];NP_001254505.1//ubiquitin carboxyl-terminal hydrolase 43 isoform 2 [Homo sapiens]","4;1//3"]
[6452,9109,2.58,3.81,0.562419932070068,{"v":7.44409305157814e-07,"d":"7.44E-07"},"*",{"v":1.210702E-7,"d":"1.21E-07"},"SH3BP2","NA","GO:0005070//SH3/SH2 adaptor activity;GO:0001784//phosphotyrosine residue binding;GO:0017124//SH3 domain binding","GO:0007165//signal transduction","K07984//SH3-domain binding protein 2","XP_018880723.1//PREDICTED: SH3 domain-binding protein 2 isoform X2 [Gorilla gorilla gorilla];NP_001139327.1//SH3 domain-binding protein 2 isoform c [Homo sapiens];NP_001139328.1//SH3 domain-binding protein 2 isoform b [Homo sapiens]","1//3;4"]
[6405,3538,2.12,3.13,0.562098392369419,0.00981992227949183,"*",0.00338724,"SEMA3F","GO:0005615//extracellular space","GO:0045499//chemorepellent activity;GO:0038191//neuropilin binding","GO:0036486//ventral trunk neural crest cell migration;GO:1902287//semaphorin-plexin signaling pathway involved in axon guidance;GO:0021612//facial nerve structural organization;GO:0048846//axon extension involved in axon guidance;GO:0021785//branchiomotor neuron axon guidance;GO:0097491//sympathetic neuron projection guidance;GO:0048843//negative regulation of axon extension involved in axon guidance;GO:0021637//trigeminal nerve structural organization;GO:0097490//sympathetic neuron projection extension;GO:1902285//semaphorin-plexin signaling pathway involved in neuron projection guidance;GO:1901166//neural crest cell migration involved in autonomic nervous system development;GO:0021675//nerve development;GO:0007411//axon guidance;GO:0061549//sympathetic ganglion development","K06840//semaphorin 3","NP_004177.3//semaphorin-3F isoform 1 precursor [Homo sapiens];BAD92496.1//semaphorin 3F variant, partial [Homo sapiens];NP_001305729.1//semaphorin-3F isoform 2 precursor [Homo sapiens]","4;1//3"]
[2670,3097,0.21,0.31,0.561878887608115,0.402888300357108,"*",0.26132,"GFAP","GO:0097450//astrocyte end-foot;GO:0044297//cell body;GO:0045111//intermediate filament cytoskeleton;GO:0005829//cytosol;GO:0043209//myelin sheath;GO:0005882//intermediate filament;GO:0005737//cytoplasm;GO:0098574//cytoplasmic side of lysosomal membrane","GO:0005178//integrin binding;GO:0042802//identical protein binding;GO:0019900//kinase binding;GO:0005200//structural constituent of cytoskeleton","GO:0009611//response to wounding;GO:0045109//intermediate filament organization;GO:0043254//regulation of protein complex assembly;GO:0014002//astrocyte development;GO:0051580//regulation of neurotransmitter uptake;GO:0010977//negative regulation of neuron projection development;GO:0030198//extracellular matrix organization;GO:0060291//long-term synaptic potentiation;GO:0031102//neuron projection regeneration;GO:0010625//positive regulation of Schwann cell proliferation;GO:1904714//regulation of chaperone-mediated autophagy;GO:0060020//Bergmann glial cell differentiation","K05640//glial fibrillary acidic protein","XP_012353064.1//PREDICTED: glial fibrillary acidic protein isoform X2 [Nomascus leucogenys];XP_003270779.2//PREDICTED: glial fibrillary acidic protein isoform X3 [Nomascus leucogenys];XP_017806300.2//glial fibrillary acidic protein isoform X2 [Papio anubis]","1//3;4;2//1"]
[11077,1916,1.05,1.55,0.561878887608115,0.229778547915028,"*",0.1279792,"HSF2BP","NA","NA","NA","NA","XP_007967686.1//PREDICTED: heat shock factor 2-binding protein isoform X2 [Chlorocebus sabaeus]","1//3"]
[4688,2285,0.4,0.59,0.560714954474479,0.495774793725632,"*",0.3423,"NCF2","GO:0032010//phagolysosome;GO:0005730//nucleolus;GO:0043020//NADPH oxidase complex;GO:0005829//cytosol;GO:0001669//acrosomal vesicle","GO:0009055//electron transfer activity;GO:0016176//superoxide-generating NADPH oxidase activator activity;GO:0008022//protein C-terminus binding;GO:0048365//Rac GTPase binding;GO:0016175//superoxide-generating NADPH oxidase activity","GO:0006801//superoxide metabolic process;GO:0034599//cellular response to oxidative stress;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0042554//superoxide anion generation;GO:0045087//innate immune response;GO:0006968//cellular defense response;GO:0045730//respiratory burst;GO:0006909//phagocytosis;GO:0045454//cell redox homeostasis","K08010//neutrophil cytosolic factor 2","XP_011850731.1//PREDICTED: neutrophil cytosol factor 2 isoform X1 [Mandrillus leucophaeus];NP_001177718.1//neutrophil cytosol factor 2 isoform 3 [Homo sapiens];NP_001177723.1//neutrophil cytosol factor 2 isoform 2 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[116372,3519,8.94,13.18,0.560003633824734,{"v":8.80208725771144e-09,"d":"8.80E-09"},"*",{"v":1.107562e-09,"d":"1.11E-09"},"LYPD1","GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane","GO:0046872//metal ion binding;GO:0004930//G-protein coupled receptor activity","GO:0007186//G-protein coupled receptor signaling pathway","K08412//G protein-coupled receptor 39","XP_017391561.1//PREDICTED: ly6/PLAUR domain-containing protein 1 isoform X1 [Cebus capucinus imitator];XP_011825690.1//PREDICTED: ly6/PLAUR domain-containing protein 1 isoform X1 [Mandrillus leucophaeus];XP_007962958.1//PREDICTED: G-protein coupled receptor 39-like [Chlorocebus sabaeus]","6;1//3;3//A2MP1"]
[4828,1044,19.1,28.14,0.559049690313422,{"v":1.17671902139891E-5,"d":"1.18E-05"},"*",{"v":2.30644e-06,"d":"2.31E-06"},"NMB","GO:0005576//extracellular region;GO:0043005//neuron projection","GO:0031710//neuromedin B receptor binding;GO:0005179//hormone activity","GO:0046887//positive regulation of hormone secretion;GO:0050482//arachidonic acid secretion;GO:0007165//signal transduction;GO:0046888//negative regulation of hormone secretion;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007267//cell-cell signaling;GO:0007218//neuropeptide signaling pathway;GO:0008284//positive regulation of cell proliferation;GO:0042593//glucose homeostasis","K05223//neuromedin B","NP_995580.1//neuromedin-B isoform 2 preproprotein [Homo sapiens];NP_066563.2//neuromedin-B isoform 1 preproprotein [Homo sapiens]","1//3;3//A2MP1"]
[100170229,2415,4.63,6.82,0.558759545763936,0.00124702407464325,"*",0.00035559,"SRRM5","NA","NA","NA","K17498//transcription factor SPN1","BAG60212.1//unnamed protein product [Homo sapiens]","1//3"]
[55512,5269,0.36,0.53,0.557995453120887,0.266378345531915,"*",0.1528332,"SMPD3","GO:0016021//integral component of membrane;GO:0000137//Golgi cis cisterna;GO:0005886//plasma membrane;GO:0000139//Golgi membrane","GO:0046872//metal ion binding;GO:0004767//sphingomyelin phosphodiesterase activity","GO:0006685//sphingomyelin catabolic process;GO:1903543//positive regulation of exosomal secretion;GO:0030072//peptide hormone secretion;GO:0002244//hematopoietic progenitor cell differentiation;GO:0006687//glycosphingolipid metabolic process;GO:2000304//positive regulation of ceramide biosynthetic process;GO:0007049//cell cycle;GO:0006684//sphingomyelin metabolic process","K12352//sphingomyelin phosphodiesterase 3 [EC:3.1.4.12]","NP_061137.1//sphingomyelin phosphodiesterase 3 [Homo sapiens]","3//A2MP1"]
[344838,2119,2.16,3.18,0.557995453120887,0.0526002674493689,"*",0.0224376,"PAQR9","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0003707//steroid hormone receptor activity;GO:0005496//steroid binding","GO:0048545//response to steroid hormone","K10955//mucin-2","XP_016797594.1//PREDICTED: progestin and adipoQ receptor family member 9 isoform X1 [Pan troglodytes]","2//1"]
[80328,1424,1.25,1.84,0.557777671394926,0.235673703222919,"*",0.131838,"ULBP2","GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0009986//cell surface;GO:0005576//extracellular region;GO:0046658//anchored component of plasma membrane;GO:0031225//anchored component of membrane;GO:0005886//plasma membrane","GO:0046703//natural killer cell lectin-like receptor binding","GO:0030101//natural killer cell activation;GO:0006501//C-terminal protein lipidation;GO:0042267//natural killer cell mediated cytotoxicity;GO:0016032//viral process","K07986//UL16 binding protein;K07987//retinoic acid early transcript 1","NP_079493.1//NKG2D ligand 2 preproprotein [Homo sapiens]","3//A2MP1"]
[23659,2764,3.92,5.77,0.557717664530274,0.00152384578363204,"*",0.000441776,"PLA2G15","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0005654//nucleoplasm;GO:0005615//extracellular space;GO:0005764//lysosome;GO:0005576//extracellular region;GO:0005739//mitochondrion","GO:0004622//lysophospholipase activity;GO:0047499//calcium-independent phospholipase A2 activity;GO:0005543//phospholipid binding;GO:0008374//O-acyltransferase activity","GO:0006650//glycerophospholipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0034638//phosphatidylcholine catabolic process;GO:0046338//phosphatidylethanolamine catabolic process;GO:0009062//fatty acid catabolic process;GO:0006629//lipid metabolic process;GO:0006672//ceramide metabolic process","K06129//lysophospholipase III [EC:3.1.1.5]","NP_036452.1//group XV phospholipase A2 precursor [Homo sapiens]","3//A2MP1"]
[57053,2024,0.53,0.78,0.557481764299049,0.440128143004598,"*",0.29363,"CHRNA10","GO:0016020//membrane;GO:0030424//axon;GO:0005892//acetylcholine-gated channel complex;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0045211//postsynaptic membrane;GO:0043204//perikaryon","GO:0005102//receptor binding;GO:0005262//calcium channel activity;GO:0022848//acetylcholine-gated cation-selective channel activity","GO:0007271//synaptic transmission, cholinergic;GO:0042472//inner ear morphogenesis;GO:0050910//detection of mechanical stimulus involved in sensory perception of sound;GO:0042127//regulation of cell proliferation;GO:0007204//positive regulation of cytosolic calcium ion concentration","K04811//nicotinic acetylcholine receptor alpha-10","AAI36251.1//CHRNA10 protein, partial [Homo sapiens];NP_065135.2//neuronal acetylcholine receptor subunit alpha-10 isoform a precursor [Homo sapiens]","1//3;3//A2MP1"]
[2622,3215,8.97,13.2,0.557358039326554,{"v":1.20325240845921e-07,"d":"1.20E-07"},"*",{"v":1.745296e-08,"d":"1.75E-08"},"GAS8","GO:0036126//sperm flagellum;GO:0005929//cilium;GO:0036064//ciliary basal body;GO:0005874//microtubule;GO:0031514//motile cilium;GO:0005794//Golgi apparatus;GO:0005930//axoneme","GO:0017137//Rab GTPase binding;GO:0008017//microtubule binding","GO:0060294//cilium movement involved in cell motility;GO:0030317//flagellated sperm motility;GO:0007368//determination of left/right symmetry;GO:0007420//brain development;GO:0003351//epithelial cilium movement;GO:0048870//cell motility;GO:1904526//regulation of microtubule binding;GO:0035082//axoneme assembly;GO:0034613//cellular protein localization;GO:0008285//negative regulation of cell proliferation","K19942//growth arrest-specific protein 8","NP_001472.1//growth arrest-specific protein 8 isoform a [Homo sapiens]","1//3;2//1"]
[50632,983,0.34,0.5,0.556393348524385,0.66606584317315,"*",0.546646,"CALY","GO:0005768//endosome;GO:0005887//integral component of plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0016021//integral component of membrane;GO:0030659//cytoplasmic vesicle membrane","GO:0032051//clathrin light chain binding;GO:0032403//protein complex binding","GO:0016197//endosomal transport;GO:0048268//clathrin coat assembly;GO:0006897//endocytosis;GO:0045807//positive regulation of endocytosis;GO:0007212//dopamine receptor signaling pathway","K15493//neuron-specific vesicular protein calcyon","NP_001308546.1//neuron-specific vesicular protein calcyon isoform 2 [Homo sapiens];NP_056537.1//neuron-specific vesicular protein calcyon isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[54531,2737,10.67,15.68,0.555365383290783,{"v":6.08473617445483e-08,"d":"6.08E-08"},"*",{"v":8.55916e-09,"d":"8.56E-09"},"MIER2","GO:0005634//nucleus;GO:0043234//protein complex;GO:0005737//cytoplasm","GO:0004407//histone deacetylase activity;GO:0003677//DNA binding;GO:0042826//histone deacetylase binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0016575//histone deacetylation","K11660//metastasis-associated protein MTA;K16912//ribosomal biogenesis protein LAS1","XP_005259639.1//PREDICTED: mesoderm induction early response protein 2 isoform X3 [Homo sapiens];NP_060020.1//mesoderm induction early response protein 2 isoform 1 [Homo sapiens]","1//3;2//1"]
[135154,526,2.79,4.1,0.555358787676258,0.35803276,"*",0.219652,"SDHAF4","GO:0005759//mitochondrial matrix;GO:0005749//mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone);GO:0005739//mitochondrion","GO:0008177//succinate dehydrogenase (ubiquinone) activity","GO:0003407//neural retina development;GO:0034553//mitochondrial respiratory chain complex II assembly;GO:0045333//cellular respiration;GO:0045087//innate immune response","NA","NP_660310.2//succinate dehydrogenase assembly factor 4, mitochondrial precursor [Homo sapiens]","2//1"]
[10500,3923,1.13,1.66,0.554860468931737,0.0605712701471012,"*",0.0262928,"SEMA6C","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane","NA","GO:0007411//axon guidance","K06842//semaphorin 6","NP_001171533.1//semaphorin-6C isoform 3 precursor [Homo sapiens];NP_001171532.1//semaphorin-6C isoform 1 precursor [Homo sapiens];NP_112175.2//semaphorin-6C isoform 2 precursor [Homo sapiens]","1//3;4"]
[3700,3193,0.32,0.47,0.554588851677637,0.440169446321321,"*",0.29363,"ITIH4","GO:0070062//extracellular exosome;GO:0072562//blood microparticle;GO:0031089//platelet dense granule lumen;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0004867//serine-type endopeptidase inhibitor activity;GO:0004866//endopeptidase inhibitor activity","GO:0002576//platelet degranulation;GO:0034097//response to cytokine;GO:0006953//acute-phase response;GO:0030212//hyaluronan metabolic process","K19014//inter-alpha-trypsin inhibitor heavy chain H1;K19015//inter-alpha-trypsin inhibitor heavy chain H2","NP_001159921.1//inter-alpha-trypsin inhibitor heavy chain H4 isoform 2 precursor [Homo sapiens];NP_002209.2//inter-alpha-trypsin inhibitor heavy chain H4 isoform 1 precursor [Homo sapiens]","1//3;4"]
[3037,3275,1.75,2.57,0.554413437361549,0.026845007388576,"*",0.01044458,"HAS2","GO:0005887//integral component of plasma membrane;GO:0005737//cytoplasm","GO:0050501//hyaluronan synthase activity","GO:0030335//positive regulation of cell migration;GO:0001822//kidney development;GO:0071498//cellular response to fluid shear stress;GO:0071356//cellular response to tumor necrosis factor;GO:0044849//estrous cycle;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:1900625//positive regulation of monocyte aggregation;GO:0045226//extracellular polysaccharide biosynthetic process;GO:0090500//endocardial cushion to mesenchymal transition;GO:0071347//cellular response to interleukin-1;GO:0051549//positive regulation of keratinocyte migration;GO:0085029//extracellular matrix assembly;GO:0030213//hyaluronan biosynthetic process;GO:0036120//cellular response to platelet-derived growth factor stimulus;GO:0001570//vasculogenesis;GO:0014911//positive regulation of smooth muscle cell migration;GO:0060349//bone morphogenesis;GO:0070295//renal water absorption;GO:0010838//positive regulation of keratinocyte proliferation;GO:0007155//cell adhesion;GO:1900127//positive regulation of hyaluronan biosynthetic process;GO:0035810//positive regulation of urine volume;GO:1901201//regulation of extracellular matrix assembly;GO:0036302//atrioventricular canal development;GO:0008284//positive regulation of cell proliferation","K00752//hyaluronan synthase [EC:2.4.1.212]","NP_005319.1//hyaluronan synthase 2 [Homo sapiens]","2//1"]
[11007,1277,44.64,65.55,0.554258753279929,{"v":2.49690613617021e-14,"d":"2.50E-14"},"*",{"v":1.83665E-15,"d":"1.84E-15"},"CCDC85B","GO:0005634//nucleus;GO:0005813//centrosome;GO:0005737//cytoplasm","NA","GO:0045892//negative regulation of transcription, DNA-templated;GO:0030308//negative regulation of cell growth;GO:0030154//cell differentiation;GO:0006351//transcription, DNA-templated;GO:0045599//negative regulation of fat cell differentiation","K16758//coiled-coil domain-containing protein 85B","NP_006839.2//coiled-coil domain-containing protein 85B [Homo sapiens]","2//1"]
[5970,2595,61.22,89.87,0.553836557255989,{"v":3.4724506474359e-39,"d":"3.47E-39"},"*",{"v":6.7823e-41,"d":"6.78E-41"},"RELA","GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0005737//cytoplasm;GO:0035525//NF-kappaB p50/p65 complex;GO:0033256//I-kappaB/NF-kappaB complex;GO:0071159//NF-kappaB complex;GO:0005829//cytosol;GO:0005667//transcription factor complex","GO:0003677//DNA binding;GO:0001205//transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0047485//protein N-terminus binding;GO:0031625//ubiquitin protein ligase binding;GO:0046982//protein heterodimerization activity;GO:0031490//chromatin DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0019901//protein kinase binding;GO:0042301//phosphate ion binding;GO:0003682//chromatin binding;GO:0033613//activating transcription factor binding;GO:0003700//DNA binding transcription factor activity;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0042826//histone deacetylase binding;GO:0070491//repressing transcription factor binding;GO:0000983//transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding;GO:0042803//protein homodimerization activity;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0042805//actinin binding;GO:0051059//NF-kappaB binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0071532//ankyrin repeat binding","GO:1902895//positive regulation of pri-miRNA transcription from RNA polymerase II promoter;GO:0071316//cellular response to nicotine;GO:0006117//acetaldehyde metabolic process;GO:0042177//negative regulation of protein catabolic process;GO:0071222//cellular response to lipopolysaccharide;GO:0033234//negative regulation of protein sumoylation;GO:0071347//cellular response to interleukin-1;GO:0071354//cellular response to interleukin-6;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:0070301//cellular response to hydrogen peroxide;GO:0035994//response to muscle stretch;GO:0045084//positive regulation of interleukin-12 biosynthetic process;GO:0035729//cellular response to hepatocyte growth factor stimulus;GO:0071375//cellular response to peptide hormone stimulus;GO:0043620//regulation of DNA-templated transcription in response to stress;GO:1901522//positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:1901223//negative regulation of NIK/NF-kappaB signaling;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0001889//liver development;GO:0032495//response to muramyl dipeptide;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0071223//cellular response to lipoteichoic acid;GO:0070431//nucleotide-binding oligomerization domain containing 2 signaling pathway;GO:0010224//response to UV-B;GO:0006968//cellular defense response;GO:0006954//inflammatory response;GO:0007568//aging;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0050727//regulation of inflammatory response;GO:0071224//cellular response to peptidoglycan;GO:0009887//animal organ morphogenesis;GO:2000630//positive regulation of miRNA metabolic process;GO:0001942//hair follicle development;GO:0050862//positive regulation of T cell receptor signaling pathway;GO:0008284//positive regulation of cell proliferation","K04735//transcription factor p65","NP_001230914.1//transcription factor p65 isoform 4 [Homo sapiens];NP_001138610.1//transcription factor p65 isoform 2 [Homo sapiens];NP_068810.3//transcription factor p65 isoform 1 [Homo sapiens];NP_001230913.1//transcription factor p65 isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[64582,1834,0.75,1.1,0.552541023028779,0.357996229772472,"*",0.219652,"GPR135","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004930//G-protein coupled receptor activity","NA","K08427//G protein-coupled receptor 135","NP_072093.2//probable G-protein coupled receptor 135 [Homo sapiens]",5]
[152756,2197,0.15,0.22,0.552541023028779,0.665659643543223,"*",0.546646,"FAM218A","NA","NA","NA","K12029//tripartite motif-containing protein 60/61","NP_694572.1//protein FAM218A [Homo sapiens]","2//1"]
[728537,1109,0.15,0.22,0.552541023028779,0.780249904829748,"*",0.685686,"C2orf92","NA","NA","NA","NA","NP_001338297.1//uncharacterized protein LOC728537 precursor [Homo sapiens]","1//3"]
[475,498,73.61,107.95,0.552389566932803,{"v":6.20956190553581e-09,"d":"6.21E-09"},"*",{"v":7.65408e-10,"d":"7.65E-10"},"ATOX1","GO:0005623//cell","GO:0032767//copper-dependent protein binding;GO:0016531//copper chaperone activity","GO:0006878//cellular copper ion homeostasis;GO:0006825//copper ion transport","K07213//copper chaperone","XP_012321739.1//copper transport protein ATOX1 [Aotus nancymaae]","3//A2MP1"]
[6891,3981,9.69,14.21,0.552337983827699,{"v":5.29671593767705e-12,"d":"5.30E-12"},"*",{"v":4.68196e-13,"d":"4.68E-13"},"TAP2","GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0016607//nuclear speck;GO:0030670//phagocytic vesicle membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0042825//TAP complex;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0046978//TAP1 binding;GO:0005524//ATP binding;GO:0023029//MHC class Ib protein binding;GO:0042287//MHC protein binding;GO:0015433//peptide antigen-transporting ATPase activity;GO:0015440//peptide-transporting ATPase activity;GO:0046980//tapasin binding;GO:0005215//transporter activity","GO:1990668//vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane;GO:0002489//antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent;GO:0046967//cytosol to ER transport;GO:0016032//viral process;GO:0019885//antigen processing and presentation of endogenous peptide antigen via MHC class I;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0002250//adaptive immune response;GO:0046968//peptide antigen transport;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0015031//protein transport","K05654//ATP-binding cassette, subfamily B (MDR/TAP), member 3","BAD92190.1//transporter 2, ATP-binding cassette, sub-family B isoform 1 variant, partial [Homo sapiens];NP_061313.2//antigen peptide transporter 2 isoform 2 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[125206,2071,3.7,5.42,0.550767580837559,0.0148236616701317,"*",0.00535634,"SLC5A10","GO:0070062//extracellular exosome;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005412//glucose:sodium symporter activity;GO:0005215//transporter activity;GO:0015370//solute:sodium symporter activity","GO:0055085//transmembrane transport;GO:0006814//sodium ion transport;GO:0008645//hexose transport;GO:1904659//glucose transmembrane transport","K14390//solute carrier family 5 (sodium/glucose cotransporter), member 10","XP_016787745.1//PREDICTED: sodium/glucose cotransporter 5 isoform X2 [Pan troglodytes];XP_016787744.1//PREDICTED: sodium/glucose cotransporter 5 isoform X1 [Pan troglodytes];XP_011521955.1//PREDICTED: sodium/glucose cotransporter 5 isoform X3 [Homo sapiens];NP_001257578.1//sodium/glucose cotransporter 5 isoform 4 [Homo sapiens]","4;1//3;2//1"]
[100130933,842,5.53,8.1,0.55064242753728,0.0605800068080196,"*",0.0262928,"SMIM6","GO:0016021//integral component of membrane","NA","NA","NA","NP_001156469.1//small integral membrane protein 6 [Homo sapiens]","1//3"]
[10014,5325,3.68,5.39,0.550579506695492,{"v":1.4076494655717E-5,"d":"1.41E-05"},"*",{"v":2.78992e-06,"d":"2.79E-06"},"HDAC5","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016607//nuclear speck;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0043234//protein complex;GO:0000118//histone deacetylase complex","GO:0004407//histone deacetylase activity;GO:0042826//histone deacetylase binding;GO:0070491//repressing transcription factor binding;GO:0033558//protein deacetylase activity;GO:0032041//NAD-dependent histone deacetylase activity (H3-K14 specific);GO:0046872//metal ion binding;GO:0005080//protein kinase C binding;GO:0001025//RNA polymerase III transcription factor binding;GO:0003682//chromatin binding;GO:0008134//transcription factor binding;GO:0001047//core promoter binding","GO:0090051//negative regulation of cell migration involved in sprouting angiogenesis;GO:0006338//chromatin remodeling;GO:0071222//cellular response to lipopolysaccharide;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0030183//B cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0042493//response to drug;GO:0043393//regulation of protein binding;GO:0040029//regulation of gene expression, epigenetic;GO:0006342//chromatin silencing;GO:0030182//neuron differentiation;GO:0010832//negative regulation of myotube differentiation;GO:0014823//response to activity;GO:0006351//transcription, DNA-templated;GO:0006954//inflammatory response;GO:0032869//cellular response to insulin stimulus;GO:0010830//regulation of myotube differentiation;GO:0006325//chromatin organization;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0042220//response to cocaine;GO:0016575//histone deacetylation;GO:0042113//B cell activation;GO:0006476//protein deacetylation","K11406//histone deacetylase 4/5 [EC:3.5.1.98]","NP_001015053.1//histone deacetylase 5 isoform 3 [Homo sapiens];NP_005465.2//histone deacetylase 5 isoform 1 [Homo sapiens]","4;1//3"]
[2674,9349,0.28,0.41,0.550197082560479,0.222782662220694,"*",0.1217118,"GFRA1","GO:0070062//extracellular exosome;GO:0019898//extrinsic component of membrane;GO:0005622//intracellular;GO:0005886//plasma membrane;GO:0031225//anchored component of membrane","GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0016167//glial cell-derived neurotrophic factor receptor activity;GO:0004872//receptor activity;GO:0005102//receptor binding","GO:0007399//nervous system development;GO:0000165//MAPK cascade;GO:0007166//cell surface receptor signaling pathway;GO:0007411//axon guidance","K19895//GDNF family receptor alpha 1","XP_011715065.1//PREDICTED: GDNF family receptor alpha-1 isoform X2 [Macaca nemestrina];XP_011715075.1//PREDICTED: GDNF family receptor alpha-1 isoform X3 [Macaca nemestrina];NP_005255.1//GDNF family receptor alpha-1 isoform a preproprotein [Homo sapiens]","4;1//3;2//1;5"]
[1848,3385,3.02,4.42,0.549497820066353,2.35635089858687E-3,"*",0.000709826,"DUSP6","GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0017017//MAP kinase tyrosine/serine/threonine phosphatase activity;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity","GO:0014070//response to organic cyclic compound;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0060420//regulation of heart growth;GO:0000188//inactivation of MAPK activity;GO:0043065//positive regulation of apoptotic process;GO:0010942//positive regulation of cell death;GO:0009953//dorsal/ventral pattern formation;GO:0000165//MAPK cascade;GO:0042493//response to drug;GO:0000187//activation of MAPK activity;GO:0030154//cell differentiation;GO:0042663//regulation of endodermal cell fate specification;GO:0051409//response to nitrosative stress;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0070848//response to growth factor;GO:0040036//regulation of fibroblast growth factor receptor signaling pathway","K04459//dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48];K21946//dual specificity phosphatase 6 [EC:3.1.3.16 3.1.3.48]","NP_073143.2//dual specificity protein phosphatase 6 isoform b [Homo sapiens];XP_004845044.2//dual specificity protein phosphatase 6 isoform X1 [Heterocephalus glaber]","3//A2MP1"]
[157777,4947,0.41,0.6,0.549338590990435,0.149303021793921,"*",0.0756516,"MCMDC2","NA","GO:0003677//DNA binding;GO:0005524//ATP binding","GO:0007130//synaptonemal complex assembly;GO:1990918//double-strand break repair involved in meiotic recombination;GO:0048477//oogenesis;GO:0042140//late meiotic recombination nodule assembly;GO:0006270//DNA replication initiation;GO:0007283//spermatogenesis","K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K17985//activating molecule in BECN1-regulated autophagy protein 1;K10738//DNA helicase MCM9 [EC:3.6.4.12]","NP_001129633.1//MCM domain-containing protein 2 isoform c [Homo sapiens];NP_001129632.1//MCM domain-containing protein 2 isoform b [Homo sapiens];NP_775789.3//MCM domain-containing protein 2 isoform a [Homo sapiens]","1//3;4"]
[207063,2596,10.36,15.16,0.549245750484538,{"v":3.06979174267101e-07,"d":"3.07E-07"},"*",{"v":4.7198e-08,"d":"4.72E-08"},"DHRSX","GO:0005576//extracellular region","GO:0016491//oxidoreductase activity","GO:0010508//positive regulation of autophagy","K11170//dehydrogenase/reductase SDR family member X [EC:1.1.-.-]","NP_660160.2//dehydrogenase/reductase SDR family member on chromosome X [Homo sapiens]","2//1"]
[441250,3171,0.67,0.98,0.548620653657436,0.239122088973299,"*",0.1339916,"TYW1B","GO:0016021//integral component of membrane","GO:0102521//tRNA-4-demethylwyosine synthase activity;GO:0046872//metal ion binding;GO:0010181//FMN binding;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0003824//catalytic activity","GO:0055114//oxidation-reduction process;GO:0008033//tRNA processing","K15449//tRNA wybutosine-synthesizing protein 1 [EC:4.1.3.44]","NP_001138912.2//S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase [Homo sapiens]","2//1"]
[49856,1708,8.26,12.08,0.548406767905633,0.000337179727353376,"*",{"v":8.56564e-05,"d":"8.57E-05"},"WRAP73","GO:0036064//ciliary basal body;GO:0005814//centriole;GO:0005813//centrosome","NA","GO:1902857//positive regulation of non-motile cilium assembly;GO:0090307//mitotic spindle assembly;GO:0030030//cell projection organization","NA","NP_060288.3//WD repeat-containing protein WRAP73 [Homo sapiens]","3//A2MP1"]
[3953,3051,7.83,11.45,0.548263385693266,{"v":2.6813669037037e-06,"d":"2.68E-06"},"*",{"v":4.75878e-07,"d":"4.76E-07"},"LEPR","GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0043235//receptor complex","GO:0038021//leptin receptor activity;GO:0042802//identical protein binding;GO:0004888//transmembrane signaling receptor activity","GO:0008203//cholesterol metabolic process;GO:0007166//cell surface receptor signaling pathway;GO:0045721//negative regulation of gluconeogenesis;GO:0042593//glucose homeostasis;GO:0097009//energy homeostasis;GO:0019953//sexual reproduction;GO:0044321//response to leptin;GO:0098868//bone growth;GO:0006112//energy reserve metabolic process;GO:0033210//leptin-mediated signaling pathway;GO:0046850//regulation of bone remodeling;GO:0051346//negative regulation of hydrolase activity;GO:0006909//phagocytosis;GO:0001525//angiogenesis;GO:0060259//regulation of feeding behavior;GO:0007275//multicellular organism development;GO:0010507//negative regulation of autophagy;GO:0030217//T cell differentiation;GO:2000505//regulation of energy homeostasis","K05062//leptin receptor","NP_002294.2//leptin receptor isoform 1 precursor [Homo sapiens];NP_001003679.1//leptin receptor isoform 3 precursor [Homo sapiens];NP_001185617.1//leptin receptor isoform 4 precursor [Homo sapiens];NP_001003680.1//leptin receptor isoform 2 precursor [Homo sapiens]","1//3;3//A2MP1;5"]
[93082,1770,0.52,0.76,0.547487795302493,0.495864713884103,"*",0.3423,"NEURL3","NA","GO:0061630//ubiquitin protein ligase activity;GO:0046872//metal ion binding","NA","K15689//E3 ubiquitin-protein ligase NEURL3 [EC:2.3.2.27]","EAW71368.1//hCG1641111, isoform CRA_a, partial [Homo sapiens];XP_011911136.1//PREDICTED: E3 ubiquitin-protein ligase NEURL3 [Cercocebus atys]","1//3"]
[114299,9500,0.13,0.19,0.547487795302493,0.393221434372875,"*",0.253376,"PALM2","GO:0005886//plasma membrane","NA","GO:0008360//regulation of cell shape","K16519//A-kinase anchor protein 2","XP_003260389.2//PREDICTED: paralemmin-2 isoform X1 [Nomascus leucogenys];NP_001032370.1//paralemmin-2 isoform b [Homo sapiens]","2//1;5"]
[283403,1292,0.13,0.19,0.547487795302493,0.781697699400514,"*",0.685686,"C12orf80","NA","NA","NA","NA","EAW58238.1//hCG2038621, partial [Homo sapiens]","1//3"]
[4584,11361,0.39,0.57,0.547487795302493,0.0744165215735685,"*",0.0332764,"MUC3A","GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005796//Golgi lumen","GO:0005201//extracellular matrix structural constituent;GO:0030197//extracellular matrix constituent, lubricant activity","GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0016266//O-glycan processing","K22016//mucin-3/17","NP_005951.1//mucin-3A precursor [Homo sapiens]","1//3"]
[56624,4700,0.13,0.19,0.547487795302493,0.512037040667923,"*",0.357054,"ASAH2","GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005886//plasma membrane","GO:0017040//ceramidase activity","GO:0007165//signal transduction;GO:0006672//ceramide metabolic process;GO:0006915//apoptotic process","K12349//neutral ceramidase [EC:3.5.1.23]","NP_063946.2//neutral ceramidase isoform a [Homo sapiens];NP_001137446.1//neutral ceramidase isoform b [Homo sapiens]","3//A2MP1;2//1"]
[160140,1274,0.13,0.19,0.547487795302493,0.780138758119658,"*",0.685686,"C11orf65","NA","NA","NA","NA","NP_001338039.1//uncharacterized protein C11orf65 isoform 3 [Homo sapiens];NP_001317297.1//uncharacterized protein C11orf65 isoform 2 [Homo sapiens];NP_689800.3//uncharacterized protein C11orf65 isoform 1 [Homo sapiens]","4;1//3"]
[23710,1885,10.66,15.57,0.546561506319861,{"v":1.50732369230769e-05,"d":"1.51E-05"},"*",{"v":3.0054e-06,"d":"3.01E-06"},"GABARAPL1","GO:0016020//membrane;GO:0032839//dendrite cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005874//microtubule;GO:0005622//intracellular;GO:0044297//cell body;GO:0032590//dendrite membrane;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0005739//mitochondrion;GO:0005776//autophagosome;GO:0000421//autophagosome membrane;GO:0030659//cytoplasmic vesicle membrane","GO:0050811//GABA receptor binding;GO:0048487//beta-tubulin binding;GO:0008092//cytoskeletal protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0030957//Tat protein binding","GO:0097352//autophagosome maturation;GO:0006995//cellular response to nitrogen starvation;GO:0006914//autophagy;GO:0000045//autophagosome assembly;GO:0016236//macroautophagy;GO:0000422//autophagy of mitochondrion","K08341//GABA(A) receptor-associated protein","XP_010984496.1//PREDICTED: gamma-aminobutyric acid receptor-associated protein-like 1 [Camelus dromedarius]","2//1"]
[10848,3121,6.3,9.2,0.546282032557096,{"v":1.60452946941323E-5,"d":"1.60E-05"},"*",{"v":3.2183e-06,"d":"3.22E-06"},"PPP1R13L","GO:0045171//intercellular bridge;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0030054//cell junction","GO:0003714//transcription corepressor activity;GO:0042802//identical protein binding;GO:0008134//transcription factor binding;GO:0045296//cadherin binding","GO:0003229//ventricular cardiac muscle tissue development;GO:0006351//transcription, DNA-templated;GO:0031076//embryonic camera-type eye development;GO:0035264//multicellular organism growth;GO:0006915//apoptotic process;GO:1901796//regulation of signal transduction by p53 class mediator;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0009791//post-embryonic development;GO:0060048//cardiac muscle contraction;GO:0042633//hair cycle;GO:0003215//cardiac right ventricle morphogenesis;GO:0048871//multicellular organismal homeostasis;GO:0045597//positive regulation of cell differentiation","K17554//apoptosis-stimulating of p53 protein 1;K16823//apoptosis-stimulating of p53 protein 2","XP_005589646.1//PREDICTED: relA-associated inhibitor isoform X1 [Macaca fascicularis];XP_512747.4//PREDICTED: relA-associated inhibitor isoform X1 [Pan troglodytes]","1//3;3//A2MP1"]
[115399,2789,0.5,0.73,0.545968369105293,0.358105842825066,"*",0.219652,"LRRC56","NA","NA","NA","K16628//collagen, type VII, alpha;K06236//collagen, type I, alpha","NP_932341.1//leucine-rich repeat-containing protein 56 [Homo sapiens]","3//A2MP1"]
[10957,2133,13.64,19.91,0.54564957669633,{"v":1.2378434060241E-7,"d":"1.24E-07"},"*",{"v":1.800894E-8,"d":"1.80E-08"},"PNRC1","GO:0005634//nucleus;GO:0000932//P-body","NA","GO:0006355//regulation of transcription, DNA-templated;GO:0031087//deadenylation-independent decapping of nuclear-transcribed mRNA;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006351//transcription, DNA-templated","K18774//proline-rich nuclear receptor coactivator 1","NP_006804.1//proline-rich nuclear receptor coactivator 1 [Homo sapiens]","2//1"]
[79005,2051,2.96,4.32,0.545434136534519,0.0298477270211078,"*",0.01177354,"SCNM1","GO:0016607//nuclear speck","GO:0046872//metal ion binding;GO:0019899//enzyme binding","GO:0006397//mRNA processing;GO:0008380//RNA splicing","K12581//CCR4-NOT transcription complex subunit 7/8;K07560//D-tyrosyl-tRNA(Tyr) deacylase [EC:3.1.-.-];K16506//protocadherin Fat 1/2/3;K18047//serine/threonine/tyrosine-interacting-like protein 1;K04487//cysteine desulfurase [EC:2.8.1.7]","XP_011767573.1//PREDICTED: sodium channel modifier 1 [Macaca nemestrina]","1//3;3//A2MP1"]
[138429,1543,1.09,1.59,0.544698630507429,0.344814087764584,"*",0.20906,"PIP5KL1","GO:0016020//membrane;GO:0042995//cell projection;GO:0005829//cytosol","GO:0005524//ATP binding;GO:0016308//1-phosphatidylinositol-4-phosphate 5-kinase activity","NA","K13712//phosphatidylinositol-4-phosphate 5-kinase-like protein 1 [EC:2.7.1.68]","XP_004048716.1//PREDICTED: phosphatidylinositol 4-phosphate 5-kinase-like protein 1 [Gorilla gorilla gorilla];XP_520281.3//PREDICTED: phosphatidylinositol 4-phosphate 5-kinase-like protein 1 isoform X1 [Pan troglodytes]","1//3"]
[4938,1757,12.22,17.82,0.544253051703192,{"v":2.94459482848123e-06,"d":"2.94E-06"},"*",{"v":5.25544e-07,"d":"5.26E-07"},"OAS1","GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005576//extracellular region;GO:0005739//mitochondrion;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0005524//ATP binding;GO:0008270//zinc ion binding;GO:0001730//2'-5'-oligoadenylate synthetase activity;GO:0003725//double-stranded RNA binding","GO:0060333//interferon-gamma-mediated signaling pathway;GO:0006006//glucose metabolic process;GO:0060337//type I interferon signaling pathway;GO:0051607//defense response to virus;GO:0060700//regulation of ribonuclease activity;GO:0042593//glucose homeostasis;GO:0045071//negative regulation of viral genome replication;GO:0006955//immune response;GO:0006164//purine nucleotide biosynthetic process;GO:0009615//response to virus;GO:0035457//cellular response to interferon-alpha;GO:0051259//protein oligomerization","K14216//2'-5'-oligoadenylate synthetase [EC:2.7.7.84]","NP_001126043.1//2'-5'-oligoadenylate synthase 1 [Pongo abelii];NP_001027581.1//2'-5'-oligoadenylate synthase 1 isoform 3 [Homo sapiens];XP_011853298.1//PREDICTED: 2'-5'-oligoadenylate synthase 1 isoform X1 [Mandrillus leucophaeus];XP_011853299.1//PREDICTED: 2'-5'-oligoadenylate synthase 1 isoform X2 [Mandrillus leucophaeus]","1//3;3//A2MP1;2//1"]
[1839,2381,1.75,2.55,0.543142325026529,0.0744050221786614,"*",0.0332666,"HBEGF","GO:0005615//extracellular space;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0030666//endocytic vesicle membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0030669//clathrin-coated endocytic vesicle membrane","GO:0004713//protein tyrosine kinase activity;GO:0008083//growth factor activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0008201//heparin binding;GO:0005154//epidermal growth factor receptor binding;GO:0046934//phosphatidylinositol-4,5-bisphosphate 3-kinase activity","GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0051897//positive regulation of protein kinase B signaling;GO:0030335//positive regulation of cell migration;GO:0030307//positive regulation of cell growth;GO:1901185//negative regulation of ERBB signaling pathway;GO:0008016//regulation of heart contraction;GO:0060326//cell chemotaxis;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0051549//positive regulation of keratinocyte migration;GO:0000165//MAPK cascade;GO:0007165//signal transduction;GO:0014066//regulation of phosphatidylinositol 3-kinase signaling;GO:0038128//ERBB2 signaling pathway;GO:0007517//muscle organ development;GO:2000145//regulation of cell motility;GO:0051545//negative regulation of elastin biosynthetic process;GO:0038111//interleukin-7-mediated signaling pathway;GO:0090303//positive regulation of wound healing;GO:0035313//wound healing, spreading of epidermal cells;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0048015//phosphatidylinositol-mediated signaling;GO:0008284//positive regulation of cell proliferation","K08523//heparin-binding EGF-like growth factor","NP_001936.1//proheparin-binding EGF-like growth factor precursor [Homo sapiens]","2//1"]
[9914,3206,0.11,0.16,0.540568381362703,0.665811910331681,"*",0.546646,"ATP2C2","GO:0031410//cytoplasmic vesicle;GO:0009898//cytoplasmic side of plasma membrane;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm;GO:0000139//Golgi membrane","GO:0046872//metal ion binding;GO:0005524//ATP binding;GO:0005388//calcium-transporting ATPase activity","GO:0090280//positive regulation of calcium ion import;GO:0061180//mammary gland epithelium development;GO:0072659//protein localization to plasma membrane;GO:0034220//ion transmembrane transport","K01537//Ca2+-transporting ATPase [EC:3.6.3.8]","NP_055676.3//calcium-transporting ATPase type 2C member 2 isoform 2 [Homo sapiens];NP_001278383.1//calcium-transporting ATPase type 2C member 2 isoform 3 [Homo sapiens];NP_001273456.2//calcium-transporting ATPase type 2C member 2 isoform 1 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[2022,2817,0.22,0.32,0.540568381362703,0.557608076369001,"*",0.402236,"ENG","GO:0005615//extracellular space;GO:0072563//endothelial microparticle;GO:0009986//cell surface;GO:0009897//external side of plasma membrane;GO:0016021//integral component of membrane","GO:0048185//activin binding;GO:0005114//type II transforming growth factor beta receptor binding;GO:0005539//glycosaminoglycan binding;GO:0050431//transforming growth factor beta binding;GO:0042803//protein homodimerization activity;GO:0005534//galactose binding","GO:0003222//ventricular trabecula myocardium morphogenesis;GO:0003148//outflow tract septum morphogenesis;GO:0097084//vascular smooth muscle cell development;GO:0003198//epithelial to mesenchymal transition involved in endocardial cushion formation;GO:0071260//cellular response to mechanical stimulus;GO:0048745//smooth muscle tissue development;GO:0010629//negative regulation of gene expression;GO:0032967//positive regulation of collagen biosynthetic process;GO:0017015//regulation of transforming growth factor beta receptor signaling pathway;GO:0071559//response to transforming growth factor beta;GO:1905065//positive regulation of vascular smooth muscle cell differentiation;GO:0001934//positive regulation of protein phosphorylation;GO:1905007//positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation;GO:0045766//positive regulation of angiogenesis;GO:0001570//vasculogenesis;GO:0060348//bone development;GO:0042493//response to drug;GO:0035912//dorsal aorta morphogenesis;GO:0030509//BMP signaling pathway;GO:0031960//response to corticosteroid;GO:0055009//atrial cardiac muscle tissue morphogenesis;GO:0001947//heart looping;GO:1905222//atrioventricular canal morphogenesis;GO:0003273//cell migration involved in endocardial cushion formation;GO:0048844//artery morphogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0070278//extracellular matrix constituent secretion;GO:0048845//venous blood vessel morphogenesis;GO:0001569//branching involved in blood vessel morphogenesis;GO:0001300//chronological cell aging","K06526//endoglin","BAF83078.1//unnamed protein product [Homo sapiens];XP_011709764.1//PREDICTED: endoglin [Macaca nemestrina]","1//3;3//A2MP1;2//1"]
[9899,12052,0.55,0.8,0.540568381362703,0.0135909559413203,"*",4.87178E-3,"SV2B","GO:0016020//membrane;GO:0030672//synaptic vesicle membrane;GO:0008021//synaptic vesicle;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0001669//acrosomal vesicle;GO:0005886//plasma membrane","GO:0022857//transmembrane transporter activity","GO:0006836//neurotransmitter transport","K06258//MFS transporter, VNT family, synaptic vesicle glycoprotein 2","XP_020009993.1//synaptic vesicle glycoprotein 2B isoform X2 [Castor canadensis];XP_006905404.1//PREDICTED: synaptic vesicle glycoprotein 2B [Pteropus alecto];NP_055663.1//synaptic vesicle glycoprotein 2B isoform 1 [Homo sapiens];NP_001309962.1//synaptic vesicle glycoprotein 2B isoform 3 [Homo sapiens];NP_001309965.1//synaptic vesicle glycoprotein 2B isoform 5 [Homo sapiens]","6;2//1"]
[9572,2793,8.48,12.33,0.54003662983964,{"v":2.6722236104446e-06,"d":"2.67E-06"},"*",{"v":4.74088e-07,"d":"4.74E-07"},"NR1D1","GO:0030425//dendrite;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0043197//dendritic spine;GO:0000790//nuclear chromatin;GO:0005737//cytoplasm","GO:0003707//steroid hormone receptor activity;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0020037//heme binding;GO:0003714//transcription corepressor activity;GO:0001046//core promoter sequence-specific DNA binding;GO:0001222//transcription corepressor binding;GO:0044212//transcription regulatory region DNA binding;GO:0004879//nuclear receptor activity;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0008270//zinc ion binding;GO:0003700//DNA binding transcription factor activity","GO:0071222//cellular response to lipopolysaccharide;GO:0061469//regulation of type B pancreatic cell proliferation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0044321//response to leptin;GO:0060086//circadian temperature homeostasis;GO:0061178//regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0019216//regulation of lipid metabolic process;GO:0032922//circadian regulation of gene expression;GO:0010498//proteasomal protein catabolic process;GO:0007623//circadian rhythm;GO:0045892//negative regulation of transcription, DNA-templated;GO:0030154//cell differentiation;GO:0045598//regulation of fat cell differentiation;GO:0034144//negative regulation of toll-like receptor 4 signaling pathway;GO:0006351//transcription, DNA-templated;GO:0070859//positive regulation of bile acid biosynthetic process;GO:0042752//regulation of circadian rhythm;GO:0005978//glycogen biosynthetic process;GO:0010871//negative regulation of receptor biosynthetic process;GO:0035947//regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:2000188//regulation of cholesterol homeostasis","K03728//nuclear receptor subfamily 1 group D member 1","NP_068370.1//nuclear receptor subfamily 1 group D member 1 [Homo sapiens]",4]
[25796,1043,55.78,81.06,0.539242241018529,{"v":1.08514545681818E-13,"d":"1.09E-13"},"*",{"v":8.36922e-15,"d":"8.37E-15"},"PGLS","GO:0070062//extracellular exosome;GO:0016021//integral component of membrane","GO:0017057//6-phosphogluconolactonase activity","GO:0006098//pentose-phosphate shunt;GO:0005975//carbohydrate metabolic process","K01057//6-phosphogluconolactonase [EC:3.1.1.31]","XP_003275860.2//PREDICTED: 6-phosphogluconolactonase [Nomascus leucogenys]","2//1"]
[29781,3070,16.76,24.35,0.538899623270353,{"v":5.0945355624355E-17,"d":"5.09E-17"},"*",{"v":3.0904e-18,"d":"3.09E-18"},"NCAPH2","GO:0016020//membrane;GO:0045171//intercellular bridge;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0030054//cell junction;GO:0005694//chromosome","NA","GO:0030261//chromosome condensation","K11490//condensin-2 complex subunit H2","NP_001171940.1//condensin-2 complex subunit H2 isoform 3 [Homo sapiens];NP_689512.2//condensin-2 complex subunit H2 isoform 2 [Homo sapiens];NP_055366.3//condensin-2 complex subunit H2 isoform 1 [Homo sapiens]","1//3;4;3//A2MP1"]
[7746,1683,1.77,2.57,0.53801899911088,0.175092479451725,"*",0.0911634,"ZSCAN9","NA","NA","NA","K09229//KRAB and SCAN domains-containing zinc finger protein;K09230//SCAN domain-containing zinc finger protein","XP_001373597.1//PREDICTED: zinc finger protein with KRAB and SCAN domains 8 isoform X1 [Monodelphis domestica];XP_014589763.1//PREDICTED: zinc finger and SCAN domain-containing protein 23 isoform X2 [Equus caballus]","4;1//3"]
[5176,1337,0.93,1.35,0.5376567859428,0.735413253012048,"*",0.62285,"SERPINF1","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0043203//axon hillock;GO:0005576//extracellular region;GO:0042470//melanosome;GO:0048471//perinuclear region of cytoplasm;GO:0005604//basement membrane","GO:0004867//serine-type endopeptidase inhibitor activity","GO:0060041//retina development in camera-type eye;GO:1901215//negative regulation of neuron death;GO:0001822//kidney development;GO:0010629//negative regulation of gene expression;GO:0050728//negative regulation of inflammatory response;GO:0008283//cell proliferation;GO:0046685//response to arsenic-containing substance;GO:0007614//short-term memory;GO:0042698//ovulation cycle;GO:0016525//negative regulation of angiogenesis;GO:0010596//negative regulation of endothelial cell migration;GO:0010976//positive regulation of neuron projection development;GO:0071279//cellular response to cobalt ion;GO:0007568//aging;GO:0071549//cellular response to dexamethasone stimulus;GO:0071300//cellular response to retinoic acid;GO:0071333//cellular response to glucose stimulus;GO:0050769//positive regulation of neurogenesis;GO:0010447//response to acidic pH;GO:0007275//multicellular organism development;GO:0060770//negative regulation of epithelial cell proliferation involved in prostate gland development","K19614//pigment epithelium-derived factor","XP_008968201.1//PREDICTED: pigment epithelium-derived factor isoform X1 [Pan paniscus];NP_002606.3//pigment epithelium-derived factor isoform 1 precursor [Homo sapiens];AAA93524.1//EPC-1 [Homo sapiens]","6;1//3"]
[440567,538,0.82,1.19,0.53726575868986,0.695478391873589,"*",0.578622,"UQCRHL","GO:0005750//mitochondrial respiratory chain complex III;GO:0005743//mitochondrial inner membrane;GO:0070469//respiratory chain","GO:0008121//ubiquinol-cytochrome-c reductase activity","GO:0009060//aerobic respiration;GO:0006122//mitochondrial electron transport, ubiquinol to cytochrome c","K00416//ubiquinol-cytochrome c reductase subunit 6","XP_003990099.1//PREDICTED: cytochrome b-c1 complex subunit 6, mitochondrial isoform X1 [Felis catus]","1//3"]
[11152,1898,22.85,33.16,0.537249841550318,{"v":1.02677589122807e-10,"d":"1.03E-10"},"*",{"v":1.025876E-11,"d":"1.03E-11"},"WDR45","GO:0019898//extrinsic component of membrane;GO:0005829//cytosol;GO:0034045//phagophore assembly site membrane","GO:0080025//phosphatidylinositol-3,5-bisphosphate binding;GO:0032266//phosphatidylinositol-3-phosphate binding","GO:0034497//protein localization to phagophore assembly site;GO:0006497//protein lipidation;GO:0044804//autophagy of nucleus;GO:0006914//autophagy;GO:0000422//autophagy of mitochondrion","K14810//ATP-dependent RNA helicase DDX56/DBP9 [EC:3.6.4.13];K17908//autophagy-related protein 18","XP_012912999.1//PREDICTED: WD repeat domain phosphoinositide-interacting protein 4 isoform X2 [Mustela putorius furo];XP_004755137.1//PREDICTED: WD repeat domain phosphoinositide-interacting protein 4 isoform X1 [Mustela putorius furo]","1//3;3//A2MP1"]
[4780,2751,42.22,61.25,0.536783265430139,{"v":2.20692693771626E-24,"d":"2.21E-24"},"*",{"v":7.9855e-26,"d":"7.99E-26"},"NFE2L2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000785//chromatin;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0032993//protein-DNA complex;GO:0005886//plasma membrane","GO:0003677//DNA binding;GO:0001205//transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0019904//protein domain specific binding;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0001102//RNA polymerase II activating transcription factor binding","GO:0035690//cellular response to drug;GO:0010499//proteasomal ubiquitin-independent protein catabolic process;GO:1904385//cellular response to angiotensin;GO:0016567//protein ubiquitination;GO:0071356//cellular response to tumor necrosis factor;GO:1902037//negative regulation of hematopoietic stem cell differentiation;GO:0042149//cellular response to glucose starvation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045454//cell redox homeostasis;GO:0071499//cellular response to laminar fluid shear stress;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0046326//positive regulation of glucose import;GO:1903788//positive regulation of glutathione biosynthetic process;GO:0070301//cellular response to hydrogen peroxide;GO:1902176//negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0045995//regulation of embryonic development;GO:0006351//transcription, DNA-templated;GO:0036003//positive regulation of transcription from RNA polymerase II promoter in response to stress;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:0007568//aging;GO:0006954//inflammatory response;GO:0046223//aflatoxin catabolic process;GO:1903206//negative regulation of hydrogen peroxide-induced cell death;GO:2000121//regulation of removal of superoxide radicals;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0034599//cellular response to oxidative stress;GO:0036499//PERK-mediated unfolded protein response;GO:0030194//positive regulation of blood coagulation","K05638//nuclear factor erythroid 2-related factor 2","NP_001300832.1//nuclear factor erythroid 2-related factor 2 isoform 5 [Homo sapiens];NP_001300831.1//nuclear factor erythroid 2-related factor 2 isoform 4 [Homo sapiens];XP_001145876.2//PREDICTED: nuclear factor erythroid 2-related factor 2 isoform X1 [Pan troglodytes];BAD92023.1//nuclear factor (erythroid-derived 2)-like 2 variant, partial [Homo sapiens];NP_001300833.1//nuclear factor erythroid 2-related factor 2 isoform 6 [Homo sapiens];NP_006155.2//nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens]","4;1//3;3//A2MP1"]
[148022,2727,8.95,12.98,0.53633079584752,{"v":2.20445773801002E-6,"d":"2.20E-06"},"*",{"v":3.8558e-07,"d":"3.86E-07"},"TICAM1","GO:0010008//endosome membrane;GO:0005829//cytosol;GO:0097342//ripoptosome;GO:0005776//autophagosome","GO:0004871//signal transducer activity;GO:0019901//protein kinase binding","GO:0032755//positive regulation of interleukin-6 production;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0097190//apoptotic signaling pathway;GO:0071222//cellular response to lipopolysaccharide;GO:0043330//response to exogenous dsRNA;GO:0032092//positive regulation of protein binding;GO:0030890//positive regulation of B cell proliferation;GO:0032760//positive regulation of tumor necrosis factor production;GO:0032816//positive regulation of natural killer cell activation;GO:0043496//regulation of protein homodimerization activity;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0002281//macrophage activation involved in immune response;GO:0045087//innate immune response;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0140052//cellular response to oxidised low-density lipoprotein particle stimulus;GO:0031398//positive regulation of protein ubiquitination;GO:0051607//defense response to virus;GO:0010508//positive regulation of autophagy;GO:0010628//positive regulation of gene expression;GO:0006954//inflammatory response;GO:0034128//negative regulation of MyD88-independent toll-like receptor signaling pathway;GO:0045359//positive regulation of interferon-beta biosynthetic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0045080//positive regulation of chemokine biosynthetic process;GO:0070266//necroptotic process;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:1900017//positive regulation of cytokine production involved in inflammatory response","K05842//toll-like receptor adapter molecule 1","NP_891549.1//TIR domain-containing adapter molecule 1 [Homo sapiens]","3//A2MP1"]
[57820,1366,16.39,23.77,0.536326048842976,{"v":7.24392961021655e-05,"d":"7.24E-05"},"*",{"v":1.633444E-5,"d":"1.63E-05"},"CCNB1IP1","GO:0000795//synaptonemal complex","GO:0061630//ubiquitin protein ligase activity","GO:0007131//reciprocal meiotic recombination;GO:0016567//protein ubiquitination;GO:0007286//spermatid development;GO:0051026//chiasma assembly;GO:0001825//blastocyst formation","K10639//E3 ubiquitin-protein ligase CCNP1IP1 [EC:2.3.2.27]","XP_003811770.1//PREDICTED: E3 ubiquitin-protein ligase CCNB1IP1 isoform X1 [Pan paniscus];XP_002824548.1//PREDICTED: E3 ubiquitin-protein ligase CCNB1IP1 [Pongo abelii]","4;3//A2MP1;2//1"]
[9076,3452,21.06,30.53,0.535722153181063,{"v":3.02248615595363E-17,"d":"3.02E-17"},"*",{"v":1.79563e-18,"d":"1.80E-18"},"CLDN1","GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0005737//cytoplasm;GO:0005887//integral component of plasma membrane;GO:0005923//bicellular tight junction;GO:0016021//integral component of membrane;GO:0016328//lateral plasma membrane;GO:0005886//plasma membrane","GO:0042802//identical protein binding;GO:0005198//structural molecule activity;GO:0001618//virus receptor activity","GO:0097421//liver regeneration;GO:0008065//establishment of blood-nerve barrier;GO:0032496//response to lipopolysaccharide;GO:0051260//protein homooligomerization;GO:0071356//cellular response to tumor necrosis factor;GO:0009636//response to toxic substance;GO:0045471//response to ethanol;GO:0070673//response to interleukin-18;GO:0045216//cell-cell junction organization;GO:0071346//cellular response to interferon-gamma;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;GO:0071548//response to dexamethasone;GO:0051291//protein heterooligomerization;GO:0090557//establishment of endothelial intestinal barrier;GO:0042538//hyperosmotic salinity response;GO:0007568//aging;GO:0071284//cellular response to lead ion;GO:1903348//positive regulation of bicellular tight junction assembly;GO:0070830//bicellular tight junction assembly;GO:0061772//drug transport across blood-nerve barrier;GO:0061436//establishment of skin barrier;GO:1903545//cellular response to butyrate","K06087//claudin","NP_066924.1//claudin-1 [Homo sapiens]",4]
[6672,3153,6.39,9.26,0.535196262313242,0.0053684702816413,"*",0.001744568,"SP100","GO:0016605//PML body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000784//nuclear chromosome, telomeric region;GO:0005737//cytoplasm;GO:0034399//nuclear periphery;GO:0005730//nucleolus;GO:0016604//nuclear body","GO:0070087//chromo shadow domain binding;GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0019904//protein domain specific binding;GO:0003713//transcription coactivator activity;GO:0019900//kinase binding;GO:0008134//transcription factor binding","GO:0060337//type I interferon signaling pathway;GO:0034097//response to cytokine;GO:0043433//negative regulation of DNA binding transcription factor activity;GO:0045185//maintenance of protein location;GO:0045893//positive regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0034340//response to type I interferon;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0034341//response to interferon-gamma;GO:0032897//negative regulation of viral transcription;GO:0046826//negative regulation of protein export from nucleus;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0010596//negative regulation of endothelial cell migration;GO:0048384//retinoic acid receptor signaling pathway;GO:0006351//transcription, DNA-templated;GO:0016032//viral process;GO:0032526//response to retinoic acid;GO:1902044//regulation of Fas signaling pathway;GO:1902041//regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0043392//negative regulation of DNA binding;GO:0045765//regulation of angiogenesis;GO:0000723//telomere maintenance;GO:0051271//negative regulation of cellular component movement;GO:0006978//DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator","K15413//nuclear autoantigen Sp-100","NP_001193632.1//nuclear autoantigen Sp-100 isoform 5 [Homo sapiens];NP_001193630.1//nuclear autoantigen Sp-100 isoform 3 [Homo sapiens];NP_001193633.1//nuclear autoantigen Sp-100 isoform 6 [Homo sapiens];NP_003104.2//nuclear autoantigen Sp-100 isoform 2 [Homo sapiens];NP_001193631.1//nuclear autoantigen Sp-100 isoform 4 [Homo sapiens];NP_001073860.1//nuclear autoantigen Sp-100 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[23208,5298,0.49,0.71,0.535037275389474,0.215971427912341,"*",0.11722,"SYT11","GO:0060076//excitatory synapse;GO:0032009//early phagosome;GO:0030054//cell junction;GO:0048787//presynaptic active zone membrane;GO:0045335//phagocytic vesicle;GO:0005887//integral component of plasma membrane;GO:0030672//synaptic vesicle membrane;GO:0016021//integral component of membrane;GO:0043197//dendritic spine;GO:0055037//recycling endosome;GO:0005886//plasma membrane;GO:0030424//axon;GO:0008021//synaptic vesicle;GO:0098793//presynapse;GO:0005764//lysosome;GO:0043195//terminal bouton;GO:0001891//phagocytic cup;GO:0014069//postsynaptic density;GO:0043005//neuron projection;GO:0048471//perinuclear region of cytoplasm;GO:0044297//cell body;GO:0060077//inhibitory synapse","GO:0000149//SNARE binding;GO:0046872//metal ion binding;GO:0030276//clathrin binding;GO:0048487//beta-tubulin binding;GO:0031625//ubiquitin protein ligase binding;GO:0019905//syntaxin binding;GO:0031369//translation initiation factor binding;GO:0042803//protein homodimerization activity","GO:1905469//negative regulation of clathrin-coated pit assembly;GO:1900424//regulation of defense response to bacterium;GO:0051289//protein homotetramerization;GO:0048791//calcium ion-regulated exocytosis of neurotransmitter;GO:1905154//negative regulation of membrane invagination;GO:1900165//negative regulation of interleukin-6 secretion;GO:1905162//regulation of phagosome maturation;GO:0001778//plasma membrane repair;GO:0006906//vesicle fusion;GO:1990927//calcium ion regulated lysosome exocytosis;GO:1904468//negative regulation of tumor necrosis factor secretion;GO:1905171//positive regulation of protein localization to phagocytic vesicle;GO:0050765//negative regulation of phagocytosis;GO:1900243//negative regulation of synaptic vesicle endocytosis;GO:0046929//negative regulation of neurotransmitter secretion","K19911//synaptotagmin-11","NP_689493.3//synaptotagmin-11 [Homo sapiens]",4]
[5905,3973,45.31,65.65,0.53496552026686,{"v":2.56884183414634e-41,"d":"2.57E-41"},"*",{"v":4.61536e-43,"d":"4.62E-43"},"RANGAP1","NA","GO:0005096//GTPase activator activity","GO:0007165//signal transduction","K14319//Ran GTPase-activating protein 1","XP_003989375.2//PREDICTED: ran GTPase-activating protein 1 isoform X1 [Felis catus]","1//3;3//A2MP1"]
[79641,1776,12.02,17.41,0.534479306939916,{"v":1.28833275658521E-5,"d":"1.29E-05"},"*",{"v":2.54134E-6,"d":"2.54E-06"},"ROGDI","GO:0005635//nuclear envelope;GO:0005622//intracellular","NA","GO:0022008//neurogenesis;GO:0030097//hemopoiesis;GO:0007420//brain development;GO:0008284//positive regulation of cell proliferation;GO:0042475//odontogenesis of dentin-containing tooth","K03006//DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6];K16938//septin 3/9/12;K22022//mucin-21;K17925//sorting nexin-13;K05748//WAS protein family, member 2","NP_078865.1//protein rogdi homolog [Homo sapiens]","2//1"]
[5950,908,7.36,10.66,0.534429766702163,0.0261172836175711,"*",0.01012384,"RBP4","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0043234//protein complex;GO:0005829//cytosol;GO:0005576//extracellular region","GO:0034632//retinol transmembrane transporter activity;GO:0016918//retinal binding;GO:0046982//protein heterodimerization activity;GO:0036094//small molecule binding;GO:0005501//retinoid binding;GO:0005215//transporter activity;GO:0019841//retinol binding","GO:0060044//negative regulation of cardiac muscle cell proliferation;GO:0030324//lung development;GO:0032024//positive regulation of insulin secretion;GO:0060068//vagina development;GO:0060065//uterus development;GO:0048738//cardiac muscle tissue development;GO:0007601//visual perception;GO:0045471//response to ethanol;GO:0042593//glucose homeostasis;GO:0034633//retinol transport;GO:0051024//positive regulation of immunoglobulin secretion;GO:0030277//maintenance of gastrointestinal epithelium;GO:0048807//female genitalia morphogenesis;GO:0001654//eye development;GO:0042572//retinol metabolic process;GO:0006094//gluconeogenesis;GO:0007507//heart development;GO:0048562//embryonic organ morphogenesis;GO:0032526//response to retinoic acid;GO:0060059//embryonic retina morphogenesis in camera-type eye;GO:0001523//retinoid metabolic process;GO:0048706//embryonic skeletal system development;GO:0060347//heart trabecula formation;GO:0060157//urinary bladder development","K18271//retinol-binding protein 4","XP_007961780.1//PREDICTED: retinol-binding protein 4 isoform X1 [Chlorocebus sabaeus];NP_001310447.1//retinol-binding protein 4 isoform b [Homo sapiens]","1//3;3//A2MP1"]
[51257,1570,10.61,15.36,0.533753559806391,0.000313327198512643,"*",{"v":7.91262e-05,"d":"7.91E-05"},"2019-03-02","GO:0005765//lysosomal membrane;GO:0010008//endosome membrane;GO:0005783//endoplasmic reticulum;GO:0031410//cytoplasmic vesicle;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0008270//zinc ion binding;GO:0004842//ubiquitin-protein transferase activity","GO:0016567//protein ubiquitination;GO:0006897//endocytosis","K10657//E3 ubiquitin-protein ligase MARCH2 [EC:2.3.2.27]","XP_012646263.1//E3 ubiquitin-protein ligase MARCH2 isoform X1 [Microcebus murinus];XP_016018568.1//PREDICTED: E3 ubiquitin-protein ligase MARCH2 isoform X10 [Rousettus aegyptiacus]","1//3;4"]
[26232,1724,4.49,6.5,0.53372427317467,0.0133848598810773,"*",0.0047912,"FBXO2","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0043197//dendritic spine;GO:0019005//SCF ubiquitin ligase complex","GO:0030246//carbohydrate binding;GO:0001540//amyloid-beta binding","GO:0031396//regulation of protein ubiquitination;GO:0006516//glycoprotein catabolic process;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination","K10099//F-box protein 2","XP_004596100.1//PREDICTED: F-box only protein 2 isoform X2 [Ochotona princeps]",5]
[5936,1576,106.18,153.67,0.533323497923029,{"v":1.74967141741425E-33,"d":"1.75E-33"},"*",{"v":4.15128e-35,"d":"4.15E-35"},"RBM4","GO:0010494//cytoplasmic stress granule;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0097157//pre-mRNA intronic binding;GO:0003730//mRNA 3'-UTR binding;GO:0036002//pre-mRNA binding;GO:0097158//pre-mRNA intronic pyrimidine-rich binding;GO:0035198//miRNA binding;GO:0008270//zinc ion binding;GO:0030332//cyclin binding","GO:0006396//RNA processing;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0002192//IRES-dependent translational initiation of linear mRNA;GO:0045947//negative regulation of translational initiation;GO:0097167//circadian regulation of translation;GO:0017148//negative regulation of translation;GO:0046685//response to arsenic-containing substance;GO:0043153//entrainment of circadian clock by photoperiod;GO:0006397//mRNA processing;GO:0030154//cell differentiation;GO:0046822//regulation of nucleocytoplasmic transport;GO:0002190//cap-independent translational initiation;GO:0051149//positive regulation of muscle cell differentiation;GO:0032055//negative regulation of translation in response to stress;GO:0008380//RNA splicing;GO:0035278//miRNA mediated inhibition of translation","K13187//RNA-binding protein 4","EPQ06579.1//RNA-binding protein 14 [Myotis brandtii];XP_021541240.1//RNA-binding protein 4 isoform X2 [Neomonachus schauinslandi];NP_001185773.1//RNA-binding protein 4 isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[55168,1207,33.74,48.83,0.533307804349898,{"v":1.0842692278453e-09,"d":"1.08E-09"},"*",{"v":1.228576e-10,"d":"1.23E-10"},"MRPS18A","GO:0005763//mitochondrial small ribosomal subunit;GO:0005743//mitochondrial inner membrane;GO:0022627//cytosolic small ribosomal subunit","GO:0003735//structural constituent of ribosome","GO:0032543//mitochondrial translation;GO:0006412//translation;GO:0070126//mitochondrial translational termination;GO:0070125//mitochondrial translational elongation","K02963//small subunit ribosomal protein S18","XP_007458338.1//PREDICTED: 28S ribosomal protein S18a, mitochondrial isoform X2 [Lipotes vexillifer];NP_060605.1//39S ribosomal protein S18a, mitochondrial isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[27201,4262,0.47,0.68,0.532873989572702,0.276758740425532,"*",0.1596032,"GPR78","GO:0005622//intracellular;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004930//G-protein coupled receptor activity","GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway","K08418//G protein-coupled receptor 78","NP_543009.2//G-protein coupled receptor 78 [Homo sapiens]",4]
[84063,2860,0.56,0.81,0.532495080827021,0.332738486475239,"*",0.200218,"KIRREL2","GO:0016021//integral component of membrane;GO:0036057//slit diaphragm;GO:0005886//plasma membrane","NA","GO:0098609//cell-cell adhesion;GO:0007155//cell adhesion;GO:0001933//negative regulation of protein phosphorylation","K17341//hemicentin;K18273//alpha-tectorin","NP_954648.3//kin of IRRE-like protein 2 isoform b precursor [Homo sapiens];NP_001316459.1//kin of IRRE-like protein 2 isoform d precursor [Homo sapiens];XP_004089244.1//PREDICTED: kin of IRRE-like protein 2 isoform X1 [Nomascus leucogenys];NP_115499.5//kin of IRRE-like protein 2 isoform a precursor [Homo sapiens]","6;1//3;3//A2MP1"]
[4647,7339,0.65,0.94,0.532221038649183,0.0626758339167862,"*",0.0273476,"MYO7A","GO:0005765//lysosomal membrane;GO:0001917//photoreceptor inner segment;GO:0005938//cell cortex;GO:0016324//apical plasma membrane;GO:0032391//photoreceptor connecting cilium;GO:1990435//upper tip-link density;GO:0042470//melanosome;GO:0001750//photoreceptor outer segment;GO:0005902//microvillus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0032420//stereocilium;GO:0031477//myosin VII complex;GO:0045202//synapse","GO:0051015//actin filament binding;GO:0005524//ATP binding;GO:0047485//protein N-terminus binding;GO:0042803//protein homodimerization activity;GO:0043531//ADP binding;GO:0019904//protein domain specific binding;GO:0000146//microfilament motor activity;GO:0005516//calmodulin binding;GO:0030898//actin-dependent ATPase activity;GO:0030507//spectrin binding","GO:0030048//actin filament-based movement;GO:0060088//auditory receptor cell stereocilium organization;GO:0007601//visual perception;GO:0006886//intracellular protein transport;GO:0050957//equilibrioception;GO:0001845//phagolysosome assembly;GO:0007605//sensory perception of sound;GO:0050953//sensory perception of light stimulus;GO:0051904//pigment granule transport;GO:0048563//post-embryonic animal organ morphogenesis;GO:0042462//eye photoreceptor cell development;GO:0007040//lysosome organization","K10359//myosin VIIa","NP_001120652.1//unconventional myosin-VIIa isoform 2 [Homo sapiens];NP_000251.3//unconventional myosin-VIIa isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[11217,6815,4.73,6.84,0.532156141546503,{"v":5.86873910813226e-08,"d":"5.87E-08"},"*",{"v":8.22226e-09,"d":"8.22E-09"},"AKAP2","NA","NA","NA","K16519//A-kinase anchor protein 2","NP_001004065.2//A-kinase anchor protein 2 isoform 1 [Homo sapiens];NP_001185585.1//A-kinase anchor protein 2 isoform 3 [Homo sapiens];NP_671492.1//PALM2-AKAP2 protein isoform 2 [Homo sapiens]","1//3;4;2//1"]
[8336,487,0.74,1.07,0.532013620772197,0.665913460230306,"*",0.546646,"HIST1H2AM","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0000786//nucleosome","GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity;GO:0019899//enzyme binding","GO:0006342//chromatin silencing;GO:0006334//nucleosome assembly;GO:0006352//DNA-templated transcription, initiation","K11251//histone H2A;K11254//histone H4","XP_011931511.1//PREDICTED: uncharacterized protein LOC105593202 [Cercocebus atys]","2//1"]
[10616,1964,106.83,154.47,0.532009834434394,{"v":1.80210114992126E-77,"d":"1.80E-77"},"*",{"v":1.432746e-79,"d":"1.43E-79"},"RBCK1","GO:0071797//LUBAC complex;GO:0005829//cytosol","GO:0043130//ubiquitin binding;GO:0046872//metal ion binding;GO:0004842//ubiquitin-protein transferase activity","GO:0050852//T cell receptor signaling pathway;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0060546//negative regulation of necroptotic process;GO:0016032//viral process;GO:0010803//regulation of tumor necrosis factor-mediated signaling pathway;GO:0042346//positive regulation of NF-kappaB import into nucleus;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0000209//protein polyubiquitination;GO:0097039//protein linear polyubiquitination","K10630//RanBP-type and C3HC4-type zinc finger-containing protein 1 [EC:2.3.2.27]","NP_006453.1//ranBP-type and C3HC4-type zinc finger-containing protein 1 isoform 1 [Homo sapiens];NP_001310885.1//ranBP-type and C3HC4-type zinc finger-containing protein 1 isoform 3 [Homo sapiens];NP_112506.2//ranBP-type and C3HC4-type zinc finger-containing protein 1 isoform 2 [Homo sapiens];XP_017800410.1//ranBP-type and C3HC4-type zinc finger-containing protein 1 isoform X5 [Papio anubis]","1//3;3//A2MP1;5"]
[8530,940,0.18,0.26,0.53051471669878,0.782367726,"*",0.685686,"CST7","NA","GO:0004869//cysteine-type endopeptidase inhibitor activity","NA","K13903//cystatin-F","BAA34941.1//human CMAP [Homo sapiens]","3//A2MP1"]
[1803,3913,0.18,0.26,0.53051471669878,0.557511311409978,"*",0.402236,"DPP4","GO:0016020//membrane;GO:0005765//lysosomal membrane;GO:0070062//extracellular exosome;GO:0005925//focal adhesion;GO:0016324//apical plasma membrane;GO:0046581//intercellular canaliculus;GO:0030027//lamellipodium;GO:0031258//lamellipodium membrane;GO:0071438//invadopodium membrane;GO:0009986//cell surface;GO:0045121//membrane raft;GO:0030139//endocytic vesicle;GO:0005576//extracellular region;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004252//serine-type endopeptidase activity;GO:0002020//protease binding;GO:0042802//identical protein binding;GO:0005102//receptor binding;GO:0042803//protein homodimerization activity;GO:0008236//serine-type peptidase activity;GO:0008239//dipeptidyl-peptidase activity;GO:0001618//virus receptor activity","GO:0042110//T cell activation;GO:0033632//regulation of cell-cell adhesion mediated by integrin;GO:0043542//endothelial cell migration;GO:0035641//locomotory exploration behavior;GO:0031295//T cell costimulation;GO:0001666//response to hypoxia;GO:0050796//regulation of insulin secretion;GO:0001662//behavioral fear response;GO:0007155//cell adhesion;GO:0010716//negative regulation of extracellular matrix disassembly;GO:0036343//psychomotor behavior;GO:0008284//positive regulation of cell proliferation","K01278//dipeptidyl-peptidase 4 [EC:3.4.14.5]","NP_001926.2//dipeptidyl peptidase 4 [Homo sapiens]","3//A2MP1"]
[220382,1875,0.09,0.13,0.53051471669878,0.7806948085531,"*",0.685686,"FAM181B","NA","NA","NA","K13172//serine/arginine repetitive matrix protein 2;K13171//serine/arginine repetitive matrix protein 1","NP_787081.2//protein FAM181B [Homo sapiens]","3//A2MP1"]
[10630,2818,0.09,0.13,0.53051471669878,0.81027169892172,"*",0.724446,"PDPN","GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0042995//cell projection;GO:0009897//external side of plasma membrane;GO:0016324//apical plasma membrane;GO:0097197//tetraspanin-enriched microdomain;GO:0071437//invadopodium;GO:0031410//cytoplasmic vesicle;GO:0030054//cell junction;GO:0032587//ruffle membrane;GO:0005887//integral component of plasma membrane;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0031527//filopodium membrane;GO:0030027//lamellipodium;GO:0030175//filopodium;GO:0001726//ruffle;GO:0031258//lamellipodium membrane;GO:0061851//leading edge of lamellipodium;GO:0045121//membrane raft;GO:0031528//microvillus membrane","GO:0019956//chemokine binding;GO:0005102//receptor binding;GO:0051087//chaperone binding","GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:0030324//lung development;GO:1904328//regulation of myofibroblast contraction;GO:0030335//positive regulation of cell migration;GO:0070252//actin-mediated cell contraction;GO:0030168//platelet activation;GO:0098609//cell-cell adhesion;GO:0060838//lymphatic endothelial cell fate commitment;GO:0008283//cell proliferation;GO:0051272//positive regulation of cellular component movement;GO:1905863//invadopodium organization;GO:1901731//positive regulation of platelet aggregation;GO:0044319//wound healing, spreading of cells;GO:0008285//negative regulation of cell proliferation;GO:0000902//cell morphogenesis;GO:0048535//lymph node development;GO:0043066//negative regulation of apoptotic process;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0008360//regulation of cell shape;GO:0090091//positive regulation of extracellular matrix disassembly;GO:1900024//regulation of substrate adhesion-dependent cell spreading;GO:0007266//Rho protein signal transduction;GO:0006693//prostaglandin metabolic process;GO:2000392//regulation of lamellipodium morphogenesis;GO:0048286//lung alveolus development;GO:0001946//lymphangiogenesis","K16778//podoplanin","NP_006465.3//podoplanin isoform a [Homo sapiens];NP_938203.2//podoplanin isoform b [Homo sapiens]","4;1//3;2//1"]
[11105,3284,0.27,0.39,0.53051471669878,0.495819749727965,"*",0.3423,"PRDM7","GO:0005634//nucleus;GO:0005694//chromosome","GO:0003676//nucleic acid binding;GO:0018024//histone-lysine N-methyltransferase activity","GO:0006355//regulation of transcription, DNA-templated","K20796//histone-lysine N-methyltransferase PRDM7/9 [EC:2.1.1.43]","NP_001091643.1//probable histone-lysine N-methyltransferase PRDM7 [Homo sapiens]","1//3"]
[375775,4780,0.45,0.65,0.53051471669878,0.247697899601064,"*",0.139929,"PNPLA7","GO:0005765//lysosomal membrane;GO:0031965//nuclear membrane;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane","GO:0004622//lysophospholipase activity","GO:0032502//developmental process;GO:0016042//lipid catabolic process","K14676//lysophospholipid hydrolase [EC:3.1.1.5]","NP_689499.4//patatin-like phospholipase domain-containing protein 7 isoform b [Homo sapiens];NP_001092007.2//patatin-like phospholipase domain-containing protein 7 isoform a [Homo sapiens]","4;2//1"]
[6274,738,69.91,100.92,0.529641371335296,{"v":1.39285466630435e-11,"d":"1.39E-11"},"*",{"v":1.283512E-12,"d":"1.28E-12"},"S100A3","NA","NA","NA","NA","XP_007975266.1//PREDICTED: protein S100-A3 isoform X1 [Chlorocebus sabaeus]","1//3"]
[1238,2978,0.97,1.4,0.529370174757839,0.169331357822142,"*",0.0876126,"ACKR2","GO:0043231//intracellular membrane-bounded organelle;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0005884//actin filament;GO:0005887//integral component of plasma membrane;GO:0005829//cytosol;GO:0055037//recycling endosome;GO:0005769//early endosome;GO:0005886//plasma membrane","GO:0005044//scavenger receptor activity;GO:0016493//C-C chemokine receptor activity;GO:0019957//C-C chemokine binding;GO:0004950//chemokine receptor activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0007275//multicellular organism development;GO:0006955//immune response;GO:0006935//chemotaxis;GO:0006954//inflammatory response","K04187//chemokine binding protein 2","XP_002813926.1//PREDICTED: atypical chemokine receptor 2 [Pongo abelii]",4]
[283643,1694,15.16,21.88,0.529342984621465,{"v":2.20661806940966e-06,"d":"2.21E-06"},"*",{"v":3.86096e-07,"d":"3.86E-07"},"TEDC1","NA","NA","NA","K22022//mucin-21;K19475//WAS/WASL-interacting protein;K19720//collagen, type III, alpha;K20638//Rho GTPase-activating protein 17","CAD62351.1//unnamed protein product, partial [Homo sapiens];CAD62611.1//unnamed protein product, partial [Homo sapiens];NP_001128347.1//uncharacterized protein C14orf80 isoform 1 [Homo sapiens]","1//3"]
[64374,1908,11.42,16.47,0.528277904363512,{"v":1.61494848034935E-5,"d":"1.61E-05"},"*",{"v":3.24122e-06,"d":"3.24E-06"},"SIL1","GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum","GO:0051082//unfolded protein binding","GO:0006457//protein folding;GO:0006886//intracellular protein transport","K14001//nucleotide exchange factor SIL1","XP_011541872.1//PREDICTED: nucleotide exchange factor SIL1 isoform X1 [Homo sapiens]","1//3;4"]
[7425,2586,7.56,10.9,0.527869995443216,{"v":4.0037215132948e-05,"d":"4.00E-05"},"*",{"v":8.67214e-06,"d":"8.67E-06"},"VGF","GO:0043231//intracellular membrane-bounded organelle;GO:0005615//extracellular space;GO:0031410//cytoplasmic vesicle","GO:0005184//neuropeptide hormone activity;GO:0005179//hormone activity","GO:0032868//response to insulin;GO:0009409//response to cold;GO:0051591//response to cAMP;GO:0006091//generation of precursor metabolites and energy;GO:0002021//response to dietary excess;GO:0001541//ovarian follicle development;GO:0030073//insulin secretion;GO:0042593//glucose homeostasis;GO:0019953//sexual reproduction;GO:0033500//carbohydrate homeostasis;GO:0048167//regulation of synaptic plasticity","K19720//collagen, type III, alpha","XP_011758272.1//PREDICTED: LOW QUALITY PROTEIN: neurosecretory protein VGF [Macaca nemestrina]","3//A2MP1"]
[3399,1252,342.57,493.71,0.527265051555855,{"v":1.19480094867925E-92,"d":"1.19E-92"},"*",{"v":7.92844e-95,"d":"7.93E-95"},"ID3","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0046983//protein dimerization activity","GO:0045892//negative regulation of transcription, DNA-templated","K17694//DNA-binding protein inhibitor ID3","CAA47360.1//helix-loop-helix protein [Homo sapiens]",4]
[80194,928,29.52,42.53,0.526788133565368,{"v":1.2266034506885E-6,"d":"1.23E-06"},"*",{"v":2.06328e-07,"d":"2.06E-07"},"TMEM134","GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm","NA","NA","K22020//mucin-19","XP_007963790.1//PREDICTED: transmembrane protein 134 isoform X2 [Chlorocebus sabaeus];XP_007963728.1//PREDICTED: transmembrane protein 134 isoform X1 [Chlorocebus sabaeus]","3//A2MP1;2//1"]
[83853,974,0.59,0.85,0.52674788677586,0.512083012749147,"*",0.357054,"ROPN1L","GO:0031514//motile cilium;GO:0005737//cytoplasm","NA","GO:0001932//regulation of protein phosphorylation;GO:0030317//flagellated sperm motility;GO:0048240//sperm capacitation;GO:0003351//epithelial cilium movement","NA","NP_114122.2//ropporin-1-like protein [Homo sapiens]","1//3;4"]
[84993,1350,30.27,43.6,0.526439459836775,{"v":3.26762264705882e-09,"d":"3.27E-09"},"*",{"v":3.8948e-10,"d":"3.89E-10"},"UBL7","NA","NA","NA","K04523//ubiquilin","XP_003363698.2//PREDICTED: ubiquitin-like protein 7 isoform X1 [Equus caballus];NP_001273671.1//ubiquitin-like protein 7 isoform b [Homo sapiens];XP_009427813.2//PREDICTED: ubiquitin-like protein 7 isoform X1 [Pan troglodytes];KFO37988.1//Ubiquitin-like protein 7 [Fukomys damarensis];XP_008014084.1//PREDICTED: ubiquitin-like protein 7 isoform X4 [Chlorocebus sabaeus]","4;1//3"]
[4004,1008,2.68,3.86,0.526367846810308,0.209030882025081,"*",0.112694,"LMO1","GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0046872//metal ion binding","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:1902036//regulation of hematopoietic stem cell differentiation;GO:0046013//regulation of T cell homeostatic proliferation","K15612//rhombotin-2","AAH39512.1//LIM domain only 1 (rhombotin 1), partial [Homo sapiens];EFB17284.1//hypothetical protein PANDA_004271, partial [Ailuropoda melanoleuca]","1//3;2//1"]
[84065,1629,28.6,41.18,0.525928682966502,{"v":9.08715392443325e-11,"d":"9.09E-11"},"*",{"v":9.03368e-12,"d":"9.03E-12"},"TMEM222","GO:0016021//integral component of membrane","NA","NA","K20726//transmembrane protein 222","NP_115501.2//transmembrane protein 222 [Homo sapiens]","2//1"]
[51259,1295,9.49,13.66,0.525477491268981,0.00175874864689567,"*",0.000516042,"TMEM216","GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0036038//MKS complex","NA","GO:0060271//cilium assembly;GO:0097711//ciliary basal body-plasma membrane docking","K19385//transmembrane protein 216","XP_003274085.1//PREDICTED: transmembrane protein 216 isoform X1 [Nomascus leucogenys];XP_012351755.1//PREDICTED: transmembrane protein 216 isoform X2 [Nomascus leucogenys]","1//3;2//1;5"]
[403312,3421,0.66,0.95,0.525461488972494,0.256280829932871,"*",0.1457884,"LOC403312","NA","NA","NA","K15696//RING finger protein 113B;K01064//wingless-type MMTV integration site family, member 9","XP_011908665.1//PREDICTED: LOW QUALITY PROTEIN: putative uncharacterized protein MGC39545 [Cercocebus atys]","1//3"]
[9052,2856,41.41,59.59,0.525091044743758,{"v":2.77200090810811e-26,"d":"2.77E-26"},"*",{"v":8.98896e-28,"d":"8.99E-28"},"GPRC5A","GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0005730//nucleolus;GO:0005887//integral component of plasma membrane;GO:0031982//vesicle;GO:0005886//plasma membrane;GO:0030659//cytoplasmic vesicle membrane","GO:0004930//G-protein coupled receptor activity;GO:0045296//cadherin binding","GO:0007165//signal transduction;GO:0007175//negative regulation of epidermal growth factor-activated receptor activity","K08468//G protein-coupled receptor family C group 5 member A","NP_003970.1//retinoic acid-induced protein 3 [Homo sapiens]","3//A2MP1"]
[2954,1395,13.92,20.02,0.524282762987265,{"v":8.17300972499311e-05,"d":"8.17E-05"},"*",{"v":1.856758E-5,"d":"1.86E-05"},"GSTZ1","GO:0005829//cytosol;GO:0005739//mitochondrion","GO:0004364//glutathione transferase activity;GO:0016853//isomerase activity;GO:0042802//identical protein binding;GO:0004602//glutathione peroxidase activity;GO:0016740//transferase activity;GO:0016034//maleylacetoacetate isomerase activity;GO:0042803//protein homodimerization activity","GO:0009072//aromatic amino acid family metabolic process;GO:0006572//tyrosine catabolic process;GO:0006749//glutathione metabolic process;GO:0006559//L-phenylalanine catabolic process;GO:1901687//glutathione derivative biosynthetic process","K01800//maleylacetoacetate isomerase [EC:5.2.1.2]","NP_665877.1//maleylacetoacetate isomerase isoform 1 [Homo sapiens];NP_665878.2//maleylacetoacetate isomerase isoform 2 [Homo sapiens]","1//3;2//1"]
[8347,438,0.89,1.28,0.524266569033602,0.666218295872435,"*",0.546646,"HIST1H2BC","NA","NA","NA","K11252//histone H2B","EDL84564.1//histone 1, H2bn (predicted) [Rattus norvegicus]","2//1"]
[6158,1502,496.8,714.45,0.524167875864697,{"v":5.25246051448276e-147,"d":"5.25E-147"},"*",{"v":1.907116e-149,"d":"1.91E-149"},"RPL28","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0030425//dendrite;GO:0044297//cell body;GO:0005829//cytosol;GO:0022625//cytosolic large ribosomal subunit;GO:0036464//cytoplasmic ribonucleoprotein granule","GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome","GO:1903955//positive regulation of protein targeting to mitochondrion;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:1903146//regulation of autophagy of mitochondrion;GO:0006364//rRNA processing;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006413//translational initiation;GO:0006412//translation;GO:0019083//viral transcription","K02903//large subunit ribosomal protein L28e","XP_017502729.1//PREDICTED: 60S ribosomal protein L28 isoform X3 [Manis javanica];NP_001129606.1//60S ribosomal protein L28 isoform 1 [Homo sapiens];BAD92864.1//ribosomal protein L28 variant, partial [Homo sapiens];NP_001129607.1//60S ribosomal protein L28 isoform 3 [Homo sapiens]","4;1//3"]
[6648,3764,34.53,49.64,0.52365278127697,{"v":2.49578620440529e-50,"d":"2.50E-50"},"*",{"v":3.54666e-52,"d":"3.55E-52"},"SOD2","GO:0005759//mitochondrial matrix;GO:0070062//extracellular exosome;GO:0042645//mitochondrial nucleoid;GO:0043209//myelin sheath;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0004784//superoxide dismutase activity;GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0042802//identical protein binding;GO:0019825//oxygen binding;GO:0019899//enzyme binding;GO:0030145//manganese ion binding","GO:0006801//superoxide metabolic process;GO:0008217//regulation of blood pressure;GO:0000303//response to superoxide;GO:0030335//positive regulation of cell migration;GO:0034021//response to silicon dioxide;GO:0051260//protein homooligomerization;GO:0010332//response to gamma radiation;GO:0048666//neuron development;GO:0055072//iron ion homeostasis;GO:0022904//respiratory electron transport chain;GO:0009791//post-embryonic development;GO:0003032//detection of oxygen;GO:0071000//response to magnetism;GO:0033591//response to L-ascorbic acid;GO:0008285//negative regulation of cell proliferation;GO:0071361//cellular response to ethanol;GO:0019430//removal of superoxide radicals;GO:0042493//response to drug;GO:0051289//protein homotetramerization;GO:0007507//heart development;GO:0043524//negative regulation of neuron apoptotic process;GO:0010043//response to zinc ion;GO:0045599//negative regulation of fat cell differentiation;GO:0043066//negative regulation of apoptotic process;GO:0048147//negative regulation of fibroblast proliferation;GO:0035902//response to immobilization stress;GO:0001666//response to hypoxia;GO:0007005//mitochondrion organization;GO:0010042//response to manganese ion;GO:0046686//response to cadmium ion;GO:0006749//glutathione metabolic process;GO:0001315//age-dependent response to reactive oxygen species;GO:0034599//cellular response to oxidative stress;GO:0055093//response to hyperoxia;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0048773//erythrophore differentiation;GO:0032496//response to lipopolysaccharide;GO:0032364//oxygen homeostasis;GO:0051602//response to electrical stimulus;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0010269//response to selenium ion;GO:0042554//superoxide anion generation;GO:0030097//hemopoiesis;GO:0035722//interleukin-12-mediated signaling pathway;GO:0001836//release of cytochrome c from mitochondria;GO:1902176//negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0001889//liver development;GO:0009409//response to cold;GO:0048678//response to axon injury;GO:0014823//response to activity;GO:0008631//intrinsic apoptotic signaling pathway in response to oxidative stress;GO:0042542//response to hydrogen peroxide;GO:0050790//regulation of catalytic activity;GO:0035900//response to isolation stress;GO:0007626//locomotory behavior;GO:0051881//regulation of mitochondrial membrane potential;GO:0003069//acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure;GO:0001306//age-dependent response to oxidative stress;GO:0050665//hydrogen peroxide biosynthetic process","K04564//superoxide dismutase, Fe-Mn family [EC:1.15.1.1]","NP_001019637.1//superoxide dismutase [Mn], mitochondrial isoform B [Homo sapiens];NP_000627.2//superoxide dismutase [Mn], mitochondrial isoform A precursor [Homo sapiens];NP_001309744.1//superoxide dismutase [Mn], mitochondrial isoform C precursor [Homo sapiens];NP_001309745.1//superoxide dismutase [Mn], mitochondrial isoform D [Homo sapiens]","1//3;3//A2MP1;2//1"]
[648791,1745,0.32,0.46,0.523561956057013,0.634421781026749,"*",0.4781,"PPP1R3G","NA","NA","NA","K07189//protein phosphatase 1 regulatory subunit 3A/B/C/D/E","NP_001138587.1//protein phosphatase 1 regulatory subunit 3G [Homo sapiens]","2//1"]
[9071,2490,0.16,0.23,0.523561956057013,0.695426064855918,"*",0.578622,"CLDN10","GO:0016021//integral component of membrane;GO:0005923//bicellular tight junction;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0042802//identical protein binding;GO:0005198//structural molecule activity","GO:0007155//cell adhesion;GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;GO:0006811//ion transport","K06087//claudin","NP_008915.1//claudin-10 isoform b precursor [Homo sapiens];EAX08953.1//hCG2039317, partial [Homo sapiens]","4;1//3;3//A2MP1"]
[1496,3870,0.16,0.23,0.523561956057013,0.640977714514707,"*",0.500656,"CTNNA2","GO:0016323//basolateral plasma membrane;GO:0030424//axon;GO:0005634//nucleus;GO:0014069//postsynaptic density;GO:0030027//lamellipodium;GO:0005737//cytoplasm;GO:0005912//adherens junction;GO:0005913//cell-cell adherens junction;GO:0005829//cytosol;GO:0015629//actin cytoskeleton","GO:0051015//actin filament binding;GO:0042802//identical protein binding;GO:0005198//structural molecule activity;GO:0005200//structural constituent of cytoskeleton;GO:0045296//cadherin binding","GO:0048854//brain morphogenesis;GO:0051823//regulation of synapse structural plasticity;GO:0060134//prepulse inhibition;GO:0021942//radial glia guided migration of Purkinje cell;GO:0048813//dendrite morphogenesis;GO:0007409//axonogenesis;GO:0098609//cell-cell adhesion;GO:0007155//cell adhesion;GO:0051149//positive regulation of muscle cell differentiation","K05691//catenin alpha","XP_012503919.1//PREDICTED: catenin alpha-2 isoform X2 [Propithecus coquereli];NP_001269527.1//catenin alpha-2 isoform 4 [Homo sapiens];XP_012503918.1//PREDICTED: catenin alpha-2 isoform X1 [Propithecus coquereli];NP_001158355.1//catenin alpha-2 isoform 2 [Homo sapiens];NP_001269528.1//catenin alpha-2 isoform 5 [Homo sapiens];XP_004090482.2//PREDICTED: catenin alpha-2 isoform X1 [Nomascus leucogenys];XP_017392184.1//PREDICTED: catenin alpha-2 isoform X5 [Cebus capucinus imitator]","1//3;3//A2MP1;2//1"]
[10025,2952,10.36,14.89,0.523319750895546,{"v":2.10659540759282e-07,"d":"2.11E-07"},"*",{"v":3.16108E-8,"d":"3.16E-08"},"MED16","GO:0016020//membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016592//mediator complex","GO:0042809//vitamin D receptor binding;GO:0003713//transcription coactivator activity;GO:0046966//thyroid hormone receptor binding;GO:0004872//receptor activity;GO:0003712//transcription cofactor activity;GO:0003824//catalytic activity;GO:0030375//thyroid hormone receptor coactivator activity","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0030521//androgen receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated","K15159//mediator of RNA polymerase II transcription subunit 16","NP_005472.2//mediator of RNA polymerase II transcription subunit 16 [Homo sapiens]","2//1"]
[728888,3497,5.56,7.99,0.523110620204469,{"v":3.87959319918817e-05,"d":"3.88E-05"},"*",{"v":8.37656e-06,"d":"8.38E-06"},"NPIPB11","GO:0005654//nucleoplasm;GO:0016021//integral component of membrane","NA","NA","K09187//histone-lysine N-methyltransferase MLL2 [EC:2.1.1.43]","NP_001297066.1//nuclear pore complex-interacting protein family member B11 [Homo sapiens]","1//3"]
[51651,1096,47.47,68.17,0.522120933275828,{"v":2.19568791292002e-08,"d":"2.20E-08"},"*",{"v":2.9044E-9,"d":"2.90E-09"},"PTRH2","GO:0016020//membrane;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005739//mitochondrion","GO:0004045//aminoacyl-tRNA hydrolase activity","GO:2000811//negative regulation of anoikis;GO:2000210//positive regulation of anoikis;GO:0010629//negative regulation of gene expression;GO:0006915//apoptotic process","K04794//peptidyl-tRNA hydrolase, PTH2 family [EC:3.1.1.29]","XP_008968798.1//PREDICTED: peptidyl-tRNA hydrolase 2, mitochondrial isoform X1 [Pan paniscus];NP_001015509.1//peptidyl-tRNA hydrolase 2, mitochondrial isoform a [Homo sapiens]","4;2//1"]
[84557,994,8.47,12.15,0.520522439160945,0.0102506369025271,"*",0.00355506,"MAP1LC3A","GO:0044754//autolysosome;GO:0005874//microtubule;GO:0005770//late endosome;GO:0031090//organelle membrane;GO:0005829//cytosol;GO:0005776//autophagosome;GO:0000421//autophagosome membrane","GO:0008429//phosphatidylethanolamine binding;GO:0031625//ubiquitin protein ligase binding;GO:0005543//phospholipid binding","GO:0034198//cellular response to amino acid starvation;GO:0009267//cellular response to starvation;GO:0043278//response to morphine;GO:0071280//cellular response to copper ion;GO:0000422//autophagy of mitochondrion;GO:0097352//autophagosome maturation;GO:0010288//response to lead ion;GO:0006995//cellular response to nitrogen starvation;GO:0006914//autophagy;GO:0010040//response to iron(II) ion;GO:0000045//autophagosome assembly;GO:0016236//macroautophagy;GO:0070301//cellular response to hydrogen peroxide","K10435//microtubule-associated protein 1 light chain","XP_011527385.1//PREDICTED: microtubule-associated proteins 1A/1B light chain 3A isoform X1 [Homo sapiens];NP_852610.1//microtubule-associated proteins 1A/1B light chain 3A isoform b [Homo sapiens]","3//A2MP1;2//1"]
[4832,1038,15.84,22.72,0.520390499425072,0.000286809565794066,"*",{"v":7.20166e-05,"d":"7.20E-05"},"NME3","GO:0070062//extracellular exosome;GO:0005739//mitochondrion","GO:0005524//ATP binding;GO:0004550//nucleoside diphosphate kinase activity","GO:0006228//UTP biosynthetic process;GO:0006241//CTP biosynthetic process;GO:0006183//GTP biosynthetic process","K00940//nucleoside-diphosphate kinase [EC:2.7.4.6]","XP_017713829.1//PREDICTED: nucleoside diphosphate kinase 3 isoform X1 [Rhinopithecus bieti]","2//1"]
[3489,980,53.25,76.37,0.520224498380649,{"v":1.80086545893459e-11,"d":"1.80E-11"},"*",{"v":1.671894e-12,"d":"1.67E-12"},"IGFBP6","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0042568//insulin-like growth factor binary complex;GO:0005794//Golgi apparatus;GO:0005576//extracellular region","GO:0005520//insulin-like growth factor binding;GO:0031994//insulin-like growth factor I binding;GO:0005102//receptor binding;GO:0031995//insulin-like growth factor II binding","GO:0001558//regulation of cell growth;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0044267//cellular protein metabolic process;GO:0007165//signal transduction;GO:0043567//regulation of insulin-like growth factor receptor signaling pathway;GO:0008285//negative regulation of cell proliferation","K10138//insulin-like growth factor-binding protein 3;K00637//sterol O-acyltransferase [EC:2.3.1.26]","NP_002169.1//insulin-like growth factor-binding protein 6 precursor [Homo sapiens]","2//1"]
[59,1805,3.71,5.32,0.520007058880386,0.0327229366113373,"*",0.0130818,"ACTA2","NA","NA","NA","K12313//actin, aortic smooth muscle","XP_004858412.2//actin, aortic smooth muscle [Heterocephalus glaber];XP_019844282.1//PREDICTED: actin, aortic smooth muscle [Bos indicus];KFO23287.1//Actin, aortic smooth muscle [Fukomys damarensis]","1//3;3//A2MP1;2//1"]
[3660,2302,8.9,12.76,0.519751087911109,{"v":3.50572750731422e-05,"d":"3.51E-05"},"*",{"v":7.5013e-06,"d":"7.50E-06"},"IRF2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005925//focal adhesion;GO:0005829//cytosol","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0060337//type I interferon signaling pathway;GO:0008283//cell proliferation;GO:0007596//blood coagulation;GO:0006355//regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0051607//defense response to virus;GO:0006351//transcription, DNA-templated","K10153//interferon regulatory factor 2","XP_007998574.1//PREDICTED: interferon regulatory factor 2 isoform X1 [Chlorocebus sabaeus]","3//A2MP1"]
[653145,2049,8.03,11.51,0.519415940614916,0.00370909279442231,"*",0.001165622,"ANXA8","NA","GO:0005544//calcium-dependent phospholipid binding;GO:0005509//calcium ion binding","NA","K17096//annexin A8","NP_001258632.1//annexin A8 isoform 3 [Homo sapiens];BAG60903.1//unnamed protein product [Homo sapiens];NP_001258631.1//annexin A8 isoform 1 [Homo sapiens]","1//3;2//1"]
[51333,1460,5.22,7.48,0.518988463317752,0.0174484397422855,"*",6.4424E-3,"ZNF771","NA","GO:0003676//nucleic acid binding","NA","K09228//KRAB domain-containing zinc finger protein","XP_006148225.1//PREDICTED: zinc finger protein 771 [Tupaia chinensis];ELW66355.1//Zinc finger protein 629 [Tupaia chinensis]","1//3;3//A2MP1"]
[9020,4499,28.35,40.61,0.518486292094734,{"v":1.05658505636743E-27,"d":"1.06E-27"},"*",{"v":3.1683e-29,"d":"3.17E-29"},"MAP3K14","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005829//cytosol;GO:0001650//fibrillar center;GO:0005737//cytoplasm","GO:0004709//MAP kinase kinase kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004704//NF-kappaB-inducing kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0016301//kinase activity","GO:0023014//signal transduction by protein phosphorylation;GO:0038061//NIK/NF-kappaB signaling;GO:0007346//regulation of mitotic cell cycle;GO:0071260//cellular response to mechanical stimulus;GO:0051607//defense response to virus;GO:0032147//activation of protein kinase activity;GO:0031295//T cell costimulation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0006955//immune response;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0031098//stress-activated protein kinase signaling cascade;GO:0042981//regulation of apoptotic process","K04466//mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]","NP_003945.2//mitogen-activated protein kinase kinase kinase 14 [Homo sapiens]",4]
[4359,1970,0.37,0.53,0.518467088934249,0.557656471445929,"*",0.402236,"MPZ","GO:0016323//basolateral plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005791//rough endoplasmic reticulum;GO:0043209//myelin sheath;GO:0005764//lysosome;GO:0005886//plasma membrane","GO:0005198//structural molecule activity","GO:0042552//myelination;GO:0098742//cell-cell adhesion via plasma-membrane adhesion molecules;GO:0007268//chemical synaptic transmission;GO:0098743//cell aggregation;GO:0043066//negative regulation of apoptotic process","K06770//myelin protein zero","NP_001302420.1//myelin protein P0 isoform L-MPZ precursor [Homo sapiens]","1//3;7"]
[387509,4098,0.81,1.16,0.518130992242947,0.146654080178616,"*",0.0740156,"GPR153","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004930//G-protein coupled receptor activity","NA","K08437//G protein-coupled receptor 153","NP_997253.2//probable G-protein coupled receptor 153 [Homo sapiens]","3//A2MP1"]
[666,2663,14.44,20.67,0.517467646538277,{"v":7.42610298642534e-09,"d":"7.43E-09"},"*",{"v":9.2466e-10,"d":"9.25E-10"},"BOK","GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0005741//mitochondrial outer membrane;GO:0033106//cis-Golgi network membrane;GO:0005737//cytoplasm;GO:0032588//trans-Golgi network membrane;GO:0055038//recycling endosome membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005640//nuclear outer membrane;GO:0005634//nucleus;GO:0031901//early endosome membrane;GO:0005794//Golgi apparatus;GO:0005743//mitochondrial inner membrane;GO:0005789//endoplasmic reticulum membrane;GO:0031966//mitochondrial membrane","GO:0031625//ubiquitin protein ligase binding;GO:0046982//protein heterodimerization activity;GO:0051400//BH domain binding;GO:0005102//receptor binding;GO:0042803//protein homodimerization activity","GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:1901382//regulation of chorionic trophoblast cell proliferation;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:1904708//regulation of granulosa cell apoptotic process;GO:1903899//positive regulation of PERK-mediated unfolded protein response;GO:0051402//neuron apoptotic process;GO:0007420//brain development;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0008584//male gonad development;GO:0043065//positive regulation of apoptotic process;GO:0008283//cell proliferation;GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0010506//regulation of autophagy;GO:1900119//positive regulation of execution phase of apoptosis;GO:0001836//release of cytochrome c from mitochondria;GO:0051259//protein oligomerization;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:1902237//positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway;GO:0043524//negative regulation of neuron apoptotic process;GO:0048709//oligodendrocyte differentiation;GO:0060546//negative regulation of necroptotic process;GO:1901029//negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway;GO:0006915//apoptotic process;GO:1901030//positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway;GO:0051902//negative regulation of mitochondrial depolarization;GO:0008635//activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0042981//regulation of apoptotic process","K02561//Bcl-2-related ovarian killer protein","NP_115904.1//bcl-2-related ovarian killer protein [Homo sapiens]",4]
[79798,3997,5.69,8.14,0.516600141959666,{"v":2.26641390215589e-07,"d":"2.27E-07"},"*",{"v":3.42218e-08,"d":"3.42E-08"},"ARMC5","GO:0005654//nucleoplasm;GO:0005925//focal adhesion;GO:0005829//cytosol;GO:0005737//cytoplasm","NA","NA","K06237//collagen, type IV, alpha;K16628//collagen, type VII, alpha;K13172//serine/arginine repetitive matrix protein 2","NP_001288749.1//armadillo repeat-containing protein 5 isoform d [Homo sapiens];NP_001275696.1//armadillo repeat-containing protein 5 isoform c [Homo sapiens];EAW52133.1//armadillo repeat containing 5, isoform CRA_c, partial [Homo sapiens]","1//3;2//1"]
[6748,741,128.22,183.42,0.516529644227159,{"v":6.95524491456077e-19,"d":"6.96E-19"},"*",{"v":3.61826e-20,"d":"3.62E-20"},"SSR4","GO:0070062//extracellular exosome;GO:0005784//Sec61 translocon complex;GO:0016021//integral component of membrane","NA","NA","K04571//translocon-associated protein subunit delta","NP_001191456.1//translocon-associated protein subunit delta isoform 3 precursor [Homo sapiens];NP_001191455.1//translocon-associated protein subunit delta isoform 1 precursor [Homo sapiens]","1//3;2//1"]
[84954,1653,4.16,5.95,0.516306140054214,0.0337411861985019,"*",0.01353534,"MPND","NA","GO:0046872//metal ion binding;GO:0008237//metallopeptidase activity","NA","K19475//WAS/WASL-interacting protein","NP_001153318.1//MPN domain-containing protein isoform 2 [Homo sapiens];NP_116257.2//MPN domain-containing protein isoform 1 [Homo sapiens];XP_007993024.1//PREDICTED: MPN domain-containing protein [Chlorocebus sabaeus]","1//3;2//1;5"]
[571,5761,1.21,1.73,0.51576499036213,0.02353659351316,"*",0.00901298,"BACH1","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0031463//Cul3-RING ubiquitin ligase complex","GO:0020037//heme binding;GO:0001205//transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0001206//transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0006281//DNA repair;GO:0006355//regulation of transcription, DNA-templated;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0016567//protein ubiquitination;GO:0000117//regulation of transcription involved in G2/M transition of mitotic cell cycle;GO:0006366//transcription from RNA polymerase II promoter","K09042//transcription regulator BACH","NP_001177.1//transcription regulator protein BACH1 [Homo sapiens]","3//A2MP1;2//1"]
[977,1520,221.27,316.33,0.515622521766505,{"v":4.12053133333333e-69,"d":"4.12E-69"},"*",{"v":3.7919e-71,"d":"3.79E-71"},"CD151","GO:0016020//membrane;GO:0005887//integral component of plasma membrane;GO:0005925//focal adhesion;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005604//basement membrane","GO:0005178//integrin binding","GO:0016477//cell migration;GO:0007155//cell adhesion;GO:0042098//T cell proliferation;GO:0007166//cell surface receptor signaling pathway;GO:0031581//hemidesmosome assembly","K06537//CD151 antigen","NP_004348.2//CD151 antigen [Homo sapiens];XP_007993783.1//PREDICTED: CD151 antigen isoform X1 [Chlorocebus sabaeus]","4;1//3;3//A2MP1"]
[9050,3054,2.26,3.23,0.515211392278737,0.0260250266042003,"*",0.01008482,"PSTPIP2","GO:0016020//membrane;GO:0005856//cytoskeleton;GO:0005829//cytosol","GO:0003779//actin binding","GO:0016477//cell migration;GO:0007010//cytoskeleton organization","K20124//proline-serine-threonine phosphatase interacting protein 2","NP_077748.3//proline-serine-threonine phosphatase-interacting protein 2 [Homo sapiens]","3//A2MP1"]
[118932,3993,0.35,0.5,0.514573172829758,0.421977295844453,"*",0.277162,"ANKRD22","GO:0016021//integral component of membrane","NA","NA","K19406//lipase-like abhydrolase domain-containing protein 3 [EC:3.1.1.-]","NP_653191.2//ankyrin repeat domain-containing protein 22 [Homo sapiens]","2//1"]
[23263,6424,0.07,0.1,0.514573172829758,0.71867546658729,"*",0.60458,"MCF2L","GO:0012505//endomembrane system;GO:0005615//extracellular space;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0035091//phosphatidylinositol binding","GO:0043065//positive regulation of apoptotic process;GO:0035025//positive regulation of Rho protein signal transduction;GO:0035023//regulation of Rho protein signal transduction;GO:0035556//intracellular signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction","K20685//guanine nucleotide exchange factor MCF2","NP_001106203.2//guanine nucleotide exchange factor DBS isoform a [Homo sapiens];NP_079255.4//guanine nucleotide exchange factor DBS isoform b precursor [Homo sapiens];NP_001307744.1//guanine nucleotide exchange factor DBS isoform c precursor [Homo sapiens];NP_001307745.1//guanine nucleotide exchange factor DBS isoform d [Homo sapiens];NP_001307746.1//guanine nucleotide exchange factor DBS isoform e precursor [Homo sapiens]","4;1//3;2//1"]
[100505767,1242,0.14,0.2,0.514573172829758,0.781418860241136,"*",0.685686,"SPDYE18","NA","NA","NA","K08694//speedy","NP_001338277.1//speedy/RINGO cell cycle regulator family member E18 [Homo sapiens]","1//3"]
[376132,2620,0.07,0.1,0.514573172829758,0.78136311627907,"*",0.685686,"LRRC10","GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0030017//sarcomere","GO:0003779//actin binding;GO:0051393//alpha-actinin binding","GO:0055013//cardiac muscle cell development","K17277//epidermal growth factor receptor kinase substrate 8;K12796//erbb2-interacting protein","NP_963844.2//leucine-rich repeat-containing protein 10 [Homo sapiens]","3//A2MP1"]
[440503,2445,0.35,0.5,0.514573172829758,0.475893794344473,"*",0.324492,"PLIN5","GO:0005811//lipid droplet;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005737//cytoplasm","GO:0035473//lipase binding;GO:0042802//identical protein binding","GO:0060193//positive regulation of lipase activity;GO:0060192//negative regulation of lipase activity;GO:0031999//negative regulation of fatty acid beta-oxidation;GO:0010867//positive regulation of triglyceride biosynthetic process;GO:0032000//positive regulation of fatty acid beta-oxidation;GO:0010890//positive regulation of sequestering of triglyceride;GO:0051646//mitochondrion localization;GO:0010897//negative regulation of triglyceride catabolic process;GO:0035359//negative regulation of peroxisome proliferator activated receptor signaling pathway;GO:0034389//lipid particle organization;GO:0010884//positive regulation of lipid storage;GO:0019915//lipid storage;GO:2000378//negative regulation of reactive oxygen species metabolic process","K20255//perilipin-5","NP_001013728.2//perilipin-5 [Homo sapiens]","2//1"]
[40,2747,0.21,0.3,0.514573172829758,0.557559689691079,"*",0.402236,"ASIC2","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0043197//dendritic spine;GO:0005886//plasma membrane;GO:0043025//neuronal cell body","GO:0022839//ion gated channel activity;GO:0044736//acid-sensing ion channel activity;GO:0015280//ligand-gated sodium channel activity","GO:0010468//regulation of gene expression;GO:0019229//regulation of vasoconstriction;GO:0035418//protein localization to synapse;GO:0034220//ion transmembrane transport;GO:0051965//positive regulation of synapse assembly;GO:0030193//regulation of blood coagulation;GO:0007602//phototransduction;GO:0003026//regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback;GO:0042391//regulation of membrane potential;GO:0034765//regulation of ion transmembrane transport;GO:0043066//negative regulation of apoptotic process;GO:0007417//central nervous system development;GO:0010447//response to acidic pH;GO:0007605//sensory perception of sound;GO:0007268//chemical synaptic transmission;GO:0007422//peripheral nervous system development;GO:0015672//monovalent inorganic cation transport;GO:0050974//detection of mechanical stimulus involved in sensory perception;GO:0050915//sensory perception of sour taste","K04828//acid-sensing ion channel 2","NP_899233.1//acid-sensing ion channel 2 isoform MDEG2 [Homo sapiens];NP_001085.2//acid-sensing ion channel 2 isoform MDEG1 [Homo sapiens]","1//3;4"]
[7576,4608,0.07,0.1,0.514573172829758,0.830497708474576,"*",0.751524,"ZNF28","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_016789787.1//PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 28 [Pan troglodytes]","3//A2MP1"]
[84163,947,5.91,8.44,0.514084868529653,0.0671676789975794,"*",0.0295304,"GTF2IRD2","GO:0005654//nucleoplasm;GO:0005737//cytoplasm","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0003677//DNA binding","GO:0007275//multicellular organism development;GO:0006351//transcription, DNA-templated","K03121//transcription initiation factor TFII-I","NP_001268376.1//general transcription factor II-I repeat domain-containing protein 2A isoform 2 [Homo sapiens];NP_775808.3//general transcription factor II-I repeat domain-containing protein 2A isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[56033,1498,4.54,6.48,0.51330151559371,0.0287597740819907,"*",0.01128678,"BARX1","GO:0005634//nucleus","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0009952//anterior/posterior pattern specification;GO:0048513//animal organ development;GO:0006355//regulation of transcription, DNA-templated;GO:0009888//tissue development;GO:0030178//negative regulation of Wnt signaling pathway;GO:0007267//cell-cell signaling;GO:0055123//digestive system development;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0048536//spleen development;GO:0030855//epithelial cell differentiation","K09361//BarH-like homeobox","XP_011769558.1//PREDICTED: homeobox protein BarH-like 1 [Macaca nemestrina]","3//A2MP1"]
[7089,2708,1.1,1.57,0.513261035366967,0.21288195951417,"*",0.11521,"TLE2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005615//extracellular space;GO:0005925//focal adhesion;GO:0016604//nuclear body","GO:0003714//transcription corepressor activity","GO:0045892//negative regulation of transcription, DNA-templated;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:1904837//beta-catenin-TCF complex assembly;GO:0009887//animal organ morphogenesis;GO:0007165//signal transduction;GO:0006355//regulation of transcription, DNA-templated;GO:0016055//Wnt signaling pathway;GO:0006351//transcription, DNA-templated","K04497//groucho","NP_003251.2//transducin-like enhancer protein 2 isoform 1 [Homo sapiens];NP_001287775.1//transducin-like enhancer protein 2 isoform 4 [Homo sapiens];NP_001138233.1//transducin-like enhancer protein 2 isoform 2 [Homo sapiens];XP_010365609.1//PREDICTED: transducin-like enhancer protein 2 [Rhinopithecus roxellana]","4;1//3"]
[163033,2173,30.53,43.54,0.512113817981427,{"v":2.80640669949066e-14,"d":"2.81E-14"},"*",{"v":2.06958E-15,"d":"2.07E-15"},"ZNF579","GO:0005634//nucleus","GO:0003723//RNA binding;GO:0046872//metal ion binding;GO:0003677//DNA binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","NP_689813.2//zinc finger protein 579 [Homo sapiens]","2//1"]
[51131,1726,5.12,7.3,0.51175265376738,0.0105766781082539,"*",0.00368204,"PHF11","GO:0005654//nucleoplasm;GO:0031965//nuclear membrane","GO:0046872//metal ion binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K18494//histone-lysine N-methyltransferase SETDB2 [EC:2.1.1.43]","NP_001035533.1//PHD finger protein 11 isoform a [Homo sapiens]","2//1"]
[150383,1502,9.49,13.53,0.511681846955428,0.000929168724324324,"*",0.000258264,"CDPF1","NA","NA","NA","K22073//transferase CAF17, mitochondrial [EC:2.1.-.-]","XP_016794888.1//PREDICTED: cysteine-rich DPF motif domain-containing protein 1 isoform X4 [Pan troglodytes]",4]
[1428,1559,0.47,0.67,0.511500338780135,0.557753286805555,"*",0.402236,"CRYM","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005782//peroxisomal matrix;GO:0005739//mitochondrion;GO:0005737//cytoplasm","GO:0050661//NADP binding;GO:0047127//thiomorpholine-carboxylate dehydrogenase activity;GO:0003714//transcription corepressor activity;GO:0070324//thyroid hormone binding;GO:0042803//protein homodimerization activity;GO:0016639//oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0070327//thyroid hormone transport;GO:0007605//sensory perception of sound;GO:0006554//lysine catabolic process;GO:0042403//thyroid hormone metabolic process","K18258//thiomorpholine-carboxylate dehydrogenase [EC:1.5.1.25]","NP_001879.1//ketimine reductase mu-crystallin [Homo sapiens]",4]
[200844,2366,1.81,2.58,0.511381368340049,0.901883867952323,"*",0.843166,"C3orf67","NA","NA","NA","NA","XP_011531762.1//PREDICTED: uncharacterized protein C3orf67 isoform X8 [Homo sapiens];NP_001338462.1//uncharacterized protein C3orf67 isoform 5 [Homo sapiens];XP_011531761.1//PREDICTED: uncharacterized protein C3orf67 isoform X7 [Homo sapiens];NP_001338459.1//uncharacterized protein C3orf67 isoform 1 [Homo sapiens];NP_001338463.1//uncharacterized protein C3orf67 isoform 6 [Homo sapiens]","1//3;3//A2MP1"]
[3556,3972,1.2,1.71,0.510961919277379,0.165888439126214,"*",0.0855716,"IL1RAP","GO:0016020//membrane;GO:0005615//extracellular space;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:1990782//protein tyrosine kinase binding;GO:0004871//signal transducer activity;GO:0002114//interleukin-33 receptor activity;GO:0004908//interleukin-1 receptor activity","GO:1900006//positive regulation of dendrite development;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051965//positive regulation of synapse assembly;GO:0006954//inflammatory response;GO:0042094//interleukin-2 biosynthetic process;GO:0072602//interleukin-4 secretion;GO:0032754//positive regulation of interleukin-5 production;GO:0006955//immune response;GO:0032736//positive regulation of interleukin-13 production;GO:0006461//protein complex assembly;GO:0045087//innate immune response;GO:2000778//positive regulation of interleukin-6 secretion","K04723//interleukin 1 receptor accessory protein","NP_001161403.1//interleukin-1 receptor accessory protein isoform 3 precursor [Homo sapiens];NP_002173.1//interleukin-1 receptor accessory protein isoform 1 precursor [Homo sapiens];NP_608273.1//interleukin-1 receptor accessory protein isoform 2 precursor [Homo sapiens]","1//3;3//A2MP1"]
[8477,4522,0.33,0.47,0.510194732319184,0.370721795704346,"*",0.230152,"GPR65","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004930//G-protein coupled receptor activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway;GO:0090630//activation of GTPase activity;GO:0031532//actin cytoskeleton reorganization;GO:0006915//apoptotic process;GO:0051496//positive regulation of stress fiber assembly;GO:0035025//positive regulation of Rho protein signal transduction;GO:0010447//response to acidic pH;GO:0007275//multicellular organism development;GO:0006955//immune response;GO:0030819//positive regulation of cAMP biosynthetic process","K08416//G protein-coupled receptor 65","XP_011804845.1//PREDICTED: psychosine receptor [Colobus angolensis palliatus]","3//A2MP1"]
[23580,3121,40.74,57.99,0.509358157966504,{"v":1.76599147529412e-26,"d":"1.77E-26"},"*",{"v":5.63826e-28,"d":"5.64E-28"},"CDC42EP4","GO:0012505//endomembrane system;GO:0005913//cell-cell adherens junction;GO:0015630//microtubule cytoskeleton;GO:0015629//actin cytoskeleton;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0017049//GTP-Rho binding;GO:0005096//GTPase activator activity","GO:0007266//Rho protein signal transduction;GO:0031274//positive regulation of pseudopodium assembly;GO:0030838//positive regulation of actin filament polymerization;GO:0008360//regulation of cell shape","K14404//cleavage and polyadenylation specificity factor subunit 4","NP_036253.2//cdc42 effector protein 4 [Homo sapiens]",4]
[56938,7327,4.11,5.85,0.509298230789084,{"v":3.8823096872494e-07,"d":"3.88E-07"},"*",{"v":6.0614e-08,"d":"6.06E-08"},"ARNTL2","GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005667//transcription factor complex;GO:0005737//cytoplasm","GO:0000982//transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0070888//E-box binding;GO:0003700//DNA binding transcription factor activity;GO:0046983//protein dimerization activity","GO:0007623//circadian rhythm;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006355//regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0042753//positive regulation of circadian rhythm;GO:0009649//entrainment of circadian clock;GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated","K09099//aryl hydrocarbon receptor nuclear translocator-like protein 2","XP_003906194.2//aryl hydrocarbon receptor nuclear translocator-like protein 2 isoform X2 [Papio anubis];XP_016779241.1//PREDICTED: aryl hydrocarbon receptor nuclear translocator-like protein 2 isoform X13 [Pan troglodytes];XP_003906190.2//aryl hydrocarbon receptor nuclear translocator-like protein 2 isoform X3 [Papio anubis]","4;1//3"]
[84062,1372,7.87,11.2,0.50906319143748,0.0169414233333333,"*",0.00622338,"DTNBP1","GO:0010008//endosome membrane;GO:0030054//cell junction;GO:0005737//cytoplasm;GO:0030496//midbody;GO:0030426//growth cone;GO:0030672//synaptic vesicle membrane;GO:0016528//sarcoplasm;GO:0005829//cytosol;GO:0043197//dendritic spine;GO:0045211//postsynaptic membrane;GO:0030424//axon;GO:1904115//axon cytoplasm;GO:0031083//BLOC-1 complex;GO:0005634//nucleus;GO:0015630//microtubule cytoskeleton;GO:0033162//melanosome membrane;GO:0014069//postsynaptic density;GO:0043005//neuron projection;GO:0042383//sarcolemma;GO:0005789//endoplasmic reticulum membrane","NA","GO:0007596//blood coagulation;GO:0014059//regulation of dopamine secretion;GO:0001956//positive regulation of neurotransmitter secretion;GO:0048812//neuron projection morphogenesis;GO:0048490//anterograde synaptic vesicle transport;GO:0043506//regulation of JUN kinase activity;GO:0032091//negative regulation of protein binding;GO:0031175//neuron projection development;GO:0031532//actin cytoskeleton reorganization;GO:0060159//regulation of dopamine receptor signaling pathway;GO:0071901//negative regulation of protein serine/threonine kinase activity;GO:0060155//platelet dense granule organization;GO:0010628//positive regulation of gene expression;GO:0048813//dendrite morphogenesis;GO:0008089//anterograde axonal transport;GO:0032438//melanosome organization","K20189//dysbindin","NP_001258598.1//dysbindin isoform e [Homo sapiens];NP_001258597.1//dysbindin isoform d [Homo sapiens];NP_115498.2//dysbindin isoform a [Homo sapiens];NP_898861.1//dysbindin isoform b [Homo sapiens]","4;1//3;2//1"]
[8379,1809,4.09,5.82,0.508918309966535,0.0195385160655738,"*",0.00731196,"MAD1L1","GO:0072686//mitotic spindle;GO:0005643//nuclear pore;GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005813//centrosome;GO:0097431//mitotic spindle pole;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0005819//spindle;GO:0000777//condensed chromosome kinetochore;GO:0000776//kinetochore","GO:0042802//identical protein binding;GO:0043515//kinetochore binding","GO:0090235//regulation of metaphase plate congression;GO:0007093//mitotic cell cycle checkpoint;GO:0042130//negative regulation of T cell proliferation;GO:0051315//attachment of mitotic spindle microtubules to kinetochore;GO:0007062//sister chromatid cohesion;GO:0051301//cell division;GO:0048538//thymus development;GO:0007094//mitotic spindle assembly checkpoint","K06638//mitotic spindle assembly checkpoint protein MAD1","NP_003541.2//mitotic spindle assembly checkpoint protein MAD1 isoform a [Homo sapiens];XP_017749939.1//PREDICTED: mitotic spindle assembly checkpoint protein MAD1 isoform X4 [Rhinopithecus bieti];NP_001291453.1//mitotic spindle assembly checkpoint protein MAD1 isoform b precursor [Homo sapiens]","1//3;2//1"]
[7376,1962,50.65,72.07,0.508836576319529,{"v":7.46322901199041e-19,"d":"7.46E-19"},"*",{"v":3.89654e-20,"d":"3.90E-20"},"NR1H2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm","GO:0003707//steroid hormone receptor activity;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0051117//ATPase binding;GO:0004879//nuclear receptor activity;GO:0034191//apolipoprotein A-I receptor binding;GO:0046965//retinoid X receptor binding;GO:0001133//RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding;GO:0043565//sequence-specific DNA binding;GO:0008270//zinc ion binding;GO:0003700//DNA binding transcription factor activity","GO:0010875//positive regulation of cholesterol efflux;GO:0010867//positive regulation of triglyceride biosynthetic process;GO:0045861//negative regulation of proteolysis;GO:0032270//positive regulation of cellular protein metabolic process;GO:0032369//negative regulation of lipid transport;GO:0010884//positive regulation of lipid storage;GO:0048550//negative regulation of pinocytosis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0044255//cellular lipid metabolic process;GO:0042632//cholesterol homeostasis;GO:0090108//positive regulation of high-density lipoprotein particle assembly;GO:0090187//positive regulation of pancreatic juice secretion;GO:0045892//negative regulation of transcription, DNA-templated;GO:0090340//positive regulation of secretion of lysosomal enzymes;GO:0048384//retinoic acid receptor signaling pathway;GO:0060336//negative regulation of interferon-gamma-mediated signaling pathway;GO:0006351//transcription, DNA-templated;GO:0032376//positive regulation of cholesterol transport;GO:0010887//negative regulation of cholesterol storage;GO:0010745//negative regulation of macrophage derived foam cell differentiation;GO:0045723//positive regulation of fatty acid biosynthetic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0051006//positive regulation of lipoprotein lipase activity;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:2000188//regulation of cholesterol homeostasis","K08535//liver X receptor beta","XP_012365439.1//PREDICTED: oxysterols receptor LXR-beta isoform X1 [Nomascus leucogenys];NP_001243576.1//oxysterols receptor LXR-beta isoform 2 [Homo sapiens]","1//3;5"]
[7389,1408,18.79,26.73,0.508494770823023,{"v":4.14236106091718e-06,"d":"4.14E-06"},"*",{"v":7.5773e-07,"d":"7.58E-07"},"UROD","GO:0005654//nucleoplasm;GO:0005829//cytosol","GO:0004853//uroporphyrinogen decarboxylase activity","GO:0006782//protoporphyrinogen IX biosynthetic process;GO:0006783//heme biosynthetic process","K01599//uroporphyrinogen decarboxylase [EC:4.1.1.37]","NP_000365.3//uroporphyrinogen decarboxylase [Homo sapiens]",4]
[150290,2581,2.25,3.2,0.508146903670325,0.172833366883586,"*",0.0897816,"DUSP18","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005743//mitochondrial inner membrane;GO:0005737//cytoplasm","GO:0017017//MAP kinase tyrosine/serine/threonine phosphatase activity;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0016791//phosphatase activity","GO:0035970//peptidyl-threonine dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0016311//dephosphorylation","K14165//atypical dual specificity phosphatase [EC:3.1.3.16 3.1.3.48]","NP_001291725.1//dual specificity protein phosphatase 18 isoform b [Homo sapiens];NP_689724.3//dual specificity protein phosphatase 18 isoform a [Homo sapiens]","1//3;4"]
[79957,2124,5.69,8.09,0.507711050123396,0.00667553309159585,"*",0.00221278,"PAQR6","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0003707//steroid hormone receptor activity;GO:0005496//steroid binding","GO:0048545//response to steroid hormone","K17387//kinesin family member 23;K21125//mucin-5AC;K07297//adiponectin receptor","XP_008972790.1//PREDICTED: progestin and adipoQ receptor family member 6 isoform X12 [Pan paniscus];XP_004002657.2//PREDICTED: progestin and adipoQ receptor family member 6 isoform X1 [Ovis aries];XP_008972795.1//PREDICTED: progestin and adipoQ receptor family member 6 isoform X17 [Pan paniscus];NP_001259038.1//progestin and adipoQ receptor family member 6 isoform 7 [Homo sapiens];XP_017365484.1//PREDICTED: progestin and adipoQ receptor family member 6 isoform X3 [Cebus capucinus imitator];XP_017707931.1//PREDICTED: progestin and adipoQ receptor family member 6 isoform X1 [Rhinopithecus bieti];XP_008972791.1//PREDICTED: progestin and adipoQ receptor family member 6 isoform X13 [Pan paniscus];NP_001259035.1//progestin and adipoQ receptor family member 6 isoform 4 [Homo sapiens];XP_008972777.1//PREDICTED: progestin and adipoQ receptor family member 6 isoform X3 [Pan paniscus]","1//3;3//A2MP1;2//1"]
[4615,2660,18.66,26.53,0.507675689376937,{"v":3.30011706320142e-10,"d":"3.30E-10"},"*",{"v":3.49762e-11,"d":"3.50E-11"},"MYD88","GO:0010008//endosome membrane;GO:0005634//nucleus;GO:0043234//protein complex;GO:0005829//cytosol;GO:0014069//postsynaptic density;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0035325//Toll-like receptor binding;GO:0005121//Toll binding;GO:0070976//TIR domain binding;GO:0042802//identical protein binding;GO:0005123//death receptor binding;GO:0043621//protein self-association;GO:0005149//interleukin-1 receptor binding","GO:0046330//positive regulation of JNK cascade;GO:0060337//type I interferon signaling pathway;GO:0032481//positive regulation of type I interferon production;GO:0016064//immunoglobulin mediated immune response;GO:0071260//cellular response to mechanical stimulus;GO:0032740//positive regulation of interleukin-17 production;GO:0007166//cell surface receptor signaling pathway;GO:0032760//positive regulation of tumor necrosis factor production;GO:0070555//response to interleukin-1;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0002238//response to molecule of fungal origin;GO:0007165//signal transduction;GO:0050671//positive regulation of lymphocyte proliferation;GO:0043066//negative regulation of apoptotic process;GO:0010628//positive regulation of gene expression;GO:0006915//apoptotic process;GO:0009682//induced systemic resistance;GO:0044130//negative regulation of growth of symbiont in host;GO:0019221//cytokine-mediated signaling pathway;GO:1900017//positive regulation of cytokine production involved in inflammatory response;GO:0032494//response to peptidoglycan;GO:1902622//regulation of neutrophil migration;GO:0032755//positive regulation of interleukin-6 production;GO:0070935//3'-UTR-mediated mRNA stabilization;GO:0034162//toll-like receptor 9 signaling pathway;GO:0008063//Toll signaling pathway;GO:0050830//defense response to Gram-positive bacterium;GO:2000338//regulation of chemokine (C-X-C motif) ligand 1 production;GO:0032747//positive regulation of interleukin-23 production;GO:0090557//establishment of endothelial intestinal barrier;GO:0045351//type I interferon biosynthetic process;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0140052//cellular response to oxidised low-density lipoprotein particle stimulus;GO:0002224//toll-like receptor signaling pathway;GO:0006954//inflammatory response;GO:0007254//JNK cascade;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0050727//regulation of inflammatory response;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0045080//positive regulation of chemokine biosynthetic process;GO:2000341//regulation of chemokine (C-X-C motif) ligand 2 production;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0009615//response to virus","K04729//myeloid differentiation primary response protein MyD88","NP_002459.2//myeloid differentiation primary response protein MyD88 isoform 2 [Homo sapiens];ANK58157.1//myeloid differentiation primary response 88 [Homo sapiens];NP_001166039.1//myeloid differentiation primary response protein MyD88 isoform 3 [Homo sapiens];NP_001166038.1//myeloid differentiation primary response protein MyD88 isoform 1 [Homo sapiens];NP_001166040.1//myeloid differentiation primary response protein MyD88 isoform 4 [Homo sapiens]","4;1//3"]
[126119,877,52.36,74.44,0.507612958113911,{"v":2.08521610526316e-09,"d":"2.09E-09"},"*",{"v":2.43062E-10,"d":"2.43E-10"},"JOSD2","GO:0005829//cytosol","GO:0004843//thiol-dependent ubiquitin-specific protease activity;GO:0036459//thiol-dependent ubiquitinyl hydrolase activity","GO:0016579//protein deubiquitination","K15235//josephin [EC:3.4.19.12]","AAH51380.1//JOSD2 protein, partial [Homo sapiens];XP_008986709.1//PREDICTED: josephin-2 isoform X3 [Callithrix jacchus]","1//3;3//A2MP1"]
[91734,1359,2.15,3.05,0.504472582860788,0.20084188441528,"*",0.1072984,"IDI2","GO:0005829//cytosol;GO:0005777//peroxisome","GO:0046872//metal ion binding;GO:0016787//hydrolase activity;GO:0004452//isopentenyl-diphosphate delta-isomerase activity","GO:0008299//isoprenoid biosynthetic process;GO:0009240//isopentenyl diphosphate biosynthetic process;GO:0046490//isopentenyl diphosphate metabolic process;GO:0006695//cholesterol biosynthetic process;GO:0050992//dimethylallyl diphosphate biosynthetic process","K01823//isopentenyl-diphosphate Delta-isomerase [EC:5.3.3.2]","NP_150286.1//isopentenyl-diphosphate delta-isomerase 2 [Homo sapiens]","2//1"]
[662,1268,6.63,9.4,0.503651886452412,0.027273005984252,"*",0.01062476,"BNIP1","GO:0043231//intracellular membrane-bounded organelle;GO:0005783//endoplasmic reticulum;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0031201//SNARE complex;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005739//mitochondrion","GO:0005484//SNAP receptor activity","GO:0097194//execution phase of apoptosis;GO:0016320//endoplasmic reticulum membrane fusion;GO:0006914//autophagy;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0043066//negative regulation of apoptotic process;GO:0007029//endoplasmic reticulum organization;GO:0006915//apoptotic process","K08497//protein transport protein SEC20","NP_053581.2//vesicle transport protein SEC20 isoform BNIP1-a [Homo sapiens];XP_012620958.1//vesicle transport protein SEC20 isoform X1 [Microcebus murinus];NP_053582.2//vesicle transport protein SEC20 isoform BNIP1-b [Homo sapiens];NP_053583.2//vesicle transport protein SEC20 isoform BNIP1-c [Homo sapiens]","2//1"]
[966,7592,22.43,31.8,0.503597145085445,{"v":4.53057737802817E-35,"d":"4.53E-35"},"*",{"v":1.006858E-36,"d":"1.01E-36"},"CD59","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0043218//compact myelin;GO:0031362//anchored component of external side of plasma membrane;GO:0005925//focal adhesion;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0031982//vesicle;GO:0000139//Golgi membrane;GO:0009986//cell surface;GO:0030133//transport vesicle;GO:0035579//specific granule membrane;GO:0042383//sarcolemma;GO:0005789//endoplasmic reticulum membrane;GO:0070821//tertiary granule membrane;GO:0005886//plasma membrane;GO:0012507//ER to Golgi transport vesicle membrane","GO:0001848//complement binding","GO:0030449//regulation of complement activation;GO:0007596//blood coagulation;GO:0042102//positive regulation of T cell proliferation;GO:0048208//COPII vesicle coating;GO:0043066//negative regulation of apoptotic process;GO:0007166//cell surface receptor signaling pathway;GO:0001775//cell activation;GO:0001971//negative regulation of activation of membrane attack complex;GO:0043312//neutrophil degranulation;GO:0006888//ER to Golgi vesicle-mediated transport","K04008//CD59 antigen","XP_011820940.1//PREDICTED: CD59 glycoprotein isoform X2 [Mandrillus leucophaeus];NP_000602.1//CD59 glycoprotein preproprotein [Homo sapiens];XP_012359677.1//PREDICTED: CD59 glycoprotein isoform X1 [Nomascus leucogenys]","1//3;2//1;5"]
[205860,1641,26.82,38.02,0.503449294744078,{"v":2.63208108704883e-09,"d":"2.63E-09"},"*",{"v":3.10432E-10,"d":"3.10E-10"},"TRIML2","NA","GO:0016740//transferase activity","GO:0016567//protein ubiquitination;GO:0032526//response to retinoic acid","K12039//tripartite motif family-like protein 2","NP_001290348.1//probable E3 ubiquitin-protein ligase TRIML2 isoform 1 [Homo sapiens];NP_775824.2//probable E3 ubiquitin-protein ligase TRIML2 isoform 2 [Homo sapiens]","1//3;2//1"]
[26074,4120,0.12,0.17,0.502500340529183,0.811351076491622,"*",0.724446,"CFAP61","GO:0031514//motile cilium;GO:0005737//cytoplasm;GO:0005930//axoneme","NA","GO:0003341//cilium movement;GO:0044782//cilium organization","K06756//neuronal cell adhesion molecule;K12869//crooked neck","XP_010367420.1//PREDICTED: uncharacterized protein C20orf26 homolog isoform X2 [Rhinopithecus roxellana];NP_056400.3//cilia- and flagella-associated protein 61 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[51160,1092,40.96,58.01,0.502085903985904,{"v":8.88915577181208e-10,"d":"8.89E-10"},"*",{"v":9.9498e-11,"d":"9.95E-11"},"VPS28","GO:0043657//host cell;GO:0070062//extracellular exosome;GO:0010008//endosome membrane;GO:0031902//late endosome membrane;GO:0000813//ESCRT I complex;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005769//early endosome","GO:0043130//ubiquitin binding;GO:0032403//protein complex binding","GO:0031397//negative regulation of protein ubiquitination;GO:0016197//endosomal transport;GO:0043328//protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0019058//viral life cycle;GO:0039702//viral budding via host ESCRT complex;GO:0036258//multivesicular body assembly;GO:0045732//positive regulation of protein catabolic process;GO:0075733//intracellular transport of virus;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0016236//macroautophagy;GO:2000397//positive regulation of ubiquitin-dependent endocytosis","K12184//ESCRT-I complex subunit VPS28","XP_011831091.1//PREDICTED: vacuolar protein sorting-associated protein 28 homolog isoform X1 [Mandrillus leucophaeus];XP_012328725.1//vacuolar protein sorting-associated protein 28 homolog isoform X1 [Aotus nancymaae]","3//A2MP1;2//1"]
[23253,11321,1.97,2.79,0.502069492372812,{"v":3.07039828436299e-05,"d":"3.07E-05"},"*",{"v":6.50254e-06,"d":"6.50E-06"},"ANKRD12","GO:0005654//nucleoplasm;GO:0005829//cytosol","NA","NA","K21436//ankyrin repeat domain-containing protein 11/12","NP_056023.3//ankyrin repeat domain-containing protein 12 isoform 1 [Homo sapiens];NP_001077094.1//ankyrin repeat domain-containing protein 12 isoform 2 [Homo sapiens]","4;1//3;2//1"]
[342667,3202,2.79,3.95,0.501587531235278,0.0119426258414613,"*",4.21588E-3,"STAC2","GO:0005622//intracellular","GO:0046872//metal ion binding","GO:0035556//intracellular signal transduction","K01368//cathepsin S [EC:3.4.22.27];K17985//activating molecule in BECN1-regulated autophagy protein 1;K01064//wingless-type MMTV integration site family, member 9","XP_019494012.1//PREDICTED: SH3 and cysteine-rich domain-containing protein 2 isoform X1 [Hipposideros armiger];NP_945344.1//SH3 and cysteine-rich domain-containing protein 2 isoform 1 [Homo sapiens]","4;1//3"]
[23677,5193,19.58,27.72,0.501546492533519,{"v":8.5397838954608e-21,"d":"8.54E-21"},"*",{"v":3.88658e-22,"d":"3.89E-22"},"SH3BP4","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0030136//clathrin-coated vesicle;GO:0005905//clathrin-coated pit;GO:0005737//cytoplasm","GO:0042802//identical protein binding;GO:0017016//Ras GTPase binding;GO:0005092//GDP-dissociation inhibitor activity","GO:0032007//negative regulation of TOR signaling;GO:0030308//negative regulation of cell growth;GO:0061462//protein localization to lysosome;GO:0050790//regulation of catalytic activity;GO:0010508//positive regulation of autophagy;GO:0071230//cellular response to amino acid stimulus;GO:0006897//endocytosis;GO:0034260//negative regulation of GTPase activity;GO:0008285//negative regulation of cell proliferation","K20066//SH3 domain-binding protein 4","NP_055336.1//SH3 domain-binding protein 4 [Homo sapiens]","2//1"]
[116211,1032,6.19,8.76,0.500991460386909,0.027934749955157,"*",0.01091928,"TM4SF19","GO:0016021//integral component of membrane","NA","NA","K00681//gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13];K13624//ceruloplasmin [EC:1.16.3.1]","NP_001191827.1//transmembrane 4 L6 family member 19 isoform 3 [Homo sapiens];NP_612470.2//transmembrane 4 L6 family member 19 isoform 1 [Homo sapiens];NP_001191826.1//transmembrane 4 L6 family member 19 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[1051,2113,121.71,172.24,0.500972516239805,{"v":9.29220649636364e-51,"d":"9.29E-51"},"*",{"v":1.279758e-52,"d":"1.28E-52"},"CEBPB","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0036488//CHOP-C/EBP complex;GO:0000779//condensed chromosome, centromeric region;GO:0016363//nuclear matrix;GO:0000790//nuclear chromatin;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0035259//glucocorticoid receptor binding;GO:0003705//transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0019900//kinase binding;GO:0003700//DNA binding transcription factor activity;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0042826//histone deacetylase binding;GO:0042803//protein homodimerization activity;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0035035//histone acetyltransferase binding;GO:0008134//transcription factor binding","GO:0097421//liver regeneration;GO:0034976//response to endoplasmic reticulum stress;GO:0071222//cellular response to lipopolysaccharide;GO:0001892//embryonic placenta development;GO:0042130//negative regulation of T cell proliferation;GO:0071347//cellular response to interleukin-1;GO:0032753//positive regulation of interleukin-4 production;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045600//positive regulation of fat cell differentiation;GO:0043524//negative regulation of neuron apoptotic process;GO:0033598//mammary gland epithelial cell proliferation;GO:0001541//ovarian follicle development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0060644//mammary gland epithelial cell differentiation;GO:0002432//granuloma formation;GO:0050873//brown fat cell differentiation;GO:0060850//regulation of transcription involved in cell fate commitment;GO:0035711//T-helper 1 cell activation;GO:0006355//regulation of transcription, DNA-templated;GO:0032496//response to lipopolysaccharide;GO:0042742//defense response to bacterium;GO:0071407//cellular response to organic cyclic compound;GO:0045408//regulation of interleukin-6 biosynthetic process;GO:0030182//neuron differentiation;GO:0006953//acute-phase response;GO:0072574//hepatocyte proliferation;GO:0045669//positive regulation of osteoblast differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0006954//inflammatory response;GO:0071230//cellular response to amino acid stimulus;GO:1990440//positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress;GO:0007613//memory;GO:0045670//regulation of osteoclast differentiation;GO:0006955//immune response","K10048//CCAAT/enhancer binding protein (C/EBP), beta","NP_005185.2//CCAAT/enhancer-binding protein beta isoform a [Homo sapiens]","1//3;3//A2MP1"]
[55017,2960,22.51,31.85,0.500727315689507,{"v":7.86939583319706e-14,"d":"7.87E-14"},"*",{"v":6.02496E-15,"d":"6.02E-15"},"C14orf119","GO:0005829//cytosol;GO:0005739//mitochondrion","NA","NA","K04372//MAP kinase interacting serine/threonine kinase [EC:2.7.11.1];K12581//CCR4-NOT transcription complex subunit 7/8;K16506//protocadherin Fat 1/2/3","NP_060394.1//uncharacterized protein C14orf119 [Homo sapiens]","3//A2MP1"]
[1503,2716,48.06,68,0.500698097895198,{"v":3.7293239559633e-20,"d":"3.73E-20"},"*",{"v":1.781316e-21,"d":"1.78E-21"},"CTPS1","GO:0016020//membrane","GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0003883//CTP synthase activity","GO:0006541//glutamine metabolic process;GO:0042098//T cell proliferation;GO:0042100//B cell proliferation;GO:0044210//'de novo' CTP biosynthetic process","K01937//CTP synthase [EC:6.3.4.2]","XP_003432053.1//CTP synthase 1 [Canis lupus familiaris]","1//3;3//A2MP1"]
[440348,1389,3.23,4.57,0.500660000364145,0.0972546574576727,"*",0.0453092,"NPIPB15","GO:0005654//nucleoplasm;GO:0005576//extracellular region","NA","NA","NA","NP_001293023.1//nuclear pore complex-interacting protein family member B15 precursor [Homo sapiens]","1//3"]
[7791,2323,128.09,181.22,0.500584335740311,{"v":1.33735364151351E-58,"d":"1.34E-58"},"*",{"v":1.548832E-60,"d":"1.55E-60"},"ZYX","NA","NA","NA","K06273//zyxin","XP_016868076.1//PREDICTED: zyxin isoform X1 [Homo sapiens];EAW51849.1//zyxin, isoform CRA_b [Homo sapiens]","1//3;4"]
[4709,770,33.78,47.79,0.50053943944508,{"v":1.08535081719051E-5,"d":"1.09E-05"},"*",{"v":2.11852e-06,"d":"2.12E-06"},"NDUFB3","GO:0070062//extracellular exosome;GO:0005747//mitochondrial respiratory chain complex I;GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane","GO:0008137//NADH dehydrogenase (ubiquinone) activity","GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0022900//electron transport chain;GO:0006120//mitochondrial electron transport, NADH to ubiquinone","K03959//NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 3","NP_002482.1//NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 [Homo sapiens]","1//3;2//1"]
[192286,906,127.76,180.74,0.500479609953562,{"v":1.99817642446483E-22,"d":"2.00E-22"},"*",{"v":8.18084e-24,"d":"8.18E-24"},"HIGD2A","GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0070469//respiratory chain","NA","GO:0097250//mitochondrial respiratory chain supercomplex assembly;GO:0043066//negative regulation of apoptotic process;GO:0055114//oxidation-reduction process","NA","XP_003280545.1//PREDICTED: HIG1 domain family member 2A, mitochondrial [Nomascus leucogenys]","3//A2MP1"]
[112399,2722,3.19,4.51,0.499571009490512,0.0145650155486111,"*",0.00525194,"EGLN3","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;GO:0005506//iron ion binding;GO:0031545//peptidyl-proline 4-dioxygenase activity;GO:0031418//L-ascorbic acid binding;GO:0031543//peptidyl-proline dioxygenase activity","GO:0042127//regulation of cell proliferation;GO:0018401//peptidyl-proline hydroxylation to 4-hydroxy-L-proline;GO:0001666//response to hypoxia;GO:0006915//apoptotic process;GO:0043523//regulation of neuron apoptotic process;GO:1990830//cellular response to leukemia inhibitory factor;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0018126//protein hydroxylation","K09592//hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]","XP_021035020.1//egl nine homolog 3 isoform X1 [Mus caroli];NP_001295032.1//egl nine homolog 3 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[389610,4980,0.87,1.23,0.499571009490512,0.091206820113852,"*",0.0421262,"XKR5","GO:0016021//integral component of membrane","NA","NA","K11447//histone demethylase [EC:1.14.11.-];K15144//mediator of RNA polymerase II transcription subunit 1;K17599//transmembrane protein 132","NP_997294.3//XK-related protein 5 isoform a [Homo sapiens];Q6UX68.1//RecName: Full=XK-related protein 5","1//3;4"]
[90480,772,43.98,62.17,0.499370974682477,{"v":4.0977910512e-07,"d":"4.10E-07"},"*",{"v":6.41322e-08,"d":"6.41E-08"},"GADD45GIP1","GO:0005759//mitochondrial matrix;GO:0005634//nucleus;GO:0005761//mitochondrial ribosome;GO:0005739//mitochondrion","NA","GO:0071850//mitotic cell cycle arrest;GO:1903862//positive regulation of oxidative phosphorylation;GO:0070126//mitochondrial translational termination;GO:0016032//viral process;GO:0008284//positive regulation of cell proliferation;GO:0070125//mitochondrial translational elongation","K22020//mucin-19","NP_443082.2//growth arrest and DNA damage-inducible proteins-interacting protein 1 [Homo sapiens]","3//A2MP1"]
[9168,482,2612.2,3692.38,0.499285675730629,{"v":1.38856657333333e-225,"d":"1.39E-225"},"*",{"v":2.08624e-228,"d":"2.09E-228"},"TMSB10","NA","NA","NA","K13785//thymosin beta 10","EAW99547.1//thymosin, beta 10, isoform CRA_a, partial [Homo sapiens]","3//A2MP1"]
[115701,7303,3.75,5.3,0.499101764067318,{"v":3.02452252941176E-6,"d":"3.02E-06"},"*",{"v":5.40756e-07,"d":"5.41E-07"},"ALPK2","GO:0005737//cytoplasm","GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding","NA","K08868//alpha-kinase","NP_443179.3//alpha-protein kinase 2 [Homo sapiens]","3//A2MP1"]
[11068,1414,11.45,16.18,0.498864009445671,0.000787709888,"*",0.00021574,"CYB561D2","NA","NA","NA","K08371//cytochrome b-561 domain containing protein 2","XP_014306202.1//PREDICTED: cytochrome b561 domain-containing protein 2 isoform X2 [Myotis lucifugus]","1//3;4"]
[257169,2091,0.46,0.65,0.498805856971442,0.514024695605381,"*",0.358794,"C9orf43","NA","NA","NA","K07524//regulator of G-protein signalling 3","NP_001265559.1//uncharacterized protein C9orf43 isoform 2 [Homo sapiens]","1//3;2//1"]
[222865,2841,1.09,1.54,0.498602215917975,0.147010700185943,"*",0.0742416,"TMEM130","GO:0005887//integral component of plasma membrane;GO:0005794//Golgi apparatus;GO:0000139//Golgi membrane","NA","NA","K04613//vomeronasal 2 receptor;K01064//wingless-type MMTV integration site family, member 9","XP_017389197.1//PREDICTED: transmembrane protein 130 isoform X2 [Cebus capucinus imitator];NP_001127923.1//transmembrane protein 130 isoform c precursor [Homo sapiens];XP_017389196.1//PREDICTED: transmembrane protein 130 isoform X1 [Cebus capucinus imitator]","1//3;2//1"]
[200172,2163,0.63,0.89,0.498453507466481,0.421856673463554,"*",0.277162,"SLFNL1","NA","GO:0005524//ATP binding","NA","K16628//collagen, type VII, alpha;K22020//mucin-19","NP_659427.3//schlafen-like protein 1 isoform 1 [Homo sapiens];NP_001287788.1//schlafen-like protein 1 isoform 2 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[54985,745,255.72,361.24,0.498392651911242,{"v":5.61587752727273e-36,"d":"5.62E-36"},"*",{"v":1.198832e-37,"d":"1.20E-37"},"HCFC1R1","GO:0005654//nucleoplasm;GO:0005737//cytoplasm","NA","NA","K09187//histone-lysine N-methyltransferase MLL2 [EC:2.1.1.43];K19475//WAS/WASL-interacting protein","NP_001275596.1//host cell factor C1 regulator 1 isoform 3 [Homo sapiens];XP_014688662.1//PREDICTED: host cell factor C1 regulator 1 isoform X1 [Equus asinus];XP_012297321.1//host cell factor C1 regulator 1 isoform X1 [Aotus nancymaae];NP_001002017.1//host cell factor C1 regulator 1 isoform 2 [Homo sapiens];NP_060355.1//host cell factor C1 regulator 1 isoform 1 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[7186,2298,15.95,22.53,0.498290889583196,{"v":7.11898550660793e-08,"d":"7.12E-08"},"*",{"v":1.01165E-8,"d":"1.01E-08"},"TRAF2","GO:0012506//vesicle membrane;GO:0045121//membrane raft;GO:0005938//cell cortex;GO:0005829//cytosol;GO:0009898//cytoplasmic side of plasma membrane;GO:1990604//IRE1-TRAF2-ASK1 complex;GO:0035631//CD40 receptor complex;GO:1990597//AIP1-IRE1 complex","GO:0042802//identical protein binding;GO:0005174//CD40 receptor binding;GO:0008270//zinc ion binding;GO:0031435//mitogen-activated protein kinase kinase kinase binding;GO:0019899//enzyme binding;GO:0004842//ubiquitin-protein transferase activity;GO:0032403//protein complex binding","GO:0097300//programmed necrotic cell death;GO:0051865//protein autoubiquitination;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0071732//cellular response to nitric oxide;GO:0051291//protein heterooligomerization;GO:1903721//positive regulation of I-kappaB phosphorylation;GO:0097296//activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:1903265//positive regulation of tumor necrosis factor-mediated signaling pathway;GO:0007250//activation of NF-kappaB-inducing kinase activity;GO:0034351//negative regulation of glial cell apoptotic process;GO:0030163//protein catabolic process;GO:0051023//regulation of immunoglobulin secretion;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0046328//regulation of JNK cascade;GO:0043623//cellular protein complex assembly","K03173//TNF receptor-associated factor 2 [EC:2.3.2.27]","XP_011517275.1//PREDICTED: TNF receptor-associated factor 2 isoform X1 [Homo sapiens]","3//A2MP1"]
[9274,1107,36.72,51.85,0.49777793028678,{"v":1.54271534070159E-8,"d":"1.54E-08"},"*",{"v":2.00976e-09,"d":"2.01E-09"},"BCL7C","NA","NA","GO:0006915//apoptotic process","K19719//collagen, type II, alpha;K06237//collagen, type IV, alpha;K13171//serine/arginine repetitive matrix protein 1;K19720//collagen, type III, alpha;K16882//protein piccolo","NP_001273455.1//B-cell CLL/lymphoma 7 protein family member C isoform 1 [Homo sapiens];NP_004756.2//B-cell CLL/lymphoma 7 protein family member C isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[23546,1029,1.36,1.92,0.497499659470817,0.42193708072048,"*",0.277162,"SYNGR4","GO:0030672//synaptic vesicle membrane;GO:0031594//neuromuscular junction;GO:0016021//integral component of membrane","NA","NA","K03006//DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6];K04403//TAK1-binding protein 1;K17783//mitochondrial FAD-linked sulfhydryl oxidase [EC:1.8.3.2];K21988//transmembrane channel-like protein","NP_036583.2//synaptogyrin-4 [Homo sapiens]","3//A2MP1"]
[146853,1034,0.56,0.79,0.496425826119499,0.634263715638236,"*",0.4781,"C17orf50","NA","NA","NA","K13172//serine/arginine repetitive matrix protein 2;K17498//transcription factor SPN1","XP_012640941.1//uncharacterized protein C17orf50 homolog isoform X4 [Microcebus murinus]","3//A2MP1"]
[8170,4167,0.95,1.34,0.496233582126825,0.112148641239821,"*",0.0534556,"SLC14A2","GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0050839//cell adhesion molecule binding;GO:0015204//urea transmembrane transporter activity","GO:0055085//transmembrane transport;GO:0015840//urea transport","K08716//solute carrier family 14 (urea transporter)","NP_009094.3//urea transporter 2 [Homo sapiens]","1//3;3//A2MP1"]
[95,1549,16.08,22.68,0.4961532337633,{"v":2.57890078657074E-5,"d":"2.58E-05"},"*",{"v":5.38576e-06,"d":"5.39E-06"},"ACY1","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0008237//metallopeptidase activity;GO:0042802//identical protein binding;GO:0004046//aminoacylase activity","GO:0006520//cellular amino acid metabolic process;GO:0006805//xenobiotic metabolic process","K14677//aminoacylase [EC:3.5.1.14]","NP_001185827.1//aminoacylase-1 isoform d [Homo sapiens];NP_001303260.1//ABHD14A-ACY1 readthrough (NMD candidate) [Homo sapiens];NP_001185826.1//aminoacylase-1 isoform c [Homo sapiens];NP_001185825.1//aminoacylase-1 isoform b [Homo sapiens]","1//3;2//1"]
[56915,1006,61.79,87.14,0.495961739812166,{"v":2.793846833213E-12,"d":"2.79E-12"},"*",{"v":2.42236E-13,"d":"2.42E-13"},"EXOSC5","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000176//nuclear exosome (RNase complex);GO:0035327//transcriptionally active chromatin;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0000177//cytoplasmic exosome (RNase complex);GO:0005829//cytosol;GO:0000178//exosome (RNase complex)","GO:0003723//RNA binding;GO:0000175//3'-5'-exoribonuclease activity","GO:0043928//exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay;GO:0031125//rRNA 3'-end processing;GO:0016075//rRNA catabolic process;GO:0034427//nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5';GO:0051607//defense response to virus;GO:0071028//nuclear mRNA surveillance;GO:0006364//rRNA processing;GO:0071051//polyadenylation-dependent snoRNA 3'-end processing;GO:0043488//regulation of mRNA stability;GO:0034475//U4 snRNA 3'-end processing;GO:0045006//DNA deamination","K12590//exosome complex component RRP46","AAM75154.1//chronic myelogenous leukemia tumor antigen 28 [Homo sapiens]","3//A2MP1"]
[79155,1807,13.95,19.67,0.49573183556198,{"v":9.76367779896486E-5,"d":"9.76E-05"},"*",{"v":2.2438e-05,"d":"2.24E-05"},"TNIP2","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0070530//K63-linked polyubiquitin modification-dependent protein binding;GO:0046872//metal ion binding;GO:0031593//polyubiquitin modification-dependent protein binding;GO:0019901//protein kinase binding","GO:0071222//cellular response to lipopolysaccharide;GO:0070498//interleukin-1-mediated signaling pathway;GO:0034134//toll-like receptor 2 signaling pathway;GO:0034162//toll-like receptor 9 signaling pathway;GO:0016579//protein deubiquitination;GO:0023035//CD40 signaling pathway;GO:0034138//toll-like receptor 3 signaling pathway;GO:0043032//positive regulation of macrophage activation;GO:0006351//transcription, DNA-templated;GO:0050871//positive regulation of B cell activation;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:0006915//apoptotic process;GO:0006954//inflammatory response;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0050821//protein stabilization;GO:0051403//stress-activated MAPK cascade","K10402//kinesin family member 20;K10352//myosin heavy chain;K16731//golgin subfamily A member 1;K07210//inhibitor of nuclear factor kappa-B kinase subunit gamma;K02990//small subunit ribosomal protein S6;K16456//centrosomal protein CEP55","XP_011914611.1//PREDICTED: TNFAIP3-interacting protein 2 isoform X2 [Cercocebus atys];NP_077285.3//TNFAIP3-interacting protein 2 isoform 1 [Homo sapiens];NP_001278945.1//TNFAIP3-interacting protein 2 isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[83886,1360,1.05,1.48,0.495207847962827,0.358069297683437,"*",0.219652,"PRSS27","GO:0005886//plasma membrane","GO:0004252//serine-type endopeptidase activity","NA","K09628//serine protease 27 [EC:3.4.21.-]","XP_004057067.1//PREDICTED: serine protease 27 isoform X1 [Gorilla gorilla gorilla]","4;1//3"]
[10475,5629,2.1,2.96,0.495207847962827,3.79288460540971E-3,"*",0.001193854,"TRIM38","GO:0005829//cytosol;GO:0005622//intracellular","GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0004871//signal transducer activity","GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0016567//protein ubiquitination;GO:0046598//positive regulation of viral entry into host cell","K12014//tripartite motif-containing protein 38 [EC:2.3.2.27]","NP_006346.1//E3 ubiquitin-protein ligase TRIM38 [Homo sapiens]",4]
[22921,1811,6.31,8.89,0.494543413847221,5.79491902184745E-3,"*",0.001892944,"MSRB2","GO:0005829//cytosol;GO:0005739//mitochondrion","GO:0003779//actin binding;GO:0033743//peptide-methionine (R)-S-oxide reductase activity;GO:0033745//L-methionine-(R)-S-oxide reductase activity;GO:0008270//zinc ion binding;GO:0003700//DNA binding transcription factor activity","GO:0006979//response to oxidative stress;GO:0030091//protein repair;GO:0030041//actin filament polymerization","K07305//peptide-methionine (R)-S-oxide reductase [EC:1.8.4.12]","XP_001155268.3//PREDICTED: methionine-R-sulfoxide reductase B2, mitochondrial [Pan troglodytes]","3//A2MP1"]
[51087,1606,0.86,1.21,0.492598482572497,0.421896873260911,"*",0.277162,"YBX2","GO:0005634//nucleus;GO:0001650//fibrillar center;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0003677//DNA binding","GO:0048599//oocyte development;GO:0006355//regulation of transcription, DNA-templated;GO:0009386//translational attenuation;GO:0007283//spermatogenesis;GO:0006366//transcription from RNA polymerase II promoter","K09277//Y-box-binding protein 2","NP_057066.2//Y-box-binding protein 2 [Homo sapiens]","3//A2MP1"]
[54958,696,27.96,39.33,0.492265825567474,0.000240985561378611,"*",{"v":5.95298E-5,"d":"5.95E-05"},"TMEM160","GO:0016021//integral component of membrane;GO:0005739//mitochondrion","NA","NA","K19720//collagen, type III, alpha","XP_003316511.2//PREDICTED: transmembrane protein 160 [Pan troglodytes]","1//3"]
[126328,824,113.3,159.35,0.492051157957338,{"v":9.40878360081466e-17,"d":"9.41E-17"},"*",{"v":5.78404e-18,"d":"5.78E-18"},"NDUFA11","GO:0005747//mitochondrial respiratory chain complex I;GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion","NA","GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0055114//oxidation-reduction process","K03956//NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 11","NP_783313.1//NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 isoform 1 [Homo sapiens];BAC87088.1//unnamed protein product [Homo sapiens]","4;1//3"]
[59340,3422,0.32,0.45,0.491853096329675,0.542758258420086,"*",0.388398,"HRH4","GO:0005623//cell;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004969//histamine receptor activity","GO:0007194//negative regulation of adenylate cyclase activity;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0043408//regulation of MAPK cascade;GO:0006954//inflammatory response","K04152//histamine receptor H4","NP_001137300.1//histamine H4 receptor isoform 2 [Homo sapiens];NP_067637.2//histamine H4 receptor isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[50855,1270,1.28,1.8,0.491853096329675,0.392537189465409,"*",0.25006,"PARD6A","NA","NA","NA","K06093//partitioning defective protein 6","EAW83152.1//hCG2025821, isoform CRA_b [Homo sapiens]","1//3;2//1"]
[54461,2390,42.89,60.31,0.491755919224471,{"v":6.6602956503856e-20,"d":"6.66E-20"},"*",{"v":3.24384E-21,"d":"3.24E-21"},"FBXW5","GO:0080008//Cul4-RING E3 ubiquitin ligase complex;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0019005//SCF ubiquitin ligase complex","GO:0004842//ubiquitin-protein transferase activity;GO:0019901//protein kinase binding","GO:0043687//post-translational protein modification;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0010824//regulation of centrosome duplication;GO:0007088//regulation of mitotic nuclear division;GO:0000209//protein polyubiquitination","K10263//F-box and WD-40 domain protein 5","XP_008003741.1//PREDICTED: F-box/WD repeat-containing protein 5 [Chlorocebus sabaeus]","3//A2MP1"]
[613037,3904,31.15,43.79,0.491369286541287,{"v":1.44018965311475e-23,"d":"1.44E-23"},"*",{"v":5.49966E-25,"d":"5.50E-25"},"NPIPB13","GO:0005654//nucleoplasm;GO:0016021//integral component of membrane","NA","NA","K09187//histone-lysine N-methyltransferase MLL2 [EC:2.1.1.43]","NP_001308821.1//nuclear pore complex-interacting protein family member B13 [Homo sapiens]","1//3"]
[79144,832,326.96,459.59,0.491233258939792,{"v":1.60021087553648E-49,"d":"1.60E-49"},"*",{"v":2.3341e-51,"d":"2.33E-51"},"PPDPF","NA","NA","GO:0001708//cell fate specification;GO:0031017//exocrine pancreas development","K13909//mucin-7;K05853//Ca2+ transporting ATPase, sarcoplasmic/endoplasmic reticulum [EC:3.6.3.8];K02599//Notch 1","XP_011789835.1//PREDICTED: pancreatic progenitor cell differentiation and proliferation factor [Colobus angolensis palliatus];XP_017355202.1//PREDICTED: uncharacterized protein LOC108283384 [Cebus capucinus imitator]","1//3;3//A2MP1"]
[4487,1940,4.39,6.17,0.49104954961406,0.0182113299173554,"*",0.00675942,"MSX1","GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0000982//transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0002039//p53 binding;GO:0043565//sequence-specific DNA binding;GO:0035326//enhancer binding;GO:0001227//transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding","GO:0071316//cellular response to nicotine;GO:0090427//activation of meiosis;GO:0030513//positive regulation of BMP signaling pathway;GO:0035880//embryonic nail plate morphogenesis;GO:0061312//BMP signaling pathway involved in heart development;GO:0042474//middle ear morphogenesis;GO:0021983//pituitary gland development;GO:0051154//negative regulation of striated muscle cell differentiation;GO:0043517//positive regulation of DNA damage response, signal transduction by p53 class mediator;GO:0008285//negative regulation of cell proliferation;GO:0061180//mammary gland epithelium development;GO:0060349//bone morphogenesis;GO:0035116//embryonic hindlimb morphogenesis;GO:0043066//negative regulation of apoptotic process;GO:0042475//odontogenesis of dentin-containing tooth;GO:0030900//forebrain development;GO:0007275//multicellular organism development;GO:0009952//anterior/posterior pattern specification;GO:2000678//negative regulation of transcription regulatory region DNA binding;GO:0003198//epithelial to mesenchymal transition involved in endocardial cushion formation;GO:0030901//midbrain development;GO:0006355//regulation of transcription, DNA-templated;GO:0023019//signal transduction involved in regulation of gene expression;GO:0060536//cartilage morphogenesis;GO:0060021//palate development;GO:0042481//regulation of odontogenesis;GO:0010463//mesenchymal cell proliferation;GO:0000902//cell morphogenesis;GO:0030308//negative regulation of cell growth;GO:0006351//transcription, DNA-templated;GO:0001701//in utero embryonic development;GO:0007517//muscle organ development;GO:2001055//positive regulation of mesenchymal cell apoptotic process;GO:0035115//embryonic forelimb morphogenesis;GO:0048863//stem cell differentiation;GO:0060325//face morphogenesis;GO:1902255//positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator;GO:0034504//protein localization to nucleus;GO:0050821//protein stabilization","K09341//homeobox protein MSX","NP_002439.2//homeobox protein MSX-1 [Homo sapiens]","3//A2MP1"]
[84179,2108,0.37,0.52,0.490986352512142,0.578782204572804,"*",0.421532,"SLC49A3","GO:0016021//integral component of membrane","NA","GO:0055085//transmembrane transport","K12306//MFS transporter, FLVCR family, MFS-domain-containing protein 7","NP_115595.2//major facilitator superfamily domain-containing protein 7 isoform 2 [Homo sapiens];NP_001281270.1//major facilitator superfamily domain-containing protein 7 isoform 1 [Homo sapiens];NP_001281271.1//major facilitator superfamily domain-containing protein 7 isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[6193,755,703.32,987.67,0.489847846321682,{"v":3.533225164e-95,"d":"3.53E-95"},"*",{"v":2.21186E-97,"d":"2.21E-97"},"RPS5","NA","NA","NA","K02989//small subunit ribosomal protein S5e","XP_017706028.1//PREDICTED: 40S ribosomal protein S5 isoform X1 [Rhinopithecus bieti]","3//A2MP1"]
[363,2654,1.41,1.98,0.489805267680816,0.16997556450677,"*",0.0880204,"AQP6","NA","NA","NA","K09868//aquaporin-6","XP_008001382.1//PREDICTED: aquaporin-6 [Chlorocebus sabaeus]","3//A2MP1"]
[6999,1703,0.57,0.8,0.489038080722621,0.514116913885899,"*",0.358794,"TDO2","GO:0005829//cytosol","GO:0046872//metal ion binding;GO:0020037//heme binding;GO:0016597//amino acid binding;GO:0042802//identical protein binding;GO:0004833//tryptophan 2,3-dioxygenase activity;GO:0019825//oxygen binding","GO:0019442//tryptophan catabolic process to acetyl-CoA;GO:0051289//protein homotetramerization;GO:0006569//tryptophan catabolic process;GO:0019441//tryptophan catabolic process to kynurenine","K00453//tryptophan 2,3-dioxygenase [EC:1.13.11.11]","NP_005642.1//tryptophan 2,3-dioxygenase [Homo sapiens]","3//A2MP1"]
[100505549,2012,2.28,3.2,0.489038080722621,0.103336429801413,"*",0.0485372,"LOC100505549","NA","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K06245//laminin, beta 4;K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9]","NP_001229733.1//uncharacterized protein LOC100505549 [Homo sapiens]","1//3"]
[7920,2025,6.8,9.54,0.48845451986781,0.00205563942448464,"*",0.000611776,"ABHD16A","GO:0016021//integral component of membrane","GO:0047372//acylglycerol lipase activity","GO:0052651//monoacylglycerol catabolic process;GO:1905344//prostaglandin catabolic process","K08869//aarF domain-containing kinase","XP_004043725.2//PREDICTED: protein ABHD16A isoform X1 [Gorilla gorilla gorilla];NP_001170986.1//protein ABHD16A isoform b [Homo sapiens]","1//3;2//1"]
[22904,4948,23.23,32.56,0.48711154545744,{"v":5.17122160592593e-22,"d":"5.17E-22"},"*",{"v":2.18516E-23,"d":"2.19E-23"},"SBNO2","NA","NA","GO:0045892//negative regulation of transcription, DNA-templated;GO:0030282//bone mineralization;GO:0071222//cellular response to lipopolysaccharide;GO:0006351//transcription, DNA-templated;GO:0072675//osteoclast fusion;GO:0061430//bone trabecula morphogenesis;GO:0050727//regulation of inflammatory response;GO:1990830//cellular response to leukemia inhibitory factor;GO:0071354//cellular response to interleukin-6;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0002281//macrophage activation involved in immune response;GO:0071348//cellular response to interleukin-11","K16628//collagen, type VII, alpha","NP_055778.2//protein strawberry notch homolog 2 isoform 1 [Homo sapiens];NP_001093592.1//protein strawberry notch homolog 2 isoform 2 [Homo sapiens]","1//3;2//1"]
[1471,947,221.57,310.52,0.486923635204928,{"v":1.998539088e-35,"d":"2.00E-35"},"*",{"v":4.37892e-37,"d":"4.38E-37"},"CST3","GO:1904724//tertiary granule lumen;GO:0070062//extracellular exosome;GO:0005788//endoplasmic reticulum lumen;GO:0030424//axon;GO:0005783//endoplasmic reticulum;GO:0031965//nuclear membrane;GO:0005615//extracellular space;GO:0005764//lysosome;GO:0043292//contractile fiber;GO:0048471//perinuclear region of cytoplasm;GO:0043025//neuronal cell body;GO:0005771//multivesicular body;GO:0005576//extracellular region;GO:1904813//ficolin-1-rich granule lumen;GO:0005604//basement membrane","GO:0002020//protease binding;GO:0001540//amyloid-beta binding;GO:0042802//identical protein binding;GO:0004866//endopeptidase inhibitor activity;GO:0004869//cysteine-type endopeptidase inhibitor activity","GO:0043687//post-translational protein modification;GO:0060311//negative regulation of elastin catabolic process;GO:0007420//brain development;GO:0007566//embryo implantation;GO:0043067//regulation of programmed cell death;GO:0044267//cellular protein metabolic process;GO:0007431//salivary gland development;GO:0032355//response to estradiol;GO:0034103//regulation of tissue remodeling;GO:0010716//negative regulation of extracellular matrix disassembly;GO:0070301//cellular response to hydrogen peroxide;GO:0042493//response to drug;GO:0010466//negative regulation of peptidase activity;GO:0001654//eye development;GO:0060313//negative regulation of blood vessel remodeling;GO:0045740//positive regulation of DNA replication;GO:0001666//response to hypoxia;GO:0006915//apoptotic process;GO:2000117//negative regulation of cysteine-type endopeptidase activity;GO:0042747//circadian sleep/wake cycle, REM sleep;GO:0009743//response to carbohydrate;GO:0045861//negative regulation of proteolysis;GO:0010711//negative regulation of collagen catabolic process;GO:0009636//response to toxic substance;GO:0043312//neutrophil degranulation;GO:0048678//response to axon injury;GO:0060009//Sertoli cell development;GO:0001775//cell activation;GO:0006952//defense response;GO:0031667//response to nutrient levels;GO:0060548//negative regulation of cell death;GO:0097435//supramolecular fiber organization;GO:0008284//positive regulation of cell proliferation","K13899//cystatin-C","NP_000090.1//cystatin-C precursor [Homo sapiens]","1//3;3//A2MP1"]
[113675,1427,8.32,11.66,0.486912355059404,0.0048884352,"*",0.001574496,"SDSL","GO:0070062//extracellular exosome;GO:0005739//mitochondrion","GO:0003941//L-serine ammonia-lyase activity;GO:0042802//identical protein binding;GO:0030170//pyridoxal phosphate binding;GO:0004794//L-threonine ammonia-lyase activity","GO:0006520//cellular amino acid metabolic process","K17989//L-serine/L-threonine ammonia-lyase [EC:4.3.1.17 4.3.1.19]","XP_016874252.1//PREDICTED: serine dehydratase-like isoform X1 [Homo sapiens]","1//3;3//A2MP1"]
[10979,3351,14.9,20.88,0.48680938122036,{"v":4.86964520973349e-10,"d":"4.87E-10"},"*",{"v":5.26168e-11,"d":"5.26E-11"},"FERMT2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005925//focal adhesion;GO:0005938//cell cortex;GO:0005737//cytoplasm;GO:0031258//lamellipodium membrane;GO:0001725//stress fiber;GO:0009986//cell surface;GO:0005829//cytosol;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0031674//I band;GO:0031941//filamentous actin","GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding","GO:0034329//cell junction assembly;GO:0034446//substrate adhesion-dependent cell spreading;GO:0072657//protein localization to membrane;GO:0008360//regulation of cell shape;GO:0033622//integrin activation;GO:0007160//cell-matrix adhesion;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0016055//Wnt signaling pathway;GO:0007229//integrin-mediated signaling pathway;GO:0048041//focal adhesion assembly","K17083//kindlin 2","XP_006076361.1//PREDICTED: fermitin family homolog 2 isoform X3 [Bubalus bubalis];NP_001128472.1//fermitin family homolog 2 isoform 3 [Homo sapiens];CAA80852.1//mitogen inducible gene mig-2, partial [Homo sapiens]","1//3;2//1"]
[10669,1123,5.27,7.38,0.485817854423181,0.0382321173182305,"*",0.01563606,"CGREF1","GO:0005576//extracellular region","GO:0005509//calcium ion binding","GO:0007155//cell adhesion;GO:0006950//response to stress;GO:0007050//cell cycle arrest;GO:0008285//negative regulation of cell proliferation","K03006//DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6];K19538//retinitis pigmentosa 1;K00846//ketohexokinase [EC:2.7.1.3];K06831//galectin-3","NP_006560.3//cell growth regulator with EF hand domain protein 1 isoform a precursor [Homo sapiens];EAX00636.1//cell growth regulator with EF-hand domain 1, isoform CRA_b [Homo sapiens]","1//3;5"]
[170954,4035,18.29,25.61,0.485652177848752,{"v":1.29061285405405E-7,"d":"1.29E-07"},"*",{"v":1.883322e-08,"d":"1.88E-08"},"PPP1R18","GO:0005856//cytoskeleton;GO:0005737//cytoplasm","GO:0003779//actin binding;GO:0019902//phosphatase binding","NA","K17559//phostensin","NP_597728.1//phostensin [Homo sapiens]","1//3;3//A2MP1"]
[388021,3336,0.05,0.07,0.485426827170242,0.782535412159749,"*",0.685686,"TMEM179","GO:0016021//integral component of membrane","NA","NA","K03006//DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6];K09312//homeobox protein CDX1/4;K06840//semaphorin 3;K19607//X-linked retinitis pigmentosa GTPase regulator","EAW81868.1//FLJ42486 protein, isoform CRA_b [Homo sapiens];XP_012353428.1//PREDICTED: transmembrane protein 179 isoform X2 [Nomascus leucogenys]","1//3"]
[1757,3234,0.05,0.07,0.485426827170242,0.782255975146408,"*",0.685686,"SARDH","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0008480//sarcosine dehydrogenase activity;GO:0016491//oxidoreductase activity","GO:1901053//sarcosine catabolic process;GO:0042426//choline catabolic process","K00314//sarcosine dehydrogenase [EC:1.5.8.3]","NP_009032.2//sarcosine dehydrogenase, mitochondrial precursor [Homo sapiens]","1//3;3//A2MP1"]
[283229,1848,1.2,1.68,0.485426827170242,0.397779978696621,"*",0.25716,"CRACR2B","GO:0005737//cytoplasm","GO:0005509//calcium ion binding","GO:2001256//regulation of store-operated calcium entry;GO:0034613//cellular protein localization;GO:0002115//store-operated calcium entry","K17199//Ras and EF-hand domain-containing protein","EAX02397.1//hypothetical protein MGC45840, isoform CRA_a, partial [Homo sapiens];NP_775855.3//EF-hand calcium-binding domain-containing protein 4A isoform 2 [Homo sapiens]","1//3;4"]
[122953,3843,6.05,8.47,0.485426827170242,{"v":1.95665560331593E-5,"d":"1.96E-05"},"*",{"v":3.9895e-06,"d":"3.99E-06"},"JDP2","GO:0005634//nucleus","GO:0003677//DNA binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0046982//protein heterodimerization activity;GO:0003700//DNA binding transcription factor activity;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0031065//positive regulation of histone deacetylation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0031063//regulation of histone deacetylation;GO:0006351//transcription, DNA-templated;GO:0045599//negative regulation of fat cell differentiation","K09033//jun dimerization protein 2","XP_005343429.2//PREDICTED: LOW QUALITY PROTEIN: jun dimerization protein 2 [Microtus ochrogaster];XP_016876460.1//PREDICTED: jun dimerization protein 2 isoform X1 [Homo sapiens];NP_001128521.1//jun dimerization protein 2 isoform b [Homo sapiens];XP_011763810.1//PREDICTED: jun dimerization protein 2 isoform X1 [Macaca nemestrina]","1//3;3//A2MP1"]
[51393,2829,0.2,0.28,0.485426827170242,0.634474486998422,"*",0.4781,"TRPV2","GO:0044295//axonal growth cone;GO:0005622//intracellular;GO:0042470//melanosome;GO:0032584//growth cone membrane;GO:0044297//cell body;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005216//ion channel activity;GO:0015075//ion transmembrane transporter activity;GO:0005262//calcium channel activity;GO:0005261//cation channel activity","GO:0006810//transport;GO:0045773//positive regulation of axon extension;GO:0070588//calcium ion transmembrane transport;GO:0090280//positive regulation of calcium ion import;GO:0007600//sensory perception;GO:0009408//response to heat;GO:0009266//response to temperature stimulus","K04971//transient receptor potential cation channel subfamily V member 2","NP_057197.2//transient receptor potential cation channel subfamily V member 2 [Homo sapiens]",4]
[143630,2350,0.1,0.14,0.485426827170242,0.81066903005254,"*",0.724446,"UBQLNL","NA","NA","NA","K22254//ubiquilin-like protein","BAC87218.1//unnamed protein product [Homo sapiens]",4]
[6768,3319,0.05,0.07,0.485426827170242,0.780861778284737,"*",0.685686,"ST14","GO:0070062//extracellular exosome;GO:0016323//basolateral plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0019897//extrinsic component of plasma membrane","GO:0004252//serine-type endopeptidase activity;GO:0004175//endopeptidase activity;GO:0008236//serine-type peptidase activity","GO:0006508//proteolysis;GO:0030216//keratinocyte differentiation;GO:0001843//neural tube closure;GO:0060672//epithelial cell morphogenesis involved in placental branching;GO:0070268//cornification","K08670//suppressor of tumorigenicity protein 14 [EC:3.4.21.109]","NP_068813.1//suppressor of tumorigenicity 14 protein [Homo sapiens]","3//A2MP1"]
[168507,9092,0.05,0.07,0.485426827170242,0.718247874460806,"*",0.60458,"PKD1L1","GO:0016020//membrane;GO:0005929//cilium;GO:0060170//ciliary membrane;GO:0034704//calcium channel complex;GO:0097730//non-motile cilium","GO:0005262//calcium channel activity","GO:0098609//cell-cell adhesion;GO:0070986//left/right axis specification;GO:0050982//detection of mechanical stimulus;GO:0003127//detection of nodal flow","K04987//polycystin 1L1","XP_016867287.1//PREDICTED: polycystic kidney disease protein 1-like 1 isoform X1 [Homo sapiens]",4]
[55786,2673,0.65,0.91,0.485426827170242,0.344778488540161,"*",0.20906,"ZNF415","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_012613294.1//zinc finger protein 415 isoform X3 [Microcebus murinus];XP_012613292.1//zinc finger protein 415 isoform X2 [Microcebus murinus];XP_012613289.1//zinc finger protein 415 isoform X1 [Microcebus murinus]","1//3;3//A2MP1;2//1"]
[4015,4159,0.15,0.21,0.485426827170242,0.557704874924052,"*",0.402236,"LOX","GO:0005634//nucleus;GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005578//proteinaceous extracellular matrix","GO:0005507//copper ion binding;GO:0004720//protein-lysine 6-oxidase activity","GO:0030324//lung development;GO:0042493//response to drug;GO:0007507//heart development;GO:0042060//wound healing;GO:0030199//collagen fibril organization;GO:0048251//elastic fiber assembly;GO:0048545//response to steroid hormone;GO:0006464//cellular protein modification process;GO:0048514//blood vessel morphogenesis;GO:0030198//extracellular matrix organization;GO:0035904//aorta development","K00277//protein-lysine 6-oxidase [EC:1.4.3.13]","NP_002308.2//protein-lysine 6-oxidase isoform 1 preproprotein [Homo sapiens];XP_017715216.1//PREDICTED: protein-lysine 6-oxidase [Rhinopithecus bieti]","6;1//3;2//1"]
[2644,713,2.95,4.13,0.485426827170242,0.328953406948357,"*",0.1973844,"GCHFR","GO:0030425//dendrite;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0042470//melanosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043234//protein complex","GO:0016787//hydrolase activity;GO:0016597//amino acid binding;GO:0030742//GTP-dependent protein binding;GO:0004857//enzyme inhibitor activity;GO:0044549//GTP cyclohydrolase binding","GO:0051291//protein heterooligomerization;GO:0042133//neurotransmitter metabolic process;GO:0009890//negative regulation of biosynthetic process;GO:0043105//negative regulation of GTP cyclohydrolase I activity;GO:0050999//regulation of nitric-oxide synthase activity;GO:0006809//nitric oxide biosynthetic process","NA","XP_019500533.1//PREDICTED: GTP cyclohydrolase 1 feedback regulatory protein [Hipposideros armiger]","2//1"]
[254263,1356,2.1,2.94,0.485426827170242,0.227062239432177,"*",0.1261678,"CNIH2","GO:0016021//integral component of membrane;GO:0043197//dendritic spine;GO:0014069//postsynaptic density","NA","GO:0006810//transport;GO:2000311//regulation of AMPA receptor activity","K20368//protein cornichon","XP_012612935.2//protein cornichon homolog 2 [Microcebus murinus]","2//1"]
[7053,2679,0.15,0.21,0.485426827170242,0.695269131036558,"*",0.578622,"TGM3","GO:0070062//extracellular exosome;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0005737//cytoplasm","GO:0016746//transferase activity, transferring acyl groups;GO:0005509//calcium ion binding;GO:0003824//catalytic activity;GO:0003810//protein-glutamine gamma-glutamyltransferase activity","GO:0018149//peptide cross-linking;GO:0043163//cell envelope organization;GO:0031069//hair follicle morphogenesis;GO:0006464//cellular protein modification process;GO:0030216//keratinocyte differentiation;GO:0051262//protein tetramerization;GO:0031424//keratinization","K05620//transglutaminase 3 [EC:2.3.2.13]","NP_003236.3//protein-glutamine gamma-glutamyltransferase E [Homo sapiens]","3//A2MP1"]
[283,742,7.19,10.06,0.484566629366229,0.0762012853474742,"*",0.0341842,"ANG","GO:0070062//extracellular exosome;GO:0005605//basal lamina;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0031410//cytoplasmic vesicle;GO:0032311//angiogenin-PRI complex;GO:0043025//neuronal cell body;GO:0030426//growth cone;GO:0005730//nucleolus;GO:0005576//extracellular region","GO:0003677//DNA binding;GO:0005102//receptor binding;GO:0042277//peptide binding;GO:0042803//protein homodimerization activity;GO:0003676//nucleic acid binding;GO:0003779//actin binding;GO:0005507//copper ion binding;GO:0008201//heparin binding;GO:0004540//ribonuclease activity;GO:0004519//endonuclease activity;GO:0019843//rRNA binding","GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0032148//activation of protein kinase B activity;GO:0016477//cell migration;GO:0001890//placenta development;GO:0032431//activation of phospholipase A2 activity;GO:0017148//negative regulation of translation;GO:0001938//positive regulation of endothelial cell proliferation;GO:0050830//defense response to Gram-positive bacterium;GO:0001878//response to yeast;GO:0045087//innate immune response;GO:0030041//actin filament polymerization;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0042592//homeostatic process;GO:0030154//cell differentiation;GO:0001525//angiogenesis;GO:0007154//cell communication;GO:0006651//diacylglycerol biosynthetic process;GO:0001556//oocyte maturation;GO:0001541//ovarian follicle development;GO:0001666//response to hypoxia;GO:0050714//positive regulation of protein secretion;GO:0034332//adherens junction organization;GO:0042327//positive regulation of phosphorylation;GO:0019732//antifungal humoral response;GO:0007202//activation of phospholipase C activity;GO:0009725//response to hormone;GO:0009303//rRNA transcription;GO:0019731//antibacterial humoral response","K16631//angiogenin [EC:3.1.27.-]","NP_001136.1//angiogenin precursor [Homo sapiens];EAW66445.1//hCG2044783, isoform CRA_a [Homo sapiens]","4;2//1"]
[11135,2182,43.69,61.12,0.484341437591531,{"v":5.78005357765363e-18,"d":"5.78E-18"},"*",{"v":3.23848e-19,"d":"3.24E-19"},"CDC42EP1","GO:0012505//endomembrane system;GO:0005856//cytoskeleton;GO:0005925//focal adhesion;GO:0005913//cell-cell adherens junction;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0098641//cadherin binding involved in cell-cell adhesion;GO:0017049//GTP-Rho binding;GO:0005096//GTPase activator activity","GO:0007266//Rho protein signal transduction;GO:0031274//positive regulation of pseudopodium assembly;GO:0030838//positive regulation of actin filament polymerization;GO:0008360//regulation of cell shape","K12826//splicing factor 3A subunit 2","NP_689449.1//cdc42 effector protein 1 [Homo sapiens]","2//1"]
[342897,1973,1.63,2.28,0.484161859933664,0.191752823121387,"*",0.1017584,"NCCRP1","GO:0070062//extracellular exosome;GO:0005737//cytoplasm","NA","GO:0008284//positive regulation of cell proliferation","K02927//large subunit ribosomal protein L40e;K10102//F-box protein 27;K15696//RING finger protein 113B;K17985//activating molecule in BECN1-regulated autophagy protein 1;K01064//wingless-type MMTV integration site family, member 9","NP_001001414.1//F-box only protein 50 [Homo sapiens]","1//3"]
[51548,1462,21.49,30.05,0.483699508170765,{"v":2.05918493361884e-05,"d":"2.06E-05"},"*",{"v":4.21402e-06,"d":"4.21E-06"},"SIRT6","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005724//nuclear telomeric heterochromatin;GO:0005737//cytoplasm","GO:0003714//transcription corepressor activity;GO:0017136//NAD-dependent histone deacetylase activity;GO:0003950//NAD+ ADP-ribosyltransferase activity;GO:0070403//NAD+ binding;GO:0003682//chromatin binding;GO:0046969//NAD-dependent histone deacetylase activity (H3-K9 specific);GO:0008270//zinc ion binding;GO:0034979//NAD-dependent protein deacetylase activity;GO:0003956//NAD(P)+-protein-arginine ADP-ribosyltransferase activity","GO:0006284//base-excision repair;GO:1905564//positive regulation of vascular endothelial cell proliferation;GO:0031940//positive regulation of chromatin silencing at telomere;GO:1902732//positive regulation of chondrocyte proliferation;GO:0010569//regulation of double-strand break repair via homologous recombination;GO:0042593//glucose homeostasis;GO:2000648//positive regulation of stem cell proliferation;GO:0003247//post-embryonic cardiac muscle cell growth involved in heart morphogenesis;GO:0031648//protein destabilization;GO:0006471//protein ADP-ribosylation;GO:0008285//negative regulation of cell proliferation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0046325//negative regulation of glucose import;GO:1905555//positive regulation blood vessel branching;GO:0048146//positive regulation of fibroblast proliferation;GO:0032206//positive regulation of telomere maintenance;GO:0031667//response to nutrient levels;GO:0045820//negative regulation of glycolytic process;GO:1905549//positive regulation of telomeric heterochromatin assembly","K11416//mono-ADP-ribosyltransferase sirtuin 6 [EC:2.4.2.31]","NP_001307988.1//NAD-dependent protein deacetylase sirtuin-6 isoform 4 [Homo sapiens];XP_016790192.1//PREDICTED: NAD-dependent protein deacetylase sirtuin-6 isoform X5 [Pan troglodytes];NP_001180214.1//NAD-dependent protein deacetylase sirtuin-6 isoform 2 [Homo sapiens];NP_001307989.1//NAD-dependent protein deacetylase sirtuin-6 isoform 5 [Homo sapiens];NP_057623.2//NAD-dependent protein deacetylase sirtuin-6 isoform 1 [Homo sapiens];XP_011822746.1//PREDICTED: NAD-dependent protein deacetylase sirtuin-6 isoform X4 [Mandrillus leucophaeus]","1//3;3//A2MP1;2//1"]
[401115,439,72.66,101.6,0.483667131244043,{"v":5.87814369919786E-6,"d":"5.88E-06"},"*",{"v":1.101002E-6,"d":"1.10E-06"},"C4orf48","NA","NA","NA","NA","NP_001161715.1//neuropeptide-like protein C4orf48 isoform 1 [Homo sapiens]","1//3;2//1"]
[389203,1021,8.3,11.6,0.482941563780647,0.022779547554535,"*",0.00869456,"SMIM20","NA","NA","NA","NA","XP_008950444.1//PREDICTED: LOW QUALITY PROTEIN: small integral membrane protein 20 [Pan paniscus]","1//3"]
[164633,3001,1.46,2.04,0.482600783091478,0.114281172802306,"*",0.054608,"CABP7","GO:0032588//trans-Golgi network membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0048471//perinuclear region of cytoplasm","GO:0005509//calcium ion binding","NA","K13152//U11/U12 small nuclear ribonucleoprotein 20 kDa protein","XP_017711107.1//PREDICTED: calcium-binding protein 7 [Rhinopithecus bieti]","2//1"]
[348262,1271,69.49,97.04,0.481774169577941,{"v":7.53245876099426e-16,"d":"7.53E-16"},"*",{"v":4.93236e-17,"d":"4.93E-17"},"MCRIP1","NA","NA","NA","K17566//protein phosphatase 1 regulatory subunit 27","XP_008954745.1//PREDICTED: protein FAM195B isoform X2 [Pan paniscus];XP_008011458.1//PREDICTED: protein FAM195B isoform X1 [Chlorocebus sabaeus];XP_017734734.1//PREDICTED: mapk-regulated corepressor-interacting protein 1 isoform X4 [Rhinopithecus bieti]","1//3;4;2//1"]
[10581,738,59.88,83.6,0.481428720909828,{"v":2.27852410596027E-8,"d":"2.28E-08"},"*",{"v":3.0154e-09,"d":"3.02E-09"},"IFITM2","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","NA","GO:0035456//response to interferon-beta;GO:0060337//type I interferon signaling pathway;GO:0051607//defense response to virus;GO:0046597//negative regulation of viral entry into host cell;GO:0035455//response to interferon-alpha;GO:0045071//negative regulation of viral genome replication;GO:0034341//response to interferon-gamma;GO:0006955//immune response;GO:0009615//response to virus","K06566//interferon induced transmembrane protein","NP_006426.2//interferon-induced transmembrane protein 2 [Homo sapiens]","2//1"]
[6320,1423,8.61,12.02,0.481351753314342,0.00468175885413417,"*",1.502946E-3,"CLEC11A","GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0008083//growth factor activity;GO:0030246//carbohydrate binding","GO:0001503//ossification;GO:0008284//positive regulation of cell proliferation","K17521//C-type lectin domain family 11 member A","XP_007995878.1//PREDICTED: C-type lectin domain family 11 member A [Chlorocebus sabaeus]","2//1"]
[126208,2039,56.03,78.18,0.4806000920591,{"v":4.12384603502825e-21,"d":"4.12E-21"},"*",{"v":1.827772e-22,"d":"1.83E-22"},"ZNF787","GO:0005581//collagen trimer;GO:0005604//basement membrane","GO:0005201//extracellular matrix structural constituent","NA","K09228//KRAB domain-containing zinc finger protein;K16628//collagen, type VII, alpha","XP_009465419.1//PREDICTED: zinc finger protein 629-like, partial [Nipponia nippon];NP_001338611.1//zinc finger protein 787 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[7483,4012,0.81,1.13,0.480328959530563,0.197497477754287,"*",0.1052644,"WNT9A","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix","GO:0048018//receptor ligand activity;GO:0005102//receptor binding;GO:0005109//frizzled binding","GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0072498//embryonic skeletal joint development;GO:0045597//positive regulation of cell differentiation;GO:0008285//negative regulation of cell proliferation;GO:0045165//cell fate commitment;GO:0030182//neuron differentiation;GO:0007267//cell-cell signaling;GO:0061303//cornea development in camera-type eye;GO:0035115//embryonic forelimb morphogenesis;GO:0061072//iris morphogenesis;GO:0071300//cellular response to retinoic acid;GO:0007093//mitotic cell cycle checkpoint;GO:0060070//canonical Wnt signaling pathway;GO:0032331//negative regulation of chondrocyte differentiation;GO:0048704//embryonic skeletal system morphogenesis;GO:0007275//multicellular organism development;GO:0045880//positive regulation of smoothened signaling pathway;GO:0016055//Wnt signaling pathway","K01064//wingless-type MMTV integration site family, member 9","NP_003386.1//protein Wnt-9a precursor [Homo sapiens]","3//A2MP1"]
[83475,1868,8.33,11.62,0.480221668038981,0.000516309536527514,"*",0.000136269,"DOHH","GO:0005829//cytosol","GO:0046872//metal ion binding;GO:0019135//deoxyhypusine monooxygenase activity","GO:0008612//peptidyl-lysine modification to peptidyl-hypusine","K06072//deoxyhypusine monooxygenase [EC:1.14.99.29]","NP_112594.1//deoxyhypusine hydroxylase [Homo sapiens]","1//3;4"]
[10195,1571,72.17,100.64,0.479732667453577,{"v":1.28299891282051e-20,"d":"1.28E-20"},"*",{"v":5.95156e-22,"d":"5.95E-22"},"ALG3","GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0000033//alpha-1,3-mannosyltransferase activity;GO:0052925//dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity","GO:0006486//protein glycosylation;GO:0006488//dolichol-linked oligosaccharide biosynthetic process","K03845//alpha-1,3-mannosyltransferase [EC:2.4.1.258]","NP_001006942.1//dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase isoform d [Homo sapiens];NP_005778.1//dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase isoform a [Homo sapiens]","2//1;5"]
[51079,557,93.43,130.25,0.479325599449479,{"v":2.19655761756829e-09,"d":"2.20E-09"},"*",{"v":2.56728e-10,"d":"2.57E-10"},"NDUFA13","GO:0016021//integral component of membrane","NA","NA","K11353//NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 13","EAW84826.1//NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 [Homo sapiens]",6]
[127579,2421,0.33,0.46,0.47916783669856,0.578682723272602,"*",0.421532,"DCST2","GO:0016021//integral component of membrane","NA","NA","K14315//nucleoporin NDC1;K06836//disintegrin and metalloproteinase domain-containing protein 15 [EC:3.4.24.-]","NP_653223.2//DC-STAMP domain-containing protein 2 [Homo sapiens]","2//1"]
[51063,1966,0.94,1.31,0.478834149859813,0.365188326117742,"*",0.226008,"CALHM2","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane","GO:0005261//cation channel activity","GO:0034220//ion transmembrane transport","K19739//calcium homeostasis modulator protein 2","NP_057000.2//calcium homeostasis modulator protein 2 [Homo sapiens]",4]
[56925,1132,9.55,13.3,0.477853607465441,0.00943924002186191,"*",0.00324352,"LXN","GO:0070062//extracellular exosome;GO:0005737//cytoplasm","GO:0008191//metalloendopeptidase inhibitor activity;GO:0008201//heparin binding","GO:0050965//detection of temperature stimulus involved in sensory perception of pain;GO:0006954//inflammatory response","NA","NP_064554.3//latexin [Homo sapiens]","3//A2MP1"]
[5441,925,310.66,432.63,0.477797215325592,{"v":1.07768315586207e-49,"d":"1.08E-49"},"*",{"v":1.565184e-51,"d":"1.57E-51"},"POLR2L","NA","GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0003677//DNA binding;GO:0008270//zinc ion binding","GO:0006351//transcription, DNA-templated","K03007//DNA-directed RNA polymerases I, II, and III subunit RPABC5","XP_017704120.1//PREDICTED: DNA-directed RNA polymerases I, II, and III subunit RPABC5 [Rhinopithecus bieti]",4]
[9348,5961,0.51,0.71,0.477321777533186,0.212857337497109,"*",0.11521,"NDST3","GO:0016021//integral component of membrane","GO:0042328//heparan sulfate N-acetylglucosaminyltransferase activity;GO:0016787//hydrolase activity;GO:0015016//[heparan sulfate]-glucosamine N-sulfotransferase activity","GO:0015014//heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process","K02578//heparan sulfate N-deacetylase/N-sulfotransferase NDST3 [EC:3.1.1.- 2.8.2.-]","XP_012500826.1//PREDICTED: bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 [Propithecus coquereli]","2//1"]
[10423,1925,67.17,93.51,0.477303626772771,{"v":2.88089042051282e-23,"d":"2.88E-23"},"*",{"v":1.125376e-24,"d":"1.13E-24"},"CDIPT","GO:0016020//membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0000139//Golgi membrane","GO:0030246//carbohydrate binding;GO:0003881//CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity;GO:0019992//diacylglycerol binding;GO:0043178//alcohol binding;GO:0030145//manganese ion binding","GO:0046341//CDP-diacylglycerol metabolic process;GO:0006661//phosphatidylinositol biosynthetic process","K00999//CDP-diacylglycerol--inositol 3-phosphatidyltransferase [EC:2.7.8.11]","NP_006310.1//CDP-diacylglycerol--inositol 3-phosphatidyltransferase isoform 1 [Homo sapiens];ELW66369.1//CDP-diacylglycerol--inositol 3-phosphatidyltransferase [Tupaia chinensis]","1//3;4"]
[22913,4788,36.85,51.29,0.477012951994886,{"v":6.69180441481481e-32,"d":"6.69E-32"},"*",{"v":1.69662E-33,"d":"1.70E-33"},"RALY","GO:0005634//nucleus;GO:0071013//catalytic step 2 spliceosome","GO:0003723//RNA binding;GO:0003712//transcription cofactor activity","GO:1903506//regulation of nucleic acid-templated transcription;GO:0000398//mRNA splicing, via spliceosome;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:2000188//regulation of cholesterol homeostasis","K12895//heterogeneous nuclear ribonucleoprotein C-like 2","NP_031393.2//RNA-binding protein Raly isoform 2 [Homo sapiens];NP_057951.1//RNA-binding protein Raly isoform 1 [Homo sapiens]","3//A2MP1;2//1"]
[84922,2679,18.4,25.6,0.476438043942987,{"v":1.93183841163793e-09,"d":"1.93E-09"},"*",{"v":2.24458E-10,"d":"2.24E-10"},"FIZ1","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_011909026.1//PREDICTED: flt3-interacting zinc finger protein 1 isoform X3 [Cercocebus atys]","2//1"]
[150684,731,26.55,36.92,0.475690691954258,0.000525418638787592,"*",0.0001389034,"COMMD1","GO:0070062//extracellular exosome;GO:0010008//endosome membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0031462//Cul2-RING ubiquitin ligase complex;GO:0005829//cytosol;GO:0055037//recycling endosome;GO:0005769//early endosome","GO:0042802//identical protein binding;GO:0070300//phosphatidic acid binding;GO:0042803//protein homodimerization activity;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0080025//phosphatidylinositol-3,5-bisphosphate binding;GO:0005507//copper ion binding;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding","GO:0043687//post-translational protein modification;GO:2000009//negative regulation of protein localization to cell surface;GO:0055070//copper ion homeostasis;GO:0032434//regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0031398//positive regulation of protein ubiquitination;GO:0006351//transcription, DNA-templated;GO:0006893//Golgi to plasma membrane transport;GO:1902306//negative regulation of sodium ion transmembrane transport;GO:0015031//protein transport;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0048227//plasma membrane to endosome transport","NA","NP_689729.1//COMM domain-containing protein 1 isoform 1 [Homo sapiens];XP_004029343.2//PREDICTED: COMM domain-containing protein 1 [Gorilla gorilla gorilla];XP_015289094.1//PREDICTED: COMM domain-containing protein 1 isoform X2 [Macaca fascicularis]","1//3;3//A2MP1"]
[11045,1284,1.46,2.03,0.475511358305159,0.432098966887417,"*",0.28592,"UPK1A","GO:0070062//extracellular exosome;GO:0005783//endoplasmic reticulum;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0016324//apical plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0042803//protein homodimerization activity","GO:0007166//cell surface receptor signaling pathway;GO:0051259//protein oligomerization;GO:0030855//epithelial cell differentiation","K17347//uroplakin-1","NP_008931.1//uroplakin-1a isoform 1 [Homo sapiens];NP_001268372.1//uroplakin-1a isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[55876,1642,3.39,4.71,0.474441786476439,0.0772869986341463,"*",0.0347148,"GSDMB","GO:0005829//cytosol;GO:0005886//plasma membrane","NA","GO:0012501//programmed cell death","K22142//gasdermin-B","NP_061000.2//gasdermin-B isoform 2 [Homo sapiens];NP_001159430.1//gasdermin-B isoform 3 [Homo sapiens];NP_001035936.1//gasdermin-B isoform 1 [Homo sapiens];NP_001159431.1//gasdermin-B isoform 4 [Homo sapiens]","1//3;2//1"]
[1564,2371,0.36,0.5,0.473931188332412,0.578732459647615,"*",0.421532,"CYP2D7","NA","GO:0020037//heme binding;GO:0005506//iron ion binding;GO:0070330//aromatase activity","NA","K17712//cytochrome P450 family 2 subfamily D polypeptide 6 [EC:1.14.14.1]","A0A087X1C5.1//PUTATIVE PSEUDOGENE: RecName: Full=Putative cytochrome P450 2D7","1//3"]
[29984,1150,10.6,14.72,0.473713406606451,0.00601220435379337,"*",0.00197446,"RHOD","GO:0016020//membrane;GO:0010008//endosome membrane;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005886//plasma membrane;GO:0005769//early endosome","GO:0005525//GTP binding;GO:0019901//protein kinase binding;GO:0003924//GTPase activity","GO:0006605//protein targeting;GO:0030032//lamellipodium assembly;GO:0030335//positive regulation of cell migration;GO:0045785//positive regulation of cell adhesion;GO:2000249//regulation of actin cytoskeleton reorganization;GO:0051893//regulation of focal adhesion assembly;GO:0007266//Rho protein signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0051017//actin filament bundle assembly;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0048041//focal adhesion assembly","K07530//Ras homolog gene family, member D","NP_001287815.1//rho-related GTP-binding protein RhoD isoform 2 [Homo sapiens];NP_055393.1//rho-related GTP-binding protein RhoD isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[9945,3115,10.45,14.51,0.4735445770985,{"v":1.72758868171886E-6,"d":"1.73E-06"},"*",{"v":2.9698E-7,"d":"2.97E-07"},"GFPT2","GO:0005829//cytosol","GO:0097367//carbohydrate derivative binding;GO:0004360//glutamine-fructose-6-phosphate transaminase (isomerizing) activity","GO:0006047//UDP-N-acetylglucosamine metabolic process;GO:1901137//carbohydrate derivative biosynthetic process;GO:0006541//glutamine metabolic process;GO:1990830//cellular response to leukemia inhibitory factor;GO:0006002//fructose 6-phosphate metabolic process;GO:0006112//energy reserve metabolic process;GO:0006487//protein N-linked glycosylation;GO:0006048//UDP-N-acetylglucosamine biosynthetic process","K00820//glucosamine---fructose-6-phosphate aminotransferase (isomerizing) [EC:2.6.1.16]","XP_017372785.1//PREDICTED: glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 [Cebus capucinus imitator]","3//A2MP1"]
[6385,2615,20.27,28.14,0.473276239769634,{"v":6.03656822133485e-10,"d":"6.04E-10"},"*",{"v":6.62458e-11,"d":"6.62E-11"},"SDC4","GO:0070062//extracellular exosome;GO:0005925//focal adhesion;GO:0043034//costamere;GO:0005796//Golgi lumen;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0045121//membrane raft;GO:0016021//integral component of membrane;GO:0043202//lysosomal lumen;GO:0005886//plasma membrane","GO:0005080//protein kinase C binding;GO:0042802//identical protein binding;GO:0001968//fibronectin binding;GO:0070053//thrombospondin receptor activity","GO:1903543//positive regulation of exosomal secretion;GO:0016477//cell migration;GO:0010762//regulation of fibroblast migration;GO:0006024//glycosaminoglycan biosynthetic process;GO:0042130//negative regulation of T cell proliferation;GO:0045860//positive regulation of protein kinase activity;GO:0006027//glycosaminoglycan catabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0050900//leukocyte migration;GO:0051894//positive regulation of focal adhesion assembly;GO:0042060//wound healing;GO:0060122//inner ear receptor cell stereocilium organization;GO:0051496//positive regulation of stress fiber assembly;GO:0001523//retinoid metabolic process;GO:0001843//neural tube closure;GO:0001657//ureteric bud development;GO:1903553//positive regulation of extracellular exosome assembly","K16338//syndecan 4","NP_002990.2//syndecan-4 precursor [Homo sapiens]","3//A2MP1"]
[549,1598,3.4,4.72,0.473252113224139,0.102001281967651,"*",0.0477696,"AUH","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0004490//methylglutaconyl-CoA hydratase activity;GO:0003730//mRNA 3'-UTR binding;GO:0004300//enoyl-CoA hydratase activity","GO:0006635//fatty acid beta-oxidation;GO:0009083//branched-chain amino acid catabolic process;GO:0008152//metabolic process;GO:0006552//leucine catabolic process","K05607//methylglutaconyl-CoA hydratase [EC:4.2.1.18]","NP_001689.1//methylglutaconyl-CoA hydratase, mitochondrial isoform 1 precursor [Homo sapiens];NP_001293119.1//methylglutaconyl-CoA hydratase, mitochondrial isoform 2 [Homo sapiens];XP_005252123.1//PREDICTED: methylglutaconyl-CoA hydratase, mitochondrial isoform X1 [Homo sapiens];XP_016870338.1//PREDICTED: methylglutaconyl-CoA hydratase, mitochondrial isoform X3 [Homo sapiens]","1//3;2//1"]
[26648,1020,18.97,26.33,0.472987842634587,0.000420847971987443,"*",1.09098E-4,"OR7E24","NA","NA","NA","K04257//olfactory receptor","XP_010387160.1//PREDICTED: olfactory receptor 7E24 [Rhinopithecus roxellana]","1//3"]
[27344,1071,39.47,54.78,0.472892746812275,{"v":6.45898373901465e-08,"d":"6.46E-08"},"*",{"v":9.10986e-09,"d":"9.11E-09"},"PCSK1N","GO:0070062//extracellular exosome;GO:0030141//secretory granule;GO:0005615//extracellular space;GO:0005802//trans-Golgi network","GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005102//receptor binding;GO:0004866//endopeptidase inhibitor activity","GO:0016486//peptide hormone processing;GO:0009409//response to cold;GO:0002021//response to dietary excess;GO:0007218//neuropeptide signaling pathway","K03129//transcription initiation factor TFIID subunit 4;K15176//RNA polymerase-associated protein CTR9;K17498//transcription factor SPN1","NP_037403.1//proSAAS preproprotein [Homo sapiens]",4]
[349565,2128,0.49,0.68,0.472752997135131,0.529517010809853,"*",0.374116,"NMNAT3","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0000309//nicotinamide-nucleotide adenylyltransferase activity;GO:0005524//ATP binding;GO:0016779//nucleotidyltransferase activity;GO:0004515//nicotinate-nucleotide adenylyltransferase activity","GO:0009611//response to wounding;GO:0034628//'de novo' NAD biosynthetic process from aspartate;GO:0009058//biosynthetic process;GO:0019674//NAD metabolic process;GO:0009435//NAD biosynthetic process","K06210//nicotinamide mononucleotide adenylyltransferase [EC:2.7.7.1 2.7.7.18]","XP_008007113.1//PREDICTED: nicotinamide mononucleotide adenylyltransferase 3 isoform X3 [Chlorocebus sabaeus];NP_001307439.1//nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 isoform 3 [Homo sapiens];NP_001307440.1//nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 isoform 4 [Homo sapiens]","4;1//3;2//1"]
[4830,818,481.16,667.73,0.472748146824813,{"v":7.98108446709677e-65,"d":"7.98E-65"},"*",{"v":7.74426e-67,"d":"7.74E-67"},"NME1","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0043209//myelin sheath;GO:0005813//centrosome;GO:0032587//ruffle membrane;GO:0005741//mitochondrial outer membrane;GO:0005882//intermediate filament;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0005829//cytosol","GO:0000287//magnesium ion binding;GO:0003723//RNA binding;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0004536//deoxyribonuclease activity;GO:0043024//ribosomal small subunit binding;GO:0019215//intermediate filament binding;GO:0004550//nucleoside diphosphate kinase activity;GO:0019901//protein kinase binding;GO:0003697//single-stranded DNA binding;GO:0043015//gamma-tubulin binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0005525//GTP binding","GO:0007595//lactation;GO:0035690//cellular response to drug;GO:0021766//hippocampus development;GO:0002762//negative regulation of myeloid leukocyte differentiation;GO:0010629//negative regulation of gene expression;GO:0015949//nucleobase-containing small molecule interconversion;GO:0071398//cellular response to fatty acid;GO:0033574//response to testosterone;GO:0006897//endocytosis;GO:0043388//positive regulation of DNA binding;GO:0008285//negative regulation of cell proliferation;GO:0014075//response to amine;GO:0006241//CTP biosynthetic process;GO:0051591//response to cAMP;GO:0010976//positive regulation of neuron projection development;GO:0006228//UTP biosynthetic process;GO:0071333//cellular response to glucose stimulus;GO:0042981//regulation of apoptotic process;GO:0006183//GTP biosynthetic process;GO:0050679//positive regulation of epithelial cell proliferation","K00940//nucleoside-diphosphate kinase [EC:2.7.4.6]","NP_937818.1//nucleoside diphosphate kinase A isoform a [Homo sapiens];CAA35621.1//Nm23 protein, partial [Homo sapiens]","1//3;2//1"]
[51526,2260,16.79,23.3,0.472727724604613,{"v":2.36150948552523e-07,"d":"2.36E-07"},"*",{"v":3.57464e-08,"d":"3.57E-08"},"OSER1","NA","NA","NA","NA","XP_011784404.1//PREDICTED: oxidative stress-responsive serine-rich protein 1 isoform X1 [Colobus angolensis palliatus]",7]
[8527,6294,21.57,29.93,0.472566102337647,{"v":2.22356539099678E-23,"d":"2.22E-23"},"*",{"v":8.65818e-25,"d":"8.66E-25"},"DGKD","GO:0005634//nucleus;GO:0005829//cytosol;GO:0031410//cytoplasmic vesicle;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0004143//diacylglycerol kinase activity;GO:0003951//NAD+ kinase activity;GO:0046872//metal ion binding;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity;GO:0019992//diacylglycerol binding;GO:0042803//protein homodimerization activity","GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0007165//signal transduction;GO:0035556//intracellular signal transduction;GO:0051260//protein homooligomerization;GO:0030168//platelet activation;GO:0016049//cell growth;GO:0019932//second-messenger-mediated signaling;GO:0010033//response to organic substance;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007275//multicellular organism development;GO:0006897//endocytosis;GO:0015031//protein transport;GO:0046339//diacylglycerol metabolic process;GO:0046834//lipid phosphorylation","K00901//diacylglycerol kinase (ATP) [EC:2.7.1.107]","NP_003639.2//diacylglycerol kinase delta isoform 1 [Homo sapiens];NP_690618.2//diacylglycerol kinase delta isoform 2 [Homo sapiens]","2//1"]
[51303,945,30.92,42.89,0.472100996710709,0.000143639115518148,"*",{"v":3.41878e-05,"d":"3.42E-05"},"FKBP11","GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005737//cytoplasm","GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005528//FK506 binding","GO:0061077//chaperone-mediated protein folding","K09576//FK506-binding protein 11 [EC:5.2.1.8]","NP_057678.1//peptidyl-prolyl cis-trans isomerase FKBP11 isoform 1 precursor [Homo sapiens];XP_011791609.1//PREDICTED: peptidyl-prolyl cis-trans isomerase FKBP11 isoform X2 [Colobus angolensis palliatus];NP_001137254.1//peptidyl-prolyl cis-trans isomerase FKBP11 isoform 3 precursor [Homo sapiens]","1//3;2//1"]
[93343,1443,21.06,29.21,0.471956921803462,{"v":3.4134842004102e-05,"d":"3.41E-05"},"*",{"v":7.29324e-06,"d":"7.29E-06"},"MVB12A","GO:0043657//host cell;GO:0070062//extracellular exosome;GO:0010008//endosome membrane;GO:0005654//nucleoplasm;GO:0031902//late endosome membrane;GO:0000813//ESCRT I complex;GO:0005813//centrosome;GO:0031982//vesicle;GO:0005829//cytosol;GO:0005794//Golgi apparatus","GO:0008289//lipid binding;GO:0043130//ubiquitin binding;GO:0017124//SH3 domain binding","GO:0016197//endosomal transport;GO:0019075//virus maturation;GO:0048524//positive regulation of viral process;GO:0019058//viral life cycle;GO:0039702//viral budding via host ESCRT complex;GO:0036258//multivesicular body assembly;GO:1903772//regulation of viral budding via host ESCRT complex;GO:0042058//regulation of epidermal growth factor receptor signaling pathway;GO:0075733//intracellular transport of virus;GO:0015031//protein transport;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0016236//macroautophagy","K12186//ESCRT-I complex subunit MVB12","XP_002828938.1//PREDICTED: multivesicular body subunit 12A [Pongo abelii];XP_011781145.1//PREDICTED: multivesicular body subunit 12A isoform X2 [Colobus angolensis palliatus]","1//3;3//A2MP1"]
[7461,5461,9.82,13.62,0.471931773697378,{"v":3.60157823868313e-10,"d":"3.60E-10"},"*",{"v":3.83516e-11,"d":"3.84E-11"},"CLIP2","GO:0005875//microtubule associated complex;GO:0035371//microtubule plus-end;GO:0005881//cytoplasmic microtubule","GO:0051010//microtubule plus-end binding;GO:0008017//microtubule binding","NA","K10422//CAP-Gly domain-containing linker protein 2","NP_003379.3//CAP-Gly domain-containing linker protein 2 isoform 1 [Homo sapiens];NP_115797.1//CAP-Gly domain-containing linker protein 2 isoform 2 [Homo sapiens]","4;2//1"]
[222166,5814,1.06,1.47,0.471751890273165,0.0620631888537777,"*",0.0270492,"MTURN","NA","NA","NA","K10582//ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]","XP_007979925.1//PREDICTED: maturin [Chlorocebus sabaeus]","2//1"]
[388963,2142,3.83,5.31,0.471367468879196,0.0339260962332398,"*",0.01362226,"C2orf81","NA","NA","NA","K22020//mucin-19;K13172//serine/arginine repetitive matrix protein 2;K17501//protein phosphatase 1E [EC:3.1.3.16];K05626//atrophin-1 (dentatorubral-pallidoluysian atrophy protein);K19720//collagen, type III, alpha","NP_001138526.1//uncharacterized protein C2orf81 isoform 4 [Homo sapiens];NP_001303693.1//uncharacterized protein C2orf81 isoform 1 [Homo sapiens];NP_001303694.1//uncharacterized protein C2orf81 isoform 2 [Homo sapiens]","1//3"]
[386724,3008,2.33,3.23,0.471204210039645,0.0439907544411058,"*",0.01832994,"AMIGO3","GO:0016021//integral component of membrane","NA","GO:0051965//positive regulation of synapse assembly;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules","K10730//ATP-dependent DNA helicase Q4 [EC:3.6.4.12];K12169//Kip1 ubiquitination-promoting complex protein 1 [EC:2.3.2.27]","NP_942015.1//amphoterin-induced protein 3 precursor [Homo sapiens]","2//1"]
[118813,2761,11.65,16.15,0.471204210039644,{"v":1.508374782172e-05,"d":"1.51E-05"},"*",{"v":3.00844e-06,"d":"3.01E-06"},"ZFYVE27","GO:0032584//growth cone membrane;GO:0071782//endoplasmic reticulum tubular network;GO:0030425//dendrite;GO:0030424//axon;GO:0055038//recycling endosome membrane;GO:0005783//endoplasmic reticulum;GO:0030176//integral component of endoplasmic reticulum membrane","GO:0046872//metal ion binding;GO:0043621//protein self-association","GO:0045773//positive regulation of axon extension;GO:0072659//protein localization to plasma membrane;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0071787//endoplasmic reticulum tubular network formation;GO:0031175//neuron projection development;GO:0016192//vesicle-mediated transport","K19368//protrudin","XP_005269562.1//PREDICTED: protrudin isoform X3 [Homo sapiens];EAW49902.1//zinc finger, FYVE domain containing 27, isoform CRA_h [Homo sapiens];XP_007961961.1//PREDICTED: protrudin isoform X7 [Chlorocebus sabaeus];NP_001002261.1//protrudin isoform a [Homo sapiens];NP_653189.3//protrudin isoform b [Homo sapiens]","6;1//3;3//A2MP1"]
[100128242,1004,1.89,2.62,0.471180577316378,0.365151389905937,"*",0.226008,"LOC100128242","NA","NA","NA","K13172//serine/arginine repetitive matrix protein 2","XP_012351215.1//PREDICTED: uncharacterized protein LOC105737566 [Nomascus leucogenys]","1//3"]
[840,2415,7.88,10.92,0.470705321463476,0.00211382679219962,"*",0.000631078,"CASP7","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0097153//cysteine-type endopeptidase activity involved in apoptotic process;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0004197//cysteine-type endopeptidase activity;GO:0004190//aspartic-type endopeptidase activity;GO:0097200//cysteine-type endopeptidase activity involved in execution phase of apoptosis","GO:0051402//neuron apoptotic process;GO:0009411//response to UV;GO:0007507//heart development;GO:0007568//aging;GO:0006915//apoptotic process;GO:0097194//execution phase of apoptosis;GO:0006508//proteolysis;GO:0016485//protein processing;GO:0008635//activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c;GO:0072734//cellular response to staurosporine","K04397//caspase 7 [EC:3.4.22.60]","XP_007962308.1//PREDICTED: caspase-7 isoform X1 [Chlorocebus sabaeus];XP_001148847.3//PREDICTED: caspase-7 isoform X7 [Pan troglodytes];NP_203124.1//caspase-7 isoform delta [Homo sapiens];NP_001253986.1//caspase-7 isoform e [Homo sapiens];NP_203126.1//caspase-7 isoform beta [Homo sapiens]","4;1//3;3//A2MP1;5"]
[57057,1824,0.13,0.18,0.46948528330122,0.810953076664331,"*",0.724446,"TBX20","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0001105//RNA polymerase II transcription coactivator activity;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0001102//RNA polymerase II activating transcription factor binding;GO:0003700//DNA binding transcription factor activity","GO:0003148//outflow tract septum morphogenesis;GO:0003344//pericardium morphogenesis;GO:0021524//visceral motor neuron differentiation;GO:0010991//negative regulation of SMAD protein complex assembly;GO:0003143//embryonic heart tube morphogenesis;GO:0001706//endoderm formation;GO:0060577//pulmonary vein morphogenesis;GO:0036306//embryonic heart tube elongation;GO:0003272//endocardial cushion formation;GO:0003279//cardiac septum development;GO:0003193//pulmonary valve formation;GO:0055008//cardiac muscle tissue morphogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0003203//endocardial cushion morphogenesis;GO:0035922//foramen ovale closure;GO:0003215//cardiac right ventricle morphogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0009953//dorsal/ventral pattern formation;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0006936//muscle contraction;GO:0048370//lateral mesoderm formation;GO:0006351//transcription, DNA-templated;GO:0001947//heart looping;GO:0003207//cardiac chamber formation;GO:0008015//blood circulation;GO:0001764//neuron migration;GO:0060413//atrial septum morphogenesis;GO:0003180//aortic valve morphogenesis;GO:0003175//tricuspid valve development;GO:0001569//branching involved in blood vessel morphogenesis","K10185//T-box protein 20","XP_014920543.1//PREDICTED: T-box transcription factor TBX20 [Acinonyx jubatus];NP_001071121.1//T-box transcription factor TBX20 isoform 1 [Homo sapiens]","1//3;2//1"]
[64080,1391,3.64,5.04,0.46948528330122,0.183356089513823,"*",0.0963268,"RBKS","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0019200//carbohydrate kinase activity;GO:0005524//ATP binding;GO:0004747//ribokinase activity","GO:0046835//carbohydrate phosphorylation;GO:0006098//pentose-phosphate shunt;GO:0019303//D-ribose catabolic process","K00852//ribokinase [EC:2.7.1.15]","NP_071411.1//ribokinase isoform 1 [Homo sapiens]","1//3;2//1"]
[280,2253,0.26,0.36,0.46948528330122,0.634316395348837,"*",0.4781,"AMY2B","GO:0070062//extracellular exosome","GO:0043169//cation binding;GO:0046872//metal ion binding;GO:0004556//alpha-amylase activity;GO:0103025//alpha-amylase activity (releasing maltohexaose)","GO:0007586//digestion;GO:0005975//carbohydrate metabolic process","K01176//alpha-amylase [EC:3.2.1.1]","NP_066188.1//alpha-amylase 2B precursor [Homo sapiens]",4]
[4602,3220,0.13,0.18,0.46948528330122,0.695373745711706,"*",0.578622,"MYB","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016363//nuclear matrix","GO:0003677//DNA binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0001135//transcription factor activity, RNA polymerase II transcription factor recruiting","GO:0060252//positive regulation of glial cell proliferation;GO:0000278//mitotic cell cycle;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0032967//positive regulation of collagen biosynthetic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:2000491//positive regulation of hepatic stellate cell activation;GO:0070301//cellular response to hydrogen peroxide;GO:0045892//negative regulation of transcription, DNA-templated;GO:0051571//positive regulation of histone H3-K4 methylation;GO:0043525//positive regulation of neuron apoptotic process;GO:0045624//positive regulation of T-helper cell differentiation;GO:0051574//positive regulation of histone H3-K9 methylation;GO:0001666//response to hypoxia;GO:0071300//cellular response to retinoic acid;GO:1904899//positive regulation of hepatic stellate cell proliferation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0071636//positive regulation of transforming growth factor beta production;GO:1902036//regulation of hematopoietic stem cell differentiation;GO:2000845//positive regulation of testosterone secretion","K09420//transcriptional activator Myb","NP_001155128.1//transcriptional activator Myb isoform 4 [Homo sapiens];NP_001155130.1//transcriptional activator Myb isoform 6 [Homo sapiens];NP_001155132.1//transcriptional activator Myb isoform 8 [Homo sapiens];NP_001155129.1//transcriptional activator Myb isoform 5 [Homo sapiens];NP_001123645.1//transcriptional activator Myb isoform 1 [Homo sapiens];CAE82649.1//v-myb myeloblastosis viral oncogene homologue (avian), partial [Homo sapiens]","1//3;3//A2MP1"]
[30818,2735,0.73,1.01,0.468386923871777,0.386065451168364,"*",0.242022,"KCNIP3","GO:0030425//dendrite;GO:0030424//axon;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0043679//axon terminus;GO:0032993//protein-DNA complex;GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex","GO:0005244//voltage-gated ion channel activity;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0015459//potassium channel regulator activity;GO:0005267//potassium channel activity;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0044325//ion channel binding;GO:0005509//calcium ion binding","GO:0006886//intracellular protein transport;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0061337//cardiac conduction;GO:0007165//signal transduction;GO:0072659//protein localization to plasma membrane;GO:0006351//transcription, DNA-templated;GO:1901379//regulation of potassium ion transmembrane transport;GO:0006915//apoptotic process","K19932//neuronal calcium sensor 1;K16575//centractin","NP_038462.1//calsenilin isoform 1 [Homo sapiens];NP_001030086.1//calsenilin isoform 2 precursor [Homo sapiens]","4;1//3"]
[56654,1548,48.07,66.5,0.468217537138019,{"v":3.73687502560124e-13,"d":"3.74E-13"},"*",{"v":3.01542e-14,"d":"3.02E-14"},"NPDC1","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","NA","GO:0050776//regulation of immune response","K09367//POU domain transcription factor, class 5;K14676//lysophospholipid hydrolase [EC:3.1.1.5];K01509//adenosinetriphosphatase [EC:3.6.1.3]","NP_056207.3//neural proliferation differentiation and control protein 1 precursor [Homo sapiens]","3//A2MP1"]
[29085,1221,77.42,107.08,0.467910831348467,{"v":6.54247641233141e-16,"d":"6.54E-16"},"*",{"v":4.25134e-17,"d":"4.25E-17"},"PHPT1","GO:0070062//extracellular exosome;GO:0005829//cytosol","GO:0044325//ion channel binding;GO:0101006//protein histidine phosphatase activity;GO:0019855//calcium channel inhibitor activity;GO:0004721//phosphoprotein phosphatase activity","GO:2000984//negative regulation of ATP citrate synthase activity;GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:2000249//regulation of actin cytoskeleton reorganization;GO:0051350//negative regulation of lyase activity;GO:0050860//negative regulation of T cell receptor signaling pathway;GO:2000147//positive regulation of cell motility;GO:0006470//protein dephosphorylation;GO:0035971//peptidyl-histidine dephosphorylation","K01112//phosphohistidine phosphatase [EC:3.9.1.3]","NP_001129333.1//14 kDa phosphohistidine phosphatase isoform 2 [Homo sapiens];NP_001274272.1//14 kDa phosphohistidine phosphatase isoform 5 [Homo sapiens];XP_005580449.1//PREDICTED: 14 kDa phosphohistidine phosphatase isoform X6 [Macaca fascicularis]","1//3;2//1;5"]
[4733,1467,29.83,41.25,0.467630141685328,{"v":4.40727157674841e-08,"d":"4.41E-08"},"*",{"v":6.07538e-09,"d":"6.08E-09"},"DRG1","GO:0016020//membrane;GO:0016604//nuclear body;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005844//polysome","GO:0042802//identical protein binding;GO:0005525//GTP binding;GO:0008134//transcription factor binding","GO:0007275//multicellular organism development;GO:0006351//transcription, DNA-templated","K06944//uncharacterized protein","XP_015289556.1//PREDICTED: LOW QUALITY PROTEIN: developmentally-regulated GTP-binding protein 1-like [Macaca fascicularis]","3//A2MP1"]
[55132,2440,3.58,4.95,0.467468937702716,0.0835655993376569,"*",0.0379116,"LARP1B","GO:0005634//nucleus;GO:0030529//intracellular ribonucleoprotein complex;GO:0019013//viral nucleocapsid","GO:0003723//RNA binding","NA","K18757//la-related protein 1","XP_016863828.1//PREDICTED: la-related protein 1B isoform X5 [Homo sapiens];XP_011530366.2//PREDICTED: la-related protein 1B isoform X10 [Homo sapiens];XP_016863841.1//PREDICTED: la-related protein 1B isoform X27 [Homo sapiens];NP_115615.2//la-related protein 1B isoform 3 [Homo sapiens];XP_016863837.1//PREDICTED: la-related protein 1B isoform X23 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[79603,1817,3.46,4.78,0.466238580344024,0.0620721046976009,"*",0.0270492,"CERS4","GO:0005634//nucleus;GO:0031965//nuclear membrane;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0003677//DNA binding;GO:0050291//sphingosine N-acyltransferase activity","GO:0030148//sphingolipid biosynthetic process;GO:0046513//ceramide biosynthetic process","K04710//ceramide synthetase [EC:2.3.1.24]","NP_078828.2//ceramide synthase 4 [Homo sapiens]","2//1"]
[254427,3360,5.82,8.04,0.466176348270644,0.000359468976787463,"*",{"v":9.19038e-05,"d":"9.19E-05"},"PROSER2","NA","NA","NA","K16628//collagen, type VII, alpha;K22022//mucin-21","NP_694988.3//proline and serine-rich protein 2 [Homo sapiens]","3//A2MP1"]
[23640,1722,86.73,119.81,0.466145313747691,{"v":2.81855357205882e-25,"d":"2.82E-25"},"*",{"v":9.59868e-27,"d":"9.60E-27"},"HSPBP1","NA","GO:0004857//enzyme inhibitor activity","GO:0006457//protein folding;GO:0031398//positive regulation of protein ubiquitination;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process","K09562//hsp70-interacting protein","NP_001284529.1//hsp70-binding protein 1 isoform 1 [Homo sapiens]","4;1//3"]
[440822,3481,0.5,0.69,0.464668267003444,0.344849694341181,"*",0.20906,"PIWIL3","GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0003676//nucleic acid binding","GO:0030154//cell differentiation;GO:0007275//multicellular organism development;GO:0051321//meiotic cell cycle;GO:0031047//gene silencing by RNA;GO:0007283//spermatogenesis;GO:0006417//regulation of translation","K02156//aubergine","NP_001242904.1//piwi-like protein 3 isoform 2 [Homo sapiens];NP_001008496.2//piwi-like protein 3 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[1514,1630,362.42,499.83,0.463774923047926,{"v":5.02927295294118e-95,"d":"5.03E-95"},"*",{"v":3.21138e-97,"d":"3.21E-97"},"CTSL","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0043202//lysosomal lumen;GO:0005576//extracellular region;GO:0005764//lysosome;GO:0036021//endolysosome lumen","GO:0004252//serine-type endopeptidase activity;GO:0042393//histone binding;GO:0001968//fibronectin binding;GO:0043394//proteoglycan binding;GO:0097655//serpin family protein binding;GO:0005518//collagen binding;GO:0008234//cysteine-type peptidase activity;GO:0004197//cysteine-type endopeptidase activity","GO:0019882//antigen processing and presentation;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0071888//macrophage apoptotic process;GO:0002224//toll-like receptor signaling pathway;GO:0002250//adaptive immune response;GO:0022617//extracellular matrix disassembly;GO:0045616//regulation of keratinocyte differentiation;GO:0006508//proteolysis;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0097067//cellular response to thyroid hormone stimulus;GO:0030574//collagen catabolic process","K01365//cathepsin L [EC:3.4.22.15]","AAH12612.1//Cathepsin L1 [Homo sapiens];NP_001903.1//cathepsin L1 isoform 1 preproprotein [Homo sapiens]","4;1//3;2//1"]
[9296,749,266.16,367.01,0.463525601691093,{"v":3.50548829473684E-32,"d":"3.51E-32"},"*",{"v":8.75604e-34,"d":"8.76E-34"},"ATP6V1F","NA","NA","NA","K02151//V-type H+-transporting ATPase subunit F","XP_011794960.1//PREDICTED: V-type proton ATPase subunit F isoform X2 [Colobus angolensis palliatus];XP_011794959.1//PREDICTED: V-type proton ATPase subunit F isoform X1 [Colobus angolensis palliatus]","1//3;3//A2MP1"]
[7593,2693,10.12,13.95,0.46305583202224,{"v":5.52860683333333e-05,"d":"5.53E-05"},"*",{"v":1.221042e-05,"d":"1.22E-05"},"MZF1","GO:0005634//nucleus","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0042803//protein homodimerization activity;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding","NA","K09228//KRAB domain-containing zinc finger protein;K09229//KRAB and SCAN domains-containing zinc finger protein","XP_006940776.1//PREDICTED: myeloid zinc finger 1 isoform X4 [Felis catus]","1//3;2//1"]
[4794,2581,3.12,4.3,0.462790630727212,0.0339313864400437,"*",0.01362226,"NFKBIE","GO:0005634//nucleus;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0001650//fibrillar center;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm","NA","GO:0042994//cytoplasmic sequestering of transcription factor;GO:0042942//D-serine transport","K05872//NF-kappa-B inhibitor epsilon","NP_004547.2//NF-kappa-B inhibitor epsilon [Homo sapiens]","2//1"]
[8740,4406,0.82,1.13,0.462626957797104,0.187968364325477,"*",0.09935,"TNFSF14","GO:0005615//extracellular space;GO:0005622//intracellular;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0005164//tumor necrosis factor receptor binding;GO:0005125//cytokine activity;GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process;GO:0042802//identical protein binding;GO:0005102//receptor binding","GO:0042110//T cell activation;GO:0010820//positive regulation of T cell chemotaxis;GO:0007165//signal transduction;GO:0071260//cellular response to mechanical stimulus;GO:0008588//release of cytoplasmic sequestered NF-kappaB;GO:0031295//T cell costimulation;GO:0006915//apoptotic process;GO:0043029//T cell homeostasis;GO:0042098//T cell proliferation;GO:0006955//immune response;GO:0045663//positive regulation of myoblast differentiation;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:1901741//positive regulation of myoblast fusion","K05477//tumor necrosis factor ligand superfamily member 14","NP_742011.2//tumor necrosis factor ligand superfamily member 14 isoform 2 [Homo sapiens];NP_003798.2//tumor necrosis factor ligand superfamily member 14 isoform 1 [Homo sapiens]","4;3//A2MP1"]
[2627,3785,0.9,1.24,0.4623432140572,0.208336602161534,"*",0.1122284,"GATA6","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0005667//transcription factor complex","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0001103//RNA polymerase II repressing transcription factor binding;GO:0044212//transcription regulatory region DNA binding;GO:0003705//transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0019901//protein kinase binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0008270//zinc ion binding;GO:0008134//transcription factor binding;GO:0003700//DNA binding transcription factor activity","GO:0003148//outflow tract septum morphogenesis;GO:0007596//blood coagulation;GO:0030513//positive regulation of BMP signaling pathway;GO:0043627//response to estrogen;GO:0051891//positive regulation of cardioblast differentiation;GO:0032912//negative regulation of transforming growth factor beta2 production;GO:0003309//type B pancreatic cell differentiation;GO:0008584//male gonad development;GO:0044267//cellular protein metabolic process;GO:0032911//negative regulation of transforming growth factor beta1 production;GO:0045766//positive regulation of angiogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0060486//Clara cell differentiation;GO:0042493//response to drug;GO:0055007//cardiac muscle cell differentiation;GO:0110024//positive regulation of cardiac muscle myoblast proliferation;GO:0043066//negative regulation of apoptotic process;GO:0060575//intestinal epithelial cell differentiation;GO:0070848//response to growth factor;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0071773//cellular response to BMP stimulus;GO:0071456//cellular response to hypoxia;GO:0014898//cardiac muscle hypertrophy in response to stress;GO:0035239//tube morphogenesis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0071371//cellular response to gonadotropin stimulus;GO:0060510//Type II pneumocyte differentiation;GO:0048645//animal organ formation;GO:0007493//endodermal cell fate determination;GO:0060430//lung saccule development;GO:0001889//liver development;GO:0003310//pancreatic A cell differentiation;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0060947//cardiac vascular smooth muscle cell differentiation;GO:0001701//in utero embryonic development;GO:0006366//transcription from RNA polymerase II promoter;GO:0051145//smooth muscle cell differentiation;GO:0071158//positive regulation of cell cycle arrest;GO:0006644//phospholipid metabolic process","K17897//GATA-binding protein 6","NP_005248.2//transcription factor GATA-6 [Homo sapiens]",5]
[652968,1644,6.09,8.39,0.462228582533491,0.0161428015149957,"*",0.00589666,"CASTOR1","GO:0005829//cytosol;GO:0061700//GATOR2 complex","GO:0034618//arginine binding;GO:0042802//identical protein binding","GO:1903577//cellular response to L-arginine;GO:1903432//regulation of TORC1 signaling;GO:1904262//negative regulation of TORC1 signaling","K19944//TBC1 domain family member 10","XP_003317231.2//PREDICTED: GATS-like protein 3 isoform X2 [Pan troglodytes]","2//1"]
[10938,3438,36.99,50.94,0.461663659150199,{"v":5.03638588541667E-20,"d":"5.04E-20"},"*",{"v":2.4214e-21,"d":"2.42E-21"},"EHD1","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0010008//endosome membrane;GO:0043209//myelin sheath;GO:0048471//perinuclear region of cytoplasm;GO:0055038//recycling endosome membrane;GO:0031901//early endosome membrane;GO:0031095//platelet dense tubular network membrane;GO:0030139//endocytic vesicle;GO:0005811//lipid droplet;GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0020018//ciliary pocket membrane","GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0005509//calcium ion binding;GO:0005525//GTP binding;GO:0017137//Rab GTPase binding;GO:0045296//cadherin binding","GO:0016197//endosomal transport;GO:0034383//low-density lipoprotein particle clearance;GO:0007596//blood coagulation;GO:2001137//positive regulation of endocytic recycling;GO:0061512//protein localization to cilium;GO:0051260//protein homooligomerization;GO:1990090//cellular response to nerve growth factor stimulus;GO:0006886//intracellular protein transport;GO:0060271//cilium assembly;GO:0010886//positive regulation of cholesterol storage;GO:0031175//neuron projection development;GO:0042632//cholesterol homeostasis;GO:0006897//endocytosis;GO:0032456//endocytic recycling;GO:1901741//positive regulation of myoblast fusion","K12483//EH domain-containing protein 1","NP_001269374.1//EH domain-containing protein 1 isoform 2 [Homo sapiens];XP_010994338.1//PREDICTED: EH domain-containing protein 1 [Camelus dromedarius]","1//3;3//A2MP1"]
[57085,1187,48.18,66.35,0.461662072019085,{"v":2.25622892474413e-10,"d":"2.26E-10"},"*",{"v":2.34606E-11,"d":"2.35E-11"},"AGTRAP","GO:0043231//intracellular membrane-bounded organelle;GO:0005654//nucleoplasm;GO:0005938//cell cortex;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0000139//Golgi membrane;GO:0030659//cytoplasmic vesicle membrane","GO:0004945//angiotensin type II receptor activity","GO:0008217//regulation of blood pressure;GO:0038166//angiotensin-activated signaling pathway;GO:0001666//response to hypoxia","K14435//chromodomain-helicase-DNA-binding protein 5 [EC:3.6.4.12]","XP_011540101.2//PREDICTED: type-1 angiotensin II receptor-associated protein isoform X3 [Homo sapiens];NP_001035286.1//type-1 angiotensin II receptor-associated protein isoform d [Homo sapiens];NP_065083.3//type-1 angiotensin II receptor-associated protein isoform a [Homo sapiens];NP_001035284.1//type-1 angiotensin II receptor-associated protein isoform b [Homo sapiens]","1//3;4"]
[1258,5208,0.61,0.84,0.461580085215874,0.170566607967166,"*",0.0884546,"CNGB1","GO:0060170//ciliary membrane;GO:0043195//terminal bouton;GO:0001750//photoreceptor outer segment;GO:0017071//intracellular cyclic nucleotide activated cation channel complex;GO:0030660//Golgi-associated vesicle membrane;GO:0000139//Golgi membrane;GO:0005887//integral component of plasma membrane;GO:1902495//transmembrane transporter complex;GO:0005886//plasma membrane","GO:0015276//ligand-gated ion channel activity;GO:0030552//cAMP binding;GO:0005249//voltage-gated potassium channel activity;GO:0005223//intracellular cGMP activated cation channel activity;GO:0005222//intracellular cAMP activated cation channel activity;GO:0030553//cGMP binding","GO:0006810//transport;GO:0007608//sensory perception of smell;GO:0016056//rhodopsin mediated signaling pathway;GO:0035845//photoreceptor cell outer segment organization;GO:0050908//detection of light stimulus involved in visual perception;GO:0001895//retina homeostasis;GO:0007601//visual perception;GO:0006812//cation transport;GO:0051290//protein heterotetramerization;GO:0045494//photoreceptor cell maintenance;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0033365//protein localization to organelle;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0042391//regulation of membrane potential","K04952//cyclic nucleotide gated channel beta 1","NP_001129111.1//cyclic nucleotide-gated cation channel beta-1 isoform b [Homo sapiens];NP_001273059.1//cyclic nucleotide-gated cation channel beta-1 isoform c [Homo sapiens];NP_001288.3//cyclic nucleotide-gated cation channel beta-1 isoform a [Homo sapiens]","1//3;4"]
[780776,3439,1.91,2.63,0.461490161256553,0.0577112899593732,"*",0.0248996,"TVP23A","GO:0030173//integral component of Golgi membrane;GO:0016021//integral component of membrane","NA","GO:0009306//protein secretion;GO:0016192//vesicle-mediated transport","K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K01064//wingless-type MMTV integration site family, member 9","NP_001072980.1//Golgi apparatus membrane protein TVP23 homolog A isoform 1 [Homo sapiens];XP_011989660.2//PREDICTED: Golgi apparatus membrane protein TVP23 homolog A isoform X2 [Ovis aries musimon]","1//3;3//A2MP1"]
[103910,1005,217.13,298.98,0.461489908618367,{"v":4.263979755e-32,"d":"4.26E-32"},"*",{"v":1.06773E-33,"d":"1.07E-33"},"MYL12B","NA","NA","NA","K12757//myosin regulatory light chain 12","XP_004474453.1//PREDICTED: myosin regulatory light polypeptide 9 isoform X1 [Dasypus novemcinctus];ELK31627.1//Myosin regulatory light polypeptide 9 [Myotis davidii]","1//3;3//A2MP1"]
[8775,1865,110.1,151.52,0.460693767016654,{"v":6.98999910752688e-34,"d":"6.99E-34"},"*",{"v":1.62782e-35,"d":"1.63E-35"},"NAPA","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005622//intracellular;GO:0043209//myelin sheath;GO:0043195//terminal bouton;GO:0070044//synaptobrevin 2-SNAP-25-syntaxin-1a complex;GO:0000139//Golgi membrane;GO:0005774//vacuolar membrane;GO:0005829//cytosol;GO:0031201//SNARE complex;GO:0005886//plasma membrane","GO:0000149//SNARE binding;GO:0005483//soluble NSF attachment protein activity;GO:0019905//syntaxin binding;GO:0032403//protein complex binding","GO:0030182//neuron differentiation;GO:0035494//SNARE complex disassembly;GO:0048208//COPII vesicle coating;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0007420//brain development;GO:0045176//apical protein localization;GO:0006886//intracellular protein transport;GO:0061025//membrane fusion;GO:0032781//positive regulation of ATPase activity;GO:0035249//synaptic transmission, glutamatergic;GO:0010807//regulation of synaptic vesicle priming;GO:0006888//ER to Golgi vesicle-mediated transport","K15296//alpha-soluble NSF attachment protein","XP_012888195.1//PREDICTED: alpha-soluble NSF attachment protein [Dipodomys ordii]","3//A2MP1"]
[51267,2879,0.24,0.33,0.459431618637297,0.534814462728551,"*",0.380872,"CLEC1A","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005622//intracellular","GO:0030246//carbohydrate binding;GO:0004888//transmembrane signaling receptor activity","GO:0006952//defense response;GO:0007166//cell surface receptor signaling pathway","K10069//C-type lectin domain family 1 member A","NP_057595.2//C-type lectin domain family 1 member A isoform a [Homo sapiens];NP_001284677.1//C-type lectin domain family 1 member A isoform b [Homo sapiens];NP_001284678.1//C-type lectin domain family 1 member A isoform c [Homo sapiens];BAC11410.1//unnamed protein product [Homo sapiens];XP_018893321.1//PREDICTED: C-type lectin domain family 1 member A isoform X2 [Gorilla gorilla gorilla]","1//3;3//A2MP1"]
[79924,4045,0.88,1.21,0.459431618637297,0.219017366482505,"*",0.11912,"ADM2","NA","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K11447//histone demethylase [EC:1.14.11.-];K01064//wingless-type MMTV integration site family, member 9","CAG30365.1//dJ579N16.4 [Homo sapiens]","1//3"]
[23671,2816,0.08,0.11,0.459431618637297,0.811464862492111,"*",0.724446,"TMEFF2","GO:0016021//integral component of membrane;GO:0005576//extracellular region","NA","GO:0045720//negative regulation of integrin biosynthetic process;GO:0051497//negative regulation of stress fiber assembly;GO:0030336//negative regulation of cell migration;GO:0044319//wound healing, spreading of cells","K06254//agrin","XP_010387068.1//PREDICTED: tomoregulin-2 isoform X1 [Rhinopithecus roxellana];NP_001292074.1//tomoregulin-2 isoform 3 precursor [Homo sapiens]","1//3;3//A2MP1"]
[387032,5365,0.4,0.55,0.459431618637297,0.328987730133556,"*",0.1973844,"ZKSCAN4","NA","NA","NA","K09229//KRAB and SCAN domains-containing zinc finger protein","XP_007179164.1//PREDICTED: uncharacterized protein LOC102999167 [Balaenoptera acutorostrata scammoni];XP_012321245.1//zinc finger protein with KRAB and SCAN domains 4 isoform X1 [Aotus nancymaae]","1//3;4"]
[148979,2816,0.08,0.11,0.459431618637297,0.810839434136771,"*",0.724446,"GLIS1","GO:0005634//nucleus","GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding","GO:0006357//regulation of transcription from RNA polymerase II promoter","K09232//zinc finger protein GLIS1/3","XP_016855897.1//PREDICTED: zinc finger protein GLIS1 isoform X1 [Homo sapiens]","2//1"]
[9435,4154,0.08,0.11,0.459431618637297,0.665964246796827,"*",0.546646,"CHST2","GO:0005794//Golgi apparatus;GO:0031228//intrinsic component of Golgi membrane;GO:0016021//integral component of membrane;GO:0005802//trans-Golgi network;GO:0000139//Golgi membrane","GO:0008146//sulfotransferase activity;GO:0001517//N-acetylglucosamine 6-O-sulfotransferase activity","GO:0006790//sulfur compound metabolic process;GO:0018146//keratan sulfate biosynthetic process;GO:0006044//N-acetylglucosamine metabolic process;GO:0007275//multicellular organism development;GO:0005975//carbohydrate metabolic process;GO:0006954//inflammatory response","K04745//carbohydrate 6-sulfotransferase 2 [EC:2.8.2.-]","EDL77523.1//rCG25901 [Rattus norvegicus]",4]
[80031,5884,0.08,0.11,0.459431618637297,0.718621989731379,"*",0.60458,"SEMA6D","GO:0005887//integral component of plasma membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0030215//semaphorin receptor binding","GO:0014912//negative regulation of smooth muscle cell migration;GO:0030154//cell differentiation;GO:0021591//ventricular system development;GO:0014911//positive regulation of smooth muscle cell migration","K06842//semaphorin 6","NP_065909.1//semaphorin-6D isoform 1 precursor [Homo sapiens];XP_010597977.1//PREDICTED: LOW QUALITY PROTEIN: semaphorin-6D [Loxodonta africana];XP_014952552.1//PREDICTED: semaphorin-6D isoform X7 [Ovis aries];NP_705869.1//semaphorin-6D isoform 2 precursor [Homo sapiens];NP_705871.1//semaphorin-6D isoform 4 precursor [Homo sapiens];NP_705870.1//semaphorin-6D isoform 3 precursor [Homo sapiens];XP_005254742.1//PREDICTED: semaphorin-6D isoform X1 [Homo sapiens]","1//3;2//1"]
[55138,2516,0.32,0.44,0.459431618637297,0.658002113450203,"*",0.538092,"FAM90A1","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_018894904.1//PREDICTED: protein FAM90A1 isoform X2 [Gorilla gorilla gorilla]","1//3;3//A2MP1"]
[402415,2854,0.08,0.11,0.459431618637297,0.810498697576691,"*",0.724446,"XKRX","GO:0016021//integral component of membrane","NA","NA","K19522//membrane transport protein XK","XP_003940179.1//PREDICTED: XK-related protein 2 [Saimiri boliviensis boliviensis]","2//1"]
[794,1391,1.23,1.69,0.458364930942945,0.344742896665634,"*",0.20906,"CALB2","GO:0005634//nucleus;GO:0005921//gap junction;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0043195//terminal bouton;GO:0045202//synapse;GO:0043005//neuron projection","GO:0005509//calcium ion binding","GO:0051480//regulation of cytosolic calcium ion concentration","K14757//calbindin D28","NP_009019.1//calretinin isoform 22k [Homo sapiens];NP_001731.2//calretinin isoform 1 [Homo sapiens]","4;3//A2MP1"]
[64837,2801,45.52,62.54,0.458278661618458,{"v":7.74809408815427e-21,"d":"7.75E-21"},"*",{"v":3.52142e-22,"d":"3.52E-22"},"KLC2","GO:0016020//membrane;GO:0005874//microtubule;GO:0043234//protein complex;GO:0005829//cytosol;GO:0016938//kinesin I complex;GO:0005871//kinesin complex","GO:0003777//microtubule motor activity;GO:0019894//kinesin binding;GO:0045296//cadherin binding","GO:0007018//microtubule-based movement;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER","K10407//kinesin light chain","XP_011797838.1//PREDICTED: kinesin light chain 2 isoform X1 [Colobus angolensis palliatus];NP_073733.1//kinesin light chain 2 isoform 1 [Homo sapiens];NP_001128246.1//kinesin light chain 2 isoform 2 [Homo sapiens]","1//3;2//1"]
[64743,1945,31.74,43.6,0.458026006829107,{"v":8.23543959570436e-11,"d":"8.24E-11"},"*",{"v":8.1612e-12,"d":"8.16E-12"},"WDR13","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005815//microtubule organizing center;GO:0005886//plasma membrane","GO:1990841//promoter-specific chromatin binding","GO:1904691//negative regulation of type B pancreatic cell proliferation","K14963//COMPASS component SWD3","XP_012016279.1//PREDICTED: WD repeat-containing protein 13 isoform X2 [Ovis aries musimon];XP_021105636.1//WD repeat-containing protein 13 isoform X2 [Heterocephalus glaber];XP_016798097.1//PREDICTED: WD repeat-containing protein 13 isoform X2 [Pan troglodytes];XP_009195792.1//WD repeat-containing protein 13 isoform X1 [Papio anubis]","1//3;2//1;5"]
[151176,2911,2.41,3.31,0.457798070577256,0.0510993986162226,"*",0.0217302,"ERFE","GO:0005615//extracellular space;GO:0005623//cell;GO:0005576//extracellular region","GO:0042803//protein homodimerization activity;GO:0005179//hormone activity","GO:0019217//regulation of fatty acid metabolic process;GO:0006879//cellular iron ion homeostasis;GO:2000193//positive regulation of fatty acid transport","K21410//adipolin","NP_001278761.1//erythroferrone precursor [Homo sapiens]","1//3"]
[202915,6293,10.69,14.68,0.457590115122722,{"v":1.11554615253772e-11,"d":"1.12E-11"},"*",{"v":1.018196E-12,"d":"1.02E-12"},"TMEM184A","GO:0016021//integral component of membrane","NA","NA","K22020//mucin-19","XP_017824710.1//PREDICTED: transmembrane protein 184A [Callithrix jacchus]","1//3"]
[114757,2166,0.67,0.92,0.45747276559924,0.434429506792453,"*",0.288278,"CYGB","GO:0016607//nuclear speck;GO:0043025//neuronal cell body;GO:0043005//neuron projection","GO:0020037//heme binding;GO:0005506//iron ion binding;GO:0005344//oxygen carrier activity;GO:0019825//oxygen binding","NA","K21894//cytoglobin","EAW89405.1//cytoglobin, isoform CRA_a [Homo sapiens]",4]
[83658,716,216.24,296.86,0.457149295438882,{"v":1.64335596923077e-24,"d":"1.64E-24"},"*",{"v":5.88456e-26,"d":"5.88E-26"},"DYNLRB1","GO:0016020//membrane;GO:0005929//cilium;GO:0036157//outer dynein arm;GO:0005874//microtubule;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0097542//ciliary tip;GO:0005868//cytoplasmic dynein complex","GO:0045505//dynein intermediate chain binding;GO:0003774//motor activity;GO:0003777//microtubule motor activity","GO:0006810//transport;GO:0007018//microtubule-based movement;GO:0035735//intraciliary transport involved in cilium assembly;GO:0007632//visual behavior","K10419//dynein light chain roadblock-type","NP_001306086.1//dynein light chain roadblock-type 1 isoform d [Homo sapiens];EAW76268.1//hCG38498, isoform CRA_b [Homo sapiens];NP_001268658.1//dynein light chain roadblock-type 1 isoform c [Homo sapiens]","1//3;3//A2MP1;2//1"]
[79922,1851,13.17,18.08,0.457139332158673,{"v":9.51956152963671e-05,"d":"9.52E-05"},"*",{"v":2.18174e-05,"d":"2.18E-05"},"MRM1","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0003723//RNA binding;GO:0070039//rRNA (guanosine-2'-O-)-methyltransferase activity;GO:0008173//RNA methyltransferase activity","GO:0006396//RNA processing;GO:0000453//enzyme-directed rRNA 2'-O-methylation;GO:0000451//rRNA 2'-O-methylation","K15507//21S rRNA (GM2251-2'-O)-methyltransferase [EC:2.1.1.-]","XP_008009369.1//PREDICTED: rRNA methyltransferase 1, mitochondrial [Chlorocebus sabaeus]",4]
[4061,1192,180.28,247.49,0.457130878139993,{"v":2.99313372054795e-34,"d":"2.99E-34"},"*",{"v":6.8392e-36,"d":"6.84E-36"},"LY6E","GO:0005887//integral component of plasma membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0031225//anchored component of membrane","NA","GO:0006501//C-terminal protein lipidation;GO:0007166//cell surface receptor signaling pathway","K06846//lymphocyte antigen 6 complex locus protein D/E/G6/H","NP_002337.1//lymphocyte antigen 6E precursor [Homo sapiens]","1//3;2//1"]
[29937,995,51.5,70.69,0.456933709601638,{"v":9.16383576808722e-09,"d":"9.16E-09"},"*",{"v":1.15767E-9,"d":"1.16E-09"},"NENF","GO:0016020//membrane;GO:0012505//endomembrane system;GO:0005615//extracellular space","GO:0046872//metal ion binding;GO:0008083//growth factor activity","GO:0043410//positive regulation of MAPK cascade;GO:0032099//negative regulation of appetite","K17278//membrane-associated progesterone receptor component","NP_037481.1//neudesin precursor [Homo sapiens]",4]
[9136,1590,32.58,44.72,0.456933584317672,{"v":5.37410883034341e-09,"d":"5.37E-09"},"*",{"v":6.56372E-10,"d":"6.56E-10"},"RRP9","GO:0005654//nucleoplasm;GO:0032040//small-subunit processome;GO:0005730//nucleolus;GO:0031428//box C/D snoRNP complex","GO:0030515//snoRNA binding;GO:0034511//U3 snoRNA binding;GO:0003723//RNA binding","GO:0006364//rRNA processing","K14793//ribosomal RNA-processing protein 9","NP_004695.1//U3 small nucleolar RNA-interacting protein 2 [Homo sapiens]",4]
[2015,2630,3.25,4.46,0.456603992004488,0.0294265678841871,"*",0.01157978,"ADGRE1","GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016021//integral component of membrane","GO:0005509//calcium ion binding;GO:0004930//G-protein coupled receptor activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0007155//cell adhesion;GO:0007166//cell surface receptor signaling pathway;GO:0002250//adaptive immune response","K04591//egf-like module containing, mucin-like, hormone receptor-like 1","NP_001243182.1//adhesion G protein-coupled receptor E1 isoform 3 precursor [Homo sapiens];NP_001965.3//adhesion G protein-coupled receptor E1 isoform 1 precursor [Homo sapiens];NP_001243184.1//adhesion G protein-coupled receptor E1 isoform 5 precursor [Homo sapiens];NP_001243181.1//adhesion G protein-coupled receptor E1 isoform 2 precursor [Homo sapiens];NP_001243183.1//adhesion G protein-coupled receptor E1 isoform 4 precursor [Homo sapiens]","4;1//3"]
[7311,2840,95.63,131.17,0.455902616829982,{"v":4.84867696444444e-43,"d":"4.85E-43"},"*",{"v":8.19546e-45,"d":"8.20E-45"},"UBA52","NA","NA","NA","K08770//ubiquitin C;K02927//large subunit ribosomal protein L40e","XP_016882687.1//PREDICTED: ubiquitin-60S ribosomal protein L40 isoform X1 [Homo sapiens];NP_001307950.1//ubiquitin-60S ribosomal protein L40 isoform 2 [Homo sapiens];XP_003277840.2//PREDICTED: ubiquitin-60S ribosomal protein L40-like isoform X1 [Nomascus leucogenys];EPY79925.1//ubiquitin A-52 residue ribosomal protein fusion product 1-like protein [Camelus ferus];XP_004060373.2//PREDICTED: ubiquitin-60S ribosomal protein L40 isoform X3 [Gorilla gorilla gorilla]","4;1//3;2//1"]
[3400,3891,2.96,4.06,0.455882551556226,0.00981265799237611,"*",3.38412E-3,"ID4","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0001085//RNA polymerase II transcription factor binding;GO:0046983//protein dimerization activity","GO:0048712//negative regulation of astrocyte differentiation;GO:0021766//hippocampus development;GO:0022010//central nervous system myelination;GO:0061682//seminal vesicle morphogenesis;GO:0060740//prostate gland epithelium morphogenesis;GO:0007405//neuroblast proliferation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007623//circadian rhythm;GO:0045892//negative regulation of transcription, DNA-templated;GO:0021895//cerebral cortex neuron differentiation;GO:0006351//transcription, DNA-templated;GO:0060741//prostate gland stromal morphogenesis;GO:0045599//negative regulation of fat cell differentiation;GO:0048715//negative regulation of oligodendrocyte differentiation;GO:0045669//positive regulation of osteoblast differentiation;GO:0045665//negative regulation of neuron differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045444//fat cell differentiation;GO:0000082//G1/S transition of mitotic cell cycle;GO:0034613//cellular protein localization;GO:0008284//positive regulation of cell proliferation","K17695//DNA-binding protein inhibitor ID4","NP_001537.1//DNA-binding protein inhibitor ID-4 [Homo sapiens]","3//A2MP1"]
[1535,778,247.53,339.42,0.45546819009452,{"v":6.2721492546697e-30,"d":"6.27E-30"},"*",{"v":1.723722e-31,"d":"1.72E-31"},"CYBA","GO:0016020//membrane;GO:0030425//dendrite;GO:0097038//perinuclear endoplasmic reticulum;GO:0016324//apical plasma membrane;GO:0043025//neuronal cell body;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0070821//tertiary granule membrane;GO:0005886//plasma membrane;GO:0005634//nucleus;GO:0005925//focal adhesion;GO:0030670//phagocytic vesicle membrane;GO:0005768//endosome;GO:0030141//secretory granule;GO:0001725//stress fiber;GO:0005794//Golgi apparatus;GO:0043020//NADPH oxidase complex;GO:0035579//specific granule membrane;GO:0005789//endoplasmic reticulum membrane","GO:0009055//electron transfer activity;GO:0046872//metal ion binding;GO:0020037//heme binding;GO:0046982//protein heterodimerization activity;GO:0017124//SH3 domain binding;GO:0016175//superoxide-generating NADPH oxidase activity","GO:0006801//superoxide metabolic process;GO:0032930//positive regulation of superoxide anion generation;GO:0071260//cellular response to mechanical stimulus;GO:1903428//positive regulation of reactive oxygen species biosynthetic process;GO:1904385//cellular response to angiotensin;GO:0017004//cytochrome complex assembly;GO:1900426//positive regulation of defense response to bacterium;GO:0071356//cellular response to tumor necrosis factor;GO:1904044//response to aldosterone;GO:0045454//cell redox homeostasis;GO:0032760//positive regulation of tumor necrosis factor production;GO:0070555//response to interleukin-1;GO:1904845//cellular response to L-glutamine;GO:0045087//innate immune response;GO:0042493//response to drug;GO:0001666//response to hypoxia;GO:0071333//cellular response to glucose stimulus;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0034599//cellular response to oxidative stress;GO:0032755//positive regulation of interleukin-6 production;GO:0070257//positive regulation of mucus secretion;GO:0051279//regulation of release of sequestered calcium ion into cytosol;GO:0030307//positive regulation of cell growth;GO:0033864//positive regulation of NAD(P)H oxidase activity;GO:0055114//oxidation-reduction process;GO:0050766//positive regulation of phagocytosis;GO:0071407//cellular response to organic cyclic compound;GO:0043312//neutrophil degranulation;GO:0042554//superoxide anion generation;GO:0001938//positive regulation of endothelial cell proliferation;GO:0034137//positive regulation of toll-like receptor 2 signaling pathway;GO:0014823//response to activity;GO:0071480//cellular response to gamma radiation;GO:0006954//inflammatory response;GO:0045730//respiratory burst;GO:0014895//smooth muscle hypertrophy;GO:0031667//response to nutrient levels;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0050665//hydrogen peroxide biosynthetic process;GO:0003106//negative regulation of glomerular filtration by angiotensin","K08009//cytochrome b-245, alpha polypeptide","NP_000092.2//cytochrome b-245 light chain [Homo sapiens]","3//A2MP1"]
[11066,998,8.69,11.91,0.454745331049714,0.020667633068616,"*",0.00778756,"SNRNP35","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005689//U12-type spliceosomal complex;GO:0071011//precatalytic spliceosome;GO:0000243//commitment complex","GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0017069//snRNA binding","GO:0000398//mRNA splicing, via spliceosome;GO:0008380//RNA splicing","K13155//U11/U12 small nuclear ribonucleoprotein 35 kDa protein","XP_011536082.1//PREDICTED: U11/U12 small nuclear ribonucleoprotein 35 kDa protein isoform X1 [Homo sapiens];NP_851030.1//U11/U12 small nuclear ribonucleoprotein 35 kDa protein isoform b [Homo sapiens]","3//A2MP1"]
[2766,1515,0.27,0.37,0.454565863465481,0.695583069536424,"*",0.578622,"GMPR","GO:1902560//GMP reductase complex;GO:0005829//cytosol","GO:0046872//metal ion binding;GO:0003920//GMP reductase activity","GO:0009409//response to cold;GO:0006144//purine nucleobase metabolic process;GO:0043101//purine-containing compound salvage;GO:0006163//purine nucleotide metabolic process;GO:0009117//nucleotide metabolic process","K00364//GMP reductase [EC:1.7.1.7]","NP_006868.3//GMP reductase 1 [Homo sapiens]","3//A2MP1"]
[9567,5074,5.27,7.22,0.454195875249957,{"v":3.97212737962963e-05,"d":"3.97E-05"},"*",{"v":8.59376e-06,"d":"8.59E-06"},"GTPBP1","GO:0016020//membrane;GO:0005829//cytosol;GO:0000177//cytoplasmic exosome (RNase complex)","GO:0003723//RNA binding;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0007165//signal transduction;GO:0061014//positive regulation of mRNA catabolic process;GO:0006955//immune response;GO:0046039//GTP metabolic process","K01064//wingless-type MMTV integration site family, member 9","NP_004277.2//GTP-binding protein 1 [Homo sapiens]",4]
[6209,550,537.76,736.46,0.453644721265268,{"v":3.24821608787879e-44,"d":"3.25E-44"},"*",{"v":5.36828e-46,"d":"5.37E-46"},"RPS15","GO:0022627//cytosolic small ribosomal subunit;GO:0015935//small ribosomal subunit","GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome","GO:0000028//ribosomal small subunit assembly;GO:0006412//translation","K02958//small subunit ribosomal protein S15e","XP_001373175.3//PREDICTED: 40S ribosomal protein S15 [Monodelphis domestica];NP_001295155.1//40S ribosomal protein S15 isoform 1 [Homo sapiens]","1//3;4"]
[79090,752,18.11,24.79,0.452971725136554,0.00940712471918308,"*",0.00322954,"TRAPPC6A","GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0030008//TRAPP complex;GO:0005802//trans-Golgi network;GO:0005801//cis-Golgi network;GO:0000139//Golgi membrane","GO:0017112//Rab guanyl-nucleotide exchange factor activity","GO:0048208//COPII vesicle coating;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0061024//membrane organization;GO:1903232//melanosome assembly","K20304//trafficking protein particle complex subunit 6","NP_077013.1//trafficking protein particle complex subunit 6A isoform 1 [Homo sapiens];NP_001257820.1//trafficking protein particle complex subunit 6A isoform 2 [Homo sapiens];XP_012352306.1//PREDICTED: trafficking protein particle complex subunit 6A isoform X4 [Nomascus leucogenys];XP_012352305.1//PREDICTED: trafficking protein particle complex subunit 6A isoform X3 [Nomascus leucogenys]","1//3;2//1"]
[114897,2737,16.3,22.31,0.452818549125701,{"v":4.85595176523702e-08,"d":"4.86E-08"},"*",{"v":6.7334e-09,"d":"6.73E-09"},"C1QTNF1","GO:0005634//nucleus;GO:0005615//extracellular space;GO:0005887//integral component of plasma membrane;GO:0005829//cytosol;GO:0005576//extracellular region;GO:0005581//collagen trimer","GO:0005518//collagen binding","GO:0051897//positive regulation of protein kinase B signaling;GO:0051260//protein homooligomerization;GO:0010628//positive regulation of gene expression;GO:2000860//positive regulation of aldosterone secretion;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0043410//positive regulation of MAPK cascade;GO:0070208//protein heterotrimerization;GO:0010906//regulation of glucose metabolic process;GO:0090331//negative regulation of platelet aggregation","K19470//complement C1q tumor necrosis factor-related protein 6","XP_008046495.1//complement C1q tumor necrosis factor-related protein 1 [Carlito syrichta];XP_005407403.1//PREDICTED: complement C1q tumor necrosis factor-related protein 1 isoform X1 [Chinchilla lanigera]","4;3//A2MP1;2//1"]
[6610,1697,9.55,13.07,0.452686502872322,0.00212945398826979,"*",0.00063641,"SMPD2","GO:0005901//caveola;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005622//intracellular;GO:0005886//plasma membrane","GO:0046872//metal ion binding;GO:0004767//sphingomyelin phosphodiesterase activity","GO:2000304//positive regulation of ceramide biosynthetic process;GO:0009612//response to mechanical stimulus;GO:0035556//intracellular signal transduction;GO:0006684//sphingomyelin metabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0046513//ceramide biosynthetic process","K12351//sphingomyelin phosphodiesterase 2 [EC:3.1.4.12]","NP_003071.2//sphingomyelin phosphodiesterase 2 [Homo sapiens]","2//1"]
[79792,1772,10.69,14.63,0.452667916417996,0.00116868732612056,"*",3.3135E-4,"GSDMD","GO:1904724//tertiary granule lumen;GO:0005654//nucleoplasm;GO:0005615//extracellular space;GO:0035580//specific granule lumen;GO:0072559//NLRP3 inflammasome complex;GO:0005829//cytosol;GO:0005576//extracellular region;GO:1904813//ficolin-1-rich granule lumen;GO:0005886//plasma membrane","GO:1901612//cardiolipin binding;GO:0070273//phosphatidylinositol-4-phosphate binding;GO:0070300//phosphatidic acid binding;GO:0001786//phosphatidylserine binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding","GO:0046931//pore complex assembly;GO:0070269//pyroptosis;GO:0050718//positive regulation of interleukin-1 beta secretion;GO:0050829//defense response to Gram-negative bacterium;GO:0019835//cytolysis;GO:0051260//protein homooligomerization;GO:0006954//inflammatory response;GO:0035915//pore formation in membrane of other organism;GO:0043312//neutrophil degranulation;GO:0050830//defense response to Gram-positive bacterium;GO:0045087//innate immune response;GO:0031668//cellular response to extracellular stimulus","K20917//gasdermin-D","EAW82246.1//gasdermin domain containing 1, isoform CRA_d [Homo sapiens]","6;1//3"]
[284739,2669,0.38,0.52,0.452512204697507,0.51407080060992,"*",0.358794,"C20orf204","NA","NA","NA","K16628//collagen, type VII, alpha;K00894//ethanolamine kinase [EC:2.7.1.82];K06236//collagen, type I, alpha;K03145//transcription elongation factor S-II","NP_001335019.1//putative uncharacterized protein C20orf204 precursor [Homo sapiens]","1//3"]
[26233,1797,15.28,20.9,0.451858398932496,{"v":3.61944371995333e-05,"d":"3.62E-05"},"*",{"v":7.76728e-06,"d":"7.77E-06"},"FBXL6","NA","GO:0004842//ubiquitin-protein transferase activity","GO:0006508//proteolysis","K10272//F-box and leucine-rich repeat protein 6","NP_078831.4//F-box/LRR-repeat protein 6 isoform 2 [Homo sapiens];NP_036294.2//F-box/LRR-repeat protein 6 isoform 1 [Homo sapiens]","3//A2MP1;5"]
[10557,1379,16.22,22.18,0.451485545944437,0.0186320327444052,"*",0.0069319,"RPP38","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005655//nucleolar ribonuclease P complex;GO:0001650//fibrillar center","GO:0004526//ribonuclease P activity","GO:0001682//tRNA 5'-leader removal;GO:0006364//rRNA processing","K14523//ribonucleases P/MRP protein subunit RPP38 [EC:3.1.26.5]","XP_016801925.1//PREDICTED: ribonuclease P protein subunit p38 isoform X1 [Pan troglodytes];NP_892117.1//ribonuclease P protein subunit p38 [Homo sapiens]","4;1//3;2//1"]
[6710,9801,0.49,0.67,0.451379346342564,0.161139281920078,"*",0.082799,"SPTB","NA","NA","NA","K06115//spectrin beta","XP_012579934.1//PREDICTED: spectrin beta chain, erythrocytic isoform X1 [Condylura cristata];XP_004681841.1//PREDICTED: spectrin beta chain, erythrocytic isoform X2 [Condylura cristata]","1//3;3//A2MP1"]
[83442,1131,132.17,180.71,0.45128159273138,{"v":2.0549170371567e-23,"d":"2.05E-23"},"*",{"v":7.9629e-25,"d":"7.96E-25"},"SH3BGRL3","NA","NA","NA","K16342//cytosolic phospholipase A2 [EC:3.1.1.4];K13912//deleted in malignant brain tumors 1 protein","EAX07831.1//SH3 domain binding glutamic acid-rich protein like 3, isoform CRA_a, partial [Homo sapiens]","3//A2MP1"]
[11119,3581,2.18,2.98,0.450984195685235,0.033732440655533,"*",0.01352972,"BTN3A1","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","NA","GO:0050663//cytokine secretion;GO:0050798//activated T cell proliferation;GO:0072643//interferon-gamma secretion;GO:0050852//T cell receptor signaling pathway;GO:0002250//adaptive immune response","K06712//butyrophilin","NP_001138480.1//butyrophilin subfamily 3 member A1 isoform c precursor [Homo sapiens];NP_001138481.1//butyrophilin subfamily 3 member A1 isoform d precursor [Homo sapiens];NP_919423.1//butyrophilin subfamily 3 member A1 isoform b precursor [Homo sapiens];NP_008979.3//butyrophilin subfamily 3 member A1 isoform a precursor [Homo sapiens]","1//3;2//1;5"]
[84300,1355,13.25,18.11,0.450794186612244,0.0012646445476086,"*",0.000360852,"UQCC2","GO:0005759//mitochondrial matrix;GO:0042645//mitochondrial nucleoid;GO:0016604//nuclear body;GO:0005758//mitochondrial intermembrane space;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","NA","GO:1903364//positive regulation of cellular protein catabolic process;GO:0034551//mitochondrial respiratory chain complex III assembly;GO:2001014//regulation of skeletal muscle cell differentiation;GO:0070131//positive regulation of mitochondrial translation;GO:0002082//regulation of oxidative phosphorylation;GO:0050796//regulation of insulin secretion","K17682//mitochondrial nucleoid factor 1","XP_003923203.1//PREDICTED: ubiquinol-cytochrome-c reductase complex assembly factor 2 [Saimiri boliviensis boliviensis]","3//A2MP1"]
[84266,1331,13.99,19.12,0.450686560815995,0.000996329156906571,"*",0.000279052,"ALKBH7","GO:0005759//mitochondrial matrix","GO:0046872//metal ion binding;GO:0051213//dioxygenase activity","GO:1902445//regulation of mitochondrial membrane permeability involved in programmed necrotic cell death;GO:0006631//fatty acid metabolic process;GO:0010883//regulation of lipid storage;GO:0006974//cellular response to DNA damage stimulus","K10769//alkylated DNA repair protein alkB homolog 7 [EC:1.14.11.-]","XP_017383808.1//PREDICTED: alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial [Cebus capucinus imitator]","3//A2MP1"]
[643988,2104,11.24,15.36,0.45053618050023,0.000159298618647166,"*",{"v":3.81842e-05,"d":"3.82E-05"},"FNDC10","GO:0016021//integral component of membrane","NA","NA","K16628//collagen, type VII, alpha;K11094//U2 small nuclear ribonucleoprotein B'';K15544//RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]","NP_001229588.1//fibronectin type III domain-containing protein 10 precursor [Homo sapiens]","1//3"]
[51310,2113,5.38,7.35,0.450138077167103,0.00422918093663912,"*",1.34548E-3,"SLC22A17","GO:0005774//vacuolar membrane;GO:0005887//integral component of plasma membrane;GO:0031301//integral component of organelle membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004888//transmembrane signaling receptor activity;GO:0008514//organic anion transmembrane transporter activity;GO:0022857//transmembrane transporter activity","GO:0006879//cellular iron ion homeostasis;GO:0015891//siderophore transport","K08213//MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 17","XP_014711772.1//PREDICTED: solute carrier family 22 member 17 isoform X1 [Equus asinus];XP_013012739.1//PREDICTED: solute carrier family 22 member 17 [Cavia porcellus];XP_003808140.1//PREDICTED: solute carrier family 22 member 17 isoform X2 [Pan paniscus]","4;1//3;3//A2MP1"]
[27106,2540,12,16.39,0.449781448603578,{"v":1.53668678947368e-05,"d":"1.54E-05"},"*",{"v":3.07068E-6,"d":"3.07E-06"},"ARRDC2","GO:0031410//cytoplasmic vesicle;GO:0005886//plasma membrane","NA","NA","K20910//thioredoxin-interacting protein","NP_056498.1//arrestin domain-containing protein 2 isoform 1 [Homo sapiens];XP_017356769.1//PREDICTED: arrestin domain-containing protein 2 isoform X1 [Cebus capucinus imitator];NP_001273755.1//arrestin domain-containing protein 2 isoform 3 [Homo sapiens]","1//3;2//1"]
[10084,938,57.99,79.19,0.44951412206895,{"v":4.84621517525773e-07,"d":"4.85E-07"},"*",{"v":7.65128e-08,"d":"7.65E-08"},"PQBP1","GO:0010494//cytoplasmic stress granule;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0071598//neuronal ribonucleoprotein granule","GO:0003677//DNA binding;GO:0003713//transcription coactivator activity;GO:0043021//ribonucleoprotein complex binding;GO:0003690//double-stranded DNA binding","GO:0043484//regulation of RNA splicing;GO:0032481//positive regulation of type I interferon production;GO:0000398//mRNA splicing, via spliceosome;GO:0006355//regulation of transcription, DNA-templated;GO:0002218//activation of innate immune response;GO:0051607//defense response to virus;GO:0071360//cellular response to exogenous dsRNA;GO:0006351//transcription, DNA-templated;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0031175//neuron projection development;GO:0048814//regulation of dendrite morphogenesis;GO:0045087//innate immune response;GO:0002230//positive regulation of defense response to virus by host","K12865//polyglutamine-binding protein 1","XP_012354320.1//PREDICTED: polyglutamine-binding protein 1 isoform X1 [Nomascus leucogenys];XP_017379387.1//PREDICTED: polyglutamine-binding protein 1 isoform X3 [Cebus capucinus imitator];XP_008957541.1//PREDICTED: polyglutamine-binding protein 1 isoform X1 [Pan paniscus];XP_008957542.1//PREDICTED: polyglutamine-binding protein 1 isoform X2 [Pan paniscus];EAW50738.1//polyglutamine binding protein 1, isoform CRA_d [Homo sapiens];NP_001161464.1//polyglutamine-binding protein 1 isoform 6 [Homo sapiens]","1//3;2//1"]
[8000,1038,2.38,3.25,0.449478144607873,0.32083571458508,"*",0.19169,"PSCA","GO:0070062//extracellular exosome;GO:0005886//plasma membrane","GO:0033130//acetylcholine receptor binding","GO:0099601//regulation of neurotransmitter receptor activity;GO:0070373//negative regulation of ERK1 and ERK2 cascade","K06846//lymphocyte antigen 6 complex locus protein D/E/G6/H","XP_003819533.1//PREDICTED: prostate stem cell antigen [Pan paniscus]",4]
[435,1969,7.67,10.47,0.448962959427875,0.00414069889826498,"*",1.314738E-3,"ASL","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0004056//argininosuccinate lyase activity;GO:0042802//identical protein binding","GO:0007626//locomotory behavior;GO:0009791//post-embryonic development;GO:0042450//arginine biosynthetic process via ornithine;GO:0000050//urea cycle;GO:0019676//ammonia assimilation cycle","K01755//argininosuccinate lyase [EC:4.3.2.1]","NP_001020117.1//argininosuccinate lyase isoform 3 [Homo sapiens];NP_000039.2//argininosuccinate lyase isoform 1 [Homo sapiens];NP_001020115.1//argininosuccinate lyase isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[84798,1518,150.19,205.01,0.448905525328159,{"v":1.67977066518106E-34,"d":"1.68E-34"},"*",{"v":3.77512e-36,"d":"3.78E-36"},"C19orf48","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein;K12642//plakophilin 2","XP_004089434.1//PREDICTED: uncharacterized protein C19orf48 homolog [Nomascus leucogenys]","1//3;2//1"]
[84987,757,27.78,37.91,0.448531857189251,4.80977940797326E-4,"*",1.26131E-4,"COX14","GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0031966//mitochondrial membrane","NA","GO:0033617//mitochondrial respiratory chain complex IV assembly","K18181//cytochrome c oxidase assembly factor 14","EHH20721.1//hypothetical protein EGK_03635 [Macaca mulatta]","1//3;3//A2MP1"]
[22839,3781,24.64,33.62,0.448317468541266,{"v":3.93608465046102e-14,"d":"3.94E-14"},"*",{"v":2.93962e-15,"d":"2.94E-15"},"DLGAP4","GO:0045202//synapse;GO:0005886//plasma membrane","GO:0019904//protein domain specific binding","GO:0023052//signaling;GO:0006461//protein complex assembly","K15008//discs, large-associated protein 1","XP_021776782.1//disks large-associated protein 4 isoform X7 [Papio anubis];NP_892118.1//disks large-associated protein 4 isoform b [Homo sapiens];NP_055717.2//disks large-associated protein 4 isoform a [Homo sapiens]","3//A2MP1;5"]
[59286,476,89.81,122.53,0.448187021445484,{"v":2.94877912372941e-06,"d":"2.95E-06"},"*",{"v":5.2666e-07,"d":"5.27E-07"},"UBL5","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0031386//protein tag","GO:0000398//mRNA splicing, via spliceosome;GO:0006464//cellular protein modification process;GO:1903955//positive regulation of protein targeting to mitochondrion","K13113//ubiquitin-like protein 5","XP_007104382.1//PREDICTED: ubiquitin-like protein 5 isoform X1 [Physeter catodon];XP_004464750.1//PREDICTED: ubiquitin-like protein 5 [Dasypus novemcinctus]","3//A2MP1;2//1"]
[54556,1921,1.62,2.21,0.448052556506807,0.352110747765334,"*",0.214542,"ING3","GO:0000812//Swr1 complex;GO:0035267//NuA4 histone acetyltransferase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0032777//Piccolo NuA4 histone acetyltransferase complex","GO:0046872//metal ion binding;GO:0004402//histone acetyltransferase activity;GO:0035064//methylated histone binding","GO:0043065//positive regulation of apoptotic process;GO:0043967//histone H4 acetylation;GO:0016569//covalent chromatin modification;GO:0006355//regulation of transcription, DNA-templated;GO:0040008//regulation of growth;GO:0043968//histone H2A acetylation;GO:0006351//transcription, DNA-templated","K11319//inhibitor of growth protein 3","AAF28979.1//HSPC301, partial [Homo sapiens];NP_061944.2//inhibitor of growth protein 3 isoform 1 [Homo sapiens]","1//3;2//1"]
[2877,1105,147.59,201.32,0.447895528426845,{"v":4.72224827099099e-25,"d":"4.72E-25"},"*",{"v":1.640696e-26,"d":"1.64E-26"},"GPX2","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0009055//electron transfer activity;GO:0004602//glutathione peroxidase activity","GO:0034599//cellular response to oxidative stress","K00432//glutathione peroxidase [EC:1.11.1.9]","NP_002074.2//glutathione peroxidase 2 [Homo sapiens]","3//A2MP1"]
[2274,1568,17.64,24.06,0.447786081618556,{"v":2.36297374848851e-05,"d":"2.36E-05"},"*",{"v":4.8934e-06,"d":"4.89E-06"},"FHL2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0030018//Z disc;GO:0031430//M band;GO:0005925//focal adhesion","GO:0046872//metal ion binding;GO:0003713//transcription coactivator activity;GO:0050681//androgen receptor binding;GO:0042802//identical protein binding;GO:0008134//transcription factor binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0055015//ventricular cardiac muscle cell development;GO:0001649//osteoblast differentiation;GO:0055014//atrial cardiac muscle cell development;GO:0006351//transcription, DNA-templated;GO:0043066//negative regulation of apoptotic process;GO:0030521//androgen receptor signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0009725//response to hormone;GO:0060347//heart trabecula formation;GO:0019216//regulation of lipid metabolic process","K14380//four and a half LIM domains protein 2","XP_003922830.1//PREDICTED: four and a half LIM domains protein 2 isoform X1 [Saimiri boliviensis boliviensis];XP_012351184.1//PREDICTED: four and a half LIM domains protein 2 isoform X1 [Nomascus leucogenys];ABB73038.1//FHL2 isoform 5 [Homo sapiens];XP_004031594.2//PREDICTED: LOW QUALITY PROTEIN: four and a half LIM domains protein 2 [Gorilla gorilla gorilla];XP_003775909.1//PREDICTED: four and a half LIM domains protein 2 isoform X1 [Pongo abelii];XP_017730526.1//PREDICTED: four and a half LIM domains protein 2 isoform X2 [Rhinopithecus bieti];XP_002811776.1//PREDICTED: four and a half LIM domains protein 2 isoform X3 [Pongo abelii]","1//3;3//A2MP1;2//1"]
[7108,1613,8.66,11.81,0.447570034670432,5.27319625945946E-3,"*",1.709976E-3,"TM7SF2","GO:0043231//intracellular membrane-bounded organelle;GO:0005783//endoplasmic reticulum;GO:0005887//integral component of plasma membrane;GO:0031090//organelle membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0043235//receptor complex","GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors;GO:0050661//NADP binding;GO:0016628//oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;GO:0050613//delta14-sterol reductase activity","GO:0016126//sterol biosynthetic process;GO:0006695//cholesterol biosynthetic process;GO:0045540//regulation of cholesterol biosynthetic process","K00222//Delta14-sterol reductase [EC:1.3.1.70]","NP_001264162.1//delta(14)-sterol reductase isoform 2 [Homo sapiens];NP_003264.2//delta(14)-sterol reductase isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[5129,3134,0.99,1.35,0.447458976971221,0.301354636761722,"*",0.176636,"CDK18","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity","GO:0006468//protein phosphorylation","K15596//cyclin-dependent kinase 18 [EC:2.7.11.22]","XP_016856912.1//PREDICTED: cyclin-dependent kinase 18 isoform X1 [Homo sapiens];XP_011507904.1//PREDICTED: cyclin-dependent kinase 18 isoform X2 [Homo sapiens]","3//A2MP1;2//1"]
[1636,4687,0.11,0.15,0.447458976971221,0.868838438209118,"*",0.800578,"ACE","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0009897//external side of plasma membrane;GO:0005764//lysosome;GO:0005768//endosome;GO:0005576//extracellular region;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004175//endopeptidase activity;GO:0004180//carboxypeptidase activity;GO:0031711//bradykinin receptor binding;GO:0008241//peptidyl-dipeptidase activity;GO:0031434//mitogen-activated protein kinase kinase binding;GO:0008238//exopeptidase activity;GO:0008240//tripeptidyl-peptidase activity;GO:0003779//actin binding;GO:0031404//chloride ion binding;GO:0070573//metallodipeptidase activity;GO:0046872//metal ion binding;GO:0051019//mitogen-activated protein kinase binding;GO:0008237//metallopeptidase activity;GO:0008144//drug binding;GO:0008270//zinc ion binding","GO:0008217//regulation of blood pressure;GO:2000170//positive regulation of peptidyl-cysteine S-nitrosylation;GO:0010608//posttranscriptional regulation of gene expression;GO:0032092//positive regulation of protein binding;GO:0050435//amyloid-beta metabolic process;GO:0050482//arachidonic acid secretion;GO:0071838//cell proliferation in bone marrow;GO:0032091//negative regulation of protein binding;GO:0060177//regulation of angiotensin metabolic process;GO:0002005//angiotensin catabolic process in blood;GO:0097746//regulation of blood vessel diameter;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0043171//peptide catabolic process;GO:0001974//blood vessel remodeling;GO:0006508//proteolysis;GO:0060047//heart contraction;GO:1903597//negative regulation of gap junction assembly;GO:0032943//mononuclear cell proliferation;GO:1900086//positive regulation of peptidyl-tyrosine autophosphorylation;GO:0002019//regulation of renal output by angiotensin;GO:0001822//kidney development;GO:0019229//regulation of vasoconstriction;GO:0010629//negative regulation of gene expression;GO:0007283//spermatogenesis;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0002446//neutrophil mediated immunity;GO:0002003//angiotensin maturation;GO:0042447//hormone catabolic process;GO:0060218//hematopoietic stem cell differentiation;GO:0003084//positive regulation of systemic arterial blood pressure;GO:1902033//regulation of hematopoietic stem cell proliferation;GO:0003081//regulation of systemic arterial blood pressure by renin-angiotensin;GO:0014910//regulation of smooth muscle cell migration","K01283//peptidyl-dipeptidase A [EC:3.4.15.1]","XP_011803323.1//PREDICTED: angiotensin-converting enzyme isoform X3 [Colobus angolensis palliatus];NP_000780.1//angiotensin-converting enzyme isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1;2//1"]
[284307,4294,0.11,0.15,0.447458976971221,0.578735426951817,"*",0.421824,"ZIK1","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","XP_012606836.1//zinc finger protein interacting with ribonucleoprotein K isoform X1 [Microcebus murinus]","1//3;3//A2MP1"]
[2700,5219,0.11,0.15,0.447458976971221,0.634369083810948,"*",0.4781,"GJA3","GO:0005922//connexin complex;GO:0016021//integral component of membrane","GO:0005243//gap junction channel activity","GO:0006810//transport;GO:0007154//cell communication;GO:0007267//cell-cell signaling;GO:0007601//visual perception","K07612//gap junction alpha-3 protein","NP_068773.2//gap junction alpha-3 protein [Homo sapiens]","3//A2MP1"]
[4237,1105,0.22,0.3,0.447458976971221,0.810328436664099,"*",0.724446,"MFAP2","GO:0001527//microfibril;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix","NA","GO:0048050//post-embryonic eye morphogenesis;GO:0030198//extracellular matrix organization;GO:0048048//embryonic eye morphogenesis","K13526//cation-transporting P-type ATPase 13A2 [EC:3.6.3.-]","XP_007978520.1//PREDICTED: microfibrillar-associated protein 2 isoform X2 [Chlorocebus sabaeus];XP_007978519.1//PREDICTED: microfibrillar-associated protein 2 isoform X1 [Chlorocebus sabaeus]","1//3;3//A2MP1;2//1"]
[65991,2981,18.16,24.76,0.44724711192335,{"v":4.37545314759192e-09,"d":"4.38E-09"},"*",{"v":5.28922e-10,"d":"5.29E-10"},"FUNDC2","GO:0005634//nucleus;GO:0031307//integral component of mitochondrial outer membrane;GO:0005739//mitochondrion","NA","GO:0000422//autophagy of mitochondrion","K17986//FUN14 domain-containing protein 1;K16524//A-kinase anchor protein 7","XP_017371700.1//PREDICTED: FUN14 domain-containing protein 2 [Cebus capucinus imitator]","3//A2MP1"]
[7494,1810,21.61,29.46,0.447058358176342,{"v":8.6635086402439e-07,"d":"8.66E-07"},"*",{"v":1.423128E-7,"d":"1.42E-07"},"XBP1","GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005789//endoplasmic reticulum membrane;GO:0005737//cytoplasm","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity;GO:0001158//enhancer sequence-specific DNA binding;GO:0031490//chromatin DNA binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0001047//core promoter binding","GO:0030335//positive regulation of cell migration;GO:1903489//positive regulation of lactation;GO:1900100//positive regulation of plasma cell differentiation;GO:0071222//cellular response to lipopolysaccharide;GO:0042593//glucose homeostasis;GO:1990418//response to insulin-like growth factor stimulus;GO:0006914//autophagy;GO:0045348//positive regulation of MHC class II biosynthetic process;GO:1900103//positive regulation of endoplasmic reticulum unfolded protein response;GO:2000347//positive regulation of hepatocyte proliferation;GO:0001935//endothelial cell proliferation;GO:0001525//angiogenesis;GO:0045600//positive regulation of fat cell differentiation;GO:0043066//negative regulation of apoptotic process;GO:0071375//cellular response to peptide hormone stimulus;GO:1990830//cellular response to leukemia inhibitory factor;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:1902236//negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway;GO:0035356//cellular triglyceride homeostasis;GO:0002639//positive regulation of immunoglobulin production;GO:0042149//cellular response to glucose starvation;GO:1901800//positive regulation of proteasomal protein catabolic process;GO:0055089//fatty acid homeostasis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0045582//positive regulation of T cell differentiation;GO:0042632//cholesterol homeostasis;GO:0071353//cellular response to interleukin-4;GO:0010506//regulation of autophagy;GO:0031648//protein destabilization;GO:0001889//liver development;GO:0006990//positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response;GO:0060612//adipose tissue development;GO:0060691//epithelial cell maturation involved in salivary gland development;GO:0071230//cellular response to amino acid stimulus;GO:0035470//positive regulation of vascular wound healing;GO:0031017//exocrine pancreas development;GO:0036500//ATF6-mediated unfolded protein response","K09027//X box-binding protein 1","NP_001073007.1//X-box-binding protein 1 isoform XBP1(S) [Homo sapiens];NP_005071.2//X-box-binding protein 1 isoform XBP1(U) [Homo sapiens]","1//3;3//A2MP1"]
[5646,803,9.45,12.88,0.446746359006182,0.0550690482054275,"*",0.0236286,"PRSS3","GO:1904724//tertiary granule lumen;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005576//extracellular region","GO:0004252//serine-type endopeptidase activity;GO:0005509//calcium ion binding;GO:0008236//serine-type peptidase activity","GO:0006508//proteolysis;GO:0043542//endothelial cell migration;GO:0007586//digestion;GO:0043312//neutrophil degranulation;GO:0031638//zymogen activation;GO:0019730//antimicrobial humoral response;GO:0009235//cobalamin metabolic process","K01312//trypsin [EC:3.4.21.4]","NP_001184026.2//trypsin-3 isoform 3 preproprotein [Homo sapiens];NP_002762.2//trypsin-3 isoform 2 preproprotein [Homo sapiens];NP_031369.2//trypsin-3 isoform 1 preproprotein [Homo sapiens];NP_001184027.1//trypsin-3 isoform 4 preproprotein [Homo sapiens]","1//3;3//A2MP1;2//1"]
[79586,2914,13.48,18.37,0.446531129929491,{"v":9.72662051851852e-07,"d":"9.73E-07"},"*",{"v":1.611158e-07,"d":"1.61E-07"},"CHPF","GO:0005759//mitochondrial matrix;GO:0032580//Golgi cisterna membrane;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0046872//metal ion binding;GO:0047238//glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity;GO:0008376//acetylgalactosaminyltransferase activity;GO:0050510//N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity","GO:0030206//chondroitin sulfate biosynthetic process","K00747//chondroitin polymerizing factor [EC:2.4.1.175 2.4.1.226]","XP_006059009.1//PREDICTED: chondroitin sulfate synthase 2 [Bubalus bubalis];NP_078812.2//chondroitin sulfate synthase 2 isoform 1 [Homo sapiens]","1//3;5"]
[127687,1227,34.53,47.04,0.446037725982978,{"v":4.00485701521217e-07,"d":"4.00E-07"},"*",{"v":6.26276e-08,"d":"6.26E-08"},"C1orf122","NA","NA","NA","K16628//collagen, type VII, alpha;K13172//serine/arginine repetitive matrix protein 2","EAX07314.1//chromosome 1 open reading frame 122, isoform CRA_b, partial [Homo sapiens];EAX07316.1//chromosome 1 open reading frame 122, isoform CRA_d, partial [Homo sapiens]","1//3;2//1"]
[55888,1782,1.74,2.37,0.445799753049531,0.338993664974619,"*",0.204852,"ZKSCAN7","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein;K09229//KRAB and SCAN domains-containing zinc finger protein","XP_011888676.1//PREDICTED: zinc finger protein with KRAB and SCAN domains 7 isoform X3 [Cercocebus atys];XP_004034009.2//PREDICTED: LOW QUALITY PROTEIN: zinc finger protein with KRAB and SCAN domains 7 [Gorilla gorilla gorilla];NP_079445.1//zinc finger protein with KRAB and SCAN domains 7 isoform 2 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[2675,2977,0.47,0.64,0.445411148322363,0.458518621599034,"*",0.309114,"GFRA2","GO:0019898//extrinsic component of membrane;GO:0005622//intracellular;GO:0005886//plasma membrane;GO:0031225//anchored component of membrane","GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0016167//glial cell-derived neurotrophic factor receptor activity","GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0000165//MAPK cascade;GO:0033141//positive regulation of peptidyl-serine phosphorylation of STAT protein;GO:0031953//negative regulation of protein autophosphorylation;GO:0007411//axon guidance","K19895//GDNF family receptor alpha 1","NP_001158510.1//GDNF family receptor alpha-2 isoform b precursor [Homo sapiens];NP_001158511.1//GDNF family receptor alpha-2 isoform c precursor [Homo sapiens];NP_001486.4//GDNF family receptor alpha-2 isoform a preproprotein [Homo sapiens]","1//3;4"]
[101927322,1215,0.94,1.28,0.445411148322363,0.5426633125164,"*",0.388398,"LOC101927322","NA","NA","NA","K07369//mucosa-associated lymphoid tissue lymphoma translocation protein 1 [EC:3.4.22.-]","XP_017384310.1//PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein LOC108304565 [Cebus capucinus imitator]","1//3"]
[9416,3288,41.44,56.42,0.445182662899018,{"v":2.03565678850575E-21,"d":"2.04E-21"},"*",{"v":8.86952e-23,"d":"8.87E-23"},"DDX23","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005682//U5 snRNP;GO:0005737//cytoplasm;GO:0071013//catalytic step 2 spliceosome","GO:0003723//RNA binding;GO:0004004//ATP-dependent RNA helicase activity;GO:0005524//ATP binding;GO:0004386//helicase activity;GO:0003676//nucleic acid binding","GO:0000398//mRNA splicing, via spliceosome;GO:0000354//cis assembly of pre-catalytic spliceosome;GO:0008380//RNA splicing;GO:0010501//RNA secondary structure unwinding;GO:0000375//RNA splicing, via transesterification reactions","K12858//ATP-dependent RNA helicase DDX23/PRP28 [EC:3.6.4.13]","XP_016007227.1//PREDICTED: probable ATP-dependent RNA helicase DDX23 isoform X1 [Rousettus aegyptiacus]","2//1"]
[342977,846,1.08,1.47,0.444784842672896,0.595837935264633,"*",0.439064,"NANOS3","GO:0010494//cytoplasmic stress granule;GO:0005634//nucleus;GO:0000932//P-body;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm","GO:0003723//RNA binding;GO:0008270//zinc ion binding","GO:0048477//oogenesis;GO:0007283//spermatogenesis;GO:0006417//regulation of translation;GO:1900153//positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0007281//germ cell development;GO:0017148//negative regulation of translation;GO:0007275//multicellular organism development;GO:0051726//regulation of cell cycle;GO:2001234//negative regulation of apoptotic signaling pathway","K18761//protein nanos 3","NP_001092092.1//nanos homolog 3 [Homo sapiens]","2//1"]
[84549,3590,14.22,19.35,0.444412101412358,{"v":1.50078457643098e-08,"d":"1.50E-08"},"*",{"v":1.953256e-09,"d":"1.95E-09"},"MAK16","GO:0005730//nucleolus;GO:0030687//preribosome, large subunit precursor","GO:0003723//RNA binding","GO:0000470//maturation of LSU-rRNA;GO:0000460//maturation of 5.8S rRNA","K14831//protein MAK16","XP_012631195.1//protein MAK16 homolog isoform X2 [Microcebus murinus]","3//A2MP1"]
[91355,1997,1.83,2.49,0.444302093784038,0.862206469859001,"*",0.792416,"LRP5L","NA","NA","NA","K03068//low density lipoprotein receptor-related protein 5/6","XP_008965145.1//PREDICTED: low-density lipoprotein receptor-related protein 5-like protein isoform X3 [Pan paniscus];XP_015289840.1//PREDICTED: LOW QUALITY PROTEIN: low-density lipoprotein receptor-related protein 5-like protein [Macaca fascicularis]","1//3;2//1"]
[84299,1506,48.62,66.15,0.44419126313731,{"v":1.23307067795222e-11,"d":"1.23E-11"},"*",{"v":1.130868e-12,"d":"1.13E-12"},"MIEN1","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0031235//intrinsic component of the cytoplasmic side of the plasma membrane","NA","GO:0051491//positive regulation of filopodium assembly;GO:0030335//positive regulation of cell migration;GO:0043066//negative regulation of apoptotic process;GO:0006915//apoptotic process","K07401//selenoprotein W-related protein","EAW60599.1//chromosome 17 open reading frame 37, isoform CRA_b [Homo sapiens];XP_007531013.1//PREDICTED: migration and invasion enhancer 1 [Erinaceus europaeus]","1//3;4"]
[64077,1630,6.47,8.8,0.443737811532152,0.00230633975026015,"*",0.00069375,"LHPP","GO:0005634//nucleus;GO:0005829//cytosol;GO:0016607//nuclear speck","GO:0000287//magnesium ion binding;GO:0101006//protein histidine phosphatase activity;GO:0004427//inorganic diphosphatase activity;GO:0042803//protein homodimerization activity;GO:0016791//phosphatase activity","GO:0006470//protein dephosphorylation;GO:0016311//dephosphorylation;GO:0009168//purine ribonucleoside monophosphate biosynthetic process;GO:0006796//phosphate-containing compound metabolic process","K11725//phospholysine phosphohistidine inorganic pyrophosphate phosphatase [EC:3.6.1.1 3.1.3.-]","XP_010355879.1//PREDICTED: phospholysine phosphohistidine inorganic pyrophosphate phosphatase isoform X3 [Rhinopithecus roxellana];NP_071409.3//phospholysine phosphohistidine inorganic pyrophosphate phosphatase isoform 1 [Homo sapiens];NP_001305260.1//phospholysine phosphohistidine inorganic pyrophosphate phosphatase isoform 3 [Homo sapiens];XP_016871998.1//PREDICTED: phospholysine phosphohistidine inorganic pyrophosphate phosphatase isoform X1 [Homo sapiens]","1//3;3//A2MP1"]
[54,1507,0.25,0.34,0.443606651475615,0.695216835502068,"*",0.578622,"ACP5","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005764//lysosome","GO:0008199//ferric iron binding;GO:0003993//acid phosphatase activity;GO:0008198//ferrous iron binding","GO:0045453//bone resorption;GO:0060349//bone morphogenesis;GO:0034097//response to cytokine;GO:0032695//negative regulation of interleukin-12 production;GO:0032496//response to lipopolysaccharide;GO:0032720//negative regulation of tumor necrosis factor production;GO:0045019//negative regulation of nitric oxide biosynthetic process;GO:0032691//negative regulation of interleukin-1 beta production;GO:0032929//negative regulation of superoxide anion generation;GO:0050728//negative regulation of inflammatory response;GO:0006771//riboflavin metabolic process;GO:0050830//defense response to Gram-positive bacterium","K14379//tartrate-resistant acid phosphatase type 5 [EC:3.1.3.2]","XP_017724910.1//PREDICTED: tartrate-resistant acid phosphatase type 5 isoform X2 [Rhinopithecus bieti]","4;1//3;2//1"]
