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[null,"Table 1: Differentially methylated cytosines (DMCs) found in this study between pre- and post-challenge sea bass"]
[]
[null,"D. labrax LG","Ensembl LG","q-value","methylation difference (%)","D. labrax Name","Gene ID","Gene Name","Location","References"]
[]
[null,"LG1A","HG916837.1",0,"-21,40","DLAgn_00094580","FOXJ3","forkhead box protein J3","gb","[64]"]
[null,"LG1A","HG916837.1",0,"-21,67"," -"," - "," -","gb"," \" "]
[null,"LG1A","HG916837.1",0,"-15,51"," -"," -"," -","gb"," \" "]
[null,"LG3","HG916843.1","1,54E-95","18,14","DLAgn_00141440","ABLIM2","actin binding LIM protein family -- member 2","gb","[64]"]
[null,"LG4","HG916844.1","1,08E-84","16,41","DLAgn_00145290","CELA3b","proproteinase E-like (elastase 2)"]
[null,"LG4","HG916844.1",0,"21,38","DLAgn_00146200","NCBP2","nuclear cap-binding protein subunit 2","int.","[63,64]"]
[null,"LG5","HG916845.1","3,67E-265","21,91","DLAgn_00159160","CILP1","cartilage intermediate layer protein 1","gb","[63]"]
[null,"LG5","HG916845.1","8,93E-89","16,64","DLAgn_00159900","GRPT1","growth hormone regulated TBC protein 1","gb"]
[null,"LG6","HG916846.1","6,44E-245","20,44","DLAgn_00164450","GLG1a","golgi glycoprotein 1","gb","[64,65]"]
[null,"LG6","HG916846.1",0,"-21,01","DLAgn_00166360","GDPGP1","gdp-d-glucose phosphorylase 1","exon"]
[null,"LG6","HG916846.1",0,"-18,98","DLAgn_00172370","KBTBD13 ","kelch repeat and btb domain-containing protein 13-like","int."]
[null,"LG6","HG916846.1",0,"-18,18"," -"," -"," -","int."]
[null,"LG6","HG916846.1",0,"-16,12"," -"," -"," -","int."]
[null,"LG8","HG916848.1","2,77E-247","22,52","DLAgn_00186250","BTPF","nucleosome-remodeling factor subunit bptf","gb"]
[null,"LG10","HG916827.1","2,44E-79","15,44","DLAgn_00005890","PBX1","pre-B-cell leukemia homeobox 1","gb","[64]"]
[null,"LG10","HG916827.1","6,98E-125","21,55","DLAgn_00006210","ADCY1","adenylate cyclase 1 (brain)","gb","[64,65]"]
[null,"LG11","HG916828.1",0,"27,70","DLAgn_00016970","MMNR2","multimerin 2a Precursor Elastin Microfibril Interface Located Elastin Microfibril Interfacer","gb"]
[null,"LG12","HG916829.1",0,"22,32","DLAgn_00019700","FBXO33","F-box protein 33","int."]
[null,"LG12","HG916829.1","1,23E-128","20,01","DLAgn_00025280","SASH1A","Sam and sh3 domain-containing protein 1-like","int.","[64,65]"]
[null,"LG14","HG916831.1","1,48E-53","15,74","DLAgn_00037440","COL4A5","Collagen type IV alpha 5 chain","int.","[64,65]"]
[null,"LG14","HG916831.1",0,"42,05","DLAgn_00037440","COL4A5"," \"","gb"," \" "]
[null,"LG14","HG916831.1",0,"22,46","DLAgn_00038760","ROBO3","Roundabout homolog 2-like","int.","[64,65]"]
[null,"LG14","HG916831.1","5,22E-212","17,93","DLAgn_00044110","CLDN4","Claudin 4","gb","[64]"]
[null,"LG14","HG916831.1","1,25E-155","27,48","DLAgn_00046110","TMEM132E","Transmembrane protein 132e","gb"]
[null,"LG16","HG916833.1","2,78E-168","26,24","DLAgn_00063590","CSMD3a","CUB and Sushi multiple domains 3a","gb","[64]"]
[null,"LG16","HG916833.1","9,78E-92","17,12","DLAgn_00063770","TRMT11","tRNA methyltransferase 11 homolog","int.","[64]"]
[null,"LG16","HG916833.1","8,81E-215","17,80","DLAgn_00064610","FURIN","Furin-like protease kpc-1","gb","[63,64]"]
[null,"LG16","HG916833.1",0,"17,76","DLAgn_00064820","SPIRE1b","Protein spire homolog 1-like","gb","[64]"]
[null,"LG17","HG916834.1","1,91E-82","18,84","DLAgn_00073160 ; DLAgn_00073170","PLG (sense); SLC22A2 (antisense)","Plasminogen (sense) / Solute carrier family 22 member 2-like (antisense)","gb / 3'UTR","[64]"]
[null,"LG17","HG916834.1","1,28E-231","19,86","DLAgn_00073770","RRM2","Ribonucleotide reductase regulatory subunit M2","gb","[63,64]"]
[null,"LG20","HG916840.1","2,76E-207","15,01","DLAgn_00114460","TNKSb","Tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase b","gb","[64,65]"]
[null,"LG20","HG916840.1","1,34E-115","15,35","DLAgn_00114810","LRRTM4L2","Leucine-rich repeat transmembrane neuronal protein 4-like","gb"]