[8326,2342,1.78,2.42,0.443129806308197,0.165868309477005,"*",0.0855716,"FZD9","GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0009986//cell surface;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0031966//mitochondrial membrane;GO:0031527//filopodium membrane;GO:0005886//plasma membrane","GO:0004888//transmembrane signaling receptor activity;GO:0042813//Wnt-activated receptor activity;GO:0046982//protein heterodimerization activity;GO:0017147//Wnt-protein binding;GO:0042803//protein homodimerization activity;GO:0004930//G-protein coupled receptor activity","GO:0007399//nervous system development;GO:0001503//ossification;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0007405//neuroblast proliferation;GO:0043065//positive regulation of apoptotic process;GO:0030183//B cell differentiation;GO:0071157//negative regulation of cell cycle arrest;GO:0007611//learning or memory;GO:0001836//release of cytochrome c from mitochondria;GO:0035567//non-canonical Wnt signaling pathway;GO:0043524//negative regulation of neuron apoptotic process;GO:0060546//negative regulation of necroptotic process;GO:1901029//negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:2000179//positive regulation of neural precursor cell proliferation;GO:0060070//canonical Wnt signaling pathway;GO:0030501//positive regulation of bone mineralization;GO:0051902//negative regulation of mitochondrial depolarization;GO:0007275//multicellular organism development;GO:0016055//Wnt signaling pathway;GO:1904393//regulation of skeletal muscle acetylcholine-gated channel clustering;GO:1904394//negative regulation of skeletal muscle acetylcholine-gated channel clustering;GO:1990523//bone regeneration","K02842//frizzled 9/10","XP_011765634.1//PREDICTED: frizzled-9 [Macaca nemestrina]","2//1"]
[389541,615,45.44,61.77,0.442943495848729,2.23608325299363E-4,"*",{"v":5.49432e-05,"d":"5.49E-05"},"LAMTOR4","GO:0071986//Ragulator complex","NA","GO:0032008//positive regulation of TOR signaling;GO:0071230//cellular response to amino acid stimulus","K20399//ragulator complex protein LAMTOR4","XP_005413797.1//PREDICTED: ragulator complex protein LAMTOR4 isoform X2 [Chinchilla lanigera];XP_013850875.1//ragulator complex protein LAMTOR4 isoform X6 [Sus scrofa];XP_013364922.1//PREDICTED: ragulator complex protein LAMTOR4 isoform X1 [Chinchilla lanigera]","1//3;3//A2MP1"]
[4282,561,910.76,1237.87,0.442716976234977,{"v":5.51408589565217e-72,"d":"5.51E-72"},"*",{"v":4.76364E-74,"d":"4.76E-74"},"MIF","GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome;GO:0005654//nucleoplasm;GO:0005615//extracellular space;GO:0043209//myelin sheath;GO:0005737//cytoplasm;GO:0031982//vesicle;GO:0009986//cell surface;GO:0005829//cytosol;GO:0005576//extracellular region;GO:1904813//ficolin-1-rich granule lumen","GO:0002020//protease binding;GO:0050178//phenylpyruvate tautomerase activity;GO:0005125//cytokine activity;GO:0042802//identical protein binding;GO:0004167//dopachrome isomerase activity;GO:0005102//receptor binding;GO:0042056//chemoattractant activity;GO:0005126//cytokine receptor binding","GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0010760//negative regulation of macrophage chemotaxis;GO:0043030//regulation of macrophage activation;GO:0007166//cell surface receptor signaling pathway;GO:0030890//positive regulation of B cell proliferation;GO:0032760//positive regulation of tumor necrosis factor production;GO:0071157//negative regulation of cell cycle arrest;GO:0001516//prostaglandin biosynthetic process;GO:0061081//positive regulation of myeloid leukocyte cytokine production involved in immune response;GO:0002906//negative regulation of mature B cell apoptotic process;GO:0045087//innate immune response;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0010739//positive regulation of protein kinase A signaling;GO:0048146//positive regulation of fibroblast proliferation;GO:0043066//negative regulation of apoptotic process;GO:0042327//positive regulation of phosphorylation;GO:1902166//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0061078//positive regulation of prostaglandin secretion involved in immune response;GO:0010629//negative regulation of gene expression;GO:0031666//positive regulation of lipopolysaccharide-mediated signaling pathway;GO:0043518//negative regulation of DNA damage response, signal transduction by p53 class mediator;GO:0008283//cell proliferation;GO:0043312//neutrophil degranulation;GO:0033033//negative regulation of myeloid cell apoptotic process;GO:0070207//protein homotrimerization;GO:0035722//interleukin-12-mediated signaling pathway;GO:0050900//leukocyte migration;GO:0007569//cell aging;GO:0043406//positive regulation of MAP kinase activity;GO:0032269//negative regulation of cellular protein metabolic process;GO:0006954//inflammatory response;GO:0090344//negative regulation of cell aging;GO:0019752//carboxylic acid metabolic process;GO:2000343//positive regulation of chemokine (C-X-C motif) ligand 2 production;GO:0050715//positive regulation of cytokine secretion;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0090238//positive regulation of arachidonic acid secretion","K07253//phenylpyruvate tautomerase [EC:5.3.2.1]","NP_002406.1//macrophage migration inhibitory factor [Homo sapiens]","1//3"]
[130617,1118,14.73,20.02,0.442684543800144,0.00544016151501155,"*",1.769568E-3,"ZFAND2B","GO:0005783//endoplasmic reticulum","GO:0008270//zinc ion binding","GO:0006616//SRP-dependent cotranslational protein targeting to membrane, translocation","K07059//uncharacterized protein","NP_620157.1//AN1-type zinc finger protein 2B isoform 1 [Homo sapiens];XP_011918237.1//PREDICTED: AN1-type zinc finger protein 2B isoform X2 [Cercocebus atys];XP_007964535.1//PREDICTED: AN1-type zinc finger protein 2B isoform X4 [Chlorocebus sabaeus]","1//3;2//1"]
[81894,1584,26.17,35.56,0.442341399781735,{"v":6.10744476712329e-07,"d":"6.11E-07"},"*",{"v":9.7687e-08,"d":"9.77E-08"},"SLC25A28","GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion","GO:0005381//iron ion transmembrane transporter activity","GO:0006810//transport;GO:0048250//mitochondrial iron ion transport;GO:0055072//iron ion homeostasis;GO:0006839//mitochondrial transport","K15113//solute carrier family 25 (mitochondrial iron transporter), member 28/37","AAH47312.1//SLC25A28 protein, partial [Homo sapiens]","3//A2MP1"]
[25864,1118,13.74,18.67,0.442339923408102,4.14151544310787E-3,"*",1.314738E-3,"ABHD14A","GO:0070062//extracellular exosome;GO:0016021//integral component of membrane;GO:0005737//cytoplasm","GO:0016787//hydrolase activity","NA","K13706//abhydrolase domain-containing protein 14","XP_003950172.2//PREDICTED: protein ABHD14A isoform X1 [Pan troglodytes]",4]
[125919,3671,1.31,1.78,0.442310429428948,0.129803917767015,"*",0.0637562,"ZNF543","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","XP_021787176.1//zinc finger protein 805 isoform X1 [Papio anubis]","3//A2MP1"]
[23550,5039,2.76,3.75,0.442222328605074,0.00566012373210516,"*",0.001846432,"PSD4","NA","NA","NA","K12494//PH and SEC7 domain-containing protein","XP_016804757.1//PREDICTED: PH and SEC7 domain-containing protein 4 isoform X1 [Pan troglodytes]","2//1"]
[4728,824,193.73,263.2,0.442112109732235,{"v":1.57847133202614e-23,"d":"1.58E-23"},"*",{"v":6.04748e-25,"d":"6.05E-25"},"NDUFS8","GO:0016020//membrane;GO:0005759//mitochondrial matrix;GO:0005747//mitochondrial respiratory chain complex I;GO:0005739//mitochondrion","GO:0016651//oxidoreductase activity, acting on NAD(P)H;GO:0046872//metal ion binding;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0008137//NADH dehydrogenase (ubiquinone) activity","GO:0006979//response to oxidative stress;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0006120//mitochondrial electron transport, NADH to ubiquinone","K03941//NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:1.6.5.3 1.6.99.3]","NP_002487.1//NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial precursor [Homo sapiens]","3//A2MP1"]
[728441,2583,3.35,4.55,0.441705449740924,0.0347636810871253,"*",0.01401298,"GGT2","NA","NA","NA","K18592//gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]","NP_001338233.1//inactive gamma-glutamyltranspeptidase 2 precursor [Homo sapiens]","1//3"]
[124944,893,79.82,108.36,0.441010114690743,{"v":5.29232038895282e-10,"d":"5.29E-10"},"*",{"v":5.75814e-11,"d":"5.76E-11"},"C17orf49","GO:0005654//nucleoplasm;GO:0071339//MLL1 complex;GO:0016589//NURF complex;GO:0005829//cytosol","GO:0003677//DNA binding","GO:0016569//covalent chromatin modification","NA","XP_017387237.1//PREDICTED: chromatin complexes subunit BAP18 isoform X4 [Cebus capucinus imitator];XP_012632717.1//chromatin complexes subunit BAP18 isoform X1 [Microcebus murinus];XP_017387234.1//PREDICTED: chromatin complexes subunit BAP18 isoform X1 [Cebus capucinus imitator]","3//A2MP1;2//1"]
[390,2749,13.09,17.77,0.440978584083437,{"v":5.03863447169811e-06,"d":"5.04E-06"},"*",{"v":9.36188e-07,"d":"9.36E-07"},"RND3","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005925//focal adhesion;GO:0005622//intracellular;GO:0005886//plasma membrane;GO:0000139//Golgi membrane","GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0007155//cell adhesion;GO:0030036//actin cytoskeleton organization;GO:0007264//small GTPase mediated signal transduction","K07859//Rho family GTPase 3","NP_005159.1//rho-related GTP-binding protein RhoE precursor [Homo sapiens]","4;1//3"]
[440712,1684,0.14,0.19,0.440572591385981,0.782591323521006,"*",0.685686,"RHEX","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","NA","NA","NA","NP_001007545.1//uncharacterized protein C1orf186 [Homo sapiens]","3//A2MP1"]
[1909,2132,0.14,0.19,0.440572591385981,0.734684326992288,"*",0.626188,"EDNRA","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004435//phosphatidylinositol phospholipase C activity;GO:0004962//endothelin receptor activity","GO:0008217//regulation of blood pressure;GO:0042310//vasoconstriction;GO:0008283//cell proliferation;GO:0030818//negative regulation of cAMP biosynthetic process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0014032//neural crest cell development;GO:0007585//respiratory gaseous exchange;GO:0007165//signal transduction;GO:0007507//heart development;GO:0006939//smooth muscle contraction;GO:0001701//in utero embryonic development;GO:0001666//response to hypoxia;GO:0015758//glucose transport;GO:0048484//enteric nervous system development;GO:0007190//activation of adenylate cyclase activity;GO:0060322//head development;GO:0007202//activation of phospholipase C activity;GO:0014824//artery smooth muscle contraction;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0001569//branching involved in blood vessel morphogenesis","K04197//endothelin receptor type A","NP_001341726.1//endothelin-1 receptor isoform d precursor [Homo sapiens];NP_001159527.1//endothelin-1 receptor isoform b precursor [Homo sapiens];NP_001948.1//endothelin-1 receptor isoform a precursor [Homo sapiens]","1//3;3//A2MP1"]
[23237,2948,0.14,0.19,0.440572591385981,0.695740145126082,"*",0.578622,"ARC","GO:0030054//cell junction;GO:0001669//acrosomal vesicle;GO:0014069//postsynaptic density;GO:0005737//cytoplasm;GO:0043025//neuronal cell body;GO:0005768//endosome;GO:0015629//actin cytoskeleton;GO:0043197//dendritic spine;GO:0005886//plasma membrane;GO:0045211//postsynaptic membrane","NA","GO:0007492//endoderm development;GO:0009952//anterior/posterior pattern specification;GO:1900271//regulation of long-term synaptic potentiation;GO:0016477//cell migration;GO:0061001//regulation of dendritic spine morphogenesis;GO:0007612//learning;GO:2000969//positive regulation of AMPA receptor activity;GO:0007616//long-term memory;GO:0060997//dendritic spine morphogenesis;GO:0048168//regulation of neuronal synaptic plasticity;GO:0060291//long-term synaptic potentiation;GO:0007010//cytoskeleton organization;GO:0006897//endocytosis;GO:0022604//regulation of cell morphogenesis","K15867//activity-regulated cytoskeleton-associated protein","NP_056008.1//activity-regulated cytoskeleton-associated protein [Homo sapiens]",4]
[448831,2084,0.28,0.38,0.440572591385981,0.734360701270098,"*",0.626188,"FRG2","GO:0005634//nucleus","NA","NA","K22069//LYR motif-containing protein 4;K11447//histone demethylase [EC:1.14.11.-];K15696//RING finger protein 113B;K17985//activating molecule in BECN1-regulated autophagy protein 1;K18047//serine/threonine/tyrosine-interacting-like protein 1","NP_001005217.1//protein FRG2 isoform 2 [Homo sapiens];NP_001273749.1//protein FRG2 isoform 1 [Homo sapiens]","1//3"]
[55824,10759,0.14,0.19,0.440572591385981,0.434347554423694,"*",0.288278,"PAG1","GO:0045121//membrane raft;GO:0005887//integral component of plasma membrane;GO:0005622//intracellular;GO:0005886//plasma membrane","GO:0005070//SH3/SH2 adaptor activity;GO:0005068//transmembrane receptor protein tyrosine kinase adaptor activity;GO:0042169//SH2 domain binding","GO:0050863//regulation of T cell activation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007165//signal transduction;GO:0050852//T cell receptor signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0050868//negative regulation of T cell activation;GO:0035556//intracellular signal transduction;GO:0002250//adaptive immune response","K12581//CCR4-NOT transcription complex subunit 7/8;K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K15696//RING finger protein 113B;K17985//activating molecule in BECN1-regulated autophagy protein 1","NP_060910.3//phosphoprotein associated with glycosphingolipid-enriched microdomains 1 [Homo sapiens]","3//A2MP1"]
[5002,1492,21.86,29.66,0.440225196782726,{"v":4.960284967171e-05,"d":"4.96E-05"},"*",{"v":1.08776e-05,"d":"1.09E-05"},"SLC22A18","GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0005635//nuclear envelope;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0015307//drug:proton antiporter activity;GO:0031625//ubiquitin protein ligase binding;GO:0015238//drug transmembrane transporter activity;GO:0015293//symporter activity;GO:0005215//transporter activity","GO:0015695//organic cation transport;GO:0055085//transmembrane transport;GO:0015893//drug transport;GO:0007588//excretion","K08214//MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 18","NP_001302431.1//solute carrier family 22 member 18 isoform c [Homo sapiens];NP_001302430.1//solute carrier family 22 member 18 isoform a [Homo sapiens]","1//3;2//1;5"]
[8721,748,180.77,245.23,0.439980208024017,{"v":6.71454580240964e-19,"d":"6.71E-19"},"*",{"v":3.48884e-20,"d":"3.49E-20"},"EDF1","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005737//cytoplasm;GO:0005669//transcription factor TFIID complex","GO:0003723//RNA binding;GO:0003713//transcription coactivator activity;GO:0043565//sequence-specific DNA binding;GO:0005516//calmodulin binding","GO:0030154//cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0007275//multicellular organism development;GO:0045446//endothelial cell differentiation;GO:0019216//regulation of lipid metabolic process;GO:0043388//positive regulation of DNA binding","K03627//putative transcription factor","XP_003480683.2//endothelial differentiation-related factor 1 [Sus scrofa];NP_001268226.1//endothelial differentiation-related factor 1 isoform 3 [Homo sapiens];XP_012364470.1//PREDICTED: endothelial differentiation-related factor 1 isoform X1 [Nomascus leucogenys]","1//3;3//A2MP1;2//1"]
[3163,1789,28.79,39.05,0.439754759465907,{"v":4.43562319777159e-07,"d":"4.44E-07"},"*",{"v":6.97804e-08,"d":"6.98E-08"},"HMOX2","GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane","GO:0046872//metal ion binding;GO:0020037//heme binding;GO:0004392//heme oxygenase (decyclizing) activity","GO:0006979//response to oxidative stress;GO:0042167//heme catabolic process;GO:0006879//cellular iron ion homeostasis;GO:0055072//iron ion homeostasis;GO:0006788//heme oxidation;GO:0043312//neutrophil degranulation;GO:0001666//response to hypoxia","K21418//heme oxygenase 2 [EC:1.14.14.18]","NP_002125.3//heme oxygenase 2 isoform b [Homo sapiens];NP_001273196.1//heme oxygenase 2 isoform a [Homo sapiens];XP_009428495.1//PREDICTED: heme oxygenase 2 isoform X1 [Pan troglodytes];XP_008966249.2//PREDICTED: heme oxygenase 2 isoform X1 [Pan paniscus]","1//3;3//A2MP1;2//1"]
[51149,1133,44.99,61.02,0.43967781299961,{"v":1.65050257420719e-07,"d":"1.65E-07"},"*",{"v":2.44362e-08,"d":"2.44E-08"},"MRNIP","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0030870//Mre11 complex","GO:0003682//chromatin binding","GO:0010212//response to ionizing radiation;GO:0071168//protein localization to chromatin;GO:0007095//mitotic G2 DNA damage checkpoint;GO:0006281//DNA repair;GO:2001032//regulation of double-strand break repair via nonhomologous end joining;GO:1905168//positive regulation of double-strand break repair via homologous recombination;GO:0045860//positive regulation of protein kinase activity;GO:0006974//cellular response to DNA damage stimulus","NA","NP_057259.2//MRN complex-interacting protein isoform 1 [Homo sapiens];NP_001017987.1//MRN complex-interacting protein isoform 2 [Homo sapiens]","3//A2MP1;2//1"]
[130612,2362,0.73,0.99,0.439532061199592,0.410754757036186,"*",0.268608,"TMEM198","GO:0031410//cytoplasmic vesicle;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","NA","GO:0007275//multicellular organism development;GO:0016055//Wnt signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway","K16628//collagen, type VII, alpha;K17501//protein phosphatase 1E [EC:3.1.3.16];K00747//chondroitin polymerizing factor [EC:2.4.1.175 2.4.1.226]","XP_001494200.3//PREDICTED: transmembrane protein 198 isoform X1 [Equus caballus];NP_001005209.1//transmembrane protein 198 [Homo sapiens]","1//3;2//1"]
[150678,456,36.75,49.83,0.439270324072443,0.00394168491071075,"*",0.001246366,"COPS9","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0008180//COP9 signalosome;GO:0000790//nuclear chromatin;GO:0005737//cytoplasm","NA","GO:0051220//cytoplasmic sequestering of protein;GO:0034644//cellular response to UV;GO:2000435//negative regulation of protein neddylation;GO:0008284//positive regulation of cell proliferation","NA","XP_008963886.1//PREDICTED: myeloma-overexpressed gene 2 protein isoform X2 [Pan paniscus];NP_612209.1//COP9 signalosome complex subunit 9 isoform 1 [Homo sapiens]","1//3"]
[11094,2687,3.43,4.65,0.439022139822581,0.0204730688659794,"*",0.00770784,"CACFD1","GO:0016021//integral component of membrane","NA","GO:0016192//vesicle-mediated transport","K08627//a disintegrin and metalloproteinase with thrombospondin motifs 13 [EC:3.4.24.87];K22125//myoferlin","XP_018888693.1//PREDICTED: uncharacterized protein LOC109028208 [Gorilla gorilla gorilla];XP_008003971.1//PREDICTED: calcium channel flower homolog isoform X3 [Chlorocebus sabaeus];XP_012300572.1//calcium channel flower homolog [Aotus nancymaae]","1//3;3//A2MP1;2//1"]
[5554,1052,3.38,4.58,0.43832435181476,0.330796817342366,"*",0.1986976,"PRH1","NA","NA","NA","K13910//salivary acidic proline-rich phosphoprotein 1/2","XP_018894118.1//PREDICTED: salivary acidic proline-rich phosphoprotein 1/2 [Gorilla gorilla gorilla];NP_001278244.1//salivary acidic proline-rich phosphoprotein 1/2 isoform b [Homo sapiens]","1//3"]
[26093,2093,10.01,13.56,0.43791520430035,0.000592873661350844,"*",0.000158258,"CCDC9","NA","NA","NA","K22020//mucin-19;K19607//X-linked retinitis pigmentosa GTPase regulator","XP_008965001.1//PREDICTED: coiled-coil domain-containing protein 9 isoform X3 [Pan paniscus]","2//1"]
[10400,953,61.45,83.24,0.437863954475311,{"v":1.42777434951644E-8,"d":"1.43E-08"},"*",{"v":1.848402E-9,"d":"1.85E-09"},"PEMT","GO:0031526//brush border membrane;GO:0042383//sarcolemma;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0005789//endoplasmic reticulum membrane","GO:0004608//phosphatidylethanolamine N-methyltransferase activity;GO:0080101//phosphatidyl-N-dimethylethanolamine N-methyltransferase activity;GO:0008429//phosphatidylethanolamine binding;GO:0000773//phosphatidyl-N-methylethanolamine N-methyltransferase activity","GO:0042493//response to drug;GO:0043200//response to amino acid;GO:0046498//S-adenosylhomocysteine metabolic process;GO:1903955//positive regulation of protein targeting to mitochondrion;GO:0046500//S-adenosylmethionine metabolic process;GO:0006686//sphingomyelin biosynthetic process;GO:0045471//response to ethanol;GO:0008283//cell proliferation;GO:0050747//positive regulation of lipoprotein metabolic process;GO:0033273//response to vitamin;GO:0006656//phosphatidylcholine biosynthetic process;GO:0006629//lipid metabolic process;GO:0008285//negative regulation of cell proliferation","K00551//phosphatidylethanolamine N-methyltransferase [EC:2.1.1.17]","NP_001254481.1//phosphatidylethanolamine N-methyltransferase isoform 3 [Homo sapiens];NP_680477.1//phosphatidylethanolamine N-methyltransferase isoform 1 [Homo sapiens];NP_001254480.1//phosphatidylethanolamine N-methyltransferase isoform 4 [Homo sapiens]","1//3;2//1"]
[114789,3372,5.36,7.26,0.437736547537978,2.04728837305263E-3,"*",0.000608778,"SLC25A25","GO:0070062//extracellular exosome;GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion","GO:0005347//ATP transmembrane transporter activity;GO:0015217//ADP transmembrane transporter activity;GO:0005509//calcium ion binding","GO:0070588//calcium ion transmembrane transport;GO:0046034//ATP metabolic process;GO:0055085//transmembrane transport;GO:0043010//camera-type eye development;GO:0014823//response to activity;GO:0032094//response to food;GO:0002021//response to dietary excess;GO:0060612//adipose tissue development;GO:0006839//mitochondrial transport;GO:0035264//multicellular organism growth;GO:0045333//cellular respiration","K14684//solute carrier family 25 (mitochondrial phosphate transporter), member 23/24/25/41","XP_001362766.1//PREDICTED: calcium-binding mitochondrial carrier protein SCaMC-2 isoform X1 [Monodelphis domestica];XP_005908520.1//PREDICTED: calcium-binding mitochondrial carrier protein SCaMC-2 isoform X3 [Bos mutus];XP_003407751.1//PREDICTED: calcium-binding mitochondrial carrier protein SCaMC-2 isoform X1 [Loxodonta africana];XP_011362527.1//PREDICTED: calcium-binding mitochondrial carrier protein SCaMC-2 isoform X2 [Pteropus vampyrus];XP_011362528.1//PREDICTED: calcium-binding mitochondrial carrier protein SCaMC-2 isoform X3 [Pteropus vampyrus]","4;1//3;3//A2MP1;2//1"]
[2531,5198,7.99,10.82,0.437433090898838,{"v":6.07332355973365e-07,"d":"6.07E-07"},"*",{"v":9.70652E-8,"d":"9.71E-08"},"KDSR","GO:0016020//membrane;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0047560//3-dehydrosphinganine reductase activity;GO:0016491//oxidoreductase activity","GO:0030148//sphingolipid biosynthetic process;GO:0006666//3-keto-sphinganine metabolic process","K04708//3-dehydrosphinganine reductase [EC:1.1.1.102]","NP_002026.1//3-ketodihydrosphingosine reductase precursor [Homo sapiens]","2//1"]
[4162,3332,1.84,2.49,0.436439976011068,0.0796771950610433,"*",0.035953,"MCAM","GO:0005634//nucleus;GO:0005615//extracellular space;GO:0005925//focal adhesion;GO:0009897//external side of plasma membrane;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane","NA","GO:0061042//vascular wound healing;GO:0007155//cell adhesion;GO:0009653//anatomical structure morphogenesis;GO:0030335//positive regulation of cell migration;GO:0003094//glomerular filtration;GO:0001525//angiogenesis","K06534//melanoma cell adhesion molecule","BAD93162.1//Melanoma cell adhesion molecule variant, partial [Homo sapiens]","2//1"]
[157807,3506,12.57,17.01,0.436398491242877,{"v":2.995614e-07,"d":"3.00E-07"},"*",{"v":4.5945e-08,"d":"4.59E-08"},"CLVS1","GO:0005768//endosome;GO:0032588//trans-Golgi network membrane;GO:0031901//early endosome membrane;GO:0030136//clathrin-coated vesicle;GO:0005802//trans-Golgi network;GO:0030669//clathrin-coated endocytic vesicle membrane","GO:0080025//phosphatidylinositol-3,5-bisphosphate binding;GO:0005215//transporter activity","GO:0007040//lysosome organization","K19625//retinaldehyde-binding protein 1","NP_775790.1//clavesin-1 [Homo sapiens]","2//1"]
[23309,5061,8.72,11.8,0.436386819472277,{"v":5.65749402144772e-06,"d":"5.66E-06"},"*",{"v":1.05684E-6,"d":"1.06E-06"},"SIN3B","GO:0030849//autosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000805//X chromosome;GO:0016580//Sin3 complex;GO:0001741//XY body;GO:0005737//cytoplasm;GO:0000806//Y chromosome","GO:0001106//RNA polymerase II transcription corepressor activity;GO:0003714//transcription corepressor activity;GO:0003682//chromatin binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006355//regulation of transcription, DNA-templated;GO:0019216//regulation of lipid metabolic process;GO:0006351//transcription, DNA-templated;GO:0016575//histone deacetylation","K11644//paired amphipathic helix protein Sin3a","NP_001284524.1//paired amphipathic helix protein Sin3b isoform 2 [Homo sapiens];NP_056075.1//paired amphipathic helix protein Sin3b isoform 1 [Homo sapiens];XP_018871745.1//PREDICTED: paired amphipathic helix protein Sin3b [Gorilla gorilla gorilla]","1//3;3//A2MP1"]
[1545,5160,25.33,34.27,0.436099114806674,{"v":7.62672486153846e-20,"d":"7.63E-20"},"*",{"v":3.72408e-21,"d":"3.72E-21"},"CYP1B1","GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0005739//mitochondrion;GO:0005789//endoplasmic reticulum membrane","GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0020037//heme binding;GO:0005506//iron ion binding;GO:0070330//aromatase activity;GO:0004497//monooxygenase activity;GO:0019825//oxygen binding;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen","GO:0019369//arachidonic acid metabolic process;GO:0061304//retinal blood vessel morphogenesis;GO:0030199//collagen fibril organization;GO:0006725//cellular aromatic compound metabolic process;GO:0007601//visual perception;GO:0071603//endothelial cell-cell adhesion;GO:0043065//positive regulation of apoptotic process;GO:0016125//sterol metabolic process;GO:0045766//positive regulation of angiogenesis;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0008285//negative regulation of cell proliferation;GO:0070301//cellular response to hydrogen peroxide;GO:0001525//angiogenesis;GO:0043542//endothelial cell migration;GO:0002930//trabecular meshwork development;GO:0006805//xenobiotic metabolic process;GO:0007155//cell adhesion;GO:0048514//blood vessel morphogenesis;GO:0008210//estrogen metabolic process;GO:0046466//membrane lipid catabolic process;GO:0009404//toxin metabolic process;GO:0010575//positive regulation of vascular endothelial growth factor production;GO:0042574//retinal metabolic process;GO:0055114//oxidation-reduction process;GO:0009636//response to toxic substance;GO:0046427//positive regulation of JAK-STAT cascade;GO:0008202//steroid metabolic process;GO:0071407//cellular response to organic cyclic compound;GO:0097267//omega-hydroxylase P450 pathway;GO:0019373//epoxygenase P450 pathway;GO:0033629//negative regulation of cell adhesion mediated by integrin;GO:0008631//intrinsic apoptotic signaling pathway in response to oxidative stress;GO:0042572//retinol metabolic process;GO:0030336//negative regulation of cell migration;GO:2000377//regulation of reactive oxygen species metabolic process;GO:0006809//nitric oxide biosynthetic process","K07410//cytochrome P450 family 1 subfamily B polypeptide 1 [EC:1.14.14.1]","NP_000095.2//cytochrome P450 1B1 [Homo sapiens]","3//A2MP1"]
[151306,1627,0.17,0.23,0.436099114806673,0.831130183882581,"*",0.751524,"GPBAR1","GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0038181//bile acid receptor activity;GO:0038182//G-protein coupled bile acid receptor activity;GO:0004930//G-protein coupled receptor activity","GO:2000810//regulation of bicellular tight junction assembly;GO:0038184//cell surface bile acid receptor signaling pathway","K08400//G protein-coupled bile acid receptor 1","XP_003907996.2//G-protein coupled bile acid receptor 1 isoform X1 [Papio anubis];XP_007964435.1//PREDICTED: G-protein coupled bile acid receptor 1 isoform X2 [Chlorocebus sabaeus]","1//3;2//1"]
[10610,2105,0.34,0.46,0.436099114806673,0.641333181425486,"*",0.520486,"ST6GALNAC2","GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0008373//sialyltransferase activity;GO:0001665//alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity","GO:0006486//protein glycosylation;GO:0018279//protein N-linked glycosylation via asparagine;GO:0009311//oligosaccharide metabolic process;GO:0097503//sialylation;GO:0016266//O-glycan processing","K06616//alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase (sialyltransferase 7B) [EC:2.4.99.-]","NP_006447.2//alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 precursor [Homo sapiens]","2//1"]
[2852,2693,0.17,0.23,0.436099114806673,0.718408161868631,"*",0.60458,"GPER1","GO:0030424//axon;GO:0005783//endoplasmic reticulum;GO:0005635//nuclear envelope;GO:0030054//cell junction;GO:0005802//trans-Golgi network;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0016021//integral component of membrane;GO:0045095//keratin filament;GO:0043679//axon terminus;GO:0055037//recycling endosome;GO:0005886//plasma membrane;GO:0005769//early endosome;GO:0030659//cytoplasmic vesicle membrane","GO:0030284//estrogen receptor activity;GO:0003682//chromatin binding;GO:0017082//mineralocorticoid receptor activity;GO:1990239//steroid hormone binding;GO:0004930//G-protein coupled receptor activity","GO:0030335//positive regulation of cell migration;GO:0071356//cellular response to tumor necrosis factor;GO:0050728//negative regulation of inflammatory response;GO:1903078//positive regulation of protein localization to plasma membrane;GO:0045742//positive regulation of epidermal growth factor receptor signaling pathway;GO:0071157//negative regulation of cell cycle arrest;GO:0051898//negative regulation of protein kinase B signaling;GO:0030819//positive regulation of cAMP biosynthetic process;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0045599//negative regulation of fat cell differentiation;GO:0071375//cellular response to peptide hormone stimulus;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0071333//cellular response to glucose stimulus;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0032962//positive regulation of inositol trisphosphate biosynthetic process;GO:0002695//negative regulation of leukocyte activation;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0051055//negative regulation of lipid biosynthetic process;GO:0032024//positive regulation of insulin secretion;GO:0010629//negative regulation of gene expression;GO:1904706//negative regulation of vascular smooth muscle cell proliferation;GO:0070474//positive regulation of uterine smooth muscle contraction;GO:2000724//positive regulation of cardiac vascular smooth muscle cell differentiation;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0045745//positive regulation of G-protein coupled receptor protein signaling pathway;GO:0050769//positive regulation of neurogenesis;GO:0030263//apoptotic chromosome condensation;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0007049//cell cycle;GO:0071392//cellular response to estradiol stimulus;GO:0008284//positive regulation of cell proliferation","K04246//G protein-coupled receptor 30","NP_001496.1//G-protein coupled estrogen receptor 1 [Homo sapiens]","1//3;2//1"]
[26240,1673,2.07,2.8,0.435796059445641,0.239951739437249,"*",0.1345316,"FAM50B","GO:0045171//intercellular bridge;GO:0005634//nucleus;GO:0005654//nucleoplasm","NA","NA","K13119//protein FAM50","NP_036267.1//protein FAM50B [Homo sapiens]","2//1"]
[57194,5235,1.9,2.57,0.43576894086293,0.025962641053482,"*",0.01005902,"ATP10A","GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane","GO:0000287//magnesium ion binding;GO:0005524//ATP binding;GO:0004012//phospholipid-translocating ATPase activity","GO:0045332//phospholipid translocation;GO:0034220//ion transmembrane transport;GO:0008360//regulation of cell shape","K01530//phospholipid-translocating ATPase [EC:3.6.3.1]","NP_077816.1//probable phospholipid-transporting ATPase VA [Homo sapiens]","3//A2MP1"]
[50512,2209,7.8,10.55,0.435696969844937,0.00222333007054895,"*",0.000666832,"PODXL2","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005796//Golgi lumen","GO:0005539//glycosaminoglycan binding","GO:0050901//leukocyte tethering or rolling;GO:0050427//3'-phosphoadenosine 5'-phosphosulfate metabolic process","K06818//podocalyxin-like 2","NP_056535.1//podocalyxin-like protein 2 precursor [Homo sapiens]","3//A2MP1"]
[55520,2233,1.22,1.65,0.43558487668293,0.304487917685845,"*",0.179235,"ELAC1","GO:0005634//nucleus;GO:0005829//cytosol","GO:0046872//metal ion binding;GO:0016891//endoribonuclease activity, producing 5'-phosphomonoesters;GO:0042781//3'-tRNA processing endoribonuclease activity","GO:0042779//tRNA 3'-trailer cleavage","K00784//ribonuclease Z [EC:3.1.26.11]","NP_061166.1//zinc phosphodiesterase ELAC protein 1 [Homo sapiens]","2//1"]
[730098,1532,3.01,4.07,0.435265307506545,0.161158916290971,"*",0.082799,"LOC730098","NA","NA","NA","K16598//C-C motif chemokine 27","AAH37171.1//Unknown (protein for IMAGE:5248278), partial [Homo sapiens];XP_010384105.1//PREDICTED: uncharacterized protein LOC104680017 [Rhinopithecus roxellana]","1//3"]
[6231,1203,346.99,469.18,0.43524743012495,{"v":1.05940644898876e-59,"d":"1.06E-59"},"*",{"v":1.180508e-61,"d":"1.18E-61"},"RPS26","NA","NA","NA","K02976//small subunit ribosomal protein S26e","XP_005335675.1//40S ribosomal protein S26 [Ictidomys tridecemlineatus]",4]
[84876,1496,43.62,58.98,0.435236052420986,{"v":4.53445885913853E-10,"d":"4.53E-10"},"*",{"v":4.8768e-11,"d":"4.88E-11"},"ORAI1","GO:0016323//basolateral plasma membrane;GO:0016020//membrane;GO:0005887//integral component of plasma membrane;GO:0043234//protein complex;GO:0016021//integral component of membrane","GO:0015279//store-operated calcium channel activity;GO:0042802//identical protein binding;GO:0005516//calmodulin binding","GO:0061180//mammary gland epithelium development;GO:0051924//regulation of calcium ion transport;GO:0070509//calcium ion import;GO:0002115//store-operated calcium entry;GO:0051928//positive regulation of calcium ion transport;GO:0002250//adaptive immune response","K16056//calcium release-activated calcium channel protein 1","NP_116179.2//calcium release-activated calcium channel protein 1 [Homo sapiens]","3//A2MP1"]
[100293516,3356,4.09,5.53,0.435178637292958,0.00684407324538259,"*",0.00227336,"ZNF587B","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_011835096.1//PREDICTED: LOW QUALITY PROTEIN: putative uncharacterized zinc finger protein 814 [Mandrillus leucophaeus]","1//3"]
[7769,2269,5.2,7.03,0.435013066044081,0.331412930612245,"*",0.1992544,"ZNF226","GO:0005634//nucleus;GO:0005622//intracellular","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","NP_001027544.1//zinc finger protein 226 isoform a [Homo sapiens];XP_004091064.1//PREDICTED: zinc finger protein 226 isoform X3 [Nomascus leucogenys]","1//3;3//A2MP1;2//1"]
[9533,1309,22.88,30.93,0.434919781310875,{"v":5.86256169799605e-05,"d":"5.86E-05"},"*",{"v":1.300304E-5,"d":"1.30E-05"},"POLR1C","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005666//DNA-directed RNA polymerase III complex;GO:0005736//DNA-directed RNA polymerase I complex","GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0003677//DNA binding;GO:0046983//protein dimerization activity","GO:0006363//termination of RNA polymerase I transcription;GO:0006362//transcription elongation from RNA polymerase I promoter;GO:0032481//positive regulation of type I interferon production;GO:0045815//positive regulation of gene expression, epigenetic;GO:0006361//transcription initiation from RNA polymerase I promoter;GO:0006360//transcription from RNA polymerase I promoter;GO:0006351//transcription, DNA-templated;GO:0006383//transcription from RNA polymerase III promoter","K03027//DNA-directed RNA polymerases I and III subunit RPAC1","NP_001305805.1//DNA-directed RNA polymerases I and III subunit RPAC1 isoform 2 [Homo sapiens];XP_007970669.1//PREDICTED: DNA-directed RNA polymerases I and III subunit RPAC1 [Chlorocebus sabaeus]","1//3;3//A2MP1"]
[29095,1361,29.85,40.35,0.434837742012975,{"v":1.36488758564558e-06,"d":"1.36E-06"},"*",{"v":2.30956e-07,"d":"2.31E-07"},"ORMDL2","GO:0035339//SPOTS complex;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane","NA","GO:0090156//cellular sphingolipid homeostasis;GO:1900060//negative regulation of ceramide biosynthetic process;GO:0006672//ceramide metabolic process","NA","XP_010348246.1//PREDICTED: ORM1-like protein 2 [Saimiri boliviensis boliviensis]",4]
[7031,508,2.9,3.92,0.434800754100274,0.498836129719964,"*",0.345694,"TFF1","GO:0005615//extracellular space","GO:0008083//growth factor activity","GO:0030154//cell differentiation;GO:0007586//digestion;GO:0042060//wound healing;GO:0043434//response to peptide hormone;GO:0010039//response to iron ion;GO:0035902//response to immobilization stress;GO:0005975//carbohydrate metabolic process;GO:0030277//maintenance of gastrointestinal epithelium;GO:0008285//negative regulation of cell proliferation","K01176//alpha-amylase [EC:3.2.1.1];K05641//ATP-binding cassette, subfamily A (ABC1), member 1","XP_003280716.1//PREDICTED: trefoil factor 1 [Nomascus leucogenys]","2//1"]
[7133,3682,0.37,0.5,0.434402824145775,0.498881195771976,"*",0.345694,"TNFRSF1B","GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0043025//neuronal cell body;GO:0043196//varicosity;GO:0005887//integral component of plasma membrane;GO:0045121//membrane raft;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0035579//specific granule membrane;GO:0005886//plasma membrane","GO:0031625//ubiquitin protein ligase binding;GO:0005031//tumor necrosis factor-activated receptor activity","GO:0050779//RNA destabilization;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0097191//extrinsic apoptotic signaling pathway;GO:0097190//apoptotic signaling pathway;GO:0042127//regulation of cell proliferation;GO:0051044//positive regulation of membrane protein ectodomain proteolysis;GO:0071222//cellular response to lipopolysaccharide;GO:0050728//negative regulation of inflammatory response;GO:0006954//inflammatory response;GO:0007568//aging;GO:0071363//cellular response to growth factor stimulus;GO:0007275//multicellular organism development;GO:0043312//neutrophil degranulation;GO:0006955//immune response;GO:0033209//tumor necrosis factor-mediated signaling pathway","K05141//tumor necrosis factor receptor superfamily member 1B","NP_001057.1//tumor necrosis factor receptor superfamily member 1B precursor [Homo sapiens]","2//1"]
[3111,3485,0.37,0.5,0.434402824145775,0.570554698741162,"*",0.414254,"HLA-DOA","GO:0005765//lysosomal membrane;GO:0010008//endosome membrane;GO:0042613//MHC class II protein complex;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0032395//MHC class II receptor activity;GO:0023026//MHC class II protein complex binding","GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0006955//immune response;GO:0045580//regulation of T cell differentiation;GO:0002587//negative regulation of antigen processing and presentation of peptide antigen via MHC class II","K06752//major histocompatibility complex, class II","NP_002110.1//HLA class II histocompatibility antigen, DO alpha chain precursor [Homo sapiens]","3//A2MP1"]
[2131,3376,19.87,26.85,0.434330215623105,{"v":1.77237958560976E-10,"d":"1.77E-10"},"*",{"v":1.819646e-11,"d":"1.82E-11"},"EXT1","GO:0005783//endoplasmic reticulum;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0000139//Golgi membrane","GO:0008375//acetylglucosaminyltransferase activity;GO:0046872//metal ion binding;GO:0042328//heparan sulfate N-acetylglucosaminyltransferase activity;GO:0016757//transferase activity, transferring glycosyl groups;GO:0046982//protein heterodimerization activity;GO:0015020//glucuronosyltransferase activity;GO:0050508//glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity;GO:0042803//protein homodimerization activity;GO:0050509//N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity","GO:0007498//mesoderm development;GO:0007369//gastrulation;GO:0007492//endoderm development;GO:0006486//protein glycosylation;GO:0007165//signal transduction;GO:0015014//heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process;GO:0001503//ossification;GO:0021772//olfactory bulb development;GO:0006024//glycosaminoglycan biosynthetic process;GO:0072498//embryonic skeletal joint development;GO:0033692//cellular polysaccharide biosynthetic process;GO:0015012//heparan sulfate proteoglycan biosynthetic process;GO:0001501//skeletal system development;GO:0007411//axon guidance","K02366//glucuronyl/N-acetylglucosaminyl transferase EXT1 [EC:2.4.1.224 2.4.1.225]","NP_000118.2//exostosin-1 [Homo sapiens]","2//1"]
[29115,2759,21.58,29.16,0.43429585483892,{"v":4.90012710791367E-9,"d":"4.90E-09"},"*",{"v":5.96948e-10,"d":"5.97E-10"},"SAP30BP","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0045111//intermediate filament cytoskeleton","NA","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0010942//positive regulation of cell death;GO:0006915//apoptotic process","K19607//X-linked retinitis pigmentosa GTPase regulator","NP_001288784.1//SAP30-binding protein isoform 1 [Homo sapiens];XP_012893425.1//PREDICTED: SAP30-binding protein [Dipodomys ordii]","1//3;7"]
[4696,414,181.96,245.85,0.434157015416323,{"v":1.68946886018349e-10,"d":"1.69E-10"},"*",{"v":1.729236e-11,"d":"1.73E-11"},"NDUFA3","GO:0005747//mitochondrial respiratory chain complex I;GO:0016021//integral component of membrane","NA","NA","K03947//NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 3","XP_010378998.1//PREDICTED: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 isoform X2 [Rhinopithecus roxellana]","3//A2MP1"]
[10516,2637,0.94,1.27,0.434095835094529,0.329438886932944,"*",0.1977582,"FBLN5","GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0071953//elastic fiber;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix","GO:0008022//protein C-terminus binding;GO:0005178//integrin binding;GO:0005509//calcium ion binding;GO:0042803//protein homodimerization activity","GO:0001558//regulation of cell growth;GO:0007160//cell-matrix adhesion;GO:2000121//regulation of removal of superoxide radicals;GO:0030198//extracellular matrix organization;GO:0048251//elastic fiber assembly;GO:0046903//secretion;GO:0034394//protein localization to cell surface","K17340//fibulin 5","EHH28115.1//hypothetical protein EGK_18468, partial [Macaca mulatta]","3//A2MP1"]
[23746,2801,0.97,1.31,0.433510159350323,0.358990868362157,"*",0.220914,"AIPL1","GO:0005634//nucleus;GO:0001917//photoreceptor inner segment;GO:0005737//cytoplasm","GO:0001918//farnesylated protein binding;GO:0051082//unfolded protein binding","GO:0007603//phototransduction, visible light;GO:0001895//retina homeostasis;GO:0007601//visual perception;GO:0043066//negative regulation of apoptotic process;GO:0030823//regulation of cGMP metabolic process;GO:0018343//protein farnesylation","K17767//AH receptor-interacting protein","XP_011850056.1//PREDICTED: aryl-hydrocarbon-interacting protein-like 1 isoform X6 [Mandrillus leucophaeus];NP_001028226.1//aryl-hydrocarbon-interacting protein-like 1 isoform 2 [Homo sapiens];NP_001272329.1//aryl-hydrocarbon-interacting protein-like 1 isoform 5 [Homo sapiens];NP_001272328.1//aryl-hydrocarbon-interacting protein-like 1 isoform 4 [Homo sapiens];NP_001028227.1//aryl-hydrocarbon-interacting protein-like 1 isoform 3 [Homo sapiens];NP_055151.3//aryl-hydrocarbon-interacting protein-like 1 isoform 1 [Homo sapiens];NP_001272330.1//aryl-hydrocarbon-interacting protein-like 1 isoform 6 [Homo sapiens]","4;1//3;2//1"]
[79639,2287,7.37,9.95,0.433031906335941,0.00149113697231834,"*",0.00043164,"TMEM53","GO:0005634//nucleus;GO:0016021//integral component of membrane","NA","NA","K09131//uncharacterized protein;K04460//serine/threonine-protein phosphatase 5 [EC:3.1.3.16]","NP_078863.2//transmembrane protein 53 isoform 1 [Homo sapiens];XP_021573086.1//transmembrane protein 53 isoform X3 [Carlito syrichta];XP_021573085.1//transmembrane protein 53 isoform X2 [Carlito syrichta];XP_008065852.2//transmembrane protein 53 isoform X1 [Carlito syrichta]","1//3;3//A2MP1"]
[92129,1206,0.2,0.27,0.432959407276106,0.811521767461431,"*",0.724446,"RIPPLY1","GO:0005634//nucleus","NA","GO:0045892//negative regulation of transcription, DNA-templated;GO:0032525//somite rostral/caudal axis specification;GO:0060349//bone morphogenesis;GO:0006351//transcription, DNA-templated;GO:0001757//somite specification;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0009880//embryonic pattern specification;GO:0007219//Notch signaling pathway","NA","NP_612391.1//protein ripply1 isoform 1 [Homo sapiens];XP_012666825.1//PREDICTED: protein ripply1 isoform X2 [Otolemur garnettii]","1//3;2//1"]
[8284,5551,0.2,0.27,0.432959407276106,0.542710781315605,"*",0.388398,"KDM5D","GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0046872//metal ion binding;GO:0032453//histone demethylase activity (H3-K4 specific);GO:0003677//DNA binding;GO:0050681//androgen receptor binding;GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;GO:0032452//histone demethylase activity","GO:0002457//T cell antigen processing and presentation;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0034720//histone H3-K4 demethylation;GO:0060765//regulation of androgen receptor signaling pathway","K11446//histone demethylase JARID1 [EC:1.14.11.-]","NP_001140177.1//lysine-specific demethylase 5D isoform 1 [Homo sapiens];NP_001140178.1//lysine-specific demethylase 5D isoform 3 [Homo sapiens];NP_004644.2//lysine-specific demethylase 5D isoform 2 [Homo sapiens]","1//3;4"]
[3310,2370,0.2,0.27,0.432959407276106,0.71835472478429,"*",0.60458,"HSPA6","GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome;GO:0072562//blood microparticle;GO:0005737//cytoplasm;GO:0005814//centriole;GO:0005829//cytosol;GO:0005576//extracellular region;GO:1904813//ficolin-1-rich granule lumen","GO:0005524//ATP binding;GO:0051082//unfolded protein binding;GO:0031072//heat shock protein binding;GO:0019899//enzyme binding;GO:0042623//ATPase activity, coupled","GO:0006986//response to unfolded protein;GO:0043312//neutrophil degranulation;GO:0042026//protein refolding;GO:0034605//cellular response to heat","K03283//heat shock 70kDa protein 1/2/6/8","NP_002146.2//heat shock 70 kDa protein 6 [Homo sapiens]",4]
[126003,714,39.52,53.29,0.431281886175357,{"v":1.59815805432407e-05,"d":"1.60E-05"},"*",{"v":3.20452e-06,"d":"3.20E-06"},"TRAPPC5","NA","NA","NA","K20280//trafficking protein particle complex subunit 5","XP_017735450.1//PREDICTED: trafficking protein particle complex subunit 5 [Rhinopithecus bieti];OWK11881.1//TRAPPC5 [Cervus elaphus hippelaphus];XP_002761715.2//PREDICTED: trafficking protein particle complex subunit 5 isoform X1 [Callithrix jacchus]","1//3;2//1"]
[51282,961,46.73,63.01,0.431231772450063,{"v":1.09792396439791E-6,"d":"1.10E-06"},"*",{"v":1.837892e-07,"d":"1.84E-07"},"SCAND1","GO:0005634//nucleus","GO:0003723//RNA binding;GO:0003677//DNA binding;GO:0042802//identical protein binding;GO:0003700//DNA binding transcription factor activity","GO:0006355//regulation of transcription, DNA-templated;GO:0042127//regulation of cell proliferation;GO:0030851//granulocyte differentiation;GO:0006915//apoptotic process","K09229//KRAB and SCAN domains-containing zinc finger protein;K09230//SCAN domain-containing zinc finger protein","NP_361012.2//SCAN domain-containing protein 1 isoform 2 [Homo sapiens];AAF66832.1//SCAN-related protein RAZ1, partial [Homo sapiens]","3//A2MP1;2//1"]
[91179,3499,0.89,1.2,0.431157164642121,0.253410604242156,"*",0.1436004,"SCARF2","GO:0005925//focal adhesion;GO:0016021//integral component of membrane","NA","GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules","K06776//receptor-type tyrosine-protein phosphatase kappa [EC:3.1.3.48];K02258//cytochrome c oxidase assembly protein subunit 11","XP_007973174.1//PREDICTED: scavenger receptor class F member 2 isoform X1 [Chlorocebus sabaeus];XP_007973175.1//PREDICTED: scavenger receptor class F member 2 isoform X2 [Chlorocebus sabaeus]","6;4"]
[8733,2105,84.41,113.76,0.43050754071919,{"v":1.32486497861163E-25,"d":"1.32E-25"},"*",{"v":4.42064e-27,"d":"4.42E-27"},"GPAA1","GO:0016020//membrane;GO:0042765//GPI-anchor transamidase complex;GO:0005789//endoplasmic reticulum membrane","GO:0015631//tubulin binding;GO:0034235//GPI anchor binding","GO:0016255//attachment of GPI anchor to protein;GO:0006461//protein complex assembly;GO:0006621//protein retention in ER lumen","K05289//glycosylphosphatidylinositol transamidase","NP_003792.1//glycosylphosphatidylinositol anchor attachment 1 protein [Homo sapiens]","3//A2MP1"]
[93185,2269,9.24,12.45,0.430180985539386,0.000665112884825986,"*",0.0001794564,"IGSF8","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","NA","GO:0007399//nervous system development;GO:0006928//movement of cell or subcellular component;GO:0008283//cell proliferation;GO:0007338//single fertilization;GO:0007519//skeletal muscle tissue development","K06730//immunoglobulin superfamily, member 8","XP_012517371.1//PREDICTED: immunoglobulin superfamily member 8 isoform X1 [Propithecus coquereli];NP_443100.1//immunoglobulin superfamily member 8 precursor [Homo sapiens]","1//3;2//1;5"]
[4261,3899,0.72,0.97,0.429987840744815,0.23914880652514,"*",0.1339916,"CIITA","GO:0016605//PML body;GO:0005654//nucleoplasm","GO:0016746//transferase activity, transferring acyl groups;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0044212//transcription regulatory region DNA binding;GO:0008022//protein C-terminus binding;GO:0003713//transcription coactivator activity;GO:0005525//GTP binding;GO:0033613//activating transcription factor binding;GO:0032403//protein complex binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0032966//negative regulation of collagen biosynthetic process;GO:0006351//transcription, DNA-templated;GO:0045345//positive regulation of MHC class I biosynthetic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0046677//response to antibiotic;GO:0034341//response to interferon-gamma;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006955//immune response;GO:0045348//positive regulation of MHC class II biosynthetic process","K08060//class II, major histocompatibility complex, transactivator","XP_011885897.1//PREDICTED: MHC class II transactivator isoform X8 [Cercocebus atys];NP_001273332.1//MHC class II transactivator isoform 3 [Homo sapiens];XP_011885893.1//PREDICTED: MHC class II transactivator isoform X6 [Cercocebus atys]","1//3;3//A2MP1"]
[60598,2550,0.72,0.97,0.429987840744815,0.422196959603659,"*",0.277412,"KCNK15","GO:0005887//integral component of plasma membrane","GO:0022841//potassium ion leak channel activity","GO:0030322//stabilization of membrane potential;GO:0071805//potassium ion transmembrane transport","K04923//potassium channel subfamily K member 15","EAW75900.1//potassium channel, subfamily K, member 15 [Homo sapiens]","3//A2MP1"]
[79033,1365,64.7,87.16,0.429900484236037,{"v":2.39358092488013e-09,"d":"2.39E-09"},"*",{"v":2.81254e-10,"d":"2.81E-10"},"ERI3","NA","GO:0003723//RNA binding;GO:0046872//metal ion binding;GO:0004527//exonuclease activity;GO:0003676//nucleic acid binding","GO:0006259//DNA metabolic process","K18418//ERI1 exoribonuclease 3 [EC:3.1.-.-]","XP_018872689.1//PREDICTED: ERI1 exoribonuclease 3 isoform X4 [Gorilla gorilla gorilla];XP_017396243.1//PREDICTED: ERI1 exoribonuclease 3 isoform X6 [Cebus capucinus imitator];XP_011801358.1//PREDICTED: ERI1 exoribonuclease 3 isoform X5 [Colobus angolensis palliatus];AAC19158.1//unknown, partial [Homo sapiens]","1//3;2//1"]
[11221,2680,1.7,2.29,0.429812851959242,0.161100027527406,"*",0.082799,"DUSP10","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0005737//cytoplasm","GO:0017017//MAP kinase tyrosine/serine/threonine phosphatase activity;GO:0004721//phosphoprotein phosphatase activity;GO:0008432//JUN kinase binding;GO:0004725//protein tyrosine phosphatase activity;GO:0016791//phosphatase activity;GO:0048273//mitogen-activated protein kinase p38 binding;GO:0033549//MAP kinase phosphatase activity","GO:0032496//response to lipopolysaccharide;GO:0010633//negative regulation of epithelial cell migration;GO:0000188//inactivation of MAPK activity;GO:0043508//negative regulation of JUN kinase activity;GO:0035970//peptidyl-threonine dephosphorylation;GO:0046329//negative regulation of JNK cascade;GO:0006470//protein dephosphorylation;GO:0060266//negative regulation of respiratory burst involved in inflammatory response;GO:0016311//dephosphorylation;GO:0045591//positive regulation of regulatory T cell differentiation;GO:1905042//negative regulation of epithelium regeneration;GO:0048709//oligodendrocyte differentiation;GO:0030336//negative regulation of cell migration;GO:0048715//negative regulation of oligodendrocyte differentiation;GO:0002819//regulation of adaptive immune response;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0070303//negative regulation of stress-activated protein kinase signaling cascade;GO:1903753//negative regulation of p38MAPK cascade;GO:0050680//negative regulation of epithelial cell proliferation;GO:1990264//peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity;GO:0044387//negative regulation of protein kinase activity by regulation of protein phosphorylation;GO:0090335//regulation of brown fat cell differentiation","K20216//dual specificity phosphatase 10 [EC:3.1.3.16 3.1.3.48]","NP_009138.1//dual specificity protein phosphatase 10 [Homo sapiens]",5]
[79734,1681,12.68,17.08,0.429753229481083,0.000978166906159015,"*",0.000273414,"KCTD17","GO:0005783//endoplasmic reticulum;GO:0005737//cytoplasm;GO:0031463//Cul3-RING ubiquitin ligase complex","GO:0042802//identical protein binding;GO:0097602//cullin family protein binding;GO:0032403//protein complex binding","GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0032469//endoplasmic reticulum calcium ion homeostasis;GO:0051260//protein homooligomerization;GO:0030030//cell projection organization;GO:0045724//positive regulation of cilium assembly","K21914//BTB/POZ domain-containing protein KCTD2/5/17","NP_078957.2//BTB/POZ domain-containing protein KCTD17 isoform 2 [Homo sapiens];NP_001269613.1//BTB/POZ domain-containing protein KCTD17 isoform 1 [Homo sapiens];XP_007973876.1//PREDICTED: BTB/POZ domain-containing protein KCTD17 isoform X7 [Chlorocebus sabaeus];XP_017364403.1//PREDICTED: BTB/POZ domain-containing protein KCTD17 isoform X1 [Cebus capucinus imitator]","1//3;3//A2MP1"]
[127002,2553,1.99,2.68,0.429464569914124,0.11818969379562,"*",0.0567642,"ATXN7L2","NA","NA","NA","K11318//ataxin-7","NP_001337104.1//ataxin-7-like protein 2 isoform 1 [Homo sapiens];NP_699171.3//ataxin-7-like protein 2 isoform 2 [Homo sapiens];NP_001337103.1//ataxin-7-like protein 2 isoform 3 [Homo sapiens]","1//3;5"]
[60673,1435,40.02,53.89,0.429296419484005,{"v":3.0478719366558e-08,"d":"3.05E-08"},"*",{"v":4.09652e-09,"d":"4.10E-09"},"ATG101","NA","NA","NA","K19730//autophagy-related protein 101","XP_015998147.1//PREDICTED: autophagy-related protein 101 isoform X1 [Rousettus aegyptiacus]","4;1//3"]
[199990,929,57.53,77.46,0.429137031144108,1.0075306173511E-4,"*",{"v":2.3192e-05,"d":"2.32E-05"},"FAAP20","GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0030054//cell junction;GO:0043240//Fanconi anaemia nuclear complex;GO:0005694//chromosome","GO:0070530//K63-linked polyubiquitin modification-dependent protein binding;GO:0043130//ubiquitin binding;GO:0046872//metal ion binding;GO:0031593//polyubiquitin modification-dependent protein binding;GO:0140036//ubiquitin-dependent protein binding","GO:0019985//translesion synthesis;GO:0036297//interstrand cross-link repair;GO:0006974//cellular response to DNA damage stimulus","K12581//CCR4-NOT transcription complex subunit 7/8;K16628//collagen, type VII, alpha;K06236//collagen, type I, alpha;K18952//atypical protein kinase C zeta type [EC:2.7.11.13];K04460//serine/threonine-protein phosphatase 5 [EC:3.1.3.16]","Q6NZ36.2//RecName: Full=Fanconi anemia core complex-associated protein 20; AltName: Full=FANCA-associated protein of 20 kDa; AltName: Full=Fanconi anemia-associated protein of 20 kDa;NP_001269599.1//Fanconi anemia core complex-associated protein 20 isoform 6 [Homo sapiens];AAH66360.1//C1orf86 protein, partial [Homo sapiens];NP_001139782.1//Fanconi anemia core complex-associated protein 20 isoform 1 [Homo sapiens];BAB70965.1//unnamed protein product [Homo sapiens];NP_001243874.1//Fanconi anemia core complex-associated protein 20 isoform 3 [Homo sapiens];NP_001243875.1//Fanconi anemia core complex-associated protein 20 isoform 4 [Homo sapiens];XP_016807965.1//PREDICTED: Fanconi anemia core complex-associated protein 20 isoform X2 [Pan troglodytes]","1//3;2//1"]
[93233,3234,0.26,0.35,0.428843298803874,0.578831958050374,"*",0.421532,"CCDC114","NA","NA","NA","K19720//collagen, type III, alpha","XP_005259470.1//PREDICTED: coiled-coil domain-containing protein 114 isoform X1 [Homo sapiens]","3//A2MP1"]
[10534,803,31.62,42.55,0.428321764214954,0.000220283945116042,"*",{"v":5.40712e-05,"d":"5.41E-05"},"SSSCA1","NA","NA","NA","K11984//U4/U6.U5 tri-snRNP-associated protein 1","XP_013976486.1//Sjoegren syndrome/scleroderma autoantigen 1 isoform X1 [Canis lupus familiaris];XP_009421753.1//PREDICTED: Sjoegren syndrome/scleroderma autoantigen 1 [Pan troglodytes]","1//3;2//1"]
[8357,473,0.55,0.74,0.42809365210429,0.810214969124134,"*",0.724446,"HIST1H3H","NA","NA","NA","K11253//histone H3","XP_021079072.1//LOW QUALITY PROTEIN: uncharacterized protein LOC101825376 [Mesocricetus auratus]","2//1"]
[9001,3876,0.84,1.13,0.427861539636427,0.265186536419214,"*",0.1520664,"HAP1","GO:0005576//extracellular region","NA","NA","K04647//huntingtin-associated protein 1","XP_004282921.1//PREDICTED: LOW QUALITY PROTEIN: huntingtin-associated protein 1 [Orcinus orca];XP_010384888.1//PREDICTED: LOW QUALITY PROTEIN: huntingtin-associated protein 1 [Rhinopithecus roxellana]","1//3;2//1"]
[10882,1517,27.32,36.75,0.427786766320999,{"v":1.54760526718118e-06,"d":"1.55E-06"},"*",{"v":2.63618e-07,"d":"2.64E-07"},"C1QL1","NA","NA","NA","K06237//collagen, type IV, alpha","XP_020369783.1//LOW QUALITY PROTEIN: uncharacterized protein LOC109914588 [Rhincodon typus]",4]
[11316,1062,78.4,105.46,0.427770342377262,{"v":5.04889487701223E-11,"d":"5.05E-11"},"*",{"v":4.90856e-12,"d":"4.91E-12"},"COPE","GO:0005654//nucleoplasm;GO:0030126//COPI vesicle coat;GO:0030137//COPI-coated vesicle;GO:0000139//Golgi membrane;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0030133//transport vesicle;GO:0005789//endoplasmic reticulum membrane","GO:0005198//structural molecule activity","GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0015031//protein transport;GO:0006891//intra-Golgi vesicle-mediated transport","K17268//coatomer subunit epsilon","NP_955474.1//coatomer subunit epsilon isoform b [Homo sapiens];NP_001317398.1//coatomer subunit epsilon isoform d [Homo sapiens];NP_955476.1//coatomer subunit epsilon isoform c [Homo sapiens];NP_009194.2//coatomer subunit epsilon isoform a [Homo sapiens]","1//3;3//A2MP1"]
[25911,864,10.75,14.46,0.427730892474295,0.0237001669900376,"*",0.00908452,"DPCD","GO:0005634//nucleus","NA","GO:0030317//flagellated sperm motility;GO:0007368//determination of left/right symmetry;GO:0021670//lateral ventricle development;GO:0060972//left/right pattern formation;GO:0007283//spermatogenesis;GO:0021678//third ventricle development;GO:0003351//epithelial cilium movement","K20800//protein DPCD","NP_001316673.1//protein DPCD isoform 4 [Homo sapiens];EAW49754.1//deleted in a mouse model of primary ciliary dyskinesia, isoform CRA_a [Homo sapiens];EAW49755.1//deleted in a mouse model of primary ciliary dyskinesia, isoform CRA_b [Homo sapiens]","1//3;2//1"]
[79091,1617,9.54,12.83,0.427459999084171,5.21278689559165E-3,"*",1.687776E-3,"METTL22","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0043234//protein complex","GO:0016279//protein-lysine N-methyltransferase activity;GO:0031072//heat shock protein binding;GO:0008276//protein methyltransferase activity","GO:0006479//protein methylation","K21804//protein N-lysine methyltransferase METTL21A [EC:2.1.1.-];K21806//protein N-lysine methyltransferase METTL21D [EC:2.1.1.-];K17536//connector enhancer of kinase suppressor of Ras 2","NP_077014.3//methyltransferase-like protein 22 [Homo sapiens]","3//A2MP1"]
[100130519,1930,0.87,1.17,0.427421223734676,0.469185673758865,"*",0.31889,"TMEM221","GO:0016021//integral component of membrane","NA","NA","K14000//ribosome-binding protein 1","NP_001177773.1//transmembrane protein 221 [Homo sapiens]","1//3"]
[705,2005,16.94,22.78,0.427333872375913,{"v":1.50084269559748e-05,"d":"1.50E-05"},"*",{"v":2.98778e-06,"d":"2.99E-06"},"BYSL","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0045177//apical part of cell","GO:0003723//RNA binding","GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0007565//female pregnancy;GO:0007155//cell adhesion;GO:0008283//cell proliferation;GO:0001829//trophectodermal cell differentiation;GO:0006364//rRNA processing","K14797//essential nuclear protein 1","NP_004044.3//bystin [Homo sapiens]","3//A2MP1"]
[59271,1878,30.17,40.57,0.42729860605957,{"v":1.74704387878788E-9,"d":"1.75E-09"},"*",{"v":2.02112E-10,"d":"2.02E-10"},"EVA1C","GO:0005576//extracellular region;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0030246//carbohydrate binding;GO:0008201//heparin binding","NA","K00111//glycerol-3-phosphate dehydrogenase [EC:1.1.5.3];K06236//collagen, type I, alpha;K01099//inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]","NP_001273485.1//protein eva-1 homolog C isoform 2 precursor [Homo sapiens];NP_001307673.1//protein eva-1 homolog C isoform 3 [Homo sapiens];NP_478067.2//protein eva-1 homolog C isoform 1 precursor [Homo sapiens]","4;1//3"]
[7041,1790,25.99,34.93,0.426510008922664,{"v":4.24513193296089e-07,"d":"4.25E-07"},"*",{"v":6.65976e-08,"d":"6.66E-08"},"TGFB1I1","GO:0031012//extracellular matrix;GO:0005856//cytoskeleton;GO:0005925//focal adhesion;GO:0005622//intracellular;GO:0016363//nuclear matrix;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0003713//transcription coactivator activity;GO:0050681//androgen receptor binding;GO:0070411//I-SMAD binding;GO:0048495//Roundabout binding","GO:0045165//cell fate commitment;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0045599//negative regulation of fat cell differentiation;GO:0009408//response to heat;GO:0030521//androgen receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0030579//ubiquitin-dependent SMAD protein catabolic process;GO:0007155//cell adhesion;GO:0016331//morphogenesis of embryonic epithelium;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0016055//Wnt signaling pathway;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0030855//epithelial cell differentiation;GO:0008285//negative regulation of cell proliferation","K05760//paxillin","XP_005591807.1//PREDICTED: transforming growth factor beta-1-induced transcript 1 protein isoform X1 [Macaca fascicularis];XP_007988985.1//PREDICTED: LOW QUALITY PROTEIN: transforming growth factor beta-1-induced transcript 1 protein [Chlorocebus sabaeus];BAA24799.1//Hic-5, partial [Homo sapiens]","1//3;4;2//1"]
[10567,821,156.74,210.47,0.425241206763981,{"v":1.15292082844639E-17,"d":"1.15E-17"},"*",{"v":6.59678E-19,"d":"6.60E-19"},"RABAC1","GO:0016020//membrane;GO:0008021//synaptic vesicle;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0005886//plasma membrane","GO:0008022//protein C-terminus binding;GO:0042802//identical protein binding;GO:0070064//proline-rich region binding","NA","K20359//PRA1 family protein 1","NP_006414.2//prenylated Rab acceptor protein 1 [Homo sapiens]","2//1"]
[643911,841,6.92,9.29,0.424906558745928,0.123283662855665,"*",0.0596738,"CRNDE","NA","NA","NA","NA","NP_001295892.1//colorectal neoplasia differentially expressed peptide [Homo sapiens]","1//3"]
[79751,2667,36.75,49.33,0.424721037383403,{"v":5.25020060876758e-14,"d":"5.25E-14"},"*",{"v":3.97364e-15,"d":"3.97E-15"},"SLC25A22","GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane","GO:0005313//L-glutamate transmembrane transporter activity;GO:0005280//hydrogen:amino acid symporter activity;GO:0005314//high-affinity glutamate transmembrane transporter activity","GO:0055085//transmembrane transport;GO:0015813//L-glutamate transport;GO:0006811//ion transport;GO:0006839//mitochondrial transport","K15107//solute carrier family 25 (mitochondrial glutamate transporter), member 18/22","NP_078974.1//mitochondrial glutamate carrier 1 [Homo sapiens]","1//3;5"]
[6521,4953,0.38,0.51,0.42449782852791,0.499160446210821,"*",0.34595,"SLC4A1","GO:0070062//extracellular exosome;GO:0016323//basolateral plasma membrane;GO:0072562//blood microparticle;GO:0030863//cortical cytoskeleton;GO:0005887//integral component of plasma membrane;GO:0030018//Z disc;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0043495//protein membrane anchor;GO:0015108//chloride transmembrane transporter activity;GO:0005452//inorganic anion exchanger activity;GO:0042803//protein homodimerization activity;GO:0015106//bicarbonate transmembrane transporter activity;GO:0015301//anion:anion antiporter activity;GO:0008510//sodium:bicarbonate symporter activity;GO:0030506//ankyrin binding;GO:0008509//anion transmembrane transporter activity","GO:0015701//bicarbonate transport;GO:0006820//anion transport;GO:0006821//chloride transport;GO:0051453//regulation of intracellular pH;GO:0006873//cellular ion homeostasis","K06573//solute carrier family 4 (anion exchanger), member 1","NP_000333.1//band 3 anion transport protein [Homo sapiens]","3//A2MP1"]
[396,1885,633.73,850.46,0.424375070114444,{"v":8.17586905882353e-153,"d":"8.18E-153"},"*",{"v":2.6103e-155,"d":"2.61E-155"},"ARHGDIA","GO:0070062//extracellular exosome;GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0001772//immunological synapse;GO:0005737//cytoplasm","GO:0005094//Rho GDP-dissociation inhibitor activity;GO:0017048//Rho GTPase binding;GO:0051879//Hsp90 protein binding;GO:0005504//fatty acid binding;GO:0019901//protein kinase binding;GO:0005096//GTPase activator activity","GO:0071260//cellular response to mechanical stimulus;GO:0007162//negative regulation of cell adhesion;GO:0071407//cellular response to organic cyclic compound;GO:0043066//negative regulation of apoptotic process;GO:0050772//positive regulation of axonogenesis;GO:0030336//negative regulation of cell migration;GO:0008360//regulation of cell shape;GO:2000249//regulation of actin cytoskeleton reorganization;GO:0006928//movement of cell or subcellular component;GO:0007266//Rho protein signal transduction;GO:0032880//regulation of protein localization;GO:0050771//negative regulation of axonogenesis;GO:0035023//regulation of Rho protein signal transduction;GO:0071526//semaphorin-plexin signaling pathway;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0071461//cellular response to redox state","K12462//Rho GDP-dissociation inhibitor","NP_001288172.1//rho GDP-dissociation inhibitor 1 isoform e [Homo sapiens];NP_001288169.1//rho GDP-dissociation inhibitor 1 isoform c [Homo sapiens];XP_003931694.2//PREDICTED: rho GDP-dissociation inhibitor 1 isoform X1 [Saimiri boliviensis boliviensis];NP_001288171.1//rho GDP-dissociation inhibitor 1 isoform d [Homo sapiens]","1//3;2//1;5"]
[92610,3090,1.96,2.63,0.424209145177094,0.106186646088571,"*",0.0501352,"TIFA","GO:0005622//intracellular","NA","GO:0007249//I-kappaB kinase/NF-kappaB signaling","NA","XP_003899151.2//TRAF-interacting protein with FHA domain-containing protein A isoform X1 [Papio anubis]","2//1"]
[9253,3520,36.44,48.89,0.424016446206087,{"v":6.19574181291759e-18,"d":"6.20E-18"},"*",{"v":3.48302e-19,"d":"3.48E-19"},"NUMBL","GO:0005737//cytoplasm","NA","GO:0007399//nervous system development;GO:0021670//lateral ventricle development;GO:0007409//axonogenesis;GO:0034332//adherens junction organization;GO:0050769//positive regulation of neurogenesis;GO:0019538//protein metabolic process;GO:0021849//neuroblast division in subventricular zone;GO:0019221//cytokine-mediated signaling pathway","K06057//numb","NP_004747.1//numb-like protein isoform a [Homo sapiens];XP_004874284.1//numb-like protein isoform X3 [Heterocephalus glaber]","4;1//3;2//1"]
[23770,1810,102.88,138,0.423705719224946,{"v":8.20863925e-26,"d":"8.21E-26"},"*",{"v":2.71326e-27,"d":"2.71E-27"},"FKBP8","GO:0005740//mitochondrial envelope;GO:0043234//protein complex;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016021//integral component of membrane","GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0042802//identical protein binding;GO:0097718//disordered domain specific binding","GO:0043010//camera-type eye development;GO:0021904//dorsal/ventral neural tube patterning;GO:0030513//positive regulation of BMP signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0035264//multicellular organism growth;GO:0001933//negative regulation of protein phosphorylation;GO:0001708//cell fate specification;GO:0007224//smoothened signaling pathway","K09574//FK506-binding protein 8 [EC:5.2.1.8]","XP_002912777.1//PREDICTED: peptidyl-prolyl cis-trans isomerase FKBP8 isoform X3 [Ailuropoda melanoleuca];XP_006876371.1//PREDICTED: peptidyl-prolyl cis-trans isomerase FKBP8 isoform X2 [Chrysochloris asiatica]","4;1//3"]
[5003,1916,4.75,6.37,0.42336585903799,0.0530765644783118,"*",0.022674,"SLC22A18AS","NA","NA","NA","K08214//MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 18","NP_009036.2//beckwith-Wiedemann syndrome chromosomal region 1 candidate gene B protein isoform a [Homo sapiens];XP_011785497.1//PREDICTED: LOW QUALITY PROTEIN: beckwith-Wiedemann syndrome chromosomal region 1 candidate gene B protein [Colobus angolensis palliatus]","1//3;3//A2MP1"]
[6723,1273,148.83,199.53,0.422940313695785,{"v":7.08526160305344e-26,"d":"7.09E-26"},"*",{"v":2.3242e-27,"d":"2.32E-27"},"SRM","NA","GO:0004766//spermidine synthase activity;GO:0016740//transferase activity;GO:0042803//protein homodimerization activity","GO:1990830//cellular response to leukemia inhibitory factor;GO:0008295//spermidine biosynthetic process;GO:0006596//polyamine biosynthetic process","K00797//spermidine synthase [EC:2.5.1.16]","XP_016809435.1//PREDICTED: spermidine synthase [Pan troglodytes]","2//1"]
[391,1332,71.67,96.06,0.422566454059925,{"v":1.84105606292135e-13,"d":"1.84E-13"},"*",{"v":1.436056e-14,"d":"1.44E-14"},"RHOG","NA","NA","NA","K07863//Ras homolog gene family, member G","XP_011900460.1//PREDICTED: rho-related GTP-binding protein RhoG isoform X1 [Cercocebus atys]","3//A2MP1"]
[6609,2482,6.82,9.14,0.422422426033897,0.00360190241678322,"*",0.001128554,"SMPD1","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005764//lysosome;GO:0005768//endosome;GO:0042599//lamellar body;GO:0043202//lysosomal lumen;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0046872//metal ion binding;GO:0061750//acid sphingomyelin phosphodiesterase activity;GO:0004767//sphingomyelin phosphodiesterase activity;GO:0008270//zinc ion binding;GO:0016798//hydrolase activity, acting on glycosyl bonds","GO:0006685//sphingomyelin catabolic process;GO:0007399//nervous system development;GO:0042493//response to drug;GO:0007165//signal transduction;GO:0043407//negative regulation of MAP kinase activity;GO:0035307//positive regulation of protein dephosphorylation;GO:0006687//glycosphingolipid metabolic process;GO:0023021//termination of signal transduction;GO:0043065//positive regulation of apoptotic process;GO:0042220//response to cocaine;GO:0006684//sphingomyelin metabolic process;GO:0046513//ceramide biosynthetic process","K12350//sphingomyelin phosphodiesterase [EC:3.1.4.12]","BAD93012.1//sphingomyelin phosphodiesterase 1, acid lysosomal isoform 1 precursor variant, partial [Homo sapiens];ADW09002.1//sphingomyelin phosphodiesterase 1 precursor isoform 7 [Homo sapiens]","4;1//3;2//1"]
[1375,2750,9.83,13.17,0.421992023915934,0.000322261448098765,"*",{"v":8.17052e-05,"d":"8.17E-05"},"CPT1B","GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane","GO:0016746//transferase activity, transferring acyl groups;GO:0004095//carnitine O-palmitoyltransferase activity","GO:0015909//long-chain fatty acid transport;GO:0006635//fatty acid beta-oxidation;GO:0006853//carnitine shuttle","K19523//carnitine O-palmitoyltransferase 1, muscle isoform [EC:2.3.1.21]","NP_001138606.1//carnitine O-palmitoyltransferase 1, muscle isoform isoform c [Homo sapiens];NP_004368.1//carnitine O-palmitoyltransferase 1, muscle isoform isoform a [Homo sapiens]","1//3;3//A2MP1;2//1"]
[3106,1624,9.83,13.16,0.420896167394661,0.00517052637415361,"*",1.673122E-3,"HLA-B","NA","NA","NA","K06751//major histocompatibility complex, class I","CEF48040.1//HLA class I antigen [Homo sapiens]",7]
[55507,1038,0.71,0.95,0.420108488826266,0.641531123765432,"*",0.520486,"GPRC5D","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004930//G-protein coupled receptor activity","NA","K04621//G protein-coupled receptor family C group 5 member D","NP_061124.1//G-protein coupled receptor family C group 5 member D [Homo sapiens]","1//3"]
[58485,782,319.09,426.69,0.419224903087494,{"v":6.43703049230769e-32,"d":"6.44E-32"},"*",{"v":1.623966e-33,"d":"1.62E-33"},"TRAPPC1","GO:0005783//endoplasmic reticulum;GO:0005737//cytoplasm;GO:0030008//TRAPP complex;GO:0000139//Golgi membrane;GO:0035578//azurophil granule lumen;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005576//extracellular region","GO:0017112//Rab guanyl-nucleotide exchange factor activity","GO:0006810//transport;GO:0043312//neutrophil degranulation;GO:0048208//COPII vesicle coating;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0061024//membrane organization","K20300//trafficking protein particle complex subunit 1","XP_005067617.2//trafficking protein particle complex subunit 1 [Mesocricetus auratus]","1//3;4"]
[388112,1999,2.32,3.1,0.418143410146666,0.161119652332805,"*",0.082799,"NANOGP8","NA","NA","NA","K10164//homeobox protein Nanog","NP_001342210.1//putative homeobox protein NANOGP8 [Homo sapiens]","1//3"]
[56928,3779,7.29,9.73,0.416520990454175,1.45650478717814E-4,"*",{"v":3.4703e-05,"d":"3.47E-05"},"SPPL2B","GO:0016020//membrane;GO:0005765//lysosomal membrane;GO:0010008//endosome membrane;GO:0005654//nucleoplasm;GO:0005813//centrosome;GO:0030660//Golgi-associated vesicle membrane;GO:0000139//Golgi membrane;GO:0071458//integral component of cytoplasmic side of endoplasmic reticulum membrane;GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0015629//actin cytoskeleton;GO:0005886//plasma membrane","GO:0042803//protein homodimerization activity;GO:0042500//aspartic endopeptidase activity, intramembrane cleaving","GO:0006509//membrane protein ectodomain proteolysis;GO:0033619//membrane protein proteolysis;GO:0031293//membrane protein intracellular domain proteolysis;GO:0010803//regulation of tumor necrosis factor-mediated signaling pathway;GO:0050776//regulation of immune response","K09597//signal peptide peptidase-like 2B [EC:3.4.23.-]","XP_011526440.1//PREDICTED: signal peptide peptidase-like 2B isoform X1 [Homo sapiens]","1//3;2//1"]
[84518,543,26.63,35.51,0.415172931810357,0.0123863015802469,"*",4.39654E-3,"CNFN","NA","NA","NA","NA","EAW57134.1//cornifelin [Homo sapiens]","3//A2MP1"]
[2044,8369,0.06,0.08,0.415037499278844,0.447430099346405,"*",0.299986,"EPHA5","GO:0030425//dendrite;GO:0030424//axon;GO:0009897//external side of plasma membrane;GO:0005791//rough endoplasmic reticulum;GO:0005912//adherens junction;GO:0048471//perinuclear region of cytoplasm;GO:0043025//neuronal cell body;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane","GO:0005004//GPI-linked ephrin receptor activity;GO:0005524//ATP binding;GO:0005003//ephrin receptor activity;GO:0005005//transmembrane-ephrin receptor activity","GO:1904322//cellular response to forskolin;GO:0021766//hippocampus development;GO:0048013//ephrin receptor signaling pathway;GO:0032956//regulation of actin cytoskeleton organization;GO:0048666//neuron development;GO:0019933//cAMP-mediated signaling;GO:0043087//regulation of GTPase activity;GO:0032793//positive regulation of CREB transcription factor activity;GO:0061178//regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0071372//cellular response to follicle-stimulating hormone stimulus;GO:0007411//axon guidance","K05106//Eph receptor A5 [EC:2.7.10.1]","NP_001268695.1//ephrin type-A receptor 5 isoform d [Homo sapiens];NP_004430.4//ephrin type-A receptor 5 isoform a [Homo sapiens];BAD92612.1//ephrin receptor EphA5 isoform a variant, partial [Homo sapiens];NP_001268694.1//ephrin type-A receptor 5 isoform c [Homo sapiens];NP_872272.2//ephrin type-A receptor 5 isoform b [Homo sapiens]","1//3;4;7;2//1"]
[57477,9571,0.06,0.08,0.415037499278844,0.634527201728149,"*",0.4781,"SHROOM4","GO:0016324//apical plasma membrane;GO:0016460//myosin II complex;GO:0005737//cytoplasm;GO:0009925//basal plasma membrane;GO:0030864//cortical actin cytoskeleton;GO:0001725//stress fiber;GO:0009898//cytoplasmic side of plasma membrane;GO:0031941//filamentous actin","GO:0051015//actin filament binding","GO:0050890//cognition;GO:0007015//actin filament organization;GO:0030036//actin cytoskeleton organization;GO:0007420//brain development","K18625//protein Shroom","NP_065768.2//protein Shroom4 [Homo sapiens]","3//A2MP1"]
[8529,2406,0.03,0.04,0.415037499278844,0.646568024008435,"*",0.499032,"CYP4F2","NA","NA","NA","K17729//cytochrome P450 family 4 subfamily F polypeptide 11 [EC:1.14.14.1 1.14.13.194];K17726//leukotriene-B4 20-monooxygenase / phylloquinone omega-hydroxylase [EC:1.14.13.30 1.14.13.194]","XP_004060261.2//PREDICTED: phylloquinone omega-hydroxylase CYP4F2 [Gorilla gorilla gorilla]",4]
[92241,4116,0.03,0.04,0.415037499278844,0.732824878752207,"*",0.623548,"RCSD1","NA","NA","NA","K18615//CapZ-interacting protein","NP_001309852.1//capZ-interacting protein isoform 2 [Homo sapiens];CAB70910.1//hypothetical protein, partial [Homo sapiens]","1//3;3//A2MP1"]
[364,1595,0.39,0.52,0.415037499278844,0.718461606903735,"*",0.60458,"AQP7","GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0015250//water channel activity;GO:0015254//glycerol channel activity;GO:0005215//transporter activity","GO:0006833//water transport;GO:0006091//generation of precursor metabolites and energy;GO:0007588//excretion;GO:0015793//glycerol transport","K08771//aquaporin-7","NP_001305086.1//aquaporin-7 isoform 3 [Homo sapiens];NP_001305087.1//aquaporin-7 isoform 4 [Homo sapiens];XP_021783134.1//aquaporin-7 isoform X2 [Papio anubis];XP_016816209.1//PREDICTED: aquaporin-7 isoform X1 [Pan troglodytes]","1//3;2//1"]
[285367,1233,44.85,59.75,0.41383072794885,{"v":1.01274317996988e-06,"d":"1.01E-06"},"*",{"v":1.68389e-07,"d":"1.68E-07"},"RPUSD3","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0003723//RNA binding;GO:0009982//pseudouridine synthase activity","GO:0006397//mRNA processing;GO:0031119//tRNA pseudouridine synthesis;GO:0001522//pseudouridine synthesis","K01855//tRNA pseudouridine38/39 synthase [EC:5.4.99.45];K05741//diaphanous 2","NP_001136019.1//RNA pseudouridylate synthase domain-containing protein 3 isoform 2 [Homo sapiens];NP_001338665.1//RNA pseudouridylate synthase domain-containing protein 3 isoform 3 [Homo sapiens];NP_775930.2//RNA pseudouridylate synthase domain-containing protein 3 isoform 1 [Homo sapiens];NP_001338667.1//RNA pseudouridylate synthase domain-containing protein 3 isoform 5 [Homo sapiens];NP_001338666.1//RNA pseudouridylate synthase domain-containing protein 3 isoform 4 [Homo sapiens]","4;1//3;2//1"]
[8362,354,1.54,2.05,0.412693558810544,0.718515059891377,"*",0.60458,"HIST1H4K","NA","NA","NA","K11253//histone H3;K11254//histone H4","ELV13502.1//Histone H2B type 1-M [Tupaia chinensis]","2//1"]
[59352,3345,0.76,1.01,0.410283969308209,0.345382536524969,"*",0.209556,"LGR6","GO:0032588//trans-Golgi network membrane;GO:0005887//integral component of plasma membrane;GO:0031982//vesicle;GO:0005886//plasma membrane","GO:0004888//transmembrane signaling receptor activity","GO:0030177//positive regulation of Wnt signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway;GO:0030335//positive regulation of cell migration;GO:0016055//Wnt signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1990523//bone regeneration","K08399//leucine-rich repeat-containing G protein-coupled receptor 6","NP_001017404.1//leucine-rich repeat-containing G-protein coupled receptor 6 isoform 3 [Homo sapiens];NP_001017403.1//leucine-rich repeat-containing G-protein coupled receptor 6 isoform 1 precursor [Homo sapiens];NP_067649.2//leucine-rich repeat-containing G-protein coupled receptor 6 isoform 2 [Homo sapiens]","1//3;2//1"]
[29780,1891,18.79,24.96,0.409652867442193,1.97769697147263E-4,"*",{"v":4.81734e-05,"d":"4.82E-05"},"PARVB","GO:0005856//cytoskeleton;GO:0030018//Z disc;GO:0005925//focal adhesion;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0030027//lamellipodium","GO:0003779//actin binding","GO:0030032//lamellipodium assembly;GO:0071963//establishment or maintenance of cell polarity regulating cell shape;GO:0007155//cell adhesion;GO:0031532//actin cytoskeleton reorganization;GO:0030031//cell projection assembly","K06275//parvin","XP_016884281.1//PREDICTED: beta-parvin isoform X1 [Homo sapiens];AAH46103.2//Parvin, beta [Homo sapiens];NP_001003828.1//beta-parvin isoform a [Homo sapiens];XP_016794838.1//PREDICTED: beta-parvin isoform X2 [Pan troglodytes]","1//3;4;2//1"]
[6626,1646,144.52,191.76,0.408032654216689,{"v":2.97911764361949e-30,"d":"2.98E-30"},"*",{"v":8.03806e-32,"d":"8.04E-32"},"SNRPA","GO:0005685//U1 snRNP;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0019013//viral nucleocapsid","GO:0003723//RNA binding;GO:0030619//U1 snRNA binding;GO:0042802//identical protein binding;GO:1990446//U1 snRNP binding;GO:0035614//snRNA stem-loop binding","GO:0000398//mRNA splicing, via spliceosome;GO:1900363//regulation of mRNA polyadenylation","K11091//U1 small nuclear ribonucleoprotein A","NP_004587.1//U1 small nuclear ribonucleoprotein A [Homo sapiens]",4]
[84628,4806,0.83,1.1,0.406320282177735,0.241967397259664,"*",0.1359798,"NTNG2","NA","NA","NA","K16359//netrin-G2","XP_004375836.1//PREDICTED: netrin-G2 [Trichechus manatus latirostris]","3//A2MP1"]
[6142,671,1057.43,1401.28,0.406183097375507,{"v":1.802314472E-84,"d":"1.80E-84"},"*",{"v":1.353936E-86,"d":"1.35E-86"},"RPL18A","GO:0005840//ribosome;GO:0016020//membrane;GO:0005829//cytosol;GO:0022625//cytosolic large ribosomal subunit","GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome","GO:0006413//translational initiation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0097327//response to antineoplastic agent;GO:0019083//viral transcription;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006412//translation;GO:0006364//rRNA processing","K02882//large subunit ribosomal protein L18Ae","XP_003923253.1//PREDICTED: 60S ribosomal protein L18a [Saimiri boliviensis boliviensis]","3//A2MP1"]
[6916,2385,3.24,4.29,0.404983834614921,0.0709350081759233,"*",0.031502,"TBXAS1","GO:0005623//cell;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0020037//heme binding;GO:0036134//12-hydroxyheptadecatrienoic acid synthase activity;GO:0005506//iron ion binding;GO:0004497//monooxygenase activity;GO:0004796//thromboxane-A synthase activity","GO:0019371//cyclooxygenase pathway;GO:0030644//cellular chloride ion homeostasis;GO:0045907//positive regulation of vasoconstriction;GO:0070542//response to fatty acid;GO:0006690//icosanoid metabolic process;GO:0045471//response to ethanol","K01832//thromboxane-A synthase [EC:5.3.99.5]","NP_001300957.1//thromboxane-A synthase isoform 5 [Homo sapiens];XP_003929807.1//PREDICTED: thromboxane-A synthase [Saimiri boliviensis boliviensis];NP_001124438.1//thromboxane-A synthase isoform 1 [Homo sapiens];NP_001159725.1//thromboxane-A synthase isoform 3 [Homo sapiens]","4;1//3;3//A2MP1;2//1"]
[2867,2069,0.65,0.86,0.403896941673643,0.486458514827995,"*",0.333736,"FFAR2","GO:0042995//cell projection;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0008289//lipid binding;GO:0004930//G-protein coupled receptor activity","GO:0002232//leukocyte chemotaxis involved in inflammatory response;GO:0007186//G-protein coupled receptor signaling pathway;GO:0002720//positive regulation of cytokine production involved in immune response;GO:0042593//glucose homeostasis;GO:0071398//cellular response to fatty acid;GO:0090276//regulation of peptide hormone secretion;GO:0002673//regulation of acute inflammatory response;GO:0002879//positive regulation of acute inflammatory response to non-antigenic stimulus;GO:0019915//lipid storage;GO:2000484//positive regulation of interleukin-8 secretion;GO:0045444//fat cell differentiation;GO:0032722//positive regulation of chemokine production;GO:0002752//cell surface pattern recognition receptor signaling pathway;GO:0002385//mucosal immune response","K04328//free fatty acid receptor 2","NP_005297.1//free fatty acid receptor 2 [Homo sapiens]","2//1"]
[9524,1180,151.51,200.36,0.403181498757468,{"v":4.14286168263473e-22,"d":"4.14E-22"},"*",{"v":1.73246e-23,"d":"1.73E-23"},"TECR","GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005737//cytoplasm","GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors;GO:0017099//very-long-chain-acyl-CoA dehydrogenase activity;GO:0016491//oxidoreductase activity","GO:0030497//fatty acid elongation;GO:0035338//long-chain fatty-acyl-CoA biosynthetic process;GO:0042761//very long-chain fatty acid biosynthetic process;GO:0006629//lipid metabolic process","K10258//very-long-chain enoyl-CoA reductase [EC:1.3.1.93]","NP_001308099.1//very-long-chain enoyl-CoA reductase isoform 2 [Homo sapiens];NP_612510.1//very-long-chain enoyl-CoA reductase isoform 1 [Homo sapiens]","1//3;5"]
[64288,3176,0.56,0.74,0.402098443571346,0.632344384186434,"*",0.475624,"ZSCAN31","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein;K09230//SCAN domain-containing zinc finger protein","XP_020032604.1//zinc finger protein with KRAB and SCAN domains 4 isoform X1 [Castor canadensis];XP_007972111.1//PREDICTED: LOW QUALITY PROTEIN: zinc finger and SCAN domain-containing protein 12 [Chlorocebus sabaeus]","4;1//3;2//1"]
[57018,2946,12.44,16.43,0.401345994819472,{"v":7.94157590538765e-06,"d":"7.94E-06"},"*",{"v":1.513344e-06,"d":"1.51E-06"},"CCNL1","GO:0005634//nucleus;GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0016607//nuclear speck","GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity","GO:0006396//RNA processing;GO:1901409//positive regulation of phosphorylation of RNA polymerase II C-terminal domain;GO:0006355//regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity","K13170//splicing factor, arginine/serine-rich 18;K13165//splicing factor, arginine/serine-rich 12;K02333//DNA polymerase gamma 2","NP_064703.1//cyclin-L1 isoform 1 [Homo sapiens];NP_001295114.1//cyclin-L1 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[35,1964,4.34,5.73,0.400840096312426,0.066416220758483,"*",0.0291626,"ACADS","GO:0005759//mitochondrial matrix;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion","GO:0004085//butyryl-CoA dehydrogenase activity;GO:0050660//flavin adenine dinucleotide binding;GO:0003995//acyl-CoA dehydrogenase activity","GO:0033539//fatty acid beta-oxidation using acyl-CoA dehydrogenase;GO:0006635//fatty acid beta-oxidation","K00248//butyryl-CoA dehydrogenase [EC:1.3.8.1]","NP_001289483.1//short-chain specific acyl-CoA dehydrogenase, mitochondrial isoform 2 precursor [Homo sapiens];NP_000008.1//short-chain specific acyl-CoA dehydrogenase, mitochondrial isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[149473,1381,9.18,12.11,0.399632806280521,0.0685767745986646,"*",0.0302186,"CCDC24","NA","NA","NA","K05038//solute carrier family 6 (neurotransmitter transporter, amino acid) member 5/7/9/14;K02184//formin 2","NP_001336056.1//coiled-coil domain-containing protein 24 isoform 2 [Homo sapiens];NP_689712.1//coiled-coil domain-containing protein 24 isoform 1 [Homo sapiens];NP_001336057.1//coiled-coil domain-containing protein 24 isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[29888,3228,76.58,100.84,0.397028458008379,{"v":4.89381949656751e-30,"d":"4.89E-30"},"*",{"v":1.3388E-31,"d":"1.34E-31"},"STRN4","GO:0016020//membrane;GO:0043234//protein complex;GO:0043197//dendritic spine;GO:0005737//cytoplasm","GO:0070016//armadillo repeat domain binding;GO:0005516//calmodulin binding;GO:0051721//protein phosphatase 2A binding;GO:0032403//protein complex binding","NA","K17608//striatin 1/3/4","NP_001034966.1//striatin-4 isoform 2 [Homo sapiens];NP_037535.2//striatin-4 isoform 1 [Homo sapiens]","1//3;2//1"]
[60370,1422,70.39,92.68,0.396887558168959,{"v":1.92570240175055E-12,"d":"1.93E-12"},"*",{"v":1.652772E-13,"d":"1.65E-13"},"AVPI1","NA","NA","GO:0000187//activation of MAPK activity;GO:0007049//cell cycle","NA","NP_068378.2//arginine vasopressin-induced protein 1 [Homo sapiens]","2//1"]
[11277,1954,10.73,14.11,0.395067911840742,0.00452192079545899,"*",0.001446256,"TREX1","GO:0005635//nuclear envelope;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0032407//MutSalpha complex binding;GO:0042803//protein homodimerization activity;GO:0003676//nucleic acid binding;GO:0032405//MutLalpha complex binding;GO:0008408//3'-5' exonuclease activity;GO:0046872//metal ion binding;GO:0003697//single-stranded DNA binding;GO:0008853//exodeoxyribonuclease III activity;GO:0008296//3'-5'-exodeoxyribonuclease activity","GO:0006281//DNA repair;GO:0032479//regulation of type I interferon production;GO:0006298//mismatch repair;GO:0006260//DNA replication;GO:0006310//DNA recombination;GO:0006259//DNA metabolic process","K10790//three prime repair exonuclease 1 [EC:3.1.11.2]","XP_011836380.1//PREDICTED: three-prime repair exonuclease 1 isoform X2 [Mandrillus leucophaeus];XP_002802855.1//PREDICTED: three-prime repair exonuclease 1 [Macaca mulatta];NP_057465.1//three-prime repair exonuclease 1 isoform a [Homo sapiens]","4;3//A2MP1;5"]
[118472,1128,43.48,57.11,0.393391444229038,{"v":2.04572004181687E-6,"d":"2.05E-06"},"*",{"v":3.55254e-07,"d":"3.55E-07"},"ZNF511","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K01230//mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113];K14802//phospholipid-transporting ATPase [EC:3.6.3.1];K19720//collagen, type III, alpha","AAH15139.1//ZNF511 protein, partial [Homo sapiens]","3//A2MP1"]
[1259,2864,0.16,0.21,0.39231742277876,0.695792519421861,"*",0.578622,"CNGA1","GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0042622//photoreceptor outer segment membrane","GO:0005249//voltage-gated potassium channel activity;GO:0005221//intracellular cyclic nucleotide activated cation channel activity;GO:0030553//cGMP binding","GO:0006810//transport;GO:0016056//rhodopsin mediated signaling pathway;GO:0007601//visual perception;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0042391//regulation of membrane potential","K04948//cyclic nucleotide gated channel alpha 1","NP_001136036.1//cGMP-gated cation channel alpha-1 isoform 1 [Homo sapiens];XP_014993822.1//PREDICTED: cGMP-gated cation channel alpha-1 [Macaca mulatta]","1//3;3//A2MP1"]
[284131,1565,11.39,14.94,0.391412401081125,0.0169790126975477,"*",6.24144E-3,"ENDOV","GO:0005730//nucleolus;GO:0005737//cytoplasm","GO:0000287//magnesium ion binding;GO:0003677//DNA binding;GO:0016891//endoribonuclease activity, producing 5'-phosphomonoesters;GO:0016888//endodeoxyribonuclease activity, producing 5'-phosphomonoesters;GO:0004519//endonuclease activity;GO:0003727//single-stranded RNA binding","GO:0006281//DNA repair","K21813//endonuclease V [EC:3.1.26.-]","NP_001339690.1//endonuclease V isoform 5 [Homo sapiens];NP_775898.2//endonuclease V isoform 1 [Homo sapiens];EAW89609.1//hypothetical protein FLJ35220, isoform CRA_g [Homo sapiens];NP_001339689.1//endonuclease V isoform 4 [Homo sapiens];NP_001158110.1//endonuclease V isoform 3 [Homo sapiens]","4;1//3;2//1"]
[3105,1632,66.56,87.18,0.389341770212905,{"v":5.53218607804132e-13,"d":"5.53E-13"},"*",{"v":4.52646E-14,"d":"4.53E-14"},"HLA-A","NA","NA","NA","K06751//major histocompatibility complex, class I","ALO24308.1//MHC class I antigen [Homo sapiens];P13746.1//RecName: Full=HLA class I histocompatibility antigen, A-11 alpha chain; AltName: Full=MHC class I antigen A*11; Flags: Precursor","1//3;7"]
[6195,3095,8.67,11.34,0.387316741720394,0.000798495999087799,"*",2.19194E-4,"RPS6KA1","NA","NA","NA","K04373//ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]","XP_009941834.1//PREDICTED: ribosomal protein S6 kinase alpha-1 [Opisthocomus hoazin];XP_020014345.1//ribosomal protein S6 kinase alpha-1 isoform X2 [Castor canadensis];XP_009906870.1//PREDICTED: ribosomal protein S6 kinase alpha-1 [Picoides pubescens]","1//3;3//A2MP1"]
[5788,1477,0.88,1.15,0.386058432307078,0.570702319620526,"*",0.414254,"PTPRC","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0030667//secretory granule membrane;GO:0005925//focal adhesion;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0045121//membrane raft;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005001//transmembrane receptor protein tyrosine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0019901//protein kinase binding","GO:2000473//positive regulation of hematopoietic stem cell migration;GO:0002378//immunoglobulin biosynthetic process;GO:0048539//bone marrow development;GO:0002244//hematopoietic progenitor cell differentiation;GO:0042102//positive regulation of T cell proliferation;GO:0007166//cell surface receptor signaling pathway;GO:0010332//response to gamma radiation;GO:0030890//positive regulation of B cell proliferation;GO:2000648//positive regulation of stem cell proliferation;GO:0048864//stem cell development;GO:0001915//negative regulation of T cell mediated cytotoxicity;GO:0006470//protein dephosphorylation;GO:0045860//positive regulation of protein kinase activity;GO:0043312//neutrophil degranulation;GO:0016311//dephosphorylation;GO:0001960//negative regulation of cytokine-mediated signaling pathway;GO:0050853//B cell receptor signaling pathway;GO:0050852//T cell receptor signaling pathway;GO:0051607//defense response to virus;GO:0006933//negative regulation of cell adhesion involved in substrate-bound cell migration;GO:0006469//negative regulation of protein kinase activity;GO:0044770//cell cycle phase transition;GO:0042100//B cell proliferation;GO:0050857//positive regulation of antigen receptor-mediated signaling pathway;GO:0030217//T cell differentiation;GO:0051726//regulation of cell cycle;GO:0051209//release of sequestered calcium ion into cytosol","K06478//receptor-type tyrosine-protein phosphatase C [EC:3.1.3.48]","NP_563578.2//receptor-type tyrosine-protein phosphatase C isoform 2 precursor [Homo sapiens];NP_002829.3//receptor-type tyrosine-protein phosphatase C isoform 1 precursor [Homo sapiens];NP_001254727.1//receptor-type tyrosine-protein phosphatase C isoform 5 precursor [Homo sapiens]","4;1//3;3//A2MP1"]
[131616,997,7.02,9.17,0.385450703290494,0.126962470097787,"*",0.0617724,"TMEM42","GO:0016021//integral component of membrane","NA","NA","K03767//peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8];K10400//kinesin family member 15","NP_653239.1//transmembrane protein 42 [Homo sapiens]","2//1"]
[1603,711,352.44,459.65,0.383158069108334,{"v":7.68599595180723e-27,"d":"7.69E-27"},"*",{"v":2.39616e-28,"d":"2.40E-28"},"DAD1","NA","NA","NA","K12668//oligosaccharyltransferase complex subunit epsilon","XP_006217276.2//PREDICTED: dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 [Vicugna pacos]","3//A2MP1"]
[4151,1078,2.51,3.27,0.381603271547311,0.397323078264239,"*",0.25679,"MB","GO:0070062//extracellular exosome;GO:0005829//cytosol","GO:0046872//metal ion binding;GO:0020037//heme binding;GO:0005344//oxygen carrier activity;GO:0019825//oxygen binding","GO:0015671//oxygen transport;GO:0031444//slow-twitch skeletal muscle fiber contraction;GO:0043353//enucleate erythrocyte differentiation;GO:0007507//heart development;GO:0009725//response to hormone;GO:0050873//brown fat cell differentiation;GO:0042542//response to hydrogen peroxide;GO:0001666//response to hypoxia","K21892//myoglobin","XP_003264736.1//PREDICTED: myoglobin isoform X1 [Nomascus leucogenys];EAW60065.1//myoglobin, isoform CRA_a [Homo sapiens]","1//3;2//1"]
[55630,763,67.56,87.97,0.380842283902436,{"v":8.32749347877204e-06,"d":"8.33E-06"},"*",{"v":1.596268E-6,"d":"1.60E-06"},"SLC39A4","GO:0070062//extracellular exosome;GO:0055038//recycling endosome membrane;GO:0005887//integral component of plasma membrane;GO:0016324//apical plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0005886//plasma membrane","GO:0005385//zinc ion transmembrane transporter activity","GO:0071578//zinc II ion transmembrane import;GO:0034224//cellular response to zinc ion starvation;GO:0007165//signal transduction;GO:0006882//cellular zinc ion homeostasis","K14710//solute carrier family 39 (zinc transporter), member 4","XP_008000121.1//PREDICTED: zinc transporter ZIP4 [Chlorocebus sabaeus];NP_570901.2//zinc transporter ZIP4 isoform 2 precursor [Homo sapiens];NP_060237.2//zinc transporter ZIP4 isoform 1 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[81858,1816,53.54,69.62,0.378884675082905,{"v":3.94519144800523e-11,"d":"3.95E-11"},"*",{"v":3.77626e-12,"d":"3.78E-12"},"SHARPIN","GO:0030425//dendrite;GO:0071797//LUBAC complex;GO:0005829//cytosol;GO:0030054//cell junction;GO:0014069//postsynaptic density","GO:0046872//metal ion binding;GO:0031593//polyubiquitin modification-dependent protein binding;GO:0042802//identical protein binding;GO:0004842//ubiquitin-protein transferase activity;GO:0032403//protein complex binding","GO:0051260//protein homooligomerization;GO:0031424//keratinization;GO:0030262//apoptotic nuclear changes;GO:0010803//regulation of tumor necrosis factor-mediated signaling pathway;GO:0050728//negative regulation of inflammatory response;GO:0007420//brain development;GO:0007005//mitochondrion organization;GO:2000348//regulation of CD40 signaling pathway;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0097039//protein linear polyubiquitination","K20894//shank-associated RH domain-interacting protein","NP_112236.3//sharpin [Homo sapiens]","3//A2MP1"]
[116412,1948,1.9,2.47,0.37851162325373,0.295215336519503,"*",0.1724646,"ZNF837","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_007505752.1//PREDICTED: zinc finger protein 497 [Monodelphis domestica]","1//3"]
[202051,719,1.17,1.52,0.377562793860181,0.658102871755608,"*",0.538092,"SPATA24","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0042803//protein homodimerization activity","GO:0030154//cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0007275//multicellular organism development;GO:0006351//transcription, DNA-templated;GO:0007283//spermatogenesis","K12327//caldesmon;K04559//huntingtin interacting protein 1;K20283//golgin subfamily A member 4;K12478//early endosome antigen 1;K20478//golgin subfamily B member 1","XP_022349019.1//spermatogenesis-associated protein 24 [Enhydra lutris kenyoni]","1//3"]
[116444,3299,0.67,0.87,0.376854305390956,0.467379441903357,"*",0.317282,"GRIN3B","GO:0017146//NMDA selective glutamate receptor complex;GO:0098794//postsynapse;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0005886//plasma membrane;GO:0045211//postsynaptic membrane;GO:0043025//neuronal cell body","GO:0016594//glycine binding;GO:0004970//ionotropic glutamate receptor activity;GO:0005234//extracellularly glutamate-gated ion channel activity;GO:0042165//neurotransmitter binding;GO:0005262//calcium channel activity;GO:0030594//neurotransmitter receptor activity;GO:0005261//cation channel activity","GO:0051924//regulation of calcium ion transport;GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0051205//protein insertion into membrane","K05214//glutamate receptor ionotropic, NMDA 3B","NP_619635.1//glutamate receptor ionotropic, NMDA 3B precursor [Homo sapiens]","2//1"]
[269,1844,0.47,0.61,0.376148485885249,0.672187182191156,"*",0.553858,"AMHR2","GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane","GO:1990272//anti-Mullerian hormone receptor activity;GO:0046872//metal ion binding;GO:0005524//ATP binding;GO:0004872//receptor activity;GO:0004702//signal transducer, downstream of receptor, with serine/threonine kinase activity;GO:0042562//hormone binding;GO:0005026//transforming growth factor beta receptor activity, type II","GO:1902613//negative regulation of anti-Mullerian hormone signaling pathway;GO:0007165//signal transduction;GO:0030509//BMP signaling pathway;GO:0008584//male gonad development;GO:0008585//female gonad development;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007548//sex differentiation;GO:0001880//Mullerian duct regression","K04672//anti-mullerian hormone receptor type-2 [EC:2.7.11.30]","NP_001158162.1//anti-Muellerian hormone type-2 receptor isoform 2 precursor [Homo sapiens];NP_001158163.1//anti-Muellerian hormone type-2 receptor isoform 3 precursor [Homo sapiens];NP_065434.1//anti-Muellerian hormone type-2 receptor isoform 1 precursor [Homo sapiens]","3//A2MP1;2//1"]
[147699,1718,1.92,2.49,0.375039431346925,0.352146928483354,"*",0.214542,"PPM1N","NA","GO:0000287//magnesium ion binding;GO:0004722//protein serine/threonine phosphatase activity;GO:0030145//manganese ion binding","NA","K19790//protein phosphatase 1N [EC:3.1.3.16]","NP_001073870.1//probable protein phosphatase 1N [Homo sapiens]","1//3"]
[199800,2112,7.59,9.83,0.373091530925114,0.0152222239696237,"*",0.00552132,"ADM5","GO:0005576//extracellular region","NA","NA","NA","XP_004061227.1//PREDICTED: putative adrenomedullin-5-like protein [Gorilla gorilla gorilla]","1//3"]
[11140,1693,131.44,170.13,0.372233176735428,{"v":1.68652193300813E-23,"d":"1.69E-23"},"*",{"v":6.49312e-25,"d":"6.49E-25"},"CDC37","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:1990565//HSP90-CDC37 chaperone complex;GO:0005737//cytoplasm","GO:0031072//heat shock protein binding;GO:0051087//chaperone binding;GO:0019901//protein kinase binding;GO:0051879//Hsp90 protein binding;GO:0004713//protein tyrosine kinase activity;GO:0019887//protein kinase regulator activity;GO:0051082//unfolded protein binding;GO:0019900//kinase binding","GO:0006605//protein targeting;GO:0006457//protein folding;GO:0098779//positive regulation of mitophagy in response to mitochondrial depolarization;GO:0038128//ERBB2 signaling pathway;GO:0010608//posttranscriptional regulation of gene expression;GO:0051301//cell division;GO:0060338//regulation of type I interferon-mediated signaling pathway;GO:0060334//regulation of interferon-gamma-mediated signaling pathway;GO:0050821//protein stabilization;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity","K09554//cell division cycle protein 37","NP_008996.1//hsp90 co-chaperone Cdc37 [Homo sapiens]","3//A2MP1"]
[7001,1052,1.09,1.41,0.371367027621867,0.639370064590924,"*",0.48335,"PRDX2","GO:0070062//extracellular exosome;GO:0005623//cell;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0016209//antioxidant activity;GO:0008379//thioredoxin peroxidase activity;GO:0051920//peroxiredoxin activity","GO:0006979//response to oxidative stress;GO:0019430//removal of superoxide radicals;GO:0034599//cellular response to oxidative stress;GO:0043066//negative regulation of apoptotic process;GO:0042744//hydrogen peroxide catabolic process;GO:0042981//regulation of apoptotic process;GO:0045454//cell redox homeostasis","K03386//peroxiredoxin (alkyl hydroperoxide reductase subunit C) [EC:1.11.1.15]","NP_005800.3//peroxiredoxin-2 [Homo sapiens]",5]
[6169,377,623.2,805.31,0.36984901488496,{"v":6.08406779941003e-22,"d":"6.08E-22"},"*",{"v":2.58232E-23,"d":"2.58E-23"},"RPL38","NA","NA","NA","K02923//large subunit ribosomal protein L38e","XP_008010096.1//PREDICTED: 60S ribosomal protein L38 isoform X3 [Chlorocebus sabaeus]","1//3;3//A2MP1"]
[653082,3051,0.24,0.31,0.369233809665719,0.641481626726333,"*",0.520486,"ZDHHC11B","NA","NA","NA","K20027//palmitoyltransferase ZDHHC1/11 [EC:2.3.1.225]","NP_001338232.1//probable palmitoyltransferase ZDHHC11B [Homo sapiens]","1//3"]
[128229,557,6.07,7.83,0.367315791035359,0.816122745179926,"*",0.73402,"TSACC","GO:0005737//cytoplasm","GO:0051087//chaperone binding","NA","K15696//RING finger protein 113B;K06580//ammonium transporter Rh;K01064//wingless-type MMTV integration site family, member 9","NP_001291755.1//TSSK6-activating co-chaperone protein isoform c [Homo sapiens];XP_017365500.1//PREDICTED: TSSK6-activating co-chaperone protein isoform X2 [Cebus capucinus imitator];XP_018880014.1//PREDICTED: TSSK6-activating co-chaperone protein isoform X2 [Gorilla gorilla gorilla];XP_004027019.1//PREDICTED: TSSK6-activating co-chaperone protein isoform X1 [Gorilla gorilla gorilla]","4;1//3"]
[5694,869,173.54,223.74,0.36655496866941,{"v":2.79759449487179e-15,"d":"2.80E-15"},"*",{"v":1.912466E-16,"d":"1.91E-16"},"PSMB6","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000502//proteasome complex;GO:0005829//cytosol;GO:0019774//proteasome core complex, beta-subunit complex;GO:0005839//proteasome core complex","GO:0004175//endopeptidase activity;GO:0004298//threonine-type endopeptidase activity;GO:0045296//cadherin binding","GO:0043687//post-translational protein modification;GO:0038061//NIK/NF-kappaB signaling;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0006521//regulation of cellular amino acid metabolic process;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0016579//protein deubiquitination;GO:0043488//regulation of mRNA stability;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0000209//protein polyubiquitination;GO:0055085//transmembrane transport;GO:0000165//MAPK cascade;GO:0050852//T cell receptor signaling pathway;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0016032//viral process;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:1902036//regulation of hematopoietic stem cell differentiation","K02738//20S proteasome subunit beta 1 [EC:3.4.25.1]","XP_008008144.1//PREDICTED: proteasome subunit beta type-6 isoform X1 [Chlorocebus sabaeus];XP_008008145.1//PREDICTED: proteasome subunit beta type-6 isoform X2 [Chlorocebus sabaeus]","1//3;2//1"]
[51181,854,56.04,72.18,0.365142187466415,{"v":2.23112103249317E-5,"d":"2.23E-05"},"*",{"v":4.5994e-06,"d":"4.60E-06"},"DCXR","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005903//brush border;GO:0005881//cytoplasmic microtubule;GO:0005886//plasma membrane;GO:0005902//microvillus","GO:0042802//identical protein binding;GO:0050038//L-xylulose reductase (NADP+) activity;GO:0016655//oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor","GO:0019640//glucuronate catabolic process to xylulose 5-phosphate;GO:0006006//glucose metabolic process;GO:0005997//xylulose metabolic process;GO:0006739//NADP metabolic process;GO:0051289//protein homotetramerization;GO:0042732//D-xylose metabolic process;GO:0055114//oxidation-reduction process","K03331//L-xylulose reductase [EC:1.1.1.10]","NP_057370.1//L-xylulose reductase isoform 1 [Homo sapiens];NP_001182147.1//L-xylulose reductase isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[133,1606,27.01,34.75,0.363519337989265,{"v":4.28973421940685e-05,"d":"4.29E-05"},"*",{"v":9.32656e-06,"d":"9.33E-06"},"ADM","GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0005102//receptor binding;GO:0031700//adrenomedullin receptor binding;GO:0005179//hormone activity","GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0031100//animal organ regeneration;GO:0031623//receptor internalization;GO:0045906//negative regulation of vasoconstriction;GO:0043065//positive regulation of apoptotic process;GO:0043116//negative regulation of vascular permeability;GO:0060712//spongiotrophoblast layer development;GO:0045766//positive regulation of angiogenesis;GO:0001570//vasculogenesis;GO:0030819//positive regulation of cAMP biosynthetic process;GO:0008285//negative regulation of cell proliferation;GO:0009611//response to wounding;GO:0046879//hormone secretion;GO:0007565//female pregnancy;GO:0007165//signal transduction;GO:0008209//androgen metabolic process;GO:0007507//heart development;GO:0001666//response to hypoxia;GO:0042475//odontogenesis of dentin-containing tooth;GO:0019933//cAMP-mediated signaling;GO:0003073//regulation of systemic arterial blood pressure;GO:0008015//blood circulation;GO:0001843//neural tube closure;GO:0019731//antibacterial humoral response;GO:0097084//vascular smooth muscle cell development;GO:0050829//defense response to Gram-negative bacterium;GO:0032496//response to lipopolysaccharide;GO:0097647//amylin receptor signaling pathway;GO:0030816//positive regulation of cAMP metabolic process;GO:0031102//neuron projection regeneration;GO:0050830//defense response to Gram-positive bacterium;GO:0051384//response to glucocorticoid;GO:0010460//positive regulation of heart rate;GO:0032868//response to insulin;GO:0009409//response to cold;GO:0035809//regulation of urine volume;GO:2001214//positive regulation of vasculogenesis;GO:0007267//cell-cell signaling;GO:0006701//progesterone biosynthetic process;GO:0006171//cAMP biosynthetic process;GO:0007568//aging;GO:0002026//regulation of the force of heart contraction;GO:0060670//branching involved in labyrinthine layer morphogenesis;GO:0042594//response to starvation;GO:0048589//developmental growth;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0002031//G-protein coupled receptor internalization;GO:0008284//positive regulation of cell proliferation","K12333//adrenomedullin","NP_001115.1//ADM precursor [Homo sapiens]","2//1"]
[100526693,3987,2.97,3.82,0.363109707234983,0.0511483059758611,"*",0.0217542,"ARPC4-TTLL3","GO:0005885//Arp2/3 protein complex","GO:0005524//ATP binding;GO:0070735//protein-glycine ligase activity","GO:0034314//Arp2/3 complex-mediated actin nucleation;GO:0018094//protein polyglycylation;GO:0030041//actin filament polymerization","K16608//tubulin monoglycylase TTLL3/8 [EC:6.3.2.-]","NP_001185722.1//ARPC4-TTLL3 fusion protein [Homo sapiens]","1//3"]
[29944,3647,0.07,0.09,0.362570079384708,0.811237322397476,"*",0.724446,"PNMA3","GO:0005730//nucleolus","GO:0008270//zinc ion binding;GO:0003676//nucleic acid binding","GO:0043065//positive regulation of apoptotic process","K17561//coiled-coil domain-containing protein 8;K02183//calmodulin;K12015//tripartite motif-containing protein 39 [EC:2.3.2.27]","NP_001269464.1//paraneoplastic antigen Ma3 isoform 2 [Homo sapiens];NP_037496.4//paraneoplastic antigen Ma3 isoform 1 [Homo sapiens]","1//3;5"]
[2987,963,51.79,66.58,0.362415312009415,{"v":9.64705095875899e-07,"d":"9.65E-07"},"*",{"v":1.596166E-7,"d":"1.60E-07"},"GUK1","GO:0005829//cytosol","GO:0005524//ATP binding;GO:0004385//guanylate kinase activity","GO:0034436//glycoprotein transport;GO:0046034//ATP metabolic process;GO:0046711//GDP biosynthetic process;GO:0046054//dGMP metabolic process;GO:0019673//GDP-mannose metabolic process;GO:0015949//nucleobase-containing small molecule interconversion;GO:0046060//dATP metabolic process;GO:0006185//dGDP biosynthetic process;GO:0006163//purine nucleotide metabolic process","K00942//guanylate kinase [EC:2.7.4.8]","NP_001229769.1//guanylate kinase isoform c [Homo sapiens];NP_001152862.1//guanylate kinase isoform a [Homo sapiens];XP_018887051.1//PREDICTED: guanylate kinase isoform X2 [Gorilla gorilla gorilla]","1//3;5"]
[205251,2054,15.43,19.82,0.361218900615753,0.000631024384895105,"*",0.0001694688,"SMIM37","NA","NA","NA","K13024//inositol-hexakisphosphate/diphosphoinositol-pentakisphosphate 1-kinase [EC:2.7.4.24];K12606//CCR4-NOT transcription complex subunit 9;K17985//activating molecule in BECN1-regulated autophagy protein 1","NP_001342180.1//uncharacterized protein encoded by LINC00116 [Homo sapiens]","1//3"]
[7057,7253,4.59,5.89,0.359773480416653,0.000377957681461632,"*",{"v":9.71276e-05,"d":"9.71E-05"},"THBS1","GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0005577//fibrinogen complex;GO:0031091//platelet alpha granule;GO:0009897//external side of plasma membrane","GO:0070052//collagen V binding;GO:0030169//low-density lipoprotein particle binding;GO:0001968//fibronectin binding;GO:0043236//laminin binding;GO:0005178//integrin binding;GO:0005509//calcium ion binding;GO:0017134//fibroblast growth factor binding;GO:0008201//heparin binding;GO:0001786//phosphatidylserine binding;GO:0070051//fibrinogen binding","GO:0010763//positive regulation of fibroblast migration;GO:0010751//negative regulation of nitric oxide mediated signal transduction;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0016477//cell migration;GO:0032026//response to magnesium ion;GO:0030823//regulation of cGMP metabolic process;GO:0051918//negative regulation of fibrinolysis;GO:0002581//negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;GO:0018149//peptide cross-linking;GO:0010748//negative regulation of plasma membrane long-chain fatty acid transport;GO:0009749//response to glucose;GO:0045766//positive regulation of angiogenesis;GO:0001937//negative regulation of endothelial cell proliferation;GO:0042493//response to drug;GO:0043032//positive regulation of macrophage activation;GO:0040037//negative regulation of fibroblast growth factor receptor signaling pathway;GO:2001027//negative regulation of endothelial cell chemotaxis;GO:0043652//engulfment of apoptotic cell;GO:0002605//negative regulation of dendritic cell antigen processing and presentation;GO:0051592//response to calcium ion;GO:1902043//positive regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0007155//cell adhesion;GO:0050921//positive regulation of chemotaxis;GO:0002544//chronic inflammatory response;GO:0001953//negative regulation of cell-matrix adhesion;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0002040//sprouting angiogenesis;GO:0051897//positive regulation of protein kinase B signaling;GO:0032695//negative regulation of interleukin-12 production;GO:0045727//positive regulation of translation;GO:0007050//cell cycle arrest;GO:2000353//positive regulation of endothelial cell apoptotic process;GO:0010754//negative regulation of cGMP-mediated signaling;GO:0000187//activation of MAPK activity;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0016525//negative regulation of angiogenesis;GO:0010757//negative regulation of plasminogen activation;GO:0042535//positive regulation of tumor necrosis factor biosynthetic process;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0006955//immune response;GO:0043537//negative regulation of blood vessel endothelial cell migration;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway","K16857//thrombospondin 1","BAD93149.1//thrombospondin 1 precursor variant, partial [Homo sapiens]","3//A2MP1"]
[2787,823,126.38,162.17,0.359738787633154,{"v":2.18763785395293E-10,"d":"2.19E-10"},"*",{"v":2.26926E-11,"d":"2.27E-11"},"GNG5","NA","NA","NA","K04542//guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5","XP_018878468.1//PREDICTED: guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 isoform X1 [Gorilla gorilla gorilla]","2//1"]
[9260,1594,56.91,72.92,0.357632381906502,{"v":1.33314411722429e-10,"d":"1.33E-10"},"*",{"v":1.346998E-11,"d":"1.35E-11"},"PDLIM7","GO:0001726//ruffle;GO:0001725//stress fiber;GO:0005634//nucleus;GO:0005925//focal adhesion;GO:0005913//cell-cell adherens junction;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0005737//cytoplasm","GO:0046872//metal ion binding","GO:0030036//actin cytoskeleton organization;GO:0006898//receptor-mediated endocytosis;GO:0045669//positive regulation of osteoblast differentiation;GO:0001503//ossification;GO:0007411//axon guidance","K19867//LIM domain-binding protein 3","XP_008013637.1//PREDICTED: PDZ and LIM domain protein 7 isoform X3 [Chlorocebus sabaeus];XP_008013635.1//PREDICTED: PDZ and LIM domain protein 7 isoform X1 [Chlorocebus sabaeus];XP_008013640.1//PREDICTED: PDZ and LIM domain protein 7 isoform X5 [Chlorocebus sabaeus]","4;2//1"]
[10046,4532,2.04,2.61,0.355480654598389,0.0794673239311494,"*",0.0358384,"MAMLD1","GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0005794//Golgi apparatus;GO:0005813//centrosome","NA","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0008584//male gonad development","K19512//mastermind-like domain-containing protein 1","NP_001170936.1//mastermind-like domain-containing protein 1 isoform 1 [Homo sapiens];NP_001170937.1//mastermind-like domain-containing protein 1 isoform 3 [Homo sapiens];NP_005482.2//mastermind-like domain-containing protein 1 isoform 2 [Homo sapiens]","4;2//1"]
[6781,3897,4.01,5.13,0.355356589152134,0.0232622649729907,"*",0.00889628,"STC1","GO:0005634//nucleus;GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0005179//hormone activity","GO:0001886//endothelial cell morphogenesis;GO:0010596//negative regulation of endothelial cell migration;GO:0003421//growth plate cartilage axis specification;GO:0051926//negative regulation of calcium ion transport;GO:0044070//regulation of anion transport;GO:0035988//chondrocyte proliferation;GO:0090280//positive regulation of calcium ion import;GO:1903403//negative regulation of renal phosphate excretion;GO:0086004//regulation of cardiac muscle cell contraction;GO:0006874//cellular calcium ion homeostasis","K04650//nuclear receptor co-repressor 1","XP_006028766.1//PREDICTED: stanniocalcin-1 [Alligator sinensis]","2//1"]
[79897,561,72.46,92.55,0.353048184304649,0.000272696653323301,"*",{"v":6.80632e-05,"d":"6.81E-05"},"RPP21","GO:0005654//nucleoplasm;GO:0030681//multimeric ribonuclease P complex;GO:0005655//nucleolar ribonuclease P complex","GO:0046872//metal ion binding;GO:0004526//ribonuclease P activity","GO:0042493//response to drug;GO:0001682//tRNA 5'-leader removal;GO:0006364//rRNA processing;GO:0008033//tRNA processing","K03540//ribonuclease P protein subunit RPR2 [EC:3.1.26.5]","XP_007971483.1//PREDICTED: ribonuclease P protein subunit p21 isoform X1 [Chlorocebus sabaeus];XP_007971484.1//PREDICTED: ribonuclease P protein subunit p21 isoform X2 [Chlorocebus sabaeus];NP_001186049.1//ribonuclease P protein subunit p21 isoform 1 [Homo sapiens]","1//3;2//1"]
[9124,1598,93.18,118.79,0.35032115649181,{"v":3.71869350588235e-14,"d":"3.72E-14"},"*",{"v":2.77028e-15,"d":"2.77E-15"},"PDLIM1","GO:0005856//cytoskeleton;GO:0005925//focal adhesion;GO:0005913//cell-cell adherens junction;GO:0005667//transcription factor complex;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0098641//cadherin binding involved in cell-cell adhesion;GO:0003713//transcription coactivator activity","GO:0006979//response to oxidative stress;GO:0006355//regulation of transcription, DNA-templated;GO:0001666//response to hypoxia","K19867//LIM domain-binding protein 3","NP_066272.1//PDZ and LIM domain protein 1 [Homo sapiens]","3//A2MP1"]
[83719,977,9.25,11.79,0.350038447576088,0.345813376237624,"*",0.209904,"YPEL3","GO:0005730//nucleolus","GO:0046872//metal ion binding","GO:2000774//positive regulation of cellular senescence","K14697//solute carrier family 30 (zinc transporter), member 10;K18080//tensin;K12567//titin [EC:2.7.11.1]","XP_011980257.1//PREDICTED: protein yippee-like 3 isoform X2, partial [Ovis aries musimon];XP_012319981.1//protein yippee-like 3 isoform X2 [Aotus nancymaae]","1//3;4"]
[9507,4346,1.32,1.68,0.347923303420307,0.179830332839034,"*",0.0941368,"ADAMTS4","GO:0031012//extracellular matrix;GO:0005615//extracellular space;GO:0016607//nuclear speck;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix","GO:0002020//protease binding;GO:0008233//peptidase activity;GO:0008237//metallopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding","GO:0022617//extracellular matrix disassembly;GO:0006508//proteolysis;GO:0001501//skeletal system development","K07764//a disintegrin and metalloproteinase with thrombospondin motifs 4 [EC:3.4.24.82]","XP_017370582.1//PREDICTED: A disintegrin and metalloproteinase with thrombospondin motifs 4 isoform X1 [Cebus capucinus imitator];NP_001307265.1//A disintegrin and metalloproteinase with thrombospondin motifs 4 isoform 2 precursor [Homo sapiens]","1//3;5"]
[124641,1076,89.14,113.4,0.347275774216937,{"v":3.49710293723849e-09,"d":"3.50E-09"},"*",{"v":4.18584E-10,"d":"4.19E-10"},"OVCA2","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0016787//hydrolase activity","GO:0032526//response to retinoic acid","K07561//2-(3-amino-3-carboxypropyl)histidine synthase [EC:2.5.1.108]","NP_543012.1//esterase OVCA2 [Homo sapiens]","2//1"]
[9311,2291,10.4,13.23,0.347229533250222,0.0040923767586343,"*",1.298114E-3,"ASIC3","NA","NA","NA","K04830//acid-sensing ion channel 3","XP_003815113.1//PREDICTED: acid-sensing ion channel 3 isoform X3 [Pan paniscus];XP_003815115.1//PREDICTED: acid-sensing ion channel 3 isoform X1 [Pan paniscus];XP_003815114.1//PREDICTED: acid-sensing ion channel 3 isoform X2 [Pan paniscus]","3//A2MP1"]
[169841,2602,0.37,0.47,0.345135486048687,0.595939190755374,"*",0.439064,"ZNF169","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","XP_003912049.3//zinc finger protein 169 isoform X2 [Papio anubis];XP_009187478.2//zinc finger protein 169 isoform X1 [Papio anubis];XP_011769568.1//PREDICTED: zinc finger protein 169 isoform X1 [Macaca nemestrina]","1//3;3//A2MP1;2//1"]
[150372,5570,0.26,0.33,0.343954401217361,0.498926269967474,"*",0.345694,"NFAM1","GO:0009986//cell surface;GO:0045121//membrane raft;GO:0005622//intracellular;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0035577//azurophil granule membrane","GO:0004888//transmembrane signaling receptor activity","GO:0050853//B cell receptor signaling pathway;GO:0007165//signal transduction;GO:0045577//regulation of B cell differentiation;GO:0050861//positive regulation of B cell receptor signaling pathway;GO:0035556//intracellular signal transduction;GO:0001819//positive regulation of cytokine production;GO:0006954//inflammatory response;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0043312//neutrophil degranulation;GO:0030183//B cell differentiation","K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K02927//large subunit ribosomal protein L40e;K15696//RING finger protein 113B;K17985//activating molecule in BECN1-regulated autophagy protein 1","NP_666017.1//NFAT activation molecule 1 isoform 1 precursor [Homo sapiens];NP_001305252.1//NFAT activation molecule 1 isoform 2 precursor [Homo sapiens]","6;1//3"]
[1582,3950,0.78,0.99,0.343954401217361,0.379909520256719,"*",0.237164,"CYP8B1","GO:0031090//organelle membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0020037//heme binding;GO:0033778//7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity;GO:0005506//iron ion binding;GO:0008397//sterol 12-alpha-hydroxylase activity;GO:0019825//oxygen binding","GO:0016125//sterol metabolic process;GO:0006699//bile acid biosynthetic process","K07431//sterol 12-alpha-hydroxylase [EC:1.14.18.8 1.14.13.96]","NP_004382.2//7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase [Homo sapiens]","2//1"]
[6232,375,1425.41,1806.29,0.341652585436781,{"v":3.51101887197232e-41,"d":"3.51E-41"},"*",{"v":6.3521E-43,"d":"6.35E-43"},"RPS27","GO:0005840//ribosome","GO:0003735//structural constituent of ribosome","GO:0006412//translation","K02978//small subunit ribosomal protein S27e","XP_004619237.1//PREDICTED: 40S ribosomal protein S27 [Sorex araneus];XP_017707282.1//PREDICTED: 40S ribosomal protein S27-like [Rhinopithecus bieti]","1//3;5"]
[100507507,1741,4.17,5.28,0.34049054591379,0.174426549019608,"*",0.090773,"LOC100507507","NA","NA","NA","NA","XP_008972238.1//PREDICTED: uncharacterized protein LOC100976922 [Pan paniscus]","2//1"]
[8178,4077,2.9,3.67,0.339727162828278,0.0647648175007149,"*",0.0283564,"ELL","GO:0005654//nucleoplasm;GO:0008023//transcription elongation factor complex;GO:0035327//transcriptionally active chromatin;GO:0016607//nuclear speck;GO:0035363//histone locus body;GO:0015030//Cajal body","GO:0019902//phosphatase binding;GO:0003746//translation elongation factor activity","GO:0045945//positive regulation of transcription from RNA polymerase III promoter;GO:0042795//snRNA transcription from RNA polymerase II promoter;GO:0001701//in utero embryonic development;GO:0006366//transcription from RNA polymerase II promoter;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0032786//positive regulation of DNA-templated transcription, elongation;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0010923//negative regulation of phosphatase activity;GO:0042796//snRNA transcription from RNA polymerase III promoter","K15183//RNA polymerase II elongation factor ELL","NP_006523.1//RNA polymerase II elongation factor ELL [Homo sapiens]","3//A2MP1"]
[8892,1557,41.96,53.02,0.337521992289991,{"v":2.81578565517241e-06,"d":"2.82E-06"},"*",{"v":5.00968e-07,"d":"5.01E-07"},"EIF2B2","GO:0005851//eukaryotic translation initiation factor 2B complex;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0003743//translation initiation factor activity;GO:0005524//ATP binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005525//GTP binding","GO:0042552//myelination;GO:0051716//cellular response to stimulus;GO:0043434//response to peptide hormone;GO:0009408//response to heat;GO:0001541//ovarian follicle development;GO:0007417//central nervous system development;GO:0006413//translational initiation;GO:0065009//regulation of molecular function;GO:0006446//regulation of translational initiation;GO:0014003//oligodendrocyte development;GO:0009749//response to glucose","K03754//translation initiation factor eIF-2B subunit beta","NP_055054.1//translation initiation factor eIF-2B subunit beta [Homo sapiens]","3//A2MP1"]
[51458,1952,3.5,4.42,0.336691447559103,0.142817238798155,"*",0.0717126,"RHCG","GO:0070062//extracellular exosome;GO:0016323//basolateral plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016324//apical plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0005886//plasma membrane","GO:0008519//ammonium transmembrane transporter activity;GO:0042802//identical protein binding;GO:0030506//ankyrin binding","GO:0015695//organic cation transport;GO:0042592//homeostatic process;GO:0006885//regulation of pH;GO:0006873//cellular ion homeostasis;GO:0015696//ammonium transport;GO:0015837//amine transport;GO:0070634//transepithelial ammonium transport;GO:0072488//ammonium transmembrane transport;GO:0030855//epithelial cell differentiation","K06580//ammonium transporter Rh","NP_057405.1//ammonium transporter Rh type C [Homo sapiens]","1//3;2//1"]
[122704,1142,33.89,42.78,0.33607684568105,0.000428761858188825,"*",1.114448E-4,"MRPL52","GO:0005762//mitochondrial large ribosomal subunit;GO:0005743//mitochondrial inner membrane","GO:0003735//structural constituent of ribosome","GO:0032543//mitochondrial translation;GO:0006412//translation;GO:0070126//mitochondrial translational termination;GO:0070125//mitochondrial translational elongation","K17433//large subunit ribosomal protein L52","XP_009209406.2//39S ribosomal protein L52, mitochondrial isoform X1 [Papio anubis];CAD66556.1//unnamed protein product, partial [Homo sapiens];NP_851824.1//39S ribosomal protein L52, mitochondrial isoform e [Homo sapiens];NP_001305799.1//39S ribosomal protein L52, mitochondrial isoform f [Homo sapiens]","1//3;2//1"]
[3704,1182,45.59,57.49,0.334593621548739,{"v":1.04122511361442E-5,"d":"1.04E-05"},"*",{"v":2.02522e-06,"d":"2.03E-06"},"ITPA","GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0035870//dITP diphosphatase activity;GO:0042802//identical protein binding;GO:0035529//NADH pyrophosphatase activity;GO:0036220//ITP diphosphatase activity;GO:0047429//nucleoside-triphosphate diphosphatase activity;GO:0036222//XTP diphosphatase activity;GO:0046872//metal ion binding;GO:0000166//nucleotide binding","GO:0009143//nucleoside triphosphate catabolic process;GO:0051276//chromosome organization;GO:0009204//deoxyribonucleoside triphosphate catabolic process;GO:0006195//purine nucleotide catabolic process;GO:0006193//ITP catabolic process;GO:0009117//nucleotide metabolic process","K01519//inosine triphosphate pyrophosphatase [EC:3.6.1.-]","NP_001254552.1//inosine triphosphate pyrophosphatase isoform c [Homo sapiens];NP_852470.1//inosine triphosphate pyrophosphatase isoform b [Homo sapiens];NP_258412.1//inosine triphosphate pyrophosphatase isoform a [Homo sapiens];AAG43165.1//brain my049 protein [Homo sapiens];NP_001311169.1//inosine triphosphate pyrophosphatase isoform e [Homo sapiens]","1//3;3//A2MP1"]
[100463482,1395,837.19,1054.54,0.33298683514678,{"v":4.28776954851485e-95,"d":"4.29E-95"},"*",{"v":2.71106e-97,"d":"2.71E-97"},"MTRNR2L6","NA","NA","NA","NA","NA","2//1"]
[23732,8217,0.54,0.68,0.332575339086871,0.345844182718086,"*",0.209966,"FRRS1L","GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0045202//synapse;GO:0005886//plasma membrane","NA","GO:1900449//regulation of glutamate receptor signaling pathway","K17985//activating molecule in BECN1-regulated autophagy protein 1;K21111//band 4.1-like protein 4B;K03843//alpha-1,3/alpha-1,6-mannosyltransferase [EC:2.4.1.132 2.4.1.257]","NP_055149.2//DOMON domain-containing protein FRRS1L [Homo sapiens]","3//A2MP1"]
[53407,2153,8.23,10.36,0.332059667264928,0.0502851602660754,"*",0.0212958,"STX18","GO:0005783//endoplasmic reticulum;GO:0005622//intracellular;GO:0031201//SNARE complex;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0000139//Golgi membrane","GO:0005484//SNAP receptor activity;GO:0019904//protein domain specific binding","GO:1903358//regulation of Golgi organization;GO:0090158//endoplasmic reticulum membrane organization;GO:1902953//positive regulation of ER to Golgi vesicle-mediated transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:1902117//positive regulation of organelle assembly;GO:0016192//vesicle-mediated transport;GO:0006886//intracellular protein transport;GO:0006888//ER to Golgi vesicle-mediated transport","K08492//syntaxin 18","AAV38937.1//syntaxin 18 [Homo sapiens];NP_001333210.1//syntaxin-18 isoform 2 [Homo sapiens];NP_058626.1//syntaxin-18 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[92691,3477,0.7,0.88,0.330148601692331,0.475751343245228,"*",0.324514,"TMEM169","GO:0016021//integral component of membrane","NA","NA","K22069//LYR motif-containing protein 4;K12581//CCR4-NOT transcription complex subunit 7/8","NP_612399.1//transmembrane protein 169 [Homo sapiens]","1//3;3//A2MP1"]
[1186,4236,29.57,37.16,0.329616258262328,{"v":6.94473965924984e-11,"d":"6.94E-11"},"*",{"v":6.83866e-12,"d":"6.84E-12"},"CLCN7","GO:0016020//membrane;GO:0005765//lysosomal membrane;GO:0031410//cytoplasmic vesicle;GO:0016021//integral component of membrane","GO:0005524//ATP binding;GO:0005247//voltage-gated chloride channel activity;GO:0005254//chloride channel activity;GO:0015297//antiporter activity","GO:0006810//transport;GO:0009268//response to pH;GO:0034220//ion transmembrane transport;GO:1902476//chloride transmembrane transport","K05016//chloride channel 7","NP_001278.1//H(+)/Cl(-) exchange transporter 7 isoform a [Homo sapiens];NP_001107803.1//H(+)/Cl(-) exchange transporter 7 isoform b [Homo sapiens]","2//1;5"]
[126070,4181,0.39,0.49,0.32930762525296,0.612688965366876,"*",0.457388,"ZNF440","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_018872019.1//PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 69-like [Gorilla gorilla gorilla]","2//1"]
[64978,1614,74.82,93.96,0.328622747461371,{"v":2.66417380214541e-10,"d":"2.66E-10"},"*",{"v":2.7986E-11,"d":"2.80E-11"},"MRPL38","GO:0005762//mitochondrial large ribosomal subunit;GO:0005743//mitochondrial inner membrane","NA","GO:0070126//mitochondrial translational termination;GO:0070125//mitochondrial translational elongation","K17419//large subunit ribosomal protein L38","NP_115867.2//39S ribosomal protein L38, mitochondrial [Homo sapiens]","3//A2MP1"]
[391322,943,2.08,2.61,0.327466278428792,0.83223325666897,"*",0.753876,"LOC391322","NA","NA","NA","K10028//D-dopachrome decarboxylase [EC:4.1.1.84]","XP_001170336.2//PREDICTED: D-dopachrome decarboxylase [Pan troglodytes]","1//3;2//1"]
[516,594,356.9,447.51,0.326400019625079,{"v":2.25010905e-16,"d":"2.25E-16"},"*",{"v":1.419876E-17,"d":"1.42E-17"},"ATP5MC1","GO:0000276//mitochondrial proton-transporting ATP synthase complex, coupling factor F(o);GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0045263//proton-transporting ATP synthase complex, coupling factor F(o);GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion","GO:0008289//lipid binding;GO:0015078//hydrogen ion transmembrane transporter activity;GO:0005215//transporter activity;GO:0046933//proton-transporting ATP synthase activity, rotational mechanism","GO:0015986//ATP synthesis coupled proton transport;GO:0006754//ATP biosynthetic process;GO:0042407//cristae formation;GO:0015991//ATP hydrolysis coupled proton transport;GO:0042776//mitochondrial ATP synthesis coupled proton transport","K02128//F-type H+-transporting ATPase subunit c","NP_005166.1//ATP synthase F(0) complex subunit C1, mitochondrial precursor [Homo sapiens]","1//3;2//1"]
[59274,3068,16.99,21.29,0.325490097268074,{"v":5.84457127026264e-05,"d":"5.84E-05"},"*",{"v":1.295582E-5,"d":"1.30E-05"},"TLNRD1","GO:0001725//stress fiber","GO:0003779//actin binding","NA","K06271//talin","NP_072088.1//mesoderm development candidate 1 [Homo sapiens]","2//1"]
[7297,4262,14.91,18.68,0.32521419742622,{"v":7.55652887701945e-06,"d":"7.56E-06"},"*",{"v":1.434766e-06,"d":"1.43E-06"},"TYK2","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0031702//type 1 angiotensin receptor binding;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005524//ATP binding;GO:0005131//growth hormone receptor binding","GO:0060337//type I interferon signaling pathway;GO:0016477//cell migration;GO:0038083//peptidyl-tyrosine autophosphorylation;GO:0030154//cell differentiation;GO:0042127//regulation of cell proliferation;GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0060338//regulation of type I interferon-mediated signaling pathway;GO:0045087//innate immune response;GO:0035722//interleukin-12-mediated signaling pathway","K11219//non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]","NP_003322.3//non-receptor tyrosine-protein kinase TYK2 [Homo sapiens]",4]
[145553,760,10.81,13.53,0.323795316241887,0.154663900502882,"*",0.0789392,"MDP1","GO:0070062//extracellular exosome","GO:0046872//metal ion binding;GO:0004725//protein tyrosine phosphatase activity;GO:0016791//phosphatase activity","NA","K17619//magnesium-dependent phosphatase 1 [EC:3.1.3.48 3.1.3.-]","NP_612485.2//magnesium-dependent phosphatase 1 isoform 1 [Homo sapiens];NP_001186750.1//magnesium-dependent phosphatase 1 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[2647,590,60.51,75.7,0.323119715538976,0.00187300067685775,"*",0.000552262,"BLOC1S1","GO:0005759//mitochondrial matrix;GO:0005765//lysosomal membrane;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0099078//BORC complex;GO:0031083//BLOC-1 complex;GO:1904115//axon cytoplasm;GO:0005758//mitochondrial intermembrane space;GO:0005829//cytosol;GO:0005769//early endosome","NA","GO:0016197//endosomal transport;GO:0060155//platelet dense granule organization;GO:0018394//peptidyl-lysine acetylation;GO:0009060//aerobic respiration;GO:0048490//anterograde synaptic vesicle transport;GO:0031175//neuron projection development;GO:0008089//anterograde axonal transport;GO:0032418//lysosome localization;GO:0032438//melanosome organization","K20185//biogenesis of lysosome-related organelles complex 1 subunit 1","XP_008001755.1//PREDICTED: biogenesis of lysosome-related organelles complex 1 subunit 1 [Chlorocebus sabaeus]","3//A2MP1"]
[3780,2662,0.48,0.6,0.321928094887362,0.629890858297079,"*",0.507572,"KCNN1","NA","NA","NA","K04942//potassium intermediate/small conductance calcium-activated channel subfamily N member 1","XP_005259963.1//PREDICTED: small conductance calcium-activated potassium channel protein 1 isoform X2 [Homo sapiens]",4]
[25890,5756,0.04,0.05,0.321928094887362,0.78158613986014,"*",0.685686,"ABI3BP","GO:0031012//extracellular matrix;GO:0005615//extracellular space;GO:0005614//interstitial matrix;GO:0005576//extracellular region","GO:0005518//collagen binding;GO:0008201//heparin binding","GO:0030198//extracellular matrix organization;GO:0010811//positive regulation of cell-substrate adhesion","K10955//mucin-2;K08592//sentrin-specific protease 1 [EC:3.4.22.68]","NP_056244.2//target of Nesh-SH3 isoform 5 precursor [Homo sapiens];NP_001336259.1//target of Nesh-SH3 isoform 2 precursor [Homo sapiens];NP_001336260.1//target of Nesh-SH3 isoform 3 precursor [Homo sapiens];NP_001336258.1//target of Nesh-SH3 isoform 1 precursor [Homo sapiens];NP_001336261.1//target of Nesh-SH3 isoform 4 precursor [Homo sapiens]","1//3;3//A2MP1"]
[57414,1720,83.53,104.38,0.321478963915631,{"v":1.74981541086749e-08,"d":"1.75E-08"},"*",{"v":2.29818E-9,"d":"2.30E-09"},"RHBDD2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm;GO:0000139//Golgi membrane","GO:0004252//serine-type endopeptidase activity","NA","K09652//rhomboid domain-containing protein 2","XP_016814284.1//PREDICTED: rhomboid domain-containing protein 2 isoform X6 [Pan troglodytes];EAW71773.1//rhomboid domain containing 2, isoform CRA_a [Homo sapiens];NP_001333117.1//rhomboid domain-containing protein 2 isoform c [Homo sapiens];NP_001333118.1//rhomboid domain-containing protein 2 isoform d [Homo sapiens]","1//3;2//1"]
[23523,7197,10.84,13.53,0.319797082622665,{"v":1.44329857479735e-06,"d":"1.44E-06"},"*",{"v":2.45218e-07,"d":"2.45E-07"},"CABIN1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016235//aggresome","GO:0004864//protein phosphatase inhibitor activity","GO:0016569//covalent chromatin modification;GO:0006336//DNA replication-independent nucleosome assembly;GO:0007166//cell surface receptor signaling pathway","K17613//calcineurin-binding protein cabin-1","NP_001188358.1//calcineurin-binding protein cabin-1 isoform b [Homo sapiens];NP_036427.1//calcineurin-binding protein cabin-1 isoform a [Homo sapiens]","1//3;3//A2MP1"]
[843,5317,2.88,3.59,0.317915032380739,0.0354752352329361,"*",0.01434866,"CASP10","GO:0031265//CD95 death-inducing signaling complex;GO:0005829//cytosol;GO:0097342//ripoptosome","GO:0097199//cysteine-type endopeptidase activity involved in apoptotic signaling pathway;GO:0004197//cysteine-type endopeptidase activity;GO:0031625//ubiquitin protein ligase binding;GO:0035877//death effector domain binding;GO:0097200//cysteine-type endopeptidase activity involved in execution phase of apoptosis","GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0097194//execution phase of apoptosis;GO:0097190//apoptotic signaling pathway;GO:0007166//cell surface receptor signaling pathway;GO:0042981//regulation of apoptotic process;GO:0006915//apoptotic process","K04400//caspase 10 [EC:3.4.22.63]","NP_116756.2//caspase-10 isoform 2 preproprotein [Homo sapiens];NP_001293012.1//caspase-10 isoform 7 [Homo sapiens];XP_006712859.1//PREDICTED: caspase-10 isoform X2 [Homo sapiens];NP_001193453.1//caspase-10 isoform 6 preproprotein [Homo sapiens];NP_001221.2//caspase-10 isoform 3 preproprotein [Homo sapiens];NP_116759.2//caspase-10 isoform 1 preproprotein [Homo sapiens];NP_001193471.1//caspase-10 isoform 5 preproprotein [Homo sapiens]","4;1//3;3//A2MP1"]
[54663,1350,36.88,45.96,0.317540142216775,0.00027327236108325,"*",{"v":6.8224e-05,"d":"6.82E-05"},"WDR74","GO:0005634//nucleus;GO:0005730//nucleolus;GO:0030687//preribosome, large subunit precursor","NA","GO:0042273//ribosomal large subunit biogenesis","K14841//ribosome biogenesis protein NSA1","NP_060563.2//WD repeat-containing protein 74 isoform 1 [Homo sapiens];NP_001294906.1//WD repeat-containing protein 74 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[79574,2329,0.61,0.76,0.317190175880699,0.582918271029638,"*",0.426004,"EPS8L3","GO:0005737//cytoplasm","NA","GO:0042634//regulation of hair cycle","K17277//epidermal growth factor receptor kinase substrate 8","NP_078802.2//epidermal growth factor receptor kinase substrate 8-like protein 3 isoform c [Homo sapiens];XP_016857818.1//PREDICTED: epidermal growth factor receptor kinase substrate 8-like protein 3 isoform X6 [Homo sapiens];NP_620641.1//epidermal growth factor receptor kinase substrate 8-like protein 3 isoform a [Homo sapiens];NP_573444.2//epidermal growth factor receptor kinase substrate 8-like protein 3 isoform b [Homo sapiens]","1//3;3//A2MP1;2//1"]
[3459,2138,12.07,15.03,0.316419333161343,0.00887724364569962,"*",0.0030304,"IFNGR1","GO:0043231//intracellular membrane-bounded organelle;GO:0030425//dendrite;GO:0005783//endoplasmic reticulum;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0031982//vesicle;GO:0014069//postsynaptic density;GO:0005886//plasma membrane","GO:0004906//interferon-gamma receptor activity;GO:0019955//cytokine binding;GO:0004896//cytokine receptor activity","GO:0060333//interferon-gamma-mediated signaling pathway;GO:0007165//signal transduction;GO:0060334//regulation of interferon-gamma-mediated signaling pathway;GO:0051607//defense response to virus;GO:0019221//cytokine-mediated signaling pathway;GO:0009615//response to virus","K05132//interferon gamma receptor 1","NP_000407.1//interferon gamma receptor 1 precursor [Homo sapiens]","2//1"]
[79415,2255,29.21,36.35,0.315493005977778,{"v":6.4100298816933e-05,"d":"6.41E-05"},"*",{"v":1.431362e-05,"d":"1.43E-05"},"C17orf62","NA","NA","NA","K12740//NK-tumor recognition protein;K13172//serine/arginine repetitive matrix protein 2","BAC03465.1//FLJ00406 protein, partial [Homo sapiens]","1//3;3//A2MP1;2//1"]
[29880,1227,11.17,13.89,0.314417413498078,0.0743533768627451,"*",0.0332342,"ALG5","GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0004581//dolichyl-phosphate beta-glucosyltransferase activity;GO:0004576//oligosaccharyl transferase activity","GO:0006486//protein glycosylation;GO:0018279//protein N-linked glycosylation via asparagine;GO:0007368//determination of left/right symmetry;GO:0006487//protein N-linked glycosylation","K00729//dolichyl-phosphate beta-glucosyltransferase [EC:2.4.1.117]","XP_007958363.1//PREDICTED: dolichyl-phosphate beta-glucosyltransferase isoform X1 [Chlorocebus sabaeus]","1//3;4"]
[133957,1437,14.67,18.22,0.312654088128661,0.0222826258064516,"*",0.0084756,"CCDC127","NA","NA","NA","NA","XP_001139848.2//PREDICTED: coiled-coil domain-containing protein 127 [Pan troglodytes]","2//1"]
[11151,1832,1.37,1.7,0.311358853177175,0.491447801400382,"*",0.338328,"CORO1A","GO:0031252//cell leading edge;GO:0016020//membrane;GO:0005737//cytoplasm;GO:0045335//phagocytic vesicle;GO:0030864//cortical actin cytoskeleton;GO:0005911//cell-cell junction;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0005886//plasma membrane;GO:0005769//early endosome;GO:0030424//axon;GO:0070062//extracellular exosome;GO:0030670//phagocytic vesicle membrane;GO:0001772//immunological synapse;GO:0030027//lamellipodium;GO:0001891//phagocytic cup;GO:0005884//actin filament;GO:0043234//protein complex","GO:0043548//phosphatidylinositol 3-kinase binding;GO:0051015//actin filament binding;GO:0003723//RNA binding;GO:0042802//identical protein binding;GO:0008092//cytoskeletal protein binding;GO:0003785//actin monomer binding;GO:0042803//protein homodimerization activity;GO:0032036//myosin heavy chain binding;GO:0003779//actin binding;GO:0008022//protein C-terminus binding","GO:0030833//regulation of actin filament polymerization;GO:0032796//uropod organization;GO:0061502//early endosome to recycling endosome transport;GO:0030335//positive regulation of cell migration;GO:0051279//regulation of release of sequestered calcium ion into cytosol;GO:0042102//positive regulation of T cell proliferation;GO:0048873//homeostasis of number of cells within a tissue;GO:0032956//regulation of actin cytoskeleton organization;GO:0051126//negative regulation of actin nucleation;GO:0043320//natural killer cell degranulation;GO:0007015//actin filament organization;GO:0001845//phagolysosome assembly;GO:0071353//cellular response to interleukin-4;GO:0045087//innate immune response;GO:0006909//phagocytosis;GO:0030036//actin cytoskeleton organization;GO:0031339//negative regulation of vesicle fusion;GO:0030595//leukocyte chemotaxis;GO:0043524//negative regulation of neuron apoptotic process;GO:0006816//calcium ion transport;GO:0031589//cell-substrate adhesion;GO:0008360//regulation of cell shape;GO:0043029//T cell homeostasis;GO:0006928//movement of cell or subcellular component;GO:0038180//nerve growth factor signaling pathway;GO:0050918//positive chemotaxis","K13882//coronin-1A","XP_017374636.1//PREDICTED: coronin-1A isoform X1 [Cebus capucinus imitator];XP_008959819.1//PREDICTED: coronin-1A isoform X1 [Pan paniscus]","3//A2MP1;2//1"]
[2014,645,559.02,693.17,0.310309317694159,{"v":2.99976532495755e-24,"d":"3.00E-24"},"*",{"v":1.106086E-25,"d":"1.11E-25"},"EMP3","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","NA","GO:0032060//bleb assembly;GO:0008219//cell death;GO:0016049//cell growth;GO:0008285//negative regulation of cell proliferation","K19289//peripheral myelin protein 22","NP_001416.1//epithelial membrane protein 3 [Homo sapiens]","1//3;2//1"]
[51399,1286,16.72,20.72,0.309449155605671,0.0227868664676943,"*",0.00869878,"TRAPPC4","GO:0030425//dendrite;GO:0005783//endoplasmic reticulum;GO:0008021//synaptic vesicle;GO:0030008//TRAPP complex;GO:0000139//Golgi membrane;GO:0005795//Golgi stack;GO:0005829//cytosol;GO:0045202//synapse","GO:0017112//Rab guanyl-nucleotide exchange factor activity","GO:0006810//transport;GO:0016358//dendrite development;GO:0048208//COPII vesicle coating;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0016192//vesicle-mediated transport;GO:0061024//membrane organization","K20303//trafficking protein particle complex subunit 4","XP_008511651.1//PREDICTED: trafficking protein particle complex subunit 4 [Equus przewalskii];NP_001305418.1//trafficking protein particle complex subunit 4 isoform 4 [Homo sapiens];NP_001305423.1//trafficking protein particle complex subunit 4 isoform 7 [Homo sapiens];NP_001305419.1//trafficking protein particle complex subunit 4 isoform 5 [Homo sapiens]","1//3;5"]
[83743,2456,52.58,65.12,0.308586557648201,{"v":9.04701002345059E-10,"d":"9.05E-10"},"*",{"v":1.014348E-10,"d":"1.01E-10"},"GRWD1","GO:0005634//nucleus;GO:0005730//nucleolus;GO:0043234//protein complex;GO:0005829//cytosol;GO:0005694//chromosome","GO:0042393//histone binding;GO:0003688//DNA replication origin binding;GO:0003723//RNA binding;GO:0003682//chromatin binding","GO:0006260//DNA replication;GO:0006334//nucleosome assembly;GO:0006337//nucleosome disassembly","K14848//ribosome assembly protein RRB1","NP_113673.3//glutamate-rich WD repeat-containing protein 1 [Homo sapiens]","3//A2MP1"]
[25816,2147,5.57,6.89,0.30682665536426,0.0858303562380038,"*",0.0391916,"TNFAIP8","GO:0005737//cytoplasm","GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process","GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0042981//regulation of apoptotic process","K12471//epsin","NP_001071122.1//tumor necrosis factor alpha-induced protein 8 isoform b [Homo sapiens];XP_010337813.1//PREDICTED: tumor necrosis factor alpha-induced protein 8 isoform X1 [Saimiri boliviensis boliviensis];NP_001273743.1//tumor necrosis factor alpha-induced protein 8 isoform c [Homo sapiens];XP_021561633.1//tumor necrosis factor alpha-induced protein 8 isoform X2 [Carlito syrichta]","1//3;3//A2MP1;2//1"]
[55621,2118,21.36,26.41,0.306172654479539,0.000759572674157303,"*",0.000207368,"TRMT1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion","GO:0004809//tRNA (guanine-N2-)-methyltransferase activity;GO:0003723//RNA binding;GO:0046872//metal ion binding;GO:0000049//tRNA binding","GO:0002940//tRNA N2-guanine methylation;GO:0006400//tRNA modification","K00555//tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase [EC:2.1.1.215 2.1.1.216]","NP_001136026.1//tRNA (guanine(26)-N(2))-dimethyltransferase isoform 2 [Homo sapiens];NP_060192.1//tRNA (guanine(26)-N(2))-dimethyltransferase isoform 1 [Homo sapiens]","4;1//3;3//A2MP1;2//1"]
[10211,2025,55.99,69.19,0.305394360803594,{"v":7.07899657517659E-9,"d":"7.08E-09"},"*",{"v":8.78338e-10,"d":"8.78E-10"},"FLOT1","GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0044291//cell-cell contact zone;GO:0001931//uropod;GO:0042470//melanosome;GO:0034451//centriolar satellite;GO:0030864//cortical actin cytoskeleton;GO:0005901//caveola;GO:0005913//cell-cell adherens junction;GO:0008180//COP9 signalosome;GO:0005911//cell-cell junction;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005769//early endosome;GO:0070062//extracellular exosome;GO:0005765//lysosomal membrane;GO:0005815//microtubule organizing center;GO:0005925//focal adhesion;GO:0030027//lamellipodium;GO:0005768//endosome;GO:0045121//membrane raft;GO:0042383//sarcolemma;GO:0016600//flotillin complex","GO:0002020//protease binding;GO:0046982//protein heterodimerization activity;GO:0035255//ionotropic glutamate receptor binding","GO:0032226//positive regulation of synaptic transmission, dopaminergic;GO:0034976//response to endoplasmic reticulum stress;GO:0051260//protein homooligomerization;GO:0045807//positive regulation of endocytosis;GO:0001819//positive regulation of cytokine production;GO:0032092//positive regulation of protein binding;GO:1903044//protein localization to membrane raft;GO:1901890//positive regulation of cell junction assembly;GO:0001934//positive regulation of protein phosphorylation;GO:0001765//membrane raft assembly;GO:1901741//positive regulation of myoblast fusion;GO:0034116//positive regulation of heterotypic cell-cell adhesion;GO:0072659//protein localization to plasma membrane;GO:0032728//positive regulation of interferon-beta production;GO:0070528//protein kinase C signaling;GO:0071360//cellular response to exogenous dsRNA;GO:0034141//positive regulation of toll-like receptor 3 signaling pathway;GO:0044854//plasma membrane raft assembly;GO:0007409//axonogenesis;GO:0033227//dsRNA transport;GO:2000049//positive regulation of cell-cell adhesion mediated by cadherin;GO:0022617//extracellular matrix disassembly;GO:0048643//positive regulation of skeletal muscle tissue development;GO:0035023//regulation of Rho protein signal transduction;GO:0002090//regulation of receptor internalization;GO:0050821//protein stabilization;GO:0060355//positive regulation of cell adhesion molecule production","K07192//flotillin","NP_001305804.1//flotillin-1 isoform 2 [Homo sapiens];NP_005794.1//flotillin-1 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[55716,2294,3.53,4.36,0.304659951505746,0.271485675402699,"*",0.1561544,"LMBR1L","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004872//receptor activity","GO:0006898//receptor-mediated endocytosis","NA","NP_060583.2//protein LMBR1L isoform 1 [Homo sapiens];NP_001339090.1//protein LMBR1L isoform 4 [Homo sapiens];XP_016875117.1//PREDICTED: protein LMBR1L isoform X4 [Homo sapiens];NP_001339097.1//protein LMBR1L isoform 9 [Homo sapiens];NP_001287679.1//protein LMBR1L isoform 2 [Homo sapiens];NP_001339091.1//protein LMBR1L isoform 5 [Homo sapiens];NP_001287680.1//protein LMBR1L isoform 3 [Homo sapiens];EDL04155.1//limb region 1 like, isoform CRA_b, partial [Mus musculus]","1//3;3//A2MP1"]
[487,3569,0.64,0.79,0.303780748177103,0.641514756014806,"*",0.520794,"ATP2A1","GO:0016021//integral component of membrane","GO:0005524//ATP binding;GO:0005388//calcium-transporting ATPase activity","NA","K05853//Ca2+ transporting ATPase, sarcoplasmic/endoplasmic reticulum [EC:3.6.3.8]","XP_014981340.1//PREDICTED: sarcoplasmic/endoplasmic reticulum calcium ATPase 1 isoform X1 [Macaca mulatta];EDL17360.1//ATPase, Ca++ transporting, cardiac muscle, fast twitch 1, isoform CRA_d, partial [Mus musculus];XP_004586901.1//PREDICTED: sarcoplasmic/endoplasmic reticulum calcium ATPase 1 isoform X1 [Ochotona princeps]","1//3;4;3//A2MP1"]
[230,1665,5.77,7.12,0.303305922320915,0.162408812606474,"*",0.083553,"ALDOC","GO:0070062//extracellular exosome;GO:0005739//mitochondrion","GO:0008092//cytoskeletal protein binding;GO:0004332//fructose-bisphosphate aldolase activity","GO:0006096//glycolytic process;GO:0030388//fructose 1,6-bisphosphate metabolic process;GO:0030855//epithelial cell differentiation","K01623//fructose-bisphosphate aldolase, class I [EC:4.1.2.13]","XP_012304797.1//fructose-bisphosphate aldolase C isoform X1 [Aotus nancymaae]","2//1"]
[1072,1260,1621.29,1999.1,0.302208472442231,{"v":3.36003791701492e-135,"d":"3.36E-135"},"*",{"v":1.409306e-137,"d":"1.41E-137"},"CFL1","NA","NA","NA","K05765//cofilin","BAB32114.1//unnamed protein product [Mus musculus]","2//1"]
[6788,2828,5.53,6.81,0.300375317777364,0.155117811096142,"*",0.0792874,"STK3","GO:0005634//nucleus;GO:0043234//protein complex;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0000287//magnesium ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0042802//identical protein binding;GO:0043539//protein serine/threonine kinase activator activity;GO:0046983//protein dimerization activity","GO:0023014//signal transduction by protein phosphorylation;GO:0046330//positive regulation of JNK cascade;GO:0001841//neural tube formation;GO:0097284//hepatocyte apoptotic process;GO:0051897//positive regulation of protein kinase B signaling;GO:0007346//regulation of mitotic cell cycle;GO:0060800//regulation of cell differentiation involved in embryonic placenta development;GO:0035329//hippo signaling;GO:0035556//intracellular signal transduction;GO:0032092//positive regulation of protein binding;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0046621//negative regulation of organ growth;GO:0003157//endocardium development;GO:0031098//stress-activated protein kinase signaling cascade;GO:0008285//negative regulation of cell proliferation;GO:0060215//primitive hemopoiesis;GO:0007165//signal transduction;GO:0032147//activation of protein kinase activity;GO:0006468//protein phosphorylation;GO:0045600//positive regulation of fat cell differentiation;GO:0007417//central nervous system development;GO:0006915//apoptotic process;GO:1902043//positive regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0060706//cell differentiation involved in embryonic placenta development;GO:0042981//regulation of apoptotic process;GO:0050821//protein stabilization","K04412//serine/threonine kinase 3","XP_007999376.1//PREDICTED: serine/threonine-protein kinase 3 isoform X1 [Chlorocebus sabaeus];XP_011515550.2//PREDICTED: serine/threonine-protein kinase 3 isoform X2 [Homo sapiens];NP_001243242.1//serine/threonine-protein kinase 3 isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[56917,2011,22.01,27.09,0.299601248310457,0.00355096364072815,"*",1.11126E-3,"MEIS3","GO:0005634//nucleus","GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0043565//sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0051897//positive regulation of protein kinase B signaling;GO:0006355//regulation of transcription, DNA-templated;GO:2001234//negative regulation of apoptotic signaling pathway","K16671//homeobox protein Meis3","NP_001333077.1//homeobox protein Meis3 isoform 4 [Homo sapiens];NP_001287988.1//homeobox protein Meis3 isoform 3 [Homo sapiens];NP_064545.1//homeobox protein Meis3 isoform 1 [Homo sapiens];NP_001009813.1//homeobox protein Meis3 isoform 2 [Homo sapiens]","1//3;2//1"]
[252884,3658,0.26,0.32,0.299560281858908,0.647293726293103,"*",0.526458,"ZNF396","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity;GO:0003700//DNA binding transcription factor activity;GO:0042803//protein homodimerization activity","GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09229//KRAB and SCAN domains-containing zinc finger protein;K09230//SCAN domain-containing zinc finger protein","XP_003779011.1//PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 396 [Pongo abelii];NP_001309220.1//zinc finger protein 396 isoform 3 [Homo sapiens];XP_004623766.2//PREDICTED: zinc finger protein 345 isoform X1 [Octodon degus]","1//3;2//1"]
[970,2259,28.68,35.27,0.298396551724347,0.20897925203252,"*",0.11264,"CD70","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005164//tumor necrosis factor receptor binding;GO:0002020//protease binding;GO:0005125//cytokine activity;GO:0005102//receptor binding","GO:0007165//signal transduction;GO:0097191//extrinsic apoptotic signaling pathway;GO:0008283//cell proliferation;GO:0006955//immune response;GO:0007267//cell-cell signaling;GO:0033209//tumor necrosis factor-mediated signaling pathway","K05470//tumor necrosis factor ligand superfamily member 7","NP_001317261.1//CD70 antigen isoform 2 [Homo sapiens];XP_001088935.2//PREDICTED: CD70 antigen [Macaca mulatta]","4;1//3"]
[8904,2017,79.11,97.28,0.298283156857869,{"v":2.0963798573156e-10,"d":"2.10E-10"},"*",{"v":2.17066E-11,"d":"2.17E-11"},"CPNE1","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0005737//cytoplasm;GO:0035577//azurophil granule membrane;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0004175//endopeptidase activity;GO:0005544//calcium-dependent phospholipid binding;GO:0051059//NF-kappaB binding;GO:0005509//calcium ion binding;GO:0042803//protein homodimerization activity;GO:0001786//phosphatidylserine binding;GO:0005215//transporter activity","GO:0051897//positive regulation of protein kinase B signaling;GO:0045666//positive regulation of neuron differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0010629//negative regulation of gene expression;GO:0016192//vesicle-mediated transport;GO:0071277//cellular response to calcium ion;GO:1901223//negative regulation of NIK/NF-kappaB signaling;GO:1990138//neuron projection extension;GO:0043312//neutrophil degranulation;GO:1903265//positive regulation of tumor necrosis factor-mediated signaling pathway;GO:0006351//transcription, DNA-templated;GO:0046474//glycerophospholipid biosynthetic process;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043392//negative regulation of DNA binding;GO:0006508//proteolysis;GO:0006629//lipid metabolic process","K16280//E3 ubiquitin-protein ligase RGLG [EC:2.3.2.27];K20493//leucine-rich repeat-containing protein 16","NP_003906.2//copine-1 isoform b [Homo sapiens];XP_017827294.1//PREDICTED: copine-1 isoform X5 [Callithrix jacchus];NP_690902.1//copine-1 isoform a [Homo sapiens];NP_001185792.1//copine-1 isoform c [Homo sapiens]","1//3;2//1;5"]
[93100,1721,9.17,11.27,0.297493876577167,0.0678423572749253,"*",0.029861,"NAPRT","GO:0070062//extracellular exosome;GO:0035578//azurophil granule lumen;GO:0005829//cytosol;GO:0005576//extracellular region","GO:0004516//nicotinate phosphoribosyltransferase activity;GO:0004514//nicotinate-nucleotide diphosphorylase (carboxylating) activity;GO:0016874//ligase activity","GO:0006979//response to oxidative stress;GO:0019358//nicotinate nucleotide salvage;GO:0034356//NAD biosynthesis via nicotinamide riboside salvage pathway;GO:0043312//neutrophil degranulation","K00763//nicotinate phosphoribosyltransferase [EC:6.3.4.21]","NP_001273758.1//nicotinate phosphoribosyltransferase isoform 2 [Homo sapiens];NP_660202.3//nicotinate phosphoribosyltransferase isoform 1 [Homo sapiens]","1//3;5"]
[1201,1868,33.14,40.7,0.296455191932158,{"v":6.60021022147651e-05,"d":"6.60E-05"},"*",{"v":1.477548E-5,"d":"1.48E-05"},"CLN3","GO:0005783//endoplasmic reticulum;GO:0005770//late endosome;GO:0005737//cytoplasm;GO:0000139//Golgi membrane;GO:0005795//Golgi stack;GO:0005901//caveola;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0005776//autophagosome;GO:0005769//early endosome;GO:0005765//lysosomal membrane;GO:0005634//nucleus;GO:0008021//synaptic vesicle;GO:0005764//lysosome;GO:0005802//trans-Golgi network;GO:0043005//neuron projection;GO:0045121//membrane raft;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005794//Golgi apparatus","GO:0051082//unfolded protein binding;GO:0048306//calcium-dependent protein binding","GO:0035752//lysosomal lumen pH elevation;GO:0016477//cell migration;GO:0042987//amyloid precursor protein catabolic process;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0006672//ceramide metabolic process;GO:0097352//autophagosome maturation;GO:0016485//protein processing;GO:0051489//regulation of filopodium assembly;GO:0030036//actin cytoskeleton organization;GO:0006520//cellular amino acid metabolic process;GO:0043524//negative regulation of neuron apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0015809//arginine transport;GO:0042133//neurotransmitter metabolic process;GO:0006865//amino acid transport;GO:0006898//receptor-mediated endocytosis;GO:0006681//galactosylceramide metabolic process;GO:0001508//action potential;GO:0007042//lysosomal lumen acidification;GO:0050885//neuromuscular process controlling balance;GO:0016236//macroautophagy;GO:0001575//globoside metabolic process;GO:0045861//negative regulation of proteolysis;GO:0006678//glucosylceramide metabolic process;GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0001934//positive regulation of protein phosphorylation;GO:0006897//endocytosis;GO:0043086//negative regulation of catalytic activity;GO:0007040//lysosome organization;GO:0006684//sphingomyelin metabolic process;GO:0047496//vesicle transport along microtubule;GO:0072659//protein localization to plasma membrane;GO:0030163//protein catabolic process;GO:0007034//vacuolar transport;GO:0061024//membrane organization;GO:0008306//associative learning","K12389//battenin","NP_000077.1//battenin isoform a [Homo sapiens];XP_011943818.1//PREDICTED: battenin isoform X2 [Cercocebus atys];NP_001273033.1//battenin isoform b [Homo sapiens]","1//3;2//1"]
[51710,2773,0.57,0.7,0.296393002780225,0.593888752977203,"*",0.43707,"ZNF44","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","XP_512401.4//PREDICTED: zinc finger protein 44 isoform X10 [Pan troglodytes];XP_015296246.1//PREDICTED: zinc finger protein 44 isoform X1 [Macaca fascicularis];NP_057348.3//zinc finger protein 44 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[11331,1453,224.75,275.74,0.29498745017844,{"v":5.07287639831697e-21,"d":"5.07E-21"},"*",{"v":2.26428E-22,"d":"2.26E-22"},"PHB2","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0030424//axon;GO:0005634//nucleus;GO:0071944//cell periphery;GO:0016363//nuclear matrix;GO:0005741//mitochondrial outer membrane;GO:0005737//cytoplasm;GO:0009986//cell surface;GO:0043234//protein complex;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0030331//estrogen receptor binding;GO:0008022//protein C-terminus binding;GO:0047485//protein N-terminus binding;GO:0033218//amide binding","GO:0071456//cellular response to hypoxia;GO:0043433//negative regulation of DNA binding transcription factor activity;GO:0000060//protein import into nucleus, translocation;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0031536//positive regulation of exit from mitosis;GO:0033147//negative regulation of intracellular estrogen receptor signaling pathway;GO:0009611//response to wounding;GO:0006851//mitochondrial calcium ion transmembrane transport;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0060744//mammary gland branching involved in thelarche;GO:0043066//negative regulation of apoptotic process;GO:0007005//mitochondrion organization;GO:0060762//regulation of branching involved in mammary gland duct morphogenesis;GO:0071300//cellular response to retinoic acid;GO:0060749//mammary gland alveolus development;GO:0007062//sister chromatid cohesion;GO:1902808//positive regulation of cell cycle G1/S phase transition;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0050821//protein stabilization;GO:0033600//negative regulation of mammary gland epithelial cell proliferation","K17081//prohibitin 2","NP_031557.2//prohibitin-2 [Mus musculus];NP_001254629.1//prohibitin-2 isoform 3 [Homo sapiens]","1//3"]
[5625,2151,1.24,1.52,0.29373120305671,0.673883572794899,"*",0.555762,"PRODH","GO:0005759//mitochondrial matrix;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0004657//proline dehydrogenase activity;GO:0071949//FAD binding","GO:0008631//intrinsic apoptotic signaling pathway in response to oxidative stress;GO:0006562//proline catabolic process;GO:0019470//4-hydroxyproline catabolic process;GO:0010133//proline catabolic process to glutamate;GO:0006560//proline metabolic process;GO:0010942//positive regulation of cell death","K00318//proline dehydrogenase [EC:1.5.-.-]","NP_057419.4//proline dehydrogenase 1, mitochondrial isoform 1 precursor [Homo sapiens]","4;1//3"]
[91074,4405,0.31,0.38,0.29373120305671,0.639663265621379,"*",0.51845,"ANKRD30A","GO:0005634//nucleus","GO:0003677//DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0006355//regulation of transcription, DNA-templated","K17299//POTE ankyrin domain family protein","Q9BXX3.3//RecName: Full=Ankyrin repeat domain-containing protein 30A; AltName: Full=Serologically defined breast cancer antigen NY-BR-1","2//1"]
[100128124,1016,0.4,0.49,0.292781749227846,0.846805230853767,"*",0.771794,"HGC6","NA","NA","NA","K10385//loricrin;K02184//formin 2","NP_001123367.1//uncharacterized protein LOC100128124 [Homo sapiens]","2//1"]
[9454,1424,21.7,26.58,0.292646061944333,0.00878719618732782,"*",2.99526E-3,"HOMER3","GO:0005829//cytosol;GO:0030054//cell junction;GO:0014069//postsynaptic density;GO:0045211//postsynaptic membrane;GO:0045178//basal part of cell","GO:0019904//protein domain specific binding;GO:0008022//protein C-terminus binding;GO:0035256//G-protein coupled glutamate receptor binding;GO:0042802//identical protein binding","GO:0006605//protein targeting;GO:0007216//G-protein coupled glutamate receptor signaling pathway","K15010//homer","NP_001139196.1//homer protein homolog 3 isoform 3 [Homo sapiens];NP_001139193.1//homer protein homolog 3 isoform 2 [Homo sapiens];NP_004829.3//homer protein homolog 3 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[65057,2093,26.83,32.84,0.291607072517284,0.000239486811364789,"*",{"v":5.90996e-05,"d":"5.91E-05"},"ACD","GO:0005654//nucleoplasm;GO:0000784//nuclear chromosome, telomeric region;GO:0016604//nuclear body;GO:0000783//nuclear telomere cap complex;GO:0070187//shelterin complex","GO:0042162//telomeric DNA binding;GO:0070182//DNA polymerase binding;GO:0044877//macromolecular complex binding","GO:0032202//telomere assembly;GO:0070200//establishment of protein localization to telomere;GO:0070198//protein localization to chromosome, telomeric region;GO:0001655//urogenital system development;GO:0051973//positive regulation of telomerase activity;GO:0035282//segmentation;GO:0031848//protection from non-homologous end joining at telomere;GO:0030326//embryonic limb morphogenesis;GO:0016233//telomere capping;GO:0006886//intracellular protein transport;GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0060381//positive regulation of single-stranded telomeric DNA binding;GO:0001501//skeletal system development;GO:0032211//negative regulation of telomere maintenance via telomerase;GO:0000723//telomere maintenance","K11114//adrenocortical dysplasia protein","NP_075065.2//adrenocortical dysplasia protein homolog isoform 2 [Homo sapiens];NP_001075955.1//adrenocortical dysplasia protein homolog isoform 1 [Homo sapiens];NP_001075956.1//adrenocortical dysplasia protein homolog isoform 3 [Homo sapiens]","1//3;2//1"]
[1760,2723,33.48,40.96,0.290916187449656,{"v":5.94092967457401e-06,"d":"5.94E-06"},"*",{"v":1.113134e-06,"d":"1.11E-06"},"DMPK","GO:0031965//nuclear membrane;GO:0031307//integral component of mitochondrial outer membrane;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0033017//sarcoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005640//nuclear outer membrane","GO:0046872//metal ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0017020//myosin phosphatase regulator activity;GO:0031072//heat shock protein binding","GO:1903779//regulation of cardiac conduction;GO:0014722//regulation of skeletal muscle contraction by calcium ion signaling;GO:0002028//regulation of sodium ion transport;GO:0006468//protein phosphorylation;GO:0051823//regulation of synapse structural plasticity;GO:0014853//regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction;GO:0010830//regulation of myotube differentiation;GO:0010657//muscle cell apoptotic process;GO:0018105//peptidyl-serine phosphorylation;GO:0008016//regulation of heart contraction;GO:0006874//cellular calcium ion homeostasis;GO:0006998//nuclear envelope organization","K08788//dystrophia myotonica-protein kinase [EC:2.7.11.1]","NP_001075029.1//myotonin-protein kinase isoform 3 [Homo sapiens];NP_001075031.1//myotonin-protein kinase isoform 4 [Homo sapiens];NP_004400.4//myotonin-protein kinase isoform 2 [Homo sapiens];NP_001275693.1//myotonin-protein kinase isoform 5 [Homo sapiens];NP_001075032.1//myotonin-protein kinase isoform 1 [Homo sapiens];AAC14450.1//myotonic dystrophy kinase [Homo sapiens];XP_014198194.1//PREDICTED: myotonin-protein kinase isoform X1 [Pan paniscus]","1//3;4;2//1"]
[51083,830,8.12,9.93,0.290313990343198,0.301274998226685,"*",0.1765516,"GAL","GO:0030141//secretory granule;GO:0005615//extracellular space;GO:0005794//Golgi apparatus;GO:0005622//intracellular;GO:0005576//extracellular region;GO:0043025//neuronal cell body","GO:0031765//type 2 galanin receptor binding;GO:0031764//type 1 galanin receptor binding;GO:0031763//galanin receptor binding;GO:0031766//type 3 galanin receptor binding;GO:0005184//neuropeptide hormone activity;GO:0004966//galanin receptor activity","GO:0007399//nervous system development;GO:0050672//negative regulation of lymphocyte proliferation;GO:0043627//response to estrogen;GO:0051464//positive regulation of cortisol secretion;GO:0030073//insulin secretion;GO:0043065//positive regulation of apoptotic process;GO:0007218//neuropeptide signaling pathway;GO:1902608//positive regulation of large conductance calcium-activated potassium channel activity;GO:0042493//response to drug;GO:0010737//protein kinase A signaling;GO:0032868//response to insulin;GO:0031943//regulation of glucocorticoid metabolic process;GO:0035902//response to immobilization stress;GO:0019933//cAMP-mediated signaling;GO:0006954//inflammatory response;GO:1902891//negative regulation of root hair elongation;GO:0007631//feeding behavior;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0051795//positive regulation of timing of catagen","K05244//galanin","EAW74716.1//galanin, isoform CRA_b, partial [Homo sapiens]",4]
[4736,719,467.46,571.61,0.29018823523302,{"v":2.50718788058124e-20,"d":"2.51E-20"},"*",{"v":1.188144e-21,"d":"1.19E-21"},"RPL10A","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0015934//large ribosomal subunit;GO:0005925//focal adhesion;GO:0022625//cytosolic large ribosomal subunit;GO:0005829//cytosol;GO:0005739//mitochondrion","GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome","GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006364//rRNA processing;GO:0045471//response to ethanol;GO:0000470//maturation of LSU-rRNA;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006413//translational initiation;GO:0006412//translation;GO:0019083//viral transcription","K02865//large subunit ribosomal protein L10Ae","XP_002749582.2//PREDICTED: 60S ribosomal protein L10a-like [Callithrix jacchus]",4]
[8809,3661,0.09,0.11,0.289506617194985,0.830555166459112,"*",0.751524,"IL18R1","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004872//receptor activity;GO:0042008//interleukin-18 receptor activity;GO:0004908//interleukin-1 receptor activity","GO:0045063//T-helper 1 cell differentiation;GO:0030101//natural killer cell activation;GO:0007165//signal transduction;GO:0006955//immune response;GO:0042346//positive regulation of NF-kappaB import into nucleus;GO:0032729//positive regulation of interferon-gamma production","K05173//interleukin 18 receptor 1","NP_003846.1//interleukin-18 receptor 1 isoform 1 precursor [Homo sapiens];XP_005264096.1//PREDICTED: interleukin-18 receptor 1 isoform X1 [Homo sapiens]","1//3;3//A2MP1"]
[55505,552,496.07,606.19,0.289226340530441,{"v":2.93188841931034e-16,"d":"2.93E-16"},"*",{"v":1.862944e-17,"d":"1.86E-17"},"NOP10","GO:0005654//nucleoplasm;GO:0072589//box H/ACA scaRNP complex;GO:0005732//small nucleolar ribonucleoprotein complex;GO:0090661//box H/ACA telomerase RNP complex;GO:0031429//box H/ACA snoRNP complex;GO:0016604//nuclear body;GO:0030529//intracellular ribonucleoprotein complex;GO:0005697//telomerase holoenzyme complex;GO:0019013//viral nucleocapsid","GO:0030515//snoRNA binding;GO:0003723//RNA binding;GO:0034513//box H/ACA snoRNA binding;GO:0070034//telomerase RNA binding","GO:0031120//snRNA pseudouridine synthesis;GO:1904874//positive regulation of telomerase RNA localization to Cajal body;GO:0042254//ribosome biogenesis;GO:0007004//telomere maintenance via telomerase;GO:0031118//rRNA pseudouridine synthesis;GO:0001522//pseudouridine synthesis;GO:0000454//snoRNA guided rRNA pseudouridine synthesis","K11130//H/ACA ribonucleoprotein complex subunit 3","NP_061118.1//H/ACA ribonucleoprotein complex subunit 3 [Homo sapiens]","3//A2MP1"]
[51374,1035,144.69,176.71,0.28841846822413,{"v":2.31406236973995e-08,"d":"2.31E-08"},"*",{"v":3.06388E-9,"d":"3.06E-09"},"ATRAID","GO:0005765//lysosomal membrane;GO:0005635//nuclear envelope;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0048471//perinuclear region of cytoplasm","NA","GO:0033689//negative regulation of osteoblast proliferation;GO:0010468//regulation of gene expression;GO:0030501//positive regulation of bone mineralization;GO:0030154//cell differentiation;GO:1903363//negative regulation of cellular protein catabolic process;GO:0045669//positive regulation of osteoblast differentiation","K14386//solute carrier family 5 (sodium-dependent multivitamin transporter), member 6","NP_542159.3//all-trans retinoic acid-induced differentiation factor isoform b [Homo sapiens]","1//3;4;3//A2MP1"]
[80148,2480,10.36,12.65,0.288113381895119,0.0227781639573421,"*",0.00869118,"PQLC1","GO:0016021//integral component of membrane","NA","NA","K11448//lysine-specific demethylase 6B [EC:1.14.11.-]","NP_001139817.1//PQ-loop repeat-containing protein 1 isoform 3 [Homo sapiens];XP_022369390.1//PQ-loop repeat-containing protein 1 isoform X3 [Enhydra lutris kenyoni];NP_079354.2//PQ-loop repeat-containing protein 1 isoform 1 [Homo sapiens]","1//3;4"]
[9245,2240,57.98,70.73,0.286766927903848,{"v":1.42342946124819e-08,"d":"1.42E-08"},"*",{"v":1.841886e-09,"d":"1.84E-09"},"GCNT3","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0047225//acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity;GO:0008109//N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity;GO:0003829//beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity","GO:0048729//tissue morphogenesis;GO:0006493//protein O-linked glycosylation;GO:0002426//immunoglobulin production in mucosal tissue;GO:0060993//kidney morphogenesis;GO:0005975//carbohydrate metabolic process;GO:0050892//intestinal absorption;GO:0016266//O-glycan processing","K09662//N-acetylglucosaminyltransferase 3, mucin type [EC:2.4.1.-]","NP_004742.1//beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 [Homo sapiens]","2//1"]
[3108,1122,4.01,4.89,0.286232228497313,0.418523374892601,"*",0.274448,"HLA-DMA","GO:0070062//extracellular exosome;GO:0043231//intracellular membrane-bounded organelle;GO:0009986//cell surface;GO:0042613//MHC class II protein complex;GO:0016021//integral component of membrane","GO:0023026//MHC class II protein complex binding","GO:0002503//peptide antigen assembly with MHC class II protein complex;GO:0006955//immune response;GO:0002504//antigen processing and presentation of peptide or polysaccharide antigen via MHC class II","K06752//major histocompatibility complex, class II","NP_006111.2//HLA class II histocompatibility antigen, DM alpha chain precursor [Homo sapiens]","3//A2MP1"]
[9409,1929,7.96,9.7,0.285216316530841,0.0863924435508138,"*",0.0395402,"PEX16","GO:0016020//membrane;GO:0005779//integral component of peroxisomal membrane;GO:0005783//endoplasmic reticulum;GO:0005777//peroxisome;GO:0005789//endoplasmic reticulum membrane;GO:0005778//peroxisomal membrane","GO:0008022//protein C-terminus binding","GO:0007031//peroxisome organization;GO:0016557//peroxisome membrane biogenesis;GO:0032581//ER-dependent peroxisome organization;GO:0070972//protein localization to endoplasmic reticulum;GO:0022615//protein to membrane docking;GO:0016558//protein import into peroxisome matrix;GO:0045046//protein import into peroxisome membrane;GO:0006625//protein targeting to peroxisome","K13335//peroxin-16","XP_010369352.1//PREDICTED: peroxisomal biogenesis factor 16 isoform X3 [Rhinopithecus roxellana];XP_019512030.1//PREDICTED: peroxisomal biogenesis factor 16 [Hipposideros armiger]","2//1"]
[2010,1370,92.9,113.16,0.284613580126237,{"v":3.37399428650392e-08,"d":"3.37E-08"},"*",{"v":4.58554e-09,"d":"4.59E-09"},"EMD","GO:0016020//membrane;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0005783//endoplasmic reticulum;GO:0005874//microtubule;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0032541//cortical endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005637//nuclear inner membrane;GO:0031616//spindle pole centrosome;GO:0005640//nuclear outer membrane","GO:0003779//actin binding;GO:0048487//beta-tubulin binding;GO:0045296//cadherin binding","GO:0046827//positive regulation of protein export from nucleus;GO:0007077//mitotic nuclear envelope disassembly;GO:0006936//muscle contraction;GO:0007517//muscle organ development;GO:0048147//negative regulation of fibroblast proliferation;GO:0007084//mitotic nuclear envelope reassembly;GO:0035914//skeletal muscle cell differentiation;GO:0060828//regulation of canonical Wnt signaling pathway;GO:0035414//negative regulation of catenin import into nucleus;GO:0071363//cellular response to growth factor stimulus","K12569//emerin","NP_000108.1//emerin [Homo sapiens]","2//1"]
[51116,1516,99.03,120.58,0.284053090094075,{"v":1.69158166504065e-09,"d":"1.69E-09"},"*",{"v":1.95378e-10,"d":"1.95E-10"},"MRPS2","GO:0005763//mitochondrial small ribosomal subunit;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0015935//small ribosomal subunit","GO:0003735//structural constituent of ribosome","GO:0032543//mitochondrial translation;GO:0006412//translation;GO:0070126//mitochondrial translational termination;GO:0070125//mitochondrial translational elongation","K02967//small subunit ribosomal protein S2","XP_006717199.1//PREDICTED: 28S ribosomal protein S2, mitochondrial isoform X1 [Homo sapiens]",4]
[598,2520,145.92,177.6,0.283453947072727,{"v":5.71877476683938e-20,"d":"5.72E-20"},"*",{"v":2.7638E-21,"d":"2.76E-21"},"BCL2L1","GO:0005759//mitochondrial matrix;GO:0097136//Bcl-2 family protein complex;GO:0031965//nuclear membrane;GO:0005783//endoplasmic reticulum;GO:0005813//centrosome;GO:0030054//cell junction;GO:0005741//mitochondrial outer membrane;GO:0005737//cytoplasm;GO:0030672//synaptic vesicle membrane;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0042802//identical protein binding;GO:0051434//BH3 domain binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0019901//protein kinase binding","GO:0090201//negative regulation of release of cytochrome c from mitochondria;GO:0008584//male gonad development;GO:0043065//positive regulation of apoptotic process;GO:0046898//response to cycloheximide;GO:0070584//mitochondrion morphogenesis;GO:1903077//negative regulation of protein localization to plasma membrane;GO:0046902//regulation of mitochondrial membrane permeability;GO:0043524//negative regulation of neuron apoptotic process;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway;GO:0000910//cytokinesis;GO:0043066//negative regulation of apoptotic process;GO:0001541//ovarian follicle development;GO:0006915//apoptotic process;GO:0007093//mitotic cell cycle checkpoint;GO:0007281//germ cell development;GO:0071839//apoptotic process in bone marrow;GO:0097284//hepatocyte apoptotic process;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0051402//neuron apoptotic process;GO:0019050//suppression by virus of host apoptotic process;GO:0034097//response to cytokine;GO:0008637//apoptotic mitochondrial changes;GO:0007283//spermatogenesis;GO:1902230//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage;GO:0008283//cell proliferation;GO:0006897//endocytosis;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0001836//release of cytochrome c from mitochondria;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0060154//cellular process regulating host cell cycle in response to virus;GO:0009566//fertilization;GO:1900118//negative regulation of execution phase of apoptosis;GO:0001701//in utero embryonic development;GO:0071480//cellular response to gamma radiation;GO:0071230//cellular response to amino acid stimulus;GO:2000811//negative regulation of anoikis;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway;GO:0010507//negative regulation of autophagy;GO:0040007//growth;GO:0042981//regulation of apoptotic process;GO:0051881//regulation of mitochondrial membrane potential;GO:0071312//cellular response to alkaloid;GO:0008284//positive regulation of cell proliferation","K04570//Bcl-2-like 1 (apoptosis regulator Bcl-X)","EDL05992.1//Bcl2-like 1, isoform CRA_c, partial [Mus musculus];NP_001182.1//bcl-2-like protein 1 isoform Bcl-X(S) [Homo sapiens]","1//3;3//A2MP1;2//1"]
[4155,4605,8.82,10.73,0.282799515199001,0.00143639789103538,"*",0.000414266,"MBP","GO:0033269//internode region of axon;GO:0005634//nucleus;GO:0043218//compact myelin;GO:0043234//protein complex;GO:0043209//myelin sheath;GO:0005622//intracellular;GO:0071944//cell periphery;GO:0005886//plasma membrane;GO:0043025//neuronal cell body","GO:0002020//protease binding;GO:0005516//calmodulin binding;GO:0019911//structural constituent of myelin sheath","GO:1904209//positive regulation of chemokine (C-C motif) ligand 2 secretion;GO:0042552//myelination;GO:0021762//substantia nigra development;GO:0000165//MAPK cascade;GO:0035633//maintenance of permeability of blood-brain barrier;GO:0007417//central nervous system development;GO:0009636//response to toxic substance;GO:0061024//membrane organization;GO:0008366//axon ensheathment;GO:0034115//negative regulation of heterotypic cell-cell adhesion;GO:0007605//sensory perception of sound;GO:1904685//positive regulation of metalloendopeptidase activity;GO:0007268//chemical synaptic transmission;GO:0006955//immune response;GO:2000778//positive regulation of interleukin-6 secretion","K17269//myelin basic protein","BAD92223.1//Myelin basic protein variant, partial [Homo sapiens];NP_001020272.1//Golli-MBP isoform 1 [Homo sapiens];EAW66598.1//myelin basic protein, isoform CRA_g [Homo sapiens];EAW66595.1//myelin basic protein, isoform CRA_d [Homo sapiens];EAW66596.1//myelin basic protein, isoform CRA_e [Homo sapiens]","1//3;2//1"]
[51754,3388,3.1,3.77,0.282296307994427,0.505589549328768,"*",0.351292,"TMEM8B","GO:0016021//integral component of membrane","NA","NA","K04953//cyclic nucleotide gated channel beta 3;K11661//helicase SRCAP [EC:3.6.4.-]","XP_011746507.1//PREDICTED: transmembrane protein 8B isoform X2 [Macaca nemestrina];AAF34820.1//NAG-5 protein [Homo sapiens];XP_017713268.1//PREDICTED: transmembrane protein 8B isoform X2 [Rhinopithecus bieti]","3//A2MP1;2//1"]
[122769,1503,21.47,26.1,0.281727615598474,0.071562350731982,"*",0.0318254,"LRR1","GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005737//cytoplasm","NA","GO:0043687//post-translational protein modification;GO:0007165//signal transduction;GO:0016567//protein ubiquitination","K10348//LRR-repeat protein 1","NP_982292.1//leucine-rich repeat protein 1 isoform 3 [Homo sapiens];CAD62625.1//unnamed protein product, partial [Homo sapiens]","1//3;3//A2MP1"]
[746,420,143.34,174.12,0.280640665610412,0.000537616568595041,"*",0.000142532,"TMEM258","NA","NA","NA","NA","XP_021007951.1//transmembrane protein 258 [Mus caroli]","3//A2MP1"]
[10318,2814,52.36,63.55,0.27942702794708,{"v":1.2290820952381E-8,"d":"1.23E-08"},"*",{"v":1.58348E-9,"d":"1.58E-09"},"TNIP1","GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005737//cytoplasm","GO:0031593//polyubiquitin modification-dependent protein binding;GO:0051019//mitogen-activated protein kinase binding;GO:0042802//identical protein binding","GO:0007159//leukocyte cell-cell adhesion;GO:0009101//glycoprotein biosynthetic process;GO:1903003//positive regulation of protein deubiquitination;GO:0071222//cellular response to lipopolysaccharide;GO:0050729//positive regulation of inflammatory response;GO:0085032//modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade;GO:0045071//negative regulation of viral genome replication;GO:0016579//protein deubiquitination;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0006954//inflammatory response;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0050727//regulation of inflammatory response;GO:0006952//defense response;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006412//translation;GO:0002755//MyD88-dependent toll-like receptor signaling pathway","K10352//myosin heavy chain;K14000//ribosome-binding protein 1;K12478//early endosome antigen 1;K20478//golgin subfamily B member 1","NP_001245385.1//TNFAIP3-interacting protein 1 isoform 6 [Homo sapiens];BAH12846.1//unnamed protein product [Homo sapiens];NP_001239321.1//TNFAIP3-interacting protein 1 isoform 4 [Homo sapiens];NP_006049.3//TNFAIP3-interacting protein 1 isoform 3 [Homo sapiens];NP_001239314.1//TNFAIP3-interacting protein 1 isoform 1 [Homo sapiens];NP_001245384.1//TNFAIP3-interacting protein 1 isoform 5 [Homo sapiens]","4;1//3"]
[3487,2246,1554.22,1885.84,0.279016547046187,{"v":5.27681243515151e-199,"d":"5.28E-199"},"*",{"v":1.090114E-201,"d":"1.09E-201"},"IGFBP4","GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0005576//extracellular region","GO:0005520//insulin-like growth factor binding;GO:0031994//insulin-like growth factor I binding;GO:0005102//receptor binding;GO:0031995//insulin-like growth factor II binding","GO:0001558//regulation of cell growth;GO:0043687//post-translational protein modification;GO:0007165//signal transduction;GO:0043567//regulation of insulin-like growth factor receptor signaling pathway;GO:0006259//DNA metabolic process;GO:0043568//positive regulation of insulin-like growth factor receptor signaling pathway;GO:0006954//inflammatory response;GO:0044267//cellular protein metabolic process;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0008283//cell proliferation;GO:0044342//type B pancreatic cell proliferation;GO:0010906//regulation of glucose metabolic process;GO:0043410//positive regulation of MAPK cascade;GO:0001501//skeletal system development","K10138//insulin-like growth factor-binding protein 3","NP_001543.2//insulin-like growth factor-binding protein 4 precursor [Homo sapiens]","2//1"]
[113000,1895,49.03,59.47,0.278497314090518,{"v":1.36673523773346E-5,"d":"1.37E-05"},"*",{"v":2.70284E-6,"d":"2.70E-06"},"RPUSD1","NA","GO:0003723//RNA binding;GO:0009982//pseudouridine synthase activity","GO:0031119//tRNA pseudouridine synthesis;GO:0000455//enzyme-directed rRNA pseudouridine synthesis;GO:0001522//pseudouridine synthesis","K01855//tRNA pseudouridine38/39 synthase [EC:5.4.99.45]","AAH12951.2//RPUSD1 protein, partial [Homo sapiens];NP_001311015.1//RNA pseudouridylate synthase domain-containing protein 1 isoform 2 [Homo sapiens];NP_478072.1//RNA pseudouridylate synthase domain-containing protein 1 isoform 1 [Homo sapiens]","1//3;2//1"]
[353514,1327,1.74,2.11,0.278155692858457,0.602528402473109,"*",0.445352,"LILRA5","GO:0070062//extracellular exosome;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","NA","GO:0045087//innate immune response","K06512//leukocyte immunoglobulin-like receptor","NP_871715.1//leukocyte immunoglobulin-like receptor subfamily A member 5 isoform 4 [Homo sapiens];NP_870994.1//leukocyte immunoglobulin-like receptor subfamily A member 5 isoform 3 [Homo sapiens];NP_067073.1//leukocyte immunoglobulin-like receptor subfamily A member 5 isoform 1 precursor [Homo sapiens];NP_871714.1//leukocyte immunoglobulin-like receptor subfamily A member 5 isoform 2 [Homo sapiens]","3//A2MP1;2//1"]
[4943,3918,7.8,9.45,0.276840205358824,0.0167746633458518,"*",6.15162E-3,"TBC1D25","GO:0012505//endomembrane system;GO:0031410//cytoplasmic vesicle;GO:0005776//autophagosome","GO:0008483//transaminase activity;GO:0017137//Rab GTPase binding;GO:0005096//GTPase activator activity","GO:0006886//intracellular protein transport;GO:0090630//activation of GTPase activity;GO:0031338//regulation of vesicle fusion;GO:0006914//autophagy;GO:1901096//regulation of autophagosome maturation;GO:0061024//membrane organization","K20168//TBC1 domain family member 15","NP_001335192.1//TBC1 domain family member 25 isoform b [Homo sapiens];NP_002527.1//TBC1 domain family member 25 isoform c [Homo sapiens];NP_001335191.1//TBC1 domain family member 25 isoform a [Homo sapiens];NP_001335194.1//TBC1 domain family member 25 isoform d [Homo sapiens]","1//3;3//A2MP1"]
[84182,2750,2.75,3.33,0.27609055865924,0.283632352867345,"*",0.1640998,"MINDY4","NA","GO:0036459//thiol-dependent ubiquitinyl hydrolase activity","NA","K08742//E3 ubiquitin-protein ligase SIAH2 [EC:2.3.2.27];K20465//oxysterol-binding protein-related protein 9/10/11","NP_115598.2//probable ubiquitin carboxyl-terminal hydrolase MINDY-4 [Homo sapiens]","2//1"]
[55283,2746,1.71,2.07,0.275634442613427,0.355418633165829,"*",0.216958,"MCOLN3","GO:0005765//lysosomal membrane;GO:0031901//early endosome membrane;GO:0031902//late endosome membrane;GO:0016021//integral component of membrane;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0000421//autophagosome membrane","GO:0005262//calcium channel activity","GO:0070588//calcium ion transmembrane transport;GO:0007626//locomotory behavior;GO:0042491//inner ear auditory receptor cell differentiation","K04994//mucolipin 3","XP_011540041.2//PREDICTED: mucolipin-3 isoform X1 [Homo sapiens];XP_011540042.1//PREDICTED: mucolipin-3 isoform X3 [Homo sapiens]","1//3;10//2"]
[9973,1068,15.37,18.6,0.275185456304623,0.0943022780870035,"*",0.0436976,"CCS","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0004784//superoxide dismutase activity;GO:0015035//protein disulfide oxidoreductase activity;GO:0046872//metal ion binding;GO:0016532//superoxide dismutase copper chaperone activity;GO:0005507//copper ion binding;GO:0008270//zinc ion binding;GO:0045296//cadherin binding","GO:0006801//superoxide metabolic process;GO:0015680//intracellular copper ion transport;GO:0034599//cellular response to oxidative stress;GO:0051353//positive regulation of oxidoreductase activity;GO:0030001//metal ion transport","K04569//copper chaperone for superoxide dismutase","NP_005116.1//copper chaperone for superoxide dismutase [Homo sapiens]","1//3"]
[55317,1836,20.02,24.21,0.274161105162943,0.00696337839037232,"*",0.00231822,"AP5S1","NA","NA","NA","K19024//AP-5 complex subunit sigma-1","XP_011907569.1//PREDICTED: AP-5 complex subunit sigma-1 isoform X2 [Cercocebus atys]","1//3;2//1"]
[80097,954,88.87,107.46,0.274031349874134,{"v":2.52526435325924E-5,"d":"2.53E-05"},"*",{"v":5.26268e-06,"d":"5.26E-06"},"MZT2B","GO:0005654//nucleoplasm;GO:0005815//microtubule organizing center;GO:0008274//gamma-tubulin ring complex;GO:0005829//cytosol;GO:0005819//spindle;GO:0005813//centrosome","NA","NA","K16574//mitotic-spindle organizing protein 2A/2B","XP_001166562.2//PREDICTED: mitotic-spindle organizing protein 2B-like [Pan troglodytes];NP_001317213.1//mitotic-spindle organizing protein 2B isoform 3 [Homo sapiens];XP_009441596.1//PREDICTED: mitotic-spindle organizing protein 2B isoform X1 [Pan troglodytes]","4;1//3"]
[91689,1585,5.61,6.78,0.273284502527551,0.243056543839733,"*",0.1367136,"SMDT1","GO:0005759//mitochondrial matrix;GO:0005634//nucleus;GO:1990246//uniplex complex;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0031305//integral component of mitochondrial inner membrane","NA","GO:0006851//mitochondrial calcium ion transmembrane transport;GO:0051560//mitochondrial calcium ion homeostasis;GO:0036444//mitochondrial calcium uptake","NA","NP_201575.3//essential MCU regulator, mitochondrial precursor [Homo sapiens]",4]
[257144,3355,0.24,0.29,0.273018494406416,0.772196926937693,"*",0.67421,"GCSAM","GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0003779//actin binding;GO:0045159//myosin II binding;GO:0019901//protein kinase binding","GO:0050855//regulation of B cell receptor signaling pathway;GO:2000402//negative regulation of lymphocyte migration","NA","NP_001177188.1//germinal center-associated signaling and motility protein isoform 3 [Homo sapiens];NP_001177189.1//germinal center-associated signaling and motility protein isoform 4 [Homo sapiens];NP_689998.1//germinal center-associated signaling and motility protein isoform 1 [Homo sapiens]","4;1//3"]
[387707,1851,37.53,45.32,0.272103570933539,1.01236961304348E-4,"*",{"v":2.33224e-05,"d":"2.33E-05"},"CC2D2B","NA","NA","NA","K01510//apyrase [EC:3.6.1.5];K19352//coiled-coil and C2 domain-containing protein 2A","NP_001335937.1//protein CC2D2B isoform 3 [Homo sapiens];NP_001001732.2//protein CC2D2B isoform 2 [Homo sapiens];XP_011538093.1//PREDICTED: protein CC2D2B isoform X3 [Homo sapiens];NP_001123918.2//protein CC2D2B isoform 4 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[51372,580,114.9,138.62,0.270756625574845,3.41118009350394E-4,"*",{"v":8.6785e-05,"d":"8.68E-05"},"TMA7","NA","NA","NA","K06562//lysosomal-associated membrane protein 3","EDL06269.1//mCG52157, partial [Mus musculus]","1//3;5"]
[10300,2661,16.46,19.85,0.270174671608695,3.31475436476976E-3,"*",0.001031944,"KATNB1","GO:0016020//membrane;GO:0008352//katanin complex;GO:0030424//axon;GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005874//microtubule;GO:0015630//microtubule cytoskeleton;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0043025//neuronal cell body;GO:0030496//midbody;GO:0030426//growth cone;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0070840//dynein complex binding;GO:0008568//microtubule-severing ATPase activity;GO:0046982//protein heterodimerization activity;GO:0008017//microtubule binding","GO:0006605//protein targeting;GO:0031117//positive regulation of microtubule depolymerization;GO:0010976//positive regulation of neuron projection development;GO:0007079//mitotic chromosome movement towards spindle pole;GO:0051301//cell division;GO:0007026//negative regulation of microtubule depolymerization;GO:0051013//microtubule severing;GO:0007049//cell cycle;GO:0010942//positive regulation of cell death","K18643//katanin p80 WD40 repeat-containing subunit B1","NP_005877.2//katanin p80 WD40 repeat-containing subunit B1 [Homo sapiens]","2//1"]
[7627,2276,3.9,4.7,0.269186632815389,0.711700792362769,"*",0.597376,"ZNF75A","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein;K09229//KRAB and SCAN domains-containing zinc finger protein","XP_012503228.1//PREDICTED: zinc finger protein 75A isoform X2 [Propithecus coquereli];XP_012661173.1//PREDICTED: zinc finger protein 75A [Otolemur garnettii];XP_006054991.1//PREDICTED: uncharacterized protein LOC102394770 [Bubalus bubalis]","1//3;3//A2MP1"]
[6152,579,501.54,603.82,0.267753776601909,{"v":7.67492945679012e-15,"d":"7.67E-15"},"*",{"v":5.44846E-16,"d":"5.45E-16"},"RPL24","GO:0005840//ribosome;GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0022625//cytosolic large ribosomal subunit;GO:0005737//cytoplasm;GO:0022626//cytosolic ribosome","GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0045296//cadherin binding","GO:0031290//retinal ganglion cell axon guidance;GO:0060041//retina development in camera-type eye;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0000027//ribosomal large subunit assembly;GO:0006364//rRNA processing;GO:0006413//translational initiation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0007093//mitotic cell cycle checkpoint;GO:1902626//assembly of large subunit precursor of preribosome;GO:0010458//exit from mitosis;GO:0019083//viral transcription;GO:0006412//translation;GO:0021554//optic nerve development","K02896//large subunit ribosomal protein L24e","AAH02110.2//Rpl24 protein, partial [Mus musculus]","3//A2MP1"]
[56964,1980,0.54,0.65,0.267480310864986,0.796344158759253,"*",0.707158,"WDR93","NA","GO:0016651//oxidoreductase activity, acting on NAD(P)H","GO:0022900//electron transport chain","K17985//activating molecule in BECN1-regulated autophagy protein 1;K15696//RING finger protein 113B;K01064//wingless-type MMTV integration site family, member 9","NP_064597.1//WD repeat-containing protein 93 isoform 1 [Homo sapiens];NP_001271324.1//WD repeat-containing protein 93 isoform 2 [Homo sapiens];NP_001271325.1//WD repeat-containing protein 93 isoform 3 [Homo sapiens]","1//3"]
[5900,3683,8.62,10.37,0.266656119724128,0.0146092665903175,"*",5.27064E-3,"RALGDS","GO:0005634//nucleus;GO:0005903//brush border;GO:0005829//cytosol;GO:0005622//intracellular","GO:0005085//guanyl-nucleotide exchange factor activity;GO:0030695//GTPase regulator activity","GO:0007264//small GTPase mediated signal transduction;GO:0007265//Ras protein signal transduction","K08732//ral guanine nucleotide dissociation stimulator","NP_001258703.1//ral guanine nucleotide dissociation stimulator isoform 3 [Homo sapiens];NP_006257.1//ral guanine nucleotide dissociation stimulator isoform 1 [Homo sapiens];NP_001035827.1//ral guanine nucleotide dissociation stimulator isoform 2 [Homo sapiens];XP_016817454.1//PREDICTED: ral guanine nucleotide dissociation stimulator isoform X8 [Pan troglodytes];NP_001258705.1//ral guanine nucleotide dissociation stimulator isoform 5 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[10150,4755,4.6,5.53,0.265645619290332,0.084448464930412,"*",0.038365,"MBNL2","GO:0005654//nucleoplasm;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0046872//metal ion binding","GO:0043484//regulation of RNA splicing;GO:0006397//mRNA processing;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0008380//RNA splicing","K14943//muscleblind","NP_997187.1//muscleblind-like protein 2 isoform 3 [Homo sapiens];NP_659002.1//muscleblind-like protein 2 isoform 1 [Homo sapiens];NP_001292999.1//muscleblind-like protein 2 isoform 4 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[8751,2926,29.35,35.26,0.264671971322767,{"v":2.22938017259192e-05,"d":"2.23E-05"},"*",{"v":4.59302e-06,"d":"4.59E-06"},"ADAM15","GO:0070062//extracellular exosome;GO:0009986//cell surface;GO:0042995//cell projection;GO:0016021//integral component of membrane;GO:0001669//acrosomal vesicle;GO:0005886//plasma membrane;GO:0005912//adherens junction","GO:0046872//metal ion binding;GO:0008237//metallopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0005178//integrin binding;GO:0017124//SH3 domain binding","GO:1900121//negative regulation of receptor binding;GO:0030308//negative regulation of cell growth;GO:0060317//cardiac epithelial to mesenchymal transition;GO:0001525//angiogenesis;GO:0070528//protein kinase C signaling;GO:0030336//negative regulation of cell migration;GO:0042246//tissue regeneration;GO:0008584//male gonad development;GO:0007160//cell-matrix adhesion;GO:0022617//extracellular matrix disassembly;GO:0030198//extracellular matrix organization;GO:0001953//negative regulation of cell-matrix adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0045087//innate immune response;GO:0030574//collagen catabolic process","K06836//disintegrin and metalloproteinase domain-containing protein 15 [EC:3.4.24.-]","BAG59477.1//unnamed protein product [Homo sapiens];XP_007975128.1//PREDICTED: disintegrin and metalloproteinase domain-containing protein 15 isoform X12 [Chlorocebus sabaeus];XP_007975121.1//PREDICTED: disintegrin and metalloproteinase domain-containing protein 15 isoform X7 [Chlorocebus sabaeus];XP_007975117.1//PREDICTED: disintegrin and metalloproteinase domain-containing protein 15 isoform X3 [Chlorocebus sabaeus];AAS48591.1//ADAM15 isoform 3a [Homo sapiens];XP_007975130.1//PREDICTED: disintegrin and metalloproteinase domain-containing protein 15 isoform X14 [Chlorocebus sabaeus];XP_007975114.1//PREDICTED: disintegrin and metalloproteinase domain-containing protein 15 isoform X1 [Chlorocebus sabaeus];XP_007975125.1//PREDICTED: disintegrin and metalloproteinase domain-containing protein 15 isoform X10 [Chlorocebus sabaeus];NP_997078.1//disintegrin and metalloproteinase domain-containing protein 15 isoform 4 preproprotein [Homo sapiens]","4;1//3;2//1"]
[51011,1313,19.06,22.88,0.263538932868447,0.038954959017094,"*",0.01597802,"FAHD2A","NA","GO:0046872//metal ion binding;GO:0016787//hydrolase activity","GO:0008152//metabolic process","K01557//acylpyruvate hydrolase [EC:3.7.1.5]","NP_057128.2//fumarylacetoacetate hydrolase domain-containing protein 2A [Homo sapiens]","2//1"]
[1370,3025,0.15,0.18,0.263034405833794,0.695635420185143,"*",0.578622,"CPN2","GO:0070062//extracellular exosome;GO:0072562//blood microparticle;GO:0005576//extracellular region","GO:0004181//metallocarboxypeptidase activity;GO:0030234//enzyme regulator activity","GO:0030449//regulation of complement activation;GO:0050821//protein stabilization","K13023//carboxypeptidase N regulatory subunit","EAW78055.1//hCG2040284, partial [Homo sapiens]","1//3;3//A2MP1"]
[55697,3125,21.26,25.51,0.262921302071368,4.52881108903288E-4,"*",1.181392E-4,"VAC14","GO:0010008//endosome membrane;GO:0005783//endoplasmic reticulum;GO:0031901//early endosome membrane;GO:0070772//PAS complex;GO:0031902//late endosome membrane;GO:0000139//Golgi membrane","GO:0004872//receptor activity","GO:0007165//signal transduction;GO:0006661//phosphatidylinositol biosynthetic process;GO:0016032//viral process;GO:0043550//regulation of lipid kinase activity","K15305//vacuole morphology and inheritance protein 14","NP_060522.3//protein VAC14 homolog isoform 1 [Homo sapiens]","4;1//3"]
[27243,942,69.14,82.91,0.262025515977615,0.000523998655802937,"*",0.0001384952,"CHMP2A","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0000785//chromatin;GO:0005635//nuclear envelope;GO:0005622//intracellular;GO:0031902//late endosome membrane;GO:0030117//membrane coat;GO:0005829//cytosol;GO:0000815//ESCRT III complex","GO:0031210//phosphatidylcholine binding;GO:0019904//protein domain specific binding","GO:1903543//positive regulation of exosomal secretion;GO:0006997//nucleus organization;GO:1901673//regulation of mitotic spindle assembly;GO:0051260//protein homooligomerization;GO:0019058//viral life cycle;GO:0039702//viral budding via host ESCRT complex;GO:0050792//regulation of viral process;GO:0010324//membrane invagination;GO:1903723//negative regulation of centriole elongation;GO:1902188//positive regulation of viral release from host cell;GO:0000920//cell separation after cytokinesis;GO:0007080//mitotic metaphase plate congression;GO:0015031//protein transport;GO:0016197//endosomal transport;GO:0045184//establishment of protein localization;GO:0051291//protein heterooligomerization;GO:0007034//vacuolar transport;GO:0010824//regulation of centrosome duplication;GO:0051258//protein polymerization;GO:1904903//ESCRT III complex disassembly;GO:0036258//multivesicular body assembly;GO:0010458//exit from mitosis;GO:0060548//negative regulation of cell death;GO:0016236//macroautophagy;GO:0031468//nuclear envelope reassembly","K12191//charged multivesicular body protein 2A","XP_007175446.1//PREDICTED: charged multivesicular body protein 2a isoform X1 [Balaenoptera acutorostrata scammoni];XP_007955188.1//PREDICTED: charged multivesicular body protein 2a isoform X1 [Orycteropus afer afer]","3//A2MP1;2//1"]
[79767,2548,1.41,1.69,0.261328083883391,0.5187870507201,"*",0.36306,"ELMO3","NA","NA","GO:0016477//cell migration","K19241//engulfment and cell motility protein 3","EAW83097.1//engulfment and cell motility 3, isoform CRA_a [Homo sapiens]","3//A2MP1"]
[10598,1391,141.43,169.49,0.261111980360861,{"v":9.43514614532872e-09,"d":"9.44E-09"},"*",{"v":1.194898e-09,"d":"1.19E-09"},"AHSA1","GO:0070062//extracellular exosome;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol","GO:0001671//ATPase activator activity;GO:0051087//chaperone binding;GO:0045296//cadherin binding","GO:0006950//response to stress","K04131//muscarinic acetylcholine receptor M3","NP_036243.1//activator of 90 kDa heat shock protein ATPase homolog 1 isoform 1 [Homo sapiens]","1//3;2//1"]
[92822,4613,8.29,9.93,0.260421616032624,0.00931566814679569,"*",0.00319406,"ZNF276","GO:0005634//nucleus;GO:0000776//kinetochore;GO:0000777//condensed chromosome kinetochore","GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","NP_001106997.1//zinc finger protein 276 isoform a [Homo sapiens]","1//3;3//A2MP1"]
[7226,5774,3.76,4.5,0.2591923395394,0.284865294641314,"*",0.1650628,"TRPM2","GO:0005765//lysosomal membrane;GO:0042995//cell projection;GO:0101003//ficolin-1-rich granule membrane;GO:0005764//lysosome;GO:0043204//perikaryon;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane;GO:0005886//plasma membrane;GO:0070821//tertiary granule membrane;GO:0030659//cytoplasmic vesicle membrane","GO:0047631//ADP-ribose diphosphatase activity;GO:0005509//calcium ion binding;GO:0005272//sodium channel activity;GO:0099604//ligand-gated calcium channel activity;GO:0005262//calcium channel activity;GO:0005261//cation channel activity;GO:0015278//calcium-release channel activity","GO:0001659//temperature homeostasis;GO:0070588//calcium ion transmembrane transport;GO:0097553//calcium ion transmembrane import into cytosol;GO:0002407//dendritic cell chemotaxis;GO:0035584//calcium-mediated signaling using intracellular calcium source;GO:0071277//cellular response to calcium ion;GO:0071502//cellular response to temperature stimulus;GO:0098703//calcium ion import across plasma membrane;GO:0071415//cellular response to purine-containing compound;GO:0043312//neutrophil degranulation;GO:0071577//zinc II ion transmembrane transport;GO:0051489//regulation of filopodium assembly;GO:0070301//cellular response to hydrogen peroxide;GO:0006816//calcium ion transport;GO:0014074//response to purine-containing compound;GO:2000249//regulation of actin cytoskeleton reorganization;GO:0006979//response to oxidative stress;GO:0097028//dendritic cell differentiation;GO:0051209//release of sequestered calcium ion into cytosol","K04977//transient receptor potential cation channel subfamily M member 2 [EC:3.6.1.13]","NP_003298.1//transient receptor potential cation channel subfamily M member 2 isoform 1 [Homo sapiens];BAB64300.1//EREG1 [Homo sapiens];NP_001307279.1//transient receptor potential cation channel subfamily M member 2 isoform 2 [Homo sapiens];NP_001307280.1//transient receptor potential cation channel subfamily M member 2 isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[51524,1785,38.14,45.64,0.258993947975926,0.000201468183897436,"*",{"v":4.91878e-05,"d":"4.92E-05"},"TMEM138","GO:0005929//cilium;GO:0016021//integral component of membrane","NA","GO:0060271//cilium assembly","NA","XP_003419415.1//PREDICTED: transmembrane protein 138 isoform X1 [Loxodonta africana]","1//3;4"]
[4267,3377,122.74,146.8,0.258246479593065,{"v":5.96576602048998e-08,"d":"5.97E-08"},"*",{"v":8.38434E-9,"d":"8.38E-09"},"CD99","GO:0005887//integral component of plasma membrane;GO:0005925//focal adhesion;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm","NA","GO:0007155//cell adhesion;GO:0050776//regulation of immune response","K06520//CD99 antigen","NP_002405.1//CD99 antigen isoform a precursor [Homo sapiens];NP_001308299.1//CD99 antigen isoform f precursor [Homo sapiens];XP_007991428.1//PREDICTED: collagen alpha-1(I) chain-like [Chlorocebus sabaeus];NP_001116370.1//CD99 antigen isoform b precursor [Homo sapiens];NP_001308298.1//CD99 antigen isoform e precursor [Homo sapiens];NP_001308297.1//CD99 antigen isoform d precursor [Homo sapiens]","4;1//3;2//1"]
[5708,2823,80.42,96.15,0.257732521426899,{"v":4.16959551817238e-09,"d":"4.17E-09"},"*",{"v":5.02732E-10,"d":"5.03E-10"},"PSMD2","GO:0034774//secretory granule lumen;GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000502//proteasome complex;GO:0022624//proteasome accessory complex;GO:0005838//proteasome regulatory particle;GO:0034515//proteasome storage granule;GO:0005829//cytosol;GO:0005576//extracellular region;GO:1904813//ficolin-1-rich granule lumen;GO:0008540//proteasome regulatory particle, base subcomplex","GO:0030234//enzyme regulator activity","GO:0043687//post-translational protein modification;GO:0038061//NIK/NF-kappaB signaling;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0006521//regulation of cellular amino acid metabolic process;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0016579//protein deubiquitination;GO:0043312//neutrophil degranulation;GO:0043488//regulation of mRNA stability;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0000209//protein polyubiquitination;GO:0055085//transmembrane transport;GO:0000165//MAPK cascade;GO:0050852//T cell receptor signaling pathway;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0042176//regulation of protein catabolic process;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:1902036//regulation of hematopoietic stem cell differentiation","K03028//26S proteasome regulatory subunit N1","XP_015355414.1//PREDICTED: 26S proteasome non-ATPase regulatory subunit 2 [Marmota marmota marmota];NP_001265638.1//26S proteasome non-ATPase regulatory subunit 2 isoform 3 [Homo sapiens];XP_017393834.1//PREDICTED: 26S proteasome non-ATPase regulatory subunit 2 [Cebus capucinus imitator]","1//3;4"]
[4708,509,101.13,120.86,0.257125813994305,0.00370002152092467,"*",0.001162308,"NDUFB2","GO:0005747//mitochondrial respiratory chain complex I;GO:0005743//mitochondrial inner membrane","GO:0008137//NADH dehydrogenase (ubiquinone) activity","GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0055114//oxidation-reduction process","K03958//NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2","NP_004537.1//NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial precursor [Homo sapiens]","2//1"]
[130752,2527,0.72,0.86,0.256339753259786,0.688429737398129,"*",0.57112,"MDH1B","GO:0005737//cytoplasm","GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0016615//malate dehydrogenase activity;GO:0030060//L-malate dehydrogenase activity","GO:0006099//tricarboxylic acid cycle;GO:0006107//oxaloacetate metabolic process;GO:0005975//carbohydrate metabolic process;GO:0006734//NADH metabolic process;GO:0006108//malate metabolic process","K00025//malate dehydrogenase [EC:1.1.1.37]","NP_001269869.1//putative malate dehydrogenase 1B isoform b [Homo sapiens];NP_001034934.1//putative malate dehydrogenase 1B isoform a [Homo sapiens];NP_001317155.1//putative malate dehydrogenase 1B isoform f [Homo sapiens]","1//3;2//1"]
[11018,1739,14.09,16.82,0.255506093945508,0.0495556023700193,"*",0.0209434,"TMED1","GO:0043231//intracellular membrane-bounded organelle;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane","GO:0005102//receptor binding","GO:0006810//transport;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0015031//protein transport","K20348//p24 family protein gamma-1","NP_006849.1//transmembrane emp24 domain-containing protein 1 precursor [Homo sapiens]","3//A2MP1"]
[535,4188,24.21,28.9,0.255466413389104,{"v":1.1364724769821E-5,"d":"1.14E-05"},"*",{"v":2.22542E-6,"d":"2.23E-06"},"ATP6V0A1","GO:0005765//lysosomal membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0010008//endosome membrane;GO:0000220//vacuolar proton-transporting V-type ATPase, V0 domain;GO:0030667//secretory granule membrane;GO:0101003//ficolin-1-rich granule membrane;GO:0016607//nuclear speck;GO:0030670//phagocytic vesicle membrane;GO:0042470//melanosome;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0016471//vacuolar proton-transporting V-type ATPase complex;GO:0005886//plasma membrane","GO:0015078//hydrogen ion transmembrane transporter activity;GO:0051117//ATPase binding;GO:0046961//proton-transporting ATPase activity, rotational mechanism","GO:0016241//regulation of macroautophagy;GO:0008286//insulin receptor signaling pathway;GO:0034220//ion transmembrane transport;GO:0070072//vacuolar proton-transporting V-type ATPase complex assembly;GO:0090383//phagosome acidification;GO:0007035//vacuolar acidification;GO:0015986//ATP synthesis coupled proton transport;GO:0015991//ATP hydrolysis coupled proton transport;GO:1901998//toxin transport;GO:0033572//transferrin transport;GO:0043312//neutrophil degranulation","K02154//V-type H+-transporting ATPase subunit a","NP_001123492.1//V-type proton ATPase 116 kDa subunit a isoform 1 isoform a [Homo sapiens];NP_001123493.1//V-type proton ATPase 116 kDa subunit a isoform 1 isoform b [Homo sapiens];NP_005168.2//V-type proton ATPase 116 kDa subunit a isoform 1 isoform c [Homo sapiens]","1//3;3//A2MP1"]
[153830,3569,27.02,32.24,0.254824069202283,{"v":1.24906931087095e-05,"d":"1.25E-05"},"*",{"v":2.45998E-6,"d":"2.46E-06"},"RNF145","GO:0016021//integral component of membrane","GO:0061630//ubiquitin protein ligase activity;GO:0008270//zinc ion binding","GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0000209//protein polyubiquitination","K15703//E3 ubiquitin-protein ligase RNF139 [EC:2.3.2.27]","NP_001186311.1//RING finger protein 145 isoform 4 [Homo sapiens];NP_001186310.1//RING finger protein 145 isoform 3 [Homo sapiens];XP_021527876.1//LOW QUALITY PROTEIN: RING finger protein 145 [Aotus nancymaae];NP_653327.1//RING finger protein 145 isoform 2 [Homo sapiens]","1//3;2//1"]
[55957,1179,16.15,19.26,0.254073538262172,0.0953391044228695,"*",0.0442616,"LIN37","NA","NA","NA","K21774//protein lin-37","XP_004060585.1//PREDICTED: protein lin-37 homolog [Gorilla gorilla gorilla]","2//1"]
[55016,5389,0.26,0.31,0.253756592245783,0.733999604133314,"*",0.63144,"2019-03-01","GO:0005765//lysosomal membrane;GO:0031902//late endosome membrane;GO:0005764//lysosome;GO:0005768//endosome;GO:0032588//trans-Golgi network membrane;GO:0031901//early endosome membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0030659//cytoplasmic vesicle membrane","GO:0042287//MHC protein binding;GO:0061630//ubiquitin protein ligase activity;GO:0008270//zinc ion binding;GO:0004842//ubiquitin-protein transferase activity","GO:0006955//immune response;GO:0002495//antigen processing and presentation of peptide antigen via MHC class II;GO:0000209//protein polyubiquitination","K10656//E3 ubiquitin-protein ligase MARCH1/8 [EC:2.3.2.27]","XP_019296632.1//PREDICTED: E3 ubiquitin-protein ligase MARCH1 isoform X8 [Panthera pardus];XP_019296631.1//PREDICTED: E3 ubiquitin-protein ligase MARCH1 isoform X7 [Panthera pardus]","1//3;3//A2MP1"]
[4189,2538,2.77,3.3,0.252580048196627,0.355611510664479,"*",0.217098,"DNAJB9","GO:0070062//extracellular exosome;GO:0005788//endoplasmic reticulum lumen;GO:0005783//endoplasmic reticulum;GO:0005730//nucleolus;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005737//cytoplasm","GO:0051787//misfolded protein binding","GO:0036498//IRE1-mediated unfolded protein response;GO:0030433//ubiquitin-dependent ERAD pathway","K09515//DnaJ homolog subfamily B member 9","NP_036460.1//dnaJ homolog subfamily B member 9 precursor [Homo sapiens]","2//1"]
[51667,3149,15.97,19.02,0.252152933449331,0.00324367375201288,"*",1.0088E-3,"NUB1","GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005829//cytosol","NA","GO:0043687//post-translational protein modification;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0034612//response to tumor necrosis factor;GO:0034341//response to interferon-gamma;GO:0016567//protein ubiquitination;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process","NA","NP_057202.3//NEDD8 ultimate buster 1 isoform 2 [Homo sapiens];NP_001230280.1//NEDD8 ultimate buster 1 isoform 1 [Homo sapiens]","1//3;4"]
[7366,2264,0.21,0.25,0.251538766995964,0.858348326079542,"*",0.787688,"UGT2B15","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0015020//glucuronosyltransferase activity","GO:0008202//steroid metabolic process;GO:0008152//metabolic process;GO:0052695//cellular glucuronidation","K00699//glucuronosyltransferase [EC:2.4.1.17]","XP_003268480.1//PREDICTED: UDP-glucuronosyltransferase 2B15 isoform X1 [Nomascus leucogenys]","3//A2MP1"]
[123228,1569,1.21,1.44,0.251061764167718,0.695436021079575,"*",0.578282,"SENP8","GO:0005634//nucleus;GO:0005829//cytosol","GO:0004175//endopeptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0019784//NEDD8-specific protease activity","GO:0043687//post-translational protein modification;GO:0016579//protein deubiquitination;GO:0016926//protein desumoylation","K08597//sentrin-specific protease 8 [EC:3.4.22.68]","XP_011519517.1//PREDICTED: sentrin-specific protease 8 isoform X1 [Homo sapiens]","1//3;3//A2MP1"]
[90627,5723,0.58,0.69,0.250543461650597,0.562308590180968,"*",0.406542,"STARD13","GO:0005811//lipid droplet;GO:0005829//cytosol;GO:0031966//mitochondrial membrane","GO:0008289//lipid binding;GO:0005096//GTPase activator activity","GO:0090051//negative regulation of cell migration involved in sprouting angiogenesis;GO:0007165//signal transduction;GO:0097498//endothelial tube lumen extension;GO:0043542//endothelial cell migration;GO:0051056//regulation of small GTPase mediated signal transduction","K20632//deleted in liver cancer protein","NP_821074.1//stAR-related lipid transfer protein 13 isoform 1 [Homo sapiens];XP_007958277.1//PREDICTED: stAR-related lipid transfer protein 13 isoform X1 [Chlorocebus sabaeus];NP_821075.1//stAR-related lipid transfer protein 13 isoform 2 [Homo sapiens];XP_014202906.1//PREDICTED: stAR-related lipid transfer protein 13 isoform X4 [Pan paniscus];NP_001230395.1//stAR-related lipid transfer protein 13 isoform 5 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[10445,1815,43.94,52.24,0.249620027123154,0.000322825431152802,"*",{"v":8.18684e-05,"d":"8.19E-05"},"MCRS1","GO:0030425//dendrite;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005783//endoplasmic reticulum;GO:0031011//Ino80 complex;GO:0005737//cytoplasm;GO:0043204//perikaryon;GO:0071339//MLL1 complex;GO:0005730//nucleolus;GO:0000123//histone acetyltransferase complex;GO:0005844//polysome","GO:0046972//histone acetyltransferase activity (H4-K16 specific);GO:0002151//G-quadruplex RNA binding;GO:0008266//poly(U) RNA binding;GO:0043995//histone acetyltransferase activity (H4-K5 specific);GO:0034046//poly(G) binding;GO:0043996//histone acetyltransferase activity (H4-K8 specific);GO:0010521//telomerase inhibitor activity","GO:0043984//histone H4-K16 acetylation;GO:1904357//negative regulation of telomere maintenance via telomere lengthening;GO:0006281//DNA repair;GO:0006355//regulation of transcription, DNA-templated;GO:0043981//histone H4-K5 acetylation;GO:0006351//transcription, DNA-templated;GO:1904751//positive regulation of protein localization to nucleolus;GO:0051974//negative regulation of telomerase activity;GO:0006464//cellular protein modification process;GO:0043982//histone H4-K8 acetylation;GO:0016579//protein deubiquitination;GO:0006310//DNA recombination","K11674//microspherule protein 1","AAC68599.1//cell cycle-regulated factor p78 [Homo sapiens];ERE81194.1//Forkhead-associated (FHA) domain containing protein [Cricetulus griseus];NP_001012300.1//microspherule protein 1 isoform 2 [Homo sapiens]","4;1//3"]
[10227,1787,56.76,67.46,0.249157728957575,{"v":2.1606962435312e-05,"d":"2.16E-05"},"*",{"v":4.4434e-06,"d":"4.44E-06"},"MFSD10","GO:0031526//brush border membrane;GO:0016021//integral component of membrane;GO:0030659//cytoplasmic vesicle membrane","GO:0008493//tetracycline transmembrane transporter activity;GO:0008514//organic anion transmembrane transporter activity","GO:0006810//transport;GO:0043252//sodium-independent organic anion transport;GO:0006915//apoptotic process","K05202//glutamate receptor, ionotropic kainate 2;K19721//collagen, type V/XI/XXIV/XXVII, alpha;K13506//glycerol-3-phosphate O-acyltransferase 3/4 [EC:2.3.1.15];K03348//anaphase-promoting complex subunit 1;K08155//MFS transporter, DHA1 family, solute carrier family 18 (vesicular amine transporter), member 1/2","XP_002814566.2//PREDICTED: major facilitator superfamily domain-containing protein 10 [Pongo abelii];EAW82497.1//tetracycline transporter-like protein, isoform CRA_b [Homo sapiens]","1//3;4"]
[54939,805,100.15,119,0.248799152382598,0.000417291397388781,"*",1.080454E-4,"COMMD4","GO:0005634//nucleus;GO:0005737//cytoplasm","NA","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K20358//golgin subfamily A member 2","NP_001308777.1//COMM domain-containing protein 4 isoform 9 [Homo sapiens];XP_017403463.1//PREDICTED: COMM domain-containing protein 4 isoform X1 [Cebus capucinus imitator];XP_011520041.1//PREDICTED: COMM domain-containing protein 4 isoform X1 [Homo sapiens];XP_012362740.1//PREDICTED: COMM domain-containing protein 4 isoform X2 [Nomascus leucogenys];XP_017403464.1//PREDICTED: COMM domain-containing protein 4 isoform X2 [Cebus capucinus imitator]","1//3;4"]
[58500,6377,1.28,1.52,0.247927513443586,0.30467947526836,"*",0.1794622,"ZNF250","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_010628738.2//PREDICTED: zinc finger protein 250 [Fukomys damarensis]","4;3//A2MP1"]
[11092,2027,5.88,6.98,0.247410881373288,0.506956751124708,"*",0.352718,"SPACA9","GO:0005881//cytoplasmic microtubule;GO:0001669//acrosomal vesicle","GO:0048306//calcium-dependent protein binding","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K17985//activating molecule in BECN1-regulated autophagy protein 1","NP_001303826.1//sperm acrosome-associated protein 9 isoform a [Homo sapiens];NP_001303829.1//sperm acrosome-associated protein 9 isoform c [Homo sapiens];NP_061829.3//sperm acrosome-associated protein 9 isoform b [Homo sapiens]","4;1//3"]
[6303,1085,159.96,189.79,0.246692792765998,{"v":3.12334322041763e-08,"d":"3.12E-08"},"*",{"v":4.2136e-09,"d":"4.21E-09"},"SAT1","GO:0005829//cytosol;GO:0005622//intracellular","GO:0019809//spermidine binding;GO:0042802//identical protein binding;GO:0004145//diamine N-acetyltransferase activity","GO:0009447//putrescine catabolic process;GO:0001525//angiogenesis;GO:0032918//spermidine acetylation;GO:0042127//regulation of cell proliferation;GO:0046208//spermine catabolic process;GO:0006596//polyamine biosynthetic process","K00657//diamine N-acetyltransferase [EC:2.3.1.57]","AAP92609.1//Ab2-402 [Rattus norvegicus]","3//A2MP1"]
[10307,2154,4.14,4.91,0.246092256815368,0.355813915423902,"*",0.218068,"APBB3","NA","NA","NA","K04530//amyloid beta A4 precursor protein-binding family B member 2","XP_517974.4//PREDICTED: amyloid beta A4 precursor protein-binding family B member 3 isoform X4 [Pan troglodytes];XP_016809434.1//PREDICTED: amyloid beta A4 precursor protein-binding family B member 3 isoform X2 [Pan troglodytes];XP_001139279.3//PREDICTED: amyloid beta A4 precursor protein-binding family B member 3 isoform X3 [Pan troglodytes];XP_001139203.3//PREDICTED: amyloid beta A4 precursor protein-binding family B member 3 isoform X1 [Pan troglodytes]","3//A2MP1;2//1"]
[23647,3754,19.89,23.58,0.245520442146018,1.018998575E-3,"*",0.000285784,"ARFIP2","GO:0001726//ruffle;GO:0032588//trans-Golgi network membrane;GO:0005938//cell cortex;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0019904//protein domain specific binding;GO:0048365//Rac GTPase binding;GO:0070273//phosphatidylinositol-4-phosphate binding;GO:0042802//identical protein binding;GO:0030742//GTP-dependent protein binding;GO:0005525//GTP binding;GO:0045296//cadherin binding","GO:0030032//lamellipodium assembly;GO:0031529//ruffle organization;GO:0034315//regulation of Arp2/3 complex-mediated actin nucleation;GO:0006928//movement of cell or subcellular component;GO:0030036//actin cytoskeleton organization;GO:0007264//small GTPase mediated signal transduction","K20314//arfaptin","XP_004413367.1//PREDICTED: arfaptin-2 isoform X1 [Odobenus rosmarus divergens];XP_010335315.1//PREDICTED: arfaptin-2 isoform X1 [Saimiri boliviensis boliviensis];NP_001229783.1//arfaptin-2 isoform 1 [Homo sapiens];NP_001229785.1//arfaptin-2 isoform 4 [Homo sapiens]","1//3;3//A2MP1"]
[4117,3882,1.46,1.73,0.244803668756707,0.364256415526503,"*",0.224998,"MAK","GO:0072686//mitotic spindle;GO:0005929//cilium;GO:0005634//nucleus;GO:0001917//photoreceptor inner segment;GO:0005813//centrosome;GO:0001750//photoreceptor outer segment;GO:0005737//cytoplasm;GO:0030496//midbody","GO:0046872//metal ion binding;GO:0003713//transcription coactivator activity;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0004672//protein kinase activity","GO:0010468//regulation of gene expression;GO:0030154//cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006468//protein phosphorylation;GO:0006351//transcription, DNA-templated;GO:0035556//intracellular signal transduction;GO:0007283//spermatogenesis;GO:0045494//photoreceptor cell maintenance;GO:0046777//protein autophosphorylation;GO:0060271//cilium assembly;GO:0042073//intraciliary transport;GO:0007275//multicellular organism development","K08829//male germ cell-associated kinase [EC:2.7.11.22]","NP_005897.1//serine/threonine-protein kinase MAK isoform 1 [Homo sapiens];NP_001229886.1//serine/threonine-protein kinase MAK isoform 3 [Homo sapiens];NP_001229314.1//serine/threonine-protein kinase MAK isoform 2 [Homo sapiens]","1//3;2//1;5"]
[1716,1009,74.49,88.21,0.243895455141176,1.26658406491228E-3,"*",0.000361564,"DGUOK","GO:0005759//mitochondrial matrix;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005739//mitochondrion","GO:0004138//deoxyguanosine kinase activity;GO:0005524//ATP binding;GO:0019206//nucleoside kinase activity","GO:0046122//purine deoxyribonucleoside metabolic process;GO:0010977//negative regulation of neuron projection development;GO:0006468//protein phosphorylation;GO:0008617//guanosine metabolic process;GO:0046070//dGTP metabolic process;GO:0043101//purine-containing compound salvage","K00904//deoxyguanosine kinase [EC:2.7.1.113]","XP_003268725.1//PREDICTED: deoxyguanosine kinase, mitochondrial isoform X1 [Nomascus leucogenys];AAC50624.1//deoxyguanosine kinase [Homo sapiens];NP_550438.1//deoxyguanosine kinase, mitochondrial isoform a precursor [Homo sapiens];NP_550440.1//deoxyguanosine kinase, mitochondrial isoform b precursor [Homo sapiens];NP_001305788.1//deoxyguanosine kinase, mitochondrial isoform c precursor [Homo sapiens];XP_011530949.1//PREDICTED: deoxyguanosine kinase, mitochondrial isoform X1 [Homo sapiens]","1//3;2//1"]
[51659,1196,49.09,58.1,0.243108996925843,0.00248175106666667,"*",0.000750398,"GINS2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031298//replication fork protection complex;GO:0000811//GINS complex","NA","GO:0000727//double-strand break repair via break-induced replication;GO:0006260//DNA replication;GO:1902975//mitotic DNA replication initiation;GO:0006271//DNA strand elongation involved in DNA replication;GO:0032508//DNA duplex unwinding","K10733//GINS complex subunit 2","NP_057179.1//DNA replication complex GINS protein PSF2 [Homo sapiens]","2//1"]
[51367,801,27.29,32.28,0.24226818400364,0.0918375130081301,"*",0.042429,"POP5","GO:0000172//ribonuclease MRP complex;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0030681//multimeric ribonuclease P complex;GO:0005655//nucleolar ribonuclease P complex","GO:0004526//ribonuclease P activity","GO:0001682//tRNA 5'-leader removal;GO:0009249//protein lipoylation;GO:0008033//tRNA processing","K03537//ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]","NP_937845.1//ribonuclease P/MRP protein subunit POP5 isoform c [Homo sapiens];XP_017365737.1//PREDICTED: ribonuclease P/MRP protein subunit POP5 isoform X2 [Cebus capucinus imitator]","1//3;3//A2MP1"]
[107282092,1334,25.88,30.6,0.241694035587507,0.0485545116058178,"*",0.0204808,"BOLA2-SMG1P6","NA","GO:0016301//kinase activity","NA","K08873//serine/threonine-protein kinase SMG1 [EC:2.7.11.1]","NP_001307554.1//BOLA2-SMG1P6 protein isoform d [Homo sapiens];NP_001307551.1//BOLA2-SMG1P6 protein isoform a [Homo sapiens];NP_001307552.1//BOLA2-SMG1P6 protein isoform b [Homo sapiens];NP_001307553.1//BOLA2-SMG1P6 protein isoform c [Homo sapiens]","1//3"]
[7016,2463,42.04,49.69,0.241192872587931,{"v":6.00766148031496e-05,"d":"6.01E-05"},"*",{"v":1.337376e-05,"d":"1.34E-05"},"TESK1","GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0004713//protein tyrosine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0046872//metal ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0004871//signal transducer activity","GO:0035556//intracellular signal transduction;GO:0007283//spermatogenesis","K08841//testis-specific kinase 1 [EC:2.7.12.1]","NP_001305159.1//dual specificity testis-specific protein kinase 1 isoform 2 [Homo sapiens];NP_006276.2//dual specificity testis-specific protein kinase 1 isoform 1 [Homo sapiens]","1//3;2//1"]
[23203,2158,38.47,45.45,0.240546464784855,2.88133214855434E-4,"*",{"v":7.2367e-05,"d":"7.24E-05"},"PMPCA","GO:0005759//mitochondrial matrix;GO:0005615//extracellular space;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0046872//metal ion binding;GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding","GO:0006627//protein processing involved in protein targeting to mitochondrion;GO:0006851//mitochondrial calcium ion transmembrane transport;GO:0006508//proteolysis","K01412//mitochondrial-processing peptidase subunit alpha [EC:3.4.24.64]","BAA09472.2//KIAA0123, partial [Homo sapiens];NP_001269873.1//mitochondrial-processing peptidase subunit alpha isoform 2 [Homo sapiens];NP_001269875.1//mitochondrial-processing peptidase subunit alpha isoform 3 [Homo sapiens]","1//3;2//1"]
[2197,579,297.91,351.77,0.239755899087457,{"v":1.70562705018979E-7,"d":"1.71E-07"},"*",{"v":2.53164e-08,"d":"2.53E-08"},"FAU","NA","NA","NA","K02983//small subunit ribosomal protein S30e","XP_012352516.1//PREDICTED: putative ubiquitin-like protein FUBI-like protein ENSP00000310146 [Nomascus leucogenys]",4]
[3455,2178,7.95,9.38,0.238633062343659,0.0150888443491789,"*",0.00546444,"IFNAR2","GO:0005615//extracellular space;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005622//intracellular;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0019962//type I interferon binding;GO:0004905//type I interferon receptor activity;GO:0019901//protein kinase binding","GO:0035456//response to interferon-beta;GO:0060337//type I interferon signaling pathway;GO:0007259//JAK-STAT cascade;GO:0051607//defense response to virus;GO:0007166//cell surface receptor signaling pathway;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0035455//response to interferon-alpha;GO:0008283//cell proliferation;GO:0060338//regulation of type I interferon-mediated signaling pathway;GO:0009615//response to virus","K05131//interferon receptor 2","XP_009452600.1//PREDICTED: interferon alpha/beta receptor 2 isoform X3 [Pan troglodytes];XP_009452503.1//PREDICTED: interferon alpha/beta receptor 2 isoform X1 [Pan troglodytes];XP_018873344.1//PREDICTED: interferon alpha/beta receptor 2 isoform X2 [Gorilla gorilla gorilla]","4;1//3;2//1"]
[84926,2949,25.39,29.94,0.237813826410911,5.91497397701149E-4,"*",1.578536E-4,"SPRYD3","NA","NA","NA","K04967//transient receptor potential cation channel subfamily C member 4","XP_008001558.1//PREDICTED: SPRY domain-containing protein 3 [Chlorocebus sabaeus]","2//1"]
[2023,1802,1559,1838.14,0.237625724126524,{"v":8.51291026987952e-113,"d":"8.51E-113"},"*",{"v":4.42326e-115,"d":"4.42E-115"},"ENO1","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0099738//cell cortex region;GO:0005737//cytoplasm;GO:0009986//cell surface;GO:0031430//M band;GO:0005829//cytosol;GO:0000015//phosphopyruvate hydratase complex;GO:0005886//plasma membrane","GO:0000287//magnesium ion binding;GO:0003723//RNA binding;GO:0004634//phosphopyruvate hydratase activity;GO:0042803//protein homodimerization activity;GO:0001227//transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0045296//cadherin binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0051020//GTPase binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0030308//negative regulation of cell growth;GO:0061621//canonical glycolysis;GO:2001171//positive regulation of ATP biosynthetic process;GO:0006094//gluconeogenesis;GO:0006096//glycolytic process;GO:0006351//transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045933//positive regulation of muscle contraction;GO:1903298//negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway;GO:0010756//positive regulation of plasminogen activation;GO:0009615//response to virus","K01689//enolase [EC:4.2.1.11]","CAH56247.1//hypothetical protein, partial [Homo sapiens];XP_012353756.1//PREDICTED: alpha-enolase isoform X1 [Nomascus leucogenys];NP_001340275.1//alpha-enolase isoform 3 [Homo sapiens]","4;3//A2MP1;2//1"]
[29924,2484,212.92,250.83,0.236398437620636,{"v":4.74777792134831E-21,"d":"4.75E-21"},"*",{"v":2.1162e-22,"d":"2.12E-22"},"EPN1","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005905//clathrin-coated pit;GO:0005886//plasma membrane","GO:0008289//lipid binding","GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0007565//female pregnancy;GO:0006897//endocytosis;GO:0007219//Notch signaling pathway;GO:0001701//in utero embryonic development;GO:0048568//embryonic organ development;GO:0061024//membrane organization","K12471//epsin","NP_001123543.1//epsin-1 isoform a [Homo sapiens];XP_011852369.1//PREDICTED: epsin-1 isoform X1 [Mandrillus leucophaeus]","1//3;3//A2MP1"]
[6100,1184,15.11,17.8,0.236373580688931,0.141780237618809,"*",0.07097,"RP9","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005785//signal recognition particle receptor complex","GO:0003723//RNA binding;GO:0046872//metal ion binding","GO:0050890//cognition;GO:0008380//RNA splicing","K19604//retinitis pigmentosa 9 protein","EAL24464.1//similar to RP9 protein [Homo sapiens]","1//3"]
[1936,1343,319.96,376.6,0.235141442991609,{"v":1.71757021073559E-16,"d":"1.72E-16"},"*",{"v":1.08168e-17,"d":"1.08E-17"},"EEF1D","GO:0005634//nucleus;GO:0005829//cytosol;GO:0001650//fibrillar center;GO:0005853//eukaryotic translation elongation factor 1 complex;GO:0005737//cytoplasm","GO:0008135//translation factor activity, RNA binding;GO:0003677//DNA binding;GO:0031072//heat shock protein binding;GO:0003746//translation elongation factor activity;GO:0004871//signal transducer activity;GO:0033613//activating transcription factor binding;GO:0045296//cadherin binding","GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0010941//regulation of cell death;GO:0006355//regulation of transcription, DNA-templated;GO:0071479//cellular response to ionizing radiation;GO:0009299//mRNA transcription;GO:0006414//translational elongation;GO:0006351//transcription, DNA-templated","K15410//elongation factor 1-delta","BAG36963.1//unnamed protein product [Homo sapiens];XP_011732883.1//PREDICTED: LOW QUALITY PROTEIN: elongation factor 1-delta-like [Macaca nemestrina];XP_016868661.1//PREDICTED: elongation factor 1-delta isoform X6 [Homo sapiens];NP_001182132.1//elongation factor 1-delta isoform 5 [Homo sapiens];NP_115754.3//elongation factor 1-delta isoform 1 [Homo sapiens];XP_016868660.1//PREDICTED: elongation factor 1-delta isoform X5 [Homo sapiens]","1//3;3//A2MP1;2//1;5"]
[56521,1013,7.83,9.21,0.234188848800295,0.37867418258427,"*",0.236298,"DNAJC12","GO:0005737//cytoplasm","NA","NA","K09532//DnaJ homolog subfamily C member 12","NP_068572.1//dnaJ homolog subfamily C member 12 isoform a [Homo sapiens];NP_957714.1//dnaJ homolog subfamily C member 12 isoform b [Homo sapiens]","1//3;2//1"]
[728294,2653,6.15,7.23,0.233409236724516,0.192905568342951,"*",0.1025392,"D2HGDH","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0016614//oxidoreductase activity, acting on CH-OH group of donors;GO:0004458//D-lactate dehydrogenase (cytochrome) activity;GO:0050660//flavin adenine dinucleotide binding;GO:0051990//(R)-2-hydroxyglutarate dehydrogenase activity;GO:0071949//FAD binding","GO:0044267//cellular protein metabolic process;GO:0010042//response to manganese ion;GO:0032025//response to cobalt ion;GO:0022904//respiratory electron transport chain;GO:0019516//lactate oxidation;GO:0006103//2-oxoglutarate metabolic process;GO:0010043//response to zinc ion","K18204//D-2-hydroxyglutarate dehydrogenase [EC:1.1.99.39]","NP_689996.4//D-2-hydroxyglutarate dehydrogenase, mitochondrial isoform 1 precursor [Homo sapiens]","4;1//3"]
[341,588,72.37,85.02,0.232410487369321,0.0202821909926716,"*",0.00762328,"APOC1","GO:0070062//extracellular exosome;GO:0005783//endoplasmic reticulum;GO:0042627//chylomicron;GO:0034364//high-density lipoprotein particle;GO:0005576//extracellular region;GO:0034361//very-low-density lipoprotein particle","GO:0004859//phospholipase inhibitor activity;GO:0060228//phosphatidylcholine-sterol O-acyltransferase activator activity;GO:0031210//phosphatidylcholine binding;GO:0055102//lipase inhibitor activity;GO:0005504//fatty acid binding","GO:0045833//negative regulation of lipid metabolic process;GO:0010916//negative regulation of very-low-density lipoprotein particle clearance;GO:0051005//negative regulation of lipoprotein lipase activity;GO:0008203//cholesterol metabolic process;GO:0033344//cholesterol efflux;GO:0034379//very-low-density lipoprotein particle assembly;GO:0050995//negative regulation of lipid catabolic process;GO:0034382//chylomicron remnant clearance;GO:0032374//regulation of cholesterol transport;GO:0042157//lipoprotein metabolic process;GO:0010900//negative regulation of phosphatidylcholine catabolic process;GO:0032375//negative regulation of cholesterol transport;GO:0006641//triglyceride metabolic process;GO:0048261//negative regulation of receptor-mediated endocytosis;GO:0034369//plasma lipoprotein particle remodeling;GO:0045717//negative regulation of fatty acid biosynthetic process;GO:0033700//phospholipid efflux;GO:0034375//high-density lipoprotein particle remodeling;GO:0034447//very-low-density lipoprotein particle clearance;GO:0010873//positive regulation of cholesterol esterification;GO:0006629//lipid metabolic process","K22286//apolipoprotein C-I","NP_001636.1//apolipoprotein C-I precursor [Homo sapiens]","1//3;4"]
[388135,5663,0.92,1.08,0.231325546106456,0.507744692037787,"*",0.353298,"C15orf59","NA","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K01064//wingless-type MMTV integration site family, member 9","NP_001034703.1//UPF0583 protein C15orf59 isoform 1 [Homo sapiens];XP_012584239.1//PREDICTED: UPF0583 protein C15orf59 homolog isoform X1 [Condylura cristata]","1//3;2//1"]
[10555,1542,66.37,77.91,0.231277240506743,{"v":9.62937999454297e-05,"d":"9.63E-05"},"*",{"v":2.20932e-05,"d":"2.21E-05"},"AGPAT2","GO:0005783//endoplasmic reticulum;GO:0035579//specific granule membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane","GO:0016746//transferase activity, transferring acyl groups;GO:0003841//1-acylglycerol-3-phosphate O-acyltransferase activity","GO:0042493//response to drug;GO:0008152//metabolic process;GO:0001819//positive regulation of cytokine production;GO:0016024//CDP-diacylglycerol biosynthetic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0008654//phospholipid biosynthetic process;GO:0001961//positive regulation of cytokine-mediated signaling pathway;GO:0008544//epidermis development;GO:0006644//phospholipid metabolic process;GO:0043312//neutrophil degranulation","K13509//lysophosphatidate acyltransferase [EC:2.3.1.51]","NP_001012745.1//1-acyl-sn-glycerol-3-phosphate acyltransferase beta isoform b precursor [Homo sapiens];NP_006403.2//1-acyl-sn-glycerol-3-phosphate acyltransferase beta isoform a precursor [Homo sapiens]","1//3;3//A2MP1"]
[90952,1869,6.71,7.87,0.230050869307303,0.245061162966252,"*",0.138194,"ESAM","GO:0070062//extracellular exosome;GO:0016021//integral component of membrane;GO:0005923//bicellular tight junction;GO:0005886//plasma membrane;GO:0005912//adherens junction","NA","GO:0050900//leukocyte migration;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules","K06787//endothelial cell adhesion molecule","NP_620411.2//endothelial cell-selective adhesion molecule precursor [Homo sapiens]","2//1"]
[3763,2790,0.29,0.34,0.229481846122767,0.77214156438199,"*",0.67421,"KCNJ6","GO:0005887//integral component of plasma membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex","GO:0005242//inward rectifier potassium channel activity;GO:0015467//G-protein activated inward rectifier potassium channel activity","GO:0006813//potassium ion transport;GO:0010107//potassium ion import","K05000//potassium inwardly-rectifying channel subfamily J member 6","XP_007966108.1//PREDICTED: G protein-activated inward rectifier potassium channel 2 isoform X1 [Chlorocebus sabaeus]",4]
[25873,465,335.19,392.88,0.229109619078799,{"v":1.63920690749543e-06,"d":"1.64E-06"},"*",{"v":2.80658e-07,"d":"2.81E-07"},"RPL36","GO:0005840//ribosome;GO:0016020//membrane;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0022625//cytosolic large ribosomal subunit;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome","GO:0006413//translational initiation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0019083//viral transcription;GO:0006412//translation;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0002181//cytoplasmic translation;GO:0006364//rRNA processing","K02920//large subunit ribosomal protein L36e;K01530//phospholipid-translocating ATPase [EC:3.6.3.1]","XP_014996838.1//PREDICTED: probable phospholipid-transporting ATPase VB [Macaca mulatta];XP_021526953.1//rabankyrin-5 [Aotus nancymaae]","3//A2MP1;2//1"]
[29882,2733,18.7,21.91,0.228551214215223,0.00836329216011806,"*",0.0028382,"ANAPC2","GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005680//anaphase-promoting complex","GO:0031625//ubiquitin protein ligase binding","GO:0050775//positive regulation of dendrite morphogenesis;GO:0070979//protein K11-linked ubiquitination;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0045773//positive regulation of axon extension;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0051301//cell division;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0031915//positive regulation of synaptic plasticity;GO:0090129//positive regulation of synapse maturation","K03349//anaphase-promoting complex subunit 2","NP_037498.1//anaphase-promoting complex subunit 2 [Homo sapiens]","3//A2MP1"]
[10960,1853,102.93,120.54,0.227848438175637,{"v":7.06016992592593e-08,"d":"7.06E-08"},"*",{"v":1.002408E-8,"d":"1.00E-08"},"LMAN2","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0005794//Golgi apparatus;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005789//endoplasmic reticulum membrane;GO:0000139//Golgi membrane","GO:0046872//metal ion binding;GO:0030246//carbohydrate binding;GO:0031072//heat shock protein binding;GO:0005537//mannose binding","GO:0050766//positive regulation of phagocytosis;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0015031//protein transport","K10082//lectin, mannose-binding 2","NP_006807.1//vesicular integral-membrane protein VIP36 precursor [Homo sapiens]","2//1"]
[8986,3118,42.42,49.67,0.227630125906683,{"v":2.5742615904048E-5,"d":"2.57E-05"},"*",{"v":5.37446e-06,"d":"5.37E-06"},"RPS6KA4","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005737//cytoplasm","GO:0000287//magnesium ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004711//ribosomal protein S6 kinase activity","GO:0006355//regulation of transcription, DNA-templated;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction;GO:0070498//interleukin-1-mediated signaling pathway;GO:0033129//positive regulation of histone phosphorylation;GO:0006954//inflammatory response;GO:0032793//positive regulation of CREB transcription factor activity;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0043987//histone H3-S10 phosphorylation;GO:0001818//negative regulation of cytokine production;GO:0035066//positive regulation of histone acetylation;GO:0043988//histone H3-S28 phosphorylation;GO:0016572//histone phosphorylation","K16510//ribosomal protein S6 kinase alpha-4 [EC:2.7.11.1]","NP_001006945.1//ribosomal protein S6 kinase alpha-4 isoform b [Homo sapiens];NP_003933.1//ribosomal protein S6 kinase alpha-4 isoform a [Homo sapiens];NP_001287731.1//ribosomal protein S6 kinase alpha-4 isoform c [Homo sapiens]","1//3;2//1"]
[57452,3148,1.06,1.24,0.226275855823676,0.896469456644295,"*",0.836196,"GALNT16","GO:0070062//extracellular exosome;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0004653//polypeptide N-acetylgalactosaminyltransferase activity;GO:0046872//metal ion binding;GO:0030246//carbohydrate binding;GO:0016757//transferase activity, transferring glycosyl groups","GO:0006486//protein glycosylation;GO:0018242//protein O-linked glycosylation via serine;GO:0018243//protein O-linked glycosylation via threonine","K00710//polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41]","EDL02668.1//mCG7620, isoform CRA_b [Mus musculus]","1//3;2//1"]
[10715,2564,3.72,4.35,0.225712779628059,0.373342451729686,"*",0.23241,"CERS1","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0000139//Golgi membrane;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005789//endoplasmic reticulum membrane","GO:0008083//growth factor activity;GO:0005125//cytokine activity;GO:0050291//sphingosine N-acyltransferase activity;GO:0005160//transforming growth factor beta receptor binding","GO:0035690//cellular response to drug;GO:0030148//sphingolipid biosynthetic process;GO:0043408//regulation of MAPK cascade;GO:0030509//BMP signaling pathway;GO:0036146//cellular response to mycotoxin;GO:0051974//negative regulation of telomerase activity;GO:0060395//SMAD protein signal transduction;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0072721//cellular response to dithiothreitol;GO:0042981//regulation of apoptotic process;GO:0048468//cell development;GO:0071492//cellular response to UV-A;GO:0046513//ceramide biosynthetic process","K05495//growth differentiation factor 1/3;K04710//ceramide synthetase [EC:2.3.1.24]","NP_001483.3//embryonic growth/differentiation factor 1 precursor [Homo sapiens];NP_067090.1//ceramide synthase 1 isoform 1 [Homo sapiens]","4;1//3;2//1"]
[64763,3167,25.95,30.34,0.22548654700179,0.000671720764226135,"*",1.814916E-4,"ZNF574","NA","GO:0003676//nucleic acid binding","NA","K09228//KRAB domain-containing zinc finger protein","XP_021526078.1//zinc finger protein 574 isoform X2 [Aotus nancymaae]","1//3;5"]
[57060,2047,15.26,17.83,0.224551740790464,0.12847453101775,"*",0.0629826,"PCBP4","NA","NA","NA","K21444//poly(rC)-binding protein 3/4","XP_005265389.1//PREDICTED: poly(rC)-binding protein 4 isoform X3 [Homo sapiens];XP_012352205.1//PREDICTED: poly(rC)-binding protein 4 isoform X1 [Nomascus leucogenys];XP_005265387.1//PREDICTED: poly(rC)-binding protein 4 isoform X1 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[112812,864,16.62,19.41,0.223879735943319,0.232588390669508,"*",0.1298354,"FDX1L","GO:0005759//mitochondrial matrix","GO:0009055//electron transfer activity;GO:0046872//metal ion binding;GO:0051537//2 iron, 2 sulfur cluster binding","GO:0006700//C21-steroid hormone biosynthetic process;GO:0016125//sterol metabolic process;GO:0055114//oxidation-reduction process;GO:0044281//small molecule metabolic process","K22071//ferredoxin-2, mitochondrial","NP_001026904.2//ferredoxin-2, mitochondrial precursor [Homo sapiens]","3//A2MP1"]
[11015,1699,8.72,10.18,0.223337521298769,0.213436576066597,"*",0.1155636,"KDELR3","GO:0005783//endoplasmic reticulum;GO:0030133//transport vesicle;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0000139//Golgi membrane","GO:0046923//ER retention sequence binding","GO:0036498//IRE1-mediated unfolded protein response;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0015031//protein transport;GO:0006621//protein retention in ER lumen","K10949//ER lumen protein retaining receptor","NP_006846.1//ER lumen protein-retaining receptor 3 isoform a [Homo sapiens];NP_057839.1//ER lumen protein-retaining receptor 3 isoform b [Homo sapiens]","3//A2MP1;2//1"]
[25988,2323,5.51,6.43,0.22276641875679,0.186458836251483,"*",0.0984004,"HINFP","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0030054//cell junction;GO:0015030//Cajal body","GO:0042393//histone binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0003713//transcription coactivator activity;GO:0003682//chromatin binding;GO:0019899//enzyme binding;GO:0003700//DNA binding transcription factor activity","GO:0045892//negative regulation of transcription, DNA-templated;GO:0045184//establishment of protein localization;GO:0010468//regulation of gene expression;GO:0006281//DNA repair;GO:0006355//regulation of transcription, DNA-templated;GO:0000077//DNA damage checkpoint;GO:0006351//transcription, DNA-templated;GO:0010629//negative regulation of gene expression;GO:0001701//in utero embryonic development;GO:0010628//positive regulation of gene expression;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045445//myoblast differentiation;GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0000082//G1/S transition of mitotic cell cycle","K09228//KRAB domain-containing zinc finger protein","XP_003820055.1//PREDICTED: histone H4 transcription factor isoform X2 [Pan paniscus];XP_003253310.1//PREDICTED: histone H4 transcription factor isoform X1 [Nomascus leucogenys];XP_008971677.1//PREDICTED: histone H4 transcription factor isoform X1 [Pan paniscus];XP_011541046.1//PREDICTED: histone H4 transcription factor isoform X1 [Homo sapiens];NP_001230188.1//histone H4 transcription factor isoform 2 [Homo sapiens];XP_009422583.1//PREDICTED: histone H4 transcription factor isoform X1 [Pan troglodytes];NP_001338886.1//histone H4 transcription factor isoform 3 [Homo sapiens];XP_016872988.1//PREDICTED: histone H4 transcription factor isoform X3 [Homo sapiens]","4;1//3;2//1"]
[6167,1586,235.31,274.55,0.222506279016386,{"v":7.62521896563012e-14,"d":"7.63E-14"},"*",{"v":5.83324e-15,"d":"5.83E-15"},"RPL37","GO:0005840//ribosome;GO:0005829//cytosol;GO:0022625//cytosolic large ribosomal subunit","GO:0003723//RNA binding;GO:0046872//metal ion binding;GO:0019838//growth factor binding;GO:0003735//structural constituent of ribosome;GO:0019843//rRNA binding","GO:0006413//translational initiation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0019083//viral transcription;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006412//translation;GO:0006364//rRNA processing","K02922//large subunit ribosomal protein L37e","AFA34383.1//ribosomal protein L37 [Ostrea edulis]",4]
[643802,1286,0.06,0.07,0.222392421336448,1.00623301488771,"*",0.998548,"LOC643802","NA","NA","NA","K14559//U3 small nucleolar RNA-associated protein MPP10","XP_007991369.1//PREDICTED: LOW QUALITY PROTEIN: U3 small nucleolar ribonucleoprotein protein MPP10 [Chlorocebus sabaeus]","1//3"]
[79661,1724,2.77,3.23,0.221648188644736,0.526009041662949,"*",0.369102,"NEIL1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005815//microtubule organizing center;GO:0005694//chromosome;GO:0005737//cytoplasm","GO:0003906//DNA-(apurinic or apyrimidinic site) lyase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0003684//damaged DNA binding;GO:0008022//protein C-terminus binding;GO:0140078//class I DNA-(apurinic or apyrimidinic site) lyase activity;GO:0019104//DNA N-glycosylase activity;GO:0008270//zinc ion binding;GO:0140080//class III/IV DNA-(apurinic or apyrimidinic site) lyase activity","GO:0006979//response to oxidative stress;GO:0006284//base-excision repair;GO:0045008//depyrimidination;GO:0006289//nucleotide-excision repair;GO:0032074//negative regulation of nuclease activity","K10567//endonuclease VIII-like 1 [EC:3.2.2.- 4.2.99.18]","NP_001243481.1//endonuclease 8-like 1 isoform 1 [Homo sapiens];NP_001339448.1//endonuclease 8-like 1 isoform 4 [Homo sapiens];NP_001339449.1//endonuclease 8-like 1 isoform 5 [Homo sapiens];XP_011520303.2//PREDICTED: endonuclease 8-like 1 isoform X2 [Homo sapiens]","1//3;3//A2MP1"]
[9404,1926,1.75,2.04,0.221214230139167,0.557136944077805,"*",0.401652,"LPXN","GO:0016020//membrane;GO:0005634//nucleus;GO:0042995//cell projection;GO:0005925//focal adhesion;GO:0016607//nuclear speck;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0002102//podosome;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0046872//metal ion binding;GO:0003712//transcription cofactor activity","GO:0033628//regulation of cell adhesion mediated by integrin;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0006355//regulation of transcription, DNA-templated;GO:0007162//negative regulation of cell adhesion;GO:0050859//negative regulation of B cell receptor signaling pathway;GO:0006351//transcription, DNA-templated;GO:0006461//protein complex assembly","K05760//paxillin","NP_001137467.1//leupaxin isoform 1 [Homo sapiens];NP_001294880.1//leupaxin isoform 3 [Homo sapiens];NP_004802.1//leupaxin isoform 2 [Homo sapiens]","1//3;2//1"]
[25855,1430,52.75,61.46,0.220476673111052,0.00201326309301835,"*",0.000597526,"BRMS1","NA","NA","GO:0009987//cellular process","K19196//breast cancer metastasis-suppressor 1 and related proteins","XP_011842310.1//PREDICTED: breast cancer metastasis-suppressor 1 isoform X2 [Mandrillus leucophaeus];NP_001020128.1//breast cancer metastasis-suppressor 1 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[284339,1779,3.89,4.53,0.219740895060043,0.447185460489445,"*",0.29971,"TMEM145","GO:0016021//integral component of membrane","NA","GO:0007186//G-protein coupled receptor signaling pathway;GO:0019236//response to pheromone","K07188//hormone-sensitive lipase [EC:3.1.1.79]","NP_775904.2//transmembrane protein 145 precursor [Homo sapiens]","2//1"]
[4055,2222,135.86,158.16,0.219264016880844,{"v":2.14237767180174E-11,"d":"2.14E-11"},"*",{"v":2.00236E-12,"d":"2.00E-12"},"LTBR","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0042802//identical protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0005031//tumor necrosis factor-activated receptor activity","GO:0046330//positive regulation of JNK cascade;GO:0007165//signal transduction;GO:0071260//cellular response to mechanical stimulus;GO:0042127//regulation of cell proliferation;GO:0032496//response to lipopolysaccharide;GO:0016032//viral process;GO:0006954//inflammatory response;GO:0006915//apoptotic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0007275//multicellular organism development;GO:0006955//immune response;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0043011//myeloid dendritic cell differentiation","K03159//lymphotoxin beta receptor TNFR superfamily member 3","NP_001257916.1//tumor necrosis factor receptor superfamily member 3 isoform 2 [Homo sapiens];NP_002333.1//tumor necrosis factor receptor superfamily member 3 isoform 1 precursor [Homo sapiens]","1//3;2//1"]
[5524,2573,113.06,131.59,0.218961255519063,{"v":2.08520131397459e-10,"d":"2.09E-10"},"*",{"v":2.15778e-11,"d":"2.16E-11"},"PTPA","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0034704//calcium channel complex;GO:0000159//protein phosphatase type 2A complex;GO:0005737//cytoplasm","GO:0008160//protein tyrosine phosphatase activator activity;GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005524//ATP binding;GO:0046982//protein heterodimerization activity;GO:0005102//receptor binding;GO:0019888//protein phosphatase regulator activity;GO:0051721//protein phosphatase 2A binding;GO:0042803//protein homodimerization activity;GO:0016887//ATPase activity","GO:0030472//mitotic spindle organization in nucleus;GO:0043065//positive regulation of apoptotic process;GO:0035308//negative regulation of protein dephosphorylation;GO:0043666//regulation of phosphoprotein phosphatase activity;GO:0032515//negative regulation of phosphoprotein phosphatase activity;GO:0035307//positive regulation of protein dephosphorylation;GO:0032516//positive regulation of phosphoprotein phosphatase activity","K17605//serine/threonine-protein phosphatase 2A activator","EAW87881.1//protein phosphatase 2A, regulatory subunit B' (PR 53), isoform CRA_f [Homo sapiens];NP_066954.2//serine/threonine-protein phosphatase 2A activator isoform b [Homo sapiens];EAW87885.1//protein phosphatase 2A, regulatory subunit B' (PR 53), isoform CRA_j [Homo sapiens];XP_001163459.2//PREDICTED: serine/threonine-protein phosphatase 2A activator isoform X3 [Pan troglodytes];EAW87877.1//protein phosphatase 2A, regulatory subunit B' (PR 53), isoform CRA_b [Homo sapiens];XP_011517140.1//PREDICTED: serine/threonine-protein phosphatase 2A activator isoform X5 [Homo sapiens]","4;1//3;2//1"]
[27341,5455,21.72,25.27,0.218401561140414,{"v":5.8959196108291e-05,"d":"5.90E-05"},"*",{"v":1.30881e-05,"d":"1.31E-05"},"RRP7A","GO:0005654//nucleoplasm;GO:0032545//CURI complex;GO:0005737//cytoplasm;GO:0034456//UTP-C complex","GO:0003723//RNA binding","GO:0000028//ribosomal small subunit assembly;GO:0001825//blastocyst formation;GO:0006364//rRNA processing","K14545//ribosomal RNA-processing protein 7","XP_016794803.1//PREDICTED: ribosomal RNA-processing protein 7 homolog A [Pan troglodytes]",4]
[51147,1439,6.08,7.07,0.217638891365813,0.398804501112509,"*",0.258072,"ING4","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000123//histone acetyltransferase complex","GO:0046872//metal ion binding;GO:0003713//transcription coactivator activity;GO:0035064//methylated histone binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0045926//negative regulation of growth;GO:0006260//DNA replication;GO:0043981//histone H4-K5 acetylation;GO:0016573//histone acetylation;GO:0006473//protein acetylation;GO:0007050//cell cycle arrest;GO:0006915//apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0043966//histone H3 acetylation;GO:0043982//histone H4-K8 acetylation;GO:0043983//histone H4-K12 acetylation;GO:0008285//negative regulation of cell proliferation;GO:0006978//DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator","K11346//inhibitor of growth protein 4","NP_001121055.1//inhibitor of growth protein 4 isoform 3 [Homo sapiens];NP_001121056.1//inhibitor of growth protein 4 isoform 4 [Homo sapiens];NP_001121058.1//inhibitor of growth protein 4 isoform 6 [Homo sapiens];NP_057246.2//inhibitor of growth protein 4 isoform 1 [Homo sapiens];NP_001121054.1//inhibitor of growth protein 4 isoform 9 [Homo sapiens];NP_001121057.1//inhibitor of growth protein 4 isoform 5 [Homo sapiens]","1//3;3//A2MP1"]
[6139,753,547.52,636.46,0.217158182077484,{"v":1.79305928140556e-12,"d":"1.79E-12"},"*",{"v":1.533316E-13,"d":"1.53E-13"},"RPL17","NA","NA","NA","K02880//large subunit ribosomal protein L17e","XP_005983921.1//PREDICTED: 60S ribosomal protein L17-like [Pantholops hodgsonii];XP_017173407.1//PREDICTED: 60S ribosomal protein L17 isoform X1 [Mus musculus];XP_011929989.1//PREDICTED: 60S ribosomal protein L17 isoform X1 [Cercocebus atys]","4;1//3;2//1"]
[1647,1313,8.38,9.74,0.21697152838299,0.524732067845028,"*",0.367976,"GADD45A","GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0016607//nuclear speck;GO:0005737//cytoplasm","GO:0047485//protein N-terminus binding;GO:0046982//protein heterodimerization activity;GO:0019900//kinase binding;GO:0042803//protein homodimerization activity;GO:0001047//core promoter binding","GO:0046330//positive regulation of JNK cascade;GO:0007098//centrosome cycle;GO:0071260//cellular response to mechanical stimulus;GO:0006950//response to stress;GO:0007050//cell cycle arrest;GO:0000185//activation of MAPKKK activity;GO:0043065//positive regulation of apoptotic process;GO:0071850//mitotic cell cycle arrest;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0006281//DNA repair;GO:0006915//apoptotic process;GO:1900745//positive regulation of p38MAPK cascade;GO:0006469//negative regulation of protein kinase activity;GO:0042770//signal transduction in response to DNA damage;GO:0071479//cellular response to ionizing radiation;GO:0051726//regulation of cell cycle;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity","K04402//growth arrest and DNA-damage-inducible protein","NP_001186670.1//growth arrest and DNA damage-inducible protein GADD45 alpha isoform 2 [Homo sapiens];NP_001915.1//growth arrest and DNA damage-inducible protein GADD45 alpha isoform 1 [Homo sapiens];NP_001186671.1//growth arrest and DNA damage-inducible protein GADD45 alpha isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[56901,1275,1.98,2.3,0.216133430864766,0.659332779427522,"*",0.539304,"NDUFA4L2","NA","NA","NA","K03948//NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4","XP_011536875.1//PREDICTED: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 isoform X1 [Homo sapiens]","3//A2MP1"]
[8859,1622,3.78,4.39,0.215834705314285,0.497568611287254,"*",0.34385,"STK19","GO:0005634//nucleus;GO:0016607//nuclear speck","GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding","GO:0006468//protein phosphorylation","K08880//serine/threonine kinase 19 [EC:2.7.11.1]","XP_009449215.2//PREDICTED: serine/threonine-protein kinase 19 isoform X2 [Pan troglodytes]","1//3"]
[6277,683,774.05,898.51,0.215107799638313,{"v":2.59428928262712e-17,"d":"2.59E-17"},"*",{"v":1.533122E-18,"d":"1.53E-18"},"S100A6","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0001726//ruffle;GO:0005829//cytosol;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0005576//extracellular region","GO:0005523//tropomyosin binding;GO:0044548//S100 protein binding;GO:0005509//calcium ion binding;GO:0008270//zinc ion binding;GO:0015075//ion transmembrane transporter activity;GO:0048306//calcium-dependent protein binding;GO:0042803//protein homodimerization activity","GO:0007165//signal transduction;GO:0048146//positive regulation of fibroblast proliferation;GO:0007409//axonogenesis","K21128//protein S100-A9;K17274//calpactin-1 light chain","XP_008853760.1//PREDICTED: protein S100-A6 [Nannospalax galili]","3//A2MP1"]
[2297,2272,5.73,6.65,0.214819201631647,0.276820594681428,"*",0.1596562,"FOXD1","GO:0005634//nucleus","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:0043565//sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0008301//DNA binding, bending","GO:0090184//positive regulation of kidney development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0009653//anatomical structure morphogenesis;GO:0030154//cell differentiation;GO:0030513//positive regulation of BMP signaling pathway;GO:0010628//positive regulation of gene expression;GO:0072210//metanephric nephron development;GO:0072267//metanephric capsule specification;GO:0072076//nephrogenic mesenchyme development;GO:0032275//luteinizing hormone secretion;GO:0060678//dichotomous subdivision of terminal units involved in ureteric bud branching;GO:0007411//axon guidance;GO:0072213//metanephric capsule development","K09397//forkhead box protein D","NP_004463.1//forkhead box protein D1 [Homo sapiens]","2//1"]
[4350,1079,54.35,63.04,0.213987499541705,0.0129258033947045,"*",4.61474E-3,"MPG","GO:0005654//nucleoplasm;GO:0042645//mitochondrial nucleoid","GO:0003905//alkylbase DNA N-glycosylase activity;GO:0003677//DNA binding;GO:0052821//DNA-7-methyladenine glycosylase activity;GO:0008725//DNA-3-methyladenine glycosylase activity;GO:0003684//damaged DNA binding;GO:0019104//DNA N-glycosylase activity;GO:0043916//DNA-7-methylguanine glycosylase activity;GO:0052822//DNA-3-methylguanine glycosylase activity","GO:0006307//DNA dealkylation involved in DNA repair;GO:0045007//depurination;GO:0006284//base-excision repair","K03652//DNA-3-methyladenine glycosylase [EC:3.2.2.21]","NP_001015052.1//DNA-3-methyladenine glycosylase isoform b [Homo sapiens];NP_002425.2//DNA-3-methyladenine glycosylase isoform a [Homo sapiens];XP_016784459.1//PREDICTED: DNA-3-methyladenine glycosylase isoform X1 [Pan troglodytes]","3//A2MP1;2//1"]
[10067,1586,106.78,123.79,0.213253321397439,{"v":3.49264173587522e-06,"d":"3.49E-06"},"*",{"v":6.30792e-07,"d":"6.31E-07"},"SCAMP3","GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0016021//integral component of membrane","GO:0031625//ubiquitin protein ligase binding","GO:0006892//post-Golgi vesicle-mediated transport;GO:0015031//protein transport","K19995//secretory carrier-associated membrane protein","NP_005689.2//secretory carrier-associated membrane protein 3 isoform 1 [Homo sapiens];NP_443069.1//secretory carrier-associated membrane protein 3 isoform 2 [Homo sapiens]","3//A2MP1;2//1"]
[8448,2091,11.74,13.6,0.21217424302765,0.10325152173913,"*",0.048465,"DOC2A","NA","NA","NA","K19916//double C2-like domain-containing protein alpha","XP_004057516.2//PREDICTED: double C2-like domain-containing protein alpha isoform X1 [Gorilla gorilla gorilla]","1//3;2//1"]
[23327,8367,3.48,4.03,0.211692532679239,0.0773073928651059,"*",0.0347288,"NEDD4L","GO:0070062//extracellular exosome;GO:0005654//nucleoplasm;GO:0005622//intracellular;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0005771//multivesicular body;GO:0005886//plasma membrane","GO:0061630//ubiquitin protein ligase activity;GO:0015459//potassium channel regulator activity;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0019871//sodium channel inhibitor activity;GO:0044325//ion channel binding;GO:0019870//potassium channel inhibitor activity;GO:0017080//sodium channel regulator activity","GO:0070936//protein K48-linked ubiquitination;GO:0034220//ion transmembrane transport;GO:0016567//protein ubiquitination;GO:1901380//negative regulation of potassium ion transmembrane transport;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0045807//positive regulation of endocytosis;GO:0019058//viral life cycle;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:1901017//negative regulation of potassium ion transmembrane transporter activity;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0003254//regulation of membrane depolarization;GO:1902306//negative regulation of sodium ion transmembrane transport;GO:0006883//cellular sodium ion homeostasis;GO:2000650//negative regulation of sodium ion transmembrane transporter activity;GO:0006814//sodium ion transport;GO:0010038//response to metal ion;GO:0042391//regulation of membrane potential;GO:0000209//protein polyubiquitination;GO:0086005//ventricular cardiac muscle cell action potential;GO:2000009//negative regulation of protein localization to cell surface;GO:0006513//protein monoubiquitination;GO:0030104//water homeostasis;GO:0034765//regulation of ion transmembrane transport;GO:0007588//excretion;GO:2001288//positive regulation of caveolin-mediated endocytosis;GO:1901016//regulation of potassium ion transmembrane transporter activity;GO:1903861//positive regulation of dendrite extension;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0042176//regulation of protein catabolic process;GO:0060306//regulation of membrane repolarization;GO:0045732//positive regulation of protein catabolic process","K13305//E3 ubiquitin-protein ligase NEDD4-like [EC:2.3.2.26]","NP_001138441.1//E3 ubiquitin-protein ligase NEDD4-like isoform 5 [Homo sapiens];NP_056092.2//E3 ubiquitin-protein ligase NEDD4-like isoform 3 [Homo sapiens];NP_001138439.1//E3 ubiquitin-protein ligase NEDD4-like isoform 1 [Homo sapiens];NP_001138440.1//E3 ubiquitin-protein ligase NEDD4-like isoform 4 [Homo sapiens];XP_011524189.1//PREDICTED: E3 ubiquitin-protein ligase NEDD4-like isoform X10 [Homo sapiens];NP_001230889.1//E3 ubiquitin-protein ligase NEDD4-like isoform 7 [Homo sapiens];EHH29321.1//hypothetical protein EGK_09715, partial [Macaca mulatta]","1//3;2//1;5"]
[171024,5617,0.95,1.1,0.211504105193712,0.890241861303558,"*",0.828548,"SYNPO2","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005925//focal adhesion;GO:0001725//stress fiber;GO:0030018//Z disc;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0099023//tethering complex","GO:0003779//actin binding;GO:0071889//14-3-3 protein binding;GO:0051393//alpha-actinin binding;GO:0031005//filamin binding;GO:0051371//muscle alpha-actinin binding","GO:2000298//regulation of Rho-dependent protein serine/threonine kinase activity;GO:0030335//positive regulation of cell migration;GO:0032233//positive regulation of actin filament bundle assembly;GO:0000045//autophagosome assembly","K12581//CCR4-NOT transcription complex subunit 7/8;K06245//laminin, beta 4;K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K02927//large subunit ribosomal protein L40e;K21112//synaptopodin;K12025//tripartite motif-containing protein 52","AAI50630.1//Synaptopodin 2 [Homo sapiens];NP_001122406.1//synaptopodin-2 isoform c [Homo sapiens];NP_001273683.1//synaptopodin-2 isoform d [Homo sapiens];NP_597734.2//synaptopodin-2 isoform a [Homo sapiens];NP_001122405.1//synaptopodin-2 isoform b [Homo sapiens]","1//3;2//1"]
[55831,2660,22.18,25.67,0.210823930413709,0.00878094653196179,"*",0.00299258,"EMC3","GO:0072546//ER membrane protein complex;GO:0016021//integral component of membrane","NA","GO:0034975//protein folding in endoplasmic reticulum","K12581//CCR4-NOT transcription complex subunit 7/8;K01064//wingless-type MMTV integration site family, member 9;K12025//tripartite motif-containing protein 52","EDK99483.1//mCG132973, isoform CRA_a, partial [Mus musculus]","3//A2MP1"]
[51763,3133,16.58,19.18,0.21015871352238,0.0202530522138931,"*",0.00761106,"INPP5K","GO:0016020//membrane;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0032587//ruffle membrane;GO:0005802//trans-Golgi network;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0043005//neuron projection;GO:0001726//ruffle;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0005000//vasopressin receptor activity;GO:0004445//inositol-polyphosphate 5-phosphatase activity;GO:0034485//phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity;GO:0046030//inositol trisphosphate phosphatase activity;GO:0042577//lipid phosphatase activity;GO:0052659//inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity;GO:0016787//hydrolase activity;GO:0004439//phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity;GO:0034595//phosphatidylinositol phosphate 5-phosphatase activity;GO:0034594//phosphatidylinositol trisphosphate phosphatase activity;GO:0016312//inositol bisphosphate phosphatase activity;GO:0052658//inositol-1,4,5-trisphosphate 5-phosphatase activity","GO:0043407//negative regulation of MAP kinase activity;GO:0006661//phosphatidylinositol biosynthetic process;GO:0071356//cellular response to tumor necrosis factor;GO:0042593//glucose homeostasis;GO:0097178//ruffle assembly;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0043922//negative regulation by host of viral transcription;GO:0051898//negative regulation of protein kinase B signaling;GO:0045892//negative regulation of transcription, DNA-templated;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0030036//actin cytoskeleton organization;GO:0001933//negative regulation of protein phosphorylation;GO:0046855//inositol phosphate dephosphorylation;GO:0045719//negative regulation of glycogen biosynthetic process;GO:0010801//negative regulation of peptidyl-threonine phosphorylation;GO:0035305//negative regulation of dephosphorylation;GO:0071320//cellular response to cAMP;GO:0051926//negative regulation of calcium ion transport;GO:0045869//negative regulation of single stranded viral RNA replication via double stranded DNA intermediate;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051497//negative regulation of stress fiber assembly;GO:0016311//dephosphorylation;GO:0007186//G-protein coupled receptor signaling pathway;GO:0072659//protein localization to plasma membrane;GO:0090315//negative regulation of protein targeting to membrane;GO:2000466//negative regulation of glycogen (starch) synthase activity;GO:0001701//in utero embryonic development;GO:0032870//cellular response to hormone stimulus;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0032869//cellular response to insulin stimulus;GO:0006469//negative regulation of protein kinase activity;GO:2001153//positive regulation of renal water transport;GO:0005979//regulation of glycogen biosynthetic process;GO:0010829//negative regulation of glucose transport;GO:0035810//positive regulation of urine volume;GO:0046856//phosphatidylinositol dephosphorylation","K01106//inositol-1,4,5-trisphosphate 5-phosphatase [EC:3.1.3.56]","NP_057616.2//inositol polyphosphate 5-phosphatase K isoform 1 [Homo sapiens];EAW90617.1//skeletal muscle and kidney enriched inositol phosphatase, isoform CRA_d [Homo sapiens]","1//3;3//A2MP1;2//1"]
[7051,2777,0.32,0.37,0.20945336562895,0.780496302939711,"*",0.68644,"TGM1","GO:0031224//intrinsic component of membrane;GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0001533//cornified envelope;GO:0005886//plasma membrane","GO:0046872//metal ion binding;GO:0003810//protein-glutamine gamma-glutamyltransferase activity","GO:0018149//peptide cross-linking;GO:0043163//cell envelope organization;GO:0006464//cellular protein modification process;GO:0030216//keratinocyte differentiation;GO:0010838//positive regulation of keratinocyte proliferation;GO:0045787//positive regulation of cell cycle;GO:0070268//cornification","K05619//transglutaminase 1 [EC:2.3.2.13]","NP_000350.1//protein-glutamine gamma-glutamyltransferase K [Homo sapiens]","2//1"]
[11199,1447,10.08,11.65,0.208834316041726,0.262499539054291,"*",0.1501312,"ANXA10","GO:0005739//mitochondrion","GO:0005544//calcium-dependent phospholipid binding;GO:0005509//calcium ion binding","NA","K17097//annexin A10","NP_009124.2//annexin A10 [Homo sapiens]",4]
[114787,4208,7.55,8.72,0.207851490564485,0.0730601378071038,"*",0.0325784,"GPRIN1","GO:0030426//growth cone;GO:0005886//plasma membrane","GO:0051219//phosphoprotein binding","GO:0031175//neuron projection development","K22020//mucin-19;K03626//nascent polypeptide-associated complex subunit alpha","NP_443131.2//G protein-regulated inducer of neurite outgrowth 1 [Homo sapiens]","2//1"]
[410,4187,10.47,12.08,0.20635901239427,0.0392570611987189,"*",0.01611422,"ARSA","GO:0070062//extracellular exosome;GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0031232//extrinsic component of external side of plasma membrane;GO:0001669//acrosomal vesicle;GO:0005764//lysosome;GO:0005768//endosome;GO:0035578//azurophil granule lumen;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0043202//lysosomal lumen","GO:0008484//sulfuric ester hydrolase activity;GO:0004098//cerebroside-sulfatase activity;GO:0005509//calcium ion binding;GO:0004065//arylsulfatase activity","GO:0043687//post-translational protein modification;GO:0008152//metabolic process;GO:0009268//response to pH;GO:0043627//response to estrogen;GO:0007417//central nervous system development;GO:0045471//response to ethanol;GO:0007339//binding of sperm to zona pellucida;GO:0006687//glycosphingolipid metabolic process;GO:0051597//response to methylmercury;GO:0007584//response to nutrient;GO:0043312//neutrophil degranulation;GO:0006914//autophagy","K01134//arylsulfatase A [EC:3.1.6.8]","NP_000478.3//arylsulfatase A isoform a precursor [Homo sapiens]","2//1;5"]
[120227,1633,5.74,6.62,0.20578048013153,0.391976538605292,"*",0.249482,"CYP2R1","GO:0031090//organelle membrane;GO:0005789//endoplasmic reticulum membrane","GO:0008395//steroid hydroxylase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0020037//heme binding;GO:0005506//iron ion binding;GO:0004497//monooxygenase activity;GO:0030343//vitamin D3 25-hydroxylase activity","GO:0006766//vitamin metabolic process;GO:0010212//response to ionizing radiation;GO:0010164//response to cesium ion;GO:0042359//vitamin D metabolic process","K07419//vitamin D 25-hydroxylase [EC:1.14.14.24]","NP_078790.2//vitamin D 25-hydroxylase [Homo sapiens]",4]
[10005,1188,10.25,11.82,0.205606125784724,0.323805108345534,"*",0.193829,"ACOT8","GO:0005782//peroxisomal matrix;GO:0005739//mitochondrion","GO:0033882//choloyl-CoA hydrolase activity;GO:0047617//acyl-CoA hydrolase activity;GO:0016289//CoA hydrolase activity;GO:0052815//medium-chain acyl-CoA hydrolase activity;GO:0052689//carboxylic ester hydrolase activity;GO:0016290//palmitoyl-CoA hydrolase activity;GO:0005102//receptor binding;GO:0003986//acetyl-CoA hydrolase activity","GO:0045225//negative regulation of CD4 biosynthetic process;GO:0033540//fatty acid beta-oxidation using acyl-CoA oxidase;GO:0043649//dicarboxylic acid catabolic process;GO:0016032//viral process;GO:0036109//alpha-linolenic acid metabolic process;GO:0009062//fatty acid catabolic process;GO:0006637//acyl-CoA metabolic process;GO:0006699//bile acid biosynthetic process;GO:0016559//peroxisome fission","K11992//acyl-CoA thioesterase 8 [EC:3.1.2.27]","NP_005460.2//acyl-coenzyme A thioesterase 8 [Homo sapiens]","3//A2MP1"]
[2950,986,504.43,581.3,0.204628828850972,{"v":3.65707744072398e-15,"d":"3.66E-15"},"*",{"v":2.52978e-16,"d":"2.53E-16"},"GSTP1","GO:0097057//TRAF2-GSTP1 complex;GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0005622//intracellular;GO:0031982//vesicle;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005576//extracellular region;GO:1904813//ficolin-1-rich granule lumen;GO:0005739//mitochondrion;GO:0005886//plasma membrane","GO:0004364//glutathione transferase activity;GO:0035730//S-nitrosoglutathione binding;GO:0008432//JUN kinase binding;GO:0004602//glutathione peroxidase activity;GO:0070026//nitric oxide binding;GO:0019901//protein kinase binding;GO:0008144//drug binding;GO:0043295//glutathione binding;GO:0019207//kinase regulator activity;GO:0035731//dinitrosyl-iron complex binding","GO:0032930//positive regulation of superoxide anion generation;GO:0031100//animal organ regeneration;GO:0032872//regulation of stress-activated MAPK cascade;GO:0010804//negative regulation of tumor necrosis factor-mediated signaling pathway;GO:0043407//negative regulation of MAP kinase activity;GO:0071222//cellular response to lipopolysaccharide;GO:0032691//negative regulation of interleukin-1 beta production;GO:0071672//negative regulation of smooth muscle cell chemotaxis;GO:0045471//response to ethanol;GO:0032355//response to estradiol;GO:0014003//oligodendrocyte development;GO:0002674//negative regulation of acute inflammatory response;GO:0033591//response to L-ascorbic acid;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0035732//nitric oxide storage;GO:0006805//xenobiotic metabolic process;GO:0070664//negative regulation of leukocyte proliferation;GO:0043066//negative regulation of apoptotic process;GO:0048147//negative regulation of fibroblast proliferation;GO:0032873//negative regulation of stress-activated MAPK cascade;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0035726//common myeloid progenitor cell proliferation;GO:0006749//glutathione metabolic process;GO:0034599//cellular response to oxidative stress;GO:0071460//cellular response to cell-matrix adhesion;GO:0043200//response to amino acid;GO:0071385//cellular response to glucocorticoid stimulus;GO:0032720//negative regulation of tumor necrosis factor production;GO:0051771//negative regulation of nitric-oxide synthase biosynthetic process;GO:0009636//response to toxic substance;GO:0000302//response to reactive oxygen species;GO:0043651//linoleic acid metabolic process;GO:0043508//negative regulation of JUN kinase activity;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:0043312//neutrophil degranulation;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:1901687//glutathione derivative biosynthetic process;GO:1904706//negative regulation of vascular smooth muscle cell proliferation;GO:0009890//negative regulation of biosynthetic process;GO:0071638//negative regulation of monocyte chemotactic protein-1 production;GO:0007417//central nervous system development;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0032869//cellular response to insulin stimulus;GO:0043409//negative regulation of MAPK cascade;GO:0006469//negative regulation of protein kinase activity","K00799//glutathione S-transferase [EC:2.5.1.18]","NP_000843.1//glutathione S-transferase P [Homo sapiens]","3//A2MP1"]
[6222,549,634.23,730.88,0.204628435187177,{"v":1.86174249367397E-10,"d":"1.86E-10"},"*",{"v":1.916054E-11,"d":"1.92E-11"},"RPS18","GO:0016020//membrane;GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005925//focal adhesion;GO:0022627//cytosolic small ribosomal subunit","GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome","GO:0006412//translation","K02964//small subunit ribosomal protein S18e","XP_003271942.1//PREDICTED: 40S ribosomal protein S18 [Nomascus leucogenys]","2//1"]
[10446,3207,4.61,5.31,0.203945110374815,0.271556956970291,"*",0.1562124,"LRRN2","GO:0005615//extracellular space;GO:0016021//integral component of membrane;GO:0005578//proteinaceous extracellular matrix","GO:0004872//receptor activity","GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007409//axonogenesis","K19511//peroxidase [EC:1.11.1.7];K12655//OTU domain-containing protein 5 [EC:3.4.19.12];K16351//netrin-G2 ligand","NP_006329.2//leucine-rich repeat neuronal protein 2 precursor [Homo sapiens]","1//3;2//1"]
[79149,2029,2.78,3.2,0.202987022163855,0.600625109754029,"*",0.443306,"ZSCAN5A","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein;K09229//KRAB and SCAN domains-containing zinc finger protein;K09230//SCAN domain-containing zinc finger protein","XP_010385348.1//PREDICTED: zinc finger and SCAN domain-containing protein 5A isoform X3 [Rhinopithecus roxellana];XP_010385345.1//PREDICTED: zinc finger and SCAN domain-containing protein 5A isoform X1 [Rhinopithecus roxellana];XP_010385347.1//PREDICTED: zinc finger and SCAN domain-containing protein 5A isoform X2 [Rhinopithecus roxellana];XP_011750249.1//PREDICTED: zinc finger and SCAN domain-containing protein 5A isoform X3 [Macaca nemestrina]","1//3;2//1"]
[85455,5048,0.53,0.61,0.202816882999687,0.673781283242259,"*",0.555762,"DISP2","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","NA","GO:0007224//smoothened signaling pathway","K10649//tripartite motif-containing protein 9/67;K21245//transcription factor SPT20 homolog;K04490//transcription factor 7-like 1","EAW92408.1//dispatched homolog 2 (Drosophila), isoform CRA_b, partial [Homo sapiens]","2//1"]
[342850,4748,0.2,0.23,0.20163386116965,0.788021286078099,"*",0.69735,"ANKRD62","NA","NA","NA","K17299//POTE ankyrin domain family protein","NP_001264262.1//ankyrin repeat domain-containing protein 62 [Homo sapiens]","1//3"]
[100271849,1472,8.43,9.69,0.200964034472999,0.331354527931681,"*",0.1991778,"MEF2B","NA","NA","NA","K09261//MADS-box transcription enhancer factor 2B","XP_011846106.1//PREDICTED: myocyte-specific enhancer factor 2B-like isoform X1 [Mandrillus leucophaeus]","1//3"]
[6650,4759,27.79,31.94,0.200798478210671,1.01259797881011E-4,"*",{"v":2.3334e-05,"d":"2.33E-05"},"CAPN15","GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0004198//calcium-dependent cysteine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0003700//DNA binding transcription factor activity","NA","K08582//calpain-15 [EC:3.4.22.-]","XP_011520928.1//PREDICTED: calpain-15 isoform X2 [Homo sapiens]","2//1"]
[2171,751,101.3,116.34,0.199713035139448,0.00592070767501434,"*",1.938852E-3,"FABP5","GO:0070062//extracellular exosome;GO:0030667//secretory granule membrane;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0035578//azurophil granule lumen;GO:0005829//cytosol;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0008289//lipid binding;GO:0005504//fatty acid binding;GO:0005215//transporter activity","GO:0019433//triglyceride catabolic process;GO:0006006//glucose metabolic process;GO:0015758//glucose transport;GO:0008544//epidermis development;GO:0043312//neutrophil degranulation;GO:0006656//phosphatidylcholine biosynthetic process;GO:0006629//lipid metabolic process","K08754//fatty acid-binding protein 5, epidermal","XP_011910842.1//PREDICTED: fatty acid-binding protein, epidermal [Cercocebus atys]","2//1"]
[9513,3016,40.94,47,0.199149654428951,0.000216676569635111,"*",{"v":5.31586e-05,"d":"5.32E-05"},"FXR2","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005844//polysome","GO:0003729//mRNA binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity","GO:0017148//negative regulation of translation","K15516//fragile X mental retardation protein","XP_006151848.2//PREDICTED: fragile X mental retardation syndrome-related protein 2 [Tupaia chinensis]","3//A2MP1"]
[1209,2502,163.71,187.91,0.198899395108898,{"v":3.02748185147801E-12,"d":"3.03E-12"},"*",{"v":2.62872e-13,"d":"2.63E-13"},"CLPTM1","GO:0016020//membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0016021//integral component of membrane","NA","GO:0033081//regulation of T cell differentiation in thymus;GO:0030154//cell differentiation;GO:0007275//multicellular organism development","K22016//mucin-3/17","NP_001285.1//cleft lip and palate transmembrane protein 1 isoform 2 [Homo sapiens];XP_007995351.1//PREDICTED: cleft lip and palate transmembrane protein 1 isoform X1 [Chlorocebus sabaeus];NP_001269104.1//cleft lip and palate transmembrane protein 1 isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[55101,1605,97.27,111.57,0.197882330867935,{"v":1.7088905826087E-5,"d":"1.71E-05"},"*",{"v":3.44474e-06,"d":"3.44E-06"},"DMAC2","GO:0005739//mitochondrion","NA","GO:0032981//mitochondrial respiratory chain complex I assembly","K18490//homeobox protein OTX2;K07554//ATP synthase, H+ transporting, mitochondrial F0 complex, subunit s;K14816//pre-60S factor REI1","NP_060505.2//distal membrane-arm assembly complex protein 2 isoform 4 [Homo sapiens];NP_001307769.1//distal membrane-arm assembly complex protein 2 isoform 9 [Homo sapiens];NP_001307767.1//distal membrane-arm assembly complex protein 2 isoform 7 [Homo sapiens];NP_001161342.1//distal membrane-arm assembly complex protein 2 isoform 6 [Homo sapiens];NP_001161339.1//distal membrane-arm assembly complex protein 2 isoform 1 [Homo sapiens];NP_001307768.1//distal membrane-arm assembly complex protein 2 isoform 8 [Homo sapiens];NP_001161340.1//distal membrane-arm assembly complex protein 2 isoform 2 [Homo sapiens];NP_001307770.1//distal membrane-arm assembly complex protein 2 isoform 10 [Homo sapiens];NP_001161341.1//distal membrane-arm assembly complex protein 2 isoform 3 [Homo sapiens];NP_001307773.1//distal membrane-arm assembly complex protein 2 isoform 11 [Homo sapiens];NP_001161343.1//distal membrane-arm assembly complex protein 2 isoform 5 [Homo sapiens]","1//3;2//1"]
[23582,3669,5.47,6.27,0.196924610009482,0.200175638490389,"*",0.1069174,"CCNDBP1","GO:0005654//nucleoplasm","NA","GO:0051726//regulation of cell cycle","K21626//cyclin-D1-binding protein 1","XP_011796513.1//PREDICTED: cyclin-D1-binding protein 1 isoform X2 [Colobus angolensis palliatus]",4]
[26284,1923,66.84,76.59,0.196444305067087,0.000207922298847041,"*",{"v":5.08026E-5,"d":"5.08E-05"},"ERAL1","GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0003723//RNA binding;GO:0043024//ribosomal small subunit binding;GO:0005525//GTP binding;GO:0019843//rRNA binding","GO:0000028//ribosomal small subunit assembly;GO:0070126//mitochondrial translational termination;GO:0070125//mitochondrial translational elongation","K03595//GTPase","AAG12978.1//ERA-W, partial [Homo sapiens];NP_001304915.1//GTPase Era, mitochondrial isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[2946,1478,5.09,5.83,0.195830227124801,0.587965762659847,"*",0.431754,"GSTM2","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0016529//sarcoplasmic reticulum","GO:0004364//glutathione transferase activity;GO:0043295//glutathione binding;GO:0004602//glutathione peroxidase activity;GO:0005102//receptor binding;GO:0042803//protein homodimerization activity;GO:0019899//enzyme binding","GO:0042178//xenobiotic catabolic process;GO:0014809//regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion;GO:0008152//metabolic process;GO:0043651//linoleic acid metabolic process;GO:0070458//cellular detoxification of nitrogen compound;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0006749//glutathione metabolic process;GO:0071313//cellular response to caffeine;GO:0055119//relaxation of cardiac muscle;GO:0060316//positive regulation of ryanodine-sensitive calcium-release channel activity;GO:0010881//regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion;GO:0060315//negative regulation of ryanodine-sensitive calcium-release channel activity;GO:0018916//nitrobenzene metabolic process;GO:1901687//glutathione derivative biosynthetic process","K00799//glutathione S-transferase [EC:2.5.1.18]","NP_000839.1//glutathione S-transferase Mu 2 isoform 1 [Homo sapiens];NP_001135840.1//glutathione S-transferase Mu 2 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[51371,1477,45.96,52.59,0.194409698834581,0.0108458702762827,"*",0.00378458,"POMP","GO:0000502//proteasome complex","NA","GO:0043248//proteasome assembly","K11599//proteasome maturation protein","XP_004854854.2//proteasome maturation protein [Heterocephalus glaber]",5]
[54923,1452,10.37,11.86,0.193688115732778,0.22707950356653,"*",0.1243578,"LIME1","GO:0019815//B cell receptor complex;GO:0005615//extracellular space;GO:0071008//U2-type post-mRNA release spliceosomal complex;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0019901//protein kinase binding","GO:0050853//B cell receptor signaling pathway;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0014066//regulation of phosphatidylinositol 3-kinase signaling;GO:0050852//T cell receptor signaling pathway;GO:0051279//regulation of release of sequestered calcium ion into cytosol;GO:0042345//regulation of NF-kappaB import into nucleus;GO:0043405//regulation of MAP kinase activity;GO:0000390//spliceosomal complex disassembly;GO:0002250//adaptive immune response","K16628//collagen, type VII, alpha;K06237//collagen, type IV, alpha;K19721//collagen, type V/XI/XXIV/XXVII, alpha;K19720//collagen, type III, alpha","XP_014198608.1//PREDICTED: lck-interacting transmembrane adapter 1 isoform X4 [Pan paniscus];NP_060276.2//lck-interacting transmembrane adapter 1 isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[57130,3887,20.61,23.56,0.192995034291204,0.00487302061143524,"*",0.001568616,"ATP13A1","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0046872//metal ion binding;GO:0005524//ATP binding;GO:0005388//calcium-transporting ATPase activity;GO:0016887//ATPase activity;GO:0015410//manganese-transporting ATPase activity","GO:0034220//ion transmembrane transport;GO:0006812//cation transport;GO:0006874//cellular calcium ion homeostasis","K14950//manganese-transporting P-type ATPase [EC:3.6.3.-]","NP_065143.2//manganese-transporting ATPase 13A1 [Homo sapiens]","2//1"]
[57463,5174,0.35,0.4,0.192645077942396,0.765521287911456,"*",0.6668,"AMIGO1","GO:0030425//dendrite;GO:0030424//axon;GO:0005887//integral component of plasma membrane;GO:0032809//neuronal cell body membrane;GO:0008076//voltage-gated potassium channel complex;GO:0043204//perikaryon","GO:0015459//potassium channel regulator activity","GO:0042552//myelination;GO:0007413//axonal fasciculation;GO:1901381//positive regulation of potassium ion transmembrane transport;GO:0050772//positive regulation of axonogenesis;GO:0051965//positive regulation of synapse assembly;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007409//axonogenesis;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules","K19511//peroxidase [EC:1.11.1.7]","OWK04833.1//AMIGO1 [Cervus elaphus hippelaphus]","3//A2MP1"]
[506,1857,432.36,494.03,0.192365594610411,{"v":1.01299377142857E-21,"d":"1.01E-21"},"*",{"v":4.35028e-23,"d":"4.35E-23"},"ATP5F1B","GO:0005759//mitochondrial matrix;GO:0016020//membrane;GO:0042645//mitochondrial nucleoid;GO:0005754//mitochondrial proton-transporting ATP synthase, catalytic core;GO:0045259//proton-transporting ATP synthase complex;GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0070062//extracellular exosome;GO:0031012//extracellular matrix;GO:0045261//proton-transporting ATP synthase complex, catalytic core F(1);GO:0005634//nucleus;GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0043209//myelin sheath;GO:0009986//cell surface;GO:0005743//mitochondrial inner membrane;GO:0031966//mitochondrial membrane","GO:0005524//ATP binding;GO:0043532//angiostatin binding;GO:0042288//MHC class I protein binding;GO:0005215//transporter activity;GO:0022857//transmembrane transporter activity;GO:0046961//proton-transporting ATPase activity, rotational mechanism;GO:0046933//proton-transporting ATP synthase activity, rotational mechanism","GO:0001649//osteoblast differentiation;GO:0042407//cristae formation;GO:0001525//angiogenesis;GO:0042776//mitochondrial ATP synthesis coupled proton transport;GO:0006091//generation of precursor metabolites and energy;GO:0051453//regulation of intracellular pH;GO:0006933//negative regulation of cell adhesion involved in substrate-bound cell migration;GO:0007005//mitochondrion organization;GO:0015986//ATP synthesis coupled proton transport;GO:0006754//ATP biosynthetic process;GO:0015992//proton transport;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0006629//lipid metabolic process","K02133//F-type H+-transporting ATPase subunit beta [EC:3.6.3.14]","NP_001677.2//ATP synthase subunit beta, mitochondrial precursor [Homo sapiens]","3//A2MP1"]
[5947,1418,1.41,1.61,0.191365525715823,0.681429970176368,"*",0.563564,"RBP1","GO:0044297//cell body;GO:0005654//nucleoplasm;GO:0005829//cytosol","GO:0008289//lipid binding;GO:0016918//retinal binding;GO:0005215//transporter activity;GO:0019841//retinol binding;GO:0005501//retinoid binding","GO:0001523//retinoid metabolic process;GO:0042572//retinol metabolic process;GO:0002138//retinoic acid biosynthetic process;GO:0006776//vitamin A metabolic process;GO:0033189//response to vitamin A;GO:0030852//regulation of granulocyte differentiation","K11447//histone demethylase [EC:1.14.11.-];K06210//nicotinamide mononucleotide adenylyltransferase [EC:2.7.7.1 2.7.7.18];K14622//retinol binding protein 2","NP_002890.2//retinol-binding protein 1 isoform a [Homo sapiens];NP_001124465.1//retinol-binding protein 1 isoform c [Homo sapiens];NP_001124464.1//retinol-binding protein 1 isoform b [Homo sapiens]","1//3;3//A2MP1"]
[286257,828,39.26,44.81,0.190760553686334,0.112776020734908,"*",0.053797,"PAXX","GO:0043564//Ku70:Ku80 complex;GO:0035861//site of double-strand break;GO:0070419//nonhomologous end joining complex;GO:0070062//extracellular exosome;GO:0005634//nucleus","GO:0032947//protein complex scaffold activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity","GO:0051103//DNA ligation involved in DNA repair;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0006974//cellular response to DNA damage stimulus","NA","NP_001316607.1//protein PAXX isoform 1 [Homo sapiens];NP_899064.1//protein PAXX isoform 2 [Homo sapiens]","1//3;2//1"]
[6560,4692,8.72,9.95,0.190368390654084,0.0737280137911703,"*",0.0329316,"SLC12A4","GO:0016021//integral component of membrane","GO:0015379//potassium:chloride symporter activity","NA","K14427//solute carrier family 12 (potassium/chloride transporter), member 4/5/6","XP_012516013.1//PREDICTED: solute carrier family 12 member 4 isoform X1 [Propithecus coquereli];XP_012323591.1//solute carrier family 12 member 4 isoform X3 [Aotus nancymaae];XP_008063936.1//solute carrier family 12 member 4 isoform X1 [Carlito syrichta];XP_012323590.1//solute carrier family 12 member 4 isoform X2 [Aotus nancymaae]","4;1//3"]
[2116,1087,1.21,1.38,0.189661219503575,0.652897259045578,"*",0.495906,"ETV2","GO:0005634//nucleus","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:2000382//positive regulation of mesoderm development;GO:0030154//cell differentiation;GO:0001890//placenta development;GO:0045603//positive regulation of endothelial cell differentiation;GO:0030218//erythrocyte differentiation;GO:0060803//BMP signaling pathway involved in mesodermal cell fate specification;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0001824//blastocyst development;GO:0048514//blood vessel morphogenesis;GO:0016055//Wnt signaling pathway;GO:0007219//Notch signaling pathway","K09432//ETS translocation variant 2","NP_001291478.1//ETS translocation variant 2 isoform 3 [Homo sapiens];XP_005258709.1//PREDICTED: ETS translocation variant 2 isoform X1 [Homo sapiens];NP_055024.2//ETS translocation variant 2 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[5937,4300,14.67,16.73,0.189568574364963,0.0150876169305219,"*",0.00546494,"RBMS1","NA","NA","NA","K03344//Dvl-binding protein IDAX;K20638//Rho GTPase-activating protein 17","XP_016289148.1//PREDICTED: RNA-binding motif, single-stranded-interacting protein 1 isoform X3 [Monodelphis domestica];XP_006766541.1//PREDICTED: RNA-binding motif, single-stranded-interacting protein 1 [Myotis davidii]","4;3//A2MP1"]
[83549,2196,11.43,13.03,0.189011680353656,0.162772398637967,"*",0.083791,"UCK1","GO:0005829//cytosol","GO:0004849//uridine kinase activity;GO:0005524//ATP binding;GO:0019206//nucleoside kinase activity","GO:0043097//pyrimidine nucleoside salvage;GO:0006206//pyrimidine nucleobase metabolic process;GO:0044206//UMP salvage;GO:0044211//CTP salvage","K00876//uridine kinase [EC:2.7.1.48]","XP_017354538.1//PREDICTED: uridine-cytidine kinase 1 isoform X2 [Cebus capucinus imitator];NP_001305448.1//uridine-cytidine kinase 1 isoform e [Homo sapiens];NP_001248379.1//uridine-cytidine kinase 1 isoform c [Homo sapiens];NP_001248380.1//uridine-cytidine kinase 1 isoform d [Homo sapiens];XP_017354537.1//PREDICTED: uridine-cytidine kinase 1 isoform X1 [Cebus capucinus imitator]","1//3;3//A2MP1;2//1"]
[2013,5220,15.31,17.45,0.188752753597227,0.00592362449770642,"*",0.001940178,"EMP2","GO:0005634//nucleus;GO:0016324//apical plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0005737//cytoplasm;GO:0000139//Golgi membrane;GO:0009986//cell surface;GO:0045121//membrane raft;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0045177//apical part of cell;GO:0005886//plasma membrane","GO:0005178//integrin binding;GO:0019900//kinase binding;GO:0019901//protein kinase binding","GO:0045022//early endosome to late endosome transport;GO:0001954//positive regulation of cell-matrix adhesion;GO:0016477//cell migration;GO:0070252//actin-mediated cell contraction;GO:0003093//regulation of glomerular filtration;GO:0043534//blood vessel endothelial cell migration;GO:0007566//embryo implantation;GO:0007015//actin filament organization;GO:0008283//cell proliferation;GO:0001765//membrane raft assembly;GO:0010594//regulation of endothelial cell migration;GO:2001046//positive regulation of integrin-mediated signaling pathway;GO:0001913//T cell mediated cytotoxicity;GO:0032060//bleb assembly;GO:0072659//protein localization to plasma membrane;GO:0032147//activation of protein kinase activity;GO:0008219//cell death;GO:0007160//cell-matrix adhesion;GO:0007155//cell adhesion;GO:0045765//regulation of angiogenesis;GO:2001212//regulation of vasculogenesis;GO:0043549//regulation of kinase activity;GO:0034394//protein localization to cell surface;GO:0008284//positive regulation of cell proliferation","K19289//peripheral myelin protein 22","NP_001415.1//epithelial membrane protein 2 precursor [Homo sapiens]",5]
[2621,2551,3.16,3.6,0.188072348152572,0.487246301804265,"*",0.334734,"GAS6","GO:0070062//extracellular exosome;GO:0005788//endoplasmic reticulum lumen;GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process;GO:0005245//voltage-gated calcium channel activity;GO:0048018//receptor ligand activity;GO:0030971//receptor tyrosine kinase binding;GO:0030296//protein tyrosine kinase activator activity;GO:0060090//molecular adaptor activity;GO:0005509//calcium ion binding;GO:0001786//phosphatidylserine binding","GO:0031100//animal organ regeneration;GO:0019079//viral genome replication;GO:0010804//negative regulation of tumor necrosis factor-mediated signaling pathway;GO:0009267//cellular response to starvation;GO:0035690//cellular response to drug;GO:0007596//blood coagulation;GO:0043433//negative regulation of DNA binding transcription factor activity;GO:0043491//protein kinase B signaling;GO:0032825//positive regulation of natural killer cell differentiation;GO:0050711//negative regulation of interleukin-1 secretion;GO:0071363//cellular response to growth factor stimulus;GO:0035457//cellular response to interferon-alpha;GO:0045892//negative regulation of transcription, DNA-templated;GO:0033159//negative regulation of protein import into nucleus, translocation;GO:2000510//positive regulation of dendritic cell chemotaxis;GO:0010934//macrophage cytokine production;GO:0048146//positive regulation of fibroblast proliferation;GO:1900165//negative regulation of interleukin-6 secretion;GO:0010628//positive regulation of gene expression;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:0043277//apoptotic cell clearance;GO:0018105//peptidyl-serine phosphorylation;GO:0001764//neuron migration;GO:0035754//B cell chemotaxis;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0032148//activation of protein kinase B activity;GO:0051897//positive regulation of protein kinase B signaling;GO:0032720//negative regulation of tumor necrosis factor production;GO:0097241//hematopoietic stem cell migration to bone marrow;GO:0050766//positive regulation of phagocytosis;GO:0001961//positive regulation of cytokine-mediated signaling pathway;GO:0070168//negative regulation of biomineral tissue development;GO:0071307//cellular response to vitamin K;GO:0046827//positive regulation of protein export from nucleus;GO:2000270//negative regulation of fibroblast apoptotic process;GO:0072659//protein localization to plasma membrane;GO:0031589//cell-substrate adhesion;GO:1900142//negative regulation of oligodendrocyte apoptotic process;GO:0019064//fusion of virus membrane with host plasma membrane;GO:2000669//negative regulation of dendritic cell apoptotic process;GO:0097028//dendritic cell differentiation;GO:0046813//receptor-mediated virion attachment to host cell;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0032689//negative regulation of interferon-gamma production","K05464//growth arrest-specific 6","NP_000811.1//growth arrest-specific protein 6 precursor [Homo sapiens]","3//A2MP1"]
[79042,2270,52.03,59.26,0.18771491898459,0.000875820347432708,"*",2.42394E-4,"TSEN34","GO:0000214//tRNA-intron endonuclease complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus","GO:0016829//lyase activity;GO:0000213//tRNA-intron endonuclease activity","GO:0006397//mRNA processing;GO:0006388//tRNA splicing, via endonucleolytic cleavage and ligation;GO:0000379//tRNA-type intron splice site recognition and cleavage","K15323//tRNA-splicing endonuclease subunit Sen34 [EC:3.1.27.9]","NP_001269262.1//tRNA-splicing endonuclease subunit Sen34 isoform 2 [Homo sapiens];BAB15284.1//unnamed protein product [Homo sapiens]","1//3;4;3//A2MP1"]
[91120,3164,0.36,0.41,0.187627003175771,0.804076696801406,"*",0.716038,"ZNF682","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_012364882.1//PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 726 [Nomascus leucogenys]","1//3;2//1"]
[280636,1447,19.68,22.4,0.186768511605727,0.139721284577739,"*",0.0697032,"SELENOH","NA","NA","NA","K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K02927//large subunit ribosomal protein L40e;K15696//RING finger protein 113B;K17985//activating molecule in BECN1-regulated autophagy protein 1;K01064//wingless-type MMTV integration site family, member 9","XP_018891860.1//PREDICTED: selenoprotein H [Gorilla gorilla gorilla]","1//3;3//A2MP1"]
[1102,2892,0.29,0.33,0.186413124230881,0.890199570717266,"*",0.82823,"RCBTB2","GO:0001669//acrosomal vesicle","GO:0005087//Ran guanyl-nucleotide exchange factor activity","NA","K11494//RCC1 and BTB domain-containing protein","NP_001273761.1//RCC1 and BTB domain-containing protein 2 isoform 4 [Homo sapiens];NP_001339358.1//RCC1 and BTB domain-containing protein 2 isoform 5 precursor [Homo sapiens];NP_001259.1//RCC1 and BTB domain-containing protein 2 isoform 2 [Homo sapiens];BAG60659.1//unnamed protein product [Homo sapiens];NP_001339359.1//RCC1 and BTB domain-containing protein 2 isoform 6 [Homo sapiens];BAD92780.1//RCC1-like G exchanging factor RLG variant, partial [Homo sapiens];NP_001339360.1//RCC1 and BTB domain-containing protein 2 isoform 7 [Homo sapiens];NP_001273759.1//RCC1 and BTB domain-containing protein 2 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[4817,1760,24.19,27.52,0.186069700722173,0.26571824171123,"*",0.1524212,"NIT1","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005739//mitochondrion","GO:0016810//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds;GO:0000257//nitrilase activity","GO:0006807//nitrogen compound metabolic process","K13566//omega-amidase [EC:3.5.1.3];K20649//Rho GTPase-activating protein 39","NP_001172021.1//nitrilase homolog 1 isoform 2 [Homo sapiens];XP_005245272.1//PREDICTED: nitrilase homolog 1 isoform X1 [Homo sapiens];NP_001172022.1//nitrilase homolog 1 isoform 3 [Homo sapiens];XP_005245271.1//PREDICTED: nitrilase homolog 1 isoform X2 [Homo sapiens]","1//3;2//1"]
[1059,2856,102.65,116.72,0.185318160921926,{"v":5.28609454202247e-08,"d":"5.29E-08"},"*",{"v":7.36294e-09,"d":"7.36E-09"},"CENPB","GO:0016604//nuclear body;GO:0000780//condensed nuclear chromosome, centromeric region;GO:0031618//nuclear pericentric heterochromatin","GO:0003696//satellite DNA binding;GO:0003682//chromatin binding","NA","K11496//centromere protein B;K19607//X-linked retinitis pigmentosa GTPase regulator","XP_020732714.1//major centromere autoantigen B [Odocoileus virginianus texanus]",5]
[100507436,1613,20.4,23.19,0.184933667787146,0.15435325905019,"*",0.078742,"MICA","GO:0016021//integral component of membrane","NA","NA","K07985//MHC class I-related protein","NP_001170990.1//MHC class I polypeptide-related sequence A isoform 2 (MICA*00801) precursor [Homo sapiens];NP_001276083.1//MHC class I polypeptide-related sequence A isoform 4 (MICA*00801) [Homo sapiens];ARR96089.1//MHC class I chain-related protein A [Homo sapiens]","1//3;2//1"]
[4157,3115,9.89,11.24,0.184599609461815,0.126446842709943,"*",0.0614582,"MC1R","NA","NA","NA","K04199//melanocortin 1 receptor","Q864K8.1//RecName: Full=Melanocyte-stimulating hormone receptor; Short=MSH-R; AltName: Full=Melanocortin receptor 1; Short=MC1-R","3//A2MP1"]
[6419,1403,10.46,11.88,0.183651984553824,0.216157029197417,"*",0.1173478,"SETMAR","GO:0035861//site of double-strand break;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005694//chromosome","GO:0044547//DNA topoisomerase binding;GO:0003677//DNA binding;GO:0042800//histone methyltransferase activity (H3-K4 specific);GO:0000014//single-stranded DNA endodeoxyribonuclease activity;GO:0042803//protein homodimerization activity;GO:0003690//double-stranded DNA binding;GO:0003676//nucleic acid binding;GO:0003697//single-stranded DNA binding;GO:0046975//histone methyltransferase activity (H3-K36 specific);GO:0008270//zinc ion binding;GO:0004519//endonuclease activity;GO:0018024//histone-lysine N-methyltransferase activity","GO:0015074//DNA integration;GO:0010452//histone H3-K36 methylation;GO:2001251//negative regulation of chromosome organization;GO:0044774//mitotic DNA integrity checkpoint;GO:0051568//histone H3-K4 methylation;GO:2001034//positive regulation of double-strand break repair via nonhomologous end joining;GO:0000729//DNA double-strand break processing;GO:0008283//cell proliferation;GO:0031297//replication fork processing;GO:2000373//positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0071157//negative regulation of cell cycle arrest;GO:0000737//DNA catabolic process, endonucleolytic;GO:0097676//histone H3-K36 dimethylation;GO:0006303//double-strand break repair via nonhomologous end joining","K11433//histone-lysine N-methyltransferase SETMAR [EC:2.1.1.43]","AAH08931.2//SETMAR protein, partial [Homo sapiens];NP_006506.3//histone-lysine N-methyltransferase SETMAR isoform 1 [Homo sapiens];NP_001263254.1//histone-lysine N-methyltransferase SETMAR isoform 3 [Homo sapiens];NP_001307606.1//histone-lysine N-methyltransferase SETMAR isoform 6 [Homo sapiens];NP_001307607.1//histone-lysine N-methyltransferase SETMAR isoform 7 [Homo sapiens];NP_001230652.1//histone-lysine N-methyltransferase SETMAR isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[9277,2363,19.7,22.37,0.18336962671538,0.0536139065573771,"*",0.0229304,"WDR46","GO:0005654//nucleoplasm;GO:0030686//90S preribosome;GO:0032040//small-subunit processome;GO:0005730//nucleolus","GO:0003723//RNA binding","GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:1903955//positive regulation of protein targeting to mitochondrion;GO:0006364//rRNA processing","K14768//U3 small nucleolar RNA-associated protein 7","NP_001157739.1//WD repeat-containing protein 46 isoform 2 [Homo sapiens];NP_005443.3//WD repeat-containing protein 46 isoform 1 [Homo sapiens]","1//3;5"]
[55210,2495,20.14,22.86,0.182761720207694,0.113284884563934,"*",0.0540752,"ATAD3A","GO:0042645//mitochondrial nucleoid;GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion","GO:0005524//ATP binding","GO:0043066//negative regulation of apoptotic process;GO:0016049//cell growth","K17681//ATPase family AAA domain-containing protein 3A/B","XP_011540546.1//PREDICTED: ATPase family AAA domain-containing protein 3B isoform X4 [Homo sapiens];NP_114127.3//ATPase family AAA domain-containing protein 3B isoform AAA-TOB3l [Homo sapiens]","4;2//1"]
[311,2491,136.99,155.45,0.182380033544018,{"v":1.64331475585284E-8,"d":"1.64E-08"},"*",{"v":2.15316E-9,"d":"2.15E-09"},"ANXA11","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005654//nucleoplasm;GO:0005635//nuclear envelope;GO:0042581//specific granule;GO:0042470//melanosome;GO:0005737//cytoplasm;GO:0030496//midbody;GO:0045335//phagocytic vesicle;GO:0005829//cytosol;GO:0005819//spindle;GO:0042582//azurophil granule","GO:0003723//RNA binding;GO:0005544//calcium-dependent phospholipid binding;GO:0044548//S100 protein binding;GO:0008429//phosphatidylethanolamine binding;GO:0005509//calcium ion binding;GO:0048306//calcium-dependent protein binding;GO:0023026//MHC class II protein complex binding","GO:0051592//response to calcium ion;GO:0032506//cytokinetic process;GO:0006909//phagocytosis","K17095//annexin A7/11","NP_001148.1//annexin A11 isoform 1 [Homo sapiens];BAD93007.1//annexin A11 variant, partial [Homo sapiens]","1//3;2//1"]
[147184,2067,8.42,9.55,0.181680499856715,0.29374793605661,"*",0.1715154,"TMEM99","GO:0016021//integral component of membrane","NA","NA","K07604//type I keratin, acidic","NP_660317.2//transmembrane protein 99 precursor [Homo sapiens]","1//3;3//A2MP1"]
[5437,1322,22.31,25.29,0.180876523419098,0.228460205538046,"*",0.127059,"POLR2H","GO:0005665//DNA-directed RNA polymerase II, core complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0032993//protein-DNA complex;GO:0005666//DNA-directed RNA polymerase III complex;GO:0005736//DNA-directed RNA polymerase I complex","GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0003697//single-stranded DNA binding","GO:0032481//positive regulation of type I interferon production;GO:0045815//positive regulation of gene expression, epigenetic;GO:0006361//transcription initiation from RNA polymerase I promoter;GO:0042795//snRNA transcription from RNA polymerase II promoter;GO:0006370//7-methylguanosine mRNA capping;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0035019//somatic stem cell population maintenance;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0006362//transcription elongation from RNA polymerase I promoter;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0016070//RNA metabolic process;GO:0006363//termination of RNA polymerase I transcription;GO:0000398//mRNA splicing, via spliceosome;GO:0060964//regulation of gene silencing by miRNA;GO:0050434//positive regulation of viral transcription;GO:0006351//transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006383//transcription from RNA polymerase III promoter","K03016//DNA-directed RNA polymerases I, II, and III subunit RPABC3","XP_016797908.1//PREDICTED: DNA-directed RNA polymerases I, II, and III subunit RPABC3 isoform X1 [Pan troglodytes];XP_526411.3//PREDICTED: DNA-directed RNA polymerases I, II, and III subunit RPABC3 isoform X2 [Pan troglodytes];NP_001265627.1//DNA-directed RNA polymerases I, II, and III subunit RPABC3 isoform 1 [Homo sapiens];KFO04228.1//DNA-directed RNA polymerases I, II, and III subunit RPABC3, partial [Balearica regulorum gibbericeps]","1//3;4;2//1"]
[6636,806,99.94,113.27,0.180631685171711,0.0111475577706324,"*",0.0039066,"SNRPF","NA","NA","NA","K11098//small nuclear ribonucleoprotein F","ELK10363.1//Small nuclear ribonucleoprotein F [Pteropus alecto]","2//1"]
[84962,4042,21.34,24.18,0.180254068424699,0.015006166779661,"*",0.00543168,"AJUBA","GO:0005634//nucleus;GO:0005815//microtubule organizing center;GO:0005925//focal adhesion;GO:0000932//P-body;GO:0030027//lamellipodium;GO:0005912//adherens junction;GO:0005667//transcription factor complex;GO:0005911//cell-cell junction;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane","GO:0051015//actin filament binding;GO:0046872//metal ion binding;GO:0003714//transcription corepressor activity;GO:0003682//chromatin binding;GO:0045294//alpha-catenin binding","GO:0030032//lamellipodium assembly;GO:0006355//regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0030334//regulation of cell migration;GO:0048041//focal adhesion assembly;GO:1900037//regulation of cellular response to hypoxia;GO:0043406//positive regulation of MAP kinase activity;GO:0006351//transcription, DNA-templated;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0035331//negative regulation of hippo signaling;GO:0033673//negative regulation of kinase activity;GO:0001666//response to hypoxia;GO:0046474//glycerophospholipid biosynthetic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043087//regulation of GTPase activity;GO:0031334//positive regulation of protein complex assembly;GO:0035313//wound healing, spreading of epidermal cells;GO:0007010//cytoskeleton organization;GO:0034613//cellular protein localization;GO:0031328//positive regulation of cellular biosynthetic process;GO:0035195//gene silencing by miRNA;GO:0000086//G2/M transition of mitotic cell cycle;GO:2000637//positive regulation of gene silencing by miRNA","K16682//LIM domain-containing protein","XP_020018451.1//LIM domain-containing protein ajuba-like, partial [Castor canadensis];NP_001276026.1//LIM domain-containing protein ajuba isoform 3 [Homo sapiens];NP_116265.1//LIM domain-containing protein ajuba isoform 1 [Homo sapiens]","1//3;2//1;5"]
[3705,3282,45.88,51.96,0.179536039432056,0.00031550133102253,"*",{"v":7.9774e-05,"d":"7.98E-05"},"ITPK1","GO:0016324//apical plasma membrane;GO:0005829//cytosol;GO:0005622//intracellular","GO:0000287//magnesium ion binding;GO:0052825//inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity;GO:0052830//inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity;GO:0052725//inositol-1,3,4-trisphosphate 6-kinase activity;GO:0005524//ATP binding;GO:0016853//isomerase activity;GO:0047325//inositol tetrakisphosphate 1-kinase activity;GO:0003824//catalytic activity;GO:0052831//inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity;GO:0052659//inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity;GO:0052835//inositol-3,4,6-trisphosphate 1-kinase activity;GO:0052726//inositol-1,3,4-trisphosphate 5-kinase activity","GO:0007165//signal transduction;GO:0043647//inositol phosphate metabolic process;GO:0007596//blood coagulation;GO:0021915//neural tube development;GO:0032957//inositol trisphosphate metabolic process","K00913//inositol-1,3,4-trisphosphate 5/6-kinase / inositol-tetrakisphosphate 1-kinase [EC:2.7.1.159 2.7.1.134]","XP_008956466.1//PREDICTED: inositol-tetrakisphosphate 1-kinase isoform X2 [Pan paniscus];NP_055031.2//inositol-tetrakisphosphate 1-kinase isoform a [Homo sapiens]","2//1;5"]
[84418,926,104.04,117.77,0.178833778380039,0.00524304029835749,"*",0.001698556,"CYSTM1","NA","NA","NA","NA","XP_008984227.2//PREDICTED: cysteine-rich and transmembrane domain-containing protein 1 isoform X1 [Callithrix jacchus]","3//A2MP1"]
[4715,735,128.48,145.36,0.178086526716802,0.00652519009271523,"*",0.00215886,"NDUFB9","GO:0070062//extracellular exosome;GO:0005747//mitochondrial respiratory chain complex I;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0008137//NADH dehydrogenase (ubiquinone) activity","GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0007605//sensory perception of sound","K03965//NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 9","XP_004090853.2//PREDICTED: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 isoform X1 [Nomascus leucogenys]","1//3;2//1"]
[9212,1262,119.34,134.93,0.177133467165769,0.0201738763072821,"*",0.00757878,"AURKB","GO:0010369//chromocenter;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0051233//spindle midzone;GO:1990023//mitotic spindle midzone;GO:0000780//condensed nuclear chromosome, centromeric region;GO:0000779//condensed chromosome, centromeric region;GO:0032133//chromosome passenger complex;GO:0030496//midbody;GO:0005829//cytosol;GO:0005819//spindle;GO:0031616//spindle pole centrosome;GO:0005876//spindle microtubule","GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0046872//metal ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0019900//kinase binding;GO:0035174//histone serine kinase activity","GO:0051983//regulation of chromosome segregation;GO:0016925//protein sumoylation;GO:0051973//positive regulation of telomerase activity;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0051256//mitotic spindle midzone assembly;GO:0016570//histone modification;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0034644//cellular response to UV;GO:0007051//spindle organization;GO:0034501//protein localization to kinetochore;GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0002903//negative regulation of B cell apoptotic process;GO:0008283//cell proliferation;GO:0032091//negative regulation of protein binding;GO:0043988//histone H3-S28 phosphorylation;GO:0032467//positive regulation of cytokinesis;GO:1904355//positive regulation of telomere capping;GO:0036089//cleavage furrow formation;GO:0044878//mitotic cytokinesis checkpoint;GO:0031577//spindle checkpoint;GO:0009838//abscission;GO:0006468//protein phosphorylation;GO:0046777//protein autophosphorylation;GO:0007568//aging;GO:0008608//attachment of spindle microtubules to kinetochore;GO:1901796//regulation of signal transduction by p53 class mediator;GO:0007062//sister chromatid cohesion;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0032466//negative regulation of cytokinesis","K11479//aurora kinase B [EC:2.7.11.1]","EAW90079.1//aurora kinase B, isoform CRA_e [Homo sapiens];XP_020031087.1//aurora kinase B isoform X4 [Castor canadensis];AAH13300.2//AURKB protein, partial [Homo sapiens];XP_016802256.1//PREDICTED: aurora kinase B isoform X1 [Pan troglodytes];NP_001300882.1//aurora kinase B isoform 5 [Homo sapiens];NP_004208.2//aurora kinase B isoform 1 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[79759,2700,11.95,13.51,0.177017056457574,0.285344631533477,"*",0.165412,"ZNF668","GO:0005634//nucleus","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0003700//DNA binding transcription factor activity;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","XP_003124524.1//zinc finger protein 668 [Sus scrofa]","4;1//3"]
[64425,1884,22.87,25.85,0.176707914790624,0.0783281578742348,"*",0.0352462,"POLR1E","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0001650//fibrillar center;GO:0005736//DNA-directed RNA polymerase I complex","GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0003677//DNA binding;GO:0001179//RNA polymerase I transcription factor binding","GO:0006363//termination of RNA polymerase I transcription;GO:0006362//transcription elongation from RNA polymerase I promoter;GO:0001189//RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript;GO:0045815//positive regulation of gene expression, epigenetic;GO:0006361//transcription initiation from RNA polymerase I promoter;GO:0006351//transcription, DNA-templated;GO:0009303//rRNA transcription","K03005//DNA-directed RNA polymerase I subunit RPA49","NP_001269695.1//DNA-directed RNA polymerase I subunit RPA49 isoform 2 [Homo sapiens];NP_071935.1//DNA-directed RNA polymerase I subunit RPA49 isoform 1 [Homo sapiens]","1//3;2//1"]
[284338,1532,16.74,18.9,0.175086706558091,0.203583944940407,"*",0.1090692,"PRR19","NA","NA","NA","K16795//platelet-activating factor acetylhydrolase IB subunit beta/gamma [EC:3.1.1.47]","XP_005258836.2//PREDICTED: proline-rich protein 19 isoform X1 [Homo sapiens]","2//1"]
[11156,2764,3.18,3.59,0.174957078538696,0.579967060135541,"*",0.42323,"PTP4A3","GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0005769//early endosome;GO:0005737//cytoplasm","GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0004727//prenylated protein tyrosine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0016791//phosphatase activity","GO:0043542//endothelial cell migration;GO:0006355//regulation of transcription, DNA-templated;GO:1904951//positive regulation of establishment of protein localization;GO:1990830//cellular response to leukemia inhibitory factor;GO:0007219//Notch signaling pathway;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:1900746//regulation of vascular endothelial growth factor signaling pathway;GO:0043117//positive regulation of vascular permeability","K18041//protein tyrosine phosphatase type IVA [EC:3.1.3.48]","NP_009010.2//protein tyrosine phosphatase type IVA 3 isoform 2 [Homo sapiens];NP_116000.1//protein tyrosine phosphatase type IVA 3 isoform 1 [Homo sapiens]","3//A2MP1;2//1"]
[55869,2169,7.49,8.45,0.173985622710796,0.382156464081755,"*",0.238782,"HDAC8","GO:0005634//nucleus;GO:0005886//plasma membrane","GO:0004407//histone deacetylase activity;GO:0051879//Hsp90 protein binding;GO:0046872//metal ion binding;GO:0032041//NAD-dependent histone deacetylase activity (H3-K14 specific);GO:0030544//Hsp70 protein binding","GO:0031397//negative regulation of protein ubiquitination;GO:0071922//regulation of cohesin loading;GO:0007062//sister chromatid cohesion;GO:0031647//regulation of protein stability;GO:0006355//regulation of transcription, DNA-templated;GO:0032204//regulation of telomere maintenance;GO:0006351//transcription, DNA-templated","K11405//histone deacetylase 8 [EC:3.5.1.98]","XP_003317568.1//PREDICTED: histone deacetylase 8 isoform X12 [Pan troglodytes];EAW71821.1//histone deacetylase 8, isoform CRA_a [Homo sapiens];XP_011853603.1//PREDICTED: histone deacetylase 8 isoform X4 [Mandrillus leucophaeus];XP_016798636.1//PREDICTED: histone deacetylase 8 isoform X10 [Pan troglodytes];XP_009196076.1//histone deacetylase 8 isoform X3 [Papio anubis];EAW71824.1//histone deacetylase 8, isoform CRA_d [Homo sapiens]","1//3;2//1"]
[10312,2607,66.92,75.46,0.173274654771757,0.000468652408321377,"*",1.226934E-4,"TCIRG1","GO:0005765//lysosomal membrane;GO:0010008//endosome membrane;GO:0000220//vacuolar proton-transporting V-type ATPase, V0 domain;GO:0016324//apical plasma membrane;GO:0101003//ficolin-1-rich granule membrane;GO:0030670//phagocytic vesicle membrane;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0016471//vacuolar proton-transporting V-type ATPase complex","GO:0015078//hydrogen ion transmembrane transporter activity;GO:0051117//ATPase binding;GO:0005215//transporter activity;GO:0046961//proton-transporting ATPase activity, rotational mechanism","GO:0008286//insulin receptor signaling pathway;GO:0034220//ion transmembrane transport;GO:0070072//vacuolar proton-transporting V-type ATPase complex assembly;GO:0090383//phagosome acidification;GO:0007035//vacuolar acidification;GO:0006968//cellular defense response;GO:0015986//ATP synthesis coupled proton transport;GO:0015991//ATP hydrolysis coupled proton transport;GO:0007039//protein catabolic process in the vacuole;GO:0033572//transferrin transport;GO:0043312//neutrophil degranulation;GO:0015992//proton transport;GO:0016236//macroautophagy;GO:0008284//positive regulation of cell proliferation","K02154//V-type H+-transporting ATPase subunit a","NP_006010.2//V-type proton ATPase 116 kDa subunit a isoform 3 isoform a [Homo sapiens];NP_006044.1//V-type proton ATPase 116 kDa subunit a isoform 3 isoform b [Homo sapiens]","1//3;3//A2MP1"]
[23180,3033,1.02,1.15,0.17306470897288,0.696060444210526,"*",0.579542,"RFTN1","GO:0070062//extracellular exosome;GO:0005768//endosome;GO:0045121//membrane raft;GO:0043234//protein complex;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0003725//double-stranded RNA binding","GO:0050853//B cell receptor signaling pathway;GO:0050852//T cell receptor signaling pathway;GO:0002457//T cell antigen processing and presentation;GO:0032620//interleukin-17 production;GO:0043330//response to exogenous dsRNA;GO:0033227//dsRNA transport;GO:0032596//protein transport into membrane raft;GO:1903044//protein localization to membrane raft;GO:0001765//membrane raft assembly;GO:0040007//growth;GO:0034138//toll-like receptor 3 signaling pathway","K08379//prokineticin receptor 1","AAH51336.1//Raftlin, lipid raft linker 1, partial [Homo sapiens]","1//3"]
[146429,1860,1.34,1.51,0.172315548867307,0.732659632650041,"*",0.619784,"SLC22A31","NA","NA","NA","K08213//MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 17","A6NKX4.3//RecName: Full=Putative solute carrier family 22 member 31","1//3"]
[5025,2054,9.61,10.82,0.171092163053065,0.308159994366197,"*",0.1821682,"P2RX4","GO:0016020//membrane;GO:0005765//lysosomal membrane;GO:0070062//extracellular exosome;GO:0098794//postsynapse;GO:0030054//cell junction;GO:0005639//integral component of nuclear inner membrane;GO:0043195//terminal bouton;GO:0014069//postsynaptic density;GO:0048471//perinuclear region of cytoplasm;GO:0043025//neuronal cell body;GO:0005887//integral component of plasma membrane;GO:0043197//dendritic spine;GO:0005886//plasma membrane","GO:0004931//extracellularly ATP-gated cation channel activity;GO:0005524//ATP binding;GO:0005102//receptor binding;GO:0042803//protein homodimerization activity;GO:0045296//cadherin binding;GO:0005507//copper ion binding;GO:0008144//drug binding;GO:0008270//zinc ion binding;GO:0001614//purinergic nucleotide receptor activity","GO:0033198//response to ATP;GO:0008217//regulation of blood pressure;GO:2001028//positive regulation of endothelial cell chemotaxis;GO:0050850//positive regulation of calcium-mediated signaling;GO:0002028//regulation of sodium ion transport;GO:0007596//blood coagulation;GO:0034220//ion transmembrane transport;GO:0097190//apoptotic signaling pathway;GO:0051260//protein homooligomerization;GO:0032308//positive regulation of prostaglandin secretion;GO:0019228//neuronal action potential;GO:0071318//cellular response to ATP;GO:0019233//sensory perception of pain;GO:0055119//relaxation of cardiac muscle;GO:0035590//purinergic nucleotide receptor signaling pathway;GO:0006810//transport;GO:0007165//signal transduction;GO:0055117//regulation of cardiac muscle contraction;GO:0001894//tissue homeostasis;GO:0010614//negative regulation of cardiac muscle hypertrophy;GO:0034405//response to fluid shear stress;GO:0051899//membrane depolarization;GO:0042118//endothelial cell activation;GO:0010524//positive regulation of calcium ion transport into cytosol;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0051928//positive regulation of calcium ion transport","K05218//P2X purinoceptor 4","XP_017399747.1//PREDICTED: P2X purinoceptor 4 [Cebus capucinus imitator]","1//3;2//1"]
[7419,1554,92,103.58,0.171039697299111,0.000795214233280073,"*",2.18094E-4,"VDAC3","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005743//mitochondrial inner membrane;GO:0046930//pore complex;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane","GO:0015288//porin activity;GO:0008308//voltage-gated anion channel activity;GO:0000166//nucleotide binding","GO:1902017//regulation of cilium assembly;GO:0015853//adenine transport;GO:0007612//learning;GO:0007270//neuron-neuron synaptic transmission;GO:0001662//behavioral fear response","K15041//voltage-dependent anion channel protein 3","NP_005653.3//voltage-dependent anion-selective channel protein 3 isoform 1 [Homo sapiens];NP_001129166.1//voltage-dependent anion-selective channel protein 3 isoform 2 [Homo sapiens]","6;2//1"]
[112970,1712,7.91,8.9,0.170127641380968,0.400244049879169,"*",0.259204,"KTI12","NA","GO:0005524//ATP binding","NA","K15456//protein KTI12","XP_004089847.1//PREDICTED: protein KTI12 homolog isoform X1 [Nomascus leucogenys]","2//1"]
[84074,5411,0.48,0.54,0.169925001442313,0.732843485751767,"*",0.629482,"QRICH2","NA","NA","NA","K19926//zona pellucida sperm-binding protein 1","XP_016880695.1//PREDICTED: glutamine-rich protein 2 isoform X2 [Homo sapiens]","2//1"]
[4858,7673,0.16,0.18,0.169925001442312,0.814267720995053,"*",0.731536,"NOVA2","GO:0005634//nucleus","GO:0003723//RNA binding","GO:0000398//mRNA splicing, via spliceosome;GO:0051252//regulation of RNA metabolic process","K14944//RNA-binding protein Nova","EAW57397.1//neuro-oncological ventral antigen 2 [Homo sapiens]","3//A2MP1"]
[112770,1602,57.32,64.46,0.169365578797399,0.0196252152591107,"*",0.00734932,"GLMP","GO:0005765//lysosomal membrane;GO:0005634//nucleus;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005764//lysosome","GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0044212//transcription regulatory region DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0004879//nuclear receptor activity","GO:0045944//positive regulation of transcription from RNA polymerase II promoter","NA","AAH11575.1//C1orf85 protein, partial [Homo sapiens];XP_007974957.1//PREDICTED: lysosomal protein NCU-G1 isoform X4 [Chlorocebus sabaeus];NP_001243534.1//glycosylated lysosomal membrane protein isoform 3 [Homo sapiens];NP_001243533.1//glycosylated lysosomal membrane protein isoform 2 precursor [Homo sapiens];NP_653181.1//glycosylated lysosomal membrane protein isoform 1 precursor [Homo sapiens]","1//3;2//1"]
[100462977,1555,426.31,479.24,0.168845431243319,{"v":5.12063391708126e-14,"d":"5.12E-14"},"*",{"v":3.86596e-15,"d":"3.87E-15"},"MTRNR2L1","NA","NA","NA","K22237//Rab effector MyRIP","XP_012365851.1//PREDICTED: rab effector MyRIP [Nomascus leucogenys]","1//3"]
[11072,1508,29.85,33.54,0.168151757412179,0.0896707462605385,"*",0.041282,"DUSP14","NA","GO:0017017//MAP kinase tyrosine/serine/threonine phosphatase activity;GO:0003723//RNA binding;GO:0004725//protein tyrosine phosphatase activity","GO:0035335//peptidyl-tyrosine dephosphorylation","K14165//atypical dual specificity phosphatase [EC:3.1.3.16 3.1.3.48]","KFO32189.1//Dual specificity protein phosphatase 14 [Fukomys damarensis]","3//A2MP1"]
[51154,2273,38.67,43.42,0.167144961532337,0.0125707701003698,"*",0.0044691,"MRTO4","GO:0005730//nucleolus;GO:0005737//cytoplasm","GO:0003723//RNA binding","GO:0000027//ribosomal large subunit assembly;GO:0006364//rRNA processing;GO:0000956//nuclear-transcribed mRNA catabolic process","K14815//mRNA turnover protein 4","NP_057267.2//mRNA turnover protein 4 homolog [Homo sapiens]","3//A2MP1"]
[79034,2195,20.29,22.77,0.166365426379964,0.0952223697746593,"*",0.0441776,"C7orf26","NA","NA","NA","K04594//latrophilin 3","NP_001289968.1//uncharacterized protein C7orf26 isoform 2 [Homo sapiens];NP_076972.2//uncharacterized protein C7orf26 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[90410,1101,15.59,17.48,0.165084256802814,0.645775080634501,"*",0.489324,"IFT20","GO:0030992//intraciliary transport particle B;GO:0005929//cilium;GO:0005801//cis-Golgi network;GO:0000139//Golgi membrane;GO:0097542//ciliary tip;GO:0031514//motile cilium;GO:0032420//stereocilium;GO:1902636//kinociliary basal body;GO:0070062//extracellular exosome;GO:0032391//photoreceptor connecting cilium;GO:0005813//centrosome;GO:0005902//microvillus;GO:0001750//photoreceptor outer segment;GO:0005814//centriole;GO:0005794//Golgi apparatus;GO:0044292//dendrite terminus;GO:0097546//ciliary base","GO:0002046//opsin binding;GO:0017137//Rab GTPase binding","GO:0008542//visual learning;GO:0034067//protein localization to Golgi apparatus;GO:0001822//kidney development;GO:1902017//regulation of cilium assembly;GO:0061512//protein localization to cilium;GO:0060828//regulation of canonical Wnt signaling pathway;GO:0051642//centrosome localization;GO:0060271//cilium assembly;GO:0042073//intraciliary transport;GO:0035735//intraciliary transport involved in cilium assembly;GO:0007224//smoothened signaling pathway;GO:0055007//cardiac muscle cell differentiation;GO:0061351//neural precursor cell proliferation;GO:2000785//regulation of autophagosome assembly;GO:0035845//photoreceptor cell outer segment organization;GO:0072659//protein localization to plasma membrane;GO:0060122//inner ear receptor cell stereocilium organization;GO:0036372//opsin transport;GO:0001736//establishment of planar polarity;GO:0090102//cochlea development","K16473//intraflagellar transport protein 20","XP_021572576.1//intraflagellar transport protein 20 homolog isoform X2 [Carlito syrichta];XP_017744399.1//PREDICTED: intraflagellar transport protein 20 homolog isoform X2 [Rhinopithecus bieti];NP_001254703.1//intraflagellar transport protein 20 homolog isoform 1 [Homo sapiens];XP_021068636.1//intraflagellar transport protein 20 homolog isoform X1 [Mus pahari];NP_777547.1//intraflagellar transport protein 20 homolog isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[8525,3676,23.05,25.84,0.164839319377224,0.0106864194213836,"*",0.00372292,"DGKZ","GO:0005634//nucleus;GO:0005622//intracellular;GO:0016607//nuclear speck;GO:0005886//plasma membrane;GO:0030027//lamellipodium;GO:0005737//cytoplasm","GO:0004143//diacylglycerol kinase activity;GO:0003951//NAD+ kinase activity;GO:0046872//metal ion binding;GO:0008022//protein C-terminus binding;GO:0001727//lipid kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity","GO:0031571//mitotic G1 DNA damage checkpoint;GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0016477//cell migration;GO:0045930//negative regulation of mitotic cell cycle;GO:0046486//glycerolipid metabolic process;GO:0030168//platelet activation;GO:0035556//intracellular signal transduction;GO:0046339//diacylglycerol metabolic process;GO:0046834//lipid phosphorylation","K00901//diacylglycerol kinase (ATP) [EC:2.7.1.107]","XP_016776258.1//PREDICTED: diacylglycerol kinase zeta isoform X15 [Pan troglodytes];NP_001186195.1//diacylglycerol kinase zeta isoform 5 [Homo sapiens];NP_003637.2//diacylglycerol kinase zeta isoform 2 [Homo sapiens];XP_016873945.1//PREDICTED: diacylglycerol kinase zeta isoform X2 [Homo sapiens];NP_963290.1//diacylglycerol kinase zeta isoform 1 [Homo sapiens];NP_001186196.1//diacylglycerol kinase zeta isoform 6 [Homo sapiens];NP_001186197.1//diacylglycerol kinase zeta isoform 7 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[7263,1111,25.59,28.68,0.164464876662458,0.226147989092149,"*",0.124598,"TST","GO:0005759//mitochondrial matrix;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0004792//thiosulfate sulfurtransferase activity;GO:0008097//5S rRNA binding","GO:0009440//cyanate catabolic process;GO:0035928//rRNA import into mitochondrion;GO:0051029//rRNA transport;GO:0030855//epithelial cell differentiation","K01011//thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]","XP_012642573.1//thiosulfate sulfurtransferase isoform X1 [Microcebus murinus];NP_003303.2//thiosulfate sulfurtransferase [Homo sapiens]","1//3;5"]
[8663,3100,127.95,143.29,0.163357782154206,{"v":3.08997666449511e-08,"d":"3.09E-08"},"*",{"v":4.15698e-09,"d":"4.16E-09"},"EIF3C","GO:0071541//eukaryotic translation initiation factor 3 complex, eIF3m;GO:0016282//eukaryotic 43S preinitiation complex;GO:0005829//cytosol;GO:0033290//eukaryotic 48S preinitiation complex;GO:0005852//eukaryotic translation initiation factor 3 complex","GO:0003743//translation initiation factor activity;GO:0003723//RNA binding;GO:0031369//translation initiation factor binding","GO:0006413//translational initiation;GO:0006446//regulation of translational initiation;GO:0045727//positive regulation of translation;GO:1902416//positive regulation of mRNA binding;GO:0001731//formation of translation preinitiation complex","K03252//translation initiation factor 3 subunit C","NP_001273407.1//eukaryotic translation initiation factor 3 subunit C isoform b [Homo sapiens];NP_003743.1//eukaryotic translation initiation factor 3 subunit C isoform a [Homo sapiens]","4;1//3;2//1"]
[4718,2490,49.75,55.69,0.162721766978638,0.00330456823893805,"*",0.001028566,"NDUFC2","GO:0005737//cytoplasm;GO:0035577//azurophil granule membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0070469//respiratory chain;GO:0005886//plasma membrane","GO:0008137//NADH dehydrogenase (ubiquinone) activity","GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0043312//neutrophil degranulation","K03968//NADH dehydrogenase (ubiquinone) 1 subunit C2","NP_001190983.1//NADH dehydrogenase [ubiquinone] 1 subunit C2 isoform 2 [Homo sapiens];NP_004540.1//NADH dehydrogenase [ubiquinone] 1 subunit C2 isoform 1 [Homo sapiens];NP_001190984.1//NADH dehydrogenase [ubiquinone] 1 subunit C2 isoform 3 [Homo sapiens]","1//3;5"]
[388789,551,64.24,71.87,0.161917793204006,0.176049102775442,"*",0.0917276,"SMIM26","NA","NA","NA","K07560//D-tyrosyl-tRNA(Tyr) deacylase [EC:3.1.-.-]","EAX10230.1//hCG21678 [Homo sapiens]","1//3"]
[823,3104,75.08,83.94,0.160929813055035,{"v":5.04744693812375e-05,"d":"5.05E-05"},"*",{"v":1.108138e-05,"d":"1.11E-05"},"CAPN1","GO:0070062//extracellular exosome;GO:0005925//focal adhesion;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005739//mitochondrion;GO:0005764//lysosome;GO:0005886//plasma membrane","GO:0004198//calcium-dependent cysteine-type endopeptidase activity;GO:0005509//calcium ion binding","GO:0060056//mammary gland involution;GO:0032801//receptor catabolic process;GO:0097264//self proteolysis;GO:0050790//regulation of catalytic activity","K01367//calpain-1 [EC:3.4.22.52]","XP_012666158.1//PREDICTED: calpain-1 catalytic subunit [Otolemur garnettii]","1//3;3//A2MP1"]
[10461,3632,0.68,0.76,0.160464672193246,0.732822325388601,"*",0.619784,"MERTK","GO:0005615//extracellular space;GO:0016028//rhabdomere;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0001750//photoreceptor outer segment;GO:0005737//cytoplasm","GO:0005524//ATP binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity","GO:0060041//retina development in camera-type eye;GO:0060068//vagina development;GO:0051250//negative regulation of lymphocyte activation;GO:0043491//protein kinase B signaling;GO:0030168//platelet activation;GO:0007166//cell surface receptor signaling pathway;GO:0007283//spermatogenesis;GO:0050766//positive regulation of phagocytosis;GO:0001818//negative regulation of cytokine production;GO:0006909//phagocytosis;GO:0034446//substrate adhesion-dependent cell spreading;GO:0050900//leukocyte migration;GO:0007267//cell-cell signaling;GO:0001779//natural killer cell differentiation;GO:0006468//protein phosphorylation;GO:0043277//apoptotic cell clearance;GO:0032940//secretion by cell;GO:0097350//neutrophil clearance;GO:2000107//negative regulation of leukocyte apoptotic process","K05117//c-mer proto-oncogene tyrosine kinase [EC:2.7.10.1]","NP_006334.2//tyrosine-protein kinase Mer precursor [Homo sapiens]","2//1"]
[10591,712,47.56,53.12,0.159506431601269,0.14675283099814,"*",0.074093,"DNPH1","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0070694//deoxyribonucleoside 5'-monophosphate N-glycosidase activity;GO:0042802//identical protein binding;GO:0050144//nucleoside deoxyribosyltransferase activity;GO:0042803//protein homodimerization activity","GO:0009159//deoxyribonucleoside monophosphate catabolic process;GO:0009116//nucleoside metabolic process;GO:0008283//cell proliferation;GO:0006195//purine nucleotide catabolic process;GO:0030307//positive regulation of cell growth;GO:0009117//nucleotide metabolic process;GO:0030855//epithelial cell differentiation","NA","EAX04165.1//chromosome 6 open reading frame 108, isoform CRA_a [Homo sapiens];NP_006434.1//2'-deoxynucleoside 5'-phosphate N-hydrolase 1 isoform 1 [Homo sapiens]","1//3;2//1"]
[63908,3767,1.63,1.82,0.159066485967619,0.631245661948376,"*",0.4746,"NAPB","GO:0005774//vacuolar membrane;GO:0070062//extracellular exosome;GO:0005622//intracellular;GO:0043209//myelin sheath;GO:0031201//SNARE complex;GO:0045202//synapse;GO:0070044//synaptobrevin 2-SNAP-25-syntaxin-1a complex","GO:0005483//soluble NSF attachment protein activity;GO:0019905//syntaxin binding","GO:0006886//intracellular protein transport;GO:0048488//synaptic vesicle endocytosis;GO:0061025//membrane fusion;GO:0035249//synaptic transmission, glutamatergic;GO:0010807//regulation of synaptic vesicle priming;GO:0035494//SNARE complex disassembly","K15296//alpha-soluble NSF attachment protein;K05858//phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]","NP_062606.1//beta-soluble NSF attachment protein [Mus musculus];NP_001269949.1//beta-soluble NSF attachment protein isoform c [Homo sapiens];NP_001269947.1//beta-soluble NSF attachment protein isoform a [Homo sapiens];XP_012666003.1//PREDICTED: beta-soluble NSF attachment protein isoform X3 [Otolemur garnettii]","1//3;2//1"]
[6227,418,235.38,262.71,0.158479376146328,0.0181535911103611,"*",0.00673458,"RPS21","GO:0005840//ribosome;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0022627//cytosolic small ribosomal subunit;GO:0015935//small ribosomal subunit","GO:0043022//ribosome binding;GO:0003723//RNA binding;GO:0047485//protein N-terminus binding;GO:0003735//structural constituent of ribosome","GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0000461//endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000447//endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006364//rRNA processing;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006413//translational initiation;GO:0006412//translation;GO:0019083//viral transcription","K02971//small subunit ribosomal protein S21e","XP_011964398.1//PREDICTED: 40S ribosomal protein S21 isoform X3 [Ovis aries musimon]","3//A2MP1"]
[79701,4403,9.44,10.53,0.157646671663876,0.119090887795993,"*",0.0573014,"OGFOD3","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0016021//integral component of membrane","GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0005506//iron ion binding;GO:0031418//L-ascorbic acid binding;GO:0051213//dioxygenase activity","NA","K22069//LYR motif-containing protein 4;K12581//CCR4-NOT transcription complex subunit 7/8","NP_078924.1//2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3 isoform 1 [Homo sapiens];NP_787098.3//2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3 isoform 2 [Homo sapiens]","4;2//1"]
[51082,1181,60.05,66.97,0.157350722119159,0.148631859315119,"*",0.075265,"POLR1D","GO:0005666//DNA-directed RNA polymerase III complex;GO:0005736//DNA-directed RNA polymerase I complex","GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0003677//DNA binding;GO:0046983//protein dimerization activity","GO:0006360//transcription from RNA polymerase I promoter;GO:0006351//transcription, DNA-templated;GO:0006383//transcription from RNA polymerase III promoter","K03020//DNA-directed RNA polymerases I and III subunit RPAC2","NP_057056.1//DNA-directed RNA polymerases I and III subunit RPAC2 isoform 1 [Homo sapiens];XP_008969889.1//PREDICTED: uncharacterized protein LOC100990631 [Pan paniscus];NP_689918.1//DNA-directed RNA polymerases I and III subunit RPAC2 isoform 2 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[284361,2126,133.69,149.06,0.15700160876454,{"v":1.0563796244373e-05,"d":"1.06E-05"},"*",{"v":2.05668E-6,"d":"2.06E-06"},"EMC10","GO:0072546//ER membrane protein complex;GO:0016021//integral component of membrane;GO:0005576//extracellular region","NA","NA","K19475//WAS/WASL-interacting protein;K11448//lysine-specific demethylase 6B [EC:1.14.11.-]","NP_996261.1//ER membrane protein complex subunit 10 isoform 2 precursor [Homo sapiens]","3//A2MP1;5"]
[83877,3359,16.72,18.63,0.156052826860755,0.10638379088017,"*",0.0502416,"TM2D2","GO:0016021//integral component of membrane","NA","NA","K15696//RING finger protein 113B;K17985//activating molecule in BECN1-regulated autophagy protein 1;K09488//TNF receptor-associated protein 1","XP_002757017.2//PREDICTED: TM2 domain-containing protein 2 [Callithrix jacchus];NP_114146.3//TM2 domain-containing protein 2 isoform b [Homo sapiens]","1//3;3//A2MP1;2//1"]
[100287932,1239,99.95,111.33,0.155563934786692,0.005749268,"*",0.001877312,"TIMM23","GO:0005744//mitochondrial inner membrane presequence translocase complex;GO:0016021//integral component of membrane;GO:0005758//mitochondrial intermembrane space;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0031305//integral component of mitochondrial inner membrane","GO:0015266//protein channel activity;GO:0015450//P-P-bond-hydrolysis-driven protein transmembrane transporter activity","GO:0006886//intracellular protein transport;GO:0006626//protein targeting to mitochondrion;GO:0030150//protein import into mitochondrial matrix","K17794//mitochondrial import inner membrane translocase subunit TIM23","NP_006318.1//mitochondrial import inner membrane translocase subunit Tim23 [Homo sapiens]","3//A2MP1"]
[3030,3048,67.09,74.7,0.155010499324512,0.000222804521335712,"*",{"v":5.47178E-5,"d":"5.47E-05"},"HADHA","GO:0031012//extracellular matrix;GO:0042645//mitochondrial nucleoid;GO:0016507//mitochondrial fatty acid beta-oxidation multienzyme complex;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0051287//NAD binding;GO:0000062//fatty-acyl-CoA binding;GO:0003988//acetyl-CoA C-acyltransferase activity;GO:0016509//long-chain-3-hydroxyacyl-CoA dehydrogenase activity;GO:0003985//acetyl-CoA C-acetyltransferase activity;GO:0003857//3-hydroxyacyl-CoA dehydrogenase activity;GO:0016508//long-chain-enoyl-CoA hydratase activity;GO:0004300//enoyl-CoA hydratase activity;GO:0032403//protein complex binding","GO:0042493//response to drug;GO:0006635//fatty acid beta-oxidation;GO:0032868//response to insulin;GO:0035965//cardiolipin acyl-chain remodeling","K07515//enoyl-CoA hydratase / long-chain 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.211]","NP_000173.2//trifunctional enzyme subunit alpha, mitochondrial precursor [Homo sapiens]",4]
[10695,1787,27.49,30.6,0.154624746067061,0.0362845182965592,"*",0.01472142,"CNPY3","GO:0005788//endoplasmic reticulum lumen","GO:0005102//receptor binding","GO:0002224//toll-like receptor signaling pathway;GO:0045087//innate immune response","NA","NP_001305771.1//protein canopy homolog 3 isoform 3 precursor [Homo sapiens];NP_001305774.1//protein canopy homolog 3 isoform 2 [Homo sapiens];NP_001305776.1//protein canopy homolog 3 isoform 5 precursor [Homo sapiens];NP_001305777.1//protein canopy homolog 3 isoform 6 precursor [Homo sapiens];NP_006577.2//protein canopy homolog 3 isoform 1 precursor [Homo sapiens]","1//3;4"]
[27351,3804,21.71,24.16,0.154260728709935,0.0282851163351455,"*",0.01107394,"DESI1","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0008233//peptidase activity;GO:0042802//identical protein binding","NA","K11447//histone demethylase [EC:1.14.11.-];K17985//activating molecule in BECN1-regulated autophagy protein 1","XP_007974111.1//PREDICTED: desumoylating isopeptidase 1 [Chlorocebus sabaeus]","2//1"]
[374,1290,42.66,47.45,0.1535241215679,0.0883558204003813,"*",0.0406158,"AREG","GO:0005634//nucleus;GO:0005615//extracellular space;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0005737//cytoplasm;GO:0000139//Golgi membrane;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0012507//ER to Golgi transport vesicle membrane","GO:0008083//growth factor activity;GO:0005125//cytokine activity;GO:0005154//epidermal growth factor receptor binding","GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0048208//COPII vesicle coating;GO:0060598//dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis;GO:0032355//response to estradiol;GO:0008283//cell proliferation;GO:0045668//negative regulation of osteoblast differentiation;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0031175//neuron projection development;GO:0051384//response to glucocorticoid;GO:0007186//G-protein coupled receptor signaling pathway;GO:0043434//response to peptide hormone;GO:0051591//response to cAMP;GO:0007267//cell-cell signaling;GO:0060744//mammary gland branching involved in thelarche;GO:0042542//response to hydrogen peroxide;GO:0045740//positive regulation of DNA replication;GO:0060749//mammary gland alveolus development;GO:0060750//epithelial cell proliferation involved in mammary gland duct elongation;GO:0014009//glial cell proliferation;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0008284//positive regulation of cell proliferation","K09782//amphiregulin","NP_001648.1//amphiregulin preproprotein [Homo sapiens]","3//A2MP1"]
[355,3942,2.94,3.27,0.153474480661718,0.473777420564183,"*",0.322782,"FAS","GO:0016020//membrane;GO:0031264//death-inducing signaling complex;GO:0009986//cell surface;GO:0031265//CD95 death-inducing signaling complex;GO:0005829//cytosol","GO:0004872//receptor activity;GO:0042802//identical protein binding;GO:0004888//transmembrane signaling receptor activity;GO:0019900//kinase binding;GO:0005516//calmodulin binding","GO:0097296//activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway;GO:0006955//immune response;GO:0006924//activation-induced cell death of T cells;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006915//apoptotic process","K04390//tumor necrosis factor receptor superfamily member 6","NP_690611.1//tumor necrosis factor receptor superfamily member 6 isoform 3 precursor [Homo sapiens];NP_001307548.1//tumor necrosis factor receptor superfamily member 6 isoform 4 precursor [Homo sapiens];NP_690610.1//tumor necrosis factor receptor superfamily member 6 isoform 2 precursor [Homo sapiens];NP_000034.1//tumor necrosis factor receptor superfamily member 6 isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1;5"]
[9114,1688,62.74,69.75,0.152807687760309,0.0125802700035199,"*",0.00447484,"ATP6V0D1","GO:0016020//membrane;GO:0010008//endosome membrane;GO:0033179//proton-transporting V-type ATPase, V0 domain;GO:0005765//lysosomal membrane;GO:0070062//extracellular exosome;GO:0016324//apical plasma membrane;GO:0008021//synaptic vesicle;GO:0005813//centrosome;GO:0030670//phagocytic vesicle membrane;GO:0043005//neuron projection;GO:0043234//protein complex;GO:0005623//cell;GO:0043679//axon terminus;GO:0005769//early endosome;GO:0016471//vacuolar proton-transporting V-type ATPase complex","GO:0015078//hydrogen ion transmembrane transporter activity;GO:0008553//hydrogen-exporting ATPase activity, phosphorylative mechanism;GO:0032403//protein complex binding;GO:0046961//proton-transporting ATPase activity, rotational mechanism","GO:0016241//regulation of macroautophagy;GO:0006879//cellular iron ion homeostasis;GO:0008286//insulin receptor signaling pathway;GO:0034220//ion transmembrane transport;GO:0036295//cellular response to increased oxygen levels;GO:0090383//phagosome acidification;GO:0007420//brain development;GO:0007034//vacuolar transport;GO:0007035//vacuolar acidification;GO:0015991//ATP hydrolysis coupled proton transport;GO:0060271//cilium assembly;GO:0036498//IRE1-mediated unfolded protein response;GO:0033572//transferrin transport;GO:0015992//proton transport","K02146//V-type H+-transporting ATPase subunit d","NP_004682.2//V-type proton ATPase subunit d 1 [Homo sapiens]",4]
[6230,514,449.03,498.95,0.152083414074014,0.000225205332620321,"*",{"v":5.53638E-5,"d":"5.54E-05"},"RPS25","NA","NA","NA","K02975//small subunit ribosomal protein S25e","XP_012363578.1//PREDICTED: LOW QUALITY PROTEIN: 40S ribosomal protein S25-like [Nomascus leucogenys]","2//1"]
[25759,2509,0.54,0.6,0.15200309344505,0.819513260700389,"*",0.738352,"SHC2","GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0030971//receptor tyrosine kinase binding","GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0000165//MAPK cascade;GO:0000187//activation of MAPK activity;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0007265//Ras protein signal transduction","K17447//SHC-transforming protein 2","NP_036567.2//SHC-transforming protein 2 [Homo sapiens]","2//1"]
[5339,14712,51.23,56.9,0.151439760739381,{"v":9.46245887767796e-12,"d":"9.46E-12"},"*",{"v":8.57154e-13,"d":"8.57E-13"},"PLEC","GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0005925//focal adhesion;GO:0005903//brush border;GO:0045111//intermediate filament cytoskeleton;GO:0043034//costamere;GO:0016528//sarcoplasm;GO:0005829//cytosol;GO:0030056//hemidesmosome;GO:0042383//sarcolemma;GO:0005886//plasma membrane","GO:0003779//actin binding;GO:0003723//RNA binding;GO:0008307//structural constituent of muscle;GO:0030506//ankyrin binding;GO:0045296//cadherin binding","GO:0031581//hemidesmosome assembly","K10388//plectin","NP_958784.1//plectin isoform 1b [Homo sapiens];NP_958781.1//plectin isoform 1e [Homo sapiens];NP_958780.1//plectin isoform 1f [Homo sapiens];NP_958783.1//plectin isoform 1d [Homo sapiens];NP_958785.1//plectin isoform 1g [Homo sapiens];NP_000436.2//plectin isoform 1c [Homo sapiens];NP_958786.1//plectin isoform 1a [Homo sapiens];NP_958782.1//plectin isoform 1 [Homo sapiens]","4;3//A2MP1;2//1"]
[283951,994,15.75,17.48,0.150353356225957,0.432213649262202,"*",0.28605,"C16orf91","GO:0016021//integral component of membrane","NA","NA","NA","AAK61280.1//unknown [Homo sapiens]","1//3"]
[57176,3580,8.67,9.62,0.150004900548207,0.446109982982702,"*",0.298682,"VARS2","GO:0005739//mitochondrion","GO:0004832//valine-tRNA ligase activity;GO:0005524//ATP binding;GO:0002161//aminoacyl-tRNA editing activity;GO:0004812//aminoacyl-tRNA ligase activity","GO:0006418//tRNA aminoacylation for protein translation;GO:0006438//valyl-tRNA aminoacylation","K01873//valyl-tRNA synthetase [EC:6.1.1.9]","NP_065175.4//valine--tRNA ligase, mitochondrial isoform 2 precursor [Homo sapiens];NP_001161206.1//valine--tRNA ligase, mitochondrial isoform 1 [Homo sapiens]","1//3;2//1;5"]
[51329,1343,49.25,54.6,0.148777226576114,0.074970085002798,"*",0.0335474,"ARL6IP4","NA","NA","NA","K13170//splicing factor, arginine/serine-rich 18;K13114//pinin;K13165//splicing factor, arginine/serine-rich 12;K17498//transcription factor SPN1","XP_018893876.1//PREDICTED: ADP-ribosylation factor-like protein 6-interacting protein 4 isoform X3 [Gorilla gorilla gorilla];XP_009424768.1//PREDICTED: ADP-ribosylation factor-like protein 6-interacting protein 4 isoform X1 [Pan troglodytes];XP_009424771.1//PREDICTED: ADP-ribosylation factor-like protein 6-interacting protein 4 isoform X4 [Pan troglodytes];XP_018893877.1//PREDICTED: ADP-ribosylation factor-like protein 6-interacting protein 4 isoform X4 [Gorilla gorilla gorilla];XP_009424769.1//PREDICTED: ADP-ribosylation factor-like protein 6-interacting protein 4 isoform X2 [Pan troglodytes]","1//3;3//A2MP1;2//1"]
[252839,1603,55.99,62.06,0.148494516815727,0.0262992657696031,"*",0.01020426,"TMEM9","GO:0005765//lysosomal membrane;GO:0005770//late endosome;GO:0031902//late endosome membrane;GO:0016021//integral component of membrane;GO:0005764//lysosome","NA","GO:0006810//transport","K09067//achaete-scute complex protein;K06013//STE24 endopeptidase [EC:3.4.24.84]","XP_012357475.1//PREDICTED: transmembrane protein 9 isoform X1 [Nomascus leucogenys];XP_003264578.1//PREDICTED: transmembrane protein 9 isoform X2 [Nomascus leucogenys]","4;1//3"]
[102724231,772,0.74,0.82,0.148098638989134,0.858465450774374,"*",0.787688,"LINC00694","NA","NA","NA","K10798//poly [ADP-ribose] polymerase [EC:2.4.2.30];K16882//protein piccolo","NP_001338409.1//putative uncharacterized protein LINC00694 [Homo sapiens]","1//3"]
[3835,2161,48.88,54.14,0.147450602396234,0.0164700462380301,"*",0.0060296,"KIF22","GO:0072686//mitotic spindle;GO:0005634//nucleus;GO:0005874//microtubule;GO:0005829//cytosol;GO:0000785//chromatin;GO:0016607//nuclear speck;GO:0000776//kinetochore;GO:0005871//kinesin complex","GO:0003677//DNA binding;GO:0005524//ATP binding;GO:0003777//microtubule motor activity;GO:0008017//microtubule binding;GO:0016887//ATPase activity","GO:0000278//mitotic cell cycle;GO:0007018//microtubule-based movement;GO:0006281//DNA repair;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0007080//mitotic metaphase plate congression;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0007062//sister chromatid cohesion;GO:0051310//metaphase plate congression","K10403//kinesin family member 22","NP_015556.1//kinesin-like protein KIF22 isoform 1 [Homo sapiens]","1//3;2//1"]
[5031,2441,7.66,8.48,0.146719872638242,0.457794720416125,"*",0.30854,"P2RY6","GO:0016323//basolateral plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016324//apical plasma membrane;GO:0005886//plasma membrane","GO:0045028//G-protein coupled purinergic nucleotide receptor activity;GO:0045029//UDP-activated nucleotide receptor activity;GO:0004930//G-protein coupled receptor activity","GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0030321//transepithelial chloride transport;GO:0071407//cellular response to organic cyclic compound;GO:0071380//cellular response to prostaglandin E stimulus;GO:0014911//positive regulation of smooth muscle cell migration","K04272//purinergic receptor P2Y, G protein-coupled, 6","XP_012312354.2//P2Y purinoceptor 6 isoform X1 [Aotus nancymaae];XP_017833296.1//PREDICTED: P2Y purinoceptor 6 isoform X1 [Callithrix jacchus];NP_001264137.1//P2Y purinoceptor 6 isoform 2 [Homo sapiens]","1//3;2//1"]
[28989,1461,35.83,39.65,0.146152822380605,0.098502474879227,"*",0.0459522,"NTMT1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0008168//methyltransferase activity;GO:0071885//N-terminal protein N-methyltransferase activity;GO:0008276//protein methyltransferase activity;GO:0042054//histone methyltransferase activity","GO:0016571//histone methylation;GO:0007059//chromosome segregation;GO:0018016//N-terminal peptidyl-proline dimethylation;GO:0035570//N-terminal peptidyl-serine methylation;GO:0018011//N-terminal peptidyl-alanine methylation;GO:0018013//N-terminal peptidyl-glycine methylation;GO:0035573//N-terminal peptidyl-serine trimethylation;GO:0007051//spindle organization;GO:0006480//N-terminal protein amino acid methylation;GO:0035568//N-terminal peptidyl-proline methylation;GO:0035572//N-terminal peptidyl-serine dimethylation;GO:0018012//N-terminal peptidyl-alanine trimethylation","K16219//protein N-terminal methyltransferase [EC:2.1.1.244]","NP_054783.2//N-terminal Xaa-Pro-Lys N-methyltransferase 1 isoform a [Homo sapiens];EAW87894.1//chromosome 9 open reading frame 32, isoform CRA_b, partial [Homo sapiens]","1//3;3//A2MP1"]
[1196,2140,13.94,15.42,0.145572204046611,0.242438714342984,"*",0.1362902,"CLK2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0016607//nuclear speck","GO:0004713//protein tyrosine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0042802//identical protein binding","GO:0043484//regulation of RNA splicing;GO:0010212//response to ionizing radiation;GO:0006468//protein phosphorylation;GO:0032526//response to retinoic acid;GO:0045721//negative regulation of gluconeogenesis;GO:0046777//protein autophosphorylation","K08823//CDC-like kinase [EC:2.7.12.1]","ERE92257.1//dual specificity protein kinase CLK2 [Cricetulus griseus];EDL15234.1//CDC-like kinase 2, isoform CRA_b, partial [Mus musculus];XP_017375283.1//PREDICTED: dual specificity protein kinase CLK2 isoform X1 [Cebus capucinus imitator]","1//3;3//A2MP1"]
[284254,1914,0.38,0.42,0.144389909335175,1.01995750333162,"*",0.996588,"DYNAP","GO:0016021//integral component of membrane","NA","NA","K10955//mucin-2","XP_006143512.2//PREDICTED: LOW QUALITY PROTEIN: dynactin-associated protein [Tupaia chinensis];XP_017496475.1//PREDICTED: LOW QUALITY PROTEIN: mucin-22-like [Manis javanica]","1//3;2//1"]
[81853,1004,77.92,86.09,0.143851990070903,0.0642238945891783,"*",0.0280874,"TMEM14B","GO:0016021//integral component of membrane","NA","NA","K22069//LYR motif-containing protein 4;K12581//CCR4-NOT transcription complex subunit 7/8;K04487//cysteine desulfurase [EC:2.8.1.7]","NP_001273417.1//transmembrane protein 14B isoform d [Homo sapiens];NP_001121183.1//transmembrane protein 14B isoform b [Homo sapiens];EAW55278.1//transmembrane protein 14B, isoform CRA_c, partial [Homo sapiens];NP_001273418.1//transmembrane protein 14B isoform e [Homo sapiens];NP_001273413.1//transmembrane protein 14B isoform c [Homo sapiens]","1//3;4;2//1"]
[28973,1536,49.79,55,0.143575603233335,0.0551029596498906,"*",0.0236466,"MRPS18B","GO:0005840//ribosome;GO:0005654//nucleoplasm;GO:0005763//mitochondrial small ribosomal subunit;GO:0005743//mitochondrial inner membrane;GO:0030054//cell junction;GO:0005739//mitochondrion","GO:0003735//structural constituent of ribosome","GO:0032543//mitochondrial translation;GO:0006412//translation;GO:0070126//mitochondrial translational termination;GO:0070125//mitochondrial translational elongation","K16174//small subunit ribosomal protein S18b, mitochondrial","XP_004065427.1//PREDICTED: LOW QUALITY PROTEIN: 28S ribosomal protein S18b, mitochondrial [Gorilla gorilla gorilla]","3//A2MP1"]
[114790,3629,10.06,11.11,0.143228511583565,0.213944146601942,"*",0.1158786,"STK11IP","GO:0005765//lysosomal membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0035578//azurophil granule lumen;GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0019901//protein kinase binding","GO:0008104//protein localization;GO:0043312//neutrophil degranulation","K19475//WAS/WASL-interacting protein;K02184//formin 2;K05748//WAS protein family, member 2","Q8N1F8.3//RecName: Full=Serine/threonine-protein kinase 11-interacting protein; AltName: Full=LKB1-interacting protein 1","3//A2MP1"]
[5552,1529,46.13,50.94,0.143093667208539,0.0967629401856585,"*",0.0450256,"SRGN","GO:0031093//platelet alpha granule lumen;GO:0005615//extracellular space;GO:0005794//Golgi apparatus;GO:0042588//zymogen granule;GO:0005576//extracellular region;GO:0042629//mast cell granule;GO:0000139//Golgi membrane","GO:0005518//collagen binding","GO:0033373//maintenance of protease location in mast cell secretory granule;GO:0030502//negative regulation of bone mineralization;GO:0033382//maintenance of granzyme B location in T cell secretory granule;GO:0033368//protease localization to mast cell secretory granule;GO:0008626//granzyme-mediated apoptotic signaling pathway;GO:0033364//mast cell secretory granule organization;GO:0002576//platelet degranulation;GO:0016485//protein processing;GO:0031214//biomineral tissue development;GO:0050710//negative regulation of cytokine secretion;GO:0033371//T cell secretory granule organization","K06849//proteoglycan peptide core protein","NP_002718.2//serglycin isoform 1 precursor [Homo sapiens];NP_001307983.1//serglycin isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[9266,4623,22.02,24.3,0.142141844928774,0.02378303008,"*",0.00911926,"CYTH2","NA","GO:0005086//ARF guanyl-nucleotide exchange factor activity","GO:0032012//regulation of ARF protein signal transduction","K18441//cytohesin","XP_003269786.1//PREDICTED: cytohesin-2 isoform X1 [Nomascus leucogenys];XP_003269785.1//PREDICTED: cytohesin-2 isoform X2 [Nomascus leucogenys]","6;5"]
[54494,2019,3.5,3.86,0.141245925435751,0.624706852459016,"*",0.50097,"C11orf71","NA","NA","NA","NA","NP_001258491.1//uncharacterized protein C11orf71 isoform 1 [Homo sapiens];NP_061894.2//uncharacterized protein C11orf71 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[57116,1381,1.46,1.61,0.1410923192346,1.02150639516647,"*",0.994904,"ZNF695","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","XP_021565913.1//zinc finger protein 208-like [Carlito syrichta];NP_001191150.1//zinc finger protein 695 isoform 2 [Homo sapiens]","4;1//3"]
[54543,796,71.4,78.72,0.140806146422778,0.122574295314522,"*",0.0592844,"TOMM7","GO:0005742//mitochondrial outer membrane translocase complex;GO:0031307//integral component of mitochondrial outer membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane","GO:0008320//protein transmembrane transporter activity","GO:0098779//positive regulation of mitophagy in response to mitochondrial depolarization;GO:0006626//protein targeting to mitochondrion;GO:0045040//protein import into mitochondrial outer membrane;GO:0031647//regulation of protein stability;GO:1903955//positive regulation of protein targeting to mitochondrion;GO:0030150//protein import into mitochondrial matrix;GO:0016236//macroautophagy","K17771//mitochondrial import receptor subunit TOM7","XP_012925743.2//mitochondrial import receptor subunit TOM7 homolog [Heterocephalus glaber]","3//A2MP1"]
[10607,2618,20.36,22.43,0.139692059010577,0.130422581665607,"*",0.0642152,"TBL3","GO:0034388//Pwp2p-containing subcomplex of 90S preribosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0032040//small-subunit processome;GO:0005730//nucleolus","GO:0030515//snoRNA binding;GO:0003723//RNA binding","GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006364//rRNA processing","K14555//U3 small nucleolar RNA-associated protein 13","BAD92410.1//transducin beta-like 3 variant, partial [Homo sapiens]","2//1"]
[84836,2130,26.53,29.22,0.139331502574802,0.0687922747480483,"*",0.0303394,"ABHD14B","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005829//cytosol","GO:0016787//hydrolase activity","GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0050427//3'-phosphoadenosine 5'-phosphosulfate metabolic process","K13706//abhydrolase domain-containing protein 14","XP_004034308.1//PREDICTED: protein ABHD14B isoform X1 [Gorilla gorilla gorilla];AAH50650.1//ABHD14B protein, partial [Homo sapiens];NP_001241682.1//protein ABHD14B isoform 3 [Homo sapiens]","1//3;2//1"]
[116840,3529,21.98,24.2,0.138815661212726,0.0873556326419214,"*",0.040074,"CNTROB","GO:0005814//centriole;GO:0005829//cytosol;GO:0005813//centrosome","GO:0019904//protein domain specific binding","GO:1902410//mitotic cytokinetic process;GO:0051299//centrosome separation;GO:0007099//centriole replication","K16468//centrobin","BAF85765.1//unnamed protein product [Homo sapiens];NP_001340131.1//centrobin isoform delta [Homo sapiens];NP_444279.2//centrobin isoform alpha [Homo sapiens];NP_001340134.1//centrobin isoform epsilon [Homo sapiens];NP_001032221.1//centrobin isoform beta [Homo sapiens];NP_001317053.1//centrobin isoform gamma [Homo sapiens]","6;4;1//3;2//1"]
[63905,1279,96.69,106.44,0.138601821241519,0.0276759802888318,"*",0.01079734,"MANBAL","GO:0016021//integral component of membrane","NA","NA","K09291//nucleoprotein TPR","XP_011784469.1//PREDICTED: protein MANBAL isoform X1 [Colobus angolensis palliatus]","1//3;3//A2MP1"]
[340562,2167,0.3,0.33,0.137503523749935,0.877313447874357,"*",0.811298,"SATL1","GO:0005829//cytosol","GO:0019809//spermidine binding;GO:0004145//diamine N-acetyltransferase activity","GO:0032918//spermidine acetylation;GO:0046208//spermine catabolic process","K19017//interphotoreceptor matrix proteoglycan 2","NP_001012998.2//spermidine/spermine N(1)-acetyltransferase-like protein 1 [Homo sapiens]","2//1"]
[8233,1512,5.42,5.96,0.13701947910829,0.640324101613571,"*",0.484432,"ZRSR2","GO:0005654//nucleoplasm;GO:0089701//U2AF;GO:0005689//U12-type spliceosomal complex","GO:0046872//metal ion binding;GO:0030628//pre-mRNA 3'-splice site binding","GO:0000398//mRNA splicing, via spliceosome;GO:0000245//spliceosomal complex assembly;GO:0008380//RNA splicing","K13169//splicing factor, arginine/serine-rich 17","NP_005080.1//U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2 [Homo sapiens]","3//A2MP1"]
[57128,1193,32.49,35.71,0.136332390256582,0.0158206539907232,"*",0.00576512,"LYRM4","GO:0005759//mitochondrial matrix;GO:0016604//nuclear body;GO:0005739//mitochondrion","NA","GO:0044281//small molecule metabolic process","K22069//LYR motif-containing protein 4","EAW55178.1//chromosome 6 open reading frame 149, isoform CRA_c, partial [Homo sapiens];EAW55176.1//chromosome 6 open reading frame 149, isoform CRA_a, partial [Homo sapiens]","1//3;2//1;5"]
[1291,4246,9.24,10.15,0.135514970656481,0.221507842696629,"*",0.120946,"COL6A1","NA","NA","NA","K19720//collagen, type III, alpha","ETE70123.1//Collagen alpha-2(VI) chain, partial [Ophiophagus hannah]","2//1"]
[22818,1893,160.12,175.74,0.134289078212984,1.11678571767241E-4,"*",{"v":2.59516e-05,"d":"2.60E-05"},"COPZ1","GO:0030117//membrane coat;GO:0030126//COPI vesicle coat;GO:0030133//transport vesicle;GO:0005829//cytosol;GO:0005789//endoplasmic reticulum membrane;GO:0000139//Golgi membrane","NA","GO:0006886//intracellular protein transport;GO:1901998//toxin transport;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0016192//vesicle-mediated transport","K20472//coatomer subunit zeta","NP_001258665.1//coatomer subunit zeta-1 isoform 4 [Homo sapiens];NP_001258664.1//coatomer subunit zeta-1 isoform 3 [Homo sapiens];XP_013204176.1//PREDICTED: coatomer subunit zeta-1 [Microtus ochrogaster];NP_001258663.1//coatomer subunit zeta-1 isoform 2 [Homo sapiens]","1//3;2//1"]
[1512,1514,9.36,10.27,0.133855746734791,0.463907400369686,"*",0.314228,"CTSH","GO:1904724//tertiary granule lumen;GO:0034774//secretory granule lumen;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005764//lysosome;GO:0097486//multivesicular body lumen;GO:0097208//alveolar lamellar body;GO:0005829//cytosol;GO:0005576//extracellular region;GO:1904813//ficolin-1-rich granule lumen;GO:0036464//cytoplasmic ribonucleoprotein granule","GO:0004252//serine-type endopeptidase activity;GO:0004175//endopeptidase activity;GO:0030108//HLA-A specific activating MHC class I receptor activity;GO:0008233//peptidase activity;GO:0008656//cysteine-type endopeptidase activator activity involved in apoptotic process;GO:0070324//thyroid hormone binding;GO:0004177//aminopeptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0004197//cysteine-type endopeptidase activity","GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0030335//positive regulation of cell migration;GO:0010813//neuropeptide catabolic process;GO:0070371//ERK1 and ERK2 cascade;GO:0044267//cellular protein metabolic process;GO:0010634//positive regulation of epithelial cell migration;GO:0043312//neutrophil degranulation;GO:0033619//membrane protein proteolysis;GO:0002764//immune response-regulating signaling pathway;GO:0045766//positive regulation of angiogenesis;GO:0031648//protein destabilization;GO:0010815//bradykinin catabolic process;GO:0001656//metanephros development;GO:0001913//T cell mediated cytotoxicity;GO:0019882//antigen processing and presentation;GO:0060448//dichotomous subdivision of terminal units involved in lung branching;GO:0043066//negative regulation of apoptotic process;GO:0032526//response to retinoic acid;GO:0010628//positive regulation of gene expression;GO:0002250//adaptive immune response;GO:2001235//positive regulation of apoptotic signaling pathway;GO:0006508//proteolysis;GO:0006955//immune response;GO:0031638//zymogen activation;GO:0010952//positive regulation of peptidase activity;GO:0097067//cellular response to thyroid hormone stimulus;GO:0043129//surfactant homeostasis;GO:0008284//positive regulation of cell proliferation","K01366//cathepsin H [EC:3.4.22.16]","XP_018866236.1//PREDICTED: pro-cathepsin H isoform X3 [Gorilla gorilla gorilla];NP_004381.2//pro-cathepsin H isoform a preproprotein [Homo sapiens]","1//3;4"]
[9127,2759,0.62,0.68,0.133266530863464,0.837333357762777,"*",0.761012,"P2RX6","GO:0098794//postsynapse;GO:0005887//integral component of plasma membrane;GO:0030054//cell junction;GO:0005639//integral component of nuclear inner membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0004931//extracellularly ATP-gated cation channel activity;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0004888//transmembrane signaling receptor activity;GO:0001614//purinergic nucleotide receptor activity;GO:0015267//channel activity","GO:0006810//transport;GO:0033198//response to ATP;GO:0007165//signal transduction;GO:0007596//blood coagulation;GO:0006936//muscle contraction;GO:0051260//protein homooligomerization","K05221//P2X purinoceptor 6","NP_001336805.1//P2X purinoceptor 6 isoform 4 [Homo sapiens];NP_005437.2//P2X purinoceptor 6 isoform 1 [Homo sapiens];NP_001153026.1//P2X purinoceptor 6 isoform 2 [Homo sapiens];NP_001336803.1//P2X purinoceptor 6 isoform 3 [Homo sapiens]","4;1//3"]
[90378,2396,40.78,44.71,0.132735770526045,0.0417874527407407,"*",0.01730462,"SAMD1","GO:0005576//extracellular region;GO:0005737//cytoplasm","NA","NA","K16628//collagen, type VII, alpha","NP_612361.1//atherin [Homo sapiens]","2//1"]
[8318,1981,23.12,25.34,0.132275126640131,0.167898122346098,"*",0.0867344,"CDC45","GO:0031261//DNA replication preinitiation complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031298//replication fork protection complex;GO:0005656//nuclear pre-replicative complex;GO:0005813//centrosome;GO:0005737//cytoplasm","GO:0003688//DNA replication origin binding;GO:0003697//single-stranded DNA binding;GO:0003682//chromatin binding;GO:0043138//3'-5' DNA helicase activity","GO:1900087//positive regulation of G1/S transition of mitotic cell cycle;GO:1902977//mitotic DNA replication preinitiation complex assembly;GO:0000727//double-strand break repair via break-induced replication;GO:0006260//DNA replication;GO:0006270//DNA replication initiation;GO:0000076//DNA replication checkpoint;GO:0031938//regulation of chromatin silencing at telomere;GO:0006267//pre-replicative complex assembly involved in nuclear cell cycle DNA replication;GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0000082//G1/S transition of mitotic cell cycle","K06628//cell division control protein 45","NP_001171481.1//cell division control protein 45 homolog isoform 1 [Homo sapiens];NP_003495.1//cell division control protein 45 homolog isoform 2 [Homo sapiens];NP_001171482.1//cell division control protein 45 homolog isoform 3 [Homo sapiens]","4;2//1"]
[8878,2917,597.5,654.6,0.13167488928929,{"v":8.46509901754386e-22,"d":"8.47E-22"},"*",{"v":3.62472e-23,"d":"3.62E-23"},"SQSTM1","GO:0005783//endoplasmic reticulum;GO:0005770//late endosome;GO:0000932//P-body;GO:0016234//inclusion body;GO:0005737//cytoplasm;GO:0044754//autolysosome;GO:0005829//cytosol;GO:0005776//autophagosome;GO:0070062//extracellular exosome;GO:0043231//intracellular membrane-bounded organelle;GO:0005654//nucleoplasm;GO:0016605//PML body;GO:0016235//aggresome;GO:0044753//amphisome;GO:0097413//Lewy body;GO:0000407//phagophore assembly site;GO:0097225//sperm midpiece","GO:0042802//identical protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0030971//receptor tyrosine kinase binding;GO:0042803//protein homodimerization activity;GO:0042169//SH2 domain binding;GO:0019901//protein kinase binding;GO:0070530//K63-linked polyubiquitin modification-dependent protein binding;GO:0043130//ubiquitin binding;GO:0005080//protein kinase C binding;GO:0004674//protein serine/threonine kinase activity;GO:0008270//zinc ion binding;GO:0035255//ionotropic glutamate receptor binding;GO:0019899//enzyme binding","GO:0006950//response to stress;GO:0035556//intracellular signal transduction;GO:0035973//aggrephagy;GO:0000422//autophagy of mitochondrion;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0043065//positive regulation of apoptotic process;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0046578//regulation of Ras protein signal transduction;GO:0002376//immune system process;GO:0001934//positive regulation of protein phosphorylation;GO:1903078//positive regulation of protein localization to plasma membrane;GO:0006914//autophagy;GO:0010821//regulation of mitochondrion organization;GO:1905719//protein localization to perinuclear region of cytoplasm;GO:0061635//regulation of protein complex stability;GO:0002931//response to ischemia;GO:0051291//protein heterooligomerization;GO:0016197//endosomal transport;GO:1900273//positive regulation of long-term synaptic potentiation;GO:0030154//cell differentiation;GO:0043066//negative regulation of apoptotic process;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0006915//apoptotic process;GO:0000423//mitophagy;GO:0044130//negative regulation of growth of symbiont in host;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0008104//protein localization;GO:0098780//response to mitochondrial depolarisation;GO:0007032//endosome organization;GO:0016236//macroautophagy","K14381//sequestosome 1","NP_003891.1//sequestosome-1 isoform 1 [Homo sapiens];XP_001153075.1//PREDICTED: sequestosome-1 isoform X1 [Pan troglodytes]","4;1//3"]
[8563,2565,15.89,17.4,0.130968181387571,0.387122771134844,"*",0.242806,"THOC5","GO:0000784//nuclear chromosome, telomeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000347//THO complex;GO:0000445//THO complex part of transcription export complex;GO:0005737//cytoplasm;GO:0000346//transcription export complex","GO:0003729//mRNA binding","GO:0006406//mRNA export from nucleus;GO:0060215//primitive hemopoiesis;GO:0046784//viral mRNA export from host cell nucleus;GO:0006369//termination of RNA polymerase II transcription;GO:0031124//mRNA 3'-end processing;GO:2000002//negative regulation of DNA damage checkpoint;GO:0006405//RNA export from nucleus;GO:0032786//positive regulation of DNA-templated transcription, elongation;GO:0008380//RNA splicing;GO:0030224//monocyte differentiation","K13174//THO complex subunit 5","EAW59807.1//hCG2011153, isoform CRA_a [Homo sapiens]","1//3;4"]
[51654,1996,15.94,17.45,0.130575407106543,0.271800599042646,"*",0.1564036,"CDK5RAP1","GO:0005739//mitochondrion;GO:0005737//cytoplasm","GO:0035597//N6-isopentenyladenosine methylthiotransferase activity;GO:0046872//metal ion binding;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0016740//transferase activity;GO:0019901//protein kinase binding;GO:0032403//protein complex binding","GO:0006400//tRNA modification;GO:0070131//positive regulation of mitochondrial translation;GO:0045664//regulation of neuron differentiation;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0070900//mitochondrial tRNA modification;GO:0007420//brain development;GO:0045903//positive regulation of translational fidelity","K15865//threonylcarbamoyladenosine tRNA methylthiotransferase CDKAL1 [EC:2.8.4.5]","XP_003273580.1//PREDICTED: CDK5 regulatory subunit-associated protein 1 isoform X1 [Nomascus leucogenys];NP_057166.4//CDK5 regulatory subunit-associated protein 1 isoform b [Homo sapiens];XP_003273581.1//PREDICTED: CDK5 regulatory subunit-associated protein 1 isoform X5 [Nomascus leucogenys];NP_001265098.1//CDK5 regulatory subunit-associated protein 1 isoform e [Homo sapiens];XP_012367331.1//PREDICTED: CDK5 regulatory subunit-associated protein 1 isoform X2 [Nomascus leucogenys]","4;1//3;3//A2MP1"]
[5732,2494,0.32,0.35,0.129283016944966,0.890079791442411,"*",0.82823,"PTGER2","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005622//intracellular;GO:0005886//plasma membrane","GO:0004957//prostaglandin E receptor activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0071380//cellular response to prostaglandin E stimulus;GO:0042127//regulation of cell proliferation;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0032496//response to lipopolysaccharide;GO:0032570//response to progesterone","K04259//prostaglandin E receptor 2","NP_000947.2//prostaglandin E2 receptor EP2 subtype [Homo sapiens]","3//A2MP1"]
[116224,3874,4.81,5.26,0.12902590552226,0.460807130998703,"*",0.311378,"FAM122A","NA","NA","NA","NA","NP_612206.4//protein FAM122A [Homo sapiens]",4]
[6595,3634,5.68,6.21,0.1287023387158,{"v":1.35749459041096E-7,"d":"1.36E-07"},"*",{"v":1.985168e-08,"d":"1.99E-08"},"SMARCA2","GO:0005654//nucleoplasm;GO:0045111//intermediate filament cytoskeleton;GO:0016514//SWI/SNF complex","GO:0042393//histone binding;GO:0005524//ATP binding;GO:0001105//RNA polymerase II transcription coactivator activity;GO:0044212//transcription regulatory region DNA binding;GO:0016887//ATPase activity","GO:0030308//negative regulation of cell growth;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0008285//negative regulation of cell proliferation","K11647//SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:3.6.4.-]","XP_014973296.1//PREDICTED: probable global transcription activator SNF2L2 isoform X1 [Macaca mulatta];XP_011811864.1//PREDICTED: probable global transcription activator SNF2L2 isoform X3 [Colobus angolensis palliatus];NP_001276329.1//probable global transcription activator SNF2L2 isoform f precursor [Homo sapiens];NP_001276327.1//probable global transcription activator SNF2L2 isoform d [Homo sapiens];BAA05142.1//transcriptional activator hSNF2a [Homo sapiens]","1//3;4;3//A2MP1"]
[387787,2330,1.61,1.76,0.12851474052268,0.778059630822065,"*",0.68079,"LIPT2","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0033819//lipoyl(octanoyl) transferase activity;GO:0016874//ligase activity","GO:0006464//cellular protein modification process;GO:0034641//cellular nitrogen compound metabolic process;GO:0009249//protein lipoylation;GO:0009107//lipoate biosynthetic process","K03801//lipoyl(octanoyl) transferase [EC:2.3.1.181]","XP_008965688.2//PREDICTED: putative lipoyltransferase 2, mitochondrial isoform X2 [Pan paniscus];NP_001316871.1//putative lipoyltransferase 2, mitochondrial isoform 3 precursor [Homo sapiens];EAW74939.1//hCG27406, isoform CRA_a [Homo sapiens]","1//3;2//1"]
[51668,614,34.36,37.55,0.12808287126317,0.449611039358329,"*",0.301786,"HSPB11","GO:0030992//intraciliary transport particle B;GO:0070062//extracellular exosome;GO:0005929//cilium;GO:0097542//ciliary tip;GO:0005813//centrosome","GO:0046872//metal ion binding","GO:0030324//lung development;GO:0042073//intraciliary transport;GO:0070986//left/right axis specification;GO:0007507//heart development;GO:0035735//intraciliary transport involved in cilium assembly;GO:0007224//smoothened signaling pathway;GO:0001501//skeletal system development","K19369//heat shock protein beta-11","XP_008966123.1//PREDICTED: intraflagellar transport protein 25 homolog isoform X1 [Pan paniscus]","1//3;3//A2MP1"]
[79096,1690,20.54,22.44,0.127636494290598,0.397374329491525,"*",0.256848,"C11orf49","NA","NA","NA","NA","NP_001265151.1//UPF0705 protein C11orf49 isoform 5 [Homo sapiens];NP_001003677.1//UPF0705 protein C11orf49 isoform 2 [Homo sapiens];NP_077018.1//UPF0705 protein C11orf49 isoform 3 [Homo sapiens];XP_008541417.1//PREDICTED: UPF0705 protein C11orf49 homolog isoform X2 [Equus przewalskii];NP_001003678.1//UPF0705 protein C11orf49 isoform 4 [Homo sapiens]","1//3;4;2//1"]
[27349,2086,11.1,12.12,0.126830022235483,0.462551221173422,"*",0.312904,"MCAT","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0003723//RNA binding;GO:0016740//transferase activity;GO:0004314//[acyl-carrier-protein] S-malonyltransferase activity","GO:0006635//fatty acid beta-oxidation;GO:0008152//metabolic process;GO:0006633//fatty acid biosynthetic process","K00645//[acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]","XP_006934209.1//PREDICTED: malonyl-CoA-acyl carrier protein transacylase, mitochondrial isoform X2 [Felis catus];NP_775738.3//malonyl-CoA-acyl carrier protein transacylase, mitochondrial isoform a precursor [Homo sapiens]","4;3//A2MP1"]
[81544,3235,2.07,2.26,0.126692004915862,0.661405455296367,"*",0.541372,"GDPD5","GO:0030424//axon;GO:0030426//growth cone;GO:0097038//perinuclear endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0043025//neuronal cell body","GO:0047389//glycerophosphocholine phosphodiesterase activity;GO:0008889//glycerophosphodiester phosphodiesterase activity","GO:0045666//positive regulation of neuron differentiation;GO:0021895//cerebral cortex neuron differentiation;GO:0048505//regulation of timing of cell differentiation;GO:0045746//negative regulation of Notch signaling pathway;GO:0031175//neuron projection development;GO:0021522//spinal cord motor neuron differentiation;GO:0006629//lipid metabolic process;GO:0045787//positive regulation of cell cycle","K01124//glycerophosphoinositol inositolphosphodiesterase [EC:3.1.4.43]","NP_110419.5//glycerophosphodiester phosphodiesterase domain-containing protein 5 isoform 1 [Homo sapiens];XP_010365096.1//PREDICTED: glycerophosphodiester phosphodiesterase domain-containing protein 5 isoform X3 [Rhinopithecus roxellana];XP_010810998.1//PREDICTED: glycerophosphodiester phosphodiesterase domain-containing protein 5 isoform X3 [Bos taurus]","1//3;7"]
[4034,3255,16.07,17.54,0.126278818769639,0.18635057283189,"*",0.0983316,"LRCH4","GO:0016323//basolateral plasma membrane;GO:0016605//PML body;GO:0016021//integral component of membrane;GO:0005737//cytoplasm","NA","GO:0007399//nervous system development;GO:0007165//signal transduction;GO:0045199//maintenance of epithelial cell apical/basal polarity","K10130//leucine-rich repeats and death domain-containing protein","EAW76519.1//leucine-rich repeats and calponin homology (CH) domain containing 4, isoform CRA_a [Homo sapiens];NP_001276863.1//leucine-rich repeat and calponin homology domain-containing protein 4 isoform 2 [Homo sapiens]","1//3;4"]
[84957,3458,5.7,6.22,0.125952661078498,0.428834167330677,"*",0.283008,"RELT","GO:0070062//extracellular exosome;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005737//cytoplasm","GO:0005031//tumor necrosis factor-activated receptor activity","GO:0007275//multicellular organism development;GO:0097190//apoptotic signaling pathway;GO:0042127//regulation of cell proliferation;GO:0006955//immune response;GO:0032496//response to lipopolysaccharide;GO:0042981//regulation of apoptotic process;GO:0006954//inflammatory response","K05156//tumor necrosis factor receptor superfamily member 19-like","EAW74895.1//tumor necrosis factor receptor superfamily, member 19-like, isoform CRA_c [Homo sapiens]","1//3;3//A2MP1"]
[23378,1762,12.16,13.26,0.124937546669002,0.445793202543482,"*",0.298442,"RRP8","GO:0033553//rDNA heterochromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005677//chromatin silencing complex;GO:0005886//plasma membrane","GO:0008757//S-adenosylmethionine-dependent methyltransferase activity;GO:0003723//RNA binding;GO:0008168//methyltransferase activity;GO:0035064//methylated histone binding","GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:0006351//transcription, DNA-templated;GO:0046015//regulation of transcription by glucose;GO:0006364//rRNA processing;GO:0042149//cellular response to glucose starvation;GO:0071158//positive regulation of cell cycle arrest;GO:0016569//covalent chromatin modification;GO:0000183//chromatin silencing at rDNA","K14850//ribosomal RNA-processing protein 8 [EC:2.1.1.287]","NP_056139.1//ribosomal RNA-processing protein 8 [Homo sapiens]","3//A2MP1"]
[4802,2134,27.34,29.81,0.124783132385109,0.10821434669487,"*",0.0512416,"NFYC","GO:0090575//RNA polymerase II transcription factor complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016602//CCAAT-binding factor complex;GO:0032993//protein-DNA complex","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003713//transcription coactivator activity;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0008134//transcription factor binding","GO:0006457//protein folding;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006355//regulation of transcription, DNA-templated;GO:0045540//regulation of cholesterol biosynthetic process","K08066//nuclear transcription factor Y, gamma","BAD92212.1//nuclear transcription factor Y, gamma variant, partial [Homo sapiens];NP_001136062.1//nuclear transcription factor Y subunit gamma isoform 5 [Homo sapiens];XP_016815513.1//PREDICTED: nuclear transcription factor Y subunit gamma isoform X1 [Pan troglodytes];XP_009453310.2//PREDICTED: nuclear transcription factor Y subunit gamma isoform X2 [Pan troglodytes]","4;1//3"]
[7137,866,2.11,2.3,0.12439086223719,0.841407210895584,"*",0.765768,"TNNI3","GO:0005829//cytosol;GO:0097512//cardiac myofibril;GO:0005861//troponin complex;GO:0030017//sarcomere;GO:1990584//cardiac Troponin complex","GO:0051015//actin filament binding;GO:0019855//calcium channel inhibitor activity;GO:0030172//troponin C binding;GO:0019901//protein kinase binding;GO:0003779//actin binding;GO:0046872//metal ion binding;GO:0019904//protein domain specific binding;GO:0048306//calcium-dependent protein binding;GO:0031014//troponin T binding","GO:0010882//regulation of cardiac muscle contraction by calcium ion signaling;GO:1903779//regulation of cardiac conduction;GO:0032780//negative regulation of ATPase activity;GO:0030049//muscle filament sliding;GO:0007507//heart development;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0006940//regulation of smooth muscle contraction;GO:0001980//regulation of systemic arterial blood pressure by ischemic conditions;GO:0060048//cardiac muscle contraction;GO:0060047//heart contraction;GO:0001570//vasculogenesis;GO:0003009//skeletal muscle contraction;GO:0006874//cellular calcium ion homeostasis","K12044//troponin I, cardiac muscle","NP_000354.4//troponin I, cardiac muscle [Homo sapiens]",4]
[55070,2312,4.36,4.75,0.123599378441384,0.723391965527489,"*",0.609544,"DET1","GO:0080008//Cul4-RING E3 ubiquitin ligase complex;GO:0005634//nucleus;GO:0031464//Cul4A-RING E3 ubiquitin ligase complex","GO:1990756//protein binding, bridging involved in substrate recognition for ubiquitination;GO:0031625//ubiquitin protein ligase binding;GO:0032403//protein complex binding","GO:0016567//protein ubiquitination;GO:0006461//protein complex assembly;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process","K10571//de-etiolated-1","XP_003986864.1//PREDICTED: DET1 homolog isoform X2 [Felis catus];XP_012499152.1//PREDICTED: DET1 homolog isoform X1 [Propithecus coquereli];NP_001308523.1//DET1 homolog isoform 3 [Homo sapiens];NP_060466.2//DET1 homolog isoform 1 [Homo sapiens]","4;1//3;2//1"]
[2029,1309,76.68,83.51,0.123098628084681,0.0251868381850591,"*",0.00973006,"ENSA","GO:0005654//nucleoplasm;GO:0005737//cytoplasm","GO:0004864//protein phosphatase inhibitor activity;GO:0019870//potassium channel inhibitor activity;GO:0008200//ion channel inhibitor activity;GO:0005102//receptor binding;GO:0019888//protein phosphatase regulator activity;GO:0051721//protein phosphatase 2A binding;GO:0019212//phosphatase inhibitor activity","GO:0006810//transport;GO:0035308//negative regulation of protein dephosphorylation;GO:0000278//mitotic cell cycle;GO:0051301//cell division;GO:0007584//response to nutrient;GO:0009749//response to glucose;GO:0000086//G2/M transition of mitotic cell cycle;GO:0007049//cell cycle;GO:0050796//regulation of insulin secretion","K02539//myeloid leukemia cell differntiation protein MCL-1","NP_996925.1//alpha-endosulfine isoform 1 [Homo sapiens];XP_003817346.2//PREDICTED: alpha-endosulfine isoform X1 [Pan paniscus];NP_004427.1//alpha-endosulfine isoform 3 [Homo sapiens];EAW53534.1//hCG1999134 [Homo sapiens];NP_996928.1//alpha-endosulfine isoform 5 [Homo sapiens];NP_997051.1//alpha-endosulfine isoform 8 [Homo sapiens]","1//3;2//1"]
[79089,2230,27.66,30.12,0.122920613521434,0.348969197242515,"*",0.212322,"TMUB2","GO:0016021//integral component of membrane","NA","NA","K08290//Fas-activated serine/threonine kinase [EC:2.7.11.8]","XP_011523502.1//PREDICTED: transmembrane and ubiquitin-like domain-containing protein 2 isoform X1 [Homo sapiens];AAL55748.1//unknown [Homo sapiens];XP_008974295.2//PREDICTED: transmembrane and ubiquitin-like domain-containing protein 2 isoform X2 [Pan paniscus];XP_020020264.1//LOW QUALITY PROTEIN: transmembrane and ubiquitin-like domain-containing protein 2 [Castor canadensis];XP_011841287.1//PREDICTED: transmembrane and ubiquitin-like domain-containing protein 2 isoform X2 [Mandrillus leucophaeus];XP_008974310.2//PREDICTED: transmembrane and ubiquitin-like domain-containing protein 2 isoform X1 [Pan paniscus];XP_003270795.1//PREDICTED: transmembrane and ubiquitin-like domain-containing protein 2 isoform X1 [Nomascus leucogenys]","1//3;3//A2MP1;2//1"]
[4864,4827,19,20.67,0.121538970207137,0.0757522577777778,"*",0.0339306,"NPC1","GO:0016020//membrane;GO:0005765//lysosomal membrane;GO:0070062//extracellular exosome;GO:0005783//endoplasmic reticulum;GO:0005635//nuclear envelope;GO:0031902//late endosome membrane;GO:0005764//lysosome;GO:0048471//perinuclear region of cytoplasm;GO:0045121//membrane raft;GO:0005887//integral component of plasma membrane;GO:0005794//Golgi apparatus;GO:0005576//extracellular region;GO:0016021//integral component of membrane","GO:0015248//sterol transporter activity;GO:0004872//receptor activity;GO:0015485//cholesterol binding;GO:0004888//transmembrane signaling receptor activity;GO:0001618//virus receptor activity","GO:0007041//lysosomal transport;GO:0006486//protein glycosylation;GO:0071404//cellular response to low-density lipoprotein particle stimulus;GO:0008203//cholesterol metabolic process;GO:0030301//cholesterol transport;GO:0033344//cholesterol efflux;GO:2000189//positive regulation of cholesterol homeostasis;GO:0006897//endocytosis;GO:0006914//autophagy;GO:0042632//cholesterol homeostasis;GO:0071383//cellular response to steroid hormone stimulus;GO:0034383//low-density lipoprotein particle clearance;GO:0042493//response to drug;GO:0046686//response to cadmium ion;GO:0007628//adult walking behavior;GO:0031579//membrane raft organization;GO:0090150//establishment of protein localization to membrane;GO:0060548//negative regulation of cell death;GO:0008206//bile acid metabolic process;GO:0046718//viral entry into host cell;GO:0016242//negative regulation of macroautophagy","K12385//Niemann-Pick C1 protein","BAD92285.1//Niemann-Pick disease, type C1 variant, partial [Homo sapiens]",4]
[6921,1967,26.42,28.74,0.121429595210509,0.200048931285898,"*",0.1068372,"ELOC","NA","NA","NA","K03872//transcription elongation factor B, polypeptide 1","XP_021544320.1//elongin-C isoform X1 [Neomonachus schauinslandi];XP_021574588.1//elongin-C isoform X1 [Carlito syrichta];XP_007116506.1//PREDICTED: transcription elongation factor B polypeptide 1 isoform X1 [Physeter catodon];XP_007116508.1//PREDICTED: transcription elongation factor B polypeptide 1 isoform X3 [Physeter catodon]","1//3;3//A2MP1"]
[11336,2774,15.15,16.47,0.120522761366041,0.271327415153495,"*",0.1560294,"EXOC3","GO:0000145//exocyst","GO:0000149//SNARE binding;GO:0045296//cadherin binding","GO:0051601//exocyst localization;GO:0006887//exocytosis","K06110//exocyst complex component 3","O60645.2//RecName: Full=Exocyst complex component 3; AltName: Full=Exocyst complex component Sec6",4]
[637,2147,16.11,17.51,0.120222589726989,0.343291455467053,"*",0.20775,"BID","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005737//cytoplasm;GO:0032592//integral component of mitochondrial membrane","GO:0005123//death receptor binding;GO:0031625//ubiquitin protein ligase binding;GO:0046982//protein heterodimerization activity","GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:0097284//hepatocyte apoptotic process;GO:0034349//glial cell apoptotic process;GO:0097191//extrinsic apoptotic signaling pathway;GO:0051402//neuron apoptotic process;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0042127//regulation of cell proliferation;GO:0008637//apoptotic mitochondrial changes;GO:0051260//protein homooligomerization;GO:0007420//brain development;GO:0010918//positive regulation of mitochondrial membrane potential;GO:1902230//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage;GO:0043065//positive regulation of apoptotic process;GO:0032355//response to estradiol;GO:0097345//mitochondrial outer membrane permeabilization;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:0001836//release of cytochrome c from mitochondria;GO:1900740//positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway;GO:0032464//positive regulation of protein homooligomerization;GO:0032461//positive regulation of protein oligomerization;GO:0006626//protein targeting to mitochondrion;GO:0042770//signal transduction in response to DNA damage;GO:1901030//positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0042775//mitochondrial ATP synthesis coupled electron transport;GO:0090150//establishment of protein localization to membrane;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0042981//regulation of apoptotic process;GO:2000271//positive regulation of fibroblast apoptotic process","K04726//BH3 interacting domain death agonist","ACA61804.1//Bid precursor, partial [Homo sapiens];NP_932070.1//BH3-interacting domain death agonist isoform 1 [Homo sapiens];AAH22072.2//BID protein, partial [Homo sapiens];XP_011840009.1//PREDICTED: BH3-interacting domain death agonist isoform X2 [Mandrillus leucophaeus]","1//3;3//A2MP1;2//1"]
[5510,1434,31.57,34.31,0.120074865244669,0.105250298593045,"*",0.0496404,"PPP1R7","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005694//chromosome;GO:0005737//cytoplasm","GO:0030234//enzyme regulator activity;GO:0019888//protein phosphatase regulator activity","GO:0007059//chromosome segregation;GO:0035307//positive regulation of protein dephosphorylation","K17550//protein phosphatase 1 regulatory subunit 7","NP_001269343.1//protein phosphatase 1 regulatory subunit 7 isoform 7 [Homo sapiens];XP_010375308.1//PREDICTED: protein phosphatase 1 regulatory subunit 7 isoform X4 [Rhinopithecus roxellana];NP_001269341.1//protein phosphatase 1 regulatory subunit 7 isoform 5 [Homo sapiens];NP_001269342.1//protein phosphatase 1 regulatory subunit 7 isoform 6 [Homo sapiens];XP_005574921.1//PREDICTED: protein phosphatase 1 regulatory subunit 7 isoform X3 [Macaca fascicularis];NP_001271924.1//protein phosphatase 1 regulatory subunit 7 [Macaca fascicularis];XP_010375307.1//PREDICTED: protein phosphatase 1 regulatory subunit 7 isoform X3 [Rhinopithecus roxellana]","1//3;2//1"]
[143244,3849,6.97,7.57,0.119134644117309,0.406103673634525,"*",0.263914,"EIF5AL1","NA","NA","NA","K03263//translation initiation factor 5A","AAH70048.1//EIF5AL1 protein, partial [Homo sapiens]","1//3"]
[4351,2986,19.55,21.22,0.11825604872005,0.361988678984772,"*",0.223212,"MPI","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0008270//zinc ion binding;GO:0004476//mannose-6-phosphate isomerase activity","GO:0000032//cell wall mannoprotein biosynthetic process;GO:0006486//protein glycosylation;GO:0005975//carbohydrate metabolic process;GO:0061611//mannose to fructose-6-phosphate metabolic process;GO:0009298//GDP-mannose biosynthetic process","K01809//mannose-6-phosphate isomerase [EC:5.3.1.8]","NP_002426.1//mannose-6-phosphate isomerase isoform 1 [Homo sapiens];NP_001276084.1//mannose-6-phosphate isomerase isoform 2 [Homo sapiens];NP_001276086.1//mannose-6-phosphate isomerase isoform 4 [Homo sapiens];XP_011519894.1//PREDICTED: mannose-6-phosphate isomerase isoform X1 [Homo sapiens]","1//3;2//1"]
[114049,1257,83,90.09,0.118255639156656,0.0667123425801853,"*",0.0292968,"BUD23","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0048471//perinuclear region of cytoplasm","GO:0003723//RNA binding;GO:0016435//rRNA (guanine) methyltransferase activity;GO:0008168//methyltransferase activity;GO:0046982//protein heterodimerization activity","GO:0031167//rRNA methylation;GO:0006355//regulation of transcription, DNA-templated;GO:0016569//covalent chromatin modification;GO:0006351//transcription, DNA-templated;GO:0070476//rRNA (guanine-N7)-methylation;GO:2000234//positive regulation of rRNA processing","K19306//18S rRNA (guanine1575-N7)-methyltransferase [EC:2.1.1.309]","NP_001189489.1//probable 18S rRNA (guanine-N(7))-methyltransferase isoform 1 [Homo sapiens];NP_059998.2//probable 18S rRNA (guanine-N(7))-methyltransferase isoform 2 [Homo sapiens]","4;2//1"]
[1663,3775,43.3,46.96,0.117065383495965,0.0224676057443658,"*",0.00855018,"DDX11","GO:0070062//extracellular exosome;GO:0031390//Ctf18 RFC-like complex;GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005813//centrosome;GO:0000790//nuclear chromatin;GO:0005737//cytoplasm;GO:0030496//midbody;GO:0005730//nucleolus;GO:0001650//fibrillar center","GO:0003688//DNA replication origin binding;GO:0003677//DNA binding;GO:0005524//ATP binding;GO:0004386//helicase activity;GO:0003690//double-stranded DNA binding;GO:0008186//RNA-dependent ATPase activity;GO:0008026//ATP-dependent helicase activity;GO:0003697//single-stranded DNA binding;GO:0003682//chromatin binding;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0051880//G-quadruplex DNA binding;GO:0003727//single-stranded RNA binding;GO:0045142//triplex DNA binding;GO:0004003//ATP-dependent DNA helicase activity;GO:0046872//metal ion binding;GO:0008094//DNA-dependent ATPase activity","GO:0035563//positive regulation of chromatin binding;GO:0032508//DNA duplex unwinding;GO:1901838//positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter;GO:0072711//cellular response to hydroxyurea;GO:1990700//nucleolar chromatin organization;GO:0036498//IRE1-mediated unfolded protein response;GO:0032091//negative regulation of protein binding;GO:1904976//cellular response to bleomycin;GO:0006974//cellular response to DNA damage stimulus;GO:0006281//DNA repair;GO:0006139//nucleobase-containing compound metabolic process;GO:0006351//transcription, DNA-templated;GO:0016032//viral process;GO:0044806//G-quadruplex DNA unwinding;GO:0007062//sister chromatid cohesion;GO:0072719//cellular response to cisplatin;GO:0007275//multicellular organism development;GO:0031297//replication fork processing;GO:2000781//positive regulation of double-strand break repair;GO:0032079//positive regulation of endodeoxyribonuclease activity;GO:0045876//positive regulation of sister chromatid cohesion","K11273//chromosome transmission fidelity protein 1 [EC:3.6.4.13]","Q92771.3//PUTATIVE PSEUDOGENE: RecName: Full=Putative ATP-dependent RNA helicase DDX12; AltName: Full=CHL1-related protein 2; Short=hCHLR2; AltName: Full=DEAD/H box protein 12;XP_005253388.1//PREDICTED: probable ATP-dependent DNA helicase DDX11 isoform X10 [Homo sapiens];XP_011518897.1//PREDICTED: probable ATP-dependent DNA helicase DDX11 isoform X16 [Homo sapiens];XP_005253390.1//PREDICTED: probable ATP-dependent DNA helicase DDX11 isoform X13 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[83856,7651,0.71,0.77,0.117039421190219,0.199606786297513,"*",0.1065136,"FSD1L","GO:0005622//intracellular","NA","NA","K08285//midline 1 [EC:2.3.2.27];K10647//midline 2 [EC:2.3.2.27];K10655//tripartite motif-containing protein 63 [EC:2.3.2.27]","NP_001274120.1//FSD1-like protein isoform 4 [Homo sapiens];NP_001138785.1//FSD1-like protein isoform 3 [Homo sapiens];NP_001317668.1//FSD1-like protein isoform 6 [Homo sapiens];NP_114125.1//FSD1-like protein isoform 2 [Homo sapiens];NP_001274121.1//FSD1-like protein isoform 5 [Homo sapiens]","4;1//3;2//1"]
[6144,582,411.14,445.73,0.116540326073599,0.00483083724849192,"*",0.00155413,"RPL21","GO:0016020//membrane;GO:0005840//ribosome;GO:0005829//cytosol;GO:0022625//cytosolic large ribosomal subunit","GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome","GO:0006413//translational initiation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0019083//viral transcription;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006412//translation;GO:0006364//rRNA processing","K02889//large subunit ribosomal protein L21e","NP_000973.2//60S ribosomal protein L21 [Homo sapiens]","3//A2MP1"]
[10241,3682,20.13,21.81,0.115642597719411,0.140306068045631,"*",0.0700652,"CALCOCO2","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0031410//cytoplasmic vesicle;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0005829//cytosol;GO:0005776//autophagosome;GO:0000421//autophagosome membrane","GO:0042803//protein homodimerization activity","GO:0098792//xenophagy;GO:1901098//positive regulation of autophagosome maturation;GO:0034341//response to interferon-gamma;GO:0016032//viral process","K21348//calcium-binding and coiled-coil domain-containing protein 2","NP_001248322.1//calcium-binding and coiled-coil domain-containing protein 2 isoform 4 [Homo sapiens];NP_001248319.1//calcium-binding and coiled-coil domain-containing protein 2 isoform 1 [Homo sapiens];NP_005822.1//calcium-binding and coiled-coil domain-containing protein 2 isoform 3 [Homo sapiens];NP_001248320.1//calcium-binding and coiled-coil domain-containing protein 2 isoform 2 [Homo sapiens]","4;1//3"]
[54867,2998,61.49,66.61,0.115386975093947,0.00941863372334609,"*",0.00323526,"TMEM214","GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005881//cytoplasmic microtubule;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","NA","GO:0006915//apoptotic process","NA","NP_060197.4//transmembrane protein 214 isoform 1 [Homo sapiens];NP_001077059.1//transmembrane protein 214 isoform 2 [Homo sapiens]","4;1//3"]
[51172,2209,7.83,8.48,0.115051957272159,0.539938014736842,"*",0.385332,"NAGPA","GO:0005887//integral component of plasma membrane;GO:0032580//Golgi cisterna membrane;GO:0016021//integral component of membrane","GO:0003944//N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase activity","GO:0006622//protein targeting to lysosome;GO:0006486//protein glycosylation;GO:0006464//cellular protein modification process;GO:0005975//carbohydrate metabolic process;GO:0033299//secretion of lysosomal enzymes;GO:0007040//lysosome organization","K01125//N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase [EC:3.1.4.45]","NP_057340.2//N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor [Homo sapiens]","3//A2MP1"]
[51227,850,12.02,13.01,0.11418406600661,0.865105346480789,"*",0.79638,"PIGP","GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0000506//glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex","GO:0017176//phosphatidylinositol N-acetylglucosaminyltransferase activity","GO:0006506//GPI anchor biosynthetic process;GO:0016254//preassembly of GPI anchor in ER membrane","K03861//phosphatidylinositol glycan, class P","BAA96872.1//DSCR5b [Homo sapiens];NP_710148.1//phosphatidylinositol N-acetylglucosaminyltransferase subunit P isoform 1 [Homo sapiens];XP_009200524.2//phosphatidylinositol N-acetylglucosaminyltransferase subunit P isoform X1 [Papio anubis];NP_057514.2//phosphatidylinositol N-acetylglucosaminyltransferase subunit P isoform 3 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[8312,3576,19.54,21.14,0.113544909414298,0.179848402105011,"*",0.094135,"AXIN1","NA","NA","NA","K02157//axin 1","XP_016879233.1//PREDICTED: axin-1 isoform X4 [Homo sapiens];XP_016879232.1//PREDICTED: axin-1 isoform X2 [Homo sapiens]","3//A2MP1;2//1"]
[5833,4067,9.8,10.6,0.113210610447991,0.266361394936709,"*",0.1528068,"PCYT2","GO:0005789//endoplasmic reticulum membrane","GO:0004306//ethanolamine-phosphate cytidylyltransferase activity;GO:0016779//nucleotidyltransferase activity;GO:0003824//catalytic activity","GO:0008654//phospholipid biosynthetic process;GO:0006646//phosphatidylethanolamine biosynthetic process;GO:0009058//biosynthetic process","K00967//ethanolamine-phosphate cytidylyltransferase [EC:2.7.7.14]","XP_017380312.1//PREDICTED: ethanolamine-phosphate cytidylyltransferase isoform X6 [Cebus capucinus imitator];XP_017380309.1//PREDICTED: ethanolamine-phosphate cytidylyltransferase isoform X3 [Cebus capucinus imitator];XP_017380310.1//PREDICTED: ethanolamine-phosphate cytidylyltransferase isoform X4 [Cebus capucinus imitator];NP_002852.1//ethanolamine-phosphate cytidylyltransferase isoform 2 [Homo sapiens];NP_001243363.1//ethanolamine-phosphate cytidylyltransferase isoform 3 [Homo sapiens]","4;1//3;2//1"]
[26099,3694,58.12,62.86,0.11310756916591,0.00756606753633992,"*",0.0025416,"SZRD1","NA","NA","NA","K20069//adaptin ear-binding coat-associated protein 1/2","XP_012669158.1//PREDICTED: SUZ domain-containing protein 1-like [Otolemur garnettii]","1//3;2//1"]
[10907,1484,31.13,33.64,0.111872128785965,0.205622655146716,"*",0.1105476,"TXNL4A","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0005681//spliceosomal complex;GO:0005829//cytosol;GO:0005682//U5 snRNP;GO:0046540//U4/U6 x U5 tri-snRNP complex","NA","GO:0000398//mRNA splicing, via spliceosome;GO:0051301//cell division;GO:0000245//spliceosomal complex assembly;GO:0007049//cell cycle;GO:0000375//RNA splicing, via transesterification reactions","K12859//U5 snRNP protein, DIM1 family","XP_016287227.1//PREDICTED: thioredoxin-like protein 4A isoform X3 [Monodelphis domestica];XP_021006483.1//thioredoxin-like protein 4A isoform X2 [Mus caroli];XP_004861963.2//thioredoxin-like protein 4A isoform X1 [Heterocephalus glaber];NP_001292486.1//thioredoxin-like protein 4A isoform 3 [Homo sapiens];XP_008011890.1//PREDICTED: thioredoxin-like protein 4A isoform X1 [Chlorocebus sabaeus]","4;1//3;2//1"]
[9670,4041,12.6,13.61,0.111243333116716,0.255245536456841,"*",0.1449438,"IPO13","GO:0005634//nucleus;GO:0031965//nuclear membrane;GO:0005737//cytoplasm","GO:0008536//Ran GTPase binding;GO:0008565//protein transporter activity;GO:0008139//nuclear localization sequence binding","GO:0006886//intracellular protein transport;GO:0006606//protein import into nucleus","K15436//transportin-3","BAC98010.2//mKIAA0724 protein, partial [Mus musculus]","3//A2MP1"]
[686,3282,7.28,7.86,0.11059086205991,0.97788886700917,"*",0.941342,"BTD","GO:0005759//mitochondrial matrix;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005576//extracellular region","GO:0047708//biotinidase activity;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0016810//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds","GO:0006807//nitrogen compound metabolic process;GO:0006768//biotin metabolic process;GO:0007417//central nervous system development","K01435//biotinidase [EC:3.5.1.12]","NP_001268653.1//biotinidase isoform 2 [Homo sapiens];NP_000051.1//biotinidase isoform 3 [Homo sapiens];NP_001268655.1//biotinidase isoform 5 [Homo sapiens];XP_005545767.1//PREDICTED: biotinidase isoform X1 [Macaca fascicularis];NP_001268652.1//biotinidase isoform 1 [Homo sapiens]","1//3;4;2//1"]
[10629,2176,11.6,12.52,0.110109756917684,0.46708878102796,"*",0.31688,"TAF6L","NA","NA","NA","K03131//transcription initiation factor TFIID subunit 6","XP_021781330.1//TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L [Papio anubis]","3//A2MP1"]
[8131,2826,35.64,38.45,0.109486261327267,0.127916169368907,"*",0.0624286,"NPRL3","GO:0005765//lysosomal membrane;GO:1990130//GATOR1 complex","GO:0005096//GTPase activator activity","GO:0032007//negative regulation of TOR signaling;GO:0034198//cellular response to amino acid starvation;GO:2000785//regulation of autophagosome assembly;GO:0038202//TORC1 signaling;GO:0048738//cardiac muscle tissue development;GO:0035909//aorta morphogenesis;GO:0060021//palate development;GO:0003281//ventricular septum development","K20406//nitrogen permease regulator 3-like protein","NP_001070818.1//GATOR complex protein NPRL3 isoform 1 [Homo sapiens];XP_007978103.1//PREDICTED: nitrogen permease regulator 3-like protein isoform X4 [Chlorocebus sabaeus];NP_001230177.1//GATOR complex protein NPRL3 isoform 4 [Homo sapiens]","1//3;2//1"]
[344167,2698,1.02,1.1,0.108934371553164,0.805577585329867,"*",0.717778,"FOXI3","GO:0005634//nucleus","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0009653//anatomical structure morphogenesis;GO:0030154//cell differentiation;GO:0006351//transcription, DNA-templated","K09401//forkhead box protein I","NP_001129121.1//forkhead box protein I3 [Homo sapiens]","2//1"]
[64866,5991,7.42,8,0.108580813153921,0.288377480017227,"*",0.1676756,"CDCP1","GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane","NA","NA","K06732//CUB domain-containing protein 1","NP_835488.1//CUB domain-containing protein 1 isoform 2 precursor [Homo sapiens];NP_073753.3//CUB domain-containing protein 1 isoform 1 precursor [Homo sapiens]","4;2//1"]
[4729,937,79.02,85.18,0.108296883572667,0.183151774725799,"*",0.0961736,"NDUFV2","GO:0005747//mitochondrial respiratory chain complex I;GO:0043209//myelin sheath;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0009055//electron transfer activity;GO:0046872//metal ion binding;GO:0051537//2 iron, 2 sulfur cluster binding;GO:0008137//NADH dehydrogenase (ubiquinone) activity;GO:0016491//oxidoreductase activity","GO:0007399//nervous system development;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0048738//cardiac muscle tissue development","K03943//NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:1.6.5.3 1.6.99.3]","NP_066552.2//NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial precursor [Homo sapiens]",4]
[139562,1689,1.55,1.67,0.107579887199815,0.868926589705283,"*",0.80104,"OTUD6A","NA","GO:0004843//thiol-dependent ubiquitin-specific protease activity","GO:1990167//protein K27-linked deubiquitination;GO:0035523//protein K29-linked deubiquitination;GO:1990168//protein K33-linked deubiquitination;GO:0035871//protein K11-linked deubiquitination","K18342//OTU domain-containing protein 6 [EC:3.4.19.12]","NP_997203.1//OTU domain-containing protein 6A [Homo sapiens]","2//1"]
[23038,4819,7.91,8.52,0.107175735753046,0.370935671708006,"*",0.230308,"WDTC1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol","GO:0042393//histone binding;GO:0042826//histone deacetylase binding;GO:0004857//enzyme inhibitor activity","GO:0043687//post-translational protein modification;GO:0006006//glucose metabolic process;GO:0008361//regulation of cell size;GO:0016567//protein ubiquitination;GO:0001701//in utero embryonic development;GO:0035264//multicellular organism growth;GO:0032869//cellular response to insulin stimulus;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045717//negative regulation of fatty acid biosynthetic process;GO:0055082//cellular chemical homeostasis","K11807//WD and tetratricopeptide repeats protein 1","NP_055838.2//WD and tetratricopeptide repeats protein 1 isoform b [Homo sapiens];NP_001263181.1//WD and tetratricopeptide repeats protein 1 isoform a [Homo sapiens]","4;1//3"]
[2147,2009,0.52,0.56,0.106915203916512,0.904545782059001,"*",0.846504,"F2","GO:0070062//extracellular exosome;GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0072562//blood microparticle;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005796//Golgi lumen","GO:0004252//serine-type endopeptidase activity;GO:0001530//lipopolysaccharide binding;GO:0008083//growth factor activity;GO:0005509//calcium ion binding;GO:0008201//heparin binding;GO:0070053//thrombospondin receptor activity;GO:0005102//receptor binding","GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0030449//regulation of complement activation;GO:0048712//negative regulation of astrocyte differentiation;GO:0007596//blood coagulation;GO:2000366//positive regulation of STAT protein import into nucleus;GO:0007166//cell surface receptor signaling pathway;GO:0032967//positive regulation of collagen biosynthetic process;GO:0006465//signal peptide processing;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0051918//negative regulation of fibrinolysis;GO:0030193//regulation of blood coagulation;GO:0070945//neutrophil mediated killing of gram-negative bacterium;GO:0044267//cellular protein metabolic process;GO:1900738//positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0009611//response to wounding;GO:0042730//fibrinolysis;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:1900016//negative regulation of cytokine production involved in inflammatory response;GO:0008360//regulation of cell shape;GO:0006508//proteolysis;GO:0051838//cytolysis by host of symbiont cells;GO:0007275//multicellular organism development;GO:0030194//positive regulation of blood coagulation;GO:0017187//peptidyl-glutamic acid carboxylation;GO:0045861//negative regulation of proteolysis;GO:0007597//blood coagulation, intrinsic pathway;GO:0030168//platelet activation;GO:0030307//positive regulation of cell growth;GO:0010544//negative regulation of platelet activation;GO:0001934//positive regulation of protein phosphorylation;GO:1900182//positive regulation of protein localization to nucleus;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0050900//leukocyte migration;GO:0006953//acute-phase response;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0090218//positive regulation of lipid kinase activity;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0008284//positive regulation of cell proliferation","K01313//coagulation factor II (thrombin) [EC:3.4.21.5]","NP_001298186.1//prothrombin isoform 2 [Homo sapiens];NP_000497.1//prothrombin isoform 1 preproprotein [Homo sapiens]","1//3;4"]
[50,2744,36.7,39.51,0.106437783247095,0.1094096900369,"*",0.051972,"ACO2","GO:0005759//mitochondrial matrix;GO:0043209//myelin sheath;GO:0005739//mitochondrion","GO:0003994//aconitate hydratase activity;GO:0046872//metal ion binding;GO:0005506//iron ion binding;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0051538//3 iron, 4 sulfur cluster binding","GO:0006099//tricarboxylic acid cycle;GO:0035900//response to isolation stress;GO:0006101//citrate metabolic process;GO:0001889//liver development;GO:0006102//isocitrate metabolic process;GO:0006091//generation of precursor metabolites and energy","K01681//aconitate hydratase [EC:4.2.1.3]","NP_001089.1//aconitate hydratase, mitochondrial precursor [Homo sapiens]","2//1"]
[57704,3707,18.7,20.12,0.105592035030528,0.249123632473142,"*",0.1408124,"GBA2","GO:0005790//smooth endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0000139//Golgi membrane","GO:0008422//beta-glucosidase activity;GO:0004348//glucosylceramidase activity","GO:0016139//glycoside catabolic process;GO:0021954//central nervous system neuron development;GO:0006680//glucosylceramide catabolic process;GO:0008206//bile acid metabolic process;GO:0006687//glycosphingolipid metabolic process","K17108//non-lysosomal glucosylceramidase [EC:3.2.1.45]","BAB13431.1//KIAA1605 protein, partial [Homo sapiens];NP_065995.1//non-lysosomal glucosylceramidase isoform 1 [Homo sapiens]","1//3;2//1"]
[11315,921,113.08,121.59,0.104680792936822,0.117676593288941,"*",0.056422,"PARK7","GO:0070062//extracellular exosome;GO:0005759//mitochondrial matrix;GO:0030424//axon;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0000785//chromatin;GO:0098793//presynapse;GO:0005758//mitochondrial intermembrane space;GO:0043005//neuron projection;GO:0044297//cell body;GO:0005913//cell-cell adherens junction;GO:0005829//cytosol","GO:0050681//androgen receptor binding;GO:1903135//cupric ion binding;GO:0005507//copper ion binding;GO:1903136//cuprous ion binding;GO:0051920//peroxiredoxin activity;GO:0045296//cadherin binding","GO:0031397//negative regulation of protein ubiquitination;GO:0032148//activation of protein kinase B activity;GO:1902958//positive regulation of mitochondrial electron transport, NADH to ubiquinone;GO:1903428//positive regulation of reactive oxygen species biosynthetic process;GO:0042177//negative regulation of protein catabolic process;GO:0008344//adult locomotory behavior;GO:0033864//positive regulation of NAD(P)H oxidase activity;GO:0010273//detoxification of copper ion;GO:0030073//insulin secretion;GO:0042593//glucose homeostasis;GO:0051583//dopamine uptake involved in synaptic transmission;GO:0002866//positive regulation of acute inflammatory response to antigenic stimulus;GO:1902177//positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:0018323//enzyme active site formation via L-cysteine sulfinic acid;GO:0006914//autophagy;GO:0070301//cellular response to hydrogen peroxide;GO:1903427//negative regulation of reactive oxygen species biosynthetic process;GO:1903189//glyoxal metabolic process;GO:0042743//hydrogen peroxide metabolic process;GO:0007005//mitochondrion organization;GO:0060081//membrane hyperpolarization;GO:0050787//detoxification of mercury ion;GO:2000277//positive regulation of oxidative phosphorylation uncoupler activity;GO:1903384//negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0036471//cellular response to glyoxal;GO:0051899//membrane depolarization;GO:0050821//protein stabilization;GO:1902236//negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway;GO:0046295//glycolate biosynthetic process","K05687//protein DJ-1 [EC:3.5.1.124]","XP_011904884.1//PREDICTED: protein deglycase DJ-1 isoform X1 [Cercocebus atys]","4;1//3"]
[152007,1862,3.21,3.45,0.104023064543228,0.916421411655012,"*",0.861404,"GLIPR2","GO:0070062//extracellular exosome;GO:0005576//extracellular region;GO:0000139//Golgi membrane","GO:0042803//protein homodimerization activity","GO:0010634//positive regulation of epithelial cell migration;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0010718//positive regulation of epithelial to mesenchymal transition","K19919//cysteine-rich secretory protein;K20674//modular serine protease [EC:3.4.21.-];K19867//LIM domain-binding protein 3;K21596//calmodulin-binding transcription activator","NP_001273943.1//Golgi-associated plant pathogenesis-related protein 1 isoform f [Homo sapiens];NP_001273942.1//Golgi-associated plant pathogenesis-related protein 1 isoform e [Homo sapiens];EAW58315.1//chromosome 9 open reading frame 19, isoform CRA_a, partial [Homo sapiens]","1//3;3//A2MP1"]
[27173,2231,90.5,97.23,0.103483729181067,0.0298484078666667,"*",0.01177194,"SLC39A1","GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane","GO:0022890//inorganic cation transmembrane transporter activity;GO:0005102//receptor binding;GO:0005385//zinc ion transmembrane transporter activity","GO:0048701//embryonic cranial skeleton morphogenesis;GO:0060173//limb development;GO:0001701//in utero embryonic development;GO:0006812//cation transport;GO:0071577//zinc II ion transmembrane transport","K14709//solute carrier family 39 (zinc transporter), member 1/2/3","BAG56898.1//unnamed protein product [Homo sapiens];XP_003259388.1//PREDICTED: zinc transporter ZIP1 isoform X1 [Nomascus leucogenys]","4;1//3"]
[2051,3449,0.54,0.58,0.103093492964103,0.933112579978814,"*",0.882292,"EPHB6","GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0005829//cytosol;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0005524//ATP binding;GO:0004872//receptor activity;GO:0005003//ephrin receptor activity","GO:0001806//type IV hypersensitivity;GO:2000525//positive regulation of T cell costimulation;GO:0050663//cytokine secretion;GO:0050798//activated T cell proliferation;GO:0048013//ephrin receptor signaling pathway;GO:0032092//positive regulation of protein binding","K05114//Eph receptor B6 [EC:2.7.10.1]","NP_004436.4//ephrin type-B receptor 6 isoform a precursor [Homo sapiens]","2//1;5"]
[6697,1466,85.28,91.57,0.102667584458207,0.0846058884604792,"*",0.038463,"SPR","GO:0070062//extracellular exosome;GO:0005654//nucleoplasm;GO:0005829//cytosol","GO:0050661//NADP binding;GO:0004033//aldo-keto reductase (NADP) activity;GO:0004757//sepiapterin reductase activity","GO:0050999//regulation of nitric-oxide synthase activity;GO:0006729//tetrahydrobiopterin biosynthetic process;GO:0055114//oxidation-reduction process;GO:0006809//nitric oxide biosynthetic process","K00072//sepiapterin reductase [EC:1.1.1.153]","NP_003115.1//sepiapterin reductase [Homo sapiens]",4]
[57787,5165,5.99,6.43,0.102262734539162,0.462262870893105,"*",0.31268,"MARK4","GO:0036064//ciliary basal body;GO:0005815//microtubule organizing center;GO:0015630//microtubule cytoskeleton;GO:0005829//cytosol;GO:0005813//centrosome;GO:0043005//neuron projection","GO:0043130//ubiquitin binding;GO:0050321//tau-protein kinase activity;GO:0043015//gamma-tubulin binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0008017//microtubule binding","GO:0007399//nervous system development;GO:0000226//microtubule cytoskeleton organization;GO:0006468//protein phosphorylation;GO:0030010//establishment of cell polarity;GO:0097711//ciliary basal body-plasma membrane docking;GO:0051301//cell division;GO:0007049//cell cycle;GO:0001578//microtubule bundle formation;GO:0043068//positive regulation of programmed cell death","K08798//MAP/microtubule affinity-regulating kinase [EC:2.7.11.1]","NP_113605.2//MAP/microtubule affinity-regulating kinase 4 isoform 2 [Homo sapiens];NP_001186796.1//MAP/microtubule affinity-regulating kinase 4 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[9894,3334,15.24,16.35,0.101427732892123,0.310683589948263,"*",0.1842046,"TELO2","GO:0016020//membrane;GO:0005634//nucleus;GO:0000781//chromosome, telomeric region;GO:0005622//intracellular;GO:0005737//cytoplasm;GO:0031931//TORC1 complex;GO:0031932//TORC2 complex;GO:0034399//nuclear periphery;GO:0005829//cytosol;GO:0016604//nuclear body","GO:0032947//protein complex scaffold activity;GO:0051879//Hsp90 protein binding;GO:0019901//protein kinase binding;GO:0032403//protein complex binding","GO:1904263//positive regulation of TORC1 signaling;GO:0032006//regulation of TOR signaling;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0050821//protein stabilization;GO:1904515//positive regulation of TORC2 signaling","K11137//telomere length regulation protein","NP_057195.2//telomere length regulation protein TEL2 homolog [Homo sapiens]","1//3;3//A2MP1"]
[90441,1710,11.74,12.59,0.100845874608964,0.57247600275767,"*",0.415864,"ZNF622","GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0022625//cytosolic large ribosomal subunit;GO:0030687//preribosome, large subunit precursor","GO:0003723//RNA binding;GO:0008270//zinc ion binding;GO:0003676//nucleic acid binding","GO:0046330//positive regulation of JNK cascade;GO:0043065//positive regulation of apoptotic process;GO:0008631//intrinsic apoptotic signaling pathway in response to oxidative stress;GO:0033674//positive regulation of kinase activity;GO:0042273//ribosomal large subunit biogenesis","K14816//pre-60S factor REI1","XP_006165305.1//PREDICTED: zinc finger protein 622 [Tupaia chinensis]","2//1"]
[100528021,2282,5.56,5.96,0.100227447738654,0.653981506506342,"*",0.497098,"ST20-MTHFS","GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005737//cytoplasm","GO:0005542//folic acid binding;GO:0046872//metal ion binding;GO:0005524//ATP binding;GO:0030272//5-formyltetrahydrofolate cyclo-ligase activity","GO:0006536//glutamate metabolic process;GO:0015942//formate metabolic process;GO:0046657//folic acid catabolic process;GO:0046653//tetrahydrofolate metabolic process;GO:0035999//tetrahydrofolate interconversion;GO:0009396//folic acid-containing compound biosynthetic process;GO:0046655//folic acid metabolic process","K01934//5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2]","NP_001186689.1//ST20-MTHFS protein [Homo sapiens]","1//3"]
[6647,981,157.9,169.21,0.0998036604044963,0.0602921659930716,"*",0.026149,"SOD1","GO:0005615//extracellular space;GO:0031410//cytoplasmic vesicle;GO:0005777//peroxisome;GO:0005737//cytoplasm;GO:0043025//neuronal cell body;GO:0005829//cytosol;GO:0031045//dense core granule;GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0070062//extracellular exosome;GO:0031012//extracellular matrix;GO:1904115//axon cytoplasm;GO:0032839//dendrite cytoplasm;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005758//mitochondrial intermembrane space;GO:0043209//myelin sheath;GO:0005764//lysosome;GO:0043234//protein complex","GO:0004784//superoxide dismutase activity;GO:0048365//Rac GTPase binding;GO:0030346//protein phosphatase 2B binding;GO:0042802//identical protein binding;GO:0005507//copper ion binding;GO:0008270//zinc ion binding;GO:0051087//chaperone binding;GO:0042803//protein homodimerization activity","GO:0006801//superoxide metabolic process;GO:0045859//regulation of protein kinase activity;GO:0008217//regulation of blood pressure;GO:0032930//positive regulation of superoxide anion generation;GO:0006879//cellular iron ion homeostasis;GO:0000303//response to superoxide;GO:0060087//relaxation of vascular smooth muscle;GO:0001819//positive regulation of cytokine production;GO:0002262//myeloid cell homeostasis;GO:0097332//response to antipsychotic drug;GO:0045471//response to ethanol;GO:0007566//embryo implantation;GO:0046677//response to antibiotic;GO:0006302//double-strand break repair;GO:0008090//retrograde axonal transport;GO:0035865//cellular response to potassium ion;GO:0071276//cellular response to cadmium ion;GO:0006309//apoptotic DNA fragmentation;GO:0019430//removal of superoxide radicals;GO:0042493//response to drug;GO:0043524//negative regulation of neuron apoptotic process;GO:0072593//reactive oxygen species metabolic process;GO:0009408//response to heat;GO:0001541//ovarian follicle development;GO:0001975//response to amphetamine;GO:0006749//glutathione metabolic process;GO:0060047//heart contraction;GO:0008089//anterograde axonal transport;GO:0060052//neurofilament cytoskeleton organization;GO:0060088//auditory receptor cell stereocilium organization;GO:0019226//transmission of nerve impulse;GO:0040014//regulation of multicellular organism growth;GO:0034465//response to carbon monoxide;GO:0007283//spermatogenesis;GO:0032287//peripheral nervous system myelin maintenance;GO:1902177//positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:0071318//cellular response to ATP;GO:0010033//response to organic substance;GO:0042554//superoxide anion generation;GO:0043085//positive regulation of catalytic activity;GO:0000187//activation of MAPK activity;GO:0007569//cell aging;GO:0048678//response to axon injury;GO:0001895//retina homeostasis;GO:0046688//response to copper ion;GO:0042542//response to hydrogen peroxide;GO:0007568//aging;GO:0046716//muscle cell cellular homeostasis;GO:0045541//negative regulation of cholesterol biosynthetic process;GO:0007626//locomotory behavior;GO:0043087//regulation of GTPase activity;GO:0031667//response to nutrient levels;GO:0007605//sensory perception of sound;GO:0050665//hydrogen peroxide biosynthetic process;GO:0051881//regulation of mitochondrial membrane potential","K04565//superoxide dismutase, Cu-Zn family [EC:1.15.1.1]","NP_000445.1//superoxide dismutase [Cu-Zn] [Homo sapiens]",4]
[284434,8420,0.42,0.45,0.0995356735509144,0.827634539053295,"*",0.747586,"NWD1","GO:0005829//cytosol;GO:0005682//U5 snRNP;GO:0071011//precatalytic spliceosome;GO:0071013//catalytic step 2 spliceosome","GO:0003723//RNA binding;GO:0005524//ATP binding","GO:0008380//RNA splicing","K11127//telomerase protein component 1;K01064//wingless-type MMTV integration site family, member 9","XP_011526231.1//PREDICTED: NACHT domain- and WD repeat-containing protein 1 isoform X1 [Homo sapiens];NP_001007526.3//NACHT domain- and WD repeat-containing protein 1 isoform 1 [Homo sapiens]","4;1//3;2//1"]
[5700,1586,78.62,84.21,0.0990952008095865,0.101361824719101,"*",0.0474384,"PSMC1","GO:0016020//membrane;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005838//proteasome regulatory particle","GO:0003723//RNA binding;GO:0005524//ATP binding;GO:0036402//proteasome-activating ATPase activity","GO:1901215//negative regulation of neuron death;GO:0030163//protein catabolic process","K03062//26S proteasome regulatory subunit T2","XP_021100874.1//26S protease regulatory subunit 4 [Heterocephalus glaber];EHB02601.1//26S protease regulatory subunit 4, partial [Heterocephalus glaber]","1//3;2//1"]
[100288687,1710,2.69,2.88,0.0984626388856881,0.795538772550956,"*",0.706144,"DUX4","NA","NA","NA","K06237//collagen, type IV, alpha;K16628//collagen, type VII, alpha","SBT59247.1//hypothetical protein POVWA2_093830 [Plasmodium ovale wallikeri];ACN62210.1//DUX4 [Homo sapiens]","2//1"]
[60681,2888,66.24,70.91,0.0982864233594171,0.032921039086072,"*",0.01316924,"FKBP10","GO:0005788//endoplasmic reticulum lumen;GO:0005730//nucleolus;GO:0005737//cytoplasm","GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005509//calcium ion binding;GO:0005528//FK506 binding","GO:0000412//histone peptidyl-prolyl isomerization;GO:0061077//chaperone-mediated protein folding","K09575//FK506-binding protein 9/10 [EC:5.2.1.8]","CAD97695.1//hypothetical protein, partial [Homo sapiens]","3//A2MP1"]
[5917,2154,57.15,61.15,0.0975990003129085,0.103943277316294,"*",0.0488808,"RARS","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0017101//aminoacyl-tRNA synthetase multienzyme complex","GO:0034618//arginine binding;GO:0004814//arginine-tRNA ligase activity;GO:0005524//ATP binding;GO:0000049//tRNA binding;GO:0045296//cadherin binding","GO:0006418//tRNA aminoacylation for protein translation;GO:0006420//arginyl-tRNA aminoacylation","K01887//arginyl-tRNA synthetase [EC:6.1.1.19]","NP_002878.2//arginine--tRNA ligase, cytoplasmic [Homo sapiens]","3//A2MP1"]
[4711,1068,25.59,27.37,0.09701528732551,0.439259501596244,"*",0.292858,"NDUFB5","GO:0005654//nucleoplasm;GO:0005747//mitochondrial respiratory chain complex I;GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion","GO:0008137//NADH dehydrogenase (ubiquinone) activity","GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0055114//oxidation-reduction process","K03961//NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 5","NP_002483.1//NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial isoform 1 precursor [Homo sapiens];NP_001186887.1//NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial isoform 3 precursor [Homo sapiens];NP_001186886.1//NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[126353,2891,44.84,47.94,0.0964436308437061,0.0969069291571448,"*",0.045129,"MISP","GO:0043231//intracellular membrane-bounded organelle;GO:0005856//cytoskeleton;GO:0005925//focal adhesion;GO:0005938//cell cortex;GO:0005886//plasma membrane","GO:0003779//actin binding","GO:0051301//cell division;GO:0007049//cell cycle","K16519//A-kinase anchor protein 2;K06236//collagen, type I, alpha","NP_775752.1//mitotic interactor and substrate of PLK1 [Homo sapiens]","3//A2MP1"]
[51406,1287,26.56,28.39,0.0961277023774669,0.778235454935622,"*",0.68109,"NOL7","GO:0005730//nucleolus;GO:0005739//mitochondrion","GO:0003723//RNA binding","NA","NA","XP_004432243.2//PREDICTED: nucleolar protein 7 [Ceratotherium simum simum]","4;1//3"]
[5201,1324,61.61,65.84,0.0957998001069448,0.218996975342466,"*",0.1190952,"PFDN1","GO:0016272//prefoldin complex;GO:0005737//cytoplasm","GO:0051082//unfolded protein binding;GO:0003700//DNA binding transcription factor activity;GO:0044183//protein binding involved in protein folding","GO:0007010//cytoskeleton organization;GO:0007049//cell cycle","K09548//prefoldin subunit 1","XP_003477193.2//PREDICTED: prefoldin subunit 1 [Cavia porcellus]",4]
[5001,1955,23.88,25.5,0.0946944104814154,0.379309599598796,"*",0.236742,"ORC5","GO:0000808//origin recognition complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000784//nuclear chromosome, telomeric region;GO:0005664//nuclear origin of replication recognition complex;GO:0005829//cytosol","GO:0003688//DNA replication origin binding;GO:0005524//ATP binding;GO:0000166//nucleotide binding","GO:0006260//DNA replication;GO:0000082//G1/S transition of mitotic cell cycle;GO:0006270//DNA replication initiation","K02607//origin recognition complex subunit 5","NP_859531.1//origin recognition complex subunit 5 isoform 2 [Homo sapiens];NP_002544.1//origin recognition complex subunit 5 isoform 1 [Homo sapiens]","3//A2MP1"]
[114822,3795,9.03,9.64,0.0943071587491036,0.468150427438687,"*",0.317864,"RHPN1","GO:0005829//cytosol","NA","GO:0007165//signal transduction","K18040//tyrosine-protein phosphatase non-receptor type 23 [EC:3.1.3.48]","NP_443156.2//rhophilin-1 [Homo sapiens]","2//1"]
[221491,972,37.05,39.54,0.0938393285360119,0.5859995324631,"*",0.42998,"SMIM29","GO:0005576//extracellular region","NA","NA","NA","NP_001008703.1//uncharacterized protein SMIM29 isoform 1 precursor [Homo sapiens]","1//3;4;2//1"]
[51205,1862,8.04,8.57,0.0920997029335713,0.712207912317328,"*",0.59798,"ACP6","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion;GO:0005737//cytoplasm","GO:0052642//lysophosphatidic acid phosphatase activity;GO:0003993//acid phosphatase activity","GO:0002244//hematopoietic progenitor cell differentiation;GO:2001311//lysobisphosphatidic acid metabolic process;GO:0006644//phospholipid metabolic process;GO:0006654//phosphatidic acid biosynthetic process","K14395//lysophosphatidic acid phosphatase type 6 [EC:3.1.3.2]","NP_057445.4//lysophosphatidic acid phosphatase type 6 isoform 1 [Homo sapiens];NP_001310554.1//lysophosphatidic acid phosphatase type 6 isoform 2 [Homo sapiens]","4;1//3"]
[4257,923,692.07,737.69,0.0920967110185441,0.000265728595119497,"*",{"v":6.61244e-05,"d":"6.61E-05"},"MGST1","GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005741//mitochondrial outer membrane;GO:0035577//azurophil granule membrane;GO:0016021//integral component of membrane;GO:0045177//apical part of cell;GO:0005789//endoplasmic reticulum membrane;GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0005778//peroxisomal membrane","GO:0004364//glutathione transferase activity;GO:0043295//glutathione binding;GO:0004602//glutathione peroxidase activity;GO:0016740//transferase activity;GO:0042803//protein homodimerization activity","GO:0042493//response to drug;GO:0010243//response to organonitrogen compound;GO:0006805//xenobiotic metabolic process;GO:0032496//response to lipopolysaccharide;GO:0055114//oxidation-reduction process;GO:0071449//cellular response to lipid hydroperoxide;GO:0033327//Leydig cell differentiation;GO:0043312//neutrophil degranulation;GO:1901687//glutathione derivative biosynthetic process;GO:0070207//protein homotrimerization","K00799//glutathione S-transferase [EC:2.5.1.18]","NP_001254527.1//microsomal glutathione S-transferase 1 isoform c [Homo sapiens];EAW96364.1//microsomal glutathione S-transferase 1, isoform CRA_c [Homo sapiens];XP_009001524.1//PREDICTED: microsomal glutathione S-transferase 1 isoform X1 [Callithrix jacchus]","1//3;4;2//1"]
[28512,2013,5.18,5.52,0.091716169091615,0.689110621896929,"*",0.571728,"NKIRAS1","GO:0016020//membrane;GO:0005737//cytoplasm","GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0007165//signal transduction;GO:0007249//I-kappaB kinase/NF-kappaB signaling","K17197//NF-kappa-B inhibitor-interacting Ras-like protein","XP_015316384.1//PREDICTED: NF-kappa-B inhibitor-interacting Ras-like protein 1 isoform X1 [Bos taurus]","3//A2MP1"]
[79885,2833,3.25,3.46,0.0903323197209076,0.857402977188909,"*",0.785908,"HDAC11","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0000118//histone deacetylase complex;GO:0005886//plasma membrane","GO:0004407//histone deacetylase activity;GO:0016787//hydrolase activity;GO:0032041//NAD-dependent histone deacetylase activity (H3-K14 specific);GO:0008134//transcription factor binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006325//chromatin organization;GO:0014003//oligodendrocyte development;GO:0006351//transcription, DNA-templated;GO:0016575//histone deacetylation","K11418//histone deacetylase 11 [EC:3.5.1.98]","XP_018880133.1//PREDICTED: histone deacetylase 11 isoform X1 [Gorilla gorilla gorilla];XP_017820599.1//PREDICTED: histone deacetylase 11 isoform X2 [Callithrix jacchus];XP_009236662.1//PREDICTED: histone deacetylase 11 isoform X1 [Pongo abelii]","1//3;3//A2MP1;2//1"]
[55696,2352,28.84,30.7,0.0901674910167192,0.299855824850299,"*",0.175551,"RBM22","GO:0071007//U2-type catalytic step 2 spliceosome;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0071006//U2-type catalytic step 1 spliceosome;GO:0000974//Prp19 complex;GO:0005737//cytoplasm;GO:0071013//catalytic step 2 spliceosome;GO:0005681//spliceosomal complex","GO:0003723//RNA binding;GO:0036002//pre-mRNA binding;GO:0046872//metal ion binding;GO:0005487//nucleocytoplasmic transporter activity;GO:0048306//calcium-dependent protein binding;GO:0017070//U6 snRNA binding","GO:0033120//positive regulation of RNA splicing;GO:0000398//mRNA splicing, via spliceosome;GO:0035690//cellular response to drug;GO:0090316//positive regulation of intracellular protein transport;GO:0000060//protein import into nucleus, translocation;GO:0045292//mRNA cis splicing, via spliceosome;GO:0000387//spliceosomal snRNP assembly","K12872//pre-mRNA-splicing factor RBM22/SLT11","XP_005380625.1//PREDICTED: pre-mRNA-splicing factor RBM22 [Chinchilla lanigera]","2//1"]
[30850,3546,35.7,37.98,0.0893158312330351,0.134467454770318,"*",0.0667034,"CDR2L","NA","NA","NA","K16628//collagen, type VII, alpha","NP_055418.2//cerebellar degeneration-related protein 2-like [Homo sapiens]","2//1"]
[116988,3032,27.8,29.56,0.0885613865352811,0.540235029942217,"*",0.386288,"AGAP3","GO:0016020//membrane;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0005096//GTPase activator activity","GO:0007165//signal transduction","K12491//Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1/3","NP_001337033.1//arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 isoform h [Homo sapiens];NP_001036000.1//arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 isoform b [Homo sapiens];NP_001295234.1//arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 isoform e [Homo sapiens];NP_114152.3//arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 isoform a [Homo sapiens];NP_001337032.1//arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 isoform g [Homo sapiens];XP_016801398.1//PREDICTED: arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 isoform X3 [Pan troglodytes];NP_001337031.1//arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 isoform f [Homo sapiens];NP_001295233.1//arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 isoform d [Homo sapiens]","6;1//3;3//A2MP1"]
[1948,4404,0.95,1.01,0.0883558744208469,0.842884479504814,"*",0.767218,"EFNB2","GO:0005887//integral component of plasma membrane;GO:0005925//focal adhesion;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0046875//ephrin receptor binding;GO:0001618//virus receptor activity","GO:0010839//negative regulation of keratinocyte proliferation;GO:0016477//cell migration;GO:0031295//T cell costimulation;GO:0002042//cell migration involved in sprouting angiogenesis;GO:0010977//negative regulation of neuron projection development;GO:0050920//regulation of chemotaxis;GO:0007411//axon guidance;GO:0009653//anatomical structure morphogenesis;GO:0001945//lymph vessel development;GO:0007267//cell-cell signaling;GO:0048013//ephrin receptor signaling pathway;GO:1901216//positive regulation of neuron death;GO:0007155//cell adhesion;GO:0009887//animal organ morphogenesis;GO:1903849//positive regulation of aorta morphogenesis;GO:0048514//blood vessel morphogenesis;GO:2000727//positive regulation of cardiac muscle cell differentiation;GO:0048845//venous blood vessel morphogenesis;GO:0072178//nephric duct morphogenesis;GO:0008284//positive regulation of cell proliferation","K05463//ephrin-B","NP_004084.1//ephrin-B2 precursor [Homo sapiens]","3//A2MP1"]
[2580,4519,15.05,15.99,0.0874064518332675,0.333282599271971,"*",0.200608,"GAK","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005925//focal adhesion;GO:0031982//vesicle;GO:0048471//perinuclear region of cytoplasm;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0045202//synapse","GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0051087//chaperone binding;GO:0030332//cyclin binding","GO:0016191//synaptic vesicle uncoating;GO:0072659//protein localization to plasma membrane;GO:1905224//clathrin-coated pit assembly;GO:0090160//Golgi to lysosome transport;GO:0072583//clathrin-dependent endocytosis;GO:0051085//chaperone cofactor-dependent protein refolding;GO:0007030//Golgi organization;GO:0061024//membrane organization;GO:0072600//establishment of protein localization to Golgi;GO:0010977//negative regulation of neuron projection development;GO:0006898//receptor-mediated endocytosis;GO:0072318//clathrin coat disassembly;GO:0007049//cell cycle;GO:0007029//endoplasmic reticulum organization","K08855//cyclin G-associated kinase [EC:2.7.11.1]","NP_005246.2//cyclin-G-associated kinase isoform 1 [Homo sapiens];NP_001305063.1//cyclin-G-associated kinase isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[26959,2764,8.06,8.56,0.0868309578731796,0.646414621293467,"*",0.48993,"HBP1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016607//nuclear speck","GO:0003723//RNA binding;GO:0003677//DNA binding","GO:0006355//regulation of transcription, DNA-templated;GO:0016055//Wnt signaling pathway;GO:0006351//transcription, DNA-templated;GO:0007050//cell cycle arrest","K21644//HMG box transcription factor 1","XP_004635043.1//PREDICTED: HMG box-containing protein 1 isoform X1 [Octodon degus];XP_009452138.1//PREDICTED: HMG box-containing protein 1 isoform X1 [Pan troglodytes]","1//3;3//A2MP1"]
[2990,2319,15.58,16.54,0.0862640011096054,0.516433493099122,"*",0.360734,"GUSB","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005764//lysosome;GO:0035578//azurophil granule lumen;GO:0005576//extracellular region;GO:1904813//ficolin-1-rich granule lumen;GO:0043202//lysosomal lumen","GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0019904//protein domain specific binding;GO:0005102//receptor binding;GO:0004566//beta-glucuronidase activity","GO:0043312//neutrophil degranulation;GO:0030214//hyaluronan catabolic process;GO:0005975//carbohydrate metabolic process;GO:0006027//glycosaminoglycan catabolic process","K01195//beta-glucuronidase [EC:3.2.1.31]","NP_001280033.1//beta-glucuronidase isoform 3 [Homo sapiens];NP_001271219.1//beta-glucuronidase isoform 2 precursor [Homo sapiens];NP_000172.2//beta-glucuronidase isoform 1 precursor [Homo sapiens];NP_001280034.1//beta-glucuronidase isoform 4 [Homo sapiens]","1//3;3//A2MP1"]
[79629,1166,8.06,8.55,0.0851445812452928,0.741016046724226,"*",0.639378,"OCEL1","NA","NA","NA","K04942//potassium intermediate/small conductance calcium-activated channel subfamily N member 1;K17291//MARVEL domain-containing protein 2","XP_014198046.1//PREDICTED: occludin/ELL domain-containing protein 1 isoform X1 [Pan paniscus]","2//1"]
[8669,2523,28.47,30.19,0.0846282637713598,0.395431264332137,"*",0.255196,"EIF3J","GO:0016282//eukaryotic 43S preinitiation complex;GO:0005829//cytosol;GO:0033290//eukaryotic 48S preinitiation complex;GO:0005852//eukaryotic translation initiation factor 3 complex","GO:0003743//translation initiation factor activity","GO:0006413//translational initiation;GO:0006446//regulation of translational initiation;GO:0001731//formation of translation preinitiation complex","K03245//translation initiation factor 3 subunit J","XP_006883010.1//PREDICTED: eukaryotic translation initiation factor 3 subunit J-A-like [Elephantulus edwardii];NP_001271265.1//eukaryotic translation initiation factor 3 subunit J isoform 3 [Homo sapiens];XP_007962947.1//PREDICTED: eukaryotic translation initiation factor 3 subunit J [Chlorocebus sabaeus]","1//3;3//A2MP1"]
[23508,5217,0.83,0.88,0.0843921872903726,0.846275120945574,"*",0.77094,"TTC9","NA","NA","NA","K19475//WAS/WASL-interacting protein;K05746//enabled;K20638//Rho GTPase-activating protein 17","XP_012359753.1//PREDICTED: tetratricopeptide repeat protein 9A [Nomascus leucogenys]","1//3"]
[91368,1270,38.36,40.65,0.0836526319442592,0.450465012865933,"*",0.302472,"CDKN2AIPNL","GO:0005654//nucleoplasm;GO:0005730//nucleolus","NA","GO:0007165//signal transduction","K12581//CCR4-NOT transcription complex subunit 7/8;K17985//activating molecule in BECN1-regulated autophagy protein 1","XP_022349178.1//LOW QUALITY PROTEIN: CDKN2AIP N-terminal-like protein [Enhydra lutris kenyoni]","2//1"]
[10775,2612,25.15,26.64,0.0830356823783728,0.356822792445125,"*",0.218798,"POP4","GO:0000172//ribonuclease MRP complex;GO:0005654//nucleoplasm;GO:0030681//multimeric ribonuclease P complex;GO:0030677//ribonuclease P complex;GO:0005655//nucleolar ribonuclease P complex","GO:0033204//ribonuclease P RNA binding;GO:0003723//RNA binding;GO:0004526//ribonuclease P activity","GO:0006379//mRNA cleavage;GO:0001682//tRNA 5'-leader removal;GO:0006364//rRNA processing;GO:0008033//tRNA processing","K03538//ribonuclease P protein subunit POP4 [EC:3.1.26.5]","NP_006618.1//ribonuclease P protein subunit p29 [Homo sapiens]","2//1"]
[55735,3316,28.29,29.96,0.0827454470624984,0.251275507277151,"*",0.1422332,"DNAJC11","GO:0070062//extracellular exosome;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0001401//mitochondrial sorting and assembly machinery complex;GO:0061617//MICOS complex","NA","GO:0042407//cristae formation","K09531//DnaJ homolog subfamily C member 11","NP_060668.2//dnaJ homolog subfamily C member 11 [Homo sapiens]","3//A2MP1"]
[4953,2147,78.81,83.44,0.0823604566649776,0.207060722065837,"*",0.1114374,"ODC1","GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm","GO:0004586//ornithine decarboxylase activity;GO:0003824//catalytic activity;GO:0042803//protein homodimerization activity","GO:0006595//polyamine metabolic process;GO:0001822//kidney development;GO:0006521//regulation of cellular amino acid metabolic process;GO:0006596//polyamine biosynthetic process;GO:0042176//regulation of protein catabolic process;GO:0009615//response to virus;GO:0008284//positive regulation of cell proliferation;GO:0033387//putrescine biosynthetic process from ornithine","K01581//ornithine decarboxylase [EC:4.1.1.17]","XP_017506692.1//PREDICTED: ornithine decarboxylase [Manis javanica];NP_002530.1//ornithine decarboxylase isoform 1 [Homo sapiens]","1//3;2//1"]
[5423,1351,7.16,7.58,0.0822382609068354,0.745519650687907,"*",0.644524,"POLB","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005874//microtubule;GO:0043234//protein complex;GO:0005737//cytoplasm;GO:0005876//spindle microtubule","GO:0003677//DNA binding;GO:0003906//DNA-(apurinic or apyrimidinic site) lyase activity;GO:0008017//microtubule binding;GO:0003887//DNA-directed DNA polymerase activity;GO:0016829//lyase activity;GO:0046872//metal ion binding;GO:0003684//damaged DNA binding;GO:0019899//enzyme binding","GO:0051402//neuron apoptotic process;GO:0006284//base-excision repair;GO:0016446//somatic hypermutation of immunoglobulin genes;GO:0010332//response to gamma radiation;GO:0045471//response to ethanol;GO:0048536//spleen development;GO:0006288//base-excision repair, DNA ligation;GO:0016579//protein deubiquitination;GO:0006974//cellular response to DNA damage stimulus;GO:0048872//homeostasis of number of cells;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0006281//DNA repair;GO:0071707//immunoglobulin heavy chain V-D-J recombination;GO:0048535//lymph node development;GO:0006287//base-excision repair, gap-filling;GO:0007568//aging;GO:0006954//inflammatory response;GO:0007435//salivary gland morphogenesis;GO:0055093//response to hyperoxia;GO:0006261//DNA-dependent DNA replication;GO:0006286//base-excision repair, base-free sugar-phosphate removal;GO:0006290//pyrimidine dimer repair","K02330//DNA polymerase beta [EC:2.7.7.7 4.2.99.-]","NP_002681.1//DNA polymerase beta [Homo sapiens]","2//1"]
[9156,3218,9.78,10.35,0.081724397434454,0.656549155691836,"*",0.536164,"EXO1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body","GO:0003677//DNA binding;GO:0004523//RNA-DNA hybrid ribonuclease activity;GO:0045145//single-stranded DNA 5'-3' exodeoxyribonuclease activity;GO:0008409//5'-3' exonuclease activity;GO:0051908//double-stranded DNA 5'-3' exodeoxyribonuclease activity;GO:0004527//exonuclease activity;GO:0046872//metal ion binding;GO:0048256//flap endonuclease activity;GO:0003682//chromatin binding;GO:0035312//5'-3' exodeoxyribonuclease activity","GO:0045190//isotype switching;GO:0000732//strand displacement;GO:0006281//DNA repair;GO:0016446//somatic hypermutation of immunoglobulin genes;GO:0006298//mismatch repair;GO:0006260//DNA replication;GO:0090656//t-circle formation;GO:1901796//regulation of signal transduction by p53 class mediator;GO:0000731//DNA synthesis involved in DNA repair;GO:0051321//meiotic cell cycle;GO:0006310//DNA recombination;GO:0002455//humoral immune response mediated by circulating immunoglobulin","K10746//exonuclease 1 [EC:3.1.-.-]","NP_001306153.1//exonuclease 1 isoform c [Homo sapiens];NP_006018.4//exonuclease 1 isoform b [Homo sapiens];NP_003677.4//exonuclease 1 isoform a [Homo sapiens]","4;1//3;3//A2MP1"]
[150159,1755,1.56,1.65,0.0809199953835675,0.873622415954416,"*",0.806244,"SLC9B1","GO:0097228//sperm principal piece;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005886//plasma membrane","GO:0015385//sodium:proton antiporter activity;GO:0015299//solute:proton antiporter activity","GO:0030317//flagellated sperm motility;GO:0034220//ion transmembrane transport;GO:0007338//single fertilization;GO:0051453//regulation of intracellular pH;GO:0006814//sodium ion transport","K16816//patatin-like phospholipase domain-containing protein 2 [EC:3.1.1.3]","XP_016806465.1//PREDICTED: sodium/hydrogen exchanger 9B1 isoform X1 [Pan troglodytes]","3//A2MP1;2//1"]
[57099,1551,11,11.63,0.0803475730611966,0.66985375486618,"*",0.551516,"AVEN","GO:0016020//membrane;GO:0012505//endomembrane system;GO:0005622//intracellular","NA","GO:0043066//negative regulation of apoptotic process;GO:0006915//apoptotic process","K19475//WAS/WASL-interacting protein;K13199//plasminogen activator inhibitor 1 RNA-binding protein;K14958//kinase suppressor of Ras 1","NP_065104.1//cell death regulator Aven [Homo sapiens]","2//1"]
[81621,2677,2.46,2.6,0.0798533076892146,0.78859118846317,"*",0.698348,"KAZALD1","GO:0005614//interstitial matrix","GO:0005520//insulin-like growth factor binding","GO:0001558//regulation of cell growth;GO:0030154//cell differentiation;GO:0007275//multicellular organism development;GO:0030198//extracellular matrix organization;GO:0001503//ossification","K08784//HtrA serine peptidase 1 [EC:3.4.21.-]","NP_112191.2//kazal-type serine protease inhibitor domain-containing protein 1 isoform a precursor [Homo sapiens];AAG50291.1//FKSG40 [Homo sapiens]","4;1//3"]
[23207,4167,19.49,20.59,0.0792097393743644,0.319941519488416,"*",0.1910556,"PLEKHM2","GO:0010008//endosome membrane","GO:0019894//kinesin binding","GO:0032880//regulation of protein localization;GO:1903527//positive regulation of membrane tubulation;GO:0007030//Golgi organization;GO:0032418//lysosome localization","K15348//pleckstrin homology domain-containing family M member 2","AAH40441.1//PLEKHM2 protein, partial [Homo sapiens]","3//A2MP1"]
[493753,1767,7.34,7.75,0.0784162473183871,0.72280005943978,"*",0.609,"COA5","GO:0005739//mitochondrion","NA","GO:0033617//mitochondrial respiratory chain complex IV assembly","K18178//cytochrome c oxidase assembly factor 5","NP_001008216.1//cytochrome c oxidase assembly factor 5 [Homo sapiens]","2//1"]
[9401,3840,24.69,26.05,0.0773565360230885,0.28843860919367,"*",0.1677292,"RECQL4","GO:0016020//membrane;GO:0005634//nucleus;GO:0000781//chromosome, telomeric region;GO:0005737//cytoplasm","GO:0000405//bubble DNA binding;GO:0061821//telomeric D-loop binding;GO:0005524//ATP binding;GO:0004386//helicase activity;GO:0036310//annealing helicase activity;GO:0009378//four-way junction helicase activity;GO:0043140//ATP-dependent 3'-5' DNA helicase activity;GO:0032357//oxidized purine DNA binding","GO:0061820//telomeric D-loop disassembly;GO:0006281//DNA repair;GO:0006284//base-excision repair;GO:0007275//multicellular organism development;GO:0000733//DNA strand renaturation;GO:0006260//DNA replication;GO:0000724//double-strand break repair via homologous recombination;GO:0032508//DNA duplex unwinding;GO:0000723//telomere maintenance","K10730//ATP-dependent DNA helicase Q4 [EC:3.6.4.12]","NP_004251.3//ATP-dependent DNA helicase Q4 [Homo sapiens]","3//A2MP1"]
[84916,2215,72.24,76.21,0.0771824225355402,0.152987657901204,"*",0.07794,"UTP4","GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0001650//fibrillar center;GO:0005694//chromosome;GO:0034455//t-UTP complex","GO:0003723//RNA binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006364//rRNA processing;GO:0030490//maturation of SSU-rRNA","K14548//U3 small nucleolar RNA-associated protein 4","XP_017706262.1//PREDICTED: U3 small nucleolar RNA-associated protein 4 homolog [Rhinopithecus bieti]","1//3;2//1"]
[84243,3165,17.42,18.37,0.0766070025124849,0.44391928440367,"*",0.296854,"ZDHHC18","GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane","GO:0016409//palmitoyltransferase activity;GO:0019706//protein-cysteine S-palmitoyltransferase activity","GO:0018345//protein palmitoylation;GO:0034613//cellular protein localization","K16675//palmitoyltransferase ZDHHC9/14/18 [EC:2.3.1.225]","NP_115659.1//palmitoyltransferase ZDHHC18 [Homo sapiens]","2//1"]
[11345,1031,33.74,35.56,0.0757953505422043,0.576023787552724,"*",0.41891,"GABARAPL2","GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0031410//cytoplasmic vesicle;GO:0005622//intracellular;GO:0005737//cytoplasm;GO:0005776//autophagosome;GO:0000139//Golgi membrane;GO:0000421//autophagosome membrane","GO:0000149//SNARE binding;GO:0050811//GABA receptor binding;GO:0048487//beta-tubulin binding;GO:0031625//ubiquitin protein ligase binding;GO:0051117//ATPase binding;GO:0008017//microtubule binding","GO:0006891//intra-Golgi vesicle-mediated transport;GO:0061024//membrane organization;GO:0000422//autophagy of mitochondrion;GO:0097352//autophagosome maturation;GO:0006995//cellular response to nitrogen starvation;GO:0032781//positive regulation of ATPase activity;GO:0006914//autophagy;GO:1901799//negative regulation of proteasomal protein catabolic process;GO:0000045//autophagosome assembly;GO:0015031//protein transport;GO:0016236//macroautophagy","K08341//GABA(A) receptor-associated protein","XP_010382367.1//PREDICTED: uncharacterized protein LOC104678726 [Rhinopithecus roxellana]",6]
[143884,3285,1.86,1.96,0.0755510330071768,0.822855642574464,"*",0.74193,"CWF19L2","NA","NA","NA","K21436//ankyrin repeat domain-containing protein 11/12;K13172//serine/arginine repetitive matrix protein 2;K00476//aspartate beta-hydroxylase [EC:1.14.11.16]","NP_689647.2//CWF19-like protein 2 [Homo sapiens]","2//1"]
[23617,1832,0.75,0.79,0.0749620576812222,0.91817318322237,"*",0.863338,"TSSK2","NA","NA","NA","K08811//testis-specific serine kinase [EC:2.7.11.1]","XP_008964883.1//PREDICTED: testis-specific serine/threonine-protein kinase 2 isoform X1 [Pan paniscus]",4]
[7517,2596,24.14,25.42,0.0745383542499374,0.390551963328351,"*",0.245348,"XRCC3","GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0033063//Rad51B-Rad51C-Rad51D-XRCC2 complex;GO:0005657//replication fork;GO:0033065//Rad51C-XRCC3 complex;GO:0048471//perinuclear region of cytoplasm","GO:0003697//single-stranded DNA binding;GO:0000150//recombinase activity;GO:0005524//ATP binding;GO:0008094//DNA-dependent ATPase activity;GO:0003690//double-stranded DNA binding;GO:0000400//four-way junction DNA binding;GO:0008821//crossover junction endodeoxyribonuclease activity","GO:0000722//telomere maintenance via recombination;GO:0010212//response to ionizing radiation;GO:0071140//resolution of mitotic recombination intermediates;GO:0090267//positive regulation of mitotic cell cycle spindle assembly checkpoint;GO:0010824//regulation of centrosome duplication;GO:0090656//t-circle formation;GO:0042148//strand invasion;GO:0007131//reciprocal meiotic recombination;GO:0000707//meiotic DNA recombinase assembly;GO:0006312//mitotic recombination;GO:0036297//interstrand cross-link repair","K10880//DNA-repair protein XRCC3","XP_011806812.1//PREDICTED: DNA repair protein XRCC3 [Colobus angolensis palliatus]","1//3;3//A2MP1"]
[29941,3404,16.95,17.84,0.0738303418965986,0.483910337657592,"*",0.331594,"PKN3","NA","NA","NA","K06071//protein kinase N [EC:2.7.11.13]","XP_017354656.1//PREDICTED: serine/threonine-protein kinase N3 isoform X4 [Cebus capucinus imitator];XP_008974290.1//PREDICTED: serine/threonine-protein kinase N3 [Pan paniscus]","1//3;4"]
[5794,3394,1.53,1.61,0.073529035421965,0.81771412687813,"*",0.735912,"PTPRH","NA","NA","NA","K18034//receptor-type tyrosine-protein phosphatase H [EC:3.1.3.48]","NP_001154912.2//receptor-type tyrosine-protein phosphatase H isoform 2 precursor [Homo sapiens];NP_002833.4//receptor-type tyrosine-protein phosphatase H isoform 1 precursor [Homo sapiens]","4;2//1"]
[4664,3994,5.78,6.08,0.0730018309429066,0.763134811681772,"*",0.664148,"NAB1","GO:0005634//nucleus","GO:0008134//transcription factor binding","GO:0014037//Schwann cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0042552//myelination;GO:0001958//endochondral ossification;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0045682//regulation of epidermis development","NA","XP_017708399.1//PREDICTED: NGFI-A-binding protein 1 isoform X2 [Rhinopithecus bieti];XP_017708398.1//PREDICTED: NGFI-A-binding protein 1 isoform X1 [Rhinopithecus bieti];XP_011791828.1//PREDICTED: NGFI-A-binding protein 1 isoform X5 [Colobus angolensis palliatus]","1//3;3//A2MP1"]
[317662,3149,2.91,3.06,0.072512499784368,0.780113148187709,"*",0.68581,"FAM149B1","NA","NA","NA","NA","BAA76818.1//KIAA0974 protein, partial [Homo sapiens]","1//3"]
[322,2671,10.24,10.76,0.0714623625566241,0.642384982049797,"*",0.486152,"APBB1","GO:0005737//cytoplasm;GO:0043025//neuronal cell body;GO:0030426//growth cone;GO:0042734//presynaptic membrane;GO:0043197//dendritic spine;GO:0045202//synapse;GO:0005886//plasma membrane;GO:0045211//postsynaptic membrane;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:1990761//growth cone lamellipodium;GO:0044304//main axon;GO:0016607//nuclear speck;GO:0030027//lamellipodium;GO:0048471//perinuclear region of cytoplasm;GO:1990812//growth cone filopodium;GO:0043234//protein complex","GO:0042393//histone binding;GO:0001540//amyloid-beta binding;GO:0003682//chromatin binding;GO:0008134//transcription factor binding;GO:0070064//proline-rich region binding;GO:0048156//tau protein binding;GO:0032403//protein complex binding","GO:0006355//regulation of transcription, DNA-templated;GO:0007050//cell cycle arrest;GO:0045893//positive regulation of transcription, DNA-templated;GO:0050760//negative regulation of thymidylate synthase biosynthetic process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006302//double-strand break repair;GO:0043065//positive regulation of apoptotic process;GO:0043967//histone H4 acetylation;GO:0045739//positive regulation of DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0030308//negative regulation of cell growth;GO:0007165//signal transduction;GO:0006351//transcription, DNA-templated;GO:0010976//positive regulation of neuron projection development;GO:0010039//response to iron ion;GO:0006915//apoptotic process;GO:0007409//axonogenesis;GO:0050714//positive regulation of protein secretion;GO:0045944//positive regulation of transcription from RNA polymerase II promoter","K04529//amyloid beta A4 precursor protein-binding family B member 1","XP_011827902.1//PREDICTED: amyloid beta A4 precursor protein-binding family B member 1 isoform X6 [Mandrillus leucophaeus];XP_011809696.1//PREDICTED: amyloid beta A4 precursor protein-binding family B member 1 isoform X2 [Colobus angolensis palliatus];XP_006718278.3//PREDICTED: amyloid beta A4 precursor protein-binding family B member 1 isoform X5 [Homo sapiens];XP_011809697.1//PREDICTED: amyloid beta A4 precursor protein-binding family B member 1 isoform X3 [Colobus angolensis palliatus];CAD98057.1//hypothetical protein, partial [Homo sapiens];XP_004279296.1//PREDICTED: amyloid beta A4 precursor protein-binding family B member 1 isoform X4 [Orcinus orca]","4;2//1"]
[55585,3223,34,35.72,0.0711973340961587,0.293524734692126,"*",0.1712932,"UBE2Q1","GO:0005634//nucleus;GO:0005829//cytosol;GO:0030175//filopodium","GO:0005524//ATP binding;GO:0061631//ubiquitin conjugating enzyme activity","GO:0007617//mating behavior;GO:0009566//fertilization;GO:0001967//suckling behavior;GO:0061458//reproductive system development;GO:0070459//prolactin secretion;GO:0007566//embryo implantation","K10582//ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]","XP_014445213.1//PREDICTED: ubiquitin-conjugating enzyme E2 Q1 [Tupaia chinensis]",6]
[84304,1021,22.59,23.72,0.0704197391529191,0.443888742696629,"*",0.296778,"NUDT22","GO:0005654//nucleoplasm","GO:0016787//hydrolase activity","NA","NA","EAW74208.1//nudix (nucleoside diphosphate linked moiety X)-type motif 22, isoform CRA_e [Homo sapiens];XP_012351909.1//PREDICTED: nucleoside diphosphate-linked moiety X motif 22 isoform X3 [Nomascus leucogenys];EAW74209.1//nudix (nucleoside diphosphate linked moiety X)-type motif 22, isoform CRA_f [Homo sapiens];XP_018891721.1//PREDICTED: nucleoside diphosphate-linked moiety X motif 22 isoform X1 [Gorilla gorilla gorilla]","1//3;3//A2MP1;2//1"]
[219287,9953,0.4,0.42,0.0703893278913977,0.83746885399449,"*",0.76124,"AMER2","GO:0005886//plasma membrane","GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0008013//beta-catenin binding","GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0060828//regulation of canonical Wnt signaling pathway;GO:0016055//Wnt signaling pathway;GO:0048856//anatomical structure development;GO:0007398//ectoderm development","K19407//APC membrane recruitment protein 1","NP_954589.1//APC membrane recruitment protein 2 isoform 2 [Homo sapiens];NP_689917.2//APC membrane recruitment protein 2 isoform 1 [Homo sapiens]","3//A2MP1;2//1"]
[84936,2035,7.68,8.06,0.0696735278068113,0.718351338240761,"*",0.604802,"ZFYVE19","GO:0032154//cleavage furrow;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0030496//midbody","GO:0046872//metal ion binding;GO:0032266//phosphatidylinositol-3-phosphate binding","GO:0044878//mitotic cytokinesis checkpoint;GO:0051301//cell division;GO:0009838//abscission;GO:0032466//negative regulation of cytokinesis","K09537//DnaJ homolog subfamily C member 17;K12182//hepatocyte growth factor-regulated tyrosine kinase substrate","NP_116239.3//abscission/NoCut checkpoint regulator isoform 3 [Homo sapiens];NP_001245349.1//abscission/NoCut checkpoint regulator isoform 2 [Homo sapiens];NP_001070736.1//abscission/NoCut checkpoint regulator isoform 1 [Homo sapiens]","4;1//3"]
[8804,2048,71.46,74.97,0.06917748822259,0.226451169875986,"*",0.1257432,"CREG1","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0035578//azurophil granule lumen;GO:0005667//transcription factor complex;GO:0005576//extracellular region","GO:0003714//transcription corepressor activity;GO:0048037//cofactor binding;GO:0008134//transcription factor binding","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0006355//regulation of transcription, DNA-templated;GO:0040008//regulation of growth;GO:0007275//multicellular organism development;GO:0043312//neutrophil degranulation","NA","NP_003842.1//protein CREG1 precursor [Homo sapiens]","2//1"]
[79177,1863,15.56,16.32,0.0687989969853036,0.636354724023211,"*",0.514892,"ZNF576","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","NP_077303.1//zinc finger protein 576 [Homo sapiens]","1//3;2//1"]
[50486,978,1.85,1.94,0.0685313816708155,0.929824506896552,"*",0.877786,"G0S2","GO:0005811//lipid droplet;GO:0016021//integral component of membrane;GO:0005739//mitochondrion","NA","GO:0097191//extrinsic apoptotic signaling pathway;GO:0019216//regulation of lipid metabolic process;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway","K10262//F-box and WD-40 domain protein 4;K13221//methylosome protein 50;K17776//metaxin","NP_056529.1//G0/G1 switch protein 2 [Homo sapiens]","3//A2MP1"]
[1939,2115,23.69,24.83,0.0678060629366095,0.536788108165057,"*",0.382748,"EIF2D","GO:0016604//nuclear body;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0003743//translation initiation factor activity;GO:0004872//receptor activity","GO:0006886//intracellular protein transport;GO:0075522//IRES-dependent viral translational initiation;GO:0032790//ribosome disassembly;GO:0001731//formation of translation preinitiation complex","K15027//translation initiation factor 2D","NP_008824.2//eukaryotic translation initiation factor 2D isoform 1 [Homo sapiens];NP_001188407.1//eukaryotic translation initiation factor 2D isoform 2 [Homo sapiens]","1//3;2//1"]
[143241,787,8.75,9.17,0.0676387168753633,0.828857123337029,"*",0.748846,"DYDC1","GO:0048188//Set1C/COMPASS complex;GO:0000781//chromosome, telomeric region","NA","GO:0051568//histone H3-K4 methylation;GO:0006348//chromatin silencing at telomere","K18626//trichohyalin;K03681//exosome complex component RRP40","NP_620167.1//DPY30 domain-containing protein 1 [Homo sapiens]","1//3;3//A2MP1"]
[4605,2756,88.84,93.07,0.0671068143620178,0.134728980570275,"*",0.06685,"MYBL2","GO:0031523//Myb complex;GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0003677//DNA binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0001135//transcription factor activity, RNA polymerase II transcription factor recruiting","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0043525//positive regulation of neuron apoptotic process;GO:1990830//cellular response to leukemia inhibitory factor;GO:0090307//mitotic spindle assembly;GO:0030154//cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0051726//regulation of cell cycle","K21769//myb-related protein B","NP_002457.1//myb-related protein B isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[23403,3084,13.6,14.24,0.0663424948286961,0.802782581662093,"*",0.714182,"FBXO46","NA","NA","NA","K10320//F-box protein 46","XP_010375767.1//PREDICTED: LOW QUALITY PROTEIN: F-box only protein 46 [Rhinopithecus roxellana]","1//3"]
[51497,2320,34.62,36.24,0.0659772306795965,0.425476837297812,"*",0.27994,"NELFCD","GO:0016020//membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0032021//NELF complex","GO:0003723//RNA binding","GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0045892//negative regulation of transcription, DNA-templated;GO:0050434//positive regulation of viral transcription;GO:0006366//transcription from RNA polymerase II promoter","K15181//negative elongation factor C/D","NP_945327.2//negative elongation factor C/D [Homo sapiens]","2//1"]
[84236,5052,3.89,4.07,0.0652586392800551,0.769527595666834,"*",0.671494,"RHBDD1","GO:0005783//endoplasmic reticulum;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005739//mitochondrion;GO:0005789//endoplasmic reticulum membrane;GO:0044322//endoplasmic reticulum quality control compartment","GO:0004252//serine-type endopeptidase activity;GO:0004175//endopeptidase activity","GO:0043687//post-translational protein modification;GO:0010954//positive regulation of protein processing;GO:0034620//cellular response to unfolded protein;GO:0043066//negative regulation of apoptotic process;GO:0006915//apoptotic process;GO:0034644//cellular response to UV;GO:0048515//spermatid differentiation;GO:0036503//ERAD pathway;GO:0045732//positive regulation of protein catabolic process;GO:0033619//membrane protein proteolysis;GO:0031293//membrane protein intracellular domain proteolysis;GO:1904211//membrane protein proteolysis involved in retrograde protein transport, ER to cytosol;GO:0051047//positive regulation of secretion","K09651//rhomboid domain-containing protein 1 [EC:3.4.21.-]","NP_115652.2//rhomboid-related protein 4 [Homo sapiens]","1//3;4;2//1"]
[91782,2807,24.35,25.46,0.0643106469316534,0.64869889354679,"*",0.492108,"CHMP7","GO:0005634//nucleus;GO:0000785//chromatin;GO:0005635//nuclear envelope;GO:0005829//cytosol;GO:0005622//intracellular;GO:0000815//ESCRT III complex","GO:0008565//protein transporter activity","GO:0016197//endosomal transport;GO:0006997//nucleus organization;GO:0071168//protein localization to chromatin;GO:0007034//vacuolar transport;GO:0045324//late endosome to vacuole transport;GO:0019058//viral life cycle;GO:0039702//viral budding via host ESCRT complex;GO:1904903//ESCRT III complex disassembly;GO:0036258//multivesicular body assembly;GO:0000920//cell separation after cytokinesis;GO:0007080//mitotic metaphase plate congression;GO:0010458//exit from mitosis;GO:0031468//nuclear envelope reassembly","K15053//charged multivesicular body protein 7","XP_017405228.1//PREDICTED: charged multivesicular body protein 7 [Cebus capucinus imitator];XP_021570945.1//charged multivesicular body protein 7 isoform X2 [Carlito syrichta]","4;1//3"]
[6352,1237,30.15,31.52,0.0641095326689292,0.677191502312533,"*",0.559126,"CCL5","GO:0005615//extracellular space;GO:0005622//intracellular;GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0004435//phosphatidylinositol phospholipase C activity;GO:0046817//chemokine receptor antagonist activity;GO:0043621//protein self-association;GO:0031726//CCR1 chemokine receptor binding;GO:0042803//protein homodimerization activity;GO:0031729//CCR4 chemokine receptor binding;GO:0004672//protein kinase activity;GO:0031730//CCR5 chemokine receptor binding;GO:0016004//phospholipase activator activity;GO:0008009//chemokine activity;GO:0030298//receptor signaling protein tyrosine kinase activator activity;GO:0042056//chemoattractant activity","GO:0010820//positive regulation of T cell chemotaxis;GO:0007159//leukocyte cell-cell adhesion;GO:0042102//positive regulation of T cell proliferation;GO:0043491//protein kinase B signaling;GO:0071356//cellular response to tumor necrosis factor;GO:0050796//regulation of insulin secretion;GO:0033634//positive regulation of cell-cell adhesion mediated by integrin;GO:0071346//cellular response to interferon-gamma;GO:0071347//cellular response to interleukin-1;GO:0043922//negative regulation by host of viral transcription;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0070234//positive regulation of T cell apoptotic process;GO:0048245//eosinophil chemotaxis;GO:0090026//positive regulation of monocyte chemotaxis;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0070098//chemokine-mediated signaling pathway;GO:0051262//protein tetramerization;GO:0031584//activation of phospholipase D activity;GO:0006816//calcium ion transport;GO:0034612//response to tumor necrosis factor;GO:1901214//regulation of neuron death;GO:0051928//positive regulation of calcium ion transport;GO:0043623//cellular protein complex assembly;GO:0010759//positive regulation of macrophage chemotaxis;GO:0045744//negative regulation of G-protein coupled receptor protein signaling pathway;GO:2000110//negative regulation of macrophage apoptotic process;GO:0009636//response to toxic substance;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0071407//cellular response to organic cyclic compound;GO:0045071//negative regulation of viral genome replication;GO:0070233//negative regulation of T cell apoptotic process;GO:0006874//cellular calcium ion homeostasis;GO:0014911//positive regulation of smooth muscle cell migration;GO:0007186//G-protein coupled receptor signaling pathway;GO:2000503//positive regulation of natural killer cell chemotaxis;GO:0000165//MAPK cascade;GO:0034112//positive regulation of homotypic cell-cell adhesion;GO:0042119//neutrophil activation;GO:0007267//cell-cell signaling;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0006954//inflammatory response;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0006955//immune response;GO:0031328//positive regulation of cellular biosynthetic process;GO:0009615//response to virus;GO:0050679//positive regulation of epithelial cell proliferation;GO:0006887//exocytosis","K12499//C-C motif chemokine 5","NP_001265665.1//C-C motif chemokine 5 isoform 2 precursor [Homo sapiens];XP_008009272.1//PREDICTED: C-C motif chemokine 5 [Chlorocebus sabaeus]","1//3;2//1"]
[64785,2235,14.4,15.05,0.0636946753173896,0.562238887369059,"*",0.406562,"GINS3","GO:0005634//nucleus;GO:0005654//nucleoplasm","NA","GO:0006260//DNA replication;GO:0006271//DNA strand elongation involved in DNA replication","K10734//GINS complex subunit 3","EPY84737.1//DNA replication complex GINS protein PSF3 isoform c [Camelus ferus];XP_008538624.1//PREDICTED: DNA replication complex GINS protein PSF3 [Equus przewalskii];NP_001119601.1//DNA replication complex GINS protein PSF3 isoform a [Homo sapiens]","1//3;3//A2MP1"]
[57794,2116,12.84,13.41,0.0626640347821708,0.670157625114017,"*",0.551934,"SUGP1","GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex","GO:0003723//RNA binding","GO:0006396//RNA processing;GO:0000398//mRNA splicing, via spliceosome","K13096//splicing factor 4","NP_757386.2//SURP and G-patch domain-containing protein 1 [Homo sapiens]","3//A2MP1"]
[6941,3219,11.27,11.77,0.0626268048662231,0.884211495648654,"*",0.8205,"TCF19","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003700//DNA binding transcription factor activity","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0006351//transcription, DNA-templated","K11446//histone demethylase JARID1 [EC:1.14.11.-]","NP_001070979.1//transcription factor 19 [Homo sapiens]","1//3;2//1"]
[79917,2654,1.16,1.21,0.0608822421470224,0.95002688672799,"*",0.905184,"MAGIX","NA","NA","NA","K06237//collagen, type IV, alpha;K05631//atrophin-1 interacting protein 3 (BAI1-associated protein 1);K22020//mucin-19;K05629//atrophin-1 interacting protein 1","NP_001093152.2//PDZ domain-containing protein MAGIX isoform d [Homo sapiens];NP_001093151.2//PDZ domain-containing protein MAGIX isoform c [Homo sapiens];NP_079135.3//PDZ domain-containing protein MAGIX isoform a [Homo sapiens]","3//A2MP1;2//1"]
[64285,3091,10.07,10.5,0.0603256445467004,0.650532799507995,"*",0.529744,"RHBDF1","GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0000139//Golgi membrane","GO:0004252//serine-type endopeptidase activity;GO:0019838//growth factor binding","GO:0016477//cell migration;GO:0006508//proteolysis;GO:0050709//negative regulation of protein secretion;GO:0008283//cell proliferation;GO:0042058//regulation of epidermal growth factor receptor signaling pathway;GO:0050708//regulation of protein secretion;GO:0015031//protein transport;GO:0061136//regulation of proteasomal protein catabolic process","K21125//mucin-5AC","NP_071895.3//inactive rhomboid protein 1 [Homo sapiens]","3//A2MP1"]
[149840,1418,9.46,9.86,0.0597474630385161,0.638666097463948,"*",0.482418,"C20orf196","NA","NA","NA","K19991//chromogranin-B","XP_004061828.1//PREDICTED: uncharacterized protein C20orf196 isoform X1 [Gorilla gorilla gorilla];XP_012365710.1//PREDICTED: uncharacterized protein C20orf196 homolog isoform X3 [Nomascus leucogenys];XP_011527479.1//PREDICTED: uncharacterized protein C20orf196 isoform X1 [Homo sapiens];XP_011527482.1//PREDICTED: uncharacterized protein C20orf196 isoform X6 [Homo sapiens]","1//3;3//A2MP1"]
[85463,8807,0.96,1,0.0588936890535686,0.810731637814009,"*",0.725314,"ZC3H12C","NA","GO:0046872//metal ion binding","NA","K18668//ribonuclease ZC3H12 [EC:3.1.-.-]","XP_009422404.1//PREDICTED: probable ribonuclease ZC3H12C isoform X3 [Pan troglodytes]","1//3"]
[9138,3236,44.95,46.81,0.0584956493101446,0.367448731161102,"*",0.228028,"ARHGEF1","GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity","GO:0007266//Rho protein signal transduction;GO:0043065//positive regulation of apoptotic process;GO:0008283//cell proliferation;GO:0050771//negative regulation of axonogenesis;GO:0035023//regulation of Rho protein signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction","K12330//Rho guanine nucleotide exchange factor 1","NP_945353.1//rho guanine nucleotide exchange factor 1 isoform 1 [Homo sapiens];XP_008963082.1//PREDICTED: rho guanine nucleotide exchange factor 1 isoform X5 [Pan paniscus]","1//3;3//A2MP1"]
[51634,1861,12.66,13.18,0.0580729655797105,0.720970551616499,"*",0.607278,"RBMX2","GO:0005686//U2 snRNP;GO:0071011//precatalytic spliceosome;GO:0070274//RES complex;GO:0071013//catalytic step 2 spliceosome","GO:0003723//RNA binding","GO:0006406//mRNA export from nucleus;GO:0000398//mRNA splicing, via spliceosome","K13107//RNA-binding motif protein, X-linked 2","NP_057108.2//RNA-binding motif protein, X-linked 2 [Homo sapiens]","3//A2MP1"]
[7059,3251,3.92,4.08,0.0577154978562874,0.650100422042567,"*",0.493334,"THBS3","GO:0005576//extracellular region;GO:0048471//perinuclear region of cytoplasm","GO:0005509//calcium ion binding;GO:0008201//heparin binding","GO:0007160//cell-matrix adhesion;GO:0007155//cell adhesion;GO:0003417//growth plate cartilage development;GO:0060346//bone trabecula formation;GO:0043931//ossification involved in bone maturation","K04659//thrombospondin 2/3/4/5","NP_001239537.1//thrombospondin-3 isoform 3 precursor [Homo sapiens];NP_001239536.1//thrombospondin-3 isoform 2 precursor [Homo sapiens];NP_009043.1//thrombospondin-3 isoform 1 precursor [Homo sapiens]","4;1//3"]
[56945,1155,29.53,30.73,0.0574664104590079,0.661430614561028,"*",0.541434,"MRPS22","GO:0005840//ribosome;GO:0005761//mitochondrial ribosome;GO:0005763//mitochondrial small ribosomal subunit;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0003735//structural constituent of ribosome","GO:0070126//mitochondrial translational termination;GO:0070125//mitochondrial translational elongation","K17401//small subunit ribosomal protein S22","NP_064576.1//28S ribosomal protein S22, mitochondrial [Homo sapiens]","2//1"]
[4795,1473,8.93,9.29,0.05701842126143,0.749347251049052,"*",0.648396,"NFKBIL1","GO:0005634//nucleus;GO:0005829//cytosol","NA","GO:0042994//cytoplasmic sequestering of transcription factor;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0031665//negative regulation of lipopolysaccharide-mediated signaling pathway;GO:0071222//cellular response to lipopolysaccharide;GO:0032720//negative regulation of tumor necrosis factor production;GO:0034122//negative regulation of toll-like receptor signaling pathway;GO:0032088//negative regulation of NF-kappaB transcription factor activity","K09256//NF-kappa-B inhibitor-like protein 1","XP_011855843.1//PREDICTED: NF-kappa-B inhibitor-like protein 1 isoform X1 [Mandrillus leucophaeus];XP_011855844.1//PREDICTED: NF-kappa-B inhibitor-like protein 1 isoform X2 [Mandrillus leucophaeus];NP_001138433.1//NF-kappa-B inhibitor-like protein 1 isoform 2 [Homo sapiens];NP_004998.3//NF-kappa-B inhibitor-like protein 1 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[1759,3890,127.86,132.98,0.0566442838359529,0.0134688010975184,"*",4.82462E-3,"DNM1","GO:0070062//extracellular exosome;GO:0001917//photoreceptor inner segment;GO:0005874//microtubule;GO:0008021//synaptic vesicle;GO:0043209//myelin sheath;GO:0043196//varicosity;GO:0030117//membrane coat;GO:0005794//Golgi apparatus;GO:0031966//mitochondrial membrane;GO:0045202//synapse;GO:0005886//plasma membrane","GO:0003723//RNA binding;GO:0042802//identical protein binding;GO:0008017//microtubule binding;GO:0019901//protein kinase binding;GO:0046983//protein dimerization activity;GO:0003924//GTPase activity;GO:0050998//nitric-oxide synthase binding;GO:0031749//D2 dopamine receptor binding;GO:0008022//protein C-terminus binding;GO:0005525//GTP binding;GO:0032403//protein complex binding","GO:0072583//clathrin-dependent endocytosis;GO:0048013//ephrin receptor signaling pathway;GO:0008344//adult locomotory behavior;GO:0051262//protein tetramerization;GO:0016185//synaptic vesicle budding from presynaptic endocytic zone membrane;GO:0003374//dynamin family protein polymerization involved in mitochondrial fission;GO:0051932//synaptic transmission, GABAergic;GO:0061025//membrane fusion;GO:1901998//toxin transport;GO:0007605//sensory perception of sound;GO:0006898//receptor-mediated endocytosis;GO:0006897//endocytosis;GO:0007032//endosome organization;GO:0002031//G-protein coupled receptor internalization;GO:0000266//mitochondrial fission;GO:1903423//positive regulation of synaptic vesicle recycling","K01528//dynamin GTPase [EC:3.6.5.5]","NP_004399.2//dynamin-1 isoform 1 [Homo sapiens];NP_001005336.1//dynamin-1 isoform 2 [Homo sapiens];BAD90284.1//mKIAA4093 protein, partial [Mus musculus];NP_001275668.1//dynamin-1 isoform 4 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[55324,2570,15.03,15.63,0.0564727690833001,0.665608903422517,"*",0.546646,"ABCF3","NA","NA","NA","K06158//ATP-binding cassette, subfamily F, member 3","NP_001338228.1//ATP-binding cassette sub-family F member 3 isoform 3 [Homo sapiens];XP_007195384.1//PREDICTED: ATP-binding cassette sub-family F member 3 [Balaenoptera acutorostrata scammoni]","1//3;2//1"]
[51434,2728,27.54,28.63,0.0559991108643888,0.358839623931624,"*",0.220776,"ANAPC7","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005680//anaphase-promoting complex","GO:0019903//protein phosphatase binding","GO:0070979//protein K11-linked ubiquitination;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0051301//cell division;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle","K03354//anaphase-promoting complex subunit 7","NP_057322.2//anaphase-promoting complex subunit 7 isoform a [Homo sapiens];NP_001131136.1//anaphase-promoting complex subunit 7 isoform b [Homo sapiens]","1//3;2//1"]
[8216,4332,10.94,11.37,0.0556195160996913,0.627246443407234,"*",0.471122,"LZTR1","GO:0005794//Golgi apparatus","GO:0003700//DNA binding transcription factor activity","GO:0009653//anatomical structure morphogenesis","K14966//host cell factor;K20285//Rab9 effector protein with kelch motifs","NP_006758.2//leucine-zipper-like transcriptional regulator 1 [Homo sapiens]","3//A2MP1"]
[202243,3511,4.64,4.82,0.0549083411023897,0.805215784384004,"*",0.717254,"CCDC125","GO:0005737//cytoplasm","NA","GO:0090630//activation of GTPase activity;GO:2000146//negative regulation of cell motility;GO:2000145//regulation of cell motility;GO:0035024//negative regulation of Rho protein signal transduction","K05765//cofilin;K17985//activating molecule in BECN1-regulated autophagy protein 1;K06662//cell cycle checkpoint protein","NP_001284625.1//coiled-coil domain-containing protein 125 isoform 2 [Homo sapiens];XP_005248516.1//PREDICTED: coiled-coil domain-containing protein 125 isoform X2 [Homo sapiens];EAW51298.1//Kenae, isoform CRA_a, partial [Homo sapiens]","4;1//3"]
[1892,1350,74.71,77.58,0.0543834139145738,0.465929962333826,"*",0.315948,"ECHS1","GO:0005759//mitochondrial matrix;GO:0070062//extracellular exosome;GO:0005739//mitochondrion","GO:0003824//catalytic activity;GO:0004300//enoyl-CoA hydratase activity","GO:0006635//fatty acid beta-oxidation;GO:0008152//metabolic process","K07511//enoyl-CoA hydratase [EC:4.2.1.17]","NP_004083.3//enoyl-CoA hydratase, mitochondrial [Homo sapiens]","3//A2MP1"]
[93323,1468,8.63,8.96,0.054138172878649,0.81143705697446,"*",0.723964,"HAUS8","GO:0000922//spindle pole;GO:0005874//microtubule;GO:0070652//HAUS complex;GO:0005829//cytosol;GO:0005813//centrosome","NA","GO:0010389//regulation of G2/M transition of mitotic cell cycle;GO:0097711//ciliary basal body-plasma membrane docking;GO:0007098//centrosome cycle;GO:0051225//spindle assembly;GO:0051301//cell division;GO:0000086//G2/M transition of mitotic cell cycle","K16591//HAUS augmin-like complex subunit 8","NP_219485.1//HAUS augmin-like complex subunit 8 isoform a [Homo sapiens];NP_001011699.1//HAUS augmin-like complex subunit 8 isoform b [Homo sapiens]","1//3"]
[5641,2185,33.22,34.48,0.0537077011267218,0.560776936325045,"*",0.405224,"LGMN","GO:0070062//extracellular exosome;GO:0005770//late endosome;GO:0043202//lysosomal lumen;GO:0005764//lysosome;GO:0045177//apical part of cell;GO:0036021//endolysosome lumen","GO:0008233//peptidase activity;GO:0004197//cysteine-type endopeptidase activity","GO:0032801//receptor catabolic process;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0043524//negative regulation of neuron apoptotic process;GO:0002224//toll-like receptor signaling pathway;GO:1901185//negative regulation of ERBB signaling pathway;GO:0003014//renal system process;GO:0006508//proteolysis;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0010447//response to acidic pH;GO:0006624//vacuolar protein processing;GO:0040015//negative regulation of multicellular organism growth;GO:0042359//vitamin D metabolic process","K01369//legumain [EC:3.4.22.34]","NP_005597.3//legumain preproprotein [Homo sapiens]","6;2//1"]
[57509,4085,57.81,59.99,0.0534029591532266,0.000550504539585297,"*",0.000146259,"MTUS1","GO:0005815//microtubule organizing center;GO:0005615//extracellular space;GO:0005730//nucleolus;GO:0005874//microtubule;GO:0015630//microtubule cytoskeleton;GO:0005794//Golgi apparatus;GO:0005819//spindle;GO:0005739//mitochondrion;GO:0005886//plasma membrane","NA","NA","K10352//myosin heavy chain;K21954//FYVE and coiled-coil domain-containing protein 1;K20283//golgin subfamily A member 4;K18626//trichohyalin;K20478//golgin subfamily B member 1","NP_001001924.1//microtubule-associated tumor suppressor 1 isoform 1 [Homo sapiens];NP_001001925.1//microtubule-associated tumor suppressor 1 isoform 2 [Homo sapiens];NP_001317399.1//microtubule-associated tumor suppressor 1 isoform 7 [Homo sapiens];NP_001001931.1//microtubule-associated tumor suppressor 1 isoform 4 [Homo sapiens];NP_065800.1//microtubule-associated tumor suppressor 1 isoform 5 [Homo sapiens]","1//3;4;2//1"]
[50813,2003,44.24,45.89,0.0528284211775653,0.695511881033055,"*",0.578258,"COPS7A","NA","NA","NA","K12180//COP9 signalosome complex subunit 7","XP_019609974.1//PREDICTED: COP9 signalosome complex subunit 7a isoform X1 [Rhinolophus sinicus];XP_011364134.1//PREDICTED: COP9 signalosome complex subunit 7a isoform X1 [Pteropus vampyrus]","1//3;3//A2MP1;2//1"]
[2671,2447,17.54,18.19,0.0524967952067534,0.645437708651105,"*",0.524504,"GFER","GO:0005829//cytosol;GO:0005758//mitochondrial intermembrane space;GO:0005576//extracellular region;GO:0005739//mitochondrion","GO:0015035//protein disulfide oxidoreductase activity;GO:0008083//growth factor activity;GO:0016971//flavin-linked sulfhydryl oxidase activity;GO:0050660//flavin adenine dinucleotide binding;GO:0016972//thiol oxidase activity","GO:0001889//liver development","K17783//mitochondrial FAD-linked sulfhydryl oxidase [EC:1.8.3.2]","EAW85579.1//growth factor, augmenter of liver regeneration (ERV1 homolog, S. cerevisiae), isoform CRA_b, partial [Homo sapiens]","2//1"]
[117177,9287,1.92,1.99,0.0516621198224926,0.813493545454546,"*",0.730484,"RAB3IP","GO:0005856//cytoskeleton;GO:0036064//ciliary basal body;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005813//centrosome;GO:0030027//lamellipodium","GO:0042802//identical protein binding;GO:0017112//Rab guanyl-nucleotide exchange factor activity","GO:0006612//protein targeting to membrane;GO:0060271//cilium assembly;GO:0097711//ciliary basal body-plasma membrane docking;GO:0033365//protein localization to organelle;GO:0061024//membrane organization;GO:0006893//Golgi to plasma membrane transport","K16779//Rab-3A-interacting protein","NP_783322.1//rab-3A-interacting protein isoform alpha 2 [Homo sapiens];XP_006719290.3//PREDICTED: rab-3A-interacting protein isoform X3 [Homo sapiens];XP_018894075.1//PREDICTED: rab-3A-interacting protein isoform X1 [Gorilla gorilla gorilla];NP_783324.1//rab-3A-interacting protein isoform beta 2 [Homo sapiens]","1//3;4;3//A2MP1"]
[54978,3912,41.99,43.51,0.0513012287055122,0.362153006192265,"*",0.223336,"SLC35F6","GO:0005765//lysosomal membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005739//mitochondrion","NA","GO:1901029//negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway;GO:0008284//positive regulation of cell proliferation","K15696//RING finger protein 113B;K00772//5'-methylthioadenosine phosphorylase [EC:2.4.2.28]","XP_012643642.1//solute carrier family 35 member F6 [Microcebus murinus]","3//A2MP1"]
[26088,3184,15.39,15.94,0.0506583976622613,0.633083650756694,"*",0.476616,"GGA1","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0010008//endosome membrane;GO:0005654//nucleoplasm;GO:0030131//clathrin adaptor complex;GO:0031901//early endosome membrane;GO:0005794//Golgi apparatus;GO:0043234//protein complex","GO:0030306//ADP-ribosylation factor binding;GO:0046982//protein heterodimerization activity","GO:0006886//intracellular protein transport;GO:0044267//cellular protein metabolic process;GO:1901998//toxin transport;GO:0045732//positive regulation of protein catabolic process;GO:0016192//vesicle-mediated transport;GO:0061024//membrane organization","K12404//ADP-ribosylation factor-binding protein GGA","NP_037497.1//ADP-ribosylation factor-binding protein GGA1 isoform 1 [Homo sapiens];NP_001166158.1//ADP-ribosylation factor-binding protein GGA1 isoform 4 [Homo sapiens];NP_001001560.1//ADP-ribosylation factor-binding protein GGA1 isoform 2 [Homo sapiens]","1//3;4;2//1"]
[10551,996,23.4,24.23,0.0502858749805797,0.759892847262248,"*",0.66028,"AGR2","GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005739//mitochondrion","GO:0005154//epidermal growth factor receptor binding;GO:0002162//dystroglycan binding;GO:0042803//protein homodimerization activity","GO:1903899//positive regulation of PERK-mediated unfolded protein response;GO:0030154//cell differentiation;GO:0048639//positive regulation of developmental growth;GO:0010628//positive regulation of gene expression;GO:0048546//digestive tract morphogenesis;GO:0060480//lung goblet cell differentiation;GO:0070254//mucus secretion;GO:1903078//positive regulation of protein localization to plasma membrane;GO:0060548//negative regulation of cell death;GO:0045742//positive regulation of epidermal growth factor receptor signaling pathway;GO:0010811//positive regulation of cell-substrate adhesion;GO:1903896//positive regulation of IRE1-mediated unfolded protein response","K20356//anterior gradient protein 2","AAY84773.1//AGR2 [Homo sapiens]","3//A2MP1"]
[7307,978,64.35,66.6,0.0495820288505604,0.639599009344351,"*",0.518478,"U2AF1","GO:0005654//nucleoplasm;GO:0089701//U2AF;GO:0005681//spliceosomal complex;GO:0016607//nuclear speck;GO:0015030//Cajal body;GO:0071013//catalytic step 2 spliceosome","GO:0050733//RS domain binding;GO:0003723//RNA binding;GO:0046872//metal ion binding;GO:0030628//pre-mRNA 3'-splice site binding","GO:0006397//mRNA processing;GO:0006406//mRNA export from nucleus;GO:0000398//mRNA splicing, via spliceosome;GO:1903955//positive regulation of protein targeting to mitochondrion;GO:0006369//termination of RNA polymerase II transcription;GO:1903146//regulation of autophagy of mitochondrion;GO:0031124//mRNA 3'-end processing;GO:0006405//RNA export from nucleus;GO:0008380//RNA splicing","K12836//splicing factor U2AF 35 kDa subunit","NP_006749.1//splicing factor U2AF 35 kDa subunit isoform a [Homo sapiens];XP_004092375.1//PREDICTED: splicing factor U2AF 35 kDa subunit isoform X2 [Nomascus leucogenys];NP_001020374.1//splicing factor U2AF 35 kDa subunit isoform b [Homo sapiens]","1//3;2//1"]
[124454,3965,14.77,15.28,0.0489747172709595,0.63596330040674,"*",0.47962,"EARS2","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0050561//glutamate-tRNA(Gln) ligase activity;GO:0005524//ATP binding;GO:0008270//zinc ion binding;GO:0000049//tRNA binding;GO:0004818//glutamate-tRNA ligase activity","GO:0070127//tRNA aminoacylation for mitochondrial protein translation;GO:0006424//glutamyl-tRNA aminoacylation","K01885//glutamyl-tRNA synthetase [EC:6.1.1.17]","NP_001295140.1//probable glutamate--tRNA ligase, mitochondrial isoform 2 [Homo sapiens];NP_001077083.1//probable glutamate--tRNA ligase, mitochondrial isoform 1 [Homo sapiens]","1//3"]
[8607,1906,50.97,52.72,0.0487020171026752,0.765045258268622,"*",0.666098,"RUVBL1","GO:0000812//Swr1 complex;GO:0035267//NuA4 histone acetyltransferase complex;GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005815//microtubule organizing center;GO:0031011//Ino80 complex;GO:0016363//nuclear matrix;GO:0071339//MLL1 complex;GO:0043234//protein complex;GO:0005829//cytosol;GO:0030529//intracellular ribonucleoprotein complex;GO:0097255//R2TP complex","GO:0005524//ATP binding;GO:0051117//ATPase binding;GO:0045296//cadherin binding;GO:0004003//ATP-dependent DNA helicase activity;GO:0043531//ADP binding;GO:0043140//ATP-dependent 3'-5' DNA helicase activity;GO:0043141//ATP-dependent 5'-3' DNA helicase activity;GO:0003678//DNA helicase activity;GO:0016887//ATPase activity;GO:0001094//TFIID-class transcription factor binding","GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0040008//regulation of growth;GO:1903955//positive regulation of protein targeting to mitochondrion;GO:0043968//histone H2A acetylation;GO:0007283//spermatogenesis;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0043967//histone H4 acetylation;GO:0016579//protein deubiquitination;GO:0006281//DNA repair;GO:0016573//histone acetylation;GO:0006351//transcription, DNA-templated;GO:1903146//regulation of autophagy of mitochondrion;GO:2000269//regulation of fibroblast apoptotic process;GO:0000492//box C/D snoRNP assembly;GO:1904837//beta-catenin-TCF complex assembly;GO:1904874//positive regulation of telomerase RNA localization to Cajal body;GO:0051301//cell division;GO:0034080//CENP-A containing nucleosome assembly;GO:0010756//positive regulation of plasminogen activation;GO:0006310//DNA recombination;GO:0007049//cell cycle","K04499//RuvB-like protein 1 (pontin 52)","OBS67033.1//hypothetical protein A6R68_04429, partial [Neotoma lepida];XP_011511551.1//PREDICTED: ruvB-like 1 isoform X5 [Homo sapiens];XP_022377181.1//ruvB-like 1 isoform X2 [Enhydra lutris kenyoni]","1//3;2//1"]
[6839,2752,25.24,26.1,0.048337896474698,0.609247523028818,"*",0.45131,"SUV39H1","GO:0005652//nuclear lamina;GO:0033553//rDNA heterochromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0000775//chromosome, centromeric region;GO:0000794//condensed nuclear chromosome;GO:0005677//chromatin silencing complex;GO:0000792//heterochromatin","GO:0008757//S-adenosylmethionine-dependent methyltransferase activity;GO:0046974//histone methyltransferase activity (H3-K9 specific);GO:0047485//protein N-terminus binding;GO:0003682//chromatin binding;GO:0008270//zinc ion binding;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0042054//histone methyltransferase activity;GO:0018024//histone-lysine N-methyltransferase activity","GO:0045892//negative regulation of transcription, DNA-templated;GO:0071456//cellular response to hypoxia;GO:0042754//negative regulation of circadian rhythm;GO:0036124//histone H3-K9 trimethylation;GO:0030154//cell differentiation;GO:0006351//transcription, DNA-templated;GO:0016032//viral process;GO:0006364//rRNA processing;GO:0048511//rhythmic process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006325//chromatin organization;GO:0000183//chromatin silencing at rDNA;GO:0036123//histone H3-K9 dimethylation;GO:0007049//cell cycle;GO:0006974//cellular response to DNA damage stimulus","K11419//histone-lysine N-methyltransferase SUV39H [EC:2.1.1.43]","XP_012327085.1//histone-lysine N-methyltransferase SUV39H1 isoform X2 [Aotus nancymaae];NP_001125697.1//histone-lysine N-methyltransferase SUV39H1 [Pongo abelii]","1//3;3//A2MP1"]
[2189,2649,29.49,30.48,0.0476370804315853,0.590388915921288,"*",0.433866,"FANCG","GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0043240//Fanconi anaemia nuclear complex;GO:0005886//plasma membrane","GO:0003684//damaged DNA binding;GO:0004871//signal transducer activity","GO:0006281//DNA repair;GO:0007286//spermatid development;GO:0001541//ovarian follicle development;GO:0007005//mitochondrion organization;GO:0000075//cell cycle checkpoint;GO:0000160//phosphorelay signal transduction system;GO:0009314//response to radiation;GO:0036297//interstrand cross-link repair;GO:0006974//cellular response to DNA damage stimulus","K10894//fanconi anemia group G protein","NP_004620.1//Fanconi anemia group G protein [Homo sapiens]","1//3"]
[388969,4283,11.12,11.49,0.047222009922606,0.664440329285987,"*",0.544688,"C2orf68","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein;K12581//CCR4-NOT transcription complex subunit 7/8;K12900//FUS-interacting serine-arginine-rich protein 1;K01064//wingless-type MMTV integration site family, member 9","NP_001013671.2//UPF0561 protein C2orf68 [Homo sapiens]","3//A2MP1"]
[388886,1240,7.96,8.22,0.0463699631380342,0.858637667007987,"*",0.787416,"LRRC75B","NA","NA","NA","K19719//collagen, type II, alpha;K06236//collagen, type I, alpha;K17446//insulin receptor substrate 4","NP_997527.2//leucine-rich repeat-containing protein 75B [Homo sapiens]","2//1"]
[51247,1498,40.16,41.45,0.0456128324323409,0.63366748413067,"*",0.51244,"PAIP2","GO:0005737//cytoplasm","GO:0003729//mRNA binding;GO:0030371//translation repressor activity","GO:1900271//regulation of long-term synaptic potentiation;GO:0045947//negative regulation of translational initiation;GO:0007613//memory;GO:0007283//spermatogenesis","NA","NP_057564.3//polyadenylate-binding protein-interacting protein 2 [Homo sapiens]","4;2//1"]
[55256,1863,41.69,43.02,0.0453061526146722,1.01831185933504,"*",0.99702,"ADI1","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0010309//acireductone dioxygenase [iron(II)-requiring] activity;GO:0016491//oxidoreductase activity","GO:0019509//L-methionine salvage from methylthioadenosine","K08967//1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase [EC:1.13.11.53 1.13.11.54]","XP_018877019.1//PREDICTED: 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase isoform X1 [Gorilla gorilla gorilla];NP_001293006.1//1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[85416,4657,3.18,3.28,0.0446690493337283,0.824904364973633,"*",0.744242,"ZIC5","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003676//nucleic acid binding","GO:0007399//nervous system development;GO:0030154//cell differentiation","K09226//zinc finger protein ZIC 5","NP_149123.2//zinc finger protein ZIC 5 [Homo sapiens]",4]
[56052,3859,30.01,30.94,0.0440298778507472,0.653505450832886,"*",0.532942,"ALG1","GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0004578//chitobiosyldiphosphodolichol beta-mannosyltransferase activity;GO:0000030//mannosyltransferase activity","GO:0006486//protein glycosylation;GO:0006488//dolichol-linked oligosaccharide biosynthetic process","K03842//beta-1,4-mannosyltransferase [EC:2.4.1.142]","NP_061982.3//chitobiosyldiphosphodolichol beta-mannosyltransferase isoform 1 [Homo sapiens]","1//3;4"]
[954,2156,0.65,0.67,0.0437213774293181,0.918112057253179,"*",0.863338,"ENTPD2","GO:0070062//extracellular exosome;GO:0005605//basal lamina;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane","GO:0005524//ATP binding;GO:0017111//nucleoside-triphosphatase activity;GO:0017110//nucleoside-diphosphatase activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0009181//purine ribonucleoside diphosphate catabolic process;GO:0034656//nucleobase-containing small molecule catabolic process;GO:0030168//platelet activation","K01509//adenosinetriphosphatase [EC:3.6.1.3]","NP_982293.1//ectonucleoside triphosphate diphosphohydrolase 2 isoform 1 [Homo sapiens];NP_001237.1//ectonucleoside triphosphate diphosphohydrolase 2 isoform 2 [Homo sapiens]","3//A2MP1;2//1"]
[8813,1121,34.23,35.27,0.0431802834164143,0.718693429484797,"*",0.60518,"DPM1","GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0033185//dolichol-phosphate-mannose synthase complex;GO:0005789//endoplasmic reticulum membrane","GO:0016757//transferase activity, transferring glycosyl groups;GO:0004582//dolichyl-phosphate beta-D-mannosyltransferase activity;GO:0043178//alcohol binding;GO:0005537//mannose binding;GO:0004169//dolichyl-phosphate-mannose-protein mannosyltransferase activity","GO:0006506//GPI anchor biosynthetic process;GO:0035269//protein O-linked mannosylation;GO:0018279//protein N-linked glycosylation via asparagine;GO:0019348//dolichol metabolic process;GO:0019673//GDP-mannose metabolic process;GO:0035268//protein mannosylation","K00721//dolichol-phosphate mannosyltransferase [EC:2.4.1.83]","NP_001303964.1//dolichol-phosphate mannosyltransferase subunit 1 isoform 2 [Homo sapiens];NP_001303963.1//dolichol-phosphate mannosyltransferase subunit 1 isoform 1 [Homo sapiens];NP_001303965.1//dolichol-phosphate mannosyltransferase subunit 1 isoform 4 [Homo sapiens];XP_018872616.1//PREDICTED: dolichol-phosphate mannosyltransferase subunit 1 [Gorilla gorilla gorilla]","1//3;2//1"]
[91942,719,34.6,35.65,0.0431300388071634,0.787099402604757,"*",0.69614,"NDUFAF2","GO:0016020//membrane;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0009055//electron transfer activity;GO:0008137//NADH dehydrogenase (ubiquinone) activity","GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0061179//negative regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0022904//respiratory electron transport chain;GO:0072593//reactive oxygen species metabolic process;GO:0045333//cellular respiration","K18160//NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2","NP_777549.1//NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 [Homo sapiens]",4]
[124995,1852,63.78,65.7,0.042789272957431,0.544714655488604,"*",0.39048,"MRPL10","GO:0005840//ribosome;GO:0005654//nucleoplasm;GO:0005762//mitochondrial large ribosomal subunit;GO:0030529//intracellular ribonucleoprotein complex;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome","GO:0042254//ribosome biogenesis;GO:0032543//mitochondrial translation;GO:0006412//translation;GO:0070126//mitochondrial translational termination;GO:0070125//mitochondrial translational elongation","K02864//large subunit ribosomal protein L10","NP_683685.1//39S ribosomal protein L10, mitochondrial isoform b [Homo sapiens];XP_003826816.1//PREDICTED: 39S ribosomal protein L10, mitochondrial-like [Pan paniscus]","3//A2MP1;2//1"]
[25851,5752,4.41,4.54,0.0419136417333943,0.795491229228382,"*",0.706052,"TECPR1","GO:0005765//lysosomal membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005654//nucleoplasm;GO:0031410//cytoplasmic vesicle;GO:0016021//integral component of membrane;GO:0000421//autophagosome membrane","GO:0032266//phosphatidylinositol-3-phosphate binding","GO:0097352//autophagosome maturation;GO:0006914//autophagy","K17988//tectonin beta-propeller repeat-containing protein 1","NP_056210.1//tectonin beta-propeller repeat-containing protein 1 [Homo sapiens]","2//1"]
[55501,2131,9.85,10.14,0.0418620226596019,0.80037993495706,"*",0.711794,"CHST12","GO:0016020//membrane;GO:0030173//integral component of Golgi membrane;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0047756//chondroitin 4-sulfotransferase activity;GO:0050656//3'-phosphoadenosine 5'-phosphosulfate binding;GO:0008146//sulfotransferase activity","GO:0016051//carbohydrate biosynthetic process;GO:0030208//dermatan sulfate biosynthetic process;GO:0030206//chondroitin sulfate biosynthetic process","K04742//chondroitin 4-sulfotransferase 12 [EC:2.8.2.5]","XP_021791295.1//carbohydrate sulfotransferase 12 isoform X1 [Papio anubis];XP_008017044.1//PREDICTED: carbohydrate sulfotransferase 12 isoform X2 [Chlorocebus sabaeus]","4;1//3"]
[51575,3205,10.03,10.32,0.0411213648110735,0.755430117647059,"*",0.65522,"ESF1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005615//extracellular space;GO:0005730//nucleolus","GO:0003723//RNA binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K22023//mucin-6","NP_057733.2//ESF1 homolog [Homo sapiens]","1//3;3//A2MP1"]
[84826,2824,5.98,6.15,0.0404409260284973,0.834130953247828,"*",0.757266,"SFT2D3","GO:0016020//membrane;GO:0016021//integral component of membrane","NA","GO:0015031//protein transport;GO:0016192//vesicle-mediated transport","K22022//mucin-21","XP_002812413.1//PREDICTED: vesicle transport protein SFT2C [Pongo abelii]","3//A2MP1"]
[10809,1988,8.52,8.76,0.0400774393753351,0.833664123853527,"*",0.75679,"STARD10","NA","NA","NA","K20632//deleted in liver cancer protein","XP_008563271.1//PREDICTED: PCTP-like protein [Galeopterus variegatus]","2//1"]
[79073,2412,70.46,72.37,0.0385872967748899,0.49735030186628,"*",0.343668,"TMEM109","GO:0070062//extracellular exosome;GO:0005622//intracellular;GO:0016021//integral component of membrane;GO:0033017//sarcoplasmic reticulum membrane;GO:0005640//nuclear outer membrane","GO:0005244//voltage-gated ion channel activity","GO:0060548//negative regulation of cell death;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0071480//cellular response to gamma radiation","K10599//pre-mRNA-processing factor 19 [EC:2.3.2.27];K17599//transmembrane protein 132","NP_076997.1//transmembrane protein 109 precursor [Homo sapiens]","2//1"]
[113230,1329,2.26,2.32,0.0378020327123845,0.947314593649333,"*",0.902066,"MISP3","NA","NA","NA","K16628//collagen, type VII, alpha;K16519//A-kinase anchor protein 2","NP_001278220.1//uncharacterized protein MISP3 [Homo sapiens]","1//3"]
[55298,2623,13.6,13.96,0.0376922900719507,0.767105193969849,"*",0.668948,"RNF121","GO:0016021//integral component of membrane","NA","NA","K15698//RING finger protein 121","XP_015481775.1//PREDICTED: RING finger protein 121 isoform X4 [Parus major];XP_003254826.1//PREDICTED: RING finger protein 121 isoform X1 [Nomascus leucogenys]","4;1//3"]
[9093,2678,40.45,41.49,0.0366239545543105,0.700079370045703,"*",0.584948,"DNAJA3","GO:0005759//mitochondrial matrix;GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0042645//mitochondrial nucleoid;GO:0031594//neuromuscular junction;GO:0030054//cell junction;GO:0005737//cytoplasm;GO:0019897//extrinsic component of plasma membrane;GO:0005884//actin filament;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0045211//postsynaptic membrane","GO:0005524//ATP binding;GO:0031072//heat shock protein binding;GO:0019901//protein kinase binding;GO:0030695//GTPase regulator activity;GO:0046872//metal ion binding;GO:0051059//NF-kappaB binding;GO:0051082//unfolded protein binding;GO:0030544//Hsp70 protein binding;GO:0005133//interferon-gamma receptor binding;GO:0008134//transcription factor binding","GO:0007528//neuromuscular junction development;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043069//negative regulation of programmed cell death;GO:0042102//positive regulation of T cell proliferation;GO:0033077//T cell differentiation in thymus;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0043065//positive regulation of apoptotic process;GO:0007264//small GTPase mediated signal transduction;GO:0034341//response to interferon-gamma;GO:0006924//activation-induced cell death of T cells;GO:0071340//skeletal muscle acetylcholine-gated channel clustering;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0008285//negative regulation of cell proliferation;GO:0006457//protein folding;GO:0007569//cell aging;GO:0031398//positive regulation of protein ubiquitination;GO:0060336//negative regulation of interferon-gamma-mediated signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0009408//response to heat;GO:0007005//mitochondrion organization;GO:0006264//mitochondrial DNA replication;GO:0006469//negative regulation of protein kinase activity;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0050821//protein stabilization","K09504//DnaJ homolog subfamily A member 3","NP_001128582.1//dnaJ homolog subfamily A member 3, mitochondrial isoform 2 [Homo sapiens];NP_001273445.1//dnaJ homolog subfamily A member 3, mitochondrial isoform 3 [Homo sapiens];NP_005138.3//dnaJ homolog subfamily A member 3, mitochondrial isoform 1 [Homo sapiens]","1//3;2//1;5"]
[9092,3601,18.96,19.44,0.0360692547075217,0.687874720833648,"*",0.570272,"SART1","GO:0005654//nucleoplasm;GO:0016607//nuclear speck;GO:0005737//cytoplasm;GO:0046540//U4/U6 x U5 tri-snRNP complex;GO:0071013//catalytic step 2 spliceosome;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0015030//Cajal body","GO:0003723//RNA binding","GO:0000481//maturation of 5S rRNA;GO:0045585//positive regulation of cytotoxic T cell differentiation;GO:0000398//mRNA splicing, via spliceosome;GO:0045292//mRNA cis splicing, via spliceosome;GO:0097193//intrinsic apoptotic signaling pathway;GO:0007050//cell cycle arrest;GO:0000387//spliceosomal snRNP assembly","K11984//U4/U6.U5 tri-snRNP-associated protein 1","NP_005137.1//U4/U6.U5 tri-snRNP-associated protein 1 [Homo sapiens]",4]
[1666,1374,15.51,15.9,0.0358280791356269,1.01420085361598,"*",0.982392,"DECR1","GO:0005759//mitochondrial matrix;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005739//mitochondrion","GO:0016651//oxidoreductase activity, acting on NAD(P)H;GO:0008670//2,4-dienoyl-CoA reductase (NADPH) activity;GO:0070402//NADPH binding","GO:0006635//fatty acid beta-oxidation;GO:0051289//protein homotetramerization","K13236//2,4-dienoyl-CoA reductase, mitochondrial [EC:1.3.1.34]","NP_001317504.1//2,4-dienoyl-CoA reductase, mitochondrial isoform 2 [Homo sapiens];NP_001350.1//2,4-dienoyl-CoA reductase, mitochondrial isoform 1 precursor [Homo sapiens]","1//3"]
[79716,2181,18.68,19.14,0.0350963747763636,0.764104985040276,"*",0.665088,"NPEPL1","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0004177//aminopeptidase activity;GO:0008235//metalloexopeptidase activity;GO:0030145//manganese ion binding","NA","K09611//probable aminopeptidase NPEPL1 [EC:3.4.11.-]","NP_001191801.1//probable aminopeptidase NPEPL1 isoform 2 [Homo sapiens];NP_078939.3//probable aminopeptidase NPEPL1 isoform 1 [Homo sapiens];NP_001191802.1//probable aminopeptidase NPEPL1 isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[5754,4167,2.07,2.12,0.0344334970638741,0.973089164375529,"*",0.935016,"PTK7","GO:0005887//integral component of plasma membrane;GO:0005925//focal adhesion;GO:0005911//cell-cell junction","GO:1904929//coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway;GO:0005524//ATP binding;GO:0004672//protein kinase activity","GO:0016477//cell migration;GO:0060026//convergent extension;GO:0090103//cochlea morphogenesis;GO:0060484//lung-associated mesenchyme development;GO:0003281//ventricular septum development;GO:0060976//coronary vasculature development;GO:0031532//actin cytoskeleton reorganization;GO:0045198//establishment of epithelial cell apical/basal polarity;GO:0007165//signal transduction;GO:0090179//planar cell polarity pathway involved in neural tube closure;GO:0042060//wound healing;GO:0010976//positive regulation of neuron projection development;GO:0071300//cellular response to retinoic acid;GO:0007155//cell adhesion;GO:0060070//canonical Wnt signaling pathway;GO:0003401//axis elongation;GO:0001736//establishment of planar polarity","K05127//PTK7 protein tyrosine kinase 7 [EC:2.7.10.1]","NP_001257327.1//inactive tyrosine-protein kinase 7 isoform e [Homo sapiens];NP_690619.1//inactive tyrosine-protein kinase 7 isoform b precursor [Homo sapiens];XP_011927673.1//PREDICTED: inactive tyrosine-protein kinase 7 isoform X2 [Cercocebus atys];NP_690621.1//inactive tyrosine-protein kinase 7 isoform d precursor [Homo sapiens];NP_690620.1//inactive tyrosine-protein kinase 7 isoform c precursor [Homo sapiens]","4;1//3;3//A2MP1"]
[7448,1678,5.87,6.01,0.0340044876011333,0.897114159151906,"*",0.837022,"VTN","GO:0043231//intracellular membrane-bounded organelle;GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0072562//blood microparticle;GO:0005578//proteinaceous extracellular matrix;GO:0005796//Golgi lumen;GO:0005576//extracellular region;GO:0048237//rough endoplasmic reticulum lumen;GO:0071062//alphav-beta3 integrin-vitronectin complex;GO:0005604//basement membrane","GO:0005044//scavenger receptor activity;GO:0005178//integrin binding;GO:0005518//collagen binding;GO:0030247//polysaccharide binding;GO:0042802//identical protein binding;GO:0008201//heparin binding;GO:0050840//extracellular matrix binding","GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0030449//regulation of complement activation;GO:0010951//negative regulation of endopeptidase activity;GO:0097421//liver regeneration;GO:0035987//endodermal cell differentiation;GO:0033627//cell adhesion mediated by integrin;GO:0032092//positive regulation of protein binding;GO:0010811//positive regulation of cell-substrate adhesion;GO:0014911//positive regulation of smooth muscle cell migration;GO:0030195//negative regulation of blood coagulation;GO:0048709//oligodendrocyte differentiation;GO:0030949//positive regulation of vascular endothelial growth factor receptor signaling pathway;GO:0051258//protein polymerization;GO:0007160//cell-matrix adhesion;GO:0090303//positive regulation of wound healing;GO:0007155//cell adhesion;GO:0061302//smooth muscle cell-matrix adhesion;GO:0030198//extracellular matrix organization;GO:0006955//immune response;GO:0048260//positive regulation of receptor-mediated endocytosis","K06251//vitronectin","NP_000629.3//vitronectin precursor [Homo sapiens]","3//A2MP1"]
[7319,1869,70.27,71.92,0.0334841222906068,0.724544141543027,"*",0.611422,"UBE2A","NA","NA","NA","K10573//ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]","XP_008017611.1//PREDICTED: ubiquitin-conjugating enzyme E2 A isoform X2 [Chlorocebus sabaeus];XP_003931121.2//PREDICTED: ubiquitin-conjugating enzyme E2 A [Saimiri boliviensis boliviensis];ACQ58139.1//Ubiquitin-conjugating enzyme E2 A [Anoplopoma fimbria]","1//3;3//A2MP1;2//1"]
[57016,1610,1750.18,1791.12,0.0333586911535569,0.00261140688797364,"*",0.000793852,"AKR1B10","NA","NA","NA","K00011//aldehyde reductase [EC:1.1.1.21]","XP_007981173.1//PREDICTED: aldo-keto reductase family 1 member B10-like isoform X2 [Chlorocebus sabaeus]",4]
[81691,2796,2.2,2.25,0.0324214776923774,0.965724519490695,"*",0.925884,"REXO5","GO:0070062//extracellular exosome;GO:0005730//nucleolus","GO:0003723//RNA binding;GO:0004527//exonuclease activity","NA","K14570//RNA exonuclease 1 [EC:3.1.-.-]","NP_112203.2//RNA exonuclease 5 isoform 1 [Homo sapiens];NP_001138396.1//RNA exonuclease 5 isoform 2 [Homo sapiens]","1//3;2//1"]
[84433,4432,0.89,0.91,0.0320612092322986,0.955834349164756,"*",0.91341,"CARD11","GO:0042101//T cell receptor complex;GO:0070062//extracellular exosome;GO:0045121//membrane raft;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0001772//immunological synapse;GO:0005737//cytoplasm","GO:0050700//CARD domain binding;GO:0004385//guanylate kinase activity","GO:0042102//positive regulation of T cell proliferation;GO:0045580//regulation of T cell differentiation;GO:0031295//T cell costimulation;GO:0001819//positive regulation of cytokine production;GO:0030890//positive regulation of B cell proliferation;GO:0030183//B cell differentiation;GO:0050776//regulation of immune response;GO:0048872//homeostasis of number of cells;GO:0045061//thymic T cell selection;GO:0007165//signal transduction;GO:0045577//regulation of B cell differentiation;GO:0050852//T cell receptor signaling pathway;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0002377//immunoglobulin production;GO:0070970//interleukin-2 secretion;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0045086//positive regulation of interleukin-2 biosynthetic process;GO:0042100//B cell proliferation;GO:0042981//regulation of apoptotic process","K07367//caspase recruitment domain-containing protein 11","NP_115791.3//caspase recruitment domain-containing protein 11 [Homo sapiens]","1//3;5"]
[8428,4634,22.37,22.87,0.0318911093525536,0.659829987602357,"*",0.539752,"STK24","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005794//Golgi apparatus","GO:0046872//metal ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0008349//MAP kinase kinase kinase kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0045296//cadherin binding","GO:0007165//signal transduction;GO:0007346//regulation of mitotic cell cycle;GO:0009267//cellular response to starvation;GO:0008631//intrinsic apoptotic signaling pathway in response to oxidative stress;GO:0006468//protein phosphorylation;GO:0030336//negative regulation of cell migration;GO:0042542//response to hydrogen peroxide;GO:0046777//protein autophosphorylation;GO:0097194//execution phase of apoptosis;GO:0048812//neuron projection morphogenesis;GO:0048679//regulation of axon regeneration;GO:0031098//stress-activated protein kinase signaling cascade;GO:0042981//regulation of apoptotic process","K08838//serine/threonine-protein kinase 24/25/MST4 [EC:2.7.11.1]","NP_003567.2//serine/threonine-protein kinase 24 isoform a precursor [Homo sapiens];XP_020145852.1//serine/threonine-protein kinase 24 isoform X1 [Microcebus murinus]","4;1//3;3//A2MP1"]
[64838,1697,2.28,2.33,0.0312961304895385,0.954840431801796,"*",0.911982,"FNDC4","GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","NA","GO:0071559//response to transforming growth factor beta;GO:0050728//negative regulation of inflammatory response","K19719//collagen, type II, alpha;K16628//collagen, type VII, alpha;K05120//tyrosine kinase receptor 1 [EC:2.7.10.1]","XP_017380232.1//PREDICTED: LOW QUALITY PROTEIN: fibronectin type III domain-containing protein 4, partial [Cebus capucinus imitator]","2//1"]
[84667,1699,1.39,1.42,0.0308060467811744,0.939764134890781,"*",0.891464,"HES7","GO:0005634//nucleus","GO:0003677//DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0008134//transcription factor binding;GO:0046983//protein dimerization activity","GO:0007498//mesoderm development;GO:0006351//transcription, DNA-templated;GO:0048511//rhythmic process;GO:0036342//post-anal tail morphogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0014807//regulation of somitogenesis;GO:0001756//somitogenesis;GO:0007219//Notch signaling pathway;GO:0001501//skeletal system development","K09087//hairy and enhancer of split 2/6/7","XP_016880721.1//PREDICTED: transcription factor HES-7 isoform X1 [Homo sapiens];NP_115969.2//transcription factor HES-7 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[55829,1267,31.29,31.96,0.0305657496870551,0.81293585006993,"*",0.727744,"SELENOS","GO:0005783//endoplasmic reticulum;GO:0005881//cytoplasmic microtubule;GO:0034362//low-density lipoprotein particle;GO:0036502//Derlin-1-VIMP complex;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0034361//very-low-density lipoprotein particle;GO:0036513//Derlin-1 retrotranslocation complex;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane","GO:0016209//antioxidant activity;GO:0004872//receptor activity;GO:0051117//ATPase binding;GO:1990381//ubiquitin-specific protease binding;GO:0019899//enzyme binding","GO:0030970//retrograde protein transport, ER to cytosol;GO:0006111//regulation of gluconeogenesis;GO:0016567//protein ubiquitination;GO:0032715//negative regulation of interleukin-6 production;GO:0071222//cellular response to lipopolysaccharide;GO:0032720//negative regulation of tumor necrosis factor production;GO:0051771//negative regulation of nitric-oxide synthase biosynthetic process;GO:2000110//negative regulation of macrophage apoptotic process;GO:0050728//negative regulation of inflammatory response;GO:0045454//cell redox homeostasis;GO:0002865//negative regulation of acute inflammatory response to antigenic stimulus;GO:0009749//response to glucose;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0045184//establishment of protein localization;GO:0046325//negative regulation of glucose import;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0006886//intracellular protein transport;GO:0051775//response to redox state;GO:0032869//cellular response to insulin stimulus;GO:0045719//negative regulation of glycogen biosynthetic process;GO:0034599//cellular response to oxidative stress;GO:0080164//regulation of nitric oxide metabolic process;GO:0006983//ER overload response;GO:1902236//negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway","K14025//selenoprotein S","NP_060915.2//selenoprotein S isoform 1 [Homo sapiens]","2//1;5"]
[10131,2275,104.87,107.03,0.0294132064902876,0.746351442015347,"*",0.64543,"TRAP1","GO:0005759//mitochondrial matrix;GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005654//nucleoplasm;GO:0005811//lipid droplet;GO:0005758//mitochondrial intermembrane space;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0005164//tumor necrosis factor receptor binding;GO:0003723//RNA binding;GO:0005524//ATP binding;GO:0051082//unfolded protein binding;GO:0019901//protein kinase binding","GO:0006457//protein folding;GO:1901856//negative regulation of cellular respiration;GO:1903427//negative regulation of reactive oxygen species biosynthetic process;GO:1903751//negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide;GO:0006950//response to stress;GO:0009386//translational attenuation;GO:0061077//chaperone-mediated protein folding","K09488//TNF receptor-associated protein 1","NP_001258978.1//heat shock protein 75 kDa, mitochondrial isoform 2 [Homo sapiens];XP_004057143.1//PREDICTED: heat shock protein 75 kDa, mitochondrial [Gorilla gorilla gorilla]","1//3;2//1"]
[55190,2413,1.49,1.52,0.028758992981424,0.889562883351293,"*",0.826858,"NUDT11","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005737//cytoplasm","GO:0052841//inositol bisdiphosphate tetrakisphosphate diphosphatase activity;GO:0050072//m7G(5')pppN diphosphatase activity;GO:0052844//inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity;GO:0034431//bis(5'-adenosyl)-hexaphosphatase activity;GO:0016787//hydrolase activity;GO:0008486//diphosphoinositol-polyphosphate diphosphatase activity;GO:0052842//inositol diphosphate pentakisphosphate diphosphatase activity;GO:0052843//inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity;GO:0052845//inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity;GO:0052848//inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity;GO:0052846//inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity;GO:0046872//metal ion binding;GO:0000298//endopolyphosphatase activity;GO:0034432//bis(5'-adenosyl)-pentaphosphatase activity;GO:0052847//inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity;GO:0052840//inositol diphosphate tetrakisphosphate diphosphatase activity","GO:0071543//diphosphoinositol polyphosphate metabolic process;GO:0043647//inositol phosphate metabolic process;GO:1901907//diadenosine pentaphosphate catabolic process;GO:1901911//adenosine 5'-(hexahydrogen pentaphosphate) catabolic process;GO:1901909//diadenosine hexaphosphate catabolic process","K07766//diphosphoinositol-polyphosphate diphosphatase [EC:3.6.1.52]","NP_060629.2//diphosphoinositol polyphosphate phosphohydrolase 3-beta [Homo sapiens]","3//A2MP1"]
[339983,5894,8.01,8.17,0.0285338357369734,0.794536006209865,"*",0.704856,"NAT8L","GO:0005759//mitochondrial matrix;GO:0030867//rough endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0031966//mitochondrial membrane;GO:0005737//cytoplasm","GO:0017188//aspartate N-acetyltransferase activity","GO:0008652//cellular amino acid biosynthetic process","K18309//aspartate N-acetyltransferase [EC:2.3.1.17]","NP_848652.2//N-acetylaspartate synthetase [Homo sapiens]","3//A2MP1"]
[4836,4916,44.35,45.21,0.027707813130554,0.58286493764988,"*",0.426038,"NMT1","GO:0019898//extrinsic component of membrane;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0019107//myristoyltransferase activity;GO:0004379//glycylpeptide N-tetradecanoyltransferase activity","GO:1900740//positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway;GO:0018008//N-terminal peptidyl-glycine N-myristoylation;GO:0006499//N-terminal protein myristoylation;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0001701//in utero embryonic development;GO:0042180//cellular ketone metabolic process","K00671//glycylpeptide N-tetradecanoyltransferase [EC:2.3.1.97]","XP_008010555.1//PREDICTED: glycylpeptide N-tetradecanoyltransferase 1 [Chlorocebus sabaeus]",4]
[22928,2351,38.31,39.05,0.0276015226054614,0.72484572026105,"*",0.611858,"SEPHS2","GO:0005829//cytosol","GO:0005524//ATP binding;GO:0004756//selenide, water dikinase activity","GO:0016260//selenocysteine biosynthetic process;GO:0001887//selenium compound metabolic process;GO:0016259//selenocysteine metabolic process","K01008//selenide, water dikinase [EC:2.7.9.3]","NP_036380.2//selenide, water dikinase 2 [Homo sapiens]","3//A2MP1"]
[84932,2889,15.31,15.6,0.0270717462498229,0.875740109748662,"*",0.80924,"RAB2B","GO:0070062//extracellular exosome;GO:0098793//presynapse;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0000139//Golgi membrane","GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0045921//positive regulation of exocytosis;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport","K07878//Ras-related protein Rab-2B","XP_014998743.1//PREDICTED: ras-related protein Rab-2B isoform X2 [Macaca mulatta];NP_116235.2//ras-related protein Rab-2B isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[100507607,1491,8.59,8.75,0.0266248855812277,0.90996768727467,"*",0.85323,"NPIPB9","GO:0005654//nucleoplasm","NA","NA","K01896//medium-chain acyl-CoA synthetase [EC:6.2.1.2]","NP_001274180.1//nuclear pore complex-interacting protein family member B9 isoform 2 [Homo sapiens];NP_001274179.1//nuclear pore complex-interacting protein family member B9 isoform 1 [Homo sapiens]","1//3"]
[1445,2754,46.35,47.2,0.0262175207363105,0.678339119332828,"*",0.560116,"CSK","GO:0070062//extracellular exosome;GO:0045121//membrane raft;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0005829//cytosol;GO:0005911//cell-cell junction;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0042802//identical protein binding;GO:0019903//protein phosphatase binding;GO:0005102//receptor binding;GO:0046872//metal ion binding;GO:0004713//protein tyrosine kinase activity;GO:0008022//protein C-terminus binding;GO:0034236//protein kinase A catalytic subunit binding;GO:0070064//proline-rich region binding","GO:0038083//peptidyl-tyrosine autophosphorylation;GO:0042127//regulation of cell proliferation;GO:0032715//negative regulation of interleukin-6 production;GO:0031295//T cell costimulation;GO:0007420//brain development;GO:0045779//negative regulation of bone resorption;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0050765//negative regulation of phagocytosis;GO:0045087//innate immune response;GO:0008285//negative regulation of cell proliferation;GO:0010989//negative regulation of low-density lipoprotein particle clearance;GO:0030154//cell differentiation;GO:0050852//T cell receptor signaling pathway;GO:0043406//positive regulation of MAP kinase activity;GO:0006468//protein phosphorylation;GO:0042997//negative regulation of Golgi to plasma membrane protein transport;GO:0048709//oligodendrocyte differentiation;GO:0007417//central nervous system development;GO:0033673//negative regulation of kinase activity;GO:0046777//protein autophosphorylation;GO:0002250//adaptive immune response;GO:0071375//cellular response to peptide hormone stimulus;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0001817//regulation of cytokine production;GO:0034332//adherens junction organization;GO:0060368//regulation of Fc receptor mediated stimulatory signaling pathway","K05728//c-src tyrosine kinase [EC:2.7.10.2]","EDL25918.1//c-src tyrosine kinase, isoform CRA_a, partial [Mus musculus]","1//3;2//1"]
[10671,1126,33.16,33.74,0.0250159667918157,0.845082363811357,"*",0.769536,"DCTN6","GO:0005869//dynactin complex;GO:0005829//cytosol;GO:0005813//centrosome;GO:0000777//condensed chromosome kinetochore","NA","GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0006888//ER to Golgi vesicle-mediated transport","K10428//dynactin 6","NP_006562.1//dynactin subunit 6 [Homo sapiens]","3//A2MP1"]
[54499,4490,21.31,21.68,0.0248341635711681,0.751088499747092,"*",0.650702,"TMCO1","GO:0005783//endoplasmic reticulum;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0000139//Golgi membrane","GO:0005262//calcium channel activity","GO:0070588//calcium ion transmembrane transport;GO:0032469//endoplasmic reticulum calcium ion homeostasis;GO:0006983//ER overload response","K21891//calcium load-activated calcium channel","NP_061899.2//calcium load-activated calcium channel isoform a [Homo sapiens];NP_001243093.1//calcium load-activated calcium channel isoform b [Homo sapiens];NP_001243094.1//calcium load-activated calcium channel isoform c [Homo sapiens]","4;1//3"]
[51593,3029,61.34,62.37,0.0240240923125063,0.637369392191728,"*",0.516112,"SRRT","NA","NA","NA","K19607//X-linked retinitis pigmentosa GTPase regulator","XP_005250464.1//PREDICTED: serrate RNA effector molecule homolog isoform X3 [Homo sapiens];XP_005250463.1//PREDICTED: serrate RNA effector molecule homolog isoform X2 [Homo sapiens];XP_005250462.1//PREDICTED: serrate RNA effector molecule homolog isoform X1 [Homo sapiens];XP_005250465.1//PREDICTED: serrate RNA effector molecule homolog isoform X4 [Homo sapiens]","1//3;5"]
[102723553,870,14.43,14.66,0.0228138036426139,0.942347081625931,"*",0.895448,"SMIM11B","NA","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K06245//laminin, beta 4;K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K01064//wingless-type MMTV integration site family, member 9","BAG64432.1//unnamed protein product [Homo sapiens]","1//3"]
[131870,3310,3.81,3.87,0.0225425686510882,3.23378248106366E-3,"*",1.004914E-3,"NUDT16","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm","GO:0030515//snoRNA binding;GO:0000287//magnesium ion binding;GO:0035870//dITP diphosphatase activity;GO:0003729//mRNA binding;GO:0050072//m7G(5')pppN diphosphatase activity;GO:0042802//identical protein binding;GO:1990003//IDP phosphatase activity;GO:0042803//protein homodimerization activity;GO:0098519//nucleotide phosphatase activity, acting on free nucleotides;GO:1901641//ITP binding;GO:0008235//metalloexopeptidase activity;GO:0050897//cobalt ion binding;GO:0016787//hydrolase activity;GO:0097383//dIDP diphosphatase activity;GO:0005525//GTP binding;GO:1901640//XTP binding;GO:0030145//manganese ion binding","GO:0006402//mRNA catabolic process;GO:0035863//dITP catabolic process;GO:2000233//negative regulation of rRNA processing;GO:0016077//snoRNA catabolic process;GO:0006382//adenosine to inosine editing;GO:0046709//IDP catabolic process;GO:0034656//nucleobase-containing small molecule catabolic process;GO:2000781//positive regulation of double-strand break repair;GO:0090068//positive regulation of cell cycle process;GO:1901639//XDP catabolic process;GO:0008284//positive regulation of cell proliferation","K16855//U8 snoRNA-decapping enzyme [EC:3.6.1.62 3.6.1.64]","NP_001165377.1//U8 snoRNA-decapping enzyme isoform 1 [Homo sapiens];NP_001165376.1//U8 snoRNA-decapping enzyme isoform 3 [Homo sapiens];NP_689608.2//U8 snoRNA-decapping enzyme isoform 2 [Homo sapiens]","1//3;2//1"]
[83596,1867,44,44.67,0.0218027308912343,0.758919260305564,"*",0.659244,"BCL2L12","GO:0016020//membrane;GO:0005634//nucleus","GO:0002039//p53 binding","GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:1902166//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:1990001//inhibition of cysteine-type endopeptidase activity involved in apoptotic process;GO:0042981//regulation of apoptotic process;GO:2000773//negative regulation of cellular senescence;GO:0006915//apoptotic process","K19720//collagen, type III, alpha","NP_001035758.1//bcl-2-like protein 12 isoform 3 [Homo sapiens];NP_001269448.1//bcl-2-like protein 12 isoform 5 [Homo sapiens];NP_001269449.1//bcl-2-like protein 12 isoform 6 [Homo sapiens];NP_001269446.1//bcl-2-like protein 12 isoform 2 [Homo sapiens];NP_001269450.1//bcl-2-like protein 12 isoform 7 [Homo sapiens];NP_001269445.1//bcl-2-like protein 12 isoform 4 [Homo sapiens];NP_619580.1//bcl-2-like protein 12 isoform 1 [Homo sapiens]","1//3"]
[4968,1832,20.84,21.15,0.0213023857288039,0.650643082314964,"*",0.529956,"OGG1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0043234//protein complex;GO:0016607//nuclear speck;GO:0016363//nuclear matrix;GO:0005739//mitochondrion","GO:0008017//microtubule binding;GO:0016829//lyase activity;GO:0003684//damaged DNA binding;GO:0034039//8-oxo-7,8-dihydroguanine DNA N-glycosylase activity;GO:0140078//class I DNA-(apurinic or apyrimidinic site) lyase activity;GO:0019104//DNA N-glycosylase activity;GO:0032357//oxidized purine DNA binding;GO:0140080//class III/IV DNA-(apurinic or apyrimidinic site) lyase activity;GO:0004519//endonuclease activity;GO:0008534//oxidized purine nucleobase lesion DNA N-glycosylase activity","GO:0006284//base-excision repair;GO:0006355//regulation of transcription, DNA-templated;GO:0009416//response to light stimulus;GO:1901291//negative regulation of double-strand break repair via single-strand annealing;GO:0006289//nucleotide-excision repair;GO:0045471//response to ethanol;GO:0033158//regulation of protein import into nucleus, translocation;GO:0045007//depurination;GO:0032355//response to estradiol;GO:0045008//depyrimidination;GO:0051593//response to folic acid;GO:0033683//nucleotide-excision repair, DNA incision;GO:0071276//cellular response to cadmium ion;GO:0006974//cellular response to DNA damage stimulus;GO:0042493//response to drug;GO:0043066//negative regulation of apoptotic process;GO:0002526//acute inflammatory response;GO:0007568//aging;GO:0006979//response to oxidative stress;GO:0009314//response to radiation","K03660//N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]","NP_058438.1//N-glycosylase/DNA lyase isoform 2e [Homo sapiens];NP_058213.1//N-glycosylase/DNA lyase isoform 1c [Homo sapiens];NP_001341578.1//N-glycosylase/DNA lyase isoform 1e [Homo sapiens];NP_002533.1//N-glycosylase/DNA lyase isoform 1a [Homo sapiens];NP_001341577.1//N-glycosylase/DNA lyase isoform 1d [Homo sapiens];NP_058436.1//N-glycosylase/DNA lyase isoform 2c [Homo sapiens];NP_058437.1//N-glycosylase/DNA lyase isoform 2d [Homo sapiens];NP_058214.1//N-glycosylase/DNA lyase isoform 2a [Homo sapiens];NP_001341580.1//N-glycosylase/DNA lyase isoform 2g [Homo sapiens];NP_058434.1//N-glycosylase/DNA lyase isoform 2b [Homo sapiens];NP_001341581.1//N-glycosylase/DNA lyase isoform 2h [Homo sapiens];XP_009198515.1//N-glycosylase/DNA lyase isoform X1 [Papio anubis];NP_001341579.1//N-glycosylase/DNA lyase isoform 2f [Homo sapiens]","1//3;3//A2MP1;2//1;5"]
[439921,2315,49.22,49.93,0.0206622488719328,0.818878736081184,"*",0.737524,"MXRA7","NA","NA","NA","K16628//collagen, type VII, alpha;K01064//wingless-type MMTV integration site family, member 9","XP_011897738.1//PREDICTED: matrix-remodeling-associated protein 7 isoform X4 [Cercocebus atys];XP_011897735.1//PREDICTED: matrix-remodeling-associated protein 7 isoform X2 [Cercocebus atys];XP_011897737.1//PREDICTED: matrix-remodeling-associated protein 7 isoform X3 [Cercocebus atys]","3//A2MP1;2//1"]
[158067,2197,0.72,0.73,0.0198995574377048,0.923237545617649,"*",0.869776,"AK8","GO:0036126//sperm flagellum;GO:0005829//cytosol;GO:0005930//axoneme","GO:0005524//ATP binding;GO:0019206//nucleoside kinase activity;GO:0004550//nucleoside diphosphate kinase activity;GO:0004127//cytidylate kinase activity;GO:0004017//adenylate kinase activity","GO:0006165//nucleoside diphosphate phosphorylation;GO:0021591//ventricular system development;GO:0015949//nucleobase-containing small molecule interconversion;GO:0009142//nucleoside triphosphate biosynthetic process","K00939//adenylate kinase [EC:2.7.4.3]","NP_689785.1//adenylate kinase 8 isoform 1 [Homo sapiens];NP_001304888.1//adenylate kinase 8 isoform 3 [Homo sapiens]","1//3;2//1"]
[11282,2528,108.45,109.93,0.0195550998374388,0.697301390912505,"*",0.58123,"MGAT4B","GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0008375//acetylglucosaminyltransferase activity;GO:0046872//metal ion binding;GO:0016758//transferase activity, transferring hexosyl groups;GO:0008454//alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity","GO:0006487//protein N-linked glycosylation;GO:0005975//carbohydrate metabolic process;GO:0006491//N-glycan processing","K00738//alpha-1,3-mannosylglycoprotein beta-1,4-N-acetylglucosaminyltransferase A/B [EC:2.4.1.145]","EAW53789.1//mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B, isoform CRA_b [Homo sapiens];NP_463459.1//alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B isoform 2 [Homo sapiens]","4;3//A2MP1"]
[4289,11201,5.32,5.39,0.0188590272513158,0.858979409710857,"*",0.788536,"MKLN1","GO:0001726//ruffle;GO:0005938//cell cortex;GO:0005829//cytosol","GO:0042802//identical protein binding","GO:0007160//cell-matrix adhesion;GO:0031532//actin cytoskeleton reorganization;GO:0007165//signal transduction;GO:0008360//regulation of cell shape","K17985//activating molecule in BECN1-regulated autophagy protein 1;K15696//RING finger protein 113B","XP_003791660.2//PREDICTED: muskelin [Otolemur garnettii];XP_004608311.1//PREDICTED: muskelin [Sorex araneus]","4;1//3"]
[64925,1851,10.6,10.73,0.0175858113059605,0.927922887134231,"*",0.875468,"CCDC71","NA","NA","NA","K06243//laminin, beta 2;K11275//histone H1/5","NP_075054.3//coiled-coil domain-containing protein 71 [Homo sapiens]","3//A2MP1"]
[377,3556,100.09,101.3,0.0173363325434042,0.625768583820891,"*",0.502174,"ARF3","NA","NA","NA","K07938//ADP-ribosylation factor 3","ELK08405.1//Protein Wnt-10b [Pteropus alecto]","2//1"]
[79180,2424,106.28,107.51,0.0166007248218602,0.698516790449733,"*",0.582418,"EFHD2","GO:0045121//membrane raft","GO:0005509//calcium ion binding;GO:0045296//cadherin binding","NA","K17336//plastin-3;K19475//WAS/WASL-interacting protein;K01311//chymotrypsin C [EC:3.4.21.2]","NP_077305.2//EF-hand domain-containing protein D2 [Homo sapiens]",5]
[11273,3987,118.75,120.04,0.0155877106052535,0.60859171261939,"*",0.450748,"ATXN2L","GO:0016020//membrane;GO:0010494//cytoplasmic stress granule;GO:0005829//cytosol;GO:0016607//nuclear speck","GO:0003723//RNA binding;GO:0045296//cadherin binding","GO:0034063//stress granule assembly;GO:0010603//regulation of cytoplasmic mRNA processing body assembly","K11653//AT-rich interactive domain-containing protein 1;K21125//mucin-5AC;K09188//histone-lysine N-methyltransferase MLL3 [EC:2.1.1.43]","XP_012360621.1//PREDICTED: ataxin-2-like protein [Nomascus leucogenys];NP_009176.2//ataxin-2-like protein isoform A [Homo sapiens];NP_059867.3//ataxin-2-like protein isoform F [Homo sapiens];NP_001295159.1//ataxin-2-like protein isoform G [Homo sapiens];NP_663760.1//ataxin-2-like protein isoform B [Homo sapiens];NP_680780.1//ataxin-2-like protein isoform C [Homo sapiens]","1//3;3//A2MP1;2//1"]
[128272,3357,1.92,1.94,0.0149503414659716,0.967401787234042,"*",0.927916,"ARHGEF19","GO:0005829//cytosol","GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity","GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0043065//positive regulation of apoptotic process;GO:0042060//wound healing;GO:0043547//positive regulation of GTPase activity;GO:0035023//regulation of Rho protein signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0032956//regulation of actin cytoskeleton organization","K20691//Rho guanine nucleotide exchange factor 19","XP_009447334.2//PREDICTED: rho guanine nucleotide exchange factor 19 isoform X1 [Pan troglodytes]",4]
[7323,4124,53.49,54.03,0.014491478281281,0.860082673120185,"*",0.789818,"UBE2D3","GO:0070062//extracellular exosome;GO:0010008//endosome membrane;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0005524//ATP binding;GO:0061631//ubiquitin conjugating enzyme activity;GO:0004842//ubiquitin-protein transferase activity","GO:0070936//protein K48-linked ubiquitination;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:1903955//positive regulation of protein targeting to mitochondrion;GO:0016567//protein ubiquitination;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0051865//protein autoubiquitination;GO:0000209//protein polyubiquitination;GO:0006281//DNA repair;GO:0006513//protein monoubiquitination;GO:0030509//BMP signaling pathway;GO:0070979//protein K11-linked ubiquitination;GO:0006915//apoptotic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0006464//cellular protein modification process","K06689//ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]","NP_871622.1//ubiquitin-conjugating enzyme E2 D3 isoform 3 [Homo sapiens];XP_021251741.1//ubiquitin-conjugating enzyme E2 D3 isoform X1 [Numida meleagris];XP_021565848.1//ubiquitin-conjugating enzyme E2 D3 isoform X4 [Carlito syrichta]","6;1//3;3//A2MP1;2//1"]
[221002,3243,1.07,1.08,0.0134205157623218,1.02205801224621,"*",0.99269,"RASGEF1A","GO:0005829//cytosol;GO:0005622//intracellular","GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005085//guanyl-nucleotide exchange factor activity","GO:0000165//MAPK cascade;GO:0016477//cell migration;GO:0046579//positive regulation of Ras protein signal transduction;GO:0007264//small GTPase mediated signal transduction","K08020//Rap guanine nucleotide exchange factor 6;K03781//catalase [EC:1.11.1.6];K08018//Rap guanine nucleotide exchange factor 2;K03099//son of sevenless","NP_001269791.1//ras-GEF domain-containing family member 1A isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[1140,2437,4.3,4.34,0.013358382855019,0.975407697553358,"*",0.938404,"CHRNB1","GO:0005887//integral component of plasma membrane;GO:0005892//acetylcholine-gated channel complex;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0045202//synapse;GO:0045211//postsynaptic membrane","GO:0015276//ligand-gated ion channel activity;GO:0042166//acetylcholine binding;GO:0015267//channel activity;GO:0022848//acetylcholine-gated cation-selective channel activity","GO:0035095//behavioral response to nicotine;GO:0007165//signal transduction;GO:0006936//muscle contraction;GO:0098655//cation transmembrane transport;GO:0048747//muscle fiber development;GO:0006812//cation transport;GO:0007274//neuromuscular synaptic transmission;GO:0007271//synaptic transmission, cholinergic;GO:0001941//postsynaptic membrane organization;GO:0003009//skeletal muscle contraction;GO:0050877//nervous system process;GO:0042391//regulation of membrane potential","K04812//nicotinic acetylcholine receptor beta-1","NP_000738.2//acetylcholine receptor subunit beta precursor [Homo sapiens]","2//1"]
[26524,5558,3.41,3.44,0.0126368256779255,0.953895753688766,"*",0.910602,"LATS2","GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005815//microtubule organizing center;GO:0005829//cytosol","GO:0046872//metal ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding","GO:0046620//regulation of organ growth;GO:0035329//hippo signaling;GO:0006468//protein phosphorylation;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0035556//intracellular signal transduction;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0018105//peptidyl-serine phosphorylation;GO:0051301//cell division;GO:0000082//G1/S transition of mitotic cell cycle;GO:0009755//hormone-mediated signaling pathway","K08791//serine/threonine-protein kinase LATS1/2 [EC:2.7.11.1]","NP_055387.2//serine/threonine-protein kinase LATS2 [Homo sapiens]","2//1"]
[728642,3212,7,7.06,0.0123132614388513,0.95667254812099,"*",0.91475,"CDK11A","NA","NA","NA","K08818//cell division cycle 2-like [EC:2.7.11.22]","XP_016807764.1//PREDICTED: cyclin-dependent kinase 11B isoform X8 [Pan troglodytes];XP_016807743.1//PREDICTED: cyclin-dependent kinase 11B isoform X5 [Pan troglodytes];EDL15018.1//cell division cycle 2-like 1, isoform CRA_b, partial [Mus musculus];AAC72077.1//PITSLRE protein kinase alpha SV1 isoform [Homo sapiens]","1//3;3//A2MP1"]
[7088,4150,25.69,25.91,0.0123021252792775,0.862772183823529,"*",0.793314,"TLE1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol","GO:0001106//RNA polymerase II transcription corepressor activity;GO:0042802//identical protein binding;GO:0008134//transcription factor binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0007165//signal transduction;GO:0006355//regulation of transcription, DNA-templated;GO:0030178//negative regulation of Wnt signaling pathway;GO:0006351//transcription, DNA-templated;GO:0010628//positive regulation of gene expression;GO:1904837//beta-catenin-TCF complex assembly;GO:2000811//negative regulation of anoikis;GO:0009887//animal organ morphogenesis;GO:0007275//multicellular organism development;GO:0016055//Wnt signaling pathway;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling","K04497//groucho","XP_020822580.1//transducin-like enhancer protein 1 isoform X4 [Phascolarctos cinereus];XP_020822577.1//transducin-like enhancer protein 1 isoform X1 [Phascolarctos cinereus];XP_020822582.1//transducin-like enhancer protein 1 isoform X6 [Phascolarctos cinereus]","4;1//3"]
[11266,1283,22.66,22.84,0.0114147895423272,0.939113822768093,"*",0.890318,"DUSP12","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0008270//zinc ion binding;GO:0019900//kinase binding;GO:0004725//protein tyrosine phosphatase activity;GO:0016791//phosphatase activity;GO:0003676//nucleic acid binding","GO:0006464//cellular protein modification process;GO:0016311//dephosphorylation;GO:0033133//positive regulation of glucokinase activity","K14819//dual specificity phosphatase 12 [EC:3.1.3.16 3.1.3.48]","XP_514446.3//PREDICTED: dual specificity protein phosphatase 12 [Pan troglodytes]","2//1"]
[10001,2386,15.26,15.37,0.0103622028562407,0.924705559835303,"*",0.87168,"MED6","GO:0016020//membrane;GO:0070847//core mediator complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000151//ubiquitin ligase complex;GO:0016592//mediator complex","GO:0061630//ubiquitin protein ligase activity;GO:0003677//DNA binding;GO:0003713//transcription coactivator activity;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0001128//RNA polymerase II transcription coactivator activity involved in preinitiation complex assembly;GO:0008134//transcription factor binding","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0019827//stem cell population maintenance;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0051123//RNA polymerase II transcriptional preinitiation complex assembly","K15128//mediator of RNA polymerase II transcription subunit 6","XP_005321246.1//mediator of RNA polymerase II transcription subunit 6 isoform X2 [Ictidomys tridecemlineatus];NP_005457.2//mediator of RNA polymerase II transcription subunit 6 isoform 2 [Homo sapiens];NP_001271140.1//mediator of RNA polymerase II transcription subunit 6 isoform 4 [Homo sapiens];NP_001271138.1//mediator of RNA polymerase II transcription subunit 6 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[5877,3227,10.11,10.18,0.00995456417268062,0.962711145321485,"*",0.922332,"RABIF","NA","NA","NA","K19952//guanine nucleotide exchange factor","XP_017752084.1//PREDICTED: guanine nucleotide exchange factor MSS4 [Rhinopithecus bieti]",4]
[100144595,2362,1.63,1.64,0.00882385038700641,1.02205792263056,"*",0.99237,"LOC100144595","NA","NA","NA","K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K01064//wingless-type MMTV integration site family, member 9;K12025//tripartite motif-containing protein 52","EAX11463.1//hCG2038403, partial [Homo sapiens]","1//3"]
[10424,3790,20.14,20.26,0.00857049079435359,0.91332654518795,"*",0.857866,"PGRMC2","GO:0012505//endomembrane system;GO:0016020//membrane;GO:0005635//nuclear envelope;GO:0016021//integral component of membrane","GO:0003707//steroid hormone receptor activity;GO:0020037//heme binding;GO:0005496//steroid binding","NA","K17278//membrane-associated progesterone receptor component","XP_005631865.2//membrane-associated progesterone receptor component 2, partial [Canis lupus familiaris]",4]
[441518,2038,6.83,6.87,0.00842452052800982,0.978960645823854,"*",0.942864,"RTL8B","NA","NA","NA","K19720//collagen, type III, alpha","EAX11737.1//hCG14613, isoform CRA_a, partial [Homo sapiens]","1//3"]
[56731,2296,108.71,109.21,0.00662030824394461,0.860267955555556,"*",0.790042,"SLC2A4RG","GO:0005634//nucleus;GO:0016607//nuclear speck;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0001158//enhancer sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K22020//mucin-19","NP_064446.2//SLC2A4 regulator [Homo sapiens]","3//A2MP1"]
[84513,1329,22.59,22.68,0.00573636954914447,0.375624997788945,"*",0.233972,"PLPP5","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0008195//phosphatidate phosphatase activity","GO:0007165//signal transduction;GO:0046839//phospholipid dephosphorylation;GO:0006644//phospholipid metabolic process","K18693//diacylglycerol diphosphate phosphatase / phosphatidate phosphatase [EC:3.1.3.81 3.1.3.4]","XP_011542974.1//PREDICTED: phospholipid phosphatase 5 isoform X5 [Homo sapiens];XP_519712.3//PREDICTED: phospholipid phosphatase 5 isoform X1 [Pan troglodytes];NP_001096030.1//phospholipid phosphatase 5 isoform 3 [Homo sapiens];NP_001341386.1//phospholipid phosphatase 5 isoform 7 [Homo sapiens];NP_001341381.1//phospholipid phosphatase 5 isoform 4 [Homo sapiens];XP_001170536.2//PREDICTED: phospholipid phosphatase 5 isoform X2 [Pan troglodytes];XP_010383591.1//PREDICTED: phosphatidate phosphatase PPAPDC1B isoform X4 [Rhinopithecus roxellana];NP_001341383.1//phospholipid phosphatase 5 isoform 5 [Homo sapiens]","1//3;3//A2MP1"]
[25861,3870,2.72,2.73,0.00529429966951302,0.975391193804503,"*",0.938266,"WHRN","GO:0001917//photoreceptor inner segment;GO:0032391//photoreceptor connecting cilium;GO:0032426//stereocilium tip;GO:0005737//cytoplasm;GO:0005884//actin filament;GO:0036064//ciliary basal body;GO:1990075//periciliary membrane compartment;GO:0030426//growth cone;GO:0002142//stereocilia ankle link complex;GO:0032420//stereocilium;GO:1990696//USH2 complex","GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity","GO:0045184//establishment of protein localization;GO:0060088//auditory receptor cell stereocilium organization;GO:0001895//retina homeostasis;GO:1990227//paranodal junction maintenance;GO:0010628//positive regulation of gene expression;GO:0021694//cerebellar Purkinje cell layer formation;GO:0060122//inner ear receptor cell stereocilium organization;GO:0050953//sensory perception of light stimulus;GO:0007605//sensory perception of sound","K21879//whirlin","NP_001166896.1//whirlin isoform 3 [Homo sapiens];XP_011516786.1//PREDICTED: whirlin isoform X1 [Homo sapiens];NP_056219.3//whirlin isoform 1 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[5250,1691,215.15,215.86,0.00475308881719779,0.902274320835565,"*",0.843644,"SLC25A3","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0043209//myelin sheath;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0015114//phosphate ion transmembrane transporter activity;GO:0015293//symporter activity;GO:0032403//protein complex binding","GO:0006810//transport;GO:0006839//mitochondrial transport","K15102//solute carrier family 25 (mitochondrial phosphate transporter), member 3","NP_005879.1//phosphate carrier protein, mitochondrial isoform a precursor [Homo sapiens];NP_002626.1//phosphate carrier protein, mitochondrial isoform b precursor [Homo sapiens]","3//A2MP1;2//1"]
[28985,9797,7.05,7.07,0.00408695752324295,0.953950520393443,"*",0.910714,"MCTS1","GO:0005829//cytosol;GO:0022627//cytosolic small ribosomal subunit;GO:0005737//cytoplasm;GO:0005886//plasma membrane","GO:0003723//RNA binding;GO:0003743//translation initiation factor activity","GO:0075522//IRES-dependent viral translational initiation;GO:0002188//translation reinitiation;GO:0006355//regulation of transcription, DNA-templated;GO:0040008//regulation of growth;GO:0006351//transcription, DNA-templated;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0032790//ribosome disassembly;GO:0001731//formation of translation preinitiation complex","K07575//PUA domain protein","XP_019573218.1//PREDICTED: LOW QUALITY PROTEIN: malignant T-cell-amplified sequence 1-like [Rhinolophus sinicus];XP_019488830.1//PREDICTED: malignant T-cell-amplified sequence 1 [Hipposideros armiger]","1//3;2//1"]
[8480,1815,32.55,32.63,0.00354144403886669,0.968061711228551,"*",0.928852,"RAE1","NA","NA","NA","K14298//mRNA export factor","XP_017392061.1//PREDICTED: mRNA export factor [Cebus capucinus imitator];XP_005260640.1//PREDICTED: mRNA export factor isoform X3 [Homo sapiens]","1//3;3//A2MP1"]
[332,2626,80.03,80.19,2.88142907595624E-3,0.889530945922284,"*",0.826884,"BIRC5","GO:0005874//microtubule;GO:0005881//cytoplasmic microtubule;GO:0005737//cytoplasm;GO:0032133//chromosome passenger complex;GO:0030496//midbody;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005819//spindle;GO:0000777//condensed chromosome kinetochore;GO:0005876//spindle microtubule;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0000775//chromosome, centromeric region;GO:0005814//centriole;GO:0000228//nuclear chromosome;GO:0031021//interphase microtubule organizing center","GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process;GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity;GO:0051087//chaperone binding;GO:0042803//protein homodimerization activity;GO:0008017//microtubule binding;GO:0004842//ubiquitin-protein transferase activity;GO:0050897//cobalt ion binding;GO:0015631//tubulin binding;GO:0046872//metal ion binding;GO:0008536//Ran GTPase binding;GO:0008270//zinc ion binding;GO:0048037//cofactor binding;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0019899//enzyme binding","GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0016925//protein sumoylation;GO:0000278//mitotic cell cycle;GO:0007059//chromosome segregation;GO:0007346//regulation of mitotic cell cycle;GO:0016567//protein ubiquitination;GO:0051303//establishment of chromosome localization;GO:1990001//inhibition of cysteine-type endopeptidase activity involved in apoptotic process;GO:0031536//positive regulation of exit from mitosis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0031577//spindle checkpoint;GO:0000910//cytokinesis;GO:0045931//positive regulation of mitotic cell cycle;GO:0006468//protein phosphorylation;GO:0006351//transcription, DNA-templated;GO:0043066//negative regulation of apoptotic process;GO:0006915//apoptotic process;GO:0090307//mitotic spindle assembly;GO:0007062//sister chromatid cohesion;GO:0007605//sensory perception of sound;GO:0051301//cell division;GO:0009966//regulation of signal transduction;GO:0000086//G2/M transition of mitotic cell cycle;GO:0042981//regulation of apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0031503//protein complex localization","K08731//baculoviral IAP repeat-containing protein 5","AAA19687.1//effector cell protease receptor 1, partial [Homo sapiens];XP_008011275.1//PREDICTED: baculoviral IAP repeat-containing protein 5 isoform X2 [Chlorocebus sabaeus]","1//3;2//1"]
[64968,1017,24.06,24.09,0.00179775106239416,1.01350608846353,"*",0.981148,"MRPS6","NA","NA","NA","K02990//small subunit ribosomal protein S6;K14383//solute carrier family 5 (sodium/myo-inositol cotransporter), member 3","XP_531445.5//PREDICTED: 28S ribosomal protein S6, mitochondrial [Pan troglodytes]","3//A2MP1"]
[64342,2403,26.82,26.84,0.00107543429570972,0.983803946531698,"*",0.94913,"HS1BP3","GO:0005783//endoplasmic reticulum;GO:0005739//mitochondrion","GO:0035091//phosphatidylinositol binding","GO:0042981//regulation of apoptotic process","K03006//DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]","NP_071905.3//HCLS1-binding protein 3 [Homo sapiens]","3//A2MP1"]
[5223,1863,290.94,291.06,5.94925798487971E-4,0.938920558938123,"*",0.890076,"PGAM1","GO:0034774//secretory granule lumen;GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0043209//myelin sheath;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005576//extracellular region;GO:1904813//ficolin-1-rich granule lumen","GO:0004619//phosphoglycerate mutase activity;GO:0016787//hydrolase activity;GO:0004082//bisphosphoglycerate mutase activity;GO:0046538//2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity;GO:0019901//protein kinase binding","GO:0061621//canonical glycolysis;GO:0006094//gluconeogenesis;GO:0043312//neutrophil degranulation;GO:0006096//glycolytic process;GO:0043456//regulation of pentose-phosphate shunt;GO:0006110//regulation of glycolytic process;GO:0045730//respiratory burst","K01834//2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]","NP_001304008.1//phosphoglycerate mutase 1 isoform 2 [Homo sapiens];XP_017358259.1//PREDICTED: phosphoglycerate mutase 1 [Cebus capucinus imitator]","1//3;3//A2MP1"]
[286499,3292,0.1,0.1,0,1.01748933622781,"*",0.997616,"FAM133A","NA","NA","NA","K10779//transcriptional regulator ATRX [EC:3.6.4.12]","XP_007990408.1//PREDICTED: protein FAM133A [Chlorocebus sabaeus]","1//3;2//1"]
[11251,2910,0.38,0.38,0,1.02111780048787,"*",0.995804,"PTGDR2","GO:0005887//integral component of plasma membrane;GO:0005622//intracellular;GO:0005886//plasma membrane;GO:0043005//neuron projection","GO:0001785//prostaglandin J receptor activity;GO:0004958//prostaglandin F receptor activity;GO:0042923//neuropeptide binding;GO:0004956//prostaglandin D receptor activity;GO:0004930//G-protein coupled receptor activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0019722//calcium-mediated signaling;GO:0045745//positive regulation of G-protein coupled receptor protein signaling pathway;GO:2000255//negative regulation of male germ cell proliferation;GO:0007268//chemical synaptic transmission;GO:0006955//immune response;GO:0006935//chemotaxis;GO:0007218//neuropeptide signaling pathway;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger","K06715//G protein-coupled receptor 44","NP_004769.2//prostaglandin D2 receptor 2 [Homo sapiens]","2//1"]
[6660,5926,0.01,0.01,0,0.655284600739827,"*",0.499032,"SOX5","GO:0005634//nucleus","GO:0003677//DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0071560//cellular response to transforming growth factor beta stimulus;GO:2000741//positive regulation of mesenchymal stem cell differentiation;GO:0061036//positive regulation of cartilage development;GO:0006366//transcription from RNA polymerase II promoter;GO:0032332//positive regulation of chondrocyte differentiation;GO:0055059//asymmetric neuroblast division","K09269//transcription factor SOX5/6/13 (SOX group D)","XP_006727807.1//PREDICTED: transcription factor SOX-5 isoform X1 [Leptonychotes weddellii];XP_021584484.1//transcription factor SOX-5 isoform X1 [Ictidomys tridecemlineatus];NP_001248343.1//transcription factor SOX-5 isoform d [Homo sapiens];XP_007966099.1//PREDICTED: transcription factor SOX-5 isoform X2 [Chlorocebus sabaeus];NP_821078.1//transcription factor SOX-5 isoform c [Homo sapiens];XP_016875378.1//PREDICTED: transcription factor SOX-5 isoform X2 [Homo sapiens]","4;1//3;3//A2MP1;2//1;5"]
[57121,2716,0.03,0.03,0,1.01005608865248,"*",0.998548,"LPAR5","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004930//G-protein coupled receptor activity","NA","K08390//lysophosphatidic acid receptor 5","NP_065133.1//lysophosphatidic acid receptor 5 [Homo sapiens]","1//3;5"]
[83729,2480,0.87,0.87,0,1.02168244811837,"*",0.994244,"INHBE","GO:0005615//extracellular space;GO:0005576//extracellular region","GO:0008083//growth factor activity;GO:0005125//cytokine activity;GO:0005160//transforming growth factor beta receptor binding;GO:0005179//hormone activity","GO:0060395//SMAD protein signal transduction;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0043408//regulation of MAPK cascade;GO:0042981//regulation of apoptotic process;GO:0048468//cell development","K04667//inhibin, beta","NP_113667.1//inhibin beta E chain preproprotein [Homo sapiens]",4]
[146862,5354,0.01,0.01,0,1.0096085671245,"*",0.998548,"UNC45B","GO:0005829//cytosol","GO:0051879//Hsp90 protein binding","GO:0030154//cell differentiation;GO:0007517//muscle organ development;GO:0002088//lens development in camera-type eye;GO:0061077//chaperone-mediated protein folding","K21991//protein unc-45","XP_537726.2//protein unc-45 homolog B [Canis lupus familiaris];NP_775259.1//protein unc-45 homolog B isoform 1 [Homo sapiens];NP_001295210.1//protein unc-45 homolog B isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[6507,3834,0.02,0.02,0,1.00941689355778,"*",0.998548,"SLC1A3","GO:0016020//membrane;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0043025//neuronal cell body;GO:0043005//neuron projection","GO:0005313//L-glutamate transmembrane transporter activity;GO:0016595//glutamate binding;GO:0046872//metal ion binding;GO:0015293//symporter activity;GO:0005314//high-affinity glutamate transmembrane transporter activity;GO:0015501//glutamate:sodium symporter activity;GO:0015171//amino acid transmembrane transporter activity","GO:0070779//D-aspartate import;GO:0009416//response to light stimulus;GO:0006537//glutamate biosynthetic process;GO:0046677//response to antibiotic;GO:0140009//L-aspartate import across plasma membrane;GO:0001504//neurotransmitter uptake;GO:1902476//chloride transmembrane transport;GO:0009611//response to wounding;GO:0042493//response to drug;GO:0089711//L-glutamate transmembrane transport;GO:0050806//positive regulation of synaptic transmission;GO:0009449//gamma-aminobutyric acid biosynthetic process;GO:0140016//D-aspartate import across plasma membrane;GO:0098712//L-glutamate import across plasma membrane;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0006811//ion transport;GO:0051938//L-glutamate import;GO:0031223//auditory behavior;GO:0007605//sensory perception of sound;GO:0021545//cranial nerve development;GO:0007268//chemical synaptic transmission;GO:0071805//potassium ion transmembrane transport;GO:0050885//neuromuscular process controlling balance;GO:0014047//glutamate secretion","K05614//solute carrier family 1 (glial high affinity glutamate transporter), member 3","NP_001276869.1//excitatory amino acid transporter 1 isoform 5 [Homo sapiens];NP_001160168.1//excitatory amino acid transporter 1 isoform 3 [Homo sapiens];NP_001160167.1//excitatory amino acid transporter 1 isoform 2 [Homo sapiens];NP_001276868.1//excitatory amino acid transporter 1 isoform 4 [Homo sapiens];NP_004163.3//excitatory amino acid transporter 1 isoform 1 [Homo sapiens]","1//3;4;2//1"]
[284467,1144,0.08,0.08,0,1.00922529275546,"*",0.998548,"FAM19A3","GO:0005615//extracellular space","NA","GO:1903979//negative regulation of microglial cell activation;GO:1903980//positive regulation of microglial cell activation","NA","XP_004026418.2//PREDICTED: protein FAM19A3 [Gorilla gorilla gorilla];NP_001004440.1//protein FAM19A3 isoform 2 precursor [Homo sapiens]","1//3;2//1"]
[10966,1776,5.08,5.08,0,1.01921565115228,"*",0.988398,"RAB40B","GO:0005635//nuclear envelope;GO:0005622//intracellular;GO:0048471//perinuclear region of cytoplasm","GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0016567//protein ubiquitination;GO:1990967//multi-organism toxin transport;GO:0035556//intracellular signal transduction","K07928//Ras-related protein Rab-40","BAD92948.1//RAB40B, member RAS oncogene family variant, partial [Homo sapiens]","2//1"]
[22917,1972,0.08,0.08,0,1.01334548560534,"*",0.998184,"ZP1","GO:0031012//extracellular matrix;GO:0030141//secretory granule;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005578//proteinaceous extracellular matrix","NA","GO:0007339//binding of sperm to zona pellucida","K19926//zona pellucida sperm-binding protein 1","NP_997224.2//zona pellucida sperm-binding protein 1 precursor [Homo sapiens]","3//A2MP1"]
[3263,1635,0.1,0.1,0,1.01328108896797,"*",0.998184,"HPX","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0072562//blood microparticle;GO:0005623//cell;GO:0005576//extracellular region;GO:0071682//endocytic vesicle lumen","GO:0015232//heme transporter activity;GO:0046872//metal ion binding","GO:0020027//hemoglobin metabolic process;GO:0006879//cellular iron ion homeostasis;GO:0060335//positive regulation of interferon-gamma-mediated signaling pathway;GO:0015886//heme transport;GO:0016032//viral process;GO:0002639//positive regulation of immunoglobulin production;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0006898//receptor-mediated endocytosis;GO:0042168//heme metabolic process;GO:0002925//positive regulation of humoral immune response mediated by circulating immunoglobulin","K18977//hemopexin","NP_000604.1//hemopexin precursor [Homo sapiens]","2//1"]
[1768,12795,0.01,0.01,0,0.652655736695595,"*",0.499032,"DNAH6","GO:0005929//cilium;GO:0005874//microtubule;GO:0030286//dynein complex;GO:0005737//cytoplasm;GO:0005858//axonemal dynein complex","GO:0051959//dynein light intermediate chain binding;GO:0045505//dynein intermediate chain binding;GO:0005524//ATP binding;GO:0045503//dynein light chain binding;GO:0008569//ATP-dependent microtubule motor activity, minus-end-directed","GO:0001539//cilium or flagellum-dependent cell motility;GO:0007018//microtubule-based movement;GO:0060271//cilium assembly","K10408//dynein heavy chain, axonemal","NP_001361.1//dynein heavy chain 6, axonemal [Homo sapiens]","1//3"]
[64753,3241,0.37,0.37,0,0.915152865787018,"*",0.859696,"CCDC136","NA","NA","NA","K20282//GRIP and coiled-coil domain-containing protein 2;K04437//filamin","XP_010377047.1//PREDICTED: coiled-coil domain-containing protein 136 isoform X1 [Rhinopithecus roxellana];XP_013974613.1//coiled-coil domain-containing protein 136 isoform X5 [Canis lupus familiaris]","1//3;4"]
[3662,5329,0.01,0.01,0,0.652281905572375,"*",0.499032,"IRF4","GO:0016020//membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0000788//nuclear nucleosome","GO:0016279//protein-lysine N-methyltransferase activity;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0008134//transcription factor binding;GO:0003700//DNA binding transcription factor activity","GO:0072540//T-helper 17 cell lineage commitment;GO:0060337//type I interferon signaling pathway;GO:0034122//negative regulation of toll-like receptor signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0043967//histone H4 acetylation;GO:0045622//regulation of T-helper cell differentiation;GO:0043388//positive regulation of DNA binding;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0042110//T cell activation;GO:0042832//defense response to protozoan;GO:0045404//positive regulation of interleukin-4 biosynthetic process;GO:0045082//positive regulation of interleukin-10 biosynthetic process;GO:0045368//positive regulation of interleukin-13 biosynthetic process;GO:0045086//positive regulation of interleukin-2 biosynthetic process;GO:0043966//histone H3 acetylation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0043011//myeloid dendritic cell differentiation","K09445//interferon regulatory factor 4","NP_001182215.1//interferon regulatory factor 4 isoform 2 [Homo sapiens];NP_002451.2//interferon regulatory factor 4 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[343,1315,0.06,0.06,0,1.0083958624352,"*",0.998548,"AQP8","GO:0005887//integral component of plasma membrane;GO:0045177//apical part of cell;GO:0005886//plasma membrane","GO:0015250//water channel activity","GO:0006833//water transport;GO:0006810//transport;GO:0034220//ion transmembrane transport;GO:0071320//cellular response to cAMP","K09869//aquaporin-8","NP_001160.2//aquaporin-8 [Homo sapiens]","2//1"]
[162333,3476,0.05,0.05,0,1.01289488095541,"*",0.998184,"2019-03-10","NA","GO:0008270//zinc ion binding","NA","K10665//E3 ubiquitin-protein ligase MARCH10 [EC:2.3.2.27]","XP_016788190.1//PREDICTED: probable E3 ubiquitin-protein ligase MARCH10 isoform X6 [Pan troglodytes];XP_003811371.1//PREDICTED: probable E3 ubiquitin-protein ligase MARCH10 isoform X1 [Pan paniscus];XP_001145535.2//PREDICTED: probable E3 ubiquitin-protein ligase MARCH10 isoform X1 [Pan troglodytes]","1//3;3//A2MP1;2//1"]
[9077,1984,0.04,0.04,0,1.00814092731639,"*",0.998548,"DIRAS3","GO:0016020//membrane;GO:0005622//intracellular;GO:0005886//plasma membrane","GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0007165//signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0006349//regulation of gene expression by genetic imprinting;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity","K07842//DIRAS family, GTP-binding Ras-like 3","NP_004666.1//GTP-binding protein Di-Ras3 precursor [Homo sapiens]","3//A2MP1"]
[401027,2259,0.11,0.11,0,1.01587961685042,"*",0.997882,"C2orf66","GO:0005576//extracellular region","NA","NA","NA","NP_998773.1//uncharacterized protein C2orf66 precursor [Homo sapiens]","2//1"]
[26018,4812,0.58,0.58,0,1.02193482413549,"*",0.993466,"LRIG1","GO:0016021//integral component of membrane","NA","GO:0060384//innervation;GO:0007605//sensory perception of sound;GO:0032474//otolith morphogenesis;GO:0022405//hair cycle process","K19511//peroxidase [EC:1.11.1.7]","XP_007983103.1//PREDICTED: leucine-rich repeats and immunoglobulin-like domains protein 1 isoform X1 [Chlorocebus sabaeus]","2//1"]
[8294,370,0.49,0.49,0,1.01263757246285,"*",0.998184,"HIST1H4I","GO:0005634//nucleus;GO:0000786//nucleosome","GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity","GO:0006334//nucleosome assembly;GO:0006352//DNA-templated transcription, initiation","K11253//histone H3;K11254//histone H4","XP_014590042.1//PREDICTED: histone H4 [Equus caballus]","2//1"]
[4284,2608,0.03,0.03,0,1.00756779432759,"*",0.998548,"MIP","GO:0005921//gap junction;GO:0005783//endoplasmic reticulum;GO:0005887//integral component of plasma membrane;GO:0016324//apical plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0015250//water channel activity;GO:0005212//structural constituent of eye lens;GO:0005516//calmodulin binding","GO:0006833//water transport;GO:1990349//gap junction-mediated intercellular transport;GO:0051289//protein homotetramerization;GO:0034220//ion transmembrane transport;GO:0050896//response to stimulus;GO:0045785//positive regulation of cell adhesion;GO:0007601//visual perception;GO:0002088//lens development in camera-type eye","K09863//aquaporin-0","NP_036196.1//lens fiber major intrinsic protein [Homo sapiens]","3//A2MP1"]
[55083,13593,0.01,0.01,0,1.00731327767603,"*",0.998548,"KIF26B","GO:0005874//microtubule;GO:0005737//cytoplasm;GO:0005871//kinesin complex","GO:0005524//ATP binding;GO:0003777//microtubule motor activity;GO:0008017//microtubule binding","GO:0030010//establishment of cell polarity;GO:0022409//positive regulation of cell-cell adhesion;GO:0072092//ureteric bud invasion","K10404//kinesin family member 26","NP_060482.2//kinesin-like protein KIF26B [Homo sapiens]",4]
[10396,8225,0.01,0.01,0,1.00693174370305,"*",0.998548,"ATP8A1","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0005783//endoplasmic reticulum;GO:0005802//trans-Golgi network;GO:0000139//Golgi membrane;GO:0035577//azurophil granule membrane;GO:0005794//Golgi apparatus;GO:0035579//specific granule membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0042584//chromaffin granule membrane","GO:0000287//magnesium ion binding;GO:0005524//ATP binding;GO:0019829//cation-transporting ATPase activity;GO:0004012//phospholipid-translocating ATPase activity","GO:0061092//positive regulation of phospholipid translocation;GO:0030335//positive regulation of cell migration;GO:0045332//phospholipid translocation;GO:0048194//Golgi vesicle budding;GO:0034220//ion transmembrane transport;GO:0043312//neutrophil degranulation;GO:0007612//learning","K14802//phospholipid-transporting ATPase [EC:3.6.3.1]","XP_016863134.1//PREDICTED: phospholipid-transporting ATPase IA isoform X5 [Homo sapiens];XP_005248100.1//PREDICTED: phospholipid-transporting ATPase IA isoform X3 [Homo sapiens]","1//3;2//1"]
[8787,2531,0.15,0.15,0,1.01562071156419,"*",0.997882,"RGS9","GO:0097381//photoreceptor disc membrane;GO:0005634//nucleus;GO:0001917//photoreceptor inner segment;GO:0005834//heterotrimeric G-protein complex;GO:0001750//photoreceptor outer segment;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0004871//signal transducer activity;GO:0032403//protein complex binding;GO:0005096//GTPase activator activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0006457//protein folding;GO:0007399//nervous system development;GO:0009968//negative regulation of signal transduction;GO:0007601//visual perception;GO:0035556//intracellular signal transduction;GO:0043627//response to estrogen;GO:0007212//dopamine receptor signaling pathway;GO:0008277//regulation of G-protein coupled receptor protein signaling pathway","K13765//regulator of G-protein signaling 9","NP_001075424.1//regulator of G-protein signaling 9 isoform 2 [Homo sapiens];NP_003826.2//regulator of G-protein signaling 9 isoform 1 [Homo sapiens];NP_001159405.1//regulator of G-protein signaling 9 isoform 3 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[79831,2481,1.26,1.26,0,1.02209722878681,"*",0.993112,"KDM8","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol","GO:0046872//metal ion binding;GO:0051864//histone demethylase activity (H3-K36 specific);GO:0003682//chromatin binding;GO:0032452//histone demethylase activity","GO:0006351//transcription, DNA-templated;GO:0070544//histone H3-K36 demethylation;GO:0000086//G2/M transition of mitotic cell cycle;GO:0045893//positive regulation of transcription, DNA-templated","K10277//lysine-specific demethylase 8 [EC:1.14.11.27]","NP_001138820.1//lysine-specific demethylase 8 isoform 1 [Homo sapiens]","1//3;2//1"]
[5455,4525,0.02,0.02,0,1.00642348110291,"*",0.998548,"POU3F3","GO:0005634//nucleus","GO:0071837//HMG box domain binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0021799//cerebral cortex radially oriented cell migration;GO:0072218//metanephric ascending thin limb development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0072236//metanephric loop of Henle development;GO:0072227//metanephric macula densa development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0021869//forebrain ventricular zone progenitor cell division;GO:0007588//excretion;GO:0006351//transcription, DNA-templated;GO:0043066//negative regulation of apoptotic process;GO:0007417//central nervous system development;GO:0010628//positive regulation of gene expression;GO:0072240//metanephric DCT cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0072233//metanephric thick ascending limb development;GO:0048878//chemical homeostasis;GO:0008284//positive regulation of cell proliferation","K09365//POU domain transcription factor, class 3","NP_006227.1//POU domain, class 3, transcription factor 3 [Homo sapiens]","2//1"]
[240,2420,0.1,0.1,0,1.01542661918716,"*",0.997882,"ALOX5","GO:0034774//secretory granule lumen;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0005615//extracellular space;GO:0005635//nuclear envelope;GO:0016363//nuclear matrix;GO:0005829//cytosol;GO:0005576//extracellular region;GO:1904813//ficolin-1-rich granule lumen;GO:0005641//nuclear envelope lumen","GO:0004051//arachidonate 5-lipoxygenase activity;GO:0005506//iron ion binding","GO:0002540//leukotriene production involved in inflammatory response;GO:0006691//leukotriene metabolic process;GO:2001300//lipoxin metabolic process;GO:0019372//lipoxygenase pathway;GO:0043312//neutrophil degranulation;GO:0019370//leukotriene biosynthetic process","K00461//arachidonate 5-lipoxygenase [EC:1.13.11.34]","NP_001243082.1//arachidonate 5-lipoxygenase isoform 2 [Homo sapiens];NP_000689.1//arachidonate 5-lipoxygenase isoform 1 [Homo sapiens];NP_001243083.1//arachidonate 5-lipoxygenase isoform 3 [Homo sapiens];NP_001307790.1//arachidonate 5-lipoxygenase isoform 4 [Homo sapiens]","4;1//3;2//1"]
[338645,5185,0.13,0.13,0,1.01961911065574,"*",0.996768,"LUZP2","NA","NA","NA","K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K02927//large subunit ribosomal protein L40e;K15696//RING finger protein 113B;K17985//activating molecule in BECN1-regulated autophagy protein 1;K12025//tripartite motif-containing protein 52","CAD90000.1//hypothetical protein, partial [Homo sapiens];XP_009458391.2//PREDICTED: leucine zipper protein 2 isoform X1 [Pan troglodytes];XP_011849319.1//PREDICTED: leucine zipper protein 2 isoform X2 [Mandrillus leucophaeus]","1//3;3//A2MP1"]
[140831,2831,0.56,0.56,0,1.02116809688403,"*",0.995022,"ZSWIM3","NA","GO:0008270//zinc ion binding","NA","K17604//zinc finger SWIM domain-containing protein 3","NP_542790.2//zinc finger SWIM domain-containing protein 3 [Homo sapiens]","3//A2MP1"]
[84303,1020,9.59,9.59,0,1.0189163883796,"*",0.988044,"CHCHD6","GO:0005829//cytosol;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0061617//MICOS complex","NA","GO:0042407//cristae formation;GO:0006974//cellular response to DNA damage stimulus","K17564//coiled-coil-helix-coiled-coil-helix domain-containing protein 6, mitochondrial","NP_115719.1//MICOS complex subunit MIC25 isoform 2 [Homo sapiens];NP_001307539.1//MICOS complex subunit MIC25 isoform 1 [Homo sapiens]","1//3;2//1"]
[1045,3513,0.18,0.18,0,1.01948854091433,"*",0.996768,"CDX2","GO:0017053//transcriptional repressor complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0043234//protein complex;GO:0000794//condensed nuclear chromosome","GO:0003714//transcription corepressor activity;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0001227//transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding","GO:0009952//anterior/posterior pattern specification;GO:0001829//trophectodermal cell differentiation;GO:0035019//somatic stem cell population maintenance;GO:0001568//blood vessel development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0060711//labyrinthine layer development;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0008333//endosome to lysosome transport;GO:0045597//positive regulation of cell differentiation;GO:0030154//cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0060575//intestinal epithelial cell differentiation;GO:0009887//animal organ morphogenesis;GO:0014807//regulation of somitogenesis;GO:0009948//anterior/posterior axis specification;GO:0045197//establishment or maintenance of epithelial cell apical/basal polarity;GO:0008284//positive regulation of cell proliferation","K22234//homeobox protein CDX2","NP_001256.3//homeobox protein CDX-2 isoform 1 [Homo sapiens];NP_001341629.1//homeobox protein CDX-2 isoform 2 [Homo sapiens]","1//3;5"]
[2049,4234,0.13,0.13,0,0.862596,"*",0.793368,"EPHB3","NA","NA","NA","K05112//Eph receptor B3 [EC:2.7.10.1]","XP_013369041.1//PREDICTED: ephrin type-B receptor 3 [Chinchilla lanigera]","3//A2MP1"]
[2705,1623,0.05,0.05,0,1.00566204854675,"*",0.998548,"GJB1","GO:0005922//connexin complex;GO:0016021//integral component of membrane;GO:0016328//lateral plasma membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005737//cytoplasm","GO:0005243//gap junction channel activity;GO:0042803//protein homodimerization activity","GO:0006810//transport;GO:0007399//nervous system development;GO:0007154//cell communication;GO:0007267//cell-cell signaling;GO:1905867//epididymis development;GO:0016264//gap junction assembly;GO:0015868//purine ribonucleotide transport;GO:0051259//protein oligomerization","K07620//gap junction beta-1 protein","OBS83720.1//hypothetical protein A6R68_22323 [Neotoma lepida];NP_000157.1//gap junction beta-1 protein [Homo sapiens]","2//1;5"]