[null,"LG20","HG916840.1","3,78E-68","15,32","DLAgn_00116160 ; DLAgn_00116150","FICD (sense) ; SART3 (antisense)","Adenosine monophosphate-protein transferase ficd-like (sense) / Spliceosome associated factor 3, U4/U6 recycling protein (antisense)","gb","[64]"]
[null,"LG20","HG916840.1","1,02E-88","18,04","DLAgn_00121270",null,"Coding region of a truncated Non LTR Retrotransposable Element (RTE) RET-1_AFC","rr"]
[null,"LG20","HG916840.1",0,"35,61","DLAgn_00122640","BMP3","Bone morphogenetic protein 3","gb","[64]"]
[null,"LG20","HG916840.1",0,"15,40","DLAgn_00124110","ZMAT4","Zinc finger matrin-type 4b","gb","[64]"]
[null,"LG22-25","HG916841.1","7,62E-96","16,89","DLAgn_00125750","NOL4LB","Nucleolar protein 4-like b","gb","[65]"]
[null,"LG22-25","HG916841.1","3,26E-99","15,05","DLAgn_00132500","CCDC30","Coiled-coil domain containing protein 30 like","gb","[64]"]
[null,"LG24","HG916842.1","2,81E-43","-15,63","DLAgn_00136190","GLI2","Zinc finger protein gli2-like","gb","[63,64]"]
[null,"LG24","HG916842.1","2,87E-112","16,47","DLAgn_00136980","LRRC3","Leucine rich repeat containing 3","int."]
[null,"LG24","HG916842.1",0,"30,68","DLAgn_00137190","UNC80","Protein unc-80 homolog isoform 2","gb","[64,65]"]
[null,"LG24","HG916842.1",0,"15,42","DLAgn_00137560","CHN1","N-chimerin","gb","[64]"]
[null,"LG24","HG916842.1","9,47E-204","17,08","DLAgn_00139980","PTGFRN ","Prostaglandin f2 receptor negative regulator","gb","[64,65]"]
[null,"LGx","HG916850.1","4,18E-251","19,94","DLAgn_00209310","MYF5","Myogenic factor 5","gb"]
[null,"LGx","HG916850.1","4,52E-204","23,46","DLAgn_00209760","CELF2","Cugbp elav-like family member 2","gb","[63,64]"]
[null,"SB-UN","HG916851.1","1,61E-152","16,29","DLAgn_00218300","PRKCQ","Protein kinase c theta type","int. ","[64]"]
[null,"SB-UN","HG916851.1","1,09E-120","16,34","DLAgn_00220000","PTPRB","Protein tyrosine phosphatase receptor type B","gb","[64]"]
[null,"SB-UN","HG916851.1","6,07E-154","18,95","DLAgn_00222790","NPAS3","Neuronal PAS domain-containing protein 3-like","gb","[64]"]
[null,"SB-UN","HG916851.1",0,"-21,55","DLAgn_00227120","CRTC2","CREB regulated transcription coactivator 2","gb","[64]"]
[null,"SB-UN","HG916851.1","6,11E-56","15,79"," -"," -"," -","gb"," \" "]
[null,"SB-UN","HG916851.1","4,15E-61","17,53","DLAgn_00227130","DENND4B","Denn domain-containing protein 4b","gb","[64]"]
[null,"SB-UN","HG916851.1","1,51E-46","15,84","DLAgn_00236500","GFRA2","GDNF family receptor alpha-2","gb","[64]"]
[null,"SB-UN","HG916851.1",0,"46,39","DLAgn_00238280","DLG1","Disks large homolog 1-like","gb","[63,65,66]"]
[null,"SB-UN","HG916851.1","9,43E-157","26,15","DLAgn_00242570","BTR30","E3 ubiquitin-protein ligase TRIM39-like (bloodthirsty-related gene family, member 30)","gb"," "]
[null,"SB-UN","HG916851.1","6,99E-209","-17,71"," -"," -"," -","gb"]
[null,"SB-UN","HG916851.1","2,11E-216","-27,49","DLAgn_00244380","GMPPB","GDP-mannose pyrophosphorylase B","exon","[64]"]
[null,"SB-UN","HG916851.1","5,09E-256","20,97","DLAgn_00245980","MATR3","Matrin-3","exon","[64]"]
[]
[null,"Location on the European sea bass linkage groups (LGs) of the 57 differentially methylated cytosines (DMCs) found in this study between pre- and post-challenge individuals. For each DMC, the false-discovery rate adjusted q-values at the nominal q = 0.001 cut-off threshold are reported, together with their methylation difference. Gene names and gene symbols (IDs) of DMC-related genes (n = 51) are reported. The location of each DMC is given (gb: gene body, int.: intergenic, 3’UTR or rr: repeat region). We did not arbitrarily defined promoter regions in this study. The right column indicates high-throughput stress-related neurotranscriptomic studies in which some of these DMC-related genes were reported as differentially expressed. It does not mean that these DMC related genes are involved only in brain-derived studies of stress (see Discussion for few reports). LGs are labelled as in [19]. An extended version of this table reporting annotations and further useful information are offered in Additional File 3."]