[5324,6874,0.01,0.01,0,0.632705790006325,"*",0.500968,"PLAG1","GO:0005634//nucleus;GO:0016607//nuclear speck","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0060252//positive regulation of glial cell proliferation;GO:0006351//transcription, DNA-templated;GO:0010629//negative regulation of gene expression;GO:0010628//positive regulation of gene expression;GO:0035264//multicellular organism growth;GO:0006915//apoptotic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0060736//prostate gland growth;GO:0022612//gland morphogenesis","K19484//zinc finger protein PLAG1","BAD92368.1//Pleiomorphic adenoma gene 1 variant, partial [Homo sapiens];NP_002646.2//zinc finger protein PLAG1 isoform a [Homo sapiens]","1//3;2//1"]
[26531,2229,0.18,0.18,0,0.830727588125389,"*",0.751524,"OR11A1","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity","NA","K04257//olfactory receptor","NP_039225.1//olfactory receptor 11A1 [Homo sapiens]","3//A2MP1"]
[8547,1046,0.08,0.08,0,1.005218411394,"*",0.998548,"FCN3","NA","NA","NA","K10104//ficolin","XP_017390181.1//PREDICTED: ficolin-3 [Cebus capucinus imitator];XP_012606027.1//ficolin-3 isoform X2 [Microcebus murinus]","3//A2MP1;2//1"]
[763,1084,0.08,0.08,0,1.00515506660785,"*",0.998548,"CA5A","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0008270//zinc ion binding;GO:0004089//carbonate dehydratase activity","GO:0015701//bicarbonate transport;GO:0006730//one-carbon metabolic process","K01672//carbonic anhydrase [EC:4.2.1.1]","NP_001730.1//carbonic anhydrase 5A, mitochondrial precursor [Homo sapiens]","1//3"]
[1606,2648,3.82,3.82,0,0.954993518940883,"*",0.912188,"DGKA","GO:0016020//membrane;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0004143//diacylglycerol kinase activity;GO:0003951//NAD+ kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0005509//calcium ion binding;GO:0005543//phospholipid binding","GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0046486//glycerolipid metabolic process;GO:0030168//platelet activation;GO:0035556//intracellular signal transduction;GO:0046834//lipid phosphorylation;GO:0046339//diacylglycerol metabolic process;GO:0006654//phosphatidic acid biosynthetic process","K00901//diacylglycerol kinase (ATP) [EC:2.7.1.107]","XP_016778734.1//PREDICTED: diacylglycerol kinase alpha isoform X1 [Pan troglodytes];NP_001337964.1//diacylglycerol kinase alpha isoform b [Homo sapiens];XP_018893847.1//PREDICTED: diacylglycerol kinase alpha isoform X3 [Gorilla gorilla gorilla]","4;1//3;2//1"]
[4892,5424,0.01,0.01,0,1.00464859557851,"*",0.998548,"NRAP","NA","GO:0003779//actin binding;GO:0046872//metal ion binding","NA","K18267//nebulin","XP_008049334.1//nebulin-related-anchoring protein isoform X2 [Carlito syrichta];XP_006183562.1//PREDICTED: nebulin-related-anchoring protein isoform X1 [Camelus ferus];XP_014413711.1//PREDICTED: nebulin-related-anchoring protein isoform X2 [Camelus ferus];XP_010968128.1//PREDICTED: LOW QUALITY PROTEIN: nebulin-related-anchoring protein [Camelus bactrianus]","4;1//3;3//A2MP1"]
[221303,1050,0.23,0.23,0,1.01478018003565,"*",0.997882,"FAM162B","NA","NA","NA","K04622//G protein-coupled receptor family C group 6 member A","XP_003827624.1//PREDICTED: protein FAM162B isoform X2 [Pan paniscus]","2//1"]
[8747,2666,0.03,0.03,0,1.00420585192647,"*",0.998548,"ADAM21","GO:0030424//axon;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0043025//neuronal cell body","GO:0046872//metal ion binding;GO:0008237//metallopeptidase activity;GO:0004222//metalloendopeptidase activity","GO:0007338//single fertilization;GO:0007339//binding of sperm to zona pellucida","K08610//disintegrin and metalloproteinase domain-containing protein 21 [EC:3.4.24.-]","NP_003804.2//disintegrin and metalloproteinase domain-containing protein 21 preproprotein [Homo sapiens]","3//A2MP1"]
[1087,2379,0.03,0.03,0,1.00388984530178,"*",0.998548,"CEACAM7","GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0031225//anchored component of membrane","NA","GO:0006501//C-terminal protein lipidation","K06499//carcinoembryonic antigen-related cell adhesion molecule","NP_001278414.1//carcinoembryonic antigen-related cell adhesion molecule 7 preproprotein [Homo sapiens]","4;1//3"]
[6622,3214,0.13,0.13,0,1.01737651162197,"*",0.997378,"SNCA","GO:0016020//membrane;GO:0030424//axon;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0005938//cell cortex;GO:0030054//cell junction;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0045202//synapse","GO:0048487//beta-tubulin binding;GO:0042802//identical protein binding;GO:0005507//copper ion binding;GO:0005509//calcium ion binding;GO:0043014//alpha-tubulin binding;GO:1903136//cuprous ion binding;GO:0050544//arachidonic acid binding","GO:0048148//behavioral response to cocaine;GO:0034599//cellular response to oxidative stress;GO:0008344//adult locomotory behavior;GO:0014059//regulation of dopamine secretion;GO:0071280//cellular response to copper ion;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007568//aging","K04528//alpha-synuclein","NP_000336.1//alpha-synuclein isoform NACP140 [Homo sapiens];NP_009292.1//alpha-synuclein isoform NACP112 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[23768,8117,0.2,0.2,0,1.02130945928925,"*",0.994904,"FLRT2","GO:0070062//extracellular exosome;GO:0005925//focal adhesion;GO:0031090//organelle membrane;GO:0005737//cytoplasm;GO:0005578//proteinaceous extracellular matrix;GO:0043005//neuron projection;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0005789//endoplasmic reticulum membrane;GO:0045202//synapse;GO:0005886//plasma membrane","GO:0005057//signal transducer activity, downstream of receptor;GO:0004860//protein kinase inhibitor activity;GO:0030674//protein binding, bridging;GO:0045499//chemorepellent activity;GO:0005104//fibroblast growth factor receptor binding","GO:0071711//basement membrane organization;GO:0061343//cell adhesion involved in heart morphogenesis;GO:0046426//negative regulation of JAK-STAT cascade;GO:0051965//positive regulation of synapse assembly;GO:0003007//heart morphogenesis;GO:0006469//negative regulation of protein kinase activity;GO:2001222//regulation of neuron migration;GO:0019221//cytokine-mediated signaling pathway;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0007411//axon guidance","K16362//leucine-rich repeat transmembrane protein FLRT","NP_037363.1//leucine-rich repeat transmembrane protein FLRT2 precursor [Homo sapiens]","1//3;5"]
[4838,1876,0.09,0.09,0,1.01148130017762,"*",0.998184,"NODAL","GO:0005615//extracellular space","GO:0070698//type I activin receptor binding;GO:0008083//growth factor activity;GO:0005125//cytokine activity;GO:0005160//transforming growth factor beta receptor binding;GO:0016015//morphogen activity","GO:0002085//inhibition of neuroepithelial cell differentiation;GO:0001890//placenta development;GO:0060460//left lung morphogenesis;GO:1901383//negative regulation of chorionic trophoblast cell proliferation;GO:0007420//brain development;GO:0001842//neural fold formation;GO:0001892//embryonic placenta development;GO:2000036//regulation of stem cell population maintenance;GO:1901164//negative regulation of trophoblast cell migration;GO:0060766//negative regulation of androgen receptor signaling pathway;GO:0060802//epiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification;GO:0045766//positive regulation of angiogenesis;GO:0048468//cell development;GO:0042074//cell migration involved in gastrulation;GO:0001893//maternal placenta development;GO:1900164//nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry;GO:0010470//regulation of gastrulation;GO:0030509//BMP signaling pathway;GO:0019827//stem cell population maintenance;GO:0033505//floor plate morphogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0048327//axial mesodermal cell fate specification;GO:0060137//maternal process involved in parturition;GO:0010575//positive regulation of vascular endothelial growth factor production;GO:0048382//mesendoderm development;GO:1900224//positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry;GO:0022409//positive regulation of cell-cell adhesion;GO:0035987//endodermal cell differentiation;GO:0048546//digestive tract morphogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0001944//vasculature development;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0060136//embryonic process involved in female pregnancy;GO:0009880//embryonic pattern specification;GO:0001831//trophectodermal cellular morphogenesis;GO:0048859//formation of anatomical boundary;GO:0032927//positive regulation of activin receptor signaling pathway;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0001889//liver development;GO:0090010//transforming growth factor beta receptor signaling pathway involved in primitive streak formation;GO:0060391//positive regulation of SMAD protein import into nucleus;GO:0060395//SMAD protein signal transduction;GO:0001947//heart looping;GO:0010085//polarity specification of proximal/distal axis;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0010721//negative regulation of cell development;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0050679//positive regulation of epithelial cell proliferation","K04666//nodal","NP_060525.3//nodal homolog isoform 1 preproprotein [Homo sapiens]","1//3;4"]
[4318,2387,0.1,0.1,0,1.01458640875819,"*",0.997882,"MMP9","GO:1904724//tertiary granule lumen;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:1904813//ficolin-1-rich granule lumen;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix","GO:0004252//serine-type endopeptidase activity;GO:0004175//endopeptidase activity;GO:0008237//metallopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0005518//collagen binding;GO:0042802//identical protein binding;GO:0008270//zinc ion binding","GO:0030335//positive regulation of cell migration;GO:0034614//cellular response to reactive oxygen species;GO:0035987//endodermal cell differentiation;GO:0001503//ossification;GO:1904707//positive regulation of vascular smooth muscle cell proliferation;GO:0007566//embryo implantation;GO:0001934//positive regulation of protein phosphorylation;GO:0051549//positive regulation of keratinocyte migration;GO:0043312//neutrophil degranulation;GO:0030225//macrophage differentiation;GO:0045742//positive regulation of epidermal growth factor receptor signaling pathway;GO:0071276//cellular response to cadmium ion;GO:0043388//positive regulation of DNA binding;GO:0050900//leukocyte migration;GO:0048013//ephrin receptor signaling pathway;GO:2001268//negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:1900122//positive regulation of receptor binding;GO:0022617//extracellular matrix disassembly;GO:0006508//proteolysis;GO:2001258//negative regulation of cation channel activity;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0001501//skeletal system development;GO:0030574//collagen catabolic process","K01403//matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]","NP_004985.2//matrix metalloproteinase-9 preproprotein [Homo sapiens]","2//1"]
[79698,2482,0.39,0.39,0,1.02056760002566,"*",0.996098,"ZMAT4","GO:0005634//nucleus;GO:0005622//intracellular","GO:0003723//RNA binding;GO:0003677//DNA binding;GO:0002039//p53 binding;GO:0008270//zinc ion binding;GO:0003676//nucleic acid binding","GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator","K10137//zinc finger, matrin type 3","XP_017817459.1//zinc finger matrin-type protein 4 isoform X1 [Papio anubis];NP_001129203.1//zinc finger matrin-type protein 4 isoform b [Homo sapiens]","1//3;2//1"]
[2196,14565,0.02,0.02,0,1.01452183477597,"*",0.997882,"FAT2","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005913//cell-cell adherens junction;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005509//calcium ion binding","GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0010631//epithelial cell migration","K16506//protocadherin Fat 1/2/3","NP_001438.1//protocadherin Fat 2 precursor [Homo sapiens]","2//1"]
[57633,5976,0.01,0.01,0,0.628729009428033,"*",0.500968,"LRRN1","GO:0005615//extracellular space;GO:0016021//integral component of membrane;GO:0005578//proteinaceous extracellular matrix","NA","GO:0051965//positive regulation of synapse assembly","K12655//OTU domain-containing protein 5 [EC:3.4.19.12];K16351//netrin-G2 ligand","NP_065924.3//leucine-rich repeat neuronal protein 1 precursor [Homo sapiens]","6;1//3"]
[126432,3050,1.72,1.72,0,1.02098860901528,"*",0.99114,"RINL","GO:0001726//ruffle;GO:0031410//cytoplasmic vesicle;GO:0015629//actin cytoskeleton","GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity","GO:0006897//endocytosis;GO:0015031//protein transport","K17638//Ras and Rab interactor 1;K17985//activating molecule in BECN1-regulated autophagy protein 1","NP_001182762.1//ras and Rab interactor-like protein isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[55026,3276,0.05,0.05,0,1.01090415368034,"*",0.998184,"TMEM255A","GO:0016021//integral component of membrane","NA","NA","NA","EAX11888.1//family with sequence similarity 70, member A, isoform CRA_b [Homo sapiens];NP_001098015.1//transmembrane protein 255A isoform 3 [Homo sapiens];EAX11890.1//family with sequence similarity 70, member A, isoform CRA_d [Homo sapiens]","1//3;3//A2MP1"]
[56920,4975,0.05,0.05,0,1.01426362102316,"*",0.997882,"SEMA3G","GO:0070062//extracellular exosome;GO:0005615//extracellular space","GO:0005102//receptor binding;GO:0038191//neuropilin binding","GO:0030517//negative regulation of axon extension;GO:0050919//negative chemotaxis","K06840//semaphorin 3","XP_001172139.2//PREDICTED: semaphorin-3G isoform X2 [Pan troglodytes]","2//1"]
[10170,1589,0.71,0.71,0,1.02093777526792,"*",0.995948,"DHRS9","GO:0031090//organelle membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005789//endoplasmic reticulum membrane","GO:0004022//alcohol dehydrogenase (NAD) activity;GO:0004745//retinol dehydrogenase activity;GO:0047035//testosterone dehydrogenase (NAD+) activity;GO:0016854//racemase and epimerase activity","GO:0042904//9-cis-retinoic acid biosynthetic process;GO:0042448//progesterone metabolic process;GO:0008209//androgen metabolic process;GO:0042572//retinol metabolic process;GO:0030855//epithelial cell differentiation","K11149//dehydrogenase/reductase SDR family member 9 [EC:1.1.-.-]","NP_001276692.1//dehydrogenase/reductase SDR family member 9 isoform 2 [Homo sapiens]","1//3"]
[728586,928,0.09,0.09,0,1.00187210300861,"*",0.998548,"CCDC192","NA","NA","NA","K14000//ribosome-binding protein 1;K16307//serine/threonine-protein kinase MRCK [EC:2.7.11.1]","NP_001304867.1//coiled-coil domain-containing protein 192 [Homo sapiens]","1//3"]
[9901,8977,0.08,0.08,0,1.01969617678709,"*",0.996588,"SRGAP3","GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0048365//Rac GTPase binding;GO:0005096//GTPase activator activity","GO:0007165//signal transduction;GO:0030336//negative regulation of cell migration;GO:0051056//regulation of small GTPase mediated signal transduction","K07526//SLIT-ROBO Rho GTPase activating protein","NP_055665.1//SLIT-ROBO Rho GTPase-activating protein 3 isoform a [Homo sapiens];NP_001028289.1//SLIT-ROBO Rho GTPase-activating protein 3 isoform b [Homo sapiens]","3//A2MP1;2//1"]
[10817,2198,3.1,3.1,0,1.02008741810206,"*",0.989882,"FRS3","NA","NA","NA","K12461//fibroblast growth factor receptor substrate 2","XP_011842079.1//PREDICTED: fibroblast growth factor receptor substrate 3 isoform X1 [Mandrillus leucophaeus]",4]
[128864,586,0.15,0.15,0,1.00149467897281,"*",0.998548,"C20orf144","NA","NA","NA","NA","NP_543015.1//uncharacterized protein C20orf144 [Homo sapiens]","3//A2MP1"]
[92292,2099,0.04,0.04,0,1.00130607357188,"*",0.998548,"GLYATL1","GO:0005739//mitochondrion","GO:0047946//glutamine N-acyltransferase activity;GO:0047961//glycine N-acyltransferase activity","GO:0006541//glutamine metabolic process","K00628//glycine N-acyltransferase / glycine N-benzoyltransferase [EC:2.3.1.13 2.3.1.71]","NP_001207423.1//glycine N-acyltransferase-like protein 1 isoform 2 [Homo sapiens];NP_542392.2//glycine N-acyltransferase-like protein 1 isoform 1 [Homo sapiens]","4;1//3;2//1"]
[58529,1583,0.05,0.05,0,1.00105471017949,"*",0.998548,"MYOZ1","GO:0005634//nucleus;GO:0030018//Z disc;GO:0015629//actin cytoskeleton;GO:0031143//pseudopodium","GO:0003779//actin binding;GO:0051373//FATZ binding;GO:0031433//telethonin binding","GO:0030239//myofibril assembly","K07597//desmoglein 2;K13098//RNA-binding protein FUS","NP_067068.1//myozenin-1 [Homo sapiens]","3//A2MP1"]
[63976,8674,0.04,0.04,0,1.01658063179382,"*",0.997616,"PRDM16","GO:0017053//transcriptional repressor complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016235//aggresome","GO:0046872//metal ion binding;GO:0003713//transcription coactivator activity;GO:0043565//sequence-specific DNA binding;GO:0046332//SMAD binding;GO:0033613//activating transcription factor binding;GO:0018024//histone-lysine N-methyltransferase activity","GO:0045892//negative regulation of transcription, DNA-templated;GO:0050872//white fat cell differentiation;GO:0006351//transcription, DNA-templated;GO:0035019//somatic stem cell population maintenance;GO:0045893//positive regulation of transcription, DNA-templated;GO:0043586//tongue development;GO:0030853//negative regulation of granulocyte differentiation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0022008//neurogenesis;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0043457//regulation of cellular respiration;GO:0050873//brown fat cell differentiation;GO:0060021//palate development;GO:0090336//positive regulation of brown fat cell differentiation","K09228//KRAB domain-containing zinc finger protein;K20688//Rho guanine nucleotide exchange factor 16","NP_955533.2//PR domain zinc finger protein 16 isoform 2 [Homo sapiens];NP_071397.3//PR domain zinc finger protein 16 isoform 1 [Homo sapiens]","3//A2MP1;2//1"]
[10964,5910,0.01,0.01,0,0.625485605127403,"*",0.500968,"IFI44L","GO:0005737//cytoplasm","GO:0005525//GTP binding","GO:0051607//defense response to virus","NA","NP_006811.2//interferon-induced protein 44-like [Homo sapiens]","3//A2MP1"]
[79668,7125,0.15,0.15,0,1.02087226334702,"*",0.995948,"PARP8","GO:0005622//intracellular","GO:0003950//NAD+ ADP-ribosyltransferase activity","NA","K15258//poly [ADP-ribose] polymerase 6/8 [EC:2.4.2.30]","XP_004380507.1//PREDICTED: poly [ADP-ribose] polymerase 8 isoform X3 [Trichechus manatus latirostris];NP_001317957.1//poly [ADP-ribose] polymerase 8 isoform 3 [Homo sapiens];XP_004380505.1//PREDICTED: poly [ADP-ribose] polymerase 8 isoform X1 [Trichechus manatus latirostris];XP_016808811.1//PREDICTED: poly [ADP-ribose] polymerase 8 isoform X2 [Pan troglodytes]","1//3;3//A2MP1"]
[1369,1756,0.05,0.05,0,1.00067790163112,"*",0.998548,"CPN1","GO:0030141//secretory granule;GO:0005615//extracellular space;GO:0005794//Golgi apparatus;GO:0005576//extracellular region;GO:0097060//synaptic membrane;GO:0043025//neuronal cell body","GO:0004185//serine-type carboxypeptidase activity;GO:0008270//zinc ion binding;GO:0004181//metallocarboxypeptidase activity","GO:0010815//bradykinin catabolic process;GO:0030449//regulation of complement activation;GO:0051384//response to glucocorticoid;GO:0030070//insulin processing","K01292//carboxypeptidase N catalytic subunit [EC:3.4.17.3]","NP_001299.1//carboxypeptidase N catalytic chain precursor [Homo sapiens]","2//1"]
[100528064,787,1.95,0.01,-7.60733031374961,{"v":1.91034093567251e-05,"d":"1.91E-05"},"Down",{"v":3.8855e-06,"d":"3.89E-06"},"NEDD8-MDP1","GO:0070062//extracellular exosome","GO:0046872//metal ion binding;GO:0004725//protein tyrosine phosphatase activity","NA","K17619//magnesium-dependent phosphatase 1 [EC:3.1.3.48 3.1.3.-]","NP_001186752.1//NEDD8-MDP1 protein [Homo sapiens]","2//1"]
[333932,507,0.67,0.01,-6.06608919045777,0.227473240490241,"*",0.1254848,"HIST2H3A","NA","NA","NA","K11253//histone H3;K11254//histone H4","XP_008958403.1//PREDICTED: uncharacterized protein LOC100972611 [Pan paniscus]","2//1"]
[8367,377,0.48,0.01,-5.58496250072116,0.390246236383124,"*",0.250726,"HIST1H4E","NA","NA","NA","K11253//histone H3;K11254//histone H4","XP_003804484.2//PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein LOC100980546 [Pan paniscus]","3//A2MP1"]
[8332,470,0.37,0.01,-5.20945336562895,0.390970043342444,"*",0.250726,"HIST1H2AL","NA","NA","NA","K11251//histone H2A;K11254//histone H4","XP_011931511.1//PREDICTED: uncharacterized protein LOC105593202 [Cercocebus atys]","2//1"]
[54979,785,0.32,0.01,-5,0.226701447093418,"*",0.1254848,"HRASLS2","GO:0005829//cytosol;GO:0016021//integral component of membrane","GO:0016746//transferase activity, transferring acyl groups;GO:0016787//hydrolase activity","GO:0036152//phosphatidylethanolamine acyl-chain remodeling;GO:0016042//lipid catabolic process","K16817//HRAS-like suppressor 3 [EC:3.1.1.32 3.1.1.4]","NP_060348.1//HRAS-like suppressor 2 [Homo sapiens]","1//3"]
[727837,1347,0.26,0.01,-4.70043971814109,0.128568283583237,"*",0.0628032,"SSX2B","GO:0005634//nucleus","GO:0003714//transcription corepressor activity;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:1903507//negative regulation of nucleic acid-templated transcription","K15625//protein SSX2;K15624//protein SSX1","XP_011925496.1//PREDICTED: protein SSX2 isoform X2 [Cercocebus atys];NP_003138.3//protein SSX2 isoform a [Homo sapiens];XP_009437384.2//PREDICTED: protein SSX2 isoform X2 [Pan troglodytes]","1//3;2//1"]
[100129216,213,0.24,0.01,-4.58496250072116,1.00084899140797,"*",0.999032,"DEFB131B","GO:0005615//extracellular space;GO:0009986//cell surface;GO:0005576//extracellular region","NA","GO:0002741//positive regulation of cytokine secretion involved in immune response;GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0090026//positive regulation of monocyte chemotaxis;GO:0071223//cellular response to lipoteichoic acid;GO:0042742//defense response to bacterium;GO:0032722//positive regulation of chemokine production;GO:0045087//innate immune response","NA","NP_001229782.1//beta-defensin 131B precursor [Homo sapiens]","1//3"]
[65982,2605,0.21,0.01,-4.39231742277876,0.0208810918611987,"*",0.00787322,"ZSCAN18","GO:0005634//nucleus","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0006351//transcription, DNA-templated","K09230//SCAN domain-containing zinc finger protein","NP_001139014.1//zinc finger and SCAN domain-containing protein 18 isoform 1 [Homo sapiens];XP_016882658.1//PREDICTED: zinc finger and SCAN domain-containing protein 18 isoform X3 [Homo sapiens]","4;1//3"]
[1160,1486,0.2,0.01,-4.32192809488736,0.128469498885901,"*",0.0628032,"CKMT2","GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0004111//creatine kinase activity","GO:0006936//muscle contraction;GO:0006600//creatine metabolic process","K00933//creatine kinase [EC:2.7.3.2]","NP_001816.2//creatine kinase S-type, mitochondrial precursor [Homo sapiens]","1//3;2//1"]
[392138,933,0.18,0.01,-4.16992500144231,0.390741182829268,"*",0.250726,"OR2A25","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity","NA","K04257//olfactory receptor","XP_020145275.1//olfactory receptor 2A25 [Microcebus murinus]","1//3"]
[168002,2469,0.49,0.03,-4.02974734339405,0.000553788903790911,"Down",1.472356E-4,"DACT2","GO:0005739//mitochondrion;GO:0005737//cytoplasm","GO:0005080//protein kinase C binding;GO:0051018//protein kinase A binding;GO:0008134//transcription factor binding;GO:0070097//delta-catenin binding;GO:0008013//beta-catenin binding","GO:1900108//negative regulation of nodal signaling pathway;GO:0002244//hematopoietic progenitor cell differentiation;GO:0043588//skin development;GO:0007162//negative regulation of cell adhesion;GO:0003382//epithelial cell morphogenesis;GO:0030111//regulation of Wnt signaling pathway;GO:0072061//inner medullary collecting duct development","K22154//dapper","NP_999627.2//dapper homolog 2 isoform a [Homo sapiens];NP_001273280.1//dapper homolog 2 isoform c [Homo sapiens];XP_011533809.1//PREDICTED: dapper homolog 2 isoform X1 [Homo sapiens]","4;1//3"]
[3957,543,0.16,0.01,-4,0.641325759897419,"*",0.500968,"LGALS2","NA","GO:0030246//carbohydrate binding;GO:0016936//galactoside binding","NA","K10090//galectin-2","NP_006489.1//galectin-2 [Homo sapiens]","2//1"]
[101059918,5172,0.15,0.01,-3.90689059560852,0.00600851514018692,"*",0.00197212,"GOLGA8R","GO:0005794//Golgi apparatus","NA","NA","K20358//golgin subfamily A member 2","NP_001269413.1//golgin subfamily A member 8R [Homo sapiens]","1//3"]
[404203,610,0.14,0.01,-3.8073549220576,0.63968527833733,"*",0.500968,"SPINK6","GO:0005576//extracellular region","GO:0004867//serine-type endopeptidase inhibitor activity","GO:1900004//negative regulation of serine-type endopeptidase activity;GO:0070268//cornification","NA","NP_995313.2//serine protease inhibitor Kazal-type 6 precursor [Homo sapiens]","1//3;3//A2MP1"]
[100129396,1759,0.14,0.01,-3.8073549220576,0.391658236260512,"*",0.250726,"FAM106CP","NA","NA","NA","NA","NP_001335091.1//putative protein FAM106C [Homo sapiens]","1//3"]
[170685,1955,0.13,0.01,-3.70043971814109,0.227344243529545,"*",0.1254848,"NUDT10","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0052841//inositol bisdiphosphate tetrakisphosphate diphosphatase activity;GO:0050072//m7G(5')pppN diphosphatase activity;GO:0052844//inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity;GO:0034431//bis(5'-adenosyl)-hexaphosphatase activity;GO:0016787//hydrolase activity;GO:0008486//diphosphoinositol-polyphosphate diphosphatase activity;GO:0052842//inositol diphosphate pentakisphosphate diphosphatase activity;GO:0052843//inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity;GO:0052845//inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity;GO:0052848//inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity;GO:0052846//inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity;GO:0046872//metal ion binding;GO:0000298//endopolyphosphatase activity;GO:0034432//bis(5'-adenosyl)-pentaphosphatase activity;GO:0052847//inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity;GO:0052840//inositol diphosphate tetrakisphosphate diphosphatase activity","GO:0071543//diphosphoinositol polyphosphate metabolic process;GO:0043647//inositol phosphate metabolic process;GO:1901907//diadenosine pentaphosphate catabolic process;GO:1901911//adenosine 5'-(hexahydrogen pentaphosphate) catabolic process;GO:1901909//diadenosine hexaphosphate catabolic process","K07766//diphosphoinositol-polyphosphate diphosphatase [EC:3.6.1.52]","NP_694853.1//diphosphoinositol polyphosphate phosphohydrolase 3-alpha [Homo sapiens]","1//3;3//A2MP1"]
[26083,685,0.12,0.01,-3.58496250072116,0.640504468704978,"*",0.500968,"TBC1D29","NA","NA","NA","K20134//TBC1 domain family member 3","EAW51237.1//DKFZP434O047 protein, isoform CRA_a [Homo sapiens]","2//1"]
[8712,680,0.12,0.01,-3.58496250072116,0.631607169060773,"*",0.500968,"PAGE1","NA","NA","GO:0006968//cellular defense response","NA","NP_003776.2//P antigen family member 1 [Homo sapiens]","3//A2MP1"]
[2709,1376,0.12,0.01,-3.58496250072116,0.390056206077133,"*",0.250726,"GJB5","GO:0005922//connexin complex;GO:0016021//integral component of membrane","NA","GO:1905867//epididymis development;GO:0008544//epidermis development;GO:0060713//labyrinthine layer morphogenesis;GO:0007154//cell communication;GO:0060708//spongiotrophoblast differentiation;GO:0060707//trophoblast giant cell differentiation","K07624//gap junction beta-5 protein","NP_005259.1//gap junction beta-5 protein [Homo sapiens]","3//A2MP1"]
[4049,1423,0.11,0.01,-3.4594316186373,0.390931881307955,"*",0.250726,"LTA","GO:0016020//membrane;GO:0005615//extracellular space;GO:0005886//plasma membrane","GO:0005164//tumor necrosis factor receptor binding;GO:0005125//cytokine activity;GO:0005102//receptor binding","GO:0060252//positive regulation of glial cell proliferation;GO:0032496//response to lipopolysaccharide;GO:0043065//positive regulation of apoptotic process;GO:0006959//humoral immune response;GO:0007584//response to nutrient;GO:0050830//defense response to Gram-positive bacterium;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0032729//positive regulation of interferon-gamma production;GO:0042493//response to drug;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0048535//lymph node development;GO:0048147//negative regulation of fibroblast proliferation;GO:0006915//apoptotic process;GO:0001666//response to hypoxia;GO:0002876//positive regulation of chronic inflammatory response to antigenic stimulus;GO:0044130//negative regulation of growth of symbiont in host;GO:0002925//positive regulation of humoral immune response mediated by circulating immunoglobulin","K05468//lymphotoxin alpha (TNF superfamily, member 1)","NP_000586.2//lymphotoxin-alpha precursor [Homo sapiens]","3//A2MP1;2//1"]
[1117,1456,0.11,0.01,-3.4594316186373,0.390855579584269,"*",0.250726,"CHI3L2","GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0030246//carbohydrate binding;GO:0016787//hydrolase activity;GO:0008061//chitin binding","GO:0005975//carbohydrate metabolic process","K17523//chitinase-3-like protein 1/2","AAB04534.1//chitinase, partial [Homo sapiens];EAW56480.1//chitinase 3-like 2, isoform CRA_a [Homo sapiens]","1//3;2//1"]
[54511,2385,0.1,0.01,-3.32192809488736,0.227421624143408,"*",0.1254848,"HMGCLL1","GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005789//endoplasmic reticulum membrane;GO:0048471//perinuclear region of cytoplasm","GO:0046872//metal ion binding;GO:0004419//hydroxymethylglutaryl-CoA lyase activity","GO:0046951//ketone body biosynthetic process","K01640//hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4]","XP_016811172.1//PREDICTED: 3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic isoform X2 [Pan troglodytes];NP_001274682.1//3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic isoform e [Homo sapiens];NP_061909.2//3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic isoform a [Homo sapiens];NP_001274670.1//3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic isoform c [Homo sapiens];XP_004416094.2//PREDICTED: LOW QUALITY PROTEIN: 3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic [Odobenus rosmarus divergens]","1//3;2//1"]
[6123,1547,0.1,0.01,-3.32192809488736,0.390664955520874,"*",0.250726,"RPL3L","GO:0005840//ribosome;GO:0016020//membrane;GO:0022625//cytosolic large ribosomal subunit","GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome","GO:0006412//translation;GO:0000027//ribosomal large subunit assembly","K02925//large subunit ribosomal protein L3e","NP_005052.1//60S ribosomal protein L3-like [Homo sapiens]","2//1"]
[51237,845,0.1,0.01,-3.32192809488736,0.628087499568323,"*",0.500968,"MZB1","GO:0005788//endoplasmic reticulum lumen;GO:0034663//endoplasmic reticulum chaperone complex;GO:0005576//extracellular region;GO:0005737//cytoplasm","NA","GO:0030888//regulation of B cell proliferation;GO:0042127//regulation of cell proliferation;GO:0002642//positive regulation of immunoglobulin biosynthetic process;GO:2001274//negative regulation of glucose import in response to insulin stimulus;GO:0033622//integrin activation;GO:0008284//positive regulation of cell proliferation;GO:0006915//apoptotic process","K14611//solute carrier family 23 (nucleobase transporter), member 1/2;K15410//elongation factor 1-delta","XP_001172512.2//PREDICTED: marginal zone B- and B1-cell-specific protein [Pan troglodytes]","3//A2MP1"]
[55753,3292,0.19,0.02,-3.24792751344359,0.0299403102916931,"*",0.01182318,"OGDHL","NA","GO:0004591//oxoglutarate dehydrogenase (succinyl-transferring) activity;GO:0030976//thiamine pyrophosphate binding","GO:0006099//tricarboxylic acid cycle","K00164//2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]","XP_012891653.1//PREDICTED: 2-oxoglutarate dehydrogenase-like, mitochondrial isoform X3 [Dipodomys ordii];XP_005900672.1//PREDICTED: 2-oxoglutarate dehydrogenase-like, mitochondrial [Bos mutus];XP_014199185.1//PREDICTED: 2-oxoglutarate dehydrogenase-like, mitochondrial isoform X1 [Pan paniscus];NP_001334752.1//2-oxoglutarate dehydrogenase-like, mitochondrial isoform d [Homo sapiens]","1//3;2//1"]
[728591,1115,0.09,0.01,-3.16992500144231,0.632305849557522,"*",0.500968,"CCDC169","NA","NA","NA","K14000//ribosome-binding protein 1","XP_004054424.2//PREDICTED: coiled-coil domain-containing protein 169 isoform X1 [Gorilla gorilla gorilla];NP_001138456.1//coiled-coil domain-containing protein 169 isoform c [Homo sapiens];XP_004054425.1//PREDICTED: coiled-coil domain-containing protein 169 isoform X2 [Gorilla gorilla gorilla];NP_001185837.1//coiled-coil domain-containing protein 169 isoform e [Homo sapiens];NP_001138453.1//coiled-coil domain-containing protein 169 isoform a [Homo sapiens]","1//3;2//1"]
[441669,942,0.09,0.01,-3.16992500144231,0.63026406489722,"*",0.500968,"OR4Q3","NA","NA","NA","K04257//olfactory receptor","XP_009247105.1//PREDICTED: LOW QUALITY PROTEIN: olfactory receptor 4Q3 [Pongo abelii]","1//3"]
[441531,1678,0.09,0.01,-3.16992500144231,0.627348920664785,"*",0.500968,"PGAM4","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0097228//sperm principal piece","GO:0004619//phosphoglycerate mutase activity;GO:0016787//hydrolase activity;GO:0004082//bisphosphoglycerate mutase activity;GO:0046538//2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity","GO:0006094//gluconeogenesis;GO:1902093//positive regulation of flagellated sperm motility;GO:0006096//glycolytic process;GO:0043456//regulation of pentose-phosphate shunt","K01834//2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]","NP_001025062.1//phosphoglycerate mutase 4 [Homo sapiens]","2//1"]
[64919,7828,0.35,0.04,-3.12928301694497,{"v":6.57936267340591e-07,"d":"6.58E-07"},"Down",{"v":1.059354E-7,"d":"1.06E-07"},"BCL11B","GO:0005634//nucleus;GO:0043005//neuron projection","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0043565//sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0003676//nucleic acid binding","GO:0021773//striatal medium spiny neuron differentiation;GO:0010837//regulation of keratinocyte proliferation;GO:0033077//T cell differentiation in thymus;GO:0035701//hematopoietic stem cell migration;GO:0003334//keratinocyte development;GO:0022008//neurogenesis;GO:0021902//commitment of neuronal cell to specific neuron type in forebrain;GO:0019216//regulation of lipid metabolic process;GO:0008285//negative regulation of cell proliferation;GO:0097535//lymphoid lineage cell migration into thymus;GO:0046632//alpha-beta T cell differentiation;GO:0007165//signal transduction;GO:0003382//epithelial cell morphogenesis;GO:0048538//thymus development;GO:0043066//negative regulation of apoptotic process;GO:0045664//regulation of neuron differentiation;GO:0043368//positive T cell selection;GO:0042475//odontogenesis of dentin-containing tooth;GO:0071678//olfactory bulb axon guidance;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0031077//post-embryonic camera-type eye development;GO:0033153//T cell receptor V(D)J recombination","K22046//B-cell lymphoma/leukemia 11B","NP_612808.1//B-cell lymphoma/leukemia 11B isoform 1 [Homo sapiens];NP_001269166.1//B-cell lymphoma/leukemia 11B isoform 3 [Homo sapiens];NP_075049.1//B-cell lymphoma/leukemia 11B isoform 2 [Homo sapiens];NP_001269167.1//B-cell lymphoma/leukemia 11B isoform 4 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[56751,1907,0.08,0.01,-3,0.393350729129837,"*",0.250726,"BARHL1","GO:0005634//nucleus","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0001764//neuron migration;GO:0030901//midbrain development;GO:0006355//regulation of transcription, DNA-templated;GO:0007605//sensory perception of sound;GO:0043524//negative regulation of neuron apoptotic process","K09360//BarH-like","EDL08401.1//BarH-like 1 (Drosophila), isoform CRA_b, partial [Mus musculus]","3//A2MP1"]
[390882,1038,0.08,0.01,-3,0.635418678100683,"*",0.500968,"OR7G2","NA","NA","NA","K04257//olfactory receptor","XP_012364869.1//PREDICTED: LOW QUALITY PROTEIN: olfactory receptor 7G2-like [Nomascus leucogenys]","1//3"]
[359787,1079,0.08,0.01,-3,0.633306650205761,"*",0.500968,"DPPA3","GO:0005634//nucleus;GO:0001939//female pronucleus;GO:0001940//male pronucleus;GO:0005737//cytoplasm","GO:0035064//methylated histone binding","GO:1901536//negative regulation of DNA demethylation;GO:0040016//embryonic cleavage;GO:0044726//protection of DNA demethylation of female pronucleus;GO:0016569//covalent chromatin modification;GO:2000653//regulation of genetic imprinting","NA","NP_954980.1//developmental pluripotency-associated protein 3 [Homo sapiens]","3//A2MP1"]
[51127,1932,0.08,0.01,-3,0.391046389767624,"*",0.250726,"TRIM17","GO:0005622//intracellular","GO:0030674//protein binding, bridging;GO:0008270//zinc ion binding;GO:0004842//ubiquitin-protein transferase activity","GO:0032880//regulation of protein localization;GO:0051865//protein autoubiquitination;GO:0006914//autophagy","K12007//tripartite motif-containing protein 17 [EC:2.3.2.27]","NP_057186.1//E3 ubiquitin-protein ligase TRIM17 isoform 1 [Homo sapiens];NP_001128327.1//E3 ubiquitin-protein ligase TRIM17 isoform 3 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[106821730,3816,0.15,0.02,-2.90689059560852,0.141492115301778,"*",0.0707372,"BUB1B-PAK6","GO:0005634//nucleus;GO:0001650//fibrillar center;GO:0030054//cell junction;GO:0005737//cytoplasm","GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0048365//Rac GTPase binding;GO:0045296//cadherin binding","GO:0023014//signal transduction by protein phosphorylation;GO:0016477//cell migration;GO:0007346//regulation of mitotic cell cycle;GO:0030036//actin cytoskeleton organization;GO:0006355//regulation of transcription, DNA-templated;GO:0032147//activation of protein kinase activity;GO:0007612//learning;GO:0043408//regulation of MAPK cascade;GO:0006915//apoptotic process;GO:0007613//memory;GO:0007626//locomotory behavior;GO:0007266//Rho protein signal transduction;GO:0007010//cytoskeleton organization;GO:0031098//stress-activated protein kinase signaling cascade;GO:0042981//regulation of apoptotic process","K05735//p21-activated kinase 6 [EC:2.7.11.1]","NP_064553.1//serine/threonine-protein kinase PAK 6 isoform 1 [Homo sapiens]","2//1"]
[100131539,3441,0.07,0.01,-2.8073549220576,0.227524880272418,"*",0.1254848,"ZNF705E","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_004452775.1//PREDICTED: zinc finger protein 596-like isoform X1 [Dasypus novemcinctus]","1//3"]
[80217,5395,0.07,0.01,-2.8073549220576,0.0709073249541025,"*",0.031432,"CFAP43","GO:0042995//cell projection","NA","NA","K10388//plectin;K20478//golgin subfamily B member 1","NP_079421.5//cilia- and flagella-associated protein 43 [Homo sapiens]",6]
[7007,6468,0.07,0.01,-2.8073549220576,0.0384060076845484,"*",0.01573122,"TECTA","GO:0070062//extracellular exosome;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0031225//anchored component of membrane;GO:0005578//proteinaceous extracellular matrix","GO:0005201//extracellular matrix structural constituent","GO:0007160//cell-matrix adhesion;GO:0006501//C-terminal protein lipidation;GO:0007605//sensory perception of sound","K18273//alpha-tectorin","NP_005413.2//alpha-tectorin precursor [Homo sapiens]","2//1"]
[1823,4271,0.21,0.03,-2.8073549220576,0.00999284618504436,"*",0.00345502,"DSC1","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005921//gap junction;GO:0101003//ficolin-1-rich granule membrane;GO:0001533//cornified envelope;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0030057//desmosome","GO:0005509//calcium ion binding","GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0043312//neutrophil degranulation;GO:0031424//keratinization;GO:0070268//cornification","K07600//desmocollin 1","NP_077739.1//desmocollin-1 isoform Dsc1a preproprotein [Homo sapiens];NP_004939.1//desmocollin-1 isoform Dsc1b precursor [Homo sapiens]","3//A2MP1;2//1"]
[6662,3963,3.9,0.6,-2.70043971814109,{"v":1.94174356681614e-29,"d":"1.94E-29"},"Down",{"v":5.42142E-31,"d":"5.42E-31"},"SOX9","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0043234//protein complex;GO:0044798//nuclear transcription factor complex","GO:0001046//core promoter sequence-specific DNA binding;GO:0043425//bHLH transcription factor binding;GO:0003682//chromatin binding;GO:0001158//enhancer sequence-specific DNA binding;GO:0035326//enhancer binding;GO:0008013//beta-catenin binding","GO:0060532//bronchus cartilage development;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0001708//cell fate specification;GO:0001502//cartilage condensation;GO:0051216//cartilage development;GO:0060018//astrocyte fate commitment;GO:0019933//cAMP-mediated signaling","K18435//transcription factor SOX9 (SOX group E)","BAD90382.1//mKIAA4243 protein, partial [Mus musculus]","3//A2MP1"]
[56130,3061,0.37,0.06,-2.62449086490779,0.0071280456167979,"*",2.38018E-3,"PCDHB6","GO:0005887//integral component of plasma membrane","GO:0042802//identical protein binding;GO:0005509//calcium ion binding","GO:0007416//synapse assembly;GO:0009988//cell-cell recognition;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007268//chemical synaptic transmission","K16494//protocadherin beta","NP_001013027.1//protocadherin beta-6 precursor [Pan troglodytes];XP_012360027.1//PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein LOC100585730 [Nomascus leucogenys]","1//3;3//A2MP1"]
[33,2565,0.06,0.01,-2.58496250072116,0.393119073812328,"*",0.250726,"ACADL","GO:0005759//mitochondrial matrix;GO:0031966//mitochondrial membrane","GO:0004466//long-chain-acyl-CoA dehydrogenase activity;GO:0016401//palmitoyl-CoA oxidase activity;GO:0050660//flavin adenine dinucleotide binding;GO:0000062//fatty-acyl-CoA binding;GO:0003995//acyl-CoA dehydrogenase activity","GO:0001659//temperature homeostasis;GO:0033539//fatty acid beta-oxidation using acyl-CoA dehydrogenase;GO:0051289//protein homotetramerization;GO:0055114//oxidation-reduction process;GO:0046322//negative regulation of fatty acid oxidation;GO:0042758//long-chain fatty acid catabolic process;GO:0044242//cellular lipid catabolic process;GO:0006635//fatty acid beta-oxidation;GO:0090181//regulation of cholesterol metabolic process;GO:0045717//negative regulation of fatty acid biosynthetic process;GO:0042413//carnitine catabolic process;GO:0019254//carnitine metabolic process, CoA-linked","K00255//long-chain-acyl-CoA dehydrogenase [EC:1.3.8.8]","XP_516063.3//PREDICTED: long-chain specific acyl-CoA dehydrogenase, mitochondrial isoform X1 [Pan troglodytes]","3//A2MP1"]
[862,7284,0.06,0.01,-2.58496250072116,0.226668425931782,"*",0.1256368,"RUNX1T1","GO:0005654//nucleoplasm;GO:0016363//nuclear matrix","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0003700//DNA binding transcription factor activity","GO:0045892//negative regulation of transcription, DNA-templated;GO:0006091//generation of precursor metabolites and energy;GO:0006351//transcription, DNA-templated;GO:0045599//negative regulation of fat cell differentiation","K10053//runt-related transcription factor 1; translocated to, 1","XP_012605070.1//protein CBFA2T1 isoform X4 [Microcebus murinus];XP_011792448.1//PREDICTED: LOW QUALITY PROTEIN: protein CBFA2T1 [Colobus angolensis palliatus];XP_014315183.1//PREDICTED: protein CBFA2T1 isoform X1 [Myotis lucifugus];XP_008253946.1//PREDICTED: LOW QUALITY PROTEIN: protein CBFA2T1 [Oryctolagus cuniculus];XP_012373560.1//PREDICTED: protein CBFA2T1 isoform X1 [Dasypus novemcinctus];XP_016869419.1//PREDICTED: protein CBFA2T1 isoform X1 [Homo sapiens];XP_012373561.1//PREDICTED: protein CBFA2T1 isoform X3 [Dasypus novemcinctus]","1//3;3//A2MP1;2//1"]
[793,2551,0.06,0.01,-2.58496250072116,0.391849831131983,"*",0.250726,"CALB1","GO:0070062//extracellular exosome;GO:0030425//dendrite;GO:0030424//axon;GO:0005634//nucleus;GO:0043195//terminal bouton;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0005829//cytosol;GO:0043197//dendritic spine;GO:0045202//synapse","GO:0005499//vitamin D binding;GO:0005509//calcium ion binding;GO:0008270//zinc ion binding","GO:0099509//regulation of presynaptic cytosolic calcium ion concentration;GO:1900271//regulation of long-term synaptic potentiation;GO:0055074//calcium ion homeostasis;GO:0010842//retina layer formation;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0007616//long-term memory;GO:0071310//cellular response to organic substance;GO:0044267//cellular protein metabolic process;GO:0035502//metanephric part of ureteric bud development;GO:0007626//locomotory behavior;GO:0072205//metanephric collecting duct development;GO:0072221//metanephric distal convoluted tubule development;GO:0007614//short-term memory;GO:0072286//metanephric connecting tubule development","K14757//calbindin D28","NP_004920.1//calbindin [Homo sapiens]","3//A2MP1"]
[7078,5496,0.06,0.01,-2.58496250072116,0.357462188264059,"*",0.21966,"TIMP3","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix;GO:0005604//basement membrane","GO:0002020//protease binding;GO:0008191//metalloendopeptidase inhibitor activity;GO:0008270//zinc ion binding","GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:1903984//positive regulation of TRAIL-activated apoptotic signaling pathway;GO:0010033//response to organic substance;GO:0043086//negative regulation of catalytic activity;GO:0051045//negative regulation of membrane protein ectodomain proteolysis;GO:1904684//negative regulation of metalloendopeptidase activity;GO:0071310//cellular response to organic substance","K16866//metalloproteinase inhibitor 3","XP_003258172.1//PREDICTED: metalloproteinase inhibitor 3 isoform X1 [Nomascus leucogenys]",4]
[728747,3517,0.06,0.01,-2.58496250072116,0.390284264665757,"*",0.250726,"ANKRD20A4","GO:0005886//plasma membrane","NA","NA","K17299//POTE ankyrin domain family protein","NP_001092275.1//ankyrin repeat domain-containing protein 20A4 [Homo sapiens]","1//3"]
[786,1327,0.06,0.01,-2.58496250072116,0.625094737697235,"*",0.500968,"CACNG1","GO:0005886//plasma membrane;GO:0005891//voltage-gated calcium channel complex","GO:0005245//voltage-gated calcium channel activity","GO:0006810//transport;GO:0070296//sarcoplasmic reticulum calcium ion transport;GO:0061337//cardiac conduction;GO:0006936//muscle contraction","K04866//voltage-dependent calcium channel gamma-1","NP_000718.1//voltage-dependent calcium channel gamma-1 subunit [Homo sapiens]","3//A2MP1"]
[100533178,878,0.55,0.1,-2.4594316186373,0.226591649904031,"*",0.1256368,"PRORY","NA","NA","NA","NA","NP_001269400.1//proline-rich protein, Y-linked [Homo sapiens]","1//3"]
[374403,1752,0.26,0.05,-2.37851162325373,0.226847772487849,"*",0.1256368,"TBC1D10C","GO:0016020//membrane;GO:0012505//endomembrane system;GO:0101003//ficolin-1-rich granule membrane;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005886//plasma membrane;GO:0031527//filopodium membrane","GO:0017137//Rab GTPase binding;GO:0005096//GTPase activator activity","GO:0051534//negative regulation of NFAT protein import into nucleus;GO:0090630//activation of GTPase activity;GO:0042147//retrograde transport, endosome to Golgi;GO:0006886//intracellular protein transport;GO:0050869//negative regulation of B cell activation;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0043312//neutrophil degranulation;GO:0031338//regulation of vesicle fusion","K19944//TBC1 domain family member 10","NP_940919.1//carabin isoform 1 [Homo sapiens];XP_012351390.1//PREDICTED: carabin isoform X2 [Nomascus leucogenys]","1//3;3//A2MP1"]
[729747,1762,0.05,0.01,-2.32192809488736,0.64096618598318,"*",0.500968,"ZNF878","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_007993536.1//PREDICTED: zinc finger protein 433-like isoform X2 [Chlorocebus sabaeus]","2//1"]
[345630,1572,0.05,0.01,-2.32192809488736,0.637595636363636,"*",0.500968,"FBLL1","NA","NA","NA","K14563//rRNA 2'-O-methyltransferase fibrillarin [EC:2.1.1.-]","NP_001342203.1//rRNA/tRNA 2'-O-methyltransferase fibrillarin-like protein 1 [Homo sapiens]","1//3"]
[84660,3228,0.05,0.01,-2.32192809488736,0.392425742112483,"*",0.250726,"CCDC62","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0030331//estrogen receptor binding;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity","GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0071392//cellular response to estradiol stimulus","K16464//centrosomal protein CEP250;K20040//huntingtin-interacting protein 1-related protein;K12478//early endosome antigen 1","NP_958843.2//coiled-coil domain-containing protein 62 [Homo sapiens]",4]
[2900,3057,0.05,0.01,-2.32192809488736,0.392041613547377,"*",0.250726,"GRIK4","GO:0032983//kainate selective glutamate receptor complex;GO:0042734//presynaptic membrane;GO:0030054//cell junction;GO:0045211//postsynaptic membrane","GO:0004970//ionotropic glutamate receptor activity;GO:0005234//extracellularly glutamate-gated ion channel activity","NA","K05204//glutamate receptor, ionotropic kainate 4","XP_011782368.1//PREDICTED: glutamate receptor ionotropic, kainate 4 [Colobus angolensis palliatus];XP_853030.3//glutamate receptor ionotropic, kainate 4 [Canis lupus familiaris]","4;2//1"]
[6097,3084,0.05,0.01,-2.32192809488736,0.391581650762612,"*",0.250726,"RORC","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body","GO:0003707//steroid hormone receptor activity;GO:0098531//transcription factor activity, direct ligand regulated sequence-specific DNA binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:0004879//nuclear receptor activity;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0008270//zinc ion binding;GO:0008142//oxysterol binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0036315//cellular response to sterol;GO:0045893//positive regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0019218//regulation of steroid metabolic process;GO:0048541//Peyer's patch development;GO:0010906//regulation of glucose metabolic process;GO:0032922//circadian regulation of gene expression;GO:0007623//circadian rhythm;GO:0045598//regulation of fat cell differentiation;GO:0072539//T-helper 17 cell differentiation;GO:0006805//xenobiotic metabolic process;GO:0006351//transcription, DNA-templated;GO:0048535//lymph node development;GO:0060612//adipose tissue development;GO:0042093//T-helper cell differentiation;GO:0070244//negative regulation of thymocyte apoptotic process;GO:0042753//positive regulation of circadian rhythm;GO:0060850//regulation of transcription involved in cell fate commitment;GO:0006367//transcription initiation from RNA polymerase II promoter","K08534//RAR-related orphan receptor gamma","NP_001001523.1//nuclear receptor ROR-gamma isoform b [Homo sapiens];EAW53405.1//RAR-related orphan receptor C, isoform CRA_a [Homo sapiens]","1//3;3//A2MP1"]
[2047,4691,0.05,0.01,-2.32192809488736,0.227138152430595,"*",0.1254848,"EPHB1","GO:0070062//extracellular exosome;GO:0030424//axon;GO:0005783//endoplasmic reticulum;GO:0032433//filopodium tip;GO:0031901//early endosome membrane;GO:0005887//integral component of plasma membrane;GO:0045121//membrane raft;GO:0005829//cytosol","GO:0005524//ATP binding;GO:0008046//axon guidance receptor activity;GO:0005005//transmembrane-ephrin receptor activity;GO:0032403//protein complex binding","GO:0031290//retinal ganglion cell axon guidance;GO:0051965//positive regulation of synapse assembly;GO:0048593//camera-type eye morphogenesis;GO:0060997//dendritic spine morphogenesis;GO:0014719//skeletal muscle satellite cell activation;GO:0060326//cell chemotaxis;GO:0050965//detection of temperature stimulus involved in sensory perception of pain;GO:0021631//optic nerve morphogenesis;GO:0061351//neural precursor cell proliferation;GO:0001525//angiogenesis;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0031589//cell-substrate adhesion;GO:1902723//negative regulation of skeletal muscle satellite cell proliferation;GO:0046777//protein autophosphorylation;GO:0030010//establishment of cell polarity;GO:0021952//central nervous system projection neuron axonogenesis;GO:1902725//negative regulation of satellite cell differentiation;GO:1901214//regulation of neuron death;GO:0046328//regulation of JNK cascade","K05110//Eph receptor B1 [EC:2.7.10.1]","NP_001179758.2//ephrin type-B receptor 1 precursor [Bos taurus]",4]
[23566,1738,0.05,0.01,-2.32192809488736,0.628976093059813,"*",0.500968,"LPAR3","GO:0030424//axon;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0070915//lysophosphatidic acid receptor activity;GO:0008289//lipid binding;GO:0001965//G-protein alpha-subunit binding;GO:0005543//phospholipid binding;GO:0004930//G-protein coupled receptor activity","GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway;GO:0032060//bleb assembly;GO:0000187//activation of MAPK activity;GO:0007268//chemical synaptic transmission;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0048672//positive regulation of collateral sprouting;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0051928//positive regulation of calcium ion transport","K04294//lysophosphatidic acid receptor 3","NP_036284.1//lysophosphatidic acid receptor 3 [Homo sapiens]","2//1"]
[2078,4256,0.05,0.01,-2.32192809488736,0.390170202045787,"*",0.250726,"ERG","GO:0005634//nucleus;GO:0030529//intracellular ribonucleoprotein complex;GO:0005737//cytoplasm","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0043565//sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0004871//signal transducer activity;GO:0003700//DNA binding transcription factor activity","GO:0003197//endocardial cushion development;GO:0016477//cell migration;GO:0007165//signal transduction;GO:0030154//cell differentiation;GO:2000504//positive regulation of blood vessel remodeling;GO:0006468//protein phosphorylation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0007275//multicellular organism development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0003199//endocardial cushion to mesenchymal transition involved in heart valve formation","K09435//transcriptional regulator ERG","XP_017381745.1//PREDICTED: transcriptional regulator ERG isoform X2 [Cebus capucinus imitator];NP_001278320.1//transcriptional regulator ERG isoform 7 [Homo sapiens];NP_891548.1//transcriptional regulator ERG isoform 1 [Homo sapiens];NP_001129626.1//transcriptional regulator ERG isoform 3 [Homo sapiens];NP_004440.1//transcriptional regulator ERG isoform 2 [Homo sapiens];NP_001230361.1//transcriptional regulator ERG isoform 6 [Homo sapiens];NP_001317954.1//transcriptional regulator ERG isoform 8 [Homo sapiens]","4;1//3;3//A2MP1;2//1"]
[56141,5221,0.05,0.01,-2.32192809488736,0.226752737013575,"*",0.1254848,"PCDHA7","NA","NA","NA","K16493//protocadherin alpha","XP_012360377.1//PREDICTED: protocadherin alpha-7 isoform X13 [Nomascus leucogenys]","1//3;2//1"]
[148418,1418,0.29,0.06,-2.27301849440642,0.226438253774117,"*",0.1256368,"SAMD13","NA","NA","NA","K11458//polyhomeotic-like protein 3;K11457//polyhomeotic-like protein 2","XP_005542946.1//PREDICTED: sterile alpha motif domain-containing protein 13 isoform X3 [Macaca fascicularis];XP_005542945.1//PREDICTED: sterile alpha motif domain-containing protein 13 isoform X2 [Macaca fascicularis];XP_019269720.1//PREDICTED: sterile alpha motif domain-containing protein 13 [Panthera pardus]","1//3;2//1"]
[3975,3428,2.06,0.44,-2.22706890854592,{"v":3.49183858064516e-11,"d":"3.49E-11"},"Down",{"v":3.32046e-12,"d":"3.32E-12"},"LHX1","GO:0005634//nucleus;GO:0043234//protein complex;GO:0005622//intracellular","GO:0046872//metal ion binding;GO:0003714//transcription corepressor activity;GO:0001158//enhancer sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0072050//S-shaped body morphogenesis;GO:0060065//uterus development;GO:0001705//ectoderm formation;GO:0010842//retina layer formation;GO:0021937//cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation;GO:0060067//cervix development;GO:0072049//comma-shaped body morphogenesis;GO:0048793//pronephros development;GO:0035847//uterine epithelium development;GO:0021537//telencephalon development;GO:0009953//dorsal/ventral pattern formation;GO:0048703//embryonic viscerocranium morphogenesis;GO:0060322//head development;GO:2000768//positive regulation of nephron tubule epithelial cell differentiation;GO:0061205//paramesonephric duct development;GO:0010468//regulation of gene expression;GO:0060429//epithelium development;GO:0032525//somite rostral/caudal axis specification;GO:0097477//lateral motor column neuron migration;GO:0060068//vagina development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0035502//metanephric part of ureteric bud development;GO:0090009//primitive streak formation;GO:0060066//oviduct development;GO:0021549//cerebellum development;GO:0001655//urogenital system development;GO:0007267//cell-cell signaling;GO:0021871//forebrain regionalization;GO:0009887//animal organ morphogenesis;GO:0040019//positive regulation of embryonic development;GO:0035852//horizontal cell localization;GO:0021527//spinal cord association neuron differentiation;GO:0035849//nephric duct elongation;GO:0007389//pattern specification process;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0009791//post-embryonic development;GO:0072177//mesonephric duct development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0009653//anatomical structure morphogenesis;GO:0001702//gastrulation with mouth forming second;GO:0008045//motor neuron axon guidance;GO:0072278//metanephric comma-shaped body morphogenesis;GO:0090190//positive regulation of branching involved in ureteric bud morphogenesis;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0072283//metanephric renal vesicle morphogenesis;GO:0072178//nephric duct morphogenesis;GO:0009952//anterior/posterior pattern specification;GO:0001822//kidney development;GO:0006355//regulation of transcription, DNA-templated;GO:0001706//endoderm formation;GO:2000744//positive regulation of anterior head development;GO:0009880//embryonic pattern specification;GO:0072077//renal vesicle morphogenesis;GO:0035846//oviduct epithelium development;GO:0072224//metanephric glomerulus development;GO:2000543//positive regulation of gastrulation;GO:0072284//metanephric S-shaped body morphogenesis;GO:0021517//ventral spinal cord development;GO:0060059//embryonic retina morphogenesis in camera-type eye;GO:0006366//transcription from RNA polymerase II promoter;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0021702//cerebellar Purkinje cell differentiation;GO:0009948//anterior/posterior axis specification;GO:0001657//ureteric bud development","K09372//LIM homeobox protein 1","NP_005559.2//LIM/homeobox protein Lhx1 [Homo sapiens]",4]
[25790,1836,0.18,0.04,-2.16992500144231,0.35786321672616,"*",0.21966,"CFAP45","GO:0005929//cilium;GO:0005634//nucleus;GO:0005654//nucleoplasm","NA","NA","K12484//Rab11 family-interacting protein 1/2/5;K12875//apoptotic chromatin condensation inducer in the nucleus;K18626//trichohyalin","NP_036469.2//cilia- and flagella-associated protein 45 [Homo sapiens]","2//1"]
[286436,1893,0.17,0.04,-2.08746284125034,0.357680819571865,"*",0.21966,"H2BFM","GO:0005634//nucleus;GO:0000786//nucleosome","GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity","GO:0006334//nucleosome assembly","K11252//histone H2B","NP_001157888.1//histone H2B type F-M [Homo sapiens]","1//3"]
[116969,1484,0.21,0.05,-2.0703893278914,0.357535035663338,"*",0.21966,"ART5","GO:0016020//membrane;GO:0005576//extracellular region","GO:0003953//NAD+ nucleosidase activity;GO:0003950//NAD+ ADP-ribosyltransferase activity;GO:0003956//NAD(P)+-protein-arginine ADP-ribosyltransferase activity","GO:0006471//protein ADP-ribosylation","K19977//ADP-ribosyltransferase 5 [EC:2.4.2.31]","XP_015290901.1//PREDICTED: ecto-ADP-ribosyltransferase 5 isoform X18 [Macaca fascicularis];XP_001157391.2//PREDICTED: ecto-ADP-ribosyltransferase 5 isoform X3 [Pan troglodytes];XP_008018169.1//PREDICTED: ecto-ADP-ribosyltransferase 5 isoform X2 [Chlorocebus sabaeus]","4;1//3"]
[646960,2158,0.04,0.01,-2,0.641017528997116,"*",0.500968,"PRSS56","GO:0005783//endoplasmic reticulum","GO:0004252//serine-type endopeptidase activity","GO:0006508//proteolysis;GO:0043010//camera-type eye development","K09640//transmembrane protease serine 9 [EC:3.4.21.-]","NP_001182058.1//serine protease 56 precursor [Homo sapiens]","1//3"]
[27283,1804,0.04,0.01,-2,0.639378621923937,"*",0.500968,"TINAG","GO:0043231//intracellular membrane-bounded organelle;GO:0005615//extracellular space;GO:0005604//basement membrane","GO:0008234//cysteine-type peptidase activity;GO:0005044//scavenger receptor activity;GO:0030247//polysaccharide binding;GO:0000166//nucleotide binding;GO:0004197//cysteine-type endopeptidase activity","GO:0007155//cell adhesion;GO:0006955//immune response","K01363//cathepsin B [EC:3.4.22.1]","NP_055279.3//tubulointerstitial nephritis antigen [Homo sapiens]","3//A2MP1"]
[100505679,498,1.4,0.35,-2,0.133131885772101,"*",0.0658992,"UBE2Q2L","NA","NA","NA","K10582//ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]","NP_001230460.1//putative ubiquitin-conjugating enzyme E2Q2-like protein [Homo sapiens]","1//3"]
[3766,5323,0.04,0.01,-2,0.392618088814822,"*",0.250726,"KCNJ10","NA","NA","NA","K05003//potassium inwardly-rectifying channel subfamily J member 10","XP_007974716.1//PREDICTED: ATP-sensitive inward rectifier potassium channel 10 isoform X1 [Chlorocebus sabaeus]",4]
[54346,2006,0.04,0.01,-2,0.635317785963798,"*",0.500968,"UNC93A","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","NA","NA","K16600//tubulin polyglutamylase TTLL2 [EC:6.-.-.-]","NP_061847.2//protein unc-93 homolog A isoform 1 [Homo sapiens];NP_001137419.1//protein unc-93 homolog A isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[5652,1889,0.04,0.01,-2,0.634612437113402,"*",0.500968,"PRSS8","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0046658//anchored component of plasma membrane;GO:0005886//plasma membrane;GO:0019897//extrinsic component of plasma membrane","GO:0004252//serine-type endopeptidase activity;GO:0004175//endopeptidase activity;GO:0017080//sodium channel regulator activity;GO:0008236//serine-type peptidase activity","GO:0010765//positive regulation of sodium ion transport;GO:0070268//cornification","K08664//prostasin [EC:3.4.21.-];K09630//polyserase 2 [EC:3.4.21.-]","NP_002764.1//prostasin preproprotein [Homo sapiens]",4]
[93979,1884,0.04,0.01,-2,0.632255892549577,"*",0.500968,"CPA5","NA","NA","NA","K08781//carboxypeptidase A5 [EC:3.4.17.1]","XP_018886130.1//PREDICTED: carboxypeptidase A5 [Gorilla gorilla gorilla];XP_009452329.1//PREDICTED: carboxypeptidase A5 isoform X2 [Pan troglodytes]","4;1//3"]
[1549,2128,0.04,0.01,-2,0.630661425801876,"*",0.500968,"CYP2A7","NA","GO:0020037//heme binding;GO:0005506//iron ion binding;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen","NA","K17684//cytochrome P450 family 2 subfamily A polypeptide 7 [EC:1.14.14.1];K17685//cytochrome P450 family 2 subfamily A polypeptide 13 [EC:1.14.14.1]","XP_016802409.1//PREDICTED: cytochrome P450 2A7 [Pan troglodytes];XP_011807890.1//PREDICTED: cytochrome P450 2A13-like isoform X2 [Colobus angolensis palliatus]","2//1"]
[259236,1861,0.04,0.01,-2,0.629867204407713,"*",0.500968,"TMIE","GO:0016021//integral component of membrane","NA","GO:0042472//inner ear morphogenesis;GO:0007605//sensory perception of sound","NA","XP_009237377.1//PREDICTED: LOW QUALITY PROTEIN: transmembrane inner ear expressed protein [Pongo abelii]","2//1"]
[7166,1815,0.04,0.01,-2,0.628482119846069,"*",0.500968,"TPH1","NA","NA","NA","K00502//tryptophan 5-monooxygenase [EC:1.14.16.4]","XP_008969740.1//PREDICTED: tryptophan 5-hydroxylase 1 [Pan paniscus]","2//1"]
[10655,2503,0.04,0.01,-2,0.627103113549095,"*",0.500968,"DMRT2","GO:0005634//nucleus;GO:0016021//integral component of membrane","GO:0046872//metal ion binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0042803//protein homodimerization activity","GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:2000287//positive regulation of myotome development;GO:0014807//regulation of somitogenesis;GO:0048706//embryonic skeletal system development;GO:0006351//transcription, DNA-templated","K19489//doublesex- and mab-3-related transcription factor 2","NP_870987.2//doublesex- and mab-3-related transcription factor 2 isoform 2 [Homo sapiens];AAF86295.1//DMRT2/terra-like protein [Homo sapiens]","6;4;2//1"]
[122618,1998,0.04,0.01,-2,0.625290110329739,"*",0.500968,"PLD4","GO:0045335//phagocytic vesicle;GO:0032588//trans-Golgi network membrane;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0004630//phospholipase D activity;GO:0004435//phosphatidylinositol phospholipase C activity;GO:0003824//catalytic activity;GO:0070290//N-acylphosphatidylethanolamine-specific phospholipase D activity","GO:0002244//hematopoietic progenitor cell differentiation;GO:0016042//lipid catabolic process;GO:0043647//inositol phosphate metabolic process;GO:0006909//phagocytosis","K16860//phospholipase D3/4 [EC:3.1.4.4]","NP_001295103.1//phospholipase D4 isoform 1 [Homo sapiens];XP_003807044.1//PREDICTED: phospholipase D4 [Pan paniscus]","1//3;3//A2MP1"]
[284071,4688,2.36,0.62,-1.92844673897497,{"v":2.5223598e-14,"d":"2.52E-14"},"Down",{"v":1.856952E-15,"d":"1.86E-15"},"MEIOC","GO:0005634//nucleus;GO:0005737//cytoplasm","NA","GO:0048599//oocyte development;GO:0007141//male meiosis I;GO:0007286//spermatid development;GO:0007144//female meiosis I;GO:0007130//synaptonemal complex assembly;GO:0006302//double-strand break repair;GO:0070192//chromosome organization involved in meiotic cell cycle;GO:0051729//germline cell cycle switching, mitotic to meiotic cell cycle;GO:0051310//metaphase plate congression;GO:0048255//mRNA stabilization","NA","NP_001138552.2//meiosis-specific coiled-coil domain-containing protein MEIOC [Homo sapiens]","2//1"]
[347517,1077,0.3,0.08,-1.90689059560852,0.35797274433789,"*",0.21966,"RAB41","GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0000139//Golgi membrane","GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0042147//retrograde transport, endosome to Golgi;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0006891//intra-Golgi vesicle-mediated transport","K07896//Ras-related protein Rab-41","NP_001027898.2//ras-related protein Rab-41 [Homo sapiens]","2//1"]
[29841,3610,0.26,0.07,-1.89308479608349,0.0506537991735537,"*",0.0214868,"GRHL1","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0031490//chromatin DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0044212//transcription regulatory region DNA binding","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0045616//regulation of keratinocyte differentiation;GO:0008544//epidermis development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0061436//establishment of skin barrier;GO:0019216//regulation of lipid metabolic process;GO:0002934//desmosome organization","K09275//transcription factor CP2 and related proteins","NP_937825.2//grainyhead-like protein 1 homolog [Homo sapiens]","2//1"]
[1945,1257,7.37,2.04,-1.85309546712357,{"v":2.53817388407728e-11,"d":"2.54E-11"},"Down",{"v":2.385E-12,"d":"2.39E-12"},"EFNA4","GO:0005887//integral component of plasma membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0031225//anchored component of membrane","GO:0046875//ephrin receptor binding;GO:0005005//transmembrane-ephrin receptor activity","GO:0030316//osteoclast differentiation;GO:0048013//ephrin receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0046849//bone remodeling;GO:0007411//axon guidance","K05462//ephrin-A","XP_009180736.1//ephrin-A4 isoform X1 [Papio anubis];NP_872631.1//ephrin-A4 isoform b precursor [Homo sapiens];XP_017723265.1//PREDICTED: ephrin-A4 isoform X2 [Rhinopithecus bieti]","1//3;2//1"]
[196993,1842,0.61,0.17,-1.84327449631255,0.0463234554231975,"*",0.01942662,"CT62","NA","NA","NA","NA","NP_001096128.1//cancer/testis antigen 62 [Homo sapiens]","1//3"]
[554250,1773,0.42,0.12,-1.8073549220576,0.0852927814911438,"*",0.0388874,"GDF5OS","GO:0005615//extracellular space;GO:0005622//intracellular;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0008083//growth factor activity;GO:0005125//cytokine activity;GO:0042802//identical protein binding;GO:0005160//transforming growth factor beta receptor binding;GO:0036122//BMP binding","GO:0045666//positive regulation of neuron differentiation;GO:0040014//regulation of multicellular organism growth;GO:0035137//hindlimb morphogenesis;GO:0007184//SMAD protein import into nucleus;GO:0030513//positive regulation of BMP signaling pathway;GO:0032332//positive regulation of chondrocyte differentiation;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:2001054//negative regulation of mesenchymal cell apoptotic process;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0048468//cell development;GO:0009612//response to mechanical stimulus;GO:0007267//cell-cell signaling;GO:0043524//negative regulation of neuron apoptotic process;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0043408//regulation of MAPK cascade;GO:0030326//embryonic limb morphogenesis;GO:0060395//SMAD protein signal transduction;GO:0035136//forelimb morphogenesis;GO:0032331//negative regulation of chondrocyte differentiation;GO:0002062//chondrocyte differentiation;GO:0043932//ossification involved in bone remodeling;GO:0050680//negative regulation of epithelial cell proliferation;GO:0042981//regulation of apoptotic process;GO:0060591//chondroblast differentiation","K04664//growth differentiation factor 5","XP_018872428.1//PREDICTED: growth/differentiation factor 5 [Gorilla gorilla gorilla]","1//3"]
[51666,3824,1.02,0.3,-1.76553474636298,{"v":3.68437523837209e-05,"d":"3.68E-05"},"Down",{"v":7.9343e-06,"d":"7.93E-06"},"ASB4","GO:0005634//nucleus;GO:0031462//Cul2-RING ubiquitin ligase complex;GO:0000151//ubiquitin ligase complex;GO:0005829//cytosol;GO:0031466//Cul5-RING ubiquitin ligase complex;GO:0005737//cytoplasm","GO:0061630//ubiquitin protein ligase activity;GO:0031625//ubiquitin protein ligase binding;GO:0004842//ubiquitin-protein transferase activity","GO:0043687//post-translational protein modification;GO:2001214//positive regulation of vasculogenesis;GO:0016567//protein ubiquitination;GO:0051865//protein autoubiquitination;GO:0035556//intracellular signal transduction","K10326//ankyrin repeat and SOCS box protein 4","NP_665879.1//ankyrin repeat and SOCS box protein 4 isoform b [Homo sapiens];NP_057200.1//ankyrin repeat and SOCS box protein 4 isoform a [Homo sapiens]","2//1"]
[7539,2906,0.47,0.14,-1.74723392962003,0.0275959952359551,"*",0.01076268,"ZFP37","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_015986052.1//PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 37 homolog [Rousettus aegyptiacus]","1//3;2//1"]
[1562,2385,0.1,0.03,-1.73696559416621,0.530884318727915,"*",0.376212,"CYP2C18","GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0005789//endoplasmic reticulum membrane","GO:0008395//steroid hydroxylase activity;GO:0020037//heme binding;GO:0005506//iron ion binding;GO:0019825//oxygen binding;GO:0008392//arachidonic acid epoxygenase activity;GO:0034875//caffeine oxidase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0008144//drug binding;GO:0070330//aromatase activity;GO:0004497//monooxygenase activity","GO:0008202//steroid metabolic process;GO:0042738//exogenous drug catabolic process;GO:0019627//urea metabolic process;GO:0070989//oxidative demethylation;GO:0016098//monoterpenoid metabolic process;GO:0006805//xenobiotic metabolic process;GO:0019373//epoxygenase P450 pathway","K07413//cytochrome P450 family 2 subfamily C [EC:1.14.14.1];K17721//cytochrome P450 family 2 subfamily C polypeptide 19 [EC:1.14.14.51 1.14.14.52 1.14.14.53 1.14.14.-];K17720//cytochrome P450 family 2 subfamily C polypeptide 18 [EC:1.14.14.1];K17719//cytochrome P450 family 2 subfamily C polypeptide 9 [EC:1.14.14.51 1.14.14.52 1.14.14.53 1.14.14.-]","NP_001122397.1//cytochrome P450 2C18 isoform 2 precursor [Homo sapiens];XP_003783775.1//PREDICTED: cytochrome P450 2C19 [Otolemur garnettii]","1//3;2//1"]
[9848,6356,1.03,0.31,-1.73230421679634,{"v":1.93862471204189e-08,"d":"1.94E-08"},"Down",{"v":2.5498E-9,"d":"2.55E-09"},"MFAP3L","GO:0005634//nucleus;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm","NA","NA","K17341//hemicentin","XP_005263423.1//PREDICTED: microfi brillar-associated protein 3-like isoform X1 [Homo sapiens];XP_016864353.1//PREDICTED: microfi brillar-associated protein 3-like isoform X2 [Homo sapiens]","1//3;3//A2MP1;7"]
[912,3795,0.13,0.04,-1.70043971814109,0.141403583131022,"*",0.0707372,"CD1D","GO:0005765//lysosomal membrane;GO:0010008//endosome membrane;GO:0016323//basolateral plasma membrane;GO:0005783//endoplasmic reticulum;GO:0005737//cytoplasm;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane","GO:0042393//histone binding;GO:0030884//exogenous lipid antigen binding;GO:0050839//cell adhesion molecule binding;GO:0071723//lipopeptide binding;GO:0030883//endogenous lipid antigen binding;GO:0030881//beta-2-microglobulin binding;GO:0004872//receptor activity;GO:0030882//lipid antigen binding","GO:0045089//positive regulation of innate immune response;GO:0042102//positive regulation of T cell proliferation;GO:0016032//viral process;GO:0048007//antigen processing and presentation, exogenous lipid antigen via MHC class Ib;GO:0045058//T cell selection;GO:0016045//detection of bacterium;GO:0048006//antigen processing and presentation, endogenous lipid antigen via MHC class Ib;GO:0034113//heterotypic cell-cell adhesion;GO:0045087//innate immune response;GO:0050776//regulation of immune response","K06448//T-cell surface glycoprotein CD1","NP_001757.1//antigen-presenting glycoprotein CD1d isoform 1 precursor [Homo sapiens];NP_001306074.1//antigen-presenting glycoprotein CD1d isoform 2 precursor [Homo sapiens]","1//3;3//A2MP1"]
[53826,1804,0.13,0.04,-1.70043971814109,0.530368942546995,"*",0.376212,"FXYD6","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005216//ion channel activity;GO:0017080//sodium channel regulator activity","GO:1903779//regulation of cardiac conduction;GO:2000649//regulation of sodium ion transmembrane transporter activity;GO:0034220//ion transmembrane transport","K13363//FXYD domain-containing ion transport regulator 6","XP_011782242.1//PREDICTED: FXYD domain-containing ion transport regulator 6 isoform X2 [Colobus angolensis palliatus];XP_012351380.1//PREDICTED: FXYD domain-containing ion transport regulator 6 isoform X1 [Nomascus leucogenys];XP_014202520.1//PREDICTED: FXYD domain-containing ion transport regulator 6 isoform X1 [Pan paniscus]","3//A2MP1;2//1"]
[2567,1512,0.16,0.05,-1.67807190511264,0.531259767326733,"*",0.376212,"GABRG3","GO:0030054//cell junction;GO:0034707//chloride channel complex;GO:0005886//plasma membrane;GO:0045211//postsynaptic membrane","GO:0005230//extracellular ligand-gated ion channel activity;GO:0004890//GABA-A receptor activity;GO:0005254//chloride channel activity","GO:0042493//response to drug;GO:0034220//ion transmembrane transport;GO:0007214//gamma-aminobutyric acid signaling pathway","K05186//gamma-aminobutyric acid receptor subunit gamma","XP_008015527.1//PREDICTED: gamma-aminobutyric acid receptor subunit gamma-3 [Chlorocebus sabaeus]","1//3;4"]
[149420,4270,1.13,0.36,-1.65025396097288,{"v":9.57519657420609e-06,"d":"9.58E-06"},"Down",{"v":1.849822E-6,"d":"1.85E-06"},"PDIK1L","NA","GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding","NA","K17539//serine/threonine-protein kinase PDIK1L [EC:2.7.11.1]","EDL30020.1//PDLIM1 interacting kinase 1 like, isoform CRA_b, partial [Mus musculus];XP_004425820.2//PREDICTED: serine/threonine-protein kinase PDIK1L isoform X1 [Ceratotherium simum simum];XP_012295636.1//serine/threonine-protein kinase PDIK1L isoform X1 [Aotus nancymaae]","1//3;4"]
[23643,642,0.4,0.13,-1.62148837674627,0.529948014814815,"*",0.376212,"LY96","GO:0010008//endosome membrane;GO:0031226//intrinsic component of plasma membrane;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0046696//lipopolysaccharide receptor complex","GO:0015026//coreceptor activity;GO:0001875//lipopolysaccharide receptor activity","GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0097190//apoptotic signaling pathway;GO:0032496//response to lipopolysaccharide;GO:0007166//cell surface receptor signaling pathway;GO:0031666//positive regulation of lipopolysaccharide-mediated signaling pathway;GO:0032760//positive regulation of tumor necrosis factor production;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0045087//innate immune response;GO:0034142//toll-like receptor 4 signaling pathway;GO:0032497//detection of lipopolysaccharide;GO:0006968//cellular defense response;GO:0002224//toll-like receptor signaling pathway;GO:0006954//inflammatory response;GO:0034128//negative regulation of MyD88-independent toll-like receptor signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0070266//necroptotic process;GO:0002755//MyD88-dependent toll-like receptor signaling pathway","K05400//lymphocyte antigen 96","NP_001182726.1//lymphocyte antigen 96 isoform 2 precursor [Homo sapiens];NP_001123946.1//lymphocyte antigen 96 precursor [Pan troglodytes]","1//3;4"]
[80823,4000,0.73,0.24,-1.60486205815886,0.000827990507272727,"Down",2.28068E-4,"BHLHB9","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005829//cytosol","GO:0042803//protein homodimerization activity","GO:0050769//positive regulation of neurogenesis;GO:0043524//negative regulation of neuron apoptotic process;GO:0051965//positive regulation of synapse assembly;GO:0061003//positive regulation of dendritic spine morphogenesis;GO:0007611//learning or memory","NA","NP_085142.1//protein BHLHb9 [Homo sapiens]","1//3;2//1"]
[8863,6309,1.35,0.45,-1.58496250072116,{"v":8.47373717647059e-09,"d":"8.47E-09"},"Down",{"v":1.064124e-09,"d":"1.06E-09"},"PER3","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0031625//ubiquitin protein ligase binding;GO:0019900//kinase binding","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0032922//circadian regulation of gene expression;GO:0050821//protein stabilization;GO:0045187//regulation of circadian sleep/wake cycle, sleep","K21945//period circadian protein 3","NP_001276790.1//period circadian protein homolog 3 isoform 2 [Homo sapiens];NP_001276791.1//period circadian protein homolog 3 isoform 1 [Homo sapiens];NP_001276792.1//period circadian protein homolog 3 isoform 3 [Homo sapiens];XP_016858224.1//PREDICTED: period circadian protein homolog 3 isoform X15 [Homo sapiens];NP_058515.1//period circadian protein homolog 3 isoform 4 [Homo sapiens]","1//3;2//1"]
[257240,3039,0.03,0.01,-1.58496250072116,0.640145814894808,"*",0.500968,"KLHL34","GO:0005615//extracellular space;GO:0031463//Cul3-RING ubiquitin ligase complex","NA","GO:0016567//protein ubiquitination","K10469//kelch-like protein 34","NP_695002.1//kelch-like protein 34 [Homo sapiens]","2//1"]
[7730,2381,0.21,0.07,-1.58496250072116,0.306520596175908,"*",0.1806426,"ZNF177","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_004378617.1//PREDICTED: zinc finger protein 560 [Trichechus manatus latirostris];XP_017171168.1//PREDICTED: zinc finger protein 431-like isoform X1 [Mus musculus]","1//3;2//1"]
[29906,2627,0.03,0.01,-1.58496250072116,0.637646440796813,"*",0.500968,"ST8SIA5","GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0008373//sialyltransferase activity;GO:0003828//alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity","GO:0006486//protein glycosylation;GO:0006688//glycosphingolipid biosynthetic process;GO:0005975//carbohydrate metabolic process","K03369//alpha-N-acetyl-neuraminate alpha-2,8-sialyltransferase (sialyltransferase 8E) [EC:2.4.99.-]","NP_001294916.1//alpha-2,8-sialyltransferase 8E isoform 3 [Homo sapiens];NP_037437.2//alpha-2,8-sialyltransferase 8E isoform 2 [Homo sapiens];NP_001294915.1//alpha-2,8-sialyltransferase 8E isoform 1 [Homo sapiens]","1//3;5"]
[401498,5399,0.03,0.01,-1.58496250072116,0.733165520990549,"*",0.626454,"TMEM215","GO:0016021//integral component of membrane","NA","NA","NA","NP_997723.2//transmembrane protein 215 [Homo sapiens]","2//1"]
[6975,2810,0.03,0.01,-1.58496250072116,0.636125821303657,"*",0.500968,"TECTB","GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0031225//anchored component of membrane;GO:0005578//proteinaceous extracellular matrix","GO:0005201//extracellular matrix structural constituent","GO:0006501//C-terminal protein lipidation","K18274//uromodulin;K19899//pancreatic secretory granule membrane major glycoprotein GP2;K18273//alpha-tectorin","NP_478129.1//beta-tectorin precursor [Homo sapiens]","2//1"]
[55289,2373,0.03,0.01,-1.58496250072116,0.634562114978987,"*",0.500968,"ACOXL","NA","NA","NA","K00232//acyl-CoA oxidase [EC:1.3.3.6]","XP_018876900.1//PREDICTED: acyl-coenzyme A oxidase-like protein [Gorilla gorilla gorilla]","1//3"]
[64446,2292,0.03,0.01,-1.58496250072116,0.632655769784173,"*",0.500968,"DNAI2","GO:0036126//sperm flagellum;GO:0036157//outer dynein arm;GO:0005874//microtubule;GO:0009897//external side of plasma membrane;GO:0005737//cytoplasm;GO:0005930//axoneme;GO:0005858//axonemal dynein complex","GO:0003777//microtubule motor activity;GO:0045503//dynein light chain binding;GO:0045504//dynein heavy chain binding","GO:0003341//cilium movement;GO:0060271//cilium assembly;GO:0007368//determination of left/right symmetry;GO:0036158//outer dynein arm assembly","K11143//dynein intermediate chain 2, axonemal","NP_001166281.1//dynein intermediate chain 2, axonemal isoform 2 [Homo sapiens];NP_001340096.1//dynein intermediate chain 2, axonemal isoform 3 [Homo sapiens];EAW89148.1//dynein, axonemal, intermediate polypeptide 2, isoform CRA_e [Homo sapiens]","1//3;2//1;5"]
[151531,2410,0.03,0.01,-1.58496250072116,0.631557322389709,"*",0.500968,"UPP2","GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0045098//type III intermediate filament","GO:0004850//uridine phosphorylase activity","GO:0046135//pyrimidine nucleoside catabolic process;GO:0009116//nucleoside metabolic process;GO:0043097//pyrimidine nucleoside salvage;GO:0046108//uridine metabolic process;GO:0044206//UMP salvage;GO:0009166//nucleotide catabolic process","K00757//uridine phosphorylase [EC:2.4.2.3]","NP_001128570.1//uridine phosphorylase 2 isoform b [Homo sapiens]","1//3;3//A2MP1"]
[56100,4599,0.03,0.01,-1.58496250072116,0.391237386343655,"*",0.250726,"PCDHGB6","NA","NA","NA","K16496//protocadherin gamma subfamily B;K16495//protocadherin gamma subfamily A","XP_012501267.1//PREDICTED: protocadherin gamma-B6 isoform X9 [Propithecus coquereli];XP_015340968.1//PREDICTED: protocadherin gamma-B6 [Marmota marmota marmota]","1//3;2//1"]
[158248,2860,0.03,0.01,-1.58496250072116,0.628827819581958,"*",0.500968,"TTC16","NA","NA","NA","K22020//mucin-19","NP_659402.1//tetratricopeptide repeat protein 16 isoform 1 [Homo sapiens];NP_001303966.1//tetratricopeptide repeat protein 16 isoform 2 [Homo sapiens]","1//3;2//1"]
[1755,7656,0.03,0.01,-1.58496250072116,0.226906746117274,"*",0.1254848,"DMBT1","GO:0042589//zymogen granule membrane;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0019898//extrinsic component of membrane;GO:0005576//extracellular region;GO:0030670//phagocytic vesicle membrane;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0035375//zymogen binding;GO:1904399//heparan sulfate binding;GO:0001530//lipopolysaccharide binding;GO:0005044//scavenger receptor activity;GO:0038187//pattern recognition receptor activity;GO:0048306//calcium-dependent protein binding;GO:0070891//lipoteichoic acid binding;GO:0008329//signaling pattern recognition receptor activity","GO:0061844//antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0050829//defense response to Gram-negative bacterium;GO:0051607//defense response to virus;GO:0016032//viral process;GO:0044267//cellular protein metabolic process;GO:0006898//receptor-mediated endocytosis;GO:0007275//multicellular organism development;GO:0050830//defense response to Gram-positive bacterium;GO:0043152//induction of bacterial agglutination;GO:0045087//innate immune response;GO:0015031//protein transport;GO:0030855//epithelial cell differentiation","K13912//deleted in malignant brain tumors 1 protein","NP_060049.2//deleted in malignant brain tumors 1 protein isoform c precursor [Homo sapiens];NP_015568.2//deleted in malignant brain tumors 1 protein isoform b precursor [Homo sapiens];NP_004397.2//deleted in malignant brain tumors 1 protein isoform a precursor [Homo sapiens];NP_001307573.1//deleted in malignant brain tumors 1 protein isoform d precursor [Homo sapiens]","1//3;2//1"]
[54514,2379,0.03,0.01,-1.58496250072116,0.62602384667136,"*",0.500968,"DDX4","GO:0005730//nucleolus;GO:0071547//piP-body;GO:0071546//pi-body;GO:0043186//P granule;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm","GO:0004004//ATP-dependent RNA helicase activity;GO:0005524//ATP binding;GO:0004386//helicase activity;GO:0003676//nucleic acid binding;GO:0016887//ATPase activity","GO:0030317//flagellated sperm motility;GO:1990511//piRNA biosynthetic process;GO:0007141//male meiosis I;GO:0030154//cell differentiation;GO:0031047//gene silencing by RNA;GO:0007283//spermatogenesis;GO:0034587//piRNA metabolic process;GO:0007140//male meiotic nuclear division;GO:0010529//negative regulation of transposition;GO:0043046//DNA methylation involved in gamete generation;GO:0007275//multicellular organism development;GO:0010501//RNA secondary structure unwinding","K13982//probable ATP-dependent RNA helicase DDX4 [EC:3.6.4.13]","NP_001160006.1//probable ATP-dependent RNA helicase DDX4 isoform 4 [Homo sapiens];NP_077726.1//probable ATP-dependent RNA helicase DDX4 isoform 1 [Homo sapiens];NP_001136021.1//probable ATP-dependent RNA helicase DDX4 isoform 2 [Homo sapiens];NP_001160005.1//probable ATP-dependent RNA helicase DDX4 isoform 3 [Homo sapiens]","1//3;2//1"]
[110599588,671,2.35,0.8,-1.55458885167764,0.0365206129139686,"*",0.01482864,"ASDURF","NA","GO:0042803//protein homodimerization activity;GO:0004066//asparagine synthase (glutamine-hydrolyzing) activity","GO:0006541//glutamine metabolic process;GO:0006529//asparagine biosynthetic process","NA","XP_004484986.2//PREDICTED: asparagine synthetase domain-containing protein 1 [Dasypus novemcinctus]","1//3"]
[58480,4386,1.99,0.69,-1.52810016376548,{"v":1.43858359324324E-8,"d":"1.44E-08"},"Down",{"v":1.865998e-09,"d":"1.87E-09"},"RHOU","GO:0016020//membrane;GO:0042995//cell projection;GO:0005925//focal adhesion;GO:0002102//podosome;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005886//plasma membrane;GO:0000139//Golgi membrane","GO:0046872//metal ion binding;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0030036//actin cytoskeleton organization;GO:1903955//positive regulation of protein targeting to mitochondrion;GO:0008360//regulation of cell shape;GO:0016601//Rac protein signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0007010//cytoskeleton organization;GO:0000082//G1/S transition of mitotic cell cycle;GO:0051056//regulation of small GTPase mediated signal transduction","K07865//Ras homolog gene family, member U","BAD92748.1//ras homolog gene family, member U variant, partial [Homo sapiens]",5]
[284194,1243,0.2,0.07,-1.51457317282976,0.732736047155305,"*",0.626454,"LGALS9B","GO:0005829//cytosol","GO:0030246//carbohydrate binding","NA","K10093//galectin-9","NP_001036150.1//galectin-9B [Homo sapiens]","1//3"]
[25822,2465,4.12,1.46,-1.4966759683032,{"v":1.30483781462342e-09,"d":"1.30E-09"},"Down",{"v":1.485852E-10,"d":"1.49E-10"},"DNAJB5","GO:0005634//nucleus;GO:0005829//cytosol","GO:0051082//unfolded protein binding;GO:0051087//chaperone binding","GO:0006457//protein folding;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006986//response to unfolded protein","K09511//DnaJ homolog subfamily B member 5","XP_017721088.1//PREDICTED: dnaJ homolog subfamily B member 5 isoform X1 [Rhinopithecus bieti];NP_001128477.1//dnaJ homolog subfamily B member 5 isoform 1 [Homo sapiens];EFB22142.1//hypothetical protein PANDA_021017, partial [Ailuropoda melanoleuca];NP_001128476.2//dnaJ homolog subfamily B member 5 isoform 2 [Homo sapiens];NP_001336654.1//dnaJ homolog subfamily B member 5 isoform 4 [Homo sapiens]","1//3;2//1;5"]
[8911,9902,0.11,0.04,-1.4594316186373,0.0906561893336952,"*",0.0418208,"CACNA1I","GO:0005886//plasma membrane;GO:0005891//voltage-gated calcium channel complex","GO:0008332//low voltage-gated calcium channel activity;GO:0005245//voltage-gated calcium channel activity;GO:0005248//voltage-gated sodium channel activity","GO:0006810//transport;GO:0030317//flagellated sperm motility;GO:0007165//signal transduction;GO:0019228//neuronal action potential;GO:0086010//membrane depolarization during action potential;GO:0070509//calcium ion import;GO:0030431//sleep;GO:0045956//positive regulation of calcium ion-dependent exocytosis","K04856//voltage-dependent calcium channel T type alpha-1I","NP_001003406.1//voltage-dependent T-type calcium channel subunit alpha-1I isoform b [Homo sapiens];NP_066919.2//voltage-dependent T-type calcium channel subunit alpha-1I isoform a [Homo sapiens]","1//3;3//A2MP1"]
[56137,5404,0.63,0.23,-1.4537179674429,1.11777631212591E-3,"*",0.000315656,"PCDHA12","NA","NA","NA","K16493//protocadherin alpha","XP_003266535.1//PREDICTED: protocadherin alpha-12 isoform X2 [Nomascus leucogenys]","3//A2MP1;2//1"]
[4851,9322,4.03,1.48,-1.44518266289902,{"v":1.07732884411765E-31,"d":"1.08E-31"},"Down",{"v":2.75166e-33,"d":"2.75E-33"},"NOTCH1","GO:0009986//cell surface;GO:0016324//apical plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0001669//acrosomal vesicle;GO:0005912//adherens junction","GO:0005509//calcium ion binding;GO:0031490//chromatin DNA binding;GO:0019899//enzyme binding;GO:0001047//core promoter binding","GO:0031100//animal organ regeneration;GO:0003180//aortic valve morphogenesis;GO:1902263//apoptotic process involved in embryonic digit morphogenesis;GO:0060842//arterial endothelial cell differentiation;GO:0003162//atrioventricular node development","K02599//Notch 1","NP_060087.3//neurogenic locus notch homolog protein 1 preproprotein [Homo sapiens]",4]
[644943,2698,3.87,1.45,-1.41628066612948,{"v":4.87949823868313e-09,"d":"4.88E-09"},"Down",{"v":5.93824e-10,"d":"5.94E-10"},"RASSF10","NA","NA","NA","K09856//Ras association domain-containing protein 9/10","XP_003910253.2//ras association domain-containing protein 10 [Papio anubis]","2//1"]
[200373,2854,0.08,0.03,-1.41503749927884,0.531871005221701,"*",0.376212,"CFAP221","GO:0005929//cilium;GO:0005737//cytoplasm;GO:0005930//axoneme","GO:0005516//calmodulin binding","GO:0003341//cilium movement;GO:0060271//cilium assembly;GO:0044458//motile cilium assembly","K17570//hydrocephalus-inducing protein","NP_001257978.1//cilia- and flagella-associated protein 221 [Homo sapiens]","1//3"]
[253017,2843,0.08,0.03,-1.41503749927884,0.730329601226098,"*",0.626454,"TECRL","GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane","GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors;GO:0016491//oxidoreductase activity","GO:0042761//very long-chain fatty acid biosynthetic process","K10258//very-long-chain enoyl-CoA reductase [EC:1.3.1.93]","EAX05533.1//hCG2038358, partial [Homo sapiens]",4]
[100288413,2889,0.58,0.22,-1.39854937649027,0.027763867370109,"*",0.01083858,"ERVMER34-1","GO:0019031//viral envelope;GO:0016021//integral component of membrane","NA","NA","NA","NP_078810.1//endogenous retrovirus group MER34 member 1 Env polyprotein precursor [Homo sapiens]","1//3;5"]
[83538,3099,1.08,0.41,-1.39733549754539,0.00202086919174041,"*",0.000600416,"TTC25","GO:0005856//cytoskeleton;GO:0042995//cell projection;GO:0005737//cytoplasm","NA","NA","K15837//G-protein signaling modulator 2;K02145//V-type H+-transporting ATPase subunit A [EC:3.6.3.14];K09553//stress-induced-phosphoprotein 1","NP_001337248.1//tetratricopeptide repeat protein 25 isoform 2 [Homo sapiens];NP_113609.1//tetratricopeptide repeat protein 25 isoform 1 [Homo sapiens]","1//3;4"]
[5028,6802,0.13,0.05,-1.37851162325373,0.152252052368648,"*",0.0774604,"P2RY1","GO:0030425//dendrite;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0014069//postsynaptic density;GO:0044297//cell body;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0045211//postsynaptic membrane","GO:0045028//G-protein coupled purinergic nucleotide receptor activity;GO:0005524//ATP binding;GO:0004872//receptor activity;GO:0046982//protein heterodimerization activity;GO:0045032//ADP-activated adenosine receptor activity;GO:0031686//A1 adenosine receptor binding;GO:0097110//scaffold protein binding;GO:0043531//ADP binding;GO:0045031//ATP-activated adenosine receptor activity","GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0030168//platelet activation;GO:0007166//cell surface receptor signaling pathway;GO:0023019//signal transduction involved in regulation of gene expression;GO:0010700//negative regulation of norepinephrine secretion;GO:0071407//cellular response to organic cyclic compound;GO:0008347//glial cell migration;GO:0019233//sensory perception of pain;GO:0001934//positive regulation of protein phosphorylation;GO:0010469//regulation of receptor activity;GO:0060406//positive regulation of penile erection;GO:0090075//relaxation of muscle;GO:0097746//regulation of blood vessel diameter;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway;GO:0009612//response to mechanical stimulus;GO:0043270//positive regulation of ion transport;GO:0072659//protein localization to plasma membrane;GO:0042755//eating behavior;GO:0051100//negative regulation of binding;GO:0007568//aging;GO:0046887//positive regulation of hormone secretion;GO:0070848//response to growth factor;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0032962//positive regulation of inositol trisphosphate biosynthetic process;GO:0070374//positive regulation of ERK1 and ERK2 cascade","K04270//purinergic receptor P2Y, G protein-coupled, 1","NP_002554.1//P2Y purinoceptor 1 [Homo sapiens]",4]
[7026,4695,10.94,4.26,-1.36068740256672,{"v":3.148667088e-47,"d":"3.15E-47"},"Down",{"v":4.9278e-49,"d":"4.93E-49"},"NR2F2","GO:0005634//nucleus","GO:0003707//steroid hormone receptor activity;GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0042803//protein homodimerization activity;GO:0004879//nuclear receptor activity;GO:0043565//sequence-specific DNA binding;GO:0008270//zinc ion binding;GO:0001972//retinoic acid binding;GO:0003700//DNA binding transcription factor activity","GO:0009952//anterior/posterior pattern specification;GO:0045893//positive regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0032355//response to estradiol;GO:0060674//placenta blood vessel development;GO:0001893//maternal placenta development;GO:0001937//negative regulation of endothelial cell proliferation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0007165//signal transduction;GO:0009566//fertilization;GO:0001945//lymph vessel development;GO:0010596//negative regulation of endothelial cell migration;GO:0006351//transcription, DNA-templated;GO:0009956//radial pattern formation;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0060707//trophoblast giant cell differentiation;GO:0003084//positive regulation of systemic arterial blood pressure;GO:0060173//limb development;GO:0030900//forebrain development;GO:0001764//neuron migration;GO:0048514//blood vessel morphogenesis;GO:0007519//skeletal muscle tissue development;GO:0060849//regulation of transcription involved in lymphatic endothelial cell fate commitment;GO:0006629//lipid metabolic process","K08548//COUP transcription factor 2","XP_004468158.1//PREDICTED: LOW QUALITY PROTEIN: COUP transcription factor 2 [Dasypus novemcinctus];XP_004271711.1//PREDICTED: COUP transcription factor 2 isoform X3 [Orcinus orca];NP_899084.2//COUP transcription factor 2 isoform 2 [Mus musculus];XP_015273866.1//PREDICTED: COUP transcription factor 2 isoform X1 [Gekko japonicus]","1//3;3//A2MP1"]
[79819,1965,0.23,0.09,-1.3536369546147,0.631624178108758,"*",0.50972,"WDR78","GO:0005858//axonemal dynein complex","GO:0045503//dynein light chain binding;GO:0045504//dynein heavy chain binding","GO:0003341//cilium movement;GO:0002244//hematopoietic progenitor cell differentiation","K22001//insulin-like 5;K10409//dynein intermediate chain 1, axonemal","NP_079039.4//WD repeat-containing protein 78 isoform 1 [Homo sapiens];NP_996897.2//WD repeat-containing protein 78 isoform 2 [Homo sapiens]","4;2//1"]
[4297,16599,2.54,1.01,-1.33047320402037,{"v":2.1593444338983e-31,"d":"2.16E-31"},"Down",{"v":5.58288e-33,"d":"5.58E-33"},"KMT2A","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0071339//MLL1 complex;GO:0035097//histone methyltransferase complex;GO:0005829//cytosol","GO:0001046//core promoter sequence-specific DNA binding;GO:0042802//identical protein binding;GO:0042800//histone methyltransferase activity (H3-K4 specific);GO:0003680//AT DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0042803//protein homodimerization activity;GO:0070577//lysine-acetylated histone binding;GO:0045322//unmethylated CpG binding;GO:0003682//chromatin binding;GO:0008270//zinc ion binding;GO:0003700//DNA binding transcription factor activity;GO:0018024//histone-lysine N-methyltransferase activity","GO:2001040//positive regulation of cellular response to drug;GO:0032411//positive regulation of transporter activity;GO:0009791//post-embryonic development;GO:0048172//regulation of short-term neuronal synaptic plasticity;GO:0008285//negative regulation of cell proliferation;GO:0044648//histone H3-K4 dimethylation;GO:0006915//apoptotic process;GO:0035864//response to potassium ion;GO:0018026//peptidyl-lysine monomethylation;GO:0071440//regulation of histone H3-K14 acetylation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:1902036//regulation of hematopoietic stem cell differentiation;GO:0006461//protein complex assembly;GO:0009952//anterior/posterior pattern specification;GO:0008542//visual learning;GO:0051568//histone H3-K4 methylation;GO:0048873//homeostasis of number of cells within a tissue;GO:0045893//positive regulation of transcription, DNA-templated;GO:0035162//embryonic hemopoiesis;GO:0060216//definitive hemopoiesis;GO:1901674//regulation of histone H3-K27 acetylation;GO:0048536//spleen development;GO:0032922//circadian regulation of gene expression;GO:0051571//positive regulation of histone H3-K4 methylation;GO:0043984//histone H4-K16 acetylation;GO:0006351//transcription, DNA-templated;GO:0006306//DNA methylation;GO:0045652//regulation of megakaryocyte differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0035640//exploration behavior;GO:0051899//membrane depolarization;GO:0080182//histone H3-K4 trimethylation;GO:2000615//regulation of histone H3-K9 acetylation","K09186//histone-lysine N-methyltransferase MLL1 [EC:2.1.1.43]","NP_005924.2//histone-lysine N-methyltransferase 2A isoform 2 precursor [Homo sapiens];NP_001184033.1//histone-lysine N-methyltransferase 2A isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[1995,4661,0.05,0.02,-1.32192809488736,0.531165855400389,"*",0.376212,"ELAVL3","NA","GO:0003723//RNA binding;GO:0017091//AU-rich element binding","GO:0007399//nervous system development;GO:0030154//cell differentiation","K13208//ELAV like protein 2/3/4","XP_017450979.1//PREDICTED: ELAV-like protein 3 isoform X1 [Rattus norvegicus];XP_006242678.2//PREDICTED: ELAV-like protein 3 isoform X2 [Rattus norvegicus]","3//A2MP1;2//1"]
[219736,1037,0.75,0.3,-1.32192809488736,0.012955992,"*",0.00462714,"STOX1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005938//cell cortex;GO:0005829//cytosol;GO:0001650//fibrillar center;GO:0005813//centrosome;GO:0005737//cytoplasm","GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding","GO:0010468//regulation of gene expression;GO:0051897//positive regulation of protein kinase B signaling;GO:1904031//positive regulation of cyclin-dependent protein kinase activity;GO:0010629//negative regulation of gene expression;GO:0071500//cellular response to nitrosative stress;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0048839//inner ear development;GO:0010821//regulation of mitochondrion organization;GO:1904120//positive regulation of otic vesicle morphogenesis;GO:0006351//transcription, DNA-templated;GO:0010628//positive regulation of gene expression;GO:1901858//regulation of mitochondrial DNA metabolic process;GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:1902882//regulation of response to oxidative stress;GO:0051301//cell division;GO:0010971//positive regulation of G2/M transition of mitotic cell cycle;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0051881//regulation of mitochondrial membrane potential;GO:0007049//cell cycle;GO:0050679//positive regulation of epithelial cell proliferation;GO:0008284//positive regulation of cell proliferation","K04632//guanine nucleotide-binding protein G(s) subunit alpha;K09228//KRAB domain-containing zinc finger protein","NP_001123631.1//storkhead-box protein 1 isoform b [Homo sapiens];XP_019479904.1//PREDICTED: storkhead-box protein 1 isoform X3 [Hipposideros armiger];NP_689922.3//storkhead-box protein 1 isoform a [Homo sapiens]","4;2//1"]
[255394,2055,0.45,0.18,-1.32192809488736,0.184434724881066,"*",0.0970782,"TCP11L2","NA","NA","NA","K13999//cytoskeleton-associated protein 4","NP_001273191.1//T-complex protein 11-like protein 2 isoform 2 [Homo sapiens];NP_689985.1//T-complex protein 11-like protein 2 isoform 1 [Homo sapiens]","1//3;2//1"]
[8341,449,0.92,0.37,-1.31410859042806,0.357389370543899,"*",0.21966,"HIST1H2BN","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0000786//nucleosome","GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity","GO:0016567//protein ubiquitination;GO:0006334//nucleosome assembly","K11252//histone H2B","XP_003502246.1//PREDICTED: histone H2B type 1 isoform X1 [Cricetulus griseus]","3//A2MP1"]
[3172,4707,10.34,4.18,-1.30666133823405,{"v":5.07263337127937e-33,"d":"5.07E-33"},"Down",{"v":1.216238e-34,"d":"1.22E-34"},"HNF4A","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm","GO:0003707//steroid hormone receptor activity;GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0005102//receptor binding;GO:0044212//transcription regulatory region DNA binding;GO:0003705//transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding;GO:0042803//protein homodimerization activity;GO:0004879//nuclear receptor activity;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0008270//zinc ion binding;GO:0005504//fatty acid binding;GO:0003700//DNA binding transcription factor activity;GO:0001102//RNA polymerase II activating transcription factor binding","GO:0007596//blood coagulation;GO:0060398//regulation of growth hormone receptor signaling pathway;GO:0023019//signal transduction involved in regulation of gene expression;GO:0050796//regulation of insulin secretion;GO:0045893//positive regulation of transcription, DNA-templated;GO:0042593//glucose homeostasis;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0070328//triglyceride homeostasis;GO:0009749//response to glucose;GO:0019216//regulation of lipid metabolic process;GO:2000189//positive regulation of cholesterol homeostasis;GO:0006591//ornithine metabolic process;GO:0008285//negative regulation of cell proliferation;GO:0030308//negative regulation of cell growth;GO:0055091//phospholipid homeostasis;GO:0006805//xenobiotic metabolic process;GO:0010470//regulation of gastrulation;GO:0006351//transcription, DNA-templated;GO:0060395//SMAD protein signal transduction;GO:0007548//sex differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0055088//lipid homeostasis;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006629//lipid metabolic process","K07292//hepatocyte nuclear factor 4-alpha","NP_001025175.1//hepatocyte nuclear factor 4-alpha isoform 6 [Homo sapiens];NP_849181.1//hepatocyte nuclear factor 4-alpha isoform 3 [Homo sapiens];NP_001274113.1//hepatocyte nuclear factor 4-alpha isoform 10 [Homo sapiens];XP_008578997.1//PREDICTED: hepatocyte nuclear factor 4-alpha isoform X3 [Galeopterus variegatus];NP_000448.3//hepatocyte nuclear factor 4-alpha 2 [Homo sapiens];AAB48082.1//hepatocyte nuclear factor 4-alpha [Homo sapiens];NP_849180.1//hepatocyte nuclear factor 4-alpha isoform 1 [Homo sapiens];NP_001025174.1//hepatocyte nuclear factor 4-alpha isoform 4 [Homo sapiens];XP_008578995.1//PREDICTED: hepatocyte nuclear factor 4-alpha isoform X1 [Galeopterus variegatus];NP_787110.2//hepatocyte nuclear factor 4-alpha isoform 5 [Homo sapiens]","4;1//3;2//1"]
[6239,8076,3.96,1.61,-1.29843974196499,{"v":1.36005998947368e-23,"d":"1.36E-23"},"Down",{"v":5.17664E-25,"d":"5.18E-25"},"RREB1","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0016604//nuclear body;GO:0016607//nuclear speck;GO:0001650//fibrillar center;GO:0005737//cytoplasm","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0003676//nucleic acid binding;GO:0046872//metal ion binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0007165//signal transduction;GO:0006355//regulation of transcription, DNA-templated;GO:2000394//positive regulation of lamellipodium morphogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0033601//positive regulation of mammary gland epithelial cell proliferation;GO:0010634//positive regulation of epithelial cell migration;GO:0007275//multicellular organism development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:1903691//positive regulation of wound healing, spreading of epidermal cells;GO:0007265//Ras protein signal transduction","K20210//ras-responsive element-binding protein 1","NP_001003700.1//ras-responsive element-binding protein 1 isoform 3 [Homo sapiens];NP_001003698.1//ras-responsive element-binding protein 1 isoform 2 [Homo sapiens];NP_001003699.1//ras-responsive element-binding protein 1 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[126364,2430,1.39,0.57,-1.28605105855877,3.49955346896276E-3,"*",1.094076E-3,"LRRC25","GO:0016021//integral component of membrane","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K11447//histone demethylase [EC:1.14.11.-];K01064//wingless-type MMTV integration site family, member 9","NP_660299.2//leucine-rich repeat-containing protein 25 precursor [Homo sapiens]","2//1"]
[153478,12628,0.17,0.07,-1.28010791919274,0.0144204305894627,"*",0.00519168,"PLEKHG4B","NA","NA","NA","K08810//triple functional domain protein [EC:2.7.11.1];K18655//ATP-dependent RNA helicase DDX19/DBP5 [EC:3.6.4.13]","NP_443141.4//pleckstrin homology domain-containing family G member 4B [Homo sapiens]",4]
[55252,12894,4.01,1.66,-1.272418995108,{"v":1.0922956E-35,"d":"1.09E-35"},"Down",{"v":2.34542e-37,"d":"2.35E-37"},"ASXL2","NA","NA","NA","K11471//additional sex combs-like protein","XP_005576426.1//PREDICTED: putative Polycomb group protein ASXL2 isoform X3 [Macaca fascicularis]",5]
[84162,15592,0.84,0.35,-1.26303440583379,{"v":2.38198225373134e-09,"d":"2.38E-09"},"Down",{"v":2.79742e-10,"d":"2.80E-10"},"KIAA1109","GO:0016020//membrane;GO:0005634//nucleus;GO:0016021//integral component of membrane","NA","GO:0001558//regulation of cell growth;GO:0030856//regulation of epithelial cell differentiation","K05741//diaphanous 2","NP_056127.2//uncharacterized protein KIAA1109 [Homo sapiens]","3//A2MP1"]
[27244,3019,2.9,1.21,-1.26104585274034,{"v":1.31400523636364e-06,"d":"1.31E-06"},"Down",{"v":2.21688e-07,"d":"2.22E-07"},"SESN1","GO:0005634//nucleus;GO:0005829//cytosol;GO:0061700//GATOR2 complex;GO:0001650//fibrillar center;GO:0005737//cytoplasm","GO:0070728//leucine binding;GO:0051920//peroxiredoxin activity","GO:0034198//cellular response to amino acid starvation;GO:0098869//cellular oxidant detoxification;GO:1901031//regulation of response to reactive oxygen species;GO:0072593//reactive oxygen species metabolic process;GO:0042149//cellular response to glucose starvation;GO:1904262//negative regulation of TORC1 signaling","K10141//sestrin 1/3","NP_055269.1//sestrin-1 isoform 1 [Homo sapiens];NP_001186862.1//sestrin-1 isoform 2 [Homo sapiens]","1//3;2//1"]
[56125,3271,0.19,0.08,-1.24792751344359,0.367326217422025,"*",0.227814,"PCDHB11","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005509//calcium ion binding","GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules","K16494//protocadherin beta","XP_003846023.1//PREDICTED: LOW QUALITY PROTEIN: protocadherin beta-11 [Pan paniscus]","2//1"]
[9658,8626,1.42,0.6,-1.24285652389616,{"v":1.18634299542133E-8,"d":"1.19E-08"},"Down",{"v":1.524704e-09,"d":"1.52E-09"},"ZNF516","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0043565//sequence-specific DNA binding;GO:0000987//proximal promoter sequence-specific DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0033613//activating transcription factor binding;GO:0003676//nucleic acid binding","GO:0007165//signal transduction;GO:0009409//response to cold;GO:0007275//multicellular organism development;GO:0050873//brown fat cell differentiation;GO:0060612//adipose tissue development;GO:0006366//transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","NP_055458.1//zinc finger protein 516 [Homo sapiens]","3//A2MP1"]
[2257,5408,0.47,0.2,-1.23266075679027,0.0111969753,"*",0.00392532,"FGF12","GO:0005634//nucleus;GO:0005615//extracellular space;GO:0005622//intracellular","GO:0044325//ion channel binding;GO:0008083//growth factor activity;GO:0017080//sodium channel regulator activity;GO:0008201//heparin binding","GO:0007399//nervous system development;GO:0008344//adult locomotory behavior;GO:1905150//regulation of voltage-gated sodium channel activity;GO:2000649//regulation of sodium ion transmembrane transporter activity;GO:0003254//regulation of membrane depolarization;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0007165//signal transduction;GO:0007507//heart development;GO:0007267//cell-cell signaling;GO:0086002//cardiac muscle cell action potential involved in contraction;GO:0010765//positive regulation of sodium ion transport;GO:0098908//regulation of neuronal action potential;GO:0007254//JNK cascade;GO:2001258//negative regulation of cation channel activity;GO:1902305//regulation of sodium ion transmembrane transport;GO:0007268//chemical synaptic transmission;GO:0050905//neuromuscular process","K04358//fibroblast growth factor","NP_004104.3//fibroblast growth factor 12 isoform 2 [Homo sapiens];NP_066360.1//fibroblast growth factor 12 isoform 1 [Homo sapiens]","4;5"]
[3764,2406,0.07,0.03,-1.22239242133645,0.734079826584507,"*",0.626454,"KCNJ8","GO:0008282//inward rectifying potassium channel;GO:0030016//myofibril;GO:0005887//integral component of plasma membrane;GO:0042383//sarcolemma;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex","GO:0005524//ATP binding;GO:0017098//sulfonylurea receptor binding;GO:0005242//inward rectifier potassium channel activity;GO:1902282//voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization;GO:0015272//ATP-activated inward rectifier potassium channel activity","GO:0006813//potassium ion transport;GO:0009268//response to pH;GO:0001822//kidney development;GO:0007507//heart development;GO:0051607//defense response to virus;GO:0032496//response to lipopolysaccharide;GO:0043330//response to exogenous dsRNA;GO:0010107//potassium ion import;GO:0098915//membrane repolarization during ventricular cardiac muscle cell action potential;GO:1990573//potassium ion import across plasma membrane;GO:0042311//vasodilation","K05001//potassium inwardly-rectifying channel subfamily J member 8","NP_004973.1//ATP-sensitive inward rectifier potassium channel 8 [Homo sapiens]","3//A2MP1"]
[123591,2414,0.07,0.03,-1.22239242133645,0.730809625063901,"*",0.626454,"TMEM266","GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","NA","NA","K17382//serine beta-lactamase-like protein LACTB, mitochondrial;K13171//serine/arginine repetitive matrix protein 1","NP_689548.2//transmembrane protein 266 [Homo sapiens]","2//1"]
[26751,1806,1.9,0.82,-1.21230360371286,6.87215856900772E-3,"*",0.00228484,"SH3YL1","GO:0032587//ruffle membrane","GO:0019902//phosphatase binding;GO:0035091//phosphatidylinositol binding","GO:1900027//regulation of ruffle assembly;GO:0006661//phosphatidylinositol biosynthetic process","K20523//SH3 domain-containing YSC84-like protein 1","EAX01105.1//hCG1990170, isoform CRA_b, partial [Homo sapiens];XP_009440146.2//PREDICTED: SH3 domain-containing YSC84-like protein 1 isoform X1 [Pan troglodytes]","1//3;3//A2MP1;2//1"]
[6469,2210,0.67,0.29,-1.2081081953302,0.203233057687361,"*",0.1088176,"SHH","GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0009986//cell surface;GO:0005829//cytosol;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0043237//laminin-1 binding;GO:0005113//patched binding;GO:0008233//peptidase activity;GO:0005509//calcium ion binding;GO:0008270//zinc ion binding;GO:0005539//glycosaminoglycan binding;GO:0016015//morphogen activity","GO:0002320//lymphoid progenitor cell differentiation;GO:0043369//CD4-positive or CD8-positive, alpha-beta T cell lineage commitment;GO:0008209//androgen metabolic process;GO:0097190//apoptotic signaling pathway;GO:0051781//positive regulation of cell division;GO:0060840//artery development;GO:0045893//positive regulation of transcription, DNA-templated;GO:1900180//regulation of protein localization to nucleus;GO:0061189//positive regulation of sclerotome development;GO:0060738//epithelial-mesenchymal signaling involved in prostate gland development;GO:0072001//renal system development;GO:0048645//animal organ formation;GO:0016539//intein-mediated protein splicing;GO:0045880//positive regulation of smoothened signaling pathway;GO:0007224//smoothened signaling pathway;GO:0008284//positive regulation of cell proliferation","K11988//sonic hedgehog","NP_001297391.1//sonic hedgehog protein isoform 2 [Homo sapiens];EAX04543.1//sonic hedgehog homolog (Drosophila) [Homo sapiens]","1//3;3//A2MP1"]
[55552,2351,0.85,0.37,-1.19993757050875,0.0483660648648649,"*",0.0203892,"ZNF823","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_016790613.1//PREDICTED: zinc finger protein 823 isoform X3 [Pan troglodytes];XP_014197980.1//PREDICTED: zinc finger protein 823 isoform X1 [Pan paniscus]","1//3;3//A2MP1"]
[94241,5628,1.39,0.61,-1.18820373516062,{"v":1.8254248960396e-05,"d":"1.83E-05"},"Down",{"v":3.69336e-06,"d":"3.69E-06"},"TP53INP1","GO:0016605//PML body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0031410//cytoplasmic vesicle;GO:0005776//autophagosome","GO:0016209//antioxidant activity","GO:0071447//cellular response to hydroperoxide;GO:0006355//regulation of transcription, DNA-templated;GO:0010629//negative regulation of gene expression;GO:0007050//cell cycle arrest;GO:0045893//positive regulation of transcription, DNA-templated;GO:0034644//cellular response to UV;GO:0010506//regulation of autophagy;GO:0048102//autophagic cell death;GO:1904761//negative regulation of myofibroblast differentiation;GO:0008285//negative regulation of cell proliferation;GO:0071361//cellular response to ethanol;GO:0072703//cellular response to methyl methanesulfonate;GO:0006351//transcription, DNA-templated;GO:0030336//negative regulation of cell migration;GO:0010628//positive regulation of gene expression;GO:0009408//response to heat;GO:0048147//negative regulation of fibroblast proliferation;GO:0010508//positive regulation of autophagy;GO:0006915//apoptotic process;GO:1901796//regulation of signal transduction by p53 class mediator;GO:2001235//positive regulation of apoptotic signaling pathway;GO:0042981//regulation of apoptotic process;GO:0000045//autophagosome assembly","K15310//tumor protein p53-inducible nuclear protein 1","NP_001129205.1//tumor protein p53-inducible nuclear protein 1 isoform b [Homo sapiens];NP_150601.1//tumor protein p53-inducible nuclear protein 1 isoform a [Homo sapiens]","1//3;3//A2MP1"]
[54790,9753,0.66,0.29,-1.18641312423088,{"v":8.9891804162103e-05,"d":"8.99E-05"},"Down",{"v":2.05512e-05,"d":"2.06E-05"},"TET2","NA","GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0070579//methylcytosine dioxygenase activity;GO:0008198//ferrous iron binding","GO:0006211//5-methylcytosine catabolic process;GO:0014070//response to organic cyclic compound;GO:0006493//protein O-linked glycosylation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0030099//myeloid cell differentiation;GO:0080182//histone H3-K4 trimethylation;GO:0080111//DNA demethylation;GO:0007049//cell cycle","K11293//protein HIRA/HIR1;K14972//PAX-interacting protein 1;K13097//methylcytosine dioxygenase [EC:1.14.11.-]","NP_001120680.1//methylcytosine dioxygenase TET2 isoform a [Homo sapiens];NP_060098.3//methylcytosine dioxygenase TET2 isoform b [Homo sapiens]","4;2//1"]
[84456,4236,1.42,0.63,-1.17246719600477,0.000199252689425051,"Down",{"v":4.8597e-05,"d":"4.86E-05"},"L3MBTL3","GO:0005634//nucleus;GO:0005730//nucleolus","GO:0008270//zinc ion binding;GO:0003700//DNA binding transcription factor activity","GO:0043249//erythrocyte maturation;GO:0016569//covalent chromatin modification;GO:0030225//macrophage differentiation;GO:0006351//transcription, DNA-templated;GO:0030851//granulocyte differentiation","K11461//polycomb protein SCMH1","NP_115814.1//lethal(3)malignant brain tumor-like protein 3 isoform a [Homo sapiens];NP_001007103.1//lethal(3)malignant brain tumor-like protein 3 isoform b [Homo sapiens]","1//3;3//A2MP1"]
[84765,2943,0.27,0.12,-1.16992500144231,0.306120235199322,"*",0.1807516,"ZNF577","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","XP_014649658.1//PREDICTED: zinc finger protein 613-like [Ceratotherium simum simum];XP_014587901.1//PREDICTED: zinc finger protein 613 [Equus caballus]","1//3;2//1"]
[114792,3138,0.09,0.04,-1.16992500144231,0.529901286306322,"*",0.376212,"KLHL32","GO:0005737//cytoplasm;GO:0031463//Cul3-RING ubiquitin ligase complex","NA","GO:0009566//fertilization;GO:0016567//protein ubiquitination;GO:0007286//spermatid development;GO:0008584//male gonad development","K10468//kelch-like protein 32","XP_012299691.1//kelch-like protein 32 isoform X3 [Aotus nancymaae];NP_001310193.1//kelch-like protein 32 isoform o [Homo sapiens];NP_001310183.1//kelch-like protein 32 isoform g [Homo sapiens];XP_012299692.1//kelch-like protein 32 isoform X4 [Aotus nancymaae];NP_001310184.1//kelch-like protein 32 isoform h [Homo sapiens];XP_009449960.1//PREDICTED: kelch-like protein 32 isoform X1 [Pan troglodytes];NP_001310185.1//kelch-like protein 32 isoform i [Homo sapiens];XP_004580423.1//PREDICTED: kelch-like protein 32 isoform X1 [Ochotona princeps];NP_001310182.1//kelch-like protein 32 isoform f [Homo sapiens];NP_001273181.1//kelch-like protein 32 isoform d [Homo sapiens];XP_012299689.1//kelch-like protein 32 isoform X1 [Aotus nancymaae];NP_001273180.1//kelch-like protein 32 isoform c [Homo sapiens];XP_016865718.1//PREDICTED: kelch-like protein 32 isoform X3 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[55789,2516,8.73,3.9,-1.16250752987983,{"v":1.93748543929712e-13,"d":"1.94E-13"},"Down",{"v":1.51855e-14,"d":"1.52E-14"},"DEPDC1B","GO:0005829//cytosol;GO:0005622//intracellular","GO:0005096//GTPase activator activity","GO:0030177//positive regulation of Wnt signaling pathway;GO:0016477//cell migration;GO:0007165//signal transduction;GO:0035556//intracellular signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction","K20640//Rho GTPase-activating protein 19","XP_517749.3//PREDICTED: DEP domain-containing protein 1B isoform X1 [Pan troglodytes];XP_016808771.1//PREDICTED: DEP domain-containing protein 1B isoform X2 [Pan troglodytes]","1//3;2//1"]
[79827,2955,4.78,2.14,-1.1593998215796,{"v":5.44623474718526e-09,"d":"5.45E-09"},"Down",{"v":6.66204e-10,"d":"6.66E-10"},"CLMP","GO:0070062//extracellular exosome;GO:0009986//cell surface;GO:0005881//cytoplasmic microtubule;GO:0005923//bicellular tight junction;GO:0016021//integral component of membrane","NA","GO:0048565//digestive tract development","K06789//adipocyte-specific adhesion molecule","XP_012500334.1//PREDICTED: CXADR-like membrane protein [Propithecus coquereli]","3//A2MP1"]
[91461,2517,10.76,4.85,-1.14962142548213,{"v":4.2017235859375e-16,"d":"4.20E-16"},"Down",{"v":2.69348e-17,"d":"2.69E-17"},"PKDCC","GO:0005794//Golgi apparatus;GO:0005576//extracellular region","GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity","GO:0030282//bone mineralization;GO:0030154//cell differentiation;GO:0042997//negative regulation of Golgi to plasma membrane protein transport;GO:0035108//limb morphogenesis;GO:0032332//positive regulation of chondrocyte differentiation;GO:0035264//multicellular organism growth;GO:0030501//positive regulation of bone mineralization;GO:0048566//embryonic digestive tract development;GO:0048286//lung alveolus development;GO:0060021//palate development;GO:0001501//skeletal system development;GO:0015031//protein transport;GO:0018108//peptidyl-tyrosine phosphorylation","K17548//protein kinase domain-containing protein, cytoplasmic","NP_612379.2//extracellular tyrosine-protein kinase PKDCC precursor [Homo sapiens]","2//1"]
[2277,2084,0.42,0.19,-1.14438990933517,0.254688314370795,"*",0.1445636,"VEGFD","GO:0031093//platelet alpha granule lumen;GO:0016020//membrane;GO:0005615//extracellular space;GO:0005576//extracellular region","GO:0043185//vascular endothelial growth factor receptor 3 binding;GO:0005161//platelet-derived growth factor receptor binding;GO:0008083//growth factor activity;GO:0005172//vascular endothelial growth factor receptor binding;GO:0042803//protein homodimerization activity;GO:0042056//chemoattractant activity","GO:0050930//induction of positive chemotaxis;GO:0001525//angiogenesis;GO:0051781//positive regulation of cell division;GO:0071542//dopaminergic neuron differentiation;GO:0001666//response to hypoxia;GO:0002576//platelet degranulation;GO:0008283//cell proliferation;GO:0060754//positive regulation of mast cell chemotaxis;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0045766//positive regulation of angiogenesis;GO:0001938//positive regulation of endothelial cell proliferation;GO:0008284//positive regulation of cell proliferation","K05449//vascular endothelial growth factor C/D","NP_004460.1//vascular endothelial growth factor D preproprotein [Homo sapiens]",4]
[8794,1494,1.08,0.49,-1.14017765804826,0.0935732942799189,"*",0.0433188,"TNFRSF10C","GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0031225//anchored component of membrane","GO:0045569//TRAIL binding;GO:0004888//transmembrane signaling receptor activity;GO:0005031//tumor necrosis factor-activated receptor activity","GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007165//signal transduction;GO:0007275//multicellular organism development;GO:0097190//apoptotic signaling pathway;GO:0042127//regulation of cell proliferation;GO:0006955//immune response;GO:0032496//response to lipopolysaccharide;GO:0042981//regulation of apoptotic process;GO:0006954//inflammatory response","K04722//tumor necrosis factor receptor superfamily member 10","AAB71413.1//cytotoxic TRAIL receptor-3 [Homo sapiens]",4]
[10349,6348,0.11,0.05,-1.13750352374993,0.306217632665182,"*",0.1807516,"ABCA10","GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane","GO:0005524//ATP binding;GO:0042626//ATPase activity, coupled to transmembrane movement of substances","GO:0006869//lipid transport","K05652//ATP-binding cassette, subfamily A (ABC1), member 10","NP_525021.3//ATP-binding cassette sub-family A member 10 [Homo sapiens]","3//A2MP1"]
[133522,10602,1.01,0.46,-1.13464952669478,{"v":7.38291810558767e-07,"d":"7.38E-07"},"Down",{"v":1.199366E-7,"d":"1.20E-07"},"PPARGC1B","GO:0005634//nucleus;GO:0016592//mediator complex;GO:0005739//mitochondrion","GO:0030546//receptor activator activity;GO:0003723//RNA binding;GO:0030331//estrogen receptor binding;GO:0050682//AF-2 domain binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0003712//transcription cofactor activity;GO:0008134//transcription factor binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0034614//cellular response to reactive oxygen species;GO:0006355//regulation of transcription, DNA-templated;GO:0051591//response to cAMP;GO:0045672//positive regulation of osteoclast differentiation;GO:0001503//ossification;GO:0045780//positive regulation of bone resorption;GO:0006390//transcription from mitochondrial promoter;GO:0007015//actin filament organization;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0042327//positive regulation of phosphorylation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0060346//bone trabecula formation;GO:0010694//positive regulation of alkaline phosphatase activity;GO:0051384//response to glucocorticoid","K17962//peroxisome proliferator-activated receptor gamma coactivator 1-beta","NP_573570.3//peroxisome proliferator-activated receptor gamma coactivator 1-beta isoform 1 [Homo sapiens];NP_001166169.1//peroxisome proliferator-activated receptor gamma coactivator 1-beta isoform 2 [Homo sapiens];NP_001166170.1//peroxisome proliferator-activated receptor gamma coactivator 1-beta isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[54874,4382,5.61,2.57,-1.12623241141491,{"v":1.33505811471415e-15,"d":"1.34E-15"},"Down",{"v":8.91766e-17,"d":"8.92E-17"},"FNBP1L","GO:0070062//extracellular exosome;GO:0005856//cytoskeleton;GO:0005938//cell cortex;GO:0005829//cytosol;GO:0031410//cytoplasmic vesicle;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0008289//lipid binding;GO:0051020//GTPase binding;GO:0045296//cadherin binding","GO:0051491//positive regulation of filopodium assembly;GO:0072583//clathrin-dependent endocytosis;GO:0006900//vesicle budding from membrane;GO:0061024//membrane organization;GO:0010324//membrane invagination;GO:0016050//vesicle organization;GO:0060271//cilium assembly;GO:0006897//endocytosis;GO:0006914//autophagy;GO:0097320//plasma membrane tubulation;GO:0030050//vesicle transport along actin filament","K20121//formin-binding protein 1","NP_060207.2//formin-binding protein 1-like isoform 2 [Homo sapiens];NP_001020119.1//formin-binding protein 1-like isoform 1 [Homo sapiens];NP_001157945.1//formin-binding protein 1-like isoform 3 [Homo sapiens]","4;2//1"]
[57519,15584,0.78,0.36,-1.11547721741994,{"v":1.26833971877954E-7,"d":"1.27E-07"},"Down",{"v":1.847644e-08,"d":"1.85E-08"},"STARD9","GO:0005814//centriole;GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0005524//ATP binding;GO:0015485//cholesterol binding;GO:0003777//microtubule motor activity;GO:0008017//microtubule binding","GO:0007018//microtubule-based movement;GO:0008152//metabolic process;GO:0051225//spindle assembly","K16491//StAR-related lipid transfer protein 9","NP_065810.2//stAR-related lipid transfer protein 9 [Homo sapiens]","2//1"]
[8497,6461,0.26,0.12,-1.11547721741994,0.107309161927456,"*",0.0507458,"PPFIA4","GO:0048786//presynaptic active zone;GO:0009986//cell surface;GO:0005829//cytosol;GO:0005622//intracellular;GO:0045202//synapse","NA","GO:0007269//neurotransmitter secretion;GO:0014047//glutamate secretion","K07762//pappalysin-1 [EC:3.4.24.79];K06236//collagen, type I, alpha","NP_001291261.1//liprin-alpha-4 isoform 2 [Homo sapiens];NP_001291260.1//liprin-alpha-4 isoform 1 [Homo sapiens]","1//3"]
[54492,5833,2,0.93,-1.10469737866669,{"v":5.87715207227023e-07,"d":"5.88E-07"},"Down",{"v":9.36724e-08,"d":"9.37E-08"},"NEURL1B","GO:0005769//early endosome","GO:0046872//metal ion binding;GO:0016740//transferase activity;GO:0016874//ligase activity","GO:0016567//protein ubiquitination;GO:0007219//Notch signaling pathway;GO:0070086//ubiquitin-dependent endocytosis","K01931//protein neuralized [EC:2.3.2.27]","NP_001295107.1//E3 ubiquitin-protein ligase NEURL1B isoform hNEUR2-deltaNHR2 [Homo sapiens];NP_001136123.1//E3 ubiquitin-protein ligase NEURL1B isoform hNEUR2 [Homo sapiens];NP_001295106.1//E3 ubiquitin-protein ligase NEURL1B isoform hNEUR2-deltaNHR1 [Homo sapiens]","1//3;2//1"]
[23439,4773,0.94,0.44,-1.09515723304034,2.93996275203252E-3,"*",9.0551E-4,"ATP1B4","GO:0005890//sodium:potassium-exchanging ATPase complex;GO:0005637//nuclear inner membrane","NA","GO:0006813//potassium ion transport;GO:0006355//regulation of transcription, DNA-templated;GO:0006814//sodium ion transport","K01540//sodium/potassium-transporting ATPase subunit beta","XP_012594504.1//protein ATP1B4 isoform X1 [Microcebus murinus];XP_012594514.1//protein ATP1B4 isoform X2 [Microcebus murinus]","4;2//1"]
[4137,5660,0.79,0.37,-1.09432738254815,0.00159055350850743,"*",0.00046231,"MAPT","GO:0030424//axon;GO:1904115//axon cytoplasm;GO:0005874//microtubule;GO:0016607//nuclear speck;GO:0030673//axolemma;GO:0005737//cytoplasm;GO:0043005//neuron projection;GO:0044297//cell body;GO:0005875//microtubule associated complex;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0003779//actin binding;GO:0034452//dynactin binding;GO:0003677//DNA binding;GO:0034185//apolipoprotein binding;GO:0008017//microtubule binding","GO:0000226//microtubule cytoskeleton organization;GO:1990000//amyloid fibril formation;GO:0031175//neuron projection development;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0098930//axonal transport;GO:0048143//astrocyte activation","K04380//microtubule-associated protein tau","NP_001116539.1//microtubule-associated protein tau isoform 5 [Homo sapiens];NP_058518.1//microtubule-associated protein tau isoform 3 [Homo sapiens];NP_058519.3//microtubule-associated protein tau isoform 1 [Homo sapiens];NP_058525.1//microtubule-associated protein tau isoform 4 [Homo sapiens];NP_005901.2//microtubule-associated protein tau isoform 2 [Homo sapiens];NP_001190180.1//microtubule-associated protein tau isoform 7 [Homo sapiens];NP_001116538.2//microtubule-associated protein tau isoform 6 [Homo sapiens];NP_001190181.1//microtubule-associated protein tau isoform 8 [Homo sapiens]","1//3;4;3//A2MP1;5"]
[79925,3364,0.66,0.31,-1.09019780897158,0.0346578953908314,"*",0.01396166,"SPEF2","NA","NA","NA","K20045//intersectin;K18626//trichohyalin;K11515//inner centromere protein;K20478//golgin subfamily B member 1","NP_079143.3//sperm flagellar protein 2 isoform 1 [Homo sapiens];NP_653323.1//sperm flagellar protein 2 isoform 2 [Homo sapiens]","3//A2MP1"]
[5080,6732,1.1,0.52,-1.08091999538357,0.282329642736523,"*",0.1632754,"PAX6","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0000790//nuclear chromatin;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0070410//co-SMAD binding;GO:0003682//chromatin binding;GO:0043565//sequence-specific DNA binding;GO:0035035//histone acetyltransferase binding","GO:0048708//astrocyte differentiation;GO:0009887//animal organ morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0007275//multicellular organism development;GO:0006351//transcription, DNA-templated;GO:0001568//blood vessel development;GO:0007411//axon guidance","K08031//paired box protein 6","XP_014313762.1//PREDICTED: paired box protein Pax-6 isoform X1 [Myotis lucifugus];XP_013358393.1//PREDICTED: paired box protein Pax-6 isoform X3 [Chinchilla lanigera];XP_008001416.1//PREDICTED: paired box protein Pax-6 isoform X1 [Chlorocebus sabaeus];XP_013358392.1//PREDICTED: paired box protein Pax-6 isoform X1 [Chinchilla lanigera];XP_020934291.1//paired box protein Pax-6 isoform X1 [Sus scrofa]","4;1//3;5"]
[221191,1632,0.74,0.35,-1.08017034868398,0.179726705491087,"*",0.0940488,"PRSS54","GO:0005576//extracellular region","GO:0004252//serine-type endopeptidase activity","NA","K01317//acrosin [EC:3.4.21.10];K01324//plasma kallikrein [EC:3.4.21.34]","XP_016783984.1//PREDICTED: inactive serine protease 54 isoform X1 [Pan troglodytes];NP_001073961.1//inactive serine protease 54 isoform 1 precursor [Homo sapiens]","1//3"]
[10896,884,0.19,0.09,-1.07800251200127,0.730702898576123,"*",0.626454,"OCLM","GO:0016021//integral component of membrane","NA","GO:0007601//visual perception","NA","NP_071770.1//oculomedin [Homo sapiens]","3//A2MP1"]
[57600,6883,1.01,0.48,-1.07324898203064,0.000210418954743032,"Down",{"v":5.1518e-05,"d":"5.15E-05"},"FNIP2","NA","NA","NA","K20401//folliculin-interacting protein 2","XP_004040620.2//PREDICTED: folliculin-interacting protein 2 isoform X3 [Gorilla gorilla gorilla];XP_018881229.1//PREDICTED: folliculin-interacting protein 2 isoform X2 [Gorilla gorilla gorilla];XP_011530456.1//PREDICTED: folliculin-interacting protein 2 isoform X4 [Homo sapiens]","1//3;2//1"]
[22837,9406,0.61,0.29,-1.07275634243531,0.000890943717253839,"Down",2.4697E-4,"COBLL1","GO:0070062//extracellular exosome","GO:0003779//actin binding;GO:0003785//actin monomer binding;GO:0045296//cadherin binding","GO:0051639//actin filament network formation;GO:0030041//actin filament polymerization","K18623//protein cordon-bleu","NP_001265389.1//cordon-bleu protein-like 1 isoform 3 [Homo sapiens];Q53SF7.2//RecName: Full=Cordon-bleu protein-like 1;NP_001265387.1//cordon-bleu protein-like 1 isoform 1 [Homo sapiens]","4;1//3"]
[199786,2166,0.23,0.11,-1.06413033741972,0.499591840970839,"*",0.345342,"FAM129C","NA","NA","NA","K16145//mucin-16;K16628//collagen, type VII, alpha;K06236//collagen, type I, alpha","NP_775815.2//niban-like protein 2 isoform a [Homo sapiens];NP_001091994.1//niban-like protein 2 isoform b [Homo sapiens];NP_001308755.1//niban-like protein 2 isoform c [Homo sapiens]","1//3;4"]
[3199,1791,2.25,1.08,-1.05889368905357,0.00749054787607316,"*",0.00251248,"HOXA2","NA","NA","NA","K09302//homeobox protein HoxA/B2","XP_017501981.1//PREDICTED: homeobox protein Hox-A2 [Manis javanica]","3//A2MP1"]
[10484,4188,19.93,9.57,-1.05835088035303,{"v":1.59515095306859E-42,"d":"1.60E-42"},"Down",{"v":2.7661e-44,"d":"2.77E-44"},"SEC23A","GO:0070971//endoplasmic reticulum exit site;GO:0019898//extrinsic component of membrane;GO:0048471//perinuclear region of cytoplasm;GO:0000139//Golgi membrane;GO:0030127//COPII vesicle coat;GO:0005829//cytosol;GO:0005789//endoplasmic reticulum membrane;GO:0012507//ER to Golgi transport vesicle membrane","GO:0008270//zinc ion binding","GO:0006886//intracellular protein transport;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0048208//COPII vesicle coating;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0090110//cargo loading into COPII-coated vesicle;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I","K14006//protein transport protein SEC23","NP_006355.2//protein transport protein Sec23A [Homo sapiens]","3//A2MP1"]
[349149,1131,0.29,0.14,-1.05062607306997,0.61105690115252,"*",0.454716,"GJC3","GO:0005922//connexin complex;GO:0043209//myelin sheath;GO:0016021//integral component of membrane","GO:0042803//protein homodimerization activity","GO:0042552//myelination;GO:0007605//sensory perception of sound;GO:0007154//cell communication","K07628//gap junction gamma-3 protein","NP_853516.1//gap junction gamma-3 protein [Homo sapiens]","2//1"]
[346606,1207,0.31,0.15,-1.04730571477836,0.611211156512959,"*",0.454716,"MOGAT3","GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0003846//2-acylglycerol O-acyltransferase activity;GO:0004144//diacylglycerol O-acyltransferase activity;GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups","GO:0006071//glycerol metabolic process;GO:0019432//triglyceride biosynthetic process","K14456//2-acylglycerol O-acyltransferase 3 [EC:2.3.1.20 2.3.1.22]","NP_001274076.1//2-acylglycerol O-acyltransferase 3 isoform b [Homo sapiens];NP_835470.1//2-acylglycerol O-acyltransferase 3 isoform a [Homo sapiens]","1//3;3//A2MP1"]
[64168,5140,0.31,0.15,-1.04730571477836,0.142627760369123,"*",0.0715996,"NECAB1","NA","NA","NA","NA","XP_009453893.2//PREDICTED: N-terminal EF-hand calcium-binding protein 1 [Pan troglodytes]",4]
[901,5489,1.15,0.56,-1.03813512888677,0.000615240102897196,"Down",1.648446E-4,"CCNG2","GO:0005737//cytoplasm","NA","GO:0000075//cell cycle checkpoint;GO:0051301//cell division;GO:0051726//regulation of cell cycle;GO:0007049//cell cycle","K10146//cyclin G2","NP_004345.1//cyclin-G2 [Homo sapiens]","2//1"]
[3384,1153,0.43,0.21,-1.03394733192334,0.499365719923961,"*",0.345342,"ICAM2","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005887//integral component of plasma membrane;GO:0032154//cleavage furrow;GO:0001931//uropod;GO:0005886//plasma membrane","GO:0005178//integrin binding","GO:0007155//cell adhesion;GO:0030198//extracellular matrix organization;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0050776//regulation of immune response","K06523//intercellular adhesion molecule 2","XP_012357006.1//PREDICTED: intercellular adhesion molecule 2 isoform X1 [Nomascus leucogenys];BAD93115.1//intercellular adhesion molecule 2 precursor variant, partial [Homo sapiens]","1//3;3//A2MP1"]
[3156,4534,10.8,5.29,-1.02969168493681,{"v":1.91341294747826E-24,"d":"1.91E-24"},"Down",{"v":6.88752e-26,"d":"6.89E-26"},"HMGCR","GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005778//peroxisomal membrane","GO:0050661//NADP binding;GO:0004420//hydroxymethylglutaryl-CoA reductase (NADPH) activity;GO:0051721//protein phosphatase 2A binding;GO:0042803//protein homodimerization activity;GO:0070402//NADPH binding;GO:0042282//hydroxymethylglutaryl-CoA reductase activity;GO:0050662//coenzyme binding","GO:0008542//visual learning;GO:0043407//negative regulation of MAP kinase activity;GO:0015936//coenzyme A metabolic process;GO:0045471//response to ethanol;GO:0045540//regulation of cholesterol biosynthetic process;GO:0097756//negative regulation of blood vessel diameter;GO:0010664//negative regulation of striated muscle cell apoptotic process;GO:0045445//myoblast differentiation;GO:0007584//response to nutrient;GO:0019216//regulation of lipid metabolic process;GO:0010666//positive regulation of cardiac muscle cell apoptotic process;GO:0061045//negative regulation of wound healing;GO:0008299//isoprenoid biosynthetic process;GO:0061179//negative regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0006695//cholesterol biosynthetic process;GO:0032874//positive regulation of stress-activated MAPK cascade;GO:0051262//protein tetramerization;GO:0007568//aging;GO:0048643//positive regulation of skeletal muscle tissue development;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0006743//ubiquinone metabolic process","K00021//hydroxymethylglutaryl-CoA reductase (NADPH) [EC:1.1.1.34]","XP_011541659.1//PREDICTED: 3-hydroxy-3-methylglutaryl-Coenzyme A reductase isoform X1 [Homo sapiens];XP_011541661.1//PREDICTED: 3-hydroxy-3-methylglutaryl-Coenzyme A reductase isoform X3 [Homo sapiens]","1//3;2//1"]
[54454,8099,1.2,0.59,-1.02424754624668,{"v":1.64991017071651e-05,"d":"1.65E-05"},"Down",{"v":3.31552E-6,"d":"3.32E-06"},"ATAD2B","GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0042393//histone binding;GO:0005524//ATP binding;GO:0003682//chromatin binding;GO:0070577//lysine-acetylated histone binding;GO:0016887//ATPase activity","GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0031936//negative regulation of chromatin silencing","K14575//AAA family ATPase;K13525//transitional endoplasmic reticulum ATPase","NP_001341036.1//ATPase family AAA domain-containing protein 2B isoform 3 [Homo sapiens];NP_001229267.2//ATPase family AAA domain-containing protein 2B isoform 2 [Homo sapiens];NP_060022.2//ATPase family AAA domain-containing protein 2B isoform 1 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[389649,2077,1.56,0.77,-1.01861567816735,0.0172454121745035,"*",6.35988E-3,"C8orf86","NA","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K04487//cysteine desulfurase [EC:2.8.1.7];K01064//wingless-type MMTV integration site family, member 9","XP_001171412.2//PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein C8orf86 homolog [Pan troglodytes];NP_001290460.1//uncharacterized protein C8orf86 isoform 2 [Homo sapiens]","1//3;2//1"]
[23348,7493,3.2,1.58,-1.01814734671026,{"v":1.18912772339261E-11,"d":"1.19E-11"},"Down",{"v":1.088334E-12,"d":"1.09E-12"},"DOCK9","GO:0016020//membrane;GO:0012505//endomembrane system;GO:0005829//cytosol;GO:0005622//intracellular","GO:0005085//guanyl-nucleotide exchange factor activity;GO:0045296//cadherin binding","GO:0007596//blood coagulation;GO:0007264//small GTPase mediated signal transduction;GO:0043547//positive regulation of GTPase activity","K21853//dedicator of cytokinesis protein 9/10/11","EAX08996.1//dedicator of cytokinesis 9, isoform CRA_c [Homo sapiens];NP_001123521.1//dedicator of cytokinesis protein 9 isoform c [Homo sapiens];NP_001123522.1//dedicator of cytokinesis protein 9 isoform d [Homo sapiens];NP_001123520.1//dedicator of cytokinesis protein 9 isoform b [Homo sapiens];EAX09003.1//dedicator of cytokinesis 9, isoform CRA_j [Homo sapiens]","1//3;2//1"]
[1184,9839,1.25,0.62,-1.01158797427521,{"v":2.45735163623446e-06,"d":"2.46E-06"},"Down",{"v":4.33044e-07,"d":"4.33E-07"},"CLCN5","GO:0005765//lysosomal membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0045177//apical part of cell;GO:0005886//plasma membrane","GO:0042802//identical protein binding;GO:0005247//voltage-gated chloride channel activity","NA","K05012//chloride channel 3/4/5","NP_001259031.1//H(+)/Cl(-) exchange transporter 5 isoform c [Homo sapiens];XP_012666732.1//PREDICTED: H(+)/Cl(-) exchange transporter 5 isoform X1 [Otolemur garnettii]","4;1//3;3//A2MP1"]
[4293,11120,3.18,1.58,-1.00910220710725,{"v":1.90237868320856e-17,"d":"1.90E-17"},"Down",{"v":1.113512E-18,"d":"1.11E-18"},"MAP3K9","GO:0016021//integral component of membrane;GO:0005737//cytoplasm","GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0004706//JUN kinase kinase kinase activity;GO:0042803//protein homodimerization activity;GO:0004713//protein tyrosine kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004708//MAP kinase kinase activity;GO:0004672//protein kinase activity","GO:0043065//positive regulation of apoptotic process;GO:0006355//regulation of transcription, DNA-templated;GO:0006468//protein phosphorylation;GO:0006351//transcription, DNA-templated;GO:0046777//protein autophosphorylation;GO:0006915//apoptotic process;GO:0007257//activation of JUN kinase activity","K04417//mitogen-activated protein kinase kinase kinase 9 [EC:2.7.11.25]","NP_001271159.1//mitogen-activated protein kinase kinase kinase 9 isoform 2 [Homo sapiens];NP_149132.2//mitogen-activated protein kinase kinase kinase 9 isoform 1 [Homo sapiens];NP_001271160.1//mitogen-activated protein kinase kinase kinase 9 isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[57763,2198,4.01,2,-1.0036022366802,{"v":7.72465334919756e-05,"d":"7.72E-05"},"Down",{"v":1.747646e-05,"d":"1.75E-05"},"ANKRA2","GO:0016020//membrane;GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0043234//protein complex;GO:0005829//cytosol;GO:1990393//3M complex;GO:0005737//cytoplasm","GO:0042826//histone deacetylase binding;GO:0031625//ubiquitin protein ligase binding;GO:0003712//transcription cofactor activity;GO:0050750//low-density lipoprotein particle receptor binding;GO:0019901//protein kinase binding","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0043254//regulation of protein complex assembly","K21486//ankyrin repeat family A protein 2","XP_008539463.1//PREDICTED: ankyrin repeat family A protein 2 isoform X1 [Equus przewalskii]",4]
[56903,4271,0.02,0.01,-1,0.641171607403253,"*",0.500968,"PAPOLB","GO:0005634//nucleus","GO:0003723//RNA binding;GO:0004652//polynucleotide adenylyltransferase activity","GO:0031123//RNA 3'-end processing;GO:0043631//RNA polyadenylation","K14376//poly(A) polymerase [EC:2.7.7.19]","XP_003934837.1//PREDICTED: poly(A) polymerase beta [Saimiri boliviensis boliviensis]",4]
[2706,2347,0.14,0.07,-1,0.611159729406815,"*",0.454716,"GJB2","GO:0005922//connexin complex;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0048471//perinuclear region of cytoplasm;GO:0044297//cell body;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0016328//lateral plasma membrane;GO:0097449//astrocyte projection;GO:0005886//plasma membrane","GO:0005243//gap junction channel activity;GO:0042802//identical protein binding","GO:0032496//response to lipopolysaccharide;GO:0032570//response to progesterone;GO:0046677//response to antibiotic;GO:1905867//epididymis development;GO:0016264//gap junction assembly;GO:0032355//response to estradiol;GO:0048839//inner ear development;GO:0044752//response to human chorionic gonadotropin;GO:0006810//transport;GO:0002931//response to ischemia;GO:0071377//cellular response to glucagon stimulus;GO:0046697//decidualization;GO:0007267//cell-cell signaling;GO:0032526//response to retinoic acid;GO:0007568//aging;GO:0071549//cellular response to dexamethasone stimulus;GO:0034599//cellular response to oxidative stress;GO:0007605//sensory perception of sound","K07621//gap junction beta-2 protein","NP_003995.2//gap junction beta-2 protein [Homo sapiens]",5]
[2615,4222,0.04,0.02,-1,0.73413368028758,"*",0.626454,"LRRC32","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane","NA","GO:0046007//negative regulation of activated T cell proliferation;GO:0010628//positive regulation of gene expression;GO:0050710//negative regulation of cytokine secretion","K17256//insulin-like growth factor-binding protein complex acid labile subunit;K07620//gap junction beta-1 protein","NP_005503.1//leucine-rich repeat-containing protein 32 precursor [Homo sapiens]","1//3;2//1"]
[389857,1620,0.02,0.01,-1,1.00078622651449,"*",0.999032,"CENPVL1","NA","NA","NA","K22020//mucin-19;K16630//collagen, type XXII, alpha","EAW62899.1//hCG1793638, partial [Homo sapiens]","1//3"]
[729159,2115,1.18,0.59,-1,0.0453602738346315,"*",0.01895738,"LOC729159","NA","NA","NA","K06236//collagen, type I, alpha","NP_001269230.1//putative UPF0607 protein ENSP00000381418 [Homo sapiens]","2//1"]
[8706,3342,0.02,0.01,-1,1.00072346949269,"*",0.999032,"B3GALNT1","NA","NA","NA","K00719//galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase [EC:2.4.1.79]","NP_001336091.1//UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1 isoform a [Homo sapiens]","1//3;3//A2MP1;2//1"]
[168620,706,0.24,0.12,-1,0.733595498570486,"*",0.626454,"BHLHA15","GO:0005634//nucleus","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0042803//protein homodimerization activity;GO:0046983//protein dimerization activity","GO:0006851//mitochondrial calcium ion transmembrane transport;GO:0007186//G-protein coupled receptor signaling pathway;GO:0010832//negative regulation of myotube differentiation;GO:0007267//cell-cell signaling;GO:0019722//calcium-mediated signaling;GO:0007030//Golgi organization;GO:0042149//cellular response to glucose starvation;GO:0042593//glucose homeostasis;GO:0048469//cell maturation;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0048312//intracellular distribution of mitochondria","K08040//class B basic helix-loop-helix protein 8","NP_803238.1//class A basic helix-loop-helix protein 15 [Homo sapiens]","3//A2MP1"]
[441495,1620,0.02,0.01,-1,1.00015901027827,"*",0.999032,"CENPVL2","NA","NA","NA","K22020//mucin-19;K16630//collagen, type XXII, alpha","EAW62899.1//hCG1793638, partial [Homo sapiens]","1//3"]
[388553,2754,0.06,0.03,-1,0.732789703866432,"*",0.626454,"BHMG1","GO:0005634//nucleus","GO:0003677//DNA binding;GO:0046983//protein dimerization activity","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K08871//bromodomain-containing protein 2;K14562//Treacher Collins syndrome protein","XP_011525873.1//PREDICTED: basic helix-loop-helix and HMG box domain-containing protein 1 isoform X1 [Homo sapiens]","1//3"]
[9358,3317,0.08,0.04,-1,0.531353712466843,"*",0.376212,"ITGBL1","GO:0005615//extracellular space","NA","GO:0007155//cell adhesion;GO:0007229//integrin-mediated signaling pathway","K06589//integrin beta 6;K06493//integrin beta 3;K06252//tenascin","NP_001258685.1//integrin beta-like protein 1 isoform 3 [Homo sapiens];NP_004782.1//integrin beta-like protein 1 isoform 1 precursor [Homo sapiens];NP_001258684.1//integrin beta-like protein 1 isoform 2 precursor [Homo sapiens];XP_001150034.1//PREDICTED: integrin beta-like protein 1 isoform X1 [Pan troglodytes]","1//3;2//1"]
[83715,3531,0.04,0.02,-1,0.732575124158126,"*",0.626454,"ESPN","GO:0005903//brush border;GO:0032426//stereocilium tip;GO:0005902//microvillus;GO:0005737//cytoplasm;GO:0031941//filamentous actin","GO:0051015//actin filament binding;GO:0017124//SH3 domain binding","GO:0007626//locomotory behavior;GO:0051491//positive regulation of filopodium assembly;GO:0007605//sensory perception of sound;GO:0051017//actin filament bundle assembly;GO:0030046//parallel actin filament bundle assembly;GO:0051494//negative regulation of cytoskeleton organization","K18441//cytohesin","NP_113663.2//espin [Homo sapiens]","2//1"]
[10343,7660,0.02,0.01,-1,0.39188817260274,"*",0.250726,"PKDREJ","GO:0016020//membrane;GO:0016021//integral component of membrane","GO:0005509//calcium ion binding;GO:0005262//calcium channel activity","GO:0007340//acrosome reaction;GO:0050982//detection of mechanical stimulus","K19921//polycystic kidney disease and receptor for egg jelly-related protein","NP_006062.1//polycystic kidney disease and receptor for egg jelly-related protein precursor [Homo sapiens]","1//3"]
[3071,3780,0.02,0.01,-1,0.633256534937089,"*",0.500968,"NCKAP1L","GO:0031209//SCAR complex;GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005829//cytosol","GO:0030295//protein kinase activator activity;GO:0032403//protein complex binding;GO:0005096//GTPase activator activity","GO:0060100//positive regulation of phagocytosis, engulfment;GO:0042102//positive regulation of T cell proliferation;GO:0032715//negative regulation of interleukin-6 production;GO:0030866//cortical actin cytoskeleton organization;GO:0030890//positive regulation of B cell proliferation;GO:0048821//erythrocyte development;GO:0030838//positive regulation of actin filament polymerization;GO:0043372//positive regulation of CD4-positive, alpha-beta T cell differentiation;GO:0035509//negative regulation of myosin-light-chain-phosphatase activity;GO:0050853//B cell receptor signaling pathway;GO:0042493//response to drug;GO:0090023//positive regulation of neutrophil chemotaxis;GO:0030593//neutrophil chemotaxis;GO:0070358//actin polymerization-dependent cell motility;GO:0043066//negative regulation of apoptotic process;GO:0045579//positive regulation of B cell differentiation;GO:0043029//T cell homeostasis;GO:0032700//negative regulation of interleukin-17 production;GO:0045588//positive regulation of gamma-delta T cell differentiation;GO:0045648//positive regulation of erythrocyte differentiation;GO:0043378//positive regulation of CD8-positive, alpha-beta T cell differentiation;GO:0001782//B cell homeostasis;GO:0006461//protein complex assembly;GO:0033630//positive regulation of cell adhesion mediated by integrin;GO:0030011//maintenance of cell polarity","K05750//NCK-associated protein 1","XP_010372155.1//PREDICTED: nck-associated protein 1-like [Rhinopithecus roxellana]","1//3;4"]
[401145,3927,0.02,0.01,-1,0.99984569688616,"*",0.999032,"CCSER1","NA","NA","NA","NA","NP_997374.1//serine-rich coiled-coil domain-containing protein 1 isoform 2 [Homo sapiens];NP_001138537.1//serine-rich coiled-coil domain-containing protein 1 isoform 1 [Homo sapiens]","1//3;2//1"]
[2525,2342,0.06,0.03,-1,0.731985677419355,"*",0.626454,"FUT3","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0032580//Golgi cisterna membrane;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0046920//alpha-(1->3)-fucosyltransferase activity;GO:0008417//fucosyltransferase activity;GO:0017060//3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity","GO:0006486//protein glycosylation;GO:0043413//macromolecule glycosylation;GO:0009988//cell-cell recognition;GO:0009312//oligosaccharide biosynthetic process;GO:0006672//ceramide metabolic process","K00716//galactoside 3(4)-fucosyltransferase 3 [EC:2.4.1.65]","NP_000140.1//galactoside 3(4)-L-fucosyltransferase [Homo sapiens]","1//3;3//A2MP1"]
[286530,4240,0.02,0.01,-1,0.631358014358974,"*",0.500968,"P2RY8","GO:0005887//integral component of plasma membrane","GO:0045028//G-protein coupled purinergic nucleotide receptor activity;GO:0004930//G-protein coupled receptor activity","GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway;GO:0035025//positive regulation of Rho protein signal transduction","K08386//purinergic receptor P2Y, G protein-coupled, 8","XP_006724506.2//PREDICTED: P2Y purinoceptor 8 isoform X1 [Homo sapiens]",4]
[1620,3196,0.02,0.01,-1,0.631208615870011,"*",0.500968,"BRINP1","GO:0030425//dendrite;GO:0005783//endoplasmic reticulum;GO:0005737//cytoplasm;GO:0043025//neuronal cell body","NA","GO:0050768//negative regulation of neurogenesis;GO:0035176//social behavior;GO:0045666//positive regulation of neuron differentiation;GO:0045930//negative regulation of mitotic cell cycle;GO:0045786//negative regulation of cell cycle;GO:0008219//cell death;GO:0007050//cell cycle arrest;GO:0001662//behavioral fear response;GO:0071300//cellular response to retinoic acid;GO:0035640//exploration behavior;GO:0071625//vocalization behavior;GO:0007614//short-term memory;GO:0042711//maternal behavior","K15164//mediator of RNA polymerase II transcription subunit 13;K21125//mucin-5AC","NP_055433.2//BMP/retinoic acid-inducible neural-specific protein 1 precursor [Homo sapiens]","2//1"]
[100652824,4147,0.02,0.01,-1,0.63076084432884,"*",0.500968,"KIAA2012","NA","NA","NA","K12484//Rab11 family-interacting protein 1/2/5;K18626//trichohyalin","XP_006712235.1//PREDICTED: uncharacterized protein KIAA2012 isoform X3 [Homo sapiens]","2//1"]
[55567,12528,0.02,0.01,-1,0.530415753574581,"*",0.376212,"DNAH3","NA","NA","NA","K10408//dynein heavy chain, axonemal","XP_018868309.1//PREDICTED: dynein heavy chain 3, axonemal [Gorilla gorilla gorilla]","1//3;2//1"]
[8483,4484,0.04,0.02,-1,0.731129991670929,"*",0.626454,"CILP","GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005578//proteinaceous extracellular matrix","NA","GO:0043569//negative regulation of insulin-like growth factor receptor signaling pathway","K19031//cell migration-inducing and hyaluronan-binding protein [EC:3.2.1.35]","NP_003604.3//cartilage intermediate layer protein 1 preproprotein [Homo sapiens]","3//A2MP1"]
[57619,11023,0.96,0.48,-1,{"v":1.07702490629012E-5,"d":"1.08E-05"},"Down",{"v":2.10092e-06,"d":"2.10E-06"},"SHROOM3","GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0016324//apical plasma membrane;GO:0043296//apical junction complex;GO:0005737//cytoplasm;GO:0005912//adherens junction","GO:0051015//actin filament binding","GO:0007389//pattern specification process;GO:0000902//cell morphogenesis;GO:0002064//epithelial cell development;GO:0001843//neural tube closure;GO:0008360//regulation of cell shape;GO:0043482//cellular pigment accumulation;GO:0045176//apical protein localization","K18625//protein Shroom","NP_065910.3//protein Shroom3 [Homo sapiens]","3//A2MP1"]
[54887,9658,2.48,1.24,-1,{"v":9.14757807345807e-12,"d":"9.15E-12"},"Down",{"v":8.2634e-13,"d":"8.26E-13"},"UHRF1BP1","NA","GO:0042802//identical protein binding;GO:0042826//histone deacetylase binding","NA","K06245//laminin, beta 4;K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K04613//vomeronasal 2 receptor;K12025//tripartite motif-containing protein 52","NP_060224.3//UHRF1-binding protein 1 [Homo sapiens]","3//A2MP1"]
[84688,1095,0.6,0.3,-1,1.01671034732678,"*",0.997616,"C9orf24","GO:0005634//nucleus;GO:0002177//manchette;GO:0048471//perinuclear region of cytoplasm","GO:0043014//alpha-tubulin binding","GO:0030154//cell differentiation;GO:0007283//spermatogenesis;GO:0043623//cellular protein complex assembly","K18634//spermatid-specific manchette-related protein 1","XP_003829848.1//PREDICTED: spermatid-specific manchette-related protein 1 isoform X3 [Pan paniscus];NP_115985.2//spermatid-specific manchette-related protein 1 isoform 1 [Homo sapiens];XP_008953425.1//PREDICTED: spermatid-specific manchette-related protein 1 isoform X2 [Pan paniscus];EAW58459.1//chromosome 9 open reading frame 24, isoform CRA_d [Homo sapiens]","1//3;3//A2MP1;2//1"]
[55613,2675,0.18,0.09,-1,0.498688583258,"*",0.345342,"MTMR8","GO:0005635//nuclear envelope;GO:0005829//cytosol","GO:0004725//protein tyrosine phosphatase activity;GO:0004438//phosphatidylinositol-3-phosphatase activity;GO:0052629//phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity","GO:0010506//regulation of autophagy;GO:0006661//phosphatidylinositol biosynthetic process;GO:0046856//phosphatidylinositol dephosphorylation","K18083//myotubularin-related protein 6/7/8 [EC:3.1.3.64 3.1.3.95]","NP_060147.2//myotubularin-related protein 8 [Homo sapiens]","3//A2MP1"]
[440854,3841,0.02,0.01,-1,0.626170800625978,"*",0.500968,"CAPN14","GO:0005622//intracellular;GO:0005737//cytoplasm","GO:0004198//calcium-dependent cysteine-type endopeptidase activity;GO:0005509//calcium ion binding","GO:0006508//proteolysis","K13442//calpain-14 [EC:3.4.22.-]","NP_001308199.1//calpain-14 isoform 2 [Homo sapiens];NP_001138594.1//calpain-14 isoform 1 [Homo sapiens]","1//3"]
[324,10448,2.32,1.16,-1,{"v":3.47541069727403E-12,"d":"3.48E-12"},"Down",{"v":3.03288e-13,"d":"3.03E-13"},"APC","GO:0005874//microtubule;GO:0030877//beta-catenin destruction complex;GO:0032587//ruffle membrane;GO:0005737//cytoplasm;GO:0005913//cell-cell adherens junction;GO:0005829//cytosol;GO:0005923//bicellular tight junction;GO:0016328//lateral plasma membrane;GO:0005886//plasma membrane;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005813//centrosome;GO:0005912//adherens junction;GO:0030027//lamellipodium;GO:0048471//perinuclear region of cytoplasm;GO:0016342//catenin complex;GO:1990909//Wnt signalosome;GO:0000776//kinetochore","GO:0045295//gamma-catenin binding;GO:0070840//dynein complex binding;GO:0042802//identical protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0008017//microtubule binding;GO:0019901//protein kinase binding;GO:0019887//protein kinase regulator activity;GO:0051010//microtubule plus-end binding;GO:0008013//beta-catenin binding","GO:1904781//positive regulation of protein localization to centrosome;GO:0016477//cell migration;GO:0030335//positive regulation of cell migration;GO:0008286//insulin receptor signaling pathway;GO:0030178//negative regulation of Wnt signaling pathway;GO:1904886//beta-catenin destruction complex disassembly;GO:0051260//protein homooligomerization;GO:0007094//mitotic spindle assembly checkpoint;GO:0007050//cell cycle arrest;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0000281//mitotic cytokinesis;GO:0051988//regulation of attachment of spindle microtubules to kinetochore;GO:0016579//protein deubiquitination;GO:0007026//negative regulation of microtubule depolymerization;GO:0006974//cellular response to DNA damage stimulus;GO:0010942//positive regulation of cell death;GO:0008285//negative regulation of cell proliferation;GO:0032886//regulation of microtubule-based process;GO:0031274//positive regulation of pseudopodium assembly;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0007155//cell adhesion;GO:0060070//canonical Wnt signaling pathway;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0070830//bicellular tight junction assembly;GO:0097194//execution phase of apoptosis;GO:0045732//positive regulation of protein catabolic process;GO:0016055//Wnt signaling pathway;GO:0006461//protein complex assembly;GO:1904885//beta-catenin destruction complex assembly","K02085//adenomatosis polyposis coli protein","NP_001341826.1//adenomatous polyposis coli protein isoform d [Homo sapiens];NP_001341831.1//adenomatous polyposis coli protein isoform i [Homo sapiens];XP_016809115.1//PREDICTED: adenomatous polyposis coli protein isoform X4 [Pan troglodytes];NP_001120983.2//adenomatous polyposis coli protein isoform a [Homo sapiens];NP_001341828.1//adenomatous polyposis coli protein isoform f [Homo sapiens];XP_016809114.1//PREDICTED: adenomatous polyposis coli protein isoform X2 [Pan troglodytes];NP_001341832.1//adenomatous polyposis coli protein isoform j [Homo sapiens];NP_001341825.1//adenomatous polyposis coli protein isoform c [Homo sapiens];NP_000029.2//adenomatous polyposis coli protein isoform b [Homo sapiens];XP_016809117.1//PREDICTED: adenomatous polyposis coli protein isoform X7 [Pan troglodytes]","1//3;2//1;5"]
[5602,6718,0.2,0.1,-1,0.203161797849462,"*",0.1088176,"MAPK10","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0043005//neuron projection","GO:0004705//JUN kinase activity;GO:0005524//ATP binding;GO:0004708//MAP kinase kinase activity;GO:0004707//MAP kinase activity","GO:0010468//regulation of gene expression;GO:0007165//signal transduction;GO:0009416//response to light stimulus;GO:0006468//protein phosphorylation;GO:0048511//rhythmic process;GO:0051090//regulation of DNA binding transcription factor activity;GO:0048666//neuron development;GO:0007254//JNK cascade;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0042752//regulation of circadian rhythm","K04440//c-Jun N-terminal kinase [EC:2.7.11.24]","XP_006143356.1//PREDICTED: mitogen-activated protein kinase 10 [Tupaia chinensis];XP_021162857.1//mitogen-activated protein kinase 10 isoform X1 [Fundulus heteroclitus];NP_001304998.1//mitogen-activated protein kinase 10 isoform 1x [Homo sapiens]","4;1//3;3//A2MP1"]
[50650,3629,3.27,1.64,-0.995594820879999,{"v":1.95399877456647e-06,"d":"1.95E-06"},"*",{"v":3.38592e-07,"d":"3.39E-07"},"ARHGEF3","GO:0005829//cytosol;GO:0005622//intracellular","GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005089//Rho guanyl-nucleotide exchange factor activity","GO:0007266//Rho protein signal transduction;GO:0043065//positive regulation of apoptotic process;GO:0035556//intracellular signal transduction;GO:0035023//regulation of Rho protein signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction","K20683//Rho guanine nucleotide exchange factor 3/8","XP_011229573.2//PREDICTED: rho guanine nucleotide exchange factor 3 isoform X1 [Ailuropoda melanoleuca];BAD92898.1//Rho guanine nucleotide exchange factor 3 variant, partial [Homo sapiens];XP_007982868.1//PREDICTED: rho guanine nucleotide exchange factor 3 isoform X1 [Chlorocebus sabaeus];NP_001122087.1//rho guanine nucleotide exchange factor 3 isoform 1 [Homo sapiens]","1//3;2//1"]
[196528,8619,3.98,2,-0.992768430768924,{"v":2.36874985756677e-16,"d":"2.37E-16"},"*",{"v":1.49919e-17,"d":"1.50E-17"},"ARID2","GO:0005654//nucleoplasm;GO:0005886//plasma membrane","GO:0046872//metal ion binding;GO:0003677//DNA binding","GO:0042592//homeostatic process;GO:0060982//coronary artery morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0030336//negative regulation of cell migration;GO:0048568//embryonic organ development;GO:0006337//nucleosome disassembly;GO:0003007//heart morphogenesis;GO:0060038//cardiac muscle cell proliferation;GO:0016569//covalent chromatin modification;GO:0008285//negative regulation of cell proliferation","K11765//AT-rich interactive domain-containing protein 2","NP_001334768.1//AT-rich interactive domain-containing protein 2 isoform 2 [Homo sapiens];NP_689854.2//AT-rich interactive domain-containing protein 2 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[8458,4860,7.72,3.9,-0.98512672351847,{"v":1.49824759181034e-17,"d":"1.50E-17"},"*",{"v":8.70398e-19,"d":"8.70E-19"},"TTF2","GO:0008023//transcription elongation factor complex;GO:0005681//spliceosomal complex;GO:0005829//cytosol","GO:0003677//DNA binding;GO:0005524//ATP binding;GO:0008270//zinc ion binding;GO:0004386//helicase activity;GO:0008094//DNA-dependent ATPase activity","GO:0006397//mRNA processing;GO:0006353//DNA-templated transcription, termination;GO:0006355//regulation of transcription, DNA-templated;GO:0006369//termination of RNA polymerase II transcription;GO:0008380//RNA splicing","K15173//transcription termination factor 2 [EC:3.6.4.-]","NP_003585.3//transcription termination factor 2 [Homo sapiens]","3//A2MP1"]
[9619,2946,0.81,0.41,-0.982297998266541,0.0606091441002737,"*",0.0263358,"ABCG1","GO:0009897//external side of plasma membrane;GO:0000139//Golgi membrane;GO:0005768//endosome;GO:0005887//integral component of plasma membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005739//mitochondrion;GO:0055037//recycling endosome;GO:0005886//plasma membrane","GO:0005524//ATP binding;GO:0015485//cholesterol binding;GO:0046982//protein heterodimerization activity;GO:0017127//cholesterol transporter activity;GO:0042803//protein homodimerization activity;GO:0046983//protein dimerization activity;GO:0005543//phospholipid binding;GO:0043531//ADP binding;GO:0019534//toxin transmembrane transporter activity;GO:0034041//sterol-transporting ATPase activity;GO:0034437//glycoprotein transporter activity;GO:0005548//phospholipid transporter activity","GO:0010875//positive regulation of cholesterol efflux;GO:0034436//glycoprotein transport;GO:0042987//amyloid precursor protein catabolic process;GO:0008203//cholesterol metabolic process;GO:0006355//regulation of transcription, DNA-templated;GO:0009720//detection of hormone stimulus;GO:0034374//low-density lipoprotein particle remodeling;GO:0010872//regulation of cholesterol esterification;GO:0033344//cholesterol efflux;GO:0010033//response to organic substance;GO:0042632//cholesterol homeostasis;GO:0055091//phospholipid homeostasis;GO:0055085//transmembrane transport;GO:0033993//response to lipid;GO:0010887//negative regulation of cholesterol storage;GO:0032367//intracellular cholesterol transport;GO:0010745//negative regulation of macrophage derived foam cell differentiation;GO:0034375//high-density lipoprotein particle remodeling;GO:0033700//phospholipid efflux;GO:0045542//positive regulation of cholesterol biosynthetic process;GO:0043691//reverse cholesterol transport","K05679//ATP-binding cassette, subfamily G (WHITE), member 1","NP_997512.1//ATP-binding cassette sub-family G member 1 isoform 7 [Homo sapiens];NP_997510.1//ATP-binding cassette sub-family G member 1 isoform 5 [Homo sapiens];NP_058198.2//ATP-binding cassette sub-family G member 1 isoform 2 [Homo sapiens];NP_997057.1//ATP-binding cassette sub-family G member 1 isoform 3 [Homo sapiens];NP_004906.3//ATP-binding cassette sub-family G member 1 isoform 4 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[54801,6279,12.33,6.25,-0.98024470485339,{"v":3.74542468248588e-35,"d":"3.75E-35"},"*",{"v":8.30024e-37,"d":"8.30E-37"},"HAUS6","GO:0005815//microtubule organizing center;GO:0005874//microtubule;GO:0070652//HAUS complex;GO:0005829//cytosol;GO:0005819//spindle;GO:0016607//nuclear speck;GO:0005813//centrosome","NA","GO:0010389//regulation of G2/M transition of mitotic cell cycle;GO:0097711//ciliary basal body-plasma membrane docking;GO:0007098//centrosome cycle;GO:0051225//spindle assembly;GO:0051301//cell division;GO:0000086//G2/M transition of mitotic cell cycle","K16589//HAUS augmin-like complex subunit 6","NP_001257819.1//HAUS augmin-like complex subunit 6 isoform 2 [Homo sapiens];NP_060115.3//HAUS augmin-like complex subunit 6 isoform 1 [Homo sapiens]","1//3;4"]
[9754,4962,1.04,0.53,-0.972519263577893,3.88547023774558E-3,"*",0.001225672,"STARD8","GO:0005925//focal adhesion;GO:0005829//cytosol","GO:0008289//lipid binding;GO:0005096//GTPase activator activity","GO:0007165//signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction","K20632//deleted in liver cancer protein","CAH18253.1//hypothetical protein [Homo sapiens];XP_005593880.2//PREDICTED: stAR-related lipid transfer protein 8 isoform X2 [Macaca fascicularis];NP_001135975.1//stAR-related lipid transfer protein 8 isoform a [Homo sapiens]","4;2//1"]
[8705,1704,0.47,0.24,-0.969626350956481,0.347927930807249,"*",0.211536,"B3GALT4","GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0008499//UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity;GO:0047915//ganglioside galactosyltransferase activity;GO:0008378//galactosyltransferase activity","GO:0006486//protein glycosylation;GO:0001574//ganglioside biosynthetic process","K00715//ganglioside galactosyltransferase [EC:2.4.1.62]","NP_003773.1//beta-1,3-galactosyltransferase 4 [Homo sapiens]","3//A2MP1"]
[1591,3134,191.48,97.78,-0.969582400711629,{"v":2.14276917473684e-266,"d":"2.14E-266"},"*",{"v":2.54868e-269,"d":"2.55E-269"},"CYP24A1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005886//plasma membrane","GO:0008403//25-hydroxycholecalciferol-24-hydroxylase activity;GO:0020037//heme binding;GO:0030342//1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity;GO:0005506//iron ion binding;GO:0016491//oxidoreductase activity","GO:0070561//vitamin D receptor signaling pathway;GO:0001649//osteoblast differentiation;GO:0006766//vitamin metabolic process;GO:0042369//vitamin D catabolic process;GO:0042359//vitamin D metabolic process;GO:0033280//response to vitamin D;GO:0055114//oxidation-reduction process","K07436//vitamin D3 24-hydroxylase [EC:1.14.15.16]","XP_009214176.2//1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial [Papio anubis];NP_001122387.1//1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial isoform 2 precursor [Homo sapiens]","4;1//3"]
[23683,5915,5.62,2.88,-0.964501318778614,{"v":4.67248812197309e-15,"d":"4.67E-15"},"*",{"v":3.26144e-16,"d":"3.26E-16"},"PRKD3","GO:0016020//membrane;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0004697//protein kinase C activity","GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0089700//protein kinase D signaling;GO:0030148//sphingolipid biosynthetic process;GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction","K06070//protein kinase D [EC:2.7.11.13]","NP_005804.1//serine/threonine-protein kinase D3 [Homo sapiens]",4]
[5016,2258,0.35,0.18,-0.959358015502654,0.347963759036145,"*",0.211536,"OVGP1","GO:0035805//egg coat;GO:0030133//transport vesicle;GO:0005829//cytosol;GO:0098595//perivitelline space;GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0008061//chitin binding;GO:0004568//chitinase activity","GO:0007565//female pregnancy;GO:0006032//chitin catabolic process;GO:2000360//negative regulation of binding of sperm to zona pellucida;GO:0005975//carbohydrate metabolic process;GO:0007339//binding of sperm to zona pellucida","K17526//oviduct-specific glycoprotein","NP_002548.3//oviduct-specific glycoprotein precursor [Homo sapiens]","3//A2MP1"]
[146227,2824,1.38,0.71,-0.958777337273487,0.0112326043333928,"*",0.00393992,"BEAN1","GO:0016021//integral component of membrane","NA","NA","K17595//spermatogenesis-associated protein 2;K19324//protein BEAN1","XP_017715720.1//PREDICTED: protein BEAN1 isoform X1 [Rhinopithecus bieti];NP_001171491.1//protein BEAN1 isoform 1 [Homo sapiens];XP_016785459.1//PREDICTED: protein BEAN1 isoform X2 [Pan troglodytes]","4;3//A2MP1;2//1"]
[253461,8295,11.38,5.87,-0.95506814919653,{"v":3.15559205581395e-40,"d":"3.16E-40"},"*",{"v":5.94612e-42,"d":"5.95E-42"},"ZBTB38","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0072562//blood microparticle;GO:0005694//chromosome","GO:0046872//metal ion binding;GO:0003700//DNA binding transcription factor activity;GO:0042803//protein homodimerization activity;GO:0008327//methyl-CpG binding;GO:0003676//nucleic acid binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006275//regulation of DNA replication;GO:0006351//transcription, DNA-templated;GO:0006974//cellular response to DNA damage stimulus","K10510//zinc finger and BTB domain-containing protein 38","XP_011813485.1//PREDICTED: zinc finger and BTB domain-containing protein 38 isoform X1 [Colobus angolensis palliatus];XP_011510909.1//PREDICTED: zinc finger and BTB domain-containing protein 38 isoform X1 [Homo sapiens]","1//3;2//1"]
[23767,3830,1.8,0.93,-0.952694285221643,0.000909519850214302,"*",0.000252404,"FLRT3","GO:0005615//extracellular space;GO:0044295//axonal growth cone;GO:0005925//focal adhesion;GO:0005737//cytoplasm;GO:0097060//synaptic membrane;GO:0005578//proteinaceous extracellular matrix;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0016021//integral component of membrane;GO:0043679//axon terminus;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane","GO:0005057//signal transducer activity, downstream of receptor;GO:0004860//protein kinase inhibitor activity;GO:0030674//protein binding, bridging;GO:0045499//chemorepellent activity;GO:0042803//protein homodimerization activity;GO:0005104//fibroblast growth factor receptor binding","GO:0048678//response to axon injury;GO:0007507//heart development;GO:0046426//negative regulation of JAK-STAT cascade;GO:0003345//proepicardium cell migration involved in pericardium morphogenesis;GO:0051965//positive regulation of synapse assembly;GO:0007416//synapse assembly;GO:0006469//negative regulation of protein kinase activity;GO:1990138//neuron projection extension;GO:0060322//head development;GO:0098742//cell-cell adhesion via plasma-membrane adhesion molecules;GO:0031175//neuron projection development;GO:0019221//cytokine-mediated signaling pathway;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0007411//axon guidance;GO:0048598//embryonic morphogenesis","K16362//leucine-rich repeat transmembrane protein FLRT","NP_037413.1//leucine-rich repeat transmembrane protein FLRT3 precursor [Homo sapiens]","3//A2MP1;2//1"]
[117583,7871,0.56,0.29,-0.949373926930032,0.011032446104245,"*",0.0038559,"PARD3B","GO:0016020//membrane;GO:0012505//endomembrane system;GO:0043234//protein complex;GO:0030054//cell junction;GO:0005923//bicellular tight junction","NA","GO:0051301//cell division;GO:0007049//cell cycle","K04237//partitioning defective protein 3","NP_689739.4//partitioning defective 3 homolog B isoform Par3Lb [Homo sapiens];NP_995585.2//partitioning defective 3 homolog B isoform 4 [Homo sapiens];NP_476518.4//partitioning defective 3 homolog B isoform Par3Lc [Homo sapiens];NP_001289698.1//partitioning defective 3 homolog B isoform Par3La [Homo sapiens]","6;1//3;3//A2MP1;5"]
[170691,6358,0.25,0.13,-0.943416471633632,0.188734445401823,"*",0.0998258,"ADAMTS17","GO:0005578//proteinaceous extracellular matrix","GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding;GO:0003676//nucleic acid binding","NA","K08631//a disintegrin and metalloproteinase with thrombospondin motifs 17 [EC:3.4.24.-]","NP_620688.2//A disintegrin and metalloproteinase with thrombospondin motifs 17 preproprotein [Homo sapiens]","3//A2MP1"]
[2033,8761,10.11,5.26,-0.942648292610712,{"v":1.49527453169231e-37,"d":"1.50E-37"},"*",{"v":3.04222e-39,"d":"3.04E-39"},"EP300","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription factor complex;GO:0005829//cytosol;GO:0000123//histone acetyltransferase complex;GO:0005694//chromosome","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0140068//histone crotonyltransferase activity;GO:0097157//pre-mRNA intronic binding;GO:0031490//chromatin DNA binding;GO:0061920//protein propionyltransferase activity;GO:0004468//lysine N-acetyltransferase activity, acting on acetyl phosphate as donor;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0050681//androgen receptor binding;GO:0003712//transcription cofactor activity;GO:0008270//zinc ion binding;GO:0001102//RNA polymerase II activating transcription factor binding;GO:0016407//acetyltransferase activity;GO:0033613//activating transcription factor binding;GO:0097677//STAT family protein binding;GO:0004402//histone acetyltransferase activity;GO:0002039//p53 binding;GO:0140069//histone butyryltransferase activity;GO:0003713//transcription coactivator activity;GO:0003684//damaged DNA binding;GO:0008022//protein C-terminus binding;GO:0008013//beta-catenin binding","GO:0043969//histone H2B acetylation;GO:0140066//peptidyl-lysine crotonylation;GO:0043627//response to estrogen;GO:0090043//regulation of tubulin deacetylation;GO:0032092//positive regulation of protein binding;GO:0043923//positive regulation by host of viral transcription;GO:0140067//peptidyl-lysine butyrylation;GO:0034644//cellular response to UV;GO:0001756//somitogenesis;GO:0007507//heart development;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0001666//response to hypoxia;GO:0006915//apoptotic process;GO:1904837//beta-catenin-TCF complex assembly;GO:0010742//macrophage derived foam cell differentiation;GO:0007519//skeletal muscle tissue development;GO:0030324//lung development;GO:0045815//positive regulation of gene expression, epigenetic;GO:0006355//regulation of transcription, DNA-templated;GO:0018076//N-terminal peptidyl-lysine acetylation;GO:0060765//regulation of androgen receptor signaling pathway;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0043967//histone H4 acetylation;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0030220//platelet formation;GO:0030183//B cell differentiation;GO:0031648//protein destabilization;GO:0007623//circadian rhythm;GO:0035855//megakaryocyte development;GO:0006990//positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response;GO:0009887//animal organ morphogenesis;GO:0045444//fat cell differentiation;GO:0061921//peptidyl-lysine propionylation;GO:0050821//protein stabilization","K04498//E1A/CREB-binding protein [EC:2.3.1.48]","NP_001420.2//histone acetyltransferase p300 [Homo sapiens]","3//A2MP1"]
[440672,3650,5.46,2.85,-0.937939031867748,{"v":5.79397588985212e-09,"d":"5.79E-09"},"*",{"v":7.1128e-10,"d":"7.11E-10"},"NUDT4B","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005737//cytoplasm","GO:0052841//inositol bisdiphosphate tetrakisphosphate diphosphatase activity;GO:0050072//m7G(5')pppN diphosphatase activity;GO:0052844//inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity;GO:0034431//bis(5'-adenosyl)-hexaphosphatase activity;GO:0016787//hydrolase activity;GO:0008486//diphosphoinositol-polyphosphate diphosphatase activity;GO:0052842//inositol diphosphate pentakisphosphate diphosphatase activity;GO:0052843//inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity;GO:0030515//snoRNA binding;GO:0052845//inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity;GO:0052848//inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity;GO:0052846//inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity;GO:0046872//metal ion binding;GO:0000298//endopolyphosphatase activity;GO:0034432//bis(5'-adenosyl)-pentaphosphatase activity;GO:0052847//inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity;GO:0052840//inositol diphosphate tetrakisphosphate diphosphatase activity","GO:0019935//cyclic-nucleotide-mediated signaling;GO:0046907//intracellular transport;GO:0071543//diphosphoinositol polyphosphate metabolic process;GO:0009187//cyclic nucleotide metabolic process;GO:1901907//diadenosine pentaphosphate catabolic process;GO:0019722//calcium-mediated signaling;GO:0035556//intracellular signal transduction;GO:0046831//regulation of RNA export from nucleus;GO:1901911//adenosine 5'-(hexahydrogen pentaphosphate) catabolic process;GO:1901909//diadenosine hexaphosphate catabolic process;GO:0043647//inositol phosphate metabolic process","K07766//diphosphoinositol-polyphosphate diphosphatase [EC:3.6.1.52]","XP_011743007.1//PREDICTED: LOW QUALITY PROTEIN: diphosphoinositol polyphosphate phosphohydrolase 2 [Macaca nemestrina]","1//3"]
[11107,5170,0.44,0.23,-0.935869662580284,0.0606178774063401,"*",0.0263358,"PRDM5","NA","GO:0046872//metal ion binding;GO:0000976//transcription regulatory region sequence-specific DNA binding","NA","K09228//KRAB domain-containing zinc finger protein","NP_001179836.2//PR domain zinc finger protein 5 [Bos taurus];XP_003221822.2//PREDICTED: PR domain zinc finger protein 5 isoform X2 [Anolis carolinensis];XP_006866344.1//PREDICTED: PR domain zinc finger protein 5-like isoform X3 [Chrysochloris asiatica]","1//3;3//A2MP1"]
[388335,2698,2.12,1.11,-0.933504588213093,2.46466970244509E-3,"*",0.000744616,"TMEM220","NA","NA","NA","K07560//D-tyrosyl-tRNA(Tyr) deacylase [EC:3.1.-.-];K17985//activating molecule in BECN1-regulated autophagy protein 1;K04613//vomeronasal 2 receptor;K01064//wingless-type MMTV integration site family, member 9","XP_011828567.1//PREDICTED: transmembrane protein 220 isoform X3 [Mandrillus leucophaeus];XP_011828566.1//PREDICTED: transmembrane protein 220 isoform X2 [Mandrillus leucophaeus];XP_016880106.1//PREDICTED: transmembrane protein 220 isoform X2 [Homo sapiens];XP_011828568.1//PREDICTED: transmembrane protein 220 isoform X4 [Mandrillus leucophaeus]","1//3;2//1"]
[55284,8426,3.47,1.82,-0.930997212379565,0.0273391738216868,"*",0.01065396,"UBE2W","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm","GO:0061630//ubiquitin protein ligase activity;GO:0005524//ATP binding;GO:0031625//ubiquitin protein ligase binding;GO:0004842//ubiquitin-protein transferase activity","GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0006281//DNA repair;GO:0006513//protein monoubiquitination;GO:0016567//protein ubiquitination;GO:0006515//protein quality control for misfolded or incompletely synthesized proteins;GO:0070979//protein K11-linked ubiquitination;GO:0071218//cellular response to misfolded protein","K10688//ubiquitin-conjugating enzyme E2 W [EC:2.3.2.25]","NP_001257944.1//ubiquitin-conjugating enzyme E2 W isoform 3 [Homo sapiens];NP_060769.4//ubiquitin-conjugating enzyme E2 W isoform 2 [Homo sapiens];NP_001001481.2//ubiquitin-conjugating enzyme E2 W isoform 1 [Homo sapiens]","4;1//3;2//1"]
[6653,10973,0.38,0.2,-0.925999418556223,0.0153838050569162,"*",5.58378E-3,"SORL1","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0010008//endosome membrane;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0034362//low-density lipoprotein particle;GO:0005802//trans-Golgi network;GO:0000139//Golgi membrane;GO:0005768//endosome;GO:0005887//integral component of plasma membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0031985//Golgi cisterna;GO:0055037//recycling endosome;GO:0005641//nuclear envelope lumen;GO:0005769//early endosome","GO:0005041//low-density lipoprotein receptor activity;GO:0001540//amyloid-beta binding;GO:0030169//low-density lipoprotein particle binding;GO:0030306//ADP-ribosylation factor binding;GO:0004888//transmembrane signaling receptor activity","GO:1902955//positive regulation of early endosome to recycling endosome transport;GO:1901215//negative regulation of neuron death;GO:1902430//negative regulation of amyloid-beta formation;GO:1902771//positive regulation of choline O-acetyltransferase activity;GO:0008203//cholesterol metabolic process;GO:1902966//positive regulation of protein localization to early endosome;GO:1902948//negative regulation of tau-protein kinase activity;GO:0043407//negative regulation of MAP kinase activity;GO:0006869//lipid transport;GO:0032460//negative regulation of protein oligomerization;GO:0044267//cellular protein metabolic process;GO:0045053//protein retention in Golgi apparatus;GO:0032091//negative regulation of protein binding;GO:1902997//negative regulation of neurofibrillary tangle assembly;GO:0006810//transport;GO:0006605//protein targeting;GO:0050768//negative regulation of neurogenesis;GO:0006622//protein targeting to lysosome;GO:1902953//positive regulation of ER to Golgi vesicle-mediated transport;GO:2001137//positive regulation of endocytic recycling;GO:0070863//positive regulation of protein exit from endoplasmic reticulum;GO:1902960//negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process;GO:0006898//receptor-mediated endocytosis;GO:0045732//positive regulation of protein catabolic process;GO:0000042//protein targeting to Golgi;GO:0051604//protein maturation;GO:0006892//post-Golgi vesicle-mediated transport;GO:1902963//negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process;GO:0014910//regulation of smooth muscle cell migration","K04550//low-density lipoprotein receptor-related protein 1 (alpha-2-macroglobulin receptor)","NP_003096.1//sortilin-related receptor preproprotein [Homo sapiens]",5]
[148014,859,0.19,0.1,-0.925999418556223,0.729690549511448,"*",0.626454,"TTC9B","NA","NA","NA","K09572//FK506-binding protein 6 [EC:5.2.1.8];K05864//peptidyl-prolyl isomerase D [EC:5.2.1.8];K20097//FK506-binding protein-like","NP_689692.2//tetratricopeptide repeat protein 9B [Homo sapiens]",5]
[51655,1740,0.53,0.28,-0.920565532505595,0.289269245515165,"*",0.1683752,"RASD1","GO:0016020//membrane;GO:0016529//sarcoplasmic reticulum","GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0007165//signal transduction","K07843//RAS, dexamethasone-induced Ras-related protein 1","XP_020035893.1//dexamethasone-induced Ras-related protein 1 [Castor canadensis];XP_006042902.1//PREDICTED: glutenin, high molecular weight subunit DX5 isoform X1 [Bubalus bubalis]","4;1//3"]
[342908,1868,0.17,0.09,-0.917537839808027,0.610799981836529,"*",0.454716,"ZNF404","GO:0005634//nucleus;GO:0005622//intracellular","GO:0046872//metal ion binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","XP_004401072.1//PREDICTED: zinc finger protein 404 [Odobenus rosmarus divergens]","2//1"]
[6884,577,4.75,2.52,-0.914503779718394,0.0746664907360761,"*",0.0334022,"TAF13","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005669//transcription factor TFIID complex","GO:0003743//translation initiation factor activity;GO:0003677//DNA binding;GO:0008022//protein C-terminus binding;GO:0003712//transcription cofactor activity;GO:0046982//protein heterodimerization activity;GO:0003700//DNA binding transcription factor activity","GO:0006368//transcription elongation from RNA polymerase II promoter;GO:1901796//regulation of signal transduction by p53 class mediator;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0042795//snRNA transcription from RNA polymerase II promoter;GO:0006355//regulation of transcription, DNA-templated;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006352//DNA-templated transcription, initiation;GO:0006366//transcription from RNA polymerase II promoter","K03127//transcription initiation factor TFIID subunit 13","XP_020734151.1//transcription initiation factor TFIID subunit 13 [Odocoileus virginianus texanus]","3//A2MP1"]
[140735,1522,28.71,15.26,-0.911798368372651,{"v":1.72340757894737E-17,"d":"1.72E-17"},"*",{"v":1.00444e-18,"d":"1.00E-18"},"DYNLL2","NA","NA","NA","K10418//dynein light chain LC8-type","EAW94483.1//dynein, light chain, LC8-type 2, isoform CRA_a, partial [Homo sapiens]","2//1"]
[90075,2601,2.42,1.29,-0.90763598185134,0.00254056224333815,"*",0.00076993,"ZNF30","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","NP_001092907.1//zinc finger protein 30 isoform a [Homo sapiens];NP_919306.2//zinc finger protein 30 isoform b [Homo sapiens]","1//3;2//1"]
[1188,2174,0.15,0.08,-0.906890595608519,0.436583569989645,"*",0.290336,"CLCNKB","GO:0005887//integral component of plasma membrane;GO:0034707//chloride channel complex;GO:0005886//plasma membrane","GO:0046872//metal ion binding;GO:0005247//voltage-gated chloride channel activity","GO:0006810//transport;GO:0034220//ion transmembrane transport;GO:0007588//excretion;GO:1902476//chloride transmembrane transport","K05017//chloride channel Ka;K05018//chloride channel Kb","XP_016810262.1//PREDICTED: chloride channel protein ClC-Kb isoform X1 [Pan troglodytes];NP_001159417.2//chloride channel protein ClC-Kb isoform 2 [Homo sapiens]","4;2//1"]
[8671,7693,0.75,0.4,-0.906890595608519,0.00416746708965517,"*",1.32402E-3,"SLC4A4","GO:0070062//extracellular exosome;GO:0016323//basolateral plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0008510//sodium:bicarbonate symporter activity;GO:0005452//inorganic anion exchanger activity;GO:0042802//identical protein binding","GO:0006810//transport;GO:0015701//bicarbonate transport;GO:0051453//regulation of intracellular pH;GO:0006814//sodium ion transport","K13575//solute carrier family 4 (sodium bicarbonate cotransporter), member 4","XP_018881269.1//PREDICTED: electrogenic sodium bicarbonate cotransporter 1 isoform X1 [Gorilla gorilla gorilla];NP_003750.1//electrogenic sodium bicarbonate cotransporter 1 isoform 2 [Homo sapiens];NP_001128214.1//electrogenic sodium bicarbonate cotransporter 1 isoform 3 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[4488,2224,5.26,2.81,-0.904492669071376,{"v":2.53777993275293e-05,"d":"2.54E-05"},"*",{"v":5.29194e-06,"d":"5.29E-06"},"MSX2","GO:0005634//nucleus;GO:0005829//cytosol;GO:0016607//nuclear speck","GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003712//transcription cofactor activity;GO:0044212//transcription regulatory region DNA binding;GO:0008134//transcription factor binding;GO:0001227//transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding","GO:0003148//outflow tract septum morphogenesis;GO:0001649//osteoblast differentiation;GO:0060364//frontal suture morphogenesis;GO:0090427//activation of meiosis;GO:0030513//positive regulation of BMP signaling pathway;GO:0070166//enamel mineralization;GO:0060444//branching involved in mammary gland duct morphogenesis;GO:0035880//embryonic nail plate morphogenesis;GO:0061312//BMP signaling pathway involved in heart development;GO:0045617//negative regulation of keratinocyte differentiation;GO:0008285//negative regulation of cell proliferation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0032792//negative regulation of CREB transcription factor activity;GO:0035116//embryonic hindlimb morphogenesis;GO:0045599//negative regulation of fat cell differentiation;GO:0043066//negative regulation of apoptotic process;GO:0060363//cranial suture morphogenesis;GO:0007275//multicellular organism development;GO:0009952//anterior/posterior pattern specification;GO:2000678//negative regulation of transcription regulatory region DNA binding;GO:0003198//epithelial to mesenchymal transition involved in endocardial cushion formation;GO:0006355//regulation of transcription, DNA-templated;GO:0002063//chondrocyte development;GO:0023019//signal transduction involved in regulation of gene expression;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0060346//bone trabecula formation;GO:0003416//endochondral bone growth;GO:2001055//positive regulation of mesenchymal cell apoptotic process;GO:0006351//transcription, DNA-templated;GO:0045669//positive regulation of osteoblast differentiation;GO:0035115//embryonic forelimb morphogenesis;GO:0048863//stem cell differentiation;GO:0035313//wound healing, spreading of epidermal cells;GO:0051795//positive regulation of timing of catagen;GO:0071392//cellular response to estradiol stimulus;GO:0002076//osteoblast development","K09341//homeobox protein MSX","NP_002440.2//homeobox protein MSX-2 [Homo sapiens]",4]
[79983,3949,1.83,0.98,-0.900989994168835,1.34060975731122E-3,"*",0.000384542,"POF1B","GO:0005884//actin filament;GO:0005923//bicellular tight junction;GO:0005912//adherens junction;GO:0030057//desmosome","GO:0051015//actin filament binding","GO:0007015//actin filament organization;GO:0070830//bicellular tight junction assembly;GO:0030036//actin cytoskeleton organization;GO:0003382//epithelial cell morphogenesis","K17388//Rho-associated protein kinase 2 [EC:2.7.11.1]","XP_007990383.1//PREDICTED: protein POF1B isoform X2 [Chlorocebus sabaeus];XP_007990382.1//PREDICTED: protein POF1B isoform X1 [Chlorocebus sabaeus]","1//3;3//A2MP1"]
[84254,3488,15.27,8.19,-0.898764705155843,{"v":6.31495141828255e-21,"d":"6.31E-21"},"*",{"v":2.85426e-22,"d":"2.85E-22"},"CAMKK1","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0004683//calmodulin-dependent protein kinase activity;GO:0005516//calmodulin binding","GO:0018107//peptidyl-threonine phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0045860//positive regulation of protein kinase activity;GO:0035556//intracellular signal transduction","K00908//calcium/calmodulin-dependent protein kinase kinase 1 [EC:2.7.11.17]","XP_011522333.2//PREDICTED: calcium/calmodulin-dependent protein kinase kinase 1 isoform X1 [Homo sapiens];NP_757343.2//calcium/calmodulin-dependent protein kinase kinase 1 isoform c [Homo sapiens]","1//3;2//1"]
[1836,8082,4.86,2.61,-0.896906507035897,{"v":7.77347528312679e-16,"d":"7.77E-16"},"*",{"v":5.10478E-17,"d":"5.10E-17"},"SLC26A2","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005887//integral component of plasma membrane;GO:0016324//apical plasma membrane;GO:0031528//microvillus membrane;GO:0005886//plasma membrane","GO:0019531//oxalate transmembrane transporter activity;GO:0015301//anion:anion antiporter activity;GO:0015116//sulfate transmembrane transporter activity;GO:0005254//chloride channel activity;GO:0008271//secondary active sulfate transmembrane transporter activity;GO:0015106//bicarbonate transmembrane transporter activity","GO:0051453//regulation of intracellular pH;GO:0001503//ossification;GO:0006811//ion transport;GO:0015701//bicarbonate transport;GO:0050428//3'-phosphoadenosine 5'-phosphosulfate biosynthetic process;GO:1902358//sulfate transmembrane transport;GO:1902476//chloride transmembrane transport;GO:0042391//regulation of membrane potential","K14701//solute carrier family 26 (sulfate anion transporter), member 2","XP_016809512.1//PREDICTED: sulfate transporter isoform X1 [Pan troglodytes]","3//A2MP1"]
[342371,7886,6.77,3.64,-0.8952173833763,{"v":4.58780489703808e-21,"d":"4.59E-21"},"*",{"v":2.03628E-22,"d":"2.04E-22"},"ATXN1L","GO:0030425//dendrite;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus","GO:0003723//RNA binding;GO:0003677//DNA binding","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:1902035//positive regulation of hematopoietic stem cell proliferation;GO:0030198//extracellular matrix organization;GO:0006351//transcription, DNA-templated;GO:0048286//lung alveolus development","K21644//HMG box transcription factor 1;K14718//solute carrier family 39 (zinc transporter), member 12","NP_001131147.1//ataxin-1-like [Homo sapiens]","3//A2MP1"]
[9712,4676,4.68,2.52,-0.893084796083488,{"v":4.81837069551778E-9,"d":"4.82E-09"},"*",{"v":5.8548e-10,"d":"5.85E-10"},"USP6NL","GO:0012505//endomembrane system;GO:0032588//trans-Golgi network membrane;GO:0005829//cytosol;GO:0031410//cytoplasmic vesicle;GO:0005886//plasma membrane","GO:0017137//Rab GTPase binding;GO:0005096//GTPase activator activity","GO:0035526//retrograde transport, plasma membrane to Golgi;GO:1903358//regulation of Golgi organization;GO:0090630//activation of GTPase activity;GO:0019068//virion assembly;GO:0043547//positive regulation of GTPase activity;GO:0007030//Golgi organization;GO:0006886//intracellular protein transport;GO:0031338//regulation of vesicle fusion;GO:0048227//plasma membrane to endosome transport","K20133//USP6 N-terminal-like protein","NP_055503.1//USP6 N-terminal-like protein isoform 1 [Homo sapiens];NP_001073960.1//USP6 N-terminal-like protein isoform 2 [Homo sapiens]","3//A2MP1"]
[677,3217,140.18,75.56,-0.891585922544806,{"v":1.05404439E-170,"d":"1.05E-170"},"*",{"v":2.6394e-173,"d":"2.64E-173"},"ZFP36L1","GO:0005634//nucleus;GO:0030529//intracellular ribonucleoprotein complex;GO:0005829//cytosol;GO:0000932//P-body;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0071889//14-3-3 protein binding;GO:0035925//mRNA 3'-UTR AU-rich region binding;GO:0003700//DNA binding transcription factor activity","GO:0072091//regulation of stem cell proliferation;GO:0038066//p38MAPK cascade;GO:0010837//regulation of keratinocyte proliferation;GO:0043491//protein kinase B signaling;GO:0071356//cellular response to tumor necrosis factor;GO:1900153//positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0070371//ERK1 and ERK2 cascade;GO:0051028//mRNA transport;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:1902172//regulation of keratinocyte apoptotic process;GO:0060712//spongiotrophoblast layer development;GO:0021915//neural tube development;GO:0001570//vasculogenesis;GO:0031086//nuclear-transcribed mRNA catabolic process, deadenylation-independent decay;GO:0045647//negative regulation of erythrocyte differentiation;GO:0097403//cellular response to raffinose;GO:0009611//response to wounding;GO:0045577//regulation of B cell differentiation;GO:0007507//heart development;GO:0045600//positive regulation of fat cell differentiation;GO:0045661//regulation of myoblast differentiation;GO:1901991//negative regulation of mitotic cell cycle phase transition;GO:0031440//regulation of mRNA 3'-end processing;GO:0035264//multicellular organism growth;GO:0006915//apoptotic process;GO:0071375//cellular response to peptide hormone stimulus;GO:1904582//positive regulation of intracellular mRNA localization;GO:0071472//cellular response to salt stress;GO:0071456//cellular response to hypoxia;GO:0010468//regulation of gene expression;GO:0048382//mesendoderm development;GO:0071385//cellular response to glucocorticoid stimulus;GO:0033077//T cell differentiation in thymus;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0071320//cellular response to cAMP;GO:0060710//chorio-allantoic fusion;GO:0008283//cell proliferation;GO:0043488//regulation of mRNA stability;GO:0006397//mRNA processing;GO:0000165//MAPK cascade;GO:1904628//cellular response to phorbol 13-acetate 12-myristate;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0032869//cellular response to insulin stimulus;GO:0061158//3'-UTR-mediated mRNA destabilization;GO:0045616//regulation of keratinocyte differentiation;GO:0003342//proepicardium development;GO:0045657//positive regulation of monocyte differentiation","K18753//butyrate response factor","NP_001231630.1//mRNA decay activator protein ZFP36L1 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[285331,3180,2.37,1.28,-0.888743248898259,0.000965021746858169,"*",0.000269196,"CCDC66","NA","NA","NA","K16771//centrosome and spindle pole-associated protein 1;K18730//PERQ amino acid-rich with GYF domain-containing protein;K18626//trichohyalin","NP_001340076.1//coiled-coil domain-containing protein 66 isoform 3 [Homo sapiens];NP_001340083.1//coiled-coil domain-containing protein 66 isoform 8 [Homo sapiens];NP_001340084.1//coiled-coil domain-containing protein 66 isoform 9 [Homo sapiens];NP_001340078.1//coiled-coil domain-containing protein 66 isoform 5 [Homo sapiens];NP_001135419.1//coiled-coil domain-containing protein 66 isoform 1 [Homo sapiens];NP_001340077.1//coiled-coil domain-containing protein 66 isoform 4 [Homo sapiens];XP_016796836.1//PREDICTED: coiled-coil domain-containing protein 66 isoform X5 [Pan troglodytes];NP_001340080.1//coiled-coil domain-containing protein 66 isoform 7 [Homo sapiens];NP_001340079.1//coiled-coil domain-containing protein 66 isoform 6 [Homo sapiens];NP_001012524.4//coiled-coil domain-containing protein 66 isoform 2 [Homo sapiens]","1//3;2//1;5"]
[22866,5717,1.35,0.73,-0.886991038170814,0.00115475456201636,"*",0.000326966,"CNKSR2","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0014069//postsynaptic density;GO:0005737//cytoplasm;GO:0045211//postsynaptic membrane;GO:0043025//neuronal cell body;GO:0043005//neuron projection","GO:0016301//kinase activity;GO:0042802//identical protein binding","GO:0009966//regulation of signal transduction","K17536//connector enhancer of kinase suppressor of Ras 2","XP_016884847.1//PREDICTED: connector enhancer of kinase suppressor of ras 2 isoform X3 [Homo sapiens];NP_055742.2//connector enhancer of kinase suppressor of ras 2 isoform 1 [Homo sapiens];NP_001317699.1//connector enhancer of kinase suppressor of ras 2 isoform 5 [Homo sapiens];NP_001317701.1//connector enhancer of kinase suppressor of ras 2 isoform 7 [Homo sapiens];XP_011543773.1//PREDICTED: connector enhancer of kinase suppressor of ras 2 isoform X1 [Homo sapiens];NP_001162118.1//connector enhancer of kinase suppressor of ras 2 isoform 2 [Homo sapiens];XP_011543774.1//PREDICTED: connector enhancer of kinase suppressor of ras 2 isoform X2 [Homo sapiens]","1//3;4;2//1"]
[126393,1480,1.31,0.71,-0.883675882032768,0.146536121980886,"*",0.0739102,"HSPB6","GO:0005634//nucleus;GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0005212//structural constituent of eye lens;GO:0051082//unfolded protein binding;GO:0051087//chaperone binding;GO:0042803//protein homodimerization activity","GO:0006937//regulation of muscle contraction;GO:0010667//negative regulation of cardiac muscle cell apoptotic process;GO:0045766//positive regulation of angiogenesis;GO:0061077//chaperone-mediated protein folding","K09545//heat shock protein beta-6","XP_018871137.1//PREDICTED: heat shock protein beta-6 [Gorilla gorilla gorilla]","2//1"]
[102,5030,20.91,11.35,-0.881500764411302,{"v":3.81031677793103e-41,"d":"3.81E-41"},"*",{"v":6.91744e-43,"d":"6.92E-43"},"ADAM10","GO:0016020//membrane;GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0097038//perinuclear endoplasmic reticulum;GO:0097197//tetraspanin-enriched microdomain;GO:0005737//cytoplasm;GO:0000139//Golgi membrane;GO:0005798//Golgi-associated vesicle;GO:0016021//integral component of membrane;GO:0070821//tertiary granule membrane;GO:0005886//plasma membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005925//focal adhesion;GO:0014069//postsynaptic density;GO:0009986//cell surface;GO:0005794//Golgi apparatus;GO:0035579//specific granule membrane","GO:0004175//endopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0005102//receptor binding;GO:0042803//protein homodimerization activity;GO:0019901//protein kinase binding;GO:0046872//metal ion binding;GO:0005178//integrin binding;GO:0008237//metallopeptidase activity;GO:0017124//SH3 domain binding","GO:0043687//post-translational protein modification;GO:0010820//positive regulation of T cell chemotaxis;GO:0006509//membrane protein ectodomain proteolysis;GO:0051089//constitutive protein ectodomain proteolysis;GO:0030335//positive regulation of cell migration;GO:0007162//negative regulation of cell adhesion;GO:0030307//positive regulation of cell growth;GO:0044267//cellular protein metabolic process;GO:0016485//protein processing;GO:0043312//neutrophil degranulation;GO:0007229//integrin-mediated signaling pathway;GO:0006468//protein phosphorylation;GO:0007267//cell-cell signaling;GO:0048013//ephrin receptor signaling pathway;GO:0001701//in utero embryonic development;GO:0022617//extracellular matrix disassembly;GO:0034612//response to tumor necrosis factor;GO:0007220//Notch receptor processing;GO:0007219//Notch signaling pathway;GO:0051088//PMA-inducible membrane protein ectodomain proteolysis;GO:0042117//monocyte activation;GO:0008284//positive regulation of cell proliferation","K06704//disintegrin and metalloproteinase domain-containing protein 10 [EC:3.4.24.81]","NP_001307499.1//disintegrin and metalloproteinase domain-containing protein 10 isoform 2 precursor [Homo sapiens];NP_001101.1//disintegrin and metalloproteinase domain-containing protein 10 isoform 1 preproprotein [Homo sapiens]","1//3;3//A2MP1"]
[11215,9926,2.48,1.35,-0.877380713336044,{"v":4.37920457142857e-10,"d":"4.38E-10"},"*",{"v":4.7016e-11,"d":"4.70E-11"},"AKAP11","GO:0005815//microtubule organizing center;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005777//peroxisome;GO:0005886//plasma membrane","GO:0051018//protein kinase A binding;GO:0016301//kinase activity;GO:0008157//protein phosphatase 1 binding","GO:0010738//regulation of protein kinase A signaling;GO:0035556//intracellular signal transduction","K16527//A-kinase anchor protein 11","NP_057332.1//A-kinase anchor protein 11 [Homo sapiens]","3//A2MP1"]
[29104,995,4.4,2.4,-0.874469117916141,0.0168875156775183,"*",0.00620252,"N6AMT1","GO:0043234//protein complex;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0008757//S-adenosylmethionine-dependent methyltransferase activity;GO:0008168//methyltransferase activity;GO:0008276//protein methyltransferase activity;GO:0003676//nucleic acid binding","GO:0006415//translational termination;GO:0030307//positive regulation of cell growth;GO:0032259//methylation","K19589//release factor glutamine methyltransferase [EC:2.1.1.297]","NP_037372.4//hemK methyltransferase family member 2 isoform 1 [Homo sapiens];NP_877426.4//hemK methyltransferase family member 2 isoform 2 [Homo sapiens]","4;5"]
[154881,5051,3.06,1.67,-0.8736835502186,{"v":1.59612348533724E-6,"d":"1.60E-06"},"*",{"v":2.72582e-07,"d":"2.73E-07"},"KCTD7","GO:0005829//cytosol;GO:0005886//plasma membrane","NA","GO:0043687//post-translational protein modification;GO:0051260//protein homooligomerization","K21917//BTB/POZ domain-containing protein KCTD7/14","NP_694578.1//BTB/POZ domain-containing protein KCTD7 isoform 1 [Homo sapiens];XP_011787657.1//PREDICTED: BTB/POZ domain-containing protein KCTD7 isoform X1 [Colobus angolensis palliatus]","4;2//1"]
[3221,1867,9.5,5.2,-0.869415890189856,{"v":3.10115430806846e-06,"d":"3.10E-06"},"*",{"v":5.55816e-07,"d":"5.56E-07"},"HOXC4","GO:0005634//nucleus","GO:0071837//HMG box domain binding;GO:0001205//transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0009952//anterior/posterior pattern specification;GO:0007275//multicellular organism development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0048562//embryonic organ morphogenesis;GO:0051216//cartilage development","K09304//homeobox protein HoxA/B/C/D4","XP_017801399.2//homeobox protein Hox-C4 isoform X1 [Papio anubis];XP_016778776.1//PREDICTED: homeobox protein Hox-C4 isoform X1 [Pan troglodytes]","2//1;5"]
[1789,4224,4.52,2.48,-0.865982652028312,{"v":5.14613203243243e-08,"d":"5.15E-08"},"*",{"v":7.15188e-09,"d":"7.15E-09"},"DNMT3B","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0042826//histone deacetylase binding;GO:0003682//chromatin binding;GO:0003886//DNA (cytosine-5-)-methyltransferase activity;GO:0009008//DNA-methyltransferase activity","GO:0010468//regulation of gene expression;GO:0045666//positive regulation of neuron differentiation;GO:0009636//response to toxic substance;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0032355//response to estradiol;GO:0031000//response to caffeine;GO:0051573//negative regulation of histone H3-K9 methylation;GO:0033189//response to vitamin A;GO:0051571//positive regulation of histone H3-K4 methylation;GO:0042493//response to drug;GO:0010212//response to ionizing radiation;GO:0014823//response to activity;GO:0006306//DNA methylation;GO:0010628//positive regulation of gene expression;GO:0071549//cellular response to dexamethasone stimulus;GO:0001666//response to hypoxia;GO:0045814//negative regulation of gene expression, epigenetic;GO:0071455//cellular response to hyperoxia;GO:0042220//response to cocaine","K17399//DNA (cytosine-5)-methyltransferase 3B [EC:2.1.1.37]","XP_008965737.1//PREDICTED: DNA (cytosine-5)-methyltransferase 3B isoform X5 [Pan paniscus];XP_011526956.1//PREDICTED: DNA (cytosine-5)-methyltransferase 3B isoform X2 [Homo sapiens];NP_001193985.1//DNA (cytosine-5)-methyltransferase 3B isoform 8 [Homo sapiens];NP_787046.1//DNA (cytosine-5)-methyltransferase 3B isoform 6 [Homo sapiens];XP_008965732.1//PREDICTED: DNA (cytosine-5)-methyltransferase 3B isoform X1 [Pan paniscus]","1//3;3//A2MP1;2//1"]
[56605,5070,1.82,1,-0.863938450423971,0.000318534591940668,"*",{"v":8.06606e-05,"d":"8.07E-05"},"ERO1B","NA","NA","NA","K10976//ERO1-like protein beta [EC:1.8.4.-]","AAF97547.1//endoplasmic reticulum oxidoreductin 1-Lbeta [Homo sapiens]","3//A2MP1"]
[51136,2031,6.6,3.63,-0.862496476250065,{"v":1.52663367774295e-05,"d":"1.53E-05"},"*",{"v":3.04868E-6,"d":"3.05E-06"},"RNFT1","GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0046872//metal ion binding;GO:0016740//transferase activity","GO:0016567//protein ubiquitination","K10264//F-box and WD-40 domain protein 8;K11981//E3 ubiquitin-protein ligase NRDP1 [EC:2.3.2.27];K14555//U3 small nucleolar RNA-associated protein 13","NP_057209.3//RING finger and transmembrane domain-containing protein 1 [Homo sapiens]","3//A2MP1"]
[5108,8213,8.72,4.81,-0.858291241006884,{"v":5.81446845665962e-28,"d":"5.81E-28"},"*",{"v":1.7217e-29,"d":"1.72E-29"},"PCM1","GO:0016020//membrane;GO:0031965//nuclear membrane;GO:0035869//ciliary transition zone;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0034451//centriolar satellite;GO:0005814//centriole;GO:0036064//ciliary basal body;GO:0000242//pericentriolar material;GO:0043234//protein complex;GO:0005829//cytosol;GO:0045177//apical part of cell","GO:0042802//identical protein binding","GO:0007098//centrosome cycle;GO:0090316//positive regulation of intracellular protein transport;GO:0034453//microtubule anchoring;GO:0060271//cilium assembly;GO:0097711//ciliary basal body-plasma membrane docking;GO:0035735//intraciliary transport involved in cilium assembly;GO:0031122//cytoplasmic microtubule organization;GO:0050768//negative regulation of neurogenesis;GO:0035176//social behavior;GO:1905515//non-motile cilium assembly;GO:0034454//microtubule anchoring at centrosome;GO:0001764//neuron migration;GO:0010389//regulation of G2/M transition of mitotic cell cycle;GO:0071539//protein localization to centrosome;GO:0000086//G2/M transition of mitotic cell cycle;GO:0022027//interkinetic nuclear migration;GO:0097150//neuronal stem cell population maintenance","K16537//pericentriolar material 1 protein","NP_001339563.1//pericentriolar material 1 protein isoform 6 [Homo sapiens];NP_001339579.1//pericentriolar material 1 protein isoform 19 [Homo sapiens];NP_001339585.1//pericentriolar material 1 protein isoform 21 [Homo sapiens];NP_001339571.1//pericentriolar material 1 protein isoform 14 [Homo sapiens];NP_001339570.1//pericentriolar material 1 protein isoform 13 [Homo sapiens];NP_001339578.1//pericentriolar material 1 protein isoform 18 [Homo sapiens];NP_001339576.1//pericentriolar material 1 protein isoform 17 [Homo sapiens];NP_001339572.1//pericentriolar material 1 protein isoform 15 [Homo sapiens];NP_001339574.1//pericentriolar material 1 protein isoform 16 [Homo sapiens];NP_006188.3//pericentriolar material 1 protein isoform 1 [Homo sapiens];NP_001339569.1//pericentriolar material 1 protein isoform 12 [Homo sapiens];NP_001339586.1//pericentriolar material 1 protein isoform 22 [Homo sapiens];NP_001339562.1//pericentriolar material 1 protein isoform 5 [Homo sapiens];NP_001339565.1//pericentriolar material 1 protein isoform 8 [Homo sapiens];NP_001339566.1//pericentriolar material 1 protein isoform 9 [Homo sapiens];NP_001302436.1//pericentriolar material 1 protein isoform 2 [Homo sapiens];NP_001302437.1//pericentriolar material 1 protein isoform 3 [Homo sapiens];NP_001339564.1//pericentriolar material 1 protein isoform 7 [Homo sapiens];NP_001339568.1//pericentriolar material 1 protein isoform 11 [Homo sapiens];NP_001339561.1//pericentriolar material 1 protein isoform 4 [Homo sapiens];NP_001339567.1//pericentriolar material 1 protein isoform 10 [Homo sapiens]","1//3;3//A2MP1"]
[23271,7363,6.67,3.68,-0.857980995127572,{"v":2.07307513540946e-18,"d":"2.07E-18"},"*",{"v":1.125176e-19,"d":"1.13E-19"},"CAMSAP2","GO:1990752//microtubule end;GO:0005874//microtubule;GO:0005829//cytosol","GO:0005516//calmodulin binding;GO:0008017//microtubule binding;GO:0051011//microtubule minus-end binding;GO:0030507//spectrin binding","GO:0033043//regulation of organelle organization;GO:0000226//microtubule cytoskeleton organization;GO:0031175//neuron projection development","K17493//calmodulin-regulated spectrin-associated protein","NP_001284637.1//calmodulin-regulated spectrin-associated protein 2 isoform 3 [Homo sapiens];NP_001284636.1//calmodulin-regulated spectrin-associated protein 2 isoform 1 [Homo sapiens];NP_982284.1//calmodulin-regulated spectrin-associated protein 2 isoform 2 [Homo sapiens]","1//3;2//1"]
[57670,12427,3.56,1.97,-0.853681611510022,{"v":2.49232245607108e-16,"d":"2.49E-16"},"*",{"v":1.58052E-17,"d":"1.58E-17"},"KIAA1549","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","NA","NA","K10955//mucin-2;K22023//mucin-6","NP_001158137.1//UPF0606 protein KIAA1549 isoform 2 [Homo sapiens];NP_065961.2//UPF0606 protein KIAA1549 isoform 1 [Homo sapiens]","1//3;2//1"]
[4035,14905,3.23,1.79,-0.851574577429669,{"v":1.16709710163934e-17,"d":"1.17E-17"},"*",{"v":6.6852e-19,"d":"6.69E-19"},"LRP1","GO:0016020//membrane;GO:0030425//dendrite;GO:0016323//basolateral plasma membrane;GO:0030666//endocytic vesicle membrane;GO:0098797//plasma membrane protein complex;GO:0043235//receptor complex;GO:0043025//neuronal cell body;GO:0005730//nucleolus;GO:0005887//integral component of plasma membrane;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005769//early endosome;GO:0005765//lysosomal membrane;GO:0005925//focal adhesion;GO:0030136//clathrin-coated vesicle;GO:0005905//clathrin-coated pit","GO:0002020//protease binding;GO:0003723//RNA binding;GO:0070325//lipoprotein particle receptor binding;GO:0004872//receptor activity;GO:0034185//apolipoprotein binding;GO:0016964//alpha-2 macroglobulin receptor activity;GO:0030226//apolipoprotein receptor activity;GO:0032050//clathrin heavy chain binding;GO:0043395//heparan sulfate proteoglycan binding;GO:0005041//low-density lipoprotein receptor activity;GO:0005044//scavenger receptor activity;GO:0042954//lipoprotein transporter activity;GO:0005509//calcium ion binding;GO:0032403//protein complex binding","GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0031623//receptor internalization;GO:0032956//regulation of actin cytoskeleton organization;GO:0045807//positive regulation of endocytosis;GO:0032092//positive regulation of protein binding;GO:0021987//cerebral cortex development;GO:1903078//positive regulation of protein localization to plasma membrane;GO:0032429//regulation of phospholipase A2 activity;GO:0042157//lipoprotein metabolic process;GO:0006909//phagocytosis;GO:0010715//regulation of extracellular matrix disassembly;GO:0043524//negative regulation of neuron apoptotic process;GO:0043277//apoptotic cell clearance;GO:0001523//retinoid metabolic process;GO:0006898//receptor-mediated endocytosis;GO:0006629//lipid metabolic process;GO:0010875//positive regulation of cholesterol efflux;GO:0097242//amyloid-beta clearance;GO:0030178//negative regulation of Wnt signaling pathway;GO:0035909//aorta morphogenesis;GO:1900223//positive regulation of amyloid-beta clearance;GO:2000587//negative regulation of platelet-derived growth factor receptor-beta signaling pathway;GO:0008283//cell proliferation;GO:0010977//negative regulation of neuron projection development;GO:0042953//lipoprotein transport;GO:0032374//regulation of cholesterol transport;GO:0010942//positive regulation of cell death;GO:0002265//astrocyte activation involved in immune response;GO:0051246//regulation of protein metabolic process;GO:1904646//cellular response to amyloid-beta;GO:0007568//aging;GO:0032370//positive regulation of lipid transport;GO:0014912//negative regulation of smooth muscle cell migration;GO:0045732//positive regulation of protein catabolic process;GO:1905167//positive regulation of lysosomal protein catabolic process;GO:0051222//positive regulation of protein transport;GO:0045056//transcytosis","K04550//low-density lipoprotein receptor-related protein 1 (alpha-2-macroglobulin receptor)","NP_002323.2//prolow-density lipoprotein receptor-related protein 1 preproprotein [Homo sapiens]","2//1"]
[201562,4169,24.73,13.71,-0.851033668610712,{"v":1.34225338333333e-36,"d":"1.34E-36"},"*",{"v":2.82332e-38,"d":"2.82E-38"},"HACD2","GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0102158//very-long-chain 3-hydroxyacyl-CoA dehydratase activity;GO:0018812//3-hydroxyacyl-CoA dehydratase activity;GO:0102345//3-hydroxy-lignoceroyl-CoA dehydratase activity;GO:0019899//enzyme binding;GO:0102344//3-hydroxy-behenoyl-CoA dehydratase activity;GO:0102343//3-hydroxy-arachidoyl-CoA dehydratase activity","GO:0030497//fatty acid elongation;GO:0030148//sphingolipid biosynthetic process;GO:0006633//fatty acid biosynthetic process;GO:0042761//very long-chain fatty acid biosynthetic process","K10703//very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:4.2.1.134]","NP_001316713.1//very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 isoform a [Homo sapiens];NP_001316712.1//very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 isoform a [Homo sapiens];XP_011827005.1//PREDICTED: very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 [Mandrillus leucophaeus];XP_007983767.1//PREDICTED: very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase 2 isoform X1 [Chlorocebus sabaeus]","1//3;4"]
[1519,2943,1.08,0.6,-0.84799690655495,0.0537903431578947,"*",0.0230328,"CTSO","GO:0005615//extracellular space;GO:0005764//lysosome","GO:0008234//cysteine-type peptidase activity;GO:0004197//cysteine-type endopeptidase activity","GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0006508//proteolysis","K01374//cathepsin O [EC:3.4.22.42]","EAX04883.1//cathepsin O [Homo sapiens]","2//1"]
[10153,3341,18.49,10.28,-0.846904960210318,{"v":5.7658825465288E-22,"d":"5.77E-22"},"*",{"v":2.44366E-23,"d":"2.44E-23"},"CEBPZ","GO:0005634//nucleus","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003723//RNA binding;GO:0003677//DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter","K14832//ribosome biogenesis protein MAK21","NP_005751.2//CCAAT/enhancer-binding protein zeta [Homo sapiens]","2//1"]
[253430,6133,1.94,1.08,-0.845025340023659,{"v":5.49791917867272e-05,"d":"5.50E-05"},"*",{"v":1.213576e-05,"d":"1.21E-05"},"IPMK","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus","GO:0005524//ATP binding;GO:0000823//inositol-1,4,5-trisphosphate 6-kinase activity;GO:0000825//inositol tetrakisphosphate 6-kinase activity;GO:0008440//inositol-1,4,5-trisphosphate 3-kinase activity;GO:0047326//inositol tetrakisphosphate 5-kinase activity;GO:0000824//inositol tetrakisphosphate 3-kinase activity","GO:0043647//inositol phosphate metabolic process","K00915//inositol-polyphosphate multikinase [EC:2.7.1.140 2.7.1.151]","NP_689416.1//inositol polyphosphate multikinase [Homo sapiens]",4]
[158055,2587,0.77,0.43,-0.840521785992804,0.159309376189314,"*",0.081759,"C9orf163","NA","NA","NA","K16628//collagen, type VII, alpha;K10361//myosin XV","EAW88240.1//hypothetical protein FLJ36779, partial [Homo sapiens]","2//1"]
[5966,7842,1.52,0.85,-0.838536577305884,{"v":7.00426954738015e-05,"d":"7.00E-05"},"*",{"v":1.573264e-05,"d":"1.57E-05"},"REL","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription factor complex;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0033256//I-kappaB/NF-kappaB complex","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0003677//DNA binding;GO:0001205//transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0038061//NIK/NF-kappaB signaling;GO:1901215//negative regulation of neuron death;GO:0034097//response to cytokine;GO:0010629//negative regulation of gene expression;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006954//inflammatory response;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045087//innate immune response;GO:0032688//negative regulation of interferon-beta production","K09254//c-Rel proto-oncogene protein","NP_001278675.1//proto-oncogene c-Rel isoform 2 [Homo sapiens];NP_002899.1//proto-oncogene c-Rel isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[6319,5473,299.73,167.69,-0.83786683253167,0,"*",0,"SCD","GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0005730//nucleolus;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0005506//iron ion binding;GO:0004768//stearoyl-CoA 9-desaturase activity;GO:0016491//oxidoreductase activity","GO:0006636//unsaturated fatty acid biosynthetic process;GO:0046949//fatty-acyl-CoA biosynthetic process;GO:1903966//monounsaturated fatty acid biosynthetic process;GO:0045540//regulation of cholesterol biosynthetic process","K00507//stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]","BAD92219.1//stearoyl-CoA desaturase variant, partial [Homo sapiens]",4]
[7434,3793,0.66,0.37,-0.834940753729504,0.096893609521248,"*",0.0451046,"VIPR2","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004999//vasoactive intestinal polypeptide receptor activity;GO:0004930//G-protein coupled receptor activity","GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0007190//activation of adenylate cyclase activity;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0007166//cell surface receptor signaling pathway","K04590//vasoactive intestinal peptide receptor 2","NP_001291451.1//vasoactive intestinal polypeptide receptor 2 isoform 2 precursor [Homo sapiens];NP_003373.2//vasoactive intestinal polypeptide receptor 2 isoform 1 precursor [Homo sapiens];NP_001295188.1//vasoactive intestinal polypeptide receptor 2 isoform 3 [Homo sapiens]","4;1//3"]
[399967,1640,0.73,0.41,-0.832272554261934,0.348159208234689,"*",0.211742,"PATE2","GO:0005615//extracellular space","NA","NA","NA","NP_997720.1//prostate and testis expressed protein 2 precursor [Homo sapiens]","2//1"]
[23380,6306,9.52,5.35,-0.831422682019434,{"v":5.07172129970326e-22,"d":"5.07E-22"},"*",{"v":2.13994e-23,"d":"2.14E-23"},"SRGAP2","GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0030054//cell junction;GO:0014069//postsynaptic density;GO:0030027//lamellipodium;GO:0005737//cytoplasm;GO:0044327//dendritic spine head;GO:0045335//phagocytic vesicle;GO:0005829//cytosol;GO:0005743//mitochondrial inner membrane;GO:0005886//plasma membrane;GO:0045211//postsynaptic membrane","GO:0048365//Rac GTPase binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0005096//GTPase activator activity","GO:0034446//substrate adhesion-dependent cell spreading;GO:0007165//signal transduction;GO:0046847//filopodium assembly;GO:0060996//dendritic spine development;GO:0043547//positive regulation of GTPase activity;GO:2001223//negative regulation of neuron migration;GO:0048812//neuron projection morphogenesis;GO:0021816//extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration;GO:0003363//lamellipodium assembly involved in ameboidal cell migration;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0051014//actin filament severing","K07526//SLIT-ROBO Rho GTPase activating protein","NP_001164108.1//SLIT-ROBO Rho GTPase-activating protein 2 isoform c [Homo sapiens];NP_001287881.1//SLIT-ROBO Rho GTPase-activating protein 2 isoform d [Homo sapiens];NP_056141.2//SLIT-ROBO Rho GTPase-activating protein 2 isoform a [Homo sapiens]","1//3;4;3//A2MP1"]
[57337,4708,0.8,0.45,-0.830074998557688,0.0214159943093466,"*",0.0081044,"SENP7","GO:0005634//nucleus;GO:0005622//intracellular;GO:0005886//plasma membrane","GO:0008234//cysteine-type peptidase activity;GO:0004930//G-protein coupled receptor activity","GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway","K08596//sentrin-specific protease 7 [EC:3.4.22.68]","NP_065705.3//sentrin-specific protease 7 isoform 1 [Homo sapiens];XP_016862418.1//PREDICTED: sentrin-specific protease 7 isoform X12 [Homo sapiens];NP_001070671.1//sentrin-specific protease 7 isoform 2 [Homo sapiens];XP_005247719.1//PREDICTED: sentrin-specific protease 7 isoform X9 [Homo sapiens];NP_001269730.1//sentrin-specific protease 7 isoform 3 [Homo sapiens]","4;1//3;2//1"]
[5412,4355,3.62,2.04,-0.82742054511171,{"v":4.26727448803828e-06,"d":"4.27E-06"},"*",{"v":7.81648e-07,"d":"7.82E-07"},"UBL3","GO:0070062//extracellular exosome;GO:0005622//intracellular;GO:0005886//plasma membrane","NA","NA","K14802//phospholipid-transporting ATPase [EC:3.6.3.1]","XP_008515626.1//PREDICTED: ubiquitin-like protein 3 [Equus przewalskii]","3//A2MP1"]
[7840,12928,1.33,0.75,-0.826463745005309,{"v":1.19015220699926e-06,"d":"1.19E-06"},"*",{"v":2.00122E-7,"d":"2.00E-07"},"ALMS1","GO:0005929//cilium;GO:0000922//spindle pole;GO:0005829//cytosol;GO:0005813//centrosome","GO:0051393//alpha-actinin binding","GO:0016197//endosomal transport;GO:0010389//regulation of G2/M transition of mitotic cell cycle;GO:0097711//ciliary basal body-plasma membrane docking;GO:0000086//G2/M transition of mitotic cell cycle;GO:0051492//regulation of stress fiber assembly","K16741//alstrom syndrome protein 1","NP_055935.4//Alstrom syndrome protein 1 [Homo sapiens]",4]
[4303,3365,1.17,0.66,-0.825970600224951,0.0527776837072885,"*",0.0225298,"FOXO4","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0005737//cytoplasm","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0003677//DNA binding;GO:0042802//identical protein binding;GO:1990841//promoter-specific chromatin binding;GO:0043565//sequence-specific DNA binding;GO:0008134//transcription factor binding;GO:0019899//enzyme binding;GO:0003700//DNA binding transcription factor activity;GO:0008013//beta-catenin binding","GO:0007095//mitotic G2 DNA damage checkpoint;GO:0008286//insulin receptor signaling pathway;GO:0006355//regulation of transcription, DNA-templated;GO:1990785//response to water-immersion restraint stress;GO:0051151//negative regulation of smooth muscle cell differentiation;GO:0007050//cell cycle arrest;GO:0016579//protein deubiquitination;GO:0070317//negative regulation of G0 to G1 transition;GO:0014911//positive regulation of smooth muscle cell migration;GO:0008285//negative regulation of cell proliferation;GO:0016525//negative regulation of angiogenesis;GO:0006351//transcription, DNA-templated;GO:0007517//muscle organ development;GO:0006366//transcription from RNA polymerase II promoter;GO:0007568//aging;GO:0048863//stem cell differentiation;GO:0071158//positive regulation of cell cycle arrest;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0031667//response to nutrient levels","K12358//forkhead box protein O4","NP_001164402.1//forkhead box protein O4 isoform 2 [Homo sapiens];NP_005929.2//forkhead box protein O4 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[4038,8244,3.24,1.83,-0.824150164600582,{"v":1.04131728682171e-09,"d":"1.04E-09"},"*",{"v":1.1773e-10,"d":"1.18E-10"},"LRP4","GO:0030425//dendrite;GO:0031594//neuromuscular junction;GO:0014069//postsynaptic density;GO:0097060//synaptic membrane;GO:0043235//receptor complex;GO:0043025//neuronal cell body;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0016600//flotillin complex;GO:0005886//plasma membrane","GO:0097110//scaffold protein binding;GO:0005509//calcium ion binding;GO:0042813//Wnt-activated receptor activity;GO:0030971//receptor tyrosine kinase binding;GO:0034185//apolipoprotein binding;GO:0017147//Wnt-protein binding;GO:0042803//protein homodimerization activity","GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0001822//kidney development;GO:0044332//Wnt signaling pathway involved in dorsal/ventral axis specification;GO:0042733//embryonic digit morphogenesis;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0006897//endocytosis;GO:0051124//synaptic growth at neuromuscular junction;GO:0050808//synapse organization;GO:0071340//skeletal muscle acetylcholine-gated channel clustering;GO:0097105//presynaptic membrane assembly;GO:0097104//postsynaptic membrane assembly;GO:0030509//BMP signaling pathway;GO:0051290//protein heterotetramerization;GO:0048813//dendrite morphogenesis;GO:0042475//odontogenesis of dentin-containing tooth;GO:1901631//positive regulation of presynaptic membrane organization;GO:0060173//limb development;GO:0030279//negative regulation of ossification;GO:1904395//positive regulation of skeletal muscle acetylcholine-gated channel clustering;GO:0050771//negative regulation of axonogenesis;GO:0009954//proximal/distal pattern formation;GO:0001942//hair follicle development","K20051//low-density lipoprotein receptor-related protein 4","XP_019268022.1//PREDICTED: low-density lipoprotein receptor-related protein 4 [Panthera pardus]","3//A2MP1"]
[83478,4644,0.92,0.52,-0.823122237915921,0.0168903945584726,"*",0.00620252,"ARHGAP24","GO:0005856//cytoskeleton;GO:0042995//cell projection;GO:0005925//focal adhesion;GO:0005829//cytosol","GO:0005096//GTPase activator activity","GO:0007165//signal transduction;GO:0030154//cell differentiation;GO:0001525//angiogenesis;GO:0051056//regulation of small GTPase mediated signal transduction","K20642//Rho GTPase-activating protein 22/24/25","NP_112595.2//rho GTPase-activating protein 24 isoform 2 [Homo sapiens];NP_001274734.1//rho GTPase-activating protein 24 isoform 4 [Homo sapiens];NP_001333022.1//rho GTPase-activating protein 24 isoform 5 [Homo sapiens];XP_011807167.1//PREDICTED: rho GTPase-activating protein 24 isoform X2 [Colobus angolensis palliatus]","1//3;2//1"]
[22893,4615,6.09,3.45,-0.819845866240801,{"v":5.48388703788748e-10,"d":"5.48E-10"},"*",{"v":5.9803e-11,"d":"5.98E-11"},"BAHD1","GO:0005654//nucleoplasm;GO:0000785//chromatin;GO:0005677//chromatin silencing complex","GO:0003682//chromatin binding;GO:0000976//transcription regulatory region sequence-specific DNA binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0006342//chromatin silencing;GO:0016569//covalent chromatin modification;GO:0031507//heterochromatin assembly;GO:0006351//transcription, DNA-templated","K04533//huntingtin","XP_016783426.1//PREDICTED: bromo adjacent homology domain-containing 1 protein isoform X1 [Pan troglodytes];XP_016783427.1//PREDICTED: bromo adjacent homology domain-containing 1 protein isoform X2 [Pan troglodytes]","4;1//3"]
[94134,4964,9.21,5.22,-0.819151349521451,{"v":1.90700516363636e-15,"d":"1.91E-15"},"*",{"v":1.286936e-16,"d":"1.29E-16"},"ARHGAP12","GO:0005829//cytosol;GO:0001891//phagocytic cup","GO:0005096//GTPase activator activity","GO:0002011//morphogenesis of an epithelial sheet;GO:0006911//phagocytosis, engulfment;GO:0007015//actin filament organization;GO:0007165//signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0051058//negative regulation of small GTPase mediated signal transduction","K20636//Rho GTPase-activating protein 12/27","NP_001257627.1//rho GTPase-activating protein 12 isoform 5 [Homo sapiens];NP_001257625.1//rho GTPase-activating protein 12 isoform 3 [Homo sapiens];NP_001257628.1//rho GTPase-activating protein 12 isoform 6 [Homo sapiens];NP_001257626.1//rho GTPase-activating protein 12 isoform 4 [Homo sapiens];NP_001257624.1//rho GTPase-activating protein 12 isoform 2 [Homo sapiens];NP_060757.4//rho GTPase-activating protein 12 isoform 1 [Homo sapiens]","6;1//3"]
[135228,9170,11.74,6.67,-0.815673741925467,{"v":1.17798474865672E-36,"d":"1.18E-36"},"*",{"v":2.47042e-38,"d":"2.47E-38"},"CD109","GO:0005615//extracellular space;GO:0009986//cell surface;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0031225//anchored component of membrane;GO:0031092//platelet alpha granule membrane","GO:0004867//serine-type endopeptidase inhibitor activity;GO:0050431//transforming growth factor beta binding","GO:0010839//negative regulation of keratinocyte proliferation;GO:0006501//C-terminal protein lipidation;GO:0072675//osteoclast fusion;GO:0045616//regulation of keratinocyte differentiation;GO:0002576//platelet degranulation;GO:0001933//negative regulation of protein phosphorylation;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0061045//negative regulation of wound healing;GO:0001942//hair follicle development","K06530//CD109 antigen","XP_018884366.1//PREDICTED: CD109 antigen, partial [Gorilla gorilla gorilla];CAE46045.1//hypothetical protein, partial [Homo sapiens]","4;2//1"]
[6782,4001,5.15,2.93,-0.813671767648333,{"v":1.88239814687369e-07,"d":"1.88E-07"},"*",{"v":2.80816e-08,"d":"2.81E-08"},"HSPA13","GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0005783//endoplasmic reticulum","GO:0005524//ATP binding","NA","K09491//stress 70 protein chaperone microsome-associated 60kDa protein","NP_008879.3//heat shock 70 kDa protein 13 precursor [Homo sapiens]",4]
[9936,3821,2.23,1.27,-0.812215213148139,0.000842574092643052,"*",2.32296E-4,"CD302","GO:0016020//membrane;GO:0005887//integral component of plasma membrane;GO:0005938//cell cortex;GO:0016021//integral component of membrane;GO:0005902//microvillus;GO:0030175//filopodium","GO:0030246//carbohydrate binding;GO:0004888//transmembrane signaling receptor activity","GO:0006909//phagocytosis","K06722//CD302 antigen;K06559//lymphocyte antigen 75","NP_001185693.1//CD302 antigen isoform 3 precursor [Homo sapiens];NP_001185692.1//CD302 antigen isoform 2 precursor [Homo sapiens];NP_055695.2//CD302 antigen isoform 1 precursor [Homo sapiens]","1//3;4"]
[151195,3676,13.74,7.84,-0.809456444702892,{"v":7.90584098467824e-17,"d":"7.91E-17"},"*",{"v":4.84526e-18,"d":"4.85E-18"},"CCNYL1","GO:0005886//plasma membrane","GO:0019901//protein kinase binding","GO:0030317//flagellated sperm motility;GO:0007283//spermatogenesis;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity","K12491//Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1/3;K04613//vomeronasal 2 receptor;K18468//vacuolar protein sorting-associated protein 35","NP_001317147.1//cyclin-Y-like protein 1 isoform 3 [Homo sapiens];NP_001135772.1//cyclin-Y-like protein 1 isoform 1 [Homo sapiens];XP_018878136.1//PREDICTED: cyclin-Y-like protein 1 isoform X1 [Gorilla gorilla gorilla]","1//3;2//1"]
[161436,7171,0.21,0.12,-0.807354922057604,0.263840695443121,"*",0.151146,"EML5","NA","NA","NA","K18597//echinoderm microtubule-associated protein-like 5","XP_014701358.1//PREDICTED: echinoderm microtubule-associated protein-like 5 isoform X2 [Equus asinus]","2//1"]
[3800,6958,0.07,0.04,-0.807354922057604,0.499184970409918,"*",0.345342,"KIF5C","GO:0005874//microtubule;GO:0035253//ciliary rootlet;GO:0005737//cytoplasm;GO:0043005//neuron projection;GO:0005871//kinesin complex","GO:0005524//ATP binding;GO:0003777//microtubule motor activity;GO:0008017//microtubule binding;GO:0008574//ATP-dependent microtubule motor activity, plus-end-directed","GO:0007018//microtubule-based movement;GO:0008045//motor neuron axon guidance;GO:0008104//protein localization;GO:0006996//organelle organization;GO:0030705//cytoskeleton-dependent intracellular transport;GO:0007411//axon guidance;GO:0051028//mRNA transport","K10396//kinesin family member 5","NP_004513.1//kinesin heavy chain isoform 5C [Homo sapiens]","2//1"]
[2740,6698,0.07,0.04,-0.807354922057604,0.49855337623136,"*",0.345342,"GLP1R","GO:0005887//integral component of plasma membrane;GO:0005622//intracellular;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004967//glucagon receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0044508//glucagon-like peptide 1 receptor activity","GO:0045777//positive regulation of blood pressure;GO:0006950//response to stress;GO:0007166//cell surface receptor signaling pathway;GO:0050796//regulation of insulin secretion;GO:0019933//cAMP-mediated signaling;GO:0007190//activation of adenylate cyclase activity;GO:0008016//regulation of heart contraction;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007611//learning or memory","K04581//glucagon-like peptide 1 receptor","NP_002053.3//glucagon-like peptide 1 receptor precursor [Homo sapiens]",4]
[83540,1900,14.36,8.21,-0.806601622045247,{"v":6.99009236856981e-10,"d":"6.99E-10"},"*",{"v":7.741e-11,"d":"7.74E-11"},"NUF2","GO:0016020//membrane;GO:0005634//nucleus;GO:0005829//cytosol;GO:0000777//condensed chromosome kinetochore;GO:0031262//Ndc80 complex;GO:0000775//chromosome, centromeric region","NA","GO:0000278//mitotic cell cycle;GO:0007059//chromosome segregation;GO:0007062//sister chromatid cohesion;GO:0051301//cell division","K11548//kinetochore protein Nuf2","NP_113611.2//kinetochore protein Nuf2 [Homo sapiens]","3//A2MP1;2//1"]
[1870,5201,6.31,3.61,-0.805641168095378,{"v":3.82075888073395e-11,"d":"3.82E-11"},"*",{"v":3.64998e-12,"d":"3.65E-12"},"E2F2","GO:0090575//RNA polymerase II transcription factor complex;GO:0005654//nucleoplasm","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0008134//transcription factor binding;GO:0003700//DNA binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0001047//core promoter binding","GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0051726//regulation of cell cycle;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:1990086//lens fiber cell apoptotic process;GO:0007049//cell cycle","K09389//transcription factor E2F2","NP_004082.1//transcription factor E2F2 [Homo sapiens]","3//A2MP1"]
[5287,7606,5.22,2.99,-0.803904322371779,{"v":3.19762261454261e-13,"d":"3.20E-13"},"*",{"v":2.56026e-14,"d":"2.56E-14"},"PIK3C2B","GO:0005654//nucleoplasm;GO:0005783//endoplasmic reticulum;GO:0030139//endocytic vesicle;GO:0005942//phosphatidylinositol 3-kinase complex;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0001727//lipid kinase activity;GO:0005524//ATP binding;GO:0016303//1-phosphatidylinositol-3-kinase activity;GO:0016301//kinase activity;GO:0035005//1-phosphatidylinositol-4-phosphate 3-kinase activity;GO:0035091//phosphatidylinositol binding","GO:0016477//cell migration;GO:1905037//autophagosome organization;GO:0009267//cellular response to starvation;GO:0036092//phosphatidylinositol-3-phosphate biosynthetic process;GO:0043491//protein kinase B signaling;GO:0006661//phosphatidylinositol biosynthetic process;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0046854//phosphatidylinositol phosphorylation;GO:0048015//phosphatidylinositol-mediated signaling","K00923//phosphatidylinositol-4-phosphate 3-kinase [EC:2.7.1.154]","NP_002637.3//phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta [Homo sapiens]","3//A2MP1"]
[2187,2994,1.9,1.09,-0.801671283554021,0.0104254670774775,"*",0.00362222,"FANCB","GO:0005654//nucleoplasm;GO:0043240//Fanconi anaemia nuclear complex","NA","GO:0036297//interstrand cross-link repair","K10889//fanconi anemia group B protein","NP_689846.1//Fanconi anemia group B protein [Homo sapiens]","1//3;3//A2MP1;2//1"]
[57669,6052,1.95,1.12,-0.799975391692006,0.000148650389926548,"*",{"v":3.54736e-05,"d":"3.55E-05"},"EPB41L5","GO:0005856//cytoskeleton;GO:0005925//focal adhesion;GO:0005829//cytosol;GO:0032587//ruffle membrane;GO:0005912//adherens junction;GO:0005886//plasma membrane","GO:0019904//protein domain specific binding;GO:0008092//cytoskeletal protein binding;GO:0005200//structural constituent of cytoskeleton","GO:0048617//embryonic foregut morphogenesis;GO:0031032//actomyosin structure organization;GO:0032525//somite rostral/caudal axis specification;GO:0010608//posttranscriptional regulation of gene expression;GO:0032092//positive regulation of protein binding;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0022408//negative regulation of cell-cell adhesion;GO:0010634//positive regulation of epithelial cell migration;GO:0070986//left/right axis specification;GO:0032091//negative regulation of protein binding;GO:0007509//mesoderm migration involved in gastrulation;GO:0001837//epithelial to mesenchymal transition;GO:0070201//regulation of establishment of protein localization;GO:0048339//paraxial mesoderm development;GO:0007492//endoderm development;GO:0009826//unidimensional cell growth;GO:0051894//positive regulation of focal adhesion assembly;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0001701//in utero embryonic development;GO:0007398//ectoderm development;GO:0006931//substrate-dependent cell migration, cell attachment to substrate;GO:0048319//axial mesoderm morphogenesis;GO:0003383//apical constriction;GO:0001839//neural plate morphogenesis","K21111//band 4.1-like protein 4B","NP_001317239.1//band 4.1-like protein 5 isoform 5 [Homo sapiens];NP_065960.2//band 4.1-like protein 5 isoform 1 [Homo sapiens];NP_001171866.1//band 4.1-like protein 5 isoform 2 [Homo sapiens];XP_016805099.1//PREDICTED: band 4.1-like protein 5 isoform X12 [Pan troglodytes];NP_001171867.1//band 4.1-like protein 5 isoform 3 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[4811,5903,3.6,2.07,-0.79836613883035,{"v":1.98928120217664e-07,"d":"1.99E-07"},"*",{"v":2.97508e-08,"d":"2.98E-08"},"NID1","GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0005605//basal lamina;GO:0005576//extracellular region;GO:0071944//cell periphery;GO:0005604//basement membrane","GO:0043237//laminin-1 binding;GO:0005518//collagen binding;GO:0005509//calcium ion binding;GO:0043236//laminin binding;GO:0043394//proteoglycan binding","GO:0022617//extracellular matrix disassembly;GO:0007160//cell-matrix adhesion;GO:0071711//basement membrane organization;GO:0032836//glomerular basement membrane development;GO:0030198//extracellular matrix organization;GO:0010811//positive regulation of cell-substrate adhesion","K06826//nidogen (entactin)","NP_002499.2//nidogen-1 precursor [Homo sapiens]","2//1"]
[8661,6726,28.22,16.25,-0.796278269794085,{"v":5.84917053636364e-60,"d":"5.85E-60"},"*",{"v":6.44456e-62,"d":"6.44E-62"},"EIF3A","GO:0016020//membrane;GO:0005634//nucleus;GO:0005874//microtubule;GO:0005737//cytoplasm;GO:0016282//eukaryotic 43S preinitiation complex;GO:0071541//eukaryotic translation initiation factor 3 complex, eIF3m;GO:0043614//multi-eIF complex;GO:0005730//nucleolus;GO:0071540//eukaryotic translation initiation factor 3 complex, eIF3e;GO:0005829//cytosol;GO:0033290//eukaryotic 48S preinitiation complex;GO:0005852//eukaryotic translation initiation factor 3 complex","GO:0003743//translation initiation factor activity;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0030971//receptor tyrosine kinase binding;GO:0005198//structural molecule activity","GO:0075522//IRES-dependent viral translational initiation;GO:0075525//viral translational termination-reinitiation;GO:0001731//formation of translation preinitiation complex;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0006413//translational initiation;GO:0006446//regulation of translational initiation;GO:0001732//formation of cytoplasmic translation initiation complex;GO:0002188//translation reinitiation","K03254//translation initiation factor 3 subunit A","NP_003741.1//eukaryotic translation initiation factor 3 subunit A [Homo sapiens]","3//A2MP1"]
[9444,9826,7.27,4.19,-0.795005120220243,{"v":1.56867152755418e-22,"d":"1.57E-22"},"*",{"v":6.34382e-24,"d":"6.34E-24"},"QKI","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0003729//mRNA binding;GO:0003723//RNA binding;GO:0017124//SH3 domain binding","GO:0042552//myelination;GO:0006397//mRNA processing;GO:0030154//cell differentiation;GO:0042759//long-chain fatty acid biosynthetic process;GO:0007286//spermatid development;GO:0010628//positive regulation of gene expression;GO:0006417//regulation of translation;GO:0008366//axon ensheathment;GO:0051028//mRNA transport;GO:0061158//3'-UTR-mediated mRNA destabilization;GO:0042692//muscle cell differentiation;GO:0007275//multicellular organism development;GO:0008380//RNA splicing;GO:0001570//vasculogenesis","K14945//protein quaking","AAF63414.1//QUAKING isoform 6 [Homo sapiens];AAF63413.1//QUAKING isoform 2 [Homo sapiens];AAF63417.1//QUAKING isoform 3 [Homo sapiens];NP_996737.1//protein quaking isoform 4 [Homo sapiens]","1//3;2//1"]
[26149,4135,1.3,0.75,-0.793549122532574,0.0104799679006122,"*",0.00364378,"ZNF658","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0042254//ribosome biogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0071294//cellular response to zinc ion;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","NP_149350.3//zinc finger protein 658 [Homo sapiens]","6;1//3"]
[54905,2354,0.64,0.37,-0.79054663437105,0.244129689813167,"*",0.1374242,"CYP2W1","GO:0005788//endoplasmic reticulum lumen;GO:0009986//cell surface;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane","GO:0008395//steroid hydroxylase activity;GO:0020037//heme binding;GO:0005506//iron ion binding;GO:0004497//monooxygenase activity;GO:0008392//arachidonic acid epoxygenase activity","GO:0006805//xenobiotic metabolic process;GO:0043390//aflatoxin B1 metabolic process;GO:0019373//epoxygenase P450 pathway","K07423//cytochrome P450 family 2 subfamily W polypeptide 1","NP_060251.2//cytochrome P450 2W1 precursor [Homo sapiens]","2//1"]
[57551,11779,8.03,4.65,-0.788169271521921,{"v":4.62654501552106e-29,"d":"4.63E-29"},"*",{"v":1.30623E-30,"d":"1.31E-30"},"TAOK1","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0004709//MAP kinase kinase kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0016301//kinase activity;GO:0016740//transferase activity","GO:0046330//positive regulation of JNK cascade;GO:0007399//nervous system development;GO:0007346//regulation of mitotic cell cycle;GO:0006281//DNA repair;GO:0006468//protein phosphorylation;GO:0032874//positive regulation of stress-activated MAPK cascade;GO:0097194//execution phase of apoptosis;GO:0007062//sister chromatid cohesion;GO:0051493//regulation of cytoskeleton organization;GO:0031098//stress-activated protein kinase signaling cascade;GO:0006974//cellular response to DNA damage stimulus;GO:0031572//G2 DNA damage checkpoint;GO:0042981//regulation of apoptotic process","K04429//thousand and one amino acid protein kinase [EC:2.7.11.1]","NP_065842.1//serine/threonine-protein kinase TAO1 isoform 1 [Homo sapiens];NP_079418.1//serine/threonine-protein kinase TAO1 isoform 2 [Homo sapiens]","1//3;2//1"]
[10194,4897,3,1.74,-0.785875194647153,{"v":1.75143570737756e-05,"d":"1.75E-05"},"*",{"v":3.53708e-06,"d":"3.54E-06"},"TSHZ1","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0009952//anterior/posterior pattern specification;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0042474//middle ear morphogenesis;GO:0007275//multicellular organism development;GO:0006351//transcription, DNA-templated;GO:0060023//soft palate development","K09236//teashirt","XP_001137580.2//PREDICTED: teashirt homolog 1 isoform X1 [Pan troglodytes];NP_001295139.1//teashirt homolog 1 isoform 1 [Homo sapiens]","1//3;5"]
[23089,6628,27.57,16,-0.785027362235466,{"v":2.04256443560209e-56,"d":"2.04E-56"},"*",{"v":2.44228E-58,"d":"2.44E-58"},"PEG10","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0003676//nucleic acid binding","GO:0030154//cell differentiation;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0001890//placenta development;GO:0006915//apoptotic process","K05748//WAS protein family, member 2","XP_021545272.1//retrotransposon-derived protein PEG10 isoform X1 [Neomonachus schauinslandi]","1//3;3//A2MP1;2//1"]
[4437,4472,6.2,3.6,-0.784271308944563,{"v":4.07455664e-09,"d":"4.07E-09"},"*",{"v":4.91018e-10,"d":"4.91E-10"},"MSH3","GO:0016020//membrane;GO:0005654//nucleoplasm;GO:0032302//MutSbeta complex","GO:0000406//double-strand/single-strand DNA junction binding;GO:0003684//damaged DNA binding;GO:0005524//ATP binding;GO:0000404//heteroduplex DNA loop binding;GO:0000403//Y-form DNA binding;GO:0008094//DNA-dependent ATPase activity;GO:0019899//enzyme binding","GO:0045910//negative regulation of DNA recombination;GO:0006281//DNA repair;GO:0006298//mismatch repair;GO:0016447//somatic recombination of immunoglobulin gene segments;GO:0043570//maintenance of DNA repeat elements;GO:0051096//positive regulation of helicase activity","K08736//DNA mismatch repair protein MSH3","NP_002430.3//DNA mismatch repair protein Msh3 [Homo sapiens]",4]
[83543,3440,1.41,0.82,-0.78199934778071,0.0216149606677686,"*",0.00818646,"AIF1L","GO:0005856//cytoskeleton;GO:0070062//extracellular exosome;GO:0005925//focal adhesion;GO:0032587//ruffle membrane;GO:0005737//cytoplasm;GO:0005884//actin filament;GO:0043234//protein complex;GO:0015629//actin cytoskeleton","GO:0051015//actin filament binding;GO:0005509//calcium ion binding","NA","K18617//allograft inflammatory factor 1","NP_001172024.1//allograft inflammatory factor 1-like isoform 3 [Homo sapiens];NP_001172025.1//allograft inflammatory factor 1-like isoform 4 [Homo sapiens];NP_113614.1//allograft inflammatory factor 1-like isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[22828,5112,7.66,4.46,-0.780300682004652,{"v":1.90294300448e-13,"d":"1.90E-13"},"*",{"v":1.489094e-14,"d":"1.49E-14"},"SCAF8","GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0016363//nuclear matrix","GO:0043175//RNA polymerase core enzyme binding;GO:0003723//RNA binding","GO:0006397//mRNA processing;GO:0008380//RNA splicing","K13191//RNA-binding protein 16;K16847//T-lymphoma invasion and metastasis-inducing protein 2","XP_008005850.1//PREDICTED: protein SCAF8 isoform X4 [Chlorocebus sabaeus];NP_001273117.1//protein SCAF8 isoform a [Homo sapiens]","1//3;4"]
[23181,6014,4.36,2.54,-0.779499638004761,{"v":1.4373614695082E-9,"d":"1.44E-09"},"*",{"v":1.646658e-10,"d":"1.65E-10"},"DIP2A","NA","GO:0003824//catalytic activity","GO:0008152//metabolic process","K05637//laminin, alpha 1/2;K09291//nucleoprotein TPR","XP_020140384.1//disco-interacting protein 2 homolog A isoform X4 [Microcebus murinus];EAX09272.1//DIP2 disco-interacting protein 2 homolog A (Drosophila), isoform CRA_b, partial [Homo sapiens];XP_008062757.1//disco-interacting protein 2 homolog A isoform X2 [Carlito syrichta];XP_012969374.1//disco-interacting protein 2 homolog A isoform X5 [Mesocricetus auratus];XP_008062756.1//disco-interacting protein 2 homolog A isoform X1 [Carlito syrichta];XP_004416258.1//PREDICTED: disco-interacting protein 2 homolog A isoform X3 [Odobenus rosmarus divergens]","1//3;3//A2MP1;2//1"]
[54331,3899,1.44,0.84,-0.777607578663552,0.0165784747122118,"*",0.00607656,"GNG2","NA","NA","NA","K07826//guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2","XP_010630857.1//PREDICTED: guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 isoform X1 [Fukomys damarensis];EAW65665.1//guanine nucleotide binding protein (G protein), gamma 2, isoform CRA_c [Homo sapiens]","1//3;4"]
[221035,5205,11.81,6.91,-0.773251349008899,{"v":7.5784099497006e-19,"d":"7.58E-19"},"*",{"v":3.96142e-20,"d":"3.96E-20"},"REEP3","GO:0005874//microtubule;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","NA","GO:0007084//mitotic nuclear envelope reassembly;GO:0051301//cell division;GO:0006998//nuclear envelope organization","K17338//receptor expression-enhancing protein 1/2/3/4","NP_001001330.1//receptor expression-enhancing protein 3 [Homo sapiens]","2//1"]
[55669,3527,6.49,3.8,-0.772219059668191,{"v":1.70644342664418e-07,"d":"1.71E-07"},"*",{"v":2.53392E-8,"d":"2.53E-08"},"MFN1","GO:0016021//integral component of membrane;GO:0005741//mitochondrial outer membrane","GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0008053//mitochondrial fusion","K21356//mitofusin 1 [EC:3.6.5.-]","XP_017361786.1//PREDICTED: mitofusin-1 isoform X1 [Cebus capucinus imitator]","2//1"]
[3652,3207,1.81,1.06,-0.771925432520006,0.00887716001467621,"*",0.00302926,"IPP","GO:0015629//actin cytoskeleton;GO:0005737//cytoplasm;GO:0031463//Cul3-RING ubiquitin ligase complex","GO:0003779//actin binding","GO:0016567//protein ubiquitination","K13956//actin-binding protein IPP","NP_001138821.1//actin-binding protein IPP isoform 2 [Homo sapiens];NP_005888.1//actin-binding protein IPP isoform 1 [Homo sapiens]","1//3;2//1"]
[5775,11381,1.55,0.91,-0.768329765075541,{"v":5.74851155942417e-06,"d":"5.75E-06"},"*",{"v":1.074922E-6,"d":"1.07E-06"},"PTPN4","GO:0005856//cytoskeleton;GO:0009898//cytoplasmic side of plasma membrane;GO:0005737//cytoplasm","GO:0004726//non-membrane spanning protein tyrosine phosphatase activity;GO:0008092//cytoskeletal protein binding","GO:0006470//protein dephosphorylation","K18037//tyrosine-protein phosphatase non-receptor type 4 [EC:3.1.3.48]","XP_005572994.2//PREDICTED: tyrosine-protein phosphatase non-receptor type 4 isoform X2 [Macaca fascicularis]","3//A2MP1"]
[9873,4507,4.36,2.56,-0.768184324776927,{"v":1.5983599618908e-06,"d":"1.60E-06"},"*",{"v":2.73064e-07,"d":"2.73E-07"},"FCHSD2","GO:0031594//neuromuscular junction;GO:0055037//recycling endosome","NA","GO:0030833//regulation of actin filament polymerization;GO:0007274//neuromuscular synaptic transmission","K20125//F-BAR and double SH3 domains protein","NP_055639.2//F-BAR and double SH3 domains protein 2 [Homo sapiens]","2//1"]
[25903,3796,0.17,0.1,-0.765534746362977,0.582828036992636,"*",0.426084,"OLFML2B","GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix","GO:0050840//extracellular matrix binding","GO:0030198//extracellular matrix organization","K04592//latrophilin 1","NP_001284642.1//olfactomedin-like protein 2B isoform 1 precursor [Homo sapiens];NP_056256.1//olfactomedin-like protein 2B isoform 2 precursor [Homo sapiens];NP_001334629.1//olfactomedin-like protein 2B isoform 3 precursor [Homo sapiens]","1//3;2//1"]
[134637,7147,1.58,0.93,-0.764621937069072,0.000620359595423768,"*",0.0001663328,"ADAT2","NA","GO:0008270//zinc ion binding;GO:0008251//tRNA-specific adenosine deaminase activity","GO:0002100//tRNA wobble adenosine to inosine editing","K15441//tRNA-specific adenosine deaminase 2 [EC:3.5.4.-]","XP_001924271.1//tRNA-specific adenosine deaminase 2 [Sus scrofa];XP_008577084.1//PREDICTED: tRNA-specific adenosine deaminase 2 [Galeopterus variegatus]","1//3;2//1"]
[26115,11747,4.74,2.79,-0.764621937069072,{"v":6.01865551129363E-17,"d":"6.02E-17"},"*",{"v":3.66982e-18,"d":"3.67E-18"},"TANC2","NA","NA","GO:0001701//in utero embryonic development","K21440//ankyrin repeat domain-containing protein 50","NP_079461.2//protein TANC2 [Homo sapiens]","3//A2MP1"]
[65986,9242,1.12,0.66,-0.762960802699151,0.00115558563624309,"*",0.000327346,"ZBTB10","GO:0005654//nucleoplasm","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K10497//zinc finger and BTB domain-containing protein 10","NP_001099009.1//zinc finger and BTB domain-containing protein 10 isoform a [Homo sapiens];NP_076418.3//zinc finger and BTB domain-containing protein 10 isoform b [Homo sapiens];XP_021521595.1//LOW QUALITY PROTEIN: zinc finger and BTB domain-containing protein 10 [Aotus nancymaae]","1//3;4;2//1"]
[7011,10554,2.15,1.27,-0.759508162817294,{"v":6.86320369964664e-08,"d":"6.86E-08"},"*",{"v":9.72724e-09,"d":"9.73E-09"},"TEP1","GO:0000781//chromosome, telomeric region;GO:0016363//nuclear matrix;GO:0005737//cytoplasm;GO:0071013//catalytic step 2 spliceosome;GO:0030529//intracellular ribonucleoprotein complex;GO:0005697//telomerase holoenzyme complex;GO:0005682//U5 snRNP;GO:0071011//precatalytic spliceosome","GO:0003723//RNA binding;GO:0005524//ATP binding;GO:0002039//p53 binding;GO:0003720//telomerase activity;GO:0019899//enzyme binding;GO:0070034//telomerase RNA binding","GO:0000722//telomere maintenance via recombination;GO:0008380//RNA splicing","K11127//telomerase protein component 1","NP_009041.2//telomerase protein component 1 isoform 1 [Homo sapiens];NP_001305964.1//telomerase protein component 1 isoform 2 [Homo sapiens]","4;1//3"]
[7248,8572,4.13,2.44,-0.759260633856559,{"v":5.09749459459459e-11,"d":"5.10E-11"},"*",{"v":4.959e-12,"d":"4.96E-12"},"TSC1","GO:0016020//membrane;GO:0005856//cytoskeleton;GO:0033596//TSC1-TSC2 complex;GO:0005634//nucleus;GO:0005938//cell cortex;GO:0030027//lamellipodium;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0005884//actin filament;GO:0030426//growth cone;GO:0043234//protein complex;GO:0005829//cytosol;GO:0005811//lipid droplet;GO:0005886//plasma membrane","GO:0047485//protein N-terminus binding;GO:0051087//chaperone binding;GO:0032794//GTPase activating protein binding","GO:0045859//regulation of protein kinase activity;GO:0001952//regulation of cell-matrix adhesion;GO:0043666//regulation of phosphoprotein phosphatase activity;GO:0021766//hippocampus development;GO:0008344//adult locomotory behavior;GO:0032956//regulation of actin cytoskeleton organization;GO:0051893//regulation of focal adhesion assembly;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0017148//negative regulation of translation;GO:0021987//cerebral cortex development;GO:0008285//negative regulation of cell proliferation;GO:0006813//potassium ion transport;GO:0090630//activation of GTPase activity;GO:0055007//cardiac muscle cell differentiation;GO:0090650//cellular response to oxygen-glucose deprivation;GO:1903204//negative regulation of oxidative stress-induced neuron death;GO:0051894//positive regulation of focal adhesion assembly;GO:0002250//adaptive immune response;GO:0045792//negative regulation of cell size;GO:0007160//cell-matrix adhesion;GO:0046323//glucose import;GO:0051726//regulation of cell cycle;GO:0001843//neural tube closure;GO:0034260//negative regulation of GTPase activity;GO:1901214//regulation of neuron death;GO:0032007//negative regulation of TOR signaling;GO:0001822//kidney development;GO:0007050//cell cycle arrest;GO:0010977//negative regulation of neuron projection development;GO:0050808//synapse organization;GO:0051492//regulation of stress fiber assembly;GO:0043379//memory T cell differentiation;GO:0042552//myelination;GO:0051291//protein heterooligomerization;GO:0006407//rRNA export from nucleus;GO:0032868//response to insulin;GO:0030030//cell projection organization;GO:0006417//regulation of translation;GO:0061024//membrane organization;GO:0043087//regulation of GTPase activity;GO:0016239//positive regulation of macroautophagy;GO:0051496//positive regulation of stress fiber assembly;GO:0050821//protein stabilization;GO:0016242//negative regulation of macroautophagy","K07206//tuberous sclerosis 1","NP_001155899.1//hamartin isoform 4 [Homo sapiens];NP_001155898.1//hamartin isoform 3 [Homo sapiens];NP_000359.1//hamartin isoform 1 [Homo sapiens]","4;1//3"]
[79955,2870,1.3,0.77,-0.755581272333553,0.205705096658517,"*",0.1106048,"PDZD7","GO:0005929//cilium;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0002141//stereocilia ankle link;GO:1990696//USH2 complex","GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity","GO:0045184//establishment of protein localization;GO:0060088//auditory receptor cell stereocilium organization;GO:0050910//detection of mechanical stimulus involved in sensory perception of sound","K21882//PDZ domain-containing protein 7","NP_079171.1//PDZ domain-containing protein 7 isoform 2 [Homo sapiens];NP_001182192.1//PDZ domain-containing protein 7 isoform 1 [Homo sapiens];NP_001337973.1//PDZ domain-containing protein 7 isoform 3 [Homo sapiens]","1//3;4"]
[54578,1871,3.93,2.33,-0.754199357604326,0.0096021327388535,"*",0.0033031,"UGT1A6","GO:0070062//extracellular exosome;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0046982//protein heterodimerization activity;GO:0015020//glucuronosyltransferase activity;GO:0042803//protein homodimerization activity;GO:0019899//enzyme binding","GO:2001030//negative regulation of cellular glucuronidation;GO:0008152//metabolic process;GO:0052697//xenobiotic glucuronidation;GO:0006805//xenobiotic metabolic process;GO:0052695//cellular glucuronidation;GO:0045922//negative regulation of fatty acid metabolic process;GO:1904224//negative regulation of glucuronosyltransferase activity;GO:0052696//flavonoid glucuronidation","K00699//glucuronosyltransferase [EC:2.4.1.17]","NP_001063.2//UDP-glucuronosyltransferase 1-6 isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[114335,732,0.64,0.38,-0.752072486556414,0.631085667338397,"*",0.50972,"CGB1","GO:0005576//extracellular region","GO:0005179//hormone activity","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0016486//peptide hormone processing;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0007292//female gamete generation;GO:0006915//apoptotic process","K10045//chorionic gonadotropin, beta polypeptide","EAW52435.1//chorionic gonadotropin, beta polypeptide 2 [Homo sapiens]","1//3"]
[348093,2023,14.96,8.89,-0.750854851057867,{"v":3.52374916675379e-09,"d":"3.52E-09"},"*",{"v":4.21994e-10,"d":"4.22E-10"},"RBPMS2","GO:0005737//cytoplasm","GO:0003729//mRNA binding;GO:0042803//protein homodimerization activity","GO:0030514//negative regulation of BMP signaling pathway;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0051151//negative regulation of smooth muscle cell differentiation;GO:0048557//embryonic digestive tract morphogenesis","K02728//20S proteasome subunit alpha 3 [EC:3.4.25.1];K21245//transcription factor SPT20 homolog","NP_919248.1//RNA-binding protein with multiple splicing 2 [Homo sapiens]","2//1"]
[6873,5049,7.8,4.64,-0.749349318622039,{"v":8.00547863414634e-12,"d":"8.01E-12"},"*",{"v":7.1916e-13,"d":"7.19E-13"},"TAF2","GO:0033276//transcription factor TFTC complex;GO:0005654//nucleoplasm;GO:0005669//transcription factor TFIID complex","GO:0003682//chromatin binding;GO:0043565//sequence-specific DNA binding;GO:0001129//RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly;GO:0044212//transcription regulatory region DNA binding","GO:0006368//transcription elongation from RNA polymerase II promoter;GO:1901796//regulation of signal transduction by p53 class mediator;GO:0014070//response to organic cyclic compound;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0000086//G2/M transition of mitotic cell cycle;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter","K03128//transcription initiation factor TFIID subunit 2","NP_003175.1//transcription initiation factor TFIID subunit 2 [Homo sapiens]","3//A2MP1"]
[7508,3654,12.08,7.19,-0.748556778885781,{"v":2.05057615306285E-13,"d":"2.05E-13"},"*",{"v":1.613606e-14,"d":"1.61E-14"},"XPC","GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000111//nucleotide-excision repair factor 2 complex;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0071942//XPC complex","GO:0003697//single-stranded DNA binding;GO:0000405//bubble DNA binding;GO:0003684//damaged DNA binding;GO:0000404//heteroduplex DNA loop binding","GO:0042493//response to drug;GO:0010996//response to auditory stimulus;GO:0000715//nucleotide-excision repair, DNA damage recognition;GO:0006281//DNA repair;GO:0006298//mismatch repair;GO:0000717//nucleotide-excision repair, DNA duplex unwinding;GO:0010224//response to UV-B;GO:0070911//global genome nucleotide-excision repair;GO:0006289//nucleotide-excision repair;GO:0006294//nucleotide-excision repair, preincision complex assembly;GO:1901990//regulation of mitotic cell cycle phase transition;GO:0031573//intra-S DNA damage checkpoint;GO:0070914//UV-damage excision repair","K10838//xeroderma pigmentosum group C-complementing protein","NP_001341658.1//DNA repair protein complementing XP-C cells isoform 5 [Homo sapiens];NP_001341659.1//DNA repair protein complementing XP-C cells isoform 6 [Homo sapiens];NP_004619.3//DNA repair protein complementing XP-C cells [Homo sapiens];NP_001341656.1//DNA repair protein complementing XP-C cells isoform 4 [Homo sapiens]","4;1//3"]
[10743,7668,21.56,12.85,-0.746588818671265,{"v":7.14302765555555e-47,"d":"7.14E-47"},"*",{"v":1.126858e-48,"d":"1.13E-48"},"RAI1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion","GO:0046872//metal ion binding;GO:0035326//enhancer binding;GO:0044212//transcription regulatory region DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0040015//negative regulation of multicellular organism growth;GO:0032922//circadian regulation of gene expression;GO:0001501//skeletal system development;GO:0045893//positive regulation of transcription, DNA-templated","K19749//retinoic acid-induced protein 1","NP_109590.3//retinoic acid-induced protein 1 [Homo sapiens]","3//A2MP1"]
[9282,6768,13.04,7.78,-0.745101809244885,{"v":3.57257638690909e-25,"d":"3.57E-25"},"*",{"v":1.230072E-26,"d":"1.23E-26"},"MED14","GO:0016020//membrane;GO:0070847//core mediator complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016592//mediator complex","GO:0042809//vitamin D receptor binding;GO:0003713//transcription coactivator activity;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0004872//receptor activity;GO:0003712//transcription cofactor activity;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0019827//stem cell population maintenance;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0030521//androgen receptor signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated","K15156//mediator of RNA polymerase II transcription subunit 14","NP_004220.2//mediator of RNA polymerase II transcription subunit 14 [Homo sapiens]","3//A2MP1"]
[158880,4410,0.72,0.43,-0.743660246740214,0.100979890159325,"*",0.0472154,"USP51","GO:0005694//chromosome","GO:0042393//histone binding;GO:0004843//thiol-dependent ubiquitin-specific protease activity;GO:0003682//chromatin binding;GO:0008270//zinc ion binding","GO:0016578//histone deubiquitination;GO:0006281//DNA repair;GO:2001032//regulation of double-strand break repair via nonhomologous end joining;GO:2001020//regulation of response to DNA damage stimulus;GO:0010569//regulation of double-strand break repair via homologous recombination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination;GO:0010564//regulation of cell cycle process","K11366//ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12]","NP_958443.1//ubiquitin carboxyl-terminal hydrolase 51 [Homo sapiens]","3//A2MP1"]
[201164,2591,8.75,5.24,-0.739716205182241,{"v":5.4892301142182e-07,"d":"5.49E-07"},"*",{"v":8.7249e-08,"d":"8.72E-08"},"PLD6","GO:0016021//integral component of membrane;GO:0005741//mitochondrial outer membrane","GO:0046872//metal ion binding;GO:0035755//cardiolipin hydrolase activity;GO:0042803//protein homodimerization activity;GO:0004519//endonuclease activity","GO:0008053//mitochondrial fusion;GO:0016042//lipid catabolic process;GO:0010636//positive regulation of mitochondrial fusion;GO:0051321//meiotic cell cycle;GO:0043046//DNA methylation involved in gamete generation;GO:0030719//P granule organization;GO:0007286//spermatid development;GO:0034587//piRNA metabolic process;GO:0006654//phosphatidic acid biosynthetic process","K16862//mitochondrial cardiolipin hydrolase [EC:3.1.4.-]","XP_003808818.1//PREDICTED: mitochondrial cardiolipin hydrolase [Pan paniscus]","3//A2MP1"]
[79807,4098,5.82,3.49,-0.737792116698632,{"v":1.28272454042918E-7,"d":"1.28E-07"},"*",{"v":1.871008e-08,"d":"1.87E-08"},"GSTCD","GO:0070062//extracellular exosome;GO:0005737//cytoplasm","GO:0016740//transferase activity","NA","K15696//RING finger protein 113B;K17985//activating molecule in BECN1-regulated autophagy protein 1;K06824//nephronectin","NP_001026890.2//glutathione S-transferase C-terminal domain-containing protein isoform 1 [Homo sapiens];NP_079027.2//glutathione S-transferase C-terminal domain-containing protein isoform 2 [Homo sapiens]","3//A2MP1"]
[8174,1285,0.1,0.06,-0.736965594166206,0.733487956900975,"*",0.626454,"MADCAM1","GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0098640//integrin binding involved in cell-matrix adhesion","GO:0043113//receptor clustering;GO:0007165//signal transduction;GO:0050901//leukocyte tethering or rolling;GO:0007568//aging;GO:0007160//cell-matrix adhesion;GO:0007155//cell adhesion;GO:0030198//extracellular matrix organization;GO:0034113//heterotypic cell-cell adhesion;GO:0006955//immune response;GO:0007229//integrin-mediated signaling pathway;GO:0002687//positive regulation of leukocyte migration;GO:0050776//regulation of immune response","K06779//mucosal vascular addressin cell adhesion molecule 1","NP_570116.2//mucosal addressin cell adhesion molecule 1 isoform a precursor [Homo sapiens];NP_570118.1//mucosal addressin cell adhesion molecule 1 isoform b precursor [Homo sapiens]","2//1"]
[55521,4240,0.15,0.09,-0.736965594166206,0.582628472521828,"*",0.426084,"TRIM36","GO:0070062//extracellular exosome;GO:0005856//cytoskeleton;GO:0005829//cytosol;GO:0001669//acrosomal vesicle","GO:0008270//zinc ion binding;GO:0004842//ubiquitin-protein transferase activity","GO:0007340//acrosome reaction;GO:0051726//regulation of cell cycle;GO:0000209//protein polyubiquitination","K12013//tripartite motif-containing protein 36 [EC:2.3.2.27];K09291//nucleoprotein TPR","NP_001287688.1//E3 ubiquitin-protein ligase TRIM36 isoform 5 [Homo sapiens];NP_001017398.1//E3 ubiquitin-protein ligase TRIM36 isoform 3 [Homo sapiens];NP_061170.2//E3 ubiquitin-protein ligase TRIM36 isoform 1 [Homo sapiens];KFD45978.1//hypothetical protein M513_13134 [Trichuris suis]","1//3;3//A2MP1"]
[56999,7251,0.85,0.51,-0.736965594166206,0.0157218772622528,"*",0.00572322,"ADAMTS9","GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0009986//cell surface;GO:0005578//proteinaceous extracellular matrix","GO:0008237//metallopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding","GO:0006508//proteolysis;GO:0007275//multicellular organism development;GO:0006516//glycoprotein catabolic process;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0045636//positive regulation of melanocyte differentiation","K08624//a disintegrin and metalloproteinase with thrombospondin motifs 9 [EC:3.4.24.-]","NP_891550.1//A disintegrin and metalloproteinase with thrombospondin motifs 9 isoform 1 preproprotein [Homo sapiens];NP_001305710.1//A disintegrin and metalloproteinase with thrombospondin motifs 9 isoform 4 precursor [Homo sapiens]","1//3"]
[2650,5528,0.4,0.24,-0.736965594166206,0.145816370339088,"*",0.0734924,"GCNT1","GO:0016020//membrane;GO:0005615//extracellular space;GO:0016021//integral component of membrane;GO:0031985//Golgi cisterna;GO:0005802//trans-Golgi network;GO:0000139//Golgi membrane","GO:0008375//acetylglucosaminyltransferase activity;GO:0003829//beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity","GO:0048729//tissue morphogenesis;GO:0009101//glycoprotein biosynthetic process;GO:0060352//cell adhesion molecule production;GO:0032868//response to insulin;GO:0060993//kidney morphogenesis;GO:0050901//leukocyte tethering or rolling;GO:0016266//O-glycan processing","K00727//beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase [EC:2.4.1.102]","NP_001481.2//beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase [Homo sapiens]","4;1//3"]
[51761,9355,0.05,0.03,-0.736965594166206,0.498508323513465,"*",0.345342,"ATP8A2","GO:0005768//endosome;GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0000287//magnesium ion binding;GO:0005524//ATP binding;GO:0004012//phospholipid-translocating ATPase activity","GO:0061092//positive regulation of phospholipid translocation;GO:0043588//skin development;GO:0010996//response to auditory stimulus;GO:0050908//detection of light stimulus involved in visual perception;GO:0050884//neuromuscular process controlling posture;GO:0042755//eating behavior;GO:0010976//positive regulation of neuron projection development;GO:0003011//involuntary skeletal muscle contraction;GO:0010842//retina layer formation;GO:0048666//neuron development;GO:0007409//axonogenesis;GO:0007568//aging;GO:0042472//inner ear morphogenesis;GO:0040018//positive regulation of multicellular organism growth;GO:0060052//neurofilament cytoskeleton organization","K14802//phospholipid-transporting ATPase [EC:3.6.3.1]","XP_006159595.1//PREDICTED: phospholipid-transporting ATPase IB isoform X1 [Tupaia chinensis];XP_012664962.1//PREDICTED: phospholipid-transporting ATPase IB isoform X1 [Otolemur garnettii]","1//3;5"]
[23291,4510,12.74,7.65,-0.735833624676286,{"v":1.30490723015075e-16,"d":"1.30E-16"},"*",{"v":8.1281e-18,"d":"8.13E-18"},"FBXW11","NA","NA","NA","K03362//F-box and WD-40 domain protein 1/11","XP_006978940.2//PREDICTED: F-box/WD repeat-containing protein 11 isoform X3 [Peromyscus maniculatus bairdii];XP_015853092.1//PREDICTED: F-box/WD repeat-containing protein 11 isoform X2 [Peromyscus maniculatus bairdii];XP_006978941.2//PREDICTED: F-box/WD repeat-containing protein 11 isoform X4 [Peromyscus maniculatus bairdii]","2//1"]
[134147,4047,8.13,4.89,-0.733420887122794,{"v":1.26779434675468e-09,"d":"1.27E-09"},"*",{"v":1.442876e-10,"d":"1.44E-10"},"CMBL","GO:0070062//extracellular exosome;GO:0005829//cytosol","GO:0016787//hydrolase activity","GO:0006805//xenobiotic metabolic process","K01061//carboxymethylenebutenolidase [EC:3.1.1.45]","NP_620164.1//carboxymethylenebutenolidase homolog [Homo sapiens]","3//A2MP1"]
[11196,7306,8.92,5.37,-0.732121621934892,{"v":2.53193762018349e-18,"d":"2.53E-18"},"*",{"v":1.382152e-19,"d":"1.38E-19"},"SEC23IP","GO:0043231//intracellular membrane-bounded organelle;GO:0005783//endoplasmic reticulum;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005737//cytoplasm;GO:0000139//Golgi membrane;GO:0030134//COPII-coated ER to Golgi transport vesicle;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0012507//ER to Golgi transport vesicle membrane","GO:0004620//phospholipase activity;GO:0003723//RNA binding;GO:0046872//metal ion binding","GO:0006886//intracellular protein transport;GO:0048208//COPII vesicle coating;GO:0007030//Golgi organization;GO:0006888//ER to Golgi vesicle-mediated transport","K16545//phospholipase DDHD2 [EC:3.1.1.-]","NP_009121.1//SEC23-interacting protein [Homo sapiens]","3//A2MP1"]
[1831,2087,6.7,4.04,-0.72980580259334,2.1514971052094E-4,"*",{"v":5.27436e-05,"d":"5.27E-05"},"TSC22D3","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0003700//DNA binding transcription factor activity;GO:0043426//MRF binding","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006970//response to osmotic stress;GO:0006355//regulation of transcription, DNA-templated;GO:0034220//ion transmembrane transport;GO:0070236//negative regulation of activation-induced cell death of T cells;GO:0048642//negative regulation of skeletal muscle tissue development","K15033//peptidyl-tRNA hydrolase ICT1 [EC:3.1.1.29]","NP_004080.2//TSC22 domain family protein 3 isoform 2 [Homo sapiens];EAX02707.1//TSC22 domain family, member 3, isoform CRA_b, partial [Homo sapiens];XP_007990698.1//PREDICTED: TSC22 domain family protein 3 isoform X1 [Chlorocebus sabaeus]","1//3;3//A2MP1;2//1"]
[1032,1175,3.73,2.25,-0.729250629038201,0.0438582701037126,"*",0.0182665,"CDKN2D","GO:0097129//cyclin D2-CDK4 complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0004861//cyclin-dependent protein serine/threonine kinase inhibitor activity;GO:0016301//kinase activity;GO:0019901//protein kinase binding","GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0030308//negative regulation of cell growth;GO:1902807//negative regulation of cell cycle G1/S phase transition;GO:0009411//response to UV;GO:0033280//response to vitamin D;GO:0032526//response to retinoic acid;GO:0042326//negative regulation of phosphorylation;GO:0007050//cell cycle arrest;GO:1902230//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage;GO:0000731//DNA synthesis involved in DNA repair;GO:0007605//sensory perception of sound;GO:0000082//G1/S transition of mitotic cell cycle;GO:0048102//autophagic cell death;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0008285//negative regulation of cell proliferation","K06623//cyclin-dependent kinase inhibitor 2D","NP_001791.1//cyclin-dependent kinase 4 inhibitor D [Homo sapiens]","3//A2MP1;2//1"]
[399687,7183,11.59,7,-0.727453739174143,{"v":6.38721764435946e-26,"d":"6.39E-26"},"*",{"v":2.09122e-27,"d":"2.09E-27"},"MYO18A","GO:0016020//membrane;GO:0009986//cell surface;GO:0016459//myosin complex;GO:0042641//actomyosin;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005802//trans-Golgi network;GO:0000139//Golgi membrane","GO:0043531//ADP binding;GO:0051015//actin filament binding;GO:0003723//RNA binding;GO:0003677//DNA binding;GO:0005524//ATP binding;GO:0003774//motor activity;GO:0008094//DNA-dependent ATPase activity","GO:1903028//positive regulation of opsonization;GO:0016477//cell migration;GO:0031032//actomyosin structure organization;GO:0043030//regulation of macrophage activation;GO:0043066//negative regulation of apoptotic process;GO:0007030//Golgi organization;GO:0006259//DNA metabolic process;GO:0050714//positive regulation of protein secretion;GO:0048194//Golgi vesicle budding;GO:0090164//asymmetric Golgi ribbon formation;GO:0090161//Golgi ribbon formation","K10362//myosin XVIII","NP_001333696.1//unconventional myosin-XVIIIa isoform e [Homo sapiens];NP_001333695.1//unconventional myosin-XVIIIa isoform d [Homo sapiens];BAD66838.1//KIAA0216 splice variant 2, partial [Homo sapiens];NP_001333694.1//unconventional myosin-XVIIIa isoform c [Homo sapiens];NP_510880.2//unconventional myosin-XVIIIa isoform a [Homo sapiens];NP_976063.1//unconventional myosin-XVIIIa isoform b [Homo sapiens]","1//3;3//A2MP1"]
[6197,7723,12.72,7.69,-0.726043167322529,{"v":9.97829855555555e-27,"d":"9.98E-27"},"*",{"v":3.14828E-28,"d":"3.15E-28"},"RPS6KA3","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005737//cytoplasm","GO:0000287//magnesium ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process;GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0016301//kinase activity;GO:0019901//protein kinase binding","GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007165//signal transduction;GO:0032496//response to lipopolysaccharide;GO:0030307//positive regulation of cell growth;GO:0043066//negative regulation of apoptotic process;GO:0035556//intracellular signal transduction;GO:0002224//toll-like receptor signaling pathway;GO:0007417//central nervous system development;GO:0043620//regulation of DNA-templated transcription in response to stress;GO:0043555//regulation of translation in response to stress;GO:0018105//peptidyl-serine phosphorylation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0001501//skeletal system development;GO:0007049//cell cycle;GO:0045597//positive regulation of cell differentiation","K04373//ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]","NP_004577.1//ribosomal protein S6 kinase alpha-3 [Homo sapiens]","2//1"]
[7832,2718,5.52,3.34,-0.724820164304117,{"v":9.14420813132695e-05,"d":"9.14E-05"},"*",{"v":2.09228e-05,"d":"2.09E-05"},"BTG2","GO:0070062//extracellular exosome;GO:0005829//cytosol","GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0009952//anterior/posterior pattern specification;GO:0014070//response to organic cyclic compound;GO:0051602//response to electrical stimulus;GO:0017148//negative regulation of translation;GO:0031175//neuron projection development;GO:0006974//cellular response to DNA damage stimulus;GO:0008285//negative regulation of cell proliferation;GO:0009612//response to mechanical stimulus;GO:0006281//DNA repair;GO:0043434//response to peptide hormone;GO:0021954//central nervous system neuron development;GO:0043524//negative regulation of neuron apoptotic process;GO:0006479//protein methylation;GO:0006351//transcription, DNA-templated;GO:0021542//dentate gyrus development;GO:2000178//negative regulation of neural precursor cell proliferation;GO:0035914//skeletal muscle cell differentiation;GO:0008306//associative learning;GO:0060213//positive regulation of nuclear-transcribed mRNA poly(A) tail shortening;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest","K14443//protein Tob/BTG","NP_006754.1//protein BTG2 [Homo sapiens]","2//1"]
[55342,6419,4.97,3.01,-0.723482364802584,{"v":3.58308081044386e-09,"d":"3.58E-09"},"*",{"v":4.29548e-10,"d":"4.30E-10"},"STRBP","GO:0005634//nucleus;GO:0015630//microtubule cytoskeleton;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0003677//DNA binding;GO:0003725//double-stranded RNA binding;GO:0003727//single-stranded RNA binding","GO:0007275//multicellular organism development;GO:0007286//spermatid development;GO:0007283//spermatogenesis;GO:0007638//mechanosensory behavior","K13200//spermatid perinuclear RNA-binding protein","NP_060857.2//spermatid perinuclear RNA-binding protein isoform 1 [Homo sapiens];EPQ16850.1//Spermatid perinuclear RNA-binding protein [Myotis brandtii]","1//3;4"]
[84441,7115,0.94,0.57,-0.721698837512896,0.0104930434413247,"*",3.64964E-3,"MAML2","NA","NA","NA","K06061//mastermind","XP_003910630.2//mastermind-like protein 2 isoform X1 [Papio anubis]","3//A2MP1"]
[6821,2564,9.62,5.84,-0.720068524890025,{"v":8.67938363506028e-06,"d":"8.68E-06"},"*",{"v":1.667524e-06,"d":"1.67E-06"},"SUOX","GO:0005759//mitochondrial matrix;GO:0005758//mitochondrial intermembrane space;GO:0005739//mitochondrion","GO:0043546//molybdopterin cofactor binding;GO:0020037//heme binding;GO:0008482//sulfite oxidase activity;GO:0030151//molybdenum ion binding;GO:0016491//oxidoreductase activity","GO:0042128//nitrate assimilation;GO:0070221//sulfide oxidation, using sulfide:quinone oxidoreductase","K00387//sulfite oxidase [EC:1.8.3.1]","XP_005269169.1//PREDICTED: sulfite oxidase, mitochondrial isoform X1 [Homo sapiens];XP_017801428.1//sulfite oxidase, mitochondrial isoform X1 [Papio anubis]","1//3;2//1"]
[5796,6104,4.94,3,-0.719548541088797,{"v":1.10245801509064E-8,"d":"1.10E-08"},"*",{"v":1.408612E-9,"d":"1.41E-09"},"PTPRK","GO:0043231//intracellular membrane-bounded organelle;GO:0030425//dendrite;GO:0030424//axon;GO:0031256//leading edge membrane;GO:0030054//cell junction;GO:0001750//photoreceptor outer segment;GO:0005912//adherens junction;GO:0043025//neuronal cell body;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0045295//gamma-catenin binding;GO:0005001//transmembrane receptor protein tyrosine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0019901//protein kinase binding;GO:0008013//beta-catenin binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0010839//negative regulation of keratinocyte proliferation;GO:0016477//cell migration;GO:0007165//signal transduction;GO:0045786//negative regulation of cell cycle;GO:0034614//cellular response to reactive oxygen species;GO:0030336//negative regulation of cell migration;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0034644//cellular response to UV;GO:0007155//cell adhesion;GO:0006470//protein dephosphorylation;GO:0031175//neuron projection development;GO:0034394//protein localization to cell surface;GO:0048041//focal adhesion assembly;GO:0008285//negative regulation of cell proliferation","K06776//receptor-type tyrosine-protein phosphatase kappa [EC:3.1.3.48]","NP_001278910.1//receptor-type tyrosine-protein phosphatase kappa isoform c precursor [Homo sapiens];XP_010341284.1//PREDICTED: receptor-type tyrosine-protein phosphatase kappa isoform X7 [Saimiri boliviensis boliviensis];NP_001278911.1//receptor-type tyrosine-protein phosphatase kappa isoform d precursor [Homo sapiens];NP_001129120.1//receptor-type tyrosine-protein phosphatase kappa isoform a precursor [Homo sapiens];XP_003353263.1//receptor-type tyrosine-protein phosphatase kappa isoform X15 [Sus scrofa];NP_001278912.1//receptor-type tyrosine-protein phosphatase kappa isoform e [Homo sapiens]","1//3;3//A2MP1;2//1"]
[54558,4976,0.51,0.31,-0.718229031584621,0.142487920539057,"*",0.0714848,"SPATA6","GO:0005576//extracellular region;GO:0097224//sperm connecting piece","GO:0032027//myosin light chain binding","GO:0030154//cell differentiation;GO:0007275//multicellular organism development;GO:0007283//spermatogenesis;GO:0044458//motile cilium assembly","NA","NP_001273167.1//spermatogenesis-associated protein 6 isoform 2 [Homo sapiens];NP_001273168.1//spermatogenesis-associated protein 6 isoform 3 [Homo sapiens];NP_061946.1//spermatogenesis-associated protein 6 isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[23035,8380,2.22,1.35,-0.717600269299275,{"v":1.14843309172259E-5,"d":"1.15E-05"},"*",{"v":2.24956e-06,"d":"2.25E-06"},"PHLPP2","GO:0005634//nucleus;GO:0001917//photoreceptor inner segment;GO:0005829//cytosol;GO:0042622//photoreceptor outer segment membrane;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0004722//protein serine/threonine phosphatase activity","GO:0007165//signal transduction;GO:0021766//hippocampus development;GO:0006470//protein dephosphorylation","K16340//PH domain and leucine-rich repeat-containing protein phosphatase [EC:3.1.3.16]","NP_001275932.1//PH domain leucine-rich repeat-containing protein phosphatase 2 isoform 2 [Homo sapiens];NP_055835.2//PH domain leucine-rich repeat-containing protein phosphatase 2 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[54361,3905,0.23,0.14,-0.716207033999409,0.382669878587859,"*",0.239534,"WNT4","GO:0005578//proteinaceous extracellular matrix","GO:0005102//receptor binding","GO:0007275//multicellular organism development;GO:0016055//Wnt signaling pathway","K00408//wingless-type MMTV integration site family, member 4","XP_524597.4//PREDICTED: protein Wnt-4 [Pan troglodytes]",4]
[5962,4433,25.73,15.67,-0.71544627726122,{"v":4.54472756788991e-30,"d":"4.54E-30"},"*",{"v":1.240454E-31,"d":"1.24E-31"},"RDX","GO:0005615//extracellular space;GO:0016324//apical plasma membrane;GO:0071944//cell periphery;GO:0030496//midbody;GO:0030864//cortical actin cytoskeleton;GO:0005913//cell-cell adherens junction;GO:0032420//stereocilium;GO:0005886//plasma membrane;GO:0005856//cytoskeleton;GO:0070062//extracellular exosome;GO:0030315//T-tubule;GO:0051286//cell tip;GO:0005925//focal adhesion;GO:0043209//myelin sheath;GO:0030027//lamellipodium;GO:0005902//microvillus;GO:0030175//filopodium;GO:0001726//ruffle;GO:0032154//cleavage furrow","GO:0003779//actin binding;GO:0003723//RNA binding;GO:0051018//protein kinase A binding;GO:0019904//protein domain specific binding;GO:0051117//ATPase binding;GO:0042803//protein homodimerization activity;GO:0045296//cadherin binding","GO:2000643//positive regulation of early endosome to late endosome transport;GO:0030335//positive regulation of cell migration;GO:1902966//positive regulation of protein localization to early endosome;GO:0032231//regulation of actin filament bundle assembly;GO:0045176//apical protein localization;GO:1900027//regulation of ruffle assembly;GO:1903392//negative regulation of adherens junction organization;GO:1902115//regulation of organelle assembly;GO:0036120//cellular response to platelet-derived growth factor stimulus;GO:0045184//establishment of protein localization;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle;GO:1903364//positive regulation of cellular protein catabolic process;GO:0032487//regulation of Rap protein signal transduction;GO:0072659//protein localization to plasma membrane;GO:0010737//protein kinase A signaling;GO:0008361//regulation of cell size;GO:0051016//barbed-end actin filament capping;GO:0008360//regulation of cell shape;GO:0010628//positive regulation of gene expression;GO:0030033//microvillus assembly;GO:0045792//negative regulation of cell size;GO:0034111//negative regulation of homotypic cell-cell adhesion;GO:0043087//regulation of GTPase activity;GO:0061028//establishment of endothelial barrier;GO:0034260//negative regulation of GTPase activity;GO:0097067//cellular response to thyroid hormone stimulus","K05762//radixin","XP_021526788.1//LOW QUALITY PROTEIN: radixin [Aotus nancymaae];NP_001247425.1//radixin isoform 5 [Homo sapiens];BAE40352.1//unnamed protein product, partial [Mus musculus];XP_003992383.1//PREDICTED: radixin isoform X1 [Felis catus];NP_001247423.1//radixin isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[84188,5292,11.37,6.93,-0.714304996755034,{"v":3.23711460766962E-16,"d":"3.24E-16"},"*",{"v":2.06094e-17,"d":"2.06E-17"},"FAR1","GO:0005779//integral component of peroxisomal membrane;GO:0005777//peroxisome","GO:0080019//fatty-acyl-CoA reductase (alcohol-forming) activity;GO:0102965//alcohol-forming fatty acyl-CoA reductase activity","GO:0008611//ether lipid biosynthetic process;GO:0035336//long-chain fatty-acyl-CoA metabolic process;GO:0010025//wax biosynthetic process;GO:0046474//glycerophospholipid biosynthetic process","K13356//alcohol-forming fatty acyl-CoA reductase [EC:1.2.1.84]","XP_012636183.1//fatty acyl-CoA reductase 1 isoform X4 [Microcebus murinus]",5]
[8916,4823,1,0.61,-0.713118852211838,0.013363162043387,"*",0.00478176,"HERC3","GO:0005829//cytosol;GO:0031410//cytoplasmic vesicle;GO:0005737//cytoplasm","GO:0061630//ubiquitin protein ligase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0016874//ligase activity","NA","K10614//E3 ubiquitin-protein ligase HERC3 [EC:2.3.2.26]","NP_001305434.1//probable E3 ubiquitin-protein ligase HERC3 isoform 3 [Homo sapiens];XP_004665475.1//PREDICTED: probable E3 ubiquitin-protein ligase HERC3 [Jaculus jaculus];XP_007184167.1//PREDICTED: probable E3 ubiquitin-protein ligase HERC3 isoform X4 [Balaenoptera acutorostrata scammoni]","1//3;2//1"]
[4090,6949,5.7,3.48,-0.711874613203376,{"v":4.41482723276983e-11,"d":"4.41E-11"},"*",{"v":4.25066e-12,"d":"4.25E-12"},"SMAD5","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005622//intracellular;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043234//protein complex;GO:0005667//transcription factor complex;GO:0016021//integral component of membrane;GO:0071141//SMAD protein complex","GO:0003677//DNA binding;GO:0005057//signal transducer activity, downstream of receptor;GO:0031625//ubiquitin protein ligase binding;GO:0017151//DEAD/H-box RNA helicase binding;GO:0046872//metal ion binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0030618//transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity;GO:0003700//DNA binding transcription factor activity","GO:0051216//cartilage development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0071407//cellular response to organic cyclic compound;GO:0009880//embryonic pattern specification;GO:0060048//cardiac muscle contraction;GO:0060348//bone development;GO:0007165//signal transduction;GO:0006468//protein phosphorylation;GO:0006351//transcription, DNA-templated;GO:0030509//BMP signaling pathway;GO:0045669//positive regulation of osteoblast differentiation;GO:0030218//erythrocyte differentiation;GO:1901522//positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus;GO:0060395//SMAD protein signal transduction;GO:0007281//germ cell development;GO:0002051//osteoblast fate commitment;GO:0001880//Mullerian duct regression;GO:0001657//ureteric bud development","K16790//mothers against decapentaplegic homolog 5","ELR59268.1//Mothers against decapentaplegic-like protein 5, partial [Bos mutus]","6;2//1"]
[55125,7995,2.52,1.54,-0.710493382805015,{"v":4.59055065487929e-06,"d":"4.59E-06"},"*",{"v":8.45174e-07,"d":"8.45E-07"},"CEP192","GO:0005814//centriole;GO:0000242//pericentriolar material;GO:0005829//cytosol;GO:0005813//centrosome","GO:0019902//phosphatase binding","GO:0010389//regulation of G2/M transition of mitotic cell cycle;GO:0097711//ciliary basal body-plasma membrane docking;GO:0051225//spindle assembly;GO:0051298//centrosome duplication;GO:0010923//negative regulation of phosphatase activity;GO:0000086//G2/M transition of mitotic cell cycle","K16725//centrosomal protein CEP192","NP_115518.3//centrosomal protein of 192 kDa [Homo sapiens]","3//A2MP1"]
[9805,5191,24.2,14.8,-0.709409871645645,{"v":2.96605956033994e-35,"d":"2.97E-35"},"*",{"v":6.55452e-37,"d":"6.55E-37"},"SCRN1","GO:0005634//nucleus;GO:0031965//nuclear membrane;GO:0005737//cytoplasm","GO:0016805//dipeptidase activity","GO:0006887//exocytosis","K14358//secernin","NP_055581.3//secernin-1 isoform a [Homo sapiens];NP_001138986.1//secernin-1 isoform b [Homo sapiens]","4;1//3"]
[56101,2457,0.67,0.41,-0.708537185839689,0.000746696408088235,"*",2.03432E-4,"PCDHGB5","GO:0070062//extracellular exosome;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005509//calcium ion binding","GO:0007399//nervous system development;GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007267//cell-cell signaling","K16496//protocadherin gamma subfamily B","NP_061748.1//protocadherin gamma-B5 isoform 1 precursor [Homo sapiens];NP_115270.1//protocadherin gamma-B5 isoform 2 precursor [Homo sapiens]","1//3;2//1"]
[80329,2958,0.93,0.57,-0.70626879694329,0.0404534939650721,"*",0.01667624,"ULBP1","GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0015629//actin cytoskeleton;GO:0046658//anchored component of plasma membrane;GO:0005886//plasma membrane","GO:0046703//natural killer cell lectin-like receptor binding","GO:0030101//natural killer cell activation;GO:0042267//natural killer cell mediated cytotoxicity;GO:0016032//viral process;GO:0050776//regulation of immune response","K07986//UL16 binding protein","NP_079494.1//NKG2D ligand 1 isoform 1 precursor [Homo sapiens];KRX57831.1//LINE-1 reverse transcriptase -like protein [Trichinella sp. T6]","1//3;3//A2MP1"]
[83891,3331,2.72,1.67,-0.703758548776287,0.00384788083829956,"*",1.21261E-3,"SNX25","NA","NA","NA","K17887//sorting nexin-25","XP_005263324.1//PREDICTED: sorting nexin-25 isoform X6 [Homo sapiens]","1//3"]
[9779,6653,9.69,5.95,-0.703606997219775,{"v":1.39224797248255e-16,"d":"1.39E-16"},"*",{"v":8.74186e-18,"d":"8.74E-18"},"TBC1D5","GO:0043231//intracellular membrane-bounded organelle;GO:0010008//endosome membrane;GO:0030904//retromer complex;GO:1990316//Atg1/ULK1 kinase complex;GO:0030122//AP-2 adaptor complex;GO:0005622//intracellular;GO:0012505//endomembrane system;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0005776//autophagosome","GO:0035612//AP-2 adaptor complex binding;GO:1905394//retromer complex binding;GO:0017137//Rab GTPase binding;GO:0005096//GTPase activator activity","GO:0090630//activation of GTPase activity;GO:0042147//retrograde transport, endosome to Golgi;GO:0002092//positive regulation of receptor internalization;GO:0006886//intracellular protein transport;GO:0042594//response to starvation;GO:0006914//autophagy;GO:0031338//regulation of vesicle fusion;GO:0016236//macroautophagy","K18469//TBC1 domain family member 5","NP_001336010.1//TBC1 domain family member 5 isoform c [Homo sapiens];NP_001127853.1//TBC1 domain family member 5 isoform a [Homo sapiens];XP_009443270.1//PREDICTED: TBC1 domain family member 5 isoform X1 [Pan troglodytes];NP_055559.1//TBC1 domain family member 5 isoform b [Homo sapiens]","1//3;2//1"]
[659,12086,3.19,1.96,-0.702702769649661,{"v":1.76592472478632E-10,"d":"1.77E-10"},"*",{"v":1.810808e-11,"d":"1.81E-11"},"BMPR2","GO:0005654//nucleoplasm;GO:0005615//extracellular space;GO:0016324//apical plasma membrane;GO:0009925//basal plasma membrane;GO:0005901//caveola;GO:0009986//cell surface;GO:0005913//cell-cell adherens junction;GO:0005887//integral component of plasma membrane","GO:0098821//BMP receptor activity;GO:0005524//ATP binding;GO:0016362//activin receptor activity, type II;GO:0004702//signal transducer, downstream of receptor, with serine/threonine kinase activity;GO:0004675//transmembrane receptor protein serine/threonine kinase activity;GO:0036122//BMP binding","GO:0009952//anterior/posterior pattern specification;GO:0009267//cellular response to starvation;GO:0014916//regulation of lung blood pressure;GO:0002063//chondrocyte development;GO:0010595//positive regulation of endothelial cell migration;GO:0030513//positive regulation of BMP signaling pathway;GO:0060350//endochondral bone morphogenesis;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0001938//positive regulation of endothelial cell proliferation;GO:0001935//endothelial cell proliferation;GO:0030166//proteoglycan biosynthetic process;GO:0030308//negative regulation of cell growth;GO:0061036//positive regulation of cartilage development;GO:0003085//negative regulation of systemic arterial blood pressure;GO:0030509//BMP signaling pathway;GO:0045669//positive regulation of osteoblast differentiation;GO:0060840//artery development;GO:0006366//transcription from RNA polymerase II promoter;GO:2000279//negative regulation of DNA biosynthetic process;GO:0001974//blood vessel remodeling;GO:1902731//negative regulation of chondrocyte proliferation;GO:0030501//positive regulation of bone mineralization;GO:0060413//atrial septum morphogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0072577//endothelial cell apoptotic process","K04671//bone morphogenetic protein receptor type-2 [EC:2.7.11.30]","XP_003254004.1//PREDICTED: bone morphogenetic protein receptor type-2 [Nomascus leucogenys]",6]
[9695,6162,8.11,4.99,-0.700662098880012,{"v":3.50925391277259e-13,"d":"3.51E-13"},"*",{"v":2.82076E-14,"d":"2.82E-14"},"EDEM1","GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0044322//endoplasmic reticulum quality control compartment;GO:0000139//Golgi membrane","GO:0051787//misfolded protein binding;GO:0004571//mannosyl-oligosaccharide 1,2-alpha-mannosidase activity;GO:0005509//calcium ion binding","GO:0008152//metabolic process;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0006491//N-glycan processing;GO:0097466//ubiquitin-dependent glycoprotein ERAD pathway;GO:1904382//mannose trimming involved in glycoprotein ERAD pathway;GO:0036498//IRE1-mediated unfolded protein response;GO:1904154//positive regulation of retrograde protein transport, ER to cytosol;GO:0036510//trimming of terminal mannose on C branch","K10084//ER degradation enhancer, mannosidase alpha-like 1","NP_055489.1//ER degradation-enhancing alpha-mannosidase-like protein 1 [Homo sapiens]","2//1"]
[59341,3012,0.13,0.08,-0.700439718141092,0.63142824970919,"*",0.50972,"TRPV4","GO:0005929//cilium;GO:0009986//cell surface;GO:0016324//apical plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005912//adherens junction","GO:0051015//actin filament binding;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0015275//stretch-activated, cation-selective, calcium channel activity;GO:0042169//SH2 domain binding;GO:0019901//protein kinase binding;GO:0003779//actin binding;GO:0043014//alpha-tubulin binding;GO:0005034//osmosensor activity;GO:0005516//calmodulin binding","GO:0030103//vasopressin secretion;GO:0046330//positive regulation of JNK cascade;GO:0071642//positive regulation of macrophage inflammatory protein 1 alpha production;GO:0042593//glucose homeostasis;GO:0007015//actin filament organization;GO:0043117//positive regulation of vascular permeability;GO:2000778//positive regulation of interleukin-6 secretion;GO:0002024//diet induced thermogenesis;GO:0071651//positive regulation of chemokine (C-C motif) ligand 5 production;GO:0010628//positive regulation of gene expression;GO:0047484//regulation of response to osmotic stress;GO:0097497//blood vessel endothelial cell delamination;GO:1903759//signal transduction involved in regulation of aerobic respiration;GO:0007043//cell-cell junction assembly;GO:0071477//cellular hypotonic salinity response;GO:0010759//positive regulation of macrophage chemotaxis;GO:0050729//positive regulation of inflammatory response;GO:0071639//positive regulation of monocyte chemotactic protein-1 production;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0060351//cartilage development involved in endochondral bone morphogenesis;GO:2000340//positive regulation of chemokine (C-X-C motif) ligand 1 production;GO:0031532//actin cytoskeleton reorganization;GO:0032868//response to insulin;GO:0042538//hyperosmotic salinity response;GO:0050891//multicellular organismal water homeostasis;GO:0034605//cellular response to heat;GO:0007231//osmosensory signaling pathway;GO:0070509//calcium ion import;GO:2000507//positive regulation of energy homeostasis;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:1903444//negative regulation of brown fat cell differentiation;GO:0070374//positive regulation of ERK1 and ERK2 cascade","K04973//transient receptor potential cation channel subfamily V member 4","NP_001170902.1//transient receptor potential cation channel subfamily V member 4 isoform d [Homo sapiens];XP_011536935.2//PREDICTED: transient receptor potential cation channel subfamily V member 4 isoform X5 [Homo sapiens];XP_011536933.2//PREDICTED: transient receptor potential cation channel subfamily V member 4 isoform X2 [Homo sapiens];XP_011536934.2//PREDICTED: transient receptor potential cation channel subfamily V member 4 isoform X4 [Homo sapiens];XP_011536932.2//PREDICTED: transient receptor potential cation channel subfamily V member 4 isoform X1 [Homo sapiens]","1//3;4;2//1"]
[55251,3897,3.15,1.94,-0.699295176200151,0.000434174473357401,"*",1.129332E-4,"PCMTD2","NA","GO:0004719//protein-L-isoaspartate (D-aspartate) O-methyltransferase activity","NA","K00573//protein-L-isoaspartate(D-aspartate) O-methyltransferase [EC:2.1.1.77]","XP_008008332.1//PREDICTED: protein-L-isoaspartate O-methyltransferase domain-containing protein 2 [Chlorocebus sabaeus]","1//3;2//1"]
[5194,4524,8.53,5.26,-0.697482942025988,{"v":2.51895632095808e-10,"d":"2.52E-10"},"*",{"v":2.63344e-11,"d":"2.63E-11"},"PEX13","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005779//integral component of peroxisomal membrane;GO:0005777//peroxisome;GO:0005778//peroxisomal membrane","NA","GO:0021795//cerebral cortex cell migration;GO:0007626//locomotory behavior;GO:0001561//fatty acid alpha-oxidation;GO:0001764//neuron migration;GO:0016560//protein import into peroxisome matrix, docking;GO:0001967//suckling behavior;GO:0060152//microtubule-based peroxisome localization","K13344//peroxin-13","XP_012332678.1//peroxisome biogenesis factor 13 isoform X1 [Aotus nancymaae]","3//A2MP1"]
[80852,7721,0.6,0.37,-0.697437229979569,0.0452636563764424,"*",0.0189085,"GRIP2","GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0030159//receptor signaling complex scaffold activity","NA","K20251//glutamate receptor-interacting protein","NP_001073892.3//glutamate receptor-interacting protein 2 [Homo sapiens]","3//A2MP1"]
[22878,6283,3.82,2.36,-0.694785778673907,{"v":1.03492332012012E-6,"d":"1.03E-06"},"*",{"v":1.725952E-7,"d":"1.73E-07"},"TRAPPC8","GO:1990072//TRAPPIII protein complex;GO:0005829//cytosol;GO:0031410//cytoplasmic vesicle;GO:0000407//phagophore assembly site;GO:0030008//TRAPP complex","GO:0017112//Rab guanyl-nucleotide exchange factor activity","GO:0034497//protein localization to phagophore assembly site;GO:0030242//autophagy of peroxisome;GO:0044804//autophagy of nucleus;GO:0007030//Golgi organization;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0061024//membrane organization","K20305//trafficking protein particle complex subunit 8","NP_055754.2//trafficking protein particle complex subunit 8 [Homo sapiens]","3//A2MP1"]
[84775,4295,1.94,1.2,-0.693022246578609,0.00617402530472755,"*",2.03572E-3,"ZNF607","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","NP_001166148.1//zinc finger protein 607 isoform 2 [Homo sapiens];NP_116078.4//zinc finger protein 607 isoform 1 [Homo sapiens]","4;1//3"]
[113,5879,4.51,2.79,-0.692862311426193,{"v":2.45754656553998e-07,"d":"2.46E-07"},"*",{"v":3.73232E-8,"d":"3.73E-08"},"ADCY7","GO:0005622//intracellular;GO:0016021//integral component of membrane;GO:0008074//guanylate cyclase complex, soluble;GO:0005886//plasma membrane","GO:0016849//phosphorus-oxygen lyase activity;GO:0046872//metal ion binding;GO:0005524//ATP binding;GO:0000166//nucleotide binding;GO:0004016//adenylate cyclase activity;GO:0004383//guanylate cyclase activity","GO:0071361//cellular response to ethanol;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0071377//cellular response to glucagon stimulus;GO:0007165//signal transduction;GO:0060135//maternal process involved in female pregnancy;GO:0009190//cyclic nucleotide biosynthetic process;GO:0035556//intracellular signal transduction;GO:0006182//cGMP biosynthetic process;GO:0007190//activation of adenylate cyclase activity;GO:0034199//activation of protein kinase A activity;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0030819//positive regulation of cAMP biosynthetic process;GO:0003091//renal water homeostasis","K08047//adenylate cyclase 7 [EC:4.6.1.1]","NP_001105.1//adenylate cyclase type 7 isoform 1 [Homo sapiens];NP_001272986.1//adenylate cyclase type 7 isoform 2 [Homo sapiens]","1//3;4"]
[7112,3956,59.58,36.9,-0.691207307301772,{"v":7.59559850843373e-62,"d":"7.60E-62"},"*",{"v":7.89326E-64,"d":"7.89E-64"},"TMPO","GO:0016020//membrane;GO:0031965//nuclear membrane;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0000785//chromatin;GO:0005737//cytoplasm;GO:0016021//integral component of membrane;GO:0005637//nuclear inner membrane","GO:0003677//DNA binding;GO:0005521//lamin binding;GO:0045296//cadherin binding","GO:0006355//regulation of transcription, DNA-templated","K15710//E3 ubiquitin-protein ligase SHPRH [EC:3.6.4.- 2.3.2.27];K10592//E3 ubiquitin-protein ligase HUWE1 [EC:2.3.2.26];K12569//emerin;K10858//DNA mismatch repair protein PMS2;K04613//vomeronasal 2 receptor;K18624//macrophage erythroblast attacher;K15696//RING finger protein 113B;K17985//activating molecule in BECN1-regulated autophagy protein 1","BAD92534.1//Lamina-associated polypeptide 2, isoforms beta/gamma variant, partial [Homo sapiens];NP_001027454.1//thymopoietin isoform beta [Homo sapiens];NP_003267.1//thymopoietin isoform alpha [Homo sapiens];NP_001294904.1//thymopoietin isoform delta [Homo sapiens]","1//3;2//1"]
[6713,2989,54.48,33.75,-0.690839201186516,{"v":5.89534872786885e-40,"d":"5.90E-40"},"*",{"v":1.12563E-41,"d":"1.13E-41"},"SQLE","GO:0043231//intracellular membrane-bounded organelle;GO:0005783//endoplasmic reticulum;GO:0031090//organelle membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0050660//flavin adenine dinucleotide binding;GO:0004506//squalene monooxygenase activity","GO:0016126//sterol biosynthetic process;GO:0008203//cholesterol metabolic process;GO:0010033//response to organic substance;GO:0006725//cellular aromatic compound metabolic process;GO:0006695//cholesterol biosynthetic process;GO:0045540//regulation of cholesterol biosynthetic process","K00511//squalene monooxygenase [EC:1.14.14.17]","NP_003120.2//squalene monooxygenase [Homo sapiens]","3//A2MP1"]
[57561,4334,8.45,5.24,-0.689384529632096,{"v":9.09995927272727e-10,"d":"9.10E-10"},"*",{"v":1.021424E-10,"d":"1.02E-10"},"ARRDC3","GO:0005768//endosome;GO:0005764//lysosome;GO:0005886//plasma membrane;GO:0005769//early endosome","GO:0031699//beta-3 adrenergic receptor binding","GO:0001659//temperature homeostasis;GO:0090327//negative regulation of locomotion involved in locomotory behavior;GO:0043588//skin development;GO:0031651//negative regulation of heat generation;GO:0071879//positive regulation of adrenergic receptor signaling pathway;GO:0051443//positive regulation of ubiquitin-protein transferase activity;GO:0044252//negative regulation of multicellular organismal metabolic process;GO:0060613//fat pad development","K20910//thioredoxin-interacting protein","BAF84442.1//unnamed protein product [Homo sapiens];NP_065852.1//arrestin domain-containing protein 3 isoform a [Homo sapiens];BAC65781.1//mKIAA1376 protein, partial [Mus musculus];XP_003261654.1//PREDICTED: arrestin domain-containing protein 3 [Nomascus leucogenys]","1//3;3//A2MP1"]
[55388,4559,12.23,7.59,-0.68825261311192,{"v":3.61463809924306E-14,"d":"3.61E-14"},"*",{"v":2.6905e-15,"d":"2.69E-15"},"MCM10","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031298//replication fork protection complex;GO:0005730//nucleolus","GO:0003688//DNA replication origin binding;GO:0003697//single-stranded DNA binding;GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0019899//enzyme binding","GO:0008283//cell proliferation;GO:0006260//DNA replication;GO:0000082//G1/S transition of mitotic cell cycle;GO:0006270//DNA replication initiation;GO:0006974//cellular response to DNA damage stimulus","K10736//minichromosome maintenance protein 10","NP_877428.1//protein MCM10 homolog isoform 1 [Homo sapiens];NP_060988.3//protein MCM10 homolog isoform 2 [Homo sapiens]","4;2//1"]
[143279,3541,1.24,0.77,-0.687409769691974,0.0352026560855416,"*",0.01422078,"HECTD2","GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0061630//ubiquitin protein ligase activity;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity","GO:0000209//protein polyubiquitination","K12232//E3 ubiquitin-protein ligase HECTD2 [EC:2.3.2.26]","NP_775768.3//probable E3 ubiquitin-protein ligase HECTD2 isoform b [Homo sapiens];NP_001271203.1//probable E3 ubiquitin-protein ligase HECTD2 isoform c [Homo sapiens];NP_877497.3//probable E3 ubiquitin-protein ligase HECTD2 isoform a [Homo sapiens]","1//3;3//A2MP1;2//1;5"]
[66008,6527,5.28,3.28,-0.68684211474037,{"v":3.7153243189161e-09,"d":"3.72E-09"},"*",{"v":4.46332e-10,"d":"4.46E-10"},"TRAK2","GO:0005634//nucleus;GO:0032839//dendrite cytoplasm;GO:0044295//axonal growth cone;GO:0005737//cytoplasm;GO:0043025//neuronal cell body;GO:0005739//mitochondrion;GO:0005769//early endosome;GO:0005886//plasma membrane","GO:0030911//TPR domain binding;GO:0050811//GABA receptor binding;GO:0005102//receptor binding;GO:0019894//kinesin binding;GO:0019899//enzyme binding","GO:0006605//protein targeting;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006493//protein O-linked glycosylation;GO:0050771//negative regulation of axonogenesis;GO:0008333//endosome to lysosome transport;GO:0098972//anterograde dendritic transport of mitochondrion;GO:0048813//dendrite morphogenesis","K15374//trafficking kinesin-binding protein 2","NP_055864.2//trafficking kinesin-binding protein 2 [Homo sapiens]","2//1"]
[79666,2977,2.67,1.66,-0.685656500340629,0.00857751474420317,"*",0.00291788,"PLEKHF2","GO:0005783//endoplasmic reticulum;GO:0031901//early endosome membrane;GO:0030133//transport vesicle","GO:0046872//metal ion binding","GO:0015031//protein transport","K05724//FYVE, RhoGEF and PH domain containing 5/6","NP_078889.1//pleckstrin homology domain-containing family F member 2 [Homo sapiens]","3//A2MP1"]
[9819,4806,5.32,3.31,-0.684595028693972,{"v":5.94235307692308e-07,"d":"5.94E-07"},"*",{"v":9.4786e-08,"d":"9.48E-08"},"TSC22D2","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0003700//DNA binding transcription factor activity","GO:0006970//response to osmotic stress","K22023//mucin-6;K15033//peptidyl-tRNA hydrolase ICT1 [EC:3.1.1.29]","NP_001290193.1//TSC22 domain family protein 2 isoform 2 [Homo sapiens];NP_055594.1//TSC22 domain family protein 2 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[63926,3829,4.64,2.89,-0.683055312626893,{"v":3.14822327797409e-05,"d":"3.15E-05"},"*",{"v":6.69298e-06,"d":"6.69E-06"},"ANKEF1","NA","GO:0005509//calcium ion binding","NA","K10380//ankyrin;K15503//serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B","NP_071379.3//ankyrin repeat and EF-hand domain-containing protein 1 isoform 1 [Homo sapiens]","1//3;2//1;5"]
[5128,4379,3.88,2.42,-0.681049604912533,{"v":5.34068304604889E-5,"d":"5.34E-05"},"*",{"v":1.176194e-05,"d":"1.18E-05"},"CDK17","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity","GO:0006468//protein phosphorylation","K15595//cyclin-dependent kinase 17 [EC:2.7.11.22]","DAA29629.1//TPA: PCTAIRE protein kinase 2-like [Bos taurus]","4;2//1"]
[5578,8787,18.51,11.55,-0.680412043567154,{"v":2.32303050675241E-39,"d":"2.32E-39"},"*",{"v":4.52274e-41,"d":"4.52E-41"},"PRKCA","GO:0070062//extracellular exosome;GO:0005654//nucleoplasm;GO:0005783//endoplasmic reticulum;GO:0005622//intracellular;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0005829//cytosol;GO:0031966//mitochondrial membrane;GO:0005739//mitochondrion;GO:0005886//plasma membrane","GO:0046872//metal ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0035403//histone kinase activity (H3-T6 specific);GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0008270//zinc ion binding;GO:0004697//protein kinase C activity;GO:0019899//enzyme binding;GO:0004698//calcium-dependent protein kinase C activity","GO:0007077//mitotic nuclear envelope disassembly;GO:0030335//positive regulation of cell migration;GO:0097190//apoptotic signaling pathway;GO:0045785//positive regulation of cell adhesion;GO:0010595//positive regulation of endothelial cell migration;GO:0030168//platelet activation;GO:0035556//intracellular signal transduction;GO:0031666//positive regulation of lipopolysaccharide-mediated signaling pathway;GO:2000707//positive regulation of dense core granule biogenesis;GO:0090330//regulation of platelet aggregation;GO:0050796//regulation of insulin secretion;GO:0035408//histone H3-T6 phosphorylation;GO:0002159//desmosome assembly;GO:0070555//response to interleukin-1;GO:0007194//negative regulation of adenylate cyclase activity;GO:0043488//regulation of mRNA stability;GO:0045651//positive regulation of macrophage differentiation;GO:0001938//positive regulation of endothelial cell proliferation;GO:0045766//positive regulation of angiogenesis;GO:0007411//axon guidance;GO:0001525//angiogenesis;GO:0038128//ERBB2 signaling pathway;GO:0006468//protein phosphorylation;GO:0045931//positive regulation of mitotic cell cycle;GO:0034351//negative regulation of glial cell apoptotic process;GO:0010613//positive regulation of cardiac muscle hypertrophy;GO:0007155//cell adhesion;GO:0007190//activation of adenylate cyclase activity;GO:0018105//peptidyl-serine phosphorylation;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0043536//positive regulation of blood vessel endothelial cell migration","K02677//classical protein kinase C alpha type [EC:2.7.11.13]","NP_002728.1//protein kinase C alpha type [Homo sapiens]","2//1"]
[196,6247,5.62,3.51,-0.679099099916366,{"v":4.43768132436627E-9,"d":"4.44E-09"},"*",{"v":5.37e-10,"d":"5.37E-10"},"AHR","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0034753//nuclear aryl hydrocarbon receptor complex;GO:0034752//cytosolic aryl hydrocarbon receptor complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043234//protein complex;GO:0005667//transcription factor complex;GO:0034751//aryl hydrocarbon receptor complex","GO:0001223//transcription coactivator binding;GO:0003677//DNA binding;GO:0070888//E-box binding;GO:0046982//protein heterodimerization activity;GO:0044212//transcription regulatory region DNA binding;GO:0004879//nuclear receptor activity;GO:0046983//protein dimerization activity;GO:0051879//Hsp90 protein binding;GO:0017025//TBP-class protein binding;GO:0004874//aryl hydrocarbon receptor activity;GO:0035326//enhancer binding;GO:0008134//transcription factor binding;GO:0003700//DNA binding transcription factor activity;GO:0001094//TFIID-class transcription factor binding","GO:0010468//regulation of gene expression;GO:0006355//regulation of transcription, DNA-templated;GO:0001568//blood vessel development;GO:0009636//response to toxic substance;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0032922//circadian regulation of gene expression;GO:0045892//negative regulation of transcription, DNA-templated;GO:0030888//regulation of B cell proliferation;GO:0009410//response to xenobiotic stimulus;GO:0006805//xenobiotic metabolic process;GO:0006351//transcription, DNA-templated;GO:0006915//apoptotic process;GO:0006366//transcription from RNA polymerase II promoter;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007049//cell cycle","K09093//aryl hydrocarbon receptor","NP_001612.1//aryl hydrocarbon receptor [Homo sapiens]",4]
[11223,4668,0.32,0.2,-0.678071905112638,0.355984045519787,"*",0.21737,"MST1L","GO:0005615//extracellular space","GO:0004252//serine-type endopeptidase activity","NA","K05460//hepatocyte growth factor","NP_001258662.1//putative macrophage stimulating 1-like protein [Homo sapiens]","1//3"]
[83872,18212,0.08,0.05,-0.678071905112638,0.355911068060681,"*",0.21737,"HMCN1","GO:0070062//extracellular exosome;GO:0032154//cleavage furrow;GO:0005938//cell cortex;GO:0030054//cell junction;GO:0005604//basement membrane","GO:0005509//calcium ion binding","GO:0051301//cell division;GO:0050896//response to stimulus;GO:0007601//visual perception;GO:0007049//cell cycle","K17341//hemicentin","NP_114141.2//hemicentin-1 precursor [Homo sapiens]","2//1"]
[57335,5519,6.64,4.15,-0.678071905112637,{"v":2.48031417988292e-09,"d":"2.48E-09"},"*",{"v":2.91756E-10,"d":"2.92E-10"},"ZNF286A","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_019612967.1//PREDICTED: zinc finger protein 850 isoform X5 [Rhinolophus sinicus]","1//3;2//1"]
[10983,1724,41.19,25.77,-0.676601589008637,{"v":7.27167648780488e-18,"d":"7.27E-18"},"*",{"v":4.10608E-19,"d":"4.11E-19"},"CCNI","NA","NA","GO:0051726//regulation of cell cycle;GO:0007283//spermatogenesis","K10146//cyclin G2;K16939//septin 6/8/11","NP_001335064.1//cyclin-I isoform c [Homo sapiens];BAD93003.1//CCNI protein variant, partial [Homo sapiens];XP_021116662.1//cyclin-I isoform X3 [Heterocephalus glaber];NP_001335063.1//cyclin-I isoform b [Homo sapiens];NP_001335067.1//cyclin-I isoform f [Homo sapiens];NP_001335068.1//cyclin-I isoform g [Homo sapiens];NP_001335066.1//cyclin-I isoform e [Homo sapiens];NP_001335065.1//cyclin-I isoform d [Homo sapiens]","1//3;2//1"]
[221786,2548,2.38,1.49,-0.675649242845782,0.0239991647392438,"*",9.21866E-3,"FAM200A","GO:0005654//nucleoplasm;GO:0016021//integral component of membrane;GO:0005737//cytoplasm","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0003677//DNA binding","NA","K09228//KRAB domain-containing zinc finger protein;K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K02927//large subunit ribosomal protein L40e;K01064//wingless-type MMTV integration site family, member 9","NP_659802.1//protein FAM200A [Homo sapiens]","3//A2MP1"]
[157983,2786,0.75,0.47,-0.674229838818244,0.229640571826869,"*",0.1278736,"C9orf66","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein;K11447//histone demethylase [EC:1.14.11.-]","NP_689782.2//uncharacterized protein C9orf66 [Homo sapiens]","2//1"]
[81624,4768,5.04,3.16,-0.673499175322814,{"v":7.55421633205227E-7,"d":"7.55E-07"},"*",{"v":1.230504E-7,"d":"1.23E-07"},"DIAPH3","GO:0005634//nucleus;GO:0005829//cytosol","GO:0003779//actin binding;GO:0017048//Rho GTPase binding;GO:0045296//cadherin binding","GO:0030036//actin cytoskeleton organization;GO:0007283//spermatogenesis","K05745//diaphanous 3","NP_001245295.1//protein diaphanous homolog 3 isoform c [Homo sapiens];NP_001245298.1//protein diaphanous homolog 3 isoform f [Homo sapiens];EAW52069.1//diaphanous homolog 3 (Drosophila), isoform CRA_a [Homo sapiens];NP_001035982.1//protein diaphanous homolog 3 isoform a [Homo sapiens];NP_001245297.1//protein diaphanous homolog 3 isoform e [Homo sapiens];NP_001245296.1//protein diaphanous homolog 3 isoform d [Homo sapiens]","1//3;3//A2MP1"]
[26271,2143,11.24,7.05,-0.67294687293477,{"v":3.45434422083333e-06,"d":"3.45E-06"},"*",{"v":6.22794e-07,"d":"6.23E-07"},"FBXO5","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005819//spindle;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:1990948//ubiquitin ligase inhibitor activity;GO:0019901//protein kinase binding","GO:0007346//regulation of mitotic cell cycle;GO:0001556//oocyte maturation;GO:0007088//regulation of mitotic nuclear division;GO:0016050//vesicle organization;GO:0007057//spindle assembly involved in female meiosis I;GO:0045835//negative regulation of meiotic nuclear division;GO:1904668//positive regulation of ubiquitin protein ligase activity;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition;GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0051301//cell division;GO:0046785//microtubule polymerization;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle","K10292//F-box protein 5","NP_036309.1//F-box only protein 5 isoform a [Homo sapiens]","4;2//1"]
[7465,3359,8.97,5.63,-0.671973062839032,{"v":1.26170003475269E-7,"d":"1.26E-07"},"*",{"v":1.836392e-08,"d":"1.84E-08"},"WEE1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm","GO:0000287//magnesium ion binding;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity","GO:0000278//mitotic cell cycle;GO:0000226//microtubule cytoskeleton organization;GO:0030010//establishment of cell polarity;GO:0048812//neuron projection morphogenesis;GO:0051301//cell division;GO:0000082//G1/S transition of mitotic cell cycle;GO:0000086//G2/M transition of mitotic cell cycle;GO:0051726//regulation of cell cycle","K06632//wee1-like protein kinase [EC:2.7.11.1]","NP_003381.1//wee1-like protein kinase isoform 1 [Homo sapiens];XP_003254976.1//PREDICTED: wee1-like protein kinase isoform X3 [Nomascus leucogenys]","1//3;3//A2MP1"]
[5332,5425,2.74,1.72,-0.671767328258429,0.000260724020967742,"*",{"v":6.47648e-05,"d":"6.48E-05"},"PLCB4","GO:0005790//smooth endoplasmic reticulum;GO:0030425//dendrite;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005622//intracellular;GO:0014069//postsynaptic density","GO:0004435//phosphatidylinositol phospholipase C activity;GO:0005509//calcium ion binding;GO:0004871//signal transducer activity;GO:0004629//phospholipase C activity","GO:0016042//lipid catabolic process;GO:0043647//inositol phosphate metabolic process;GO:0035556//intracellular signal transduction","K05858//phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]","XP_016792922.1//PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X4 [Pan troglodytes];XP_009435053.2//PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X5 [Pan troglodytes];XP_016792923.1//PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X6 [Pan troglodytes]","1//3;3//A2MP1;2//1"]
[9581,6057,11.11,6.98,-0.67055987517944,{"v":3.72455713868613E-17,"d":"3.72E-17"},"*",{"v":2.23604E-18,"d":"2.24E-18"},"PREPL","GO:0005856//cytoskeleton;GO:0005794//Golgi apparatus;GO:0005829//cytosol","GO:0004252//serine-type endopeptidase activity;GO:0070008//serine-type exopeptidase activity","GO:2000300//regulation of synaptic vesicle exocytosis","K14210//solute carrier family 3 (neutral and basic amino acid transporter), member 1","NP_001035844.1//prolyl endopeptidase-like isoform 2 [Homo sapiens];NP_006027.2//prolyl endopeptidase-like isoform 1 [Homo sapiens];NP_001035845.1//prolyl endopeptidase-like isoform 3 [Homo sapiens]","4;1//3;2//1"]
[405,4875,8.91,5.6,-0.669998604576956,{"v":6.4731296464582e-11,"d":"6.47E-11"},"*",{"v":6.34994e-12,"d":"6.35E-12"},"ARNT","GO:0090575//RNA polymerase II transcription factor complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription factor complex;GO:0016604//nuclear body;GO:0005737//cytoplasm","GO:0003713//transcription coactivator activity;GO:0046982//protein heterodimerization activity;GO:0035326//enhancer binding;GO:0004874//aryl hydrocarbon receptor activity;GO:0008134//transcription factor binding;GO:0003700//DNA binding transcription factor activity;GO:0017162//aryl hydrocarbon receptor binding;GO:0046983//protein dimerization activity","GO:0046886//positive regulation of hormone biosynthetic process;GO:0010575//positive regulation of vascular endothelial growth factor production;GO:0033235//positive regulation of protein sumoylation;GO:0042789//mRNA transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0001892//embryonic placenta development;GO:0045821//positive regulation of glycolytic process;GO:0043619//regulation of transcription from RNA polymerase II promoter in response to oxidative stress;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0001938//positive regulation of endothelial cell proliferation;GO:0030154//cell differentiation;GO:0030949//positive regulation of vascular endothelial growth factor receptor signaling pathway;GO:0006805//xenobiotic metabolic process;GO:0006351//transcription, DNA-templated;GO:0001666//response to hypoxia;GO:0045648//positive regulation of erythrocyte differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter","K09097//aryl hydrocarbon receptor nuclear translocator","XP_008017478.1//PREDICTED: aryl hydrocarbon receptor nuclear translocator isoform X4 [Chlorocebus sabaeus];XP_008017477.1//PREDICTED: aryl hydrocarbon receptor nuclear translocator isoform X3 [Chlorocebus sabaeus];CAD38953.1//hypothetical protein, partial [Homo sapiens];NP_001337155.1//aryl hydrocarbon receptor nuclear translocator isoform 9 [Homo sapiens];NP_001337154.1//aryl hydrocarbon receptor nuclear translocator isoform 8 [Homo sapiens];XP_008017475.1//PREDICTED: aryl hydrocarbon receptor nuclear translocator isoform X1 [Chlorocebus sabaeus];XP_011793190.1//PREDICTED: aryl hydrocarbon receptor nuclear translocator isoform X2 [Colobus angolensis palliatus]","1//3;3//A2MP1;2//1"]
[130507,7969,3.21,2.02,-0.668218004370508,{"v":8.94936962833206e-07,"d":"8.95E-07"},"*",{"v":1.471206e-07,"d":"1.47E-07"},"UBR3","GO:0000151//ubiquitin ligase complex;GO:0016021//integral component of membrane;GO:0005737//cytoplasm","GO:0061630//ubiquitin protein ligase activity;GO:0008270//zinc ion binding;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity","GO:0007608//sensory perception of smell;GO:0071596//ubiquitin-dependent protein catabolic process via the N-end rule pathway;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0001967//suckling behavior;GO:0042048//olfactory behavior;GO:0009790//embryo development;GO:0001701//in utero embryonic development","K11978//E3 ubiquitin-protein ligase UBR3 [EC:2.3.2.27]","NP_742067.3//E3 ubiquitin-protein ligase UBR3 [Homo sapiens]","3//A2MP1"]
[253512,3691,2.92,1.84,-0.666262602823005,0.00342475003648026,"*",1.069618E-3,"SLC25A30","GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0005739//mitochondrion","GO:0022857//transmembrane transporter activity","GO:0006839//mitochondrial transport","K15106//solute carrier family 25 (mitochondrial carrier), member 14/30","NP_001010875.1//kidney mitochondrial carrier protein 1 isoform 1 [Homo sapiens];XP_011919750.1//PREDICTED: kidney mitochondrial carrier protein 1 isoform X1 [Cercocebus atys];NP_001273735.1//kidney mitochondrial carrier protein 1 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[9923,8521,4.14,2.61,-0.665580960929441,{"v":9.4248021490545e-10,"d":"9.42E-10"},"*",{"v":1.060836e-10,"d":"1.06E-10"},"ZBTB40","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003676//nucleic acid binding","GO:0030282//bone mineralization;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006974//cellular response to DNA damage stimulus","K10512//zinc finger and BTB domain-containing protein 40","NP_055685.3//zinc finger and BTB domain-containing protein 40 isoform a [Homo sapiens];NP_001317327.1//zinc finger and BTB domain-containing protein 40 isoform b [Homo sapiens]","1//3;3//A2MP1"]
[64375,4894,1.76,1.11,-0.665015752287191,0.00641906160954365,"*",0.00212214,"IKZF4","NA","GO:0003676//nucleic acid binding","NA","K09220//IKAROS family zinc finger protein","XP_020947441.1//zinc finger protein Eos isoform X1 [Sus scrofa];XP_009246156.1//PREDICTED: zinc finger protein Eos isoform X1 [Pongo abelii];XP_008976879.1//PREDICTED: zinc finger protein Eos isoform X5 [Pan paniscus]","1//3;3//A2MP1"]
[57462,6452,5.18,3.27,-0.663661462188471,{"v":1.73112128053435e-08,"d":"1.73E-08"},"*",{"v":2.27146e-09,"d":"2.27E-09"},"MYORG","GO:0031965//nuclear membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds","GO:0051897//positive regulation of protein kinase B signaling;GO:0005975//carbohydrate metabolic process;GO:0048741//skeletal muscle fiber development;GO:0043568//positive regulation of insulin-like growth factor receptor signaling pathway","K10955//mucin-2;K01187//alpha-glucosidase [EC:3.2.1.20];K05546//alpha 1,3-glucosidase [EC:3.2.1.84];K12316//lysosomal alpha-glucosidase [EC:3.2.1.20]","NP_065753.2//uncharacterized family 31 glucosidase KIAA1161 [Homo sapiens]",4]
[4146,3830,0.19,0.12,-0.662965012722429,0.612300480912828,"*",0.456868,"MATN1","GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix","GO:0005201//extracellular matrix structural constituent;GO:0005509//calcium ion binding","GO:0003429//growth plate cartilage chondrocyte morphogenesis;GO:0030500//regulation of bone mineralization;GO:0030198//extracellular matrix organization;GO:0006461//protein complex assembly","K19467//matrilin-3","NP_002370.1//cartilage matrix protein precursor [Homo sapiens]","3//A2MP1"]
[9748,7770,7.83,4.95,-0.661583782324069,{"v":1.65841403570191e-14,"d":"1.66E-14"},"*",{"v":1.198078e-15,"d":"1.20E-15"},"SLK","GO:0070062//extracellular exosome;GO:0031252//cell leading edge;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm","GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0045296//cadherin binding","GO:0023014//signal transduction by protein phosphorylation;GO:0007346//regulation of mitotic cell cycle;GO:0032147//activation of protein kinase activity;GO:0046777//protein autophosphorylation;GO:0006915//apoptotic process;GO:0051893//regulation of focal adhesion assembly;GO:0030334//regulation of cell migration;GO:0031098//stress-activated protein kinase signaling cascade;GO:0042981//regulation of apoptotic process;GO:0031122//cytoplasmic microtubule organization","K08836//STE20-like kinase [EC:2.7.11.1]","NP_055535.2//STE20-like serine/threonine-protein kinase isoform 1 [Homo sapiens];NP_001291672.1//STE20-like serine/threonine-protein kinase isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[92999,5524,3.46,2.19,-0.659841168035551,{"v":3.61944100204141e-05,"d":"3.62E-05"},"*",{"v":7.76954e-06,"d":"7.77E-06"},"ZBTB47","NA","NA","NA","K10518//zinc finger and BTB domain-containing protein 47","XP_008959737.2//PREDICTED: zinc finger and BTB domain-containing protein 47 [Pan paniscus]","3//A2MP1"]
[5774,6753,5.37,3.4,-0.659387341847711,{"v":7.10582134274194e-09,"d":"7.11E-09"},"*",{"v":8.82556e-10,"d":"8.83E-10"},"PTPN3","GO:0005856//cytoskeleton;GO:0009898//cytoplasmic side of plasma membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0001784//phosphotyrosine residue binding;GO:0017080//sodium channel regulator activity;GO:0008092//cytoskeletal protein binding;GO:0004725//protein tyrosine phosphatase activity;GO:0051117//ATPase binding","GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:2000649//regulation of sodium ion transmembrane transporter activity;GO:0045930//negative regulation of mitotic cell cycle;GO:0097421//liver regeneration;GO:0006470//protein dephosphorylation;GO:0051045//negative regulation of membrane protein ectodomain proteolysis;GO:0098902//regulation of membrane depolarization during action potential","K18027//tyrosine-protein phosphatase non-receptor type 3 [EC:3.1.3.48]","XP_007966658.1//PREDICTED: tyrosine-protein phosphatase non-receptor type 3 isoform X1 [Chlorocebus sabaeus];XP_011517190.1//PREDICTED: tyrosine-protein phosphatase non-receptor type 3 isoform X1 [Homo sapiens];XP_007966660.1//PREDICTED: tyrosine-protein phosphatase non-receptor type 3 isoform X2 [Chlorocebus sabaeus];XP_016870445.1//PREDICTED: tyrosine-protein phosphatase non-receptor type 3 isoform X7 [Homo sapiens];XP_006717265.1//PREDICTED: tyrosine-protein phosphatase non-receptor type 3 isoform X5 [Homo sapiens]","1//3;3//A2MP1"]
[647135,6810,4.72,2.99,-0.658641375163736,{"v":5.8722250415364e-08,"d":"5.87E-08"},"*",{"v":8.23082e-09,"d":"8.23E-09"},"SRGAP2B","GO:0005737//cytoplasm","GO:0048365//Rac GTPase binding;GO:0005096//GTPase activator activity","GO:0007399//nervous system development;GO:0007165//signal transduction;GO:0030336//negative regulation of cell migration","K07526//SLIT-ROBO Rho GTPase activating protein","NP_001258799.2//SLIT-ROBO Rho GTPase-activating protein 2B isoform 1 [Homo sapiens];XP_016857574.1//PREDICTED: SLIT-ROBO Rho GTPase-activating protein 2B isoform X1 [Homo sapiens]","1//3;2//1"]
[4082,4322,12.23,7.75,-0.658156188365787,{"v":1.77215532560528E-12,"d":"1.77E-12"},"*",{"v":1.512112E-13,"d":"1.51E-13"},"MARCKS","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005925//focal adhesion;GO:0005938//cell cortex;GO:0005813//centrosome;GO:0042585//germinal vesicle;GO:0015629//actin cytoskeleton;GO:0032432//actin filament bundle;GO:0005886//plasma membrane","GO:0051015//actin filament binding;GO:0005080//protein kinase C binding;GO:0016301//kinase activity;GO:0042802//identical protein binding;GO:0005516//calmodulin binding","GO:0051017//actin filament bundle assembly;GO:0051764//actin crosslink formation;GO:0051260//protein homooligomerization;GO:0050796//regulation of insulin secretion","K12561//myristoylated alanine-rich C-kinase substrate","NP_002347.5//myristoylated alanine-rich C-kinase substrate [Homo sapiens]",6]
[200424,11405,3.17,2.01,-0.657287338960479,{"v":9.06075752011923e-09,"d":"9.06E-09"},"*",{"v":1.141812E-9,"d":"1.14E-09"},"TET3","GO:0001940//male pronucleus;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0070579//methylcytosine dioxygenase activity","GO:0006493//protein O-linked glycosylation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0080182//histone H3-K4 trimethylation;GO:0080111//DNA demethylation;GO:0044727//DNA demethylation of male pronucleus","K13097//methylcytosine dioxygenase [EC:1.14.11.-]","NP_001274420.1//methylcytosine dioxygenase TET3 [Homo sapiens]","1//3"]
[55612,5167,6.99,4.44,-0.65473277902533,{"v":8.20030550898204e-09,"d":"8.20E-09"},"*",{"v":1.02876e-09,"d":"1.03E-09"},"FERMT1","GO:0005925//focal adhesion;GO:0005829//cytosol;GO:0030054//cell junction;GO:0032587//ruffle membrane;GO:0031941//filamentous actin","NA","GO:2001203//positive regulation of transforming growth factor-beta secretion;GO:0071711//basement membrane organization;GO:0001954//positive regulation of cell-matrix adhesion;GO:0043616//keratinocyte proliferation;GO:0010629//negative regulation of gene expression;GO:0090162//establishment of epithelial cell polarity;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0007155//cell adhesion;GO:2000647//negative regulation of stem cell proliferation;GO:0051886//negative regulation of timing of anagen;GO:0035414//negative regulation of catenin import into nucleus;GO:0051546//keratinocyte migration;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0033630//positive regulation of cell adhesion mediated by integrin","K17082//kindlin 1","NP_060141.3//fermitin family homolog 1 [Homo sapiens]",4]
[196415,1516,1.59,1.01,-0.654671472532561,0.209279601485091,"*",0.1129198,"C12orf77","NA","NA","NA","K01064//wingless-type MMTV integration site family, member 9","NP_001094809.2//putative uncharacterized protein C12orf77 [Homo sapiens]","2//1"]
[5922,5648,2.2,1.4,-0.652076696579693,1.3582356564952E-3,"*",0.000390108,"RASA2","GO:0005829//cytosol;GO:0005622//intracellular;GO:0031235//intrinsic component of the cytoplasmic side of the plasma membrane;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm","GO:0046872//metal ion binding;GO:0005096//GTPase activator activity","GO:0046580//negative regulation of Ras protein signal transduction;GO:0000165//MAPK cascade;GO:0007165//signal transduction;GO:0035556//intracellular signal transduction","K08053//Ras GTPase-activating protein 2","NP_001290174.1//ras GTPase-activating protein 2 isoform 2 [Homo sapiens];NP_001290175.1//ras GTPase-activating protein 2 isoform 1 [Homo sapiens];NP_006497.2//ras GTPase-activating protein 2 isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[339883,1836,0.22,0.14,-0.652076696579693,0.63128138316018,"*",0.50972,"C3orf35","GO:0016021//integral component of membrane","NA","NA","NA","XP_003945335.1//PREDICTED: LOW QUALITY PROTEIN: AP20 region protein 1 [Saimiri boliviensis boliviensis];XP_017363931.1//PREDICTED: LOW QUALITY PROTEIN: AP20 region protein 1 [Cebus capucinus imitator];NP_848029.2//AP20 region protein 1 isoform B [Homo sapiens]","1//3;2//1"]
[2646,2197,0.11,0.07,-0.652076696579693,0.781374807266534,"*",0.689316,"GCKR","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005737//cytoplasm","GO:0030246//carbohydrate binding;GO:0019904//protein domain specific binding;GO:0097367//carbohydrate derivative binding;GO:0016301//kinase activity;GO:0004857//enzyme inhibitor activity;GO:0019899//enzyme binding;GO:0070095//fructose-6-phosphate binding","GO:0000060//protein import into nucleus, translocation;GO:0009750//response to fructose;GO:0006110//regulation of glycolytic process;GO:1901135//carbohydrate derivative metabolic process;GO:0001678//cellular glucose homeostasis;GO:0070328//triglyceride homeostasis;GO:0005975//carbohydrate metabolic process;GO:0033132//negative regulation of glucokinase activity;GO:0033133//positive regulation of glucokinase activity;GO:0046415//urate metabolic process","NA","NP_001477.2//glucokinase regulatory protein [Homo sapiens]","3//A2MP1"]
[4249,8163,5.76,3.67,-0.6502887485991,{"v":3.96815041045752e-11,"d":"3.97E-11"},"*",{"v":3.80072e-12,"d":"3.80E-12"},"MGAT5","GO:0070062//extracellular exosome;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0030144//alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity","GO:0006487//protein N-linked glycosylation","K00744//alpha-1,3(6)-mannosylglycoprotein beta-1,6-N-acetyl-glucosaminyltransferase [EC:2.4.1.155]","NP_002401.1//alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A [Homo sapiens]",4]
[23118,4175,15.09,9.63,-0.647985102683224,{"v":3.20138387837838E-14,"d":"3.20E-14"},"*",{"v":2.37288E-15,"d":"2.37E-15"},"TAB2","GO:0010008//endosome membrane;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0070530//K63-linked polyubiquitin modification-dependent protein binding;GO:0046872//metal ion binding;GO:0016301//kinase activity","GO:0070423//nucleotide-binding oligomerization domain containing signaling pathway;GO:0000187//activation of MAPK activity;GO:0050852//T cell receptor signaling pathway;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0007507//heart development;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0007254//JNK cascade;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0010507//negative regulation of autophagy;GO:0045860//positive regulation of protein kinase activity;GO:0002755//MyD88-dependent toll-like receptor signaling pathway","K04404//TAK1-binding protein 2","NP_001278964.1//TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform b [Homo sapiens];NP_055908.1//TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform a [Homo sapiens]","2//1;5"]
[284371,3760,1.41,0.9,-0.647698256069119,0.0535548753037623,"*",0.0229018,"ZNF841","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","XP_016882144.1//PREDICTED: zinc finger protein 841 isoform X3 [Homo sapiens];XP_016789777.1//PREDICTED: zinc finger protein 841 isoform X2 [Pan troglodytes]","1//3"]
[6785,3085,0.72,0.46,-0.646363045385299,0.256205093879348,"*",0.1456972,"ELOVL4","GO:0005783//endoplasmic reticulum;GO:0030176//integral component of endoplasmic reticulum membrane","GO:0009922//fatty acid elongase activity;GO:0008020//G-protein coupled photoreceptor activity;GO:0102336//3-oxo-arachidoyl-CoA synthase activity;GO:0102756//very-long-chain 3-ketoacyl-CoA synthase activity;GO:0102337//3-oxo-cerotoyl-CoA synthase activity;GO:0102338//3-oxo-lignoceronyl-CoA synthase activity","GO:0019367//fatty acid elongation, saturated fatty acid;GO:0006636//unsaturated fatty acid biosynthetic process;GO:0034626//fatty acid elongation, polyunsaturated fatty acid;GO:0030148//sphingolipid biosynthetic process;GO:0035338//long-chain fatty-acyl-CoA biosynthetic process;GO:0006633//fatty acid biosynthetic process;GO:0042761//very long-chain fatty acid biosynthetic process;GO:0034625//fatty acid elongation, monounsaturated fatty acid","K10249//elongation of very long chain fatty acids protein 4 [EC:2.3.1.199]","NP_073563.1//elongation of very long chain fatty acids protein 4 [Homo sapiens]","3//A2MP1"]
[245972,2370,0.86,0.55,-0.644905041177438,0.286129816718801,"*",0.1660642,"ATP6V0D2","GO:0033179//proton-transporting V-type ATPase, V0 domain;GO:0016020//membrane;GO:0005765//lysosomal membrane;GO:0070062//extracellular exosome;GO:0010008//endosome membrane;GO:0016324//apical plasma membrane;GO:0030670//phagocytic vesicle membrane;GO:0016471//vacuolar proton-transporting V-type ATPase complex;GO:0005769//early endosome","GO:0015078//hydrogen ion transmembrane transporter activity;GO:0008553//hydrogen-exporting ATPase activity, phosphorylative mechanism;GO:0046961//proton-transporting ATPase activity, rotational mechanism","GO:0016241//regulation of macroautophagy;GO:0008286//insulin receptor signaling pathway;GO:0034220//ion transmembrane transport;GO:0090383//phagosome acidification;GO:0007034//vacuolar transport;GO:0007035//vacuolar acidification;GO:0015991//ATP hydrolysis coupled proton transport;GO:0033572//transferrin transport","K02146//V-type H+-transporting ATPase subunit d","CAH92343.1//hypothetical protein [Pongo abelii]","1//3"]
[9724,5537,3.08,1.97,-0.644734721238525,0.00014718977883959,"*",{"v":3.50974E-5,"d":"3.51E-05"},"UTP14C","GO:0032040//small-subunit processome;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0019013//viral nucleocapsid","NA","GO:0030154//cell differentiation;GO:0007275//multicellular organism development;GO:0051321//meiotic cell cycle;GO:0006364//rRNA processing;GO:0007283//spermatogenesis;GO:0030490//maturation of SSU-rRNA","K14567//U3 small nucleolar RNA-associated protein 14","NP_067677.4//U3 small nucleolar RNA-associated protein 14 homolog C [Homo sapiens]",5]
[5340,1200,0.75,0.48,-0.643856189774725,0.156398330602763,"*",0.080079,"PLG","GO:0044218//other organism cell membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0072562//blood microparticle;GO:0031232//extrinsic component of external side of plasma membrane;GO:0031093//platelet alpha granule lumen;GO:0009986//cell surface;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0004252//serine-type endopeptidase activity;GO:0004175//endopeptidase activity;GO:0034185//apolipoprotein binding;GO:0005102//receptor binding;GO:1904854//proteasome core complex binding;GO:0051087//chaperone binding;GO:0008236//serine-type peptidase activity;GO:1990405//protein antigen binding;GO:0019904//protein domain specific binding;GO:0019900//kinase binding;GO:0019899//enzyme binding","GO:0048771//tissue remodeling;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0007596//blood coagulation;GO:0042246//tissue regeneration;GO:0051918//negative regulation of fibrinolysis;GO:0044267//cellular protein metabolic process;GO:0002576//platelet degranulation;GO:0045445//myoblast differentiation;GO:0008285//negative regulation of cell proliferation;GO:0042730//fibrinolysis;GO:0071674//mononuclear cell migration;GO:0060716//labyrinthine layer blood vessel development;GO:0060707//trophoblast giant cell differentiation;GO:0052213//interaction with symbiont via secreted substance involved in symbiotic interaction;GO:0046716//muscle cell cellular homeostasis;GO:0022617//extracellular matrix disassembly;GO:0006508//proteolysis;GO:0051702//interaction with symbiont;GO:0051919//positive regulation of fibrinolysis;GO:0010812//negative regulation of cell-substrate adhesion;GO:2000048//negative regulation of cell-cell adhesion mediated by cadherin;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0052182//modification by host of symbiont morphology or physiology via secreted substance","K01315//plasminogen [EC:3.4.21.7]","AAA36451.1//plasminogen [Homo sapiens];NP_000292.1//plasminogen isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[389177,1902,22.81,14.62,-0.6417231353597,{"v":6.44561791363636e-10,"d":"6.45E-10"},"*",{"v":7.10172e-11,"d":"7.10E-11"},"TMEM212","NA","NA","NA","K22196//transmembrane protein 212","KRX57831.1//LINE-1 reverse transcriptase -like protein [Trichinella sp. T6]","1//3"]
[23245,3516,16.96,10.88,-0.64045761331286,{"v":1.79798394756703E-16,"d":"1.80E-16"},"*",{"v":1.133448E-17,"d":"1.13E-17"},"ASTN2","GO:0060187//cell pole;GO:0005770//late endosome;GO:0005938//cell cortex;GO:0030136//clathrin-coated vesicle;GO:0016021//integral component of membrane;GO:0005769//early endosome;GO:0043204//perikaryon","GO:0005509//calcium ion binding;GO:0043533//inositol 1,3,4,5 tetrakisphosphate binding","GO:2000009//negative regulation of protein localization to cell surface;GO:0048105//establishment of body hair planar orientation;GO:0015031//protein transport","K19475//WAS/WASL-interacting protein;K10408//dynein heavy chain, axonemal;K04534//guanine nucleotide-binding protein G(o) subunit alpha;K19901//disabled homolog 2-interacting protein;K05030//calcium-activated chloride channel regulator 3/4;K14480//apolipoprotein L","NP_937829.3//astrotactin-2 isoform b [Homo sapiens];XP_011748720.1//PREDICTED: astrotactin-2 isoform X2 [Macaca nemestrina];XP_008697065.1//PREDICTED: astrotactin-2 isoform X3 [Ursus maritimus];XP_008697064.1//PREDICTED: astrotactin-2 isoform X2 [Ursus maritimus];KRX57831.1//LINE-1 reverse transcriptase -like protein [Trichinella sp. T6];XP_007966444.1//PREDICTED: astrotactin-2 isoform X4 [Chlorocebus sabaeus]","4;1//3;3//A2MP1;2//1"]
[140883,5765,2.01,1.29,-0.639824435755674,0.00268058402708248,"*",0.000817902,"ZNF280B","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","EAW59515.1//suppressor of hairy wing homolog 2 (Drosophila), isoform CRA_a, partial [Homo sapiens]","3//A2MP1"]
[84248,3682,8.9,5.72,-0.637790189075371,{"v":1.0560224492388E-7,"d":"1.06E-07"},"*",{"v":1.519842E-8,"d":"1.52E-08"},"FYTTD1","GO:0005654//nucleoplasm;GO:0016607//nuclear speck","GO:0003723//RNA binding;GO:0003729//mRNA binding","GO:0006406//mRNA export from nucleus","K15696//RING finger protein 113B;K17985//activating molecule in BECN1-regulated autophagy protein 1;K20858//calcium uniporter protein, mitochondrial;K01064//wingless-type MMTV integration site family, member 9","XP_002759822.2//PREDICTED: UAP56-interacting factor isoform X1 [Callithrix jacchus];NP_001011537.2//UAP56-interacting factor isoform 2 [Homo sapiens]","6;2//1"]
[285025,7421,0.28,0.18,-0.637429920615292,0.363629213670013,"*",0.224474,"CCDC141","GO:0005815//microtubule organizing center;GO:0005737//cytoplasm","NA","NA","K12567//titin [EC:2.7.11.1]","NP_775919.3//coiled-coil domain-containing protein 141 isoform 1 [Homo sapiens];NP_001303674.1//coiled-coil domain-containing protein 141 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[10658,5800,17.51,11.26,-0.636972256353328,{"v":1.41763610574713E-23,"d":"1.42E-23"},"*",{"v":5.40466e-25,"d":"5.40E-25"},"CELF1","GO:0016020//membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0030529//intracellular ribonucleoprotein complex;GO:0005737//cytoplasm","GO:0000900//translation repressor activity, nucleic acid binding;GO:0003723//RNA binding;GO:0036002//pre-mRNA binding;GO:0003729//mRNA binding;GO:0042835//BRE binding","GO:0043484//regulation of RNA splicing;GO:0006397//mRNA processing;GO:0016246//RNA interference;GO:0006376//mRNA splice site selection;GO:0007281//germ cell development;GO:0009790//embryo development","K13207//CUG-BP- and ETR3-like factor","EDL27515.1//CUG triplet repeat, RNA binding protein 1, isoform CRA_d, partial [Mus musculus];NP_001166110.1//CUGBP Elav-like family member 1 isoform 4 [Homo sapiens];XP_017384673.1//PREDICTED: CUGBP Elav-like family member 1 isoform X3 [Cebus capucinus imitator];XP_007113017.1//PREDICTED: CUGBP Elav-like family member 1 isoform X4 [Physeter catodon];XP_007113014.1//PREDICTED: CUGBP Elav-like family member 1 isoform X1 [Physeter catodon];XP_020034686.1//CUGBP Elav-like family member 1 isoform X2 [Castor canadensis]","1//3;3//A2MP1;2//1"]
[160287,1990,0.73,0.47,-0.63523570720238,0.335819082069395,"*",0.202366,"LDHAL6A","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0004459//L-lactate dehydrogenase activity","GO:0019752//carboxylic acid metabolic process;GO:0005975//carbohydrate metabolic process","K00016//L-lactate dehydrogenase [EC:1.1.1.27]","XP_012509723.1//PREDICTED: LOW QUALITY PROTEIN: L-lactate dehydrogenase A-like 6A [Propithecus coquereli];XP_009458321.2//PREDICTED: L-lactate dehydrogenase A-like 6A [Pan troglodytes]","1//3;4"]
[3216,1686,9.28,5.98,-0.633979320929467,0.000445974880480769,"*",1.161422E-4,"HOXB6","NA","NA","NA","K09306//homeobox protein HoxA/B/C6","XP_008951104.1//PREDICTED: homeobox protein Hox-B6 isoform X1 [Pan paniscus]",4]
[201299,964,2.9,1.87,-0.633014630127298,0.252138585924207,"*",0.1428638,"RDM1","GO:0016605//PML body;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0015030//Cajal body","GO:0003723//RNA binding;GO:0003677//DNA binding","GO:0006281//DNA repair;GO:0006310//DNA recombination","K10874//RAD52 motif-containing protein 1","NP_001156592.1//RAD52 motif-containing protein 1 isoform 3 [Homo sapiens];NP_001156593.1//RAD52 motif-containing protein 1 isoform 4 [Homo sapiens];NP_001156596.1//RAD52 motif-containing protein 1 isoform 6 [Homo sapiens];NP_001317123.1//RAD52 motif-containing protein 1 isoform 9 [Homo sapiens];NP_001030008.1//RAD52 motif-containing protein 1 isoform 2 [Homo sapiens];NP_001156594.1//RAD52 motif-containing protein 1 isoform 5 [Homo sapiens];NP_663629.1//RAD52 motif-containing protein 1 isoform 1 [Homo sapiens];NP_001156597.1//RAD52 motif-containing protein 1 isoform 7 [Homo sapiens];NP_001156602.1//RAD52 motif-containing protein 1 isoform 8 [Homo sapiens]","1//3;3//A2MP1"]
[80817,4488,2.03,1.31,-0.631912915647726,0.0126683794969217,"*",4.50856E-3,"CEP44","GO:0000922//spindle pole;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0030496//midbody","NA","NA","K16761//centrosomal protein CEP44","NP_001035247.1//centrosomal protein of 44 kDa isoform a [Homo sapiens];NP_001138786.1//centrosomal protein of 44 kDa isoform b [Homo sapiens]","1//3;2//1"]
[26996,2021,1.47,0.95,-0.629816736505417,0.188229898543517,"*",0.0995118,"GPR160","GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0043235//receptor complex","GO:0004930//G-protein coupled receptor activity","NA","K08438//G protein-coupled receptor 160","NP_055188.1//probable G-protein coupled receptor 160 [Homo sapiens]","2//1"]
[90649,3897,1.16,0.75,-0.629162304631691,0.0844650009920088,"*",0.0383778,"ZNF486","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_009192262.2//LOW QUALITY PROTEIN: putative zinc finger protein 66 [Papio anubis]","3//A2MP1"]
[1840,3317,0.34,0.22,-0.628031222613042,0.458957618181818,"*",0.309726,"DTX1","GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0003713//transcription coactivator activity;GO:0008270//zinc ion binding;GO:0031625//ubiquitin protein ligase binding;GO:0005112//Notch binding;GO:0016740//transferase activity;GO:0017124//SH3 domain binding","GO:0008593//regulation of Notch signaling pathway;GO:0010001//glial cell differentiation;GO:0016567//protein ubiquitination;GO:0006351//transcription, DNA-templated;GO:0007166//cell surface receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0045665//negative regulation of neuron differentiation;GO:1990830//cellular response to leukemia inhibitory factor;GO:0045581//negative regulation of T cell differentiation;GO:0007219//Notch signaling pathway","K06058//deltex [EC:2.3.2.27]","NP_004407.2//E3 ubiquitin-protein ligase DTX1 [Homo sapiens]","2//1"]
[151011,3683,15.01,9.72,-0.626895758014908,{"v":6.94961157692308e-19,"d":"6.95E-19"},"*",{"v":3.61968e-20,"d":"3.62E-20"},"2019-09-10","GO:0005856//cytoskeleton;GO:0005737//cytoplasm","GO:0005525//GTP binding","GO:0051301//cell division;GO:0007049//cell cycle","K16940//septin 10","AAH50345.2//SEPT10 protein [Homo sapiens];NP_001039641.1//septin-10 [Bos taurus];XP_012578710.1//PREDICTED: LOW QUALITY PROTEIN: septin-10 [Condylura cristata];XP_005415300.2//PREDICTED: septin-10 isoform X1 [Chinchilla lanigera];EPQ19193.1//Septin-10 [Myotis brandtii];XP_011509003.1//PREDICTED: septin-10 isoform X6 [Homo sapiens];NP_001308435.1//septin-10 isoform 12 [Homo sapiens];XP_011509005.1//PREDICTED: septin-10 isoform X1 [Homo sapiens];XP_019682488.1//PREDICTED: septin-10 isoform X1 [Felis catus];XP_006215508.2//PREDICTED: septin-10 [Vicugna pacos];XP_011509004.1//PREDICTED: septin-10 isoform X7 [Homo sapiens];NP_001308440.1//septin-10 isoform 17 [Homo sapiens];NP_001308431.1//septin-10 isoform 8 [Homo sapiens];NP_001308432.1//septin-10 isoform 9 [Homo sapiens];NP_001308439.1//septin-10 isoform 16 [Homo sapiens]","4;1//3;3//A2MP1"]
[5570,2012,0.88,0.57,-0.626541604472556,0.318052750173156,"*",0.1897286,"PKIB","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0004862//cAMP-dependent protein kinase inhibitor activity","GO:1904355//positive regulation of telomere capping;GO:2000480//negative regulation of cAMP-dependent protein kinase activity;GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0051973//positive regulation of telomerase activity","K09228//KRAB domain-containing zinc finger protein;K15985//cAMP-dependent protein kinase inhibitor alpha","XP_008005377.1//PREDICTED: cAMP-dependent protein kinase inhibitor beta isoform X2 [Chlorocebus sabaeus];XP_016811732.1//PREDICTED: cAMP-dependent protein kinase inhibitor beta isoform X1 [Pan troglodytes];EAW48170.1//protein kinase (cAMP-dependent, catalytic) inhibitor beta, isoform CRA_c, partial [Homo sapiens]","1//3;2//1;5"]
[2180,3781,5.97,3.87,-0.625397365120395,{"v":1.94195746236559E-5,"d":"1.94E-05"},"*",{"v":3.9571e-06,"d":"3.96E-06"},"ACSL1","GO:0016021//integral component of membrane;GO:0005739//mitochondrion","GO:0004467//long-chain fatty acid-CoA ligase activity;GO:0003824//catalytic activity","GO:0033211//adiponectin-activated signaling pathway;GO:0008152//metabolic process;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0044539//long-chain fatty acid import;GO:0008610//lipid biosynthetic process","K01897//long-chain acyl-CoA synthetase [EC:6.2.1.3]","XP_007998596.1//PREDICTED: long-chain-fatty-acid--CoA ligase 1 isoform X2 [Chlorocebus sabaeus];XP_021567574.1//long-chain-fatty-acid--CoA ligase 1 isoform X2 [Carlito syrichta]","1//3;3//A2MP1"]
[23142,4284,6.32,4.1,-0.624300648671657,{"v":2.2362459e-06,"d":"2.24E-06"},"*",{"v":3.9198e-07,"d":"3.92E-07"},"DCUN1D4","GO:0005634//nucleus;GO:0000151//ubiquitin ligase complex","GO:0032182//ubiquitin-like protein binding;GO:0097602//cullin family protein binding;GO:0031624//ubiquitin conjugating enzyme binding","GO:0045116//protein neddylation;GO:0051443//positive regulation of ubiquitin-protein transferase activity","K17824//DCN1-like protein 4/5","NP_001274684.1//DCN1-like protein 4 isoform 3 [Homo sapiens];XP_011928981.1//PREDICTED: DCN1-like protein 4 isoform X4 [Cercocebus atys];XP_012416428.1//PREDICTED: LOW QUALITY PROTEIN: DCN1-like protein 4 [Odobenus rosmarus divergens]","1//3;3//A2MP1;2//1"]
[8567,5831,10.57,6.86,-0.623694895209871,{"v":4.25049238051044e-13,"d":"4.25E-13"},"*",{"v":3.44052e-14,"d":"3.44E-14"},"MADD","GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0016301//kinase activity;GO:0005123//death receptor binding;GO:0030295//protein kinase activator activity;GO:0017112//Rab guanyl-nucleotide exchange factor activity","GO:0032483//regulation of Rab protein signal transduction;GO:0000187//activation of MAPK activity;GO:0007166//cell surface receptor signaling pathway;GO:0010803//regulation of tumor necrosis factor-mediated signaling pathway;GO:0061024//membrane organization;GO:2001236//regulation of extrinsic apoptotic signaling pathway;GO:1902041//regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0097194//execution phase of apoptosis;GO:0051726//regulation of cell cycle;GO:0042981//regulation of apoptotic process","K18061//myotubularin-related protein 5/13;K20163//DENN domain-containing protein 4","NP_569830.2//MAP kinase-activating death domain protein isoform f [Homo sapiens];NP_003673.3//MAP kinase-activating death domain protein isoform d [Homo sapiens];NP_001129415.1//MAP kinase-activating death domain protein isoform i [Homo sapiens];NP_001129416.1//MAP kinase-activating death domain protein isoform j [Homo sapiens];NP_569831.1//MAP kinase-activating death domain protein isoform g [Homo sapiens];NP_569829.2//MAP kinase-activating death domain protein isoform e [Homo sapiens];NP_569826.2//MAP kinase-activating death domain protein isoform a [Homo sapiens];NP_569828.2//MAP kinase-activating death domain protein isoform c [Homo sapiens];NP_569832.2//MAP kinase-activating death domain protein isoform h [Homo sapiens];NP_569827.2//MAP kinase-activating death domain protein isoform b [Homo sapiens]","1//3;3//A2MP1;2//1"]
[8897,9008,2.91,1.89,-0.622632918687211,{"v":2.7275999280677e-06,"d":"2.73E-06"},"*",{"v":4.84254e-07,"d":"4.84E-07"},"MTMR3","GO:0016020//membrane;GO:0019898//extrinsic component of membrane;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0004725//protein tyrosine phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0004438//phosphatidylinositol-3-phosphatase activity;GO:0052629//phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity","GO:2000785//regulation of autophagosome assembly;GO:0006470//protein dephosphorylation;GO:0006661//phosphatidylinositol biosynthetic process;GO:0046856//phosphatidylinositol dephosphorylation;GO:1904562//phosphatidylinositol 5-phosphate metabolic process;GO:0042149//cellular response to glucose starvation;GO:0016236//macroautophagy","K18082//myotubularin-related protein 3/4 [EC:3.1.3.48 3.1.3.64 3.1.3.95]","XP_016884520.1//PREDICTED: myotubularin-related protein 3 isoform X7 [Homo sapiens];XP_016884519.1//PREDICTED: myotubularin-related protein 3 isoform X4 [Homo sapiens];XP_016884518.1//PREDICTED: myotubularin-related protein 3 isoform X2 [Homo sapiens]","3//A2MP1;2//1"]
[9877,4914,18.09,11.76,-0.621304347784877,{"v":1.86169745577889e-19,"d":"1.86E-19"},"*",{"v":9.27702e-21,"d":"9.28E-21"},"ZC3H11A","GO:0005654//nucleoplasm","GO:0003723//RNA binding;GO:0046872//metal ion binding","GO:0016973//poly(A)+ mRNA export from nucleus;GO:0006406//mRNA export from nucleus;GO:0006369//termination of RNA polymerase II transcription;GO:0031124//mRNA 3'-end processing;GO:0006405//RNA export from nucleus","K03243//translation initiation factor 5B","NP_001337194.1//zinc finger CCCH domain-containing protein 11A isoform 2 [Homo sapiens];NP_055642.3//zinc finger CCCH domain-containing protein 11A isoform 1 [Homo sapiens]","1//3;5"]
[2803,7881,6.18,4.02,-0.620411336725446,{"v":1.41850304721879E-10,"d":"1.42E-10"},"*",{"v":1.436796E-11,"d":"1.44E-11"},"GOLGA4","GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005802//trans-Golgi network;GO:0005737//cytoplasm;GO:0000139//Golgi membrane","GO:0051020//GTPase binding","GO:0045773//positive regulation of axon extension;GO:0043001//Golgi to plasma membrane protein transport;GO:0016192//vesicle-mediated transport","K20283//golgin subfamily A member 4","NP_002069.2//golgin subfamily A member 4 isoform 2 [Homo sapiens];NP_001166184.1//golgin subfamily A member 4 isoform 1 [Homo sapiens]","1//3;4"]
[10724,5187,13.69,8.91,-0.619625109735977,{"v":4.49159695238095e-16,"d":"4.49E-16"},"*",{"v":2.89336e-17,"d":"2.89E-17"},"MGEA5","GO:0016020//membrane;GO:0005829//cytosol","GO:0016231//beta-N-acetylglucosaminidase activity","GO:0006044//N-acetylglucosamine metabolic process;GO:0006517//protein deglycosylation","K15719//protein O-GlcNAcase / histone acetyltransferase [EC:3.2.1.169 2.3.1.48]","XP_007962118.1//PREDICTED: bifunctional protein NCOAT isoform X1 [Chlorocebus sabaeus];XP_011906972.1//PREDICTED: protein O-GlcNAcase isoform X1 [Cercocebus atys]","1//3;3//A2MP1"]
[5756,3062,34.49,22.45,-0.619462683832344,{"v":1.16504169681159e-21,"d":"1.17E-21"},"*",{"v":5.03242e-23,"d":"5.03E-23"},"TWF1","GO:0005925//focal adhesion;GO:0032587//ruffle membrane;GO:0030016//myofibril;GO:0048471//perinuclear region of cytoplasm;GO:0030175//filopodium;GO:0005911//cell-cell junction;GO:0005829//cytosol;GO:0015629//actin cytoskeleton","GO:0004713//protein tyrosine kinase activity;GO:0005524//ATP binding;GO:0003785//actin monomer binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0032403//protein complex binding;GO:0045296//cadherin binding","GO:0042989//sequestering of actin monomers;GO:0043538//regulation of actin phosphorylation;GO:0051016//barbed-end actin filament capping;GO:0010613//positive regulation of cardiac muscle hypertrophy","K08870//twinfilin","AAH43148.2//Twinfilin, actin-binding protein, homolog 1 (Drosophila) [Homo sapiens];XP_003825794.1//PREDICTED: twinfilin-1 isoform X2 [Pan paniscus]","4;1//3"]
[134266,4105,5.48,3.57,-0.618251818931427,{"v":2.43783153387534E-5,"d":"2.44E-05"},"*",{"v":5.06826E-6,"d":"5.07E-06"},"GRPEL2","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion;GO:0001405//presequence translocase-associated import motor","GO:0051082//unfolded protein binding;GO:0051087//chaperone binding;GO:0000774//adenyl-nucleotide exchange factor activity;GO:0042803//protein homodimerization activity","GO:0006457//protein folding;GO:0030150//protein import into mitochondrial matrix","K03687//molecular chaperone GrpE","CAD38619.1//hypothetical protein, partial [Homo sapiens]","3//A2MP1"]
[84247,5355,10.91,7.11,-0.617729636704192,{"v":2.38398899346405e-12,"d":"2.38E-12"},"*",{"v":2.05506e-13,"d":"2.06E-13"},"RTL6","NA","NA","NA","K12012//tripartite motif-containing protein 35","NP_115663.2//retrotransposon Gag-like protein 6 [Homo sapiens]","2//1"]
[26512,5535,3.16,2.06,-0.617280220993884,{"v":1.8465252698609E-5,"d":"1.85E-05"},"*",{"v":3.73952e-06,"d":"3.74E-06"},"INTS6","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0015629//actin cytoskeleton;GO:0032039//integrator complex","GO:0004888//transmembrane signaling receptor activity","GO:0042795//snRNA transcription from RNA polymerase II promoter;GO:0016180//snRNA processing","K13143//integrator complex subunit 6","NP_036273.1//integrator complex subunit 6 isoform a [Homo sapiens];AAQ96237.1//LRRGT00024 [Rattus norvegicus]","1//3;2//1"]
[54843,3416,3.22,2.1,-0.616671360448494,0.0174632458111544,"*",0.00644896,"SYTL2","GO:0016020//membrane;GO:0070382//exocytic vesicle;GO:0005622//intracellular;GO:0042470//melanosome;GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0019897//extrinsic component of plasma membrane","GO:0005544//calcium-dependent phospholipid binding;GO:0042043//neurexin family protein binding;GO:0030276//clathrin binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0005509//calcium ion binding;GO:0019902//phosphatase binding;GO:0019905//syntaxin binding;GO:0001786//phosphatidylserine binding;GO:0017137//Rab GTPase binding","GO:0072659//protein localization to plasma membrane;GO:0070257//positive regulation of mucus secretion;GO:0006904//vesicle docking involved in exocytosis;GO:0016192//vesicle-mediated transport;GO:0006886//intracellular protein transport;GO:0006906//vesicle fusion;GO:0010923//negative regulation of phosphatase activity;GO:0006887//exocytosis","K17598//synaptotagmin-like protein","NP_116561.1//synaptotagmin-like protein 2 isoform a [Homo sapiens];XP_012360328.1//PREDICTED: synaptotagmin-like protein 2 isoform X10 [Nomascus leucogenys];NP_996813.1//synaptotagmin-like protein 2 isoform f [Homo sapiens];XP_016873427.1//PREDICTED: synaptotagmin-like protein 2 isoform X19 [Homo sapiens];XP_005274118.1//PREDICTED: synaptotagmin-like protein 2 isoform X14 [Homo sapiens];XP_016873428.1//PREDICTED: synaptotagmin-like protein 2 isoform X20 [Homo sapiens];NP_001156425.1//synaptotagmin-like protein 2 isoform i [Homo sapiens];NP_001156423.1//synaptotagmin-like protein 2 isoform g [Homo sapiens]","4;1//3;3//A2MP1;2//1"]
[134553,4424,12.35,8.06,-0.615659297944073,{"v":4.28579757666667E-14,"d":"4.29E-14"},"*",{"v":3.21958e-15,"d":"3.22E-15"},"C5orf24","NA","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K02927//large subunit ribosomal protein L40e;K15696//RING finger protein 113B;K17985//activating molecule in BECN1-regulated autophagy protein 1;K01064//wingless-type MMTV integration site family, member 9","XP_012360486.1//PREDICTED: UPF0461 protein C5orf24 homolog isoform X3 [Nomascus leucogenys];XP_012360484.1//PREDICTED: UPF0461 protein C5orf24 homolog isoform X1 [Nomascus leucogenys];EDL41223.1//RIKEN cDNA B230219D22, partial [Mus musculus]","1//3;3//A2MP1"]
[26054,6483,5.45,3.56,-0.614378988697891,{"v":5.16403962179199e-08,"d":"5.16E-08"},"*",{"v":7.18e-09,"d":"7.18E-09"},"SENP6","GO:0005654//nucleoplasm;GO:0005829//cytosol","GO:0008234//cysteine-type peptidase activity;GO:0016929//SUMO-specific protease activity","GO:0016925//protein sumoylation;GO:0070646//protein modification by small protein removal;GO:0090169//regulation of spindle assembly;GO:0090234//regulation of kinetochore assembly;GO:0016926//protein desumoylation","K08595//sentrin-specific protease 6 [EC:3.4.22.68]","NP_001291721.1//sentrin-specific protease 6 isoform 3 [Homo sapiens];NP_001093879.1//sentrin-specific protease 6 isoform 2 [Homo sapiens];NP_056386.2//sentrin-specific protease 6 isoform 1 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[5933,5916,7.11,4.65,-0.612618843624022,{"v":4.85999289963973e-09,"d":"4.86E-09"},"*",{"v":5.91146e-10,"d":"5.91E-10"},"RBL1","GO:0005654//nucleoplasm;GO:0005667//transcription factor complex","GO:1990841//promoter-specific chromatin binding;GO:0008134//transcription factor binding","GO:0006351//transcription, DNA-templated;GO:0010629//negative regulation of gene expression;GO:0016032//viral process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0016569//covalent chromatin modification;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0051726//regulation of cell cycle;GO:0007049//cell cycle;GO:0043550//regulation of lipid kinase activity","K04681//retinoblastoma-like protein 1","XP_006723905.1//PREDICTED: retinoblastoma-like protein 1 isoform X3 [Homo sapiens];XP_021776761.1//retinoblastoma-like protein 1 isoform X4 [Papio anubis];NP_002886.2//retinoblastoma-like protein 1 isoform a [Homo sapiens]","4;1//3;3//A2MP1"]
[254887,5323,1.85,1.21,-0.612518223241718,0.000232996146490336,"*",{"v":5.7352e-05,"d":"5.74E-05"},"ZDHHC23","GO:0016021//integral component of membrane","GO:0019706//protein-cysteine S-palmitoyltransferase activity","GO:0018345//protein palmitoylation;GO:0072659//protein localization to plasma membrane","K18932//palmitoyltransferase [EC:2.3.1.225]","NP_775841.2//palmitoyltransferase ZDHHC23 isoform c [Homo sapiens];NP_001307397.1//palmitoyltransferase ZDHHC23 isoform b [Homo sapiens];NP_001307396.1//palmitoyltransferase ZDHHC23 isoform a [Homo sapiens]","4;1//3"]
[4552,3291,15.49,10.14,-0.611279491786228,{"v":1.24142532445551E-10,"d":"1.24E-10"},"*",{"v":1.248886E-11,"d":"1.25E-11"},"MTRR","GO:0005829//cytosol","GO:0003958//NADPH-hemoprotein reductase activity;GO:0050660//flavin adenine dinucleotide binding;GO:0070402//NADPH binding;GO:0050444//aquacobalamin reductase (NADPH) activity;GO:0050661//NADP binding;GO:0010181//FMN binding;GO:0016723//oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor;GO:0030586//[methionine synthase] reductase activity;GO:0071949//FAD binding","GO:0043418//homocysteine catabolic process;GO:0055114//oxidation-reduction process;GO:0006306//DNA methylation;GO:0033353//S-adenosylmethionine cycle;GO:0006555//methionine metabolic process;GO:1904042//negative regulation of cystathionine beta-synthase activity;GO:0000096//sulfur amino acid metabolic process;GO:0032259//methylation;GO:0009235//cobalamin metabolic process;GO:0046655//folic acid metabolic process;GO:0009086//methionine biosynthetic process","K00597//methionine synthase reductase [EC:1.16.1.8]","NP_076915.2//methionine synthase reductase isoform 2 [Homo sapiens]","2//1"]
[84056,7521,3.13,2.05,-0.610538747427172,{"v":1.89418658243451e-05,"d":"1.89E-05"},"*",{"v":3.8479E-6,"d":"3.85E-06"},"KATNAL1","GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005874//microtubule;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0030496//midbody","GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0008568//microtubule-severing ATPase activity;GO:0008017//microtubule binding","GO:0051301//cell division;GO:0051013//microtubule severing;GO:0007049//cell cycle","K07767//katanin p60 ATPase-containing subunit A1 [EC:3.6.4.3]","NP_115492.1//katanin p60 ATPase-containing subunit A-like 1 [Homo sapiens]","4;2//1"]
[50507,4062,0.29,0.19,-0.610053481683986,0.458872484140234,"*",0.309726,"NOX4","GO:0005634//nucleus;GO:0005925//focal adhesion;GO:0016324//apical plasma membrane;GO:0071944//cell periphery;GO:0048471//perinuclear region of cytoplasm;GO:0001725//stress fiber;GO:0005730//nucleolus;GO:0043020//NADPH oxidase complex;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005739//mitochondrion;GO:0005886//plasma membrane","GO:0016174//NAD(P)H oxidase activity;GO:0009055//electron transfer activity;GO:0020037//heme binding;GO:0000166//nucleotide binding;GO:0072341//modified amino acid binding;GO:0019826//oxygen sensor activity;GO:0050660//flavin adenine dinucleotide binding;GO:0016175//superoxide-generating NADPH oxidase activity;GO:0016491//oxidoreductase activity","GO:0006801//superoxide metabolic process;GO:0051897//positive regulation of protein kinase B signaling;GO:0055114//oxidation-reduction process;GO:0071320//cellular response to cAMP;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0043065//positive regulation of apoptotic process;GO:0042554//superoxide anion generation;GO:0014911//positive regulation of smooth muscle cell migration;GO:0008285//negative regulation of cell proliferation;GO:0045453//bone resorption;GO:0000902//cell morphogenesis;GO:0055007//cardiac muscle cell differentiation;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0043406//positive regulation of MAP kinase activity;GO:0007569//cell aging;GO:0072593//reactive oxygen species metabolic process;GO:0071480//cellular response to gamma radiation;GO:0001666//response to hypoxia;GO:0006954//inflammatory response;GO:0071333//cellular response to glucose stimulus;GO:0051496//positive regulation of stress fiber assembly;GO:0010467//gene expression;GO:0034599//cellular response to oxidative stress;GO:0050667//homocysteine metabolic process;GO:2000573//positive regulation of DNA biosynthetic process;GO:0070374//positive regulation of ERK1 and ERK2 cascade","K21423//NADPH oxidase 4 [EC:1.6.3.-]","XP_006718912.1//PREDICTED: NADPH oxidase 4 isoform X2 [Homo sapiens];NP_001278858.1//NADPH oxidase 4 isoform f [Homo sapiens];NP_001137309.1//NADPH oxidase 4 isoform c [Homo sapiens];NP_001137308.1//NADPH oxidase 4 isoform b [Homo sapiens];NP_001278856.1//NADPH oxidase 4 isoform e [Homo sapiens];NP_058627.1//NADPH oxidase 4 isoform a [Homo sapiens]","4;1//3;2//1"]
[8690,3565,1.8,1.18,-0.609210046967833,0.0310863721212121,"*",0.01233024,"JRKL","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein;K09229//KRAB and SCAN domains-containing zinc finger protein;K19326//nesprin-1;K05164//interleukin 17 receptor A","XP_017360779.1//PREDICTED: jerky protein homolog-like [Cebus capucinus imitator]","1//3;3//A2MP1"]
[122809,6922,3.64,2.39,-0.606927832217948,{"v":6.37317445693382e-06,"d":"6.37E-06"},"*",{"v":1.199708e-06,"d":"1.20E-06"},"SOCS4","GO:0005622//intracellular;GO:0005737//cytoplasm","GO:0004860//protein kinase inhibitor activity","GO:0040008//regulation of growth;GO:0016567//protein ubiquitination;GO:0046426//negative regulation of JAK-STAT cascade;GO:0035556//intracellular signal transduction;GO:0019221//cytokine-mediated signaling pathway;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0007175//negative regulation of epidermal growth factor-activated receptor activity","K04697//suppressor of cytokine signaling 4","NP_543143.1//suppressor of cytokine signaling 4 [Homo sapiens]","1//3;2//1"]
[9633,3491,2.65,1.74,-0.606905053601833,0.0108793971372197,"*",0.00379696,"TESMIN","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0046872//metal ion binding","GO:0006875//cellular metal ion homeostasis;GO:0030154//cell differentiation;GO:0007275//multicellular organism development;GO:0007283//spermatogenesis;GO:0010038//response to metal ion","K16628//collagen, type VII, alpha;K21776//protein lin-54","EAW74718.1//metallothionein-like 5, testis-specific (tesmin), isoform CRA_a [Homo sapiens]","1//3;3//A2MP1"]
[23215,10394,23.61,15.52,-0.605269484041515,{"v":5.70853519833333e-48,"d":"5.71E-48"},"*",{"v":8.57674e-50,"d":"8.58E-50"},"PRRC2C","GO:0016020//membrane","GO:0003723//RNA binding;GO:0008022//protein C-terminus binding","GO:0002244//hematopoietic progenitor cell differentiation","K22016//mucin-3/17","NP_055987.2//protein PRRC2C [Homo sapiens]","3//A2MP1"]
[1737,4352,14.85,9.77,-0.604032463719743,{"v":4.48634851313756e-13,"d":"4.49E-13"},"*",{"v":3.63424e-14,"d":"3.63E-14"},"DLAT","GO:0005759//mitochondrial matrix;GO:0045254//pyruvate dehydrogenase complex;GO:0043209//myelin sheath;GO:0005739//mitochondrion;GO:0005967//mitochondrial pyruvate dehydrogenase complex","GO:0004742//dihydrolipoyllysine-residue acetyltransferase activity;GO:0034604//pyruvate dehydrogenase (NAD+) activity;GO:0042802//identical protein binding","GO:0006099//tricarboxylic acid cycle;GO:0006006//glucose metabolic process;GO:0006090//pyruvate metabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0030431//sleep;GO:0010510//regulation of acetyl-CoA biosynthetic process from pyruvate;GO:0006086//acetyl-CoA biosynthetic process from pyruvate","K00627//pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase) [EC:2.3.1.12]","NP_001922.2//dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial precursor [Homo sapiens]",4]
[3667,8743,13.69,9.01,-0.603523435444361,{"v":1.15924923294893E-23,"d":"1.16E-23"},"*",{"v":4.40506e-25,"d":"4.41E-25"},"IRS1","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005901//caveola;GO:0005899//insulin receptor complex;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0043548//phosphatidylinositol 3-kinase binding;GO:0005068//transmembrane receptor protein tyrosine kinase adaptor activity;GO:0042169//SH2 domain binding;GO:0046934//phosphatidylinositol-4,5-bisphosphate 3-kinase activity;GO:0005080//protein kinase C binding;GO:0016303//1-phosphatidylinositol-3-kinase activity;GO:0001784//phosphotyrosine residue binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0004871//signal transducer activity;GO:0005159//insulin-like growth factor receptor binding;GO:0005158//insulin receptor binding","GO:2001275//positive regulation of glucose import in response to insulin stimulus;GO:0008286//insulin receptor signaling pathway;GO:0046628//positive regulation of insulin receptor signaling pathway;GO:0048009//insulin-like growth factor receptor signaling pathway;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0042593//glucose homeostasis;GO:0046326//positive regulation of glucose import;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0019216//regulation of lipid metabolic process;GO:0010907//positive regulation of glucose metabolic process;GO:0000165//MAPK cascade;GO:0032000//positive regulation of fatty acid beta-oxidation;GO:0007165//signal transduction;GO:0032868//response to insulin;GO:0014066//regulation of phosphatidylinositol 3-kinase signaling;GO:0043434//response to peptide hormone;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0038111//interleukin-7-mediated signaling pathway;GO:0032869//cellular response to insulin stimulus;GO:0046676//negative regulation of insulin secretion;GO:0045725//positive regulation of glycogen biosynthetic process;GO:0048015//phosphatidylinositol-mediated signaling;GO:0008284//positive regulation of cell proliferation","K16172//insulin receptor substrate 1","NP_005535.1//insulin receptor substrate 1 [Homo sapiens]","2//1"]
[57460,6201,5.51,3.63,-0.602082770575407,{"v":2.33501944228382E-7,"d":"2.34E-07"},"*",{"v":3.53308e-08,"d":"3.53E-08"},"PPM1H","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm","GO:0004721//phosphoprotein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity","NA","K17503//protein phosphatase 1H [EC:3.1.3.16]","XP_003906758.1//LOW QUALITY PROTEIN: protein phosphatase 1H [Papio anubis]","1//3"]
[79677,5188,10.85,7.16,-0.599663550067585,{"v":1.87798912264151e-11,"d":"1.88E-11"},"*",{"v":1.74467e-12,"d":"1.74E-12"},"SMC6","GO:0030915//Smc5-Smc6 complex;GO:0016605//PML body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000781//chromosome, telomeric region;GO:0016607//nuclear speck;GO:0005622//intracellular;GO:0000803//sex chromosome;GO:0035861//site of double-strand break;GO:0035061//interchromatin granule","GO:0005524//ATP binding;GO:0031625//ubiquitin protein ligase binding","GO:0000722//telomere maintenance via recombination;GO:0090398//cellular senescence;GO:0051984//positive regulation of chromosome segregation;GO:0000724//double-strand break repair via homologous recombination;GO:0006974//cellular response to DNA damage stimulus","K20283//golgin subfamily A member 4;K20478//golgin subfamily B member 1","NP_078900.1//structural maintenance of chromosomes protein 6 [Homo sapiens]","1//3;5"]
[6787,5871,6.44,4.25,-0.599597847089553,{"v":2.75202138959212E-8,"d":"2.75E-08"},"*",{"v":3.67476e-09,"d":"3.67E-09"},"NEK4","GO:0036064//ciliary basal body;GO:0035869//ciliary transition zone;GO:0035253//ciliary rootlet;GO:0005737//cytoplasm;GO:0097014//ciliary plasm","GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0030145//manganese ion binding","GO:0023014//signal transduction by protein phosphorylation;GO:0000278//mitotic cell cycle;GO:0007346//regulation of mitotic cell cycle;GO:0006468//protein phosphorylation;GO:0032147//activation of protein kinase activity;GO:2001020//regulation of response to DNA damage stimulus;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051301//cell division;GO:2000772//regulation of cellular senescence;GO:0031098//stress-activated protein kinase signaling cascade;GO:0006974//cellular response to DNA damage stimulus;GO:0042981//regulation of apoptotic process;GO:1900062//regulation of replicative cell aging","K08857//NIMA (never in mitosis gene a)-related kinase 1/4/5 [EC:2.7.11.1]","NP_001180462.1//serine/threonine-protein kinase Nek4 isoform 2 [Homo sapiens];NP_003148.2//serine/threonine-protein kinase Nek4 isoform 1 [Homo sapiens];XP_007982729.1//PREDICTED: serine/threonine-protein kinase Nek4 isoform X2 [Chlorocebus sabaeus]","1//3;2//1;5"]
[343035,4288,0.53,0.35,-0.598637437618233,0.256176892988442,"*",0.1456972,"RD3","NA","NA","GO:0060041//retina development in camera-type eye;GO:0050896//response to stimulus;GO:0007601//visual perception","K05727//dedicator of cytokinesis protein 3;K06238//collagen, type VI, alpha","XP_016856640.1//PREDICTED: protein RD3 isoform X1 [Homo sapiens]","1//3;2//1"]
[255308,2096,0.56,0.37,-0.597901556428654,0.459085378491231,"*",0.309726,"EIF2S3B","NA","NA","NA","K03242//translation initiation factor 2 subunit 3","AAH87847.1//Unknown (protein for IMAGE:30389268), partial [Homo sapiens];Q2VIR3.2//PUTATIVE PSEUDOGENE: RecName: Full=Putative eukaryotic translation initiation factor 2 subunit 3-like protein; AltName: Full=Eukaryotic translation initiation factor 2 subunit gamma A; Short=eIF-2-gamma A; Short=eIF-2gA","1//3"]
[8317,3201,5.02,3.32,-0.596504122603847,0.000718772555463347,"*",0.0001951944,"CDC7","GO:0072686//mitotic spindle;GO:0045171//intercellular bridge;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0016301//kinase activity","GO:0000727//double-strand break repair via break-induced replication;GO:0006260//DNA replication;GO:0006270//DNA replication initiation;GO:0008360//regulation of cell shape;GO:0010571//positive regulation of nuclear cell cycle DNA replication;GO:0044770//cell cycle phase transition;GO:0018105//peptidyl-serine phosphorylation;GO:0051301//cell division;GO:0010971//positive regulation of G2/M transition of mitotic cell cycle;GO:0000082//G1/S transition of mitotic cell cycle;GO:0006909//phagocytosis;GO:0008284//positive regulation of cell proliferation","K02214//cell division control protein 7 [EC:2.7.11.1]","XP_018884451.1//PREDICTED: cell division cycle 7-related protein kinase isoform X1 [Gorilla gorilla gorilla]","1//3;3//A2MP1"]
[348801,2233,1.51,1,-0.594548549550354,0.185113975151443,"*",0.0975632,"LNP1","NA","NA","NA","NA","XP_018879099.1//PREDICTED: leukemia NUP98 fusion partner 1 isoform X2 [Gorilla gorilla gorilla]","1//3"]
[5069,10995,8.74,5.79,-0.594069931511362,{"v":1.28311482719812e-18,"d":"1.28E-18"},"*",{"v":6.85174e-20,"d":"6.85E-20"},"PAPPA","GO:0005615//extracellular space;GO:0016021//integral component of membrane;GO:0005576//extracellular region","GO:0008237//metallopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding","GO:0044267//cellular protein metabolic process;GO:0007565//female pregnancy;GO:0051384//response to glucocorticoid;GO:0032354//response to follicle-stimulating hormone","K07762//pappalysin-1 [EC:3.4.24.79]","NP_002572.2//pappalysin-1 preproprotein [Homo sapiens]",4]
[120526,3000,6.17,4.09,-0.593169646207669,2.99345053071375E-4,"*",{"v":7.53516e-05,"d":"7.54E-05"},"DNAJC24","GO:0005856//cytoskeleton;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0001671//ATPase activator activity;GO:0008270//zinc ion binding;GO:0008198//ferrous iron binding","GO:0017183//peptidyl-diphthamide biosynthetic process from peptidyl-histidine;GO:0032781//positive regulation of ATPase activity;GO:0055114//oxidation-reduction process;GO:0061077//chaperone-mediated protein folding","K17867//diphthamide biosynthesis protein 4","NP_859057.4//dnaJ homolog subfamily C member 24 [Homo sapiens]",4]
[1290,6930,14.65,9.72,-0.591872445703829,{"v":1.87611322961104E-19,"d":"1.88E-19"},"*",{"v":9.3606e-21,"d":"9.36E-21"},"COL5A2","GO:0031012//extracellular matrix;GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0005588//collagen type V trimer;GO:0005576//extracellular region","GO:0046872//metal ion binding;GO:0005201//extracellular matrix structural constituent;GO:0046332//SMAD binding","GO:0043588//skin development;GO:0030199//collagen fibril organization;GO:0001503//ossification;GO:0048592//eye morphogenesis;GO:1903225//negative regulation of endodermal cell differentiation;GO:0071230//cellular response to amino acid stimulus;GO:0030198//extracellular matrix organization;GO:0001501//skeletal system development;GO:0030574//collagen catabolic process","K19721//collagen, type V/XI/XXIV/XXVII, alpha","BAD92282.1//alpha 2 type V collagen preproprotein variant, partial [Homo sapiens]",4]
[84912,6816,12.32,8.18,-0.590829507753152,{"v":3.87286660273973e-16,"d":"3.87E-16"},"*",{"v":2.47782E-17,"d":"2.48E-17"},"SLC35B4","GO:0005783//endoplasmic reticulum;GO:0030173//integral component of Golgi membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0005462//UDP-N-acetylglucosamine transmembrane transporter activity;GO:0005457//GDP-fucose transmembrane transporter activity;GO:0005464//UDP-xylose transmembrane transporter activity","GO:0015790//UDP-xylose transmembrane transport;GO:0015783//GDP-fucose transmembrane transport;GO:0008643//carbohydrate transport;GO:1990569//UDP-N-acetylglucosamine transmembrane transport;GO:0006111//regulation of gluconeogenesis","K15278//solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4","NP_116215.1//UDP-xylose and UDP-N-acetylglucosamine transporter [Homo sapiens]",4]
[10827,4553,3.13,2.08,-0.589579128791526,0.00173686032123024,"*",0.000509076,"FAM114A2","NA","GO:0017076//purine nucleotide binding","NA","NA","NP_061161.2//protein FAM114A2 isoform 1 [Homo sapiens];XP_011740774.1//PREDICTED: protein FAM114A2 isoform X1 [Macaca nemestrina];NP_001304924.1//protein FAM114A2 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[219654,4933,1.88,1.25,-0.58880456701555,0.0150062756824079,"*",0.00543078,"ZCCHC24","NA","GO:0003723//RNA binding;GO:0008270//zinc ion binding;GO:0003676//nucleic acid binding","NA","K10955//mucin-2","XP_017720713.1//PREDICTED: zinc finger CCHC domain-containing protein 24 [Rhinopithecus bieti]","3//A2MP1"]
[55175,7410,2.81,1.87,-0.587531860333289,1.17927143731544E-4,"*",{"v":2.74996E-5,"d":"2.75E-05"},"KLHL11","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0019005//SCF ubiquitin ligase complex","GO:0031625//ubiquitin protein ligase binding","GO:0043687//post-translational protein modification;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0030162//regulation of proteolysis;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process","K10449//kelch-like protein 11","XP_004434534.2//PREDICTED: kelch-like protein 11 [Ceratotherium simum simum]","2//1"]
[27125,9580,5.48,3.65,-0.586279429193147,{"v":2.33389254294294e-10,"d":"2.33E-10"},"*",{"v":2.43266E-11,"d":"2.43E-11"},"AFF4","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0008023//transcription elongation factor complex;GO:0035327//transcriptionally active chromatin;GO:0001650//fibrillar center","GO:0003700//DNA binding transcription factor activity","GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0007286//spermatid development;GO:0006366//transcription from RNA polymerase II promoter","K15185//AF4/FMR2 family member 4","NP_055238.1//AF4/FMR2 family member 4 [Homo sapiens]","3//A2MP1"]
[340578,2612,0.09,0.06,-0.584962500721156,0.782986118466899,"*",0.689316,"DCAF12L2","NA","NA","NA","K11803//WD repeat-containing protein 40A","XP_012331827.1//DDB1- and CUL4-associated factor 12-like protein 2 [Aotus nancymaae]","2//1"]
[1124,3150,0.09,0.06,-0.584962500721156,0.782318563694494,"*",0.689316,"CHN2","GO:0016020//membrane;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005737//cytoplasm","GO:0005070//SH3/SH2 adaptor activity;GO:0046872//metal ion binding;GO:0005096//GTPase activator activity","GO:0043087//regulation of GTPase activity;GO:0035556//intracellular signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction","K20630//chimaerin","NP_001280010.1//beta-chimaerin isoform 14 [Homo sapiens];NP_001280004.1//beta-chimaerin isoform 8 [Homo sapiens];NP_001280000.1//beta-chimaerin isoform 5 [Homo sapiens];NP_001279998.1//beta-chimaerin isoform 3 [Homo sapiens];NP_001280002.1//beta-chimaerin isoform 7 [Homo sapiens];EHH17412.1//hypothetical protein EGK_13814 [Macaca mulatta];XP_011937965.1//PREDICTED: LOW QUALITY PROTEIN: beta-chimaerin-like [Cercocebus atys];NP_004058.1//beta-chimaerin isoform 2 [Homo sapiens];XP_014335491.1//PREDICTED: beta-chimaerin isoform X6 [Bos mutus];NP_001279999.1//beta-chimaerin isoform 4 [Homo sapiens];XP_005901472.2//PREDICTED: beta-chimaerin isoform X3 [Bos mutus];XP_011729588.1//PREDICTED: beta-chimaerin isoform X9 [Macaca nemestrina]","1//3;3//A2MP1;2//1"]
[154214,11324,1.44,0.96,-0.584962500721156,0.000778453841226264,"*",2.1301E-4,"RNF217","GO:0000151//ubiquitin ligase complex;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005737//cytoplasm","GO:0061630//ubiquitin protein ligase activity;GO:0046872//metal ion binding;GO:0004842//ubiquitin-protein transferase activity;GO:0031624//ubiquitin conjugating enzyme binding","GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0000209//protein polyubiquitination","K11977//E3 ubiquitin-protein ligase RNF217 [EC:2.3.2.27]","NP_689766.1//probable E3 ubiquitin-protein ligase RNF217 isoform b [Homo sapiens];NP_001273327.1//probable E3 ubiquitin-protein ligase RNF217 isoform a [Homo sapiens]","4;2//1"]
[85442,3278,1.11,0.74,-0.584962500721156,0.103315283817649,"*",0.0485208,"KNDC1","GO:0030425//dendrite;GO:0043204//perikaryon;GO:0043025//neuronal cell body;GO:0032045//guanyl-nucleotide exchange factor complex","GO:0005088//Ras guanyl-nucleotide exchange factor activity","GO:0050773//regulation of dendrite development;GO:0007264//small GTPase mediated signal transduction;GO:0001934//positive regulation of protein phosphorylation;GO:0048814//regulation of dendrite morphogenesis;GO:0021707//cerebellar granule cell differentiation","K06689//ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23];K12581//CCR4-NOT transcription complex subunit 7/8;K16628//collagen, type VII, alpha;K04957//hyperpolarization activated cyclic nucleotide-gated potassium channel 4;K11447//histone demethylase [EC:1.14.11.-];K14317//nuclear pore complex protein Nup214;K01064//wingless-type MMTV integration site family, member 9","NP_689856.6//protein very KIND isoform 1 [Homo sapiens];NP_001334793.1//protein very KIND isoform 2 [Homo sapiens];NP_001334795.1//protein very KIND isoform 4 [Homo sapiens];NP_001334794.1//protein very KIND isoform 3 [Homo sapiens]","1//3;7"]
[23220,5478,2.67,1.78,-0.584962500721156,0.00280872361780318,"*",8.6122E-4,"DTX4","GO:0005829//cytosol","GO:0008270//zinc ion binding;GO:0004842//ubiquitin-protein transferase activity","GO:0032479//regulation of type I interferon production;GO:0007219//Notch signaling pathway","K06058//deltex [EC:2.3.2.27]","XP_003275396.1//PREDICTED: E3 ubiquitin-protein ligase DTX4 [Nomascus leucogenys];NP_055992.1//E3 ubiquitin-protein ligase DTX4 isoform 1 [Homo sapiens]","1//3"]
[51168,11876,0.03,0.02,-0.584962500721156,0.813017131242579,"*",0.728682,"MYO15A","GO:0070062//extracellular exosome;GO:0016459//myosin complex;GO:0032420//stereocilium;GO:0005737//cytoplasm","GO:0003779//actin binding;GO:0005524//ATP binding;GO:0003774//motor activity;GO:0005516//calmodulin binding","GO:0007626//locomotory behavior;GO:0042472//inner ear morphogenesis;GO:0007605//sensory perception of sound","K10361//myosin XV","NP_057323.3//unconventional myosin-XV [Homo sapiens]","3//A2MP1"]
[8820,1182,0.21,0.14,-0.584962500721156,0.781707637654409,"*",0.689316,"HESX1","GO:0005634//nucleus","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:0008022//protein C-terminus binding;GO:0047485//protein N-terminus binding;GO:0003682//chromatin binding;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0006355//regulation of transcription, DNA-templated;GO:0021983//pituitary gland development;GO:0006351//transcription, DNA-templated;GO:0048853//forebrain morphogenesis;GO:0007420//brain development;GO:0030916//otic vesicle formation;GO:0043584//nose development","K09354//homeobox protein expressed in ES cells 1","XP_003257267.1//PREDICTED: homeobox expressed in ES cells 1 [Nomascus leucogenys]","2//1"]
[2301,2000,0.12,0.08,-0.584962500721156,0.781153077752554,"*",0.689316,"FOXE3","GO:0005634//nucleus;GO:0005667//transcription factor complex","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0003677//DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0009653//anatomical structure morphogenesis;GO:0001654//eye development;GO:0030154//cell differentiation;GO:0002930//trabecular meshwork development;GO:0043066//negative regulation of apoptotic process;GO:0061303//cornea development in camera-type eye;GO:0042789//mRNA transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:1902747//negative regulation of lens fiber cell differentiation;GO:0061072//iris morphogenesis;GO:2001111//positive regulation of lens epithelial cell proliferation;GO:0071157//negative regulation of cell cycle arrest;GO:0061073//ciliary body morphogenesis;GO:0048468//cell development;GO:0002088//lens development in camera-type eye","K09398//forkhead box protein E","NP_036318.1//forkhead box protein E3 [Homo sapiens]","2//1"]
[90381,6688,9.37,6.26,-0.581886390726568,{"v":6.23313326877193e-12,"d":"6.23E-12"},"*",{"v":5.56042e-13,"d":"5.56E-13"},"TICRR","GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0003682//chromatin binding","GO:0033314//mitotic DNA replication checkpoint;GO:0000075//cell cycle checkpoint;GO:0030174//regulation of DNA-dependent DNA replication initiation;GO:0010212//response to ionizing radiation;GO:0006281//DNA repair;GO:0006260//DNA replication;GO:0001731//formation of translation preinitiation complex","K10955//mucin-2","NP_689472.3//treslin isoform 2 [Homo sapiens];NP_001294954.1//treslin isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[7110,6895,1.81,1.21,-0.580982649808611,0.00534743973004242,"*",1.73606E-3,"TMF1","GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0000139//Golgi membrane","GO:0003677//DNA binding;GO:0003712//transcription cofactor activity","GO:0030317//flagellated sperm motility;GO:0006355//regulation of transcription, DNA-templated;GO:0007289//spermatid nucleus differentiation;GO:0010629//negative regulation of gene expression;GO:0043066//negative regulation of apoptotic process;GO:0042742//defense response to bacterium;GO:0001819//positive regulation of cytokine production;GO:0006366//transcription from RNA polymerase II promoter;GO:0061136//regulation of proteasomal protein catabolic process;GO:0001675//acrosome assembly;GO:0071407//cellular response to organic cyclic compound;GO:0033327//Leydig cell differentiation;GO:0032275//luteinizing hormone secretion;GO:2000845//positive regulation of testosterone secretion","K20286//TATA element modulatory factor","BAD92346.1//TATA element modulatory factor 1 variant, partial [Homo sapiens]","2//1"]
[5089,3231,16.07,10.75,-0.580033269198271,{"v":6.04083129760547e-10,"d":"6.04E-10"},"*",{"v":6.63304e-11,"d":"6.63E-11"},"PBX2","GO:0005634//nucleus;GO:0005667//transcription factor complex","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0008134//transcription factor binding","GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0009954//proximal/distal pattern formation;GO:0030326//embryonic limb morphogenesis","K15609//pre-B-cell leukemia transcription factor 2","NP_002577.2//pre-B-cell leukemia transcription factor 2 [Homo sapiens]",4]
[57464,4757,5.57,3.73,-0.578501697084794,{"v":2.55933820411056e-06,"d":"2.56E-06"},"*",{"v":4.52138e-07,"d":"4.52E-07"},"STRIP2","GO:0005829//cytosol;GO:0005737//cytoplasm","NA","GO:0016477//cell migration;GO:0007010//cytoskeleton organization;GO:0008360//regulation of cell shape","K12581//CCR4-NOT transcription complex subunit 7/8","EAL24101.1//family with sequence similarity 40, member B [Homo sapiens]","1//3;2//1"]
[201895,5395,9.62,6.45,-0.576737733459425,{"v":3.10240302105263e-09,"d":"3.10E-09"},"*",{"v":3.6901E-10,"d":"3.69E-10"},"SMIM14","GO:0016021//integral component of membrane","NA","NA","K11447//histone demethylase [EC:1.14.11.-]","XP_012864548.1//PREDICTED: small integral membrane protein 14 isoform X1 [Dipodomys ordii]","1//3;2//1"]
[54585,4075,2.49,1.67,-0.576297639594029,0.0120476264423588,"*",0.00425898,"LZTFL1","GO:0005829//cytosol","GO:0042802//identical protein binding;GO:0032403//protein complex binding","GO:1903565//negative regulation of protein localization to cilium;GO:1903568//negative regulation of protein localization to ciliary membrane","K19400//leucine zipper transcription factor-like protein 1","NP_001263308.1//leucine zipper transcription factor-like protein 1 isoform 3 [Homo sapiens];XP_003257022.1//PREDICTED: leucine zipper transcription factor-like protein 1 isoform X1 [Nomascus leucogenys];XP_516411.4//PREDICTED: leucine zipper transcription factor-like protein 1 isoform X1 [Pan troglodytes]","1//3;3//A2MP1"]
[64411,5281,4.01,2.69,-0.575996063898296,0.000142789390521327,"*",{"v":3.39498e-05,"d":"3.39E-05"},"ARAP3","GO:0001726//ruffle;GO:0005856//cytoskeleton;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0030027//lamellipodium;GO:0005737//cytoplasm","GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0046872//metal ion binding;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding;GO:0005096//GTPase activator activity","GO:0007165//signal transduction;GO:0035021//negative regulation of Rac protein signal transduction;GO:0007010//cytoskeleton organization;GO:0030336//negative regulation of cell migration;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0008360//regulation of cell shape;GO:0035024//negative regulation of Rho protein signal transduction;GO:0016192//vesicle-mediated transport","K12490//Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3","NP_071926.4//arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 [Homo sapiens]",5]
[115209,1953,5.51,3.7,-0.574527048054845,0.00990272183433025,"*",0.00342014,"OMA1","GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane","GO:0046872//metal ion binding;GO:0004222//metalloendopeptidase activity","GO:0006006//glucose metabolic process;GO:0042407//cristae formation;GO:0002024//diet induced thermogenesis;GO:0006950//response to stress;GO:0010637//negative regulation of mitochondrial fusion;GO:0097009//energy homeostasis;GO:0006515//protein quality control for misfolded or incompletely synthesized proteins;GO:0034982//mitochondrial protein processing;GO:0042981//regulation of apoptotic process;GO:0006629//lipid metabolic process","K11865//protein MYSM1","NP_660286.1//metalloendopeptidase OMA1, mitochondrial precursor [Homo sapiens]",4]
[51141,2659,2.56,1.72,-0.573735245297902,0.0325802989496786,"*",0.0130105,"INSIG2","GO:0032937//SREBP-SCAP-Insig complex;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0008134//transcription factor binding","GO:0008203//cholesterol metabolic process;GO:0006641//triglyceride metabolic process;GO:0032868//response to insulin;GO:0010894//negative regulation of steroid biosynthetic process;GO:0006695//cholesterol biosynthetic process;GO:0032933//SREBP signaling pathway;GO:0060363//cranial suture morphogenesis;GO:0006991//response to sterol depletion;GO:0042472//inner ear morphogenesis;GO:0042474//middle ear morphogenesis;GO:0045717//negative regulation of fatty acid biosynthetic process;GO:0060021//palate development;GO:0070542//response to fatty acid","NA","NP_057217.2//insulin-induced gene 2 protein isoform a [Homo sapiens];AAD43048.1//insulin induced protein 2 [Homo sapiens];XP_017355724.1//PREDICTED: insulin-induced gene 2 protein isoform X5 [Cebus capucinus imitator];XP_004004796.2//PREDICTED: LOW QUALITY PROTEIN: insulin-induced gene 2 protein isoform X1 [Ovis aries]","1//3;3//A2MP1"]
[57546,7117,4.42,2.97,-0.573583438590666,{"v":3.49470396536197e-06,"d":"3.49E-06"},"*",{"v":6.31602e-07,"d":"6.32E-07"},"PDP2","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0046872//metal ion binding;GO:0004741//[pyruvate dehydrogenase (lipoamide)] phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity","GO:0010510//regulation of acetyl-CoA biosynthetic process from pyruvate","K01102//pyruvate dehydrogenase phosphatase [EC:3.1.3.43]","NP_065837.1//[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial precursor [Homo sapiens];XP_007991796.1//PREDICTED: [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial isoform X1 [Chlorocebus sabaeus]","1//3;3//A2MP1"]
[10721,8787,2.29,1.54,-0.572417247402043,0.000251239846301439,"*",{"v":6.22988e-05,"d":"6.23E-05"},"POLQ","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0005524//ATP binding;GO:0051575//5'-deoxyribose-5-phosphate lyase activity;GO:0042802//identical protein binding;GO:0043142//single-stranded DNA-dependent ATPase activity;GO:0003887//DNA-directed DNA polymerase activity;GO:0003684//damaged DNA binding;GO:0003682//chromatin binding","GO:0006281//DNA repair;GO:0006284//base-excision repair;GO:0016446//somatic hypermutation of immunoglobulin genes;GO:0051260//protein homooligomerization;GO:0006302//double-strand break repair;GO:2000042//negative regulation of double-strand break repair via homologous recombination;GO:0006261//DNA-dependent DNA replication;GO:0097681//double-strand break repair via alternative nonhomologous end joining;GO:0000724//double-strand break repair via homologous recombination;GO:0006974//cellular response to DNA damage stimulus","K02349//DNA polymerase theta [EC:2.7.7.7]","EAW79510.1//polymerase (DNA directed), theta, isoform CRA_a [Homo sapiens]","3//A2MP1"]
[5738,6319,6.18,4.16,-0.571023309763282,{"v":1.33595772550364e-07,"d":"1.34E-07"},"*",{"v":1.951164e-08,"d":"1.95E-08"},"PTGFRN","GO:0009986//cell surface;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane","NA","GO:0034389//lipid particle organization","K06729//prostaglandin F2 receptor negative regulator","NP_065173.2//prostaglandin F2 receptor negative regulator precursor [Homo sapiens]","3//A2MP1"]
[210,3238,8.55,5.76,-0.569855608330948,{"v":1.4788825768262E-5,"d":"1.48E-05"},"*",{"v":2.94036E-6,"d":"2.94E-06"},"ALAD","GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005829//cytosol;GO:1904813//ficolin-1-rich granule lumen;GO:0005576//extracellular region;GO:0005839//proteasome core complex","GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0008270//zinc ion binding;GO:1904854//proteasome core complex binding;GO:0003824//catalytic activity;GO:0004655//porphobilinogen synthase activity","GO:0010044//response to aluminum ion;GO:0043200//response to amino acid;GO:0032496//response to lipopolysaccharide;GO:0051260//protein homooligomerization;GO:0006779//porphyrin-containing compound biosynthetic process;GO:0045471//response to ethanol;GO:0006783//heme biosynthetic process;GO:0033197//response to vitamin E;GO:0010269//response to selenium ion;GO:0043312//neutrophil degranulation;GO:0046685//response to arsenic-containing substance;GO:0071353//cellular response to interleukin-4;GO:0051384//response to glucocorticoid;GO:1901799//negative regulation of proteasomal protein catabolic process;GO:0010266//response to vitamin B1;GO:0042493//response to drug;GO:0010212//response to ionizing radiation;GO:0014823//response to activity;GO:0006782//protoporphyrinogen IX biosynthetic process;GO:0010043//response to zinc ion;GO:0010039//response to iron ion;GO:0009635//response to herbicide;GO:0001666//response to hypoxia;GO:0071284//cellular response to lead ion;GO:0006979//response to oxidative stress;GO:0046686//response to cadmium ion;GO:0032025//response to cobalt ion;GO:0046689//response to mercury ion;GO:0051597//response to methylmercury;GO:0070542//response to fatty acid;GO:0070541//response to platinum ion","K01698//porphobilinogen synthase [EC:4.2.1.24]","XP_007966544.1//PREDICTED: delta-aminolevulinic acid dehydratase isoform X1 [Chlorocebus sabaeus];XP_003911382.1//delta-aminolevulinic acid dehydratase isoform X1 [Papio anubis]","1//3;2//1;5"]
[249,2332,0.46,0.31,-0.569365645670138,0.372419825105783,"*",0.231416,"ALPL","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0031225//anchored component of membrane;GO:0005578//proteinaceous extracellular matrix;GO:0065010//extracellular membrane-bounded organelle;GO:0005576//extracellular region;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0046872//metal ion binding;GO:0016462//pyrophosphatase activity;GO:0004035//alkaline phosphatase activity","GO:0001958//endochondral ossification;GO:0001649//osteoblast differentiation;GO:0006501//C-terminal protein lipidation;GO:0003006//developmental process involved in reproduction;GO:0032496//response to lipopolysaccharide;GO:0071529//cementum mineralization;GO:0033280//response to vitamin D;GO:0046677//response to antibiotic;GO:0071407//cellular response to organic cyclic compound;GO:0001501//skeletal system development;GO:0051384//response to glucocorticoid","K01077//alkaline phosphatase [EC:3.1.3.1]","NP_001170991.1//alkaline phosphatase, tissue-nonspecific isozyme isoform 3 [Homo sapiens];BAD93051.1//ALPL protein variant, partial [Homo sapiens]","3//A2MP1;2//1;5"]
[80267,6670,2.7,1.82,-0.569020956852135,0.000602274779583236,"*",0.0001610314,"EDEM3","GO:0016020//membrane;GO:0005788//endoplasmic reticulum lumen;GO:0005783//endoplasmic reticulum;GO:0044322//endoplasmic reticulum quality control compartment","GO:0004571//mannosyl-oligosaccharide 1,2-alpha-mannosidase activity;GO:0005509//calcium ion binding","GO:0006486//protein glycosylation;GO:1904382//mannose trimming involved in glycoprotein ERAD pathway;GO:0006491//N-glycan processing;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0097466//ubiquitin-dependent glycoprotein ERAD pathway","K10086//ER degradation enhancer, mannosidase alpha-like 3","NP_079467.3//ER degradation-enhancing alpha-mannosidase-like protein 3 isoform 2 precursor [Homo sapiens];NP_001306889.1//ER degradation-enhancing alpha-mannosidase-like protein 3 isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[55793,3518,3.41,2.3,-0.568137878079797,0.0154976943614458,"*",0.00563676,"MINDY1","GO:0070062//extracellular exosome","GO:0036435//K48-linked polyubiquitin modification-dependent protein binding;GO:0004843//thiol-dependent ubiquitin-specific protease activity;GO:0016807//cysteine-type carboxypeptidase activity;GO:1990380//Lys48-specific deubiquitinase activity","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K01064//wingless-type MMTV integration site family, member 9;K12025//tripartite motif-containing protein 52","NP_001156730.1//ubiquitin carboxyl-terminal hydrolase MINDY-1 isoform 3 [Homo sapiens];NP_060849.2//ubiquitin carboxyl-terminal hydrolase MINDY-1 isoform 1 [Homo sapiens]","4;1//3;2//1"]
[10184,5061,13.84,9.34,-0.567349487927063,{"v":1.03602083141361E-12,"d":"1.04E-12"},"*",{"v":8.67134e-14,"d":"8.67E-14"},"LHFPL2","GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0031092//platelet alpha granule membrane","NA","GO:0046545//development of primary female sexual characteristics;GO:0002576//platelet degranulation;GO:1905516//positive regulation of fertilization;GO:0046546//development of primary male sexual characteristics;GO:0007338//single fertilization","NA","NP_005770.1//lipoma HMGIC fusion partner-like 2 protein [Homo sapiens]","2//1"]
[23221,5053,13.05,8.81,-0.566835882536833,{"v":8.9751265870923e-12,"d":"8.98E-12"},"*",{"v":8.09638e-13,"d":"8.10E-13"},"RHOBTB2","GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0007264//small GTPase mediated signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction","K07868//Rho-related BTB domain-containing protein 1/2","NP_001153509.1//rho-related BTB domain-containing protein 2 isoform 2 [Homo sapiens];XP_002756887.2//PREDICTED: rho-related BTB domain-containing protein 2 isoform X1 [Callithrix jacchus];NP_001153508.1//rho-related BTB domain-containing protein 2 isoform 1 [Homo sapiens]","1//3;2//1"]
[84656,3684,27.78,18.77,-0.565617949150518,{"v":1.5140933625498e-16,"d":"1.51E-16"},"*",{"v":9.5164e-18,"d":"9.52E-18"},"GLYR1","NA","NA","NA","K00020//3-hydroxyisobutyrate dehydrogenase [EC:1.1.1.31];K15195//AF4/FMR2 family member 3;K18121//glyoxylate/succinic semialdehyde reductase [EC:1.1.1.79 1.1.1.-]","XP_003815153.2//PREDICTED: putative oxidoreductase GLYR1 isoform X1 [Pan paniscus];XP_007982801.1//PREDICTED: LOW QUALITY PROTEIN: putative oxidoreductase GLYR1 [Chlorocebus sabaeus];XP_017361512.1//PREDICTED: putative oxidoreductase GLYR1 isoform X6 [Cebus capucinus imitator];XP_017361511.1//PREDICTED: putative oxidoreductase GLYR1 isoform X5 [Cebus capucinus imitator];XP_003815154.1//PREDICTED: putative oxidoreductase GLYR1 isoform X3 [Pan paniscus]","1//3;3//A2MP1"]
[91828,2591,1.05,0.71,-0.564498398161441,0.26250705779043,"*",0.1500862,"EXOC3L4","GO:0000145//exocyst","GO:0000149//SNARE binding","GO:0051601//exocyst localization;GO:0006887//exocytosis","K19988//exocyst complex component 3-like protein 2;K06110//exocyst complex component 3","XP_011535635.1//PREDICTED: exocyst complex component 3-like protein 4 isoform X3 [Homo sapiens]","1//3"]
[23252,6523,2.07,1.4,-0.564203940554359,0.00313331833663366,"*",0.000970752,"OTUD3","NA","NA","NA","K13717//OTU domain-containing protein 3 [EC:3.4.19.12]","XP_513073.6//PREDICTED: OTU domain-containing protein 3 isoform X1 [Pan troglodytes]","1//3"]
[90993,2741,0.99,0.67,-0.563267429621837,0.262478318239545,"*",0.1500862,"CREB3L1","GO:0016020//membrane;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0003682//chromatin binding;GO:0035497//cAMP response element binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0046332//SMAD binding;GO:0003700//DNA binding transcription factor activity;GO:0044212//transcription regulatory region DNA binding","GO:0001649//osteoblast differentiation;GO:0032967//positive regulation of collagen biosynthetic process;GO:1990440//positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress;GO:0070278//extracellular matrix constituent secretion;GO:0007275//multicellular organism development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0030968//endoplasmic reticulum unfolded protein response;GO:1902236//negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway","K09048//cyclic AMP-responsive element-binding protein 3","NP_443086.1//cyclic AMP-responsive element-binding protein 3-like protein 1 [Homo sapiens]","3//A2MP1"]
[85460,6936,1.18,0.8,-0.560714954474479,0.026604700860319,"*",0.01033776,"ZNF518B","GO:0005634//nucleus","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003676//nucleic acid binding","GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","NP_444270.2//zinc finger protein 518B [Homo sapiens]","2//1"]
[57489,4323,7.05,4.78,-0.560612639305407,{"v":6.10467969836503e-06,"d":"6.10E-06"},"*",{"v":1.145344E-6,"d":"1.15E-06"},"ODF2L","GO:0005813//centrosome","NA","NA","K16479//outer dense fiber protein 2","NP_001171694.1//outer dense fiber protein 2-like isoform c [Homo sapiens];NP_001171695.1//outer dense fiber protein 2-like isoform d [Homo sapiens];NP_001007023.2//outer dense fiber protein 2-like isoform b [Homo sapiens];NP_065780.2//outer dense fiber protein 2-like isoform a [Homo sapiens]","1//3;2//1"]
[2009,4479,11.16,7.57,-0.559971821843456,{"v":4.06300848648649e-09,"d":"4.06E-09"},"*",{"v":4.89372e-10,"d":"4.89E-10"},"EML1","NA","NA","NA","K18595//echinoderm microtubule-associated protein-like 1/2","XP_001367603.1//PREDICTED: echinoderm microtubule-associated protein-like 1 isoform X4 [Monodelphis domestica];XP_001367643.1//PREDICTED: echinoderm microtubule-associated protein-like 1 isoform X7 [Monodelphis domestica]","1//3;2//1"]
[3087,1772,14.86,10.09,-0.558507941432239,{"v":3.67539570672098e-05,"d":"3.68E-05"},"*",{"v":7.90806e-06,"d":"7.91E-06"},"HHEX","GO:0005634//nucleus;GO:0032993//protein-DNA complex;GO:0005737//cytoplasm","GO:0071837//HMG box domain binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0070491//repressing transcription factor binding;GO:0044212//transcription regulatory region DNA binding;GO:0042803//protein homodimerization activity;GO:0001227//transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0008190//eukaryotic initiation factor 4E binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0017025//TBP-class protein binding;GO:0043565//sequence-specific DNA binding;GO:0008134//transcription factor binding;GO:0008301//DNA binding, bending","GO:0042127//regulation of cell proliferation;GO:0048853//forebrain morphogenesis;GO:0030878//thyroid gland development;GO:0016973//poly(A)+ mRNA export from nucleus;GO:0001570//vasculogenesis;GO:0009611//response to wounding;GO:0045892//negative regulation of transcription, DNA-templated;GO:0007492//endoderm development;GO:0030154//cell differentiation;GO:0060431//primary lung bud formation;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0035264//multicellular organism growth;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0016055//Wnt signaling pathway;GO:0007219//Notch signaling pathway;GO:0071103//DNA conformation change;GO:0009952//anterior/posterior pattern specification;GO:0006406//mRNA export from nucleus;GO:0010944//negative regulation of transcription by competitive promoter binding;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0090009//primitive streak formation;GO:0008283//cell proliferation;GO:0061017//hepatoblast differentiation;GO:0030948//negative regulation of vascular endothelial growth factor receptor signaling pathway;GO:0030183//B cell differentiation;GO:0070365//hepatocyte differentiation;GO:0016525//negative regulation of angiogenesis;GO:0043434//response to peptide hormone;GO:0006351//transcription, DNA-templated;GO:0001701//in utero embryonic development;GO:0035050//embryonic heart tube development;GO:0002573//myeloid leukocyte differentiation;GO:0031016//pancreas development;GO:0030177//positive regulation of Wnt signaling pathway;GO:0061010//gall bladder development;GO:0010621//negative regulation of transcription by transcription factor localization;GO:0061011//hepatic duct development;GO:0034504//protein localization to nucleus;GO:0022027//interkinetic nuclear migration","K08024//homeobox protein HEX","XP_003783831.1//PREDICTED: hematopoietically-expressed homeobox protein HHEX [Otolemur garnettii]",4]
[586,9303,1.62,1.1,-0.558490289359965,0.00202064538108279,"*",0.000600476,"BCAT1","GO:0005829//cytosol;GO:0005739//mitochondrion","GO:0052654//L-leucine transaminase activity;GO:0004084//branched-chain-amino-acid transaminase activity;GO:0052656//L-isoleucine transaminase activity;GO:0042802//identical protein binding;GO:0052655//L-valine transaminase activity","GO:0009099//valine biosynthetic process;GO:0009098//leucine biosynthetic process;GO:0009083//branched-chain amino acid catabolic process;GO:0008283//cell proliferation;GO:0000082//G1/S transition of mitotic cell cycle;GO:0009082//branched-chain amino acid biosynthetic process","K00826//branched-chain amino acid aminotransferase [EC:2.6.1.42]","NP_001171565.1//branched-chain-amino-acid aminotransferase, cytosolic isoform 5 [Homo sapiens];XP_016875257.1//PREDICTED: branched-chain-amino-acid aminotransferase, cytosolic isoform X1 [Homo sapiens];XP_001143074.3//PREDICTED: branched-chain-amino-acid aminotransferase, cytosolic isoform X1 [Pan troglodytes]","6;1//3"]
[643853,3714,0.5,0.34,-0.556393348524385,0.399180063829787,"*",0.25839,"TMPPE","GO:0016021//integral component of membrane","GO:0046872//metal ion binding;GO:0016787//hydrolase activity","NA","K10457//kelch-like protein 20;K12309//beta-galactosidase [EC:3.2.1.23]","NP_001034859.2//transmembrane protein with metallophosphoesterase domain isoform 1 [Homo sapiens]","1//3;2//1"]
[5066,5130,3.1,2.11,-0.555025216567053,0.00167849560908701,"*",0.000490288,"PAM","GO:0000793//condensed chromosome;GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0030667//secretory granule membrane;GO:0000790//nuclear chromatin;GO:0005802//trans-Golgi network;GO:0048471//perinuclear region of cytoplasm;GO:0043204//perikaryon;GO:0043005//neuron projection;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004504//peptidylglycine monooxygenase activity;GO:0031418//L-ascorbic acid binding;GO:0019901//protein kinase binding;GO:0004598//peptidylamidoglycolate lyase activity;GO:0005509//calcium ion binding;GO:0005507//copper ion binding;GO:0003682//chromatin binding;GO:0008270//zinc ion binding","GO:0018032//protein amidation;GO:0007595//lactation;GO:0060135//maternal process involved in female pregnancy;GO:0009404//toxin metabolic process;GO:0051260//protein homooligomerization;GO:0032956//regulation of actin cytoskeleton organization;GO:0007076//mitotic chromosome condensation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0032355//response to estradiol;GO:0051384//response to glucocorticoid;GO:0001519//peptide amidation;GO:0042476//odontogenesis;GO:0022602//ovulation cycle process;GO:0042493//response to drug;GO:0009268//response to pH;GO:0007507//heart development;GO:0007417//central nervous system development;GO:0001676//long-chain fatty acid metabolic process;GO:0046688//response to copper ion;GO:0001666//response to hypoxia;GO:0060173//limb development;GO:0050708//regulation of protein secretion","K00504//peptidylglycine monooxygenase [EC:1.14.17.3];K18200//peptidylamidoglycolate lyase [EC:4.3.2.5]","NP_620121.1//peptidyl-glycine alpha-amidating monooxygenase isoform b precursor [Homo sapiens];NP_620177.1//peptidyl-glycine alpha-amidating monooxygenase isoform d precursor [Homo sapiens];NP_000910.2//peptidyl-glycine alpha-amidating monooxygenase isoform a precursor [Homo sapiens];NP_001170777.1//peptidyl-glycine alpha-amidating monooxygenase isoform e preproprotein [Homo sapiens];NP_620176.1//peptidyl-glycine alpha-amidating monooxygenase isoform c precursor [Homo sapiens];NP_001306872.1//peptidyl-glycine alpha-amidating monooxygenase isoform f precursor [Homo sapiens]","1//3;3//A2MP1;2//1"]
[54813,6577,1.19,0.81,-0.554967760423319,0.0336923418397626,"*",0.0135052,"KLHL28","GO:0031463//Cul3-RING ubiquitin ligase complex","NA","GO:0016567//protein ubiquitination","K10464//kelch-like protein 28","NP_001295041.1//kelch-like protein 28 isoform 1 [Homo sapiens]","4;1//3"]
[221322,5134,0.69,0.47,-0.553935605100532,0.200602963412633,"*",0.1071582,"TBC1D32","GO:0005929//cilium;GO:0005737//cytoplasm","NA","GO:0060831//smoothened signaling pathway involved in dorsal/ventral neural tube patterning;GO:0003406//retinal pigment epithelium development;GO:0007368//determination of left/right symmetry;GO:0007507//heart development;GO:1905515//non-motile cilium assembly;GO:0061512//protein localization to cilium;GO:0002088//lens development in camera-type eye;GO:0042733//embryonic digit morphogenesis","K12581//CCR4-NOT transcription complex subunit 7/8;K01368//cathepsin S [EC:3.4.22.27];K04135//adrenergic receptor alpha-1A;K20636//Rho GTPase-activating protein 12/27;K10477//BTB/POZ domain-containing protein 1/2","NP_689943.4//protein broad-minded [Homo sapiens]",5]
[57609,8715,5.43,3.7,-0.553426927288049,{"v":1.3049425542192E-8,"d":"1.30E-08"},"*",{"v":1.684482E-9,"d":"1.68E-09"},"DIP2B","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0003824//catalytic activity","GO:0008152//metabolic process","K05637//laminin, alpha 1/2;K05747//Wiskott-Aldrich syndrome protein;K06274//vasodilator-stimulated phosphoprotein","XP_004429071.1//PREDICTED: disco-interacting protein 2 homolog B isoform X2 [Ceratotherium simum simum]","2//1"]
[84340,3258,14.04,9.57,-0.552952105818535,{"v":2.5610166895902e-08,"d":"2.56E-08"},"*",{"v":3.40368E-9,"d":"3.40E-09"},"GFM2","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0003746//translation elongation factor activity;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0032543//mitochondrial translation;GO:0070126//mitochondrial translational termination;GO:0032790//ribosome disassembly","K02355//elongation factor G","NP_001268231.1//ribosome-releasing factor 2, mitochondrial isoform 4 [Homo sapiens];NP_733781.1//ribosome-releasing factor 2, mitochondrial isoform 3 [Homo sapiens];NP_733792.1//ribosome-releasing factor 2, mitochondrial isoform 2 [Homo sapiens]","4;1//3;2//1"]
[10746,10870,3.59,2.45,-0.551202094820481,{"v":3.87084891011236E-7,"d":"3.87E-07"},"*",{"v":6.03866e-08,"d":"6.04E-08"},"MAP3K2","GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0004709//MAP kinase kinase kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0019901//protein kinase binding","GO:0007346//regulation of mitotic cell cycle;GO:0071260//cellular response to mechanical stimulus;GO:0000187//activation of MAPK activity;GO:0006468//protein phosphorylation;GO:0042981//regulation of apoptotic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0007257//activation of JUN kinase activity","K04420//mitogen-activated protein kinase kinase kinase 2 [EC:2.7.11.25]","XP_007122724.1//PREDICTED: LOW QUALITY PROTEIN: mitogen-activated protein kinase kinase kinase 2 [Physeter catodon]",4]
[10905,8606,2.08,1.42,-0.55069259863641,0.000875606497737557,"*",0.00024228,"MAN1A2","GO:0070062//extracellular exosome;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0004571//mannosyl-oligosaccharide 1,2-alpha-mannosidase activity;GO:0005509//calcium ion binding","GO:0007585//respiratory gaseous exchange;GO:0009100//glycoprotein metabolic process;GO:0008152//metabolic process;GO:0048286//lung alveolus development","K01230//mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]","XP_003933576.1//PREDICTED: mannosyl-oligosaccharide 1,2-alpha-mannosidase IB [Saimiri boliviensis boliviensis]",4]
[6646,6933,8.87,6.06,-0.549616310828113,{"v":8.00697761012658e-11,"d":"8.01E-11"},"*",{"v":7.91976e-12,"d":"7.92E-12"},"SOAT1","GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0004772//sterol O-acyltransferase activity;GO:0015485//cholesterol binding;GO:0000062//fatty-acyl-CoA binding;GO:0034736//cholesterol O-acyltransferase activity","GO:0034383//low-density lipoprotein particle clearance;GO:0042986//positive regulation of amyloid precursor protein biosynthetic process;GO:0010878//cholesterol storage;GO:0008203//cholesterol metabolic process;GO:0034435//cholesterol esterification;GO:0033344//cholesterol efflux;GO:0034379//very-low-density lipoprotein particle assembly;GO:0010742//macrophage derived foam cell differentiation;GO:0042632//cholesterol homeostasis","K00637//sterol O-acyltransferase [EC:2.3.1.26]","NP_001239440.1//sterol O-acyltransferase 1 isoform 2 [Homo sapiens];NP_003092.4//sterol O-acyltransferase 1 isoform 1 [Homo sapiens]","1//3;5"]
[3720,5981,3.35,2.29,-0.548813497248191,{"v":9.32441299425759e-05,"d":"9.32E-05"},"*",{"v":2.13468E-5,"d":"2.13E-05"},"JARID2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0035097//histone methyltransferase complex;GO:0005739//mitochondrion;GO:0035098//ESC/E(Z) complex","GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0008134//transcription factor binding;GO:0001227//transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0060044//negative regulation of cardiac muscle cell proliferation;GO:0001889//liver development;GO:0048538//thymus development;GO:0006351//transcription, DNA-templated;GO:0051574//positive regulation of histone H3-K9 methylation;GO:0007417//central nervous system development;GO:0048863//stem cell differentiation;GO:0010614//negative regulation of cardiac muscle hypertrophy;GO:1990830//cellular response to leukemia inhibitory factor;GO:0048536//spleen development;GO:0016569//covalent chromatin modification;GO:0045814//negative regulation of gene expression, epigenetic;GO:0031061//negative regulation of histone methylation;GO:0008285//negative regulation of cell proliferation","K11478//protein Jumonji","NP_004964.2//protein Jumonji isoform 1 [Homo sapiens];XP_016866322.1//PREDICTED: protein Jumonji isoform X2 [Homo sapiens]","1//3;3//A2MP1"]
[146198,4655,3.48,2.38,-0.548125732540785,0.000551408180541814,"*",1.465336E-4,"ZFP90","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0043392//negative regulation of DNA binding;GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein;K09230//SCAN domain-containing zinc finger protein","XP_012926981.1//zinc finger protein 90 homolog isoform X2 [Heterocephalus glaber];NP_001292133.1//zinc finger protein 90 homolog isoform 2 [Homo sapiens];XP_003998236.1//PREDICTED: zinc finger protein 90 homolog isoform X2 [Felis catus]","1//3;3//A2MP1"]
[100506012,1257,0.19,0.13,-0.547487795302493,0.782151852820003,"*",0.689316,"PPP5D1","NA","NA","NA","K04460//serine/threonine-protein phosphatase 5 [EC:3.1.3.16]","NP_001192210.1//protein PPP5D1 [Homo sapiens]","1//3"]
[81846,7447,3.96,2.71,-0.547207578725738,{"v":1.4027947892575E-5,"d":"1.40E-05"},"*",{"v":2.77942e-06,"d":"2.78E-06"},"SBF2","GO:0005774//vacuolar membrane;GO:0016020//membrane;GO:0005829//cytosol","GO:0019902//phosphatase binding;GO:0017112//Rab guanyl-nucleotide exchange factor activity;GO:0042803//protein homodimerization activity;GO:0019208//phosphatase regulator activity;GO:0035091//phosphatidylinositol binding","GO:0042552//myelination;GO:0043087//regulation of GTPase activity;GO:0051262//protein tetramerization;GO:0061024//membrane organization","K18061//myotubularin-related protein 5/13","XP_003818195.1//PREDICTED: myotubularin-related protein 13 isoform X3 [Pan paniscus]","3//A2MP1"]
[23483,1980,2.98,2.04,-0.546743178490666,0.0862596,"*",0.0394686,"TGDS","NA","GO:0008460//dTDP-glucose 4,6-dehydratase activity","NA","K01710//dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]","XP_006211070.1//PREDICTED: dTDP-D-glucose 4,6-dehydratase [Vicugna pacos];NP_055120.1//dTDP-D-glucose 4,6-dehydratase isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[284353,4687,0.54,0.37,-0.545434136534519,0.241301762683905,"*",0.1355302,"NKPD1","NA","NA","NA","K12460//ankyrin repeat-rich membrane spanning protein;K18167//succinate dehydrogenase assembly factor 1","XP_011525101.1//PREDICTED: NTPase KAP family P-loop domain-containing protein 1 isoform X1 [Homo sapiens]","3//A2MP1"]
[79879,1343,1.94,1.33,-0.544630406685938,0.304600263164611,"*",0.1793202,"CCDC134","GO:0016020//membrane;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005576//extracellular region","NA","NA","K19501//anoctamin-7","XP_011710499.1//PREDICTED: coiled-coil domain-containing protein 134 isoform X3 [Macaca nemestrina];XP_005567186.1//PREDICTED: coiled-coil domain-containing protein 134 isoform X1 [Macaca fascicularis]","1//3;3//A2MP1"]
[7046,6449,6.18,4.24,-0.543542573341175,{"v":1.66902992648923E-7,"d":"1.67E-07"},"*",{"v":2.47314E-8,"d":"2.47E-08"},"TGFBR1","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005622//intracellular;GO:0043235//receptor complex;GO:0005768//endosome;GO:0009986//cell surface;GO:0045121//membrane raft;GO:0005623//cell;GO:0005923//bicellular tight junction;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005025//transforming growth factor beta receptor activity, type I;GO:0005057//signal transducer activity, downstream of receptor;GO:0005524//ATP binding;GO:0005114//type II transforming growth factor beta receptor binding;GO:0046872//metal ion binding;GO:0004672//protein kinase activity;GO:0070411//I-SMAD binding;GO:0004702//signal transducer, downstream of receptor, with serine/threonine kinase activity;GO:0004675//transmembrane receptor protein serine/threonine kinase activity;GO:0050431//transforming growth factor beta binding","GO:1905075//positive regulation of occluding junction disassembly;GO:0060412//ventricular septum morphogenesis;GO:0030335//positive regulation of cell migration;GO:0060317//cardiac epithelial to mesenchymal transition;GO:0010717//regulation of epithelial to mesenchymal transition;GO:0030199//collagen fibril organization;GO:0008354//germ cell migration;GO:0008584//male gonad development;GO:0060978//angiogenesis involved in coronary vascular morphogenesis;GO:0009791//post-embryonic development;GO:0003223//ventricular compact myocardium morphogenesis;GO:0001837//epithelial to mesenchymal transition;GO:0002088//lens development in camera-type eye;GO:0000186//activation of MAPKK activity;GO:0031396//regulation of protein ubiquitination;GO:0001937//negative regulation of endothelial cell proliferation;GO:0043393//regulation of protein binding;GO:0043542//endothelial cell migration;GO:0060017//parathyroid gland development;GO:0007507//heart development;GO:0060037//pharyngeal system development;GO:0032924//activin receptor signaling pathway;GO:0010628//positive regulation of gene expression;GO:2001235//positive regulation of apoptotic signaling pathway;GO:0018107//peptidyl-threonine phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0048663//neuron fate commitment;GO:1905223//epicardium morphogenesis;GO:0003222//ventricular trabecula myocardium morphogenesis;GO:0009952//anterior/posterior pattern specification;GO:0051897//positive regulation of protein kinase B signaling;GO:0010468//regulation of gene expression;GO:0001822//kidney development;GO:0030307//positive regulation of cell growth;GO:0035556//intracellular signal transduction;GO:0045893//positive regulation of transcription, DNA-templated;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0001824//blastocyst development;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:1905007//positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation;GO:0001938//positive regulation of endothelial cell proliferation;GO:0060021//palate development;GO:0060043//regulation of cardiac muscle cell proliferation;GO:0070723//response to cholesterol;GO:0051491//positive regulation of filopodium assembly;GO:0060982//coronary artery morphogenesis;GO:0060391//positive regulation of SMAD protein import into nucleus;GO:0048538//thymus development;GO:0051496//positive regulation of stress fiber assembly;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0032331//negative regulation of chondrocyte differentiation;GO:0060389//pathway-restricted SMAD protein phosphorylation;GO:0042118//endothelial cell activation;GO:0008284//positive regulation of cell proliferation;GO:0048762//mesenchymal cell differentiation","K04674//TGF-beta receptor type-1 [EC:2.7.11.30]","NP_001293139.1//TGF-beta receptor type-1 isoform 3 precursor [Homo sapiens];XP_007966794.1//PREDICTED: TGF-beta receptor type-1 isoform X3 [Chlorocebus sabaeus];NP_004603.1//TGF-beta receptor type-1 isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1;2//1"]
[25942,6674,15.94,10.95,-0.541720759501936,{"v":1.36255447939262E-17,"d":"1.36E-17"},"*",{"v":7.8645e-19,"d":"7.86E-19"},"SIN3A","GO:0017053//transcriptional repressor complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005667//transcription factor complex;GO:0016580//Sin3 complex;GO:0000776//kinetochore","GO:0003723//RNA binding;GO:0001103//RNA polymerase II repressing transcription factor binding;GO:0033558//protein deacetylase activity;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0001106//RNA polymerase II transcription corepressor activity;GO:0003682//chromatin binding;GO:0001102//RNA polymerase II activating transcription factor binding;GO:0003700//DNA binding transcription factor activity;GO:0032403//protein complex binding","GO:2000678//negative regulation of transcription regulatory region DNA binding;GO:0042754//negative regulation of circadian rhythm;GO:0002244//hematopoietic progenitor cell differentiation;GO:0006260//DNA replication;GO:0002218//activation of innate immune response;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0031937//positive regulation of chromatin silencing;GO:0043619//regulation of transcription from RNA polymerase II promoter in response to oxidative stress;GO:0019216//regulation of lipid metabolic process;GO:1901675//negative regulation of histone H3-K27 acetylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0001701//in utero embryonic development;GO:0043066//negative regulation of apoptotic process;GO:0048511//rhythmic process;GO:0051595//response to methylglyoxal;GO:0045652//regulation of megakaryocyte differentiation;GO:0007568//aging;GO:0071333//cellular response to glucose stimulus;GO:1903351//cellular response to dopamine;GO:0010817//regulation of hormone levels;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0010971//positive regulation of G2/M transition of mitotic cell cycle;GO:0034613//cellular protein localization;GO:1900181//negative regulation of protein localization to nucleus;GO:0016575//histone deacetylation;GO:0002230//positive regulation of defense response to virus by host;GO:0006476//protein deacetylation","K11644//paired amphipathic helix protein Sin3a","XP_016782697.1//PREDICTED: paired amphipathic helix protein Sin3a isoform X1 [Pan troglodytes]","1//3;2//1"]
[56833,2973,0.16,0.11,-0.540568381362703,0.670110212105063,"*",0.551014,"SLAMF8","GO:0016021//integral component of membrane","NA","NA","K16853//SLAM family member 8","NP_064510.1//SLAM family member 8 isoform 1 precursor [Homo sapiens];NP_001317670.1//SLAM family member 8 isoform 2 [Homo sapiens]","1//3;2//1"]
[286006,1480,0.16,0.11,-0.540568381362703,0.781541187025339,"*",0.689316,"LSMEM1","GO:0005829//cytosol;GO:0016021//integral component of membrane","NA","NA","NA","NP_872403.1//leucine-rich single-pass membrane protein 1 [Homo sapiens];XP_011811322.1//PREDICTED: leucine-rich single-pass membrane protein 1 isoform X1 [Colobus angolensis palliatus]","1//3;2//1"]
[64770,4211,8.94,6.15,-0.539688420956715,{"v":8.97332763774734e-07,"d":"8.97E-07"},"*",{"v":1.476268e-07,"d":"1.48E-07"},"CCDC14","GO:0005813//centrosome;GO:0034451//centriolar satellite","NA","GO:0021762//substantia nigra development;GO:0071539//protein localization to centrosome","K16541//coiled-coil domain-containing protein 14","XP_005247767.1//PREDICTED: coiled-coil domain-containing protein 14 isoform X1 [Homo sapiens];XP_009444589.2//PREDICTED: coiled-coil domain-containing protein 14 isoform X2 [Pan troglodytes]","4;1//3"]
[631,2073,2.95,2.03,-0.539235227064028,0.0756867906053404,"*",0.0338918,"BFSP1","GO:0005938//cell cortex;GO:0005882//intermediate filament;GO:0005737//cytoplasm;GO:0005886//plasma membrane","GO:0005212//structural constituent of eye lens;GO:0005200//structural constituent of cytoskeleton","GO:0048469//cell maturation;GO:0070307//lens fiber cell development","K10378//filensin","NP_001265536.1//filensin isoform 4 [Homo sapiens];NP_001186.1//filensin isoform 1 [Homo sapiens]","4;1//3"]
[10052,7643,6.13,4.22,-0.538644074983596,{"v":3.42479029834254E-8,"d":"3.42E-08"},"*",{"v":4.65672E-9,"d":"4.66E-09"},"GJC1","GO:0005921//gap junction;GO:0005922//connexin complex;GO:0016021//integral component of membrane;GO:0014704//intercalated disc;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane","GO:0005216//ion channel activity;GO:0086020//gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling;GO:0086077//gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling","GO:0006810//transport;GO:0007043//cell-cell junction assembly;GO:0086053//AV node cell to bundle of His cell communication by electrical coupling;GO:0006936//muscle contraction;GO:0048738//cardiac muscle tissue development;GO:0007154//cell communication;GO:0007601//visual perception;GO:0016264//gap junction assembly;GO:0086014//atrial cardiac muscle cell action potential;GO:0007268//chemical synaptic transmission;GO:0001570//vasculogenesis;GO:0086021//SA node cell to atrial cardiac muscle cell communication by electrical coupling;GO:0048468//cell development","K07616//gap junction gamma-1 protein","NP_005488.2//gap junction gamma-1 protein [Homo sapiens]","1//3;3//A2MP1"]
[25898,4447,1.51,1.04,-0.537965021183987,0.0685483877806195,"*",0.0302018,"RCHY1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000151//ubiquitin ligase complex;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0005737//cytoplasm","GO:0002039//p53 binding;GO:0008270//zinc ion binding;GO:0005102//receptor binding;GO:0042803//protein homodimerization activity;GO:0004842//ubiquitin-protein transferase activity","GO:0070987//error-free translesion synthesis;GO:0016567//protein ubiquitination;GO:0051865//protein autoubiquitination;GO:0031398//positive regulation of protein ubiquitination;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process","K10144//RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27]","NP_001265465.1//RING finger and CHY zinc finger domain-containing protein 1 isoform 4 [Homo sapiens];XP_017732079.1//PREDICTED: RING finger and CHY zinc finger domain-containing protein 1 isoform X1 [Rhinopithecus bieti];NP_001009922.1//RING finger and CHY zinc finger domain-containing protein 1 isoform 3 [Homo sapiens];NP_001265467.1//RING finger and CHY zinc finger domain-containing protein 1 isoform 6 [Homo sapiens];NP_001265466.1//RING finger and CHY zinc finger domain-containing protein 1 isoform 5 [Homo sapiens];BAD92309.1//RING finger and CHY zinc finger domain containing protein 1 variant, partial [Homo sapiens]","1//3;3//A2MP1;2//1"]
[5205,6169,3.41,2.35,-0.537110982459173,4.51623524705882E-4,"*",1.177546E-4,"ATP8B1","GO:0005783//endoplasmic reticulum;GO:0016324//apical plasma membrane;GO:0031526//brush border membrane;GO:0005887//integral component of plasma membrane;GO:0005794//Golgi apparatus;GO:0032420//stereocilium;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0000287//magnesium ion binding;GO:1901612//cardiolipin binding;GO:0005524//ATP binding;GO:0004012//phospholipid-translocating ATPase activity;GO:0015247//aminophospholipid transmembrane transporter activity","GO:0045892//negative regulation of transcription, DNA-templated;GO:0034220//ion transmembrane transport;GO:0007030//Golgi organization;GO:0015721//bile acid and bile salt transport;GO:0021650//vestibulocochlear nerve formation;GO:0045332//phospholipid translocation;GO:0032534//regulation of microvillus assembly;GO:0007605//sensory perception of sound;GO:0060119//inner ear receptor cell development;GO:0008206//bile acid metabolic process;GO:0006855//drug transmembrane transport","K01530//phospholipid-translocating ATPase [EC:3.6.3.1]","NP_005594.1//phospholipid-transporting ATPase IC [Homo sapiens]",5]
[22834,11434,2.48,1.71,-0.536343795500977,{"v":3.79645178403483e-05,"d":"3.80E-05"},"*",{"v":8.18754e-06,"d":"8.19E-06"},"ZNF652","NA","GO:0003676//nucleic acid binding","NA","K09228//KRAB domain-containing zinc finger protein","XP_003996761.1//PREDICTED: zinc finger protein 652 [Felis catus]","1//3;2//1"]
[8793,3569,13.35,9.21,-0.535566680483581,{"v":4.1882112866242E-8,"d":"4.19E-08"},"*",{"v":5.76292e-09,"d":"5.76E-09"},"TNFRSF10D","GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane","GO:0045569//TRAIL binding;GO:0004888//transmembrane signaling receptor activity;GO:0005031//tumor necrosis factor-activated receptor activity","GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007165//signal transduction;GO:0050900//leukocyte migration;GO:0097190//apoptotic signaling pathway;GO:0042127//regulation of cell proliferation;GO:0032496//response to lipopolysaccharide;GO:0043066//negative regulation of apoptotic process;GO:0006954//inflammatory response;GO:0007275//multicellular organism development;GO:0006955//immune response;GO:0042981//regulation of apoptotic process","K04722//tumor necrosis factor receptor superfamily member 10","NP_003831.2//tumor necrosis factor receptor superfamily member 10D precursor [Homo sapiens]",4]
[4361,5150,3.97,2.74,-0.534963114182431,0.000512717614529915,"*",1.351926E-4,"MRE11","GO:0035861//site of double-strand break;GO:0016605//PML body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000784//nuclear chromosome, telomeric region;GO:0030870//Mre11 complex;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0042802//identical protein binding;GO:0000014//single-stranded DNA endodeoxyribonuclease activity;GO:0003690//double-stranded DNA binding;GO:0004518//nuclease activity;GO:0045296//cadherin binding;GO:0004520//endodeoxyribonuclease activity;GO:0008408//3'-5' exonuclease activity;GO:0008022//protein C-terminus binding;GO:0004519//endonuclease activity;GO:0030145//manganese ion binding","GO:0032481//positive regulation of type I interferon production;GO:0007095//mitotic G2 DNA damage checkpoint;GO:0031860//telomeric 3' overhang formation;GO:0006260//DNA replication;GO:0031954//positive regulation of protein autophosphorylation;GO:0032508//DNA duplex unwinding;GO:0006302//double-strand break repair;GO:0031573//intra-S DNA damage checkpoint;GO:0007131//reciprocal meiotic recombination;GO:0008283//cell proliferation;GO:0000731//DNA synthesis involved in DNA repair;GO:0051321//meiotic cell cycle;GO:0007004//telomere maintenance via telomerase;GO:0006974//cellular response to DNA damage stimulus;GO:0007129//synapsis;GO:0000732//strand displacement;GO:0006281//DNA repair;GO:0043066//negative regulation of apoptotic process;GO:0016032//viral process;GO:0032206//positive regulation of telomere maintenance;GO:1901796//regulation of signal transduction by p53 class mediator;GO:0000729//DNA double-strand break processing;GO:0000019//regulation of mitotic recombination;GO:0007062//sister chromatid cohesion;GO:0032876//negative regulation of DNA endoreduplication;GO:0033674//positive regulation of kinase activity;GO:0000724//double-strand break repair via homologous recombination;GO:0006310//DNA recombination;GO:0006303//double-strand break repair via nonhomologous end joining","K10865//double-strand break repair protein MRE11","XP_016777317.1//PREDICTED: double-strand break repair protein MRE11A isoform X1 [Pan troglodytes];NP_005581.2//double-strand break repair protein MRE11 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[200539,2591,1.97,1.36,-0.534588978206037,0.11733321610247,"*",0.0561986,"ANKRD23","GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0030016//myofibril;GO:0014704//intercalated disc","GO:0031432//titin binding","GO:0009612//response to mechanical stimulus","K21438//ankyrin repeat domain-containing protein 23","NP_659431.5//ankyrin repeat domain-containing protein 23 [Homo sapiens]",7]
[6654,8331,6.53,4.51,-0.53395555829105,{"v":3.57695750261233e-09,"d":"3.58E-09"},"*",{"v":4.2859e-10,"d":"4.29E-10"},"SOS1","NA","NA","NA","K03099//son of sevenless","DAA24733.1//TPA: son of sevenless homolog 1 [Bos taurus]","3//A2MP1"]
[255967,5643,2.59,1.79,-0.532992510422297,0.0042089775916519,"*",1.338262E-3,"PAN3","NA","NA","NA","K12572//PAB-dependent poly(A)-specific ribonuclease subunit 3","XP_003913764.2//PAB-dependent poly(A)-specific ribonuclease subunit PAN3 isoform X1 [Papio anubis]",7]
[54877,5559,2.53,1.75,-0.531782462861982,0.00495619849359721,"*",1.599114E-3,"ZCCHC2","GO:0005737//cytoplasm","GO:0008270//zinc ion binding;GO:0035091//phosphatidylinositol binding;GO:0003676//nucleic acid binding","NA","K16628//collagen, type VII, alpha;K03129//transcription initiation factor TFIID subunit 4","NP_060212.4//zinc finger CCHC domain-containing protein 2 [Homo sapiens]",5]
[51701,3555,4.42,3.06,-0.53051471669878,0.00293872888879854,"*",0.000904946,"NLK","GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005737//cytoplasm","GO:0000287//magnesium ion binding;GO:0005524//ATP binding;GO:0031625//ubiquitin protein ligase binding;GO:0042169//SH2 domain binding;GO:0004674//protein serine/threonine kinase activity;GO:0004672//protein kinase activity;GO:0004707//MAP kinase activity;GO:0008134//transcription factor binding","GO:0010468//regulation of gene expression;GO:0006355//regulation of transcription, DNA-templated;GO:0030178//negative regulation of Wnt signaling pathway;GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction;GO:0006351//transcription, DNA-templated;GO:0046777//protein autophosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0042501//serine phosphorylation of STAT protein;GO:0007223//Wnt signaling pathway, calcium modulating pathway;GO:0016055//Wnt signaling pathway;GO:0050821//protein stabilization","K04468//nemo like kinase [EC:2.7.11.24]","NP_057315.3//serine/threonine-protein kinase NLK [Homo sapiens]",4]
[3631,6427,4.81,3.33,-0.53051471669878,{"v":3.63114952725153e-05,"d":"3.63E-05"},"*",{"v":7.79922e-06,"d":"7.80E-06"},"INPP4A","GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0017161//inositol-1,3,4-trisphosphate 4-phosphatase activity;GO:0034597//phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity;GO:0052828//inositol-3,4-bisphosphate 4-phosphatase activity;GO:0016316//phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity","GO:0007165//signal transduction;GO:0043647//inositol phosphate metabolic process;GO:0006661//phosphatidylinositol biosynthetic process","K01109//inositol polyphosphate-4-phosphatase [EC:3.1.3.66]","NP_001557.1//type I inositol 3,4-bisphosphate 4-phosphatase isoform b [Homo sapiens];NP_001127696.1//type I inositol 3,4-bisphosphate 4-phosphatase isoform d [Homo sapiens];NP_004018.1//type I inositol 3,4-bisphosphate 4-phosphatase isoform a [Homo sapiens];NP_001338357.1//type I inositol 3,4-bisphosphate 4-phosphatase isoform g [Homo sapiens];NP_001127697.1//type I inositol 3,4-bisphosphate 4-phosphatase isoform c [Homo sapiens];NP_001338353.1//type I inositol 3,4-bisphosphate 4-phosphatase isoform e [Homo sapiens];NP_001338355.1//type I inositol 3,4-bisphosphate 4-phosphatase isoform f [Homo sapiens];NP_001338358.1//type I inositol 3,4-bisphosphate 4-phosphatase isoform h [Homo sapiens]","1//3;2//1"]
[5151,3876,25.61,17.73,-0.53051471669878,{"v":5.873868e-17,"d":"5.87E-17"},"*",{"v":3.57786e-18,"d":"3.58E-18"},"PDE8A","GO:0070062//extracellular exosome;GO:0005829//cytosol","GO:0046872//metal ion binding;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0019900//kinase binding;GO:0004115//3',5'-cyclic-AMP phosphodiesterase activity","GO:1903206//negative regulation of hydrogen peroxide-induced cell death;GO:0009187//cyclic nucleotide metabolic process;GO:0006198//cAMP catabolic process;GO:0007165//signal transduction;GO:0006355//regulation of transcription, DNA-templated;GO:0001934//positive regulation of protein phosphorylation;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0060548//negative regulation of cell death;GO:0071364//cellular response to epidermal growth factor stimulus","K18437//high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:3.1.4.53]","NP_002596.1//high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform 1 [Homo sapiens];NP_775656.1//high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform 2 [Homo sapiens]","1//3;2//1"]
[8505,3645,8.04,5.57,-0.529518173838897,{"v":2.4794504953868E-6,"d":"2.48E-06"},"*",{"v":4.37404e-07,"d":"4.37E-07"},"PARG","GO:0005759//mitochondrial matrix;GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0004649//poly(ADP-ribose) glycohydrolase activity","GO:1990966//ATP generation from poly-ADP-D-ribose;GO:0005975//carbohydrate metabolic process","K07759//poly(ADP-ribose) glycohydrolase [EC:3.2.1.143]","NP_001290415.1//poly(ADP-ribose) glycohydrolase isoform b [Homo sapiens];NP_003622.2//poly(ADP-ribose) glycohydrolase isoform a [Homo sapiens];NP_001290418.1//poly(ADP-ribose) glycohydrolase isoform d [Homo sapiens]","4;2//1"]
[83744,4783,0.75,0.52,-0.528378972354789,0.207860723171724,"*",0.11192,"ZNF484","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","NP_001248387.1//zinc finger protein 484 isoform c [Homo sapiens];NP_001341466.1//zinc finger protein 484 isoform d [Homo sapiens]","1//3;3//A2MP1;2//1"]
[10767,6524,6.11,4.24,-0.52710811525553,{"v":2.20896947300679e-06,"d":"2.21E-06"},"*",{"v":3.86784e-07,"d":"3.87E-07"},"HBS1L","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0005622//intracellular","GO:0003746//translation elongation factor activity;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0043928//exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay;GO:0007165//signal transduction;GO:0006412//translation","K14416//elongation factor 1 alpha-like protein","NP_006611.1//HBS1-like protein isoform 1 [Homo sapiens];NP_001138679.1//HBS1-like protein isoform 3 [Homo sapiens];NP_001138630.1//HBS1-like protein isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[5074,7554,7.82,5.43,-0.526216409502991,{"v":8.54777626106001e-08,"d":"8.55E-08"},"*",{"v":1.221646e-08,"d":"1.22E-08"},"PAWR","GO:0005884//actin filament;GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0005737//cytoplasm","GO:0003779//actin binding;GO:0003714//transcription corepressor activity;GO:0043522//leucine zipper domain binding;GO:0019899//enzyme binding","GO:1901300//positive regulation of hydrogen peroxide-mediated programmed cell death;GO:0042986//positive regulation of amyloid precursor protein biosynthetic process;GO:0097190//apoptotic signaling pathway;GO:0006351//transcription, DNA-templated;GO:0010628//positive regulation of gene expression;GO:0048147//negative regulation of fibroblast proliferation;GO:0006915//apoptotic process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0042094//interleukin-2 biosynthetic process;GO:0050860//negative regulation of T cell receptor signaling pathway;GO:2000774//positive regulation of cellular senescence;GO:0043065//positive regulation of apoptotic process;GO:0042130//negative regulation of T cell proliferation;GO:0051017//actin filament bundle assembly;GO:0030889//negative regulation of B cell proliferation","K12581//CCR4-NOT transcription complex subunit 7/8;K13172//serine/arginine repetitive matrix protein 2;K01064//wingless-type MMTV integration site family, member 9","NP_001341662.1//PRKC apoptosis WT1 regulator protein isoform 2 [Homo sapiens];NP_002574.2//PRKC apoptosis WT1 regulator protein isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[10269,3165,24.56,17.06,-0.525692914051889,{"v":3.27742413793103e-12,"d":"3.28E-12"},"*",{"v":2.856e-13,"d":"2.86E-13"},"ZMPSTE24","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005637//nuclear inner membrane","GO:0046872//metal ion binding;GO:0004222//metalloendopeptidase activity;GO:0008235//metalloexopeptidase activity","GO:0006508//proteolysis;GO:0030327//prenylated protein catabolic process;GO:0006998//nuclear envelope organization;GO:0071586//CAAX-box protein processing","K06013//STE24 endopeptidase [EC:3.4.24.84]","NP_005848.2//CAAX prenyl protease 1 homolog [Homo sapiens]",4]
[26508,4131,2.49,1.73,-0.525373704431356,0.0195166093290949,"*",0.00730254,"HEYL","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm","GO:0003714//transcription corepressor activity;GO:0046982//protein heterodimerization activity;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0050683//AF-1 domain binding;GO:0000983//transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding;GO:0042803//protein homodimerization activity;GO:0001106//RNA polymerase II transcription corepressor activity;GO:0035939//microsatellite binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0000988//transcription factor activity, protein binding;GO:0008134//transcription factor binding;GO:0003700//DNA binding transcription factor activity","GO:0060412//ventricular septum morphogenesis;GO:0045666//positive regulation of neuron differentiation;GO:0003198//epithelial to mesenchymal transition involved in endocardial cushion formation;GO:0060317//cardiac epithelial to mesenchymal transition;GO:0014031//mesenchymal cell development;GO:2000824//negative regulation of androgen receptor activity;GO:0003184//pulmonary valve morphogenesis;GO:0060766//negative regulation of androgen receptor signaling pathway;GO:0003203//endocardial cushion morphogenesis;GO:0003181//atrioventricular valve morphogenesis;GO:0072014//proximal tubule development;GO:0032835//glomerulus development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0003151//outflow tract morphogenesis;GO:0003208//cardiac ventricle morphogenesis;GO:0035914//skeletal muscle cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0071773//cellular response to BMP stimulus;GO:0007219//Notch signaling pathway","K09091//hairy and enhancer of split related with YRPW motif","NP_055386.1//hairy/enhancer-of-split related with YRPW motif-like protein [Homo sapiens]","3//A2MP1"]
[10457,2764,1.05,0.73,-0.524420958786106,0.283747183382019,"*",0.164184,"GPNMB","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0042470//melanosome;GO:0005886//plasma membrane","GO:0045545//syndecan binding;GO:0005178//integrin binding;GO:0048018//receptor ligand activity;GO:0008201//heparin binding;GO:0042056//chemoattractant activity","GO:1901215//negative regulation of neuron death;GO:0001649//osteoblast differentiation;GO:0030335//positive regulation of cell migration;GO:0032720//negative regulation of tumor necrosis factor production;GO:0031954//positive regulation of protein autophosphorylation;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle;GO:0042130//negative regulation of T cell proliferation;GO:0034103//regulation of tissue remodeling;GO:0001934//positive regulation of protein phosphorylation;GO:0001818//negative regulation of cytokine production;GO:0008285//negative regulation of cell proliferation;GO:0030282//bone mineralization;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0007155//cell adhesion;GO:0045765//regulation of angiogenesis;GO:0050868//negative regulation of T cell activation;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0050918//positive chemotaxis","K20732//transmembrane glycoprotein NMB","BAG65446.1//unnamed protein product [Homo sapiens];NP_002501.1//transmembrane glycoprotein NMB isoform b precursor [Homo sapiens]","1//3;2//1"]
[84733,4161,12.64,8.79,-0.524061393033699,{"v":5.39041527258383e-07,"d":"5.39E-07"},"*",{"v":8.55434e-08,"d":"8.55E-08"},"CBX2","GO:0035102//PRC1 complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031519//PcG protein complex;GO:0000791//euchromatin;GO:0000792//heterochromatin","GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0035064//methylated histone binding","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0030154//cell differentiation;GO:0016569//covalent chromatin modification;GO:0006351//transcription, DNA-templated;GO:0045137//development of primary sexual characteristics","K11451//chromobox protein 2","NP_005180.1//chromobox protein homolog 2 isoform 1 [Homo sapiens];NP_116036.1//chromobox protein homolog 2 isoform 2 [Homo sapiens]","3//A2MP1;2//1"]
[83903,2797,10.68,7.43,-0.523477531148958,{"v":3.04684425340438E-5,"d":"3.05E-05"},"*",{"v":6.44312e-06,"d":"6.44E-06"},"HASPIN","GO:0005634//nucleus;GO:0005819//spindle;GO:0005813//centrosome;GO:0005694//chromosome;GO:0005737//cytoplasm","GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0072354//histone kinase activity (H3-T3 specific)","GO:2000751//histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore;GO:0071459//protein localization to chromosome, centromeric region;GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction;GO:0007064//mitotic sister chromatid cohesion","K16315//serine/threonine-protein kinase haspin [EC:2.7.11.1]","NP_114171.2//serine/threonine-protein kinase haspin [Homo sapiens]","2//1"]
[11127,6277,5.3,3.69,-0.522371543390165,{"v":9.39153988181818e-06,"d":"9.39E-06"},"*",{"v":1.810814e-06,"d":"1.81E-06"},"KIF3A","NA","NA","NA","K10394//kinesin family member 3A","XP_008989605.1//PREDICTED: kinesin-like protein KIF3A isoform X5 [Callithrix jacchus];XP_002744651.2//PREDICTED: kinesin-like protein KIF3A isoform X1 [Callithrix jacchus];XP_008989602.1//PREDICTED: kinesin-like protein KIF3A isoform X4 [Callithrix jacchus]","6;1//3"]
[83648,4093,4.09,2.85,-0.521138923889645,0.00250494663107801,"*",0.000757882,"FAM167A","NA","NA","NA","NA","XP_017739197.1//PREDICTED: protein FAM167A isoform X2 [Rhinopithecus bieti]","2//1"]
[25966,6349,2.18,1.52,-0.520256811333341,0.00666115498205177,"*",2.20718E-3,"C2CD2","GO:0005634//nucleus;GO:0005829//cytosol;GO:0016021//integral component of membrane","NA","NA","K22069//LYR motif-containing protein 4;K01368//cathepsin S [EC:3.4.22.27];K03129//transcription initiation factor TFIID subunit 4;K17985//activating molecule in BECN1-regulated autophagy protein 1;K02184//formin 2","NP_056315.1//C2 domain-containing protein 2 isoform 1 [Homo sapiens]","1//3;2//1"]
[23509,5160,23.27,16.23,-0.519808210857377,{"v":1.28653132075472E-20,"d":"1.29E-20"},"*",{"v":5.976e-22,"d":"5.98E-22"},"POFUT1","GO:0016020//membrane;GO:0005783//endoplasmic reticulum","GO:0008417//fucosyltransferase activity;GO:0046922//peptide-O-fucosyltransferase activity","GO:0008593//regulation of Notch signaling pathway;GO:0007399//nervous system development;GO:0001525//angiogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0007507//heart development;GO:0016266//O-glycan processing;GO:0006493//protein O-linked glycosylation;GO:0001756//somitogenesis;GO:0009790//embryo development;GO:0006004//fucose metabolic process;GO:0007219//Notch signaling pathway;GO:0036066//protein O-linked fucosylation","K03691//peptide-O-fucosyltransferase [EC:2.4.1.221]","NP_758436.1//GDP-fucose protein O-fucosyltransferase 1 isoform 2 precursor [Homo sapiens];NP_056167.1//GDP-fucose protein O-fucosyltransferase 1 isoform 1 precursor [Homo sapiens]","1//3"]
[138639,4527,1.59,1.11,-0.518467088934249,0.0578395488324873,"*",0.0249658,"PTPDC1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm","GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity","GO:0060271//cilium assembly;GO:0007224//smoothened signaling pathway","K18078//protein tyrosine phosphatase domain-containing protein 1 [EC:3.1.3.-]","NP_001240758.1//protein tyrosine phosphatase domain-containing protein 1 isoform 3 [Homo sapiens];NP_818931.1//protein tyrosine phosphatase domain-containing protein 1 isoform 2 [Homo sapiens];NP_001240759.1//protein tyrosine phosphatase domain-containing protein 1 isoform 4 [Homo sapiens];NP_689635.3//protein tyrosine phosphatase domain-containing protein 1 isoform 1 [Homo sapiens]","4;1//3;2//1"]
[84940,2386,6,4.19,-0.518012256796529,0.00621916623553954,"*",0.00205294,"CORO6","GO:0015629//actin cytoskeleton","GO:0051015//actin filament binding","GO:0030036//actin cytoskeleton organization","K13886//coronin-1B/1C/6","XP_001137500.1//PREDICTED: coronin-6 isoform X1 [Pan troglodytes];NP_001338231.1//coronin-6 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[23705,4332,7.68,5.37,-0.516184222735744,{"v":1.55261280375587e-05,"d":"1.55E-05"},"*",{"v":3.10542e-06,"d":"3.11E-06"},"CADM1","GO:0070062//extracellular exosome;GO:0016323//basolateral plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005913//cell-cell adherens junction;GO:0005911//cell-cell junction;GO:0016021//integral component of membrane;GO:0045202//synapse;GO:0005886//plasma membrane","GO:0050839//cell adhesion molecule binding;GO:0004872//receptor activity;GO:0005102//receptor binding;GO:0030165//PDZ domain binding;GO:0042803//protein homodimerization activity","GO:0030154//cell differentiation;GO:0007283//spermatogenesis;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0042271//susceptibility to natural killer cell mediated cytotoxicity;GO:0051606//detection of stimulus;GO:0006915//apoptotic process;GO:0034332//adherens junction organization;GO:0002376//immune system process;GO:0007275//multicellular organism development;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0050715//positive regulation of cytokine secretion;GO:0008037//cell recognition","K06781//cell adhesion molecule 1","NP_055148.3//cell adhesion molecule 1 isoform D precursor [Homo sapiens];NP_001287973.1//cell adhesion molecule 1 isoform B precursor [Homo sapiens];XP_003952094.1//PREDICTED: cell adhesion molecule 1 isoform X1 [Pan troglodytes];NP_001091987.1//cell adhesion molecule 1 isoform E precursor [Homo sapiens];NP_001287974.1//cell adhesion molecule 1 isoform C precursor [Homo sapiens]","1//3;3//A2MP1"]
[23443,5803,3.23,2.26,-0.515211392278737,0.00153629617522659,"*",0.000445674,"SLC35A3","NA","NA","NA","K15272//solute carrier family 35 (UDP-sugar transporter), member A1/2/3","XP_003784169.2//PREDICTED: UDP-N-acetylglucosamine transporter [Otolemur garnettii];XP_005542670.1//PREDICTED: UDP-N-acetylglucosamine transporter isoform X1 [Macaca fascicularis];XP_017720626.1//PREDICTED: UDP-N-acetylglucosamine transporter [Rhinopithecus bieti]","1//3;2//1"]
[51304,9463,8.16,5.71,-0.515078406608653,{"v":2.4875843991584E-5,"d":"2.49E-05"},"*",{"v":5.18104e-06,"d":"5.18E-06"},"ZDHHC3","GO:0016020//membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0016409//palmitoyltransferase activity;GO:0019706//protein-cysteine S-palmitoyltransferase activity","GO:0006605//protein targeting;GO:0018345//protein palmitoylation","K20029//palmitoyltransferase ZDHHC3/7/25 [EC:2.3.1.225]","XP_007982106.1//PREDICTED: palmitoyltransferase ZDHHC3 isoform X7 [Chlorocebus sabaeus];NP_001336306.1//palmitoyltransferase ZDHHC3 isoform 6 [Homo sapiens];NP_057682.1//palmitoyltransferase ZDHHC3 isoform 2 [Homo sapiens];NP_001336305.1//palmitoyltransferase ZDHHC3 isoform 5 [Homo sapiens];XP_011532099.1//PREDICTED: palmitoyltransferase ZDHHC3 isoform X2 [Homo sapiens];NP_001128651.1//palmitoyltransferase ZDHHC3 isoform 1 [Homo sapiens];NP_001317690.1//palmitoyltransferase ZDHHC3 isoform 4 [Homo sapiens]","1//3;2//1"]
[11213,8168,0.2,0.14,-0.514573172829758,0.463031673174794,"*",0.313258,"IRAK3","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0000287//magnesium ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity","GO:0032494//response to peptidoglycan;GO:0043407//negative regulation of MAP kinase activity;GO:0010933//positive regulation of macrophage tolerance induction;GO:0042177//negative regulation of protein catabolic process;GO:0032715//negative regulation of interleukin-6 production;GO:0032695//negative regulation of interleukin-12 production;GO:0032496//response to lipopolysaccharide;GO:0043330//response to exogenous dsRNA;GO:0032720//negative regulation of tumor necrosis factor production;GO:0070498//interleukin-1-mediated signaling pathway;GO:0034122//negative regulation of toll-like receptor signaling pathway;GO:0010936//negative regulation of macrophage cytokine production;GO:0070555//response to interleukin-1;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0001960//negative regulation of cytokine-mediated signaling pathway;GO:0045824//negative regulation of innate immune response;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0006468//protein phosphorylation;GO:0043242//negative regulation of protein complex disassembly;GO:0046777//protein autophosphorylation;GO:0043244//regulation of protein complex disassembly;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0019221//cytokine-mediated signaling pathway;GO:0009615//response to virus","K04732//interleukin-1 receptor-associated kinase 3 [EC:2.7.11.1]","NP_009130.2//interleukin-1 receptor-associated kinase 3 isoform a [Homo sapiens];NP_001135995.1//interleukin-1 receptor-associated kinase 3 isoform b [Homo sapiens]","1//3;2//1"]
[378708,1243,9.28,6.5,-0.513685087211755,0.0188104048454301,"*",0.00700886,"CENPS","GO:0000776//kinetochore;GO:0043240//Fanconi anaemia nuclear complex;GO:0071821//FANCM-MHF complex","GO:0003682//chromatin binding;GO:0046982//protein heterodimerization activity;GO:0003690//double-stranded DNA binding","GO:0000712//resolution of meiotic recombination intermediates;GO:0006281//DNA repair;GO:0031297//replication fork processing;GO:0051382//kinetochore assembly","K11511//centromere protein S","XP_003274282.1//PREDICTED: centromere protein S [Nomascus leucogenys]","2//1"]
[79647,2719,23.95,16.78,-0.513282940183719,{"v":5.37508575172414e-10,"d":"5.38E-10"},"*",{"v":5.85492e-11,"d":"5.85E-11"},"AKIRIN1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K17776//metaxin;K11447//histone demethylase [EC:1.14.11.-];K01064//wingless-type MMTV integration site family, member 9","NP_078871.1//akirin-1 isoform 1 [Homo sapiens];NP_001129747.1//akirin-1 isoform 2 [Homo sapiens]","1//3;2//1"]
[1954,11167,9.4,6.59,-0.512382291556948,{"v":1.20752920903104E-15,"d":"1.21E-15"},"*",{"v":8.03558e-17,"d":"8.04E-17"},"MEGF8","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0016021//integral component of membrane","GO:0005509//calcium ion binding","GO:0010468//regulation of gene expression;GO:0055113//epiboly involved in gastrulation with mouth forming second;GO:0003143//embryonic heart tube morphogenesis;GO:0071907//determination of digestive tract left/right asymmetry;GO:0097155//fasciculation of sensory neuron axon;GO:0030509//BMP signaling pathway;GO:0035108//limb morphogenesis;GO:0030326//embryonic limb morphogenesis;GO:0061371//determination of heart left/right asymmetry;GO:0048704//embryonic skeletal system morphogenesis;GO:0060971//embryonic heart tube left/right pattern formation;GO:0048842//positive regulation of axon extension involved in axon guidance;GO:0097094//craniofacial suture morphogenesis;GO:0060972//left/right pattern formation;GO:0042074//cell migration involved in gastrulation;GO:0060976//coronary vasculature development","K16628//collagen, type VII, alpha;K22020//mucin-19","BAA32469.2//MEGF8, partial [Homo sapiens];NP_001258867.1//multiple epidermal growth factor-like domains protein 8 isoform 1 precursor [Homo sapiens]","1//3;2//1"]
[23729,3838,9.81,6.88,-0.511844571517141,{"v":4.15885795141977e-06,"d":"4.16E-06"},"*",{"v":7.61008e-07,"d":"7.61E-07"},"SHPK","GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0005524//ATP binding;GO:0016773//phosphotransferase activity, alcohol group as acceptor;GO:0050277//sedoheptulokinase activity","GO:0016310//phosphorylation;GO:0071222//cellular response to lipopolysaccharide;GO:0043030//regulation of macrophage activation;GO:0050727//regulation of inflammatory response;GO:0006098//pentose-phosphate shunt;GO:0009052//pentose-phosphate shunt, non-oxidative branch;GO:0005975//carbohydrate metabolic process;GO:0071353//cellular response to interleukin-4;GO:0035963//cellular response to interleukin-13","K11214//sedoheptulokinase [EC:2.7.1.14]","NP_037408.2//sedoheptulokinase [Homo sapiens]","2//1"]
[56261,5478,4.96,3.48,-0.511252814538147,{"v":9.65455313693399e-05,"d":"9.65E-05"},"*",{"v":2.2157e-05,"d":"2.22E-05"},"GPCPD1","GO:0005829//cytosol;GO:0005737//cytoplasm","GO:2001070//starch binding;GO:0047389//glycerophosphocholine phosphodiesterase activity;GO:0008889//glycerophosphodiester phosphodiesterase activity","GO:0030643//cellular phosphate ion homeostasis;GO:0007519//skeletal muscle tissue development;GO:0046475//glycerophospholipid catabolic process","K18695//glycerophosphocholine phosphodiesterase GPCPD1 [EC:3.1.4.2]","NP_062539.1//glycerophosphocholine phosphodiesterase GPCPD1 [Homo sapiens]","3//A2MP1"]
[388531,2894,0.47,0.33,-0.510194732319184,0.520343732904264,"*",0.36441,"RGS9BP","GO:0016021//integral component of membrane;GO:0001750//photoreceptor outer segment","NA","GO:0050908//detection of light stimulus involved in visual perception;GO:0009968//negative regulation of signal transduction","K03129//transcription initiation factor TFIID subunit 4;K13172//serine/arginine repetitive matrix protein 2;K06568//mucin-1","NP_997274.2//regulator of G-protein signaling 9-binding protein [Homo sapiens]","2//1"]
[8888,6198,11.49,8.07,-0.509738219368333,{"v":9.4511862778127E-11,"d":"9.45E-11"},"*",{"v":9.41332e-12,"d":"9.41E-12"},"MCM3AP","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005643//nuclear pore;GO:0031965//nuclear membrane;GO:0005829//cytosol","GO:0003677//DNA binding;GO:0016746//transferase activity, transferring acyl groups;GO:0003676//nucleic acid binding","GO:0002376//immune system process;GO:0006606//protein import into nucleus;GO:0051028//mRNA transport","K16734//SAC3 domain-containing protein 1;K07945//ADP-ribosylation factor-like protein 4","NP_003897.2//germinal-center associated nuclear protein [Homo sapiens]",4]
[80856,7548,3.7,2.6,-0.509013647487857,{"v":5.59686989807475e-05,"d":"5.60E-05"},"*",{"v":1.23752E-5,"d":"1.24E-05"},"LNPK","GO:0005654//nucleoplasm;GO:0005783//endoplasmic reticulum;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0098826//endoplasmic reticulum tubular network membrane;GO:0005789//endoplasmic reticulum membrane","GO:0046872//metal ion binding;GO:0042802//identical protein binding","GO:1903373//positive regulation of endoplasmic reticulum tubular network organization;GO:0060173//limb development;GO:0007596//blood coagulation;GO:0071788//endoplasmic reticulum tubular network maintenance;GO:0032330//regulation of chondrocyte differentiation;GO:0035115//embryonic forelimb morphogenesis;GO:0042733//embryonic digit morphogenesis","K17776//metaxin;K11447//histone demethylase [EC:1.14.11.-];K01064//wingless-type MMTV integration site family, member 9","NP_001291938.1//protein lunapark isoform 2 [Homo sapiens];NP_001291937.1//protein lunapark isoform 1 precursor [Homo sapiens];CAH56306.1//hypothetical protein, partial [Homo sapiens];NP_001291939.1//protein lunapark isoform 3 precursor [Homo sapiens];NP_085153.1//protein lunapark isoform 4 [Homo sapiens]","1//3;2//1"]
[25833,3013,0.64,0.45,-0.508146903670325,0.413793209257842,"*",0.270854,"POU2F3","GO:0005634//nucleus","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0008544//epidermis development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0043922//negative regulation by host of viral transcription","K09364//POU domain transcription factor, class 2","XP_008019405.1//PREDICTED: POU domain, class 2, transcription factor 3 [Chlorocebus sabaeus];NP_001231611.1//POU domain, class 2, transcription factor 3 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[4076,5328,67.62,47.56,-0.507701301147721,{"v":2.2623142159292e-50,"d":"2.26E-50"},"*",{"v":3.20072e-52,"d":"3.20E-52"},"CAPRIN1","GO:0016020//membrane;GO:0030425//dendrite;GO:0010494//cytoplasmic stress granule;GO:0005887//integral component of plasma membrane;GO:0005829//cytosol;GO:0000932//P-body","GO:0003723//RNA binding","GO:0050775//positive regulation of dendrite morphogenesis;GO:0017148//negative regulation of translation;GO:0061003//positive regulation of dendritic spine morphogenesis","K18743//caprin-1","XP_014970037.1//PREDICTED: caprin-1 isoform X1 [Macaca mulatta]","4;2//1"]
[399473,5075,2.77,1.95,-0.506411852299578,0.00855633652862139,"*",0.00291014,"SPRED3","GO:0016020//membrane","NA","GO:0007275//multicellular organism development;GO:0009966//regulation of signal transduction","K04703//sprouty-related, EVH1 domain-containing protein","XP_021786753.1//LOW QUALITY PROTEIN: sprouty-related, EVH1 domain-containing protein 3 [Papio anubis]","2//1"]
[11254,4579,0.44,0.31,-0.505235308250422,0.363739873808075,"*",0.224474,"SLC6A14","GO:0070062//extracellular exosome;GO:0005887//integral component of plasma membrane;GO:0031526//brush border membrane;GO:0016021//integral component of membrane;GO:0031982//vesicle;GO:0005886//plasma membrane","GO:0005328//neurotransmitter:sodium symporter activity;GO:0005215//transporter activity;GO:0015171//amino acid transmembrane transporter activity","GO:0006810//transport;GO:0006865//amino acid transport;GO:0006520//cellular amino acid metabolic process;GO:0009636//response to toxic substance","K05038//solute carrier family 6 (neurotransmitter transporter, amino acid) member 5/7/9/14","NP_009162.1//sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) [Homo sapiens]",4]
[114907,6763,1.49,1.05,-0.504923002796039,0.0426835689968321,"*",0.01771312,"FBXO32","GO:0005654//nucleoplasm;GO:0030018//Z disc;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0019005//SCF ubiquitin ligase complex","GO:0004842//ubiquitin-protein transferase activity","GO:0043687//post-translational protein modification;GO:0014894//response to denervation involved in regulation of muscle adaptation;GO:0016567//protein ubiquitination;GO:0000209//protein polyubiquitination;GO:0071549//cellular response to dexamethasone stimulus","K10305//F-box protein 25/32","XP_007999672.1//PREDICTED: F-box only protein 32 [Chlorocebus sabaeus];NP_001229392.1//F-box only protein 32 isoform 3 [Homo sapiens];AAI00021.1//FBXO32 protein, partial [Homo sapiens]","1//3;3//A2MP1;2//1"]
[54821,4380,5.5,3.88,-0.503374966224894,0.000278366014196451,"*",{"v":6.97222e-05,"d":"6.97E-05"},"ERCC6L","GO:0016020//membrane;GO:0005829//cytosol;GO:0000777//condensed chromosome kinetochore","GO:0003677//DNA binding;GO:0005524//ATP binding;GO:0004386//helicase activity","GO:0007062//sister chromatid cohesion;GO:0051301//cell division","K20093//DNA excision repair protein ERCC-6-like [EC:3.6.4.12]","NP_060139.2//DNA excision repair protein ERCC-6-like isoform a [Homo sapiens]","3//A2MP1;2//1"]
[345557,7739,0.17,0.12,-0.502500340529183,0.520436776039338,"*",0.36441,"PLCXD3","NA","NA","NA","K13749//solute carrier family 24 (sodium/potassium/calcium exchanger), member 1;K01027//3-oxoacid CoA-transferase [EC:2.8.3.5]","XP_019604115.1//PREDICTED: PI-PLC X domain-containing protein 3 [Rhinolophus sinicus]","2//1"]
[9697,7065,13.43,9.48,-0.502500340529183,{"v":1.03459614232331E-13,"d":"1.03E-13"},"*",{"v":7.97288e-15,"d":"7.97E-15"},"TRAM2","GO:0016021//integral component of membrane","NA","GO:0015031//protein transport;GO:0045048//protein insertion into ER membrane;GO:0032964//collagen biosynthetic process","K14010//translocating chain-associated membrane protein 1","NP_036420.1//translocating chain-associated membrane protein 2 [Homo sapiens]","3//A2MP1"]
[23307,4336,10.45,7.38,-0.501810220907849,{"v":5.32290018957346e-07,"d":"5.32E-07"},"*",{"v":8.4372e-08,"d":"8.44E-08"},"FKBP15","GO:0016020//membrane;GO:0030424//axon;GO:0005884//actin filament;GO:0030426//growth cone;GO:0005769//early endosome","GO:0003779//actin binding","GO:0010923//negative regulation of phosphatase activity;GO:0006897//endocytosis","K17478//FK506-binding protein 15","NP_056073.1//FK506-binding protein 15 [Homo sapiens]","1//3"]
[79923,2055,2.59,1.83,-0.501108449402511,0.125338930942861,"*",0.0608334,"NANOG","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0010468//regulation of gene expression;GO:0001714//endodermal cell fate specification;GO:0030154//cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0035019//somatic stem cell population maintenance;GO:0008283//cell proliferation;GO:0019827//stem cell population maintenance;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045595//regulation of cell differentiation","K10164//homeobox protein Nanog","NP_001284627.1//homeobox protein NANOG isoform 2 [Homo sapiens];NP_079141.2//homeobox protein NANOG isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[84529,2738,5.6,3.96,-0.499926396865357,0.0052292940947226,"*",1.693448E-3,"C15orf41","NA","NA","NA","NA","NP_001308687.1//uncharacterized protein C15orf41 isoform 5 [Homo sapiens];EAW92338.1//chromosome 15 open reading frame 41, isoform CRA_c [Homo sapiens];XP_016783402.1//PREDICTED: uncharacterized protein C15orf41 homolog isoform X4 [Pan troglodytes];XP_016783404.1//PREDICTED: uncharacterized protein C15orf41 homolog isoform X6 [Pan troglodytes];XP_016783401.1//PREDICTED: uncharacterized protein C15orf41 homolog isoform X3 [Pan troglodytes];XP_017395001.1//PREDICTED: uncharacterized protein C15orf41 homolog isoform X2 [Cebus capucinus imitator];NP_001123482.1//uncharacterized protein C15orf41 isoform 1 [Homo sapiens]","1//3;2//1;5"]
[63979,10412,3.59,2.54,-0.499155347050885,{"v":1.84047857371097e-06,"d":"1.84E-06"},"*",{"v":3.17308e-07,"d":"3.17E-07"},"FIGNL1","GO:0000228//nuclear chromosome;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm","GO:0000287//magnesium ion binding;GO:0016787//hydrolase activity;GO:0005524//ATP binding","GO:0046034//ATP metabolic process;GO:0001649//osteoblast differentiation;GO:0033687//osteoblast proliferation;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0010569//regulation of double-strand break repair via homologous recombination;GO:0007140//male meiotic nuclear division;GO:0071479//cellular response to ionizing radiation;GO:0051726//regulation of cell cycle","K13254//spastin [EC:3.6.4.3]","NP_071399.2//fidgetin-like protein 1 isoform 1 [Homo sapiens]","1//3;3//A2MP1;2//1;5"]
[22909,4659,6.44,4.56,-0.498026863949875,{"v":3.12275928440908e-05,"d":"3.12E-05"},"*",{"v":6.63298e-06,"d":"6.63E-06"},"FAN1","GO:0045171//intercellular bridge;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol","GO:0000287//magnesium ion binding;GO:0008409//5'-3' exonuclease activity;GO:0070336//flap-structured DNA binding;GO:0140036//ubiquitin-dependent protein binding;GO:0004528//phosphodiesterase I activity;GO:0017108//5'-flap endonuclease activity","GO:0006281//DNA repair;GO:0036297//interstrand cross-link repair;GO:0000724//double-strand break repair via homologous recombination;GO:0033683//nucleotide-excision repair, DNA incision;GO:0006289//nucleotide-excision repair","K15363//fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]","NP_001139566.1//fanconi-associated nuclease 1 isoform b [Homo sapiens];NP_055782.3//fanconi-associated nuclease 1 isoform a [Homo sapiens]","1//3;4"]
[91754,6252,9.02,6.39,-0.497311502308387,{"v":9.01078096421471e-09,"d":"9.01E-09"},"*",{"v":1.13495e-09,"d":"1.13E-09"},"NEK9","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005813//centrosome","GO:0046872//metal ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0019901//protein kinase binding","GO:0007077//mitotic nuclear envelope disassembly;GO:0051301//cell division","K20878//NIMA (never in mitosis gene a)-related kinase 9 [EC:2.7.11.1]","NP_149107.4//serine/threonine-protein kinase Nek9 isoform 2 [Homo sapiens];NP_001316166.1//serine/threonine-protein kinase Nek9 isoform 1 [Homo sapiens]","1//3;5"]
[7565,2746,1.89,1.34,-0.4961532337633,0.142014888677831,"*",0.0711408,"ZNF17","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","NP_008890.2//zinc finger protein 17 isoform 2 [Homo sapiens];NP_001317546.1//zinc finger protein 17 isoform 1 [Homo sapiens]","1//3;2//1"]
[9927,4653,24.17,17.14,-0.495850363653083,{"v":8.37432770313987e-16,"d":"8.37E-16"},"*",{"v":5.50984e-17,"d":"5.51E-17"},"MFN2","GO:0015630//microtubule cytoskeleton;GO:0016021//integral component of membrane;GO:0005741//mitochondrial outer membrane;GO:0031306//intrinsic component of mitochondrial outer membrane","GO:0031625//ubiquitin protein ligase binding;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0061734//parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0046580//negative regulation of Ras protein signal transduction;GO:0051646//mitochondrion localization;GO:0007006//mitochondrial membrane organization;GO:0048593//camera-type eye morphogenesis;GO:0006626//protein targeting to mitochondrion;GO:0008053//mitochondrial fusion;GO:0034497//protein localization to phagophore assembly site;GO:0001825//blastocyst formation","K06030//mitofusin 2 [EC:3.6.5.-]","XP_011725122.1//PREDICTED: mitofusin-2 [Macaca nemestrina]","1//3;3//A2MP1"]
[92017,8183,1.24,0.88,-0.494764691749578,0.0277966540490306,"*",0.01086008,"SNX29","GO:0070062//extracellular exosome","GO:0035091//phosphatidylinositol binding","NA","K17935//sorting nexin-29","EAW85124.1//hCG2042874, isoform CRA_a, partial [Homo sapiens]",4]
[3622,2465,3.79,2.69,-0.494591675614468,0.0409069111724556,"*",0.01688364,"ING2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016602//CCAAT-binding factor complex;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016580//Sin3 complex;GO:0005886//plasma membrane","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0035064//methylated histone binding;GO:0032403//protein complex binding;GO:0035091//phosphatidylinositol binding","GO:0007141//male meiosis I;GO:0006355//regulation of transcription, DNA-templated;GO:0040008//regulation of growth;GO:2001020//regulation of response to DNA damage stimulus;GO:0007283//spermatogenesis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0031065//positive regulation of histone deacetylation;GO:2001234//negative regulation of apoptotic signaling pathway;GO:0008285//negative regulation of cell proliferation;GO:0030317//flagellated sperm motility;GO:0007165//signal transduction;GO:0006351//transcription, DNA-templated;GO:0007286//spermatid development;GO:0048133//male germ-line stem cell asymmetric division;GO:1902166//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0016569//covalent chromatin modification;GO:0072520//seminiferous tubule development;GO:2000772//regulation of cellular senescence;GO:0042981//regulation of apoptotic process;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway","K19198//inhibitor of growth protein 2","NP_001555.1//inhibitor of growth protein 2 isoform 1 [Homo sapiens];NP_001278888.1//inhibitor of growth protein 2 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[54892,4114,18.62,13.22,-0.494130896051102,{"v":2.474628184E-11,"d":"2.47E-11"},"*",{"v":2.32374E-12,"d":"2.32E-12"},"NCAPG2","GO:0016020//membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000796//condensin complex;GO:0016607//nuclear speck","GO:0035064//methylated histone binding","GO:0030261//chromosome condensation;GO:0001833//inner cell mass cell proliferation;GO:0051301//cell division;GO:0007049//cell cycle","K11492//condensin-2 complex subunit G2","NP_001268862.1//condensin-2 complex subunit G2 isoform b [Homo sapiens];NP_060230.5//condensin-2 complex subunit G2 isoform a [Homo sapiens]","6;1//3"]
[255738,3731,3.32,2.36,-0.492396381985084,0.0168115041214603,"*",0.00616934,"PCSK9","GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005770//late endosome;GO:1990667//PCSK9-AnxA2 complex;GO:0005764//lysosome;GO:0048471//perinuclear region of cytoplasm;GO:0030134//COPII-coated ER to Golgi transport vesicle;GO:0009986//cell surface;GO:1990666//PCSK9-LDLR complex;GO:0005886//plasma membrane;GO:0005769//early endosome","GO:0004252//serine-type endopeptidase activity;GO:0003723//RNA binding;GO:0030169//low-density lipoprotein particle binding;GO:0034185//apolipoprotein binding;GO:0070326//very-low-density lipoprotein particle receptor binding;GO:0043621//protein self-association;GO:0034190//apolipoprotein receptor binding;GO:0019871//sodium channel inhibitor activity;GO:0030547//receptor inhibitor activity;GO:0050750//low-density lipoprotein particle receptor binding;GO:0034189//very-low-density lipoprotein particle binding","GO:0007041//lysosomal transport;GO:0001822//kidney development;GO:0008203//cholesterol metabolic process;GO:0009267//cellular response to starvation;GO:0002092//positive regulation of receptor internalization;GO:1905598//negative regulation of low-density lipoprotein receptor activity;GO:0042632//cholesterol homeostasis;GO:2000650//negative regulation of sodium ion transmembrane transporter activity;GO:0042157//lipoprotein metabolic process;GO:0032802//low-density lipoprotein particle receptor catabolic process;GO:1905601//negative regulation of receptor-mediated endocytosis involved in cholesterol transport;GO:0016540//protein autoprocessing;GO:0043525//positive regulation of neuron apoptotic process;GO:0010989//negative regulation of low-density lipoprotein particle clearance;GO:0030182//neuron differentiation;GO:0001889//liver development;GO:0006641//triglyceride metabolic process;GO:0001920//negative regulation of receptor recycling;GO:0032805//positive regulation of low-density lipoprotein particle receptor catabolic process;GO:0032869//cellular response to insulin stimulus;GO:0006644//phospholipid metabolic process;GO:1905596//negative regulation of low-density lipoprotein particle receptor binding","K13050//proprotein convertase subtilisin/kexin type 9 [EC:3.4.21.-]","XP_003815030.1//PREDICTED: proprotein convertase subtilisin/kexin type 9 isoform X2 [Pan paniscus]","3//A2MP1"]
[57379,2815,0.9,0.64,-0.491853096329675,0.36172376119403,"*",0.223026,"AICDA","GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0000178//exosome (RNase complex)","GO:0016814//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines;GO:0042802//identical protein binding;GO:0004126//cytidine deaminase activity;GO:0008270//zinc ion binding;GO:0031625//ubiquitin protein ligase binding","GO:0006397//mRNA processing;GO:0045190//isotype switching;GO:0016446//somatic hypermutation of immunoglobulin genes;GO:0080111//DNA demethylation;GO:0071222//cellular response to lipopolysaccharide;GO:0042742//defense response to bacterium;GO:0016445//somatic diversification of immunoglobulins;GO:0090310//negative regulation of methylation-dependent chromatin silencing;GO:0097752//regulation of DNA stability;GO:0030183//B cell differentiation","K10989//activation-induced cytidine deaminase [EC:3.5.4.38]","NP_001317272.1//single-stranded DNA cytosine deaminase isoform 2 [Homo sapiens];NP_065712.1//single-stranded DNA cytosine deaminase isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[7410,4750,9.67,6.88,-0.491107324774743,{"v":6.86136175609756e-07,"d":"6.86E-07"},"*",{"v":1.109484E-7,"d":"1.11E-07"},"VAV2","GO:0005829//cytosol;GO:0005622//intracellular;GO:0005737//cytoplasm;GO:0005886//plasma membrane","GO:0046872//metal ion binding;GO:0001784//phosphotyrosine residue binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005154//epidermal growth factor receptor binding;GO:0005089//Rho guanyl-nucleotide exchange factor activity","GO:0030032//lamellipodium assembly;GO:0010468//regulation of gene expression;GO:0016477//cell migration;GO:0035556//intracellular signal transduction;GO:0030168//platelet activation;GO:0030193//regulation of blood coagulation;GO:0043065//positive regulation of apoptotic process;GO:0007264//small GTPase mediated signal transduction;GO:0001525//angiogenesis;GO:0007165//signal transduction;GO:0008361//regulation of cell size;GO:0048013//ephrin receptor signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0043087//regulation of GTPase activity;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0035023//regulation of Rho protein signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction","K05730//guanine nucleotide exchange factor VAV","NP_003362.2//guanine nucleotide exchange factor VAV2 isoform 2 [Homo sapiens];NP_001127870.1//guanine nucleotide exchange factor VAV2 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[160335,4346,0.66,0.47,-0.489805267680816,0.161566933852898,"*",0.0830592,"TMTC2","GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","NA","GO:0055074//calcium ion homeostasis","K09667//protein O-GlcNAc transferase [EC:2.4.1.255]","NP_001307251.1//transmembrane and TPR repeat-containing protein 2 isoform 3 precursor [Homo sapiens];XP_012604984.1//transmembrane and TPR repeat-containing protein 2 isoform X3 [Microcebus murinus];NP_689801.1//transmembrane and TPR repeat-containing protein 2 isoform 1 precursor [Homo sapiens]","1//3;2//1"]
[51569,2687,14.57,10.38,-0.489194433706632,{"v":8.00183075246224e-06,"d":"8.00E-06"},"*",{"v":1.525828E-6,"d":"1.53E-06"},"UFM1","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005737//cytoplasm","NA","GO:1990592//protein K69-linked ufmylation;GO:0034976//response to endoplasmic reticulum stress;GO:0033146//regulation of intracellular estrogen receptor signaling pathway;GO:0071569//protein ufmylation;GO:0043066//negative regulation of apoptotic process","K12162//ubiquitin-fold modifier 1","NP_001273633.1//ubiquitin-fold modifier 1 isoform 3 [Homo sapiens];AAK55530.1//PRO3033 [Homo sapiens]","1//3;3//A2MP1"]
[23595,2586,13.65,9.73,-0.488389241026103,{"v":2.92837361783061e-05,"d":"2.93E-05"},"*",{"v":6.16876e-06,"d":"6.17E-06"},"ORC3","GO:0031261//DNA replication preinitiation complex;GO:0000808//origin recognition complex;GO:0005654//nucleoplasm;GO:0000784//nuclear chromosome, telomeric region;GO:0005656//nuclear pre-replicative complex;GO:0005664//nuclear origin of replication recognition complex;GO:0016604//nuclear body","GO:0003688//DNA replication origin binding","GO:0006267//pre-replicative complex assembly involved in nuclear cell cycle DNA replication;GO:0061351//neural precursor cell proliferation;GO:0006260//DNA replication;GO:0000082//G1/S transition of mitotic cell cycle;GO:0006270//DNA replication initiation","K02605//origin recognition complex subunit 3","NP_862820.1//origin recognition complex subunit 3 isoform 1 [Homo sapiens];XP_016866125.1//PREDICTED: origin recognition complex subunit 3 isoform X8 [Homo sapiens];NP_036513.2//origin recognition complex subunit 3 isoform 2 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[79794,5254,11.87,8.47,-0.486886060309708,{"v":5.481581e-09,"d":"5.48E-09"},"*",{"v":6.71214e-10,"d":"6.71E-10"},"C12orf49","GO:0005576//extracellular region","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K04487//cysteine desulfurase [EC:2.8.1.7]","BAC04924.1//unnamed protein product [Homo sapiens];NP_079014.1//UPF0454 protein C12orf49 isoform 1 precursor [Homo sapiens];NP_001340552.1//UPF0454 protein C12orf49 isoform 2 [Homo sapiens];NP_001340553.1//UPF0454 protein C12orf49 isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[10447,2538,12.43,8.87,-0.486820286751421,{"v":8.95637809915092e-05,"d":"8.96E-05"},"*",{"v":2.04706E-5,"d":"2.05E-05"},"FAM3C","GO:0070062//extracellular exosome;GO:0031089//platelet dense granule lumen;GO:0005576//extracellular region","GO:0005125//cytokine activity","GO:0002576//platelet degranulation;GO:0007275//multicellular organism development","K07747//beta-site APP-cleaving enzyme 2 (memapsin 1) [EC:3.4.23.45];K09666//beta-1,2-N-acetylglucosaminyltransferase [EC:2.4.1.-]","NP_055703.1//protein FAM3C precursor [Homo sapiens]","1//3;2//1"]
[100288142,18450,0.42,0.3,-0.485426827170242,0.0838598660416379,"*",0.0380766,"NBPF20","NA","NA","NA","K22244//regenerating islet-derived protein 4","NP_001265196.1//neuroblastoma breakpoint family member 20 [Homo sapiens]","1//3"]
[56853,4181,0.07,0.05,-0.485426827170242,0.782262985507246,"*",0.689316,"CELF4","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0000900//translation repressor activity, nucleic acid binding;GO:0036002//pre-mRNA binding;GO:0003729//mRNA binding;GO:0042835//BRE binding","GO:0006397//mRNA processing;GO:0006376//mRNA splice site selection;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0048026//positive regulation of mRNA splicing, via spliceosome;GO:0007281//germ cell development;GO:0090394//negative regulation of excitatory postsynaptic potential;GO:1902866//regulation of retina development in camera-type eye;GO:0009790//embryo development;GO:0008380//RNA splicing;GO:0048025//negative regulation of mRNA splicing, via spliceosome","K13207//CUG-BP- and ETR3-like factor;K12822//RNA-binding protein 25","XP_010817008.1//PREDICTED: CUGBP Elav-like family member 4 isoform X21 [Bos taurus];XP_022351209.1//CUGBP Elav-like family member 4 isoform X8 [Enhydra lutris kenyoni];XP_022351210.1//CUGBP Elav-like family member 4 isoform X9 [Enhydra lutris kenyoni];XP_020331806.1//octapeptide-repeat protein T2-like, partial [Oncorhynchus kisutch];NP_001340671.1//CUGBP Elav-like family member 4 isoform 18 [Homo sapiens];NP_001340636.1//CUGBP Elav-like family member 4 isoform 21 [Homo sapiens];NP_001340677.1//CUGBP Elav-like family member 4 isoform 33 [Homo sapiens];NP_001340646.1//CUGBP Elav-like family member 4 isoform 20 [Homo sapiens];XP_022351212.1//CUGBP Elav-like family member 4 isoform X11 [Enhydra lutris kenyoni];XP_022351205.1//CUGBP Elav-like family member 4 isoform X5 [Enhydra lutris kenyoni];BAD93011.1//bruno-like 4, RNA binding protein variant, partial [Homo sapiens];NP_001340626.1//CUGBP Elav-like family member 4 isoform 55 [Homo sapiens];XP_022351204.1//CUGBP Elav-like family member 4 isoform X4 [Enhydra lutris kenyoni];XP_022351206.1//CUGBP Elav-like family member 4 isoform X6 [Enhydra lutris kenyoni];XP_022351213.1//CUGBP Elav-like family member 4 isoform X12 [Enhydra lutris kenyoni];XP_022351202.1//CUGBP Elav-like family member 4 isoform X2 [Enhydra lutris kenyoni];XP_022351211.1//CUGBP Elav-like family member 4 isoform X10 [Enhydra lutris kenyoni];XP_022351208.1//CUGBP Elav-like family member 4 isoform X7 [Enhydra lutris kenyoni];XP_022351215.1//CUGBP Elav-like family member 4 isoform X14 [Enhydra lutris kenyoni];XP_021092374.1//CUGBP Elav-like family member 4 isoform X15 [Heterocephalus glaber];XP_022351203.1//CUGBP Elav-like family member 4 isoform X3 [Enhydra lutris kenyoni];XP_010817007.1//PREDICTED: CUGBP Elav-like family member 4 isoform X20 [Bos taurus];XP_022351221.1//CUGBP Elav-like family member 4 isoform X19 [Enhydra lutris kenyoni];XP_013365777.1//PREDICTED: CUGBP Elav-like family member 4 isoform X3 [Chinchilla lanigera]","1//3;3//A2MP1"]
[64844,3489,17.38,12.42,-0.484762908593919,{"v":3.01991964575646E-9,"d":"3.02E-09"},"*",{"v":3.58632E-10,"d":"3.59E-10"},"2019-03-07","NA","GO:0008270//zinc ion binding;GO:0016740//transferase activity","GO:0042130//negative regulation of T cell proliferation;GO:0016567//protein ubiquitination;GO:0002643//regulation of tolerance induction","K10662//E3 ubiquitin-protein ligase MARCH7 [EC:2.3.2.27]","NP_001269736.1//E3 ubiquitin-protein ligase MARCH7 isoform c [Homo sapiens];NP_073737.1//E3 ubiquitin-protein ligase MARCH7 isoform a [Homo sapiens];XP_008997084.1//PREDICTED: E3 ubiquitin-protein ligase MARCH7 isoform X4 [Callithrix jacchus]","1//3;3//A2MP1"]
[338376,1501,1.51,1.08,-0.48351723716161,0.39590808839779,"*",0.255702,"IFNE","GO:0005615//extracellular space","GO:0005132//type I interferon receptor binding;GO:0005125//cytokine activity;GO:0005126//cytokine receptor binding","GO:0051607//defense response to virus;GO:0043330//response to exogenous dsRNA;GO:0042742//defense response to bacterium;GO:0002250//adaptive immune response;GO:0042100//B cell proliferation;GO:0006959//humoral immune response;GO:0002286//T cell activation involved in immune response;GO:0002323//natural killer cell activation involved in immune response;GO:0033141//positive regulation of peptidyl-serine phosphorylation of STAT protein;GO:0030183//B cell differentiation;GO:0019221//cytokine-mediated signaling pathway;GO:0045087//innate immune response","K05442//interferon epsilon","NP_795372.1//interferon epsilon precursor [Homo sapiens]",4]
[6695,4841,6.85,4.9,-0.483322238845318,{"v":4.5505972583883e-05,"d":"4.55E-05"},"*",{"v":9.9336e-06,"d":"9.93E-06"},"SPOCK1","GO:0005615//extracellular space;GO:0016528//sarcoplasm;GO:0031594//neuromuscular junction;GO:0033268//node of Ranvier;GO:0014069//postsynaptic density;GO:0005737//cytoplasm;GO:0005578//proteinaceous extracellular matrix","GO:0004867//serine-type endopeptidase inhibitor activity;GO:0008191//metalloendopeptidase inhibitor activity;GO:0005509//calcium ion binding;GO:0004869//cysteine-type endopeptidase inhibitor activity","GO:0001558//regulation of cell growth;GO:0007399//nervous system development;GO:0007165//signal transduction;GO:0010951//negative regulation of endopeptidase activity;GO:0007155//cell adhesion;GO:0022008//neurogenesis;GO:0010977//negative regulation of neuron projection development;GO:0001764//neuron migration;GO:0010812//negative regulation of cell-substrate adhesion;GO:0021953//central nervous system neuron differentiation","K08136//sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican)","BAD92938.1//sparc/osteonectin, cwcv and kazal-like domains proteoglycan precursor variant, partial [Homo sapiens]","3//A2MP1"]
[2936,3189,137.41,98.35,-0.482490042357883,{"v":5.88496225157233e-64,"d":"5.88E-64"},"*",{"v":5.8577e-66,"d":"5.86E-66"},"GSR","GO:0005759//mitochondrial matrix;GO:0070062//extracellular exosome;GO:0009897//external side of plasma membrane;GO:0005829//cytosol;GO:0005739//mitochondrion","GO:0050661//NADP binding;GO:0009055//electron transfer activity;GO:0050660//flavin adenine dinucleotide binding;GO:0004362//glutathione-disulfide reductase activity","GO:0006749//glutathione metabolic process;GO:0034599//cellular response to oxidative stress;GO:0015949//nucleobase-containing small molecule interconversion;GO:0045454//cell redox homeostasis","K00383//glutathione reductase (NADPH) [EC:1.8.1.7]","NP_000628.2//glutathione reductase, mitochondrial isoform 1 precursor [Homo sapiens];NP_001182031.1//glutathione reductase, mitochondrial isoform 2 [Homo sapiens];NP_001182033.1//glutathione reductase, mitochondrial isoform 4 [Homo sapiens];NP_001182032.1//glutathione reductase, mitochondrial isoform 3 [Homo sapiens]","4;2//1"]
[57472,6347,5.43,3.89,-0.48118204281817,{"v":3.08510085553914e-05,"d":"3.09E-05"},"*",{"v":6.53754e-06,"d":"6.54E-06"},"CNOT6","GO:0016020//membrane;GO:0005634//nucleus;GO:0030014//CCR4-NOT complex;GO:0005829//cytosol","GO:0004535//poly(A)-specific ribonuclease activity;GO:0003723//RNA binding;GO:0046872//metal ion binding;GO:0004532//exoribonuclease activity","GO:2000327//positive regulation of ligand-dependent nuclear receptor transcription coactivator activity;GO:0070966//nuclear-transcribed mRNA catabolic process, no-go decay;GO:0043928//exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0010606//positive regulation of cytoplasmic mRNA processing body assembly;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0035195//gene silencing by miRNA;GO:0008284//positive regulation of cell proliferation","K12603//CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]","NP_001290170.1//CCR4-NOT transcription complex subunit 6 [Homo sapiens]","1//3"]
[57594,3741,5.89,4.22,-0.481024635123276,0.00109668022395023,"*",3.09012E-4,"HOMEZ","GO:0005730//nucleolus;GO:0005829//cytosol","GO:0003677//DNA binding","GO:0006355//regulation of transcription, DNA-templated","K15187//YEATS domain-containing protein 1/3;K19721//collagen, type V/XI/XXIV/XXVII, alpha","XP_020765451.1//homeobox and leucine zipper protein Homez isoform X2 [Odocoileus virginianus texanus]","2//1"]
[10247,1011,12.94,9.28,-0.479640906864935,0.0182377778587085,"*",0.00677152,"RIDA","GO:0005759//mitochondrial matrix;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005777//peroxisome;GO:0005737//cytoplasm","GO:1904013//xenon atom binding;GO:0003723//RNA binding;GO:0036041//long-chain fatty acid binding;GO:0019239//deaminase activity;GO:0046914//transition metal ion binding;GO:1904012//platinum binding;GO:0042803//protein homodimerization activity;GO:0016892//endoribonuclease activity, producing 3'-phosphomonoesters","GO:0030324//lung development;GO:0033993//response to lipid;GO:0001822//kidney development;GO:1901565//organonitrogen compound catabolic process;GO:0070314//G1 to G0 transition;GO:0007420//brain development;GO:0017148//negative regulation of translation;GO:1902074//response to salt;GO:0050680//negative regulation of epithelial cell proliferation","K09022//2-iminobutanoate/2-iminopropanoate deaminase [EC:3.5.99.10]","NP_005827.1//2-iminobutanoate/2-iminopropanoate deaminase [Homo sapiens]","2//1"]
[286207,1722,1.31,0.94,-0.478834149859813,0.395946466459868,"*",0.255702,"CFAP157","GO:0043231//intracellular membrane-bounded organelle;GO:0036064//ciliary basal body;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0008017//microtubule binding","GO:0007288//sperm axoneme assembly","K16628//collagen, type VII, alpha","EAW87684.1//chromosome 9 open reading frame 117, isoform CRA_b [Homo sapiens]","2//1"]
[222236,5271,2.87,2.06,-0.478406399492469,0.014419193631149,"*",0.00519304,"NAPEPLD","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0042622//photoreceptor outer segment membrane","GO:0042802//identical protein binding;GO:0008270//zinc ion binding;GO:0070290//N-acylphosphatidylethanolamine-specific phospholipase D activity;GO:0102200//N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity","GO:0035900//response to isolation stress;GO:0009395//phospholipid catabolic process;GO:0001523//retinoid metabolic process;GO:1903999//negative regulation of eating behavior;GO:0070291//N-acylethanolamine metabolic process;GO:0007568//aging","K13985//N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D [EC:3.1.4.54]","BAG65422.1//unnamed protein product [Homo sapiens]","4;1//3"]
[22908,3670,6.21,4.46,-0.477549558300177,0.00100928420370784,"*",0.00028287,"SACM1L","GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0032281//AMPA glutamate receptor complex;GO:0000139//Golgi membrane","GO:0043812//phosphatidylinositol-4-phosphate phosphatase activity;GO:0034596//phosphatidylinositol phosphate 4-phosphatase activity;GO:0042578//phosphoric ester hydrolase activity;GO:0004438//phosphatidylinositol-3-phosphatase activity;GO:0016791//phosphatase activity;GO:0034593//phosphatidylinositol bisphosphate phosphatase activity","GO:0006661//phosphatidylinositol biosynthetic process;GO:0046856//phosphatidylinositol dephosphorylation","K21797//phosphatidylinositol 4-phosphatase [EC:3.1.3.-]","NP_001306001.1//phosphatidylinositide phosphatase SAC1 isoform 2 [Homo sapiens];NP_054735.3//phosphatidylinositide phosphatase SAC1 isoform 1 [Homo sapiens]","1//3;4"]
[10786,1574,1.28,0.92,-0.476438043942987,0.44073377677734,"*",0.294172,"SLC17A3","GO:0005887//integral component of plasma membrane;GO:0016324//apical plasma membrane;GO:0031526//brush border membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm","GO:0015143//urate transmembrane transporter activity;GO:0019534//toxin transmembrane transporter activity;GO:0008308//voltage-gated anion channel activity;GO:0015562//efflux transmembrane transporter activity;GO:0008514//organic anion transmembrane transporter activity;GO:0015238//drug transmembrane transporter activity;GO:0005436//sodium:phosphate symporter activity","GO:0055085//transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0015711//organic anion transport;GO:0015747//urate transport;GO:0034220//ion transmembrane transport;GO:0015893//drug transport;GO:0006817//phosphate ion transport;GO:0015760//glucose-6-phosphate transport;GO:0006814//sodium ion transport;GO:0046415//urate metabolic process","K12300//MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 1/2/3/4","NP_001091956.1//sodium-dependent phosphate transport protein 4 isoform a [Homo sapiens];NP_006623.2//sodium-dependent phosphate transport protein 4 isoform b [Homo sapiens]","1//3;3//A2MP1"]
[10959,2127,140.99,101.38,-0.475819771158318,{"v":3.20457861276596e-37,"d":"3.20E-37"},"*",{"v":6.60014e-39,"d":"6.60E-39"},"TMED2","GO:0043231//intracellular membrane-bounded organelle;GO:0005783//endoplasmic reticulum;GO:0032580//Golgi cisterna membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0030137//COPI-coated vesicle;GO:0000139//Golgi membrane;GO:0042589//zymogen granule membrane;GO:0030133//transport vesicle;GO:0030663//COPI-coated vesicle membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0012507//ER to Golgi transport vesicle membrane","NA","GO:0032525//somite rostral/caudal axis specification;GO:0048208//COPII vesicle coating;GO:0035459//cargo loading into vesicle;GO:0036342//post-anal tail morphogenesis;GO:0001892//embryonic placenta development;GO:0006903//vesicle targeting;GO:0001756//somitogenesis;GO:0048205//COPI coating of Golgi vesicle;GO:0001893//maternal placenta development;GO:0006810//transport;GO:0060716//labyrinthine layer blood vessel development;GO:0072659//protein localization to plasma membrane;GO:0001701//in utero embryonic development;GO:0007030//Golgi organization;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0010628//positive regulation of gene expression;GO:0035264//multicellular organism growth;GO:0006886//intracellular protein transport;GO:0001947//heart looping;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0034260//negative regulation of GTPase activity;GO:0001843//neural tube closure;GO:0048598//embryonic morphogenesis","K20347//p24 family protein beta-1","XP_012637627.1//transmembrane emp24 domain-containing protein 2 isoform X2 [Microcebus murinus];XP_012637626.1//transmembrane emp24 domain-containing protein 2 isoform X1 [Microcebus murinus]","1//3;3//A2MP1"]
[199745,1611,8.09,5.82,-0.475120549521694,0.0170554884862932,"*",0.00627062,"THAP8","NA","GO:0046872//metal ion binding;GO:0003677//DNA binding","NA","K04632//guanine nucleotide-binding protein G(s) subunit alpha;K09228//KRAB domain-containing zinc finger protein;K22020//mucin-19;K04678//E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26];K04460//serine/threonine-protein phosphatase 5 [EC:3.1.3.16]","NP_001318031.1//THAP domain-containing protein 8 isoform b [Homo sapiens];NP_689871.1//THAP domain-containing protein 8 isoform a [Homo sapiens]","1//3;2//1"]
[23341,5946,3.21,2.31,-0.474680445706245,3.42388131782635E-3,"*",0.001068918,"DNAJC16","GO:0005623//cell;GO:0005829//cytosol;GO:0016021//integral component of membrane","NA","GO:0045454//cell redox homeostasis","K09536//DnaJ homolog subfamily C member 16","NP_056106.1//dnaJ homolog subfamily C member 16 isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[9364,1741,8.03,5.78,-0.474330495016635,0.0102747811764706,"*",3.56472E-3,"RAB28","NA","NA","NA","K07915//Ras-related protein Rab-28","XP_005554549.2//PREDICTED: ras-related protein Rab-28 isoform X2 [Macaca fascicularis];XP_014993487.1//PREDICTED: ras-related protein Rab-28 isoform X1 [Macaca mulatta]","1//3;3//A2MP1;2//1"]
[200942,1999,5.18,3.73,-0.473776467431316,0.0398018671193666,"*",0.01636526,"KLHDC8B","GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0031463//Cul3-RING ubiquitin ligase complex;GO:0030496//midbody","NA","GO:0051301//cell division;GO:0016567//protein ubiquitination;GO:0007049//cell cycle","K15046//influenza virus NS1A-binding protein;K10446//kelch-like protein 8","NP_775817.1//kelch domain-containing protein 8B [Homo sapiens]","2//1"]
[57187,5625,9.26,6.67,-0.473325432075651,{"v":3.44034838636364e-07,"d":"3.44E-07"},"*",{"v":5.30676e-08,"d":"5.31E-08"},"THOC2","GO:0000784//nuclear chromosome, telomeric region;GO:0005654//nucleoplasm;GO:0000347//THO complex;GO:0000445//THO complex part of transcription export complex;GO:0016607//nuclear speck;GO:0000346//transcription export complex","GO:0003729//mRNA binding","GO:0006406//mRNA export from nucleus;GO:0000902//cell morphogenesis;GO:0046784//viral mRNA export from host cell nucleus;GO:0006369//termination of RNA polymerase II transcription;GO:0031124//mRNA 3'-end processing;GO:0048699//generation of neurons;GO:0006405//RNA export from nucleus;GO:0048666//neuron development;GO:0010793//regulation of mRNA export from nucleus;GO:0016973//poly(A)+ mRNA export from nucleus;GO:0001824//blastocyst development;GO:0010977//negative regulation of neuron projection development;GO:0017145//stem cell division;GO:0008380//RNA splicing","K12879//THO complex subunit 2","NP_001075019.1//THO complex subunit 2 [Homo sapiens]","1//3"]
[79739,7837,0.68,0.49,-0.472752997135131,0.154776230308975,"*",0.0790256,"TTLL7","GO:0030425//dendrite;GO:0005929//cilium;GO:0005874//microtubule;GO:0005829//cytosol;GO:0043204//perikaryon","GO:0070740//tubulin-glutamic acid ligase activity;GO:0048487//beta-tubulin binding;GO:0005524//ATP binding;GO:0043014//alpha-tubulin binding","GO:0007399//nervous system development;GO:0018095//protein polyglutamylation;GO:0030154//cell differentiation","K16583//tubulin polyglutamylase TTLL7 [EC:6.-.-.-]","NP_078962.4//tubulin polyglutamylase TTLL7 isoform 1 [Homo sapiens]","1//3;5"]
[421,4056,0.43,0.31,-0.472068444315223,0.49334168956743,"*",0.339848,"ARVCF","GO:0005634//nucleus;GO:0005622//intracellular;GO:0005886//plasma membrane;GO:0005737//cytoplasm","NA","GO:0007155//cell adhesion;GO:0007275//multicellular organism development;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules","K05690//catenin (cadherin-associated protein), delta 1","NP_001661.1//armadillo repeat protein deleted in velo-cardio-facial syndrome [Homo sapiens]","2//1"]
[26286,2809,5.31,3.83,-0.471367468879196,0.010267237329002,"*",0.00356146,"ARFGAP3","GO:0016020//membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0000139//Golgi membrane","GO:0046872//metal ion binding;GO:0008565//protein transporter activity;GO:0005096//GTPase activator activity","GO:0006886//intracellular protein transport;GO:0009306//protein secretion;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0016192//vesicle-mediated transport","K12493//ADP-ribosylation factor GTPase-activating protein 2/3","NP_001135765.1//ADP-ribosylation factor GTPase-activating protein 3 isoform 2 [Homo sapiens];NP_055385.3//ADP-ribosylation factor GTPase-activating protein 3 isoform 1 [Homo sapiens]","4;1//3"]
[2125,6631,7.84,5.66,-0.470051601283326,{"v":2.56061247901235e-07,"d":"2.56E-07"},"*",{"v":3.89526e-08,"d":"3.90E-08"},"EVPL","GO:0005856//cytoskeleton;GO:0070062//extracellular exosome;GO:0045111//intermediate filament cytoskeleton;GO:0005829//cytosol;GO:0001533//cornified envelope;GO:0030057//desmosome","GO:0030674//protein binding, bridging;GO:0005198//structural molecule activity;GO:0019215//intermediate filament binding;GO:0045296//cadherin binding","GO:0018149//peptide cross-linking;GO:0008544//epidermis development;GO:0030216//keratinocyte differentiation;GO:0070268//cornification","K10383//envoplakin","NP_001979.2//envoplakin isoform 2 [Homo sapiens];NP_001307676.1//envoplakin isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[55293,2589,12.79,9.24,-0.469051507465579,{"v":1.72621619817851e-06,"d":"1.73E-06"},"*",{"v":2.96636e-07,"d":"2.97E-07"},"UEVLD","GO:0070062//extracellular exosome","GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor","GO:0019752//carboxylic acid metabolic process;GO:0006464//cellular protein modification process;GO:0005975//carbohydrate metabolic process;GO:0015031//protein transport","K00016//L-lactate dehydrogenase [EC:1.1.1.27];K01064//wingless-type MMTV integration site family, member 9;K12183//ESCRT-I complex subunit TSG101","XP_010349043.1//PREDICTED: ubiquitin-conjugating enzyme E2 variant 3 isoform X4 [Saimiri boliviensis boliviensis];NP_060784.3//ubiquitin-conjugating enzyme E2 variant 3 isoform b [Homo sapiens];NP_001248315.1//ubiquitin-conjugating enzyme E2 variant 3 isoform g [Homo sapiens];XP_008002998.1//PREDICTED: ubiquitin-conjugating enzyme E2 variant 3 isoform X10 [Chlorocebus sabaeus];NP_001248311.1//ubiquitin-conjugating enzyme E2 variant 3 isoform c [Homo sapiens];XP_008002941.1//PREDICTED: ubiquitin-conjugating enzyme E2 variant 3 isoform X3 [Chlorocebus sabaeus];XP_008002931.1//PREDICTED: ubiquitin-conjugating enzyme E2 variant 3 isoform X2 [Chlorocebus sabaeus];XP_008002973.1//PREDICTED: ubiquitin-conjugating enzyme E2 variant 3 isoform X7 [Chlorocebus sabaeus]","3//A2MP1;2//1;5"]
[678,3702,23.58,17.04,-0.468638382753924,{"v":3.17431780568407e-11,"d":"3.17E-11"},"*",{"v":3.0066e-12,"d":"3.01E-12"},"ZFP36L2","GO:0005634//nucleus;GO:0030529//intracellular ribonucleoprotein complex;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0017091//AU-rich element binding;GO:0035925//mRNA 3'-UTR AU-rich region binding;GO:0003700//DNA binding transcription factor activity","GO:0048103//somatic stem cell division;GO:0071385//cellular response to glucocorticoid stimulus;GO:0033077//T cell differentiation in thymus;GO:0035019//somatic stem cell population maintenance;GO:0071356//cellular response to tumor necrosis factor;GO:1900153//positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0070371//ERK1 and ERK2 cascade;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0008283//cell proliferation;GO:0060216//definitive hemopoiesis;GO:0043488//regulation of mRNA stability;GO:0030097//hemopoiesis;GO:0009611//response to wounding;GO:0045577//regulation of B cell differentiation;GO:1904628//cellular response to phorbol 13-acetate 12-myristate;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0045599//negative regulation of fat cell differentiation;GO:1901991//negative regulation of mitotic cell cycle phase transition;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0006402//mRNA catabolic process;GO:2000737//negative regulation of stem cell differentiation;GO:0061158//3'-UTR-mediated mRNA destabilization;GO:0097011//cellular response to granulocyte macrophage colony-stimulating factor stimulus","K18753//butyrate response factor","NP_008818.3//mRNA decay activator protein ZFP36L2 [Homo sapiens]",4]
[2035,5734,5.31,3.84,-0.467605550082997,0.000269727010351759,"*",{"v":6.72038e-05,"d":"6.72E-05"},"EPB41","GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0099738//cell cortex region;GO:0030054//cell junction;GO:0014069//postsynaptic density;GO:0030863//cortical cytoskeleton;GO:0014731//spectrin-associated cytoskeleton;GO:0043234//protein complex;GO:0005829//cytosol;GO:0009898//cytoplasmic side of plasma membrane;GO:0005886//plasma membrane","GO:0047485//protein N-terminus binding;GO:0005545//1-phosphatidylinositol binding;GO:0005200//structural constituent of cytoskeleton;GO:0003779//actin binding;GO:0008022//protein C-terminus binding;GO:0005198//structural molecule activity;GO:0005516//calmodulin binding;GO:0051219//phosphoprotein binding;GO:0030507//spectrin binding","GO:0006810//transport;GO:0031032//actomyosin structure organization;GO:0030036//actin cytoskeleton organization;GO:0030866//cortical actin cytoskeleton organization;GO:0008360//regulation of cell shape;GO:0032092//positive regulation of protein binding;GO:1904778//positive regulation of protein localization to cell cortex;GO:0051301//cell division;GO:0007049//cell cycle;GO:0006461//protein complex assembly","K06107//erythrocyte membrane protein band 4.1","XP_007977938.1//PREDICTED: protein 4.1 isoform X25 [Chlorocebus sabaeus];XP_009450495.1//PREDICTED: protein 4.1 isoform X21 [Pan troglodytes];XP_003271766.1//PREDICTED: protein 4.1 isoform X2 [Nomascus leucogenys];NP_001159477.1//protein 4.1 isoform 1 [Homo sapiens];NP_976218.1//protein 4.1 isoform 2 [Homo sapiens];BAD92886.1//Protein 4.1 variant, partial [Homo sapiens]","1//3;3//A2MP1;2//1"]
[256987,5178,4.13,2.99,-0.46599629722134,{"v":2.60383376100629e-05,"d":"2.60E-05"},"*",{"v":5.44272e-06,"d":"5.44E-06"},"SERINC5","GO:0070062//extracellular exosome;GO:0005794//Golgi apparatus;GO:0043209//myelin sheath;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0048471//perinuclear region of cytoplasm","GO:0015194//L-serine transmembrane transporter activity","GO:0042552//myelination;GO:0006658//phosphatidylserine metabolic process;GO:0009597//detection of virus;GO:0051607//defense response to virus;GO:0016032//viral process;GO:1904222//positive regulation of serine C-palmitoyltransferase activity;GO:0008654//phospholipid biosynthetic process;GO:1904219//positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity;GO:0006665//sphingolipid metabolic process;GO:0006564//L-serine biosynthetic process;GO:0045087//innate immune response","K16316//serine/threonine-protein kinase 31 [EC:2.7.11.1];K04175//C-X-C chemokine receptor type 1;K12025//tripartite motif-containing protein 52","NP_840060.1//serine incorporator 5 isoform 2 [Homo sapiens];NP_001167543.1//serine incorporator 5 isoform 1 [Homo sapiens];NP_001167542.1//serine incorporator 5 isoform 3 [Homo sapiens]","6;2//1"]
[116064,7683,11.24,8.14,-0.465541335954679,{"v":4.64469187540558e-11,"d":"4.64E-11"},"*",{"v":4.4807e-12,"d":"4.48E-12"},"LRRC58","NA","NA","NA","K17985//activating molecule in BECN1-regulated autophagy protein 1","AAH13757.1//LRRC58 protein, partial [Homo sapiens]","1//3"]
[201475,2138,16.65,12.07,-0.464096501203603,{"v":5.21890087105039e-05,"d":"5.22E-05"},"*",{"v":1.14774E-5,"d":"1.15E-05"},"RAB12","GO:0055038//recycling endosome membrane;GO:0005764//lysosome;GO:0005776//autophagosome","GO:0019003//GDP binding;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0016239//positive regulation of macroautophagy;GO:0044257//cellular protein catabolic process;GO:0008333//endosome to lysosome transport","K07907//Ras-related protein Rab-12","XP_007972827.1//PREDICTED: ras-related protein Rab-12 [Chlorocebus sabaeus]","2//1"]
[253260,9518,4.66,3.38,-0.463306708372096,{"v":3.68144616949153e-06,"d":"3.68E-06"},"*",{"v":6.66274E-7,"d":"6.66E-07"},"RICTOR","GO:0031932//TORC2 complex;GO:0005829//cytosol","GO:0043022//ribosome binding;GO:0008047//enzyme activator activity;GO:0019901//protein kinase binding","GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0042325//regulation of phosphorylation;GO:0010468//regulation of gene expression;GO:0051897//positive regulation of protein kinase B signaling;GO:0051896//regulation of protein kinase B signaling;GO:0031295//T cell costimulation;GO:0033135//regulation of peptidyl-serine phosphorylation;GO:0032956//regulation of actin cytoskeleton organization;GO:0032008//positive regulation of TOR signaling;GO:0030950//establishment or maintenance of actin cytoskeleton polarity;GO:0001938//positive regulation of endothelial cell proliferation;GO:0030838//positive regulation of actin filament polymerization;GO:0031929//TOR signaling;GO:0031532//actin cytoskeleton reorganization;GO:0050727//regulation of inflammatory response;GO:0038111//interleukin-7-mediated signaling pathway;GO:0030010//establishment of cell polarity;GO:2000114//regulation of establishment of cell polarity;GO:0043087//regulation of GTPase activity;GO:0018105//peptidyl-serine phosphorylation;GO:0009790//embryo development;GO:0048015//phosphatidylinositol-mediated signaling","K08267//rapamycin-insensitive companion of mTOR","NP_689969.2//rapamycin-insensitive companion of mTOR isoform 1 [Homo sapiens];XP_006714526.1//PREDICTED: rapamycin-insensitive companion of mTOR isoform X5 [Homo sapiens];NP_001272368.1//rapamycin-insensitive companion of mTOR isoform 2 [Homo sapiens]","4;1//3"]
[57179,2675,45.35,32.91,-0.462576524291536,{"v":7.93783050666667e-16,"d":"7.94E-16"},"*",{"v":5.21768e-17,"d":"5.22E-17"},"KIAA1191","GO:0005737//cytoplasm","GO:0016491//oxidoreductase activity","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K04613//vomeronasal 2 receptor;K01064//wingless-type MMTV integration site family, member 9","BAB14957.1//unnamed protein product [Homo sapiens];NP_065177.2//putative monooxygenase p33MONOX isoform a [Homo sapiens]","4;1//3;2//1"]
[84945,5316,2.41,1.75,-0.461678224397633,0.0234372785735318,"*",0.00896908,"ABHD13","NA","NA","NA","K06889//uncharacterized protein","XP_021785455.1//protein ABHD13 isoform X1 [Papio anubis]","2//1"]
[6309,6976,4.79,3.48,-0.460938349887452,{"v":7.15281505869263e-05,"d":"7.15E-05"},"*",{"v":1.609764e-05,"d":"1.61E-05"},"SC5D","GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0005506//iron ion binding;GO:0000248//C-5 sterol desaturase activity;GO:0050046//lathosterol oxidase activity;GO:0016491//oxidoreductase activity","GO:0033490//cholesterol biosynthetic process via lathosterol;GO:0033489//cholesterol biosynthetic process via desmosterol;GO:0008610//lipid biosynthetic process;GO:0045540//regulation of cholesterol biosynthetic process;GO:0006629//lipid metabolic process","K00227//Delta7-sterol 5-desaturase [EC:1.14.19.20]","NP_008849.2//lathosterol oxidase [Homo sapiens]","4;2//1"]
[81566,4603,6.48,4.71,-0.460266753271842,2.38861763410302E-4,"*",{"v":5.89304e-05,"d":"5.89E-05"},"CSRNP2","GO:0005634//nucleus","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0019902//phosphatase binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0010923//negative regulation of phosphatase activity;GO:0006915//apoptotic process","K17494//cysteine/serine-rich nuclear protein","NP_110436.1//cysteine/serine-rich nuclear protein 2 [Homo sapiens]","2//1"]
[128553,11671,0.22,0.16,-0.459431618637297,0.314920515957895,"*",0.1872884,"TSHZ2","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007275//multicellular organism development;GO:0006351//transcription, DNA-templated","K09236//teashirt","NP_001180350.1//teashirt homolog 2 isoform 2 [Homo sapiens];NP_775756.3//teashirt homolog 2 isoform 1 [Homo sapiens]","1//3;5"]
[117247,2918,0.11,0.08,-0.459431618637297,0.812279572086532,"*",0.728682,"SLC16A10","GO:0016323//basolateral plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0015349//thyroid hormone transmembrane transporter activity;GO:0008028//monocarboxylic acid transmembrane transporter activity;GO:0015173//aromatic amino acid transmembrane transporter activity;GO:0015171//amino acid transmembrane transporter activity","GO:0006865//amino acid transport;GO:0015801//aromatic amino acid transport","K08187//MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 10","NP_061063.2//monocarboxylate transporter 10 [Homo sapiens]",4]
[64965,1473,17.54,12.76,-0.459020418679864,0.000822802652114598,"*",2.26536E-4,"MRPS9","GO:0005840//ribosome;GO:0005730//nucleolus;GO:0005763//mitochondrial small ribosomal subunit;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome","GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006412//translation;GO:0070126//mitochondrial translational termination;GO:0042769//DNA damage response, detection of DNA damage;GO:0070125//mitochondrial translational elongation","K02996//small subunit ribosomal protein S9","NP_872578.1//28S ribosomal protein S9, mitochondrial [Homo sapiens]","2//1"]
[54870,3164,33.08,24.08,-0.458123842411573,{"v":5.88756e-13,"d":"5.89E-13"},"*",{"v":4.8246e-14,"d":"4.82E-14"},"QRICH1","GO:0005654//nucleoplasm;GO:0005737//cytoplasm","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0003677//DNA binding","GO:0007275//multicellular organism development;GO:0007010//cytoskeleton organization;GO:0022604//regulation of cell morphogenesis","K09187//histone-lysine N-methyltransferase MLL2 [EC:2.1.1.43];K17335//nuclear factor of activated T-cells 5","NP_060200.2//glutamine-rich protein 1 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[1786,5373,28.71,20.91,-0.457360268617602,{"v":1.57269602325581e-18,"d":"1.57E-18"},"*",{"v":8.467e-20,"d":"8.47E-20"},"DNMT1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005721//pericentric heterochromatin;GO:0005657//replication fork","GO:0003723//RNA binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0008270//zinc ion binding;GO:1990841//promoter-specific chromatin binding;GO:0003886//DNA (cytosine-5-)-methyltransferase activity;GO:0009008//DNA-methyltransferase activity;GO:0008327//methyl-CpG binding","GO:0051571//positive regulation of histone H3-K4 methylation;GO:0010216//maintenance of DNA methylation;GO:0016458//gene silencing;GO:0042127//regulation of cell proliferation;GO:0006351//transcription, DNA-templated;GO:0090309//positive regulation of methylation-dependent chromatin silencing;GO:0010628//positive regulation of gene expression;GO:0006306//DNA methylation;GO:0043045//DNA methylation involved in embryo development;GO:0071230//cellular response to amino acid stimulus;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0016569//covalent chromatin modification;GO:0045814//negative regulation of gene expression, epigenetic;GO:0051573//negative regulation of histone H3-K9 methylation;GO:0007265//Ras protein signal transduction","K00558//DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]","NP_001124295.1//DNA (cytosine-5)-methyltransferase 1 isoform a [Homo sapiens];XP_512361.4//PREDICTED: DNA (cytosine-5)-methyltransferase 1 isoform X2 [Pan troglodytes];XP_016790461.1//PREDICTED: DNA (cytosine-5)-methyltransferase 1 isoform X6 [Pan troglodytes];EAW84079.1//DNA (cytosine-5-)-methyltransferase 1, isoform CRA_a [Homo sapiens]","1//3;3//A2MP1;2//1"]
[5868,2533,18.24,13.29,-0.456764624888567,{"v":2.80510412108413e-06,"d":"2.81E-06"},"*",{"v":4.98892e-07,"d":"4.99E-07"},"RAB5A","GO:0010008//endosome membrane;GO:0030425//dendrite;GO:0042470//melanosome;GO:0005737//cytoplasm;GO:0043025//neuronal cell body;GO:0045335//phagocytic vesicle;GO:0097443//sorting endosome;GO:0098559//cytoplasmic side of early endosome membrane;GO:0005829//cytosol;GO:0030665//clathrin-coated vesicle membrane;GO:0015629//actin cytoskeleton;GO:0043679//axon terminus;GO:0005886//plasma membrane;GO:0005769//early endosome;GO:0070382//exocytic vesicle;GO:0070062//extracellular exosome;GO:0030424//axon;GO:0036477//somatodendritic compartment;GO:0008021//synaptic vesicle;GO:0030670//phagocytic vesicle membrane;GO:0043195//terminal bouton;GO:0005768//endosome;GO:0001726//ruffle;GO:0031901//early endosome membrane;GO:0030139//endocytic vesicle;GO:0045121//membrane raft;GO:0005811//lipid droplet","GO:0019003//GDP binding;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0043687//post-translational protein modification;GO:0036465//synaptic vesicle recycling;GO:0045022//early endosome to late endosome transport;GO:0007596//blood coagulation;GO:0030100//regulation of endocytosis;GO:0006661//phosphatidylinositol biosynthetic process;GO:0045921//positive regulation of exocytosis;GO:2000286//receptor internalization involved in canonical Wnt signaling pathway;GO:0006897//endocytosis;GO:0015031//protein transport;GO:0051489//regulation of filopodium assembly;GO:0006909//phagocytosis;GO:2000785//regulation of autophagosome assembly;GO:2000300//regulation of synaptic vesicle exocytosis;GO:0051036//regulation of endosome size;GO:0061024//membrane organization;GO:0039694//viral RNA genome replication;GO:0045056//transcytosis","K07887//Ras-related protein Rab-5A","NP_001278977.1//ras-related protein Rab-5A isoform 2 [Homo sapiens];NP_004153.2//ras-related protein Rab-5A isoform 1 [Homo sapiens]","1//3;4"]
[55208,3046,5.31,3.87,-0.456378294659743,0.0101446876892502,"*",0.00351514,"DCUN1D2","GO:0000151//ubiquitin ligase complex","GO:0032182//ubiquitin-like protein binding;GO:0097602//cullin family protein binding;GO:0031624//ubiquitin conjugating enzyme binding","GO:0045116//protein neddylation;GO:0051443//positive regulation of ubiquitin-protein transferase activity","K17822//DCN1-like protein 1/2","NP_001014305.1//DCN1-like protein 2 [Homo sapiens]","1//3"]
[9725,4469,3.47,2.53,-0.455798277883951,0.0119424990526876,"*",0.00421434,"TMEM63A","GO:0005765//lysosomal membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0005815//microtubule organizing center;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane;GO:0005886//plasma membrane;GO:0070821//tertiary granule membrane","GO:0003676//nucleic acid binding","GO:0043312//neutrophil degranulation;GO:0006811//ion transport","K21989//calcium permeable stress-gated cation channel","BAD96654.1//Hypothetical protein KIAA0792 (Novel protein) variant, partial [Homo sapiens]","2//1"]
[26056,4362,19.19,14,-0.454927884363051,{"v":2.61967877970149e-10,"d":"2.62E-10"},"*",{"v":2.74694e-11,"d":"2.75E-11"},"RAB11FIP5","GO:0030658//transport vesicle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005815//microtubule organizing center;GO:0005741//mitochondrial outer membrane;GO:0000139//Golgi membrane;GO:0030141//secretory granule;GO:0055038//recycling endosome membrane;GO:0031901//early endosome membrane;GO:0005794//Golgi apparatus;GO:0005769//early endosome;GO:0055037//recycling endosome","GO:0043015//gamma-tubulin binding;GO:0017137//Rab GTPase binding","GO:2000008//regulation of protein localization to cell surface;GO:0035773//insulin secretion involved in cellular response to glucose stimulus;GO:0045055//regulated exocytosis;GO:0070164//negative regulation of adiponectin secretion;GO:0071468//cellular response to acidic pH","K12484//Rab11 family-interacting protein 1/2/5","NP_056285.1//rab11 family-interacting protein 5 [Homo sapiens]","2//1"]
[10845,4788,13.35,9.75,-0.453365617937943,{"v":5.38825676122083E-8,"d":"5.39E-08"},"*",{"v":7.51536e-09,"d":"7.52E-09"},"CLPX","GO:0005759//mitochondrial matrix;GO:0005654//nucleoplasm;GO:0042645//mitochondrial nucleoid;GO:0009841//mitochondrial endopeptidase Clp complex;GO:0005829//cytosol;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0009368//endopeptidase Clp complex","GO:0016504//peptidase activator activity;GO:0046872//metal ion binding;GO:0005524//ATP binding;GO:0051082//unfolded protein binding;GO:0004176//ATP-dependent peptidase activity;GO:0016887//ATPase activity","GO:0006457//protein folding;GO:0046034//ATP metabolic process;GO:0006508//proteolysis;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0030163//protein catabolic process","K03544//ATP-dependent Clp protease ATP-binding subunit ClpX","NP_006651.2//ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial precursor [Homo sapiens]",4]
[23251,6742,0.26,0.19,-0.452512204697507,0.493386526583659,"*",0.339848,"KIAA1024","GO:0016021//integral component of membrane","NA","NA","K08631//a disintegrin and metalloproteinase with thrombospondin motifs 17 [EC:3.4.24.-]","NP_056021.1//UPF0258 protein KIAA1024 [Homo sapiens]","2//1"]
[60592,1882,14.64,10.7,-0.452304756995533,0.000629056716044776,"*",0.0001688616,"SCOC","GO:0005768//endosome;GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005802//trans-Golgi network;GO:0000139//Golgi membrane","NA","GO:0016239//positive regulation of macroautophagy;GO:0061635//regulation of protein complex stability","K20316//short coiled-coil protein","NP_001147135.1//short coiled-coil protein isoform 2 [Homo sapiens];NP_001147024.1//short coiled-coil protein isoform 3 [Homo sapiens];NP_001147107.1//short coiled-coil protein isoform 5 [Homo sapiens];NP_115936.2//short coiled-coil protein isoform 4 [Homo sapiens];NP_001146956.1//short coiled-coil protein isoform 1 [Homo sapiens];NP_001147162.1//short coiled-coil protein isoform 6 [Homo sapiens]","1//3;2//1"]
[144608,1139,1.08,0.79,-0.451106753986366,0.602420930011862,"*",0.445084,"C12orf60","NA","NA","NA","NA","XP_003265586.2//PREDICTED: uncharacterized protein C12orf60 homolog [Nomascus leucogenys]","3//A2MP1"]
[1185,5647,4.85,3.55,-0.450165722682445,0.000601593559344262,"*",1.608116E-4,"CLCN6","GO:0005765//lysosomal membrane;GO:0010008//endosome membrane;GO:0016021//integral component of membrane","GO:0005524//ATP binding;GO:0005247//voltage-gated chloride channel activity;GO:0015297//antiporter activity","GO:0009612//response to mechanical stimulus;GO:0006884//cell volume homeostasis;GO:0007165//signal transduction;GO:0006821//chloride transport;GO:0034220//ion transmembrane transport;GO:1902476//chloride transmembrane transport","K05015//chloride channel 6","NP_001243888.1//chloride transport protein 6 isoform 2 [Homo sapiens];NP_001277.1//chloride transport protein 6 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[55676,4969,13.61,9.97,-0.449001657105799,{"v":1.75042132188841e-08,"d":"1.75E-08"},"*",{"v":2.29788e-09,"d":"2.30E-09"},"SLC30A6","GO:0016020//membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0008324//cation transmembrane transporter activity;GO:0005385//zinc ion transmembrane transporter activity","GO:0010043//response to zinc ion;GO:0061088//regulation of sequestering of zinc ion","K14693//solute carrier family 30 (zinc transporter), member 6","NP_001180442.1//zinc transporter 6 isoform 1 [Homo sapiens];XP_016803799.1//PREDICTED: zinc transporter 6 isoform X9 [Pan troglodytes];NP_001180443.1//zinc transporter 6 isoform 3 [Homo sapiens];NP_001180444.1//zinc transporter 6 isoform 4 [Homo sapiens];NP_060434.2//zinc transporter 6 isoform 2 [Homo sapiens]","4;1//3;2//1"]
[55023,11987,2.17,1.59,-0.448668277160124,0.000791225759195796,"*",0.000216802,"PHIP","GO:0070062//extracellular exosome;GO:0005634//nucleus","GO:0070577//lysine-acetylated histone binding;GO:0005158//insulin receptor binding","GO:0008286//insulin receptor signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0008360//regulation of cell shape;GO:0045893//positive regulation of transcription, DNA-templated;GO:0043568//positive regulation of insulin-like growth factor receptor signaling pathway;GO:0001932//regulation of protein phosphorylation;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007010//cytoskeleton organization;GO:0022604//regulation of cell morphogenesis;GO:0045840//positive regulation of mitotic nuclear division;GO:0008284//positive regulation of cell proliferation","K11797//PH-interacting protein","NP_060404.4//PH-interacting protein [Homo sapiens]",6]
[65267,11356,0.15,0.11,-0.447458976971221,0.478575887096774,"*",0.32692,"WNK3","GO:0005829//cytosol;GO:0005923//bicellular tight junction;GO:0005737//cytoplasm;GO:0005912//adherens junction","GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0019869//chloride channel inhibitor activity","GO:2000021//regulation of ion homeostasis;GO:0035556//intracellular signal transduction;GO:0090279//regulation of calcium ion import;GO:1903078//positive regulation of protein localization to plasma membrane;GO:0072659//protein localization to plasma membrane;GO:0006468//protein phosphorylation;GO:0043066//negative regulation of apoptotic process;GO:2000651//positive regulation of sodium ion transmembrane transporter activity;GO:0010765//positive regulation of sodium ion transport;GO:0046777//protein autophosphorylation;GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:0032414//positive regulation of ion transmembrane transporter activity;GO:2000682//positive regulation of rubidium ion transport;GO:0090188//negative regulation of pancreatic juice secretion;GO:2000688//positive regulation of rubidium ion transmembrane transporter activity;GO:0051928//positive regulation of calcium ion transport","K08867//WNK lysine deficient protein kinase [EC:2.7.11.1]","NP_065973.2//serine/threonine-protein kinase WNK3 isoform 1 [Homo sapiens];NP_001002838.1//serine/threonine-protein kinase WNK3 isoform 2 [Homo sapiens]","4;3//A2MP1"]
[22916,2249,15.16,11.12,-0.447112965447584,{"v":3.15719973388284e-05,"d":"3.16E-05"},"*",{"v":6.71404e-06,"d":"6.71E-06"},"NCBP2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005845//mRNA cap binding complex;GO:0034518//RNA cap binding complex;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005846//nuclear cap binding complex","GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0000339//RNA cap binding;GO:0000340//RNA 7-methylguanosine cap binding;GO:0017069//snRNA binding","GO:0006406//mRNA export from nucleus;GO:0008334//histone mRNA metabolic process;GO:0042795//snRNA transcription from RNA polymerase II promoter;GO:0006408//snRNA export from nucleus;GO:0006370//7-methylguanosine mRNA capping;GO:0006369//termination of RNA polymerase II transcription;GO:0045292//mRNA cis splicing, via spliceosome;GO:0031124//mRNA 3'-end processing;GO:0006405//RNA export from nucleus;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0098789//pre-mRNA cleavage required for polyadenylation;GO:0051168//nuclear export;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0016070//RNA metabolic process;GO:0000398//mRNA splicing, via spliceosome;GO:0046833//positive regulation of RNA export from nucleus;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0031047//gene silencing by RNA;GO:0006366//transcription from RNA polymerase II promoter;GO:0006446//regulation of translational initiation;GO:0031442//positive regulation of mRNA 3'-end processing;GO:0008380//RNA splicing","K12883//nuclear cap-binding protein subunit 2","NP_001036005.1//nuclear cap-binding protein subunit 2 isoform 2 [Homo sapiens];XP_008007826.1//PREDICTED: nuclear cap-binding protein subunit 2 isoform X2 [Chlorocebus sabaeus];NP_001294965.1//nuclear cap-binding protein subunit 2 isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[55691,5972,1.09,0.8,-0.446256229889564,0.256552280968097,"*",0.145991,"FRMD4A","GO:0005856//cytoskeleton;GO:0005923//bicellular tight junction;GO:0005737//cytoplasm;GO:0005912//adherens junction","GO:0030674//protein binding, bridging","GO:0090162//establishment of epithelial cell polarity","K10955//mucin-2;K12817//pre-mRNA-splicing factor 18;K05762//radixin;K16684//merlin;K21125//mucin-5AC;K05763//moesin","XP_015311068.1//PREDICTED: FERM domain-containing protein 4A isoform X11 [Macaca fascicularis];XP_008000516.1//PREDICTED: FERM domain-containing protein 4A isoform X3 [Chlorocebus sabaeus];XP_005252546.1//PREDICTED: FERM domain-containing protein 4A isoform X9 [Homo sapiens];XP_016871883.1//PREDICTED: FERM domain-containing protein 4A isoform X12 [Homo sapiens]","4;1//3"]
[54882,7501,6.64,4.88,-0.444302093784038,{"v":6.89336496247582e-07,"d":"6.89E-07"},"*",{"v":1.115522E-7,"d":"1.12E-07"},"ANKHD1","NA","NA","NA","K16726//ankyrin repeat domain-containing protein 17","NP_060217.1//ankyrin repeat and KH domain-containing protein 1 isoform 1 [Homo sapiens];EHH54586.1//hypothetical protein EGM_15457 [Macaca fascicularis]","1//3;3//A2MP1;2//1"]
[55055,3181,20.26,14.89,-0.444290420219038,{"v":5.91612266012489e-08,"d":"5.92E-08"},"*",{"v":8.30346e-09,"d":"8.30E-09"},"ZWILCH","GO:1990423//RZZ complex;GO:0005829//cytosol;GO:0000776//kinetochore;GO:0000777//condensed chromosome kinetochore","NA","GO:0007093//mitotic cell cycle checkpoint;GO:0007062//sister chromatid cohesion;GO:0051301//cell division","K11579//protein zwilch","NP_060445.3//protein zwilch homolog isoform 1 [Homo sapiens];XP_009248219.1//PREDICTED: protein zwilch homolog isoform X2 [Pongo abelii]","4;1//3"]
[23099,5903,2.42,1.78,-0.443129806308197,0.0213957495349992,"*",0.00809406,"ZBTB43","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K10514//zinc finger and BTB domain-containing protein 43","XP_012627394.1//zinc finger and BTB domain-containing protein 43 isoform X1 [Microcebus murinus];ELK07206.1//Zinc finger and BTB domain-containing protein 43 [Pteropus alecto]","1//3;3//A2MP1"]
[2618,3012,30.74,22.62,-0.442518235700951,{"v":1.4559162815546e-10,"d":"1.46E-10"},"*",{"v":1.477426e-11,"d":"1.48E-11"},"GART","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0005524//ATP binding;GO:0004641//phosphoribosylformylglycinamidine cyclo-ligase activity;GO:0004637//phosphoribosylamine-glycine ligase activity;GO:0004644//phosphoribosylglycinamide formyltransferase activity","GO:0021549//cerebellum development;GO:0009113//purine nucleobase biosynthetic process;GO:0006189//'de novo' IMP biosynthetic process;GO:0021987//cerebral cortex development;GO:0046654//tetrahydrofolate biosynthetic process;GO:0010035//response to inorganic substance;GO:0010033//response to organic substance;GO:0006544//glycine metabolic process;GO:0003360//brainstem development;GO:0009168//purine ribonucleoside monophosphate biosynthetic process","K11787//phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.4.13 2.1.2.2 6.3.3.1]","XP_003927696.1//PREDICTED: trifunctional purine biosynthetic protein adenosine-3 isoform X1 [Saimiri boliviensis boliviensis];BAD92022.1//phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase isoform 1 variant, partial [Homo sapiens]","4;1//3;2//1"]
[1629,10831,1.78,1.31,-0.442310429428947,0.0052994107134864,"*",0.001719472,"DBT","GO:0042645//mitochondrial nucleoid","GO:0016746//transferase activity, transferring acyl groups;GO:0031625//ubiquitin protein ligase binding","GO:0008152//metabolic process","K09699//2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase) [EC:2.3.1.168]","AAA35589.1//branched chain acyltransferase precursor [Homo sapiens]","3//A2MP1"]
[9373,4908,11.05,8.14,-0.440945670012547,{"v":1.12668912364587E-6,"d":"1.13E-06"},"*",{"v":1.88816e-07,"d":"1.89E-07"},"PLAA","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0043130//ubiquitin binding;GO:0016005//phospholipase A2 activator activity","GO:0007165//signal transduction;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0006644//phospholipid metabolic process;GO:0010992//ubiquitin recycling;GO:0016236//macroautophagy;GO:0006954//inflammatory response","K14018//phospholipase A-2-activating protein","NP_001308475.1//phospholipase A-2-activating protein isoform 2 [Homo sapiens];XP_002819776.1//PREDICTED: phospholipase A-2-activating protein [Pongo abelii]","1//3;2//1"]
[9883,6087,38.04,28.04,-0.44003089684994,{"v":1.5934896017341E-21,"d":"1.59E-21"},"*",{"v":6.90306e-23,"d":"6.90E-23"},"POM121","NA","NA","NA","K14316//nuclear pore complex protein Nup121","XP_009441437.2//PREDICTED: nuclear envelope pore membrane protein POM 121C isoform X1 [Pan troglodytes]","4;2//1"]
[11179,2687,3.12,2.3,-0.439912167917873,0.0995219390803057,"*",0.0464714,"ZNF277","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:2000772//regulation of cellular senescence;GO:0070301//cellular response to hydrogen peroxide","K06245//laminin, beta 4;K12581//CCR4-NOT transcription complex subunit 7/8;K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K07575//PUA domain protein","XP_017734154.1//PREDICTED: zinc finger protein 277 isoform X1 [Rhinopithecus bieti]","2//1"]
[3161,2959,15.16,11.19,-0.438059717194698,{"v":7.47034917491749e-06,"d":"7.47E-06"},"*",{"v":1.417e-06,"d":"1.42E-06"},"HMMR","GO:0016020//membrane;GO:0009986//cell surface;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0005540//hyaluronic acid binding","GO:0010389//regulation of G2/M transition of mitotic cell cycle;GO:0030214//hyaluronan catabolic process","K06267//hyaluronan-mediated motility receptor","XP_003810951.1//PREDICTED: hyaluronan mediated motility receptor isoform X1 [Pan paniscus];XP_008961538.1//PREDICTED: hyaluronan mediated motility receptor isoform X2 [Pan paniscus];NP_001136029.1//hyaluronan mediated motility receptor isoform d [Homo sapiens]","1//3;2//1"]
[55922,3277,7.65,5.65,-0.437208880277464,1.44439756910393E-3,"*",0.000416754,"NKRF","GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005730//nucleolus","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003723//RNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0007165//signal transduction;GO:0045944//positive regulation of transcription from RNA polymerase II promoter","K13096//splicing factor 4;K13094//RNA-binding protein 5/10;K13166//splicing factor, arginine/serine-rich 14","NP_001166958.1//NF-kappa-B-repressing factor isoform 1 [Homo sapiens];XP_008017613.1//PREDICTED: NF-kappa-B-repressing factor [Chlorocebus sabaeus]","1//3;3//A2MP1"]
[29083,1364,6.85,5.06,-0.436966603153579,0.0783425931840312,"*",0.0352576,"GTPBP8","GO:0005739//mitochondrion","GO:0046872//metal ion binding;GO:0005525//GTP binding","NA","NA","NP_054889.2//GTP-binding protein 8 isoform 1 [Homo sapiens];NP_612494.1//GTP-binding protein 8 isoform 2 [Homo sapiens]","1//3;2//1"]
[51534,3371,14.57,10.77,-0.435982627520305,{"v":5.53551631946309e-06,"d":"5.54E-06"},"*",{"v":1.032668E-6,"d":"1.03E-06"},"VTA1","GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0010008//endosome membrane;GO:0005654//nucleoplasm;GO:0005829//cytosol","GO:0008022//protein C-terminus binding","GO:0016197//endosomal transport;GO:0046755//viral budding;GO:0071985//multivesicular body sorting pathway;GO:0019058//viral life cycle;GO:1904903//ESCRT III complex disassembly;GO:0036258//multivesicular body assembly;GO:0015031//protein transport;GO:0016236//macroautophagy","K12199//vacuolar protein sorting-associated protein VTA1","NP_001273300.1//vacuolar protein sorting-associated protein VTA1 homolog isoform b [Homo sapiens];NP_057569.2//vacuolar protein sorting-associated protein VTA1 homolog isoform a [Homo sapiens];NP_001273301.1//vacuolar protein sorting-associated protein VTA1 homolog isoform c [Homo sapiens]","4;1//3"]
[3305,2550,0.73,0.54,-0.434937056716549,0.506344737846597,"*",0.352102,"HSPA1L","NA","NA","NA","K03283//heat shock 70kDa protein 1/2/6/8","EAX03527.1//heat shock 70kDa protein 1-like [Homo sapiens]","3//A2MP1"]
[339263,7912,4.46,3.3,-0.434577685674489,1.29348680297398E-4,"*",{"v":3.0495e-05,"d":"3.05E-05"},"C17orf51","NA","NA","NA","K08798//MAP/microtubule affinity-regulating kinase [EC:2.7.11.1]","NP_001106905.1//uncharacterized protein C17orf51 [Homo sapiens]",4]
[205428,3604,3.77,2.79,-0.434299401439477,0.00805651648148148,"*",0.0027235,"C3orf58","GO:0005615//extracellular space;GO:0030126//COPI vesicle coat;GO:0000139//Golgi membrane","NA","GO:0060038//cardiac muscle cell proliferation;GO:0014066//regulation of phosphatidylinositol 3-kinase signaling","K17046//protein DEK;K16628//collagen, type VII, alpha;K02599//Notch 1","NP_775823.1//deleted in autism protein 1 isoform a precursor [Homo sapiens];NP_001127942.1//deleted in autism protein 1 isoform b [Homo sapiens]","1//3;3//A2MP1"]
[196294,777,9.55,7.07,-0.433790518113712,0.112170133105623,"*",0.0534518,"IMMP1L","NA","NA","NA","K09647//mitochondrial inner membrane protease subunit 1 [EC:3.4.21.-]","XP_008954127.1//PREDICTED: mitochondrial inner membrane protease subunit 1 isoform X2 [Pan paniscus];XP_008954126.1//PREDICTED: mitochondrial inner membrane protease subunit 1 isoform X1 [Pan paniscus]","1//3;2//1"]
[3775,2161,5.71,4.23,-0.432833082242893,0.0374120165903151,"*",0.01523508,"KCNK1","GO:0043231//intracellular membrane-bounded organelle;GO:0030425//dendrite;GO:0016324//apical plasma membrane;GO:1902937//inward rectifier potassium channel complex;GO:0031526//brush border membrane;GO:0030054//cell junction;GO:0043204//perikaryon;GO:0005768//endosome;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0045202//synapse;GO:0055037//recycling endosome;GO:0034705//potassium channel complex;GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex","GO:0005267//potassium channel activity;GO:0005242//inward rectifier potassium channel activity;GO:0042802//identical protein binding;GO:0005272//sodium channel activity;GO:0022841//potassium ion leak channel activity","GO:0035094//response to nicotine;GO:0006813//potassium ion transport;GO:0061337//cardiac conduction;GO:0035725//sodium ion transmembrane transport;GO:0030322//stabilization of membrane potential;GO:0071805//potassium ion transmembrane transport;GO:0060075//regulation of resting membrane potential","K04912//potassium channel subfamily K member 1","NP_002236.1//potassium channel subfamily K member 1 [Homo sapiens]","3//A2MP1"]
[2631,2017,29.98,22.23,-0.431492434920869,{"v":1.27861851941581e-07,"d":"1.28E-07"},"*",{"v":1.863418e-08,"d":"1.86E-08"},"NIPSNAP2","GO:0016020//membrane;GO:0005887//integral component of plasma membrane;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane","NA","GO:0006119//oxidative phosphorylation;GO:2000984//negative regulation of ATP citrate synthase activity;GO:0006754//ATP biosynthetic process;GO:1901843//positive regulation of high voltage-gated calcium channel activity","K13174//THO complex subunit 5;K19269//phosphoglycolate phosphatase [EC:3.1.3.18 3.1.3.48]","NP_001474.1//protein NipSnap homolog 2 isoform 1 [Homo sapiens];NP_001189398.1//protein NipSnap homolog 2 isoform 2 [Homo sapiens]","1//3;2//1"]
[83988,3586,0.89,0.66,-0.431339311607944,0.381480888176353,"*",0.238336,"NCALD","GO:0070062//extracellular exosome;GO:0030130//clathrin coat of trans-Golgi network vesicle;GO:0005829//cytosol;GO:0005622//intracellular","GO:0015276//ligand-gated ion channel activity;GO:0015631//tubulin binding;GO:0003779//actin binding;GO:0030276//clathrin binding;GO:0043014//alpha-tubulin binding;GO:0005509//calcium ion binding","GO:0003073//regulation of systemic arterial blood pressure;GO:0019722//calcium-mediated signaling;GO:0016192//vesicle-mediated transport","K19695//neurocalcin delta","NP_776823.1//neurocalcin-delta [Bos taurus]","1//3;2//1"]
[129450,5384,3.8,2.82,-0.430304255932154,6.04100060243717E-3,"*",1.986186E-3,"TYW5","GO:0005737//cytoplasm","GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;GO:0005506//iron ion binding;GO:0102524//tRNAPhe (7-(3-amino-3-carboxypropyl)wyosine37-C2)-hydroxylase activity;GO:0000049//tRNA binding;GO:0042803//protein homodimerization activity","GO:0006400//tRNA modification;GO:0031591//wybutosine biosynthetic process","K18066//tRNA wybutosine-synthesizing protein 5 [EC:1.14.11.42]","NP_001034782.1//tRNA wybutosine-synthesizing protein 5 [Homo sapiens]","2//1"]
[8645,3800,1.32,0.98,-0.429684275243245,0.234519506530749,"*",0.1310602,"KCNK5","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane","GO:0005249//voltage-gated potassium channel activity;GO:0005267//potassium channel activity;GO:0022841//potassium ion leak channel activity","GO:0006813//potassium ion transport;GO:0007588//excretion;GO:0071805//potassium ion transmembrane transport;GO:0030322//stabilization of membrane potential","K04916//potassium channel subfamily K member 5","NP_003731.1//potassium channel subfamily K member 5 [Homo sapiens]","3//A2MP1"]
[55568,5966,41.26,30.64,-0.429327523961527,{"v":7.60732899619772e-26,"d":"7.61E-26"},"*",{"v":2.50498E-27,"d":"2.50E-27"},"GALNT10","GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0004653//polypeptide N-acetylgalactosaminyltransferase activity;GO:0030246//carbohydrate binding","GO:0016266//O-glycan processing","K00710//polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41]","BAD21405.1//mFLJ00205 protein, partial [Mus musculus]","3//A2MP1"]
[23390,4609,3.31,2.46,-0.428172901467978,0.0158224940206186,"*",0.0057648,"ZDHHC17","GO:0043231//intracellular membrane-bounded organelle;GO:0030054//cell junction;GO:0030660//Golgi-associated vesicle membrane;GO:0000139//Golgi membrane;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0042734//presynaptic membrane;GO:0030659//cytoplasmic vesicle membrane","GO:0016409//palmitoyltransferase activity;GO:0042802//identical protein binding;GO:0004871//signal transducer activity;GO:0015095//magnesium ion transmembrane transporter activity;GO:0019706//protein-cysteine S-palmitoyltransferase activity","GO:0018345//protein palmitoylation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0042953//lipoprotein transport","K20032//palmitoyltransferase ZDHHC13/17 [EC:2.3.1.225]","XP_012297503.1//palmitoyltransferase ZDHHC17 [Aotus nancymaae];NP_056151.2//palmitoyltransferase ZDHHC17 [Homo sapiens]","1//3;3//A2MP1"]
[51068,2769,9.66,7.18,-0.428039345012722,0.00140072577535916,"*",0.000402838,"NMD3","GO:0016020//membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0030674//protein binding, bridging;GO:0043023//ribosomal large subunit binding","GO:0000055//ribosomal large subunit export from nucleus;GO:1902680//positive regulation of RNA biosynthetic process;GO:1904751//positive regulation of protein localization to nucleolus;GO:0015031//protein transport;GO:0032092//positive regulation of protein binding","K07562//nonsense-mediated mRNA decay protein 3","NP_057022.2//60S ribosomal export protein NMD3 isoform 2 [Homo sapiens];NP_001307156.1//60S ribosomal export protein NMD3 isoform 1 [Homo sapiens]","1//3;4"]
[79896,3787,2.93,2.18,-0.426572529645322,0.0508157859628428,"*",0.0215746,"THNSL1","NA","NA","NA","K06245//laminin, beta 4;K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K02927//large subunit ribosomal protein L40e;K15696//RING finger protein 113B;K17985//activating molecule in BECN1-regulated autophagy protein 1","NP_079114.3//threonine synthase-like 1 [Homo sapiens]",4]
[23299,5446,8.85,6.59,-0.425398989962308,{"v":3.74633150786607E-7,"d":"3.75E-07"},"*",{"v":5.81392E-8,"d":"5.81E-08"},"BICD2","GO:0005856//cytoskeleton;GO:0005643//nuclear pore;GO:0005635//nuclear envelope;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0031410//cytoplasmic vesicle;GO:0005642//annulate lamellae;GO:0005886//plasma membrane","GO:0051959//dynein light intermediate chain binding;GO:0070840//dynein complex binding;GO:0034452//dynactin binding;GO:0017137//Rab GTPase binding","GO:0051642//centrosome localization;GO:0000042//protein targeting to Golgi;GO:0072393//microtubule anchoring at microtubule organizing center;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0072385//minus-end-directed organelle transport along microtubule;GO:0051028//mRNA transport","K18739//protein bicaudal D","NP_001003800.1//protein bicaudal D homolog 2 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[5411,3606,26.99,20.1,-0.42522947540056,{"v":1.6229192720147e-10,"d":"1.62E-10"},"*",{"v":1.659088e-11,"d":"1.66E-11"},"PNN","NA","NA","NA","K13114//pinin","XP_019569216.1//PREDICTED: pinin [Rhinolophus sinicus]","3//A2MP1"]
[643338,2503,0.51,0.38,-0.42449782852791,0.617247559202814,"*",0.461448,"C15orf62","GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0017049//GTP-Rho binding;GO:0005096//GTPase activator activity","GO:0007266//Rho protein signal transduction;GO:0031274//positive regulation of pseudopodium assembly;GO:0030838//positive regulation of actin filament polymerization;GO:0008360//regulation of cell shape","NA","XP_003935755.1//PREDICTED: uncharacterized protein C15orf62 homolog, mitochondrial [Saimiri boliviensis boliviensis]","2//1"]
[11138,4232,18.81,14.02,-0.424013499512572,{"v":1.22311139659699e-08,"d":"1.22E-08"},"*",{"v":1.575022E-9,"d":"1.58E-09"},"TBC1D8","GO:0016020//membrane;GO:0012505//endomembrane system;GO:0005622//intracellular","GO:0017137//Rab GTPase binding;GO:0005096//GTPase activator activity","GO:0006886//intracellular protein transport;GO:0008015//blood circulation;GO:0090630//activation of GTPase activity;GO:0031338//regulation of vesicle fusion;GO:0008284//positive regulation of cell proliferation","K19951//TBC1 domain family member 8/9","NP_001317277.1//TBC1 domain family member 8 isoform 1 [Homo sapiens];NP_001095896.1//TBC1 domain family member 8 isoform 2 [Homo sapiens]","1//3;2//1"]
[146723,2525,0.59,0.44,-0.423211430724544,0.64677355594088,"*",0.490364,"C17orf77","GO:0005576//extracellular region","NA","NA","K16506//protocadherin Fat 1/2/3;K01368//cathepsin S [EC:3.4.22.27];K08857//NIMA (never in mitosis gene a)-related kinase 1/4/5 [EC:2.7.11.1]","NP_689673.2//uncharacterized protein C17orf77 [Homo sapiens]","1//3;2//1"]
[25853,3688,27.29,20.36,-0.422634833198445,{"v":9.90638533249686e-11,"d":"9.91E-11"},"*",{"v":9.8853e-12,"d":"9.89E-12"},"DCAF12","GO:0080008//Cul4-RING E3 ubiquitin ligase complex;GO:0005813//centrosome;GO:0005737//cytoplasm","NA","GO:0016567//protein ubiquitination","K11803//WD repeat-containing protein 40A","ELR51095.1//DDB1- and CUL4-associated factor 12, partial [Bos mutus]","3//A2MP1"]
[687,5208,0.67,0.5,-0.422233000683048,0.353884025043621,"*",0.215844,"KLF9","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0010839//negative regulation of keratinocyte proliferation;GO:0007623//circadian rhythm;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0071387//cellular response to cortisol stimulus;GO:0006351//transcription, DNA-templated;GO:0097067//cellular response to thyroid hormone stimulus","K09208//krueppel-like factor 9/13/14/16","NP_001197.1//Krueppel-like factor 9 [Homo sapiens]","2//1"]
[79786,7571,3.99,2.98,-0.421076415760184,0.000608976077606358,"*",0.00016309,"KLHL36","GO:0031463//Cul3-RING ubiquitin ligase complex","NA","GO:0016567//protein ubiquitination","K13958//kelch-like protein 36","NP_001290380.1//kelch-like protein 36 isoform 2 [Homo sapiens];XP_016785783.1//PREDICTED: kelch-like protein 36 isoform X3 [Pan troglodytes]","1//3;3//A2MP1"]
[24137,4504,13.33,9.97,-0.419011370690777,{"v":1.2285004375e-06,"d":"1.23E-06"},"*",{"v":2.06724e-07,"d":"2.07E-07"},"KIF4A","GO:0016020//membrane;GO:0045171//intercellular bridge;GO:0005654//nucleoplasm;GO:0030496//midbody;GO:0005871//kinesin complex","GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0008574//ATP-dependent microtubule motor activity, plus-end-directed","GO:0000281//mitotic cytokinesis;GO:0007018//microtubule-based movement;GO:0051256//mitotic spindle midzone assembly","K10395//kinesin family member 4/21/27","XP_007990177.1//PREDICTED: chromosome-associated kinesin KIF4A [Chlorocebus sabaeus]",4]
[91351,6667,2.46,1.84,-0.418952549282227,0.0190112034417981,"*",0.00709558,"DDX60L","NA","GO:0003723//RNA binding;GO:0005524//ATP binding;GO:0004386//helicase activity;GO:0003676//nucleic acid binding","NA","K20103//ATP-dependent RNA helicase DDX60 [EC:3.6.4.13]","NP_001278439.1//probable ATP-dependent RNA helicase DDX60-like isoform 2 [Homo sapiens];Q5H9U9.2//RecName: Full=Probable ATP-dependent RNA helicase DDX60-like; AltName: Full=DEAD box protein 60-like","1//3;2//1"]
[286075,2452,4.45,3.33,-0.418283158782498,0.0836733543172414,"*",0.0379762,"ZNF707","GO:0005622//intracellular","GO:0046872//metal ion binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","EGW13772.1//Zinc finger protein 623 [Cricetulus griseus]","1//3;3//A2MP1"]
[10057,4524,5.13,3.84,-0.417852514885898,0.000307474336293724,"*",{"v":7.75904e-05,"d":"7.76E-05"},"ABCC5","GO:0016020//membrane;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane","GO:0043225//ATPase-coupled anion transmembrane transporter activity;GO:0005524//ATP binding;GO:0042626//ATPase activity, coupled to transmembrane movement of substances;GO:0008514//organic anion transmembrane transporter activity","GO:0006810//transport;GO:0055085//transmembrane transport;GO:0030213//hyaluronan biosynthetic process","K05668//ATP-binding cassette, subfamily C (CFTR/MRP), member 5","XP_005546569.1//PREDICTED: multidrug resistance-associated protein 5 isoform X1 [Macaca fascicularis];NP_005679.2//multidrug resistance-associated protein 5 isoform 1 [Homo sapiens];XP_017721361.1//PREDICTED: multidrug resistance-associated protein 5-like isoform X2 [Rhinopithecus bieti]","1//3;3//A2MP1;2//1"]
[7039,4339,2.27,1.7,-0.417157551153213,0.0813594914728682,"*",0.0367936,"TGFA","GO:0016323//basolateral plasma membrane;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0031410//cytoplasmic vesicle;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0048471//perinuclear region of cytoplasm;GO:0000139//Golgi membrane;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0012507//ER to Golgi transport vesicle membrane","GO:0008083//growth factor activity;GO:0005154//epidermal growth factor receptor binding","GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0048208//COPII vesicle coating;GO:0051781//positive regulation of cell division;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0045840//positive regulation of mitotic nuclear division;GO:0042493//response to drug;GO:0000187//activation of MAPK activity;GO:0001525//angiogenesis;GO:0045741//positive regulation of epidermal growth factor-activated receptor activity;GO:0042060//wound healing;GO:0072574//hepatocyte proliferation;GO:0043066//negative regulation of apoptotic process;GO:0060749//mammary gland alveolus development;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0050679//positive regulation of epithelial cell proliferation;GO:0008284//positive regulation of cell proliferation","K08774//transforming growth factor, alpha","NP_001295088.1//protransforming growth factor alpha isoform 4 precursor [Homo sapiens];XP_007938333.1//PREDICTED: protransforming growth factor alpha [Orycteropus afer afer];NP_001295087.1//protransforming growth factor alpha isoform 3 precursor [Homo sapiens]","1//3;3//A2MP1;2//1"]
[4528,2665,16.11,12.07,-0.416530817951547,{"v":7.82003482333425e-05,"d":"7.82E-05"},"*",{"v":1.770694e-05,"d":"1.77E-05"},"MTIF2","GO:0005654//nucleoplasm;GO:0005739//mitochondrion","GO:0003743//translation initiation factor activity;GO:0008135//translation factor activity, RNA binding;GO:0003723//RNA binding;GO:0043024//ribosomal small subunit binding;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0006446//regulation of translational initiation;GO:0070124//mitochondrial translational initiation;GO:0032790//ribosome disassembly","K02519//translation initiation factor IF-2","XP_011812837.1//PREDICTED: translation initiation factor IF-2, mitochondrial [Colobus angolensis palliatus];NP_002444.2//translation initiation factor IF-2, mitochondrial isoform a precursor [Homo sapiens]","1//3;2//1"]
[8801,2363,14.81,11.1,-0.41601196405138,3.98408938222438E-4,"*",0.0001027074,"SUCLG2","GO:0005759//mitochondrial matrix;GO:0045244//succinate-CoA ligase complex (GDP-forming);GO:0005739//mitochondrion;GO:0005886//plasma membrane","GO:0004775//succinate-CoA ligase (ADP-forming) activity;GO:0000287//magnesium ion binding;GO:0005524//ATP binding;GO:0019003//GDP binding;GO:0046982//protein heterodimerization activity;GO:0046872//metal ion binding;GO:0005525//GTP binding;GO:0004776//succinate-CoA ligase (GDP-forming) activity","GO:0006099//tricarboxylic acid cycle;GO:0006104//succinyl-CoA metabolic process;GO:0006105//succinate metabolic process","K01900//succinyl-CoA synthetase beta subunit [EC:6.2.1.4 6.2.1.5]","NP_003839.2//succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial isoform 2 precursor [Homo sapiens];NP_001171070.1//succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[9254,5461,0.28,0.21,-0.415037499278844,0.56395981877918,"*",0.408336,"CACNA2D2","GO:0005886//plasma membrane;GO:0005891//voltage-gated calcium channel complex","GO:0046872//metal ion binding;GO:0005245//voltage-gated calcium channel activity","GO:0007528//neuromuscular junction development;GO:0046622//positive regulation of organ growth;GO:0061337//cardiac conduction;GO:0060024//rhythmic synaptic transmission;GO:0040014//regulation of multicellular organism growth;GO:0048747//muscle fiber development;GO:0050796//regulation of insulin secretion","K04859//voltage-dependent calcium channel alpha-2/delta-2","NP_001005505.1//voltage-dependent calcium channel subunit alpha-2/delta-2 isoform a precursor [Homo sapiens];XP_011737764.1//PREDICTED: voltage-dependent calcium channel subunit alpha-2/delta-2 isoform X1 [Macaca nemestrina];XP_011737765.1//PREDICTED: voltage-dependent calcium channel subunit alpha-2/delta-2 isoform X2 [Macaca nemestrina]","1//3;3//A2MP1;2//1"]
[4855,6762,0.04,0.03,-0.415037499278844,1.01600911900057,"*",0.997882,"NOTCH4","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000139//Golgi membrane;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane","GO:0004872//receptor activity;GO:0005509//calcium ion binding;GO:0046982//protein heterodimerization activity","GO:0006355//regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0001763//morphogenesis of a branching structure;GO:0030097//hemopoiesis;GO:0045602//negative regulation of endothelial cell differentiation;GO:0030879//mammary gland development;GO:0001709//cell fate determination;GO:0001886//endothelial cell morphogenesis;GO:0030154//cell differentiation;GO:0007221//positive regulation of transcription of Notch receptor target;GO:0007220//Notch receptor processing;GO:0007275//multicellular organism development;GO:0009790//embryo development;GO:0045596//negative regulation of cell differentiation;GO:0050793//regulation of developmental process;GO:0001569//branching involved in blood vessel morphogenesis;GO:0007219//Notch signaling pathway;GO:0006367//transcription initiation from RNA polymerase II promoter","K20996//Notch 4","NP_004548.3//neurogenic locus notch homolog protein 4 preproprotein [Homo sapiens]","3//A2MP1"]
[9940,5635,0.04,0.03,-0.415037499278844,0.782819122991611,"*",0.689316,"DLEC1","GO:0005829//cytosol;GO:0005737//cytoplasm","NA","GO:0008285//negative regulation of cell proliferation","K17570//hydrocephalus-inducing protein","NP_031361.2//deleted in lung and esophageal cancer protein 1 isoform DLEC1-N1 [Homo sapiens];NP_031363.2//deleted in lung and esophageal cancer protein 1 isoform DLEC1-S3 [Homo sapiens];NP_001308082.1//deleted in lung and esophageal cancer protein 1 isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[5669,1895,0.32,0.24,-0.415037499278844,0.582329381930185,"*",0.426084,"PSG1","GO:0005576//extracellular region","NA","GO:0007565//female pregnancy;GO:0050900//leukocyte migration","K06500//pregnancy specific beta-1-glycoprotein","NP_001284702.1//pregnancy-specific beta-1-glycoprotein 1 isoform 4 precursor [Homo sapiens];NP_001317453.1//pregnancy-specific beta-1-glycoprotein 1 isoform 5 precursor [Homo sapiens];NP_008836.2//pregnancy-specific beta-1-glycoprotein 1 isoform 1 precursor [Homo sapiens];NP_001171755.1//pregnancy-specific beta-1-glycoprotein 1 isoform 3 precursor [Homo sapiens];NP_001171754.1//pregnancy-specific beta-1-glycoprotein 1 isoform 2 precursor [Homo sapiens]","1//3;2//1"]
[124872,1806,0.36,0.27,-0.415037499278844,0.612608866952069,"*",0.456868,"B4GALNT2","GO:0030173//integral component of Golgi membrane;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0008376//acetylgalactosaminyltransferase activity","GO:0006047//UDP-N-acetylglucosamine metabolic process;GO:0022408//negative regulation of cell-cell adhesion;GO:0018279//protein N-linked glycosylation via asparagine;GO:0030259//lipid glycosylation;GO:0019276//UDP-N-acetylgalactosamine metabolic process","K09655//beta-1,4-N-acetylgalactosaminyltransferase 2 [EC:2.4.1.-]","NP_001152859.1//beta-1,4 N-acetylgalactosaminyltransferase 2 isoform b [Homo sapiens];NP_703147.2//beta-1,4 N-acetylgalactosaminyltransferase 2 isoform a [Homo sapiens];AAM34756.1//beta-4-N-acetylgalactosaminyltransferase [Homo sapiens]","1//3;2//1"]
[222658,5476,5.92,4.44,-0.415037499278844,{"v":4.942017864E-5,"d":"4.94E-05"},"*",{"v":1.082826E-5,"d":"1.08E-05"},"KCTD20","GO:0005737//cytoplasm","NA","GO:0042327//positive regulation of phosphorylation","K10482//BTB/POZ domain-containing protein 10","NP_001273508.1//BTB/POZ domain-containing protein KCTD20 isoform b [Homo sapiens];NP_775833.2//BTB/POZ domain-containing protein KCTD20 isoform a [Homo sapiens];XP_527371.1//PREDICTED: BTB/POZ domain-containing protein KCTD20 isoform X1 [Pan troglodytes]","4;1//3"]
[51193,2999,5.77,4.33,-0.414204293918757,0.0162204903921904,"*",0.0059291,"ZNF639","GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0043621//protein self-association;GO:0044212//transcription regulatory region DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0043922//negative regulation by host of viral transcription;GO:0030307//positive regulation of cell growth;GO:0046718//viral entry into host cell;GO:0043923//positive regulation by host of viral transcription","K09228//KRAB domain-containing zinc finger protein","NP_057415.1//zinc finger protein 639 [Homo sapiens]","1//3;2//1"]
[1491,2140,1.25,0.94,-0.41119543298445,0.448666874895046,"*",0.301068,"CTH","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0004123//cystathionine gamma-lyase activity;GO:0044540//L-cystine L-cysteine-lyase (deaminating);GO:0042802//identical protein binding;GO:0016846//carbon-sulfur lyase activity;GO:0080146//L-cysteine desulfhydrase activity;GO:0005516//calmodulin binding;GO:0030170//pyridoxal phosphate binding;GO:0047982//homocysteine desulfhydrase activity;GO:0003962//cystathionine gamma-synthase activity","GO:0019346//transsulfuration;GO:0051289//protein homotetramerization;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0000098//sulfur amino acid catabolic process;GO:0071266//'de novo' L-methionine biosynthetic process;GO:1904831//positive regulation of aortic smooth muscle cell differentiation;GO:0044524//protein sulfhydration;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:1990830//cellular response to leukemia inhibitory factor;GO:0019343//cysteine biosynthetic process via cystathionine;GO:0006534//cysteine metabolic process;GO:0018272//protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine;GO:0070814//hydrogen sulfide biosynthetic process;GO:0019344//cysteine biosynthetic process;GO:0030968//endoplasmic reticulum unfolded protein response;GO:2001234//negative regulation of apoptotic signaling pathway","K01758//cystathionine gamma-lyase [EC:4.4.1.1]","NP_714964.2//cystathionine gamma-lyase isoform 2 [Homo sapiens];NP_001177392.1//cystathionine gamma-lyase isoform 3 [Homo sapiens];NP_001893.2//cystathionine gamma-lyase isoform 1 [Homo sapiens]","1//3;4;5"]
[10110,1913,9.16,6.89,-0.410843615392653,0.00844121465930018,"*",0.0028694,"SGK2","GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005622//intracellular","GO:0004674//protein serine/threonine kinase activity;GO:0015459//potassium channel regulator activity;GO:0005524//ATP binding;GO:0017080//sodium channel regulator activity;GO:0005246//calcium channel regulator activity;GO:0017081//chloride channel regulator activity","GO:0001558//regulation of cell growth;GO:0034220//ion transmembrane transport;GO:0042127//regulation of cell proliferation;GO:0006468//protein phosphorylation;GO:0032411//positive regulation of transporter activity;GO:0035556//intracellular signal transduction;GO:0006979//response to oxidative stress;GO:0018105//peptidyl-serine phosphorylation;GO:0042981//regulation of apoptotic process","K13303//serum/glucocorticoid-regulated kinase 2 [EC:2.7.11.1]","NP_057360.2//serine/threonine-protein kinase Sgk2 isoform beta [Homo sapiens]","1//3;3//A2MP1;2//1"]
[66036,7421,2.99,2.25,-0.410220482981068,0.00528119370777842,"*",0.0017129,"MTMR9","GO:0005829//cytosol","GO:0030234//enzyme regulator activity;GO:0004438//phosphatidylinositol-3-phosphatase activity;GO:0052629//phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity","GO:0006661//phosphatidylinositol biosynthetic process","K18084//myotubularin-related protein 9","NP_056273.2//myotubularin-related protein 9 [Homo sapiens]","3//A2MP1"]
[6483,4450,12.01,9.04,-0.409841473290446,{"v":7.14270831227258e-06,"d":"7.14E-06"},"*",{"v":1.351722e-06,"d":"1.35E-06"},"ST3GAL2","GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane","GO:0008373//sialyltransferase activity","GO:0006486//protein glycosylation","K03368//beta-galactoside alpha-2,3-sialyltransferase (sialyltransferase 4B) [EC:2.4.99.4]","XP_006974157.1//PREDICTED: CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 [Peromyscus maniculatus bairdii]","3//A2MP1"]
[114804,4851,10.8,8.13,-0.409704054975803,{"v":7.36122237594979e-06,"d":"7.36E-06"},"*",{"v":1.394918e-06,"d":"1.39E-06"},"RNF157","NA","GO:0046872//metal ion binding","NA","K10604//E3 ubiquitin-protein ligase MGRN1 [EC:2.3.2.27]","NP_443148.1//RING finger protein 157 isoform 1 [Homo sapiens];NP_001317430.1//RING finger protein 157 isoform 2 [Homo sapiens]","1//3;2//1"]
[23300,4860,13.95,10.51,-0.408502452754371,{"v":2.97758229971417E-7,"d":"2.98E-07"},"*",{"v":4.56498e-08,"d":"4.56E-08"},"ATMIN","GO:0016604//nuclear body","GO:0070840//dynein complex binding;GO:0046872//metal ion binding;GO:0044212//transcription regulatory region DNA binding;GO:0003676//nucleic acid binding","GO:1902857//positive regulation of non-motile cilium assembly;GO:0006351//transcription, DNA-templated;GO:0044458//motile cilium assembly;GO:0006974//cellular response to DNA damage stimulus;GO:0045893//positive regulation of transcription, DNA-templated","K12581//CCR4-NOT transcription complex subunit 7/8;K11447//histone demethylase [EC:1.14.11.-];K17985//activating molecule in BECN1-regulated autophagy protein 1;K15696//RING finger protein 113B","NP_056066.2//ATM interactor isoform 1 [Homo sapiens];AAH02701.2//ATMIN protein, partial [Homo sapiens]","1//3;2//1"]
[9086,1413,1.26,0.95,-0.407424315168969,0.493296860699682,"*",0.339848,"EIF1AY","NA","GO:0003743//translation initiation factor activity;GO:0043023//ribosomal large subunit binding","NA","K03236//translation initiation factor 1A","XP_011832202.1//PREDICTED: eukaryotic translation initiation factor 1A, Y-chromosomal-like [Mandrillus leucophaeus];OBS60797.1//hypothetical protein A6R68_08078, partial [Neotoma lepida]","1//3;3//A2MP1"]
[387893,2682,27.56,20.78,-0.407380233800079,{"v":2.40372892307692e-08,"d":"2.40E-08"},"*",{"v":3.18862e-09,"d":"3.19E-09"},"KMT5A","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005694//chromosome","GO:0016279//protein-lysine N-methyltransferase activity;GO:0016278//lysine N-methyltransferase activity;GO:0003714//transcription corepressor activity;GO:0002039//p53 binding;GO:0042799//histone methyltransferase activity (H4-K20 specific);GO:0018024//histone-lysine N-methyltransferase activity","GO:1901796//regulation of signal transduction by p53 class mediator;GO:0043516//regulation of DNA damage response, signal transduction by p53 class mediator;GO:0018026//peptidyl-lysine monomethylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0051301//cell division;GO:0006351//transcription, DNA-templated;GO:0007049//cell cycle","K11428//histone-lysine N-methyltransferase SETD8 [EC:2.1.1.43]","NP_065115.3//N-lysine methyltransferase KMT5A isoform 1 [Homo sapiens];NP_001311433.1//N-lysine methyltransferase KMT5A isoform 2 [Homo sapiens];Q9NQR1.3//RecName: Full=N-lysine methyltransferase KMT5A; AltName: Full=H4-K20-HMTase KMT5A; AltName: Full=Histone-lysine N-methyltransferase KMT5A; AltName: Full=Lysine N-methyltransferase 5A; AltName: Full=Lysine-specific methylase 5A; AltName: Full=PR/SET domain-containing protein 07; Short=PR-Set7; Short=PR/SET07; AltName: Full=SET domain-containing protein 8;EAW98406.1//SET domain containing (lysine methyltransferase) 8, isoform CRA_a, partial [Homo sapiens]","1//3;4"]
[64781,4445,10.8,8.15,-0.406159347932391,{"v":2.642123477429e-05,"d":"2.64E-05"},"*",{"v":5.53268e-06,"d":"5.53E-06"},"CERK","GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005886//plasma membrane","GO:0000287//magnesium ion binding;GO:0003951//NAD+ kinase activity;GO:0102773//dihydroceramide kinase activity;GO:0005524//ATP binding;GO:0001729//ceramide kinase activity","GO:0006687//glycosphingolipid metabolic process;GO:0006672//ceramide metabolic process","K04715//ceramide kinase [EC:2.7.1.138]","NP_073603.2//ceramide kinase [Homo sapiens]",5]
[6041,4258,1.06,0.8,-0.405992359675837,0.28630919245283,"*",0.16624,"RNASEL","GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0016363//nuclear matrix","GO:0003723//RNA binding;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0004521//endoribonuclease activity;GO:0046872//metal ion binding;GO:0004672//protein kinase activity;GO:0043021//ribonucleoprotein complex binding;GO:0004540//ribonuclease activity;GO:0019843//rRNA binding","GO:2001275//positive regulation of glucose import in response to insulin stimulus;GO:0006397//mRNA processing;GO:0060337//type I interferon signaling pathway;GO:0006468//protein phosphorylation;GO:0051607//defense response to virus;GO:0006364//rRNA processing;GO:0045444//fat cell differentiation;GO:0045071//negative regulation of viral genome replication;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0060338//regulation of type I interferon-mediated signaling pathway;GO:0043488//regulation of mRNA stability","K01165//ribonuclease L","NP_066956.1//2-5A-dependent ribonuclease [Homo sapiens]","3//A2MP1"]
[441549,1330,0.49,0.37,-0.405256478486259,0.723442971411599,"*",0.609904,"CDNF","GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum","GO:0008083//growth factor activity","GO:0031175//neuron projection development;GO:0071542//dopaminergic neuron differentiation","K13190//RNA-binding protein 15","NP_001025125.2//cerebral dopamine neurotrophic factor precursor [Homo sapiens]","2//1"]
[23524,9379,100.25,75.73,-0.404665402857668,{"v":2.35756166477876e-87,"d":"2.36E-87"},"*",{"v":1.667738e-89,"d":"1.67E-89"},"SRRM2","GO:0005654//nucleoplasm;GO:0016607//nuclear speck;GO:0015030//Cajal body;GO:0071013//catalytic step 2 spliceosome","GO:0003723//RNA binding;GO:0070742//C2H2 zinc finger domain binding;GO:0047485//protein N-terminus binding","GO:0000398//mRNA splicing, via spliceosome","K13172//serine/arginine repetitive matrix protein 2","NP_057417.3//serine/arginine repetitive matrix protein 2 [Homo sapiens]","3//A2MP1"]
[83932,3663,3.98,3.01,-0.403004943783947,0.0313552480731054,"*",0.01245848,"SPRTN","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016607//nuclear speck;GO:0005694//chromosome","GO:0070530//K63-linked polyubiquitin modification-dependent protein binding;GO:0043130//ubiquitin binding;GO:0046872//metal ion binding;GO:0003677//DNA binding","GO:0019985//translesion synthesis;GO:0070987//error-free translesion synthesis;GO:0006281//DNA repair;GO:0009411//response to UV;GO:0031398//positive regulation of protein ubiquitination;GO:0006974//cellular response to DNA damage stimulus","K08049//adenylate cyclase 9 [EC:4.6.1.1]","NP_001010984.1//sprT-like domain-containing protein Spartan isoform b [Homo sapiens];NP_114407.3//sprT-like domain-containing protein Spartan isoform a [Homo sapiens];XP_011542591.1//PREDICTED: sprT-like domain-containing protein Spartan isoform X2 [Homo sapiens]","6;3//A2MP1;2//1"]
[224,3718,64.6,48.87,-0.402585060334613,{"v":2.93903689757576e-22,"d":"2.94E-22"},"*",{"v":1.214326e-23,"d":"1.21E-23"},"ALDH3A2","GO:0016021//integral component of membrane","GO:0004030//aldehyde dehydrogenase [NAD(P)+] activity","GO:0006081//cellular aldehyde metabolic process","K00128//aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]","XP_011932581.1//PREDICTED: fatty aldehyde dehydrogenase isoform X2 [Cercocebus atys];XP_011932579.1//PREDICTED: fatty aldehyde dehydrogenase isoform X1 [Cercocebus atys]","1//3;2//1"]
[7798,8425,6.42,4.86,-0.401616983516522,{"v":1.03749200772947E-5,"d":"1.04E-05"},"*",{"v":2.01666e-06,"d":"2.02E-06"},"LUZP1","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus","NA","GO:0021503//neural fold bending;GO:0060840//artery development;GO:0003281//ventricular septum development","K10352//myosin heavy chain;K12875//apoptotic chromatin condensation inducer in the nucleus","NP_361013.3//leucine zipper protein 1 [Homo sapiens]","1//3;3//A2MP1"]
[9172,5018,0.33,0.25,-0.400537929583729,0.578702636731183,"*",0.421148,"MYOM2","NA","NA","NA","K12567//titin [EC:2.7.11.1]","XP_007959780.1//PREDICTED: myomesin-2 isoform X2 [Chlorocebus sabaeus]","3//A2MP1"]
[23029,2228,21.96,16.64,-0.400222620864106,{"v":3.3528526056338e-05,"d":"3.35E-05"},"*",{"v":7.1532e-06,"d":"7.15E-06"},"RBM34","NA","NA","NA","K14837//nucleolar protein 12;K19195//AT-rich interactive domain-containing protein 4B","XP_018887532.1//PREDICTED: RNA-binding protein 34 isoform X2 [Gorilla gorilla gorilla]","1//3;3//A2MP1"]
[83860,3298,5.79,4.39,-0.399342408453878,0.0140416496220171,"*",0.00504652,"TAF3","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0005669//transcription factor TFIID complex","GO:0046872//metal ion binding;GO:0002039//p53 binding","GO:0006368//transcription elongation from RNA polymerase II promoter;GO:1901796//regulation of signal transduction by p53 class mediator;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0043433//negative regulation of DNA binding transcription factor activity;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0051457//maintenance of protein location in nucleus","K14650//transcription initiation factor TFIID subunit 3","XP_011518043.1//PREDICTED: transcription initiation factor TFIID subunit 3 isoform X1 [Homo sapiens]","3//A2MP1"]
[7803,5093,65.18,49.46,-0.398167112348627,{"v":4.09460732258064e-30,"d":"4.09E-30"},"*",{"v":1.11247e-31,"d":"1.11E-31"},"PTP4A1","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0009898//cytoplasmic side of plasma membrane;GO:0005819//spindle;GO:0005769//early endosome;GO:0005886//plasma membrane","GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0004727//prenylated protein tyrosine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity","GO:0030335//positive regulation of cell migration;GO:0007275//multicellular organism development;GO:0007049//cell cycle","K18041//protein tyrosine phosphatase type IVA [EC:3.1.3.48]","EDL14423.1//protein tyrosine phosphatase 4a1, isoform CRA_b, partial [Mus musculus]",4]
[953,12513,3.53,2.68,-0.397435182813408,1.03744373101952E-4,"*",{"v":2.3952E-5,"d":"2.40E-05"},"ENTPD1","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0102491//dGTP phosphohydrolase activity;GO:0005524//ATP binding;GO:0102485//dATP phosphohydrolase activity;GO:0102490//8-oxo-dGTP phosphohydrolase activity;GO:0102486//dCTP phosphohydrolase activity;GO:0102488//dTTP phosphohydrolase activity;GO:0016787//hydrolase activity;GO:0102487//dUTP phosphohydrolase activity;GO:0017111//nucleoside-triphosphatase activity;GO:0102489//GTP phosphohydrolase activity;GO:0017110//nucleoside-diphosphatase activity","GO:0007155//cell adhesion;GO:0007596//blood coagulation;GO:0034656//nucleobase-containing small molecule catabolic process","K01510//apyrase [EC:3.6.1.5]","NP_001157651.1//ectonucleoside triphosphate diphosphohydrolase 1 isoform 4 [Homo sapiens];XP_011806626.1//PREDICTED: ectonucleoside triphosphate diphosphohydrolase 1 isoform X1 [Colobus angolensis palliatus];NP_001307845.1//ectonucleoside triphosphate diphosphohydrolase 1 isoform 7 [Homo sapiens];NP_001091645.1//ectonucleoside triphosphate diphosphohydrolase 1 isoform 2 [Homo sapiens];XP_002821065.1//PREDICTED: ectonucleoside triphosphate diphosphohydrolase 1 isoform X1 [Pongo abelii];NP_001157650.1//ectonucleoside triphosphate diphosphohydrolase 1 isoform 3 [Homo sapiens]","1//3;5"]
[131544,10767,2.62,1.99,-0.396798380993801,0.00195315478385802,"*",0.000578708,"CRYBG3","GO:0043234//protein complex","GO:0051018//protein kinase A binding;GO:0030246//carbohydrate binding","NA","K13596//activin receptor type-2B [EC:2.7.11.30];K16810//TBCC domain-containing protein 1","NP_705833.3//very large A-kinase anchor protein [Homo sapiens]","3//A2MP1"]
[57563,5275,2.75,2.09,-0.395928676331139,0.0169604149097104,"*",0.00623248,"KLHL8","GO:0005654//nucleoplasm;GO:0031463//Cul3-RING ubiquitin ligase complex","NA","GO:0016567//protein ubiquitination;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process","K10446//kelch-like protein 8","NP_065854.3//kelch-like protein 8 isoform 1 [Homo sapiens];NP_001278936.1//kelch-like protein 8 isoform 3 [Homo sapiens];NP_001278935.1//kelch-like protein 8 isoform 2 [Homo sapiens]","4;1//3"]
[81608,2342,17.48,13.29,-0.395364080224424,0.000156789218205598,"*",{"v":3.75238e-05,"d":"3.75E-05"},"FIP1L1","GO:0005654//nucleoplasm;GO:0005847//mRNA cleavage and polyadenylation specificity factor complex","GO:0003723//RNA binding","GO:0006406//mRNA export from nucleus;GO:0098789//pre-mRNA cleavage required for polyadenylation;GO:0000398//mRNA splicing, via spliceosome;GO:0006369//termination of RNA polymerase II transcription;GO:0031124//mRNA 3'-end processing;GO:0006378//mRNA polyadenylation","K14405//pre-mRNA 3'-end-processing factor FIP1","XP_020017369.1//pre-mRNA 3'-end-processing factor FIP1 [Castor canadensis];NP_001128410.1//pre-mRNA 3'-end-processing factor FIP1 isoform 3 [Homo sapiens];NP_001128409.1//pre-mRNA 3'-end-processing factor FIP1 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[54602,4666,4.26,3.24,-0.394859617341213,0.0128758286877193,"*",0.00459448,"NDFIP2","GO:0043231//intracellular membrane-bounded organelle;GO:0005783//endoplasmic reticulum;GO:0032585//multivesicular body membrane;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005739//mitochondrion","GO:0050699//WW domain binding;GO:0004871//signal transducer activity","GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0031398//positive regulation of protein ubiquitination;GO:0051224//negative regulation of protein transport;GO:0010629//negative regulation of gene expression;GO:0032410//negative regulation of transporter activity","NA","XP_009246988.1//PREDICTED: NEDD4 family-interacting protein 2 isoform X1 [Pongo abelii]","1//3;2//1"]
[84861,2637,7.99,6.08,-0.394124179484391,0.0106627311286844,"*",0.003714,"KLHL22","GO:0005827//polar microtubule;GO:0072686//mitotic spindle;GO:0005829//cytosol;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0031463//Cul3-RING ubiquitin ligase complex","NA","GO:0043687//post-translational protein modification;GO:0000070//mitotic sister chromatid segregation;GO:0006513//protein monoubiquitination;GO:0051301//cell division;GO:0007094//mitotic spindle assembly checkpoint","K10459//kelch-like protein 22","XP_016884509.1//PREDICTED: kelch-like protein 22 isoform X3 [Homo sapiens]","3//A2MP1"]
[25926,2638,36.7,27.94,-0.393448042321112,{"v":2.44121506709265e-09,"d":"2.44E-09"},"*",{"v":2.87004e-10,"d":"2.87E-10"},"NOL11","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0034455//t-UTP complex","GO:0003723//RNA binding","GO:0006351//transcription, DNA-templated;GO:0006364//rRNA processing;GO:0030490//maturation of SSU-rRNA;GO:1901838//positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter","K20478//golgin subfamily B member 1","NP_056277.2//nucleolar protein 11 isoform 1 [Homo sapiens];EAW89036.1//nucleolar protein 11, isoform CRA_d [Homo sapiens]","4;1//3"]
[84517,2017,1.51,1.15,-0.392914688380704,0.423687494143415,"*",0.278524,"ACTRT3","GO:0001673//male germ cell nucleus","NA","NA","K12314//actin, alpha cardiac muscle;K10354//actin, alpha skeletal muscle;K05692//actin beta/gamma 1","XP_011916028.1//PREDICTED: actin-related protein T3 [Cercocebus atys]",4]
[540,6418,1.05,0.8,-0.39231742277876,0.154623303631011,"*",0.0789088,"ATP7B","GO:0016020//membrane;GO:0032588//trans-Golgi network membrane;GO:0005770//late endosome;GO:0005887//integral component of plasma membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005802//trans-Golgi network;GO:0000139//Golgi membrane","GO:0004008//copper-exporting ATPase activity;GO:0005524//ATP binding;GO:0019829//cation-transporting ATPase activity;GO:0000166//nucleotide binding;GO:0005507//copper ion binding;GO:0043682//copper-transporting ATPase activity;GO:0005375//copper ion transmembrane transporter activity","GO:0007595//lactation;GO:0006878//cellular copper ion homeostasis;GO:0051208//sequestering of calcium ion;GO:0034220//ion transmembrane transport;GO:0015680//intracellular copper ion transport;GO:0006882//cellular zinc ion homeostasis;GO:0030001//metal ion transport;GO:0046688//response to copper ion;GO:0006825//copper ion transport;GO:0015677//copper ion import","K17686//Cu+-exporting ATPase [EC:3.6.3.54]","NP_000044.2//copper-transporting ATPase 2 isoform a [Homo sapiens];NP_001317507.1//copper-transporting ATPase 2 isoform d [Homo sapiens];NP_001005918.1//copper-transporting ATPase 2 isoform b [Homo sapiens];NP_001317508.1//copper-transporting ATPase 2 isoform e [Homo sapiens];XP_011794355.1//PREDICTED: copper-transporting ATPase 2 isoform X5 [Colobus angolensis palliatus]","1//3;3//A2MP1;2//1"]
[5563,9369,1.47,1.12,-0.39231742277876,0.0480683629927116,"*",0.0202306,"PRKAA2","GO:0031588//nucleotide-activated protein kinase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0005737//cytoplasm","GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005524//ATP binding;GO:0050405//[acetyl-CoA carboxylase] kinase activity;GO:0035174//histone serine kinase activity;GO:0046872//metal ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0047322//[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity;GO:0004679//AMP-activated protein kinase activity;GO:0003682//chromatin binding;GO:0004672//protein kinase activity","GO:0032007//negative regulation of TOR signaling;GO:0010468//regulation of gene expression;GO:0035690//cellular response to drug;GO:0006355//regulation of transcription, DNA-templated;GO:0006950//response to stress;GO:0035404//histone-serine phosphorylation;GO:0035556//intracellular signal transduction;GO:0042149//cellular response to glucose starvation;GO:0007050//cell cycle arrest;GO:0042593//glucose homeostasis;GO:0014850//response to muscle activity;GO:0045821//positive regulation of glycolytic process;GO:0055089//fatty acid homeostasis;GO:0006914//autophagy;GO:0006633//fatty acid biosynthetic process;GO:0031669//cellular response to nutrient levels;GO:0008610//lipid biosynthetic process;GO:0016241//regulation of macroautophagy;GO:0007165//signal transduction;GO:0006468//protein phosphorylation;GO:0006351//transcription, DNA-templated;GO:0006695//cholesterol biosynthetic process;GO:0043066//negative regulation of apoptotic process;GO:0048511//rhythmic process;GO:0010508//positive regulation of autophagy;GO:1901796//regulation of signal transduction by p53 class mediator;GO:0042752//regulation of circadian rhythm;GO:0042304//regulation of fatty acid biosynthetic process;GO:0016239//positive regulation of macroautophagy;GO:0071380//cellular response to prostaglandin E stimulus;GO:0016055//Wnt signaling pathway;GO:2000505//regulation of energy homeostasis;GO:0006853//carnitine shuttle;GO:0016236//macroautophagy","K07198//5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]","NP_006243.2//5'-AMP-activated protein kinase catalytic subunit alpha-2 [Homo sapiens]","3//A2MP1"]
[84899,3924,2.9,2.21,-0.392006530623503,0.101350477602355,"*",0.0474204,"TMTC4","GO:0016021//integral component of membrane","NA","NA","K09667//protein O-GlcNAc transferase [EC:2.4.1.255]","NP_001273382.1//transmembrane and TPR repeat-containing protein 4 isoform 3 [Homo sapiens];NP_001337505.1//transmembrane and TPR repeat-containing protein 4 isoform 6 [Homo sapiens];NP_001337500.1//transmembrane and TPR repeat-containing protein 4 isoform 4 [Homo sapiens];XP_007958982.1//PREDICTED: transmembrane and TPR repeat-containing protein 4 isoform X1 [Chlorocebus sabaeus];NP_116202.2//transmembrane and TPR repeat-containing protein 4 isoform 1 [Homo sapiens]","1//3;4;3//A2MP1;2//1"]
[9262,5324,3.79,2.89,-0.391128355670413,0.0120259379100248,"*",0.00425056,"STK17B","GO:0005634//nucleus;GO:0015629//actin cytoskeleton;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005886//plasma membrane","GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity","GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction;GO:0046777//protein autophosphorylation;GO:2000271//positive regulation of fibroblast apoptotic process;GO:0006915//apoptotic process","K08804//serine/threonine kinase 17 [EC:2.7.11.1]","NP_004217.1//serine/threonine-protein kinase 17B [Homo sapiens]","3//A2MP1"]
[84804,5313,3.33,2.54,-0.390693680299096,0.0241921397267404,"*",0.00931096,"MFSD9","GO:0016021//integral component of membrane","GO:0005215//transporter activity","GO:0055085//transmembrane transport","K08214//MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 18","NP_116107.3//major facilitator superfamily domain-containing protein 9 isoform 1 [Homo sapiens];XP_011812004.1//PREDICTED: major facilitator superfamily domain-containing protein 9 isoform X1 [Colobus angolensis palliatus]","4;1//3"]
[127428,6031,1.9,1.45,-0.389946518316013,0.0880612477099237,"*",0.0404418,"TCEANC2","GO:0005634//nucleus","NA","GO:0006351//transcription, DNA-templated","K01064//wingless-type MMTV integration site family, member 9","XP_012362198.1//PREDICTED: transcription elongation factor A N-terminal and central domain-containing protein 2 isoform X1 [Nomascus leucogenys]","2//1"]
[257407,3595,3.38,2.58,-0.38965218085893,0.0676172804895403,"*",0.029745,"C2orf72","NA","NA","NA","K19475//WAS/WASL-interacting protein","NP_001138466.1//uncharacterized protein C2orf72 [Homo sapiens]","1//3"]
[177,1439,2.79,2.13,-0.389411691603349,0.333971328552126,"*",0.201148,"AGER","GO:0098794//postsynapse;GO:0016324//apical plasma membrane;GO:0030054//cell junction;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0001650//fibrillar center;GO:0005886//plasma membrane","GO:0038023//signaling receptor activity;GO:0001540//amyloid-beta binding;GO:0050785//advanced glycation end-product receptor activity;GO:1904599//advanced glycation end-product binding;GO:0004872//receptor activity;GO:0042802//identical protein binding;GO:0044548//S100 protein binding;GO:0005044//scavenger receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0008201//heparin binding","GO:0046330//positive regulation of JNK cascade;GO:0050930//induction of positive chemotaxis;GO:1904604//negative regulation of advanced glycation end-product receptor activity;GO:0007166//cell surface receptor signaling pathway;GO:0014002//astrocyte development;GO:1904645//response to amyloid-beta;GO:0051101//regulation of DNA binding;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:1900453//negative regulation of long term synaptic depression;GO:0045087//innate immune response;GO:0042104//positive regulation of activated T cell proliferation;GO:0009611//response to wounding;GO:0001914//regulation of T cell mediated cytotoxicity;GO:0001666//response to hypoxia;GO:2000514//regulation of CD4-positive, alpha-beta T cell activation;GO:1904597//negative regulation of connective tissue replacement involved in inflammatory response wound healing;GO:0048167//regulation of synaptic plasticity;GO:0010255//glucose mediated signaling pathway;GO:1900744//regulation of p38MAPK cascade;GO:0032693//negative regulation of interleukin-10 production;GO:0072657//protein localization to membrane;GO:1901222//regulation of NIK/NF-kappaB signaling;GO:0071639//positive regulation of monocyte chemotactic protein-1 production;GO:0032735//positive regulation of interleukin-12 production;GO:0090647//modulation of age-related behavioral decline;GO:1900272//negative regulation of long-term synaptic potentiation;GO:0031175//neuron projection development;GO:0001934//positive regulation of protein phosphorylation;GO:0007611//learning or memory;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:1903980//positive regulation of microglial cell activation;GO:0043507//positive regulation of JUN kinase activity;GO:0061890//positive regulation of astrocyte activation;GO:0006954//inflammatory response;GO:0042346//positive regulation of NF-kappaB import into nucleus;GO:1900745//positive regulation of p38MAPK cascade;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:2001200//positive regulation of dendritic cell differentiation","K19722//receptor for advanced glycosylation end products","XP_008953385.1//PREDICTED: advanced glycosylation end product-specific receptor isoform X4 [Pan paniscus];XP_003829814.1//PREDICTED: advanced glycosylation end product-specific receptor isoform X1 [Pan paniscus];XP_004043792.1//PREDICTED: advanced glycosylation end product-specific receptor isoform X3 [Gorilla gorilla gorilla];BAG60385.1//unnamed protein product [Homo sapiens];XP_009449255.1//PREDICTED: advanced glycosylation end product-specific receptor isoform X8 [Pan troglodytes];XP_008953386.1//PREDICTED: advanced glycosylation end product-specific receptor isoform X6 [Pan paniscus]","4;1//3;2//1"]
[51776,5604,19.28,14.73,-0.388347621194112,{"v":1.46080045824095e-12,"d":"1.46E-12"},"*",{"v":1.2373e-13,"d":"1.24E-13"},"MAP3K20","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0000287//magnesium ion binding;GO:0003723//RNA binding;GO:0004709//MAP kinase kinase kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding","GO:0006950//response to stress;GO:0035556//intracellular signal transduction;GO:0007050//cell cycle arrest;GO:0042733//embryonic digit morphogenesis;GO:0043065//positive regulation of apoptotic process;GO:0008283//cell proliferation;GO:0000186//activation of MAPKK activity;GO:0030154//cell differentiation;GO:0000077//DNA damage checkpoint;GO:0006468//protein phosphorylation;GO:0008219//cell death;GO:0007257//activation of JUN kinase activity;GO:0000075//cell cycle checkpoint;GO:0060173//limb development;GO:0009314//response to radiation;GO:0007010//cytoskeleton organization","K04424//sterile alpha motif and leucine zipper containing kinase AZK [EC:2.7.11.25]","BAD92211.1//Plaucible mixed-lineage kinase protein variant, partial [Homo sapiens];XP_011801357.1//PREDICTED: mitogen-activated protein kinase kinase kinase MLT isoform X2 [Colobus angolensis palliatus]","2//1"]
[3915,7889,25.11,19.2,-0.387155717662981,{"v":1.70190087741936E-17,"d":"1.70E-17"},"*",{"v":9.9084e-19,"d":"9.91E-19"},"LAMC1","GO:0043260//laminin-11 complex;GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0005606//laminin-1 complex;GO:0043259//laminin-10 complex;GO:0005576//extracellular region;GO:0005604//basement membrane","GO:0005201//extracellular matrix structural constituent","GO:0043687//post-translational protein modification;GO:0007492//endoderm development;GO:0016477//cell migration;GO:0034446//substrate adhesion-dependent cell spreading;GO:0031581//hemidesmosome assembly;GO:0044267//cellular protein metabolic process;GO:0022617//extracellular matrix disassembly;GO:0007155//cell adhesion;GO:0030198//extracellular matrix organization;GO:0006461//protein complex assembly;GO:0050679//positive regulation of epithelial cell proliferation","K05635//laminin, gamma 1","NP_002284.3//laminin subunit gamma-1 precursor [Homo sapiens]","3//A2MP1"]
[113791,2399,0.17,0.13,-0.387023123109247,0.833573204995515,"*",0.75629,"PIK3IP1","GO:0070062//extracellular exosome;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0016301//kinase activity;GO:0036313//phosphatidylinositol 3-kinase catalytic subunit binding","GO:0014067//negative regulation of phosphatidylinositol 3-kinase signaling;GO:0043553//negative regulation of phosphatidylinositol 3-kinase activity","K01343//tissue plasminogen activator [EC:3.4.21.68];K13912//deleted in malignant brain tumors 1 protein","NP_001129383.1//phosphoinositide-3-kinase-interacting protein 1 isoform 2 precursor [Homo sapiens];NP_443112.2//phosphoinositide-3-kinase-interacting protein 1 isoform 1 precursor [Homo sapiens]","1//3;4"]
[272,4168,2.34,1.79,-0.386548942319148,0.0473992448398152,"*",0.01991338,"AMPD3","NA","GO:0046872//metal ion binding;GO:0003876//AMP deaminase activity","GO:0046034//ATP metabolic process;GO:0034101//erythrocyte homeostasis;GO:0032264//IMP salvage;GO:0046031//ADP metabolic process;GO:0046033//AMP metabolic process;GO:0046039//GTP metabolic process;GO:0097009//energy homeostasis","K01490//AMP deaminase [EC:3.5.4.6]","XP_017200847.1//PREDICTED: LOW QUALITY PROTEIN: AMP deaminase 3 [Oryctolagus cuniculus];XP_011994561.1//PREDICTED: AMP deaminase 3 isoform X5 [Ovis aries musimon]","1//3;2//1"]
[7637,7056,1.79,1.37,-0.38578369430373,0.0651788505287225,"*",0.028554,"ZNF84","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0003676//nucleic acid binding","GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0001822//kidney development;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0048745//smooth muscle tissue development;GO:0014909//smooth muscle cell migration;GO:0035264//multicellular organism growth;GO:0006807//nitrogen compound metabolic process;GO:0009791//post-embryonic development;GO:0060325//face morphogenesis;GO:0060021//palate development;GO:0001570//vasculogenesis;GO:0030097//hemopoiesis;GO:0048705//skeletal system morphogenesis","K09228//KRAB domain-containing zinc finger protein","NP_001127531.1//zinc finger protein 84 [Pongo abelii]","1//3;2//1;5"]
[4199,3519,30.56,23.4,-0.385136013564982,{"v":1.03272750736842e-09,"d":"1.03E-09"},"*",{"v":1.166942e-10,"d":"1.17E-10"},"ME1","NA","NA","NA","K00029//malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40]","XP_017738116.1//PREDICTED: LOW QUALITY PROTEIN: NADP-dependent malic enzyme [Rhinopithecus bieti]",5]
[146909,4257,43.32,33.19,-0.384284613530027,{"v":9.03474298767773e-16,"d":"9.03E-16"},"*",{"v":5.96698e-17,"d":"5.97E-17"},"KIF18B","GO:0005634//nucleus;GO:0035371//microtubule plus-end;GO:0005737//cytoplasm;GO:1990752//microtubule end;GO:0000235//astral microtubule;GO:0005829//cytosol;GO:0016604//nuclear body;GO:0005871//kinesin complex","GO:0005524//ATP binding;GO:0003774//motor activity;GO:0003777//microtubule motor activity;GO:0019894//kinesin binding;GO:0008017//microtubule binding;GO:0016887//ATPase activity","GO:0000070//mitotic sister chromatid segregation;GO:0000278//mitotic cell cycle;GO:0007018//microtubule-based movement;GO:0051302//regulation of cell division;GO:0051301//cell division;GO:0007019//microtubule depolymerization","K10401//kinesin family member 18/19","XP_011522690.1//PREDICTED: kinesin-like protein KIF18B isoform X4 [Homo sapiens];ADE43428.1//KIF18B [Homo sapiens]","1//3"]
[285349,5948,0.9,0.69,-0.383328639551506,0.297463133083592,"*",0.1739826,"ZNF660","NA","NA","NA","K09229//KRAB and SCAN domains-containing zinc finger protein","XP_012789520.1//PREDICTED: zinc finger protein 197 isoform X2 [Sorex araneus]","3//A2MP1"]
[4238,4732,6.05,4.64,-0.382810337034385,1.21568290605061E-3,"*",0.000345892,"MFAP3","GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K17985//activating molecule in BECN1-regulated autophagy protein 1;K04006//decay accelerating factor","XP_018883219.1//PREDICTED: microfibril-associated glycoprotein 3 isoform X1 [Gorilla gorilla gorilla]","1//3;4"]
[1399,5336,10.36,7.95,-0.381997237514836,{"v":2.27051732484076e-05,"d":"2.27E-05"},"*",{"v":4.6863e-06,"d":"4.69E-06"},"CRKL","GO:0070062//extracellular exosome;GO:0005768//endosome;GO:0005829//cytosol","GO:0005070//SH3/SH2 adaptor activity;GO:0003723//RNA binding;GO:0001784//phosphotyrosine residue binding;GO:0042802//identical protein binding;GO:0004871//signal transducer activity;GO:0045296//cadherin binding","GO:0009952//anterior/posterior pattern specification;GO:0060017//parathyroid gland development;GO:0007507//heart development;GO:0048538//thymus development;GO:0035556//intracellular signal transduction;GO:0001568//blood vessel development;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:0007254//JNK cascade;GO:0009887//animal organ morphogenesis;GO:0007265//Ras protein signal transduction;GO:0008284//positive regulation of cell proliferation;GO:0000186//activation of MAPKK activity","K04438//proto-oncogene C-crk","XP_006140254.2//PREDICTED: crk-like protein [Tupaia chinensis]","3//A2MP1"]
[22877,8439,11.14,8.55,-0.381752907566772,{"v":1.56674034949592E-8,"d":"1.57E-08"},"*",{"v":2.04302e-09,"d":"2.04E-09"},"MLXIP","GO:0005634//nucleus;GO:0005741//mitochondrial outer membrane","GO:0000989//transcription factor activity, transcription factor binding;GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0046983//protein dimerization activity","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:1900402//regulation of carbohydrate metabolic process by regulation of transcription from RNA polymerase II promoter;GO:0045944//positive regulation of transcription from RNA polymerase II promoter","K09113//MAX-like protein X","NP_055753.3//MLX-interacting protein [Homo sapiens]",5]
[319,1720,0.56,0.43,-0.381090167355506,0.765507690140845,"*",0.666884,"APOF","GO:0034364//high-density lipoprotein particle;GO:0034362//low-density lipoprotein particle;GO:0005576//extracellular region","GO:0005319//lipid transporter activity;GO:0015485//cholesterol binding;GO:0005102//receptor binding","GO:0008203//cholesterol metabolic process;GO:0006869//lipid transport;GO:0006629//lipid metabolic process","K01368//cathepsin S [EC:3.4.22.27];K17985//activating molecule in BECN1-regulated autophagy protein 1;K00731//glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase [EC:2.4.1.122];K03155//timeless","XP_009246176.1//PREDICTED: apolipoprotein F isoform X1 [Pongo abelii]","2//1"]
[100131211,3637,1.9,1.46,-0.380031049450931,0.205642136345639,"*",0.1105452,"NEMP2","GO:0005635//nuclear envelope;GO:0016021//integral component of membrane","NA","NA","NA","BAH12468.1//unnamed protein product [Homo sapiens]","1//3"]
[8799,1642,15.73,12.09,-0.379704426166563,6.10735925461114E-3,"*",0.00201068,"PEX11B","GO:0016020//membrane;GO:0005779//integral component of peroxisomal membrane;GO:0070062//extracellular exosome;GO:0043234//protein complex;GO:0005777//peroxisome;GO:0005778//peroxisomal membrane","GO:0042803//protein homodimerization activity","GO:0007031//peroxisome organization;GO:0007165//signal transduction;GO:0044375//regulation of peroxisome size;GO:0051260//protein homooligomerization;GO:0016559//peroxisome fission","K13352//peroxin-11B","NP_001171724.1//peroxisomal membrane protein 11B isoform 2 [Homo sapiens];NP_003837.1//peroxisomal membrane protein 11B isoform 1 [Homo sapiens]","1//3;2//1"]
[84168,4836,39.95,30.72,-0.379017287094183,{"v":8.38482866666667e-31,"d":"8.38E-31"},"*",{"v":2.2046e-32,"d":"2.20E-32"},"ANTXR1","GO:0070062//extracellular exosome;GO:0010008//endosome membrane;GO:0009897//external side of plasma membrane;GO:0031258//lamellipodium membrane;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0031527//filopodium membrane;GO:0005886//plasma membrane","GO:0051015//actin filament binding;GO:0046872//metal ion binding;GO:0005518//collagen binding;GO:0004872//receptor activity;GO:0004888//transmembrane signaling receptor activity","GO:1901202//negative regulation of extracellular matrix assembly;GO:1905050//positive regulation of metallopeptidase activity;GO:0031532//actin cytoskeleton reorganization;GO:0034446//substrate adhesion-dependent cell spreading;GO:0022414//reproductive process;GO:0001568//blood vessel development","K20909//anthrax toxin receptor","XP_011800651.1//PREDICTED: anthrax toxin receptor 1 isoform X2 [Colobus angolensis palliatus];NP_060623.2//anthrax toxin receptor 1 isoform 3 precursor [Homo sapiens];NP_115584.1//anthrax toxin receptor 1 isoform 1 precursor [Homo sapiens]","3//A2MP1;2//1"]
[254251,5587,3.38,2.6,-0.37851162325373,0.0266961069222097,"*",0.01037662,"LCORL","GO:0005634//nucleus","GO:0003677//DNA binding","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter","K20015//ecdysone-induced protein 93F, isoform B;K06678//condensin complex subunit 3","NP_710153.2//ligand-dependent nuclear receptor corepressor-like protein isoform 2 [Homo sapiens];NP_001159611.1//ligand-dependent nuclear receptor corepressor-like protein isoform 1 [Homo sapiens]","8;2//1"]
[64800,4933,0.13,0.1,-0.37851162325373,0.723335547999109,"*",0.609904,"EFCAB6","GO:0005654//nucleoplasm","GO:0005509//calcium ion binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K02183//calmodulin","XP_016884400.1//PREDICTED: EF-hand calcium-binding domain-containing protein 6 isoform X4 [Homo sapiens]","3//A2MP1;2//1"]
[6519,2353,2.52,1.94,-0.377367081312789,0.250428690261177,"*",0.1416598,"SLC3A1","GO:0005774//vacuolar membrane;GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005887//integral component of plasma membrane;GO:0031526//brush border membrane;GO:0005743//mitochondrial inner membrane;GO:0005886//plasma membrane","GO:0015174//basic amino acid transmembrane transporter activity;GO:0046982//protein heterodimerization activity;GO:0003824//catalytic activity;GO:0015184//L-cystine transmembrane transporter activity;GO:0015171//amino acid transmembrane transporter activity","GO:0015802//basic amino acid transport;GO:0006865//amino acid transport;GO:0006520//cellular amino acid metabolic process;GO:0005975//carbohydrate metabolic process;GO:0015811//L-cystine transport","K14210//solute carrier family 3 (neutral and basic amino acid transporter), member 1","NP_000332.2//neutral and basic amino acid transport protein rBAT [Homo sapiens]","3//A2MP1"]
[29090,1562,16.25,12.52,-0.376205155870561,0.00727397328838951,"*",0.00243164,"TIMM21","GO:0005744//mitochondrial inner membrane presequence translocase complex;GO:0016021//integral component of membrane","NA","GO:0033617//mitochondrial respiratory chain complex IV assembly;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0030150//protein import into mitochondrial matrix","K17796//mitochondrial import inner membrane translocase subunit TIM21","NP_054896.2//mitochondrial import inner membrane translocase subunit Tim21 precursor [Homo sapiens]","2//1"]
[6294,3119,20.39,15.71,-0.3761785947224,{"v":7.47586887726048e-07,"d":"7.48E-07"},"*",{"v":1.216338E-7,"d":"1.22E-07"},"SAFB","GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0003723//RNA binding;GO:0003682//chromatin binding;GO:0043565//sequence-specific DNA binding;GO:0003690//double-stranded DNA binding;GO:0001047//core promoter binding","GO:0030520//intracellular estrogen receptor signaling pathway;GO:0042445//hormone metabolic process;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0050684//regulation of mRNA processing;GO:0006325//chromatin organization;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0040007//growth","K00753//glycoprotein 3-alpha-L-fucosyltransferase [EC:2.4.1.214];K12875//apoptotic chromatin condensation inducer in the nucleus;K18626//trichohyalin;K20780//mediator of DNA damage checkpoint protein 1","NP_002958.2//scaffold attachment factor B1 isoform 3 [Homo sapiens];NP_001188268.1//scaffold attachment factor B1 isoform 2 [Homo sapiens];NP_001188269.1//scaffold attachment factor B1 isoform 4 [Homo sapiens];NP_001188267.1//scaffold attachment factor B1 isoform 1 [Homo sapiens];NP_001307501.1//scaffold attachment factor B1 isoform 6 [Homo sapiens];NP_001307500.1//scaffold attachment factor B1 isoform 5 [Homo sapiens]","1//3;3//A2MP1"]
[54716,5344,0.96,0.74,-0.375509135092206,0.244958318711827,"*",0.13809,"SLC6A20","GO:0005887//integral component of plasma membrane;GO:0016324//apical plasma membrane;GO:0005886//plasma membrane","GO:0005328//neurotransmitter:sodium symporter activity;GO:0015171//amino acid transmembrane transporter activity","GO:0006865//amino acid transport;GO:0015816//glycine transport;GO:0015824//proline transport","K05048//solute carrier family 6 (neurotransmitter transporter, amino acid/orphan) member 15/16/17/18/20","AAL75944.1//neurotransmitter transporter RB21A [Homo sapiens]","3//A2MP1"]
[29945,2701,4.9,3.78,-0.374395514781498,0.0639092716229767,"*",0.0279298,"ANAPC4","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005680//anaphase-promoting complex","GO:0019903//protein phosphatase binding;GO:0004842//ubiquitin-protein transferase activity","GO:0070979//protein K11-linked ubiquitination;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0051301//cell division;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0030071//regulation of mitotic metaphase/anaphase transition;GO:0007049//cell cycle","K03351//anaphase-promoting complex subunit 4","NP_001273685.1//anaphase-promoting complex subunit 4 isoform 1 [Homo sapiens];NP_001125674.1//anaphase-promoting complex subunit 4 [Pongo abelii]","1//3;2//1"]
[8826,7219,29.93,23.1,-0.373699427194681,{"v":8.69112545695364e-18,"d":"8.69E-18"},"*",{"v":4.92936e-19,"d":"4.93E-19"},"IQGAP1","GO:0031252//cell leading edge;GO:0005874//microtubule;GO:0036057//slit diaphragm;GO:0005737//cytoplasm;GO:0030496//midbody;GO:0030426//growth cone;GO:0005911//cell-cell junction;GO:0005829//cytosol;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0015629//actin cytoskeleton;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0016328//lateral plasma membrane;GO:0005886//plasma membrane;GO:0030424//axon;GO:0070062//extracellular exosome;GO:0030667//secretory granule membrane;GO:0005634//nucleus;GO:0005925//focal adhesion;GO:0015630//microtubule cytoskeleton;GO:0043005//neuron projection;GO:0001726//ruffle;GO:0005884//actin filament;GO:0045121//membrane raft;GO:0030529//intracellular ribonucleoprotein complex;GO:0043234//protein complex","GO:0048365//Rac GTPase binding;GO:0043539//protein serine/threonine kinase activator activity;GO:0019903//protein phosphatase binding;GO:0019901//protein kinase binding;GO:0045296//cadherin binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0044548//S100 protein binding;GO:0019904//protein domain specific binding;GO:0051019//mitogen-activated protein kinase binding;GO:0005509//calcium ion binding;GO:0005095//GTPase inhibitor activity;GO:0005516//calmodulin binding;GO:0005096//GTPase activator activity;GO:0032403//protein complex binding","GO:1900086//positive regulation of peptidyl-tyrosine autophosphorylation;GO:0035305//negative regulation of dephosphorylation;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:1903829//positive regulation of cellular protein localization;GO:0071277//cellular response to calcium ion;GO:1990138//neuron projection extension;GO:1990776//response to angiotensin;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0045860//positive regulation of protein kinase activity;GO:0043312//neutrophil degranulation;GO:0036120//cellular response to platelet-derived growth factor stimulus;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:1904754//positive regulation of vascular associated smooth muscle cell migration;GO:1900006//positive regulation of dendrite development;GO:0007165//signal transduction;GO:0051894//positive regulation of focal adhesion assembly;GO:0043406//positive regulation of MAP kinase activity;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0043087//regulation of GTPase activity;GO:0001817//regulation of cytokine production;GO:0072015//glomerular visceral epithelial cell development","K16848//Ras GTPase-activating-like protein IQGAP1","XP_003901440.1//ras GTPase-activating-like protein IQGAP1 isoform X1 [Papio anubis]","3//A2MP1"]
[5256,5325,7.69,5.94,-0.372520667161061,0.00042290760057943,"*",1.096584E-4,"PHKA2","NA","GO:0016301//kinase activity;GO:0005516//calmodulin binding","GO:0005977//glycogen metabolic process","K07190//phosphorylase kinase alpha/beta subunit","XP_008063658.1//phosphorylase b kinase regulatory subunit alpha, liver isoform isoform X1 [Carlito syrichta]","2//1"]
[5198,5400,22.62,17.48,-0.371893744489222,{"v":2.54592905439331e-10,"d":"2.55E-10"},"*",{"v":2.66642e-11,"d":"2.67E-11"},"PFAS","NA","NA","NA","K01952//phosphoribosylformylglycinamidine synthase [EC:6.3.5.3]","XP_018869183.1//PREDICTED: phosphoribosylformylglycinamidine synthase isoform X1 [Gorilla gorilla gorilla]","2//1"]
[84890,3739,12.84,9.93,-0.370779579593929,0.000137833885231176,"*",{"v":3.26594e-05,"d":"3.27E-05"},"ADO","GO:0005829//cytosol;GO:0005739//mitochondrion","GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0046872//metal ion binding;GO:0047800//cysteamine dioxygenase activity","GO:0000098//sulfur amino acid catabolic process;GO:0055114//oxidation-reduction process","K10712//cysteamine dioxygenase [EC:1.13.11.19]","NP_116193.2//2-aminoethanethiol dioxygenase [Homo sapiens]",5]
[1277,5927,7.38,5.71,-0.370130070697553,0.000298443128340383,"*",{"v":7.50872e-05,"d":"7.51E-05"},"COL1A1","GO:0031012//extracellular matrix;GO:0005788//endoplasmic reticulum lumen;GO:0005584//collagen type I trimer;GO:0030141//secretory granule;GO:0005615//extracellular space;GO:0005794//Golgi apparatus;GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0002020//protease binding;GO:0048407//platelet-derived growth factor binding;GO:0046872//metal ion binding;GO:0005201//extracellular matrix structural constituent;GO:0042802//identical protein binding","GO:0043589//skin morphogenesis;GO:0001649//osteoblast differentiation;GO:0030335//positive regulation of cell migration;GO:0071260//cellular response to mechanical stimulus;GO:0007596//blood coagulation;GO:0030199//collagen fibril organization;GO:0007601//visual perception;GO:0071356//cellular response to tumor necrosis factor;GO:0001568//blood vessel development;GO:0071306//cellular response to vitamin E;GO:0032964//collagen biosynthetic process;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0032355//response to estradiol;GO:0015031//protein transport;GO:0042493//response to drug;GO:0044691//tooth eruption;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0031960//response to corticosteroid;GO:0071300//cellular response to retinoic acid;GO:0030198//extracellular matrix organization;GO:0055093//response to hyperoxia;GO:0048706//embryonic skeletal system development;GO:0030574//collagen catabolic process;GO:0030168//platelet activation;GO:0045893//positive regulation of transcription, DNA-templated;GO:1902618//cellular response to fluoride;GO:0060351//cartilage development involved in endochondral bone morphogenesis;GO:0060346//bone trabecula formation;GO:0070208//protein heterotrimerization;GO:0050776//regulation of immune response;GO:0034505//tooth mineralization;GO:0001958//endochondral ossification;GO:0050900//leukocyte migration;GO:0043434//response to peptide hormone;GO:0051591//response to cAMP;GO:0001957//intramembranous ossification;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0042542//response to hydrogen peroxide;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0071230//cellular response to amino acid stimulus;GO:0038063//collagen-activated tyrosine kinase receptor signaling pathway;GO:0007605//sensory perception of sound;GO:0010812//negative regulation of cell-substrate adhesion;GO:0060325//face morphogenesis;GO:0034504//protein localization to nucleus;GO:0001501//skeletal system development","K06236//collagen, type I, alpha","BAD92834.1//Collagen alpha 1 chain precursor variant, partial [Homo sapiens]","3//A2MP1"]
[10939,3223,19.32,14.95,-0.369949609750306,{"v":1.21510353076187E-5,"d":"1.22E-05"},"*",{"v":2.38624E-6,"d":"2.39E-06"},"AFG3L2","GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0005745//m-AAA complex","GO:0008237//metallopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0005524//ATP binding;GO:0051082//unfolded protein binding;GO:0008270//zinc ion binding","GO:0007528//neuromuscular junction development;GO:0042552//myelination;GO:0006851//mitochondrial calcium ion transmembrane transport;GO:0016540//protein autoprocessing;GO:0042407//cristae formation;GO:0036444//mitochondrial calcium uptake;GO:0040014//regulation of multicellular organism growth;GO:0048747//muscle fiber development;GO:0007409//axonogenesis;GO:0021675//nerve development;GO:0051560//mitochondrial calcium ion homeostasis;GO:0008053//mitochondrial fusion;GO:0006508//proteolysis;GO:0016485//protein processing;GO:0060013//righting reflex;GO:0034982//mitochondrial protein processing","K08956//AFG3 family protein [EC:3.4.24.-]","NP_006787.2//AFG3-like protein 2 [Homo sapiens]","2//1"]
[57473,5938,12.14,9.4,-0.369035759690682,{"v":2.11614790954774e-06,"d":"2.12E-06"},"*",{"v":3.69074e-07,"d":"3.69E-07"},"ZNF512B","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K11728//nucleosome-remodeling factor subunit BPTF;K00876//uridine kinase [EC:2.7.1.48]","XP_005260283.1//PREDICTED: zinc finger protein 512B isoform X1 [Homo sapiens]","2//1"]
[55331,7338,11.58,8.97,-0.368455363069975,{"v":1.54446109137272e-07,"d":"1.54E-07"},"*",{"v":2.27502e-08,"d":"2.28E-08"},"ACER3","GO:0030173//integral component of Golgi membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0070774//phytoceramidase activity","GO:0046512//sphingosine biosynthetic process;GO:0030148//sphingolipid biosynthetic process;GO:0071602//phytosphingosine biosynthetic process;GO:0008284//positive regulation of cell proliferation;GO:0006672//ceramide metabolic process","K04711//dihydroceramidase [EC:3.5.1.-]","NP_001287882.1//alkaline ceramidase 3 isoform b [Homo sapiens];NP_060837.3//alkaline ceramidase 3 isoform a [Homo sapiens]","6;1//3"]
[64172,2047,4.44,3.44,-0.368151111648008,0.154904743396226,"*",0.0791494,"OSGEPL1","GO:0000408//EKC/KEOPS complex;GO:0005739//mitochondrion","GO:0046872//metal ion binding;GO:0004222//metalloendopeptidase activity;GO:0061711//N(6)-L-threonylcarbamoyladenine synthase","GO:0002949//tRNA threonylcarbamoyladenosine modification","K01409//N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]","NP_001341276.1//probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial isoform 2 [Homo sapiens]","1//3;2//1"]
[11231,6500,7.07,5.48,-0.367534321848872,0.000210975216666667,"*",{"v":5.16674e-05,"d":"5.17E-05"},"SEC63","GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005622//intracellular;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0003723//RNA binding;GO:0004872//receptor activity;GO:0008565//protein transporter activity","GO:0010259//multicellular organism aging;GO:0006612//protein targeting to membrane;GO:0001889//liver development;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006807//nitrogen compound metabolic process;GO:0036498//IRE1-mediated unfolded protein response;GO:0072001//renal system development;GO:0006620//posttranslational protein targeting to endoplasmic reticulum membrane;GO:0031204//posttranslational protein targeting to membrane, translocation","K09540//translocation protein SEC63","NP_009145.1//translocation protein SEC63 homolog [Homo sapiens]",4]
[5318,4439,0.98,0.76,-0.366782330671623,0.365874052173913,"*",0.226524,"PKP2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0001533//cornified envelope;GO:0030054//cell junction;GO:0005882//intermediate filament;GO:0005912//adherens junction;GO:0005911//cell-cell junction;GO:0016021//integral component of membrane;GO:0014704//intercalated disc;GO:0005886//plasma membrane;GO:0030057//desmosome","GO:0005080//protein kinase C binding;GO:0032947//protein complex scaffold activity;GO:0044325//ion channel binding;GO:0086083//cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication;GO:0017080//sodium channel regulator activity;GO:0045294//alpha-catenin binding;GO:0019215//intermediate filament binding;GO:0045296//cadherin binding","GO:0098911//regulation of ventricular cardiac muscle cell action potential;GO:2000810//regulation of bicellular tight junction assembly;GO:0031424//keratinization;GO:0070268//cornification;GO:0098609//cell-cell adhesion;GO:0016264//gap junction assembly;GO:0002159//desmosome assembly;GO:0086064//cell communication by electrical coupling involved in cardiac conduction;GO:0008285//negative regulation of cell proliferation;GO:0086019//cell-cell signaling involved in cardiac conduction;GO:0086005//ventricular cardiac muscle cell action potential;GO:0045110//intermediate filament bundle assembly;GO:0086073//bundle of His cell-Purkinje myocyte adhesion involved in cell communication;GO:0072659//protein localization to plasma membrane;GO:0086001//cardiac muscle cell action potential;GO:0007507//heart development;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0086091//regulation of heart rate by cardiac conduction;GO:0030336//negative regulation of cell migration;GO:0010765//positive regulation of sodium ion transport;GO:0086002//cardiac muscle cell action potential involved in contraction;GO:0048496//maintenance of animal organ identity;GO:0034334//adherens junction maintenance;GO:0055088//lipid homeostasis","K12642//plakophilin 2","NP_001005242.2//plakophilin-2 isoform 2a [Homo sapiens];NP_004563.2//plakophilin-2 isoform 2b [Homo sapiens]","3//A2MP1;2//1"]
[51768,4346,24.13,18.72,-0.366247480632347,{"v":9.21091379692917e-09,"d":"9.21E-09"},"*",{"v":1.164194e-09,"d":"1.16E-09"},"TM7SF3","GO:0070062//extracellular exosome;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","NA","GO:0032024//positive regulation of insulin secretion;GO:0043069//negative regulation of programmed cell death;GO:0034620//cellular response to unfolded protein","K12581//CCR4-NOT transcription complex subunit 7/8;K12025//tripartite motif-containing protein 52","XP_004052943.2//PREDICTED: transmembrane 7 superfamily member 3 isoform X1 [Gorilla gorilla gorilla]","2//1"]
[9520,4364,36.99,28.73,-0.364577307591472,{"v":1.64932320450161e-13,"d":"1.65E-13"},"*",{"v":1.284436E-14,"d":"1.28E-14"},"NPEPPS","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0008237//metallopeptidase activity;GO:0004177//aminopeptidase activity;GO:0008270//zinc ion binding;GO:0042277//peptide binding;GO:0070006//metalloaminopeptidase activity","GO:0071456//cellular response to hypoxia;GO:0006508//proteolysis;GO:1903955//positive regulation of protein targeting to mitochondrion;GO:0043171//peptide catabolic process;GO:0000209//protein polyubiquitination","K08776//puromycin-sensitive aminopeptidase [EC:3.4.11.-]","XP_011901743.1//PREDICTED: puromycin-sensitive aminopeptidase isoform X1 [Cercocebus atys];NP_006301.3//puromycin-sensitive aminopeptidase isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[10772,7648,12.69,9.86,-0.364032517463194,{"v":3.41105240454915e-07,"d":"3.41E-07"},"*",{"v":5.2573e-08,"d":"5.26E-08"},"SRSF10","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0005737//cytoplasm","GO:0050733//RS domain binding;GO:0003723//RNA binding;GO:0051082//unfolded protein binding","GO:0043484//regulation of RNA splicing;GO:0006406//mRNA export from nucleus;GO:0000244//spliceosomal tri-snRNP complex assembly;GO:0006376//mRNA splice site selection;GO:0000398//mRNA splicing, via spliceosome;GO:0006355//regulation of transcription, DNA-templated;GO:0000375//RNA splicing, via transesterification reactions;GO:0016482//cytosolic transport;GO:0048025//negative regulation of mRNA splicing, via spliceosome;GO:0048024//regulation of mRNA splicing, via spliceosome","K12900//FUS-interacting serine-arginine-rich protein 1;K12891//splicing factor, arginine/serine-rich 2","BAE22485.1//unnamed protein product [Mus musculus];XP_019836877.1//PREDICTED: serine/arginine-rich splicing factor 10 isoform X1 [Bos indicus];XP_010624250.1//PREDICTED: serine/arginine-rich splicing factor 10 isoform X1 [Fukomys damarensis];NP_001177936.1//serine/arginine-rich splicing factor 10 isoform 5 [Homo sapiens];NP_006616.1//serine/arginine-rich splicing factor 10 isoform 1 [Homo sapiens];NP_001177938.1//serine/arginine-rich splicing factor 10 isoform 6 [Homo sapiens];XP_020949038.1//serine/arginine-rich splicing factor 10 isoform X3 [Sus scrofa];XP_020949037.1//serine/arginine-rich splicing factor 10 isoform X2 [Sus scrofa]","1//3;3//A2MP1;2//1;5"]
[9797,4909,17.57,13.66,-0.363156707718286,{"v":3.09397590883191e-07,"d":"3.09E-07"},"*",{"v":4.75892e-08,"d":"4.76E-08"},"TATDN2","GO:0005654//nucleoplasm","GO:0046872//metal ion binding;GO:0004536//deoxyribonuclease activity;GO:0016888//endodeoxyribonuclease activity, producing 5'-phosphomonoesters","GO:0036498//IRE1-mediated unfolded protein response;GO:0006308//DNA catabolic process","K03424//TatD DNase family protein [EC:3.1.21.-]","NP_055575.3//putative deoxyribonuclease TATDN2 [Homo sapiens]","3//A2MP1"]
[80129,5283,0.09,0.07,-0.362570079384708,0.833400693984547,"*",0.75629,"CCDC170","NA","NA","NA","K10352//myosin heavy chain","NP_079335.2//coiled-coil domain-containing protein 170 [Homo sapiens]","3//A2MP1"]
[10038,1865,16.3,12.68,-0.362317218979033,0.00408902237583893,"*",1.296794E-3,"PARP2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:1990404//protein ADP-ribosylase activity;GO:0003910//DNA ligase (ATP) activity;GO:0003950//NAD+ ADP-ribosyltransferase activity","GO:0006273//lagging strand elongation;GO:0097191//extrinsic apoptotic signaling pathway;GO:0006281//DNA repair;GO:0006284//base-excision repair;GO:0018312//peptidyl-serine ADP-ribosylation;GO:0051103//DNA ligation involved in DNA repair;GO:0006471//protein ADP-ribosylation","K10798//poly [ADP-ribose] polymerase [EC:2.4.2.30]","NP_005475.2//poly [ADP-ribose] polymerase 2 isoform 1 [Homo sapiens];NP_001036083.1//poly [ADP-ribose] polymerase 2 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[23168,5038,12.27,9.55,-0.361562610739794,{"v":1.9739944e-05,"d":"1.97E-05"},"*",{"v":4.02856e-06,"d":"4.03E-06"},"RTF1","NA","NA","NA","K15178//RNA polymerase-associated protein RTF1","XP_012621920.1//RNA polymerase-associated protein RTF1 homolog [Microcebus murinus]",4]
[92285,6210,1.49,1.16,-0.36118752533459,0.146761917361111,"*",0.0740884,"ZNF585B","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","NP_689492.3//zinc finger protein 585B [Homo sapiens]","3//A2MP1"]
[389114,5524,0.77,0.6,-0.359895945086383,0.407602568133769,"*",0.265526,"ZNF662","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","XP_015091703.1//PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein LOC102544301 [Vicugna pacos];XP_006195790.2//PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 850 [Camelus ferus]","1//3;3//A2MP1"]
[5610,4119,12.21,9.52,-0.35902972167946,0.00179220587428084,"*",0.000526532,"EIF2AK2","GO:0005840//ribosome;GO:0016020//membrane;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm","GO:0003723//RNA binding;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0004694//eukaryotic translation initiation factor 2alpha kinase activity;GO:0019888//protein phosphatase regulator activity;GO:0003725//double-stranded RNA binding;GO:0003743//translation initiation factor activity;GO:0004674//protein serine/threonine kinase activity;GO:0004672//protein kinase activity","GO:0034198//cellular response to amino acid starvation;GO:0001819//positive regulation of cytokine production;GO:0009636//response to toxic substance;GO:0017148//negative regulation of translation;GO:0045071//negative regulation of viral genome replication;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0045087//innate immune response;GO:0000186//activation of MAPKK activity;GO:0008285//negative regulation of cell proliferation;GO:1900225//regulation of NLRP3 inflammasome complex assembly;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0006468//protein phosphorylation;GO:0051607//defense response to virus;GO:0006351//transcription, DNA-templated;GO:0043066//negative regulation of apoptotic process;GO:0032874//positive regulation of stress-activated MAPK cascade;GO:0046777//protein autophosphorylation;GO:1902033//regulation of hematopoietic stem cell proliferation;GO:0033689//negative regulation of osteoblast proliferation;GO:0035455//response to interferon-alpha;GO:1901532//regulation of hematopoietic progenitor cell differentiation;GO:0010998//regulation of translational initiation by eIF2 alpha phosphorylation;GO:0006412//translation;GO:1902036//regulation of hematopoietic stem cell differentiation;GO:0030683//evasion or tolerance by virus of host immune response;GO:0042981//regulation of apoptotic process;GO:0009615//response to virus;GO:0032722//positive regulation of chemokine production","K16195//eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]","XP_014199275.1//PREDICTED: interferon-induced, double-stranded RNA-activated protein kinase isoform X1 [Pan paniscus];NP_001129124.1//interferon-induced, double-stranded RNA-activated protein kinase isoform b [Homo sapiens]","3//A2MP1;2//1"]
[153,2862,0.5,0.39,-0.358453970912476,0.64672015653897,"*",0.490364,"ADRB1","GO:0005887//integral component of plasma membrane;GO:0005622//intracellular;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005769//early endosome","GO:0005057//signal transducer activity, downstream of receptor;GO:0046982//protein heterodimerization activity;GO:0051379//epinephrine binding;GO:0051380//norepinephrine binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0031694//alpha-2A adrenergic receptor binding;GO:0004939//beta-adrenergic receptor activity;GO:0030165//PDZ domain binding;GO:0004940//beta1-adrenergic receptor activity","GO:0001659//temperature homeostasis;GO:0031649//heat generation;GO:0043547//positive regulation of GTPase activity;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0040015//negative regulation of multicellular organism growth;GO:0030819//positive regulation of cAMP biosynthetic process;GO:0043950//positive regulation of cAMP-mediated signaling;GO:0001996//positive regulation of heart rate by epinephrine-norepinephrine;GO:0002024//diet induced thermogenesis;GO:0009409//response to cold;GO:0007267//cell-cell signaling;GO:0045823//positive regulation of heart contraction;GO:0001997//positive regulation of the force of heart contraction by epinephrine-norepinephrine;GO:0071880//adenylate cyclase-activating adrenergic receptor signaling pathway;GO:0007190//activation of adenylate cyclase activity;GO:0050873//brown fat cell differentiation;GO:0002025//norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure;GO:0042596//fear response","K04141//adrenergic receptor beta-1","NP_000675.1//beta-1 adrenergic receptor [Homo sapiens]","2//1"]
[54901,3272,4.73,3.69,-0.358219367278999,0.0509925473187979,"*",0.0216688,"CDKAL1","GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0005791//rough endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0061712//tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase;GO:0046872//metal ion binding;GO:0035598//N6-threonylcarbomyladenosine methylthiotransferase activity;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0016740//transferase activity","GO:1990145//maintenance of translational fidelity;GO:0006400//tRNA modification","K15865//threonylcarbamoyladenosine tRNA methylthiotransferase CDKAL1 [EC:2.8.4.5]","NP_060244.2//threonylcarbamoyladenosine tRNA methylthiotransferase [Homo sapiens]","3//A2MP1"]
[9612,8764,59.8,46.69,-0.357031895843278,{"v":7.79570258683385e-38,"d":"7.80E-38"},"*",{"v":1.556798E-39,"d":"1.56E-39"},"NCOR2","GO:0016020//membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000785//chromatin;GO:0016363//nuclear matrix;GO:0000790//nuclear chromatin;GO:0017053//transcriptional repressor complex;GO:0016604//nuclear body;GO:0000118//histone deacetylase complex","GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0047485//protein N-terminus binding;GO:0042826//histone deacetylase binding;GO:0035259//glucocorticoid receptor binding;GO:0001012//RNA polymerase II regulatory region DNA binding;GO:0016922//ligand-dependent nuclear receptor binding;GO:0046965//retinoid X receptor binding;GO:0003682//chromatin binding;GO:0005112//Notch binding;GO:0008134//transcription factor binding;GO:0032403//protein complex binding","GO:0007595//lactation;GO:0010243//response to organonitrogen compound;GO:0006351//transcription, DNA-templated;GO:0044849//estrous cycle;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0032355//response to estradiol;GO:0019216//regulation of lipid metabolic process;GO:1903799//negative regulation of production of miRNAs involved in gene silencing by miRNA;GO:0072365//regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter","K06065//nuclear receptor co-repressor 2","NP_001193583.1//nuclear receptor corepressor 2 isoform 3 [Homo sapiens];NP_006303.4//nuclear receptor corepressor 2 isoform 1 [Homo sapiens];NP_001070729.2//nuclear receptor corepressor 2 isoform 2 [Homo sapiens]","1//3;3//A2MP1;5"]
[10308,3268,2.74,2.14,-0.35656509655938,0.157455825339035,"*",0.0806796,"ZNF267","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_012669229.1//PREDICTED: zinc finger protein 267 [Otolemur garnettii]","1//3;5"]
[25994,2785,26.05,20.36,-0.355545811090175,{"v":4.88359718378378e-06,"d":"4.88E-06"},"*",{"v":9.04936e-07,"d":"9.05E-07"},"HIGD1A","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0043234//protein complex;GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0070469//respiratory chain;GO:0005739//mitochondrion","NA","GO:0071456//cellular response to hypoxia;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0043066//negative regulation of apoptotic process;GO:0042149//cellular response to glucose starvation;GO:0055114//oxidation-reduction process;GO:0090201//negative regulation of release of cytochrome c from mitochondria","K12581//CCR4-NOT transcription complex subunit 7/8;K17985//activating molecule in BECN1-regulated autophagy protein 1","NP_001093138.1//HIG1 domain family member 1A, mitochondrial isoform a [Homo sapiens]","1//3;3//A2MP1"]
[101929372,1838,4.59,3.59,-0.354510309590757,0.205296322236459,"*",0.1103336,"LOC101929372","NA","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K15107//solute carrier family 25 (mitochondrial glutamate transporter), member 18/22","NP_001275636.1//uncharacterized protein LOC101929372 [Homo sapiens]","1//3"]
[1109,1192,0.23,0.18,-0.353636954614701,0.782707832243389,"*",0.689316,"AKR1C4","NA","NA","NA","K00037//3alpha-hydroxysteroid 3-dehydrogenase / chlordecone reductase [EC:1.1.1.50 1.1.1.357 1.1.1.225];K04119//aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]","XP_017716094.1//PREDICTED: aldo-keto reductase family 1 member C4 [Rhinopithecus bieti]","3//A2MP1"]
[8120,3982,0.6,0.47,-0.352301743930881,0.852857781151689,"*",0.780674,"AP3B2","GO:1904115//axon cytoplasm;GO:0030131//clathrin adaptor complex;GO:0030123//AP-3 adaptor complex","NA","GO:0006886//intracellular protein transport;GO:0048490//anterograde synaptic vesicle transport;GO:0016192//vesicle-mediated transport","K12397//AP-3 complex subunit beta","XP_021796519.1//AP-3 complex subunit beta-2 isoform X4 [Papio anubis];XP_011809281.1//PREDICTED: AP-3 complex subunit beta-2 isoform X3 [Colobus angolensis palliatus];XP_001082801.1//PREDICTED: AP-3 complex subunit beta-2 [Macaca mulatta];XP_011809278.1//PREDICTED: AP-3 complex subunit beta-2 isoform X1 [Colobus angolensis palliatus];XP_004056719.1//PREDICTED: AP-3 complex subunit beta-2 isoform X2 [Gorilla gorilla gorilla]","4;1//3"]
[91862,2428,3.14,2.46,-0.352106243552387,0.24933836408326,"*",0.1409806,"MARVELD3","GO:0031410//cytoplasmic vesicle;GO:0016021//integral component of membrane;GO:0005923//bicellular tight junction","GO:0031435//mitogen-activated protein kinase kinase kinase binding","GO:0045216//cell-cell junction organization;GO:1902414//protein localization to cell junction;GO:0070830//bicellular tight junction assembly;GO:0006970//response to osmotic stress;GO:0046329//negative regulation of JNK cascade;GO:0050680//negative regulation of epithelial cell proliferation;GO:0010633//negative regulation of epithelial cell migration","K21099//MARVEL domain-containing protein 3","XP_016785621.1//PREDICTED: MARVEL domain-containing protein 3 isoform X1 [Pan troglodytes];XP_016785622.1//PREDICTED: MARVEL domain-containing protein 3 isoform X2 [Pan troglodytes];NP_001017967.2//MARVEL domain-containing protein 3 isoform 1 [Homo sapiens]","1//3;3//A2MP1;5"]
[2151,3446,11.07,8.68,-0.350888274337073,0.000914488082995038,"*",0.00025384,"F2RL2","GO:0005887//integral component of plasma membrane;GO:0016324//apical plasma membrane;GO:0043234//protein complex;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0004435//phosphatidylinositol phospholipase C activity;GO:0015057//thrombin-activated receptor activity;GO:0004930//G-protein coupled receptor activity","GO:0009611//response to wounding;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway;GO:0035025//positive regulation of Rho protein signal transduction;GO:0007596//blood coagulation;GO:0030168//platelet activation","K04235//coagulation factor II (thrombin) receptor-like 2","NP_004092.1//proteinase-activated receptor 3 isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[89932,5849,2.09,1.64,-0.349807127462799,0.103448943637575,"*",0.048603,"PAPLN","GO:0005576//extracellular region","GO:0008233//peptidase activity;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding","NA","K08621//a disintegrin and metalloproteinase with thrombospondin motifs 6 [EC:3.4.24.-]","NP_775733.3//papilin precursor [Homo sapiens]","3//A2MP1"]
[51099,4062,3.58,2.81,-0.34938945704333,0.291994632241435,"*",0.1701992,"ABHD5","GO:0005811//lipid droplet;GO:0005829//cytosol","GO:0016787//hydrolase activity;GO:0003841//1-acylglycerol-3-phosphate O-acyltransferase activity;GO:0042171//lysophosphatidic acid acyltransferase activity","GO:0010891//negative regulation of sequestering of triglyceride;GO:0010898//positive regulation of triglyceride catabolic process;GO:0030154//cell differentiation;GO:0006631//fatty acid metabolic process;GO:0051006//positive regulation of lipoprotein lipase activity;GO:0006629//lipid metabolic process;GO:0006654//phosphatidic acid biosynthetic process","K13699//abhydrolase domain-containing protein 5 [EC:2.3.1.51]","NP_057090.2//1-acylglycerol-3-phosphate O-acyltransferase ABHD5 [Homo sapiens]","1//3;5"]
[23741,2096,36.88,28.96,-0.348777053346133,{"v":3.99156774982818e-06,"d":"3.99E-06"},"*",{"v":7.27148e-07,"d":"7.27E-07"},"EID1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0036464//cytoplasmic ribonucleoprotein granule","GO:0003714//transcription corepressor activity;GO:0035034//histone acetyltransferase regulator activity;GO:0035035//histone acetyltransferase binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0035065//regulation of histone acetylation;GO:0030154//cell differentiation;GO:0006351//transcription, DNA-templated;GO:0007049//cell cycle;GO:0045595//regulation of cell differentiation","K17449//SHC-transforming protein 4","NP_055150.1//EP300-interacting inhibitor of differentiation 1 [Homo sapiens]","2//1"]
[2799,5144,27.02,21.23,-0.347923303420307,{"v":2.53402511789348e-10,"d":"2.53E-10"},"*",{"v":2.65078e-11,"d":"2.65E-11"},"GNS","GO:0070062//extracellular exosome;GO:0035578//azurophil granule lumen;GO:0043202//lysosomal lumen;GO:1904813//ficolin-1-rich granule lumen;GO:0005576//extracellular region;GO:0005764//lysosome","GO:0046872//metal ion binding;GO:0008484//sulfuric ester hydrolase activity;GO:0008449//N-acetylglucosamine-6-sulfatase activity","GO:0042340//keratan sulfate catabolic process;GO:0043312//neutrophil degranulation;GO:0006027//glycosaminoglycan catabolic process;GO:0030203//glycosaminoglycan metabolic process","K01137//N-acetylglucosamine-6-sulfatase [EC:3.1.6.14]","NP_002067.1//N-acetylglucosamine-6-sulfatase precursor [Homo sapiens]","3//A2MP1"]
[130497,1911,10.43,8.2,-0.34704334301432,0.0314715974614173,"*",0.01251062,"OSR1","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","XP_020386293.1//zinc finger protein 208-like [Rhincodon typus]","2//1"]
[84445,2806,29.03,22.84,-0.345981921263819,{"v":2.06323358099352e-06,"d":"2.06E-06"},"*",{"v":3.58812e-07,"d":"3.59E-07"},"LZTS2","GO:0005815//microtubule organizing center;GO:0005874//microtubule;GO:0005829//cytosol;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0031982//vesicle;GO:0005886//plasma membrane;GO:0030496//midbody","NA","GO:0001822//kidney development;GO:0030178//negative regulation of Wnt signaling pathway;GO:0000910//cytokinesis;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0051168//nuclear export;GO:0051301//cell division;GO:1900181//negative regulation of protein localization to nucleus;GO:0016055//Wnt signaling pathway;GO:0051255//spindle midzone assembly;GO:0051013//microtubule severing;GO:0007049//cell cycle;GO:0008285//negative regulation of cell proliferation","K03006//DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6];K21882//PDZ domain-containing protein 7","NP_115805.1//leucine zipper putative tumor suppressor 2 isoform a [Homo sapiens];NP_001305030.1//leucine zipper putative tumor suppressor 2 isoform b [Homo sapiens]","1//3;3//A2MP1"]
[54888,3338,33.54,26.4,-0.345344759318531,{"v":9.95210131558185e-09,"d":"9.95E-09"},"*",{"v":1.263482e-09,"d":"1.26E-09"},"NSUN2","GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0033391//chromatoid body;GO:0005819//spindle;GO:0005737//cytoplasm","GO:0016428//tRNA (cytosine-5-)-methyltransferase activity;GO:0003723//RNA binding;GO:0000049//tRNA binding","GO:0048820//hair follicle maturation;GO:0051301//cell division;GO:0006400//tRNA modification;GO:0030488//tRNA methylation;GO:0033313//meiotic cell cycle checkpoint;GO:0007286//spermatid development","K15335//tRNA (cytosine34-C5)-methyltransferase [EC:2.1.1.203]","NP_060225.4//tRNA (cytosine(34)-C(5))-methyltransferase isoform 1 [Homo sapiens];NP_001180384.1//tRNA (cytosine(34)-C(5))-methyltransferase isoform 2 [Homo sapiens]","1//3;5"]
[56889,6140,31.76,25,-0.345282817593508,{"v":5.69972369942197e-14,"d":"5.70E-14"},"*",{"v":4.321e-15,"d":"4.32E-15"},"TM9SF3","GO:0016021//integral component of membrane","NA","NA","K17087//transmembrane 9 superfamily member 3","BAD90204.1//mKIAA4036 protein, partial [Mus musculus]","3//A2MP1"]
[420,5167,0.33,0.26,-0.343954401217361,0.578802215606986,"*",0.421148,"ART4","GO:0016020//membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0031225//anchored component of membrane","GO:0003956//NAD(P)+-protein-arginine ADP-ribosyltransferase activity","GO:0006525//arginine metabolic process;GO:0006501//C-terminal protein lipidation;GO:0006471//protein ADP-ribosylation","K06717//ADP-ribosyltransferase 4 [EC:2.4.2.31]","NP_066549.2//ecto-ADP-ribosyltransferase 4 isoform 1 precursor [Homo sapiens];NP_001341575.1//ecto-ADP-ribosyltransferase 4 isoform 2 precursor [Homo sapiens]","1//3;3//A2MP1"]
[23064,11163,3.35,2.64,-0.343623165986681,0.00178554654615221,"*",0.000524352,"SETX","GO:0030424//axon;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000781//chromosome, telomeric region;GO:0005737//cytoplasm;GO:0045171//intercellular bridge;GO:0000228//nuclear chromosome;GO:0030426//growth cone;GO:0005730//nucleolus;GO:0016604//nuclear body","GO:0003677//DNA binding;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0001147//transcription termination site sequence-specific DNA binding;GO:0003678//DNA helicase activity","GO:0006396//RNA processing;GO:0033120//positive regulation of RNA splicing;GO:0006376//mRNA splice site selection;GO:0006369//termination of RNA polymerase II transcription;GO:0043491//protein kinase B signaling;GO:0007283//spermatogenesis;GO:0006302//double-strand break repair;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0006974//cellular response to DNA damage stimulus;GO:0070301//cellular response to hydrogen peroxide;GO:2000806//positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled;GO:0007623//circadian rhythm;GO:0006353//DNA-templated transcription, termination;GO:0000165//MAPK cascade;GO:0043066//negative regulation of apoptotic process;GO:2000144//positive regulation of DNA-templated transcription, initiation;GO:0010976//positive regulation of neuron projection development;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0060566//positive regulation of DNA-templated transcription, termination;GO:0071300//cellular response to retinoic acid;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0034599//cellular response to oxidative stress;GO:0006310//DNA recombination","K10706//senataxin [EC:3.6.4.-]","NP_001338457.1//probable helicase senataxin isoform 2 [Homo sapiens];NP_055861.3//probable helicase senataxin isoform 1 [Homo sapiens]","6;1//3"]
[2054,3282,16.77,13.22,-0.343160512056654,{"v":6.35363721626929e-05,"d":"6.35E-05"},"*",{"v":1.417974E-5,"d":"1.42E-05"},"STX2","GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0016323//basolateral plasma membrane;GO:0005615//extracellular space;GO:0008021//synaptic vesicle;GO:0005622//intracellular;GO:0030027//lamellipodium;GO:0016021//integral component of membrane;GO:0031201//SNARE complex;GO:0005886//plasma membrane","GO:0000149//SNARE binding;GO:0005484//SNAP receptor activity;GO:0048306//calcium-dependent protein binding;GO:0046983//protein dimerization activity","GO:0031629//synaptic vesicle fusion to presynaptic active zone membrane;GO:0007165//signal transduction;GO:0030154//cell differentiation;GO:0033194//response to hydroperoxide;GO:1903575//cornified envelope assembly;GO:0016192//vesicle-mediated transport;GO:0007398//ectoderm development;GO:0006886//intracellular protein transport;GO:0030193//regulation of blood coagulation;GO:0007340//acrosome reaction;GO:0009887//animal organ morphogenesis;GO:0048278//vesicle docking;GO:0051259//protein oligomerization","K08486//syntaxin 1B/2/3","NP_001337980.1//syntaxin-2 isoform 5 [Homo sapiens];NP_001337978.1//syntaxin-2 isoform 3 [Homo sapiens];NP_001337979.1//syntaxin-2 isoform 4 [Homo sapiens];NP_001971.2//syntaxin-2 isoform 1 [Homo sapiens];NP_919337.1//syntaxin-2 isoform 2 [Homo sapiens]","4;1//3;3//A2MP1"]
[56667,2899,2.23,1.76,-0.341468281283007,0.281600332871073,"*",0.1627126,"MUC13","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0016324//apical plasma membrane;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005796//Golgi lumen","GO:0042803//protein homodimerization activity","GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0016266//O-glycan processing;GO:0030277//maintenance of gastrointestinal epithelium","K17298//mucin-13","NP_149038.3//mucin-13 precursor [Homo sapiens]","3//A2MP1"]
[84133,6575,6.93,5.47,-0.341314519344657,0.000612142793549895,"*",1.639764E-4,"ZNRF3","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0061630//ubiquitin protein ligase activity;GO:0046872//metal ion binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005109//frizzled binding","GO:0030178//negative regulation of Wnt signaling pathway;GO:0016567//protein ubiquitination;GO:2000051//negative regulation of non-canonical Wnt signaling pathway;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0060070//canonical Wnt signaling pathway;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0072089//stem cell proliferation;GO:0038018//Wnt receptor catabolic process","K16273//E3 ubiquitin-protein ligase ZNRF3 [EC:2.3.2.27]","NP_001193927.1//E3 ubiquitin-protein ligase ZNRF3 isoform 1 precursor [Homo sapiens];XP_011528737.1//PREDICTED: E3 ubiquitin-protein ligase ZNRF3 isoform X1 [Homo sapiens]","1//3;3//A2MP1"]
[26064,4967,21.56,17.02,-0.341126141066543,{"v":5.84862720214669e-08,"d":"5.85E-08"},"*",{"v":8.18676e-09,"d":"8.19E-09"},"RAI14","GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0005938//cell cortex;GO:0005829//cytosol;GO:0001650//fibrillar center;GO:0030054//cell junction;GO:0005739//mitochondrion","NA","GO:0030154//cell differentiation;GO:0007283//spermatogenesis","K15503//serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B;K21440//ankyrin repeat domain-containing protein 50","NP_001138994.1//ankycorbin isoform b [Homo sapiens];NP_056392.2//ankycorbin isoform a [Homo sapiens];NP_001138997.1//ankycorbin isoform d [Homo sapiens];NP_001138995.1//ankycorbin isoform c [Homo sapiens]","1//3;2//1"]
[285343,2236,6.14,4.85,-0.340253908295689,0.0792002371214226,"*",0.0356882,"TCAIM","GO:0005739//mitochondrion","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K09228//KRAB domain-containing zinc finger protein","NP_776187.2//T-cell activation inhibitor, mitochondrial isoform 1 [Homo sapiens];NP_001025011.1//T-cell activation inhibitor, mitochondrial isoform 2 [Homo sapiens];XP_011889429.1//PREDICTED: T-cell activation inhibitor, mitochondrial isoform X1 [Cercocebus atys]","1//3;3//A2MP1;2//1"]
[7175,9727,12.01,9.49,-0.339756158684525,{"v":1.61449914518448e-08,"d":"1.61E-08"},"*",{"v":2.10934e-09,"d":"2.11E-09"},"TPR","NA","NA","NA","K09291//nucleoprotein TPR","XP_003815642.1//PREDICTED: nucleoprotein TPR [Pan paniscus]","2//1"]
[6619,3095,9.41,7.44,-0.338892101620505,0.00836428337144965,"*",2.83906E-3,"SNAPC3","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0016604//nuclear body","GO:0003677//DNA binding","GO:0042795//snRNA transcription from RNA polymerase II promoter;GO:0009301//snRNA transcription;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006383//transcription from RNA polymerase III promoter;GO:0006366//transcription from RNA polymerase II promoter","K15210//snRNA-activating protein complex subunit 3","NP_001034786.1//snRNA-activating protein complex subunit 3 [Homo sapiens]","1//3"]
[55218,4894,6.6,5.22,-0.338416217675931,2.98756937908629E-3,"*",0.000921108,"EXD2","GO:0005634//nucleus;GO:0016021//integral component of membrane;GO:0005737//cytoplasm","GO:0008408//3'-5' exonuclease activity;GO:0008310//single-stranded DNA 3'-5' exodeoxyribonuclease activity;GO:0008852//exodeoxyribonuclease I activity;GO:0003676//nucleic acid binding","GO:0006302//double-strand break repair;GO:0000729//DNA double-strand break processing;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0000724//double-strand break repair via homologous recombination","K20777//exonuclease 3'-5' domain-containing protein 2 [EC:3.1.11.1]","NP_001180289.1//exonuclease 3'-5' domain-containing protein 2 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[23627,4038,1.39,1.1,-0.337581359198848,0.355808283612587,"*",0.21802,"PRND","GO:0031362//anchored component of external side of plasma membrane;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0005507//copper ion binding","GO:0006501//C-terminal protein lipidation;GO:0007340//acrosome reaction;GO:0006878//cellular copper ion homeostasis;GO:0051260//protein homooligomerization","K12581//CCR4-NOT transcription complex subunit 7/8;K11447//histone demethylase [EC:1.14.11.-]","XP_003779349.1//PREDICTED: LOW QUALITY PROTEIN: prion-like protein doppel [Pongo abelii]","3//A2MP1"]
[64682,7753,15.79,12.5,-0.337083076310787,{"v":9.63561772161895e-09,"d":"9.64E-09"},"*",{"v":1.222096e-09,"d":"1.22E-09"},"ANAPC1","GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005680//anaphase-promoting complex","NA","GO:0070979//protein K11-linked ubiquitination;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0051301//cell division;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle","K03348//anaphase-promoting complex subunit 1","NP_073153.1//anaphase-promoting complex subunit 1 [Homo sapiens]","3//A2MP1"]
[23150,6514,0.24,0.19,-0.337034987277571,0.626495524277141,"*",0.503228,"FRMD4B","GO:0001726//ruffle;GO:0005856//cytoskeleton;GO:0005615//extracellular space;GO:0005923//bicellular tight junction;GO:0005737//cytoplasm;GO:0005912//adherens junction","NA","GO:0090162//establishment of epithelial cell polarity","K05762//radixin;K05763//moesin","NP_055938.1//FERM domain-containing protein 4B [Homo sapiens]","2//1"]
[2000,4112,21,16.64,-0.335733894412393,{"v":3.04339912106368E-6,"d":"3.04E-06"},"*",{"v":5.44512e-07,"d":"5.45E-07"},"ELF4","GO:0005634//nucleus;GO:0016605//PML body;GO:0005654//nucleoplasm;GO:0016604//nuclear body","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0001787//natural killer cell proliferation;GO:0030154//cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0001866//NK T cell proliferation;GO:0045087//innate immune response;GO:0045893//positive regulation of transcription, DNA-templated","K09428//E74-like factor 1/2/4","NP_001412.1//ETS-related transcription factor Elf-4 [Homo sapiens]","1//3;3//A2MP1"]
[23197,4515,22.17,17.57,-0.335494578858931,{"v":3.05447094865526e-07,"d":"3.05E-07"},"*",{"v":4.69242e-08,"d":"4.69E-08"},"FAF2","GO:0034098//VCP-NPL4-UFD1 AAA ATPase complex;GO:0005783//endoplasmic reticulum;GO:0035578//azurophil granule lumen;GO:0005811//lipid droplet;GO:0005576//extracellular region","GO:0035473//lipase binding;GO:0043130//ubiquitin binding;GO:0055102//lipase inhibitor activity;GO:0031625//ubiquitin protein ligase binding","GO:0030970//retrograde protein transport, ER to cytosol;GO:0006986//response to unfolded protein;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0043312//neutrophil degranulation;GO:0034389//lipid particle organization","K18726//FAS-associated factor 2","XP_008845544.1//PREDICTED: FAS-associated factor 2 [Nannospalax galili]","2//1"]
[10206,6947,3.38,2.68,-0.334790245824412,0.0236339009081999,"*",0.00905764,"TRIM13","GO:0097038//perinuclear endoplasmic reticulum;GO:0005622//intracellular;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0044322//endoplasmic reticulum quality control compartment;GO:0005737//cytoplasm","GO:0008270//zinc ion binding;GO:0004871//signal transducer activity;GO:1904264//ubiquitin protein ligase activity involved in ERAD pathway;GO:0004842//ubiquitin-protein transferase activity","GO:0009653//anatomical structure morphogenesis;GO:1904380//endoplasmic reticulum mannose trimming;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0051260//protein homooligomerization;GO:1902187//negative regulation of viral release from host cell;GO:0010332//response to gamma radiation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0016239//positive regulation of macroautophagy;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0051865//protein autoubiquitination;GO:0032897//negative regulation of viral transcription;GO:0045087//innate immune response;GO:0010942//positive regulation of cell death","K12003//tripartite motif-containing protein 13 [EC:2.3.2.27]","NP_001007279.1//E3 ubiquitin-protein ligase TRIM13 isoform 2 [Homo sapiens]","4;3//A2MP1;2//1"]
[100528020,1561,1.5,1.19,-0.334000927187937,0.570687410628019,"*",0.414136,"FAM187A","NA","NA","NA","NA","NP_001245329.1//Ig-like V-type domain-containing protein FAM187A precursor [Homo sapiens]","1//3"]
[1314,5640,35.19,27.93,-0.333349940469715,{"v":2.62691674132492e-13,"d":"2.63E-13"},"*",{"v":2.08522e-14,"d":"2.09E-14"},"COPA","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0030126//COPI vesicle coat;GO:0005737//cytoplasm;GO:0000139//Golgi membrane;GO:0030133//transport vesicle;GO:0005829//cytosol;GO:0005789//endoplasmic reticulum membrane","GO:0005198//structural molecule activity;GO:0005179//hormone activity","GO:0006886//intracellular protein transport;GO:0030157//pancreatic juice secretion;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0016192//vesicle-mediated transport","K05236//coatomer subunit alpha","NP_001091868.1//coatomer subunit alpha isoform 1 [Homo sapiens];NP_004362.2//coatomer subunit alpha isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[83943,1256,6.75,5.36,-0.332654501480421,0.101868418983957,"*",0.047701,"IMMP2L","GO:0042720//mitochondrial inner membrane peptidase complex;GO:0016021//integral component of membrane","GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity","GO:0006801//superoxide metabolic process;GO:0006627//protein processing involved in protein targeting to mitochondrion;GO:0007283//spermatogenesis;GO:0030728//ovulation;GO:0001541//ovarian follicle development;GO:0007420//brain development;GO:0006465//signal peptide processing;GO:0008015//blood circulation;GO:0022904//respiratory electron transport chain;GO:0061300//cerebellum vasculature development;GO:0006974//cellular response to DNA damage stimulus;GO:0033108//mitochondrial respiratory chain complex assembly","K09648//mitochondrial inner membrane protease subunit 2 [EC:3.4.21.-]","XP_006071827.1//PREDICTED: mitochondrial inner membrane protease subunit 2-like isoform X1 [Bubalus bubalis];XP_009000957.1//PREDICTED: mitochondrial inner membrane protease subunit 2 isoform X1 [Callithrix jacchus];NP_115938.1//mitochondrial inner membrane protease subunit 2 isoform a [Homo sapiens];XP_006071829.1//PREDICTED: mitochondrial inner membrane protease subunit 2-like isoform X3 [Bubalus bubalis];NP_001337890.1//mitochondrial inner membrane protease subunit 2 isoform b [Homo sapiens]","1//3;3//A2MP1"]
[2048,11054,13.07,10.38,-0.332452697437552,{"v":6.37548766571916e-10,"d":"6.38E-10"},"*",{"v":7.02046e-11,"d":"7.02E-11"},"EPHB2","GO:0030425//dendrite;GO:0030424//axon;GO:0005634//nucleus;GO:0098794//postsynapse;GO:0043025//neuronal cell body;GO:0005887//integral component of plasma membrane;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0001540//amyloid-beta binding;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0005102//receptor binding;GO:0008046//axon guidance receptor activity;GO:0044877//macromolecular complex binding;GO:0004713//protein tyrosine kinase activity;GO:0005003//ephrin receptor activity;GO:0005005//transmembrane-ephrin receptor activity","GO:0031290//retinal ganglion cell axon guidance;GO:0016310//phosphorylation;GO:1904782//negative regulation of NMDA glutamate receptor activity;GO:0051965//positive regulation of synapse assembly;GO:0060997//dendritic spine morphogenesis;GO:0042472//inner ear morphogenesis;GO:1903078//positive regulation of protein localization to plasma membrane;GO:0031915//positive regulation of synaptic plasticity;GO:0007411//axon guidance;GO:0021631//optic nerve morphogenesis;GO:0022038//corpus callosum development;GO:0001525//angiogenesis;GO:0048013//ephrin receptor signaling pathway;GO:0010628//positive regulation of gene expression;GO:0048170//positive regulation of long-term neuronal synaptic plasticity;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0001933//negative regulation of protein phosphorylation;GO:0050771//negative regulation of axonogenesis;GO:0106028//neuron projection retraction;GO:0007399//nervous system development;GO:0046580//negative regulation of Ras protein signal transduction;GO:0050878//regulation of body fluid levels;GO:0048593//camera-type eye morphogenesis;GO:0051389//inactivation of MAPKK activity;GO:0048168//regulation of neuronal synaptic plasticity;GO:0071679//commissural neuron axon guidance;GO:0060021//palate development;GO:0007611//learning or memory;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0007413//axonal fasciculation;GO:1900273//positive regulation of long-term synaptic potentiation;GO:1904783//positive regulation of NMDA glutamate receptor activity;GO:0001655//urogenital system development;GO:0099557//trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission;GO:0060996//dendritic spine development;GO:0007612//learning;GO:0021952//central nervous system projection neuron axonogenesis","K05111//Eph receptor B2 [EC:2.7.10.1]","EAW95024.1//EPH receptor B2, isoform CRA_c [Homo sapiens];NP_001296121.1//ephrin type-B receptor 2 isoform 3 precursor [Homo sapiens];XP_003415418.1//PREDICTED: ephrin type-B receptor 2 isoform X1 [Loxodonta africana]","1//3;4;7"]
[10163,5721,23.64,18.78,-0.332032972523758,{"v":2.48059226382979e-09,"d":"2.48E-09"},"*",{"v":2.91944e-10,"d":"2.92E-10"},"WASF2","GO:0005856//cytoskeleton;GO:0031209//SCAR complex;GO:0070062//extracellular exosome;GO:0005622//intracellular;GO:0030027//lamellipodium;GO:0001726//ruffle;GO:0005911//cell-cell junction;GO:0005829//cytosol;GO:0043234//protein complex;GO:0015629//actin cytoskeleton;GO:0005769//early endosome","GO:0003779//actin binding;GO:0051018//protein kinase A binding;GO:0017124//SH3 domain binding;GO:0032403//protein complex binding;GO:0045296//cadherin binding","GO:0030032//lamellipodium assembly;GO:0030048//actin filament-based movement;GO:0035855//megakaryocyte development;GO:0001525//angiogenesis;GO:0030036//actin cytoskeleton organization;GO:0016032//viral process;GO:0001667//ameboidal-type cell migration;GO:0016601//Rac protein signal transduction;GO:0051497//negative regulation of stress fiber assembly;GO:0010592//positive regulation of lamellipodium assembly;GO:0006897//endocytosis;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0072673//lamellipodium morphogenesis;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway","K05748//WAS protein family, member 2","NP_001188333.1//wiskott-Aldrich syndrome protein family member 2 isoform 2 [Homo sapiens];NP_008921.1//wiskott-Aldrich syndrome protein family member 2 isoform 1 [Homo sapiens]","4;2//1"]
[113235,6480,10.73,8.53,-0.331032429438232,{"v":2.78278983129657E-5,"d":"2.78E-05"},"*",{"v":5.84466e-06,"d":"5.84E-06"},"SLC46A1","GO:0009986//cell surface;GO:0016324//apical plasma membrane;GO:0031526//brush border membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0015232//heme transporter activity;GO:0005542//folic acid binding;GO:0015350//methotrexate transmembrane transporter activity;GO:0008517//folic acid transmembrane transporter activity;GO:0015078//hydrogen ion transmembrane transporter activity;GO:0005215//transporter activity","GO:0006879//cellular iron ion homeostasis;GO:0055085//transmembrane transport;GO:0015884//folic acid transport;GO:1902600//hydrogen ion transmembrane transport;GO:1904447//folic acid import across plasma membrane;GO:0051958//methotrexate transport;GO:0046655//folic acid metabolic process;GO:0098829//intestinal folate absorption","K14613//MFS transporter, PCFT/HCP family, solute carrier family 46 (folate transporter), member 1","XP_011927771.1//PREDICTED: proton-coupled folate transporter isoform X1 [Cercocebus atys]","2//1;5"]
[727897,17916,0.44,0.35,-0.330148601692331,0.22403118772191,"*",0.12245,"MUC5B","GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005796//Golgi lumen","NA","GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0016266//O-glycan processing","K13908//mucin-5B","NP_002449.2//mucin-5B precursor [Homo sapiens]","2//1"]
[51175,2314,2.35,1.87,-0.329622486677363,0.346679106483868,"*",0.210538,"TUBE1","GO:0005874//microtubule","GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0007017//microtubule-based process","K10391//tubulin epsilon","XP_003822260.2//PREDICTED: tubulin epsilon chain isoform X1 [Pan paniscus]",4]
[9221,3950,56.07,44.64,-0.328892042637127,{"v":2.15987385763293e-14,"d":"2.16E-14"},"*",{"v":1.57657e-15,"d":"1.58E-15"},"NOLC1","GO:0005730//nucleolus;GO:0015030//Cajal body;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0005524//ATP binding;GO:0001042//RNA polymerase I core binding;GO:0046982//protein heterodimerization activity;GO:0005525//GTP binding","GO:0014032//neural crest cell development;GO:0000278//mitotic cell cycle;GO:0006364//rRNA processing;GO:0006417//regulation of translation;GO:0007409//axonogenesis;GO:0007000//nucleolus organization;GO:0014029//neural crest formation;GO:0007049//cell cycle;GO:0048167//regulation of synaptic plasticity","K11294//nucleolin","NP_001271318.1//nucleolar and coiled-body phosphoprotein 1 isoform 3 [Homo sapiens];NP_004732.2//nucleolar and coiled-body phosphoprotein 1 isoform 2 [Homo sapiens];NP_001271317.1//nucleolar and coiled-body phosphoprotein 1 isoform 1 [Homo sapiens]","1//3;4"]
[4735,3356,121.57,96.83,-0.328261257241867,{"v":6.96161665230769e-29,"d":"6.96E-29"},"*",{"v":1.982932E-30,"d":"1.98E-30"},"2019-09-02","GO:0060170//ciliary membrane;GO:0097227//sperm annulus;GO:0005737//cytoplasm;GO:0097730//non-motile cilium;GO:0030496//midbody;GO:0005730//nucleolus;GO:0000145//exocyst;GO:0005829//cytosol;GO:0005819//spindle;GO:0015629//actin cytoskeleton;GO:0000777//condensed chromosome kinetochore;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0032391//photoreceptor connecting cilium;GO:0048471//perinuclear region of cytoplasm;GO:0031105//septin complex;GO:0032154//cleavage furrow;GO:0005930//axoneme","GO:0042802//identical protein binding;GO:0005525//GTP binding;GO:0045296//cadherin binding","GO:0060271//cilium assembly;GO:0051301//cell division;GO:0031175//neuron projection development;GO:0007224//smoothened signaling pathway;GO:0007283//spermatogenesis;GO:0007049//cell cycle","K16942//septin 2","XP_011851768.1//PREDICTED: septin-2 isoform X2 [Mandrillus leucophaeus];XP_012354745.1//PREDICTED: septin-2 isoform X1 [Nomascus leucogenys];EHH21840.1//hypothetical protein EGK_04994 [Macaca mulatta];NP_001336216.1//septin-2 isoform e [Homo sapiens];XP_020930254.1//septin-2 isoform X1 [Sus scrofa];XP_008136700.1//PREDICTED: septin-2 isoform X1 [Eptesicus fuscus];XP_016859680.1//PREDICTED: septin-2 isoform X3 [Homo sapiens];NP_001269901.1//septin-2 isoform b [Homo sapiens];XP_011851766.1//PREDICTED: septin-2 isoform X1 [Mandrillus leucophaeus];NP_001307958.1//septin-2 isoform d [Homo sapiens];NP_001269902.1//septin-2 isoform c [Homo sapiens]","4;1//3;2//1"]
[27069,2449,98.19,78.24,-0.327669732813686,{"v":2.40898520258065e-15,"d":"2.41E-15"},"*",{"v":1.636252e-16,"d":"1.64E-16"},"GHITM","GO:0070062//extracellular exosome;GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion","NA","GO:0006915//apoptotic process","K21890//growth hormone-inducible transmembrane protein","NP_055209.2//growth hormone-inducible transmembrane protein [Homo sapiens]","2//1"]
[2796,2166,0.69,0.55,-0.327164743253509,0.815051180887372,"*",0.732546,"GNRH1","GO:0030425//dendrite;GO:0005615//extracellular space;GO:0043204//perikaryon;GO:1990008//neurosecretory vesicle;GO:0005576//extracellular region;GO:0005798//Golgi-associated vesicle;GO:0043679//axon terminus;GO:0005739//mitochondrion;GO:0098556//cytoplasmic side of rough endoplasmic reticulum membrane","GO:0005183//gonadotropin hormone-releasing hormone activity;GO:0005179//hormone activity","GO:0010468//regulation of gene expression;GO:1990637//response to prolactin;GO:0030238//male sex determination;GO:0034695//response to prostaglandin E;GO:0032496//response to lipopolysaccharide;GO:0044849//estrous cycle;GO:0045471//response to ethanol;GO:2000354//regulation of ovarian follicle development;GO:0033574//response to testosterone;GO:0033087//negative regulation of immature T cell proliferation;GO:0008285//negative regulation of cell proliferation;GO:0007565//female pregnancy;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0043066//negative regulation of apoptotic process;GO:0007568//aging;GO:0048545//response to steroid hormone;GO:0031960//response to corticosteroid;GO:0035864//response to potassium ion;GO:2001223//negative regulation of neuron migration;GO:0007275//multicellular organism development","K05252//gonadotropin-releasing hormone","NP_000816.4//progonadoliberin-1 isoform 1 precursor [Homo sapiens];XP_017741013.1//PREDICTED: progonadoliberin-1 isoform X1 [Rhinopithecus bieti]","1//3;3//A2MP1"]
[144100,5165,5.67,4.52,-0.327025962527041,0.0089382416046895,"*",0.00305458,"PLEKHA7","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005813//centrosome;GO:0030054//cell junction;GO:0005915//zonula adherens","GO:0070097//delta-catenin binding","GO:0045218//zonula adherens maintenance;GO:0090136//epithelial cell-cell adhesion","K05633//atrophin-1 interacting protein 5 (WW domain containing E3 ubiquitin protein ligase 1) [EC:2.3.2.26];K06245//laminin, beta 4;K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K02927//large subunit ribosomal protein L40e;K17985//activating molecule in BECN1-regulated autophagy protein 1;K15696//RING finger protein 113B","NP_778228.3//pleckstrin homology domain-containing family A member 7 isoform 2 [Homo sapiens];NP_001316560.1//pleckstrin homology domain-containing family A member 7 isoform 3 [Homo sapiens];NP_001316559.1//pleckstrin homology domain-containing family A member 7 isoform 1 [Homo sapiens]","4;1//3"]
[10009,5225,4.89,3.9,-0.326360341202623,0.0200096602736069,"*",0.00750832,"ZBTB33","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0046872//metal ion binding;GO:0043565//sequence-specific DNA binding;GO:0008327//methyl-CpG binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0016055//Wnt signaling pathway;GO:0006351//transcription, DNA-templated;GO:0035556//intracellular signal transduction","K10507//zinc finger and BTB domain-containing protein 33","NP_006768.1//transcriptional regulator Kaiso [Homo sapiens]","1//3;3//A2MP1"]
[58499,10402,1.09,0.87,-0.325240828928198,0.132266096022295,"*",0.065363,"ZNF462","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003676//nucleic acid binding","GO:0043392//negative regulation of DNA binding;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006325//chromatin organization;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","XP_021570276.1//zinc finger protein 462 isoform X3 [Carlito syrichta];NP_067047.4//zinc finger protein 462 isoform 1 [Homo sapiens]","1//3;5"]
[55610,3878,1.54,1.23,-0.324272035355662,0.529452312655087,"*",0.374004,"VPS50","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:1990745//EARP complex;GO:0055037//recycling endosome","GO:0000149//SNARE binding","GO:0032456//endocytic recycling;GO:0015031//protein transport","NA","NP_060137.2//syndetin isoform a [Homo sapiens];BAB47490.2//KIAA1861 protein, partial [Homo sapiens];NP_078829.1//syndetin isoform b [Homo sapiens]","1//3;3//A2MP1;2//1"]
[2077,2610,202.1,161.44,-0.32407124216074,{"v":3.1824875465995e-32,"d":"3.18E-32"},"*",{"v":7.9094e-34,"d":"7.91E-34"},"ERF","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0003714//transcription corepressor activity;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0001227//transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0030154//cell differentiation;GO:0006351//transcription, DNA-templated;GO:0007049//cell cycle","K09434//ETS domain-containing transcription factor ERF","XP_018870279.1//PREDICTED: ETS domain-containing transcription factor ERF isoform X1 [Gorilla gorilla gorilla];NP_006485.2//ETS domain-containing transcription factor ERF isoform 1 [Homo sapiens];ELR46668.1//ETS domain-containing transcription factor ERF, partial [Bos mutus]","1//3;3//A2MP1"]
[3621,2562,4.93,3.94,-0.323392016921535,0.132282853414418,"*",0.065363,"ING1","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0035064//methylated histone binding","GO:0030308//negative regulation of cell growth;GO:0010941//regulation of cell death;GO:0016569//covalent chromatin modification;GO:0006606//protein import into nucleus;GO:0007049//cell cycle;GO:0045893//positive regulation of transcription, DNA-templated;GO:0008285//negative regulation of cell proliferation","K19197//inhibitor of growth protein 1","NP_001254657.1//inhibitor of growth protein 1 isoform E [Homo sapiens];NP_937862.1//inhibitor of growth protein 1 isoform A [Homo sapiens];XP_009000789.1//PREDICTED: inhibitor of growth protein 1 isoform X3 [Callithrix jacchus];NP_005528.4//inhibitor of growth protein 1 isoform D [Homo sapiens]","1//3;2//1;5"]
[171546,2538,30.23,24.17,-0.322763505862124,{"v":2.23575867152398E-5,"d":"2.24E-05"},"*",{"v":4.61036e-06,"d":"4.61E-06"},"SPTSSA","NA","NA","NA","K22069//LYR motif-containing protein 4;K12581//CCR4-NOT transcription complex subunit 7/8;K12022//tripartite motif-containing protein 46;K11447//histone demethylase [EC:1.14.11.-];K08857//NIMA (never in mitosis gene a)-related kinase 1/4/5 [EC:2.7.11.1]","XP_021793619.1//serine palmitoyltransferase small subunit A [Papio anubis]","3//A2MP1"]
[57720,6915,12.14,9.71,-0.32222522083649,{"v":4.06741396435915e-06,"d":"4.07E-06"},"*",{"v":7.43002e-07,"d":"7.43E-07"},"GPR107","GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0030136//clathrin-coated vesicle;GO:0016021//integral component of membrane;GO:0005769//early endosome","GO:0032050//clathrin heavy chain binding","GO:0072583//clathrin-dependent endocytosis","K13096//splicing factor 4;K18667//activating signal cointegrator complex subunit 2","NP_001130030.1//protein GPR107 isoform 2 [Homo sapiens];NP_001130029.1//protein GPR107 isoform 1 precursor [Homo sapiens];CAI46205.1//hypothetical protein [Homo sapiens];NP_066011.2//protein GPR107 isoform 3 [Homo sapiens]","4;1//3"]
[51290,1781,18.54,14.83,-0.3221226461709,0.00816147659826216,"*",0.00276358,"ERGIC2","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005737//cytoplasm","NA","GO:0006890//retrograde vesicle-mediated transport, Golgi to ER","K20366//endoplasmic reticulum-Golgi intermediate compartment protein 2","NP_057654.2//endoplasmic reticulum-Golgi intermediate compartment protein 2 [Homo sapiens]","2//1"]
[54084,3980,0.1,0.08,-0.321928094887363,0.833860882109332,"*",0.75629,"TSPEAR","GO:0060170//ciliary membrane;GO:0009986//cell surface;GO:0032420//stereocilium;GO:0005576//extracellular region","NA","GO:0007605//sensory perception of sound","K18263//G-protein coupled receptor 98","NP_659428.2//thrombospondin-type laminin G domain and EAR repeat-containing protein isoform 1 precursor [Homo sapiens]","1//3;2//1"]
[170575,4430,0.2,0.16,-0.321928094887363,0.889590704995288,"*",0.827218,"GIMAP1","GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0000139//Golgi membrane","GO:0005525//GTP binding","NA","K09228//KRAB domain-containing zinc finger protein;K15696//RING finger protein 113B;K17985//activating molecule in BECN1-regulated autophagy protein 1;K01064//wingless-type MMTV integration site family, member 9","NP_570115.1//GTPase IMAP family member 1 [Homo sapiens]","3//A2MP1"]
[284349,2559,1.25,1,-0.321928094887362,0.507760596402878,"*",0.353468,"ZNF283","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","NP_862828.1//zinc finger protein 283 isoform 1 [Homo sapiens];XP_016882125.1//PREDICTED: zinc finger protein 283 isoform X4 [Homo sapiens]","1//3"]
[11189,5368,0.15,0.12,-0.321928094887362,0.734202172085243,"*",0.631936,"CELF3","GO:0005634//nucleus;GO:0016604//nuclear body;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0036002//pre-mRNA binding;GO:0097322//7SK snRNA binding","GO:0006397//mRNA processing;GO:0030317//flagellated sperm motility;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0030575//nuclear body organization;GO:0007283//spermatogenesis;GO:0098781//ncRNA transcription;GO:0048026//positive regulation of mRNA splicing, via spliceosome;GO:0008380//RNA splicing","K13207//CUG-BP- and ETR3-like factor","NP_001166120.1//CUGBP Elav-like family member 3 isoform 3 [Homo sapiens];BAD92501.1//trinucleotide repeat containing 4 variant, partial [Homo sapiens];EDL38738.1//trinucleotide repeat containing 4, isoform CRA_d, partial [Mus musculus]","6;1//3;3//A2MP1"]
[3607,5262,30.06,24.06,-0.321208366740288,{"v":3.98230790626831e-10,"d":"3.98E-10"},"*",{"v":4.25554E-11,"d":"4.26E-11"},"FOXK2","GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0000287//magnesium ion binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0009653//anatomical structure morphogenesis;GO:0030154//cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0016579//protein deubiquitination","K09404//forkhead box protein K","NP_004505.2//forkhead box protein K2 [Homo sapiens]","3//A2MP1"]
[54916,4278,2.31,1.85,-0.320367580899745,0.187457918246446,"*",0.099045,"TMEM260","GO:0016021//integral component of membrane","NA","NA","NA","NP_060269.3//transmembrane protein 260 [Homo sapiens]","3//A2MP1"]
[57719,4162,4.07,3.26,-0.32015683003517,0.0679194853242321,"*",0.0298992,"ANO8","GO:0005788//endoplasmic reticulum lumen;GO:0005622//intracellular;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005229//intracellular calcium activated chloride channel activity","GO:0043687//post-translational protein modification;GO:0044267//cellular protein metabolic process;GO:0006821//chloride transport;GO:0034220//ion transmembrane transport","K19502//anoctamin-8","NP_066010.1//anoctamin-8 [Homo sapiens]","2//1"]
[64110,1700,16.51,13.23,-0.319527058634581,0.0171157214890362,"*",0.00630348,"MAGEF1","GO:0070062//extracellular exosome","NA","NA","K12464//melanoma-associated antigen D1","XP_017393867.1//PREDICTED: melanoma-associated antigen F1 [Cebus capucinus imitator]",4]
[576,5356,4.71,3.78,-0.31734082539171,0.0242514458071858,"*",0.00933834,"ADGRB2","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004930//G-protein coupled receptor activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0016525//negative regulation of angiogenesis;GO:0007422//peripheral nervous system development;GO:0007166//cell surface receptor signaling pathway;GO:0051965//positive regulation of synapse assembly","K04597//brain-specific angiogenesis inhibitor 2","NP_001281264.1//adhesion G protein-coupled receptor B2 isoform 1 preproprotein [Homo sapiens];NP_001281265.1//adhesion G protein-coupled receptor B2 isoform 2 preproprotein [Homo sapiens]","1//3"]
[4200,4630,17.97,14.43,-0.316519109018744,{"v":1.23704894394904E-5,"d":"1.24E-05"},"*",{"v":2.43166e-06,"d":"2.43E-06"},"ME2","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0008948//oxaloacetate decarboxylase activity;GO:0004473//malate dehydrogenase (decarboxylating) (NADP+) activity;GO:0004471//malate dehydrogenase (decarboxylating) (NAD+) activity;GO:0009055//electron transfer activity;GO:0046872//metal ion binding;GO:0004470//malic enzyme activity;GO:0051287//NAD binding","GO:1902031//regulation of NADP metabolic process;GO:0006090//pyruvate metabolic process;GO:0006108//malate metabolic process","K00027//malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38]","NP_002387.1//NAD-dependent malic enzyme, mitochondrial isoform 1 precursor [Homo sapiens];NP_001161807.1//NAD-dependent malic enzyme, mitochondrial isoform 2 precursor [Homo sapiens]","1//3;4"]
[2733,3339,24.09,19.35,-0.316100827206698,{"v":1.88929481257707e-05,"d":"1.89E-05"},"*",{"v":3.83678e-06,"d":"3.84E-06"},"GLE1","GO:0016020//membrane;GO:0005643//nuclear pore;GO:0031965//nuclear membrane;GO:0005615//extracellular space;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0044614//nuclear pore cytoplasmic filaments;GO:0005737//cytoplasm","GO:0042802//identical protein binding;GO:0000822//inositol hexakisphosphate binding;GO:0031369//translation initiation factor binding;GO:0005543//phospholipid binding","GO:0006449//regulation of translational termination;GO:0016973//poly(A)+ mRNA export from nucleus;GO:0006406//mRNA export from nucleus;GO:0006446//regulation of translational initiation","K18723//nucleoporin GLE1","NP_001490.1//nucleoporin GLE1 isoform 2 [Homo sapiens];NP_001003722.1//nucleoporin GLE1 isoform 1 [Homo sapiens]","1//3;2//1"]
[199223,4125,0.56,0.45,-0.31550182572793,0.579583753946465,"*",0.422914,"TTC21A","NA","NA","NA","K19673//tetratricopeptide repeat protein 21B","XP_008949787.2//PREDICTED: tetratricopeptide repeat protein 21A isoform X4 [Pan paniscus]","2//1"]
[7620,1744,1.12,0.9,-0.31550182572793,0.610822361162439,"*",0.455268,"ZNF69","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","XP_001108345.3//PREDICTED: zinc finger protein 700 [Macaca mulatta]","1//3;3//A2MP1"]
[4891,3944,16.44,13.22,-0.314488122173991,{"v":9.73024388328334e-05,"d":"9.73E-05"},"*",{"v":2.23368e-05,"d":"2.23E-05"},"SLC11A2","GO:0016020//membrane;GO:0005770//late endosome;GO:0016324//apical plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0031526//brush border membrane;GO:0005741//mitochondrial outer membrane;GO:0005737//cytoplasm;GO:0070826//paraferritin complex;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0055037//recycling endosome;GO:0005886//plasma membrane;GO:0005769//early endosome;GO:0005765//lysosomal membrane;GO:0005634//nucleus;GO:0031902//late endosome membrane;GO:0005764//lysosome;GO:0005802//trans-Golgi network;GO:1903561//extracellular vesicle;GO:0005773//vacuole;GO:0048471//perinuclear region of cytoplasm;GO:0009986//cell surface;GO:0045177//apical part of cell;GO:0045178//basal part of cell","GO:0015087//cobalt ion transmembrane transporter activity;GO:0005384//manganese ion transmembrane transporter activity;GO:0046870//cadmium ion binding;GO:0015099//nickel cation transmembrane transporter activity;GO:0005375//copper ion transmembrane transporter activity;GO:0005385//zinc ion transmembrane transporter activity;GO:0005381//iron ion transmembrane transporter activity;GO:0046915//transition metal ion transmembrane transporter activity;GO:0015094//lead ion transmembrane transporter activity;GO:0015093//ferrous iron transmembrane transporter activity;GO:0015086//cadmium ion transmembrane transporter activity;GO:0022890//inorganic cation transmembrane transporter activity;GO:0015295//solute:proton symporter activity;GO:0015078//hydrogen ion transmembrane transporter activity;GO:0015100//vanadium ion transmembrane transporter activity;GO:0005215//transporter activity","GO:0006879//cellular iron ion homeostasis;GO:0015684//ferrous iron transport;GO:0015676//vanadium ion transport;GO:0006783//heme biosynthetic process;GO:0006825//copper ion transport;GO:0048821//erythrocyte development;GO:0006824//cobalt ion transport;GO:0003032//detection of oxygen;GO:0006828//manganese ion transport;GO:0007611//learning or memory;GO:0070574//cadmium ion transmembrane transport;GO:0015675//nickel cation transport;GO:0070627//ferrous iron import;GO:0060586//multicellular organismal iron ion homeostasis;GO:0010039//response to iron ion;GO:0001666//response to hypoxia;GO:0048813//dendrite morphogenesis;GO:0034599//cellular response to oxidative stress;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0015692//lead ion transport","K21398//natural resistance-associated macrophage protein 2","XP_005268968.1//PREDICTED: natural resistance-associated macrophage protein 2 isoform X1 [Homo sapiens];NP_001167596.1//natural resistance-associated macrophage protein 2 isoform 1 [Homo sapiens];NP_001167601.1//natural resistance-associated macrophage protein 2 isoform 4 [Homo sapiens]","1//3;2//1"]
[149428,2209,3.17,2.55,-0.313985593280549,0.297907066852129,"*",0.1742982,"BNIPL","GO:0005634//nucleus;GO:0005829//cytosol","GO:0042802//identical protein binding","GO:0040009//regulation of growth rate;GO:0008285//negative regulation of cell proliferation;GO:0006915//apoptotic process","K18448//BCL2/adenovirus E1B 19 kDa protein-interacting protein 2","NP_612122.2//bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein isoform a [Homo sapiens];XP_010385529.1//PREDICTED: bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein [Rhinopithecus roxellana]","1//3;3//A2MP1"]
[2960,3033,8.59,6.91,-0.313972420750205,0.0235436923006536,"*",0.00902012,"GTF2E1","GO:0097550//transcriptional preinitiation complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005669//transcription factor TFIID complex","GO:0046872//metal ion binding;GO:0043565//sequence-specific DNA binding","GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0042795//snRNA transcription from RNA polymerase II promoter;GO:0006355//regulation of transcription, DNA-templated;GO:0016032//viral process;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter","K03136//transcription initiation factor TFIIE subunit alpha","NP_005504.2//general transcription factor IIE subunit 1 [Homo sapiens]","2//1"]
[2637,1795,3.23,2.6,-0.31302254166547,0.404355258559167,"*",0.262474,"GBX2","GO:0005634//nucleus","GO:0001190//transcriptional activator activity, RNA polymerase II transcription factor binding;GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0007399//nervous system development;GO:0021549//cerebellum development;GO:0001755//neural crest cell migration;GO:0048483//autonomic nervous system development;GO:0006355//regulation of transcription, DNA-templated;GO:0021930//cerebellar granule cell precursor proliferation;GO:0042472//inner ear morphogenesis;GO:0021794//thalamus development;GO:0021568//rhombomere 2 development;GO:0001569//branching involved in blood vessel morphogenesis;GO:0021884//forebrain neuron development;GO:0021555//midbrain-hindbrain boundary morphogenesis;GO:0007411//axon guidance","K09321//homeobox protein GBX","NP_001476.2//homeobox protein GBX-2 isoform 1 [Homo sapiens];AAC03241.1//homeobox protein [Homo sapiens]","1//3;3//A2MP1"]
[51605,2353,22.06,17.77,-0.311989109562704,0.000537993446655637,"*",0.0001424972,"TRMT6","GO:0005654//nucleoplasm;GO:0031515//tRNA (m1A) methyltransferase complex","GO:0003723//RNA binding;GO:0008168//methyltransferase activity","GO:0006400//tRNA modification;GO:0030488//tRNA methylation","K03256//tRNA (adenine-N(1)-)-methyltransferase non-catalytic subunit","NP_057023.2//tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 isoform 1 [Homo sapiens]","1//3;4"]
[284716,10583,0.36,0.29,-0.31194400631474,0.43436295463138,"*",0.28769,"RIMKLA","GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0072590//N-acetyl-L-aspartate-L-glutamate ligase activity;GO:0046872//metal ion binding;GO:0005524//ATP binding;GO:0003824//catalytic activity","GO:0008652//cellular amino acid biosynthetic process;GO:0006464//cellular protein modification process","K18311//N-acetylaspartylglutamate/N-acetylaspartylglutamylglutamate synthase [EC:6.3.2.41 6.3.2.42]","XP_007977373.1//PREDICTED: N-acetylaspartylglutamate synthase A [Chlorocebus sabaeus]","3//A2MP1"]
[9166,2495,9.09,7.33,-0.310467096060295,0.0351248694945736,"*",0.01418276,"EBAG9","NA","NA","NA","NA","XP_021544046.1//receptor-binding cancer antigen expressed on SiSo cells isoform X1 [Neomonachus schauinslandi];XP_010361399.1//PREDICTED: receptor-binding cancer antigen expressed on SiSo cells isoform X1 [Rhinopithecus roxellana];XP_017747026.1//PREDICTED: receptor-binding cancer antigen expressed on SiSo cells isoform X1 [Rhinopithecus bieti]","4;1//3;2//1"]
[79188,3343,23.51,18.97,-0.309554860241546,{"v":3.48747585245902e-05,"d":"3.49E-05"},"*",{"v":7.45788e-06,"d":"7.46E-06"},"TMEM43","GO:0005788//endoplasmic reticulum lumen;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005639//integral component of nuclear inner membrane","GO:0043621//protein self-association","GO:0071763//nuclear membrane organization","NA","NP_077310.1//transmembrane protein 43 [Homo sapiens]","2//1"]
[79157,2439,28.35,22.88,-0.309261683051202,1.11489136189706E-4,"*",{"v":2.59006e-05,"d":"2.59E-05"},"MFSD11","GO:0016021//integral component of membrane","NA","NA","K16600//tubulin polyglutamylase TTLL2 [EC:6.-.-.-];K12891//splicing factor, arginine/serine-rich 2","NP_001229465.1//UNC93-like protein MFSD11 isoform 2 [Homo sapiens];NP_077287.1//UNC93-like protein MFSD11 isoform 1 [Homo sapiens]","1//3;4;2//1"]
[51326,3994,13.3,10.74,-0.308432252403139,0.00292076770445756,"*",0.000898318,"ARL17A","GO:0005794//Golgi apparatus;GO:0005622//intracellular","GO:0005525//GTP binding","GO:0007264//small GTPase mediated signal transduction;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport","K06883//uncharacterized protein","NP_001317173.1//ADP-ribosylation factor-like 17-like isoform e [Homo sapiens];BAD92581.1//ADP-ribosylation factor 7 variant, partial [Homo sapiens];NP_001275740.1//ADP-ribosylation factor-like 17-like isoform c [Homo sapiens];NP_001096624.1//ADP-ribosylation factor-like protein 17 isoform b [Homo sapiens]","1//3;2//1"]
[84901,3877,15.42,12.46,-0.307498696891032,4.22864900120686E-4,"*",0.0001096738,"NFATC2IP","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0031386//protein tag","GO:0016925//protein sumoylation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0001816//cytokine production","K12581//CCR4-NOT transcription complex subunit 7/8;K17985//activating molecule in BECN1-regulated autophagy protein 1","NP_116204.3//NFATC2-interacting protein [Homo sapiens]","3//A2MP1"]
[161829,3114,1.2,0.97,-0.306977753421391,0.475819093328439,"*",0.32459,"EXD1","GO:0043186//P granule;GO:1990923//PET complex","GO:0003723//RNA binding;GO:0042803//protein homodimerization activity","GO:0051321//meiotic cell cycle;GO:0031047//gene silencing by RNA;GO:0034587//piRNA metabolic process","K18740//exonuclease 3'-5' domain-containing protein 1","NP_001273370.1//piRNA biogenesis protein EXD1 isoform 1 [Homo sapiens];XP_017750933.1//PREDICTED: piRNA biogenesis protein EXD1 isoform X1 [Rhinopithecus bieti]","1//3;3//A2MP1"]
[4026,17872,3.98,3.22,-0.305707742429032,{"v":4.45416244297616E-5,"d":"4.45E-05"},"*",{"v":9.70636e-06,"d":"9.71E-06"},"LPP","GO:0005634//nucleus;GO:0005925//focal adhesion;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0046872//metal ion binding","GO:0007155//cell adhesion","K16676//lipoma-prefererred partner","XP_021789580.1//lipoma-preferred partner isoform X2 [Papio anubis];XP_011511125.1//PREDICTED: lipoma-preferred partner isoform X1 [Homo sapiens];NP_001161144.1//lipoma-preferred partner isoform b [Homo sapiens]","4;2//1"]
[27297,2705,17.21,13.93,-0.305051839438951,1.75743316346564E-3,"*",0.000515546,"CRCP","GO:0005654//nucleoplasm;GO:0009360//DNA polymerase III complex;GO:0005829//cytosol;GO:0001669//acrosomal vesicle;GO:0005666//DNA-directed RNA polymerase III complex;GO:0005886//plasma membrane","GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0001635//calcitonin gene-related peptide receptor activity;GO:0000166//nucleotide binding","GO:0032481//positive regulation of type I interferon production;GO:0051607//defense response to virus;GO:0006384//transcription initiation from RNA polymerase III promoter;GO:0007218//neuropeptide signaling pathway;GO:0045087//innate immune response;GO:0006383//transcription from RNA polymerase III promoter","K01368//cathepsin S [EC:3.4.22.27];K08857//NIMA (never in mitosis gene a)-related kinase 1/4/5 [EC:2.7.11.1]","NP_001135886.1//DNA-directed RNA polymerase III subunit RPC9 isoform d [Homo sapiens];XP_011959811.1//PREDICTED: DNA-directed RNA polymerase III subunit RPC9 isoform X3 [Ovis aries];XP_009451439.1//PREDICTED: DNA-directed RNA polymerase III subunit RPC9 isoform X2 [Pan troglodytes]","4;1//3"]
[120224,1946,0.21,0.17,-0.304854581528421,0.833630724537676,"*",0.75629,"TMEM45B","GO:0016021//integral component of membrane","NA","NA","K01312//trypsin [EC:3.4.21.4]","NP_620143.1//transmembrane protein 45B [Homo sapiens]","4;1//3"]
[84317,1865,10.19,8.25,-0.304688027032636,0.0983530972885906,"*",0.0458702,"CCDC115","GO:0016020//membrane;GO:0005768//endosome;GO:0042406//extrinsic component of endoplasmic reticulum membrane;GO:0005783//endoplasmic reticulum;GO:0005764//lysosome;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0030137//COPI-coated vesicle;GO:0016471//vacuolar proton-transporting V-type ATPase complex","GO:0051082//unfolded protein binding","GO:1905146//lysosomal protein catabolic process;GO:0006879//cellular iron ion homeostasis;GO:0007042//lysosomal lumen acidification;GO:0036295//cellular response to increased oxygen levels","K22020//mucin-19;K18772//C->U-editing enzyme APOBEC2 [EC:3.5.4.-];K07297//adiponectin receptor","NP_115733.2//coiled-coil domain-containing protein 115 isoform a [Homo sapiens];NP_001308047.1//coiled-coil domain-containing protein 115 isoform b [Homo sapiens];XP_003909333.1//coiled-coil domain-containing protein 115 [Papio anubis]","1//3;3//A2MP1"]
[54861,4888,1.79,1.45,-0.303906687249322,0.243318967011456,"*",0.1369526,"SNRK","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0000287//magnesium ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding","GO:0006468//protein phosphorylation;GO:0030099//myeloid cell differentiation;GO:0035556//intracellular signal transduction","K08802//SNF related kinase [EC:2.7.11.1]","AAF86944.1//HSNFRK [Homo sapiens];CAH18415.1//hypothetical protein [Homo sapiens]","1//3;4"]
[6528,3594,2.32,1.88,-0.303392143449935,0.294597541607717,"*",0.1720668,"SLC5A5","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:1903561//extracellular vesicle","GO:0015111//iodide transmembrane transporter activity;GO:0008507//sodium:iodide symporter activity","GO:0006810//transport;GO:0015705//iodide transport;GO:0071371//cellular response to gonadotropin stimulus;GO:0006590//thyroid hormone generation;GO:0006811//ion transport;GO:0071320//cellular response to cAMP","K14385//solute carrier family 5 (sodium/iodide cotransporter), member 5","NP_000444.1//sodium/iodide cotransporter [Homo sapiens]","2//1"]
[4131,11749,23.03,18.67,-0.302792483566644,{"v":2.78529698422018e-15,"d":"2.79E-15"},"*",{"v":1.900572e-16,"d":"1.90E-16"},"MAP1B","GO:0005874//microtubule;GO:0030054//cell junction;GO:0014069//postsynaptic density;GO:0001750//photoreceptor outer segment;GO:0005875//microtubule associated complex;GO:0005829//cytosol;GO:0043197//dendritic spine;GO:0005886//plasma membrane","GO:0005198//structural molecule activity;GO:0008017//microtubule binding","GO:0007399//nervous system development;GO:0000226//microtubule cytoskeleton organization;GO:0048675//axon extension;GO:0016358//dendrite development;GO:0047497//mitochondrion transport along microtubule;GO:0061162//establishment of monopolar cell polarity;GO:0045773//positive regulation of axon extension;GO:0032387//negative regulation of intracellular transport;GO:0009987//cellular process;GO:0001578//microtubule bundle formation","K10429//microtubule-associated protein 1","NP_005900.2//microtubule-associated protein 1B isoform 1 [Homo sapiens];XP_011728513.1//PREDICTED: microtubule-associated protein 1B isoform X1 [Macaca nemestrina]","1//3;4"]
[54962,1295,11,8.92,-0.302387908491717,0.134297774545455,"*",0.0665856,"TIPIN","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031298//replication fork protection complex;GO:0000790//nuclear chromatin;GO:0005737//cytoplasm","GO:0003677//DNA binding","GO:0009411//response to UV;GO:0033262//regulation of nuclear cell cycle DNA replication;GO:0006260//DNA replication;GO:0048478//replication fork protection;GO:0000076//DNA replication checkpoint;GO:0031573//intra-S DNA damage checkpoint;GO:0044770//cell cycle phase transition;GO:0051301//cell division;GO:0043111//replication fork arrest;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle;GO:0008284//positive regulation of cell proliferation","K10904//TIMELESS-interacting protein","NP_060328.2//TIMELESS-interacting protein isoform 1 [Homo sapiens];XP_005254578.1//PREDICTED: TIMELESS-interacting protein isoform X1 [Homo sapiens]","1//3;2//1"]
[340371,3723,13.26,10.76,-0.301402697555964,1.87285401485884E-3,"*",0.000552336,"NRBP2","GO:0012505//endomembrane system;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity","GO:0030182//neuron differentiation;GO:0006468//protein phosphorylation;GO:0043524//negative regulation of neuron apoptotic process;GO:0035556//intracellular signal transduction;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0016242//negative regulation of macroautophagy","K08875//nuclear receptor-binding protein","XP_012328731.1//nuclear receptor-binding protein 2 isoform X1 [Aotus nancymaae]","3//A2MP1"]
[220134,2919,19.71,16,-0.300855871268761,0.000691210462549156,"*",0.0001870604,"SKA1","GO:0015630//microtubule cytoskeleton;GO:0005829//cytosol;GO:0000940//condensed chromosome outer kinetochore;GO:0005876//spindle microtubule","GO:0008017//microtubule binding","GO:0000278//mitotic cell cycle;GO:0007059//chromosome segregation;GO:0007062//sister chromatid cohesion;GO:0031110//regulation of microtubule polymerization or depolymerization;GO:0051301//cell division","K17985//activating molecule in BECN1-regulated autophagy protein 1","NP_659497.1//spindle and kinetochore-associated protein 1 [Homo sapiens]","3//A2MP1;2//1"]
[11004,2877,19.9,16.16,-0.300341232679216,{"v":2.90073966091612e-05,"d":"2.90E-05"},"*",{"v":6.1051e-06,"d":"6.11E-06"},"KIF2C","GO:0016020//membrane;GO:0005654//nucleoplasm;GO:0005874//microtubule;GO:0035371//microtubule plus-end;GO:0015630//microtubule cytoskeleton;GO:0005813//centrosome;GO:0000775//chromosome, centromeric region;GO:0005829//cytosol;GO:0000777//condensed chromosome kinetochore;GO:0000776//kinetochore;GO:0005871//kinesin complex","GO:0019237//centromeric DNA binding;GO:0005524//ATP binding;GO:0051010//microtubule plus-end binding;GO:0003777//microtubule motor activity;GO:0008017//microtubule binding;GO:0016887//ATPase activity","GO:0051983//regulation of chromosome segregation;GO:0000278//mitotic cell cycle;GO:0007018//microtubule-based movement;GO:0051315//attachment of mitotic spindle microtubules to kinetochore;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0007019//microtubule depolymerization;GO:0007080//mitotic metaphase plate congression;GO:0008283//cell proliferation;GO:0007062//sister chromatid cohesion;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0051301//cell division;GO:0030951//establishment or maintenance of microtubule cytoskeleton polarity;GO:0051310//metaphase plate congression","K10393//kinesin family member 2/24","NP_001284584.1//kinesin-like protein KIF2C isoform 2 [Homo sapiens];NP_001284585.1//kinesin-like protein KIF2C isoform 3 [Homo sapiens];NP_006836.2//kinesin-like protein KIF2C isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[6666,4658,58.57,47.57,-0.300109869147063,{"v":6.81460178210806E-15,"d":"6.81E-15"},"*",{"v":4.81638e-16,"d":"4.82E-16"},"SOX12","GO:0005654//nucleoplasm;GO:0032993//protein-DNA complex","GO:0001105//RNA polymerase II transcription coactivator activity;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0000976//transcription regulatory region sequence-specific DNA binding","GO:0065004//protein-DNA complex assembly;GO:0045165//cell fate commitment;GO:0021510//spinal cord development","K09268//transcription factor SOX4/11/12 (SOX group C)","XP_017370646.1//PREDICTED: transcription factor SOX-12 [Cebus capucinus imitator]","3//A2MP1"]
[55763,3514,4.43,3.6,-0.299309792225343,0.0988304993828817,"*",0.0461176,"EXOC1","GO:0016020//membrane;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0030496//midbody;GO:0000145//exocyst;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0098592//cytoplasmic side of apical plasma membrane","GO:0017049//GTP-Rho binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding","GO:0016241//regulation of macroautophagy;GO:0051601//exocyst localization;GO:0051607//defense response to virus;GO:0016032//viral process;GO:0006893//Golgi to plasma membrane transport;GO:0050714//positive regulation of protein secretion;GO:0048015//phosphatidylinositol-mediated signaling;GO:0015031//protein transport;GO:0006887//exocytosis","K19983//exocyst complex component 1","NP_060731.2//exocyst complex component 1 isoform 1 [Homo sapiens];NP_839955.1//exocyst complex component 1 isoform 2 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[23279,5197,9.62,7.82,-0.298868286462689,{"v":2.06815571583786e-07,"d":"2.07E-07"},"*",{"v":3.09822e-08,"d":"3.10E-08"},"NUP160","GO:0043657//host cell;GO:0005643//nuclear pore;GO:0005635//nuclear envelope;GO:0005829//cytosol;GO:0031080//nuclear pore outer ring","GO:0005487//nucleocytoplasmic transporter activity","GO:0006406//mRNA export from nucleus;GO:0007077//mitotic nuclear envelope disassembly;GO:0016925//protein sumoylation;GO:0060964//regulation of gene silencing by miRNA;GO:0006409//tRNA export from nucleus;GO:0016032//viral process;GO:0006110//regulation of glycolytic process;GO:1900034//regulation of cellular response to heat;GO:0007062//sister chromatid cohesion;GO:0019083//viral transcription;GO:0075733//intracellular transport of virus","K14303//nuclear pore complex protein Nup160","NP_001305328.1//nuclear pore complex protein Nup160 isoform 2 [Homo sapiens];NP_056046.1//nuclear pore complex protein Nup160 isoform 1 [Homo sapiens]","1//3;2//1"]
[23438,2509,14.58,11.86,-0.297886709780933,0.00915605149542962,"*",3.13532E-3,"HARS2","NA","NA","NA","K01892//histidyl-tRNA synthetase [EC:6.1.1.21]","XP_011795050.1//PREDICTED: probable histidine--tRNA ligase, mitochondrial isoform X4 [Colobus angolensis palliatus];XP_010386476.1//PREDICTED: probable histidine--tRNA ligase, mitochondrial isoform X3 [Rhinopithecus roxellana];XP_010342742.1//PREDICTED: probable histidine--tRNA ligase, mitochondrial isoform X2 [Saimiri boliviensis boliviensis]","1//3;3//A2MP1"]
[5792,7716,29.49,24,-0.297191416565856,{"v":2.05961826957787e-12,"d":"2.06E-12"},"*",{"v":1.771576E-13,"d":"1.77E-13"},"PTPRF","NA","NA","NA","K05695//receptor-type tyrosine-protein phosphatase F [EC:3.1.3.48]","NP_001316066.1//receptor-type tyrosine-protein phosphatase F isoform 3 precursor [Homo sapiens];NP_001316067.1//receptor-type tyrosine-protein phosphatase F isoform 4 precursor [Homo sapiens];NP_001316069.1//receptor-type tyrosine-protein phosphatase F isoform 6 precursor [Homo sapiens];XP_011934472.1//PREDICTED: receptor-type tyrosine-protein phosphatase F isoform X8 [Cercocebus atys];NP_001316068.1//receptor-type tyrosine-protein phosphatase F isoform 5 precursor [Homo sapiens];XP_011934473.1//PREDICTED: receptor-type tyrosine-protein phosphatase F isoform X9 [Cercocebus atys]","4;1//3;3//A2MP1"]
[3416,5513,12.16,9.9,-0.296642798476613,{"v":1.38496353373185e-07,"d":"1.38E-07"},"*",{"v":2.03054e-08,"d":"2.03E-08"},"IDE","GO:0005634//nucleus;GO:0005615//extracellular space;GO:0005782//peroxisomal matrix;GO:0031597//cytosolic proteasome complex;GO:0005777//peroxisome;GO:0005737//cytoplasm;GO:0009986//cell surface;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005886//plasma membrane","GO:0031626//beta-endorphin binding;GO:0001540//amyloid-beta binding;GO:0004222//metalloendopeptidase activity;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0005102//receptor binding;GO:0042277//peptide binding;GO:0042803//protein homodimerization activity;GO:0043559//insulin binding;GO:0140036//ubiquitin-dependent protein binding;GO:0008270//zinc ion binding;GO:0001618//virus receptor activity;GO:0016887//ATPase activity","GO:1901143//insulin catabolic process;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0045861//negative regulation of proteolysis;GO:0008286//insulin receptor signaling pathway;GO:0097242//amyloid-beta clearance;GO:0051260//protein homooligomerization;GO:0050435//amyloid-beta metabolic process;GO:0042447//hormone catabolic process;GO:1901142//insulin metabolic process;GO:0010815//bradykinin catabolic process;GO:0051291//protein heterooligomerization;GO:0051289//protein homotetramerization;GO:0032461//positive regulation of protein oligomerization;GO:0008340//determination of adult lifespan;GO:0006508//proteolysis;GO:0045732//positive regulation of protein catabolic process;GO:0010992//ubiquitin recycling","K01408//insulysin [EC:3.4.24.56]","XP_014387048.1//PREDICTED: insulin-degrading enzyme isoform X1 [Myotis brandtii];XP_016774359.1//PREDICTED: insulin-degrading enzyme isoform X4 [Pan troglodytes];XP_003922440.2//PREDICTED: insulin-degrading enzyme isoform X1 [Saimiri boliviensis boliviensis];XP_016871679.1//PREDICTED: insulin-degrading enzyme isoform X2 [Homo sapiens];NP_001309723.1//insulin-degrading enzyme isoform 4 [Homo sapiens];NP_004960.2//insulin-degrading enzyme isoform 1 [Homo sapiens];NP_001309722.1//insulin-degrading enzyme isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[2776,6343,7.43,6.05,-0.296427068376639,0.00272052277459016,"*",0.00083111,"GNAQ","GO:0016020//membrane;GO:0005765//lysosomal membrane;GO:0070062//extracellular exosome;GO:0030425//dendrite;GO:0031965//nuclear membrane;GO:0005834//heterotrimeric G-protein complex;GO:0001750//photoreceptor outer segment;GO:0044297//cell body;GO:0005901//caveola;GO:0043234//protein complex;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0003924//GTPase activity;GO:0031683//G-protein beta/gamma-subunit complex binding;GO:0046872//metal ion binding;GO:0001664//G-protein coupled receptor binding;GO:0031826//type 2A serotonin receptor binding;GO:0047391//alkylglycerophosphoethanolamine phosphodiesterase activity;GO:0005525//GTP binding;GO:0004871//signal transducer activity;GO:0005096//GTPase activator activity;GO:0032403//protein complex binding","GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0043267//negative regulation of potassium ion transport;GO:0050796//regulation of insulin secretion;GO:0042733//embryonic digit morphogenesis;GO:0045634//regulation of melanocyte differentiation;GO:0043065//positive regulation of apoptotic process;GO:0048066//developmental pigmentation;GO:0009791//post-embryonic development;GO:0070208//protein heterotrimerization;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0021884//forebrain neuron development;GO:0007215//glutamate receptor signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007213//G-protein coupled acetylcholine receptor signaling pathway;GO:0035412//regulation of catenin import into nucleus;GO:0007507//heart development;GO:0009649//entrainment of circadian clock;GO:0043066//negative regulation of apoptotic process;GO:0060158//phospholipase C-activating dopamine receptor signaling pathway;GO:0006469//negative regulation of protein kinase activity;GO:0007603//phototransduction, visible light;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0007202//activation of phospholipase C activity;GO:0001508//action potential;GO:0001501//skeletal system development;GO:0050821//protein stabilization;GO:0042711//maternal behavior;GO:0016322//neuron remodeling","K04634//guanine nucleotide-binding protein G(q) subunit alpha","XP_020040613.1//guanine nucleotide-binding protein G(q) subunit alpha [Castor canadensis]",4]
[8569,2680,8.69,7.08,-0.295606816731403,0.0793865442176871,"*",0.035797,"MKNK1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004683//calmodulin-dependent protein kinase activity;GO:0009931//calcium-dependent protein serine/threonine kinase activity;GO:0005516//calmodulin binding","GO:0018105//peptidyl-serine phosphorylation;GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction;GO:0006417//regulation of translation;GO:0046777//protein autophosphorylation","K04372//MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]","NP_003675.2//MAP kinase-interacting serine/threonine-protein kinase 1 isoform 1 [Homo sapiens];XP_018873451.1//PREDICTED: MAP kinase-interacting serine/threonine-protein kinase 1 isoform X2 [Gorilla gorilla gorilla];XP_018873478.1//PREDICTED: MAP kinase-interacting serine/threonine-protein kinase 1 isoform X6 [Gorilla gorilla gorilla]","3//A2MP1;2//1;5"]
[22889,3009,13.02,10.61,-0.295304792250871,0.00759766164276402,"*",0.00255364,"KHDC4","GO:0005634//nucleus;GO:0005681//spliceosomal complex;GO:0030529//intracellular ribonucleoprotein complex;GO:0019013//viral nucleocapsid;GO:0005737//cytoplasm","GO:0003723//RNA binding","GO:0006376//mRNA splice site selection","K13095//splicing factor 1;K16882//protein piccolo","NP_055764.2//UPF0469 protein KIAA0907 [Homo sapiens]","3//A2MP1"]
[908,2681,108.56,88.5,-0.294743265561132,{"v":3.59406318478261e-15,"d":"3.59E-15"},"*",{"v":2.48394E-16,"d":"2.48E-16"},"CCT6A","GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0005874//microtubule;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005832//chaperonin-containing T-complex","GO:0003723//RNA binding;GO:0005524//ATP binding;GO:0071987//WD40-repeat domain binding;GO:0051082//unfolded protein binding;GO:0044183//protein binding involved in protein folding","GO:0006457//protein folding;GO:1904874//positive regulation of telomerase RNA localization to Cajal body;GO:1904851//positive regulation of establishment of protein localization to telomere;GO:1904871//positive regulation of protein localization to Cajal body;GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0006458//'de novo' protein folding;GO:0050821//protein stabilization;GO:0061077//chaperone-mediated protein folding","K09498//T-complex protein 1 subunit zeta","NP_001009186.1//T-complex protein 1 subunit zeta isoform b [Homo sapiens];XP_012304540.1//T-complex protein 1 subunit zeta [Aotus nancymaae]","1//3;3//A2MP1"]
[153090,5196,11.17,9.11,-0.294106226681264,0.00276713601963993,"*",0.000846736,"DAB2IP","GO:0044301//climbing fiber;GO:0030424//axon;GO:0044300//cerebellar mossy fiber;GO:1990597//AIP1-IRE1 complex","GO:0071889//14-3-3 protein binding;GO:0005123//death receptor binding;GO:0005096//GTPase activator activity;GO:0045296//cadherin binding","GO:0001525//angiogenesis;GO:0016525//negative regulation of angiogenesis;GO:0007257//activation of JUN kinase activity;GO:0000185//activation of MAPKKK activity;GO:0043065//positive regulation of apoptotic process;GO:0030948//negative regulation of vascular endothelial growth factor receptor signaling pathway;GO:0038026//reelin-mediated signaling pathway;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0008285//negative regulation of cell proliferation","K19901//disabled homolog 2-interacting protein","NP_115941.2//disabled homolog 2-interacting protein isoform 1 [Homo sapiens];XP_016817061.1//PREDICTED: disabled homolog 2-interacting protein isoform X2 [Pan troglodytes]","3//A2MP1;2//1"]
[54969,1233,15.41,12.57,-0.293882212094278,0.0846298693102024,"*",0.0384792,"HPF1","GO:0005634//nucleus","GO:0042393//histone binding","GO:0018312//peptidyl-serine ADP-ribosylation;GO:0010835//regulation of protein ADP-ribosylation;GO:0006974//cellular response to DNA damage stimulus","K10380//ankyrin","NP_060337.2//histone PARylation factor 1 [Homo sapiens]","2//1"]
[842,2720,3.75,3.06,-0.293358942690591,0.328563065232825,"*",0.1970062,"CASP9","GO:0005634//nucleus;GO:0043293//apoptosome;GO:0043234//protein complex;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005737//cytoplasm","GO:0008233//peptidase activity;GO:0042802//identical protein binding;GO:0004197//cysteine-type endopeptidase activity;GO:0017124//SH3 domain binding;GO:0008047//enzyme activator activity;GO:0019901//protein kinase binding;GO:0097200//cysteine-type endopeptidase activity involved in execution phase of apoptosis","GO:0034349//glial cell apoptotic process;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0032496//response to lipopolysaccharide;GO:2001020//regulation of response to DNA damage stimulus;GO:0046677//response to antibiotic;GO:0034644//cellular response to UV;GO:0043065//positive regulation of apoptotic process;GO:0032355//response to estradiol;GO:0030220//platelet formation;GO:0006974//cellular response to DNA damage stimulus;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0043525//positive regulation of neuron apoptotic process;GO:0007568//aging;GO:0006915//apoptotic process;GO:0071549//cellular response to dexamethasone stimulus;GO:0032025//response to cobalt ion;GO:0042770//signal transduction in response to DNA damage;GO:0097194//execution phase of apoptosis;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0008635//activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c","K04399//caspase 9 [EC:3.4.22.62]","BAD92384.1//caspase 9 isoform alpha preproprotein variant, partial [Homo sapiens];NP_001220.2//caspase-9 isoform alpha precursor [Homo sapiens];NP_001264983.1//caspase-9 isoform beta [Homo sapiens]","1//3;4;3//A2MP1"]
[11279,8397,0.49,0.4,-0.292781749227846,0.446172816753927,"*",0.298752,"KLF8","GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016235//aggresome","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated","K09205//krueppel-like factor 8/12","XP_016798882.1//PREDICTED: Krueppel-like factor 8 isoform X1 [Pan troglodytes];NP_001311028.1//Krueppel-like factor 8 isoform 3 [Homo sapiens];NP_001311029.1//Krueppel-like factor 8 isoform 4 [Homo sapiens];XP_008957781.1//PREDICTED: Krueppel-like factor 8 isoform X1 [Pan paniscus];XP_016798883.1//PREDICTED: Krueppel-like factor 8 isoform X2 [Pan troglodytes]","1//3;2//1;5"]
[90843,1164,20.76,16.95,-0.292521170334175,0.0444193252476734,"*",0.0185252,"TCEAL8","GO:0005634//nucleus","GO:0050699//WW domain binding;GO:0003746//translation elongation factor activity","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated","NA","NP_699164.1//transcription elongation factor A protein-like 8 [Homo sapiens]","1//3;2//1"]
[26225,3102,13,10.62,-0.291727857111663,0.00904100944231121,"*",0.00309536,"ARL5A","GO:0005622//intracellular","GO:0005525//GTP binding","GO:1903292//protein localization to Golgi membrane;GO:0007264//small GTPase mediated signal transduction","K07949//ADP-ribosylation factor-like protein 5A","XP_004842625.1//ADP-ribosylation factor-like protein 5A [Heterocephalus glaber];EDL26907.1//ADP-ribosylation factor-like 5A, partial [Mus musculus];NP_036229.1//ADP-ribosylation factor-like protein 5A isoform 1 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[1810,3222,11.21,9.16,-0.291366774708483,0.0119214902980837,"*",0.00420618,"DR1","GO:0005634//nucleus;GO:0005671//Ada2/Gcn5/Ada3 transcription activator complex","GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0017025//TBP-class protein binding;GO:0046982//protein heterodimerization activity;GO:0008134//transcription factor binding","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0043966//histone H3 acetylation;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K21751//down-regulator of transcription 1","XP_011746186.1//PREDICTED: uncharacterized protein LOC105485493 [Macaca nemestrina]","2//1"]
[64225,4035,21.07,17.22,-0.291105171420462,{"v":4.78970913898305e-06,"d":"4.79E-06"},"*",{"v":8.8454E-7,"d":"8.85E-07"},"ATL2","GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0098826//endoplasmic reticulum tubular network membrane","GO:0042802//identical protein binding;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:1990809//endoplasmic reticulum tubular network membrane organization;GO:0051260//protein homooligomerization;GO:0007030//Golgi organization;GO:0007029//endoplasmic reticulum organization","K17339//atlastin [EC:3.6.5.-]","NP_001317392.1//atlastin-2 isoform 8 [Homo sapiens];NP_001317391.1//atlastin-2 isoform 7 [Homo sapiens];NP_001317388.1//atlastin-2 isoform 5 [Homo sapiens];NP_071769.2//atlastin-2 isoform 1 [Homo sapiens];XP_012330934.1//atlastin-2 isoform X1 [Aotus nancymaae];XP_012509310.1//PREDICTED: atlastin-2 isoform X1 [Propithecus coquereli];XP_012330936.1//atlastin-2 isoform X3 [Aotus nancymaae];NP_001129145.1//atlastin-2 isoform 2 [Homo sapiens];NP_001295005.1//atlastin-2 isoform 3 [Homo sapiens]","4;1//3;3//A2MP1"]
[51001,1470,18.46,15.1,-0.289854003433333,0.0355407288256228,"*",0.0143796,"MTERF3","GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane","GO:0044212//transcription regulatory region DNA binding;GO:0003690//double-stranded DNA binding;GO:0003727//single-stranded RNA binding;GO:0019843//rRNA binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0032502//developmental process;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0008380//RNA splicing;GO:0042255//ribosome assembly;GO:0016236//macroautophagy","K15032//mTERF domain-containing protein, mitochondrial","NP_001273572.1//transcription termination factor 3, mitochondrial isoform 2 precursor [Homo sapiens];NP_057026.3//transcription termination factor 3, mitochondrial isoform 1 precursor [Homo sapiens]","1//3;4"]
[202,7562,0.33,0.27,-0.289506617194985,0.587483076739427,"*",0.431326,"CRYBG1","NA","NA","NA","K04257//olfactory receptor;K16810//TBCC domain-containing protein 1","XP_005266896.1//PREDICTED: absent in melanoma 1 protein isoform X1 [Homo sapiens]","3//A2MP1"]
[145447,1477,0.33,0.27,-0.289506617194985,0.66970232336605,"*",0.551014,"ABHD12B","NA","GO:0016787//hydrolase activity","NA","K13705//abhydrolase domain-containing protein 12B","XP_007984854.1//PREDICTED: abhydrolase domain-containing protein 12B isoform X2 [Chlorocebus sabaeus];NP_001193602.1//protein ABHD12B isoform a [Homo sapiens];NP_861535.1//protein ABHD12B isoform c [Homo sapiens]","1//3;3//A2MP1"]
[51808,3641,12.73,10.42,-0.28887714162285,0.00397847085182987,"*",1.258994E-3,"PHAX","NA","NA","NA","K14291//phosphorylated adapter RNA export protein","EAW48850.1//RNA U, small nuclear RNA export adaptor (phosphorylation regulated), partial [Homo sapiens]","3//A2MP1"]
[6804,2138,36.14,29.61,-0.287512015687046,0.000160684259425587,"*",{"v":3.85264e-05,"d":"3.85E-05"},"STX1A","GO:0030054//cell junction;GO:0048787//presynaptic active zone membrane;GO:0070044//synaptobrevin 2-SNAP-25-syntaxin-1a complex;GO:0005887//integral component of plasma membrane;GO:0030672//synaptic vesicle membrane;GO:0005829//cytosol;GO:0005576//extracellular region;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0030424//axon;GO:0031965//nuclear membrane;GO:0008021//synaptic vesicle;GO:0014069//postsynaptic density;GO:0043005//neuron projection;GO:0070032//synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex;GO:0030141//secretory granule;GO:0042641//actomyosin;GO:0031201//SNARE complex;GO:0070033//synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex","GO:0000149//SNARE binding;GO:0005484//SNAP receptor activity;GO:0019855//calcium channel inhibitor activity;GO:0047485//protein N-terminus binding;GO:0030674//protein binding, bridging;GO:0046982//protein heterodimerization activity;GO:0043008//ATP-dependent protein binding;GO:0044325//ion channel binding;GO:0019904//protein domain specific binding;GO:0019869//chloride channel inhibitor activity;GO:0019900//kinase binding;GO:0017022//myosin binding;GO:0048306//calcium-dependent protein binding;GO:0032028//myosin head/neck binding","GO:0010701//positive regulation of norepinephrine secretion;GO:0072657//protein localization to membrane;GO:0009629//response to gravity;GO:0050796//regulation of insulin secretion;GO:0007269//neurotransmitter secretion;GO:0001956//positive regulation of neurotransmitter secretion;GO:0010807//regulation of synaptic vesicle priming;GO:0048278//vesicle docking;GO:0035493//SNARE complex assembly;GO:0031629//synaptic vesicle fusion to presynaptic active zone membrane;GO:0045956//positive regulation of calcium ion-dependent exocytosis;GO:0032940//secretion by cell;GO:0033605//positive regulation of catecholamine secretion;GO:2000463//positive regulation of excitatory postsynaptic potential;GO:0006886//intracellular protein transport;GO:0016081//synaptic vesicle docking;GO:0014047//glutamate secretion","K04560//syntaxin 1A","NP_001159375.1//syntaxin-1A isoform 2 [Homo sapiens];XP_002743976.1//PREDICTED: syntaxin-1A isoform X1 [Callithrix jacchus]","1//3;3//A2MP1"]
[23355,5052,3.49,2.86,-0.287211889431263,0.0847734726321586,"*",0.0385498,"VPS8","GO:0005769//early endosome;GO:0033263//CORVET complex","GO:0046872//metal ion binding","GO:0034058//endosomal vesicle fusion;GO:0015031//protein transport","K20178//vacuolar protein sorting-associated protein 8","NP_056118.2//vacuolar protein sorting-associated protein 8 homolog isoform b [Homo sapiens];NP_001336225.1//vacuolar protein sorting-associated protein 8 homolog isoform c [Homo sapiens];NP_001009921.1//vacuolar protein sorting-associated protein 8 homolog isoform a [Homo sapiens];XP_016015197.1//PREDICTED: vacuolar protein sorting-associated protein 8 homolog isoform X4 [Rousettus aegyptiacus]","1//3;3//A2MP1;2//1"]
[5213,3443,17.64,14.46,-0.286783008606403,1.447380894383E-3,"*",0.000417796,"PFKM","GO:0070062//extracellular exosome;GO:0016324//apical plasma membrane;GO:0005829//cytosol;GO:0097228//sperm principal piece;GO:0005945//6-phosphofructokinase complex;GO:0005737//cytoplasm","GO:0070061//fructose binding;GO:0046872//metal ion binding;GO:0003872//6-phosphofructokinase activity;GO:0008022//protein C-terminus binding;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0019900//kinase binding;GO:0042803//protein homodimerization activity","GO:0061621//canonical glycolysis;GO:0032024//positive regulation of insulin secretion;GO:0005980//glycogen catabolic process;GO:0093001//glycolysis from storage polysaccharide through glucose-1-phosphate;GO:0006096//glycolytic process;GO:0046716//muscle cell cellular homeostasis;GO:0042593//glucose homeostasis;GO:0006002//fructose 6-phosphate metabolic process;GO:0051259//protein oligomerization","K00850//6-phosphofructokinase 1 [EC:2.7.1.11]","NP_001341664.1//ATP-dependent 6-phosphofructokinase, muscle type isoform 3 [Homo sapiens];NP_001341675.1//ATP-dependent 6-phosphofructokinase, muscle type isoform 7 [Homo sapiens];NP_001160158.1//ATP-dependent 6-phosphofructokinase, muscle type isoform 1 [Homo sapiens];XP_016779021.1//PREDICTED: ATP-dependent 6-phosphofructokinase, muscle type isoform X4 [Pan troglodytes];NP_001341669.1//ATP-dependent 6-phosphofructokinase, muscle type isoform 4 [Homo sapiens];NP_001341676.1//ATP-dependent 6-phosphofructokinase, muscle type isoform 8 [Homo sapiens]","1//3;5"]
[1977,10386,7.34,6.02,-0.286016576083511,1.22317398929336E-4,"*",{"v":2.86076E-5,"d":"2.86E-05"},"EIF4E","GO:0070062//extracellular exosome;GO:0010494//cytoplasmic stress granule;GO:0000932//P-body;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0005845//mRNA cap binding complex;GO:0033391//chromatoid body;GO:0005829//cytosol;GO:0016442//RISC complex;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0016281//eukaryotic translation initiation factor 4F complex","GO:0003743//translation initiation factor activity;GO:0003723//RNA binding;GO:0000339//RNA cap binding;GO:0000340//RNA 7-methylguanosine cap binding;GO:0070491//repressing transcription factor binding;GO:0019899//enzyme binding;GO:0031370//eukaryotic initiation factor 4G binding","GO:0006406//mRNA export from nucleus;GO:0030324//lung development;GO:0045931//positive regulation of mitotic cell cycle;GO:0016032//viral process;GO:0006417//regulation of translation;GO:0006405//RNA export from nucleus;GO:0071549//cellular response to dexamethasone stimulus;GO:0001662//behavioral fear response;GO:0006413//translational initiation;GO:0045665//negative regulation of neuron differentiation;GO:0019827//stem cell population maintenance;GO:0017148//negative regulation of translation;GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0000082//G1/S transition of mitotic cell cycle","K03259//translation initiation factor 4E","NP_001124151.1//eukaryotic translation initiation factor 4E isoform 2 [Homo sapiens];NP_001317946.1//eukaryotic translation initiation factor 4E isoform 4 [Homo sapiens];XP_005964407.1//PREDICTED: eukaryotic translation initiation factor 4E [Pantholops hodgsonii];NP_001124150.1//eukaryotic translation initiation factor 4E isoform 3 [Homo sapiens]","1//3;4;2//1"]
[80196,1982,17.69,14.51,-0.285886528623714,0.00258539173542139,"*",0.000785458,"RNF34","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016607//nuclear speck;GO:0005737//cytoplasm;GO:0012505//endomembrane system;GO:0005829//cytosol;GO:0016604//nuclear body;GO:0005886//plasma membrane","GO:0061630//ubiquitin protein ligase activity;GO:1901981//phosphatidylinositol phosphate binding;GO:0046872//metal ion binding;GO:0002039//p53 binding;GO:0031625//ubiquitin protein ligase binding;GO:0016874//ligase activity","GO:0070936//protein K48-linked ubiquitination;GO:1901797//negative regulation of signal transduction by p53 class mediator;GO:2000374//regulation of oxygen metabolic process;GO:0016567//protein ubiquitination;GO:0070417//cellular response to cold;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0006915//apoptotic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:2001271//negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis","K20804//E3 ubiquitin-protein ligase RNF34 [EC:2.3.2.27]","XP_021569924.1//E3 ubiquitin-protein ligase RNF34 isoform X3 [Carlito syrichta];NP_919247.1//E3 ubiquitin-protein ligase RNF34 isoform 1 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[10664,3665,20.54,16.86,-0.284831645376113,{"v":8.75004488645418e-09,"d":"8.75E-09"},"*",{"v":1.099918E-9,"d":"1.10E-09"},"CTCF","GO:0000793//condensed chromosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0000775//chromosome, centromeric region","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003714//transcription corepressor activity;GO:0043035//chromatin insulator sequence binding;GO:0044212//transcription regulatory region DNA binding;GO:0003676//nucleic acid binding;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0008270//zinc ion binding;GO:0003700//DNA binding transcription factor activity","GO:0045892//negative regulation of transcription, DNA-templated;GO:0010216//maintenance of DNA methylation;GO:0040029//regulation of gene expression, epigenetic;GO:0035065//regulation of histone acetylation;GO:0071459//protein localization to chromosome, centromeric region;GO:0007059//chromosome segregation;GO:0006349//regulation of gene expression by genetic imprinting;GO:0070602//regulation of centromeric sister chromatid cohesion;GO:0010628//positive regulation of gene expression;GO:0006306//DNA methylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0016584//nucleosome positioning;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0031060//regulation of histone methylation;GO:0016569//covalent chromatin modification;GO:0040030//regulation of molecular function, epigenetic","K09228//KRAB domain-containing zinc finger protein","XP_013969561.1//transcriptional repressor CTCF isoform X1 [Canis lupus familiaris];NP_006556.1//transcriptional repressor CTCF isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[54069,1587,13.95,11.46,-0.283658077959645,0.0679666103796389,"*",0.0299242,"MIS18A","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0000785//chromatin;GO:0000775//chromosome, centromeric region","GO:0046872//metal ion binding","GO:0007059//chromosome segregation;GO:1903955//positive regulation of protein targeting to mitochondrion;GO:0051301//cell division;GO:0044030//regulation of DNA methylation;GO:0034080//CENP-A containing nucleosome assembly;GO:0007049//cell cycle","K11564//kinetochore protein Mis18","NP_061817.1//protein Mis18-alpha [Homo sapiens]","2//1"]
[1459,1719,15.24,12.52,-0.283628340560704,0.0438923274710744,"*",0.01828618,"CSNK2A2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031519//PcG protein complex;GO:0005829//cytosol;GO:0000785//chromatin;GO:0001669//acrosomal vesicle;GO:0005886//plasma membrane","GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0047485//protein N-terminus binding","GO:0006457//protein folding;GO:0097421//liver regeneration;GO:0006355//regulation of transcription, DNA-templated;GO:1903955//positive regulation of protein targeting to mitochondrion;GO:0006351//transcription, DNA-templated;GO:1905818//regulation of chromosome separation;GO:1903146//regulation of autophagy of mitochondrion;GO:0007283//spermatogenesis;GO:0006915//apoptotic process;GO:1901796//regulation of signal transduction by p53 class mediator;GO:0021987//cerebral cortex development;GO:0016055//Wnt signaling pathway;GO:0007049//cell cycle;GO:0006656//phosphatidylcholine biosynthetic process;GO:0016236//macroautophagy","K03097//casein kinase II subunit alpha [EC:2.7.11.1]","NP_001887.1//casein kinase II subunit alpha' [Homo sapiens]","3//A2MP1"]
[57167,4006,1.18,0.97,-0.282730207174714,0.311458955391433,"*",0.1848008,"SALL4","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0043234//protein complex;GO:0000792//heterochromatin;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0043565//sequence-specific DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0008134//transcription factor binding;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0007165//signal transduction;GO:0006355//regulation of transcription, DNA-templated;GO:0035019//somatic stem cell population maintenance;GO:0030326//embryonic limb morphogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0022008//neurogenesis;GO:0001833//inner cell mass cell proliferation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0001843//neural tube closure;GO:0003281//ventricular septum development","K19871//sal-like protein","NP_001304960.1//sal-like protein 4 isoform 2 [Homo sapiens];NP_065169.1//sal-like protein 4 isoform 1 [Homo sapiens]","4;1//3"]
[56648,5537,4.4,3.62,-0.281513826441454,0.0507275235875498,"*",0.0215276,"EIF5A2","NA","NA","NA","K03263//translation initiation factor 5A","ELK13603.1//Eukaryotic translation initiation factor 5A-2 [Pteropus alecto]",5]
[8629,9124,3.73,3.07,-0.280936974885058,1.45199628706625E-4,"*",{"v":3.45774e-05,"d":"3.46E-05"},"JRK","GO:0005634//nucleus;GO:0030529//intracellular ribonucleoprotein complex;GO:0005737//cytoplasm","GO:0003729//mRNA binding;GO:0003677//DNA binding","NA","K09228//KRAB domain-containing zinc finger protein;K09229//KRAB and SCAN domains-containing zinc finger protein;K19326//nesprin-1;K05164//interleukin 17 receptor A","NP_003715.3//jerky protein homolog isoform a [Homo sapiens];NP_001070995.2//jerky protein homolog isoform b [Homo sapiens]","1//3;3//A2MP1;2//1"]
[6288,579,0.51,0.42,-0.280107919192735,0.782763473661762,"*",0.689316,"SAA1","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0034364//high-density lipoprotein particle;GO:0005881//cytoplasmic microtubule;GO:0005576//extracellular region;GO:0071682//endocytic vesicle lumen","GO:0001664//G-protein coupled receptor binding;GO:0008201//heparin binding;GO:0042056//chemoattractant activity","GO:0048247//lymphocyte chemotaxis;GO:0030593//neutrophil chemotaxis;GO:0000187//activation of MAPK activity;GO:0045785//positive regulation of cell adhesion;GO:0006953//acute-phase response;GO:0030168//platelet activation;GO:0050716//positive regulation of interleukin-1 secretion;GO:0050728//negative regulation of inflammatory response;GO:0044267//cellular protein metabolic process;GO:0006898//receptor-mediated endocytosis;GO:0050708//regulation of protein secretion;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0048246//macrophage chemotaxis;GO:0050715//positive regulation of cytokine secretion;GO:0045087//innate immune response","K17310//serum amyloid A protein","XP_002822026.1//PREDICTED: serum amyloid A-1 protein [Pongo abelii];NP_954630.1//serum amyloid A-1 protein preproprotein [Homo sapiens]","4;2//1;5"]
[1054,3725,17.7,14.58,-0.279758640643423,1.01911339433162E-3,"*",0.00028588,"CEBPG","NA","NA","NA","K10049//CCAAT/enhancer binding protein (C/EBP), gamma","XP_012303880.1//CCAAT/enhancer-binding protein gamma isoform X1 [Aotus nancymaae];XP_004999640.1//PREDICTED: LOW QUALITY PROTEIN: CCAAT/enhancer-binding protein gamma-like [Cavia porcellus]","1//3;3//A2MP1"]
[28231,2796,7.27,5.99,-0.279399361130809,0.085360582841455,"*",0.038929,"SLCO4A1","NA","NA","NA","K14354//solute carrier organic anion transporter family, member 4A","XP_003904570.1//solute carrier organic anion transporter family member 4A1 [Papio anubis]","3//A2MP1"]
[79627,8875,3.64,3,-0.278975949702815,0.0238781969577281,"*",0.00915874,"OGFRL1","GO:0016020//membrane","GO:0004872//receptor activity","NA","K06245//laminin, beta 4;K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K01064//wingless-type MMTV integration site family, member 9;K12025//tripartite motif-containing protein 52","NP_078852.3//opioid growth factor receptor-like protein 1 isoform b [Homo sapiens];NP_001311195.1//opioid growth factor receptor-like protein 1 isoform a [Homo sapiens]","1//3;4"]
[4298,4530,22.25,18.35,-0.278025273010547,{"v":2.22895528432564E-5,"d":"2.23E-05"},"*",{"v":4.59354e-06,"d":"4.59E-06"},"MLLT1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0008023//transcription elongation factor complex;GO:0005829//cytosol;GO:0001650//fibrillar center","GO:0003677//DNA binding","GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0006469//negative regulation of protein kinase activity;GO:0006355//regulation of transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter","K15187//YEATS domain-containing protein 1/3","NP_005925.2//protein ENL [Homo sapiens]","3//A2MP1"]
[29109,3865,23.68,19.53,-0.277977131742158,{"v":5.87682738826185e-05,"d":"5.88E-05"},"*",{"v":1.303836e-05,"d":"1.30E-05"},"FHOD1","GO:0016020//membrane;GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0001725//stress fiber;GO:0032059//bleb;GO:0005829//cytosol;GO:0014704//intercalated disc","GO:0003779//actin binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0043621//protein self-association","GO:0051496//positive regulation of stress fiber assembly;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0051660//establishment of centrosome localization;GO:0051492//regulation of stress fiber assembly;GO:0007097//nuclear migration","K05740//diaphanous 1;K05741//diaphanous 2","NP_001305131.1//FH1/FH2 domain-containing protein 1 isoform 1 [Homo sapiens];NP_037373.2//FH1/FH2 domain-containing protein 1 isoform 2 [Homo sapiens]","1//3;2//1"]
[5780,3963,21.47,17.73,-0.276129654960085,0.000122351951310861,"*",{"v":2.8631e-05,"d":"2.86E-05"},"PTPN9","GO:0005737//cytoplasm","GO:0004726//non-membrane spanning protein tyrosine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity","GO:0006470//protein dephosphorylation","K18038//tyrosine-protein phosphatase non-receptor type 9 [EC:3.1.3.48]","XP_003901277.2//tyrosine-protein phosphatase non-receptor type 9 [Papio anubis]","3//A2MP1"]
[1592,2119,0.23,0.19,-0.275634442613427,0.849755121790922,"*",0.777036,"CYP26A1","GO:0031090//organelle membrane;GO:0005789//endoplasmic reticulum membrane","GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen;GO:0020037//heme binding;GO:0008401//retinoic acid 4-hydroxylase activity;GO:0005506//iron ion binding;GO:0004497//monooxygenase activity;GO:0001972//retinoic acid binding;GO:0019825//oxygen binding","GO:0042573//retinoic acid metabolic process;GO:0006766//vitamin metabolic process;GO:0034653//retinoic acid catabolic process;GO:0048387//negative regulation of retinoic acid receptor signaling pathway;GO:0006805//xenobiotic metabolic process;GO:0016125//sterol metabolic process","K07437//cytochrome P450 family 26 subfamily A","NP_000774.2//cytochrome P450 26A1 isoform 1 [Homo sapiens]","3//A2MP1;2//1"]
[59283,8751,3.92,3.24,-0.274859841230583,0.0201917534555148,"*",0.00758676,"CACNG8","NA","NA","NA","K04873//voltage-dependent calcium channel gamma-8","XP_012355367.1//PREDICTED: voltage-dependent calcium channel gamma-8 subunit [Nomascus leucogenys]",5]
[10283,2073,8.09,6.69,-0.274133491788517,0.118450537916667,"*",0.0569488,"CWC27","GO:0005654//nucleoplasm;GO:0071013//catalytic step 2 spliceosome","GO:0003755//peptidyl-prolyl cis-trans isomerase activity","GO:0006457//protein folding;GO:0000398//mRNA splicing, via spliceosome","K12737//peptidyl-prolyl cis-trans isomerase SDCCAG10 [EC:5.2.1.8]","NP_001284574.1//peptidyl-prolyl cis-trans isomerase CWC27 homolog isoform 3 [Homo sapiens];NP_005860.2//peptidyl-prolyl cis-trans isomerase CWC27 homolog isoform 1 [Homo sapiens];NP_001284573.1//peptidyl-prolyl cis-trans isomerase CWC27 homolog isoform 2 [Homo sapiens];NP_001304929.1//peptidyl-prolyl cis-trans isomerase CWC27 homolog isoform 4 [Homo sapiens]","1//3;3//A2MP1"]
[84128,2716,26.84,22.2,-0.273824994962715,0.000491202022783603,"*",0.0001290274,"WDR75","GO:0005654//nucleoplasm;GO:0005730//nucleolus","GO:0003723//RNA binding","GO:1903955//positive regulation of protein targeting to mitochondrion;GO:0006351//transcription, DNA-templated;GO:1903146//regulation of autophagy of mitochondrion;GO:0045943//positive regulation of transcription from RNA polymerase I promoter;GO:0006364//rRNA processing;GO:2000234//positive regulation of rRNA processing","K14552//NET1-associated nuclear protein 1 (U3 small nucleolar RNA-associated protein 17)","NP_115544.1//WD repeat-containing protein 75 isoform 1 [Homo sapiens];NP_001290025.1//WD repeat-containing protein 75 isoform 2 [Homo sapiens]","1//3;2//1"]
[374786,3762,0.29,0.24,-0.273018494406416,0.678654070335001,"*",0.560546,"EFCAB5","NA","GO:0005509//calcium ion binding","NA","K12022//tripartite motif-containing protein 46;K14000//ribosome-binding protein 1;K04739//cAMP-dependent protein kinase regulator","XP_016880081.1//PREDICTED: EF-hand calcium-binding domain-containing protein 5 isoform X7 [Homo sapiens];NP_940931.2//EF-hand calcium-binding domain-containing protein 5 isoform a [Homo sapiens]","1//3;3//A2MP1"]
[57030,2993,0.93,0.77,-0.27237227041313,0.617528495269987,"*",0.461774,"SLC17A7","GO:0048786//presynaptic active zone;GO:0098794//postsynapse;GO:0060076//excitatory synapse;GO:0030054//cell junction;GO:0044300//cerebellar mossy fiber;GO:0030672//synaptic vesicle membrane;GO:0060203//clathrin-sculpted glutamate transport vesicle membrane;GO:0016021//integral component of membrane;GO:0030285//integral component of synaptic vesicle membrane;GO:0005886//plasma membrane","GO:0005313//L-glutamate transmembrane transporter activity;GO:0015319//sodium:inorganic phosphate symporter activity;GO:0005315//inorganic phosphate transmembrane transporter activity;GO:0015321//sodium-dependent phosphate transmembrane transporter activity;GO:0008068//extracellularly glutamate-gated chloride channel activity","GO:0055085//transmembrane transport;GO:0006811//ion transport;GO:0007420//brain development;GO:0007616//long-term memory;GO:0051938//L-glutamate import;GO:0003407//neural retina development;GO:0098700//neurotransmitter loading into synaptic vesicle;GO:0006817//phosphate ion transport;GO:0042137//sequestering of neurotransmitter;GO:0035249//synaptic transmission, glutamatergic;GO:0097401//synaptic vesicle lumen acidification;GO:0014047//glutamate secretion","K12302//MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6/7/8","NP_064705.1//vesicular glutamate transporter 1 [Homo sapiens]","3//A2MP1"]
[284406,5974,1.92,1.59,-0.272079545436801,0.615672279872633,"*",0.459962,"ZFP82","GO:0005634//nucleus;GO:0005622//intracellular","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","NP_001308848.1//zinc finger protein 82 homolog isoform 4 [Homo sapiens];NP_001308847.1//zinc finger protein 82 homolog isoform 3 [Homo sapiens];XP_014927523.1//PREDICTED: uncharacterized protein LOC106974738 [Acinonyx jubatus]","1//3;3//A2MP1"]
[338707,3463,9.22,7.64,-0.271194112393589,0.0298571347000952,"*",0.01177912,"B4GALNT4","GO:0032580//Golgi cisterna membrane;GO:0016021//integral component of membrane","GO:0033842//N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity;GO:0008376//acetylgalactosaminyltransferase activity","NA","K09657//beta-1,4-N-acetylgalactosaminyltransferase 4 [EC:2.4.1.244]","NP_848632.2//N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 [Homo sapiens]",4]
[11022,2794,4.15,3.44,-0.270702771532189,0.22930685984252,"*",0.127616,"TDRKH","GO:0071547//piP-body;GO:0071546//pi-body;GO:0005739//mitochondrion","GO:0003723//RNA binding","GO:0007140//male meiotic nuclear division;GO:0009566//fertilization;GO:0030154//cell differentiation;GO:0043046//DNA methylation involved in gamete generation;GO:0031047//gene silencing by RNA;GO:0007283//spermatogenesis;GO:0034587//piRNA metabolic process","K18406//tudor domain-containing protein 2","NP_001077433.1//tudor and KH domain-containing protein isoform b [Homo sapiens];AAD30971.1//putative RNA binding protein [Homo sapiens]","1//3;3//A2MP1"]
[10888,4178,0.41,0.34,-0.270089163367744,0.647372546966431,"*",0.52636,"GPR83","GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0097730//non-motile cilium","GO:0004983//neuropeptide Y receptor activity;GO:0004930//G-protein coupled receptor activity","GO:0051384//response to glucocorticoid","K04210//G protein-coupled receptor 83","NP_057624.3//probable G-protein coupled receptor 83 isoform 1 precursor [Homo sapiens];NP_001317274.1//probable G-protein coupled receptor 83 isoform 2 precursor [Homo sapiens]","1//3;3//A2MP1"]
[51144,2556,36.96,30.67,-0.269136590149038,{"v":8.3364763059989e-05,"d":"8.34E-05"},"*",{"v":1.896504e-05,"d":"1.90E-05"},"HSD17B12","GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005578//proteinaceous extracellular matrix","GO:0102341//3-oxo-lignoceroyl-CoA reductase activity;GO:0001968//fibronectin binding;GO:0102340//3-oxo-behenoyl-CoA reductase activity;GO:0102339//3-oxo-arachidoyl-CoA reductase activity;GO:0005518//collagen binding;GO:0102342//3-oxo-cerotoyl-CoA reductase activity;GO:0004303//estradiol 17-beta-dehydrogenase activity;GO:0016509//long-chain-3-hydroxyacyl-CoA dehydrogenase activity;GO:0008201//heparin binding;GO:0016491//oxidoreductase activity","GO:0030198//extracellular matrix organization;GO:0035338//long-chain fatty-acyl-CoA biosynthetic process;GO:0006633//fatty acid biosynthetic process;GO:0006703//estrogen biosynthetic process;GO:0010811//positive regulation of cell-substrate adhesion","K10251//17beta-estradiol 17-dehydrogenase / very-long-chain 3-oxoacyl-CoA reductase [EC:1.1.1.62 1.1.1.330]","NP_057226.1//very-long-chain 3-oxoacyl-CoA reductase [Homo sapiens]","2//1"]
[4173,4803,59.27,49.2,-0.26864374194101,{"v":1.03965907473842E-12,"d":"1.04E-12"},"*",{"v":8.7083e-14,"d":"8.71E-14"},"MCM4","GO:0016020//membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000784//nuclear chromosome, telomeric region;GO:0042555//MCM complex","GO:0003677//DNA binding;GO:0003697//single-stranded DNA binding;GO:0005524//ATP binding;GO:0003678//DNA helicase activity;GO:0004003//ATP-dependent DNA helicase activity","GO:0006260//DNA replication;GO:0000082//G1/S transition of mitotic cell cycle;GO:0006268//DNA unwinding involved in DNA replication;GO:0006270//DNA replication initiation","K02212//DNA replication licensing factor MCM4 [EC:3.6.4.12]","CAA52801.1//P1 Cdc21 protein, partial [Homo sapiens]","3//A2MP1;2//1"]
[93109,2419,4.72,3.92,-0.267933205246633,0.229281068946125,"*",0.127616,"TMEM44","GO:0016020//membrane","NA","NA","NA","NP_001159777.1//transmembrane protein 44 isoform c [Homo sapiens];NP_001011655.1//transmembrane protein 44 isoform b [Homo sapiens];NP_001159778.1//transmembrane protein 44 isoform d [Homo sapiens];NP_612408.3//transmembrane protein 44 isoform a [Homo sapiens]","1//3;4;2//1"]
[1540,8614,1.36,1.13,-0.267283878835152,0.218994498113208,"*",0.1191624,"CYLD","GO:0005874//microtubule;GO:0005813//centrosome;GO:0048471//perinuclear region of cytoplasm;GO:0036064//ciliary basal body;GO:0097542//ciliary tip;GO:0005829//cytosol;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0005819//spindle;GO:0005886//plasma membrane","GO:0061578//Lys63-specific deubiquitinase activity;GO:0004843//thiol-dependent ubiquitin-specific protease activity;GO:0008270//zinc ion binding;GO:0036459//thiol-dependent ubiquitinyl hydrolase activity;GO:1990380//Lys48-specific deubiquitinase activity;GO:0070064//proline-rich region binding;GO:0019901//protein kinase binding","GO:0070507//regulation of microtubule cytoskeleton organization;GO:0007346//regulation of mitotic cell cycle;GO:1902017//regulation of cilium assembly;GO:0010803//regulation of tumor necrosis factor-mediated signaling pathway;GO:1903829//positive regulation of cellular protein localization;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0045581//negative regulation of T cell differentiation;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination;GO:0045582//positive regulation of T cell differentiation;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:0045087//innate immune response;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0070536//protein K63-linked deubiquitination;GO:0043369//CD4-positive or CD8-positive, alpha-beta T cell lineage commitment;GO:0048872//homeostasis of number of cells;GO:0043393//regulation of protein binding;GO:0045577//regulation of B cell differentiation;GO:0070423//nucleotide-binding oligomerization domain containing signaling pathway;GO:1901026//ripoptosome assembly involved in necroptotic process;GO:1990108//protein linear deubiquitination;GO:2001242//regulation of intrinsic apoptotic signaling pathway;GO:0042347//negative regulation of NF-kappaB import into nucleus;GO:0016055//Wnt signaling pathway;GO:0070266//necroptotic process;GO:0032480//negative regulation of type I interferon production;GO:0007049//cell cycle;GO:0050862//positive regulation of T cell receptor signaling pathway","K08601//ubiquitin thioesterase [EC:3.4.19.12]","NP_056062.1//ubiquitin carboxyl-terminal hydrolase CYLD isoform 1 [Homo sapiens];NP_001035814.1//ubiquitin carboxyl-terminal hydrolase CYLD isoform 2 [Homo sapiens]","1//3;2//1"]
[2295,2187,16.3,13.55,-0.266579112877206,0.0242520644617886,"*",0.00933706,"FOXF2","GO:0005634//nucleus;GO:0005667//transcription factor complex","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0008134//transcription factor binding;GO:0003700//DNA binding transcription factor activity;GO:0003705//transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0009653//anatomical structure morphogenesis;GO:0030154//cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0042249//establishment of planar polarity of embryonic epithelium;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0030198//extracellular matrix organization;GO:0048806//genitalia development;GO:0048566//embryonic digestive tract development;GO:0001837//epithelial to mesenchymal transition;GO:0060021//palate development;GO:0048596//embryonic camera-type eye morphogenesis","K09399//forkhead box protein F","NP_001443.1//forkhead box protein F2 [Homo sapiens]","1//3"]
[23032,4440,7.12,5.92,-0.266280065337448,0.033148299155194,"*",0.0132643,"USP33","GO:0005654//nucleoplasm;GO:0005925//focal adhesion;GO:0030891//VCB complex;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0044297//cell body;GO:0005829//cytosol;GO:0005794//Golgi apparatus","GO:0004843//thiol-dependent ubiquitin-specific protease activity;GO:0001664//G-protein coupled receptor binding;GO:0004197//cysteine-type endopeptidase activity;GO:0008270//zinc ion binding;GO:0036459//thiol-dependent ubiquitinyl hydrolase activity;GO:0017160//Ral GTPase binding","GO:0071108//protein K48-linked deubiquitination;GO:0016477//cell migration;GO:0009267//cellular response to starvation;GO:0051298//centrosome duplication;GO:0032092//positive regulation of protein binding;GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0032091//negative regulation of protein binding;GO:0006897//endocytosis;GO:0016579//protein deubiquitination;GO:0010506//regulation of autophagy;GO:0050821//protein stabilization;GO:0007411//axon guidance;GO:0070536//protein K63-linked deubiquitination","K11848//ubiquitin carboxyl-terminal hydrolase 20/33 [EC:3.4.19.12]","NP_963920.1//ubiquitin carboxyl-terminal hydrolase 33 isoform 3 [Homo sapiens];NP_055832.3//ubiquitin carboxyl-terminal hydrolase 33 isoform 1 [Homo sapiens]","4;2//1"]
[10058,3045,14.11,11.74,-0.265285579487212,0.0196162642969403,"*",0.00734474,"ABCB6","NA","NA","NA","K05661//ATP-binding cassette, subfamily B (MDR/TAP), member 6","AAG33617.1//ATP-binding cassette half-transporter [Homo sapiens];NP_001336757.1//ATP-binding cassette sub-family B member 6, mitochondrial isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[8562,2731,33.71,28.06,-0.264661618364311,0.000137916461278394,"*",{"v":3.26876e-05,"d":"3.27E-05"},"DENR","NA","GO:0003743//translation initiation factor activity","NA","K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K02927//large subunit ribosomal protein L40e;K01064//wingless-type MMTV integration site family, member 9","XP_021018633.1//density-regulated protein isoform X1 [Mus caroli]",4]
[9909,5688,19.85,16.53,-0.264052282738006,{"v":1.86758654478073e-05,"d":"1.87E-05"},"*",{"v":3.78568e-06,"d":"3.79E-06"},"DENND4B","GO:0005634//nucleus;GO:0005794//Golgi apparatus;GO:0005829//cytosol","GO:0017112//Rab guanyl-nucleotide exchange factor activity","GO:0032483//regulation of Rab protein signal transduction;GO:0061024//membrane organization","K20163//DENN domain-containing protein 4","XP_005245735.1//PREDICTED: DENN domain-containing protein 4B isoform X3 [Homo sapiens]","2//1"]
[9122,2006,16.07,13.39,-0.263213968350783,0.0124331952194606,"*",4.41552E-3,"SLC16A4","GO:0016020//membrane;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane","GO:0008028//monocarboxylic acid transmembrane transporter activity;GO:0015293//symporter activity","GO:0055085//transmembrane transport;GO:0015718//monocarboxylic acid transport","K08181//MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 4","NP_001188477.1//monocarboxylate transporter 5 isoform 4 [Homo sapiens];NP_001306149.1//monocarboxylate transporter 5 isoform 6 [Homo sapiens];NP_001188478.1//monocarboxylate transporter 5 isoform 5 [Homo sapiens];NP_001188475.1//monocarboxylate transporter 5 isoform 2 [Homo sapiens];NP_004687.1//monocarboxylate transporter 5 isoform 1 [Homo sapiens];NP_001188476.1//monocarboxylate transporter 5 isoform 3 [Homo sapiens]","1//3;2//1"]
[165055,2262,3.3,2.75,-0.263034405833794,0.33139061375,"*",0.199158,"CCDC138","NA","NA","NA","K21110//cingulin-like protein 1;K11167//dehydrogenase/reductase SDR family member 7C [EC:1.1.-.-];K10421//CAP-Gly domain-containing linker protein 1;K16461//centrosomal protein CEP135;K20478//golgin subfamily B member 1","NP_001338490.1//coiled-coil domain-containing protein 138 isoform 14 [Homo sapiens];NP_001338480.1//coiled-coil domain-containing protein 138 isoform 8 [Homo sapiens];NP_001338486.1//coiled-coil domain-containing protein 138 isoform 12 [Homo sapiens];NP_001338473.1//coiled-coil domain-containing protein 138 isoform 4 [Homo sapiens];NP_001338482.1//coiled-coil domain-containing protein 138 isoform 9 [Homo sapiens];NP_001338477.1//coiled-coil domain-containing protein 138 isoform 6 [Homo sapiens];NP_001338483.1//coiled-coil domain-containing protein 138 isoform 10 [Homo sapiens];NP_001338474.1//coiled-coil domain-containing protein 138 isoform 5 [Homo sapiens];NP_001338484.1//coiled-coil domain-containing protein 138 isoform 11 [Homo sapiens];NP_001338488.1//coiled-coil domain-containing protein 138 isoform 13 [Homo sapiens];NP_001290034.1//coiled-coil domain-containing protein 138 isoform 2 [Homo sapiens];NP_659415.1//coiled-coil domain-containing protein 138 isoform 1 [Homo sapiens];NP_001338478.1//coiled-coil domain-containing protein 138 isoform 7 [Homo sapiens]","1//3;2//1"]
[23543,6800,13.21,11.01,-0.262815997682459,0.000307467393449132,"*",{"v":7.75694e-05,"d":"7.76E-05"},"RBFOX2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003714//transcription corepressor activity;GO:0008134//transcription factor binding","GO:0043484//regulation of RNA splicing;GO:0016070//RNA metabolic process;GO:0007399//nervous system development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006397//mRNA processing;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0010724//regulation of definitive erythrocyte differentiation;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0042127//regulation of cell proliferation;GO:0021942//radial glia guided migration of Purkinje cell;GO:0048813//dendrite morphogenesis;GO:0008380//RNA splicing;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0050885//neuromuscular process controlling balance","K14946//RNA binding protein fox-1","NP_001076048.1//RNA binding protein fox-1 homolog 2 isoform 6 [Homo sapiens];NP_001076047.1//RNA binding protein fox-1 homolog 2 isoform 5 [Homo sapiens];NP_001336912.1//RNA binding protein fox-1 homolog 2 isoform 7 [Homo sapiens];NP_001026865.1//RNA binding protein fox-1 homolog 2 isoform 1 [Homo sapiens];NP_001336923.1//RNA binding protein fox-1 homolog 2 isoform 13 [Homo sapiens];NP_001336928.1//RNA binding protein fox-1 homolog 2 isoform 18 [Homo sapiens];NP_001336911.1//RNA binding protein fox-1 homolog 2 isoform 8 [Homo sapiens];NP_055124.1//RNA binding protein fox-1 homolog 2 isoform 2 [Homo sapiens];NP_001336927.1//RNA binding protein fox-1 homolog 2 isoform 17 [Homo sapiens];NP_001336920.1//RNA binding protein fox-1 homolog 2 isoform 11 [Homo sapiens];NP_001336925.1//RNA binding protein fox-1 homolog 2 isoform 15 [Homo sapiens];NP_001336926.1//RNA binding protein fox-1 homolog 2 isoform 16 [Homo sapiens];NP_001336924.1//RNA binding protein fox-1 homolog 2 isoform 14 [Homo sapiens];NP_001336921.1//RNA binding protein fox-1 homolog 2 isoform 12 [Homo sapiens];NP_001076046.1//RNA binding protein fox-1 homolog 2 isoform 4 [Homo sapiens];NP_001076045.1//RNA binding protein fox-1 homolog 2 isoform 3 [Homo sapiens];AAI49448.1//RBM9 protein, partial [Bos taurus];NP_001336918.1//RNA binding protein fox-1 homolog 2 isoform 9 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[1315,3419,35.18,29.33,-0.262378411715005,{"v":1.10024571739827e-05,"d":"1.10E-05"},"*",{"v":2.14966e-06,"d":"2.15E-06"},"COPB1","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0030667//secretory granule membrane;GO:0030126//COPI vesicle coat;GO:0019028//viral capsid;GO:0101003//ficolin-1-rich granule membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0000139//Golgi membrane;GO:0030133//transport vesicle;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0005798//Golgi-associated vesicle;GO:0005789//endoplasmic reticulum membrane;GO:0070821//tertiary granule membrane;GO:0005886//plasma membrane","GO:0005198//structural molecule activity","GO:0006886//intracellular protein transport;GO:0043312//neutrophil degranulation;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0016032//viral process;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0016192//vesicle-mediated transport","K17301//coatomer subunit beta","NP_057535.1//coatomer subunit beta [Homo sapiens]","4;1//3"]
[5480,1241,7.56,6.31,-0.260746229238524,0.328024488596491,"*",0.1966422,"PPIC","GO:0070062//extracellular exosome;GO:0005737//cytoplasm","GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0016018//cyclosporin A binding","GO:0006457//protein folding","K09563//peptidyl-prolyl isomerase C (cyclophilin C) [EC:5.2.1.8]","NP_000934.1//peptidyl-prolyl cis-trans isomerase C precursor [Homo sapiens]",4]
[88455,3917,4.54,3.79,-0.260494449119823,0.142104751886085,"*",0.0712214,"ANKRD13A","NA","NA","NA","K21437//ankyrin repeat domain-containing protein 13","XP_008002866.1//PREDICTED: ankyrin repeat domain-containing protein 13A isoform X2 [Chlorocebus sabaeus]","1//3"]
[5255,6138,8.49,7.09,-0.259978926313522,0.00592433626371106,"*",0.001940782,"PHKA1","NA","NA","NA","K07190//phosphorylase kinase alpha/beta subunit","XP_003944502.1//PREDICTED: phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform isoform X1 [Saimiri boliviensis boliviensis];XP_003944500.1//PREDICTED: phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform isoform X2 [Saimiri boliviensis boliviensis];XP_003944501.1//PREDICTED: phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform isoform X4 [Saimiri boliviensis boliviensis]","1//3;3//A2MP1"]
[26273,2162,4.93,4.12,-0.258943309194693,0.463655135275081,"*",0.313912,"FBXO3","GO:0005654//nucleoplasm;GO:0005829//cytosol","GO:0004842//ubiquitin-protein transferase activity","GO:0006508//proteolysis","K10290//F-box protein 3","XP_021541023.1//F-box only protein 3 isoform X1 [Neomonachus schauinslandi];NP_208385.1//F-box only protein 3 isoform 2 [Homo sapiens]","3//A2MP1;2//1"]
[283742,4392,4.33,3.62,-0.25837732764352,0.133992389089531,"*",0.0664258,"FAM98B","NA","NA","NA","K15434//protein FAM98B","XP_008015284.1//PREDICTED: protein FAM98B [Chlorocebus sabaeus]","3//A2MP1"]
[6767,3597,53.13,44.43,-0.257992571463067,{"v":3.30676536162362e-08,"d":"3.31E-08"},"*",{"v":4.48796e-09,"d":"4.49E-09"},"ST13","GO:0070062//extracellular exosome;GO:0043234//protein complex;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0030674//protein binding, bridging;GO:0042802//identical protein binding;GO:0051087//chaperone binding;GO:0046983//protein dimerization activity;GO:0019904//protein domain specific binding;GO:0051082//unfolded protein binding;GO:0030544//Hsp70 protein binding;GO:0032564//dATP binding;GO:0032403//protein complex binding","GO:0006457//protein folding;GO:0051260//protein homooligomerization;GO:0061084//negative regulation of protein refolding","K09560//suppressor of tumorigenicity protein 13","NP_003923.2//hsc70-interacting protein isoform 1 [Homo sapiens];NP_001265518.1//hsc70-interacting protein isoform 2 [Homo sapiens]","4;1//3"]
[9798,3915,26.11,21.85,-0.256969177924881,{"v":2.41451841992883E-6,"d":"2.41E-06"},"*",{"v":4.2474e-07,"d":"4.25E-07"},"IST1","GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0005635//nuclear envelope;GO:0005813//centrosome;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0030496//midbody;GO:0090543//Flemming body;GO:0035578//azurophil granule lumen;GO:0005829//cytosol;GO:0005576//extracellular region","GO:0090541//MIT domain binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0032403//protein complex binding;GO:0045296//cadherin binding","GO:0045184//establishment of protein localization;GO:0019076//viral release from host cell;GO:0045862//positive regulation of proteolysis;GO:0009838//abscission;GO:0000910//cytokinesis;GO:1904903//ESCRT III complex disassembly;GO:0036258//multivesicular body assembly;GO:0046745//viral capsid secondary envelopment;GO:0051301//cell division;GO:0008104//protein localization;GO:0043312//neutrophil degranulation;GO:0048672//positive regulation of collateral sprouting;GO:0015031//protein transport","K19476//vacuolar protein sorting-associated protein IST1","NP_001257904.1//IST1 homolog isoform a [Homo sapiens];NP_055576.2//IST1 homolog isoform b [Homo sapiens];NP_001257905.1//IST1 homolog isoform c [Homo sapiens];EAW59209.1//KIAA0174, isoform CRA_e [Homo sapiens]","1//3;3//A2MP1"]
[25862,7468,1.78,1.49,-0.256564910504236,0.309451314678511,"*",0.1831834,"USP49","GO:0005654//nucleoplasm","GO:0042393//histone binding;GO:0004843//thiol-dependent ubiquitin-specific protease activity;GO:0004197//cysteine-type endopeptidase activity;GO:0008270//zinc ion binding;GO:0036459//thiol-dependent ubiquitinyl hydrolase activity","GO:0006511//ubiquitin-dependent protein catabolic process;GO:0000398//mRNA splicing, via spliceosome;GO:0016579//protein deubiquitination;GO:0035616//histone H2B conserved C-terminal lysine deubiquitination","K11834//ubiquitin carboxyl-terminal hydrolase 44/49 [EC:3.4.19.12]","NP_001273483.1//ubiquitin carboxyl-terminal hydrolase 49 isoform a [Homo sapiens];NP_061031.2//ubiquitin carboxyl-terminal hydrolase 49 isoform b [Homo sapiens]","1//3;4"]
[92906,3038,7.5,6.28,-0.256126036491616,0.110905019770962,"*",0.0527448,"HNRNPLL","GO:0016020//membrane;GO:0005634//nucleus;GO:0030529//intracellular ribonucleoprotein complex;GO:0019013//viral nucleocapsid","GO:0003723//RNA binding;GO:0003729//mRNA binding","GO:0033120//positive regulation of RNA splicing;GO:0006397//mRNA processing","K13159//heterogeneous nuclear ribonucleoprotein L","NP_001136122.1//heterogeneous nuclear ribonucleoprotein L-like isoform 2 [Homo sapiens];NP_612403.2//heterogeneous nuclear ribonucleoprotein L-like isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[4594,3886,2.53,2.12,-0.255073120131111,0.319947450036684,"*",0.1910992,"MUT","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0046872//metal ion binding;GO:0004494//methylmalonyl-CoA mutase activity;GO:0031419//cobalamin binding;GO:0072341//modified amino acid binding","GO:0019626//short-chain fatty acid catabolic process;GO:0008152//metabolic process;GO:0009791//post-embryonic development;GO:0050667//homocysteine metabolic process;GO:0009235//cobalamin metabolic process","K01847//methylmalonyl-CoA mutase [EC:5.4.99.2]","NP_000246.2//methylmalonyl-CoA mutase, mitochondrial precursor [Homo sapiens]","3//A2MP1"]
[51094,2052,76.09,63.77,-0.254828981225258,{"v":1.31823420474777e-06,"d":"1.32E-06"},"*",{"v":2.22484E-7,"d":"2.22E-07"},"ADIPOR1","GO:0016020//membrane;GO:0031226//intrinsic component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0097003//adipokinetic hormone receptor activity;GO:0004872//receptor activity;GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity;GO:0042562//hormone binding;GO:0019901//protein kinase binding;GO:0055100//adiponectin binding;GO:0046872//metal ion binding","GO:0030308//negative regulation of cell growth;GO:0019395//fatty acid oxidation;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0046628//positive regulation of insulin receptor signaling pathway;GO:0046426//negative regulation of JAK-STAT cascade;GO:0010633//negative regulation of epithelial cell migration;GO:0042593//glucose homeostasis;GO:0046427//positive regulation of JAK-STAT cascade;GO:0033211//adiponectin-activated signaling pathway;GO:0042304//regulation of fatty acid biosynthetic process;GO:1901223//negative regulation of NIK/NF-kappaB signaling;GO:0019216//regulation of lipid metabolic process;GO:0010906//regulation of glucose metabolic process;GO:0033210//leptin-mediated signaling pathway;GO:0009755//hormone-mediated signaling pathway","K07297//adiponectin receptor","OWK08412.1//hypothetical protein Celaphus_00011293 [Cervus elaphus hippelaphus]","1//3;5"]
[1353,2468,27.16,22.78,-0.25371573253662,0.000520433677061611,"*",1.374878E-4,"COX11","GO:0043234//protein complex;GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion","GO:0009055//electron transfer activity;GO:0004129//cytochrome-c oxidase activity;GO:0005507//copper ion binding","GO:0055065//metal ion homeostasis;GO:0007585//respiratory gaseous exchange;GO:0008535//respiratory chain complex IV assembly;GO:0033132//negative regulation of glucokinase activity","K02258//cytochrome c oxidase assembly protein subunit 11","NP_001156333.1//cytochrome c oxidase assembly protein COX11, mitochondrial isoform 2 [Homo sapiens];NP_004366.1//cytochrome c oxidase assembly protein COX11, mitochondrial isoform 1 [Homo sapiens];NP_001308447.1//cytochrome c oxidase assembly protein COX11, mitochondrial isoform 4 [Homo sapiens];NP_001156334.1//cytochrome c oxidase assembly protein COX11, mitochondrial isoform 3 [Homo sapiens]","1//3;4;2//1"]
[79009,2575,9.46,7.94,-0.252701176196438,0.0888165704409363,"*",0.0408554,"DDX50","GO:0016020//membrane;GO:0005730//nucleolus;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0004004//ATP-dependent RNA helicase activity;GO:0005524//ATP binding;GO:0004386//helicase activity","GO:0010501//RNA secondary structure unwinding","K13183//ATP-dependent RNA helicase DDX50 [EC:3.6.4.13]","NP_076950.1//ATP-dependent RNA helicase DDX50 [Homo sapiens]","1//3"]
[9672,5121,8.66,7.27,-0.252411660807131,0.0154100756544232,"*",0.00559428,"SDC3","NA","NA","NA","K16337//syndecan 3","XP_017381434.1//PREDICTED: syndecan-3 isoform X2 [Cebus capucinus imitator]","3//A2MP1"]
[55260,2546,6.43,5.4,-0.251859330277116,0.158701319599707,"*",0.0814072,"TMEM143","GO:0016021//integral component of membrane;GO:0005739//mitochondrion","NA","NA","K19719//collagen, type II, alpha;K16628//collagen, type VII, alpha;K06236//collagen, type I, alpha;K22020//mucin-19;K19720//collagen, type III, alpha","NP_001290468.1//transmembrane protein 143 isoform c [Homo sapiens];NP_001290469.1//transmembrane protein 143 isoform d [Homo sapiens];NP_001290467.1//transmembrane protein 143 isoform b [Homo sapiens];NP_060743.2//transmembrane protein 143 isoform a [Homo sapiens]","1//3;3//A2MP1"]
[7481,1927,0.25,0.21,-0.251538766995965,0.850104312307376,"*",0.777036,"WNT11","GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005578//proteinaceous extracellular matrix","GO:0030295//protein kinase activator activity;GO:0005102//receptor binding;GO:0044212//transcription regulatory region DNA binding;GO:0005096//GTPase activator activity;GO:0005109//frizzled binding","GO:0001649//osteoblast differentiation;GO:0060412//ventricular septum morphogenesis;GO:0030335//positive regulation of cell migration;GO:0071260//cellular response to mechanical stimulus;GO:0061053//somite development;GO:0061101//neuroendocrine cell differentiation;GO:0032915//positive regulation of transforming growth factor beta2 production;GO:0003402//planar cell polarity pathway involved in axis elongation;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0060675//ureteric bud morphogenesis;GO:0043065//positive regulation of apoptotic process;GO:0072177//mesonephric duct development;GO:0001837//epithelial to mesenchymal transition;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006468//protein phosphorylation;GO:0072201//negative regulation of mesenchymal cell proliferation;GO:0043066//negative regulation of apoptotic process;GO:0010628//positive regulation of gene expression;GO:0003151//outflow tract morphogenesis;GO:0071300//cellular response to retinoic acid;GO:0060070//canonical Wnt signaling pathway;GO:0070830//bicellular tight junction assembly;GO:0061037//negative regulation of cartilage development;GO:0030325//adrenal gland development;GO:0016055//Wnt signaling pathway;GO:0048706//embryonic skeletal system development;GO:0060197//cloacal septation;GO:0034394//protein localization to cell surface;GO:0060775//planar cell polarity pathway involved in gastrula mediolateral intercalation;GO:0043547//positive regulation of GTPase activity;GO:0045893//positive regulation of transcription, DNA-templated;GO:0007223//Wnt signaling pathway, calcium modulating pathway;GO:0060484//lung-associated mesenchyme development;GO:0048341//paraxial mesoderm formation;GO:0060021//palate development;GO:0090037//positive regulation of protein kinase C signaling;GO:0060028//convergent extension involved in axis elongation;GO:0045165//cell fate commitment;GO:0030308//negative regulation of cell growth;GO:0030282//bone mineralization;GO:0030182//neuron differentiation;GO:0030336//negative regulation of cell migration;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0051496//positive regulation of stress fiber assembly;GO:0048844//artery morphogenesis;GO:0090272//negative regulation of fibroblast growth factor production;GO:0031667//response to nutrient levels;GO:0048570//notochord morphogenesis;GO:0060548//negative regulation of cell death;GO:0045199//maintenance of epithelial cell apical/basal polarity","K01384//wingless-type MMTV integration site family, member 11","XP_020747150.1//protein Wnt-11 [Odocoileus virginianus texanus]","2//1"]
[111,5123,0.25,0.21,-0.251538766995965,0.922338165381547,"*",0.86864,"ADCY5","GO:0005929//cilium;GO:0045111//intermediate filament cytoskeleton;GO:0005622//intracellular;GO:0016021//integral component of membrane;GO:0008074//guanylate cyclase complex, soluble;GO:0005886//plasma membrane","GO:0005524//ATP binding;GO:0046982//protein heterodimerization activity;GO:0008179//adenylate cyclase binding;GO:0097110//scaffold protein binding;GO:0046872//metal ion binding;GO:0004016//adenylate cyclase activity;GO:0000166//nucleotide binding;GO:0004383//guanylate cyclase activity","GO:1904322//cellular response to forskolin;GO:0035556//intracellular signal transduction;GO:0001973//adenosine receptor signaling pathway;GO:0007195//adenylate cyclase-inhibiting dopamine receptor signaling pathway;GO:0061178//regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0007191//adenylate cyclase-activating dopamine receptor signaling pathway;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0071377//cellular response to glucagon stimulus;GO:0006171//cAMP biosynthetic process;GO:0006182//cGMP biosynthetic process;GO:0007190//activation of adenylate cyclase activity;GO:0007626//locomotory behavior;GO:0034199//activation of protein kinase A activity;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0050885//neuromuscular process controlling balance;GO:0003091//renal water homeostasis","K08045//adenylate cyclase 5 [EC:4.6.1.1]","NP_899200.1//adenylate cyclase type 5 isoform 1 [Homo sapiens];NP_001186571.1//adenylate cyclase type 5 isoform 2 [Homo sapiens]","1//3;2//1"]
[9289,3797,48.95,41.14,-0.250767065966124,{"v":9.77219020479303e-08,"d":"9.77E-08"},"*",{"v":1.40398e-08,"d":"1.40E-08"},"ADGRG1","GO:0070062//extracellular exosome;GO:0045121//membrane raft;GO:0005887//integral component of plasma membrane;GO:0097451//glial limiting end-foot;GO:0005622//intracellular;GO:0016021//integral component of membrane","GO:0005518//collagen binding;GO:0008201//heparin binding;GO:0050840//extracellular matrix binding;GO:0004930//G-protein coupled receptor activity","GO:0016477//cell migration;GO:0045785//positive regulation of cell adhesion;GO:0021801//cerebral cortex radial glia guided migration;GO:0007166//cell surface receptor signaling pathway;GO:0007420//brain development;GO:0010573//vascular endothelial growth factor production;GO:0021819//layer formation in cerebral cortex;GO:0008285//negative regulation of cell proliferation;GO:0007186//G-protein coupled receptor signaling pathway;GO:0001525//angiogenesis;GO:0021796//cerebral cortex regionalization;GO:0070528//protein kinase C signaling;GO:0007267//cell-cell signaling;GO:2000179//positive regulation of neural precursor cell proliferation;GO:0007266//Rho protein signal transduction;GO:0007155//cell adhesion;GO:2001223//negative regulation of neuron migration;GO:0035025//positive regulation of Rho protein signal transduction;GO:0072520//seminiferous tubule development","K08450//G protein-coupled receptor 56","NP_005673.3//adhesion G-protein coupled receptor G1 isoform a precursor [Homo sapiens];NP_958933.1//adhesion G-protein coupled receptor G1 isoform b precursor [Homo sapiens];NP_001277071.1//adhesion G-protein coupled receptor G1 isoform d precursor [Homo sapiens];NP_001139245.1//adhesion G-protein coupled receptor G1 isoform c precursor [Homo sapiens]","6;1//3;3//A2MP1;2//1"]
[23212,1724,43.2,36.32,-0.250267109759916,0.00146387037175043,"*",0.000423014,"RRS1","GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005730//nucleolus;GO:0000794//condensed nuclear chromosome;GO:0001650//fibrillar center;GO:0030687//preribosome, large subunit precursor","GO:0003723//RNA binding;GO:0008097//5S rRNA binding","GO:0002244//hematopoietic progenitor cell differentiation;GO:0000027//ribosomal large subunit assembly;GO:0000447//endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:1901796//regulation of signal transduction by p53 class mediator;GO:0000055//ribosomal large subunit export from nucleus;GO:0042254//ribosome biogenesis;GO:0007080//mitotic metaphase plate congression;GO:0042273//ribosomal large subunit biogenesis;GO:1902570//protein localization to nucleolus","K14852//regulator of ribosome biosynthesis","NP_055984.1//ribosome biogenesis regulatory protein homolog [Homo sapiens]","3//A2MP1"]
[285237,2782,7.36,6.19,-0.249766356842748,0.127964891202873,"*",0.0624684,"C3orf38","GO:0005634//nucleus","NA","GO:0043065//positive regulation of apoptotic process;GO:0006915//apoptotic process","K09291//nucleoprotein TPR;K12396//AP-3 complex subunit delta","NP_776185.2//uncharacterized protein C3orf38 [Homo sapiens]","3//A2MP1"]
[50624,2279,0.63,0.53,-0.249359468936717,0.724668135004822,"*",0.611572,"CUZD1","GO:0042589//zymogen granule membrane;GO:0030658//transport vesicle membrane;GO:0016021//integral component of membrane","NA","GO:0006931//substrate-dependent cell migration, cell attachment to substrate;GO:0008283//cell proliferation;GO:0051301//cell division;GO:0032023//trypsinogen activation;GO:0007049//cell cycle","K13912//deleted in malignant brain tumors 1 protein","NP_071317.2//CUB and zona pellucida-like domain-containing protein 1 precursor [Homo sapiens]",5]
[148156,3577,1.83,1.54,-0.248913297589141,0.491066475306958,"*",0.338004,"ZNF558","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","XP_020834727.1//LOW QUALITY PROTEIN: zinc finger protein 420-like [Phascolarctos cinereus]","1//3;2//1"]
[342926,3615,2.91,2.45,-0.248237403905713,0.33886860594757,"*",0.204734,"ZNF677","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","XP_019663848.1//PREDICTED: zinc finger protein 677-like isoform X1 [Ailuropoda melanoleuca]","1//3;3//A2MP1"]
[83698,9500,0.19,0.16,-0.247927513443586,0.666494147622319,"*",0.546622,"CALN1","GO:0032588//trans-Golgi network membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0048471//perinuclear region of cytoplasm","GO:0005509//calcium ion binding","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K02183//calmodulin","EDL19465.1//calneuron 1, isoform CRA_c, partial [Mus musculus];NP_113656.2//calcium-binding protein 8 isoform 1 [Homo sapiens]","3//A2MP1;2//1"]
[27154,6054,7.49,6.31,-0.247325713476202,0.0169483350690066,"*",6.22698E-3,"BRPF3","GO:0005829//cytosol;GO:0005576//extracellular region;GO:0070776//MOZ/MORF histone acetyltransferase complex","GO:0046872//metal ion binding","GO:0002576//platelet degranulation;GO:0043966//histone H3 acetylation","K11350//bromodomain and PHD finger-containing protein 3","NP_056510.2//bromodomain and PHD finger-containing protein 3 [Homo sapiens]","2//1"]
[9942,3083,4.84,4.08,-0.246437895303099,0.24729608164985,"*",0.1396246,"XYLB","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0004856//xylulokinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016773//phosphotransferase activity, alcohol group as acceptor","GO:0019640//glucuronate catabolic process to xylulose 5-phosphate;GO:0005997//xylulose metabolic process;GO:0006091//generation of precursor metabolites and energy;GO:0005975//carbohydrate metabolic process;GO:0042732//D-xylose metabolic process;GO:0005998//xylulose catabolic process","K00854//xylulokinase [EC:2.7.1.17]","EAW64532.1//xylulokinase homolog (H. influenzae), isoform CRA_b [Homo sapiens];NP_005099.2//xylulose kinase isoform 2 [Homo sapiens];XP_011532627.1//PREDICTED: xylulose kinase isoform X1 [Homo sapiens];NP_001336109.1//xylulose kinase isoform 4 [Homo sapiens]","1//3;3//A2MP1"]
[284656,2095,3.51,2.96,-0.245873854675611,0.377957280610197,"*",0.235756,"EPHA10","GO:0070062//extracellular exosome;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005524//ATP binding;GO:0005003//ephrin receptor activity;GO:0005005//transmembrane-ephrin receptor activity","GO:0048013//ephrin receptor signaling pathway","K08897//Eph receptor A10 [EC:2.7.10.1]","NP_775912.2//ephrin type-A receptor 10 isoform 2 precursor [Homo sapiens];NP_001092909.1//ephrin type-A receptor 10 isoform 3 precursor [Homo sapiens]","1//3;2//1"]
[23395,4203,5.56,4.69,-0.245496960208131,0.108377446153846,"*",0.0513324,"LARS2","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0004823//leucine-tRNA ligase activity;GO:0005524//ATP binding;GO:0002161//aminoacyl-tRNA editing activity","GO:0006418//tRNA aminoacylation for protein translation;GO:0032543//mitochondrial translation;GO:0006429//leucyl-tRNA aminoacylation","K01869//leucyl-tRNA synthetase [EC:6.1.1.4]","NP_056155.1//probable leucine--tRNA ligase, mitochondrial [Homo sapiens]","3//A2MP1"]
[84959,6917,16.07,13.56,-0.24501275053875,{"v":8.6318636254805e-05,"d":"8.63E-05"},"*",{"v":1.968026e-05,"d":"1.97E-05"},"UBASH3B","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0042802//identical protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0004725//protein tyrosine phosphatase activity;GO:0051219//phosphoprotein binding","GO:0045671//negative regulation of osteoclast differentiation;GO:0043393//regulation of protein binding;GO:0051279//regulation of release of sequestered calcium ion into cytosol;GO:0009968//negative regulation of signal transduction;GO:0045779//negative regulation of bone resorption;GO:0038063//collagen-activated tyrosine kinase receptor signaling pathway;GO:0006469//negative regulation of protein kinase activity;GO:0070527//platelet aggregation;GO:0090331//negative regulation of platelet aggregation","K18993//ubiquitin-associated and SH3 domain-containing protein [EC:3.1.3.48]","NP_116262.2//ubiquitin-associated and SH3 domain-containing protein B [Homo sapiens]",4]
[4175,3791,28.36,23.94,-0.244434380296014,1.27200464804469E-4,"*",{"v":2.99328e-05,"d":"2.99E-05"},"MCM6","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000784//nuclear chromosome, telomeric region;GO:0042555//MCM complex","GO:0003677//DNA binding;GO:0003697//single-stranded DNA binding;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0003678//DNA helicase activity;GO:0004003//ATP-dependent DNA helicase activity","GO:0006260//DNA replication;GO:0000082//G1/S transition of mitotic cell cycle;GO:0006268//DNA unwinding involved in DNA replication;GO:0006270//DNA replication initiation","K02542//DNA replication licensing factor MCM6 [EC:3.6.4.12]","NP_005906.2//DNA replication licensing factor MCM6 [Homo sapiens]",5]
[6924,4959,8.93,7.54,-0.244095651852559,0.0198829223509768,"*",7.45454E-3,"ELOA","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005615//extracellular space;GO:0016021//integral component of membrane;GO:0070449//elongin complex","GO:0003746//translation elongation factor activity","GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006355//regulation of transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter","K15076//transcription elongation factor B, polypeptide 3","NP_003189.2//elongin-A [Homo sapiens]","2//1"]
[54600,2395,53.34,45.08,-0.242730309378705,{"v":3.20322367901235E-5,"d":"3.20E-05"},"*",{"v":6.82194e-06,"d":"6.82E-06"},"UGT1A9","GO:0070062//extracellular exosome;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0046982//protein heterodimerization activity;GO:0015020//glucuronosyltransferase activity;GO:0042803//protein homodimerization activity;GO:0008144//drug binding;GO:0004857//enzyme inhibitor activity;GO:0005504//fatty acid binding;GO:0005496//steroid binding;GO:0019899//enzyme binding;GO:0001972//retinoic acid binding","GO:0045939//negative regulation of steroid metabolic process;GO:2001030//negative regulation of cellular glucuronidation;GO:0008152//metabolic process;GO:0052697//xenobiotic glucuronidation;GO:0006805//xenobiotic metabolic process;GO:0017144//drug metabolic process;GO:0008202//steroid metabolic process;GO:0042573//retinoic acid metabolic process;GO:0052695//cellular glucuronidation;GO:0009804//coumarin metabolic process;GO:0006631//fatty acid metabolic process;GO:0045922//negative regulation of fatty acid metabolic process;GO:0019216//regulation of lipid metabolic process;GO:1904224//negative regulation of glucuronosyltransferase activity;GO:0051552//flavone metabolic process;GO:0052696//flavonoid glucuronidation","K00699//glucuronosyltransferase [EC:2.4.1.17]","NP_066307.1//UDP-glucuronosyltransferase 1-9 precursor [Homo sapiens]","2//1"]
[9869,4095,8.21,6.94,-0.242446559199544,0.0920562077225308,"*",0.0425358,"SETDB1","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005694//chromosome;GO:0005886//plasma membrane","GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0008270//zinc ion binding;GO:1990841//promoter-specific chromatin binding;GO:0018024//histone-lysine N-methyltransferase activity","GO:0006351//transcription, DNA-templated;GO:0090309//positive regulation of methylation-dependent chromatin silencing;GO:0033273//response to vitamin;GO:0007265//Ras protein signal transduction;GO:0045471//response to ethanol","K11421//histone-lysine N-methyltransferase SETDB1 [EC:2.1.1.43]","NP_036564.3//histone-lysine N-methyltransferase SETDB1 isoform 2 [Homo sapiens];XP_008968703.1//PREDICTED: histone-lysine N-methyltransferase SETDB1 isoform X2 [Pan paniscus];NP_001230420.1//histone-lysine N-methyltransferase SETDB1 isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[148252,3412,2.59,2.19,-0.242021228085381,0.385641589292849,"*",0.241708,"DIRAS1","NA","NA","NA","K07840//DIRAS family, GTP-binding Ras-like 1","XP_010347728.1//PREDICTED: GTP-binding protein Di-Ras1 [Saimiri boliviensis boliviensis]","3//A2MP1"]
[5154,2762,6.5,5.5,-0.241008099503795,0.172735241803279,"*",0.089709,"PDGFA","NA","NA","NA","K04359//platelet-derived growth factor subunit A","XP_011513718.1//PREDICTED: platelet-derived growth factor subunit A isoform X2 [Homo sapiens];XP_011513720.1//PREDICTED: platelet-derived growth factor subunit A isoform X4 [Homo sapiens]","4;5"]
[11011,5592,8,6.77,-0.240844166199728,3.37446662733293E-3,"*",1.052646E-3,"TLK2","GO:0005634//nucleus;GO:0005882//intermediate filament;GO:0048471//perinuclear region of cytoplasm","GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding","GO:0007059//chromosome segregation;GO:0006468//protein phosphorylation;GO:0001672//regulation of chromatin assembly or disassembly;GO:0035556//intracellular signal transduction;GO:0071480//cellular response to gamma radiation;GO:0018105//peptidyl-serine phosphorylation;GO:0016569//covalent chromatin modification;GO:0010507//negative regulation of autophagy;GO:0007049//cell cycle;GO:0006974//cellular response to DNA damage stimulus;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process","K08864//tousled-like kinase [EC:2.7.11.1]","AAH44925.2//TLK2 protein, partial [Homo sapiens];XP_016879534.1//PREDICTED: serine/threonine-protein kinase tousled-like 2 isoform X5 [Homo sapiens]","1//3;3//A2MP1"]
[147670,2542,2.61,2.21,-0.240003437178453,0.491111142077497,"*",0.338004,"SMIM17","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein;K12581//CCR4-NOT transcription complex subunit 7/8;K01064//wingless-type MMTV integration site family, member 9","XP_007996458.1//PREDICTED: small integral membrane protein 17 isoform X1 [Chlorocebus sabaeus]","1//3"]
[23155,4402,11.84,10.03,-0.239347475016769,0.0143223067385632,"*",0.00515456,"CLCC1","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0034707//chloride channel complex","GO:0005254//chloride channel activity","NA","K22188//chloride channel CLIC-like protein 1","NP_001265131.1//chloride channel CLIC-like protein 1 isoform 3 precursor [Homo sapiens];NP_001265132.1//chloride channel CLIC-like protein 1 isoform 4 precursor [Homo sapiens];NP_055942.1//chloride channel CLIC-like protein 1 isoform 2 precursor [Homo sapiens];NP_001041675.1//chloride channel CLIC-like protein 1 isoform 1 precursor [Homo sapiens]","1//3;4;2//1"]
[64081,2386,1.44,1.22,-0.239187663879426,0.345667803610108,"*",0.209794,"PBLD","GO:0070062//extracellular exosome;GO:0005737//cytoplasm","GO:0016853//isomerase activity;GO:0042802//identical protein binding;GO:0003824//catalytic activity","GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0010633//negative regulation of epithelial cell migration;GO:0060392//negative regulation of SMAD protein import into nucleus;GO:0009058//biosynthetic process;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0050680//negative regulation of epithelial cell proliferation;GO:0060394//negative regulation of pathway-restricted SMAD protein phosphorylation;GO:0030277//maintenance of gastrointestinal epithelium","K01368//cathepsin S [EC:3.4.22.27];K17985//activating molecule in BECN1-regulated autophagy protein 1","XP_007961461.1//PREDICTED: phenazine biosynthesis-like domain-containing protein isoform X2 [Chlorocebus sabaeus];NP_001028255.1//phenazine biosynthesis-like domain-containing protein isoform b [Homo sapiens]","1//3;3//A2MP1"]
[84946,1928,19.03,16.13,-0.238529123118379,0.0414086117753897,"*",0.017127,"LTV1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0034448//EGO complex;GO:0005829//cytosol;GO:0030688//preribosome, small subunit precursor;GO:0031902//late endosome membrane","NA","GO:0000056//ribosomal small subunit export from nucleus;GO:0042274//ribosomal small subunit biogenesis;GO:0006364//rRNA processing","K14798//protein LTV1","NP_116249.2//protein LTV1 homolog isoform 1 [Homo sapiens];NP_001316882.1//protein LTV1 homolog isoform 2 [Homo sapiens]","1//3;4"]
[79658,3073,3.88,3.29,-0.237969068451886,0.295537656016286,"*",0.1726714,"ARHGAP10","GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0048471//perinuclear region of cytoplasm","GO:0005096//GTPase activator activity","GO:0007165//signal transduction;GO:0007010//cytoskeleton organization;GO:0043066//negative regulation of apoptotic process;GO:0051056//regulation of small GTPase mediated signal transduction","K13736//Rho GTPase-activating protein 10","NP_078881.3//rho GTPase-activating protein 10 [Homo sapiens]","3//A2MP1"]
[23119,6812,1.45,1.23,-0.237394584675695,0.356051837345078,"*",0.217612,"HIC2","NA","GO:0003676//nucleic acid binding","NA","K09228//KRAB domain-containing zinc finger protein","XP_004063137.2//PREDICTED: hypermethylated in cancer 2 protein [Gorilla gorilla gorilla]","2//1"]
[9687,7622,2.71,2.3,-0.236658990409496,0.00972413257225959,"*",0.00334872,"GREB1","GO:0070062//extracellular exosome;GO:0016021//integral component of membrane","NA","NA","K10955//mucin-2","NP_149081.1//protein GREB1 isoform b [Homo sapiens];NP_055483.2//protein GREB1 isoform a [Homo sapiens];XP_016802839.1//PREDICTED: protein GREB1 isoform X8 [Pan troglodytes]","3//A2MP1;2//1"]
[83445,2391,1.92,1.63,-0.236234346490079,0.497068950602737,"*",0.343318,"GSG1","GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0070063//RNA polymerase binding","NA","K11167//dehydrogenase/reductase SDR family member 7C [EC:1.1.-.-];K11290//template-activating factor I","EAW96301.1//germ cell associated 1, isoform CRA_c [Homo sapiens];NP_001193774.1//germ cell-specific gene 1 protein isoform 7 [Homo sapiens];NP_001193772.1//germ cell-specific gene 1 protein isoform 6 [Homo sapiens];NP_722545.2//germ cell-specific gene 1 protein isoform 2 [Homo sapiens];NP_001193771.1//germ cell-specific gene 1 protein isoform 5 [Homo sapiens];NP_112579.2//germ cell-specific gene 1 protein isoform 1 [Homo sapiens];NP_001074024.1//germ cell-specific gene 1 protein isoform 4 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[9429,4292,16.16,13.73,-0.235095572604694,0.00223560663522538,"*",0.000670654,"ABCG2","GO:0005634//nucleus;GO:0016324//apical plasma membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0005886//plasma membrane;GO:0043235//receptor complex","GO:0015232//heme transporter activity;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0042626//ATPase activity, coupled to transmembrane movement of substances;GO:0008559//xenobiotic transmembrane transporting ATPase activity;GO:0042803//protein homodimerization activity;GO:0005215//transporter activity","GO:0006810//transport;GO:0006879//cellular iron ion homeostasis;GO:0042493//response to drug;GO:0033344//cholesterol efflux;GO:0046415//urate metabolic process","K05681//ATP-binding cassette, subfamily G (WHITE), member 2","NP_001335916.1//ATP-binding cassette sub-family G member 2 isoform 3 [Homo sapiens];NP_001244315.1//ATP-binding cassette sub-family G member 2 isoform 2 [Homo sapiens];NP_004818.2//ATP-binding cassette sub-family G member 2 isoform 1 [Homo sapiens]","1//3;2//1"]
[23463,4815,29.2,24.81,-0.235046633874949,{"v":2.18870512374582e-05,"d":"2.19E-05"},"*",{"v":4.50648e-06,"d":"4.51E-06"},"ICMT","GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0004671//protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity;GO:0003880//protein C-terminal carboxyl O-methyltransferase activity","GO:0043687//post-translational protein modification;GO:0006612//protein targeting to membrane;GO:0006464//cellular protein modification process;GO:0006481//C-terminal protein methylation","K00587//protein-S-isoprenylcysteine O-methyltransferase [EC:2.1.1.100]","NP_036537.1//protein-S-isoprenylcysteine O-methyltransferase [Homo sapiens]","3//A2MP1"]
[26577,2047,10.19,8.66,-0.234715121439089,0.154869309937508,"*",0.0791216,"PCOLCE2","GO:0070062//extracellular exosome","GO:0016504//peptidase activator activity;GO:0005518//collagen binding;GO:0008201//heparin binding","GO:1990830//cellular response to leukemia inhibitory factor","K14616//cubilin","NP_037495.1//procollagen C-endopeptidase enhancer 2 precursor [Homo sapiens]","3//A2MP1"]
[56658,3481,2.4,2.04,-0.234465253637023,0.428240891209417,"*",0.282402,"TRIM39","GO:0005829//cytosol;GO:0005622//intracellular;GO:0005739//mitochondrion","GO:0042802//identical protein binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0016874//ligase activity","GO:2001235//positive regulation of apoptotic signaling pathway;GO:0016567//protein ubiquitination;GO:2000059//negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0006915//apoptotic process","K12015//tripartite motif-containing protein 39 [EC:2.3.2.27]","NP_742013.1//E3 ubiquitin-protein ligase TRIM39 isoform 2 [Homo sapiens];NP_067076.2//E3 ubiquitin-protein ligase TRIM39 isoform 1 [Homo sapiens]","3//A2MP1;2//1"]
[9070,2874,14.11,12,-0.233683582101383,0.0305802136283186,"*",0.01211416,"ASH2L","GO:0048188//Set1C/COMPASS complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0071339//MLL1 complex;GO:0035097//histone methyltransferase complex;GO:0005719//nuclear euchromatin;GO:0044666//MLL3/4 complex","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0008168//methyltransferase activity;GO:0042800//histone methyltransferase activity (H3-K4 specific);GO:0044212//transcription regulatory region DNA binding;GO:1990188//euchromatin binding;GO:0018024//histone-lysine N-methyltransferase activity;GO:0008013//beta-catenin binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0051568//histone H3-K4 methylation;GO:0043627//response to estrogen;GO:0045652//regulation of megakaryocyte differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:1904837//beta-catenin-TCF complex assembly;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006974//cellular response to DNA damage stimulus;GO:0030097//hemopoiesis;GO:0008284//positive regulation of cell proliferation","K14964//Set1/Ash2 histone methyltransferase complex subunit ASH2","NP_004665.2//set1/Ash2 histone methyltransferase complex subunit ASH2 isoform a [Homo sapiens];XP_008954402.1//PREDICTED: set1/Ash2 histone methyltransferase complex subunit ASH2 isoform X2 [Pan paniscus];NP_001098684.1//set1/Ash2 histone methyltransferase complex subunit ASH2 isoform b [Homo sapiens];XP_003269625.1//PREDICTED: set1/Ash2 histone methyltransferase complex subunit ASH2 isoform X1 [Nomascus leucogenys]","4;1//3;2//1"]
[201780,2118,4.09,3.48,-0.23301353709302,0.407426983533943,"*",0.264876,"SLC10A4","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0008508//bile acid:sodium symporter activity","GO:0015721//bile acid and bile salt transport","K14344//solute carrier family 10 (sodium/bile acid cotransporter), member 4","NP_689892.1//sodium/bile acid cotransporter 4 [Homo sapiens]","3//A2MP1"]
[162239,3342,3.63,3.09,-0.232362710091376,0.226262762962963,"*",0.1246754,"ZFP1","GO:0005654//nucleoplasm;GO:0005813//centrosome","GO:0046872//metal ion binding;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","XP_013846339.1//zinc finger protein 182 isoform X3 [Sus scrofa];XP_008690954.1//PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 28 homolog [Ursus maritimus]","1//3;3//A2MP1"]
[51101,3352,2.56,2.18,-0.231815675223074,0.407387755054882,"*",0.264876,"ZC2HC1A","NA","GO:0046872//metal ion binding","NA","K00234//succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1]","NP_057094.2//zinc finger C2HC domain-containing protein 1A [Homo sapiens]","2//1"]
[26112,3416,3.17,2.7,-0.231523433088576,0.351657888980263,"*",0.214156,"CCDC69","GO:0051233//spindle midzone;GO:0005737//cytoplasm;GO:0030496//midbody","NA","GO:0051255//spindle midzone assembly","K17985//activating molecule in BECN1-regulated autophagy protein 1;K01064//wingless-type MMTV integration site family, member 9","NP_056436.2//coiled-coil domain-containing protein 69 [Homo sapiens]","2//1"]
[146664,4195,53.18,45.31,-0.231054286344278,{"v":1.56762256475584E-7,"d":"1.57E-07"},"*",{"v":2.3111e-08,"d":"2.31E-08"},"MGAT5B","GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0046872//metal ion binding;GO:0030144//alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity","GO:0006487//protein N-linked glycosylation","K09661//mannosyl alpha-1,6-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B [EC:2.4.1.-]","NP_653278.2//alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B isoform 1 [Homo sapiens];NP_001186101.1//alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B isoform 3 [Homo sapiens];NP_945193.1//alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B isoform 2 [Homo sapiens]","1//3;2//1"]
[5451,13905,1.96,1.67,-0.231005551641156,0.10786750448472,"*",0.0510436,"POU2F1","GO:0090575//RNA polymerase II transcription factor complex;GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005783//endoplasmic reticulum","GO:0003677//DNA binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0000983//transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0042795//snRNA transcription from RNA polymerase II promoter;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated","K09364//POU domain transcription factor, class 2","XP_011946498.1//PREDICTED: POU domain, class 2, transcription factor 1 isoform X1 [Cercocebus atys];XP_004425133.2//PREDICTED: POU domain, class 2, transcription factor 1 isoform X1 [Ceratotherium simum simum];XP_012513230.1//PREDICTED: POU domain, class 2, transcription factor 1 isoform X3 [Propithecus coquereli]","1//3;3//A2MP1"]
[7430,3138,82.53,70.34,-0.23057330541206,{"v":7.49911504771472e-09,"d":"7.50E-09"},"*",{"v":9.3469e-10,"d":"9.35E-10"},"EZR","GO:0005884//actin filament;GO:0016324//apical plasma membrane;GO:0015629//actin cytoskeleton;GO:0045177//apical part of cell","GO:0051015//actin filament binding;GO:0003779//actin binding;GO:0051117//ATPase binding;GO:0045296//cadherin binding","GO:0031532//actin cytoskeleton reorganization;GO:0051017//actin filament bundle assembly;GO:0030953//astral microtubule organization;GO:0007411//axon guidance","K08007//villin 2 (ezrin)","NP_003370.2//ezrin [Homo sapiens]","1//3;4"]
[57478,10698,2.66,2.27,-0.228733948210275,0.0936487628988643,"*",0.0433596,"USP31","GO:0005634//nucleus","GO:0004843//thiol-dependent ubiquitin-specific protease activity","GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination","K11852//ubiquitin carboxyl-terminal hydrolase 31 [EC:3.4.19.12]","NP_065769.3//ubiquitin carboxyl-terminal hydrolase 31 [Homo sapiens]","3//A2MP1"]
[2653,1538,36.29,30.97,-0.228700673804671,0.0146213646911867,"*",0.00527592,"GCSH","GO:0005759//mitochondrial matrix;GO:0005960//glycine cleavage complex;GO:0005739//mitochondrion","GO:0004047//aminomethyltransferase activity","GO:0019464//glycine decarboxylation via glycine cleavage system;GO:0006546//glycine catabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0009249//protein lipoylation","K02437//glycine cleavage system H protein","NP_004474.2//glycine cleavage system H protein, mitochondrial precursor [Homo sapiens]",4]
[23765,8592,3.01,2.57,-0.227995127565824,0.124173126121236,"*",0.0601432,"IL17RA","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0030368//interleukin-17 receptor activity;GO:0005102//receptor binding","GO:0050832//defense response to fungus;GO:0072537//fibroblast activation;GO:0032747//positive regulation of interleukin-23 production;GO:2000667//positive regulation of interleukin-13 secretion;GO:0071621//granulocyte chemotaxis;GO:0007166//cell surface receptor signaling pathway;GO:0097398//cellular response to interleukin-17;GO:2000664//positive regulation of interleukin-5 secretion;GO:1900017//positive regulation of cytokine production involved in inflammatory response","K05164//interleukin 17 receptor A","NP_055154.3//interleukin-17 receptor A isoform 1 precursor [Homo sapiens];NP_001276834.1//interleukin-17 receptor A isoform 2 precursor [Homo sapiens]","6;1//3"]
[65082,4069,13.97,11.93,-0.227737977714235,0.0522678848920863,"*",0.022286,"VPS33A","GO:0005765//lysosomal membrane;GO:0005770//late endosome;GO:0030136//clathrin-coated vesicle;GO:0031902//late endosome membrane;GO:0005764//lysosome;GO:0048471//perinuclear region of cytoplasm;GO:0030897//HOPS complex;GO:0005776//autophagosome;GO:0005769//early endosome;GO:0033263//CORVET complex","NA","GO:0035751//regulation of lysosomal lumen pH;GO:0006904//vesicle docking involved in exocytosis;GO:0016192//vesicle-mediated transport;GO:0032400//melanosome localization;GO:0048070//regulation of developmental pigmentation;GO:0043473//pigmentation;GO:0097352//autophagosome maturation;GO:0030220//platelet formation;GO:0008333//endosome to lysosome transport;GO:0032418//lysosome localization;GO:0015031//protein transport","K20182//vacuolar protein sorting-associated protein 33","XP_018894523.1//PREDICTED: vacuolar protein sorting-associated protein 33A isoform X2 [Gorilla gorilla gorilla];NP_001337950.1//vacuolar protein sorting-associated protein 33A isoform 5 [Homo sapiens];NP_001337947.1//vacuolar protein sorting-associated protein 33A isoform 2 [Homo sapiens];NP_075067.2//vacuolar protein sorting-associated protein 33A isoform 1 [Homo sapiens];NP_001337949.1//vacuolar protein sorting-associated protein 33A isoform 4 [Homo sapiens]","1//3;5"]
[153769,3043,3.43,2.93,-0.227307911750565,0.369891140695915,"*",0.22959,"SH3RF2","GO:0005654//nucleoplasm","GO:0004864//protein phosphatase inhibitor activity;GO:0046872//metal ion binding;GO:0019902//phosphatase binding;GO:0016740//transferase activity;GO:0008157//protein phosphatase 1 binding","GO:0016567//protein ubiquitination;GO:0010923//negative regulation of phosphatase activity","K12171//E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27]","NP_689763.3//putative E3 ubiquitin-protein ligase SH3RF2 [Homo sapiens]","3//A2MP1"]
[1389,3823,9.44,8.07,-0.226218186084061,0.0576746937744885,"*",0.0248802,"CREBL2","GO:0005634//nucleus","GO:0003677//DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0007165//signal transduction;GO:0030154//cell differentiation;GO:0045600//positive regulation of fat cell differentiation;GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046326//positive regulation of glucose import;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0007049//cell cycle;GO:0050821//protein stabilization;GO:0046889//positive regulation of lipid biosynthetic process","NA","XP_011239631.1//PREDICTED: cAMP-responsive element-binding protein-like 2 isoform X1 [Mus musculus]","3//A2MP1"]
[790,7013,30.45,26.04,-0.225712779628059,{"v":2.32273596688742e-07,"d":"2.32E-07"},"*",{"v":3.51304e-08,"d":"3.51E-08"},"CAD","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0042995//cell projection;GO:0016363//nuclear matrix;GO:0005737//cytoplasm;GO:0043195//terminal bouton;GO:0043025//neuronal cell body;GO:0005829//cytosol","GO:0004087//carbamoyl-phosphate synthase (ammonia) activity;GO:0016597//amino acid binding;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0004070//aspartate carbamoyltransferase activity;GO:0004088//carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity;GO:0070335//aspartate binding;GO:0046872//metal ion binding;GO:0016812//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides;GO:0004672//protein kinase activity;GO:0008270//zinc ion binding;GO:0004151//dihydroorotase activity;GO:0019899//enzyme binding","GO:0046134//pyrimidine nucleoside biosynthetic process;GO:0006526//arginine biosynthetic process;GO:0017144//drug metabolic process;GO:0046777//protein autophosphorylation;GO:0006541//glutamine metabolic process;GO:0018107//peptidyl-threonine phosphorylation;GO:0044205//'de novo' UMP biosynthetic process;GO:0000050//urea cycle;GO:0006207//'de novo' pyrimidine nucleobase biosynthetic process","K11540//carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:6.3.5.5 2.1.3.2 3.5.2.3]","NP_001293008.1//CAD protein isoform 2 [Homo sapiens];NP_004332.2//CAD protein isoform 1 [Homo sapiens]","4;1//3"]
[27072,4894,6.01,5.14,-0.225596631517307,0.0972265098777046,"*",0.04529,"VPS41","GO:0016020//membrane;GO:0005765//lysosomal membrane;GO:0010008//endosome membrane;GO:0005770//late endosome;GO:0015630//microtubule cytoskeleton;GO:0030136//clathrin-coated vesicle;GO:0031902//late endosome membrane;GO:0030897//HOPS complex;GO:0005829//cytosol;GO:0005798//Golgi-associated vesicle;GO:0030123//AP-3 adaptor complex;GO:0071439//clathrin complex;GO:0005769//early endosome;GO:0033263//CORVET complex","GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0051020//GTPase binding;GO:0043621//protein self-association;GO:0008017//microtubule binding","GO:0045055//regulated exocytosis;GO:0042144//vacuole fusion, non-autophagic;GO:0006886//intracellular protein transport;GO:0048193//Golgi vesicle transport;GO:0006623//protein targeting to vacuole;GO:0006914//autophagy;GO:0008333//endosome to lysosome transport;GO:1902774//late endosome to lysosome transport;GO:0034058//endosomal vesicle fusion;GO:0035542//regulation of SNARE complex assembly","K20184//vacuolar protein sorting-associated protein 41","NP_055211.2//vacuolar protein sorting-associated protein 41 homolog isoform 1 [Homo sapiens];NP_542198.2//vacuolar protein sorting-associated protein 41 homolog isoform 2 [Homo sapiens]","3//A2MP1"]
[125965,1679,7.34,6.28,-0.225015503951586,0.327767325882599,"*",0.196447,"COX6B2","GO:0005758//mitochondrial intermembrane space;GO:0030061//mitochondrial crista","NA","NA","K02267//cytochrome c oxidase subunit 6b","EAW72367.1//cytochrome c oxidase subunit VIb polypeptide 2 (testis), isoform CRA_a, partial [Homo sapiens]",4]
[79707,6728,9.65,8.26,-0.224387160735997,0.00781119991079725,"*",0.00263128,"NOL9","GO:0016020//membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0045111//intermediate filament cytoskeleton","GO:0003723//RNA binding;GO:0005524//ATP binding;GO:0051731//polynucleotide 5'-hydroxyl-kinase activity","GO:0000448//cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000460//maturation of 5.8S rRNA;GO:0006364//rRNA processing","K06947//polynucleotide 5'-hydroxyl-kinase GRC3/NOL9 [EC:2.7.1.-]","NP_078930.3//polynucleotide 5'-hydroxyl-kinase NOL9 [Homo sapiens]",4]
[9276,3142,29.3,25.09,-0.223788193900438,1.40311222802437E-3,"*",4.037E-4,"COPB2","GO:0030126//COPI vesicle coat;GO:0000139//Golgi membrane","GO:0005198//structural molecule activity","GO:0006886//intracellular protein transport;GO:1901998//toxin transport;GO:0006891//intra-Golgi vesicle-mediated transport","K17302//coatomer subunit beta'","EHH16722.1//hypothetical protein EGK_12054 [Macaca mulatta]","2//1"]
[54811,5607,3.91,3.35,-0.223007511962218,0.136459980969163,"*",0.0678712,"ZNF562","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","EHB03705.1//Zinc finger protein 26 [Heterocephalus glaber];XP_015296267.1//PREDICTED: zinc finger protein 266 [Macaca fascicularis]","1//3;3//A2MP1"]
[130951,2555,0.28,0.24,-0.222392421336448,0.873899676907426,"*",0.806664,"M1AP","GO:0016021//integral component of membrane;GO:0005737//cytoplasm","GO:0042802//identical protein binding","GO:0006396//RNA processing;GO:0007127//meiosis I;GO:0030154//cell differentiation;GO:0051308//male meiosis chromosome separation;GO:0031497//chromatin assembly;GO:0007283//spermatogenesis;GO:0007292//female gamete generation","K17985//activating molecule in BECN1-regulated autophagy protein 1","XP_009440876.2//PREDICTED: meiosis 1 arrest protein isoform X2 [Pan troglodytes];XP_016799370.1//PREDICTED: meiosis 1 arrest protein isoform X1 [Pan troglodytes];XP_006712009.1//PREDICTED: meiosis 1 arrest protein isoform X1 [Homo sapiens]","4;1//3"]
[139105,4017,0.84,0.72,-0.222392421336448,1.02216308556701,"*",0.993112,"BEND2","NA","NA","NA","K22069//LYR motif-containing protein 4;K12581//CCR4-NOT transcription complex subunit 7/8;K11447//histone demethylase [EC:1.14.11.-];K08857//NIMA (never in mitosis gene a)-related kinase 1/4/5 [EC:2.7.11.1];K01064//wingless-type MMTV integration site family, member 9;K04460//serine/threonine-protein phosphatase 5 [EC:3.1.3.16]","NP_001171696.1//BEN domain-containing protein 2 isoform 2 [Homo sapiens];NP_699177.2//BEN domain-containing protein 2 isoform 1 [Homo sapiens]","1//3;4"]
[3683,4974,0.35,0.3,-0.222392421336448,0.749413224336251,"*",0.6485,"ITGAL","GO:0016020//membrane;GO:0008305//integrin complex;GO:0070062//extracellular exosome;GO:0034687//integrin alphaL-beta2 complex;GO:0009986//cell surface;GO:0035579//specific granule membrane;GO:0005886//plasma membrane","GO:0046872//metal ion binding;GO:0050839//cell adhesion molecule binding;GO:0046982//protein heterodimerization activity;GO:0032403//protein complex binding;GO:0030369//ICAM-3 receptor activity","GO:0043113//receptor clustering;GO:0007165//signal transduction;GO:0007159//leukocyte cell-cell adhesion;GO:0050900//leukocyte migration;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0006954//inflammatory response;GO:0002291//T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell;GO:0007160//cell-matrix adhesion;GO:0006928//movement of cell or subcellular component;GO:0007155//cell adhesion;GO:0030198//extracellular matrix organization;GO:0043312//neutrophil degranulation;GO:0007229//integrin-mediated signaling pathway;GO:0050776//regulation of immune response;GO:0006909//phagocytosis","K05718//integrin alpha L","NP_002200.2//integrin alpha-L isoform a precursor [Homo sapiens]","1//3;2//1"]
[4862,4004,54.95,47.14,-0.221167722586426,{"v":3.83958392112676e-07,"d":"3.84E-07"},"*",{"v":5.97306e-08,"d":"5.97E-08"},"NPAS2","NA","NA","NA","K09026//neuronal PAS domain-containing protein 2","XP_008006376.1//PREDICTED: neuronal PAS domain-containing protein 2 isoform X1 [Chlorocebus sabaeus]","3//A2MP1"]
[55646,1584,14.93,12.81,-0.220943689792895,0.0527666813141684,"*",0.0225218,"LYAR","GO:0005634//nucleus;GO:0005730//nucleolus","GO:0003723//RNA binding;GO:0046872//metal ion binding","NA","K15263//cell growth-regulating nucleolar protein","NP_060286.1//cell growth-regulating nucleolar protein [Homo sapiens]","1//3;2//1"]
[81609,6405,9.53,8.18,-0.220375370968193,0.00775547208333333,"*",0.00261008,"SNX27","GO:0005768//endosome;GO:0030904//retromer complex;GO:0005654//nucleoplasm;GO:0031901//early endosome membrane;GO:0005829//cytosol;GO:0005622//intracellular;GO:0071203//WASH complex;GO:0001772//immunological synapse;GO:0005769//early endosome","GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0035091//phosphatidylinositol binding","GO:0006886//intracellular protein transport;GO:0016197//endosomal transport;GO:0007165//signal transduction;GO:1990126//retrograde transport, endosome to plasma membrane;GO:0001770//establishment of natural killer cell polarity;GO:0008333//endosome to lysosome transport","K17936//sorting nexin-27","NP_001317652.1//sorting nexin-27 isoform 1 [Homo sapiens];NP_112180.4//sorting nexin-27 isoform 2 [Homo sapiens]","1//3;5"]
[819,2255,11.4,9.79,-0.219653059448409,0.128422144506898,"*",0.0629328,"CAMLG","GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane","GO:0050839//cell adhesion molecule binding","GO:0001881//receptor recycling;GO:0007165//signal transduction;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0006952//defense response;GO:0016032//viral process","K09228//KRAB domain-containing zinc finger protein;K01368//cathepsin S [EC:3.4.22.27];K01064//wingless-type MMTV integration site family, member 9;K09488//TNF receptor-associated protein 1","XP_007107121.1//PREDICTED: calcium signal-modulating cyclophilin ligand isoform X1 [Physeter catodon]","3//A2MP1"]
[90226,1546,5.6,4.81,-0.219389933174924,0.441828053613272,"*",0.295096,"UCN2","NA","NA","NA","K05257//urocortin 2/3","XP_007982322.1//PREDICTED: urocortin-2 [Chlorocebus sabaeus]","3//A2MP1"]
[64769,4784,7.83,6.73,-0.218405802680723,0.0642663188322839,"*",0.028114,"MEAF6","GO:0035267//NuA4 histone acetyltransferase complex;GO:0005654//nucleoplasm;GO:0070776//MOZ/MORF histone acetyltransferase complex;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0016604//nuclear body;GO:0000777//condensed chromosome kinetochore;GO:0000776//kinetochore;GO:0000123//histone acetyltransferase complex","NA","GO:0006355//regulation of transcription, DNA-templated;GO:0043981//histone H4-K5 acetylation;GO:0043968//histone H2A acetylation;GO:0016573//histone acetylation;GO:0006351//transcription, DNA-templated;GO:0044154//histone H3-K14 acetylation;GO:1901796//regulation of signal transduction by p53 class mediator;GO:0043982//histone H4-K8 acetylation;GO:0043983//histone H4-K12 acetylation","K11344//chromatin modification-related protein EAF6","NP_001230385.1//chromatin modification-related protein MEAF6 [Sus scrofa];NP_073593.2//chromatin modification-related protein MEAF6 isoform 1 [Homo sapiens];XP_005204892.1//PREDICTED: chromatin modification-related protein MEAF6 isoform X2 [Bos taurus]","1//3;5"]
[81887,2434,36.13,31.06,-0.218139425045142,0.0025417163848854,"*",0.000770598,"LAS1L","GO:0016020//membrane;GO:0005654//nucleoplasm;GO:0071339//MLL1 complex;GO:0005730//nucleolus;GO:0030687//preribosome, large subunit precursor;GO:0005737//cytoplasm","GO:0003723//RNA binding","GO:0000470//maturation of LSU-rRNA;GO:0000460//maturation of 5.8S rRNA;GO:0006325//chromatin organization;GO:0006364//rRNA processing;GO:0000478//endonucleolytic cleavage involved in rRNA processing","K16912//ribosomal biogenesis protein LAS1","NP_001164120.1//ribosomal biogenesis protein LAS1L isoform 2 [Homo sapiens];XP_011529347.1//PREDICTED: ribosomal biogenesis protein LAS1L isoform X3 [Homo sapiens];NP_112483.1//ribosomal biogenesis protein LAS1L isoform 1 [Homo sapiens]","4;1//3"]
[286205,12187,2.57,2.21,-0.217721989802446,0.0984286536572272,"*",0.0459116,"SCAI","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0016021//integral component of membrane;GO:0005737//cytoplasm","GO:0003714//transcription corepressor activity","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0030336//negative regulation of cell migration;GO:0035024//negative regulation of Rho protein signal transduction","K11447//histone demethylase [EC:1.14.11.-]","NP_775961.2//protein SCAI isoform 1 [Homo sapiens];XP_017911250.1//PREDICTED: protein SCAI isoform X1 [Capra hircus]","4;2//1"]
[9991,6564,26.28,22.61,-0.217004283570801,{"v":4.18702699322799e-18,"d":"4.19E-18"},"*",{"v":2.32234e-19,"d":"2.32E-19"},"PTBP3","GO:0005634//nucleus","GO:0003723//RNA binding","GO:0006397//mRNA processing;GO:0033119//negative regulation of RNA splicing;GO:0009653//anatomical structure morphogenesis;GO:0043249//erythrocyte maturation;GO:0008380//RNA splicing;GO:0045595//regulation of cell differentiation","K17844//polypyrimidine tract-binding protein 3","XP_019309725.1//PREDICTED: polypyrimidine tract-binding protein 3 isoform X2 [Panthera pardus];NP_001231827.1//polypyrimidine tract-binding protein 3 isoform 6 [Homo sapiens];NP_001231825.1//polypyrimidine tract-binding protein 3 isoform 4 [Homo sapiens];AAH39896.1//Similar to ROD1 regulator of differentiation 1 (S. pombe), partial [Homo sapiens];XP_019309724.1//PREDICTED: polypyrimidine tract-binding protein 3 isoform X1 [Panthera pardus]","6;1//3;2//1"]
[57107,3568,5.39,4.64,-0.216160467624933,0.210880127816412,"*",0.1139022,"PDSS2","GO:0005759//mitochondrial matrix;GO:1990234//transferase complex;GO:0005829//cytosol;GO:0005739//mitochondrion","GO:0046982//protein heterodimerization activity;GO:0050347//trans-octaprenyltranstransferase activity;GO:0000010//trans-hexaprenyltranstransferase activity","GO:0008299//isoprenoid biosynthetic process;GO:0050878//regulation of body fluid levels;GO:0006744//ubiquinone biosynthetic process;GO:0051290//protein heterotetramerization","K12505//decaprenyl-diphosphate synthase subunit 2 [EC:2.5.1.91]","NP_065114.3//decaprenyl-diphosphate synthase subunit 2 [Homo sapiens]","3//A2MP1"]
[388759,2258,2.16,1.86,-0.215728691055437,0.560829824798544,"*",0.405192,"C1orf229","NA","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K16506//protocadherin Fat 1/2/3;K07560//D-tyrosyl-tRNA(Tyr) deacylase [EC:3.1.-.-];K04487//cysteine desulfurase [EC:2.8.1.7]","NP_997284.1//putative uncharacterized protein C1orf229 [Homo sapiens]","2//1"]
[10795,5700,1.37,1.18,-0.215389033598686,0.386045775958466,"*",0.242058,"ZNF268","GO:0005634//nucleus;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0007346//regulation of mitotic cell cycle;GO:0046022//positive regulation of transcription from RNA polymerase II promoter during mitotic cell cycle;GO:0030335//positive regulation of cell migration;GO:0006355//regulation of transcription, DNA-templated;GO:0008588//release of cytoplasmic sequestered NF-kappaB;GO:0071356//cellular response to tumor necrosis factor;GO:0043497//regulation of protein heterodimerization activity;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0043065//positive regulation of apoptotic process;GO:0090073//positive regulation of protein homodimerization activity;GO:0001934//positive regulation of protein phosphorylation;GO:0071157//negative regulation of cell cycle arrest;GO:0045597//positive regulation of cell differentiation;GO:0008285//negative regulation of cell proliferation;GO:0030154//cell differentiation;GO:0006351//transcription, DNA-templated;GO:0043066//negative regulation of apoptotic process;GO:0045732//positive regulation of protein catabolic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0008284//positive regulation of cell proliferation","K09228//KRAB domain-containing zinc finger protein","NP_003406.1//zinc finger protein 268 isoform a [Homo sapiens]","1//3;2//1"]
[6386,2170,74.63,64.29,-0.215161335387994,{"v":3.02397233165532e-05,"d":"3.02E-05"},"*",{"v":6.39286E-6,"d":"6.39E-06"},"SDCBP","GO:0016020//membrane;GO:0005615//extracellular space;GO:0042470//melanosome;GO:0005737//cytoplasm;GO:0005895//interleukin-5 receptor complex;GO:0035578//azurophil granule lumen;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005856//cytoskeleton;GO:0070062//extracellular exosome;GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0072562//blood microparticle;GO:0005925//focal adhesion;GO:0005622//intracellular;GO:0005912//adherens junction;GO:1903561//extracellular vesicle;GO:0045121//membrane raft;GO:0005789//endoplasmic reticulum membrane","GO:0050839//cell adhesion molecule binding;GO:0005137//interleukin-5 receptor binding;GO:0042043//neurexin family protein binding;GO:0045545//syndecan binding;GO:0047485//protein N-terminus binding;GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity;GO:0019838//growth factor binding;GO:0042803//protein homodimerization activity;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0008093//cytoskeletal adaptor activity;GO:0005109//frizzled binding;GO:0045296//cadherin binding;GO:0008022//protein C-terminus binding;GO:0046875//ephrin receptor binding","GO:0046330//positive regulation of JNK cascade;GO:1903543//positive regulation of exosomal secretion;GO:0007346//regulation of mitotic cell cycle;GO:0030335//positive regulation of cell migration;GO:0030307//positive regulation of cell growth;GO:0035556//intracellular signal transduction;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0043312//neutrophil degranulation;GO:0006612//protein targeting to membrane;GO:0030036//actin cytoskeleton organization;GO:0048013//ephrin receptor signaling pathway;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0042327//positive regulation of phosphorylation;GO:0007268//chemical synaptic transmission;GO:0007265//Ras protein signal transduction;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0002091//negative regulation of receptor internalization;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0006930//substrate-dependent cell migration, cell extension;GO:0008284//positive regulation of cell proliferation;GO:1903553//positive regulation of extracellular exosome assembly","K17254//syntenin-1","NP_001335269.1//syntenin-1 isoform 6 [Homo sapiens];NP_001335270.1//syntenin-1 isoform 7 [Homo sapiens];NP_001335268.1//syntenin-1 isoform 5 [Homo sapiens];NP_001317466.1//syntenin-1 isoform 4 [Homo sapiens]","1//3;3//A2MP1"]
[10794,3602,0.29,0.25,-0.214124805352847,0.794388124453224,"*",0.704874,"ZNF460","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_012414047.1//PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 91-like [Trichechus manatus latirostris]","1//3;3//A2MP1"]
[404636,2473,23.37,20.15,-0.213877895367496,0.0206263976333721,"*",0.00776944,"FAM45A","NA","NA","NA","NA","NP_996892.1//protein FAM45A isoform 1 [Homo sapiens];NP_001290040.1//protein FAM45A isoform 2 [Homo sapiens];NP_001290041.1//protein FAM45A isoform 3 [Homo sapiens];XP_012594603.1//protein FAM45A isoform X4 [Microcebus murinus]","1//3;3//A2MP1"]
[401207,5680,1.82,1.57,-0.213173891307069,0.486791002827693,"*",0.334086,"C5orf63","NA","NA","GO:0055114//oxidation-reduction process","K00626//acetyl-CoA C-acetyltransferase [EC:2.3.1.9]","XP_011945500.1//PREDICTED: glutaredoxin-like protein C5orf63 homolog isoform X1 [Cercocebus atys];XP_008950280.1//PREDICTED: glutaredoxin-like protein C5orf63 homolog isoform X1 [Pan paniscus]","1//3"]
[119385,3155,0.73,0.63,-0.212544635380101,0.624836251014674,"*",0.501152,"AGAP11","NA","NA","NA","K12491//Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1/3","XP_009234323.1//PREDICTED: LOW QUALITY PROTEIN: arf-GAP with GTPase, ANK repeat and PH domain-containing protein 11-like [Pongo abelii]","1//3"]
[9213,8096,9.54,8.24,-0.211344928822293,0.000799479397172823,"*",2.19514E-4,"XPR1","GO:0031226//intrinsic component of plasma membrane;GO:0016021//integral component of membrane;GO:0005737//cytoplasm","GO:0015114//phosphate ion transmembrane transporter activity;GO:0015562//efflux transmembrane transporter activity;GO:0004872//receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0000822//inositol hexakisphosphate binding;GO:0001618//virus receptor activity;GO:0004930//G-protein coupled receptor activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0030643//cellular phosphate ion homeostasis;GO:0035435//phosphate ion transmembrane transport;GO:0009615//response to virus","K10352//myosin heavy chain;K06245//laminin, beta 4;K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K02927//large subunit ribosomal protein L40e;K01064//wingless-type MMTV integration site family, member 9;K12025//tripartite motif-containing protein 52","NP_001129141.1//xenotropic and polytropic retrovirus receptor 1 isoform 2 [Homo sapiens];XP_009238733.1//PREDICTED: xenotropic and polytropic retrovirus receptor 1 [Pongo abelii]","1//3;3//A2MP1"]
[152002,2505,11.34,9.8,-0.210566985939658,0.182716958931553,"*",0.0959224,"XXYLT1","GO:0030176//integral component of endoplasmic reticulum membrane","GO:0035252//UDP-xylosyltransferase activity;GO:0000287//magnesium ion binding;GO:0016757//transferase activity, transferring glycosyl groups;GO:0030145//manganese ion binding","GO:0016266//O-glycan processing","K17455//fascin 1/2;K12489//Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein;K21125//mucin-5AC;K09291//nucleoprotein TPR;K09668//glycosyltransferase-like protein LARGE [EC:2.4.2.- 2.4.1.-]","NP_689744.3//xyloside xylosyltransferase 1 isoform 1 [Homo sapiens];NP_001294998.1//xyloside xylosyltransferase 1 isoform 2 [Homo sapiens]","4;1//3"]
[6509,4189,7.01,6.06,-0.210096650537672,0.092203122156013,"*",0.042621,"SLC1A4","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0030425//dendrite;GO:0042470//melanosome;GO:0005882//intermediate filament;GO:0043025//neuronal cell body;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0015193//L-proline transmembrane transporter activity;GO:0034590//L-hydroxyproline transmembrane transporter activity;GO:0015293//symporter activity;GO:0015186//L-glutamine transmembrane transporter activity;GO:0015195//L-threonine transmembrane transporter activity;GO:0005254//chloride channel activity;GO:0015180//L-alanine transmembrane transporter activity;GO:0015194//L-serine transmembrane transporter activity;GO:0015184//L-cystine transmembrane transporter activity;GO:0015171//amino acid transmembrane transporter activity","GO:0015826//threonine transport;GO:0006868//glutamine transport;GO:0015808//L-alanine transport;GO:0015824//proline transport;GO:0050890//cognition;GO:0015825//L-serine transport;GO:0006865//amino acid transport;GO:0035249//synaptic transmission, glutamatergic;GO:0034589//hydroxyproline transport;GO:0015811//L-cystine transport","K05615//solute carrier family 1 (glutamate/neutral amino acid transporter), member 4","AAA19438.1//neutral amino acid transporter [Homo sapiens];NP_003029.2//neutral amino acid transporter A isoform 1 [Homo sapiens];XP_004369325.1//PREDICTED: neutral amino acid transporter A isoform X2 [Trichechus manatus latirostris]","1//3;4"]
[54557,5453,4.44,3.84,-0.20945336562895,0.161089729010239,"*",0.0827332,"SGTB","NA","NA","NA","K16365//small glutamine-rich tetratricopeptide repeat-containing protein alpha","NP_061945.1//small glutamine-rich tetratricopeptide repeat-containing protein beta [Homo sapiens]","2//1"]
[23093,4773,8.24,7.13,-0.20874226073933,0.0680332523741825,"*",0.0299578,"TTLL5","GO:0005929//cilium;GO:0005634//nucleus;GO:0005874//microtubule;GO:0005829//cytosol;GO:0005813//centrosome;GO:0005886//plasma membrane","GO:0070740//tubulin-glutamic acid ligase activity;GO:0005524//ATP binding","GO:0060041//retina development in camera-type eye;GO:0018095//protein polyglutamylation;GO:0009566//fertilization;GO:0007288//sperm axoneme assembly;GO:0006351//transcription, DNA-templated","K16602//tubulin polyglutamylase TTLL5 [EC:6.-.-.-]","NP_055887.3//tubulin polyglutamylase TTLL5 [Homo sapiens]",4]
[6310,10596,1.04,0.9,-0.208586621811417,0.392314571513885,"*",0.24675,"ATXN1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0016363//nuclear matrix;GO:0042405//nuclear inclusion body;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0008022//protein C-terminus binding;GO:0008266//poly(U) RNA binding;GO:0042802//identical protein binding;GO:0034046//poly(G) binding;GO:0043621//protein self-association","GO:0006396//RNA processing;GO:0045892//negative regulation of transcription, DNA-templated;GO:0051168//nuclear export;GO:0006351//transcription, DNA-templated","K11432//histone-lysine N-methyltransferase PRDM2 [EC:2.1.1.43];K21125//mucin-5AC","NP_000323.2//ataxin-1 [Homo sapiens]","1//3;3//A2MP1"]
[5414,1814,0.67,0.58,-0.208108195330201,0.91107235664709,"*",0.854608,"2019-09-04","GO:0097227//sperm annulus;GO:0031105//septin complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0043209//myelin sheath;GO:0005739//mitochondrion","GO:0000287//magnesium ion binding;GO:0005198//structural molecule activity;GO:0005525//GTP binding;GO:0042803//protein homodimerization activity;GO:0003924//GTPase activity","GO:0030382//sperm mitochondrion organization;GO:0031398//positive regulation of protein ubiquitination;GO:0051260//protein homooligomerization;GO:0007420//brain development;GO:0006915//apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway;GO:0051301//cell division;GO:0048240//sperm capacitation;GO:0007049//cell cycle;GO:0042981//regulation of apoptotic process","K16943//septin 4","NP_001185642.1//septin-4 isoform 4 [Homo sapiens];NP_536340.1//septin-4 isoform 2 [Homo sapiens];NP_001243711.1//septin-4 isoform 5 [Homo sapiens];NP_004565.1//septin-4 isoform 1 [Homo sapiens];XP_006722012.1//PREDICTED: septin-4 isoform X1 [Homo sapiens];XP_011731354.1//PREDICTED: uncharacterized protein LOC105476826 isoform X1 [Macaca nemestrina]","4;1//3;3//A2MP1"]
[55171,2725,9.62,8.33,-0.207720398404494,0.145084684392488,"*",0.0730328,"TBCCD1","GO:0031616//spindle pole centrosome;GO:0005737//cytoplasm","NA","GO:0051661//maintenance of centrosome location;GO:0030334//regulation of cell migration;GO:0051684//maintenance of Golgi location;GO:0008360//regulation of cell shape","K16810//TBCC domain-containing protein 1","NP_001273678.1//TBCC domain-containing protein 1 isoform b [Homo sapiens];NP_060608.1//TBCC domain-containing protein 1 isoform a [Homo sapiens]","4;1//3"]
[93487,6469,25.41,22.01,-0.207237230161797,{"v":4.93155135067162e-05,"d":"4.93E-05"},"*",{"v":1.080224e-05,"d":"1.08E-05"},"MAPK1IP1L","NA","GO:0016301//kinase activity","NA","K10955//mucin-2;K06831//galectin-3","XP_011535664.2//PREDICTED: MAPK-interacting and spindle-stabilizing protein-like isoform X1 [Homo sapiens]","3//A2MP1"]
[3987,4398,18.14,15.72,-0.206573238269916,0.00611925675285171,"*",2.01498E-3,"LIMS1","GO:0005925//focal adhesion;GO:0043234//protein complex;GO:0005829//cytosol;GO:0005911//cell-cell junction;GO:0005886//plasma membrane;GO:0048471//perinuclear region of cytoplasm","GO:0046872//metal ion binding;GO:0008270//zinc ion binding;GO:0019901//protein kinase binding","GO:0051291//protein heterooligomerization;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045184//establishment of protein localization;GO:0034329//cell junction assembly;GO:0051894//positive regulation of focal adhesion assembly;GO:0007569//cell aging;GO:0043547//positive regulation of GTPase activity;GO:0010628//positive regulation of gene expression;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:0045216//cell-cell junction organization;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0010811//positive regulation of cell-substrate adhesion","K05760//paxillin","XP_005340991.1//LIM and senescent cell antigen-like-containing domain protein 1 isoform X4 [Ictidomys tridecemlineatus];NP_001180412.1//LIM and senescent cell antigen-like-containing domain protein 1 isoform d [Homo sapiens];XP_012593079.1//LIM and senescent cell antigen-like-containing domain protein 1 isoform X4 [Microcebus murinus];NP_001180414.1//LIM and senescent cell antigen-like-containing domain protein 1 isoform a [Homo sapiens];NP_001180411.1//LIM and senescent cell antigen-like-containing domain protein 1 isoform c [Homo sapiens]","1//3;2//1;5"]
[375323,4895,0.15,0.13,-0.206450877467426,0.882274897744158,"*",0.817764,"LHFPL4","GO:0016021//integral component of membrane","NA","NA","K03006//DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6];K18631//tektin-4","XP_019839659.1//PREDICTED: lipoma HMGIC fusion partner-like 4 protein [Bos indicus]","2//1"]
[91893,3081,1.73,1.5,-0.205809537140844,0.63751046814864,"*",0.481146,"FDXACB1","GO:0009328//phenylalanine-tRNA ligase complex","GO:0004826//phenylalanine-tRNA ligase activity","GO:0006432//phenylalanyl-tRNA aminoacylation","K03846//alpha-1,2-mannosyltransferase [EC:2.4.1.259 2.4.1.261]","NP_612387.1//ferredoxin-fold anticodon-binding domain-containing protein 1 [Homo sapiens]","2//1"]
[54733,3184,14.51,12.59,-0.204769236347728,0.0534272748681898,"*",0.0228372,"SLC35F2","GO:0016021//integral component of membrane","NA","GO:0006810//transport","K15287//solute carrier family 35, member F1/2","NP_059985.2//solute carrier family 35 member F2 [Homo sapiens]",4]
[3609,4984,77.24,67.02,-0.204756477746179,{"v":4.25758854640981e-10,"d":"4.26E-10"},"*",{"v":4.5657e-11,"d":"4.57E-11"},"ILF3","GO:0016020//membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0030529//intracellular ribonucleoprotein complex;GO:0005576//extracellular region;GO:0005739//mitochondrion","GO:0003723//RNA binding;GO:0003677//DNA binding;GO:0003725//double-stranded RNA binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0017148//negative regulation of translation;GO:0045071//negative regulation of viral genome replication;GO:0006468//protein phosphorylation;GO:0051607//defense response to virus;GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated","K13090//interleukin enhancer-binding factor 3","NP_060090.2//interleukin enhancer-binding factor 3 isoform d [Homo sapiens];NP_036350.2//interleukin enhancer-binding factor 3 isoform a [Homo sapiens];NP_001131145.1//interleukin enhancer-binding factor 3 isoform e [Homo sapiens];XP_011728190.1//PREDICTED: interleukin enhancer-binding factor 3 isoform X3 [Macaca nemestrina];NP_004507.2//interleukin enhancer-binding factor 3 isoform b [Homo sapiens]","1//3;3//A2MP1;2//1"]
[10291,5159,32.8,28.47,-0.20425332176318,{"v":4.94114466038275e-05,"d":"4.94E-05"},"*",{"v":1.082944e-05,"d":"1.08E-05"},"SF3A1","GO:0005684//U2-type spliceosomal complex;GO:0071004//U2-type prespliceosome;GO:0005654//nucleoplasm;GO:0005686//U2 snRNP;GO:0005681//spliceosomal complex;GO:0016607//nuclear speck;GO:0071013//catalytic step 2 spliceosome","GO:0003723//RNA binding","GO:0006396//RNA processing;GO:0006397//mRNA processing;GO:0000398//mRNA splicing, via spliceosome;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0000389//mRNA 3'-splice site recognition","K12825//splicing factor 3A subunit 1","NP_005868.1//splicing factor 3A subunit 1 [Homo sapiens]",5]
[26015,4709,6.69,5.81,-0.203468047236932,0.124275614627213,"*",0.0602084,"RPAP1","GO:0005634//nucleus","GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0003677//DNA binding","GO:0006366//transcription from RNA polymerase II promoter","K20826//RNA polymerase II-associated protein 1","NP_056355.2//RNA polymerase II-associated protein 1 [Homo sapiens]","3//A2MP1"]
[1718,4286,31.94,27.74,-0.20339652508763,0.000320628328557312,"*",{"v":8.1251e-05,"d":"8.13E-05"},"DHCR24","GO:0016020//membrane;GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0000139//Golgi membrane;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0016614//oxidoreductase activity, acting on CH-OH group of donors;GO:0050614//delta24-sterol reductase activity;GO:0000246//delta24(24-1) sterol reductase activity;GO:0042605//peptide antigen binding;GO:0016628//oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;GO:0050660//flavin adenine dinucleotide binding;GO:0019899//enzyme binding","GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0042987//amyloid precursor protein catabolic process;GO:0043588//skin development;GO:0009888//tissue development;GO:0055114//oxidation-reduction process;GO:0007050//cell cycle arrest;GO:0008202//steroid metabolic process;GO:0030539//male genitalia development;GO:0008285//negative regulation of cell proliferation;GO:0033489//cholesterol biosynthetic process via desmosterol;GO:0006695//cholesterol biosynthetic process;GO:0043066//negative regulation of apoptotic process;GO:0006915//apoptotic process;GO:0061024//membrane organization;GO:0031639//plasminogen activation;GO:0006979//response to oxidative stress;GO:0033490//cholesterol biosynthetic process via lathosterol;GO:0009725//response to hormone;GO:0008104//protein localization;GO:0007265//Ras protein signal transduction;GO:1901214//regulation of neuron death","K09828//Delta24-sterol reductase [EC:1.3.1.72 1.3.1.-]","XP_007976807.1//PREDICTED: delta(24)-sterol reductase [Chlorocebus sabaeus]","3//A2MP1"]
[8915,3114,6.66,5.79,-0.201958829082026,0.230645475858971,"*",0.128592,"BCL10","GO:0042101//T cell receptor complex;GO:0005634//nucleus;GO:0005881//cytoplasmic microtubule;GO:0005764//lysosome;GO:0046696//lipopolysaccharide receptor complex;GO:0001772//immunological synapse;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0045121//membrane raft;GO:0043234//protein complex;GO:0005829//cytosol;GO:0032449//CBM complex;GO:0005886//plasma membrane","GO:0043422//protein kinase B binding;GO:0002020//protease binding;GO:0019209//kinase activator activity;GO:0042802//identical protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0043621//protein self-association;GO:0019901//protein kinase binding;GO:0051059//NF-kappaB binding;GO:0008022//protein C-terminus binding;GO:0003713//transcription coactivator activity;GO:0019900//kinase binding;GO:0008134//transcription factor binding;GO:0019899//enzyme binding","GO:0016064//immunoglobulin mediated immune response;GO:0071260//cellular response to mechanical stimulus;GO:0051260//protein homooligomerization;GO:0042109//lymphotoxin A biosynthetic process;GO:0043065//positive regulation of apoptotic process;GO:0070231//T cell apoptotic process;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:0002906//negative regulation of mature B cell apoptotic process;GO:0045087//innate immune response;GO:0051259//protein oligomerization;GO:0001783//B cell apoptotic process;GO:0006915//apoptotic process;GO:0002250//adaptive immune response;GO:0042226//interleukin-6 biosynthetic process;GO:0042327//positive regulation of phosphorylation;GO:0001843//neural tube closure;GO:0009620//response to fungus;GO:0016567//protein ubiquitination;GO:0032094//response to food;GO:0002237//response to molecule of bacterial origin;GO:0045893//positive regulation of transcription, DNA-templated;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0051291//protein heterooligomerization;GO:0050852//T cell receptor signaling pathway;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0031398//positive regulation of protein ubiquitination;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0008219//cell death;GO:0002224//toll-like receptor signaling pathway;GO:0006968//cellular defense response;GO:0050870//positive regulation of T cell activation;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0050856//regulation of T cell receptor signaling pathway;GO:0032765//positive regulation of mast cell cytokine production;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0042981//regulation of apoptotic process;GO:0045416//positive regulation of interleukin-8 biosynthetic process","K07368//B-cell CLL/lymphoma 10","XP_003892185.1//B-cell lymphoma/leukemia 10 [Papio anubis]","4;1//3"]
[9832,8995,0.23,0.2,-0.201633861169651,0.690087883852478,"*",0.572798,"JAKMIP2","GO:0005794//Golgi apparatus","GO:0016301//kinase activity;GO:0019900//kinase binding;GO:0008017//microtubule binding","NA","K20478//golgin subfamily B member 1","NP_001257863.1//janus kinase and microtubule-interacting protein 2 isoform 2 [Homo sapiens];NP_001269211.1//janus kinase and microtubule-interacting protein 2 isoform 4 [Homo sapiens];XP_012880965.1//PREDICTED: janus kinase and microtubule-interacting protein 2 isoform X1 [Dipodomys ordii];NP_001257870.1//janus kinase and microtubule-interacting protein 2 isoform 1 [Homo sapiens]","1//3;4"]
[145748,2670,2.76,2.4,-0.20163386116965,0.355801209836066,"*",0.217392,"LYSMD4","GO:0016021//integral component of membrane","NA","NA","NA","NP_001271348.1//lysM and putative peptidoglycan-binding domain-containing protein 4 isoform c [Homo sapiens];NP_689662.2//lysM and putative peptidoglycan-binding domain-containing protein 4 isoform a [Homo sapiens];NP_001271347.1//lysM and putative peptidoglycan-binding domain-containing protein 4 isoform b [Homo sapiens];NP_001271349.1//lysM and putative peptidoglycan-binding domain-containing protein 4 isoform d [Homo sapiens];XP_016877416.1//PREDICTED: lysM and putative peptidoglycan-binding domain-containing protein 4 isoform X5 [Homo sapiens]","1//3;3//A2MP1"]
[2774,5661,8.18,7.12,-0.200223601975351,0.0388045998534127,"*",0.01590906,"GNAL","GO:0070062//extracellular exosome;GO:0005834//heterotrimeric G-protein complex;GO:0005886//plasma membrane","GO:0031683//G-protein beta/gamma-subunit complex binding;GO:0046872//metal ion binding;GO:0001664//G-protein coupled receptor binding;GO:0004871//signal transducer activity;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0007165//signal transduction;GO:0007190//activation of adenylate cyclase activity;GO:0001975//response to amphetamine;GO:0031000//response to caffeine;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0007191//adenylate cyclase-activating dopamine receptor signaling pathway","K04633//guanine nucleotide-binding protein G(olf) subunit alpha","NP_001135811.1//guanine nucleotide-binding protein G(olf) subunit alpha isoform 2 [Homo sapiens];XP_013369712.1//PREDICTED: guanine nucleotide-binding protein G(olf) subunit alpha isoform X1 [Chinchilla lanigera];NP_892023.1//guanine nucleotide-binding protein G(olf) subunit alpha isoform 1 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[54952,1884,5.34,4.65,-0.19960902569216,0.45165573581742,"*",0.303526,"TRNAU1AP","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0003723//RNA binding","GO:0001514//selenocysteine incorporation","K13201//nucleolysin TIA-1/TIAR;K13126//polyadenylate-binding protein;K15174//RNA polymerase II-associated factor 1","XP_017390246.1//PREDICTED: tRNA selenocysteine 1-associated protein 1 isoform X1 [Cebus capucinus imitator]",4]
[93621,2127,67.13,58.46,-0.199507813269682,0.000166925182513661,"*",{"v":4.01586e-05,"d":"4.02E-05"},"MRFAP1","GO:0005634//nucleus;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm","NA","NA","K07190//phosphorylase kinase alpha/beta subunit;K01064//wingless-type MMTV integration site family, member 9","XP_011770269.1//PREDICTED: MORF4 family-associated protein 1-like [Macaca nemestrina]","1//3;2//1"]
[1143,2267,0.7,0.61,-0.19854567938208,0.563911062851215,"*",0.408336,"CHRNB4","GO:0005892//acetylcholine-gated channel complex;GO:0030054//cell junction;GO:0043005//neuron projection;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane;GO:0070821//tertiary granule membrane;GO:0005886//plasma membrane;GO:0045211//postsynaptic membrane","GO:0015276//ligand-gated ion channel activity;GO:0042166//acetylcholine binding;GO:0008144//drug binding;GO:0046982//protein heterodimerization activity;GO:0022848//acetylcholine-gated cation-selective channel activity;GO:0015464//acetylcholine receptor activity","GO:0051291//protein heterooligomerization;GO:0035094//response to nicotine;GO:0051971//positive regulation of transmission of nerve impulse;GO:0035095//behavioral response to nicotine;GO:0007165//signal transduction;GO:0006939//smooth muscle contraction;GO:0006811//ion transport;GO:0006940//regulation of smooth muscle contraction;GO:0007271//synaptic transmission, cholinergic;GO:0007626//locomotory behavior;GO:0001508//action potential;GO:0043312//neutrophil degranulation;GO:0046928//regulation of neurotransmitter secretion;GO:0060084//synaptic transmission involved in micturition","K04815//nicotinic acetylcholine receptor beta-4","NP_000741.1//neuronal acetylcholine receptor subunit beta-4 isoform 1 precursor [Homo sapiens];NP_001243496.1//neuronal acetylcholine receptor subunit beta-4 isoform 2 precursor [Homo sapiens]","4;2//1"]
[80221,2135,7.16,6.24,-0.198413558402008,0.292708632245599,"*",0.170707,"ACSF2","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0005524//ATP binding;GO:0003824//catalytic activity;GO:0016874//ligase activity;GO:0003996//acyl-CoA ligase activity","GO:0008152//metabolic process;GO:0006631//fatty acid metabolic process;GO:0006637//acyl-CoA metabolic process","K00666//fatty-acyl-CoA synthase [EC:6.2.1.-]","NP_001275899.1//acyl-CoA synthetase family member 2, mitochondrial isoform 4 [Homo sapiens];AAH14123.1//Acyl-CoA synthetase family member 2 [Homo sapiens];NP_001275898.1//acyl-CoA synthetase family member 2, mitochondrial isoform 3 [Homo sapiens];NP_079425.3//acyl-CoA synthetase family member 2, mitochondrial isoform 2 precursor [Homo sapiens];NP_001275897.1//acyl-CoA synthetase family member 2, mitochondrial isoform 1 [Homo sapiens]","1//3;5"]
[5475,2687,0.39,0.34,-0.197939377611909,0.906705003209414,"*",0.848922,"PPEF1","GO:0005829//cytosol","GO:0004721//phosphoprotein phosphatase activity;GO:0005506//iron ion binding;GO:0005509//calcium ion binding;GO:0004722//protein serine/threonine phosphatase activity;GO:0030145//manganese ion binding","GO:0006470//protein dephosphorylation;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0050906//detection of stimulus involved in sensory perception","K13807//serine/threonine-protein phosphatase with EF-hands [EC:3.1.3.16]","NP_689410.1//serine/threonine-protein phosphatase with EF-hands 1 isoform 1b [Homo sapiens];NP_006231.2//serine/threonine-protein phosphatase with EF-hands 1 isoform 1 [Homo sapiens];NP_689412.1//serine/threonine-protein phosphatase with EF-hands 1 isoform 3 [Homo sapiens]","1//3;2//1"]
[3224,2290,4.93,4.3,-0.197250986788451,0.420028598187887,"*",0.275698,"HOXC8","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0015630//microtubule cytoskeleton","GO:0003677//DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0009952//anterior/posterior pattern specification;GO:0030182//neuron differentiation;GO:0007275//multicellular organism development;GO:0006351//transcription, DNA-templated;GO:0048705//skeletal system morphogenesis","K09308//homeobox protein HoxB/C/D8","XP_022267180.1//uncharacterized protein LOC607625 [Canis lupus familiaris]","3//A2MP1"]
[10892,5046,5.58,4.87,-0.196343349746845,0.154716857682403,"*",0.0789856,"MALT1","GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0005730//nucleolus;GO:0043234//protein complex;GO:0005829//cytosol;GO:0032449//CBM complex;GO:0001650//fibrillar center;GO:0005886//plasma membrane","GO:0002020//protease binding;GO:0019209//kinase activator activity;GO:0008233//peptidase activity;GO:0042802//identical protein binding;GO:0004197//cysteine-type endopeptidase activity;GO:0004871//signal transducer activity;GO:0043621//protein self-association;GO:0004842//ubiquitin-protein transferase activity","GO:0009620//response to fungus;GO:0002237//response to molecule of bacterial origin;GO:0032743//positive regulation of interleukin-2 production;GO:0051168//nuclear export;GO:0045087//innate immune response;GO:0051259//protein oligomerization;GO:0050852//T cell receptor signaling pathway;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0007250//activation of NF-kappaB-inducing kinase activity;GO:0031398//positive regulation of protein ubiquitination;GO:0043066//negative regulation of apoptotic process;GO:0050870//positive regulation of T cell activation;GO:0050856//regulation of T cell receptor signaling pathway;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0042098//T cell proliferation;GO:0006508//proteolysis;GO:0006952//defense response;GO:0002726//positive regulation of T cell cytokine production;GO:0001923//B-1 B cell differentiation;GO:0042981//regulation of apoptotic process","K07369//mucosa-associated lymphoid tissue lymphoma translocation protein 1 [EC:3.4.22.-]","NP_006776.1//mucosa-associated lymphoid tissue lymphoma translocation protein 1 isoform a [Homo sapiens];NP_776216.1//mucosa-associated lymphoid tissue lymphoma translocation protein 1 isoform b [Homo sapiens]","3//A2MP1;2//1"]
[1947,3344,4.49,3.92,-0.195861790625939,0.344964531791908,"*",0.209216,"EFNB1","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0045121//membrane raft;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0045202//synapse;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0046875//ephrin receptor binding","GO:0001755//neural crest cell migration;GO:0042102//positive regulation of T cell proliferation;GO:0048013//ephrin receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0031295//T cell costimulation;GO:0007155//cell adhesion;GO:0009880//embryonic pattern specification;GO:0007411//axon guidance","K05463//ephrin-B","XP_009233224.1//PREDICTED: LOW QUALITY PROTEIN: ephrin-B1 [Pongo abelii]",4]
[9351,2050,25.12,21.95,-0.194615524468907,0.23411273822013,"*",0.1307596,"SLC9A3R2","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0012505//endomembrane system;GO:0005634//nucleus;GO:0005925//focal adhesion;GO:0016324//apical plasma membrane;GO:0005886//plasma membrane","GO:0032947//protein complex scaffold activity;GO:0008022//protein C-terminus binding;GO:0019902//phosphatase binding;GO:0005102//receptor binding;GO:0045296//cadherin binding;GO:0008013//beta-catenin binding","GO:0006461//protein complex assembly","K13358//Na(+)/H(+) exchange regulatory cofactor NHE-RF2","AAH14513.2//SLC9A3R2 protein, partial [Homo sapiens];XP_016879383.1//PREDICTED: Na(+)/H(+) exchange regulatory cofactor NHE-RF2 isoform X1 [Homo sapiens];XP_005590983.1//PREDICTED: Na(+)/H(+) exchange regulatory cofactor NHE-RF2 [Macaca fascicularis]","1//3;2//1;5"]
[9987,4155,47.98,41.94,-0.194106296196842,{"v":2.55583041464146e-05,"d":"2.56E-05"},"*",{"v":5.33278e-06,"d":"5.33E-06"},"HNRNPDL","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0030529//intracellular ribonucleoprotein complex;GO:0005829//cytosol;GO:0019013//viral nucleocapsid","GO:0008143//poly(A) binding;GO:0003697//single-stranded DNA binding;GO:0003723//RNA binding;GO:0003677//DNA binding;GO:0034046//poly(G) binding;GO:0003690//double-stranded DNA binding","GO:0006396//RNA processing;GO:0010468//regulation of gene expression;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0035722//interleukin-12-mediated signaling pathway","K13044//heterogeneous nuclear ribonucleoprotein A/B/D","NP_001193929.1//heterogeneous nuclear ribonucleoprotein D-like isoform b [Homo sapiens];NP_112740.1//heterogeneous nuclear ribonucleoprotein D-like isoform a [Homo sapiens]","1//3;3//A2MP1"]
[387263,4116,6.29,5.5,-0.193628398467267,0.166410205992964,"*",0.085872,"C6orf120","GO:0070062//extracellular exosome;GO:0035578//azurophil granule lumen;GO:0005576//extracellular region","NA","GO:0043312//neutrophil degranulation;GO:0006915//apoptotic process","K22197//BRG1-associated factor 45A","NP_001304271.1//UPF0669 protein C6orf120 isoform 2 precursor [Homo sapiens];XP_008971840.1//PREDICTED: LOW QUALITY PROTEIN: UPF0669 protein C6orf120 homolog [Pan paniscus]","1//3;2//1"]
[92667,2330,17.95,15.7,-0.193219284931424,0.0453098740853933,"*",0.01893348,"MGME1","GO:0005739//mitochondrion","GO:0008297//single-stranded DNA exodeoxyribonuclease activity;GO:0003677//DNA binding","GO:0006264//mitochondrial DNA replication;GO:0000002//mitochondrial genome maintenance;GO:0043504//mitochondrial DNA repair","K19465//mitochondrial genome maintenance exonuclease 1 [EC:3.1.-.-]","NP_001297267.1//mitochondrial genome maintenance exonuclease 1 isoform 1 precursor [Homo sapiens];NP_001297268.1//mitochondrial genome maintenance exonuclease 1 isoform 3 precursor [Homo sapiens];NP_443097.1//mitochondrial genome maintenance exonuclease 1 isoform 2 precursor [Homo sapiens]","1//3;3//A2MP1"]
[51702,3189,4.64,4.06,-0.192645077942396,0.364779258270106,"*",0.225732,"PADI3","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0042802//identical protein binding;GO:0005509//calcium ion binding;GO:0004668//protein-arginine deiminase activity","GO:0018101//protein citrullination;GO:0006325//chromatin organization;GO:0036414//histone citrullination","K01481//protein-arginine deiminase [EC:3.5.3.15]","NP_057317.2//protein-arginine deiminase type-3 [Homo sapiens]","2//1"]
[145389,1727,19.69,17.23,-0.192540409676605,0.154391552,"*",0.0787712,"SLC38A6","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0015171//amino acid transmembrane transporter activity","GO:0003333//amino acid transmembrane transport;GO:0006814//sodium ion transport","K14993//solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 6","NP_001166173.1//probable sodium-coupled neutral amino acid transporter 6 isoform 1 [Homo sapiens];NP_722518.2//probable sodium-coupled neutral amino acid transporter 6 isoform 2 [Homo sapiens]","1//3;2//1"]
[353116,2795,7.95,6.96,-0.191867554322989,0.106586181635087,"*",0.0503572,"RILPL1","GO:0005929//cilium;GO:0036064//ciliary basal body;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005813//centrosome;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0031267//small GTPase binding;GO:0051959//dynein light intermediate chain binding;GO:0046983//protein dimerization activity","GO:1903445//protein transport from ciliary membrane to plasma membrane;GO:0060271//cilium assembly;GO:0003382//epithelial cell morphogenesis;GO:1901214//regulation of neuron death","K20173//RILP-like protein 1","NP_847884.2//RILP-like protein 1 isoform 1 [Homo sapiens];NP_001306172.1//RILP-like protein 1 isoform 2 [Homo sapiens];NP_001306173.1//RILP-like protein 1 isoform 3 [Homo sapiens]","4;1//3"]
[339448,1705,22.77,19.94,-0.191468881738426,0.104253941192123,"*",0.049053,"C1orf174","GO:0005634//nucleus","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K12022//tripartite motif-containing protein 46;K11447//histone demethylase [EC:1.14.11.-];K01064//wingless-type MMTV integration site family, member 9","AAH35643.1//C1orf174 protein, partial [Homo sapiens]","2//1"]
[29902,1529,13.23,11.59,-0.190932495272205,0.275418542339016,"*",0.1587786,"FAM216A","NA","NA","NA","K06883//uncharacterized protein","XP_509366.3//PREDICTED: protein FAM216A, partial [Pan troglodytes]","2//1"]
[4901,3535,0.97,0.85,-0.190521906049426,0.762462227531122,"*",0.663324,"NRL","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:1990841//promoter-specific chromatin binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0043522//leucine zipper domain binding","GO:0007399//nervous system development;GO:0046548//retinal rod cell development;GO:0007601//visual perception;GO:0006366//transcription from RNA polymerase II promoter;GO:0045872//positive regulation of rhodopsin gene expression;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0050896//response to stimulus;GO:0007468//regulation of rhodopsin gene expression","K09038//neural retina-specific leucine zipper protein","XP_011535103.2//PREDICTED: neural retina-specific leucine zipper protein isoform X1 [Homo sapiens];XP_012322914.1//neural retina-specific leucine zipper protein isoform X1 [Aotus nancymaae];XP_017400145.1//PREDICTED: neural retina-specific leucine zipper protein [Cebus capucinus imitator];XP_011535108.2//PREDICTED: neural retina-specific leucine zipper protein isoform X3 [Homo sapiens]","4;1//3"]
[200205,7661,2.84,2.49,-0.189745187436601,0.236786098378257,"*",0.1325344,"IBA57","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0003723//RNA binding;GO:0016740//transferase activity","GO:0016226//iron-sulfur cluster assembly;GO:0006783//heme biosynthetic process","K22073//transferase CAF17, mitochondrial [EC:2.1.-.-]","NP_001010867.1//putative transferase CAF17, mitochondrial isoform 1 precursor [Homo sapiens];XP_011941595.1//PREDICTED: putative transferase CAF17, mitochondrial isoform X11 [Cercocebus atys]","1//3;3//A2MP1"]
[3178,1817,402.32,352.79,-0.189533790930036,{"v":3.75816120666014e-16,"d":"3.76E-16"},"*",{"v":2.40208e-17,"d":"2.40E-17"},"HNRNPA1","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0071013//catalytic step 2 spliceosome;GO:0005681//spliceosomal complex;GO:0005829//cytosol;GO:0030529//intracellular ribonucleoprotein complex;GO:1990826//nucleoplasmic periphery of the nuclear pore complex;GO:0019013//viral nucleocapsid","GO:0061752//telomeric repeat-containing RNA binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0098505//G-rich strand telomeric DNA binding;GO:0036310//annealing helicase activity;GO:0003697//single-stranded DNA binding;GO:1990825//sequence-specific mRNA binding;GO:0036002//pre-mRNA binding;GO:0019904//protein domain specific binding;GO:0035198//miRNA binding;GO:0033592//RNA strand annealing activity;GO:0008134//transcription factor binding;GO:0003727//single-stranded RNA binding","GO:0030324//lung development;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0042149//cellular response to glucose starvation;GO:0051028//mRNA transport;GO:0008584//male gonad development;GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0051168//nuclear export;GO:0032211//negative regulation of telomere maintenance via telomerase;GO:0035865//cellular response to potassium ion;GO:0016070//RNA metabolic process;GO:1903936//cellular response to sodium arsenite;GO:1904579//cellular response to thapsigargin;GO:0051170//nuclear import;GO:1904577//cellular response to tunicamycin;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0045760//positive regulation of action potential;GO:0010628//positive regulation of gene expression;GO:0019087//transformation of host cell by virus;GO:0008380//RNA splicing","K12741//heterogeneous nuclear ribonucleoprotein A1/A3","BAE40987.1//unnamed protein product [Mus musculus];ERE84424.1//heterogeneous nuclear ribonucleoprotein A1 [Cricetulus griseus]","3//A2MP1"]
[388121,2020,2.44,2.14,-0.189270351161739,0.61784137730164,"*",0.462124,"TNFAIP8L3","GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0008526//phosphatidylinositol transporter activity;GO:0035091//phosphatidylinositol binding","GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0048017//inositol lipid-mediated signaling;GO:0051897//positive regulation of protein kinase B signaling;GO:0015914//phospholipid transport;GO:0006644//phospholipid metabolic process;GO:0019216//regulation of lipid metabolic process;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0042981//regulation of apoptotic process","K12471//epsin;K15696//RING finger protein 113B;K17985//activating molecule in BECN1-regulated autophagy protein 1;K01064//wingless-type MMTV integration site family, member 9","NP_997264.2//tumor necrosis factor alpha-induced protein 8-like protein 3 isoform 1 [Homo sapiens];XP_003266971.2//PREDICTED: LOW QUALITY PROTEIN: tumor necrosis factor alpha-induced protein 8-like protein 3 [Nomascus leucogenys]","1//3;3//A2MP1"]
[25880,1465,4.98,4.37,-0.188512462567483,0.561794995236033,"*",0.40603,"TMEM186","GO:0016021//integral component of membrane;GO:0005739//mitochondrion","NA","NA","NA","NP_056236.2//transmembrane protein 186 [Homo sapiens]","3//A2MP1"]
[9330,4338,9.82,8.62,-0.188035155225595,0.0996036714745308,"*",0.0465158,"GTF3C3","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0005730//nucleolus;GO:0000127//transcription factor TFIIIC complex","GO:0003677//DNA binding","GO:0006359//regulation of transcription from RNA polymerase III promoter;GO:0042791//5S class rRNA transcription from RNA polymerase III type 1 promoter;GO:0042797//tRNA transcription from RNA polymerase III promoter;GO:0006351//transcription, DNA-templated;GO:0006383//transcription from RNA polymerase III promoter","K15201//general transcription factor 3C polypeptide 3 (transcription factor C subunit 4)","NP_001193703.1//general transcription factor 3C polypeptide 3 isoform 2 [Homo sapiens];NP_036218.1//general transcription factor 3C polypeptide 3 isoform 1 [Homo sapiens]","4;1//3"]
[51299,1574,0.41,0.36,-0.187627003175771,0.882334490780142,"*",0.817764,"NRN1","GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0030054//cell junction;GO:0046658//anchored component of plasma membrane;GO:0032281//AMPA glutamate receptor complex;GO:0045202//synapse;GO:0005886//plasma membrane;GO:0031225//anchored component of membrane","GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity","GO:0007399//nervous system development;GO:0006501//C-terminal protein lipidation;GO:1990138//neuron projection extension","K05726//breast cancer anti-estrogen resistance 1","NP_057672.1//neuritin isoform 1 precursor [Homo sapiens];NP_001265640.1//neuritin isoform 2 [Homo sapiens]","1//3;2//1"]
[7681,2744,0.99,0.87,-0.186413124230881,0.734254791066706,"*",0.625684,"MKRN3","GO:0030529//intracellular ribonucleoprotein complex","GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0016740//transferase activity","GO:0016567//protein ubiquitination","K15687//E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]","NP_005655.1//probable E3 ubiquitin-protein ligase makorin-3 [Homo sapiens]","3//A2MP1"]
[51606,2179,15.7,13.8,-0.186096292113458,0.150064872255834,"*",0.0760846,"ATP6V1H","GO:0005765//lysosomal membrane;GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0000221//vacuolar proton-transporting V-type ATPase, V1 domain;GO:0005886//plasma membrane","GO:0030234//enzyme regulator activity;GO:0046961//proton-transporting ATPase activity, rotational mechanism","GO:0016241//regulation of macroautophagy;GO:0008286//insulin receptor signaling pathway;GO:0034220//ion transmembrane transport;GO:0050690//regulation of defense response to virus by virus;GO:0090383//phagosome acidification;GO:0007035//vacuolar acidification;GO:0015991//ATP hydrolysis coupled proton transport;GO:0006897//endocytosis;GO:0033572//transferrin transport","K02144//V-type H+-transporting ATPase subunit H","NP_998784.1//V-type proton ATPase subunit H isoform 2 [Homo sapiens];NP_998785.1//V-type proton ATPase subunit H isoform 1 [Homo sapiens]","3//A2MP1;2//1"]
[253769,3063,2.66,2.34,-0.184917715917785,0.284373119913514,"*",0.1646708,"WDR27","GO:0005654//nucleoplasm","NA","NA","K22069//LYR motif-containing protein 4;K14963//COMPASS component SWD3","NP_001337552.1//WD repeat-containing protein 27 isoform 3 [Homo sapiens];NP_872358.4//WD repeat-containing protein 27 isoform 1 [Homo sapiens];NP_001189479.1//WD repeat-containing protein 27 isoform 2 [Homo sapiens];NP_001337553.1//WD repeat-containing protein 27 isoform 4 [Homo sapiens]","4;1//3"]
[11157,789,9.74,8.57,-0.184626567969842,0.567748674840269,"*",0.411648,"LSM6","NA","NA","NA","K12625//U6 snRNA-associated Sm-like protein LSm6","XP_008587467.1//PREDICTED: U6 snRNA-associated Sm-like protein LSm6 isoform X1 [Galeopterus variegatus]","2//1"]
[114884,4231,2.92,2.57,-0.184200009686139,0.419244710754843,"*",0.275026,"OSBPL10","GO:0005856//cytoskeleton;GO:0005829//cytosol","GO:0015485//cholesterol binding;GO:0001786//phosphatidylserine binding;GO:0005548//phospholipid transporter activity","GO:0036150//phosphatidylserine acyl-chain remodeling;GO:0006869//lipid transport","K20465//oxysterol-binding protein-related protein 9/10/11","NP_001167531.1//oxysterol-binding protein-related protein 10 isoform 2 [Homo sapiens];NP_060254.2//oxysterol-binding protein-related protein 10 isoform 1 [Homo sapiens]","1//3;4"]
[57591,4374,27.73,24.42,-0.183384416052075,1.39846247560976E-3,"*",0.000402012,"MKL1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0003779//actin binding;GO:0003713//transcription coactivator activity;GO:0001105//RNA polymerase II transcription coactivator activity;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0003785//actin monomer binding;GO:0003700//DNA binding transcription factor activity;GO:0043522//leucine zipper domain binding","GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0030036//actin cytoskeleton organization;GO:0051145//smooth muscle cell differentiation;GO:0010735//positive regulation of transcription via serum response element binding;GO:0030900//forebrain development;GO:0001764//neuron migration;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0031175//neuron projection development;GO:2001234//negative regulation of apoptotic signaling pathway","K03006//DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6];K17582//antigen KI-67;K13172//serine/arginine repetitive matrix protein 2","XP_016794708.1//PREDICTED: MKL/myocardin-like protein 1 isoform X2 [Pan troglodytes];NP_001305068.1//MKL/myocardin-like protein 1 isoform 4 [Homo sapiens];XP_016794707.1//PREDICTED: MKL/myocardin-like protein 1 isoform X1 [Pan troglodytes]","4;1//3"]
[79892,4277,29.13,25.66,-0.182984531050666,0.00240611731230546,"*",0.000725872,"MCMBP","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0042555//MCM complex;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0000790//nuclear chromatin","GO:0003682//chromatin binding","GO:0007062//sister chromatid cohesion;GO:0051301//cell division;GO:0006261//DNA-dependent DNA replication","K05700//vinculin","NP_079110.1//mini-chromosome maintenance complex-binding protein isoform 1 [Homo sapiens];XP_016872153.1//PREDICTED: mini-chromosome maintenance complex-binding protein isoform X4 [Homo sapiens];NP_001243307.1//mini-chromosome maintenance complex-binding protein isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[64801,1559,21.81,19.22,-0.182381433867,0.190190626228733,"*",0.1007746,"ARV1","GO:0005794//Golgi apparatus;GO:0032541//cortical endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0015248//sterol transporter activity","GO:0006665//sphingolipid metabolic process;GO:0032383//regulation of intracellular cholesterol transport;GO:0090181//regulation of cholesterol metabolic process;GO:0097036//regulation of plasma membrane sterol distribution;GO:0006695//cholesterol biosynthetic process;GO:0030301//cholesterol transport;GO:0008206//bile acid metabolic process","K21848//lipid intermediate transporter","NP_073623.1//protein ARV1 isoform 2 [Homo sapiens];NP_001333921.1//protein ARV1 isoform 1 [Homo sapiens]","1//3;2//1"]
[10477,1593,37.27,32.85,-0.182121448519158,0.0535195665544003,"*",0.02288,"UBE2E3","NA","NA","NA","K20217//ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]","XP_008136725.1//PREDICTED: ubiquitin-conjugating enzyme E2 E3 [Eptesicus fuscus];XP_021498997.1//ubiquitin-conjugating enzyme E2 E3 isoform X1 [Meriones unguiculatus]","1//3;3//A2MP1;2//1"]
[283337,4256,7.26,6.4,-0.181897643108388,0.180768522345635,"*",0.0947524,"ZNF740","NA","GO:0003676//nucleic acid binding","NA","K09228//KRAB domain-containing zinc finger protein","XP_013988087.1//PREDICTED: gastrula zinc finger protein XlCGF58.1-like isoform X2 [Salmo salar]","3//A2MP1"]
[83606,3518,27.27,24.06,-0.180678057739187,0.0102769524242424,"*",3.56676E-3,"GUCD1","NA","NA","NA","K01368//cathepsin S [EC:3.4.22.27];K11088//small nuclear ribonucleoprotein D3;K11447//histone demethylase [EC:1.14.11.-];K21125//mucin-5AC;K01064//wingless-type MMTV integration site family, member 9","AAH53529.1//C22orf13 protein, partial [Homo sapiens];NP_001271181.1//protein GUCD1 isoform b [Homo sapiens];NP_001271180.1//protein GUCD1 isoform a [Homo sapiens];NP_001271182.1//protein GUCD1 isoform c [Homo sapiens];BAG58044.1//unnamed protein product [Homo sapiens]","1//3;3//A2MP1"]
[8139,4544,0.85,0.75,-0.180572245641821,0.66026762938026,"*",0.540234,"GAN","GO:0005737//cytoplasm;GO:0031463//Cul3-RING ubiquitin ligase complex","NA","GO:0016567//protein ubiquitination;GO:0007010//cytoskeleton organization","K10453//kelch-like protein 16 (gigaxonin)","XP_016785723.1//PREDICTED: gigaxonin [Pan troglodytes]","3//A2MP1"]
[58516,3075,19.13,16.88,-0.180521969638927,0.0363267436989048,"*",0.0147431,"SINHCAF","NA","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K07560//D-tyrosyl-tRNA(Tyr) deacylase [EC:3.1.-.-];K11447//histone demethylase [EC:1.14.11.-];K09488//TNF receptor-associated protein 1;K20164//DENN domain-containing protein 5","XP_021777849.1//protein FAM60A isoform X1 [Papio anubis];XP_019592493.1//PREDICTED: protein FAM60A isoform X1 [Rhinolophus sinicus];XP_006986736.2//PREDICTED: protein FAM60A isoform X1 [Peromyscus maniculatus bairdii]","1//3;2//1"]
[84645,1777,1.54,1.36,-0.179323699444562,0.734308736757035,"*",0.625684,"C22orf23","NA","NA","NA","NA","XP_003264785.1//PREDICTED: UPF0193 protein EVG1 isoform X3 [Nomascus leucogenys];XP_012363215.1//PREDICTED: UPF0193 protein EVG1 isoform X1 [Nomascus leucogenys]","1//3;4"]
[10928,4368,17.5,15.46,-0.178814602794844,0.0251776129789303,"*",0.00972492,"RALBP1","GO:0016020//membrane;GO:0005829//cytosol;GO:0005622//intracellular","GO:0048365//Rac GTPase binding;GO:0017160//Ral GTPase binding;GO:0043492//ATPase activity, coupled to movement of substances;GO:0022857//transmembrane transporter activity;GO:0005096//GTPase activator activity;GO:0016887//ATPase activity","GO:0006810//transport;GO:0055085//transmembrane transport;GO:0007165//signal transduction;GO:0043547//positive regulation of GTPase activity;GO:0043087//regulation of GTPase activity;GO:0007264//small GTPase mediated signal transduction;GO:0006897//endocytosis;GO:0006935//chemotaxis;GO:0051056//regulation of small GTPase mediated signal transduction","K08773//RalA-binding protein 1","NP_006779.1//ralA-binding protein 1 [Homo sapiens]","3//A2MP1"]
[5337,6025,1.46,1.29,-0.178597303456763,0.610737518228509,"*",0.454096,"PLD1","GO:0016020//membrane;GO:0005765//lysosomal membrane;GO:0016324//apical plasma membrane;GO:0005622//intracellular;GO:0031902//late endosome membrane;GO:0048471//perinuclear region of cytoplasm;GO:0000139//Golgi membrane;GO:0005768//endosome;GO:0030139//endocytic vesicle;GO:0005794//Golgi apparatus;GO:0035579//specific granule membrane;GO:0005789//endoplasmic reticulum membrane;GO:0070821//tertiary granule membrane;GO:0005886//plasma membrane","GO:0004630//phospholipase D activity;GO:0070290//N-acylphosphatidylethanolamine-specific phospholipase D activity;GO:0035091//phosphatidylinositol binding","GO:0048017//inositol lipid-mediated signaling;GO:0016042//lipid catabolic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0032534//regulation of microvillus assembly;GO:0048870//cell motility;GO:0007264//small GTPase mediated signal transduction;GO:0043312//neutrophil degranulation;GO:0006935//chemotaxis;GO:0007265//Ras protein signal transduction","K01115//phospholipase D1/2 [EC:3.1.4.4]","NP_002653.1//phospholipase D1 isoform a [Homo sapiens];BAD93144.1//phospholipase D1 variant, partial [Homo sapiens]","4;2//1"]
[4215,4806,10.16,8.98,-0.178113052031019,0.0826698627071823,"*",0.037469,"MAP3K3","GO:0005829//cytosol;GO:0005622//intracellular;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0004709//MAP kinase kinase kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity","GO:0000165//MAPK cascade;GO:0007346//regulation of mitotic cell cycle;GO:0032147//activation of protein kinase activity;GO:0035556//intracellular signal transduction;GO:0001568//blood vessel development;GO:0046777//protein autophosphorylation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:1900745//positive regulation of p38MAPK cascade;GO:0042981//regulation of apoptotic process;GO:0031098//stress-activated protein kinase signaling cascade","K04421//mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]","NP_002392.2//mitogen-activated protein kinase kinase kinase 3 isoform 2 [Homo sapiens];NP_976226.1//mitogen-activated protein kinase kinase kinase 3 isoform 1 [Homo sapiens];NP_001317360.1//mitogen-activated protein kinase kinase kinase 3 isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[126295,1917,1.64,1.45,-0.177642914603149,0.650788005938144,"*",0.493978,"ZNF57","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_012291640.1//zinc finger protein 57 [Aotus nancymaae]","1//3;2//1"]
[10124,2990,8.91,7.88,-0.177229802065546,0.228837480949702,"*",0.1273118,"ARL4A","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0005525//GTP binding","GO:0007264//small GTPase mediated signal transduction;GO:0050873//brown fat cell differentiation","K07945//ADP-ribosylation factor-like protein 4","XP_003255929.2//PREDICTED: ADP-ribosylation factor-like protein 4A [Nomascus leucogenys]","4;1//3;3//A2MP1;2//1"]
[158038,13799,0.26,0.23,-0.176877762084079,0.647255753580779,"*",0.526184,"LINGO2","NA","NA","NA","K07523//netrin-G1 ligand;K16351//netrin-G2 ligand","XP_001505252.1//PREDICTED: leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 [Ornithorhynchus anatinus]","1//3;3//A2MP1;2//1"]
[57684,2008,1.4,1.24,-0.175086706558091,0.73418737800437,"*",0.63105,"ZBTB26","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0042802//identical protein binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein;K10505//zinc finger and BTB domain-containing protein 26","XP_014384383.1//PREDICTED: zinc finger and BTB domain-containing protein 26 isoform X1 [Myotis brandtii];XP_009186400.1//zinc finger and BTB domain-containing protein 26 isoform X1 [Papio anubis]","1//3;3//A2MP1"]
[653121,7273,5,4.43,-0.174621396107069,0.192218332280123,"*",0.1020656,"ZBTB8A","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K10495//zinc finger and BTB domain-containing protein 8","NP_001035531.2//zinc finger and BTB domain-containing protein 8A isoform 1 [Homo sapiens];NP_001278425.1//zinc finger and BTB domain-containing protein 8A isoform 2 [Homo sapiens]","1//3;2//1"]
[29964,1646,2.99,2.65,-0.174153124747544,0.643597175980883,"*",0.522686,"PRICKLE4","NA","NA","NA","K04511//prickle","XP_011928777.1//PREDICTED: prickle-like protein 4 isoform X2 [Cercocebus atys]",5]
[267,3475,28.59,25.35,-0.173524872740395,1.12530865854199E-3,"*",0.000317924,"AMFR","GO:0016020//membrane;GO:0030425//dendrite;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0044322//endoplasmic reticulum quality control compartment;GO:0048471//perinuclear region of cytoplasm;GO:0043025//neuronal cell body;GO:0030426//growth cone;GO:0043234//protein complex;GO:0005794//Golgi apparatus;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0036513//Derlin-1 retrotranslocation complex;GO:0005789//endoplasmic reticulum membrane","GO:0061630//ubiquitin protein ligase activity;GO:0004872//receptor activity;GO:0030674//protein binding, bridging;GO:0042802//identical protein binding;GO:0051087//chaperone binding;GO:1990381//ubiquitin-specific protease binding;GO:1904264//ubiquitin protein ligase activity involved in ERAD pathway;GO:0004842//ubiquitin-protein transferase activity;GO:0034450//ubiquitin-ubiquitin ligase activity;GO:1904288//BAT3 complex binding;GO:0046872//metal ion binding","GO:0070936//protein K48-linked ubiquitination;GO:1904380//endoplasmic reticulum mannose trimming;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0032092//positive regulation of protein binding;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0036503//ERAD pathway;GO:0051865//protein autoubiquitination;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0007611//learning or memory;GO:0000209//protein polyubiquitination;GO:0051259//protein oligomerization;GO:0006457//protein folding;GO:0007165//signal transduction;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0007568//aging;GO:0006928//movement of cell or subcellular component","K10636//autocrine motility factor receptor [EC:2.3.2.27]","NP_001135.3//E3 ubiquitin-protein ligase AMFR isoform c [Homo sapiens];XP_007991537.1//PREDICTED: E3 ubiquitin-protein ligase AMFR [Chlorocebus sabaeus]","1//3;5"]
[23247,6640,5.03,4.46,-0.173514689885222,0.180723168558117,"*",0.094706,"KIAA0556","GO:0005856//cytoskeleton;GO:0005615//extracellular space;GO:0042995//cell projection;GO:0005737//cytoplasm","NA","NA","K21125//mucin-5AC","EAW55743.1//KIAA0556 protein [Homo sapiens]","3//A2MP1"]
[51088,7350,11.5,10.2,-0.17306470897288,0.0117253818136558,"*",0.00412818,"KLHL5","GO:0005856//cytoskeleton;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0031463//Cul3-RING ubiquitin ligase complex","GO:0003779//actin binding","GO:0043687//post-translational protein modification;GO:0016567//protein ubiquitination","K10442//kelch-like protein 1/4/5","NP_057074.3//kelch-like protein 5 isoform 1 [Homo sapiens];XP_005262712.1//PREDICTED: kelch-like protein 5 isoform X2 [Homo sapiens];BAD92057.1//kelch-like 5 isoform 2 variant, partial [Homo sapiens];NP_950240.2//kelch-like protein 5 isoform 2 [Homo sapiens]","4;1//3;3//A2MP1;2//1"]
[84552,3847,3.29,2.92,-0.172119214855224,0.456342737918216,"*",0.30739,"PARD6G","GO:0043234//protein complex;GO:0005829//cytosol;GO:0005923//bicellular tight junction;GO:0005886//plasma membrane","NA","GO:0070830//bicellular tight junction assembly;GO:0007163//establishment or maintenance of cell polarity;GO:0051301//cell division;GO:0007049//cell cycle","K06093//partitioning defective protein 6","NP_115899.1//partitioning defective 6 homolog gamma [Homo sapiens]","3//A2MP1"]
[10732,2657,5.78,5.13,-0.172110666893625,0.429009075011854,"*",0.283204,"TCFL5","GO:0005634//nucleus;GO:0001673//male germ cell nucleus","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0001078//transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0046983//protein dimerization activity","GO:0030154//cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0042127//regulation of cell proliferation;GO:0007283//spermatogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007275//multicellular organism development;GO:0045595//regulation of cell differentiation","K09092//transcription factor-like 5","NP_001288655.1//transcription factor-like 5 protein isoform 2 [Homo sapiens];NP_006593.2//transcription factor-like 5 protein isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[54784,2138,7.69,6.83,-0.171098019671736,0.393422718538167,"*",0.250698,"ALKBH4","GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0030496//midbody;GO:0070938//contractile ring","GO:0003779//actin binding;GO:0046872//metal ion binding;GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;GO:0032451//demethylase activity","GO:0036090//cleavage furrow ingression;GO:0031032//actomyosin structure organization;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0070988//demethylation;GO:0006482//protein demethylation","K10766//alkylated DNA repair protein alkB homolog 4 [EC:1.14.11.-]","XP_017713105.1//PREDICTED: alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 [Rhinopithecus bieti]","3//A2MP1"]
[8635,1250,8.8,7.82,-0.170334916217307,0.511819707045291,"*",0.35655,"RNASET2","GO:0070062//extracellular exosome;GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0035578//azurophil granule lumen;GO:0043202//lysosomal lumen;GO:0005576//extracellular region;GO:0005764//lysosome","GO:0003723//RNA binding;GO:0033897//ribonuclease T2 activity;GO:0004540//ribonuclease activity","GO:0006401//RNA catabolic process;GO:0043312//neutrophil degranulation","K01166//ribonuclease T2 [EC:3.1.27.1]","NP_003721.2//ribonuclease T2 precursor [Homo sapiens]",4]
[5264,1620,17.8,15.82,-0.170127641380968,0.233585366502242,"*",0.1304358,"PHYH","GO:0005782//peroxisomal matrix;GO:0005777//peroxisome;GO:0005739//mitochondrion","GO:0031406//carboxylic acid binding;GO:0048244//phytanoyl-CoA dioxygenase activity;GO:0048037//cofactor binding;GO:0031418//L-ascorbic acid binding;GO:0008198//ferrous iron binding","GO:0001561//fatty acid alpha-oxidation;GO:0006720//isoprenoid metabolic process;GO:0006103//2-oxoglutarate metabolic process;GO:0097089//methyl-branched fatty acid metabolic process","K00477//phytanoyl-CoA hydroxylase [EC:1.14.11.18]","NP_006205.1//phytanoyl-CoA dioxygenase, peroxisomal isoform a precursor [Homo sapiens];EAW86295.1//phytanoyl-CoA 2-hydroxylase, isoform CRA_b [Homo sapiens];EAW86294.1//phytanoyl-CoA 2-hydroxylase, isoform CRA_a [Homo sapiens];NP_001310012.1//phytanoyl-CoA dioxygenase, peroxisomal isoform d precursor [Homo sapiens];NP_001310011.1//phytanoyl-CoA dioxygenase, peroxisomal isoform c precursor [Homo sapiens];EHH18893.1//hypothetical protein EGK_19462, partial [Macaca mulatta]","1//3;3//A2MP1"]
[6489,9737,0.27,0.24,-0.169925001442312,0.732964755956785,"*",0.620088,"ST8SIA1","GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0008373//sialyltransferase activity;GO:0003828//alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity","GO:0006486//protein glycosylation;GO:0006665//sphingolipid metabolic process;GO:0034605//cellular response to heat;GO:0008284//positive regulation of cell proliferation","K03371//alpha-N-acetyl-neuraminate alpha-2,8-sialyltransferase (sialyltransferase 8A) [EC:2.4.99.8]","XP_016778110.1//PREDICTED: alpha-N-acetylneuraminide alpha-2,8-sialyltransferase isoform X1 [Pan troglodytes];XP_001099511.1//PREDICTED: alpha-N-acetylneuraminide alpha-2,8-sialyltransferase isoform X1 [Macaca mulatta]","1//3;3//A2MP1"]
[4045,9508,0.18,0.16,-0.169925001442312,0.749359013310185,"*",0.6485,"LSAMP","GO:0005886//plasma membrane;GO:0031225//anchored component of membrane","NA","GO:0007155//cell adhesion;GO:0035641//locomotory exploration behavior","K06772//limbic system-associated membrane protein","XP_006905544.1//PREDICTED: limbic system-associated membrane protein isoform X1 [Pteropus alecto];XP_008841101.1//PREDICTED: limbic system-associated membrane protein isoform X4 [Nannospalax galili]","1//3;4"]
[7515,2102,28.92,25.71,-0.169737942117462,0.0662001395348837,"*",0.029047,"XRCC1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000784//nuclear chromosome, telomeric region;GO:0005730//nucleolus;GO:0070522//ERCC4-ERCC1 complex;GO:0000790//nuclear chromatin","GO:1990599//3' overhang single-stranded DNA endodeoxyribonuclease activity;GO:0003684//damaged DNA binding;GO:0003909//DNA ligase activity;GO:0032356//oxidized DNA binding;GO:0019899//enzyme binding","GO:0006284//base-excision repair;GO:0021766//hippocampus development;GO:0006283//transcription-coupled nucleotide-excision repair;GO:1903518//positive regulation of single strand break repair;GO:0010836//negative regulation of protein ADP-ribosylation;GO:1904877//positive regulation of DNA ligase activity;GO:0010033//response to organic substance;GO:0006288//base-excision repair, DNA ligation;GO:1905765//negative regulation of protection from non-homologous end joining at telomere;GO:0000012//single strand break repair;GO:0042493//response to drug;GO:0061819//telomeric DNA-containing double minutes formation;GO:0001666//response to hypoxia;GO:0006297//nucleotide-excision repair, DNA gap filling;GO:0000724//double-strand break repair via homologous recombination;GO:0006303//double-strand break repair via nonhomologous end joining","K10803//DNA-repair protein XRCC1","BAD92018.1//X-ray repair cross complementing protein 1 variant, partial [Homo sapiens]","2//1"]
[55589,2879,3.35,2.98,-0.168848764882973,0.183985109,"*",0.0967494,"BMP2K","GO:0016607//nuclear speck;GO:0005737//cytoplasm","GO:0035612//AP-2 adaptor complex binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0019208//phosphatase regulator activity","GO:0030500//regulation of bone mineralization;GO:0045747//positive regulation of Notch signaling pathway;GO:2000369//regulation of clathrin-dependent endocytosis;GO:0006468//protein phosphorylation","K08854//BMP2 inducible kinase [EC:2.7.11.1]","XP_011797184.1//PREDICTED: BMP-2-inducible protein kinase [Colobus angolensis palliatus];NP_942595.1//BMP-2-inducible protein kinase isoform a [Homo sapiens]","1//3;3//A2MP1"]
[9757,8490,26.25,23.36,-0.16827714856083,0.000122823449772788,"*",{"v":2.87644e-05,"d":"2.88E-05"},"KMT2B","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0035097//histone methyltransferase complex","GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0042800//histone methyltransferase activity (H3-K4 specific);GO:0003700//DNA binding transcription factor activity;GO:0018024//histone-lysine N-methyltransferase activity","GO:0016458//gene silencing;GO:0051569//regulation of histone H3-K4 methylation;GO:0009994//oocyte differentiation;GO:0048096//chromatin-mediated maintenance of transcription;GO:0006351//transcription, DNA-templated;GO:0051568//histone H3-K4 methylation;GO:0045652//regulation of megakaryocyte differentiation;GO:0030728//ovulation;GO:0001541//ovarian follicle development;GO:0007613//memory;GO:0080182//histone H3-K4 trimethylation","K14959//histone-lysine N-methyltransferase MLL4 [EC:2.1.1.43]","NP_055542.1//histone-lysine N-methyltransferase 2B [Homo sapiens]","2//1"]
[221060,1785,88.84,79.07,-0.168078968234821,0.00170096453892216,"*",0.000497916,"C10orf111","GO:0016021//integral component of membrane","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K11447//histone demethylase [EC:1.14.11.-];K00134//glyceraldehyde 3-phosphate dehydrogenase [EC:1.2.1.12];K01064//wingless-type MMTV integration site family, member 9","EAW86242.1//hCG2017590 [Homo sapiens]","1//3"]
[55164,2861,8.22,7.32,-0.167294745397641,0.309482910190275,"*",0.1832796,"SHQ1","GO:0005654//nucleoplasm;GO:0005829//cytosol","NA","GO:1904874//positive regulation of telomerase RNA localization to Cajal body;GO:2000233//negative regulation of rRNA processing;GO:0043065//positive regulation of apoptotic process;GO:0022618//ribonucleoprotein complex assembly","K14764//protein SHQ1","AAH47879.1//SHQ1 homolog (S. cerevisiae) [Homo sapiens]","2//1"]
[1773,3108,1.92,1.71,-0.167109985835258,0.630008110869565,"*",0.507982,"DNASE1","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005576//extracellular region","GO:0003779//actin binding;GO:0004530//deoxyribonuclease I activity","GO:0006308//DNA catabolic process;GO:0006915//apoptotic process","K11994//deoxyribonuclease-1 [EC:3.1.21.1]","NP_005214.2//deoxyribonuclease-1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[11060,3905,13.21,11.77,-0.166516146208384,0.0132860963388169,"*",0.00475252,"WWP2","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0000151//ubiquitin ligase complex;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0001190//transcriptional activator activity, RNA polymerase II transcription factor binding;GO:0061630//ubiquitin protein ligase activity;GO:0008134//transcription factor binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity","GO:0070534//protein K63-linked ubiquitination;GO:0016567//protein ubiquitination;GO:0043433//negative regulation of DNA binding transcription factor activity;GO:0051224//negative regulation of protein transport;GO:0010629//negative regulation of gene expression;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0051865//protein autoubiquitination;GO:0042391//regulation of membrane potential;GO:0045892//negative regulation of transcription, DNA-templated;GO:0034765//regulation of ion transmembrane transport;GO:0006858//extracellular transport;GO:0032410//negative regulation of transporter activity;GO:1901016//regulation of potassium ion transmembrane transporter activity;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0006464//cellular protein modification process;GO:0046718//viral entry into host cell","K05630//atrophin-1 interacting protein 2 (WW domain containing E3 ubiquitin protein ligase 2) [EC:2.3.2.26]","NP_008945.2//NEDD4-like E3 ubiquitin-protein ligase WWP2 isoform WWP2-FL [Homo sapiens]","4;1//3;2//1"]
[84259,12741,3.03,2.7,-0.16635838642212,0.168559257198208,"*",0.0871498,"DCUN1D5","GO:0000151//ubiquitin ligase complex","GO:0032182//ubiquitin-like protein binding;GO:0097602//cullin family protein binding;GO:0031624//ubiquitin conjugating enzyme binding","GO:0045116//protein neddylation;GO:0051443//positive regulation of ubiquitin-protein transferase activity","K17824//DCN1-like protein 4/5","XP_019467790.1//PREDICTED: DCN1-like protein 5 isoform X2 [Meleagris gallopavo];XP_008147432.1//PREDICTED: DCN1-like protein 5 isoform X1 [Eptesicus fuscus];NP_115675.1//DCN1-like protein 5 isoform a [Homo sapiens]","1//3;3//A2MP1"]
[259,1450,1.57,1.4,-0.165337731946661,0.782893094428236,"*",0.688744,"AMBP","GO:0043231//intracellular membrane-bounded organelle;GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0009986//cell surface;GO:0072562//blood microparticle;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0020037//heme binding;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0019855//calcium channel inhibitor activity;GO:0019862//IgA binding;GO:0042803//protein homodimerization activity;GO:0036094//small molecule binding;GO:0046904//calcium oxalate binding","GO:0007565//female pregnancy;GO:0016032//viral process;GO:0018298//protein-chromophore linkage;GO:0030163//protein catabolic process;GO:0042167//heme catabolic process;GO:0007155//cell adhesion;GO:0050777//negative regulation of immune response;GO:0046329//negative regulation of JNK cascade;GO:0006898//receptor-mediated endocytosis","K03909//tissue factor pathway inhibitor","NP_001624.1//protein AMBP preproprotein [Homo sapiens]","3//A2MP1"]
[8622,4260,1.02,0.91,-0.164630701772799,0.536938395857105,"*",0.382956,"PDE8B","GO:0005829//cytosol","GO:0046872//metal ion binding;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0004115//3',5'-cyclic-AMP phosphodiesterase activity","GO:0009187//cyclic nucleotide metabolic process;GO:0006198//cAMP catabolic process;GO:0007165//signal transduction;GO:0046676//negative regulation of insulin secretion","K18437//high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:3.1.4.53]","NP_001025025.1//high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform 2 [Homo sapiens];NP_001336680.1//high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform 9 [Homo sapiens];NP_001025024.1//high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform 4 [Homo sapiens];NP_001336681.1//high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform 10 [Homo sapiens];NP_001025022.1//high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform 3 [Homo sapiens];NP_001336677.1//high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform 6 [Homo sapiens];NP_001336679.1//high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform 8 [Homo sapiens];NP_001025023.1//high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform 5 [Homo sapiens];NP_003710.1//high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform 1 [Homo sapiens];NP_001336678.1//high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform 7 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[79709,3724,48.71,43.48,-0.163866042813139,0.000901408025276461,"*",0.00025004,"COLGALT1","NA","GO:0016740//transferase activity","NA","K11703//collagen beta-1,O-galactosyltransferase [EC:2.4.1.50]","XP_003123541.1//procollagen galactosyltransferase 1 [Sus scrofa]","3//A2MP1"]
[51643,1878,11.86,10.59,-0.163401420553667,0.308897140499365,"*",0.182778,"TMBIM4","GO:0005795//Golgi stack;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","NA","GO:0050848//regulation of calcium-mediated signaling;GO:0043066//negative regulation of apoptotic process;GO:0006915//apoptotic process","K06890//uncharacterized protein","XP_011784644.1//PREDICTED: protein lifeguard 4 isoform X1 [Colobus angolensis palliatus];NP_001269539.1//protein lifeguard 4 isoform d [Homo sapiens];NP_001269535.1//protein lifeguard 4 isoform a [Homo sapiens]","1//3;3//A2MP1"]
[9026,4314,5.25,4.69,-0.162729500038109,0.444797912457912,"*",0.29772,"HIP1R","GO:0005938//cell cortex;GO:0016324//apical plasma membrane;GO:0032587//ruffle membrane;GO:0043025//neuronal cell body;GO:0005829//cytosol;GO:0030665//clathrin-coated vesicle membrane;GO:0005739//mitochondrion;GO:0043197//dendritic spine;GO:0005856//cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0032839//dendrite cytoplasm;GO:0030136//clathrin-coated vesicle;GO:0014069//postsynaptic density;GO:0048471//perinuclear region of cytoplasm;GO:0097060//synaptic membrane;GO:0005905//clathrin-coated pit","GO:0051015//actin filament binding;GO:0030276//clathrin binding;GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0035091//phosphatidylinositol binding;GO:0003779//actin binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0080025//phosphatidylinositol-3,5-bisphosphate binding;GO:0035615//clathrin adaptor activity;GO:0017124//SH3 domain binding;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding;GO:0032051//clathrin light chain binding","GO:0030100//regulation of endocytosis;GO:0032956//regulation of actin cytoskeleton organization;GO:0032092//positive regulation of protein binding;GO:0043065//positive regulation of apoptotic process;GO:0055123//digestive system development;GO:0048268//clathrin coat assembly;GO:0045742//positive regulation of epidermal growth factor receptor signaling pathway;GO:0060453//regulation of gastric acid secretion;GO:0034316//negative regulation of Arp2/3 complex-mediated actin nucleation;GO:0072583//clathrin-dependent endocytosis;GO:2000588//positive regulation of platelet-derived growth factor receptor-beta signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0006915//apoptotic process;GO:0061024//membrane organization;GO:0030837//negative regulation of actin filament polymerization;GO:1901030//positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway;GO:0006898//receptor-mediated endocytosis;GO:2000369//regulation of clathrin-dependent endocytosis;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0050821//protein stabilization;GO:1905445//positive regulation of clathrin coat assembly","K20040//huntingtin-interacting protein 1-related protein","NP_003950.1//huntingtin-interacting protein 1-related protein isoform 1 [Homo sapiens];NP_001290028.1//huntingtin-interacting protein 1-related protein isoform 3 [Homo sapiens];NP_001290026.1//huntingtin-interacting protein 1-related protein isoform 2 [Homo sapiens]","1//3;2//1"]
[314,2696,1.6,1.43,-0.162056758108973,0.679264152144264,"*",0.56122,"AOC2","GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0009055//electron transfer activity;GO:0052594//aminoacetone:oxygen oxidoreductase(deaminating) activity;GO:0008131//primary amine oxidase activity;GO:0005507//copper ion binding;GO:0048038//quinone binding;GO:0052596//phenethylamine:oxygen oxidoreductase (deaminating) activity;GO:0052595//aliphatic-amine oxidase activity;GO:0052593//tryptamine:oxygen oxidoreductase (deaminating) activity","GO:0006805//xenobiotic metabolic process;GO:0007601//visual perception;GO:0009308//amine metabolic process;GO:0006584//catecholamine metabolic process","K00276//primary-amine oxidase [EC:1.4.3.21]","NP_033720.2//retina-specific copper amine oxidase isoform b precursor [Homo sapiens];NP_001149.2//retina-specific copper amine oxidase isoform a precursor [Homo sapiens]","4;3//A2MP1"]
[7710,6914,0.85,0.76,-0.161463422694116,0.629959200993712,"*",0.507982,"ZNF154","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","ELK17771.1//Zinc finger protein 551 [Pteropus alecto]","2//1"]
[4645,9520,1.42,1.27,-0.161062432732516,0.480133050838142,"*",0.328134,"MYO5B","GO:0070062//extracellular exosome;GO:0045179//apical cortex;GO:0043234//protein complex;GO:0016459//myosin complex;GO:0030659//cytoplasmic vesicle membrane","GO:0003779//actin binding;GO:0005524//ATP binding;GO:0003774//motor activity;GO:0000146//microfilament motor activity;GO:0005516//calmodulin binding;GO:0017137//Rab GTPase binding","GO:0032439//endosome localization;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0003091//renal water homeostasis","K10357//myosin V","NP_001073936.1//unconventional myosin-Vb [Homo sapiens]","2//1"]
[30846,3601,95.41,85.35,-0.160749330947713,{"v":4.0702452470024e-06,"d":"4.07E-06"},"*",{"v":7.43774E-7,"d":"7.44E-07"},"EHD2","GO:0070062//extracellular exosome;GO:0010008//endosome membrane;GO:0005634//nucleus;GO:0015630//microtubule cytoskeleton;GO:0019898//extrinsic component of membrane;GO:0048471//perinuclear region of cytoplasm;GO:0045171//intercellular bridge;GO:0055038//recycling endosome membrane;GO:0005901//caveola;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0019904//protein domain specific binding;GO:0016787//hydrolase activity;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0005509//calcium ion binding;GO:0005525//GTP binding;GO:0003676//nucleic acid binding","GO:0072659//protein localization to plasma membrane;GO:0007596//blood coagulation;GO:2001137//positive regulation of endocytic recycling;GO:0030866//cortical actin cytoskeleton organization;GO:0006897//endocytosis;GO:0032456//endocytic recycling;GO:0097320//plasma membrane tubulation;GO:1901741//positive regulation of myoblast fusion","K12469//EH domain-containing protein 2","NP_055416.2//EH domain-containing protein 2 [Homo sapiens]","3//A2MP1"]
[117584,4137,21.3,19.06,-0.160305311203259,0.0308360763992419,"*",0.01222324,"RFFL","NA","NA","NA","K20804//E3 ubiquitin-protein ligase RNF34 [EC:2.3.2.27]","XP_004441925.2//PREDICTED: E3 ubiquitin-protein ligase rififylin isoform X1 [Ceratotherium simum simum]","1//3"]
[10090,4396,2.48,2.22,-0.159780444036769,0.549709416768346,"*",0.394852,"UST","GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0008146//sulfotransferase activity","GO:0030010//establishment of cell polarity;GO:0030208//dermatan sulfate biosynthetic process;GO:0006477//protein sulfation;GO:0050770//regulation of axonogenesis","K03193//dermatan/chondrotin sulfate uronyl 2-O-sulfotransferase UST [EC:2.8.2.-]","NP_005706.1//uronyl 2-sulfotransferase [Homo sapiens]","2//1"]
[8526,7784,1.82,1.63,-0.159066485967619,0.491859184215312,"*",0.338642,"DGKE","GO:0016020//membrane;GO:0005634//nucleus;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0004143//diacylglycerol kinase activity;GO:0003951//NAD+ kinase activity;GO:0046872//metal ion binding;GO:0005524//ATP binding;GO:0016301//kinase activity","GO:0008654//phospholipid biosynthetic process;GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0030168//platelet activation;GO:0035556//intracellular signal transduction;GO:0046834//lipid phosphorylation","K00901//diacylglycerol kinase (ATP) [EC:2.7.1.107]","XP_011523696.1//PREDICTED: diacylglycerol kinase epsilon isoform X2 [Homo sapiens]","2//1"]
[22832,5119,0.48,0.43,-0.158697746019058,0.794152426534933,"*",0.704466,"CEP162","GO:0005814//centriole;GO:0005879//axonemal microtubule;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005819//spindle;GO:0005813//centrosome","NA","GO:0060271//cilium assembly;GO:0097711//ciliary basal body-plasma membrane docking","K16809//protein QN1","NP_055710.2//centrosomal protein of 162 kDa isoform a [Homo sapiens]","1//3;3//A2MP1"]
[10536,2690,12.51,11.21,-0.158295511360393,0.227810106936937,"*",0.1266404,"P3H3","GO:0005783//endoplasmic reticulum;GO:1902494//catalytic complex","GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0019797//procollagen-proline 3-dioxygenase activity;GO:0005506//iron ion binding;GO:0031418//L-ascorbic acid binding","GO:0032963//collagen metabolic process;GO:0017185//peptidyl-lysine hydroxylation;GO:0008285//negative regulation of cell proliferation;GO:0032964//collagen biosynthetic process","K08440//G protein-coupled receptor 162;K08134//leucine proline-enriched proteoglycan (leprecan)","XP_015006419.1//PREDICTED: prolyl 3-hydroxylase 3 [Macaca mulatta]",4]
[55139,2521,6.97,6.25,-0.157302466318974,0.36753430989899,"*",0.227782,"ANKZF1","GO:0016020//membrane;GO:0036266//Cdc48p-Npl4p-Vms1p AAA ATPase complex;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0003676//nucleic acid binding","GO:0072671//mitochondria-associated ubiquitin-dependent protein catabolic process;GO:0071630//nuclear protein quality control by the ubiquitin-proteasome system;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0070301//cellular response to hydrogen peroxide","NA","NP_060559.2//ankyrin repeat and zinc finger domain-containing protein 1 isoform 1 [Homo sapiens];XP_005246720.1//PREDICTED: ankyrin repeat and zinc finger domain-containing protein 1 isoform X2 [Homo sapiens]","1//3;2//1"]
[442213,3268,3.78,3.39,-0.157100961084729,0.515887883818915,"*",0.360256,"PTCHD4","GO:0016021//integral component of membrane","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K12385//Niemann-Pick C1 protein;K07560//D-tyrosyl-tRNA(Tyr) deacylase [EC:3.1.-.-];K16506//protocadherin Fat 1/2/3;K14461//Niemann-Pick C1-like protein 1;K04487//cysteine desulfurase [EC:2.8.1.7]","NP_001013754.3//patched domain-containing protein 4 isoform 1 [Homo sapiens];NP_997382.2//patched domain-containing protein 4 isoform 2 [Homo sapiens]","3//A2MP1;2//1"]
[54884,3328,14.9,13.37,-0.156312865256171,0.136385062890232,"*",0.0678254,"RETSAT","GO:0016020//membrane;GO:0031965//nuclear membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005640//nuclear outer membrane","GO:0051786//all-trans-retinol 13,14-reductase activity;GO:0016491//oxidoreductase activity","GO:0042572//retinol metabolic process;GO:0055114//oxidation-reduction process","K09516//all-trans-retinol 13,14-reductase [EC:1.3.99.23]","NP_060220.3//all-trans-retinol 13,14-reductase precursor [Homo sapiens]","3//A2MP1"]
[10552,1623,63.29,56.81,-0.155832664760925,0.0243124020471162,"*",0.0093679,"ARPC1A","GO:0070062//extracellular exosome;GO:0005885//Arp2/3 protein complex;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0036195//muscle cell projection membrane","GO:0051015//actin filament binding;GO:0003779//actin binding","GO:0034314//Arp2/3 complex-mediated actin nucleation;GO:0030036//actin cytoskeleton organization;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0048013//ephrin receptor signaling pathway;GO:0061024//membrane organization","K05757//actin related protein 2/3 complex, subunit 1A/1B","NP_001177925.1//actin-related protein 2/3 complex subunit 1A isoform 2 [Homo sapiens];BAD92296.1//actin related protein 2/3 complex subunit 1A variant, partial [Homo sapiens]","1//3;3//A2MP1"]
[81575,4752,0.59,0.53,-0.154722594798642,0.733973547400612,"*",0.63105,"APOLD1","GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0008289//lipid binding","GO:0030154//cell differentiation;GO:0001525//angiogenesis;GO:0006869//lipid transport;GO:0042118//endothelial cell activation;GO:0045601//regulation of endothelial cell differentiation;GO:0042157//lipoprotein metabolic process;GO:0001666//response to hypoxia","K14777//ATP-dependent RNA helicase DDX47/RRP3 [EC:3.6.4.13];K14480//apolipoprotein L","AAH42478.1//APOLD1 protein, partial [Homo sapiens];NP_110444.3//apolipoprotein L domain-containing protein 1 isoform 2 [Homo sapiens]","1//3;2//1"]
[54584,1537,7.09,6.37,-0.154492254983216,0.582489055788842,"*",0.425508,"GNB1L","GO:0009898//cytoplasmic side of plasma membrane;GO:0005737//cytoplasm","NA","GO:0007186//G-protein coupled receptor signaling pathway;GO:0035176//social behavior;GO:0035556//intracellular signal transduction","K19760//dynein assembly factor with WDR repeat domains 1;K18643//katanin p80 WD40 repeat-containing subunit B1","NP_443730.1//guanine nucleotide-binding protein subunit beta-like protein 1 [Homo sapiens]","2//1"]
[79912,4245,8.82,7.93,-0.153457789853542,0.259216621505376,"*",0.1478966,"PYROXD1","GO:0005634//nucleus;GO:0030017//sarcomere","GO:0016491//oxidoreductase activity","GO:0034599//cellular response to oxidative stress","K10899//ATP-dependent DNA helicase Q1 [EC:3.6.4.12];K16174//small subunit ribosomal protein S18b, mitochondrial","NP_079130.2//pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 isoform 1 [Homo sapiens]","1//3;4"]
[81614,3111,42.26,38.01,-0.152913742072975,0.00288626225509372,"*",0.000886802,"NIPA2","GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005769//early endosome","GO:0015095//magnesium ion transmembrane transporter activity","GO:0015693//magnesium ion transport","K19364//magnesium transporter NIPA1","NP_001008894.1//magnesium transporter NIPA2 isoform b [Homo sapiens];NP_001008860.1//magnesium transporter NIPA2 isoform a [Homo sapiens]","6;1//3;2//1"]
[131076,734,26.45,23.8,-0.152306148806082,0.426182858283433,"*",0.280698,"CCDC58","GO:0005739//mitochondrion","NA","NA","K16741//alstrom syndrome protein 1","NP_001295255.1//coiled-coil domain-containing protein 58 isoform 2 [Homo sapiens];XP_004873654.2//coiled-coil domain-containing protein 58 isoform X1 [Heterocephalus glaber]","1//3;3//A2MP1"]
[7718,2411,0.7,0.63,-0.15200309344505,0.836479341004617,"*",0.759974,"ZNF165","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","XP_006215316.1//PREDICTED: zinc finger protein 165 [Vicugna pacos]","3//A2MP1"]
[246330,2634,6.7,6.03,-0.15200309344505,0.51640819360043,"*",0.360684,"PELI3","GO:0005829//cytosol","GO:0061630//ubiquitin protein ligase activity;GO:0004674//protein serine/threonine kinase activity;GO:0016874//ligase activity","GO:0070534//protein K63-linked ubiquitination;GO:0010804//negative regulation of tumor necrosis factor-mediated signaling pathway;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:0008063//Toll signaling pathway;GO:0006955//immune response","K11964//pellino [EC:2.3.2.27]","NP_001091980.1//E3 ubiquitin-protein ligase pellino homolog 3 isoform 2 [Homo sapiens];OWK17375.1//hypothetical protein Celaphus_00013231, partial [Cervus elaphus hippelaphus];NP_659502.2//E3 ubiquitin-protein ligase pellino homolog 3 isoform 1 [Homo sapiens];NP_001230064.1//E3 ubiquitin-protein ligase pellino homolog 3 isoform 3 [Homo sapiens]","1//3;2//1"]
[1500,5804,47.28,42.58,-0.151054085725239,{"v":6.80345100038745e-07,"d":"6.80E-07"},"*",{"v":1.099268E-7,"d":"1.10E-07"},"CTNND1","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005915//zonula adherens;GO:0030027//lamellipodium;GO:0005737//cytoplasm;GO:0030496//midbody;GO:0030426//growth cone;GO:0005911//cell-cell junction;GO:0005829//cytosol;GO:0043197//dendritic spine;GO:0005886//plasma membrane","GO:0005102//receptor binding;GO:0019901//protein kinase binding;GO:0045296//cadherin binding","GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0007155//cell adhesion;GO:0034332//adherens junction organization;GO:0006355//regulation of transcription, DNA-templated;GO:0035635//entry of bacterium into host cell;GO:0016055//Wnt signaling pathway;GO:0006351//transcription, DNA-templated;GO:0007420//brain development","K05690//catenin (cadherin-associated protein), delta 1","NP_001078927.1//catenin delta-1 isoform 1ABC [Homo sapiens];NP_001078928.1//catenin delta-1 isoform 1AB [Homo sapiens];NP_001193814.1//catenin delta-1 isoform 1AC [Homo sapiens];NP_001193812.1//catenin delta-1 isoform 2ABC [Homo sapiens];XP_007996293.1//PREDICTED: catenin delta-1 isoform X8 [Chlorocebus sabaeus];NP_001078929.1//catenin delta-1 isoform 1A [Homo sapiens];NP_001193817.1//catenin delta-1 isoform 2A [Homo sapiens];NP_001322.1//catenin delta-1 isoform 1B [Homo sapiens];NP_001193813.1//catenin delta-1 isoform 2AC [Homo sapiens]","1//3;2//1"]
[60412,4203,13.97,12.59,-0.150053737690447,0.117648843834901,"*",0.0563866,"EXOC4","GO:0016020//membrane;GO:0005902//microvillus;GO:0005737//cytoplasm;GO:0030496//midbody;GO:0032584//growth cone membrane;GO:0035748//myelin sheath abaxonal region;GO:0000145//exocyst;GO:0005829//cytosol;GO:0045202//synapse;GO:0005886//plasma membrane","GO:0047485//protein N-terminus binding;GO:0017160//Ral GTPase binding;GO:0030165//PDZ domain binding","GO:0016241//regulation of macroautophagy;GO:0006612//protein targeting to membrane;GO:0006903//vesicle targeting;GO:0006904//vesicle docking involved in exocytosis;GO:0048341//paraxial mesoderm formation;GO:0007268//chemical synaptic transmission;GO:0006893//Golgi to plasma membrane transport;GO:0006887//exocytosis","K06111//exocyst complex component 4","XP_011851219.1//PREDICTED: exocyst complex component 4 isoform X3 [Mandrillus leucophaeus];NP_068579.3//exocyst complex component 4 isoform a [Homo sapiens]","1//3;3//A2MP1"]
[2135,3174,4.05,3.65,-0.150025444004607,0.529408946692815,"*",0.371786,"EXTL2","GO:0070062//extracellular exosome;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0047237//glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity;GO:0035248//alpha-1,4-N-acetylgalactosaminyltransferase activity;GO:0016757//transferase activity, transferring glycosyl groups;GO:0005539//glycosaminoglycan binding;GO:0001888//glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity;GO:0030145//manganese ion binding","GO:0006044//N-acetylglucosamine metabolic process;GO:0036498//IRE1-mediated unfolded protein response;GO:0015012//heparan sulfate proteoglycan biosynthetic process;GO:0019276//UDP-N-acetylgalactosamine metabolic process","K02369//alpha-1,4-N-acetylglucosaminyltransferase EXTL2 [EC:2.4.1.223]","NP_001430.1//exostosin-like 2 isoform 1 [Homo sapiens];NP_001248369.1//exostosin-like 2 isoform 2 [Homo sapiens];NP_001248370.1//exostosin-like 2 isoform 3 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[56172,8231,3.46,3.12,-0.149226008774476,0.302574651904,"*",0.1775784,"ANKH","GO:0005887//integral component of plasma membrane","GO:0015114//phosphate ion transmembrane transporter activity;GO:0005315//inorganic phosphate transmembrane transporter activity;GO:0030504//inorganic diphosphate transmembrane transporter activity","GO:0030500//regulation of bone mineralization","K01368//cathepsin S [EC:3.4.22.27];K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9]","XP_011757635.1//PREDICTED: progressive ankylosis protein homolog [Macaca nemestrina]",5]
[221785,4285,4.49,4.05,-0.14879353696916,0.494925614748888,"*",0.341156,"ZSCAN25","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein;K09229//KRAB and SCAN domains-containing zinc finger protein","XP_012614902.1//zinc finger and SCAN domain-containing protein 25 isoform X1 [Microcebus murinus];XP_006942015.1//PREDICTED: zinc finger and SCAN domain-containing protein 25 isoform X1 [Felis catus];NP_001337914.1//zinc finger and SCAN domain-containing protein 25 isoform c [Homo sapiens];XP_012310967.1//zinc finger and SCAN domain-containing protein 25 isoform X1 [Aotus nancymaae]","1//3;2//1"]
[3581,2171,0.41,0.37,-0.148098638989134,0.895972586544917,"*",0.835396,"IL9R","GO:0005615//extracellular space;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004919//interleukin-9 receptor activity;GO:0004896//cytokine receptor activity;GO:0019983//interleukin-9 binding","GO:0007165//signal transduction;GO:0008283//cell proliferation;GO:1903955//positive regulation of protein targeting to mitochondrion;GO:0030307//positive regulation of cell growth","K05073//interleukin 9 receptor","NP_002177.2//interleukin-9 receptor isoform 1 precursor [Homo sapiens];NP_789743.2//interleukin-9 receptor isoform 2 [Homo sapiens]","1//3;2//1"]
[51103,1488,4.52,4.08,-0.147753620443692,0.654470665745856,"*",0.533934,"NDUFAF1","GO:0005747//mitochondrial respiratory chain complex I;GO:0005829//cytosol;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0051082//unfolded protein binding","GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0006461//protein complex assembly","K18159//NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1","NP_057097.2//complex I intermediate-associated protein 30, mitochondrial precursor [Homo sapiens]","3//A2MP1"]
[54996,2158,4.23,3.82,-0.147085025084201,0.471975395545739,"*",0.321052,"2019-03-02","GO:0070062//extracellular exosome;GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane;GO:0005777//peroxisome;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane","GO:0043546//molybdopterin cofactor binding;GO:0008940//nitrate reductase activity;GO:0030151//molybdenum ion binding;GO:0003824//catalytic activity;GO:0030170//pyridoxal phosphate binding","GO:0006805//xenobiotic metabolic process;GO:0042126//nitrate metabolic process;GO:0055114//oxidation-reduction process;GO:0051410//detoxification of nitrogen compound","K15631//molybdenum cofactor sulfurtransferase [EC:2.8.1.9]","NP_001317971.1//mitochondrial amidoxime reducing component 2 isoform b precursor [Homo sapiens];NP_060368.2//mitochondrial amidoxime reducing component 2 isoform a precursor [Homo sapiens]","4;1//3"]
[7458,2495,171.57,154.99,-0.14662217597751,{"v":2.64139604383174e-06,"d":"2.64E-06"},"*",{"v":4.67792e-07,"d":"4.68E-07"},"EIF4H","GO:0016020//membrane;GO:0005829//cytosol;GO:0005844//polysome;GO:0048471//perinuclear region of cytoplasm;GO:0016281//eukaryotic translation initiation factor 4F complex","GO:0008135//translation factor activity, RNA binding;GO:0003723//RNA binding;GO:0043024//ribosomal small subunit binding;GO:0004386//helicase activity;GO:0045296//cadherin binding;GO:0034057//RNA strand-exchange activity;GO:0003743//translation initiation factor activity;GO:0033592//RNA strand annealing activity","GO:0006413//translational initiation;GO:0019953//sexual reproduction;GO:0006446//regulation of translational initiation;GO:0097010//eukaryotic translation initiation factor 4F complex assembly;GO:0048589//developmental growth;GO:0016032//viral process;GO:0001731//formation of translation preinitiation complex","K03258//translation initiation factor 4B","XP_527788.4//PREDICTED: eukaryotic translation initiation factor 4H [Pan troglodytes];NP_071496.1//eukaryotic translation initiation factor 4H isoform 1 [Homo sapiens]","1//3"]
[80314,4093,4.57,4.13,-0.146052383638624,0.458952996755354,"*",0.309924,"EPC1","GO:0035267//NuA4 histone acetyltransferase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0032777//Piccolo NuA4 histone acetyltransferase complex","GO:0004402//histone acetyltransferase activity","GO:0045892//negative regulation of transcription, DNA-templated;GO:0040008//regulation of growth;GO:0043968//histone H2A acetylation;GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0043967//histone H4 acetylation;GO:0045814//negative regulation of gene expression, epigenetic;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0035886//vascular smooth muscle cell differentiation","K11322//enhancer of polycomb-like protein","XP_008064686.1//enhancer of polycomb homolog 1 isoform X3 [Carlito syrichta];NP_001258933.1//enhancer of polycomb homolog 1 isoform b [Homo sapiens];NP_001269320.1//enhancer of polycomb homolog 1 isoform d [Homo sapiens];XP_021798854.1//LOW QUALITY PROTEIN: enhancer of polycomb homolog 1 [Papio anubis]","1//3;3//A2MP1;2//1"]
[85315,4758,0.73,0.66,-0.145430439521564,0.765499317199282,"*",0.667308,"PAQR8","GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0003707//steroid hormone receptor activity;GO:0005496//steroid binding","GO:0048545//response to steroid hormone;GO:0048477//oogenesis;GO:0007275//multicellular organism development","K02927//large subunit ribosomal protein L40e;K15696//RING finger protein 113B;K17985//activating molecule in BECN1-regulated autophagy protein 1;K07297//adiponectin receptor","XP_003254205.2//PREDICTED: membrane progestin receptor beta [Nomascus leucogenys]",4]
[6832,2483,15.57,14.08,-0.14512161044174,0.244215993465941,"*",0.1375798,"SUPV3L1","GO:0005759//mitochondrial matrix;GO:0045025//mitochondrial degradosome;GO:0005634//nucleus;GO:0042645//mitochondrial nucleoid;GO:0005739//mitochondrion","GO:0003723//RNA binding;GO:0003677//DNA binding;GO:0005524//ATP binding;GO:0034458//3'-5' RNA helicase activity;GO:0004386//helicase activity;GO:0042803//protein homodimerization activity;GO:0003725//double-stranded RNA binding;GO:0016817//hydrolase activity, acting on acid anhydrides;GO:0004004//ATP-dependent RNA helicase activity;GO:0003678//DNA helicase activity","GO:0006401//RNA catabolic process;GO:2000827//mitochondrial RNA surveillance;GO:0035945//mitochondrial ncRNA surveillance;GO:0000962//positive regulation of mitochondrial RNA catabolic process;GO:0030307//positive regulation of cell growth;GO:0043066//negative regulation of apoptotic process;GO:0070827//chromatin maintenance;GO:0035946//mitochondrial mRNA surveillance;GO:0032508//DNA duplex unwinding;GO:0070584//mitochondrion morphogenesis;GO:0000965//mitochondrial RNA 3'-end processing;GO:0006310//DNA recombination;GO:0000958//mitochondrial mRNA catabolic process","K17675//ATP-dependent RNA helicase SUPV3L1/SUV3 [EC:3.6.4.13]","NP_001310515.1//ATP-dependent RNA helicase SUPV3L1, mitochondrial isoform 3 [Homo sapiens];NP_003162.2//ATP-dependent RNA helicase SUPV3L1, mitochondrial isoform 1 [Homo sapiens]","1//3;4"]
[3032,2196,37.65,34.05,-0.144995066659857,0.0685915391477273,"*",0.0302294,"HADHB","GO:0005740//mitochondrial envelope;GO:0070062//extracellular exosome;GO:0005783//endoplasmic reticulum;GO:0042645//mitochondrial nucleoid;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane","GO:0003723//RNA binding;GO:0003988//acetyl-CoA C-acyltransferase activity;GO:0016509//long-chain-3-hydroxyacyl-CoA dehydrogenase activity;GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups;GO:0003857//3-hydroxyacyl-CoA dehydrogenase activity;GO:0004300//enoyl-CoA hydratase activity","GO:0006635//fatty acid beta-oxidation;GO:0008152//metabolic process;GO:0035965//cardiolipin acyl-chain remodeling","K07509//acetyl-CoA acyltransferase [EC:2.3.1.16]","NP_001268442.1//trifunctional enzyme subunit beta, mitochondrial isoform 3 [Homo sapiens];NP_001268441.1//trifunctional enzyme subunit beta, mitochondrial isoform 2 precursor [Homo sapiens];NP_000174.1//trifunctional enzyme subunit beta, mitochondrial isoform 1 precursor [Homo sapiens]","1//3;2//1"]
[8857,16407,0.42,0.38,-0.144389909335175,0.712159577723104,"*",0.597984,"FCGBP","GO:0070062//extracellular exosome","NA","NA","K18273//alpha-tectorin","NP_003881.2//IgGFc-binding protein precursor [Homo sapiens]","2//1"]
[55005,2013,4.95,4.48,-0.143929792909368,0.319980987505241,"*",0.1910992,"RMND1","GO:0005739//mitochondrion","NA","GO:0006412//translation;GO:0070131//positive regulation of mitochondrial translation","K21456//glutathione synthase [EC:6.3.2.3]","NP_060379.2//required for meiotic nuclear division protein 1 homolog isoform 1 [Homo sapiens];XP_003811549.1//PREDICTED: required for meiotic nuclear division protein 1 homolog isoform X1 [Pan paniscus]","1//3;3//A2MP1"]
[8417,3966,5.19,4.7,-0.143073781792881,0.0891609600762008,"*",0.0410194,"STX7","GO:0005770//late endosome;GO:0031982//vesicle;GO:0070820//tertiary granule;GO:0012505//endomembrane system;GO:0016021//integral component of membrane;GO:0055037//recycling endosome;GO:0005886//plasma membrane;GO:0005769//early endosome;GO:0042582//azurophil granule;GO:0070062//extracellular exosome;GO:0005765//lysosomal membrane;GO:0005764//lysosome;GO:0001772//immunological synapse;GO:0048471//perinuclear region of cytoplasm;GO:0005768//endosome;GO:0031901//early endosome membrane;GO:0030139//endocytic vesicle;GO:0031201//SNARE complex","GO:0000149//SNARE binding;GO:0005484//SNAP receptor activity;GO:0019869//chloride channel inhibitor activity;GO:0019905//syntaxin binding","GO:0051640//organelle localization;GO:0070925//organelle assembly;GO:0016192//vesicle-mediated transport;GO:1903076//regulation of protein localization to plasma membrane;GO:0006886//intracellular protein transport;GO:0006906//vesicle fusion;GO:1902685//positive regulation of receptor localization to synapse;GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0048278//vesicle docking","K08488//syntaxin 7","NP_001313509.1//syntaxin-7 isoform b [Homo sapiens];NP_003560.2//syntaxin-7 isoform a [Homo sapiens]","1//3;2//1"]
[65985,3309,10.55,9.56,-0.142160475613799,0.181998034021233,"*",0.0955108,"AACS","GO:0005829//cytosol","GO:0030729//acetoacetate-CoA ligase activity;GO:0047760//butyrate-CoA ligase activity;GO:0005524//ATP binding","GO:0032024//positive regulation of insulin secretion;GO:0050872//white fat cell differentiation;GO:0045471//response to ethanol;GO:0006631//fatty acid metabolic process;GO:0007584//response to nutrient;GO:0034201//response to oleic acid;GO:0046951//ketone body biosynthetic process;GO:0042493//response to drug;GO:0071394//cellular response to testosterone stimulus;GO:0001889//liver development;GO:0060612//adipose tissue development;GO:0014074//response to purine-containing compound;GO:0071333//cellular response to glucose stimulus;GO:0071397//cellular response to cholesterol;GO:0042594//response to starvation;GO:0006629//lipid metabolic process","K01907//acetoacetyl-CoA synthetase [EC:6.2.1.16]","NP_076417.2//acetoacetyl-CoA synthetase isoform 1 [Homo sapiens];NP_001306769.1//acetoacetyl-CoA synthetase isoform 3 [Homo sapiens];NP_001306768.1//acetoacetyl-CoA synthetase isoform 2 [Homo sapiens]","4;1//3"]
[9370,4629,0.96,0.87,-0.142019004872428,0.736096304720407,"*",0.634534,"ADIPOQ","NA","NA","NA","K06237//collagen, type IV, alpha","XP_006123490.1//PREDICTED: otolin-1 isoform X2 [Pelodiscus sinensis];XP_006123489.1//PREDICTED: otolin-1 isoform X1 [Pelodiscus sinensis]","1//3;3//A2MP1"]
[132884,4426,1.07,0.97,-0.141554144214019,0.699268115606936,"*",0.583132,"EVC2","GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0060170//ciliary membrane;GO:0005634//nucleus;GO:0016021//integral component of membrane;GO:0098797//plasma membrane protein complex;GO:0005737//cytoplasm","NA","GO:0007224//smoothened signaling pathway","K19608//ellis van creveld syndrome protein 2","NP_001159608.1//limbin isoform 2 [Homo sapiens];XP_001155684.1//PREDICTED: limbin isoform X1 [Pan troglodytes]","1//3;4"]
[5660,2908,249.39,226.18,-0.140932252929329,{"v":2.72181375609756e-09,"d":"2.72E-09"},"*",{"v":3.21356e-10,"d":"3.21E-10"},"PSAP","GO:0005765//lysosomal membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005764//lysosome;GO:0035577//azurophil granule membrane;GO:0005576//extracellular region;GO:0016021//integral component of membrane;GO:0043202//lysosomal lumen;GO:0005739//mitochondrion;GO:0005886//plasma membrane","GO:1905573//ganglioside GM1 binding;GO:0042802//identical protein binding;GO:1905574//ganglioside GM2 binding;GO:0042803//protein homodimerization activity;GO:0005543//phospholipid binding;GO:0008289//lipid binding;GO:1905577//ganglioside GP1c binding;GO:1905576//ganglioside GT1b binding;GO:0004565//beta-galactosidase activity;GO:0001664//G-protein coupled receptor binding;GO:1905575//ganglioside GM3 binding;GO:0008047//enzyme activator activity","GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0006869//lipid transport;GO:0006687//glycosphingolipid metabolic process;GO:0071310//cellular response to organic substance;GO:0060742//epithelial cell differentiation involved in prostate gland development;GO:1903206//negative regulation of hydrogen peroxide-induced cell death;GO:0002576//platelet degranulation;GO:0006665//sphingolipid metabolic process;GO:1905572//ganglioside GM1 transport to membrane;GO:0019216//regulation of lipid metabolic process;GO:0043410//positive regulation of MAPK cascade;GO:0043312//neutrophil degranulation;GO:0010506//regulation of autophagy;GO:0060736//prostate gland growth","K12382//saposin","BAD93013.1//prosaposin variant, partial [Homo sapiens]","3//A2MP1;2//1"]
[5598,2859,18.39,16.68,-0.140802190967274,0.168178342400388,"*",0.0869318,"MAPK7","GO:0016605//PML body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0004674//protein serine/threonine kinase activity;GO:0051019//mitogen-activated protein kinase binding;GO:0005524//ATP binding;GO:0004707//MAP kinase activity","GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0051534//negative regulation of NFAT protein import into nucleus;GO:0043407//negative regulation of MAP kinase activity;GO:0050728//negative regulation of inflammatory response;GO:0071499//cellular response to laminar fluid shear stress;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0030821//negative regulation of cAMP catabolic process;GO:0070377//negative regulation of ERK5 cascade;GO:0071363//cellular response to growth factor stimulus;GO:0007411//axon guidance;GO:0070301//cellular response to hydrogen peroxide;GO:1902176//negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:0060761//negative regulation of response to cytokine stimulus;GO:0007165//signal transduction;GO:0051247//positive regulation of protein metabolic process;GO:0043066//negative regulation of apoptotic process;GO:0036003//positive regulation of transcription from RNA polymerase II promoter in response to stress;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:0019933//cAMP-mediated signaling;GO:0034115//negative regulation of heterotypic cell-cell adhesion;GO:0045765//regulation of angiogenesis;GO:0018105//peptidyl-serine phosphorylation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0051344//negative regulation of cyclic-nucleotide phosphodiesterase activity;GO:0007049//cell cycle","K04464//mitogen-activated protein kinase 7 [EC:2.7.11.24]","XP_008957611.1//PREDICTED: mitogen-activated protein kinase 7 isoform X3 [Pan paniscus];NP_002740.2//mitogen-activated protein kinase 7 isoform 1 [Homo sapiens]","3//A2MP1;2//1"]
[4670,2508,71.23,64.64,-0.140057792197896,0.00362375404112597,"*",0.001136308,"HNRNPM","GO:0016020//membrane;GO:0031012//extracellular matrix;GO:0070062//extracellular exosome;GO:0005654//nucleoplasm;GO:0016363//nuclear matrix;GO:0042382//paraspeckles;GO:0071013//catalytic step 2 spliceosome;GO:0005681//spliceosomal complex;GO:0005887//integral component of plasma membrane;GO:0005730//nucleolus;GO:0019013//viral nucleocapsid","GO:0003723//RNA binding;GO:0019904//protein domain specific binding","GO:0016070//RNA metabolic process;GO:0000398//mRNA splicing, via spliceosome;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0000380//alternative mRNA splicing, via spliceosome","K12887//heterogeneous nuclear ribonucleoprotein M","XP_002761735.2//PREDICTED: heterogeneous nuclear ribonucleoprotein M isoform X5 [Callithrix jacchus];XP_008985392.1//PREDICTED: heterogeneous nuclear ribonucleoprotein M isoform X1 [Callithrix jacchus];BAD92970.1//heterogeneous nuclear ribonucleoprotein M isoform a variant, partial [Homo sapiens]","1//3;4;3//A2MP1"]
[26135,6725,34.97,31.74,-0.139815667862534,0.00117609367710631,"*",0.000333818,"SERBP1","NA","NA","NA","K13199//plasminogen activator inhibitor 1 RNA-binding protein","EAX06490.1//SERPINE1 mRNA binding protein 1, isoform CRA_b [Homo sapiens];EAX06492.1//SERPINE1 mRNA binding protein 1, isoform CRA_d [Homo sapiens];EAX06495.1//SERPINE1 mRNA binding protein 1, isoform CRA_f [Homo sapiens];EAX06491.1//SERPINE1 mRNA binding protein 1, isoform CRA_c [Homo sapiens]","1//3;3//A2MP1"]
[5757,1220,1343.03,1219.46,-0.139249094910679,{"v":5.18764869501823e-19,"d":"5.19E-19"},"*",{"v":2.67274E-20,"d":"2.67E-20"},"PTMA","GO:0016021//integral component of membrane","NA","GO:0007275//multicellular organism development","K19607//X-linked retinitis pigmentosa GTPase regulator","XP_020930232.1//prothymosin alpha isoform X1 [Sus scrofa];ELW63422.1//hypothetical protein TREES_T100016057 [Tupaia chinensis]","4;1//3"]
[51501,1187,17.86,16.22,-0.13895826090395,0.415027874247492,"*",0.271896,"HIKESHI","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005622//intracellular","GO:0008565//protein transporter activity;GO:0030544//Hsp70 protein binding","GO:0030324//lung development;GO:1900034//regulation of cellular response to heat;GO:0006606//protein import into nucleus;GO:0007030//Golgi organization;GO:0015031//protein transport;GO:0034605//cellular response to heat","NA","ELW68942.1//hypothetical protein TREES_T100012980 [Tupaia chinensis];EPQ13581.1//Hypothetical protein D623_10014362 [Myotis brandtii];NP_057485.2//protein Hikeshi isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[140894,2560,3.28,2.98,-0.138383484155922,0.648129819712729,"*",0.491514,"CNBD2","GO:0005829//cytosol","GO:0030552//cAMP binding","GO:0007283//spermatogenesis","K12581//CCR4-NOT transcription complex subunit 7/8;K07376//cGMP-dependent protein kinase 1 [EC:2.7.11.12];K04351//Rap guanine nucleotide exchange factor 4;K17532//STE20-related kinase adapter protein beta;K01064//wingless-type MMTV integration site family, member 9;K19477//cGMP-dependent protein kinase 2 [EC:2.7.11.12]","NP_001291296.1//cyclic nucleotide-binding domain-containing protein 2 isoform 3 [Homo sapiens];NP_543024.2//cyclic nucleotide-binding domain-containing protein 2 isoform 1 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[961,5309,6.37,5.79,-0.137730024267064,0.292634076736447,"*",0.1706452,"CD47","GO:0070062//extracellular exosome;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane;GO:0070821//tertiary granule membrane;GO:0005886//plasma membrane","GO:0070053//thrombospondin receptor activity","GO:0050900//leukocyte migration;GO:0050729//positive regulation of inflammatory response;GO:0022409//positive regulation of cell-cell adhesion;GO:0050870//positive regulation of T cell activation;GO:0050766//positive regulation of phagocytosis;GO:0007155//cell adhesion;GO:0030198//extracellular matrix organization;GO:0007229//integrin-mediated signaling pathway;GO:0043312//neutrophil degranulation;GO:0009617//response to bacterium;GO:0008228//opsonization;GO:0008284//positive regulation of cell proliferation","K06266//CD47 antigen (Rh-related antigen, integrin-associated signal transducer)","NP_001768.1//leukocyte surface antigen CD47 isoform 1 precursor [Homo sapiens];NP_942088.1//leukocyte surface antigen CD47 isoform 2 precursor [Homo sapiens]","3//A2MP1;2//1"]
[6462,1232,0.55,0.5,-0.137503523749935,0.723389255717256,"*",0.609904,"SHBG","GO:0070062//extracellular exosome;GO:0005576//extracellular region","GO:0005497//androgen binding;GO:0005496//steroid binding","NA","K03908//protein S;K05464//growth arrest-specific 6","NP_001276045.1//sex hormone-binding globulin isoform 7 [Homo sapiens];NP_001031.2//sex hormone-binding globulin isoform 1 precursor [Homo sapiens];XP_011907937.1//PREDICTED: sex hormone-binding globulin isoform X5 [Cercocebus atys];XP_011907928.1//PREDICTED: sex hormone-binding globulin isoform X4 [Cercocebus atys];XP_017705956.1//PREDICTED: sex hormone-binding globulin isoform X2 [Rhinopithecus bieti];NP_001270513.1//sex hormone-binding globulin [Macaca fascicularis];CAA34400.1//SHBG related protein (288 AA), partial [Homo sapiens]","1//3;4;2//1"]
[7070,2096,5.17,4.7,-0.137503523749935,0.58522976852168,"*",0.429232,"THY1","GO:0070062//extracellular exosome;GO:0030425//dendrite;GO:0005783//endoplasmic reticulum;GO:0031362//anchored component of external side of plasma membrane;GO:0005925//focal adhesion;GO:0009897//external side of plasma membrane;GO:0016324//apical plasma membrane;GO:0043209//myelin sheath;GO:0030673//axolemma;GO:0030426//growth cone;GO:0009986//cell surface;GO:0045121//membrane raft;GO:0005887//integral component of plasma membrane;GO:0032590//dendrite membrane;GO:0005829//cytosol;GO:0005576//extracellular region;GO:0032809//neuronal cell body membrane;GO:0005886//plasma membrane","GO:0005178//integrin binding;GO:0019901//protein kinase binding;GO:0005096//GTPase activator activity;GO:0034235//GPI anchor binding","GO:0001952//regulation of cell-matrix adhesion;GO:0006501//C-terminal protein lipidation;GO:2000298//regulation of Rho-dependent protein serine/threonine kinase activity;GO:0043547//positive regulation of GTPase activity;GO:0050860//negative regulation of T cell receptor signaling pathway;GO:0098609//cell-cell adhesion;GO:0030334//regulation of cell migration;GO:0002693//positive regulation of cellular extravasation;GO:0007229//integrin-mediated signaling pathway;GO:0048041//focal adhesion assembly;GO:0034116//positive regulation of heterotypic cell-cell adhesion;GO:0043113//receptor clustering;GO:0070571//negative regulation of neuron projection regeneration;GO:0001525//angiogenesis;GO:0050852//T cell receptor signaling pathway;GO:0051894//positive regulation of focal adhesion assembly;GO:0007267//cell-cell signaling;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0030336//negative regulation of cell migration;GO:0050870//positive regulation of T cell activation;GO:0046777//protein autophosphorylation;GO:0061099//negative regulation of protein tyrosine kinase activity;GO:0007155//cell adhesion;GO:0006469//negative regulation of protein kinase activity;GO:0050771//negative regulation of axonogenesis;GO:0007010//cytoskeleton organization;GO:0046549//retinal cone cell development","K06514//Thy-1 cell surface antigen","NP_006279.2//thy-1 membrane glycoprotein preproprotein [Homo sapiens]","4;1//3"]
[883,2280,11.09,10.09,-0.136333191055353,0.406471607049986,"*",0.264204,"KYAT1","GO:0005654//nucleoplasm;GO:0005829//cytosol","GO:0047312//L-phenylalanine:pyruvate aminotransferase activity;GO:0047945//L-glutamine:pyruvate aminotransferase activity;GO:0070548//L-glutamine aminotransferase activity;GO:0008483//transaminase activity;GO:0016212//kynurenine-oxoglutarate transaminase activity;GO:0030170//pyridoxal phosphate binding;GO:0042803//protein homodimerization activity;GO:0047316//glutamine-phenylpyruvate transaminase activity;GO:0047804//cysteine-S-conjugate beta-lyase activity","GO:0008652//cellular amino acid biosynthetic process;GO:0009058//biosynthetic process;GO:0006575//cellular modified amino acid metabolic process;GO:0006569//tryptophan catabolic process;GO:0070189//kynurenine metabolic process;GO:0097053//L-kynurenine catabolic process;GO:0006559//L-phenylalanine catabolic process","K00816//kynurenine---oxoglutarate transaminase / cysteine-S-conjugate beta-lyase / glutamine---phenylpyruvate transaminase [EC:2.6.1.7 4.4.1.13 2.6.1.64]","XP_011786635.1//PREDICTED: kynurenine--oxoglutarate transaminase 1 isoform X1 [Colobus angolensis palliatus];XP_011786637.1//PREDICTED: kynurenine--oxoglutarate transaminase 1 isoform X3 [Colobus angolensis palliatus];NP_001339924.1//kynurenine--oxoglutarate transaminase 1 isoform d [Homo sapiens];NP_001339927.1//kynurenine--oxoglutarate transaminase 1 isoform e [Homo sapiens];NP_001274319.1//kynurenine--oxoglutarate transaminase 1 isoform c [Homo sapiens];XP_011786636.1//PREDICTED: kynurenine--oxoglutarate transaminase 1 isoform X2 [Colobus angolensis palliatus];XP_011894302.1//PREDICTED: kynurenine--oxoglutarate transaminase 1 isoform X1 [Cercocebus atys]","4;1//3;2//1"]
[3916,2560,64.56,58.75,-0.136051726938056,0.0107979651418312,"*",3.76516E-3,"LAMP1","GO:0016020//membrane;GO:0010008//endosome membrane;GO:0030425//dendrite;GO:0005770//late endosome;GO:0009897//external side of plasma membrane;GO:0044194//cytolytic granule;GO:0042470//melanosome;GO:0005737//cytoplasm;GO:0043025//neuronal cell body;GO:0035577//azurophil granule membrane;GO:0044754//autolysosome;GO:0005887//integral component of plasma membrane;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0070062//extracellular exosome;GO:0005765//lysosomal membrane;GO:0008021//synaptic vesicle;GO:0101003//ficolin-1-rich granule membrane;GO:0061474//phagolysosome membrane;GO:0005764//lysosome;GO:0048471//perinuclear region of cytoplasm;GO:0097208//alveolar lamellar body;GO:0042383//sarcolemma;GO:0005771//multivesicular body","GO:0019904//protein domain specific binding;GO:0001618//virus receptor activity;GO:0019899//enzyme binding","GO:0090160//Golgi to lysosome transport;GO:0072594//establishment of protein localization to organelle;GO:0008626//granzyme-mediated apoptotic signaling pathway;GO:0043323//positive regulation of natural killer cell degranulation;GO:0043312//neutrophil degranulation;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0048102//autophagic cell death;GO:0050821//protein stabilization;GO:1902513//regulation of organelle transport along microtubule","K06528//lysosomal-associated membrane protein 1/2","NP_005552.3//lysosome-associated membrane glycoprotein 1 precursor [Homo sapiens]","3//A2MP1"]
[9683,7121,5.91,5.38,-0.135551957620908,0.249662673574671,"*",0.1411796,"N4BP1","GO:0016605//PML body;GO:0005730//nucleolus","NA","GO:0031397//negative regulation of protein ubiquitination;GO:0034644//cellular response to UV;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process","K18668//ribonuclease ZC3H12 [EC:3.1.-.-]","NP_694574.3//NEDD4-binding protein 1 [Homo sapiens]","3//A2MP1"]
[6645,9771,4.7,4.28,-0.135049960163853,0.219732589983919,"*",0.1197566,"SNTB2","GO:0030658//transport vesicle membrane;GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005874//microtubule;GO:0005925//focal adhesion;GO:0005737//cytoplasm;GO:0043234//protein complex;GO:0016010//dystrophin-associated glycoprotein complex;GO:0045202//synapse","GO:0003779//actin binding;GO:0003723//RNA binding;GO:0005198//structural molecule activity;GO:0005516//calmodulin binding","NA","K01368//cathepsin S [EC:3.4.22.27];K14548//U3 small nucleolar RNA-associated protein 4;K12196//vacuolar protein-sorting-associated protein 4","XP_001147485.4//PREDICTED: beta-2-syntrophin [Pan troglodytes]","3//A2MP1"]
[79411,2403,5.39,4.91,-0.134562248437812,0.332713273124545,"*",0.200182,"GLB1L","GO:0005615//extracellular space;GO:0005773//vacuole","GO:0004565//beta-galactosidase activity","GO:0005975//carbohydrate metabolic process","K12309//beta-galactosidase [EC:3.2.1.23]","NP_078782.3//beta-galactosidase-1-like protein isoform 1 precursor [Homo sapiens];NP_001273356.1//beta-galactosidase-1-like protein isoform 2 precursor [Homo sapiens]","1//3;4"]
[9394,3966,11.72,10.68,-0.134060922734694,0.230275081573034,"*",0.128299,"HS6ST1","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0008146//sulfotransferase activity;GO:0017095//heparan sulfate 6-O-sulfotransferase activity","GO:0060716//labyrinthine layer blood vessel development;GO:0001525//angiogenesis;GO:0048286//lung alveolus development;GO:0006024//glycosaminoglycan biosynthetic process;GO:0048666//neuron development;GO:0015015//heparan sulfate proteoglycan biosynthetic process, enzymatic modification","K02514//heparan sulfate 6-O-sulfotransferase HS6ST1 [EC:2.8.2.-]","NP_004798.3//heparan-sulfate 6-O-sulfotransferase 1 [Homo sapiens]","2//1"]
[80724,4055,3.84,3.5,-0.133751388888827,0.490985420669578,"*",0.337856,"ACAD10","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors;GO:0016787//hydrolase activity;GO:0050660//flavin adenine dinucleotide binding;GO:0003995//acyl-CoA dehydrogenase activity","GO:0033539//fatty acid beta-oxidation using acyl-CoA dehydrogenase;GO:0006635//fatty acid beta-oxidation","K11729//acyl-CoA dehydrogenase family member 10","NP_079523.3//acyl-CoA dehydrogenase family member 10 isoform b [Homo sapiens];NP_001130010.1//acyl-CoA dehydrogenase family member 10 isoform a [Homo sapiens]","1//3;5"]
[140701,1776,3.63,3.31,-0.133138331188533,0.697259340144231,"*",0.581064,"ABHD16B","NA","GO:0016787//hydrolase activity","NA","K08869//aarF domain-containing kinase;K13172//serine/arginine repetitive matrix protein 2;K19720//collagen, type III, alpha","EAW75202.1//hCG1647005 [Homo sapiens]","3//A2MP1"]
[80110,4676,0.91,0.83,-0.132755208851772,0.73405269282854,"*",0.631164,"ZNF614","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","ELW48892.1//Zinc finger protein 614 [Tupaia chinensis]","3//A2MP1"]
[93,11373,0.57,0.52,-0.132450296023649,0.701142919194189,"*",0.5861,"ACVR2B","NA","NA","NA","K13596//activin receptor type-2B [EC:2.7.11.30]","XP_003894716.3//activin receptor type-2B isoform X1 [Papio anubis]","3//A2MP1"]
[1525,5079,3.78,3.45,-0.131789872555541,0.653599763097199,"*",0.496726,"CXADR","GO:0016323//basolateral plasma membrane;GO:0005615//extracellular space;GO:0031594//neuromuscular junction;GO:0030054//cell junction;GO:0005737//cytoplasm;GO:0030426//growth cone;GO:0005887//integral component of plasma membrane;GO:0005913//cell-cell adherens junction;GO:0005911//cell-cell junction;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005923//bicellular tight junction;GO:0014704//intercalated disc;GO:0005886//plasma membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016327//apicolateral plasma membrane;GO:0001669//acrosomal vesicle;GO:0005912//adherens junction;GO:0043005//neuron projection;GO:0030175//filopodium;GO:0044297//cell body;GO:0045121//membrane raft;GO:0043234//protein complex","GO:0050839//cell adhesion molecule binding;GO:0042802//identical protein binding;GO:0005102//receptor binding;GO:0086082//cell adhesive protein binding involved in AV node cell-bundle of His cell communication;GO:0071253//connexin binding;GO:0005178//integrin binding;GO:0030165//PDZ domain binding;GO:0001618//virus receptor activity;GO:0008013//beta-catenin binding","GO:0048739//cardiac muscle fiber development;GO:0098904//regulation of AV node cell action potential;GO:0008354//germ cell migration;GO:0045216//cell-cell junction organization;GO:0034109//homotypic cell-cell adhesion;GO:0050776//regulation of immune response;GO:0046629//gamma-delta T cell activation;GO:0031532//actin cytoskeleton reorganization;GO:0086072//AV node cell-bundle of His cell adhesion involved in cell communication;GO:0030593//neutrophil chemotaxis;GO:0007507//heart development;GO:0050900//leukocyte migration;GO:0051607//defense response to virus;GO:0070633//transepithelial transport;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007005//mitochondrion organization;GO:0086067//AV node cell to bundle of His cell communication;GO:0010669//epithelial structure maintenance","K06788//coxsackievirus and adenovirus receptor","NP_001193995.1//coxsackievirus and adenovirus receptor isoform 5 precursor [Homo sapiens];NP_001329.1//coxsackievirus and adenovirus receptor isoform 1 precursor [Homo sapiens];NP_001193993.1//coxsackievirus and adenovirus receptor isoform 3 precursor [Homo sapiens];NP_001193992.1//coxsackievirus and adenovirus receptor isoform 2 precursor [Homo sapiens];NP_001193994.1//coxsackievirus and adenovirus receptor isoform 4 precursor [Homo sapiens]","4;1//3"]
[114788,12643,0.23,0.21,-0.131244533278253,0.813164917520742,"*",0.730138,"CSMD3","NA","NA","NA","K17495//CUB and sushi domain-containing protein","XP_004011825.1//PREDICTED: CUB and sushi domain-containing protein 3 isoform X1 [Ovis aries];XP_004679689.1//PREDICTED: CUB and sushi domain-containing protein 3 [Condylura cristata];XP_003408490.1//PREDICTED: CUB and sushi domain-containing protein 3 isoform X2 [Loxodonta africana]","1//3;2//1"]
[27316,2090,113.34,103.53,-0.130608227952854,3.07493353665452E-3,"*",0.000950546,"RBMX","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005615//extracellular space;GO:0071013//catalytic step 2 spliceosome;GO:0030529//intracellular ribonucleoprotein complex;GO:0044530//supraspliceosomal complex;GO:0005719//nuclear euchromatin","GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0003682//chromatin binding;GO:0003727//single-stranded RNA binding;GO:0001047//core promoter binding","GO:0006397//mRNA processing;GO:0016070//RNA metabolic process;GO:0006509//membrane protein ectodomain proteolysis;GO:0001649//osteoblast differentiation;GO:0006376//mRNA splice site selection;GO:0000398//mRNA splicing, via spliceosome;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0051260//protein homooligomerization;GO:0006366//transcription from RNA polymerase II promoter;GO:0048026//positive regulation of mRNA splicing, via spliceosome;GO:0071347//cellular response to interleukin-1;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0008380//RNA splicing;GO:0048025//negative regulation of mRNA splicing, via spliceosome;GO:0051259//protein oligomerization","K12885//heterogeneous nuclear ribonucleoprotein G","KFO37284.1//Heterogeneous nuclear ribonucleoprotein G [Fukomys damarensis];NP_001158275.1//RNA-binding motif protein, X chromosome isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[8467,7926,18.48,16.89,-0.129795428614672,0.0226951417859488,"*",0.00865524,"SMARCA5","NA","NA","NA","K11654//SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:3.6.4.-]","XP_012309409.1//SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 isoform X1 [Aotus nancymaae]","3//A2MP1"]
[26022,1732,16.71,15.28,-0.129067190025439,0.382233514174096,"*",0.238878,"TMEM98","GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane","NA","NA","K21626//cyclin-D1-binding protein 1","NP_056359.2//transmembrane protein 98 [Homo sapiens]","1//3;2//1"]
[1616,2591,26.57,24.3,-0.128841913997363,0.063718333037122,"*",0.0278304,"DAXX","GO:0016605//PML body;GO:0070603//SWI/SNF superfamily-type complex;GO:0000775//chromosome, centromeric region","GO:0042393//histone binding;GO:0003714//transcription corepressor activity;GO:0047485//protein N-terminus binding;GO:0002039//p53 binding;GO:0031625//ubiquitin protein ligase binding;GO:0030295//protein kinase activator activity;GO:0046982//protein heterodimerization activity;GO:0019901//protein kinase binding;GO:0050681//androgen receptor binding;GO:0003713//transcription coactivator activity;GO:0032183//SUMO binding","GO:0031396//regulation of protein ubiquitination;GO:0045892//negative regulation of transcription, DNA-templated;GO:1903936//cellular response to sodium arsenite;GO:0006338//chromatin remodeling;GO:0006334//nucleosome assembly;GO:0034620//cellular response to unfolded protein;GO:1901216//positive regulation of neuron death;GO:0071280//cellular response to copper ion;GO:0034605//cellular response to heat;GO:0030521//androgen receptor signaling pathway;GO:0072738//cellular response to diamide;GO:0071276//cellular response to cadmium ion","K02308//death-associated protein 6","XP_007971134.1//PREDICTED: death domain-associated protein 6 isoform X3 [Chlorocebus sabaeus]","4;1//3"]
[9196,2458,1.53,1.4,-0.128104825747685,0.779056914759725,"*",0.682004,"KCNAB3","GO:0016021//integral component of membrane;GO:0005737//cytoplasm","GO:0005249//voltage-gated potassium channel activity","NA","K04884//potassium voltage-gated channel Shaker-related subfamily A, beta member 3","XP_004684688.1//PREDICTED: voltage-gated potassium channel subunit beta-3 isoform X1 [Condylura cristata]","3//A2MP1"]
[79913,2479,6.24,5.71,-0.128055283499406,0.573588799448656,"*",0.416816,"ACTR5","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031011//Ino80 complex;GO:0005737//cytoplasm","NA","GO:0006302//double-strand break repair;GO:0006355//regulation of transcription, DNA-templated;GO:0016579//protein deubiquitination;GO:0006351//transcription, DNA-templated;GO:0006310//DNA recombination;GO:0070914//UV-damage excision repair","K11672//actin-related protein 5","XP_003253623.2//PREDICTED: actin-related protein 5 [Nomascus leucogenys]","3//A2MP1"]
[51115,2219,9.95,9.11,-0.12724547162896,0.0833148623412479,"*",0.0377822,"RMDN1","GO:0000922//spindle pole;GO:0005874//microtubule;GO:0005813//centrosome;GO:0005739//mitochondrion","NA","NA","K15376//gephyrin [EC:2.10.1.1 2.7.7.75];K15696//RING finger protein 113B;K17985//activating molecule in BECN1-regulated autophagy protein 1;K01064//wingless-type MMTV integration site family, member 9","NP_001273648.1//regulator of microtubule dynamics protein 1 isoform 3 [Homo sapiens];NP_001273636.1//regulator of microtubule dynamics protein 1 isoform 2 [Homo sapiens];NP_057117.2//regulator of microtubule dynamics protein 1 isoform 1 [Homo sapiens];XP_016869008.1//PREDICTED: regulator of microtubule dynamics protein 1 isoform X12 [Homo sapiens]","1//3;2//1"]
[51704,2941,12.62,11.56,-0.12657051248187,0.335510433499584,"*",0.202138,"GPRC5B","GO:0016021//integral component of membrane","GO:0004930//G-protein coupled receptor activity","NA","K04619//G protein-coupled receptor family C group 5 member B","NP_001291700.1//G-protein coupled receptor family C group 5 member B isoform 2 [Homo sapiens];NP_001306363.1//G-protein coupled receptor family C group 5 member B [Macaca fascicularis]","1//3;2//1"]
[4668,3726,4.77,4.37,-0.126355986504913,0.527351415678231,"*",0.370176,"NAGA","GO:0070062//extracellular exosome;GO:0005764//lysosome;GO:0005737//cytoplasm","GO:0008456//alpha-N-acetylgalactosaminidase activity;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0042803//protein homodimerization activity;GO:0004557//alpha-galactosidase activity","GO:0046477//glycosylceramide catabolic process;GO:0016139//glycoside catabolic process;GO:0009311//oligosaccharide metabolic process;GO:0005975//carbohydrate metabolic process;GO:0019377//glycolipid catabolic process;GO:0016052//carbohydrate catabolic process","K01204//alpha-N-acetylgalactosaminidase [EC:3.2.1.49]","NP_000253.1//alpha-N-acetylgalactosaminidase precursor [Homo sapiens]","2//1"]
[129831,1831,3.12,2.86,-0.125530882083859,0.729304210962963,"*",0.616352,"RBM45","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0003723//RNA binding","GO:0007399//nervous system development;GO:0030154//cell differentiation","K13207//CUG-BP- and ETR3-like factor","NP_694453.2//RNA-binding protein 45 [Homo sapiens]","3//A2MP1"]
[5824,3667,17.92,16.43,-0.12523815710753,0.19029626572171,"*",0.1008544,"PEX19","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031526//brush border membrane;GO:0005777//peroxisome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043234//protein complex;GO:0016021//integral component of membrane;GO:0005778//peroxisomal membrane","GO:0047485//protein N-terminus binding;GO:0051117//ATPase binding;GO:0033328//peroxisome membrane targeting sequence binding;GO:0036105//peroxisome membrane class-1 targeting sequence binding","GO:0007031//peroxisome organization;GO:0055085//transmembrane transport;GO:0016557//peroxisome membrane biogenesis;GO:1900131//negative regulation of lipid binding;GO:0061077//chaperone-mediated protein folding;GO:0072663//establishment of protein localization to peroxisome;GO:0045046//protein import into peroxisome membrane;GO:0006625//protein targeting to peroxisome;GO:0072321//chaperone-mediated protein transport;GO:0050821//protein stabilization;GO:0016559//peroxisome fission","K13337//peroxin-19","XP_007974687.1//PREDICTED: peroxisomal biogenesis factor 19 isoform X1 [Chlorocebus sabaeus]","1//3;3//A2MP1"]
[26520,1101,29.23,26.8,-0.125216828460918,0.947344727583487,"*",0.902154,"TIMM9","GO:0005758//mitochondrial intermembrane space;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0042721//mitochondrial inner membrane protein insertion complex;GO:0042719//mitochondrial intermembrane space protein transporter complex","GO:0046872//metal ion binding;GO:0008565//protein transporter activity;GO:0008270//zinc ion binding;GO:0051087//chaperone binding;GO:0042803//protein homodimerization activity;GO:0005215//transporter activity","GO:0006626//protein targeting to mitochondrion;GO:0007605//sensory perception of sound;GO:0015031//protein transport;GO:0072321//chaperone-mediated protein transport;GO:0045039//protein import into mitochondrial inner membrane","K17777//mitochondrial import inner membrane translocase subunit TIM9","NP_001291417.1//mitochondrial import inner membrane translocase subunit Tim9 isoform b [Homo sapiens];NP_001291418.1//mitochondrial import inner membrane translocase subunit Tim9 isoform c [Homo sapiens];NP_001291419.1//mitochondrial import inner membrane translocase subunit Tim9 isoform d [Homo sapiens];EDL36554.1//translocase of inner mitochondrial membrane 9 homolog (yeast), isoform CRA_a, partial [Mus musculus]","1//3;3//A2MP1"]
[8824,3945,17.7,16.24,-0.124197727785184,0.175750103774946,"*",0.0915168,"CES2","GO:0005788//endoplasmic reticulum lumen;GO:0005783//endoplasmic reticulum","GO:0016787//hydrolase activity;GO:0047374//methylumbelliferyl-acetate deacetylase activity;GO:0052689//carboxylic ester hydrolase activity","GO:0006693//prostaglandin metabolic process;GO:0006805//xenobiotic metabolic process;GO:0009056//catabolic process","K03927//carboxylesterase 2 [EC:3.1.1.1 3.1.1.84 3.1.1.56]","NP_932327.1//cocaine esterase isoform 2 [Homo sapiens];NP_003860.2//cocaine esterase isoform 1 [Homo sapiens]","2//1;5"]
[84461,5217,12.55,11.52,-0.123546647395822,0.189629019768267,"*",0.1004058,"NEURL4","GO:0005814//centriole","NA","NA","K16777//neuralized-like protein 4","NP_001005408.1//neuralized-like protein 4 isoform 2 [Homo sapiens];NP_115818.2//neuralized-like protein 4 isoform 1 [Homo sapiens]","1//3;2//1"]
[84910,5224,3.78,3.47,-0.123450571642812,0.502145354733995,"*",0.348616,"TMEM87B","GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","NA","GO:0042147//retrograde transport, endosome to Golgi","NA","NP_116213.1//transmembrane protein 87B isoform 1 precursor [Homo sapiens];NP_001316843.1//transmembrane protein 87B isoform 2 precursor [Homo sapiens]","1//3;2//1"]
[1111,2885,14.39,13.22,-0.122344415232606,0.0290140093543759,"*",0.01139382,"CHEK1","GO:0043231//intracellular membrane-bounded organelle;GO:0005654//nucleoplasm;GO:0000785//chromatin;GO:0005657//replication fork","GO:0035402//histone kinase activity (H3-T11 specific);GO:0005524//ATP binding","GO:0006997//nucleus organization;GO:0006281//DNA repair;GO:0000077//DNA damage checkpoint;GO:0042127//regulation of cell proliferation;GO:0048096//chromatin-mediated maintenance of transcription;GO:1902742//apoptotic process involved in development;GO:0007093//mitotic cell cycle checkpoint;GO:0010767//regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage;GO:0001833//inner cell mass cell proliferation;GO:2000615//regulation of histone H3-K9 acetylation;GO:0000086//G2/M transition of mitotic cell cycle","K02216//serine/threonine-protein kinase Chk1 [EC:2.7.11.1]","XP_017747798.1//PREDICTED: serine/threonine-protein kinase Chk1 isoform X3 [Rhinopithecus bieti];XP_004052424.1//PREDICTED: serine/threonine-protein kinase Chk1 isoform X1 [Gorilla gorilla gorilla];NP_001317356.1//serine/threonine-protein kinase Chk1 isoform 3 [Homo sapiens]","1//3;2//1;5"]
[3326,2650,597.76,549.38,-0.121761969633629,{"v":2.08922450750695e-15,"d":"2.09E-15"},"*",{"v":1.411214e-16,"d":"1.41E-16"},"HSP90AB1","GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0031526//brush border membrane;GO:1990917//ooplasm;GO:0042470//melanosome;GO:0016234//inclusion body;GO:0005737//cytoplasm;GO:0008180//COP9 signalosome;GO:0005829//cytosol;GO:0005576//extracellular region;GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0070062//extracellular exosome;GO:0005765//lysosomal membrane;GO:0005634//nucleus;GO:0009986//cell surface;GO:1990913//sperm head plasma membrane;GO:0034751//aryl hydrocarbon receptor complex","GO:0030235//nitric-oxide synthase regulator activity;GO:0005524//ATP binding;GO:0031072//heat shock protein binding;GO:0070182//DNA polymerase binding;GO:0043008//ATP-dependent protein binding;GO:0003725//double-stranded RNA binding;GO:0019901//protein kinase binding;GO:0046983//protein dimerization activity;GO:0008144//drug binding;GO:0019887//protein kinase regulator activity;GO:0019900//kinase binding;GO:0032564//dATP binding;GO:0002134//UTP binding;GO:0017098//sulfonylurea receptor binding;GO:0042826//histone deacetylase binding;GO:0002135//CTP binding;GO:0042277//peptide binding;GO:0042803//protein homodimerization activity;GO:0045296//cadherin binding;GO:0023026//MHC class II protein complex binding;GO:0030911//TPR domain binding;GO:0044325//ion channel binding;GO:1990226//histone methyltransferase binding;GO:0051082//unfolded protein binding;GO:0005525//GTP binding;GO:0097718//disordered domain specific binding","GO:0035690//cellular response to drug;GO:0051973//positive regulation of telomerase activity;GO:0001890//placenta development;GO:0032092//positive regulation of protein binding;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0060334//regulation of interferon-gamma-mediated signaling pathway;GO:0019062//virion attachment to host cell;GO:0071157//negative regulation of cell cycle arrest;GO:0045597//positive regulation of cell differentiation;GO:1903660//negative regulation of complement-dependent cytotoxicity;GO:1901389//negative regulation of transforming growth factor beta activation;GO:1905323//telomerase holoenzyme complex assembly;GO:0006457//protein folding;GO:0031396//regulation of protein ubiquitination;GO:0043524//negative regulation of neuron apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0045793//positive regulation of cell size;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:2000010//positive regulation of protein localization to cell surface;GO:0006950//response to stress;GO:0071407//cellular response to organic cyclic compound;GO:0007004//telomere maintenance via telomerase;GO:0009651//response to salt stress;GO:0071353//cellular response to interleukin-4;GO:0033160//positive regulation of protein import into nucleus, translocation;GO:0032516//positive regulation of phosphoprotein phosphatase activity;GO:0051131//chaperone-mediated protein complex assembly;GO:0060338//regulation of type I interferon-mediated signaling pathway;GO:0097435//supramolecular fiber organization;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0042220//response to cocaine","K04079//molecular chaperone HtpG","NP_001258901.1//heat shock protein HSP 90-beta isoform c [Homo sapiens];NP_031381.2//heat shock protein HSP 90-beta isoform a [Homo sapiens];NP_001258900.1//heat shock protein HSP 90-beta isoform b [Homo sapiens]","1//3;3//A2MP1"]
[79085,3475,31.14,28.62,-0.121745272352369,0.0789589758754864,"*",0.0355696,"SLC25A23","NA","NA","NA","K14684//solute carrier family 25 (mitochondrial phosphate transporter), member 23/24/25/41","XP_022381519.1//calcium-binding mitochondrial carrier protein SCaMC-3 isoform X1 [Enhydra lutris kenyoni]","2//1"]
[57727,3154,20.14,18.52,-0.120979584746548,0.180507536097503,"*",0.0945704,"NCOA5","GO:0005634//nucleus;GO:0005615//extracellular space;GO:0015629//actin cytoskeleton","GO:0003723//RNA binding;GO:0003682//chromatin binding","GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0042593//glucose homeostasis","K10624//E3 ubiquitin-protein ligase RBBP6 [EC:2.3.2.27];K17585//phosphatase and actin regulator 4;K19756//radial spoke head protein 4A;K20102//YTH domain-containing family protein","NP_001335078.1//nuclear receptor coactivator 5 isoform 3 [Homo sapiens];NP_001335079.1//nuclear receptor coactivator 5 isoform 4 [Homo sapiens];AAG36793.1//nuclear receptor coactivator CIA, partial [Homo sapiens]","1//3;2//1"]
[64895,7386,3,2.76,-0.120294233717712,0.486042259536412,"*",0.33342,"PAPOLG","GO:0016020//membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0005829//cytosol","GO:0003723//RNA binding;GO:0004652//polynucleotide adenylyltransferase activity;GO:0046872//metal ion binding;GO:0005524//ATP binding","GO:0031123//RNA 3'-end processing;GO:0043631//RNA polyadenylation;GO:0006378//mRNA polyadenylation","K14376//poly(A) polymerase [EC:2.7.7.19]","NP_075045.2//poly(A) polymerase gamma [Homo sapiens]","3//A2MP1"]
[1659,4264,15.15,13.94,-0.12008723249189,0.169109015879932,"*",0.0874658,"DHX8","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0016604//nuclear body;GO:0005737//cytoplasm;GO:0071013//catalytic step 2 spliceosome","GO:0003723//RNA binding;GO:0004004//ATP-dependent RNA helicase activity;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0004386//helicase activity;GO:0003676//nucleic acid binding","GO:0006396//RNA processing;GO:0000398//mRNA splicing, via spliceosome;GO:0008380//RNA splicing","K12818//ATP-dependent RNA helicase DHX8/PRP22 [EC:3.6.4.13]","NP_001309150.1//ATP-dependent RNA helicase DHX8 isoform 8 [Homo sapiens];XP_016787218.1//PREDICTED: ATP-dependent RNA helicase DHX8 isoform X6 [Pan troglodytes];NP_001309147.1//ATP-dependent RNA helicase DHX8 isoform 5 [Homo sapiens];NP_001289552.1//ATP-dependent RNA helicase DHX8 isoform 2 [Homo sapiens];NP_004932.1//ATP-dependent RNA helicase DHX8 isoform 1 [Homo sapiens];NP_001309149.1//ATP-dependent RNA helicase DHX8 isoform 7 [Homo sapiens];NP_001309148.1//ATP-dependent RNA helicase DHX8 isoform 6 [Homo sapiens];XP_009249960.1//PREDICTED: ATP-dependent RNA helicase DHX8 isoform X1 [Pongo abelii]","1//3;2//1"]
[64431,2491,6.16,5.67,-0.119581615752673,0.602509080128748,"*",0.4453,"ACTR6","GO:0005634//nucleus","NA","GO:0006338//chromatin remodeling","K11662//actin-related protein 6","XP_005572035.1//PREDICTED: actin-related protein 6 isoform X1 [Macaca fascicularis]",4]
[56940,2087,7.31,6.73,-0.11926490134212,0.591600924412666,"*",0.43509,"DUSP22","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity","GO:0046330//positive regulation of JNK cascade;GO:0002710//negative regulation of T cell mediated immunity;GO:0042127//regulation of cell proliferation;GO:0000188//inactivation of MAPK activity;GO:0006915//apoptotic process;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0050860//negative regulation of T cell receptor signaling pathway;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0007275//multicellular organism development;GO:0006470//protein dephosphorylation;GO:0050868//negative regulation of T cell activation","K14165//atypical dual specificity phosphatase [EC:3.1.3.16 3.1.3.48]","NP_001273484.1//dual specificity protein phosphatase 22 isoform a [Homo sapiens];NP_064570.1//dual specificity protein phosphatase 22 isoform b [Homo sapiens]","4;1//3"]
[23256,2111,16.77,15.45,-0.118275850772609,0.118033073116037,"*",0.0566742,"SCFD1","GO:0032580//Golgi cisterna membrane;GO:0017119//Golgi transport complex;GO:0005829//cytosol;GO:0005798//Golgi-associated vesicle;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005801//cis-Golgi network","GO:0047485//protein N-terminus binding;GO:0019905//syntaxin binding","GO:0000902//cell morphogenesis;GO:1902902//negative regulation of autophagosome assembly;GO:0006904//vesicle docking involved in exocytosis;GO:0048208//COPII vesicle coating;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0009636//response to toxic substance;GO:0001666//response to hypoxia;GO:0060628//regulation of ER to Golgi vesicle-mediated transport;GO:0051223//regulation of protein transport;GO:1901998//toxin transport;GO:0006892//post-Golgi vesicle-mediated transport;GO:0015031//protein transport;GO:0006909//phagocytosis","K19998//sec1 family domain-containing protein 1","NP_001269961.1//sec1 family domain-containing protein 1 isoform e [Homo sapiens];XP_017751375.1//PREDICTED: sec1 family domain-containing protein 1 isoform X1 [Rhinopithecus bieti];XP_022277586.1//sec1 family domain-containing protein 1 isoform X3 [Canis lupus familiaris]","1//3;3//A2MP1;2//1"]
[51538,1514,14.93,13.76,-0.117733695432443,0.656121301177052,"*",0.499012,"ZCCHC17","GO:0005730//nucleolus;GO:0030529//intracellular ribonucleoprotein complex;GO:0022625//cytosolic large ribosomal subunit","GO:0003723//RNA binding;GO:0008270//zinc ion binding;GO:0003676//nucleic acid binding","NA","K10624//E3 ubiquitin-protein ligase RBBP6 [EC:2.3.2.27];K13171//serine/arginine repetitive matrix protein 1","XP_019692111.1//PREDICTED: nucleolar protein of 40 kDa isoform X1 [Felis catus];NP_001269502.1//nucleolar protein of 40 kDa isoform h [Homo sapiens];NP_001269496.1//nucleolar protein of 40 kDa isoform b [Homo sapiens];NP_001269500.1//nucleolar protein of 40 kDa isoform f [Homo sapiens];NP_001269495.1//nucleolar protein of 40 kDa isoform a [Homo sapiens];NP_001269501.1//nucleolar protein of 40 kDa isoform g [Homo sapiens];NP_001269498.1//nucleolar protein of 40 kDa isoform d [Homo sapiens]","1//3;3//A2MP1"]
[23603,3858,57,52.54,-0.117545718805835,0.0110644610059066,"*",0.00386986,"CORO1C","GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0016328//lateral plasma membrane;GO:0016600//flotillin complex;GO:0031982//vesicle;GO:0030027//lamellipodium;GO:0005737//cytoplasm","GO:0051015//actin filament binding;GO:0048365//Rac GTPase binding","GO:0010632//regulation of epithelial cell migration;GO:2000394//positive regulation of lamellipodium morphogenesis;GO:0010762//regulation of fibroblast migration;GO:0010633//negative regulation of epithelial cell migration;GO:0001932//regulation of protein phosphorylation;GO:0051893//regulation of focal adhesion assembly;GO:1900027//regulation of ruffle assembly;GO:0006909//phagocytosis;GO:0045184//establishment of protein localization;GO:0090630//activation of GTPase activity;GO:0007165//signal transduction;GO:0030036//actin cytoskeleton organization;GO:1900025//negative regulation of substrate adhesion-dependent cell spreading;GO:0001755//neural crest cell migration;GO:0051895//negative regulation of focal adhesion assembly;GO:1900024//regulation of substrate adhesion-dependent cell spreading;GO:0001933//negative regulation of protein phosphorylation;GO:0044387//negative regulation of protein kinase activity by regulation of protein phosphorylation","K13886//coronin-1B/1C/6","XP_008002778.1//PREDICTED: coronin-1C isoform X1 [Chlorocebus sabaeus];NP_001098707.1//coronin-1C isoform a [Homo sapiens]","1//3;3//A2MP1;2//1"]
[8908,3182,3.98,3.67,-0.116988367700436,0.533430445382586,"*",0.379686,"GYG2","GO:0005829//cytosol;GO:0043202//lysosomal lumen","GO:0102751//UDP-alpha-D-glucose:glucosyl-glycogenin alpha-D-glucosyltransferase activity;GO:0016757//transferase activity, transferring glycosyl groups;GO:0008466//glycogenin glucosyltransferase activity","GO:0005980//glycogen catabolic process;GO:0005978//glycogen biosynthetic process","K00750//glycogenin [EC:2.4.1.186]","NP_003909.2//glycogenin-2 isoform b [Homo sapiens];NP_001171631.1//glycogenin-2 isoform c [Homo sapiens];NP_001171632.1//glycogenin-2 isoform d [Homo sapiens];NP_001073324.1//glycogenin-2 isoform a [Homo sapiens]","1//3;2//1"]
[29889,2428,15.93,14.7,-0.115930111801583,0.285412021507234,"*",0.1654868,"GNL2","GO:0016020//membrane;GO:0005634//nucleus;GO:0005730//nucleolus","GO:0003723//RNA binding;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0042254//ribosome biogenesis","K14537//nuclear GTP-binding protein","NP_037417.1//nucleolar GTP-binding protein 2 isoform 1 [Homo sapiens];NP_001310553.1//nucleolar GTP-binding protein 2 isoform 3 [Homo sapiens];NP_001310552.1//nucleolar GTP-binding protein 2 isoform 2 [Homo sapiens]","1//3;2//1"]
[55211,2527,0.91,0.84,-0.115477217419936,0.862774371076462,"*",0.793262,"DPPA4","GO:0005654//nucleoplasm","NA","GO:0006355//regulation of transcription, DNA-templated;GO:0060484//lung-associated mesenchyme development;GO:0006351//transcription, DNA-templated;GO:0035019//somatic stem cell population maintenance","K09228//KRAB domain-containing zinc finger protein;K12022//tripartite motif-containing protein 46;K01368//cathepsin S [EC:3.4.22.27];K11447//histone demethylase [EC:1.14.11.-]","NP_001335858.1//developmental pluripotency-associated protein 4 isoform 3 [Homo sapiens];NP_060659.3//developmental pluripotency-associated protein 4 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[84126,2526,7.58,7,-0.114842926338763,0.378381019167085,"*",0.236044,"ATRIP","GO:0005654//nucleoplasm","GO:0070530//K63-linked polyubiquitin modification-dependent protein binding;GO:0004527//exonuclease activity","GO:1901796//regulation of signal transduction by p53 class mediator;GO:0006260//DNA replication;GO:0000077//DNA damage checkpoint;GO:0036297//interstrand cross-link repair","K10905//ATR interacting protein","NP_569055.1//ATR-interacting protein isoform 1 [Homo sapiens];NP_115542.2//ATR-interacting protein isoform 2 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[9949,5335,3.68,3.4,-0.114171019919311,0.477731866495507,"*",0.326164,"AMMECR1","GO:0005634//nucleus","NA","NA","K10385//loricrin;K02184//formin 2","XP_007990756.1//PREDICTED: AMME syndrome candidate gene 1 protein isoform X2 [Chlorocebus sabaeus];XP_007990755.1//PREDICTED: AMME syndrome candidate gene 1 protein isoform X1 [Chlorocebus sabaeus];NP_001128965.1//AMME syndrome candidate gene 1 protein homolog [Pongo abelii]","1//3;2//1"]
[140825,1440,0.79,0.73,-0.113956189297086,0.911133163718881,"*",0.854608,"NEURL2","GO:0005829//cytosol;GO:0005622//intracellular","NA","GO:0043687//post-translational protein modification;GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction","K16782//neuralized-like protein 2","NP_001265464.1//neuralized-like protein 2 isoform 2 [Homo sapiens];NP_542787.1//neuralized-like protein 2 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[9921,3864,40.93,37.84,-0.11324657810369,0.0438207739567048,"*",0.01824814,"RNF10","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0044212//transcription regulatory region DNA binding;GO:0004842//ubiquitin-protein transferase activity","GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0051865//protein autoubiquitination;GO:0006351//transcription, DNA-templated;GO:0031643//positive regulation of myelination;GO:0010626//negative regulation of Schwann cell proliferation;GO:0045893//positive regulation of transcription, DNA-templated","K15177//RNA polymerase-associated protein LEO1","NP_001317403.1//RING finger protein 10 isoform 2 [Homo sapiens];BAG63094.1//unnamed protein product [Homo sapiens]","1//3;4"]
[9341,2225,37.25,34.44,-0.113155282840042,0.170425336875151,"*",0.08836,"VAMP3","GO:0016324//apical plasma membrane;GO:0030054//cell junction;GO:0032588//trans-Golgi network membrane;GO:0055038//recycling endosome membrane;GO:0005829//cytosol;GO:0030665//clathrin-coated vesicle membrane;GO:0016021//integral component of membrane;GO:0045202//synapse;GO:0055037//recycling endosome;GO:0005886//plasma membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0030136//clathrin-coated vesicle;GO:0005622//intracellular;GO:0030670//phagocytic vesicle membrane;GO:0043005//neuron projection;GO:0048471//perinuclear region of cytoplasm;GO:0009986//cell surface;GO:0030141//secretory granule;GO:0030133//transport vesicle;GO:0031201//SNARE complex","GO:0017075//syntaxin-1 binding;GO:0000149//SNARE binding;GO:0005484//SNAP receptor activity","GO:0035493//SNARE complex assembly;GO:0034446//substrate adhesion-dependent cell spreading;GO:0001921//positive regulation of receptor recycling;GO:0006904//vesicle docking involved in exocytosis;GO:0042147//retrograde transport, endosome to Golgi;GO:0017156//calcium ion regulated exocytosis;GO:0016192//vesicle-mediated transport;GO:0061024//membrane organization;GO:1903531//negative regulation of secretion by cell;GO:0006906//vesicle fusion;GO:0061025//membrane fusion;GO:0043001//Golgi to plasma membrane protein transport;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0006461//protein complex assembly;GO:0006887//exocytosis","K13505//vesicle-associated membrane protein 3","XP_009233879.1//PREDICTED: vesicle-associated membrane protein 3 isoform X1 [Pongo abelii]","3//A2MP1"]
[50865,1221,29.4,27.19,-0.112740003698967,0.411444010335917,"*",0.269136,"HEBP1","GO:0070062//extracellular exosome","NA","NA","K01942//biotin---protein ligase [EC:6.3.4.9 6.3.4.10 6.3.4.11 6.3.4.15]","XP_003778029.2//PREDICTED: LOW QUALITY PROTEIN: heme-binding protein 1 [Pongo abelii]",4]
[51588,3225,11.24,10.4,-0.112058507192472,0.40565370338248,"*",0.26352,"PIAS4","GO:0016605//PML body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:1990234//transferase complex;GO:0016363//nuclear matrix;GO:0005737//cytoplasm","GO:0061665//SUMO ligase activity;GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0008022//protein C-terminus binding;GO:0008270//zinc ion binding;GO:0031625//ubiquitin protein ligase binding;GO:0019789//SUMO transferase activity","GO:0045892//negative regulation of transcription, DNA-templated;GO:0016925//protein sumoylation;GO:0010804//negative regulation of tumor necrosis factor-mediated signaling pathway;GO:1902231//positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage;GO:0006351//transcription, DNA-templated;GO:0033235//positive regulation of protein sumoylation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0016055//Wnt signaling pathway;GO:1902174//positive regulation of keratinocyte apoptotic process;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0032088//negative regulation of NF-kappaB transcription factor activity","K16065//E3 SUMO-protein ligase PIAS4","NP_056981.2//E3 SUMO-protein ligase PIAS4 [Homo sapiens]","3//A2MP1"]
[400709,3910,2.68,2.48,-0.111892880070897,0.661399579414239,"*",0.54145,"SIGLEC16","NA","NA","NA","K06750//sialic acid binding Ig-like lectin 11","XP_009434343.2//PREDICTED: sialic acid-binding Ig-like lectin 16 isoform X1 [Pan troglodytes]","1//3"]
[126308,3347,13.34,12.35,-0.111247624712545,0.363607304471256,"*",0.224506,"MOB3A","GO:0005622//intracellular","GO:0046872//metal ion binding;GO:0016301//kinase activity","NA","K06685//MOB kinase activator 1","NP_570719.1//MOB kinase activator 3A [Homo sapiens]","2//1"]
[57154,5700,11.36,10.52,-0.11082813021238,0.240031598035056,"*",0.1345914,"SMURF1","GO:0070062//extracellular exosome;GO:0030424//axon;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0043025//neuronal cell body","GO:0061630//ubiquitin protein ligase activity;GO:0048185//activin binding;GO:0070412//R-SMAD binding;GO:0070411//I-SMAD binding;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0005543//phospholipid binding","GO:0061734//parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization;GO:0030514//negative regulation of BMP signaling pathway;GO:0016567//protein ubiquitination;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0061736//engulfment of target by autophagosome;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0006511//ubiquitin-dependent protein catabolic process;GO:2000060//positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0006611//protein export from nucleus;GO:0071211//protein targeting to vacuole involved in autophagy;GO:0000209//protein polyubiquitination;GO:0061753//substrate localization to autophagosome;GO:0032801//receptor catabolic process;GO:0030154//cell differentiation;GO:0072659//protein localization to plasma membrane;GO:0030509//BMP signaling pathway;GO:0007398//ectoderm development;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0030579//ubiquitin-dependent SMAD protein catabolic process;GO:0030279//negative regulation of ossification;GO:1903861//positive regulation of dendrite extension;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0034394//protein localization to cell surface","K04678//E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]","NP_065162.1//E3 ubiquitin-protein ligase SMURF1 isoform 1 [Homo sapiens];NP_001186776.1//E3 ubiquitin-protein ligase SMURF1 isoform 3 [Homo sapiens];NP_851994.1//E3 ubiquitin-protein ligase SMURF1 isoform 2 [Homo sapiens]","1//3;2//1"]
[7335,2266,143.75,133.2,-0.109967873647838,0.00313271871356378,"*",0.000970174,"UBE2V1","GO:0035370//UBC13-UEV1A complex;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0031371//ubiquitin conjugating enzyme complex;GO:0000151//ubiquitin ligase complex;GO:0005829//cytosol;GO:0043234//protein complex","GO:0061630//ubiquitin protein ligase activity;GO:0031625//ubiquitin protein ligase binding","GO:0070534//protein K63-linked ubiquitination;GO:0070423//nucleotide-binding oligomerization domain containing signaling pathway;GO:0030154//cell differentiation;GO:0000187//activation of MAPK activity;GO:0050852//T cell receptor signaling pathway;GO:0006355//regulation of transcription, DNA-templated;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0007254//JNK cascade;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0006282//regulation of DNA repair;GO:0000209//protein polyubiquitination;GO:0006301//postreplication repair","K20656//transmembrane protein 189;K10704//ubiquitin-conjugating enzyme E2 variant","NP_071887.1//ubiquitin-conjugating enzyme E2 variant 1 isoform c [Homo sapiens];XP_015747055.1//PREDICTED: ubiquitin-conjugating enzyme E2 variant 1 isoform X1 [Python bivittatus];AAC02755.1//UEV1Bs, partial [Homo sapiens];XP_017827131.1//PREDICTED: ubiquitin-conjugating enzyme E2 variant 1 isoform X1 [Callithrix jacchus];XP_018872625.1//PREDICTED: ubiquitin-conjugating enzyme E2 variant 1 isoform X2 [Gorilla gorilla gorilla];XP_018872626.1//PREDICTED: ubiquitin-conjugating enzyme E2 variant 1 isoform X3 [Gorilla gorilla gorilla];XP_007423105.1//PREDICTED: ubiquitin-conjugating enzyme E2 variant 1 isoform X2 [Python bivittatus];XP_020839863.1//ubiquitin-conjugating enzyme E2 variant 1 isoform X2 [Phascolarctos cinereus];XP_014420422.1//PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein LOC102516405 [Camelus ferus];XP_008012503.1//PREDICTED: ubiquitin-conjugating enzyme E2 variant 1 isoform X1 [Chlorocebus sabaeus]","1//3;2//1;5"]
[54529,2487,14.15,13.12,-0.109034333101161,0.430514426893939,"*",0.284602,"ASNSD1","NA","GO:0042803//protein homodimerization activity;GO:0004066//asparagine synthase (glutamine-hydrolyzing) activity","GO:0006541//glutamine metabolic process;GO:0006529//asparagine biosynthetic process","K06825//fibrillin 1","NP_001340427.1//asparagine synthetase domain-containing protein 1 [Homo sapiens]","1//3;3//A2MP1"]
[252969,2238,9.5,8.81,-0.108785494297897,0.81736152657946,"*",0.73539,"NEIL2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005876//spindle microtubule","GO:0003906//DNA-(apurinic or apyrimidinic site) lyase activity;GO:0016799//hydrolase activity, hydrolyzing N-glycosyl compounds;GO:0008017//microtubule binding;GO:0003684//damaged DNA binding;GO:0140078//class I DNA-(apurinic or apyrimidinic site) lyase activity;GO:0019104//DNA N-glycosylase activity;GO:0008270//zinc ion binding;GO:0140080//class III/IV DNA-(apurinic or apyrimidinic site) lyase activity","GO:0006284//base-excision repair;GO:0045008//depyrimidination;GO:0006289//nucleotide-excision repair","K10568//endonuclease VIII-like 2 [EC:3.2.2.- 4.2.99.18]","NP_001129220.1//endonuclease 8-like 2 isoform c [Homo sapiens];XP_001142056.1//PREDICTED: endonuclease 8-like 2 isoform X1 [Pan troglodytes]","1//3;3//A2MP1;2//1"]
[10193,5205,10.94,10.15,-0.108133010720018,0.298570601326487,"*",0.1747238,"RNF41","GO:0071782//endoplasmic reticulum tubular network;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm","GO:0005135//interleukin-3 receptor binding;GO:0061630//ubiquitin protein ligase activity;GO:0005128//erythropoietin receptor binding;GO:0030971//receptor tyrosine kinase binding;GO:0004842//ubiquitin-protein transferase activity;GO:0031386//protein tag;GO:0046872//metal ion binding;GO:0019904//protein domain specific binding;GO:0016881//acid-amino acid ligase activity;GO:0008270//zinc ion binding;GO:0017160//Ral GTPase binding","GO:0097191//extrinsic apoptotic signaling pathway;GO:0016567//protein ubiquitination;GO:0051896//regulation of protein kinase B signaling;GO:0045637//regulation of myeloid cell differentiation;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0051865//protein autoubiquitination;GO:0006914//autophagy;GO:0010498//proteasomal protein catabolic process;GO:0045619//regulation of lymphocyte differentiation;GO:0000209//protein polyubiquitination;GO:0008285//negative regulation of cell proliferation;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0030336//negative regulation of cell migration;GO:0043408//regulation of MAPK cascade;GO:2000114//regulation of establishment of cell polarity;GO:0045732//positive regulation of protein catabolic process;GO:1901525//negative regulation of mitophagy;GO:2000377//regulation of reactive oxygen species metabolic process","K11981//E3 ubiquitin-protein ligase NRDP1 [EC:2.3.2.27]","XP_003906635.1//E3 ubiquitin-protein ligase NRDP1 isoform X2 [Papio anubis];NP_005776.1//E3 ubiquitin-protein ligase NRDP1 isoform 1 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[4720,2062,47.06,43.68,-0.107528464304445,0.16135977254902,"*",0.0829426,"NDUFS2","GO:0005759//mitochondrial matrix;GO:0005654//nucleoplasm;GO:0005747//mitochondrial respiratory chain complex I;GO:0005739//mitochondrion","GO:0009055//electron transfer activity;GO:0046872//metal ion binding;GO:0003954//NADH dehydrogenase activity;GO:0031625//ubiquitin protein ligase binding;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0048038//quinone binding;GO:0051287//NAD binding;GO:0008137//NADH dehydrogenase (ubiquinone) activity","GO:0006979//response to oxidative stress;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0042775//mitochondrial ATP synthesis coupled electron transport","K03935//NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:1.6.5.3 1.6.99.3]","ELV13286.1//NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial [Tupaia chinensis]","1//3;4"]
[8927,15964,0.14,0.13,-0.106915203916512,0.862833119161106,"*",0.793262,"BSN","GO:0030425//dendrite;GO:0030424//axon;GO:0048786//presynaptic active zone;GO:0005634//nucleus;GO:0060076//excitatory synapse;GO:0030054//cell junction;GO:0014069//postsynaptic density;GO:0048788//cytoskeleton of presynaptic active zone;GO:0009986//cell surface;GO:0044306//neuron projection terminus","GO:0046872//metal ion binding","GO:0007416//synapse assembly;GO:0035418//protein localization to synapse;GO:0099526//presynapse to nucleus signaling pathway;GO:0007268//chemical synaptic transmission","K16882//protein piccolo","NP_003449.2//protein bassoon [Homo sapiens]","3//A2MP1"]
[6185,2532,124.79,115.89,-0.106746245600669,0.00252001491172214,"*",0.000763072,"RPN2","GO:0016020//membrane;GO:0008250//oligosaccharyltransferase complex;GO:0005791//rough endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0000421//autophagosome membrane","GO:0043022//ribosome binding","GO:0042493//response to drug;GO:0018279//protein N-linked glycosylation via asparagine;GO:0006464//cellular protein modification process;GO:0006487//protein N-linked glycosylation;GO:0007568//aging","K12667//oligosaccharyltransferase complex subunit delta (ribophorin II)","NP_001311233.1//dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 isoform 7 precursor [Homo sapiens];EFB14847.1//hypothetical protein PANDA_003175, partial [Ailuropoda melanoleuca];NP_001311235.1//dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 isoform 9 [Homo sapiens];NP_001129243.1//dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 isoform 2 precursor [Homo sapiens];NP_001311234.1//dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 isoform 8 precursor [Homo sapiens];NP_001311232.1//dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 isoform 6 precursor [Homo sapiens];NP_001311228.1//dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 isoform 3 precursor [Homo sapiens];NP_001311231.1//dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 isoform 5 precursor [Homo sapiens];NP_001311230.1//dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 isoform 4 precursor [Homo sapiens]","4;1//3;2//1"]
[2145,4677,7.87,7.31,-0.106492229555049,0.425095685572897,"*",0.279636,"EZH1","GO:0005654//nucleoplasm;GO:0035098//ESC/E(Z) complex","GO:0003682//chromatin binding;GO:0018024//histone-lysine N-methyltransferase activity","GO:0070734//histone H3-K27 methylation;GO:0009653//anatomical structure morphogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0021766//hippocampus development;GO:0006351//transcription, DNA-templated","K17451//histone-lysine N-methyltransferase EZH1 [EC:2.1.1.43]","XP_005257202.1//PREDICTED: histone-lysine N-methyltransferase EZH1 isoform X2 [Homo sapiens];XP_011522819.1//PREDICTED: histone-lysine N-methyltransferase EZH1 isoform X1 [Homo sapiens];NP_001308008.1//histone-lysine N-methyltransferase EZH1 isoform 2 [Homo sapiens]","1//3;4"]
[1431,2997,129.59,120.43,-0.105759572037377,0.00188477615609756,"*",0.000556324,"CS","GO:0005759//mitochondrial matrix;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005739//mitochondrion","GO:0003723//RNA binding;GO:0004108//citrate (Si)-synthase activity","GO:0006099//tricarboxylic acid cycle;GO:0005975//carbohydrate metabolic process","K01647//citrate synthase [EC:2.3.3.1]","XP_011822625.1//PREDICTED: citrate synthase, mitochondrial isoform X1 [Mandrillus leucophaeus]","2//1"]
[55633,3545,4.7,4.37,-0.105027477064401,0.624910562244302,"*",0.468546,"TBC1D22B","GO:0012505//endomembrane system;GO:0005622//intracellular","GO:0071889//14-3-3 protein binding;GO:0017137//Rab GTPase binding;GO:0005096//GTPase activator activity","GO:0006886//intracellular protein transport;GO:0090630//activation of GTPase activity;GO:0031338//regulation of vesicle fusion","K20360//TBC1 domain family member 2","XP_003128420.3//TBC1 domain family member 22B [Sus scrofa]","3//A2MP1"]
[221710,4710,3.43,3.19,-0.104652152407943,0.650096069631219,"*",0.49329,"SMIM13","GO:0016021//integral component of membrane","NA","NA","K17399//DNA (cytosine-5)-methyltransferase 3B [EC:2.1.1.37];K20478//golgin subfamily B member 1","EAW55298.1//hCG2040263, isoform CRA_b [Homo sapiens]","1//3"]
[51090,1514,1.44,1.34,-0.10383581098454,0.859629259971364,"*",0.789294,"PLLP","GO:0070062//extracellular exosome;GO:0043218//compact myelin;GO:0045121//membrane raft;GO:0016021//integral component of membrane","GO:0019911//structural constituent of myelin sheath","GO:0009611//response to wounding;GO:0042552//myelination;GO:0001766//membrane raft polarization;GO:0008104//protein localization;GO:0006811//ion transport","NA","NP_057077.1//plasmolipin [Homo sapiens]","2//1"]
[27152,3275,0.29,0.27,-0.103093492964103,0.901666860856167,"*",0.842568,"INTU","GO:0036064//ciliary basal body;GO:0009986//cell surface;GO:0031514//motile cilium;GO:0005737//cytoplasm","NA","GO:0007399//nervous system development;GO:0010839//negative regulation of keratinocyte proliferation;GO:0051782//negative regulation of cell division;GO:0008589//regulation of smoothened signaling pathway;GO:0030216//keratinocyte differentiation;GO:1905515//non-motile cilium assembly;GO:0044458//motile cilium assembly;GO:0030278//regulation of ossification;GO:0042733//embryonic digit morphogenesis;GO:0060271//cilium assembly;GO:0021513//spinal cord dorsal/ventral patterning;GO:0031069//hair follicle morphogenesis;GO:0060173//limb development;GO:0045880//positive regulation of smoothened signaling pathway;GO:0021915//neural tube development","K07820//beta-1,3-galactosyltransferase 2 [EC:2.4.1.86]","NP_056508.2//protein inturned [Homo sapiens]","3//A2MP1"]
[57701,4918,6.82,6.35,-0.103015147364644,0.475831131583777,"*",0.324628,"NCKAP5L","GO:0035371//microtubule plus-end;GO:0005813//centrosome;GO:0005737//cytoplasm","NA","GO:0007019//microtubule depolymerization;GO:0001578//microtubule bundle formation","K06237//collagen, type IV, alpha;K18401//KAT8 regulatory NSL complex subunit 2;K06236//collagen, type I, alpha;K19720//collagen, type III, alpha","NP_001032895.2//nck-associated protein 5-like [Homo sapiens]","3//A2MP1"]
[6451,2090,16.88,15.73,-0.101796233291498,0.46736656423499,"*",0.317244,"SH3BGRL","GO:0070062//extracellular exosome;GO:0005737//cytoplasm","NA","NA","K13912//deleted in malignant brain tumors 1 protein","XP_004407393.1//PREDICTED: SH3 domain-binding glutamic acid-rich-like protein [Odobenus rosmarus divergens]","2//1"]
[286128,4620,9.66,9.01,-0.100496083022235,0.661576907408823,"*",0.541678,"ZFP41","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_021570783.1//LOW QUALITY PROTEIN: uncharacterized protein LOC103266035, partial [Carlito syrichta]","2//1;5"]
[55341,3589,12.35,11.52,-0.100370325029728,0.402036248816768,"*",0.260566,"LSG1","GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0015030//Cajal body","GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0051168//nuclear export","K14539//large subunit GTPase 1 [EC:3.6.1.-]","XP_003895355.1//large subunit GTPase 1 homolog [Papio anubis]","2//1"]
[203100,2130,1.94,1.81,-0.100066955103922,0.84695122506183,"*",0.771768,"HTRA4","GO:0005576//extracellular region","GO:0004252//serine-type endopeptidase activity;GO:0005520//insulin-like growth factor binding;GO:0004175//endopeptidase activity","GO:0001558//regulation of cell growth;GO:0006508//proteolysis;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway","K08786//HtrA serine peptidase 4 [EC:3.4.21.-]","NP_710159.1//serine protease HTRA4 precursor [Homo sapiens]","3//A2MP1"]
[6949,4911,44.74,41.76,-0.0994435444892345,0.0166126326639344,"*",0.00609012,"TCOF1","GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0001650//fibrillar center","GO:0003723//RNA binding;GO:0001042//RNA polymerase I core binding;GO:0046982//protein heterodimerization activity;GO:0005215//transporter activity","GO:0014032//neural crest cell development;GO:0014029//neural crest formation;GO:0001501//skeletal system development;GO:0006417//regulation of translation","K14562//Treacher Collins syndrome protein","NP_001128717.1//treacle protein isoform f [Homo sapiens];NP_001128716.1//treacle protein isoform e [Homo sapiens];NP_000347.2//treacle protein isoform b [Homo sapiens];NP_001008657.1//treacle protein isoform c [Homo sapiens];NP_001128715.1//treacle protein isoform d [Homo sapiens];NP_001182070.1//treacle protein isoform g [Homo sapiens]","1//3;3//A2MP1;2//1"]
[22800,2350,12.78,11.93,-0.0992937932517663,0.525475457742079,"*",0.368596,"RRAS2","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005783//endoplasmic reticulum;GO:0005925//focal adhesion;GO:0005622//intracellular;GO:0005886//plasma membrane","GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0001649//osteoblast differentiation;GO:0007165//signal transduction;GO:0030335//positive regulation of cell migration;GO:0009987//cellular process;GO:1901214//regulation of neuron death;GO:0007265//Ras protein signal transduction","K07830//Ras-related protein R-Ras2","XP_004752081.2//PREDICTED: ras-related protein R-Ras2 isoform X1 [Mustela putorius furo];XP_009244868.1//PREDICTED: ras-related protein R-Ras2 [Pongo abelii];XP_003781167.1//PREDICTED: ras-related protein R-Ras2 isoform X1 [Otolemur garnettii];NP_036382.2//ras-related protein R-Ras2 isoform a [Homo sapiens]","1//3;2//1;5"]
[4784,5579,4.72,4.41,-0.0980082038043206,0.555279395150778,"*",0.4,"NFIX","GO:0005634//nucleus","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0003705//transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding","GO:0021549//cerebellum development;GO:0021680//cerebellar Purkinje cell layer development;GO:0006260//DNA replication;GO:0006351//transcription, DNA-templated;GO:0021707//cerebellar granule cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0048708//astrocyte differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter","K09171//nuclear factor I/X","XP_019519733.1//PREDICTED: nuclear factor 1 X-type isoform X1 [Hipposideros armiger];XP_004635598.1//PREDICTED: nuclear factor 1 X-type isoform X1 [Octodon degus]","3//A2MP1;2//1"]
[4355,4275,3.69,3.45,-0.0970244543948645,0.641308356652526,"*",0.520506,"MPP2","GO:0016020//membrane;GO:0005856//cytoskeleton;GO:0014069//postsynaptic density;GO:0005737//cytoplasm;GO:0043198//dendritic shaft;GO:0032590//dendrite membrane;GO:0005887//integral component of plasma membrane;GO:0043197//dendritic spine;GO:0032591//dendritic spine membrane","GO:0044325//ion channel binding;GO:0030165//PDZ domain binding;GO:0004385//guanylate kinase activity","GO:0007165//signal transduction;GO:0060291//long-term synaptic potentiation;GO:0051260//protein homooligomerization;GO:0060079//excitatory postsynaptic potential","K06103//calcium/calmodulin-dependent serine protein kinase [EC:2.7.11.1]","XP_012299369.1//MAGUK p55 subfamily member 2 isoform X4 [Aotus nancymaae];XP_011523129.2//PREDICTED: MAGUK p55 subfamily member 2 isoform X1 [Homo sapiens];XP_010361386.1//PREDICTED: MAGUK p55 subfamily member 2 isoform X1 [Rhinopithecus roxellana];NP_001265305.2//MAGUK p55 subfamily member 2 isoform 8 [Homo sapiens];NP_001265299.1//MAGUK p55 subfamily member 2 isoform 1 [Homo sapiens];XP_008010683.1//PREDICTED: MAGUK p55 subfamily member 2 isoform X1 [Chlorocebus sabaeus]","4;1//3;2//1"]
[132299,794,47.88,44.77,-0.0968908340399577,0.650657226327945,"*",0.493838,"OCIAD2","GO:0005768//endosome;GO:0005743//mitochondrial inner membrane","NA","NA","NA","NP_689611.1//OCIA domain-containing protein 2 isoform 2 [Homo sapiens];NP_001014446.1//OCIA domain-containing protein 2 isoform 1 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[11078,3951,17.23,16.12,-0.0960709576969808,0.696924583884546,"*",0.580436,"TRIOBP","GO:0005634//nucleus;GO:0005815//microtubule organizing center;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0005737//cytoplasm;GO:0030496//midbody","GO:0051015//actin filament binding;GO:0045159//myosin II binding;GO:0031625//ubiquitin protein ligase binding;GO:0017049//GTP-Rho binding","GO:0051301//cell division;GO:0051016//barbed-end actin filament capping;GO:0007049//cell cycle;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:0030047//actin modification","K10955//mucin-2;K16628//collagen, type VII, alpha;K03129//transcription initiation factor TFIID subunit 4;K22020//mucin-19;K20478//golgin subfamily B member 1","NP_001034230.1//TRIO and F-actin-binding protein isoform 6 [Homo sapiens];XP_016794638.1//PREDICTED: TRIO and F-actin-binding protein isoform X6 [Pan troglodytes];NP_619538.2//TRIO and F-actin-binding protein isoform 2 [Homo sapiens]","2//1;5"]
[114659,3191,3.9,3.65,-0.0955776599822311,0.613800615255658,"*",0.45841,"LRRC37B","GO:0016021//integral component of membrane","NA","NA","K20636//Rho GTPase-activating protein 12/27;K06839//slit 2;K10874//RAD52 motif-containing protein 1","BAG63955.1//unnamed protein product [Homo sapiens]","1//3;2//1"]
[25960,6050,1.25,1.17,-0.0954195650786826,0.768760500645902,"*",0.670584,"ADGRA2","GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0030175//filopodium","GO:0004930//G-protein coupled receptor activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0045765//regulation of angiogenesis;GO:1900747//negative regulation of vascular endothelial growth factor signaling pathway;GO:0043542//endothelial cell migration;GO:0090210//regulation of establishment of blood-brain barrier;GO:0050920//regulation of chemotaxis;GO:0010595//positive regulation of endothelial cell migration;GO:0007166//cell surface receptor signaling pathway;GO:0007417//central nervous system development;GO:0002040//sprouting angiogenesis","K08461//G protein-coupled receptor 124","NP_116166.9//adhesion G protein-coupled receptor A2 precursor [Homo sapiens]","9//1"]
[2204,2302,6.2,5.81,-0.0937300518697086,0.684435335602451,"*",0.566478,"FCAR","GO:0005887//integral component of plasma membrane;GO:0101003//ficolin-1-rich granule membrane;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane;GO:0005576//extracellular region;GO:0070821//tertiary granule membrane;GO:0005886//plasma membrane","GO:0019766//IgA receptor activity;GO:0019862//IgA binding","GO:0042119//neutrophil activation;GO:0071222//cellular response to lipopolysaccharide;GO:0071356//cellular response to tumor necrosis factor;GO:0033031//positive regulation of neutrophil apoptotic process;GO:0002446//neutrophil mediated immunity;GO:0071346//cellular response to interferon-gamma;GO:0071354//cellular response to interleukin-6;GO:0043312//neutrophil degranulation;GO:0038093//Fc receptor signaling pathway;GO:0006955//immune response;GO:1903209//positive regulation of oxidative stress-induced cell death;GO:0035457//cellular response to interferon-alpha;GO:0097011//cellular response to granulocyte macrophage colony-stimulating factor stimulus","K06513//CD89 antigen","NP_579807.1//immunoglobulin alpha Fc receptor isoform e [Homo sapiens];NP_579808.1//immunoglobulin alpha Fc receptor isoform f [Homo sapiens];NP_579806.1//immunoglobulin alpha Fc receptor isoform d [Homo sapiens];NP_579812.1//immunoglobulin alpha Fc receptor isoform h [Homo sapiens];NP_579803.1//immunoglobulin alpha Fc receptor isoform b precursor [Homo sapiens];NP_001991.1//immunoglobulin alpha Fc receptor isoform a precursor [Homo sapiens];NP_579805.1//immunoglobulin alpha Fc receptor isoform c precursor [Homo sapiens];NP_579811.1//immunoglobulin alpha Fc receptor isoform g [Homo sapiens]","3//A2MP1"]
[84294,3693,7.01,6.57,-0.0935210736882935,0.574186337926283,"*",0.417394,"UTP23","GO:0032040//small-subunit processome;GO:0005730//nucleolus","GO:0003723//RNA binding;GO:0070181//small ribosomal subunit rRNA binding;GO:0048027//mRNA 5'-UTR binding;GO:0003730//mRNA 3'-UTR binding","GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000480//endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)","K14773//U3 small nucleolar RNA-associated protein 23","NP_115710.2//rRNA-processing protein UTP23 homolog [Homo sapiens]","2//1"]
[6490,1973,0.32,0.3,-0.0931094043914815,0.873721910496339,"*",0.806664,"PMEL","GO:0032585//multivesicular body membrane;GO:0042470//melanosome;GO:0005887//integral component of plasma membrane;GO:0005794//Golgi apparatus;GO:0005576//extracellular region;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane","GO:0042802//identical protein binding","GO:0042438//melanin biosynthetic process;GO:0048066//developmental pigmentation;GO:0032438//melanosome organization","K17304//melanocyte protein PMEL","NP_008859.1//melanocyte protein PMEL isoform 3 preproprotein [Homo sapiens];NP_001307051.1//melanocyte protein PMEL isoform 5 preproprotein [Homo sapiens];NP_001186982.1//melanocyte protein PMEL isoform 2 precursor [Homo sapiens];NP_001307050.1//melanocyte protein PMEL isoform 4 preproprotein [Homo sapiens];NP_001186983.1//melanocyte protein PMEL isoform 1 preproprotein [Homo sapiens]","1//3;4"]
[54797,1833,15.26,14.31,-0.0927312901078626,0.637381012687619,"*",0.481168,"MED18","NA","NA","NA","K15135//mediator of RNA polymerase II transcription subunit 18","XP_009201399.1//mediator of RNA polymerase II transcription subunit 18 isoform X1 [Papio anubis];XP_011761389.1//PREDICTED: mediator of RNA polymerase II transcription subunit 18 isoform X2 [Macaca nemestrina]","1//3;2//1"]
[374354,6409,3.56,3.34,-0.0920291384923456,0.617044924442955,"*",0.461142,"NHLRC2","GO:0031093//platelet alpha granule lumen;GO:0005623//cell;GO:0005576//extracellular region","NA","GO:0002576//platelet degranulation;GO:0045454//cell redox homeostasis","K12581//CCR4-NOT transcription complex subunit 7/8;K11447//histone demethylase [EC:1.14.11.-]","XP_002756652.2//PREDICTED: NHL repeat-containing protein 2 isoform X1 [Callithrix jacchus]","3//A2MP1"]
[3234,2596,2.43,2.28,-0.0919224894410391,0.787026213916614,"*",0.696026,"HOXD8","GO:0005634//nucleus","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0009952//anterior/posterior pattern specification;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007275//multicellular organism development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0008595//anterior/posterior axis specification, embryo;GO:0048705//skeletal system morphogenesis","K09308//homeobox protein HoxB/C/D8","NP_062458.1//homeobox protein Hox-D8 isoform 1 [Homo sapiens];NP_001186675.1//homeobox protein Hox-D8 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[51283,3035,29.67,27.85,-0.091327599252873,0.218867339857242,"*",0.119011,"BFAR","GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0005887//integral component of plasma membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0089720//caspase binding;GO:0061630//ubiquitin protein ligase activity;GO:0046872//metal ion binding;GO:0030674//protein binding, bridging","GO:0070534//protein K63-linked ubiquitination;GO:0070936//protein K48-linked ubiquitination;GO:0043066//negative regulation of apoptotic process;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0006915//apoptotic process;GO:1903895//negative regulation of IRE1-mediated unfolded protein response;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0051865//protein autoubiquitination;GO:0000209//protein polyubiquitination","K15684//bifunctional apoptosis regulator","NP_057645.1//bifunctional apoptosis regulator isoform 1 [Homo sapiens];NP_001317429.1//bifunctional apoptosis regulator isoform 2 [Homo sapiens]","1//3;2//1"]
[8932,5175,13.63,12.8,-0.0906417519178472,0.308775103947508,"*",0.1826478,"MBD2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0043234//protein complex;GO:0005829//cytosol;GO:0000118//histone deacetylase complex;GO:0000792//heterochromatin;GO:0000790//nuclear chromatin","GO:0035197//siRNA binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003729//mRNA binding;GO:0003696//satellite DNA binding;GO:0008327//methyl-CpG binding;GO:0070742//C2H2 zinc finger domain binding;GO:0019904//protein domain specific binding;GO:0003682//chromatin binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0031492//nucleosomal DNA binding","GO:0042127//regulation of cell proliferation;GO:0035563//positive regulation of chromatin binding;GO:0048568//embryonic organ development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0032355//response to estradiol;GO:0071407//cellular response to organic cyclic compound;GO:0043044//ATP-dependent chromatin remodeling;GO:0000183//chromatin silencing at rDNA;GO:0044030//regulation of DNA methylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0009612//response to mechanical stimulus;GO:0007507//heart development;GO:0006351//transcription, DNA-templated;GO:0007568//aging;GO:0030177//positive regulation of Wnt signaling pathway;GO:0006346//methylation-dependent chromatin silencing;GO:0031667//response to nutrient levels;GO:0042711//maternal behavior;GO:0043623//cellular protein complex assembly","K11590//methyl-CpG-binding domain protein 2","NP_056647.1//methyl-CpG-binding domain protein 2 testis-specific isoform [Homo sapiens];NP_003918.1//methyl-CpG-binding domain protein 2 isoform 1 [Homo sapiens]",4]
[128239,6069,12.42,11.67,-0.0898606125131334,0.320785304956513,"*",0.1916398,"IQGAP3","GO:0005829//cytosol;GO:0005911//cell-cell junction;GO:0016328//lateral plasma membrane","GO:0017048//Rho GTPase binding;GO:0070856//myosin VI light chain binding;GO:0005516//calmodulin binding","GO:0000187//activation of MAPK activity;GO:0008361//regulation of cell size;GO:0010629//negative regulation of gene expression;GO:0010628//positive regulation of gene expression;GO:0070371//ERK1 and ERK2 cascade;GO:0071310//cellular response to organic substance;GO:0043087//regulation of GTPase activity;GO:0033601//positive regulation of mammary gland epithelial cell proliferation;GO:0000082//G1/S transition of mitotic cell cycle;GO:0007265//Ras protein signal transduction","K05767//Ras GTPase-activating-like protein IQGAP2/3","NP_839943.2//ras GTPase-activating-like protein IQGAP3 [Homo sapiens]",4]
[91833,2381,11.84,11.13,-0.0892154882869902,0.0238833717819843,"*",0.00916222,"WDR20","GO:0005654//nucleoplasm","GO:0036459//thiol-dependent ubiquitinyl hydrolase activity","GO:0016579//protein deubiquitination","K06100//symplekin;K04799//flap endonuclease-1 [EC:3.-.-.-]","AAH28387.1//WD repeat domain 20 [Homo sapiens];NP_851808.1//WD repeat-containing protein 20 isoform 1 [Homo sapiens];NP_001340587.1//WD repeat-containing protein 20 isoform 14 [Homo sapiens];NP_001229343.1//WD repeat-containing protein 20 isoform 4 [Homo sapiens];NP_851825.1//WD repeat-containing protein 20 isoform 3 [Homo sapiens];NP_001317157.1//WD repeat-containing protein 20 isoform 11 [Homo sapiens];NP_001340589.1//WD repeat-containing protein 20 isoform 16 [Homo sapiens];XP_014203186.1//PREDICTED: WD repeat-containing protein 20 isoform X5 [Pan paniscus];XP_018865436.1//PREDICTED: WD repeat-containing protein 20 isoform X2 [Gorilla gorilla gorilla];NP_653175.2//WD repeat-containing protein 20 isoform 2 [Homo sapiens];XP_007986076.1//PREDICTED: WD repeat-containing protein 20 isoform X3 [Chlorocebus sabaeus];NP_001307059.1//WD repeat-containing protein 20 isoform 10 [Homo sapiens];NP_001340586.1//WD repeat-containing protein 20 isoform 13 [Homo sapiens];NP_001229344.1//WD repeat-containing protein 20 isoform 5 [Homo sapiens];NP_001340608.1//WD repeat-containing protein 20 isoform 23 [Homo sapiens];NP_001340588.1//WD repeat-containing protein 20 isoform 15 [Homo sapiens];BAG52255.1//unnamed protein product [Homo sapiens];NP_001229345.1//WD repeat-containing protein 20 isoform 6 [Homo sapiens];NP_001229347.1//WD repeat-containing protein 20 isoform 8 [Homo sapiens];NP_001340590.1//WD repeat-containing protein 20 isoform 17 [Homo sapiens];XP_011535639.1//PREDICTED: WD repeat-containing protein 20 isoform X3 [Homo sapiens];NP_001229346.1//WD repeat-containing protein 20 isoform 7 [Homo sapiens];NP_001340585.1//WD repeat-containing protein 20 isoform 12 [Homo sapiens];NP_001340609.1//WD repeat-containing protein 20 isoform 24 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[158586,5651,3.18,2.99,-0.0888812810862503,0.639399334363412,"*",0.518116,"ZXDB","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K20828//zinc finger protein 143/76;K10485//BTB/POZ domain-containing protein 13 (germ cell-less protein-like 1)","XP_011829054.1//PREDICTED: zinc finger X-linked protein ZXDB [Mandrillus leucophaeus]","3//A2MP1"]
[223,2500,18.31,17.22,-0.0885466484004931,0.474904130039489,"*",0.323728,"ALDH9A1","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0004028//3-chloroallyl aldehyde dehydrogenase activity;GO:0033737//1-pyrroline dehydrogenase activity;GO:0047105//4-trimethylammoniobutyraldehyde dehydrogenase activity;GO:0016491//oxidoreductase activity;GO:0019145//aminobutyraldehyde dehydrogenase activity;GO:0004029//aldehyde dehydrogenase (NAD) activity","GO:0042136//neurotransmitter biosynthetic process;GO:0006081//cellular aldehyde metabolic process;GO:0042445//hormone metabolic process;GO:0045329//carnitine biosynthetic process;GO:0055114//oxidation-reduction process","K00149//aldehyde dehydrogenase family 9 member A1 [EC:1.2.1.47 1.2.1.3]","NP_000687.3//4-trimethylaminobutyraldehyde dehydrogenase [Homo sapiens]","3//A2MP1"]
[7360,2153,35.89,33.77,-0.0878397438086007,0.34564743552713,"*",0.20976,"UGP2","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0032557//pyrimidine ribonucleotide binding;GO:0042802//identical protein binding;GO:0003983//UTP:glucose-1-phosphate uridylyltransferase activity;GO:0005536//glucose binding","GO:0005977//glycogen metabolic process;GO:0005978//glycogen biosynthetic process;GO:0006011//UDP-glucose metabolic process;GO:0006065//UDP-glucuronate biosynthetic process;GO:0019255//glucose 1-phosphate metabolic process","K00963//UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]","NP_006750.3//UTP--glucose-1-phosphate uridylyltransferase isoform a [Homo sapiens];XP_012877992.1//PREDICTED: UTP--glucose-1-phosphate uridylyltransferase isoform X1 [Dipodomys ordii]","1//3;3//A2MP1"]
[54596,4005,0.51,0.48,-0.0874628412503394,0.940935285629493,"*",0.893164,"L1TD1","GO:0030529//intracellular ribonucleoprotein complex","GO:0003727//single-stranded RNA binding","GO:0032197//transposition, RNA-mediated","K19475//WAS/WASL-interacting protein;K19607//X-linked retinitis pigmentosa GTPase regulator;K18626//trichohyalin","NP_061952.3//LINE-1 type transposase domain-containing protein 1 [Homo sapiens]","4;1//3"]
[4678,2562,31.83,29.96,-0.0873495331771698,0.0174310281702561,"*",0.00643488,"NASP","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0043234//protein complex;GO:0000790//nuclear chromatin;GO:0005737//cytoplasm","GO:0042393//histone binding;GO:0051879//Hsp90 protein binding;GO:0032403//protein complex binding","GO:0006260//DNA replication;GO:0006334//nucleosome assembly;GO:0043486//histone exchange;GO:0008584//male gonad development;GO:0006335//DNA replication-dependent nucleosome assembly;GO:0001824//blastocyst development;GO:0033574//response to testosterone;GO:0008283//cell proliferation;GO:0006336//DNA replication-independent nucleosome assembly;GO:0015031//protein transport;GO:0007049//cell cycle","K11291//nuclear autoantigenic sperm protein","NP_001182122.1//nuclear autoantigenic sperm protein isoform 4 [Homo sapiens];NP_689511.2//nuclear autoantigenic sperm protein isoform 3 [Homo sapiens];NP_002473.2//nuclear autoantigenic sperm protein isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[122622,1796,3.08,2.9,-0.086877450679967,0.818887972743707,"*",0.737276,"ADSSL1","GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0000287//magnesium ion binding;GO:0051015//actin filament binding;GO:0042803//protein homodimerization activity;GO:0003924//GTPase activity;GO:0046872//metal ion binding;GO:0042301//phosphate ion binding;GO:0005525//GTP binding;GO:0004019//adenylosuccinate synthase activity","GO:0071257//cellular response to electrical stimulus;GO:0035690//cellular response to drug;GO:0006531//aspartate metabolic process;GO:0044208//'de novo' AMP biosynthetic process;GO:0006167//AMP biosynthetic process;GO:0006541//glutamine metabolic process;GO:0014850//response to muscle activity;GO:0042594//response to starvation;GO:0002376//immune system process;GO:0046040//IMP metabolic process;GO:0009168//purine ribonucleoside monophosphate biosynthetic process","K01939//adenylosuccinate synthase [EC:6.3.4.4]","CAD62614.1//unnamed protein product, partial [Homo sapiens];XP_007986184.1//PREDICTED: adenylosuccinate synthetase isozyme 1 isoform X2 [Chlorocebus sabaeus];XP_007942776.1//PREDICTED: adenylosuccinate synthetase isozyme 1 isoform X1 [Orycteropus afer afer]","4;1//3;2//1"]
[340156,5865,0.86,0.81,-0.086414751817473,0.811851509513151,"*",0.72657,"MYLK4","GO:0070062//extracellular exosome;GO:0005622//intracellular","GO:0005524//ATP binding;GO:0004687//myosin light chain kinase activity","GO:0018107//peptidyl-threonine phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0035556//intracellular signal transduction","K00907//myosin-light-chain kinase [EC:2.7.11.18]","NP_001334801.1//myosin light chain kinase family member 4 isoform 2 [Homo sapiens];XP_007972049.1//PREDICTED: myosin light chain kinase family member 4 isoform X3 [Chlorocebus sabaeus]","4;1//3"]
[22880,5216,7.95,7.49,-0.0859891417129666,0.448672966598246,"*",0.301044,"MORC2","GO:0005634//nucleus;GO:0005829//cytosol","GO:0008270//zinc ion binding","GO:0006631//fatty acid metabolic process","K04574//neurofilament heavy polypeptide","NP_001290185.1//MORC family CW-type zinc finger protein 2 isoform 1 [Homo sapiens];NP_001290186.1//MORC family CW-type zinc finger protein 2 isoform 2 [Homo sapiens]","3//A2MP1;2//1"]
[190,1591,44.39,41.84,-0.0853518570781518,0.384285881083242,"*",0.240738,"NR0B1","GO:0016020//membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0042788//polysomal ribosome;GO:0005737//cytoplasm","GO:0003707//steroid hormone receptor activity;GO:0003723//RNA binding;GO:0003677//DNA binding;GO:0050682//AF-2 domain binding;GO:0003714//transcription corepressor activity;GO:0042803//protein homodimerization activity;GO:0004879//nuclear receptor activity;GO:0035258//steroid hormone receptor binding;GO:0032448//DNA hairpin binding;GO:0019904//protein domain specific binding;GO:0043565//sequence-specific DNA binding;GO:0008134//transcription factor binding","GO:0030238//male sex determination;GO:0043433//negative regulation of DNA binding transcription factor activity;GO:0021854//hypothalamus development;GO:0007283//spermatogenesis;GO:0008584//male gonad development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0008406//gonad development;GO:0060008//Sertoli cell differentiation;GO:0021983//pituitary gland development;GO:0033144//negative regulation of intracellular steroid hormone receptor signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006694//steroid biosynthetic process;GO:0006351//transcription, DNA-templated;GO:0035902//response to immobilization stress;GO:0033327//Leydig cell differentiation;GO:0030325//adrenal gland development;GO:0045596//negative regulation of cell differentiation;GO:0008104//protein localization;GO:0006367//transcription initiation from RNA polymerase II promoter","K08562//nuclear receptor subfamily 0 group B member 1","NP_000466.2//nuclear receptor subfamily 0 group B member 1 [Homo sapiens]",4]
[51805,1265,5.6,5.28,-0.0848888975865129,0.799631376100275,"*",0.710878,"COQ3","GO:0005759//mitochondrial matrix;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0044596//3-demethylubiquinone-10 3-O-methyltransferase activity;GO:0008425//2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity;GO:0008171//O-methyltransferase activity;GO:0004395//hexaprenyldihydroxybenzoate methyltransferase activity;GO:0044595//decaprenyldihydroxybenzoate methyltransferase activity;GO:0008689//3-demethylubiquinone-9 3-O-methyltransferase activity","GO:0006071//glycerol metabolic process;GO:0010795//regulation of ubiquinone biosynthetic process;GO:0006744//ubiquinone biosynthetic process","K00591//polyprenyldihydroxybenzoate methyltransferase / 3-demethylubiquinol 3-O-methyltransferase [EC:2.1.1.114 2.1.1.64]","NP_059117.3//ubiquinone biosynthesis O-methyltransferase, mitochondrial [Homo sapiens]","3//A2MP1"]
[58533,3337,35.6,33.58,-0.0842750109167302,0.228275330150867,"*",0.1269276,"SNX6","GO:0097422//tubular endosome;GO:0030904//retromer complex;GO:0005634//nucleus;GO:0019898//extrinsic component of membrane;GO:0005622//intracellular;GO:0005764//lysosome;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0031901//early endosome membrane;GO:0030905//retromer, tubulation complex;GO:0005829//cytosol","GO:0034452//dynactin binding;GO:0046982//protein heterodimerization activity;GO:0034713//type I transforming growth factor beta receptor binding;GO:0042803//protein homodimerization activity;GO:0035091//phosphatidylinositol binding","GO:0016241//regulation of macroautophagy;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006886//intracellular protein transport;GO:0016050//vesicle organization;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0042147//retrograde transport, endosome to Golgi;GO:0006897//endocytosis;GO:0007175//negative regulation of epidermal growth factor-activated receptor activity","K17920//sorting nexin-5/6/32","XP_011375534.1//PREDICTED: sorting nexin-6 [Pteropus vampyrus];XP_012901678.1//PREDICTED: sorting nexin-6 [Mustela putorius furo]","4;3//A2MP1"]
[153768,4970,2.66,2.51,-0.0837388815504177,0.731673943723575,"*",0.62834,"PRELID2","GO:0005758//mitochondrial intermembrane space;GO:0005739//mitochondrion","GO:1990050//phosphatidic acid transporter activity","NA","K11447//histone demethylase [EC:1.14.11.-];K15696//RING finger protein 113B","NP_995318.1//PRELI domain-containing protein 2 isoform b [Homo sapiens];NP_892005.1//PRELI domain-containing protein 2 isoform a [Homo sapiens]","3//A2MP1;2//1;5"]
[25987,2720,220.22,207.85,-0.083402749961556,0.000634660567381174,"*",1.705248E-4,"TSKU","GO:0005615//extracellular space;GO:0005886//plasma membrane","GO:0004930//G-protein coupled receptor activity","GO:0021540//corpus callosum morphogenesis;GO:0010468//regulation of gene expression;GO:0030178//negative regulation of Wnt signaling pathway;GO:0021670//lateral ventricle development;GO:0021960//anterior commissure morphogenesis;GO:0061073//ciliary body morphogenesis;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway","K08130//tsukushi (leucine-rich repeat-containing protein 54)","XP_021560357.1//tsukushin [Neomonachus schauinslandi];NP_001305406.1//tsukushin isoform a precursor [Homo sapiens];XP_003254731.1//PREDICTED: tsukushin isoform X1 [Nomascus leucogenys]","1//3;3//A2MP1"]
[29907,1768,27.38,25.85,-0.0829581660556025,0.414786648318043,"*",0.271712,"SNX15","GO:0016020//membrane;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0030659//cytoplasmic vesicle membrane","GO:0035091//phosphatidylinositol binding","GO:0006886//intracellular protein transport;GO:0007165//signal transduction","K17927//sorting nexin-15","EAW74337.1//hCG23393, isoform CRA_b [Homo sapiens];EAW74336.1//hCG23393, isoform CRA_a [Homo sapiens]","4;3//A2MP1"]
[147949,2590,0.72,0.68,-0.0824621601919728,0.937695230982751,"*",0.88821,"ZNF583","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_012415365.1//PREDICTED: zinc finger protein 850 isoform X1 [Trichechus manatus latirostris]","1//3;2//1"]
[1717,2652,79.95,75.53,-0.0820482468220734,0.0936443087197513,"*",0.0433634,"DHCR7","GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005640//nuclear outer membrane","GO:0050661//NADP binding;GO:0047598//7-dehydrocholesterol reductase activity;GO:0009918//sterol delta7 reductase activity","GO:0030324//lung development;GO:0033489//cholesterol biosynthetic process via desmosterol;GO:0030154//cell differentiation;GO:0016132//brassinosteroid biosynthetic process;GO:0042127//regulation of cell proliferation;GO:0006695//cholesterol biosynthetic process;GO:0001568//blood vessel development;GO:0045540//regulation of cholesterol biosynthetic process;GO:0035264//multicellular organism growth;GO:0033490//cholesterol biosynthetic process via lathosterol;GO:0009791//post-embryonic development","K00213//7-dehydrocholesterol reductase [EC:1.3.1.21]","NP_001351.2//7-dehydrocholesterol reductase [Homo sapiens]","1//3;2//1"]
[9688,2922,27.4,25.89,-0.0817809279477777,0.370243683743445,"*",0.229832,"NUP93","GO:0016020//membrane;GO:0043657//host cell;GO:0005643//nuclear pore;GO:0031965//nuclear membrane;GO:0034399//nuclear periphery;GO:0005635//nuclear envelope","GO:0017056//structural constituent of nuclear pore","GO:0006406//mRNA export from nucleus;GO:0007077//mitotic nuclear envelope disassembly;GO:0016925//protein sumoylation;GO:0006110//regulation of glycolytic process;GO:0051028//mRNA transport;GO:0016973//poly(A)+ mRNA export from nucleus;GO:0072001//renal system development;GO:0015031//protein transport;GO:0090521//glomerular visceral epithelial cell migration;GO:0006998//nuclear envelope organization;GO:0051292//nuclear pore complex assembly;GO:0060391//positive regulation of SMAD protein import into nucleus;GO:0060964//regulation of gene silencing by miRNA;GO:0006409//tRNA export from nucleus;GO:0016032//viral process;GO:0060395//SMAD protein signal transduction;GO:1903206//negative regulation of hydrogen peroxide-induced cell death;GO:1900034//regulation of cellular response to heat;GO:0072015//glomerular visceral epithelial cell development;GO:0006606//protein import into nucleus;GO:0019083//viral transcription;GO:0075733//intracellular transport of virus","K14309//nuclear pore complex protein Nup93","NP_055484.3//nuclear pore complex protein Nup93 isoform 1 [Homo sapiens];XP_005977697.1//PREDICTED: nuclear pore complex protein Nup93 isoform X3 [Pantholops hodgsonii]","4;1//3;2//1"]
[5095,2531,3.85,3.64,-0.0809199953835675,0.759127025149528,"*",0.659472,"PCCA","GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0005739//mitochondrion","GO:0046872//metal ion binding;GO:0004075//biotin carboxylase activity;GO:0004658//propionyl-CoA carboxylase activity;GO:0005524//ATP binding;GO:0009374//biotin binding;GO:0019899//enzyme binding","GO:0019626//short-chain fatty acid catabolic process;GO:0006768//biotin metabolic process","K01965//propionyl-CoA carboxylase alpha chain [EC:6.4.1.3]","NP_001339538.1//propionyl-CoA carboxylase alpha chain, mitochondrial isoform h precursor [Homo sapiens];NP_000273.2//propionyl-CoA carboxylase alpha chain, mitochondrial isoform a precursor [Homo sapiens];NP_001171475.1//propionyl-CoA carboxylase alpha chain, mitochondrial isoform c precursor [Homo sapiens];CAA32763.1//propionyl-CoA carboxylase [Homo sapiens];NP_001339536.1//propionyl-CoA carboxylase alpha chain, mitochondrial isoform f [Homo sapiens];NP_001121164.1//propionyl-CoA carboxylase alpha chain, mitochondrial isoform b [Homo sapiens];NP_001339537.1//propionyl-CoA carboxylase alpha chain, mitochondrial isoform g [Homo sapiens];NP_001339534.1//propionyl-CoA carboxylase alpha chain, mitochondrial isoform d precursor [Homo sapiens];NP_001339535.1//propionyl-CoA carboxylase alpha chain, mitochondrial isoform e precursor [Homo sapiens]","1//3;3//A2MP1;2//1"]
[727957,4544,6.26,5.92,-0.0805654813036684,0.346850828282828,"*",0.210664,"MROH1","NA","NA","NA","K16628//collagen, type VII, alpha","XP_011515576.1//PREDICTED: maestro heat-like repeat-containing protein family member 1 isoform X6 [Homo sapiens];AAH92486.1//HEATR7A protein, partial [Homo sapiens];AAH57824.1//HEATR7A protein, partial [Homo sapiens];XP_011515575.1//PREDICTED: maestro heat-like repeat-containing protein family member 1 isoform X5 [Homo sapiens]","1//3;2//1"]
[121551,4198,9.63,9.11,-0.0800847440414089,0.00428636714004721,"*",1.36421E-3,"BTBD11","GO:0016021//integral component of membrane;GO:0005737//cytoplasm;GO:0019005//SCF ubiquitin ligase complex","GO:0031625//ubiquitin protein ligase binding;GO:0046982//protein heterodimerization activity","GO:0060395//SMAD protein signal transduction;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0030162//regulation of proteolysis;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process","K10483//BTB/POZ domain-containing protein 11","NP_001334872.1//ankyrin repeat and BTB/POZ domain-containing protein BTBD11 isoform c [Homo sapiens];NP_001334873.1//ankyrin repeat and BTB/POZ domain-containing protein BTBD11 isoform d [Homo sapiens];NP_001017523.1//ankyrin repeat and BTB/POZ domain-containing protein BTBD11 isoform b [Homo sapiens];NP_001018082.1//ankyrin repeat and BTB/POZ domain-containing protein BTBD11 isoform a [Homo sapiens]","1//3"]
[51661,2901,2.61,2.47,-0.0795387649852068,0.811422258087152,"*",0.7239,"FKBP7","NA","GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005509//calcium ion binding","NA","K09573//FK506-binding protein 7 [EC:5.2.1.8]","EAX11032.1//FK506 binding protein 7, isoform CRA_e [Homo sapiens]","1//3;2//1"]
[26585,3928,5.82,5.51,-0.0789668343371263,0.630974995585908,"*",0.474278,"GREM1","GO:0005615//extracellular space;GO:0009986//cell surface","GO:0030297//transmembrane receptor protein tyrosine kinase activator activity;GO:0005125//cytokine activity;GO:0048018//receptor ligand activity;GO:0043184//vascular endothelial growth factor receptor 2 binding;GO:0042803//protein homodimerization activity;GO:0036122//BMP binding;GO:0016015//morphogen activity","GO:2000273//positive regulation of receptor activity;GO:0010717//regulation of epithelial to mesenchymal transition;GO:0003257//positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation;GO:0030199//collagen fibril organization;GO:0051973//positive regulation of telomerase activity;GO:0002092//positive regulation of receptor internalization;GO:0090291//negative regulation of osteoclast proliferation;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0051893//regulation of focal adhesion assembly;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0045668//negative regulation of osteoblast differentiation;GO:1900158//negative regulation of bone mineralization involved in bone maturation;GO:0045766//positive regulation of angiogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0090191//negative regulation of branching involved in ureteric bud morphogenesis;GO:0007165//signal transduction;GO:0043066//negative regulation of apoptotic process;GO:0006915//apoptotic process;GO:0090190//positive regulation of branching involved in ureteric bud morphogenesis;GO:0060173//limb development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0009954//proximal/distal pattern formation;GO:2000727//positive regulation of cardiac muscle cell differentiation;GO:0060394//negative regulation of pathway-restricted SMAD protein phosphorylation;GO:0030514//negative regulation of BMP signaling pathway;GO:1900086//positive regulation of peptidyl-tyrosine autophosphorylation;GO:0030502//negative regulation of bone mineralization;GO:1900155//negative regulation of bone trabecula formation;GO:0002042//cell migration involved in sprouting angiogenesis;GO:0046851//negative regulation of bone remodeling;GO:0090027//negative regulation of monocyte chemotaxis;GO:0003337//mesenchymal to epithelial transition involved in metanephros morphogenesis;GO:0000902//cell morphogenesis;GO:0030308//negative regulation of cell growth;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0007267//cell-cell signaling;GO:0030326//embryonic limb morphogenesis;GO:0042346//positive regulation of NF-kappaB import into nucleus;GO:0033689//negative regulation of osteoblast proliferation;GO:0060676//ureteric bud formation;GO:0048263//determination of dorsal identity;GO:0032331//negative regulation of chondrocyte differentiation;GO:0008284//positive regulation of cell proliferation","K19558//neuroblastoma suppressor of tumorigenicity 1;K01645//cerberus 1","XP_003805004.1//PREDICTED: gremlin-1 [Pan paniscus];XP_022348550.1//gremlin-1 isoform X2 [Enhydra lutris kenyoni];XP_022348551.1//gremlin-1 isoform X3 [Enhydra lutris kenyoni]","6;1//3"]
[55502,1455,4.91,4.65,-0.0784923083192993,0.802847485223755,"*",0.71429,"HES6","GO:0005634//nucleus;GO:0005667//transcription factor complex","GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003712//transcription cofactor activity;GO:0008134//transcription factor binding;GO:0003700//DNA binding transcription factor activity;GO:0001227//transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0046983//protein dimerization activity","GO:0007399//nervous system development;GO:0030154//cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09087//hairy and enhancer of split 2/6/7","XP_011898349.1//PREDICTED: transcription cofactor HES-6 isoform X1 [Cercocebus atys];XP_005574844.1//PREDICTED: transcription cofactor HES-6 isoform X1 [Macaca fascicularis]","1//3;2//1;5"]
[9519,1338,13.7,12.98,-0.0778855098487504,0.669114453686776,"*",0.549902,"TBPL1","NA","NA","NA","K03120//transcription initiation factor TFIID TATA-box-binding protein","XP_006144394.1//PREDICTED: TATA box-binding protein-like protein 1 isoform X1 [Tupaia chinensis];XP_014706054.1//PREDICTED: TATA box-binding protein-like protein 1 isoform X2 [Equus asinus]","1//3;3//A2MP1"]
[23070,4137,8.81,8.35,-0.0773658215589991,0.596717132037021,"*",0.439936,"CMTR1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol","GO:0004483//mRNA (nucleoside-2'-O-)-methyltransferase activity;GO:0003676//nucleic acid binding","GO:0006370//7-methylguanosine mRNA capping;GO:0097309//cap1 mRNA methylation;GO:0080009//mRNA methylation","K14589//cap1 methyltransferase [EC:2.1.1.57]","NP_055865.1//cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 [Homo sapiens]","2//1"]
[125061,1760,20.67,19.6,-0.0766847344228769,0.591455469822082,"*",0.434946,"AFMID","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0016787//hydrolase activity;GO:0004061//arylformamidase activity","GO:0034354//'de novo' NAD biosynthetic process from tryptophan;GO:0019441//tryptophan catabolic process to kynurenine","K01432//arylformamidase [EC:3.5.1.9]","NP_001138998.1//kynurenine formamidase isoform 1 [Homo sapiens];NP_001010982.2//kynurenine formamidase isoform 2 [Homo sapiens]","4;2//1"]
[53340,955,11.93,11.32,-0.0757200848633457,0.778964992418824,"*",0.681826,"SPA17","GO:0016020//membrane;GO:0005929//cilium;GO:0009897//external side of plasma membrane;GO:0031514//motile cilium;GO:0097228//sperm principal piece;GO:0005737//cytoplasm;GO:0035686//sperm fibrous sheath","NA","GO:0007338//single fertilization;GO:0007283//spermatogenesis;GO:0003351//epithelial cilium movement;GO:0007339//binding of sperm to zona pellucida","K05970//sialate O-acetylesterase [EC:3.1.1.53];K20041//neuromodulin","NP_059121.1//sperm surface protein Sp17 [Homo sapiens]","3//A2MP1"]
[9489,2343,13.59,12.9,-0.0751743904567747,0.646436349248307,"*",0.489906,"PGS1","GO:0005783//endoplasmic reticulum;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0005524//ATP binding;GO:0005509//calcium ion binding;GO:0008444//CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity;GO:0017169//CDP-alcohol phosphatidyltransferase activity","GO:0032049//cardiolipin biosynthetic process;GO:0006655//phosphatidylglycerol biosynthetic process;GO:0046339//diacylglycerol metabolic process","K00995//CDP-diacylglycerol---glycerol-3-phosphate 3-phosphatidyltransferase [EC:2.7.8.5]","NP_077733.3//CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial precursor [Homo sapiens]",4]
[23107,2777,34.84,33.08,-0.0747853894275901,0.365900198544278,"*",0.226586,"MRPS27","GO:0005840//ribosome;GO:0005763//mitochondrial small ribosomal subunit;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0005737//cytoplasm","GO:0097177//mitochondrial ribosome binding;GO:0000049//tRNA binding;GO:0019843//rRNA binding","GO:0008283//cell proliferation;GO:0070131//positive regulation of mitochondrial translation;GO:0070126//mitochondrial translational termination;GO:0070125//mitochondrial translational elongation","K17406//small subunit ribosomal protein S27","NP_001273677.1//28S ribosomal protein S27, mitochondrial isoform 1 [Homo sapiens];NP_055899.2//28S ribosomal protein S27, mitochondrial isoform 2 [Homo sapiens]","1//3;2//1"]
[8330,460,0.2,0.19,-0.0740005814437769,1.00986424514087,"*",0.998548,"HIST1H2AK","NA","NA","NA","K11251//histone H2A","XP_019687248.1//PREDICTED: histone H2A type 1-E isoform X1 [Felis catus]","2//1"]
[2822,5858,1.4,1.33,-0.0740005814437767,0.817364673763306,"*",0.735444,"GPLD1","GO:0005765//lysosomal membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005622//intracellular;GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005578//proteinaceous extracellular matrix","GO:0004630//phospholipase D activity;GO:0017080//sodium channel regulator activity;GO:0004621//glycosylphosphatidylinositol phospholipase D activity","GO:0010867//positive regulation of triglyceride biosynthetic process;GO:0046470//phosphatidylcholine metabolic process;GO:0006501//C-terminal protein lipidation;GO:0008286//insulin receptor signaling pathway;GO:0035690//cellular response to drug;GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0010595//positive regulation of endothelial cell migration;GO:0010897//negative regulation of triglyceride catabolic process;GO:0071467//cellular response to pH;GO:0001503//ossification;GO:0097241//hematopoietic stem cell migration to bone marrow;GO:0010983//positive regulation of high-density lipoprotein particle clearance;GO:0035701//hematopoietic stem cell migration;GO:0043065//positive regulation of apoptotic process;GO:0002042//cell migration involved in sprouting angiogenesis;GO:0071277//cellular response to calcium ion;GO:1900076//regulation of cellular response to insulin stimulus;GO:0009749//response to glucose;GO:0008285//negative regulation of cell proliferation;GO:0010907//positive regulation of glucose metabolic process;GO:0045919//positive regulation of cytolysis;GO:0051044//positive regulation of membrane protein ectodomain proteolysis;GO:0070633//transepithelial transport;GO:0032869//cellular response to insulin stimulus;GO:0071397//cellular response to cholesterol;GO:0002062//chondrocyte differentiation;GO:0002430//complement receptor mediated signaling pathway;GO:0010694//positive regulation of alkaline phosphatase activity;GO:0071401//cellular response to triglyceride;GO:0006507//GPI anchor release;GO:0051047//positive regulation of secretion","K01127//glycosylphosphatidylinositol phospholipase D [EC:3.1.4.50]","NP_001494.2//phosphatidylinositol-glycan-specific phospholipase D precursor [Homo sapiens]","3//A2MP1"]
[112495,957,31.31,29.75,-0.0737338400560016,0.637012825121819,"*",0.515584,"GTF3C6","GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0000127//transcription factor TFIIIC complex","GO:0003677//DNA binding","GO:0042791//5S class rRNA transcription from RNA polymerase III type 1 promoter;GO:0042797//tRNA transcription from RNA polymerase III promoter;GO:0006351//transcription, DNA-templated;GO:0006383//transcription from RNA polymerase III promoter","K15203//general transcription factor 3C polypeptide 6","NP_612417.1//general transcription factor 3C polypeptide 6 [Homo sapiens]","3//A2MP1"]
[10884,1686,18.42,17.51,-0.0730939776577778,0.628716331853237,"*",0.505248,"MRPS30","GO:0005840//ribosome;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome","GO:0006412//translation;GO:0070126//mitochondrial translational termination;GO:0070125//mitochondrial translational elongation;GO:0006915//apoptotic process","K17409//small subunit ribosomal protein S30","NP_057724.2//39S ribosomal protein S30, mitochondrial [Homo sapiens]","3//A2MP1"]
[2720,2694,29.01,27.58,-0.0729278386840172,0.0653430376803314,"*",0.0286382,"GLB1","GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0005737//cytoplasm;GO:0005773//vacuole;GO:0048471//perinuclear region of cytoplasm;GO:0035578//azurophil granule lumen;GO:0005794//Golgi apparatus;GO:0005576//extracellular region;GO:1904813//ficolin-1-rich granule lumen;GO:0043202//lysosomal lumen","GO:0004308//exo-alpha-sialidase activity;GO:0004565//beta-galactosidase activity;GO:0016936//galactoside binding","GO:1904016//response to Thyroglobulin triiodothyronine;GO:0044262//cellular carbohydrate metabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0019388//galactose catabolic process;GO:0042340//keratan sulfate catabolic process;GO:0005975//carbohydrate metabolic process;GO:0043312//neutrophil degranulation;GO:0006027//glycosaminoglycan catabolic process;GO:0051413//response to cortisone","K12309//beta-galactosidase [EC:3.2.1.23]","NP_001129074.1//beta-galactosidase isoform c precursor [Homo sapiens];NP_000395.2//beta-galactosidase isoform a preproprotein [Homo sapiens];NP_001303969.1//beta-galactosidase isoform d precursor [Homo sapiens]","1//3;3//A2MP1;2//1"]
[64220,2772,22.43,21.33,-0.072545654745701,0.494583131256245,"*",0.340858,"STRA6","GO:0005887//integral component of plasma membrane;GO:0043234//protein complex;GO:0005886//plasma membrane","GO:0004872//receptor activity;GO:0034632//retinol transmembrane transporter activity","GO:0030540//female genitalia development;GO:0060539//diaphragm development;GO:0043010//camera-type eye development;GO:0001568//blood vessel development;GO:0048520//positive regulation of behavior;GO:0060900//embryonic camera-type eye formation;GO:0034633//retinol transport;GO:0003281//ventricular septum development;GO:0061038//uterus morphogenesis;GO:0007507//heart development;GO:0060323//head morphogenesis;GO:0050890//cognition;GO:0001523//retinoid metabolic process;GO:0043585//nose morphogenesis;GO:0060322//head development;GO:0030325//adrenal gland development;GO:0007631//feeding behavior;GO:0048566//embryonic digestive tract development;GO:0061205//paramesonephric duct development;GO:0030324//lung development;GO:0001822//kidney development;GO:0048745//smooth muscle tissue development;GO:0048546//digestive tract morphogenesis;GO:0061156//pulmonary artery morphogenesis;GO:0003184//pulmonary valve morphogenesis;GO:0097070//ductus arteriosus closure;GO:0043583//ear development;GO:0061143//alveolar primary septum development;GO:0061029//eyelid development in camera-type eye;GO:0060426//lung vasculature development;GO:0007612//learning;GO:0042297//vocal learning;GO:0048844//artery morphogenesis;GO:0048589//developmental growth;GO:0060325//face morphogenesis;GO:0048286//lung alveolus development;GO:0050905//neuromuscular process","K06236//collagen, type I, alpha;K19720//collagen, type III, alpha","BAH13848.1//unnamed protein product [Homo sapiens];NP_001136092.1//stimulated by retinoic acid gene 6 protein homolog isoform c [Homo sapiens];CAD97655.1//hypothetical protein, partial [Homo sapiens];NP_001185969.1//stimulated by retinoic acid gene 6 protein homolog isoform d [Homo sapiens]","1//3;3//A2MP1"]
[6591,2112,1.44,1.37,-0.0718929184817856,0.887308540307361,"*",0.824096,"SNAI2","NA","NA","NA","K05706//snail 2","XP_004679945.1//PREDICTED: zinc finger protein SNAI2 [Condylura cristata]",4]
[65988,3529,3.94,3.75,-0.071305034073133,0.683196993871529,"*",0.565282,"ZNF747","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_004057554.2//PREDICTED: zinc finger protein 768 isoform X3 [Gorilla gorilla gorilla];XP_018868176.1//PREDICTED: zinc finger protein 768 isoform X2 [Gorilla gorilla gorilla];XP_010339158.1//PREDICTED: zinc finger protein 768 [Saimiri boliviensis boliviensis]","1//3;3//A2MP1"]
[7818,2075,46.55,44.33,-0.0704978052808913,0.444527706559371,"*",0.2974,"DAP3","GO:0005654//nucleoplasm;GO:0005761//mitochondrial ribosome;GO:0005763//mitochondrial small ribosomal subunit;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0015935//small ribosomal subunit","GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005525//GTP binding","GO:0097190//apoptotic signaling pathway;GO:0070126//mitochondrial translational termination;GO:0006915//apoptotic process;GO:0070125//mitochondrial translational elongation","K17408//small subunit ribosomal protein S29","NP_001186780.1//28S ribosomal protein S29, mitochondrial isoform 3 [Homo sapiens];NP_004623.1//28S ribosomal protein S29, mitochondrial isoform 1 [Homo sapiens];NP_001186779.1//28S ribosomal protein S29, mitochondrial isoform 2 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[124512,1002,31.63,30.13,-0.0700928829229304,0.642471901736973,"*",0.486258,"METTL23","GO:0005634//nucleus;GO:0043234//protein complex;GO:0016021//integral component of membrane;GO:0005737//cytoplasm","GO:0008168//methyltransferase activity;GO:0031072//heat shock protein binding;GO:0008134//transcription factor binding","GO:0050890//cognition;GO:0045944//positive regulation of transcription from RNA polymerase II promoter","K21804//protein N-lysine methyltransferase METTL21A [EC:2.1.1.-];K00884//N-acetylglucosamine kinase [EC:2.7.1.59];K11323//histone arginine demethylase JMJD6 [EC:1.14.11.-];K21806//protein N-lysine methyltransferase METTL21D [EC:2.1.1.-]","XP_011897729.1//PREDICTED: methyltransferase-like protein 23 isoform X3 [Cercocebus atys];AAH33998.2//C17orf95 protein, partial [Homo sapiens];XP_016788457.1//PREDICTED: methyltransferase-like protein 23 isoform X1 [Pan troglodytes];XP_016879635.1//PREDICTED: methyltransferase-like protein 23 isoform X2 [Homo sapiens];XP_016788459.1//PREDICTED: methyltransferase-like protein 23 isoform X2 [Pan troglodytes]","4;1//3;2//1"]
[6118,1664,29.75,28.35,-0.0695409332530769,0.509289381765869,"*",0.354596,"RPA2","GO:0035861//site of double-strand break;GO:0016605//PML body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000784//nuclear chromosome, telomeric region;GO:0016604//nuclear body;GO:0000785//chromatin;GO:0005662//DNA replication factor A complex","GO:0003697//single-stranded DNA binding;GO:0003684//damaged DNA binding;GO:0047485//protein N-terminus binding;GO:0031625//ubiquitin protein ligase binding;GO:0019903//protein phosphatase binding;GO:0098505//G-rich strand telomeric DNA binding;GO:0019899//enzyme binding","GO:0034502//protein localization to chromosome;GO:0031571//mitotic G1 DNA damage checkpoint;GO:0006284//base-excision repair;GO:0006260//DNA replication;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0006296//nucleotide-excision repair, DNA incision, 5'-to lesion;GO:0006295//nucleotide-excision repair, DNA incision, 3'-to lesion;GO:0010569//regulation of double-strand break repair via homologous recombination;GO:0006289//nucleotide-excision repair;GO:0042769//DNA damage response, detection of DNA damage;GO:0036297//interstrand cross-link repair;GO:0006293//nucleotide-excision repair, preincision complex stabilization;GO:0033683//nucleotide-excision repair, DNA incision;GO:0006298//mismatch repair;GO:2000001//regulation of DNA damage checkpoint;GO:1901796//regulation of signal transduction by p53 class mediator;GO:0006294//nucleotide-excision repair, preincision complex assembly;GO:0019985//translesion synthesis;GO:1900034//regulation of cellular response to heat;GO:0042276//error-prone translesion synthesis;GO:0070987//error-free translesion synthesis;GO:0000082//G1/S transition of mitotic cell cycle;GO:0006297//nucleotide-excision repair, DNA gap filling;GO:0032201//telomere maintenance via semi-conservative replication;GO:0000724//double-strand break repair via homologous recombination;GO:0000723//telomere maintenance","K10739//replication factor A2","NP_001284487.1//replication protein A 32 kDa subunit isoform 3 [Homo sapiens];NP_001342058.1//replication protein A 32 kDa subunit isoform 4 [Homo sapiens];XP_004025327.2//PREDICTED: LOW QUALITY PROTEIN: replication protein A 32 kDa subunit [Gorilla gorilla gorilla];NP_001125362.2//replication protein A 32 kDa subunit [Pongo abelii]","4;1//3"]
[25972,1197,26.38,25.15,-0.0688861645586552,0.650980088219473,"*",0.530312,"UNC50","GO:0030173//integral component of Golgi membrane;GO:0016021//integral component of membrane;GO:0005637//nuclear inner membrane;GO:0000139//Golgi membrane","GO:0003723//RNA binding","GO:0006810//transport;GO:0007166//cell surface receptor signaling pathway;GO:0015031//protein transport","NA","NP_001317283.1//protein unc-50 homolog isoform 1 [Homo sapiens];XP_006712466.1//PREDICTED: protein unc-50 homolog isoform X1 [Homo sapiens]","6;1//3"]
[7480,2370,2.16,2.06,-0.0683869749802501,0.866405694200829,"*",0.797794,"WNT10B","NA","NA","NA","K01357//wingless-type MMTV integration site family, member 10","XP_005324955.1//protein Wnt-10b [Ictidomys tridecemlineatus]","3//A2MP1"]
[56262,4310,14.86,14.18,-0.0675765832990801,0.57068778814802,"*",0.414172,"LRRC8A","GO:0034702//ion channel complex;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0042802//identical protein binding;GO:0005225//volume-sensitive anion channel activity","GO:0006884//cell volume homeostasis;GO:0007165//signal transduction;GO:0006970//response to osmotic stress;GO:0098656//anion transmembrane transport","K22038//volume-regulated anion channel","XP_015989254.1//PREDICTED: LOW QUALITY PROTEIN: volume-regulated anion channel subunit LRRC8A [Rousettus aegyptiacus]","1//3;3//A2MP1"]
[84720,4044,32.39,30.93,-0.0665416347059221,0.584944937238494,"*",0.42884,"PIGO","GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0051377//mannose-ethanolamine phosphotransferase activity;GO:0003824//catalytic activity","GO:0006506//GPI anchor biosynthetic process;GO:0008152//metabolic process","K05288//phosphatidylinositol glycan, class O","XP_009186845.1//GPI ethanolamine phosphate transferase 3 isoform X3 [Papio anubis];NP_690577.2//GPI ethanolamine phosphate transferase 3 isoform 2 [Homo sapiens];NP_116023.2//GPI ethanolamine phosphate transferase 3 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[9514,1650,13.25,12.66,-0.0657149549095826,0.703907471314234,"*",0.589116,"GAL3ST1","GO:0016020//membrane;GO:0005887//integral component of plasma membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0008146//sulfotransferase activity;GO:0001733//galactosylceramide sulfotransferase activity","GO:0042552//myelination;GO:0009247//glycolipid biosynthetic process;GO:0006487//protein N-linked glycosylation;GO:0007283//spermatogenesis;GO:0006682//galactosylceramide biosynthetic process","K01019//galactosylceramide sulfotransferase [EC:2.8.2.11]","NP_001305038.1//galactosylceramide sulfotransferase isoform 3 [Homo sapiens];XP_011528820.1//PREDICTED: galactosylceramide sulfotransferase isoform X1 [Homo sapiens]","1//3;2//1"]
[55861,1016,9.24,8.83,-0.0654794137675916,0.751457253109633,"*",0.650504,"DBNDD2","GO:0030672//synaptic vesicle membrane","NA","GO:0006469//negative regulation of protein kinase activity;GO:0031175//neuron projection development","K20189//dysbindin","EAW75852.1//chromosome 20 open reading frame 35, isoform CRA_f, partial [Homo sapiens];NP_060948.3//dysbindin domain-containing protein 2 isoform e [Homo sapiens];NP_001041691.2//dysbindin domain-containing protein 2 isoform d [Homo sapiens];NP_001041690.2//dysbindin domain-containing protein 2 isoform c [Homo sapiens]","1//3;3//A2MP1;2//1"]
[57150,2416,1.59,1.52,-0.0649554418407697,0.903435551807229,"*",0.844956,"SMIM8","NA","NA","NA","K05673//ATP-binding cassette, subfamily C (CFTR/MRP), member 4","XP_008992989.1//PREDICTED: small integral membrane protein 8 isoform X5 [Callithrix jacchus];XP_009240335.1//PREDICTED: small integral membrane protein 8 isoform X2 [Pongo abelii]","1//3;2//1;5"]
[10576,1962,147.47,141.01,-0.0646240173371619,0.131057759512629,"*",0.0646428,"CCT2","NA","NA","NA","K09494//T-complex protein 1 subunit beta","XP_010357039.1//PREDICTED: T-complex protein 1 subunit beta [Rhinopithecus roxellana];XP_011905050.1//PREDICTED: T-complex protein 1 subunit beta [Cercocebus atys]","1//3;2//1"]
[6505,3757,0.46,0.44,-0.0641303374197157,0.935879393674739,"*",0.885494,"SLC1A1","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005887//integral component of plasma membrane;GO:0016324//apical plasma membrane;GO:0005886//plasma membrane","GO:0005313//L-glutamate transmembrane transporter activity;GO:0016595//glutamate binding;GO:0015108//chloride transmembrane transporter activity;GO:0046872//metal ion binding;GO:0033229//cysteine transmembrane transporter activity;GO:0005314//high-affinity glutamate transmembrane transporter activity;GO:0015501//glutamate:sodium symporter activity;GO:0015171//amino acid transmembrane transporter activity","GO:0070779//D-aspartate import;GO:0010460//positive regulation of heart rate;GO:0089711//L-glutamate transmembrane transport;GO:0140016//D-aspartate import across plasma membrane;GO:0098712//L-glutamate import across plasma membrane;GO:0051260//protein homooligomerization;GO:0006811//ion transport;GO:0051938//L-glutamate import;GO:0042883//cysteine transport;GO:0140009//L-aspartate import across plasma membrane;GO:0007268//chemical synaptic transmission;GO:1902476//chloride transmembrane transport;GO:0014047//glutamate secretion","K05612//solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter), member 1","NP_004161.4//excitatory amino acid transporter 3 [Homo sapiens]",5]
[192111,2826,50.02,47.85,-0.0639861328075821,0.308200772808132,"*",0.1822116,"PGAM5","GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane","GO:0009400//signal transducer, downstream of receptor, with serine/threonine phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0016791//phosphatase activity;GO:0032403//protein complex binding;GO:0005096//GTPase activator activity","GO:0070266//necroptotic process;GO:0043547//positive regulation of GTPase activity;GO:0016311//dephosphorylation;GO:0016236//macroautophagy","K15637//serine/threonine-protein phosphatase PGAM5 [EC:3.1.3.16]","NP_001164014.1//serine/threonine-protein phosphatase PGAM5, mitochondrial isoform 1 [Homo sapiens];NP_001164015.1//serine/threonine-protein phosphatase PGAM5, mitochondrial isoform 2 [Homo sapiens];NP_612642.2//serine/threonine-protein phosphatase PGAM5, mitochondrial isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[28232,3992,11.61,11.11,-0.0635091554764746,0.720111197205084,"*",0.606464,"SLCO3A1","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005215//transporter activity;GO:0015347//sodium-independent organic anion transmembrane transporter activity","GO:0043252//sodium-independent organic anion transport;GO:0006811//ion transport;GO:0015732//prostaglandin transport","K14353//solute carrier organic anion transporter family, member 3A","NP_037404.2//solute carrier organic anion transporter family member 3A1 isoform 1 [Homo sapiens];NP_001138516.1//solute carrier organic anion transporter family member 3A1 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[388282,1298,13.42,12.85,-0.0626163121189431,0.772881930905963,"*",0.67505,"LOC388282","NA","NA","NA","NA","AAP13354.1//unknown [Homo sapiens]","1//3"]
[54458,1262,292.49,280.16,-0.062136312061407,0.11327989222499,"*",0.054087,"PRR13","GO:0005654//nucleoplasm;GO:0005829//cytosol","NA","NA","K05740//diaphanous 1;K09291//nucleoprotein TPR;K02184//formin 2;K05748//WAS protein family, member 2","XP_011785898.1//PREDICTED: proline-rich protein 13 isoform X3 [Colobus angolensis palliatus];EAW96702.1//proline rich 13, isoform CRA_a [Homo sapiens]","3//A2MP1;2//1"]
[51649,1498,31.3,29.99,-0.0616811349512405,0.653590441716781,"*",0.496678,"MRPS23","GO:0005840//ribosome;GO:0031965//nuclear membrane;GO:0045111//intermediate filament cytoskeleton;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome","GO:0006412//translation;GO:0070126//mitochondrial translational termination;GO:0070125//mitochondrial translational elongation","K17402//small subunit ribosomal protein S23","NP_057154.2//28S ribosomal protein S23, mitochondrial [Homo sapiens]","3//A2MP1"]
[112936,3744,12.51,11.99,-0.0612501307515961,0.624844833528448,"*",0.501198,"VPS26B","GO:0005768//endosome;GO:0030904//retromer complex;GO:0005770//late endosome;GO:0005829//cytosol;GO:0030906//retromer, cargo-selective complex;GO:0005769//early endosome","GO:0008565//protein transporter activity","GO:0016241//regulation of macroautophagy;GO:0006886//intracellular protein transport;GO:0042147//retrograde transport, endosome to Golgi","K18466//vacuolar protein sorting-associated protein 26","NP_443107.1//vacuolar protein sorting-associated protein 26B [Homo sapiens]",4]
[6747,4313,46.04,44.14,-0.0608012038526164,0.134895494779319,"*",0.0669664,"SSR3","GO:0005784//Sec61 translocon complex;GO:0005622//intracellular;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","NA","GO:0006614//SRP-dependent cotranslational protein targeting to membrane","K13251//translocon-associated protein subunit gamma","NP_001295126.1//translocon-associated protein subunit gamma isoform 1 [Homo sapiens];XP_012366145.1//PREDICTED: translocon-associated protein subunit gamma isoform X1 [Nomascus leucogenys];XP_010138580.1//PREDICTED: translocon-associated protein subunit gamma, partial [Buceros rhinoceros silvestris];NP_009038.1//translocon-associated protein subunit gamma isoform 2 [Homo sapiens]","1//3;4"]
[342945,4627,6.11,5.86,-0.0602717153964816,0.680819476298652,"*",0.562846,"ZSCAN22","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_022347978.1//zinc finger and SCAN domain-containing protein 22-like isoform X1 [Enhydra lutris kenyoni];XP_014721031.1//PREDICTED: LOW QUALITY PROTEIN: zinc finger and SCAN domain-containing protein 22 [Equus asinus]","1//3;2//1"]
[1953,7450,2.21,2.12,-0.0599821048282323,0.769062653942742,"*",0.670992,"MEGF6","NA","NA","NA","K02258//cytochrome c oxidase assembly protein subunit 11","BAE19678.1//hypothetical protein, partial [Homo sapiens]","3//A2MP1"]
[5599,5850,3.45,3.31,-0.0597651448583137,0.567703904671445,"*",0.41158,"MAPK8","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0002102//podosome;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005739//mitochondrion;GO:0005737//cytoplasm;GO:0043005//neuron projection","GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0042826//histone deacetylase binding;GO:0035033//histone deacetylase regulator activity;GO:0004705//JUN kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004672//protein kinase activity;GO:0004707//MAP kinase activity;GO:0019899//enzyme binding","GO:0034198//cellular response to amino acid starvation;GO:0007258//JUN phosphorylation;GO:0071260//cellular response to mechanical stimulus;GO:0071222//cellular response to lipopolysaccharide;GO:2000017//positive regulation of determination of dorsal identity;GO:0071310//cellular response to organic substance;GO:0048666//neuron development;GO:0043065//positive regulation of apoptotic process;GO:0032091//negative regulation of protein binding;GO:1902595//regulation of DNA replication origin binding;GO:0071276//cellular response to cadmium ion;GO:0070301//cellular response to hydrogen peroxide;GO:0009612//response to mechanical stimulus;GO:1900740//positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway;GO:0006468//protein phosphorylation;GO:0043066//negative regulation of apoptotic process;GO:0010628//positive regulation of gene expression;GO:2001235//positive regulation of apoptotic signaling pathway;GO:0042752//regulation of circadian rhythm;GO:0018107//peptidyl-threonine phosphorylation;GO:0046686//response to cadmium ion;GO:0001764//neuron migration;GO:0018105//peptidyl-serine phosphorylation;GO:0032880//regulation of protein localization;GO:0090045//positive regulation of deacetylase activity;GO:0097150//neuronal stem cell population maintenance;GO:0051403//stress-activated MAPK cascade;GO:0010468//regulation of gene expression;GO:0071803//positive regulation of podosome assembly;GO:0034614//cellular response to reactive oxygen species;GO:0006950//response to stress;GO:0001503//ossification;GO:0061833//protein localization to tricellular tight junction;GO:0097300//programmed necrotic cell death;GO:0016241//regulation of macroautophagy;GO:0071732//cellular response to nitric oxide;GO:0051247//positive regulation of protein metabolic process;GO:0009411//response to UV;GO:0051090//regulation of DNA binding transcription factor activity;GO:0048511//rhythmic process;GO:0048813//dendrite morphogenesis;GO:0031281//positive regulation of cyclase activity;GO:0007254//JNK cascade;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0048263//determination of dorsal identity","K04440//c-Jun N-terminal kinase [EC:2.7.11.24]","XP_006897773.1//PREDICTED: mitogen-activated protein kinase 8-like isoform X5 [Elephantulus edwardii];XP_006897772.1//PREDICTED: mitogen-activated protein kinase 8-like isoform X4 [Elephantulus edwardii];NP_001265476.1//mitogen-activated protein kinase 8 isoform beta2 [Homo sapiens];XP_006897771.1//PREDICTED: mitogen-activated protein kinase 8-like isoform X3 [Elephantulus edwardii];EDL24854.1//mitogen activated protein kinase 8, isoform CRA_c, partial [Mus musculus];NP_001310249.1//mitogen-activated protein kinase 8 isoform 6 [Homo sapiens]","1//3;3//A2MP1"]
[5444,2567,0.25,0.24,-0.0588936890535686,1.01903040005119,"*",0.996958,"PON1","GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0072562//blood microparticle;GO:0034364//high-density lipoprotein particle;GO:0005576//extracellular region;GO:0034366//spherical high-density lipoprotein particle","GO:0004063//aryldialkylphosphatase activity;GO:0005509//calcium ion binding;GO:0004064//arylesterase activity;GO:0102007//acyl-L-homoserine-lactone lactonohydrolase activity;GO:0042803//protein homodimerization activity;GO:0005543//phospholipid binding","GO:0010875//positive regulation of cholesterol efflux;GO:0046395//carboxylic acid catabolic process;GO:0009605//response to external stimulus;GO:0046470//phosphatidylcholine metabolic process;GO:0019439//aromatic compound catabolic process;GO:0008203//cholesterol metabolic process;GO:0032411//positive regulation of transporter activity;GO:0046434//organophosphate catabolic process;GO:0009636//response to toxic substance;GO:0019372//lipoxygenase pathway;GO:0031667//response to nutrient levels;GO:0070542//response to fatty acid;GO:0051099//positive regulation of binding;GO:1902617//response to fluoride","K01045//arylesterase / paraoxonase [EC:3.1.1.2 3.1.8.1]","NP_000437.3//serum paraoxonase/arylesterase 1 precursor [Homo sapiens]",6]
[83696,6901,4.79,4.6,-0.0583917947918052,0.689880137598069,"*",0.572496,"TRAPPC9","GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0030008//TRAPP complex;GO:0005802//trans-Golgi network;GO:0000139//Golgi membrane","GO:0017112//Rab guanyl-nucleotide exchange factor activity","GO:0030182//neuron differentiation;GO:0021987//cerebral cortex development;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0048208//COPII vesicle coating;GO:0061024//membrane organization","K20306//trafficking protein particle complex subunit 9","XP_011515628.1//PREDICTED: trafficking protein particle complex subunit 9 isoform X1 [Homo sapiens];NP_113654.4//trafficking protein particle complex subunit 9 isoform a [Homo sapiens]","1//3;3//A2MP1;7"]
[55748,5089,16.81,16.15,-0.0577855596548802,0.552514759220598,"*",0.397628,"CNDP2","GO:0070062//extracellular exosome;GO:0005654//nucleoplasm;GO:0005829//cytosol","GO:0004180//carboxypeptidase activity;GO:0103046//alanylglutamate dipeptidase activity;GO:0046872//metal ion binding;GO:0008237//metallopeptidase activity;GO:0102008//cytosolic dipeptidase activity;GO:0016805//dipeptidase activity","GO:0006750//glutathione biosynthetic process","K08660//cytosolic nonspecific dipeptidase [EC:3.4.13.18]","NP_001161971.1//cytosolic non-specific dipeptidase isoform 2 [Homo sapiens];XP_012636662.1//cytosolic non-specific dipeptidase [Microcebus murinus]","1//3;2//1"]
[1846,5646,64.14,61.64,-0.0573574919268614,0.149112907612457,"*",0.0755366,"DUSP4","GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0008330//protein tyrosine/threonine phosphatase activity;GO:0017017//MAP kinase tyrosine/serine/threonine phosphatase activity;GO:1990439//MAP kinase serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0016791//phosphatase activity","GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0035970//peptidyl-threonine dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0001706//endoderm formation;GO:0016311//dephosphorylation;GO:0000188//inactivation of MAPK activity","K04459//dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48]","NP_476499.1//dual specificity protein phosphatase 4 isoform 2 [Homo sapiens];AAB35870.1//threonine, tyrosine phosphatase, partial [Homo sapiens]","6;3//A2MP1"]
[10602,5164,11.93,11.47,-0.0567286516794029,0.452094227433464,"*",0.304132,"CDC42EP3","GO:0012505//endomembrane system;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0005519//cytoskeletal regulatory protein binding;GO:0017049//GTP-Rho binding;GO:0005096//GTPase activator activity","GO:0007266//Rho protein signal transduction;GO:0007165//signal transduction;GO:0031274//positive regulation of pseudopodium assembly;GO:0030838//positive regulation of actin filament polymerization;GO:0008360//regulation of cell shape","K19720//collagen, type III, alpha","NP_006440.2//cdc42 effector protein 3 [Homo sapiens]","4;1//3"]
[476,3754,56.25,54.09,-0.0564911988382639,0.112152969176192,"*",0.0534366,"ATP1A1","GO:0016021//integral component of membrane","GO:0005391//sodium:potassium-exchanging ATPase activity;GO:0046872//metal ion binding;GO:0005524//ATP binding","NA","K01539//sodium/potassium-transporting ATPase subunit alpha [EC:3.6.3.9]","P30714.2//RecName: Full=Sodium/potassium-transporting ATPase subunit alpha-1; Short=Na(+)/K(+) ATPase alpha-1 subunit; AltName: Full=Sodium pump subunit alpha-1; Flags: Precursor","1//3;7"]
[57761,2147,58.48,56.24,-0.056346716879902,0.487705914769623,"*",0.335294,"TRIB3","GO:0031965//nuclear membrane;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0031434//mitogen-activated protein kinase kinase binding;GO:0003714//transcription corepressor activity;GO:0004860//protein kinase inhibitor activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0031625//ubiquitin protein ligase binding;GO:0055106//ubiquitin-protein transferase regulator activity;GO:0019901//protein kinase binding","GO:0034976//response to endoplasmic reticulum stress;GO:0043405//regulation of MAP kinase activity;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0051443//positive regulation of ubiquitin-protein transferase activity;GO:0032092//positive regulation of protein binding;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0019216//regulation of lipid metabolic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006468//protein phosphorylation;GO:0045599//negative regulation of fat cell differentiation;GO:0006351//transcription, DNA-templated;GO:0032869//cellular response to insulin stimulus;GO:0006469//negative regulation of protein kinase activity;GO:0045717//negative regulation of fatty acid biosynthetic process;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0010827//regulation of glucose transport","K19518//tribbles homolog 3","XP_003273513.1//PREDICTED: tribbles homolog 3 isoform X1 [Nomascus leucogenys];NP_066981.2//tribbles homolog 3 isoform 1 [Homo sapiens];NP_001288130.1//tribbles homolog 3 isoform 2 [Homo sapiens]","4;1//3"]
[317762,5671,10.55,10.15,-0.055763271522009,0.647484389994221,"*",0.490984,"CCDC85C","GO:0005923//bicellular tight junction;GO:0043296//apical junction complex","NA","GO:0021987//cerebral cortex development","K13864//solute carrier family 7 (cationic amino acid transporter), member 2;K16758//coiled-coil domain-containing protein 85B","NP_001138467.1//coiled-coil domain-containing protein 85C [Homo sapiens]","1//3"]
[80381,2964,36.38,35.01,-0.0553784812229823,0.259370377709522,"*",0.1480168,"CD276","GO:0070062//extracellular exosome;GO:0009897//external side of plasma membrane;GO:0016021//integral component of membrane","GO:0005102//receptor binding","GO:0042110//T cell activation;GO:0008283//cell proliferation;GO:0045078//positive regulation of interferon-gamma biosynthetic process;GO:0042102//positive regulation of T cell proliferation;GO:0006955//immune response;GO:0050776//regulation of immune response","K06746//immune costimulatory protein B7-H3","NP_079516.1//CD276 antigen isoform b precursor [Homo sapiens];XP_015308533.1//PREDICTED: CD276 antigen isoform X1 [Macaca fascicularis];NP_001019907.1//CD276 antigen isoform a precursor [Homo sapiens]","1//3;2//1"]
[339745,5741,1.87,1.8,-0.055041363557962,0.846286651207464,"*",0.772222,"SPOPL","GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0031463//Cul3-RING ubiquitin ligase complex;GO:0019005//SCF ubiquitin ligase complex","GO:0031625//ubiquitin protein ligase binding","GO:0031397//negative regulation of protein ubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0030162//regulation of proteolysis;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process","K10523//speckle-type POZ protein","XP_020746107.1//speckle-type POZ protein-like isoform X1 [Odocoileus virginianus texanus]","2//1"]
[10395,5870,8.08,7.78,-0.0545851377656029,0.429253933649289,"*",0.2835,"DLC1","GO:0005634//nucleus;GO:0030864//cortical actin cytoskeleton;GO:0005901//caveola;GO:0005925//focal adhesion;GO:0005829//cytosol;GO:0032587//ruffle membrane;GO:0005737//cytoplasm","GO:0008289//lipid binding;GO:0042169//SH2 domain binding;GO:0005096//GTPase activator activity","GO:0035307//positive regulation of protein dephosphorylation;GO:0021575//hindbrain morphogenesis;GO:0032956//regulation of actin cytoskeleton organization;GO:0003007//heart morphogenesis;GO:0051497//negative regulation of stress fiber assembly;GO:1900119//positive regulation of execution phase of apoptosis;GO:0008285//negative regulation of cell proliferation;GO:0048041//focal adhesion assembly;GO:0007165//signal transduction;GO:0030036//actin cytoskeleton organization;GO:0030336//negative regulation of cell migration;GO:0008360//regulation of cell shape;GO:0051895//negative regulation of focal adhesion assembly;GO:0006915//apoptotic process;GO:0030900//forebrain development;GO:0035023//regulation of Rho protein signal transduction;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0001843//neural tube closure;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0035024//negative regulation of Rho protein signal transduction","K20632//deleted in liver cancer protein","NP_079043.3//rho GTPase-activating protein 7 isoform 3 [Homo sapiens];NP_006085.2//rho GTPase-activating protein 7 isoform 2 [Homo sapiens];AAH54511.1//Deleted in liver cancer 1 [Homo sapiens];NP_872584.2//rho GTPase-activating protein 7 isoform 1 [Homo sapiens];NP_001303597.1//rho GTPase-activating protein 7 isoform 5 [Homo sapiens]","4;1//3;3//A2MP1;2//1"]
[1641,9150,0.27,0.26,-0.0544477840223765,1.02176443529185,"*",0.99394,"DCX","GO:0005856//cytoskeleton;GO:0005875//microtubule associated complex;GO:0005874//microtubule;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005737//cytoplasm;GO:0043005//neuron projection","GO:0008017//microtubule binding;GO:0019901//protein kinase binding","GO:0007399//nervous system development;GO:0048675//axon extension;GO:0021860//pyramidal neuron development;GO:0021766//hippocampus development;GO:0035556//intracellular signal transduction;GO:0007417//central nervous system development;GO:0048813//dendrite morphogenesis;GO:0001764//neuron migration;GO:0021952//central nervous system projection neuron axonogenesis;GO:0021819//layer formation in cerebral cortex","K16579//neuronal migration protein doublecortin","XP_022271525.1//neuronal migration protein doublecortin isoform X1 [Canis lupus familiaris];NP_000546.2//neuronal migration protein doublecortin isoform a [Homo sapiens];XP_022271528.1//neuronal migration protein doublecortin isoform X4 [Canis lupus familiaris];XP_016799488.1//PREDICTED: neuronal migration protein doublecortin isoform X3 [Pan troglodytes];XP_002832043.2//PREDICTED: neuronal migration protein doublecortin isoform X2 [Pongo abelii]","1//3;3//A2MP1;2//1"]
[27315,1817,22.58,21.75,-0.0540300851495477,0.70435173315384,"*",0.589576,"PGAP2","GO:0005634//nucleus;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0000139//Golgi membrane","GO:0008565//protein transporter activity","GO:1902230//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage;GO:0006506//GPI anchor biosynthetic process;GO:0042770//signal transduction in response to DNA damage;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator","K03006//DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6];K15263//cell growth-regulating nucleolar protein;K21125//mucin-5AC","XP_022263440.1//post-GPI attachment to proteins factor 2 isoform X1 [Canis lupus familiaris];XP_011518295.2//PREDICTED: post-GPI attachment to proteins factor 2 isoform X4 [Homo sapiens];NP_001269967.1//post-GPI attachment to proteins factor 2 isoform 9 [Homo sapiens];NP_001333326.1//post-GPI attachment to proteins factor 2 isoform 12 [Homo sapiens];NP_001269969.1//post-GPI attachment to proteins factor 2 isoform 11 [Homo sapiens];OWK17835.1//PGAP2 [Cervus elaphus hippelaphus];NP_001243166.1//post-GPI attachment to proteins factor 2 isoform 5 [Homo sapiens];NP_001243165.1//post-GPI attachment to proteins factor 2 isoform 4 [Homo sapiens];NP_001269968.1//post-GPI attachment to proteins factor 2 isoform 10 [Homo sapiens];NP_001138910.1//post-GPI attachment to proteins factor 2 isoform 2 [Homo sapiens];NP_001333331.1//post-GPI attachment to proteins factor 2 isoform 15 [Homo sapiens];ELK32341.1//Post-GPI attachment to proteins factor 2, partial [Myotis davidii]","1//3;3//A2MP1;2//1"]
[219844,1892,12.33,11.88,-0.0536379636020732,0.758389601787774,"*",0.658594,"HYLS1","GO:0005929//cilium;GO:0005814//centriole;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005813//centrosome;GO:0005886//plasma membrane;GO:0005737//cytoplasm","NA","GO:0060271//cilium assembly","K16472//hydrolethalus syndrome protein 1","XP_015291404.1//PREDICTED: hydrolethalus syndrome protein 1 homolog isoform X2 [Macaca fascicularis];XP_008019603.1//PREDICTED: hydrolethalus syndrome protein 1 isoform X1 [Chlorocebus sabaeus]","1//3;2//1"]
[8226,2149,13.72,13.23,-0.0524674198941355,0.901148541982175,"*",0.841858,"PUDP","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:1990738//pseudouridine 5'-phosphatase activity;GO:0016787//hydrolase activity;GO:0016791//phosphatase activity","GO:0008152//metabolic process;GO:0043097//pyrimidine nucleoside salvage;GO:0009117//nucleotide metabolic process","K17623//pseudouridine 5'-phosphatase [EC:3.1.3.96]","NP_001171607.1//pseudouridine-5'-phosphatase isoform d [Homo sapiens];NP_001129037.1//pseudouridine-5'-phosphatase isoform a [Homo sapiens];NP_001171606.1//pseudouridine-5'-phosphatase isoform c [Homo sapiens];NP_036212.3//pseudouridine-5'-phosphatase isoform b [Homo sapiens]","1//3;4"]
[23086,9875,1.68,1.62,-0.0524674198941355,0.915684494205408,"*",0.860654,"EXPH5","GO:0005768//endosome;GO:0005622//intracellular","GO:0017137//Rab GTPase binding","GO:0050714//positive regulation of protein secretion;GO:0003334//keratinocyte development;GO:0006886//intracellular protein transport;GO:0045921//positive regulation of exocytosis;GO:0071985//multivesicular body sorting pathway","K22236//exophilin-5","NP_001294948.1//exophilin-5 isoform 2 [Homo sapiens];NP_055880.2//exophilin-5 isoform 1 [Homo sapiens]","1//3;2//1"]
[80028,6245,14.48,13.97,-0.0517295816737423,0.0644224496638535,"*",0.0281944,"FBXL18","NA","NA","NA","K10284//F-box and leucine-rich repeat protein 18","NP_001308142.1//F-box/LRR-repeat protein 18 isoform 1 [Homo sapiens];XP_003895742.3//F-box/LRR-repeat protein 18 isoform X1 [Papio anubis]","1//3;5"]
[1723,2438,10.88,10.5,-0.0512892286968546,0.781725912521441,"*",0.684732,"DHODH","GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0043025//neuronal cell body","GO:0004152//dihydroorotate dehydrogenase activity;GO:0010181//FMN binding;GO:0008144//drug binding;GO:0048039//ubiquinone binding","GO:0007595//lactation;GO:0042493//response to drug;GO:0007565//female pregnancy;GO:0046134//pyrimidine nucleoside biosynthetic process;GO:1903576//response to L-arginine;GO:0044205//'de novo' UMP biosynthetic process;GO:0043065//positive regulation of apoptotic process;GO:0042594//response to starvation;GO:0031000//response to caffeine;GO:0090140//regulation of mitochondrial fission;GO:0006207//'de novo' pyrimidine nucleobase biosynthetic process","K00254//dihydroorotate dehydrogenase [EC:1.3.5.2]","NP_001352.2//dihydroorotate dehydrogenase (quinone), mitochondrial [Homo sapiens]",4]
[23132,9916,2.58,2.49,-0.0512253233551731,0.710398979777628,"*",0.595972,"RAD54L2","NA","GO:0005524//ATP binding","NA","K10876//RAD54-like protein 2 [EC:3.6.4.12]","XP_021583201.1//helicase ARIP4 isoform X3 [Ictidomys tridecemlineatus];XP_001169759.1//PREDICTED: helicase ARIP4 isoform X1 [Pan troglodytes]","1//3;3//A2MP1"]
[54857,2374,0.29,0.28,-0.0506260730699678,1.01922750172833,"*",0.996768,"GDPD2","GO:0005884//actin filament;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0030027//lamellipodium;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0047394//glycerophosphoinositol inositolphosphodiesterase activity;GO:0008889//glycerophosphodiester phosphodiesterase activity","GO:0090527//actin filament reorganization;GO:0045669//positive regulation of osteoblast differentiation;GO:0006629//lipid metabolic process","K01124//glycerophosphoinositol inositolphosphodiesterase [EC:3.1.4.43]","NP_001164663.1//glycerophosphoinositol inositolphosphodiesterase GDPD2 isoform 1 [Homo sapiens];NP_060181.2//glycerophosphoinositol inositolphosphodiesterase GDPD2 isoform 2 [Homo sapiens];XP_009437508.1//PREDICTED: glycerophosphoinositol inositolphosphodiesterase GDPD2 isoform X2 [Pan troglodytes]","1//3;3//A2MP1"]
[109703458,3266,4.71,4.55,-0.0498605145267246,0.699779011542497,"*",0.584478,"HTD2","GO:0005759//mitochondrial matrix;GO:0005730//nucleolus;GO:0005739//mitochondrion","GO:0018812//3-hydroxyacyl-CoA dehydratase activity","GO:0046949//fatty-acyl-CoA biosynthetic process;GO:0006631//fatty acid metabolic process","K12581//CCR4-NOT transcription complex subunit 7/8;K14529//ribonuclease P protein subunit RPP14 [EC:3.1.26.5]","NP_001335643.1//hydroxyacyl-thioester dehydratase type 2, mitochondrial [Homo sapiens]","1//3"]
[51226,939,8.01,7.74,-0.0494686762642998,0.894481739936832,"*",0.833278,"COPZ2","GO:0030126//COPI vesicle coat;GO:0030133//transport vesicle;GO:0005829//cytosol;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005801//cis-Golgi network;GO:0000139//Golgi membrane","NA","GO:0006886//intracellular protein transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0015031//protein transport","K20472//coatomer subunit zeta","NP_057513.1//coatomer subunit zeta-2 [Homo sapiens]","3//A2MP1"]
[9441,3184,3.9,3.77,-0.0489096004809464,0.859247614319809,"*",0.788836,"MED26","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016592//mediator complex","GO:0003713//transcription coactivator activity;GO:0001104//RNA polymerase II transcription cofactor activity","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006367//transcription initiation from RNA polymerase II promoter","K15169//mediator of RNA polymerase II transcription subunit 26","NP_004822.2//mediator of RNA polymerase II transcription subunit 26 [Homo sapiens]","3//A2MP1"]
[2098,1208,45.55,44.05,-0.0483090348816371,0.687179981874481,"*",0.56961,"ESD","GO:0070062//extracellular exosome;GO:0005788//endoplasmic reticulum lumen;GO:0031410//cytoplasmic vesicle;GO:0005737//cytoplasm","GO:0047374//methylumbelliferyl-acetate deacetylase activity;GO:0042802//identical protein binding;GO:0052689//carboxylic ester hydrolase activity;GO:0018738//S-formylglutathione hydrolase activity;GO:0016788//hydrolase activity, acting on ester bonds","GO:0046294//formaldehyde catabolic process;GO:1901687//glutathione derivative biosynthetic process","K01070//S-formylglutathione hydrolase [EC:3.1.2.12]","XP_009190178.1//S-formylglutathione hydrolase isoform X1 [Papio anubis]","1//3"]
[23396,4955,10.11,9.78,-0.0478766269507809,0.676869785562633,"*",0.558818,"PIP5K1C","GO:0010008//endosome membrane;GO:0005654//nucleoplasm;GO:0005925//focal adhesion;GO:0098793//presynapse;GO:0001931//uropod;GO:0032587//ruffle membrane;GO:0001891//phagocytic cup;GO:0005829//cytosol","GO:0016307//phosphatidylinositol phosphate kinase activity;GO:0052812//phosphatidylinositol-3,4-bisphosphate 5-kinase activity;GO:0005524//ATP binding;GO:0016308//1-phosphatidylinositol-4-phosphate 5-kinase activity;GO:0052811//1-phosphatidylinositol-3-phosphate 4-kinase activity","GO:0048488//synaptic vesicle endocytosis;GO:0030593//neutrophil chemotaxis;GO:0030036//actin cytoskeleton organization;GO:0014066//regulation of phosphatidylinositol 3-kinase signaling;GO:0072583//clathrin-dependent endocytosis;GO:0006661//phosphatidylinositol biosynthetic process;GO:0061024//membrane organization;GO:0098609//cell-cell adhesion;GO:0016079//synaptic vesicle exocytosis;GO:0034333//adherens junction assembly;GO:0006909//phagocytosis","K00889//1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]","XP_007992983.1//PREDICTED: phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X1 [Chlorocebus sabaeus];XP_010365580.1//PREDICTED: phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X1 [Rhinopithecus roxellana]","1//3;2//1"]
[84282,2086,20.2,19.55,-0.0471866854444423,0.657951678076422,"*",0.537886,"RNF135","GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0043021//ribonucleoprotein complex binding;GO:0004842//ubiquitin-protein transferase activity","GO:0032728//positive regulation of interferon-beta production;GO:0016567//protein ubiquitination;GO:0016579//protein deubiquitination;GO:0045088//regulation of innate immune response;GO:0032480//negative regulation of type I interferon production;GO:0045087//innate immune response","K16272//E3 ubiquitin-protein ligase RNF135 [EC:2.3.2.27]","XP_002827271.2//PREDICTED: E3 ubiquitin-protein ligase RNF135 isoform X1 [Pongo abelii];XP_003778828.2//PREDICTED: E3 ubiquitin-protein ligase RNF135 isoform X3 [Pongo abelii];XP_009249753.1//PREDICTED: E3 ubiquitin-protein ligase RNF135 isoform X2 [Pongo abelii]","1//3;3//A2MP1"]
[2395,7170,4.76,4.61,-0.0461948228786054,0.774637681358848,"*",0.676632,"FXN","GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0005739//mitochondrion","GO:0034986//iron chaperone activity;GO:0051537//2 iron, 2 sulfur cluster binding;GO:0004322//ferroxidase activity;GO:0008199//ferric iron binding;GO:0051536//iron-sulfur cluster binding;GO:0008198//ferrous iron binding","GO:0006879//cellular iron ion homeostasis;GO:0051349//positive regulation of lyase activity;GO:0030307//positive regulation of cell growth;GO:0044281//small molecule metabolic process;GO:0090201//negative regulation of release of cytochrome c from mitochondria;GO:0006783//heme biosynthetic process;GO:0009792//embryo development ending in birth or egg hatching;GO:0006119//oxidative phosphorylation;GO:0046621//negative regulation of organ growth;GO:0040015//negative regulation of multicellular organism growth;GO:0018283//iron incorporation into metallo-sulfur cluster;GO:0043085//positive regulation of catalytic activity;GO:0070301//cellular response to hydrogen peroxide;GO:0016540//protein autoprocessing;GO:0010039//response to iron ion;GO:0043066//negative regulation of apoptotic process;GO:1904234//positive regulation of aconitate hydratase activity;GO:0009060//aerobic respiration;GO:0006811//ion transport;GO:0007005//mitochondrion organization;GO:0010722//regulation of ferrochelatase activity;GO:0016226//iron-sulfur cluster assembly;GO:0007628//adult walking behavior;GO:0019230//proprioception;GO:1904231//positive regulation of succinate dehydrogenase activity;GO:0008284//positive regulation of cell proliferation","K19054//frataxin [EC:1.16.3.1]","NP_000135.2//frataxin, mitochondrial isoform 1 preproprotein [Homo sapiens];NP_852090.1//frataxin, mitochondrial isoform 2 preproprotein [Homo sapiens]","4;2//1"]
[79583,2925,4.15,4.02,-0.0459158350553588,0.892237145623235,"*",0.830796,"TMEM231","GO:0060170//ciliary membrane;GO:0035869//ciliary transition zone;GO:0016021//integral component of membrane;GO:0036038//MKS complex","NA","GO:0043010//camera-type eye development;GO:0001701//in utero embryonic development;GO:0042733//embryonic digit morphogenesis;GO:0060271//cilium assembly;GO:0001944//vasculature development;GO:0032880//regulation of protein localization;GO:0007224//smoothened signaling pathway;GO:0060563//neuroepithelial cell differentiation","K19362//transmembrane protein 231","XP_008953160.1//PREDICTED: transmembrane protein 231 isoform X1 [Pan paniscus];NP_001070886.1//transmembrane protein 231 isoform 2 [Homo sapiens]","2//1"]
[22938,2155,34.92,33.83,-0.045750381835452,0.632551595415118,"*",0.5113,"SNW1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000785//chromatin;GO:0016607//nuclear speck;GO:0016363//nuclear matrix;GO:0005737//cytoplasm;GO:0071013//catalytic step 2 spliceosome;GO:0005681//spliceosomal complex;GO:0016604//nuclear body;GO:0071014//post-mRNA release spliceosomal complex;GO:0071141//SMAD protein complex","GO:0042809//vitamin D receptor binding;GO:0003723//RNA binding;GO:0003714//transcription corepressor activity;GO:0042974//retinoic acid receptor binding;GO:0035257//nuclear hormone receptor binding;GO:0050681//androgen receptor binding;GO:0003713//transcription coactivator activity;GO:0005112//Notch binding;GO:0046332//SMAD binding;GO:0019899//enzyme binding","GO:0048385//regulation of retinoic acid receptor signaling pathway;GO:0043923//positive regulation by host of viral transcription;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0000350//generation of catalytic spliceosome for second transesterification step;GO:0070564//positive regulation of vitamin D receptor signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0051571//positive regulation of histone H3-K4 methylation;GO:0000398//mRNA splicing, via spliceosome;GO:0048384//retinoic acid receptor signaling pathway;GO:0006351//transcription, DNA-templated;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0016032//viral process;GO:0071300//cellular response to retinoic acid;GO:0048026//positive regulation of mRNA splicing, via spliceosome;GO:0050769//positive regulation of neurogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0070562//regulation of vitamin D receptor signaling pathway;GO:0007219//Notch signaling pathway;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0014010//Schwann cell proliferation","K06063//SNW domain-containing protein 1","XP_006157174.1//PREDICTED: SNW domain-containing protein 1 [Tupaia chinensis];XP_008061519.1//SNW domain-containing protein 1 isoform X1 [Carlito syrichta]","1//3;2//1"]
[80019,1711,14.09,13.66,-0.0447141280195461,0.813697960011186,"*",0.72863,"UBTD1","NA","GO:0043130//ubiquitin binding","NA","NA","NP_079230.1//ubiquitin domain-containing protein 1 [Homo sapiens]",4]
[5516,1987,42.8,41.5,-0.0444994601668597,0.63293356914976,"*",0.511688,"PPP2CB","GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0000775//chromosome, centromeric region","GO:0046872//metal ion binding;GO:0004721//phosphoprotein phosphatase activity","NA","K04382//serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]","XP_021092390.1//serine/threonine-protein phosphatase 2A catalytic subunit beta isoform [Heterocephalus glaber]","1//3"]
[27352,2930,6.35,6.16,-0.0438262409646267,0.760172846774194,"*",0.660904,"SGSM3","GO:0012505//endomembrane system;GO:0005921//gap junction;GO:0005829//cytosol","GO:0017137//Rab GTPase binding;GO:0005096//GTPase activator activity","GO:0006886//intracellular protein transport;GO:0090630//activation of GTPase activity;GO:0032483//regulation of Rab protein signal transduction;GO:0045732//positive regulation of protein catabolic process;GO:0031338//regulation of vesicle fusion;GO:0043547//positive regulation of GTPase activity;GO:0007050//cell cycle arrest;GO:0032486//Rap protein signal transduction;GO:0048227//plasma membrane to endosome transport","K20176//small G protein signaling modulator 3","NP_056520.2//small G protein signaling modulator 3 isoform 1 [Homo sapiens];NP_001336969.1//small G protein signaling modulator 3 isoform 4 [Homo sapiens];NP_001336973.1//small G protein signaling modulator 3 isoform 8 [Homo sapiens];NP_001336968.1//small G protein signaling modulator 3 isoform 3 [Homo sapiens];NP_001336971.1//small G protein signaling modulator 3 isoform 6 [Homo sapiens];NP_001288778.1//small G protein signaling modulator 3 isoform 2 [Homo sapiens];NP_001336970.1//small G protein signaling modulator 3 isoform 5 [Homo sapiens]","1//3;5"]
[79644,4089,5.02,4.87,-0.0437655918684296,0.847253071604938,"*",0.773316,"SRD5A3","GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0102389//polyprenol reductase activity;GO:0016628//oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;GO:0047751//cholestenone 5-alpha-reductase activity;GO:0003865//3-oxo-5-alpha-steroid 4-dehydrogenase activity","GO:0016095//polyprenol catabolic process;GO:0006486//protein glycosylation;GO:0006489//dolichyl diphosphate biosynthetic process;GO:0019348//dolichol metabolic process;GO:0006488//dolichol-linked oligosaccharide biosynthetic process;GO:0006702//androgen biosynthetic process","K12345//3-oxo-5-alpha-steroid 4-dehydrogenase 3 [EC:1.3.1.22 1.3.1.94]","NP_078868.1//polyprenol reductase [Homo sapiens]",4]
[131474,1494,19.81,19.22,-0.043620544115736,0.902290395501406,"*",0.843772,"CHCHD4","GO:0005758//mitochondrial intermembrane space;GO:0005739//mitochondrion","GO:0015035//protein disulfide oxidoreductase activity","GO:0051084//'de novo' posttranslational protein folding;GO:0022417//protein maturation by protein folding;GO:0045041//protein import into mitochondrial intermembrane space","K17782//mitochondrial intermembrane space import and assembly protein 40","NP_001091972.1//mitochondrial intermembrane space import and assembly protein 40 isoform 1 [Homo sapiens];NP_653237.1//mitochondrial intermembrane space import and assembly protein 40 isoform 2 [Homo sapiens]","1//3;2//1"]
[54883,3112,16.55,16.06,-0.0433593241772658,0.732050800029614,"*",0.618994,"CWC25","GO:0005654//nucleoplasm;GO:0016607//nuclear speck","NA","GO:0000398//mRNA splicing, via spliceosome","K12182//hepatocyte growth factor-regulated tyrosine kinase substrate;K01064//wingless-type MMTV integration site family, member 9","NP_060218.1//pre-mRNA-splicing factor CWC25 homolog [Homo sapiens]",4]
[101928991,4432,1.69,1.64,-0.0433274316641005,0.89650148768539,"*",0.836282,"CCDC92B","NA","NA","NA","K16452//coiled-coil domain-containing protein 92","XP_011727190.1//PREDICTED: coiled-coil domain-containing protein 92 [Macaca nemestrina]","1//3"]
[54758,1934,12.89,12.51,-0.0431704741958312,0.745972963440237,"*",0.645056,"KLHDC4","NA","NA","NA","K03006//DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6];K13172//serine/arginine repetitive matrix protein 2","NP_001171783.1//kelch domain-containing protein 4 isoform 3 [Homo sapiens];NP_060036.2//kelch domain-containing protein 4 isoform 1 [Homo sapiens];NP_001171785.1//kelch domain-containing protein 4 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[80737,2914,0.68,0.66,-0.043068721891886,0.941307761166458,"*",0.893164,"VWA7","GO:0005576//extracellular region","NA","NA","K17341//hemicentin","NP_079534.2//von Willebrand factor A domain-containing protein 7 precursor [Homo sapiens]","2//1"]
[285,5114,0.34,0.33,-0.043068721891886,1.02144074143582,"*",0.994904,"ANGPT2","GO:0005634//nucleus;GO:0005615//extracellular space;GO:0042995//cell projection;GO:0005576//extracellular region;GO:0005886//plasma membrane","GO:0046872//metal ion binding;GO:0030971//receptor tyrosine kinase binding;GO:0005102//receptor binding","GO:0031100//animal organ regeneration;GO:0014070//response to organic cyclic compound;GO:0060135//maternal process involved in female pregnancy;GO:0050928//negative regulation of positive chemotaxis;GO:0071363//cellular response to growth factor stimulus;GO:0009749//response to glucose;GO:0045766//positive regulation of angiogenesis;GO:0072012//glomerulus vasculature development;GO:0009612//response to mechanical stimulus;GO:0007165//signal transduction;GO:0001525//angiogenesis;GO:0050900//leukocyte migration;GO:0016525//negative regulation of angiogenesis;GO:0014823//response to activity;GO:0048014//Tie signaling pathway;GO:0001666//response to hypoxia;GO:0007281//germ cell development;GO:0009314//response to radiation;GO:0010812//negative regulation of cell-substrate adhesion;GO:0043537//negative regulation of blood vessel endothelial cell migration","K05466//angiopoietin 2","XP_010379683.1//PREDICTED: angiopoietin-2 isoform X2 [Rhinopithecus roxellana];XP_010379682.1//PREDICTED: angiopoietin-2 isoform X1 [Rhinopithecus roxellana];XP_010379684.1//PREDICTED: angiopoietin-2 isoform X3 [Rhinopithecus roxellana]","1//3;2//1"]
[55347,2785,11.23,10.9,-0.0430297927363124,0.782323025512756,"*",0.685304,"ABHD10","GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0005739//mitochondrion","GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0016787//hydrolase activity;GO:0102390//mycophenolic acid acyl-glucuronide esterase activity","GO:0052695//cellular glucuronidation;GO:0019391//glucuronoside catabolic process","K13702//abhydrolase domain-containing protein 10 [EC:3.1.1.93]","NP_001258998.1//mycophenolic acid acyl-glucuronide esterase, mitochondrial isoform 2 [Homo sapiens];NP_060864.1//mycophenolic acid acyl-glucuronide esterase, mitochondrial isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[219854,4003,4.43,4.3,-0.042970038965558,0.861459432426906,"*",0.791298,"TMEM218","GO:0005929//cilium;GO:0016021//integral component of membrane","NA","NA","NA","NP_001245168.1//transmembrane protein 218 isoform 1 [Homo sapiens]","1//3;2//1"]
[81559,2715,17.04,16.54,-0.0429661010545636,0.740187790986283,"*",0.638478,"TRIM11","GO:0005622//intracellular","GO:0008270//zinc ion binding","NA","K10650//tripartite motif-containing protein 11 [EC:2.3.2.27]","XP_011941598.1//PREDICTED: E3 ubiquitin-protein ligase TRIM11 isoform X1 [Cercocebus atys]","2//1"]
[5550,2943,16.7,16.21,-0.0429640118438729,0.732927718449432,"*",0.629692,"PREP","NA","NA","NA","K01322//prolyl oligopeptidase [EC:3.4.21.26]","XP_003898012.3//prolyl endopeptidase isoform X1 [Papio anubis]",4]
[123207,847,42.08,40.85,-0.0427986262592565,0.785650211458112,"*",0.694514,"C15orf40","NA","NA","NA","K09131//uncharacterized protein","NP_653198.2//UPF0235 protein C15orf40 isoform a [Homo sapiens];NP_001153585.1//UPF0235 protein C15orf40 isoform b [Homo sapiens];NP_001153588.1//UPF0235 protein C15orf40 isoform e [Homo sapiens];NP_001153587.1//UPF0235 protein C15orf40 isoform d [Homo sapiens];NP_001153586.1//UPF0235 protein C15orf40 isoform c [Homo sapiens]","1//3;2//1"]
[80304,3897,7.53,7.31,-0.042778458719491,0.710315382249757,"*",0.595724,"WDCP","NA","GO:0019900//kinase binding","GO:0051259//protein oligomerization","NA","NP_079479.1//WD repeat and coiled-coil-containing protein isoform 1 [Homo sapiens];NP_001135791.1//WD repeat and coiled-coil-containing protein isoform 2 [Homo sapiens]","1//3;2//1"]
[51184,1580,12.36,12,-0.0426443374084937,0.685764278676137,"*",0.568136,"GPN3","GO:0043234//protein complex;GO:0005622//intracellular","GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:1990022//RNA polymerase III complex localization to nucleus;GO:0044376//RNA polymerase II complex import to nucleus","K06883//uncharacterized protein","XP_005253953.3//PREDICTED: GPN-loop GTPase 3 isoform X1 [Homo sapiens];NP_001157844.1//GPN-loop GTPase 3 isoform 2 [Homo sapiens];XP_009424519.2//PREDICTED: GPN-loop GTPase 3 isoform X1 [Pan troglodytes]","1//3;3//A2MP1"]
[26020,6930,38.18,37.07,-0.0425649875847818,0.407427639161377,"*",0.265208,"LRP10","GO:0016020//membrane;GO:0005905//clathrin-coated pit;GO:0016021//integral component of membrane","GO:0005041//low-density lipoprotein receptor activity","GO:0006869//lipid transport;GO:0048839//inner ear development;GO:0006629//lipid metabolic process","K20050//low-density lipoprotein receptor-related protein 3/10/12","XP_004054968.1//PREDICTED: low-density lipoprotein receptor-related protein 10 [Gorilla gorilla gorilla]","1//3;4"]
[3320,3376,552.5,536.51,-0.0423694029053918,0.00989321907870874,"*",0.003415,"HSP90AA1","GO:0034774//secretory granule lumen;GO:0016020//membrane;GO:0032587//ruffle membrane;GO:0042470//melanosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005576//extracellular region;GO:1904813//ficolin-1-rich granule lumen;GO:0043202//lysosomal lumen;GO:0005886//plasma membrane;GO:0070062//extracellular exosome;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0043209//myelin sheath;GO:0043234//protein complex;GO:0071682//endocytic vesicle lumen","GO:0030235//nitric-oxide synthase regulator activity;GO:0003723//RNA binding;GO:0005524//ATP binding;GO:1990782//protein tyrosine kinase binding;GO:0070182//DNA polymerase binding;GO:0004713//protein tyrosine kinase activity;GO:0000166//nucleotide binding;GO:0016887//ATPase activity;GO:0042826//histone deacetylase binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0023026//MHC class II protein complex binding;GO:0030911//TPR domain binding;GO:0051082//unfolded protein binding;GO:0051020//GTPase binding;GO:0097718//disordered domain specific binding","GO:0006986//response to unfolded protein;GO:0006950//response to stress;GO:0051973//positive regulation of telomerase activity;GO:0043335//protein unfolding;GO:0006839//mitochondrial transport;GO:0046677//response to antibiotic;GO:0097711//ciliary basal body-plasma membrane docking;GO:0007004//telomere maintenance via telomerase;GO:0043312//neutrophil degranulation;GO:0006457//protein folding;GO:1905323//telomerase holoenzyme complex assembly;GO:0031396//regulation of protein ubiquitination;GO:0045040//protein import into mitochondrial outer membrane;GO:0007165//signal transduction;GO:0009409//response to cold;GO:0043254//regulation of protein complex assembly;GO:0038128//ERBB2 signaling pathway;GO:0009408//response to heat;GO:1900034//regulation of cellular response to heat;GO:0051131//chaperone-mediated protein complex assembly;GO:0010389//regulation of G2/M transition of mitotic cell cycle;GO:0006898//receptor-mediated endocytosis;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0050999//regulation of nitric-oxide synthase activity;GO:0000086//G2/M transition of mitotic cell cycle;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0061684//chaperone-mediated autophagy;GO:0042026//protein refolding;GO:0050821//protein stabilization","K04079//molecular chaperone HtpG","NP_001017963.2//heat shock protein HSP 90-alpha isoform 1 [Homo sapiens];XP_010967090.1//PREDICTED: heat shock protein HSP 90-alpha [Camelus bactrianus]","3//A2MP1;2//1"]
[5777,2283,10.03,9.74,-0.0423279285298384,0.810010852249596,"*",0.722438,"PTPN6","GO:1904724//tertiary granule lumen;GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0035580//specific granule lumen;GO:0042105//alpha-beta T cell receptor complex;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0005911//cell-cell junction;GO:0005829//cytosol;GO:0043234//protein complex;GO:0005576//extracellular region","GO:0050839//cell adhesion molecule binding;GO:0001784//phosphotyrosine residue binding;GO:0005001//transmembrane receptor protein tyrosine phosphatase activity;GO:0017124//SH3 domain binding;GO:0004725//protein tyrosine phosphatase activity;GO:0042169//SH2 domain binding;GO:0019901//protein kinase binding","GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:0043407//negative regulation of MAP kinase activity;GO:0050860//negative regulation of T cell receptor signaling pathway;GO:0042130//negative regulation of T cell proliferation;GO:0033277//abortive mitotic cell cycle;GO:0008285//negative regulation of cell proliferation;GO:0045577//regulation of B cell differentiation;GO:0030154//cell differentiation;GO:0042267//natural killer cell mediated cytotoxicity;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0006915//apoptotic process;GO:0050859//negative regulation of B cell receptor signaling pathway;GO:0002244//hematopoietic progenitor cell differentiation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0051279//regulation of release of sequestered calcium ion into cytosol;GO:0035556//intracellular signal transduction;GO:0030168//platelet activation;GO:0031295//T cell costimulation;GO:0008283//cell proliferation;GO:0030220//platelet formation;GO:0043312//neutrophil degranulation;GO:0006470//protein dephosphorylation;GO:0050732//negative regulation of peptidyl-tyrosine phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0007186//G-protein coupled receptor signaling pathway;GO:0050853//B cell receptor signaling pathway;GO:0035855//megakaryocyte development;GO:0002924//negative regulation of humoral immune response mediated by circulating immunoglobulin;GO:0050900//leukocyte migration;GO:0060338//regulation of type I interferon-mediated signaling pathway;GO:0070527//platelet aggregation;GO:0033630//positive regulation of cell adhesion mediated by integrin;GO:0008284//positive regulation of cell proliferation","K05697//tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]","NP_536859.1//tyrosine-protein phosphatase non-receptor type 6 isoform 3 [Homo sapiens];NP_536858.1//tyrosine-protein phosphatase non-receptor type 6 isoform 2 [Homo sapiens];XP_011838424.1//PREDICTED: tyrosine-protein phosphatase non-receptor type 6 isoform X1 [Mandrillus leucophaeus]","4;3//A2MP1;5"]
[51752,4935,4.87,4.73,-0.0420815887429469,0.79450366986456,"*",0.705076,"ERAP1","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005576//extracellular region;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane","GO:0004175//endopeptidase activity;GO:0005151//interleukin-1, Type II receptor binding;GO:0042277//peptide binding;GO:0008235//metalloexopeptidase activity;GO:0070006//metalloaminopeptidase activity;GO:0005138//interleukin-6 receptor binding;GO:0004177//aminopeptidase activity;GO:0008270//zinc ion binding","GO:0008217//regulation of blood pressure;GO:0006509//membrane protein ectodomain proteolysis;GO:0007165//signal transduction;GO:0001525//angiogenesis;GO:0007267//cell-cell signaling;GO:0045088//regulation of innate immune response;GO:0043171//peptide catabolic process;GO:0019885//antigen processing and presentation of endogenous peptide antigen via MHC class I;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0002250//adaptive immune response;GO:0045444//fat cell differentiation;GO:0045766//positive regulation of angiogenesis;GO:0009617//response to bacterium","K09604//adipocyte-derived leucine aminopeptidase [EC:3.4.11.-]","NP_001035548.1//endoplasmic reticulum aminopeptidase 1 isoform b precursor [Homo sapiens];NP_057526.3//endoplasmic reticulum aminopeptidase 1 isoform a precursor [Homo sapiens]","4;1//3;2//1"]
[7444,1804,21.62,21,-0.0419771951811654,0.612658560873216,"*",0.45679,"VRK2","GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0043234//protein complex;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005737//cytoplasm","GO:0004674//protein serine/threonine kinase activity;GO:0019904//protein domain specific binding;GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0019901//protein kinase binding","GO:0006468//protein phosphorylation;GO:0043408//regulation of MAPK cascade;GO:0016032//viral process;GO:0008360//regulation of cell shape;GO:2000659//regulation of interleukin-1-mediated signaling pathway;GO:0046777//protein autophosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0034599//cellular response to oxidative stress","K08816//vaccinia related kinase [EC:2.7.11.1]","NP_001123955.1//serine/threonine-protein kinase VRK2 isoform 3 [Homo sapiens];AAO73047.1//vaccinia related kinase 2 isoform 1 [Homo sapiens];NP_006287.2//serine/threonine-protein kinase VRK2 isoform 1 [Homo sapiens]","6;1//3;2//1"]
[140699,2043,2.1,2.04,-0.0418201756946271,1.02135751653878,"*",0.991626,"MROH8","NA","NA","NA","K04257//olfactory receptor;K14793//ribosomal RNA-processing protein 9","NP_998797.2//protein MROH8 isoform 3 [Homo sapiens];NP_998796.1//protein MROH8 isoform 2 [Homo sapiens];NP_689716.4//protein MROH8 isoform 1 [Homo sapiens]","2//1;5"]
[8533,1797,77.3,75.1,-0.0416555064105757,0.365849981599434,"*",0.226532,"COPS3","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0008180//COP9 signalosome;GO:0005737//cytoplasm","NA","GO:0043687//post-translational protein modification;GO:0000338//protein deneddylation;GO:0007165//signal transduction;GO:0000715//nucleotide-excision repair, DNA damage recognition;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0009416//response to light stimulus;GO:0001701//in utero embryonic development;GO:0006511//ubiquitin-dependent protein catabolic process","K12177//COP9 signalosome complex subunit 3","NP_001303286.1//COP9 signalosome complex subunit 3 isoform 6 [Homo sapiens];XP_010635702.1//PREDICTED: COP9 signalosome complex subunit 3 [Fukomys damarensis];NP_003644.2//COP9 signalosome complex subunit 3 isoform 1 [Homo sapiens];NP_001303284.1//COP9 signalosome complex subunit 3 isoform 4 [Homo sapiens];XP_014398312.1//PREDICTED: COP9 signalosome complex subunit 3 isoform X1 [Myotis brandtii]","1//3;3//A2MP1"]
[7693,4940,2.47,2.4,-0.041476635976159,0.89341872259192,"*",0.832064,"ZNF134","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_012509047.1//PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 134-like [Propithecus coquereli]",4]
[137682,2004,7.77,7.55,-0.0414379541952688,0.880812192292089,"*",0.815526,"NDUFAF6","GO:0005634//nucleus;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0005737//cytoplasm","GO:0016740//transferase activity","GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0009058//biosynthetic process","K18163//NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 6","NP_689629.2//NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 isoform 1 precursor [Homo sapiens];XP_022358167.1//NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 isoform X2 [Enhydra lutris kenyoni];NP_001341450.1//NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 isoform 5 [Homo sapiens];XP_020033822.1//NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 isoform X2 [Castor canadensis];NP_001341445.1//NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 isoform 3 [Homo sapiens];NP_001317511.1//NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 isoform 2 [Homo sapiens];XP_018887877.1//PREDICTED: NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 isoform X2 [Gorilla gorilla gorilla]","1//3;3//A2MP1"]
[440574,3755,8.83,8.58,-0.0414357901489203,0.767662375825438,"*",0.66953,"MINOS1","GO:0005739//mitochondrion;GO:0061617//MICOS complex","NA","NA","K17784//mitochondrial inner membrane organizing system protein 1","XP_021798671.1//MICOS complex subunit MIC10-like [Papio anubis];NP_001191012.1//MICOS complex subunit MIC10 isoform c [Homo sapiens]","1//3;3//A2MP1"]
[65056,4410,9.55,9.28,-0.0413759277955391,0.0862128105666575,"*",0.039431,"GPBP1","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0003677//DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated","NA","NP_001317966.1//vasculin isoform 5 [Homo sapiens];NP_001120708.1//vasculin isoform 2 [Homo sapiens];NP_001120707.2//vasculin isoform 3 [Homo sapiens];NP_075064.1//vasculin isoform 1 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[51112,2516,21.62,21.01,-0.0412903610616043,0.724569452630017,"*",0.611398,"TRAPPC12","GO:0005634//nucleus;GO:0005829//cytosol;GO:0000776//kinetochore;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0030008//TRAPP complex","GO:0004175//endopeptidase activity;GO:0017112//Rab guanyl-nucleotide exchange factor activity","GO:0090234//regulation of kinetochore assembly;GO:0051310//metaphase plate congression;GO:1905342//positive regulation of protein localization to kinetochore;GO:0007030//Golgi organization;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0051259//protein oligomerization;GO:0061024//membrane organization","K20309//trafficking protein particle complex subunit 12","NP_057114.5//trafficking protein particle complex subunit 12 [Homo sapiens];XP_018877022.1//PREDICTED: trafficking protein particle complex subunit 12 isoform X1 [Gorilla gorilla gorilla]","1//3;5"]
[4000,2759,187.15,181.87,-0.0412874624814786,0.740743393077425,"*",0.63905,"LMNA","GO:0005652//nuclear lamina;GO:0031012//extracellular matrix;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0005635//nuclear envelope;GO:0016607//nuclear speck;GO:0005882//intermediate filament;GO:0048471//perinuclear region of cytoplasm;GO:0005638//lamin filament;GO:0005829//cytosol","GO:0042802//identical protein binding;GO:0005198//structural molecule activity","GO:0007077//mitotic nuclear envelope disassembly;GO:0071456//cellular response to hypoxia;GO:0055015//ventricular cardiac muscle cell development;GO:1903243//negative regulation of cardiac muscle hypertrophy in response to stress;GO:0090201//negative regulation of release of cytochrome c from mitochondria;GO:0035105//sterol regulatory element binding protein import into nucleus;GO:0030334//regulation of cell migration;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:0036498//IRE1-mediated unfolded protein response;GO:0030951//establishment or maintenance of microtubule cytoskeleton polarity;GO:0032204//regulation of telomere maintenance;GO:0006998//nuclear envelope organization;GO:0008285//negative regulation of cell proliferation;GO:0072201//negative regulation of mesenchymal cell proliferation;GO:0007517//muscle organ development;GO:1900180//regulation of protein localization to nucleus;GO:0007084//mitotic nuclear envelope reassembly;GO:0034613//cellular protein localization;GO:0090343//positive regulation of cell aging;GO:0034504//protein localization to nucleus","K12641//lamin A/C","EAW52998.1//lamin A/C, isoform CRA_c [Homo sapiens];EAW52996.1//lamin A/C, isoform CRA_a [Homo sapiens];NP_001269553.1//lamin isoform E [Homo sapiens];NP_001244303.1//lamin isoform D [Homo sapiens];EAW53000.1//lamin A/C, isoform CRA_d [Homo sapiens]","1//3;3//A2MP1;2//1"]
[22820,3114,38.99,37.89,-0.0412870148889275,0.621021469107934,"*",0.465008,"COPG1","GO:0070382//exocytic vesicle;GO:0030126//COPI vesicle coat;GO:0030133//transport vesicle;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005789//endoplasmic reticulum membrane;GO:0000139//Golgi membrane","GO:0005198//structural molecule activity","GO:0072384//organelle transport along microtubule;GO:0006886//intracellular protein transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0051683//establishment of Golgi localization;GO:0016192//vesicle-mediated transport","K17267//coatomer subunit gamma","NP_057212.1//coatomer subunit gamma-1 [Homo sapiens]","3//A2MP1"]
[100130771,1181,4.97,4.83,-0.041222662726513,0.930015894471696,"*",0.878316,"EFCAB10","NA","GO:0005509//calcium ion binding","NA","K20474//RAD50-interacting protein 1","EAW83369.1//hCG1779729, isoform CRA_b [Homo sapiens];XP_007980695.1//PREDICTED: EF-hand calcium-binding domain-containing protein 10 [Chlorocebus sabaeus];NP_001342459.1//eF-hand calcium-binding domain-containing protein 10 isoform 4 [Homo sapiens]","1//3"]
[8560,2102,61.2,59.49,-0.0408844746300101,0.612294634531407,"*",0.456442,"DEGS1","GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0005887//integral component of plasma membrane;GO:0035579//specific granule membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005739//mitochondrion;GO:0005886//plasma membrane","GO:0042284//sphingolipid delta-4 desaturase activity;GO:0009055//electron transfer activity","GO:0006636//unsaturated fatty acid biosynthetic process;GO:0030148//sphingolipid biosynthetic process;GO:0043312//neutrophil degranulation;GO:0006633//fatty acid biosynthetic process;GO:0046513//ceramide biosynthetic process","K04712//sphingolipid 4-desaturase/C4-monooxygenase [EC:1.14.19.17 1.14.18.5]","NP_001308470.1//sphingolipid delta(4)-desaturase DES1 isoform 2 [Homo sapiens];NP_003667.1//sphingolipid delta(4)-desaturase DES1 isoform 1 [Homo sapiens];XP_017804685.1//sphingolipid delta(4)-desaturase DES1 isoform X1 [Papio anubis]","1//3;3//A2MP1"]
[10213,1734,48.76,47.4,-0.0408110668345906,0.671306196686427,"*",0.552964,"PSMD14","GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0008541//proteasome regulatory particle, lid subcomplex;GO:0000502//proteasome complex;GO:0022624//proteasome accessory complex;GO:0031597//cytosolic proteasome complex;GO:0005829//cytosol;GO:0005576//extracellular region;GO:1904813//ficolin-1-rich granule lumen","GO:0004175//endopeptidase activity;GO:0061578//Lys63-specific deubiquitinase activity;GO:0046872//metal ion binding;GO:0008237//metallopeptidase activity;GO:0061133//endopeptidase activator activity;GO:0036459//thiol-dependent ubiquitinyl hydrolase activity;GO:0070628//proteasome binding","GO:0043687//post-translational protein modification;GO:0038061//NIK/NF-kappaB signaling;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0006521//regulation of cellular amino acid metabolic process;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle;GO:0045471//response to ethanol;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0016579//protein deubiquitination;GO:0043312//neutrophil degranulation;GO:0043488//regulation of mRNA stability;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0000209//protein polyubiquitination;GO:0070536//protein K63-linked deubiquitination;GO:0055085//transmembrane transport;GO:0000165//MAPK cascade;GO:0050852//T cell receptor signaling pathway;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0061136//regulation of proteasomal protein catabolic process;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:1902036//regulation of hematopoietic stem cell differentiation;GO:0000724//double-strand break repair via homologous recombination;GO:0006303//double-strand break repair via nonhomologous end joining","K03030//26S proteasome regulatory subunit N11","XP_020860546.1//26S proteasome non-ATPase regulatory subunit 14 isoform X1 [Phascolarctos cinereus]",5]
[23231,4438,11.49,11.17,-0.0407496121627985,0.628961786431965,"*",0.505524,"SEL1L3","GO:0016021//integral component of membrane","NA","NA","K11653//AT-rich interactive domain-containing protein 1;K05746//enabled;K14026//SEL1 protein;K12891//splicing factor, arginine/serine-rich 2;K07432//beta-1,4-N-acetylglucosaminyltransferase [EC:2.4.1.141]","NP_001284521.1//protein sel-1 homolog 3 isoform 2 [Homo sapiens];XP_016806909.1//PREDICTED: protein sel-1 homolog 3 isoform X1 [Pan troglodytes];NP_056002.2//protein sel-1 homolog 3 isoform 1 [Homo sapiens]","4;1//3"]
[112939,4518,53.89,52.39,-0.0407261247206872,0.459069781160093,"*",0.309658,"NACC1","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0030054//cell junction;GO:0005737//cytoplasm","NA","GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0051260//protein homooligomerization;GO:0008284//positive regulation of cell proliferation","K10486//BTB/POZ domain-containing protein 14","XP_002828800.2//PREDICTED: nucleus accumbens-associated protein 1 [Pongo abelii]","3//A2MP1"]
[976,3290,18.33,17.82,-0.0407094490179636,0.706753087674714,"*",0.59194,"ADGRE5","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0030667//secretory granule membrane;GO:0005887//integral component of plasma membrane;GO:0005925//focal adhesion;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0005509//calcium ion binding;GO:0004888//transmembrane signaling receptor activity;GO:0004930//G-protein coupled receptor activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0007166//cell surface receptor signaling pathway;GO:0006954//inflammatory response;GO:0007155//cell adhesion;GO:0006928//movement of cell or subcellular component;GO:0006955//immune response;GO:0043312//neutrophil degranulation","K08446//CD97 antigen","XP_011949537.1//PREDICTED: CD97 antigen isoform X1 [Cercocebus atys];XP_011949539.1//PREDICTED: CD97 antigen isoform X3 [Cercocebus atys];XP_011949542.1//PREDICTED: CD97 antigen isoform X5 [Cercocebus atys]","4;3//A2MP1;2//1"]
[651,5828,0.36,0.35,-0.0406419844973459,1.02139508404604,"*",0.994348,"BMP3","GO:0070062//extracellular exosome;GO:0005615//extracellular space","GO:0008083//growth factor activity;GO:0005125//cytokine activity;GO:0005102//receptor binding;GO:0005160//transforming growth factor beta receptor binding;GO:0070700//BMP receptor binding","GO:0001649//osteoblast differentiation;GO:0007267//cell-cell signaling;GO:0043408//regulation of MAPK cascade;GO:0051216//cartilage development;GO:0030509//BMP signaling pathway;GO:0060395//SMAD protein signal transduction;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0001501//skeletal system development;GO:0048468//cell development;GO:0042981//regulation of apoptotic process","K05496//bone morphogenetic protein 3/3B","NP_001192.3//bone morphogenetic protein 3 preproprotein [Homo sapiens]","3//A2MP1"]
[11146,2041,2.52,2.45,-0.0406419844973458,0.921532977198697,"*",0.867824,"GLMN","GO:0031462//Cul2-RING ubiquitin ligase complex;GO:0031464//Cul4A-RING E3 ubiquitin ligase complex;GO:0005622//intracellular;GO:0005737//cytoplasm;GO:0031463//Cul3-RING ubiquitin ligase complex;GO:0031461//cullin-RING ubiquitin ligase complex","GO:0055105//ubiquitin-protein transferase inhibitor activity;GO:0005171//hepatocyte growth factor receptor binding;GO:0031625//ubiquitin protein ligase binding","GO:0032434//regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0040029//regulation of gene expression, epigenetic;GO:0045086//positive regulation of interleukin-2 biosynthetic process;GO:0042692//muscle cell differentiation;GO:0042130//negative regulation of T cell proliferation;GO:0042327//positive regulation of phosphorylation;GO:0001843//neural tube closure;GO:0050715//positive regulation of cytokine secretion;GO:0001570//vasculogenesis","K18587//ubiquinone biosynthesis protein COQ9","XP_016855626.1//PREDICTED: glomulin isoform X1 [Homo sapiens];XP_016855627.1//PREDICTED: glomulin isoform X2 [Homo sapiens]","1//3;2//1"]
[51324,1708,107.8,104.82,-0.0404431640019522,0.231216431480858,"*",0.1289248,"SPG21","GO:0043231//intracellular membrane-bounded organelle;GO:0010008//endosome membrane;GO:0030140//trans-Golgi network transport vesicle;GO:0005829//cytosol","GO:0042609//CD4 receptor binding","GO:0050851//antigen receptor-mediated signaling pathway","K19367//maspardin","NP_057714.1//maspardin isoform a [Homo sapiens];XP_014997952.1//PREDICTED: maspardin isoform X1 [Macaca mulatta]","6;4"]
[6687,3050,22.46,21.84,-0.0403850714807488,0.702528266866342,"*",0.587346,"SPG7","GO:0005757//mitochondrial permeability transition pore complex;GO:1904115//axon cytoplasm;GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0005745//m-AAA complex","GO:0008233//peptidase activity;GO:0004222//metalloendopeptidase activity;GO:0005524//ATP binding;GO:0051082//unfolded protein binding;GO:0008270//zinc ion binding","GO:0007399//nervous system development;GO:0006851//mitochondrial calcium ion transmembrane transport;GO:0006508//proteolysis;GO:0046902//regulation of mitochondrial membrane permeability;GO:0008089//anterograde axonal transport;GO:1902686//mitochondrial outer membrane permeabilization involved in programmed cell death","K09552//spastic paraplegia 7 [EC:3.4.24.-]","NP_003110.1//paraplegin isoform 1 precursor [Homo sapiens];NP_955399.1//paraplegin isoform 2 precursor [Homo sapiens]","3//A2MP1;2//1"]
[3615,1712,112.23,109.14,-0.04027842289934,0.531723079334331,"*",0.378038,"IMPDH2","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0000166//nucleotide binding;GO:0003938//IMP dehydrogenase activity","GO:0006177//GMP biosynthetic process","K00088//IMP dehydrogenase [EC:1.1.1.205]","XP_020651049.1//inosine-5'-monophosphate dehydrogenase 2 isoform X2 [Pogona vitticeps]","2//1"]
[57035,1525,4,3.89,-0.0402298447885327,0.78841663866497,"*",0.697996,"RSRP1","NA","NA","NA","K15176//RNA polymerase-associated protein CTR9;K15174//RNA polymerase II-associated factor 1","NP_064713.3//arginine/serine-rich protein 1 [Homo sapiens];BAX25201.1//arginine/serine-rich protein 1 [Pan troglodytes]","4;1//3"]
[8772,1855,27.28,26.53,-0.0402189687954766,0.754397758232236,"*",0.653994,"FADD","NA","NA","NA","K02373//FAS-associated death domain protein","XP_011896682.1//PREDICTED: FAS-associated death domain protein [Cercocebus atys]","3//A2MP1"]
[51187,1487,73.85,71.82,-0.0402122679874935,0.628424935230542,"*",0.505958,"RSL24D1","GO:0005840//ribosome;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0022625//cytosolic large ribosomal subunit","GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome","GO:0042254//ribosome biogenesis;GO:1902626//assembly of large subunit precursor of preribosome;GO:0006412//translation;GO:0000027//ribosomal large subunit assembly","K02896//large subunit ribosomal protein L24e","XP_019824362.1//PREDICTED: probable ribosome biogenesis protein RLP24 [Bos indicus]","2//1"]
[493856,5892,10.92,10.62,-0.0401890901156989,0.723278155558854,"*",0.610082,"CISD2","NA","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K16603//tubulin polyglutamylase TTLL9 [EC:6.-.-.-];K04460//serine/threonine-protein phosphatase 5 [EC:3.1.3.16]","XP_003257613.1//PREDICTED: CDGSH iron-sulfur domain-containing protein 2 [Nomascus leucogenys]",4]
[54475,2627,12.49,12.15,-0.0398171631148141,0.785370042637581,"*",0.694168,"NLE1","GO:0005840//ribosome;GO:0005634//nucleus;GO:0005730//nucleolus","NA","GO:0045930//negative regulation of mitotic cell cycle;GO:0001822//kidney development;GO:0000027//ribosomal large subunit assembly;GO:2001268//negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0001826//inner cell mass cell differentiation;GO:0061484//hematopoietic stem cell homeostasis;GO:0001756//somitogenesis;GO:0007219//Notch signaling pathway;GO:0048705//skeletal system morphogenesis","K14855//ribosome assembly protein 4","XP_017746378.1//PREDICTED: notchless protein homolog 1 isoform X1 [Rhinopithecus bieti];EAW80167.1//notchless homolog 1 (Drosophila), isoform CRA_c, partial [Homo sapiens]","4;2//1"]
[54470,1796,21.68,21.09,-0.0398056615601801,0.640597473716712,"*",0.519528,"ARMCX6","GO:0016021//integral component of membrane;GO:0005741//mitochondrial outer membrane","NA","NA","NA","XP_011529278.1//PREDICTED: protein ARMCX6 isoform X1 [Homo sapiens]","1//3;3//A2MP1"]
[10139,2504,9.57,9.31,-0.0397377569272318,0.911952547904991,"*",0.855662,"ARFRP1","GO:0016020//membrane;GO:0032588//trans-Golgi network membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005802//trans-Golgi network","GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0007369//gastrulation;GO:0007165//signal transduction;GO:0034067//protein localization to Golgi apparatus;GO:0043001//Golgi to plasma membrane protein transport;GO:0007264//small GTPase mediated signal transduction;GO:0042147//retrograde transport, endosome to Golgi","K07952//ADP-ribosylation factor related protein 1","XP_008008901.1//PREDICTED: ADP-ribosylation factor-related protein 1 isoform X1 [Chlorocebus sabaeus];EAW75230.1//ADP-ribosylation factor related protein 1, isoform CRA_a [Homo sapiens];XP_009435924.1//PREDICTED: ADP-ribosylation factor-related protein 1 isoform X1 [Pan troglodytes];XP_020016627.1//ADP-ribosylation factor-related protein 1 isoform X1 [Castor canadensis];NP_003215.1//ADP-ribosylation factor-related protein 1 isoform a [Homo sapiens];XP_017827664.1//PREDICTED: ADP-ribosylation factor-related protein 1 isoform X4 [Callithrix jacchus]","3//A2MP1;2//1;5"]
[51097,2482,22.86,22.24,-0.0396686154909709,0.739310349473684,"*",0.637536,"SCCPDH","NA","NA","NA","K17581//consortin;K13171//serine/arginine repetitive matrix protein 1;K02184//formin 2","XP_011727835.1//PREDICTED: saccharopine dehydrogenase-like oxidoreductase [Macaca nemestrina]","2//1"]
[399979,5028,6.64,6.46,-0.0396490766529999,0.093694700243309,"*",0.0433926,"SNX19","GO:0031901//early endosome membrane;GO:0005737//cytoplasm;GO:0030659//cytoplasmic vesicle membrane","GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0035091//phosphatidylinositol binding","GO:0002062//chondrocyte differentiation;GO:1990502//dense core granule maturation;GO:0030073//insulin secretion;GO:0006887//exocytosis","K17930//sorting nexin-19","NP_001334854.1//sorting nexin-19 isoform 10 [Homo sapiens];NP_055573.2//sorting nexin-19 isoform 1 [Homo sapiens];XP_011825428.1//PREDICTED: sorting nexin-19 isoform X3 [Mandrillus leucophaeus];NP_001334847.1//sorting nexin-19 isoform 3 [Homo sapiens];NP_001334850.1//sorting nexin-19 isoform 6 [Homo sapiens];NP_001334851.1//sorting nexin-19 isoform 7 [Homo sapiens];NP_001334848.1//sorting nexin-19 isoform 4 [Homo sapiens];NP_001334852.1//sorting nexin-19 isoform 8 [Homo sapiens];NP_001334849.1//sorting nexin-19 isoform 5 [Homo sapiens]","1//3;2//1"]
[3065,2091,42.53,41.38,-0.0395472097657541,0.669586449395483,"*",0.551254,"HDAC1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000785//chromatin;GO:0016580//Sin3 complex;GO:0000790//nuclear chromatin;GO:0005737//cytoplasm;GO:0016581//NuRD complex;GO:0043234//protein complex;GO:0005829//cytosol;GO:0000118//histone deacetylase complex","GO:0047485//protein N-terminus binding;GO:0001103//RNA polymerase II repressing transcription factor binding;GO:0032041//NAD-dependent histone deacetylase activity (H3-K14 specific);GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0033613//activating transcription factor binding;GO:0001047//core promoter binding;GO:0004407//histone deacetylase activity;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0001046//core promoter sequence-specific DNA binding;GO:0042826//histone deacetylase binding;GO:0002039//p53 binding;GO:0033558//protein deacetylase activity;GO:0070491//repressing transcription factor binding;GO:0044212//transcription regulatory region DNA binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0001106//RNA polymerase II transcription corepressor activity;GO:0046872//metal ion binding;GO:0051059//NF-kappaB binding;GO:0019213//deacetylase activity;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0008134//transcription factor binding;GO:0019899//enzyme binding;GO:0031492//nucleosomal DNA binding","GO:0006338//chromatin remodeling;GO:0007596//blood coagulation;GO:0061198//fungiform papilla formation;GO:0060789//hair follicle placode formation;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0060766//negative regulation of androgen receptor signaling pathway;GO:0043922//negative regulation by host of viral transcription;GO:0045892//negative regulation of transcription, DNA-templated;GO:0009913//epidermal cell differentiation;GO:0070933//histone H4 deacetylation;GO:0043066//negative regulation of apoptotic process;GO:0016032//viral process;GO:0042475//odontogenesis of dentin-containing tooth;GO:1901796//regulation of signal transduction by p53 class mediator;GO:1904837//beta-catenin-TCF complex assembly;GO:0006346//methylation-dependent chromatin silencing;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0010870//positive regulation of receptor biosynthetic process;GO:0016575//histone deacetylation;GO:0006476//protein deacetylation;GO:0006355//regulation of transcription, DNA-templated;GO:0010629//negative regulation of gene expression;GO:0042733//embryonic digit morphogenesis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0043044//ATP-dependent chromatin remodeling;GO:0032922//circadian regulation of gene expression;GO:0061029//eyelid development in camera-type eye;GO:0006351//transcription, DNA-templated;GO:0045652//regulation of megakaryocyte differentiation;GO:0006325//chromatin organization;GO:0070932//histone H3 deacetylation;GO:0008284//positive regulation of cell proliferation","K06067//histone deacetylase 1/2 [EC:3.5.1.98]","NP_004955.2//histone deacetylase 1 [Homo sapiens]","2//1"]
[3183,3226,256.41,249.48,-0.0395283641866377,0.141312864294663,"*",0.0706122,"HNRNPC","GO:0030529//intracellular ribonucleoprotein complex;GO:0019013//viral nucleocapsid","GO:0003723//RNA binding","NA","K12884//heterogeneous nuclear ribonucleoprotein C1/C2","BAD92764.1//Heterogeneous nuclear ribonucleoproteins C1/C2 variant, partial [Homo sapiens];XP_863431.2//heterogeneous nuclear ribonucleoproteins C1/C2 isoform X4 [Canis lupus familiaris]","1//3;3//A2MP1;2//1"]
[440138,2595,1.11,1.08,-0.0395283641866375,1.02186902021893,"*",0.993466,"ALG11","GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0004377//GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity","GO:0006490//oligosaccharide-lipid intermediate biosynthetic process;GO:0033577//protein glycosylation in endoplasmic reticulum","K03844//alpha-1,2-mannosyltransferase [EC:2.4.1.131]","NP_001004127.2//GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase [Homo sapiens]","2//1"]
[144453,2258,0.74,0.72,-0.0395283641866375,0.833926641436464,"*",0.755932,"BEST3","GO:0034707//chloride channel complex;GO:0005886//plasma membrane","GO:0005254//chloride channel activity","GO:0043271//negative regulation of ion transport","K13880//bestrophin-3","NP_116124.2//bestrophin-3 isoform 1 [Homo sapiens];NP_001269543.1//bestrophin-3 isoform 4 [Homo sapiens];NP_689652.2//bestrophin-3 isoform 2 [Homo sapiens];XP_016874354.1//PREDICTED: bestrophin-3 isoform X5 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[26354,2013,48.91,47.59,-0.0394710101772974,0.6536895752552,"*",0.533174,"GNL3","GO:0016020//membrane;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0005730//nucleolus;GO:0016604//nuclear body","GO:0003723//RNA binding;GO:0048027//mRNA 5'-UTR binding;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:1902895//positive regulation of pri-miRNA transcription from RNA polymerase II promoter;GO:0042127//regulation of cell proliferation;GO:0033235//positive regulation of protein sumoylation;GO:0032206//positive regulation of telomere maintenance;GO:0042254//ribosome biogenesis;GO:0008283//cell proliferation;GO:0019827//stem cell population maintenance;GO:0017145//stem cell division;GO:1904816//positive regulation of protein localization to chromosome, telomeric region","K14538//nuclear GTP-binding protein","EAW65249.1//guanine nucleotide binding protein-like 3 (nucleolar), isoform CRA_a [Homo sapiens];NP_055181.3//guanine nucleotide-binding protein-like 3 isoform 1 [Homo sapiens]","1//3;4"]
[100129361,4840,5.56,5.41,-0.0394562888966923,0.827516971998891,"*",0.747428,"SMIM10L1","NA","NA","NA","NA","DAA29354.1//TPA: hypothetical protein BOS_5846 [Bos taurus]","1//3"]
[84950,2780,7.43,7.23,-0.0393665635874783,0.847622086539121,"*",0.773812,"PRPF38A","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0005681//spliceosomal complex;GO:0071011//precatalytic spliceosome","GO:0003723//RNA binding","GO:0006397//mRNA processing;GO:0000398//mRNA splicing, via spliceosome;GO:0008380//RNA splicing","K12849//pre-mRNA-splicing factor 38A","NP_116253.2//pre-mRNA-splicing factor 38A [Homo sapiens]","3//A2MP1"]
[9654,4997,11.16,10.86,-0.0393129240248262,0.737803256806796,"*",0.636144,"TTLL4","GO:0005929//cilium;GO:0005874//microtubule;GO:0005829//cytosol","GO:0015631//tubulin binding;GO:0070739//protein-glutamic acid ligase activity;GO:0070740//tubulin-glutamic acid ligase activity;GO:0005524//ATP binding","GO:0018200//peptidyl-glutamic acid modification;GO:0018095//protein polyglutamylation","K16601//tubulin polyglutamylase TTLL4 [EC:6.-.-.-]","NP_055455.3//tubulin polyglutamylase TTLL4 [Homo sapiens]",4]
[8614,5361,20.46,19.91,-0.0393129240248262,0.632936509485095,"*",0.51173,"STC2","GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005576//extracellular region;GO:0048471//perinuclear region of cytoplasm","GO:0020037//heme binding;GO:0042803//protein homodimerization activity;GO:0019899//enzyme binding;GO:0005179//hormone activity","GO:0043687//post-translational protein modification;GO:0071456//cellular response to hypoxia;GO:0046697//decidualization;GO:0046885//regulation of hormone biosynthetic process;GO:0043434//response to peptide hormone;GO:0010629//negative regulation of gene expression;GO:0033280//response to vitamin D;GO:0007566//embryo implantation;GO:0006979//response to oxidative stress;GO:0044267//cellular protein metabolic process;GO:2001256//regulation of store-operated calcium entry;GO:0040015//negative regulation of multicellular organism growth;GO:0006874//cellular calcium ion homeostasis;GO:0030968//endoplasmic reticulum unfolded protein response","NA","NP_003705.1//stanniocalcin-2 precursor [Homo sapiens]","2//1"]
[84680,2196,6.71,6.53,-0.0392297746537527,0.874138670822605,"*",0.807596,"ACCS","NA","GO:0042802//identical protein binding;GO:0003824//catalytic activity;GO:0030170//pyridoxal phosphate binding;GO:0042803//protein homodimerization activity","GO:0009058//biosynthetic process","K00816//kynurenine---oxoglutarate transaminase / cysteine-S-conjugate beta-lyase / glutamine---phenylpyruvate transaminase [EC:2.6.1.7 4.4.1.13 2.6.1.64];K00815//tyrosine aminotransferase [EC:2.6.1.5];K00814//alanine transaminase [EC:2.6.1.2]","XP_005253227.2//PREDICTED: 1-aminocyclopropane-1-carboxylate synthase-like protein 1 isoform X1 [Homo sapiens]","1//3;3//A2MP1"]
[3336,965,228.54,222.43,-0.0390953106539907,0.520377616595136,"*",0.364336,"HSPE1","NA","NA","NA","K04078//chaperonin GroES","XP_019694695.1//PREDICTED: 10 kDa heat shock protein, mitochondrial [Felis catus]","2//1"]
[64780,3478,5.62,5.47,-0.0390292974283697,0.765510877782565,"*",0.667366,"MICAL1","GO:0005829//cytosol;GO:0005882//intermediate filament;GO:1990026//hippocampal mossy fiber expansion;GO:0005737//cytoplasm;GO:0030496//midbody","GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen;GO:0019901//protein kinase binding;GO:0003779//actin binding;GO:0046872//metal ion binding;GO:0004497//monooxygenase activity;GO:0017124//SH3 domain binding;GO:0017137//Rab GTPase binding;GO:0071949//FAD binding","GO:0019417//sulfur oxidation;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007165//signal transduction;GO:0007596//blood coagulation;GO:0055114//oxidation-reduction process;GO:0001933//negative regulation of protein phosphorylation;GO:0007010//cytoskeleton organization;GO:1903305//regulation of regulated secretory pathway;GO:0030042//actin filament depolymerization","K19947//F-actin monooxygenase [EC:1.14.13.225]","NP_001273542.1//[F-actin]-methionine sulfoxide oxidase MICAL1 isoform 3 [Homo sapiens];NP_001152763.1//[F-actin]-methionine sulfoxide oxidase MICAL1 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[116028,1451,23.24,22.62,-0.0390111394147082,0.809682054904163,"*",0.721942,"RMI2","GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck","GO:0003677//DNA binding","GO:1901796//regulation of signal transduction by p53 class mediator;GO:0000732//strand displacement;GO:0033045//regulation of sister chromatid segregation;GO:0000731//DNA synthesis involved in DNA repair;GO:0006260//DNA replication","K15365//RecQ-mediated genome instability protein 2","NP_689521.1//recQ-mediated genome instability protein 2 [Homo sapiens]","2//1"]
[26528,2221,113.43,110.41,-0.038931410062299,0.487274680273349,"*",0.334784,"DAZAP1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:1990904//ribonucleoprotein complex;GO:0043234//protein complex;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0035613//RNA stem-loop binding;GO:0008266//poly(U) RNA binding;GO:0034046//poly(G) binding","GO:0048026//positive regulation of mRNA splicing, via spliceosome;GO:0008283//cell proliferation;GO:0030154//cell differentiation;GO:0007283//spermatogenesis;GO:0001893//maternal placenta development","K14411//RNA-binding protein Musashi","NP_001338962.1//DAZ-associated protein 1 isoform c [Homo sapiens];NP_001338964.1//DAZ-associated protein 1 isoform e [Homo sapiens];NP_061832.2//DAZ-associated protein 1 isoform b [Homo sapiens];XP_014322693.1//PREDICTED: DAZ-associated protein 1 isoform X3 [Myotis lucifugus];NP_733829.1//DAZ-associated protein 1 isoform a [Homo sapiens]","1//3;3//A2MP1;2//1"]
[9812,4627,14.7,14.31,-0.0387924829970588,0.655438932330827,"*",0.534806,"KIAA0141","GO:0005739//mitochondrion","NA","GO:0043281//regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors","K14026//SEL1 protein","NP_055588.3//death ligand signal enhancer precursor [Homo sapiens]","4;2//1"]
[144404,7510,22.26,21.67,-0.0387544392482859,0.578549186507596,"*",0.421978,"TMEM120B","GO:0005637//nuclear inner membrane;GO:0016021//integral component of membrane","NA","GO:0051291//protein heterooligomerization;GO:0045444//fat cell differentiation","K14574//ribosome maturation protein SDO1;K12025//tripartite motif-containing protein 52","NP_001074294.2//transmembrane protein 120B [Homo sapiens]","2//1"]
[6727,1140,102.7,99.98,-0.0387247495220344,0.651955662710188,"*",0.49515,"SRP14","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005786//signal recognition particle, endoplasmic reticulum targeting","GO:0050825//ice binding;GO:0030942//endoplasmic reticulum signal peptide binding;GO:0008312//7S RNA binding","GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0042493//response to drug","K03104//signal recognition particle subunit SRP14","NP_001125409.1//signal recognition particle 14 kDa protein [Pongo abelii];NP_001296363.1//signal recognition particle 14 kDa protein isoform 2 [Homo sapiens]","1//3;5"]
[51493,2081,32.18,31.33,-0.0386195563523926,0.728306462769504,"*",0.615372,"RTCB","GO:0043231//intracellular membrane-bounded organelle;GO:0072669//tRNA-splicing ligase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005789//endoplasmic reticulum membrane","GO:0003723//RNA binding;GO:0046872//metal ion binding;GO:0005524//ATP binding;GO:0017166//vinculin binding;GO:0003972//RNA ligase (ATP) activity","GO:0006388//tRNA splicing, via endonucleolytic cleavage and ligation","K14415//tRNA-splicing ligase RtcB [EC:6.5.1.3]","EPY77446.1//tRNA-splicing ligase RtcB-like protein [Camelus ferus]",4]
[399909,6584,25.38,24.71,-0.0385970585123215,0.578844064959615,"*",0.421722,"PCNX3","GO:0016021//integral component of membrane","NA","NA","K22016//mucin-3/17","NP_115599.2//pecanex-like protein 3 [Homo sapiens]","3//A2MP1"]
[63943,1357,4.55,4.43,-0.0385598465310403,0.931363773714891,"*",0.880172,"FKBPL","GO:0005829//cytosol","NA","GO:0009314//response to radiation;GO:0050821//protein stabilization","K20097//FK506-binding protein-like","XP_007971213.1//PREDICTED: FK506-binding protein-like isoform X1 [Chlorocebus sabaeus]","3//A2MP1"]
[79037,1587,15.58,15.17,-0.0384741478146357,0.839139170097061,"*",0.763126,"PVRIG","GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0004872//receptor activity;GO:0019902//phosphatase binding","GO:0050860//negative regulation of T cell receptor signaling pathway","K13055//cohesin complex subunit SA-3","NP_076975.2//transmembrane protein PVRIG [Homo sapiens]","3//A2MP1"]
[55379,2933,120.95,117.78,-0.0383161906799601,0.391133778772254,"*",0.251688,"LRRC59","NA","NA","NA","K19613//leucine-rich repeat protein SHOC2","XP_017827410.1//PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein LOC100387424 [Callithrix jacchus]","3//A2MP1"]
[4595,1821,7.25,7.06,-0.0383128116311165,0.795906436781609,"*",0.70657,"MUTYH","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion","GO:0032407//MutSalpha complex binding;GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0016787//hydrolase activity;GO:0019104//DNA N-glycosylase activity;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0000701//purine-specific mismatch base pair DNA N-glycosylase activity","GO:0045007//depurination;GO:0006284//base-excision repair;GO:0006281//DNA repair;GO:0006298//mismatch repair","K03575//A/G-specific adenine glycosylase [EC:3.2.2.-]","NP_001337579.1//adenine DNA glycosylase isoform 9 [Homo sapiens];NP_001121897.1//adenine DNA glycosylase isoform 5 [Homo sapiens];NP_036354.1//adenine DNA glycosylase isoform 1 [Homo sapiens];NP_001041638.1//adenine DNA glycosylase isoform 4 [Homo sapiens];NP_001041636.1//adenine DNA glycosylase isoform 2 [Homo sapiens];XP_018873066.1//PREDICTED: adenine DNA glycosylase isoform X8 [Gorilla gorilla gorilla];NP_001280119.1//adenine DNA glycosylase isoform 6 [Homo sapiens]","1//3;2//1"]
[573,3885,13.37,13.02,-0.0382700169277173,0.760521104967603,"*",0.661302,"BAG1","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0005057//signal transducer activity, downstream of receptor;GO:0051087//chaperone binding;GO:0000774//adenyl-nucleotide exchange factor activity","GO:1900034//regulation of cellular response to heat;GO:0043066//negative regulation of apoptotic process;GO:0007166//cell surface receptor signaling pathway;GO:0006915//apoptotic process","K09555//BCL2-associated athanogene 1","BAD96469.1//BCL2-associated athanogene isoform 1L variant, partial [Homo sapiens]","1//3;5"]
[1627,2942,49.32,48.03,-0.0382369911654259,0.634676039521754,"*",0.47853,"DBN1","GO:0030425//dendrite;GO:0005921//gap junction;GO:0005622//intracellular;GO:0005737//cytoplasm;GO:0030863//cortical cytoskeleton;GO:0030426//growth cone;GO:0015629//actin cytoskeleton;GO:0042641//actomyosin;GO:0005886//plasma membrane","GO:0003779//actin binding;GO:0005522//profilin binding;GO:0045296//cadherin binding","GO:0050773//regulation of dendrite development;GO:0061351//neural precursor cell proliferation;GO:0010644//cell communication by electrical coupling;GO:0007015//actin filament organization;GO:0048168//regulation of neuronal synaptic plasticity;GO:0032507//maintenance of protein location in cell;GO:0010643//cell communication by chemical coupling","K20520//drebrin-like protein","NP_004386.2//drebrin isoform a [Homo sapiens];NP_543157.1//drebrin isoform b [Homo sapiens]","3//A2MP1;2//1"]
[57062,2967,50.59,49.27,-0.0381427674950869,0.612603972800537,"*",0.456826,"DDX24","GO:0016020//membrane;GO:0005730//nucleolus;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0004004//ATP-dependent RNA helicase activity;GO:0005524//ATP binding;GO:0003724//RNA helicase activity;GO:0004386//helicase activity","GO:0016070//RNA metabolic process;GO:0010501//RNA secondary structure unwinding","K14805//ATP-dependent RNA helicase DDX24/MAK5 [EC:3.6.4.13]","NP_065147.1//ATP-dependent RNA helicase DDX24 [Homo sapiens]","3//A2MP1"]
[114987,4868,3.86,3.76,-0.037868185590443,0.866435580178098,"*",0.79793,"WDR31","NA","NA","NA","K12025//tripartite motif-containing protein 52","NP_660284.1//WD repeat-containing protein 31 isoform 3 [Homo sapiens];NP_001012361.1//WD repeat-containing protein 31 isoform 1 [Homo sapiens];XP_015981769.1//PREDICTED: WD repeat-containing protein 31 isoform X3 [Rousettus aegyptiacus]","4;3//A2MP1;2//1"]
[91869,5112,9.67,9.42,-0.0377888298640581,0.753278589323124,"*",0.652788,"RFT1","GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0005319//lipid transporter activity","GO:0034203//glycolipid translocation;GO:0008643//carbohydrate transport","K06316//oligosaccharide translocation protein RFT1","NP_443091.1//protein RFT1 homolog [Homo sapiens]","3//A2MP1"]
[54537,3598,12,11.69,-0.0377594759642246,0.626287916101364,"*",0.502826,"FAM35A","NA","NA","NA","NA","NP_001317041.1//protein FAM35A isoform 1 [Homo sapiens];NP_061927.2//protein FAM35A isoform 2 [Homo sapiens]","1//3;2//1"]
[165631,4180,15.49,15.09,-0.0377443382628853,0.747173877090119,"*",0.646188,"PARP15","GO:0005634//nucleus","GO:0070403//NAD+ binding;GO:0001191//transcriptional repressor activity, RNA polymerase II transcription factor binding;GO:0003950//NAD+ ADP-ribosyltransferase activity","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0070212//protein poly-ADP-ribosylation","K15261//poly [ADP-ribose] polymerase 10/14/15 [EC:2.4.2.30]","NP_001295250.1//poly [ADP-ribose] polymerase 15 isoform 4 precursor [Homo sapiens];NP_001106995.1//poly [ADP-ribose] polymerase 15 isoform 1 [Homo sapiens];NP_001295249.1//poly [ADP-ribose] polymerase 15 isoform 3 [Homo sapiens];NP_689828.1//poly [ADP-ribose] polymerase 15 isoform 2 precursor [Homo sapiens]","1//3;2//1"]
[339210,2074,1.55,1.51,-0.0377196659491588,0.959468490217889,"*",0.917964,"C17orf67","GO:0005576//extracellular region","NA","NA","NA","Q0P5P2.2//RecName: Full=Uncharacterized protein C17orf67; Flags: Precursor","3//A2MP1"]
[10541,1617,176.42,171.89,-0.0375285065280672,0.469217121223287,"*",0.318882,"ANP32B","NA","NA","NA","K18647//acidic leucine-rich nuclear phosphoprotein 32 family member B","XP_016376038.1//PREDICTED: acidic leucine-rich nuclear phosphoprotein 32 family member B isoform X1 [Sinocyclocheilus rhinocerous]","2//1"]
[643699,5329,0.39,0.38,-0.0374747054186629,0.942578633805601,"*",0.895432,"GOLGA8N","GO:0005794//Golgi apparatus","NA","NA","K20358//golgin subfamily A member 2","NP_001269423.1//golgin subfamily A member 8N [Homo sapiens]","1//3"]
[245711,1756,2.73,2.66,-0.0374747054186627,0.972969763939552,"*",0.935084,"SPDYA","GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0019901//protein kinase binding","GO:0007140//male meiotic nuclear division;GO:0007275//multicellular organism development;GO:0000082//G1/S transition of mitotic cell cycle;GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0006974//cellular response to DNA damage stimulus;GO:0008284//positive regulation of cell proliferation","K08694//speedy","NP_877433.2//speedy protein A isoform 1 [Homo sapiens];NP_001008779.1//speedy protein A isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[4522,3466,64.22,62.58,-0.037321006484848,0.531114400140895,"*",0.377572,"MTHFD1","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005739//mitochondrion","GO:0004488//methylenetetrahydrofolate dehydrogenase (NADP+) activity;GO:0016787//hydrolase activity;GO:0005524//ATP binding;GO:0004329//formate-tetrahydrofolate ligase activity;GO:0004487//methylenetetrahydrofolate dehydrogenase (NAD+) activity","GO:0019346//transsulfuration;GO:0061053//somite development;GO:0007507//heart development;GO:0001780//neutrophil homeostasis;GO:0006164//purine nucleotide biosynthetic process;GO:0035999//tetrahydrofolate interconversion;GO:0009257//10-formyltetrahydrofolate biosynthetic process;GO:0001843//neural tube closure;GO:0009070//serine family amino acid biosynthetic process;GO:0009086//methionine biosynthetic process","K00288//methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3]","XP_016781707.1//PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Pan troglodytes]","3//A2MP1"]
[64326,2695,9.01,8.78,-0.0373061662781805,0.700040860782257,"*",0.584872,"COP1","GO:0005654//nucleoplasm;GO:0031464//Cul4A-RING E3 ubiquitin ligase complex;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0000139//Golgi membrane","GO:0061630//ubiquitin protein ligase activity;GO:0046872//metal ion binding;GO:0004842//ubiquitin-protein transferase activity","GO:0043687//post-translational protein modification;GO:0010212//response to ionizing radiation;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process","K10143//E3 ubiquitin-protein ligase RFWD2 [EC:2.3.2.27]","NP_001001740.1//E3 ubiquitin-protein ligase RFWD2 isoform b [Homo sapiens];NP_071902.2//E3 ubiquitin-protein ligase RFWD2 isoform a [Homo sapiens];NP_001273573.1//E3 ubiquitin-protein ligase RFWD2 isoform c precursor [Homo sapiens]","6;1//3;3//A2MP1"]
[7485,1485,13.33,12.99,-0.0372753496410921,0.790271127534798,"*",0.700182,"WRB","NA","NA","NA","NA","XP_017381756.1//PREDICTED: tail-anchored protein insertion receptor WRB isoform X5 [Cebus capucinus imitator];NP_001337222.1//tail-anchored protein insertion receptor WRB isoform 3 [Homo sapiens];XP_017381755.1//PREDICTED: tail-anchored protein insertion receptor WRB isoform X4 [Cebus capucinus imitator];AAI11394.1//WRB protein, partial [Homo sapiens];XP_008984946.1//PREDICTED: tail-anchored protein insertion receptor WRB isoform X2 [Callithrix jacchus];XP_016793878.1//PREDICTED: tail-anchored protein insertion receptor WRB isoform X1 [Pan troglodytes]","1//3;2//1;5"]
[6903,1675,8.24,8.03,-0.0372443496659041,0.867887373929591,"*",0.79943,"TBCC","GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0032391//photoreceptor connecting cilium;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0015631//tubulin binding;GO:0051087//chaperone binding;GO:0003924//GTPase activity","GO:0006457//protein folding;GO:0007021//tubulin complex assembly;GO:0007023//post-chaperonin tubulin folding pathway","K21766//tubulin-specific chaperone C","EAX04100.1//tubulin-specific chaperone c [Homo sapiens]","2//1"]
[318,925,11.94,11.64,-0.036711778356521,0.921513201249917,"*",0.86769,"NUDT2","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0004081//bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity;GO:0008803//bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity;GO:0005525//GTP binding;GO:0008796//bis(5'-nucleosyl)-tetraphosphatase activity","GO:0034599//cellular response to oxidative stress;GO:0006139//nucleobase-containing compound metabolic process;GO:0006915//apoptotic process","K01518//bis(5'-nucleosidyl)-tetraphosphatase [EC:3.6.1.17]","XP_007967165.1//PREDICTED: bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] isoform X2 [Chlorocebus sabaeus];NP_001152.1//NUDT2 gene product [Homo sapiens];XP_005581528.2//PREDICTED: bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] isoform X1 [Macaca fascicularis]","4;1//3;2//1"]
[22926,7563,6.77,6.6,-0.0366898093291809,0.777788498676018,"*",0.680358,"ATF6","GO:0016020//membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005783//endoplasmic reticulum;GO:0005635//nuclear envelope;GO:0000139//Golgi membrane;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005789//endoplasmic reticulum membrane","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0042802//identical protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0046982//protein heterodimerization activity;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0003713//transcription coactivator activity;GO:0035497//cAMP response element binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0006457//protein folding;GO:0007165//signal transduction;GO:0006990//positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response;GO:0001654//eye development;GO:0006950//response to stress;GO:0007601//visual perception;GO:1990440//positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0043065//positive regulation of apoptotic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0036500//ATF6-mediated unfolded protein response","K09054//cyclic AMP-dependent transcription factor ATF-6 alpha","NP_031374.2//cyclic AMP-dependent transcription factor ATF-6 alpha [Homo sapiens]","3//A2MP1"]
[3678,4267,16.36,15.95,-0.036616324289517,0.734475678778536,"*",0.626378,"ITGA5","NA","NA","NA","K06484//integrin alpha 5","EAW96781.1//integrin, alpha 5 (fibronectin receptor, alpha polypeptide), isoform CRA_b [Homo sapiens]",4]
[140803,8250,0.8,0.78,-0.036525876025114,0.98306563287031,"*",0.94811,"TRPM6","GO:0016324//apical plasma membrane;GO:0031526//brush border membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0046872//metal ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0005262//calcium channel activity;GO:0005261//cation channel activity","GO:0070588//calcium ion transmembrane transport;GO:0051262//protein tetramerization;GO:0030001//metal ion transport;GO:0009636//response to toxic substance","K04981//transient receptor potential cation channel subfamily M member 6 [EC:2.7.11.1]","NP_001170781.1//transient receptor potential cation channel subfamily M member 6 isoform b [Homo sapiens];NP_060132.3//transient receptor potential cation channel subfamily M member 6 isoform a [Homo sapiens];NP_001170782.1//transient receptor potential cation channel subfamily M member 6 isoform c [Homo sapiens]","4;1//3"]
[51696,5621,1.2,1.17,-0.036525876025114,0.937508843051699,"*",0.88774,"HECA","GO:0016020//membrane;GO:0005634//nucleus;GO:0005737//cytoplasm","NA","GO:0045930//negative regulation of mitotic cell cycle;GO:0030323//respiratory tube development","K03129//transcription initiation factor TFIID subunit 4;K11305//histone acetyltransferase MYST3 [EC:2.3.1.48]","NP_057301.1//headcase protein homolog [Homo sapiens]","2//1"]
[6642,8332,11.22,10.94,-0.0364599378162364,0.684626577024881,"*",0.566722,"SNX1","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0010008//endosome membrane;GO:0030904//retromer complex;GO:0019898//extrinsic component of membrane;GO:0005764//lysosome;GO:0031982//vesicle;GO:0030027//lamellipodium;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0030905//retromer, tubulation complex;GO:0031901//early endosome membrane;GO:0043234//protein complex;GO:0005829//cytosol;GO:0005794//Golgi apparatus","GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity;GO:0005154//epidermal growth factor receptor binding;GO:0042803//protein homodimerization activity;GO:0035091//phosphatidylinositol binding;GO:0045296//cadherin binding;GO:1990460//leptin receptor binding;GO:1990459//transferrin receptor binding;GO:0005158//insulin receptor binding","GO:0031623//receptor internalization;GO:0042147//retrograde transport, endosome to Golgi;GO:0034498//early endosome to Golgi transport;GO:0006886//intracellular protein transport;GO:0016050//vesicle organization;GO:0045732//positive regulation of protein catabolic process;GO:0006897//endocytosis;GO:0072673//lamellipodium morphogenesis","K17917//sorting nexin-1/2","NP_001229862.1//sorting nexin-1 isoform d [Homo sapiens];XP_021569415.1//sorting nexin-1 isoform X3 [Carlito syrichta];NP_003090.2//sorting nexin-1 isoform a [Homo sapiens]","1//3;4;3//A2MP1"]
[5356,3374,10.84,10.57,-0.0363893799711885,0.818884347910728,"*",0.737324,"PLRG1","GO:0080008//Cul4-RING E3 ubiquitin ligase complex;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0000974//Prp19 complex;GO:0016607//nuclear speck;GO:0071013//catalytic step 2 spliceosome;GO:0001650//fibrillar center;GO:0071011//precatalytic spliceosome;GO:0005662//DNA replication factor A complex","NA","GO:1900087//positive regulation of G1/S transition of mitotic cell cycle;GO:0000398//mRNA splicing, via spliceosome;GO:0034504//protein localization to nucleus","K12862//pleiotropic regulator 1","NP_002660.1//pleiotropic regulator 1 isoform 1 [Homo sapiens];NP_001188493.1//pleiotropic regulator 1 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[79697,2502,16.89,16.47,-0.036328773075031,0.799638059146599,"*",0.710934,"RIOX1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus","GO:0032453//histone demethylase activity (H3-K4 specific);GO:0051864//histone demethylase activity (H3-K36 specific);GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;GO:0005506//iron ion binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0030961//peptidyl-arginine hydroxylation;GO:0006338//chromatin remodeling;GO:0045668//negative regulation of osteoblast differentiation;GO:0006351//transcription, DNA-templated;GO:0070544//histone H3-K36 demethylation;GO:0034720//histone H3-K4 demethylation","K16914//bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66 [EC:1.14.11.- 1.14.11.27]","XP_012359781.1//PREDICTED: LOW QUALITY PROTEIN: bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66 [Nomascus leucogenys]",4]
[4190,1482,87.75,85.57,-0.0362940348335387,0.64305488133631,"*",0.48682,"MDH1","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0043209//myelin sheath;GO:0005739//mitochondrion","GO:0047860//diiodophenylpyruvate reductase activity;GO:0004470//malic enzyme activity;GO:0051287//NAD binding;GO:0030060//L-malate dehydrogenase activity","GO:0006099//tricarboxylic acid cycle;GO:0006107//oxaloacetate metabolic process;GO:0006094//gluconeogenesis;GO:0005975//carbohydrate metabolic process;GO:0006734//NADH metabolic process;GO:0006108//malate metabolic process","K00025//malate dehydrogenase [EC:1.1.1.37]","NP_001186040.1//malate dehydrogenase, cytoplasmic isoform 2 [Homo sapiens];NP_001303303.1//malate dehydrogenase, peroxisomal isoform MDH1x [Homo sapiens]","1//3;3//A2MP1"]
[122961,1088,24.65,24.04,-0.0361507505540884,0.846095890489914,"*",0.771942,"ISCA2","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0051537//2 iron, 2 sulfur cluster binding;GO:0005506//iron ion binding;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0005198//structural molecule activity","GO:0097428//protein maturation by iron-sulfur cluster transfer;GO:0016226//iron-sulfur cluster assembly;GO:0051604//protein maturation;GO:0044281//small molecule metabolic process","K22072//iron-sulfur cluster assembly 2","CAD62580.1//unnamed protein product, partial [Homo sapiens]","1//3;3//A2MP1"]
[115353,1789,13.74,13.4,-0.0361490034729654,0.91301387095054,"*",0.857458,"LRRC42","NA","NA","NA","NA","XP_017359914.1//PREDICTED: leucine-rich repeat-containing protein 42 isoform X1 [Cebus capucinus imitator];NP_443172.1//leucine-rich repeat-containing protein 42 [Homo sapiens]","1//3;4"]
[80213,1374,14.55,14.19,-0.036144563735095,0.734197789312977,"*",0.632208,"TM2D3","GO:0016021//integral component of membrane","NA","NA","K01868//threonyl-tRNA synthetase [EC:6.1.1.3];K09488//TNF receptor-associated protein 1;K03511//DNA polymerase kappa [EC:2.7.7.7]","NP_001294889.1//TM2 domain-containing protein 3 isoform c precursor [Homo sapiens];NP_510883.2//TM2 domain-containing protein 3 isoform a precursor [Homo sapiens];EAX02314.1//TM2 domain containing 3, isoform CRA_b [Homo sapiens];NP_001294955.1//TM2 domain-containing protein 3 isoform d precursor [Homo sapiens]","1//3;3//A2MP1;2//1"]
[56983,3552,3.64,3.55,-0.0361194258066521,0.897443687663514,"*",0.837498,"POGLUT1","GO:0070062//extracellular exosome;GO:0005788//endoplasmic reticulum lumen","GO:0035252//UDP-xylosyltransferase activity;GO:0046527//glucosyltransferase activity;GO:0030158//protein xylosyltransferase activity;GO:0035251//UDP-glucosyltransferase activity","GO:0007369//gastrulation;GO:0045747//positive regulation of Notch signaling pathway;GO:0018242//protein O-linked glycosylation via serine;GO:0010470//regulation of gastrulation;GO:0060537//muscle tissue development;GO:0006664//glycolipid metabolic process;GO:0072358//cardiovascular system development;GO:0006493//protein O-linked glycosylation;GO:0001756//somitogenesis;GO:0048318//axial mesoderm development;GO:0048339//paraxial mesoderm development","K13667//protein glucosyltransferase [EC:2.4.1.-]","NP_689518.1//protein O-glucosyltransferase 1 precursor [Homo sapiens]","2//1"]
[51540,2544,17.89,17.45,-0.0359263509548938,0.790593386832439,"*",0.700616,"SCLY","GO:1902494//catalytic complex;GO:0005829//cytosol","GO:0070279//vitamin B6 binding;GO:0016829//lyase activity;GO:0009000//selenocysteine lyase activity;GO:0016597//amino acid binding;GO:0016740//transferase activity;GO:0042803//protein homodimerization activity","GO:0016261//selenocysteine catabolic process;GO:0006520//cellular amino acid metabolic process;GO:0001887//selenium compound metabolic process","K01763//selenocysteine lyase [EC:4.4.1.16]","NP_057594.4//selenocysteine lyase [Homo sapiens]",5]
[119504,3535,24,23.41,-0.0359094713838681,0.787991135295783,"*",0.697126,"ANAPC16","GO:0005829//cytosol;GO:0000776//kinetochore;GO:0000777//condensed chromosome kinetochore;GO:0005680//anaphase-promoting complex","NA","GO:0051301//cell division;GO:0016567//protein ubiquitination;GO:0007049//cell cycle","K01064//wingless-type MMTV integration site family, member 9","EHH20263.1//hypothetical protein EGK_03078, partial [Macaca mulatta];XP_006027950.1//PREDICTED: anaphase-promoting complex subunit 16 isoform X1 [Alligator sinensis];XP_011586098.1//PREDICTED: anaphase-promoting complex subunit 16 [Aquila chrysaetos canadensis]","1//3;3//A2MP1"]
[10969,1402,69.63,67.93,-0.0356601692172749,0.729933537182852,"*",0.626754,"EBNA1BP2","GO:0005634//nucleus;GO:0005730//nucleolus;GO:0034399//nuclear periphery;GO:0030687//preribosome, large subunit precursor","GO:0003723//RNA binding","GO:0006364//rRNA processing;GO:0042273//ribosomal large subunit biogenesis","K14823//rRNA-processing protein EBP2","XP_010370159.1//PREDICTED: probable rRNA-processing protein EBP2 [Rhinopithecus roxellana];XP_003812904.1//PREDICTED: probable rRNA-processing protein EBP2 [Pan paniscus]","1//3;2//1"]
[26097,2133,31.72,30.95,-0.0354533616023514,0.738406094090315,"*",0.63671,"CHTOP","GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0016607//nuclear speck;GO:0036464//cytoplasmic ribonucleoprotein granule;GO:0000346//transcription export complex","GO:0003723//RNA binding;GO:0008327//methyl-CpG binding","GO:0006406//mRNA export from nucleus;GO:0031062//positive regulation of histone methylation;GO:0006355//regulation of transcription, DNA-templated;GO:0006369//termination of RNA polymerase II transcription;GO:0031124//mRNA 3'-end processing;GO:0051096//positive regulation of helicase activity;GO:0006405//RNA export from nucleus;GO:0032781//positive regulation of ATPase activity;GO:0008284//positive regulation of cell proliferation","K08580//calpain-11 [EC:3.4.22.-];K12881//THO complex subunit 4;K13098//RNA-binding protein FUS;K12323//atrial natriuretic peptide receptor A [EC:4.6.1.2];K14859//ribosome biogenesis protein SSF1/2","OWK04629.1//hypothetical protein Celaphus_00001983, partial [Cervus elaphus hippelaphus]","1//3;3//A2MP1"]
[10325,2143,4.12,4.02,-0.0354488360042899,0.583479411001025,"*",0.427656,"RRAGB","GO:0005765//lysosomal membrane;GO:0005634//nucleus;GO:1990131//Gtr1-Gtr2 GTPase complex;GO:0034448//EGO complex;GO:0005829//cytosol;GO:0005764//lysosome;GO:0005737//cytoplasm","GO:0032561//guanyl ribonucleotide binding;GO:0046982//protein heterodimerization activity;GO:0051020//GTPase binding;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0016241//regulation of macroautophagy;GO:1904263//positive regulation of TORC1 signaling;GO:0034198//cellular response to amino acid starvation;GO:0032006//regulation of TOR signaling;GO:1990253//cellular response to leucine starvation;GO:0009267//cellular response to starvation;GO:0032008//positive regulation of TOR signaling;GO:0007050//cell cycle arrest;GO:0071230//cellular response to amino acid stimulus;GO:0034613//cellular protein localization;GO:0010506//regulation of autophagy","K16185//Ras-related GTP-binding protein A/B","NP_057740.2//ras-related GTP-binding protein B long isoform [Homo sapiens];XP_012891202.1//PREDICTED: ras-related GTP-binding protein B isoform X2 [Dipodomys ordii];NP_006055.3//ras-related GTP-binding protein B short isoform [Homo sapiens];XP_019524808.1//PREDICTED: ras-related GTP-binding protein B isoform X2 [Hipposideros armiger]","1//3;4;3//A2MP1"]
[29785,2660,52.34,51.07,-0.0354378653356189,0.631584338394794,"*",0.51036,"CYP2S1","GO:0005783//endoplasmic reticulum;GO:0031090//organelle membrane;GO:0005789//endoplasmic reticulum membrane","GO:0008395//steroid hydroxylase activity;GO:0020037//heme binding;GO:0008401//retinoic acid 4-hydroxylase activity;GO:0005506//iron ion binding;GO:0070330//aromatase activity;GO:0008392//arachidonic acid epoxygenase activity","GO:0019373//epoxygenase P450 pathway","K07420//cytochrome P450 family 2 subfamily S polypeptide 1 [EC:1.14.14.1]","BAB55227.1//unnamed protein product [Homo sapiens]",7]
[23478,1429,152.2,148.51,-0.0354082799051493,0.582829290952707,"*",0.425866,"SEC11A","GO:0070062//extracellular exosome;GO:0031090//organelle membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005787//signal peptidase complex","GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity","GO:0006465//signal peptide processing","K13280//signal peptidase I [EC:3.4.21.89]","XP_014444976.1//PREDICTED: signal peptidase complex catalytic subunit SEC11A [Tupaia chinensis];NP_001258848.1//signal peptidase complex catalytic subunit SEC11A isoform 6 [Homo sapiens];NP_001258850.1//signal peptidase complex catalytic subunit SEC11A isoform 1 [Homo sapiens];NP_001258851.1//signal peptidase complex catalytic subunit SEC11A isoform 3 [Homo sapiens];AAP97204.1//signal peptidase complex SPC-18 [Homo sapiens]","1//3;3//A2MP1"]
[55813,2065,19.42,18.95,-0.0353453523607383,0.810848420905338,"*",0.72552,"UTP6","GO:0034388//Pwp2p-containing subcomplex of 90S preribosome;GO:0005654//nucleoplasm;GO:0032040//small-subunit processome;GO:0005730//nucleolus","GO:0030515//snoRNA binding","GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006364//rRNA processing","K14557//U3 small nucleolar RNA-associated protein 6","NP_060898.2//U3 small nucleolar RNA-associated protein 6 homolog [Homo sapiens]","2//1"]
[83742,3250,51.41,50.17,-0.03522407398603,0.632317241218578,"*",0.475564,"MARVELD1","GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0045121//membrane raft;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0019911//structural constituent of myelin sheath","GO:0042552//myelination;GO:0001766//membrane raft polarization;GO:0008104//protein localization;GO:0007049//cell cycle","K22022//mucin-21;K14316//nuclear pore complex protein Nup121","NP_113672.1//MARVEL domain-containing protein 1 [Homo sapiens]","3//A2MP1"]
[50485,3150,10.03,9.79,-0.0349408410084857,0.885632336861978,"*",0.822262,"SMARCAL1","GO:0035861//site of double-strand break;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005662//DNA replication factor A complex","GO:0036310//annealing helicase activity;GO:0005524//ATP binding;GO:0004386//helicase activity;GO:0008094//DNA-dependent ATPase activity","GO:0090656//t-circle formation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006281//DNA repair;GO:0031297//replication fork processing;GO:0006259//DNA metabolic process;GO:0006974//cellular response to DNA damage stimulus","K14440//SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 [EC:3.6.4.12]","NP_054859.2//SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 [Homo sapiens]","1//3;3//A2MP1"]
[51626,1432,8.36,8.16,-0.034933790109387,0.925060067729084,"*",0.87213,"DYNC2LI1","GO:0005929//cilium;GO:0005874//microtubule;GO:0035869//ciliary transition zone;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0036064//ciliary basal body;GO:0097542//ciliary tip;GO:0031514//motile cilium;GO:0030990//intraciliary transport particle;GO:0005868//cytoplasmic dynein complex;GO:0045177//apical part of cell;GO:0005930//axoneme","GO:0003774//motor activity;GO:0008569//ATP-dependent microtubule motor activity, minus-end-directed;GO:0045504//dynein heavy chain binding","GO:0007368//determination of left/right symmetry;GO:1902017//regulation of cilium assembly;GO:0035735//intraciliary transport involved in cilium assembly;GO:0035721//intraciliary retrograde transport","K10417//dynein light intermediate chain 2, cytosolic","NP_056337.1//cytoplasmic dynein 2 light intermediate chain 1 isoform 2 [Homo sapiens];NP_001335842.1//cytoplasmic dynein 2 light intermediate chain 1 isoform 6 [Homo sapiens];NP_057092.2//cytoplasmic dynein 2 light intermediate chain 1 isoform 1 [Homo sapiens];NP_001335841.1//cytoplasmic dynein 2 light intermediate chain 1 isoform 5 [Homo sapiens];NP_001180393.1//cytoplasmic dynein 2 light intermediate chain 1 isoform 4 [Homo sapiens]","1//3;3//A2MP1"]
[2997,3502,26.38,25.75,-0.0348721322936016,0.750112512946622,"*",0.649246,"GYS1","GO:0016020//membrane;GO:0005829//cytosol;GO:0016234//inclusion body","GO:0004373//glycogen (starch) synthase activity;GO:0061547//glycogen synthase activity, transferring glucose-1-phosphate;GO:0005536//glucose binding;GO:0019901//protein kinase binding","GO:0005978//glycogen biosynthetic process;GO:0007507//heart development","K00693//glycogen synthase [EC:2.4.1.11]","NP_001155059.1//glycogen [starch] synthase, muscle isoform 2 [Homo sapiens];NP_002094.2//glycogen [starch] synthase, muscle isoform 1 [Homo sapiens]","1//3;4"]
[8999,4963,0.42,0.41,-0.0347654181606766,1.02146076861736,"*",0.994348,"CDKL2","GO:0005634//nucleus;GO:0005813//centrosome;GO:0005737//cytoplasm","GO:0004674//protein serine/threonine kinase activity;GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity","GO:0007548//sex differentiation;GO:0007165//signal transduction;GO:1903955//positive regulation of protein targeting to mitochondrion","K08824//cyclin-dependent kinase-like [EC:2.7.11.22]","NP_003939.1//cyclin-dependent kinase-like 2 isoform 1 [Homo sapiens];NP_001317653.1//cyclin-dependent kinase-like 2 isoform 2 [Homo sapiens]","1//3;4"]
[284427,1669,0.42,0.41,-0.0347654181606766,1.01909703225806,"*",0.996768,"SLC25A41","GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion","GO:0005347//ATP transmembrane transporter activity;GO:0015217//ADP transmembrane transporter activity","GO:0055085//transmembrane transport;GO:0006839//mitochondrial transport","K14684//solute carrier family 25 (mitochondrial phosphate transporter), member 23/24/25/41","NP_775908.2//solute carrier family 25 member 41 isoform a [Homo sapiens];EAW69094.1//hypothetical protein MGC34725, isoform CRA_b [Homo sapiens]","1//3;3//A2MP1"]
[4796,4519,19.36,18.9,-0.0346927181661596,0.709210759784882,"*",0.594398,"TONSL","GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0043596//nuclear replication fork;GO:0005737//cytoplasm","GO:0042393//histone binding;GO:0003714//transcription corepressor activity","GO:0042994//cytoplasmic sequestering of transcription factor;GO:0031297//replication fork processing;GO:0000724//double-strand break repair via homologous recombination","K09257//NF-kappa-B inhibitor-like protein 2","NP_038460.4//tonsoku-like protein [Homo sapiens]",4]
[28969,1872,35.19,34.36,-0.0344354776112011,0.732654728571429,"*",0.629274,"BZW2","GO:0016020//membrane;GO:0005737//cytoplasm","GO:0045296//cadherin binding","NA","K03260//translation initiation factor 4G;K03240//translation initiation factor eIF-2B subunit epsilon","XP_004431470.1//PREDICTED: basic leucine zipper and W2 domain-containing protein 2 isoform X1 [Ceratotherium simum simum];XP_518982.5//PREDICTED: basic leucine zipper and W2 domain-containing protein 2 isoform X1 [Pan troglodytes]","1//3;2//1"]
[57570,5419,4.68,4.57,-0.0343143645253347,0.636117349269588,"*",0.479776,"TRMT5","GO:0005759//mitochondrial matrix;GO:0005634//nucleus","GO:0052906//tRNA (guanine(37)-N(1))-methyltransferase activity","GO:0070901//mitochondrial tRNA methylation","K15429//tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]","NP_001337183.1//tRNA (guanine(37)-N1)-methyltransferase isoform 2 [Homo sapiens];XP_007985084.1//PREDICTED: tRNA (guanine(37)-N1)-methyltransferase [Chlorocebus sabaeus];NP_001337182.1//tRNA (guanine(37)-N1)-methyltransferase isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[22907,4114,24.71,24.13,-0.0342670951130332,0.689068271012524,"*",0.571736,"DHX30","GO:0042645//mitochondrial nucleoid;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0035770//ribonucleoprotein granule","GO:0003723//RNA binding;GO:0004004//ATP-dependent RNA helicase activity;GO:0005524//ATP binding;GO:0003682//chromatin binding;GO:0004386//helicase activity;GO:0003725//double-stranded RNA binding;GO:0003676//nucleic acid binding","GO:0006396//RNA processing;GO:1902775//mitochondrial large ribosomal subunit assembly","K13185//ATP-dependent RNA helicase DHX30 [EC:3.6.4.13]","NP_619520.1//putative ATP-dependent RNA helicase DHX30 isoform 1 [Homo sapiens];XP_016861403.1//PREDICTED: putative ATP-dependent RNA helicase DHX30 isoform X2 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[27077,1800,26.46,25.84,-0.0342069915847519,0.815368038156246,"*",0.733086,"B9D1","GO:0016020//membrane;GO:0036064//ciliary basal body;GO:0005829//cytosol;GO:0035869//ciliary transition zone;GO:0005813//centrosome;GO:0036038//MKS complex","GO:0008158//hedgehog receptor activity","GO:0043010//camera-type eye development;GO:0001701//in utero embryonic development;GO:0042733//embryonic digit morphogenesis;GO:0001944//vasculature development;GO:0060271//cilium assembly;GO:0097711//ciliary basal body-plasma membrane docking;GO:0032880//regulation of protein localization;GO:0007224//smoothened signaling pathway;GO:0060563//neuroepithelial cell differentiation","K16744//B9 domain-containing protein 1","NP_001230402.1//B9 domain-containing protein 1 isoform a [Homo sapiens];EAW50880.1//B9 protein, isoform CRA_c [Homo sapiens];EAW50878.1//B9 protein, isoform CRA_a [Homo sapiens];EAW50879.1//B9 protein, isoform CRA_b [Homo sapiens]","4;1//3;2//1"]
[3684,4742,0.43,0.42,-0.0339473319233377,0.942640751812311,"*",0.895432,"ITGAM","GO:0070062//extracellular exosome;GO:0034688//integrin alphaM-beta2 complex;GO:0005615//extracellular space;GO:0009897//external side of plasma membrane;GO:0044853//plasma membrane raft;GO:0008305//integrin complex;GO:0009986//cell surface;GO:0035579//specific granule membrane;GO:0070821//tertiary granule membrane;GO:0005886//plasma membrane","GO:0046872//metal ion binding;GO:0031072//heat shock protein binding;GO:0001851//complement component C3b binding;GO:0046982//protein heterodimerization activity","GO:0032930//positive regulation of superoxide anion generation;GO:0006911//phagocytosis, engulfment;GO:0097242//amyloid-beta clearance;GO:2000363//positive regulation of prostaglandin-E synthase activity;GO:0043312//neutrophil degranulation;GO:0007229//integrin-mediated signaling pathway;GO:0001774//microglial cell activation;GO:0034142//toll-like receptor 4 signaling pathway;GO:0050900//leukocyte migration;GO:1903980//positive regulation of microglial cell activation;GO:1901216//positive regulation of neuron death;GO:0010668//ectodermal cell differentiation;GO:0043315//positive regulation of neutrophil degranulation;GO:0007155//cell adhesion;GO:0045963//negative regulation of dopamine metabolic process;GO:0030198//extracellular matrix organization;GO:0098742//cell-cell adhesion via plasma-membrane adhesion molecules;GO:0090314//positive regulation of protein targeting to membrane","K06461//integrin alpha M","NP_001139280.1//integrin alpha-M isoform 1 precursor [Homo sapiens];XP_008957894.1//PREDICTED: integrin alpha-M isoform X2 [Pan paniscus]","1//3;3//A2MP1"]
[5707,3329,74.07,72.36,-0.0336969292426969,0.561906825220856,"*",0.406146,"PSMD1","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000502//proteasome complex;GO:0022624//proteasome accessory complex;GO:0005838//proteasome regulatory particle;GO:0034515//proteasome storage granule;GO:0035578//azurophil granule lumen;GO:0005829//cytosol;GO:0005576//extracellular region;GO:0008540//proteasome regulatory particle, base subcomplex","GO:0030234//enzyme regulator activity","GO:0043687//post-translational protein modification;GO:0038061//NIK/NF-kappaB signaling;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0006521//regulation of cellular amino acid metabolic process;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0016579//protein deubiquitination;GO:0043312//neutrophil degranulation;GO:0043488//regulation of mRNA stability;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0000209//protein polyubiquitination;GO:0055085//transmembrane transport;GO:0000165//MAPK cascade;GO:0050852//T cell receptor signaling pathway;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0042176//regulation of protein catabolic process;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:1902036//regulation of hematopoietic stem cell differentiation","K03032//26S proteasome regulatory subunit N2","XP_008528275.1//PREDICTED: 26S proteasome non-ATPase regulatory subunit 1 isoform X2 [Equus przewalskii];NP_001177966.1//26S proteasome non-ATPase regulatory subunit 1 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[5164,2444,14.75,14.41,-0.0336446189618184,0.782014634803574,"*",0.69037,"PDK2","GO:0005759//mitochondrial matrix;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005967//mitochondrial pyruvate dehydrogenase complex","GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0004672//protein kinase activity;GO:0004740//pyruvate dehydrogenase (acetyl-transferring) kinase activity;GO:0042803//protein homodimerization activity","GO:0010565//regulation of cellular ketone metabolic process;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:0006006//glucose metabolic process;GO:0008286//insulin receptor signaling pathway;GO:0034614//cellular response to reactive oxygen species;GO:0006885//regulation of pH;GO:0006111//regulation of gluconeogenesis;GO:0010510//regulation of acetyl-CoA biosynthetic process from pyruvate;GO:0031670//cellular response to nutrient;GO:0042593//glucose homeostasis;GO:0010906//regulation of glucose metabolic process","K00898//pyruvate dehydrogenase kinase 2/3/4 [EC:2.7.11.2]","XP_523791.4//PREDICTED: pyruvate dehydrogenase kinase, isozyme 2 isoform X1 [Pan troglodytes];XP_003281289.2//PREDICTED: pyruvate dehydrogenase kinase, isozyme 2 isoform X1 [Nomascus leucogenys]","4;1//3"]
[60682,3253,9.12,8.91,-0.0336083926428195,0.775875750161163,"*",0.678102,"SMAP1","GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0046872//metal ion binding;GO:0030276//clathrin binding;GO:0005096//GTPase activator activity","GO:0045648//positive regulation of erythrocyte differentiation;GO:2000369//regulation of clathrin-dependent endocytosis","K12486//stromal membrane-associated protein","NP_001037770.1//stromal membrane-associated protein 1 isoform A [Homo sapiens];NP_068759.2//stromal membrane-associated protein 1 isoform B [Homo sapiens];NP_001268368.1//stromal membrane-associated protein 1 isoform C [Homo sapiens];NP_001268369.1//stromal membrane-associated protein 1 isoform D [Homo sapiens]","4;1//3;2//1"]
[284370,3835,0.87,0.85,-0.0335525597110265,0.831783006358861,"*",0.753364,"ZNF615","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","NP_940882.3//zinc finger protein 615 isoform 2 [Homo sapiens];NP_001308252.1//zinc finger protein 615 isoform 5 [Homo sapiens];NP_001308246.1//zinc finger protein 615 isoform 3 [Homo sapiens];NP_001186253.1//zinc finger protein 615 isoform 1 [Homo sapiens];NP_001308251.1//zinc finger protein 615 isoform 4 [Homo sapiens];NP_001308247.1//zinc finger protein 615 isoform 4 [Homo sapiens]","1//3;3//A2MP1"]
[89848,4333,4.81,4.7,-0.0333761372050423,0.87620360170697,"*",0.809778,"FCHSD1","GO:0031594//neuromuscular junction;GO:0055037//recycling endosome","NA","GO:0030833//regulation of actin filament polymerization;GO:0007274//neuromuscular synaptic transmission","K20125//F-BAR and double SH3 domains protein","NP_258260.1//F-BAR and double SH3 domains protein 1 [Homo sapiens]","2//1"]
[389333,3251,0.88,0.86,-0.0331668639351993,0.95541517625475,"*",0.91283,"PROB1","NA","NA","NA","K16628//collagen, type VII, alpha;K22020//mucin-19","NP_001155018.1//proline-rich basic protein 1 [Homo sapiens]","1//3"]
[80832,3251,1.76,1.72,-0.0331668639351993,0.978560407202756,"*",0.942356,"APOL4","GO:0043231//intracellular membrane-bounded organelle;GO:0005615//extracellular space","GO:0008289//lipid binding","GO:0006869//lipid transport;GO:0042157//lipoprotein metabolic process;GO:0006629//lipid metabolic process","K14480//apolipoprotein L","NP_663693.1//apolipoprotein L4 isoform 2 precursor [Homo sapiens];NP_085146.2//apolipoprotein L4 isoform 1 [Homo sapiens]","4;2//1"]
[79623,2732,26.45,25.85,-0.0331034417990909,0.780490987631372,"*",0.683406,"GALNT14","GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0004653//polypeptide N-acetylgalactosaminyltransferase activity;GO:0046872//metal ion binding;GO:0030246//carbohydrate binding;GO:0016757//transferase activity, transferring glycosyl groups","GO:0006486//protein glycosylation;GO:0016266//O-glycan processing","K00710//polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41]","NP_001240756.1//polypeptide N-acetylgalactosaminyltransferase 14 isoform 3 [Homo sapiens];XP_016860395.1//PREDICTED: polypeptide N-acetylgalactosaminyltransferase 14 isoform X1 [Homo sapiens];NP_001240755.1//polypeptide N-acetylgalactosaminyltransferase 14 isoform 2 [Homo sapiens];NP_078848.2//polypeptide N-acetylgalactosaminyltransferase 14 isoform 1 [Homo sapiens];NP_001316026.1//polypeptide N-acetylgalactosaminyltransferase 14 isoform 6 [Homo sapiens]","1//3;3//A2MP1"]
[55108,3361,11.06,10.81,-0.0329848625000567,0.550253289535593,"*",0.395346,"BSDC1","NA","NA","NA","K20858//calcium uniporter protein, mitochondrial","NP_001137361.1//BSD domain-containing protein 1 isoform c [Homo sapiens];NP_001137362.1//BSD domain-containing protein 1 isoform d [Homo sapiens];NP_001137360.1//BSD domain-containing protein 1 isoform a [Homo sapiens];NP_060515.3//BSD domain-containing protein 1 isoform b [Homo sapiens];NP_001287887.1//BSD domain-containing protein 1 isoform e [Homo sapiens]","1//3;7;2//1"]
[389084,2786,6.21,6.07,-0.0328967519647993,0.889563554208754,"*",0.82697,"SNORC","NA","NA","NA","K16628//collagen, type VII, alpha;K06236//collagen, type I, alpha;K22020//mucin-19","XP_008963975.1//PREDICTED: uncharacterized protein LOC100977774 [Pan paniscus];XP_016859569.1//PREDICTED: uncharacterized protein C2orf82 isoform X1 [Homo sapiens]","1//3;2//1"]
[11149,5589,2.22,2.17,-0.0328646339056268,0.7914603183391,"*",0.701632,"BVES","GO:0005901//caveola;GO:0042383//sarcolemma;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0005923//bicellular tight junction;GO:0016328//lateral plasma membrane;GO:0005886//plasma membrane","GO:0030552//cAMP binding;GO:0005198//structural molecule activity","GO:0002931//response to ischemia;GO:0090136//epithelial cell-cell adhesion;GO:0034446//substrate adhesion-dependent cell spreading;GO:0001921//positive regulation of receptor recycling;GO:0007507//heart development;GO:0007517//muscle organ development;GO:0008360//regulation of cell shape;GO:0040017//positive regulation of locomotion;GO:0016192//vesicle-mediated transport;GO:0043087//regulation of GTPase activity;GO:0007519//skeletal muscle tissue development","K21108//blood vessel epicardial substance","XP_011808261.1//PREDICTED: blood vessel epicardial substance isoform X1 [Colobus angolensis palliatus];NP_671488.1//blood vessel epicardial substance [Homo sapiens]","1//3;4;3//A2MP1"]
[93010,3641,0.89,0.87,-0.0327899351176695,0.960379282051282,"*",0.919136,"B3GNT7","GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0008499//UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity;GO:0008532//N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity","GO:0018146//keratan sulfate biosynthetic process;GO:0016266//O-glycan processing","K09664//beta-1,3-N-acetylglucosaminyltransferase 7 [EC:2.4.1.-]","NP_660279.1//UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7 [Homo sapiens]","2//1"]
[182,5988,12.53,12.25,-0.0326046654319276,0.758111989329488,"*",0.658258,"JAG1","GO:0016020//membrane;GO:0005887//integral component of plasma membrane;GO:0016324//apical plasma membrane;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005912//adherens junction","GO:0008083//growth factor activity;GO:0005509//calcium ion binding;GO:0005112//Notch binding;GO:0005198//structural molecule activity;GO:0005543//phospholipid binding","GO:0072070//loop of Henle development;GO:0045747//positive regulation of Notch signaling pathway;GO:0061309//cardiac neural crest cell development involved in outflow tract morphogenesis;GO:0042127//regulation of cell proliferation;GO:0045445//myoblast differentiation;GO:0045446//endothelial cell differentiation;GO:0061073//ciliary body morphogenesis;GO:0003215//cardiac right ventricle morphogenesis;GO:0060411//cardiac septum morphogenesis;GO:0001525//angiogenesis;GO:0045599//negative regulation of fat cell differentiation;GO:0001974//blood vessel remodeling;GO:0072006//nephron development;GO:0042491//inner ear auditory receptor cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007220//Notch receptor processing;GO:0072015//glomerular visceral epithelial cell development;GO:0007219//Notch signaling pathway;GO:0097150//neuronal stem cell population maintenance;GO:0007399//nervous system development;GO:0030216//keratinocyte differentiation;GO:0002456//T cell mediated immunity;GO:0061156//pulmonary artery morphogenesis;GO:0035909//aorta morphogenesis;GO:0003184//pulmonary valve morphogenesis;GO:0061444//endocardial cushion cell development;GO:0002011//morphogenesis of an epithelial sheet;GO:0072017//distal tubule development;GO:0030334//regulation of cell migration;GO:0030097//hemopoiesis;GO:0061314//Notch signaling involved in heart development;GO:0045602//negative regulation of endothelial cell differentiation;GO:0001709//cell fate determination;GO:0032495//response to muramyl dipeptide;GO:0045639//positive regulation of myeloid cell differentiation;GO:0045669//positive regulation of osteoblast differentiation;GO:2000737//negative regulation of stem cell differentiation;GO:0045665//negative regulation of neuron differentiation","K06052//jagged-1","NP_000205.1//protein jagged-1 precursor [Homo sapiens]","2//1"]
[11161,1576,48.78,47.69,-0.0326029754018265,0.758289960348929,"*",0.65846,"ERG28","GO:0016021//integral component of membrane","NA","NA","NA","AAF28966.1//HSPC288, partial [Homo sapiens]","3//A2MP1"]
[55063,2372,0.9,0.88,-0.0324214776923775,0.94415323139734,"*",0.897578,"ZCWPW1","NA","GO:0008270//zinc ion binding","NA","K11424//histone-lysine N-methyltransferase NSD2 [EC:2.1.1.43]","NP_001244937.1//zinc finger CW-type PWWP domain protein 1 isoform 2 [Homo sapiens];NP_060454.3//zinc finger CW-type PWWP domain protein 1 isoform 1 [Homo sapiens]","4;1//3"]
[80818,4353,1.8,1.76,-0.0324214776923775,0.944534658766212,"*",0.898118,"ZNF436","GO:0005654//nucleoplasm;GO:0005829//cytosol","GO:0046872//metal ion binding;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated","K09230//SCAN domain-containing zinc finger protein","XP_013966140.1//zinc finger protein 436 isoform X2 [Canis lupus familiaris]","1//3;2//1"]
[10421,3448,27.22,26.62,-0.0321564955921028,0.72243266701345,"*",0.6086,"CD2BP2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005682//U5 snRNP;GO:0016607//nuclear speck;GO:0001650//fibrillar center;GO:0005737//cytoplasm","GO:0043021//ribonucleoprotein complex binding","GO:0000244//spliceosomal tri-snRNP complex assembly;GO:0000398//mRNA splicing, via spliceosome;GO:0010923//negative regulation of phosphatase activity","K13099//CD2 antigen cytoplasmic tail-binding protein 2","NP_006101.1//CD2 antigen cytoplasmic tail-binding protein 2 [Homo sapiens]","1//3;2//1"]
[3949,5177,24.51,23.97,-0.0321405752177068,0.438018759139179,"*",0.291784,"LDLR","GO:0016020//membrane;GO:0010008//endosome membrane;GO:0016323//basolateral plasma membrane;GO:0005615//extracellular space;GO:0005770//late endosome;GO:0009897//external side of plasma membrane;GO:0034362//low-density lipoprotein particle;GO:0036020//endolysosome membrane;GO:0043235//receptor complex;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0097443//sorting endosome;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005769//early endosome;GO:0036477//somatodendritic compartment;GO:0005622//intracellular;GO:0005764//lysosome;GO:0009986//cell surface;GO:1990666//PCSK9-LDLR complex;GO:0005905//clathrin-coated pit;GO:0005794//Golgi apparatus;GO:0045177//apical part of cell","GO:0002020//protease binding;GO:0032050//clathrin heavy chain binding;GO:0005041//low-density lipoprotein receptor activity;GO:0001540//amyloid-beta binding;GO:0030229//very-low-density lipoprotein particle receptor activity;GO:0030169//low-density lipoprotein particle binding;GO:0042802//identical protein binding;GO:0005509//calcium ion binding;GO:0001618//virus receptor activity","GO:0010867//positive regulation of triglyceride biosynthetic process;GO:0045807//positive regulation of endocytosis;GO:0030301//cholesterol transport;GO:0034382//chylomicron remnant clearance;GO:0061889//negative regulation of astrocyte activation;GO:1903979//negative regulation of microglial cell activation;GO:0010628//positive regulation of gene expression;GO:0090181//regulation of cholesterol metabolic process;GO:0006898//receptor-mediated endocytosis;GO:0030299//intestinal cholesterol absorption;GO:0042159//lipoprotein catabolic process;GO:2000188//regulation of cholesterol homeostasis;GO:0006629//lipid metabolic process;GO:0071404//cellular response to low-density lipoprotein particle stimulus;GO:0008203//cholesterol metabolic process;GO:0097242//amyloid-beta clearance;GO:0010899//regulation of phosphatidylcholine catabolic process;GO:0010629//negative regulation of gene expression;GO:0050729//positive regulation of inflammatory response;GO:0071398//cellular response to fatty acid;GO:0007616//long-term memory;GO:0010986//positive regulation of lipoprotein particle clearance;GO:1900223//positive regulation of amyloid-beta clearance;GO:0015914//phospholipid transport;GO:0034381//plasma lipoprotein particle clearance;GO:0090118//receptor-mediated endocytosis involved in cholesterol transport;GO:0006897//endocytosis;GO:0070508//cholesterol import;GO:0042632//cholesterol homeostasis;GO:0061771//response to caloric restriction;GO:1905907//negative regulation of amyloid fibril formation;GO:0034383//low-density lipoprotein particle clearance;GO:0051246//regulation of protein metabolic process;GO:0061024//membrane organization;GO:0051248//negative regulation of protein metabolic process;GO:1905167//positive regulation of lysosomal protein catabolic process","K12473//low-density lipoprotein receptor","BAD92646.1//low density lipoprotein receptor precursor variant, partial [Homo sapiens];NP_001182732.1//low-density lipoprotein receptor isoform 6 precursor [Homo sapiens];NP_001182729.1//low-density lipoprotein receptor isoform 4 precursor [Homo sapiens];NP_001182728.1//low-density lipoprotein receptor isoform 3 precursor [Homo sapiens]","4;1//3"]
[201163,3740,23.22,22.71,-0.0320402661586785,0.409412132834245,"*",0.267038,"FLCN","GO:0005929//cilium;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005764//lysosome;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0005085//guanyl-nucleotide exchange factor activity;GO:0032403//protein complex binding","GO:0032007//negative regulation of TOR signaling;GO:0007043//cell-cell junction assembly;GO:0010823//negative regulation of mitochondrion organization;GO:0045785//positive regulation of cell adhesion;GO:0010629//negative regulation of gene expression;GO:1901723//negative regulation of cell proliferation involved in kidney development;GO:0032008//positive regulation of TOR signaling;GO:0001932//regulation of protein phosphorylation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0043065//positive regulation of apoptotic process;GO:2001170//negative regulation of ATP biosynthetic process;GO:0001934//positive regulation of protein phosphorylation;GO:0032465//regulation of cytokinesis;GO:0051898//negative regulation of protein kinase B signaling;GO:0030097//hemopoiesis;GO:0030308//negative regulation of cell growth;GO:0031929//TOR signaling;GO:0032006//regulation of TOR signaling;GO:0035065//regulation of histone acetylation;GO:0001701//in utero embryonic development;GO:0030336//negative regulation of cell migration;GO:2000973//regulation of pro-B cell differentiation;GO:0010508//positive regulation of autophagy;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:1900181//negative regulation of protein localization to nucleus;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:2000506//negative regulation of energy homeostasis;GO:0035024//negative regulation of Rho protein signal transduction","K09594//folliculin","NP_001340158.1//folliculin isoform 3 [Homo sapiens];NP_653207.1//folliculin isoform 2 [Homo sapiens];XP_018882612.1//PREDICTED: folliculin isoform X1 [Gorilla gorilla gorilla]","6;1//3"]
[7553,2286,10.49,10.26,-0.0319839469702135,0.528680152639087,"*",0.371208,"ZNF7","GO:0005634//nucleus;GO:0005622//intracellular","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0007275//multicellular organism development;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","XP_017739070.1//PREDICTED: zinc finger protein 7 isoform X12 [Rhinopithecus bieti];XP_017739063.1//PREDICTED: zinc finger protein 7 isoform X7 [Rhinopithecus bieti];NP_001317552.1//zinc finger protein 7 isoform 5 [Homo sapiens];XP_017739068.1//PREDICTED: zinc finger protein 7 isoform X10 [Rhinopithecus bieti];XP_017739062.1//PREDICTED: zinc finger protein 7 isoform X6 [Rhinopithecus bieti];XP_017739069.1//PREDICTED: zinc finger protein 7 isoform X11 [Rhinopithecus bieti];XP_017739058.1//PREDICTED: zinc finger protein 7 isoform X2 [Rhinopithecus bieti]","1//3;3//A2MP1"]
[143282,2564,1.37,1.34,-0.0319428925027542,0.962738002744201,"*",0.922418,"FGFBP3","GO:0031012//extracellular matrix;GO:0005576//extracellular region","GO:0008201//heparin binding;GO:0017134//fibroblast growth factor binding","GO:0045743//positive regulation of fibroblast growth factor receptor signaling pathway;GO:0043117//positive regulation of vascular permeability","K13172//serine/arginine repetitive matrix protein 2","XP_007961726.1//PREDICTED: fibroblast growth factor-binding protein 3 isoform X1 [Chlorocebus sabaeus]",4]
[91010,11141,1.37,1.34,-0.0319428925027542,0.941249545196809,"*",0.893698,"FMNL3","GO:0043231//intracellular membrane-bounded organelle;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0003779//actin binding;GO:0017048//Rho GTPase binding;GO:0032794//GTPase activating protein binding","GO:0016477//cell migration;GO:0001525//angiogenesis;GO:0030036//actin cytoskeleton organization;GO:0007010//cytoskeleton organization;GO:0008360//regulation of cell shape","K05745//diaphanous 3;K04512//dishevelled associated activator of morphogenesis","NP_783863.4//formin-like protein 3 isoform 1 [Homo sapiens];NP_944489.2//formin-like protein 3 isoform 2 [Homo sapiens]","4;2//1"]
[7296,3889,281.87,275.7,-0.0319306697500869,0.0883056296377009,"*",0.0405872,"TXNRD1","GO:0070062//extracellular exosome;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005623//cell;GO:0001650//fibrillar center;GO:0005739//mitochondrion","GO:0015035//protein disulfide oxidoreductase activity;GO:0009055//electron transfer activity;GO:0050660//flavin adenine dinucleotide binding;GO:0004791//thioredoxin-disulfide reductase activity","GO:0001707//mesoderm formation;GO:0008283//cell proliferation;GO:0045454//cell redox homeostasis","K22182//thioredoxin reductase (NADPH) [EC:1.8.1.9]","XP_004373834.1//PREDICTED: thioredoxin reductase 1, cytoplasmic [Trichechus manatus latirostris];NP_001243891.1//thioredoxin reductase 1, cytoplasmic [Oryctolagus cuniculus];XP_007950590.1//PREDICTED: LOW QUALITY PROTEIN: thioredoxin reductase 1, cytoplasmic [Orycteropus afer afer]","1//3;3//A2MP1;2//1"]
[10626,2520,112.49,110.04,-0.0317687114164872,0.0301823381731835,"*",0.01193576,"TRIM16","GO:0016605//PML body;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0032089//NACHT domain binding;GO:0008270//zinc ion binding;GO:0019966//interleukin-1 binding","GO:0048386//positive regulation of retinoic acid receptor signaling pathway;GO:0050718//positive regulation of interleukin-1 beta secretion;GO:0045618//positive regulation of keratinocyte differentiation;GO:0032526//response to retinoic acid;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046683//response to organophosphorus;GO:0043966//histone H3 acetylation;GO:0043967//histone H4 acetylation;GO:0060416//response to growth hormone","K10266//F-box and WD-40 domain protein 10;K12006//tripartite motif-containing protein 16","NP_001340150.1//tripartite motif-containing protein 16-like protein isoform 3 [Homo sapiens];NP_006461.3//tripartite motif-containing protein 16 isoform a [Homo sapiens];NP_001335050.1//tripartite motif-containing protein 16 isoform b [Homo sapiens]","1//3;4"]
[153222,6359,0.46,0.45,-0.0317088597273381,1.02203968981064,"*",0.993376,"CREBRF","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0005737//cytoplasm","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding","GO:0006810//transport;GO:0034976//response to endoplasmic reticulum stress;GO:0032388//positive regulation of intracellular transport;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:1900102//negative regulation of endoplasmic reticulum unfolded protein response;GO:0045732//positive regulation of protein catabolic process;GO:1902213//positive regulation of prolactin signaling pathway;GO:0051222//positive regulation of protein transport;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0042711//maternal behavior;GO:1900170//negative regulation of glucocorticoid mediated signaling pathway","K21554//CREB3 regulatory factor","XP_017403141.1//PREDICTED: CREB3 regulatory factor-like isoform X1 [Cebus capucinus imitator];XP_004043054.2//PREDICTED: CREB3 regulatory factor isoform X1 [Gorilla gorilla gorilla]","1//3;2//1"]
[125111,4042,10.14,9.92,-0.0316456266164655,0.83273401257514,"*",0.754486,"GJD3","GO:0005922//connexin complex;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane","GO:0005216//ion channel activity;GO:0005243//gap junction channel activity","GO:0016264//gap junction assembly;GO:0009749//response to glucose;GO:0007154//cell communication","K07627//gap junction delta-3 protein","NP_689343.3//gap junction delta-3 protein [Homo sapiens]","3//A2MP1"]
[3838,2126,359.43,351.65,-0.0315706118117834,0.309643352288342,"*",0.183394,"KPNA2","GO:0016020//membrane;GO:0043657//host cell;GO:0005654//nucleoplasm;GO:0005643//nuclear pore;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0008565//protein transporter activity;GO:0042826//histone deacetylase binding;GO:0008139//nuclear localization sequence binding","GO:0019054//modulation by virus of host process;GO:0006607//NLS-bearing protein import into nucleus;GO:0075733//intracellular transport of virus;GO:0000018//regulation of DNA recombination;GO:0006259//DNA metabolic process","K15043//importin subunit alpha-2","NP_002257.1//importin subunit alpha-1 [Homo sapiens]","1//3;3//A2MP1"]
[81617,3512,0.94,0.92,-0.0310268956206244,0.959531274440518,"*",0.917964,"CAB39L","GO:0070062//extracellular exosome;GO:0005829//cytosol","NA","GO:0007050//cell cycle arrest","K08272//calcium binding protein 39","XP_011919654.1//PREDICTED: calcium-binding protein 39-like isoform X1 [Cercocebus atys]","1//3;3//A2MP1;2//1"]
[27042,8505,5.66,5.54,-0.030916076782694,0.815988302380621,"*",0.733848,"DIEXF","GO:0005654//nucleoplasm;GO:0032040//small-subunit processome;GO:0005730//nucleolus","GO:0034511//U3 snoRNA binding;GO:0003723//RNA binding;GO:0019843//rRNA binding","GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0007275//multicellular organism development;GO:0006364//rRNA processing","K14774//U3 small nucleolar RNA-associated protein 25","NP_055203.4//digestive organ expansion factor homolog [Homo sapiens]",6]
[222183,3673,3.8,3.72,-0.0306967972229166,0.936474429572808,"*",0.886526,"SRRM3","NA","NA","NA","K13172//serine/arginine repetitive matrix protein 2","NP_001103669.1//serine/arginine repetitive matrix protein 3 isoform b [Homo sapiens];NP_001278760.1//serine/arginine repetitive matrix protein 3 isoform a [Homo sapiens]","1//3;2//1"]
[283234,4932,0.95,0.93,-0.0306967972229164,0.9730965352443,"*",0.935084,"CCDC88B","GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005737//cytoplasm","GO:0051959//dynein light intermediate chain binding;GO:0008017//microtubule binding","GO:0042832//defense response to protozoan;GO:0042102//positive regulation of T cell proliferation;GO:0050870//positive regulation of T cell activation;GO:0001819//positive regulation of cytokine production;GO:0030705//cytoskeleton-dependent intracellular transport;GO:0031122//cytoplasmic microtubule organization","K16628//collagen, type VII, alpha","NP_115627.6//coiled-coil domain-containing protein 88B precursor [Homo sapiens]",5]
[254042,3129,2.86,2.8,-0.0305883198334231,0.909789144231412,"*",0.85255,"METAP1D","GO:0005739//mitochondrion","GO:0046872//metal ion binding;GO:0004177//aminopeptidase activity;GO:0008235//metalloexopeptidase activity","GO:0031365//N-terminal protein amino acid modification;GO:0018206//peptidyl-methionine modification","K01265//methionyl aminopeptidase [EC:3.4.11.18]","NP_954697.1//methionine aminopeptidase 1D, mitochondrial isoform 1 precursor [Homo sapiens];XP_003309462.1//PREDICTED: methionine aminopeptidase 1D, mitochondrial isoform X1 [Pan troglodytes];AAY55948.1//mitochondrial methionine aminopeptidase 3 [Homo sapiens]","1//3;2//1"]
[51016,931,31.48,30.82,-0.030568678992701,0.788486040458339,"*",0.69786,"EMC9","GO:0072546//ER membrane protein complex;GO:0005737//cytoplasm","NA","NA","K06697//proteasome activator subunit 2 (PA28 beta);K09291//nucleoprotein TPR","NP_057133.2//ER membrane protein complex subunit 9 isoform a [Homo sapiens];XP_007984475.1//PREDICTED: ER membrane protein complex subunit 9 isoform X1 [Chlorocebus sabaeus];XP_009209541.1//ER membrane protein complex subunit 9 isoform X1 [Papio anubis]","1//3;3//A2MP1"]
[119032,2436,7.66,7.5,-0.0304537965417138,0.835936339604438,"*",0.759376,"BORCS7","NA","NA","NA","K20821//BLOC-1 related complex subunit 7","XP_003825579.2//PREDICTED: UPF0693 protein C10orf32 homolog [Pan paniscus]","1//3;3//A2MP1"]
[84553,11498,0.96,0.94,-0.0303736490435189,0.885990500269687,"*",0.82265,"FAXC","GO:0016021//integral component of membrane","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K09239//human immunodeficiency virus type I enhancer-binding protein;K05746//enabled;K11447//histone demethylase [EC:1.14.11.-];K01064//wingless-type MMTV integration site family, member 9;K10367//formin 1","XP_015328316.1//PREDICTED: failed axon connections homolog isoform X1 [Bos taurus];XP_004862550.1//failed axon connections homolog isoform X2 [Heterocephalus glaber];EAW48486.1//chromosome 6 open reading frame 168, isoform CRA_d [Homo sapiens];XP_006055901.1//PREDICTED: failed axon connections homolog, partial [Bubalus bubalis];XP_017363172.1//PREDICTED: failed axon connections homolog isoform X1 [Cebus capucinus imitator]","1//3;3//A2MP1"]
[3728,3494,53.3,52.19,-0.0303621310260194,0.692690508438819,"*",0.575522,"JUP","NA","NA","NA","K10056//junction plakoglobin","XP_016787309.1//PREDICTED: junction plakoglobin isoform X1 [Pan troglodytes];XP_016787311.1//PREDICTED: junction plakoglobin isoform X3 [Pan troglodytes];XP_016787310.1//PREDICTED: junction plakoglobin isoform X2 [Pan troglodytes];AAH00441.2//JUP protein, partial [Homo sapiens]","1//3;3//A2MP1"]
[54751,2893,29.89,29.27,-0.030240151269344,0.633720315544472,"*",0.477254,"FBLIM1","GO:0001725//stress fiber;GO:0005925//focal adhesion;GO:0005938//cell cortex;GO:0005829//cytosol;GO:0001650//fibrillar center;GO:0030054//cell junction","GO:0046872//metal ion binding;GO:0031005//filamin binding","GO:0098609//cell-cell adhesion;GO:0033623//regulation of integrin activation;GO:0034329//cell junction assembly;GO:0008360//regulation of cell shape","K10447//kelch-like protein 9/13;K06273//zyxin","NP_060026.2//filamin-binding LIM protein 1 isoform a [Homo sapiens];NP_001019386.1//filamin-binding LIM protein 1 isoform b [Homo sapiens];NP_001019387.1//filamin-binding LIM protein 1 isoform c [Homo sapiens]","1//3;3//A2MP1;2//1"]
[84572,1255,18.83,18.44,-0.03019434418489,0.884228042099582,"*",0.82046,"GNPTG","GO:0070062//extracellular exosome;GO:0005794//Golgi apparatus;GO:0000139//Golgi membrane","GO:0003976//UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity;GO:0042803//protein homodimerization activity","GO:0016256//N-glycan processing to lysosome;GO:0046835//carbohydrate phosphorylation","K10087//N-acetylglucosamine-1-phosphate transferase, gamma subunit","NP_115909.1//N-acetylglucosamine-1-phosphotransferase subunit gamma precursor [Homo sapiens]",4]
[51271,2814,38.63,37.83,-0.0301909011825554,0.799048777292576,"*",0.71021,"UBAP1","GO:0043657//host cell;GO:0010008//endosome membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0000813//ESCRT I complex;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0043130//ubiquitin binding","GO:0016197//endosomal transport;GO:0075733//intracellular transport of virus;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0015031//protein transport;GO:0019058//viral life cycle","K22069//LYR motif-containing protein 4;K09228//KRAB domain-containing zinc finger protein;K05632//atrophin-1 interacting protein 4 [EC:2.3.2.26];K02159//apoptosis regulator BAX;K10477//BTB/POZ domain-containing protein 1/2","NP_001164672.1//ubiquitin-associated protein 1 isoform 2 [Homo sapiens];NP_057609.2//ubiquitin-associated protein 1 isoform 1 [Homo sapiens];NP_001164673.1//ubiquitin-associated protein 1 isoform 3 [Homo sapiens]","4;1//3;2//1"]
[63827,2998,2.92,2.86,-0.0299532221016278,0.822909415440156,"*",0.74203,"BCAN","GO:0043202//lysosomal lumen;GO:0005576//extracellular region;GO:0031225//anchored component of membrane;GO:0005578//proteinaceous extracellular matrix;GO:0005796//Golgi lumen","GO:0005201//extracellular matrix structural constituent;GO:0030246//carbohydrate binding;GO:0005540//hyaluronic acid binding","GO:0021766//hippocampus development;GO:0030208//dermatan sulfate biosynthetic process;GO:0030206//chondroitin sulfate biosynthetic process;GO:0007417//central nervous system development;GO:0022617//extracellular matrix disassembly;GO:0007155//cell adhesion;GO:0030198//extracellular matrix organization;GO:0030207//chondroitin sulfate catabolic process;GO:0001501//skeletal system development;GO:0030203//glycosaminoglycan metabolic process","K06795//brevican","NP_940819.1//brevican core protein isoform 2 precursor [Homo sapiens];XP_016857536.1//PREDICTED: brevican core protein isoform X1 [Homo sapiens]","4;1//3"]
[501,4953,9.8,9.6,-0.0297473433940522,0.834155859954423,"*",0.756192,"ALDH7A1","GO:0005759//mitochondrial matrix;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005739//mitochondrion","GO:0016491//oxidoreductase activity;GO:0004043//L-aminoadipate-semialdehyde dehydrogenase activity;GO:0008802//betaine-aldehyde dehydrogenase activity;GO:0004029//aldehyde dehydrogenase (NAD) activity","GO:0006081//cellular aldehyde metabolic process;GO:0019285//glycine betaine biosynthetic process from choline;GO:0007605//sensory perception of sound;GO:0006554//lysine catabolic process;GO:0042426//choline catabolic process","K14085//aldehyde dehydrogenase family 7 member A1 [EC:1.2.1.31 1.2.1.8 1.2.1.3]","XP_001157473.3//PREDICTED: alpha-aminoadipic semialdehyde dehydrogenase [Pan troglodytes];XP_011945494.1//PREDICTED: alpha-aminoadipic semialdehyde dehydrogenase [Cercocebus atys]","4;1//3"]
[92745,1993,0.49,0.48,-0.0297473433940521,1.0206330629891,"*",0.996098,"SLC38A5","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0015187//glycine transmembrane transporter activity;GO:0015171//amino acid transmembrane transporter activity","GO:0006865//amino acid transport","K14992//solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 5","XP_005272752.3//PREDICTED: sodium-coupled neutral amino acid transporter 5 isoform X2 [Homo sapiens]","3//A2MP1"]
[55096,1679,0.49,0.48,-0.0297473433940521,1.02010826020637,"*",0.996416,"EBLN2","NA","NA","NA","NA","NP_060499.3//endogenous Bornavirus-like nucleoprotein 2 [Homo sapiens]",4]
[266747,2988,0.98,0.96,-0.0297473433940521,1.02197386642623,"*",0.993376,"RGL4","GO:0031410//cytoplasmic vesicle;GO:0005622//intracellular","GO:0005085//guanyl-nucleotide exchange factor activity","GO:0007264//small GTPase mediated signal transduction","K08732//ral guanine nucleotide dissociation stimulator","EAW59595.1//Ral-GDS related protein Rgr, isoform CRA_b [Homo sapiens];NP_705843.1//ral-GDS-related protein isoform 2 precursor [Homo sapiens];NP_001316353.1//ral-GDS-related protein isoform 1 precursor [Homo sapiens]","1//3"]
[57147,2990,2.46,2.41,-0.0296251691092782,1.01999200593663,"*",0.989534,"SCYL3","GO:0005794//Golgi apparatus;GO:0030027//lamellipodium;GO:0005737//cytoplasm","GO:0005524//ATP binding;GO:0004672//protein kinase activity","GO:0016477//cell migration;GO:0006468//protein phosphorylation","K17542//SCY1-like protein 3","XP_003893591.2//protein-associating with the carboxyl-terminal domain of ezrin isoform X1 [Papio anubis];XP_003893590.2//protein-associating with the carboxyl-terminal domain of ezrin isoform X2 [Papio anubis]","6;3//A2MP1"]
[57617,3922,13.79,13.51,-0.0295947821882958,0.813172189984656,"*",0.72989,"VPS18","GO:0005765//lysosomal membrane;GO:0005770//late endosome;GO:0030136//clathrin-coated vesicle;GO:0031902//late endosome membrane;GO:0005764//lysosome;GO:0005768//endosome;GO:0005884//actin filament;GO:0030897//HOPS complex;GO:0030123//AP-3 adaptor complex;GO:0005776//autophagosome;GO:0005769//early endosome;GO:0033263//CORVET complex","GO:0003779//actin binding;GO:0046872//metal ion binding;GO:0030674//protein binding, bridging;GO:0019905//syntaxin binding","GO:0006904//vesicle docking involved in exocytosis;GO:0016192//vesicle-mediated transport;GO:0006886//intracellular protein transport;GO:0006914//autophagy;GO:0008333//endosome to lysosome transport;GO:0007032//endosome organization;GO:0035542//regulation of SNARE complex assembly;GO:0007040//lysosome organization;GO:0046718//viral entry into host cell","K20181//vacuolar protein sorting-associated protein 18","NP_065908.1//vacuolar protein sorting-associated protein 18 homolog [Homo sapiens]","2//1"]
[10130,2349,146.8,143.84,-0.0293870422161279,0.555478221411192,"*",0.400178,"PDIA6","GO:0070062//extracellular exosome;GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0042470//melanosome;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0034663//endoplasmic reticulum chaperone complex;GO:0005829//cytosol;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane","GO:0003756//protein disulfide isomerase activity;GO:0015037//peptide disulfide oxidoreductase activity","GO:0006457//protein folding;GO:0043687//post-translational protein modification;GO:0034976//response to endoplasmic reticulum stress;GO:0030168//platelet activation;GO:0043277//apoptotic cell clearance;GO:0045454//cell redox homeostasis;GO:0044267//cellular protein metabolic process;GO:0036498//IRE1-mediated unfolded protein response;GO:0070527//platelet aggregation","K09584//protein disulfide-isomerase A6 [EC:5.3.4.1]","NP_001269634.1//protein disulfide-isomerase A6 isoform b [Homo sapiens];NP_005733.1//protein disulfide-isomerase A6 isoform d precursor [Homo sapiens];NP_001269633.1//protein disulfide-isomerase A6 isoform a [Homo sapiens];NP_001269636.1//protein disulfide-isomerase A6 isoform e precursor [Homo sapiens]","1//3;3//A2MP1"]
[79654,3628,10.92,10.7,-0.0293620596313432,0.847592577698532,"*",0.773732,"HECTD3","GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm","GO:0061630//ubiquitin protein ligase activity;GO:0019905//syntaxin binding;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity","GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process","K12233//E3 ubiquitin-protein ligase HECTD3 [EC:2.3.2.26]","XP_017737303.1//PREDICTED: E3 ubiquitin-protein ligase HECTD3 [Rhinopithecus bieti]",5]
[752,3973,17.94,17.58,-0.0292448197758575,0.789859668739401,"*",0.699768,"FMNL1","GO:0045335//phagocytic vesicle;GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005938//cell cortex;GO:0032059//bleb;GO:0005829//cytosol;GO:0005886//plasma membrane","GO:0051015//actin filament binding;GO:0005522//profilin binding;GO:0048365//Rac GTPase binding;GO:0032794//GTPase activating protein binding","GO:0006929//substrate-dependent cell migration;GO:0030866//cortical actin cytoskeleton organization;GO:0008360//regulation of cell shape;GO:0051014//actin filament severing","K04512//dishevelled associated activator of morphogenesis;K05741//diaphanous 2","NP_005883.2//formin-like protein 1 [Homo sapiens]","3//A2MP1"]
[374868,4467,5.49,5.38,-0.0291999764485746,0.889731479033452,"*",0.827516,"ATP9B","GO:0005768//endosome;GO:0016021//integral component of membrane;GO:0005802//trans-Golgi network;GO:0005886//plasma membrane;GO:0048471//perinuclear region of cytoplasm","GO:0000287//magnesium ion binding;GO:0005524//ATP binding;GO:0004012//phospholipid-translocating ATPase activity","GO:0045332//phospholipid translocation;GO:0006897//endocytosis;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER","K01530//phospholipid-translocating ATPase [EC:3.6.3.1]","XP_009250766.1//PREDICTED: probable phospholipid-transporting ATPase IIB isoform X1 [Pongo abelii]","4;1//3"]
[84627,13203,6.99,6.85,-0.0291884675275474,0.765333924585219,"*",0.667068,"ZNF469","NA","GO:0046872//metal ion binding;GO:0003676//nucleic acid binding","NA","K22020//mucin-19","NP_001120936.2//zinc finger protein 469 [Homo sapiens]","2//1"]
[146434,5516,0.5,0.49,-0.0291463456595165,0.954437598793759,"*",0.911418,"ZNF597","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","XP_004438190.1//PREDICTED: zinc finger protein 597 isoform X1 [Ceratotherium simum simum]","2//1"]
[5924,8171,0.5,0.49,-0.0291463456595165,0.968066708330615,"*",0.928978,"RASGRF2","GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane","GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005516//calmodulin binding;GO:0005089//Rho guanyl-nucleotide exchange factor activity","GO:0043065//positive regulation of apoptotic process;GO:0000165//MAPK cascade;GO:0007264//small GTPase mediated signal transduction;GO:0034976//response to endoplasmic reticulum stress;GO:0035023//regulation of Rho protein signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction","K12326//Ras-specific guanine nucleotide-releasing factor 2","NP_008840.1//ras-specific guanine nucleotide-releasing factor 2 [Homo sapiens]","2//1"]
[199953,3873,11.55,11.32,-0.0290188934715377,0.860483699543317,"*",0.790294,"TMEM201","GO:0000922//spindle pole;GO:0005635//nuclear envelope;GO:0005639//integral component of nuclear inner membrane;GO:0005737//cytoplasm","GO:0051015//actin filament binding;GO:0005521//lamin binding","GO:0051642//centrosome localization;GO:0090435//protein localization to nuclear envelope;GO:0007097//nuclear migration;GO:0006998//nuclear envelope organization;GO:0010761//fibroblast migration","K10955//mucin-2;K22020//mucin-19;K13908//mucin-5B","NP_001124396.2//transmembrane protein 201 isoform 1 [Homo sapiens];NP_001010866.1//transmembrane protein 201 isoform 2 [Homo sapiens]","3//A2MP1;2//1"]
[81794,3434,10.05,9.85,-0.0289998717225525,0.755216311268317,"*",0.65494,"ADAMTS10","GO:0031012//extracellular matrix;GO:0001527//microfibril;GO:0005578//proteinaceous extracellular matrix","GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding","GO:0007229//integrin-mediated signaling pathway","K08625//a disintegrin and metalloproteinase with thrombospondin motifs 10 [EC:3.4.24.-]","XP_014197944.1//PREDICTED: A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X1 [Pan paniscus];NP_001269281.1//A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[10868,4538,2.02,1.98,-0.0288548626721851,0.870849811787072,"*",0.802922,"USP20","GO:0005829//cytosol;GO:0005813//centrosome;GO:0048471//perinuclear region of cytoplasm","GO:0004843//thiol-dependent ubiquitin-specific protease activity;GO:0001664//G-protein coupled receptor binding;GO:0004197//cysteine-type endopeptidase activity;GO:0008270//zinc ion binding;GO:0036459//thiol-dependent ubiquitinyl hydrolase activity","GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0071108//protein K48-linked deubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination;GO:0006897//endocytosis;GO:0070536//protein K63-linked deubiquitination","K11848//ubiquitin carboxyl-terminal hydrolase 20/33 [EC:3.4.19.12]","NP_001103773.2//ubiquitin carboxyl-terminal hydrolase 20 [Homo sapiens]","4;3//A2MP1;7"]
[4324,4268,9.6,9.41,-0.0288396828799817,0.850796923371648,"*",0.778468,"MMP15","GO:0031012//extracellular matrix;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane","GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding;GO:0008047//enzyme activator activity;GO:0070006//metalloaminopeptidase activity","GO:0022617//extracellular matrix disassembly;GO:0032355//response to estradiol;GO:0006508//proteolysis;GO:0006464//cellular protein modification process;GO:0035987//endodermal cell differentiation;GO:0030574//collagen catabolic process","K07995//matrix metalloproteinase-15 (membrane-inserted) [EC:3.4.24.-]","NP_002419.1//matrix metalloproteinase-15 preproprotein [Homo sapiens]","3//A2MP1"]
[112942,1324,25.43,24.93,-0.0286485791986055,0.869353521559041,"*",0.801488,"CFAP36","GO:0005634//nucleus;GO:0042995//cell projection;GO:0005737//cytoplasm","NA","NA","K16742//ADP-ribosylation factor-like protein 2-binding protein","NP_001269690.1//cilia- and flagella-associated protein 36 isoform a [Homo sapiens];NP_542398.3//cilia- and flagella-associated protein 36 isoform b [Homo sapiens]","6;1//3"]
[28511,2352,55.11,54.03,-0.0285534452050735,0.647349116859122,"*",0.526422,"NKIRAS2","GO:0016020//membrane;GO:0005622//intracellular;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0002039//p53 binding;GO:0008270//zinc ion binding;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:0007165//signal transduction;GO:0007249//I-kappaB kinase/NF-kappaB signaling","K17197//NF-kappa-B inhibitor-interacting Ras-like protein","OWK15227.1//NKIRAS2 [Cervus elaphus hippelaphus];NP_001138400.1//NF-kappa-B inhibitor-interacting Ras-like protein 2 isoform b [Homo sapiens];NP_060065.2//NF-kappa-B inhibitor-interacting Ras-like protein 2 isoform a [Homo sapiens]","1//3;2//1;5"]
[51421,5003,24.08,23.61,-0.0284373505310595,0.736766675767918,"*",0.635158,"AMOTL2","GO:0016324//apical plasma membrane;GO:0005829//cytosol;GO:0005923//bicellular tight junction;GO:0055037//recycling endosome","GO:0042802//identical protein binding","GO:0035329//hippo signaling;GO:0016055//Wnt signaling pathway","K06104//angiomotin like","NP_001265612.1//angiomotin-like protein 2 isoform 1 [Homo sapiens];BAD97318.1//Angiomotin like 2 (Fragment) variant, partial [Homo sapiens]","1//3;3//A2MP1"]
[378,1758,80.84,79.27,-0.0282943453228974,0.718865672175078,"*",0.60456,"ARF4","NA","NA","NA","K07939//ADP-ribosylation factor 4","ELK07801.1//ADP-ribosylation factor 4 [Pteropus alecto]","3//A2MP1"]
[25841,4919,8.8,8.63,-0.0281429643457046,0.857430989686497,"*",0.78588,"ABTB2","NA","NA","NA","K10521//ankyrin repeat and BTB/POZ domain-containing protein 2","EAW68173.1//ankyrin repeat and BTB (POZ) domain containing 2, isoform CRA_b [Homo sapiens]","2//1"]
[2760,3675,17.2,16.87,-0.0279485913018944,0.612417594088504,"*",0.456572,"GM2A","GO:0070062//extracellular exosome;GO:0045179//apical cortex;GO:0035578//azurophil granule lumen;GO:0043202//lysosomal lumen;GO:0005576//extracellular region;GO:0009898//cytoplasmic side of plasma membrane;GO:0005739//mitochondrion;GO:0005889//hydrogen:potassium-exchanging ATPase complex","GO:0005319//lipid transporter activity;GO:0004563//beta-N-acetylhexosaminidase activity;GO:0016004//phospholipase activator activity;GO:0030290//sphingolipid activator protein activity;GO:0008047//enzyme activator activity;GO:0032428//beta-N-acetylgalactosaminidase activity","GO:0051345//positive regulation of hydrolase activity;GO:0006687//glycosphingolipid metabolic process;GO:0009313//oligosaccharide catabolic process;GO:0019915//lipid storage;GO:0043312//neutrophil degranulation;GO:0050885//neuromuscular process controlling balance;GO:0006689//ganglioside catabolic process;GO:0007611//learning or memory","K12383//ganglioside GM2 activator","CAA43408.1//GM2-activator protein, partial [Homo sapiens];NP_001161079.1//ganglioside GM2 activator isoform 2 precursor [Homo sapiens]","4;1//3"]
[2055,7185,4.17,4.09,-0.0279465405029148,0.883441687124435,"*",0.819122,"CLN8","GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005789//endoplasmic reticulum membrane","NA","GO:0007399//nervous system development;GO:0045861//negative regulation of proteolysis;GO:0008203//cholesterol metabolic process;GO:0006869//lipid transport;GO:0030163//protein catabolic process;GO:0006672//ceramide metabolic process;GO:0006644//phospholipid metabolic process;GO:0046513//ceramide biosynthetic process;GO:0008610//lipid biosynthetic process","K12360//ceroid-lipofuscinosis neuronal protein 8","AAI36826.1//Ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) [Homo sapiens]","3//A2MP1"]
[55819,2272,20.36,19.97,-0.0279032286317228,0.845740229050663,"*",0.770188,"RNF130","NA","NA","NA","K15701//E3 ubiquitin-protein ligase RNF130 [EC:2.3.2.27]","XP_008013728.1//PREDICTED: E3 ubiquitin-protein ligase RNF130 isoform X3 [Chlorocebus sabaeus];XP_008013726.1//PREDICTED: E3 ubiquitin-protein ligase RNF130 isoform X1 [Chlorocebus sabaeus]","1//3;5"]
[56905,4443,28.23,27.69,-0.0278640750827626,0.73362160279761,"*",0.63038,"C15orf39","GO:0005829//cytosol","NA","NA","K10955//mucin-2;K09993//cyclin-dependent kinase inhibitor 1C","NP_056307.2//uncharacterized protein C15orf39 [Homo sapiens]",4]
[9662,5760,1.57,1.54,-0.0278342081967255,0.950691723313407,"*",0.905996,"CEP135","GO:0005814//centriole;GO:0005829//cytosol;GO:0005813//centrosome","GO:0008022//protein C-terminus binding","GO:0010389//regulation of G2/M transition of mitotic cell cycle;GO:1902857//positive regulation of non-motile cilium assembly;GO:0097711//ciliary basal body-plasma membrane docking;GO:0007099//centriole replication;GO:0000086//G2/M transition of mitotic cell cycle;GO:0010457//centriole-centriole cohesion","K16461//centrosomal protein CEP135","NP_079285.2//centrosomal protein of 135 kDa [Homo sapiens]",4]
[78987,2546,5.25,5.15,-0.0277449904829042,0.733780025641026,"*",0.630608,"CRELD1","GO:0016021//integral component of membrane","GO:0005509//calcium ion binding","GO:0003197//endocardial cushion development;GO:0003279//cardiac septum development","K08023//latent transforming growth factor beta binding protein 2/3/4;K17675//ATP-dependent RNA helicase SUPV3L1/SUV3 [EC:3.6.4.13]","NP_001026887.1//cysteine-rich with EGF-like domain protein 1 isoform 1 precursor [Homo sapiens];XP_001150237.2//PREDICTED: cysteine-rich with EGF-like domain protein 1 isoform X1 [Pan troglodytes]","4;3//A2MP1;2//1"]
[2107,3714,55.75,54.69,-0.0276947429347391,0.501231632951367,"*",0.347762,"ETF1","GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0008079//translation termination factor activity;GO:0043022//ribosome binding;GO:0003723//RNA binding;GO:1990825//sequence-specific mRNA binding;GO:0003747//translation release factor activity","GO:0006449//regulation of translational termination;GO:0006415//translational termination;GO:0006479//protein methylation;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0016032//viral process","K03265//peptide chain release factor subunit 1","XP_003215303.2//PREDICTED: eukaryotic peptide chain release factor subunit 1 [Anolis carolinensis];XP_014440263.1//PREDICTED: eukaryotic peptide chain release factor subunit 1 isoform X1 [Tupaia chinensis];NP_001269114.1//eukaryotic peptide chain release factor subunit 1 isoform 3 [Homo sapiens];XP_013204962.1//PREDICTED: eukaryotic peptide chain release factor subunit 1 isoform X1 [Microtus ochrogaster];XP_006204645.1//PREDICTED: eukaryotic peptide chain release factor subunit 1 [Vicugna pacos]","1//3;3//A2MP1"]
[41,3873,5.82,5.71,-0.0275284075454411,0.883106413182954,"*",0.81859,"ASIC1","GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0045202//synapse;GO:0005886//plasma membrane","GO:0022839//ion gated channel activity;GO:0044736//acid-sensing ion channel activity;GO:0015280//ligand-gated sodium channel activity","GO:0006810//transport;GO:0070588//calcium ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0007165//signal transduction;GO:0009268//response to pH;GO:0034220//ion transmembrane transport;GO:0071467//cellular response to pH;GO:0007613//memory;GO:0010447//response to acidic pH;GO:0008306//associative learning;GO:0006814//sodium ion transport;GO:0050915//sensory perception of sour taste;GO:0046929//negative regulation of neurotransmitter secretion;GO:0070207//protein homotrimerization;GO:0042391//regulation of membrane potential","K04829//acid-sensing ion channel 1","NP_001243759.1//acid-sensing ion channel 1 isoform c [Homo sapiens];NP_064423.2//acid-sensing ion channel 1 isoform a [Homo sapiens];XP_004778896.1//PREDICTED: acid-sensing ion channel 1 isoform X3 [Mustela putorius furo]","1//3;3//A2MP1"]
[79863,5679,6.92,6.79,-0.0273604633919929,0.866364169952413,"*",0.79781,"RBFA","GO:0005739//mitochondrion","NA","GO:0006364//rRNA processing","NA","NP_001165438.1//putative ribosome-binding factor A, mitochondrial isoform 2 precursor [Homo sapiens];NP_079081.2//putative ribosome-binding factor A, mitochondrial isoform 1 precursor [Homo sapiens]","1//3;2//1"]
[11253,2787,22.94,22.51,-0.0272993345616693,0.817544319443478,"*",0.735708,"MAN1B1","GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:1903561//extracellular vesicle;GO:0044322//endoplasmic reticulum quality control compartment;GO:0000139//Golgi membrane","GO:0004571//mannosyl-oligosaccharide 1,2-alpha-mannosidase activity;GO:0005509//calcium ion binding","GO:0006486//protein glycosylation;GO:0036508//protein alpha-1,2-demannosylation;GO:1904380//endoplasmic reticulum mannose trimming;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0036511//trimming of first mannose on A branch;GO:0006491//N-glycan processing;GO:1904382//mannose trimming involved in glycoprotein ERAD pathway;GO:0036512//trimming of second mannose on A branch;GO:0009311//oligosaccharide metabolic process;GO:0036510//trimming of terminal mannose on C branch;GO:0036509//trimming of terminal mannose on B branch","K01230//mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]","NP_057303.2//endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase [Homo sapiens]",4]
[5094,3163,176.82,173.51,-0.0272626534364785,0.469193406022654,"*",0.318954,"PCBP2","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005925//focal adhesion;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030529//intracellular ribonucleoprotein complex","GO:0003723//RNA binding;GO:0003677//DNA binding;GO:1990829//C-rich single-stranded DNA binding;GO:0031625//ubiquitin protein ligase binding;GO:0019899//enzyme binding","GO:0016070//RNA metabolic process;GO:0075522//IRES-dependent viral translational initiation;GO:0000398//mRNA splicing, via spliceosome;GO:0051607//defense response to virus;GO:0050687//negative regulation of defense response to virus;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0039694//viral RNA genome replication;GO:0016071//mRNA metabolic process;GO:0032480//negative regulation of type I interferon production;GO:0045087//innate immune response","K13162//poly(rC)-binding protein 2","NP_001122385.1//poly(rC)-binding protein 2 isoform f [Homo sapiens];BAD92062.1//poly(rC)-binding protein 2 isoform b variant, partial [Homo sapiens];NP_001122386.1//poly(rC)-binding protein 2 isoform g [Homo sapiens]","4;1//3;2//1;5"]
[10910,1810,12.87,12.63,-0.0271574144331494,0.884287702584171,"*",0.82046,"SUGT1","GO:0005634//nucleus;GO:0000151//ubiquitin ligase complex;GO:0043234//protein complex;GO:0005829//cytosol;GO:0000776//kinetochore","NA","GO:0000278//mitotic cell cycle;GO:0043947//positive regulation by host of symbiont catalytic activity;GO:0031647//regulation of protein stability","K12795//suppressor of G2 allele of SKP1","NP_001307760.1//protein SGT1 homolog isoform C [Homo sapiens];NP_006695.1//protein SGT1 homolog isoform A [Homo sapiens];NP_001124384.1//protein SGT1 homolog isoform B [Homo sapiens]","1//3;4;2//1"]
[1462,4193,5.37,5.27,-0.0271191263481981,{"v":6.74860867106796e-07,"d":"6.75E-07"},"*",{"v":1.087872E-7,"d":"1.09E-07"},"VCAN","GO:0016020//membrane;GO:0031012//extracellular matrix;GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0005578//proteinaceous extracellular matrix;GO:0005796//Golgi lumen;GO:0005576//extracellular region;GO:0043202//lysosomal lumen","GO:0005201//extracellular matrix structural constituent;GO:0030246//carbohydrate binding;GO:0005509//calcium ion binding;GO:0005539//glycosaminoglycan binding;GO:0005540//hyaluronic acid binding","GO:0043687//post-translational protein modification;GO:0001649//osteoblast differentiation;GO:0030208//dermatan sulfate biosynthetic process;GO:0030206//chondroitin sulfate biosynthetic process;GO:0007417//central nervous system development;GO:0044267//cellular protein metabolic process;GO:0007155//cell adhesion;GO:0008347//glial cell migration;GO:0030198//extracellular matrix organization;GO:0007275//multicellular organism development;GO:0030207//chondroitin sulfate catabolic process;GO:0008037//cell recognition;GO:0001501//skeletal system development;GO:0030203//glycosaminoglycan metabolic process","K06793//versican core protein","NP_001157569.1//versican core protein isoform 3 precursor [Homo sapiens];NP_001157570.1//versican core protein isoform 4 precursor [Homo sapiens];NP_001119808.1//versican core protein isoform 2 precursor [Homo sapiens];BAD92728.1//chondroitin sulfate proteoglycan 2 (versican) variant, partial [Homo sapiens]","4;1//3;2//1"]
[10956,2771,50.68,49.74,-0.0270100169239029,0.458892148010758,"*",0.309768,"OS9","GO:0005788//endoplasmic reticulum lumen;GO:0000836//Hrd1p ubiquitin ligase complex;GO:0005789//endoplasmic reticulum membrane;GO:0044322//endoplasmic reticulum quality control compartment","GO:0002020//protease binding;GO:0030246//carbohydrate binding","GO:0006605//protein targeting;GO:0030970//retrograde protein transport, ER to cytosol;GO:0055085//transmembrane transport;GO:1904380//endoplasmic reticulum mannose trimming;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0034976//response to endoplasmic reticulum stress;GO:0016567//protein ubiquitination;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0006621//protein retention in ER lumen;GO:1904153//negative regulation of retrograde protein transport, ER to cytosol","K10088//protein OS-9","NP_001017957.1//protein OS-9 isoform 3 precursor [Homo sapiens];NP_001248351.1//protein OS-9 isoform 7 precursor [Homo sapiens];NP_001248352.1//protein OS-9 isoform 8 precursor [Homo sapiens];NP_001248349.1//protein OS-9 isoform 5 precursor [Homo sapiens];NP_001248350.1//protein OS-9 isoform 6 precursor [Homo sapiens];NP_006803.1//protein OS-9 isoform 1 precursor [Homo sapiens];NP_001017956.1//protein OS-9 isoform 2 precursor [Homo sapiens];NP_001017958.1//protein OS-9 isoform 4 precursor [Homo sapiens]","1//3;3//A2MP1;2//1"]
[7170,3170,183.74,180.35,-0.0268663106711749,0.121210910949663,"*",0.0584884,"TPM3","GO:0005856//cytoskeleton;GO:0070062//extracellular exosome;GO:0005884//actin filament;GO:0001725//stress fiber;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0005862//muscle thin filament tropomyosin","GO:0051015//actin filament binding;GO:0008307//structural constituent of muscle","GO:0006928//movement of cell or subcellular component;GO:0007015//actin filament organization;GO:0030049//muscle filament sliding;GO:0006936//muscle contraction","K09290//tropomyosin 3","XP_007186605.1//PREDICTED: tropomyosin alpha-3 chain-like isoform X2 [Balaenoptera acutorostrata scammoni];NP_001036817.1//tropomyosin alpha-3 chain isoform Tpm3.7cy [Homo sapiens];NP_001036818.1//tropomyosin alpha-3 chain isoform Tpm3.4cy [Homo sapiens];XP_007186604.1//PREDICTED: tropomyosin alpha-3 chain-like isoform X1 [Balaenoptera acutorostrata scammoni];XP_021052495.1//tropomyosin alpha-3 chain isoform X9 [Mus pahari];XP_008853322.1//PREDICTED: tropomyosin alpha-3 chain isoform X11 [Nannospalax galili];NP_001036816.1//tropomyosin alpha-3 chain isoform Tpm3.2cy [Homo sapiens];XP_017650578.1//PREDICTED: tropomyosin alpha-3 chain isoform X2 [Nannospalax galili];XP_008853313.1//PREDICTED: tropomyosin alpha-3 chain isoform X12 [Nannospalax galili]","1//3;3//A2MP1"]
[9647,5199,11.97,11.75,-0.0267623954911399,0.830455834900443,"*",0.751954,"PPM1F","GO:0043234//protein complex;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm","GO:0046872//metal ion binding;GO:0004722//protein serine/threonine phosphatase activity;GO:0016791//phosphatase activity;GO:0033192//calmodulin-dependent protein phosphatase activity","GO:0035690//cellular response to drug;GO:0016576//histone dephosphorylation;GO:0010634//positive regulation of epithelial cell migration;GO:0035970//peptidyl-threonine dephosphorylation;GO:0097193//intrinsic apoptotic signaling pathway;GO:0010811//positive regulation of cell-substrate adhesion;GO:0045927//positive regulation of growth;GO:0045892//negative regulation of transcription, DNA-templated;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0051894//positive regulation of focal adhesion assembly;GO:0010628//positive regulation of gene expression;GO:0006469//negative regulation of protein kinase activity;GO:0051496//positive regulation of stress fiber assembly;GO:0050921//positive regulation of chemotaxis;GO:0044387//negative regulation of protein kinase activity by regulation of protein phosphorylation","K17502//protein phosphatase 1F [EC:3.1.3.16]","NP_055449.1//protein phosphatase 1F [Homo sapiens]","3//A2MP1"]
[84811,2216,10.34,10.15,-0.0267564582423959,0.909171180919294,"*",0.851914,"BUD13","GO:0005634//nucleus;GO:0070274//RES complex","GO:0003723//RNA binding","GO:0006406//mRNA export from nucleus;GO:0000398//mRNA splicing, via spliceosome","K13106//pre-mRNA-splicing factor CWC26","NP_116114.1//BUD13 homolog isoform 1 [Homo sapiens];NP_001153208.1//BUD13 homolog isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[1856,3046,28.35,27.83,-0.026707826497984,0.789413630812721,"*",0.699274,"DVL2","NA","NA","NA","K02353//segment polarity protein dishevelled","XP_003810156.1//PREDICTED: segment polarity protein dishevelled homolog DVL-2 isoform X1 [Pan paniscus]","2//1"]
[57019,2184,33.92,33.3,-0.0266139926045749,0.891469515265635,"*",0.829858,"CIAPIN1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005758//mitochondrial intermembrane space;GO:0005739//mitochondrion;GO:0005737//cytoplasm","GO:0009055//electron transfer activity;GO:0046872//metal ion binding;GO:0051537//2 iron, 2 sulfur cluster binding;GO:0008168//methyltransferase activity;GO:0051536//iron-sulfur cluster binding","GO:0016226//iron-sulfur cluster assembly;GO:0043066//negative regulation of apoptotic process;GO:0030097//hemopoiesis;GO:0006915//apoptotic process","NA","NP_001295287.1//anamorsin isoform 3 [Homo sapiens];NP_001295276.1//anamorsin isoform 2 [Homo sapiens];NP_064709.2//anamorsin isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[3654,3444,150.99,148.25,-0.0264208988973299,0.586587301825627,"*",0.430448,"IRAK1","GO:0010008//endosome membrane;GO:0005634//nucleus;GO:0005811//lipid droplet;GO:0045323//interleukin-1 receptor complex;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0031072//heat shock protein binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0004704//NF-kappaB-inducing kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004672//protein kinase activity","GO:0060337//type I interferon signaling pathway;GO:0032481//positive regulation of type I interferon production;GO:0070498//interleukin-1-mediated signaling pathway;GO:0034134//toll-like receptor 2 signaling pathway;GO:0001959//regulation of cytokine-mediated signaling pathway;GO:0070555//response to interleukin-1;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0051259//protein oligomerization;GO:0007165//signal transduction;GO:0070423//nucleotide-binding oligomerization domain containing signaling pathway;GO:0006468//protein phosphorylation;GO:0007250//activation of NF-kappaB-inducing kinase activity;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0046777//protein autophosphorylation;GO:0071456//cellular response to hypoxia;GO:0032496//response to lipopolysaccharide;GO:0035556//intracellular signal transduction;GO:0045893//positive regulation of transcription, DNA-templated;GO:0034162//toll-like receptor 9 signaling pathway;GO:0034142//toll-like receptor 4 signaling pathway;GO:0000187//activation of MAPK activity;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0043406//positive regulation of MAP kinase activity;GO:0034605//cellular response to heat;GO:0002224//toll-like receptor signaling pathway;GO:0007254//JNK cascade;GO:0007568//aging;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0002755//MyD88-dependent toll-like receptor signaling pathway","K04730//interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]","NP_001020414.1//interleukin-1 receptor-associated kinase 1 isoform 3 [Homo sapiens];NP_001560.2//interleukin-1 receptor-associated kinase 1 isoform 1 [Homo sapiens];NP_001020413.1//interleukin-1 receptor-associated kinase 1 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[4125,3231,13.81,13.56,-0.026356141121707,0.859533209327697,"*",0.789152,"MAN2B1","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0035578//azurophil granule lumen;GO:0043202//lysosomal lumen;GO:0005576//extracellular region","GO:0046872//metal ion binding;GO:0030246//carbohydrate binding;GO:0004559//alpha-mannosidase activity","GO:0009313//oligosaccharide catabolic process;GO:0006013//mannose metabolic process;GO:0006464//cellular protein modification process;GO:0043312//neutrophil degranulation;GO:0006517//protein deglycosylation","K12311//lysosomal alpha-mannosidase [EC:3.2.1.24]","NP_000519.2//lysosomal alpha-mannosidase isoform 1 precursor [Homo sapiens];NP_001166969.1//lysosomal alpha-mannosidase isoform 2 precursor [Homo sapiens]","1//3;3//A2MP1"]
[7023,2147,15.47,15.19,-0.0263513269469523,0.89035388700565,"*",0.828708,"TFAP4","NA","GO:0046983//protein dimerization activity","NA","K09108//transcription factor AP-4","CAG46527.1//TFAP4 [Homo sapiens]","2//1"]
[84440,8277,1.12,1.1,-0.0259952085329446,0.794715795725471,"*",0.705314,"RAB11FIP4","GO:0043231//intracellular membrane-bounded organelle;GO:0005815//microtubule organizing center;GO:0005615//extracellular space;GO:0048471//perinuclear region of cytoplasm;GO:0030496//midbody;GO:0005768//endosome;GO:0055038//recycling endosome membrane;GO:0032154//cleavage furrow;GO:0030139//endocytic vesicle;GO:0005819//spindle","GO:0005509//calcium ion binding;GO:0030306//ADP-ribosylation factor binding;GO:0017137//Rab GTPase binding;GO:0042803//protein homodimerization activity","GO:0006810//transport;GO:0003407//neural retina development;GO:0000910//cytokinesis;GO:0016032//viral process;GO:1903452//positive regulation of G1 to G0 transition","K12485//Rab11 family-interacting protein 3/4","XP_014197570.1//PREDICTED: rab11 family-interacting protein 4 isoform X3 [Pan paniscus];XP_018883627.1//PREDICTED: rab11 family-interacting protein 4 isoform X1 [Gorilla gorilla gorilla];XP_003953123.2//PREDICTED: rab11 family-interacting protein 4 isoform X2 [Pan troglodytes];XP_003812026.1//PREDICTED: rab11 family-interacting protein 4 isoform X1 [Pan paniscus];NP_116321.2//rab11 family-interacting protein 4 isoform 1 [Homo sapiens]","1//3;2//1;5"]
[219931,5026,3.92,3.85,-0.0259952085329444,0.926867285107513,"*",0.874298,"TPCN2","GO:0005765//lysosomal membrane;GO:0010008//endosome membrane;GO:0016021//integral component of membrane;GO:0005764//lysosome;GO:0005886//plasma membrane","GO:0072345//NAADP-sensitive calcium-release channel activity;GO:0005245//voltage-gated calcium channel activity;GO:0042802//identical protein binding;GO:0019901//protein kinase binding","GO:0034220//ion transmembrane transport;GO:0006939//smooth muscle contraction;GO:0019722//calcium-mediated signaling;GO:0033280//response to vitamin D;GO:0086010//membrane depolarization during action potential;GO:0010506//regulation of autophagy;GO:0006874//cellular calcium ion homeostasis;GO:0007040//lysosome organization","K14077//two pore calcium channel protein 2","NP_620714.2//two pore calcium channel protein 2 [Homo sapiens]","3//A2MP1"]
[64708,2501,30.34,29.8,-0.0259087548975095,0.693615936732696,"*",0.576508,"COPS7B","GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0008180//COP9 signalosome","NA","GO:0043687//post-translational protein modification;GO:0000338//protein deneddylation;GO:0000715//nucleotide-excision repair, DNA damage recognition;GO:0006283//transcription-coupled nucleotide-excision repair","K12180//COP9 signalosome complex subunit 7","XP_017198683.1//PREDICTED: COP9 signalosome complex subunit 7b [Oryctolagus cuniculus];XP_012414900.1//PREDICTED: COP9 signalosome complex subunit 7b isoform X4 [Trichechus manatus latirostris];XP_009442824.1//PREDICTED: COP9 signalosome complex subunit 7b isoform X4 [Pan troglodytes];XP_021779815.1//COP9 signalosome complex subunit 7b isoform X1 [Papio anubis];XP_021513817.1//COP9 signalosome complex subunit 7b isoform X1 [Meriones unguiculatus]","1//3;3//A2MP1;2//1"]
[83787,2492,18.66,18.33,-0.0257422003118731,0.760179274717361,"*",0.660862,"ARMC10","GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005789//endoplasmic reticulum membrane","GO:0050692//DBD domain binding;GO:0002039//p53 binding","GO:0040010//positive regulation of growth rate;GO:1902254//negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator;GO:0040008//regulation of growth;GO:0043066//negative regulation of apoptotic process","K11447//histone demethylase [EC:1.14.11.-];K15696//RING finger protein 113B;K17985//activating molecule in BECN1-regulated autophagy protein 1;K10279//F-box and leucine-rich repeat protein 13","NP_001154481.1//armadillo repeat-containing protein 10 isoform b [Homo sapiens];NP_001154484.1//armadillo repeat-containing protein 10 isoform d [Homo sapiens];NP_001154485.1//armadillo repeat-containing protein 10 isoform f [Homo sapiens];NP_001154483.1//armadillo repeat-containing protein 10 isoform e [Homo sapiens];XP_008962092.1//PREDICTED: armadillo repeat-containing protein 10 [Pan paniscus];NP_001154482.1//armadillo repeat-containing protein 10 isoform c [Homo sapiens]","4;2//1"]
[5433,2338,23.86,23.44,-0.02562147327298,0.848134519300651,"*",0.774386,"POLR2D","GO:0005665//DNA-directed RNA polymerase II, core complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0000932//P-body","GO:0003899//DNA-directed 5'-3' RNA polymerase activity;GO:0000166//nucleotide binding;GO:0031369//translation initiation factor binding","GO:0042795//snRNA transcription from RNA polymerase II promoter;GO:0006370//7-methylguanosine mRNA capping;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0035019//somatic stem cell population maintenance;GO:0045948//positive regulation of translational initiation;GO:0031990//mRNA export from nucleus in response to heat stress;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0016070//RNA metabolic process;GO:0000398//mRNA splicing, via spliceosome;GO:0060964//regulation of gene silencing by miRNA;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0050434//positive regulation of viral transcription;GO:0006351//transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter;GO:0034402//recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex;GO:0006367//transcription initiation from RNA polymerase II promoter","K03012//DNA-directed RNA polymerase II subunit RPB4","NP_004796.1//DNA-directed RNA polymerase II subunit RPB4 [Homo sapiens]","3//A2MP1"]
[84978,4951,1.15,1.13,-0.0253110885291875,0.930077546171694,"*",0.878316,"FRMD5","GO:0005856//cytoskeleton;GO:0016021//integral component of membrane;GO:0005912//adherens junction","GO:0005178//integrin binding;GO:0008092//cytoskeletal protein binding;GO:0005200//structural constituent of cytoskeleton;GO:0019901//protein kinase binding","GO:0031032//actomyosin structure organization;GO:0030334//regulation of cell migration;GO:0045785//positive regulation of cell adhesion;GO:2000146//negative regulation of cell motility","K18037//tyrosine-protein phosphatase non-receptor type 4 [EC:3.1.3.48];K06107//erythrocyte membrane protein band 4.1","XP_019500572.1//PREDICTED: FERM domain-containing protein 5 isoform X2 [Hipposideros armiger];NP_001309880.1//FERM domain-containing protein 5 isoform 8 [Homo sapiens];NP_001273420.1//FERM domain-containing protein 5 isoform 4 [Homo sapiens];XP_011920534.1//PREDICTED: FERM domain-containing protein 5 isoform X13 [Cercocebus atys];NP_001309878.1//FERM domain-containing protein 5 isoform 6 [Homo sapiens];NP_116281.2//FERM domain-containing protein 5 isoform 2 [Homo sapiens]","4;1//3"]
[80759,1388,2.31,2.27,-0.0252005541251425,0.890465897639384,"*",0.828868,"KHDC1","GO:0016021//integral component of membrane","GO:0003723//RNA binding","NA","K00658//2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]","NP_001238803.1//KH homology domain-containing protein 1 isoform 1 [Homo sapiens]","1//3;4"]
[8729,6440,17.93,17.62,-0.025161563947961,0.777796853871476,"*",0.680414,"GBF1","GO:0016020//membrane;GO:0005788//endoplasmic reticulum lumen;GO:0031252//cell leading edge;GO:0005777//peroxisome;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005802//trans-Golgi network;GO:0005801//cis-Golgi network;GO:0000139//Golgi membrane;GO:0005795//Golgi stack;GO:0005811//lipid droplet;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0005739//mitochondrion","GO:0080025//phosphatidylinositol-3,5-bisphosphate binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005086//ARF guanyl-nucleotide exchange factor activity","GO:1903409//reactive oxygen species biosynthetic process;GO:0007346//regulation of mitotic cell cycle;GO:0034067//protein localization to Golgi apparatus;GO:0006895//Golgi to endosome transport;GO:0061162//establishment of monopolar cell polarity;GO:2000008//regulation of protein localization to cell surface;GO:0097111//endoplasmic reticulum-Golgi intermediate compartment organization;GO:0048205//COPI coating of Golgi vesicle;GO:0002263//cell activation involved in immune response;GO:0015031//protein transport;GO:0090166//Golgi disassembly;GO:0030593//neutrophil chemotaxis;GO:0042147//retrograde transport, endosome to Golgi;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0007030//Golgi organization;GO:0016032//viral process;GO:1903420//protein localization to endoplasmic reticulum tubular network;GO:0032012//regulation of ARF protein signal transduction;GO:0006892//post-Golgi vesicle-mediated transport;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0098586//cellular response to virus;GO:0070973//protein localization to endoplasmic reticulum exit site","K18443//golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1","NP_004184.1//Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 isoform 1 [Homo sapiens];NP_001186308.1//Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 isoform 3 [Homo sapiens];NP_001186307.1//Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 isoform 2 [Homo sapiens]","1//3;2//1"]
[84842,1803,2.32,2.28,-0.0250909809628302,0.968619857049693,"*",0.929812,"HPDL","NA","GO:0046872//metal ion binding;GO:0003868//4-hydroxyphenylpyruvate dioxygenase activity;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0051213//dioxygenase activity","GO:0009072//aromatic amino acid family metabolic process","K00457//4-hydroxyphenylpyruvate dioxygenase [EC:1.13.11.27]","NP_116145.1//4-hydroxyphenylpyruvate dioxygenase-like protein [Homo sapiens]","2//1"]
[286319,2477,5.81,5.71,-0.0250474180416862,0.937768261380905,"*",0.888514,"TUSC1","NA","NA","NA","K16628//collagen, type VII, alpha;K07604//type I keratin, acidic","NP_001004125.1//tumor suppressor candidate gene 1 protein [Homo sapiens]","2//1"]
[284565,4802,15.13,14.87,-0.0250073401643186,0.819822571249913,"*",0.738682,"NBPF15","GO:0005737//cytoplasm","NA","NA","K22244//regenerating islet-derived protein 4;K05759//profilin;K16549//myomegalin","NP_775909.2//neuroblastoma breakpoint family member 15 [Homo sapiens]","4;2//1"]
[8089,1467,22.14,21.76,-0.0249766655312127,0.656185012809695,"*",0.535538,"YEATS4","GO:0035267//NuA4 histone acetyltransferase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0016363//nuclear matrix","GO:0003677//DNA binding;GO:0008022//protein C-terminus binding;GO:0005200//structural constituent of cytoskeleton;GO:0003700//DNA binding transcription factor activity","GO:0000278//mitotic cell cycle;GO:0006355//regulation of transcription, DNA-templated;GO:0040008//regulation of growth;GO:0043968//histone H2A acetylation;GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0043967//histone H4 acetylation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter","K11341//YEATS domain-containing protein 4","NP_006521.1//YEATS domain-containing protein 4 isoform 1 [Homo sapiens];NP_001287879.1//YEATS domain-containing protein 4 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[9913,4609,18.07,17.76,-0.0249649245144936,0.774838594238211,"*",0.676856,"SUPT7L","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0030914//STAGA complex","GO:0003713//transcription coactivator activity;GO:0004402//histone acetyltransferase activity","GO:0043966//histone H3 acetylation;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0051457//maintenance of protein location in nucleus","K11316//STAGA complex 65 subunit gamma","NP_055675.1//STAGA complex 65 subunit gamma isoform a [Homo sapiens];NP_001269659.1//STAGA complex 65 subunit gamma isoform b [Homo sapiens];NP_001269661.1//STAGA complex 65 subunit gamma isoform c [Homo sapiens]","1//3;2//1"]
[403,3891,8.17,8.03,-0.0249360906283691,0.888228447379059,"*",0.825284,"ARL3","GO:0070062//extracellular exosome;GO:0005929//cilium;GO:0005634//nucleus;GO:0032391//photoreceptor connecting cilium;GO:0005881//cytoplasmic microtubule;GO:0005622//intracellular;GO:0005813//centrosome;GO:0030496//midbody;GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005876//spindle microtubule","GO:0046872//metal ion binding;GO:0019003//GDP binding;GO:0005525//GTP binding;GO:0008017//microtubule binding;GO:0003924//GTPase activity","GO:0000281//mitotic cytokinesis;GO:0060271//cilium assembly;GO:0042073//intraciliary transport;GO:0001822//kidney development;GO:0007264//small GTPase mediated signal transduction;GO:0042461//photoreceptor cell development;GO:0006892//post-Golgi vesicle-mediated transport;GO:0007224//smoothened signaling pathway;GO:0015031//protein transport","K07944//ADP-ribosylation factor-like protein 3","XP_012658993.1//PREDICTED: ADP-ribosylation factor-like protein 3 [Otolemur garnettii]","3//A2MP1"]
[7555,3380,76.47,75.16,-0.0249288073233024,0.678617080736866,"*",0.560388,"CNBP","GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol","GO:0003723//RNA binding;GO:0003676//nucleic acid binding;GO:0001227//transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0003697//single-stranded DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0008270//zinc ion binding;GO:0003700//DNA binding transcription factor activity;GO:0003727//single-stranded RNA binding","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006355//regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006695//cholesterol biosynthetic process;GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0008284//positive regulation of cell proliferation","K09250//cellular nucleic acid-binding protein","ELK15208.1//Cellular nucleic acid-binding protein [Pteropus alecto];NP_001120664.1//cellular nucleic acid-binding protein isoform 1 [Homo sapiens];EDK99231.1//cellular nucleic acid binding protein, isoform CRA_d, partial [Mus musculus]","4;1//3"]
[5871,3027,8.26,8.12,-0.0246620542342692,0.915415643508959,"*",0.860344,"MAP4K2","GO:0016323//basolateral plasma membrane;GO:0005622//intracellular;GO:0005737//cytoplasm;GO:0000139//Golgi membrane","GO:0004674//protein serine/threonine kinase activity;GO:0008349//MAP kinase kinase kinase kinase activity;GO:0005524//ATP binding;GO:0031435//mitogen-activated protein kinase kinase kinase binding","GO:0046330//positive regulation of JNK cascade;GO:0007346//regulation of mitotic cell cycle;GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction;GO:0007254//JNK cascade;GO:0007257//activation of JUN kinase activity;GO:0006903//vesicle targeting;GO:0006955//immune response;GO:0031098//stress-activated protein kinase signaling cascade;GO:0045087//innate immune response;GO:0042981//regulation of apoptotic process","K04414//mitogen-activated protein kinase kinase kinase kinase 2 [EC:2.7.11.1]","NP_004570.2//mitogen-activated protein kinase kinase kinase kinase 2 isoform 1 [Homo sapiens];NP_001294919.1//mitogen-activated protein kinase kinase kinase kinase 2 isoform 2 [Homo sapiens]","1//3;4"]
[26579,2473,87.12,85.65,-0.0245507077455455,0.625840413384291,"*",0.50231,"MYEOV","NA","NA","NA","NA","NP_620123.2//myeloma-overexpressed gene protein isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[3755,2237,4.19,4.12,-0.0243059065161332,0.95184272751149,"*",0.90751,"KCNG1","GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex","GO:0005249//voltage-gated potassium channel activity;GO:0005267//potassium channel activity;GO:0005251//delayed rectifier potassium channel activity","GO:0006813//potassium ion transport;GO:1902259//regulation of delayed rectifier potassium channel activity;GO:0051260//protein homooligomerization;GO:0071805//potassium ion transmembrane transport","K04900//potassium voltage-gated channel subfamily G member 1","NP_002228.2//potassium voltage-gated channel subfamily G member 1 [Homo sapiens]","3//A2MP1"]
[64976,1055,39.58,38.92,-0.0242599022664005,0.867880141886382,"*",0.799532,"MRPL40","GO:0005634//nucleus;GO:0005761//mitochondrial ribosome;GO:0005762//mitochondrial large ribosomal subunit;GO:0005743//mitochondrial inner membrane","GO:0003723//RNA binding","GO:0009653//anatomical structure morphogenesis;GO:0070126//mitochondrial translational termination;GO:0070125//mitochondrial translational elongation","K17421//large subunit ribosomal protein L40","NP_003767.2//39S ribosomal protein L40, mitochondrial isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[27074,3341,0.6,0.59,-0.0242475462466774,0.940997344413666,"*",0.893164,"LAMP3","GO:0005765//lysosomal membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0031982//vesicle;GO:0048471//perinuclear region of cytoplasm;GO:0097233//alveolar lamellar body membrane;GO:0016021//integral component of membrane;GO:0005769//early endosome;GO:0005886//plasma membrane","NA","GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0035455//response to interferon-alpha;GO:1903900//regulation of viral life cycle;GO:0010506//regulation of autophagy;GO:0010628//positive regulation of gene expression;GO:1901799//negative regulation of proteasomal protein catabolic process;GO:0002250//adaptive immune response","K06562//lysosomal-associated membrane protein 3","NP_055213.2//lysosome-associated membrane glycoprotein 3 precursor [Homo sapiens]","3//A2MP1"]
[57001,2068,7.22,7.1,-0.0241798124951267,0.93919022823576,"*",0.890802,"SDHAF3","GO:0005759//mitochondrial matrix;GO:0005758//mitochondrial intermembrane space;GO:0005739//mitochondrion","NA","GO:0006979//response to oxidative stress;GO:0006105//succinate metabolic process;GO:0006111//regulation of gluconeogenesis;GO:0034553//mitochondrial respiratory chain complex II assembly","NA","NP_064571.1//succinate dehydrogenase assembly factor 3, mitochondrial precursor [Homo sapiens]","2//1"]
[3373,2352,1.81,1.78,-0.0241124561168077,0.969339317683881,"*",0.930624,"HYAL1","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0036117//hyaluranon cable;GO:0031410//cytoplasmic vesicle;GO:0043202//lysosomal lumen;GO:0005764//lysosome;GO:0005737//cytoplasm","GO:0008134//transcription factor binding;GO:0004415//hyalurononglucosaminidase activity;GO:0050501//hyaluronan synthase activity","GO:0060272//embryonic skeletal joint morphogenesis;GO:0045785//positive regulation of cell adhesion;GO:0030214//hyaluronan catabolic process;GO:0030307//positive regulation of cell growth;GO:0071356//cellular response to tumor necrosis factor;GO:0071467//cellular response to pH;GO:0051216//cartilage development;GO:0000302//response to reactive oxygen species;GO:0046677//response to antibiotic;GO:0010634//positive regulation of epithelial cell migration;GO:0071347//cellular response to interleukin-1;GO:0030213//hyaluronan biosynthetic process;GO:0030207//chondroitin sulfate catabolic process;GO:0005975//carbohydrate metabolic process;GO:0045766//positive regulation of angiogenesis;GO:0036120//cellular response to platelet-derived growth factor stimulus;GO:0045927//positive regulation of growth;GO:0071493//cellular response to UV-B;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle;GO:0030308//negative regulation of cell growth;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0006954//inflammatory response;GO:1900106//positive regulation of hyaluranon cable assembly;GO:0009615//response to virus;GO:0030212//hyaluronan metabolic process;GO:0050679//positive regulation of epithelial cell proliferation","K01197//hyaluronoglucosaminidase [EC:3.2.1.35]","NP_695014.1//hyaluronidase-1 isoform 2 precursor [Homo sapiens];NP_149349.2//hyaluronidase-1 isoform 1 precursor [Homo sapiens];AAD53277.1//hyaluronoglucosaminidase 1 isoform 2 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[55531,3029,1.21,1.19,-0.0240454739666511,0.963554935528121,"*",0.923442,"ELMOD1","GO:0005654//nucleoplasm;GO:0005829//cytosol","GO:0005096//GTPase activator activity","GO:0031647//regulation of protein stability;GO:1903955//positive regulation of protein targeting to mitochondrion","K12581//CCR4-NOT transcription complex subunit 7/8;K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K11447//histone demethylase [EC:1.14.11.-];K20092//chromodomain-helicase-DNA-binding protein 1-like [EC:3.6.4.12]","BAE21051.1//unnamed protein product, partial [Mus musculus];NP_061182.3//ELMO domain-containing protein 1 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[6236,1467,0.61,0.6,-0.0238467419543678,1.02066196741919,"*",0.996254,"RRAD","GO:0016020//membrane;GO:0005622//intracellular;GO:0005886//plasma membrane","GO:0005525//GTP binding;GO:0005516//calmodulin binding;GO:0003924//GTPase activity","GO:1901842//negative regulation of high voltage-gated calcium channel activity;GO:0007165//signal transduction;GO:0007264//small GTPase mediated signal transduction","K07845//Ras-related associated with diabetes","NP_004156.1//GTP-binding protein RAD [Homo sapiens]","1//3;2//1"]
[5467,3424,9.2,9.05,-0.0237160689738073,1.01180242028986,"*",0.978992,"PPARD","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000790//nuclear chromatin","GO:0003707//steroid hormone receptor activity;GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity;GO:0004879//nuclear receptor activity;GO:0001227//transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0008289//lipid binding;GO:0003713//transcription coactivator activity;GO:0051059//NF-kappaB binding;GO:0008144//drug binding;GO:0070539//linoleic acid binding;GO:0008270//zinc ion binding;GO:0043565//sequence-specific DNA binding;GO:0005504//fatty acid binding;GO:0008134//transcription factor binding","GO:0045684//positive regulation of epidermis development;GO:0043616//keratinocyte proliferation;GO:0097190//apoptotic signaling pathway;GO:0071222//cellular response to lipopolysaccharide;GO:0001890//placenta development;GO:0050728//negative regulation of inflammatory response;GO:0007566//embryo implantation;GO:0008366//axon ensheathment;GO:0008654//phospholipid biosynthetic process;GO:0009749//response to glucose;GO:0051546//keratinocyte migration;GO:0006776//vitamin A metabolic process;GO:0033189//response to vitamin A;GO:0046697//decidualization;GO:0030154//cell differentiation;GO:0015908//fatty acid transport;GO:0007507//heart development;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0009299//mRNA transcription;GO:0043066//negative regulation of apoptotic process;GO:2000288//positive regulation of myoblast proliferation;GO:0010628//positive regulation of gene expression;GO:0006915//apoptotic process;GO:0045662//negative regulation of myoblast differentiation;GO:1902894//negative regulation of pri-miRNA transcription from RNA polymerase II promoter;GO:0014842//regulation of skeletal muscle satellite cell proliferation;GO:0071456//cellular response to hypoxia;GO:0032024//positive regulation of insulin secretion;GO:0097755//positive regulation of blood vessel diameter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006635//fatty acid beta-oxidation;GO:0043415//positive regulation of skeletal muscle tissue regeneration;GO:0030308//negative regulation of cell growth;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0045598//regulation of fat cell differentiation;GO:0032966//negative regulation of collagen biosynthetic process;GO:0014823//response to activity;GO:0042060//wound healing;GO:0006351//transcription, DNA-templated;GO:0006029//proteoglycan metabolic process;GO:0031589//cell-substrate adhesion;GO:0060612//adipose tissue development;GO:0014912//negative regulation of smooth muscle cell migration;GO:0050680//negative regulation of epithelial cell proliferation","K04504//peroxisome proliferator-activated receptor delta","NP_006229.1//peroxisome proliferator-activated receptor delta isoform 1 [Homo sapiens];NP_803184.1//peroxisome proliferator-activated receptor delta isoform 2 [Homo sapiens];NP_001165290.1//peroxisome proliferator-activated receptor delta isoform 3 [Homo sapiens];NP_001165291.1//peroxisome proliferator-activated receptor delta isoform 4 [Homo sapiens]","4;1//3;2//1"]
[5536,2213,73.42,72.23,-0.0235749440583918,0.632805417325456,"*",0.47605,"PPP5C","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:1990635//proximal dendrite;GO:0043234//protein complex;GO:0005829//cytosol;GO:0071944//cell periphery;GO:0005886//plasma membrane;GO:0043204//perikaryon","GO:0003723//RNA binding;GO:0005524//ATP binding;GO:0031072//heat shock protein binding;GO:0042802//identical protein binding;GO:0004722//protein serine/threonine phosphatase activity;GO:0008017//microtubule binding;GO:0043531//ADP binding;GO:0008289//lipid binding;GO:0051879//Hsp90 protein binding;GO:0046872//metal ion binding;GO:0001965//G-protein alpha-subunit binding;GO:0004721//phosphoprotein phosphatase activity;GO:0004871//signal transducer activity","GO:0051291//protein heterooligomerization;GO:1901215//negative regulation of neuron death;GO:0000278//mitotic cell cycle;GO:0000165//MAPK cascade;GO:0006281//DNA repair;GO:0016576//histone dephosphorylation;GO:0043278//response to morphine;GO:0006351//transcription, DNA-templated;GO:2000324//positive regulation of glucocorticoid receptor signaling pathway;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0010288//response to lead ion;GO:0001933//negative regulation of protein phosphorylation;GO:0006470//protein dephosphorylation;GO:0071276//cellular response to cadmium ion;GO:0070301//cellular response to hydrogen peroxide","K04460//serine/threonine-protein phosphatase 5 [EC:3.1.3.16]","NP_006238.1//serine/threonine-protein phosphatase 5 isoform 1 [Homo sapiens];NP_001191213.1//serine/threonine-protein phosphatase 5 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[84968,2278,4.32,4.25,-0.0235684711384045,0.953725742392445,"*",0.91038,"PNMA6A","NA","NA","NA","K06236//collagen, type I, alpha;K19720//collagen, type III, alpha","NP_116271.3//paraneoplastic antigen-like protein 6A [Homo sapiens]",5]
[665,3505,15.43,15.18,-0.0235662711552686,0.862199806486781,"*",0.79214,"BNIP3L","GO:0005740//mitochondrial envelope;GO:0005783//endoplasmic reticulum;GO:0005635//nuclear envelope;GO:0016607//nuclear speck;GO:0005741//mitochondrial outer membrane;GO:0031224//intrinsic component of membrane;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005739//mitochondrion","GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0005521//lamin binding","GO:0071456//cellular response to hypoxia;GO:0043069//negative regulation of programmed cell death;GO:0035694//mitochondrial protein catabolic process;GO:0051607//defense response to virus;GO:1903146//regulation of autophagy of mitochondrion;GO:0043066//negative regulation of apoptotic process;GO:0016032//viral process;GO:0043065//positive regulation of apoptotic process;GO:0016239//positive regulation of macroautophagy;GO:1903214//regulation of protein targeting to mitochondrion;GO:0097345//mitochondrial outer membrane permeabilization;GO:0010917//negative regulation of mitochondrial membrane potential;GO:0060548//negative regulation of cell death;GO:0042981//regulation of apoptotic process;GO:0035794//positive regulation of mitochondrial membrane permeability","K15465//BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like","ERE87539.1//serine/threonine-protein phosphatase 2A regulatory subunit B alpha isoform [Cricetulus griseus];XP_003272940.2//PREDICTED: BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like isoform X1 [Nomascus leucogenys]","1//3;2//1"]
[80775,1484,23.06,22.69,-0.0233359039794343,0.805650390555829,"*",0.717742,"TMEM177","GO:0016021//integral component of membrane","NA","NA","NA","XP_008970744.2//PREDICTED: transmembrane protein 177 isoform X1 [Pan paniscus]","1//3;2//1"]
[162968,3521,2.51,2.47,-0.0231763223660943,0.90972837007348,"*",0.85255,"ZNF497","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_007505752.1//PREDICTED: zinc finger protein 497 [Monodelphis domestica]","1//3;2//1"]
[4598,2068,19.48,19.17,-0.0231433404141915,0.944499169289524,"*",0.897966,"MVK","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0004496//mevalonate kinase activity","GO:0008299//isoprenoid biosynthetic process;GO:0019287//isopentenyl diphosphate biosynthetic process, mevalonate pathway;GO:0006695//cholesterol biosynthetic process;GO:0050728//negative regulation of inflammatory response;GO:0045540//regulation of cholesterol biosynthetic process","K00869//mevalonate kinase [EC:2.7.1.36]","NP_001288111.1//mevalonate kinase isoform b [Homo sapiens];BAD92959.1//mevalonate kinase variant, partial [Homo sapiens]","1//3;3//A2MP1;2//1"]
[84321,1617,63.58,62.57,-0.0231019124386378,0.812180366764582,"*",0.726966,"THOC3","GO:0000784//nuclear chromosome, telomeric region;GO:0005654//nucleoplasm;GO:0000445//THO complex part of transcription export complex;GO:0016607//nuclear speck;GO:0000346//transcription export complex","GO:0003723//RNA binding","GO:0006406//mRNA export from nucleus;GO:0046784//viral mRNA export from host cell nucleus;GO:0006369//termination of RNA polymerase II transcription;GO:0008380//RNA splicing;GO:0031124//mRNA 3'-end processing;GO:0006405//RNA export from nucleus","K12880//THO complex subunit 3","XP_019493024.1//PREDICTED: THO complex subunit 3 [Hipposideros armiger]","3//A2MP1"]
[54802,2146,5.68,5.59,-0.0230426466614919,0.857977458891013,"*",0.786542,"TRIT1","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0005524//ATP binding;GO:0008270//zinc ion binding;GO:0016740//transferase activity;GO:0052381//tRNA dimethylallyltransferase activity;GO:0003676//nucleic acid binding","GO:0006400//tRNA modification;GO:0070900//mitochondrial tRNA modification;GO:0008033//tRNA processing","K00791//tRNA dimethylallyltransferase [EC:2.5.1.75]","NP_060116.2//tRNA dimethylallyltransferase, mitochondrial isoform 1 precursor [Homo sapiens];NP_001299620.1//tRNA dimethylallyltransferase, mitochondrial isoform 2 [Homo sapiens];NP_001299621.1//tRNA dimethylallyltransferase, mitochondrial isoform 3 [Homo sapiens]","1//3;5"]
[10287,1571,20.28,19.96,-0.0229459316660799,0.92998459162026,"*",0.87817,"RGS19","GO:0016020//membrane;GO:0045121//membrane raft;GO:0005903//brush border;GO:0005794//Golgi apparatus;GO:0031410//cytoplasmic vesicle;GO:0030136//clathrin-coated vesicle","GO:0001965//G-protein alpha-subunit binding;GO:0005096//GTPase activator activity","GO:0007186//G-protein coupled receptor signaling pathway;GO:0007264//small GTPase mediated signal transduction;GO:0009968//negative regulation of signal transduction;GO:0006914//autophagy","K16449//regulator of G-protein signaling","NP_005864.1//regulator of G-protein signaling 19 [Homo sapiens];XP_005604926.1//PREDICTED: regulator of G-protein signaling 19 isoform X1 [Equus caballus]","1//3;2//1"]
[51071,1821,19.71,19.4,-0.022871123968996,0.896722175278486,"*",0.836544,"DERA","GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005829//cytosol;GO:1904813//ficolin-1-rich granule lumen;GO:0005576//extracellular region;GO:0005737//cytoplasm","GO:0004139//deoxyribose-phosphate aldolase activity","GO:0006098//pentose-phosphate shunt;GO:0043312//neutrophil degranulation;GO:0046386//deoxyribose phosphate catabolic process;GO:0009264//deoxyribonucleotide catabolic process;GO:0046121//deoxyribonucleoside catabolic process;GO:0016052//carbohydrate catabolic process","K01619//deoxyribose-phosphate aldolase [EC:4.1.2.4]","AAH56234.1//DERA protein, partial [Homo sapiens]","1//3;3//A2MP1"]
[54554,4183,2.55,2.51,-0.022809882908086,0.956984395915161,"*",0.915168,"WDR5B","GO:0036064//ciliary basal body","NA","GO:0060271//cilium assembly","K14963//COMPASS component SWD3","XP_021548341.1//WD repeat-containing protein 5B [Neomonachus schauinslandi]","3//A2MP1"]
[55041,4249,31.38,30.89,-0.0227054813404598,0.583504690527035,"*",0.427638,"PLEKHB2","GO:0055038//recycling endosome membrane;GO:0016021//integral component of membrane","GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding","GO:0045595//regulation of cell differentiation","K12581//CCR4-NOT transcription complex subunit 7/8;K07560//D-tyrosyl-tRNA(Tyr) deacylase [EC:3.1.-.-];K16506//protocadherin Fat 1/2/3;K08857//NIMA (never in mitosis gene a)-related kinase 1/4/5 [EC:2.7.11.1];K00968//choline-phosphate cytidylyltransferase [EC:2.7.7.15];K04487//cysteine desulfurase [EC:2.8.1.7]","NP_001094093.1//pleckstrin homology domain-containing family B member 2 isoform 3 [Homo sapiens];NP_060428.2//pleckstrin homology domain-containing family B member 2 isoform 2 [Homo sapiens];XP_016804803.1//PREDICTED: pleckstrin homology domain-containing family B member 2 isoform X3 [Pan troglodytes];XP_016804807.1//PREDICTED: pleckstrin homology domain-containing family B member 2 isoform X7 [Pan troglodytes];NP_001253997.1//pleckstrin homology domain-containing family B member 2 isoform 10 [Homo sapiens];NP_001253995.1//pleckstrin homology domain-containing family B member 2 isoform 8 [Homo sapiens];XP_016804806.1//PREDICTED: pleckstrin homology domain-containing family B member 2 isoform X6 [Pan troglodytes];NP_001296379.1//pleckstrin homology domain-containing family B member 2 isoform 12 [Homo sapiens];NP_001253996.1//pleckstrin homology domain-containing family B member 2 isoform 9 [Homo sapiens];XP_016804808.1//PREDICTED: pleckstrin homology domain-containing family B member 2 isoform X8 [Pan troglodytes];XP_016804805.1//PREDICTED: pleckstrin homology domain-containing family B member 2 isoform X5 [Pan troglodytes];XP_016804804.1//PREDICTED: pleckstrin homology domain-containing family B member 2 isoform X4 [Pan troglodytes]","1//3;2//1"]
[10197,3457,146.2,143.93,-0.0225759802246578,0.617093238087262,"*",0.461294,"PSME3","GO:0016020//membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000502//proteasome complex;GO:0005829//cytosol;GO:0008537//proteasome activator complex;GO:0005737//cytoplasm","GO:0008233//peptidase activity;GO:0061133//endopeptidase activator activity;GO:0002039//p53 binding;GO:0042802//identical protein binding;GO:0097371//MDM2/MDM4 family protein binding","GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:0043687//post-translational protein modification;GO:0038061//NIK/NF-kappaB signaling;GO:0010950//positive regulation of endopeptidase activity;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0006521//regulation of cellular amino acid metabolic process;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0016579//protein deubiquitination;GO:0043488//regulation of mRNA stability;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0000209//protein polyubiquitination;GO:0055085//transmembrane transport;GO:0000165//MAPK cascade;GO:0050852//T cell receptor signaling pathway;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0061136//regulation of proteasomal protein catabolic process;GO:0006915//apoptotic process;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:1902036//regulation of hematopoietic stem cell differentiation;GO:0007049//cell cycle","K06698//proteasome activator subunit 3 (PA28 gamma)","NP_035322.1//proteasome activator complex subunit 3 [Mus musculus];XP_011854159.1//PREDICTED: proteasome activator complex subunit 3 isoform X1 [Mandrillus leucophaeus];NP_789839.1//proteasome activator complex subunit 3 isoform 2 [Homo sapiens];XP_021579933.1//proteasome activator complex subunit 3 isoform X2 [Ictidomys tridecemlineatus]","1//3;3//A2MP1;2//1"]
[200030,5397,2.6,2.56,-0.0223678130284546,0.710440073731343,"*",0.595962,"NBPF11","GO:0005737//cytoplasm","NA","NA","K22244//regenerating islet-derived protein 4;K16549//myomegalin","NP_001265070.1//neuroblastoma breakpoint family member 12 [Homo sapiens]","4;5"]
[2281,868,4.6,4.53,-0.02212281089814,0.7937222918461,"*",0.703836,"FKBP1B","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0030018//Z disc;GO:0005829//cytosol;GO:0034704//calcium channel complex;GO:0033017//sarcoplasmic reticulum membrane;GO:0005737//cytoplasm;GO:0016529//sarcoplasmic reticulum","GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0044325//ion channel binding;GO:0030551//cyclic nucleotide binding;GO:0019855//calcium channel inhibitor activity;GO:0005528//FK506 binding;GO:0005102//receptor binding","GO:0034220//ion transmembrane transport;GO:0032515//negative regulation of phosphoprotein phosphatase activity;GO:0030073//insulin secretion;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0061077//chaperone-mediated protein folding;GO:0033197//response to vitamin E;GO:0009749//response to glucose;GO:0060314//regulation of ryanodine-sensitive calcium-release channel activity;GO:0061179//negative regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0006458//'de novo' protein folding;GO:0019227//neuronal action potential propagation;GO:0051775//response to redox state;GO:0051209//release of sequestered calcium ion into cytosol;GO:0060315//negative regulation of ryanodine-sensitive calcium-release channel activity;GO:0014808//release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0051284//positive regulation of sequestering of calcium ion;GO:0035584//calcium-mediated signaling using intracellular calcium source;GO:0022417//protein maturation by protein folding;GO:0010459//negative regulation of heart rate;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0010033//response to organic substance;GO:0086064//cell communication by electrical coupling involved in cardiac conduction;GO:0000413//protein peptidyl-prolyl isomerization;GO:0010881//regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion;GO:1903779//regulation of cardiac conduction;GO:0006939//smooth muscle contraction;GO:0048680//positive regulation of axon regeneration;GO:0042542//response to hydrogen peroxide;GO:0002027//regulation of heart rate;GO:0051280//negative regulation of release of sequestered calcium ion into cytosol;GO:0042098//T cell proliferation;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0042026//protein refolding","K09568//FK506-binding protein 1 [EC:5.2.1.8]","XP_004582689.1//PREDICTED: peptidyl-prolyl cis-trans isomerase FKBP1B isoform X1 [Ochotona princeps];XP_011806202.1//PREDICTED: peptidyl-prolyl cis-trans isomerase FKBP1B isoform X2 [Colobus angolensis palliatus];NP_004107.1//peptidyl-prolyl cis-trans isomerase FKBP1B isoform a [Homo sapiens]","4;1//3;3//A2MP1"]
[375061,1516,14.47,14.25,-0.0221030025922583,0.932116811816917,"*",0.880942,"FAM89A","NA","NA","NA","K19941//synapsin;K16608//tubulin monoglycylase TTLL3/8 [EC:6.3.2.-]","NP_940954.1//protein FAM89A [Homo sapiens]","2//1"]
[84623,3758,3.29,3.24,-0.0220937708506167,0.963461354063235,"*",0.923292,"KIRREL3","GO:0043198//dendritic shaft;GO:0030425//dendrite;GO:0030424//axon;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane","NA","GO:0021740//principal sensory nucleus of trigeminal nerve development;GO:0021766//hippocampus development;GO:0007416//synapse assembly;GO:0072102//glomerulus morphogenesis;GO:0002121//inter-male aggressive behavior;GO:0001764//neuron migration;GO:0048812//neuron projection morphogenesis;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0030097//hemopoiesis","K16680//echinoid;K18273//alpha-tectorin","NP_001155179.1//kin of IRRE-like protein 3 isoform 2 precursor [Homo sapiens];NP_115920.1//kin of IRRE-like protein 3 isoform 1 precursor [Homo sapiens];NP_001288026.1//kin of IRRE-like protein 3 isoform 3 precursor [Homo sapiens]","1//3;3//A2MP1"]
[2588,2304,28.37,27.94,-0.0220341298648957,0.926169657085961,"*",0.873466,"GALNS","GO:0070062//extracellular exosome;GO:0035578//azurophil granule lumen;GO:0043202//lysosomal lumen;GO:0005576//extracellular region","GO:0046872//metal ion binding;GO:0008484//sulfuric ester hydrolase activity;GO:0043890//N-acetylgalactosamine-6-sulfatase activity;GO:0003943//N-acetylgalactosamine-4-sulfatase activity","GO:0008152//metabolic process;GO:0042340//keratan sulfate catabolic process;GO:0043312//neutrophil degranulation","K01132//N-acetylgalactosamine-6-sulfatase [EC:3.1.6.4]","NP_001310473.1//N-acetylgalactosamine-6-sulfatase isoform 2 [Homo sapiens];XP_007992549.1//PREDICTED: LOW QUALITY PROTEIN: N-acetylgalactosamine-6-sulfatase [Chlorocebus sabaeus]","1//3;4"]
[7385,2226,77.24,76.07,-0.0220205592393431,0.767650974660828,"*",0.669472,"UQCRC2","GO:0070062//extracellular exosome;GO:0005654//nucleoplasm;GO:0043209//myelin sheath;GO:0005750//mitochondrial respiratory chain complex III;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0005751//mitochondrial respiratory chain complex IV","GO:0046872//metal ion binding;GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding;GO:0032403//protein complex binding","GO:0006627//protein processing involved in protein targeting to mitochondrion;GO:0006119//oxidative phosphorylation;GO:0009060//aerobic respiration;GO:0006122//mitochondrial electron transport, ubiquinol to cytochrome c","K00415//ubiquinol-cytochrome c reductase core subunit 2","NP_003357.2//cytochrome b-c1 complex subunit 2, mitochondrial precursor [Homo sapiens]","3//A2MP1"]
[84759,939,23.14,22.79,-0.0219879398421928,0.93021023223754,"*",0.878616,"PCGF1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031519//PcG protein complex","GO:0046872//metal ion binding;GO:0008022//protein C-terminus binding","GO:0035518//histone H2A monoubiquitination;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0036353//histone H2A-K119 monoubiquitination","K11487//polycomb group RING finger protein 1","NP_116062.2//polycomb group RING finger protein 1 [Homo sapiens]","2//1"]
[50515,5759,7.28,7.17,-0.0219653314967916,0.891461128639634,"*",0.829906,"CHST11","GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0001537//N-acetylgalactosamine 4-O-sulfotransferase activity;GO:0047756//chondroitin 4-sulfotransferase activity;GO:0008146//sulfotransferase activity;GO:0050659//N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity","GO:0007585//respiratory gaseous exchange;GO:0016051//carbohydrate biosynthetic process;GO:0042127//regulation of cell proliferation;GO:0048703//embryonic viscerocranium morphogenesis;GO:0030206//chondroitin sulfate biosynthetic process;GO:0002063//chondrocyte development;GO:0043066//negative regulation of apoptotic process;GO:0036342//post-anal tail morphogenesis;GO:0042733//embryonic digit morphogenesis;GO:0009791//post-embryonic development;GO:0033037//polysaccharide localization;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0048589//developmental growth","K01017//chondroitin 4-sulfotransferase 11 [EC:2.8.2.5]","NP_060883.1//carbohydrate sulfotransferase 11 isoform 1 [Homo sapiens];NP_001167453.1//carbohydrate sulfotransferase 11 isoform 2 [Homo sapiens]","1//3;5"]
[1018,1584,6.63,6.53,-0.0219258785661569,0.955732329578203,"*",0.913492,"CDK3","GO:0005634//nucleus;GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0005737//cytoplasm","GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0030332//cyclin binding","GO:0010468//regulation of gene expression;GO:0007165//signal transduction;GO:0006468//protein phosphorylation;GO:0010389//regulation of G2/M transition of mitotic cell cycle;GO:0008283//cell proliferation;GO:0045023//G0 to G1 transition;GO:0010033//response to organic substance;GO:0051301//cell division;GO:0007275//multicellular organism development;GO:0000082//G1/S transition of mitotic cell cycle;GO:0006974//cellular response to DNA damage stimulus;GO:0008284//positive regulation of cell proliferation","K02088//cyclin-dependent kinase 3 [EC:2.7.11.22]","XP_008964060.1//PREDICTED: cyclin-dependent kinase 3 isoform X1 [Pan paniscus]","2//1"]
[8220,5405,4.01,3.95,-0.021749583390455,0.932830821721854,"*",0.881792,"ESS2","GO:0005634//nucleus;GO:0071013//catalytic step 2 spliceosome","NA","GO:0007399//nervous system development;GO:0000398//mRNA splicing, via spliceosome","K13118//protein DGCR14","XP_017712197.1//PREDICTED: protein DGCR14 [Rhinopithecus bieti]","2//1"]
[2806,2441,130.84,128.91,-0.0214394815876836,0.590906050923955,"*",0.434394,"GOT2","GO:0005759//mitochondrial matrix;GO:0070062//extracellular exosome;GO:0009986//cell surface;GO:0043234//protein complex;GO:0043209//myelin sheath;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0043204//perikaryon","GO:0047578//4-hydroxyglutamate transaminase activity;GO:0003723//RNA binding;GO:0016597//amino acid binding;GO:0004069//L-aspartate:2-oxoglutarate aminotransferase activity;GO:0016212//kynurenine-oxoglutarate transaminase activity;GO:0042803//protein homodimerization activity;GO:0005543//phospholipid binding;GO:0080130//L-phenylalanine:2-oxoglutarate aminotransferase activity;GO:0030170//pyridoxal phosphate binding;GO:0019899//enzyme binding","GO:0019550//glutamate catabolic process to aspartate;GO:0008652//cellular amino acid biosynthetic process;GO:0015908//fatty acid transport;GO:0006531//aspartate metabolic process;GO:0006532//aspartate biosynthetic process;GO:0006094//gluconeogenesis;GO:0019470//4-hydroxyproline catabolic process;GO:0019551//glutamate catabolic process to 2-oxoglutarate;GO:0045471//response to ethanol;GO:0006533//aspartate catabolic process;GO:0006536//glutamate metabolic process;GO:0006107//oxaloacetate metabolic process;GO:0006103//2-oxoglutarate metabolic process;GO:0046487//glyoxylate metabolic process","K14455//aspartate aminotransferase, mitochondrial [EC:2.6.1.1]","NP_001273149.1//aspartate aminotransferase, mitochondrial isoform 2 precursor [Homo sapiens];NP_002071.2//aspartate aminotransferase, mitochondrial isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[5581,5537,2.04,2.01,-0.0213736507925672,0.960110032842656,"*",0.918698,"PRKCE","GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0071944//cell periphery;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0005739//mitochondrion;GO:0005886//plasma membrane","GO:0030546//receptor activator activity;GO:0005524//ATP binding;GO:0004697//protein kinase C activity;GO:0003785//actin monomer binding;GO:0035276//ethanol binding;GO:0071889//14-3-3 protein binding;GO:0046872//metal ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0004699//calcium-independent protein kinase C activity;GO:0004871//signal transducer activity;GO:0008047//enzyme activator activity;GO:0019899//enzyme binding","GO:0010763//positive regulation of fibroblast migration;GO:2001031//positive regulation of cellular glucuronidation;GO:0050730//regulation of peptidyl-tyrosine phosphorylation;GO:0035669//TRAM-dependent toll-like receptor 4 signaling pathway;GO:1903078//positive regulation of protein localization to plasma membrane;GO:2000650//negative regulation of sodium ion transmembrane transporter activity;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0032467//positive regulation of cytokinesis;GO:0071361//cellular response to ethanol;GO:0007165//signal transduction;GO:0006468//protein phosphorylation;GO:0035641//locomotory exploration behavior;GO:0050996//positive regulation of lipid catabolic process;GO:0006915//apoptotic process;GO:0090303//positive regulation of wound healing;GO:0007155//cell adhesion;GO:0032230//positive regulation of synaptic transmission, GABAergic;GO:0018105//peptidyl-serine phosphorylation;GO:0071380//cellular response to prostaglandin E stimulus;GO:0007202//activation of phospholipase C activity;GO:0051209//release of sequestered calcium ion into cytosol;GO:0071456//cellular response to hypoxia;GO:0031397//negative regulation of protein ubiquitination;GO:0032024//positive regulation of insulin secretion;GO:0070257//positive regulation of mucus secretion;GO:0043278//response to morphine;GO:0051279//regulation of release of sequestered calcium ion into cytosol;GO:0035556//intracellular signal transduction;GO:0030168//platelet activation;GO:0010634//positive regulation of epithelial cell migration;GO:0061178//regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0002281//macrophage activation involved in immune response;GO:0030838//positive regulation of actin filament polymerization;GO:0010811//positive regulation of cell-substrate adhesion;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0051301//cell division;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0043410//positive regulation of MAPK cascade;GO:0007049//cell cycle","K18050//novel protein kinase C epsilon type [EC:2.7.11.13]","NP_005391.1//protein kinase C epsilon type [Homo sapiens]","2//1"]
[55884,2819,37.12,36.58,-0.0211416353788556,0.543724799300699,"*",0.389396,"WSB2","GO:0005829//cytosol;GO:0005622//intracellular","NA","GO:0043687//post-translational protein modification;GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction","K10342//WD repeat and SOCS box-containing protein 2","XP_012805499.1//PREDICTED: WD repeat and SOCS box-containing protein 2 isoform X2 [Jaculus jaculus];NP_001265486.1//WD repeat and SOCS box-containing protein 2 isoform 1 [Homo sapiens];XP_021531172.1//WD repeat and SOCS box-containing protein 2 [Aotus nancymaae]","1//3;4"]
[8559,1711,6.88,6.78,-0.0211232915657539,0.960892877640442,"*",0.919808,"PRPF18","GO:0005634//nucleus;GO:0071021//U2-type post-spliceosomal complex;GO:0005681//spliceosomal complex;GO:0005682//U5 snRNP;GO:0016607//nuclear speck;GO:0046540//U4/U6 x U5 tri-snRNP complex","NA","GO:0071048//nuclear retention of unspliced pre-mRNA at the site of transcription;GO:0006397//mRNA processing;GO:0000350//generation of catalytic spliceosome for second transesterification step;GO:0008380//RNA splicing","K12817//pre-mRNA-splicing factor 18","XP_002717659.3//PREDICTED: pre-mRNA-splicing factor 18 [Oryctolagus cuniculus]","3//A2MP1"]
[84320,1617,27.52,27.12,-0.0211232915657539,0.89503772035208,"*",0.833908,"ACBD6","GO:0005829//cytosol","GO:0008289//lipid binding;GO:0000062//fatty-acyl-CoA binding","GO:0006637//acyl-CoA metabolic process","K10799//tankyrase [EC:2.4.2.30]","NP_115736.1//acyl-CoA-binding domain-containing protein 6 [Homo sapiens]","3//A2MP1"]
[152137,8604,3.46,3.41,-0.021000298612552,0.926854587641866,"*",0.874228,"CCDC50","GO:0005829//cytosol","GO:0031625//ubiquitin protein ligase binding","GO:0007605//sensory perception of sound","K12581//CCR4-NOT transcription complex subunit 7/8;K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K17985//activating molecule in BECN1-regulated autophagy protein 1;K01064//wingless-type MMTV integration site family, member 9","XP_011379793.1//PREDICTED: coiled-coil domain-containing protein 50 [Pteropus vampyrus];NP_848018.1//coiled-coil domain-containing protein 50 long isoform [Homo sapiens]","3//A2MP1;2//1"]
[57109,2349,19.45,19.17,-0.0209198182054035,0.536755007637609,"*",0.382758,"REXO4","GO:0005634//nucleus;GO:0005730//nucleolus;GO:0016607//nuclear speck","GO:0003723//RNA binding;GO:0004527//exonuclease activity;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated","K18327//RNA exonuclease 4 [EC:3.1.-.-]","NP_001266278.1//RNA exonuclease 4 isoform 2 [Homo sapiens];NP_065118.2//RNA exonuclease 4 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[9861,1395,37.09,36.56,-0.02076419744494,0.45156685410844,"*",0.303438,"PSMD6","GO:0034774//secretory granule lumen;GO:0070062//extracellular exosome;GO:0005654//nucleoplasm;GO:0000502//proteasome complex;GO:0022624//proteasome accessory complex;GO:0005838//proteasome regulatory particle;GO:0005829//cytosol;GO:0005576//extracellular region;GO:1904813//ficolin-1-rich granule lumen","GO:0030234//enzyme regulator activity;GO:0016887//ATPase activity","GO:0043687//post-translational protein modification;GO:0038061//NIK/NF-kappaB signaling;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0006521//regulation of cellular amino acid metabolic process;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0016579//protein deubiquitination;GO:0043312//neutrophil degranulation;GO:0043488//regulation of mRNA stability;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0000209//protein polyubiquitination;GO:0055085//transmembrane transport;GO:0000165//MAPK cascade;GO:0050852//T cell receptor signaling pathway;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0006508//proteolysis;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:1902036//regulation of hematopoietic stem cell differentiation","K03037//26S proteasome regulatory subunit N7","NP_001258709.1//26S proteasome non-ATPase regulatory subunit 6 isoform 3 [Homo sapiens];XP_017382846.1//PREDICTED: 26S proteasome non-ATPase regulatory subunit 6 [Cebus capucinus imitator];NP_001258710.1//26S proteasome non-ATPase regulatory subunit 6 isoform 4 [Homo sapiens];NP_001258708.1//26S proteasome non-ATPase regulatory subunit 6 isoform 1 [Homo sapiens]","1//3;2//1"]
[1949,3236,1.4,1.38,-0.0207585601667975,0.971878312263782,"*",0.93367,"EFNB3","GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0046875//ephrin receptor binding;GO:0016301//kinase activity;GO:0001618//virus receptor activity;GO:0005005//transmembrane-ephrin receptor activity","GO:0007399//nervous system development;GO:0016198//axon choice point recognition;GO:0048013//ephrin receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0031295//T cell costimulation;GO:0007628//adult walking behavior;GO:0050771//negative regulation of axonogenesis;GO:0007411//axon guidance","K05463//ephrin-B","NP_001397.1//ephrin-B3 precursor [Homo sapiens]","3//A2MP1"]
[57226,5371,5.63,5.55,-0.0206471508427613,0.929159453544665,"*",0.8771,"LYRM2","GO:0005739//mitochondrion","NA","NA","K12824//transcription elongation regulator 1","XP_004310756.2//PREDICTED: LYR motif-containing protein 2 [Tursiops truncatus]",4]
[53947,2156,7.84,7.73,-0.0203852401903607,0.945131135789474,"*",0.899336,"A4GALT","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0030173//integral component of Golgi membrane;GO:0016021//integral component of membrane","GO:0016757//transferase activity, transferring glycosyl groups;GO:0015643//toxic substance binding;GO:0050512//lactosylceramide 4-alpha-galactosyltransferase activity;GO:0008378//galactosyltransferase activity","GO:0006486//protein glycosylation;GO:0006688//glycosphingolipid biosynthetic process;GO:0001576//globoside biosynthetic process;GO:0007009//plasma membrane organization","K01988//lactosylceramide 4-alpha-galactosyltransferase [EC:2.4.1.228]","NP_059132.1//lactosylceramide 4-alpha-galactosyltransferase [Homo sapiens]","6;2//1"]
[5018,1737,151.91,149.79,-0.0202755308440995,0.734171366336634,"*",0.631312,"OXA1L","GO:0043234//protein complex;GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0031966//mitochondrial membrane;GO:0005746//mitochondrial respiratory chain;GO:0032592//integral component of mitochondrial membrane","GO:0097177//mitochondrial ribosome binding;GO:0042803//protein homodimerization activity","GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0032780//negative regulation of ATPase activity;GO:0097031//mitochondrial respiratory chain complex I biogenesis;GO:0051262//protein tetramerization;GO:0051354//negative regulation of oxidoreductase activity;GO:0055114//oxidation-reduction process;GO:0009060//aerobic respiration;GO:0033615//mitochondrial proton-transporting ATP synthase complex assembly;GO:0051205//protein insertion into membrane;GO:0006461//protein complex assembly","K03217//YidC/Oxa1 family membrane protein insertase","NP_005006.3//mitochondrial inner membrane protein OXA1L [Homo sapiens]","3//A2MP1"]
[5954,2529,78.48,77.39,-0.0201778819376304,0.775383315947843,"*",0.677526,"RCN1","GO:0005783//endoplasmic reticulum","GO:0005509//calcium ion binding","GO:0043010//camera-type eye development;GO:0001701//in utero embryonic development","K19934//calcium-binding protein;K12804//proline-serine-threonine phosphatase interacting protein 1;K17286//erythrocyte band 7 integral membrane protein","XP_003353965.2//reticulocalbin-1 [Sus scrofa]","2//1"]
[8314,3717,18.83,18.57,-0.0200591846788074,0.873211372235039,"*",0.805646,"BAP1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0035517//PR-DUB complex;GO:0005737//cytoplasm","GO:0004843//thiol-dependent ubiquitin-specific protease activity;GO:0008233//peptidase activity;GO:0003682//chromatin binding;GO:0036459//thiol-dependent ubiquitinyl hydrolase activity","GO:0001558//regulation of cell growth;GO:0071108//protein K48-linked deubiquitination;GO:1900015//regulation of cytokine production involved in inflammatory response;GO:1903955//positive regulation of protein targeting to mitochondrion;GO:0035522//monoubiquitinated histone H2A deubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006464//cellular protein modification process;GO:0010035//response to inorganic substance;GO:0061519//macrophage homeostasis;GO:0035520//monoubiquitinated protein deubiquitination;GO:0016579//protein deubiquitination;GO:0051726//regulation of cell cycle;GO:0008285//negative regulation of cell proliferation","K08588//ubiquitin carboxyl-terminal hydrolase BAP1 [EC:3.4.19.12]","NP_004647.1//ubiquitin carboxyl-terminal hydrolase BAP1 [Homo sapiens]","3//A2MP1"]
[112937,2959,0.73,0.72,-0.0198995574377049,0.944215408100099,"*",0.897578,"GLB1L3","GO:0005773//vacuole","GO:0004565//beta-galactosidase activity","GO:0005975//carbohydrate metabolic process","K12309//beta-galactosidase [EC:3.2.1.23]","NP_001073876.2//beta-galactosidase-1-like protein 3 [Homo sapiens]","2//1"]
[90141,2626,6.58,6.49,-0.0198691057361029,0.831215542406857,"*",0.752798,"EFCAB11","NA","GO:0005509//calcium ion binding","NA","K16465//centrin-1;K07560//D-tyrosyl-tRNA(Tyr) deacylase [EC:3.1.-.-];K17985//activating molecule in BECN1-regulated autophagy protein 1;K02183//calmodulin;K12755//myosin regulatory light chain 9","NP_660274.1//EF-hand calcium-binding domain-containing protein 11 isoform 1 [Homo sapiens];NP_001271195.1//EF-hand calcium-binding domain-containing protein 11 isoform 2 [Homo sapiens];NP_001271198.1//EF-hand calcium-binding domain-containing protein 11 isoform 5 [Homo sapiens];NP_001271197.1//EF-hand calcium-binding domain-containing protein 11 isoform 4 [Homo sapiens]","1//3;3//A2MP1"]
[54552,8592,13.9,13.71,-0.0198563118316438,0.813171655408713,"*",0.728006,"GNL3L","GO:0016020//membrane;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005697//telomerase holoenzyme complex","GO:0003723//RNA binding;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0031397//negative regulation of protein ubiquitination;GO:0042254//ribosome biogenesis;GO:0090073//positive regulation of protein homodimerization activity;GO:0031647//regulation of protein stability;GO:0032091//negative regulation of protein binding;GO:1904816//positive regulation of protein localization to chromosome, telomeric region;GO:0032211//negative regulation of telomere maintenance via telomerase;GO:0033234//negative regulation of protein sumoylation","K14538//nuclear GTP-binding protein","NP_061940.1//guanine nucleotide-binding protein-like 3-like protein [Homo sapiens]","1//3;5"]
[339366,2867,3.66,3.61,-0.0198448113968717,0.956115405855,"*",0.913918,"ADAMTSL5","GO:0001527//microfibril;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix","GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding;GO:0008201//heparin binding","NA","K15686//RNA-binding protein MEX3 [EC:2.3.2.27];K08621//a disintegrin and metalloproteinase with thrombospondin motifs 6 [EC:3.4.24.-]","NP_998769.2//ADAMTS-like protein 5 precursor [Homo sapiens]","2//1"]
[10799,1105,16.89,16.66,-0.0197809274358381,0.920837862940785,"*",0.86642,"RPP40","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005655//nucleolar ribonuclease P complex","GO:0004526//ribonuclease P activity","GO:0001682//tRNA 5'-leader removal;GO:0006364//rRNA processing","K14530//ribonucleases P/MRP protein subunit RPP40 [EC:3.1.26.5]","NP_001273061.1//ribonuclease P protein subunit p40 isoform b [Homo sapiens];NP_001273062.1//ribonuclease P protein subunit p40 isoform c [Homo sapiens];NP_006629.2//ribonuclease P protein subunit p40 isoform a [Homo sapiens]","1//3;3//A2MP1"]
[29896,1931,31.59,31.16,-0.0197727036852038,0.628552320795773,"*",0.506336,"TRA2A","GO:0005730//nucleolus","GO:0003723//RNA binding","GO:0000398//mRNA splicing, via spliceosome","K12897//transformer-2 protein","XP_012369101.1//PREDICTED: transformer-2 protein homolog alpha [Octodon degus];XP_010639422.1//PREDICTED: transformer-2 protein homolog alpha isoform X1 [Fukomys damarensis];XP_008564754.1//PREDICTED: transformer-2 protein homolog alpha isoform X2 [Galeopterus variegatus]","4;1//3"]
[55217,2470,4.41,4.35,-0.0197632548214301,0.974982754670312,"*",0.93769,"TMLHE","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0050353//trimethyllysine dioxygenase activity;GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0005506//iron ion binding","GO:0045329//carnitine biosynthetic process;GO:0051354//negative regulation of oxidoreductase activity","K00474//trimethyllysine dioxygenase [EC:1.14.11.8]","NP_060666.1//trimethyllysine dioxygenase, mitochondrial isoform 1 precursor [Homo sapiens];NP_001171726.1//trimethyllysine dioxygenase, mitochondrial isoform 2 precursor [Homo sapiens]","1//3;3//A2MP1"]
[80039,2281,1.48,1.46,-0.0196288067489325,0.96118275689813,"*",0.920266,"FAM106A","NA","NA","NA","K02927//large subunit ribosomal protein L40e;K15696//RING finger protein 113B;K17985//activating molecule in BECN1-regulated autophagy protein 1","NP_079250.1//protein FAM106A [Homo sapiens]","2//1"]
[284613,4850,4.46,4.4,-0.019540186395645,0.956159793085385,"*",0.91414,"CYB561D1","GO:0016021//integral component of membrane","GO:0046872//metal ion binding","GO:0055114//oxidation-reduction process","K11318//ataxin-7;K08371//cytochrome b-561 domain containing protein 2","XP_017714281.1//PREDICTED: cytochrome b561 domain-containing protein 1 isoform X1 [Rhinopithecus bieti];XP_011539589.2//PREDICTED: cytochrome b561 domain-containing protein 1 isoform X1 [Homo sapiens];XP_017830488.1//PREDICTED: LOW QUALITY PROTEIN: cytochrome b561 domain-containing protein 1 [Callithrix jacchus];EAW56387.1//hCG2043250, isoform CRA_b [Homo sapiens];NP_001127874.1//cytochrome b561 domain-containing protein 1 isoform 3 [Homo sapiens]","1//3;2//1"]
[55374,1866,9.7,9.57,-0.0194658225884644,0.755454666955392,"*",0.655194,"TMCO6","GO:0005634//nucleus;GO:0016021//integral component of membrane;GO:0005737//cytoplasm","GO:0008565//protein transporter activity","GO:0006606//protein import into nucleus","K15043//importin subunit alpha-2","NP_060972.3//transmembrane and coiled-coil domain-containing protein 6 isoform 2 [Homo sapiens];NP_001287909.1//transmembrane and coiled-coil domain-containing protein 6 isoform 1 [Homo sapiens];XP_004042703.2//PREDICTED: transmembrane and coiled-coil domain-containing protein 6 isoform X3 [Gorilla gorilla gorilla]","4;1//3"]
[122616,1908,5.98,5.9,-0.0194305299489014,0.959779876210416,"*",0.918322,"CLBA1","NA","NA","NA","NA","NP_777551.2//uncharacterized protein C14orf79 [Homo sapiens]","3//A2MP1"]
[9946,1726,3.74,3.69,-0.0194174538272407,0.982007380559704,"*",0.946782,"CRYZL1","NA","NA","NA","K10133//tumor protein p53-inducible protein 3 [EC:1.-.-.-]","XP_012602486.1//quinone oxidoreductase-like protein 1 isoform X1 [Microcebus murinus]","2//1"]
[8536,1500,12.74,12.57,-0.0193806278357926,0.951119195323788,"*",0.906582,"CAMK1","NA","NA","NA","K08794//calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]","XP_017820551.1//PREDICTED: LOW QUALITY PROTEIN: calcium/calmodulin-dependent protein kinase type 1 [Callithrix jacchus]",4]
[8602,3672,23.24,22.93,-0.0193737138237354,0.851788612817181,"*",0.779642,"NOP14","GO:0016020//membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0030686//90S preribosome;GO:0030692//Noc4p-Nop14p complex;GO:0005730//nucleolus;GO:0032040//small-subunit processome;GO:0005739//mitochondrion","GO:0030515//snoRNA binding;GO:0003723//RNA binding;GO:0019899//enzyme binding","GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000472//endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0042274//ribosomal small subunit biogenesis;GO:0000447//endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006364//rRNA processing;GO:0030490//maturation of SSU-rRNA;GO:0000480//endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)","K14766//nucleolar protein 14","NP_001278908.1//nucleolar protein 14 isoform 2 [Homo sapiens];AAB97011.1//unknown protein IT12, partial [Homo sapiens]","1//3;2//1"]
[5298,4035,16.5,16.28,-0.0193653248669311,0.212164150167805,"*",0.1147684,"PI4KB","GO:0016020//membrane;GO:0005768//endosome;GO:0030867//rough endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005741//mitochondrial outer membrane;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0000139//Golgi membrane","GO:0071889//14-3-3 protein binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0004430//1-phosphatidylinositol 4-kinase activity","GO:0007165//signal transduction;GO:0006898//receptor-mediated endocytosis;GO:0048015//phosphatidylinositol-mediated signaling;GO:0006661//phosphatidylinositol biosynthetic process;GO:0046854//phosphatidylinositol phosphorylation","K19801//phosphatidylinositol 4-kinase B [EC:2.7.1.67]","NP_002642.1//phosphatidylinositol 4-kinase beta isoform 1 [Homo sapiens];EDL38764.1//phosphatidylinositol 4-kinase, catalytic, beta polypeptide, isoform CRA_c, partial [Mus musculus];ERE90758.1//phosphatidylinositol 4-kinase beta isoform 2 [Cricetulus griseus];XP_005245321.1//PREDICTED: phosphatidylinositol 4-kinase beta isoform X6 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[51074,1285,19.52,19.26,-0.0193453497194269,0.939342922152526,"*",0.890594,"APIP","GO:0005737//cytoplasm","GO:0042802//identical protein binding;GO:0008270//zinc ion binding;GO:0046570//methylthioribulose 1-phosphate dehydratase activity","GO:0070269//pyroptosis;GO:0051289//protein homotetramerization;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0019284//L-methionine salvage from S-adenosylmethionine;GO:0043066//negative regulation of apoptotic process;GO:0019509//L-methionine salvage from methylthioadenosine;GO:0006915//apoptotic process","K08964//methylthioribulose-1-phosphate dehydratase [EC:4.2.1.109]","NP_057041.2//methylthioribulose-1-phosphate dehydratase [Homo sapiens]","3//A2MP1"]
[5440,971,58.44,57.67,-0.019135155746378,0.896034492045378,"*",0.835622,"POLR2K","NA","NA","NA","K03009//DNA-directed RNA polymerases I, II, and III subunit RPABC4","XP_004011861.2//PREDICTED: DNA-directed RNA polymerases I, II, and III subunit RPABC4 [Ovis aries]","3//A2MP1"]
[26010,6206,17.58,17.35,-0.0189994076777805,0.833710841828982,"*",0.755632,"SPATS2L","GO:0005634//nucleus;GO:0005730//nucleolus;GO:0043234//protein complex;GO:0005829//cytosol","GO:0003723//RNA binding","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K03211//ETS translocation variant 6/7;K04487//cysteine desulfurase [EC:2.8.1.7]","XP_016859273.1//PREDICTED: SPATS2-like protein isoform X3 [Homo sapiens];XP_011829931.1//PREDICTED: SPATS2-like protein isoform X2 [Mandrillus leucophaeus];NP_001269673.1//SPATS2-like protein isoform d [Homo sapiens]","1//3;2//1"]
[3783,2240,13.8,13.62,-0.0189415636534605,0.929883377005702,"*",0.877958,"KCNN4","GO:0031982//vesicle;GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0043025//neuronal cell body","GO:0015269//calcium-activated potassium channel activity;GO:0005267//potassium channel activity;GO:0019903//protein phosphatase binding;GO:0005516//calmodulin binding;GO:0016286//small conductance calcium-activated potassium channel activity","GO:0006813//potassium ion transport;GO:0006884//cell volume homeostasis;GO:0046541//saliva secretion;GO:0030322//stabilization of membrane potential;GO:0006816//calcium ion transport;GO:0050714//positive regulation of protein secretion;GO:0002376//immune system process;GO:0045332//phospholipid translocation;GO:0006952//defense response;GO:0050862//positive regulation of T cell receptor signaling pathway","K04945//potassium intermediate/small conductance calcium-activated channel subfamily N member 4","XP_012302172.1//intermediate conductance calcium-activated potassium channel protein 4 isoform X1 [Aotus nancymaae]","2//1"]
[54472,3633,19.17,18.92,-0.0189382483287554,0.90184584986272,"*",0.843074,"TOLLIP","GO:0070062//extracellular exosome;GO:0035580//specific granule lumen;GO:0045092//interleukin-18 receptor complex;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0035578//azurophil granule lumen;GO:0005829//cytosol;GO:0045323//interleukin-1 receptor complex;GO:0016604//nuclear body;GO:0005576//extracellular region","GO:0031625//ubiquitin protein ligase binding;GO:0031624//ubiquitin conjugating enzyme binding;GO:0035325//Toll-like receptor binding;GO:0005150//interleukin-1, Type I receptor binding;GO:0043130//ubiquitin binding;GO:0019900//kinase binding;GO:0004871//signal transducer activity;GO:0032183//SUMO binding","GO:0036010//protein localization to endosome;GO:0016310//phosphorylation;GO:0007165//signal transduction;GO:0045321//leukocyte activation;GO:0007267//cell-cell signaling;GO:0035556//intracellular signal transduction;GO:0033235//positive regulation of protein sumoylation;GO:0006954//inflammatory response;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006914//autophagy;GO:0043312//neutrophil degranulation;GO:0045087//innate immune response;GO:0030855//epithelial cell differentiation","K05402//toll-interacting protein","NP_001305441.1//toll-interacting protein isoform 2 [Homo sapiens];NP_061882.2//toll-interacting protein isoform 1 [Homo sapiens];NP_001305445.1//toll-interacting protein isoform 4 [Homo sapiens];BAD92778.1//toll interacting protein variant, partial [Homo sapiens]","1//3;3//A2MP1"]
[285381,4046,5.39,5.32,-0.0188590272513157,0.932769048937157,"*",0.881792,"DPH3","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0046872//metal ion binding","GO:0017183//peptidyl-diphthamide biosynthetic process from peptidyl-histidine;GO:0050709//negative regulation of protein secretion;GO:0051099//positive regulation of binding","K15455//diphthamide biosynthesis protein 3","XP_011929659.1//PREDICTED: LOW QUALITY PROTEIN: putative DPH3 homolog B, partial [Cercocebus atys]","2//1"]
[27090,1710,24.67,24.35,-0.0188359433304186,0.909793606358111,"*",0.852782,"ST6GALNAC4","GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0047290//(alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity;GO:0008373//sialyltransferase activity;GO:0001665//alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity","GO:0006664//glycolipid metabolic process;GO:0006486//protein glycosylation;GO:0018279//protein N-linked glycosylation via asparagine;GO:0009311//oligosaccharide metabolic process;GO:0016266//O-glycan processing","K03374//N-acetylgalactosaminide alpha-2,6-sialyltransferase (sialyltransferase 7D) [EC:2.4.99.7]","XP_011516829.1//PREDICTED: alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase isoform X1 [Homo sapiens];NP_778204.1//alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase isoform a [Homo sapiens]","3//A2MP1"]
[58496,774,17.07,16.85,-0.0187144669585172,0.96402411809275,"*",0.923952,"LY6G5B","GO:0043234//protein complex;GO:0005576//extracellular region","GO:0042802//identical protein binding","GO:0051260//protein homooligomerization","K20005//lymphocyte antigen 6 complex locus protein G5","NP_067044.2//lymphocyte antigen 6 complex locus protein G5b precursor [Homo sapiens]","2//1"]
[10432,5415,49.78,49.14,-0.018668372618871,0.758125625270446,"*",0.65808,"RBM14","GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005667//transcription factor complex;GO:0016592//mediator complex;GO:0030529//intracellular ribonucleoprotein complex;GO:0016607//nuclear speck;GO:0005737//cytoplasm","GO:0003723//RNA binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0030674//protein binding, bridging;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity","GO:0030520//intracellular estrogen receptor signaling pathway;GO:0006281//DNA repair;GO:0006260//DNA replication;GO:0002218//activation of innate immune response;GO:0006351//transcription, DNA-templated;GO:0042921//glucocorticoid receptor signaling pathway;GO:0060395//SMAD protein signal transduction;GO:0098534//centriole assembly;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0009725//response to hormone;GO:0046600//negative regulation of centriole replication;GO:0006310//DNA recombination;GO:0016575//histone deacetylation;GO:0045087//innate immune response","K13187//RNA-binding protein 4;K13189//RNA-binding protein 14","NP_001185766.1//RNA-binding protein 14 isoform 3 [Homo sapiens];NP_001185765.1//RNA-binding protein 14 isoform 2 [Homo sapiens];NP_006319.1//RNA-binding protein 14 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[100129924,3354,3.12,3.08,-0.0186156781673471,0.997020630855958,"*",0.963254,"TMEM269","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein;K10858//DNA mismatch repair protein PMS2;K01064//wingless-type MMTV integration site family, member 9","NP_001341531.1//transmembrane protein 269 [Homo sapiens]","1//3"]
[51021,2651,54.05,53.36,-0.0185359514374275,0.834175472172352,"*",0.756262,"MRPS16","GO:0005840//ribosome;GO:0005829//cytosol;GO:0005763//mitochondrial small ribosomal subunit;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0003735//structural constituent of ribosome","GO:0032543//mitochondrial translation;GO:0006412//translation;GO:0070126//mitochondrial translational termination;GO:0070125//mitochondrial translational elongation","K02959//small subunit ribosomal protein S16","NP_057149.1//28S ribosomal protein S16, mitochondrial [Homo sapiens]","3//A2MP1"]
[9741,1783,126.29,124.68,-0.0185103468913739,0.782863052683826,"*",0.691168,"LAPTM4A","GO:0016021//integral component of membrane","NA","NA","K12387//lysosomal-associated transmembrane protein","EDM03082.1//lysosomal-associated protein transmembrane 4A [Rattus norvegicus]",4]
[10569,3570,11.01,10.87,-0.0184625285370599,0.92509391699316,"*",0.872104,"SLU7","NA","NA","NA","K12819//pre-mRNA-processing factor SLU7","XP_004404827.1//PREDICTED: pre-mRNA-splicing factor SLU7 [Odobenus rosmarus divergens]",4]
[7150,3750,27.64,27.29,-0.018385221114118,0.861418143382854,"*",0.791314,"TOP1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0000932//P-body;GO:0009330//DNA topoisomerase complex (ATP-hydrolyzing);GO:0043204//perikaryon;GO:0005730//nucleolus;GO:0031298//replication fork protection complex;GO:0001650//fibrillar center;GO:0032993//protein-DNA complex","GO:0003723//RNA binding;GO:0003677//DNA binding;GO:0003917//DNA topoisomerase type I activity;GO:0001046//core promoter sequence-specific DNA binding;GO:0005524//ATP binding;GO:0003690//double-stranded DNA binding;GO:0003697//single-stranded DNA binding;GO:0019904//protein domain specific binding;GO:0004674//protein serine/threonine kinase activity;GO:0097100//supercoiled DNA binding;GO:0003682//chromatin binding","GO:0007623//circadian rhythm;GO:0042493//response to drug;GO:0016925//protein sumoylation;GO:0016310//phosphorylation;GO:0007059//chromosome segregation;GO:0006338//chromatin remodeling;GO:0006260//DNA replication;GO:0016032//viral process;GO:0040016//embryonic cleavage;GO:0018105//peptidyl-serine phosphorylation;GO:0012501//programmed cell death;GO:0032922//circadian regulation of gene expression;GO:0006265//DNA topological change","K03163//DNA topoisomerase I [EC:5.99.1.2]","NP_003277.1//DNA topoisomerase 1 [Homo sapiens]","3//A2MP1"]
[10365,2814,7.17,7.08,-0.0182237586189073,0.954120494656088,"*",0.910936,"KLF2","GO:0000790//nuclear chromatin","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0003676//nucleic acid binding","GO:0071409//cellular response to cycloheximide;GO:0071498//cellular response to fluid shear stress;GO:0032715//negative regulation of interleukin-6 production;GO:0071356//cellular response to tumor necrosis factor;GO:0045893//positive regulation of transcription, DNA-templated;GO:0071499//cellular response to laminar fluid shear stress;GO:0071347//cellular response to interleukin-1;GO:0070301//cellular response to hydrogen peroxide;GO:0000902//cell morphogenesis;GO:0040029//regulation of gene expression, epigenetic;GO:0043249//erythrocyte maturation;GO:0051247//positive regulation of protein metabolic process;GO:1901653//cellular response to peptide;GO:0006351//transcription, DNA-templated;GO:0001701//in utero embryonic development;GO:0036003//positive regulation of transcription from RNA polymerase II promoter in response to stress;GO:0035264//multicellular organism growth;GO:0060509//Type I pneumocyte differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045429//positive regulation of nitric oxide biosynthetic process","K17845//krueppel-like factor 2","NP_057354.1//Krueppel-like factor 2 [Homo sapiens]","3//A2MP1"]
[64114,2330,70.23,69.35,-0.0181915526222041,0.831782927914852,"*",0.753416,"TMBIM1","GO:0005765//lysosomal membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0010008//endosome membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0035579//specific granule membrane;GO:0005886//plasma membrane","GO:0005123//death receptor binding","GO:1903077//negative regulation of protein localization to plasma membrane;GO:2000504//positive regulation of blood vessel remodeling;GO:0043312//neutrophil degranulation;GO:0043086//negative regulation of catalytic activity;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:1902045//negative regulation of Fas signaling pathway","K06890//uncharacterized protein","BAG62294.1//unnamed protein product [Homo sapiens];NP_071435.2//protein lifeguard 3 isoform 1 [Homo sapiens]","1//3;5"]
[2558,2820,38.84,38.36,-0.0179404804010615,0.742991166739099,"*",0.642152,"GABRA5","GO:0030425//dendrite;GO:0044297//cell body;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0045202//synapse;GO:0005886//plasma membrane","GO:0005230//extracellular ligand-gated ion channel activity;GO:0004890//GABA-A receptor activity","GO:0060384//innervation;GO:0007214//gamma-aminobutyric acid signaling pathway;GO:0043524//negative regulation of neuron apoptotic process;GO:0001662//behavioral fear response;GO:0006821//chloride transport;GO:0008306//associative learning;GO:0060119//inner ear receptor cell development;GO:0007605//sensory perception of sound;GO:0090102//cochlea development","K05175//gamma-aminobutyric acid receptor subunit alpha","XP_012419323.1//PREDICTED: gamma-aminobutyric acid receptor subunit alpha-5 isoform X1 [Odobenus rosmarus divergens]","1//3;3//A2MP1"]
[51118,2067,38.08,37.61,-0.0179171722676371,0.883381939631305,"*",0.818956,"UTP11","GO:0005654//nucleoplasm;GO:0005615//extracellular space;GO:0032040//small-subunit processome;GO:0005730//nucleolus;GO:0019013//viral nucleocapsid;GO:0005737//cytoplasm","GO:0003723//RNA binding","GO:0007399//nervous system development;GO:0043065//positive regulation of apoptotic process;GO:0042274//ribosomal small subunit biogenesis;GO:0006364//rRNA processing","K14769//U3 small nucleolar RNA-associated protein 11","NP_057121.2//probable U3 small nucleolar RNA-associated protein 11 [Homo sapiens]","3//A2MP1"]
[116835,3072,2.44,2.41,-0.0178480013329246,0.942283843121746,"*",0.894916,"HSPA12B","NA","GO:0005524//ATP binding","NA","K10609//cullin 4;K22016//mucin-3/17","XP_018872826.1//PREDICTED: heat shock 70 kDa protein 12B isoform X1 [Gorilla gorilla gorilla];AAH90857.1//HSPA12B protein, partial [Homo sapiens]","4;1//3"]
[10953,2066,35.14,34.71,-0.0177628261797299,0.889554813139472,"*",0.827296,"TOMM34","GO:0016020//membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005741//mitochondrial outer membrane","GO:0031072//heat shock protein binding","GO:0006626//protein targeting to mitochondrion","K17766//mitochondrial import receptor subunit TOM34","NP_006800.2//mitochondrial import receptor subunit TOM34 [Homo sapiens]",4]
[22846,6030,3.27,3.23,-0.0177564708041576,0.953720623417514,"*",0.910196,"VASH1","GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0045177//apical part of cell;GO:0005737//cytoplasm","NA","GO:0009611//response to wounding;GO:0001937//negative regulation of endothelial cell proliferation;GO:0060716//labyrinthine layer blood vessel development;GO:0001525//angiogenesis;GO:0010596//negative regulation of endothelial cell migration;GO:0016525//negative regulation of angiogenesis;GO:0007050//cell cycle arrest;GO:0045765//regulation of angiogenesis;GO:1901491//negative regulation of lymphangiogenesis;GO:2000772//regulation of cellular senescence;GO:0043537//negative regulation of blood vessel endothelial cell migration","K16628//collagen, type VII, alpha","NP_055724.1//vasohibin-1 [Homo sapiens]",4]
[79084,2423,34.43,34.01,-0.0177071748620737,0.68633292014807,"*",0.568736,"WDR77","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0034709//methylosome;GO:0005737//cytoplasm","GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0016274//protein-arginine N-methyltransferase activity;GO:0008327//methyl-CpG binding","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0060770//negative regulation of epithelial cell proliferation involved in prostate gland development;GO:0060528//secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development;GO:0000387//spliceosomal snRNP assembly;GO:0008284//positive regulation of cell proliferation","K13221//methylosome protein 50","NP_001303993.1//methylosome protein 50 isoform 4 [Homo sapiens];NP_077007.1//methylosome protein 50 isoform 2 [Homo sapiens];NP_001303991.1//methylosome protein 50 isoform 1 [Homo sapiens];NP_001303992.1//methylosome protein 50 isoform 3 [Homo sapiens]","1//3;3//A2MP1"]
[5495,3231,11.5,11.36,-0.0176710263270555,0.299034305069519,"*",0.1750326,"PPM1B","GO:0016020//membrane;GO:0005730//nucleolus;GO:0005829//cytosol","GO:0000287//magnesium ion binding;GO:0004722//protein serine/threonine phosphatase activity;GO:0030145//manganese ion binding","GO:0035970//peptidyl-threonine dephosphorylation;GO:0042347//negative regulation of NF-kappaB import into nucleus;GO:0006499//N-terminal protein myristoylation;GO:0006470//protein dephosphorylation;GO:0032688//negative regulation of interferon-beta production;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0050687//negative regulation of defense response to virus","K04461//protein phosphatase 1B [EC:3.1.3.16]","NP_001028729.1//protein phosphatase 1B isoform 5 [Homo sapiens];NP_808907.1//protein phosphatase 1B isoform 2 [Homo sapiens];NP_002697.1//protein phosphatase 1B isoform 1 [Homo sapiens]","3//A2MP1;2//1;5"]
[5284,4295,0.83,0.82,-0.0174874267288411,1.02199214101573,"*",0.99269,"PIGR","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0043235//receptor complex;GO:0035577//azurophil granule membrane","GO:0001792//polymeric immunoglobulin receptor activity","GO:0043113//receptor clustering;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0001895//retina homeostasis;GO:0043312//neutrophil degranulation;GO:0002415//immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor;GO:0038093//Fc receptor signaling pathway;GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste","K13073//polymeric immunoglobulin receptor","NP_002635.2//polymeric immunoglobulin receptor precursor [Homo sapiens]","3//A2MP1"]
[152185,5280,2.52,2.49,-0.0172779914318355,0.966095924538155,"*",0.926482,"SPICE1","GO:0005814//centriole;GO:0005819//spindle;GO:0005813//centrosome","NA","GO:0090307//mitotic spindle assembly;GO:0051301//cell division;GO:0051310//metaphase plate congression;GO:0046599//regulation of centriole replication","K16490//spindle and centriole-associated protein 1","NP_001318008.1//spindle and centriole-associated protein 1 isoform b [Homo sapiens];XP_016861265.1//PREDICTED: spindle and centriole-associated protein 1 isoform X2 [Homo sapiens]","1//3;3//A2MP1"]
[51155,1612,152.95,151.14,-0.0171745789901674,0.781338089509894,"*",0.689626,"JPT1","GO:0005634//nucleus;GO:0031965//nuclear membrane;GO:0005730//nucleolus;GO:0005737//cytoplasm","NA","NA","NA","XP_009189479.2//jupiter microtubule associated homolog 1 isoform X1 [Papio anubis];XP_008511468.1//PREDICTED: hematological and neurological expressed 1 protein isoform X1 [Equus przewalskii];EAW89245.1//hematological and neurological expressed 1, isoform CRA_b [Homo sapiens];NP_001002032.1//jupiter microtubule associated homolog 1 isoform 2 [Homo sapiens];XP_014337755.1//PREDICTED: hematological and neurological expressed 1 protein isoform X1 [Bos mutus];XP_017740254.1//PREDICTED: hematological and neurological expressed 1 protein isoform X1 [Rhinopithecus bieti]","1//3;3//A2MP1;2//1"]
[113878,2662,39.83,39.36,-0.0171252590249461,0.94480055642561,"*",0.898844,"DTX2","GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0005737//cytoplasm","GO:0008270//zinc ion binding;GO:0016740//transferase activity","GO:0016567//protein ubiquitination;GO:0007219//Notch signaling pathway","K06058//deltex [EC:2.3.2.27]","NP_001096066.1//probable E3 ubiquitin-protein ligase DTX2 isoform b [Homo sapiens];XP_014988767.1//PREDICTED: probable E3 ubiquitin-protein ligase DTX2 isoform X1 [Macaca mulatta];XP_011785482.1//PREDICTED: probable E3 ubiquitin-protein ligase DTX2 isoform X1 [Colobus angolensis palliatus]","1//3;2//1"]
[2962,2551,32.3,31.92,-0.0170735133589412,0.901502991490787,"*",0.842302,"GTF2F1","GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005674//transcription factor TFIIF complex;GO:0043234//protein complex;GO:0030054//cell junction;GO:0005669//transcription factor TFIID complex","GO:0003723//RNA binding;GO:0003677//DNA binding;GO:0003713//transcription coactivator activity;GO:0019904//protein domain specific binding;GO:0019211//phosphatase activator activity;GO:0019903//protein phosphatase binding;GO:0008134//transcription factor binding","GO:0016070//RNA metabolic process;GO:0042795//snRNA transcription from RNA polymerase II promoter;GO:0000398//mRNA splicing, via spliceosome;GO:0006370//7-methylguanosine mRNA capping;GO:0050434//positive regulation of viral transcription;GO:0006366//transcription from RNA polymerase II promoter;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0009615//response to virus","K03138//transcription initiation factor TFIIF subunit alpha","NP_002087.2//general transcription factor IIF subunit 1 [Homo sapiens]","2//1"]
[64423,4296,55.38,54.73,-0.0170331971594422,0.473637909191176,"*",0.322598,"INF2","GO:0048471//perinuclear region of cytoplasm","GO:0003779//actin binding;GO:0017048//Rho GTPase binding","GO:0030036//actin cytoskeleton organization;GO:0090140//regulation of mitochondrial fission","K01939//adenylosuccinate synthase [EC:6.3.4.4];K04512//dishevelled associated activator of morphogenesis;K05741//diaphanous 2","XP_005268061.1//PREDICTED: inverted formin-2 isoform X1 [Homo sapiens];XP_005268062.1//PREDICTED: inverted formin-2 isoform X2 [Homo sapiens]","3//A2MP1;2//1"]
[6627,1103,51.12,50.52,-0.0170331971594419,0.912563873324888,"*",0.856864,"SNRPA1","GO:0005654//nucleoplasm;GO:0005686//U2 snRNP;GO:0016607//nuclear speck;GO:0071013//catalytic step 2 spliceosome;GO:0005681//spliceosomal complex;GO:0030532//small nuclear ribonucleoprotein complex;GO:0030529//intracellular ribonucleoprotein complex;GO:0019013//viral nucleocapsid","GO:0030620//U2 snRNA binding;GO:0003723//RNA binding","GO:0006397//mRNA processing;GO:0000398//mRNA splicing, via spliceosome;GO:0008380//RNA splicing;GO:0035722//interleukin-12-mediated signaling pathway","K11092//U2 small nuclear ribonucleoprotein A'","XP_014998567.1//PREDICTED: U2 small nuclear ribonucleoprotein A' isoform X1 [Macaca mulatta]","3//A2MP1"]
[81929,2855,18.11,17.9,-0.0168269587985492,0.747902217655572,"*",0.647052,"SEH1L","GO:0005765//lysosomal membrane;GO:0043657//host cell;GO:0005635//nuclear envelope;GO:0061700//GATOR2 complex;GO:0005829//cytosol;GO:0031080//nuclear pore outer ring;GO:0000777//condensed chromosome kinetochore;GO:0000776//kinetochore","NA","GO:0006406//mRNA export from nucleus;GO:0007077//mitotic nuclear envelope disassembly;GO:0034198//cellular response to amino acid starvation;GO:0016925//protein sumoylation;GO:0006999//nuclear pore organization;GO:0006110//regulation of glycolytic process;GO:0032008//positive regulation of TOR signaling;GO:0051028//mRNA transport;GO:0007080//mitotic metaphase plate congression;GO:0050830//defense response to Gram-positive bacterium;GO:0015031//protein transport;GO:1904263//positive regulation of TORC1 signaling;GO:0051315//attachment of mitotic spindle microtubules to kinetochore;GO:0060964//regulation of gene silencing by miRNA;GO:0006409//tRNA export from nucleus;GO:0034629//cellular protein complex localization;GO:0016032//viral process;GO:0002534//cytokine production involved in inflammatory response;GO:1900034//regulation of cellular response to heat;GO:0007062//sister chromatid cohesion;GO:0051301//cell division;GO:0019083//viral transcription;GO:0075733//intracellular transport of virus","K14299//nucleoporin SEH1","NP_001013455.1//nucleoporin SEH1 isoform 1 [Homo sapiens];NP_112493.2//nucleoporin SEH1 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[118812,2367,6.05,5.98,-0.0167896579638516,1.00588007043895,"*",0.972632,"MORN4","GO:0032426//stereocilium tip;GO:0005737//cytoplasm;GO:0032433//filopodium tip","NA","GO:0048678//response to axon injury","K19755//radial spoke head protein 1;K12581//CCR4-NOT transcription complex subunit 7/8;K19530//junctophilin","EGV99291.1//MORN repeat-containing protein 4 [Cricetulus griseus]","1//3;3//A2MP1"]
[6793,6039,6.95,6.87,-0.0167028787927697,0.930002955392059,"*",0.878362,"STK10","GO:0070062//extracellular exosome;GO:0035579//specific granule membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity","GO:0023014//signal transduction by protein phosphorylation;GO:0071593//lymphocyte aggregation;GO:0007346//regulation of mitotic cell cycle;GO:0006468//protein phosphorylation;GO:0032147//activation of protein kinase activity;GO:2000401//regulation of lymphocyte migration;GO:0046777//protein autophosphorylation;GO:0043312//neutrophil degranulation;GO:0031098//stress-activated protein kinase signaling cascade;GO:0007049//cell cycle;GO:0042981//regulation of apoptotic process","K08837//serine/threonine kinase 10 [EC:2.7.11.1]","NP_005981.3//serine/threonine-protein kinase 10 [Homo sapiens]","3//A2MP1"]
[92856,3082,47.04,46.5,-0.0166573439536082,0.81591406196477,"*",0.733628,"IMP4","GO:0005654//nucleoplasm;GO:0032040//small-subunit processome;GO:0005730//nucleolus;GO:0034457//Mpp10 complex;GO:0001650//fibrillar center","GO:0030515//snoRNA binding;GO:0042134//rRNA primary transcript binding","GO:0006364//rRNA processing","K14561//U3 small nucleolar ribonucleoprotein protein IMP4","XP_003281794.1//PREDICTED: U3 small nucleolar ribonucleoprotein protein IMP4 [Nomascus leucogenys];XP_010371582.1//PREDICTED: U3 small nucleolar ribonucleoprotein protein IMP4 isoform X2 [Rhinopithecus roxellana];EAW55615.1//IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast), isoform CRA_c [Homo sapiens]","1//3;2//1"]
[79762,2990,2.64,2.61,-0.0164881227885691,0.988450941443486,"*",0.954232,"C1orf115","GO:0016021//integral component of membrane","NA","NA","K05740//diaphanous 1;K05747//Wiskott-Aldrich syndrome protein;K10367//formin 1","XP_001172852.3//PREDICTED: uncharacterized protein C1orf115 homolog [Pan troglodytes]",4]
[2298,2204,0.88,0.87,-0.0164881227885689,0.939334049907579,"*",0.890762,"FOXD4","GO:0005634//nucleus","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity;GO:0008301//DNA binding, bending","GO:0009653//anatomical structure morphogenesis;GO:0030154//cell differentiation;GO:0006351//transcription, DNA-templated","K09397//forkhead box protein D","AAQ76878.1//FOXD4 [Homo sapiens]",4]
[149175,2674,22.89,22.63,-0.0164808782887942,0.758616474268416,"*",0.658886,"MANEAL","GO:0016021//integral component of membrane;GO:0000139//Golgi membrane","GO:0016798//hydrolase activity, acting on glycosyl bonds","NA","K15538//glycoprotein endo-alpha-1,2-mannosidase [EC:3.2.1.130]","XP_011761821.1//PREDICTED: glycoprotein endo-alpha-1,2-mannosidase-like protein isoform X2 [Macaca nemestrina];NP_001026910.1//glycoprotein endo-alpha-1,2-mannosidase-like protein isoform 1 precursor [Homo sapiens];NP_001106954.1//glycoprotein endo-alpha-1,2-mannosidase-like protein isoform 3 precursor [Homo sapiens]","1//3;2//1"]
[6428,3144,63.59,62.87,-0.0164281457152403,0.823983020612117,"*",0.743256,"SRSF3","NA","NA","NA","K12892//splicing factor, arginine/serine-rich 3","OCT91642.1//hypothetical protein XELAEV_18014700mg [Xenopus laevis]",4]
[6487,2283,1.77,1.75,-0.0163944382506686,0.850852372443046,"*",0.778572,"ST3GAL3","GO:0032580//Golgi cisterna membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0000139//Golgi membrane","GO:0003836//beta-galactoside (CMP) alpha-2,3-sialyltransferase activity;GO:0008373//sialyltransferase activity;GO:0008118//N-acetyllactosaminide alpha-2,3-sialyltransferase activity","GO:0006486//protein glycosylation;GO:0018146//keratan sulfate biosynthetic process;GO:0018279//protein N-linked glycosylation via asparagine;GO:0009311//oligosaccharide metabolic process;GO:0016266//O-glycan processing","K00781//neolactotetraosylceramide alpha-2,3-sialyltransferase (sialyltransferase 6) [EC:2.4.99.6]","NP_001257390.1//CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform m [Homo sapiens];NP_777626.1//CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform d [Homo sapiens];XP_012577841.1//PREDICTED: CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X5 [Condylura cristata];NP_001257391.1//CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform n [Homo sapiens];NP_777629.1//CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform g [Homo sapiens];NP_777628.2//CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform f [Homo sapiens];NP_001337548.1//CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform s [Homo sapiens];NP_001257394.1//CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform q [Homo sapiens];NP_001257395.1//CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform r [Homo sapiens];XP_011540276.1//PREDICTED: CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X3 [Homo sapiens];NP_777631.2//CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform i [Homo sapiens];NP_001257388.1//CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform k [Homo sapiens];NP_777623.2//CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform a [Homo sapiens];NP_001257389.1//CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform l [Homo sapiens];XP_012577840.1//PREDICTED: CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X4 [Condylura cristata];NP_006270.1//CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform j [Homo sapiens];NP_777624.1//CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform b [Homo sapiens];NP_001257392.1//CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform o [Homo sapiens];NP_001257393.1//CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform p [Homo sapiens];NP_001337549.1//CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform t [Homo sapiens]","4;1//3;3//A2MP1;2//1"]
[55471,2068,11.51,11.38,-0.0163872758256483,0.983494165228114,"*",0.948708,"NDUFAF7","GO:0005759//mitochondrial matrix;GO:0005615//extracellular space;GO:0005739//mitochondrion","GO:0008168//methyltransferase activity;GO:0035243//protein-arginine omega-N symmetric methyltransferase activity;GO:0019899//enzyme binding","GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0046034//ATP metabolic process;GO:0019918//peptidyl-arginine methylation, to symmetrical-dimethyl arginine","K18164//NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 7","NP_001336956.1//protein arginine methyltransferase NDUFAF7, mitochondrial isoform 6 [Homo sapiens];NP_001336953.1//protein arginine methyltransferase NDUFAF7, mitochondrial isoform 4 [Homo sapiens];NP_001077415.1//protein arginine methyltransferase NDUFAF7, mitochondrial isoform 3 [Homo sapiens];NP_653337.1//protein arginine methyltransferase NDUFAF7, mitochondrial isoform 1 [Homo sapiens];NP_001336954.1//protein arginine methyltransferase NDUFAF7, mitochondrial isoform 5 [Homo sapiens]","4;1//3"]
[23383,4853,7.97,7.88,-0.0163840945340956,0.924452540188654,"*",0.87121,"MAU2","NA","NA","NA","K11266//MAternally affected uncoordination","XP_017356856.1//PREDICTED: MAU2 chromatid cohesion factor homolog isoform X1 [Cebus capucinus imitator]","3//A2MP1"]
[10055,2486,138.26,136.7,-0.0163705878137576,0.543364568231489,"*",0.389104,"SAE1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031510//SUMO activating enzyme complex;GO:0005737//cytoplasm","GO:0008022//protein C-terminus binding;GO:0046982//protein heterodimerization activity;GO:0043008//ATP-dependent protein binding;GO:0044388//small protein activating enzyme binding;GO:0008047//enzyme activator activity;GO:0004839//ubiquitin activating enzyme activity","GO:0016925//protein sumoylation;GO:1903955//positive regulation of protein targeting to mitochondrion;GO:0016567//protein ubiquitination","K10684//ubiquitin-like 1-activating enzyme E1 A [EC:6.2.1.45]","XP_016791806.1//PREDICTED: SUMO-activating enzyme subunit 1 isoform X1 [Pan troglodytes];XP_011825127.1//PREDICTED: SUMO-activating enzyme subunit 1 isoform X1 [Mandrillus leucophaeus];XP_016791809.1//PREDICTED: SUMO-activating enzyme subunit 1 isoform X4 [Pan troglodytes]","1//3;2//1"]
[5725,3335,180.17,178.14,-0.0163473096936379,0.713562485390579,"*",0.599296,"PTBP1","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus","GO:0003723//RNA binding;GO:0036002//pre-mRNA binding;GO:0008187//poly-pyrimidine tract binding","GO:0016070//RNA metabolic process;GO:0006397//mRNA processing;GO:0075522//IRES-dependent viral translational initiation;GO:0000398//mRNA splicing, via spliceosome;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0033119//negative regulation of RNA splicing;GO:0051148//negative regulation of muscle cell differentiation;GO:0008380//RNA splicing;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0048025//negative regulation of mRNA splicing, via spliceosome","K13218//polypyrimidine tract-binding protein 1","NP_114367.1//polypyrimidine tract-binding protein 1 isoform b [Homo sapiens];NP_002810.1//polypyrimidine tract-binding protein 1 isoform a [Homo sapiens];NP_114368.1//polypyrimidine tract-binding protein 1 isoform c [Homo sapiens]","4;3//A2MP1"]
[25970,3204,26.77,26.47,-0.0162589441453793,0.187855905140962,"*",0.0992788,"SH2B1","GO:0016020//membrane;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005622//intracellular","GO:0035591//signaling adaptor activity;GO:0004871//signal transducer activity","GO:0030032//lamellipodium assembly;GO:0007165//signal transduction;GO:0007596//blood coagulation;GO:2000278//regulation of DNA biosynthetic process;GO:0035556//intracellular signal transduction;GO:0045840//positive regulation of mitotic nuclear division","K12459//SH2B adaptor protein 1/3","XP_015297999.1//PREDICTED: SH2B adapter protein 1 isoform X1 [Macaca fascicularis];NP_001139284.1//SH2B adapter protein 1 isoform 2 [Homo sapiens];XP_012320016.1//SH2B adapter protein 1 isoform X2 [Aotus nancymaae];XP_012320020.1//SH2B adapter protein 1 isoform X4 [Aotus nancymaae];XP_012320015.1//SH2B adapter protein 1 isoform X1 [Aotus nancymaae]","1//3;2//1"]
[100506581,1094,3.57,3.53,-0.0162558907579192,0.840264719565068,"*",0.76436,"C16orf95","NA","NA","NA","NA","NP_001182053.1//uncharacterized protein C16orf95 isoform 1 [Homo sapiens];XP_007992480.1//PREDICTED: uncharacterized protein C16orf95 homolog isoform X7 [Chlorocebus sabaeus];NP_001182054.1//uncharacterized protein C16orf95 isoform 2 [Homo sapiens]","1//3"]
[9343,4096,74.21,73.38,-0.0162267024527462,0.700939263575762,"*",0.585842,"EFTUD2","GO:0016020//membrane;GO:0031012//extracellular matrix;GO:0005654//nucleoplasm;GO:0016607//nuclear speck;GO:0046540//U4/U6 x U5 tri-snRNP complex;GO:0071013//catalytic step 2 spliceosome;GO:0005681//spliceosomal complex;GO:0030529//intracellular ribonucleoprotein complex;GO:0005829//cytosol;GO:0015030//Cajal body;GO:0019013//viral nucleocapsid","GO:0003723//RNA binding;GO:0003746//translation elongation factor activity;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0006397//mRNA processing;GO:0000398//mRNA splicing, via spliceosome;GO:0035690//cellular response to drug;GO:0008380//RNA splicing;GO:0042220//response to cocaine","K12852//116 kDa U5 small nuclear ribonucleoprotein component","NP_001245283.1//116 kDa U5 small nuclear ribonucleoprotein component isoform c [Homo sapiens];XP_011795512.1//PREDICTED: 116 kDa U5 small nuclear ribonucleoprotein component isoform X1 [Colobus angolensis palliatus];NP_004238.3//116 kDa U5 small nuclear ribonucleoprotein component isoform a [Homo sapiens]","1//3;3//A2MP1"]
[2101,2287,24.33,24.06,-0.0160996777623527,0.930590828893307,"*",0.879092,"ESRRA","NA","NA","NA","K08552//estrogen-related receptor alpha","XP_007992093.1//PREDICTED: steroid hormone receptor ERR1 isoform X1 [Chlorocebus sabaeus]","1//3;4"]
[7982,2505,13.54,13.39,-0.016071778250686,1.01044567997412,"*",0.977616,"ST7","GO:0016021//integral component of membrane","NA","NA","K09291//nucleoprotein TPR","NP_068708.1//suppressor of tumorigenicity 7 protein isoform b [Homo sapiens];NP_060882.2//suppressor of tumorigenicity 7 protein isoform a [Homo sapiens]","3//A2MP1;2//1"]
[51603,3233,16.42,16.24,-0.0159024945926288,0.474125692293561,"*",0.323138,"METTL13","NA","GO:0008168//methyltransferase activity","NA","K01415//endothelin-converting enzyme [EC:3.4.24.71];K08513//vesicle-associated membrane protein 4","BAD97213.1//KIAA0859 protein (Fragment) variant, partial [Homo sapiens];NP_057019.3//methyltransferase-like protein 13 isoform 1 [Homo sapiens];NP_001007240.1//methyltransferase-like protein 13 isoform 3 [Homo sapiens]","4;1//3;2//1"]
[80013,2367,6.52,6.45,-0.015572803920461,0.972286631222309,"*",0.934184,"MINDY3","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane","GO:0016807//cysteine-type carboxypeptidase activity;GO:0036459//thiol-dependent ubiquitinyl hydrolase activity;GO:1990380//Lys48-specific deubiquitinase activity","GO:0006915//apoptotic process","K08742//E3 ubiquitin-protein ligase SIAH2 [EC:2.3.2.27];K20465//oxysterol-binding protein-related protein 9/10/11","NP_079224.1//ubiquitin carboxyl-terminal hydrolase MINDY-3 isoform a [Homo sapiens];CAG33596.1//FLJ13397 [Homo sapiens]","1//3;3//A2MP1"]
[80347,2574,81.45,80.58,-0.0154928932642816,0.862748288729997,"*",0.79313,"COASY","GO:0005759//mitochondrial matrix;GO:0070062//extracellular exosome;GO:0005741//mitochondrial outer membrane","GO:0005524//ATP binding;GO:0004140//dephospho-CoA kinase activity;GO:0004595//pantetheine-phosphate adenylyltransferase activity","GO:0009108//coenzyme biosynthetic process;GO:0015937//coenzyme A biosynthetic process","K02318//phosphopantetheine adenylyltransferase / dephospho-CoA kinase [EC:2.7.7.3 2.7.1.24]","NP_001035997.2//bifunctional coenzyme A synthase isoform c [Homo sapiens]","6;3//A2MP1;2//1"]
[65080,1772,27.29,27,-0.0154129873359473,0.937799177325581,"*",0.888602,"MRPL44","GO:0005840//ribosome;GO:0005634//nucleus;GO:0005762//mitochondrial large ribosomal subunit;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0005886//plasma membrane","GO:0003723//RNA binding;GO:0004525//ribonuclease III activity;GO:0003725//double-stranded RNA binding","GO:0006396//RNA processing;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic;GO:0070126//mitochondrial translational termination;GO:0070125//mitochondrial translational elongation","K17425//large subunit ribosomal protein L44 [EC:3.1.26.-]","NP_075066.1//39S ribosomal protein L44, mitochondrial [Homo sapiens]","3//A2MP1"]
[143903,2382,0.95,0.94,-0.0152667566533105,0.946890910382011,"*",0.901544,"LAYN","GO:0001726//ruffle;GO:0009986//cell surface;GO:0005925//focal adhesion;GO:0016021//integral component of membrane","GO:0030246//carbohydrate binding;GO:0005540//hyaluronic acid binding","NA","K10077//layilin","NP_849156.1//layilin isoform 2 precursor [Homo sapiens];NP_001245320.1//layilin isoform 3 [Homo sapiens];NP_001245319.1//layilin isoform 1 precursor [Homo sapiens]","1//3;4"]
[55325,2379,6.66,6.59,-0.0152437120632105,0.972860813285575,"*",0.935162,"UFSP2","GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005737//cytoplasm","GO:0071567//UFM1 hydrolase activity;GO:0016790//thiolester hydrolase activity","GO:0006508//proteolysis;GO:0033146//regulation of intracellular estrogen receptor signaling pathway","K01376//UFM1-specific protease 2 [EC:3.4.22.-]","XP_012640380.2//ufm1-specific protease 2 isoform X1 [Microcebus murinus]","3//A2MP1"]
[55245,2460,15.26,15.1,-0.0152064126220892,0.941181001978109,"*",0.893574,"UQCC1","GO:0031410//cytoplasmic vesicle;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","NA","GO:0034551//mitochondrial respiratory chain complex III assembly;GO:0070131//positive regulation of mitochondrial translation","K17662//cytochrome b pre-mRNA-processing protein 3","NP_955781.2//ubiquinol-cytochrome-c reductase complex assembly factor 1 isoform b [Homo sapiens];NP_001171906.1//ubiquinol-cytochrome-c reductase complex assembly factor 1 isoform c [Homo sapiens];NP_060714.3//ubiquinol-cytochrome-c reductase complex assembly factor 1 isoform a [Homo sapiens]","4;1//3;2//1"]
[7917,3662,65.03,64.35,-0.015165275332193,0.847260697071531,"*",0.773376,"BAG6","GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0071818//BAT3 complex;GO:0005829//cytosol","GO:0043022//ribosome binding;GO:0031593//polyubiquitin modification-dependent protein binding;GO:0042802//identical protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0005102//receptor binding;GO:1990381//ubiquitin-specific protease binding;GO:0051787//misfolded protein binding;GO:0070628//proteasome binding;GO:0030544//Hsp70 protein binding","GO:0030324//lung development;GO:0018393//internal peptidyl-lysine acetylation;GO:1904378//maintenance of unfolded protein involved in ERAD pathway;GO:0045861//negative regulation of proteolysis;GO:0001822//kidney development;GO:0042127//regulation of cell proliferation;GO:1904379//protein localization to cytosolic proteasome complex involved in ERAD pathway;GO:0002429//immune response-activating cell surface receptor signaling pathway;GO:0007283//spermatogenesis;GO:0007420//brain development;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0010498//proteasomal protein catabolic process;GO:0006810//transport;GO:0030154//cell differentiation;GO:0061857//endoplasmic reticulum stress-induced pre-emptive quality control;GO:0071712//ER-associated misfolded protein catabolic process;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0043066//negative regulation of apoptotic process;GO:0006915//apoptotic process;GO:0007130//synaptonemal complex assembly;GO:0030101//natural killer cell activation;GO:0016569//covalent chromatin modification;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0071816//tail-anchored membrane protein insertion into ER membrane;GO:1904294//positive regulation of ERAD pathway;GO:0009790//embryo development;GO:0050821//protein stabilization;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process","K19475//WAS/WASL-interacting protein;K05746//enabled","AAD18085.1//BAT3 [Homo sapiens];XP_008573291.1//PREDICTED: large proline-rich protein BAG6 isoform X2 [Galeopterus variegatus];NP_001186626.1//large proline-rich protein BAG6 isoform c [Homo sapiens];XP_017715016.1//PREDICTED: LOW QUALITY PROTEIN: large proline-rich protein BAG6 [Rhinopithecus bieti]","1//3;3//A2MP1;2//1"]
[55191,2453,19.25,19.05,-0.0150674480889417,0.937229350171912,"*",0.887358,"NADSYN1","GO:0005829//cytosol","GO:0005524//ATP binding;GO:0003952//NAD+ synthase (glutamine-hydrolyzing) activity;GO:0016810//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds","GO:0009435//NAD biosynthetic process","K01950//NAD+ synthase (glutamine-hydrolysing) [EC:6.3.5.1]","XP_003278076.1//PREDICTED: glutamine-dependent NAD(+) synthetase [Nomascus leucogenys]",4]
[22838,4153,22.31,22.08,-0.0149503414659716,0.899461713059802,"*",0.839888,"RNF44","NA","GO:0061630//ubiquitin protein ligase activity;GO:0046872//metal ion binding","GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process","K19041//E3 ubiquitin-protein ligase RNF38/44 [EC:2.3.2.27]","NP_055716.1//RING finger protein 44 [Homo sapiens]",4]
[9167,1163,92.34,91.39,-0.014919419835739,0.87359573541384,"*",0.80611,"COX7A2L","GO:0005730//nucleolus;GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0005746//mitochondrial respiratory chain","GO:0004129//cytochrome-c oxidase activity","GO:0006123//mitochondrial electron transport, cytochrome c to oxygen","K02270//cytochrome c oxidase subunit 7a","NP_001305966.1//cytochrome c oxidase subunit 7A-related protein, mitochondrial isoform b [Homo sapiens];XP_004770979.1//PREDICTED: cytochrome c oxidase subunit 7A-related protein, mitochondrial [Mustela putorius furo];EPQ06834.1//Cytochrome c oxidase subunit 7A-related protein, mitochondrial [Myotis brandtii]","1//3;3//A2MP1"]
[3551,4075,9.76,9.66,-0.0148579587271131,0.926339321385902,"*",0.873684,"IKBKB","GO:0005634//nucleus;GO:0045121//membrane raft;GO:0005829//cytosol;GO:0005622//intracellular;GO:0009898//cytoplasmic side of plasma membrane;GO:0035631//CD40 receptor complex;GO:0008385//IkappaB kinase complex","GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0019901//protein kinase binding;GO:0097110//scaffold protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0008384//IkappaB kinase activity;GO:0004672//protein kinase activity","GO:0042325//regulation of phosphorylation;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0030866//cortical actin cytoskeleton organization;GO:0070498//interleukin-1-mediated signaling pathway;GO:0071356//cellular response to tumor necrosis factor;GO:0010803//regulation of tumor necrosis factor-mediated signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0035509//negative regulation of myosin-light-chain-phosphatase activity;GO:0045087//innate immune response;GO:0009653//anatomical structure morphogenesis;GO:0072659//protein localization to plasma membrane;GO:0070423//nucleotide-binding oligomerization domain containing signaling pathway;GO:0050852//T cell receptor signaling pathway;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0002223//stimulatory C-type lectin receptor signaling pathway;GO:0006468//protein phosphorylation;GO:0043066//negative regulation of apoptotic process;GO:0006954//inflammatory response;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0018105//peptidyl-serine phosphorylation;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:1903347//negative regulation of bicellular tight junction assembly;GO:1903140//regulation of establishment of endothelial barrier;GO:0009615//response to virus;GO:0051403//stress-activated MAPK cascade","K07209//inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]","NP_001229707.1//inhibitor of nuclear factor kappa-B kinase subunit beta isoform 5 [Homo sapiens];NP_001547.1//inhibitor of nuclear factor kappa-B kinase subunit beta isoform 1 [Homo sapiens];NP_001177649.1//inhibitor of nuclear factor kappa-B kinase subunit beta isoform 2 [Homo sapiens]","1//3;2//1"]
[10961,1470,63.92,63.27,-0.0147458124131292,0.911626565327639,"*",0.855242,"ERP29","GO:0005790//smooth endoplasmic reticulum;GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005788//endoplasmic reticulum lumen;GO:0005783//endoplasmic reticulum;GO:0009986//cell surface;GO:0030133//transport vesicle;GO:0042470//melanosome","GO:0051087//chaperone binding;GO:0042803//protein homodimerization activity","GO:0006457//protein folding;GO:0050709//negative regulation of protein secretion;GO:0000187//activation of MAPK activity;GO:0010629//negative regulation of gene expression;GO:0010628//positive regulation of gene expression;GO:0043335//protein unfolding;GO:0006886//intracellular protein transport;GO:0009306//protein secretion;GO:1902235//regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway;GO:0001934//positive regulation of protein phosphorylation","K09586//endoplasmic reticulum protein 29","XP_003832503.1//PREDICTED: endoplasmic reticulum resident protein 29 isoform X1 [Pan paniscus];NP_006808.1//endoplasmic reticulum resident protein 29 isoform 1 precursor [Homo sapiens]","1//3;3//A2MP1"]
[1635,2173,28.74,28.45,-0.0146314092633921,0.952374640845533,"*",0.908196,"DCTD","GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0004132//dCMP deaminase activity;GO:0042802//identical protein binding;GO:0008270//zinc ion binding","GO:0006231//dTMP biosynthetic process;GO:0006220//pyrimidine nucleotide metabolic process;GO:0006226//dUMP biosynthetic process;GO:0015949//nucleobase-containing small molecule interconversion","K01493//dCMP deaminase [EC:3.5.4.12]","XP_517546.1//PREDICTED: deoxycytidylate deaminase isoform X2 [Pan troglodytes];XP_017404812.1//PREDICTED: deoxycytidylate deaminase isoform X1 [Cebus capucinus imitator]","1//3;2//1"]
[10749,7935,42.64,42.21,-0.014622608801487,0.796393545403271,"*",0.707152,"KIF1C","GO:0005783//endoplasmic reticulum;GO:0005874//microtubule;GO:0005794//Golgi apparatus;GO:0005871//kinesin complex","GO:0003723//RNA binding;GO:0005524//ATP binding;GO:0003774//motor activity;GO:0003777//microtubule motor activity;GO:0008017//microtubule binding;GO:0016887//ATPase activity","GO:0007018//microtubule-based movement;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0030705//cytoskeleton-dependent intracellular transport","K10392//kinesin family member 1","NP_006603.2//kinesin-like protein KIF1C [Homo sapiens]",5]
[51573,2935,39.97,39.57,-0.014510507447746,0.703183585959135,"*",0.588158,"GDE1","GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0030659//cytoplasmic vesicle membrane","GO:0004622//lysophospholipase activity;GO:0046872//metal ion binding;GO:0047395//glycerophosphoinositol glycerophosphodiesterase activity;GO:0008889//glycerophosphodiester phosphodiesterase activity","GO:0006644//phospholipid metabolic process;GO:0046475//glycerophospholipid catabolic process;GO:0070291//N-acylethanolamine metabolic process;GO:0006629//lipid metabolic process","K19179//glycerophosphoinositol glycerophosphodiesterase [EC:3.1.4.44]","NP_001310996.1//glycerophosphodiester phosphodiesterase 1 isoform 3 [Homo sapiens];NP_057725.1//glycerophosphodiester phosphodiesterase 1 isoform 1 [Homo sapiens];XP_014708948.1//PREDICTED: glycerophosphodiester phosphodiesterase 1 isoform X3 [Equus asinus]","1//3;3//A2MP1"]
[54977,2156,19.18,18.99,-0.0143628148686334,0.946044839876373,"*",0.90062,"SLC25A38","GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane","GO:0015187//glycine transmembrane transporter activity;GO:0005215//transporter activity","GO:0036233//glycine import;GO:0006839//mitochondrial transport;GO:0006783//heme biosynthetic process;GO:0030218//erythrocyte differentiation","K15118//solute carrier family 25, member 38","NP_060345.2//solute carrier family 25 member 38 isoform 1 [Homo sapiens];NP_001341727.1//solute carrier family 25 member 38 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[55650,2474,5.07,5.02,-0.0142983830525687,0.963524296596328,"*",0.923292,"PIGV","GO:0031501//mannosyltransferase complex;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0004376//glycolipid mannosyltransferase activity;GO:0000030//mannosyltransferase activity;GO:0004584//dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity","GO:0006506//GPI anchor biosynthetic process;GO:0016254//preassembly of GPI anchor in ER membrane","K07542//phosphatidylinositol glycan, class V [EC:2.4.1.-]","NP_060307.2//GPI mannosyltransferase 2 [Homo sapiens]","1//3;3//A2MP1"]
[83608,1057,10.15,10.05,-0.0142842260062476,0.997309100803317,"*",0.96372,"C18orf21","NA","NA","NA","NA","NP_001188405.1//UPF0711 protein C18orf21 isoform c [Homo sapiens];NP_113634.3//UPF0711 protein C18orf21 isoform a [Homo sapiens];AAH25950.2//C18orf21 protein, partial [Homo sapiens]","4;1//3"]
[79796,6197,4.07,4.03,-0.0142489557382796,0.845831425350564,"*",0.770324,"ALG9","GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0052918//dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity;GO:0000026//alpha-1,2-mannosyltransferase activity;GO:0016757//transferase activity, transferring glycosyl groups;GO:0052926//dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity;GO:0000030//mannosyltransferase activity","GO:0006486//protein glycosylation;GO:0006488//dolichol-linked oligosaccharide biosynthetic process","K03846//alpha-1,2-mannosyltransferase [EC:2.4.1.259 2.4.1.261]","XP_021782218.1//alpha-1,2-mannosyltransferase ALG9 isoform X7 [Papio anubis];NP_001071158.1//alpha-1,2-mannosyltransferase ALG9 isoform b [Homo sapiens];XP_014971160.1//PREDICTED: alpha-1,2-mannosyltransferase ALG9 isoform X1 [Macaca mulatta];XP_012325977.2//alpha-1,2-mannosyltransferase ALG9 isoform X4 [Aotus nancymaae];XP_008019018.1//PREDICTED: alpha-1,2-mannosyltransferase ALG9 isoform X6 [Chlorocebus sabaeus];NP_001339346.1//alpha-1,2-mannosyltransferase ALG9 isoform f [Homo sapiens];XP_012325975.1//alpha-1,2-mannosyltransferase ALG9 isoform X3 [Aotus nancymaae];NP_079016.2//alpha-1,2-mannosyltransferase ALG9 isoform a [Homo sapiens];NP_001339347.1//alpha-1,2-mannosyltransferase ALG9 isoform g [Homo sapiens];XP_016873802.1//PREDICTED: alpha-1,2-mannosyltransferase ALG9 isoform X4 [Homo sapiens];XP_005579650.1//PREDICTED: alpha-1,2-mannosyltransferase ALG9 isoform X3 [Macaca fascicularis]","1//3;2//1"]
[51107,2196,82.34,81.54,-0.0140854918327218,0.640112617654133,"*",0.49982,"APH1A","GO:0016021//integral component of membrane","NA","GO:0016485//protein processing;GO:0043085//positive regulation of catalytic activity","K06172//gamma-secretase subunit APH-1A","XP_002919359.2//PREDICTED: gamma-secretase subunit APH-1A [Ailuropoda melanoleuca];XP_004632461.1//PREDICTED: gamma-secretase subunit APH-1A isoform X4 [Octodon degus];XP_017516511.1//PREDICTED: gamma-secretase subunit APH-1A isoform X1 [Manis javanica];XP_004632460.1//PREDICTED: gamma-secretase subunit APH-1A isoform X2 [Octodon degus]","1//3;3//A2MP1;2//1"]
[54868,4763,15.48,15.33,-0.0140477744856328,0.977448353369763,"*",0.940612,"TMEM104","GO:0016021//integral component of membrane","NA","NA","K21125//mucin-5AC;K01069//hydroxyacylglutathione hydrolase [EC:3.1.2.6]","NP_001308193.1//transmembrane protein 104 isoform 2 [Homo sapiens];NP_060198.3//transmembrane protein 104 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[7484,2654,2.07,2.05,-0.0140068579938793,0.97787350962539,"*",0.941266,"WNT9B","GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix","GO:0048018//receptor ligand activity;GO:0005102//receptor binding;GO:0039706//co-receptor binding;GO:0005109//frizzled binding","GO:0009786//regulation of asymmetric cell division;GO:0009267//cellular response to starvation;GO:0072003//kidney rudiment formation;GO:0003339//regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis;GO:0001932//regulation of protein phosphorylation;GO:0030539//male genitalia development;GO:0001658//branching involved in ureteric bud morphogenesis;GO:1902455//negative regulation of stem cell population maintenance;GO:0060021//palate development;GO:0043085//positive regulation of catalytic activity;GO:0072181//mesonephric duct formation;GO:0061038//uterus morphogenesis;GO:0045165//cell fate commitment;GO:0072174//metanephric tubule formation;GO:1905438//non-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation;GO:0030182//neuron differentiation;GO:1904948//midbrain dopaminergic neuron differentiation;GO:0007267//cell-cell signaling;GO:0061303//cornea development in camera-type eye;GO:0001701//in utero embryonic development;GO:0032526//response to retinoic acid;GO:0072046//establishment of planar polarity involved in nephron morphogenesis;GO:0071300//cellular response to retinoic acid;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0060070//canonical Wnt signaling pathway;GO:0007275//multicellular organism development;GO:0016055//Wnt signaling pathway;GO:0035150//regulation of tube size;GO:0072044//collecting duct development;GO:0072038//mesenchymal stem cell maintenance involved in nephron morphogenesis","K01064//wingless-type MMTV integration site family, member 9","NP_003387.1//protein Wnt-9b isoform 1 precursor [Homo sapiens];NP_001307387.1//protein Wnt-9b isoform 2 precursor [Homo sapiens]","1//3;2//1"]
[51195,3709,4.14,4.1,-0.0140068579938793,1.00692766181135,"*",0.973708,"RAPGEFL1","GO:0005622//intracellular","GO:0005085//guanyl-nucleotide exchange factor activity","GO:0007264//small GTPase mediated signal transduction","K04351//Rap guanine nucleotide exchange factor 4","XP_014197529.1//PREDICTED: rap guanine nucleotide exchange factor-like 1 isoform X1 [Pan paniscus];NP_057423.2//rap guanine nucleotide exchange factor-like 1 isoform 3 [Homo sapiens];NP_001290463.1//rap guanine nucleotide exchange factor-like 1 isoform 2 [Homo sapiens]","1//3;2//1;5"]
[90485,2774,1.04,1.03,-0.0139391909578737,0.955352579440477,"*",0.91283,"ZNF835","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","EHH30446.1//hypothetical protein EGK_11119 [Macaca mulatta]","2//1"]
[54532,6612,2.11,2.09,-0.0137400566263024,0.968633687451083,"*",0.929704,"USP53","GO:0005911//cell-cell junction;GO:0005923//bicellular tight junction","GO:0036459//thiol-dependent ubiquitinyl hydrolase activity","GO:0010996//response to auditory stimulus;GO:0051402//neuron apoptotic process;GO:0007605//sensory perception of sound;GO:0001508//action potential;GO:0016579//protein deubiquitination","K14206//solute carrier family 15 (oligopeptide transporter), member 1","NP_061923.2//inactive ubiquitin carboxyl-terminal hydrolase 53 [Homo sapiens]","2//1"]
[445329,1397,27.69,27.43,-0.0136104315186531,0.961142713912134,"*",0.920348,"SULT1A4","GO:0005829//cytosol","GO:0004062//aryl sulfotransferase activity;GO:0008146//sulfotransferase activity;GO:0043199//sulfate binding;GO:0047685//amine sulfotransferase activity","GO:1901215//negative regulation of neuron death;GO:0006805//xenobiotic metabolic process;GO:0097720//calcineurin-mediated signaling;GO:0070371//ERK1 and ERK2 cascade;GO:0007212//dopamine receptor signaling pathway;GO:0042420//dopamine catabolic process;GO:0008202//steroid metabolic process;GO:0098989//NMDA selective glutamate receptor signaling pathway;GO:1903351//cellular response to dopamine;GO:0036498//IRE1-mediated unfolded protein response;GO:0051923//sulfation;GO:0009812//flavonoid metabolic process;GO:0006068//ethanol catabolic process;GO:0006584//catecholamine metabolic process;GO:0050427//3'-phosphoadenosine 5'-phosphosulfate metabolic process","K01014//aryl sulfotransferase [EC:2.8.2.1]","XP_005591701.1//PREDICTED: sulfotransferase 1A3 isoform X2 [Macaca fascicularis]","2//1"]
[1487,2353,52.68,52.19,-0.0134819436359957,0.740530528301887,"*",0.63882,"CTBP1","GO:0017053//transcriptional repressor complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription factor complex;GO:0005829//cytosol","GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0003714//transcription corepressor activity;GO:0042802//identical protein binding;GO:0070491//repressing transcription factor binding;GO:0051287//NAD binding;GO:0042803//protein homodimerization activity;GO:0001106//RNA polymerase II transcription corepressor activity;GO:0008022//protein C-terminus binding;GO:0019904//protein domain specific binding;GO:0008134//transcription factor binding;GO:0030267//glyoxylate reductase (NADP) activity;GO:0016618//hydroxypyruvate reductase activity;GO:0003700//DNA binding transcription factor activity","GO:0045892//negative regulation of transcription, DNA-templated;GO:0019079//viral genome replication;GO:1903758//negative regulation of transcription from RNA polymerase II promoter by histone modification;GO:0090241//negative regulation of histone H4 acetylation;GO:0050872//white fat cell differentiation;GO:0006468//protein phosphorylation;GO:0006351//transcription, DNA-templated;GO:0035067//negative regulation of histone acetylation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0031065//positive regulation of histone deacetylation;GO:0051726//regulation of cell cycle;GO:0008285//negative regulation of cell proliferation","K04496//C-terminal binding protein","NP_001012632.1//C-terminal-binding protein 1 isoform 2 [Homo sapiens];XP_008991975.1//PREDICTED: C-terminal-binding protein 1 isoform X2 [Callithrix jacchus]","1//3;2//1"]
[374659,955,41.27,40.89,-0.013345375480669,0.786925041557522,"*",0.695838,"HDDC3","NA","GO:0046872//metal ion binding;GO:0008893//guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity","NA","K21138//guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [EC:3.1.7.2]","NP_940929.1//guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 isoform 2 [Homo sapiens];NP_001273380.1//guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 isoform 1 [Homo sapiens]","1//3;4"]
[9410,1638,33.02,32.72,-0.0131673719715094,0.944261930843707,"*",0.897504,"SNRNP40","GO:0005654//nucleoplasm;GO:0005732//small nucleolar ribonucleoprotein complex;GO:0016607//nuclear speck;GO:0071013//catalytic step 2 spliceosome;GO:0005829//cytosol;GO:0030529//intracellular ribonucleoprotein complex;GO:0005682//U5 snRNP;GO:0071011//precatalytic spliceosome;GO:0019013//viral nucleocapsid","GO:0003723//RNA binding","GO:0006396//RNA processing;GO:0000398//mRNA splicing, via spliceosome;GO:0008380//RNA splicing;GO:0000375//RNA splicing, via transesterification reactions","K12857//Prp8 binding protein","XP_007977858.1//PREDICTED: U5 small nuclear ribonucleoprotein 40 kDa protein [Chlorocebus sabaeus]","2//1"]
[5468,3798,33.11,32.81,-0.0131314168785794,0.732958115555555,"*",0.629764,"PPARG","GO:0090575//RNA polymerase II transcription factor complex;GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005737//cytoplasm","GO:0003707//steroid hormone receptor activity;GO:0046982//protein heterodimerization activity;GO:0043621//protein self-association;GO:0003690//double-stranded DNA binding;GO:0050544//arachidonic acid binding;GO:0050693//LBD domain binding;GO:0050692//DBD domain binding;GO:0008144//drug binding;GO:0003682//chromatin binding;GO:0043565//sequence-specific DNA binding;GO:0008270//zinc ion binding;GO:0033613//activating transcription factor binding;GO:0042802//identical protein binding;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0042277//peptide binding;GO:0044212//transcription regulatory region DNA binding;GO:0004879//nuclear receptor activity;GO:0046965//retinoid X receptor binding;GO:0008022//protein C-terminus binding;GO:0051393//alpha-actinin binding;GO:0019899//enzyme binding","GO:0008217//regulation of blood pressure;GO:0010891//negative regulation of sequestering of triglyceride;GO:0031100//animal organ regeneration;GO:0042593//glucose homeostasis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0051091//positive regulation of DNA binding transcription factor activity;GO:0035357//peroxisome proliferator activated receptor signaling pathway;GO:0045713//low-density lipoprotein particle receptor biosynthetic process;GO:0042953//lipoprotein transport;GO:0043388//positive regulation of DNA binding;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0045165//cell fate commitment;GO:0060336//negative regulation of interferon-gamma-mediated signaling pathway;GO:0006351//transcription, DNA-templated;GO:0032526//response to retinoic acid;GO:0048511//rhythmic process;GO:0010887//negative regulation of cholesterol storage;GO:0032869//cellular response to insulin stimulus;GO:0048469//cell maturation;GO:0010745//negative regulation of macrophage derived foam cell differentiation;GO:0010871//negative regulation of receptor biosynthetic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0010742//macrophage derived foam cell differentiation;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0030224//monocyte differentiation","K08530//peroxisome proliferator-activated receptor gamma","NP_056953.2//peroxisome proliferator-activated receptor gamma isoform 2 [Homo sapiens];AAO66458.1//CREB3L2-PPARgamma [Homo sapiens];XP_011532145.1//PREDICTED: peroxisome proliferator-activated receptor gamma isoform X3 [Homo sapiens];NP_001341598.1//peroxisome proliferator-activated receptor gamma isoform 5 [Homo sapiens];NP_001341597.1//peroxisome proliferator-activated receptor gamma isoform 4 [Homo sapiens];XP_021550891.1//peroxisome proliferator-activated receptor gamma isoform X2 [Neomonachus schauinslandi]","4;1//3;3//A2MP1;5"]
[84256,4963,8.88,8.8,-0.0130561528254464,0.893178113471363,"*",0.831784,"FLYWCH1","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding","NA","K06237//collagen, type IV, alpha","NP_001294997.1//FLYWCH-type zinc finger-containing protein 1 isoform c [Homo sapiens];NP_115672.2//FLYWCH-type zinc finger-containing protein 1 isoform a [Homo sapiens]","1//3;2//1"]
[57567,4221,8.92,8.84,-0.0129973405288732,0.961191292486759,"*",0.920214,"ZNF319","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","NP_065858.1//zinc finger protein 319 [Homo sapiens]","2//1"]
[10491,6668,68.17,67.56,-0.012967654903874,0.798438942800789,"*",0.709568,"CRTAP","GO:0032991//macromolecular complex;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum","GO:0032403//protein complex binding","GO:0018400//peptidyl-proline hydroxylation to 3-hydroxy-L-proline;GO:1901874//negative regulation of post-translational protein modification;GO:0007283//spermatogenesis;GO:0050821//protein stabilization;GO:0061077//chaperone-mediated protein folding","K19606//cartilage-associated protein","XP_008007581.1//PREDICTED: LOW QUALITY PROTEIN: cartilage-associated protein [Chlorocebus sabaeus]",4]
[10603,2045,4.51,4.47,-0.0128526020720633,0.833234560928433,"*",0.755096,"SH2B2","GO:0001726//ruffle;GO:0005884//actin filament;GO:0001725//stress fiber;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0005070//SH3/SH2 adaptor activity;GO:0042802//identical protein binding;GO:0008269//JAK pathway signal transduction adaptor activity;GO:0005068//transmembrane receptor protein tyrosine kinase adaptor activity;GO:0004871//signal transducer activity","GO:0007399//nervous system development;GO:0030036//actin cytoskeleton organization;GO:0007165//signal transduction;GO:0008286//insulin receptor signaling pathway;GO:0007596//blood coagulation;GO:0035556//intracellular signal transduction;GO:0019222//regulation of metabolic process;GO:0001922//B-1 B cell homeostasis;GO:0046578//regulation of Ras protein signal transduction;GO:0050873//brown fat cell differentiation;GO:0019221//cytokine-mediated signaling pathway;GO:0050851//antigen receptor-mediated signaling pathway","K07193//SH2B adapter protein 2","XP_005277032.1//PREDICTED: SH2B adapter protein 2 isoform X1 [Homo sapiens];XP_011514042.1//PREDICTED: SH2B adapter protein 2 isoform X3 [Homo sapiens];NP_066189.3//SH2B adapter protein 2 [Homo sapiens]","1//3;4"]
[9878,4493,25.68,25.46,-0.0124127832209451,0.975150109867222,"*",0.937912,"TOX4","GO:0000784//nuclear chromosome, telomeric region;GO:0005634//nucleus;GO:0072357//PTW/PP1 phosphatase complex;GO:0000785//chromatin","GO:0003677//DNA binding","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K09272//structure-specific recognition protein 1;K18808//toll-like receptor 13","NP_055643.1//TOX high mobility group box family member 4 isoform 1 [Homo sapiens];NP_001290452.1//TOX high mobility group box family member 4 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[26156,5137,55.44,54.97,-0.0122827780994522,0.857159296351961,"*",0.78547,"RSL1D1","GO:0016020//membrane;GO:0030686//90S preribosome;GO:0005730//nucleolus","GO:0003723//RNA binding;GO:0048027//mRNA 5'-UTR binding;GO:0003730//mRNA 3'-UTR binding;GO:0045296//cadherin binding","GO:0000470//maturation of LSU-rRNA;GO:0001649//osteoblast differentiation;GO:0032880//regulation of protein localization;GO:2000772//regulation of cellular senescence;GO:0042981//regulation of apoptotic process","K14775//ribosome biogenesis protein UTP30","AAH19069.2//RSL1D1 protein, partial [Homo sapiens]","2//1"]
[283237,1130,15.36,15.23,-0.0122622742338639,0.884808328611898,"*",0.82122,"TTC9C","NA","NA","NA","K09571//FK506-binding protein 4/5 [EC:5.2.1.8];K09572//FK506-binding protein 6 [EC:5.2.1.8];K05864//peptidyl-prolyl isomerase D [EC:5.2.1.8]","EAW74086.1//tetratricopeptide repeat domain 9C, isoform CRA_a [Homo sapiens];AAL55789.1//unknown [Homo sapiens]","1//3;3//A2MP1"]
[84969,2464,7.13,7.07,-0.0121918616344892,0.94707440973044,"*",0.901778,"TOX2","GO:0005654//nucleoplasm","GO:0000978//RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0045944//positive regulation of transcription from RNA polymerase II promoter","K10955//mucin-2;K10802//high mobility group protein B1;K09272//structure-specific recognition protein 1;K18808//toll-like receptor 13","NP_001092267.1//TOX high mobility group box family member 2 isoform a [Homo sapiens];NP_001092268.1//TOX high mobility group box family member 2 isoform b [Homo sapiens]","1//3;2//1"]
[10482,2856,26.22,26,-0.0121560623059377,0.463547340484557,"*",0.31381,"NXF1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005643//nuclear pore;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0005737//cytoplasm;GO:0042405//nuclear inclusion body;GO:0000346//transcription export complex","GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0005487//nucleocytoplasmic transporter activity;GO:0003727//single-stranded RNA binding","GO:0016973//poly(A)+ mRNA export from nucleus;GO:0006406//mRNA export from nucleus;GO:0016032//viral process;GO:0006405//RNA export from nucleus","K14284//nuclear RNA export factor","XP_020031017.1//nuclear RNA export factor 1 [Castor canadensis];Q5R752.1//RecName: Full=Nuclear RNA export factor 1","4;1//3"]
[30011,4187,28.67,28.43,-0.0121278055629963,0.580711069296741,"*",0.423882,"SH3KBP1","GO:0005856//cytoskeleton;GO:0005925//focal adhesion;GO:0005737//cytoplasm;GO:0043005//neuron projection;GO:0030139//endocytic vesicle;GO:0005911//cell-cell junction;GO:0005829//cytosol;GO:0045202//synapse;GO:0005886//plasma membrane;GO:0030659//cytoplasmic vesicle membrane","GO:0016301//kinase activity;GO:0017124//SH3 domain binding","GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0016477//cell migration;GO:0007267//cell-cell signaling;GO:0008360//regulation of cell shape;GO:0061024//membrane organization;GO:0006915//apoptotic process;GO:0007010//cytoskeleton organization;GO:0006897//endocytosis;GO:0007411//axon guidance","K12470//SH3 domain-containing kinase-binding protein 1","NP_001340820.1//SH3 domain-containing kinase-binding protein 1 isoform e [Homo sapiens];NP_001171889.1//SH3 domain-containing kinase-binding protein 1 isoform c [Homo sapiens];NP_001340826.1//SH3 domain-containing kinase-binding protein 1 isoform j [Homo sapiens];NP_001340819.1//SH3 domain-containing kinase-binding protein 1 isoform d [Homo sapiens];XP_011543802.1//PREDICTED: SH3 domain-containing kinase-binding protein 1 isoform X6 [Homo sapiens];NP_114098.1//SH3 domain-containing kinase-binding protein 1 isoform a [Homo sapiens];NP_001340821.1//SH3 domain-containing kinase-binding protein 1 isoform f [Homo sapiens];NP_001019837.1//SH3 domain-containing kinase-binding protein 1 isoform b [Homo sapiens]","1//3;2//1"]
[144363,1149,8.4,8.33,-0.0120728323005751,0.99388946270011,"*",0.95998,"ETFRF1","GO:0005739//mitochondrion","NA","GO:0022904//respiratory electron transport chain","K00560//thymidylate synthase [EC:2.1.1.45];K20301//trafficking protein particle complex subunit 2;K11846//ubiquitin carboxyl-terminal hydrolase 18/41 [EC:3.4.19.12]","NP_001001660.2//electron transfer flavoprotein regulatory factor 1 [Homo sapiens]","2//1"]
[902,1415,26.43,26.21,-0.0120590713131523,0.979829302234927,"*",0.94413,"CCNH","GO:0005675//holo TFIIH complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0070985//TFIIK complex;GO:0019907//cyclin-dependent protein kinase activating kinase holoenzyme complex","GO:0008353//RNA polymerase II carboxy-terminal domain kinase activity;GO:0016301//kinase activity;GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity;GO:0008094//DNA-dependent ATPase activity","GO:0006361//transcription initiation from RNA polymerase I promoter;GO:0006370//7-methylguanosine mRNA capping;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0006362//transcription elongation from RNA polymerase I promoter;GO:0006363//termination of RNA polymerase I transcription;GO:1901409//positive regulation of phosphorylation of RNA polymerase II C-terminal domain;GO:0006468//protein phosphorylation;GO:0006351//transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter;GO:0006294//nucleotide-excision repair, preincision complex assembly;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0000082//G1/S transition of mitotic cell cycle;GO:0000086//G2/M transition of mitotic cell cycle;GO:0050821//protein stabilization;GO:0006367//transcription initiation from RNA polymerase II promoter","K06634//cyclin H","NP_001230.1//cyclin-H isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[57666,4563,20.73,20.56,-0.0118798519155368,0.927185231320504,"*",0.874714,"FBRSL1","NA","GO:0003723//RNA binding","NA","K16628//collagen, type VII, alpha","NP_001136113.1//fibrosin-1-like protein [Homo sapiens]","1//3"]
[5713,1686,70.9,70.32,-0.0118505569834746,0.920787227729359,"*",0.86643,"PSMD7","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005654//nucleoplasm;GO:0005838//proteasome regulatory particle","GO:0042803//protein homodimerization activity","NA","K03038//26S proteasome regulatory subunit N8","XP_008516632.1//PREDICTED: 26S proteasome non-ATPase regulatory subunit 7 [Equus przewalskii]",4]
[56906,2119,4.96,4.92,-0.0116818050476353,0.996956031877673,"*",0.963254,"THAP10","NA","GO:0046872//metal ion binding;GO:0003677//DNA binding","NA","K09228//KRAB domain-containing zinc finger protein;K09291//nucleoprotein TPR","NP_064532.1//THAP domain-containing protein 10 [Homo sapiens]","3//A2MP1"]
[3892,2256,41.5,41.17,-0.0115178878003801,0.937927775942929,"*",0.8889,"KRT86","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0045095//keratin filament","GO:0005198//structural molecule activity","GO:0031424//keratinization;GO:0070268//cornification","K07605//type II keratin, basic","XP_005268923.1//PREDICTED: keratin, type II cuticular Hb6 isoform X1 [Homo sapiens]","1//3"]
[51559,7214,6.36,6.31,-0.0113867603018066,0.971004311542723,"*",0.932648,"NT5DC3","GO:0043235//receptor complex","GO:0046872//metal ion binding;GO:0008253//5'-nucleotidase activity","NA","K01081//5'-nucleotidase [EC:3.1.3.5]","NP_001026871.1//5'-nucleotidase domain-containing protein 3 [Homo sapiens]","2//1"]
[10641,1672,11.48,11.39,-0.0113548949675759,0.97949786302794,"*",0.943688,"NPRL2","GO:0005765//lysosomal membrane;GO:1990130//GATOR1 complex","GO:0004672//protein kinase activity;GO:0005096//GTPase activator activity","GO:0032007//negative regulation of TOR signaling;GO:0034198//cellular response to amino acid starvation;GO:0033673//negative regulation of kinase activity","K20405//nitrogen permease regulator 2-like protein","XP_002813758.1//PREDICTED: nitrogen permease regulator 2-like protein [Pongo abelii]",4]
[138716,936,35.81,35.53,-0.0113248299893024,0.94208692023731,"*",0.89467,"RPP25L","NA","NA","NA","K14525//ribonucleases P/MRP protein subunit RPP25 [EC:3.1.26.5]","XP_003911616.2//ribonuclease P protein subunit p25-like protein isoform X1 [Papio anubis];XP_017747535.1//PREDICTED: ribonuclease P protein subunit p25-like protein isoform X1 [Rhinopithecus bieti]","2//1"]
[51385,3399,2.57,2.55,-0.0112711123350201,0.99174246596655,"*",0.95772,"ZNF589","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_009443668.1//PREDICTED: zinc finger protein 589 isoform X2 [Pan troglodytes]","2//1"]
[25983,1161,28.31,28.09,-0.0112551247793487,0.953554747572815,"*",0.909978,"NGDN","GO:0030425//dendrite;GO:0030424//axon;GO:0005634//nucleus;GO:0000775//chromosome, centromeric region;GO:0030175//filopodium;GO:0005730//nucleolus;GO:0032040//small-subunit processome;GO:0005739//mitochondrion","GO:0003723//RNA binding","GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006417//regulation of translation","K14765//U3 small nucleolar ribonucleoprotein protein LCP5","NP_001036100.1//neuroguidin isoform 1 [Homo sapiens];NP_056329.1//neuroguidin isoform 2 [Homo sapiens]","1//3"]
[10201,3079,5.15,5.11,-0.0112491411329594,1.0077461445674,"*",0.974878,"NME6","GO:0005829//cytosol;GO:0005739//mitochondrion","GO:0046872//metal ion binding;GO:0005524//ATP binding;GO:0004550//nucleoside diphosphate kinase activity","GO:0006228//UTP biosynthetic process;GO:0030308//negative regulation of cell growth;GO:0006241//CTP biosynthetic process;GO:0045839//negative regulation of mitotic nuclear division;GO:0015949//nucleobase-containing small molecule interconversion;GO:0006183//GTP biosynthetic process;GO:0006915//apoptotic process","K00940//nucleoside-diphosphate kinase [EC:2.7.4.6]","NP_005784.1//nucleoside diphosphate kinase 6 isoform 1 [Homo sapiens];XP_016861001.1//PREDICTED: nucleoside diphosphate kinase 6 isoform X2 [Homo sapiens];XP_016796506.1//PREDICTED: nucleoside diphosphate kinase 6 isoform X2 [Pan troglodytes];NP_001295359.1//nucleoside diphosphate kinase 6 isoform 3 [Homo sapiens];XP_009199120.1//nucleoside diphosphate kinase 6 isoform X1 [Papio anubis];XP_016796505.1//PREDICTED: nucleoside diphosphate kinase 6 isoform X1 [Pan troglodytes]","1//3;4"]
[22806,9045,2.59,2.57,-0.0111837384926758,0.912307326576877,"*",0.856566,"IKZF3","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005737//cytoplasm","GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity;GO:0044212//transcription regulatory region DNA binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0030888//regulation of B cell proliferation;GO:0007498//mesoderm development;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0045577//regulation of B cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0042981//regulation of apoptotic process;GO:0042113//B cell activation;GO:0045619//regulation of lymphocyte differentiation","K09228//KRAB domain-containing zinc finger protein;K09220//IKAROS family zinc finger protein","XP_006155969.1//PREDICTED: zinc finger protein Aiolos isoform X2 [Tupaia chinensis];NP_001244342.1//zinc finger protein Aiolos isoform 12 [Homo sapiens];NP_001244340.1//zinc finger protein Aiolos isoform 10 [Homo sapiens];XP_004041875.2//PREDICTED: zinc finger protein Aiolos isoform X3 [Gorilla gorilla gorilla];XP_004434617.2//PREDICTED: LOW QUALITY PROTEIN: zinc finger protein Aiolos [Ceratotherium simum simum];NP_899051.1//zinc finger protein Aiolos isoform 2 [Homo sapiens];NP_899052.1//zinc finger protein Aiolos isoform 3 [Homo sapiens];NP_899054.1//zinc finger protein Aiolos isoform 5 [Homo sapiens];XP_011592380.1//PREDICTED: zinc finger protein Aiolos [Aquila chrysaetos canadensis];CAC80428.1//AIOLOS isoform three [Homo sapiens];NP_001244341.1//zinc finger protein Aiolos isoform 11 [Homo sapiens];XP_004591209.1//PREDICTED: zinc finger protein Aiolos isoform X2 [Ochotona princeps];NP_001244343.1//zinc finger protein Aiolos isoform 13 [Homo sapiens];ELK01560.1//Zinc finger protein Aiolos [Pteropus alecto]","4;1//3;2//1"]
[6522,4036,148.26,147.12,-0.0111360316380027,0.637280216500425,"*",0.51596,"SLC4A2","GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005925//focal adhesion;GO:0016324//apical plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane","GO:0015301//anion:anion antiporter activity;GO:0008510//sodium:bicarbonate symporter activity;GO:0005452//inorganic anion exchanger activity;GO:0019899//enzyme binding;GO:0008509//anion transmembrane transporter activity","GO:0015701//bicarbonate transport;GO:0006820//anion transport;GO:0051453//regulation of intracellular pH;GO:0007283//spermatogenesis;GO:0048565//digestive tract development","K13855//solute carrier family 4 (anion exchanger), member 2","BAD92395.1//Anion exchanger 2 type a variant, partial [Homo sapiens];NP_001186622.1//anion exchange protein 2 isoform 2 [Homo sapiens];NP_001186623.1//anion exchange protein 2 isoform 3 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[51234,1031,78.27,77.67,-0.0111019789173408,0.939678562302006,"*",0.891324,"EMC4","GO:0072546//ER membrane protein complex;GO:0016021//integral component of membrane","NA","GO:0034975//protein folding in endoplasmic reticulum;GO:0006915//apoptotic process","K18203//[phosphatase 2A protein]-leucine-carboxy methyltransferase [EC:2.1.1.233]","NP_001273349.1//ER membrane protein complex subunit 4 isoform b [Homo sapiens];XP_006234766.1//PREDICTED: ER membrane protein complex subunit 4 isoform X2 [Rattus norvegicus];NP_057538.1//ER membrane protein complex subunit 4 isoform a [Homo sapiens]","1//3;3//A2MP1"]
[5859,2843,37.9,37.61,-0.0110815420181477,0.936708261852807,"*",0.886806,"QARS","GO:0005829//cytosol;GO:0017101//aminoacyl-tRNA synthetase multienzyme complex","GO:0004860//protein kinase inhibitor activity;GO:0005524//ATP binding;GO:0004819//glutamine-tRNA ligase activity;GO:0019901//protein kinase binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0007420//brain development;GO:0032873//negative regulation of stress-activated MAPK cascade;GO:2001234//negative regulation of apoptotic signaling pathway;GO:0006425//glutaminyl-tRNA aminoacylation","K01886//glutaminyl-tRNA synthetase [EC:6.1.1.18]","EAW64954.1//glutaminyl-tRNA synthetase, isoform CRA_b [Homo sapiens]","1//3;2//1"]
[1497,4431,13.22,13.12,-0.0109544568896081,0.98142720337772,"*",0.945854,"CTNS","NA","NA","NA","K12386//cystinosin","XP_008567055.1//PREDICTED: cystinosin isoform X2 [Galeopterus variegatus];XP_015361418.1//PREDICTED: cystinosin isoform X3 [Marmota marmota marmota]","2//1"]
[116113,5946,18.58,18.44,-0.0109118459533147,0.938841203803989,"*",0.889942,"FOXP4","GO:0005634//nucleus","GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0043565//sequence-specific DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0009653//anatomical structure morphogenesis;GO:0030154//cell differentiation;GO:0006351//transcription, DNA-templated","K09409//forkhead box protein P","NP_001012426.1//forkhead box protein P4 isoform 1 [Homo sapiens];NP_612466.1//forkhead box protein P4 isoform 2 [Homo sapiens];NP_001012427.1//forkhead box protein P4 isoform 3 [Homo sapiens]","1//3;2//1"]
[29775,3912,8.01,7.95,-0.0108473822369923,0.974001103457256,"*",0.936502,"CARD10","GO:0032449//CBM complex;GO:0005737//cytoplasm","GO:0030159//receptor signaling complex scaffold activity","GO:0007250//activation of NF-kappaB-inducing kinase activity;GO:0042981//regulation of apoptotic process;GO:0006461//protein complex assembly","K20912//caspase recruitment domain-containing protein 10","NP_055365.2//caspase recruitment domain-containing protein 10 [Homo sapiens]","3//A2MP1"]
[149466,1429,1.34,1.33,-0.0108067549565829,0.939272043567232,"*",0.890762,"C1orf210","GO:0016021//integral component of membrane;GO:0055037//recycling endosome;GO:0005886//plasma membrane;GO:0005769//early endosome","NA","NA","K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K02927//large subunit ribosomal protein L40e;K17985//activating molecule in BECN1-regulated autophagy protein 1","NP_872323.1//type III endosome membrane protein TEMP [Homo sapiens]","1//3;2//1"]
[50488,5030,45.62,45.28,-0.010792488480255,0.899166756068124,"*",0.8395,"MINK1","GO:0070062//extracellular exosome;GO:0030425//dendrite;GO:0030424//axon;GO:0030054//cell junction;GO:0014069//postsynaptic density;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0045211//postsynaptic membrane","GO:0004674//protein serine/threonine kinase activity;GO:0008349//MAP kinase kinase kinase kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity","GO:0046330//positive regulation of JNK cascade;GO:0001952//regulation of cell-matrix adhesion;GO:0007346//regulation of mitotic cell cycle;GO:0006950//response to stress;GO:0035556//intracellular signal transduction;GO:0030334//regulation of cell migration;GO:0048812//neuron projection morphogenesis;GO:0031098//stress-activated protein kinase signaling cascade;GO:0022407//regulation of cell-cell adhesion;GO:0031532//actin cytoskeleton reorganization;GO:0006468//protein phosphorylation;GO:2000311//regulation of AMPA receptor activity;GO:0048813//dendrite morphogenesis;GO:0007254//JNK cascade;GO:0046777//protein autophosphorylation;GO:0007275//multicellular organism development;GO:0007268//chemical synaptic transmission;GO:0042981//regulation of apoptotic process","K04413//misshapen/NIK-related kinase [EC:2.7.11.1]","NP_001020108.1//misshapen-like kinase 1 isoform 4 [Homo sapiens];NP_733763.1//misshapen-like kinase 1 isoform 2 [Homo sapiens];NP_056531.1//misshapen-like kinase 1 isoform 1 [Homo sapiens];NP_722549.2//misshapen-like kinase 1 isoform 3 [Homo sapiens]","1//3;4;3//A2MP1"]
[23404,1976,29.72,29.5,-0.0107191614020302,0.950011085556578,"*",0.90505,"EXOSC2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000176//nuclear exosome (RNase complex);GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0000177//cytoplasmic exosome (RNase complex);GO:0005829//cytosol;GO:0000178//exosome (RNase complex)","GO:0003723//RNA binding;GO:0000175//3'-5'-exoribonuclease activity;GO:0008312//7S RNA binding","GO:0043928//exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay;GO:0034427//nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5';GO:0030307//positive regulation of cell growth;GO:0071034//CUT catabolic process;GO:0006364//rRNA processing;GO:0071049//nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription;GO:0000467//exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0071035//nuclear polyadenylation-dependent rRNA catabolic process;GO:0043488//regulation of mRNA stability;GO:0071051//polyadenylation-dependent snoRNA 3'-end processing;GO:0034475//U4 snRNA 3'-end processing;GO:0071038//nuclear polyadenylation-dependent tRNA catabolic process","K03679//exosome complex component RRP4","NP_001269638.1//exosome complex component RRP4 isoform 3 [Homo sapiens];NP_001269637.1//exosome complex component RRP4 isoform 2 [Homo sapiens];OWK10071.1//EXOSC2, partial [Cervus elaphus hippelaphus]","6;1//3"]
[84305,1170,20.54,20.39,-0.0105744063015984,0.883046776066991,"*",0.81859,"PYM1","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0035145//exon-exon junction complex;GO:0030054//cell junction","GO:0043022//ribosome binding;GO:0003723//RNA binding","GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0045727//positive regulation of translation;GO:1903259//exon-exon junction complex disassembly","K14294//partner of Y14 and mago","NP_115721.1//partner of Y14 and mago isoform 1 [Homo sapiens];NP_001137325.1//partner of Y14 and mago isoform 2 [Homo sapiens]","1//3;2//1"]
[11154,3725,9.6,9.53,-0.0105581916985767,0.686324514881402,"*",0.568772,"AP4S1","GO:0032588//trans-Golgi network membrane;GO:0030124//AP-4 adaptor complex;GO:0005905//clathrin-coated pit;GO:0031904//endosome lumen","GO:0008565//protein transporter activity","GO:0006605//protein targeting","K12403//AP-4 complex subunit sigma-1","NP_001241655.1//AP-4 complex subunit sigma-1 isoform 3 [Homo sapiens];NP_001241656.1//AP-4 complex subunit sigma-1 isoform 4 [Homo sapiens];NP_009008.2//AP-4 complex subunit sigma-1 isoform 1 [Homo sapiens];XP_002718171.2//PREDICTED: AP-4 complex subunit sigma-1 isoform X2 [Oryctolagus cuniculus]","4;1//3;2//1"]
[10645,4491,12.5,12.41,-0.0104249794190927,0.778821904584794,"*",0.681652,"CAMKK2","GO:0005634//nucleus;GO:0042995//cell projection;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005737//cytoplasm","GO:0004713//protein tyrosine kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0004683//calmodulin-dependent protein kinase activity;GO:0005509//calcium ion binding;GO:0005516//calmodulin binding","GO:0045859//regulation of protein kinase activity;GO:0000165//MAPK cascade;GO:0034614//cellular response to reactive oxygen species;GO:0061762//CAMKK-AMPK signaling cascade;GO:0006468//protein phosphorylation;GO:1903599//positive regulation of autophagy of mitochondrion;GO:0019722//calcium-mediated signaling;GO:0046777//protein autophosphorylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0018107//peptidyl-threonine phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0001934//positive regulation of protein phosphorylation;GO:0045860//positive regulation of protein kinase activity","K07359//calcium/calmodulin-dependent protein kinase kinase 2 [EC:2.7.11.17]","NP_757365.1//calcium/calmodulin-dependent protein kinase kinase 2 isoform 3 [Homo sapiens];NP_705719.2//calcium/calmodulin-dependent protein kinase kinase 2 isoform 2 [Homo sapiens];NP_705720.1//calcium/calmodulin-dependent protein kinase kinase 2 isoform 4 [Homo sapiens];NP_757364.1//calcium/calmodulin-dependent protein kinase kinase 2 isoform 6 [Homo sapiens];XP_011803910.1//PREDICTED: calcium/calmodulin-dependent protein kinase kinase 2 isoform X1 [Colobus angolensis palliatus];NP_001257415.1//calcium/calmodulin-dependent protein kinase kinase 2 isoform 7 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[57026,2072,17,16.88,-0.010219842317879,0.978505396449704,"*",0.942058,"PDXP","GO:0070062//extracellular exosome;GO:0005856//cytoskeleton;GO:0032587//ruffle membrane;GO:0030027//lamellipodium;GO:0030496//midbody;GO:0031258//lamellipodium membrane;GO:0032154//cleavage furrow;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0070938//contractile ring","GO:0000287//magnesium ion binding;GO:0033883//pyridoxal phosphatase activity;GO:0004647//phosphoserine phosphatase activity;GO:0004721//phosphoprotein phosphatase activity;GO:0031072//heat shock protein binding;GO:0016791//phosphatase activity;GO:0098519//nucleotide phosphatase activity, acting on free nucleotides","GO:0032361//pyridoxal phosphate catabolic process;GO:0030836//positive regulation of actin filament depolymerization;GO:0071318//cellular response to ATP;GO:0006470//protein dephosphorylation;GO:0032465//regulation of cytokinesis;GO:0031247//actin rod assembly;GO:0007088//regulation of mitotic nuclear division","K07758//pyridoxal phosphatase [EC:3.1.3.74]","XP_003905563.2//pyridoxal phosphate phosphatase isoform X6 [Papio anubis]",4]
[29920,1630,59.63,59.21,-0.0101974830015464,1.02107637937456,"*",0.995444,"PYCR2","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0004735//pyrroline-5-carboxylate reductase activity","GO:0006561//proline biosynthetic process;GO:0055129//L-proline biosynthetic process;GO:0008652//cellular amino acid biosynthetic process;GO:0034599//cellular response to oxidative stress","K00286//pyrroline-5-carboxylate reductase [EC:1.5.1.2]","NP_037460.2//pyrroline-5-carboxylate reductase 2 isoform 1 [Homo sapiens];NP_001258610.1//pyrroline-5-carboxylate reductase 2 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[84650,978,37.09,36.83,-0.0101488706032719,0.978441774512354,"*",0.942058,"EBPL","GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0047750//cholestenol delta-isomerase activity","GO:0016125//sterol metabolic process","K11494//RCC1 and BTB domain-containing protein;K01824//cholestenol Delta-isomerase [EC:5.3.3.5]","NP_115954.1//emopamil-binding protein-like isoform 1 [Homo sapiens];NP_001265565.1//emopamil-binding protein-like isoform 2 [Homo sapiens]","1//3;4"]
[81618,2052,51.95,51.59,-0.0100323026389003,0.854030659282051,"*",0.781908,"ITM2C","GO:0005765//lysosomal membrane;GO:0070062//extracellular exosome;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005764//lysosome;GO:0005886//plasma membrane;GO:0048471//perinuclear region of cytoplasm","GO:0001540//amyloid-beta binding;GO:0005524//ATP binding","GO:0007399//nervous system development;GO:0030182//neuron differentiation;GO:0010977//negative regulation of neuron projection development;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:0042985//negative regulation of amyloid precursor protein biosynthetic process","K18265//integral membrane protein 2C","NP_001012532.1//integral membrane protein 2C isoform 3 [Homo sapiens];XP_001112946.2//PREDICTED: integral membrane protein 2C [Macaca mulatta]","1//3;2//1;5"]
[619208,2671,1.45,1.44,-0.00998408857262213,1.02192614620939,"*",0.99237,"FAM229B","NA","NA","NA","K01368//cathepsin S [EC:3.4.22.27];K10391//tubulin epsilon;K01064//wingless-type MMTV integration site family, member 9","NP_001028736.1//protein FAM229B [Homo sapiens]","2//1"]
[90139,4242,1.49,1.48,-0.00971515483321178,0.982071147272727,"*",0.946782,"TSPAN18","GO:0016021//integral component of membrane","NA","NA","K17353//tetraspanin-18","XP_009458554.1//PREDICTED: tetraspanin-18 isoform X1 [Pan troglodytes]",4]
[4291,2257,2.99,2.97,-0.00968255339733939,0.983381750519211,"*",0.948538,"MLF1","GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0019904//protein domain specific binding","GO:0002318//myeloid progenitor cell differentiation;GO:0006351//transcription, DNA-templated;GO:0007050//cell cycle arrest","K15622//myeloid leukemia factor 1","NP_001182362.1//myeloid leukemia factor 1 isoform 4 [Homo sapiens];NP_071888.1//myeloid leukemia factor 1 isoform 1 [Homo sapiens];XP_005247536.1//PREDICTED: myeloid leukemia factor 1 isoform X1 [Homo sapiens];NP_001182361.1//myeloid leukemia factor 1 isoform 3 [Homo sapiens]","4;1//3;2//1"]
[64897,2793,13.58,13.49,-0.0095931312964642,0.961219812250768,"*",0.920482,"C12orf43","NA","NA","NA","K12581//CCR4-NOT transcription complex subunit 7/8;K04613//vomeronasal 2 receptor;K01064//wingless-type MMTV integration site family, member 9","NP_001273121.1//uncharacterized protein C12orf43 isoform b [Homo sapiens];NP_001273125.1//uncharacterized protein C12orf43 isoform e [Homo sapiens];NP_001273127.1//uncharacterized protein C12orf43 isoform g [Homo sapiens];NP_001273120.1//uncharacterized protein C12orf43 isoform a [Homo sapiens];NP_075046.1//uncharacterized protein C12orf43 isoform c [Homo sapiens];NP_001273124.1//uncharacterized protein C12orf43 isoform d [Homo sapiens];NP_001273126.1//uncharacterized protein C12orf43 isoform f [Homo sapiens]","1//3;2//1"]
[5828,4388,4.55,4.52,-0.00954377267087103,1.01389612620418,"*",0.981716,"PEX2","GO:0005779//integral component of peroxisomal membrane;GO:0016593//Cdc73/Paf1 complex","GO:0046872//metal ion binding","GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0000038//very long-chain fatty acid metabolic process;GO:0006635//fatty acid beta-oxidation;GO:0016558//protein import into peroxisome matrix;GO:0050680//negative regulation of epithelial cell proliferation;GO:0031648//protein destabilization;GO:0048147//negative regulation of fibroblast proliferation","K06664//peroxin-2","XP_005563640.1//PREDICTED: peroxisome biogenesis factor 2 [Macaca fascicularis]","1//3;2//1"]
[112849,1877,17.17,17.06,-0.00927239268384427,0.814985600947471,"*",0.732334,"L3HYPDH","NA","GO:0016836//hydro-lyase activity;GO:0050346//trans-L-3-hydroxyproline dehydratase activity","GO:0008152//metabolic process","K18384//trans-L-3-hydroxyproline dehydratase [EC:4.2.1.77]","AAH12131.1//Chromosome 14 open reading frame 149 [Homo sapiens];NP_653182.1//trans-3-hydroxy-L-proline dehydratase isoform a [Homo sapiens];NP_001318093.1//trans-3-hydroxy-L-proline dehydratase isoform c [Homo sapiens];XP_004738925.1//PREDICTED: trans-3-hydroxy-L-proline dehydratase [Mustela putorius furo]","1//3"]
[55315,2277,10.93,10.86,-0.0092692978675432,0.989321271524896,"*",0.955258,"SLC29A3","GO:0005765//lysosomal membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005794//Golgi apparatus;GO:0031902//late endosome membrane;GO:0016021//integral component of membrane","GO:0005337//nucleoside transmembrane transporter activity","NA","K15014//solute carrier family 29 (equilibrative nucleoside transporter), member 1/2/3","NP_060814.4//equilibrative nucleoside transporter 3 isoform a [Homo sapiens]","1//3;5"]
[55766,3699,10.96,10.89,-0.00924384424361993,0.984178306993642,"*",0.949676,"H2AFJ","GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0000786//nucleosome","GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity","GO:0006342//chromatin silencing","K11251//histone H2A","NP_808760.1//histone H2A.J [Homo sapiens]","3//A2MP1"]
[10162,2297,36.03,35.8,-0.00923906427517164,0.955020963103742,"*",0.912274,"LPCAT3","GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0047144//2-acylglycerol-3-phosphate O-acyltransferase activity;GO:0047184//1-acylglycerophosphocholine O-acyltransferase activity;GO:0003841//1-acylglycerol-3-phosphate O-acyltransferase activity","GO:0097006//regulation of plasma lipoprotein particle levels;GO:0008654//phospholipid biosynthetic process;GO:0036152//phosphatidylethanolamine acyl-chain remodeling;GO:0036150//phosphatidylserine acyl-chain remodeling;GO:0036151//phosphatidylcholine acyl-chain remodeling","K13515//lysophospholipid acyltransferase 5 [EC:2.3.1.23 2.3.1.-]","NP_005759.4//lysophospholipid acyltransferase 5 [Homo sapiens]",5]
[6794,3286,15.9,15.8,-0.00910220710725244,0.976897042878522,"*",0.939898,"STK11","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005737//cytoplasm;GO:0036398//TCR signalosome","GO:0000287//magnesium ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0002039//p53 binding;GO:0030295//protein kinase activator activity;GO:0030275//LRR domain binding","GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0051896//regulation of protein kinase B signaling;GO:1904262//negative regulation of TORC1 signaling;GO:0042593//glucose homeostasis;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0006914//autophagy;GO:0048814//regulation of dendrite morphogenesis;GO:0008285//negative regulation of cell proliferation;GO:0071493//cellular response to UV-B;GO:0001558//regulation of cell growth;GO:0097484//dendrite extension;GO:0030154//cell differentiation;GO:0006468//protein phosphorylation;GO:0032147//activation of protein kinase activity;GO:0050772//positive regulation of axonogenesis;GO:0046777//protein autophosphorylation;GO:0007409//axonogenesis;GO:1901796//regulation of signal transduction by p53 class mediator;GO:0018107//peptidyl-threonine phosphorylation;GO:0030010//establishment of cell polarity;GO:0060070//canonical Wnt signaling pathway;GO:0018105//peptidyl-serine phosphorylation;GO:0060770//negative regulation of epithelial cell proliferation involved in prostate gland development;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:0007399//nervous system development;GO:0051055//negative regulation of lipid biosynthetic process;GO:0043276//anoikis;GO:0007283//spermatogenesis;GO:0007050//cell cycle arrest;GO:0001944//vasculature development;GO:0006974//cellular response to DNA damage stimulus;GO:0030308//negative regulation of cell growth;GO:1900182//positive regulation of protein localization to nucleus;GO:0010212//response to ionizing radiation;GO:0050852//T cell receptor signaling pathway;GO:0030111//regulation of Wnt signaling pathway;GO:0010508//positive regulation of autophagy;GO:0001894//tissue homeostasis;GO:0036399//TCR signalosome assembly;GO:0051645//Golgi localization;GO:0045059//positive thymic T cell selection;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway","K07298//serine/threonine-protein kinase 11 [EC:2.7.11.1]","NP_000446.1//serine/threonine-protein kinase STK11 [Homo sapiens]",4]
[92002,1311,21.15,21.02,-8.89499404513369E-3,0.944518748387097,"*",0.898162,"CCNQ","GO:0005634//nucleus;GO:0000307//cyclin-dependent protein kinase holoenzyme complex","GO:0030295//protein kinase activator activity;GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity","GO:1901409//positive regulation of phosphorylation of RNA polymerase II C-terminal domain;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0043410//positive regulation of MAPK cascade;GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity","K15188//cyclin T;K16667//receptor-type tyrosine-protein phosphatase gamma [EC:3.1.3.48];K21768//tubulin-specific chaperone E;K02333//DNA polymerase gamma 2","XP_011845984.1//PREDICTED: cyclin-related protein FAM58A-like [Mandrillus leucophaeus];EHH50685.1//hypothetical protein EGM_01551 [Macaca fascicularis]","4;2//1"]
[4218,2194,49.11,48.81,-0.00884007080162558,0.958657461352183,"*",0.916948,"RAB8A","NA","NA","NA","K07901//Ras-related protein Rab-8A","XP_012613861.1//ras-related protein Rab-8A [Microcebus murinus]",4]
[89953,2403,3.34,3.32,-0.00866486112712754,0.988672837969267,"*",0.95457,"KLC4","GO:0005874//microtubule;GO:0005737//cytoplasm;GO:0005871//kinesin complex","GO:0003777//microtubule motor activity","NA","K10407//kinesin light chain","NP_612352.1//kinesin light chain 4 isoform c [Homo sapiens];NP_001275964.1//kinesin light chain 4 isoform d [Homo sapiens];NP_958931.1//kinesin light chain 4 isoform b [Homo sapiens]","1//3;3//A2MP1;2//1"]
[9844,5539,1.67,1.66,-0.00866486112712721,0.535875501054111,"*",0.381896,"ELMO1","GO:0016020//membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0032045//guanyl-nucleotide exchange factor complex","GO:0005085//guanyl-nucleotide exchange factor activity;GO:0017124//SH3 domain binding","GO:0006911//phagocytosis, engulfment;GO:0016477//cell migration;GO:0030036//actin cytoskeleton organization;GO:0050690//regulation of defense response to virus by virus;GO:0006915//apoptotic process;GO:0016601//Rac protein signal transduction;GO:0065009//regulation of molecular function;GO:0048870//cell motility;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0006909//phagocytosis","K12366//engulfment and cell motility protein 1","XP_006201961.2//PREDICTED: engulfment and cell motility protein 1 isoform X1 [Vicugna pacos];EDL32677.1//engulfment and cell motility 1, ced-12 homolog (C. elegans), isoform CRA_a, partial [Mus musculus];XP_015092799.1//PREDICTED: engulfment and cell motility protein 1 isoform X3 [Vicugna pacos];XP_007979785.1//PREDICTED: engulfment and cell motility protein 1 isoform X2 [Chlorocebus sabaeus]","1//3;3//A2MP1;10//2;2//1"]
[29893,1456,18.64,18.53,-0.00853897862701444,1.01259247994825,"*",0.98001,"PSMC3IP","GO:0005654//nucleoplasm","GO:0003677//DNA binding;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity","GO:0007131//reciprocal meiotic recombination","K06695//26S proteasome regulatory subunit, ATPase 3, interacting protein","EAW60849.1//PSMC3 interacting protein, isoform CRA_c [Homo sapiens];EAW60846.1//PSMC3 interacting protein, isoform CRA_a [Homo sapiens]","6;1//3;3//A2MP1"]
[5202,668,44.41,44.15,-0.00847113343128436,0.994069370317563,"*",0.960216,"PFDN2","GO:0016272//prefoldin complex;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005737//cytoplasm","GO:0051082//unfolded protein binding;GO:0044183//protein binding involved in protein folding","GO:0006457//protein folding;GO:0051495//positive regulation of cytoskeleton organization","K09549//prefoldin subunit 2","XP_010614926.1//PREDICTED: prefoldin subunit 2 [Fukomys damarensis]","3//A2MP1"]
[10286,1310,12.05,11.98,-0.00840523832853827,1.00766456536371,"*",0.974736,"BCAS2","GO:0005654//nucleoplasm;GO:0000974//Prp19 complex;GO:0016607//nuclear speck;GO:0005813//centrosome;GO:0071013//catalytic step 2 spliceosome;GO:0005730//nucleolus;GO:0005681//spliceosomal complex;GO:0071011//precatalytic spliceosome;GO:0005662//DNA replication factor A complex","NA","GO:0006397//mRNA processing;GO:0000398//mRNA splicing, via spliceosome;GO:0008380//RNA splicing;GO:0000375//RNA splicing, via transesterification reactions","K12861//pre-mRNA-splicing factor SPF27","XP_008063201.1//pre-mRNA-splicing factor SPF27 isoform X1 [Carlito syrichta]","2//1"]
[64429,2207,26.01,25.86,-0.00834412413273694,0.899482800563116,"*",0.839964,"ZDHHC6","GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0016409//palmitoyltransferase activity;GO:0019706//protein-cysteine S-palmitoyltransferase activity","GO:0018345//protein palmitoylation","K20031//palmitoyltransferase ZDHHC6 [EC:2.3.1.225]","NP_001338015.1//palmitoyltransferase ZDHHC6 isoform 4 [Homo sapiens];NP_071939.1//palmitoyltransferase ZDHHC6 isoform 1 [Homo sapiens];NP_001290063.1//palmitoyltransferase ZDHHC6 isoform 2 [Homo sapiens];NP_001338014.1//palmitoyltransferase ZDHHC6 isoform 3 [Homo sapiens]","1//3;2//1"]
[54993,2245,8.88,8.83,-0.00814623870164012,0.468840506035198,"*",0.318538,"ZSCAN2","GO:0005634//nucleus","GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003700//DNA binding transcription factor activity","GO:0030154//cell differentiation;GO:0007275//multicellular organism development;GO:0006351//transcription, DNA-templated;GO:0007283//spermatogenesis","K09228//KRAB domain-containing zinc finger protein;K09230//SCAN domain-containing zinc finger protein","NP_060364.4//zinc finger and SCAN domain-containing protein 2 isoform 2 [Homo sapiens];NP_001007073.1//zinc finger and SCAN domain-containing protein 2 isoform 3 [Homo sapiens];XP_001086522.3//PREDICTED: zinc finger and SCAN domain-containing protein 2 [Macaca mulatta]","1//3;3//A2MP1;5"]
[120863,3216,1.78,1.77,-0.00812788088340034,1.02084400799845,"*",0.990744,"DEPDC4","GO:0005622//intracellular","NA","GO:0007165//signal transduction;GO:0035556//intracellular signal transduction","K01368//cathepsin S [EC:3.4.22.27];K08014//Rap guanine nucleotide exchange factor 3;K17985//activating molecule in BECN1-regulated autophagy protein 1","NP_001306240.1//DEP domain-containing protein 4 isoform 3 [Homo sapiens];NP_689530.1//DEP domain-containing protein 4 isoform 1 [Homo sapiens];NP_001306239.1//DEP domain-containing protein 4 isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[5931,2018,80.69,80.24,-0.00806828385598765,0.954341793654955,"*",0.911446,"RBBP7","GO:0016581//NuRD complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0035098//ESC/E(Z) complex","GO:0004407//histone deacetylase activity;GO:0003723//RNA binding","GO:0045892//negative regulation of transcription, DNA-templated;GO:0043687//post-translational protein modification;GO:0030308//negative regulation of cell growth;GO:0006355//regulation of transcription, DNA-templated;GO:0006260//DNA replication;GO:0006351//transcription, DNA-templated;GO:0048545//response to steroid hormone;GO:1901796//regulation of signal transduction by p53 class mediator;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0070370//cellular heat acclimation;GO:0016569//covalent chromatin modification;GO:0007275//multicellular organism development;GO:0045814//negative regulation of gene expression, epigenetic;GO:0034080//CENP-A containing nucleosome assembly","K11659//histone-binding protein RBBP7","NP_002884.1//histone-binding protein RBBP7 isoform 2 [Homo sapiens];NP_001185648.1//histone-binding protein RBBP7 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[84289,4383,10.8,10.74,-8.03731906541842E-3,0.621401018139263,"*",0.46537,"ING5","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0070776//MOZ/MORF histone acetyltransferase complex","GO:0046872//metal ion binding;GO:0003682//chromatin binding;GO:0035064//methylated histone binding","GO:0045926//negative regulation of growth;GO:0006260//DNA replication;GO:0016573//histone acetylation;GO:0006351//transcription, DNA-templated;GO:0006473//protein acetylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:2001235//positive regulation of apoptotic signaling pathway;GO:1901796//regulation of signal transduction by p53 class mediator;GO:0043065//positive regulation of apoptotic process;GO:0043966//histone H3 acetylation;GO:0008285//negative regulation of cell proliferation","K11345//inhibitor of growth protein 5","XP_002723766.2//PREDICTED: inhibitor of growth protein 5 isoform X3 [Oryctolagus cuniculus];NP_001317090.1//inhibitor of growth protein 5 isoform 2 [Homo sapiens]","1//3;5"]
[2665,2399,116.07,115.43,-0.00797690866930126,0.631509509568451,"*",0.51026,"GDI2","GO:0034774//secretory granule lumen;GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005925//focal adhesion;GO:0031982//vesicle;GO:0005737//cytoplasm;GO:0035578//azurophil granule lumen;GO:0005829//cytosol;GO:0005576//extracellular region","GO:0031267//small GTPase binding;GO:0003723//RNA binding;GO:0005093//Rab GDP-dissociation inhibitor activity;GO:0005096//GTPase activator activity","GO:0007165//signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0043312//neutrophil degranulation;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0061024//membrane organization","K17255//Rab GDP dissociation inhibitor","NP_001108628.1//rab GDP dissociation inhibitor beta isoform 2 [Homo sapiens];BAE25494.1//unnamed protein product, partial [Mus musculus]","1//3;3//A2MP1"]
[6836,2926,139.99,139.22,-0.00795729377670972,0.835889348314607,"*",0.759124,"SURF4","GO:0030133//transport vesicle;GO:0016021//integral component of membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0035577//azurophil granule membrane;GO:0000139//Golgi membrane","NA","GO:0043312//neutrophil degranulation;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0010638//positive regulation of organelle organization;GO:0007030//Golgi organization","K20369//ER-derived vesicles protein","NP_001267718.1//surfeit locus protein 4 isoform 3 [Homo sapiens];NP_001267717.1//surfeit locus protein 4 isoform 2 [Homo sapiens];XP_008068997.2//surfeit locus protein 4 isoform X1 [Carlito syrichta];NP_149351.1//surfeit locus protein 4 isoform 1 [Homo sapiens];XP_016817488.1//PREDICTED: surfeit locus protein 4 isoform X1 [Pan troglodytes];XP_011517247.1//PREDICTED: surfeit locus protein 4 isoform X2 [Homo sapiens];CAF99172.1//unnamed protein product [Tetraodon nigroviridis]","1//3;3//A2MP1"]
[84270,943,52.46,52.18,-0.00772086344753222,0.966764287970759,"*",0.927244,"CARD19","GO:0005634//nucleus;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0031966//mitochondrial membrane;GO:0005789//endoplasmic reticulum membrane","GO:0050700//CARD domain binding","GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling","K11647//SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:3.6.4.-];K06836//disintegrin and metalloproteinase domain-containing protein 15 [EC:3.4.24.-];K07604//type I keratin, acidic","NP_115686.3//caspase recruitment domain-containing protein 19 isoform 1 [Homo sapiens];NP_001304940.1//caspase recruitment domain-containing protein 19 isoform 3 [Homo sapiens];NP_001304939.1//caspase recruitment domain-containing protein 19 isoform 2 [Homo sapiens]","4;1//3"]
[6623,861,5.66,5.63,-0.0076671307516528,0.973033145462836,"*",0.935084,"SNCG","GO:0070062//extracellular exosome;GO:0030424//axon;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0043025//neuronal cell body","NA","GO:0009306//protein secretion;GO:0007268//chemical synaptic transmission;GO:0008344//adult locomotory behavior;GO:0050808//synapse organization;GO:0046928//regulation of neurotransmitter secretion;GO:0014059//regulation of dopamine secretion","K04528//alpha-synuclein","NP_001317049.1//gamma-synuclein isoform 2 [Homo sapiens];XP_007960887.1//PREDICTED: gamma-synuclein isoform X1 [Chlorocebus sabaeus]","1//3;2//1"]
[84752,2722,11.4,11.34,-0.00761318410987521,0.997859158903932,"*",0.964314,"B3GNT9","NA","NA","NA","K18705//beta-1,3-N-acetylglucosaminyltransferase 9 [EC:2.4.1.-]","XP_011756226.1//PREDICTED: UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 isoform X1 [Macaca nemestrina]","2//1"]
[10965,1794,28.64,28.49,-0.00757587094040535,0.975373583599089,"*",0.938188,"ACOT2","NA","GO:0016790//thiolester hydrolase activity","GO:0006637//acyl-CoA metabolic process","K01068//acyl-coenzyme A thioesterase 1/2/4 [EC:3.1.2.2]","XP_014999556.1//PREDICTED: acyl-coenzyme A thioesterase 2, mitochondrial isoform X1 [Macaca mulatta]",5]
[118424,2280,23.3,23.18,-0.00744938853517087,0.960082753369096,"*",0.918732,"UBE2J2","GO:0005783//endoplasmic reticulum;GO:0000151//ubiquitin ligase complex;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0061630//ubiquitin protein ligase activity;GO:0005524//ATP binding;GO:0031625//ubiquitin protein ligase binding;GO:0061631//ubiquitin conjugating enzyme activity","GO:0006986//response to unfolded protein;GO:1903955//positive regulation of protein targeting to mitochondrion;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0016567//protein ubiquitination;GO:0000209//protein polyubiquitination","K04554//ubiquitin-conjugating enzyme E2 J2 [EC:2.3.2.23]","NP_477515.2//ubiquitin-conjugating enzyme E2 J2 isoform 2 [Homo sapiens];XP_008959957.1//PREDICTED: ubiquitin-conjugating enzyme E2 J2 isoform X1 [Pan paniscus];NP_919296.1//ubiquitin-conjugating enzyme E2 J2 isoform 1 [Homo sapiens]","1//3;2//1"]
[79139,3332,29.43,29.28,-0.00737198865635244,0.978418404108699,"*",0.942158,"DERL1","GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0005770//late endosome;GO:0048500//signal recognition particle;GO:0036502//Derlin-1-VIMP complex;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0036513//Derlin-1 retrotranslocation complex;GO:0005789//endoplasmic reticulum membrane;GO:0005769//early endosome;GO:0005785//signal recognition particle receptor complex","GO:0002020//protease binding;GO:0004872//receptor activity;GO:0031625//ubiquitin protein ligase binding;GO:0042288//MHC class I protein binding;GO:0051117//ATPase binding;GO:1990381//ubiquitin-specific protease binding","GO:0030970//retrograde protein transport, ER to cytosol;GO:0006986//response to unfolded protein;GO:0034620//cellular response to unfolded protein;GO:0016567//protein ubiquitination;GO:0051260//protein homooligomerization;GO:0032092//positive regulation of protein binding;GO:0036503//ERAD pathway;GO:0015031//protein transport;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0031648//protein destabilization;GO:0045184//establishment of protein localization;GO:0006457//protein folding;GO:0055085//transmembrane transport;GO:0071712//ER-associated misfolded protein catabolic process;GO:0031398//positive regulation of protein ubiquitination;GO:0030433//ubiquitin-dependent ERAD pathway;GO:0016032//viral process","K11519//Derlin-1","XP_007126133.1//PREDICTED: derlin-1 isoform X1 [Physeter catodon];NP_001128143.1//derlin-1 isoform b [Homo sapiens];NP_077271.1//derlin-1 isoform a [Homo sapiens]","1//3;2//1;5"]
[23654,6356,29.72,29.57,-0.00729987241827203,0.966057887989556,"*",0.926506,"PLXNB2","GO:0070062//extracellular exosome;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane","GO:0017154//semaphorin receptor activity","GO:0007162//negative regulation of cell adhesion;GO:0010976//positive regulation of neuron projection development;GO:0050772//positive regulation of axonogenesis;GO:0008360//regulation of cell shape;GO:0007420//brain development;GO:0001932//regulation of protein phosphorylation;GO:0007405//neuroblast proliferation;GO:0043087//regulation of GTPase activity;GO:2001222//regulation of neuron migration;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0001843//neural tube closure;GO:0071526//semaphorin-plexin signaling pathway","K06821//plexin B","XP_011528984.1//PREDICTED: plexin-B2 isoform X1 [Homo sapiens]","3//A2MP1"]
[10712,3066,45.58,45.35,-0.00729837384941226,0.911700549019608,"*",0.855768,"FAM189B","GO:0016021//integral component of membrane","GO:0050699//WW domain binding","NA","K01201//glucosylceramidase [EC:3.2.1.45];K07412//cytochrome P450 family 2 subfamily B [EC:1.14.14.1]","NP_937995.1//protein FAM189B isoform b [Homo sapiens];XP_008968457.1//PREDICTED: LOW QUALITY PROTEIN: protein FAM189B [Pan paniscus]","1//3;2//1"]
[55742,8719,8.09,8.05,-0.00715091942799804,0.991259968103728,"*",0.957192,"PARVA","GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0030018//Z disc;GO:0005925//focal adhesion;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0030027//lamellipodium;GO:0005886//plasma membrane","GO:0003779//actin binding;GO:0045296//cadherin binding","GO:0003148//outflow tract septum morphogenesis;GO:0031532//actin cytoskeleton reorganization;GO:0034446//substrate adhesion-dependent cell spreading;GO:0070252//actin-mediated cell contraction;GO:0071670//smooth muscle cell chemotaxis;GO:0008360//regulation of cell shape;GO:0007155//cell adhesion;GO:0060271//cilium assembly;GO:0007163//establishment or maintenance of cell polarity;GO:0034113//heterotypic cell-cell adhesion;GO:0002040//sprouting angiogenesis","K06275//parvin","XP_002755106.3//PREDICTED: alpha-parvin [Callithrix jacchus]",4]
[54808,4983,6.11,6.08,-0.00710105637514406,0.97295008949391,"*",0.935126,"DYM","GO:0016020//membrane;GO:0005794//Golgi apparatus;GO:0005737//cytoplasm","GO:0019899//enzyme binding","GO:0060348//bone development;GO:0007030//Golgi organization","K02927//large subunit ribosomal protein L40e;K15696//RING finger protein 113B;K17985//activating molecule in BECN1-regulated autophagy protein 1;K01064//wingless-type MMTV integration site family, member 9","NP_001340141.1//dymeclin isoform 4 [Homo sapiens];NP_001340139.1//dymeclin isoform 2 [Homo sapiens];NP_001340145.1//dymeclin isoform 8 [Homo sapiens];NP_001340142.1//dymeclin isoform 5 [Homo sapiens];NP_001340143.1//dymeclin isoform 6 [Homo sapiens];NP_001340140.1//dymeclin isoform 3 [Homo sapiens];NP_060123.3//dymeclin isoform 1 [Homo sapiens];NP_001340144.1//dymeclin isoform 7 [Homo sapiens]","4;1//3"]
[127281,2749,18.61,18.52,-0.0069939567989151,0.940998688295417,"*",0.893342,"FAM213B","GO:0070062//extracellular exosome;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0043209//myelin sheath;GO:0005737//cytoplasm","GO:0016209//antioxidant activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0047017//prostaglandin-F synthase activity","GO:0001516//prostaglandin biosynthetic process;GO:0055114//oxidation-reduction process","K15717//prostamide/prostaglandin F2alpha synthase [EC:1.11.1.20]","NP_689584.2//prostamide/prostaglandin F synthase isoform b [Homo sapiens];NP_001182665.1//prostamide/prostaglandin F synthase isoform a [Homo sapiens];XP_009445112.1//PREDICTED: prostamide/prostaglandin F synthase isoform X1 [Pan troglodytes]","1//3;3//A2MP1"]
[5906,5036,4.18,4.16,-0.00691941393979047,0.956195502913638,"*",0.914234,"RAP1A","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005770//late endosome;GO:0043209//myelin sheath;GO:0030054//cell junction;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0043005//neuron projection;GO:0045335//phagocytic vesicle;GO:0005829//cytosol;GO:0035579//specific granule membrane;GO:0005886//plasma membrane;GO:0005769//early endosome;GO:0032045//guanyl-nucleotide exchange factor complex","GO:0008565//protein transporter activity;GO:0017034//Rap guanyl-nucleotide exchange factor activity;GO:0017016//Ras GTPase binding;GO:0005525//GTP binding;GO:0032403//protein complex binding;GO:0003924//GTPase activity","GO:0097421//liver regeneration;GO:0035690//cellular response to drug;GO:2000301//negative regulation of synaptic vesicle exocytosis;GO:0043547//positive regulation of GTPase activity;GO:1905451//positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis;GO:1990090//cellular response to nerve growth factor stimulus;GO:0071320//cellular response to cAMP;GO:0050796//regulation of insulin secretion;GO:0046326//positive regulation of glucose import;GO:0071407//cellular response to organic cyclic compound;GO:0007264//small GTPase mediated signal transduction;GO:0043312//neutrophil degranulation;GO:1901888//regulation of cell junction assembly;GO:0045860//positive regulation of protein kinase activity;GO:0015031//protein transport;GO:0000186//activation of MAPKK activity;GO:0007165//signal transduction;GO:0032966//negative regulation of collagen biosynthetic process;GO:2001214//positive regulation of vasculogenesis;GO:0010976//positive regulation of neuron projection development;GO:0071333//cellular response to glucose stimulus;GO:0097327//response to antineoplastic agent;GO:0038180//nerve growth factor signaling pathway;GO:0009743//response to carbohydrate;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0061028//establishment of endothelial barrier;GO:0032486//Rap protein signal transduction","K04353//Ras-related protein Rap-1A;K06235//zinc finger protein ZIC 2;K09349//homeobox protein Nkx-5","XP_004279208.1//PREDICTED: ras-related protein R-Ras2 isoform X1 [Orcinus orca];NP_002875.1//ras-related protein Rap-1A precursor [Homo sapiens];OXB61440.1//hypothetical protein ASZ78_015546 [Callipepla squamata]","1//3;3//A2MP1;2//1"]
[81932,1551,19.12,19.03,-0.0068069617067266,0.896015091958652,"*",0.83566,"HDHD3","GO:0005739//mitochondrion","GO:0016787//hydrolase activity","GO:0008152//metabolic process","K01698//porphobilinogen synthase [EC:4.2.1.24]","NP_112496.1//haloacid dehalogenase-like hydrolase domain-containing protein 3 [Homo sapiens]","1//3;3//A2MP1"]
[4724,675,34.02,33.86,-6.80116776774341E-3,1.01401287374749,"*",0.981956,"NDUFS4","GO:0045271//respiratory chain complex I;GO:0005747//mitochondrial respiratory chain complex I;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0016651//oxidoreductase activity, acting on NAD(P)H;GO:0008137//NADH dehydrogenase (ubiquinone) activity","GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0051591//response to cAMP;GO:0048146//positive regulation of fibroblast proliferation;GO:0072593//reactive oxygen species metabolic process;GO:0007420//brain development;GO:0019933//cAMP-mediated signaling;GO:0001932//regulation of protein phosphorylation;GO:0022900//electron transport chain;GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0045333//cellular respiration","K03937//NADH dehydrogenase (ubiquinone) Fe-S protein 4","NP_002486.1//NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial isoform 1 precursor [Homo sapiens];NP_001304980.1//NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial isoform 2 precursor [Homo sapiens]","1//3;3//A2MP1"]
[23135,6652,6.41,6.38,-6.76793285387166E-3,0.967525114779772,"*",0.928216,"KDM6B","GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0046872//metal ion binding;GO:0003682//chromatin binding;GO:0043565//sequence-specific DNA binding;GO:0071558//histone demethylase activity (H3-K27 specific);GO:0032452//histone demethylase activity;GO:0051213//dioxygenase activity;GO:0008013//beta-catenin binding","GO:0045165//cell fate commitment;GO:0055007//cardiac muscle cell differentiation;GO:0006338//chromatin remodeling;GO:0014823//response to activity;GO:0021766//hippocampus development;GO:0071557//histone H3-K27 demethylation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045446//endothelial cell differentiation;GO:0048333//mesodermal cell differentiation;GO:0060992//response to fungicide;GO:0070301//cellular response to hydrogen peroxide;GO:0002437//inflammatory response to antigenic stimulus","K11448//lysine-specific demethylase 6B [EC:1.14.11.-]","NP_001073893.1//lysine-specific demethylase 6B isoform 1 [Homo sapiens];NP_001335645.1//lysine-specific demethylase 6B isoform 2 [Homo sapiens]","1//3;2//1"]
[79134,5938,15.04,14.97,-0.00673034561922056,0.987033449640054,"*",0.95274,"TMEM185B","GO:0016021//integral component of membrane","NA","NA","K11447//histone demethylase [EC:1.14.11.-];K17776//metaxin;K01064//wingless-type MMTV integration site family, member 9","NP_077026.2//transmembrane protein 185B [Homo sapiens]","2//1"]
[23564,1409,15.09,15.02,-0.00670799301241158,0.929885270304316,"*",0.878018,"DDAH2","GO:0070062//extracellular exosome;GO:0005815//microtubule organizing center;GO:0005829//cytosol;GO:0005739//mitochondrion","GO:0016403//dimethylargininase activity;GO:0016597//amino acid binding;GO:0003824//catalytic activity","GO:0050999//regulation of nitric-oxide synthase activity;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0007263//nitric oxide mediated signal transduction;GO:0043066//negative regulation of apoptotic process;GO:0006809//nitric oxide biosynthetic process;GO:0000052//citrulline metabolic process;GO:0006527//arginine catabolic process","K01482//dimethylargininase [EC:3.5.3.18]","XP_012596449.1//N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 isoform X2 [Microcebus murinus]","1//3;2//1"]
[55692,1716,21.83,21.73,-0.00662395580950797,0.780312383651381,"*",0.686034,"LUC7L","GO:0005685//U1 snRNP;GO:0071004//U2-type prespliceosome","GO:0050733//RS domain binding;GO:0003729//mRNA binding;GO:0042802//identical protein binding","GO:0006376//mRNA splice site selection;GO:0045843//negative regulation of striated muscle tissue development","K13212//RNA-binding protein Luc7-like 2","XP_017366351.1//PREDICTED: putative RNA-binding protein Luc7-like 1 isoform X1 [Cebus capucinus imitator];NP_958815.1//putative RNA-binding protein Luc7-like 1 isoform b [Homo sapiens]","4;1//3;2//1"]
[25963,3096,8.79,8.75,-0.00658014842371274,0.920734646628541,"*",0.866784,"TMEM87A","GO:0032580//Golgi cisterna membrane;GO:0005829//cytosol;GO:0016021//integral component of membrane","NA","GO:0042147//retrograde transport, endosome to Golgi","K02927//large subunit ribosomal protein L40e;K15696//RING finger protein 113B;K17985//activating molecule in BECN1-regulated autophagy protein 1","BAC11598.1//unnamed protein product [Homo sapiens];NP_001103973.1//transmembrane protein 87A isoform 2 precursor [Homo sapiens];NP_001273416.1//transmembrane protein 87A isoform 3 [Homo sapiens]","4;1//3;2//1"]
[9403,1789,48.46,48.24,-0.0065644975512616,1.00005434978624,"*",0.966498,"SELENOF","GO:0070062//extracellular exosome;GO:0005788//endoplasmic reticulum lumen","NA","GO:0051084//'de novo' posttranslational protein folding","NA","XP_005885381.2//PREDICTED: 15 kDa selenoprotein [Myotis brandtii];NP_976086.1//selenoprotein F isoform 2 precursor [Homo sapiens]","4;2//1"]
[199870,3425,2.23,2.22,-0.00648403357019863,0.970254158399061,"*",0.931806,"FAM76A","GO:0005654//nucleoplasm","NA","NA","K20394//sestrin 2;K01064//wingless-type MMTV integration site family, member 9","NP_001137386.1//protein FAM76A isoform 4 [Homo sapiens];NP_001137385.1//protein FAM76A isoform 2 [Homo sapiens];NP_689873.1//protein FAM76A isoform 3 [Homo sapiens];NP_001137387.1//protein FAM76A isoform 5 [Homo sapiens];NP_001137384.1//protein FAM76A isoform 1 [Homo sapiens]","1//3;2//1"]
[726,4393,9.03,8.99,-0.00640487196641073,1.00718717167271,"*",0.974022,"CAPN5","NA","NA","NA","K08574//calpain-5 [EC:3.4.22.-]","BAD92324.1//Hypothetical protein FLJ46245 variant, partial [Homo sapiens]",4]
[286053,1225,13.8,13.74,-0.00628626284743141,0.97467293665777,"*",0.93727,"NSMCE2","GO:0030915//Smc5-Smc6 complex;GO:0016605//PML body;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000781//chromosome, telomeric region;GO:0016604//nuclear body","GO:0008270//zinc ion binding;GO:0004842//ubiquitin-protein transferase activity;GO:0019789//SUMO transferase activity;GO:0016874//ligase activity","GO:0000722//telomere maintenance via recombination;GO:0045842//positive regulation of mitotic metaphase/anaphase transition;GO:0034184//positive regulation of maintenance of mitotic sister chromatid cohesion;GO:0090398//cellular senescence;GO:0051301//cell division;GO:0000724//double-strand break repair via homologous recombination;GO:0007049//cell cycle","NA","NP_001336416.1//E3 SUMO-protein ligase NSE2 isoform 2 [Homo sapiens];XP_001152705.2//PREDICTED: E3 SUMO-protein ligase NSE2 isoform X2 [Pan troglodytes]","1//3;3//A2MP1"]
[54902,3523,16.57,16.5,-6.10757808827379E-3,1.0005310761658,"*",0.967084,"TTC19","GO:0005743//mitochondrial inner membrane;GO:0005813//centrosome;GO:0070469//respiratory chain;GO:0005739//mitochondrion;GO:0030496//midbody","NA","GO:0034551//mitochondrial respiratory chain complex III assembly;GO:0000910//cytokinesis;GO:0055114//oxidation-reduction process","K18169//tetratricopeptide repeat protein 19, mitochondrial","XP_004042270.2//PREDICTED: tetratricopeptide repeat protein 19, mitochondrial isoform X1 [Gorilla gorilla gorilla];AAI05129.1//Tetratricopeptide repeat domain 19 [Homo sapiens]","1//3;3//A2MP1"]
[112611,3904,2.38,2.37,-0.00607451440968423,0.950210588096177,"*",0.905478,"RWDD2A","NA","NA","NA","K15322//tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9];K02927//large subunit ribosomal protein L40e;K17985//activating molecule in BECN1-regulated autophagy protein 1;K12025//tripartite motif-containing protein 52","XP_015354503.1//PREDICTED: RWD domain-containing protein 2A isoform X2 [Marmota marmota marmota];NP_219479.2//RWD domain-containing protein 2A isoform a [Homo sapiens];XP_018885074.1//PREDICTED: RWD domain-containing protein 2A isoform X2 [Gorilla gorilla gorilla]","4;1//3"]
[10179,3749,4.85,4.83,-0.00596155823871668,1.01202425955878,"*",0.97927,"RBM7","GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0003723//RNA binding;GO:0003727//single-stranded RNA binding","GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0051321//meiotic cell cycle","K13188//RNA-binding protein 7","NP_057174.1//RNA-binding protein 7 isoform b [Homo sapiens];NP_001272974.1//RNA-binding protein 7 isoform a [Homo sapiens]","1//3;3//A2MP1"]
[8846,2585,7.72,7.69,-0.00561724930625392,1.01385220095694,"*",0.98161,"ALKBH1","GO:0005719//nuclear euchromatin;GO:0005739//mitochondrion","GO:0003906//DNA-(apurinic or apyrimidinic site) lyase activity;GO:0000049//tRNA binding;GO:0070579//methylcytosine dioxygenase activity;GO:0043734//DNA-N1-methyladenine dioxygenase activity;GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;GO:0140078//class I DNA-(apurinic or apyrimidinic site) lyase activity;GO:0042056//chemoattractant activity;GO:0140080//class III/IV DNA-(apurinic or apyrimidinic site) lyase activity;GO:0016491//oxidoreductase activity;GO:1990984//tRNA demethylase activity;GO:0103053//1-ethyladenine demethylase activity;GO:0008198//ferrous iron binding","GO:1990983//tRNA demethylation;GO:0070989//oxidative demethylation;GO:0006448//regulation of translational elongation;GO:0080111//DNA demethylation;GO:0001890//placenta development;GO:0002101//tRNA wobble cytosine modification;GO:0006307//DNA dealkylation involved in DNA repair;GO:0031175//neuron projection development;GO:0006281//DNA repair;GO:0043524//negative regulation of neuron apoptotic process;GO:0035552//oxidative single-stranded DNA demethylation;GO:0001701//in utero embryonic development;GO:0042245//RNA repair;GO:0070129//regulation of mitochondrial translation;GO:0006446//regulation of translational initiation;GO:0001764//neuron migration;GO:0048589//developmental growth","K10765//alkylated DNA repair protein alkB homolog 1 [EC:1.14.11.- 4.2.99.18]","NP_006011.2//nucleic acid dioxygenase ALKBH1 [Homo sapiens]","2//1"]
[23413,4928,27.34,27.24,-0.00528653959398898,0.973133541967832,"*",0.935546,"NCS1","GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular exosome;GO:0030425//dendrite;GO:0030424//axon;GO:0031410//cytoplasmic vesicle;GO:0030054//cell junction;GO:0005737//cytoplasm;GO:0014069//postsynaptic density;GO:0048471//perinuclear region of cytoplasm;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0031045//dense core granule;GO:0005886//plasma membrane;GO:0045211//postsynaptic membrane","GO:0000287//magnesium ion binding;GO:0005245//voltage-gated calcium channel activity;GO:0005509//calcium ion binding;GO:0008427//calcium-dependent protein kinase inhibitor activity;GO:0019901//protein kinase binding","GO:0050806//positive regulation of synaptic transmission;GO:0045921//positive regulation of exocytosis;GO:0048015//phosphatidylinositol-mediated signaling;GO:0010975//regulation of neuron projection development","K19932//neuronal calcium sensor 1","EHA99921.1//Neuronal calcium sensor 1 [Heterocephalus glaber];NP_062655.1//neuronal calcium sensor 1 [Mus musculus]","1//3;3//A2MP1"]
[5316,5046,2.78,2.77,-0.00519890667431923,0.91480718667111,"*",0.859314,"PKNOX1","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005667//transcription factor complex;GO:0005737//cytoplasm","GO:0003677//DNA binding;GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0046982//protein heterodimerization activity;GO:0003700//DNA binding transcription factor activity;GO:0003705//transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding","GO:0043010//camera-type eye development;GO:0001525//angiogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0030217//T cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0030218//erythrocyte differentiation","K16672//homeobox protein homothorax;K16670//homeobox protein Meis2;K15613//homeobox protein Meis1;K16671//homeobox protein Meis3","NP_004562.2//homeobox protein PKNOX1 isoform 1 [Homo sapiens];XP_012300320.1//homeobox protein PKNOX1 isoform X3 [Aotus nancymaae];NP_001307623.1//homeobox protein PKNOX1 isoform 3 [Homo sapiens]","4;1//3"]
[79087,2387,11.19,11.15,-0.00516632616872677,1.01968655308164,"*",0.98911,"ALG12","GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane","GO:0000009//alpha-1,6-mannosyltransferase activity;GO:0016757//transferase activity, transferring glycosyl groups;GO:0000030//mannosyltransferase activity;GO:0052917//dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity","GO:0006457//protein folding;GO:0006487//protein N-linked glycosylation;GO:0006488//dolichol-linked oligosaccharide biosynthetic process","K03847//alpha-1,6-mannosyltransferase [EC:2.4.1.260]","NP_077010.1//dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase [Homo sapiens]","3//A2MP1"]
[10013,4089,14.16,14.11,-5.10327748573337E-3,1.00387756928257,"*",0.97057,"HDAC6","GO:0030425//dendrite;GO:0031252//cell leading edge;GO:0030424//axon;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005881//cytoplasmic microtubule;GO:0016235//aggresome;GO:0043204//perikaryon;GO:0005901//caveola;GO:0043234//protein complex;GO:0005829//cytosol","GO:0032041//NAD-dependent histone deacetylase activity (H3-K14 specific);GO:0042903//tubulin deacetylase activity;GO:0008017//microtubule binding;GO:0003779//actin binding;GO:0043130//ubiquitin binding;GO:0048487//beta-tubulin binding;GO:0043014//alpha-tubulin binding;GO:0008270//zinc ion binding;GO:0008013//beta-catenin binding","GO:0006355//regulation of transcription, DNA-templated;GO:0060997//dendritic spine morphogenesis;GO:0048668//collateral sprouting;GO:0007026//negative regulation of microtubule depolymerization;GO:0006914//autophagy;GO:0071218//cellular response to misfolded protein;GO:0070201//regulation of establishment of protein localization;GO:0000209//protein polyubiquitination;GO:0043241//protein complex disassembly;GO:0070301//cellular response to hydrogen peroxide;GO:0098779//positive regulation of mitophagy in response to mitochondrial depolarization;GO:0045598//regulation of fat cell differentiation;GO:0070846//Hsp90 deacetylation;GO:0051646//mitochondrion localization;GO:0006351//transcription, DNA-templated;GO:0070842//aggresome assembly;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway","K11407//histone deacetylase 6 [EC:3.5.1.98]","EAW50744.1//histone deacetylase 6, isoform CRA_a [Homo sapiens];EHH30703.1//Histone deacetylase 6 [Macaca mulatta];XP_016799016.1//PREDICTED: histone deacetylase 6 [Pan troglodytes]","1//3;3//A2MP1"]
[84060,4703,2.85,2.84,-0.00507098954742214,1.01689338947368,"*",0.985764,"RBM48","GO:0005654//nucleoplasm","GO:0003723//RNA binding;GO:0003676//nucleic acid binding","NA","K17985//activating molecule in BECN1-regulated autophagy protein 1;K15696//RING finger protein 113B","AAH33561.1//C7orf64 protein, partial [Homo sapiens]","3//A2MP1"]
[9831,3979,5.79,5.77,-0.00499202934375419,0.911156533600267,"*",0.854744,"ZNF623","NA","NA","NA","K09228//KRAB domain-containing zinc finger protein","XP_005215331.1//PREDICTED: zinc finger protein 623 [Bos taurus]","1//3;3//A2MP1;2//1"]
[7374,2081,41.46,41.32,-0.00487986224435524,1.00073337205947,"*",0.998666,"UNG","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion","GO:0003684//damaged DNA binding;GO:0004844//uracil DNA N-glycosylase activity;GO:0043024//ribosomal small subunit binding","GO:0006281//DNA repair;GO:0006284//base-excision repair;GO:0016446//somatic hypermutation of immunoglobulin genes;GO:0016447//somatic recombination of immunoglobulin gene segments;GO:0043066//negative regulation of apoptotic process;GO:0016032//viral process;GO:0045830//positive regulation of isotype switching;GO:0045008//depyrimidination;GO:0097510//base-excision repair, AP site formation via deaminated base removal","K03648//uracil-DNA glycosylase [EC:3.2.2.27]","XP_008002807.1//PREDICTED: uracil-DNA glycosylase isoform X1 [Chlorocebus sabaeus];NP_003353.1//uracil-DNA glycosylase isoform UNG1 precursor [Homo sapiens]","3//A2MP1;2//1"]
[221079,7277,2.98,2.97,-0.00484939966139585,1.01545152690395,"*",0.984112,"ARL5B","GO:0005622//intracellular","GO:0005525//GTP binding","GO:1903292//protein localization to Golgi membrane;GO:0007264//small GTPase mediated signal transduction","K07950//ADP-ribosylation factor-like protein 5B","NP_083742.2//ADP-ribosylation factor-like protein 5B [Mus musculus]",4]
[51005,1808,15.02,14.97,-0.00481059145585491,0.737754759221609,"*",0.636056,"AMDHD2","GO:0005634//nucleus;GO:0005829//cytosol","GO:0046872//metal ion binding;GO:0008448//N-acetylglucosamine-6-phosphate deacetylase activity","GO:0006044//N-acetylglucosamine metabolic process;GO:0006046//N-acetylglucosamine catabolic process;GO:0006048//UDP-N-acetylglucosamine biosynthetic process;GO:0005975//carbohydrate metabolic process;GO:0019262//N-acetylneuraminate catabolic process","K01443//N-acetylglucosamine-6-phosphate deacetylase [EC:3.5.1.25]","NP_001317378.1//N-acetylglucosamine-6-phosphate deacetylase isoform 3 [Homo sapiens];NP_057028.2//N-acetylglucosamine-6-phosphate deacetylase isoform 1 [Homo sapiens];NP_001139287.1//N-acetylglucosamine-6-phosphate deacetylase isoform 2 [Homo sapiens]","1//3;3//A2MP1"]
[10797,2208,69.47,69.24,-0.00478437262646308,1.00375638541734,"*",0.97039,"MTHFD2","GO:0005759//mitochondrial matrix;GO:0005615//extracellular space;GO:0005739//mitochondrion","GO:0004488//methylenetetrahydrofolate dehydrogenase (NADP+) activity;GO:0000287//magnesium ion binding;GO:0042301//phosphate ion binding;GO:0004477//methenyltetrahydrofolate cyclohydrolase activity;GO:0004487//methylenetetrahydrofolate dehydrogenase (NAD+) activity","GO:0046653//tetrahydrofolate metabolic process;GO:0006730//one-carbon metabolic process;GO:0046655//folic acid metabolic process","K13403//methylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.15 3.5.4.9]","XP_007968376.1//PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Chlorocebus sabaeus]","3//A2MP1"]
[7869,2687,3.17,3.16,-0.0045582819623043,0.850285239328537,"*",0.776882,"SEMA3B","GO:0070062//extracellular exosome;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum","GO:0038191//neuropilin binding","GO:0007267//cell-cell signaling;GO:0050919//negative chemotaxis;GO:0007411//axon guidance","K06840//semaphorin 3","NP_004627.1//semaphorin-3B isoform 1 precursor [Homo sapiens];NP_001276990.1//semaphorin-3B isoform 3 precursor [Homo sapiens];NP_001005914.1//semaphorin-3B isoform 2 precursor [Homo sapiens];AAH44602.1//SEMA3B protein, partial [Homo sapiens]","1//3;3//A2MP1;2//1"]
[347240,6286,3.44,3.43,-0.00419998852928546,1.0154201248062,"*",0.984018,"KIF24","GO:0005814//centriole;GO:0005874//microtubule;GO:0043234//protein complex;GO:0005829//cytosol;GO:0005871//kinesin complex","GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0003777//microtubule motor activity;GO:0008017//microtubule binding;GO:0016887//ATPase activity","GO:0007018//microtubule-based movement;GO:0060271//cilium assembly;GO:0097711//ciliary basal body-plasma membrane docking;GO:0007019//microtubule depolymerization","K10393//kinesin family member 2/24","XP_011516163.1//PREDICTED: kinesin-like protein KIF24 isoform X1 [Homo sapiens]","3//A2MP1"]
[8504,2774,3.54,3.53,-4.08117681181703E-3,1.01884375025826,"*",0.987846,"PEX3","GO:0016020//membrane;GO:0005654//nucleoplasm;GO:0005783//endoplasmic reticulum;GO:0032994//protein-lipid complex;GO:0005777//peroxisome;GO:0005779//integral component of peroxisomal membrane;GO:0005829//cytosol;GO:0043234//protein complex;GO:0005778//peroxisomal membrane","GO:0008289//lipid binding;GO:0046983//protein dimerization activity","GO:0007031//peroxisome organization;GO:0055085//transmembrane transport;GO:0016557//peroxisome membrane biogenesis;GO:0045046//protein import into peroxisome membrane","K13336//peroxin-3","NP_003621.1//peroxisomal biogenesis factor 3 [Homo sapiens]","2//1"]
[1522,1517,81.52,81.29,-0.00407616338236538,1.01623612349826,"*",0.984936,"CTSZ","GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0031410//cytoplasmic vesicle;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0000139//Golgi membrane;GO:0030134//COPII-coated ER to Golgi transport vesicle;GO:0030426//growth cone;GO:1904813//ficolin-1-rich granule lumen;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0070062//extracellular exosome;GO:0043231//intracellular membrane-bounded organelle;GO:0099738//cell cortex region;GO:0035580//specific granule lumen;GO:0005764//lysosome;GO:0009986//cell surface","GO:0004180//carboxypeptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0004197//cysteine-type endopeptidase activity","GO:0043525//positive regulation of neuron apoptotic process;GO:0060441//epithelial tube branching involved in lung morphogenesis;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0010757//negative regulation of plasminogen activation;GO:0048208//COPII vesicle coating;GO:2000179//positive regulation of neural precursor cell proliferation;GO:0006508//proteolysis;GO:0010977//negative regulation of neuron projection development;GO:0002003//angiotensin maturation;GO:0032091//negative regulation of protein binding;GO:0043312//neutrophil degranulation;GO:0006888//ER to Golgi vesicle-mediated transport;GO:1901214//regulation of neuron death","K08568//cathepsin X [EC:3.4.18.1]","EAW75449.1//cathepsin Z, isoform CRA_b [Homo sapiens]","3//A2MP1"]
[3140,7761,3.63,3.62,-0.00397985091254521,0.994122961570864,"*",0.96033,"MR1","GO:0005783//endoplasmic reticulum;GO:0042612//MHC class I protein complex;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane","GO:0032393//MHC class I receptor activity","GO:0050829//defense response to Gram-negative bacterium;GO:0032620//interleukin-17 production;GO:0006955//immune response;GO:0045087//innate immune response;GO:0002367//cytokine production involved in immune response;GO:0032611//interleukin-1 beta production;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I","K06751//major histocompatibility complex, class I","XP_016773699.1//PREDICTED: major histocompatibility complex class I-related gene protein isoform X5 [Pan troglodytes];XP_007987490.1//PREDICTED: major histocompatibility complex class I-related gene protein isoform X1 [Chlorocebus sabaeus];NP_001181928.1//major histocompatibility complex class I-related gene protein isoform 2 precursor [Homo sapiens];XP_017807155.1//major histocompatibility complex class I-related gene protein isoform X4 [Papio anubis];XP_007987492.1//PREDICTED: major histocompatibility complex class I-related gene protein isoform X3 [Chlorocebus sabaeus]","1//3;2//1"]
[57799,2616,10.92,10.89,-0.00396890220294556,0.984030735612794,"*",0.949472,"RAB40C","GO:0005768//endosome;GO:0030667//secretory granule membrane;GO:0008021//synaptic vesicle;GO:0005622//intracellular;GO:0005886//plasma membrane;GO:0048471//perinuclear region of cytoplasm","GO:0019003//GDP binding;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0072659//protein localization to plasma membrane;GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction","K07928//Ras-related protein Rab-40","NP_001166137.1//ras-related protein Rab-40C isoform b [Homo sapiens];XP_005081763.2//ras-related protein Rab-40C [Mesocricetus auratus]","4;1//3"]
[162427,3818,15.3,15.26,-0.0037766907454838,1.01897185848021,"*",0.988034,"RETREG3","GO:0016021//integral component of membrane","NA","GO:0010976//positive regulation of neuron projection development","K12855//pre-mRNA-processing factor 6;K01064//wingless-type MMTV integration site family, member 9","XP_004041670.2//PREDICTED: protein FAM134C isoform X1 [Gorilla gorilla gorilla]","3//A2MP1"]
[23293,4146,15.55,15.51,-0.00371589398187411,0.0138670594975576,"*",0.00497596,"SMG6","GO:0005634//nucleus;GO:0000781//chromosome, telomeric region;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005697//telomerase holoenzyme complex;GO:0035145//exon-exon junction complex;GO:0000333//telomerase catalytic core complex","GO:0003723//RNA binding;GO:0070182//DNA polymerase binding;GO:0004521//endoribonuclease activity;GO:0046872//metal ion binding;GO:0042162//telomeric DNA binding;GO:0043021//ribonucleoprotein complex binding;GO:0004540//ribonuclease activity;GO:0070034//telomerase RNA binding","GO:0006406//mRNA export from nucleus;GO:0032210//regulation of telomere maintenance via telomerase;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:1904354//negative regulation of telomere capping;GO:0051972//regulation of telomerase activity;GO:0035303//regulation of dephosphorylation;GO:0007004//telomere maintenance via telomerase;GO:0032204//regulation of telomere maintenance;GO:0043487//regulation of RNA stability","K11124//protein SMG6 [EC:3.1.-.-]","NP_001269255.1//telomerase-binding protein EST1A isoform 4 [Homo sapiens];EAW90558.1//hCG1813980, isoform CRA_c, partial [Homo sapiens];XP_016786654.1//PREDICTED: telomerase-binding protein EST1A isoform X3 [Pan troglodytes]","1//3;4"]
[5547,3670,19.73,19.68,-0.00366073538431879,0.919533934788395,"*",0.865078,"PRCP","GO:0070062//extracellular exosome;GO:0101003//ficolin-1-rich granule membrane;GO:0005764//lysosome;GO:0005886//plasma membrane;GO:0045178//basal part of cell;GO:0035577//azurophil granule membrane","GO:0004180//carboxypeptidase activity;GO:0004185//serine-type carboxypeptidase activity;GO:0008236//serine-type peptidase activity;GO:0008239//dipeptidyl-peptidase activity","GO:0043535//regulation of blood vessel endothelial cell migration;GO:0003085//negative regulation of systemic arterial blood pressure;GO:0007597//blood coagulation, intrinsic pathway;GO:0060055//angiogenesis involved in wound healing;GO:0042593//glucose homeostasis;GO:0097009//energy homeostasis;GO:0006508//proteolysis;GO:0043312//neutrophil degranulation;GO:2000377//regulation of reactive oxygen species metabolic process;GO:0002155//regulation of thyroid hormone mediated signaling pathway;GO:0002353//plasma kallikrein-kinin cascade","K01285//lysosomal Pro-X carboxypeptidase [EC:3.4.16.2]","NP_955450.2//lysosomal Pro-X carboxypeptidase isoform 2 precursor [Homo sapiens];NP_005031.1//lysosomal Pro-X carboxypeptidase isoform 1 preproprotein [Homo sapiens]","1//3;3//A2MP1"]
[102288414,666,96.94,96.7,-0.0035761928021965,1.01983310428498,"*",0.989316,"C11orf98","NA","NA","NA","NA","NP_001273015.1//uncharacterized protein C11orf98 [Homo sapiens]","1//3"]
[26063,1599,20.46,20.41,-0.00352996271260948,1.02172335495495,"*",0.993964,"DECR2","GO:0005777//peroxisome;GO:0005778//peroxisomal membrane","GO:0019166//trans-2-enoyl-CoA reductase (NADPH) activity;GO:0005102//receptor binding;GO:0008670//2,4-dienoyl-CoA reductase (NADPH) activity","GO:0006636//unsaturated fatty acid biosynthetic process;GO:0006631//fatty acid metabolic process;GO:0033540//fatty acid beta-oxidation using acyl-CoA oxidase","K13237//peroxisomal 2,4-dienoyl-CoA reductase [EC:1.3.1.34]","NP_065715.1//peroxisomal 2,4-dienoyl-CoA reductase [Homo sapiens]","3//A2MP1"]
[291,4420,4.1,4.09,-3.52306656369722E-3,1.01505754500226,"*",0.983476,"SLC25A4","GO:0005634//nucleus;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0043209//myelin sheath;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion","GO:0005471//ATP:ADP antiporter activity;GO:0015207//adenine transmembrane transporter activity;GO:0005215//transporter activity","GO:0006810//transport;GO:0055085//transmembrane transport;GO:0046902//regulation of mitochondrial membrane permeability;GO:0006091//generation of precursor metabolites and energy;GO:0008637//apoptotic mitochondrial changes;GO:0060546//negative regulation of necroptotic process;GO:0016032//viral process;GO:0050796//regulation of insulin secretion;GO:0000002//mitochondrial genome maintenance;GO:0015866//ADP transport","K05863//solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31","NP_001142.2//ADP/ATP translocase 1 [Homo sapiens]","3//A2MP1"]
[23125,4468,26.08,26.02,-3.32290751328206E-3,0.643671907407407,"*",0.487408,"CAMTA2","GO:0005634//nucleus","GO:0042826//histone deacetylase binding;GO:0003682//chromatin binding;GO:0043565//sequence-specific DNA binding;GO:0001077//transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding;GO:0008134//transcription factor binding","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0014898//cardiac muscle hypertrophy in response to stress","K21596//calmodulin-binding transcription activator","NP_001164639.1//calmodulin-binding transcription activator 2 isoform 3 [Homo sapiens];NP_001164638.1//calmodulin-binding transcription activator 2 isoform 4 [Homo sapiens];NP_001164637.1//calmodulin-binding transcription activator 2 isoform 2 [Homo sapiens];XP_011522049.1//PREDICTED: calmodulin-binding transcription activator 2 isoform X2 [Homo sapiens]","1//3;3//A2MP1"]
[9180,3994,27.14,27.08,-0.00319298184385746,0.921054042553191,"*",0.8672,"OSMR","GO:0016324//apical plasma membrane;GO:0005900//oncostatin-M receptor complex;GO:0005886//plasma membrane","GO:0004924//oncostatin-M receptor activity;GO:0004896//cytokine receptor activity;GO:0019838//growth factor binding","GO:0002675//positive regulation of acute inflammatory response;GO:0038165//oncostatin-M-mediated signaling pathway;GO:0034097//response to cytokine;GO:0008284//positive regulation of cell proliferation","K05057//oncostatin M receptor","NP_001161827.1//oncostatin-M-specific receptor subunit beta isoform 2 precursor [Homo sapiens];NP_001310436.1//oncostatin-M-specific receptor subunit beta isoform 4 precursor [Homo sapiens];NP_001310435.1//oncostatin-M-specific receptor subunit beta isoform 3 precursor [Homo sapiens];NP_003990.1//oncostatin-M-specific receptor subunit beta isoform 1 precursor [Homo sapiens]","1//3;2//1"]
[81554,2425,31.9,31.83,-0.00316926701631082,1.01648800204095,"*",0.997716,"RCC1L","GO:0005739//mitochondrion","GO:0003723//RNA binding","NA","K10615//E3 ubiquitin-protein ligase HERC4 [EC:2.3.2.26]","NP_683682.1//RCC1-like G exchanging factor-like protein isoform 2 [Homo sapiens];NP_110425.2//RCC1-like G exchanging factor-like protein isoform 1 [Homo sapiens];NP_001268370.1//RCC1-like G exchanging factor-like protein isoform 3 [Homo sapiens]","4;1//3;2//1"]
[129685,4323,9.22,9.2,-0.00313288948496302,0.999358,"*",0.999358,"TAF8","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005669//transcription factor TFIID complex;GO:0048471//perinuclear region of cytoplasm","GO:0003743//translation initiation factor activity;GO:0046982//protein heterodimerization activity","GO:0042795//snRNA transcription from RNA polymerase II promoter;GO:0045598//regulation of fat cell differentiation;GO:0030154//cell differentiation;GO:0001833//inner cell mass cell proliferation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051457//maintenance of protein location in nucleus","K14649//transcription initiation factor TFIID subunit 8","NP_612639.2//transcription initiation factor TFIID subunit 8 [Homo sapiens]","2//1"]
[163071,2527,4.61,4.6,-0.00313288948496302,1.01785923647165,"*",0.986764,"ZNF114","GO:0005622//intracellular","GO:0046872//metal ion binding;GO:0003676//nucleic acid binding","GO:0006355//regulation of transcription, DNA-templated","K09228//KRAB domain-containing zinc finger protein","XP_011936105.1//PREDICTED: zinc finger protein 114 [Cercocebus atys]","1//3;3//A2MP1"]
[54819,2216,4.82,4.81,-0.00299625245991967,1.01850933634661,"*",0.987458,"ZCCHC10","NA","GO:0008270//zinc ion binding;GO:0003676//nucleic acid binding","NA","K14438//chromodomain-helicase-DNA-binding protein 9 [EC:3.6.4.12];K08337//ubiquitin-like modifier-activating enzyme ATG7;K19613//leucine-rich repeat protein SHOC2;K13172//serine/arginine repetitive matrix protein 2","XP_531905.2//zinc finger CCHC domain-containing protein 10 isoform X2 [Canis lupus familiaris];OXB54752.1//hypothetical protein ASZ78_005815 [Callipepla squamata];NP_001033634.1//zinc finger CCHC domain-containing protein 10 [Bos taurus]","1//3;3//A2MP1;2//1"]
[11238,6032,4.99,4.98,-0.0028940732691796,1.02192617262941,"*",0.992434,"CA5B","GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion","GO:0008270//zinc ion binding;GO:0004089//carbonate dehydratase activity","GO:0015701//bicarbonate transport;GO:0006730//one-carbon metabolic process","K01672//carbonic anhydrase [EC:4.2.1.1]","NP_009151.1//carbonic anhydrase 5B, mitochondrial precursor [Homo sapiens]","3//A2MP1"]
[382,3939,35.82,35.75,-0.00282209543284716,1.02169259992279,"*",0.994062,"ARF6","GO:0016020//membrane;GO:0005938//cell cortex;GO:0005737//cytoplasm;GO:0055038//recycling endosome membrane;GO:0005829//cytosol;GO:0042584//chromaffin granule membrane;GO:0055037//recycling endosome;GO:0005886//plasma membrane;GO:0005769//early endosome;GO:0031527//filopodium membrane;GO:0070382//exocytic vesicle;GO:0070062//extracellular exosome;GO:0005925//focal adhesion;GO:0005622//intracellular;GO:0043209//myelin sheath;GO:0090543//Flemming body;GO:0005768//endosome;GO:0001726//ruffle;GO:0030139//endocytic vesicle;GO:0032154//cleavage furrow;GO:0005794//Golgi apparatus","GO:0031681//G-protein beta-subunit binding;GO:0047485//protein N-terminus binding;GO:0031996//thioesterase binding;GO:0005525//GTP binding;GO:0003924//GTPase activity","GO:0097284//hepatocyte apoptotic process;GO:0060998//regulation of dendritic spine development;GO:2000171//negative regulation of dendrite development;GO:0030866//cortical actin cytoskeleton organization;GO:0090162//establishment of epithelial cell polarity;GO:0016192//vesicle-mediated transport;GO:0034143//regulation of toll-like receptor 4 signaling pathway;GO:0007264//small GTPase mediated signal transduction;GO:1903078//positive regulation of protein localization to plasma membrane;GO:0030838//positive regulation of actin filament polymerization;GO:0033028//myeloid cell apoptotic process;GO:0015031//protein transport;GO:0050432//catecholamine secretion;GO:0051489//regulation of filopodium assembly;GO:0031529//ruffle organization;GO:0036010//protein localization to endosome;GO:0030036//actin cytoskeleton organization;GO:0001889//liver development;GO:0048261//negative regulation of receptor-mediated endocytosis;GO:0031584//activation of phospholipase D activity;GO:0061024//membrane organization;GO:0035020//regulation of Rac protein signal transduction;GO:0006928//movement of cell or subcellular component;GO:0007155//cell adhesion;GO:0051301//cell division;GO:0007049//cell cycle;GO:0034394//protein localization to cell surface","K07941//ADP-ribosylation factor 6","XP_005376889.2//PREDICTED: ADP-ribosylation factor 6 [Chinchilla lanigera]","3//A2MP1"]
[10670,1657,87.77,87.6,-0.00279703750668702,1.02178063301571,"*",0.993508,"RRAGA","GO:0005765//lysosomal membrane;GO:0005634//nucleus;GO:1990131//Gtr1-Gtr2 GTPase complex;GO:0034448//EGO complex;GO:0005829//cytosol;GO:1990130//GATOR1 complex;GO:0005764//lysosome;GO:0005737//cytoplasm","GO:0031625//ubiquitin protein ligase binding;GO:0046982//protein heterodimerization activity;GO:0005525//GTP binding;GO:0042803//protein homodimerization activity;GO:0051219//phosphoprotein binding;GO:0003924//GTPase activity","GO:0034198//cellular response to amino acid starvation;GO:0043200//response to amino acid;GO:0009267//cellular response to starvation;GO:0016567//protein ubiquitination;GO:0007050//cell cycle arrest;GO:0032008//positive regulation of TOR signaling;GO:0010506//regulation of autophagy;GO:1904263//positive regulation of TORC1 signaling;GO:0016241//regulation of macroautophagy;GO:0045919//positive regulation of cytolysis;GO:0042268//regulation of cytolysis;GO:0008219//cell death;GO:0006915//apoptotic process;GO:0071230//cellular response to amino acid stimulus;GO:1903432//regulation of TORC1 signaling;GO:0010507//negative regulation of autophagy;GO:0034613//cellular protein localization;GO:0019048//modulation by virus of host morphology or physiology","K16185//Ras-related GTP-binding protein A/B","AAH37615.1//Rraga protein, partial [Mus musculus]",4]
[1326,2951,5.28,5.27,-0.00273496772123906,1.00764612349515,"*",0.974592,"MAP3K8","GO:0005829//cytosol","GO:0005524//ATP binding;GO:0004672//protein kinase activity","NA","K04415//mitogen-activated protein kinase kinase kinase 8 [EC:2.7.11.25]","XP_018891147.1//PREDICTED: mitogen-activated protein kinase kinase kinase 8 isoform X1 [Gorilla gorilla gorilla];XP_019509950.1//PREDICTED: mitogen-activated protein kinase kinase kinase 8 isoform X1 [Hipposideros armiger]","1//3;3//A2MP1"]
[54788,3596,21.99,21.95,-0.00262666443224754,0.949216922915161,"*",0.904234,"DNAJB12","GO:0016020//membrane;GO:0031965//nuclear membrane;GO:0005783//endoplasmic reticulum;GO:0030176//integral component of endoplasmic reticulum membrane","GO:0030544//Hsp70 protein binding","GO:0036503//ERAD pathway;GO:0051085//chaperone cofactor-dependent protein refolding;GO:0071218//cellular response to misfolded protein;GO:0043623//cellular protein complex assembly","K09518//DnaJ homolog subfamily B member 12","NP_001002762.2//dnaJ homolog subfamily B member 12 [Homo sapiens]","4;2//1"]
[7536,3187,175.39,175.12,-0.00222263409366299,0.785678701133145,"*",0.69449,"SF1","GO:0005840//ribosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0016604//nuclear body","GO:0003723//RNA binding;GO:0003714//transcription corepressor activity;GO:0045131//pre-mRNA branch point binding;GO:0042802//identical protein binding;GO:0008270//zinc ion binding","GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0000398//mRNA splicing, via spliceosome;GO:0006355//regulation of transcription, DNA-templated;GO:0030575//nuclear body organization;GO:0030238//male sex determination;GO:0006351//transcription, DNA-templated;GO:0050810//regulation of steroid biosynthetic process;GO:0000389//mRNA 3'-splice site recognition;GO:0033327//Leydig cell differentiation;GO:0000245//spliceosomal complex assembly","K13095//splicing factor 1","NP_973726.2//splicing factor 1 isoform 4 [Homo sapiens];EDL33241.1//splicing factor 1, isoform CRA_a, partial [Mus musculus];NP_001171501.1//splicing factor 1 isoform 6 [Homo sapiens];XP_015333689.1//PREDICTED: splicing factor 1 isoform X4 [Marmota marmota marmota];NP_001333293.1//splicing factor 1 isoform 10 [Homo sapiens];NP_973724.1//splicing factor 1 isoform 2 [Homo sapiens];NP_001333292.1//splicing factor 1 isoform 9 [Homo sapiens];XP_015333691.1//PREDICTED: splicing factor 1 isoform X6 [Marmota marmota marmota];XP_012353274.1//PREDICTED: splicing factor 1 isoform X2 [Nomascus leucogenys];EDL33242.1//splicing factor 1, isoform CRA_b, partial [Mus musculus]","1//3;3//A2MP1;2//1"]
[153527,1644,77.14,77.03,-0.00205872065158588,1.01640984512045,"*",0.985168,"ZMAT2","NA","GO:0008270//zinc ion binding;GO:0003676//nucleic acid binding","NA","K12848//U4/U6.U5 tri-snRNP component SNU23","XP_004420129.2//PREDICTED: zinc finger matrin-type protein 2 [Ceratotherium simum simum]","2//1"]
[56850,3052,7.75,7.74,-1.86274401718951E-3,1.01357163241286,"*",0.981148,"GRIPAP1","GO:0043231//intracellular membrane-bounded organelle;GO:0030425//dendrite;GO:0030424//axon;GO:0005654//nucleoplasm;GO:0072562//blood microparticle;GO:0030054//cell junction;GO:0098837//postsynaptic recycling endosome;GO:0055038//recycling endosome membrane;GO:0031901//early endosome membrane;GO:0005829//cytosol","NA","GO:1905244//regulation of modification of synaptic structure;GO:0098887//neurotransmitter receptor transport, endosome to postsynaptic membrane","K18626//trichohyalin","NP_064522.3//GRIP1-associated protein 1 [Homo sapiens]",4]
[54433,1235,17.1,17.08,-0.00168835015277009,0.981878631421706,"*",0.946412,"GAR1","GO:0019013//viral nucleocapsid;GO:0031429//box H/ACA snoRNP complex","GO:0003723//RNA binding","GO:0006364//rRNA processing;GO:0001522//pseudouridine synthesis","K11128//H/ACA ribonucleoprotein complex subunit 1","XP_009446402.2//PREDICTED: H/ACA ribonucleoprotein complex subunit 1 [Pan troglodytes]","3//A2MP1;2//1"]
[9368,2032,38.9,38.86,-0.00148425428820965,1.0152025016152,"*",0.98368,"SLC9A3R1","GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0031526//brush border membrane;GO:0071944//cell periphery;GO:0031982//vesicle;GO:0005737//cytoplasm;GO:0012505//endomembrane system;GO:0015629//actin cytoskeleton;GO:0070062//extracellular exosome;GO:0032426//stereocilium tip;GO:0005902//microvillus;GO:0030175//filopodium;GO:0048471//perinuclear region of cytoplasm;GO:0001726//ruffle;GO:0045121//membrane raft;GO:0097225//sperm midpiece;GO:0031528//microvillus membrane","GO:0032947//protein complex scaffold activity;GO:0045159//myosin II binding;GO:0005102//receptor binding;GO:0043621//protein self-association;GO:0070851//growth factor receptor binding;GO:0031698//beta-2 adrenergic receptor binding;GO:0019902//phosphatase binding;GO:0030165//PDZ domain binding;GO:0008013//beta-catenin binding;GO:0017081//chloride channel regulator activity;GO:0050780//dopamine receptor binding;GO:0032403//protein complex binding","GO:0045859//regulation of protein kinase activity;GO:0030643//cellular phosphate ion homeostasis;GO:0070293//renal absorption;GO:0097291//renal phosphate ion absorption;GO:0034635//glutathione transport;GO:0051898//negative regulation of protein kinase B signaling;GO:0007097//nuclear migration;GO:0008285//negative regulation of cell proliferation;GO:0032782//bile acid secretion;GO:0030036//actin cytoskeleton organization;GO:0045930//negative regulation of mitotic cell cycle;GO:0008361//regulation of cell size;GO:0003096//renal sodium ion transport;GO:0008360//regulation of cell shape;GO:0030033//microvillus assembly;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0035414//negative regulation of catenin import into nucleus;GO:0016055//Wnt signaling pathway;GO:0014067//negative regulation of phosphatidylinositol 3-kinase signaling;GO:0006461//protein complex assembly;GO:0060088//auditory receptor cell stereocilium organization;GO:0044062//regulation of excretion;GO:0010642//negative regulation of platelet-derived growth factor receptor signaling pathway;GO:0007191//adenylate cyclase-activating dopamine receptor signaling pathway;GO:0051683//establishment of Golgi localization;GO:0045198//establishment of epithelial cell apical/basal polarity;GO:0072659//protein localization to plasma membrane;GO:0032415//regulation of sodium:proton antiporter activity;GO:0030336//negative regulation of cell migration;GO:0032416//negative regulation of sodium:proton antiporter activity;GO:0060158//phospholipase C-activating dopamine receptor signaling pathway;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway;GO:0007605//sensory perception of sound;GO:0022612//gland morphogenesis","K13365//Na(+)/H(+) exchange regulatory cofactor NHE-RF1","AAH49220.1//SLC9A3R1 protein, partial [Homo sapiens]",4]
[91949,2943,10.51,10.5,-1.37334140869342E-3,1.02206630106973,"*",0.99289,"COG7","GO:0032588//trans-Golgi network membrane;GO:0005730//nucleolus;GO:0017119//Golgi transport complex;GO:0005794//Golgi apparatus;GO:0000139//Golgi membrane","NA","GO:0006486//protein glycosylation;GO:0034067//protein localization to Golgi apparatus;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0007030//Golgi organization;GO:0006886//intracellular protein transport;GO:0033365//protein localization to organelle;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0050821//protein stabilization","K20294//conserved oligomeric Golgi complex subunit 7","NP_705831.1//conserved oligomeric Golgi complex subunit 7 [Homo sapiens]","3//A2MP1"]
[90557,1708,10.62,10.61,-0.00135910988938885,0.857857144847367,"*",0.786378,"CCDC74A","NA","NA","NA","K17776//metaxin;K13172//serine/arginine repetitive matrix protein 2","NP_001245235.1//coiled-coil domain-containing protein 74A isoform 4 [Homo sapiens];NP_001245233.1//coiled-coil domain-containing protein 74A isoform 2 [Homo sapiens];NP_001335976.1//coiled-coil domain-containing protein 74A isoform 11 [Homo sapiens];NP_001335975.1//coiled-coil domain-containing protein 74A isoform 10 [Homo sapiens];NP_001335972.1//coiled-coil domain-containing protein 74A isoform 7 [Homo sapiens];NP_001335971.1//coiled-coil domain-containing protein 74A isoform 6 [Homo sapiens];NP_001335974.1//coiled-coil domain-containing protein 74A isoform 9 [Homo sapiens];NP_620125.1//coiled-coil domain-containing protein 74A isoform 1 [Homo sapiens];NP_001335970.1//coiled-coil domain-containing protein 74A isoform 5 [Homo sapiens];NP_001335973.1//coiled-coil domain-containing protein 74A isoform 8 [Homo sapiens];NP_001245234.1//coiled-coil domain-containing protein 74A isoform 3 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[348235,2994,37.03,37,-0.00116927876795536,1.01283074160792,"*",0.980304,"SKA2","GO:0005829//cytosol;GO:0000940//condensed chromosome outer kinetochore;GO:0005737//cytoplasm;GO:0005876//spindle microtubule","GO:0008017//microtubule binding","GO:0000278//mitotic cell cycle;GO:0007059//chromosome segregation;GO:0007062//sister chromatid cohesion;GO:0031110//regulation of microtubule polymerization or depolymerization;GO:0051301//cell division","K12581//CCR4-NOT transcription complex subunit 7/8;K01064//wingless-type MMTV integration site family, member 9","NP_001094065.1//spindle and kinetochore-associated protein 2 isoform 2 [Homo sapiens];NP_001317328.1//spindle and kinetochore-associated protein 2 isoform 3 [Homo sapiens];NP_872426.1//spindle and kinetochore-associated protein 2 isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[79017,1197,37.99,37.96,-0.00113971964391311,0.697317674481515,"*",0.580938,"GGCT","GO:0070062//extracellular exosome;GO:0005829//cytosol","GO:0003839//gamma-glutamylcyclotransferase activity;GO:0042803//protein homodimerization activity","GO:0006750//glutathione biosynthetic process;GO:0001836//release of cytochrome c from mitochondria","K00682//gamma-glutamylcyclotransferase [EC:4.3.2.9]","NP_001186744.1//gamma-glutamylcyclotransferase isoform 2 [Homo sapiens];NP_001186745.1//gamma-glutamylcyclotransferase isoform 3 [Homo sapiens];NP_001186746.1//gamma-glutamylcyclotransferase isoform 4 [Homo sapiens];NP_076956.1//gamma-glutamylcyclotransferase isoform 1 [Homo sapiens]","1//3;3//A2MP1"]
[55761,4184,16.65,16.64,-0.000866743817532217,0.986900616162926,"*",0.95255,"TTC17","GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0005886//plasma membrane;GO:0005737//cytoplasm","NA","GO:0044782//cilium organization;GO:0030041//actin filament polymerization","NA","NP_060729.2//tetratricopeptide repeat protein 17 isoform 1 [Homo sapiens];NP_001294872.1//tetratricopeptide repeat protein 17 isoform 2 [Homo sapiens]","1//3;5"]
[221545,1479,18.58,18.57,-0.000776686447231918,0.992986829401089,"*",0.959046,"C6orf136","GO:0005739//mitochondrion","NA","NA","K03006//DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6];K05853//Ca2+ transporting ATPase, sarcoplasmic/endoplasmic reticulum [EC:3.6.3.8];K21125//mucin-5AC","NP_001103408.1//uncharacterized protein C6orf136 isoform 1 [Homo sapiens];NP_659466.2//uncharacterized protein C6orf136 isoform 2 [Homo sapiens];XP_003897351.2//LOW QUALITY PROTEIN: uncharacterized protein C6orf136 homolog [Papio anubis]","1//3;3//A2MP1;2//1"]
[83637,5063,21.86,21.85,-0.000660121283943764,1.00757072587222,"*",0.974456,"ZMIZ2","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0043596//nuclear replication fork","GO:0008270//zinc ion binding;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity","GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated","K00164//2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2];K16064//E3 SUMO-protein ligase PIAS3;K04706//E3 SUMO-protein ligase PIAS1;K06794//neurocan core protein","NP_113637.3//zinc finger MIZ domain-containing protein 2 isoform 1 [Homo sapiens];NP_777589.2//zinc finger MIZ domain-containing protein 2 isoform 2 [Homo sapiens];NP_001287888.1//zinc finger MIZ domain-containing protein 2 isoform 3 [Homo sapiens]","1//3;3//A2MP1;2//1"]
[64841,3945,23.35,23.34,-0.000617988889676312,0.996584239243131,"*",0.96277,"GNPNAT1","NA","NA","NA","K00621//glucosamine-phosphate N-acetyltransferase [EC:2.3.1.4]","XP_017704960.1//PREDICTED: glucosamine 6-phosphate N-acetyltransferase isoform X1 [Rhinopithecus bieti]","3//A2MP1"]
[27044,3678,62.59,62.57,-0.000461072244540993,0.977936301287889,"*",0.941204,"SND1","GO:0016020//membrane;GO:0070062//extracellular exosome;GO:0005634//nucleus;GO:0042470//melanosome;GO:0005737//cytoplasm;GO:0097433//dense body;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0016442//RISC complex","GO:0003723//RNA binding;GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0004518//nuclease activity;GO:0045296//cadherin binding","GO:0006401//RNA catabolic process;GO:0001649//osteoblast differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0031047//gene silencing by RNA;GO:0016032//viral process","K15979//staphylococcal nuclease domain-containing protein 1","BAD92747.1//EBNA-2 co-activator variant, partial [Homo sapiens]","3//A2MP1"]
[79833,705,33.91,33.9,-4.25511001724551E-4,1.01387024481086,"*",0.981564,"GEMIN6","GO:0034719//SMN-Sm protein complex;GO:0032797//SMN complex;GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0097504//Gemini of coiled bodies;GO:0005829//cytosol;GO:0005737//cytoplasm","NA","GO:0000398//mRNA splicing, via spliceosome;GO:0051170//nuclear import;GO:0000245//spliceosomal complex assembly;GO:0000387//spliceosomal snRNP assembly","K13134//gem associated protein 6","NP_079051.9//gem-associated protein 6 [Homo sapiens]","9//1"]
[29098,936,42.7,42.69,-0.00033790726021438,0.792420472182999,"*",0.702632,"RANGRF","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005791//rough endoplasmic reticulum;GO:0005737//cytoplasm;GO:0005901//caveola;GO:0005829//cytosol;GO:0014704//intercalated disc;GO:0005886//plasma membrane","GO:0005087//Ran guanyl-nucleotide exchange factor activity;GO:0044325//ion channel binding;GO:0008536//Ran GTPase binding;GO:0017080//sodium channel regulator activity;GO:0008565//protein transporter activity;GO:0005085//guanyl-nucleotide exchange factor activity","GO:0032527//protein exit from endoplasmic reticulum;GO:0098909//regulation of cardiac muscle cell action potential involved in regulation of contraction;GO:2000010//positive regulation of protein localization to cell surface;GO:0043547//positive regulation of GTPase activity;GO:0002027//regulation of heart rate;GO:0098905//regulation of bundle of His cell action potential;GO:2000649//regulation of sodium ion transmembrane transporter activity;GO:1902305//regulation of sodium ion transmembrane transport;GO:0003254//regulation of membrane depolarization;GO:1903078//positive regulation of protein localization to plasma membrane;GO:0006888//ER to Golgi vesicle-mediated transport;GO:1900825//regulation of membrane depolarization during cardiac muscle cell action potential;GO:0042391//regulation of membrane potential","K17495//CUB and sushi domain-containing protein;K15117//solute carrier family 25, member 34/35","NP_001171273.1//ran guanine nucleotide release factor isoform C [Homo sapiens];NP_001317056.1//ran guanine nucleotide release factor isoform D [Homo sapiens];NP_057576.2//ran guanine nucleotide release factor isoform A [Homo sapiens]","4;1//3"]
[9550,1611,46.18,46.17,-0.000312440724748762,1.00033928777771,"*",0.966836,"ATP6V1G1","GO:0005765//lysosomal membrane;GO:0070062//extracellular exosome;GO:0005829//cytosol;GO:0016471//vacuolar proton-transporting V-type ATPase complex;GO:0005886//plasma membrane","GO:0008553//hydrogen-exporting ATPase activity, phosphorylative mechanism;GO:0051117//ATPase binding","GO:0016241//regulation of macroautophagy;GO:0006879//cellular iron ion homeostasis;GO:0008286//insulin receptor signaling pathway;GO:0034220//ion transmembrane transport;GO:0033572//transferrin transport;GO:0036295//cellular response to increased oxygen levels;GO:0090383//phagosome acidification;GO:0015992//proton transport","K02152//V-type H+-transporting ATPase subunit G","NP_004879.1//V-type proton ATPase subunit G 1 [Homo sapiens]","3//A2MP1"]
[6009,2092,66.93,66.92,-2.15568926944165E-4,0.988517357800545,"*",0.954358,"RHEB","GO:0030425//dendrite;GO:0016020//membrane;GO:0005765//lysosomal membrane;GO:0070062//extracellular exosome;GO:0043025//neuronal cell body;GO:0000139//Golgi membrane;GO:0005681//spliceosomal complex;GO:0005829//cytosol;GO:0005789//endoplasmic reticulum membrane","GO:0000287//magnesium ion binding;GO:0019003//GDP binding;GO:0005525//GTP binding;GO:0019901//protein kinase binding;GO:0003924//GTPase activity","GO:0016241//regulation of macroautophagy;GO:0032006//regulation of TOR signaling;GO:0007165//signal transduction;GO:0048714//positive regulation of oligodendrocyte differentiation;GO:0032008//positive regulation of TOR signaling;GO:0007050//cell cycle arrest;GO:2000074//regulation of type B pancreatic cell development;GO:0048168//regulation of neuronal synaptic plasticity;GO:0007264//small GTPase mediated signal transduction","K07208//Ras homolog enriched in brain","NP_005605.1//GTP-binding protein Rheb [Homo sapiens]","3//A2MP1"]